A0A075BQY3_DROME Loading...

Cytochrome P450

AlphaFold DB , UniProt , Accession A0A075BQY3, Species DROME (Drosophila melanogaster, Fruit fly), Gene Cyp6a2, Length 506 aa.

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Site Residue pLDDT pLDDT confidence pLDDT10 pLDDT10 confidence SASA SASA [Ų] SASA10 SASA10 [Ų] RSA RSA unformatted RSA10 RSA10 unformatted Surface Surface10 (not used) Disorder (not used) Disorder Sec. str. Secondary structure Isomer Phi (φ) Psi (ψ) Omega (ω) Chi 1 (χ1) Chi 2 (χ2) Chi 3 (χ3) Chi 4 (χ4) Chi 5 (χ5) Tau (τ) Contacts (colored by PAE) Contact details
1M71.3Confident89.9Confident172 Ų172111.9 Ų111.985%0.84757%0.573SS**  0-57.60-161165.968.700112.1V3 L4 I5M1-V3 PolarHBondContact O-N 2.82Å; M1-L4 PolarHBondContact O-N 3.13Å; M1-I5 HydrophobicContact CG-CD1 4.28Å; M1-I5 PolarHBondContact O-N 3.27Å
2F85.4Confident90Very high137 Ų137107.9 Ų107.960%0.60156%0.562SS**Hα-helixtrans-58.9-38.8180-65.8-76.3000115.1L4 I5 Y6F2-L4 VanDerWaalsContact C-N 3.33Å; F2-L4 PolarHBondContact O-N 3.07Å; F2-I5 PolarHBondContact O-N 3.22Å; F2-I5 VanDerWaalsContact O-N 3.17Å; F2-Y6 HydrophobicContact CB-CD2 4.38Å; F2-Y6 HydrophobicContact CB-CE2 4.09Å; F2-Y6 WeakPolarHBondContact O-CD2 3.43Å; F2-Y6 PolarHBondContact O-N 2.82Å
3V88.9Confident90.2Very high106 Ų106104.9 Ų104.964%0.64256%0.556SS**Hα-helixtrans-60.8-40.5176.91780000112.3M1 I5 Y6 L7M1-V3 PolarHBondContact O-N 2.82Å; V3-I5 VanDerWaalsContact C-N 3.34Å; V3-Y6 PolarHBondContact O-N 2.9Å; V3-L7 HydrophobicContact CG1-CD1 4.11Å; V3-L7 WeakPolarHBondContact O-CB 3.3Å; V3-L7 WeakPolarHBondContact O-CG 3.2Å; V3-L7 PolarHBondContact O-N 2.85Å
4L89.9Confident90.3Very high129 Ų129104.6 Ų104.668%0.67555%0.554SS**Hα-helixtrans-67.3-36.6176.8-68.3172000111.5M1 F2 L8M1-L4 PolarHBondContact O-N 3.13Å; F2-L4 VanDerWaalsContact C-N 3.33Å; F2-L4 PolarHBondContact O-N 3.07Å; L4-L8 WeakPolarHBondContact O-CB 3.39Å; L4-L8 PolarHBondContact O-N 2.83Å
5I92.6Very high90.1Very high79 Ų79104.9 Ų104.941%0.40556%0.555SS.*Hα-helixtrans-66.4-46176-64.5169.2000110.5M1 F2 V3 L7 L8 I9M1-I5 HydrophobicContact CG-CD1 4.28Å; M1-I5 PolarHBondContact O-N 3.27Å; F2-I5 PolarHBondContact O-N 3.22Å; F2-I5 VanDerWaalsContact O-N 3.17Å; V3-I5 VanDerWaalsContact C-N 3.34Å; I5-L7 PolarHBondContact O-N 2.91Å; I5-L8 PolarHBondContact O-N 2.77Å; I5-I9 HydrophobicContact CG2-CD1 3.85Å; I5-I9 WeakPolarHBondContact O-CG1 3.24Å; I5-I9 PolarHBondContact O-N 3.36Å
6Y93.9Very high90Very high159 Ų159102.1 Ų102.162%0.62455%0.551SS**Hα-helixtrans-64-40.2176.8-71.2-58.7000112.6F2 V3 I9 A10F2-Y6 HydrophobicContact CB-CD2 4.38Å; F2-Y6 HydrophobicContact CB-CE2 4.09Å; F2-Y6 WeakPolarHBondContact O-CD2 3.43Å; F2-Y6 PolarHBondContact O-N 2.82Å; V3-Y6 PolarHBondContact O-N 2.9Å; Y6-I9 PolarHBondContact O-N 2.72Å; Y6-A10 VanDerWaalsContact O-CB 3.31Å; Y6-A10 WeakPolarHBondContact O-CB 3.17Å; Y6-A10 PolarHBondContact O-N 2.69Å
7L92.9Very high90Very high94 Ų94103.9 Ų103.949%0.49255%0.55SS..Hα-helixtrans-61.8-44.4173.4-78.5168.8000111.5V3 I5 A10 I11V3-L7 HydrophobicContact CG1-CD1 4.11Å; V3-L7 WeakPolarHBondContact O-CB 3.3Å; V3-L7 WeakPolarHBondContact O-CG 3.2Å; V3-L7 PolarHBondContact O-N 2.85Å; I5-L7 PolarHBondContact O-N 2.91Å; L7-A10 PolarHBondContact O-N 3.27Å; L7-I11 WeakPolarHBondContact O-CB 3.17Å; L7-I11 WeakPolarHBondContact O-CG1 3.18Å; L7-I11 PolarHBondContact O-N 3.16Å
8L93.4Very high89.7Confident115 Ų115102.1 Ų102.160%0.60254%0.54SS*.Hα-helixtrans-60.6-47.6177.1-168.578.9000111.1L4 I5 A10 I11 S12L4-L8 WeakPolarHBondContact O-CB 3.39Å; L4-L8 PolarHBondContact O-N 2.83Å; I5-L8 PolarHBondContact O-N 2.77Å; L8-A10 PolarHBondContact O-N 2.63Å; L8-I11 PolarHBondContact O-N 2.58Å; L8-S12 WeakPolarHBondContact O-CB 3.31Å; L8-S12 PolarHBondContact O-N 2.88Å; L8-S12 PolarHBondContact O-OG 2.9Å; L8-S12 VanDerWaalsContact O-OG 3.05Å
9I94.3Very high89.5Confident91 Ų91101.7 Ų101.747%0.46753%0.531SS..Hα-helixtrans-62.2-42.9178.6-67.6167.3000111.4I5 Y6 S12 S13I5-I9 HydrophobicContact CG2-CD1 3.85Å; I5-I9 WeakPolarHBondContact O-CG1 3.24Å; I5-I9 PolarHBondContact O-N 3.36Å; Y6-I9 PolarHBondContact O-N 2.72Å; I9-S12 PolarHBondContact O-N 3.15Å; I9-S13 VanDerWaalsContact O-CB 3.25Å; I9-S13 WeakPolarHBondContact O-CB 3.46Å; I9-S13 PolarHBondContact O-N 3.39Å; I9-S13 PolarHBondContact O-OG 2.88Å
10A93.3Very high89.3Confident57 Ų57102.6 Ų102.647%0.47153%0.532SS..Hα-helixtrans-63.5-44.917800000111.3Y6 L7 L8 S13 L14Y6-A10 VanDerWaalsContact O-CB 3.31Å; Y6-A10 WeakPolarHBondContact O-CB 3.17Å; Y6-A10 PolarHBondContact O-N 2.69Å; L7-A10 PolarHBondContact O-N 3.27Å; L8-A10 PolarHBondContact O-N 2.63Å; A10-S13 PolarHBondContact O-N 2.86Å; A10-L14 VanDerWaalsContact O-CB 3.31Å; A10-L14 WeakPolarHBondContact O-CB 3.41Å; A10-L14 PolarHBondContact O-N 3.25Å
11I92.6Very high89.2Confident92 Ų92103.4 Ų103.447%0.47253%0.528SS..Hα-helixtrans-64.4-47.2176.8-67.8169.3000110.4L7 L8 S13 L14 L15L7-I11 WeakPolarHBondContact O-CB 3.17Å; L7-I11 WeakPolarHBondContact O-CG1 3.18Å; L7-I11 PolarHBondContact O-N 3.16Å; L8-I11 PolarHBondContact O-N 2.58Å; I11-S13 PolarHBondContact O-N 2.82Å; I11-L14 PolarHBondContact O-N 3.06Å; I11-L15 HydrophobicContact CG2-CD1 3.83Å; I11-L15 HydrophobicContact CG2-CG 4.28Å; I11-L15 WeakPolarHBondContact O-CB 3.29Å; I11-L15 VanDerWaalsContact O-CG 3.23Å; I11-L15 WeakPolarHBondContact O-CG 3.43Å; I11-L15 PolarHBondContact O-N 3.32Å
12S91.6Very high90Very high64 Ų6498 Ų9845%0.44850%0.503SS..Hα-helixtrans-61.8-42.3178-66.20000112.2L8 I9 L15 A16L8-S12 WeakPolarHBondContact O-CB 3.31Å; L8-S12 PolarHBondContact O-N 2.88Å; L8-S12 PolarHBondContact O-OG 2.9Å; L8-S12 VanDerWaalsContact O-OG 3.05Å; I9-S12 PolarHBondContact O-N 3.15Å; S12-L15 PolarHBondContact O-N 2.92Å; S12-A16 WeakPolarHBondContact O-CB 3.35Å; S12-A16 PolarHBondContact O-N 2.85Å
13S92.7Very high90.1Very high69 Ų6992.3 Ų92.348%0.48348%0.478SS..Hα-helixtrans-64.5-43.4175.9-61.20000111.7I9 A10 I11 A16 Y17I9-S13 VanDerWaalsContact O-CB 3.25Å; I9-S13 WeakPolarHBondContact O-CB 3.46Å; I9-S13 PolarHBondContact O-N 3.39Å; I9-S13 PolarHBondContact O-OG 2.88Å; A10-S13 PolarHBondContact O-N 2.86Å; I11-S13 PolarHBondContact O-N 2.82Å; S13-A16 PolarHBondContact O-N 3.2Å; S13-Y17 WeakPolarHBondContact O-CB 3.12Å; S13-Y17 PolarHBondContact O-N 3.06Å
14L91.3Very high90.2Very high101 Ų10189.3 Ų89.353%0.52946%0.458SS..Hα-helixtrans-62.4-45.2175.6178.462.8000111.1A10 I11 Y17 L18A10-L14 VanDerWaalsContact O-CB 3.31Å; A10-L14 WeakPolarHBondContact O-CB 3.41Å; A10-L14 PolarHBondContact O-N 3.25Å; I11-L14 PolarHBondContact O-N 3.06Å; L14-Y17 PolarHBondContact O-N 3.44Å; L14-L18 HydrophobicContact CD1-CD1 4.21Å; L14-L18 HydrophobicContact CD1-CG 4.19Å; L14-L18 HydrophobicContact CG-CD1 4.1Å; L14-L18 HydrophobicContact CG-CG 4.45Å; L14-L18 WeakPolarHBondContact O-CB 3.46Å; L14-L18 VanDerWaalsContact O-CG 3.26Å; L14-L18 WeakPolarHBondContact O-CG 3.37Å; L14-L18 PolarHBondContact O-N 2.68Å
15L87.2Confident90.4Very high108 Ų10884 Ų8457%0.56543%0.429SS*.Hα-helixtrans-62.6-43.2176.8-71.8173.3000111.5I11 S12 L18 Y19I11-L15 HydrophobicContact CG2-CD1 3.83Å; I11-L15 HydrophobicContact CG2-CG 4.28Å; I11-L15 WeakPolarHBondContact O-CB 3.29Å; I11-L15 VanDerWaalsContact O-CG 3.23Å; I11-L15 WeakPolarHBondContact O-CG 3.43Å; I11-L15 PolarHBondContact O-N 3.32Å; S12-L15 PolarHBondContact O-N 2.92Å; L15-L18 PolarHBondContact O-N 3.15Å; L15-Y19 WeakPolarHBondContact O-CB 3.37Å; L15-Y19 PolarHBondContact O-N 3.05Å
16A87.9Confident90.6Very high60 Ų6080.3 Ų80.350%0.49641%0.41SS..Hα-helixtrans-63.4-42.3176.200000111.9S12 S13 Y19 H20S12-A16 WeakPolarHBondContact O-CB 3.35Å; S12-A16 PolarHBondContact O-N 2.85Å; S13-A16 PolarHBondContact O-N 3.2Å; A16-Y19 PolarHBondContact O-N 3.48Å; A16-H20 VanDerWaalsContact O-CB 3.32Å; A16-H20 WeakPolarHBondContact O-CB 3.35Å; A16-H20 PolarHBondContact O-N 2.67Å
17Y89.9Confident90.6Very high134 Ų13477.6 Ų77.653%0.52541%0.406SS..Hα-helixtrans-63.5-47.4175171.8-105.5000112S13 L14 Y19 H20 R21S13-Y17 WeakPolarHBondContact O-CB 3.12Å; S13-Y17 PolarHBondContact O-N 3.06Å; L14-Y17 PolarHBondContact O-N 3.44Å; Y17-Y19 VanDerWaalsContact C-N 3.32Å; Y17-Y19 PolarHBondContact O-N 3.47Å; Y17-H20 PolarHBondContact O-N 2.95Å; Y17-R21 WeakPolarHBondContact O-CB 3.49Å; Y17-R21 PolarHBondContact O-N 3.19Å
18L85.8Confident90.6Very high71 Ų7179.6 Ų79.637%0.37241%0.408SS..Hα-helixtrans-63.1-40.9177.5-70.9176.8000111.5L14 L15 R21 N22L14-L18 HydrophobicContact CD1-CD1 4.21Å; L14-L18 HydrophobicContact CD1-CG 4.19Å; L14-L18 HydrophobicContact CG-CD1 4.1Å; L14-L18 HydrophobicContact CG-CG 4.45Å; L14-L18 WeakPolarHBondContact O-CB 3.46Å; L14-L18 VanDerWaalsContact O-CG 3.26Å; L14-L18 WeakPolarHBondContact O-CG 3.37Å; L14-L18 PolarHBondContact O-N 2.68Å; L15-L18 PolarHBondContact O-N 3.15Å; L18-R21 PolarHBondContact O-N 2.82Å; L18-N22 WeakPolarHBondContact O-CB 3.28Å; L18-N22 VanDerWaalsContact O-CG 3.26Å; L18-N22 PolarHBondContact O-N 3.31Å
19Y84.8Confident90.7Very high94 Ų9477.7 Ų77.737%0.36939%0.392SS..Hα-helixtrans-60.4-53.6175176-90.8000110.9L15 A16 Y17 R21 N22 F23 P38L15-Y19 WeakPolarHBondContact O-CB 3.37Å; L15-Y19 PolarHBondContact O-N 3.05Å; A16-Y19 PolarHBondContact O-N 3.48Å; Y17-Y19 VanDerWaalsContact C-N 3.32Å; Y17-Y19 PolarHBondContact O-N 3.47Å; Y19-R21 VanDerWaalsContact C-N 3.33Å; Y19-R21 PolarHBondContact O-N 2.83Å; Y19-N22 PolarHBondContact O-N 2.89Å; Y19-F23 AromaticContact CD2-CD2 3.95Å; Y19-F23 HydrophobicContact CD2-CD2 3.95Å; Y19-F23 AromaticContact CD2-CE2 3.77Å; Y19-F23 HydrophobicContact CD2-CE2 3.77Å; Y19-F23 HydrophobicContact CD2-CG 4.48Å; Y19-F23 HydrophobicContact CD2-CZ 4.15Å; Y19-F23 HydrophobicContact CE1-CD1 4.3Å; Y19-F23 HydrophobicContact CE1-CG 4.34Å; Y19-F23 AromaticContact CE2-CD1 3.89Å; Y19-F23 HydrophobicContact CE2-CD1 3.89Å; Y19-F23 AromaticContact CE2-CD2 3.86Å; Y19-F23 HydrophobicContact CE2-CD2 3.86Å; Y19-F23 AromaticContact CE2-CE1 3.64Å; Y19-F23 HydrophobicContact CE2-CE1 3.64Å; Y19-F23 AromaticContact CE2-CE2 3.54Å; Y19-F23 HydrophobicContact CE2-CE2 3.54Å; Y19-F23 HydrophobicContact CE2-CG 4.07Å; Y19-F23 AromaticContact CE2-CZ 3.46Å; Y19-F23 HydrophobicContact CE2-CZ 3.46Å; Y19-F23 VanDerWaalsContact CE2-CZ 3.46Å; Y19-F23 HydrophobicContact CG-CD2 4.42Å; Y19-F23 AromaticContact CZ-CD1 3.63Å; Y19-F23 AromaticContact CZ-CE1 3.72Å; Y19-F23 AromaticContact CZ-CG 3.97Å; Y19-F23 WeakPolarHBondContact O-CB 3.36Å; Y19-F23 WeakPolarHBondContact O-CD2 3.48Å; Y19-F23 PolarHBondContact O-N 3.36Å; Y19-F23 WeakPolarHBondContact OH-CD1 3.31Å; Y19-F23 WeakPolarHBondContact OH-CE1 3.36Å; Y19-P38 HydrophobicContact CE2-CB 4.27Å; Y19-P38 WeakPolarHBondContact OH-CA 3.18Å; Y19-P38 WeakPolarHBondContact OH-CB 2.8Å; Y19-P38 WeakPolarHBondContact OH-CG 3.3Å
20H86.9Confident90.6Very high120 Ų12076 Ų7656%0.55640%0.397SS*.Hα-helixtrans-60.7-42.2178.2-174.383.3000111.8A16 Y17 N22 N24A16-H20 VanDerWaalsContact O-CB 3.32Å; A16-H20 WeakPolarHBondContact O-CB 3.35Å; A16-H20 PolarHBondContact O-N 2.67Å; Y17-H20 PolarHBondContact O-N 2.95Å; H20-N22 PolarHBondContact O-N 2.73Å; H20-N24 PolarHBondContact CE1-ND2 2.86Å; H20-N24 PolarHBondContact ND1-ND2 3.5Å; H20-N24 PolarHBondContact NE2-ND2 2.78Å; H20-N24 WeakPolarHBondContact O-CB 3.49Å; H20-N24 PolarHBondContact O-N 3.48Å; H20-N24 PolarHBondContact O-ND2 3.46Å
21R87.3Confident90.8Very high120 Ų12073.6 Ų73.645%0.45338%0.377SS..Hα-helixtrans-61.1-42.6176.6177.2175.9176.8-177.60.5111.8Y17 L18 Y19 R28Y17-R21 WeakPolarHBondContact O-CB 3.49Å; Y17-R21 PolarHBondContact O-N 3.19Å; L18-R21 PolarHBondContact O-N 2.82Å; Y19-R21 VanDerWaalsContact C-N 3.33Å; Y19-R21 PolarHBondContact O-N 2.83Å; R21-R28 PolarHBondContact O-NH2 3.5Å
22N86.9Confident91Very high58 Ų5870.7 Ų70.731%0.3136%0.364SS..Hα-helixtrans-73.8-44.1-178.8-74.7-11.5000111.4L18 Y19 H20 N24 Y25 Y74L18-N22 WeakPolarHBondContact O-CB 3.28Å; L18-N22 VanDerWaalsContact O-CG 3.26Å; L18-N22 PolarHBondContact O-N 3.31Å; Y19-N22 PolarHBondContact O-N 2.89Å; H20-N22 PolarHBondContact O-N 2.73Å; N22-N24 PolarHBondContact O-N 2.99Å; N22-Y25 WeakPolarHBondContact O-CB 3.45Å; N22-Y25 PolarHBondContact O-N 2.92Å; N22-Y74 WeakPolarHBondContact O-CE1 3.43Å; N22-Y74 PolarHBondContact O-OH 3.45Å
23F88.4Confident91.1Very high17 Ų1769.6 Ų69.68%0.07535%0.352CS..Hα-helixtrans-73.9-16.3-176.2-78.9-127.2000112.8Y19 P36 H37 Y74 H77Y19-F23 AromaticContact CD2-CD2 3.95Å; Y19-F23 HydrophobicContact CD2-CD2 3.95Å; Y19-F23 AromaticContact CD2-CE2 3.77Å; Y19-F23 HydrophobicContact CD2-CE2 3.77Å; Y19-F23 HydrophobicContact CD2-CG 4.48Å; Y19-F23 HydrophobicContact CD2-CZ 4.15Å; Y19-F23 HydrophobicContact CE1-CD1 4.3Å; Y19-F23 HydrophobicContact CE1-CG 4.34Å; Y19-F23 AromaticContact CE2-CD1 3.89Å; Y19-F23 HydrophobicContact CE2-CD1 3.89Å; Y19-F23 AromaticContact CE2-CD2 3.86Å; Y19-F23 HydrophobicContact CE2-CD2 3.86Å; Y19-F23 AromaticContact CE2-CE1 3.64Å; Y19-F23 HydrophobicContact CE2-CE1 3.64Å; Y19-F23 AromaticContact CE2-CE2 3.54Å; Y19-F23 HydrophobicContact CE2-CE2 3.54Å; Y19-F23 HydrophobicContact CE2-CG 4.07Å; Y19-F23 AromaticContact CE2-CZ 3.46Å; Y19-F23 HydrophobicContact CE2-CZ 3.46Å; Y19-F23 VanDerWaalsContact CE2-CZ 3.46Å; Y19-F23 HydrophobicContact CG-CD2 4.42Å; Y19-F23 AromaticContact CZ-CD1 3.63Å; Y19-F23 AromaticContact CZ-CE1 3.72Å; Y19-F23 AromaticContact CZ-CG 3.97Å; Y19-F23 WeakPolarHBondContact O-CB 3.36Å; Y19-F23 WeakPolarHBondContact O-CD2 3.48Å; Y19-F23 PolarHBondContact O-N 3.36Å; Y19-F23 WeakPolarHBondContact OH-CD1 3.31Å; Y19-F23 WeakPolarHBondContact OH-CE1 3.36Å; F23-P36 HydrophobicContact CB-CG 4.03Å; F23-P36 HydrophobicContact CD1-CB 3.67Å; F23-P36 HydrophobicContact CD1-CG 3.3Å; F23-P36 HydrophobicContact CE1-CB 3.66Å; F23-P36 HydrophobicContact CE1-CG 3.87Å; F23-P36 HydrophobicContact CG-CG 3.89Å; F23-H37 WeakPolarHBondContact CE1-O 3.49Å; F23-Y74 VanDerWaalsContact C-OH 3.26Å; F23-Y74 PolarHBondContact O-OH 3.48Å; F23-H77 HydrophobicContact CE2-CB 4.05Å; F23-H77 HydrophobicContact CZ-CB 4.42Å
24N91Very high91.1Very high44 Ų4468.6 Ų68.624%0.23534%0.341CS..THydrogen-bonded Turntrans-97.211.8168.6-78.4-44.4000114.2H20 N22 W26 R28H20-N24 PolarHBondContact CE1-ND2 2.86Å; H20-N24 PolarHBondContact ND1-ND2 3.5Å; H20-N24 PolarHBondContact NE2-ND2 2.78Å; H20-N24 WeakPolarHBondContact O-CB 3.49Å; H20-N24 PolarHBondContact O-N 3.48Å; H20-N24 PolarHBondContact O-ND2 3.46Å; N22-N24 PolarHBondContact O-N 2.99Å; N24-W26 PolarHBondContact O-N 3.47Å; N24-R28 WeakPolarHBondContact O-CG 3.25Å; N24-R28 PolarHBondContact O-N 2.69Å; N24-R28 VanDerWaalsContact O-N 3.13Å; N24-R28 PolarHBondContact O-NE 3.11Å
25Y94.7Very high91.1Very high18 Ų1868.2 Ų68.27%0.07135%0.352CS..THydrogen-bonded Turntrans-55.9-52-178.7176.4-87.6000112.6N22 R29 Y74 P79 E398 T401N22-Y25 WeakPolarHBondContact O-CB 3.45Å; N22-Y25 PolarHBondContact O-N 2.92Å; Y25-R29 VanDerWaalsContact CD2-NH1 3.25Å; Y25-R29 VanDerWaalsContact CZ-CZ 3.44Å; Y25-R29 VanDerWaalsContact CZ-NE 3.3Å; Y25-R29 PolarHBondContact O-NH1 3.42Å; Y25-R29 PolarHBondContact OH-NE 3.15Å; Y25-Y74 WeakPolarHBondContact CB-OH 3.46Å; Y25-Y74 PolarHBondContact N-OH 3.18Å; Y25-P79 HydrophobicContact CD1-CB 3.51Å; Y25-P79 HydrophobicContact CD1-CG 4Å; Y25-P79 HydrophobicContact CD2-CG 4.18Å; Y25-P79 HydrophobicContact CE1-CB 3.99Å; Y25-P79 HydrophobicContact CE1-CG 4.37Å; Y25-P79 HydrophobicContact CG-CB 3.88Å; Y25-P79 HydrophobicContact CG-CG 3.92Å; Y25-E398 WeakPolarHBondContact CE2-OE2 3.31Å; Y25-E398 VanDerWaalsContact CZ-OE2 3.27Å; Y25-E398 VanDerWaalsContact OH-CD 3.27Å; Y25-E398 PolarHBondContact OH-OE2 3.37Å; Y25-T401 PolarHBondContact OH-OG1 2.88Å
26W95.8Very high91.2Very high0 Ų064.1 Ų64.10%033%0.332CS..THydrogen-bonded Turntrans-74.6-36.5-177.7-66.5123.3000112.9N24 R28 R29 G30 V31 H33 F70 G72 F73 Y74 P79 A80 A81 T401N24-W26 PolarHBondContact O-N 3.47Å; W26-R28 VanDerWaalsContact C-N 3.34Å; W26-R28 PolarHBondContact O-N 3.38Å; W26-R29 CarbonylContact O-C 3.42Å; W26-R29 PolarHBondContact O-N 2.96Å; W26-G30 PolarHBondContact O-N 2.89Å; W26-V31 HydrophobicContact CB-CB 4.42Å; W26-V31 HydrophobicContact CD2-CB 4.47Å; W26-V31 HydrophobicContact CD2-CG1 4.49Å; W26-V31 HydrophobicContact CE3-CB 3.7Å; W26-V31 HydrophobicContact CE3-CG1 3.86Å; W26-V31 HydrophobicContact CE3-CG2 3.8Å; W26-V31 HydrophobicContact CZ3-CB 4.4Å; W26-V31 HydrophobicContact CZ3-CG1 4.32Å; W26-V31 HydrophobicContact CZ3-CG2 4.13Å; W26-V31 PolarHBondContact O-N 2.89Å; W26-H33 HydrophobicContact CB-CB 4.21Å; W26-H33 WeakPolarHBondContact CB-ND1 3.47Å; W26-F70 HydrophobicContact CE3-CE2 4.44Å; W26-F70 AromaticContact CH2-CE2 3.99Å; W26-F70 HydrophobicContact CH2-CE2 3.99Å; W26-F70 AromaticContact CZ3-CE2 3.59Å; W26-F70 HydrophobicContact CZ3-CE2 3.59Å; W26-F70 HydrophobicContact CZ3-CZ 4.35Å; W26-G72 VanDerWaalsContact CD1-CA 3.44Å; W26-G72 VanDerWaalsContact CE2-CA 3.41Å; W26-G72 VanDerWaalsContact CG-CA 3.49Å; W26-F73 PolarHBondContact NE1-O 3.28Å; W26-Y74 AromaticContact CD1-CE2 3.41Å; W26-Y74 VanDerWaalsContact CD1-CE2 3.41Å; W26-Y74 AromaticContact CD1-CZ 3.56Å; W26-Y74 HydrophobicContact CG-CE2 4.42Å; W26-Y74 PolarHBondContact N-OH 2.85Å; W26-P79 HydrophobicContact CZ2-CB 4.09Å; W26-A80 WeakPolarHBondContact CZ2-O 3.38Å; W26-A81 HydrophobicContact CH2-CB 4.07Å; W26-T401 HydrophobicContact CH2-CG2 4.09Å; W26-T401 HydrophobicContact CZ2-CG2 4.22Å
27N94Very high91.2Very high102 Ų10263.7 Ų63.755%0.54532%0.32SS..G310 helixtrans-57.7-45.6176.3-170.538.3000112R29 G30 H33N27-R29 PolarHBondContact O-N 3.11Å; N27-R29 VanDerWaalsContact O-N 3.14Å; N27-G30 PolarHBondContact O-N 3.07Å; N27-G30 VanDerWaalsContact O-N 3.12Å; N27-H33 PolarHBondContact N-CE1 2.75Å; N27-H33 VanDerWaalsContact N-CE1 3.28Å
28R93.4Very high90.7Very high137 Ų13760.9 Ų60.952%0.51732%0.318SS..G310 helixtrans-64.4-17.5177.1-71.5-175.9-59.2-155.7-1.3114.5R21 N24 W26R21-R28 PolarHBondContact O-NH2 3.5Å; N24-R28 WeakPolarHBondContact O-CG 3.25Å; N24-R28 PolarHBondContact O-N 2.69Å; N24-R28 VanDerWaalsContact O-N 3.13Å; N24-R28 PolarHBondContact O-NE 3.11Å; W26-R28 VanDerWaalsContact C-N 3.34Å; W26-R28 PolarHBondContact O-N 3.38Å
29R94.2Very high90.3Very high74 Ų7463.6 Ų63.628%0.27933%0.332SS..G310 helixtrans-100.80.2180-71.4167.4179.669.43112.5Y25 W26 N27 V31 E398Y25-R29 VanDerWaalsContact CD2-NH1 3.25Å; Y25-R29 VanDerWaalsContact CZ-CZ 3.44Å; Y25-R29 VanDerWaalsContact CZ-NE 3.3Å; Y25-R29 PolarHBondContact O-NH1 3.42Å; Y25-R29 PolarHBondContact OH-NE 3.15Å; W26-R29 CarbonylContact O-C 3.42Å; W26-R29 PolarHBondContact O-N 2.96Å; N27-R29 PolarHBondContact O-N 3.11Å; N27-R29 VanDerWaalsContact O-N 3.14Å; R29-V31 HydrophobicContact CB-CG2 3.95Å; R29-V31 PolarHBondContact O-N 2.93Å; R29-E398 IonicContact CZ-OE1 3.12Å; R29-E398 IonicContact CZ-OE2 3.29Å; R29-E398 VanDerWaalsContact CZ-OE2 3.29Å; R29-E398 IonicContact NE-OE1 3.55Å; R29-E398 PolarHBondContact NE-OE1 2.9Å; R29-E398 IonicContact NE-OE2 2.75Å; R29-E398 PolarHBondContact NE-OE2 2.59Å; R29-E398 IonicContact NH2-OE1 2.62Å; R29-E398 PolarHBondContact NH2-OE1 3.08Å; R29-E398 IonicContact NH2-OE2 2.7Å; R29-E398 PolarHBondContact NH2-OE2 3.2Å
30G93.8Very high90.1Very high55 Ų5562.1 Ų62.157%0.56733%0.326SS*.THydrogen-bonded Turntrans62.725.1-176.300000113.4W26 N27W26-G30 PolarHBondContact O-N 2.89Å; N27-G30 PolarHBondContact O-N 3.07Å; N27-G30 VanDerWaalsContact O-N 3.12Å
31V96.6Very high90.1Very high7 Ų756.4 Ų56.44%0.04230%0.3CS..  trans-92.4126178.2-179.40000108.8W26 R29 H33 F70 G72 L395W26-V31 HydrophobicContact CB-CB 4.42Å; W26-V31 HydrophobicContact CD2-CB 4.47Å; W26-V31 HydrophobicContact CD2-CG1 4.49Å; W26-V31 HydrophobicContact CE3-CB 3.7Å; W26-V31 HydrophobicContact CE3-CG1 3.86Å; W26-V31 HydrophobicContact CE3-CG2 3.8Å; W26-V31 HydrophobicContact CZ3-CB 4.4Å; W26-V31 HydrophobicContact CZ3-CG1 4.32Å; W26-V31 HydrophobicContact CZ3-CG2 4.13Å; W26-V31 PolarHBondContact O-N 2.89Å; R29-V31 HydrophobicContact CB-CG2 3.95Å; R29-V31 PolarHBondContact O-N 2.93Å; V31-H33 PolarHBondContact O-ND1 2.82Å; V31-F70 HydrophobicContact CG1-CD2 4.16Å; V31-F70 HydrophobicContact CG1-CE2 3.79Å; V31-F70 HydrophobicContact CG2-CE2 4.08Å; V31-F70 HydrophobicContact CG2-CZ 4.26Å; V31-G72 VanDerWaalsContact CG1-N 3.3Å; V31-L395 HydrophobicContact CG2-CD2 4.22Å
32P96.3Very high90.1Very high32 Ų3251.5 Ų51.521%0.20828%0.283CS..  trans-57.4138.8175.4-22.832.3000111.4Y63 F68 V71 G72P32-Y63 HydrophobicContact CB-CD1 4.24Å; P32-Y63 HydrophobicContact CB-CE1 3.91Å; P32-F68 VanDerWaalsContact CD-CE1 3.49Å; P32-F68 HydrophobicContact CG-CD1 4.07Å; P32-F68 HydrophobicContact CG-CD2 3.62Å; P32-F68 HydrophobicContact CG-CE1 4Å; P32-F68 HydrophobicContact CG-CE2 3.54Å; P32-F68 HydrophobicContact CG-CG 3.89Å; P32-F68 HydrophobicContact CG-CZ 3.74Å; P32-V71 HydrophobicContact CB-CG1 4.09Å; P32-V71 VanDerWaalsContact O-CB 3.3Å; P32-V71 WeakPolarHBondContact O-CB 3.5Å; P32-G72 PolarHBondContact O-N 2.92Å
33H95Very high89.7Confident41 Ų4148.9 Ų48.919%0.1927%0.269CS..BIsolated β-bridgetrans-164.3160.1178.460.1-70.7000110.3W26 N27 V31 Y63 G72 Y74W26-H33 HydrophobicContact CB-CB 4.21Å; W26-H33 WeakPolarHBondContact CB-ND1 3.47Å; N27-H33 PolarHBondContact N-CE1 2.75Å; N27-H33 VanDerWaalsContact N-CE1 3.28Å; V31-H33 PolarHBondContact O-ND1 2.82Å; H33-Y63 PolarHBondContact O-OH 2.9Å; H33-G72 WeakPolarHBondContact CB-O 3.28Å; H33-Y74 AromaticContact CD2-CE2 3.99Å
34D93.3Very high89Confident48 Ų4850.2 Ų50.226%0.25728%0.278SS..PPolyproline II helixtrans-79143.1166.6-82-16.7000111.3P36 N42 Y59 K62 Y63D34-P36 VanDerWaalsContact O-CD 3.26Å; D34-P36 WeakPolarHBondContact O-CD 3.42Å; D34-P36 VanDerWaalsContact O-N 3.13Å; D34-N42 VanDerWaalsContact CB-ND2 3.28Å; D34-N42 WeakPolarHBondContact CB-ND2 3.21Å; D34-N42 PolarHBondContact O-ND2 2.69Å; D34-Y59 HydrophobicContact CB-CE2 3.91Å; D34-Y59 PolarHBondContact N-OH 3.24Å; D34-Y59 WeakPolarHBondContact OD2-CE2 3.34Å; D34-K62 IonicContact OD1-NZ 2.75Å; D34-K62 PolarHBondContact OD1-NZ 3.05Å; D34-K62 IonicContact OD2-NZ 3.24Å; D34-Y63 PolarHBondContact N-OH 2.97Å; D34-Y63 PolarHBondContact OD1-OH 3.5Å; D34-Y63 VanDerWaalsContact OD1-OH 3.07Å
35A90.3Very high87.7Confident93 Ų9348.4 Ų48.477%0.76927%0.27SS*.PPolyproline II helixtrans-56.1118.3172.300000110.1
36P89.5Confident86.3Confident21 Ų2151.2 Ų51.214%0.13628%0.283CS..PPolyproline II helixtrans-70.2135.5-176.824.4-33.5000112.6F23 D34 Y74F23-P36 HydrophobicContact CB-CG 4.03Å; F23-P36 HydrophobicContact CD1-CB 3.67Å; F23-P36 HydrophobicContact CD1-CG 3.3Å; F23-P36 HydrophobicContact CE1-CB 3.66Å; F23-P36 HydrophobicContact CE1-CG 3.87Å; F23-P36 HydrophobicContact CG-CG 3.89Å; D34-P36 VanDerWaalsContact O-CD 3.26Å; D34-P36 WeakPolarHBondContact O-CD 3.42Å; D34-P36 VanDerWaalsContact O-N 3.13Å; P36-Y74 HydrophobicContact CB-CD1 4.4Å; P36-Y74 HydrophobicContact CB-CD2 3.52Å; P36-Y74 HydrophobicContact CB-CE2 4.1Å; P36-Y74 HydrophobicContact CB-CG 3.68Å; P36-Y74 HydrophobicContact CG-CD2 3.59Å; P36-Y74 HydrophobicContact CG-CE2 3.61Å; P36-Y74 HydrophobicContact CG-CG 4.06Å
37H87.7Confident84.8Confident51 Ų5159.1 Ų59.124%0.23631%0.313CS..BIsolated β-bridgetrans-68.6140.3170180-76.6000110.6F23 L39 Y40 G41 V44F23-H37 WeakPolarHBondContact CE1-O 3.49Å; H37-L39 VanDerWaalsContact C-N 3.31Å; H37-L39 PolarHBondContact ND1-N 3.35Å; H37-L39 VanDerWaalsContact ND1-N 3.19Å; H37-L39 PolarHBondContact O-N 3.21Å; H37-L39 VanDerWaalsContact O-N 3.07Å; H37-Y40 AromaticContact CE1-CD2 3.81Å; H37-Y40 AromaticContact ND1-CD2 3.73Å; H37-Y40 PolarHBondContact O-N 3.07Å; H37-G41 WeakPolarHBondContact CB-O 3.48Å; H37-G41 PolarHBondContact N-O 2.8Å; H37-G41 WeakPolarHBondContact O-CA 2.93Å; H37-G41 PolarHBondContact O-N 2.69Å; H37-V44 HydrophobicContact CB-CG2 3.36Å
38P79.8Confident83.6Confident75 Ų7561.6 Ų61.649%0.48732%0.319SS..THydrogen-bonded Turntrans-52.9-38.8-171.8-29.333.5000117.1Y19Y19-P38 HydrophobicContact CE2-CB 4.27Å; Y19-P38 WeakPolarHBondContact OH-CA 3.18Å; Y19-P38 WeakPolarHBondContact OH-CB 2.8Å; Y19-P38 WeakPolarHBondContact OH-CG 3.3Å
39L76.9Confident82.6Confident128 Ų12860.5 Ų60.567%0.6732%0.323SS*.THydrogen-bonded Turntrans-98.1-32.5-179.7-63.6175.9000114.7H37H37-L39 VanDerWaalsContact C-N 3.31Å; H37-L39 PolarHBondContact ND1-N 3.35Å; H37-L39 VanDerWaalsContact ND1-N 3.19Å; H37-L39 PolarHBondContact O-N 3.21Å; H37-L39 VanDerWaalsContact O-N 3.07Å
40Y80.2Confident82.1Confident63 Ų6360.7 Ų60.725%0.24732%0.323CS..THydrogen-bonded Turntrans-111-5.1-168-65.4-75.6000112.8H37 N42 M43 R47 L76H37-Y40 AromaticContact CE1-CD2 3.81Å; H37-Y40 AromaticContact ND1-CD2 3.73Å; H37-Y40 PolarHBondContact O-N 3.07Å; Y40-N42 PolarHBondContact O-N 3.47Å; Y40-M43 WeakPolarHBondContact O-CA 3.17Å; Y40-M43 WeakPolarHBondContact O-CB 3.36Å; Y40-M43 WeakPolarHBondContact O-CG 3.38Å; Y40-M43 PolarHBondContact O-N 3.25Å; Y40-R47 HydrophobicContact CD2-CB 4.44Å; Y40-R47 HydrophobicContact CE2-CB 4.22Å; Y40-R47 HydrophobicContact CE2-CG 4.47Å; Y40-L76 HydrophobicContact CD1-CD2 4.43Å
41G87Confident81.7Confident0 Ų058.8 Ų58.80%030%0.301CS..BIsolated β-bridgetrans59.5-130.8-172.400000110.8H37 M43 V44 L76H37-G41 WeakPolarHBondContact CB-O 3.48Å; H37-G41 PolarHBondContact N-O 2.8Å; H37-G41 WeakPolarHBondContact O-CA 2.93Å; H37-G41 PolarHBondContact O-N 2.69Å; G41-M43 VanDerWaalsContact C-N 3.3Å; G41-V44 WeakPolarHBondContact O-CG2 3.48Å; G41-L76 WeakPolarHBondContact CA-O 3.27Å; G41-L76 PolarHBondContact N-O 2.86Å
42N87.4Confident81.3Confident18 Ų1859.7 Ų59.710%0.09631%0.305CS..THydrogen-bonded Turntrans-87.8-0.4172.1-57.1115000112.7D34 Y40 V44 F73 Y74D34-N42 VanDerWaalsContact CB-ND2 3.28Å; D34-N42 WeakPolarHBondContact CB-ND2 3.21Å; D34-N42 PolarHBondContact O-ND2 2.69Å; Y40-N42 PolarHBondContact O-N 3.47Å; N42-V44 PolarHBondContact O-N 2.97Å; N42-F73 HydrophobicContact CB-CD2 3.73Å; N42-F73 HydrophobicContact CB-CE2 3.5Å; N42-F73 HydrophobicContact CB-CG 4.33Å; N42-F73 HydrophobicContact CB-CZ 3.93Å; N42-Y74 PolarHBondContact N-O 3.35Å; N42-Y74 WeakPolarHBondContact OD1-CB 3.48Å; N42-Y74 WeakPolarHBondContact OD1-CD2 3.48Å; N42-Y74 PolarHBondContact OD1-N 3.33Å
43M79.6Confident81Confident3 Ų358.6 Ų58.62%0.01530%0.297CS..G310 helixtrans-78.323.9175.5-46.5-65.1-60.100113Y40 G41 G45 F46 F55 F73 F75Y40-M43 WeakPolarHBondContact O-CA 3.17Å; Y40-M43 WeakPolarHBondContact O-CB 3.36Å; Y40-M43 WeakPolarHBondContact O-CG 3.38Å; Y40-M43 PolarHBondContact O-N 3.25Å; G41-M43 VanDerWaalsContact C-N 3.3Å; M43-G45 PolarHBondContact O-N 2.96Å; M43-F46 HydrophobicContact CB-CD2 3.95Å; M43-F46 HydrophobicContact CE-CD2 3.54Å; M43-F46 HydrophobicContact CE-CE2 3.09Å; M43-F46 HydrophobicContact CE-CZ 4.07Å; M43-F46 WeakPolarHBondContact O-CB 3.49Å; M43-F46 PolarHBondContact O-N 3.25Å; M43-F55 HydrophobicContact CE-CE1 4.16Å; M43-F55 HydrophobicContact CE-CE2 3.86Å; M43-F55 HydrophobicContact CE-CZ 3.33Å; M43-F55 HydrophobicContact SD-CE2 4.06Å; M43-F55 HydrophobicContact SD-CZ 4.15Å; M43-F73 HydrophobicContact CG-CE1 4.47Å; M43-F73 HydrophobicContact SD-CE1 3.39Å; M43-F73 WeakPolarHBondContact SD-CE1 3.41Å; M43-F73 HydrophobicContact SD-CZ 3.34Å; M43-F73 WeakPolarHBondContact SD-CZ 3.41Å; M43-F75 HydrophobicContact CE-CD2 3.91Å; M43-F75 HydrophobicContact CE-CE2 3.57Å; M43-F75 HydrophobicContact CE-CZ 4.33Å; M43-F75 HydrophobicContact CG-CD2 4.25Å; M43-F75 HydrophobicContact CG-CG 4.49Å; M43-F75 HydrophobicContact SD-CD2 3.51Å; M43-F75 VanDerWaalsContact SD-CD2 3.51Å; M43-F75 HydrophobicContact SD-CE2 3.84Å; M43-F75 HydrophobicContact SD-CG 4.24Å
44V72Confident80.7Confident44 Ų4459.9 Ų59.927%0.26731%0.305SS..G310 helixtrans-59.1-24.9-176.9-175.80000112H37 G41 N42 F46 R47 K48H37-V44 HydrophobicContact CB-CG2 3.36Å; G41-V44 WeakPolarHBondContact O-CG2 3.48Å; N42-V44 PolarHBondContact O-N 2.97Å; V44-F46 PolarHBondContact O-N 2.86Å; V44-R47 WeakPolarHBondContact O-CB 3.2Å; V44-R47 PolarHBondContact O-N 3.18Å; V44-K48 PolarHBondContact O-N 3.3Å
45G65.4Low80.5Confident7 Ų758.2 Ų58.27%0.07230%0.296CS..G310 helixtrans-52-35.2170.800000113.5M43 R47 K48 N49 R50M43-G45 PolarHBondContact O-N 2.96Å; G45-R47 VanDerWaalsContact C-N 3.29Å; G45-R47 PolarHBondContact O-N 3Å; G45-K48 CarbonylContact O-C 3.57Å; G45-K48 WeakPolarHBondContact O-CA 3.39Å; G45-K48 PolarHBondContact O-N 3.31Å; G45-N49 PolarHBondContact O-N 3.47Å; G45-R50 WeakPolarHBondContact O-CB 3.41Å; G45-R50 PolarHBondContact O-N 2.69Å
46F65.4Low80.6Confident77 Ų7753.8 Ų53.834%0.33826%0.259SS..G310 helixtrans-62.3-34.4176.6-85.2-95000113M43 V44 K48 N49 M52 F55M43-F46 HydrophobicContact CB-CD2 3.95Å; M43-F46 HydrophobicContact CE-CD2 3.54Å; M43-F46 HydrophobicContact CE-CE2 3.09Å; M43-F46 HydrophobicContact CE-CZ 4.07Å; M43-F46 WeakPolarHBondContact O-CB 3.49Å; M43-F46 PolarHBondContact O-N 3.25Å; V44-F46 PolarHBondContact O-N 2.86Å; F46-K48 VanDerWaalsContact C-N 3.27Å; F46-K48 PolarHBondContact O-N 3.04Å; F46-N49 PolarHBondContact O-N 3.44Å; F46-M52 HydrophobicContact CE2-CE 4.11Å; F46-M52 HydrophobicContact CZ-CE 3.61Å; F46-F55 AromaticContact CD2-CE1 3.85Å; F46-F55 HydrophobicContact CD2-CE1 3.85Å; F46-F55 HydrophobicContact CD2-CZ 4.27Å; F46-F55 AromaticContact CE2-CE1 3.4Å; F46-F55 HydrophobicContact CE2-CE1 3.4Å; F46-F55 AromaticContact CE2-CZ 3.67Å; F46-F55 HydrophobicContact CE2-CZ 3.67Å; F46-F55 HydrophobicContact CZ-CE1 4.36Å
47R63.8Low80.8Confident166 Ų16655.4 Ų55.463%0.62626%0.263SS*.G310 helixtrans-68.1-31.1174.2-179-179.1171.3-179.1-1.3111.6Y40 V44 G45 N49Y40-R47 HydrophobicContact CD2-CB 4.44Å; Y40-R47 HydrophobicContact CE2-CB 4.22Å; Y40-R47 HydrophobicContact CE2-CG 4.47Å; V44-R47 WeakPolarHBondContact O-CB 3.2Å; V44-R47 PolarHBondContact O-N 3.18Å; G45-R47 VanDerWaalsContact C-N 3.29Å; G45-R47 PolarHBondContact O-N 3Å; R47-N49 VanDerWaalsContact C-N 3.29Å
48K67.7Low81.1Confident154 Ų15456.7 Ų56.767%0.6727%0.271SS*.G310 helixtrans-9012.3-179.4-63.3-173179.5-176.40112.9V44 G45 F46 R50V44-K48 PolarHBondContact O-N 3.3Å; G45-K48 CarbonylContact O-C 3.57Å; G45-K48 WeakPolarHBondContact O-CA 3.39Å; G45-K48 PolarHBondContact O-N 3.31Å; F46-K48 VanDerWaalsContact C-N 3.27Å; F46-K48 PolarHBondContact O-N 3.04Å; K48-R50 HydrophobicContact CB-CG 4.08Å; K48-R50 PolarHBondContact O-N 3.46Å
49N73.9Confident81.8Confident113 Ų11353.7 Ų53.760%0.60425%0.251SS*.THydrogen-bonded Turntrans52.935.4-174.8-69.9-25.1000112.8G45 F46 R47 P488G45-N49 PolarHBondContact O-N 3.47Å; F46-N49 PolarHBondContact O-N 3.44Å; R47-N49 VanDerWaalsContact C-N 3.29Å; N49-P488 VanDerWaalsContact C-CB 3.43Å; N49-P488 HydrophobicContact CB-CB 4.33Å; N49-P488 HydrophobicContact CB-CG 3.94Å; N49-P488 VanDerWaalsContact O-CB 3.27Å; N49-P488 WeakPolarHBondContact O-CB 3.21Å
50R81.8Confident82.7Confident78 Ų7847.9 Ų47.929%0.29422%0.22SC..  trans-84.8148.6173.1-65-173.966-173.51.6110.8G45 K48 D54 D58G45-R50 WeakPolarHBondContact O-CB 3.41Å; G45-R50 PolarHBondContact O-N 2.69Å; K48-R50 HydrophobicContact CB-CG 4.08Å; K48-R50 PolarHBondContact O-N 3.46Å; R50-D54 VanDerWaalsContact NH2-CB 3.28Å; R50-D58 IonicContact CZ-OD2 3.67Å; R50-D58 IonicContact NH1-OD2 3.07Å; R50-D58 PolarHBondContact NH1-OD2 3.28Å; R50-D58 IonicContact NH2-OD1 3.4Å; R50-D58 IonicContact NH2-OD2 3.93Å; R50-D58 PolarHBondContact NH2-OD2 3.37Å
51V86.6Confident83.5Confident15 Ų1547.3 Ų47.39%0.09122%0.221CC..  trans-79.4151.7179.8-178.20000109.3H53 D54 F55 Y486 L493V51-H53 HydrophobicContact CG1-CB 4.25Å; V51-H53 PolarHBondContact O-N 3.2Å; V51-D54 PolarHBondContact O-N 2.67Å; V51-F55 WeakPolarHBondContact O-CD1 3.31Å; V51-Y486 WeakPolarHBondContact CG2-O 3.43Å; V51-L493 HydrophobicContact CG1-CD1 4.03Å
52M87.4Confident83.9Confident26 Ų2653.1 Ų53.113%0.12825%0.246CC..Hα-helixtrans-59.9-35.4-177-172.3175-68.300114.1F46 F55 F56 P377 H378F46-M52 HydrophobicContact CE2-CE 4.11Å; F46-M52 HydrophobicContact CZ-CE 3.61Å; M52-F55 HydrophobicContact CB-CE1 3.93Å; M52-F55 HydrophobicContact CB-CZ 4.27Å; M52-F55 HydrophobicContact CG-CE1 3.89Å; M52-F55 HydrophobicContact CG-CZ 3.71Å; M52-F56 HydrophobicContact CG-CD2 3.53Å; M52-F56 HydrophobicContact CG-CE2 3.22Å; M52-F56 HydrophobicContact CG-CZ 4.05Å; M52-F56 WeakPolarHBondContact O-CB 3.45Å; M52-F56 WeakPolarHBondContact O-CD2 3.41Å; M52-F56 PolarHBondContact O-N 3.1Å; M52-F56 HydrophobicContact SD-CD2 4.34Å; M52-F56 HydrophobicContact SD-CE2 3.52Å; M52-F56 VanDerWaalsContact SD-CE2 3.52Å; M52-F56 HydrophobicContact SD-CZ 4.21Å; M52-P377 HydrophobicContact CB-CG 3.99Å; M52-P377 HydrophobicContact CG-CB 4.35Å; M52-P377 HydrophobicContact CG-CG 3.67Å; M52-P377 HydrophobicContact SD-CG 3.51Å; M52-P377 VanDerWaalsContact SD-CG 3.51Å; M52-H378 PolarHBondContact SD-CE1 3.32Å; M52-H378 PolarHBondContact SD-ND1 3.01Å; M52-H378 VanDerWaalsContact SD-ND1 3.37Å
53H90.8Very high84.4Confident10 Ų1053.3 Ų53.35%0.04625%0.246CC..Hα-helixtrans-54.6-54.5173.8-129.9-88.2000111.7V51 F55 F56 Y57 T374 C408 L493V51-H53 HydrophobicContact CG1-CB 4.25Å; V51-H53 PolarHBondContact O-N 3.2Å; H53-F55 PolarHBondContact O-N 3.44Å; H53-F56 PolarHBondContact O-N 2.8Å; H53-Y57 VanDerWaalsContact O-CB 3.25Å; H53-Y57 WeakPolarHBondContact O-CB 3.38Å; H53-Y57 PolarHBondContact O-N 3.03Å; H53-T374 WeakPolarHBondContact NE2-CB 3.49Å; H53-C408 WeakPolarHBondContact CE1-CB 3.43Å; H53-C408 WeakPolarHBondContact ND1-CB 3.49Å; H53-C408 WeakPolarHBondContact NE2-CB 3.05Å; H53-L493 HydrophobicContact CB-CD1 4.43Å
54D89Confident85.1Confident67 Ų6755 Ų5536%0.35825%0.252SS..Hα-helixtrans-65.3-43.9-170.3-47.4-23000112.3R50 V51 Y57 D58R50-D54 VanDerWaalsContact NH2-CB 3.28Å; V51-D54 PolarHBondContact O-N 2.67Å; D54-Y57 PolarHBondContact O-N 2.74Å; D54-D58 VanDerWaalsContact O-CG 3.25Å; D54-D58 PolarHBondContact O-N 2.87Å
55F87.8Confident86.2Confident13 Ų1359.9 Ų59.96%0.05727%0.27CS..Hα-helixtrans-76.9-30.6-176.378-105.5000112.2M43 F46 V51 M52 H53 Y59 F73M43-F55 HydrophobicContact CE-CE1 4.16Å; M43-F55 HydrophobicContact CE-CE2 3.86Å; M43-F55 HydrophobicContact CE-CZ 3.33Å; M43-F55 HydrophobicContact SD-CE2 4.06Å; M43-F55 HydrophobicContact SD-CZ 4.15Å; F46-F55 AromaticContact CD2-CE1 3.85Å; F46-F55 HydrophobicContact CD2-CE1 3.85Å; F46-F55 HydrophobicContact CD2-CZ 4.27Å; F46-F55 AromaticContact CE2-CE1 3.4Å; F46-F55 HydrophobicContact CE2-CE1 3.4Å; F46-F55 AromaticContact CE2-CZ 3.67Å; F46-F55 HydrophobicContact CE2-CZ 3.67Å; F46-F55 HydrophobicContact CZ-CE1 4.36Å; V51-F55 WeakPolarHBondContact O-CD1 3.31Å; M52-F55 HydrophobicContact CB-CE1 3.93Å; M52-F55 HydrophobicContact CB-CZ 4.27Å; M52-F55 HydrophobicContact CG-CE1 3.89Å; M52-F55 HydrophobicContact CG-CZ 3.71Å; H53-F55 PolarHBondContact O-N 3.44Å; F55-Y59 VanDerWaalsContact O-CB 3.27Å; F55-Y59 WeakPolarHBondContact O-CB 3.44Å; F55-Y59 PolarHBondContact O-N 2.92Å; F55-F73 HydrophobicContact CE2-CZ 4.17Å
56F93Very high87.5Confident0 Ų061.7 Ų61.70%028%0.281CS..Hα-helixtrans-69.1-38170.9-75.4-32.4000111.6M52 H53 Y59 Y60 F73 F82 H378 I404 P406M52-F56 HydrophobicContact CG-CD2 3.53Å; M52-F56 HydrophobicContact CG-CE2 3.22Å; M52-F56 HydrophobicContact CG-CZ 4.05Å; M52-F56 WeakPolarHBondContact O-CB 3.45Å; M52-F56 WeakPolarHBondContact O-CD2 3.41Å; M52-F56 PolarHBondContact O-N 3.1Å; M52-F56 HydrophobicContact SD-CD2 4.34Å; M52-F56 HydrophobicContact SD-CE2 3.52Å; M52-F56 VanDerWaalsContact SD-CE2 3.52Å; M52-F56 HydrophobicContact SD-CZ 4.21Å; H53-F56 PolarHBondContact O-N 2.8Å; F56-Y59 PolarHBondContact O-N 3.49Å; F56-Y60 WeakPolarHBondContact O-CB 3.28Å; F56-Y60 PolarHBondContact O-N 3.46Å; F56-F73 HydrophobicContact CE1-CE1 4.35Å; F56-F73 HydrophobicContact CE1-CE2 4.39Å; F56-F73 AromaticContact CE1-CZ 3.89Å; F56-F73 HydrophobicContact CE1-CZ 3.89Å; F56-F82 HydrophobicContact CB-CE2 4.41Å; F56-F82 HydrophobicContact CB-CZ 4.39Å; F56-F82 HydrophobicContact CD1-CD2 4.42Å; F56-F82 AromaticContact CD1-CE2 3.5Å; F56-F82 HydrophobicContact CD1-CE2 3.5Å; F56-F82 VanDerWaalsContact CD1-CE2 3.5Å; F56-F82 HydrophobicContact CD1-CZ 4.25Å; F56-F82 AromaticContact CE1-CE2 3.97Å; F56-F82 HydrophobicContact CE1-CE2 3.97Å; F56-F82 HydrophobicContact CG-CE2 4.15Å; F56-H378 HydrophobicContact CD2-CB 4.14Å; F56-H378 HydrophobicContact CE2-CB 3.71Å; F56-H378 AromaticContact CE2-CG 3.47Å; F56-H378 VanDerWaalsContact CE2-CG 3.47Å; F56-H378 AromaticContact CE2-ND1 3.4Å; F56-H378 WeakPolarHBondContact CE2-ND1 3.22Å; F56-H378 HydrophobicContact CZ-CB 4.37Å; F56-H378 AromaticContact CZ-CG 3.96Å; F56-I404 HydrophobicContact CE1-CG2 4.22Å; F56-I404 HydrophobicContact CZ-CG2 4.19Å; F56-P406 HydrophobicContact CB-CB 4.45Å
57Y93.6Very high88.9Confident56 Ų5661.2 Ų61.222%0.2230%0.297CS..Hα-helixtrans-61.4-49.4173.9-177.6-112.4000112.1H53 D54 Y59 Y60 N61 A409 R412H53-Y57 VanDerWaalsContact O-CB 3.25Å; H53-Y57 WeakPolarHBondContact O-CB 3.38Å; H53-Y57 PolarHBondContact O-N 3.03Å; D54-Y57 PolarHBondContact O-N 2.74Å; Y57-Y59 VanDerWaalsContact C-N 3.34Å; Y57-Y59 PolarHBondContact O-N 2.82Å; Y57-Y60 PolarHBondContact O-N 3.43Å; Y57-N61 WeakPolarHBondContact CE1-ND2 3.1Å; Y57-N61 VanDerWaalsContact CE2-ND2 3.27Å; Y57-N61 WeakPolarHBondContact CE2-ND2 3.18Å; Y57-N61 WeakPolarHBondContact O-CB 3.48Å; Y57-N61 PolarHBondContact O-N 3.39Å; Y57-N61 PolarHBondContact OH-ND2 3.46Å; Y57-A409 HydrophobicContact CD2-CB 4.28Å; Y57-R412 HydrophobicContact CD2-CB 3.91Å; Y57-R412 HydrophobicContact CE2-CB 3.44Å; Y57-R412 VanDerWaalsContact CE2-CB 3.44Å; Y57-R412 WeakPolarHBondContact CE2-O 3.29Å; Y57-R412 PolarHBondContact OH-O 2.64Å
58D93.4Very high90.4Very high77 Ų7756.7 Ų56.741%0.41228%0.282SS..Hα-helixtrans-59.3-45.2176-72.1-4.6000111.9R50 D54 N61 K62R50-D58 IonicContact CZ-OD2 3.67Å; R50-D58 IonicContact NH1-OD2 3.07Å; R50-D58 PolarHBondContact NH1-OD2 3.28Å; R50-D58 IonicContact NH2-OD1 3.4Å; R50-D58 IonicContact NH2-OD2 3.93Å; R50-D58 PolarHBondContact NH2-OD2 3.37Å; D54-D58 VanDerWaalsContact O-CG 3.25Å; D54-D58 PolarHBondContact O-N 2.87Å; D58-N61 PolarHBondContact O-N 2.98Å; D58-K62 WeakPolarHBondContact O-CB 3.46Å; D58-K62 PolarHBondContact O-N 3.28Å
59Y94.8Very high91.8Very high13 Ų1349.5 Ų49.55%0.05125%0.252CS..Hα-helixtrans-63.6-43.9-179.9-157.9-98.1000111.1D34 F55 F56 Y57 Y63 V71 G72 F73 F82D34-Y59 HydrophobicContact CB-CE2 3.91Å; D34-Y59 PolarHBondContact N-OH 3.24Å; D34-Y59 WeakPolarHBondContact OD2-CE2 3.34Å; F55-Y59 VanDerWaalsContact O-CB 3.27Å; F55-Y59 WeakPolarHBondContact O-CB 3.44Å; F55-Y59 PolarHBondContact O-N 2.92Å; F56-Y59 PolarHBondContact O-N 3.49Å; Y57-Y59 VanDerWaalsContact C-N 3.34Å; Y57-Y59 PolarHBondContact O-N 2.82Å; Y59-Y63 HydrophobicContact CD1-CD2 4.13Å; Y59-Y63 HydrophobicContact CD1-CE2 4.43Å; Y59-Y63 HydrophobicContact CD2-CE2 4.33Å; Y59-Y63 AromaticContact CE1-CD2 3.91Å; Y59-Y63 HydrophobicContact CE1-CD2 3.91Å; Y59-Y63 AromaticContact CE1-CE2 3.94Å; Y59-Y63 HydrophobicContact CE1-CE2 3.94Å; Y59-Y63 HydrophobicContact CE2-CD2 4.45Å; Y59-Y63 AromaticContact CE2-CE2 3.83Å; Y59-Y63 HydrophobicContact CE2-CE2 3.83Å; Y59-Y63 AromaticContact CZ-CE2 3.6Å; Y59-Y63 VanDerWaalsContact O-CD2 3.31Å; Y59-Y63 WeakPolarHBondContact O-CD2 3.47Å; Y59-Y63 PolarHBondContact O-N 2.9Å; Y59-V71 HydrophobicContact CD1-CG2 4.33Å; Y59-V71 HydrophobicContact CE1-CG2 3.69Å; Y59-G72 PolarHBondContact OH-O 3.23Å; Y59-F73 AromaticContact CD1-CD2 3.93Å; Y59-F73 HydrophobicContact CD1-CD2 3.93Å; Y59-F73 HydrophobicContact CD1-CE2 4.42Å; Y59-F73 HydrophobicContact CD2-CD2 4.39Å; Y59-F73 HydrophobicContact CD2-CE2 4.43Å; Y59-F73 HydrophobicContact CE1-CB 4.4Å; Y59-F73 AromaticContact CE1-CD2 3.68Å; Y59-F73 HydrophobicContact CE1-CD2 3.68Å; Y59-F73 HydrophobicContact CE2-CD2 4.17Å; Y59-F73 HydrophobicContact CG-CD2 4.27Å; Y59-F73 HydrophobicContact CG-CE2 4.37Å; Y59-F73 AromaticContact CZ-CD2 3.82Å; Y59-F82 AromaticContact CD1-CD1 3.81Å; Y59-F82 HydrophobicContact CD1-CD1 3.81Å; Y59-F82 HydrophobicContact CD1-CD2 4.28Å; Y59-F82 AromaticContact CD1-CE1 3.93Å; Y59-F82 HydrophobicContact CD1-CE1 3.93Å; Y59-F82 HydrophobicContact CD1-CE2 4.4Å; Y59-F82 AromaticContact CD1-CG 3.98Å; Y59-F82 HydrophobicContact CD1-CG 3.98Å; Y59-F82 HydrophobicContact CD1-CZ 4.21Å; Y59-F82 HydrophobicContact CE1-CB 4.36Å; Y59-F82 HydrophobicContact CE1-CD1 4.28Å; Y59-F82 HydrophobicContact CE1-CG 4.23Å
60Y96.8Very high93Very high6 Ų644.1 Ų44.12%0.02422%0.223CC..Hα-helixtrans-60.1-53.5175.1176.6-103000111.5F56 Y57 K62 Y63 R64 F82 V84 P406 A409 Y410 D413F56-Y60 WeakPolarHBondContact O-CB 3.28Å; F56-Y60 PolarHBondContact O-N 3.46Å; Y57-Y60 PolarHBondContact O-N 3.43Å; Y60-K62 PolarHBondContact O-N 2.8Å; Y60-Y63 CarbonylContact O-C 3.44Å; Y60-Y63 PolarHBondContact O-N 3.49Å; Y60-R64 HydrophobicContact CD1-CB 4.22Å; Y60-R64 HydrophobicContact CD2-CB 4.28Å; Y60-R64 HydrophobicContact CE1-CB 3.82Å; Y60-R64 HydrophobicContact CE1-CG 4.16Å; Y60-R64 HydrophobicContact CE2-CB 3.85Å; Y60-R64 HydrophobicContact CG-CB 4.44Å; Y60-R64 WeakPolarHBondContact O-CB 3.44Å; Y60-R64 PolarHBondContact O-N 2.99Å; Y60-F82 HydrophobicContact CD2-CE1 4.36Å; Y60-V84 HydrophobicContact CD2-CB 4.27Å; Y60-V84 HydrophobicContact CD2-CG1 4.14Å; Y60-V84 HydrophobicContact CE2-CB 4.11Å; Y60-V84 HydrophobicContact CE2-CG1 4.48Å; Y60-V84 WeakPolarHBondContact CE2-O 3.37Å; Y60-P406 HydrophobicContact CD2-CG 4.03Å; Y60-A409 VanDerWaalsContact CB-CB 3.5Å; Y60-A409 HydrophobicContact CD1-CB 3.64Å; Y60-A409 HydrophobicContact CD2-CB 4.26Å; Y60-A409 HydrophobicContact CE1-CB 4.44Å; Y60-A409 HydrophobicContact CG-CB 3.53Å; Y60-Y410 HydrophobicContact CD2-CD1 4.35Å; Y60-Y410 HydrophobicContact CD2-CE1 4.11Å; Y60-Y410 AromaticContact CE2-CD1 3.76Å; Y60-Y410 HydrophobicContact CE2-CD1 3.76Å; Y60-Y410 AromaticContact CE2-CE1 3.53Å; Y60-Y410 HydrophobicContact CE2-CE1 3.53Å; Y60-Y410 AromaticContact CZ-CD1 3.93Å; Y60-D413 HydrophobicContact CE1-CB 4.05Å; Y60-D413 PolarHBondContact OH-OD2 3.36Å
61N96.1Very high93.8Very high50 Ų5040.4 Ų40.427%0.26721%0.209SC..Hα-helixtrans-61.2-32.6-177.8-80.5-26000113.4Y57 D58 Y63 R64Y57-N61 WeakPolarHBondContact CE1-ND2 3.1Å; Y57-N61 VanDerWaalsContact CE2-ND2 3.27Å; Y57-N61 WeakPolarHBondContact CE2-ND2 3.18Å; Y57-N61 WeakPolarHBondContact O-CB 3.48Å; Y57-N61 PolarHBondContact O-N 3.39Å; Y57-N61 PolarHBondContact OH-ND2 3.46Å; D58-N61 PolarHBondContact O-N 2.98Å; N61-Y63 VanDerWaalsContact C-N 3.26Å; N61-Y63 PolarHBondContact O-N 3.38Å; N61-R64 PolarHBondContact OD1-NH1 3.49Å
62K96.1Very high94.3Very high123 Ų12339.7 Ų39.754%0.53520%0.204SC..Hα-helixtrans-61.7-34.6174-179.2174.6179.61750112.9D34 D58 Y60D34-K62 IonicContact OD1-NZ 2.75Å; D34-K62 PolarHBondContact OD1-NZ 3.05Å; D34-K62 IonicContact OD2-NZ 3.24Å; D58-K62 WeakPolarHBondContact O-CB 3.46Å; D58-K62 PolarHBondContact O-N 3.28Å; Y60-K62 PolarHBondContact O-N 2.8Å
63Y96.9Very high94.7Very high22 Ų2238.4 Ų38.49%0.08620%0.198CC..Hα-helixtrans-115.4-13.3-169.9-69.9-67.8000115P32 H33 D34 Y59 Y60 N61 K65 S66 V71P32-Y63 HydrophobicContact CB-CD1 4.24Å; P32-Y63 HydrophobicContact CB-CE1 3.91Å; H33-Y63 PolarHBondContact O-OH 2.9Å; D34-Y63 PolarHBondContact N-OH 2.97Å; D34-Y63 PolarHBondContact OD1-OH 3.5Å; D34-Y63 VanDerWaalsContact OD1-OH 3.07Å; Y59-Y63 HydrophobicContact CD1-CD2 4.13Å; Y59-Y63 HydrophobicContact CD1-CE2 4.43Å; Y59-Y63 HydrophobicContact CD2-CE2 4.33Å; Y59-Y63 AromaticContact CE1-CD2 3.91Å; Y59-Y63 HydrophobicContact CE1-CD2 3.91Å; Y59-Y63 AromaticContact CE1-CE2 3.94Å; Y59-Y63 HydrophobicContact CE1-CE2 3.94Å; Y59-Y63 HydrophobicContact CE2-CD2 4.45Å; Y59-Y63 AromaticContact CE2-CE2 3.83Å; Y59-Y63 HydrophobicContact CE2-CE2 3.83Å; Y59-Y63 AromaticContact CZ-CE2 3.6Å; Y59-Y63 VanDerWaalsContact O-CD2 3.31Å; Y59-Y63 WeakPolarHBondContact O-CD2 3.47Å; Y59-Y63 PolarHBondContact O-N 2.9Å; Y60-Y63 CarbonylContact O-C 3.44Å; Y60-Y63 PolarHBondContact O-N 3.49Å; N61-Y63 VanDerWaalsContact C-N 3.26Å; N61-Y63 PolarHBondContact O-N 3.38Å; Y63-K65 PolarHBondContact O-N 2.96Å; Y63-S66 WeakPolarHBondContact O-CB 3.27Å; Y63-S66 PolarHBondContact O-N 3.29Å; Y63-S66 PolarHBondContact O-OG 2.87Å; Y63-V71 HydrophobicContact CD1-CB 4.49Å; Y63-V71 HydrophobicContact CD1-CG1 3.79Å; Y63-V71 HydrophobicContact CD2-CB 4.44Å; Y63-V71 HydrophobicContact CD2-CG1 4.45Å; Y63-V71 HydrophobicContact CD2-CG2 3.92Å; Y63-V71 HydrophobicContact CG-CB 4.22Å; Y63-V71 HydrophobicContact CG-CG1 3.75Å; Y63-V71 HydrophobicContact CG-CG2 3.97Å
