A0A075BRU8_DROME Loading...

Cytochrome P450

AlphaFold DB , UniProt , Accession A0A075BRU8, Species DROME (Drosophila melanogaster, Fruit fly), Gene Cyp6a2, Length 506 aa.

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Site Residue pLDDT pLDDT confidence pLDDT10 pLDDT10 confidence SASA SASA [Ų] SASA10 SASA10 [Ų] RSA RSA unformatted RSA10 RSA10 unformatted Surface Surface10 (not used) Disorder (not used) Disorder Sec. str. Secondary structure Isomer Phi (φ) Psi (ψ) Omega (ω) Chi 1 (χ1) Chi 2 (χ2) Chi 3 (χ3) Chi 4 (χ4) Chi 5 (χ5) Tau (τ) Contacts (colored by PAE) Contact details
1M73.1Confident90.1Very high171 Ų171113.1 Ų113.184%0.84258%0.579SS**  0-58.40-161.9165.968.100112V3 L4 I5M1-V3 PolarHBondContact O-N 3.26Å; M1-L4 PolarHBondContact O-N 2.98Å; M1-I5 HydrophobicContact CG-CD1 4.27Å; M1-I5 PolarHBondContact O-N 2.91Å
2F86.3Confident90.2Very high142 Ų142108.5 Ų108.562%0.62356%0.564SS**Hα-helixtrans-58.3-40179.7-66.3-75.8000115L4 I5 Y6F2-L4 VanDerWaalsContact C-N 3.33Å; F2-L4 PolarHBondContact O-N 3.17Å; F2-I5 PolarHBondContact O-N 2.75Å; F2-I5 VanDerWaalsContact O-N 3.15Å; F2-Y6 HydrophobicContact CB-CD2 4.37Å; F2-Y6 HydrophobicContact CB-CE2 4.08Å; F2-Y6 WeakPolarHBondContact O-CD2 3.36Å; F2-Y6 PolarHBondContact O-N 2.74Å
3V89.2Confident90.3Very high105 Ų105105.3 Ų105.364%0.63656%0.557SS**Hα-helixtrans-60-40.5176.7177.90000112.4M1 I5 Y6 L7M1-V3 PolarHBondContact O-N 3.26Å; V3-I5 VanDerWaalsContact C-N 3.34Å; V3-Y6 PolarHBondContact O-N 2.8Å; V3-L7 HydrophobicContact CG1-CD1 4.1Å; V3-L7 WeakPolarHBondContact O-CB 3.34Å; V3-L7 WeakPolarHBondContact O-CG 3.34Å; V3-L7 PolarHBondContact O-N 3.02Å
4L89.8Confident90.4Very high124 Ų124104.9 Ų104.965%0.64956%0.555SS**Hα-helixtrans-67.4-37.1177-69.4170.6000111.5M1 F2 L8M1-L4 PolarHBondContact O-N 2.98Å; F2-L4 VanDerWaalsContact C-N 3.33Å; F2-L4 PolarHBondContact O-N 3.17Å; L4-L8 WeakPolarHBondContact O-CB 3.42Å; L4-L8 PolarHBondContact O-N 2.86Å
5I92.6Very high90.3Very high80 Ų80105 Ų10541%0.4156%0.555SS.*Hα-helixtrans-65.7-46.6175.9-64.2169.6000110.3M1 F2 V3 L7 L8 I9M1-I5 HydrophobicContact CG-CD1 4.27Å; M1-I5 PolarHBondContact O-N 2.91Å; F2-I5 PolarHBondContact O-N 2.75Å; F2-I5 VanDerWaalsContact O-N 3.15Å; V3-I5 VanDerWaalsContact C-N 3.34Å; I5-L7 PolarHBondContact O-N 2.81Å; I5-L8 PolarHBondContact O-N 2.92Å; I5-I9 HydrophobicContact CG2-CD1 3.83Å; I5-I9 VanDerWaalsContact O-CG1 3.32Å; I5-I9 WeakPolarHBondContact O-CG1 3.17Å; I5-I9 PolarHBondContact O-N 3.36Å
6Y93.7Very high90.2Very high159 Ų159102 Ų10262%0.62455%0.549SS*.Hα-helixtrans-63.1-40.7176.7-71.3-60.1000112.6F2 V3 L8 I9 A10F2-Y6 HydrophobicContact CB-CD2 4.37Å; F2-Y6 HydrophobicContact CB-CE2 4.08Å; F2-Y6 WeakPolarHBondContact O-CD2 3.36Å; F2-Y6 PolarHBondContact O-N 2.74Å; V3-Y6 PolarHBondContact O-N 2.8Å; Y6-L8 VanDerWaalsContact C-N 3.35Å; Y6-I9 PolarHBondContact O-N 2.68Å; Y6-A10 VanDerWaalsContact O-CB 3.31Å; Y6-A10 WeakPolarHBondContact O-CB 3.42Å; Y6-A10 PolarHBondContact O-N 3.23Å
7L92.8Very high90.2Very high95 Ų95103.8 Ų103.850%0.49755%0.548SS..Hα-helixtrans-61.7-43.6174-78.7169.2000111.5V3 I5 A10 I11V3-L7 HydrophobicContact CG1-CD1 4.1Å; V3-L7 WeakPolarHBondContact O-CB 3.34Å; V3-L7 WeakPolarHBondContact O-CG 3.34Å; V3-L7 PolarHBondContact O-N 3.02Å; I5-L7 PolarHBondContact O-N 2.81Å; L7-A10 PolarHBondContact O-N 2.62Å; L7-I11 WeakPolarHBondContact O-CB 3.26Å; L7-I11 WeakPolarHBondContact O-CD1 3.29Å; L7-I11 WeakPolarHBondContact O-CG1 3.44Å; L7-I11 PolarHBondContact O-N 3.25Å
8L93.3Very high90Very high125 Ų125102.7 Ų102.765%0.65454%0.542SS*.Hα-helixtrans-63.8-42.7178.6-166.4118.9000111.6L4 I5 Y6 I11 S12L4-L8 WeakPolarHBondContact O-CB 3.42Å; L4-L8 PolarHBondContact O-N 2.86Å; I5-L8 PolarHBondContact O-N 2.92Å; Y6-L8 VanDerWaalsContact C-N 3.35Å; L8-I11 PolarHBondContact O-N 2.6Å; L8-S12 WeakPolarHBondContact O-CB 3.31Å; L8-S12 PolarHBondContact O-N 2.97Å; L8-S12 PolarHBondContact O-OG 3.13Å
9I94.1Very high89.8Confident86 Ų86102.3 Ų102.344%0.44153%0.533SS..Hα-helixtrans-65.2-42.8176.1-67.4167.7000111.3I5 Y6 S12 S13I5-I9 HydrophobicContact CG2-CD1 3.83Å; I5-I9 VanDerWaalsContact O-CG1 3.32Å; I5-I9 WeakPolarHBondContact O-CG1 3.17Å; I5-I9 PolarHBondContact O-N 3.36Å; Y6-I9 PolarHBondContact O-N 2.68Å; I9-S12 WeakPolarHBondContact CA-OG 3.48Å; I9-S12 PolarHBondContact O-N 3.49Å; I9-S12 PolarHBondContact O-OG 2.87Å; I9-S13 VanDerWaalsContact O-CB 3.25Å; I9-S13 WeakPolarHBondContact O-CB 3.42Å; I9-S13 PolarHBondContact O-N 3.33Å; I9-S13 PolarHBondContact O-OG 3.28Å
10A93.3Very high89.7Confident59 Ų59103.1 Ų103.149%0.48853%0.533SS..Hα-helixtrans-63.9-44.317800000111.2Y6 L7 S13 L14Y6-A10 VanDerWaalsContact O-CB 3.31Å; Y6-A10 WeakPolarHBondContact O-CB 3.42Å; Y6-A10 PolarHBondContact O-N 3.23Å; L7-A10 PolarHBondContact O-N 2.62Å; A10-S13 PolarHBondContact O-N 2.89Å; A10-L14 VanDerWaalsContact O-CB 3.31Å; A10-L14 WeakPolarHBondContact O-CB 3.14Å; A10-L14 PolarHBondContact O-N 2.93Å
11I92.5Very high89.6Confident98 Ų98104.4 Ų104.450%0.50353%0.532SS..Hα-helixtrans-64-46.7175.8-69166.4000110.4L7 L8 S13 L14 L15L7-I11 WeakPolarHBondContact O-CB 3.26Å; L7-I11 WeakPolarHBondContact O-CD1 3.29Å; L7-I11 WeakPolarHBondContact O-CG1 3.44Å; L7-I11 PolarHBondContact O-N 3.25Å; L8-I11 PolarHBondContact O-N 2.6Å; I11-S13 VanDerWaalsContact C-N 3.34Å; I11-S13 PolarHBondContact O-N 2.9Å; I11-L14 PolarHBondContact O-N 3.1Å; I11-L15 HydrophobicContact CG2-CD1 3.81Å; I11-L15 HydrophobicContact CG2-CG 4.26Å; I11-L15 WeakPolarHBondContact O-CB 3.36Å; I11-L15 VanDerWaalsContact O-CG 3.23Å; I11-L15 WeakPolarHBondContact O-CG 3.43Å; I11-L15 PolarHBondContact O-N 3.18Å
12S91.3Very high90.3Very high58 Ų5898.5 Ų98.541%0.40650%0.504SS..Hα-helixtrans-64-39.6-179.967.60000111.9L8 I9 L15 A16L8-S12 WeakPolarHBondContact O-CB 3.31Å; L8-S12 PolarHBondContact O-N 2.97Å; L8-S12 PolarHBondContact O-OG 3.13Å; I9-S12 WeakPolarHBondContact CA-OG 3.48Å; I9-S12 PolarHBondContact O-N 3.49Å; I9-S12 PolarHBondContact O-OG 2.87Å; S12-L15 PolarHBondContact O-N 3.21Å; S12-A16 VanDerWaalsContact O-CB 3.31Å; S12-A16 WeakPolarHBondContact O-CB 3.49Å; S12-A16 PolarHBondContact O-N 3.18Å
13S92.5Very high90.5Very high67 Ų6792.6 Ų92.647%0.46948%0.477SS..Hα-helixtrans-67.5-42.2177.1-56.70000111.5I9 A10 I11 A16 Y17I9-S13 VanDerWaalsContact O-CB 3.25Å; I9-S13 WeakPolarHBondContact O-CB 3.42Å; I9-S13 PolarHBondContact O-N 3.33Å; I9-S13 PolarHBondContact O-OG 3.28Å; A10-S13 PolarHBondContact O-N 2.89Å; I11-S13 VanDerWaalsContact C-N 3.34Å; I11-S13 PolarHBondContact O-N 2.9Å; S13-A16 PolarHBondContact O-N 3.09Å; S13-Y17 WeakPolarHBondContact O-CB 3.13Å; S13-Y17 PolarHBondContact O-N 2.69Å
14L91.9Very high90.6Very high100 Ų10089.7 Ų89.752%0.52446%0.458SS..Hα-helixtrans-62.2-45173.9178.162.8000111.2A10 I11 Y17 L18A10-L14 VanDerWaalsContact O-CB 3.31Å; A10-L14 WeakPolarHBondContact O-CB 3.14Å; A10-L14 PolarHBondContact O-N 2.93Å; I11-L14 PolarHBondContact O-N 3.1Å; L14-Y17 PolarHBondContact O-N 3.15Å; L14-L18 HydrophobicContact CD1-CD1 4.2Å; L14-L18 HydrophobicContact CD1-CG 4.18Å; L14-L18 HydrophobicContact CG-CD1 4.1Å; L14-L18 HydrophobicContact CG-CG 4.46Å; L14-L18 WeakPolarHBondContact O-CB 3.38Å; L14-L18 VanDerWaalsContact O-CG 3.26Å; L14-L18 WeakPolarHBondContact O-CG 3.2Å; L14-L18 PolarHBondContact O-N 3.44Å
15L87.9Confident90.9Very high106 Ų10684.8 Ų84.856%0.55543%0.431SS*.Hα-helixtrans-62.6-43.8176.7-72173.6000111.5I11 S12 L18 Y19I11-L15 HydrophobicContact CG2-CD1 3.81Å; I11-L15 HydrophobicContact CG2-CG 4.26Å; I11-L15 WeakPolarHBondContact O-CB 3.36Å; I11-L15 VanDerWaalsContact O-CG 3.23Å; I11-L15 WeakPolarHBondContact O-CG 3.43Å; I11-L15 PolarHBondContact O-N 3.18Å; S12-L15 PolarHBondContact O-N 3.21Å; L15-L18 PolarHBondContact O-N 2.86Å; L15-Y19 WeakPolarHBondContact O-CB 3.33Å; L15-Y19 PolarHBondContact O-N 2.83Å
16A88.9Confident91.1Very high57 Ų5781 Ų8147%0.47141%0.412SS..Hα-helixtrans-62.7-42.2176.100000111.9S12 S13 Y19 H20S12-A16 VanDerWaalsContact O-CB 3.31Å; S12-A16 WeakPolarHBondContact O-CB 3.49Å; S12-A16 PolarHBondContact O-N 3.18Å; S13-A16 PolarHBondContact O-N 3.09Å; A16-Y19 PolarHBondContact O-N 3.43Å; A16-H20 VanDerWaalsContact O-CB 3.28Å; A16-H20 WeakPolarHBondContact O-CB 3.3Å; A16-H20 PolarHBondContact O-N 3.35Å
17Y90.4Very high91.1Very high133 Ų13378.3 Ų78.352%0.52241%0.408SS..Hα-helixtrans-63.8-47.6175.3171.7-106.1000112S13 L14 Y19 H20 R21S13-Y17 WeakPolarHBondContact O-CB 3.13Å; S13-Y17 PolarHBondContact O-N 2.69Å; L14-Y17 PolarHBondContact O-N 3.15Å; Y17-Y19 VanDerWaalsContact C-N 3.32Å; Y17-Y19 PolarHBondContact O-N 3.46Å; Y17-H20 PolarHBondContact O-N 2.83Å; Y17-R21 WeakPolarHBondContact O-CB 3.37Å; Y17-R21 PolarHBondContact O-N 2.91Å
18L86.7Confident91.2Very high84 Ų8479.8 Ų79.844%0.4441%0.407SS..Hα-helixtrans-62.6-42177.7-71176000111.4L14 L15 R21 N22L14-L18 HydrophobicContact CD1-CD1 4.2Å; L14-L18 HydrophobicContact CD1-CG 4.18Å; L14-L18 HydrophobicContact CG-CD1 4.1Å; L14-L18 HydrophobicContact CG-CG 4.46Å; L14-L18 WeakPolarHBondContact O-CB 3.38Å; L14-L18 VanDerWaalsContact O-CG 3.26Å; L14-L18 WeakPolarHBondContact O-CG 3.2Å; L14-L18 PolarHBondContact O-N 3.44Å; L15-L18 PolarHBondContact O-N 2.86Å; L18-R21 PolarHBondContact O-N 3.42Å; L18-N22 WeakPolarHBondContact O-CB 3.19Å; L18-N22 PolarHBondContact O-N 3.24Å
19Y86.2Confident91.2Very high94 Ų9477.3 Ų77.337%0.36939%0.389SS..Hα-helixtrans-60.2-53.2175.6175.4-93.9000111.2L15 A16 Y17 R21 N22 F23 P38L15-Y19 WeakPolarHBondContact O-CB 3.33Å; L15-Y19 PolarHBondContact O-N 2.83Å; A16-Y19 PolarHBondContact O-N 3.43Å; Y17-Y19 VanDerWaalsContact C-N 3.32Å; Y17-Y19 PolarHBondContact O-N 3.46Å; Y19-R21 PolarHBondContact O-N 2.81Å; Y19-N22 PolarHBondContact O-N 3.34Å; Y19-F23 AromaticContact CD2-CD2 3.99Å; Y19-F23 HydrophobicContact CD2-CD2 3.99Å; Y19-F23 AromaticContact CD2-CE2 3.83Å; Y19-F23 HydrophobicContact CD2-CE2 3.83Å; Y19-F23 HydrophobicContact CD2-CZ 4.32Å; Y19-F23 HydrophobicContact CE1-CD1 4.33Å; Y19-F23 HydrophobicContact CE1-CG 4.36Å; Y19-F23 AromaticContact CE2-CD1 4Å; Y19-F23 HydrophobicContact CE2-CD1 4Å; Y19-F23 AromaticContact CE2-CD2 3.75Å; Y19-F23 HydrophobicContact CE2-CD2 3.75Å; Y19-F23 AromaticContact CE2-CE1 3.75Å; Y19-F23 HydrophobicContact CE2-CE1 3.75Å; Y19-F23 AromaticContact CE2-CE2 3.41Å; Y19-F23 HydrophobicContact CE2-CE2 3.41Å; Y19-F23 VanDerWaalsContact CE2-CE2 3.41Å; Y19-F23 HydrophobicContact CE2-CG 4.08Å; Y19-F23 AromaticContact CE2-CZ 3.46Å; Y19-F23 HydrophobicContact CE2-CZ 3.46Å; Y19-F23 VanDerWaalsContact CE2-CZ 3.46Å; Y19-F23 AromaticContact CZ-CD1 3.64Å; Y19-F23 AromaticContact CZ-CE1 3.7Å; Y19-F23 AromaticContact CZ-CG 3.93Å; Y19-F23 AromaticContact CZ-CZ 3.93Å; Y19-F23 WeakPolarHBondContact O-CB 3.48Å; Y19-F23 WeakPolarHBondContact O-CD2 3.31Å; Y19-F23 PolarHBondContact O-N 2.97Å; Y19-F23 VanDerWaalsContact OH-CD1 3.25Å; Y19-F23 WeakPolarHBondContact OH-CD1 3.4Å; Y19-F23 WeakPolarHBondContact OH-CE1 3.35Å; Y19-P38 WeakPolarHBondContact OH-CA 3.35Å; Y19-P38 WeakPolarHBondContact OH-CB 3.35Å
20H87.7Confident91.2Very high118 Ų11875.9 Ų75.955%0.54640%0.395SS..Hα-helixtrans-61.6-42.9178.1-175.381.3000111.9A16 Y17 N22 F23 N24A16-H20 VanDerWaalsContact O-CB 3.28Å; A16-H20 WeakPolarHBondContact O-CB 3.3Å; A16-H20 PolarHBondContact O-N 3.35Å; Y17-H20 PolarHBondContact O-N 2.83Å; H20-N22 VanDerWaalsContact C-N 3.28Å; H20-N22 PolarHBondContact O-N 3.29Å; H20-F23 PolarHBondContact O-N 3.34Å; H20-N24 PolarHBondContact CE1-ND2 3.21Å; H20-N24 PolarHBondContact ND1-ND2 2.79Å; H20-N24 PolarHBondContact NE2-ND2 3.37Å; H20-N24 WeakPolarHBondContact O-CB 3.39Å; H20-N24 PolarHBondContact O-N 2.9Å
21R88.1Confident91.4Very high132 Ų13273.3 Ų73.350%0.49837%0.374SS..Hα-helixtrans-59.6-42.1176.4-178.4176.4175.6179.60.4110.9Y17 L18 Y19 Y25 R28Y17-R21 WeakPolarHBondContact O-CB 3.37Å; Y17-R21 PolarHBondContact O-N 2.91Å; L18-R21 PolarHBondContact O-N 3.42Å; Y19-R21 PolarHBondContact O-N 2.81Å; R21-Y25 PolarHBondContact O-N 2.89Å; R21-R28 VanDerWaalsContact O-CZ 3.22Å; R21-R28 PolarHBondContact O-NH1 3.1Å; R21-R28 PolarHBondContact O-NH2 3.15Å
22N88Confident91.6Very high47 Ų4770.3 Ų70.325%0.25136%0.361SS..Hα-helixtrans-73.9-42.5-177.4-175.963.3000112.2L18 Y19 H20 N24 Y25 Y74 H77 P79L18-N22 WeakPolarHBondContact O-CB 3.19Å; L18-N22 PolarHBondContact O-N 3.24Å; Y19-N22 PolarHBondContact O-N 3.34Å; H20-N22 VanDerWaalsContact C-N 3.28Å; H20-N22 PolarHBondContact O-N 3.29Å; N22-N24 VanDerWaalsContact C-N 3.25Å; N22-N24 PolarHBondContact O-N 2.86Å; N22-Y25 WeakPolarHBondContact O-CB 3.46Å; N22-Y25 PolarHBondContact O-N 2.92Å; N22-Y25 VanDerWaalsContact O-N 3.07Å; N22-Y74 VanDerWaalsContact O-CE1 3.29Å; N22-Y74 WeakPolarHBondContact O-CE1 3.2Å; N22-Y74 PolarHBondContact O-OH 3.4Å; N22-H77 PolarHBondContact ND2-O 2.92Å; N22-P79 WeakPolarHBondContact OD1-CD 3.49Å
23F89.6Confident91.8Very high17 Ų1769.5 Ų69.58%0.07535%0.35CS..Hα-helixtrans-73.3-16.3179.3-81.1-128.6000113Y19 H20 P36 Y74 H77Y19-F23 AromaticContact CD2-CD2 3.99Å; Y19-F23 HydrophobicContact CD2-CD2 3.99Å; Y19-F23 AromaticContact CD2-CE2 3.83Å; Y19-F23 HydrophobicContact CD2-CE2 3.83Å; Y19-F23 HydrophobicContact CD2-CZ 4.32Å; Y19-F23 HydrophobicContact CE1-CD1 4.33Å; Y19-F23 HydrophobicContact CE1-CG 4.36Å; Y19-F23 AromaticContact CE2-CD1 4Å; Y19-F23 HydrophobicContact CE2-CD1 4Å; Y19-F23 AromaticContact CE2-CD2 3.75Å; Y19-F23 HydrophobicContact CE2-CD2 3.75Å; Y19-F23 AromaticContact CE2-CE1 3.75Å; Y19-F23 HydrophobicContact CE2-CE1 3.75Å; Y19-F23 AromaticContact CE2-CE2 3.41Å; Y19-F23 HydrophobicContact CE2-CE2 3.41Å; Y19-F23 VanDerWaalsContact CE2-CE2 3.41Å; Y19-F23 HydrophobicContact CE2-CG 4.08Å; Y19-F23 AromaticContact CE2-CZ 3.46Å; Y19-F23 HydrophobicContact CE2-CZ 3.46Å; Y19-F23 VanDerWaalsContact CE2-CZ 3.46Å; Y19-F23 AromaticContact CZ-CD1 3.64Å; Y19-F23 AromaticContact CZ-CE1 3.7Å; Y19-F23 AromaticContact CZ-CG 3.93Å; Y19-F23 AromaticContact CZ-CZ 3.93Å; Y19-F23 WeakPolarHBondContact O-CB 3.48Å; Y19-F23 WeakPolarHBondContact O-CD2 3.31Å; Y19-F23 PolarHBondContact O-N 2.97Å; Y19-F23 VanDerWaalsContact OH-CD1 3.25Å; Y19-F23 WeakPolarHBondContact OH-CD1 3.4Å; Y19-F23 WeakPolarHBondContact OH-CE1 3.35Å; H20-F23 PolarHBondContact O-N 3.34Å; F23-P36 HydrophobicContact CB-CG 4.05Å; F23-P36 HydrophobicContact CD1-CB 3.75Å; F23-P36 HydrophobicContact CD1-CG 3.3Å; F23-P36 HydrophobicContact CE1-CB 3.68Å; F23-P36 HydrophobicContact CE1-CG 3.81Å; F23-P36 HydrophobicContact CG-CG 3.87Å; F23-Y74 VanDerWaalsContact C-OH 3.24Å; F23-Y74 PolarHBondContact O-OH 3.31Å; F23-H77 HydrophobicContact CE2-CB 3.93Å; F23-H77 HydrophobicContact CZ-CB 4.22Å
24N92.3Very high91.9Very high44 Ų4468.5 Ų68.524%0.23534%0.34CS..THydrogen-bonded Turntrans-96.712.4169-82.7-44.5000114.1H20 N22 W26 R28H20-N24 PolarHBondContact CE1-ND2 3.21Å; H20-N24 PolarHBondContact ND1-ND2 2.79Å; H20-N24 PolarHBondContact NE2-ND2 3.37Å; H20-N24 WeakPolarHBondContact O-CB 3.39Å; H20-N24 PolarHBondContact O-N 2.9Å; N22-N24 VanDerWaalsContact C-N 3.25Å; N22-N24 PolarHBondContact O-N 2.86Å; N24-W26 PolarHBondContact O-N 3.42Å; N24-R28 WeakPolarHBondContact O-CG 3.48Å; N24-R28 PolarHBondContact O-N 2.76Å; N24-R28 VanDerWaalsContact O-N 3.14Å
25Y95.3Very high91.9Very high21 Ų2168 Ų688%0.08235%0.35CS..THydrogen-bonded Turntrans-56.6-50.5-177.4175-87.3000112.7R21 N22 R29 Y74 P79 E398 T401R21-Y25 PolarHBondContact O-N 2.89Å; N22-Y25 WeakPolarHBondContact O-CB 3.46Å; N22-Y25 PolarHBondContact O-N 2.92Å; N22-Y25 VanDerWaalsContact O-N 3.07Å; Y25-R29 VanDerWaalsContact CZ-CZ 3.4Å; Y25-R29 VanDerWaalsContact CZ-NE 3.26Å; Y25-R29 PolarHBondContact O-NH1 3.04Å; Y25-R29 PolarHBondContact OH-NE 3.44Å; Y25-Y74 WeakPolarHBondContact CB-OH 3.45Å; Y25-Y74 PolarHBondContact N-OH 2.93Å; Y25-P79 HydrophobicContact CD1-CB 3.63Å; Y25-P79 HydrophobicContact CD1-CG 4.17Å; Y25-P79 HydrophobicContact CD2-CG 4.37Å; Y25-P79 HydrophobicContact CE1-CB 4.16Å; Y25-P79 HydrophobicContact CG-CB 3.96Å; Y25-P79 HydrophobicContact CG-CG 4.07Å; Y25-E398 WeakPolarHBondContact CE2-OE2 3.21Å; Y25-E398 VanDerWaalsContact CZ-OE2 3.31Å; Y25-E398 VanDerWaalsContact OH-CD 3.32Å; Y25-E398 PolarHBondContact OH-OE2 3.47Å; Y25-T401 PolarHBondContact OH-OG1 2.69Å
26W96.3Very high92.1Very high0 Ų063.9 Ų63.90%033%0.33CS..THydrogen-bonded Turntrans-74.8-35.7-177.8-66.8121.7000113N24 R28 R29 G30 V31 H33 F70 G72 F73 Y74 P79 A80 A81 T401N24-W26 PolarHBondContact O-N 3.42Å; W26-R28 VanDerWaalsContact C-N 3.34Å; W26-R28 PolarHBondContact O-N 2.79Å; W26-R29 CarbonylContact O-C 3.58Å; W26-R29 PolarHBondContact O-N 2.82Å; W26-G30 PolarHBondContact O-N 3.31Å; W26-V31 HydrophobicContact CB-CB 4.45Å; W26-V31 HydrophobicContact CD2-CB 4.48Å; W26-V31 HydrophobicContact CE3-CB 3.69Å; W26-V31 HydrophobicContact CE3-CG1 3.88Å; W26-V31 HydrophobicContact CE3-CG2 3.79Å; W26-V31 HydrophobicContact CZ3-CB 4.37Å; W26-V31 HydrophobicContact CZ3-CG1 4.32Å; W26-V31 HydrophobicContact CZ3-CG2 4.09Å; W26-V31 PolarHBondContact O-N 3.1Å; W26-H33 HydrophobicContact CB-CB 4.15Å; W26-H33 WeakPolarHBondContact CB-ND1 3.3Å; W26-H33 HydrophobicContact CG-CB 4.5Å; W26-F70 HydrophobicContact CE3-CE2 4.47Å; W26-F70 AromaticContact CH2-CE2 3.98Å; W26-F70 HydrophobicContact CH2-CE2 3.98Å; W26-F70 AromaticContact CZ3-CE2 3.62Å; W26-F70 HydrophobicContact CZ3-CE2 3.62Å; W26-F70 HydrophobicContact CZ3-CZ 4.37Å; W26-G72 VanDerWaalsContact CD1-CA 3.44Å; W26-G72 VanDerWaalsContact CD2-CA 3.42Å; W26-G72 VanDerWaalsContact CE2-CA 3.44Å; W26-G72 VanDerWaalsContact CG-CA 3.49Å; W26-F73 PolarHBondContact NE1-O 3.24Å; W26-F73 VanDerWaalsContact NE1-O 3.16Å; W26-Y74 AromaticContact CD1-CE2 3.44Å; W26-Y74 VanDerWaalsContact CD1-CE2 3.44Å; W26-Y74 AromaticContact CD1-CZ 3.65Å; W26-Y74 HydrophobicContact CG-CE2 4.47Å; W26-P79 HydrophobicContact CZ2-CB 4.33Å; W26-A80 WeakPolarHBondContact CZ2-O 3.31Å; W26-A81 HydrophobicContact CH2-CB 4.02Å; W26-A81 HydrophobicContact CZ2-CB 4.44Å; W26-T401 HydrophobicContact CH2-CG2 4.03Å; W26-T401 HydrophobicContact CZ2-CG2 4.15Å
27N94.7Very high92.3Very high103 Ų10364.8 Ų64.855%0.55132%0.324SS*.G310 helixtrans-58.2-45.2175.7-17035.2000111.9R29 G30 H33N27-R29 PolarHBondContact O-N 2.94Å; N27-R29 VanDerWaalsContact O-N 3.11Å; N27-G30 PolarHBondContact O-N 2.8Å; N27-G30 VanDerWaalsContact O-N 3.12Å; N27-H33 PolarHBondContact N-CE1 2.84Å
28R93.6Very high92Very high126 Ų12662 Ų6248%0.47532%0.322SS..G310 helixtrans-63.2-17.2176.5-71.8-166.8-56.8-90.2-4.7114.3R21 N24 W26R21-R28 VanDerWaalsContact O-CZ 3.22Å; R21-R28 PolarHBondContact O-NH1 3.1Å; R21-R28 PolarHBondContact O-NH2 3.15Å; N24-R28 WeakPolarHBondContact O-CG 3.48Å; N24-R28 PolarHBondContact O-N 2.76Å; N24-R28 VanDerWaalsContact O-N 3.14Å; W26-R28 VanDerWaalsContact C-N 3.34Å; W26-R28 PolarHBondContact O-N 2.79Å
29R94.2Very high91.8Very high74 Ų7464 Ų6428%0.27933%0.333SS..G310 helixtrans-102.4-0.3-179.5-72.7165.3-179.571.24.6112.8Y25 W26 N27 V31 E398Y25-R29 VanDerWaalsContact CZ-CZ 3.4Å; Y25-R29 VanDerWaalsContact CZ-NE 3.26Å; Y25-R29 PolarHBondContact O-NH1 3.04Å; Y25-R29 PolarHBondContact OH-NE 3.44Å; W26-R29 CarbonylContact O-C 3.58Å; W26-R29 PolarHBondContact O-N 2.82Å; N27-R29 PolarHBondContact O-N 2.94Å; N27-R29 VanDerWaalsContact O-N 3.11Å; R29-V31 HydrophobicContact CB-CG2 3.96Å; R29-V31 PolarHBondContact O-N 3.37Å; R29-E398 IonicContact CZ-OE1 3.94Å; R29-E398 IonicContact CZ-OE2 2.64Å; R29-E398 VanDerWaalsContact CZ-OE2 3.25Å; R29-E398 IonicContact NE-OE1 2.73Å; R29-E398 PolarHBondContact NE-OE1 3.44Å; R29-E398 IonicContact NE-OE2 2.76Å; R29-E398 PolarHBondContact NE-OE2 3.41Å; R29-E398 IonicContact NH2-OE1 3.22Å; R29-E398 PolarHBondContact NH2-OE1 2.83Å; R29-E398 IonicContact NH2-OE2 2.67Å; R29-E398 PolarHBondContact NH2-OE2 3.31Å
30G93.8Very high91.8Very high55 Ų5562.4 Ų62.457%0.56733%0.326SS*.THydrogen-bonded Turntrans62.425.1-17600000113.4W26 N27W26-G30 PolarHBondContact O-N 3.31Å; N27-G30 PolarHBondContact O-N 2.8Å; N27-G30 VanDerWaalsContact O-N 3.12Å
31V96.8Very high92Very high6 Ų656.8 Ų56.84%0.03630%0.301CS..  trans-91.6127.7177.3-179.80000108.8W26 R29 H33 F70 G72 L395W26-V31 HydrophobicContact CB-CB 4.45Å; W26-V31 HydrophobicContact CD2-CB 4.48Å; W26-V31 HydrophobicContact CE3-CB 3.69Å; W26-V31 HydrophobicContact CE3-CG1 3.88Å; W26-V31 HydrophobicContact CE3-CG2 3.79Å; W26-V31 HydrophobicContact CZ3-CB 4.37Å; W26-V31 HydrophobicContact CZ3-CG1 4.32Å; W26-V31 HydrophobicContact CZ3-CG2 4.09Å; W26-V31 PolarHBondContact O-N 3.1Å; R29-V31 HydrophobicContact CB-CG2 3.96Å; R29-V31 PolarHBondContact O-N 3.37Å; V31-H33 PolarHBondContact O-N 2.71Å; V31-H33 PolarHBondContact O-ND1 3.2Å; V31-F70 HydrophobicContact CG1-CD2 4.2Å; V31-F70 HydrophobicContact CG1-CE2 3.8Å; V31-F70 HydrophobicContact CG2-CE2 4.12Å; V31-F70 HydrophobicContact CG2-CZ 4.28Å; V31-G72 VanDerWaalsContact CG1-N 3.32Å; V31-L395 HydrophobicContact CG2-CD2 4.3Å
32P96.7Very high92.3Very high34 Ų3451.7 Ų51.722%0.22128%0.283CS..  trans-57137.2175.5-23.132.6000111.4Y63 F68 V71 G72P32-Y63 HydrophobicContact CB-CD1 4.37Å; P32-Y63 HydrophobicContact CB-CE1 3.99Å; P32-F68 HydrophobicContact CG-CD1 4Å; P32-F68 HydrophobicContact CG-CD2 3.62Å; P32-F68 HydrophobicContact CG-CE1 3.9Å; P32-F68 HydrophobicContact CG-CE2 3.51Å; P32-F68 HydrophobicContact CG-CG 3.87Å; P32-F68 HydrophobicContact CG-CZ 3.65Å; P32-V71 HydrophobicContact CB-CG1 4.15Å; P32-V71 WeakPolarHBondContact O-CB 3.46Å; P32-G72 PolarHBondContact O-N 3.48Å
33H96.1Very high92.4Very high41 Ų4149.5 Ų49.519%0.1927%0.272CS..BIsolated β-bridgetrans-164.5160.4178.561.5-69.9000110.1W26 N27 V31 Y63 G72W26-H33 HydrophobicContact CB-CB 4.15Å; W26-H33 WeakPolarHBondContact CB-ND1 3.3Å; W26-H33 HydrophobicContact CG-CB 4.5Å; N27-H33 PolarHBondContact N-CE1 2.84Å; V31-H33 PolarHBondContact O-N 2.71Å; V31-H33 PolarHBondContact O-ND1 3.2Å; H33-Y63 PolarHBondContact O-OH 3.26Å; H33-G72 WeakPolarHBondContact CB-O 3.3Å
34D95.1Very high92.5Very high47 Ų4752.4 Ų52.425%0.25129%0.29SS..PPolyproline II helixtrans-84.1145.1167.4-79.8-23.5000111.6P36 N42 Y59 K62 Y63D34-P36 VanDerWaalsContact O-CD 3.24Å; D34-P36 WeakPolarHBondContact O-CD 3.47Å; D34-P36 VanDerWaalsContact O-N 3.13Å; D34-N42 WeakPolarHBondContact CB-ND2 3.49Å; D34-N42 PolarHBondContact O-ND2 3.25Å; D34-N42 VanDerWaalsContact O-ND2 3.15Å; D34-Y59 HydrophobicContact CB-CE2 3.92Å; D34-Y59 PolarHBondContact N-OH 3.32Å; D34-K62 WeakPolarHBondContact OD1-CE 3.44Å; D34-K62 IonicContact OD1-NZ 3.94Å; D34-K62 PolarHBondContact OD1-NZ 2.92Å; D34-K62 IonicContact OD2-NZ 2.64Å; D34-K62 PolarHBondContact OD2-NZ 2.97Å; D34-Y63 PolarHBondContact N-OH 3.33Å; D34-Y63 PolarHBondContact OD1-OH 2.96Å; D34-Y63 VanDerWaalsContact OD1-OH 3.04Å
35A92.4Very high92.1Very high90 Ų9050.6 Ų50.674%0.74428%0.282SS*.PPolyproline II helixtrans-56.1117.5172.300000109.8
36P92.3Very high91.7Very high19 Ų1950.7 Ų50.712%0.12328%0.283CS..PPolyproline II helixtrans-71.5135.6-176.324.9-33.6000112.6F23 D34 Y74F23-P36 HydrophobicContact CB-CG 4.05Å; F23-P36 HydrophobicContact CD1-CB 3.75Å; F23-P36 HydrophobicContact CD1-CG 3.3Å; F23-P36 HydrophobicContact CE1-CB 3.68Å; F23-P36 HydrophobicContact CE1-CG 3.81Å; F23-P36 HydrophobicContact CG-CG 3.87Å; D34-P36 VanDerWaalsContact O-CD 3.24Å; D34-P36 WeakPolarHBondContact O-CD 3.47Å; D34-P36 VanDerWaalsContact O-N 3.13Å; P36-Y74 HydrophobicContact CB-CD1 4.34Å; P36-Y74 HydrophobicContact CB-CD2 3.54Å; P36-Y74 HydrophobicContact CB-CE2 4.15Å; P36-Y74 HydrophobicContact CB-CG 3.64Å; P36-Y74 HydrophobicContact CG-CD1 4.41Å; P36-Y74 HydrophobicContact CG-CD2 3.57Å; P36-Y74 HydrophobicContact CG-CE1 4.49Å; P36-Y74 HydrophobicContact CG-CE2 3.63Å; P36-Y74 HydrophobicContact CG-CG 3.97Å
37H91.2Very high91Very high76 Ų7651.9 Ų51.935%0.35229%0.288SS..BIsolated β-bridgetrans-66.1139.9170-179-88.2000110.8L39 Y40 G41 V44H37-L39 VanDerWaalsContact C-N 3.29Å; H37-L39 PolarHBondContact ND1-N 3.04Å; H37-L39 PolarHBondContact O-N 2.98Å; H37-Y40 AromaticContact CE1-CD2 3.83Å; H37-Y40 AromaticContact ND1-CD2 3.65Å; H37-Y40 PolarHBondContact ND1-N 3.31Å; H37-Y40 PolarHBondContact O-N 3.27Å; H37-G41 VanDerWaalsContact CB-O 3.24Å; H37-G41 WeakPolarHBondContact CB-O 3.46Å; H37-G41 PolarHBondContact N-O 3.22Å; H37-G41 WeakPolarHBondContact O-CA 3.49Å; H37-G41 PolarHBondContact O-N 3.04Å; H37-V44 HydrophobicContact CB-CG2 3.51Å
38P84.4Confident90.6Very high73 Ų7354.3 Ų54.347%0.47429%0.293SS..THydrogen-bonded Turntrans-55.6-35-171.3-30.235.6000117.5Y19Y19-P38 WeakPolarHBondContact OH-CA 3.35Å; Y19-P38 WeakPolarHBondContact OH-CB 3.35Å
39L82.3Confident90.3Very high128 Ų12853.7 Ų53.767%0.6730%0.299SS*.THydrogen-bonded Turntrans-102.4-27.4-179.6-65175.6000114.1H37H37-L39 VanDerWaalsContact C-N 3.29Å; H37-L39 PolarHBondContact ND1-N 3.04Å; H37-L39 PolarHBondContact O-N 2.98Å
40Y87.2Confident90.2Very high59 Ų5953.6 Ų53.623%0.23130%0.299CS..THydrogen-bonded Turntrans-114.6-5.5-166.5-73.6-71.3000112.8H37 N42 M43 F46 L76H37-Y40 AromaticContact CE1-CD2 3.83Å; H37-Y40 AromaticContact ND1-CD2 3.65Å; H37-Y40 PolarHBondContact ND1-N 3.31Å; H37-Y40 PolarHBondContact O-N 3.27Å; Y40-N42 PolarHBondContact O-N 3.46Å; Y40-M43 WeakPolarHBondContact O-CB 3.43Å; Y40-M43 PolarHBondContact O-N 3.44Å; Y40-F46 HydrophobicContact CD1-CB 4.38Å; Y40-L76 HydrophobicContact CD1-CD2 4.48Å
41G91.8Very high90.1Very high1 Ų151.7 Ų51.71%0.0128%0.277CS..BIsolated β-bridgetrans57.7-127.9-170.500000110.3H37 M43 L76H37-G41 VanDerWaalsContact CB-O 3.24Å; H37-G41 WeakPolarHBondContact CB-O 3.46Å; H37-G41 PolarHBondContact N-O 3.22Å; H37-G41 WeakPolarHBondContact O-CA 3.49Å; H37-G41 PolarHBondContact O-N 3.04Å; G41-M43 VanDerWaalsContact C-N 3.32Å; G41-L76 WeakPolarHBondContact CA-O 3.41Å; G41-L76 PolarHBondContact N-O 3.48Å
42N94Very high89.9Confident25 Ų2552.2 Ų52.213%0.13428%0.279CS..THydrogen-bonded Turntrans-90.98.5175.6-57.3113.9000113.3D34 Y40 Y59 F73 Y74D34-N42 WeakPolarHBondContact CB-ND2 3.49Å; D34-N42 PolarHBondContact O-ND2 3.25Å; D34-N42 VanDerWaalsContact O-ND2 3.15Å; Y40-N42 PolarHBondContact O-N 3.46Å; N42-Y59 HydrophobicContact CB-CE2 4.12Å; N42-F73 HydrophobicContact CB-CD2 3.79Å; N42-F73 HydrophobicContact CB-CE2 3.57Å; N42-F73 HydrophobicContact CB-CZ 4.13Å; N42-Y74 PolarHBondContact N-O 3.3Å; N42-Y74 WeakPolarHBondContact OD1-CB 3.42Å; N42-Y74 PolarHBondContact OD1-N 3Å
43M91Very high89.8Confident1 Ų151.3 Ų51.31%0.00527%0.272CS..  trans-109.247.2-175.7-62.3167.733.400112.9Y40 G41 G45 F46 F55 F73 F75Y40-M43 WeakPolarHBondContact O-CB 3.43Å; Y40-M43 PolarHBondContact O-N 3.44Å; G41-M43 VanDerWaalsContact C-N 3.32Å; M43-G45 PolarHBondContact O-N 3.33Å; M43-G45 VanDerWaalsContact O-N 3.11Å; M43-F46 HydrophobicContact CB-CB 4.03Å; M43-F46 HydrophobicContact CE-CB 3.81Å; M43-F46 HydrophobicContact CE-CD1 3.66Å; M43-F46 HydrophobicContact CE-CD2 3.36Å; M43-F46 HydrophobicContact CE-CE1 3.98Å; M43-F46 HydrophobicContact CE-CE2 3.71Å; M43-F46 HydrophobicContact CE-CG 3.32Å; M43-F46 HydrophobicContact CE-CZ 3.99Å; M43-F46 VanDerWaalsContact O-CB 3.26Å; M43-F46 WeakPolarHBondContact O-CB 3.33Å; M43-F46 PolarHBondContact O-N 2.75Å; M43-F55 VanDerWaalsContact C-CE1 3.4Å; M43-F55 HydrophobicContact CB-CD1 4.37Å; M43-F55 HydrophobicContact CB-CD2 4.37Å; M43-F55 HydrophobicContact CB-CE1 4.4Å; M43-F55 HydrophobicContact CB-CE2 4.41Å; M43-F55 HydrophobicContact CB-CG 4.37Å; M43-F55 HydrophobicContact CB-CZ 4.41Å; M43-F55 HydrophobicContact CG-CG 4.34Å; M43-F73 HydrophobicContact CG-CE1 4.18Å; M43-F73 HydrophobicContact CG-CZ 3.63Å; M43-F73 HydrophobicContact SD-CE1 4.11Å; M43-F73 HydrophobicContact SD-CZ 4.11Å; M43-F75 HydrophobicContact CE-CD2 4.29Å; M43-F75 HydrophobicContact CE-CE1 4.24Å; M43-F75 HydrophobicContact CE-CE2 3.85Å; M43-F75 HydrophobicContact CE-CZ 3.82Å; M43-F75 HydrophobicContact SD-CB 4.42Å; M43-F75 HydrophobicContact SD-CD1 4.26Å; M43-F75 HydrophobicContact SD-CD2 3.34Å; M43-F75 WeakPolarHBondContact SD-CD2 3.36Å; M43-F75 HydrophobicContact SD-CE1 4.35Å; M43-F75 HydrophobicContact SD-CE2 3.47Å; M43-F75 WeakPolarHBondContact SD-CE2 3.3Å; M43-F75 HydrophobicContact SD-CG 3.77Å; M43-F75 HydrophobicContact SD-CZ 3.98Å
44V90.5Very high89.7Confident77 Ų7752.2 Ų52.247%0.46728%0.278SS..THydrogen-bonded Turntrans-62.8113.1-178.4179.20000110.7H37 F55H37-V44 HydrophobicContact CB-CG2 3.51Å; V44-F55 WeakPolarHBondContact O-CE1 3.47Å; V44-F55 WeakPolarHBondContact O-CZ 3.44Å
45G85.5Confident89.7Confident6 Ų650.3 Ų50.36%0.06227%0.267CS..THydrogen-bonded Turntrans106.60.6-175.400000114.6M43 R47 K48 N49 R50M43-G45 PolarHBondContact O-N 3.33Å; M43-G45 VanDerWaalsContact O-N 3.11Å; G45-R47 PolarHBondContact O-N 3.08Å; G45-K48 WeakPolarHBondContact O-CB 3.42Å; G45-K48 PolarHBondContact O-N 3.43Å; G45-N49 WeakPolarHBondContact CA-OD1 3.49Å; G45-N49 PolarHBondContact O-N 2.89Å; G45-N49 PolarHBondContact O-OD1 3.15Å; G45-R50 PolarHBondContact O-N 2.89Å
46F86.2Confident89.9Confident23 Ų2346 Ų4610%0.10123%0.232CC..BIsolated β-bridgetrans-56129.4175.8-180-116.2000111.8Y40 M43 K48 M52 F55 L76Y40-F46 HydrophobicContact CD1-CB 4.38Å; M43-F46 HydrophobicContact CB-CB 4.03Å; M43-F46 HydrophobicContact CE-CB 3.81Å; M43-F46 HydrophobicContact CE-CD1 3.66Å; M43-F46 HydrophobicContact CE-CD2 3.36Å; M43-F46 HydrophobicContact CE-CE1 3.98Å; M43-F46 HydrophobicContact CE-CE2 3.71Å; M43-F46 HydrophobicContact CE-CG 3.32Å; M43-F46 HydrophobicContact CE-CZ 3.99Å; M43-F46 VanDerWaalsContact O-CB 3.26Å; M43-F46 WeakPolarHBondContact O-CB 3.33Å; M43-F46 PolarHBondContact O-N 2.75Å; F46-K48 PolarHBondContact O-N 2.66Å; F46-M52 HydrophobicContact CD2-CG 4.34Å; F46-M52 HydrophobicContact CE2-CG 3.89Å; F46-M52 HydrophobicContact CE2-SD 4.18Å; F46-F55 HydrophobicContact CB-CE2 4.09Å; F46-F55 HydrophobicContact CB-CZ 4.37Å; F46-F55 HydrophobicContact CD2-CE2 4.45Å; F46-L76 HydrophobicContact CD1-CD2 4.39Å
47R81.8Confident90.1Very high26 Ų2648.3 Ų48.310%0.09824%0.239CC..THydrogen-bonded Turntrans53.830.5-175.3-61.1-165.9-179.2-125.520.6114.2G45 K221 P488 M489 I491G45-R47 PolarHBondContact O-N 3.08Å; R47-K221 PolarHBondContact O-NZ 3.46Å; R47-P488 VanDerWaalsContact CA-O 3.24Å; R47-P488 WeakPolarHBondContact CA-O 3.36Å; R47-M489 HydrophobicContact CB-SD 3.91Å; R47-M489 PolarHBondContact NH1-O 2.88Å; R47-M489 VanDerWaalsContact O-SD 3.41Å; R47-I491 VanDerWaalsContact NH2-CG1 3.33Å
48K85.3Confident90.4Very high153 Ų15348.7 Ų48.767%0.66524%0.243SC*.THydrogen-bonded Turntrans-128.2-63.6172.7-172.1179.1179.1-1780111.2G45 F46G45-K48 WeakPolarHBondContact O-CB 3.42Å; G45-K48 PolarHBondContact O-N 3.43Å; F46-K48 PolarHBondContact O-N 2.66Å
49N88Confident91Very high113 Ų11345.8 Ų45.860%0.60422%0.223SC*.THydrogen-bonded Turntrans-146.2-0.1-171.463.9-21.1000114.8G45G45-N49 WeakPolarHBondContact CA-OD1 3.49Å; G45-N49 PolarHBondContact O-N 2.89Å; G45-N49 PolarHBondContact O-OD1 3.15Å
50R91.3Very high91.8Very high72 Ų7240 Ų4027%0.27219%0.192SC..BIsolated β-bridgetrans-131.3147178.1-67.2-176.165.9177.23.7111G45 D54 F55 D58 P488G45-R50 PolarHBondContact O-N 2.89Å; R50-D54 VanDerWaalsContact NH2-C 3.34Å; R50-D54 VanDerWaalsContact NH2-CB 3.34Å; R50-D54 PolarHBondContact NH2-O 3.42Å; R50-F55 HydrophobicContact CB-CE1 4.19Å; R50-F55 HydrophobicContact CB-CE2 3.7Å; R50-F55 HydrophobicContact CB-CZ 3.47Å; R50-F55 VanDerWaalsContact CB-CZ 3.47Å; R50-F55 HydrophobicContact CG-CZ 4.26Å; R50-D58 IonicContact CZ-OD2 3.39Å; R50-D58 IonicContact NH1-OD2 3.18Å; R50-D58 IonicContact NH2-OD2 3.89Å; R50-D58 PolarHBondContact NH2-OD2 3.41Å; R50-P488 WeakPolarHBondContact O-CB 3.45Å
51V92.6Very high92.2Very high16 Ų1639.6 Ų39.610%0.09719%0.194CC..  trans-91.5163.7174.3-66.90000111.1H53 D54 F55 S487V51-H53 HydrophobicContact CG2-CB 3.85Å; V51-H53 PolarHBondContact O-N 3.21Å; V51-D54 WeakPolarHBondContact CG2-OD1 3.48Å; V51-D54 WeakPolarHBondContact CG2-OD2 3.28Å; V51-D54 PolarHBondContact N-OD2 3.06Å; V51-D54 PolarHBondContact O-N 3Å; V51-F55 WeakPolarHBondContact O-CD2 3.38Å; V51-S487 WeakPolarHBondContact CG1-O 3.44Å
52M92.6Very high92.5Very high16 Ų1645.2 Ų45.28%0.07922%0.218CC..Hα-helixtrans-59-32.5177.1-78.7-165.8-69.200113.1F46 D54 F55 F56 P377 I491F46-M52 HydrophobicContact CD2-CG 4.34Å; F46-M52 HydrophobicContact CE2-CG 3.89Å; F46-M52 HydrophobicContact CE2-SD 4.18Å; M52-D54 PolarHBondContact O-N 3.44Å; M52-F55 PolarHBondContact O-N 2.82Å; M52-F56 HydrophobicContact CB-CD2 4.27Å; M52-F56 HydrophobicContact CB-CE2 3.83Å; M52-F56 HydrophobicContact CG-CE2 4.29Å; M52-F56 WeakPolarHBondContact O-CD2 3.48Å; M52-F56 WeakPolarHBondContact O-CG 3.49Å; M52-F56 PolarHBondContact O-N 2.87Å; M52-F56 VanDerWaalsContact O-N 3.14Å; M52-F56 HydrophobicContact SD-CE2 4.28Å; M52-P377 HydrophobicContact CB-CB 4.42Å; M52-P377 HydrophobicContact CB-CG 3.6Å; M52-P377 HydrophobicContact CE-CG 4.1Å; M52-I491 HydrophobicContact CE-CG2 3.99Å; M52-I491 WeakPolarHBondContact CE-O 3.28Å
53H94.6Very high92.7Very high16 Ų1645.1 Ų45.17%0.07422%0.216CC..Hα-helixtrans-54.2-50.6174.9-124.1-87.7000111.5V51 F55 F56 Y57 T374 C408 L493V51-H53 HydrophobicContact CG2-CB 3.85Å; V51-H53 PolarHBondContact O-N 3.21Å; H53-F55 VanDerWaalsContact C-N 3.33Å; H53-F55 PolarHBondContact O-N 2.83Å; H53-F56 PolarHBondContact O-N 3.06Å; H53-Y57 WeakPolarHBondContact O-CB 3.38Å; H53-Y57 PolarHBondContact O-N 2.87Å; H53-T374 PolarHBondContact NE2-O 3.48Å; H53-C408 WeakPolarHBondContact CE1-CB 3.34Å; H53-C408 WeakPolarHBondContact ND1-CB 2.88Å; H53-C408 VanDerWaalsContact NE2-CB 3.26Å; H53-C408 WeakPolarHBondContact NE2-CB 3.04Å; H53-L493 HydrophobicContact CB-CD1 4.47Å
54D94.6Very high92.9Very high60 Ų6046.9 Ų46.932%0.32122%0.223SC..Hα-helixtrans-60.2-43.5-178-45-29000111.4R50 V51 M52 D58R50-D54 VanDerWaalsContact NH2-C 3.34Å; R50-D54 VanDerWaalsContact NH2-CB 3.34Å; R50-D54 PolarHBondContact NH2-O 3.42Å; V51-D54 WeakPolarHBondContact CG2-OD1 3.48Å; V51-D54 WeakPolarHBondContact CG2-OD2 3.28Å; V51-D54 PolarHBondContact N-OD2 3.06Å; V51-D54 PolarHBondContact O-N 3Å; M52-D54 PolarHBondContact O-N 3.44Å; D54-D58 WeakPolarHBondContact O-CB 3.3Å; D54-D58 PolarHBondContact O-N 2.91Å
55F95.1Very high93.1Very high7 Ų750.4 Ų50.43%0.03123%0.232CC..Hα-helixtrans-63.6-48-178.6-67.3-60.4000111.9M43 V44 F46 R50 V51 M52 H53 Y59M43-F55 VanDerWaalsContact C-CE1 3.4Å; M43-F55 HydrophobicContact CB-CD1 4.37Å; M43-F55 HydrophobicContact CB-CD2 4.37Å; M43-F55 HydrophobicContact CB-CE1 4.4Å; M43-F55 HydrophobicContact CB-CE2 4.41Å; M43-F55 HydrophobicContact CB-CG 4.37Å; M43-F55 HydrophobicContact CB-CZ 4.41Å; M43-F55 HydrophobicContact CG-CG 4.34Å; V44-F55 WeakPolarHBondContact O-CE1 3.47Å; V44-F55 WeakPolarHBondContact O-CZ 3.44Å; F46-F55 HydrophobicContact CB-CE2 4.09Å; F46-F55 HydrophobicContact CB-CZ 4.37Å; F46-F55 HydrophobicContact CD2-CE2 4.45Å; R50-F55 HydrophobicContact CB-CE1 4.19Å; R50-F55 HydrophobicContact CB-CE2 3.7Å; R50-F55 HydrophobicContact CB-CZ 3.47Å; R50-F55 VanDerWaalsContact CB-CZ 3.47Å; R50-F55 HydrophobicContact CG-CZ 4.26Å; V51-F55 WeakPolarHBondContact O-CD2 3.38Å; M52-F55 PolarHBondContact O-N 2.82Å; H53-F55 VanDerWaalsContact C-N 3.33Å; H53-F55 PolarHBondContact O-N 2.83Å; F55-Y59 WeakPolarHBondContact O-CB 3.4Å; F55-Y59 PolarHBondContact O-N 2.98Å; F55-Y59 VanDerWaalsContact O-N 3.15Å
56F96.6Very high93.5Very high0 Ų052.2 Ų52.20%024%0.243CC..Hα-helixtrans-75.1-36.1-176.3-59.5-39.3000112.1M52 H53 Y60 F73 F75 F82 P377 H378 I404 P406M52-F56 HydrophobicContact CB-CD2 4.27Å; M52-F56 HydrophobicContact CB-CE2 3.83Å; M52-F56 HydrophobicContact CG-CE2 4.29Å; M52-F56 WeakPolarHBondContact O-CD2 3.48Å; M52-F56 WeakPolarHBondContact O-CG 3.49Å; M52-F56 PolarHBondContact O-N 2.87Å; M52-F56 VanDerWaalsContact O-N 3.14Å; M52-F56 HydrophobicContact SD-CE2 4.28Å; H53-F56 PolarHBondContact O-N 3.06Å; F56-Y60 WeakPolarHBondContact O-CB 3.2Å; F56-Y60 PolarHBondContact O-N 3.46Å; F56-F73 HydrophobicContact CD1-CZ 4.34Å; F56-F73 HydrophobicContact CE1-CE1 4.24Å; F56-F73 AromaticContact CE1-CZ 3.92Å; F56-F73 HydrophobicContact CE1-CZ 3.92Å; F56-F75 HydrophobicContact CZ-CE2 4.47Å; F56-F82 HydrophobicContact CB-CE2 4.2Å; F56-F82 HydrophobicContact CB-CZ 4.29Å; F56-F82 HydrophobicContact CD1-CD2 4.46Å; F56-F82 AromaticContact CD1-CE2 3.63Å; F56-F82 HydrophobicContact CD1-CE2 3.63Å; F56-F82 HydrophobicContact CD1-CZ 4.49Å; F56-F82 HydrophobicContact CE1-CE2 4.4Å; F56-F82 HydrophobicContact CG-CE2 4.23Å; F56-P377 HydrophobicContact CD2-CB 4.22Å; F56-P377 HydrophobicContact CD2-CG 4.48Å; F56-P377 HydrophobicContact CE2-CG 4.35Å; F56-H378 HydrophobicContact CD2-CB 3.88Å; F56-H378 HydrophobicContact CE2-CB 3.62Å; F56-H378 AromaticContact CE2-CE1 3.83Å; F56-H378 AromaticContact CE2-CG 3.35Å; F56-H378 AromaticContact CE2-ND1 3.18Å; F56-H378 WeakPolarHBondContact CE2-ND1 3.49Å; F56-H378 HydrophobicContact CZ-CB 4.13Å; F56-H378 AromaticContact CZ-CD2 3.92Å; F56-H378 AromaticContact CZ-CE1 3.96Å; F56-H378 AromaticContact CZ-CG 3.64Å; F56-H378 AromaticContact CZ-ND1 3.7Å; F56-I404 HydrophobicContact CD1-CG2 4.46Å; F56-I404 HydrophobicContact CE1-CG2 4.11Å; F56-I404 HydrophobicContact CZ-CG2 4.45Å; F56-P406 HydrophobicContact CB-CB 4.01Å
57Y96.4Very high93.9Very high67 Ų6754.2 Ų54.226%0.26327%0.271SS..Hα-helixtrans-63.8-51176.1-176.9-106.1000111.9H53 Y59 Y60 N61 A409 R412H53-Y57 WeakPolarHBondContact O-CB 3.38Å; H53-Y57 PolarHBondContact O-N 2.87Å; Y57-Y59 PolarHBondContact O-N 3.34Å; Y57-Y60 PolarHBondContact O-N 3.37Å; Y57-N61 WeakPolarHBondContact CE1-ND2 3.41Å; Y57-N61 VanDerWaalsContact CE2-ND2 3.25Å; Y57-N61 WeakPolarHBondContact CE2-ND2 3.46Å; Y57-N61 WeakPolarHBondContact O-CB 3.24Å; Y57-N61 PolarHBondContact O-N 3.19Å; Y57-N61 PolarHBondContact O-ND2 2.94Å; Y57-N61 PolarHBondContact OH-ND2 3.42Å; Y57-A409 HydrophobicContact CD2-CB 4.47Å; Y57-R412 HydrophobicContact CD2-CB 4Å; Y57-R412 HydrophobicContact CE2-CB 3.51Å
58D96.6Very high94.6Very high84 Ų8456.4 Ų56.445%0.44928%0.281SS..Hα-helixtrans-62.1-44.3179.4-69.2-6.4000111.6R50 D54 N61 K62R50-D58 IonicContact CZ-OD2 3.39Å; R50-D58 IonicContact NH1-OD2 3.18Å; R50-D58 IonicContact NH2-OD2 3.89Å; R50-D58 PolarHBondContact NH2-OD2 3.41Å; D54-D58 WeakPolarHBondContact O-CB 3.3Å; D54-D58 PolarHBondContact O-N 2.91Å; D58-N61 PolarHBondContact O-N 3.22Å; D58-K62 WeakPolarHBondContact O-CB 3.27Å; D58-K62 PolarHBondContact O-N 3.3Å; D58-K62 VanDerWaalsContact O-N 3.1Å