64R95.2Very high94.7Very high38 Ų3838 Ų3814%0.14320%0.196CC..THydrogen-bonded Turntrans-59.2-27.1-174.376.1176.4-143.4-127.5-4.1113.5Y60 N61 D413 E414 D415Y60-R64 HydrophobicContact CD1-CB 4.22Å; Y60-R64 HydrophobicContact CD2-CB 4.28Å; Y60-R64 HydrophobicContact CE1-CB 3.82Å; Y60-R64 HydrophobicContact CE1-CG 4.16Å; Y60-R64 HydrophobicContact CE2-CB 3.85Å; Y60-R64 HydrophobicContact CG-CB 4.44Å; Y60-R64 WeakPolarHBondContact O-CB 3.44Å; Y60-R64 PolarHBondContact O-N 2.99Å; N61-R64 PolarHBondContact OD1-NH1 3.49Å; R64-D413 IonicContact CZ-OD1 2.64Å; R64-D413 IonicContact NE-OD1 3.85Å; R64-D413 PolarHBondContact NE-OD1 3.31Å; R64-D413 IonicContact NE-OD2 2.64Å; R64-D413 IonicContact NH1-OD1 2.78Å; R64-D413 PolarHBondContact NH1-OD1 3.42Å; R64-D413 IonicContact NH2-OD1 2.71Å; R64-D413 PolarHBondContact NH2-OD1 3.21Å; R64-E414 IonicContact CZ-OE1 3.53Å; R64-E414 IonicContact NH1-OE1 3.56Å; R64-E414 IonicContact NH2-OE1 2.81Å; R64-E414 PolarHBondContact NH2-OE1 3.42Å; R64-D415 IonicContact CZ-OD2 3.72Å; R64-D415 IonicContact NE-OD2 3.17Å; R64-D415 PolarHBondContact NE-OD2 3.35Å; R64-D415 IonicContact NH2-OD1 2.65Å; R64-D415 IonicContact NH2-OD2 3.76Å; R64-D415 PolarHBondContact NH2-OD2 2.95Å
65K94.3Very high94.6Very high147 Ų14737.4 Ų37.464%0.63919%0.191SC*.THydrogen-bonded Turntrans-98.915176-57.8-172.5178174.10113.6Y63 G67 E414 D415Y63-K65 PolarHBondContact O-N 2.96Å; K65-G67 VanDerWaalsContact C-N 3.3Å; K65-G67 PolarHBondContact O-N 3.25Å; K65-E414 IonicContact NZ-OE1 3.77Å; K65-D415 WeakPolarHBondContact CE-OD2 3.38Å; K65-D415 IonicContact NZ-OD2 2.64Å
66S94.1Very high94.4Very high45 Ų4537.4 Ų37.432%0.31519%0.191SC..SBendtrans-79.1-10-177.577.50000114.2Y63 F68Y63-S66 WeakPolarHBondContact O-CB 3.27Å; Y63-S66 PolarHBondContact O-N 3.29Å; Y63-S66 PolarHBondContact O-OG 2.87Å; S66-F68 WeakPolarHBondContact O-CD2 3.47Å; S66-F68 PolarHBondContact O-N 2.94Å; S66-F68 PolarHBondContact OG-N 3.42Å
67G93.4Very high93.9Very high66 Ų6639.3 Ų39.368%0.6820%0.2SC*.SBendtrans75.47.6-174.900000114.6K65K65-G67 VanDerWaalsContact C-N 3.3Å; K65-G67 PolarHBondContact O-N 3.25Å
68F96.8Very high93.6Very high71 Ų7139.3 Ų39.331%0.31120%0.201SC..  trans-100.6140172.8-73.4-104.5000109.2P32 S66 F70 V84 L395P32-F68 VanDerWaalsContact CD-CE1 3.49Å; P32-F68 HydrophobicContact CG-CD1 4.07Å; P32-F68 HydrophobicContact CG-CD2 3.62Å; P32-F68 HydrophobicContact CG-CE1 4Å; P32-F68 HydrophobicContact CG-CE2 3.54Å; P32-F68 HydrophobicContact CG-CG 3.89Å; P32-F68 HydrophobicContact CG-CZ 3.74Å; S66-F68 WeakPolarHBondContact O-CD2 3.47Å; S66-F68 PolarHBondContact O-N 2.94Å; S66-F68 PolarHBondContact OG-N 3.42Å; F68-F70 VanDerWaalsContact C-N 3.3Å; F68-F70 WeakPolarHBondContact CB-O 3.38Å; F68-F70 PolarHBondContact O-N 2.98Å; F68-V84 WeakPolarHBondContact O-CG2 3.49Å; F68-L395 HydrophobicContact CD1-CD1 3.87Å; F68-L395 HydrophobicContact CD1-CD2 4.18Å; F68-L395 HydrophobicContact CE1-CD1 4.5Å; F68-L395 HydrophobicContact CE1-CD2 4.19Å
69P97.1Very high93.6Very high3 Ų336.9 Ų36.92%0.01919%0.19CC..SBendtrans-74.8-22.1179.331.4-37000112.8V84 D85 L88 V389 L395P69-V84 WeakPolarHBondContact O-CG2 3.4Å; P69-V84 PolarHBondContact O-N 2.94Å; P69-D85 HydrophobicContact CB-CB 3.98Å; P69-D85 PolarHBondContact O-N 3.36Å; P69-L88 HydrophobicContact CB-CB 4.31Å; P69-L88 HydrophobicContact CB-CD2 3.82Å; P69-L88 HydrophobicContact CG-CD2 4.35Å; P69-V389 HydrophobicContact CB-CG1 4.2Å; P69-V389 HydrophobicContact CG-CG1 3.73Å; P69-L395 VanDerWaalsContact CD-CD1 3.47Å; P69-L395 HydrophobicContact CG-CD1 3.78Å
70F98.2Very high93.7Very high0 Ų036.3 Ų36.30%019%0.188CC..EExtended strand (participates in β ladder)trans-146.6158.4169.574.4-92.3000110.4W26 V31 F68 A81 F82 I83 L88 V389 L395 I397W26-F70 HydrophobicContact CE3-CE2 4.44Å; W26-F70 AromaticContact CH2-CE2 3.99Å; W26-F70 HydrophobicContact CH2-CE2 3.99Å; W26-F70 AromaticContact CZ3-CE2 3.59Å; W26-F70 HydrophobicContact CZ3-CE2 3.59Å; W26-F70 HydrophobicContact CZ3-CZ 4.35Å; V31-F70 HydrophobicContact CG1-CD2 4.16Å; V31-F70 HydrophobicContact CG1-CE2 3.79Å; V31-F70 HydrophobicContact CG2-CE2 4.08Å; V31-F70 HydrophobicContact CG2-CZ 4.26Å; F68-F70 VanDerWaalsContact C-N 3.3Å; F68-F70 WeakPolarHBondContact CB-O 3.38Å; F68-F70 PolarHBondContact O-N 2.98Å; F70-A81 HydrophobicContact CD2-CB 3.82Å; F70-A81 HydrophobicContact CE2-CB 4.24Å; F70-A81 HydrophobicContact CG-CB 4.31Å; F70-F82 CarbonylContact C-O 3.04Å; F70-F82 VanDerWaalsContact CA-O 3.28Å; F70-F82 WeakPolarHBondContact CA-O 3.44Å; F70-F82 WeakPolarHBondContact CB-O 3.29Å; F70-I83 HydrophobicContact CB-CD1 3.69Å; F70-I83 HydrophobicContact CG-CD1 4.49Å; F70-L88 HydrophobicContact CB-CD2 4.13Å; F70-L88 HydrophobicContact CD1-CD2 3.95Å; F70-V389 HydrophobicContact CD1-CG2 3.97Å; F70-V389 HydrophobicContact CE1-CG2 3.67Å; F70-L395 HydrophobicContact CE1-CB 3.88Å; F70-L395 HydrophobicContact CE1-CD1 4.49Å; F70-L395 HydrophobicContact CZ-CB 4.31Å; F70-I397 HydrophobicContact CD1-CD1 4.36Å; F70-I397 HydrophobicContact CD1-CG1 4.24Å; F70-I397 HydrophobicContact CE1-CD1 4.44Å; F70-I397 HydrophobicContact CE1-CG1 3.85Å; F70-I397 HydrophobicContact CZ-CG1 4.08Å
71V98Very high93.7Very high0 Ų036 Ų360%019%0.186CC..EExtended strand (participates in β ladder)trans-121.9159.1173.1-68.60000110.7P32 Y59 Y63 F82 V84P32-V71 HydrophobicContact CB-CG1 4.09Å; P32-V71 VanDerWaalsContact O-CB 3.3Å; P32-V71 WeakPolarHBondContact O-CB 3.5Å; Y59-V71 HydrophobicContact CD1-CG2 4.33Å; Y59-V71 HydrophobicContact CE1-CG2 3.69Å; Y63-V71 HydrophobicContact CD1-CB 4.49Å; Y63-V71 HydrophobicContact CD1-CG1 3.79Å; Y63-V71 HydrophobicContact CD2-CB 4.44Å; Y63-V71 HydrophobicContact CD2-CG1 4.45Å; Y63-V71 HydrophobicContact CD2-CG2 3.92Å; Y63-V71 HydrophobicContact CG-CB 4.22Å; Y63-V71 HydrophobicContact CG-CG1 3.75Å; Y63-V71 HydrophobicContact CG-CG2 3.97Å; V71-F82 HydrophobicContact CG2-CB 4.15Å; V71-F82 HydrophobicContact CG2-CD1 4.07Å; V71-F82 PolarHBondContact N-O 3.46Å; V71-F82 PolarHBondContact O-N 3.44Å; V71-V84 HydrophobicContact CG2-CG1 3.98Å
72G97.1Very high93.8Very high0 Ų033.7 Ų33.70%017%0.174CC..EExtended strand (participates in β ladder)trans-73.7139.3178.400000110.3W26 V31 P32 H33 Y59W26-G72 VanDerWaalsContact CD1-CA 3.44Å; W26-G72 VanDerWaalsContact CE2-CA 3.41Å; W26-G72 VanDerWaalsContact CG-CA 3.49Å; V31-G72 VanDerWaalsContact CG1-N 3.3Å; P32-G72 PolarHBondContact O-N 2.92Å; H33-G72 WeakPolarHBondContact CB-O 3.28Å; Y59-G72 PolarHBondContact OH-O 3.23Å
73F95.5Very high94Very high0 Ų027.8 Ų27.80%015%0.148CC..EExtended strand (participates in β ladder)trans-137.8155.1174.7-173.5-92.8000109.5W26 N42 M43 F55 F56 Y59 F75 P79 A80 F82 I404W26-F73 PolarHBondContact NE1-O 3.28Å; N42-F73 HydrophobicContact CB-CD2 3.73Å; N42-F73 HydrophobicContact CB-CE2 3.5Å; N42-F73 HydrophobicContact CB-CG 4.33Å; N42-F73 HydrophobicContact CB-CZ 3.93Å; M43-F73 HydrophobicContact CG-CE1 4.47Å; M43-F73 HydrophobicContact SD-CE1 3.39Å; M43-F73 WeakPolarHBondContact SD-CE1 3.41Å; M43-F73 HydrophobicContact SD-CZ 3.34Å; M43-F73 WeakPolarHBondContact SD-CZ 3.41Å; F55-F73 HydrophobicContact CE2-CZ 4.17Å; F56-F73 HydrophobicContact CE1-CE1 4.35Å; F56-F73 HydrophobicContact CE1-CE2 4.39Å; F56-F73 AromaticContact CE1-CZ 3.89Å; F56-F73 HydrophobicContact CE1-CZ 3.89Å; Y59-F73 AromaticContact CD1-CD2 3.93Å; Y59-F73 HydrophobicContact CD1-CD2 3.93Å; Y59-F73 HydrophobicContact CD1-CE2 4.42Å; Y59-F73 HydrophobicContact CD2-CD2 4.39Å; Y59-F73 HydrophobicContact CD2-CE2 4.43Å; Y59-F73 HydrophobicContact CE1-CB 4.4Å; Y59-F73 AromaticContact CE1-CD2 3.68Å; Y59-F73 HydrophobicContact CE1-CD2 3.68Å; Y59-F73 HydrophobicContact CE2-CD2 4.17Å; Y59-F73 HydrophobicContact CG-CD2 4.27Å; Y59-F73 HydrophobicContact CG-CE2 4.37Å; Y59-F73 AromaticContact CZ-CD2 3.82Å; F73-F75 HydrophobicContact CE1-CB 4.33Å; F73-F75 HydrophobicContact CE1-CD2 4.43Å; F73-P79 CarbonylContact O-C 3.58Å; F73-P79 WeakPolarHBondContact O-CA 3.28Å; F73-A80 WeakPolarHBondContact CA-O 3.28Å; F73-A80 WeakPolarHBondContact CB-O 3.4Å; F73-A80 HydrophobicContact CD1-CB 4.49Å; F73-A80 PolarHBondContact N-O 3.47Å; F73-A80 PolarHBondContact O-N 2.67Å; F73-A80 VanDerWaalsContact O-O 3.07Å; F73-F82 HydrophobicContact CB-CB 3.76Å; F73-F82 HydrophobicContact CD2-CD2 4.24Å; F73-F82 HydrophobicContact CG-CB 4.43Å; F73-F82 HydrophobicContact CG-CD2 4.39Å; F73-I404 HydrophobicContact CD1-CD1 3.56Å; F73-I404 HydrophobicContact CE1-CD1 3.85Å; F73-I404 HydrophobicContact CG-CD1 4.36Å
74Y92.1Very high94Very high0 Ų027.1 Ų27.10%015%0.146CC..EExtended strand (participates in β ladder)trans-122.1103.4176.7-72.9-84.7000109.5N22 F23 Y25 W26 H33 P36 N42 L76 K78 P79N22-Y74 WeakPolarHBondContact O-CE1 3.43Å; N22-Y74 PolarHBondContact O-OH 3.45Å; F23-Y74 VanDerWaalsContact C-OH 3.26Å; F23-Y74 PolarHBondContact O-OH 3.48Å; Y25-Y74 WeakPolarHBondContact CB-OH 3.46Å; Y25-Y74 PolarHBondContact N-OH 3.18Å; W26-Y74 AromaticContact CD1-CE2 3.41Å; W26-Y74 VanDerWaalsContact CD1-CE2 3.41Å; W26-Y74 AromaticContact CD1-CZ 3.56Å; W26-Y74 HydrophobicContact CG-CE2 4.42Å; W26-Y74 PolarHBondContact N-OH 2.85Å; H33-Y74 AromaticContact CD2-CE2 3.99Å; P36-Y74 HydrophobicContact CB-CD1 4.4Å; P36-Y74 HydrophobicContact CB-CD2 3.52Å; P36-Y74 HydrophobicContact CB-CE2 4.1Å; P36-Y74 HydrophobicContact CB-CG 3.68Å; P36-Y74 HydrophobicContact CG-CD2 3.59Å; P36-Y74 HydrophobicContact CG-CE2 3.61Å; P36-Y74 HydrophobicContact CG-CG 4.06Å; N42-Y74 PolarHBondContact N-O 3.35Å; N42-Y74 WeakPolarHBondContact OD1-CB 3.48Å; N42-Y74 WeakPolarHBondContact OD1-CD2 3.48Å; N42-Y74 PolarHBondContact OD1-N 3.33Å; Y74-L76 PolarHBondContact O-N 3.41Å; Y74-K78 CarbonylContact C-O 3.39Å; Y74-K78 WeakPolarHBondContact CA-O 3.48Å; Y74-P79 HydrophobicContact CD1-CB 4.38Å; Y74-P79 HydrophobicContact CE1-CB 4Å
75F85.6Confident94.1Very high55 Ų5527.9 Ų27.924%0.24115%0.153CC..EExtended strand (participates in β ladder)trans-79.3100.2167.9-165.6-83.7000107.9M43 F73 H77 K78M43-F75 HydrophobicContact CE-CD2 3.91Å; M43-F75 HydrophobicContact CE-CE2 3.57Å; M43-F75 HydrophobicContact CE-CZ 4.33Å; M43-F75 HydrophobicContact CG-CD2 4.25Å; M43-F75 HydrophobicContact CG-CG 4.49Å; M43-F75 HydrophobicContact SD-CD2 3.51Å; M43-F75 VanDerWaalsContact SD-CD2 3.51Å; M43-F75 HydrophobicContact SD-CE2 3.84Å; M43-F75 HydrophobicContact SD-CG 4.24Å; F73-F75 HydrophobicContact CE1-CB 4.33Å; F73-F75 HydrophobicContact CE1-CD2 4.43Å; F75-H77 PolarHBondContact O-N 3.28Å; F75-H77 VanDerWaalsContact O-N 3.15Å; F75-K78 PolarHBondContact N-O 3.41Å; F75-K78 PolarHBondContact O-N 3.48Å
76L84.4Confident94.2Very high13 Ų1322.2 Ų22.27%0.06813%0.131CC..THydrogen-bonded Turntrans56.2-116.2-167.8-55167.1000109.8Y40 G41 Y74 I225 S229Y40-L76 HydrophobicContact CD1-CD2 4.43Å; G41-L76 WeakPolarHBondContact CA-O 3.27Å; G41-L76 PolarHBondContact N-O 2.86Å; Y74-L76 PolarHBondContact O-N 3.41Å; L76-I225 HydrophobicContact CD1-CG2 3.73Å; L76-I225 HydrophobicContact CD2-CG2 4.17Å; L76-S229 WeakPolarHBondContact CD1-OG 3.47Å
77H82.9Confident94.3Very high40 Ų4023.7 Ų23.719%0.18513%0.133CC..THydrogen-bonded Turntrans-94.1-4.6179.471.8-75.8000113.6F23 F75 S229 F230F23-H77 HydrophobicContact CE2-CB 4.05Å; F23-H77 HydrophobicContact CZ-CB 4.42Å; F75-H77 PolarHBondContact O-N 3.28Å; F75-H77 VanDerWaalsContact O-N 3.15Å; H77-S229 WeakPolarHBondContact CE1-CB 3.12Å; H77-S229 PolarHBondContact CE1-O 2.76Å; H77-S229 VanDerWaalsContact CE1-O 3.32Å; H77-F230 AromaticContact CD2-CZ 3.99Å; H77-F230 AromaticContact CE1-CE1 3.67Å; H77-F230 AromaticContact CE1-CE2 3.81Å; H77-F230 AromaticContact CE1-CZ 3.42Å; H77-F230 VanDerWaalsContact CE1-CZ 3.42Å; H77-F230 WeakPolarHBondContact CE1-CZ 3.48Å; H77-F230 AromaticContact ND1-CZ 3.97Å; H77-F230 AromaticContact NE2-CE1 3.31Å; H77-F230 VanDerWaalsContact NE2-CE1 3.31Å; H77-F230 WeakPolarHBondContact NE2-CE1 3.39Å; H77-F230 AromaticContact NE2-CZ 3.42Å; H77-F230 WeakPolarHBondContact NE2-CZ 3.42Å
78K87.6Confident94.6Very high57 Ų5720.6 Ų20.625%0.24810%0.101CC..EExtended strand (participates in β ladder)trans-95.2129.6-174.8-72.1-178.8176.2155.90111.6Y74 F75 F228 S229 P231Y74-K78 CarbonylContact C-O 3.39Å; Y74-K78 WeakPolarHBondContact CA-O 3.48Å; F75-K78 PolarHBondContact N-O 3.41Å; F75-K78 PolarHBondContact O-N 3.48Å; K78-F228 PolarHBondContact NZ-O 3.19Å; K78-S229 WeakPolarHBondContact CE-O 3.39Å; K78-S229 PolarHBondContact NZ-O 3.32Å; K78-P231 VanDerWaalsContact NZ-CD 3.34Å
79P93.5Very high94.6Very high26 Ų2617.2 Ų17.217%0.1699%0.086CC..EExtended strand (participates in β ladder)trans-66.4139.3169.128.8-33000110.7Y25 W26 F73 Y74Y25-P79 HydrophobicContact CD1-CB 3.51Å; Y25-P79 HydrophobicContact CD1-CG 4Å; Y25-P79 HydrophobicContact CD2-CG 4.18Å; Y25-P79 HydrophobicContact CE1-CB 3.99Å; Y25-P79 HydrophobicContact CE1-CG 4.37Å; Y25-P79 HydrophobicContact CG-CB 3.88Å; Y25-P79 HydrophobicContact CG-CG 3.92Å; W26-P79 HydrophobicContact CZ2-CB 4.09Å; F73-P79 CarbonylContact O-C 3.58Å; F73-P79 WeakPolarHBondContact O-CA 3.28Å; Y74-P79 HydrophobicContact CD1-CB 4.38Å; Y74-P79 HydrophobicContact CE1-CB 4Å
80A95.9Very high94.7Very high1 Ų119.1 Ų19.11%0.0089%0.094CC..EExtended strand (participates in β ladder)trans-138.3141.6174.100000109.8W26 F73 Q402 I404W26-A80 WeakPolarHBondContact CZ2-O 3.38Å; F73-A80 WeakPolarHBondContact CA-O 3.28Å; F73-A80 WeakPolarHBondContact CB-O 3.4Å; F73-A80 HydrophobicContact CD1-CB 4.49Å; F73-A80 PolarHBondContact N-O 3.47Å; F73-A80 PolarHBondContact O-N 2.67Å; F73-A80 VanDerWaalsContact O-O 3.07Å; A80-Q402 CarbonylContact C-O 3.58Å; A80-Q402 WeakPolarHBondContact CA-O 3.42Å; A80-Q402 HydrophobicContact CB-CB 3.94Å; A80-Q402 WeakPolarHBondContact CB-O 3.38Å; A80-I404 HydrophobicContact CB-CD1 3.82Å; A80-I404 HydrophobicContact CB-CG1 4.19Å
81A98.1Very high94.7Very high0 Ų019.9 Ų19.90%010%0.098CC..EExtended strand (participates in β ladder)trans-81.1116.317200000108.3W26 F70 I83 I397 T401 Q402 V403 I404W26-A81 HydrophobicContact CH2-CB 4.07Å; F70-A81 HydrophobicContact CD2-CB 3.82Å; F70-A81 HydrophobicContact CE2-CB 4.24Å; F70-A81 HydrophobicContact CG-CB 4.31Å; A81-I83 HydrophobicContact CB-CD1 4.34Å; A81-I397 HydrophobicContact CB-CD1 4.25Å; A81-I397 HydrophobicContact CB-CG1 4.24Å; A81-I397 HydrophobicContact CB-CG2 4.35Å; A81-T401 HydrophobicContact CB-CG2 4.38Å; A81-Q402 PolarHBondContact N-O 2.91Å; A81-V403 HydrophobicContact CB-CG2 4.4Å; A81-V403 CarbonylContact O-C 3.52Å; A81-V403 WeakPolarHBondContact O-CA 3.23Å; A81-I404 PolarHBondContact O-N 2.65Å
82F98.2Very high94.7Very high0 Ų019.9 Ų19.90%010%0.098CC..EExtended strand (participates in β ladder)trans-95.5108.8176.7-172.7-84.5000108.8F56 Y59 Y60 F70 V71 F73 V84 I404 P406F56-F82 HydrophobicContact CB-CE2 4.41Å; F56-F82 HydrophobicContact CB-CZ 4.39Å; F56-F82 HydrophobicContact CD1-CD2 4.42Å; F56-F82 AromaticContact CD1-CE2 3.5Å; F56-F82 HydrophobicContact CD1-CE2 3.5Å; F56-F82 VanDerWaalsContact CD1-CE2 3.5Å; F56-F82 HydrophobicContact CD1-CZ 4.25Å; F56-F82 AromaticContact CE1-CE2 3.97Å; F56-F82 HydrophobicContact CE1-CE2 3.97Å; F56-F82 HydrophobicContact CG-CE2 4.15Å; Y59-F82 AromaticContact CD1-CD1 3.81Å; Y59-F82 HydrophobicContact CD1-CD1 3.81Å; Y59-F82 HydrophobicContact CD1-CD2 4.28Å; Y59-F82 AromaticContact CD1-CE1 3.93Å; Y59-F82 HydrophobicContact CD1-CE1 3.93Å; Y59-F82 HydrophobicContact CD1-CE2 4.4Å; Y59-F82 AromaticContact CD1-CG 3.98Å; Y59-F82 HydrophobicContact CD1-CG 3.98Å; Y59-F82 HydrophobicContact CD1-CZ 4.21Å; Y59-F82 HydrophobicContact CE1-CB 4.36Å; Y59-F82 HydrophobicContact CE1-CD1 4.28Å; Y59-F82 HydrophobicContact CE1-CG 4.23Å; Y60-F82 HydrophobicContact CD2-CE1 4.36Å; F70-F82 CarbonylContact C-O 3.04Å; F70-F82 VanDerWaalsContact CA-O 3.28Å; F70-F82 WeakPolarHBondContact CA-O 3.44Å; F70-F82 WeakPolarHBondContact CB-O 3.29Å; V71-F82 HydrophobicContact CG2-CB 4.15Å; V71-F82 HydrophobicContact CG2-CD1 4.07Å; V71-F82 PolarHBondContact N-O 3.46Å; V71-F82 PolarHBondContact O-N 3.44Å; F73-F82 HydrophobicContact CB-CB 3.76Å; F73-F82 HydrophobicContact CD2-CD2 4.24Å; F73-F82 HydrophobicContact CG-CB 4.43Å; F73-F82 HydrophobicContact CG-CD2 4.39Å; F82-V84 HydrophobicContact CD1-CG1 3.99Å; F82-V84 HydrophobicContact CE1-CG1 4.27Å; F82-I404 HydrophobicContact CD2-CB 4.01Å; F82-I404 HydrophobicContact CD2-CG2 3.67Å; F82-I404 HydrophobicContact CE2-CG2 3.85Å; F82-P406 HydrophobicContact CD1-CG 4.49Å; F82-P406 HydrophobicContact CE1-CB 4.12Å; F82-P406 HydrophobicContact CE1-CG 3.66Å; F82-P406 HydrophobicContact CE2-CB 3.89Å; F82-P406 HydrophobicContact CE2-CG 4.21Å; F82-P406 HydrophobicContact CZ-CB 3.42Å; F82-P406 VanDerWaalsContact CZ-CB 3.42Å; F82-P406 HydrophobicContact CZ-CG 3.5Å
83I98.5Very high94.8Very high0 Ų019.9 Ų19.90%010%0.098CC..EExtended strand (participates in β ladder)trans-76.5127.5-172.9-49.9-51.9000108.7F70 A81 D85 L88 A89 I92 I397 V403 I404 I405 P406 Y410F70-I83 HydrophobicContact CB-CD1 3.69Å; F70-I83 HydrophobicContact CG-CD1 4.49Å; A81-I83 HydrophobicContact CB-CD1 4.34Å; I83-D85 VanDerWaalsContact CG2-O 3.28Å; I83-D85 WeakPolarHBondContact CG2-O 3.39Å; I83-L88 HydrophobicContact CD1-CD2 3.88Å; I83-L88 HydrophobicContact CD1-CG 4.33Å; I83-L88 HydrophobicContact CG2-CB 4.11Å; I83-L88 HydrophobicContact CG2-CD2 4.21Å; I83-L88 HydrophobicContact CG2-CG 4.06Å; I83-A89 HydrophobicContact CG2-CB 4.16Å; I83-I92 HydrophobicContact CD1-CD1 3.7Å; I83-I92 HydrophobicContact CG1-CD1 3.97Å; I83-I397 HydrophobicContact CD1-CD1 4.31Å; I83-V403 HydrophobicContact CD1-CG1 3.8Å; I83-V403 HydrophobicContact CG1-CG1 3.56Å; I83-I404 PolarHBondContact N-O 3.21Å; I83-I405 HydrophobicContact CB-CG1 4.26Å; I83-I405 HydrophobicContact CG1-CG1 3.95Å; I83-P406 WeakPolarHBondContact O-CD 3.12Å; I83-P406 WeakPolarHBondContact O-CG 3.26Å; I83-Y410 WeakPolarHBondContact CG2-OH 3.35Å; I83-Y410 PolarHBondContact O-OH 3.41Å
84V97.3Very high94.9Very high7 Ų722.8 Ų22.84%0.04211%0.113CC..  trans-112.2-22.4177.5-61.90000112.1Y60 F68 P69 V71 F82Y60-V84 HydrophobicContact CD2-CB 4.27Å; Y60-V84 HydrophobicContact CD2-CG1 4.14Å; Y60-V84 HydrophobicContact CE2-CB 4.11Å; Y60-V84 HydrophobicContact CE2-CG1 4.48Å; Y60-V84 WeakPolarHBondContact CE2-O 3.37Å; F68-V84 WeakPolarHBondContact O-CG2 3.49Å; P69-V84 WeakPolarHBondContact O-CG2 3.4Å; P69-V84 PolarHBondContact O-N 2.94Å; V71-V84 HydrophobicContact CG2-CG1 3.98Å; F82-V84 HydrophobicContact CD1-CG1 3.99Å; F82-V84 HydrophobicContact CE1-CG1 4.27Å
85D96.8Very high95.2Very high55 Ų5528.8 Ų28.829%0.29414%0.139SC..  trans-93.1127.8176.3169.736000111.6P69 I83 Q87 L88 A89 Y410P69-D85 HydrophobicContact CB-CB 3.98Å; P69-D85 PolarHBondContact O-N 3.36Å; I83-D85 VanDerWaalsContact CG2-O 3.28Å; I83-D85 WeakPolarHBondContact CG2-O 3.39Å; D85-Q87 VanDerWaalsContact C-N 3.29Å; D85-Q87 PolarHBondContact O-N 2.89Å; D85-Q87 PolarHBondContact OD1-N 3.47Å; D85-Q87 WeakPolarHBondContact OD2-CB 3.21Å; D85-L88 HydrophobicContact CB-CB 4.26Å; D85-L88 PolarHBondContact O-N 3.22Å; D85-L88 PolarHBondContact OD2-N 3.49Å; D85-A89 PolarHBondContact O-N 3.19Å; D85-Y410 PolarHBondContact O-OH 3.43Å
86T96.9Very high95.8Very high28 Ų2828.7 Ų28.717%0.17214%0.141CC..Hα-helixtrans-67.2-30.5177.656.20000111.5A89 K90 Y410 L416 E440T86-A89 WeakPolarHBondContact O-CB 3.3Å; T86-A89 PolarHBondContact O-N 3.37Å; T86-K90 PolarHBondContact O-N 3.43Å; T86-Y410 HydrophobicContact CG2-CD2 4.04Å; T86-Y410 HydrophobicContact CG2-CE2 3.96Å; T86-Y410 HydrophobicContact CG2-CG 4.37Å; T86-L416 HydrophobicContact CG2-CD1 4.08Å; T86-E440 HydrophobicContact CG2-CG 4.35Å
87Q96.9Very high96.4Very high75 Ų7529.2 Ų29.235%0.3514%0.143SC..Hα-helixtrans-68.9-40.3177.7-175.75469.500111.7D85 A89 K90 N91D85-Q87 VanDerWaalsContact C-N 3.29Å; D85-Q87 PolarHBondContact O-N 2.89Å; D85-Q87 PolarHBondContact OD1-N 3.47Å; D85-Q87 WeakPolarHBondContact OD2-CB 3.21Å; Q87-A89 VanDerWaalsContact C-N 3.35Å; Q87-K90 WeakPolarHBondContact O-CB 3.32Å; Q87-K90 PolarHBondContact O-N 3.21Å; Q87-N91 PolarHBondContact NE2-OD1 2.95Å; Q87-N91 VanDerWaalsContact NE2-OD1 3.11Å; Q87-N91 VanDerWaalsContact O-CG 3.3Å; Q87-N91 PolarHBondContact O-N 2.62Å; Q87-N91 PolarHBondContact O-OD1 3.12Å
88L98.4Very high97.1Very high2 Ų232.1 Ų32.11%0.0117%0.168CC..Hα-helixtrans-63.1-40.2169.2179.855.6000111.6P69 F70 I83 D85 K90 N91 I92 Y387 V389P69-L88 HydrophobicContact CB-CB 4.31Å; P69-L88 HydrophobicContact CB-CD2 3.82Å; P69-L88 HydrophobicContact CG-CD2 4.35Å; F70-L88 HydrophobicContact CB-CD2 4.13Å; F70-L88 HydrophobicContact CD1-CD2 3.95Å; I83-L88 HydrophobicContact CD1-CD2 3.88Å; I83-L88 HydrophobicContact CD1-CG 4.33Å; I83-L88 HydrophobicContact CG2-CB 4.11Å; I83-L88 HydrophobicContact CG2-CD2 4.21Å; I83-L88 HydrophobicContact CG2-CG 4.06Å; D85-L88 HydrophobicContact CB-CB 4.26Å; D85-L88 PolarHBondContact O-N 3.22Å; D85-L88 PolarHBondContact OD2-N 3.49Å; L88-K90 VanDerWaalsContact C-N 3.32Å; L88-K90 PolarHBondContact O-N 2.88Å; L88-N91 PolarHBondContact O-N 3.22Å; L88-I92 HydrophobicContact CD1-CD1 3.83Å; L88-I92 HydrophobicContact CD1-CG1 4.05Å; L88-I92 HydrophobicContact CD2-CD1 4.45Å; L88-I92 HydrophobicContact CG-CD1 3.79Å; L88-I92 HydrophobicContact CG-CG1 4.44Å; L88-I92 WeakPolarHBondContact O-CG1 3.38Å; L88-I92 PolarHBondContact O-N 3.45Å; L88-Y387 HydrophobicContact CD1-CE1 3.84Å; L88-V389 HydrophobicContact CD1-CG1 4.08Å; L88-V389 HydrophobicContact CD1-CG2 4.36Å; L88-V389 HydrophobicContact CD2-CG1 4.2Å; L88-V389 HydrophobicContact CD2-CG2 4.22Å
89A98.5Very high97.6Very high0 Ų030.2 Ų30.20%016%0.16CC..Hα-helixtrans-59.5-41.517400000112.1I83 D85 T86 Q87 N91 I92 L93 I405 Y410I83-A89 HydrophobicContact CG2-CB 4.16Å; D85-A89 PolarHBondContact O-N 3.19Å; T86-A89 WeakPolarHBondContact O-CB 3.3Å; T86-A89 PolarHBondContact O-N 3.37Å; Q87-A89 VanDerWaalsContact C-N 3.35Å; A89-N91 PolarHBondContact O-N 3.46Å; A89-I92 PolarHBondContact O-N 3.43Å; A89-L93 VanDerWaalsContact O-CB 3.29Å; A89-L93 WeakPolarHBondContact O-CB 3.35Å; A89-L93 VanDerWaalsContact O-CG 3.26Å; A89-L93 WeakPolarHBondContact O-CG 3.39Å; A89-L93 PolarHBondContact O-N 2.85Å; A89-I405 HydrophobicContact CB-CD1 4.37Å; A89-I405 HydrophobicContact CB-CG2 3.94Å; A89-Y410 HydrophobicContact CB-CE2 3.97Å
90K98.3Very high97.9Very high43 Ų4329 Ų2919%0.18715%0.152CC..Hα-helixtrans-60.2-41.9173.3-172.3171.6179.2175.60112.5T86 Q87 L88 I94 K95 E437 V439T86-K90 PolarHBondContact O-N 3.43Å; Q87-K90 WeakPolarHBondContact O-CB 3.32Å; Q87-K90 PolarHBondContact O-N 3.21Å; L88-K90 VanDerWaalsContact C-N 3.32Å; L88-K90 PolarHBondContact O-N 2.88Å; K90-I94 HydrophobicContact CG-CD1 4.13Å; K90-I94 WeakPolarHBondContact O-CB 3.46Å; K90-I94 PolarHBondContact O-N 3.43Å; K90-K95 PolarHBondContact O-N 3.28Å; K90-E437 IonicContact NZ-OE1 2.88Å; K90-E437 PolarHBondContact NZ-OE1 3.39Å; K90-E437 VanDerWaalsContact NZ-OE1 3.12Å; K90-E437 IonicContact NZ-OE2 3.29Å; K90-E437 PolarHBondContact NZ-OE2 3.24Å; K90-V439 HydrophobicContact CB-CG1 3.95Å; K90-V439 HydrophobicContact CB-CG2 3.91Å; K90-V439 HydrophobicContact CG-CG1 4.33Å
91N98.4Very high97.9Very high15 Ų1529.7 Ų29.78%0.0816%0.158CC..Iπ-helixtrans-63.2-49.4176.5-64.2-9.9000110.5Q87 L88 A89 L93 K95 D96 Y387Q87-N91 PolarHBondContact NE2-OD1 2.95Å; Q87-N91 VanDerWaalsContact NE2-OD1 3.11Å; Q87-N91 VanDerWaalsContact O-CG 3.3Å; Q87-N91 PolarHBondContact O-N 2.62Å; Q87-N91 PolarHBondContact O-OD1 3.12Å; L88-N91 PolarHBondContact O-N 3.22Å; A89-N91 PolarHBondContact O-N 3.46Å; N91-L93 PolarHBondContact O-N 3.46Å; N91-K95 PolarHBondContact O-N 2.94Å; N91-K95 VanDerWaalsContact O-N 3.16Å; N91-K95 WeakPolarHBondContact OD1-CD 3.44Å; N91-D96 WeakPolarHBondContact O-CA 3.47Å; N91-D96 PolarHBondContact O-N 3.13Å; N91-Y387 WeakPolarHBondContact CB-OH 3.37Å
92I98.6Very high97.9Very high0 Ų030.7 Ų30.70%016%0.163CC..Iπ-helixtrans-64.4-43.1-178.1-70170.9000112.6I83 L88 A89 F100 R381 I397 V403 I405I83-I92 HydrophobicContact CD1-CD1 3.7Å; I83-I92 HydrophobicContact CG1-CD1 3.97Å; L88-I92 HydrophobicContact CD1-CD1 3.83Å; L88-I92 HydrophobicContact CD1-CG1 4.05Å; L88-I92 HydrophobicContact CD2-CD1 4.45Å; L88-I92 HydrophobicContact CG-CD1 3.79Å; L88-I92 HydrophobicContact CG-CG1 4.44Å; L88-I92 WeakPolarHBondContact O-CG1 3.38Å; L88-I92 PolarHBondContact O-N 3.45Å; A89-I92 PolarHBondContact O-N 3.43Å; I92-F100 HydrophobicContact CB-CD2 4.19Å; I92-F100 HydrophobicContact CB-CE2 4.42Å; I92-F100 HydrophobicContact CB-CG 4.41Å; I92-F100 HydrophobicContact CD1-CZ 4.49Å; I92-F100 HydrophobicContact CG1-CD2 4.07Å; I92-F100 HydrophobicContact CG1-CE1 4.35Å; I92-F100 HydrophobicContact CG1-CE2 3.8Å; I92-F100 HydrophobicContact CG1-CG 4.47Å; I92-F100 HydrophobicContact CG1-CZ 3.95Å; I92-F100 HydrophobicContact CG2-CB 4Å; I92-F100 HydrophobicContact CG2-CD1 4.06Å; I92-F100 HydrophobicContact CG2-CD2 4.05Å; I92-F100 HydrophobicContact CG2-CG 3.77Å; I92-R381 HydrophobicContact CG2-CB 4.16Å; I92-R381 HydrophobicContact CG2-CG 3.94Å; I92-I397 HydrophobicContact CD1-CD1 4.19Å; I92-V403 HydrophobicContact CD1-CG1 3.95Å; I92-V403 HydrophobicContact CG2-CG1 4.29Å; I92-I405 HydrophobicContact CG2-CD1 4.13Å
93L98.6Very high97.7Very high0 Ų032.2 Ų32.20%017%0.169CC..Iπ-helixtrans-78.6-34-175.3-68.6175.6000112.9A89 N91 L379 R381 I405 V439 L442 D446 G447A89-L93 VanDerWaalsContact O-CB 3.29Å; A89-L93 WeakPolarHBondContact O-CB 3.35Å; A89-L93 VanDerWaalsContact O-CG 3.26Å; A89-L93 WeakPolarHBondContact O-CG 3.39Å; A89-L93 PolarHBondContact O-N 2.85Å; N91-L93 PolarHBondContact O-N 3.46Å; L93-L379 HydrophobicContact CD1-CD1 3.98Å; L93-L379 HydrophobicContact CD2-CD1 4.11Å; L93-R381 HydrophobicContact CD2-CG 4.37Å; L93-R381 VanDerWaalsContact CD2-NH2 3.29Å; L93-I405 HydrophobicContact CD1-CD1 3.88Å; L93-I405 HydrophobicContact CD2-CD1 3.6Å; L93-I405 HydrophobicContact CG-CD1 3.57Å; L93-V439 HydrophobicContact CD1-CG1 4.24Å; L93-L442 HydrophobicContact CD1-CD1 4.26Å; L93-L442 HydrophobicContact CD1-CD2 3.91Å; L93-D446 HydrophobicContact CD1-CB 4.24Å; L93-G447 WeakPolarHBondContact O-CA 3.09Å
94I98.2Very high97.3Very high62 Ų6233 Ų3332%0.31818%0.178SC..Iπ-helixtrans-121.7-66.3-168.2-58.5160.1000111.7K90 F97 V439 D446K90-I94 HydrophobicContact CG-CD1 4.13Å; K90-I94 WeakPolarHBondContact O-CB 3.46Å; K90-I94 PolarHBondContact O-N 3.43Å; I94-F97 WeakPolarHBondContact O-CB 3.39Å; I94-V439 HydrophobicContact CD1-CG1 4.16Å; I94-D446 WeakPolarHBondContact CD1-OD2 3.2Å
95K97.9Very high96.9Very high126 Ų12634.5 Ų34.555%0.54818%0.184SC..Iπ-helixtrans-67.8-48.2-166.5-58.6-172.5-173.8164.70112.6K90 N91K90-K95 PolarHBondContact O-N 3.28Å; N91-K95 PolarHBondContact O-N 2.94Å; N91-K95 VanDerWaalsContact O-N 3.16Å; N91-K95 WeakPolarHBondContact OD1-CD 3.44Å
96D97.9Very high96.5Very high52 Ų5232.1 Ų32.128%0.27817%0.171SC..THydrogen-bonded Turntrans-105.224.2-176-56.5-43.2000111.4N91 S98 N99 F100 Y387N91-D96 WeakPolarHBondContact O-CA 3.47Å; N91-D96 PolarHBondContact O-N 3.13Å; D96-S98 PolarHBondContact O-N 2.68Å; D96-N99 PolarHBondContact O-N 2.89Å; D96-F100 HydrophobicContact CB-CD2 4.44Å; D96-F100 HydrophobicContact CB-CE2 4.41Å; D96-F100 WeakPolarHBondContact O-CD2 3.41Å; D96-Y387 HydrophobicContact CB-CE2 3.86Å; D96-Y387 VanDerWaalsContact OD2-CE2 3.31Å; D96-Y387 WeakPolarHBondContact OD2-CE2 3.39Å; D96-Y387 PolarHBondContact OD2-OH 2.94Å
97F97.8Very high96.1Very high25 Ų2533.6 Ų33.611%0.1118%0.176CC..G310 helixtrans-52-32.9-176.2173.7-98.7000113I94 N99 F100 A101 W126 P448 R449I94-F97 WeakPolarHBondContact O-CB 3.39Å; F97-N99 PolarHBondContact O-N 3Å; F97-F100 CarbonylContact O-C 3.52Å; F97-F100 VanDerWaalsContact O-C 3.28Å; F97-F100 PolarHBondContact O-N 3.48Å; F97-A101 HydrophobicContact CE1-CB 3.93Å; F97-A101 HydrophobicContact CZ-CB 3.88Å; F97-A101 WeakPolarHBondContact O-CA 3.31Å; F97-A101 PolarHBondContact O-N 3.1Å; F97-W126 AromaticContact CE1-CH2 3.91Å; F97-W126 HydrophobicContact CE1-CH2 3.91Å; F97-W126 AromaticContact CE1-CZ3 3.96Å; F97-W126 HydrophobicContact CE1-CZ3 3.96Å; F97-W126 AromaticContact CZ-CH2 3.47Å; F97-W126 HydrophobicContact CZ-CH2 3.47Å; F97-W126 VanDerWaalsContact CZ-CH2 3.47Å; F97-W126 HydrophobicContact CZ-CZ2 4.33Å; F97-W126 AromaticContact CZ-CZ3 3.73Å; F97-W126 HydrophobicContact CZ-CZ3 3.73Å; F97-P448 HydrophobicContact CB-CG 4.42Å; F97-P448 HydrophobicContact CD1-CB 3.91Å; F97-P448 HydrophobicContact CD1-CG 3.63Å; F97-P448 HydrophobicContact CD2-CG 4.3Å; F97-P448 HydrophobicContact CE1-CB 3.69Å; F97-P448 HydrophobicContact CE1-CG 3.97Å; F97-P448 HydrophobicContact CE2-CB 4.32Å; F97-P448 HydrophobicContact CG-CB 4.33Å; F97-P448 HydrophobicContact CG-CG 3.83Å; F97-P448 HydrophobicContact CZ-CB 3.91Å; F97-P448 HydrophobicContact CZ-CG 4.45Å; F97-R449 HydrophobicContact CE2-CB 3.64Å; F97-R449 HydrophobicContact CZ-CB 3.9Å
98S97.3Very high95.8Very high101 Ų10130.4 Ų30.471%0.70616%0.161SC*.G310 helixtrans-57.1-31177.759.20000113D96D96-S98 PolarHBondContact O-N 2.68Å
99N98.3Very high95.3Very high17 Ų1731.1 Ų31.19%0.09117%0.169CC..G310 helixtrans-86-11.8175.9-164.546.7000113.5D96 F97 A383 L384 N385D96-N99 PolarHBondContact O-N 2.89Å; F97-N99 PolarHBondContact O-N 3Å; N99-A383 CarbonylContact O-C 3.28Å; N99-L384 WeakPolarHBondContact O-CB 3.19Å; N99-L384 WeakPolarHBondContact O-CG 3.49Å; N99-L384 PolarHBondContact O-N 2.96Å; N99-N385 PolarHBondContact ND2-O 3.26Å; N99-N385 WeakPolarHBondContact OD1-CA 3.33Å; N99-N385 VanDerWaalsContact OD1-CB 3.24Å; N99-N385 WeakPolarHBondContact OD1-CB 3.45Å; N99-N385 PolarHBondContact OD1-N 3.07Å; N99-N385 PolarHBondContact OD1-ND2 2.91Å; N99-N385 PolarHBondContact OD1-O 2.99Å
100F98.3Very high94.8Very high0 Ų039.6 Ų39.60%020%0.201CC..SBendtrans-124.421-175.3-64.2-75.5000111.9I92 D96 F97 D102 R381 A383 Y387 I397 V403I92-F100 HydrophobicContact CB-CD2 4.19Å; I92-F100 HydrophobicContact CB-CE2 4.42Å; I92-F100 HydrophobicContact CB-CG 4.41Å; I92-F100 HydrophobicContact CD1-CZ 4.49Å; I92-F100 HydrophobicContact CG1-CD2 4.07Å; I92-F100 HydrophobicContact CG1-CE1 4.35Å; I92-F100 HydrophobicContact CG1-CE2 3.8Å; I92-F100 HydrophobicContact CG1-CG 4.47Å; I92-F100 HydrophobicContact CG1-CZ 3.95Å; I92-F100 HydrophobicContact CG2-CB 4Å; I92-F100 HydrophobicContact CG2-CD1 4.06Å; I92-F100 HydrophobicContact CG2-CD2 4.05Å; I92-F100 HydrophobicContact CG2-CG 3.77Å; D96-F100 HydrophobicContact CB-CD2 4.44Å; D96-F100 HydrophobicContact CB-CE2 4.41Å; D96-F100 WeakPolarHBondContact O-CD2 3.41Å; F97-F100 CarbonylContact O-C 3.52Å; F97-F100 VanDerWaalsContact O-C 3.28Å; F97-F100 PolarHBondContact O-N 3.48Å; F100-D102 PolarHBondContact O-N 3.43Å; F100-D102 VanDerWaalsContact O-N 3.08Å; F100-R381 HydrophobicContact CB-CB 4.15Å; F100-R381 HydrophobicContact CB-CG 4.46Å; F100-R381 HydrophobicContact CD1-CB 4.45Å; F100-R381 WeakPolarHBondContact O-CD 3.21Å; F100-A383 HydrophobicContact CD1-CB 4.33Å; F100-A383 HydrophobicContact CE1-CB 3.82Å; F100-Y387 HydrophobicContact CE2-CD1 4.15Å; F100-Y387 AromaticContact CE2-CD2 3.74Å; F100-Y387 HydrophobicContact CE2-CD2 3.74Å; F100-Y387 HydrophobicContact CE2-CE1 4.33Å; F100-Y387 AromaticContact CE2-CE2 3.93Å; F100-Y387 HydrophobicContact CE2-CE2 3.93Å; F100-Y387 AromaticContact CE2-CG 3.84Å; F100-Y387 HydrophobicContact CE2-CG 3.84Å; F100-Y387 AromaticContact CZ-CD1 3.76Å; F100-Y387 HydrophobicContact CZ-CD1 3.76Å; F100-Y387 AromaticContact CZ-CD2 3.95Å; F100-Y387 HydrophobicContact CZ-CD2 3.95Å; F100-Y387 HydrophobicContact CZ-CE1 4.29Å; F100-Y387 HydrophobicContact CZ-CE2 4.46Å; F100-Y387 AromaticContact CZ-CG 3.55Å; F100-Y387 HydrophobicContact CZ-CG 3.55Å; F100-I397 HydrophobicContact CE1-CG2 4.5Å; F100-V403 HydrophobicContact CD1-CG2 4.25Å; F100-V403 HydrophobicContact CE1-CG2 4Å
101A97.1Very high94.4Very high16 Ų1639.4 Ų39.413%0.13220%0.202CC..  trans-62-27-170.100000113.2F97 L384 R449F97-A101 HydrophobicContact CE1-CB 3.93Å; F97-A101 HydrophobicContact CZ-CB 3.88Å; F97-A101 WeakPolarHBondContact O-CA 3.31Å; F97-A101 PolarHBondContact O-N 3.1Å; A101-L384 HydrophobicContact CB-CD1 4.28Å; A101-R449 WeakPolarHBondContact O-CD 3.45Å; A101-R449 PolarHBondContact O-NH1 3.48Å
102D97.1Very high94.1Very high21 Ų2138.7 Ų38.711%0.11220%0.198CC..BIsolated β-bridgetrans-91152.7-173.7-73.6-2.2000113.7F100 D122 G123 R381 K382 L384 R449F100-D102 PolarHBondContact O-N 3.43Å; F100-D102 VanDerWaalsContact O-N 3.08Å; D102-D122 VanDerWaalsContact CA-OD1 3.29Å; D102-D122 WeakPolarHBondContact CA-OD1 3.5Å; D102-D122 HydrophobicContact CB-CB 4.18Å; D102-D122 WeakPolarHBondContact CB-OD1 3.41Å; D102-D122 WeakPolarHBondContact OD1-CB 3.47Å; D102-G123 PolarHBondContact OD1-N 2.9Å; D102-R381 CarbonylContact O-C 3.57Å; D102-R381 VanDerWaalsContact O-CA 3.29Å; D102-R381 WeakPolarHBondContact O-CA 3.04Å; D102-K382 HydrophobicContact CB-CB 4.27Å; D102-K382 PolarHBondContact O-N 2.86Å; D102-L384 HydrophobicContact CB-CD2 4.01Å; D102-L384 WeakPolarHBondContact OD2-CD2 3.13Å; D102-R449 IonicContact OD1-NH1 3.76Å
103R94.4Very high93.8Very high32 Ų3239.8 Ų39.812%0.12121%0.206CC..  trans-98.1-26.1167.1-65.6-177.9-178.7159.3-8.9112.1Q105 F119 D122 Q402 R449R103-Q105 VanDerWaalsContact C-N 3.34Å; R103-Q105 HydrophobicContact CB-CG 4.04Å; R103-F119 PolarHBondContact NH1-O 3Å; R103-D122 PolarHBondContact N-OD1 2.71Å; R103-Q402 PolarHBondContact O-NE2 3.42Å; R103-Q402 PolarHBondContact O-OE1 2.76Å; R103-R449 PolarHBondContact NH2-O 3.43Å
104G90.1Very high93.6Very high17 Ų1739.8 Ų39.818%0.17521%0.206CC..  trans70.329.4-178.200000113.9D122G104-D122 WeakPolarHBondContact CA-OD2 3.37Å; G104-D122 PolarHBondContact N-OD2 2.89Å
105Q88.1Confident93.4Very high37 Ų3736.9 Ų36.917%0.17319%0.19CC..  trans-77.3161.5179.6-77.2-62.2-35.200112.4R103 N120 E380R103-Q105 VanDerWaalsContact C-N 3.34Å; R103-Q105 HydrophobicContact CB-CG 4.04Å; Q105-N120 HydrophobicContact CB-CB 4.42Å; Q105-E380 PolarHBondContact NE2-OE2 2.75Å
106F89.3Confident93.2Very high5 Ų532.1 Ų32.12%0.02217%0.17CC..  trans-72.3132.4175.8175.1-98.8000110.9N108 T115 N120 V227 P231 A234 M241F106-N108 HydrophobicContact CE1-CB 4.21Å; F106-N108 HydrophobicContact CE2-CB 4.35Å; F106-N108 HydrophobicContact CZ-CB 3.69Å; F106-T115 HydrophobicContact CE1-CG2 4.48Å; F106-N120 PolarHBondContact O-ND2 2.87Å; F106-V227 HydrophobicContact CB-CG1 4.12Å; F106-V227 HydrophobicContact CD1-CG1 3.72Å; F106-V227 HydrophobicContact CD2-CG1 3.67Å; F106-V227 HydrophobicContact CE1-CG1 4Å; F106-V227 HydrophobicContact CE2-CG1 3.94Å; F106-V227 HydrophobicContact CG-CG1 3.54Å; F106-V227 HydrophobicContact CZ-CG1 4.09Å; F106-P231 HydrophobicContact CB-CB 4.02Å; F106-P231 HydrophobicContact CD2-CB 3.86Å; F106-P231 HydrophobicContact CG-CB 4.44Å; F106-A234 HydrophobicContact CD2-CB 4.43Å; F106-A234 HydrophobicContact CE2-CB 3.92Å; F106-M241 HydrophobicContact CD1-CB 4.11Å; F106-M241 HydrophobicContact CD1-CE 4.31Å; F106-M241 HydrophobicContact CD1-SD 4.08Å; F106-M241 HydrophobicContact CE1-CB 3.94Å
107H89.4Confident93Very high59 Ų5930.4 Ų30.427%0.27316%0.16SC..  trans-148.1142.516364.979.2000110.2T115 N120H107-T115 WeakPolarHBondContact CA-OG1 3.46Å; H107-T115 WeakPolarHBondContact CB-O 3.5Å; H107-N120 HydrophobicContact CB-CB 4.25Å
108N90.3Very high92.9Very high8 Ų829.8 Ų29.84%0.04316%0.158CC..BIsolated β-bridgetrans-135.784.2176.4-1788.1000109.9F106 R110 D111 D112 T115 M239F106-N108 HydrophobicContact CE1-CB 4.21Å; F106-N108 HydrophobicContact CE2-CB 4.35Å; F106-N108 HydrophobicContact CZ-CB 3.69Å; N108-R110 PolarHBondContact O-N 2.94Å; N108-R110 PolarHBondContact OD1-N 3.48Å; N108-D111 WeakPolarHBondContact ND2-CB 3.16Å; N108-D111 PolarHBondContact ND2-OD2 3.28Å; N108-D111 PolarHBondContact OD1-N 3.38Å; N108-D111 PolarHBondContact OD1-OD2 2.86Å; N108-D112 HydrophobicContact CB-CB 4.33Å; N108-D112 CarbonylContact O-C 3.31Å; N108-D112 WeakPolarHBondContact O-CA 3.34Å; N108-D112 WeakPolarHBondContact O-CB 3.3Å; N108-D112 PolarHBondContact O-N 3.43Å; N108-T115 PolarHBondContact N-OG1 2.99Å; N108-M239 PolarHBondContact ND2-O 2.88Å; N108-M239 VanDerWaalsContact ND2-O 3.12Å
109G87.4Confident92.7Very high18 Ų1829.4 Ų29.419%0.18614%0.144CC..THydrogen-bonded Turntrans-67.3-21-176.400000115.6Q116G109-Q116 VanDerWaalsContact CA-CG 3.47Å; G109-Q116 VanDerWaalsContact CA-NE2 3.32Å
110R87.3Confident92.5Very high178 Ų17829 Ų2967%0.67214%0.142SC*.THydrogen-bonded Turntrans-70.8-51.4-179.5-179.4-169.2172.3169.34.6111N108N108-R110 PolarHBondContact O-N 2.94Å; N108-R110 PolarHBondContact OD1-N 3.48Å
111D90.3Very high92.4Very high38 Ų3829.1 Ų29.120%0.20314%0.142CC..THydrogen-bonded Turntrans-107-16.6-173.7-43.6-76.8000112.5N108 R238 R240N108-D111 WeakPolarHBondContact ND2-CB 3.16Å; N108-D111 PolarHBondContact ND2-OD2 3.28Å; N108-D111 PolarHBondContact OD1-N 3.38Å; N108-D111 PolarHBondContact OD1-OD2 2.86Å; D111-R238 HydrophobicContact CB-CB 4.44Å; D111-R238 WeakPolarHBondContact OD2-CA 3.14Å; D111-R238 WeakPolarHBondContact OD2-CB 3.37Å; D111-R238 WeakPolarHBondContact OD2-CG 3.49Å; D111-R240 HydrophobicContact CB-CG 4.39Å; D111-R240 VanDerWaalsContact O-CD 3.22Å; D111-R240 WeakPolarHBondContact O-CD 3.28Å; D111-R240 WeakPolarHBondContact O-CG 3.45Å; D111-R240 PolarHBondContact O-NE 3.46Å
112D91.8Very high92.3Very high0 Ų029.8 Ų29.80%014%0.144CC..BIsolated β-bridgetrans-136.367.4177-1617.4000112.8N108 L114 T115 R240 M241 M242N108-D112 HydrophobicContact CB-CB 4.33Å; N108-D112 CarbonylContact O-C 3.31Å; N108-D112 WeakPolarHBondContact O-CA 3.34Å; N108-D112 WeakPolarHBondContact O-CB 3.3Å; N108-D112 PolarHBondContact O-N 3.43Å; D112-L114 PolarHBondContact O-N 3.4Å; D112-L114 VanDerWaalsContact O-N 3.07Å; D112-T115 HydrophobicContact CB-CG2 4.09Å; D112-T115 WeakPolarHBondContact O-CB 3.3Å; D112-T115 PolarHBondContact O-N 3.49Å; D112-T115 PolarHBondContact O-OG1 3.46Å; D112-T115 WeakPolarHBondContact OD2-CG2 3.33Å; D112-R240 HydrophobicContact CB-CB 4.07Å; D112-R240 HydrophobicContact CB-CG 4.09Å; D112-M241 PolarHBondContact OD2-N 3.47Å; D112-M242 PolarHBondContact OD2-N 3.05Å
113P93.3Very high92.1Very high24 Ų2430.4 Ų30.416%0.15616%0.155CC..G310 helixtrans-48-40-172.8-30.233000115.3T115 Q116 A302P113-T115 PolarHBondContact O-N 3.11Å; P113-Q116 WeakPolarHBondContact O-CB 3.47Å; P113-Q116 PolarHBondContact O-N 2.94Å; P113-A302 WeakPolarHBondContact O-CB 3.26Å
114L94.4Very high92Very high0 Ų035.1 Ų35.10%018%0.177CC..G310 helixtrans-60.3-21-177.5-63.6-170.9000113.4D112 Q116 H117 M242 H247 F250 M251 A301 F305D112-L114 PolarHBondContact O-N 3.4Å; D112-L114 VanDerWaalsContact O-N 3.07Å; L114-Q116 VanDerWaalsContact C-N 3.27Å; L114-Q116 PolarHBondContact O-N 3.16Å; L114-H117 PolarHBondContact O-CD2 2.88Å; L114-M242 HydrophobicContact CB-CG 4.07Å; L114-H247 HydrophobicContact CD1-CB 4.33Å; L114-F250 HydrophobicContact CD1-CB 3.99Å; L114-F250 HydrophobicContact CD1-CD2 4.46Å; L114-F250 HydrophobicContact CD2-CB 4.18Å; L114-M251 HydrophobicContact CD2-SD 4.18Å; L114-A301 HydrophobicContact CD2-CB 3.8Å; L114-F305 HydrophobicContact CB-CD1 4.21Å; L114-F305 HydrophobicContact CB-CG 4.38Å; L114-F305 HydrophobicContact CD1-CB 4.46Å; L114-F305 HydrophobicContact CD1-CD2 4.14Å; L114-F305 HydrophobicContact CD1-CG 4.19Å; L114-F305 HydrophobicContact CD2-CB 4.07Å
115T93.5Very high92.1Very high0 Ų039.7 Ų39.70%019%0.192CC..G310 helixtrans-74.6-13.6176.363.90000113.6F106 H107 N108 D112 P113 H117 N120 M241 M242F106-T115 HydrophobicContact CE1-CG2 4.48Å; H107-T115 WeakPolarHBondContact CA-OG1 3.46Å; H107-T115 WeakPolarHBondContact CB-O 3.5Å; N108-T115 PolarHBondContact N-OG1 2.99Å; D112-T115 HydrophobicContact CB-CG2 4.09Å; D112-T115 WeakPolarHBondContact O-CB 3.3Å; D112-T115 PolarHBondContact O-N 3.49Å; D112-T115 PolarHBondContact O-OG1 3.46Å; D112-T115 WeakPolarHBondContact OD2-CG2 3.33Å; P113-T115 PolarHBondContact O-N 3.11Å; T115-H117 PolarHBondContact O-N 3.33Å; T115-H117 VanDerWaalsContact O-N 3.08Å; T115-N120 WeakPolarHBondContact O-CB 3.33Å; T115-N120 PolarHBondContact O-ND2 3.41Å; T115-M241 HydrophobicContact CG2-CB 4.26Å; T115-M241 HydrophobicContact CG2-CE 4.04Å; T115-M242 HydrophobicContact CG2-CG 4.25Å
116Q92.8Very high92.4Very high27 Ų2738.7 Ų38.713%0.12619%0.186CC..  trans-83.944.5176.6-77.4-164.7-17.200113.3G109 P113 L114 L121 Q303G109-Q116 VanDerWaalsContact CA-CG 3.47Å; G109-Q116 VanDerWaalsContact CA-NE2 3.32Å; P113-Q116 WeakPolarHBondContact O-CB 3.47Å; P113-Q116 PolarHBondContact O-N 2.94Å; L114-Q116 VanDerWaalsContact C-N 3.27Å; L114-Q116 PolarHBondContact O-N 3.16Å; Q116-L121 HydrophobicContact CB-CD2 4.14Å; Q116-L121 HydrophobicContact CG-CD2 4.27Å; Q116-Q303 PolarHBondContact O-NE2 3.37Å
117H94.3Very high92.6Very high15 Ų1543 Ų437%0.06921%0.205CC..SBendtrans-97.1158.9177.962.451.3000112.5L114 T115 F119 N120 L121 A302 F305 V306L114-H117 PolarHBondContact O-CD2 2.88Å; T115-H117 PolarHBondContact O-N 3.33Å; T115-H117 VanDerWaalsContact O-N 3.08Å; H117-F119 PolarHBondContact ND1-N 2.65Å; H117-F119 PolarHBondContact O-N 3.43Å; H117-N120 PolarHBondContact CE1-ND2 3.44Å; H117-N120 PolarHBondContact ND1-N 2.96Å; H117-N120 PolarHBondContact NE2-ND2 3.09Å; H117-N120 PolarHBondContact O-N 3.4Å; H117-L121 WeakPolarHBondContact O-CG 3.37Å; H117-L121 PolarHBondContact O-N 3.44Å; H117-L121 VanDerWaalsContact O-N 3.13Å; H117-A302 HydrophobicContact CB-CB 4.05Å; H117-A302 VanDerWaalsContact CB-O 3.25Å; H117-A302 WeakPolarHBondContact CB-O 3.4Å; H117-F305 AromaticContact CD2-CD1 3.93Å; H117-V306 HydrophobicContact CB-CB 3.63Å; H117-V306 HydrophobicContact CB-CG1 3.71Å; H117-V306 HydrophobicContact CB-CG2 4.21Å
118L95.4Very high92.7Very high12 Ų1241 Ų416%0.06320%0.196CC..THydrogen-bonded Turntrans-44.2-37.2-176.8-179.567.7000114.4M129 R130 L133 F307 I452L118-M129 HydrophobicContact CB-CG 4.25Å; L118-M129 HydrophobicContact CD1-CB 4.07Å; L118-M129 HydrophobicContact CD1-CG 3.9Å; L118-R130 HydrophobicContact CD1-CB 3.89Å; L118-L133 HydrophobicContact CB-CD1 4.13Å; L118-L133 HydrophobicContact CD1-CD1 4.39Å; L118-L133 HydrophobicContact CD2-CD1 3.92Å; L118-L133 HydrophobicContact CG-CD1 4.36Å; L118-F307 HydrophobicContact CD2-CZ 4.5Å; L118-I452 HydrophobicContact CD2-CB 4.31Å; L118-I452 HydrophobicContact CD2-CD1 3.89Å; L118-I452 HydrophobicContact CD2-CG2 4.01Å
119F94.8Very high92.8Very high93 Ų9340.8 Ų40.841%0.40820%0.195SC..THydrogen-bonded Turntrans-66.1-36.8-179.8-177-77.7000113.7R103 H117 V306R103-F119 PolarHBondContact NH1-O 3Å; H117-F119 PolarHBondContact ND1-N 2.65Å; H117-F119 PolarHBondContact O-N 3.43Å; F119-V306 HydrophobicContact CB-CG2 4.2Å
120N94.1Very high93.1Very high8 Ų841.8 Ų41.84%0.04319%0.194CC..THydrogen-bonded Turntrans-97.5-25.3-174.2-76.1-12.2000114Q105 F106 H107 T115 H117Q105-N120 HydrophobicContact CB-CB 4.42Å; F106-N120 PolarHBondContact O-ND2 2.87Å; H107-N120 HydrophobicContact CB-CB 4.25Å; T115-N120 WeakPolarHBondContact O-CB 3.33Å; T115-N120 PolarHBondContact O-ND2 3.41Å; H117-N120 PolarHBondContact CE1-ND2 3.44Å; H117-N120 PolarHBondContact ND1-N 2.96Å; H117-N120 PolarHBondContact NE2-ND2 3.09Å; H117-N120 PolarHBondContact O-N 3.4Å
121L94.7Very high93.2Very high3 Ų336 Ų362%0.01617%0.174CC..  trans-58.5150.6-179.8-70.7174.6000111.1Q116 H117 K125 W126 M129 R449Q116-L121 HydrophobicContact CB-CD2 4.14Å; Q116-L121 HydrophobicContact CG-CD2 4.27Å; H117-L121 WeakPolarHBondContact O-CG 3.37Å; H117-L121 PolarHBondContact O-N 3.44Å; H117-L121 VanDerWaalsContact O-N 3.13Å; L121-K125 HydrophobicContact CD2-CB 4.31Å; L121-K125 HydrophobicContact CD2-CD 4.49Å; L121-W126 HydrophobicContact CB-CB 4.03Å; L121-W126 WeakPolarHBondContact O-CB 3.37Å; L121-M129 HydrophobicContact CD1-CB 3.98Å; L121-M129 HydrophobicContact CD1-CE 4.4Å; L121-M129 HydrophobicContact CD1-CG 4.06Å; L121-R449 PolarHBondContact O-NH1 3.5Å; L121-R449 PolarHBondContact O-NH2 3.04Å
122D94.7Very high93Very high30 Ų3035.4 Ų35.416%0.1617%0.169CC..  trans-130.1169.1177.7-83.4-24.1000111.4D102 R103 G104 K125 W126 R449D102-D122 VanDerWaalsContact CA-OD1 3.29Å; D102-D122 WeakPolarHBondContact CA-OD1 3.5Å; D102-D122 HydrophobicContact CB-CB 4.18Å; D102-D122 WeakPolarHBondContact CB-OD1 3.41Å; D102-D122 WeakPolarHBondContact OD1-CB 3.47Å; R103-D122 PolarHBondContact N-OD1 2.71Å; G104-D122 WeakPolarHBondContact CA-OD2 3.37Å; G104-D122 PolarHBondContact N-OD2 2.89Å; D122-K125 PolarHBondContact O-N 3.2Å; D122-W126 PolarHBondContact O-N 2.64Å; D122-R449 IonicContact OD1-CZ 3.98Å; D122-R449 IonicContact OD1-NH1 3.12Å; D122-R449 PolarHBondContact OD1-NH1 3.17Å; D122-R449 IonicContact OD1-NH2 2.64Å; D122-R449 PolarHBondContact OD1-NH2 2.91Å; D122-R449 VanDerWaalsContact OD1-NH2 3.17Å
123G94Very high92.8Very high34 Ų3435.4 Ų35.435%0.35117%0.169SC..Hα-helixtrans55.8-140.2176.400000114D102 K125 W126 K127D102-G123 PolarHBondContact OD1-N 2.9Å; G123-K125 VanDerWaalsContact C-N 3.29Å; G123-K125 PolarHBondContact O-N 3.5Å; G123-W126 PolarHBondContact O-N 2.78Å; G123-K127 PolarHBondContact O-N 3.34Å; G123-K127 VanDerWaalsContact O-N 3.14Å
124K92.5Very high92.7Very high132 Ų13237.4 Ų37.457%0.57418%0.181SC*.Hα-helixtrans-58.2-39.5-178.7-170.2-178.2-172-55.40112.5W126 K127 D128K124-W126 VanDerWaalsContact C-N 3.33Å; K124-W126 PolarHBondContact O-N 2.64Å; K124-K127 PolarHBondContact O-N 3.11Å; K124-D128 IonicContact NZ-OD1 2.96Å; K124-D128 PolarHBondContact NZ-OD1 3.05Å; K124-D128 IonicContact NZ-OD2 2.66Å; K124-D128 PolarHBondContact NZ-OD2 2.97Å; K124-D128 WeakPolarHBondContact O-CB 3.47Å; K124-D128 PolarHBondContact O-N 3.19Å
125K91.8Very high92.3Very high112 Ų11240.8 Ų40.849%0.48720%0.203SC..Hα-helixtrans-60.8-42.4179.9-69-167.4172.5-158.10112L121 D122 G123 M129L121-K125 HydrophobicContact CD2-CB 4.31Å; L121-K125 HydrophobicContact CD2-CD 4.49Å; D122-K125 PolarHBondContact O-N 3.2Å; G123-K125 VanDerWaalsContact C-N 3.29Å; G123-K125 PolarHBondContact O-N 3.5Å; K125-M129 VanDerWaalsContact O-CB 3.22Å; K125-M129 WeakPolarHBondContact O-CB 3.36Å; K125-M129 PolarHBondContact O-N 2.65Å
126W95.1Very high91.8Very high16 Ų1641.5 Ų41.56%0.06121%0.207CC..Hα-helixtrans-63.4-47.4174170.378.2000112F97 L121 D122 G123 K124 D128 M129 R130 P448 R449F97-W126 AromaticContact CE1-CH2 3.91Å; F97-W126 HydrophobicContact CE1-CH2 3.91Å; F97-W126 AromaticContact CE1-CZ3 3.96Å; F97-W126 HydrophobicContact CE1-CZ3 3.96Å; F97-W126 AromaticContact CZ-CH2 3.47Å; F97-W126 HydrophobicContact CZ-CH2 3.47Å; F97-W126 VanDerWaalsContact CZ-CH2 3.47Å; F97-W126 HydrophobicContact CZ-CZ2 4.33Å; F97-W126 AromaticContact CZ-CZ3 3.73Å; F97-W126 HydrophobicContact CZ-CZ3 3.73Å; L121-W126 HydrophobicContact CB-CB 4.03Å; L121-W126 WeakPolarHBondContact O-CB 3.37Å; D122-W126 PolarHBondContact O-N 2.64Å; G123-W126 PolarHBondContact O-N 2.78Å; K124-W126 VanDerWaalsContact C-N 3.33Å; K124-W126 PolarHBondContact O-N 2.64Å; W126-D128 PolarHBondContact O-N 2.83Å; W126-M129 PolarHBondContact O-N 3.38Å; W126-R130 HydrophobicContact CZ2-CB 4.29Å; W126-R130 HydrophobicContact CZ2-CG 4.16Å; W126-R130 VanDerWaalsContact O-CB 3.3Å; W126-R130 WeakPolarHBondContact O-CB 3.19Å; W126-R130 PolarHBondContact O-N 3.07Å; W126-P448 HydrophobicContact CH2-CB 4.45Å; W126-R449 VanDerWaalsContact CD1-CZ 3.48Å; W126-R449 VanDerWaalsContact CE2-CD 3.45Å; W126-R449 HydrophobicContact CH2-CB 4.08Å; W126-R449 HydrophobicContact CH2-CG 4.32Å; W126-R449 HydrophobicContact CZ2-CB 3.57Å; W126-R449 HydrophobicContact CZ2-CG 3.45Å; W126-R449 VanDerWaalsContact CZ2-CG 3.45Å
127K93.8Very high91.6Very high95 Ų9541.2 Ų41.241%0.41321%0.206SC..Hα-helixtrans-58.7-50.8-179.4-174.8-172.6174.7-163.10111G123 K124 M129 R130 Q131G123-K127 PolarHBondContact O-N 3.34Å; G123-K127 VanDerWaalsContact O-N 3.14Å; K124-K127 PolarHBondContact O-N 3.11Å; K127-M129 PolarHBondContact O-N 3.45Å; K127-R130 PolarHBondContact O-N 3.01Å; K127-Q131 WeakPolarHBondContact O-CG 3.49Å; K127-Q131 PolarHBondContact O-N 3.46Å
128D90.8Very high91.4Very high18 Ų1843.2 Ų43.210%0.09622%0.219CC..Hα-helixtrans-59.2-48.3178.4-65.6-4.5000110.5K124 W126 R130 Q131 R132 I292K124-D128 IonicContact NZ-OD1 2.96Å; K124-D128 PolarHBondContact NZ-OD1 3.05Å; K124-D128 IonicContact NZ-OD2 2.66Å; K124-D128 PolarHBondContact NZ-OD2 2.97Å; K124-D128 WeakPolarHBondContact O-CB 3.47Å; K124-D128 PolarHBondContact O-N 3.19Å; W126-D128 PolarHBondContact O-N 2.83Å; D128-R130 PolarHBondContact O-N 3.21Å; D128-Q131 PolarHBondContact O-N 3.02Å; D128-R132 VanDerWaalsContact O-CG 3.29Å; D128-R132 WeakPolarHBondContact O-CG 3.35Å; D128-R132 PolarHBondContact O-N 3.46Å; D128-I292 HydrophobicContact CB-CD1 4.16Å; D128-I292 HydrophobicContact CB-CG2 4.22Å
129M91.3Very high91Very high4 Ų445.6 Ų45.62%0.0224%0.236CC..Hα-helixtrans-63.6-41.2179.5-171.759.372.500111.9L118 L121 K125 W126 K127 Q131 R132 L133 M295 Q303L118-M129 HydrophobicContact CB-CG 4.25Å; L118-M129 HydrophobicContact CD1-CB 4.07Å; L118-M129 HydrophobicContact CD1-CG 3.9Å; L121-M129 HydrophobicContact CD1-CB 3.98Å; L121-M129 HydrophobicContact CD1-CE 4.4Å; L121-M129 HydrophobicContact CD1-CG 4.06Å; K125-M129 VanDerWaalsContact O-CB 3.22Å; K125-M129 WeakPolarHBondContact O-CB 3.36Å; K125-M129 PolarHBondContact O-N 2.65Å; W126-M129 PolarHBondContact O-N 3.38Å; K127-M129 PolarHBondContact O-N 3.45Å; M129-Q131 VanDerWaalsContact C-N 3.34Å; M129-Q131 PolarHBondContact O-N 3.34Å; M129-R132 PolarHBondContact O-N 3.27Å; M129-L133 HydrophobicContact CG-CD1 3.72Å; M129-L133 HydrophobicContact CG-CG 4.43Å; M129-L133 VanDerWaalsContact O-CG 3.26Å; M129-L133 WeakPolarHBondContact O-CG 3.34Å; M129-L133 PolarHBondContact O-N 2.99Å; M129-L133 VanDerWaalsContact O-N 3.1Å; M129-L133 HydrophobicContact SD-CD1 3.79Å; M129-L133 HydrophobicContact SD-CG 4.09Å; M129-M295 HydrophobicContact CE-CG 4.33Å; M129-M295 HydrophobicContact CE-SD 3.84Å; M129-M295 HydrophobicContact SD-SD 4.03Å; M129-Q303 HydrophobicContact CE-CG 4.29Å; M129-Q303 HydrophobicContact SD-CG 3.89Å
130R94Very high90.7Very high39 Ų3943.6 Ų43.615%0.14724%0.242CC..Hα-helixtrans-61.6-43.9176.9-177.559.8-178.4-135.5-2.9111L118 W126 K127 D128 L133 T134 N450L118-R130 HydrophobicContact CD1-CB 3.89Å; W126-R130 HydrophobicContact CZ2-CB 4.29Å; W126-R130 HydrophobicContact CZ2-CG 4.16Å; W126-R130 VanDerWaalsContact O-CB 3.3Å; W126-R130 WeakPolarHBondContact O-CB 3.19Å; W126-R130 PolarHBondContact O-N 3.07Å; K127-R130 PolarHBondContact O-N 3.01Å; D128-R130 PolarHBondContact O-N 3.21Å; R130-L133 PolarHBondContact O-N 3.21Å; R130-T134 WeakPolarHBondContact O-CB 3.5Å; R130-T134 PolarHBondContact O-N 2.96Å; R130-T134 PolarHBondContact O-OG1 3.38Å; R130-N450 PolarHBondContact NH1-O 3.32Å; R130-N450 PolarHBondContact NH2-O 2.97Å; R130-N450 PolarHBondContact NH2-OD1 3.29Å
131Q90.1Very high90.4Very high55 Ų5548.2 Ų48.226%0.25726%0.262SS..Hα-helixtrans-63.4-44.6176.8-73.7171.5-35.500111.5K127 D128 M129 L133 P135 L286K127-Q131 WeakPolarHBondContact O-CG 3.49Å; K127-Q131 PolarHBondContact O-N 3.46Å; D128-Q131 PolarHBondContact O-N 3.02Å; M129-Q131 VanDerWaalsContact C-N 3.34Å; M129-Q131 PolarHBondContact O-N 3.34Å; Q131-L133 VanDerWaalsContact C-N 3.29Å; Q131-L133 PolarHBondContact O-N 2.82Å; Q131-P135 VanDerWaalsContact O-CD 3.27Å; Q131-P135 WeakPolarHBondContact O-CD 3.41Å; Q131-L286 HydrophobicContact CB-CD1 4.08Å; Q131-L286 HydrophobicContact CG-CD1 4.36Å; Q131-L286 VanDerWaalsContact OE1-CD1 3.25Å
132R85.6Confident90.2Very high26 Ų2648.2 Ų48.210%0.09826%0.262CS..Hα-helixtrans-58.6-38.2177.2-70175.3-158.2-175.45.6113.2D128 M129 L278 E293D128-R132 VanDerWaalsContact O-CG 3.29Å; D128-R132 WeakPolarHBondContact O-CG 3.35Å; D128-R132 PolarHBondContact O-N 3.46Å; M129-R132 PolarHBondContact O-N 3.27Å; R132-L278 HydrophobicContact CB-CD1 4.14Å; R132-E293 PolarHBondContact NH1-O 3.29Å; R132-E293 PolarHBondContact NH2-O 3.34Å
133L88.9Confident90Very high0 Ų052.4 Ų52.40%028%0.279CS..Hα-helixtrans-92.9-18.9-172.3-62.4171.1000114.1L118 M129 R130 Q131 P135 T136 F137 F271 L275 Q303 F307 I452L118-L133 HydrophobicContact CB-CD1 4.13Å; L118-L133 HydrophobicContact CD1-CD1 4.39Å; L118-L133 HydrophobicContact CD2-CD1 3.92Å; L118-L133 HydrophobicContact CG-CD1 4.36Å; M129-L133 HydrophobicContact CG-CD1 3.72Å; M129-L133 HydrophobicContact CG-CG 4.43Å; M129-L133 VanDerWaalsContact O-CG 3.26Å; M129-L133 WeakPolarHBondContact O-CG 3.34Å; M129-L133 PolarHBondContact O-N 2.99Å; M129-L133 VanDerWaalsContact O-N 3.1Å; M129-L133 HydrophobicContact SD-CD1 3.79Å; M129-L133 HydrophobicContact SD-CG 4.09Å; R130-L133 PolarHBondContact O-N 3.21Å; Q131-L133 VanDerWaalsContact C-N 3.29Å; Q131-L133 PolarHBondContact O-N 2.82Å; L133-P135 VanDerWaalsContact C-CD 3.48Å; L133-T136 WeakPolarHBondContact O-CB 3.38Å; L133-T136 PolarHBondContact O-N 2.78Å; L133-T136 PolarHBondContact O-OG1 3.47Å; L133-T136 VanDerWaalsContact O-OG1 3.05Å; L133-F137 WeakPolarHBondContact O-CD2 3.47Å; L133-F271 HydrophobicContact CD2-CE2 3.62Å; L133-F271 HydrophobicContact CD2-CZ 3.72Å; L133-L275 HydrophobicContact CD2-CD2 3.89Å; L133-Q303 HydrophobicContact CD1-CG 4.4Å; L133-F307 HydrophobicContact CD1-CE2 3.79Å; L133-F307 HydrophobicContact CD1-CZ 4.02Å; L133-F307 HydrophobicContact CD2-CE2 4.26Å; L133-I452 HydrophobicContact CB-CD1 3.72Å
134T90.1Very high89.6Confident66 Ų6656.1 Ų56.141%0.40529%0.285SS..G310 helixtrans-58.1-40.1-178.1-66.60000113.6R130 T136 F137R130-T134 WeakPolarHBondContact O-CB 3.5Å; R130-T134 PolarHBondContact O-N 2.96Å; R130-T134 PolarHBondContact O-OG1 3.38Å; T134-T136 PolarHBondContact O-N 3.18Å; T134-T136 VanDerWaalsContact O-N 3.11Å; T134-F137 PolarHBondContact O-N 2.96Å
135P86.3Confident89.5Confident71 Ų7151 Ų5146%0.46126%0.264SS..G310 helixtrans-57.2-26.6178-28.536.7000114.9Q131 L133 F137 T138 K141Q131-P135 VanDerWaalsContact O-CD 3.27Å; Q131-P135 WeakPolarHBondContact O-CD 3.41Å; L133-P135 VanDerWaalsContact C-CD 3.48Å; P135-F137 VanDerWaalsContact C-N 3.28Å; P135-F137 PolarHBondContact O-N 3.43Å; P135-T138 WeakPolarHBondContact O-CG2 3.47Å; P135-T138 PolarHBondContact O-OG1 2.98Å; P135-T138 VanDerWaalsContact O-OG1 3.11Å; P135-K141 WeakPolarHBondContact O-CG 3.39Å
136T83.8Confident89.6Confident15 Ų1546.3 Ų46.39%0.09224%0.244CC..G310 helixtrans-64.7-31.5177-410000112.5L133 T134 K141 M142 F271 L274L133-T136 WeakPolarHBondContact O-CB 3.38Å; L133-T136 PolarHBondContact O-N 2.78Å; L133-T136 PolarHBondContact O-OG1 3.47Å; L133-T136 VanDerWaalsContact O-OG1 3.05Å; T134-T136 PolarHBondContact O-N 3.18Å; T134-T136 VanDerWaalsContact O-N 3.11Å; T136-K141 WeakPolarHBondContact O-CB 3.34Å; T136-M142 WeakPolarHBondContact O-CE 3.34Å; T136-F271 HydrophobicContact CG2-CB 4.45Å; T136-F271 HydrophobicContact CG2-CD2 3.52Å; T136-F271 HydrophobicContact CG2-CE2 4.17Å; T136-F271 HydrophobicContact CG2-CG 4.37Å; T136-L274 HydrophobicContact CG2-CD2 4.35Å; T136-L274 WeakPolarHBondContact OG1-CD2 3.07Å
137F87.8Confident89.4Confident22 Ų2249.5 Ų49.510%0.09627%0.266CS..G310 helixtrans-103.420.4-170.4-62.4-79.9000113.3L133 T134 P135 M142 F307 I452 R455 F456L133-F137 WeakPolarHBondContact O-CD2 3.47Å; T134-F137 PolarHBondContact O-N 2.96Å; P135-F137 VanDerWaalsContact C-N 3.28Å; P135-F137 PolarHBondContact O-N 3.43Å; F137-M142 HydrophobicContact CD1-CE 4.21Å; F137-F307 HydrophobicContact CE1-CE1 4.25Å; F137-F307 HydrophobicContact CE2-CD1 4.3Å; F137-F307 AromaticContact CE2-CE1 3.4Å; F137-F307 HydrophobicContact CE2-CE1 3.4Å; F137-F307 AromaticContact CE2-CZ 3.7Å; F137-F307 HydrophobicContact CE2-CZ 3.7Å; F137-F307 AromaticContact CZ-CD1 3.67Å; F137-F307 HydrophobicContact CZ-CD1 3.67Å; F137-F307 AromaticContact CZ-CE1 3.17Å; F137-F307 HydrophobicContact CZ-CE1 3.17Å; F137-F307 AromaticContact CZ-CZ 3.93Å; F137-F307 HydrophobicContact CZ-CZ 3.93Å; F137-I452 WeakPolarHBondContact CB-O 3.15Å; F137-I452 HydrophobicContact CD2-CB 4.49Å; F137-I452 HydrophobicContact CD2-CD1 3.82Å; F137-I452 HydrophobicContact CD2-CG1 3.66Å; F137-I452 HydrophobicContact CD2-CG2 4.31Å; F137-I452 HydrophobicContact CE2-CD1 4.13Å; F137-I452 HydrophobicContact CE2-CG1 4.23Å; F137-I452 HydrophobicContact CE2-CG2 4.12Å; F137-I452 HydrophobicContact CG-CG1 4.26Å; F137-I452 WeakPolarHBondContact CG-O 3.29Å; F137-R455 PolarHBondContact O-NH1 3.31Å; F137-F456 HydrophobicContact CD1-CB 4.28Å; F137-F456 HydrophobicContact CE1-CB 4.3Å
138T89.3Confident89.4Confident56 Ų5647 Ų4734%0.34426%0.259SS..SBendtrans-72.2155.917558.10000111.6P135 G140 K141 M142P135-T138 WeakPolarHBondContact O-CG2 3.47Å; P135-T138 PolarHBondContact O-OG1 2.98Å; P135-T138 VanDerWaalsContact O-OG1 3.11Å; T138-G140 PolarHBondContact O-N 3.5Å; T138-K141 PolarHBondContact O-N 2.89Å; T138-K141 WeakPolarHBondContact OG1-CG 3.26Å; T138-M142 WeakPolarHBondContact O-CG 3.14Å; T138-M142 PolarHBondContact O-N 3.46Å
139S88.4Confident89.5Confident62 Ų6246.2 Ų46.243%0.43426%0.255SS..Hα-helixtrans-57.8-36.6178.7-51.40000112.6M142 K143S139-M142 PolarHBondContact O-N 3.2Å; S139-K143 PolarHBondContact O-N 2.83Å
140G88.1Confident89.8Confident52 Ų5247 Ų4754%0.53626%0.259SS..Hα-helixtrans-62.7-41.8175.100000112.7T138 K143 F144T138-G140 PolarHBondContact O-N 3.5Å; G140-K143 PolarHBondContact O-N 2.84Å; G140-F144 WeakPolarHBondContact O-CB 3.32Å; G140-F144 PolarHBondContact O-N 3.4Å
141K86.9Confident89.8Confident105 Ų10551.8 Ų51.846%0.45728%0.281SS..Hα-helixtrans-70-33.3174.8-68.1-64.4-176.9179.70112.7P135 T136 T138 F144 M145P135-K141 WeakPolarHBondContact O-CG 3.39Å; T136-K141 WeakPolarHBondContact O-CB 3.34Å; T138-K141 PolarHBondContact O-N 2.89Å; T138-K141 WeakPolarHBondContact OG1-CG 3.26Å; K141-F144 PolarHBondContact O-N 3.43Å; K141-M145 WeakPolarHBondContact O-CG 3.13Å; K141-M145 PolarHBondContact O-N 3.07Å
142M90.9Very high90.1Very high2 Ų249.9 Ų49.91%0.0127%0.273CS..Hα-helixtrans-62.6-50.4172.3-63-53.79500110.8T136 F137 T138 S139 F144 M145 F146 Y353 R455 F456 M459T136-M142 WeakPolarHBondContact O-CE 3.34Å; F137-M142 HydrophobicContact CD1-CE 4.21Å; T138-M142 WeakPolarHBondContact O-CG 3.14Å; T138-M142 PolarHBondContact O-N 3.46Å; S139-M142 PolarHBondContact O-N 3.2Å; M142-F144 PolarHBondContact O-N 3.41Å; M142-M145 HydrophobicContact CE-CE 3.14Å; M142-M145 PolarHBondContact O-N 3.27Å; M142-M145 VanDerWaalsContact O-N 3.1Å; M142-M145 HydrophobicContact SD-CE 4.1Å; M142-F146 PolarHBondContact O-N 2.94Å; M142-Y353 HydrophobicContact CB-CE2 4.14Å; M142-R455 HydrophobicContact CG-CB 4Å; M142-R455 HydrophobicContact SD-CB 4.1Å; M142-F456 HydrophobicContact SD-CB 3.84Å; M142-F456 HydrophobicContact SD-CD2 4.28Å; M142-M459 HydrophobicContact CB-SD 4.23Å; M142-M459 HydrophobicContact SD-CE 4.2Å
143K90Very high90.6Very high118 Ų11848.6 Ų48.651%0.51327%0.268SS..Hα-helixtrans-58.4-36.1176.8-171.7170.4-176.6165.30112.1S139 G140 F146 Y353S139-K143 PolarHBondContact O-N 2.83Å; G140-K143 PolarHBondContact O-N 2.84Å; K143-F146 WeakPolarHBondContact O-CB 3.3Å; K143-Y353 HydrophobicContact CB-CD2 4.24Å; K143-Y353 HydrophobicContact CB-CE2 4.29Å; K143-Y353 HydrophobicContact CB-CG 4.47Å; K143-Y353 HydrophobicContact CG-CD2 4.42Å; K143-Y353 HydrophobicContact CG-CG 4.26Å
144F87.1Confident90.9Very high113 Ų11353.3 Ų53.350%0.49629%0.29SS..Hα-helixtrans-67.8-40.5175-179.3-94.9000113.4G140 K141 M142 F146 P147 N269G140-F144 WeakPolarHBondContact O-CB 3.32Å; G140-F144 PolarHBondContact O-N 3.4Å; K141-F144 PolarHBondContact O-N 3.43Å; M142-F144 PolarHBondContact O-N 3.41Å; F144-F146 VanDerWaalsContact C-N 3.33Å; F144-P147 WeakPolarHBondContact O-CD 3.26Å; F144-N269 HydrophobicContact CE1-CB 3.84Å; F144-N269 WeakPolarHBondContact CE1-O 3.19Å; F144-N269 HydrophobicContact CZ-CB 3.78Å
145M90Very high91.1Very high24 Ų2452.6 Ų52.612%0.11828%0.282CS..Hα-helixtrans-76.6-21177.8-71.8-172.7-71.400113.1K141 M142 T148 V149 C190 F456 M459K141-M145 WeakPolarHBondContact O-CG 3.13Å; K141-M145 PolarHBondContact O-N 3.07Å; M142-M145 HydrophobicContact CE-CE 3.14Å; M142-M145 PolarHBondContact O-N 3.27Å; M142-M145 VanDerWaalsContact O-N 3.1Å; M142-M145 HydrophobicContact SD-CE 4.1Å; M145-T148 VanDerWaalsContact O-CB 3.29Å; M145-T148 WeakPolarHBondContact O-CB 3.49Å; M145-T148 PolarHBondContact O-N 3.46Å; M145-V149 PolarHBondContact O-N 3Å; M145-C190 HydrophobicContact SD-CB 3.98Å; M145-F456 HydrophobicContact CE-CD2 3.89Å; M145-F456 HydrophobicContact CE-CE2 4.23Å; M145-F456 HydrophobicContact SD-CD2 4.44Å; M145-F456 HydrophobicContact SD-CE2 4.18Å; M145-M459 HydrophobicContact CB-CE 4.44Å
146F92.6Very high91.6Very high14 Ų1449.2 Ų49.26%0.06126%0.26CS..Hα-helixtrans-50-47.4-174.6-173.9-87.9000114.2M142 K143 F144 T148 V149 I150 L351 T352 Y353 I356 M459 I463M142-F146 PolarHBondContact O-N 2.94Å; K143-F146 WeakPolarHBondContact O-CB 3.3Å; F144-F146 VanDerWaalsContact C-N 3.33Å; F146-T148 PolarHBondContact O-N 3.03Å; F146-V149 PolarHBondContact O-N 3.42Å; F146-I150 HydrophobicContact CD1-CG1 3.79Å; F146-I150 HydrophobicContact CE1-CD1 3.73Å; F146-I150 HydrophobicContact CE1-CG1 3.4Å; F146-I150 VanDerWaalsContact CE1-CG1 3.4Å; F146-I150 HydrophobicContact CZ-CD1 3.74Å; F146-I150 HydrophobicContact CZ-CG1 3.94Å; F146-I150 WeakPolarHBondContact O-CG1 3.34Å; F146-I150 PolarHBondContact O-N 3.47Å; F146-L351 VanDerWaalsContact CE1-O 3.22Å; F146-L351 WeakPolarHBondContact CE1-O 3.48Å; F146-T352 VanDerWaalsContact CE1-C 3.48Å; F146-T352 WeakPolarHBondContact CZ-O 3.48Å; F146-Y353 HydrophobicContact CB-CD2 4.14Å; F146-Y353 AromaticContact CD2-CD2 3.61Å; F146-Y353 HydrophobicContact CD2-CD2 3.61Å; F146-Y353 HydrophobicContact CD2-CE2 4.47Å; F146-Y353 HydrophobicContact CD2-CG 4.41Å; F146-Y353 HydrophobicContact CE2-CD2 4.21Å; F146-Y353 AromaticContact CG-CD2 3.98Å; F146-Y353 HydrophobicContact CG-CD2 3.98Å; F146-I356 HydrophobicContact CE2-CB 4.45Å; F146-I356 HydrophobicContact CE2-CG1 4.1Å; F146-I356 HydrophobicContact CZ-CG1 4.16Å; F146-M459 HydrophobicContact CB-SD 4.19Å; F146-M459 HydrophobicContact CD2-CG 4.09Å; F146-M459 HydrophobicContact CD2-SD 3.84Å; F146-I463 HydrophobicContact CD2-CD1 3.87Å; F146-I463 HydrophobicContact CE2-CD1 3.59Å; F146-I463 HydrophobicContact CE2-CG1 4.06Å; F146-I463 HydrophobicContact CZ-CD1 4.24Å
147P92.7Very high92.2Very high82 Ų8249.2 Ų49.253%0.53226%0.26SS..Hα-helixtrans-60.9-31.3178-23.135.1000113.7F144 I150 K151F144-P147 WeakPolarHBondContact O-CD 3.26Å; P147-I150 PolarHBondContact O-N 2.96Å; P147-K151 PolarHBondContact O-N 3.4Å
148T92.1Very high92.5Very high44 Ų4453.1 Ų53.127%0.2728%0.277SS..Hα-helixtrans-68-42.3175.8-57.50000110.6M145 F146 I150 K151 V152 T189 C190M145-T148 VanDerWaalsContact O-CB 3.29Å; M145-T148 WeakPolarHBondContact O-CB 3.49Å; M145-T148 PolarHBondContact O-N 3.46Å; F146-T148 PolarHBondContact O-N 3.03Å; T148-I150 VanDerWaalsContact C-N 3.33Å; T148-K151 PolarHBondContact O-N 3.44Å; T148-V152 WeakPolarHBondContact O-CG2 3.36Å; T148-V152 PolarHBondContact O-N 3.38Å; T148-V152 VanDerWaalsContact O-N 3.13Å; T148-T189 HydrophobicContact CG2-CG2 3.37Å; T148-C190 VanDerWaalsContact CG2-SG 3.56Å
149V94.8Very high92.8Very high0 Ų050.7 Ų50.70%026%0.262CS..Hα-helixtrans-65.2-39.6176.4-171.30000110.8M145 F146 V152 S153 V186 M459 Q460 I463M145-V149 PolarHBondContact O-N 3Å; F146-V149 PolarHBondContact O-N 3.42Å; V149-V152 PolarHBondContact O-N 3.5Å; V149-S153 WeakPolarHBondContact O-CB 3.4Å; V149-S153 PolarHBondContact O-N 2.77Å; V149-V186 HydrophobicContact CG1-CG1 4.23Å; V149-V186 HydrophobicContact CG1-CG2 4.06Å; V149-V186 HydrophobicContact CG2-CG1 4.11Å; V149-M459 HydrophobicContact CG2-CE 3.98Å; V149-Q460 HydrophobicContact CG1-CB 4.31Å; V149-I463 HydrophobicContact CB-CD1 3.92Å; V149-I463 HydrophobicContact CG1-CB 4.42Å; V149-I463 HydrophobicContact CG1-CD1 3.54Å; V149-I463 HydrophobicContact CG1-CG2 4.31Å
150I95.6Very high93.1Very high22 Ų2247.9 Ų47.911%0.11324%0.242CC..Hα-helixtrans-59.5-49.1174.2-67-58.5000111.1F146 P147 T148 V152 S153 E154 L351 I463F146-I150 HydrophobicContact CD1-CG1 3.79Å; F146-I150 HydrophobicContact CE1-CD1 3.73Å; F146-I150 HydrophobicContact CE1-CG1 3.4Å; F146-I150 VanDerWaalsContact CE1-CG1 3.4Å; F146-I150 HydrophobicContact CZ-CD1 3.74Å; F146-I150 HydrophobicContact CZ-CG1 3.94Å; F146-I150 WeakPolarHBondContact O-CG1 3.34Å; F146-I150 PolarHBondContact O-N 3.47Å; P147-I150 PolarHBondContact O-N 2.96Å; T148-I150 VanDerWaalsContact C-N 3.33Å; I150-V152 VanDerWaalsContact C-N 3.32Å; I150-V152 PolarHBondContact O-N 2.86Å; I150-S153 WeakPolarHBondContact CA-OG 3.49Å; I150-S153 CarbonylContact O-C 3.51Å; I150-S153 WeakPolarHBondContact O-CA 3.34Å; I150-S153 WeakPolarHBondContact O-CB 3.39Å; I150-S153 PolarHBondContact O-N 3.29Å; I150-S153 PolarHBondContact O-OG 3.03Å; I150-E154 HydrophobicContact CG2-CG 4.35Å; I150-E154 WeakPolarHBondContact O-CG 3.49Å; I150-E154 PolarHBondContact O-N 2.59Å; I150-L351 HydrophobicContact CD1-CB 3.78Å; I150-I463 HydrophobicContact CD1-CD1 4.18Å; I150-I463 HydrophobicContact CD1-CG1 4.27Å; I150-I463 HydrophobicContact CD1-CG2 3.98Å
151K94.5Very high93.4Very high138 Ų13847.4 Ų47.460%0.623%0.229SC*.Hα-helixtrans-55.8-44.7177.3-176.7-178.3176.7-170.50112.4P147 T148 S153 E154 E155P147-K151 PolarHBondContact O-N 3.4Å; T148-K151 PolarHBondContact O-N 3.44Å; K151-S153 VanDerWaalsContact C-N 3.29Å; K151-S153 PolarHBondContact O-N 3.03Å; K151-E154 PolarHBondContact O-N 3.4Å; K151-E155 PolarHBondContact O-N 3.36Å
152V96.1Very high93.6Very high15 Ų1548.1 Ų48.19%0.09123%0.234CC..Hα-helixtrans-65.1-37.1175.7178.90000110.8T148 V149 I150 E155 F156 F182 D185 V186 L199T148-V152 WeakPolarHBondContact O-CG2 3.36Å; T148-V152 PolarHBondContact O-N 3.38Å; T148-V152 VanDerWaalsContact O-N 3.13Å; V149-V152 PolarHBondContact O-N 3.5Å; I150-V152 VanDerWaalsContact C-N 3.32Å; I150-V152 PolarHBondContact O-N 2.86Å; V152-E155 PolarHBondContact O-N 3.18Å; V152-F156 VanDerWaalsContact O-CB 3.32Å; V152-F156 WeakPolarHBondContact O-CB 3.21Å; V152-F156 PolarHBondContact O-N 3Å; V152-F182 HydrophobicContact CG1-CD2 3.92Å; V152-F182 HydrophobicContact CG1-CE2 3.98Å; V152-D185 HydrophobicContact CG1-CB 3.74Å; V152-V186 HydrophobicContact CB-CG2 4.05Å; V152-V186 HydrophobicContact CG1-CG2 3.74Å; V152-L199 HydrophobicContact CG1-CD1 4.09Å
153S96.1Very high93.6Very high0 Ų051.9 Ų51.90%025%0.251CS..Hα-helixtrans-70.4-30.2179.183.70000114V149 I150 K151 F156 V157 Q467V149-S153 WeakPolarHBondContact O-CB 3.4Å; V149-S153 PolarHBondContact O-N 2.77Å; I150-S153 WeakPolarHBondContact CA-OG 3.49Å; I150-S153 CarbonylContact O-C 3.51Å; I150-S153 WeakPolarHBondContact O-CA 3.34Å; I150-S153 WeakPolarHBondContact O-CB 3.39Å; I150-S153 PolarHBondContact O-N 3.29Å; I150-S153 PolarHBondContact O-OG 3.03Å; K151-S153 VanDerWaalsContact C-N 3.29Å; K151-S153 PolarHBondContact O-N 3.03Å; S153-F156 WeakPolarHBondContact O-CB 3.42Å; S153-F156 PolarHBondContact O-N 3.02Å; S153-V157 WeakPolarHBondContact O-CG2 3.3Å; S153-V157 PolarHBondContact O-N 2.9Å; S153-Q467 PolarHBondContact OG-NE2 2.73Å
154E95.1Very high93.6Very high98 Ų9846.2 Ų46.246%0.45823%0.227SC..Hα-helixtrans-67.8-43.6172.6-70.4169.5173.500110.6I150 K151 F156 V157 K158I150-E154 HydrophobicContact CG2-CG 4.35Å; I150-E154 WeakPolarHBondContact O-CG 3.49Å; I150-E154 PolarHBondContact O-N 2.59Å; K151-E154 PolarHBondContact O-N 3.4Å; E154-F156 VanDerWaalsContact C-N 3.27Å; E154-F156 PolarHBondContact O-N 2.83Å; E154-V157 PolarHBondContact O-N 3.5Å; E154-K158 WeakPolarHBondContact O-CG 3.46Å; E154-K158 PolarHBondContact O-N 3.38Å
155E95.9Very high93.2Very high52 Ų5244.1 Ų44.124%0.24323%0.225CC..Hα-helixtrans-63.3-39174.6-167.958.2-157.100111.5K151 V152 K158 V159 R200K151-E155 PolarHBondContact O-N 3.36Å; V152-E155 PolarHBondContact O-N 3.18Å; E155-K158 WeakPolarHBondContact O-CB 3.5Å; E155-K158 PolarHBondContact O-N 3.13Å; E155-K158 IonicContact OE2-NZ 3.53Å; E155-K158 PolarHBondContact OE2-NZ 3.34Å; E155-V159 WeakPolarHBondContact O-CG2 3.25Å; E155-V159 PolarHBondContact O-N 2.94Å; E155-R200 IonicContact OE1-CZ 3.07Å; E155-R200 IonicContact OE1-NE 2.67Å; E155-R200 PolarHBondContact OE1-NE 2.92Å; E155-R200 IonicContact OE1-NH2 2.95Å; E155-R200 PolarHBondContact OE1-NH2 2.91Å
156F96.4Very high92.4Very high0 Ų047.2 Ų47.20%025%0.254CS..Hα-helixtrans-58.2-47.7174.1176.2-124.2000112.6V152 S153 E154 K158 V159 I160 L178 M179 F182 L199 I468V152-F156 VanDerWaalsContact O-CB 3.32Å; V152-F156 WeakPolarHBondContact O-CB 3.21Å; V152-F156 PolarHBondContact O-N 3Å; S153-F156 WeakPolarHBondContact O-CB 3.42Å; S153-F156 PolarHBondContact O-N 3.02Å; E154-F156 VanDerWaalsContact C-N 3.27Å; E154-F156 PolarHBondContact O-N 2.83Å; F156-K158 PolarHBondContact O-N 2.97Å; F156-V159 PolarHBondContact O-N 3.42Å; F156-I160 HydrophobicContact CD1-CD1 4.42Å; F156-I160 HydrophobicContact CD2-CD1 4.33Å; F156-I160 HydrophobicContact CD2-CG1 4.47Å; F156-I160 HydrophobicContact CE1-CD1 3.76Å; F156-I160 HydrophobicContact CE2-CD1 3.65Å; F156-I160 HydrophobicContact CE2-CG1 4Å; F156-I160 HydrophobicContact CZ-CD1 3.28Å; F156-I160 HydrophobicContact CZ-CG1 4.14Å; F156-I160 WeakPolarHBondContact O-CG1 3.49Å; F156-I160 PolarHBondContact O-N 3.23Å; F156-L178 HydrophobicContact CD2-CD1 4.37Å; F156-L178 HydrophobicContact CE2-CD1 3.61Å; F156-L178 HydrophobicContact CE2-CD2 4.21Å; F156-L178 HydrophobicContact CE2-CG 3.62Å; F156-L178 HydrophobicContact CZ-CD2 4.37Å; F156-L178 HydrophobicContact CZ-CG 4.12Å; F156-M179 HydrophobicContact CE1-CE 3.85Å; F156-M179 HydrophobicContact CE2-CE 3.89Å; F156-M179 HydrophobicContact CZ-CE 3.13Å; F156-F182 HydrophobicContact CB-CD2 3.77Å; F156-F182 HydrophobicContact CB-CE2 4.28Å; F156-F182 HydrophobicContact CD1-CD2 4.03Å; F156-F182 HydrophobicContact CD1-CE2 4.39Å; F156-F182 HydrophobicContact CD1-CG 4.23Å; F156-F182 HydrophobicContact CD2-CB 3.93Å; F156-F182 HydrophobicContact CD2-CD2 4.29Å; F156-F182 HydrophobicContact CD2-CG 4.31Å; F156-F182 HydrophobicContact CE2-CB 4.1Å; F156-F182 HydrophobicContact CG-CB 4.23Å; F156-F182 AromaticContact CG-CD2 3.76Å; F156-F182 HydrophobicContact CG-CD2 3.76Å; F156-F182 HydrophobicContact CG-CE2 4.43Å; F156-F182 HydrophobicContact CG-CG 4.1Å; F156-L199 HydrophobicContact CB-CD1 3.92Å; F156-L199 HydrophobicContact CD2-CD1 4.49Å; F156-L199 HydrophobicContact CD2-CD2 3.62Å; F156-L199 HydrophobicContact CE2-CD2 4.35Å; F156-I468 HydrophobicContact CE1-CD1 3.78Å; F156-I468 HydrophobicContact CE1-CG1 3.75Å; F156-I468 HydrophobicContact CZ-CD1 3.86Å; F156-I468 HydrophobicContact CZ-CG1 4.15Å
157V95.4Very high91.2Very high15 Ų1549.9 Ų49.99%0.09128%0.278CS..Hα-helixtrans-61.8-42.1175.3169.90000111.4S153 E154 V159 I160 T161 Q467 F472S153-V157 WeakPolarHBondContact O-CG2 3.3Å; S153-V157 PolarHBondContact O-N 2.9Å; E154-V157 PolarHBondContact O-N 3.5Å; V157-V159 VanDerWaalsContact C-N 3.35Å; V157-V159 PolarHBondContact O-N 3.06Å; V157-I160 PolarHBondContact O-N 3.04Å; V157-T161 VanDerWaalsContact O-CB 3.28Å; V157-T161 WeakPolarHBondContact O-CB 3.48Å; V157-T161 PolarHBondContact O-N 3.29Å; V157-T161 PolarHBondContact O-OG1 3.46Å; V157-Q467 HydrophobicContact CG2-CB 3.75Å; V157-Q467 HydrophobicContact CG2-CG 4.27Å; V157-F472 HydrophobicContact CG1-CE2 4.47Å
158K95.4Very high89.8Confident104 Ų10455.1 Ų55.145%0.45230%0.296SS..Hα-helixtrans-59.2-45.9176.5-69.4172.9-164.2165.50111.6E154 E155 F156 I160 T161 E162E154-K158 WeakPolarHBondContact O-CG 3.46Å; E154-K158 PolarHBondContact O-N 3.38Å; E155-K158 WeakPolarHBondContact O-CB 3.5Å; E155-K158 PolarHBondContact O-N 3.13Å; E155-K158 IonicContact OE2-NZ 3.53Å; E155-K158 PolarHBondContact OE2-NZ 3.34Å; F156-K158 PolarHBondContact O-N 2.97Å; K158-I160 PolarHBondContact O-N 3.44Å; K158-T161 WeakPolarHBondContact O-CB 3.33Å; K158-T161 PolarHBondContact O-N 3.44Å; K158-E162 VanDerWaalsContact O-CG 3.31Å; K158-E162 WeakPolarHBondContact O-CG 3.46Å; K158-E162 PolarHBondContact O-N 2.97Å
159V94.7Very high88.9Confident5 Ų558.5 Ų58.53%0.0331%0.312CS..Hα-helixtrans-62.4-42.8178.71690000111.9E155 F156 V157 T161 E162 Q163 L199 R200E155-V159 WeakPolarHBondContact O-CG2 3.25Å; E155-V159 PolarHBondContact O-N 2.94Å; F156-V159 PolarHBondContact O-N 3.42Å; V157-V159 VanDerWaalsContact C-N 3.35Å; V157-V159 PolarHBondContact O-N 3.06Å; V159-T161 VanDerWaalsContact C-N 3.34Å; V159-E162 PolarHBondContact O-N 2.96Å; V159-Q163 VanDerWaalsContact CG1-NE2 3.26Å; V159-Q163 WeakPolarHBondContact O-CG 3.48Å; V159-Q163 PolarHBondContact O-N 3.27Å; V159-Q163 VanDerWaalsContact O-N 3.15Å; V159-L199 WeakPolarHBondContact CG1-O 3.25Å; V159-L199 HydrophobicContact CG2-CB 4.35Å; V159-R200 HydrophobicContact CG2-CG 4.16Å
160I95Very high88.6Confident2 Ų259.5 Ų59.51%0.0132%0.322CS..Hα-helixtrans-63.6-45.1174.4-63.8176.5000110.2F156 V157 K158 E162 Q163 V164 L173 L178 I468 F472 V503F156-I160 HydrophobicContact CD1-CD1 4.42Å; F156-I160 HydrophobicContact CD2-CD1 4.33Å; F156-I160 HydrophobicContact CD2-CG1 4.47Å; F156-I160 HydrophobicContact CE1-CD1 3.76Å; F156-I160 HydrophobicContact CE2-CD1 3.65Å; F156-I160 HydrophobicContact CE2-CG1 4Å; F156-I160 HydrophobicContact CZ-CD1 3.28Å; F156-I160 HydrophobicContact CZ-CG1 4.14Å; F156-I160 WeakPolarHBondContact O-CG1 3.49Å; F156-I160 PolarHBondContact O-N 3.23Å; V157-I160 PolarHBondContact O-N 3.04Å; K158-I160 PolarHBondContact O-N 3.44Å; I160-E162 PolarHBondContact O-N 3.16Å; I160-Q163 CarbonylContact O-C 3.52Å; I160-Q163 PolarHBondContact O-N 3.14Å; I160-V164 HydrophobicContact CG2-CG2 3.8Å; I160-V164 WeakPolarHBondContact O-CB 3.48Å; I160-V164 WeakPolarHBondContact O-CG2 3.31Å; I160-V164 PolarHBondContact O-N 3.35Å; I160-L173 HydrophobicContact CG2-CD1 4.21Å; I160-L178 HydrophobicContact CD1-CD2 4Å; I160-L178 HydrophobicContact CG1-CD1 4.27Å; I160-L178 HydrophobicContact CG1-CD2 3.92Å; I160-I468 HydrophobicContact CD1-CD1 4.5Å; I160-I468 HydrophobicContact CD1-CG1 4.05Å; I160-F472 HydrophobicContact CB-CE1 4.44Å; I160-F472 HydrophobicContact CB-CE2 4.22Å; I160-F472 HydrophobicContact CB-CZ 3.89Å; I160-F472 HydrophobicContact CG2-CD1 4.04Å; I160-F472 HydrophobicContact CG2-CD2 4.29Å; I160-F472 HydrophobicContact CG2-CE1 3.51Å; I160-F472 HydrophobicContact CG2-CE2 3.82Å; I160-F472 HydrophobicContact CG2-CG 4.4Å; I160-F472 HydrophobicContact CG2-CZ 3.4Å; I160-V503 HydrophobicContact CG2-CG1 4.3Å
161T93.8Very high88.6Confident42 Ų4259.3 Ų59.326%0.25832%0.324SS..Hα-helixtrans-55.5-53178.4-58.40000109.1V157 K158 V159 Q163 V164 R505V157-T161 VanDerWaalsContact O-CB 3.28Å; V157-T161 WeakPolarHBondContact O-CB 3.48Å; V157-T161 PolarHBondContact O-N 3.29Å; V157-T161 PolarHBondContact O-OG1 3.46Å; K158-T161 WeakPolarHBondContact O-CB 3.33Å; K158-T161 PolarHBondContact O-N 3.44Å; V159-T161 VanDerWaalsContact C-N 3.34Å; T161-Q163 PolarHBondContact O-N 2.94Å; T161-Q163 VanDerWaalsContact O-N 3.15Å; T161-V164 CarbonylContact O-C 3.54Å; T161-V164 PolarHBondContact O-N 2.67Å; T161-V164 VanDerWaalsContact O-N 3.16Å; T161-R505 VanDerWaalsContact C-NH2 3.32Å; T161-R505 VanDerWaalsContact CG2-NH2 3.33Å; T161-R505 PolarHBondContact O-NH2 2.86Å
162E92.2Very high88.6Confident120 Ų12055.8 Ų55.856%0.56131%0.314SS*.Hα-helixtrans-54-35.3176.2-70.7166.6-15600113.4K158 V159 I160 R200K158-E162 VanDerWaalsContact O-CG 3.31Å; K158-E162 WeakPolarHBondContact O-CG 3.46Å; K158-E162 PolarHBondContact O-N 2.97Å; V159-E162 PolarHBondContact O-N 2.96Å; I160-E162 PolarHBondContact O-N 3.16Å; E162-R200 IonicContact OE1-CZ 3.64Å; E162-R200 IonicContact OE1-NH1 3.36Å; E162-R200 PolarHBondContact OE1-NH1 3.32Å; E162-R200 IonicContact OE1-NH2 3.79Å; E162-R200 PolarHBondContact OE1-NH2 3.14Å; E162-R200 IonicContact OE2-CZ 3.78Å; E162-R200 IonicContact OE2-NH1 2.89Å; E162-R200 PolarHBondContact OE2-NH1 3.44Å; E162-R200 IonicContact OE2-NH2 3.44Å
163Q90.2Very high88.6Confident81 Ų8155.7 Ų55.738%0.37931%0.313SS..Hα-helixtrans-84.4-24.3-179.8-70.1177.135.200114.8V159 I160 T161 P165 L173V159-Q163 VanDerWaalsContact CG1-NE2 3.26Å; V159-Q163 WeakPolarHBondContact O-CG 3.48Å; V159-Q163 PolarHBondContact O-N 3.27Å; V159-Q163 VanDerWaalsContact O-N 3.15Å; I160-Q163 CarbonylContact O-C 3.52Å; I160-Q163 PolarHBondContact O-N 3.14Å; T161-Q163 PolarHBondContact O-N 2.94Å; T161-Q163 VanDerWaalsContact O-N 3.15Å; Q163-P165 WeakPolarHBondContact O-CD 3.29Å; Q163-L173 HydrophobicContact CB-CD2 4.15Å
164V90.2Very high88.7Confident0 Ų057.8 Ų57.80%032%0.323CS..SBendtrans-105.7102.3-178.1-178.70000108.2I160 T161 A171 L173 F472 V503 R505I160-V164 HydrophobicContact CG2-CG2 3.8Å; I160-V164 WeakPolarHBondContact O-CB 3.48Å; I160-V164 WeakPolarHBondContact O-CG2 3.31Å; I160-V164 PolarHBondContact O-N 3.35Å; T161-V164 CarbonylContact O-C 3.54Å; T161-V164 PolarHBondContact O-N 2.67Å; T161-V164 VanDerWaalsContact O-N 3.16Å; V164-A171 HydrophobicContact CG2-CB 4.23Å; V164-L173 HydrophobicContact CG2-CD1 3.86Å; V164-L173 HydrophobicContact CG2-CG 4.45Å; V164-F472 HydrophobicContact CB-CE1 4.41Å; V164-V503 WeakPolarHBondContact CG1-O 3.27Å; V164-V503 HydrophobicContact CG2-CB 4.05Å; V164-V503 HydrophobicContact CG2-CG1 3.96Å; V164-R505 HydrophobicContact CB-CG 4.49Å; V164-R505 HydrophobicContact CG1-CG 3.99Å; V164-R505 PolarHBondContact O-NE 3Å; V164-R505 PolarHBondContact O-NH2 2.84Å
165P79.1Confident88.7Confident69 Ų6953.3 Ų53.345%0.44830%0.302SS..  trans-61.5154.4177.4-19.432.1000111.4Q163 A167Q163-P165 WeakPolarHBondContact O-CD 3.29Å; P165-A167 HydrophobicContact CB-CB 4.3Å; P165-A167 PolarHBondContact O-N 3.36Å; P165-A167 VanDerWaalsContact O-N 3.13Å
166A73.7Confident88.7Confident89 Ų8952.5 Ų52.574%0.73630%0.297SS*.SBendtrans-71.83.2171.700000113.6
167A66.6Low88.5Confident69 Ų6954.8 Ų54.857%0.5731%0.308SS*.SBendtrans-75.8160.7-179.800000112.1P165 N169 G170P165-A167 HydrophobicContact CB-CB 4.3Å; P165-A167 PolarHBondContact O-N 3.36Å; P165-A167 VanDerWaalsContact O-N 3.13Å; A167-N169 PolarHBondContact O-N 3.32Å; A167-G170 PolarHBondContact O-N 2.93Å
168Q62.1Low88.5Confident193 Ų19354.4 Ų54.490%0.90231%0.305SS*.THydrogen-bonded Turntrans-59.9-1-160.7-93176-16.200118.7
169N75.3Confident88.6Confident115 Ų11549.4 Ų49.462%0.61528%0.284SS*.THydrogen-bonded Turntrans-131.48.1-175.2-67.8-25.8000115A167 R502A167-N169 PolarHBondContact O-N 3.32Å; N169-R502 PolarHBondContact O-NH1 3.06Å
170G88.1Confident88.5Confident20 Ų2049.2 Ų49.221%0.20628%0.283CS..  trans59-154.1-177.500000113.5A167 V503A167-G170 PolarHBondContact O-N 2.93Å; G170-V503 CarbonylContact C-O 3.55Å; G170-V503 WeakPolarHBondContact CA-O 3.24Å
171A94.4Very high88.5Confident19 Ų1950.1 Ų50.116%0.15729%0.286CS..EExtended strand (participates in β ladder)trans-136.9150.1174.700000111.5V164 L173 V503V164-A171 HydrophobicContact CG2-CB 4.23Å; A171-L173 HydrophobicContact CB-CD2 4.22Å; A171-V503 PolarHBondContact N-O 3.45Å; A171-V503 PolarHBondContact O-N 2.96Å
172V95.8Very high88.6Confident63 Ų6348.1 Ų48.138%0.38227%0.274SS..EExtended strand (participates in β ladder)trans-85.1119170.5177.30000108.3C477 Y500 L501V172-C477 HydrophobicContact CG2-CB 4.15Å; V172-Y500 HydrophobicContact CG1-CD1 4.41Å; V172-L501 WeakPolarHBondContact CA-O 3.29Å
173L96.2Very high88.8Confident13 Ų1342.4 Ų42.47%0.06825%0.247CC..EExtended strand (participates in β ladder)trans-115.2144.9179.6-56.9-173.6000110.5I160 Q163 V164 A171 I175 L178 Y500 L501 V503I160-L173 HydrophobicContact CG2-CD1 4.21Å; Q163-L173 HydrophobicContact CB-CD2 4.15Å; V164-L173 HydrophobicContact CG2-CD1 3.86Å; V164-L173 HydrophobicContact CG2-CG 4.45Å; A171-L173 HydrophobicContact CB-CD2 4.22Å; L173-I175 HydrophobicContact CB-CD1 4.06Å; L173-I175 PolarHBondContact O-N 3.1Å; L173-L178 HydrophobicContact CD1-CD2 4.03Å; L173-Y500 WeakPolarHBondContact O-CA 3.28Å; L173-L501 PolarHBondContact N-O 3Å; L173-L501 PolarHBondContact O-N 3.03Å; L173-V503 HydrophobicContact CB-CG2 4.27Å; L173-V503 HydrophobicContact CD1-CB 4.14Å; L173-V503 HydrophobicContact CD1-CG2 3.92Å; L173-V503 HydrophobicContact CG-CB 4.4Å; L173-V503 HydrophobicContact CG-CG2 4.1Å
174E96.5Very high89Confident45 Ų4538.6 Ų38.621%0.2123%0.229CC..EExtended strand (participates in β ladder)trans-83.2100.2167.7-156-71.4127.100108.2K176 E177 L178 G498 I499 Y500E174-K176 WeakPolarHBondContact OE1-CB 3.27Å; E174-K176 PolarHBondContact OE1-N 3.05Å; E174-E177 VanDerWaalsContact OE2-CA 3.3Å; E174-E177 WeakPolarHBondContact OE2-CA 3.29Å; E174-E177 WeakPolarHBondContact OE2-CB 3.41Å; E174-E177 PolarHBondContact OE2-N 3.03Å; E174-L178 WeakPolarHBondContact O-CB 3.41Å; E174-L178 PolarHBondContact O-N 2.95Å; E174-G498 WeakPolarHBondContact OE1-CA 3.37Å; E174-I499 CarbonylContact C-O 3.57Å; E174-I499 PolarHBondContact OE1-N 3.03Å; E174-Y500 HydrophobicContact CB-CD1 3.87Å; E174-Y500 HydrophobicContact CB-CE1 3.57Å; E174-Y500 HydrophobicContact CG-CD1 3.9Å; E174-Y500 HydrophobicContact CG-CD2 4.42Å; E174-Y500 HydrophobicContact CG-CE1 3.42Å; E174-Y500 VanDerWaalsContact CG-CE1 3.42Å; E174-Y500 HydrophobicContact CG-CE2 3.98Å; E174-Y500 HydrophobicContact CG-CG 4.38Å; E174-Y500 VanDerWaalsContact CG-CZ 3.46Å
175I96.7Very high89.2Confident4 Ų439 Ų392%0.02123%0.231CC..Hα-helixtrans-70.5-34.2-168.4-60.9-62000111.4L173 L178 M179 L323 I499 L501 V503L173-I175 HydrophobicContact CB-CD1 4.06Å; L173-I175 PolarHBondContact O-N 3.1Å; I175-L178 HydrophobicContact CD1-CD2 4.44Å; I175-L178 PolarHBondContact O-N 3.44Å; I175-M179 HydrophobicContact CG2-CG 4Å; I175-M179 WeakPolarHBondContact O-CB 3.42Å; I175-M179 WeakPolarHBondContact O-CG 3.42Å; I175-M179 PolarHBondContact O-N 3.41Å; I175-L323 HydrophobicContact CG2-CB 4.22Å; I175-L323 HydrophobicContact CG2-CD1 3.52Å; I175-I499 HydrophobicContact CB-CG2 4.48Å; I175-I499 WeakPolarHBondContact CB-O 3.26Å; I175-I499 PolarHBondContact N-O 3.5Å; I175-L501 HydrophobicContact CD1-CB 4.33Å; I175-L501 HydrophobicContact CG1-CB 3.81Å; I175-L501 HydrophobicContact CG1-CD1 3.86Å; I175-L501 HydrophobicContact CG1-CG 3.88Å; I175-V503 HydrophobicContact CD1-CG2 3.96Å
176K94.3Very high89.9Confident35 Ų3535.7 Ų35.715%0.15221%0.21CC..Hα-helixtrans-66.4-44.8-176.8-170.2-177.7175.8-174.60111.9E174 M179 A180 S320 T495E174-K176 WeakPolarHBondContact OE1-CB 3.27Å; E174-K176 PolarHBondContact OE1-N 3.05Å; K176-M179 PolarHBondContact O-N 3.24Å; K176-A180 VanDerWaalsContact O-CB 3.26Å; K176-A180 WeakPolarHBondContact O-CB 3.12Å; K176-A180 PolarHBondContact O-N 2.82Å; K176-S320 WeakPolarHBondContact CA-OG 3.36Å; K176-T495 PolarHBondContact NZ-OG1 2.6Å
177E93.8Very high90.8Very high47 Ų4731.9 Ų31.922%0.2218%0.177CC..Hα-helixtrans-66.8-41.5175.6-174.957.2-145.700110.7E174 M179 A180 R181 R207E174-E177 VanDerWaalsContact OE2-CA 3.3Å; E174-E177 WeakPolarHBondContact OE2-CA 3.29Å; E174-E177 WeakPolarHBondContact OE2-CB 3.41Å; E174-E177 PolarHBondContact OE2-N 3.03Å; E177-M179 VanDerWaalsContact C-N 3.35Å; E177-M179 PolarHBondContact O-N 2.98Å; E177-A180 PolarHBondContact O-N 2.85Å; E177-R181 HydrophobicContact CG-CG 4.36Å; E177-R181 WeakPolarHBondContact O-CB 3.25Å; E177-R181 WeakPolarHBondContact O-CD 3.41Å; E177-R181 WeakPolarHBondContact O-CG 3.48Å; E177-R181 PolarHBondContact O-N 2.97Å; E177-R181 WeakPolarHBondContact OE1-CG 3.31Å; E177-R207 IonicContact OE1-CZ 2.7Å; E177-R207 IonicContact OE1-NE 3.49Å; E177-R207 PolarHBondContact OE1-NE 2.75Å; E177-R207 IonicContact OE1-NH2 3.93Å; E177-R207 IonicContact OE2-CZ 3.13Å; E177-R207 IonicContact OE2-NE 3.31Å; E177-R207 PolarHBondContact OE2-NE 3.13Å; E177-R207 IonicContact OE2-NH2 3.92Å; E177-R207 PolarHBondContact OE2-NH2 2.82Å
178L95.3Very high91.9Very high7 Ų728.6 Ų28.64%0.03715%0.15CC..Hα-helixtrans-58.7-46176.4-177.463.2000111.7F156 I160 L173 E174 I175 R181 F182F156-L178 HydrophobicContact CD2-CD1 4.37Å; F156-L178 HydrophobicContact CE2-CD1 3.61Å; F156-L178 HydrophobicContact CE2-CD2 4.21Å; F156-L178 HydrophobicContact CE2-CG 3.62Å; F156-L178 HydrophobicContact CZ-CD2 4.37Å; F156-L178 HydrophobicContact CZ-CG 4.12Å; I160-L178 HydrophobicContact CD1-CD2 4Å; I160-L178 HydrophobicContact CG1-CD1 4.27Å; I160-L178 HydrophobicContact CG1-CD2 3.92Å; L173-L178 HydrophobicContact CD1-CD2 4.03Å; E174-L178 WeakPolarHBondContact O-CB 3.41Å; E174-L178 PolarHBondContact O-N 2.95Å; I175-L178 HydrophobicContact CD1-CD2 4.44Å; I175-L178 PolarHBondContact O-N 3.44Å; L178-R181 PolarHBondContact O-N 3.48Å; L178-F182 PolarHBondContact O-N 3.14Å; L178-F182 VanDerWaalsContact O-N 3.1Å
179M96.7Very high93.2Very high0 Ų020.2 Ų20.20%011%0.112CC..Hα-helixtrans-66.4-38.2174.1-68.4-61.895.100112.5F156 I175 K176 E177 R181 F182 T183 M319 S320 L323 I468F156-M179 HydrophobicContact CE1-CE 3.85Å; F156-M179 HydrophobicContact CE2-CE 3.89Å; F156-M179 HydrophobicContact CZ-CE 3.13Å; I175-M179 HydrophobicContact CG2-CG 4Å; I175-M179 WeakPolarHBondContact O-CB 3.42Å; I175-M179 WeakPolarHBondContact O-CG 3.42Å; I175-M179 PolarHBondContact O-N 3.41Å; K176-M179 PolarHBondContact O-N 3.24Å; E177-M179 VanDerWaalsContact C-N 3.35Å; E177-M179 PolarHBondContact O-N 2.98Å; M179-R181 VanDerWaalsContact C-N 3.34Å; M179-F182 PolarHBondContact O-N 3.04Å; M179-T183 VanDerWaalsContact O-CG2 3.3Å; M179-T183 WeakPolarHBondContact O-CG2 3.44Å; M179-T183 PolarHBondContact O-N 3.15Å; M179-T183 PolarHBondContact O-OG1 2.75Å; M179-M319 HydrophobicContact CB-CE 4.4Å; M179-M319 HydrophobicContact CG-CB 3.97Å; M179-M319 HydrophobicContact SD-CB 3.39Å; M179-M319 WeakPolarHBondContact SD-CB 3.34Å; M179-M319 HydrophobicContact SD-CE 3.76Å; M179-M319 HydrophobicContact SD-CG 4.19Å; M179-M319 HydrophobicContact SD-SD 3.73Å; M179-S320 WeakPolarHBondContact CG-OG 3.48Å; M179-L323 HydrophobicContact CE-CD1 4.44Å; M179-L323 HydrophobicContact SD-CD1 4.16Å; M179-I468 HydrophobicContact CE-CD1 3.55Å; M179-I468 HydrophobicContact SD-CD1 4.31Å
180A93.9Very high93.7Very high1 Ų115 Ų151%0.0089%0.085CC..Hα-helixtrans-65.3-38.4177.600000111.8K176 E177 T183 T184 R207K176-A180 VanDerWaalsContact O-CB 3.26Å; K176-A180 WeakPolarHBondContact O-CB 3.12Å; K176-A180 PolarHBondContact O-N 2.82Å; E177-A180 PolarHBondContact O-N 2.85Å; A180-T183 PolarHBondContact O-OG1 2.79Å; A180-T183 VanDerWaalsContact O-OG1 3.13Å; A180-T184 WeakPolarHBondContact O-CB 3.39Å; A180-T184 PolarHBondContact O-N 2.76Å; A180-T184 PolarHBondContact O-OG1 3.25Å; A180-R207 VanDerWaalsContact CB-CZ 3.48Å
181R94.5Very high93.4Very high21 Ų2114.4 Ų14.48%0.0798%0.078CC..Hα-helixtrans-67.6-46.8175.7-67.4164.971.8-164.96.8111.3E177 L178 M179 T183 T184 D185 T198 L199E177-R181 HydrophobicContact CG-CG 4.36Å; E177-R181 WeakPolarHBondContact O-CB 3.25Å; E177-R181 WeakPolarHBondContact O-CD 3.41Å; E177-R181 WeakPolarHBondContact O-CG 3.48Å; E177-R181 PolarHBondContact O-N 2.97Å; E177-R181 WeakPolarHBondContact OE1-CG 3.31Å; L178-R181 PolarHBondContact O-N 3.48Å; M179-R181 VanDerWaalsContact C-N 3.34Å; R181-T183 PolarHBondContact O-N 2.88Å; R181-T184 PolarHBondContact O-N 3.37Å; R181-D185 PolarHBondContact O-N 2.88Å; R181-T198 WeakPolarHBondContact CA-OG1 3.41Å; R181-T198 PolarHBondContact NE-O 2.88Å; R181-T198 PolarHBondContact NH2-O 3.19Å; R181-T198 PolarHBondContact O-OG1 3.06Å; R181-L199 HydrophobicContact CB-CD2 3.98Å; R181-L199 PolarHBondContact NH2-O 3.42Å
182F96.3Very high92.7Very high0 Ų013.6 Ų13.60%07%0.07CC..Hα-helixtrans-55.6-51.9175.2170.6-116.3000112.1V152 F156 L178 M179 T184 D185 V186 L199 M319V152-F182 HydrophobicContact CG1-CD2 3.92Å; V152-F182 HydrophobicContact CG1-CE2 3.98Å; F156-F182 HydrophobicContact CB-CD2 3.77Å; F156-F182 HydrophobicContact CB-CE2 4.28Å; F156-F182 HydrophobicContact CD1-CD2 4.03Å; F156-F182 HydrophobicContact CD1-CE2 4.39Å; F156-F182 HydrophobicContact CD1-CG 4.23Å; F156-F182 HydrophobicContact CD2-CB 3.93Å; F156-F182 HydrophobicContact CD2-CD2 4.29Å; F156-F182 HydrophobicContact CD2-CG 4.31Å; F156-F182 HydrophobicContact CE2-CB 4.1Å; F156-F182 HydrophobicContact CG-CB 4.23Å; F156-F182 AromaticContact CG-CD2 3.76Å; F156-F182 HydrophobicContact CG-CD2 3.76Å; F156-F182 HydrophobicContact CG-CE2 4.43Å; F156-F182 HydrophobicContact CG-CG 4.1Å; L178-F182 PolarHBondContact O-N 3.14Å; L178-F182 VanDerWaalsContact O-N 3.1Å; M179-F182 PolarHBondContact O-N 3.04Å; F182-T184 VanDerWaalsContact C-N 3.34Å; F182-T184 PolarHBondContact O-N 3.3Å; F182-D185 PolarHBondContact O-N 3.43Å; F182-V186 HydrophobicContact CD2-CG2 4.1Å; F182-V186 HydrophobicContact CE1-CG2 4.31Å; F182-V186 HydrophobicContact CE2-CG2 3.64Å; F182-V186 HydrophobicContact CZ-CG2 3.76Å; F182-V186 WeakPolarHBondContact O-CG2 3.25Å; F182-V186 PolarHBondContact O-N 3.32Å; F182-L199 HydrophobicContact CB-CD2 4.19Å; F182-M319 HydrophobicContact CD1-CE 3.77Å; F182-M319 HydrophobicContact CD1-SD 4.28Å; F182-M319 HydrophobicContact CE1-CE 4.1Å; F182-M319 HydrophobicContact CE1-SD 4.21Å
183T95.6Very high92Very high0 Ų011.4 Ų11.40%06%0.061CC..Hα-helixtrans-69.4-30.8-178.255.10000113.1M179 A180 R181 V186 I187 F312 M319M179-T183 VanDerWaalsContact O-CG2 3.3Å; M179-T183 WeakPolarHBondContact O-CG2 3.44Å; M179-T183 PolarHBondContact O-N 3.15Å; M179-T183 PolarHBondContact O-OG1 2.75Å; A180-T183 PolarHBondContact O-OG1 2.79Å; A180-T183 VanDerWaalsContact O-OG1 3.13Å; R181-T183 PolarHBondContact O-N 2.88Å; T183-V186 PolarHBondContact O-N 3.37Å; T183-I187 WeakPolarHBondContact O-CG2 3.23Å; T183-I187 PolarHBondContact O-N 3.5Å; T183-F312 PolarHBondContact OG1-O 3.14Å; T183-M319 HydrophobicContact CG2-CE 3.23Å
184T94.3Very high91.3Very high0 Ų012.6 Ų12.60%07%0.067CC..Hα-helixtrans-63-45.6171.8-64.60000111.1A180 R181 F182 I187 G188 C196 T198 F206 Y308A180-T184 WeakPolarHBondContact O-CB 3.39Å; A180-T184 PolarHBondContact O-N 2.76Å; A180-T184 PolarHBondContact O-OG1 3.25Å; R181-T184 PolarHBondContact O-N 3.37Å; F182-T184 VanDerWaalsContact C-N 3.34Å; F182-T184 PolarHBondContact O-N 3.3Å; T184-I187 WeakPolarHBondContact O-CG2 3.49Å; T184-G188 PolarHBondContact O-N 2.94Å; T184-C196 HydrophobicContact CG2-CB 4.41Å; T184-T198 HydrophobicContact CG2-CG2 3.67Å; T184-F206 HydrophobicContact CG2-CB 4.49Å; T184-Y308 HydrophobicContact CG2-CE2 4.13Å