59Y97.4Very high95.1Very high12 Ų1249.3 Ų49.35%0.04725%0.25CS..Hα-helixtrans-65.4-42.5-179.8-151.6-98.8000111.3D34 N42 F55 Y57 K62 Y63 V71 G72 F73 F82D34-Y59 HydrophobicContact CB-CE2 3.92Å; D34-Y59 PolarHBondContact N-OH 3.32Å; N42-Y59 HydrophobicContact CB-CE2 4.12Å; F55-Y59 WeakPolarHBondContact O-CB 3.4Å; F55-Y59 PolarHBondContact O-N 2.98Å; F55-Y59 VanDerWaalsContact O-N 3.15Å; Y57-Y59 PolarHBondContact O-N 3.34Å; Y59-K62 PolarHBondContact O-N 2.96Å; Y59-Y63 AromaticContact CD1-CD2 3.93Å; Y59-Y63 HydrophobicContact CD1-CD2 3.93Å; Y59-Y63 HydrophobicContact CD1-CE2 4.19Å; Y59-Y63 HydrophobicContact CD2-CE2 4.34Å; Y59-Y63 AromaticContact CE1-CD2 3.8Å; Y59-Y63 HydrophobicContact CE1-CD2 3.8Å; Y59-Y63 AromaticContact CE1-CE2 3.74Å; Y59-Y63 HydrophobicContact CE1-CE2 3.74Å; Y59-Y63 AromaticContact CE2-CE2 3.9Å; Y59-Y63 HydrophobicContact CE2-CE2 3.9Å; Y59-Y63 HydrophobicContact CG-CD2 4.38Å; Y59-Y63 HydrophobicContact CG-CE2 4.48Å; Y59-Y63 AromaticContact CZ-CE2 3.57Å; Y59-Y63 VanDerWaalsContact O-CD2 3.31Å; Y59-Y63 WeakPolarHBondContact O-CD2 3.47Å; Y59-Y63 PolarHBondContact O-N 3.37Å; Y59-V71 HydrophobicContact CD1-CG2 4.2Å; Y59-V71 HydrophobicContact CE1-CG2 3.7Å; Y59-G72 PolarHBondContact OH-O 3.49Å; Y59-F73 AromaticContact CD1-CD2 3.78Å; Y59-F73 HydrophobicContact CD1-CD2 3.78Å; Y59-F73 HydrophobicContact CD1-CE2 4.41Å; Y59-F73 HydrophobicContact CD2-CD2 4.16Å; Y59-F73 HydrophobicContact CD2-CE2 4.3Å; Y59-F73 HydrophobicContact CE1-CB 4.22Å; Y59-F73 AromaticContact CE1-CD2 3.72Å; Y59-F73 HydrophobicContact CE1-CD2 3.72Å; Y59-F73 HydrophobicContact CE1-CG 4.48Å; Y59-F73 HydrophobicContact CE2-CD2 4.12Å; Y59-F73 HydrophobicContact CG-CD2 4Å; Y59-F73 HydrophobicContact CG-CE2 4.21Å; Y59-F73 AromaticContact CZ-CD2 3.9Å; Y59-F82 AromaticContact CD1-CD1 3.91Å; Y59-F82 HydrophobicContact CD1-CD1 3.91Å; Y59-F82 HydrophobicContact CD1-CD2 4.4Å; Y59-F82 HydrophobicContact CD1-CE1 4.09Å; Y59-F82 HydrophobicContact CD1-CG 4.06Å; Y59-F82 HydrophobicContact CD1-CZ 4.41Å; Y59-F82 HydrophobicContact CE1-CG 4.47Å
60Y97.9Very high95.6Very high7 Ų743.9 Ų43.93%0.02722%0.221CC..Hα-helixtrans-61.1-52.1175.7179-104.4000111.8F56 Y57 K62 Y63 R64 F82 V84 P406 A409 Y410 D413F56-Y60 WeakPolarHBondContact O-CB 3.2Å; F56-Y60 PolarHBondContact O-N 3.46Å; Y57-Y60 PolarHBondContact O-N 3.37Å; Y60-K62 PolarHBondContact O-N 3.45Å; Y60-Y63 CarbonylContact O-C 3.53Å; Y60-Y63 PolarHBondContact O-N 3.45Å; Y60-R64 HydrophobicContact CD1-CB 4.25Å; Y60-R64 HydrophobicContact CD2-CB 4.37Å; Y60-R64 HydrophobicContact CE1-CB 3.89Å; Y60-R64 VanDerWaalsContact CE1-CD 3.42Å; Y60-R64 HydrophobicContact CE1-CG 4.23Å; Y60-R64 HydrophobicContact CE2-CB 3.97Å; Y60-R64 HydrophobicContact CG-CB 4.49Å; Y60-R64 WeakPolarHBondContact O-CB 3.28Å; Y60-R64 PolarHBondContact O-N 2.85Å; Y60-F82 HydrophobicContact CD2-CE1 4.29Å; Y60-V84 HydrophobicContact CD2-CG1 4.36Å; Y60-V84 HydrophobicContact CE2-CG1 4.02Å; Y60-V84 WeakPolarHBondContact CE2-O 3.42Å; Y60-P406 HydrophobicContact CD2-CG 3.98Å; Y60-A409 VanDerWaalsContact CB-CB 3.47Å; Y60-A409 HydrophobicContact CD1-CB 3.59Å; Y60-A409 HydrophobicContact CD2-CB 4.31Å; Y60-A409 HydrophobicContact CE1-CB 4.4Å; Y60-A409 HydrophobicContact CG-CB 3.52Å; Y60-Y410 HydrophobicContact CD2-CD1 4.33Å; Y60-Y410 HydrophobicContact CD2-CE1 4.08Å; Y60-Y410 AromaticContact CE2-CD1 3.74Å; Y60-Y410 HydrophobicContact CE2-CD1 3.74Å; Y60-Y410 AromaticContact CE2-CE1 3.49Å; Y60-Y410 HydrophobicContact CE2-CE1 3.49Å; Y60-Y410 VanDerWaalsContact CE2-CE1 3.49Å; Y60-Y410 AromaticContact CZ-CD1 3.85Å; Y60-D413 HydrophobicContact CE1-CB 4.04Å; Y60-D413 PolarHBondContact OH-OD2 3.32Å
61N97.1Very high96Very high50 Ų5040.5 Ų40.527%0.26721%0.209SC..Hα-helixtrans-61.3-33.2-178.1-80.4-32.6000113.2Y57 D58 Y63 R64Y57-N61 WeakPolarHBondContact CE1-ND2 3.41Å; Y57-N61 VanDerWaalsContact CE2-ND2 3.25Å; Y57-N61 WeakPolarHBondContact CE2-ND2 3.46Å; Y57-N61 WeakPolarHBondContact O-CB 3.24Å; Y57-N61 PolarHBondContact O-N 3.19Å; Y57-N61 PolarHBondContact O-ND2 2.94Å; Y57-N61 PolarHBondContact OH-ND2 3.42Å; D58-N61 PolarHBondContact O-N 3.22Å; N61-Y63 VanDerWaalsContact C-N 3.32Å; N61-Y63 PolarHBondContact O-N 3.09Å; N61-R64 PolarHBondContact OD1-NH1 2.77Å; N61-R64 VanDerWaalsContact OD1-NH1 3.14Å
62K97.3Very high96.2Very high118 Ų11839.7 Ų39.751%0.51320%0.204SC..Hα-helixtrans-64-35.9174.3-179.2172.7175.2174.10113.1D34 D58 Y59 Y60D34-K62 WeakPolarHBondContact OD1-CE 3.44Å; D34-K62 IonicContact OD1-NZ 3.94Å; D34-K62 PolarHBondContact OD1-NZ 2.92Å; D34-K62 IonicContact OD2-NZ 2.64Å; D34-K62 PolarHBondContact OD2-NZ 2.97Å; D58-K62 WeakPolarHBondContact O-CB 3.27Å; D58-K62 PolarHBondContact O-N 3.3Å; D58-K62 VanDerWaalsContact O-N 3.1Å; Y59-K62 PolarHBondContact O-N 2.96Å; Y60-K62 PolarHBondContact O-N 3.45Å
63Y97.6Very high96.4Very high23 Ų2339 Ų399%0.0920%0.2CC..Hα-helixtrans-111-9.7-171.3-70.5-70.4000115P32 H33 D34 Y59 Y60 N61 K65 S66 V71P32-Y63 HydrophobicContact CB-CD1 4.37Å; P32-Y63 HydrophobicContact CB-CE1 3.99Å; H33-Y63 PolarHBondContact O-OH 3.26Å; D34-Y63 PolarHBondContact N-OH 3.33Å; D34-Y63 PolarHBondContact OD1-OH 2.96Å; D34-Y63 VanDerWaalsContact OD1-OH 3.04Å; Y59-Y63 AromaticContact CD1-CD2 3.93Å; Y59-Y63 HydrophobicContact CD1-CD2 3.93Å; Y59-Y63 HydrophobicContact CD1-CE2 4.19Å; Y59-Y63 HydrophobicContact CD2-CE2 4.34Å; Y59-Y63 AromaticContact CE1-CD2 3.8Å; Y59-Y63 HydrophobicContact CE1-CD2 3.8Å; Y59-Y63 AromaticContact CE1-CE2 3.74Å; Y59-Y63 HydrophobicContact CE1-CE2 3.74Å; Y59-Y63 AromaticContact CE2-CE2 3.9Å; Y59-Y63 HydrophobicContact CE2-CE2 3.9Å; Y59-Y63 HydrophobicContact CG-CD2 4.38Å; Y59-Y63 HydrophobicContact CG-CE2 4.48Å; Y59-Y63 AromaticContact CZ-CE2 3.57Å; Y59-Y63 VanDerWaalsContact O-CD2 3.31Å; Y59-Y63 WeakPolarHBondContact O-CD2 3.47Å; Y59-Y63 PolarHBondContact O-N 3.37Å; Y60-Y63 CarbonylContact O-C 3.53Å; Y60-Y63 PolarHBondContact O-N 3.45Å; N61-Y63 VanDerWaalsContact C-N 3.32Å; N61-Y63 PolarHBondContact O-N 3.09Å; Y63-K65 PolarHBondContact O-N 2.91Å; Y63-K65 VanDerWaalsContact O-N 3.11Å; Y63-S66 WeakPolarHBondContact O-CB 3.36Å; Y63-S66 PolarHBondContact O-N 3.43Å; Y63-S66 PolarHBondContact O-OG 3.2Å; Y63-V71 HydrophobicContact CD1-CB 4.45Å; Y63-V71 HydrophobicContact CD1-CG1 3.78Å; Y63-V71 HydrophobicContact CD2-CG2 3.94Å; Y63-V71 HydrophobicContact CE1-CG1 4.48Å; Y63-V71 HydrophobicContact CG-CB 4.24Å; Y63-V71 HydrophobicContact CG-CG1 3.8Å; Y63-V71 HydrophobicContact CG-CG2 3.96Å
64R95.5Very high96.4Very high39 Ų3938.2 Ų38.215%0.14720%0.197CC..THydrogen-bonded Turntrans-59.4-27.5-175.771.6173.7-128.2-123.1-5.6115.3Y60 N61 V84 D413 E414 D415Y60-R64 HydrophobicContact CD1-CB 4.25Å; Y60-R64 HydrophobicContact CD2-CB 4.37Å; Y60-R64 HydrophobicContact CE1-CB 3.89Å; Y60-R64 VanDerWaalsContact CE1-CD 3.42Å; Y60-R64 HydrophobicContact CE1-CG 4.23Å; Y60-R64 HydrophobicContact CE2-CB 3.97Å; Y60-R64 HydrophobicContact CG-CB 4.49Å; Y60-R64 WeakPolarHBondContact O-CB 3.28Å; Y60-R64 PolarHBondContact O-N 2.85Å; N61-R64 PolarHBondContact OD1-NH1 2.77Å; N61-R64 VanDerWaalsContact OD1-NH1 3.14Å; R64-V84 HydrophobicContact CB-CG1 4Å; R64-D413 IonicContact CZ-OD1 3.79Å; R64-D413 IonicContact NE-OD1 3.64Å; R64-D413 PolarHBondContact NE-OD1 3.34Å; R64-D413 IonicContact NE-OD2 2.66Å; R64-D413 IonicContact NH1-OD1 2.71Å; R64-D413 PolarHBondContact NH1-OD1 2.9Å; R64-D413 IonicContact NH2-OD1 3.84Å; R64-D413 PolarHBondContact NH2-OD1 2.79Å; R64-E414 IonicContact CZ-OE1 3.48Å; R64-E414 IonicContact NH1-OE1 2.64Å; R64-E414 IonicContact NH2-OE1 3.22Å; R64-E414 PolarHBondContact NH2-OE1 2.58Å; R64-D415 IonicContact CZ-OD2 2.64Å; R64-D415 IonicContact NE-OD2 3.12Å; R64-D415 PolarHBondContact NE-OD2 3.06Å; R64-D415 VanDerWaalsContact NH2-CG 3.34Å; R64-D415 IonicContact NH2-OD1 3.51Å; R64-D415 IonicContact NH2-OD2 2.62Å; R64-D415 PolarHBondContact NH2-OD2 2.7Å
65K94.6Very high96.2Very high151 Ų15137 Ų3766%0.65719%0.189SC*.THydrogen-bonded Turntrans-100.415.3175.7-62.1179.9-178.4174.20113.4Y63 G67 E414Y63-K65 PolarHBondContact O-N 2.91Å; Y63-K65 VanDerWaalsContact O-N 3.11Å; K65-G67 VanDerWaalsContact C-N 3.33Å; K65-G67 PolarHBondContact O-N 3.46Å; K65-E414 IonicContact NZ-OE1 2.71Å
66S94.4Very high95.7Very high43 Ų4337 Ų3730%0.30119%0.189SC..SBendtrans-76.3-15.7-177.867.10000114.5Y63 F68Y63-S66 WeakPolarHBondContact O-CB 3.36Å; Y63-S66 PolarHBondContact O-N 3.43Å; Y63-S66 PolarHBondContact O-OG 3.2Å; S66-F68 WeakPolarHBondContact O-CD2 3.45Å; S66-F68 PolarHBondContact O-N 2.93Å; S66-F68 PolarHBondContact OG-N 2.87Å
67G93.6Very high95.1Very high66 Ų6638.7 Ų38.768%0.6820%0.197SC*.SBendtrans782.7-173.600000114.5K65K65-G67 VanDerWaalsContact C-N 3.33Å; K65-G67 PolarHBondContact O-N 3.46Å
68F96.8Very high94.7Very high72 Ų7238 Ų3832%0.31620%0.195SC..  trans-96137.1173.6-71.7-102.1000110.8P32 S66 F70 V71 L395P32-F68 HydrophobicContact CG-CD1 4Å; P32-F68 HydrophobicContact CG-CD2 3.62Å; P32-F68 HydrophobicContact CG-CE1 3.9Å; P32-F68 HydrophobicContact CG-CE2 3.51Å; P32-F68 HydrophobicContact CG-CG 3.87Å; P32-F68 HydrophobicContact CG-CZ 3.65Å; S66-F68 WeakPolarHBondContact O-CD2 3.45Å; S66-F68 PolarHBondContact O-N 2.93Å; S66-F68 PolarHBondContact OG-N 2.87Å; F68-F70 VanDerWaalsContact C-N 3.27Å; F68-F70 WeakPolarHBondContact CB-O 3.35Å; F68-F70 PolarHBondContact O-N 3.43Å; F68-V71 HydrophobicContact CB-CG1 4.37Å; F68-L395 HydrophobicContact CD1-CD1 3.91Å; F68-L395 HydrophobicContact CD1-CD2 4.26Å; F68-L395 HydrophobicContact CE1-CD2 4.29Å
69P97.3Very high94.6Very high3 Ų335.1 Ų35.12%0.01918%0.181CC..SBendtrans-71.6-24.4179.130.9-37.3000112.5V84 D85 L88 V389 L395P69-V84 PolarHBondContact O-N 2.7Å; P69-D85 HydrophobicContact CB-CB 3.99Å; P69-D85 PolarHBondContact O-N 3.23Å; P69-L88 HydrophobicContact CB-CB 4.35Å; P69-L88 HydrophobicContact CB-CD2 3.85Å; P69-L88 HydrophobicContact CG-CD2 4.43Å; P69-V389 HydrophobicContact CB-CG1 4.18Å; P69-V389 HydrophobicContact CG-CG1 3.74Å; P69-L395 HydrophobicContact CG-CD1 3.76Å
70F98.4Very high94.6Very high0 Ų034.6 Ų34.60%018%0.179CC..EExtended strand (participates in β ladder)trans-146.2157.9169.176.1-92.2000110.5W26 V31 F68 A81 F82 I83 L88 V389 L395 I397W26-F70 HydrophobicContact CE3-CE2 4.47Å; W26-F70 AromaticContact CH2-CE2 3.98Å; W26-F70 HydrophobicContact CH2-CE2 3.98Å; W26-F70 AromaticContact CZ3-CE2 3.62Å; W26-F70 HydrophobicContact CZ3-CE2 3.62Å; W26-F70 HydrophobicContact CZ3-CZ 4.37Å; V31-F70 HydrophobicContact CG1-CD2 4.2Å; V31-F70 HydrophobicContact CG1-CE2 3.8Å; V31-F70 HydrophobicContact CG2-CE2 4.12Å; V31-F70 HydrophobicContact CG2-CZ 4.28Å; F68-F70 VanDerWaalsContact C-N 3.27Å; F68-F70 WeakPolarHBondContact CB-O 3.35Å; F68-F70 PolarHBondContact O-N 3.43Å; F70-A81 HydrophobicContact CD2-CB 3.83Å; F70-A81 HydrophobicContact CE2-CB 4.21Å; F70-A81 HydrophobicContact CG-CB 4.35Å; F70-F82 CarbonylContact C-O 3.06Å; F70-F82 VanDerWaalsContact CA-O 3.25Å; F70-F82 WeakPolarHBondContact CA-O 3.32Å; F70-F82 WeakPolarHBondContact CB-O 3.37Å; F70-I83 HydrophobicContact CB-CD1 3.72Å; F70-L88 HydrophobicContact CB-CD2 4.12Å; F70-L88 HydrophobicContact CD1-CD2 4.01Å; F70-V389 HydrophobicContact CD1-CG2 3.92Å; F70-V389 HydrophobicContact CE1-CG2 3.64Å; F70-L395 HydrophobicContact CE1-CB 3.89Å; F70-L395 HydrophobicContact CZ-CB 4.36Å; F70-I397 HydrophobicContact CD1-CD1 4.35Å; F70-I397 HydrophobicContact CD1-CG1 4.2Å; F70-I397 HydrophobicContact CE1-CD1 4.44Å; F70-I397 HydrophobicContact CE1-CG1 3.82Å; F70-I397 HydrophobicContact CZ-CG1 4.06Å
71V98.4Very high94.6Very high0 Ų034.2 Ų34.20%018%0.177CC..EExtended strand (participates in β ladder)trans-123160.9173.7-66.90000110.6P32 Y59 Y63 F68 F82 V84P32-V71 HydrophobicContact CB-CG1 4.15Å; P32-V71 WeakPolarHBondContact O-CB 3.46Å; Y59-V71 HydrophobicContact CD1-CG2 4.2Å; Y59-V71 HydrophobicContact CE1-CG2 3.7Å; Y63-V71 HydrophobicContact CD1-CB 4.45Å; Y63-V71 HydrophobicContact CD1-CG1 3.78Å; Y63-V71 HydrophobicContact CD2-CG2 3.94Å; Y63-V71 HydrophobicContact CE1-CG1 4.48Å; Y63-V71 HydrophobicContact CG-CB 4.24Å; Y63-V71 HydrophobicContact CG-CG1 3.8Å; Y63-V71 HydrophobicContact CG-CG2 3.96Å; F68-V71 HydrophobicContact CB-CG1 4.37Å; V71-F82 HydrophobicContact CG2-CB 4.13Å; V71-F82 HydrophobicContact CG2-CD1 4Å; V71-F82 HydrophobicContact CG2-CG 4.49Å; V71-F82 PolarHBondContact N-O 2.92Å; V71-F82 PolarHBondContact O-N 2.88Å; V71-V84 HydrophobicContact CG1-CG2 4.35Å; V71-V84 HydrophobicContact CG2-CG2 3.81Å
72G97.8Very high94.7Very high0 Ų031.9 Ų31.90%017%0.165CC..EExtended strand (participates in β ladder)trans-74.6137176.800000110.5W26 V31 P32 H33 Y59W26-G72 VanDerWaalsContact CD1-CA 3.44Å; W26-G72 VanDerWaalsContact CD2-CA 3.42Å; W26-G72 VanDerWaalsContact CE2-CA 3.44Å; W26-G72 VanDerWaalsContact CG-CA 3.49Å; V31-G72 VanDerWaalsContact CG1-N 3.32Å; P32-G72 PolarHBondContact O-N 3.48Å; H33-G72 WeakPolarHBondContact CB-O 3.3Å; Y59-G72 PolarHBondContact OH-O 3.49Å
73F97.3Very high94.7Very high0 Ų026.2 Ų26.20%014%0.14CC..EExtended strand (participates in β ladder)trans-136.3155.7174.4-177-93000109.6W26 N42 M43 F56 Y59 F75 P79 A80 F82 I404W26-F73 PolarHBondContact NE1-O 3.24Å; W26-F73 VanDerWaalsContact NE1-O 3.16Å; N42-F73 HydrophobicContact CB-CD2 3.79Å; N42-F73 HydrophobicContact CB-CE2 3.57Å; N42-F73 HydrophobicContact CB-CZ 4.13Å; M43-F73 HydrophobicContact CG-CE1 4.18Å; M43-F73 HydrophobicContact CG-CZ 3.63Å; M43-F73 HydrophobicContact SD-CE1 4.11Å; M43-F73 HydrophobicContact SD-CZ 4.11Å; F56-F73 HydrophobicContact CD1-CZ 4.34Å; F56-F73 HydrophobicContact CE1-CE1 4.24Å; F56-F73 AromaticContact CE1-CZ 3.92Å; F56-F73 HydrophobicContact CE1-CZ 3.92Å; Y59-F73 AromaticContact CD1-CD2 3.78Å; Y59-F73 HydrophobicContact CD1-CD2 3.78Å; Y59-F73 HydrophobicContact CD1-CE2 4.41Å; Y59-F73 HydrophobicContact CD2-CD2 4.16Å; Y59-F73 HydrophobicContact CD2-CE2 4.3Å; Y59-F73 HydrophobicContact CE1-CB 4.22Å; Y59-F73 AromaticContact CE1-CD2 3.72Å; Y59-F73 HydrophobicContact CE1-CD2 3.72Å; Y59-F73 HydrophobicContact CE1-CG 4.48Å; Y59-F73 HydrophobicContact CE2-CD2 4.12Å; Y59-F73 HydrophobicContact CG-CD2 4Å; Y59-F73 HydrophobicContact CG-CE2 4.21Å; Y59-F73 AromaticContact CZ-CD2 3.9Å; F73-F75 HydrophobicContact CD1-CB 4.32Å; F73-F75 HydrophobicContact CE1-CB 4.02Å; F73-F75 HydrophobicContact CE1-CD2 4.18Å; F73-P79 CarbonylContact O-C 3.5Å; F73-P79 WeakPolarHBondContact O-CA 3.37Å; F73-A80 HydrophobicContact CD1-CB 4.46Å; F73-A80 PolarHBondContact N-O 2.65Å; F73-A80 PolarHBondContact O-N 3.21Å; F73-A80 VanDerWaalsContact O-O 3.08Å; F73-F82 HydrophobicContact CB-CB 3.67Å; F73-F82 HydrophobicContact CB-CD2 4.44Å; F73-F82 HydrophobicContact CB-CG 4.4Å; F73-F82 HydrophobicContact CD2-CD2 4.2Å; F73-F82 HydrophobicContact CG-CB 4.39Å; F73-F82 HydrophobicContact CG-CD2 4.27Å; F73-I404 HydrophobicContact CD1-CD1 3.59Å; F73-I404 HydrophobicContact CE1-CD1 3.81Å
74Y94.6Very high94.7Very high0 Ų025.5 Ų25.50%014%0.138CC..EExtended strand (participates in β ladder)trans-121.6104.5175-72.8-87.5000109.4N22 F23 Y25 W26 P36 N42 L76 K78 P79N22-Y74 VanDerWaalsContact O-CE1 3.29Å; N22-Y74 WeakPolarHBondContact O-CE1 3.2Å; N22-Y74 PolarHBondContact O-OH 3.4Å; F23-Y74 VanDerWaalsContact C-OH 3.24Å; F23-Y74 PolarHBondContact O-OH 3.31Å; Y25-Y74 WeakPolarHBondContact CB-OH 3.45Å; Y25-Y74 PolarHBondContact N-OH 2.93Å; W26-Y74 AromaticContact CD1-CE2 3.44Å; W26-Y74 VanDerWaalsContact CD1-CE2 3.44Å; W26-Y74 AromaticContact CD1-CZ 3.65Å; W26-Y74 HydrophobicContact CG-CE2 4.47Å; P36-Y74 HydrophobicContact CB-CD1 4.34Å; P36-Y74 HydrophobicContact CB-CD2 3.54Å; P36-Y74 HydrophobicContact CB-CE2 4.15Å; P36-Y74 HydrophobicContact CB-CG 3.64Å; P36-Y74 HydrophobicContact CG-CD1 4.41Å; P36-Y74 HydrophobicContact CG-CD2 3.57Å; P36-Y74 HydrophobicContact CG-CE1 4.49Å; P36-Y74 HydrophobicContact CG-CE2 3.63Å; P36-Y74 HydrophobicContact CG-CG 3.97Å; N42-Y74 PolarHBondContact N-O 3.3Å; N42-Y74 WeakPolarHBondContact OD1-CB 3.42Å; N42-Y74 PolarHBondContact OD1-N 3Å; Y74-L76 PolarHBondContact O-N 3.17Å; Y74-K78 CarbonylContact C-O 3.58Å; Y74-K78 VanDerWaalsContact CA-O 3.32Å; Y74-K78 WeakPolarHBondContact CA-O 3.39Å; Y74-P79 HydrophobicContact CD1-CB 4.3Å; Y74-P79 HydrophobicContact CE1-CB 3.88Å
75F88.6Confident94.8Very high36 Ų3626.4 Ų26.416%0.15815%0.146CC..EExtended strand (participates in β ladder)trans-80.9101.1170.4-166.1-77.7000108M43 F56 F73 H77 K78 I404M43-F75 HydrophobicContact CE-CD2 4.29Å; M43-F75 HydrophobicContact CE-CE1 4.24Å; M43-F75 HydrophobicContact CE-CE2 3.85Å; M43-F75 HydrophobicContact CE-CZ 3.82Å; M43-F75 HydrophobicContact SD-CB 4.42Å; M43-F75 HydrophobicContact SD-CD1 4.26Å; M43-F75 HydrophobicContact SD-CD2 3.34Å; M43-F75 WeakPolarHBondContact SD-CD2 3.36Å; M43-F75 HydrophobicContact SD-CE1 4.35Å; M43-F75 HydrophobicContact SD-CE2 3.47Å; M43-F75 WeakPolarHBondContact SD-CE2 3.3Å; M43-F75 HydrophobicContact SD-CG 3.77Å; M43-F75 HydrophobicContact SD-CZ 3.98Å; F56-F75 HydrophobicContact CZ-CE2 4.47Å; F73-F75 HydrophobicContact CD1-CB 4.32Å; F73-F75 HydrophobicContact CE1-CB 4.02Å; F73-F75 HydrophobicContact CE1-CD2 4.18Å; F75-H77 PolarHBondContact O-N 2.92Å; F75-K78 PolarHBondContact N-O 3.04Å; F75-K78 PolarHBondContact O-N 2.87Å; F75-I404 HydrophobicContact CB-CD1 4.38Å; F75-I404 HydrophobicContact CD2-CD1 4.17Å
76L86.3Confident94.9Very high5 Ų520.6 Ų20.63%0.02612%0.123CC..THydrogen-bonded Turntrans53.6-118.8-163.1-56.3175000109.7Y40 G41 F46 Y74 M225Y40-L76 HydrophobicContact CD1-CD2 4.48Å; G41-L76 WeakPolarHBondContact CA-O 3.41Å; G41-L76 PolarHBondContact N-O 3.48Å; F46-L76 HydrophobicContact CD1-CD2 4.39Å; Y74-L76 PolarHBondContact O-N 3.17Å; L76-M225 HydrophobicContact CD1-CB 4.36Å; L76-M225 HydrophobicContact CD1-CG 4.19Å
77H83.8Confident95Very high36 Ų3622 Ų2217%0.16713%0.125CC..THydrogen-bonded Turntrans-91.6-4.6176.771.4-35.2000113N22 F23 F75 S229 F230N22-H77 PolarHBondContact ND2-O 2.92Å; F23-H77 HydrophobicContact CE2-CB 3.93Å; F23-H77 HydrophobicContact CZ-CB 4.22Å; F75-H77 PolarHBondContact O-N 2.92Å; H77-S229 WeakPolarHBondContact CE1-CA 3Å; H77-S229 WeakPolarHBondContact CE1-CB 3.37Å; H77-S229 PolarHBondContact CE1-O 3.17Å; H77-S229 PolarHBondContact CE1-OG 3.29Å; H77-S229 VanDerWaalsContact CE1-OG 3.25Å; H77-S229 WeakPolarHBondContact ND1-CB 3.26Å; H77-S229 PolarHBondContact ND1-OG 3.47Å; H77-S229 PolarHBondContact NE2-O 3.13Å; H77-S229 VanDerWaalsContact NE2-O 3.17Å; H77-F230 AromaticContact CD2-CE1 3.82Å; H77-F230 AromaticContact CD2-CE2 3.92Å; H77-F230 AromaticContact CD2-CZ 3.33Å; H77-F230 WeakPolarHBondContact CD2-CZ 3.3Å; H77-F230 AromaticContact NE2-CD1 3.9Å; H77-F230 AromaticContact NE2-CE1 3.32Å; H77-F230 VanDerWaalsContact NE2-CE1 3.32Å; H77-F230 WeakPolarHBondContact NE2-CE1 3.4Å; H77-F230 AromaticContact NE2-CE2 3.54Å; H77-F230 AromaticContact NE2-CZ 3.13Å; H77-F230 WeakPolarHBondContact NE2-CZ 3.47Å
78K87.9Confident95.3Very high54 Ų5419 Ų1924%0.2359%0.093CC..EExtended strand (participates in β ladder)trans-89.1128.4-177.7-69.7-175.81791670112.2Y74 F75 F228 S229 P231Y74-K78 CarbonylContact C-O 3.58Å; Y74-K78 VanDerWaalsContact CA-O 3.32Å; Y74-K78 WeakPolarHBondContact CA-O 3.39Å; F75-K78 PolarHBondContact N-O 3.04Å; F75-K78 PolarHBondContact O-N 2.87Å; K78-F228 WeakPolarHBondContact CE-O 3.18Å; K78-F228 PolarHBondContact NZ-O 3.41Å; K78-S229 WeakPolarHBondContact CE-O 3.15Å; K78-P231 VanDerWaalsContact NZ-CD 3.25Å
79P94.1Very high95.4Very high23 Ų2315.6 Ų15.615%0.1498%0.078CC..EExtended strand (participates in β ladder)trans-65.7136.8168.228.3-32.9000110.4N22 Y25 W26 F73 Y74N22-P79 WeakPolarHBondContact OD1-CD 3.49Å; Y25-P79 HydrophobicContact CD1-CB 3.63Å; Y25-P79 HydrophobicContact CD1-CG 4.17Å; Y25-P79 HydrophobicContact CD2-CG 4.37Å; Y25-P79 HydrophobicContact CE1-CB 4.16Å; Y25-P79 HydrophobicContact CG-CB 3.96Å; Y25-P79 HydrophobicContact CG-CG 4.07Å; W26-P79 HydrophobicContact CZ2-CB 4.33Å; F73-P79 CarbonylContact O-C 3.5Å; F73-P79 WeakPolarHBondContact O-CA 3.37Å; Y74-P79 HydrophobicContact CD1-CB 4.3Å; Y74-P79 HydrophobicContact CE1-CB 3.88Å
80A96.8Very high95.4Very high0 Ų017.5 Ų17.50%09%0.086CC..EExtended strand (participates in β ladder)trans-138.5140.4177.200000110W26 F73 F82 Q402 I404W26-A80 WeakPolarHBondContact CZ2-O 3.31Å; F73-A80 HydrophobicContact CD1-CB 4.46Å; F73-A80 PolarHBondContact N-O 2.65Å; F73-A80 PolarHBondContact O-N 3.21Å; F73-A80 VanDerWaalsContact O-O 3.08Å; A80-F82 PolarHBondContact O-N 3.42Å; A80-Q402 CarbonylContact C-O 3.55Å; A80-Q402 WeakPolarHBondContact CA-O 3.27Å; A80-Q402 HydrophobicContact CB-CB 3.92Å; A80-I404 HydrophobicContact CB-CD1 3.69Å; A80-I404 HydrophobicContact CB-CG1 4.08Å
81A98.4Very high95.4Very high0 Ų018.2 Ų18.20%09%0.09CC..EExtended strand (participates in β ladder)trans-78.3114.6170.200000108W26 F70 I83 I397 T401 Q402 V403 I404W26-A81 HydrophobicContact CH2-CB 4.02Å; W26-A81 HydrophobicContact CZ2-CB 4.44Å; F70-A81 HydrophobicContact CD2-CB 3.83Å; F70-A81 HydrophobicContact CE2-CB 4.21Å; F70-A81 HydrophobicContact CG-CB 4.35Å; A81-I83 HydrophobicContact CB-CD1 4.42Å; A81-I397 HydrophobicContact CB-CD1 4.27Å; A81-I397 HydrophobicContact CB-CG1 4.26Å; A81-I397 HydrophobicContact CB-CG2 4.28Å; A81-T401 HydrophobicContact CB-CG2 4.31Å; A81-Q402 PolarHBondContact N-O 3.45Å; A81-V403 HydrophobicContact CB-CG2 4.4Å; A81-V403 CarbonylContact O-C 3.56Å; A81-V403 WeakPolarHBondContact O-CA 3.23Å; A81-I404 PolarHBondContact O-N 3.49Å
82F98.6Very high95.4Very high0 Ų018.2 Ų18.20%09%0.09CC..EExtended strand (participates in β ladder)trans-94.3110.4177.8-173.9-86.7000108.8F56 Y59 Y60 F70 V71 F73 A80 V84 I404 P406F56-F82 HydrophobicContact CB-CE2 4.2Å; F56-F82 HydrophobicContact CB-CZ 4.29Å; F56-F82 HydrophobicContact CD1-CD2 4.46Å; F56-F82 AromaticContact CD1-CE2 3.63Å; F56-F82 HydrophobicContact CD1-CE2 3.63Å; F56-F82 HydrophobicContact CD1-CZ 4.49Å; F56-F82 HydrophobicContact CE1-CE2 4.4Å; F56-F82 HydrophobicContact CG-CE2 4.23Å; Y59-F82 AromaticContact CD1-CD1 3.91Å; Y59-F82 HydrophobicContact CD1-CD1 3.91Å; Y59-F82 HydrophobicContact CD1-CD2 4.4Å; Y59-F82 HydrophobicContact CD1-CE1 4.09Å; Y59-F82 HydrophobicContact CD1-CG 4.06Å; Y59-F82 HydrophobicContact CD1-CZ 4.41Å; Y59-F82 HydrophobicContact CE1-CG 4.47Å; Y60-F82 HydrophobicContact CD2-CE1 4.29Å; F70-F82 CarbonylContact C-O 3.06Å; F70-F82 VanDerWaalsContact CA-O 3.25Å; F70-F82 WeakPolarHBondContact CA-O 3.32Å; F70-F82 WeakPolarHBondContact CB-O 3.37Å; V71-F82 HydrophobicContact CG2-CB 4.13Å; V71-F82 HydrophobicContact CG2-CD1 4Å; V71-F82 HydrophobicContact CG2-CG 4.49Å; V71-F82 PolarHBondContact N-O 2.92Å; V71-F82 PolarHBondContact O-N 2.88Å; F73-F82 HydrophobicContact CB-CB 3.67Å; F73-F82 HydrophobicContact CB-CD2 4.44Å; F73-F82 HydrophobicContact CB-CG 4.4Å; F73-F82 HydrophobicContact CD2-CD2 4.2Å; F73-F82 HydrophobicContact CG-CB 4.39Å; F73-F82 HydrophobicContact CG-CD2 4.27Å; A80-F82 PolarHBondContact O-N 3.42Å; F82-V84 HydrophobicContact CD1-CG2 4.06Å; F82-V84 HydrophobicContact CE1-CG2 4.48Å; F82-I404 HydrophobicContact CD2-CB 4.1Å; F82-I404 HydrophobicContact CD2-CG2 3.73Å; F82-I404 HydrophobicContact CE2-CG2 3.94Å; F82-P406 HydrophobicContact CE1-CB 4.2Å; F82-P406 HydrophobicContact CE1-CG 3.73Å; F82-P406 HydrophobicContact CE2-CB 3.81Å; F82-P406 HydrophobicContact CE2-CG 4.12Å; F82-P406 HydrophobicContact CZ-CB 3.41Å; F82-P406 VanDerWaalsContact CZ-CB 3.41Å; F82-P406 HydrophobicContact CZ-CG 3.47Å; F82-P406 VanDerWaalsContact CZ-CG 3.47Å
83I98.6Very high95.5Very high0 Ų018.2 Ų18.20%09%0.09CC..EExtended strand (participates in β ladder)trans-77.5130.1-173.1-50.5-51.9000109F70 A81 D85 L88 A89 I92 I397 V403 I404 I405 P406 Y410F70-I83 HydrophobicContact CB-CD1 3.72Å; A81-I83 HydrophobicContact CB-CD1 4.42Å; I83-D85 VanDerWaalsContact CG2-O 3.29Å; I83-D85 WeakPolarHBondContact CG2-O 3.43Å; I83-L88 HydrophobicContact CD1-CD2 3.88Å; I83-L88 HydrophobicContact CD1-CG 4.32Å; I83-L88 HydrophobicContact CG2-CB 4.11Å; I83-L88 HydrophobicContact CG2-CD2 4.23Å; I83-L88 HydrophobicContact CG2-CG 4.07Å; I83-A89 HydrophobicContact CG2-CB 4.1Å; I83-I92 HydrophobicContact CD1-CD1 3.65Å; I83-I92 HydrophobicContact CG1-CD1 3.93Å; I83-I397 HydrophobicContact CD1-CD1 4.3Å; I83-V403 HydrophobicContact CD1-CG1 3.78Å; I83-V403 HydrophobicContact CG1-CG1 3.53Å; I83-I404 PolarHBondContact N-O 3.12Å; I83-I405 HydrophobicContact CB-CG1 4.12Å; I83-I405 HydrophobicContact CG1-CG1 3.87Å; I83-P406 WeakPolarHBondContact O-CD 3.33Å; I83-P406 WeakPolarHBondContact O-CG 3.12Å; I83-Y410 PolarHBondContact O-OH 3.15Å
84V97.6Very high95.5Very high8 Ų821.2 Ų21.25%0.04811%0.105CC..  trans-113.7-35.3-176.4178.10000110.2Y60 R64 P69 V71 F82Y60-V84 HydrophobicContact CD2-CG1 4.36Å; Y60-V84 HydrophobicContact CE2-CG1 4.02Å; Y60-V84 WeakPolarHBondContact CE2-O 3.42Å; R64-V84 HydrophobicContact CB-CG1 4Å; P69-V84 PolarHBondContact O-N 2.7Å; V71-V84 HydrophobicContact CG1-CG2 4.35Å; V71-V84 HydrophobicContact CG2-CG2 3.81Å; F82-V84 HydrophobicContact CD1-CG2 4.06Å; F82-V84 HydrophobicContact CE1-CG2 4.48Å
85D97.1Very high95.7Very high58 Ų5827.2 Ų27.231%0.3113%0.131SC..  trans-86.5127.5176.517030.3000111.6P69 I83 Q87 L88 A89P69-D85 HydrophobicContact CB-CB 3.99Å; P69-D85 PolarHBondContact O-N 3.23Å; I83-D85 VanDerWaalsContact CG2-O 3.29Å; I83-D85 WeakPolarHBondContact CG2-O 3.43Å; D85-Q87 VanDerWaalsContact C-N 3.27Å; D85-Q87 PolarHBondContact O-N 2.9Å; D85-Q87 WeakPolarHBondContact OD1-CB 3.31Å; D85-Q87 PolarHBondContact OD1-N 3.45Å; D85-L88 HydrophobicContact CB-CB 4.25Å; D85-L88 PolarHBondContact O-N 2.95Å; D85-L88 PolarHBondContact OD2-N 3.07Å; D85-A89 PolarHBondContact O-N 3.23Å
86T97.3Very high96.1Very high28 Ų2827.9 Ų27.917%0.17214%0.137CC..Hα-helixtrans-66-30176.9570000111.6A89 K90 Y410 L416 E440T86-A89 WeakPolarHBondContact O-CB 3.4Å; T86-A89 PolarHBondContact O-N 2.86Å; T86-K90 PolarHBondContact O-N 3.45Å; T86-Y410 HydrophobicContact CG2-CD2 4.04Å; T86-Y410 HydrophobicContact CG2-CE2 3.95Å; T86-Y410 HydrophobicContact CG2-CG 4.35Å; T86-L416 HydrophobicContact CG2-CD1 4.07Å; T86-E440 HydrophobicContact CG2-CG 4.39Å
87Q97.1Very high96.7Very high74 Ų7428.9 Ų28.935%0.34614%0.141SC..Hα-helixtrans-69.4-40.1177.2-175.85467.700111.6D85 A89 K90 N91D85-Q87 VanDerWaalsContact C-N 3.27Å; D85-Q87 PolarHBondContact O-N 2.9Å; D85-Q87 WeakPolarHBondContact OD1-CB 3.31Å; D85-Q87 PolarHBondContact OD1-N 3.45Å; Q87-A89 VanDerWaalsContact C-N 3.33Å; Q87-K90 WeakPolarHBondContact O-CB 3.4Å; Q87-K90 PolarHBondContact O-N 2.96Å; Q87-N91 PolarHBondContact NE2-OD1 3Å; Q87-N91 VanDerWaalsContact NE2-OD1 3.12Å; Q87-N91 VanDerWaalsContact O-CG 3.32Å; Q87-N91 PolarHBondContact O-N 3.46Å; Q87-N91 PolarHBondContact O-OD1 3.37Å
88L98.4Very high97.3Very high2 Ų232 Ų321%0.0117%0.167CC..Hα-helixtrans-62.7-39.6168.718055.9000111.6P69 F70 I83 D85 K90 N91 I92 Y387 V389P69-L88 HydrophobicContact CB-CB 4.35Å; P69-L88 HydrophobicContact CB-CD2 3.85Å; P69-L88 HydrophobicContact CG-CD2 4.43Å; F70-L88 HydrophobicContact CB-CD2 4.12Å; F70-L88 HydrophobicContact CD1-CD2 4.01Å; I83-L88 HydrophobicContact CD1-CD2 3.88Å; I83-L88 HydrophobicContact CD1-CG 4.32Å; I83-L88 HydrophobicContact CG2-CB 4.11Å; I83-L88 HydrophobicContact CG2-CD2 4.23Å; I83-L88 HydrophobicContact CG2-CG 4.07Å; D85-L88 HydrophobicContact CB-CB 4.25Å; D85-L88 PolarHBondContact O-N 2.95Å; D85-L88 PolarHBondContact OD2-N 3.07Å; L88-K90 VanDerWaalsContact C-N 3.33Å; L88-K90 PolarHBondContact O-N 3.47Å; L88-N91 PolarHBondContact O-N 3.4Å; L88-I92 HydrophobicContact CD1-CD1 3.85Å; L88-I92 HydrophobicContact CD1-CG1 4.08Å; L88-I92 HydrophobicContact CD2-CD1 4.44Å; L88-I92 HydrophobicContact CG-CD1 3.8Å; L88-I92 HydrophobicContact CG-CG1 4.45Å; L88-I92 WeakPolarHBondContact O-CG1 3.39Å; L88-I92 PolarHBondContact O-N 3.48Å; L88-Y387 HydrophobicContact CD1-CE1 3.86Å; L88-V389 HydrophobicContact CD1-CG1 4.11Å; L88-V389 HydrophobicContact CD1-CG2 4.44Å; L88-V389 HydrophobicContact CD2-CG1 4.19Å; L88-V389 HydrophobicContact CD2-CG2 4.25Å
89A98.6Very high97.8Very high0 Ų030.2 Ų30.20%016%0.16CC..Hα-helixtrans-60.1-41.717400000112.1I83 D85 T86 Q87 N91 I92 L93 I405 Y410I83-A89 HydrophobicContact CG2-CB 4.1Å; D85-A89 PolarHBondContact O-N 3.23Å; T86-A89 WeakPolarHBondContact O-CB 3.4Å; T86-A89 PolarHBondContact O-N 2.86Å; Q87-A89 VanDerWaalsContact C-N 3.33Å; A89-N91 VanDerWaalsContact C-N 3.34Å; A89-N91 PolarHBondContact O-N 3.43Å; A89-I92 PolarHBondContact O-N 3.39Å; A89-L93 WeakPolarHBondContact O-CB 3.38Å; A89-L93 VanDerWaalsContact O-CG 3.26Å; A89-L93 WeakPolarHBondContact O-CG 3.38Å; A89-L93 PolarHBondContact O-N 3.18Å; A89-I405 HydrophobicContact CB-CD1 4.43Å; A89-I405 HydrophobicContact CB-CG1 4.41Å; A89-I405 HydrophobicContact CB-CG2 3.99Å; A89-Y410 HydrophobicContact CB-CE2 3.98Å
90K98.4Very high98Very high43 Ų4329.1 Ų29.119%0.18715%0.153CC..Hα-helixtrans-59.5-42.2173.3-171.9170.9178.8176.20112.4T86 Q87 L88 I94 K95 E437 V439T86-K90 PolarHBondContact O-N 3.45Å; Q87-K90 WeakPolarHBondContact O-CB 3.4Å; Q87-K90 PolarHBondContact O-N 2.96Å; L88-K90 VanDerWaalsContact C-N 3.33Å; L88-K90 PolarHBondContact O-N 3.47Å; K90-I94 HydrophobicContact CG-CD1 4.16Å; K90-I94 WeakPolarHBondContact O-CB 3.45Å; K90-I94 PolarHBondContact O-N 2.98Å; K90-K95 PolarHBondContact O-N 2.96Å; K90-E437 VanDerWaalsContact NZ-CD 3.25Å; K90-E437 IonicContact NZ-OE1 3.11Å; K90-E437 PolarHBondContact NZ-OE1 3.35Å; K90-E437 VanDerWaalsContact NZ-OE1 3.16Å; K90-E437 IonicContact NZ-OE2 3.21Å; K90-E437 PolarHBondContact NZ-OE2 2.84Å; K90-V439 HydrophobicContact CB-CG1 3.99Å; K90-V439 HydrophobicContact CB-CG2 3.9Å; K90-V439 HydrophobicContact CG-CG1 4.34Å
91N98.4Very high98Very high15 Ų1529.9 Ų29.98%0.0816%0.159CC..Iπ-helixtrans-62.9-50176.6-64.5-9.3000110.5Q87 L88 A89 L93 K95 D96Q87-N91 PolarHBondContact NE2-OD1 3Å; Q87-N91 VanDerWaalsContact NE2-OD1 3.12Å; Q87-N91 VanDerWaalsContact O-CG 3.32Å; Q87-N91 PolarHBondContact O-N 3.46Å; Q87-N91 PolarHBondContact O-OD1 3.37Å; L88-N91 PolarHBondContact O-N 3.4Å; A89-N91 VanDerWaalsContact C-N 3.34Å; A89-N91 PolarHBondContact O-N 3.43Å; N91-L93 PolarHBondContact O-N 3.37Å; N91-K95 PolarHBondContact O-N 2.65Å; N91-K95 VanDerWaalsContact O-N 3.14Å; N91-K95 WeakPolarHBondContact OD1-CD 3.37Å; N91-D96 PolarHBondContact O-N 3.11Å
92I98.6Very high98Very high0 Ų030.9 Ų30.90%016%0.164CC..Iπ-helixtrans-64.1-42.6-177.9-69.9170.7000112.6I83 L88 A89 F100 R381 I397 V403 I405I83-I92 HydrophobicContact CD1-CD1 3.65Å; I83-I92 HydrophobicContact CG1-CD1 3.93Å; L88-I92 HydrophobicContact CD1-CD1 3.85Å; L88-I92 HydrophobicContact CD1-CG1 4.08Å; L88-I92 HydrophobicContact CD2-CD1 4.44Å; L88-I92 HydrophobicContact CG-CD1 3.8Å; L88-I92 HydrophobicContact CG-CG1 4.45Å; L88-I92 WeakPolarHBondContact O-CG1 3.39Å; L88-I92 PolarHBondContact O-N 3.48Å; A89-I92 PolarHBondContact O-N 3.39Å; I92-F100 HydrophobicContact CB-CD2 4.18Å; I92-F100 HydrophobicContact CB-CE2 4.44Å; I92-F100 HydrophobicContact CB-CG 4.41Å; I92-F100 HydrophobicContact CG1-CD2 4.05Å; I92-F100 HydrophobicContact CG1-CE1 4.38Å; I92-F100 HydrophobicContact CG1-CE2 3.81Å; I92-F100 HydrophobicContact CG1-CG 4.46Å; I92-F100 HydrophobicContact CG1-CZ 3.98Å; I92-F100 HydrophobicContact CG2-CB 3.96Å; I92-F100 HydrophobicContact CG2-CD1 4.07Å; I92-F100 HydrophobicContact CG2-CD2 4.05Å; I92-F100 HydrophobicContact CG2-CG 3.77Å; I92-R381 HydrophobicContact CG2-CB 4.23Å; I92-R381 HydrophobicContact CG2-CG 3.97Å; I92-I397 HydrophobicContact CD1-CD1 4.19Å; I92-V403 HydrophobicContact CD1-CG1 3.96Å; I92-V403 HydrophobicContact CG2-CG1 4.28Å; I92-I405 HydrophobicContact CG2-CD1 4.13Å
93L98.6Very high97.8Very high0 Ų032.4 Ų32.40%017%0.17CC..Iπ-helixtrans-78.9-33.7-175.6-67.2176.1000112.9A89 N91 L379 R381 I405 V439 L442 D446 G447A89-L93 WeakPolarHBondContact O-CB 3.38Å; A89-L93 VanDerWaalsContact O-CG 3.26Å; A89-L93 WeakPolarHBondContact O-CG 3.38Å; A89-L93 PolarHBondContact O-N 3.18Å; N91-L93 PolarHBondContact O-N 3.37Å; L93-L379 HydrophobicContact CD1-CD1 3.98Å; L93-L379 HydrophobicContact CD2-CD1 4.1Å; L93-R381 HydrophobicContact CD2-CG 4.48Å; L93-R381 VanDerWaalsContact CD2-NH2 3.28Å; L93-I405 HydrophobicContact CD1-CD1 3.96Å; L93-I405 HydrophobicContact CD2-CD1 3.54Å; L93-I405 HydrophobicContact CG-CD1 3.61Å; L93-V439 HydrophobicContact CD1-CG1 4.19Å; L93-L442 HydrophobicContact CD1-CD1 4.28Å; L93-L442 HydrophobicContact CD1-CD2 3.9Å; L93-D446 HydrophobicContact CD1-CB 4.22Å; L93-G447 WeakPolarHBondContact O-CA 3.08Å
94I98.2Very high97.4Very high63 Ų6333.1 Ų33.132%0.32318%0.177SC..Iπ-helixtrans-121.7-66.3-168.5-58.8160.1000111.8K90 F97 V439K90-I94 HydrophobicContact CG-CD1 4.16Å; K90-I94 WeakPolarHBondContact O-CB 3.45Å; K90-I94 PolarHBondContact O-N 2.98Å; I94-F97 WeakPolarHBondContact O-CB 3.44Å; I94-V439 HydrophobicContact CD1-CG1 4.16Å
95K97.9Very high96.9Very high126 Ų12634.6 Ų34.655%0.54818%0.183SC..Iπ-helixtrans-67.6-47.6-166.9-59.9-173.1-173.7164.50112.6K90 N91K90-K95 PolarHBondContact O-N 2.96Å; N91-K95 PolarHBondContact O-N 2.65Å; N91-K95 VanDerWaalsContact O-N 3.14Å; N91-K95 WeakPolarHBondContact OD1-CD 3.37Å
96D97.9Very high96.5Very high51 Ų5132.1 Ų32.127%0.27317%0.17SC..THydrogen-bonded Turntrans-105.324.5-175.8-56.6-42.7000111.4N91 S98 N99 F100 Y387N91-D96 PolarHBondContact O-N 3.11Å; D96-S98 PolarHBondContact O-N 2.97Å; D96-N99 PolarHBondContact O-N 3.1Å; D96-F100 HydrophobicContact CB-CD2 4.37Å; D96-F100 HydrophobicContact CB-CE2 4.36Å; D96-F100 WeakPolarHBondContact O-CD2 3.2Å; D96-Y387 HydrophobicContact CB-CE2 3.88Å; D96-Y387 VanDerWaalsContact OD2-CE2 3.3Å; D96-Y387 WeakPolarHBondContact OD2-CE2 3.46Å; D96-Y387 PolarHBondContact OD2-OH 3.31Å
97F97.8Very high96.1Very high26 Ų2633.9 Ų33.911%0.11418%0.176CC..G310 helixtrans-52.4-32.1-176.6175-98.4000113I94 N99 F100 A101 W126 P448 R449I94-F97 WeakPolarHBondContact O-CB 3.44Å; F97-N99 PolarHBondContact O-N 2.82Å; F97-F100 CarbonylContact O-C 3.57Å; F97-F100 PolarHBondContact O-N 3.08Å; F97-A101 HydrophobicContact CE1-CB 3.98Å; F97-A101 HydrophobicContact CZ-CB 3.94Å; F97-A101 WeakPolarHBondContact O-CA 3.43Å; F97-A101 PolarHBondContact O-N 3.38Å; F97-W126 AromaticContact CE1-CH2 3.9Å; F97-W126 HydrophobicContact CE1-CH2 3.9Å; F97-W126 AromaticContact CE1-CZ3 3.98Å; F97-W126 HydrophobicContact CE1-CZ3 3.98Å; F97-W126 AromaticContact CZ-CH2 3.44Å; F97-W126 HydrophobicContact CZ-CH2 3.44Å; F97-W126 VanDerWaalsContact CZ-CH2 3.44Å; F97-W126 HydrophobicContact CZ-CZ2 4.31Å; F97-W126 AromaticContact CZ-CZ3 3.74Å; F97-W126 HydrophobicContact CZ-CZ3 3.74Å; F97-P448 HydrophobicContact CB-CG 4.42Å; F97-P448 HydrophobicContact CD1-CB 3.92Å; F97-P448 HydrophobicContact CD1-CG 3.65Å; F97-P448 HydrophobicContact CD2-CB 4.48Å; F97-P448 HydrophobicContact CD2-CG 4.26Å; F97-P448 HydrophobicContact CE1-CB 3.69Å; F97-P448 HydrophobicContact CE1-CG 3.98Å; F97-P448 HydrophobicContact CE2-CB 4.28Å; F97-P448 HydrophobicContact CG-CB 4.32Å; F97-P448 HydrophobicContact CG-CG 3.81Å; F97-P448 HydrophobicContact CZ-CB 3.9Å; F97-P448 HydrophobicContact CZ-CG 4.43Å; F97-R449 HydrophobicContact CE2-CB 3.65Å; F97-R449 HydrophobicContact CZ-CB 3.91Å
98S97.4Very high95.7Very high101 Ų10130.7 Ų30.771%0.70616%0.162SC*.G310 helixtrans-57.4-32.2177.358.80000113D96D96-S98 PolarHBondContact O-N 2.97Å
99N98.3Very high95.1Very high16 Ų1631.7 Ų31.79%0.08617%0.172CC..G310 helixtrans-86.1-13.3175.8-164.245000113.4D96 F97 L384 N385D96-N99 PolarHBondContact O-N 3.1Å; F97-N99 PolarHBondContact O-N 2.82Å; N99-L384 WeakPolarHBondContact O-CB 3.43Å; N99-L384 WeakPolarHBondContact O-CG 3.32Å; N99-L384 PolarHBondContact O-N 3.46Å; N99-N385 PolarHBondContact ND2-O 3.27Å; N99-N385 WeakPolarHBondContact OD1-CA 3.34Å; N99-N385 VanDerWaalsContact OD1-CB 3.26Å; N99-N385 WeakPolarHBondContact OD1-CB 3.35Å; N99-N385 PolarHBondContact OD1-N 3.1Å; N99-N385 PolarHBondContact OD1-ND2 3.44Å; N99-N385 PolarHBondContact OD1-O 3.3Å
100F98.4Very high94.5Very high0 Ų040.3 Ų40.30%020%0.204CC..SBendtrans-126.935-176.3-60.8-76.6000110.7I92 D96 F97 D102 R381 A383 Y387 V403I92-F100 HydrophobicContact CB-CD2 4.18Å; I92-F100 HydrophobicContact CB-CE2 4.44Å; I92-F100 HydrophobicContact CB-CG 4.41Å; I92-F100 HydrophobicContact CG1-CD2 4.05Å; I92-F100 HydrophobicContact CG1-CE1 4.38Å; I92-F100 HydrophobicContact CG1-CE2 3.81Å; I92-F100 HydrophobicContact CG1-CG 4.46Å; I92-F100 HydrophobicContact CG1-CZ 3.98Å; I92-F100 HydrophobicContact CG2-CB 3.96Å; I92-F100 HydrophobicContact CG2-CD1 4.07Å; I92-F100 HydrophobicContact CG2-CD2 4.05Å; I92-F100 HydrophobicContact CG2-CG 3.77Å; D96-F100 HydrophobicContact CB-CD2 4.37Å; D96-F100 HydrophobicContact CB-CE2 4.36Å; D96-F100 WeakPolarHBondContact O-CD2 3.2Å; F97-F100 CarbonylContact O-C 3.57Å; F97-F100 PolarHBondContact O-N 3.08Å; F100-D102 VanDerWaalsContact C-N 3.27Å; F100-D102 PolarHBondContact O-N 3.43Å; F100-R381 HydrophobicContact CB-CB 4.09Å; F100-R381 HydrophobicContact CB-CG 4.28Å; F100-R381 HydrophobicContact CD1-CB 4.42Å; F100-R381 WeakPolarHBondContact O-CD 3.31Å; F100-A383 HydrophobicContact CD1-CB 4.32Å; F100-A383 HydrophobicContact CE1-CB 3.8Å; F100-Y387 HydrophobicContact CE2-CD1 4.15Å; F100-Y387 AromaticContact CE2-CD2 3.74Å; F100-Y387 HydrophobicContact CE2-CD2 3.74Å; F100-Y387 HydrophobicContact CE2-CE1 4.32Å; F100-Y387 AromaticContact CE2-CE2 3.92Å; F100-Y387 HydrophobicContact CE2-CE2 3.92Å; F100-Y387 AromaticContact CE2-CG 3.85Å; F100-Y387 HydrophobicContact CE2-CG 3.85Å; F100-Y387 AromaticContact CZ-CD1 3.76Å; F100-Y387 HydrophobicContact CZ-CD1 3.76Å; F100-Y387 AromaticContact CZ-CD2 3.95Å; F100-Y387 HydrophobicContact CZ-CD2 3.95Å; F100-Y387 HydrophobicContact CZ-CE1 4.29Å; F100-Y387 HydrophobicContact CZ-CE2 4.46Å; F100-Y387 AromaticContact CZ-CG 3.56Å; F100-Y387 HydrophobicContact CZ-CG 3.56Å; F100-V403 HydrophobicContact CD1-CG2 4.22Å; F100-V403 HydrophobicContact CE1-CG2 3.97Å