185D94.3Very high90.7Very high9 Ų916 Ų165%0.0488%0.083CC..Hα-helixtrans-68.5-36.6178.2-74.31.3000111.7V152 R181 F182 T189 C196 N197 T198 L199V152-D185 HydrophobicContact CG1-CB 3.74Å; R181-D185 PolarHBondContact O-N 2.88Å; F182-D185 PolarHBondContact O-N 3.43Å; D185-T189 VanDerWaalsContact O-CB 3.3Å; D185-T189 WeakPolarHBondContact O-CB 3.46Å; D185-T189 PolarHBondContact O-N 3.44Å; D185-T189 PolarHBondContact O-OG1 2.85Å; D185-C196 WeakPolarHBondContact OD1-CB 3.27Å; D185-N197 PolarHBondContact OD1-N 2.84Å; D185-T198 VanDerWaalsContact CG-OG1 3.28Å; D185-T198 VanDerWaalsContact OD1-CB 3.31Å; D185-T198 WeakPolarHBondContact OD1-CB 3.28Å; D185-T198 WeakPolarHBondContact OD1-CG2 3.35Å; D185-T198 PolarHBondContact OD1-N 2.75Å; D185-T198 PolarHBondContact OD1-OG1 2.94Å; D185-T198 PolarHBondContact OD2-N 2.75Å; D185-T198 VanDerWaalsContact OD2-N 3.1Å; D185-L199 HydrophobicContact CB-CD1 4.5Å; D185-L199 WeakPolarHBondContact OD2-CB 3.31Å; D185-L199 VanDerWaalsContact OD2-CG 3.31Å; D185-L199 WeakPolarHBondContact OD2-CG 3.33Å; D185-L199 PolarHBondContact OD2-N 2.9Å
186V94.4Very high90.1Very high0 Ų016.6 Ų16.60%09%0.087CC..Hα-helixtrans-61.5-54.2174.1167.60000111V149 V152 F182 T183 T189 C190 F456 Q460V149-V186 HydrophobicContact CG1-CG1 4.23Å; V149-V186 HydrophobicContact CG1-CG2 4.06Å; V149-V186 HydrophobicContact CG2-CG1 4.11Å; V152-V186 HydrophobicContact CB-CG2 4.05Å; V152-V186 HydrophobicContact CG1-CG2 3.74Å; F182-V186 HydrophobicContact CD2-CG2 4.1Å; F182-V186 HydrophobicContact CE1-CG2 4.31Å; F182-V186 HydrophobicContact CE2-CG2 3.64Å; F182-V186 HydrophobicContact CZ-CG2 3.76Å; F182-V186 WeakPolarHBondContact O-CG2 3.25Å; F182-V186 PolarHBondContact O-N 3.32Å; T183-V186 PolarHBondContact O-N 3.37Å; V186-T189 PolarHBondContact O-N 3.11Å; V186-C190 VanDerWaalsContact O-CB 3.24Å; V186-C190 WeakPolarHBondContact O-CB 3.48Å; V186-C190 PolarHBondContact O-N 2.78Å; V186-C190 PolarHBondContact O-SG 3.04Å; V186-F456 HydrophobicContact CG1-CE1 4.32Å; V186-F456 HydrophobicContact CG1-CZ 3.72Å; V186-Q460 HydrophobicContact CG1-CB 4.09Å
187I91.4Very high89.7Confident8 Ų819 Ų194%0.04110%0.102CC..Hα-helixtrans-68.2-38.5-179-165.566.4000111.5T183 T184 T189 A191 F192 Y308 F312 F456T183-I187 WeakPolarHBondContact O-CG2 3.23Å; T183-I187 PolarHBondContact O-N 3.5Å; T184-I187 WeakPolarHBondContact O-CG2 3.49Å; I187-T189 VanDerWaalsContact C-N 3.35Å; I187-T189 PolarHBondContact O-N 3.08Å; I187-A191 HydrophobicContact CD1-CB 3.69Å; I187-A191 HydrophobicContact CG1-CB 4.08Å; I187-A191 WeakPolarHBondContact O-CA 3.4Å; I187-A191 WeakPolarHBondContact O-CB 3.36Å; I187-A191 PolarHBondContact O-N 3.05Å; I187-F192 HydrophobicContact CG1-CE2 4.07Å; I187-Y308 HydrophobicContact CG2-CD2 3.8Å; I187-Y308 HydrophobicContact CG2-CE2 4.08Å; I187-F312 HydrophobicContact CG2-CB 4.35Å; I187-F456 HydrophobicContact CD1-CE1 3.75Å; I187-F456 HydrophobicContact CD1-CZ 4.06Å
188G90.2Very high89.5Confident0 Ų016.8 Ų16.80%09%0.091CC..Iπ-helixtrans-52.7-52.1173.900000112T184 F192 G193 I194T184-G188 PolarHBondContact O-N 2.94Å; G188-F192 CarbonylContact O-C 3.58Å; G188-F192 WeakPolarHBondContact O-CA 3.32Å; G188-F192 WeakPolarHBondContact O-CB 3.4Å; G188-F192 PolarHBondContact O-N 3.42Å; G188-F192 VanDerWaalsContact O-N 3.15Å; G188-G193 PolarHBondContact O-N 2.69Å; G188-I194 CarbonylContact C-O 3.56Å; G188-I194 PolarHBondContact O-N 3.31Å
189T89Confident89.3Confident18 Ų1816.6 Ų16.611%0.119%0.09CC..Iπ-helixtrans-76.9-44.1-174.8-49.30000112.3T148 D185 V186 I187 G193 I194 R268T148-T189 HydrophobicContact CG2-CG2 3.37Å; D185-T189 VanDerWaalsContact O-CB 3.3Å; D185-T189 WeakPolarHBondContact O-CB 3.46Å; D185-T189 PolarHBondContact O-N 3.44Å; D185-T189 PolarHBondContact O-OG1 2.85Å; V186-T189 PolarHBondContact O-N 3.11Å; I187-T189 VanDerWaalsContact C-N 3.35Å; I187-T189 PolarHBondContact O-N 3.08Å; T189-G193 WeakPolarHBondContact O-CA 3.25Å; T189-G193 PolarHBondContact O-N 3.04Å; T189-I194 PolarHBondContact N-O 3.46Å; T189-R268 PolarHBondContact O-NH2 3.15Å
190C86.5Confident89Confident6 Ų622.5 Ų22.54%0.04111%0.112CC..Iπ-helixtrans-76.4-43.2-176.3-70.80000113M145 T148 V186 F456M145-C190 HydrophobicContact SD-CB 3.98Å; T148-C190 VanDerWaalsContact CG2-SG 3.56Å; V186-C190 VanDerWaalsContact O-CB 3.24Å; V186-C190 WeakPolarHBondContact O-CB 3.48Å; V186-C190 PolarHBondContact O-N 2.78Å; V186-C190 PolarHBondContact O-SG 3.04Å; C190-F456 HydrophobicContact CB-CE2 4.03Å; C190-F456 HydrophobicContact CB-CZ 4.13Å
191A80.7Confident88.6Confident7 Ų726.3 Ų26.36%0.05814%0.136CC..Iπ-helixtrans-87.1-44.2-176.100000111.9I187 F271 M272I187-A191 HydrophobicContact CD1-CB 3.69Å; I187-A191 HydrophobicContact CG1-CB 4.08Å; I187-A191 WeakPolarHBondContact O-CA 3.4Å; I187-A191 WeakPolarHBondContact O-CB 3.36Å; I187-A191 PolarHBondContact O-N 3.05Å; A191-F271 HydrophobicContact CB-CB 4.01Å; A191-F271 HydrophobicContact CB-CD1 4.29Å; A191-F271 WeakPolarHBondContact O-CA 3.3Å; A191-F271 VanDerWaalsContact O-CB 3.26Å; A191-F271 WeakPolarHBondContact O-CB 3.44Å; A191-F271 PolarHBondContact O-N 3.41Å; A191-F271 VanDerWaalsContact O-N 3.09Å; A191-M272 PolarHBondContact O-N 2.89Å
192F80.3Confident87.7Confident1 Ų128.3 Ų28.30%0.00415%0.152CC..Iπ-helixtrans-105.8-12.9-169.7-48.1-53.7000113.5I187 G188 I194 R261 F271 M272 V304 Y308I187-F192 HydrophobicContact CG1-CE2 4.07Å; G188-F192 CarbonylContact O-C 3.58Å; G188-F192 WeakPolarHBondContact O-CA 3.32Å; G188-F192 WeakPolarHBondContact O-CB 3.4Å; G188-F192 PolarHBondContact O-N 3.42Å; G188-F192 VanDerWaalsContact O-N 3.15Å; F192-I194 HydrophobicContact CB-CB 4.41Å; F192-I194 HydrophobicContact CB-CD1 3.86Å; F192-I194 HydrophobicContact CB-CG1 3.96Å; F192-R261 PolarHBondContact O-NH2 3.31Å; F192-F271 HydrophobicContact CE1-CD1 4.25Å; F192-M272 HydrophobicContact CD1-CE 4.29Å; F192-V304 HydrophobicContact CD1-CG1 3.94Å; F192-V304 HydrophobicContact CD1-CG2 4.35Å; F192-V304 HydrophobicContact CE1-CB 4.03Å; F192-V304 HydrophobicContact CE1-CG1 3.58Å; F192-V304 HydrophobicContact CE1-CG2 4.04Å; F192-V304 HydrophobicContact CZ-CG1 4.08Å; F192-V304 WeakPolarHBondContact CZ-O 3.34Å; F192-Y308 AromaticContact CE2-CD2 3.92Å; F192-Y308 HydrophobicContact CE2-CD2 3.92Å; F192-Y308 HydrophobicContact CE2-CG 4.3Å
193G80.8Confident86.8Confident17 Ų1734.1 Ų34.118%0.17519%0.187CC..  trans67.828.9-174.800000112.5G188 T189 R268 D270G188-G193 PolarHBondContact O-N 2.69Å; T189-G193 WeakPolarHBondContact O-CA 3.25Å; T189-G193 PolarHBondContact O-N 3.04Å; G193-R268 VanDerWaalsContact C-NH1 3.31Å; G193-R268 PolarHBondContact O-NH1 3.46Å; G193-D270 WeakPolarHBondContact CA-OD2 3.44Å
194I82.8Confident86.1Confident39 Ų3935 Ų3520%0.219%0.193CC..  trans-113.9126.7-176.4-60.8175.7000108.6G188 T189 F192 C196 F206 L253G188-I194 CarbonylContact C-O 3.56Å; G188-I194 PolarHBondContact O-N 3.31Å; T189-I194 PolarHBondContact N-O 3.46Å; F192-I194 HydrophobicContact CB-CB 4.41Å; F192-I194 HydrophobicContact CB-CD1 3.86Å; F192-I194 HydrophobicContact CB-CG1 3.96Å; I194-C196 PolarHBondContact O-N 3.42Å; I194-F206 HydrophobicContact CD1-CZ 3.81Å; I194-F206 HydrophobicContact CG2-CE2 4Å; I194-F206 HydrophobicContact CG2-CZ 4.11Å; I194-L253 HydrophobicContact CD1-CD1 3.6Å; I194-L253 HydrophobicContact CD1-CG 4.49Å
195E83.4Confident85.6Confident116 Ų11640.4 Ų40.454%0.54222%0.222SC..  trans-81.793.6171.8-64.1-173.1172.300108.7N197E195-N197 PolarHBondContact O-N 2.85Å
196C83.2Confident85Confident16 Ų1641.1 Ų41.111%0.10823%0.225CC..  trans-70.7-23.1179.7-58.10000112.5T184 D185 I194 T198T184-C196 HydrophobicContact CG2-CB 4.41Å; D185-C196 WeakPolarHBondContact OD1-CB 3.27Å; I194-C196 PolarHBondContact O-N 3.42Å; C196-T198 HydrophobicContact CB-CG2 3.73Å; C196-T198 PolarHBondContact O-N 3.19Å
197N86.7Confident84.7Confident87 Ų8741.8 Ų41.847%0.46523%0.227SC..  trans48.731.4179.2-67.3-35.6000113.7D185 E195 L199 R200 T201D185-N197 PolarHBondContact OD1-N 2.84Å; E195-N197 PolarHBondContact O-N 2.85Å; N197-L199 PolarHBondContact O-N 2.74Å; N197-R200 PolarHBondContact O-N 3.02Å; N197-T201 PolarHBondContact O-N 3.04Å
198T89.6Confident84.6Confident0 Ų043.6 Ų43.60%024%0.239CC..THydrogen-bonded Turntrans-68.6-27.2-175.467.10000111.2R181 T184 D185 C196 R200 T201 S204R181-T198 WeakPolarHBondContact CA-OG1 3.41Å; R181-T198 PolarHBondContact NE-O 2.88Å; R181-T198 PolarHBondContact NH2-O 3.19Å; R181-T198 PolarHBondContact O-OG1 3.06Å; T184-T198 HydrophobicContact CG2-CG2 3.67Å; D185-T198 VanDerWaalsContact CG-OG1 3.28Å; D185-T198 VanDerWaalsContact OD1-CB 3.31Å; D185-T198 WeakPolarHBondContact OD1-CB 3.28Å; D185-T198 WeakPolarHBondContact OD1-CG2 3.35Å; D185-T198 PolarHBondContact OD1-N 2.75Å; D185-T198 PolarHBondContact OD1-OG1 2.94Å; D185-T198 PolarHBondContact OD2-N 2.75Å; D185-T198 VanDerWaalsContact OD2-N 3.1Å; C196-T198 HydrophobicContact CB-CG2 3.73Å; C196-T198 PolarHBondContact O-N 3.19Å; T198-R200 VanDerWaalsContact C-N 3.25Å; T198-R200 PolarHBondContact O-N 3.45Å; T198-T201 WeakPolarHBondContact CA-O 3.37Å; T198-T201 CarbonylContact O-C 3.49Å; T198-T201 VanDerWaalsContact O-C 3.32Å; T198-T201 PolarHBondContact O-N 3.29Å; T198-S204 WeakPolarHBondContact CG2-OG 3.41Å
199L90.3Very high84.6Confident3 Ų344.8 Ų44.82%0.01625%0.245CC..THydrogen-bonded Turntrans-60.8-26.1173.9-75.4173.8000114.8V152 F156 V159 R181 F182 D185 N197V152-L199 HydrophobicContact CG1-CD1 4.09Å; F156-L199 HydrophobicContact CB-CD1 3.92Å; F156-L199 HydrophobicContact CD2-CD1 4.49Å; F156-L199 HydrophobicContact CD2-CD2 3.62Å; F156-L199 HydrophobicContact CE2-CD2 4.35Å; V159-L199 WeakPolarHBondContact CG1-O 3.25Å; V159-L199 HydrophobicContact CG2-CB 4.35Å; R181-L199 HydrophobicContact CB-CD2 3.98Å; R181-L199 PolarHBondContact NH2-O 3.42Å; F182-L199 HydrophobicContact CB-CD2 4.19Å; D185-L199 HydrophobicContact CB-CD1 4.5Å; D185-L199 WeakPolarHBondContact OD2-CB 3.31Å; D185-L199 VanDerWaalsContact OD2-CG 3.31Å; D185-L199 WeakPolarHBondContact OD2-CG 3.33Å; D185-L199 PolarHBondContact OD2-N 2.9Å; N197-L199 PolarHBondContact O-N 2.74Å
200R89.9Confident84.4Confident123 Ų12344 Ų4446%0.46424%0.239SC..THydrogen-bonded Turntrans-105.2-30.1173.1-70.1-162.8174.8-83.7-6.1113.2E155 V159 E162 N197 T198 P202E155-R200 IonicContact OE1-CZ 3.07Å; E155-R200 IonicContact OE1-NE 2.67Å; E155-R200 PolarHBondContact OE1-NE 2.92Å; E155-R200 IonicContact OE1-NH2 2.95Å; E155-R200 PolarHBondContact OE1-NH2 2.91Å; V159-R200 HydrophobicContact CG2-CG 4.16Å; E162-R200 IonicContact OE1-CZ 3.64Å; E162-R200 IonicContact OE1-NH1 3.36Å; E162-R200 PolarHBondContact OE1-NH1 3.32Å; E162-R200 IonicContact OE1-NH2 3.79Å; E162-R200 PolarHBondContact OE1-NH2 3.14Å; E162-R200 IonicContact OE2-CZ 3.78Å; E162-R200 IonicContact OE2-NH1 2.89Å; E162-R200 PolarHBondContact OE2-NH1 3.44Å; E162-R200 IonicContact OE2-NH2 3.44Å; N197-R200 PolarHBondContact O-N 3.02Å; T198-R200 VanDerWaalsContact C-N 3.25Å; T198-R200 PolarHBondContact O-N 3.45Å; R200-P202 WeakPolarHBondContact O-CD 3.42Å
201T86.4Confident84.4Confident81 Ų8147.1 Ų47.150%0.49725%0.253SS..  trans-11788.6180-50.30000109.4N197 T198 V203N197-T201 PolarHBondContact O-N 3.04Å; T198-T201 WeakPolarHBondContact CA-O 3.37Å; T198-T201 CarbonylContact O-C 3.49Å; T198-T201 VanDerWaalsContact O-C 3.32Å; T198-T201 PolarHBondContact O-N 3.29Å; T201-V203 PolarHBondContact O-N 3.33Å
202P75.1Confident84.8Confident64 Ų6449.3 Ų49.342%0.41626%0.262SS..SBendtrans-59.1-32.6-173-1318.4000113.5R200 S204R200-P202 WeakPolarHBondContact O-CD 3.42Å; P202-S204 PolarHBondContact O-N 2.72Å
203V78.1Confident85.1Confident122 Ų12250.7 Ų50.774%0.73927%0.27SS*.  trans-92.399.2177.8-174.10000108.7T201T201-V203 PolarHBondContact O-N 3.33Å
204S81.8Confident85.1Confident19 Ų1952.2 Ų52.213%0.13327%0.272CS..  trans-127.1153.4171.875.30000110.9T198 P202 F206 R207 T208T198-S204 WeakPolarHBondContact CG2-OG 3.41Å; P202-S204 PolarHBondContact O-N 2.72Å; S204-F206 PolarHBondContact O-N 3Å; S204-R207 PolarHBondContact O-N 2.76Å; S204-R207 WeakPolarHBondContact OG-CB 3.5Å; S204-R207 PolarHBondContact OG-N 3.48Å; S204-R207 VanDerWaalsContact OG-N 3.09Å; S204-T208 WeakPolarHBondContact O-CB 3.37Å; S204-T208 PolarHBondContact O-N 3.46Å; S204-T208 PolarHBondContact O-OG1 2.87Å
205D83.4Confident85.1Confident113 Ų11355 Ų5560%0.60429%0.291SS*.Hα-helixtrans-59.1-39.9175.3-71.9-15.1000110.9T208 M209 F249D205-T208 PolarHBondContact O-N 3.03Å; D205-M209 VanDerWaalsContact O-CB 3.3Å; D205-M209 WeakPolarHBondContact O-CB 3.21Å; D205-M209 WeakPolarHBondContact O-CG 3.23Å; D205-M209 PolarHBondContact O-N 3.49Å; D205-F249 HydrophobicContact CB-CD2 4.4Å; D205-F249 HydrophobicContact CB-CE2 3.73Å; D205-F249 HydrophobicContact CB-CZ 4.39Å
206F82.1Confident85.2Confident23 Ų2352.9 Ų52.910%0.10128%0.283CS..Hα-helixtrans-56-55.9175.1-86.9-87.4000111.5T184 I194 S204 T208 M209 G210 F249 L253 Y308T184-F206 HydrophobicContact CG2-CB 4.49Å; I194-F206 HydrophobicContact CD1-CZ 3.81Å; I194-F206 HydrophobicContact CG2-CE2 4Å; I194-F206 HydrophobicContact CG2-CZ 4.11Å; S204-F206 PolarHBondContact O-N 3Å; F206-T208 VanDerWaalsContact C-N 3.34Å; F206-T208 PolarHBondContact O-N 3.43Å; F206-M209 PolarHBondContact O-N 2.89Å; F206-G210 PolarHBondContact O-N 3.14Å; F206-F249 HydrophobicContact CD1-CE1 4.2Å; F206-F249 HydrophobicContact CD1-CZ 4.04Å; F206-F249 AromaticContact CD2-CZ 3.93Å; F206-F249 HydrophobicContact CD2-CZ 3.93Å; F206-F249 HydrophobicContact CE1-CE1 4.3Å; F206-F249 HydrophobicContact CE1-CZ 4.14Å; F206-F249 HydrophobicContact CE2-CZ 4.02Å; F206-F249 HydrophobicContact CG-CE1 4.49Å; F206-F249 AromaticContact CG-CZ 3.94Å; F206-F249 HydrophobicContact CG-CZ 3.94Å; F206-F249 HydrophobicContact CZ-CZ 4.13Å; F206-L253 HydrophobicContact CE1-CD1 4.49Å; F206-L253 HydrophobicContact CE1-CD2 3.57Å; F206-L253 HydrophobicContact CE2-CD1 4.3Å; F206-L253 HydrophobicContact CZ-CD1 3.62Å; F206-L253 HydrophobicContact CZ-CD2 3.55Å; F206-L253 HydrophobicContact CZ-CG 4.24Å; F206-Y308 HydrophobicContact CD1-CD2 4.32Å; F206-Y308 AromaticContact CD1-CE2 3.82Å; F206-Y308 HydrophobicContact CD1-CE2 3.82Å; F206-Y308 PolarHBondContact O-OH 2.77Å
207R86.8Confident85.3Confident14 Ų1456 Ų565%0.05330%0.298CS..Hα-helixtrans-60.2-45.7-177.8-179.465.8-175.9121.1-0.1111.3E177 A180 S204 G210 Q211E177-R207 IonicContact OE1-CZ 2.7Å; E177-R207 IonicContact OE1-NE 3.49Å; E177-R207 PolarHBondContact OE1-NE 2.75Å; E177-R207 IonicContact OE1-NH2 3.93Å; E177-R207 IonicContact OE2-CZ 3.13Å; E177-R207 IonicContact OE2-NE 3.31Å; E177-R207 PolarHBondContact OE2-NE 3.13Å; E177-R207 IonicContact OE2-NH2 3.92Å; E177-R207 PolarHBondContact OE2-NH2 2.82Å; A180-R207 VanDerWaalsContact CB-CZ 3.48Å; S204-R207 PolarHBondContact O-N 2.76Å; S204-R207 WeakPolarHBondContact OG-CB 3.5Å; S204-R207 PolarHBondContact OG-N 3.48Å; S204-R207 VanDerWaalsContact OG-N 3.09Å; R207-G210 PolarHBondContact O-N 3.45Å; R207-Q211 WeakPolarHBondContact O-CG 3.39Å; R207-Q211 PolarHBondContact O-N 3.05Å
208T89.1Confident85.3Confident46 Ų4655.7 Ų55.728%0.28229%0.29SS..Hα-helixtrans-62.9-48.8-179-53.90000111.3S204 D205 F206 G210 Q211 K212S204-T208 WeakPolarHBondContact O-CB 3.37Å; S204-T208 PolarHBondContact O-N 3.46Å; S204-T208 PolarHBondContact O-OG1 2.87Å; D205-T208 PolarHBondContact O-N 3.03Å; F206-T208 VanDerWaalsContact C-N 3.34Å; F206-T208 PolarHBondContact O-N 3.43Å; T208-G210 VanDerWaalsContact C-N 3.33Å; T208-G210 PolarHBondContact O-N 3.18Å; T208-Q211 PolarHBondContact O-N 3.09Å; T208-K212 WeakPolarHBondContact O-CG 3.42Å; T208-K212 PolarHBondContact O-N 3.03Å; T208-K212 VanDerWaalsContact O-N 3.16Å
209M90.2Very high85.2Confident26 Ų2658.8 Ų58.813%0.12830%0.304CS..Hα-helixtrans-67.3-35179.4-64.3-58.7132.600111.8D205 F206 K212 D245 V246 F249 F250D205-M209 VanDerWaalsContact O-CB 3.3Å; D205-M209 WeakPolarHBondContact O-CB 3.21Å; D205-M209 WeakPolarHBondContact O-CG 3.23Å; D205-M209 PolarHBondContact O-N 3.49Å; F206-M209 PolarHBondContact O-N 2.89Å; M209-K212 PolarHBondContact O-N 2.74Å; M209-K212 HydrophobicContact SD-CD 4.48Å; M209-D245 HydrophobicContact SD-CB 4.42Å; M209-V246 HydrophobicContact SD-CG2 4.3Å; M209-F249 HydrophobicContact CB-CD1 3.84Å; M209-F249 HydrophobicContact CB-CE1 4.19Å; M209-F249 HydrophobicContact CB-CG 4.17Å; M209-F249 HydrophobicContact CG-CB 3.93Å; M209-F249 HydrophobicContact CG-CD1 3.85Å; M209-F249 HydrophobicContact CG-CD2 3.98Å; M209-F249 HydrophobicContact CG-CE1 4.36Å; M209-F249 HydrophobicContact CG-CE2 4.48Å; M209-F249 HydrophobicContact CG-CG 3.64Å; M209-F249 HydrophobicContact SD-CB 4.32Å; M209-F250 HydrophobicContact CB-CE2 4.49Å
210G85.9Confident85Confident0 Ų060.2 Ų60.20%032%0.32CS..Hα-helixtrans-61.3-45.6172.800000113.3F206 R207 T208 V213 F312F206-G210 PolarHBondContact O-N 3.14Å; R207-G210 PolarHBondContact O-N 3.45Å; T208-G210 VanDerWaalsContact C-N 3.33Å; T208-G210 PolarHBondContact O-N 3.18Å; G210-V213 WeakPolarHBondContact O-CB 3.45Å; G210-V213 PolarHBondContact O-N 2.91Å; G210-F312 WeakPolarHBondContact O-CZ 3.5Å
211Q86.1Confident84.5Confident72 Ų7259.9 Ų59.934%0.33632%0.322SS..Hα-helixtrans-61.5-44.3177.5-73.5175.2-18.200112R207 T208 V213 F214 T215R207-Q211 WeakPolarHBondContact O-CG 3.39Å; R207-Q211 PolarHBondContact O-N 3.05Å; T208-Q211 PolarHBondContact O-N 3.09Å; Q211-V213 PolarHBondContact O-N 3.28Å; Q211-V213 VanDerWaalsContact O-N 3.11Å; Q211-F214 PolarHBondContact O-N 2.88Å; Q211-T215 PolarHBondContact O-N 3.42Å; Q211-T215 PolarHBondContact O-OG1 3.43Å
212K89Confident84.4Confident54 Ų5462.8 Ų62.824%0.23533%0.333CS..Hα-helixtrans-58-27.8-178-74.4-171.3179.5-161.20114T208 M209 F214 T215 D216 D245 V246T208-K212 WeakPolarHBondContact O-CG 3.42Å; T208-K212 PolarHBondContact O-N 3.03Å; T208-K212 VanDerWaalsContact O-N 3.16Å; M209-K212 PolarHBondContact O-N 2.74Å; M209-K212 HydrophobicContact SD-CD 4.48Å; K212-F214 PolarHBondContact O-N 3.05Å; K212-T215 WeakPolarHBondContact CA-OG1 3.43Å; K212-T215 PolarHBondContact O-N 3.25Å; K212-D216 HydrophobicContact CB-CB 4.46Å; K212-D216 WeakPolarHBondContact O-CB 3.3Å; K212-D216 PolarHBondContact O-N 3.07Å; K212-D245 WeakPolarHBondContact CD-OD2 3.22Å; K212-D245 IonicContact NZ-OD2 3.78Å; K212-D245 PolarHBondContact NZ-OD2 3.13Å; K212-V246 HydrophobicContact CB-CG2 3.82Å
213V86.1Confident84.9Confident30 Ų3063.7 Ų63.718%0.18233%0.334CS..Hα-helixtrans-58.9-31.5175.8178.80000112.2G210 Q211 V246 F305 V309G210-V213 WeakPolarHBondContact O-CB 3.45Å; G210-V213 PolarHBondContact O-N 2.91Å; Q211-V213 PolarHBondContact O-N 3.28Å; Q211-V213 VanDerWaalsContact O-N 3.11Å; V213-V246 HydrophobicContact CG2-CG1 3.88Å; V213-F305 HydrophobicContact CG1-CE2 4.34Å; V213-F305 HydrophobicContact CG1-CZ 3.86Å; V213-F305 HydrophobicContact CG2-CE2 3.56Å; V213-F305 HydrophobicContact CG2-CZ 3.92Å; V213-V309 HydrophobicContact CB-CG2 4.38Å; V213-V309 HydrophobicContact CG1-CG1 4Å; V213-V309 HydrophobicContact CG1-CG2 4.15Å; V213-V309 HydrophobicContact CG2-CG2 3.98Å
214F82.3Confident85.2Confident48 Ų4859.1 Ų59.121%0.21131%0.307CS..Hα-helixtrans-99.8-22.5-176.5-62.7-78.6000113.5Q211 K212 V309 F312 E313 V492Q211-F214 PolarHBondContact O-N 2.88Å; K212-F214 PolarHBondContact O-N 3.05Å; F214-V309 HydrophobicContact CE1-CG1 4.2Å; F214-V309 HydrophobicContact CE2-CG1 3.59Å; F214-V309 HydrophobicContact CZ-CG1 3.28Å; F214-F312 HydrophobicContact CD2-CZ 4.33Å; F214-F312 HydrophobicContact CE2-CE1 4.39Å; F214-F312 HydrophobicContact CE2-CE2 4.47Å; F214-F312 AromaticContact CE2-CZ 3.78Å; F214-F312 HydrophobicContact CE2-CZ 3.78Å; F214-E313 HydrophobicContact CD2-CB 4.45Å; F214-E313 HydrophobicContact CD2-CG 4.15Å; F214-E313 HydrophobicContact CE1-CG 4.21Å; F214-E313 HydrophobicContact CE2-CB 3.56Å; F214-E313 HydrophobicContact CE2-CG 3.66Å; F214-E313 HydrophobicContact CZ-CB 3.6Å; F214-E313 HydrophobicContact CZ-CG 3.68Å; F214-V492 HydrophobicContact CD1-CG2 4.33Å; F214-V492 HydrophobicContact CE1-CG1 4.47Å; F214-V492 HydrophobicContact CE1-CG2 4.26Å
215T81.6Confident85.2Confident99 Ų9961 Ų6161%0.60732%0.315SS*.Hα-helixtrans-100.4-33.9-176.259.30000113.4Q211 K212Q211-T215 PolarHBondContact O-N 3.42Å; Q211-T215 PolarHBondContact O-OG1 3.43Å; K212-T215 WeakPolarHBondContact CA-OG1 3.43Å; K212-T215 PolarHBondContact O-N 3.25Å
216D85.4Confident85.4Confident70 Ų7058.3 Ų58.337%0.37430%0.298SS..  trans-102.9132.8-166.5-65.313.1000110.9K212 P243K212-D216 HydrophobicContact CB-CB 4.46Å; K212-D216 WeakPolarHBondContact O-CB 3.3Å; K212-D216 PolarHBondContact O-N 3.07Å; D216-P243 HydrophobicContact CB-CG 4.17Å
217M85.2Confident85.6Confident83 Ų8357.4 Ų57.441%0.40929%0.294SS..  trans-110.1113.4174.2-65-176-176.300109.5H219 G220 K221 T224M217-H219 PolarHBondContact O-N 2.74Å; M217-G220 PolarHBondContact O-N 3.35Å; M217-K221 HydrophobicContact SD-CG 3.94Å; M217-T224 HydrophobicContact SD-CG2 4.32Å
218R87.8Confident85.4Confident79 Ų7959.8 Ų59.830%0.29831%0.305SS..THydrogen-bonded Turntrans-46.7-42.6-176.5-170.9-164.9179.584.94.5113.6R240 M241 M242 E244R218-R240 VanDerWaalsContact CD-O 3.25Å; R218-R240 WeakPolarHBondContact CD-O 3.44Å; R218-M241 WeakPolarHBondContact CB-O 3.28Å; R218-M242 VanDerWaalsContact CD-O 3.25Å; R218-M242 WeakPolarHBondContact CD-O 3.32Å; R218-M242 PolarHBondContact NH1-O 3.46Å; R218-E244 IonicContact CZ-OE2 3.06Å; R218-E244 VanDerWaalsContact CZ-OE2 3.24Å; R218-E244 IonicContact NH1-OE2 3.45Å; R218-E244 PolarHBondContact NH1-OE2 3.29Å; R218-E244 IonicContact NH2-OE2 2.78Å; R218-E244 PolarHBondContact NH2-OE2 3.05Å
219H86.4Confident85.1Confident66 Ų6657.9 Ų57.931%0.30629%0.294SS..THydrogen-bonded Turntrans-1129.7-174.1-60.7-52.5000113.6M217 L223 R240M217-H219 PolarHBondContact O-N 2.74Å; H219-L223 HydrophobicContact CB-CB 3.42Å; H219-L223 VanDerWaalsContact CB-CB 3.42Å; H219-L223 HydrophobicContact CB-CD1 3.81Å; H219-L223 HydrophobicContact CB-CG 4.26Å; H219-R240 PolarHBondContact CD2-O 3.49Å; H219-R240 PolarHBondContact NE2-O 2.95Å
220G85.7Confident84.9Confident33 Ų3360.8 Ų60.834%0.3431%0.306SS..Hα-helixtrans67.1175.7-170.500000113.8M217 L222 T224M217-G220 PolarHBondContact O-N 3.35Å; G220-L222 PolarHBondContact O-N 3.29Å; G220-T224 WeakPolarHBondContact O-CB 3.37Å; G220-T224 PolarHBondContact O-N 2.99Å; G220-T224 VanDerWaalsContact O-N 3.1Å; G220-T224 PolarHBondContact O-OG1 2.89Å
221K81.2Confident85Confident116 Ų11662.1 Ų62.150%0.50431%0.314SS..Hα-helixtrans-58-46.1-168-64.6-177.6179.7-177.40114.2M217 T224 I225 M489M217-K221 HydrophobicContact SD-CG 3.94Å; K221-T224 PolarHBondContact O-N 3.32Å; K221-I225 WeakPolarHBondContact O-CB 3.43Å; K221-I225 VanDerWaalsContact O-CG1 3.26Å; K221-I225 WeakPolarHBondContact O-CG1 3.18Å; K221-I225 PolarHBondContact O-N 2.97Å; K221-M489 WeakPolarHBondContact CE-SD 3.33Å; K221-M489 PolarHBondContact NZ-SD 3.36Å
222L82.3Confident85Confident141 Ų14166.1 Ų66.174%0.73833%0.33SS*.Hα-helixtrans-65.8-45.9-172.9-67.8177000112.6G220 I225 F226G220-L222 PolarHBondContact O-N 3.29Å; L222-I225 WeakPolarHBondContact O-CB 3.43Å; L222-I225 PolarHBondContact O-N 2.95Å; L222-F226 PolarHBondContact O-N 2.9Å
223L86.1Confident85Confident83 Ų8367.2 Ų67.244%0.43534%0.338SS..Hα-helixtrans-74.2-31.5179.2-72.3175000111.6H219 F226 V227 M239H219-L223 HydrophobicContact CB-CB 3.42Å; H219-L223 VanDerWaalsContact CB-CB 3.42Å; H219-L223 HydrophobicContact CB-CD1 3.81Å; H219-L223 HydrophobicContact CB-CG 4.26Å; L223-F226 WeakPolarHBondContact O-CB 3.48Å; L223-F226 PolarHBondContact O-N 3.26Å; L223-V227 WeakPolarHBondContact O-CG2 3.42Å; L223-V227 PolarHBondContact O-N 3.03Å; L223-M239 HydrophobicContact CB-CE 4.3Å; L223-M239 HydrophobicContact CD2-CE 4.31Å
224T84.7Confident85.3Confident27 Ų2765.8 Ų65.817%0.16633%0.33CS..Hα-helixtrans-60.4-46.2169.6-63.70000111.4M217 G220 K221 F226 V227 F228M217-T224 HydrophobicContact SD-CG2 4.32Å; G220-T224 WeakPolarHBondContact O-CB 3.37Å; G220-T224 PolarHBondContact O-N 2.99Å; G220-T224 VanDerWaalsContact O-N 3.1Å; G220-T224 PolarHBondContact O-OG1 2.89Å; K221-T224 PolarHBondContact O-N 3.32Å; T224-F226 VanDerWaalsContact C-N 3.25Å; T224-F226 PolarHBondContact O-N 3.32Å; T224-V227 PolarHBondContact O-N 2.68Å; T224-V227 VanDerWaalsContact O-N 3.13Å; T224-F228 HydrophobicContact CG2-CD2 3.77Å; T224-F228 HydrophobicContact CG2-CE2 3.49Å; T224-F228 VanDerWaalsContact CG2-CE2 3.49Å; T224-F228 VanDerWaalsContact O-CD2 3.22Å; T224-F228 WeakPolarHBondContact O-CD2 3.18Å; T224-F228 PolarHBondContact O-N 3.45Å; T224-F228 VanDerWaalsContact O-N 3.1Å
225I82.8Confident85.6Confident59 Ų5965.4 Ų65.430%0.30333%0.333SS..Hα-helixtrans-56.9-41173.3-73.6169.2000110.8L76 K221 L222 S229L76-I225 HydrophobicContact CD1-CG2 3.73Å; L76-I225 HydrophobicContact CD2-CG2 4.17Å; K221-I225 WeakPolarHBondContact O-CB 3.43Å; K221-I225 VanDerWaalsContact O-CG1 3.26Å; K221-I225 WeakPolarHBondContact O-CG1 3.18Å; K221-I225 PolarHBondContact O-N 2.97Å; L222-I225 WeakPolarHBondContact O-CB 3.43Å; L222-I225 PolarHBondContact O-N 2.95Å; I225-S229 WeakPolarHBondContact O-CB 3.11Å; I225-S229 PolarHBondContact O-N 2.98Å; I225-S229 PolarHBondContact O-OG 3.45Å
226F86.3Confident86Confident56 Ų5670.2 Ų70.225%0.24634%0.34CS..Hα-helixtrans-62.5-43.3175.6174.9-95.4000112.6L222 L223 T224 S229 F230 L233 A234 L237 M239L222-F226 PolarHBondContact O-N 2.9Å; L223-F226 WeakPolarHBondContact O-CB 3.48Å; L223-F226 PolarHBondContact O-N 3.26Å; T224-F226 VanDerWaalsContact C-N 3.25Å; T224-F226 PolarHBondContact O-N 3.32Å; F226-S229 PolarHBondContact O-N 3.07Å; F226-F230 AromaticContact CD2-CD2 3.7Å; F226-F230 HydrophobicContact CD2-CD2 3.7Å; F226-F230 HydrophobicContact CD2-CE2 4.32Å; F226-F230 HydrophobicContact CE2-CB 4.39Å; F226-F230 AromaticContact CE2-CD2 3.78Å; F226-F230 HydrophobicContact CE2-CD2 3.78Å; F226-F230 HydrophobicContact CE2-CG 4.38Å; F226-F230 PolarHBondContact O-N 3.25Å; F226-L233 HydrophobicContact CE2-CD2 4.23Å; F226-L233 HydrophobicContact CZ-CD2 3.82Å; F226-L233 HydrophobicContact CZ-CG 4.12Å; F226-A234 HydrophobicContact CE1-CB 4.26Å; F226-L237 HydrophobicContact CE1-CD1 3.99Å; F226-L237 HydrophobicContact CZ-CD1 3.96Å; F226-M239 HydrophobicContact CD1-CE 4.3Å; F226-M239 HydrophobicContact CD1-SD 3.68Å; F226-M239 HydrophobicContact CE1-SD 3.63Å
227V87.8Confident86.4Confident3 Ų371.9 Ų71.92%0.01835%0.348CS..Hα-helixtrans-60.8-47.7178173.10000111.3F106 L223 T224 S229 F230 P231 A234 M239F106-V227 HydrophobicContact CB-CG1 4.12Å; F106-V227 HydrophobicContact CD1-CG1 3.72Å; F106-V227 HydrophobicContact CD2-CG1 3.67Å; F106-V227 HydrophobicContact CE1-CG1 4Å; F106-V227 HydrophobicContact CE2-CG1 3.94Å; F106-V227 HydrophobicContact CG-CG1 3.54Å; F106-V227 HydrophobicContact CZ-CG1 4.09Å; L223-V227 WeakPolarHBondContact O-CG2 3.42Å; L223-V227 PolarHBondContact O-N 3.03Å; T224-V227 PolarHBondContact O-N 2.68Å; T224-V227 VanDerWaalsContact O-N 3.13Å; V227-S229 VanDerWaalsContact C-N 3.34Å; V227-S229 PolarHBondContact O-N 2.84Å; V227-F230 CarbonylContact O-C 3.5Å; V227-F230 PolarHBondContact O-N 2.9Å; V227-P231 VanDerWaalsContact O-CA 3.26Å; V227-P231 WeakPolarHBondContact O-CA 3.4Å; V227-A234 HydrophobicContact CB-CB 4.32Å; V227-A234 HydrophobicContact CG1-CB 4.3Å; V227-A234 HydrophobicContact CG2-CB 4.07Å; V227-M239 HydrophobicContact CG2-CB 4.38Å; V227-M239 HydrophobicContact CG2-CE 3.73Å; V227-M239 HydrophobicContact CG2-SD 4Å
228F82Confident86.7Confident64 Ų6474.7 Ų74.728%0.28135%0.354SS..Hα-helixtrans-67.3-35.6176.5-73.4-65.4000112.8K78 T224 M241K78-F228 PolarHBondContact NZ-O 3.19Å; T224-F228 HydrophobicContact CG2-CD2 3.77Å; T224-F228 HydrophobicContact CG2-CE2 3.49Å; T224-F228 VanDerWaalsContact CG2-CE2 3.49Å; T224-F228 VanDerWaalsContact O-CD2 3.22Å; T224-F228 WeakPolarHBondContact O-CD2 3.18Å; T224-F228 PolarHBondContact O-N 3.45Å; T224-F228 VanDerWaalsContact O-N 3.1Å; F228-M241 HydrophobicContact CE1-SD 4.39Å; F228-M241 HydrophobicContact CZ-SD 4.03Å
229S82.8Confident87Confident7 Ų772.1 Ų72.15%0.04935%0.346CS..Hα-helixtrans-68.5-40177.3-75.80000112.3L76 H77 K78 I225 F226 V227L76-S229 WeakPolarHBondContact CD1-OG 3.47Å; H77-S229 WeakPolarHBondContact CE1-CB 3.12Å; H77-S229 PolarHBondContact CE1-O 2.76Å; H77-S229 VanDerWaalsContact CE1-O 3.32Å; K78-S229 WeakPolarHBondContact CE-O 3.39Å; K78-S229 PolarHBondContact NZ-O 3.32Å; I225-S229 WeakPolarHBondContact O-CB 3.11Å; I225-S229 PolarHBondContact O-N 2.98Å; I225-S229 PolarHBondContact O-OG 3.45Å; F226-S229 PolarHBondContact O-N 3.07Å; V227-S229 VanDerWaalsContact C-N 3.34Å; V227-S229 PolarHBondContact O-N 2.84Å
230F85.7Confident87.2Confident87 Ų8770.8 Ų70.838%0.38234%0.338SS..  trans-134.661.7-173.1-56.5-78.9000111.3H77 F226 V227 K232 L233 A234H77-F230 AromaticContact CD2-CZ 3.99Å; H77-F230 AromaticContact CE1-CE1 3.67Å; H77-F230 AromaticContact CE1-CE2 3.81Å; H77-F230 AromaticContact CE1-CZ 3.42Å; H77-F230 VanDerWaalsContact CE1-CZ 3.42Å; H77-F230 WeakPolarHBondContact CE1-CZ 3.48Å; H77-F230 AromaticContact ND1-CZ 3.97Å; H77-F230 AromaticContact NE2-CE1 3.31Å; H77-F230 VanDerWaalsContact NE2-CE1 3.31Å; H77-F230 WeakPolarHBondContact NE2-CE1 3.39Å; H77-F230 AromaticContact NE2-CZ 3.42Å; H77-F230 WeakPolarHBondContact NE2-CZ 3.42Å; F226-F230 AromaticContact CD2-CD2 3.7Å; F226-F230 HydrophobicContact CD2-CD2 3.7Å; F226-F230 HydrophobicContact CD2-CE2 4.32Å; F226-F230 HydrophobicContact CE2-CB 4.39Å; F226-F230 AromaticContact CE2-CD2 3.78Å; F226-F230 HydrophobicContact CE2-CD2 3.78Å; F226-F230 HydrophobicContact CE2-CG 4.38Å; F226-F230 PolarHBondContact O-N 3.25Å; V227-F230 CarbonylContact O-C 3.5Å; V227-F230 PolarHBondContact O-N 2.9Å; F230-K232 VanDerWaalsContact C-N 3.3Å; F230-K232 PolarHBondContact O-N 3.3Å; F230-L233 HydrophobicContact CB-CB 3.92Å; F230-L233 HydrophobicContact CB-CD2 4.45Å; F230-L233 PolarHBondContact O-N 2.79Å; F230-A234 WeakPolarHBondContact O-CB 3.07Å; F230-A234 PolarHBondContact O-N 3.37Å
231P87.5Confident87.4Confident27 Ų2771.3 Ų71.318%0.17533%0.332CS..Hα-helixtrans-60.4-38.8-168.922.4-33.8000112.8K78 F106 V227 L233 S235K78-P231 VanDerWaalsContact NZ-CD 3.34Å; F106-P231 HydrophobicContact CB-CB 4.02Å; F106-P231 HydrophobicContact CD2-CB 3.86Å; F106-P231 HydrophobicContact CG-CB 4.44Å; V227-P231 VanDerWaalsContact O-CA 3.26Å; V227-P231 WeakPolarHBondContact O-CA 3.4Å; P231-L233 PolarHBondContact O-N 3.46Å; P231-S235 WeakPolarHBondContact O-CB 3.14Å; P231-S235 PolarHBondContact O-N 3.37Å
232K87.3Confident87.9Confident156 Ų15666.6 Ų66.668%0.67831%0.312SS*.Hα-helixtrans-64.8-38.8175.5-66.5-173.9178.3-176.30112.6F230 R236F230-K232 VanDerWaalsContact C-N 3.3Å; F230-K232 PolarHBondContact O-N 3.3Å; K232-R236 VanDerWaalsContact O-CG 3.32Å; K232-R236 WeakPolarHBondContact O-CG 3.28Å; K232-R236 PolarHBondContact O-N 2.66Å
233L89.1Confident88.4Confident77 Ų7760.4 Ų60.440%0.40328%0.28SS..Hα-helixtrans-73.9-44.6178.5-178.659000110.5F226 F230 P231 S235 R236 L237F226-L233 HydrophobicContact CE2-CD2 4.23Å; F226-L233 HydrophobicContact CZ-CD2 3.82Å; F226-L233 HydrophobicContact CZ-CG 4.12Å; F230-L233 HydrophobicContact CB-CB 3.92Å; F230-L233 HydrophobicContact CB-CD2 4.45Å; F230-L233 PolarHBondContact O-N 2.79Å; P231-L233 PolarHBondContact O-N 3.46Å; L233-S235 VanDerWaalsContact C-N 3.3Å; L233-S235 PolarHBondContact O-N 2.93Å; L233-R236 WeakPolarHBondContact O-CB 3.39Å; L233-R236 PolarHBondContact O-N 3.39Å; L233-R236 VanDerWaalsContact O-N 3.08Å; L233-L237 HydrophobicContact CD1-CD1 4.4Å; L233-L237 HydrophobicContact CD1-CG 4.36Å; L233-L237 HydrophobicContact CG-CD1 4.1Å; L233-L237 HydrophobicContact CG-CG 4.47Å; L233-L237 WeakPolarHBondContact O-CG 3.35Å; L233-L237 PolarHBondContact O-N 2.89Å
234A91.2Very high88.7Confident0 Ų059.6 Ų59.60%028%0.275CS..Hα-helixtrans-56.9-42.7175.700000112F106 F226 V227 F230 L237 R238 M239F106-A234 HydrophobicContact CD2-CB 4.43Å; F106-A234 HydrophobicContact CE2-CB 3.92Å; F226-A234 HydrophobicContact CE1-CB 4.26Å; V227-A234 HydrophobicContact CB-CB 4.32Å; V227-A234 HydrophobicContact CG1-CB 4.3Å; V227-A234 HydrophobicContact CG2-CB 4.07Å; F230-A234 WeakPolarHBondContact O-CB 3.07Å; F230-A234 PolarHBondContact O-N 3.37Å; A234-L237 CarbonylContact O-C 3.51Å; A234-L237 PolarHBondContact O-N 3.24Å; A234-R238 PolarHBondContact O-N 3.26Å; A234-M239 HydrophobicContact CB-CB 4.32Å; A234-M239 HydrophobicContact CB-CG 4.49Å; A234-M239 HydrophobicContact CB-SD 4.01Å; A234-M239 WeakPolarHBondContact O-CB 3.38Å; A234-M239 PolarHBondContact O-N 2.68Å
235S88.6Confident89.2Confident40 Ų4061.1 Ų61.128%0.2828%0.281SS..Hα-helixtrans-64.6-40.7174.4172.60000112P231 L233 L237 R238P231-S235 WeakPolarHBondContact O-CB 3.14Å; P231-S235 PolarHBondContact O-N 3.37Å; L233-S235 VanDerWaalsContact C-N 3.3Å; L233-S235 PolarHBondContact O-N 2.93Å; S235-L237 VanDerWaalsContact C-N 3.28Å; S235-L237 PolarHBondContact O-N 3.06Å; S235-R238 PolarHBondContact O-N 3.21Å
236R90.6Very high89.7Confident201 Ų20158.3 Ų58.376%0.75827%0.267SS*.Hα-helixtrans-63.6-33.4173.7-73.1174.9-173.5171-0.2112.9K232 L233 R238K232-R236 VanDerWaalsContact O-CG 3.32Å; K232-R236 WeakPolarHBondContact O-CG 3.28Å; K232-R236 PolarHBondContact O-N 2.66Å; L233-R236 WeakPolarHBondContact O-CB 3.39Å; L233-R236 PolarHBondContact O-N 3.39Å; L233-R236 VanDerWaalsContact O-N 3.08Å; R236-R238 PolarHBondContact O-N 3.31Å
237L92.7Very high90Very high104 Ų10456.4 Ų56.455%0.54526%0.259SS..THydrogen-bonded Turntrans-795.8174.3-66.2175000113.2F226 L233 A234 S235 M239F226-L237 HydrophobicContact CE1-CD1 3.99Å; F226-L237 HydrophobicContact CZ-CD1 3.96Å; L233-L237 HydrophobicContact CD1-CD1 4.4Å; L233-L237 HydrophobicContact CD1-CG 4.36Å; L233-L237 HydrophobicContact CG-CD1 4.1Å; L233-L237 HydrophobicContact CG-CG 4.47Å; L233-L237 WeakPolarHBondContact O-CG 3.35Å; L233-L237 PolarHBondContact O-N 2.89Å; A234-L237 CarbonylContact O-C 3.51Å; A234-L237 PolarHBondContact O-N 3.24Å; S235-L237 VanDerWaalsContact C-N 3.28Å; S235-L237 PolarHBondContact O-N 3.06Å; L237-M239 HydrophobicContact CB-CG 4.11Å; L237-M239 PolarHBondContact O-N 3.24Å
238R92.7Very high90.3Very high143 Ų14360 Ų6054%0.5428%0.275SS..THydrogen-bonded Turntrans57.429.9-179.9-53.7-171.8-177176.52.5113.7D111 A234 S235 R236D111-R238 HydrophobicContact CB-CB 4.44Å; D111-R238 WeakPolarHBondContact OD2-CA 3.14Å; D111-R238 WeakPolarHBondContact OD2-CB 3.37Å; D111-R238 WeakPolarHBondContact OD2-CG 3.49Å; A234-R238 PolarHBondContact O-N 3.26Å; S235-R238 PolarHBondContact O-N 3.21Å; R236-R238 PolarHBondContact O-N 3.31Å
239M92.8Very high90.9Very high24 Ų2458 Ų5812%0.11827%0.267CS..  trans-69150.6176.6-64.1-173.275.400110.6N108 L223 F226 V227 A234 L237N108-M239 PolarHBondContact ND2-O 2.88Å; N108-M239 VanDerWaalsContact ND2-O 3.12Å; L223-M239 HydrophobicContact CB-CE 4.3Å; L223-M239 HydrophobicContact CD2-CE 4.31Å; F226-M239 HydrophobicContact CD1-CE 4.3Å; F226-M239 HydrophobicContact CD1-SD 3.68Å; F226-M239 HydrophobicContact CE1-SD 3.63Å; V227-M239 HydrophobicContact CG2-CB 4.38Å; V227-M239 HydrophobicContact CG2-CE 3.73Å; V227-M239 HydrophobicContact CG2-SD 4Å; A234-M239 HydrophobicContact CB-CB 4.32Å; A234-M239 HydrophobicContact CB-CG 4.49Å; A234-M239 HydrophobicContact CB-SD 4.01Å; A234-M239 WeakPolarHBondContact O-CB 3.38Å; A234-M239 PolarHBondContact O-N 2.68Å; L237-M239 HydrophobicContact CB-CG 4.11Å; L237-M239 PolarHBondContact O-N 3.24Å
240R91.9Very high91.4Very high39 Ų3957.7 Ų57.715%0.14727%0.265CS..  trans-118.2139.1177.8-55.9-178.967179.27.3108.5D111 D112 R218 H219 E244 H247D111-R240 HydrophobicContact CB-CG 4.39Å; D111-R240 VanDerWaalsContact O-CD 3.22Å; D111-R240 WeakPolarHBondContact O-CD 3.28Å; D111-R240 WeakPolarHBondContact O-CG 3.45Å; D111-R240 PolarHBondContact O-NE 3.46Å; D112-R240 HydrophobicContact CB-CB 4.07Å; D112-R240 HydrophobicContact CB-CG 4.09Å; R218-R240 VanDerWaalsContact CD-O 3.25Å; R218-R240 WeakPolarHBondContact CD-O 3.44Å; H219-R240 PolarHBondContact CD2-O 3.49Å; H219-R240 PolarHBondContact NE2-O 2.95Å; R240-E244 IonicContact CZ-OE2 3.58Å; R240-E244 VanDerWaalsContact NH1-CD 3.34Å; R240-E244 IonicContact NH1-OE1 3.84Å; R240-E244 PolarHBondContact NH1-OE1 3Å; R240-E244 VanDerWaalsContact NH1-OE1 3.13Å; R240-E244 IonicContact NH1-OE2 3.4Å; R240-E244 PolarHBondContact NH1-OE2 3.18Å; R240-H247 PolarHBondContact NH2-CD2 2.87Å; R240-H247 PolarHBondContact NH2-CE1 3.1Å; R240-H247 PolarHBondContact NH2-ND1 2.8Å; R240-H247 PolarHBondContact NH2-NE2 3.13Å
241M90.1Very high91.8Very high43 Ų4354.8 Ų54.821%0.21225%0.252CS..  trans-92.4-37.3176.9-171165.867.400111F106 D112 T115 R218 F228F106-M241 HydrophobicContact CD1-CB 4.11Å; F106-M241 HydrophobicContact CD1-CE 4.31Å; F106-M241 HydrophobicContact CD1-SD 4.08Å; F106-M241 HydrophobicContact CE1-CB 3.94Å; D112-M241 PolarHBondContact OD2-N 3.47Å; T115-M241 HydrophobicContact CG2-CB 4.26Å; T115-M241 HydrophobicContact CG2-CE 4.04Å; R218-M241 WeakPolarHBondContact CB-O 3.28Å; F228-M241 HydrophobicContact CE1-SD 4.39Å; F228-M241 HydrophobicContact CZ-SD 4.03Å
242M91.7Very high92Very high18 Ų1860.3 Ų60.39%0.08927%0.27CS..SBendtrans-73.8135.5-174.8-65-6497.300112.8D112 L114 T115 R218 H247 F305D112-M242 PolarHBondContact OD2-N 3.05Å; L114-M242 HydrophobicContact CB-CG 4.07Å; T115-M242 HydrophobicContact CG2-CG 4.25Å; R218-M242 VanDerWaalsContact CD-O 3.25Å; R218-M242 WeakPolarHBondContact CD-O 3.32Å; R218-M242 PolarHBondContact NH1-O 3.46Å; M242-H247 HydrophobicContact CB-CB 4.49Å; M242-F305 HydrophobicContact SD-CE1 3.81Å; M242-F305 HydrophobicContact SD-CE2 4.23Å; M242-F305 HydrophobicContact SD-CZ 3.43Å; M242-F305 WeakPolarHBondContact SD-CZ 3.42Å
243P92.6Very high92.2Very high10 Ų1053.9 Ų53.97%0.06524%0.243CC..  trans-51.8143.4166.7-25.134.8000111.4D216 D245 V246 H247D216-P243 HydrophobicContact CB-CG 4.17Å; P243-D245 WeakPolarHBondContact CB-OD1 3.03Å; P243-V246 HydrophobicContact CB-CB 4.17Å; P243-V246 HydrophobicContact CB-CG2 3.94Å; P243-V246 HydrophobicContact CG-CG2 4.21Å; P243-V246 PolarHBondContact O-N 3.24Å; P243-H247 WeakPolarHBondContact O-CB 3.33Å; P243-H247 PolarHBondContact O-N 2.97Å
244E92.6Very high92.2Very high67 Ų6750.2 Ų50.231%0.31322%0.224SC..Hα-helixtrans-65.5-43.4-171.6-170.860.9-143.200112.3R218 R240 H247 Q248R218-E244 IonicContact CZ-OE2 3.06Å; R218-E244 VanDerWaalsContact CZ-OE2 3.24Å; R218-E244 IonicContact NH1-OE2 3.45Å; R218-E244 PolarHBondContact NH1-OE2 3.29Å; R218-E244 IonicContact NH2-OE2 2.78Å; R218-E244 PolarHBondContact NH2-OE2 3.05Å; R240-E244 IonicContact CZ-OE2 3.58Å; R240-E244 VanDerWaalsContact NH1-CD 3.34Å; R240-E244 IonicContact NH1-OE1 3.84Å; R240-E244 PolarHBondContact NH1-OE1 3Å; R240-E244 VanDerWaalsContact NH1-OE1 3.13Å; R240-E244 IonicContact NH1-OE2 3.4Å; R240-E244 PolarHBondContact NH1-OE2 3.18Å; E244-H247 WeakPolarHBondContact O-CB 3.22Å; E244-H247 PolarHBondContact O-N 3.33Å; E244-H247 IonicContact OE1-CD2 3.82Å; E244-Q248 HydrophobicContact CG-CG 4.34Å; E244-Q248 VanDerWaalsContact O-CG 3.27Å; E244-Q248 WeakPolarHBondContact O-CG 3.47Å; E244-Q248 PolarHBondContact O-N 2.93Å; E244-Q248 PolarHBondContact OE1-NE2 3.05Å
245D93.9Very high92.2Very high58 Ų5853.7 Ų53.731%0.3124%0.242SC..Hα-helixtrans-62.4-44.3177.956.3-16.8000112.1M209 K212 P243 H247 Q248 F249M209-D245 HydrophobicContact SD-CB 4.42Å; K212-D245 WeakPolarHBondContact CD-OD2 3.22Å; K212-D245 IonicContact NZ-OD2 3.78Å; K212-D245 PolarHBondContact NZ-OD2 3.13Å; P243-D245 WeakPolarHBondContact CB-OD1 3.03Å; D245-H247 VanDerWaalsContact C-N 3.34Å; D245-H247 PolarHBondContact O-N 3.39Å; D245-Q248 PolarHBondContact O-N 3.41Å; D245-F249 VanDerWaalsContact O-CB 3.31Å; D245-F249 WeakPolarHBondContact O-CB 3.36Å; D245-F249 PolarHBondContact O-N 3Å
246V93.3Very high92.3Very high0 Ų056.8 Ų56.80%026%0.256CS..Hα-helixtrans-58.5-47.7172.8175.10000110.2M209 K212 V213 P243 Q248 F249 F250 F305M209-V246 HydrophobicContact SD-CG2 4.3Å; K212-V246 HydrophobicContact CB-CG2 3.82Å; V213-V246 HydrophobicContact CG2-CG1 3.88Å; P243-V246 HydrophobicContact CB-CB 4.17Å; P243-V246 HydrophobicContact CB-CG2 3.94Å; P243-V246 HydrophobicContact CG-CG2 4.21Å; P243-V246 PolarHBondContact O-N 3.24Å; V246-Q248 PolarHBondContact O-N 2.89Å; V246-F249 PolarHBondContact O-N 3.12Å; V246-F250 HydrophobicContact CG1-CD2 3.92Å; V246-F250 HydrophobicContact CG1-CE2 3.96Å; V246-F250 WeakPolarHBondContact O-CD2 3.38Å; V246-F250 PolarHBondContact O-N 3.34Å; V246-F250 VanDerWaalsContact O-N 3.14Å; V246-F305 HydrophobicContact CG1-CE2 3.91Å
247H93.8Very high92.1Very high17 Ų1748 Ų488%0.07922%0.224CC..Hα-helixtrans-58.1-51.9177.8172.184.1000112.3L114 R240 M242 P243 E244 D245 F249 F250 M251L114-H247 HydrophobicContact CD1-CB 4.33Å; R240-H247 PolarHBondContact NH2-CD2 2.87Å; R240-H247 PolarHBondContact NH2-CE1 3.1Å; R240-H247 PolarHBondContact NH2-ND1 2.8Å; R240-H247 PolarHBondContact NH2-NE2 3.13Å; M242-H247 HydrophobicContact CB-CB 4.49Å; P243-H247 WeakPolarHBondContact O-CB 3.33Å; P243-H247 PolarHBondContact O-N 2.97Å; E244-H247 WeakPolarHBondContact O-CB 3.22Å; E244-H247 PolarHBondContact O-N 3.33Å; E244-H247 IonicContact OE1-CD2 3.82Å; D245-H247 VanDerWaalsContact C-N 3.34Å; D245-H247 PolarHBondContact O-N 3.39Å; H247-F249 VanDerWaalsContact C-N 3.27Å; H247-F249 PolarHBondContact O-N 3.22Å; H247-F250 PolarHBondContact O-N 3.02Å; H247-M251 VanDerWaalsContact CE1-CG 3.45Å; H247-M251 WeakPolarHBondContact CE1-CG 3.15Å; H247-M251 WeakPolarHBondContact O-CB 3.4Å; H247-M251 VanDerWaalsContact O-CG 3.27Å; H247-M251 WeakPolarHBondContact O-CG 3.43Å; H247-M251 PolarHBondContact O-N 2.9Å
248Q94.6Very high91.8Very high77 Ų7743.6 Ų43.636%0.3620%0.201SC..Hα-helixtrans-63.5-34.6-179.2-66.6-58.8-29.100112E244 D245 V246 R252E244-Q248 HydrophobicContact CG-CG 4.34Å; E244-Q248 VanDerWaalsContact O-CG 3.27Å; E244-Q248 WeakPolarHBondContact O-CG 3.47Å; E244-Q248 PolarHBondContact O-N 2.93Å; E244-Q248 PolarHBondContact OE1-NE2 3.05Å; D245-Q248 PolarHBondContact O-N 3.41Å; V246-Q248 PolarHBondContact O-N 2.89Å; Q248-R252 VanDerWaalsContact O-CB 3.29Å; Q248-R252 WeakPolarHBondContact O-CB 3.46Å; Q248-R252 VanDerWaalsContact O-CG 3.24Å; Q248-R252 WeakPolarHBondContact O-CG 3.34Å; Q248-R252 PolarHBondContact O-N 3.49Å; Q248-R252 PolarHBondContact O-NE 3.43Å; Q248-R252 VanDerWaalsContact O-NE 3.11Å
249F93.3Very high91.6Very high24 Ų2439.3 Ų39.311%0.10520%0.197CC..Hα-helixtrans-61.8-56.8176175.5-99.7000111.7D205 F206 M209 D245 V246 H247 M251 R252 L253D205-F249 HydrophobicContact CB-CD2 4.4Å; D205-F249 HydrophobicContact CB-CE2 3.73Å; D205-F249 HydrophobicContact CB-CZ 4.39Å; F206-F249 HydrophobicContact CD1-CE1 4.2Å; F206-F249 HydrophobicContact CD1-CZ 4.04Å; F206-F249 AromaticContact CD2-CZ 3.93Å; F206-F249 HydrophobicContact CD2-CZ 3.93Å; F206-F249 HydrophobicContact CE1-CE1 4.3Å; F206-F249 HydrophobicContact CE1-CZ 4.14Å; F206-F249 HydrophobicContact CE2-CZ 4.02Å; F206-F249 HydrophobicContact CG-CE1 4.49Å; F206-F249 AromaticContact CG-CZ 3.94Å; F206-F249 HydrophobicContact CG-CZ 3.94Å; F206-F249 HydrophobicContact CZ-CZ 4.13Å; M209-F249 HydrophobicContact CB-CD1 3.84Å; M209-F249 HydrophobicContact CB-CE1 4.19Å; M209-F249 HydrophobicContact CB-CG 4.17Å; M209-F249 HydrophobicContact CG-CB 3.93Å; M209-F249 HydrophobicContact CG-CD1 3.85Å; M209-F249 HydrophobicContact CG-CD2 3.98Å; M209-F249 HydrophobicContact CG-CE1 4.36Å; M209-F249 HydrophobicContact CG-CE2 4.48Å; M209-F249 HydrophobicContact CG-CG 3.64Å; M209-F249 HydrophobicContact SD-CB 4.32Å; D245-F249 VanDerWaalsContact O-CB 3.31Å; D245-F249 WeakPolarHBondContact O-CB 3.36Å; D245-F249 PolarHBondContact O-N 3Å; V246-F249 PolarHBondContact O-N 3.12Å; H247-F249 VanDerWaalsContact C-N 3.27Å; H247-F249 PolarHBondContact O-N 3.22Å; F249-M251 PolarHBondContact O-N 3.06Å; F249-R252 PolarHBondContact O-N 2.94Å; F249-L253 HydrophobicContact CE1-CD2 4.3Å; F249-L253 VanDerWaalsContact O-CB 3.29Å; F249-L253 WeakPolarHBondContact O-CB 3.39Å; F249-L253 PolarHBondContact O-N 3.04Å