101A97.3Very high94Very high16 Ų1640.2 Ų40.213%0.13221%0.206CC..  trans-70.4-29.6-175.600000111.7F97 L384 R449F97-A101 HydrophobicContact CE1-CB 3.98Å; F97-A101 HydrophobicContact CZ-CB 3.94Å; F97-A101 WeakPolarHBondContact O-CA 3.43Å; F97-A101 PolarHBondContact O-N 3.38Å; A101-L384 HydrophobicContact CB-CD1 4.26Å; A101-R449 WeakPolarHBondContact O-CD 3.26Å; A101-R449 PolarHBondContact O-NH1 2.64Å
102D97.4Very high93.7Very high22 Ų2239.5 Ų39.512%0.11820%0.202CC..BIsolated β-bridgetrans-91.2151.2-171-74.9-3000113.6F100 D122 G123 R381 K382 L384 R449F100-D102 VanDerWaalsContact C-N 3.27Å; F100-D102 PolarHBondContact O-N 3.43Å; D102-D122 VanDerWaalsContact CA-OD1 3.31Å; D102-D122 WeakPolarHBondContact CA-OD1 3.34Å; D102-D122 HydrophobicContact CB-CB 4.18Å; D102-D122 WeakPolarHBondContact CB-OD1 3.43Å; D102-D122 VanDerWaalsContact CG-CB 3.5Å; D102-D122 WeakPolarHBondContact OD1-CB 3.14Å; D102-G123 PolarHBondContact OD1-N 2.96Å; D102-R381 CarbonylContact O-C 3.58Å; D102-R381 VanDerWaalsContact O-CA 3.25Å; D102-R381 WeakPolarHBondContact O-CA 3.39Å; D102-K382 HydrophobicContact CB-CB 4.3Å; D102-K382 PolarHBondContact O-N 3.09Å; D102-L384 HydrophobicContact CB-CD2 4Å; D102-L384 WeakPolarHBondContact OD2-CD2 2.87Å; D102-R449 IonicContact OD1-NH1 3.28Å
103R94.8Very high93.3Very high32 Ų3240.6 Ų40.612%0.12121%0.21CC..  trans-97.8-22.3168.8-69.8-177.9-176.4167-7.5112.7Q105 F119 D122 Q402 R449R103-Q105 VanDerWaalsContact C-N 3.29Å; R103-Q105 HydrophobicContact CB-CG 4.11Å; R103-Q105 PolarHBondContact O-N 2.87Å; R103-F119 PolarHBondContact NH1-O 3.04Å; R103-D122 PolarHBondContact N-OD1 2.97Å; R103-Q402 PolarHBondContact O-NE2 3.4Å; R103-R449 PolarHBondContact NH2-O 3.44Å
104G89.9Confident93.1Very high14 Ų1440.6 Ų40.614%0.14421%0.21CC..  trans70.723.2179.600000114.5D122G104-D122 VanDerWaalsContact CA-OD2 3.25Å; G104-D122 WeakPolarHBondContact CA-OD2 3.34Å; G104-D122 PolarHBondContact N-OD2 2.99Å
105Q87.5Confident92.9Very high39 Ų3937.7 Ų37.718%0.18219%0.194CC..  trans-75.9158.9-178.7-77.3-62.4-3800112.5R103 N120 E380R103-Q105 VanDerWaalsContact C-N 3.29Å; R103-Q105 HydrophobicContact CB-CG 4.11Å; R103-Q105 PolarHBondContact O-N 2.87Å; Q105-N120 HydrophobicContact CB-CB 4.33Å; Q105-E380 PolarHBondContact NE2-OE2 3Å
106F88.4Confident92.6Very high7 Ų732.6 Ų32.63%0.03117%0.173CC..  trans-71.7131.1175.4175.6-97.5000110.6N108 N120 V227 P231 A234 M241F106-N108 HydrophobicContact CE1-CB 4.21Å; F106-N108 HydrophobicContact CE2-CB 4.44Å; F106-N108 HydrophobicContact CZ-CB 3.74Å; F106-N120 PolarHBondContact O-ND2 2.81Å; F106-V227 HydrophobicContact CB-CG1 4.25Å; F106-V227 HydrophobicContact CD1-CG1 3.8Å; F106-V227 HydrophobicContact CD2-CG1 3.75Å; F106-V227 HydrophobicContact CE1-CG1 4.04Å; F106-V227 HydrophobicContact CE2-CG1 3.98Å; F106-V227 HydrophobicContact CG-CG1 3.65Å; F106-V227 HydrophobicContact CZ-CG1 4.12Å; F106-P231 HydrophobicContact CB-CB 4.03Å; F106-P231 HydrophobicContact CD2-CB 3.81Å; F106-P231 HydrophobicContact CG-CB 4.43Å; F106-A234 HydrophobicContact CD2-CB 4.47Å; F106-A234 HydrophobicContact CE2-CB 3.93Å; F106-M241 HydrophobicContact CD1-CB 4.2Å; F106-M241 HydrophobicContact CD1-CE 4.28Å; F106-M241 HydrophobicContact CD1-SD 4.14Å; F106-M241 HydrophobicContact CE1-CB 4.01Å
107H88.4Confident92.4Very high64 Ų6431 Ų3130%0.29616%0.163SC..  trans-146.9141.9163.36382.9000110T115 N120H107-T115 WeakPolarHBondContact CB-O 3.46Å; H107-N120 HydrophobicContact CB-CB 4.19Å; H107-N120 PolarHBondContact CD2-O 3.27Å
108N88.8Confident92.3Very high8 Ų830.2 Ų30.24%0.04316%0.161CC..BIsolated β-bridgetrans-133.882.9175.4-1776.7000109.7F106 R110 D111 D112 T115 M239F106-N108 HydrophobicContact CE1-CB 4.21Å; F106-N108 HydrophobicContact CE2-CB 4.44Å; F106-N108 HydrophobicContact CZ-CB 3.74Å; N108-R110 PolarHBondContact O-N 3.27Å; N108-R110 PolarHBondContact OD1-N 3.11Å; N108-D111 WeakPolarHBondContact ND2-CB 3.43Å; N108-D111 PolarHBondContact ND2-OD2 3.21Å; N108-D111 PolarHBondContact OD1-N 3.36Å; N108-D111 PolarHBondContact OD1-OD2 2.62Å; N108-D112 HydrophobicContact CB-CB 4.38Å; N108-D112 CarbonylContact O-C 3.41Å; N108-D112 WeakPolarHBondContact O-CA 3.49Å; N108-D112 PolarHBondContact O-N 2.71Å; N108-T115 PolarHBondContact N-OG1 3.42Å; N108-M239 PolarHBondContact ND2-O 3.21Å
109G85.9Confident92.1Very high22 Ų2230 Ų3023%0.22715%0.147CC..THydrogen-bonded Turntrans-62.2-25.1-177.200000115.4Q116G109-Q116 VanDerWaalsContact CA-OE1 3.23Å
110R86Confident91.9Very high181 Ų18129.6 Ų29.668%0.68315%0.145SC*.THydrogen-bonded Turntrans-72.7-51.4-178-179.3-171.9173.7169.83.9111.8N108N108-R110 PolarHBondContact O-N 3.27Å; N108-R110 PolarHBondContact OD1-N 3.11Å
111D88.8Confident91.8Very high41 Ų4129.7 Ų29.722%0.21915%0.146CC..THydrogen-bonded Turntrans-105.6-16.5-173.8-44.3-75.6000112.6N108 R238 R240N108-D111 WeakPolarHBondContact ND2-CB 3.43Å; N108-D111 PolarHBondContact ND2-OD2 3.21Å; N108-D111 PolarHBondContact OD1-N 3.36Å; N108-D111 PolarHBondContact OD1-OD2 2.62Å; D111-R238 HydrophobicContact CB-CB 4.45Å; D111-R238 WeakPolarHBondContact OD2-CB 3.33Å; D111-R238 WeakPolarHBondContact OD2-CG 3.36Å; D111-R240 HydrophobicContact CB-CG 4.38Å; D111-R240 WeakPolarHBondContact O-CD 3.32Å; D111-R240 WeakPolarHBondContact O-CG 3.47Å; D111-R240 PolarHBondContact O-NE 2.9Å
112D90.5Very high91.6Very high0 Ų030.4 Ų30.40%015%0.147CC..BIsolated β-bridgetrans-136.767.5176.3-160.88000112.7N108 L114 T115 R240 M241 M242N108-D112 HydrophobicContact CB-CB 4.38Å; N108-D112 CarbonylContact O-C 3.41Å; N108-D112 WeakPolarHBondContact O-CA 3.49Å; N108-D112 PolarHBondContact O-N 2.71Å; D112-L114 PolarHBondContact O-N 3.17Å; D112-T115 HydrophobicContact CB-CG2 4.07Å; D112-T115 WeakPolarHBondContact O-CB 3.39Å; D112-T115 PolarHBondContact O-N 3.38Å; D112-T115 PolarHBondContact O-OG1 3.17Å; D112-T115 WeakPolarHBondContact OD2-CG2 3.34Å; D112-R240 HydrophobicContact CB-CB 4.09Å; D112-R240 HydrophobicContact CB-CG 4.05Å; D112-M241 WeakPolarHBondContact OD2-CA 3.48Å; D112-M241 PolarHBondContact OD2-N 2.77Å; D112-M242 PolarHBondContact OD2-N 3.37Å
113P92.3Very high91.5Very high24 Ų2431 Ų3116%0.15616%0.159CC..G310 helixtrans-47.4-40.2-171.9-30.431.6000115.5T115 Q116 A302P113-T115 PolarHBondContact O-N 2.66Å; P113-Q116 WeakPolarHBondContact O-CB 3.16Å; P113-Q116 PolarHBondContact O-N 2.76Å; P113-A302 WeakPolarHBondContact O-CB 3.46Å
114L93.8Very high91.3Very high0 Ų035.6 Ų35.60%018%0.179CC..G310 helixtrans-60.4-21.5-177.7-63.8-170.3000113.4D112 Q116 H117 M242 H247 F250 M251 A301 F305D112-L114 PolarHBondContact O-N 3.17Å; L114-Q116 VanDerWaalsContact C-N 3.26Å; L114-Q116 PolarHBondContact O-N 2.91Å; L114-H117 PolarHBondContact O-CD2 3.36Å; L114-M242 HydrophobicContact CB-CG 4.11Å; L114-H247 HydrophobicContact CD1-CB 4.36Å; L114-F250 HydrophobicContact CD1-CB 3.98Å; L114-F250 HydrophobicContact CD1-CD2 4.42Å; L114-F250 HydrophobicContact CD2-CB 4.18Å; L114-M251 HydrophobicContact CD2-SD 4.24Å; L114-A301 HydrophobicContact CD2-CB 3.82Å; L114-F305 HydrophobicContact CB-CD1 4.23Å; L114-F305 HydrophobicContact CB-CG 4.37Å; L114-F305 HydrophobicContact CD1-CB 4.48Å; L114-F305 HydrophobicContact CD1-CD2 4.11Å; L114-F305 HydrophobicContact CD1-CG 4.2Å; L114-F305 HydrophobicContact CD2-CB 4.07Å
115T92.8Very high91.4Very high1 Ų140.2 Ų40.21%0.00620%0.196CC..G310 helixtrans-74.1-15.7176.264.30000113.4H107 N108 D112 P113 H117 N120 M241 M242H107-T115 WeakPolarHBondContact CB-O 3.46Å; N108-T115 PolarHBondContact N-OG1 3.42Å; D112-T115 HydrophobicContact CB-CG2 4.07Å; D112-T115 WeakPolarHBondContact O-CB 3.39Å; D112-T115 PolarHBondContact O-N 3.38Å; D112-T115 PolarHBondContact O-OG1 3.17Å; D112-T115 WeakPolarHBondContact OD2-CG2 3.34Å; P113-T115 PolarHBondContact O-N 2.66Å; T115-H117 PolarHBondContact O-N 2.64Å; T115-N120 WeakPolarHBondContact O-CB 3.47Å; T115-N120 PolarHBondContact O-ND2 2.79Å; T115-M241 HydrophobicContact CG2-CB 4.31Å; T115-M241 HydrophobicContact CG2-CE 4.04Å; T115-M242 HydrophobicContact CG2-CG 4.3Å
116Q92.5Very high91.8Very high20 Ų2039.1 Ų39.19%0.09319%0.19CC..  trans-83.447.1179.4-165172.7-42.100112.1G109 P113 L114 L121 E299 Q303G109-Q116 VanDerWaalsContact CA-OE1 3.23Å; P113-Q116 WeakPolarHBondContact O-CB 3.16Å; P113-Q116 PolarHBondContact O-N 2.76Å; L114-Q116 VanDerWaalsContact C-N 3.26Å; L114-Q116 PolarHBondContact O-N 2.91Å; Q116-L121 HydrophobicContact CG-CD2 3.51Å; Q116-L121 HydrophobicContact CG-CG 4.34Å; Q116-E299 PolarHBondContact NE2-OE1 3.33Å; Q116-Q303 PolarHBondContact O-NE2 3.02Å; Q116-Q303 VanDerWaalsContact O-NE2 3.12Å
117H93.9Very high92Very high16 Ų1643.2 Ų43.27%0.07421%0.207CC..SBendtrans-103.1160.6-179.463.249.8000112.8L114 T115 F119 N120 L121 A302 F305 V306L114-H117 PolarHBondContact O-CD2 3.36Å; T115-H117 PolarHBondContact O-N 2.64Å; H117-F119 PolarHBondContact ND1-N 2.97Å; H117-F119 PolarHBondContact O-N 3.45Å; H117-N120 PolarHBondContact CE1-ND2 2.96Å; H117-N120 PolarHBondContact ND1-N 3.22Å; H117-N120 PolarHBondContact NE2-ND2 3.48Å; H117-N120 PolarHBondContact O-N 2.99Å; H117-L121 WeakPolarHBondContact O-CG 3.33Å; H117-L121 PolarHBondContact O-N 3.12Å; H117-A302 HydrophobicContact CB-CB 4.04Å; H117-A302 VanDerWaalsContact CB-O 3.23Å; H117-A302 WeakPolarHBondContact CB-O 3.3Å; H117-F305 AromaticContact CD2-CD1 3.88Å; H117-V306 HydrophobicContact CB-CB 3.67Å; H117-V306 HydrophobicContact CB-CG1 3.76Å; H117-V306 HydrophobicContact CB-CG2 4.25Å
118L95.1Very high92.1Very high11 Ų1141 Ų416%0.05820%0.198CC..THydrogen-bonded Turntrans-45.5-37.2-175.7-178.268.1000114.5M129 R130 L133 F307 I452L118-M129 HydrophobicContact CB-CG 4.3Å; L118-M129 HydrophobicContact CD1-CB 4.03Å; L118-M129 HydrophobicContact CD1-CG 3.88Å; L118-R130 HydrophobicContact CD1-CB 3.92Å; L118-L133 HydrophobicContact CB-CD1 4.29Å; L118-L133 HydrophobicContact CD1-CD1 4.47Å; L118-L133 HydrophobicContact CD2-CD1 4Å; L118-L133 HydrophobicContact CG-CD1 4.48Å; L118-F307 HydrophobicContact CD2-CZ 4.42Å; L118-I452 HydrophobicContact CD2-CB 4.34Å; L118-I452 HydrophobicContact CD2-CD1 3.86Å; L118-I452 HydrophobicContact CD2-CG2 4.02Å
119F94.5Very high92.2Very high95 Ų9540.8 Ų40.842%0.41720%0.197SC..THydrogen-bonded Turntrans-66.4-36.8179.8-178-74.6000113.6R103 H117 V306R103-F119 PolarHBondContact NH1-O 3.04Å; H117-F119 PolarHBondContact ND1-N 2.97Å; H117-F119 PolarHBondContact O-N 3.45Å; F119-V306 HydrophobicContact CB-CG2 4.13Å
120N93.9Very high92.5Very high8 Ų841.5 Ų41.54%0.04319%0.192CC..THydrogen-bonded Turntrans-97.5-25.9-174.8-74.3-14.2000113.7Q105 F106 H107 T115 H117Q105-N120 HydrophobicContact CB-CB 4.33Å; F106-N120 PolarHBondContact O-ND2 2.81Å; H107-N120 HydrophobicContact CB-CB 4.19Å; H107-N120 PolarHBondContact CD2-O 3.27Å; T115-N120 WeakPolarHBondContact O-CB 3.47Å; T115-N120 PolarHBondContact O-ND2 2.79Å; H117-N120 PolarHBondContact CE1-ND2 2.96Å; H117-N120 PolarHBondContact ND1-N 3.22Å; H117-N120 PolarHBondContact NE2-ND2 3.48Å; H117-N120 PolarHBondContact O-N 2.99Å
121L94.5Very high92.7Very high3 Ų335.6 Ų35.62%0.01617%0.173CC..  trans-55.7148.3179.6-78.6175000111.4Q116 H117 K125 W126 M129 R449Q116-L121 HydrophobicContact CG-CD2 3.51Å; Q116-L121 HydrophobicContact CG-CG 4.34Å; H117-L121 WeakPolarHBondContact O-CG 3.33Å; H117-L121 PolarHBondContact O-N 3.12Å; L121-K125 HydrophobicContact CD2-CB 4Å; L121-K125 HydrophobicContact CD2-CD 4.23Å; L121-W126 HydrophobicContact CB-CB 3.97Å; L121-W126 WeakPolarHBondContact O-CB 3.32Å; L121-M129 HydrophobicContact CD1-CB 3.96Å; L121-M129 HydrophobicContact CD1-CE 4.45Å; L121-M129 HydrophobicContact CD1-CG 4.06Å; L121-R449 PolarHBondContact O-NH1 2.85Å; L121-R449 PolarHBondContact O-NH2 3.16Å
122D94.5Very high92.5Very high30 Ų3035.3 Ų35.316%0.1617%0.168CC..  trans-130.5169177.1-83.5-22.8000111.5D102 R103 G104 W126 R449D102-D122 VanDerWaalsContact CA-OD1 3.31Å; D102-D122 WeakPolarHBondContact CA-OD1 3.34Å; D102-D122 HydrophobicContact CB-CB 4.18Å; D102-D122 WeakPolarHBondContact CB-OD1 3.43Å; D102-D122 VanDerWaalsContact CG-CB 3.5Å; D102-D122 WeakPolarHBondContact OD1-CB 3.14Å; R103-D122 PolarHBondContact N-OD1 2.97Å; G104-D122 VanDerWaalsContact CA-OD2 3.25Å; G104-D122 WeakPolarHBondContact CA-OD2 3.34Å; G104-D122 PolarHBondContact N-OD2 2.99Å; D122-W126 PolarHBondContact O-N 3.41Å; D122-R449 IonicContact OD1-CZ 3.25Å; D122-R449 IonicContact OD1-NH1 3.77Å; D122-R449 PolarHBondContact OD1-NH1 3.07Å; D122-R449 IonicContact OD1-NH2 2.75Å; D122-R449 PolarHBondContact OD1-NH2 3.21Å
123G93.9Very high92.4Very high35 Ų3535.3 Ų35.336%0.36117%0.168SC..Hα-helixtrans56.8-141.5176.900000114.2D102 K125 W126 K127D102-G123 PolarHBondContact OD1-N 2.96Å; G123-K125 VanDerWaalsContact C-N 3.3Å; G123-K125 PolarHBondContact O-N 3.27Å; G123-W126 PolarHBondContact O-N 3.38Å; G123-K127 PolarHBondContact O-N 3.46Å; G123-K127 VanDerWaalsContact O-N 3.14Å
124K92.2Very high92.3Very high128 Ų12837.1 Ų37.156%0.55718%0.179SC*.Hα-helixtrans-58-40.5-178.5-170.6-177.8-173-57.60112.4W126 K127 D128K124-W126 VanDerWaalsContact C-N 3.32Å; K124-W126 PolarHBondContact O-N 3.18Å; K124-K127 PolarHBondContact O-N 3.2Å; K124-K127 VanDerWaalsContact O-N 3.16Å; K124-D128 IonicContact NZ-OD1 3.03Å; K124-D128 PolarHBondContact NZ-OD1 3.11Å; K124-D128 IonicContact NZ-OD2 3.94Å; K124-D128 PolarHBondContact NZ-OD2 3.03Å; K124-D128 WeakPolarHBondContact O-CB 3.35Å; K124-D128 PolarHBondContact O-N 3.38Å
125K91.3Very high91.9Very high112 Ų11240.7 Ų40.749%0.48720%0.202SC..Hα-helixtrans-59.8-42.4179.8-71.1-168171.7-161.30111.9L121 G123 M129L121-K125 HydrophobicContact CD2-CB 4Å; L121-K125 HydrophobicContact CD2-CD 4.23Å; G123-K125 VanDerWaalsContact C-N 3.3Å; G123-K125 PolarHBondContact O-N 3.27Å; K125-M129 VanDerWaalsContact O-CB 3.23Å; K125-M129 WeakPolarHBondContact O-CB 3.39Å; K125-M129 PolarHBondContact O-N 2.89Å
126W94.9Very high91.5Very high16 Ų1641.5 Ų41.56%0.06121%0.207CC..Hα-helixtrans-63.7-47.7174.3169.778000112F97 L121 D122 G123 K124 D128 M129 R130 R449F97-W126 AromaticContact CE1-CH2 3.9Å; F97-W126 HydrophobicContact CE1-CH2 3.9Å; F97-W126 AromaticContact CE1-CZ3 3.98Å; F97-W126 HydrophobicContact CE1-CZ3 3.98Å; F97-W126 AromaticContact CZ-CH2 3.44Å; F97-W126 HydrophobicContact CZ-CH2 3.44Å; F97-W126 VanDerWaalsContact CZ-CH2 3.44Å; F97-W126 HydrophobicContact CZ-CZ2 4.31Å; F97-W126 AromaticContact CZ-CZ3 3.74Å; F97-W126 HydrophobicContact CZ-CZ3 3.74Å; L121-W126 HydrophobicContact CB-CB 3.97Å; L121-W126 WeakPolarHBondContact O-CB 3.32Å; D122-W126 PolarHBondContact O-N 3.41Å; G123-W126 PolarHBondContact O-N 3.38Å; K124-W126 VanDerWaalsContact C-N 3.32Å; K124-W126 PolarHBondContact O-N 3.18Å; W126-D128 PolarHBondContact O-N 3.42Å; W126-M129 PolarHBondContact O-N 3.08Å; W126-R130 HydrophobicContact CZ2-CB 4.29Å; W126-R130 HydrophobicContact CZ2-CG 4.17Å; W126-R130 VanDerWaalsContact O-CB 3.3Å; W126-R130 WeakPolarHBondContact O-CB 3.41Å; W126-R130 PolarHBondContact O-N 2.84Å; W126-R449 VanDerWaalsContact CE2-CD 3.45Å; W126-R449 HydrophobicContact CH2-CB 4.09Å; W126-R449 HydrophobicContact CH2-CG 4.32Å; W126-R449 HydrophobicContact CZ2-CB 3.57Å; W126-R449 HydrophobicContact CZ2-CG 3.45Å; W126-R449 VanDerWaalsContact CZ2-CG 3.45Å
127K93.3Very high91.2Very high92 Ų9241.5 Ų41.540%0.421%0.207SC..Hα-helixtrans-57.8-50.9-179.8-174.6-171.1174.4-159.70110.9G123 K124 M129 R130 Q131 E290G123-K127 PolarHBondContact O-N 3.46Å; G123-K127 VanDerWaalsContact O-N 3.14Å; K124-K127 PolarHBondContact O-N 3.2Å; K124-K127 VanDerWaalsContact O-N 3.16Å; K127-M129 PolarHBondContact O-N 3.38Å; K127-R130 PolarHBondContact O-N 2.92Å; K127-Q131 WeakPolarHBondContact O-CG 3.2Å; K127-Q131 PolarHBondContact O-N 3.4Å; K127-E290 IonicContact NZ-OE1 2.72Å
128D90Very high91Very high17 Ų1743.4 Ų43.49%0.09122%0.22CC..Hα-helixtrans-59.6-48178.8-63.8-6.9000110.5K124 W126 R130 Q131 R132 I292K124-D128 IonicContact NZ-OD1 3.03Å; K124-D128 PolarHBondContact NZ-OD1 3.11Å; K124-D128 IonicContact NZ-OD2 3.94Å; K124-D128 PolarHBondContact NZ-OD2 3.03Å; K124-D128 WeakPolarHBondContact O-CB 3.35Å; K124-D128 PolarHBondContact O-N 3.38Å; W126-D128 PolarHBondContact O-N 3.42Å; D128-R130 PolarHBondContact O-N 3Å; D128-Q131 PolarHBondContact O-N 3.48Å; D128-R132 VanDerWaalsContact O-CG 3.28Å; D128-R132 WeakPolarHBondContact O-CG 3.42Å; D128-R132 PolarHBondContact O-N 3.39Å; D128-I292 HydrophobicContact CB-CD1 4.44Å; D128-I292 HydrophobicContact CB-CG2 4.4Å
129M90.8Very high90.7Very high5 Ų545.9 Ų45.93%0.02524%0.238CC..Hα-helixtrans-64-41.1179.9-17159.771.900111.7L118 L121 K125 W126 K127 Q131 R132 L133 M295 Q303L118-M129 HydrophobicContact CB-CG 4.3Å; L118-M129 HydrophobicContact CD1-CB 4.03Å; L118-M129 HydrophobicContact CD1-CG 3.88Å; L121-M129 HydrophobicContact CD1-CB 3.96Å; L121-M129 HydrophobicContact CD1-CE 4.45Å; L121-M129 HydrophobicContact CD1-CG 4.06Å; K125-M129 VanDerWaalsContact O-CB 3.23Å; K125-M129 WeakPolarHBondContact O-CB 3.39Å; K125-M129 PolarHBondContact O-N 2.89Å; W126-M129 PolarHBondContact O-N 3.08Å; K127-M129 PolarHBondContact O-N 3.38Å; M129-Q131 VanDerWaalsContact C-N 3.35Å; M129-Q131 PolarHBondContact O-N 3.01Å; M129-R132 PolarHBondContact O-N 3.23Å; M129-L133 HydrophobicContact CG-CD1 3.71Å; M129-L133 HydrophobicContact CG-CG 4.43Å; M129-L133 VanDerWaalsContact O-CG 3.25Å; M129-L133 WeakPolarHBondContact O-CG 3.47Å; M129-L133 PolarHBondContact O-N 3.15Å; M129-L133 VanDerWaalsContact O-N 3.12Å; M129-L133 HydrophobicContact SD-CD1 3.77Å; M129-L133 HydrophobicContact SD-CG 4.09Å; M129-M295 HydrophobicContact CE-CG 4.35Å; M129-M295 HydrophobicContact CE-SD 3.79Å; M129-M295 HydrophobicContact SD-SD 4.07Å; M129-Q303 HydrophobicContact CE-CG 4.3Å; M129-Q303 HydrophobicContact SD-CG 3.92Å
130R93.4Very high90.3Very high36 Ų3643.9 Ų43.914%0.13625%0.245CC..Hα-helixtrans-61.9-44.1176.9-177.459.1-178.8-134-2.8111.1L118 W126 K127 D128 L133 T134 N450L118-R130 HydrophobicContact CD1-CB 3.92Å; W126-R130 HydrophobicContact CZ2-CB 4.29Å; W126-R130 HydrophobicContact CZ2-CG 4.17Å; W126-R130 VanDerWaalsContact O-CB 3.3Å; W126-R130 WeakPolarHBondContact O-CB 3.41Å; W126-R130 PolarHBondContact O-N 2.84Å; K127-R130 PolarHBondContact O-N 2.92Å; D128-R130 PolarHBondContact O-N 3Å; R130-L133 PolarHBondContact O-N 3.39Å; R130-T134 WeakPolarHBondContact O-CB 3.36Å; R130-T134 PolarHBondContact O-N 2.84Å; R130-T134 PolarHBondContact O-OG1 3.02Å; R130-N450 PolarHBondContact NH1-O 3.12Å; R130-N450 PolarHBondContact NH2-O 3.34Å; R130-N450 PolarHBondContact NH2-OD1 3.05Å
131Q89.7Confident90Very high58 Ų5848.4 Ų48.427%0.27126%0.264SS..Hα-helixtrans-62.6-44.1177.1-74.5172.2-30.500111.5K127 D128 M129 L133 P135 L286K127-Q131 WeakPolarHBondContact O-CG 3.2Å; K127-Q131 PolarHBondContact O-N 3.4Å; D128-Q131 PolarHBondContact O-N 3.48Å; M129-Q131 VanDerWaalsContact C-N 3.35Å; M129-Q131 PolarHBondContact O-N 3.01Å; Q131-L133 VanDerWaalsContact C-N 3.31Å; Q131-L133 PolarHBondContact O-N 2.97Å; Q131-P135 VanDerWaalsContact O-CD 3.26Å; Q131-P135 WeakPolarHBondContact O-CD 3.19Å; Q131-L286 HydrophobicContact CB-CD1 4.38Å
132R84.6Confident89.8Confident34 Ų3448.4 Ų48.413%0.12826%0.264CS..Hα-helixtrans-59.7-38.5177.6-69.9176.5-146.6-158.40.3113.4D128 M129 L278 E293D128-R132 VanDerWaalsContact O-CG 3.28Å; D128-R132 WeakPolarHBondContact O-CG 3.42Å; D128-R132 PolarHBondContact O-N 3.39Å; M129-R132 PolarHBondContact O-N 3.23Å; R132-L278 HydrophobicContact CB-CD1 4.15Å; R132-E293 PolarHBondContact NH1-O 3.46Å; R132-E293 PolarHBondContact NH2-O 3.02Å
133L88.4Confident89.5Confident0 Ų052.3 Ų52.30%028%0.28CS..Hα-helixtrans-94.4-18.9-171-60.1171.4000113.8L118 M129 R130 Q131 P135 T136 F137 F271 L275 Q303 F307 I452L118-L133 HydrophobicContact CB-CD1 4.29Å; L118-L133 HydrophobicContact CD1-CD1 4.47Å; L118-L133 HydrophobicContact CD2-CD1 4Å; L118-L133 HydrophobicContact CG-CD1 4.48Å; M129-L133 HydrophobicContact CG-CD1 3.71Å; M129-L133 HydrophobicContact CG-CG 4.43Å; M129-L133 VanDerWaalsContact O-CG 3.25Å; M129-L133 WeakPolarHBondContact O-CG 3.47Å; M129-L133 PolarHBondContact O-N 3.15Å; M129-L133 VanDerWaalsContact O-N 3.12Å; M129-L133 HydrophobicContact SD-CD1 3.77Å; M129-L133 HydrophobicContact SD-CG 4.09Å; R130-L133 PolarHBondContact O-N 3.39Å; Q131-L133 VanDerWaalsContact C-N 3.31Å; Q131-L133 PolarHBondContact O-N 2.97Å; L133-P135 VanDerWaalsContact C-CD 3.47Å; L133-T136 WeakPolarHBondContact O-CB 3.36Å; L133-T136 PolarHBondContact O-N 3.45Å; L133-T136 PolarHBondContact O-OG1 3.37Å; L133-T136 VanDerWaalsContact O-OG1 3.12Å; L133-F137 WeakPolarHBondContact O-CD2 3.4Å; L133-F271 HydrophobicContact CD2-CE2 3.68Å; L133-F271 HydrophobicContact CD2-CZ 3.84Å; L133-L275 HydrophobicContact CD2-CD2 3.82Å; L133-Q303 HydrophobicContact CD1-CG 4.43Å; L133-F307 HydrophobicContact CD1-CE2 3.8Å; L133-F307 HydrophobicContact CD1-CZ 4.04Å; L133-I452 HydrophobicContact CB-CD1 3.72Å
134T89.8Confident89.2Confident63 Ų6356 Ų5639%0.38729%0.286SS..G310 helixtrans-57.8-40-179-66.30000113.6R130 T136 F137R130-T134 WeakPolarHBondContact O-CB 3.36Å; R130-T134 PolarHBondContact O-N 2.84Å; R130-T134 PolarHBondContact O-OG1 3.02Å; T134-T136 PolarHBondContact O-N 3.4Å; T134-T136 VanDerWaalsContact O-N 3.13Å; T134-F137 PolarHBondContact O-N 3.05Å
135P86Confident89Confident74 Ų7451.1 Ų51.148%0.48127%0.265SS..G310 helixtrans-57.6-26.7178.4-28.436.8000115Q131 L133 F137 T138Q131-P135 VanDerWaalsContact O-CD 3.26Å; Q131-P135 WeakPolarHBondContact O-CD 3.19Å; L133-P135 VanDerWaalsContact C-CD 3.47Å; P135-F137 VanDerWaalsContact C-N 3.27Å; P135-F137 PolarHBondContact O-N 3.18Å; P135-T138 WeakPolarHBondContact O-CG2 3.49Å; P135-T138 PolarHBondContact O-OG1 2.77Å; P135-T138 VanDerWaalsContact O-OG1 3.06Å
136T83.8Confident89Confident18 Ų1846.5 Ų46.511%0.1125%0.245CC..G310 helixtrans-63.5-32.3176.7-44.60000112.5L133 T134 K141 M142 F271 L274L133-T136 WeakPolarHBondContact O-CB 3.36Å; L133-T136 PolarHBondContact O-N 3.45Å; L133-T136 PolarHBondContact O-OG1 3.37Å; L133-T136 VanDerWaalsContact O-OG1 3.12Å; T134-T136 PolarHBondContact O-N 3.4Å; T134-T136 VanDerWaalsContact O-N 3.13Å; T136-K141 WeakPolarHBondContact O-CB 3.34Å; T136-M142 WeakPolarHBondContact O-CE 3.15Å; T136-F271 HydrophobicContact CG2-CB 4.47Å; T136-F271 HydrophobicContact CG2-CD2 3.57Å; T136-F271 HydrophobicContact CG2-CE2 4.26Å; T136-F271 HydrophobicContact CG2-CG 4.44Å; T136-L274 WeakPolarHBondContact OG1-CD2 3.5Å
137F87.4Confident88.8Confident20 Ų2049.8 Ų49.89%0.08827%0.268CS..G310 helixtrans-102.823.4-171-61.7-80.2000113L133 T134 P135 M142 F307 I452 R455 F456L133-F137 WeakPolarHBondContact O-CD2 3.4Å; T134-F137 PolarHBondContact O-N 3.05Å; P135-F137 VanDerWaalsContact C-N 3.27Å; P135-F137 PolarHBondContact O-N 3.18Å; F137-M142 HydrophobicContact CD1-CE 4.26Å; F137-F307 HydrophobicContact CE1-CE1 4.29Å; F137-F307 HydrophobicContact CE2-CD1 4.28Å; F137-F307 AromaticContact CE2-CE1 3.39Å; F137-F307 HydrophobicContact CE2-CE1 3.39Å; F137-F307 AromaticContact CE2-CZ 3.77Å; F137-F307 HydrophobicContact CE2-CZ 3.77Å; F137-F307 AromaticContact CZ-CD1 3.67Å; F137-F307 HydrophobicContact CZ-CD1 3.67Å; F137-F307 AromaticContact CZ-CE1 3.19Å; F137-F307 HydrophobicContact CZ-CE1 3.19Å; F137-F307 HydrophobicContact CZ-CZ 4.02Å; F137-I452 WeakPolarHBondContact CB-O 3.25Å; F137-I452 HydrophobicContact CD2-CD1 3.86Å; F137-I452 HydrophobicContact CD2-CG1 3.65Å; F137-I452 HydrophobicContact CD2-CG2 4.41Å; F137-I452 HydrophobicContact CE2-CD1 4.13Å; F137-I452 HydrophobicContact CE2-CG1 4.2Å; F137-I452 HydrophobicContact CE2-CG2 4.22Å; F137-I452 HydrophobicContact CG-CG1 4.3Å; F137-I452 WeakPolarHBondContact CG-O 3.31Å; F137-R455 PolarHBondContact O-NH1 3.43Å; F137-F456 HydrophobicContact CD1-CB 4.27Å; F137-F456 HydrophobicContact CE1-CB 4.32Å
138T88.9Confident88.7Confident57 Ų5747.6 Ų47.635%0.3526%0.263SS..SBendtrans-75155.3174.557.70000111.4P135 G140 K141 M142P135-T138 WeakPolarHBondContact O-CG2 3.49Å; P135-T138 PolarHBondContact O-OG1 2.77Å; P135-T138 VanDerWaalsContact O-OG1 3.06Å; T138-G140 PolarHBondContact O-N 3.28Å; T138-K141 PolarHBondContact O-N 3.01Å; T138-K141 VanDerWaalsContact O-N 3.09Å; T138-K141 WeakPolarHBondContact OG1-CG 3.07Å; T138-K141 PolarHBondContact OG1-N 2.88Å; T138-M142 WeakPolarHBondContact O-CG 3.32Å; T138-M142 PolarHBondContact O-N 3.26Å
139S87.9Confident88.8Confident62 Ų6246.8 Ų46.843%0.43426%0.258SS..Hα-helixtrans-57.7-36.9178.3-51.40000112.5M142 K143S139-M142 PolarHBondContact O-N 2.86Å; S139-K143 PolarHBondContact O-N 3.06Å
140G87.8Confident89Confident54 Ų5447.7 Ų47.756%0.55726%0.263SS*.Hα-helixtrans-62.8-42.1175.400000112.7T138 K143 F144T138-G140 PolarHBondContact O-N 3.28Å; G140-K143 PolarHBondContact O-N 2.9Å; G140-F144 WeakPolarHBondContact O-CB 3.45Å; G140-F144 PolarHBondContact O-N 3.07Å
141K86.4Confident89Confident103 Ų10352.5 Ų52.545%0.44829%0.285SS..Hα-helixtrans-69.4-33.5175-69.2-64.3-175.51800112.7T136 T138 F144 M145T136-K141 WeakPolarHBondContact O-CB 3.34Å; T138-K141 PolarHBondContact O-N 3.01Å; T138-K141 VanDerWaalsContact O-N 3.09Å; T138-K141 WeakPolarHBondContact OG1-CG 3.07Å; T138-K141 PolarHBondContact OG1-N 2.88Å; K141-F144 PolarHBondContact O-N 3.36Å; K141-M145 WeakPolarHBondContact O-CG 3.26Å; K141-M145 PolarHBondContact O-N 2.64Å
142M90.3Very high89.2Confident2 Ų250.4 Ų50.41%0.0128%0.276CS..Hα-helixtrans-62.8-49172.7-62.9-53.394.800110.9T136 F137 T138 S139 F144 M145 F146 Y353 R455 F456 M459T136-M142 WeakPolarHBondContact O-CE 3.15Å; F137-M142 HydrophobicContact CD1-CE 4.26Å; T138-M142 WeakPolarHBondContact O-CG 3.32Å; T138-M142 PolarHBondContact O-N 3.26Å; S139-M142 PolarHBondContact O-N 2.86Å; M142-F144 VanDerWaalsContact C-N 3.25Å; M142-F144 PolarHBondContact O-N 3.09Å; M142-M145 HydrophobicContact CE-CE 3.13Å; M142-M145 PolarHBondContact O-N 3.02Å; M142-M145 VanDerWaalsContact O-N 3.15Å; M142-M145 HydrophobicContact SD-CE 4.02Å; M142-F146 PolarHBondContact O-N 2.7Å; M142-Y353 HydrophobicContact CB-CE2 4.12Å; M142-R455 HydrophobicContact CG-CB 4.09Å; M142-R455 HydrophobicContact SD-CB 4.25Å; M142-F456 HydrophobicContact SD-CB 3.88Å; M142-F456 HydrophobicContact SD-CD2 4.22Å; M142-M459 HydrophobicContact CB-CE 4.49Å; M142-M459 HydrophobicContact CB-SD 4.22Å; M142-M459 HydrophobicContact SD-CE 4.09Å
143K89.1Confident89.7Confident113 Ų11348.8 Ų48.849%0.49127%0.27SS..Hα-helixtrans-59.9-37176.8-171.5166.2-175.71590112S139 G140 F146 Y353 E354S139-K143 PolarHBondContact O-N 3.06Å; G140-K143 PolarHBondContact O-N 2.9Å; K143-F146 VanDerWaalsContact O-CB 3.29Å; K143-F146 WeakPolarHBondContact O-CB 3.34Å; K143-F146 PolarHBondContact O-N 3.32Å; K143-Y353 HydrophobicContact CB-CD2 4.24Å; K143-Y353 HydrophobicContact CB-CE2 4.28Å; K143-Y353 HydrophobicContact CB-CG 4.44Å; K143-Y353 HydrophobicContact CD-CD1 4.38Å; K143-Y353 HydrophobicContact CG-CD2 4.45Å; K143-Y353 HydrophobicContact CG-CG 4.23Å; K143-E354 IonicContact NZ-OE1 2.83Å; K143-E354 PolarHBondContact NZ-OE1 2.76Å
144F86.6Confident90Very high113 Ų11353.4 Ų53.450%0.49629%0.292SS..Hα-helixtrans-66.2-39.9175.1-178.5-94.8000113.3G140 K141 M142 F146 P147 N269G140-F144 WeakPolarHBondContact O-CB 3.45Å; G140-F144 PolarHBondContact O-N 3.07Å; K141-F144 PolarHBondContact O-N 3.36Å; M142-F144 VanDerWaalsContact C-N 3.25Å; M142-F144 PolarHBondContact O-N 3.09Å; F144-F146 VanDerWaalsContact C-N 3.3Å; F144-P147 WeakPolarHBondContact O-CD 3.22Å; F144-N269 HydrophobicContact CE1-CB 3.62Å; F144-N269 HydrophobicContact CZ-CB 3.75Å
145M88.8Confident90.3Very high24 Ų2453 Ų5312%0.11829%0.285CS..Hα-helixtrans-75.9-19.1177.2-71.9-173.3-71.800113.3K141 M142 P147 T148 V149 C190 F456K141-M145 WeakPolarHBondContact O-CG 3.26Å; K141-M145 PolarHBondContact O-N 2.64Å; M142-M145 HydrophobicContact CE-CE 3.13Å; M142-M145 PolarHBondContact O-N 3.02Å; M142-M145 VanDerWaalsContact O-N 3.15Å; M142-M145 HydrophobicContact SD-CE 4.02Å; M145-P147 VanDerWaalsContact C-CD 3.48Å; M145-T148 WeakPolarHBondContact O-CB 3.31Å; M145-T148 PolarHBondContact O-N 3.43Å; M145-V149 PolarHBondContact O-N 3.06Å; M145-V149 VanDerWaalsContact O-N 3.17Å; M145-C190 HydrophobicContact SD-CB 4.23Å; M145-F456 HydrophobicContact CE-CD2 4.14Å; M145-F456 HydrophobicContact CE-CE2 4.48Å
146F90.8Very high90.8Very high15 Ų1549.5 Ų49.57%0.06626%0.263CS..Hα-helixtrans-50.7-43.8-172.6-170.1-92.8000114.7M142 K143 F144 T148 V149 I150 L351 T352 Y353 I356 M459 I463M142-F146 PolarHBondContact O-N 2.7Å; K143-F146 VanDerWaalsContact O-CB 3.29Å; K143-F146 WeakPolarHBondContact O-CB 3.34Å; K143-F146 PolarHBondContact O-N 3.32Å; F144-F146 VanDerWaalsContact C-N 3.3Å; F146-T148 VanDerWaalsContact C-N 3.28Å; F146-T148 PolarHBondContact O-N 3.47Å; F146-V149 WeakPolarHBondContact O-CB 3.47Å; F146-V149 PolarHBondContact O-N 3.2Å; F146-V149 VanDerWaalsContact O-N 3.13Å; F146-I150 HydrophobicContact CD1-CG1 3.82Å; F146-I150 HydrophobicContact CE1-CD1 3.79Å; F146-I150 HydrophobicContact CE1-CG1 3.4Å; F146-I150 VanDerWaalsContact CE1-CG1 3.4Å; F146-I150 HydrophobicContact CE2-CD1 4.41Å; F146-I150 HydrophobicContact CZ-CD1 3.69Å; F146-I150 HydrophobicContact CZ-CG1 3.84Å; F146-I150 WeakPolarHBondContact O-CG1 3.47Å; F146-I150 PolarHBondContact O-N 3.46Å; F146-L351 WeakPolarHBondContact CE1-O 3.48Å; F146-L351 WeakPolarHBondContact CZ-O 3.24Å; F146-T352 VanDerWaalsContact CE1-C 3.43Å; F146-T352 WeakPolarHBondContact CZ-O 3.48Å; F146-Y353 HydrophobicContact CB-CD2 4.27Å; F146-Y353 AromaticContact CD2-CD2 3.61Å; F146-Y353 HydrophobicContact CD2-CD2 3.61Å; F146-Y353 HydrophobicContact CD2-CG 4.37Å; F146-Y353 VanDerWaalsContact CE1-N 3.28Å; F146-Y353 HydrophobicContact CE2-CD2 4.14Å; F146-Y353 HydrophobicContact CG-CD2 4.05Å; F146-Y353 VanDerWaalsContact CZ-N 3.26Å; F146-I356 HydrophobicContact CE2-CG1 4.15Å; F146-I356 HydrophobicContact CZ-CG1 4.22Å; F146-M459 HydrophobicContact CD2-CG 4.44Å; F146-M459 HydrophobicContact CD2-SD 3.93Å; F146-I463 HydrophobicContact CD2-CD1 4.09Å; F146-I463 HydrophobicContact CE2-CD1 3.61Å; F146-I463 HydrophobicContact CE2-CG1 4.34Å; F146-I463 HydrophobicContact CZ-CD1 4.32Å
147P91.3Very high91.3Very high85 Ų8549.3 Ų49.355%0.55226%0.262SS*.Hα-helixtrans-61.4-34.6177-23.635.4000113.7F144 M145 I150 K151F144-P147 WeakPolarHBondContact O-CD 3.22Å; M145-P147 VanDerWaalsContact C-CD 3.48Å; P147-I150 PolarHBondContact O-N 3.4Å; P147-K151 PolarHBondContact O-N 3.36Å
148T90.6Very high91.7Very high46 Ų4653.4 Ų53.428%0.28228%0.279SS..Hα-helixtrans-68.4-41.4176.3-57.80000110.6M145 F146 K151 V152 T189M145-T148 WeakPolarHBondContact O-CB 3.31Å; M145-T148 PolarHBondContact O-N 3.43Å; F146-T148 VanDerWaalsContact C-N 3.28Å; F146-T148 PolarHBondContact O-N 3.47Å; T148-K151 PolarHBondContact O-N 2.96Å; T148-V152 WeakPolarHBondContact O-CG2 3.31Å; T148-V152 PolarHBondContact O-N 3.49Å; T148-V152 VanDerWaalsContact O-N 3.15Å; T148-T189 HydrophobicContact CG2-CG2 3.45Å; T148-T189 VanDerWaalsContact CG2-CG2 3.45Å
149V92.6Very high92Very high0 Ų050.8 Ų50.80%026%0.263CS..Hα-helixtrans-61.3-45.6175.81780000110.1M145 F146 K151 V152 S153 M186 C190 M459 I463M145-V149 PolarHBondContact O-N 3.06Å; M145-V149 VanDerWaalsContact O-N 3.17Å; F146-V149 WeakPolarHBondContact O-CB 3.47Å; F146-V149 PolarHBondContact O-N 3.2Å; F146-V149 VanDerWaalsContact O-N 3.13Å; V149-K151 PolarHBondContact O-N 3.49Å; V149-V152 PolarHBondContact O-N 2.99Å; V149-S153 WeakPolarHBondContact O-CB 3.45Å; V149-S153 PolarHBondContact O-N 3.3Å; V149-M186 HydrophobicContact CB-CE 4.27Å; V149-M186 HydrophobicContact CB-SD 4.06Å; V149-M186 HydrophobicContact CG1-CE 3.49Å; V149-M186 VanDerWaalsContact CG1-CE 3.49Å; V149-M186 HydrophobicContact CG1-SD 3.66Å; V149-M186 HydrophobicContact CG2-SD 4.24Å; V149-M186 WeakPolarHBondContact O-CE 3.48Å; V149-C190 VanDerWaalsContact CG2-SG 3.58Å; V149-M459 HydrophobicContact CG2-CE 3.9Å; V149-I463 HydrophobicContact CB-CD1 4.39Å; V149-I463 HydrophobicContact CG1-CD1 3.35Å
150I94.5Very high92.3Very high24 Ų2448 Ų4812%0.12324%0.243CC..Hα-helixtrans-60-46.3176.4-67.2-57.8000111.7F146 P147 V152 S153 E154 L351 I463F146-I150 HydrophobicContact CD1-CG1 3.82Å; F146-I150 HydrophobicContact CE1-CD1 3.79Å; F146-I150 HydrophobicContact CE1-CG1 3.4Å; F146-I150 VanDerWaalsContact CE1-CG1 3.4Å; F146-I150 HydrophobicContact CE2-CD1 4.41Å; F146-I150 HydrophobicContact CZ-CD1 3.69Å; F146-I150 HydrophobicContact CZ-CG1 3.84Å; F146-I150 WeakPolarHBondContact O-CG1 3.47Å; F146-I150 PolarHBondContact O-N 3.46Å; P147-I150 PolarHBondContact O-N 3.4Å; I150-V152 VanDerWaalsContact C-N 3.33Å; I150-V152 PolarHBondContact O-N 2.96Å; I150-S153 WeakPolarHBondContact CA-OG 3.41Å; I150-S153 CarbonylContact O-C 3.53Å; I150-S153 WeakPolarHBondContact O-CA 3.45Å; I150-S153 WeakPolarHBondContact O-CB 3.44Å; I150-S153 PolarHBondContact O-N 3.46Å; I150-S153 PolarHBondContact O-OG 3.05Å; I150-E154 HydrophobicContact CG2-CG 4.28Å; I150-E154 WeakPolarHBondContact O-CG 3.3Å; I150-E154 PolarHBondContact O-N 3.34Å; I150-L351 HydrophobicContact CD1-CB 3.8Å; I150-L351 WeakPolarHBondContact CD1-O 3.45Å; I150-I463 HydrophobicContact CD1-CD1 4.32Å; I150-I463 HydrophobicContact CD1-CG2 4.18Å
151K93.4Very high92.6Very high138 Ų13847.5 Ų47.560%0.623%0.23SC*.Hα-helixtrans-55.2-45.3177-174.3-175.9177.7-169.90112.6P147 T148 V149 S153 E154 E155P147-K151 PolarHBondContact O-N 3.36Å; T148-K151 PolarHBondContact O-N 2.96Å; V149-K151 PolarHBondContact O-N 3.49Å; K151-S153 VanDerWaalsContact C-N 3.3Å; K151-S153 PolarHBondContact O-N 2.68Å; K151-E154 PolarHBondContact O-N 3.32Å; K151-E155 PolarHBondContact O-N 2.89Å
152V94.6Very high92.9Very high13 Ų1348.2 Ų48.28%0.07924%0.235CC..Hα-helixtrans-65.5-37.1176.3176.90000110.8T148 V149 I150 E155 F156 F182 D185 M186 T189T148-V152 WeakPolarHBondContact O-CG2 3.31Å; T148-V152 PolarHBondContact O-N 3.49Å; T148-V152 VanDerWaalsContact O-N 3.15Å; V149-V152 PolarHBondContact O-N 2.99Å; I150-V152 VanDerWaalsContact C-N 3.33Å; I150-V152 PolarHBondContact O-N 2.96Å; V152-E155 PolarHBondContact O-N 2.96Å; V152-F156 WeakPolarHBondContact O-CB 3.41Å; V152-F156 PolarHBondContact O-N 3.02Å; V152-F182 HydrophobicContact CG1-CD2 4.28Å; V152-F182 HydrophobicContact CG1-CE2 4.29Å; V152-D185 HydrophobicContact CG1-CB 3.94Å; V152-M186 HydrophobicContact CB-CE 3.88Å; V152-M186 HydrophobicContact CB-CG 4.5Å; V152-M186 HydrophobicContact CB-SD 3.8Å; V152-M186 HydrophobicContact CG1-CE 3.96Å; V152-M186 HydrophobicContact CG1-CG 3.9Å; V152-M186 HydrophobicContact CG1-SD 3.87Å; V152-M186 HydrophobicContact CG2-SD 4.39Å; V152-T189 HydrophobicContact CG2-CG2 4.34Å
153S95.4Very high93Very high0 Ų052 Ų520%025%0.252CS..Hα-helixtrans-69.1-32.3178.184.40000114.2V149 I150 K151 F156 V157 Q467V149-S153 WeakPolarHBondContact O-CB 3.45Å; V149-S153 PolarHBondContact O-N 3.3Å; I150-S153 WeakPolarHBondContact CA-OG 3.41Å; I150-S153 CarbonylContact O-C 3.53Å; I150-S153 WeakPolarHBondContact O-CA 3.45Å; I150-S153 WeakPolarHBondContact O-CB 3.44Å; I150-S153 PolarHBondContact O-N 3.46Å; I150-S153 PolarHBondContact O-OG 3.05Å; K151-S153 VanDerWaalsContact C-N 3.3Å; K151-S153 PolarHBondContact O-N 2.68Å; S153-F156 WeakPolarHBondContact O-CB 3.41Å; S153-F156 PolarHBondContact O-N 3.1Å; S153-V157 WeakPolarHBondContact O-CG2 3.28Å; S153-V157 PolarHBondContact O-N 2.95Å; S153-Q467 PolarHBondContact OG-NE2 2.78Å
154E94.6Very high93.1Very high98 Ų9846.6 Ų46.646%0.45823%0.229SC..Hα-helixtrans-68.2-42.4173.4-70.3170.9170.800110.9I150 K151 F156 V157 K158I150-E154 HydrophobicContact CG2-CG 4.28Å; I150-E154 WeakPolarHBondContact O-CG 3.3Å; I150-E154 PolarHBondContact O-N 3.34Å; K151-E154 PolarHBondContact O-N 3.32Å; E154-F156 VanDerWaalsContact C-N 3.28Å; E154-F156 PolarHBondContact O-N 3.23Å; E154-V157 PolarHBondContact O-N 3.23Å; E154-K158 WeakPolarHBondContact O-CG 3.5Å; E154-K158 PolarHBondContact O-N 2.85Å
155E95.4Very high93Very high54 Ų5444.2 Ų44.225%0.25222%0.224SC..Hα-helixtrans-62.9-39.6175.2-168.758.7-159.400111.7K151 V152 K158 V159 R200K151-E155 PolarHBondContact O-N 2.89Å; V152-E155 PolarHBondContact O-N 2.96Å; E155-K158 WeakPolarHBondContact O-CB 3.08Å; E155-K158 PolarHBondContact O-N 3.46Å; E155-K158 IonicContact OE2-NZ 3.04Å; E155-V159 WeakPolarHBondContact O-CG2 3.47Å; E155-V159 PolarHBondContact O-N 2.89Å; E155-R200 IonicContact OE1-CZ 3.74Å; E155-R200 IonicContact OE1-NE 2.92Å; E155-R200 PolarHBondContact OE1-NE 2.97Å; E155-R200 IonicContact OE1-NH2 3.52Å; E155-R200 PolarHBondContact OE1-NH2 2.94Å
156F96Very high92.6Very high0 Ų047.3 Ų47.30%025%0.254CS..Hα-helixtrans-58.2-47.3173.1173.1-123.1000112.8V152 S153 E154 K158 V159 I160 L178 M179 F182 L199 I468V152-F156 WeakPolarHBondContact O-CB 3.41Å; V152-F156 PolarHBondContact O-N 3.02Å; S153-F156 WeakPolarHBondContact O-CB 3.41Å; S153-F156 PolarHBondContact O-N 3.1Å; E154-F156 VanDerWaalsContact C-N 3.28Å; E154-F156 PolarHBondContact O-N 3.23Å; F156-K158 VanDerWaalsContact C-N 3.34Å; F156-K158 PolarHBondContact O-N 3.09Å; F156-V159 PolarHBondContact O-N 3.49Å; F156-I160 HydrophobicContact CD1-CD1 4.36Å; F156-I160 HydrophobicContact CD2-CD1 4.11Å; F156-I160 HydrophobicContact CD2-CG1 4.38Å; F156-I160 HydrophobicContact CE1-CD1 3.8Å; F156-I160 HydrophobicContact CE2-CD1 3.53Å; F156-I160 HydrophobicContact CE2-CG1 4.05Å; F156-I160 HydrophobicContact CG-CD1 4.5Å; F156-I160 HydrophobicContact CZ-CD1 3.35Å; F156-I160 HydrophobicContact CZ-CG1 4.36Å; F156-I160 WeakPolarHBondContact O-CG1 3.48Å; F156-I160 PolarHBondContact O-N 2.75Å; F156-L178 HydrophobicContact CD2-CD1 4.42Å; F156-L178 HydrophobicContact CE2-CD1 3.82Å; F156-L178 HydrophobicContact CE2-CD2 4.32Å; F156-L178 HydrophobicContact CE2-CG 3.8Å; F156-L178 HydrophobicContact CZ-CG 4.47Å; F156-M179 HydrophobicContact CE2-CE 3.87Å; F156-M179 HydrophobicContact CZ-CE 3.4Å; F156-M179 HydrophobicContact CZ-SD 4.23Å; F156-F182 HydrophobicContact CB-CD2 3.61Å; F156-F182 HydrophobicContact CB-CE2 3.88Å; F156-F182 AromaticContact CD1-CD2 3.82Å; F156-F182 HydrophobicContact CD1-CD2 3.82Å; F156-F182 AromaticContact CD1-CE2 3.85Å; F156-F182 HydrophobicContact CD1-CE2 3.85Å; F156-F182 HydrophobicContact CD1-CG 4.18Å; F156-F182 HydrophobicContact CD1-CZ 4.28Å; F156-F182 HydrophobicContact CD2-CB 3.85Å; F156-F182 AromaticContact CD2-CD2 3.91Å; F156-F182 HydrophobicContact CD2-CD2 3.91Å; F156-F182 HydrophobicContact CD2-CG 4.03Å; F156-F182 HydrophobicContact CE1-CD1 4.5Å; F156-F182 HydrophobicContact CE1-CD2 4.44Å; F156-F182 HydrophobicContact CE1-CG 4.36Å; F156-F182 HydrophobicContact CE2-CB 3.88Å; F156-F182 HydrophobicContact CE2-CG 4.2Å; F156-F182 HydrophobicContact CG-CB 4.31Å; F156-F182 AromaticContact CG-CD2 3.51Å; F156-F182 HydrophobicContact CG-CD2 3.51Å; F156-F182 AromaticContact CG-CE2 3.92Å; F156-F182 HydrophobicContact CG-CE2 3.92Å; F156-F182 AromaticContact CG-CG 4Å; F156-F182 HydrophobicContact CG-CG 4Å; F156-F182 HydrophobicContact CZ-CB 4.4Å; F156-F182 HydrophobicContact CZ-CG 4.36Å; F156-L199 HydrophobicContact CB-CD1 3.98Å; F156-L199 HydrophobicContact CD2-CD2 3.69Å; F156-L199 HydrophobicContact CE2-CD2 4.43Å; F156-I468 HydrophobicContact CE1-CD1 3.86Å; F156-I468 HydrophobicContact CE1-CG1 3.77Å; F156-I468 HydrophobicContact CZ-CD1 3.8Å; F156-I468 HydrophobicContact CZ-CG1 4.06Å
157V95.3Very high91.7Very high15 Ų1549.6 Ų49.69%0.09128%0.276CS..Hα-helixtrans-61.9-41.5175.5170.80000111.5S153 E154 V159 I160 T161 Q467S153-V157 WeakPolarHBondContact O-CG2 3.28Å; S153-V157 PolarHBondContact O-N 2.95Å; E154-V157 PolarHBondContact O-N 3.23Å; V157-V159 PolarHBondContact O-N 3.42Å; V157-I160 PolarHBondContact O-N 2.87Å; V157-T161 VanDerWaalsContact O-CB 3.31Å; V157-T161 WeakPolarHBondContact O-CB 3.27Å; V157-T161 PolarHBondContact O-N 2.96Å; V157-T161 PolarHBondContact O-OG1 3.24Å; V157-Q467 HydrophobicContact CG2-CB 3.7Å; V157-Q467 HydrophobicContact CG2-CG 4.12Å
158K95.5Very high90.5Very high105 Ų10554.5 Ų54.546%0.45729%0.291SS..Hα-helixtrans-59.4-47176.7-69.9172.7-164.9166.70111.3E154 E155 F156 I160 T161 E162E154-K158 WeakPolarHBondContact O-CG 3.5Å; E154-K158 PolarHBondContact O-N 2.85Å; E155-K158 WeakPolarHBondContact O-CB 3.08Å; E155-K158 PolarHBondContact O-N 3.46Å; E155-K158 IonicContact OE2-NZ 3.04Å; F156-K158 VanDerWaalsContact C-N 3.34Å; F156-K158 PolarHBondContact O-N 3.09Å; K158-I160 PolarHBondContact O-N 3.5Å; K158-T161 WeakPolarHBondContact O-CB 3.43Å; K158-T161 PolarHBondContact O-N 3.43Å; K158-E162 VanDerWaalsContact O-CG 3.3Å; K158-E162 WeakPolarHBondContact O-CG 3.25Å; K158-E162 PolarHBondContact O-N 2.88Å
159V94.8Very high89.9Confident3 Ų357.5 Ų57.52%0.01831%0.306CS..Hα-helixtrans-62.6-42.1179.3170.20000111.9E155 F156 V157 T161 E162 Q163 L199 R200E155-V159 WeakPolarHBondContact O-CG2 3.47Å; E155-V159 PolarHBondContact O-N 2.89Å; F156-V159 PolarHBondContact O-N 3.49Å; V157-V159 PolarHBondContact O-N 3.42Å; V159-T161 VanDerWaalsContact C-N 3.35Å; V159-E162 PolarHBondContact O-N 3.24Å; V159-Q163 VanDerWaalsContact CG1-NE2 3.3Å; V159-Q163 WeakPolarHBondContact O-CG 3.28Å; V159-Q163 PolarHBondContact O-N 3.37Å; V159-Q163 VanDerWaalsContact O-N 3.15Å; V159-L199 HydrophobicContact CG2-CB 4.26Å; V159-R200 HydrophobicContact CG2-CG 4.01Å
160I95.3Very high89.7Confident3 Ų358.3 Ų58.32%0.01531%0.314CS..Hα-helixtrans-63.7-44.8174.4-64.3175.3000110.3F156 V157 K158 E162 Q163 V164 L173 L178 I468 F472 V503F156-I160 HydrophobicContact CD1-CD1 4.36Å; F156-I160 HydrophobicContact CD2-CD1 4.11Å; F156-I160 HydrophobicContact CD2-CG1 4.38Å; F156-I160 HydrophobicContact CE1-CD1 3.8Å; F156-I160 HydrophobicContact CE2-CD1 3.53Å; F156-I160 HydrophobicContact CE2-CG1 4.05Å; F156-I160 HydrophobicContact CG-CD1 4.5Å; F156-I160 HydrophobicContact CZ-CD1 3.35Å; F156-I160 HydrophobicContact CZ-CG1 4.36Å; F156-I160 WeakPolarHBondContact O-CG1 3.48Å; F156-I160 PolarHBondContact O-N 2.75Å; V157-I160 PolarHBondContact O-N 2.87Å; K158-I160 PolarHBondContact O-N 3.5Å; I160-E162 VanDerWaalsContact C-N 3.34Å; I160-E162 PolarHBondContact O-N 2.93Å; I160-Q163 PolarHBondContact O-N 3.15Å; I160-Q163 VanDerWaalsContact O-N 3.09Å; I160-V164 HydrophobicContact CG2-CG2 3.84Å; I160-V164 WeakPolarHBondContact O-CB 3.49Å; I160-V164 WeakPolarHBondContact O-CG2 3.47Å; I160-V164 PolarHBondContact O-N 3.31Å; I160-L173 HydrophobicContact CG2-CD1 4.37Å; I160-L178 HydrophobicContact CD1-CD2 3.98Å; I160-L178 HydrophobicContact CG1-CD1 4.23Å; I160-L178 HydrophobicContact CG1-CD2 3.89Å; I160-I468 HydrophobicContact CD1-CG1 4.08Å; I160-F472 HydrophobicContact CB-CE2 4.24Å; I160-F472 HydrophobicContact CB-CZ 4Å; I160-F472 HydrophobicContact CG2-CD1 4.16Å; I160-F472 HydrophobicContact CG2-CD2 4.24Å; I160-F472 HydrophobicContact CG2-CE1 3.64Å; I160-F472 HydrophobicContact CG2-CE2 3.75Å; I160-F472 HydrophobicContact CG2-CG 4.44Å; I160-F472 HydrophobicContact CG2-CZ 3.42Å; I160-F472 VanDerWaalsContact CG2-CZ 3.42Å; I160-V503 HydrophobicContact CG2-CG1 4.4Å
161T94.2Very high89.8Confident43 Ų4358 Ų5826%0.26431%0.314SS..Hα-helixtrans-57.3-49.6178.5-56.70000109.7V157 K158 V159 Q163 V164 R505V157-T161 VanDerWaalsContact O-CB 3.31Å; V157-T161 WeakPolarHBondContact O-CB 3.27Å; V157-T161 PolarHBondContact O-N 2.96Å; V157-T161 PolarHBondContact O-OG1 3.24Å; K158-T161 WeakPolarHBondContact O-CB 3.43Å; K158-T161 PolarHBondContact O-N 3.43Å; V159-T161 VanDerWaalsContact C-N 3.35Å; T161-Q163 PolarHBondContact O-N 3.5Å; T161-V164 PolarHBondContact O-N 3.4Å; T161-R505 PolarHBondContact O-NH2 3.05Å
162E92.9Very high89.9Confident119 Ų11954.4 Ų54.456%0.55630%0.304SS*.Hα-helixtrans-56.5-34.9176.6-70.9165.9-159.100113.1K158 V159 I160 R200K158-E162 VanDerWaalsContact O-CG 3.3Å; K158-E162 WeakPolarHBondContact O-CG 3.25Å; K158-E162 PolarHBondContact O-N 2.88Å; V159-E162 PolarHBondContact O-N 3.24Å; I160-E162 VanDerWaalsContact C-N 3.34Å; I160-E162 PolarHBondContact O-N 2.93Å; E162-R200 IonicContact OE1-CZ 2.77Å; E162-R200 IonicContact OE1-NH1 3.34Å; E162-R200 PolarHBondContact OE1-NH1 3.35Å; E162-R200 IonicContact OE1-NH2 3.37Å; E162-R200 PolarHBondContact OE1-NH2 2.9Å; E162-R200 IonicContact OE2-CZ 3.25Å; E162-R200 IonicContact OE2-NH1 2.81Å; E162-R200 PolarHBondContact OE2-NH1 3.3Å; E162-R200 IonicContact OE2-NH2 2.78Å
163Q91.2Very high90Very high80 Ų8054.5 Ų54.537%0.37430%0.304SS..Hα-helixtrans-84-27.5-179.8-69.4177.129.700114.3V159 I160 T161 P165 L173V159-Q163 VanDerWaalsContact CG1-NE2 3.3Å; V159-Q163 WeakPolarHBondContact O-CG 3.28Å; V159-Q163 PolarHBondContact O-N 3.37Å; V159-Q163 VanDerWaalsContact O-N 3.15Å; I160-Q163 PolarHBondContact O-N 3.15Å; I160-Q163 VanDerWaalsContact O-N 3.09Å; T161-Q163 PolarHBondContact O-N 3.5Å; Q163-P165 WeakPolarHBondContact O-CD 3.49Å; Q163-L173 HydrophobicContact CB-CD2 4.19Å
164V92.2Very high90Very high0 Ų057.5 Ų57.50%032%0.318CS..SBendtrans-99.4106.7-177.9-178.90000108.7I160 T161 A171 L173 F472 V503 R505I160-V164 HydrophobicContact CG2-CG2 3.84Å; I160-V164 WeakPolarHBondContact O-CB 3.49Å; I160-V164 WeakPolarHBondContact O-CG2 3.47Å; I160-V164 PolarHBondContact O-N 3.31Å; T161-V164 PolarHBondContact O-N 3.4Å; V164-A171 HydrophobicContact CG2-CB 4.31Å; V164-L173 HydrophobicContact CG2-CD1 3.87Å; V164-F472 HydrophobicContact CB-CE1 4.3Å; V164-F472 HydrophobicContact CG2-CE1 4.41Å; V164-V503 WeakPolarHBondContact CG1-O 3.26Å; V164-V503 HydrophobicContact CG2-CB 4.02Å; V164-V503 HydrophobicContact CG2-CG1 3.9Å; V164-R505 HydrophobicContact CG1-CG 3.97Å; V164-R505 PolarHBondContact O-NE 3.49Å; V164-R505 PolarHBondContact O-NH2 3.17Å
165P84.7Confident90.1Very high63 Ų6353 Ų5341%0.40930%0.297SS..  trans-66153.1179.128.1-33000111.2Q163 A167Q163-P165 WeakPolarHBondContact O-CD 3.49Å; P165-A167 HydrophobicContact CB-CB 4.26Å; P165-A167 HydrophobicContact CG-CB 4.44Å; P165-A167 PolarHBondContact O-N 3.42Å
166A78.9Confident90Very high90 Ų9052 Ų5274%0.74429%0.292SS*.SBendtrans-77.634.417200000112.5
167A73.2Confident89.9Confident63 Ų6353 Ų5352%0.52130%0.297SS..SBendtrans-101.4160.4-178.700000110.7P165 N169 G170P165-A167 HydrophobicContact CB-CB 4.26Å; P165-A167 HydrophobicContact CG-CB 4.44Å; P165-A167 PolarHBondContact O-N 3.42Å; A167-N169 PolarHBondContact O-N 2.95Å; A167-G170 PolarHBondContact O-N 2.68Å
168Q66.1Low89.9Confident188 Ų18852.8 Ų52.888%0.87930%0.295SS*.THydrogen-bonded Turntrans-57.4127.2170.1-81.2176.9-16.900109.2
169N77.3Confident89.9Confident109 Ų10947.8 Ų47.858%0.58327%0.273SS*.THydrogen-bonded Turntrans902.2177.7-45.3-32000117.8A167 R502 E504A167-N169 PolarHBondContact O-N 2.95Å; N169-R502 WeakPolarHBondContact O-CD 3.3Å; N169-R502 PolarHBondContact O-NH1 3.47Å; N169-E504 WeakPolarHBondContact CA-OE1 3.09Å
170G89Confident89.9Confident16 Ų1647.7 Ų47.717%0.16527%0.273CS..  trans58-145.7171.500000114.8A167 V503A167-G170 PolarHBondContact O-N 2.68Å; G170-V503 CarbonylContact C-O 3.03Å; G170-V503 VanDerWaalsContact CA-O 3.29Å; G170-V503 WeakPolarHBondContact CA-O 3.28Å
171A94.9Very high89.8Confident17 Ų1749.6 Ų49.614%0.1428%0.28CS..EExtended strand (participates in β ladder)trans-134.1149.5177.100000112.3V164 L173 R502 V503V164-A171 HydrophobicContact CG2-CB 4.31Å; A171-L173 HydrophobicContact CB-CD2 4.2Å; A171-R502 WeakPolarHBondContact O-CA 3.35Å; A171-V503 PolarHBondContact N-O 2.8Å; A171-V503 PolarHBondContact O-N 3.08Å
172V96.1Very high89.8Confident63 Ų6347.6 Ų47.638%0.38227%0.267SS..EExtended strand (participates in β ladder)trans-86.7120.4169.6177.20000108.4C477 Y500 L501V172-C477 HydrophobicContact CG2-CB 4Å; V172-Y500 HydrophobicContact CG1-CD1 4.42Å; V172-L501 WeakPolarHBondContact CA-O 3.32Å
173L96.3Very high89.9Confident15 Ų1541.9 Ų41.98%0.07924%0.241CC..EExtended strand (participates in β ladder)trans-118.2144.4-179.3-57.4-174.7000110.7I160 Q163 V164 A171 I175 L178 Y500 L501 V503I160-L173 HydrophobicContact CG2-CD1 4.37Å; Q163-L173 HydrophobicContact CB-CD2 4.19Å; V164-L173 HydrophobicContact CG2-CD1 3.87Å; A171-L173 HydrophobicContact CB-CD2 4.2Å; L173-I175 HydrophobicContact CB-CD1 4.07Å; L173-I175 PolarHBondContact O-N 3.08Å; L173-L178 HydrophobicContact CD1-CD2 4.09Å; L173-Y500 WeakPolarHBondContact O-CA 3.35Å; L173-L501 PolarHBondContact N-O 2.86Å; L173-L501 PolarHBondContact O-N 2.82Å; L173-L501 VanDerWaalsContact O-N 3.1Å; L173-V503 HydrophobicContact CB-CG2 4.35Å; L173-V503 HydrophobicContact CD1-CB 4.19Å; L173-V503 HydrophobicContact CD1-CG2 3.95Å; L173-V503 HydrophobicContact CG-CB 4.49Å; L173-V503 HydrophobicContact CG-CG2 4.18Å
174E96.4Very high90Very high64 Ų6438.1 Ų38.130%0.29922%0.223SC..EExtended strand (participates in β ladder)trans-78.795.1166-165.2-153.7159.400109.4K176 E177 L178 G498 I499 Y500E174-K176 VanDerWaalsContact C-N 3.35Å; E174-K176 PolarHBondContact O-N 2.75Å; E174-E177 HydrophobicContact CB-CB 4.44Å; E174-E177 HydrophobicContact CG-CB 4.17Å; E174-E177 PolarHBondContact O-N 2.72Å; E174-E177 WeakPolarHBondContact OE1-CB 3.25Å; E174-E177 WeakPolarHBondContact OE2-CB 3.31Å; E174-L178 WeakPolarHBondContact O-CB 3.14Å; E174-L178 PolarHBondContact O-N 3.43Å; E174-L178 VanDerWaalsContact O-N 3.1Å; E174-G498 WeakPolarHBondContact OE1-CA 3.33Å; E174-I499 CarbonylContact C-O 3.57Å; E174-Y500 HydrophobicContact CB-CD1 3.98Å; E174-Y500 HydrophobicContact CB-CE1 3.62Å; E174-Y500 HydrophobicContact CG-CD1 4.28Å; E174-Y500 HydrophobicContact CG-CE1 3.82Å; E174-Y500 HydrophobicContact CG-CE2 4.28Å
175I96.6Very high90Very high4 Ų438.6 Ų38.62%0.02123%0.226CC..Hα-helixtrans-63.5-39.9-172.8-60.3-58.6000112L173 E177 L178 M179 L323 I499 L501 V503L173-I175 HydrophobicContact CB-CD1 4.07Å; L173-I175 PolarHBondContact O-N 3.08Å; I175-E177 PolarHBondContact O-N 3.28Å; I175-L178 PolarHBondContact O-N 3.36Å; I175-M179 HydrophobicContact CG2-CE 4.44Å; I175-M179 HydrophobicContact CG2-CG 4.08Å; I175-M179 WeakPolarHBondContact O-CB 3.42Å; I175-M179 VanDerWaalsContact O-CG 3.3Å; I175-M179 WeakPolarHBondContact O-CG 3.39Å; I175-M179 PolarHBondContact O-N 2.87Å; I175-L323 HydrophobicContact CG2-CB 4.18Å; I175-L323 HydrophobicContact CG2-CD1 3.48Å; I175-L323 VanDerWaalsContact CG2-CD1 3.48Å; I175-L323 HydrophobicContact CG2-CG 4.48Å; I175-I499 WeakPolarHBondContact CB-O 3.38Å; I175-I499 PolarHBondContact N-O 3.03Å; I175-L501 HydrophobicContact CD1-CB 4.34Å; I175-L501 HydrophobicContact CG1-CB 3.77Å; I175-L501 HydrophobicContact CG1-CD1 3.88Å; I175-L501 HydrophobicContact CG1-CG 3.89Å; I175-V503 HydrophobicContact CD1-CG2 3.9Å
176K94.1Very high90.4Very high33 Ų3335.6 Ų35.614%0.14321%0.206CC..Hα-helixtrans-59.3-48-179.6-176.8176179.3-171.70112.3E174 M179 A180 S320 T495E174-K176 VanDerWaalsContact C-N 3.35Å; E174-K176 PolarHBondContact O-N 2.75Å; K176-M179 PolarHBondContact O-N 3.46Å; K176-A180 WeakPolarHBondContact O-CB 3.25Å; K176-A180 PolarHBondContact O-N 2.75Å; K176-S320 WeakPolarHBondContact CA-OG 3.5Å; K176-T495 WeakPolarHBondContact CD-OG1 3.49Å; K176-T495 PolarHBondContact NZ-OG1 3.05Å
177E93.3Very high90.9Very high21 Ų2131.7 Ų31.710%0.09817%0.173CC..Hα-helixtrans-68.8-39.7179176.556.6-157.700111.9E174 I175 M179 A180 R181 R207E174-E177 HydrophobicContact CB-CB 4.44Å; E174-E177 HydrophobicContact CG-CB 4.17Å; E174-E177 PolarHBondContact O-N 2.72Å; E174-E177 WeakPolarHBondContact OE1-CB 3.25Å; E174-E177 WeakPolarHBondContact OE2-CB 3.31Å; I175-E177 PolarHBondContact O-N 3.28Å; E177-M179 PolarHBondContact O-N 3.06Å; E177-A180 PolarHBondContact O-N 3.2Å; E177-R181 WeakPolarHBondContact O-CG 3.32Å; E177-R181 PolarHBondContact O-N 3.05Å; E177-R181 IonicContact OE1-CZ 3.56Å; E177-R181 IonicContact OE1-NE 3.52Å; E177-R181 PolarHBondContact OE1-NE 2.95Å; E177-R181 IonicContact OE1-NH2 2.74Å; E177-R207 IonicContact OE1-NE 3.62Å; E177-R207 IonicContact OE2-CZ 3.94Å; E177-R207 IonicContact OE2-NE 3.58Å; E177-R207 PolarHBondContact OE2-NE 3.19Å; E177-R207 IonicContact OE2-NH2 3.5Å; E177-R207 PolarHBondContact OE2-NH2 2.73Å
178L95.2Very high91.7Very high9 Ų928.7 Ų28.75%0.04715%0.148CC..Hα-helixtrans-59.7-45.8174.117963.4000112.1F156 I160 L173 E174 I175 A180 R181 F182F156-L178 HydrophobicContact CD2-CD1 4.42Å; F156-L178 HydrophobicContact CE2-CD1 3.82Å; F156-L178 HydrophobicContact CE2-CD2 4.32Å; F156-L178 HydrophobicContact CE2-CG 3.8Å; F156-L178 HydrophobicContact CZ-CG 4.47Å; I160-L178 HydrophobicContact CD1-CD2 3.98Å; I160-L178 HydrophobicContact CG1-CD1 4.23Å; I160-L178 HydrophobicContact CG1-CD2 3.89Å; L173-L178 HydrophobicContact CD1-CD2 4.09Å; E174-L178 WeakPolarHBondContact O-CB 3.14Å; E174-L178 PolarHBondContact O-N 3.43Å; E174-L178 VanDerWaalsContact O-N 3.1Å; I175-L178 PolarHBondContact O-N 3.36Å; L178-A180 VanDerWaalsContact C-N 3.33Å; L178-R181 PolarHBondContact O-N 3.02Å; L178-F182 PolarHBondContact O-N 2.9Å; L178-F182 VanDerWaalsContact O-N 3.07Å
179M96.3Very high92.8Very high0 Ų020.5 Ų20.50%011%0.111CC..Hα-helixtrans-66.4-35.9175.5-67.2-45.890.100111.8F156 I175 K176 E177 F182 T183 S316 M319 S320 L323 I468F156-M179 HydrophobicContact CE2-CE 3.87Å; F156-M179 HydrophobicContact CZ-CE 3.4Å; F156-M179 HydrophobicContact CZ-SD 4.23Å; I175-M179 HydrophobicContact CG2-CE 4.44Å; I175-M179 HydrophobicContact CG2-CG 4.08Å; I175-M179 WeakPolarHBondContact O-CB 3.42Å; I175-M179 VanDerWaalsContact O-CG 3.3Å; I175-M179 WeakPolarHBondContact O-CG 3.39Å; I175-M179 PolarHBondContact O-N 2.87Å; K176-M179 PolarHBondContact O-N 3.46Å; E177-M179 PolarHBondContact O-N 3.06Å; M179-F182 PolarHBondContact O-N 3.35Å; M179-T183 WeakPolarHBondContact O-CG2 3.49Å; M179-T183 PolarHBondContact O-N 3.44Å; M179-T183 PolarHBondContact O-OG1 2.88Å; M179-S316 VanDerWaalsContact C-CB 3.46Å; M179-S316 WeakPolarHBondContact O-CB 3.32Å; M179-M319 HydrophobicContact CB-CE 4.46Å; M179-M319 HydrophobicContact CG-CB 3.84Å; M179-M319 HydrophobicContact SD-CB 3.79Å; M179-M319 HydrophobicContact SD-CE 4.27Å; M179-M319 HydrophobicContact SD-SD 4.2Å; M179-S320 WeakPolarHBondContact CG-OG 3.01Å; M179-L323 HydrophobicContact CE-CD1 4.36Å; M179-L323 HydrophobicContact SD-CD1 4.04Å; M179-I468 HydrophobicContact CE-CD1 3.87Å; M179-I468 HydrophobicContact SD-CD1 4.04Å
180A93.1Very high93.1Very high1 Ų115.6 Ų15.61%0.0089%0.085CC..Hα-helixtrans-65.2-41.5177.500000111.7K176 E177 L178 T183 T184 R207K176-A180 WeakPolarHBondContact O-CB 3.25Å; K176-A180 PolarHBondContact O-N 2.75Å; E177-A180 PolarHBondContact O-N 3.2Å; L178-A180 VanDerWaalsContact C-N 3.33Å; A180-T183 PolarHBondContact O-OG1 3.22Å; A180-T184 VanDerWaalsContact O-CB 3.31Å; A180-T184 WeakPolarHBondContact O-CB 3.44Å; A180-T184 PolarHBondContact O-N 3.49Å; A180-T184 PolarHBondContact O-OG1 3.13Å; A180-R207 VanDerWaalsContact CB-CZ 3.45Å; A180-R207 VanDerWaalsContact CB-NH2 3.34Å
181R93.8Very high92.8Very high44 Ų4415.2 Ų15.217%0.1668%0.08CC..Hα-helixtrans-63.5-47.2173.4-65.6169.7-159.8172.611.1111.7E177 L178 T183 T184 D185 T198 L199E177-R181 WeakPolarHBondContact O-CG 3.32Å; E177-R181 PolarHBondContact O-N 3.05Å; E177-R181 IonicContact OE1-CZ 3.56Å; E177-R181 IonicContact OE1-NE 3.52Å; E177-R181 PolarHBondContact OE1-NE 2.95Å; E177-R181 IonicContact OE1-NH2 2.74Å; L178-R181 PolarHBondContact O-N 3.02Å; R181-T183 PolarHBondContact O-N 3.44Å; R181-T184 WeakPolarHBondContact O-CB 3.42Å; R181-T184 PolarHBondContact O-N 3.41Å; R181-D185 PolarHBondContact O-N 3Å; R181-T198 WeakPolarHBondContact CA-OG1 3.26Å; R181-T198 WeakPolarHBondContact CD-O 3.42Å; R181-T198 PolarHBondContact O-OG1 3.46Å; R181-L199 HydrophobicContact CB-CD2 4.01Å; R181-L199 HydrophobicContact CB-CG 4.5Å
182F95.3Very high92.1Very high0 Ų014.4 Ų14.40%07%0.074CC..Hα-helixtrans-55.5-50.3176.7171.8-120.5000112.6V152 F156 L178 M179 T184 D185 M186 L199 M319V152-F182 HydrophobicContact CG1-CD2 4.28Å; V152-F182 HydrophobicContact CG1-CE2 4.29Å; F156-F182 HydrophobicContact CB-CD2 3.61Å; F156-F182 HydrophobicContact CB-CE2 3.88Å; F156-F182 AromaticContact CD1-CD2 3.82Å; F156-F182 HydrophobicContact CD1-CD2 3.82Å; F156-F182 AromaticContact CD1-CE2 3.85Å; F156-F182 HydrophobicContact CD1-CE2 3.85Å; F156-F182 HydrophobicContact CD1-CG 4.18Å; F156-F182 HydrophobicContact CD1-CZ 4.28Å; F156-F182 HydrophobicContact CD2-CB 3.85Å; F156-F182 AromaticContact CD2-CD2 3.91Å; F156-F182 HydrophobicContact CD2-CD2 3.91Å; F156-F182 HydrophobicContact CD2-CG 4.03Å; F156-F182 HydrophobicContact CE1-CD1 4.5Å; F156-F182 HydrophobicContact CE1-CD2 4.44Å; F156-F182 HydrophobicContact CE1-CG 4.36Å; F156-F182 HydrophobicContact CE2-CB 3.88Å; F156-F182 HydrophobicContact CE2-CG 4.2Å; F156-F182 HydrophobicContact CG-CB 4.31Å; F156-F182 AromaticContact CG-CD2 3.51Å; F156-F182 HydrophobicContact CG-CD2 3.51Å; F156-F182 AromaticContact CG-CE2 3.92Å; F156-F182 HydrophobicContact CG-CE2 3.92Å; F156-F182 AromaticContact CG-CG 4Å; F156-F182 HydrophobicContact CG-CG 4Å; F156-F182 HydrophobicContact CZ-CB 4.4Å; F156-F182 HydrophobicContact CZ-CG 4.36Å; L178-F182 PolarHBondContact O-N 2.9Å; L178-F182 VanDerWaalsContact O-N 3.07Å; M179-F182 PolarHBondContact O-N 3.35Å; F182-T184 PolarHBondContact O-N 2.87Å; F182-D185 PolarHBondContact O-N 3.37Å; F182-M186 HydrophobicContact CD2-CE 4.25Å; F182-M186 HydrophobicContact CD2-CG 4.32Å; F182-M186 HydrophobicContact CE1-CE 4.29Å; F182-M186 HydrophobicContact CE2-CE 3.2Å; F182-M186 HydrophobicContact CE2-CG 4.04Å; F182-M186 HydrophobicContact CE2-SD 4.48Å; F182-M186 HydrophobicContact CZ-CE 3.24Å; F182-M186 HydrophobicContact CZ-CG 4.17Å; F182-M186 VanDerWaalsContact O-CG 3.3Å; F182-M186 WeakPolarHBondContact O-CG 3.37Å; F182-M186 PolarHBondContact O-N 2.76Å; F182-L199 HydrophobicContact CB-CD2 4.13Å; F182-M319 HydrophobicContact CD1-CE 3.65Å; F182-M319 HydrophobicContact CD1-SD 4.19Å; F182-M319 HydrophobicContact CE1-CE 3.87Å; F182-M319 HydrophobicContact CE1-SD 3.97Å
183T94.6Very high91.4Very high0 Ų012.2 Ų12.20%06%0.064CC..Hα-helixtrans-70.8-29.3179.454.60000113.4M179 A180 R181 M186 I187 F312 S316 M319M179-T183 WeakPolarHBondContact O-CG2 3.49Å; M179-T183 PolarHBondContact O-N 3.44Å; M179-T183 PolarHBondContact O-OG1 2.88Å; A180-T183 PolarHBondContact O-OG1 3.22Å; R181-T183 PolarHBondContact O-N 3.44Å; T183-M186 PolarHBondContact O-N 3Å; T183-I187 WeakPolarHBondContact O-CG2 3.24Å; T183-I187 PolarHBondContact O-N 3.18Å; T183-F312 PolarHBondContact OG1-O 3.05Å; T183-F312 VanDerWaalsContact OG1-O 3.06Å; T183-S316 WeakPolarHBondContact OG1-CB 3.43Å; T183-M319 HydrophobicContact CG2-CE 3.28Å
184T93.1Very high90.7Very high0 Ų013.2 Ų13.20%07%0.069CC..Hα-helixtrans-62.6-47.5171.3-61.20000111A180 R181 F182 M186 I187 G188 C196 T198 F206 Y308A180-T184 VanDerWaalsContact O-CB 3.31Å; A180-T184 WeakPolarHBondContact O-CB 3.44Å; A180-T184 PolarHBondContact O-N 3.49Å; A180-T184 PolarHBondContact O-OG1 3.13Å; R181-T184 WeakPolarHBondContact O-CB 3.42Å; R181-T184 PolarHBondContact O-N 3.41Å; F182-T184 PolarHBondContact O-N 2.87Å; T184-M186 VanDerWaalsContact C-N 3.34Å; T184-M186 PolarHBondContact O-N 3.49Å; T184-I187 WeakPolarHBondContact O-CG2 3.47Å; T184-I187 PolarHBondContact O-N 2.89Å; T184-G188 PolarHBondContact O-N 3.44Å; T184-C196 HydrophobicContact CG2-CB 4.45Å; T184-T198 HydrophobicContact CG2-CG2 3.68Å; T184-F206 HydrophobicContact CG2-CB 4.39Å; T184-Y308 HydrophobicContact CG2-CE2 4.1Å
185D92.9Very high90Very high10 Ų1015.8 Ų15.85%0.0538%0.081CC..Hα-helixtrans-67.8-35.5178.2-74.31000111.6V152 R181 F182 T189 C196 N197 T198 L199V152-D185 HydrophobicContact CG1-CB 3.94Å; R181-D185 PolarHBondContact O-N 3Å; F182-D185 PolarHBondContact O-N 3.37Å; D185-T189 VanDerWaalsContact O-CB 3.25Å; D185-T189 WeakPolarHBondContact O-CB 3.33Å; D185-T189 PolarHBondContact O-N 3.13Å; D185-T189 PolarHBondContact O-OG1 3.04Å; D185-C196 WeakPolarHBondContact OD1-CB 3.17Å; D185-N197 PolarHBondContact OD1-N 3.1Å; D185-T198 VanDerWaalsContact CG-OG1 3.27Å; D185-T198 WeakPolarHBondContact OD1-CB 3.32Å; D185-T198 WeakPolarHBondContact OD1-CG2 3.35Å; D185-T198 PolarHBondContact OD1-N 3.45Å; D185-T198 PolarHBondContact OD1-OG1 2.95Å; D185-T198 PolarHBondContact OD2-N 3.06Å; D185-T198 VanDerWaalsContact OD2-N 3.1Å; D185-L199 HydrophobicContact CB-CD1 4.49Å; D185-L199 WeakPolarHBondContact OD2-CG 3.3Å; D185-L199 PolarHBondContact OD2-N 3.39Å; D185-L199 VanDerWaalsContact OD2-N 3.08Å
186M92.4Very high89.2Confident0 Ų016.3 Ų16.30%08%0.084CC..Hα-helixtrans-59.4-55173.7-79.6-69.2-172.900112.2V149 V152 F182 T183 T184 C190V149-M186 HydrophobicContact CB-CE 4.27Å; V149-M186 HydrophobicContact CB-SD 4.06Å; V149-M186 HydrophobicContact CG1-CE 3.49Å; V149-M186 VanDerWaalsContact CG1-CE 3.49Å; V149-M186 HydrophobicContact CG1-SD 3.66Å; V149-M186 HydrophobicContact CG2-SD 4.24Å; V149-M186 WeakPolarHBondContact O-CE 3.48Å; V152-M186 HydrophobicContact CB-CE 3.88Å; V152-M186 HydrophobicContact CB-CG 4.5Å; V152-M186 HydrophobicContact CB-SD 3.8Å; V152-M186 HydrophobicContact CG1-CE 3.96Å; V152-M186 HydrophobicContact CG1-CG 3.9Å; V152-M186 HydrophobicContact CG1-SD 3.87Å; V152-M186 HydrophobicContact CG2-SD 4.39Å; F182-M186 HydrophobicContact CD2-CE 4.25Å; F182-M186 HydrophobicContact CD2-CG 4.32Å; F182-M186 HydrophobicContact CE1-CE 4.29Å; F182-M186 HydrophobicContact CE2-CE 3.2Å; F182-M186 HydrophobicContact CE2-CG 4.04Å; F182-M186 HydrophobicContact CE2-SD 4.48Å; F182-M186 HydrophobicContact CZ-CE 3.24Å; F182-M186 HydrophobicContact CZ-CG 4.17Å; F182-M186 VanDerWaalsContact O-CG 3.3Å; F182-M186 WeakPolarHBondContact O-CG 3.37Å; F182-M186 PolarHBondContact O-N 2.76Å; T183-M186 PolarHBondContact O-N 3Å; T184-M186 VanDerWaalsContact C-N 3.34Å; T184-M186 PolarHBondContact O-N 3.49Å; M186-C190 WeakPolarHBondContact O-CB 3.26Å; M186-C190 PolarHBondContact O-N 2.73Å; M186-C190 PolarHBondContact O-SG 3.29Å
187I89.8Confident88.8Confident8 Ų818.8 Ų18.84%0.04110%0.099CC..Hα-helixtrans-69.6-38.9-178.3-164.667.5000111.2T183 T184 T189 A191 F192 Y308 F312 F456T183-I187 WeakPolarHBondContact O-CG2 3.24Å; T183-I187 PolarHBondContact O-N 3.18Å; T184-I187 WeakPolarHBondContact O-CG2 3.47Å; T184-I187 PolarHBondContact O-N 2.89Å; I187-T189 PolarHBondContact O-N 3.06Å; I187-A191 HydrophobicContact CD1-CB 3.69Å; I187-A191 HydrophobicContact CG1-CB 4.08Å; I187-A191 WeakPolarHBondContact O-CA 3.33Å; I187-A191 WeakPolarHBondContact O-CB 3.41Å; I187-A191 PolarHBondContact O-N 3.12Å; I187-F192 HydrophobicContact CG1-CE2 4.1Å; I187-Y308 HydrophobicContact CG2-CD2 3.77Å; I187-Y308 HydrophobicContact CG2-CE2 4.05Å; I187-F312 HydrophobicContact CG2-CB 4.42Å; I187-F456 HydrophobicContact CD1-CE1 3.88Å; I187-F456 HydrophobicContact CD1-CZ 4.29Å
188G89.4Confident88.5Confident0 Ų017.8 Ų17.80%010%0.095CC..Iπ-helixtrans-55.1-52.5175.100000112.1T184 F192 G193 I194T184-G188 PolarHBondContact O-N 3.44Å; G188-F192 CarbonylContact O-C 3.5Å; G188-F192 WeakPolarHBondContact O-CA 3.49Å; G188-F192 WeakPolarHBondContact O-CB 3.39Å; G188-F192 PolarHBondContact O-N 3.47Å; G188-F192 VanDerWaalsContact O-N 3.16Å; G188-G193 PolarHBondContact O-N 2.91Å; G188-I194 CarbonylContact C-O 3.44Å; G188-I194 PolarHBondContact O-N 3.36Å
189T88.4Confident88.2Confident17 Ų1717.6 Ų17.610%0.1049%0.094CC..Iπ-helixtrans-75.2-42.7-175-49.80000112.2T148 V152 D185 I187 G193 I194 R268T148-T189 HydrophobicContact CG2-CG2 3.45Å; T148-T189 VanDerWaalsContact CG2-CG2 3.45Å; V152-T189 HydrophobicContact CG2-CG2 4.34Å; D185-T189 VanDerWaalsContact O-CB 3.25Å; D185-T189 WeakPolarHBondContact O-CB 3.33Å; D185-T189 PolarHBondContact O-N 3.13Å; D185-T189 PolarHBondContact O-OG1 3.04Å; I187-T189 PolarHBondContact O-N 3.06Å; T189-G193 WeakPolarHBondContact O-CA 3.36Å; T189-G193 PolarHBondContact O-N 2.88Å; T189-I194 PolarHBondContact N-O 3.36Å; T189-R268 PolarHBondContact O-NH2 3.22Å
190C85.4Confident87.8Confident6 Ų623.5 Ų23.54%0.04112%0.116CC..Iπ-helixtrans-81.1-42.8-174.4-61.30000112.8M145 V149 M186 F456M145-C190 HydrophobicContact SD-CB 4.23Å; V149-C190 VanDerWaalsContact CG2-SG 3.58Å; M186-C190 WeakPolarHBondContact O-CB 3.26Å; M186-C190 PolarHBondContact O-N 2.73Å; M186-C190 PolarHBondContact O-SG 3.29Å; C190-F456 HydrophobicContact CB-CE2 4.08Å; C190-F456 HydrophobicContact CB-CZ 4.18Å
191A81.2Confident87.5Confident7 Ų727.2 Ų27.26%0.05814%0.139CC..Iπ-helixtrans-86.7-43.8-177.100000111.9I187 F271 M272I187-A191 HydrophobicContact CD1-CB 3.69Å; I187-A191 HydrophobicContact CG1-CB 4.08Å; I187-A191 WeakPolarHBondContact O-CA 3.33Å; I187-A191 WeakPolarHBondContact O-CB 3.41Å; I187-A191 PolarHBondContact O-N 3.12Å; A191-F271 HydrophobicContact CB-CB 3.97Å; A191-F271 HydrophobicContact CB-CD1 4.38Å; A191-F271 WeakPolarHBondContact O-CA 3.44Å; A191-F271 VanDerWaalsContact O-CB 3.23Å; A191-F271 WeakPolarHBondContact O-CB 3.27Å; A191-F271 PolarHBondContact O-N 3.1Å; A191-M272 PolarHBondContact O-N 3.04Å
192F81.5Confident86.5Confident1 Ų127.6 Ų27.60%0.00415%0.147CC..Iπ-helixtrans-105.4-12.6-170.7-49-51.1000113.7I187 G188 I194 R261 F271 M272 V304 F307 Y308I187-F192 HydrophobicContact CG1-CE2 4.1Å; G188-F192 CarbonylContact O-C 3.5Å; G188-F192 WeakPolarHBondContact O-CA 3.49Å; G188-F192 WeakPolarHBondContact O-CB 3.39Å; G188-F192 PolarHBondContact O-N 3.47Å; G188-F192 VanDerWaalsContact O-N 3.16Å; F192-I194 HydrophobicContact CB-CB 4.44Å; F192-I194 HydrophobicContact CB-CD1 3.9Å; F192-I194 HydrophobicContact CB-CG1 3.93Å; F192-I194 PolarHBondContact O-N 3.14Å; F192-R261 PolarHBondContact O-NH2 2.9Å; F192-F271 HydrophobicContact CE1-CD1 4.02Å; F192-M272 HydrophobicContact CD1-CE 4.15Å; F192-V304 HydrophobicContact CD1-CG1 4.05Å; F192-V304 HydrophobicContact CD1-CG2 4.41Å; F192-V304 HydrophobicContact CE1-CB 4.1Å; F192-V304 HydrophobicContact CE1-CG1 3.67Å; F192-V304 HydrophobicContact CE1-CG2 4.08Å; F192-V304 HydrophobicContact CZ-CG1 3.97Å; F192-V304 WeakPolarHBondContact CZ-O 3.46Å; F192-F307 HydrophobicContact CZ-CB 4.41Å; F192-Y308 AromaticContact CE2-CD2 3.99Å; F192-Y308 HydrophobicContact CE2-CD2 3.99Å; F192-Y308 HydrophobicContact CE2-CG 4.36Å
193G80.3Confident85.5Confident17 Ų1733.4 Ų33.418%0.17518%0.182CC..  trans67.827.7-175.600000112.9G188 T189 R268G188-G193 PolarHBondContact O-N 2.91Å; T189-G193 WeakPolarHBondContact O-CA 3.36Å; T189-G193 PolarHBondContact O-N 2.88Å; G193-R268 VanDerWaalsContact C-NH1 3.32Å; G193-R268 VanDerWaalsContact CA-NH1 3.32Å; G193-R268 PolarHBondContact O-NH1 2.77Å
194I81.4Confident84.8Confident36 Ų3634.2 Ų34.219%0.18519%0.188CC..  trans-111.3126.8-176.6-58.8178.5000108.5G188 T189 F192 C196 F206 L253G188-I194 CarbonylContact C-O 3.44Å; G188-I194 PolarHBondContact O-N 3.36Å; T189-I194 PolarHBondContact N-O 3.36Å; F192-I194 HydrophobicContact CB-CB 4.44Å; F192-I194 HydrophobicContact CB-CD1 3.9Å; F192-I194 HydrophobicContact CB-CG1 3.93Å; F192-I194 PolarHBondContact O-N 3.14Å; I194-C196 PolarHBondContact O-N 3.32Å; I194-F206 HydrophobicContact CD1-CZ 4.02Å; I194-F206 HydrophobicContact CG2-CE2 4.07Å; I194-F206 HydrophobicContact CG2-CZ 4.05Å; I194-L253 HydrophobicContact CD1-CD1 3.59Å; I194-L253 HydrophobicContact CD1-CG 4.48Å
195E81.5Confident84.3Confident117 Ų11739.6 Ų39.655%0.54722%0.216SC..  trans-8294.8172.8-64-172.1171.400108.9N197E195-N197 VanDerWaalsContact C-N 3.3Å
196C81.1Confident83.7Confident15 Ų1540.3 Ų40.310%0.10122%0.219CC..  trans-73.8-23.9179.6-57.70000112.6T184 D185 I194 T198T184-C196 HydrophobicContact CG2-CB 4.45Å; D185-C196 WeakPolarHBondContact OD1-CB 3.17Å; I194-C196 PolarHBondContact O-N 3.32Å; C196-T198 HydrophobicContact CB-CG2 3.72Å; C196-T198 PolarHBondContact O-N 2.74Å; C196-T198 VanDerWaalsContact O-N 3.08Å
197N84.9Confident83.3Confident86 Ų8641 Ų4146%0.4622%0.222SC..  trans48.933.8178.7-66.9-36.5000113.9D185 E195 L199 R200 T201D185-N197 PolarHBondContact OD1-N 3.1Å; E195-N197 VanDerWaalsContact C-N 3.3Å; N197-L199 VanDerWaalsContact C-N 3.3Å; N197-L199 PolarHBondContact O-N 2.98Å; N197-R200 PolarHBondContact O-N 3.32Å; N197-T201 WeakPolarHBondContact O-CB 3.12Å; N197-T201 PolarHBondContact O-N 3.02Å
198T87.8Confident83.2Confident0 Ų042.8 Ų42.80%023%0.233CC..THydrogen-bonded Turntrans-73.4-22.9-175.166.10000112.8R181 T184 D185 C196 R200 T201 S204R181-T198 WeakPolarHBondContact CA-OG1 3.26Å; R181-T198 WeakPolarHBondContact CD-O 3.42Å; R181-T198 PolarHBondContact O-OG1 3.46Å; T184-T198 HydrophobicContact CG2-CG2 3.68Å; D185-T198 VanDerWaalsContact CG-OG1 3.27Å; D185-T198 WeakPolarHBondContact OD1-CB 3.32Å; D185-T198 WeakPolarHBondContact OD1-CG2 3.35Å; D185-T198 PolarHBondContact OD1-N 3.45Å; D185-T198 PolarHBondContact OD1-OG1 2.95Å; D185-T198 PolarHBondContact OD2-N 3.06Å; D185-T198 VanDerWaalsContact OD2-N 3.1Å; C196-T198 HydrophobicContact CB-CG2 3.72Å; C196-T198 PolarHBondContact O-N 2.74Å; C196-T198 VanDerWaalsContact O-N 3.08Å; T198-R200 VanDerWaalsContact C-N 3.3Å; T198-R200 PolarHBondContact O-N 3.47Å; T198-T201 WeakPolarHBondContact CA-O 3.5Å; T198-T201 CarbonylContact O-C 3.39Å; T198-S204 WeakPolarHBondContact CG2-OG 3.44Å
199L88.3Confident83.2Confident5 Ų544 Ų443%0.02624%0.239CC..THydrogen-bonded Turntrans-59.3-40.6172.4-75.2170.6000112.4F156 V159 R181 F182 D185 N197F156-L199 HydrophobicContact CB-CD1 3.98Å; F156-L199 HydrophobicContact CD2-CD2 3.69Å; F156-L199 HydrophobicContact CE2-CD2 4.43Å; V159-L199 HydrophobicContact CG2-CB 4.26Å; R181-L199 HydrophobicContact CB-CD2 4.01Å; R181-L199 HydrophobicContact CB-CG 4.5Å; F182-L199 HydrophobicContact CB-CD2 4.13Å; D185-L199 HydrophobicContact CB-CD1 4.49Å; D185-L199 WeakPolarHBondContact OD2-CG 3.3Å; D185-L199 PolarHBondContact OD2-N 3.39Å; D185-L199 VanDerWaalsContact OD2-N 3.08Å; N197-L199 VanDerWaalsContact C-N 3.3Å; N197-L199 PolarHBondContact O-N 2.98Å
200R88.7Confident83Confident123 Ų12343.2 Ų43.246%0.46423%0.234SC..THydrogen-bonded Turntrans-95.1-28.1179.1-68-165.4174.8-78.5-4.4113.6E155 V159 E162 N197 T198 P202E155-R200 IonicContact OE1-CZ 3.74Å; E155-R200 IonicContact OE1-NE 2.92Å; E155-R200 PolarHBondContact OE1-NE 2.97Å; E155-R200 IonicContact OE1-NH2 3.52Å; E155-R200 PolarHBondContact OE1-NH2 2.94Å; V159-R200 HydrophobicContact CG2-CG 4.01Å; E162-R200 IonicContact OE1-CZ 2.77Å; E162-R200 IonicContact OE1-NH1 3.34Å; E162-R200 PolarHBondContact OE1-NH1 3.35Å; E162-R200 IonicContact OE1-NH2 3.37Å; E162-R200 PolarHBondContact OE1-NH2 2.9Å; E162-R200 IonicContact OE2-CZ 3.25Å; E162-R200 IonicContact OE2-NH1 2.81Å; E162-R200 PolarHBondContact OE2-NH1 3.3Å; E162-R200 IonicContact OE2-NH2 2.78Å; N197-R200 PolarHBondContact O-N 3.32Å; T198-R200 VanDerWaalsContact C-N 3.3Å; T198-R200 PolarHBondContact O-N 3.47Å; R200-P202 WeakPolarHBondContact O-CD 3.44Å
201T85.2Confident83Confident80 Ų8046.4 Ų46.449%0.49125%0.249SC..  trans-11886.3179.1-46.40000109.4N197 T198 V203N197-T201 WeakPolarHBondContact O-CB 3.12Å; N197-T201 PolarHBondContact O-N 3.02Å; T198-T201 WeakPolarHBondContact CA-O 3.5Å; T198-T201 CarbonylContact O-C 3.39Å; T201-V203 PolarHBondContact O-N 2.69Å; T201-V203 VanDerWaalsContact O-N 3.15Å
202P73Confident83.4Confident52 Ų5248.7 Ų48.734%0.33826%0.258SS..SBendtrans-57.6-33-171.6-28.937.1000114.3R200R200-P202 WeakPolarHBondContact O-CD 3.44Å
203V75.1Confident83.5Confident121 Ų12150 Ų5073%0.73327%0.265SS*.  trans-97100.7178.5-174.80000108.3T201T201-V203 PolarHBondContact O-N 2.69Å; T201-V203 VanDerWaalsContact O-N 3.15Å
204S79.9Confident83.6Confident18 Ų1850.6 Ų50.613%0.12626%0.263CS..  trans-126.5154.8171.571.70000110.7T198 F206 R207 T208T198-S204 WeakPolarHBondContact CG2-OG 3.44Å; S204-F206 PolarHBondContact O-N 3.44Å; S204-R207 PolarHBondContact O-N 2.92Å; S204-R207 WeakPolarHBondContact OG-CB 3.26Å; S204-R207 PolarHBondContact OG-N 3.29Å; S204-R207 VanDerWaalsContact OG-N 3.11Å; S204-T208 WeakPolarHBondContact O-CB 3.17Å; S204-T208 PolarHBondContact O-N 3.23Å; S204-T208 PolarHBondContact O-OG1 3.3Å
205D82.3Confident83.5Confident112 Ų11252.8 Ų52.860%0.59928%0.278SS*.Hα-helixtrans-58.6-39.5174.2-72.5-13.9000111T208 M209 F249D205-T208 PolarHBondContact O-N 3.07Å; D205-M209 VanDerWaalsContact O-CB 3.3Å; D205-M209 WeakPolarHBondContact O-CB 3.46Å; D205-M209 WeakPolarHBondContact O-CG 3.43Å; D205-M209 PolarHBondContact O-N 3.29Å; D205-F249 HydrophobicContact CB-CD2 4.33Å; D205-F249 HydrophobicContact CB-CE2 3.68Å; D205-F249 HydrophobicContact CB-CZ 4.37Å
206F80.3Confident83.6Confident25 Ų2550.7 Ų50.711%0.1127%0.271CS..Hα-helixtrans-55.8-55.8175-84.7-84.6000111.6T184 I194 S204 T208 M209 G210 F249 L253 Y308T184-F206 HydrophobicContact CG2-CB 4.39Å; I194-F206 HydrophobicContact CD1-CZ 4.02Å; I194-F206 HydrophobicContact CG2-CE2 4.07Å; I194-F206 HydrophobicContact CG2-CZ 4.05Å; S204-F206 PolarHBondContact O-N 3.44Å; F206-T208 VanDerWaalsContact C-N 3.35Å; F206-T208 PolarHBondContact O-N 3.38Å; F206-M209 PolarHBondContact O-N 3.33Å; F206-G210 PolarHBondContact O-N 2.81Å; F206-F249 HydrophobicContact CD1-CE1 4.09Å; F206-F249 AromaticContact CD1-CZ 3.9Å; F206-F249 HydrophobicContact CD1-CZ 3.9Å; F206-F249 AromaticContact CD2-CZ 3.99Å; F206-F249 HydrophobicContact CD2-CZ 3.99Å; F206-F249 HydrophobicContact CE1-CE1 4.23Å; F206-F249 HydrophobicContact CE1-CZ 4.03Å; F206-F249 HydrophobicContact CE2-CZ 4.11Å; F206-F249 HydrophobicContact CG-CE1 4.47Å; F206-F249 AromaticContact CG-CZ 3.9Å; F206-F249 HydrophobicContact CG-CZ 3.9Å; F206-F249 HydrophobicContact CZ-CZ 4.14Å; F206-L253 HydrophobicContact CE1-CD1 4.31Å; F206-L253 HydrophobicContact CE1-CD2 3.58Å; F206-L253 HydrophobicContact CE2-CD1 4.41Å; F206-L253 HydrophobicContact CZ-CD1 3.58Å; F206-L253 HydrophobicContact CZ-CD2 3.75Å; F206-L253 HydrophobicContact CZ-CG 4.32Å; F206-Y308 HydrophobicContact CD1-CD2 4.37Å; F206-Y308 AromaticContact CD1-CE2 3.81Å; F206-Y308 HydrophobicContact CD1-CE2 3.81Å; F206-Y308 PolarHBondContact O-OH 3.23Å
207R84.7Confident83.8Confident14 Ų1451.9 Ų51.95%0.05328%0.275CS..Hα-helixtrans-60.8-45.6-177.9-179.364.5-176.9124.3-0.2111.3E177 A180 S204 G210 Q211E177-R207 IonicContact OE1-NE 3.62Å; E177-R207 IonicContact OE2-CZ 3.94Å; E177-R207 IonicContact OE2-NE 3.58Å; E177-R207 PolarHBondContact OE2-NE 3.19Å; E177-R207 IonicContact OE2-NH2 3.5Å; E177-R207 PolarHBondContact OE2-NH2 2.73Å; A180-R207 VanDerWaalsContact CB-CZ 3.45Å; A180-R207 VanDerWaalsContact CB-NH2 3.34Å; S204-R207 PolarHBondContact O-N 2.92Å; S204-R207 WeakPolarHBondContact OG-CB 3.26Å; S204-R207 PolarHBondContact OG-N 3.29Å; S204-R207 VanDerWaalsContact OG-N 3.11Å; R207-G210 PolarHBondContact O-N 3.33Å; R207-Q211 WeakPolarHBondContact O-CG 3.29Å; R207-Q211 PolarHBondContact O-N 2.93Å
208T87.5Confident83.9Confident47 Ų4751.6 Ų51.629%0.28827%0.268SS..Hα-helixtrans-63-48.8-178.8-54.30000111.2S204 D205 F206 G210 Q211 K212S204-T208 WeakPolarHBondContact O-CB 3.17Å; S204-T208 PolarHBondContact O-N 3.23Å; S204-T208 PolarHBondContact O-OG1 3.3Å; D205-T208 PolarHBondContact O-N 3.07Å; F206-T208 VanDerWaalsContact C-N 3.35Å; F206-T208 PolarHBondContact O-N 3.38Å; T208-G210 VanDerWaalsContact C-N 3.33Å; T208-G210 PolarHBondContact O-N 2.94Å; T208-Q211 PolarHBondContact O-N 3.46Å; T208-K212 WeakPolarHBondContact O-CG 3.41Å; T208-K212 PolarHBondContact O-N 3.25Å
209M89.3Confident83.9Confident25 Ų2554.7 Ų54.712%0.12328%0.282CS..Hα-helixtrans-67.3-35.8179.1-63.9-57.8133.800111.7D205 F206 K212 V213 D245 V246 F249D205-M209 VanDerWaalsContact O-CB 3.3Å; D205-M209 WeakPolarHBondContact O-CB 3.46Å; D205-M209 WeakPolarHBondContact O-CG 3.43Å; D205-M209 PolarHBondContact O-N 3.29Å; F206-M209 PolarHBondContact O-N 3.33Å; M209-K212 PolarHBondContact O-N 2.66Å; M209-K212 HydrophobicContact SD-CD 4.46Å; M209-V213 WeakPolarHBondContact O-CG2 3.44Å; M209-D245 HydrophobicContact SD-CB 4.36Å; M209-V246 HydrophobicContact SD-CG2 4.24Å; M209-F249 HydrophobicContact CB-CD1 3.87Å; M209-F249 HydrophobicContact CB-CE1 4.25Å; M209-F249 HydrophobicContact CB-CG 4.18Å; M209-F249 HydrophobicContact CG-CB 3.92Å; M209-F249 HydrophobicContact CG-CD1 3.88Å; M209-F249 HydrophobicContact CG-CD2 4.01Å; M209-F249 HydrophobicContact CG-CE1 4.42Å; M209-F249 HydrophobicContact CG-CG 3.66Å; M209-F249 HydrophobicContact SD-CB 4.38Å
210G84.6Confident83.8Confident0 Ų056 Ų560%030%0.297CS..Hα-helixtrans-60.1-46.4173.300000113.1F206 R207 T208 V213 F312F206-G210 PolarHBondContact O-N 2.81Å; R207-G210 PolarHBondContact O-N 3.33Å; T208-G210 VanDerWaalsContact C-N 3.33Å; T208-G210 PolarHBondContact O-N 2.94Å; G210-V213 WeakPolarHBondContact O-CB 3.29Å; G210-V213 PolarHBondContact O-N 2.92Å; G210-F312 WeakPolarHBondContact O-CZ 3.47Å
211Q84.9Confident83.5Confident74 Ų7455.1 Ų55.135%0.34630%0.296SS..Hα-helixtrans-61.6-44.7178-73.8175.8-16.400112.1R207 T208 V213 F214 T215R207-Q211 WeakPolarHBondContact O-CG 3.29Å; R207-Q211 PolarHBondContact O-N 2.93Å; T208-Q211 PolarHBondContact O-N 3.46Å; Q211-V213 PolarHBondContact O-N 3.43Å; Q211-V213 VanDerWaalsContact O-N 3.11Å; Q211-F214 PolarHBondContact O-N 3.4Å; Q211-T215 PolarHBondContact O-N 3.05Å; Q211-T215 PolarHBondContact O-OG1 3.25Å