250F92.8Very high91.3Very high0 Ų041.6 Ų41.60%021%0.209CC..Hα-helixtrans-68.5-34.6-176.6-76.6-78.2000112.9L114 M209 V246 H247 L253 V254 V304 F305 Y308L114-F250 HydrophobicContact CD1-CB 3.99Å; L114-F250 HydrophobicContact CD1-CD2 4.46Å; L114-F250 HydrophobicContact CD2-CB 4.18Å; M209-F250 HydrophobicContact CB-CE2 4.49Å; V246-F250 HydrophobicContact CG1-CD2 3.92Å; V246-F250 HydrophobicContact CG1-CE2 3.96Å; V246-F250 WeakPolarHBondContact O-CD2 3.38Å; V246-F250 PolarHBondContact O-N 3.34Å; V246-F250 VanDerWaalsContact O-N 3.14Å; H247-F250 PolarHBondContact O-N 3.02Å; F250-L253 HydrophobicContact CD1-CD2 4.25Å; F250-V254 WeakPolarHBondContact O-CB 3.21Å; F250-V254 WeakPolarHBondContact O-CG2 3.49Å; F250-V254 PolarHBondContact O-N 3.41Å; F250-V304 HydrophobicContact CD1-CG1 4.39Å; F250-F305 HydrophobicContact CD1-CB 4.25Å; F250-F305 HydrophobicContact CD1-CD2 4.36Å; F250-F305 AromaticContact CD2-CD2 3.53Å; F250-F305 HydrophobicContact CD2-CD2 3.53Å; F250-F305 HydrophobicContact CD2-CE2 4.18Å; F250-F305 HydrophobicContact CE1-CD2 4.4Å; F250-F305 AromaticContact CE2-CD2 3.6Å; F250-F305 HydrophobicContact CE2-CD2 3.6Å; F250-F305 HydrophobicContact CE2-CE2 4.03Å; F250-F305 HydrophobicContact CG-CB 4.22Å; F250-F305 AromaticContact CG-CD2 3.96Å; F250-F305 HydrophobicContact CG-CD2 3.96Å; F250-F305 HydrophobicContact CZ-CD2 4.06Å; F250-Y308 AromaticContact CE1-CD1 3.8Å; F250-Y308 HydrophobicContact CE1-CD1 3.8Å; F250-Y308 HydrophobicContact CE1-CG 4.05Å; F250-Y308 AromaticContact CZ-CD1 3.41Å; F250-Y308 HydrophobicContact CZ-CD1 3.41Å; F250-Y308 VanDerWaalsContact CZ-CD1 3.41Å; F250-Y308 AromaticContact CZ-CE1 3.88Å; F250-Y308 HydrophobicContact CZ-CE1 3.88Å; F250-Y308 HydrophobicContact CZ-CG 4.14Å
251M94.2Very high91Very high25 Ų2540.6 Ų40.612%0.12321%0.205CC..Hα-helixtrans-64-45.4173.9-70.3-57.9-60.100111.6L114 H247 F249 N255 A301L114-M251 HydrophobicContact CD2-SD 4.18Å; H247-M251 VanDerWaalsContact CE1-CG 3.45Å; H247-M251 WeakPolarHBondContact CE1-CG 3.15Å; H247-M251 WeakPolarHBondContact O-CB 3.4Å; H247-M251 VanDerWaalsContact O-CG 3.27Å; H247-M251 WeakPolarHBondContact O-CG 3.43Å; H247-M251 PolarHBondContact O-N 2.9Å; F249-M251 PolarHBondContact O-N 3.06Å; M251-N255 PolarHBondContact O-N 3.47Å; M251-N255 VanDerWaalsContact O-N 3.15Å; M251-N255 PolarHBondContact O-ND2 2.96Å; M251-A301 HydrophobicContact CE-CB 4.46Å; M251-A301 HydrophobicContact SD-CB 3.52Å; M251-A301 VanDerWaalsContact SD-CB 3.52Å
252R93.5Very high90.7Very high143 Ų14343.8 Ų43.854%0.5422%0.219SC..Hα-helixtrans-64.9-49177.1-75.9-177.7-65-175.84.5111.6Q248 F249 V254 N255 D256Q248-R252 VanDerWaalsContact O-CB 3.29Å; Q248-R252 WeakPolarHBondContact O-CB 3.46Å; Q248-R252 VanDerWaalsContact O-CG 3.24Å; Q248-R252 WeakPolarHBondContact O-CG 3.34Å; Q248-R252 PolarHBondContact O-N 3.49Å; Q248-R252 PolarHBondContact O-NE 3.43Å; Q248-R252 VanDerWaalsContact O-NE 3.11Å; F249-R252 PolarHBondContact O-N 2.94Å; R252-V254 PolarHBondContact O-N 3.44Å; R252-V254 VanDerWaalsContact O-N 3.15Å; R252-N255 PolarHBondContact O-N 3.25Å; R252-D256 WeakPolarHBondContact O-CB 3.29Å; R252-D256 PolarHBondContact O-N 2.89Å
253L89.8Confident90.5Very high22 Ų2251.7 Ų51.712%0.11525%0.248CC..Hα-helixtrans-48.4-47.9178.8174.763.6000112.1I194 F206 F249 F250 T257I194-L253 HydrophobicContact CD1-CD1 3.6Å; I194-L253 HydrophobicContact CD1-CG 4.49Å; F206-L253 HydrophobicContact CE1-CD1 4.49Å; F206-L253 HydrophobicContact CE1-CD2 3.57Å; F206-L253 HydrophobicContact CE2-CD1 4.3Å; F206-L253 HydrophobicContact CZ-CD1 3.62Å; F206-L253 HydrophobicContact CZ-CD2 3.55Å; F206-L253 HydrophobicContact CZ-CG 4.24Å; F249-L253 HydrophobicContact CE1-CD2 4.3Å; F249-L253 VanDerWaalsContact O-CB 3.29Å; F249-L253 WeakPolarHBondContact O-CB 3.39Å; F249-L253 PolarHBondContact O-N 3.04Å; F250-L253 HydrophobicContact CD1-CD2 4.25Å; L253-T257 VanDerWaalsContact O-CB 3.28Å; L253-T257 WeakPolarHBondContact O-CB 3.2Å; L253-T257 PolarHBondContact O-N 3.01Å; L253-T257 PolarHBondContact O-OG1 3.32Å
254V90.3Very high90.1Very high0 Ų056.6 Ų56.60%027%0.27CS..Hα-helixtrans-69.1-46.1-178.3169.40000111.4F250 R252 T257 I258 M272 I297 L300 A301 V304F250-V254 WeakPolarHBondContact O-CB 3.21Å; F250-V254 WeakPolarHBondContact O-CG2 3.49Å; F250-V254 PolarHBondContact O-N 3.41Å; R252-V254 PolarHBondContact O-N 3.44Å; R252-V254 VanDerWaalsContact O-N 3.15Å; V254-T257 PolarHBondContact O-N 2.69Å; V254-I258 HydrophobicContact CG1-CD1 3.89Å; V254-I258 VanDerWaalsContact O-CG1 3.29Å; V254-I258 WeakPolarHBondContact O-CG1 3.24Å; V254-I258 PolarHBondContact O-N 3.49Å; V254-M272 HydrophobicContact CG2-CE 4.42Å; V254-I297 HydrophobicContact CG1-CD1 3.71Å; V254-L300 HydrophobicContact CB-CD2 4.48Å; V254-L300 HydrophobicContact CG1-CD2 3.34Å; V254-L300 HydrophobicContact CG2-CD2 4.37Å; V254-A301 HydrophobicContact CB-CB 4.23Å; V254-A301 HydrophobicContact CG1-CB 4.32Å; V254-A301 HydrophobicContact CG2-CB 3.95Å; V254-V304 HydrophobicContact CG2-CB 3.95Å; V254-V304 HydrophobicContact CG2-CG1 3.86Å; V254-V304 HydrophobicContact CG2-CG2 4.03Å
255N91.1Very high89.4Confident73 Ų7360.1 Ų60.139%0.3929%0.291SS..Hα-helixtrans-60.2-47.5177.3-78.7-57.6000111.6M251 R252 T257 I258 A259 I297M251-N255 PolarHBondContact O-N 3.47Å; M251-N255 VanDerWaalsContact O-N 3.15Å; M251-N255 PolarHBondContact O-ND2 2.96Å; R252-N255 PolarHBondContact O-N 3.25Å; N255-T257 VanDerWaalsContact C-N 3.34Å; N255-T257 PolarHBondContact O-N 3.32Å; N255-I258 PolarHBondContact O-N 3.13Å; N255-A259 WeakPolarHBondContact O-CB 3.36Å; N255-A259 PolarHBondContact O-N 2.83Å; N255-I297 WeakPolarHBondContact OD1-CG1 3.49Å
256D90Very high88.6Confident105 Ų10561.5 Ų61.556%0.56130%0.295SS*.Hα-helixtrans-64.5-40.6-179-63.5-19.6000111R252 A259 L260R252-D256 WeakPolarHBondContact O-CB 3.29Å; R252-D256 PolarHBondContact O-N 2.89Å; D256-A259 PolarHBondContact O-N 2.93Å; D256-L260 VanDerWaalsContact O-CB 3.24Å; D256-L260 WeakPolarHBondContact O-CB 3.35Å; D256-L260 PolarHBondContact O-N 3.13Å
257T87.4Confident87.6Confident15 Ų1568.7 Ų68.79%0.09233%0.326CS..Hα-helixtrans-65.7-41.6177.9-58.10000111.9L253 V254 N255 R261 M272L253-T257 VanDerWaalsContact O-CB 3.28Å; L253-T257 WeakPolarHBondContact O-CB 3.2Å; L253-T257 PolarHBondContact O-N 3.01Å; L253-T257 PolarHBondContact O-OG1 3.32Å; V254-T257 PolarHBondContact O-N 2.69Å; N255-T257 VanDerWaalsContact C-N 3.34Å; N255-T257 PolarHBondContact O-N 3.32Å; T257-R261 WeakPolarHBondContact O-CG 3.24Å; T257-R261 PolarHBondContact O-N 2.87Å; T257-R261 VanDerWaalsContact O-N 3.12Å; T257-M272 HydrophobicContact CG2-CE 4.05Å; T257-M272 HydrophobicContact CG2-CG 3.85Å; T257-M272 HydrophobicContact CG2-SD 4.39Å
258I86.4Confident86.5Confident12 Ų1271.7 Ų71.76%0.06234%0.337CS..Hα-helixtrans-65.9-50176.8-69.3170.5000109.9V254 N255 L260 R261 E262 I276 I297 L300V254-I258 HydrophobicContact CG1-CD1 3.89Å; V254-I258 VanDerWaalsContact O-CG1 3.29Å; V254-I258 WeakPolarHBondContact O-CG1 3.24Å; V254-I258 PolarHBondContact O-N 3.49Å; N255-I258 PolarHBondContact O-N 3.13Å; I258-L260 VanDerWaalsContact C-N 3.29Å; I258-L260 PolarHBondContact O-N 3.16Å; I258-R261 PolarHBondContact O-N 3.17Å; I258-E262 HydrophobicContact CG2-CG 4.27Å; I258-E262 WeakPolarHBondContact O-CB 3.27Å; I258-E262 WeakPolarHBondContact O-CG 3.42Å; I258-E262 PolarHBondContact O-N 2.8Å; I258-I276 HydrophobicContact CG1-CD1 4.12Å; I258-I276 HydrophobicContact CG1-CG1 4.02Å; I258-I297 HydrophobicContact CD1-CD1 3.47Å; I258-I297 VanDerWaalsContact CD1-CD1 3.47Å; I258-L300 HydrophobicContact CD1-CD1 4.17Å; I258-L300 HydrophobicContact CD1-CD2 4.32Å
259A88Confident85.3Confident54 Ų5473.4 Ų73.445%0.44635%0.348SS..Hα-helixtrans-58.7-41.2-18000000112N255 D256 R263N255-A259 WeakPolarHBondContact O-CB 3.36Å; N255-A259 PolarHBondContact O-N 2.83Å; D256-A259 PolarHBondContact O-N 2.93Å; A259-R263 VanDerWaalsContact O-CB 3.25Å; A259-R263 WeakPolarHBondContact O-CB 3.37Å; A259-R263 PolarHBondContact O-N 3.06Å
260L86.3Confident84.6Confident71 Ų7173 Ų7337%0.37235%0.347SS..Hα-helixtrans-62.2-49176.1-179.267.7000111.7D256 I258 E262 R263 E264 F266D256-L260 VanDerWaalsContact O-CB 3.24Å; D256-L260 WeakPolarHBondContact O-CB 3.35Å; D256-L260 PolarHBondContact O-N 3.13Å; I258-L260 VanDerWaalsContact C-N 3.29Å; I258-L260 PolarHBondContact O-N 3.16Å; L260-E262 PolarHBondContact O-N 3.08Å; L260-R263 PolarHBondContact O-N 2.97Å; L260-E264 HydrophobicContact CD1-CG 3.75Å; L260-E264 HydrophobicContact CG-CG 4.3Å; L260-E264 WeakPolarHBondContact O-CB 3.22Å; L260-E264 WeakPolarHBondContact O-CG 3.45Å; L260-E264 PolarHBondContact O-N 3.03Å; L260-F266 HydrophobicContact CG-CE1 4.33Å
261R85.8Confident84Confident18 Ų1873.4 Ų73.47%0.06835%0.349CS..Hα-helixtrans-66.2-37.8-178.5-72.3177.9-171.7-149.10.5112.4F192 T257 I258 N265 F266 D270F192-R261 PolarHBondContact O-NH2 3.31Å; T257-R261 WeakPolarHBondContact O-CG 3.24Å; T257-R261 PolarHBondContact O-N 2.87Å; T257-R261 VanDerWaalsContact O-N 3.12Å; I258-R261 PolarHBondContact O-N 3.17Å; R261-N265 WeakPolarHBondContact O-CA 3.45Å; R261-N265 PolarHBondContact O-N 3.07Å; R261-F266 HydrophobicContact CG-CE1 3.94Å; R261-F266 HydrophobicContact CG-CE2 4.28Å; R261-F266 HydrophobicContact CG-CZ 3.74Å; R261-D270 IonicContact CZ-OD1 3.17Å; R261-D270 IonicContact CZ-OD2 2.9Å; R261-D270 IonicContact NH1-OD1 3.05Å; R261-D270 PolarHBondContact NH1-OD1 3.33Å; R261-D270 IonicContact NH1-OD2 3.89Å; R261-D270 PolarHBondContact NH1-OD2 2.68Å; R261-D270 IonicContact NH2-OD1 2.97Å; R261-D270 PolarHBondContact NH2-OD1 2.7Å; R261-D270 IonicContact NH2-OD2 3.43Å; R261-D270 PolarHBondContact NH2-OD2 3.45Å
262E83.3Confident83.5Confident111 Ų11172.2 Ų72.252%0.51934%0.343SS..Hα-helixtrans-66-41.5174.7-72.1178.8169.600111.4I258 L260I258-E262 HydrophobicContact CG2-CG 4.27Å; I258-E262 WeakPolarHBondContact O-CB 3.27Å; I258-E262 WeakPolarHBondContact O-CG 3.42Å; I258-E262 PolarHBondContact O-N 2.8Å; L260-E262 PolarHBondContact O-N 3.08Å
263R87.1Confident82.9Confident184 Ų18466 Ų6669%0.69432%0.321SS*.Hα-helixtrans-66.9-45.5178.6-173.9-175.275.2-173.14.2113A259 L260A259-R263 VanDerWaalsContact O-CB 3.25Å; A259-R263 WeakPolarHBondContact O-CB 3.37Å; A259-R263 PolarHBondContact O-N 3.06Å; L260-R263 PolarHBondContact O-N 2.97Å
264E85.4Confident82.4Confident112 Ų11267 Ų6752%0.52333%0.326SS..Hα-helixtrans-89.9-6.9-171.8-59-105.815700112.2L260 F266L260-E264 HydrophobicContact CD1-CG 3.75Å; L260-E264 HydrophobicContact CG-CG 4.3Å; L260-E264 WeakPolarHBondContact O-CB 3.22Å; L260-E264 WeakPolarHBondContact O-CG 3.45Å; L260-E264 PolarHBondContact O-N 3.03Å; E264-F266 HydrophobicContact CB-CD1 3.61Å; E264-F266 HydrophobicContact CB-CE1 4.11Å; E264-F266 HydrophobicContact CG-CD1 4.49Å; E264-F266 PolarHBondContact O-N 3.06Å; E264-F266 VanDerWaalsContact O-N 3.09Å
265N78.4Confident82Confident142 Ų14267 Ų6776%0.75933%0.326SS*.THydrogen-bonded Turntrans49.333.6-179.1-164.233.5000114.2R261R261-N265 WeakPolarHBondContact O-CA 3.45Å; R261-N265 PolarHBondContact O-N 3.07Å
266F76.3Confident81.5Confident87 Ų8764.1 Ų64.138%0.38231%0.31SS..  trans-101.5143.9174.882.7-87.6000111L260 R261 E264 R268L260-F266 HydrophobicContact CG-CE1 4.33Å; R261-F266 HydrophobicContact CG-CE1 3.94Å; R261-F266 HydrophobicContact CG-CE2 4.28Å; R261-F266 HydrophobicContact CG-CZ 3.74Å; E264-F266 HydrophobicContact CB-CD1 3.61Å; E264-F266 HydrophobicContact CB-CE1 4.11Å; E264-F266 HydrophobicContact CG-CD1 4.49Å; E264-F266 PolarHBondContact O-N 3.06Å; E264-F266 VanDerWaalsContact O-N 3.09Å; F266-R268 HydrophobicContact CE2-CB 4.32Å
267K71.1Confident81Confident150 Ų15061.7 Ų61.765%0.65230%0.296SS*.  trans-113.1128.3173.3-67.1-175.2178.4-174.80109.2
268R71.7Confident80.4Confident81 Ų8161.6 Ų61.631%0.30629%0.294SS..  trans-110.5131.8168.2-174.9171.2176.91604.5107.6T189 G193 F266 D270 N273T189-R268 PolarHBondContact O-NH2 3.15Å; G193-R268 VanDerWaalsContact C-NH1 3.31Å; G193-R268 PolarHBondContact O-NH1 3.46Å; F266-R268 HydrophobicContact CE2-CB 4.32Å; R268-D270 WeakPolarHBondContact CB-OD2 3.45Å; R268-D270 VanDerWaalsContact CD-OD2 3.28Å; R268-D270 WeakPolarHBondContact CD-OD2 3.28Å; R268-D270 HydrophobicContact CG-CB 4.33Å; R268-D270 VanDerWaalsContact CG-OD2 3.3Å; R268-D270 WeakPolarHBondContact CG-OD2 3.5Å; R268-D270 IonicContact NE-OD2 2.58Å; R268-D270 PolarHBondContact O-N 3.15Å; R268-N273 WeakPolarHBondContact O-CB 3.33Å
269N69.3Low79.9Confident112 Ų11264.7 Ų64.760%0.59931%0.307SS*.  trans-77.563-178.8-72.3-36.9000111.5F144F144-N269 HydrophobicContact CE1-CB 3.84Å; F144-N269 WeakPolarHBondContact CE1-O 3.19Å; F144-N269 HydrophobicContact CZ-CB 3.78Å
270D78.8Confident79.2Confident16 Ų1667.7 Ų67.79%0.08631%0.312CS..SBendtrans-116.3177.9179.557.732.9000112.2G193 R261 R268 M272 N273 L274G193-D270 WeakPolarHBondContact CA-OD2 3.44Å; R261-D270 IonicContact CZ-OD1 3.17Å; R261-D270 IonicContact CZ-OD2 2.9Å; R261-D270 IonicContact NH1-OD1 3.05Å; R261-D270 PolarHBondContact NH1-OD1 3.33Å; R261-D270 IonicContact NH1-OD2 3.89Å; R261-D270 PolarHBondContact NH1-OD2 2.68Å; R261-D270 IonicContact NH2-OD1 2.97Å; R261-D270 PolarHBondContact NH2-OD1 2.7Å; R261-D270 IonicContact NH2-OD2 3.43Å; R261-D270 PolarHBondContact NH2-OD2 3.45Å; R268-D270 WeakPolarHBondContact CB-OD2 3.45Å; R268-D270 VanDerWaalsContact CD-OD2 3.28Å; R268-D270 WeakPolarHBondContact CD-OD2 3.28Å; R268-D270 HydrophobicContact CG-CB 4.33Å; R268-D270 VanDerWaalsContact CG-OD2 3.3Å; R268-D270 WeakPolarHBondContact CG-OD2 3.5Å; R268-D270 IonicContact NE-OD2 2.58Å; R268-D270 PolarHBondContact O-N 3.15Å; D270-M272 VanDerWaalsContact C-N 3.31Å; D270-M272 PolarHBondContact O-N 3.12Å; D270-M272 WeakPolarHBondContact OD1-CB 3.29Å; D270-M272 PolarHBondContact OD1-N 2.9Å; D270-N273 PolarHBondContact O-N 2.81Å; D270-N273 WeakPolarHBondContact OD1-CB 3.21Å; D270-N273 PolarHBondContact OD1-N 2.93Å; D270-L274 PolarHBondContact O-N 3.01Å
271F79.7Confident78.3Confident9 Ų970.4 Ų70.44%0.03932%0.321CS..Hα-helixtrans-63.8-37179.2177.3-117.7000112L133 T136 A191 F192 N273 L274 L275 Q303 F307L133-F271 HydrophobicContact CD2-CE2 3.62Å; L133-F271 HydrophobicContact CD2-CZ 3.72Å; T136-F271 HydrophobicContact CG2-CB 4.45Å; T136-F271 HydrophobicContact CG2-CD2 3.52Å; T136-F271 HydrophobicContact CG2-CE2 4.17Å; T136-F271 HydrophobicContact CG2-CG 4.37Å; A191-F271 HydrophobicContact CB-CB 4.01Å; A191-F271 HydrophobicContact CB-CD1 4.29Å; A191-F271 WeakPolarHBondContact O-CA 3.3Å; A191-F271 VanDerWaalsContact O-CB 3.26Å; A191-F271 WeakPolarHBondContact O-CB 3.44Å; A191-F271 PolarHBondContact O-N 3.41Å; A191-F271 VanDerWaalsContact O-N 3.09Å; F192-F271 HydrophobicContact CE1-CD1 4.25Å; F271-N273 VanDerWaalsContact C-N 3.32Å; F271-N273 PolarHBondContact O-N 2.98Å; F271-L274 HydrophobicContact CD2-CD2 4.33Å; F271-L274 HydrophobicContact CE2-CD2 4.5Å; F271-L274 WeakPolarHBondContact O-CB 3.28Å; F271-L274 PolarHBondContact O-N 3.46Å; F271-L275 HydrophobicContact CD1-CD1 4.03Å; F271-L275 HydrophobicContact CD1-CG 4.44Å; F271-L275 HydrophobicContact CE1-CD1 3.58Å; F271-L275 HydrophobicContact CE1-CD2 4.31Å; F271-L275 HydrophobicContact CE1-CG 4.09Å; F271-L275 HydrophobicContact CE2-CD2 4Å; F271-L275 HydrophobicContact CE2-CG 4.21Å; F271-L275 HydrophobicContact CZ-CD1 3.9Å; F271-L275 HydrophobicContact CZ-CD2 3.74Å; F271-L275 HydrophobicContact CZ-CG 3.96Å; F271-L275 WeakPolarHBondContact O-CG 3.24Å; F271-L275 PolarHBondContact O-N 3.48Å; F271-Q303 HydrophobicContact CZ-CB 4.5Å; F271-F307 HydrophobicContact CD1-CD2 4.45Å; F271-F307 HydrophobicContact CE1-CB 4.08Å; F271-F307 AromaticContact CE1-CD2 3.33Å; F271-F307 HydrophobicContact CE1-CD2 3.33Å; F271-F307 AromaticContact CE1-CE2 3.95Å; F271-F307 HydrophobicContact CE1-CE2 3.95Å; F271-F307 AromaticContact CE1-CG 3.81Å; F271-F307 HydrophobicContact CE1-CG 3.81Å; F271-F307 HydrophobicContact CE2-CD2 4.36Å; F271-F307 HydrophobicContact CE2-CE2 4.2Å; F271-F307 AromaticContact CZ-CD2 3.27Å; F271-F307 HydrophobicContact CZ-CD2 3.27Å; F271-F307 AromaticContact CZ-CE2 3.36Å; F271-F307 HydrophobicContact CZ-CE2 3.36Å; F271-F307 HydrophobicContact CZ-CG 4.03Å; F271-F307 HydrophobicContact CZ-CZ 4.14Å
272M83.7Confident77.1Confident0 Ų071.4 Ų71.40%034%0.337CS..Hα-helixtrans-58.6-41.9174.5-176.867.278.100112A191 F192 V254 T257 D270 L274 L275 I276 L300 V304A191-M272 PolarHBondContact O-N 2.89Å; F192-M272 HydrophobicContact CD1-CE 4.29Å; V254-M272 HydrophobicContact CG2-CE 4.42Å; T257-M272 HydrophobicContact CG2-CE 4.05Å; T257-M272 HydrophobicContact CG2-CG 3.85Å; T257-M272 HydrophobicContact CG2-SD 4.39Å; D270-M272 VanDerWaalsContact C-N 3.31Å; D270-M272 PolarHBondContact O-N 3.12Å; D270-M272 WeakPolarHBondContact OD1-CB 3.29Å; D270-M272 PolarHBondContact OD1-N 2.9Å; M272-L274 VanDerWaalsContact C-N 3.34Å; M272-L274 PolarHBondContact O-N 3.18Å; M272-L275 PolarHBondContact O-N 3.29Å; M272-L275 VanDerWaalsContact O-N 3.16Å; M272-I276 HydrophobicContact CG-CD1 3.92Å; M272-I276 HydrophobicContact CG-CG1 4.46Å; M272-I276 VanDerWaalsContact O-CG1 3.29Å; M272-I276 WeakPolarHBondContact O-CG1 3.34Å; M272-I276 PolarHBondContact O-N 3.49Å; M272-L300 HydrophobicContact SD-CD2 3.89Å; M272-V304 HydrophobicContact CE-CG1 4.41Å; M272-V304 HydrophobicContact CE-CG2 3.74Å; M272-V304 HydrophobicContact SD-CG2 4.19Å
273N82.2Confident76.1Confident13 Ų1374.5 Ų74.57%0.0734%0.344CS..Hα-helixtrans-65-38.5177.8-174.179.6000112.1R268 D270 F271 L275 I276 E277R268-N273 WeakPolarHBondContact O-CB 3.33Å; D270-N273 PolarHBondContact O-N 2.81Å; D270-N273 WeakPolarHBondContact OD1-CB 3.21Å; D270-N273 PolarHBondContact OD1-N 2.93Å; F271-N273 VanDerWaalsContact C-N 3.32Å; F271-N273 PolarHBondContact O-N 2.98Å; N273-L275 VanDerWaalsContact C-N 3.32Å; N273-L275 PolarHBondContact O-N 2.96Å; N273-I276 PolarHBondContact O-N 2.78Å; N273-E277 PolarHBondContact ND2-OE1 3.19Å; N273-E277 WeakPolarHBondContact O-CG 3.42Å; N273-E277 PolarHBondContact O-N 3.4Å
274L78.1Confident75.1Confident43 Ų4367 Ų6723%0.22532%0.318CS..Hα-helixtrans-59.5-45.1171.9176.969.7000111.3T136 D270 F271 M272 I276 E277 L278T136-L274 HydrophobicContact CG2-CD2 4.35Å; T136-L274 WeakPolarHBondContact OG1-CD2 3.07Å; D270-L274 PolarHBondContact O-N 3.01Å; F271-L274 HydrophobicContact CD2-CD2 4.33Å; F271-L274 HydrophobicContact CE2-CD2 4.5Å; F271-L274 WeakPolarHBondContact O-CB 3.28Å; F271-L274 PolarHBondContact O-N 3.46Å; M272-L274 VanDerWaalsContact C-N 3.34Å; M272-L274 PolarHBondContact O-N 3.18Å; L274-I276 VanDerWaalsContact C-N 3.33Å; L274-I276 PolarHBondContact O-N 3.45Å; L274-E277 PolarHBondContact O-N 3.24Å; L274-L278 HydrophobicContact CD1-CD1 4.46Å; L274-L278 HydrophobicContact CD1-CG 4.45Å; L274-L278 HydrophobicContact CG-CD1 4.12Å; L274-L278 WeakPolarHBondContact O-CB 3.34Å; L274-L278 VanDerWaalsContact O-CG 3.25Å; L274-L278 WeakPolarHBondContact O-CG 3.25Å; L274-L278 PolarHBondContact O-N 3.33Å
275L81.5Confident74.2Confident0 Ų066.1 Ų66.10%032%0.321CS..Hα-helixtrans-64.3-39.2178.7-63.4179000112.1L133 F271 M272 N273 L278 K279 M295 L300 Q303 V304L133-L275 HydrophobicContact CD2-CD2 3.89Å; F271-L275 HydrophobicContact CD1-CD1 4.03Å; F271-L275 HydrophobicContact CD1-CG 4.44Å; F271-L275 HydrophobicContact CE1-CD1 3.58Å; F271-L275 HydrophobicContact CE1-CD2 4.31Å; F271-L275 HydrophobicContact CE1-CG 4.09Å; F271-L275 HydrophobicContact CE2-CD2 4Å; F271-L275 HydrophobicContact CE2-CG 4.21Å; F271-L275 HydrophobicContact CZ-CD1 3.9Å; F271-L275 HydrophobicContact CZ-CD2 3.74Å; F271-L275 HydrophobicContact CZ-CG 3.96Å; F271-L275 WeakPolarHBondContact O-CG 3.24Å; F271-L275 PolarHBondContact O-N 3.48Å; M272-L275 PolarHBondContact O-N 3.29Å; M272-L275 VanDerWaalsContact O-N 3.16Å; N273-L275 VanDerWaalsContact C-N 3.32Å; N273-L275 PolarHBondContact O-N 2.96Å; L275-L278 PolarHBondContact O-N 3.09Å; L275-K279 PolarHBondContact O-N 2.74Å; L275-M295 HydrophobicContact CB-CE 4.08Å; L275-M295 HydrophobicContact CD2-CE 3.53Å; L275-M295 HydrophobicContact CD2-SD 4.33Å; L275-M295 HydrophobicContact CG-CE 4.41Å; L275-L300 HydrophobicContact CB-CD1 3.7Å; L275-L300 HydrophobicContact CB-CD2 4.29Å; L275-L300 HydrophobicContact CB-CG 3.76Å; L275-L300 HydrophobicContact CD1-CD2 4.13Å; L275-L300 HydrophobicContact CD1-CG 4.06Å; L275-L300 HydrophobicContact CG-CG 4.48Å; L275-Q303 HydrophobicContact CD1-CB 4.29Å; L275-Q303 HydrophobicContact CD2-CB 4.3Å; L275-V304 HydrophobicContact CD1-CG2 3.6Å
276I81.3Confident73.6Confident11 Ų1160.8 Ų60.86%0.05629%0.292CS..Hα-helixtrans-63.1-45.4174.8-69.4167.7000110.7I258 M272 N273 L274 L278 K279 Q280I258-I276 HydrophobicContact CG1-CD1 4.12Å; I258-I276 HydrophobicContact CG1-CG1 4.02Å; M272-I276 HydrophobicContact CG-CD1 3.92Å; M272-I276 HydrophobicContact CG-CG1 4.46Å; M272-I276 VanDerWaalsContact O-CG1 3.29Å; M272-I276 WeakPolarHBondContact O-CG1 3.34Å; M272-I276 PolarHBondContact O-N 3.49Å; N273-I276 PolarHBondContact O-N 2.78Å; L274-I276 VanDerWaalsContact C-N 3.33Å; L274-I276 PolarHBondContact O-N 3.45Å; I276-L278 VanDerWaalsContact C-N 3.33Å; I276-L278 PolarHBondContact O-N 2.96Å; I276-K279 WeakPolarHBondContact O-CB 3.28Å; I276-K279 PolarHBondContact O-N 3.33Å; I276-K279 VanDerWaalsContact O-N 3.15Å; I276-Q280 HydrophobicContact CG2-CG 4.28Å; I276-Q280 WeakPolarHBondContact O-CB 3.47Å; I276-Q280 WeakPolarHBondContact O-CG 3.43Å; I276-Q280 PolarHBondContact O-N 2.93Å
277E78.9Confident72.7Confident55 Ų5565.3 Ų65.326%0.25732%0.321SS..Hα-helixtrans-62.2-40.6176.6-75.4179.5-167.200111.9N273 L274 K279 Q280 K281N273-E277 PolarHBondContact ND2-OE1 3.19Å; N273-E277 WeakPolarHBondContact O-CG 3.42Å; N273-E277 PolarHBondContact O-N 3.4Å; L274-E277 PolarHBondContact O-N 3.24Å; E277-K279 VanDerWaalsContact C-N 3.31Å; E277-K279 PolarHBondContact O-N 2.87Å; E277-Q280 PolarHBondContact O-N 2.58Å; E277-K281 WeakPolarHBondContact O-CB 3.46Å; E277-K281 VanDerWaalsContact O-CG 3.27Å; E277-K281 WeakPolarHBondContact O-CG 3.38Å; E277-K281 PolarHBondContact O-N 2.96Å
278L75.5Confident72.4Confident13 Ų1362.6 Ų62.67%0.06831%0.313CS..Hα-helixtrans-65-34.2174.9-71.4172.5000112.1R132 L274 L275 I276 V284 G294 M295R132-L278 HydrophobicContact CB-CD1 4.14Å; L274-L278 HydrophobicContact CD1-CD1 4.46Å; L274-L278 HydrophobicContact CD1-CG 4.45Å; L274-L278 HydrophobicContact CG-CD1 4.12Å; L274-L278 WeakPolarHBondContact O-CB 3.34Å; L274-L278 VanDerWaalsContact O-CG 3.25Å; L274-L278 WeakPolarHBondContact O-CG 3.25Å; L274-L278 PolarHBondContact O-N 3.33Å; L275-L278 PolarHBondContact O-N 3.09Å; I276-L278 VanDerWaalsContact C-N 3.33Å; I276-L278 PolarHBondContact O-N 2.96Å; L278-V284 HydrophobicContact CD2-CG2 3.8Å; L278-G294 VanDerWaalsContact O-CA 3.32Å; L278-G294 WeakPolarHBondContact O-CA 3.46Å; L278-M295 HydrophobicContact CB-CE 3.53Å; L278-M295 HydrophobicContact CD1-CE 3.77Å; L278-M295 HydrophobicContact CG-CE 4.32Å
279K75.7Confident72.1Confident77 Ų7761.2 Ų61.234%0.33533%0.325SS..Hα-helixtrans-67.7-45.7171.4173.8176.2-176.9-63.30111.6L275 I276 E277 M295 L300L275-K279 PolarHBondContact O-N 2.74Å; I276-K279 WeakPolarHBondContact O-CB 3.28Å; I276-K279 PolarHBondContact O-N 3.33Å; I276-K279 VanDerWaalsContact O-N 3.15Å; E277-K279 VanDerWaalsContact C-N 3.31Å; E277-K279 PolarHBondContact O-N 2.87Å; K279-M295 WeakPolarHBondContact CG-O 3.48Å; K279-L300 HydrophobicContact CB-CD1 4.33Å; K279-L300 HydrophobicContact CD-CD1 4.34Å
280Q73.6Confident72Confident116 Ų11659.5 Ų59.554%0.54231%0.313SS..Hα-helixtrans-71.6-36.9-175.6-74.3175.9-9.300113.6I276 E277 G282I276-Q280 HydrophobicContact CG2-CG 4.28Å; I276-Q280 WeakPolarHBondContact O-CB 3.47Å; I276-Q280 WeakPolarHBondContact O-CG 3.43Å; I276-Q280 PolarHBondContact O-N 2.93Å; E277-Q280 PolarHBondContact O-N 2.58Å; Q280-G282 PolarHBondContact O-N 3.39Å; Q280-G282 VanDerWaalsContact O-N 3.15Å
281K66.3Low71.5Confident128 Ų12862.8 Ų62.856%0.55733%0.333SS*.THydrogen-bonded Turntrans-62.1-23.9-178.1-77.9174.3-176.9174.80112.4E277 R283 V284E277-K281 WeakPolarHBondContact O-CB 3.46Å; E277-K281 VanDerWaalsContact O-CG 3.27Å; E277-K281 WeakPolarHBondContact O-CG 3.38Å; E277-K281 PolarHBondContact O-N 2.96Å; K281-R283 PolarHBondContact O-N 3.46Å; K281-V284 HydrophobicContact CB-CG2 4.11Å; K281-V284 HydrophobicContact CD-CG2 4.42Å
282G60.4Low70.9Confident40 Ų4062.6 Ų62.641%0.41233%0.333SS..SBendtrans66.8-33.917600000114.5Q280 E293 G294Q280-G282 PolarHBondContact O-N 3.39Å; Q280-G282 VanDerWaalsContact O-N 3.15Å; G282-E293 CarbonylContact O-C 3.43Å; G282-E293 WeakPolarHBondContact O-CA 3.2Å; G282-G294 PolarHBondContact O-N 2.73Å
283R63.9Low70.2Confident175 Ų17569.2 Ų69.266%0.6636%0.364SS*.EExtended strand (participates in β ladder)trans-142.5132.7169-71.7-178.1179.2155.21.1109K281 V291 I292K281-R283 PolarHBondContact O-N 3.46Å; R283-V291 HydrophobicContact CB-CG1 3.72Å; R283-V291 HydrophobicContact CG-CG1 3.99Å; R283-I292 CarbonylContact C-O 3.59Å; R283-I292 WeakPolarHBondContact CA-O 3.31Å
284V64.9Low69.5Low26 Ų2669.5 Ų69.516%0.15837%0.37CS..EExtended strand (participates in β ladder)trans-117118176.8179.20000107.7L278 K281 I292L278-V284 HydrophobicContact CD2-CG2 3.8Å; K281-V284 HydrophobicContact CB-CG2 4.11Å; K281-V284 HydrophobicContact CD-CG2 4.42Å; V284-I292 PolarHBondContact N-O 2.73Å; V284-I292 PolarHBondContact O-N 2.97Å
285T67.9Low69.5Low95 Ų9567.9 Ų67.958%0.58336%0.361SS*.EExtended strand (participates in β ladder)trans-82.1119169.4-50.10000108.1E290T285-E290 WeakPolarHBondContact CA-O 3.28Å
286L64.6Low69.7Low29 Ų2972.1 Ų72.115%0.15238%0.384CS..  trans-74.6163.8173.8-68.7-170.5000111.4Q131 N288 G289 E290 I292Q131-L286 HydrophobicContact CB-CD1 4.08Å; Q131-L286 HydrophobicContact CG-CD1 4.36Å; Q131-L286 VanDerWaalsContact OE1-CD1 3.25Å; L286-N288 WeakPolarHBondContact CB-OD1 3.33Å; L286-N288 PolarHBondContact O-N 2.89Å; L286-G289 PolarHBondContact O-N 3.22Å; L286-E290 HydrophobicContact CD1-CB 4.43Å; L286-E290 PolarHBondContact N-O 2.77Å; L286-I292 HydrophobicContact CD1-CD1 3.32Å; L286-I292 HydrophobicContact CD1-CG1 4.27Å; L286-I292 HydrophobicContact CD2-CD1 4Å; L286-I292 HydrophobicContact CG-CD1 3.57Å; L286-I292 HydrophobicContact CG-CG1 4.21Å
287D57.1Low70Confident183 Ų18374.1 Ų74.198%0.97939%0.394SS*.THydrogen-bonded Turntrans-58.7-20.6177-59.3-26.5000113.3G289D287-G289 VanDerWaalsContact C-N 3.35Å
288N64.4Low70.5Confident92 Ų9271.8 Ų71.849%0.49239%0.385SS..THydrogen-bonded Turntrans-89.56.2175.170.1-8000113.8L286 E290L286-N288 WeakPolarHBondContact CB-OD1 3.33Å; L286-N288 PolarHBondContact O-N 2.89Å; N288-E290 VanDerWaalsContact C-N 3.32Å; N288-E290 PolarHBondContact ND2-OE2 3.22Å; N288-E290 PolarHBondContact O-N 2.75Å; N288-E290 WeakPolarHBondContact OD1-CB 3.43Å; N288-E290 PolarHBondContact OD1-N 3.18Å
289G66Low71.2Confident53 Ų5372.7 Ų72.755%0.54639%0.389SS..SBendtrans81.8-2.7-178.500000115.5L286 D287L286-G289 PolarHBondContact O-N 3.22Å; D287-G289 VanDerWaalsContact C-N 3.35Å
290E67.6Low71.9Confident75 Ų7569 Ų6935%0.3537%0.373SS..  trans-72.4130.5177.1-72.1-179.4139.700111.1T285 L286 N288T285-E290 WeakPolarHBondContact CA-O 3.28Å; L286-E290 HydrophobicContact CD1-CB 4.43Å; L286-E290 PolarHBondContact N-O 2.77Å; N288-E290 VanDerWaalsContact C-N 3.32Å; N288-E290 PolarHBondContact ND2-OE2 3.22Å; N288-E290 PolarHBondContact O-N 2.75Å; N288-E290 WeakPolarHBondContact OD1-CB 3.43Å; N288-E290 PolarHBondContact OD1-N 3.18Å
291V69.1Low72.8Confident86 Ų8663.5 Ų63.552%0.52135%0.347SS..EExtended strand (participates in β ladder)trans-93.7124.8175.2-176.90000109.7R283R283-V291 HydrophobicContact CB-CG1 3.72Å; R283-V291 HydrophobicContact CG-CG1 3.99Å
292I66.6Low74.2Confident4 Ų457.4 Ų57.42%0.02132%0.32CS..EExtended strand (participates in β ladder)trans-119.2132.5-176.7-59.9-176.9000110.1D128 R283 V284 L286D128-I292 HydrophobicContact CB-CD1 4.16Å; D128-I292 HydrophobicContact CB-CG2 4.22Å; R283-I292 CarbonylContact C-O 3.59Å; R283-I292 WeakPolarHBondContact CA-O 3.31Å; V284-I292 PolarHBondContact N-O 2.73Å; V284-I292 PolarHBondContact O-N 2.97Å; L286-I292 HydrophobicContact CD1-CD1 3.32Å; L286-I292 HydrophobicContact CD1-CG1 4.27Å; L286-I292 HydrophobicContact CD2-CD1 4Å; L286-I292 HydrophobicContact CG-CD1 3.57Å; L286-I292 HydrophobicContact CG-CG1 4.21Å
293E67.7Low75.8Confident140 Ų14055.5 Ų55.565%0.65430%0.301SS*.EExtended strand (participates in β ladder)trans-63.9151.7177.3-64.6-175.2160.300113.1R132 G282R132-E293 PolarHBondContact NH1-O 3.29Å; R132-E293 PolarHBondContact NH2-O 3.34Å; G282-E293 CarbonylContact O-C 3.43Å; G282-E293 WeakPolarHBondContact O-CA 3.2Å
294G68.4Low77.1Confident19 Ų1947.1 Ų47.120%0.19627%0.269CS..PPolyproline II helixtrans-64172.1176.700000113.1L278 G282L278-G294 VanDerWaalsContact O-CA 3.32Å; L278-G294 WeakPolarHBondContact O-CA 3.46Å; G282-G294 PolarHBondContact O-N 2.73Å
295M78.6Confident78.4Confident8 Ų846.2 Ų46.24%0.03926%0.263CS..PPolyproline II helixtrans-91141.5178.4-73.2-177.8-61.300112.5M129 L275 L278 K279 E299 Q303M129-M295 HydrophobicContact CE-CG 4.33Å; M129-M295 HydrophobicContact CE-SD 3.84Å; M129-M295 HydrophobicContact SD-SD 4.03Å; L275-M295 HydrophobicContact CB-CE 4.08Å; L275-M295 HydrophobicContact CD2-CE 3.53Å; L275-M295 HydrophobicContact CD2-SD 4.33Å; L275-M295 HydrophobicContact CG-CE 4.41Å; L278-M295 HydrophobicContact CB-CE 3.53Å; L278-M295 HydrophobicContact CD1-CE 3.77Å; L278-M295 HydrophobicContact CG-CE 4.32Å; K279-M295 WeakPolarHBondContact CG-O 3.48Å; M295-E299 WeakPolarHBondContact CA-OE2 3.45Å; M295-E299 HydrophobicContact CB-CB 4.25Å; M295-E299 HydrophobicContact CG-CB 4.38Å; M295-Q303 HydrophobicContact SD-CG 4.44Å
296D84.9Confident79.6Confident89 Ų8942.7 Ų42.748%0.47624%0.242SC..PPolyproline II helixtrans-78.5170.9164.478.142.7000112G298 E299 L300D296-G298 VanDerWaalsContact C-N 3.3Å; D296-G298 PolarHBondContact O-N 3.35Å; D296-G298 VanDerWaalsContact OD1-CA 3.26Å; D296-G298 WeakPolarHBondContact OD1-CA 3.41Å; D296-G298 PolarHBondContact OD1-N 3.25Å; D296-E299 PolarHBondContact N-OE2 3.18Å; D296-E299 VanDerWaalsContact N-OE2 3.11Å; D296-E299 PolarHBondContact O-N 3.31Å; D296-E299 PolarHBondContact OD1-N 3.4Å; D296-L300 WeakPolarHBondContact O-CB 3.47Å; D296-L300 PolarHBondContact O-N 2.58Å
297I87.4Confident81Confident53 Ų5342.2 Ų42.227%0.27224%0.238SC..Hα-helixtrans-64.5-34.2-177.9-168.364.4000112.8V254 N255 I258 A301V254-I297 HydrophobicContact CG1-CD1 3.71Å; N255-I297 WeakPolarHBondContact OD1-CG1 3.49Å; I258-I297 HydrophobicContact CD1-CD1 3.47Å; I258-I297 VanDerWaalsContact CD1-CD1 3.47Å; I297-A301 WeakPolarHBondContact O-CB 3.47Å; I297-A301 PolarHBondContact O-N 2.86Å
298G90.5Very high82.6Confident7 Ų733.5 Ų33.57%0.07219%0.192CC..Hα-helixtrans-71-42.5178.300000111.5D296 L300 A301 A302D296-G298 VanDerWaalsContact C-N 3.3Å; D296-G298 PolarHBondContact O-N 3.35Å; D296-G298 VanDerWaalsContact OD1-CA 3.26Å; D296-G298 WeakPolarHBondContact OD1-CA 3.41Å; D296-G298 PolarHBondContact OD1-N 3.25Å; G298-L300 VanDerWaalsContact C-N 3.33Å; G298-A301 PolarHBondContact O-N 3.07Å; G298-A302 WeakPolarHBondContact O-CB 3.4Å; G298-A302 PolarHBondContact O-N 3.38Å
299E90.3Very high83.9Confident31 Ų3129.9 Ų29.915%0.14517%0.173CC..Hα-helixtrans-62.3-41.2173.6-70-177.7139.200111.6M295 D296 A302 Q303M295-E299 WeakPolarHBondContact CA-OE2 3.45Å; M295-E299 HydrophobicContact CB-CB 4.25Å; M295-E299 HydrophobicContact CG-CB 4.38Å; D296-E299 PolarHBondContact N-OE2 3.18Å; D296-E299 VanDerWaalsContact N-OE2 3.11Å; D296-E299 PolarHBondContact O-N 3.31Å; D296-E299 PolarHBondContact OD1-N 3.4Å; E299-A302 PolarHBondContact O-N 2.99Å; E299-Q303 WeakPolarHBondContact O-CG 3.35Å; E299-Q303 PolarHBondContact O-N 3.06Å; E299-Q303 VanDerWaalsContact O-N 3.07Å; E299-Q303 PolarHBondContact O-NE2 2.69Å
300L90.4Very high85.1Confident0 Ų029.7 Ų29.70%017%0.166CC..Hα-helixtrans-63.3-48.9175.8-164.5150.9000110.7V254 I258 M272 L275 K279 D296 G298 A302 Q303 V304V254-L300 HydrophobicContact CB-CD2 4.48Å; V254-L300 HydrophobicContact CG1-CD2 3.34Å; V254-L300 HydrophobicContact CG2-CD2 4.37Å; I258-L300 HydrophobicContact CD1-CD1 4.17Å; I258-L300 HydrophobicContact CD1-CD2 4.32Å; M272-L300 HydrophobicContact SD-CD2 3.89Å; L275-L300 HydrophobicContact CB-CD1 3.7Å; L275-L300 HydrophobicContact CB-CD2 4.29Å; L275-L300 HydrophobicContact CB-CG 3.76Å; L275-L300 HydrophobicContact CD1-CD2 4.13Å; L275-L300 HydrophobicContact CD1-CG 4.06Å; L275-L300 HydrophobicContact CG-CG 4.48Å; K279-L300 HydrophobicContact CB-CD1 4.33Å; K279-L300 HydrophobicContact CD-CD1 4.34Å; D296-L300 WeakPolarHBondContact O-CB 3.47Å; D296-L300 PolarHBondContact O-N 2.58Å; G298-L300 VanDerWaalsContact C-N 3.33Å; L300-A302 VanDerWaalsContact C-N 3.29Å; L300-A302 PolarHBondContact O-N 3.3Å; L300-Q303 PolarHBondContact O-N 3.25Å; L300-Q303 VanDerWaalsContact O-N 3.16Å; L300-V304 HydrophobicContact CD2-CG2 3.96Å; L300-V304 WeakPolarHBondContact O-CG2 3.38Å; L300-V304 PolarHBondContact O-N 3.27Å
301A92.6Very high86.1Confident0 Ų026.5 Ų26.50%015%0.153CC..Hα-helixtrans-62.2-37177.600000112.6L114 M251 V254 I297 G298 Q303 V304 F305L114-A301 HydrophobicContact CD2-CB 3.8Å; M251-A301 HydrophobicContact CE-CB 4.46Å; M251-A301 HydrophobicContact SD-CB 3.52Å; M251-A301 VanDerWaalsContact SD-CB 3.52Å; V254-A301 HydrophobicContact CB-CB 4.23Å; V254-A301 HydrophobicContact CG1-CB 4.32Å; V254-A301 HydrophobicContact CG2-CB 3.95Å; I297-A301 WeakPolarHBondContact O-CB 3.47Å; I297-A301 PolarHBondContact O-N 2.86Å; G298-A301 PolarHBondContact O-N 3.07Å; A301-Q303 PolarHBondContact O-N 2.89Å; A301-V304 PolarHBondContact O-N 3.32Å; A301-F305 VanDerWaalsContact O-CB 3.24Å; A301-F305 WeakPolarHBondContact O-CB 3.47Å; A301-F305 PolarHBondContact O-N 2.71Å
302A94.5Very high87Confident0 Ų022.4 Ų22.40%013%0.128CC..Hα-helixtrans-61.9-41.7174.200000112.1P113 H117 G298 E299 L300 V306P113-A302 WeakPolarHBondContact O-CB 3.26Å; H117-A302 HydrophobicContact CB-CB 4.05Å; H117-A302 VanDerWaalsContact CB-O 3.25Å; H117-A302 WeakPolarHBondContact CB-O 3.4Å; G298-A302 WeakPolarHBondContact O-CB 3.4Å; G298-A302 PolarHBondContact O-N 3.38Å; E299-A302 PolarHBondContact O-N 2.99Å; L300-A302 VanDerWaalsContact C-N 3.29Å; L300-A302 PolarHBondContact O-N 3.3Å; A302-V306 PolarHBondContact O-N 2.88Å
303Q93.6Very high88.1Confident0 Ų023 Ų230%013%0.131CC..Hα-helixtrans-67.3-47.4176-58.3-23.4-68.700110.8Q116 M129 L133 F271 L275 M295 E299 L300 A301 F305 V306 F307Q116-Q303 PolarHBondContact O-NE2 3.37Å; M129-Q303 HydrophobicContact CE-CG 4.29Å; M129-Q303 HydrophobicContact SD-CG 3.89Å; L133-Q303 HydrophobicContact CD1-CG 4.4Å; F271-Q303 HydrophobicContact CZ-CB 4.5Å; L275-Q303 HydrophobicContact CD1-CB 4.29Å; L275-Q303 HydrophobicContact CD2-CB 4.3Å; M295-Q303 HydrophobicContact SD-CG 4.44Å; E299-Q303 WeakPolarHBondContact O-CG 3.35Å; E299-Q303 PolarHBondContact O-N 3.06Å; E299-Q303 VanDerWaalsContact O-N 3.07Å; E299-Q303 PolarHBondContact O-NE2 2.69Å; L300-Q303 PolarHBondContact O-N 3.25Å; L300-Q303 VanDerWaalsContact O-N 3.16Å; A301-Q303 PolarHBondContact O-N 2.89Å; Q303-F305 VanDerWaalsContact C-N 3.28Å; Q303-F305 PolarHBondContact O-N 3.01Å; Q303-V306 WeakPolarHBondContact O-CG1 3.43Å; Q303-V306 PolarHBondContact O-N 3.2Å; Q303-F307 HydrophobicContact CB-CD2 4.32Å; Q303-F307 HydrophobicContact CB-CE2 4.42Å; Q303-F307 WeakPolarHBondContact O-CD2 3.03Å; Q303-F307 PolarHBondContact O-N 2.87Å
304V91.4Very high89.4Confident0 Ų018.6 Ų18.60%011%0.114CC..Hα-helixtrans-54.1-47.5176.81660000111.1F192 F250 V254 M272 L275 L300 A301 Y308F192-V304 HydrophobicContact CD1-CG1 3.94Å; F192-V304 HydrophobicContact CD1-CG2 4.35Å; F192-V304 HydrophobicContact CE1-CB 4.03Å; F192-V304 HydrophobicContact CE1-CG1 3.58Å; F192-V304 HydrophobicContact CE1-CG2 4.04Å; F192-V304 HydrophobicContact CZ-CG1 4.08Å; F192-V304 WeakPolarHBondContact CZ-O 3.34Å; F250-V304 HydrophobicContact CD1-CG1 4.39Å; V254-V304 HydrophobicContact CG2-CB 3.95Å; V254-V304 HydrophobicContact CG2-CG1 3.86Å; V254-V304 HydrophobicContact CG2-CG2 4.03Å; M272-V304 HydrophobicContact CE-CG1 4.41Å; M272-V304 HydrophobicContact CE-CG2 3.74Å; M272-V304 HydrophobicContact SD-CG2 4.19Å; L275-V304 HydrophobicContact CD1-CG2 3.6Å; L300-V304 HydrophobicContact CD2-CG2 3.96Å; L300-V304 WeakPolarHBondContact O-CG2 3.38Å; L300-V304 PolarHBondContact O-N 3.27Å; A301-V304 PolarHBondContact O-N 3.32Å; V304-Y308 WeakPolarHBondContact O-CB 3.32Å; V304-Y308 PolarHBondContact O-N 3.14Å
305F93.3Very high90.7Very high6 Ų618 Ų183%0.02611%0.106CC..Hα-helixtrans-56.4-54.1176169.4-104.8000112.5L114 H117 V213 M242 V246 F250 A301 Q303 F307 Y308 V309L114-F305 HydrophobicContact CB-CD1 4.21Å; L114-F305 HydrophobicContact CB-CG 4.38Å; L114-F305 HydrophobicContact CD1-CB 4.46Å; L114-F305 HydrophobicContact CD1-CD2 4.14Å; L114-F305 HydrophobicContact CD1-CG 4.19Å; L114-F305 HydrophobicContact CD2-CB 4.07Å; H117-F305 AromaticContact CD2-CD1 3.93Å; V213-F305 HydrophobicContact CG1-CE2 4.34Å; V213-F305 HydrophobicContact CG1-CZ 3.86Å; V213-F305 HydrophobicContact CG2-CE2 3.56Å; V213-F305 HydrophobicContact CG2-CZ 3.92Å; M242-F305 HydrophobicContact SD-CE1 3.81Å; M242-F305 HydrophobicContact SD-CE2 4.23Å; M242-F305 HydrophobicContact SD-CZ 3.43Å; M242-F305 WeakPolarHBondContact SD-CZ 3.42Å; V246-F305 HydrophobicContact CG1-CE2 3.91Å; F250-F305 HydrophobicContact CD1-CB 4.25Å; F250-F305 HydrophobicContact CD1-CD2 4.36Å; F250-F305 AromaticContact CD2-CD2 3.53Å; F250-F305 HydrophobicContact CD2-CD2 3.53Å; F250-F305 HydrophobicContact CD2-CE2 4.18Å; F250-F305 HydrophobicContact CE1-CD2 4.4Å; F250-F305 AromaticContact CE2-CD2 3.6Å; F250-F305 HydrophobicContact CE2-CD2 3.6Å; F250-F305 HydrophobicContact CE2-CE2 4.03Å; F250-F305 HydrophobicContact CG-CB 4.22Å; F250-F305 AromaticContact CG-CD2 3.96Å; F250-F305 HydrophobicContact CG-CD2 3.96Å; F250-F305 HydrophobicContact CZ-CD2 4.06Å; A301-F305 VanDerWaalsContact O-CB 3.24Å; A301-F305 WeakPolarHBondContact O-CB 3.47Å; A301-F305 PolarHBondContact O-N 2.71Å; Q303-F305 VanDerWaalsContact C-N 3.28Å; Q303-F305 PolarHBondContact O-N 3.01Å; F305-F307 PolarHBondContact O-N 3.37Å; F305-Y308 PolarHBondContact O-N 2.94Å; F305-V309 HydrophobicContact CD2-CG2 4.09Å; F305-V309 HydrophobicContact CE2-CG2 3.75Å; F305-V309 HydrophobicContact CZ-CG2 4.04Å; F305-V309 WeakPolarHBondContact O-CG2 3.4Å; F305-V309 PolarHBondContact O-N 2.81Å
306V93.3Very high91.5Very high22 Ų2217.6 Ų17.613%0.13311%0.105CC..Hα-helixtrans-67.1-36.2-175.378.80000112.5H117 F119 A302 Q303 A310H117-V306 HydrophobicContact CB-CB 3.63Å; H117-V306 HydrophobicContact CB-CG1 3.71Å; H117-V306 HydrophobicContact CB-CG2 4.21Å; F119-V306 HydrophobicContact CB-CG2 4.2Å; A302-V306 PolarHBondContact O-N 2.88Å; Q303-V306 WeakPolarHBondContact O-CG1 3.43Å; Q303-V306 PolarHBondContact O-N 3.2Å; V306-A310 WeakPolarHBondContact O-CB 3.46Å; V306-A310 PolarHBondContact O-N 3.06Å
307F92.7Very high92Very high19 Ų1913.4 Ų13.48%0.0838%0.083CC..Hα-helixtrans-72.4-34.2179.3-80.8-72.2000112.2L118 L133 F137 F271 Q303 F305 G311 I452L118-F307 HydrophobicContact CD2-CZ 4.5Å; L133-F307 HydrophobicContact CD1-CE2 3.79Å; L133-F307 HydrophobicContact CD1-CZ 4.02Å; L133-F307 HydrophobicContact CD2-CE2 4.26Å; F137-F307 HydrophobicContact CE1-CE1 4.25Å; F137-F307 HydrophobicContact CE2-CD1 4.3Å; F137-F307 AromaticContact CE2-CE1 3.4Å; F137-F307 HydrophobicContact CE2-CE1 3.4Å; F137-F307 AromaticContact CE2-CZ 3.7Å; F137-F307 HydrophobicContact CE2-CZ 3.7Å; F137-F307 AromaticContact CZ-CD1 3.67Å; F137-F307 HydrophobicContact CZ-CD1 3.67Å; F137-F307 AromaticContact CZ-CE1 3.17Å; F137-F307 HydrophobicContact CZ-CE1 3.17Å; F137-F307 AromaticContact CZ-CZ 3.93Å; F137-F307 HydrophobicContact CZ-CZ 3.93Å; F271-F307 HydrophobicContact CD1-CD2 4.45Å; F271-F307 HydrophobicContact CE1-CB 4.08Å; F271-F307 AromaticContact CE1-CD2 3.33Å; F271-F307 HydrophobicContact CE1-CD2 3.33Å; F271-F307 AromaticContact CE1-CE2 3.95Å; F271-F307 HydrophobicContact CE1-CE2 3.95Å; F271-F307 AromaticContact CE1-CG 3.81Å; F271-F307 HydrophobicContact CE1-CG 3.81Å; F271-F307 HydrophobicContact CE2-CD2 4.36Å; F271-F307 HydrophobicContact CE2-CE2 4.2Å; F271-F307 AromaticContact CZ-CD2 3.27Å; F271-F307 HydrophobicContact CZ-CD2 3.27Å; F271-F307 AromaticContact CZ-CE2 3.36Å; F271-F307 HydrophobicContact CZ-CE2 3.36Å; F271-F307 HydrophobicContact CZ-CG 4.03Å; F271-F307 HydrophobicContact CZ-CZ 4.14Å; Q303-F307 HydrophobicContact CB-CD2 4.32Å; Q303-F307 HydrophobicContact CB-CE2 4.42Å; Q303-F307 WeakPolarHBondContact O-CD2 3.03Å; Q303-F307 PolarHBondContact O-N 2.87Å; F305-F307 PolarHBondContact O-N 3.37Å; F307-G311 WeakPolarHBondContact O-CA 3.5Å; F307-G311 PolarHBondContact O-N 3.21Å; F307-I452 HydrophobicContact CE1-CG2 3.63Å; F307-I452 HydrophobicContact CZ-CG2 3.89Å
308Y91.7Very high92.5Very high0 Ų011.5 Ų11.50%07%0.073CC..Hα-helixtrans-60.1-59.2170.3176.3-105.3000110.1T184 I187 F192 F206 F250 V304 F305 A310 G311 F312T184-Y308 HydrophobicContact CG2-CE2 4.13Å; I187-Y308 HydrophobicContact CG2-CD2 3.8Å; I187-Y308 HydrophobicContact CG2-CE2 4.08Å; F192-Y308 AromaticContact CE2-CD2 3.92Å; F192-Y308 HydrophobicContact CE2-CD2 3.92Å; F192-Y308 HydrophobicContact CE2-CG 4.3Å; F206-Y308 HydrophobicContact CD1-CD2 4.32Å; F206-Y308 AromaticContact CD1-CE2 3.82Å; F206-Y308 HydrophobicContact CD1-CE2 3.82Å; F206-Y308 PolarHBondContact O-OH 2.77Å; F250-Y308 AromaticContact CE1-CD1 3.8Å; F250-Y308 HydrophobicContact CE1-CD1 3.8Å; F250-Y308 HydrophobicContact CE1-CG 4.05Å; F250-Y308 AromaticContact CZ-CD1 3.41Å; F250-Y308 HydrophobicContact CZ-CD1 3.41Å; F250-Y308 VanDerWaalsContact CZ-CD1 3.41Å; F250-Y308 AromaticContact CZ-CE1 3.88Å; F250-Y308 HydrophobicContact CZ-CE1 3.88Å; F250-Y308 HydrophobicContact CZ-CG 4.14Å; V304-Y308 WeakPolarHBondContact O-CB 3.32Å; V304-Y308 PolarHBondContact O-N 3.14Å; F305-Y308 PolarHBondContact O-N 2.94Å; Y308-A310 PolarHBondContact O-N 2.95Å; Y308-G311 PolarHBondContact O-N 2.92Å; Y308-G311 VanDerWaalsContact O-N 3.12Å; Y308-F312 HydrophobicContact CD1-CD1 4Å; Y308-F312 AromaticContact CD1-CE1 3.96Å; Y308-F312 HydrophobicContact CD1-CE1 3.96Å; Y308-F312 AromaticContact CE1-CD1 3.7Å; Y308-F312 HydrophobicContact CE1-CD1 3.7Å; Y308-F312 AromaticContact CE1-CE1 3.55Å; Y308-F312 HydrophobicContact CE1-CE1 3.55Å; Y308-F312 HydrophobicContact CE2-CD1 4.21Å; Y308-F312 HydrophobicContact CG-CD1 4.41Å; Y308-F312 AromaticContact CZ-CD1 3.77Å; Y308-F312 WeakPolarHBondContact O-CD1 3.39Å; Y308-F312 PolarHBondContact O-N 3.19Å; Y308-F312 VanDerWaalsContact O-N 3.14Å
309V91.1Very high92.9Very high15 Ų1511.1 Ų11.19%0.0917%0.07CC..Hα-helixtrans-59.5-46.8-175.5173.60000112.3V213 F214 F305 G311 E313V213-V309 HydrophobicContact CB-CG2 4.38Å; V213-V309 HydrophobicContact CG1-CG1 4Å; V213-V309 HydrophobicContact CG1-CG2 4.15Å; V213-V309 HydrophobicContact CG2-CG2 3.98Å; F214-V309 HydrophobicContact CE1-CG1 4.2Å; F214-V309 HydrophobicContact CE2-CG1 3.59Å; F214-V309 HydrophobicContact CZ-CG1 3.28Å; F305-V309 HydrophobicContact CD2-CG2 4.09Å; F305-V309 HydrophobicContact CE2-CG2 3.75Å; F305-V309 HydrophobicContact CZ-CG2 4.04Å; F305-V309 WeakPolarHBondContact O-CG2 3.4Å; F305-V309 PolarHBondContact O-N 2.81Å; V309-G311 VanDerWaalsContact C-N 3.33Å; V309-G311 PolarHBondContact O-N 2.63Å; V309-E313 PolarHBondContact O-N 2.99Å
310A91.8Very high93.3Very high49 Ų499.7 Ų9.741%0.4056%0.063SC..Hα-helixtrans-67.8-34.6178.400000112.2V306 Y308 T314V306-A310 WeakPolarHBondContact O-CB 3.46Å; V306-A310 PolarHBondContact O-N 3.06Å; Y308-A310 PolarHBondContact O-N 2.95Å; A310-T314 PolarHBondContact O-OG1 3.02Å
311G88.2Confident93.7Very high8 Ų89.7 Ų9.78%0.0826%0.063CC..Hα-helixtrans-72.9-35.8-174.400000114.3F307 Y308 V309 S315 Q460F307-G311 WeakPolarHBondContact O-CA 3.5Å; F307-G311 PolarHBondContact O-N 3.21Å; Y308-G311 PolarHBondContact O-N 2.92Å; Y308-G311 VanDerWaalsContact O-N 3.12Å; V309-G311 VanDerWaalsContact C-N 3.33Å; V309-G311 PolarHBondContact O-N 2.63Å; G311-S315 PolarHBondContact O-OG 2.88Å; G311-Q460 PolarHBondContact O-NE2 2.9Å
312F87.7Confident94Very high0 Ų09.7 Ų9.70%06%0.063CC..Hα-helixtrans-88.8-57.7-178.287.7-99.7000112.7T183 I187 G210 F214 Y308 T314 S316T183-F312 PolarHBondContact OG1-O 3.14Å; I187-F312 HydrophobicContact CG2-CB 4.35Å; G210-F312 WeakPolarHBondContact O-CZ 3.5Å; F214-F312 HydrophobicContact CD2-CZ 4.33Å; F214-F312 HydrophobicContact CE2-CE1 4.39Å; F214-F312 HydrophobicContact CE2-CE2 4.47Å; F214-F312 AromaticContact CE2-CZ 3.78Å; F214-F312 HydrophobicContact CE2-CZ 3.78Å; Y308-F312 HydrophobicContact CD1-CD1 4Å; Y308-F312 AromaticContact CD1-CE1 3.96Å; Y308-F312 HydrophobicContact CD1-CE1 3.96Å; Y308-F312 AromaticContact CE1-CD1 3.7Å; Y308-F312 HydrophobicContact CE1-CD1 3.7Å; Y308-F312 AromaticContact CE1-CE1 3.55Å; Y308-F312 HydrophobicContact CE1-CE1 3.55Å; Y308-F312 HydrophobicContact CE2-CD1 4.21Å; Y308-F312 HydrophobicContact CG-CD1 4.41Å; Y308-F312 AromaticContact CZ-CD1 3.77Å; Y308-F312 WeakPolarHBondContact O-CD1 3.39Å; Y308-F312 PolarHBondContact O-N 3.19Å; Y308-F312 VanDerWaalsContact O-N 3.14Å; F312-T314 PolarHBondContact O-N 3.15Å; F312-S316 VanDerWaalsContact O-CB 3.29Å; F312-S316 WeakPolarHBondContact O-CB 3.43Å; F312-S316 PolarHBondContact O-N 3.22Å; F312-S316 PolarHBondContact O-OG 3.49Å