212K88.1Confident83.4Confident55 Ų5558.1 Ų58.124%0.23931%0.308CS..Hα-helixtrans-57.7-28.5-177.9-74.8-172.7178.1-163.90113.8T208 M209 F214 T215 D216 D245 V246T208-K212 WeakPolarHBondContact O-CG 3.41Å; T208-K212 PolarHBondContact O-N 3.25Å; M209-K212 PolarHBondContact O-N 2.66Å; M209-K212 HydrophobicContact SD-CD 4.46Å; K212-F214 PolarHBondContact O-N 3.24Å; K212-T215 PolarHBondContact O-N 3.2Å; K212-D216 HydrophobicContact CB-CB 4.46Å; K212-D216 WeakPolarHBondContact O-CB 3.43Å; K212-D216 PolarHBondContact O-N 2.67Å; K212-D245 WeakPolarHBondContact CD-OD2 3.4Å; K212-D245 IonicContact NZ-OD2 3.48Å; K212-D245 PolarHBondContact NZ-OD2 3.13Å; K212-V246 HydrophobicContact CB-CG2 3.87Å
213V85.3Confident84.1Confident27 Ų2759.6 Ų59.616%0.16431%0.313CS..Hα-helixtrans-58.5-31.8176.2177.40000112.3M209 G210 Q211 V246 F305 V309M209-V213 WeakPolarHBondContact O-CG2 3.44Å; G210-V213 WeakPolarHBondContact O-CB 3.29Å; G210-V213 PolarHBondContact O-N 2.92Å; Q211-V213 PolarHBondContact O-N 3.43Å; Q211-V213 VanDerWaalsContact O-N 3.11Å; V213-V246 HydrophobicContact CG2-CG1 3.84Å; V213-F305 HydrophobicContact CG1-CE2 4.33Å; V213-F305 HydrophobicContact CG1-CZ 3.85Å; V213-F305 HydrophobicContact CG2-CE2 3.57Å; V213-F305 HydrophobicContact CG2-CZ 3.93Å; V213-V309 HydrophobicContact CB-CG2 4.39Å; V213-V309 HydrophobicContact CG1-CG1 3.97Å; V213-V309 HydrophobicContact CG1-CG2 4.14Å; V213-V309 HydrophobicContact CG2-CG2 4.02Å
214F81.2Confident84.6Confident31 Ų3154.7 Ų54.714%0.13628%0.283CS..Hα-helixtrans-97.9-25-176.4-63.5-79.7000113.5Q211 K212 V309 F312 E313 V492Q211-F214 PolarHBondContact O-N 3.4Å; K212-F214 PolarHBondContact O-N 3.24Å; F214-V309 HydrophobicContact CE1-CG1 4.19Å; F214-V309 HydrophobicContact CE2-CG1 3.59Å; F214-V309 HydrophobicContact CZ-CG1 3.27Å; F214-F312 HydrophobicContact CD2-CZ 4.19Å; F214-F312 HydrophobicContact CE2-CE1 4.13Å; F214-F312 HydrophobicContact CE2-CE2 4.47Å; F214-F312 AromaticContact CE2-CZ 3.66Å; F214-F312 HydrophobicContact CE2-CZ 3.66Å; F214-E313 HydrophobicContact CD2-CB 4.38Å; F214-E313 HydrophobicContact CD2-CG 4.12Å; F214-E313 HydrophobicContact CE1-CB 4.43Å; F214-E313 HydrophobicContact CE1-CG 4.13Å; F214-E313 HydrophobicContact CE2-CB 3.52Å; F214-E313 HydrophobicContact CE2-CG 3.68Å; F214-E313 HydrophobicContact CZ-CB 3.53Å; F214-E313 HydrophobicContact CZ-CG 3.67Å; F214-V492 HydrophobicContact CD1-CG2 4.33Å; F214-V492 HydrophobicContact CE1-CG1 4.47Å; F214-V492 HydrophobicContact CE1-CG2 4.32Å
215T79.4Confident84.8Confident81 Ų8155.9 Ų55.950%0.49729%0.288SS..Hα-helixtrans-99.5-35.9-174.8580000113.4Q211 K212Q211-T215 PolarHBondContact O-N 3.05Å; Q211-T215 PolarHBondContact O-OG1 3.25Å; K212-T215 PolarHBondContact O-N 3.2Å
216D84.6Confident85Confident74 Ų7453.3 Ų53.340%0.39627%0.271SS..  trans-98.2144.7-165.6-65.712.5000111.4K212 P243K212-D216 HydrophobicContact CB-CB 4.46Å; K212-D216 WeakPolarHBondContact O-CB 3.43Å; K212-D216 PolarHBondContact O-N 2.67Å; D216-P243 HydrophobicContact CB-CG 4.24Å
217M84.6Confident85.3Confident40 Ų4052.3 Ų52.320%0.19727%0.267CS..  trans-119.7117.2174-66.9179.8-179.200109.5H219 G220 K221 T224 M489M217-H219 PolarHBondContact O-N 3.43Å; M217-H219 VanDerWaalsContact O-N 3.09Å; M217-G220 PolarHBondContact O-N 3.47Å; M217-K221 HydrophobicContact CE-CG 4.27Å; M217-K221 HydrophobicContact SD-CB 4.36Å; M217-K221 HydrophobicContact SD-CG 3.89Å; M217-T224 HydrophobicContact SD-CG2 4.33Å; M217-M489 HydrophobicContact CE-CE 3.86Å
218R87.9Confident85.2Confident80 Ų8054.1 Ų54.130%0.30228%0.276SS..THydrogen-bonded Turntrans-49.6-42.1179.8-170.5-165.7-179.983.94113.3R240 M242 E244R218-R240 VanDerWaalsContact CD-O 3.25Å; R218-R240 WeakPolarHBondContact CD-O 3.17Å; R218-M242 VanDerWaalsContact CD-O 3.28Å; R218-M242 WeakPolarHBondContact CD-O 3.49Å; R218-M242 PolarHBondContact NH1-O 3.15Å; R218-E244 IonicContact CZ-OE2 3.73Å; R218-E244 VanDerWaalsContact CZ-OE2 3.25Å; R218-E244 IonicContact NH1-OE2 3.3Å; R218-E244 PolarHBondContact NH1-OE2 3.5Å; R218-E244 IonicContact NH2-OE2 3.55Å; R218-E244 PolarHBondContact NH2-OE2 3.07Å
219H86.4Confident85Confident65 Ų6552.6 Ų52.630%0.30127%0.266SS..THydrogen-bonded Turntrans-113.410.4-172.3-60.9-52.3000113.7M217 L223 R240M217-H219 PolarHBondContact O-N 3.43Å; M217-H219 VanDerWaalsContact O-N 3.09Å; H219-L223 HydrophobicContact CB-CB 3.43Å; H219-L223 VanDerWaalsContact CB-CB 3.43Å; H219-L223 HydrophobicContact CB-CD1 3.84Å; H219-L223 HydrophobicContact CB-CG 4.29Å; H219-R240 PolarHBondContact CD2-O 2.75Å; H219-R240 PolarHBondContact NE2-O 3.02Å
220G86.3Confident84.8Confident32 Ų3256 Ų5633%0.3328%0.281SS..Hα-helixtrans65179.1-171.300000113.8M217 L222 T224M217-G220 PolarHBondContact O-N 3.47Å; G220-L222 PolarHBondContact O-N 3.01Å; G220-T224 VanDerWaalsContact O-CB 3.28Å; G220-T224 WeakPolarHBondContact O-CB 3.17Å; G220-T224 PolarHBondContact O-N 2.98Å; G220-T224 VanDerWaalsContact O-N 3.1Å; G220-T224 PolarHBondContact O-OG1 3.2Å
221K82.8Confident84.8Confident105 Ų10557.2 Ų57.246%0.45729%0.289SS..Hα-helixtrans-59.7-46.5-166.8-61-173.7-178.2-169.50114R47 M217 M225R47-K221 PolarHBondContact O-NZ 3.46Å; M217-K221 HydrophobicContact CE-CG 4.27Å; M217-K221 HydrophobicContact SD-CB 4.36Å; M217-K221 HydrophobicContact SD-CG 3.89Å; K221-M225 HydrophobicContact CB-CE 4.42Å; K221-M225 WeakPolarHBondContact O-CB 3.24Å; K221-M225 WeakPolarHBondContact O-CE 3.41Å; K221-M225 VanDerWaalsContact O-CG 3.32Å; K221-M225 WeakPolarHBondContact O-CG 3.26Å; K221-M225 PolarHBondContact O-N 2.98Å
222L84.1Confident84.9Confident142 Ų14261.2 Ų61.274%0.74331%0.305SS*.Hα-helixtrans-65.4-50.2-172.6-68.4174.7000112.6G220 M225 F226G220-L222 PolarHBondContact O-N 3.01Å; L222-M225 HydrophobicContact CD2-CE 3.8Å; L222-M225 WeakPolarHBondContact O-CB 3.49Å; L222-M225 PolarHBondContact O-N 3.31Å; L222-F226 PolarHBondContact O-N 3.16Å
223L87.1Confident84.9Confident84 Ų8462.3 Ų62.344%0.4431%0.313SS..Hα-helixtrans-71.7-33.7179.8-74.2173.7000111.7H219 F226 V227 M239H219-L223 HydrophobicContact CB-CB 3.43Å; H219-L223 VanDerWaalsContact CB-CB 3.43Å; H219-L223 HydrophobicContact CB-CD1 3.84Å; H219-L223 HydrophobicContact CB-CG 4.29Å; L223-F226 WeakPolarHBondContact O-CB 3.43Å; L223-F226 PolarHBondContact O-N 3.02Å; L223-V227 WeakPolarHBondContact O-CG2 3.2Å; L223-V227 PolarHBondContact O-N 3.19Å; L223-M239 HydrophobicContact CB-CE 4.27Å; L223-M239 HydrophobicContact CD2-CE 4.19Å
224T85.5Confident85.1Confident17 Ų1761 Ų6110%0.10431%0.305CS..Hα-helixtrans-61.4-43.7170.7-67.50000111.4M217 G220 F226 V227 F228M217-T224 HydrophobicContact SD-CG2 4.33Å; G220-T224 VanDerWaalsContact O-CB 3.28Å; G220-T224 WeakPolarHBondContact O-CB 3.17Å; G220-T224 PolarHBondContact O-N 2.98Å; G220-T224 VanDerWaalsContact O-N 3.1Å; G220-T224 PolarHBondContact O-OG1 3.2Å; T224-F226 VanDerWaalsContact C-N 3.3Å; T224-F226 PolarHBondContact O-N 2.9Å; T224-V227 PolarHBondContact O-N 3.41Å; T224-F228 HydrophobicContact CG2-CD2 3.77Å; T224-F228 HydrophobicContact CG2-CE2 3.46Å; T224-F228 VanDerWaalsContact CG2-CE2 3.46Å; T224-F228 WeakPolarHBondContact O-CD2 3.1Å; T224-F228 PolarHBondContact O-N 2.91Å; T224-F228 VanDerWaalsContact O-N 3.1Å
225M83.1Confident85.4Confident44 Ų4461.6 Ų61.622%0.21731%0.313CS..Hα-helixtrans-59.3-41.2172.8-75.6-176-68.200111.5L76 K221 L222 V227 F228 S229L76-M225 HydrophobicContact CD1-CB 4.36Å; L76-M225 HydrophobicContact CD1-CG 4.19Å; K221-M225 HydrophobicContact CB-CE 4.42Å; K221-M225 WeakPolarHBondContact O-CB 3.24Å; K221-M225 WeakPolarHBondContact O-CE 3.41Å; K221-M225 VanDerWaalsContact O-CG 3.32Å; K221-M225 WeakPolarHBondContact O-CG 3.26Å; K221-M225 PolarHBondContact O-N 2.98Å; L222-M225 HydrophobicContact CD2-CE 3.8Å; L222-M225 WeakPolarHBondContact O-CB 3.49Å; L222-M225 PolarHBondContact O-N 3.31Å; M225-V227 PolarHBondContact O-N 3.1Å; M225-F228 PolarHBondContact O-N 3.21Å; M225-S229 WeakPolarHBondContact O-CB 3.34Å; M225-S229 PolarHBondContact O-N 3.5Å; M225-S229 PolarHBondContact O-OG 2.96Å
226F86.8Confident85.9Confident58 Ų5867.2 Ų67.225%0.25433%0.325SS..Hα-helixtrans-60-43.1174.9174-95.8000112.8L222 L223 T224 S229 F230 L233 A234 L237 M239L222-F226 PolarHBondContact O-N 3.16Å; L223-F226 WeakPolarHBondContact O-CB 3.43Å; L223-F226 PolarHBondContact O-N 3.02Å; T224-F226 VanDerWaalsContact C-N 3.3Å; T224-F226 PolarHBondContact O-N 2.9Å; F226-S229 WeakPolarHBondContact O-CB 3.36Å; F226-S229 PolarHBondContact O-N 3.01Å; F226-F230 AromaticContact CD2-CD2 3.73Å; F226-F230 HydrophobicContact CD2-CD2 3.73Å; F226-F230 HydrophobicContact CD2-CE2 4.36Å; F226-F230 HydrophobicContact CE2-CB 4.36Å; F226-F230 AromaticContact CE2-CD2 3.84Å; F226-F230 HydrophobicContact CE2-CD2 3.84Å; F226-F230 HydrophobicContact CE2-CG 4.38Å; F226-F230 PolarHBondContact O-N 3.01Å; F226-L233 HydrophobicContact CE2-CD2 4.14Å; F226-L233 HydrophobicContact CZ-CD2 3.75Å; F226-L233 HydrophobicContact CZ-CG 4.03Å; F226-A234 HydrophobicContact CE1-CB 4.27Å; F226-L237 HydrophobicContact CE1-CD1 4.01Å; F226-L237 HydrophobicContact CZ-CD1 4Å; F226-M239 HydrophobicContact CD1-CE 4.34Å; F226-M239 HydrophobicContact CD1-SD 3.69Å; F226-M239 HydrophobicContact CE1-SD 3.66Å
227V87.4Confident86.2Confident4 Ų468.7 Ų68.72%0.02433%0.333CS..Hα-helixtrans-61.8-49177.8173.70000111.3F106 L223 T224 M225 S229 F230 P231 A234 M239F106-V227 HydrophobicContact CB-CG1 4.25Å; F106-V227 HydrophobicContact CD1-CG1 3.8Å; F106-V227 HydrophobicContact CD2-CG1 3.75Å; F106-V227 HydrophobicContact CE1-CG1 4.04Å; F106-V227 HydrophobicContact CE2-CG1 3.98Å; F106-V227 HydrophobicContact CG-CG1 3.65Å; F106-V227 HydrophobicContact CZ-CG1 4.12Å; L223-V227 WeakPolarHBondContact O-CG2 3.2Å; L223-V227 PolarHBondContact O-N 3.19Å; T224-V227 PolarHBondContact O-N 3.41Å; M225-V227 PolarHBondContact O-N 3.1Å; V227-S229 PolarHBondContact O-N 3.13Å; V227-F230 CarbonylContact O-C 3.3Å; V227-F230 PolarHBondContact O-N 3.35Å; V227-P231 VanDerWaalsContact O-CA 3.31Å; V227-P231 WeakPolarHBondContact O-CA 3.35Å; V227-A234 HydrophobicContact CB-CB 4.29Å; V227-A234 HydrophobicContact CG1-CB 4.24Å; V227-A234 HydrophobicContact CG2-CB 4.03Å; V227-M239 HydrophobicContact CG2-CB 4.35Å; V227-M239 HydrophobicContact CG2-CE 3.66Å; V227-M239 HydrophobicContact CG2-SD 3.87Å
228F82.1Confident86.5Confident52 Ų5273.8 Ų73.823%0.22835%0.35CS..Hα-helixtrans-61.2-35175.3-76.6-62.6000111.8K78 T224 M225 M241K78-F228 WeakPolarHBondContact CE-O 3.18Å; K78-F228 PolarHBondContact NZ-O 3.41Å; T224-F228 HydrophobicContact CG2-CD2 3.77Å; T224-F228 HydrophobicContact CG2-CE2 3.46Å; T224-F228 VanDerWaalsContact CG2-CE2 3.46Å; T224-F228 WeakPolarHBondContact O-CD2 3.1Å; T224-F228 PolarHBondContact O-N 2.91Å; T224-F228 VanDerWaalsContact O-N 3.1Å; M225-F228 PolarHBondContact O-N 3.21Å; F228-M241 HydrophobicContact CZ-SD 4.34Å
229S82.6Confident86.7Confident14 Ų1471.2 Ų71.210%0.09834%0.341CS..Hα-helixtrans-76.5-37.4-174.6-71.80000113.3H77 K78 M225 F226 V227H77-S229 WeakPolarHBondContact CE1-CA 3Å; H77-S229 WeakPolarHBondContact CE1-CB 3.37Å; H77-S229 PolarHBondContact CE1-O 3.17Å; H77-S229 PolarHBondContact CE1-OG 3.29Å; H77-S229 VanDerWaalsContact CE1-OG 3.25Å; H77-S229 WeakPolarHBondContact ND1-CB 3.26Å; H77-S229 PolarHBondContact ND1-OG 3.47Å; H77-S229 PolarHBondContact NE2-O 3.13Å; H77-S229 VanDerWaalsContact NE2-O 3.17Å; K78-S229 WeakPolarHBondContact CE-O 3.15Å; M225-S229 WeakPolarHBondContact O-CB 3.34Å; M225-S229 PolarHBondContact O-N 3.5Å; M225-S229 PolarHBondContact O-OG 2.96Å; F226-S229 WeakPolarHBondContact O-CB 3.36Å; F226-S229 PolarHBondContact O-N 3.01Å; V227-S229 PolarHBondContact O-N 3.13Å
230F85.1Confident86.9Confident96 Ų9670.2 Ų70.242%0.42134%0.335SS..  trans-135.461.5-174.7-56.7-81.2000110.8H77 F226 V227 K232 L233 A234H77-F230 AromaticContact CD2-CE1 3.82Å; H77-F230 AromaticContact CD2-CE2 3.92Å; H77-F230 AromaticContact CD2-CZ 3.33Å; H77-F230 WeakPolarHBondContact CD2-CZ 3.3Å; H77-F230 AromaticContact NE2-CD1 3.9Å; H77-F230 AromaticContact NE2-CE1 3.32Å; H77-F230 VanDerWaalsContact NE2-CE1 3.32Å; H77-F230 WeakPolarHBondContact NE2-CE1 3.4Å; H77-F230 AromaticContact NE2-CE2 3.54Å; H77-F230 AromaticContact NE2-CZ 3.13Å; H77-F230 WeakPolarHBondContact NE2-CZ 3.47Å; F226-F230 AromaticContact CD2-CD2 3.73Å; F226-F230 HydrophobicContact CD2-CD2 3.73Å; F226-F230 HydrophobicContact CD2-CE2 4.36Å; F226-F230 HydrophobicContact CE2-CB 4.36Å; F226-F230 AromaticContact CE2-CD2 3.84Å; F226-F230 HydrophobicContact CE2-CD2 3.84Å; F226-F230 HydrophobicContact CE2-CG 4.38Å; F226-F230 PolarHBondContact O-N 3.01Å; V227-F230 CarbonylContact O-C 3.3Å; V227-F230 PolarHBondContact O-N 3.35Å; F230-K232 VanDerWaalsContact C-N 3.29Å; F230-K232 PolarHBondContact O-N 2.98Å; F230-L233 HydrophobicContact CB-CB 3.97Å; F230-L233 PolarHBondContact O-N 3.48Å; F230-A234 PolarHBondContact O-N 3.4Å
231P86.3Confident87Confident26 Ų2670.7 Ų70.717%0.16933%0.329CS..Hα-helixtrans-59.8-38-169.422.4-34.4000113K78 F106 V227 A234 S235K78-P231 VanDerWaalsContact NZ-CD 3.25Å; F106-P231 HydrophobicContact CB-CB 4.03Å; F106-P231 HydrophobicContact CD2-CB 3.81Å; F106-P231 HydrophobicContact CG-CB 4.43Å; V227-P231 VanDerWaalsContact O-CA 3.31Å; V227-P231 WeakPolarHBondContact O-CA 3.35Å; P231-A234 PolarHBondContact O-N 2.91Å; P231-S235 WeakPolarHBondContact O-CB 2.84Å; P231-S235 PolarHBondContact O-N 2.94Å
232K86.1Confident87.4Confident159 Ų15966.7 Ų66.769%0.69131%0.312SS*.Hα-helixtrans-64.6-39.4175.7-67.6-175.4177.5-177.70112.5F230 R236F230-K232 VanDerWaalsContact C-N 3.29Å; F230-K232 PolarHBondContact O-N 2.98Å; K232-R236 WeakPolarHBondContact O-CG 3.5Å; K232-R236 PolarHBondContact O-N 3.12Å
233L87.9Confident87.8Confident78 Ų7860.4 Ų60.441%0.40828%0.28SS..Hα-helixtrans-73.4-44178.4-178.258.8000110.5F226 F230 S235 R236 L237F226-L233 HydrophobicContact CE2-CD2 4.14Å; F226-L233 HydrophobicContact CZ-CD2 3.75Å; F226-L233 HydrophobicContact CZ-CG 4.03Å; F230-L233 HydrophobicContact CB-CB 3.97Å; F230-L233 PolarHBondContact O-N 3.48Å; L233-S235 VanDerWaalsContact C-N 3.3Å; L233-S235 PolarHBondContact O-N 3.24Å; L233-R236 WeakPolarHBondContact O-CB 3.23Å; L233-R236 PolarHBondContact O-N 2.95Å; L233-R236 VanDerWaalsContact O-N 3.1Å; L233-L237 HydrophobicContact CD1-CD1 4.43Å; L233-L237 HydrophobicContact CD1-CG 4.4Å; L233-L237 HydrophobicContact CG-CD1 4.14Å; L233-L237 WeakPolarHBondContact O-CG 3.44Å; L233-L237 PolarHBondContact O-N 2.96Å
234A90Very high88Confident0 Ų059.5 Ų59.50%027%0.273CS..Hα-helixtrans-57.1-42.4175.100000112.3F106 F226 V227 F230 P231 L237 R238 M239F106-A234 HydrophobicContact CD2-CB 4.47Å; F106-A234 HydrophobicContact CE2-CB 3.93Å; F226-A234 HydrophobicContact CE1-CB 4.27Å; V227-A234 HydrophobicContact CB-CB 4.29Å; V227-A234 HydrophobicContact CG1-CB 4.24Å; V227-A234 HydrophobicContact CG2-CB 4.03Å; F230-A234 PolarHBondContact O-N 3.4Å; P231-A234 PolarHBondContact O-N 2.91Å; A234-L237 CarbonylContact O-C 3.56Å; A234-L237 PolarHBondContact O-N 2.96Å; A234-R238 PolarHBondContact O-N 2.9Å; A234-M239 HydrophobicContact CB-CB 4.32Å; A234-M239 HydrophobicContact CB-CG 4.45Å; A234-M239 HydrophobicContact CB-SD 3.96Å; A234-M239 WeakPolarHBondContact O-CB 3.36Å; A234-M239 PolarHBondContact O-N 3.37Å
235S87.3Confident88.4Confident43 Ų4361.4 Ų61.430%0.30128%0.283SS..Hα-helixtrans-64.4-41.3174.3172.20000112P231 L233 L237 R238P231-S235 WeakPolarHBondContact O-CB 2.84Å; P231-S235 PolarHBondContact O-N 2.94Å; L233-S235 VanDerWaalsContact C-N 3.3Å; L233-S235 PolarHBondContact O-N 3.24Å; S235-L237 VanDerWaalsContact C-N 3.27Å; S235-L237 PolarHBondContact O-N 3.48Å; S235-R238 PolarHBondContact O-N 2.99Å
236R89.3Confident88.9Confident199 Ų19959.3 Ų59.375%0.75127%0.273SS*.Hα-helixtrans-63.2-33.5174-73.1175.6-174.7174.9-0.2113K232 L233 R238K232-R236 WeakPolarHBondContact O-CG 3.5Å; K232-R236 PolarHBondContact O-N 3.12Å; L233-R236 WeakPolarHBondContact O-CB 3.23Å; L233-R236 PolarHBondContact O-N 2.95Å; L233-R236 VanDerWaalsContact O-N 3.1Å; R236-R238 PolarHBondContact O-N 2.83Å
237L91.5Very high89.2Confident105 Ų10557.3 Ų57.355%0.5526%0.264SS..THydrogen-bonded Turntrans-79.65.8174.4-66175.2000113.2F226 L233 A234 S235 M239F226-L237 HydrophobicContact CE1-CD1 4.01Å; F226-L237 HydrophobicContact CZ-CD1 4Å; L233-L237 HydrophobicContact CD1-CD1 4.43Å; L233-L237 HydrophobicContact CD1-CG 4.4Å; L233-L237 HydrophobicContact CG-CD1 4.14Å; L233-L237 WeakPolarHBondContact O-CG 3.44Å; L233-L237 PolarHBondContact O-N 2.96Å; A234-L237 CarbonylContact O-C 3.56Å; A234-L237 PolarHBondContact O-N 2.96Å; S235-L237 VanDerWaalsContact C-N 3.27Å; S235-L237 PolarHBondContact O-N 3.48Å; L237-M239 HydrophobicContact CB-CG 4.11Å; L237-M239 PolarHBondContact O-N 3.16Å
238R91.6Very high89.5Confident147 Ų14761 Ų6156%0.55528%0.281SS*.THydrogen-bonded Turntrans5731179.9-53.5-172.2-175.2177.62.2113.6D111 A234 S235 R236D111-R238 HydrophobicContact CB-CB 4.45Å; D111-R238 WeakPolarHBondContact OD2-CB 3.33Å; D111-R238 WeakPolarHBondContact OD2-CG 3.36Å; A234-R238 PolarHBondContact O-N 2.9Å; S235-R238 PolarHBondContact O-N 2.99Å; R236-R238 PolarHBondContact O-N 2.83Å
239M91.4Very high90Very high25 Ų2559.5 Ų59.512%0.12328%0.275CS..  trans-68.4148177.2-64.6-172.575.800110.6N108 L223 F226 V227 A234 L237N108-M239 PolarHBondContact ND2-O 3.21Å; L223-M239 HydrophobicContact CB-CE 4.27Å; L223-M239 HydrophobicContact CD2-CE 4.19Å; F226-M239 HydrophobicContact CD1-CE 4.34Å; F226-M239 HydrophobicContact CD1-SD 3.69Å; F226-M239 HydrophobicContact CE1-SD 3.66Å; V227-M239 HydrophobicContact CG2-CB 4.35Å; V227-M239 HydrophobicContact CG2-CE 3.66Å; V227-M239 HydrophobicContact CG2-SD 3.87Å; A234-M239 HydrophobicContact CB-CB 4.32Å; A234-M239 HydrophobicContact CB-CG 4.45Å; A234-M239 HydrophobicContact CB-SD 3.96Å; A234-M239 WeakPolarHBondContact O-CB 3.36Å; A234-M239 PolarHBondContact O-N 3.37Å; L237-M239 HydrophobicContact CB-CG 4.11Å; L237-M239 PolarHBondContact O-N 3.16Å
240R91.2Very high90.5Very high44 Ų4458.9 Ų58.917%0.16627%0.27CS..  trans-114.3138.8176.4-59.2-179.262.5-170.4-4.7108.7D111 D112 R218 H219 E244 H247D111-R240 HydrophobicContact CB-CG 4.38Å; D111-R240 WeakPolarHBondContact O-CD 3.32Å; D111-R240 WeakPolarHBondContact O-CG 3.47Å; D111-R240 PolarHBondContact O-NE 2.9Å; D112-R240 HydrophobicContact CB-CB 4.09Å; D112-R240 HydrophobicContact CB-CG 4.05Å; R218-R240 VanDerWaalsContact CD-O 3.25Å; R218-R240 WeakPolarHBondContact CD-O 3.17Å; H219-R240 PolarHBondContact CD2-O 2.75Å; H219-R240 PolarHBondContact NE2-O 3.02Å; R240-E244 IonicContact CZ-OE1 3.08Å; R240-E244 IonicContact CZ-OE2 2.88Å; R240-E244 VanDerWaalsContact NH1-CD 3.34Å; R240-E244 IonicContact NH1-OE1 2.75Å; R240-E244 PolarHBondContact NH1-OE1 2.72Å; R240-E244 VanDerWaalsContact NH1-OE1 3.15Å; R240-E244 IonicContact NH1-OE2 3.9Å; R240-E244 PolarHBondContact NH1-OE2 3.43Å; R240-E244 IonicContact NH2-OE1 3.5Å; R240-E244 PolarHBondContact NH2-OE1 2.78Å; R240-E244 IonicContact NH2-OE2 2.84Å; R240-E244 PolarHBondContact NH2-OE2 3.46Å; R240-H247 PolarHBondContact NH2-CD2 2.87Å; R240-H247 PolarHBondContact NH2-ND1 3.28Å; R240-H247 PolarHBondContact NH2-NE2 2.68Å
241M89.1Confident90.9Very high43 Ų4355.6 Ų55.621%0.21226%0.256CS..  trans-95.4-36.1177.7-171.6168.665.200111.4F106 D112 T115 F228F106-M241 HydrophobicContact CD1-CB 4.2Å; F106-M241 HydrophobicContact CD1-CE 4.28Å; F106-M241 HydrophobicContact CD1-SD 4.14Å; F106-M241 HydrophobicContact CE1-CB 4.01Å; D112-M241 WeakPolarHBondContact OD2-CA 3.48Å; D112-M241 PolarHBondContact OD2-N 2.77Å; T115-M241 HydrophobicContact CG2-CB 4.31Å; T115-M241 HydrophobicContact CG2-CE 4.04Å; F228-M241 HydrophobicContact CZ-SD 4.34Å
242M91.1Very high91.2Very high20 Ų2061.2 Ų61.210%0.09927%0.274CS..SBendtrans-73.1135.4-176.2-68.3-6293.900112.9D112 L114 T115 R218 F305D112-M242 PolarHBondContact OD2-N 3.37Å; L114-M242 HydrophobicContact CB-CG 4.11Å; T115-M242 HydrophobicContact CG2-CG 4.3Å; R218-M242 VanDerWaalsContact CD-O 3.28Å; R218-M242 WeakPolarHBondContact CD-O 3.49Å; R218-M242 PolarHBondContact NH1-O 3.15Å; M242-F305 HydrophobicContact SD-CE1 4Å; M242-F305 HydrophobicContact SD-CE2 4.25Å; M242-F305 HydrophobicContact SD-CZ 3.51Å; M242-F305 VanDerWaalsContact SD-CZ 3.51Å
243P92.1Very high91.4Very high10 Ų1054.6 Ų54.67%0.06525%0.246CC..  trans-51.3142.5166-25.135000111.2D216 D245 V246 H247D216-P243 HydrophobicContact CB-CG 4.24Å; P243-D245 VanDerWaalsContact CB-OD1 3.28Å; P243-D245 WeakPolarHBondContact CB-OD1 3.37Å; P243-D245 PolarHBondContact O-N 2.96Å; P243-V246 HydrophobicContact CB-CB 4.19Å; P243-V246 HydrophobicContact CB-CG2 3.96Å; P243-V246 HydrophobicContact CG-CG2 4.23Å; P243-V246 PolarHBondContact O-N 3.49Å; P243-H247 WeakPolarHBondContact O-CB 3.2Å; P243-H247 PolarHBondContact O-N 3.44Å
244E91.7Very high91.5Very high65 Ų6550.9 Ų50.930%0.30423%0.227SC..Hα-helixtrans-65.6-42.7-171.8-169.761-143.100112.3R218 R240 H247 Q248R218-E244 IonicContact CZ-OE2 3.73Å; R218-E244 VanDerWaalsContact CZ-OE2 3.25Å; R218-E244 IonicContact NH1-OE2 3.3Å; R218-E244 PolarHBondContact NH1-OE2 3.5Å; R218-E244 IonicContact NH2-OE2 3.55Å; R218-E244 PolarHBondContact NH2-OE2 3.07Å; R240-E244 IonicContact CZ-OE1 3.08Å; R240-E244 IonicContact CZ-OE2 2.88Å; R240-E244 VanDerWaalsContact NH1-CD 3.34Å; R240-E244 IonicContact NH1-OE1 2.75Å; R240-E244 PolarHBondContact NH1-OE1 2.72Å; R240-E244 VanDerWaalsContact NH1-OE1 3.15Å; R240-E244 IonicContact NH1-OE2 3.9Å; R240-E244 PolarHBondContact NH1-OE2 3.43Å; R240-E244 IonicContact NH2-OE1 3.5Å; R240-E244 PolarHBondContact NH2-OE1 2.78Å; R240-E244 IonicContact NH2-OE2 2.84Å; R240-E244 PolarHBondContact NH2-OE2 3.46Å; E244-H247 WeakPolarHBondContact O-CB 3.39Å; E244-H247 PolarHBondContact O-N 3.32Å; E244-H247 IonicContact OE1-CD2 2.66Å; E244-Q248 HydrophobicContact CG-CG 4.33Å; E244-Q248 VanDerWaalsContact O-CG 3.28Å; E244-Q248 WeakPolarHBondContact O-CG 3.47Å; E244-Q248 PolarHBondContact O-N 3.06Å; E244-Q248 PolarHBondContact OE1-NE2 2.88Å
245D93.1Very high91.5Very high57 Ų5754.4 Ų54.431%0.30525%0.245SC..Hα-helixtrans-61.8-44.7177.856.3-17.5000112.1M209 K212 P243 H247 Q248 F249M209-D245 HydrophobicContact SD-CB 4.36Å; K212-D245 WeakPolarHBondContact CD-OD2 3.4Å; K212-D245 IonicContact NZ-OD2 3.48Å; K212-D245 PolarHBondContact NZ-OD2 3.13Å; P243-D245 VanDerWaalsContact CB-OD1 3.28Å; P243-D245 WeakPolarHBondContact CB-OD1 3.37Å; P243-D245 PolarHBondContact O-N 2.96Å; D245-H247 VanDerWaalsContact C-N 3.35Å; D245-H247 PolarHBondContact O-N 3.16Å; D245-Q248 PolarHBondContact O-N 3.2Å; D245-F249 VanDerWaalsContact O-CB 3.32Å; D245-F249 WeakPolarHBondContact O-CB 3.35Å; D245-F249 PolarHBondContact O-N 3.02Å
246V92.8Very high91.6Very high0 Ų057.4 Ų57.40%026%0.258CS..Hα-helixtrans-59.3-47.3173175.70000110.3M209 K212 V213 P243 Q248 F249 F250 F305M209-V246 HydrophobicContact SD-CG2 4.24Å; K212-V246 HydrophobicContact CB-CG2 3.87Å; V213-V246 HydrophobicContact CG2-CG1 3.84Å; P243-V246 HydrophobicContact CB-CB 4.19Å; P243-V246 HydrophobicContact CB-CG2 3.96Å; P243-V246 HydrophobicContact CG-CG2 4.23Å; P243-V246 PolarHBondContact O-N 3.49Å; V246-Q248 PolarHBondContact O-N 2.95Å; V246-F249 PolarHBondContact O-N 3.05Å; V246-F250 HydrophobicContact CG1-CD2 3.91Å; V246-F250 HydrophobicContact CG1-CE2 3.94Å; V246-F250 WeakPolarHBondContact O-CD2 3.48Å; V246-F250 PolarHBondContact O-N 2.97Å; V246-F250 VanDerWaalsContact O-N 3.16Å; V246-F305 HydrophobicContact CG1-CE2 3.93Å
247H93.3Very high91.5Very high17 Ų1748.6 Ų48.68%0.07923%0.226CC..Hα-helixtrans-57.5-52.4177.8174.387.8000112.1L114 R240 P243 E244 D245 F249 F250 M251L114-H247 HydrophobicContact CD1-CB 4.36Å; R240-H247 PolarHBondContact NH2-CD2 2.87Å; R240-H247 PolarHBondContact NH2-ND1 3.28Å; R240-H247 PolarHBondContact NH2-NE2 2.68Å; P243-H247 WeakPolarHBondContact O-CB 3.2Å; P243-H247 PolarHBondContact O-N 3.44Å; E244-H247 WeakPolarHBondContact O-CB 3.39Å; E244-H247 PolarHBondContact O-N 3.32Å; E244-H247 IonicContact OE1-CD2 2.66Å; D245-H247 VanDerWaalsContact C-N 3.35Å; D245-H247 PolarHBondContact O-N 3.16Å; H247-F249 VanDerWaalsContact C-N 3.28Å; H247-F249 PolarHBondContact O-N 2.81Å; H247-F250 PolarHBondContact O-N 3.46Å; H247-M251 WeakPolarHBondContact O-CB 3.39Å; H247-M251 VanDerWaalsContact O-CG 3.26Å; H247-M251 WeakPolarHBondContact O-CG 3.36Å; H247-M251 PolarHBondContact O-N 3.4Å
248Q93.9Very high91.3Very high80 Ų8044.2 Ų44.237%0.37420%0.203SC..Hα-helixtrans-63.7-34.3-179.2-66.3-58.7-30.400112.1E244 D245 V246 R252E244-Q248 HydrophobicContact CG-CG 4.33Å; E244-Q248 VanDerWaalsContact O-CG 3.28Å; E244-Q248 WeakPolarHBondContact O-CG 3.47Å; E244-Q248 PolarHBondContact O-N 3.06Å; E244-Q248 PolarHBondContact OE1-NE2 2.88Å; D245-Q248 PolarHBondContact O-N 3.2Å; V246-Q248 PolarHBondContact O-N 2.95Å; Q248-R252 VanDerWaalsContact O-CB 3.3Å; Q248-R252 WeakPolarHBondContact O-CB 3.32Å; Q248-R252 VanDerWaalsContact O-CG 3.25Å; Q248-R252 WeakPolarHBondContact O-CG 3.5Å; Q248-R252 PolarHBondContact O-N 2.92Å; Q248-R252 PolarHBondContact O-NE 2.77Å; Q248-R252 VanDerWaalsContact O-NE 3.17Å
249F92.8Very high91.1Very high22 Ų2239.8 Ų39.810%0.09620%0.199CC..Hα-helixtrans-62-56.6176.5175.8-99.5000111.8D205 F206 M209 D245 V246 H247 M251 R252 L253D205-F249 HydrophobicContact CB-CD2 4.33Å; D205-F249 HydrophobicContact CB-CE2 3.68Å; D205-F249 HydrophobicContact CB-CZ 4.37Å; F206-F249 HydrophobicContact CD1-CE1 4.09Å; F206-F249 AromaticContact CD1-CZ 3.9Å; F206-F249 HydrophobicContact CD1-CZ 3.9Å; F206-F249 AromaticContact CD2-CZ 3.99Å; F206-F249 HydrophobicContact CD2-CZ 3.99Å; F206-F249 HydrophobicContact CE1-CE1 4.23Å; F206-F249 HydrophobicContact CE1-CZ 4.03Å; F206-F249 HydrophobicContact CE2-CZ 4.11Å; F206-F249 HydrophobicContact CG-CE1 4.47Å; F206-F249 AromaticContact CG-CZ 3.9Å; F206-F249 HydrophobicContact CG-CZ 3.9Å; F206-F249 HydrophobicContact CZ-CZ 4.14Å; M209-F249 HydrophobicContact CB-CD1 3.87Å; M209-F249 HydrophobicContact CB-CE1 4.25Å; M209-F249 HydrophobicContact CB-CG 4.18Å; M209-F249 HydrophobicContact CG-CB 3.92Å; M209-F249 HydrophobicContact CG-CD1 3.88Å; M209-F249 HydrophobicContact CG-CD2 4.01Å; M209-F249 HydrophobicContact CG-CE1 4.42Å; M209-F249 HydrophobicContact CG-CG 3.66Å; M209-F249 HydrophobicContact SD-CB 4.38Å; D245-F249 VanDerWaalsContact O-CB 3.32Å; D245-F249 WeakPolarHBondContact O-CB 3.35Å; D245-F249 PolarHBondContact O-N 3.02Å; V246-F249 PolarHBondContact O-N 3.05Å; H247-F249 VanDerWaalsContact C-N 3.28Å; H247-F249 PolarHBondContact O-N 2.81Å; F249-M251 VanDerWaalsContact C-N 3.35Å; F249-M251 PolarHBondContact O-N 3.46Å; F249-R252 PolarHBondContact O-N 2.8Å; F249-L253 HydrophobicContact CE1-CD2 4.31Å; F249-L253 VanDerWaalsContact O-CB 3.29Å; F249-L253 WeakPolarHBondContact O-CB 3.25Å; F249-L253 PolarHBondContact O-N 3.17Å
250F92.3Very high90.8Very high0 Ų041.8 Ų41.80%021%0.209CC..Hα-helixtrans-68.4-33.9-176.9-76.3-79.4000112.9L114 V246 H247 L253 V254 V304 F305 Y308L114-F250 HydrophobicContact CD1-CB 3.98Å; L114-F250 HydrophobicContact CD1-CD2 4.42Å; L114-F250 HydrophobicContact CD2-CB 4.18Å; V246-F250 HydrophobicContact CG1-CD2 3.91Å; V246-F250 HydrophobicContact CG1-CE2 3.94Å; V246-F250 WeakPolarHBondContact O-CD2 3.48Å; V246-F250 PolarHBondContact O-N 2.97Å; V246-F250 VanDerWaalsContact O-N 3.16Å; H247-F250 PolarHBondContact O-N 3.46Å; F250-L253 HydrophobicContact CD1-CD2 4.21Å; F250-L253 HydrophobicContact CE1-CD2 4.5Å; F250-V254 WeakPolarHBondContact O-CB 3.19Å; F250-V254 VanDerWaalsContact O-CG2 3.23Å; F250-V254 WeakPolarHBondContact O-CG2 3.21Å; F250-V254 PolarHBondContact O-N 3.41Å; F250-V304 HydrophobicContact CD1-CG1 4.46Å; F250-F305 HydrophobicContact CD1-CB 4.21Å; F250-F305 HydrophobicContact CD1-CD2 4.32Å; F250-F305 AromaticContact CD2-CD2 3.53Å; F250-F305 HydrophobicContact CD2-CD2 3.53Å; F250-F305 HydrophobicContact CD2-CE2 4.18Å; F250-F305 HydrophobicContact CE1-CD2 4.35Å; F250-F305 AromaticContact CE2-CD2 3.59Å; F250-F305 HydrophobicContact CE2-CD2 3.59Å; F250-F305 HydrophobicContact CE2-CE2 4.02Å; F250-F305 HydrophobicContact CG-CB 4.22Å; F250-F305 AromaticContact CG-CD2 3.94Å; F250-F305 HydrophobicContact CG-CD2 3.94Å; F250-F305 HydrophobicContact CZ-CD2 4.02Å; F250-Y308 AromaticContact CE1-CD1 3.79Å; F250-Y308 HydrophobicContact CE1-CD1 3.79Å; F250-Y308 AromaticContact CE1-CG 4Å; F250-Y308 HydrophobicContact CE1-CG 4Å; F250-Y308 AromaticContact CZ-CD1 3.43Å; F250-Y308 HydrophobicContact CZ-CD1 3.43Å; F250-Y308 VanDerWaalsContact CZ-CD1 3.43Å; F250-Y308 AromaticContact CZ-CE1 3.91Å; F250-Y308 HydrophobicContact CZ-CE1 3.91Å; F250-Y308 HydrophobicContact CZ-CG 4.12Å
251M93.9Very high90.5Very high27 Ų2740.6 Ų40.613%0.13321%0.205CC..Hα-helixtrans-64.3-45.3173.5-69.8-58.9-61.100111.5L114 H247 F249 N255 A301L114-M251 HydrophobicContact CD2-SD 4.24Å; H247-M251 WeakPolarHBondContact O-CB 3.39Å; H247-M251 VanDerWaalsContact O-CG 3.26Å; H247-M251 WeakPolarHBondContact O-CG 3.36Å; H247-M251 PolarHBondContact O-N 3.4Å; F249-M251 VanDerWaalsContact C-N 3.35Å; F249-M251 PolarHBondContact O-N 3.46Å; M251-N255 PolarHBondContact O-N 2.88Å; M251-N255 PolarHBondContact O-ND2 3.29Å; M251-A301 HydrophobicContact SD-CB 3.5Å; M251-A301 VanDerWaalsContact SD-CB 3.5Å
252R92.9Very high90.3Very high145 Ų14544.1 Ų44.155%0.54722%0.221SC..Hα-helixtrans-65-48.8176.9-76.2-177-66.1-179.13.8111.8Q248 F249 V254 N255 D256Q248-R252 VanDerWaalsContact O-CB 3.3Å; Q248-R252 WeakPolarHBondContact O-CB 3.32Å; Q248-R252 VanDerWaalsContact O-CG 3.25Å; Q248-R252 WeakPolarHBondContact O-CG 3.5Å; Q248-R252 PolarHBondContact O-N 2.92Å; Q248-R252 PolarHBondContact O-NE 2.77Å; Q248-R252 VanDerWaalsContact O-NE 3.17Å; F249-R252 PolarHBondContact O-N 2.8Å; R252-V254 PolarHBondContact O-N 3.47Å; R252-V254 VanDerWaalsContact O-N 3.13Å; R252-N255 PolarHBondContact O-N 3.34Å; R252-D256 WeakPolarHBondContact O-CB 3.28Å; R252-D256 PolarHBondContact O-N 2.74Å
253L89.5Confident90.1Very high20 Ų2052 Ų5211%0.10525%0.249CC..Hα-helixtrans-47.8-47.8178.2174.263.5000112.2I194 F206 F249 F250 T257 V304I194-L253 HydrophobicContact CD1-CD1 3.59Å; I194-L253 HydrophobicContact CD1-CG 4.48Å; F206-L253 HydrophobicContact CE1-CD1 4.31Å; F206-L253 HydrophobicContact CE1-CD2 3.58Å; F206-L253 HydrophobicContact CE2-CD1 4.41Å; F206-L253 HydrophobicContact CZ-CD1 3.58Å; F206-L253 HydrophobicContact CZ-CD2 3.75Å; F206-L253 HydrophobicContact CZ-CG 4.32Å; F249-L253 HydrophobicContact CE1-CD2 4.31Å; F249-L253 VanDerWaalsContact O-CB 3.29Å; F249-L253 WeakPolarHBondContact O-CB 3.25Å; F249-L253 PolarHBondContact O-N 3.17Å; F250-L253 HydrophobicContact CD1-CD2 4.21Å; F250-L253 HydrophobicContact CE1-CD2 4.5Å; L253-T257 VanDerWaalsContact O-CB 3.28Å; L253-T257 WeakPolarHBondContact O-CB 3.5Å; L253-T257 PolarHBondContact O-N 3.2Å; L253-T257 PolarHBondContact O-OG1 2.88Å; L253-V304 HydrophobicContact CD2-CG1 4.45Å
254V90.1Very high89.7Confident0 Ų056.2 Ų56.20%027%0.268CS..Hα-helixtrans-68.9-46.2-178.5167.10000111.6F250 R252 T257 I258 M272 I297 L300 A301 V304F250-V254 WeakPolarHBondContact O-CB 3.19Å; F250-V254 VanDerWaalsContact O-CG2 3.23Å; F250-V254 WeakPolarHBondContact O-CG2 3.21Å; F250-V254 PolarHBondContact O-N 3.41Å; R252-V254 PolarHBondContact O-N 3.47Å; R252-V254 VanDerWaalsContact O-N 3.13Å; V254-T257 PolarHBondContact O-N 3.34Å; V254-I258 HydrophobicContact CG1-CD1 3.87Å; V254-I258 VanDerWaalsContact O-CG1 3.28Å; V254-I258 WeakPolarHBondContact O-CG1 3.49Å; V254-I258 PolarHBondContact O-N 2.81Å; V254-M272 HydrophobicContact CG2-CE 4.49Å; V254-I297 HydrophobicContact CG1-CD1 3.65Å; V254-I297 HydrophobicContact CG1-CG1 4.48Å; V254-L300 HydrophobicContact CB-CD2 4.42Å; V254-L300 HydrophobicContact CG1-CD2 3.36Å; V254-L300 HydrophobicContact CG2-CD2 4.21Å; V254-A301 HydrophobicContact CB-CB 4.28Å; V254-A301 HydrophobicContact CG1-CB 4.39Å; V254-A301 HydrophobicContact CG2-CB 3.96Å; V254-V304 HydrophobicContact CG2-CB 3.98Å; V254-V304 HydrophobicContact CG2-CG1 3.98Å; V254-V304 HydrophobicContact CG2-CG2 4.01Å
255N91.1Very high89.1Confident73 Ų7360 Ų6039%0.3929%0.291SS..Hα-helixtrans-60.7-46.9177.4-77.8-57.6000111.6M251 R252 T257 I258 A259 I297M251-N255 PolarHBondContact O-N 2.88Å; M251-N255 PolarHBondContact O-ND2 3.29Å; R252-N255 PolarHBondContact O-N 3.34Å; N255-T257 VanDerWaalsContact C-N 3.34Å; N255-T257 PolarHBondContact O-N 2.95Å; N255-I258 PolarHBondContact O-N 2.55Å; N255-A259 WeakPolarHBondContact O-CB 3.34Å; N255-A259 PolarHBondContact O-N 3.14Å; N255-I297 WeakPolarHBondContact OD1-CG1 3.48Å
256D89.6Confident88.2Confident106 Ų10661.2 Ų61.257%0.56729%0.293SS*.Hα-helixtrans-64.3-40.8-179.4-63.3-19.7000110.9R252 A259 L260R252-D256 WeakPolarHBondContact O-CB 3.28Å; R252-D256 PolarHBondContact O-N 2.74Å; D256-A259 PolarHBondContact O-N 3.39Å; D256-L260 VanDerWaalsContact O-CB 3.23Å; D256-L260 WeakPolarHBondContact O-CB 3.37Å; D256-L260 PolarHBondContact O-N 3.18Å
257T87.1Confident87.2Confident14 Ų1468.5 Ų68.59%0.08633%0.325CS..Hα-helixtrans-65.7-41.2177.7-57.80000112L253 V254 N255 R261 M272L253-T257 VanDerWaalsContact O-CB 3.28Å; L253-T257 WeakPolarHBondContact O-CB 3.5Å; L253-T257 PolarHBondContact O-N 3.2Å; L253-T257 PolarHBondContact O-OG1 2.88Å; V254-T257 PolarHBondContact O-N 3.34Å; N255-T257 VanDerWaalsContact C-N 3.34Å; N255-T257 PolarHBondContact O-N 2.95Å; T257-R261 WeakPolarHBondContact O-CG 3.29Å; T257-R261 PolarHBondContact O-N 3.23Å; T257-R261 VanDerWaalsContact O-N 3.14Å; T257-M272 HydrophobicContact CG2-CE 4.06Å; T257-M272 HydrophobicContact CG2-CG 3.83Å; T257-M272 HydrophobicContact CG2-SD 4.34Å
258I86.6Confident86.2Confident13 Ų1371.4 Ų71.47%0.06734%0.335CS..Hα-helixtrans-65.3-50.2176.4-69.7169.2000109.8V254 N255 L260 R261 E262 I276 I297 L300V254-I258 HydrophobicContact CG1-CD1 3.87Å; V254-I258 VanDerWaalsContact O-CG1 3.28Å; V254-I258 WeakPolarHBondContact O-CG1 3.49Å; V254-I258 PolarHBondContact O-N 2.81Å; N255-I258 PolarHBondContact O-N 2.55Å; I258-L260 VanDerWaalsContact C-N 3.29Å; I258-L260 PolarHBondContact O-N 3.34Å; I258-R261 PolarHBondContact O-N 3.49Å; I258-E262 HydrophobicContact CG2-CG 4.31Å; I258-E262 WeakPolarHBondContact O-CB 3.23Å; I258-E262 WeakPolarHBondContact O-CG 3.37Å; I258-E262 PolarHBondContact O-N 3.1Å; I258-I276 HydrophobicContact CG1-CD1 4.08Å; I258-I276 HydrophobicContact CG1-CG1 4.02Å; I258-I297 HydrophobicContact CD1-CD1 3.49Å; I258-I297 VanDerWaalsContact CD1-CD1 3.49Å; I258-L300 HydrophobicContact CD1-CD1 4.27Å; I258-L300 HydrophobicContact CD1-CD2 4.48Å
259A87.8Confident85Confident55 Ų5573 Ų7346%0.45535%0.346SS..Hα-helixtrans-58.9-41-179.900000112N255 D256 R263N255-A259 WeakPolarHBondContact O-CB 3.34Å; N255-A259 PolarHBondContact O-N 3.14Å; D256-A259 PolarHBondContact O-N 3.39Å; A259-R263 VanDerWaalsContact O-CB 3.25Å; A259-R263 WeakPolarHBondContact O-CB 3.47Å; A259-R263 PolarHBondContact O-N 2.94Å
260L85.6Confident84.4Confident67 Ų6772.6 Ų72.635%0.35135%0.345SS..Hα-helixtrans-61.4-49.6176.3-177.967000111.9D256 I258 R263 E264 F266D256-L260 VanDerWaalsContact O-CB 3.23Å; D256-L260 WeakPolarHBondContact O-CB 3.37Å; D256-L260 PolarHBondContact O-N 3.18Å; I258-L260 VanDerWaalsContact C-N 3.29Å; I258-L260 PolarHBondContact O-N 3.34Å; L260-R263 VanDerWaalsContact CD1-NH2 3.29Å; L260-R263 PolarHBondContact O-N 3.47Å; L260-E264 VanDerWaalsContact CD1-CD 3.49Å; L260-E264 HydrophobicContact CD1-CG 4.29Å; L260-E264 WeakPolarHBondContact CD1-OE1 3.43Å; L260-E264 WeakPolarHBondContact O-CB 3.26Å; L260-E264 PolarHBondContact O-N 3Å; L260-F266 HydrophobicContact CG-CE1 4.49Å
261R85.4Confident83.8Confident19 Ų1973 Ų737%0.07235%0.347CS..Hα-helixtrans-67.1-37.2-178.2-71.6178.1-172.8-148.7-0.8112.3F192 T257 I258 N265 F266 D270F192-R261 PolarHBondContact O-NH2 2.9Å; T257-R261 WeakPolarHBondContact O-CG 3.29Å; T257-R261 PolarHBondContact O-N 3.23Å; T257-R261 VanDerWaalsContact O-N 3.14Å; I258-R261 PolarHBondContact O-N 3.49Å; R261-N265 WeakPolarHBondContact O-CA 3.29Å; R261-N265 PolarHBondContact O-N 3.49Å; R261-F266 HydrophobicContact CG-CE1 4.09Å; R261-F266 HydrophobicContact CG-CE2 4.41Å; R261-F266 HydrophobicContact CG-CZ 3.9Å; R261-D270 IonicContact CZ-OD1 3.06Å; R261-D270 IonicContact CZ-OD2 3.47Å; R261-D270 IonicContact NH1-OD1 3.87Å; R261-D270 PolarHBondContact NH1-OD1 3.25Å; R261-D270 IonicContact NH1-OD2 3.16Å; R261-D270 PolarHBondContact NH1-OD2 2.94Å; R261-D270 IonicContact NH2-OD1 2.98Å; R261-D270 PolarHBondContact NH2-OD1 3.35Å; R261-D270 IonicContact NH2-OD2 3.31Å; R261-D270 PolarHBondContact NH2-OD2 3.08Å
262E83.2Confident83.3Confident117 Ų11771.7 Ų71.755%0.54734%0.341SS..Hα-helixtrans-66.2-41.5174.2-72.4178.917000111.4I258I258-E262 HydrophobicContact CG2-CG 4.31Å; I258-E262 WeakPolarHBondContact O-CB 3.23Å; I258-E262 WeakPolarHBondContact O-CG 3.37Å; I258-E262 PolarHBondContact O-N 3.1Å
263R86.6Confident82.8Confident184 Ų18465.4 Ų65.469%0.69432%0.318SS*.Hα-helixtrans-66.3-45.3178.1-175.3-17572.5-177.83.2112.8A259 L260A259-R263 VanDerWaalsContact O-CB 3.25Å; A259-R263 WeakPolarHBondContact O-CB 3.47Å; A259-R263 PolarHBondContact O-N 2.94Å; L260-R263 VanDerWaalsContact CD1-NH2 3.29Å; L260-R263 PolarHBondContact O-N 3.47Å
264E84.6Confident82.2Confident99 Ų9966.7 Ų66.746%0.46333%0.325SS..Hα-helixtrans-91-4.9-173-69.4178.9-172.200113.2L260 F266L260-E264 VanDerWaalsContact CD1-CD 3.49Å; L260-E264 HydrophobicContact CD1-CG 4.29Å; L260-E264 WeakPolarHBondContact CD1-OE1 3.43Å; L260-E264 WeakPolarHBondContact O-CB 3.26Å; L260-E264 PolarHBondContact O-N 3Å; E264-F266 HydrophobicContact CB-CD1 3.61Å; E264-F266 HydrophobicContact CB-CE1 4.07Å; E264-F266 PolarHBondContact O-N 2.76Å; E264-F266 VanDerWaalsContact O-N 3.09Å; E264-F266 WeakPolarHBondContact OE2-CE1 3.3Å
265N78.5Confident81.8Confident145 Ų14566.7 Ų66.778%0.77533%0.325SS*.THydrogen-bonded Turntrans49.335178-164.634000113.9R261R261-N265 WeakPolarHBondContact O-CA 3.29Å; R261-N265 PolarHBondContact O-N 3.49Å
266F75.6Confident81.3Confident82 Ų8263.8 Ų63.836%0.3631%0.309SS..  trans-105.5144.9175.381.5-87.7000110.8L260 R261 E264 R268L260-F266 HydrophobicContact CG-CE1 4.49Å; R261-F266 HydrophobicContact CG-CE1 4.09Å; R261-F266 HydrophobicContact CG-CE2 4.41Å; R261-F266 HydrophobicContact CG-CZ 3.9Å; E264-F266 HydrophobicContact CB-CD1 3.61Å; E264-F266 HydrophobicContact CB-CE1 4.07Å; E264-F266 PolarHBondContact O-N 2.76Å; E264-F266 VanDerWaalsContact O-N 3.09Å; E264-F266 WeakPolarHBondContact OE2-CE1 3.3Å; F266-R268 HydrophobicContact CE2-CB 4.33Å