313E90.3Very high94.2Very high17 Ų179.7 Ų9.78%0.0796%0.063CC..Hα-helixtrans-68.6-37.2-165.8-174.763.5-165.400112.8F214 V309 S316 S317 V492F214-E313 HydrophobicContact CD2-CB 4.45Å; F214-E313 HydrophobicContact CD2-CG 4.15Å; F214-E313 HydrophobicContact CE1-CG 4.21Å; F214-E313 HydrophobicContact CE2-CB 3.56Å; F214-E313 HydrophobicContact CE2-CG 3.66Å; F214-E313 HydrophobicContact CZ-CB 3.6Å; F214-E313 HydrophobicContact CZ-CG 3.68Å; V309-E313 PolarHBondContact O-N 2.99Å; E313-S316 WeakPolarHBondContact CA-OG 3.4Å; E313-S316 PolarHBondContact O-OG 3.4Å; E313-S317 VanDerWaalsContact O-CB 3.3Å; E313-S317 WeakPolarHBondContact O-CB 3.21Å; E313-S317 PolarHBondContact O-N 3.07Å; E313-S317 VanDerWaalsContact O-N 3.13Å; E313-S317 PolarHBondContact O-OG 3.41Å; E313-V492 HydrophobicContact CG-CG2 4.4Å
314T93.9Very high94.4Very high47 Ų4710.1 Ų10.129%0.2886%0.064SC..Hα-helixtrans-73.7-44.7-177.365.40000111.9A310 F312 T318 L375A310-T314 PolarHBondContact O-OG1 3.02Å; F312-T314 PolarHBondContact O-N 3.15Å; T314-T318 WeakPolarHBondContact O-CB 3.33Å; T314-T318 PolarHBondContact O-N 3.44Å; T314-T318 PolarHBondContact O-OG1 3.47Å; T314-L375 HydrophobicContact CG2-CD1 4.41Å; T314-L375 WeakPolarHBondContact O-CD1 3.36Å
315S95.8Very high94.8Very high6 Ų611.1 Ų11.14%0.0427%0.069CC..Hα-helixtrans-67.2-41178.3-57.20000111.3G311 T318 M319 Q460G311-S315 PolarHBondContact O-OG 2.88Å; S315-T318 PolarHBondContact O-N 3.05Å; S315-M319 WeakPolarHBondContact O-CE 3.32Å; S315-M319 PolarHBondContact O-N 3.32Å; S315-Q460 PolarHBondContact OG-NE2 3.03Å
316S95.6Very high95Very high0 Ų010.9 Ų10.90%07%0.068CC..Hα-helixtrans-63.6-45.9178.864.20000111.6F312 E313 T318 M319 S320F312-S316 VanDerWaalsContact O-CB 3.29Å; F312-S316 WeakPolarHBondContact O-CB 3.43Å; F312-S316 PolarHBondContact O-N 3.22Å; F312-S316 PolarHBondContact O-OG 3.49Å; E313-S316 WeakPolarHBondContact CA-OG 3.4Å; E313-S316 PolarHBondContact O-OG 3.4Å; S316-T318 PolarHBondContact O-N 2.8Å; S316-M319 PolarHBondContact O-N 3.49Å; S316-S320 WeakPolarHBondContact O-CB 3.42Å; S316-S320 PolarHBondContact O-N 2.98Å; S316-S320 PolarHBondContact O-OG 2.93Å
317S96.1Very high95.3Very high2 Ų210 Ų101%0.0146%0.063CC..Hα-helixtrans-61.9-44.5176.8-62.10000111.4E313 M319 S320 Y321E313-S317 VanDerWaalsContact O-CB 3.3Å; E313-S317 WeakPolarHBondContact O-CB 3.21Å; E313-S317 PolarHBondContact O-N 3.07Å; E313-S317 VanDerWaalsContact O-N 3.13Å; E313-S317 PolarHBondContact O-OG 3.41Å; S317-M319 PolarHBondContact O-N 3.28Å; S317-S320 PolarHBondContact O-N 3.1Å; S317-Y321 WeakPolarHBondContact O-CD2 3.42Å; S317-Y321 PolarHBondContact O-N 3.47Å
318T98Very high95.5Very high12 Ų1212.3 Ų12.37%0.0748%0.075CC..Hα-helixtrans-57.8-49.9177.6-56.90000111.6T314 S315 S316 S320 Y321 C322 I366 L370 L375T314-T318 WeakPolarHBondContact O-CB 3.33Å; T314-T318 PolarHBondContact O-N 3.44Å; T314-T318 PolarHBondContact O-OG1 3.47Å; S315-T318 PolarHBondContact O-N 3.05Å; S316-T318 PolarHBondContact O-N 2.8Å; T318-S320 VanDerWaalsContact C-N 3.32Å; T318-S320 PolarHBondContact O-N 3.27Å; T318-Y321 PolarHBondContact O-N 2.95Å; T318-C322 WeakPolarHBondContact O-CB 3.37Å; T318-C322 PolarHBondContact O-N 2.91Å; T318-I366 HydrophobicContact CG2-CG2 4.47Å; T318-L370 HydrophobicContact CG2-CD2 3.72Å; T318-L370 HydrophobicContact CG2-CG 3.96Å; T318-L375 WeakPolarHBondContact OG1-CD1 3.45Å
319M98.6Very high95.8Very high0 Ų014.4 Ų14.40%09%0.085CC..Hα-helixtrans-65.9-36.8178.8-67.8-176-74.600111.9M179 F182 T183 S315 S316 S317 C322 L323 A461 L465M179-M319 HydrophobicContact CB-CE 4.4Å; M179-M319 HydrophobicContact CG-CB 3.97Å; M179-M319 HydrophobicContact SD-CB 3.39Å; M179-M319 WeakPolarHBondContact SD-CB 3.34Å; M179-M319 HydrophobicContact SD-CE 3.76Å; M179-M319 HydrophobicContact SD-CG 4.19Å; M179-M319 HydrophobicContact SD-SD 3.73Å; F182-M319 HydrophobicContact CD1-CE 3.77Å; F182-M319 HydrophobicContact CD1-SD 4.28Å; F182-M319 HydrophobicContact CE1-CE 4.1Å; F182-M319 HydrophobicContact CE1-SD 4.21Å; T183-M319 HydrophobicContact CG2-CE 3.23Å; S315-M319 WeakPolarHBondContact O-CE 3.32Å; S315-M319 PolarHBondContact O-N 3.32Å; S316-M319 PolarHBondContact O-N 3.49Å; S317-M319 PolarHBondContact O-N 3.28Å; M319-C322 WeakPolarHBondContact O-CB 3.46Å; M319-C322 PolarHBondContact O-N 3.49Å; M319-L323 VanDerWaalsContact O-CG 3.28Å; M319-L323 WeakPolarHBondContact O-CG 3.42Å; M319-L323 PolarHBondContact O-N 2.93Å; M319-A461 HydrophobicContact CG-CB 3.99Å; M319-A461 HydrophobicContact SD-CB 4.48Å; M319-L465 HydrophobicContact CB-CD2 4.2Å; M319-L465 HydrophobicContact CB-CG 4.36Å; M319-L465 HydrophobicContact CG-CD1 4.26Å; M319-L465 HydrophobicContact CG-CD2 4.37Å; M319-L465 HydrophobicContact CG-CG 3.98Å
320S98.4Very high96.2Very high0 Ų016 Ų160%09%0.092CC..Hα-helixtrans-65.3-43.6178.9-52.30000112K176 M179 S316 S317 T318 L323 Y324K176-S320 WeakPolarHBondContact CA-OG 3.36Å; M179-S320 WeakPolarHBondContact CG-OG 3.48Å; S316-S320 WeakPolarHBondContact O-CB 3.42Å; S316-S320 PolarHBondContact O-N 2.98Å; S316-S320 PolarHBondContact O-OG 2.93Å; S317-S320 PolarHBondContact O-N 3.1Å; T318-S320 VanDerWaalsContact C-N 3.32Å; T318-S320 PolarHBondContact O-N 3.27Å; S320-L323 PolarHBondContact O-N 3.26Å; S320-Y324 WeakPolarHBondContact O-CB 3.26Å; S320-Y324 PolarHBondContact O-N 3.41Å
321Y98.6Very high96.5Very high1 Ų119.1 Ų19.10%0.00410%0.102CC..Hα-helixtrans-67.2-38175.1-64.2-44.9000112.2S317 T318 Y324 E325 Y373 L375 L484 Y486 L493 T495 I499S317-Y321 WeakPolarHBondContact O-CD2 3.42Å; S317-Y321 PolarHBondContact O-N 3.47Å; T318-Y321 PolarHBondContact O-N 2.95Å; Y321-Y324 WeakPolarHBondContact O-CB 3.25Å; Y321-Y324 PolarHBondContact O-N 3.33Å; Y321-E325 PolarHBondContact O-N 3.32Å; Y321-Y373 AromaticContact CD1-CD1 3.58Å; Y321-Y373 HydrophobicContact CD1-CD1 3.58Å; Y321-Y373 AromaticContact CD1-CE1 3.68Å; Y321-Y373 HydrophobicContact CD1-CE1 3.68Å; Y321-Y373 HydrophobicContact CD1-CG 4.19Å; Y321-Y373 AromaticContact CD2-CD1 3.81Å; Y321-Y373 HydrophobicContact CD2-CD1 3.81Å; Y321-Y373 AromaticContact CD2-CG 3.79Å; Y321-Y373 HydrophobicContact CD2-CG 3.79Å; Y321-Y373 HydrophobicContact CE1-CD1 4Å; Y321-Y373 HydrophobicContact CE1-CE1 4.23Å; Y321-Y373 HydrophobicContact CE2-CD1 4.2Å; Y321-Y373 HydrophobicContact CE2-CG 4.5Å; Y321-Y373 AromaticContact CG-CD1 3.49Å; Y321-Y373 HydrophobicContact CG-CD1 3.49Å; Y321-Y373 VanDerWaalsContact CG-CD1 3.49Å; Y321-Y373 HydrophobicContact CG-CD2 4.23Å; Y321-Y373 AromaticContact CG-CE1 3.95Å; Y321-Y373 HydrophobicContact CG-CE1 3.95Å; Y321-Y373 AromaticContact CG-CG 3.62Å; Y321-Y373 HydrophobicContact CG-CG 3.62Å; Y321-L375 HydrophobicContact CD2-CD2 4.06Å; Y321-L375 HydrophobicContact CE2-CD2 3.6Å; Y321-L484 HydrophobicContact CD1-CD1 3.86Å; Y321-L484 HydrophobicContact CE1-CD1 3.84Å; Y321-Y486 HydrophobicContact CE1-CE1 4.07Å; Y321-L493 PolarHBondContact OH-O 3.44Å; Y321-T495 HydrophobicContact CE1-CG2 3.85Å; Y321-I499 HydrophobicContact CD1-CD1 3.84Å; Y321-I499 HydrophobicContact CE1-CD1 3.87Å
322C98.8Very high97Very high0 Ų019.4 Ų19.40%010%0.101CC..Hα-helixtrans-59.7-49173.8-179.40000111T318 M319 Y324 E325 L326 V365 T369 L465T318-C322 WeakPolarHBondContact O-CB 3.37Å; T318-C322 PolarHBondContact O-N 2.91Å; M319-C322 WeakPolarHBondContact O-CB 3.46Å; M319-C322 PolarHBondContact O-N 3.49Å; C322-Y324 VanDerWaalsContact C-N 3.32Å; C322-Y324 PolarHBondContact O-N 2.93Å; C322-E325 PolarHBondContact O-N 3.16Å; C322-L326 WeakPolarHBondContact O-CB 3.48Å; C322-L326 VanDerWaalsContact O-CG 3.27Å; C322-L326 WeakPolarHBondContact O-CG 3.36Å; C322-L326 PolarHBondContact O-N 3.41Å; C322-V365 VanDerWaalsContact SG-CG1 3.6Å; C322-T369 HydrophobicContact CB-CG2 3.92Å; C322-L465 HydrophobicContact CB-CD1 4.09Å; C322-L465 HydrophobicContact CB-CD2 4.03Å
323L98.8Very high97.5Very high0 Ų019.4 Ų19.40%010%0.101CC..Hα-helixtrans-64.4-36177.6-68169.3000112.3I175 M179 M319 S320 L326 A327 L465 I468 I469 V474 L501I175-L323 HydrophobicContact CG2-CB 4.22Å; I175-L323 HydrophobicContact CG2-CD1 3.52Å; M179-L323 HydrophobicContact CE-CD1 4.44Å; M179-L323 HydrophobicContact SD-CD1 4.16Å; M319-L323 VanDerWaalsContact O-CG 3.28Å; M319-L323 WeakPolarHBondContact O-CG 3.42Å; M319-L323 PolarHBondContact O-N 2.93Å; S320-L323 PolarHBondContact O-N 3.26Å; L323-L326 PolarHBondContact O-N 3.06Å; L323-A327 VanDerWaalsContact O-CB 3.25Å; L323-A327 WeakPolarHBondContact O-CB 3.47Å; L323-A327 PolarHBondContact O-N 2.99Å; L323-L465 HydrophobicContact CD1-CD2 4.42Å; L323-L465 HydrophobicContact CD2-CD2 3.85Å; L323-L465 HydrophobicContact CG-CD2 3.79Å; L323-I468 HydrophobicContact CD1-CD1 3.69Å; L323-I468 HydrophobicContact CD2-CD1 4.38Å; L323-I468 HydrophobicContact CD2-CG2 3.99Å; L323-I469 HydrophobicContact CD2-CD1 3.92Å; L323-V474 HydrophobicContact CD2-CG2 4.29Å; L323-L501 HydrophobicContact CB-CD1 4.04Å; L323-L501 WeakPolarHBondContact O-CD1 3.24Å
324Y98.7Very high97.9Very high8 Ų821 Ų213%0.03111%0.11CC..Hα-helixtrans-61.9-43173.9171-94.6000112.2S320 Y321 C322 A327 Q328 Y373 T480 E481 I482 L484 I499S320-Y324 WeakPolarHBondContact O-CB 3.26Å; S320-Y324 PolarHBondContact O-N 3.41Å; Y321-Y324 WeakPolarHBondContact O-CB 3.25Å; Y321-Y324 PolarHBondContact O-N 3.33Å; C322-Y324 VanDerWaalsContact C-N 3.32Å; C322-Y324 PolarHBondContact O-N 2.93Å; Y324-A327 PolarHBondContact O-N 3.35Å; Y324-Q328 VanDerWaalsContact CD1-NE2 3.34Å; Y324-Q328 PolarHBondContact O-N 3.03Å; Y324-Q328 PolarHBondContact O-NE2 3.17Å; Y324-Q328 PolarHBondContact OH-OE1 3.24Å; Y324-Y373 WeakPolarHBondContact CD1-OH 3.27Å; Y324-Y373 VanDerWaalsContact CE1-OH 3.22Å; Y324-Y373 WeakPolarHBondContact CE1-OH 3.4Å; Y324-T480 HydrophobicContact CD2-CG2 4.27Å; Y324-T480 HydrophobicContact CE2-CG2 4.05Å; Y324-E481 WeakPolarHBondContact CE2-O 3.48Å; Y324-E481 PolarHBondContact OH-O 3.3Å; Y324-I482 HydrophobicContact CE2-CG1 4.14Å; Y324-L484 HydrophobicContact CD1-CD1 3.86Å; Y324-L484 HydrophobicContact CD1-CG 4.4Å; Y324-L484 HydrophobicContact CD2-CD1 4.07Å; Y324-L484 HydrophobicContact CD2-CD2 4.09Å; Y324-L484 HydrophobicContact CD2-CG 4.11Å; Y324-L484 HydrophobicContact CE1-CD1 3.88Å; Y324-L484 HydrophobicContact CE1-CG 4Å; Y324-L484 HydrophobicContact CE2-CD1 4.08Å; Y324-L484 HydrophobicContact CE2-CD2 3.8Å; Y324-L484 HydrophobicContact CE2-CG 3.67Å; Y324-L484 HydrophobicContact CG-CD1 3.96Å; Y324-L484 HydrophobicContact CG-CG 4.46Å; Y324-I499 HydrophobicContact CD2-CG2 4.22Å
325E98.7Very high98.2Very high22 Ų2224.5 Ų24.510%0.10312%0.118CC..Hα-helixtrans-69.4-44.6175.8-71.6-69.8-172.300112Y321 C322 A327 Q328 N329 Y373 F423Y321-E325 PolarHBondContact O-N 3.32Å; C322-E325 PolarHBondContact O-N 3.16Å; E325-A327 PolarHBondContact O-N 3.22Å; E325-Q328 PolarHBondContact O-N 2.98Å; E325-Q328 VanDerWaalsContact O-N 3.11Å; E325-N329 PolarHBondContact O-N 3.4Å; E325-N329 PolarHBondContact O-ND2 3.01Å; E325-N329 PolarHBondContact OE2-ND2 3.22Å; E325-Y373 HydrophobicContact CG-CE2 3.58Å; E325-Y373 VanDerWaalsContact OE1-CE2 3.28Å; E325-Y373 WeakPolarHBondContact OE1-CE2 3.16Å; E325-Y373 PolarHBondContact OE1-OH 3.42Å; E325-F423 HydrophobicContact CB-CD1 4.18Å; E325-F423 HydrophobicContact CB-CD2 3.7Å; E325-F423 HydrophobicContact CB-CE1 4.15Å; E325-F423 HydrophobicContact CB-CE2 3.72Å; E325-F423 HydrophobicContact CB-CG 3.98Å; E325-F423 HydrophobicContact CB-CZ 3.95Å; E325-F423 HydrophobicContact CG-CD2 3.49Å; E325-F423 VanDerWaalsContact CG-CD2 3.49Å; E325-F423 HydrophobicContact CG-CE2 3.77Å; E325-F423 HydrophobicContact CG-CG 4.07Å; E325-F423 HydrophobicContact CG-CZ 4.5Å
326L98.8Very high98.3Very high0 Ų024.2 Ų24.20%012%0.116CC..Hα-helixtrans-62-32176.5-68.9176.7000112.4C322 L323 Q328 N329 Q330 I332 Q333 L336 V365 I469C322-L326 WeakPolarHBondContact O-CB 3.48Å; C322-L326 VanDerWaalsContact O-CG 3.27Å; C322-L326 WeakPolarHBondContact O-CG 3.36Å; C322-L326 PolarHBondContact O-N 3.41Å; L323-L326 PolarHBondContact O-N 3.06Å; L326-Q328 VanDerWaalsContact C-N 3.28Å; L326-Q328 PolarHBondContact O-N 3.37Å; L326-N329 CarbonylContact O-C 3.01Å; L326-N329 PolarHBondContact O-N 3.2Å; L326-Q330 PolarHBondContact O-NE2 3.12Å; L326-I332 HydrophobicContact CD2-CB 4.43Å; L326-I332 HydrophobicContact CD2-CG2 3.78Å; L326-Q333 HydrophobicContact CB-CB 4.23Å; L326-Q333 HydrophobicContact CB-CG 4.21Å; L326-Q333 HydrophobicContact CD2-CB 4.23Å; L326-Q333 PolarHBondContact O-NE2 2.93Å; L326-L336 HydrophobicContact CD1-CD2 3.75Å; L326-L336 HydrophobicContact CD2-CD2 4.23Å; L326-V365 HydrophobicContact CD1-CG1 4.36Å; L326-V365 HydrophobicContact CD2-CG1 3.97Å; L326-V365 HydrophobicContact CG-CG1 4.32Å; L326-I469 HydrophobicContact CD1-CD1 3.83Å; L326-I469 HydrophobicContact CD1-CG1 4.09Å
327A98.5Very high98.4Very high4 Ų424.8 Ų24.83%0.03312%0.118CC..Hα-helixtrans-66.2-31.4176.600000113L323 Y324 E325 Q330 V474 V476 L501L323-A327 VanDerWaalsContact O-CB 3.25Å; L323-A327 WeakPolarHBondContact O-CB 3.47Å; L323-A327 PolarHBondContact O-N 2.99Å; Y324-A327 PolarHBondContact O-N 3.35Å; E325-A327 PolarHBondContact O-N 3.22Å; A327-Q330 PolarHBondContact O-NE2 2.67Å; A327-V474 WeakPolarHBondContact CA-O 3.45Å; A327-V474 HydrophobicContact CB-CG1 4.13Å; A327-V476 HydrophobicContact CB-CG1 4.2Å; A327-L501 HydrophobicContact CB-CD1 4.02Å; A327-L501 HydrophobicContact CB-CD2 3.77Å; A327-L501 HydrophobicContact CB-CG 4.47Å
328Q98.2Very high98.5Very high68 Ų6829.1 Ų29.132%0.31814%0.141SC..Hα-helixtrans-87.7-22.8176.9-67.7168.6101.400112.6Y324 E325 L326 V476 I482Y324-Q328 VanDerWaalsContact CD1-NE2 3.34Å; Y324-Q328 PolarHBondContact O-N 3.03Å; Y324-Q328 PolarHBondContact O-NE2 3.17Å; Y324-Q328 PolarHBondContact OH-OE1 3.24Å; E325-Q328 PolarHBondContact O-N 2.98Å; E325-Q328 VanDerWaalsContact O-N 3.11Å; L326-Q328 VanDerWaalsContact C-N 3.28Å; L326-Q328 PolarHBondContact O-N 3.37Å; Q328-V476 HydrophobicContact CG-CG1 3.61Å; Q328-I482 HydrophobicContact CG-CD1 4.22Å
329N98.5Very high98.5Very high43 Ų4330.5 Ų30.523%0.2315%0.147CC..  trans-118.376.5-177.1-58.7-82.9000110.7E325 L326 D331 I332 Q333E325-N329 PolarHBondContact O-N 3.4Å; E325-N329 PolarHBondContact O-ND2 3.01Å; E325-N329 PolarHBondContact OE2-ND2 3.22Å; L326-N329 CarbonylContact O-C 3.01Å; L326-N329 PolarHBondContact O-N 3.2Å; N329-D331 VanDerWaalsContact C-N 3.29Å; N329-D331 PolarHBondContact O-N 2.99Å; N329-I332 HydrophobicContact CB-CB 4.12Å; N329-I332 HydrophobicContact CB-CD1 3.82Å; N329-I332 HydrophobicContact CB-CG1 4.1Å; N329-I332 PolarHBondContact O-N 2.85Å; N329-Q333 PolarHBondContact O-N 3.35Å
330Q98.3Very high98.5Very high50 Ų5030.5 Ų30.523%0.23415%0.147CC..Hα-helixtrans-64.6-31.2-174-67.3-64-57.200113.3L326 A327 Q333 D334 V474L326-Q330 PolarHBondContact O-NE2 3.12Å; A327-Q330 PolarHBondContact O-NE2 2.67Å; Q330-Q333 PolarHBondContact O-N 3.24Å; Q330-D334 WeakPolarHBondContact O-CB 3.49Å; Q330-D334 PolarHBondContact O-N 3.24Å; Q330-V474 PolarHBondContact NE2-O 2.85Å
331D98.5Very high98.4Very high114 Ų11433.9 Ų33.961%0.6116%0.163SC*.Hα-helixtrans-63.2-43.3174.762.4-54.5000111.9N329 D334 R335N329-D331 VanDerWaalsContact C-N 3.29Å; N329-D331 PolarHBondContact O-N 2.99Å; D331-D334 PolarHBondContact O-N 3.02Å; D331-R335 WeakPolarHBondContact O-CB 3.47Å; D331-R335 PolarHBondContact O-N 3.07Å
332I98.8Very high98.3Very high13 Ų1337 Ų377%0.06718%0.183CC..Hα-helixtrans-66.1-41.6174.6-62177.7000110.1L326 N329 R335 L336 Y361 V365 F423 P425L326-I332 HydrophobicContact CD2-CB 4.43Å; L326-I332 HydrophobicContact CD2-CG2 3.78Å; N329-I332 HydrophobicContact CB-CB 4.12Å; N329-I332 HydrophobicContact CB-CD1 3.82Å; N329-I332 HydrophobicContact CB-CG1 4.1Å; N329-I332 PolarHBondContact O-N 2.85Å; I332-R335 PolarHBondContact O-N 3.16Å; I332-L336 VanDerWaalsContact O-CB 3.29Å; I332-L336 WeakPolarHBondContact O-CB 3.39Å; I332-L336 PolarHBondContact O-N 3.41Å; I332-Y361 HydrophobicContact CG2-CE1 4.1Å; I332-V365 HydrophobicContact CG2-CG2 4.1Å; I332-F423 HydrophobicContact CD1-CD1 3.74Å; I332-F423 HydrophobicContact CD1-CE1 4.15Å; I332-F423 HydrophobicContact CG2-CE1 4.21Å; I332-P425 HydrophobicContact CD1-CG 4.21Å; I332-P425 HydrophobicContact CG2-CG 3.89Å
333Q98.8Very high98.2Very high0 Ų037.6 Ų37.60%019%0.186CC..Hα-helixtrans-62.8-44177-166.8-175.9135.500112.4L326 N329 Q330 L336 R337 I469 V474L326-Q333 HydrophobicContact CB-CB 4.23Å; L326-Q333 HydrophobicContact CB-CG 4.21Å; L326-Q333 HydrophobicContact CD2-CB 4.23Å; L326-Q333 PolarHBondContact O-NE2 2.93Å; N329-Q333 PolarHBondContact O-N 3.35Å; Q330-Q333 PolarHBondContact O-N 3.24Å; Q333-L336 PolarHBondContact O-N 3.39Å; Q333-R337 WeakPolarHBondContact O-CB 3.32Å; Q333-R337 PolarHBondContact O-N 3.42Å; Q333-I469 HydrophobicContact CG-CD1 4.06Å; Q333-I469 HydrophobicContact CG-CG2 4.49Å; Q333-V474 PolarHBondContact NE2-O 3.38Å
334D98.6Very high97.9Very high51 Ų5138.6 Ų38.627%0.27319%0.191SC..Hα-helixtrans-66.9-41.2179.4-71.2-19.5000110.8Q330 D331 R337 N338 R473Q330-D334 WeakPolarHBondContact O-CB 3.49Å; Q330-D334 PolarHBondContact O-N 3.24Å; D331-D334 PolarHBondContact O-N 3.02Å; D334-R337 PolarHBondContact O-N 3.27Å; D334-R337 IonicContact OD1-CZ 3.68Å; D334-R337 IonicContact OD1-NH1 2.76Å; D334-R337 PolarHBondContact OD1-NH1 3.49Å; D334-N338 PolarHBondContact O-N 3.3Å; D334-N338 PolarHBondContact O-ND2 3Å; D334-N338 PolarHBondContact O-OD1 2.96Å; D334-R473 IonicContact OD1-CZ 3.43Å; D334-R473 IonicContact OD1-NH1 2.73Å; D334-R473 PolarHBondContact OD1-NH1 3.14Å; D334-R473 VanDerWaalsContact OD1-NH1 3.11Å; D334-R473 IonicContact OD1-NH2 2.74Å; D334-R473 PolarHBondContact OD1-NH2 3.07Å; D334-R473 VanDerWaalsContact OD1-NH2 3.07Å; D334-R473 IonicContact OD2-NH1 3.29Å; D334-R473 IonicContact OD2-NH2 3.12Å
335R98.5Very high97.6Very high120 Ų12045.2 Ų45.245%0.45322%0.222SC..Hα-helixtrans-62.3-44.9172.6-180174.5171.5-162.6-6.1112.5D331 I332 R337 N338 E339 Y361 E426D331-R335 WeakPolarHBondContact O-CB 3.47Å; D331-R335 PolarHBondContact O-N 3.07Å; I332-R335 PolarHBondContact O-N 3.16Å; R335-R337 VanDerWaalsContact C-N 3.32Å; R335-R337 PolarHBondContact O-N 3.21Å; R335-N338 PolarHBondContact O-N 3.28Å; R335-E339 PolarHBondContact O-N 3.47Å; R335-E339 VanDerWaalsContact O-N 3.11Å; R335-Y361 HydrophobicContact CB-CE1 4.03Å; R335-Y361 HydrophobicContact CG-CD1 4.04Å; R335-Y361 HydrophobicContact CG-CE1 3.73Å; R335-Y361 PolarHBondContact NH1-OH 2.83Å; R335-E426 IonicContact CZ-OE1 3.19Å; R335-E426 IonicContact NH1-OE1 3.11Å; R335-E426 PolarHBondContact NH1-OE1 3.47Å; R335-E426 IonicContact NH2-OE1 3.62Å; R335-E426 PolarHBondContact NH2-OE1 3.06Å
336L98.7Very high97.2Very high0 Ų050.6 Ų50.60%025%0.248CC..Hα-helixtrans-61-43176.5175.760.8000111.5L326 I332 Q333 N338 E339 I340 Y361 L362 V365 I469L326-L336 HydrophobicContact CD1-CD2 3.75Å; L326-L336 HydrophobicContact CD2-CD2 4.23Å; I332-L336 VanDerWaalsContact O-CB 3.29Å; I332-L336 WeakPolarHBondContact O-CB 3.39Å; I332-L336 PolarHBondContact O-N 3.41Å; Q333-L336 PolarHBondContact O-N 3.39Å; L336-N338 VanDerWaalsContact C-N 3.35Å; L336-N338 PolarHBondContact O-N 2.82Å; L336-E339 PolarHBondContact O-N 3.47Å; L336-I340 HydrophobicContact CD1-CD1 3.92Å; L336-I340 HydrophobicContact CD1-CG1 4.28Å; L336-I340 HydrophobicContact CG-CD1 3.79Å; L336-I340 WeakPolarHBondContact O-CD1 3.47Å; L336-I340 VanDerWaalsContact O-CG1 3.3Å; L336-I340 WeakPolarHBondContact O-CG1 3.48Å; L336-I340 PolarHBondContact O-N 2.96Å; L336-Y361 HydrophobicContact CB-CD1 4.02Å; L336-Y361 HydrophobicContact CB-CE1 4.27Å; L336-Y361 HydrophobicContact CD1-CD1 4.23Å; L336-L362 VanDerWaalsContact CD1-CA 3.45Å; L336-L362 HydrophobicContact CD1-CB 3.72Å; L336-L362 HydrophobicContact CD1-CD1 4Å; L336-L362 HydrophobicContact CD1-CG 4.45Å; L336-L362 HydrophobicContact CD2-CD1 4.27Å; L336-V365 HydrophobicContact CD2-CG1 4.24Å; L336-V365 HydrophobicContact CD2-CG2 4.34Å; L336-I469 HydrophobicContact CD2-CG1 4.27Å; L336-I469 HydrophobicContact CD2-CG2 4.27Å; L336-I469 HydrophobicContact CG-CG2 4.17Å
337R98.3Very high96.8Very high12 Ų1254 Ų545%0.04526%0.264CS..Hα-helixtrans-60.5-45176.1-177.3177.8-59.1102.5-0.7111.9Q333 D334 R335 E339 I340 Q341 I469 F472 I506Q333-R337 WeakPolarHBondContact O-CB 3.32Å; Q333-R337 PolarHBondContact O-N 3.42Å; D334-R337 PolarHBondContact O-N 3.27Å; D334-R337 IonicContact OD1-CZ 3.68Å; D334-R337 IonicContact OD1-NH1 2.76Å; D334-R337 PolarHBondContact OD1-NH1 3.49Å; R335-R337 VanDerWaalsContact C-N 3.32Å; R335-R337 PolarHBondContact O-N 3.21Å; R337-E339 VanDerWaalsContact C-N 3.34Å; R337-E339 PolarHBondContact O-N 3.21Å; R337-I340 PolarHBondContact O-N 3.4Å; R337-Q341 HydrophobicContact CG-CG 4.26Å; R337-Q341 WeakPolarHBondContact O-CB 3.42Å; R337-Q341 WeakPolarHBondContact O-CG 3.43Å; R337-Q341 PolarHBondContact O-N 3.04Å; R337-I469 HydrophobicContact CB-CG2 3.86Å; R337-I469 WeakPolarHBondContact CG-O 3.42Å; R337-I469 PolarHBondContact NE-O 3.09Å; R337-F472 PolarHBondContact NH2-O 3.17Å; R337-F472 VanDerWaalsContact NH2-O 3.15Å; R337-I506 VanDerWaalsContact CD-CD1 3.5Å
338N98.2Very high96.3Very high93 Ų9362.2 Ų62.250%0.49730%0.301SS..Hα-helixtrans-59-45.7178-68-16.5000111D334 R335 L336 I340 Q341 T342D334-N338 PolarHBondContact O-N 3.3Å; D334-N338 PolarHBondContact O-ND2 3Å; D334-N338 PolarHBondContact O-OD1 2.96Å; R335-N338 PolarHBondContact O-N 3.28Å; L336-N338 VanDerWaalsContact C-N 3.35Å; L336-N338 PolarHBondContact O-N 2.82Å; N338-I340 PolarHBondContact O-N 3.03Å; N338-Q341 PolarHBondContact O-N 3.36Å; N338-T342 WeakPolarHBondContact O-CB 3.49Å; N338-T342 PolarHBondContact O-N 2.73Å; N338-T342 PolarHBondContact O-OG1 2.88Å; N338-T342 VanDerWaalsContact O-OG1 3.05Å
339E98.2Very high95.5Very high42 Ų4261.4 Ų61.420%0.19631%0.311CS..Hα-helixtrans-57.4-49.3174179-175.5-114.700111.5R335 L336 R337 Q341 T342 V343 T360 Y361 L362R335-E339 PolarHBondContact O-N 3.47Å; R335-E339 VanDerWaalsContact O-N 3.11Å; L336-E339 PolarHBondContact O-N 3.47Å; R337-E339 VanDerWaalsContact C-N 3.34Å; R337-E339 PolarHBondContact O-N 3.21Å; E339-Q341 VanDerWaalsContact C-N 3.34Å; E339-Q341 PolarHBondContact O-N 2.93Å; E339-T342 PolarHBondContact O-N 3.46Å; E339-V343 HydrophobicContact CG-CG2 4.36Å; E339-V343 WeakPolarHBondContact O-CB 3.26Å; E339-V343 WeakPolarHBondContact O-CG2 3.44Å; E339-V343 PolarHBondContact O-N 3.16Å; E339-T360 PolarHBondContact OE1-N 3.36Å; E339-T360 PolarHBondContact OE2-N 3.44Å; E339-Y361 VanDerWaalsContact CD-CB 3.44Å; E339-Y361 VanDerWaalsContact CD-N 3.26Å; E339-Y361 WeakPolarHBondContact OE1-CB 3.43Å; E339-Y361 PolarHBondContact OE1-N 2.84Å; E339-Y361 WeakPolarHBondContact OE2-CA 3.48Å; E339-Y361 VanDerWaalsContact OE2-CB 3.28Å; E339-Y361 WeakPolarHBondContact OE2-CB 3.5Å; E339-Y361 PolarHBondContact OE2-N 2.84Å; E339-L362 PolarHBondContact OE2-N 2.85Å
340I97.7Very high94.9Very high0 Ų065 Ų650%033%0.327CS..Hα-helixtrans-61.5-44-177.7-66.7160.2000110.6L336 R337 N338 V343 L344 M359 A466 I469L336-I340 HydrophobicContact CD1-CD1 3.92Å; L336-I340 HydrophobicContact CD1-CG1 4.28Å; L336-I340 HydrophobicContact CG-CD1 3.79Å; L336-I340 WeakPolarHBondContact O-CD1 3.47Å; L336-I340 VanDerWaalsContact O-CG1 3.3Å; L336-I340 WeakPolarHBondContact O-CG1 3.48Å; L336-I340 PolarHBondContact O-N 2.96Å; R337-I340 PolarHBondContact O-N 3.4Å; N338-I340 PolarHBondContact O-N 3.03Å; I340-V343 PolarHBondContact O-N 2.81Å; I340-L344 HydrophobicContact CG2-CD1 3.79Å; I340-L344 HydrophobicContact CG2-CG 4.3Å; I340-L344 WeakPolarHBondContact O-CB 3.47Å; I340-L344 WeakPolarHBondContact O-CG 3.48Å; I340-L344 PolarHBondContact O-N 2.85Å; I340-M359 HydrophobicContact CG1-SD 4.09Å; I340-M359 HydrophobicContact CG2-CE 4.04Å; I340-A466 HydrophobicContact CD1-CB 4.45Å; I340-A466 HydrophobicContact CG2-CB 4.39Å; I340-I469 HydrophobicContact CD1-CB 3.94Å; I340-I469 HydrophobicContact CD1-CG2 3.88Å
341Q95.9Very high94.5Very high70 Ų7063.7 Ų63.733%0.32732%0.321SS..Hα-helixtrans-63.9-47.5179.4-74.8178.8-16.300111.5R337 N338 E339 V343 L344 E345R337-Q341 HydrophobicContact CG-CG 4.26Å; R337-Q341 WeakPolarHBondContact O-CB 3.42Å; R337-Q341 WeakPolarHBondContact O-CG 3.43Å; R337-Q341 PolarHBondContact O-N 3.04Å; N338-Q341 PolarHBondContact O-N 3.36Å; E339-Q341 VanDerWaalsContact C-N 3.34Å; E339-Q341 PolarHBondContact O-N 2.93Å; Q341-V343 PolarHBondContact O-N 2.92Å; Q341-L344 PolarHBondContact O-N 3.45Å; Q341-E345 WeakPolarHBondContact O-CG 3.41Å; Q341-E345 PolarHBondContact O-N 2.8Å
342T96.6Very high94.2Very high68 Ų6860.2 Ų60.242%0.41730%0.304SS..Hα-helixtrans-58.4-47.3176.8-60.10000111.8N338 E339 L344 E345 E346N338-T342 WeakPolarHBondContact O-CB 3.49Å; N338-T342 PolarHBondContact O-N 2.73Å; N338-T342 PolarHBondContact O-OG1 2.88Å; N338-T342 VanDerWaalsContact O-OG1 3.05Å; E339-T342 PolarHBondContact O-N 3.46Å; T342-L344 VanDerWaalsContact C-N 3.3Å; T342-L344 PolarHBondContact O-N 3.04Å; T342-E345 PolarHBondContact O-N 2.87Å; T342-E346 WeakPolarHBondContact O-CG 3.49Å; T342-E346 PolarHBondContact O-N 3.17Å
343V96.1Very high93.7Very high12 Ų1262.6 Ų62.67%0.07331%0.313CS..Hα-helixtrans-64.7-35.4178.9171.30000111.8E339 I340 Q341 Q347 S355 A358 M359E339-V343 HydrophobicContact CG-CG2 4.36Å; E339-V343 WeakPolarHBondContact O-CB 3.26Å; E339-V343 WeakPolarHBondContact O-CG2 3.44Å; E339-V343 PolarHBondContact O-N 3.16Å; I340-V343 PolarHBondContact O-N 2.81Å; Q341-V343 PolarHBondContact O-N 2.92Å; V343-Q347 WeakPolarHBondContact O-CB 3.14Å; V343-Q347 WeakPolarHBondContact O-CG 3.26Å; V343-Q347 PolarHBondContact O-N 3.03Å; V343-S355 WeakPolarHBondContact CG1-O 3.33Å; V343-A358 HydrophobicContact CG1-CB 4.11Å; V343-A358 HydrophobicContact CG2-CB 4.39Å; V343-M359 HydrophobicContact CB-CE 4.26Å; V343-M359 HydrophobicContact CB-CG 4.28Å; V343-M359 HydrophobicContact CG1-CE 3.91Å; V343-M359 HydrophobicContact CG1-CG 4.09Å; V343-M359 HydrophobicContact CG2-CG 4.28Å
344L93.4Very high93.2Very high20 Ų2066.7 Ų66.711%0.10533%0.332CS..Hα-helixtrans-69.1-41.5175.8-74.1174.3000111.8I340 Q341 T342 E346 Q347 E348 G349 L351 M359I340-L344 HydrophobicContact CG2-CD1 3.79Å; I340-L344 HydrophobicContact CG2-CG 4.3Å; I340-L344 WeakPolarHBondContact O-CB 3.47Å; I340-L344 WeakPolarHBondContact O-CG 3.48Å; I340-L344 PolarHBondContact O-N 2.85Å; Q341-L344 PolarHBondContact O-N 3.45Å; T342-L344 VanDerWaalsContact C-N 3.3Å; T342-L344 PolarHBondContact O-N 3.04Å; L344-E346 VanDerWaalsContact C-N 3.32Å; L344-E346 PolarHBondContact O-N 3.08Å; L344-Q347 CarbonylContact O-C 3.47Å; L344-Q347 VanDerWaalsContact O-C 3.31Å; L344-Q347 PolarHBondContact O-N 2.95Å; L344-E348 PolarHBondContact O-N 3.1Å; L344-G349 WeakPolarHBondContact O-CA 3.5Å; L344-G349 PolarHBondContact O-N 2.97Å; L344-L351 HydrophobicContact CD2-CD2 3.67Å; L344-L351 HydrophobicContact CD2-CG 3.81Å; L344-M359 HydrophobicContact CG-CE 4.49Å
345E92.6Very high92.9Very high147 Ų14764.2 Ų64.269%0.68732%0.319SS*.Hα-helixtrans-59.3-43.1175.8-73.7170.9-176.600111.5Q341 T342 Q347 E348Q341-E345 WeakPolarHBondContact O-CG 3.41Å; Q341-E345 PolarHBondContact O-N 2.8Å; T342-E345 PolarHBondContact O-N 2.87Å; E345-Q347 PolarHBondContact O-N 2.92Å; E345-E348 PolarHBondContact O-N 3.49Å
346E90.9Very high92.5Very high136 Ų13658.9 Ų58.964%0.63630%0.299SS*.THydrogen-bonded Turntrans-64.6-17.7174.6-70.2176.7177.600113.8T342 L344T342-E346 WeakPolarHBondContact O-CG 3.49Å; T342-E346 PolarHBondContact O-N 3.17Å; L344-E346 VanDerWaalsContact C-N 3.32Å; L344-E346 PolarHBondContact O-N 3.08Å
347Q88.8Confident92.1Very high72 Ų7265.6 Ų65.634%0.33633%0.328SS..THydrogen-bonded Turntrans-116.829.4-175.8-61.7-71.4-53.200112V343 L344 E345 G349 Q350 T352V343-Q347 WeakPolarHBondContact O-CB 3.14Å; V343-Q347 WeakPolarHBondContact O-CG 3.26Å; V343-Q347 PolarHBondContact O-N 3.03Å; L344-Q347 CarbonylContact O-C 3.47Å; L344-Q347 VanDerWaalsContact O-C 3.31Å; L344-Q347 PolarHBondContact O-N 2.95Å; E345-Q347 PolarHBondContact O-N 2.92Å; Q347-G349 PolarHBondContact O-N 3.28Å; Q347-Q350 PolarHBondContact O-N 3.04Å; Q347-T352 PolarHBondContact OE1-OG1 3.33Å
348E88.2Confident91.9Very high175 Ų17567.5 Ų67.582%0.81835%0.346SS*.THydrogen-bonded Turntrans57.131.7176.6-56.8178.2-168.800113.6L344 E345 Q350L344-E348 PolarHBondContact O-N 3.1Å; E345-E348 PolarHBondContact O-N 3.49Å; E348-Q350 VanDerWaalsContact C-N 3.27Å; E348-Q350 PolarHBondContact O-N 2.85Å
349G82.8Confident91.8Very high52 Ų5263 Ų6354%0.53632%0.323SS..THydrogen-bonded Turntrans75.47.8-17900000114.7L344 Q347L344-G349 WeakPolarHBondContact O-CA 3.5Å; L344-G349 PolarHBondContact O-N 2.97Å; Q347-G349 PolarHBondContact O-N 3.28Å
350Q85.2Confident91.7Very high119 Ų11964 Ų6456%0.55633%0.331SS*.  trans-102.6134.4-175.6-60.8-171.712.100112.8Q347 E348 T352Q347-Q350 PolarHBondContact O-N 3.04Å; E348-Q350 VanDerWaalsContact C-N 3.27Å; E348-Q350 PolarHBondContact O-N 2.85Å; Q350-T352 HydrophobicContact CB-CG2 4.15Å; Q350-T352 PolarHBondContact O-N 2.81Å
351L90.1Very high91.8Very high22 Ų2264.7 Ų64.712%0.11533%0.334CS..  trans-76.591.1167.2-77.5171.4000109.8F146 I150 L344 S355 I356 M359 A466 Q467F146-L351 VanDerWaalsContact CE1-O 3.22Å; F146-L351 WeakPolarHBondContact CE1-O 3.48Å; I150-L351 HydrophobicContact CD1-CB 3.78Å; L344-L351 HydrophobicContact CD2-CD2 3.67Å; L344-L351 HydrophobicContact CD2-CG 3.81Å; L351-S355 WeakPolarHBondContact CA-OG 2.93Å; L351-I356 HydrophobicContact CD2-CD1 3.97Å; L351-I356 HydrophobicContact CD2-CG1 4.29Å; L351-M359 HydrophobicContact CD2-CE 3.81Å; L351-A466 HydrophobicContact CD2-CB 4.23Å; L351-Q467 HydrophobicContact CD1-CG 3.68Å
352T91.1Very high91.9Very high40 Ų4061.3 Ų61.325%0.24532%0.318CS..  trans-91.8165.5172.572.90000111.8F146 Q347 Q350 E354 S355 I356F146-T352 VanDerWaalsContact CE1-C 3.48Å; F146-T352 WeakPolarHBondContact CZ-O 3.48Å; Q347-T352 PolarHBondContact OE1-OG1 3.33Å; Q350-T352 HydrophobicContact CB-CG2 4.15Å; Q350-T352 PolarHBondContact O-N 2.81Å; T352-E354 PolarHBondContact O-N 2.88Å; T352-S355 PolarHBondContact N-OG 3.24Å; T352-S355 PolarHBondContact O-N 3.28Å; T352-S355 PolarHBondContact O-OG 2.96Å; T352-S355 PolarHBondContact OG1-N 3.47Å; T352-I356 PolarHBondContact O-N 3.35Å
353Y88.6Confident92Very high63 Ų6359.8 Ų59.825%0.24731%0.307CS..Hα-helixtrans-59.3-34.8175.5-171.4-91.1000112.2M142 K143 F146 K357M142-Y353 HydrophobicContact CB-CE2 4.14Å; K143-Y353 HydrophobicContact CB-CD2 4.24Å; K143-Y353 HydrophobicContact CB-CE2 4.29Å; K143-Y353 HydrophobicContact CB-CG 4.47Å; K143-Y353 HydrophobicContact CG-CD2 4.42Å; K143-Y353 HydrophobicContact CG-CG 4.26Å; F146-Y353 HydrophobicContact CB-CD2 4.14Å; F146-Y353 AromaticContact CD2-CD2 3.61Å; F146-Y353 HydrophobicContact CD2-CD2 3.61Å; F146-Y353 HydrophobicContact CD2-CE2 4.47Å; F146-Y353 HydrophobicContact CD2-CG 4.41Å; F146-Y353 HydrophobicContact CE2-CD2 4.21Å; F146-Y353 AromaticContact CG-CD2 3.98Å; F146-Y353 HydrophobicContact CG-CD2 3.98Å; Y353-K357 PolarHBondContact O-N 3.03Å
354E88.9Confident92.1Very high86 Ų8659.8 Ų59.840%0.40231%0.307SS..Hα-helixtrans-75.9-36.5177.7-56.4-52.7145.100111.7T352 I356 K357 A358T352-E354 PolarHBondContact O-N 2.88Å; E354-I356 VanDerWaalsContact C-N 3.35Å; E354-I356 PolarHBondContact O-N 2.98Å; E354-K357 WeakPolarHBondContact O-CB 3.29Å; E354-K357 PolarHBondContact O-N 3.4Å; E354-K357 VanDerWaalsContact O-N 3.07Å; E354-A358 PolarHBondContact O-N 3.42Å
355S91.4Very high92.4Very high0 Ų058.9 Ų58.90%030%0.302CS..Hα-helixtrans-56.2-47.9174.875.50000111.7V343 L351 T352 K357 A358 M359V343-S355 WeakPolarHBondContact CG1-O 3.33Å; L351-S355 WeakPolarHBondContact CA-OG 2.93Å; T352-S355 PolarHBondContact N-OG 3.24Å; T352-S355 PolarHBondContact O-N 3.28Å; T352-S355 PolarHBondContact O-OG 2.96Å; T352-S355 PolarHBondContact OG1-N 3.47Å; S355-K357 PolarHBondContact O-N 3.06Å; S355-A358 WeakPolarHBondContact O-CB 3.42Å; S355-A358 PolarHBondContact O-N 3.31Å; S355-M359 WeakPolarHBondContact O-CG 3.42Å; S355-M359 PolarHBondContact O-N 3.06Å
356I91.9Very high92.7Very high7 Ų752.1 Ų52.14%0.03627%0.27CS..Hα-helixtrans-65-29.6179.2-73.3-74.6000111.8F146 L351 T352 E354 M359 R462 I463 A466F146-I356 HydrophobicContact CE2-CB 4.45Å; F146-I356 HydrophobicContact CE2-CG1 4.1Å; F146-I356 HydrophobicContact CZ-CG1 4.16Å; L351-I356 HydrophobicContact CD2-CD1 3.97Å; L351-I356 HydrophobicContact CD2-CG1 4.29Å; T352-I356 PolarHBondContact O-N 3.35Å; E354-I356 VanDerWaalsContact C-N 3.35Å; E354-I356 PolarHBondContact O-N 2.98Å; I356-M359 HydrophobicContact CD1-SD 4.06Å; I356-R462 HydrophobicContact CD1-CB 4.05Å; I356-R462 HydrophobicContact CG2-CB 3.73Å; I356-R462 HydrophobicContact CG2-CG 4.26Å; I356-I463 HydrophobicContact CD1-CG1 4.01Å; I356-I463 HydrophobicContact CG1-CG1 4.17Å; I356-A466 HydrophobicContact CD1-CB 4.21Å
357K89.9Confident93Very high141 Ų14146.5 Ų46.561%0.61325%0.246SC*.Hα-helixtrans-75-31.2175.7-174.8-176.3169.2-163.10111.8Y353 E354 S355Y353-K357 PolarHBondContact O-N 3.03Å; E354-K357 WeakPolarHBondContact O-CB 3.29Å; E354-K357 PolarHBondContact O-N 3.4Å; E354-K357 VanDerWaalsContact O-N 3.07Å; S355-K357 PolarHBondContact O-N 3.06Å
358A93Very high93.5Very high52 Ų5243.1 Ų43.143%0.4323%0.23SC..Hα-helixtrans-74.2-2517900000113.5V343 E354 S355 T360V343-A358 HydrophobicContact CG1-CB 4.11Å; V343-A358 HydrophobicContact CG2-CB 4.39Å; E354-A358 PolarHBondContact O-N 3.42Å; S355-A358 WeakPolarHBondContact O-CB 3.42Å; S355-A358 PolarHBondContact O-N 3.31Å; A358-T360 PolarHBondContact O-N 3.2Å; A358-T360 PolarHBondContact O-OG1 3.07Å
359M96.2Very high94Very high0 Ų034.8 Ų34.80%019%0.192CC..  trans-70.186.6178-62.5170.9-173.800111.6I340 V343 L344 L351 S355 I356 L362 N363 A466I340-M359 HydrophobicContact CG1-SD 4.09Å; I340-M359 HydrophobicContact CG2-CE 4.04Å; V343-M359 HydrophobicContact CB-CE 4.26Å; V343-M359 HydrophobicContact CB-CG 4.28Å; V343-M359 HydrophobicContact CG1-CE 3.91Å; V343-M359 HydrophobicContact CG1-CG 4.09Å; V343-M359 HydrophobicContact CG2-CG 4.28Å; L344-M359 HydrophobicContact CG-CE 4.49Å; L351-M359 HydrophobicContact CD2-CE 3.81Å; S355-M359 WeakPolarHBondContact O-CG 3.42Å; S355-M359 PolarHBondContact O-N 3.06Å; I356-M359 HydrophobicContact CD1-SD 4.06Å; M359-L362 HydrophobicContact CB-CB 3.74Å; M359-L362 HydrophobicContact CB-CD2 4.07Å; M359-L362 HydrophobicContact SD-CD2 3.71Å; M359-N363 PolarHBondContact O-N 2.88Å; M359-N363 PolarHBondContact O-ND2 3Å; M359-A466 HydrophobicContact SD-CB 4.12Å
360T97.3Very high94.8Very high62 Ų6232.7 Ų32.738%0.3817%0.168SC..Hα-helixtrans-76.8-43.9-173.7-63.30000111.3E339 A358 N363 Q364 P430E339-T360 PolarHBondContact OE1-N 3.36Å; E339-T360 PolarHBondContact OE2-N 3.44Å; A358-T360 PolarHBondContact O-N 3.2Å; A358-T360 PolarHBondContact O-OG1 3.07Å; T360-N363 VanDerWaalsContact O-CB 3.31Å; T360-N363 WeakPolarHBondContact O-CB 3.39Å; T360-N363 PolarHBondContact O-N 2.86Å; T360-N363 VanDerWaalsContact O-N 3.13Å; T360-Q364 WeakPolarHBondContact O-CG 3.37Å; T360-Q364 PolarHBondContact O-N 3.39Å; T360-Q364 VanDerWaalsContact O-N 3.09Å; T360-P430 HydrophobicContact CG2-CG 4.37Å
361Y98.6Very high95.4Very high14 Ų1427 Ų276%0.05514%0.142CC..Hα-helixtrans-67.4-36.8177.8-161.1-113.6000111.6I332 R335 L336 E339 N363 Q364 V365 P425I332-Y361 HydrophobicContact CG2-CE1 4.1Å; R335-Y361 HydrophobicContact CB-CE1 4.03Å; R335-Y361 HydrophobicContact CG-CD1 4.04Å; R335-Y361 HydrophobicContact CG-CE1 3.73Å; R335-Y361 PolarHBondContact NH1-OH 2.83Å; L336-Y361 HydrophobicContact CB-CD1 4.02Å; L336-Y361 HydrophobicContact CB-CE1 4.27Å; L336-Y361 HydrophobicContact CD1-CD1 4.23Å; E339-Y361 VanDerWaalsContact CD-CB 3.44Å; E339-Y361 VanDerWaalsContact CD-N 3.26Å; E339-Y361 WeakPolarHBondContact OE1-CB 3.43Å; E339-Y361 PolarHBondContact OE1-N 2.84Å; E339-Y361 WeakPolarHBondContact OE2-CA 3.48Å; E339-Y361 VanDerWaalsContact OE2-CB 3.28Å; E339-Y361 WeakPolarHBondContact OE2-CB 3.5Å; E339-Y361 PolarHBondContact OE2-N 2.84Å; Y361-N363 PolarHBondContact O-N 2.87Å; Y361-Q364 HydrophobicContact CD2-CB 4.44Å; Y361-Q364 WeakPolarHBondContact O-CB 3.09Å; Y361-Q364 PolarHBondContact O-N 3.2Å; Y361-V365 HydrophobicContact CD1-CG2 4.07Å; Y361-V365 HydrophobicContact CE1-CG2 3.95Å; Y361-V365 WeakPolarHBondContact O-CG2 3.43Å; Y361-V365 PolarHBondContact O-N 2.98Å; Y361-P425 HydrophobicContact CE2-CB 3.86Å
362L98.6Very high95.7Very high0 Ų026.1 Ų26.10%014%0.137CC..Hα-helixtrans-54.7-41.616918059.3000112L336 E339 M359 Q364 V365 I366 R462 L465 A466L336-L362 VanDerWaalsContact CD1-CA 3.45Å; L336-L362 HydrophobicContact CD1-CB 3.72Å; L336-L362 HydrophobicContact CD1-CD1 4Å; L336-L362 HydrophobicContact CD1-CG 4.45Å; L336-L362 HydrophobicContact CD2-CD1 4.27Å; E339-L362 PolarHBondContact OE2-N 2.85Å; M359-L362 HydrophobicContact CB-CB 3.74Å; M359-L362 HydrophobicContact CB-CD2 4.07Å; M359-L362 HydrophobicContact SD-CD2 3.71Å; L362-Q364 VanDerWaalsContact C-N 3.34Å; L362-V365 PolarHBondContact O-N 2.81Å; L362-I366 HydrophobicContact CD1-CD1 3.98Å; L362-I366 HydrophobicContact CD1-CG1 4.33Å; L362-I366 HydrophobicContact CG-CD1 4.01Å; L362-I366 VanDerWaalsContact O-CG1 3.3Å; L362-I366 WeakPolarHBondContact O-CG1 3.39Å; L362-I366 PolarHBondContact O-N 3.37Å; L362-R462 HydrophobicContact CD2-CB 3.93Å; L362-R462 HydrophobicContact CD2-CG 4.15Å; L362-R462 HydrophobicContact CG-CG 4.44Å; L362-L465 HydrophobicContact CD1-CB 4.04Å; L362-L465 HydrophobicContact CD1-CD1 4.43Å; L362-A466 HydrophobicContact CD2-CB 4.2Å
363N98.1Very high96Very high35 Ų3524.7 Ų24.719%0.18713%0.127CC..Hα-helixtrans-65.9-37.9176.2-70.5-42.9000112.7M359 T360 Y361 S367 R462M359-N363 PolarHBondContact O-N 2.88Å; M359-N363 PolarHBondContact O-ND2 3Å; T360-N363 VanDerWaalsContact O-CB 3.31Å; T360-N363 WeakPolarHBondContact O-CB 3.39Å; T360-N363 PolarHBondContact O-N 2.86Å; T360-N363 VanDerWaalsContact O-N 3.13Å; Y361-N363 PolarHBondContact O-N 2.87Å; N363-S367 VanDerWaalsContact O-CB 3.28Å; N363-S367 WeakPolarHBondContact O-CB 3.17Å; N363-S367 PolarHBondContact O-N 2.85Å; N363-S367 PolarHBondContact O-OG 3.46Å; N363-R462 PolarHBondContact OD1-NE 3.39Å; N363-R462 PolarHBondContact OD1-NH2 2.86Å
364Q98.8Very high96.4Very high13 Ų1321.7 Ų21.76%0.06112%0.115CC..Hα-helixtrans-63.9-48.5176.3-68.5178.310.600111.3T360 Y361 L362 I366 S367 E368 P425 F428T360-Q364 WeakPolarHBondContact O-CG 3.37Å; T360-Q364 PolarHBondContact O-N 3.39Å; T360-Q364 VanDerWaalsContact O-N 3.09Å; Y361-Q364 HydrophobicContact CD2-CB 4.44Å; Y361-Q364 WeakPolarHBondContact O-CB 3.09Å; Y361-Q364 PolarHBondContact O-N 3.2Å; L362-Q364 VanDerWaalsContact C-N 3.34Å; Q364-I366 PolarHBondContact O-N 2.92Å; Q364-S367 PolarHBondContact O-N 2.75Å; Q364-S367 VanDerWaalsContact O-N 3.14Å; Q364-E368 WeakPolarHBondContact O-CB 3.21Å; Q364-E368 PolarHBondContact O-N 2.83Å; Q364-P425 HydrophobicContact CB-CB 3.98Å; Q364-P425 WeakPolarHBondContact CB-O 3.43Å; Q364-F428 HydrophobicContact CB-CB 4.17Å; Q364-F428 HydrophobicContact CG-CB 4.09Å; Q364-F428 WeakPolarHBondContact CG-O 3.49Å
365V98.9Very high96.7Very high0 Ų018.3 Ų18.30%010%0.1CC..Hα-helixtrans-59.5-45.8178173.10000111.3C322 L326 I332 L336 Y361 L362 S367 T369 F423 P425C322-V365 VanDerWaalsContact SG-CG1 3.6Å; L326-V365 HydrophobicContact CD1-CG1 4.36Å; L326-V365 HydrophobicContact CD2-CG1 3.97Å; L326-V365 HydrophobicContact CG-CG1 4.32Å; I332-V365 HydrophobicContact CG2-CG2 4.1Å; L336-V365 HydrophobicContact CD2-CG1 4.24Å; L336-V365 HydrophobicContact CD2-CG2 4.34Å; Y361-V365 HydrophobicContact CD1-CG2 4.07Å; Y361-V365 HydrophobicContact CE1-CG2 3.95Å; Y361-V365 WeakPolarHBondContact O-CG2 3.43Å; Y361-V365 PolarHBondContact O-N 2.98Å; L362-V365 PolarHBondContact O-N 2.81Å; V365-S367 VanDerWaalsContact C-N 3.33Å; V365-S367 PolarHBondContact O-N 2.87Å; V365-T369 WeakPolarHBondContact O-CB 3.4Å; V365-T369 PolarHBondContact O-N 3.35Å; V365-T369 PolarHBondContact O-OG1 2.96Å; V365-F423 HydrophobicContact CG1-CE1 4.41Å; V365-F423 HydrophobicContact CG1-CZ 3.94Å; V365-P425 HydrophobicContact CG2-CB 4.06Å; V365-P425 HydrophobicContact CG2-CG 3.84Å
366I98.7Very high96.8Very high5 Ų521.1 Ų21.13%0.02612%0.117CC..Hα-helixtrans-63.9-40.4176.2-68.2168.3000111T318 L362 Q364 T369 L370 R462 L465T318-I366 HydrophobicContact CG2-CG2 4.47Å; L362-I366 HydrophobicContact CD1-CD1 3.98Å; L362-I366 HydrophobicContact CD1-CG1 4.33Å; L362-I366 HydrophobicContact CG-CD1 4.01Å; L362-I366 VanDerWaalsContact O-CG1 3.3Å; L362-I366 WeakPolarHBondContact O-CG1 3.39Å; L362-I366 PolarHBondContact O-N 3.37Å; Q364-I366 PolarHBondContact O-N 2.92Å; I366-T369 WeakPolarHBondContact O-CB 3.28Å; I366-T369 PolarHBondContact O-N 3.17Å; I366-L370 HydrophobicContact CG2-CD1 4.11Å; I366-L370 WeakPolarHBondContact O-CG 3.3Å; I366-L370 PolarHBondContact O-N 3.05Å; I366-R462 HydrophobicContact CD1-CB 4.38Å; I366-R462 HydrophobicContact CD1-CG 3.57Å; I366-L465 HydrophobicContact CD1-CD1 3.81Å; I366-L465 HydrophobicContact CG1-CD1 3.58Å
367S98.7Very high96.9Very high19 Ų1921 Ų2113%0.13312%0.117CC..Hα-helixtrans-70-38-177.5-57.70000112.3N363 Q364 V365 L370 R371 F428 W441N363-S367 VanDerWaalsContact O-CB 3.28Å; N363-S367 WeakPolarHBondContact O-CB 3.17Å; N363-S367 PolarHBondContact O-N 2.85Å; N363-S367 PolarHBondContact O-OG 3.46Å; Q364-S367 PolarHBondContact O-N 2.75Å; Q364-S367 VanDerWaalsContact O-N 3.14Å; V365-S367 VanDerWaalsContact C-N 3.33Å; V365-S367 PolarHBondContact O-N 2.87Å; S367-L370 PolarHBondContact O-N 2.62Å; S367-R371 PolarHBondContact O-N 3.4Å; S367-F428 VanDerWaalsContact CB-CG 3.46Å; S367-W441 PolarHBondContact O-NE1 3.46Å
368E98.8Very high97.2Very high0 Ų015.1 Ų15.10%09%0.091CC..Hα-helixtrans-67.3-39173179.963.4176.200111.7Q364 L370 R371 L372 T422 F423 D424 R427 F428Q364-E368 WeakPolarHBondContact O-CB 3.21Å; Q364-E368 PolarHBondContact O-N 2.83Å; E368-L370 VanDerWaalsContact C-N 3.33Å; E368-L370 PolarHBondContact O-N 3.47Å; E368-R371 WeakPolarHBondContact O-CB 3.5Å; E368-R371 PolarHBondContact O-N 3.42Å; E368-R371 IonicContact OE1-CZ 3.24Å; E368-R371 IonicContact OE1-NE 3.93Å; E368-R371 PolarHBondContact OE1-NE 2.87Å; E368-R371 IonicContact OE1-NH2 2.69Å; E368-R371 PolarHBondContact OE1-NH2 3.37Å; E368-R371 WeakPolarHBondContact OE2-CD 3.08Å; E368-R371 IonicContact OE2-CZ 2.69Å; E368-R371 IonicContact OE2-NE 3.33Å; E368-R371 PolarHBondContact OE2-NE 2.79Å; E368-R371 IonicContact OE2-NH2 3.91Å; E368-L372 HydrophobicContact CG-CD1 4.46Å; E368-L372 PolarHBondContact O-N 2.9Å; E368-T422 VanDerWaalsContact OE1-O 3.05Å; E368-F423 HydrophobicContact CB-CE2 4.15Å; E368-F423 HydrophobicContact CB-CZ 4.42Å; E368-F423 HydrophobicContact CG-CD2 3.72Å; E368-F423 HydrophobicContact CG-CE2 3.77Å; E368-F423 HydrophobicContact CG-CG 4.14Å; E368-F423 HydrophobicContact CG-CZ 4.27Å; E368-D424 VanDerWaalsContact CD-O 3.31Å; E368-D424 PolarHBondContact OE1-N 2.81Å; E368-R427 IonicContact OE1-NE 3.42Å; E368-R427 WeakPolarHBondContact OE2-CD 3.4Å; E368-F428 HydrophobicContact CB-CD2 3.99Å; E368-F428 HydrophobicContact CB-CE2 4.14Å; E368-F428 VanDerWaalsContact OE2-CE2 3.25Å; E368-F428 WeakPolarHBondContact OE2-CE2 3.3Å
369T98.8Very high97.4Very high1 Ų113.7 Ų13.71%0.0068%0.076CC..Hα-helixtrans-56.9-48.5171-56.40000110.7C322 V365 I366 R371 L372 Y373C322-T369 HydrophobicContact CB-CG2 3.92Å; V365-T369 WeakPolarHBondContact O-CB 3.4Å; V365-T369 PolarHBondContact O-N 3.35Å; V365-T369 PolarHBondContact O-OG1 2.96Å; I366-T369 WeakPolarHBondContact O-CB 3.28Å; I366-T369 PolarHBondContact O-N 3.17Å; T369-R371 VanDerWaalsContact C-N 3.27Å; T369-R371 PolarHBondContact O-N 2.78Å; T369-L372 PolarHBondContact O-N 3.46Å; T369-Y373 HydrophobicContact CG2-CD2 4.03Å; T369-Y373 WeakPolarHBondContact O-CA 3.47Å; T369-Y373 WeakPolarHBondContact O-CB 3.37Å; T369-Y373 WeakPolarHBondContact O-CD2 3.27Å; T369-Y373 PolarHBondContact O-N 2.85Å
370L98.4Very high97.3Very high7 Ų715.5 Ų15.54%0.0379%0.085CC..Hα-helixtrans-68.1-24.4-179.9-74.5171.1000113.6T318 I366 S367 E368 T374 W441 P443 F444T318-L370 HydrophobicContact CG2-CD2 3.72Å; T318-L370 HydrophobicContact CG2-CG 3.96Å; I366-L370 HydrophobicContact CG2-CD1 4.11Å; I366-L370 WeakPolarHBondContact O-CG 3.3Å; I366-L370 PolarHBondContact O-N 3.05Å; S367-L370 PolarHBondContact O-N 2.62Å; E368-L370 VanDerWaalsContact C-N 3.33Å; E368-L370 PolarHBondContact O-N 3.47Å; L370-T374 PolarHBondContact O-OG1 3.39Å; L370-W441 HydrophobicContact CB-CZ2 4.22Å; L370-W441 HydrophobicContact CD1-CZ2 4.31Å; L370-P443 HydrophobicContact CB-CB 3.76Å; L370-P443 HydrophobicContact CB-CG 4.03Å; L370-P443 HydrophobicContact CD1-CB 4.38Å; L370-P443 HydrophobicContact CD1-CG 4.41Å; L370-P443 HydrophobicContact CD2-CB 4.31Å; L370-P443 HydrophobicContact CG-CB 4.39Å; L370-F444 HydrophobicContact CD1-CE2 3.56Å; L370-F444 HydrophobicContact CD1-CZ 3.71Å