267K71.2Confident80.8Confident153 Ų15361.4 Ų61.467%0.66529%0.294SS*.  trans-113.8127.8173.7-68.1-176.1179.2-175.30109.1
268R71.6Confident80.3Confident79 Ų7961.4 Ų61.430%0.29829%0.294SS..  trans-109.5132.3169.4-174.6171176.4162.22.9107.9T189 G193 F266 D270 N273T189-R268 PolarHBondContact O-NH2 3.22Å; G193-R268 VanDerWaalsContact C-NH1 3.32Å; G193-R268 VanDerWaalsContact CA-NH1 3.32Å; G193-R268 PolarHBondContact O-NH1 2.77Å; F266-R268 HydrophobicContact CE2-CB 4.33Å; R268-D270 WeakPolarHBondContact CB-OD2 3.25Å; R268-D270 VanDerWaalsContact CD-OD2 3.29Å; R268-D270 WeakPolarHBondContact CD-OD2 3.28Å; R268-D270 HydrophobicContact CG-CB 4.29Å; R268-D270 VanDerWaalsContact CG-OD2 3.31Å; R268-D270 WeakPolarHBondContact CG-OD2 3.11Å; R268-D270 IonicContact NE-OD2 2.84Å; R268-D270 PolarHBondContact O-N 2.96Å; R268-N273 WeakPolarHBondContact O-CB 3.42Å
269N69.8Low79.8Confident112 Ų11264.6 Ų64.660%0.59931%0.307SS*.  trans-77.263.1-178.9-73.1-39000111.5F144F144-N269 HydrophobicContact CE1-CB 3.62Å; F144-N269 HydrophobicContact CZ-CB 3.75Å
270D78.8Confident79.1Confident14 Ų1467.5 Ų67.58%0.07531%0.311CS..SBendtrans-118.3177.1-178.659.631.3000112.3R261 R268 M272 N273 L274R261-D270 IonicContact CZ-OD1 3.06Å; R261-D270 IonicContact CZ-OD2 3.47Å; R261-D270 IonicContact NH1-OD1 3.87Å; R261-D270 PolarHBondContact NH1-OD1 3.25Å; R261-D270 IonicContact NH1-OD2 3.16Å; R261-D270 PolarHBondContact NH1-OD2 2.94Å; R261-D270 IonicContact NH2-OD1 2.98Å; R261-D270 PolarHBondContact NH2-OD1 3.35Å; R261-D270 IonicContact NH2-OD2 3.31Å; R261-D270 PolarHBondContact NH2-OD2 3.08Å; R268-D270 WeakPolarHBondContact CB-OD2 3.25Å; R268-D270 VanDerWaalsContact CD-OD2 3.29Å; R268-D270 WeakPolarHBondContact CD-OD2 3.28Å; R268-D270 HydrophobicContact CG-CB 4.29Å; R268-D270 VanDerWaalsContact CG-OD2 3.31Å; R268-D270 WeakPolarHBondContact CG-OD2 3.11Å; R268-D270 IonicContact NE-OD2 2.84Å; R268-D270 PolarHBondContact O-N 2.96Å; D270-M272 VanDerWaalsContact C-N 3.31Å; D270-M272 PolarHBondContact O-N 2.9Å; D270-M272 WeakPolarHBondContact OD1-CB 3.23Å; D270-M272 PolarHBondContact OD1-N 3.15Å; D270-N273 PolarHBondContact O-N 2.74Å; D270-N273 WeakPolarHBondContact OD1-CB 3.48Å; D270-N273 PolarHBondContact OD1-N 2.73Å; D270-L274 PolarHBondContact O-N 3.37Å
271F80.1Confident78.2Confident9 Ų970.4 Ų70.44%0.03932%0.321CS..Hα-helixtrans-64.2-36.7179.3178.1-115.1000112L133 T136 A191 F192 N273 L274 L275 F307L133-F271 HydrophobicContact CD2-CE2 3.68Å; L133-F271 HydrophobicContact CD2-CZ 3.84Å; T136-F271 HydrophobicContact CG2-CB 4.47Å; T136-F271 HydrophobicContact CG2-CD2 3.57Å; T136-F271 HydrophobicContact CG2-CE2 4.26Å; T136-F271 HydrophobicContact CG2-CG 4.44Å; A191-F271 HydrophobicContact CB-CB 3.97Å; A191-F271 HydrophobicContact CB-CD1 4.38Å; A191-F271 WeakPolarHBondContact O-CA 3.44Å; A191-F271 VanDerWaalsContact O-CB 3.23Å; A191-F271 WeakPolarHBondContact O-CB 3.27Å; A191-F271 PolarHBondContact O-N 3.1Å; F192-F271 HydrophobicContact CE1-CD1 4.02Å; F271-N273 VanDerWaalsContact C-N 3.34Å; F271-N273 PolarHBondContact O-N 3.35Å; F271-L274 HydrophobicContact CD2-CD2 4.37Å; F271-L274 WeakPolarHBondContact O-CB 3.44Å; F271-L274 PolarHBondContact O-N 2.89Å; F271-L275 HydrophobicContact CD1-CD1 4.06Å; F271-L275 HydrophobicContact CD1-CG 4.46Å; F271-L275 HydrophobicContact CE1-CD1 3.6Å; F271-L275 HydrophobicContact CE1-CD2 4.35Å; F271-L275 HydrophobicContact CE1-CG 4.11Å; F271-L275 HydrophobicContact CE2-CD2 4.15Å; F271-L275 HydrophobicContact CE2-CG 4.35Å; F271-L275 HydrophobicContact CZ-CD1 3.95Å; F271-L275 HydrophobicContact CZ-CD2 3.84Å; F271-L275 HydrophobicContact CZ-CG 4.04Å; F271-L275 WeakPolarHBondContact O-CG 3.42Å; F271-L275 PolarHBondContact O-N 3.24Å; F271-L275 VanDerWaalsContact O-N 3.1Å; F271-F307 HydrophobicContact CD1-CD2 4.48Å; F271-F307 HydrophobicContact CE1-CB 4.02Å; F271-F307 AromaticContact CE1-CD2 3.34Å; F271-F307 HydrophobicContact CE1-CD2 3.34Å; F271-F307 AromaticContact CE1-CE2 3.97Å; F271-F307 HydrophobicContact CE1-CE2 3.97Å; F271-F307 AromaticContact CE1-CG 3.74Å; F271-F307 HydrophobicContact CE1-CG 3.74Å; F271-F307 HydrophobicContact CE2-CD2 4.33Å; F271-F307 HydrophobicContact CE2-CE2 4.17Å; F271-F307 HydrophobicContact CE2-CZ 4.48Å; F271-F307 AromaticContact CZ-CD2 3.25Å; F271-F307 HydrophobicContact CZ-CD2 3.25Å; F271-F307 AromaticContact CZ-CE2 3.34Å; F271-F307 HydrophobicContact CZ-CE2 3.34Å; F271-F307 AromaticContact CZ-CG 3.92Å; F271-F307 HydrophobicContact CZ-CG 3.92Å; F271-F307 HydrophobicContact CZ-CZ 4.05Å
272M83.6Confident77.1Confident0 Ų071.3 Ų71.30%034%0.337CS..Hα-helixtrans-59.7-42.3174.6-177.167.377.300112A191 F192 V254 T257 D270 L274 L275 I276 L300 V304A191-M272 PolarHBondContact O-N 3.04Å; F192-M272 HydrophobicContact CD1-CE 4.15Å; V254-M272 HydrophobicContact CG2-CE 4.49Å; T257-M272 HydrophobicContact CG2-CE 4.06Å; T257-M272 HydrophobicContact CG2-CG 3.83Å; T257-M272 HydrophobicContact CG2-SD 4.34Å; D270-M272 VanDerWaalsContact C-N 3.31Å; D270-M272 PolarHBondContact O-N 2.9Å; D270-M272 WeakPolarHBondContact OD1-CB 3.23Å; D270-M272 PolarHBondContact OD1-N 3.15Å; M272-L274 VanDerWaalsContact C-N 3.33Å; M272-L274 PolarHBondContact O-N 3.27Å; M272-L275 PolarHBondContact O-N 3.5Å; M272-L275 VanDerWaalsContact O-N 3.14Å; M272-I276 HydrophobicContact CG-CD1 3.92Å; M272-I276 HydrophobicContact CG-CG1 4.47Å; M272-I276 VanDerWaalsContact O-CG1 3.31Å; M272-I276 WeakPolarHBondContact O-CG1 3.46Å; M272-I276 PolarHBondContact O-N 2.83Å; M272-L300 HydrophobicContact SD-CD2 3.98Å; M272-V304 HydrophobicContact CE-CG1 4.29Å; M272-V304 HydrophobicContact CE-CG2 3.7Å; M272-V304 HydrophobicContact SD-CG2 4.12Å
273N82.4Confident76.2Confident13 Ų1374 Ų747%0.0734%0.342CS..Hα-helixtrans-64.4-38.9178.4-173.879.6000111.9R268 D270 F271 L275 I276 E277R268-N273 WeakPolarHBondContact O-CB 3.42Å; D270-N273 PolarHBondContact O-N 2.74Å; D270-N273 WeakPolarHBondContact OD1-CB 3.48Å; D270-N273 PolarHBondContact OD1-N 2.73Å; F271-N273 VanDerWaalsContact C-N 3.34Å; F271-N273 PolarHBondContact O-N 3.35Å; N273-L275 VanDerWaalsContact C-N 3.32Å; N273-L275 PolarHBondContact O-N 2.99Å; N273-I276 PolarHBondContact O-N 2.73Å; N273-E277 PolarHBondContact ND2-OE1 3.31Å; N273-E277 WeakPolarHBondContact O-CG 3.41Å; N273-E277 PolarHBondContact O-N 3.07Å
274L77.9Confident75.2Confident47 Ų4767 Ų6725%0.24632%0.319CS..Hα-helixtrans-58.6-46.2172175.368.9000111.3T136 D270 F271 M272 I276 E277 L278T136-L274 WeakPolarHBondContact OG1-CD2 3.5Å; D270-L274 PolarHBondContact O-N 3.37Å; F271-L274 HydrophobicContact CD2-CD2 4.37Å; F271-L274 WeakPolarHBondContact O-CB 3.44Å; F271-L274 PolarHBondContact O-N 2.89Å; M272-L274 VanDerWaalsContact C-N 3.33Å; M272-L274 PolarHBondContact O-N 3.27Å; L274-I276 VanDerWaalsContact C-N 3.32Å; L274-I276 PolarHBondContact O-N 3.15Å; L274-E277 PolarHBondContact O-N 3.15Å; L274-L278 HydrophobicContact CD1-CD1 4.37Å; L274-L278 HydrophobicContact CD1-CG 4.37Å; L274-L278 HydrophobicContact CG-CD1 4.11Å; L274-L278 HydrophobicContact CG-CG 4.5Å; L274-L278 WeakPolarHBondContact O-CB 3.47Å; L274-L278 VanDerWaalsContact O-CG 3.27Å; L274-L278 WeakPolarHBondContact O-CG 3.34Å; L274-L278 PolarHBondContact O-N 2.77Å
275L81.2Confident74.3Confident0 Ų066.8 Ų66.80%033%0.325CS..Hα-helixtrans-64.2-38.8179.5-63.3179.4000112.1L133 F271 M272 N273 L278 K279 M295 L300 Q303 V304L133-L275 HydrophobicContact CD2-CD2 3.82Å; F271-L275 HydrophobicContact CD1-CD1 4.06Å; F271-L275 HydrophobicContact CD1-CG 4.46Å; F271-L275 HydrophobicContact CE1-CD1 3.6Å; F271-L275 HydrophobicContact CE1-CD2 4.35Å; F271-L275 HydrophobicContact CE1-CG 4.11Å; F271-L275 HydrophobicContact CE2-CD2 4.15Å; F271-L275 HydrophobicContact CE2-CG 4.35Å; F271-L275 HydrophobicContact CZ-CD1 3.95Å; F271-L275 HydrophobicContact CZ-CD2 3.84Å; F271-L275 HydrophobicContact CZ-CG 4.04Å; F271-L275 WeakPolarHBondContact O-CG 3.42Å; F271-L275 PolarHBondContact O-N 3.24Å; F271-L275 VanDerWaalsContact O-N 3.1Å; M272-L275 PolarHBondContact O-N 3.5Å; M272-L275 VanDerWaalsContact O-N 3.14Å; N273-L275 VanDerWaalsContact C-N 3.32Å; N273-L275 PolarHBondContact O-N 2.99Å; L275-L278 PolarHBondContact O-N 2.72Å; L275-K279 PolarHBondContact O-N 3.3Å; L275-M295 HydrophobicContact CB-CE 4.1Å; L275-M295 HydrophobicContact CD2-CE 3.6Å; L275-M295 HydrophobicContact CD2-SD 4.43Å; L275-M295 HydrophobicContact CG-CE 4.46Å; L275-L300 HydrophobicContact CB-CD1 3.73Å; L275-L300 HydrophobicContact CB-CD2 4.32Å; L275-L300 HydrophobicContact CB-CG 3.78Å; L275-L300 HydrophobicContact CD1-CD2 4.2Å; L275-L300 HydrophobicContact CD1-CG 4.13Å; L275-Q303 HydrophobicContact CD1-CB 4.2Å; L275-Q303 HydrophobicContact CD2-CB 4.26Å; L275-Q303 HydrophobicContact CD2-CG 4.47Å; L275-V304 HydrophobicContact CD1-CG2 3.6Å
276I81.1Confident73.6Confident12 Ų1261.7 Ų61.76%0.06230%0.297CS..Hα-helixtrans-63.7-45.5175-68.4169000110.7I258 M272 N273 L274 L278 K279 Q280I258-I276 HydrophobicContact CG1-CD1 4.08Å; I258-I276 HydrophobicContact CG1-CG1 4.02Å; M272-I276 HydrophobicContact CG-CD1 3.92Å; M272-I276 HydrophobicContact CG-CG1 4.47Å; M272-I276 VanDerWaalsContact O-CG1 3.31Å; M272-I276 WeakPolarHBondContact O-CG1 3.46Å; M272-I276 PolarHBondContact O-N 2.83Å; N273-I276 PolarHBondContact O-N 2.73Å; L274-I276 VanDerWaalsContact C-N 3.32Å; L274-I276 PolarHBondContact O-N 3.15Å; I276-L278 VanDerWaalsContact C-N 3.31Å; I276-L278 PolarHBondContact O-N 2.63Å; I276-K279 WeakPolarHBondContact O-CB 3.4Å; I276-K279 PolarHBondContact O-N 2.81Å; I276-K279 VanDerWaalsContact O-N 3.14Å; I276-Q280 HydrophobicContact CG2-CG 4.3Å; I276-Q280 WeakPolarHBondContact O-CB 3.34Å; I276-Q280 WeakPolarHBondContact O-CG 3.49Å; I276-Q280 PolarHBondContact O-N 3.06Å
277E78.8Confident72.7Confident55 Ų5566.5 Ų66.526%0.25733%0.327SS..Hα-helixtrans-61.6-40.2176.1-76.3-176.7-16200112N273 L274 K279 Q280 K281N273-E277 PolarHBondContact ND2-OE1 3.31Å; N273-E277 WeakPolarHBondContact O-CG 3.41Å; N273-E277 PolarHBondContact O-N 3.07Å; L274-E277 PolarHBondContact O-N 3.15Å; E277-K279 VanDerWaalsContact C-N 3.3Å; E277-K279 PolarHBondContact O-N 2.97Å; E277-Q280 PolarHBondContact O-N 2.95Å; E277-K281 WeakPolarHBondContact O-CB 3.4Å; E277-K281 VanDerWaalsContact O-CG 3.27Å; E277-K281 WeakPolarHBondContact O-CG 3.41Å; E277-K281 PolarHBondContact O-N 3.19Å; E277-K281 IonicContact OE2-NZ 2.68Å; E277-K281 PolarHBondContact OE2-NZ 2.88Å
278L75.1Confident72.4Confident14 Ų1463.8 Ų63.87%0.07332%0.32CS..Hα-helixtrans-65.4-33.9175.4-72.4173.5000112.2R132 L274 L275 I276 V284 G294 M295R132-L278 HydrophobicContact CB-CD1 4.15Å; L274-L278 HydrophobicContact CD1-CD1 4.37Å; L274-L278 HydrophobicContact CD1-CG 4.37Å; L274-L278 HydrophobicContact CG-CD1 4.11Å; L274-L278 HydrophobicContact CG-CG 4.5Å; L274-L278 WeakPolarHBondContact O-CB 3.47Å; L274-L278 VanDerWaalsContact O-CG 3.27Å; L274-L278 WeakPolarHBondContact O-CG 3.34Å; L274-L278 PolarHBondContact O-N 2.77Å; L275-L278 PolarHBondContact O-N 2.72Å; I276-L278 VanDerWaalsContact C-N 3.31Å; I276-L278 PolarHBondContact O-N 2.63Å; L278-V284 HydrophobicContact CD2-CG2 3.89Å; L278-G294 WeakPolarHBondContact O-CA 3.45Å; L278-M295 HydrophobicContact CB-CE 3.54Å; L278-M295 HydrophobicContact CD1-CE 3.83Å; L278-M295 HydrophobicContact CG-CE 4.35Å
279K76.4Confident72.1Confident80 Ų8062.5 Ų62.535%0.34833%0.331SS..Hα-helixtrans-67.6-45171.1174.6177.9-174.8-58.80111.5L275 I276 E277 M295 L300L275-K279 PolarHBondContact O-N 3.3Å; I276-K279 WeakPolarHBondContact O-CB 3.4Å; I276-K279 PolarHBondContact O-N 2.81Å; I276-K279 VanDerWaalsContact O-N 3.14Å; E277-K279 VanDerWaalsContact C-N 3.3Å; E277-K279 PolarHBondContact O-N 2.97Å; K279-M295 WeakPolarHBondContact CG-O 3.49Å; K279-L300 HydrophobicContact CB-CD1 4.33Å; K279-L300 HydrophobicContact CD-CD1 4.37Å
280Q73.7Confident72Confident117 Ų11760.5 Ų60.555%0.54732%0.318SS..Hα-helixtrans-72.5-38.7-175.5-73.7175.4-1100113.5I276 E277 G282I276-Q280 HydrophobicContact CG2-CG 4.3Å; I276-Q280 WeakPolarHBondContact O-CB 3.34Å; I276-Q280 WeakPolarHBondContact O-CG 3.49Å; I276-Q280 PolarHBondContact O-N 3.06Å; E277-Q280 PolarHBondContact O-N 2.95Å; Q280-G282 PolarHBondContact O-N 2.88Å; Q280-G282 VanDerWaalsContact O-N 3.15Å
281K67.1Low71.5Confident127 Ų12763.9 Ų63.955%0.55234%0.339SS*.Hα-helixtrans-62-24.3-177.6-77.6170.9-178.81660112.4E277 R283 V284E277-K281 WeakPolarHBondContact O-CB 3.4Å; E277-K281 VanDerWaalsContact O-CG 3.27Å; E277-K281 WeakPolarHBondContact O-CG 3.41Å; E277-K281 PolarHBondContact O-N 3.19Å; E277-K281 IonicContact OE2-NZ 2.68Å; E277-K281 PolarHBondContact OE2-NZ 2.88Å; K281-R283 PolarHBondContact O-N 3.24Å; K281-V284 HydrophobicContact CB-CG2 4.2Å; K281-V284 HydrophobicContact CD-CG2 4.41Å
282G61.2Low70.8Confident39 Ų3963.6 Ų63.640%0.40234%0.338SS..SBendtrans67.4-32.817500000114.7Q280 E293 G294Q280-G282 PolarHBondContact O-N 2.88Å; Q280-G282 VanDerWaalsContact O-N 3.15Å; G282-E293 CarbonylContact O-C 3.43Å; G282-G294 PolarHBondContact O-N 3.27Å
283R64.5Low70.1Confident174 Ų17470.3 Ų70.366%0.65737%0.369SS*.EExtended strand (participates in β ladder)trans-145.1134.9169.7-68.3-177.6178.2160.30.3109.3K281 V291 I292K281-R283 PolarHBondContact O-N 3.24Å; R283-V291 HydrophobicContact CB-CG1 3.89Å; R283-V291 HydrophobicContact CG-CG1 4.1Å; R283-I292 CarbonylContact C-O 3.59Å; R283-I292 WeakPolarHBondContact CA-O 3.45Å
284V65.3Low69.4Low36 Ų3670.8 Ų70.822%0.21838%0.377CS..EExtended strand (participates in β ladder)trans-119.1118173.1-179.80000107.8L278 K281 I292L278-V284 HydrophobicContact CD2-CG2 3.89Å; K281-V284 HydrophobicContact CB-CG2 4.2Å; K281-V284 HydrophobicContact CD-CG2 4.41Å; V284-I292 PolarHBondContact N-O 3.41Å; V284-I292 PolarHBondContact O-N 3.08Å
285T66.6Low69.5Low94 Ų9468.9 Ų68.958%0.57737%0.367SS*.EExtended strand (participates in β ladder)trans-83.6118.8169.6-49.50000108.1E290 V291T285-E290 WeakPolarHBondContact CA-O 3.09Å; T285-V291 HydrophobicContact CG2-CG2 4.44Å
286L64.2Low69.7Low38 Ų3873.1 Ų73.120%0.19939%0.39CS..  trans-73.2162.9173.7-69.6-172.4000111.3Q131 N288 G289 E290 I292Q131-L286 HydrophobicContact CB-CD1 4.38Å; L286-N288 WeakPolarHBondContact CB-OD1 3.31Å; L286-N288 PolarHBondContact O-N 3.27Å; L286-G289 PolarHBondContact O-N 2.88Å; L286-E290 HydrophobicContact CD1-CB 4.38Å; L286-E290 PolarHBondContact N-O 3.19Å; L286-I292 HydrophobicContact CD1-CD1 3.43Å; L286-I292 VanDerWaalsContact CD1-CD1 3.43Å; L286-I292 HydrophobicContact CD1-CG1 4.34Å; L286-I292 HydrophobicContact CD2-CD1 3.85Å; L286-I292 HydrophobicContact CG-CD1 3.5Å; L286-I292 HydrophobicContact CG-CG1 4.21Å
287D57.2Low70Confident183 Ų18375.1 Ų75.198%0.97940%0.4SS*.THydrogen-bonded Turntrans-58.8-20.1176.5-58.5-28.7000113.2
288N63.7Low70.5Confident96 Ų9672.8 Ų72.851%0.51339%0.391SS..THydrogen-bonded Turntrans-89.55.8175.270.7-6.6000113.9L286 E290L286-N288 WeakPolarHBondContact CB-OD1 3.31Å; L286-N288 PolarHBondContact O-N 3.27Å; N288-E290 VanDerWaalsContact C-N 3.33Å; N288-E290 PolarHBondContact ND2-OE2 3.14Å; N288-E290 PolarHBondContact O-N 2.98Å; N288-E290 WeakPolarHBondContact OD1-CB 3.22Å; N288-E290 PolarHBondContact OD1-N 2.91Å
289G65.4Low71.2Confident53 Ų5373.6 Ų73.655%0.54639%0.394SS..SBendtrans81.9-2.3-178.600000115.5L286 V291L286-G289 PolarHBondContact O-N 2.88Å; G289-V291 PolarHBondContact O-N 2.99Å
290E67.1Low71.9Confident70 Ų7069.8 Ų69.833%0.32738%0.378SS..  trans-72.2127.8176.4-72.6-179.7139.800110.9K127 T285 L286 N288K127-E290 IonicContact NZ-OE1 2.72Å; T285-E290 WeakPolarHBondContact CA-O 3.09Å; L286-E290 HydrophobicContact CD1-CB 4.38Å; L286-E290 PolarHBondContact N-O 3.19Å; N288-E290 VanDerWaalsContact C-N 3.33Å; N288-E290 PolarHBondContact ND2-OE2 3.14Å; N288-E290 PolarHBondContact O-N 2.98Å; N288-E290 WeakPolarHBondContact OD1-CB 3.22Å; N288-E290 PolarHBondContact OD1-N 2.91Å
291V68.3Low72.8Confident84 Ų8464.2 Ų64.251%0.50935%0.352SS..EExtended strand (participates in β ladder)trans-91.3126.3174.8-1780000109.8R283 T285 G289R283-V291 HydrophobicContact CB-CG1 3.89Å; R283-V291 HydrophobicContact CG-CG1 4.1Å; T285-V291 HydrophobicContact CG2-CG2 4.44Å; G289-V291 PolarHBondContact O-N 2.99Å
292I65.9Low74.1Confident3 Ų358.2 Ų58.22%0.01533%0.326CS..EExtended strand (participates in β ladder)trans-116.8126.8-177.1-61.6-179.2000110.3D128 R283 V284 L286D128-I292 HydrophobicContact CB-CD1 4.44Å; D128-I292 HydrophobicContact CB-CG2 4.4Å; R283-I292 CarbonylContact C-O 3.59Å; R283-I292 WeakPolarHBondContact CA-O 3.45Å; V284-I292 PolarHBondContact N-O 3.41Å; V284-I292 PolarHBondContact O-N 3.08Å; L286-I292 HydrophobicContact CD1-CD1 3.43Å; L286-I292 VanDerWaalsContact CD1-CD1 3.43Å; L286-I292 HydrophobicContact CD1-CG1 4.34Å; L286-I292 HydrophobicContact CD2-CD1 3.85Å; L286-I292 HydrophobicContact CG-CD1 3.5Å; L286-I292 HydrophobicContact CG-CG1 4.21Å
293E68.3Low75.6Confident141 Ų14156.3 Ų56.366%0.65931%0.306SS*.EExtended strand (participates in β ladder)trans-67.5148.8177.5-63.3-173.7159.200113.1R132 G282R132-E293 PolarHBondContact NH1-O 3.46Å; R132-E293 PolarHBondContact NH2-O 3.02Å; G282-E293 CarbonylContact O-C 3.43Å
294G69.1Low76.9Confident23 Ų2348 Ų4824%0.23728%0.275CS..PPolyproline II helixtrans-61.9166.1177.400000113L278 G282L278-G294 WeakPolarHBondContact O-CA 3.45Å; G282-G294 PolarHBondContact O-N 3.27Å
295M78.9Confident78.2Confident8 Ų846.6 Ų46.64%0.03927%0.266CS..PPolyproline II helixtrans-89.8142.3-179.7-71.6-177-61.600112.3M129 L275 L278 K279 E299 Q303M129-M295 HydrophobicContact CE-CG 4.35Å; M129-M295 HydrophobicContact CE-SD 3.79Å; M129-M295 HydrophobicContact SD-SD 4.07Å; L275-M295 HydrophobicContact CB-CE 4.1Å; L275-M295 HydrophobicContact CD2-CE 3.6Å; L275-M295 HydrophobicContact CD2-SD 4.43Å; L275-M295 HydrophobicContact CG-CE 4.46Å; L278-M295 HydrophobicContact CB-CE 3.54Å; L278-M295 HydrophobicContact CD1-CE 3.83Å; L278-M295 HydrophobicContact CG-CE 4.35Å; K279-M295 WeakPolarHBondContact CG-O 3.49Å; M295-E299 WeakPolarHBondContact CA-OE2 3.24Å; M295-E299 HydrophobicContact CB-CB 4.2Å; M295-E299 HydrophobicContact CG-CB 4.37Å; M295-Q303 HydrophobicContact SD-CG 4.48Å
296D85.3Confident79.4Confident89 Ų8943.1 Ų43.148%0.47624%0.244SC..PPolyproline II helixtrans-77.9171.2164.376.344.2000111.9G298 E299 L300D296-G298 VanDerWaalsContact C-N 3.3Å; D296-G298 PolarHBondContact O-N 3.18Å; D296-G298 VanDerWaalsContact OD1-CA 3.26Å; D296-G298 WeakPolarHBondContact OD1-CA 3.5Å; D296-G298 PolarHBondContact OD1-N 3.2Å; D296-E299 PolarHBondContact N-OE2 3.06Å; D296-E299 PolarHBondContact O-N 2.96Å; D296-E299 PolarHBondContact OD1-N 2.87Å; D296-L300 WeakPolarHBondContact O-CB 3.43Å; D296-L300 PolarHBondContact O-N 3.23Å
297I87.4Confident80.8Confident54 Ų5442.2 Ų42.228%0.27724%0.239SC..Hα-helixtrans-64.3-34.4-178.3-168.164.6000112.7V254 N255 I258 A301V254-I297 HydrophobicContact CG1-CD1 3.65Å; V254-I297 HydrophobicContact CG1-CG1 4.48Å; N255-I297 WeakPolarHBondContact OD1-CG1 3.48Å; I258-I297 HydrophobicContact CD1-CD1 3.49Å; I258-I297 VanDerWaalsContact CD1-CD1 3.49Å; I297-A301 WeakPolarHBondContact O-CB 3.4Å; I297-A301 PolarHBondContact O-N 3.4Å
298G90.3Very high82.4Confident6 Ų633.5 Ų33.56%0.06219%0.192CC..Hα-helixtrans-70.9-41.1178.600000111.6D296 L300 A301 A302D296-G298 VanDerWaalsContact C-N 3.3Å; D296-G298 PolarHBondContact O-N 3.18Å; D296-G298 VanDerWaalsContact OD1-CA 3.26Å; D296-G298 WeakPolarHBondContact OD1-CA 3.5Å; D296-G298 PolarHBondContact OD1-N 3.2Å; G298-L300 VanDerWaalsContact C-N 3.35Å; G298-A301 PolarHBondContact O-N 3.46Å; G298-A302 WeakPolarHBondContact O-CB 3.49Å; G298-A302 PolarHBondContact O-N 3.21Å
299E89.8Confident83.6Confident31 Ų3129.7 Ų29.715%0.14517%0.172CC..Hα-helixtrans-63.9-40.8174-70.1-175.4138.100111.9Q116 M295 D296 A302 Q303Q116-E299 PolarHBondContact NE2-OE1 3.33Å; M295-E299 WeakPolarHBondContact CA-OE2 3.24Å; M295-E299 HydrophobicContact CB-CB 4.2Å; M295-E299 HydrophobicContact CG-CB 4.37Å; D296-E299 PolarHBondContact N-OE2 3.06Å; D296-E299 PolarHBondContact O-N 2.96Å; D296-E299 PolarHBondContact OD1-N 2.87Å; E299-A302 PolarHBondContact O-N 2.67Å; E299-Q303 WeakPolarHBondContact O-CG 3.18Å; E299-Q303 PolarHBondContact O-N 3.48Å; E299-Q303 VanDerWaalsContact O-N 3.09Å; E299-Q303 PolarHBondContact O-NE2 2.89Å
300L90.3Very high84.8Confident0 Ų029.4 Ų29.40%017%0.165CC..Hα-helixtrans-62.6-49.4174.7-165.2151.1000110.6V254 I258 M272 L275 K279 D296 G298 A302 Q303 V304V254-L300 HydrophobicContact CB-CD2 4.42Å; V254-L300 HydrophobicContact CG1-CD2 3.36Å; V254-L300 HydrophobicContact CG2-CD2 4.21Å; I258-L300 HydrophobicContact CD1-CD1 4.27Å; I258-L300 HydrophobicContact CD1-CD2 4.48Å; M272-L300 HydrophobicContact SD-CD2 3.98Å; L275-L300 HydrophobicContact CB-CD1 3.73Å; L275-L300 HydrophobicContact CB-CD2 4.32Å; L275-L300 HydrophobicContact CB-CG 3.78Å; L275-L300 HydrophobicContact CD1-CD2 4.2Å; L275-L300 HydrophobicContact CD1-CG 4.13Å; K279-L300 HydrophobicContact CB-CD1 4.33Å; K279-L300 HydrophobicContact CD-CD1 4.37Å; D296-L300 WeakPolarHBondContact O-CB 3.43Å; D296-L300 PolarHBondContact O-N 3.23Å; G298-L300 VanDerWaalsContact C-N 3.35Å; L300-A302 VanDerWaalsContact C-N 3.3Å; L300-A302 PolarHBondContact O-N 3.25Å; L300-Q303 PolarHBondContact O-N 2.93Å; L300-Q303 VanDerWaalsContact O-N 3.13Å; L300-V304 HydrophobicContact CD2-CG2 3.9Å; L300-V304 WeakPolarHBondContact O-CG2 3.41Å; L300-V304 PolarHBondContact O-N 3.44Å
301A92.4Very high85.8Confident0 Ų026.5 Ų26.50%015%0.154CC..Hα-helixtrans-62.1-37.2178.100000112.6L114 M251 V254 I297 G298 Q303 V304 F305L114-A301 HydrophobicContact CD2-CB 3.82Å; M251-A301 HydrophobicContact SD-CB 3.5Å; M251-A301 VanDerWaalsContact SD-CB 3.5Å; V254-A301 HydrophobicContact CB-CB 4.28Å; V254-A301 HydrophobicContact CG1-CB 4.39Å; V254-A301 HydrophobicContact CG2-CB 3.96Å; I297-A301 WeakPolarHBondContact O-CB 3.4Å; I297-A301 PolarHBondContact O-N 3.4Å; G298-A301 PolarHBondContact O-N 3.46Å; A301-Q303 VanDerWaalsContact C-N 3.34Å; A301-Q303 PolarHBondContact O-N 2.97Å; A301-V304 PolarHBondContact O-N 3.31Å; A301-F305 VanDerWaalsContact O-CB 3.22Å; A301-F305 WeakPolarHBondContact O-CB 3.25Å; A301-F305 PolarHBondContact O-N 3.17Å
302A94.2Very high86.6Confident0 Ų022.5 Ų22.50%013%0.13CC..Hα-helixtrans-61.7-40.5174.100000112.2P113 H117 G298 E299 L300 V306P113-A302 WeakPolarHBondContact O-CB 3.46Å; H117-A302 HydrophobicContact CB-CB 4.04Å; H117-A302 VanDerWaalsContact CB-O 3.23Å; H117-A302 WeakPolarHBondContact CB-O 3.3Å; G298-A302 WeakPolarHBondContact O-CB 3.49Å; G298-A302 PolarHBondContact O-N 3.21Å; E299-A302 PolarHBondContact O-N 2.67Å; L300-A302 VanDerWaalsContact C-N 3.3Å; L300-A302 PolarHBondContact O-N 3.25Å; A302-V306 PolarHBondContact O-N 3.33Å
303Q93.4Very high87.8Confident0 Ų023.1 Ų23.10%013%0.133CC..Hα-helixtrans-68.4-48.1175.7-58.4-23.3-69.100110.9Q116 M129 L133 L275 M295 E299 L300 A301 F305 V306 F307Q116-Q303 PolarHBondContact O-NE2 3.02Å; Q116-Q303 VanDerWaalsContact O-NE2 3.12Å; M129-Q303 HydrophobicContact CE-CG 4.3Å; M129-Q303 HydrophobicContact SD-CG 3.92Å; L133-Q303 HydrophobicContact CD1-CG 4.43Å; L275-Q303 HydrophobicContact CD1-CB 4.2Å; L275-Q303 HydrophobicContact CD2-CB 4.26Å; L275-Q303 HydrophobicContact CD2-CG 4.47Å; M295-Q303 HydrophobicContact SD-CG 4.48Å; E299-Q303 WeakPolarHBondContact O-CG 3.18Å; E299-Q303 PolarHBondContact O-N 3.48Å; E299-Q303 VanDerWaalsContact O-N 3.09Å; E299-Q303 PolarHBondContact O-NE2 2.89Å; L300-Q303 PolarHBondContact O-N 2.93Å; L300-Q303 VanDerWaalsContact O-N 3.13Å; A301-Q303 VanDerWaalsContact C-N 3.34Å; A301-Q303 PolarHBondContact O-N 2.97Å; Q303-F305 VanDerWaalsContact C-N 3.26Å; Q303-F305 PolarHBondContact O-N 3.15Å; Q303-V306 WeakPolarHBondContact O-CG1 3.45Å; Q303-V306 PolarHBondContact O-N 3.41Å; Q303-F307 HydrophobicContact CB-CD2 4.36Å; Q303-F307 HydrophobicContact CB-CE2 4.48Å; Q303-F307 WeakPolarHBondContact O-CD2 3.01Å; Q303-F307 PolarHBondContact O-N 2.98Å
304V91.3Very high88.9Confident0 Ų018.6 Ų18.60%011%0.114CC..Hα-helixtrans-53.8-47176.61690000111.1F192 F250 L253 V254 M272 L275 L300 A301 F307 Y308F192-V304 HydrophobicContact CD1-CG1 4.05Å; F192-V304 HydrophobicContact CD1-CG2 4.41Å; F192-V304 HydrophobicContact CE1-CB 4.1Å; F192-V304 HydrophobicContact CE1-CG1 3.67Å; F192-V304 HydrophobicContact CE1-CG2 4.08Å; F192-V304 HydrophobicContact CZ-CG1 3.97Å; F192-V304 WeakPolarHBondContact CZ-O 3.46Å; F250-V304 HydrophobicContact CD1-CG1 4.46Å; L253-V304 HydrophobicContact CD2-CG1 4.45Å; V254-V304 HydrophobicContact CG2-CB 3.98Å; V254-V304 HydrophobicContact CG2-CG1 3.98Å; V254-V304 HydrophobicContact CG2-CG2 4.01Å; M272-V304 HydrophobicContact CE-CG1 4.29Å; M272-V304 HydrophobicContact CE-CG2 3.7Å; M272-V304 HydrophobicContact SD-CG2 4.12Å; L275-V304 HydrophobicContact CD1-CG2 3.6Å; L300-V304 HydrophobicContact CD2-CG2 3.9Å; L300-V304 WeakPolarHBondContact O-CG2 3.41Å; L300-V304 PolarHBondContact O-N 3.44Å; A301-V304 PolarHBondContact O-N 3.31Å; V304-F307 PolarHBondContact O-N 3.37Å; V304-Y308 WeakPolarHBondContact O-CB 3.34Å; V304-Y308 PolarHBondContact O-N 3.45Å
305F93.1Very high90.2Very high6 Ų617.9 Ų17.93%0.02611%0.106CC..Hα-helixtrans-56.1-54.2175.8169.7-104000112.6L114 H117 V213 M242 V246 F250 A301 Q303 F307 Y308 V309L114-F305 HydrophobicContact CB-CD1 4.23Å; L114-F305 HydrophobicContact CB-CG 4.37Å; L114-F305 HydrophobicContact CD1-CB 4.48Å; L114-F305 HydrophobicContact CD1-CD2 4.11Å; L114-F305 HydrophobicContact CD1-CG 4.2Å; L114-F305 HydrophobicContact CD2-CB 4.07Å; H117-F305 AromaticContact CD2-CD1 3.88Å; V213-F305 HydrophobicContact CG1-CE2 4.33Å; V213-F305 HydrophobicContact CG1-CZ 3.85Å; V213-F305 HydrophobicContact CG2-CE2 3.57Å; V213-F305 HydrophobicContact CG2-CZ 3.93Å; M242-F305 HydrophobicContact SD-CE1 4Å; M242-F305 HydrophobicContact SD-CE2 4.25Å; M242-F305 HydrophobicContact SD-CZ 3.51Å; M242-F305 VanDerWaalsContact SD-CZ 3.51Å; V246-F305 HydrophobicContact CG1-CE2 3.93Å; F250-F305 HydrophobicContact CD1-CB 4.21Å; F250-F305 HydrophobicContact CD1-CD2 4.32Å; F250-F305 AromaticContact CD2-CD2 3.53Å; F250-F305 HydrophobicContact CD2-CD2 3.53Å; F250-F305 HydrophobicContact CD2-CE2 4.18Å; F250-F305 HydrophobicContact CE1-CD2 4.35Å; F250-F305 AromaticContact CE2-CD2 3.59Å; F250-F305 HydrophobicContact CE2-CD2 3.59Å; F250-F305 HydrophobicContact CE2-CE2 4.02Å; F250-F305 HydrophobicContact CG-CB 4.22Å; F250-F305 AromaticContact CG-CD2 3.94Å; F250-F305 HydrophobicContact CG-CD2 3.94Å; F250-F305 HydrophobicContact CZ-CD2 4.02Å; A301-F305 VanDerWaalsContact O-CB 3.22Å; A301-F305 WeakPolarHBondContact O-CB 3.25Å; A301-F305 PolarHBondContact O-N 3.17Å; Q303-F305 VanDerWaalsContact C-N 3.26Å; Q303-F305 PolarHBondContact O-N 3.15Å; F305-F307 VanDerWaalsContact C-N 3.35Å; F305-F307 PolarHBondContact O-N 3Å; F305-Y308 PolarHBondContact O-N 2.97Å; F305-V309 HydrophobicContact CD2-CG2 4.07Å; F305-V309 HydrophobicContact CE2-CG2 3.75Å; F305-V309 HydrophobicContact CZ-CG2 4.05Å; F305-V309 WeakPolarHBondContact O-CG2 3.47Å; F305-V309 PolarHBondContact O-N 3.39Å
306V93Very high90.9Very high20 Ų2017.5 Ų17.512%0.12110%0.104CC..Hα-helixtrans-67-36-175.4780000112.4H117 F119 A302 Q303 A310H117-V306 HydrophobicContact CB-CB 3.67Å; H117-V306 HydrophobicContact CB-CG1 3.76Å; H117-V306 HydrophobicContact CB-CG2 4.25Å; F119-V306 HydrophobicContact CB-CG2 4.13Å; A302-V306 PolarHBondContact O-N 3.33Å; Q303-V306 WeakPolarHBondContact O-CG1 3.45Å; Q303-V306 PolarHBondContact O-N 3.41Å; V306-A310 WeakPolarHBondContact O-CB 3.46Å; V306-A310 PolarHBondContact O-N 3.33Å
307F92.3Very high91.4Very high19 Ų1913.4 Ų13.48%0.0838%0.082CC..Hα-helixtrans-72.6-35.3178.9-80.7-75.1000112.3L118 L133 F137 F192 F271 Q303 V304 F305 G311 I452L118-F307 HydrophobicContact CD2-CZ 4.42Å; L133-F307 HydrophobicContact CD1-CE2 3.8Å; L133-F307 HydrophobicContact CD1-CZ 4.04Å; F137-F307 HydrophobicContact CE1-CE1 4.29Å; F137-F307 HydrophobicContact CE2-CD1 4.28Å; F137-F307 AromaticContact CE2-CE1 3.39Å; F137-F307 HydrophobicContact CE2-CE1 3.39Å; F137-F307 AromaticContact CE2-CZ 3.77Å; F137-F307 HydrophobicContact CE2-CZ 3.77Å; F137-F307 AromaticContact CZ-CD1 3.67Å; F137-F307 HydrophobicContact CZ-CD1 3.67Å; F137-F307 AromaticContact CZ-CE1 3.19Å; F137-F307 HydrophobicContact CZ-CE1 3.19Å; F137-F307 HydrophobicContact CZ-CZ 4.02Å; F192-F307 HydrophobicContact CZ-CB 4.41Å; F271-F307 HydrophobicContact CD1-CD2 4.48Å; F271-F307 HydrophobicContact CE1-CB 4.02Å; F271-F307 AromaticContact CE1-CD2 3.34Å; F271-F307 HydrophobicContact CE1-CD2 3.34Å; F271-F307 AromaticContact CE1-CE2 3.97Å; F271-F307 HydrophobicContact CE1-CE2 3.97Å; F271-F307 AromaticContact CE1-CG 3.74Å; F271-F307 HydrophobicContact CE1-CG 3.74Å; F271-F307 HydrophobicContact CE2-CD2 4.33Å; F271-F307 HydrophobicContact CE2-CE2 4.17Å; F271-F307 HydrophobicContact CE2-CZ 4.48Å; F271-F307 AromaticContact CZ-CD2 3.25Å; F271-F307 HydrophobicContact CZ-CD2 3.25Å; F271-F307 AromaticContact CZ-CE2 3.34Å; F271-F307 HydrophobicContact CZ-CE2 3.34Å; F271-F307 AromaticContact CZ-CG 3.92Å; F271-F307 HydrophobicContact CZ-CG 3.92Å; F271-F307 HydrophobicContact CZ-CZ 4.05Å; Q303-F307 HydrophobicContact CB-CD2 4.36Å; Q303-F307 HydrophobicContact CB-CE2 4.48Å; Q303-F307 WeakPolarHBondContact O-CD2 3.01Å; Q303-F307 PolarHBondContact O-N 2.98Å; V304-F307 PolarHBondContact O-N 3.37Å; F305-F307 VanDerWaalsContact C-N 3.35Å; F305-F307 PolarHBondContact O-N 3Å; F307-G311 PolarHBondContact O-N 3.06Å; F307-I452 HydrophobicContact CE1-CG2 3.64Å; F307-I452 HydrophobicContact CZ-CG2 3.88Å
308Y91Very high91.9Very high0 Ų011.4 Ų11.40%07%0.073CC..Hα-helixtrans-59.5-58.7170.4176.9-102.2000110.2T184 I187 F192 F206 F250 V304 F305 A310 G311 F312T184-Y308 HydrophobicContact CG2-CE2 4.1Å; I187-Y308 HydrophobicContact CG2-CD2 3.77Å; I187-Y308 HydrophobicContact CG2-CE2 4.05Å; F192-Y308 AromaticContact CE2-CD2 3.99Å; F192-Y308 HydrophobicContact CE2-CD2 3.99Å; F192-Y308 HydrophobicContact CE2-CG 4.36Å; F206-Y308 HydrophobicContact CD1-CD2 4.37Å; F206-Y308 AromaticContact CD1-CE2 3.81Å; F206-Y308 HydrophobicContact CD1-CE2 3.81Å; F206-Y308 PolarHBondContact O-OH 3.23Å; F250-Y308 AromaticContact CE1-CD1 3.79Å; F250-Y308 HydrophobicContact CE1-CD1 3.79Å; F250-Y308 AromaticContact CE1-CG 4Å; F250-Y308 HydrophobicContact CE1-CG 4Å; F250-Y308 AromaticContact CZ-CD1 3.43Å; F250-Y308 HydrophobicContact CZ-CD1 3.43Å; F250-Y308 VanDerWaalsContact CZ-CD1 3.43Å; F250-Y308 AromaticContact CZ-CE1 3.91Å; F250-Y308 HydrophobicContact CZ-CE1 3.91Å; F250-Y308 HydrophobicContact CZ-CG 4.12Å; V304-Y308 WeakPolarHBondContact O-CB 3.34Å; V304-Y308 PolarHBondContact O-N 3.45Å; F305-Y308 PolarHBondContact O-N 2.97Å; Y308-A310 PolarHBondContact O-N 3.16Å; Y308-G311 PolarHBondContact O-N 3.49Å; Y308-G311 VanDerWaalsContact O-N 3.16Å; Y308-F312 AromaticContact CD1-CD1 3.99Å; Y308-F312 HydrophobicContact CD1-CD1 3.99Å; Y308-F312 HydrophobicContact CD1-CE1 4.09Å; Y308-F312 AromaticContact CE1-CD1 3.68Å; Y308-F312 HydrophobicContact CE1-CD1 3.68Å; Y308-F312 AromaticContact CE1-CE1 3.68Å; Y308-F312 HydrophobicContact CE1-CE1 3.68Å; Y308-F312 HydrophobicContact CE2-CD1 4.46Å; Y308-F312 AromaticContact CZ-CD1 3.91Å; Y308-F312 VanDerWaalsContact O-CD1 3.27Å; Y308-F312 WeakPolarHBondContact O-CD1 3.18Å; Y308-F312 PolarHBondContact O-N 3.2Å; Y308-F312 VanDerWaalsContact O-N 3.13Å
309V90Very high92.3Very high16 Ų1611.1 Ų11.110%0.0977%0.07CC..Hα-helixtrans-60.3-45.8-175.21730000112.3V213 F214 F305 G311 F312 E313V213-V309 HydrophobicContact CB-CG2 4.39Å; V213-V309 HydrophobicContact CG1-CG1 3.97Å; V213-V309 HydrophobicContact CG1-CG2 4.14Å; V213-V309 HydrophobicContact CG2-CG2 4.02Å; F214-V309 HydrophobicContact CE1-CG1 4.19Å; F214-V309 HydrophobicContact CE2-CG1 3.59Å; F214-V309 HydrophobicContact CZ-CG1 3.27Å; F305-V309 HydrophobicContact CD2-CG2 4.07Å; F305-V309 HydrophobicContact CE2-CG2 3.75Å; F305-V309 HydrophobicContact CZ-CG2 4.05Å; F305-V309 WeakPolarHBondContact O-CG2 3.47Å; F305-V309 PolarHBondContact O-N 3.39Å; V309-G311 VanDerWaalsContact C-N 3.34Å; V309-G311 PolarHBondContact O-N 2.99Å; V309-F312 HydrophobicContact CB-CE1 4.5Å; V309-F312 HydrophobicContact CG2-CE1 4.47Å; V309-E313 PolarHBondContact O-N 3.23Å
310A90.8Very high92.7Very high48 Ų489.7 Ų9.740%0.3976%0.063SC..Hα-helixtrans-68-34.5178.700000112.3V306 Y308 T314V306-A310 WeakPolarHBondContact O-CB 3.46Å; V306-A310 PolarHBondContact O-N 3.33Å; Y308-A310 PolarHBondContact O-N 3.16Å; A310-T314 PolarHBondContact O-OG1 3.19Å
311G86.5Confident93.1Very high9 Ų99.8 Ų9.89%0.0936%0.064CC..Hα-helixtrans-73-36.6-17600000114.2F307 Y308 V309 Q460F307-G311 PolarHBondContact O-N 3.06Å; Y308-G311 PolarHBondContact O-N 3.49Å; Y308-G311 VanDerWaalsContact O-N 3.16Å; V309-G311 VanDerWaalsContact C-N 3.34Å; V309-G311 PolarHBondContact O-N 2.99Å; G311-Q460 PolarHBondContact O-NE2 2.64Å
312F86.2Confident93.4Very high0 Ų09.8 Ų9.80%06%0.064CC..Hα-helixtrans-87.8-56.1-176.290.7-98.9000113T183 I187 G210 F214 Y308 V309 T314 S316T183-F312 PolarHBondContact OG1-O 3.05Å; T183-F312 VanDerWaalsContact OG1-O 3.06Å; I187-F312 HydrophobicContact CG2-CB 4.42Å; G210-F312 WeakPolarHBondContact O-CZ 3.47Å; F214-F312 HydrophobicContact CD2-CZ 4.19Å; F214-F312 HydrophobicContact CE2-CE1 4.13Å; F214-F312 HydrophobicContact CE2-CE2 4.47Å; F214-F312 AromaticContact CE2-CZ 3.66Å; F214-F312 HydrophobicContact CE2-CZ 3.66Å; Y308-F312 AromaticContact CD1-CD1 3.99Å; Y308-F312 HydrophobicContact CD1-CD1 3.99Å; Y308-F312 HydrophobicContact CD1-CE1 4.09Å; Y308-F312 AromaticContact CE1-CD1 3.68Å; Y308-F312 HydrophobicContact CE1-CD1 3.68Å; Y308-F312 AromaticContact CE1-CE1 3.68Å; Y308-F312 HydrophobicContact CE1-CE1 3.68Å; Y308-F312 HydrophobicContact CE2-CD1 4.46Å; Y308-F312 AromaticContact CZ-CD1 3.91Å; Y308-F312 VanDerWaalsContact O-CD1 3.27Å; Y308-F312 WeakPolarHBondContact O-CD1 3.18Å; Y308-F312 PolarHBondContact O-N 3.2Å; Y308-F312 VanDerWaalsContact O-N 3.13Å; V309-F312 HydrophobicContact CB-CE1 4.5Å; V309-F312 HydrophobicContact CG2-CE1 4.47Å; F312-T314 PolarHBondContact O-N 3.15Å; F312-S316 VanDerWaalsContact O-CB 3.31Å; F312-S316 WeakPolarHBondContact O-CB 3.42Å; F312-S316 PolarHBondContact O-N 3.22Å; F312-S316 PolarHBondContact O-OG 3.01Å
313E89.5Confident93.6Very high16 Ų169.9 Ų9.98%0.0756%0.064CC..Hα-helixtrans-69.7-40.2-166.9-175.665.1-164.500112.1F214 V309 S316 S317 V492F214-E313 HydrophobicContact CD2-CB 4.38Å; F214-E313 HydrophobicContact CD2-CG 4.12Å; F214-E313 HydrophobicContact CE1-CB 4.43Å; F214-E313 HydrophobicContact CE1-CG 4.13Å; F214-E313 HydrophobicContact CE2-CB 3.52Å; F214-E313 HydrophobicContact CE2-CG 3.68Å; F214-E313 HydrophobicContact CZ-CB 3.53Å; F214-E313 HydrophobicContact CZ-CG 3.67Å; V309-E313 PolarHBondContact O-N 3.23Å; E313-S316 WeakPolarHBondContact CA-OG 3.45Å; E313-S316 PolarHBondContact O-OG 3.22Å; E313-S317 VanDerWaalsContact O-CB 3.31Å; E313-S317 WeakPolarHBondContact O-CB 3.33Å; E313-S317 PolarHBondContact O-N 2.69Å; E313-S317 VanDerWaalsContact O-N 3.09Å; E313-S317 PolarHBondContact O-OG 3.04Å; E313-V492 HydrophobicContact CG-CG2 4.26Å
314T93.1Very high93.9Very high45 Ų4510.1 Ų10.128%0.2767%0.065SC..Hα-helixtrans-70.3-44.2-175.864.60000112A310 F312 T318 L375A310-T314 PolarHBondContact O-OG1 3.19Å; F312-T314 PolarHBondContact O-N 3.15Å; T314-T318 PolarHBondContact O-N 3.05Å; T314-T318 PolarHBondContact O-OG1 3.43Å; T314-L375 WeakPolarHBondContact O-CD1 3.44Å
315S94.9Very high94.2Very high8 Ų811 Ų116%0.0567%0.069CC..Hα-helixtrans-76.9-34.4-176.3-630000111.6T318 M319 Q460S315-T318 PolarHBondContact O-N 2.68Å; S315-M319 WeakPolarHBondContact O-CE 3.39Å; S315-M319 PolarHBondContact O-N 3.39Å; S315-Q460 VanDerWaalsContact CB-CD 3.47Å; S315-Q460 PolarHBondContact OG-NE2 3.35Å
316S95.1Very high94.5Very high1 Ų110.8 Ų10.81%0.0077%0.068CC..Hα-helixtrans-63.4-45.4172.652.80000111.8M179 T183 F312 E313 T318 M319 S320M179-S316 VanDerWaalsContact C-CB 3.46Å; M179-S316 WeakPolarHBondContact O-CB 3.32Å; T183-S316 WeakPolarHBondContact OG1-CB 3.43Å; F312-S316 VanDerWaalsContact O-CB 3.31Å; F312-S316 WeakPolarHBondContact O-CB 3.42Å; F312-S316 PolarHBondContact O-N 3.22Å; F312-S316 PolarHBondContact O-OG 3.01Å; E313-S316 WeakPolarHBondContact CA-OG 3.45Å; E313-S316 PolarHBondContact O-OG 3.22Å; S316-T318 PolarHBondContact O-N 2.85Å; S316-M319 PolarHBondContact O-N 3.43Å; S316-S320 WeakPolarHBondContact O-CB 3.34Å; S316-S320 PolarHBondContact O-N 3.29Å; S316-S320 PolarHBondContact O-OG 2.96Å
317S95.8Very high94.8Very high2 Ų210 Ų101%0.0146%0.064CC..Hα-helixtrans-60.5-45.1175.7-62.50000111.6E313 M319 S320 Y321E313-S317 VanDerWaalsContact O-CB 3.31Å; E313-S317 WeakPolarHBondContact O-CB 3.33Å; E313-S317 PolarHBondContact O-N 2.69Å; E313-S317 VanDerWaalsContact O-N 3.09Å; E313-S317 PolarHBondContact O-OG 3.04Å; S317-M319 PolarHBondContact O-N 2.97Å; S317-S320 PolarHBondContact O-N 2.86Å; S317-Y321 WeakPolarHBondContact O-CD2 2.98Å; S317-Y321 PolarHBondContact O-N 3.46Å
318T97.8Very high95.1Very high12 Ų1212.3 Ų12.37%0.0748%0.075CC..Hα-helixtrans-57.6-50177.6-56.50000111.7T314 S315 S316 S320 Y321 C322 L370 L375T314-T318 PolarHBondContact O-N 3.05Å; T314-T318 PolarHBondContact O-OG1 3.43Å; S315-T318 PolarHBondContact O-N 2.68Å; S316-T318 PolarHBondContact O-N 2.85Å; T318-S320 VanDerWaalsContact C-N 3.3Å; T318-S320 PolarHBondContact O-N 3.38Å; T318-Y321 PolarHBondContact O-N 3.13Å; T318-C322 WeakPolarHBondContact O-CB 3.49Å; T318-C322 PolarHBondContact O-N 2.98Å; T318-L370 HydrophobicContact CG2-CD2 3.71Å; T318-L370 HydrophobicContact CG2-CG 3.98Å; T318-L375 WeakPolarHBondContact OG1-CD1 3.31Å
319M98.4Very high95.4Very high0 Ų014.4 Ų14.40%09%0.086CC..Hα-helixtrans-64.4-37.6178.6-71.2-175.4-72.800111.8M179 F182 T183 S315 S316 S317 C322 L323 A461 L465M179-M319 HydrophobicContact CB-CE 4.46Å; M179-M319 HydrophobicContact CG-CB 3.84Å; M179-M319 HydrophobicContact SD-CB 3.79Å; M179-M319 HydrophobicContact SD-CE 4.27Å; M179-M319 HydrophobicContact SD-SD 4.2Å; F182-M319 HydrophobicContact CD1-CE 3.65Å; F182-M319 HydrophobicContact CD1-SD 4.19Å; F182-M319 HydrophobicContact CE1-CE 3.87Å; F182-M319 HydrophobicContact CE1-SD 3.97Å; T183-M319 HydrophobicContact CG2-CE 3.28Å; S315-M319 WeakPolarHBondContact O-CE 3.39Å; S315-M319 PolarHBondContact O-N 3.39Å; S316-M319 PolarHBondContact O-N 3.43Å; S317-M319 PolarHBondContact O-N 2.97Å; M319-C322 PolarHBondContact O-N 3.48Å; M319-L323 WeakPolarHBondContact O-CB 3.29Å; M319-L323 VanDerWaalsContact O-CG 3.27Å; M319-L323 WeakPolarHBondContact O-CG 3.4Å; M319-L323 PolarHBondContact O-N 2.99Å; M319-A461 HydrophobicContact CG-CB 4.09Å; M319-L465 HydrophobicContact CB-CD2 4.32Å; M319-L465 HydrophobicContact CB-CG 4.49Å; M319-L465 HydrophobicContact CG-CD1 4.36Å; M319-L465 HydrophobicContact CG-CD2 4.4Å; M319-L465 HydrophobicContact CG-CG 4.04Å
320S98.3Very high95.8Very high1 Ų116.1 Ų16.11%0.0079%0.093CC..Hα-helixtrans-66.1-43.4179.7-52.40000112.1K176 M179 S316 S317 T318 L323 Y324K176-S320 WeakPolarHBondContact CA-OG 3.5Å; M179-S320 WeakPolarHBondContact CG-OG 3.01Å; S316-S320 WeakPolarHBondContact O-CB 3.34Å; S316-S320 PolarHBondContact O-N 3.29Å; S316-S320 PolarHBondContact O-OG 2.96Å; S317-S320 PolarHBondContact O-N 2.86Å; T318-S320 VanDerWaalsContact C-N 3.3Å; T318-S320 PolarHBondContact O-N 3.38Å; S320-L323 PolarHBondContact O-N 2.78Å; S320-Y324 WeakPolarHBondContact O-CB 3.32Å; S320-Y324 PolarHBondContact O-N 3.3Å
321Y98.6Very high96.2Very high3 Ų319.1 Ų19.11%0.01210%0.103CC..Hα-helixtrans-67.4-38.1174.9-65.5-48.3000112.1S317 T318 Y324 E325 Y373 L375 L484 Y486 L493 T495 I499S317-Y321 WeakPolarHBondContact O-CD2 2.98Å; S317-Y321 PolarHBondContact O-N 3.46Å; T318-Y321 PolarHBondContact O-N 3.13Å; Y321-Y324 WeakPolarHBondContact O-CB 3.34Å; Y321-Y324 PolarHBondContact O-N 2.84Å; Y321-E325 WeakPolarHBondContact O-CG 3.31Å; Y321-E325 PolarHBondContact O-N 2.76Å; Y321-Y373 AromaticContact CD1-CD1 3.52Å; Y321-Y373 HydrophobicContact CD1-CD1 3.52Å; Y321-Y373 AromaticContact CD1-CE1 3.63Å; Y321-Y373 HydrophobicContact CD1-CE1 3.63Å; Y321-Y373 HydrophobicContact CD1-CG 4.07Å; Y321-Y373 AromaticContact CD2-CD1 3.88Å; Y321-Y373 HydrophobicContact CD2-CD1 3.88Å; Y321-Y373 AromaticContact CD2-CG 3.79Å; Y321-Y373 HydrophobicContact CD2-CG 3.79Å; Y321-Y373 AromaticContact CE1-CD1 3.9Å; Y321-Y373 HydrophobicContact CE1-CD1 3.9Å; Y321-Y373 HydrophobicContact CE1-CE1 4.13Å; Y321-Y373 HydrophobicContact CE2-CD1 4.22Å; Y321-Y373 HydrophobicContact CE2-CG 4.45Å; Y321-Y373 AromaticContact CG-CD1 3.53Å; Y321-Y373 HydrophobicContact CG-CD1 3.53Å; Y321-Y373 HydrophobicContact CG-CD2 4.13Å; Y321-Y373 HydrophobicContact CG-CE1 4Å; Y321-Y373 AromaticContact CG-CG 3.58Å; Y321-Y373 HydrophobicContact CG-CG 3.58Å; Y321-L375 HydrophobicContact CD2-CD2 4.1Å; Y321-L375 HydrophobicContact CE2-CD2 3.63Å; Y321-L484 HydrophobicContact CD1-CD1 3.86Å; Y321-L484 HydrophobicContact CE1-CD1 3.83Å; Y321-Y486 HydrophobicContact CE1-CE1 4.12Å; Y321-L493 PolarHBondContact OH-O 3.26Å; Y321-T495 HydrophobicContact CE1-CG2 3.72Å; Y321-I499 HydrophobicContact CD1-CD1 3.88Å; Y321-I499 HydrophobicContact CE1-CD1 3.99Å
322C98.8Very high96.8Very high0 Ų019.3 Ų19.30%010%0.101CC..Hα-helixtrans-60-48.6174.2-178.10000111T318 M319 Y324 E325 L326 T369 L465T318-C322 WeakPolarHBondContact O-CB 3.49Å; T318-C322 PolarHBondContact O-N 2.98Å; M319-C322 PolarHBondContact O-N 3.48Å; C322-Y324 VanDerWaalsContact C-N 3.32Å; C322-Y324 PolarHBondContact O-N 2.81Å; C322-E325 PolarHBondContact O-N 2.94Å; C322-L326 WeakPolarHBondContact O-CB 3.11Å; C322-L326 VanDerWaalsContact O-CG 3.27Å; C322-L326 WeakPolarHBondContact O-CG 3.14Å; C322-L326 PolarHBondContact O-N 2.71Å; C322-T369 HydrophobicContact CB-CG2 3.9Å; C322-L465 HydrophobicContact CB-CD1 4.07Å; C322-L465 HydrophobicContact CB-CD2 4Å
323L98.8Very high97.4Very high1 Ų119.3 Ų19.31%0.00510%0.101CC..Hα-helixtrans-64.3-36.1177.7-68.5169.3000112.5I175 M179 M319 S320 A327 L465 I468 I469 V474 L501I175-L323 HydrophobicContact CG2-CB 4.18Å; I175-L323 HydrophobicContact CG2-CD1 3.48Å; I175-L323 VanDerWaalsContact CG2-CD1 3.48Å; I175-L323 HydrophobicContact CG2-CG 4.48Å; M179-L323 HydrophobicContact CE-CD1 4.36Å; M179-L323 HydrophobicContact SD-CD1 4.04Å; M319-L323 WeakPolarHBondContact O-CB 3.29Å; M319-L323 VanDerWaalsContact O-CG 3.27Å; M319-L323 WeakPolarHBondContact O-CG 3.4Å; M319-L323 PolarHBondContact O-N 2.99Å; S320-L323 PolarHBondContact O-N 2.78Å; L323-A327 VanDerWaalsContact O-CB 3.3Å; L323-A327 WeakPolarHBondContact O-CB 3.39Å; L323-A327 PolarHBondContact O-N 3.48Å; L323-L465 HydrophobicContact CD1-CD2 4.46Å; L323-L465 HydrophobicContact CD2-CD2 3.85Å; L323-L465 HydrophobicContact CG-CD2 3.8Å; L323-I468 HydrophobicContact CD1-CD1 3.71Å; L323-I468 HydrophobicContact CD2-CD1 4.35Å; L323-I468 HydrophobicContact CD2-CG2 4.02Å; L323-I469 HydrophobicContact CD2-CD1 3.94Å; L323-V474 HydrophobicContact CD2-CG2 4.24Å; L323-L501 HydrophobicContact CB-CD1 4.06Å; L323-L501 WeakPolarHBondContact O-CD1 3.3Å
324Y98.7Very high97.8Very high6 Ų621 Ų212%0.02411%0.111CC..Hα-helixtrans-60.9-46.2172.8171.9-95.9000111.6S320 Y321 C322 A327 Q328 Y373 T480 I482 L484 I499S320-Y324 WeakPolarHBondContact O-CB 3.32Å; S320-Y324 PolarHBondContact O-N 3.3Å; Y321-Y324 WeakPolarHBondContact O-CB 3.34Å; Y321-Y324 PolarHBondContact O-N 2.84Å; C322-Y324 VanDerWaalsContact C-N 3.32Å; C322-Y324 PolarHBondContact O-N 2.81Å; Y324-A327 PolarHBondContact O-N 3.32Å; Y324-Q328 PolarHBondContact O-N 3.14Å; Y324-Q328 PolarHBondContact OH-OE1 2.95Å; Y324-Y373 VanDerWaalsContact CD1-OH 3.24Å; Y324-Y373 WeakPolarHBondContact CD1-OH 3.41Å; Y324-Y373 VanDerWaalsContact CE1-OH 3.28Å; Y324-Y373 WeakPolarHBondContact CE1-OH 3.32Å; Y324-T480 HydrophobicContact CD2-CG2 4.2Å; Y324-T480 HydrophobicContact CE2-CG2 3.98Å; Y324-I482 HydrophobicContact CE2-CG1 4.34Å; Y324-L484 HydrophobicContact CD1-CD1 3.83Å; Y324-L484 HydrophobicContact CD1-CG 4.39Å; Y324-L484 HydrophobicContact CD2-CD1 4.11Å; Y324-L484 HydrophobicContact CD2-CD2 4.06Å; Y324-L484 HydrophobicContact CD2-CG 4.16Å; Y324-L484 HydrophobicContact CE1-CD1 3.87Å; Y324-L484 HydrophobicContact CE1-CG 4.01Å; Y324-L484 HydrophobicContact CE2-CD1 4.13Å; Y324-L484 HydrophobicContact CE2-CD2 3.79Å; Y324-L484 HydrophobicContact CE2-CG 3.73Å; Y324-L484 HydrophobicContact CG-CD1 3.97Å; Y324-L484 HydrophobicContact CG-CG 4.48Å; Y324-I499 HydrophobicContact CD2-CG2 4.13Å
325E98.7Very high98.1Very high19 Ų1924.6 Ų24.69%0.08912%0.119CC..Hα-helixtrans-67.7-41.8177.1-70.6-69.2-169.300112.7Y321 C322 A327 Q328 N329 Y373 F423Y321-E325 WeakPolarHBondContact O-CG 3.31Å; Y321-E325 PolarHBondContact O-N 2.76Å; C322-E325 PolarHBondContact O-N 2.94Å; E325-A327 PolarHBondContact O-N 2.99Å; E325-Q328 PolarHBondContact O-N 3.21Å; E325-Q328 VanDerWaalsContact O-N 3.15Å; E325-Q328 PolarHBondContact OE2-NE2 3.09Å; E325-N329 WeakPolarHBondContact O-CB 3.46Å; E325-N329 PolarHBondContact O-N 2.93Å; E325-N329 PolarHBondContact O-ND2 2.89Å; E325-Y373 HydrophobicContact CG-CE2 3.57Å; E325-Y373 VanDerWaalsContact OE1-CE2 3.28Å; E325-Y373 WeakPolarHBondContact OE1-CE2 3.18Å; E325-Y373 PolarHBondContact OE1-OH 3.37Å; E325-F423 HydrophobicContact CB-CD1 4.24Å; E325-F423 HydrophobicContact CB-CD2 3.67Å; E325-F423 HydrophobicContact CB-CE1 4.23Å; E325-F423 HydrophobicContact CB-CE2 3.7Å; E325-F423 HydrophobicContact CB-CG 4Å; E325-F423 HydrophobicContact CB-CZ 3.99Å; E325-F423 HydrophobicContact CG-CD2 3.48Å; E325-F423 VanDerWaalsContact CG-CD2 3.48Å; E325-F423 HydrophobicContact CG-CE2 3.77Å; E325-F423 HydrophobicContact CG-CG 4.11Å
326L98.8Very high98.2Very high0 Ų024.2 Ų24.20%012%0.117CC..Hα-helixtrans-62.8-32.2174.7-70179.1000112.3C322 Q328 N329 Q330 I332 Q333 L336 V365 I469C322-L326 WeakPolarHBondContact O-CB 3.11Å; C322-L326 VanDerWaalsContact O-CG 3.27Å; C322-L326 WeakPolarHBondContact O-CG 3.14Å; C322-L326 PolarHBondContact O-N 2.71Å; L326-Q328 VanDerWaalsContact C-N 3.33Å; L326-N329 CarbonylContact O-C 3.56Å; L326-N329 PolarHBondContact O-N 3.01Å; L326-Q330 PolarHBondContact O-NE2 3.38Å; L326-I332 HydrophobicContact CD2-CB 4.46Å; L326-I332 HydrophobicContact CD2-CG2 3.81Å; L326-Q333 HydrophobicContact CB-CB 4.24Å; L326-Q333 HydrophobicContact CB-CG 4.19Å; L326-Q333 HydrophobicContact CD2-CB 4.2Å; L326-Q333 PolarHBondContact O-NE2 3.03Å; L326-L336 HydrophobicContact CD1-CD2 3.76Å; L326-L336 HydrophobicContact CD2-CD2 4.23Å; L326-V365 HydrophobicContact CD1-CG1 4.46Å; L326-V365 HydrophobicContact CD2-CG1 4Å; L326-V365 HydrophobicContact CG-CG1 4.37Å; L326-I469 HydrophobicContact CD1-CD1 3.8Å; L326-I469 HydrophobicContact CD1-CG1 4.05Å
327A98.5Very high98.4Very high4 Ų424.7 Ų24.73%0.03312%0.118CC..Hα-helixtrans-68.1-34.2175.600000112.4L323 Y324 E325 Q330 V474 L476 L501L323-A327 VanDerWaalsContact O-CB 3.3Å; L323-A327 WeakPolarHBondContact O-CB 3.39Å; L323-A327 PolarHBondContact O-N 3.48Å; Y324-A327 PolarHBondContact O-N 3.32Å; E325-A327 PolarHBondContact O-N 2.99Å; A327-Q330 PolarHBondContact O-NE2 2.9Å; A327-V474 HydrophobicContact CB-CG1 4.24Å; A327-L476 HydrophobicContact CB-CD2 3.99Å; A327-L501 HydrophobicContact CB-CD1 4.05Å; A327-L501 HydrophobicContact CB-CD2 3.78Å; A327-L501 HydrophobicContact CB-CG 4.5Å
328Q98.2Very high98.5Very high67 Ų6729 Ų2931%0.31314%0.141SC..Hα-helixtrans-77.9-28.6174.5-64.7179.4111.400112.7Y324 E325 L326 L476Y324-Q328 PolarHBondContact O-N 3.14Å; Y324-Q328 PolarHBondContact OH-OE1 2.95Å; E325-Q328 PolarHBondContact O-N 3.21Å; E325-Q328 VanDerWaalsContact O-N 3.15Å; E325-Q328 PolarHBondContact OE2-NE2 3.09Å; L326-Q328 VanDerWaalsContact C-N 3.33Å; Q328-L476 HydrophobicContact CG-CD1 4.27Å; Q328-L476 HydrophobicContact CG-CD2 3.81Å; Q328-L476 HydrophobicContact CG-CG 4.49Å
329N98.4Very high98.5Very high45 Ų4530.3 Ų30.324%0.24115%0.147CC..  trans-118.777.2-174.6-57.6-82.7000111E325 L326 D331 I332 Q333E325-N329 WeakPolarHBondContact O-CB 3.46Å; E325-N329 PolarHBondContact O-N 2.93Å; E325-N329 PolarHBondContact O-ND2 2.89Å; L326-N329 CarbonylContact O-C 3.56Å; L326-N329 PolarHBondContact O-N 3.01Å; N329-D331 VanDerWaalsContact C-N 3.29Å; N329-D331 PolarHBondContact O-N 2.87Å; N329-I332 HydrophobicContact CB-CB 4.09Å; N329-I332 HydrophobicContact CB-CD1 3.8Å; N329-I332 HydrophobicContact CB-CG1 4.07Å; N329-I332 PolarHBondContact O-N 3.32Å; N329-Q333 PolarHBondContact O-N 2.97Å
330Q98.3Very high98.5Very high51 Ų5130.3 Ų30.324%0.23815%0.147CC..Hα-helixtrans-64.2-31.4-174.3-67.6-64.3-57.300113.3L326 A327 Q333 D334 R473 V474L326-Q330 PolarHBondContact O-NE2 3.38Å; A327-Q330 PolarHBondContact O-NE2 2.9Å; Q330-Q333 WeakPolarHBondContact O-CB 3.21Å; Q330-Q333 PolarHBondContact O-N 3.48Å; Q330-D334 WeakPolarHBondContact O-CB 3.49Å; Q330-D334 PolarHBondContact O-N 3.11Å; Q330-R473 VanDerWaalsContact OE1-NH1 3.07Å; Q330-V474 PolarHBondContact NE2-O 2.67Å
331D98.5Very high98.4Very high112 Ų11233.6 Ų33.660%0.59916%0.162SC*.Hα-helixtrans-63.4-42.5174.762.7-55.4000111.8N329 Q333 D334 R335N329-D331 VanDerWaalsContact C-N 3.29Å; N329-D331 PolarHBondContact O-N 2.87Å; D331-Q333 VanDerWaalsContact C-N 3.35Å; D331-D334 PolarHBondContact O-N 3.18Å; D331-R335 WeakPolarHBondContact O-CB 3.23Å; D331-R335 PolarHBondContact O-N 3.27Å
332I98.8Very high98.3Very high13 Ų1336.8 Ų36.87%0.06718%0.182CC..Hα-helixtrans-66.1-41174.5-62.7177.8000110.1L326 N329 R335 L336 Y361 V365 F423 P425L326-I332 HydrophobicContact CD2-CB 4.46Å; L326-I332 HydrophobicContact CD2-CG2 3.81Å; N329-I332 HydrophobicContact CB-CB 4.09Å; N329-I332 HydrophobicContact CB-CD1 3.8Å; N329-I332 HydrophobicContact CB-CG1 4.07Å; N329-I332 PolarHBondContact O-N 3.32Å; I332-R335 PolarHBondContact O-N 3.47Å; I332-L336 VanDerWaalsContact O-CB 3.3Å; I332-L336 WeakPolarHBondContact O-CB 3.46Å; I332-L336 PolarHBondContact O-N 2.59Å; I332-Y361 HydrophobicContact CG2-CE1 4.15Å; I332-V365 HydrophobicContact CG2-CG2 4.11Å; I332-F423 HydrophobicContact CD1-CD1 3.74Å; I332-F423 HydrophobicContact CD1-CE1 4.16Å; I332-F423 HydrophobicContact CG2-CE1 4.22Å; I332-P425 HydrophobicContact CD1-CG 4.2Å; I332-P425 HydrophobicContact CG2-CG 3.91Å
333Q98.8Very high98.2Very high0 Ų037.4 Ų37.40%019%0.185CC..Hα-helixtrans-62.9-43.7176.8-166.3-176.113700112.3L326 N329 Q330 D331 L336 R337 I469 V474L326-Q333 HydrophobicContact CB-CB 4.24Å; L326-Q333 HydrophobicContact CB-CG 4.19Å; L326-Q333 HydrophobicContact CD2-CB 4.2Å; L326-Q333 PolarHBondContact O-NE2 3.03Å; N329-Q333 PolarHBondContact O-N 2.97Å; Q330-Q333 WeakPolarHBondContact O-CB 3.21Å; Q330-Q333 PolarHBondContact O-N 3.48Å; D331-Q333 VanDerWaalsContact C-N 3.35Å; Q333-L336 PolarHBondContact O-N 2.85Å; Q333-R337 WeakPolarHBondContact O-CB 3.22Å; Q333-R337 PolarHBondContact O-N 3.29Å; Q333-I469 HydrophobicContact CG-CD1 4.04Å; Q333-I469 HydrophobicContact CG-CG2 4.48Å; Q333-V474 PolarHBondContact NE2-O 3.23Å
334D98.6Very high97.9Very high51 Ų5138.4 Ų38.427%0.27319%0.19SC..Hα-helixtrans-66.5-42.1179.1-71.2-20.5000111Q330 D331 R337 N338 R473Q330-D334 WeakPolarHBondContact O-CB 3.49Å; Q330-D334 PolarHBondContact O-N 3.11Å; D331-D334 PolarHBondContact O-N 3.18Å; D334-R337 PolarHBondContact O-N 2.89Å; D334-R337 IonicContact OD1-CZ 3.64Å; D334-R337 IonicContact OD1-NH1 2.97Å; D334-R337 PolarHBondContact OD1-NH1 2.98Å; D334-N338 PolarHBondContact O-N 2.99Å; D334-N338 PolarHBondContact O-ND2 3.41Å; D334-N338 PolarHBondContact O-OD1 2.85Å; D334-R473 IonicContact OD1-CZ 3.34Å; D334-R473 IonicContact OD1-NH1 3.76Å; D334-R473 PolarHBondContact OD1-NH1 2.67Å; D334-R473 IonicContact OD1-NH2 3.73Å; D334-R473 PolarHBondContact OD1-NH2 2.9Å; D334-R473 IonicContact OD2-NH1 3.15Å; D334-R473 IonicContact OD2-NH2 3.79Å
335R98.5Very high97.6Very high120 Ų12045.1 Ų45.145%0.45322%0.222SC..Hα-helixtrans-61.9-44.5172.8179.9174.4171.1-161.4-2.8112.4D331 I332 R337 N338 E339 Y361 E426D331-R335 WeakPolarHBondContact O-CB 3.23Å; D331-R335 PolarHBondContact O-N 3.27Å; I332-R335 PolarHBondContact O-N 3.47Å; R335-R337 VanDerWaalsContact C-N 3.33Å; R335-N338 PolarHBondContact O-N 3.46Å; R335-E339 PolarHBondContact O-N 3.43Å; R335-E339 VanDerWaalsContact O-N 3.12Å; R335-Y361 HydrophobicContact CB-CE1 4.04Å; R335-Y361 HydrophobicContact CG-CD1 4.05Å; R335-Y361 HydrophobicContact CG-CE1 3.72Å; R335-Y361 VanDerWaalsContact NH1-CE2 3.29Å; R335-Y361 PolarHBondContact NH1-OH 3.05Å; R335-E426 IonicContact CZ-OE1 3.91Å; R335-E426 IonicContact NH1-OE1 2.69Å; R335-E426 PolarHBondContact NH1-OE1 3.02Å; R335-E426 IonicContact NH2-OE1 2.55Å; R335-E426 PolarHBondContact NH2-OE1 2.98Å
336L98.7Very high97.3Very high0 Ų050.7 Ų50.70%025%0.248CC..Hα-helixtrans-61.6-43.2176.8175.460.8000111.6L326 I332 Q333 N338 E339 I340 Y361 L362 V365 I469L326-L336 HydrophobicContact CD1-CD2 3.76Å; L326-L336 HydrophobicContact CD2-CD2 4.23Å; I332-L336 VanDerWaalsContact O-CB 3.3Å; I332-L336 WeakPolarHBondContact O-CB 3.46Å; I332-L336 PolarHBondContact O-N 2.59Å; Q333-L336 PolarHBondContact O-N 2.85Å; L336-N338 VanDerWaalsContact C-N 3.34Å; L336-N338 PolarHBondContact O-N 2.85Å; L336-E339 PolarHBondContact O-N 3.47Å; L336-I340 HydrophobicContact CD1-CD1 3.91Å; L336-I340 HydrophobicContact CD1-CG1 4.27Å; L336-I340 HydrophobicContact CD2-CD1 4.49Å; L336-I340 HydrophobicContact CG-CD1 3.78Å; L336-I340 WeakPolarHBondContact O-CD1 3.46Å; L336-I340 VanDerWaalsContact O-CG1 3.32Å; L336-I340 WeakPolarHBondContact O-CG1 3.4Å; L336-I340 PolarHBondContact O-N 2.82Å; L336-Y361 HydrophobicContact CB-CD1 4.05Å; L336-Y361 HydrophobicContact CB-CE1 4.26Å; L336-Y361 HydrophobicContact CD1-CD1 4.23Å; L336-L362 VanDerWaalsContact CD1-CA 3.45Å; L336-L362 HydrophobicContact CD1-CB 3.7Å; L336-L362 HydrophobicContact CD1-CD1 3.96Å; L336-L362 HydrophobicContact CD1-CG 4.42Å; L336-L362 HydrophobicContact CD2-CD1 4.23Å; L336-V365 HydrophobicContact CD2-CG1 4.24Å; L336-V365 HydrophobicContact CD2-CG2 4.35Å; L336-I469 HydrophobicContact CD2-CG1 4.32Å; L336-I469 HydrophobicContact CD2-CG2 4.33Å; L336-I469 HydrophobicContact CG-CG2 4.22Å
337R98.4Very high96.8Very high11 Ų1154 Ų544%0.04226%0.264CS..Hα-helixtrans-60.3-44.8176.1-177178.1-58.6101.7-0.6111.9Q333 D334 R335 E339 I340 Q341 I469 F472Q333-R337 WeakPolarHBondContact O-CB 3.22Å; Q333-R337 PolarHBondContact O-N 3.29Å; D334-R337 PolarHBondContact O-N 2.89Å; D334-R337 IonicContact OD1-CZ 3.64Å; D334-R337 IonicContact OD1-NH1 2.97Å; D334-R337 PolarHBondContact OD1-NH1 2.98Å; R335-R337 VanDerWaalsContact C-N 3.33Å; R337-E339 VanDerWaalsContact C-N 3.34Å; R337-E339 PolarHBondContact O-N 3.25Å; R337-I340 PolarHBondContact O-N 2.95Å; R337-Q341 HydrophobicContact CG-CG 4.26Å; R337-Q341 WeakPolarHBondContact O-CB 3.43Å; R337-Q341 WeakPolarHBondContact O-CG 3.14Å; R337-Q341 PolarHBondContact O-N 3.34Å; R337-I469 HydrophobicContact CB-CG2 3.84Å; R337-I469 HydrophobicContact CG-CG2 4.48Å; R337-I469 PolarHBondContact NE-O 3.05Å; R337-F472 PolarHBondContact NH2-O 2.97Å
338N98.3Very high96.3Very high93 Ų9362.1 Ų62.150%0.49730%0.301SS..Hα-helixtrans-59.1-45.8178.1-67.8-15.1000111D334 R335 L336 I340 Q341 T342D334-N338 PolarHBondContact O-N 2.99Å; D334-N338 PolarHBondContact O-ND2 3.41Å; D334-N338 PolarHBondContact O-OD1 2.85Å; R335-N338 PolarHBondContact O-N 3.46Å; L336-N338 VanDerWaalsContact C-N 3.34Å; L336-N338 PolarHBondContact O-N 2.85Å; N338-I340 PolarHBondContact O-N 2.87Å; N338-Q341 PolarHBondContact O-N 2.85Å; N338-T342 PolarHBondContact O-N 2.86Å; N338-T342 PolarHBondContact O-OG1 2.86Å; N338-T342 VanDerWaalsContact O-OG1 3.04Å
339E98.3Very high95.5Very high40 Ų4061.4 Ų61.419%0.18731%0.311CS..Hα-helixtrans-57.3-49.5174.1178.8-175.3-11500111.5R335 L336 R337 Q341 T342 V343 T360 Y361 L362R335-E339 PolarHBondContact O-N 3.43Å; R335-E339 VanDerWaalsContact O-N 3.12Å; L336-E339 PolarHBondContact O-N 3.47Å; R337-E339 VanDerWaalsContact C-N 3.34Å; R337-E339 PolarHBondContact O-N 3.25Å; E339-Q341 VanDerWaalsContact C-N 3.32Å; E339-Q341 PolarHBondContact O-N 3.34Å; E339-T342 PolarHBondContact O-N 3.18Å; E339-V343 HydrophobicContact CG-CG2 4.32Å; E339-V343 WeakPolarHBondContact O-CB 3.36Å; E339-V343 WeakPolarHBondContact O-CG2 3.19Å; E339-V343 PolarHBondContact O-N 2.91Å; E339-T360 PolarHBondContact OE1-N 2.82Å; E339-T360 PolarHBondContact OE2-N 3.5Å; E339-Y361 VanDerWaalsContact CD-CB 3.46Å; E339-Y361 VanDerWaalsContact CD-N 3.27Å; E339-Y361 WeakPolarHBondContact OE1-CB 3.32Å; E339-Y361 PolarHBondContact OE1-N 2.97Å; E339-Y361 WeakPolarHBondContact OE2-CA 3.48Å; E339-Y361 WeakPolarHBondContact OE2-CB 3.41Å; E339-Y361 PolarHBondContact OE2-N 3.39Å; E339-L362 PolarHBondContact OE2-N 3.19Å
340I97.6Very high94.9Very high0 Ų065 Ų650%033%0.326CS..Hα-helixtrans-61.4-43.5-177.7-66.8159.7000110.7L336 R337 N338 L344 M359 A466 I469L336-I340 HydrophobicContact CD1-CD1 3.91Å; L336-I340 HydrophobicContact CD1-CG1 4.27Å; L336-I340 HydrophobicContact CD2-CD1 4.49Å; L336-I340 HydrophobicContact CG-CD1 3.78Å; L336-I340 WeakPolarHBondContact O-CD1 3.46Å; L336-I340 VanDerWaalsContact O-CG1 3.32Å; L336-I340 WeakPolarHBondContact O-CG1 3.4Å; L336-I340 PolarHBondContact O-N 2.82Å; R337-I340 PolarHBondContact O-N 2.95Å; N338-I340 PolarHBondContact O-N 2.87Å; I340-L344 HydrophobicContact CG2-CD1 3.8Å; I340-L344 HydrophobicContact CG2-CG 4.31Å; I340-L344 WeakPolarHBondContact O-CB 3.48Å; I340-L344 WeakPolarHBondContact O-CG 3.34Å; I340-L344 PolarHBondContact O-N 2.87Å; I340-M359 HydrophobicContact CG1-SD 4.14Å; I340-M359 HydrophobicContact CG2-CE 4.06Å; I340-A466 HydrophobicContact CD1-CB 4.45Å; I340-A466 HydrophobicContact CG2-CB 4.37Å; I340-I469 HydrophobicContact CD1-CB 3.96Å; I340-I469 HydrophobicContact CD1-CG2 3.91Å
341Q95.9Very high94.5Very high70 Ų7063.5 Ų63.533%0.32732%0.32SS..Hα-helixtrans-63.9-47.9178.9-74.7178.5-16.800111.5R337 N338 E339 V343 L344 E345R337-Q341 HydrophobicContact CG-CG 4.26Å; R337-Q341 WeakPolarHBondContact O-CB 3.43Å; R337-Q341 WeakPolarHBondContact O-CG 3.14Å; R337-Q341 PolarHBondContact O-N 3.34Å; N338-Q341 PolarHBondContact O-N 2.85Å; E339-Q341 VanDerWaalsContact C-N 3.32Å; E339-Q341 PolarHBondContact O-N 3.34Å; Q341-V343 PolarHBondContact O-N 3.47Å; Q341-L344 PolarHBondContact O-N 2.95Å; Q341-E345 WeakPolarHBondContact O-CG 3.34Å; Q341-E345 PolarHBondContact O-N 2.87Å
342T96.6Very high94.1Very high70 Ų7060 Ų6043%0.42930%0.303SS..Hα-helixtrans-57.8-48176.7-59.70000111.8N338 E339 L344 E345 E346N338-T342 PolarHBondContact O-N 2.86Å; N338-T342 PolarHBondContact O-OG1 2.86Å; N338-T342 VanDerWaalsContact O-OG1 3.04Å; E339-T342 PolarHBondContact O-N 3.18Å; T342-L344 VanDerWaalsContact C-N 3.3Å; T342-L344 PolarHBondContact O-N 2.81Å; T342-E345 PolarHBondContact O-N 3.47Å; T342-E346 WeakPolarHBondContact O-CG 3.31Å; T342-E346 PolarHBondContact O-N 3.02Å; T342-E346 VanDerWaalsContact O-N 3.08Å
343V96.1Very high93.6Very high13 Ų1362.3 Ų62.38%0.07931%0.311CS..Hα-helixtrans-64.5-35.8179.3171.70000111.8E339 Q341 Q347 S355 A358 M359E339-V343 HydrophobicContact CG-CG2 4.32Å; E339-V343 WeakPolarHBondContact O-CB 3.36Å; E339-V343 WeakPolarHBondContact O-CG2 3.19Å; E339-V343 PolarHBondContact O-N 2.91Å; Q341-V343 PolarHBondContact O-N 3.47Å; V343-Q347 WeakPolarHBondContact O-CB 3.44Å; V343-Q347 WeakPolarHBondContact O-CG 2.94Å; V343-Q347 PolarHBondContact O-N 2.76Å; V343-S355 WeakPolarHBondContact CG1-O 3.48Å; V343-A358 HydrophobicContact CG1-CB 4.07Å; V343-A358 HydrophobicContact CG2-CB 4.41Å; V343-M359 HydrophobicContact CB-CE 4.33Å; V343-M359 HydrophobicContact CB-CG 4.29Å; V343-M359 HydrophobicContact CG1-CE 3.97Å; V343-M359 HydrophobicContact CG1-CG 4.08Å; V343-M359 HydrophobicContact CG2-CG 4.3Å
344L93.4Very high93.1Very high21 Ų2166.1 Ų66.111%0.1133%0.329CS..Hα-helixtrans-69-41.8176-74.9174.4000111.9I340 Q341 T342 E346 Q347 E348 G349 L351I340-L344 HydrophobicContact CG2-CD1 3.8Å; I340-L344 HydrophobicContact CG2-CG 4.31Å; I340-L344 WeakPolarHBondContact O-CB 3.48Å; I340-L344 WeakPolarHBondContact O-CG 3.34Å; I340-L344 PolarHBondContact O-N 2.87Å; Q341-L344 PolarHBondContact O-N 2.95Å; T342-L344 VanDerWaalsContact C-N 3.3Å; T342-L344 PolarHBondContact O-N 2.81Å; L344-E346 VanDerWaalsContact C-N 3.32Å; L344-E346 PolarHBondContact O-N 2.84Å; L344-Q347 CarbonylContact O-C 3.54Å; L344-Q347 VanDerWaalsContact O-C 3.3Å; L344-Q347 WeakPolarHBondContact O-CA 3.28Å; L344-Q347 PolarHBondContact O-N 3.35Å; L344-E348 PolarHBondContact O-N 3.47Å; L344-G349 WeakPolarHBondContact O-CA 3.33Å; L344-G349 PolarHBondContact O-N 3.4Å; L344-L351 HydrophobicContact CD2-CD2 3.63Å; L344-L351 HydrophobicContact CD2-CG 3.85Å
345E92.6Very high92.7Very high148 Ų14863.7 Ų63.769%0.69232%0.316SS*.Hα-helixtrans-59.2-43.2176.1-73.8170.8-176.300111.6Q341 T342 Q347 E348Q341-E345 WeakPolarHBondContact O-CG 3.34Å; Q341-E345 PolarHBondContact O-N 2.87Å; T342-E345 PolarHBondContact O-N 3.47Å; E345-Q347 PolarHBondContact O-N 3.39Å; E345-E348 PolarHBondContact O-N 2.85Å
346E91Very high92.4Very high136 Ų13658.3 Ų58.364%0.63630%0.296SS*.THydrogen-bonded Turntrans-64.4-17.9174.4-69.8176.617600113.8T342 L344T342-E346 WeakPolarHBondContact O-CG 3.31Å; T342-E346 PolarHBondContact O-N 3.02Å; T342-E346 VanDerWaalsContact O-N 3.08Å; L344-E346 VanDerWaalsContact C-N 3.32Å; L344-E346 PolarHBondContact O-N 2.84Å
347Q88.7Confident92Very high69 Ų6965 Ų6532%0.32233%0.325SS..THydrogen-bonded Turntrans-115.828.8-176.2-61.8-71.7-5000111.9V343 L344 E345 G349 Q350 T352V343-Q347 WeakPolarHBondContact O-CB 3.44Å; V343-Q347 WeakPolarHBondContact O-CG 2.94Å; V343-Q347 PolarHBondContact O-N 2.76Å; L344-Q347 CarbonylContact O-C 3.54Å; L344-Q347 VanDerWaalsContact O-C 3.3Å; L344-Q347 WeakPolarHBondContact O-CA 3.28Å; L344-Q347 PolarHBondContact O-N 3.35Å; E345-Q347 PolarHBondContact O-N 3.39Å; Q347-G349 PolarHBondContact O-N 2.63Å; Q347-Q350 PolarHBondContact O-N 3.37Å; Q347-T352 PolarHBondContact OE1-OG1 3.4Å
348E88.2Confident91.7Very high175 Ų17566.9 Ų66.982%0.81834%0.343SS*.THydrogen-bonded Turntrans57.132177-56.4178.2-169.200113.6L344 E345 Q350L344-E348 PolarHBondContact O-N 3.47Å; E345-E348 PolarHBondContact O-N 2.85Å; E348-Q350 VanDerWaalsContact C-N 3.26Å; E348-Q350 PolarHBondContact O-N 2.72Å
349G82.7Confident91.6Very high51 Ų5162.4 Ų62.453%0.52632%0.319SS..THydrogen-bonded Turntrans75.57.6-179.400000114.7L344 Q347L344-G349 WeakPolarHBondContact O-CA 3.33Å; L344-G349 PolarHBondContact O-N 3.4Å; Q347-G349 PolarHBondContact O-N 2.63Å
350Q84.8Confident91.5Very high120 Ų12063.6 Ų63.656%0.56133%0.329SS*.  trans-102.5135.8-175.3-60.8-1719.800112.8Q347 E348 T352Q347-Q350 PolarHBondContact O-N 3.37Å; E348-Q350 VanDerWaalsContact C-N 3.26Å; E348-Q350 PolarHBondContact O-N 2.72Å; Q350-T352 HydrophobicContact CB-CG2 4.1Å; Q350-T352 PolarHBondContact O-N 2.61Å
351L89.4Confident91.6Very high21 Ų2164.2 Ų64.211%0.1133%0.331CS..  trans-77.387.6167.6-75.1171000109.8F146 I150 L344 S355 I356 M359 A466 Q467F146-L351 WeakPolarHBondContact CE1-O 3.48Å; F146-L351 WeakPolarHBondContact CZ-O 3.24Å; I150-L351 HydrophobicContact CD1-CB 3.8Å; I150-L351 WeakPolarHBondContact CD1-O 3.45Å; L344-L351 HydrophobicContact CD2-CD2 3.63Å; L344-L351 HydrophobicContact CD2-CG 3.85Å; L351-S355 WeakPolarHBondContact CA-OG 3.39Å; L351-I356 HydrophobicContact CD2-CD1 3.82Å; L351-M359 HydrophobicContact CD2-CE 3.85Å; L351-A466 HydrophobicContact CD2-CB 4.24Å; L351-Q467 HydrophobicContact CD1-CG 3.68Å
352T90.5Very high91.7Very high38 Ų3860.9 Ų60.923%0.23332%0.316CS..  trans-88.4164.9172.572.70000111.7F146 Q347 Q350 E354 S355 I356F146-T352 VanDerWaalsContact CE1-C 3.43Å; F146-T352 WeakPolarHBondContact CZ-O 3.48Å; Q347-T352 PolarHBondContact OE1-OG1 3.4Å; Q350-T352 HydrophobicContact CB-CG2 4.1Å; Q350-T352 PolarHBondContact O-N 2.61Å; T352-E354 PolarHBondContact O-N 3.19Å; T352-S355 PolarHBondContact N-OG 2.71Å; T352-S355 PolarHBondContact O-N 3.39Å; T352-S355 PolarHBondContact O-OG 2.88Å; T352-S355 PolarHBondContact OG1-N 3.43Å; T352-I356 PolarHBondContact O-N 3.43Å
353Y87.9Confident91.8Very high61 Ų6159.2 Ų59.224%0.23930%0.304CS..Hα-helixtrans-59.4-34.4176-173-91.4000112M142 K143 F146 K357 M459M142-Y353 HydrophobicContact CB-CE2 4.12Å; K143-Y353 HydrophobicContact CB-CD2 4.24Å; K143-Y353 HydrophobicContact CB-CE2 4.28Å; K143-Y353 HydrophobicContact CB-CG 4.44Å; K143-Y353 HydrophobicContact CD-CD1 4.38Å; K143-Y353 HydrophobicContact CG-CD2 4.45Å; K143-Y353 HydrophobicContact CG-CG 4.23Å; F146-Y353 HydrophobicContact CB-CD2 4.27Å; F146-Y353 AromaticContact CD2-CD2 3.61Å; F146-Y353 HydrophobicContact CD2-CD2 3.61Å; F146-Y353 HydrophobicContact CD2-CG 4.37Å; F146-Y353 VanDerWaalsContact CE1-N 3.28Å; F146-Y353 HydrophobicContact CE2-CD2 4.14Å; F146-Y353 HydrophobicContact CG-CD2 4.05Å; F146-Y353 VanDerWaalsContact CZ-N 3.26Å; Y353-K357 PolarHBondContact O-N 2.85Å; Y353-M459 HydrophobicContact CE2-SD 4.46Å
354E88.6Confident91.9Very high80 Ų8059.2 Ų59.237%0.37430%0.304SS..Hα-helixtrans-75.8-36.2178.3-53-52.8148.900111.5K143 T352 I356 K357 A358K143-E354 IonicContact NZ-OE1 2.83Å; K143-E354 PolarHBondContact NZ-OE1 2.76Å; T352-E354 PolarHBondContact O-N 3.19Å; E354-I356 PolarHBondContact O-N 3.41Å; E354-K357 WeakPolarHBondContact O-CB 3.44Å; E354-K357 PolarHBondContact O-N 3.33Å; E354-K357 VanDerWaalsContact O-N 3.08Å; E354-A358 PolarHBondContact O-N 2.92Å
355S91.3Very high92.1Very high0 Ų058.2 Ų58.20%030%0.298CS..Hα-helixtrans-56.3-48.1174.575.60000111.8V343 L351 T352 K357 A358 M359V343-S355 WeakPolarHBondContact CG1-O 3.48Å; L351-S355 WeakPolarHBondContact CA-OG 3.39Å; T352-S355 PolarHBondContact N-OG 2.71Å; T352-S355 PolarHBondContact O-N 3.39Å; T352-S355 PolarHBondContact O-OG 2.88Å; T352-S355 PolarHBondContact OG1-N 3.43Å; S355-K357 PolarHBondContact O-N 3.22Å; S355-A358 WeakPolarHBondContact O-CB 3.11Å; S355-A358 PolarHBondContact O-N 3.44Å; S355-M359 WeakPolarHBondContact O-CG 3.11Å; S355-M359 PolarHBondContact O-N 3.49Å
356I91.7Very high92.4Very high7 Ų751.5 Ų51.54%0.03627%0.267CS..Hα-helixtrans-63.1-31.6178.9-68.3-63.4000111.9F146 L351 T352 E354 M359 R462 I463 A466F146-I356 HydrophobicContact CE2-CG1 4.15Å; F146-I356 HydrophobicContact CZ-CG1 4.22Å; L351-I356 HydrophobicContact CD2-CD1 3.82Å; T352-I356 PolarHBondContact O-N 3.43Å; E354-I356 PolarHBondContact O-N 3.41Å; I356-M359 HydrophobicContact CD1-CE 4.43Å; I356-M359 HydrophobicContact CD1-SD 4.09Å; I356-R462 HydrophobicContact CD1-CB 4.4Å; I356-R462 HydrophobicContact CG2-CB 3.69Å; I356-R462 VanDerWaalsContact CG2-CD 3.49Å; I356-R462 HydrophobicContact CG2-CG 4.2Å; I356-I463 HydrophobicContact CD1-CG1 3.71Å; I356-I463 HydrophobicContact CG1-CG1 3.87Å; I356-A466 HydrophobicContact CD1-CB 4.38Å
357K89.4Confident92.8Very high142 Ų14245.9 Ų45.962%0.61724%0.243SC*.Hα-helixtrans-74.9-30.9177.2-173.2-176.3170.2-163.20111.8Y353 E354 S355Y353-K357 PolarHBondContact O-N 2.85Å; E354-K357 WeakPolarHBondContact O-CB 3.44Å; E354-K357 PolarHBondContact O-N 3.33Å; E354-K357 VanDerWaalsContact O-N 3.08Å; S355-K357 PolarHBondContact O-N 3.22Å
358A92.6Very high93.3Very high49 Ų4942.6 Ų42.641%0.40523%0.228SC..Hα-helixtrans-74.4-24.8179.300000113.6V343 E354 S355 T360V343-A358 HydrophobicContact CG1-CB 4.07Å; V343-A358 HydrophobicContact CG2-CB 4.41Å; E354-A358 PolarHBondContact O-N 2.92Å; S355-A358 WeakPolarHBondContact O-CB 3.11Å; S355-A358 PolarHBondContact O-N 3.44Å; A358-T360 PolarHBondContact O-N 3.17Å; A358-T360 PolarHBondContact O-OG1 2.73Å
359M95.8Very high93.8Very high0 Ų034.3 Ų34.30%019%0.189CC..  trans-69.987178.8-62.5170.6-174.600111.8I340 V343 L351 S355 I356 L362 N363 A466I340-M359 HydrophobicContact CG1-SD 4.14Å; I340-M359 HydrophobicContact CG2-CE 4.06Å; V343-M359 HydrophobicContact CB-CE 4.33Å; V343-M359 HydrophobicContact CB-CG 4.29Å; V343-M359 HydrophobicContact CG1-CE 3.97Å; V343-M359 HydrophobicContact CG1-CG 4.08Å; V343-M359 HydrophobicContact CG2-CG 4.3Å; L351-M359 HydrophobicContact CD2-CE 3.85Å; S355-M359 WeakPolarHBondContact O-CG 3.11Å; S355-M359 PolarHBondContact O-N 3.49Å; I356-M359 HydrophobicContact CD1-CE 4.43Å; I356-M359 HydrophobicContact CD1-SD 4.09Å; M359-L362 HydrophobicContact CB-CB 3.74Å; M359-L362 HydrophobicContact CB-CD2 4.03Å; M359-L362 HydrophobicContact CG-CD2 4.48Å; M359-L362 HydrophobicContact SD-CD2 3.65Å; M359-N363 PolarHBondContact O-N 3.39Å; M359-N363 PolarHBondContact O-ND2 2.84Å; M359-A466 HydrophobicContact CE-CB 4.43Å; M359-A466 HydrophobicContact SD-CB 4.08Å
360T97.1Very high94.5Very high64 Ų6432.3 Ų32.339%0.39317%0.166SC..Hα-helixtrans-76.9-45-173.2-62.80000111.3E339 A358 N363 Q364 P430E339-T360 PolarHBondContact OE1-N 2.82Å; E339-T360 PolarHBondContact OE2-N 3.5Å; A358-T360 PolarHBondContact O-N 3.17Å; A358-T360 PolarHBondContact O-OG1 2.73Å; T360-N363 VanDerWaalsContact O-CB 3.3Å; T360-N363 WeakPolarHBondContact O-CB 3.35Å; T360-N363 PolarHBondContact O-N 3.03Å; T360-N363 VanDerWaalsContact O-N 3.12Å; T360-Q364 WeakPolarHBondContact O-CG 3.47Å; T360-Q364 PolarHBondContact O-N 3.09Å; T360-Q364 VanDerWaalsContact O-N 3.1Å; T360-P430 HydrophobicContact CG2-CG 4.44Å
361Y98.6Very high95.2Very high13 Ų1326.6 Ų26.65%0.05114%0.139CC..Hα-helixtrans-67.7-36.2178.3-162.5-113000111.6I332 R335 L336 E339 N363 Q364 V365 P425I332-Y361 HydrophobicContact CG2-CE1 4.15Å; R335-Y361 HydrophobicContact CB-CE1 4.04Å; R335-Y361 HydrophobicContact CG-CD1 4.05Å; R335-Y361 HydrophobicContact CG-CE1 3.72Å; R335-Y361 VanDerWaalsContact NH1-CE2 3.29Å; R335-Y361 PolarHBondContact NH1-OH 3.05Å; L336-Y361 HydrophobicContact CB-CD1 4.05Å; L336-Y361 HydrophobicContact CB-CE1 4.26Å; L336-Y361 HydrophobicContact CD1-CD1 4.23Å; E339-Y361 VanDerWaalsContact CD-CB 3.46Å; E339-Y361 VanDerWaalsContact CD-N 3.27Å; E339-Y361 WeakPolarHBondContact OE1-CB 3.32Å; E339-Y361 PolarHBondContact OE1-N 2.97Å; E339-Y361 WeakPolarHBondContact OE2-CA 3.48Å; E339-Y361 WeakPolarHBondContact OE2-CB 3.41Å; E339-Y361 PolarHBondContact OE2-N 3.39Å; Y361-N363 PolarHBondContact O-N 2.94Å; Y361-Q364 HydrophobicContact CD2-CB 4.44Å; Y361-Q364 VanDerWaalsContact CD2-OE1 3.27Å; Y361-Q364 WeakPolarHBondContact O-CA 3.32Å; Y361-Q364 WeakPolarHBondContact O-CB 3.09Å; Y361-Q364 PolarHBondContact O-N 3.48Å; Y361-V365 HydrophobicContact CD1-CG2 4.06Å; Y361-V365 HydrophobicContact CE1-CG2 3.93Å; Y361-V365 WeakPolarHBondContact O-CG2 3.25Å; Y361-V365 PolarHBondContact O-N 2.91Å; Y361-P425 HydrophobicContact CE2-CB 3.85Å
362L98.6Very high95.6Very high0 Ų025.8 Ų25.80%014%0.135CC..Hα-helixtrans-54.8-41.9168.9179.959.6000112.1L336 E339 M359 Q364 V365 I366 R462 L465 A466L336-L362 VanDerWaalsContact CD1-CA 3.45Å; L336-L362 HydrophobicContact CD1-CB 3.7Å; L336-L362 HydrophobicContact CD1-CD1 3.96Å; L336-L362 HydrophobicContact CD1-CG 4.42Å; L336-L362 HydrophobicContact CD2-CD1 4.23Å; E339-L362 PolarHBondContact OE2-N 3.19Å; M359-L362 HydrophobicContact CB-CB 3.74Å; M359-L362 HydrophobicContact CB-CD2 4.03Å; M359-L362 HydrophobicContact CG-CD2 4.48Å; M359-L362 HydrophobicContact SD-CD2 3.65Å; L362-Q364 VanDerWaalsContact C-N 3.34Å; L362-V365 PolarHBondContact O-N 3.47Å; L362-I366 HydrophobicContact CD1-CD1 4.01Å; L362-I366 HydrophobicContact CD1-CG1 4.35Å; L362-I366 HydrophobicContact CG-CD1 4.01Å; L362-I366 VanDerWaalsContact O-CG1 3.29Å; L362-I366 WeakPolarHBondContact O-CG1 3.36Å; L362-I366 PolarHBondContact O-N 3.37Å; L362-R462 HydrophobicContact CD2-CB 3.93Å; L362-R462 HydrophobicContact CD2-CG 4.17Å; L362-R462 HydrophobicContact CG-CG 4.46Å; L362-L465 HydrophobicContact CD1-CB 4Å; L362-L465 HydrophobicContact CD1-CD1 4.38Å; L362-A466 HydrophobicContact CD2-CB 4.21Å
363N98Very high95.9Very high35 Ų3524.5 Ų24.519%0.18713%0.126CC..Hα-helixtrans-65.3-38.1175.8-73.5-49.3000112.7M359 T360 Y361 S367 R462M359-N363 PolarHBondContact O-N 3.39Å; M359-N363 PolarHBondContact O-ND2 2.84Å; T360-N363 VanDerWaalsContact O-CB 3.3Å; T360-N363 WeakPolarHBondContact O-CB 3.35Å; T360-N363 PolarHBondContact O-N 3.03Å; T360-N363 VanDerWaalsContact O-N 3.12Å; Y361-N363 PolarHBondContact O-N 2.94Å; N363-S367 VanDerWaalsContact O-CB 3.29Å; N363-S367 WeakPolarHBondContact O-CB 3.21Å; N363-S367 PolarHBondContact O-N 2.88Å; N363-S367 PolarHBondContact O-OG 3.29Å; N363-R462 PolarHBondContact OD1-NE 2.98Å; N363-R462 PolarHBondContact OD1-NH2 3.01Å
364Q98.8Very high96.4Very high14 Ų1421.7 Ų21.77%0.06512%0.115CC..Hα-helixtrans-63.7-48.4176.4-67.417912.400111.3T360 Y361 L362 I366 S367 E368 P425 F428T360-Q364 WeakPolarHBondContact O-CG 3.47Å; T360-Q364 PolarHBondContact O-N 3.09Å; T360-Q364 VanDerWaalsContact O-N 3.1Å; Y361-Q364 HydrophobicContact CD2-CB 4.44Å; Y361-Q364 VanDerWaalsContact CD2-OE1 3.27Å; Y361-Q364 WeakPolarHBondContact O-CA 3.32Å; Y361-Q364 WeakPolarHBondContact O-CB 3.09Å; Y361-Q364 PolarHBondContact O-N 3.48Å; L362-Q364 VanDerWaalsContact C-N 3.34Å; Q364-I366 PolarHBondContact O-N 3.26Å; Q364-S367 PolarHBondContact O-N 3.44Å; Q364-S367 VanDerWaalsContact O-N 3.13Å; Q364-E368 WeakPolarHBondContact O-CB 3.24Å; Q364-E368 PolarHBondContact O-N 3.46Å; Q364-P425 HydrophobicContact CB-CB 3.99Å; Q364-P425 WeakPolarHBondContact CB-O 3.46Å; Q364-F428 HydrophobicContact CB-CB 4.15Å; Q364-F428 HydrophobicContact CG-CB 4.09Å; Q364-F428 WeakPolarHBondContact CG-O 3.35Å
365V98.9Very high96.7Very high0 Ų018.5 Ų18.50%010%0.101CC..Hα-helixtrans-59.6-45.4177.8173.80000111.2L326 I332 L336 Y361 L362 S367 T369 F423 P425L326-V365 HydrophobicContact CD1-CG1 4.46Å; L326-V365 HydrophobicContact CD2-CG1 4Å; L326-V365 HydrophobicContact CG-CG1 4.37Å; I332-V365 HydrophobicContact CG2-CG2 4.11Å; L336-V365 HydrophobicContact CD2-CG1 4.24Å; L336-V365 HydrophobicContact CD2-CG2 4.35Å; Y361-V365 HydrophobicContact CD1-CG2 4.06Å; Y361-V365 HydrophobicContact CE1-CG2 3.93Å; Y361-V365 WeakPolarHBondContact O-CG2 3.25Å; Y361-V365 PolarHBondContact O-N 2.91Å; L362-V365 PolarHBondContact O-N 3.47Å; V365-S367 VanDerWaalsContact C-N 3.33Å; V365-S367 PolarHBondContact O-N 2.94Å; V365-T369 WeakPolarHBondContact O-CB 3.37Å; V365-T369 PolarHBondContact O-N 3.24Å; V365-T369 PolarHBondContact O-OG1 3.18Å; V365-F423 HydrophobicContact CG1-CE1 4.37Å; V365-F423 HydrophobicContact CG1-CZ 3.93Å; V365-P425 HydrophobicContact CG2-CB 4.06Å; V365-P425 HydrophobicContact CG2-CG 3.84Å
366I98.7Very high96.9Very high6 Ų621.3 Ų21.33%0.03112%0.118CC..Hα-helixtrans-63.7-40.9176-68.5167.9000110.9L362 Q364 T369 L370 A461 R462 L465L362-I366 HydrophobicContact CD1-CD1 4.01Å; L362-I366 HydrophobicContact CD1-CG1 4.35Å; L362-I366 HydrophobicContact CG-CD1 4.01Å; L362-I366 VanDerWaalsContact O-CG1 3.29Å; L362-I366 WeakPolarHBondContact O-CG1 3.36Å; L362-I366 PolarHBondContact O-N 3.37Å; Q364-I366 PolarHBondContact O-N 3.26Å; I366-T369 WeakPolarHBondContact O-CB 3.16Å; I366-T369 PolarHBondContact O-N 2.85Å; I366-L370 HydrophobicContact CG2-CD1 4.09Å; I366-L370 WeakPolarHBondContact O-CG 3.48Å; I366-L370 PolarHBondContact O-N 2.94Å; I366-A461 HydrophobicContact CD1-CB 4.36Å; I366-R462 HydrophobicContact CD1-CB 4.36Å; I366-R462 HydrophobicContact CD1-CG 3.61Å; I366-L465 HydrophobicContact CD1-CD1 3.85Å; I366-L465 HydrophobicContact CG1-CD1 3.57Å
367S98.7Very high97.1Very high19 Ų1921.2 Ų21.213%0.13312%0.117CC..Hα-helixtrans-69.6-38-177.4-57.70000112.3N363 Q364 V365 L370 R371 F428 W441N363-S367 VanDerWaalsContact O-CB 3.29Å; N363-S367 WeakPolarHBondContact O-CB 3.21Å; N363-S367 PolarHBondContact O-N 2.88Å; N363-S367 PolarHBondContact O-OG 3.29Å; Q364-S367 PolarHBondContact O-N 3.44Å; Q364-S367 VanDerWaalsContact O-N 3.13Å; V365-S367 VanDerWaalsContact C-N 3.33Å; V365-S367 PolarHBondContact O-N 2.94Å; S367-L370 PolarHBondContact O-N 3.5Å; S367-R371 PolarHBondContact O-N 3.03Å; S367-F428 VanDerWaalsContact CB-CG 3.45Å; S367-W441 PolarHBondContact O-NE1 3.41Å