371R98.4Very high97.4Very high0 Ų012.7 Ų12.70%07%0.067CC..Hα-helixtrans-68.2-56.8170.4-173.4-165.466.878.9-4.9109.8S367 E368 T369 Y373 T374 H411 Y417 P420 T422 F428S367-R371 PolarHBondContact O-N 3.4Å; E368-R371 WeakPolarHBondContact O-CB 3.5Å; E368-R371 PolarHBondContact O-N 3.42Å; E368-R371 IonicContact OE1-CZ 3.24Å; E368-R371 IonicContact OE1-NE 3.93Å; E368-R371 PolarHBondContact OE1-NE 2.87Å; E368-R371 IonicContact OE1-NH2 2.69Å; E368-R371 PolarHBondContact OE1-NH2 3.37Å; E368-R371 WeakPolarHBondContact OE2-CD 3.08Å; E368-R371 IonicContact OE2-CZ 2.69Å; E368-R371 IonicContact OE2-NE 3.33Å; E368-R371 PolarHBondContact OE2-NE 2.79Å; E368-R371 IonicContact OE2-NH2 3.91Å; T369-R371 VanDerWaalsContact C-N 3.27Å; T369-R371 PolarHBondContact O-N 2.78Å; R371-Y373 PolarHBondContact O-N 3.47Å; R371-T374 PolarHBondContact O-OG1 3.19Å; R371-H411 HydrophobicContact CG-CB 3.75Å; R371-H411 WeakPolarHBondContact CG-O 3.47Å; R371-H411 PolarHBondContact NH1-O 3.27Å; R371-H411 WeakPolarHBondContact O-CB 3.35Å; R371-H411 PolarHBondContact O-ND1 3.42Å; R371-Y417 VanDerWaalsContact CD-CD1 3.42Å; R371-Y417 VanDerWaalsContact CD-CE1 3.47Å; R371-Y417 HydrophobicContact CG-CE1 4.32Å; R371-P420 VanDerWaalsContact CZ-O 3.26Å; R371-P420 PolarHBondContact NH1-O 3.41Å; R371-P420 PolarHBondContact NH2-O 3.33Å; R371-T422 PolarHBondContact NH2-O 2.57Å; R371-F428 HydrophobicContact CB-CE2 4.16Å; R371-F428 HydrophobicContact CB-CZ 4.07Å
372L97.5Very high97.3Very high3 Ų314.5 Ų14.52%0.0168%0.075CC..Hα-helixtrans-66.2-39.2-176.6-81.7168.6000113E368 T369 R412 P420 F423E368-L372 HydrophobicContact CG-CD1 4.46Å; E368-L372 PolarHBondContact O-N 2.9Å; T369-L372 PolarHBondContact O-N 3.46Å; L372-R412 PolarHBondContact O-NH2 3.22Å; L372-P420 VanDerWaalsContact CD2-O 3.25Å; L372-P420 WeakPolarHBondContact CD2-O 3.43Å; L372-F423 HydrophobicContact CD1-CB 3.82Å; L372-F423 HydrophobicContact CD1-CD2 3.57Å; L372-F423 HydrophobicContact CD1-CG 4.17Å
373Y96.9Very high97.3Very high11 Ų1114.5 Ų14.54%0.0438%0.076CC..SBendtrans-112.669.3-176.7-58.2-89.5000110.7Y321 Y324 E325 T369 R371 L375 L484 Y486 L493Y321-Y373 AromaticContact CD1-CD1 3.58Å; Y321-Y373 HydrophobicContact CD1-CD1 3.58Å; Y321-Y373 AromaticContact CD1-CE1 3.68Å; Y321-Y373 HydrophobicContact CD1-CE1 3.68Å; Y321-Y373 HydrophobicContact CD1-CG 4.19Å; Y321-Y373 AromaticContact CD2-CD1 3.81Å; Y321-Y373 HydrophobicContact CD2-CD1 3.81Å; Y321-Y373 AromaticContact CD2-CG 3.79Å; Y321-Y373 HydrophobicContact CD2-CG 3.79Å; Y321-Y373 HydrophobicContact CE1-CD1 4Å; Y321-Y373 HydrophobicContact CE1-CE1 4.23Å; Y321-Y373 HydrophobicContact CE2-CD1 4.2Å; Y321-Y373 HydrophobicContact CE2-CG 4.5Å; Y321-Y373 AromaticContact CG-CD1 3.49Å; Y321-Y373 HydrophobicContact CG-CD1 3.49Å; Y321-Y373 VanDerWaalsContact CG-CD1 3.49Å; Y321-Y373 HydrophobicContact CG-CD2 4.23Å; Y321-Y373 AromaticContact CG-CE1 3.95Å; Y321-Y373 HydrophobicContact CG-CE1 3.95Å; Y321-Y373 AromaticContact CG-CG 3.62Å; Y321-Y373 HydrophobicContact CG-CG 3.62Å; Y324-Y373 WeakPolarHBondContact CD1-OH 3.27Å; Y324-Y373 VanDerWaalsContact CE1-OH 3.22Å; Y324-Y373 WeakPolarHBondContact CE1-OH 3.4Å; E325-Y373 HydrophobicContact CG-CE2 3.58Å; E325-Y373 VanDerWaalsContact OE1-CE2 3.28Å; E325-Y373 WeakPolarHBondContact OE1-CE2 3.16Å; E325-Y373 PolarHBondContact OE1-OH 3.42Å; T369-Y373 HydrophobicContact CG2-CD2 4.03Å; T369-Y373 WeakPolarHBondContact O-CA 3.47Å; T369-Y373 WeakPolarHBondContact O-CB 3.37Å; T369-Y373 WeakPolarHBondContact O-CD2 3.27Å; T369-Y373 PolarHBondContact O-N 2.85Å; R371-Y373 PolarHBondContact O-N 3.47Å; Y373-L375 PolarHBondContact O-N 3.47Å; Y373-L484 HydrophobicContact CE1-CD1 4.31Å; Y373-Y486 HydrophobicContact CD1-CE1 4.46Å; Y373-Y486 WeakPolarHBondContact CD1-OH 3.38Å; Y373-Y486 WeakPolarHBondContact CE1-OH 3.43Å; Y373-L493 HydrophobicContact CD1-CD2 4.21Å
374T96.6Very high97.3Very high0 Ų015.2 Ų15.20%08%0.079CC..  trans-72.497.8-178.5-50.60000110.2H53 L370 R371 V376 A407 H411H53-T374 WeakPolarHBondContact NE2-CB 3.49Å; L370-T374 PolarHBondContact O-OG1 3.39Å; R371-T374 PolarHBondContact O-OG1 3.19Å; T374-V376 VanDerWaalsContact C-N 3.34Å; T374-V376 WeakPolarHBondContact CG2-O 3.48Å; T374-V376 PolarHBondContact O-N 3.3Å; T374-A407 HydrophobicContact CG2-CB 4.14Å; T374-H411 PolarHBondContact OG1-ND1 2.84Å
375L95.1Very high97.3Very high14 Ų1418.9 Ų18.97%0.07310%0.099CC..SBendtrans-58.9-41.6-171.4-63.6-176.4000113.7T314 T318 Y321 Y373 P377 V492 L493T314-L375 HydrophobicContact CG2-CD1 4.41Å; T314-L375 WeakPolarHBondContact O-CD1 3.36Å; T318-L375 WeakPolarHBondContact OG1-CD1 3.45Å; Y321-L375 HydrophobicContact CD2-CD2 4.06Å; Y321-L375 HydrophobicContact CE2-CD2 3.6Å; Y373-L375 PolarHBondContact O-N 3.47Å; L375-P377 WeakPolarHBondContact O-CD 3.2Å; L375-V492 CarbonylContact O-C 3.32Å; L375-V492 WeakPolarHBondContact O-CA 3.47Å; L375-V492 WeakPolarHBondContact O-CB 3.12Å; L375-L493 HydrophobicContact CD2-CB 4.38Å; L375-L493 PolarHBondContact O-N 2.94Å
376V94.4Very high97.2Very high59 Ų5924 Ų2436%0.35813%0.126SC..SBendtrans-104.4100.9171.9-178.60000107.1T374 H378 V492T374-V376 VanDerWaalsContact C-N 3.34Å; T374-V376 WeakPolarHBondContact CG2-O 3.48Å; T374-V376 PolarHBondContact O-N 3.3Å; V376-H378 WeakPolarHBondContact CG1-O 3.32Å; V376-H378 PolarHBondContact O-N 3.48Å; V376-V492 HydrophobicContact CG2-CG1 4.43Å
377P93.6Very high97.2Very high5 Ų524.7 Ų24.73%0.03213%0.129CC..  trans-68.4-21.2-164.826.1-35.8000113.7M52 L375 A407 C408M52-P377 HydrophobicContact CB-CG 3.99Å; M52-P377 HydrophobicContact CG-CB 4.35Å; M52-P377 HydrophobicContact CG-CG 3.67Å; M52-P377 HydrophobicContact SD-CG 3.51Å; M52-P377 VanDerWaalsContact SD-CG 3.51Å; L375-P377 WeakPolarHBondContact O-CD 3.2Å; P377-A407 PolarHBondContact O-N 2.91Å; P377-A407 VanDerWaalsContact O-N 3.14Å; P377-C408 HydrophobicContact CB-CB 3.88Å; P377-C408 WeakPolarHBondContact O-CB 3.31Å; P377-C408 PolarHBondContact O-N 3.46Å; P377-C408 PolarHBondContact O-SG 3.33Å
378H95.4Very high97.2Very high18 Ų1827.7 Ų27.78%0.08315%0.146CC..  trans-143154.2178.568.5-61.9000112.1M52 F56 V376 E380 I404 I405M52-H378 PolarHBondContact SD-CE1 3.32Å; M52-H378 PolarHBondContact SD-ND1 3.01Å; M52-H378 VanDerWaalsContact SD-ND1 3.37Å; F56-H378 HydrophobicContact CD2-CB 4.14Å; F56-H378 HydrophobicContact CE2-CB 3.71Å; F56-H378 AromaticContact CE2-CG 3.47Å; F56-H378 VanDerWaalsContact CE2-CG 3.47Å; F56-H378 AromaticContact CE2-ND1 3.4Å; F56-H378 WeakPolarHBondContact CE2-ND1 3.22Å; F56-H378 HydrophobicContact CZ-CB 4.37Å; F56-H378 AromaticContact CZ-CG 3.96Å; V376-H378 WeakPolarHBondContact CG1-O 3.32Å; V376-H378 PolarHBondContact O-N 3.48Å; H378-E380 VanDerWaalsContact CD2-CG 3.5Å; H378-E380 WeakPolarHBondContact CD2-CG 3.33Å; H378-E380 IonicContact CD2-OE1 2.76Å; H378-E380 IonicContact CE1-OE1 3.5Å; H378-E380 WeakPolarHBondContact NE2-CG 3.42Å; H378-E380 IonicContact NE2-OE1 2.79Å; H378-E380 PolarHBondContact NE2-OE1 2.82Å; H378-I404 HydrophobicContact CB-CG2 3.98Å; H378-I405 CarbonylContact C-O 3.38Å; H378-I405 WeakPolarHBondContact CA-O 3.38Å; H378-I405 WeakPolarHBondContact CB-O 3.46Å
379L97.1Very high97.1Very high22 Ų2227.9 Ų27.912%0.11515%0.147CC..EExtended strand (participates in β ladder)trans-102.4140.4169.8-48.4176.2000109.4L93 I405 L442L93-L379 HydrophobicContact CD1-CD1 3.98Å; L93-L379 HydrophobicContact CD2-CD1 4.11Å; L379-I405 HydrophobicContact CB-CB 4.2Å; L379-I405 PolarHBondContact N-O 2.93Å; L379-I405 PolarHBondContact O-N 3.31Å; L379-L442 HydrophobicContact CD1-CB 4.33Å; L379-L442 HydrophobicContact CD1-CD1 4.09Å; L379-L442 HydrophobicContact CD1-CD2 4.22Å; L379-L442 HydrophobicContact CD1-CG 4.47Å
380E95.5Very high97Very high37 Ų3731.2 Ų31.217%0.17317%0.169CC..EExtended strand (participates in β ladder)trans-110.2140.8178.7-64.6172157.300110.8Q105 H378 V403Q105-E380 PolarHBondContact NE2-OE2 2.75Å; H378-E380 VanDerWaalsContact CD2-CG 3.5Å; H378-E380 WeakPolarHBondContact CD2-CG 3.33Å; H378-E380 IonicContact CD2-OE1 2.76Å; H378-E380 IonicContact CE1-OE1 3.5Å; H378-E380 WeakPolarHBondContact NE2-CG 3.42Å; H378-E380 IonicContact NE2-OE1 2.79Å; H378-E380 PolarHBondContact NE2-OE1 2.82Å; E380-V403 WeakPolarHBondContact CA-O 3.34Å
381R97.8Very high96.8Very high3 Ų334.7 Ų34.71%0.01121%0.207CC..EExtended strand (participates in β ladder)trans-141.3163.3171.7-63.4-67.7-176.1-86.10.5109.1I92 L93 F100 D102 Q402 V403I92-R381 HydrophobicContact CG2-CB 4.16Å; I92-R381 HydrophobicContact CG2-CG 3.94Å; L93-R381 HydrophobicContact CD2-CG 4.37Å; L93-R381 VanDerWaalsContact CD2-NH2 3.29Å; F100-R381 HydrophobicContact CB-CB 4.15Å; F100-R381 HydrophobicContact CB-CG 4.46Å; F100-R381 HydrophobicContact CD1-CB 4.45Å; F100-R381 WeakPolarHBondContact O-CD 3.21Å; D102-R381 CarbonylContact O-C 3.57Å; D102-R381 VanDerWaalsContact O-CA 3.29Å; D102-R381 WeakPolarHBondContact O-CA 3.04Å; R381-Q402 CarbonylContact O-C 3.36Å; R381-Q402 PolarHBondContact O-OE1 3Å; R381-V403 HydrophobicContact CB-CB 4.05Å; R381-V403 HydrophobicContact CB-CG1 4.44Å; R381-V403 PolarHBondContact N-O 3.48Å; R381-V403 WeakPolarHBondContact O-CB 2.81Å; R381-V403 PolarHBondContact O-N 3.42Å
382K97.3Very high96.6Very high52 Ų5238.2 Ų38.223%0.22622%0.223CC..EExtended strand (participates in β ladder)trans-132.2127.5176.5-177.9-179173.8-167.80110.1D102 L384D102-K382 HydrophobicContact CB-CB 4.27Å; D102-K382 PolarHBondContact O-N 2.86Å; K382-L384 PolarHBondContact O-N 3.29Å
383A98.3Very high96.3Very high1 Ų146.4 Ų46.41%0.00826%0.261CS..  trans-64.8123.2175.400000110.4N99 F100 I397 G400 T401N99-A383 CarbonylContact O-C 3.28Å; F100-A383 HydrophobicContact CD1-CB 4.33Å; F100-A383 HydrophobicContact CE1-CB 3.82Å; A383-I397 HydrophobicContact CB-CG2 3.9Å; A383-G400 WeakPolarHBondContact O-CA 3.26Å; A383-G400 PolarHBondContact O-N 3.03Å; A383-T401 PolarHBondContact N-O 3.45Å
384L97.9Very high96.1Very high50 Ų5055.4 Ų55.426%0.26230%0.301SS..SBendtrans-86.5-28.1178.8-62.4-175000112.2N99 A101 D102 K382 K399N99-L384 WeakPolarHBondContact O-CB 3.19Å; N99-L384 WeakPolarHBondContact O-CG 3.49Å; N99-L384 PolarHBondContact O-N 2.96Å; A101-L384 HydrophobicContact CB-CD1 4.28Å; D102-L384 HydrophobicContact CB-CD2 4.01Å; D102-L384 WeakPolarHBondContact OD2-CD2 3.13Å; K382-L384 PolarHBondContact O-N 3.29Å; L384-K399 VanDerWaalsContact O-CD 3.26Å; L384-K399 WeakPolarHBondContact O-CD 3.39Å; L384-K399 WeakPolarHBondContact O-CE 3.38Å; L384-K399 VanDerWaalsContact O-CG 3.28Å; L384-K399 WeakPolarHBondContact O-CG 3.23Å
385N98.4Very high96.1Very high90 Ų9056 Ų5648%0.48130%0.304SS..SBendtrans-137.9164.5172.7-50.2-74.1000109.4N99 Y387N99-N385 PolarHBondContact ND2-O 3.26Å; N99-N385 WeakPolarHBondContact OD1-CA 3.33Å; N99-N385 VanDerWaalsContact OD1-CB 3.24Å; N99-N385 WeakPolarHBondContact OD1-CB 3.45Å; N99-N385 PolarHBondContact OD1-N 3.07Å; N99-N385 PolarHBondContact OD1-ND2 2.91Å; N99-N385 PolarHBondContact OD1-O 2.99Å; N385-Y387 PolarHBondContact O-N 3.5Å
386D98.4Very high96.3Very high107 Ų10757.6 Ų57.657%0.57231%0.314SS*.  trans-57.9131.2173.5-66-8.2000109.7V396 E398 K399D386-V396 HydrophobicContact CB-CG1 4.1Å; D386-E398 WeakPolarHBondContact OD1-CA 3.25Å; D386-K399 WeakPolarHBondContact OD1-CB 3.32Å; D386-K399 PolarHBondContact OD1-N 2.95Å
387Y98.4Very high96.4Very high19 Ų1954.8 Ų54.88%0.07530%0.297CS..EExtended strand (participates in β ladder)trans-122.4107.6-176.3-177.7-100.3000110L88 N91 D96 F100 N385 V389 P390 V396 I397L88-Y387 HydrophobicContact CD1-CE1 3.84Å; N91-Y387 WeakPolarHBondContact CB-OH 3.37Å; D96-Y387 HydrophobicContact CB-CE2 3.86Å; D96-Y387 VanDerWaalsContact OD2-CE2 3.31Å; D96-Y387 WeakPolarHBondContact OD2-CE2 3.39Å; D96-Y387 PolarHBondContact OD2-OH 2.94Å; F100-Y387 HydrophobicContact CE2-CD1 4.15Å; F100-Y387 AromaticContact CE2-CD2 3.74Å; F100-Y387 HydrophobicContact CE2-CD2 3.74Å; F100-Y387 HydrophobicContact CE2-CE1 4.33Å; F100-Y387 AromaticContact CE2-CE2 3.93Å; F100-Y387 HydrophobicContact CE2-CE2 3.93Å; F100-Y387 AromaticContact CE2-CG 3.84Å; F100-Y387 HydrophobicContact CE2-CG 3.84Å; F100-Y387 AromaticContact CZ-CD1 3.76Å; F100-Y387 HydrophobicContact CZ-CD1 3.76Å; F100-Y387 AromaticContact CZ-CD2 3.95Å; F100-Y387 HydrophobicContact CZ-CD2 3.95Å; F100-Y387 HydrophobicContact CZ-CE1 4.29Å; F100-Y387 HydrophobicContact CZ-CE2 4.46Å; F100-Y387 AromaticContact CZ-CG 3.55Å; F100-Y387 HydrophobicContact CZ-CG 3.55Å; N385-Y387 PolarHBondContact O-N 3.5Å; Y387-V389 HydrophobicContact CD1-CG2 4.28Å; Y387-V389 HydrophobicContact CE1-CG2 4.3Å; Y387-V389 PolarHBondContact O-N 3.19Å; Y387-P390 WeakPolarHBondContact OH-CD 3.12Å; Y387-V396 CarbonylContact O-C 3.6Å; Y387-V396 WeakPolarHBondContact O-CA 3.35Å; Y387-I397 HydrophobicContact CD1-CD1 4.28Å; Y387-I397 PolarHBondContact N-O 3.4Å; Y387-I397 PolarHBondContact O-N 3.21Å
388V98.1Very high96.6Very high82 Ų8257.4 Ų57.450%0.49731%0.309SS..EExtended strand (participates in β ladder)trans-74123170.8-175.80000107.7P390 V396V388-P390 WeakPolarHBondContact O-CD 3.35Å; V388-V396 HydrophobicContact CG2-CG2 4.19Å
389V97.3Very high96.7Very high4 Ų463.1 Ų63.12%0.02433%0.333CS..EExtended strand (participates in β ladder)trans-69.1124.4-178.1176.30000109.8P69 F70 L88 Y387 G391 H392 L395 I397P69-V389 HydrophobicContact CB-CG1 4.2Å; P69-V389 HydrophobicContact CG-CG1 3.73Å; F70-V389 HydrophobicContact CD1-CG2 3.97Å; F70-V389 HydrophobicContact CE1-CG2 3.67Å; L88-V389 HydrophobicContact CD1-CG1 4.08Å; L88-V389 HydrophobicContact CD1-CG2 4.36Å; L88-V389 HydrophobicContact CD2-CG1 4.2Å; L88-V389 HydrophobicContact CD2-CG2 4.22Å; Y387-V389 HydrophobicContact CD1-CG2 4.28Å; Y387-V389 HydrophobicContact CE1-CG2 4.3Å; Y387-V389 PolarHBondContact O-N 3.19Å; V389-G391 PolarHBondContact O-N 2.95Å; V389-H392 HydrophobicContact CB-CB 4.17Å; V389-H392 HydrophobicContact CG1-CB 4.18Å; V389-H392 CarbonylContact O-C 3.36Å; V389-H392 WeakPolarHBondContact O-CA 3.42Å; V389-H392 PolarHBondContact O-N 2.82Å; V389-L395 HydrophobicContact CB-CB 4.34Å; V389-L395 HydrophobicContact CG2-CB 4.34Å; V389-L395 PolarHBondContact N-O 2.91Å; V389-I397 HydrophobicContact CG2-CD1 4.48Å; V389-I397 HydrophobicContact CG2-CG1 4.4Å
390P95.3Very high96.6Very high71 Ų7163.9 Ų63.946%0.46135%0.346SS..THydrogen-bonded Turntrans-54.9130.5177.6-2836.3000111.8Y387 V388 H392Y387-P390 WeakPolarHBondContact OH-CD 3.12Å; V388-P390 WeakPolarHBondContact O-CD 3.35Å; P390-H392 PolarHBondContact O-N 3.13Å
391G94.3Very high96.6Very high81 Ų8162.5 Ų62.584%0.83534%0.341SS*.THydrogen-bonded Turntrans80.2-5-175.500000115.2V389V389-G391 PolarHBondContact O-N 2.95Å
392H94.7Very high96.6Very high74 Ų7464.2 Ų64.234%0.34335%0.348SS..EExtended strand (participates in β ladder)trans-136.871.2-178.6-61.1-93.3000111.5V389 P390 K394 L395V389-H392 HydrophobicContact CB-CB 4.17Å; V389-H392 HydrophobicContact CG1-CB 4.18Å; V389-H392 CarbonylContact O-C 3.36Å; V389-H392 WeakPolarHBondContact O-CA 3.42Å; V389-H392 PolarHBondContact O-N 2.82Å; P390-H392 PolarHBondContact O-N 3.13Å; H392-K394 PolarHBondContact O-N 3.08Å; H392-L395 HydrophobicContact CB-CB 4.02Å; H392-L395 HydrophobicContact CB-CD1 3.81Å; H392-L395 HydrophobicContact CB-CG 4Å; H392-L395 PolarHBondContact O-N 2.9Å
393E92.3Very high96.6Very high175 Ų17561.7 Ų61.782%0.81834%0.338SS*.EExtended strand (participates in β ladder)trans-55.6-26.6-172.1-63.2176.2176.600115.2
394K92.8Very high96.6Very high199 Ų19961.9 Ų61.987%0.86534%0.339SS*.EExtended strand (participates in β ladder)trans-83.8-11.4178.6-62.8-176.9-178.3177.40113.5H392H392-K394 PolarHBondContact O-N 3.08Å
395L96.4Very high96.6Very high14 Ų1459.5 Ų59.57%0.07333%0.326CS..EExtended strand (participates in β ladder)trans-101.5113.1-177.9-60.1-175.6000109.6V31 F68 P69 F70 V389 H392V31-L395 HydrophobicContact CG2-CD2 4.22Å; F68-L395 HydrophobicContact CD1-CD1 3.87Å; F68-L395 HydrophobicContact CD1-CD2 4.18Å; F68-L395 HydrophobicContact CE1-CD1 4.5Å; F68-L395 HydrophobicContact CE1-CD2 4.19Å; P69-L395 VanDerWaalsContact CD-CD1 3.47Å; P69-L395 HydrophobicContact CG-CD1 3.78Å; F70-L395 HydrophobicContact CE1-CB 3.88Å; F70-L395 HydrophobicContact CE1-CD1 4.49Å; F70-L395 HydrophobicContact CZ-CB 4.31Å; V389-L395 HydrophobicContact CB-CB 4.34Å; V389-L395 HydrophobicContact CG2-CB 4.34Å; V389-L395 PolarHBondContact N-O 2.91Å; H392-L395 HydrophobicContact CB-CB 4.02Å; H392-L395 HydrophobicContact CB-CD1 3.81Å; H392-L395 HydrophobicContact CB-CG 4Å; H392-L395 PolarHBondContact O-N 2.9Å
396V97.7Very high96.5Very high46 Ų4655.2 Ų55.228%0.27930%0.303SS..EExtended strand (participates in β ladder)trans-121.7125.5-178.9-175.40000109.8D386 Y387 V388 E398D386-V396 HydrophobicContact CB-CG1 4.1Å; Y387-V396 CarbonylContact O-C 3.6Å; Y387-V396 WeakPolarHBondContact O-CA 3.35Å; V388-V396 HydrophobicContact CG2-CG2 4.19Å; V396-E398 HydrophobicContact CG1-CG 4.4Å; V396-E398 PolarHBondContact O-N 3.05Å
397I98.2Very high96.5Very high0 Ų050.1 Ų50.10%028%0.276CS..EExtended strand (participates in β ladder)trans-86.8101.7165.3-55.7174.7000106.7F70 A81 I83 I92 F100 A383 Y387 V389 T401 V403F70-I397 HydrophobicContact CD1-CD1 4.36Å; F70-I397 HydrophobicContact CD1-CG1 4.24Å; F70-I397 HydrophobicContact CE1-CD1 4.44Å; F70-I397 HydrophobicContact CE1-CG1 3.85Å; F70-I397 HydrophobicContact CZ-CG1 4.08Å; A81-I397 HydrophobicContact CB-CD1 4.25Å; A81-I397 HydrophobicContact CB-CG1 4.24Å; A81-I397 HydrophobicContact CB-CG2 4.35Å; I83-I397 HydrophobicContact CD1-CD1 4.31Å; I92-I397 HydrophobicContact CD1-CD1 4.19Å; F100-I397 HydrophobicContact CE1-CG2 4.5Å; A383-I397 HydrophobicContact CB-CG2 3.9Å; Y387-I397 HydrophobicContact CD1-CD1 4.28Å; Y387-I397 PolarHBondContact N-O 3.4Å; Y387-I397 PolarHBondContact O-N 3.21Å; V389-I397 HydrophobicContact CG2-CD1 4.48Å; V389-I397 HydrophobicContact CG2-CG1 4.4Å; I397-T401 HydrophobicContact CG2-CG2 4.13Å; I397-V403 HydrophobicContact CD1-CG2 4.49Å; I397-V403 HydrophobicContact CG2-CG2 4.04Å
398E97.5Very high96.4Very high60 Ų6049.2 Ų49.228%0.2827%0.272SS..  trans-68.7152.6-175.5-65175.9166.800112.2Y25 R29 D386 V396 G400 T401Y25-E398 WeakPolarHBondContact CE2-OE2 3.31Å; Y25-E398 VanDerWaalsContact CZ-OE2 3.27Å; Y25-E398 VanDerWaalsContact OH-CD 3.27Å; Y25-E398 PolarHBondContact OH-OE2 3.37Å; R29-E398 IonicContact CZ-OE1 3.12Å; R29-E398 IonicContact CZ-OE2 3.29Å; R29-E398 VanDerWaalsContact CZ-OE2 3.29Å; R29-E398 IonicContact NE-OE1 3.55Å; R29-E398 PolarHBondContact NE-OE1 2.9Å; R29-E398 IonicContact NE-OE2 2.75Å; R29-E398 PolarHBondContact NE-OE2 2.59Å; R29-E398 IonicContact NH2-OE1 2.62Å; R29-E398 PolarHBondContact NH2-OE1 3.08Å; R29-E398 IonicContact NH2-OE2 2.7Å; R29-E398 PolarHBondContact NH2-OE2 3.2Å; D386-E398 WeakPolarHBondContact OD1-CA 3.25Å; V396-E398 HydrophobicContact CG1-CG 4.4Å; V396-E398 PolarHBondContact O-N 3.05Å; E398-G400 PolarHBondContact O-N 2.88Å; E398-T401 WeakPolarHBondContact O-CB 3.31Å; E398-T401 PolarHBondContact O-N 3.39Å; E398-T401 PolarHBondContact O-OG1 2.79Å
399K97.6Very high96.4Very high139 Ų13945.3 Ų45.360%0.60425%0.249SC*.THydrogen-bonded Turntrans-48.2130.2173.3175.6168.1-175.4166.70111.9L384 D386 T401L384-K399 VanDerWaalsContact O-CD 3.26Å; L384-K399 WeakPolarHBondContact O-CD 3.39Å; L384-K399 WeakPolarHBondContact O-CE 3.38Å; L384-K399 VanDerWaalsContact O-CG 3.28Å; L384-K399 WeakPolarHBondContact O-CG 3.23Å; D386-K399 WeakPolarHBondContact OD1-CB 3.32Å; D386-K399 PolarHBondContact OD1-N 2.95Å; K399-T401 VanDerWaalsContact C-N 3.27Å; K399-T401 PolarHBondContact O-N 2.97Å
400G94.8Very high96.5Very high37 Ų3745.1 Ų45.138%0.38125%0.248SC..THydrogen-bonded Turntrans85.6-7.9179.100000114.4A383 E398A383-G400 WeakPolarHBondContact O-CA 3.26Å; A383-G400 PolarHBondContact O-N 3.03Å; E398-G400 PolarHBondContact O-N 2.88Å
401T96.3Very high96.6Very high9 Ų941.8 Ų41.86%0.05523%0.226CC..  trans-66.1132.1175-550000109.9Y25 W26 A81 A383 I397 E398 K399Y25-T401 PolarHBondContact OH-OG1 2.88Å; W26-T401 HydrophobicContact CH2-CG2 4.09Å; W26-T401 HydrophobicContact CZ2-CG2 4.22Å; A81-T401 HydrophobicContact CB-CG2 4.38Å; A383-T401 PolarHBondContact N-O 3.45Å; I397-T401 HydrophobicContact CG2-CG2 4.13Å; E398-T401 WeakPolarHBondContact O-CB 3.31Å; E398-T401 PolarHBondContact O-N 3.39Å; E398-T401 PolarHBondContact O-OG1 2.79Å; K399-T401 VanDerWaalsContact C-N 3.27Å; K399-T401 PolarHBondContact O-N 2.97Å
402Q96.2Very high96.7Very high38 Ų3839.6 Ų39.618%0.17819%0.192CC..EExtended strand (participates in β ladder)trans-74.3145.9172-74.6-66.7-4.800109.7A80 A81 R103 R381A80-Q402 CarbonylContact C-O 3.58Å; A80-Q402 WeakPolarHBondContact CA-O 3.42Å; A80-Q402 HydrophobicContact CB-CB 3.94Å; A80-Q402 WeakPolarHBondContact CB-O 3.38Å; A81-Q402 PolarHBondContact N-O 2.91Å; R103-Q402 PolarHBondContact O-NE2 3.42Å; R103-Q402 PolarHBondContact O-OE1 2.76Å; R381-Q402 CarbonylContact O-C 3.36Å; R381-Q402 PolarHBondContact O-OE1 3Å
403V98.1Very high96.8Very high0 Ų036.4 Ų36.40%018%0.178CC..EExtended strand (participates in β ladder)trans-122.9129.1-179173.10000107.7A81 I83 I92 F100 E380 R381 I397 I405A81-V403 HydrophobicContact CB-CG2 4.4Å; A81-V403 CarbonylContact O-C 3.52Å; A81-V403 WeakPolarHBondContact O-CA 3.23Å; I83-V403 HydrophobicContact CD1-CG1 3.8Å; I83-V403 HydrophobicContact CG1-CG1 3.56Å; I92-V403 HydrophobicContact CD1-CG1 3.95Å; I92-V403 HydrophobicContact CG2-CG1 4.29Å; F100-V403 HydrophobicContact CD1-CG2 4.25Å; F100-V403 HydrophobicContact CE1-CG2 4Å; E380-V403 WeakPolarHBondContact CA-O 3.34Å; R381-V403 HydrophobicContact CB-CB 4.05Å; R381-V403 HydrophobicContact CB-CG1 4.44Å; R381-V403 PolarHBondContact N-O 3.48Å; R381-V403 WeakPolarHBondContact O-CB 2.81Å; R381-V403 PolarHBondContact O-N 3.42Å; I397-V403 HydrophobicContact CD1-CG2 4.49Å; I397-V403 HydrophobicContact CG2-CG2 4.04Å; V403-I405 HydrophobicContact CG1-CG1 4.26Å
404I97.4Very high97.1Very high5 Ų532.8 Ų32.83%0.02616%0.161CC..EExtended strand (participates in β ladder)trans-115.4120.9179.2-61.4171.1000107.7F56 F73 A80 A81 F82 I83 H378F56-I404 HydrophobicContact CE1-CG2 4.22Å; F56-I404 HydrophobicContact CZ-CG2 4.19Å; F73-I404 HydrophobicContact CD1-CD1 3.56Å; F73-I404 HydrophobicContact CE1-CD1 3.85Å; F73-I404 HydrophobicContact CG-CD1 4.36Å; A80-I404 HydrophobicContact CB-CD1 3.82Å; A80-I404 HydrophobicContact CB-CG1 4.19Å; A81-I404 PolarHBondContact O-N 2.65Å; F82-I404 HydrophobicContact CD2-CB 4.01Å; F82-I404 HydrophobicContact CD2-CG2 3.67Å; F82-I404 HydrophobicContact CE2-CG2 3.85Å; I83-I404 PolarHBondContact N-O 3.21Å; H378-I404 HydrophobicContact CB-CG2 3.98Å
405I98.4Very high97.2Very high0 Ų028.1 Ų28.10%015%0.145CC..EExtended strand (participates in β ladder)trans-108.6108.8173.7-56.3169.6000107.1I83 A89 I92 L93 H378 L379 V403 A407 Y410 L442I83-I405 HydrophobicContact CB-CG1 4.26Å; I83-I405 HydrophobicContact CG1-CG1 3.95Å; A89-I405 HydrophobicContact CB-CD1 4.37Å; A89-I405 HydrophobicContact CB-CG2 3.94Å; I92-I405 HydrophobicContact CG2-CD1 4.13Å; L93-I405 HydrophobicContact CD1-CD1 3.88Å; L93-I405 HydrophobicContact CD2-CD1 3.6Å; L93-I405 HydrophobicContact CG-CD1 3.57Å; H378-I405 CarbonylContact C-O 3.38Å; H378-I405 WeakPolarHBondContact CA-O 3.38Å; H378-I405 WeakPolarHBondContact CB-O 3.46Å; L379-I405 HydrophobicContact CB-CB 4.2Å; L379-I405 PolarHBondContact N-O 2.93Å; L379-I405 PolarHBondContact O-N 3.31Å; V403-I405 HydrophobicContact CG1-CG1 4.26Å; I405-A407 VanDerWaalsContact C-N 3.33Å; I405-A407 PolarHBondContact O-N 3.46Å; I405-Y410 HydrophobicContact CG2-CD2 4.45Å; I405-Y410 HydrophobicContact CG2-CE2 3.66Å; I405-L442 HydrophobicContact CG2-CD1 3.95Å
406P97.3Very high97.2Very high0 Ų029.5 Ų29.50%015%0.153CC..  trans-8176-171.535.8-38.5000111.5F56 Y60 F82 I83 C408 A409 Y410F56-P406 HydrophobicContact CB-CB 4.45Å; Y60-P406 HydrophobicContact CD2-CG 4.03Å; F82-P406 HydrophobicContact CD1-CG 4.49Å; F82-P406 HydrophobicContact CE1-CB 4.12Å; F82-P406 HydrophobicContact CE1-CG 3.66Å; F82-P406 HydrophobicContact CE2-CB 3.89Å; F82-P406 HydrophobicContact CE2-CG 4.21Å; F82-P406 HydrophobicContact CZ-CB 3.42Å; F82-P406 VanDerWaalsContact CZ-CB 3.42Å; F82-P406 HydrophobicContact CZ-CG 3.5Å; I83-P406 WeakPolarHBondContact O-CD 3.12Å; I83-P406 WeakPolarHBondContact O-CG 3.26Å; P406-C408 PolarHBondContact O-N 3.37Å; P406-A409 HydrophobicContact CB-CB 3.88Å; P406-A409 HydrophobicContact CG-CB 4.21Å; P406-A409 WeakPolarHBondContact O-CA 3.19Å; P406-A409 WeakPolarHBondContact O-CB 3.4Å; P406-A409 PolarHBondContact O-N 2.88Å; P406-Y410 HydrophobicContact CG-CD1 4.16Å; P406-Y410 HydrophobicContact CG-CE1 3.73Å; P406-Y410 PolarHBondContact O-N 2.86Å
407A97.9Very high97.1Very high0 Ų027.4 Ų27.40%014%0.14CC..Hα-helixtrans-50.3-43.9179.600000112.7T374 P377 I405 A409 Y410 H411 L442T374-A407 HydrophobicContact CG2-CB 4.14Å; P377-A407 PolarHBondContact O-N 2.91Å; P377-A407 VanDerWaalsContact O-N 3.14Å; I405-A407 VanDerWaalsContact C-N 3.33Å; I405-A407 PolarHBondContact O-N 3.46Å; A407-A409 PolarHBondContact O-N 2.94Å; A407-Y410 PolarHBondContact O-N 2.84Å; A407-H411 WeakPolarHBondContact O-CB 3.37Å; A407-H411 PolarHBondContact O-CD2 3.45Å; A407-H411 VanDerWaalsContact O-CD2 3.27Å; A407-H411 PolarHBondContact O-N 3.47Å; A407-L442 HydrophobicContact CB-CB 3.87Å; A407-L442 HydrophobicContact CB-CD1 4.49Å
408C96.7Very high97Very high0 Ų031.2 Ų31.20%017%0.165CC..Hα-helixtrans-56-35.9175.458.80000114H53 P377 P406H53-C408 WeakPolarHBondContact CE1-CB 3.43Å; H53-C408 WeakPolarHBondContact ND1-CB 3.49Å; H53-C408 WeakPolarHBondContact NE2-CB 3.05Å; P377-C408 HydrophobicContact CB-CB 3.88Å; P377-C408 WeakPolarHBondContact O-CB 3.31Å; P377-C408 PolarHBondContact O-N 3.46Å; P377-C408 PolarHBondContact O-SG 3.33Å; P406-C408 PolarHBondContact O-N 3.37Å
409A97.4Very high97Very high0 Ų034.2 Ų34.20%018%0.182CC..Hα-helixtrans-81-39.9-178.100000111.2Y57 Y60 P406 A407 H411 R412 D413Y57-A409 HydrophobicContact CD2-CB 4.28Å; Y60-A409 VanDerWaalsContact CB-CB 3.5Å; Y60-A409 HydrophobicContact CD1-CB 3.64Å; Y60-A409 HydrophobicContact CD2-CB 4.26Å; Y60-A409 HydrophobicContact CE1-CB 4.44Å; Y60-A409 HydrophobicContact CG-CB 3.53Å; P406-A409 HydrophobicContact CB-CB 3.88Å; P406-A409 HydrophobicContact CG-CB 4.21Å; P406-A409 WeakPolarHBondContact O-CA 3.19Å; P406-A409 WeakPolarHBondContact O-CB 3.4Å; P406-A409 PolarHBondContact O-N 2.88Å; A407-A409 PolarHBondContact O-N 2.94Å; A409-H411 VanDerWaalsContact C-N 3.26Å; A409-H411 PolarHBondContact O-N 2.97Å; A409-R412 CarbonylContact O-C 3.5Å; A409-R412 PolarHBondContact O-N 3.12Å; A409-D413 PolarHBondContact O-N 3.02Å
410Y98.2Very high97Very high0 Ų028.3 Ų28.30%016%0.158CC..Hα-helixtrans-59.2-41.8173.3-65.90.2000110.9Y60 I83 D85 T86 A89 I405 P406 A407 R412 D413 Y417 L442Y60-Y410 HydrophobicContact CD2-CD1 4.35Å; Y60-Y410 HydrophobicContact CD2-CE1 4.11Å; Y60-Y410 AromaticContact CE2-CD1 3.76Å; Y60-Y410 HydrophobicContact CE2-CD1 3.76Å; Y60-Y410 AromaticContact CE2-CE1 3.53Å; Y60-Y410 HydrophobicContact CE2-CE1 3.53Å; Y60-Y410 AromaticContact CZ-CD1 3.93Å; I83-Y410 WeakPolarHBondContact CG2-OH 3.35Å; I83-Y410 PolarHBondContact O-OH 3.41Å; D85-Y410 PolarHBondContact O-OH 3.43Å; T86-Y410 HydrophobicContact CG2-CD2 4.04Å; T86-Y410 HydrophobicContact CG2-CE2 3.96Å; T86-Y410 HydrophobicContact CG2-CG 4.37Å; A89-Y410 HydrophobicContact CB-CE2 3.97Å; I405-Y410 HydrophobicContact CG2-CD2 4.45Å; I405-Y410 HydrophobicContact CG2-CE2 3.66Å; P406-Y410 HydrophobicContact CG-CD1 4.16Å; P406-Y410 HydrophobicContact CG-CE1 3.73Å; P406-Y410 PolarHBondContact O-N 2.86Å; A407-Y410 PolarHBondContact O-N 2.84Å; Y410-R412 PolarHBondContact O-N 3.19Å; Y410-R412 VanDerWaalsContact O-N 3.14Å; Y410-D413 PolarHBondContact O-N 3.4Å; Y410-Y417 WeakPolarHBondContact O-CD2 3.14Å; Y410-Y417 WeakPolarHBondContact O-CE2 3.39Å; Y410-L442 HydrophobicContact CD2-CD1 3.96Å; Y410-L442 HydrophobicContact CE2-CD1 4.25Å
411H98.3Very high97Very high0 Ų031.7 Ų31.70%016%0.164CC..THydrogen-bonded Turntrans-66.2-14.4178.2-69.1-178.6000114.2R371 T374 A407 A409 L442R371-H411 HydrophobicContact CG-CB 3.75Å; R371-H411 WeakPolarHBondContact CG-O 3.47Å; R371-H411 PolarHBondContact NH1-O 3.27Å; R371-H411 WeakPolarHBondContact O-CB 3.35Å; R371-H411 PolarHBondContact O-ND1 3.42Å; T374-H411 PolarHBondContact OG1-ND1 2.84Å; A407-H411 WeakPolarHBondContact O-CB 3.37Å; A407-H411 PolarHBondContact O-CD2 3.45Å; A407-H411 VanDerWaalsContact O-CD2 3.27Å; A407-H411 PolarHBondContact O-N 3.47Å; A409-H411 VanDerWaalsContact C-N 3.26Å; A409-H411 PolarHBondContact O-N 2.97Å; H411-L442 PolarHBondContact NE2-N 3.14Å
412R96.9Very high97.1Very high35 Ų3535 Ų3513%0.13219%0.185CC..THydrogen-bonded Turntrans-119.912.4179.2-67.3176174.6-108.3-4.3112.6Y57 L372 A409 Y410 E414 P420 E421Y57-R412 HydrophobicContact CD2-CB 3.91Å; Y57-R412 HydrophobicContact CE2-CB 3.44Å; Y57-R412 VanDerWaalsContact CE2-CB 3.44Å; Y57-R412 WeakPolarHBondContact CE2-O 3.29Å; Y57-R412 PolarHBondContact OH-O 2.64Å; L372-R412 PolarHBondContact O-NH2 3.22Å; A409-R412 CarbonylContact O-C 3.5Å; A409-R412 PolarHBondContact O-N 3.12Å; Y410-R412 PolarHBondContact O-N 3.19Å; Y410-R412 VanDerWaalsContact O-N 3.14Å; R412-E414 PolarHBondContact O-N 3.27Å; R412-P420 HydrophobicContact CB-CB 4.35Å; R412-P420 WeakPolarHBondContact O-CB 3.37Å; R412-P420 WeakPolarHBondContact O-CG 3.32Å; R412-E421 IonicContact CZ-OE1 3.64Å; R412-E421 IonicContact CZ-OE2 3.45Å; R412-E421 IonicContact NH1-OE1 2.74Å; R412-E421 PolarHBondContact NH1-OE1 3.48Å; R412-E421 IonicContact NH1-OE2 3.71Å; R412-E421 PolarHBondContact NH1-OE2 2.86Å
413D97.3Very high97.2Very high8 Ų833.8 Ų33.84%0.04318%0.179CC..  trans-73.1121.2173.4-172.4-5.3000109Y60 R64 A409 Y410 D415 L416 Y417Y60-D413 HydrophobicContact CE1-CB 4.05Å; Y60-D413 PolarHBondContact OH-OD2 3.36Å; R64-D413 IonicContact CZ-OD1 2.64Å; R64-D413 IonicContact NE-OD1 3.85Å; R64-D413 PolarHBondContact NE-OD1 3.31Å; R64-D413 IonicContact NE-OD2 2.64Å; R64-D413 IonicContact NH1-OD1 2.78Å; R64-D413 PolarHBondContact NH1-OD1 3.42Å; R64-D413 IonicContact NH2-OD1 2.71Å; R64-D413 PolarHBondContact NH2-OD1 3.21Å; A409-D413 PolarHBondContact O-N 3.02Å; Y410-D413 PolarHBondContact O-N 3.4Å; D413-D415 PolarHBondContact O-N 3.06Å; D413-D415 WeakPolarHBondContact OD1-CB 3.26Å; D413-D415 PolarHBondContact OD1-N 3.45Å; D413-L416 HydrophobicContact CB-CB 4.24Å; D413-L416 HydrophobicContact CB-CD1 4.09Å; D413-L416 HydrophobicContact CB-CG 4.06Å; D413-L416 PolarHBondContact O-N 2.87Å; D413-Y417 PolarHBondContact O-N 3.07Å
414E96.7Very high97.2Very high99 Ų9936.1 Ų36.146%0.46319%0.191SC..THydrogen-bonded Turntrans-64.9-24.417867.1-170.9169.800112.8R64 K65 R412 L416 Y417 P420R64-E414 IonicContact CZ-OE1 3.53Å; R64-E414 IonicContact NH1-OE1 3.56Å; R64-E414 IonicContact NH2-OE1 2.81Å; R64-E414 PolarHBondContact NH2-OE1 3.42Å; K65-E414 IonicContact NZ-OE1 3.77Å; R412-E414 PolarHBondContact O-N 3.27Å; E414-L416 VanDerWaalsContact C-N 3.31Å; E414-Y417 CarbonylContact O-C 3.4Å; E414-P420 HydrophobicContact CB-CG 4.31Å
415D95.3Very high97.3Very high101 Ų10136 Ų3654%0.5419%0.19SC..THydrogen-bonded Turntrans-73.7-27.2177.7-61.5-37.8000110.8R64 K65 D413R64-D415 IonicContact CZ-OD2 3.72Å; R64-D415 IonicContact NE-OD2 3.17Å; R64-D415 PolarHBondContact NE-OD2 3.35Å; R64-D415 IonicContact NH2-OD1 2.65Å; R64-D415 IonicContact NH2-OD2 3.76Å; R64-D415 PolarHBondContact NH2-OD2 2.95Å; K65-D415 WeakPolarHBondContact CE-OD2 3.38Å; K65-D415 IonicContact NZ-OD2 2.64Å; D413-D415 PolarHBondContact O-N 3.06Å; D413-D415 WeakPolarHBondContact OD1-CB 3.26Å; D413-D415 PolarHBondContact OD1-N 3.45Å
416L96.3Very high97.3Very high43 Ų4338.9 Ų38.923%0.22520%0.204CC..THydrogen-bonded Turntrans-95.5-36.4176.2-58.3179.8000112.5T86 D413 E414 E440T86-L416 HydrophobicContact CG2-CD1 4.08Å; D413-L416 HydrophobicContact CB-CB 4.24Å; D413-L416 HydrophobicContact CB-CD1 4.09Å; D413-L416 HydrophobicContact CB-CG 4.06Å; D413-L416 PolarHBondContact O-N 2.87Å; E414-L416 VanDerWaalsContact C-N 3.31Å; L416-E440 HydrophobicContact CD1-CB 4.24Å; L416-E440 HydrophobicContact CD1-CG 4.11Å; L416-E440 HydrophobicContact CD2-CG 4.03Å
417Y97.1Very high97.3Very high2 Ų239.9 Ų39.91%0.00821%0.208CC..SBendtrans-133.689.6-175.4-59.6-80.2000110.1R371 Y410 D413 E414 N419 P420 E440R371-Y417 VanDerWaalsContact CD-CD1 3.42Å; R371-Y417 VanDerWaalsContact CD-CE1 3.47Å; R371-Y417 HydrophobicContact CG-CE1 4.32Å; Y410-Y417 WeakPolarHBondContact O-CD2 3.14Å; Y410-Y417 WeakPolarHBondContact O-CE2 3.39Å; D413-Y417 PolarHBondContact O-N 3.07Å; E414-Y417 CarbonylContact O-C 3.4Å; Y417-N419 PolarHBondContact O-N 2.83Å; Y417-P420 WeakPolarHBondContact O-CA 3.35Å; Y417-P420 WeakPolarHBondContact O-CB 2.83Å; Y417-P420 VanDerWaalsContact O-CD 3.29Å; Y417-P420 WeakPolarHBondContact O-CD 3.44Å; Y417-E440 WeakPolarHBondContact CE2-O 3.48Å; Y417-E440 PolarHBondContact OH-O 3.19Å
418P96.2Very high97.3Very high80 Ų8040.5 Ų40.552%0.51921%0.21SC..SBendtrans-57.8134.7-179.9-26.334.5000111.9R427P418-R427 PolarHBondContact O-NH1 3.06Å; P418-R427 PolarHBondContact O-NH2 3.13Å
419N97.1Very high97.3Very high123 Ų12341 Ų4166%0.65821%0.214SC*.SBendtrans54.960.9-168.9-53.7-53.3000112.3Y417 E421 T422 R427Y417-N419 PolarHBondContact O-N 2.83Å; N419-E421 PolarHBondContact O-N 3.02Å; N419-T422 PolarHBondContact O-N 3.44Å; N419-T422 VanDerWaalsContact O-N 3.08Å; N419-R427 PolarHBondContact O-NH2 3.48Å
420P96.9Very high97.3Very high15 Ų1544.5 Ų44.510%0.09724%0.237CC..THydrogen-bonded Turntrans-65.5-16.8-16624.2-33.7000114.3R371 L372 R412 E414 Y417R371-P420 VanDerWaalsContact CZ-O 3.26Å; R371-P420 PolarHBondContact NH1-O 3.41Å; R371-P420 PolarHBondContact NH2-O 3.33Å; L372-P420 VanDerWaalsContact CD2-O 3.25Å; L372-P420 WeakPolarHBondContact CD2-O 3.43Å; R412-P420 HydrophobicContact CB-CB 4.35Å; R412-P420 WeakPolarHBondContact O-CB 3.37Å; R412-P420 WeakPolarHBondContact O-CG 3.32Å; E414-P420 HydrophobicContact CB-CG 4.31Å; Y417-P420 WeakPolarHBondContact O-CA 3.35Å; Y417-P420 WeakPolarHBondContact O-CB 2.83Å; Y417-P420 VanDerWaalsContact O-CD 3.29Å; Y417-P420 WeakPolarHBondContact O-CD 3.44Å
421E95.7Very high97.2Very high107 Ų10750.8 Ų50.850%0.527%0.266SS..THydrogen-bonded Turntrans-85.7-12179.4-61.5-58.9138.200113.3R412 N419R412-E421 IonicContact CZ-OE1 3.64Å; R412-E421 IonicContact CZ-OE2 3.45Å; R412-E421 IonicContact NH1-OE1 2.74Å; R412-E421 PolarHBondContact NH1-OE1 3.48Å; R412-E421 IonicContact NH1-OE2 3.71Å; R412-E421 PolarHBondContact NH1-OE2 2.86Å; N419-E421 PolarHBondContact O-N 3.02Å
422T97.5Very high97.2Very high80 Ų8055.5 Ų55.549%0.49129%0.287SS..SBendtrans-82.8130179.3-55.90000110.8E368 R371 N419 D424E368-T422 VanDerWaalsContact OE1-O 3.05Å; R371-T422 PolarHBondContact NH2-O 2.57Å; N419-T422 PolarHBondContact O-N 3.44Å; N419-T422 VanDerWaalsContact O-N 3.08Å; T422-D424 PolarHBondContact O-N 3.47Å; T422-D424 VanDerWaalsContact O-N 3.17Å
423F98.6Very high97.2Very high12 Ų1257.1 Ų57.15%0.05330%0.301CS..  trans-72.998.6171-171.7-96.1000110.2E325 I332 V365 E368 L372 P425E325-F423 HydrophobicContact CB-CD1 4.18Å; E325-F423 HydrophobicContact CB-CD2 3.7Å; E325-F423 HydrophobicContact CB-CE1 4.15Å; E325-F423 HydrophobicContact CB-CE2 3.72Å; E325-F423 HydrophobicContact CB-CG 3.98Å; E325-F423 HydrophobicContact CB-CZ 3.95Å; E325-F423 HydrophobicContact CG-CD2 3.49Å; E325-F423 VanDerWaalsContact CG-CD2 3.49Å; E325-F423 HydrophobicContact CG-CE2 3.77Å; E325-F423 HydrophobicContact CG-CG 4.07Å; E325-F423 HydrophobicContact CG-CZ 4.5Å; I332-F423 HydrophobicContact CD1-CD1 3.74Å; I332-F423 HydrophobicContact CD1-CE1 4.15Å; I332-F423 HydrophobicContact CG2-CE1 4.21Å; V365-F423 HydrophobicContact CG1-CE1 4.41Å; V365-F423 HydrophobicContact CG1-CZ 3.94Å; E368-F423 HydrophobicContact CB-CE2 4.15Å; E368-F423 HydrophobicContact CB-CZ 4.42Å; E368-F423 HydrophobicContact CG-CD2 3.72Å; E368-F423 HydrophobicContact CG-CE2 3.77Å; E368-F423 HydrophobicContact CG-CG 4.14Å; E368-F423 HydrophobicContact CG-CZ 4.27Å; L372-F423 HydrophobicContact CD1-CB 3.82Å; L372-F423 HydrophobicContact CD1-CD2 3.57Å; L372-F423 HydrophobicContact CD1-CG 4.17Å; F423-P425 HydrophobicContact CD1-CG 4.32Å; F423-P425 HydrophobicContact CE1-CG 3.84Å; F423-P425 HydrophobicContact CZ-CG 4.46Å
424D98.4Very high97.2Very high48 Ų4861 Ų6126%0.25733%0.333SS..  trans-127.297.4-178.7174.719.4000111.5E368 T422 E426 R427E368-D424 VanDerWaalsContact CD-O 3.31Å; E368-D424 PolarHBondContact OE1-N 2.81Å; T422-D424 PolarHBondContact O-N 3.47Å; T422-D424 VanDerWaalsContact O-N 3.17Å; D424-E426 PolarHBondContact O-N 2.72Å; D424-E426 VanDerWaalsContact OD1-CB 3.23Å; D424-E426 WeakPolarHBondContact OD1-CB 3.38Å; D424-E426 PolarHBondContact OD1-N 2.72Å; D424-R427 HydrophobicContact CB-CG 4.16Å; D424-R427 WeakPolarHBondContact O-CB 3.36Å; D424-R427 VanDerWaalsContact O-CG 3.31Å; D424-R427 WeakPolarHBondContact O-CG 3.47Å; D424-R427 PolarHBondContact O-N 2.92Å
425P98.6Very high97.1Very high2 Ų260.5 Ų60.51%0.01335%0.346CS..G310 helixtrans-57.2-27.1175.4-26.935.9000114I332 Y361 Q364 V365 F423 R427 F428I332-P425 HydrophobicContact CD1-CG 4.21Å; I332-P425 HydrophobicContact CG2-CG 3.89Å; Y361-P425 HydrophobicContact CE2-CB 3.86Å; Q364-P425 HydrophobicContact CB-CB 3.98Å; Q364-P425 WeakPolarHBondContact CB-O 3.43Å; V365-P425 HydrophobicContact CG2-CB 4.06Å; V365-P425 HydrophobicContact CG2-CG 3.84Å; F423-P425 HydrophobicContact CD1-CG 4.32Å; F423-P425 HydrophobicContact CE1-CG 3.84Å; F423-P425 HydrophobicContact CZ-CG 4.46Å; P425-R427 PolarHBondContact O-N 2.79Å; P425-F428 PolarHBondContact O-N 2.76Å
426E98Very high97.1Very high62 Ų6257.6 Ų57.629%0.2933%0.328SS..G310 helixtrans-65.9-13.2-178.9-63.8-61.9145.700112.7R335 D424 F428 S429 K432R335-E426 IonicContact CZ-OE1 3.19Å; R335-E426 IonicContact NH1-OE1 3.11Å; R335-E426 PolarHBondContact NH1-OE1 3.47Å; R335-E426 IonicContact NH2-OE1 3.62Å; R335-E426 PolarHBondContact NH2-OE1 3.06Å; D424-E426 PolarHBondContact O-N 2.72Å; D424-E426 VanDerWaalsContact OD1-CB 3.23Å; D424-E426 WeakPolarHBondContact OD1-CB 3.38Å; D424-E426 PolarHBondContact OD1-N 2.72Å; E426-F428 PolarHBondContact O-N 3.07Å; E426-S429 PolarHBondContact O-N 2.98Å; E426-K432 VanDerWaalsContact O-CD 3.28Å; E426-K432 WeakPolarHBondContact O-CD 2.92Å; E426-K432 WeakPolarHBondContact O-CE 3.46Å; E426-K432 PolarHBondContact O-NZ 2.66Å
427R97.8Very high97.2Very high21 Ų2159.3 Ų59.38%0.07934%0.335CS..G310 helixtrans-60.3-22.9168.1-65.2178.2-166.3-72.1-3.8112.4E368 P418 N419 D424 P425 K432 R436E368-R427 IonicContact OE1-NE 3.42Å; E368-R427 WeakPolarHBondContact OE2-CD 3.4Å; P418-R427 PolarHBondContact O-NH1 3.06Å; P418-R427 PolarHBondContact O-NH2 3.13Å; N419-R427 PolarHBondContact O-NH2 3.48Å; D424-R427 HydrophobicContact CB-CG 4.16Å; D424-R427 WeakPolarHBondContact O-CB 3.36Å; D424-R427 VanDerWaalsContact O-CG 3.31Å; D424-R427 WeakPolarHBondContact O-CG 3.47Å; D424-R427 PolarHBondContact O-N 2.92Å; P425-R427 PolarHBondContact O-N 2.79Å; R427-K432 WeakPolarHBondContact O-CB 3.25Å; R427-R436 PolarHBondContact O-NH2 3.46Å
428F98.4Very high97.1Very high12 Ų1262.1 Ų62.15%0.05335%0.354CS..G310 helixtrans-108.320-176.7-69.9-86.4000113Q364 S367 E368 R371 P425 E426 V433 W441Q364-F428 HydrophobicContact CB-CB 4.17Å; Q364-F428 HydrophobicContact CG-CB 4.09Å; Q364-F428 WeakPolarHBondContact CG-O 3.49Å; S367-F428 VanDerWaalsContact CB-CG 3.46Å; E368-F428 HydrophobicContact CB-CD2 3.99Å; E368-F428 HydrophobicContact CB-CE2 4.14Å; E368-F428 VanDerWaalsContact OE2-CE2 3.25Å; E368-F428 WeakPolarHBondContact OE2-CE2 3.3Å; R371-F428 HydrophobicContact CB-CE2 4.16Å; R371-F428 HydrophobicContact CB-CZ 4.07Å; P425-F428 PolarHBondContact O-N 2.76Å; E426-F428 PolarHBondContact O-N 3.07Å; F428-V433 HydrophobicContact CB-CG2 4.23Å; F428-V433 HydrophobicContact CD1-CG2 4Å; F428-V433 WeakPolarHBondContact O-CG2 3.41Å; F428-W441 AromaticContact CE1-CD1 3.48Å; F428-W441 VanDerWaalsContact CE1-CD1 3.48Å; F428-W441 AromaticContact CE1-CD2 3.86Å; F428-W441 HydrophobicContact CE1-CD2 3.86Å; F428-W441 AromaticContact CE1-CE2 3.56Å; F428-W441 AromaticContact CE1-CG 3.77Å; F428-W441 HydrophobicContact CE1-CG 3.77Å; F428-W441 HydrophobicContact CE1-CZ2 4.24Å; F428-W441 AromaticContact CE1-NE1 3.31Å; F428-W441 VanDerWaalsContact CE1-NE1 3.31Å; F428-W441 AromaticContact CZ-CD1 3.34Å; F428-W441 HydrophobicContact CZ-CD2 4.46Å; F428-W441 AromaticContact CZ-CE2 3.95Å; F428-W441 HydrophobicContact CZ-CG 4.08Å; F428-W441 AromaticContact CZ-NE1 3.21Å
429S97.7Very high97.1Very high12 Ų1258.3 Ų58.38%0.08433%0.33CS..  trans-53.6147.5168.294.50000110.7E426 E431 K432 V433E426-S429 PolarHBondContact O-N 2.98Å; S429-E431 WeakPolarHBondContact CB-OE2 3.48Å; S429-E431 PolarHBondContact O-N 2.82Å; S429-E431 VanDerWaalsContact O-N 3.1Å; S429-E431 PolarHBondContact OG-OE2 3.4Å; S429-K432 PolarHBondContact O-N 2.61Å; S429-K432 VanDerWaalsContact O-N 3.08Å; S429-K432 PolarHBondContact OG-N 2.86Å; S429-V433 WeakPolarHBondContact O-CG2 3.35Å; S429-V433 PolarHBondContact O-N 3.04Å
430P96.5Very high97.1Very high73 Ų7354.2 Ų54.247%0.47431%0.307SS..Hα-helixtrans-50.9-38.4-178.9-28.536.2000113.3T360 A434T360-P430 HydrophobicContact CG2-CG 4.37Å; P430-A434 VanDerWaalsContact O-CB 3.3Å; P430-A434 WeakPolarHBondContact O-CB 3.4Å; P430-A434 PolarHBondContact O-N 2.89Å
431E96.9Very high97.2Very high131 Ų13156 Ų5661%0.61231%0.311SS*.Hα-helixtrans-67.8-47.2179.9-53.371-151.400111.4S429 A434 A435S429-E431 WeakPolarHBondContact CB-OE2 3.48Å; S429-E431 PolarHBondContact O-N 2.82Å; S429-E431 VanDerWaalsContact O-N 3.1Å; S429-E431 PolarHBondContact OG-OE2 3.4Å; E431-A434 PolarHBondContact O-N 3.17Å; E431-A435 WeakPolarHBondContact O-CB 3.47Å; E431-A435 PolarHBondContact O-N 3.05Å
432K97.1Very high97.3Very high99 Ų9951 Ų5143%0.4329%0.288SS..Hα-helixtrans-67.9-35.8178.6-69.6-170.9-164.9156.50112.1E426 R427 S429 A435 R436E426-K432 VanDerWaalsContact O-CD 3.28Å; E426-K432 WeakPolarHBondContact O-CD 2.92Å; E426-K432 WeakPolarHBondContact O-CE 3.46Å; E426-K432 PolarHBondContact O-NZ 2.66Å; R427-K432 WeakPolarHBondContact O-CB 3.25Å; S429-K432 PolarHBondContact O-N 2.61Å; S429-K432 VanDerWaalsContact O-N 3.08Å; S429-K432 PolarHBondContact OG-N 2.86Å; K432-A435 PolarHBondContact O-N 2.66Å; K432-R436 WeakPolarHBondContact O-CB 3.28Å; K432-R436 PolarHBondContact O-N 3.45Å
433V97Very high97.3Very high70 Ų7048.2 Ų48.242%0.42427%0.272SS..Hα-helixtrans-66.1-42.3174.6173.90000110.8F428 S429 A435 R436F428-V433 HydrophobicContact CB-CG2 4.23Å; F428-V433 HydrophobicContact CD1-CG2 4Å; F428-V433 WeakPolarHBondContact O-CG2 3.41Å; S429-V433 WeakPolarHBondContact O-CG2 3.35Å; S429-V433 PolarHBondContact O-N 3.04Å; V433-A435 VanDerWaalsContact C-N 3.31Å; V433-A435 PolarHBondContact O-N 3.11Å; V433-R436 PolarHBondContact O-N 3.11Å
434A96.6Very high97.2Very high88 Ų8849.5 Ų49.573%0.72728%0.277SS*.Hα-helixtrans-66.4-32.1178.500000113.1P430 E431P430-A434 VanDerWaalsContact O-CB 3.3Å; P430-A434 WeakPolarHBondContact O-CB 3.4Å; P430-A434 PolarHBondContact O-N 2.89Å; E431-A434 PolarHBondContact O-N 3.17Å
435A96.3Very high97.2Very high89 Ų8947.9 Ų47.974%0.73627%0.272SS*.Hα-helixtrans-80.4-15.2176.700000113.9E431 K432 V433E431-A435 WeakPolarHBondContact O-CB 3.47Å; E431-A435 PolarHBondContact O-N 3.05Å; K432-A435 PolarHBondContact O-N 2.66Å; V433-A435 VanDerWaalsContact C-N 3.31Å; V433-A435 PolarHBondContact O-N 3.11Å
436R95.4Very high97.1Very high41 Ų4149.3 Ų49.316%0.15528%0.279CS..SBendtrans-86141.7-176.1-168.4-174.6-70.5132.711111.4R427 K432 V433 E440R427-R436 PolarHBondContact O-NH2 3.46Å; K432-R436 WeakPolarHBondContact O-CB 3.28Å; K432-R436 PolarHBondContact O-N 3.45Å; V433-R436 PolarHBondContact O-N 3.11Å; R436-E440 HydrophobicContact CG-CB 3.89Å; R436-E440 WeakPolarHBondContact CG-OE2 3.26Å
437E96.5Very high97.1Very high79 Ų7947 Ų4737%0.36927%0.272SS..  trans-69.6134.6166.9-74-69.1178.700111K90 V439 E440K90-E437 IonicContact NZ-OE1 2.88Å; K90-E437 PolarHBondContact NZ-OE1 3.39Å; K90-E437 VanDerWaalsContact NZ-OE1 3.12Å; K90-E437 IonicContact NZ-OE2 3.29Å; K90-E437 PolarHBondContact NZ-OE2 3.24Å; E437-V439 HydrophobicContact CB-CG2 4.39Å; E437-V439 PolarHBondContact O-N 3.3Å; E437-E440 HydrophobicContact CB-CG 4.01Å; E437-E440 WeakPolarHBondContact O-CB 3.38Å; E437-E440 PolarHBondContact O-N 3Å
438S95Very high97.1Very high60 Ų6049.1 Ų49.142%0.4229%0.288SS..G310 helixtrans-57.7-31.8-173.762.80000113.2E440 W441 D446S438-E440 VanDerWaalsContact C-N 3.26Å; S438-E440 PolarHBondContact O-N 2.81Å; S438-W441 CarbonylContact O-C 3.52Å; S438-W441 PolarHBondContact O-N 3.46Å; S438-D446 WeakPolarHBondContact CB-OD2 3.17Å; S438-D446 PolarHBondContact OG-OD2 3.32Å
439V97Very high97Very high1 Ų148.7 Ų48.71%0.00629%0.287CS..G310 helixtrans-76.6-6.2179.9-65.30000115.1K90 L93 I94 E437 W441 L442 D446K90-V439 HydrophobicContact CB-CG1 3.95Å; K90-V439 HydrophobicContact CB-CG2 3.91Å; K90-V439 HydrophobicContact CG-CG1 4.33Å; L93-V439 HydrophobicContact CD1-CG1 4.24Å; I94-V439 HydrophobicContact CD1-CG1 4.16Å; E437-V439 HydrophobicContact CB-CG2 4.39Å; E437-V439 PolarHBondContact O-N 3.3Å; V439-W441 VanDerWaalsContact C-N 3.26Å; V439-L442 HydrophobicContact CB-CD2 4.37Å; V439-L442 HydrophobicContact CG1-CD2 4.43Å; V439-L442 VanDerWaalsContact O-CD1 3.27Å; V439-L442 WeakPolarHBondContact O-CD1 3.34Å; V439-L442 VanDerWaalsContact O-CG 3.27Å; V439-L442 WeakPolarHBondContact O-CG 3.41Å; V439-D446 HydrophobicContact CG1-CB 4.49Å
440E97.5Very high97Very high37 Ų3750.1 Ų50.117%0.17329%0.293CS..G310 helixtrans-81.2-13.1171.7-62.3172.5-178.700111.1T86 L416 Y417 R436 E437 S438T86-E440 HydrophobicContact CG2-CG 4.35Å; L416-E440 HydrophobicContact CD1-CB 4.24Å; L416-E440 HydrophobicContact CD1-CG 4.11Å; L416-E440 HydrophobicContact CD2-CG 4.03Å; Y417-E440 WeakPolarHBondContact CE2-O 3.48Å; Y417-E440 PolarHBondContact OH-O 3.19Å; R436-E440 HydrophobicContact CG-CB 3.89Å; R436-E440 WeakPolarHBondContact CG-OE2 3.26Å; E437-E440 HydrophobicContact CB-CG 4.01Å; E437-E440 WeakPolarHBondContact O-CB 3.38Å; E437-E440 PolarHBondContact O-N 3Å; S438-E440 VanDerWaalsContact C-N 3.26Å; S438-E440 PolarHBondContact O-N 2.81Å
441W98.1Very high97.1Very high51 Ų5149.2 Ų49.219%0.19329%0.288CS..  trans-133.296.1174.6-171.474.2000111.3S367 L370 F428 S438 V439 P443 F444S367-W441 PolarHBondContact O-NE1 3.46Å; L370-W441 HydrophobicContact CB-CZ2 4.22Å; L370-W441 HydrophobicContact CD1-CZ2 4.31Å; F428-W441 AromaticContact CE1-CD1 3.48Å; F428-W441 VanDerWaalsContact CE1-CD1 3.48Å; F428-W441 AromaticContact CE1-CD2 3.86Å; F428-W441 HydrophobicContact CE1-CD2 3.86Å; F428-W441 AromaticContact CE1-CE2 3.56Å; F428-W441 AromaticContact CE1-CG 3.77Å; F428-W441 HydrophobicContact CE1-CG 3.77Å; F428-W441 HydrophobicContact CE1-CZ2 4.24Å; F428-W441 AromaticContact CE1-NE1 3.31Å; F428-W441 VanDerWaalsContact CE1-NE1 3.31Å; F428-W441 AromaticContact CZ-CD1 3.34Å; F428-W441 HydrophobicContact CZ-CD2 4.46Å; F428-W441 AromaticContact CZ-CE2 3.95Å; F428-W441 HydrophobicContact CZ-CG 4.08Å; F428-W441 AromaticContact CZ-NE1 3.21Å; S438-W441 CarbonylContact O-C 3.52Å; S438-W441 PolarHBondContact O-N 3.46Å; V439-W441 VanDerWaalsContact C-N 3.26Å; W441-P443 HydrophobicContact CD2-CG 3.65Å; W441-P443 HydrophobicContact CE3-CG 3.9Å; W441-P443 HydrophobicContact CG-CG 4.38Å; W441-P443 HydrophobicContact CH2-CG 3.58Å; W441-P443 HydrophobicContact CZ2-CG 3.29Å; W441-P443 HydrophobicContact CZ3-CG 3.86Å; W441-P443 WeakPolarHBondContact O-CD 3.29Å; W441-F444 HydrophobicContact CH2-CD2 4.34Å; W441-F444 HydrophobicContact CH2-CE2 4.28Å
442L98.1Very high97.1Very high2 Ų244.2 Ų44.21%0.0127%0.265CS..  trans-111.931.9-170.5-67.2174.3000116.2L93 L379 I405 A407 Y410 H411 V439 F444 G445 D446L93-L442 HydrophobicContact CD1-CD1 4.26Å; L93-L442 HydrophobicContact CD1-CD2 3.91Å; L379-L442 HydrophobicContact CD1-CB 4.33Å; L379-L442 HydrophobicContact CD1-CD1 4.09Å; L379-L442 HydrophobicContact CD1-CD2 4.22Å; L379-L442 HydrophobicContact CD1-CG 4.47Å; I405-L442 HydrophobicContact CG2-CD1 3.95Å; A407-L442 HydrophobicContact CB-CB 3.87Å; A407-L442 HydrophobicContact CB-CD1 4.49Å; Y410-L442 HydrophobicContact CD2-CD1 3.96Å; Y410-L442 HydrophobicContact CE2-CD1 4.25Å; H411-L442 PolarHBondContact NE2-N 3.14Å; V439-L442 HydrophobicContact CB-CD2 4.37Å; V439-L442 HydrophobicContact CG1-CD2 4.43Å; V439-L442 VanDerWaalsContact O-CD1 3.27Å; V439-L442 WeakPolarHBondContact O-CD1 3.34Å; V439-L442 VanDerWaalsContact O-CG 3.27Å; V439-L442 WeakPolarHBondContact O-CG 3.41Å; L442-F444 PolarHBondContact O-N 3.47Å; L442-F444 VanDerWaalsContact O-N 3.14Å; L442-G445 PolarHBondContact O-N 3.3Å; L442-D446 HydrophobicContact CD2-CB 3.74Å
443P97.1Very high97Very high23 Ų2340.3 Ų40.315%0.14925%0.253CS..THydrogen-bonded Turntrans-66.9-20.6-177.928.6-33.7000113.6L370 W441L370-P443 HydrophobicContact CB-CB 3.76Å; L370-P443 HydrophobicContact CB-CG 4.03Å; L370-P443 HydrophobicContact CD1-CB 4.38Å; L370-P443 HydrophobicContact CD1-CG 4.41Å; L370-P443 HydrophobicContact CD2-CB 4.31Å; L370-P443 HydrophobicContact CG-CB 4.39Å; W441-P443 HydrophobicContact CD2-CG 3.65Å; W441-P443 HydrophobicContact CE3-CG 3.9Å; W441-P443 HydrophobicContact CG-CG 4.38Å; W441-P443 HydrophobicContact CH2-CG 3.58Å; W441-P443 HydrophobicContact CZ2-CG 3.29Å; W441-P443 HydrophobicContact CZ3-CG 3.86Å; W441-P443 WeakPolarHBondContact O-CD 3.29Å
444F97.8Very high96.9Very high39 Ų3939.5 Ų39.517%0.17125%0.246CC..THydrogen-bonded Turntrans-109.47.6173.3-63.3-73000112.7L370 W441 L442 C451 M454 Q458L370-F444 HydrophobicContact CD1-CE2 3.56Å; L370-F444 HydrophobicContact CD1-CZ 3.71Å; W441-F444 HydrophobicContact CH2-CD2 4.34Å; W441-F444 HydrophobicContact CH2-CE2 4.28Å; L442-F444 PolarHBondContact O-N 3.47Å; L442-F444 VanDerWaalsContact O-N 3.14Å; F444-C451 HydrophobicContact CB-CB 3.85Å; F444-C451 HydrophobicContact CD1-CB 3.87Å; F444-C451 HydrophobicContact CG-CB 4.34Å; F444-C451 WeakPolarHBondContact O-CB 3.48Å; F444-C451 PolarHBondContact O-N 3.1Å; F444-M454 HydrophobicContact CB-CB 4.41Å; F444-M454 HydrophobicContact CB-CG 4.17Å; F444-M454 HydrophobicContact CB-SD 3.92Å; F444-M454 HydrophobicContact CD1-CB 3.94Å; F444-M454 HydrophobicContact CD1-CG 3.86Å; F444-M454 HydrophobicContact CD2-CG 3.73Å; F444-M454 HydrophobicContact CD2-SD 3.86Å; F444-M454 HydrophobicContact CE1-CB 4.39Å; F444-M454 HydrophobicContact CE1-CG 4.16Å; F444-M454 HydrophobicContact CE2-CG 4.05Å; F444-M454 HydrophobicContact CG-CB 4.08Å; F444-M454 HydrophobicContact CG-CG 3.63Å; F444-M454 HydrophobicContact CG-SD 3.9Å; F444-M454 HydrophobicContact CZ-CG 4.25Å; F444-Q458 HydrophobicContact CE2-CG 4.44Å; F444-Q458 HydrophobicContact CZ-CG 4.23Å
445G97.6Very high96.8Very high13 Ų1341.1 Ų41.113%0.13423%0.233CC..  trans59.5-172.5-163.700000113.2L442L442-G445 PolarHBondContact O-N 3.3Å
446D97.6Very high96.8Very high32 Ų3237.5 Ų37.517%0.17120%0.2CC..  trans-141.1168.9-178.7-151.9-13.5000111.9L93 I94 S438 V439 L442L93-D446 HydrophobicContact CD1-CB 4.24Å; I94-D446 WeakPolarHBondContact CD1-OD2 3.2Å; S438-D446 WeakPolarHBondContact CB-OD2 3.17Å; S438-D446 PolarHBondContact OG-OD2 3.32Å; V439-D446 HydrophobicContact CG1-CB 4.49Å; L442-D446 HydrophobicContact CD2-CB 3.74Å
447G97.4Very high96.8Very high14 Ų1436.1 Ų36.114%0.14420%0.199CC..SBendtrans72.1-167.9-179.200000114.4L93 R449 N450L93-G447 WeakPolarHBondContact O-CA 3.09Å; G447-R449 PolarHBondContact O-N 3.33Å; G447-N450 WeakPolarHBondContact O-CB 3.48Å; G447-N450 PolarHBondContact O-N 3.43Å; G447-N450 VanDerWaalsContact O-N 3.07Å
448P97.5Very high96.8Very high65 Ų6534 Ų3442%0.42219%0.19SC..THydrogen-bonded Turntrans-60-18.4-173.4-26.936.3000115.4F97 W126F97-P448 HydrophobicContact CB-CG 4.42Å; F97-P448 HydrophobicContact CD1-CB 3.91Å; F97-P448 HydrophobicContact CD1-CG 3.63Å; F97-P448 HydrophobicContact CD2-CG 4.3Å; F97-P448 HydrophobicContact CE1-CB 3.69Å; F97-P448 HydrophobicContact CE1-CG 3.97Å; F97-P448 HydrophobicContact CE2-CB 4.32Å; F97-P448 HydrophobicContact CG-CB 4.33Å; F97-P448 HydrophobicContact CG-CG 3.83Å; F97-P448 HydrophobicContact CZ-CB 3.91Å; F97-P448 HydrophobicContact CZ-CG 4.45Å; W126-P448 HydrophobicContact CH2-CB 4.45Å
449R96.9Very high96.8Very high3 Ų331.5 Ų31.51%0.01117%0.171CC..THydrogen-bonded Turntrans-11124.4-179.2-160.2158.4179.8166.2-4.5113.3F97 A101 D102 R103 L121 D122 W126 G447F97-R449 HydrophobicContact CE2-CB 3.64Å; F97-R449 HydrophobicContact CZ-CB 3.9Å; A101-R449 WeakPolarHBondContact O-CD 3.45Å; A101-R449 PolarHBondContact O-NH1 3.48Å; D102-R449 IonicContact OD1-NH1 3.76Å; R103-R449 PolarHBondContact NH2-O 3.43Å; L121-R449 PolarHBondContact O-NH1 3.5Å; L121-R449 PolarHBondContact O-NH2 3.04Å; D122-R449 IonicContact OD1-CZ 3.98Å; D122-R449 IonicContact OD1-NH1 3.12Å; D122-R449 PolarHBondContact OD1-NH1 3.17Å; D122-R449 IonicContact OD1-NH2 2.64Å; D122-R449 PolarHBondContact OD1-NH2 2.91Å; D122-R449 VanDerWaalsContact OD1-NH2 3.17Å; W126-R449 VanDerWaalsContact CD1-CZ 3.48Å; W126-R449 VanDerWaalsContact CE2-CD 3.45Å; W126-R449 HydrophobicContact CH2-CB 4.08Å; W126-R449 HydrophobicContact CH2-CG 4.32Å; W126-R449 HydrophobicContact CZ2-CB 3.57Å; W126-R449 HydrophobicContact CZ2-CG 3.45Å; W126-R449 VanDerWaalsContact CZ2-CG 3.45Å; G447-R449 PolarHBondContact O-N 3.33Å
450N97.4Very high96.7Very high42 Ų4231.5 Ų31.523%0.22517%0.171CC..SBendtrans-65.5174.816975.9-13000112.6R130 G447 I452R130-N450 PolarHBondContact NH1-O 3.32Å; R130-N450 PolarHBondContact NH2-O 2.97Å; R130-N450 PolarHBondContact NH2-OD1 3.29Å; G447-N450 WeakPolarHBondContact O-CB 3.48Å; G447-N450 PolarHBondContact O-N 3.43Å; G447-N450 VanDerWaalsContact O-N 3.07Å; N450-I452 PolarHBondContact O-N 3.11Å
451C97.8Very high96.7Very high54 Ų5429.9 Ų29.937%0.36516%0.164SC..  trans-60.6117.7177-174.90000111.4F444 G453 M454F444-C451 HydrophobicContact CB-CB 3.85Å; F444-C451 HydrophobicContact CD1-CB 3.87Å; F444-C451 HydrophobicContact CG-CB 4.34Å; F444-C451 WeakPolarHBondContact O-CB 3.48Å; F444-C451 PolarHBondContact O-N 3.1Å; C451-G453 VanDerWaalsContact C-N 3.26Å; C451-G453 PolarHBondContact O-N 3.15Å; C451-G453 PolarHBondContact SG-N 3.48Å; C451-M454 HydrophobicContact CB-CB 4.36Å
452I96.5Very high96.7Very high26 Ų2629.9 Ų29.913%0.13316%0.164CC..THydrogen-bonded Turntrans-67.3-31.3176.8-157.2176.4000111.8L118 L133 F137 F307 N450L118-I452 HydrophobicContact CD2-CB 4.31Å; L118-I452 HydrophobicContact CD2-CD1 3.89Å; L118-I452 HydrophobicContact CD2-CG2 4.01Å; L133-I452 HydrophobicContact CB-CD1 3.72Å; F137-I452 WeakPolarHBondContact CB-O 3.15Å; F137-I452 HydrophobicContact CD2-CB 4.49Å; F137-I452 HydrophobicContact CD2-CD1 3.82Å; F137-I452 HydrophobicContact CD2-CG1 3.66Å; F137-I452 HydrophobicContact CD2-CG2 4.31Å; F137-I452 HydrophobicContact CE2-CD1 4.13Å; F137-I452 HydrophobicContact CE2-CG1 4.23Å; F137-I452 HydrophobicContact CE2-CG2 4.12Å; F137-I452 HydrophobicContact CG-CG1 4.26Å; F137-I452 WeakPolarHBondContact CG-O 3.29Å; F307-I452 HydrophobicContact CE1-CG2 3.63Å; F307-I452 HydrophobicContact CZ-CG2 3.89Å; N450-I452 PolarHBondContact O-N 3.11Å
453G95.3Very high96.7Very high17 Ų1729.8 Ų29.818%0.17516%0.164CC..THydrogen-bonded Turntrans-896.5-175.700000114.5C451 R455 F456 G457C451-G453 VanDerWaalsContact C-N 3.26Å; C451-G453 PolarHBondContact O-N 3.15Å; C451-G453 PolarHBondContact SG-N 3.48Å; G453-R455 VanDerWaalsContact C-N 3.32Å; G453-R455 PolarHBondContact O-N 3.44Å; G453-F456 PolarHBondContact O-N 2.9Å; G453-G457 PolarHBondContact O-N 3.15Å
454M96.2Very high96.7Very high54 Ų5428.7 Ų28.727%0.26616%0.156SC..Hα-helixtrans-49.5-49.9-173.7176.8177.470.300112.7F444 C451 F456 G457 Q458F444-M454 HydrophobicContact CB-CB 4.41Å; F444-M454 HydrophobicContact CB-CG 4.17Å; F444-M454 HydrophobicContact CB-SD 3.92Å; F444-M454 HydrophobicContact CD1-CB 3.94Å; F444-M454 HydrophobicContact CD1-CG 3.86Å; F444-M454 HydrophobicContact CD2-CG 3.73Å; F444-M454 HydrophobicContact CD2-SD 3.86Å; F444-M454 HydrophobicContact CE1-CB 4.39Å; F444-M454 HydrophobicContact CE1-CG 4.16Å; F444-M454 HydrophobicContact CE2-CG 4.05Å; F444-M454 HydrophobicContact CG-CB 4.08Å; F444-M454 HydrophobicContact CG-CG 3.63Å; F444-M454 HydrophobicContact CG-SD 3.9Å; F444-M454 HydrophobicContact CZ-CG 4.25Å; C451-M454 HydrophobicContact CB-CB 4.36Å; M454-F456 PolarHBondContact O-N 2.95Å; M454-G457 PolarHBondContact O-N 3.11Å; M454-Q458 WeakPolarHBondContact O-CB 3.18Å; M454-Q458 VanDerWaalsContact O-CG 3.32Å; M454-Q458 WeakPolarHBondContact O-CG 3.45Å; M454-Q458 PolarHBondContact O-N 3.32Å
455R94.6Very high96.7Very high121 Ų12126.9 Ų26.946%0.45715%0.148SC..Hα-helixtrans-64.7-38.5-179.3-66.7178.2177.7159.2-4112.7F137 M142 G453 M459F137-R455 PolarHBondContact O-NH1 3.31Å; M142-R455 HydrophobicContact CG-CB 4Å; M142-R455 HydrophobicContact SD-CB 4.1Å; G453-R455 VanDerWaalsContact C-N 3.32Å; G453-R455 PolarHBondContact O-N 3.44Å; R455-M459 VanDerWaalsContact O-CB 3.32Å; R455-M459 WeakPolarHBondContact O-CB 3.29Å; R455-M459 PolarHBondContact O-N 3.04Å
456F94.8Very high96.7Very high13 Ų1326.2 Ų26.26%0.05714%0.142CC..Hα-helixtrans-68.6-46178.2-178.6-95.9000111.2F137 M142 M145 V186 I187 C190 G453 M454 M459 Q460F137-F456 HydrophobicContact CD1-CB 4.28Å; F137-F456 HydrophobicContact CE1-CB 4.3Å; M142-F456 HydrophobicContact SD-CB 3.84Å; M142-F456 HydrophobicContact SD-CD2 4.28Å; M145-F456 HydrophobicContact CE-CD2 3.89Å; M145-F456 HydrophobicContact CE-CE2 4.23Å; M145-F456 HydrophobicContact SD-CD2 4.44Å; M145-F456 HydrophobicContact SD-CE2 4.18Å; V186-F456 HydrophobicContact CG1-CE1 4.32Å; V186-F456 HydrophobicContact CG1-CZ 3.72Å; I187-F456 HydrophobicContact CD1-CE1 3.75Å; I187-F456 HydrophobicContact CD1-CZ 4.06Å; C190-F456 HydrophobicContact CB-CE2 4.03Å; C190-F456 HydrophobicContact CB-CZ 4.13Å; G453-F456 PolarHBondContact O-N 2.9Å; M454-F456 PolarHBondContact O-N 2.95Å; F456-M459 HydrophobicContact CD2-CE 3.73Å; F456-M459 HydrophobicContact CE2-CE 4.07Å; F456-M459 PolarHBondContact O-N 3.32Å; F456-Q460 PolarHBondContact O-N 3.12Å
457G95.7Very high96.6Very high13 Ų1325 Ų2513%0.13414%0.135CC..Hα-helixtrans-57.9-47.9174.900000112.2G453 M454 M459 Q460 A461G453-G457 PolarHBondContact O-N 3.15Å; M454-G457 PolarHBondContact O-N 3.11Å; G457-M459 PolarHBondContact O-N 2.64Å; G457-Q460 WeakPolarHBondContact O-CG 3.11Å; G457-A461 VanDerWaalsContact O-CB 3.28Å; G457-A461 WeakPolarHBondContact O-CB 3.3Å; G457-A461 PolarHBondContact O-N 3.35Å
458Q96.1Very high96.6Very high35 Ų3524.6 Ų24.616%0.16413%0.129CC..Hα-helixtrans-60.8-42.7175.3-74.5176.5-27.600112.3F444 M454 A461 R462F444-Q458 HydrophobicContact CE2-CG 4.44Å; F444-Q458 HydrophobicContact CZ-CG 4.23Å; M454-Q458 WeakPolarHBondContact O-CB 3.18Å; M454-Q458 VanDerWaalsContact O-CG 3.32Å; M454-Q458 WeakPolarHBondContact O-CG 3.45Å; M454-Q458 PolarHBondContact O-N 3.32Å; Q458-A461 PolarHBondContact O-N 2.86Å; Q458-R462 WeakPolarHBondContact O-CB 3.38Å; Q458-R462 WeakPolarHBondContact O-CD 3.22Å; Q458-R462 WeakPolarHBondContact O-CG 3.39Å; Q458-R462 PolarHBondContact O-N 2.76Å
459M95.5Very high96.6Very high7 Ų721.5 Ų21.53%0.03411%0.109CC..Hα-helixtrans-60.2-52.8179179.2176.963.600111.7M142 M145 F146 V149 R455 F456 G457 A461 R462 I463M142-M459 HydrophobicContact CB-SD 4.23Å; M142-M459 HydrophobicContact SD-CE 4.2Å; M145-M459 HydrophobicContact CB-CE 4.44Å; F146-M459 HydrophobicContact CB-SD 4.19Å; F146-M459 HydrophobicContact CD2-CG 4.09Å; F146-M459 HydrophobicContact CD2-SD 3.84Å; V149-M459 HydrophobicContact CG2-CE 3.98Å; R455-M459 VanDerWaalsContact O-CB 3.32Å; R455-M459 WeakPolarHBondContact O-CB 3.29Å; R455-M459 PolarHBondContact O-N 3.04Å; F456-M459 HydrophobicContact CD2-CE 3.73Å; F456-M459 HydrophobicContact CE2-CE 4.07Å; F456-M459 PolarHBondContact O-N 3.32Å; G457-M459 PolarHBondContact O-N 2.64Å; M459-A461 VanDerWaalsContact C-N 3.35Å; M459-A461 PolarHBondContact O-N 3.46Å; M459-R462 PolarHBondContact O-N 3.16Å; M459-I463 HydrophobicContact CG-CD1 3.81Å; M459-I463 WeakPolarHBondContact O-CD1 3.34Å; M459-I463 VanDerWaalsContact O-CG1 3.28Å; M459-I463 WeakPolarHBondContact O-CG1 3.27Å; M459-I463 PolarHBondContact O-N 3.49Å
460Q95.1Very high96.6Very high0 Ų022 Ų220%011%0.113CC..Hα-helixtrans-67-35.9-179.667.5176.3-46.900112.4V149 V186 G311 S315 F456 G457 I463 G464V149-Q460 HydrophobicContact CG1-CB 4.31Å; V186-Q460 HydrophobicContact CG1-CB 4.09Å; G311-Q460 PolarHBondContact O-NE2 2.9Å; S315-Q460 PolarHBondContact OG-NE2 3.03Å; F456-Q460 PolarHBondContact O-N 3.12Å; G457-Q460 WeakPolarHBondContact O-CG 3.11Å; Q460-I463 PolarHBondContact O-N 3.29Å; Q460-G464 PolarHBondContact O-N 2.88Å
461A97.6Very high96.4Very high3 Ų324.5 Ų24.53%0.02512%0.12CC..Hα-helixtrans-64.9-46177.200000111.9M319 G457 Q458 M459 G464 L465M319-A461 HydrophobicContact CG-CB 3.99Å; M319-A461 HydrophobicContact SD-CB 4.48Å; G457-A461 VanDerWaalsContact O-CB 3.28Å; G457-A461 WeakPolarHBondContact O-CB 3.3Å; G457-A461 PolarHBondContact O-N 3.35Å; Q458-A461 PolarHBondContact O-N 2.86Å; M459-A461 VanDerWaalsContact C-N 3.35Å; M459-A461 PolarHBondContact O-N 3.46Å; A461-G464 PolarHBondContact O-N 2.95Å; A461-L465 VanDerWaalsContact O-CB 3.32Å; A461-L465 WeakPolarHBondContact O-CB 3.44Å; A461-L465 WeakPolarHBondContact O-CD1 3.27Å; A461-L465 VanDerWaalsContact O-CG 3.26Å; A461-L465 WeakPolarHBondContact O-CG 3.32Å; A461-L465 PolarHBondContact O-N 3.18Å
462R97.9Very high96.4Very high52 Ų5222 Ų2220%0.19610%0.103CC..Hα-helixtrans-61-46.9176.6-70.3163.9-174.5169.5-6.8111.6I356 L362 N363 I366 Q458 M459 A466I356-R462 HydrophobicContact CD1-CB 4.05Å; I356-R462 HydrophobicContact CG2-CB 3.73Å; I356-R462 HydrophobicContact CG2-CG 4.26Å; L362-R462 HydrophobicContact CD2-CB 3.93Å; L362-R462 HydrophobicContact CD2-CG 4.15Å; L362-R462 HydrophobicContact CG-CG 4.44Å; N363-R462 PolarHBondContact OD1-NE 3.39Å; N363-R462 PolarHBondContact OD1-NH2 2.86Å; I366-R462 HydrophobicContact CD1-CB 4.38Å; I366-R462 HydrophobicContact CD1-CG 3.57Å; Q458-R462 WeakPolarHBondContact O-CB 3.38Å; Q458-R462 WeakPolarHBondContact O-CD 3.22Å; Q458-R462 WeakPolarHBondContact O-CG 3.39Å; Q458-R462 PolarHBondContact O-N 2.76Å; M459-R462 PolarHBondContact O-N 3.16Å; R462-A466 WeakPolarHBondContact O-CB 3.4Å; R462-A466 PolarHBondContact O-N 2.7Å
463I97.5Very high96.4Very high0 Ų024.3 Ų24.30%011%0.11CC..Hα-helixtrans-62.3-50.6179.1-67.9164.2000110.3F146 V149 I150 I356 M459 Q460 L465 A466 Q467F146-I463 HydrophobicContact CD2-CD1 3.87Å; F146-I463 HydrophobicContact CE2-CD1 3.59Å; F146-I463 HydrophobicContact CE2-CG1 4.06Å; F146-I463 HydrophobicContact CZ-CD1 4.24Å; V149-I463 HydrophobicContact CB-CD1 3.92Å; V149-I463 HydrophobicContact CG1-CB 4.42Å; V149-I463 HydrophobicContact CG1-CD1 3.54Å; V149-I463 HydrophobicContact CG1-CG2 4.31Å; I150-I463 HydrophobicContact CD1-CD1 4.18Å; I150-I463 HydrophobicContact CD1-CG1 4.27Å; I150-I463 HydrophobicContact CD1-CG2 3.98Å; I356-I463 HydrophobicContact CD1-CG1 4.01Å; I356-I463 HydrophobicContact CG1-CG1 4.17Å; M459-I463 HydrophobicContact CG-CD1 3.81Å; M459-I463 WeakPolarHBondContact O-CD1 3.34Å; M459-I463 VanDerWaalsContact O-CG1 3.28Å; M459-I463 WeakPolarHBondContact O-CG1 3.27Å; M459-I463 PolarHBondContact O-N 3.49Å; Q460-I463 PolarHBondContact O-N 3.29Å; I463-L465 PolarHBondContact O-N 3.35Å; I463-A466 PolarHBondContact O-N 2.66Å; I463-Q467 HydrophobicContact CG2-CG 4.27Å; I463-Q467 WeakPolarHBondContact O-CB 3.38Å; I463-Q467 WeakPolarHBondContact O-CG 3.49Å; I463-Q467 PolarHBondContact O-N 2.62Å
464G97.5Very high96.5Very high0 Ų023.5 Ų23.50%010%0.102CC..Hα-helixtrans-59.1-46.4-179.300000112.6Q460 A461 Q467 I468Q460-G464 PolarHBondContact O-N 2.88Å; A461-G464 PolarHBondContact O-N 2.95Å; G464-Q467 PolarHBondContact O-N 3.44Å; G464-I468 WeakPolarHBondContact O-CG1 3.46Å; G464-I468 PolarHBondContact O-N 3Å
465L98.5Very high96.6Very high0 Ų022.1 Ų22.10%010%0.097CC..Hα-helixtrans-67.9-44.7178.3-70.3167.4000112.3M319 C322 L323 L362 I366 A461 I463 Q467 I468 I469M319-L465 HydrophobicContact CB-CD2 4.2Å; M319-L465 HydrophobicContact CB-CG 4.36Å; M319-L465 HydrophobicContact CG-CD1 4.26Å; M319-L465 HydrophobicContact CG-CD2 4.37Å; M319-L465 HydrophobicContact CG-CG 3.98Å; C322-L465 HydrophobicContact CB-CD1 4.09Å; C322-L465 HydrophobicContact CB-CD2 4.03Å; L323-L465 HydrophobicContact CD1-CD2 4.42Å; L323-L465 HydrophobicContact CD2-CD2 3.85Å; L323-L465 HydrophobicContact CG-CD2 3.79Å; L362-L465 HydrophobicContact CD1-CB 4.04Å; L362-L465 HydrophobicContact CD1-CD1 4.43Å; I366-L465 HydrophobicContact CD1-CD1 3.81Å; I366-L465 HydrophobicContact CG1-CD1 3.58Å; A461-L465 VanDerWaalsContact O-CB 3.32Å; A461-L465 WeakPolarHBondContact O-CB 3.44Å; A461-L465 WeakPolarHBondContact O-CD1 3.27Å; A461-L465 VanDerWaalsContact O-CG 3.26Å; A461-L465 WeakPolarHBondContact O-CG 3.32Å; A461-L465 PolarHBondContact O-N 3.18Å; I463-L465 PolarHBondContact O-N 3.35Å; L465-Q467 VanDerWaalsContact C-N 3.28Å; L465-Q467 PolarHBondContact O-N 3.01Å; L465-I468 PolarHBondContact O-N 3.33Å; L465-I469 WeakPolarHBondContact O-CB 3.36Å; L465-I469 WeakPolarHBondContact O-CG1 3.5Å; L465-I469 PolarHBondContact O-N 2.79Å
466A97.8Very high96.7Very high0 Ų019.3 Ų19.30%09%0.093CC..Hα-helixtrans-59.8-41.2177.700000111.2I340 L351 I356 M359 L362 R462 I463 I468 S470I340-A466 HydrophobicContact CD1-CB 4.45Å; I340-A466 HydrophobicContact CG2-CB 4.39Å; L351-A466 HydrophobicContact CD2-CB 4.23Å; I356-A466 HydrophobicContact CD1-CB 4.21Å; M359-A466 HydrophobicContact SD-CB 4.12Å; L362-A466 HydrophobicContact CD2-CB 4.2Å; R462-A466 WeakPolarHBondContact O-CB 3.4Å; R462-A466 PolarHBondContact O-N 2.7Å; I463-A466 PolarHBondContact O-N 2.66Å; A466-I468 PolarHBondContact O-N 2.88Å; A466-S470 VanDerWaalsContact O-CB 3.23Å; A466-S470 WeakPolarHBondContact O-CB 3.5Å; A466-S470 PolarHBondContact O-N 3.08Å; A466-S470 VanDerWaalsContact O-N 3.12Å; A466-S470 PolarHBondContact O-OG 2.91Å
467Q95.8Very high96.8Very high6 Ų619.4 Ų19.43%0.02810%0.095CC..Hα-helixtrans-62.8-40177.5-71.8-76.930.300113S153 V157 L351 I463 G464 L465 S470 R471S153-Q467 PolarHBondContact OG-NE2 2.73Å; V157-Q467 HydrophobicContact CG2-CB 3.75Å; V157-Q467 HydrophobicContact CG2-CG 4.27Å; L351-Q467 HydrophobicContact CD1-CG 3.68Å; I463-Q467 HydrophobicContact CG2-CG 4.27Å; I463-Q467 WeakPolarHBondContact O-CB 3.38Å; I463-Q467 WeakPolarHBondContact O-CG 3.49Å; I463-Q467 PolarHBondContact O-N 2.62Å; G464-Q467 PolarHBondContact O-N 3.44Å; L465-Q467 VanDerWaalsContact C-N 3.28Å; L465-Q467 PolarHBondContact O-N 3.01Å; Q467-S470 PolarHBondContact O-OG 3.18Å; Q467-R471 PolarHBondContact O-NH1 2.77Å
468I97.3Very high96.8Very high5 Ų526.7 Ų26.73%0.02613%0.131CC..Hα-helixtrans-71.5-56.8177.2-65.3168.5000110.5F156 I160 M179 L323 G464 L465 A466 S470 R471 F472 V474F156-I468 HydrophobicContact CE1-CD1 3.78Å; F156-I468 HydrophobicContact CE1-CG1 3.75Å; F156-I468 HydrophobicContact CZ-CD1 3.86Å; F156-I468 HydrophobicContact CZ-CG1 4.15Å; I160-I468 HydrophobicContact CD1-CD1 4.5Å; I160-I468 HydrophobicContact CD1-CG1 4.05Å; M179-I468 HydrophobicContact CE-CD1 3.55Å; M179-I468 HydrophobicContact SD-CD1 4.31Å; L323-I468 HydrophobicContact CD1-CD1 3.69Å; L323-I468 HydrophobicContact CD2-CD1 4.38Å; L323-I468 HydrophobicContact CD2-CG2 3.99Å; G464-I468 WeakPolarHBondContact O-CG1 3.46Å; G464-I468 PolarHBondContact O-N 3Å; L465-I468 PolarHBondContact O-N 3.33Å; A466-I468 PolarHBondContact O-N 2.88Å; I468-S470 VanDerWaalsContact C-N 3.27Å; I468-S470 PolarHBondContact O-N 3.5Å; I468-R471 PolarHBondContact O-N 2.77Å; I468-R471 VanDerWaalsContact O-N 3.07Å; I468-F472 HydrophobicContact CG2-CB 4.36Å; I468-F472 WeakPolarHBondContact O-CB 3.38Å; I468-F472 WeakPolarHBondContact O-CD2 3.13Å; I468-F472 PolarHBondContact O-N 3.33Å; I468-V474 HydrophobicContact CG2-CG2 3.92Å
469I97.9Very high96.7Very high0 Ų029.2 Ų29.20%015%0.149CC..Hα-helixtrans-67-28.5-168.8-62.2-55.7000112.6L323 L326 Q333 L336 R337 I340 L465 R471L323-I469 HydrophobicContact CD2-CD1 3.92Å; L326-I469 HydrophobicContact CD1-CD1 3.83Å; L326-I469 HydrophobicContact CD1-CG1 4.09Å; Q333-I469 HydrophobicContact CG-CD1 4.06Å; Q333-I469 HydrophobicContact CG-CG2 4.49Å; L336-I469 HydrophobicContact CD2-CG1 4.27Å; L336-I469 HydrophobicContact CD2-CG2 4.27Å; L336-I469 HydrophobicContact CG-CG2 4.17Å; R337-I469 HydrophobicContact CB-CG2 3.86Å; R337-I469 WeakPolarHBondContact CG-O 3.42Å; R337-I469 PolarHBondContact NE-O 3.09Å; I340-I469 HydrophobicContact CD1-CB 3.94Å; I340-I469 HydrophobicContact CD1-CG2 3.88Å; L465-I469 WeakPolarHBondContact O-CB 3.36Å; L465-I469 WeakPolarHBondContact O-CG1 3.5Å; L465-I469 PolarHBondContact O-N 2.79Å; I469-R471 VanDerWaalsContact C-N 3.31Å; I469-R471 PolarHBondContact O-N 2.9Å
470S95.4Very high96.8Very high14 Ų1429.7 Ų29.710%0.09815%0.152CC..THydrogen-bonded Turntrans-70.2-21.9175.153.60000114.8A466 Q467 I468A466-S470 VanDerWaalsContact O-CB 3.23Å; A466-S470 WeakPolarHBondContact O-CB 3.5Å; A466-S470 PolarHBondContact O-N 3.08Å; A466-S470 VanDerWaalsContact O-N 3.12Å; A466-S470 PolarHBondContact O-OG 2.91Å; Q467-S470 PolarHBondContact O-OG 3.18Å; I468-S470 VanDerWaalsContact C-N 3.27Å; I468-S470 PolarHBondContact O-N 3.5Å
471R94.1Very high96.9Very high94 Ų9432.4 Ų32.436%0.35517%0.165SC..THydrogen-bonded Turntrans-125-15.7-170.8-70.2175.5-175.977.4-6.5114.4Q467 I468 I469 I506Q467-R471 PolarHBondContact O-NH1 2.77Å; I468-R471 PolarHBondContact O-N 2.77Å; I468-R471 VanDerWaalsContact O-N 3.07Å; I469-R471 VanDerWaalsContact C-N 3.31Å; I469-R471 PolarHBondContact O-N 2.9Å; R471-I506 VanDerWaalsContact O-CG1 3.28Å; R471-I506 WeakPolarHBondContact O-CG1 3.42Å; R471-I506 PolarHBondContact O-N 3.46Å
472F96.6Very high96.8Very high3 Ų336.6 Ų36.61%0.01319%0.186CC..EExtended strand (participates in β ladder)trans-134.3147.3-176.6-54.3-87.8000110.5V157 I160 V164 R337 I468 V503 E504 R505V157-F472 HydrophobicContact CG1-CE2 4.47Å; I160-F472 HydrophobicContact CB-CE1 4.44Å; I160-F472 HydrophobicContact CB-CE2 4.22Å; I160-F472 HydrophobicContact CB-CZ 3.89Å; I160-F472 HydrophobicContact CG2-CD1 4.04Å; I160-F472 HydrophobicContact CG2-CD2 4.29Å; I160-F472 HydrophobicContact CG2-CE1 3.51Å; I160-F472 HydrophobicContact CG2-CE2 3.82Å; I160-F472 HydrophobicContact CG2-CG 4.4Å; I160-F472 HydrophobicContact CG2-CZ 3.4Å; V164-F472 HydrophobicContact CB-CE1 4.41Å; R337-F472 PolarHBondContact NH2-O 3.17Å; R337-F472 VanDerWaalsContact NH2-O 3.15Å; I468-F472 HydrophobicContact CG2-CB 4.36Å; I468-F472 WeakPolarHBondContact O-CB 3.38Å; I468-F472 WeakPolarHBondContact O-CD2 3.13Å; I468-F472 PolarHBondContact O-N 3.33Å; F472-V503 HydrophobicContact CB-CG1 3.72Å; F472-V503 HydrophobicContact CD1-CG1 3.74Å; F472-V503 HydrophobicContact CG-CG1 3.89Å; F472-E504 CarbonylContact C-O 3.56Å; F472-E504 WeakPolarHBondContact CA-O 3.09Å; F472-E504 WeakPolarHBondContact CB-O 3.37Å; F472-R505 HydrophobicContact CD1-CG 3.96Å; F472-R505 HydrophobicContact CE1-CG 3.68Å
473R96.9Very high96.6Very high73 Ų7339.2 Ų39.228%0.27521%0.21SC..EExtended strand (participates in β ladder)trans-95.1134.7161.5-177.5177.5-69.9-91.6-1108.1D334 V503 E504 I506D334-R473 IonicContact OD1-CZ 3.43Å; D334-R473 IonicContact OD1-NH1 2.73Å; D334-R473 PolarHBondContact OD1-NH1 3.14Å; D334-R473 VanDerWaalsContact OD1-NH1 3.11Å; D334-R473 IonicContact OD1-NH2 2.74Å; D334-R473 PolarHBondContact OD1-NH2 3.07Å; D334-R473 VanDerWaalsContact OD1-NH2 3.07Å; D334-R473 IonicContact OD2-NH1 3.29Å; D334-R473 IonicContact OD2-NH2 3.12Å; R473-V503 WeakPolarHBondContact O-CA 3.41Å; R473-E504 HydrophobicContact CB-CB 4.43Å; R473-E504 PolarHBondContact N-O 2.84Å; R473-E504 PolarHBondContact O-N 3.05Å; R473-I506 HydrophobicContact CB-CG2 3.99Å
474V97.8Very high96.4Very high1 Ų139.9 Ų39.91%0.00621%0.213CC..EExtended strand (participates in β ladder)trans-114.3131.7175.5-172.70000108.7L323 A327 Q330 Q333 I468 L501 R502 V503L323-V474 HydrophobicContact CD2-CG2 4.29Å; A327-V474 WeakPolarHBondContact CA-O 3.45Å; A327-V474 HydrophobicContact CB-CG1 4.13Å; Q330-V474 PolarHBondContact NE2-O 2.85Å; Q333-V474 PolarHBondContact NE2-O 3.38Å; I468-V474 HydrophobicContact CG2-CG2 3.92Å; V474-L501 HydrophobicContact CG1-CB 3.6Å; V474-L501 HydrophobicContact CG1-CD1 3.44Å; V474-L501 VanDerWaalsContact CG1-CD1 3.44Å; V474-L501 HydrophobicContact CG1-CG 4.08Å; V474-R502 CarbonylContact C-O 3.51Å; V474-R502 VanDerWaalsContact CA-O 3.31Å; V474-R502 WeakPolarHBondContact CA-O 3.42Å; V474-V503 HydrophobicContact CG2-CG2 4.4Å
475S97.8Very high96.1Very high24 Ų2446 Ų4617%0.16824%0.24CC..EExtended strand (participates in β ladder)trans-140.9162.4-178.657.60000111R502S475-R502 PolarHBondContact N-O 2.84Å; S475-R502 PolarHBondContact O-N 2.8Å
476V97.8Very high95.8Very high62 Ų6248.4 Ų48.438%0.37625%0.249SC..  trans-67.3154174.1-59.20000110.5A327 Q328 T480 I482A327-V476 HydrophobicContact CB-CG1 4.2Å; Q328-V476 HydrophobicContact CG-CG1 3.61Å; V476-T480 HydrophobicContact CB-CG2 4.38Å; V476-T480 HydrophobicContact CG1-CG2 4.25Å; V476-I482 HydrophobicContact CB-CD1 4.29Å; V476-I482 HydrophobicContact CG1-CD1 3.81Å
477C95.7Very high95.3Very high15 Ų1549.8 Ų49.810%0.10126%0.259CS..  trans-137174.517670.40000110.4V172 T479 T480 R502V172-C477 HydrophobicContact CG2-CB 4.15Å; C477-T479 PolarHBondContact O-N 2.98Å; C477-T479 VanDerWaalsContact O-N 3.07Å; C477-T480 PolarHBondContact N-OG1 2.66Å; C477-T480 VanDerWaalsContact O-CB 3.3Å; C477-T480 WeakPolarHBondContact O-CB 3.42Å; C477-T480 PolarHBondContact O-N 3.33Å; C477-T480 PolarHBondContact O-OG1 2.87Å; C477-T480 PolarHBondContact SG-OG1 3.31Å; C477-R502 HydrophobicContact CB-CB 4.15Å
478D95.4Very high94.6Very high167 Ų16750.9 Ų50.989%0.89327%0.267SS*.THydrogen-bonded Turntrans-59.7-23.9-177.5-55.5-26.5000113.5
479T95.5Very high93.3Very high87 Ų8755.6 Ų55.653%0.53429%0.29SS..THydrogen-bonded Turntrans-90.9-7.3177.8-440000112.8C477 E481 Y500C477-T479 PolarHBondContact O-N 2.98Å; C477-T479 VanDerWaalsContact O-N 3.07Å; T479-E481 PolarHBondContact O-N 2.96Å; T479-Y500 HydrophobicContact CG2-CD1 4.44Å; T479-Y500 HydrophobicContact CG2-CD2 3.94Å; T479-Y500 HydrophobicContact CG2-CG 3.89Å
480T97.2Very high92.2Very high17 Ų1756.7 Ų56.710%0.10430%0.298CS..  trans-70.1118.7-179.8-540000109.9Y324 V476 C477 I482 Y500 L501Y324-T480 HydrophobicContact CD2-CG2 4.27Å; Y324-T480 HydrophobicContact CE2-CG2 4.05Å; V476-T480 HydrophobicContact CB-CG2 4.38Å; V476-T480 HydrophobicContact CG1-CG2 4.25Å; C477-T480 PolarHBondContact N-OG1 2.66Å; C477-T480 VanDerWaalsContact O-CB 3.3Å; C477-T480 WeakPolarHBondContact O-CB 3.42Å; C477-T480 PolarHBondContact O-N 3.33Å; C477-T480 PolarHBondContact O-OG1 2.87Å; C477-T480 PolarHBondContact SG-OG1 3.31Å; T480-I482 HydrophobicContact CG2-CD1 4.1Å; T480-I482 HydrophobicContact CG2-CG1 3.9Å; T480-I482 PolarHBondContact O-N 2.77Å; T480-Y500 WeakPolarHBondContact CB-O 3.47Å; T480-Y500 PolarHBondContact OG1-O 2.92Å; T480-L501 HydrophobicContact CG2-CD2 3.77Å
481E96.4Very high91.2Very high58 Ų5861.8 Ų61.827%0.27132%0.322SS..  trans-79114.6177.4-176.1166.6-138.200110.7Y324 T479 L484 K485Y324-E481 WeakPolarHBondContact CE2-O 3.48Å; Y324-E481 PolarHBondContact OH-O 3.3Å; T479-E481 PolarHBondContact O-N 2.96Å; E481-L484 HydrophobicContact CB-CD2 4.47Å; E481-L484 WeakPolarHBondContact O-CD2 3.42Å; E481-L484 PolarHBondContact O-N 2.81Å; E481-K485 WeakPolarHBondContact OE1-CD 3.44Å; E481-K485 VanDerWaalsContact OE1-CE 3.24Å; E481-K485 WeakPolarHBondContact OE1-CE 3.46Å; E481-K485 VanDerWaalsContact OE1-CG 3.29Å; E481-K485 WeakPolarHBondContact OE1-CG 3.4Å; E481-K485 IonicContact OE1-NZ 2.69Å; E481-K485 PolarHBondContact OE1-NZ 2.75Å
482I95.3Very high90.8Very high91 Ų9158.2 Ų58.247%0.46731%0.311SS..SBendtrans-129.6117.9179.8-55.9173.9000108.8Y324 Q328 V476 T480Y324-I482 HydrophobicContact CE2-CG1 4.14Å; Q328-I482 HydrophobicContact CG-CD1 4.22Å; V476-I482 HydrophobicContact CB-CD1 4.29Å; V476-I482 HydrophobicContact CG1-CD1 3.81Å; T480-I482 HydrophobicContact CG2-CD1 4.1Å; T480-I482 HydrophobicContact CG2-CG1 3.9Å; T480-I482 PolarHBondContact O-N 2.77Å
483P93.7Very high90.5Very high107 Ų10758.4 Ų58.470%0.69531%0.312SS*.SBendcis-72.5154.1-9.432.5-35.6000112.2
484L94.1Very high90.1Very high13 Ų1355 Ų557%0.06830%0.3CS..PPolyproline II helixtrans-57.1141.6175.3-68.3173.6000112.5Y321 Y324 Y373 E481 Y486 T495 I499Y321-L484 HydrophobicContact CD1-CD1 3.86Å; Y321-L484 HydrophobicContact CE1-CD1 3.84Å; Y324-L484 HydrophobicContact CD1-CD1 3.86Å; Y324-L484 HydrophobicContact CD1-CG 4.4Å; Y324-L484 HydrophobicContact CD2-CD1 4.07Å; Y324-L484 HydrophobicContact CD2-CD2 4.09Å; Y324-L484 HydrophobicContact CD2-CG 4.11Å; Y324-L484 HydrophobicContact CE1-CD1 3.88Å; Y324-L484 HydrophobicContact CE1-CG 4Å; Y324-L484 HydrophobicContact CE2-CD1 4.08Å; Y324-L484 HydrophobicContact CE2-CD2 3.8Å; Y324-L484 HydrophobicContact CE2-CG 3.67Å; Y324-L484 HydrophobicContact CG-CD1 3.96Å; Y324-L484 HydrophobicContact CG-CG 4.46Å; Y373-L484 HydrophobicContact CE1-CD1 4.31Å; E481-L484 HydrophobicContact CB-CD2 4.47Å; E481-L484 WeakPolarHBondContact O-CD2 3.42Å; E481-L484 PolarHBondContact O-N 2.81Å; L484-Y486 HydrophobicContact CB-CE1 4.3Å; L484-T495 HydrophobicContact CD1-CG2 4.3Å; L484-T495 HydrophobicContact CD2-CG2 4.4Å; L484-I499 HydrophobicContact CD1-CD1 4.08Å; L484-I499 HydrophobicContact CD1-CG1 4.49Å; L484-I499 HydrophobicContact CD2-CG1 4.04Å
485K92.3Very high89.8Confident129 Ų12955.6 Ų55.656%0.56130%0.304SS*.PPolyproline II helixtrans-97.5128.6169.4-66.2-175.3-169.5118.10111.2E481 T495 V496E481-K485 WeakPolarHBondContact OE1-CD 3.44Å; E481-K485 VanDerWaalsContact OE1-CE 3.24Å; E481-K485 WeakPolarHBondContact OE1-CE 3.46Å; E481-K485 VanDerWaalsContact OE1-CG 3.29Å; E481-K485 WeakPolarHBondContact OE1-CG 3.4Å; E481-K485 IonicContact OE1-NZ 2.69Å; E481-K485 PolarHBondContact OE1-NZ 2.75Å; K485-T495 CarbonylContact O-C 3.58Å; K485-T495 WeakPolarHBondContact O-CA 3.44Å; K485-V496 HydrophobicContact CB-CG2 4.29Å; K485-V496 PolarHBondContact O-N 2.74Å
486Y91.5Very high89.2Confident51 Ų5159.2 Ų59.220%0.233%0.325CS..BIsolated β-bridgetrans-98.7148179.3-51-76000112.8V51 Y321 Y373 L484 P488 L493 G494 T495 V496V51-Y486 WeakPolarHBondContact CG2-O 3.43Å; Y321-Y486 HydrophobicContact CE1-CE1 4.07Å; Y373-Y486 HydrophobicContact CD1-CE1 4.46Å; Y373-Y486 WeakPolarHBondContact CD1-OH 3.38Å; Y373-Y486 WeakPolarHBondContact CE1-OH 3.43Å; L484-Y486 HydrophobicContact CB-CE1 4.3Å; Y486-P488 WeakPolarHBondContact O-CD 3.49Å; Y486-L493 HydrophobicContact CD1-CD1 3.61Å; Y486-L493 HydrophobicContact CD1-CD2 4.49Å; Y486-L493 HydrophobicContact CD1-CG 3.8Å; Y486-L493 HydrophobicContact CD2-CD1 4.12Å; Y486-L493 HydrophobicContact CE1-CD1 4Å; Y486-L493 HydrophobicContact CE1-CD2 4.11Å; Y486-L493 HydrophobicContact CE1-CG 3.9Å; Y486-L493 HydrophobicContact CE2-CD1 4.47Å; Y486-L493 HydrophobicContact CG-CD1 3.67Å; Y486-L493 HydrophobicContact CG-CG 4.37Å; Y486-G494 CarbonylContact C-O 3.57Å; Y486-G494 VanDerWaalsContact CA-O 3.28Å; Y486-G494 WeakPolarHBondContact CA-O 3.44Å; Y486-G494 WeakPolarHBondContact CB-O 3.29Å; Y486-T495 HydrophobicContact CD1-CG2 4.42Å; Y486-V496 WeakPolarHBondContact O-CG2 3.33Å
487S86.8Confident88.7Confident29 Ų2958.1 Ų58.120%0.20333%0.326CS..PPolyproline II helixtrans-75.3121178.6177.20000110.6M489 S490 G494S487-M489 PolarHBondContact O-N 2.86Å; S487-M489 PolarHBondContact OG-N 2.91Å; S487-S490 PolarHBondContact O-N 3Å; S487-G494 PolarHBondContact N-O 2.69Å
488P80.6Confident88.5Confident29 Ų2958.3 Ų58.319%0.18833%0.331CS..THydrogen-bonded Turntrans-74.6-8.9177.631.5-36.3000113.4N49 Y486N49-P488 VanDerWaalsContact C-CB 3.43Å; N49-P488 HydrophobicContact CB-CB 4.33Å; N49-P488 HydrophobicContact CB-CG 3.94Å; N49-P488 VanDerWaalsContact O-CB 3.27Å; N49-P488 WeakPolarHBondContact O-CB 3.21Å; Y486-P488 WeakPolarHBondContact O-CD 3.49Å
489M70.5Confident88.5Confident103 Ų10350.5 Ų50.551%0.50729%0.288SS..THydrogen-bonded Turntrans-97.2-11.4179.1-63.3-166.2-66.100112.8K221 S487K221-M489 WeakPolarHBondContact CE-SD 3.33Å; K221-M489 PolarHBondContact NZ-SD 3.36Å; S487-M489 PolarHBondContact O-N 2.86Å; S487-M489 PolarHBondContact OG-N 2.91Å
490S75.1Confident88.7Confident24 Ų2450.9 Ų50.917%0.16828%0.281CS..  trans-77.6137-179.3-176.20000110.9S487 V492S487-S490 PolarHBondContact O-N 3Å; S490-V492 VanDerWaalsContact C-N 3.32Å; S490-V492 WeakPolarHBondContact CB-O 3.37Å; S490-V492 PolarHBondContact OG-N 3.4Å; S490-V492 PolarHBondContact OG-O 3.32Å
491I73.8Confident88.7Confident120 Ų12050.1 Ų50.162%0.61528%0.276SS*.SBendtrans-74.1-30.3175.3-60.2173.8000110.5
492V86.6Confident88.7Confident19 Ų1950.4 Ų50.412%0.11528%0.275CS..SBendtrans-101.6163.3171.2-63.20000110.6F214 E313 L375 V376 S490 G494F214-V492 HydrophobicContact CD1-CG2 4.33Å; F214-V492 HydrophobicContact CE1-CG1 4.47Å; F214-V492 HydrophobicContact CE1-CG2 4.26Å; E313-V492 HydrophobicContact CG-CG2 4.4Å; L375-V492 CarbonylContact O-C 3.32Å; L375-V492 WeakPolarHBondContact O-CA 3.47Å; L375-V492 WeakPolarHBondContact O-CB 3.12Å; V376-V492 HydrophobicContact CG2-CG1 4.43Å; S490-V492 VanDerWaalsContact C-N 3.32Å; S490-V492 WeakPolarHBondContact CB-O 3.37Å; S490-V492 PolarHBondContact OG-N 3.4Å; S490-V492 PolarHBondContact OG-O 3.32Å; V492-G494 VanDerWaalsContact C-N 3.32Å; V492-G494 PolarHBondContact O-N 3.5Å
493L90.6Very high88.8Confident7 Ų746.2 Ų46.24%0.03725%0.253CS..  trans-67.489.9173.1-171.269.3000110.3V51 H53 Y321 Y373 L375 Y486V51-L493 HydrophobicContact CG1-CD1 4.03Å; H53-L493 HydrophobicContact CB-CD1 4.43Å; Y321-L493 PolarHBondContact OH-O 3.44Å; Y373-L493 HydrophobicContact CD1-CD2 4.21Å; L375-L493 HydrophobicContact CD2-CB 4.38Å; L375-L493 PolarHBondContact O-N 2.94Å; Y486-L493 HydrophobicContact CD1-CD1 3.61Å; Y486-L493 HydrophobicContact CD1-CD2 4.49Å; Y486-L493 HydrophobicContact CD1-CG 3.8Å; Y486-L493 HydrophobicContact CD2-CD1 4.12Å; Y486-L493 HydrophobicContact CE1-CD1 4Å; Y486-L493 HydrophobicContact CE1-CD2 4.11Å; Y486-L493 HydrophobicContact CE1-CG 3.9Å; Y486-L493 HydrophobicContact CE2-CD1 4.47Å; Y486-L493 HydrophobicContact CG-CD1 3.67Å; Y486-L493 HydrophobicContact CG-CG 4.37Å
494G88.2Confident88.9Confident3 Ų343.8 Ų43.83%0.03123%0.233CC..  trans-112.9148177.700000111.5Y486 S487 V492Y486-G494 CarbonylContact C-O 3.57Å; Y486-G494 VanDerWaalsContact CA-O 3.28Å; Y486-G494 WeakPolarHBondContact CA-O 3.44Å; Y486-G494 WeakPolarHBondContact CB-O 3.29Å; S487-G494 PolarHBondContact N-O 2.69Å; V492-G494 VanDerWaalsContact C-N 3.32Å; V492-G494 PolarHBondContact O-N 3.5Å
495T90.4Very high88.8Confident12 Ų1248 Ų487%0.07425%0.248CC..BIsolated β-bridgetrans-75152.3174.751.50000112.9K176 Y321 L484 K485 Y486 G497 I499K176-T495 PolarHBondContact NZ-OG1 2.6Å; Y321-T495 HydrophobicContact CE1-CG2 3.85Å; L484-T495 HydrophobicContact CD1-CG2 4.3Å; L484-T495 HydrophobicContact CD2-CG2 4.4Å; K485-T495 CarbonylContact O-C 3.58Å; K485-T495 WeakPolarHBondContact O-CA 3.44Å; Y486-T495 HydrophobicContact CD1-CG2 4.42Å; T495-G497 WeakPolarHBondContact CB-O 3.31Å; T495-G497 PolarHBondContact OG1-O 3.38Å; T495-I499 HydrophobicContact CG2-CD1 4.18Å; T495-I499 HydrophobicContact CG2-CG1 4.2Å
496V86.1Confident88.6Confident101 Ų10148 Ų4861%0.61225%0.253SS*.SBendtrans-68.2-36.4172.2175.60000111.2K485 Y486K485-V496 HydrophobicContact CB-CG2 4.29Å; K485-V496 PolarHBondContact O-N 2.74Å; Y486-V496 WeakPolarHBondContact O-CG2 3.33Å
497G86.3Confident88.4Confident38 Ų3847.9 Ų47.939%0.39226%0.255SS..SBendtrans-118.4-166.9175.800000113T495T495-G497 WeakPolarHBondContact CB-O 3.31Å; T495-G497 PolarHBondContact OG1-O 3.38Å
498G91.4Very high88.5Confident20 Ų2048.9 Ų48.921%0.20626%0.258CS..  trans-75.3172.5169.300000113E174E174-G498 WeakPolarHBondContact OE1-CA 3.37Å
499I97.1Very high88.9Confident2 Ų250 Ų501%0.0126%0.262CS..  trans-109.3107.4169.4-64.7174.7000107.1E174 I175 Y321 Y324 L484 T495 L501E174-I499 CarbonylContact C-O 3.57Å; E174-I499 PolarHBondContact OE1-N 3.03Å; I175-I499 HydrophobicContact CB-CG2 4.48Å; I175-I499 WeakPolarHBondContact CB-O 3.26Å; I175-I499 PolarHBondContact N-O 3.5Å; Y321-I499 HydrophobicContact CD1-CD1 3.84Å; Y321-I499 HydrophobicContact CE1-CD1 3.87Å; Y324-I499 HydrophobicContact CD2-CG2 4.22Å; L484-I499 HydrophobicContact CD1-CD1 4.08Å; L484-I499 HydrophobicContact CD1-CG1 4.49Å; L484-I499 HydrophobicContact CD2-CG1 4.04Å; T495-I499 HydrophobicContact CG2-CD1 4.18Å; T495-I499 HydrophobicContact CG2-CG1 4.2Å; I499-L501 HydrophobicContact CG2-CD1 4.32Å; I499-L501 HydrophobicContact CG2-CD2 4.5Å; I499-L501 HydrophobicContact CG2-CG 4.15Å
500Y97.9Very high90Very high96 Ų9646.9 Ų46.938%0.37625%0.248SC..EExtended strand (participates in β ladder)trans-98.6124.2-178.9-63-92.7000110.1V172 L173 E174 T479 T480V172-Y500 HydrophobicContact CG1-CD1 4.41Å; L173-Y500 WeakPolarHBondContact O-CA 3.28Å; E174-Y500 HydrophobicContact CB-CD1 3.87Å; E174-Y500 HydrophobicContact CB-CE1 3.57Å; E174-Y500 HydrophobicContact CG-CD1 3.9Å; E174-Y500 HydrophobicContact CG-CD2 4.42Å; E174-Y500 HydrophobicContact CG-CE1 3.42Å; E174-Y500 VanDerWaalsContact CG-CE1 3.42Å; E174-Y500 HydrophobicContact CG-CE2 3.98Å; E174-Y500 HydrophobicContact CG-CG 4.38Å; E174-Y500 VanDerWaalsContact CG-CZ 3.46Å; T479-Y500 HydrophobicContact CG2-CD1 4.44Å; T479-Y500 HydrophobicContact CG2-CD2 3.94Å; T479-Y500 HydrophobicContact CG2-CG 3.89Å; T480-Y500 WeakPolarHBondContact CB-O 3.47Å; T480-Y500 PolarHBondContact OG1-O 2.92Å
501L97.8Very high91Very high0 Ų048.3 Ų48.30%025%0.253CS..EExtended strand (participates in β ladder)trans-131.9152.7177.2-59176.6000110V172 L173 I175 L323 A327 V474 T480 I499V172-L501 WeakPolarHBondContact CA-O 3.29Å; L173-L501 PolarHBondContact N-O 3Å; L173-L501 PolarHBondContact O-N 3.03Å; I175-L501 HydrophobicContact CD1-CB 4.33Å; I175-L501 HydrophobicContact CG1-CB 3.81Å; I175-L501 HydrophobicContact CG1-CD1 3.86Å; I175-L501 HydrophobicContact CG1-CG 3.88Å; L323-L501 HydrophobicContact CB-CD1 4.04Å; L323-L501 WeakPolarHBondContact O-CD1 3.24Å; A327-L501 HydrophobicContact CB-CD1 4.02Å; A327-L501 HydrophobicContact CB-CD2 3.77Å; A327-L501 HydrophobicContact CB-CG 4.47Å; V474-L501 HydrophobicContact CG1-CB 3.6Å; V474-L501 HydrophobicContact CG1-CD1 3.44Å; V474-L501 VanDerWaalsContact CG1-CD1 3.44Å; V474-L501 HydrophobicContact CG1-CG 4.08Å; T480-L501 HydrophobicContact CG2-CD2 3.77Å; I499-L501 HydrophobicContact CG2-CD1 4.32Å; I499-L501 HydrophobicContact CG2-CD2 4.5Å; I499-L501 HydrophobicContact CG2-CG 4.15Å
502R96.8Very high92.1Very high64 Ų6443.5 Ų43.524%0.24223%0.228CC..EExtended strand (participates in β ladder)trans-80.2133.1168.2-178.3174.1-57.7-81.6-2.5108.8N169 V474 S475 C477 E504N169-R502 PolarHBondContact O-NH1 3.06Å; V474-R502 CarbonylContact C-O 3.51Å; V474-R502 VanDerWaalsContact CA-O 3.31Å; V474-R502 WeakPolarHBondContact CA-O 3.42Å; S475-R502 PolarHBondContact N-O 2.84Å; S475-R502 PolarHBondContact O-N 2.8Å; C477-R502 HydrophobicContact CB-CB 4.15Å; R502-E504 WeakPolarHBondContact CD-OE1 3.19Å; R502-E504 HydrophobicContact CG-CG 4.26Å
503V97.3Very high92.5Very high3 Ų345.3 Ų45.32%0.01824%0.236CC..EExtended strand (participates in β ladder)trans-123.1124.2178.9-174.50000108.4I160 V164 G170 A171 L173 I175 F472 R473 V474I160-V503 HydrophobicContact CG2-CG1 4.3Å; V164-V503 WeakPolarHBondContact CG1-O 3.27Å; V164-V503 HydrophobicContact CG2-CB 4.05Å; V164-V503 HydrophobicContact CG2-CG1 3.96Å; G170-V503 CarbonylContact C-O 3.55Å; G170-V503 WeakPolarHBondContact CA-O 3.24Å; A171-V503 PolarHBondContact N-O 3.45Å; A171-V503 PolarHBondContact O-N 2.96Å; L173-V503 HydrophobicContact CB-CG2 4.27Å; L173-V503 HydrophobicContact CD1-CB 4.14Å; L173-V503 HydrophobicContact CD1-CG2 3.92Å; L173-V503 HydrophobicContact CG-CB 4.4Å; L173-V503 HydrophobicContact CG-CG2 4.1Å; I175-V503 HydrophobicContact CD1-CG2 3.96Å; F472-V503 HydrophobicContact CB-CG1 3.72Å; F472-V503 HydrophobicContact CD1-CG1 3.74Å; F472-V503 HydrophobicContact CG-CG1 3.89Å; R473-V503 WeakPolarHBondContact O-CA 3.41Å; V474-V503 HydrophobicContact CG2-CG2 4.4Å
504E95Very high92.6Very high56 Ų5648.2 Ų48.226%0.26225%0.252SS..EExtended strand (participates in β ladder)trans-122136.9-177.5-71.4166-174.700109.3F472 R473 R502F472-E504 CarbonylContact C-O 3.56Å; F472-E504 WeakPolarHBondContact CA-O 3.09Å; F472-E504 WeakPolarHBondContact CB-O 3.37Å; R473-E504 HydrophobicContact CB-CB 4.43Å; R473-E504 PolarHBondContact N-O 2.84Å; R473-E504 PolarHBondContact O-N 3.05Å; R502-E504 WeakPolarHBondContact CD-OE1 3.19Å; R502-E504 HydrophobicContact CG-CG 4.26Å
505R92.1Very high93Very high103 Ų10352 Ų5239%0.38927%0.27SS..EExtended strand (participates in β ladder)trans-72.9140.8171.1-65.1-172-165.3179.514.6109.4T161 V164 F472T161-R505 VanDerWaalsContact C-NH2 3.32Å; T161-R505 VanDerWaalsContact CG2-NH2 3.33Å; T161-R505 PolarHBondContact O-NH2 2.86Å; V164-R505 HydrophobicContact CB-CG 4.49Å; V164-R505 HydrophobicContact CG1-CG 3.99Å; V164-R505 PolarHBondContact O-NE 3Å; V164-R505 PolarHBondContact O-NH2 2.84Å; F472-R505 HydrophobicContact CD1-CG 3.96Å; F472-R505 HydrophobicContact CE1-CG 3.68Å
506I87.9Confident93.2Very high129 Ų12955.6 Ų55.666%0.66229%0.288SS*.  trans-110.10174.751.1168.2000111.9R337 R471 R473R337-I506 VanDerWaalsContact CD-CD1 3.5Å; R471-I506 VanDerWaalsContact O-CG1 3.28Å; R471-I506 WeakPolarHBondContact O-CG1 3.42Å; R471-I506 PolarHBondContact O-N 3.46Å; R473-I506 HydrophobicContact CB-CG2 3.99Å

Retrieved 506 of 506 residues in 674.8 ms (Link to these results)