368E98.8Very high97.4Very high0 Ų015.2 Ų15.20%09%0.092CC..Hα-helixtrans-67.5-38.9173-179.863.217700111.7Q364 L370 R371 L372 F423 D424 R427 F428Q364-E368 WeakPolarHBondContact O-CB 3.24Å; Q364-E368 PolarHBondContact O-N 3.46Å; E368-L370 VanDerWaalsContact C-N 3.32Å; E368-L370 PolarHBondContact O-N 2.94Å; E368-R371 WeakPolarHBondContact O-CB 3.23Å; E368-R371 PolarHBondContact O-N 2.9Å; E368-R371 IonicContact OE1-CZ 2.71Å; E368-R371 IonicContact OE1-NE 2.81Å; E368-R371 PolarHBondContact OE1-NE 2.95Å; E368-R371 IonicContact OE1-NH2 3.67Å; E368-R371 PolarHBondContact OE1-NH2 2.94Å; E368-R371 WeakPolarHBondContact OE2-CD 3.41Å; E368-R371 IonicContact OE2-CZ 3.2Å; E368-R371 IonicContact OE2-NE 3.51Å; E368-R371 PolarHBondContact OE2-NE 3.12Å; E368-R371 IonicContact OE2-NH2 3.61Å; E368-L372 HydrophobicContact CG-CD1 4.44Å; E368-L372 PolarHBondContact O-N 2.9Å; E368-F423 HydrophobicContact CB-CE2 4.17Å; E368-F423 HydrophobicContact CB-CZ 4.36Å; E368-F423 HydrophobicContact CG-CD2 3.76Å; E368-F423 HydrophobicContact CG-CE2 3.79Å; E368-F423 HydrophobicContact CG-CG 4.11Å; E368-F423 HydrophobicContact CG-CZ 4.22Å; E368-D424 VanDerWaalsContact CD-O 3.31Å; E368-D424 PolarHBondContact OE1-N 2.87Å; E368-R427 IonicContact OE1-NE 3.38Å; E368-F428 HydrophobicContact CB-CD2 4Å; E368-F428 HydrophobicContact CB-CE2 4.14Å; E368-F428 VanDerWaalsContact OE2-CE2 3.26Å; E368-F428 WeakPolarHBondContact OE2-CE2 3.25Å
369T98.8Very high97.6Very high1 Ų113.9 Ų13.91%0.0068%0.077CC..Hα-helixtrans-57.1-47.4171-56.50000110.9C322 V365 I366 R371 L372 Y373C322-T369 HydrophobicContact CB-CG2 3.9Å; V365-T369 WeakPolarHBondContact O-CB 3.37Å; V365-T369 PolarHBondContact O-N 3.24Å; V365-T369 PolarHBondContact O-OG1 3.18Å; I366-T369 WeakPolarHBondContact O-CB 3.16Å; I366-T369 PolarHBondContact O-N 2.85Å; T369-R371 VanDerWaalsContact C-N 3.28Å; T369-R371 PolarHBondContact O-N 3.41Å; T369-L372 PolarHBondContact O-N 3.38Å; T369-Y373 HydrophobicContact CG2-CD2 4.06Å; T369-Y373 WeakPolarHBondContact O-CB 3.49Å; T369-Y373 WeakPolarHBondContact O-CD2 3.49Å; T369-Y373 PolarHBondContact O-N 3.25Å
370L98.5Very high97.7Very high9 Ų915.2 Ų15.25%0.0478%0.083CC..Hα-helixtrans-68.8-25.2179.9-74.4171.1000113.5T318 I366 S367 E368 T374 W441 P443 F444T318-L370 HydrophobicContact CG2-CD2 3.71Å; T318-L370 HydrophobicContact CG2-CG 3.98Å; I366-L370 HydrophobicContact CG2-CD1 4.09Å; I366-L370 WeakPolarHBondContact O-CG 3.48Å; I366-L370 PolarHBondContact O-N 2.94Å; S367-L370 PolarHBondContact O-N 3.5Å; E368-L370 VanDerWaalsContact C-N 3.32Å; E368-L370 PolarHBondContact O-N 2.94Å; L370-T374 PolarHBondContact O-OG1 3.38Å; L370-W441 HydrophobicContact CB-CZ2 4.24Å; L370-W441 HydrophobicContact CD1-CZ2 4.3Å; L370-P443 HydrophobicContact CB-CB 3.77Å; L370-P443 HydrophobicContact CB-CG 4.03Å; L370-P443 HydrophobicContact CD1-CB 4.38Å; L370-P443 HydrophobicContact CD1-CG 4.4Å; L370-P443 HydrophobicContact CD2-CB 4.31Å; L370-P443 HydrophobicContact CG-CB 4.39Å; L370-F444 HydrophobicContact CD1-CE2 3.56Å; L370-F444 HydrophobicContact CD1-CZ 3.7Å
371R98.6Very high97.7Very high0 Ų012.3 Ų12.30%07%0.065CC..Hα-helixtrans-67.6-56.9170.4-173.4-165.466.979.4-5109.9S367 E368 T369 T374 H411 Y417 P420 T422 F428S367-R371 PolarHBondContact O-N 3.03Å; E368-R371 WeakPolarHBondContact O-CB 3.23Å; E368-R371 PolarHBondContact O-N 2.9Å; E368-R371 IonicContact OE1-CZ 2.71Å; E368-R371 IonicContact OE1-NE 2.81Å; E368-R371 PolarHBondContact OE1-NE 2.95Å; E368-R371 IonicContact OE1-NH2 3.67Å; E368-R371 PolarHBondContact OE1-NH2 2.94Å; E368-R371 WeakPolarHBondContact OE2-CD 3.41Å; E368-R371 IonicContact OE2-CZ 3.2Å; E368-R371 IonicContact OE2-NE 3.51Å; E368-R371 PolarHBondContact OE2-NE 3.12Å; E368-R371 IonicContact OE2-NH2 3.61Å; T369-R371 VanDerWaalsContact C-N 3.28Å; T369-R371 PolarHBondContact O-N 3.41Å; R371-T374 PolarHBondContact O-OG1 2.9Å; R371-H411 HydrophobicContact CG-CB 3.75Å; R371-H411 WeakPolarHBondContact CG-O 3.39Å; R371-H411 PolarHBondContact NH1-O 3.37Å; R371-H411 WeakPolarHBondContact O-CB 3.28Å; R371-H411 PolarHBondContact O-ND1 3.05Å; R371-Y417 VanDerWaalsContact CD-CD1 3.43Å; R371-Y417 VanDerWaalsContact CD-CE1 3.49Å; R371-Y417 HydrophobicContact CG-CE1 4.34Å; R371-P420 VanDerWaalsContact CZ-O 3.27Å; R371-P420 PolarHBondContact NH1-O 2.76Å; R371-P420 PolarHBondContact NH2-O 2.77Å; R371-T422 PolarHBondContact NH2-O 3.08Å; R371-T422 VanDerWaalsContact NH2-O 3.17Å; R371-F428 HydrophobicContact CB-CE2 4.17Å; R371-F428 HydrophobicContact CB-CZ 4.08Å
372L97.9Very high97.6Very high3 Ų314.1 Ų14.12%0.0167%0.073CC..Hα-helixtrans-65.8-41.6-177-81167.9000112.7E368 T369 R412 P420 F423E368-L372 HydrophobicContact CG-CD1 4.44Å; E368-L372 PolarHBondContact O-N 2.9Å; T369-L372 PolarHBondContact O-N 3.38Å; L372-R412 PolarHBondContact O-NE 3.16Å; L372-R412 PolarHBondContact O-NH2 2.85Å; L372-P420 VanDerWaalsContact CD2-O 3.26Å; L372-P420 WeakPolarHBondContact CD2-O 3.31Å; L372-F423 HydrophobicContact CD1-CB 3.81Å; L372-F423 HydrophobicContact CD1-CD2 3.54Å; L372-F423 HydrophobicContact CD1-CG 4.14Å
373Y97.4Very high97.6Very high12 Ų1214.1 Ų14.15%0.0477%0.074CC..SBendtrans-110.469.4-176.5-58.6-87.1000110.9Y321 Y324 E325 T369 L375 L484 Y486 L493Y321-Y373 AromaticContact CD1-CD1 3.52Å; Y321-Y373 HydrophobicContact CD1-CD1 3.52Å; Y321-Y373 AromaticContact CD1-CE1 3.63Å; Y321-Y373 HydrophobicContact CD1-CE1 3.63Å; Y321-Y373 HydrophobicContact CD1-CG 4.07Å; Y321-Y373 AromaticContact CD2-CD1 3.88Å; Y321-Y373 HydrophobicContact CD2-CD1 3.88Å; Y321-Y373 AromaticContact CD2-CG 3.79Å; Y321-Y373 HydrophobicContact CD2-CG 3.79Å; Y321-Y373 AromaticContact CE1-CD1 3.9Å; Y321-Y373 HydrophobicContact CE1-CD1 3.9Å; Y321-Y373 HydrophobicContact CE1-CE1 4.13Å; Y321-Y373 HydrophobicContact CE2-CD1 4.22Å; Y321-Y373 HydrophobicContact CE2-CG 4.45Å; Y321-Y373 AromaticContact CG-CD1 3.53Å; Y321-Y373 HydrophobicContact CG-CD1 3.53Å; Y321-Y373 HydrophobicContact CG-CD2 4.13Å; Y321-Y373 HydrophobicContact CG-CE1 4Å; Y321-Y373 AromaticContact CG-CG 3.58Å; Y321-Y373 HydrophobicContact CG-CG 3.58Å; Y324-Y373 VanDerWaalsContact CD1-OH 3.24Å; Y324-Y373 WeakPolarHBondContact CD1-OH 3.41Å; Y324-Y373 VanDerWaalsContact CE1-OH 3.28Å; Y324-Y373 WeakPolarHBondContact CE1-OH 3.32Å; E325-Y373 HydrophobicContact CG-CE2 3.57Å; E325-Y373 VanDerWaalsContact OE1-CE2 3.28Å; E325-Y373 WeakPolarHBondContact OE1-CE2 3.18Å; E325-Y373 PolarHBondContact OE1-OH 3.37Å; T369-Y373 HydrophobicContact CG2-CD2 4.06Å; T369-Y373 WeakPolarHBondContact O-CB 3.49Å; T369-Y373 WeakPolarHBondContact O-CD2 3.49Å; T369-Y373 PolarHBondContact O-N 3.25Å; Y373-L375 PolarHBondContact O-N 3.1Å; Y373-L484 HydrophobicContact CE1-CD1 4.31Å; Y373-Y486 WeakPolarHBondContact CE1-OH 3.41Å; Y373-L493 HydrophobicContact CD1-CD2 4.18Å
374T97Very high97.6Very high1 Ų114.9 Ų14.91%0.0068%0.078CC..  trans-72.196.6-178.3-52.40000110.6H53 L370 R371 V376 A407 C408 H411H53-T374 PolarHBondContact NE2-O 3.48Å; L370-T374 PolarHBondContact O-OG1 3.38Å; R371-T374 PolarHBondContact O-OG1 2.9Å; T374-V376 WeakPolarHBondContact CG2-O 3.29Å; T374-V376 PolarHBondContact O-N 3.24Å; T374-A407 HydrophobicContact CG2-CB 4.19Å; T374-C408 HydrophobicContact CG2-CB 4.43Å; T374-H411 PolarHBondContact OG1-ND1 3.18Å
375L95.5Very high97.6Very high14 Ų1418.5 Ų18.57%0.07310%0.097CC..SBendtrans-59.4-42.4-171.6-63180000113.9T314 T318 Y321 Y373 P377 V492 L493T314-L375 WeakPolarHBondContact O-CD1 3.44Å; T318-L375 WeakPolarHBondContact OG1-CD1 3.31Å; Y321-L375 HydrophobicContact CD2-CD2 4.1Å; Y321-L375 HydrophobicContact CE2-CD2 3.63Å; Y373-L375 PolarHBondContact O-N 3.1Å; L375-P377 WeakPolarHBondContact O-CD 3.1Å; L375-V492 CarbonylContact O-C 3.51Å; L375-V492 WeakPolarHBondContact O-CA 3.15Å; L375-V492 WeakPolarHBondContact O-CB 3.3Å; L375-L493 HydrophobicContact CD2-CB 4.4Å; L375-L493 PolarHBondContact O-N 3.49Å
376V95.3Very high97.6Very high59 Ų5923.7 Ų23.736%0.35813%0.125SC..SBendtrans-102.998.7171.8-179.10000107T374 H378 V492T374-V376 WeakPolarHBondContact CG2-O 3.29Å; T374-V376 PolarHBondContact O-N 3.24Å; V376-H378 WeakPolarHBondContact CG1-O 3.33Å; V376-H378 PolarHBondContact O-N 2.92Å; V376-V492 HydrophobicContact CG2-CG1 4.45Å
377P95.3Very high97.6Very high4 Ų424.4 Ų24.43%0.02613%0.128CC..  trans-69.6-20-164.226.2-34.7000113.6M52 F56 L375 A407 C408M52-P377 HydrophobicContact CB-CB 4.42Å; M52-P377 HydrophobicContact CB-CG 3.6Å; M52-P377 HydrophobicContact CE-CG 4.1Å; F56-P377 HydrophobicContact CD2-CB 4.22Å; F56-P377 HydrophobicContact CD2-CG 4.48Å; F56-P377 HydrophobicContact CE2-CG 4.35Å; L375-P377 WeakPolarHBondContact O-CD 3.1Å; P377-A407 PolarHBondContact O-N 3Å; P377-A407 VanDerWaalsContact O-N 3.15Å; P377-C408 HydrophobicContact CB-CB 3.9Å; P377-C408 WeakPolarHBondContact O-CB 3.35Å; P377-C408 PolarHBondContact O-N 2.85Å; P377-C408 PolarHBondContact O-SG 3.06Å
378H96.6Very high97.6Very high17 Ų1727.4 Ų27.48%0.07915%0.145CC..  trans-142.2153.1178.768.4-60.7000112.1F56 V376 E380 I404 I405F56-H378 HydrophobicContact CD2-CB 3.88Å; F56-H378 HydrophobicContact CE2-CB 3.62Å; F56-H378 AromaticContact CE2-CE1 3.83Å; F56-H378 AromaticContact CE2-CG 3.35Å; F56-H378 AromaticContact CE2-ND1 3.18Å; F56-H378 WeakPolarHBondContact CE2-ND1 3.49Å; F56-H378 HydrophobicContact CZ-CB 4.13Å; F56-H378 AromaticContact CZ-CD2 3.92Å; F56-H378 AromaticContact CZ-CE1 3.96Å; F56-H378 AromaticContact CZ-CG 3.64Å; F56-H378 AromaticContact CZ-ND1 3.7Å; V376-H378 WeakPolarHBondContact CG1-O 3.33Å; V376-H378 PolarHBondContact O-N 2.92Å; H378-E380 VanDerWaalsContact CD2-CG 3.47Å; H378-E380 WeakPolarHBondContact CD2-CG 3.25Å; H378-E380 IonicContact CD2-OE1 3.69Å; H378-E380 IonicContact CE1-OE1 3.43Å; H378-E380 WeakPolarHBondContact NE2-CG 3.23Å; H378-E380 IonicContact NE2-OE1 3.61Å; H378-E380 PolarHBondContact NE2-OE1 3.12Å; H378-I404 HydrophobicContact CB-CG2 3.99Å; H378-I405 CarbonylContact C-O 3.34Å; H378-I405 VanDerWaalsContact CA-O 3.23Å; H378-I405 WeakPolarHBondContact CA-O 3.47Å; H378-I405 WeakPolarHBondContact CB-O 3.23Å
379L97.8Very high97.5Very high20 Ų2027.5 Ų27.511%0.10515%0.146CC..EExtended strand (participates in β ladder)trans-101.8139.6168.6-49.7176.5000109.1L93 I405 L442L93-L379 HydrophobicContact CD1-CD1 3.98Å; L93-L379 HydrophobicContact CD2-CD1 4.1Å; L379-I405 HydrophobicContact CB-CB 4.23Å; L379-I405 PolarHBondContact N-O 3.27Å; L379-I405 PolarHBondContact O-N 3.11Å; L379-L442 HydrophobicContact CD1-CB 4.31Å; L379-L442 HydrophobicContact CD1-CD1 4.08Å; L379-L442 HydrophobicContact CD1-CD2 4.18Å; L379-L442 HydrophobicContact CD1-CG 4.45Å
380E96.1Very high97.3Very high28 Ų2830.9 Ų30.913%0.13117%0.167CC..EExtended strand (participates in β ladder)trans-109.7142.7177.4-65.6172.7158.200110.5Q105 H378 V403Q105-E380 PolarHBondContact NE2-OE2 3Å; H378-E380 VanDerWaalsContact CD2-CG 3.47Å; H378-E380 WeakPolarHBondContact CD2-CG 3.25Å; H378-E380 IonicContact CD2-OE1 3.69Å; H378-E380 IonicContact CE1-OE1 3.43Å; H378-E380 WeakPolarHBondContact NE2-CG 3.23Å; H378-E380 IonicContact NE2-OE1 3.61Å; H378-E380 PolarHBondContact NE2-OE1 3.12Å; E380-V403 CarbonylContact C-O 3.49Å; E380-V403 VanDerWaalsContact CA-O 3.3Å; E380-V403 WeakPolarHBondContact CA-O 3.35Å
381R97.9Very high97.2Very high3 Ų334.3 Ų34.31%0.01121%0.205CC..EExtended strand (participates in β ladder)trans-137172.6165.9-64.7-58-170.8-89.8-3.4110.1I92 L93 F100 D102 Q402 V403I92-R381 HydrophobicContact CG2-CB 4.23Å; I92-R381 HydrophobicContact CG2-CG 3.97Å; L93-R381 HydrophobicContact CD2-CG 4.48Å; L93-R381 VanDerWaalsContact CD2-NH2 3.28Å; F100-R381 HydrophobicContact CB-CB 4.09Å; F100-R381 HydrophobicContact CB-CG 4.28Å; F100-R381 HydrophobicContact CD1-CB 4.42Å; F100-R381 WeakPolarHBondContact O-CD 3.31Å; D102-R381 CarbonylContact O-C 3.58Å; D102-R381 VanDerWaalsContact O-CA 3.25Å; D102-R381 WeakPolarHBondContact O-CA 3.39Å; R381-Q402 PolarHBondContact O-NE2 2.89Å; R381-V403 HydrophobicContact CB-CB 4.08Å; R381-V403 PolarHBondContact N-O 3.46Å; R381-V403 PolarHBondContact O-N 3.29Å
382K97.5Very high97Very high51 Ų5137.8 Ų37.822%0.22222%0.221CC..EExtended strand (participates in β ladder)trans-137.3128.8173.9-177.2179.9176.6-173.10109.8D102 L384D102-K382 HydrophobicContact CB-CB 4.3Å; D102-K382 PolarHBondContact O-N 3.09Å; K382-L384 PolarHBondContact O-N 3.14Å
383A98.3Very high96.8Very high1 Ų146 Ų461%0.00826%0.26CS..  trans-65.9123.317500000110.2F100 I397 E398 G400 T401F100-A383 HydrophobicContact CD1-CB 4.32Å; F100-A383 HydrophobicContact CE1-CB 3.8Å; A383-I397 HydrophobicContact CB-CG2 3.93Å; A383-E398 WeakPolarHBondContact CB-O 3.49Å; A383-G400 WeakPolarHBondContact O-CA 3.39Å; A383-G400 PolarHBondContact O-N 2.95Å; A383-T401 PolarHBondContact N-O 2.87Å
384L98.1Very high96.6Very high51 Ų5154.9 Ų54.927%0.26730%0.299SS..SBendtrans-85.4-27.1178.3-63.1-174.7000112.2N99 A101 D102 K382 K399N99-L384 WeakPolarHBondContact O-CB 3.43Å; N99-L384 WeakPolarHBondContact O-CG 3.32Å; N99-L384 PolarHBondContact O-N 3.46Å; A101-L384 HydrophobicContact CB-CD1 4.26Å; D102-L384 HydrophobicContact CB-CD2 4Å; D102-L384 WeakPolarHBondContact OD2-CD2 2.87Å; K382-L384 PolarHBondContact O-N 3.14Å; L384-K399 VanDerWaalsContact O-CD 3.26Å; L384-K399 WeakPolarHBondContact O-CD 3.31Å; L384-K399 WeakPolarHBondContact O-CE 3.13Å; L384-K399 VanDerWaalsContact O-CG 3.3Å; L384-K399 WeakPolarHBondContact O-CG 3.38Å
385N98.4Very high96.6Very high90 Ų9055.6 Ų55.648%0.48130%0.302SS..SBendtrans-139.1164173.5-51.3-73.4000109.4N99 Y387N99-N385 PolarHBondContact ND2-O 3.27Å; N99-N385 WeakPolarHBondContact OD1-CA 3.34Å; N99-N385 VanDerWaalsContact OD1-CB 3.26Å; N99-N385 WeakPolarHBondContact OD1-CB 3.35Å; N99-N385 PolarHBondContact OD1-N 3.1Å; N99-N385 PolarHBondContact OD1-ND2 3.44Å; N99-N385 PolarHBondContact OD1-O 3.3Å; N385-Y387 PolarHBondContact O-N 3.43Å
386D98.4Very high96.7Very high109 Ų10957.2 Ų57.258%0.58331%0.312SS*.  trans-57.3132.6173.2-65.7-8.9000109.8V396 E398 K399D386-V396 HydrophobicContact CB-CG1 4.12Å; D386-E398 WeakPolarHBondContact OD1-CA 3.43Å; D386-K399 WeakPolarHBondContact OD1-CB 3.35Å; D386-K399 PolarHBondContact OD1-N 2.91Å
387Y98.4Very high96.8Very high21 Ų2154.4 Ų54.48%0.08230%0.295CS..EExtended strand (participates in β ladder)trans-124.2107.5-176.4-178.1-99.9000109.9L88 D96 F100 N385 V389 P390 V396 I397L88-Y387 HydrophobicContact CD1-CE1 3.86Å; D96-Y387 HydrophobicContact CB-CE2 3.88Å; D96-Y387 VanDerWaalsContact OD2-CE2 3.3Å; D96-Y387 WeakPolarHBondContact OD2-CE2 3.46Å; D96-Y387 PolarHBondContact OD2-OH 3.31Å; F100-Y387 HydrophobicContact CE2-CD1 4.15Å; F100-Y387 AromaticContact CE2-CD2 3.74Å; F100-Y387 HydrophobicContact CE2-CD2 3.74Å; F100-Y387 HydrophobicContact CE2-CE1 4.32Å; F100-Y387 AromaticContact CE2-CE2 3.92Å; F100-Y387 HydrophobicContact CE2-CE2 3.92Å; F100-Y387 AromaticContact CE2-CG 3.85Å; F100-Y387 HydrophobicContact CE2-CG 3.85Å; F100-Y387 AromaticContact CZ-CD1 3.76Å; F100-Y387 HydrophobicContact CZ-CD1 3.76Å; F100-Y387 AromaticContact CZ-CD2 3.95Å; F100-Y387 HydrophobicContact CZ-CD2 3.95Å; F100-Y387 HydrophobicContact CZ-CE1 4.29Å; F100-Y387 HydrophobicContact CZ-CE2 4.46Å; F100-Y387 AromaticContact CZ-CG 3.56Å; F100-Y387 HydrophobicContact CZ-CG 3.56Å; N385-Y387 PolarHBondContact O-N 3.43Å; Y387-V389 HydrophobicContact CD1-CG2 4.32Å; Y387-V389 HydrophobicContact CE1-CG2 4.35Å; Y387-V389 PolarHBondContact O-N 3.38Å; Y387-P390 WeakPolarHBondContact OH-CD 3.37Å; Y387-V396 CarbonylContact O-C 3.14Å; Y387-V396 WeakPolarHBondContact O-CA 3.49Å; Y387-I397 HydrophobicContact CD1-CD1 4.25Å; Y387-I397 PolarHBondContact N-O 2.77Å; Y387-I397 PolarHBondContact O-N 3.41Å
388V98.1Very high96.9Very high81 Ų8157 Ų5749%0.49131%0.307SS..EExtended strand (participates in β ladder)trans-73.4123170.7-1760000107.7P390 V396V388-P390 WeakPolarHBondContact O-CD 3.16Å; V388-V396 HydrophobicContact CG2-CG2 4.2Å
389V97.6Very high97Very high3 Ų362.8 Ų62.82%0.01833%0.332CS..EExtended strand (participates in β ladder)trans-68.4124.7-178.1176.20000109.7P69 F70 L88 Y387 G391 H392 L395 I397P69-V389 HydrophobicContact CB-CG1 4.18Å; P69-V389 HydrophobicContact CG-CG1 3.74Å; F70-V389 HydrophobicContact CD1-CG2 3.92Å; F70-V389 HydrophobicContact CE1-CG2 3.64Å; L88-V389 HydrophobicContact CD1-CG1 4.11Å; L88-V389 HydrophobicContact CD1-CG2 4.44Å; L88-V389 HydrophobicContact CD2-CG1 4.19Å; L88-V389 HydrophobicContact CD2-CG2 4.25Å; Y387-V389 HydrophobicContact CD1-CG2 4.32Å; Y387-V389 HydrophobicContact CE1-CG2 4.35Å; Y387-V389 PolarHBondContact O-N 3.38Å; V389-G391 PolarHBondContact O-N 3.02Å; V389-H392 HydrophobicContact CB-CB 4.17Å; V389-H392 HydrophobicContact CG1-CB 4.18Å; V389-H392 CarbonylContact O-C 3.37Å; V389-H392 WeakPolarHBondContact O-CA 3.48Å; V389-H392 PolarHBondContact O-N 3.47Å; V389-L395 HydrophobicContact CB-CB 4.33Å; V389-L395 HydrophobicContact CG2-CB 4.31Å; V389-L395 PolarHBondContact N-O 3.19Å; V389-I397 HydrophobicContact CG2-CD1 4.47Å; V389-I397 HydrophobicContact CG2-CG1 4.36Å
390P95.6Very high96.9Very high71 Ų7163.7 Ų63.746%0.46135%0.346SS..THydrogen-bonded Turntrans-54.8130178-28.136.3000111.7Y387 V388 H392Y387-P390 WeakPolarHBondContact OH-CD 3.37Å; V388-P390 WeakPolarHBondContact O-CD 3.16Å; P390-H392 VanDerWaalsContact C-N 3.25Å; P390-H392 PolarHBondContact O-N 2.97Å
391G94.8Very high96.9Very high82 Ų8262.9 Ų62.985%0.84534%0.343SS*.THydrogen-bonded Turntrans80.3-4.8-175.700000115.2V389V389-G391 PolarHBondContact O-N 3.02Å
392H95.1Very high96.8Very high73 Ų7364 Ų6434%0.33835%0.349SS..EExtended strand (participates in β ladder)trans-136.771.6-178.2-60.8-94000111.5V389 P390 K394 L395V389-H392 HydrophobicContact CB-CB 4.17Å; V389-H392 HydrophobicContact CG1-CB 4.18Å; V389-H392 CarbonylContact O-C 3.37Å; V389-H392 WeakPolarHBondContact O-CA 3.48Å; V389-H392 PolarHBondContact O-N 3.47Å; P390-H392 VanDerWaalsContact C-N 3.25Å; P390-H392 PolarHBondContact O-N 2.97Å; H392-K394 PolarHBondContact O-N 3.45Å; H392-L395 HydrophobicContact CB-CB 4.03Å; H392-L395 HydrophobicContact CB-CD1 3.82Å; H392-L395 HydrophobicContact CB-CG 4.03Å; H392-L395 PolarHBondContact O-N 3.45Å
393E93Very high96.9Very high175 Ų17561.6 Ų61.682%0.81834%0.338SS*.EExtended strand (participates in β ladder)trans-55.6-27.1-172.5-63176.817700115.2
394K93.3Very high96.9Very high199 Ų19961.6 Ų61.687%0.86534%0.338SS*.EExtended strand (participates in β ladder)trans-83.4-11178.7-63.9-178-179.5176.70113.5H392H392-K394 PolarHBondContact O-N 3.45Å
395L96.6Very high96.9Very high15 Ų1559.1 Ų59.18%0.07933%0.325CS..EExtended strand (participates in β ladder)trans-102.3113-178.3-61-176.3000109.6V31 F68 P69 F70 V389 H392V31-L395 HydrophobicContact CG2-CD2 4.3Å; F68-L395 HydrophobicContact CD1-CD1 3.91Å; F68-L395 HydrophobicContact CD1-CD2 4.26Å; F68-L395 HydrophobicContact CE1-CD2 4.29Å; P69-L395 HydrophobicContact CG-CD1 3.76Å; F70-L395 HydrophobicContact CE1-CB 3.89Å; F70-L395 HydrophobicContact CZ-CB 4.36Å; V389-L395 HydrophobicContact CB-CB 4.33Å; V389-L395 HydrophobicContact CG2-CB 4.31Å; V389-L395 PolarHBondContact N-O 3.19Å; H392-L395 HydrophobicContact CB-CB 4.03Å; H392-L395 HydrophobicContact CB-CD1 3.82Å; H392-L395 HydrophobicContact CB-CG 4.03Å; H392-L395 PolarHBondContact O-N 3.45Å
396V97.9Very high96.9Very high48 Ų4854.9 Ų54.929%0.29130%0.302SS..EExtended strand (participates in β ladder)trans-121.8125-178.6-175.50000109.7D386 Y387 V388 E398D386-V396 HydrophobicContact CB-CG1 4.12Å; Y387-V396 CarbonylContact O-C 3.14Å; Y387-V396 WeakPolarHBondContact O-CA 3.49Å; V388-V396 HydrophobicContact CG2-CG2 4.2Å; V396-E398 HydrophobicContact CG1-CG 4.49Å; V396-E398 PolarHBondContact O-N 2.77Å
397I98.3Very high96.9Very high0 Ų049.7 Ų49.70%027%0.274CS..EExtended strand (participates in β ladder)trans-86.1101.1165.4-54.7175.9000106.7F70 A81 I83 I92 A383 Y387 V389 T401 V403F70-I397 HydrophobicContact CD1-CD1 4.35Å; F70-I397 HydrophobicContact CD1-CG1 4.2Å; F70-I397 HydrophobicContact CE1-CD1 4.44Å; F70-I397 HydrophobicContact CE1-CG1 3.82Å; F70-I397 HydrophobicContact CZ-CG1 4.06Å; A81-I397 HydrophobicContact CB-CD1 4.27Å; A81-I397 HydrophobicContact CB-CG1 4.26Å; A81-I397 HydrophobicContact CB-CG2 4.28Å; I83-I397 HydrophobicContact CD1-CD1 4.3Å; I92-I397 HydrophobicContact CD1-CD1 4.19Å; A383-I397 HydrophobicContact CB-CG2 3.93Å; Y387-I397 HydrophobicContact CD1-CD1 4.25Å; Y387-I397 PolarHBondContact N-O 2.77Å; Y387-I397 PolarHBondContact O-N 3.41Å; V389-I397 HydrophobicContact CG2-CD1 4.47Å; V389-I397 HydrophobicContact CG2-CG1 4.36Å; I397-T401 HydrophobicContact CG2-CG2 4.17Å; I397-V403 HydrophobicContact CD1-CG2 4.49Å; I397-V403 HydrophobicContact CG2-CG2 4.03Å
398E97.7Very high96.8Very high59 Ų5948.7 Ų48.728%0.27627%0.271SS..  trans-67.1152.3-176.2-65.2175.7168.200112.3Y25 R29 A383 D386 V396 G400 T401Y25-E398 WeakPolarHBondContact CE2-OE2 3.21Å; Y25-E398 VanDerWaalsContact CZ-OE2 3.31Å; Y25-E398 VanDerWaalsContact OH-CD 3.32Å; Y25-E398 PolarHBondContact OH-OE2 3.47Å; R29-E398 IonicContact CZ-OE1 3.94Å; R29-E398 IonicContact CZ-OE2 2.64Å; R29-E398 VanDerWaalsContact CZ-OE2 3.25Å; R29-E398 IonicContact NE-OE1 2.73Å; R29-E398 PolarHBondContact NE-OE1 3.44Å; R29-E398 IonicContact NE-OE2 2.76Å; R29-E398 PolarHBondContact NE-OE2 3.41Å; R29-E398 IonicContact NH2-OE1 3.22Å; R29-E398 PolarHBondContact NH2-OE1 2.83Å; R29-E398 IonicContact NH2-OE2 2.67Å; R29-E398 PolarHBondContact NH2-OE2 3.31Å; A383-E398 WeakPolarHBondContact CB-O 3.49Å; D386-E398 WeakPolarHBondContact OD1-CA 3.43Å; V396-E398 HydrophobicContact CG1-CG 4.49Å; V396-E398 PolarHBondContact O-N 2.77Å; E398-G400 PolarHBondContact O-N 3.42Å; E398-T401 WeakPolarHBondContact O-CB 3.38Å; E398-T401 PolarHBondContact O-N 3.02Å; E398-T401 PolarHBondContact O-OG1 2.91Å
399K97.8Very high96.8Very high139 Ų13944.8 Ų44.860%0.60425%0.247SC*.THydrogen-bonded Turntrans-48.3131.1172.5175.7167.7-175.5164.10111.8L384 D386 T401L384-K399 VanDerWaalsContact O-CD 3.26Å; L384-K399 WeakPolarHBondContact O-CD 3.31Å; L384-K399 WeakPolarHBondContact O-CE 3.13Å; L384-K399 VanDerWaalsContact O-CG 3.3Å; L384-K399 WeakPolarHBondContact O-CG 3.38Å; D386-K399 WeakPolarHBondContact OD1-CB 3.35Å; D386-K399 PolarHBondContact OD1-N 2.91Å; K399-T401 VanDerWaalsContact C-N 3.25Å; K399-T401 PolarHBondContact O-N 3.37Å
400G95.1Very high96.9Very high39 Ų3944.7 Ų44.740%0.40225%0.246SC..THydrogen-bonded Turntrans84.4-7.3179.100000114.3A383 E398A383-G400 WeakPolarHBondContact O-CA 3.39Å; A383-G400 PolarHBondContact O-N 2.95Å; E398-G400 PolarHBondContact O-N 3.42Å
401T96.8Very high97Very high10 Ų1041.3 Ų41.36%0.06122%0.224CC..  trans-66.6132175.2-550000110.2Y25 W26 A81 A383 I397 E398 K399Y25-T401 PolarHBondContact OH-OG1 2.69Å; W26-T401 HydrophobicContact CH2-CG2 4.03Å; W26-T401 HydrophobicContact CZ2-CG2 4.15Å; A81-T401 HydrophobicContact CB-CG2 4.31Å; A383-T401 PolarHBondContact N-O 2.87Å; I397-T401 HydrophobicContact CG2-CG2 4.17Å; E398-T401 WeakPolarHBondContact O-CB 3.38Å; E398-T401 PolarHBondContact O-N 3.02Å; E398-T401 PolarHBondContact O-OG1 2.91Å; K399-T401 VanDerWaalsContact C-N 3.25Å; K399-T401 PolarHBondContact O-N 3.37Å
402Q96.6Very high97.2Very high27 Ų2738.9 Ų38.913%0.12619%0.19CC..EExtended strand (participates in β ladder)trans-72141.4172.9-160.273.126.700108.8A80 A81 R103 R381A80-Q402 CarbonylContact C-O 3.55Å; A80-Q402 WeakPolarHBondContact CA-O 3.27Å; A80-Q402 HydrophobicContact CB-CB 3.92Å; A81-Q402 PolarHBondContact N-O 3.45Å; R103-Q402 PolarHBondContact O-NE2 3.4Å; R381-Q402 PolarHBondContact O-NE2 2.89Å
403V98.4Very high97.3Very high0 Ų035.8 Ų35.80%018%0.175CC..EExtended strand (participates in β ladder)trans-117.5132.6177173.80000108.2A81 I83 I92 F100 E380 R381 I397 I405A81-V403 HydrophobicContact CB-CG2 4.4Å; A81-V403 CarbonylContact O-C 3.56Å; A81-V403 WeakPolarHBondContact O-CA 3.23Å; I83-V403 HydrophobicContact CD1-CG1 3.78Å; I83-V403 HydrophobicContact CG1-CG1 3.53Å; I92-V403 HydrophobicContact CD1-CG1 3.96Å; I92-V403 HydrophobicContact CG2-CG1 4.28Å; F100-V403 HydrophobicContact CD1-CG2 4.22Å; F100-V403 HydrophobicContact CE1-CG2 3.97Å; E380-V403 CarbonylContact C-O 3.49Å; E380-V403 VanDerWaalsContact CA-O 3.3Å; E380-V403 WeakPolarHBondContact CA-O 3.35Å; R381-V403 HydrophobicContact CB-CB 4.08Å; R381-V403 PolarHBondContact N-O 3.46Å; R381-V403 PolarHBondContact O-N 3.29Å; I397-V403 HydrophobicContact CD1-CG2 4.49Å; I397-V403 HydrophobicContact CG2-CG2 4.03Å; V403-I405 HydrophobicContact CG1-CG1 4.34Å
404I98.1Very high97.5Very high1 Ų132 Ų321%0.00516%0.158CC..EExtended strand (participates in β ladder)trans-118.5121.8178.2-63.4172.1000108.1F56 F73 F75 A80 A81 F82 I83 H378F56-I404 HydrophobicContact CD1-CG2 4.46Å; F56-I404 HydrophobicContact CE1-CG2 4.11Å; F56-I404 HydrophobicContact CZ-CG2 4.45Å; F73-I404 HydrophobicContact CD1-CD1 3.59Å; F73-I404 HydrophobicContact CE1-CD1 3.81Å; F75-I404 HydrophobicContact CB-CD1 4.38Å; F75-I404 HydrophobicContact CD2-CD1 4.17Å; A80-I404 HydrophobicContact CB-CD1 3.69Å; A80-I404 HydrophobicContact CB-CG1 4.08Å; A81-I404 PolarHBondContact O-N 3.49Å; F82-I404 HydrophobicContact CD2-CB 4.1Å; F82-I404 HydrophobicContact CD2-CG2 3.73Å; F82-I404 HydrophobicContact CE2-CG2 3.94Å; I83-I404 PolarHBondContact N-O 3.12Å; H378-I404 HydrophobicContact CB-CG2 3.99Å
405I98.7Very high97.6Very high0 Ų027.5 Ų27.50%014%0.143CC..EExtended strand (participates in β ladder)trans-108.5111.1173.2-61159.6000107.1I83 A89 I92 L93 H378 L379 V403 A407 Y410 L442I83-I405 HydrophobicContact CB-CG1 4.12Å; I83-I405 HydrophobicContact CG1-CG1 3.87Å; A89-I405 HydrophobicContact CB-CD1 4.43Å; A89-I405 HydrophobicContact CB-CG1 4.41Å; A89-I405 HydrophobicContact CB-CG2 3.99Å; I92-I405 HydrophobicContact CG2-CD1 4.13Å; L93-I405 HydrophobicContact CD1-CD1 3.96Å; L93-I405 HydrophobicContact CD2-CD1 3.54Å; L93-I405 HydrophobicContact CG-CD1 3.61Å; H378-I405 CarbonylContact C-O 3.34Å; H378-I405 VanDerWaalsContact CA-O 3.23Å; H378-I405 WeakPolarHBondContact CA-O 3.47Å; H378-I405 WeakPolarHBondContact CB-O 3.23Å; L379-I405 HydrophobicContact CB-CB 4.23Å; L379-I405 PolarHBondContact N-O 3.27Å; L379-I405 PolarHBondContact O-N 3.11Å; V403-I405 HydrophobicContact CG1-CG1 4.34Å; I405-A407 VanDerWaalsContact C-N 3.33Å; I405-A407 PolarHBondContact O-N 3.02Å; I405-Y410 HydrophobicContact CG2-CD2 4.42Å; I405-Y410 HydrophobicContact CG2-CE2 3.65Å; I405-L442 HydrophobicContact CG2-CD1 3.89Å
406P98Very high97.6Very high0 Ų028.7 Ų28.70%015%0.15CC..  trans-81.674.9-171.435.9-38.6000111.5F56 Y60 F82 I83 C408 A409 Y410F56-P406 HydrophobicContact CB-CB 4.01Å; Y60-P406 HydrophobicContact CD2-CG 3.98Å; F82-P406 HydrophobicContact CE1-CB 4.2Å; F82-P406 HydrophobicContact CE1-CG 3.73Å; F82-P406 HydrophobicContact CE2-CB 3.81Å; F82-P406 HydrophobicContact CE2-CG 4.12Å; F82-P406 HydrophobicContact CZ-CB 3.41Å; F82-P406 VanDerWaalsContact CZ-CB 3.41Å; F82-P406 HydrophobicContact CZ-CG 3.47Å; F82-P406 VanDerWaalsContact CZ-CG 3.47Å; I83-P406 WeakPolarHBondContact O-CD 3.33Å; I83-P406 WeakPolarHBondContact O-CG 3.12Å; P406-C408 PolarHBondContact O-N 3.22Å; P406-A409 HydrophobicContact CB-CB 3.88Å; P406-A409 HydrophobicContact CG-CB 4.23Å; P406-A409 WeakPolarHBondContact O-CA 3.43Å; P406-A409 WeakPolarHBondContact O-CB 3.37Å; P406-A409 PolarHBondContact O-N 3.18Å; P406-Y410 HydrophobicContact CG-CD1 4.12Å; P406-Y410 HydrophobicContact CG-CE1 3.67Å; P406-Y410 PolarHBondContact O-N 2.87Å
407A98.4Very high97.6Very high0 Ų026.5 Ų26.50%014%0.136CC..Hα-helixtrans-49.6-44.5-179.500000112.9T374 P377 I405 A409 Y410 H411 L442T374-A407 HydrophobicContact CG2-CB 4.19Å; P377-A407 PolarHBondContact O-N 3Å; P377-A407 VanDerWaalsContact O-N 3.15Å; I405-A407 VanDerWaalsContact C-N 3.33Å; I405-A407 PolarHBondContact O-N 3.02Å; A407-A409 PolarHBondContact O-N 3.38Å; A407-Y410 PolarHBondContact O-N 2.64Å; A407-H411 WeakPolarHBondContact O-CB 3.45Å; A407-H411 PolarHBondContact O-CD2 3.49Å; A407-H411 VanDerWaalsContact O-CD2 3.24Å; A407-H411 PolarHBondContact O-N 2.97Å; A407-L442 HydrophobicContact CB-CB 3.85Å; A407-L442 HydrophobicContact CB-CD1 4.45Å
408C97.8Very high97.5Very high0 Ų030.3 Ų30.30%016%0.161CC..Hα-helixtrans-57.5-34.8176.257.20000114.4H53 T374 P377 P406H53-C408 WeakPolarHBondContact CE1-CB 3.34Å; H53-C408 WeakPolarHBondContact ND1-CB 2.88Å; H53-C408 VanDerWaalsContact NE2-CB 3.26Å; H53-C408 WeakPolarHBondContact NE2-CB 3.04Å; T374-C408 HydrophobicContact CG2-CB 4.43Å; P377-C408 HydrophobicContact CB-CB 3.9Å; P377-C408 WeakPolarHBondContact O-CB 3.35Å; P377-C408 PolarHBondContact O-N 2.85Å; P377-C408 PolarHBondContact O-SG 3.06Å; P406-C408 PolarHBondContact O-N 3.22Å
409A98.1Very high97.4Very high0 Ų033.3 Ų33.30%018%0.179CC..Hα-helixtrans-80.1-40.3-178.500000110.8Y57 Y60 P406 A407 H411 R412 D413Y57-A409 HydrophobicContact CD2-CB 4.47Å; Y60-A409 VanDerWaalsContact CB-CB 3.47Å; Y60-A409 HydrophobicContact CD1-CB 3.59Å; Y60-A409 HydrophobicContact CD2-CB 4.31Å; Y60-A409 HydrophobicContact CE1-CB 4.4Å; Y60-A409 HydrophobicContact CG-CB 3.52Å; P406-A409 HydrophobicContact CB-CB 3.88Å; P406-A409 HydrophobicContact CG-CB 4.23Å; P406-A409 WeakPolarHBondContact O-CA 3.43Å; P406-A409 WeakPolarHBondContact O-CB 3.37Å; P406-A409 PolarHBondContact O-N 3.18Å; A407-A409 PolarHBondContact O-N 3.38Å; A409-H411 VanDerWaalsContact C-N 3.26Å; A409-H411 PolarHBondContact O-N 3.42Å; A409-R412 CarbonylContact O-C 3.6Å; A409-R412 PolarHBondContact O-N 3.01Å; A409-D413 PolarHBondContact O-N 3.43Å
410Y98.4Very high97.4Very high0 Ų027.5 Ų27.50%016%0.155CC..Hα-helixtrans-58.9-42173-65.5-0.3000111Y60 I83 T86 A89 I405 P406 A407 R412 D413 Y417 L442Y60-Y410 HydrophobicContact CD2-CD1 4.33Å; Y60-Y410 HydrophobicContact CD2-CE1 4.08Å; Y60-Y410 AromaticContact CE2-CD1 3.74Å; Y60-Y410 HydrophobicContact CE2-CD1 3.74Å; Y60-Y410 AromaticContact CE2-CE1 3.49Å; Y60-Y410 HydrophobicContact CE2-CE1 3.49Å; Y60-Y410 VanDerWaalsContact CE2-CE1 3.49Å; Y60-Y410 AromaticContact CZ-CD1 3.85Å; I83-Y410 PolarHBondContact O-OH 3.15Å; T86-Y410 HydrophobicContact CG2-CD2 4.04Å; T86-Y410 HydrophobicContact CG2-CE2 3.95Å; T86-Y410 HydrophobicContact CG2-CG 4.35Å; A89-Y410 HydrophobicContact CB-CE2 3.98Å; I405-Y410 HydrophobicContact CG2-CD2 4.42Å; I405-Y410 HydrophobicContact CG2-CE2 3.65Å; P406-Y410 HydrophobicContact CG-CD1 4.12Å; P406-Y410 HydrophobicContact CG-CE1 3.67Å; P406-Y410 PolarHBondContact O-N 2.87Å; A407-Y410 PolarHBondContact O-N 2.64Å; Y410-R412 PolarHBondContact O-N 3.47Å; Y410-R412 VanDerWaalsContact O-N 3.13Å; Y410-D413 PolarHBondContact O-N 2.88Å; Y410-Y417 WeakPolarHBondContact O-CD2 3.43Å; Y410-Y417 WeakPolarHBondContact O-CE2 3.44Å; Y410-L442 HydrophobicContact CD2-CD1 3.98Å; Y410-L442 HydrophobicContact CE2-CD1 4.28Å
411H98.6Very high97.5Very high0 Ų030.8 Ų30.80%016%0.16CC..THydrogen-bonded Turntrans-65.4-14.9177.8-69.4-178.1000114.1R371 T374 A407 A409 E440 L442R371-H411 HydrophobicContact CG-CB 3.75Å; R371-H411 WeakPolarHBondContact CG-O 3.39Å; R371-H411 PolarHBondContact NH1-O 3.37Å; R371-H411 WeakPolarHBondContact O-CB 3.28Å; R371-H411 PolarHBondContact O-ND1 3.05Å; T374-H411 PolarHBondContact OG1-ND1 3.18Å; A407-H411 WeakPolarHBondContact O-CB 3.45Å; A407-H411 PolarHBondContact O-CD2 3.49Å; A407-H411 VanDerWaalsContact O-CD2 3.24Å; A407-H411 PolarHBondContact O-N 2.97Å; A409-H411 VanDerWaalsContact C-N 3.26Å; A409-H411 PolarHBondContact O-N 3.42Å; H411-E440 PolarHBondContact CD2-O 3.41Å; H411-L442 PolarHBondContact NE2-N 3.14Å
412R97.6Very high97.5Very high32 Ų3234.1 Ų34.112%0.12118%0.18CC..THydrogen-bonded Turntrans-121.314.8179.7-66.2175.2174-102.9-2.9112.4Y57 L372 A409 Y410 E414 P420 E421Y57-R412 HydrophobicContact CD2-CB 4Å; Y57-R412 HydrophobicContact CE2-CB 3.51Å; L372-R412 PolarHBondContact O-NE 3.16Å; L372-R412 PolarHBondContact O-NH2 2.85Å; A409-R412 CarbonylContact O-C 3.6Å; A409-R412 PolarHBondContact O-N 3.01Å; Y410-R412 PolarHBondContact O-N 3.47Å; Y410-R412 VanDerWaalsContact O-N 3.13Å; R412-E414 PolarHBondContact O-N 2.81Å; R412-P420 HydrophobicContact CB-CB 4.32Å; R412-P420 WeakPolarHBondContact O-CB 3.48Å; R412-P420 WeakPolarHBondContact O-CG 3.41Å; R412-E421 IonicContact CZ-OE1 3.41Å; R412-E421 IonicContact CZ-OE2 3.07Å; R412-E421 IonicContact NH1-OE1 3.47Å; R412-E421 PolarHBondContact NH1-OE1 2.76Å; R412-E421 IonicContact NH1-OE2 2.77Å; R412-E421 PolarHBondContact NH1-OE2 3.05Å
413D97.6Very high97.6Very high7 Ų733.3 Ų33.34%0.03718%0.177CC..  trans-74.3122.1172.4-171.8-8.2000108.8Y60 R64 A409 Y410 D415 L416 Y417Y60-D413 HydrophobicContact CE1-CB 4.04Å; Y60-D413 PolarHBondContact OH-OD2 3.32Å; R64-D413 IonicContact CZ-OD1 3.79Å; R64-D413 IonicContact NE-OD1 3.64Å; R64-D413 PolarHBondContact NE-OD1 3.34Å; R64-D413 IonicContact NE-OD2 2.66Å; R64-D413 IonicContact NH1-OD1 2.71Å; R64-D413 PolarHBondContact NH1-OD1 2.9Å; R64-D413 IonicContact NH2-OD1 3.84Å; R64-D413 PolarHBondContact NH2-OD1 2.79Å; A409-D413 PolarHBondContact O-N 3.43Å; Y410-D413 PolarHBondContact O-N 2.88Å; D413-D415 PolarHBondContact O-N 2.79Å; D413-D415 PolarHBondContact OD1-N 3.48Å; D413-L416 HydrophobicContact CB-CB 4.21Å; D413-L416 HydrophobicContact CB-CD1 4.06Å; D413-L416 HydrophobicContact CB-CG 4.01Å; D413-L416 PolarHBondContact O-N 2.8Å; D413-Y417 WeakPolarHBondContact O-CA 3.36Å; D413-Y417 PolarHBondContact O-N 3.47Å
414E96.9Very high97.6Very high95 Ų9535.6 Ų35.644%0.44419%0.189SC..THydrogen-bonded Turntrans-65.2-24.5178.169.4-169.1165.300112.8R64 K65 R412 L416 Y417 P418 P420R64-E414 IonicContact CZ-OE1 3.48Å; R64-E414 IonicContact NH1-OE1 2.64Å; R64-E414 IonicContact NH2-OE1 3.22Å; R64-E414 PolarHBondContact NH2-OE1 2.58Å; K65-E414 IonicContact NZ-OE1 2.71Å; R412-E414 PolarHBondContact O-N 2.81Å; E414-L416 VanDerWaalsContact C-N 3.32Å; E414-Y417 CarbonylContact O-C 3.49Å; E414-P418 WeakPolarHBondContact O-CA 3.26Å; E414-P420 HydrophobicContact CB-CG 4.27Å
415D95.8Very high97.6Very high105 Ų10535.7 Ų35.756%0.56119%0.189SC*.THydrogen-bonded Turntrans-74-28.2177.7-62.1-37.1000110.8R64 D413R64-D415 IonicContact CZ-OD2 2.64Å; R64-D415 IonicContact NE-OD2 3.12Å; R64-D415 PolarHBondContact NE-OD2 3.06Å; R64-D415 VanDerWaalsContact NH2-CG 3.34Å; R64-D415 IonicContact NH2-OD1 3.51Å; R64-D415 IonicContact NH2-OD2 2.62Å; R64-D415 PolarHBondContact NH2-OD2 2.7Å; D413-D415 PolarHBondContact O-N 2.79Å; D413-D415 PolarHBondContact OD1-N 3.48Å
416L96.6Very high97.6Very high41 Ų4138.7 Ų38.722%0.21520%0.203CC..THydrogen-bonded Turntrans-94.2-35.9176.4-57.2-179.6000112.3T86 D413 E414 E440T86-L416 HydrophobicContact CG2-CD1 4.07Å; D413-L416 HydrophobicContact CB-CB 4.21Å; D413-L416 HydrophobicContact CB-CD1 4.06Å; D413-L416 HydrophobicContact CB-CG 4.01Å; D413-L416 PolarHBondContact O-N 2.8Å; E414-L416 VanDerWaalsContact C-N 3.32Å; L416-E440 HydrophobicContact CD1-CB 4.24Å; L416-E440 HydrophobicContact CD1-CG 4.11Å; L416-E440 HydrophobicContact CD2-CG 4.09Å
417Y97.4Very high97.6Very high2 Ų239.7 Ų39.71%0.00821%0.207CC..SBendtrans-134.887.8-175.8-59.3-81.1000110.1R371 Y410 D413 E414 N419 P420 E440 W441R371-Y417 VanDerWaalsContact CD-CD1 3.43Å; R371-Y417 VanDerWaalsContact CD-CE1 3.49Å; R371-Y417 HydrophobicContact CG-CE1 4.34Å; Y410-Y417 WeakPolarHBondContact O-CD2 3.43Å; Y410-Y417 WeakPolarHBondContact O-CE2 3.44Å; D413-Y417 WeakPolarHBondContact O-CA 3.36Å; D413-Y417 PolarHBondContact O-N 3.47Å; E414-Y417 CarbonylContact O-C 3.49Å; Y417-N419 PolarHBondContact O-N 3.07Å; Y417-P420 WeakPolarHBondContact O-CA 3.32Å; Y417-P420 WeakPolarHBondContact O-CB 3.38Å; Y417-P420 VanDerWaalsContact O-CD 3.31Å; Y417-P420 WeakPolarHBondContact O-CD 3.42Å; Y417-E440 WeakPolarHBondContact CE2-O 3.47Å; Y417-E440 PolarHBondContact OH-O 3.37Å; Y417-W441 WeakPolarHBondContact OH-CB 3.4Å
418P96.4Very high97.6Very high79 Ų7940.2 Ų40.251%0.51321%0.21SC..SBendtrans-56.9135.2-179.9-26.634.6000111.9E414 R427E414-P418 WeakPolarHBondContact O-CA 3.26Å; P418-R427 PolarHBondContact O-NH1 2.61Å; P418-R427 PolarHBondContact O-NH2 2.98Å
419N97.4Very high97.6Very high122 Ų12240.9 Ų40.965%0.65221%0.214SC*.SBendtrans55.260.9-168.4-53.8-51.7000112.3Y417 E421 T422 R427Y417-N419 PolarHBondContact O-N 3.07Å; N419-E421 PolarHBondContact O-N 3.49Å; N419-E421 VanDerWaalsContact O-N 3.08Å; N419-T422 PolarHBondContact O-N 2.94Å; N419-T422 VanDerWaalsContact O-N 3.08Å; N419-R427 PolarHBondContact O-NH2 3.47Å
420P97.2Very high97.5Very high18 Ų1844.4 Ų44.412%0.11724%0.237CC..THydrogen-bonded Turntrans-65.8-17.2-166.624.4-33.7000114.3R371 L372 R412 E414 Y417R371-P420 VanDerWaalsContact CZ-O 3.27Å; R371-P420 PolarHBondContact NH1-O 2.76Å; R371-P420 PolarHBondContact NH2-O 2.77Å; L372-P420 VanDerWaalsContact CD2-O 3.26Å; L372-P420 WeakPolarHBondContact CD2-O 3.31Å; R412-P420 HydrophobicContact CB-CB 4.32Å; R412-P420 WeakPolarHBondContact O-CB 3.48Å; R412-P420 WeakPolarHBondContact O-CG 3.41Å; E414-P420 HydrophobicContact CB-CG 4.27Å; Y417-P420 WeakPolarHBondContact O-CA 3.32Å; Y417-P420 WeakPolarHBondContact O-CB 3.38Å; Y417-P420 VanDerWaalsContact O-CD 3.31Å; Y417-P420 WeakPolarHBondContact O-CD 3.42Å
421E96.3Very high97.5Very high108 Ų10850.7 Ų50.751%0.50527%0.266SS..THydrogen-bonded Turntrans-85.1-12.2178.7-61.6-58.1136.300113.4R412 N419R412-E421 IonicContact CZ-OE1 3.41Å; R412-E421 IonicContact CZ-OE2 3.07Å; R412-E421 IonicContact NH1-OE1 3.47Å; R412-E421 PolarHBondContact NH1-OE1 2.76Å; R412-E421 IonicContact NH1-OE2 2.77Å; R412-E421 PolarHBondContact NH1-OE2 3.05Å; N419-E421 PolarHBondContact O-N 3.49Å; N419-E421 VanDerWaalsContact O-N 3.08Å
422T97.7Very high97.4Very high79 Ų7955.3 Ų55.349%0.48529%0.286SS..SBendtrans-83.8130.2-179.7-54.70000110.8R371 N419 D424R371-T422 PolarHBondContact NH2-O 3.08Å; R371-T422 VanDerWaalsContact NH2-O 3.17Å; N419-T422 PolarHBondContact O-N 2.94Å; N419-T422 VanDerWaalsContact O-N 3.08Å; T422-D424 PolarHBondContact O-N 2.98Å
423F98.6Very high97.4Very high11 Ų1157.1 Ų57.15%0.04830%0.301CS..  trans-73.698.4171.8-171.5-93.2000110.1E325 I332 V365 E368 L372 P425E325-F423 HydrophobicContact CB-CD1 4.24Å; E325-F423 HydrophobicContact CB-CD2 3.67Å; E325-F423 HydrophobicContact CB-CE1 4.23Å; E325-F423 HydrophobicContact CB-CE2 3.7Å; E325-F423 HydrophobicContact CB-CG 4Å; E325-F423 HydrophobicContact CB-CZ 3.99Å; E325-F423 HydrophobicContact CG-CD2 3.48Å; E325-F423 VanDerWaalsContact CG-CD2 3.48Å; E325-F423 HydrophobicContact CG-CE2 3.77Å; E325-F423 HydrophobicContact CG-CG 4.11Å; I332-F423 HydrophobicContact CD1-CD1 3.74Å; I332-F423 HydrophobicContact CD1-CE1 4.16Å; I332-F423 HydrophobicContact CG2-CE1 4.22Å; V365-F423 HydrophobicContact CG1-CE1 4.37Å; V365-F423 HydrophobicContact CG1-CZ 3.93Å; E368-F423 HydrophobicContact CB-CE2 4.17Å; E368-F423 HydrophobicContact CB-CZ 4.36Å; E368-F423 HydrophobicContact CG-CD2 3.76Å; E368-F423 HydrophobicContact CG-CE2 3.79Å; E368-F423 HydrophobicContact CG-CG 4.11Å; E368-F423 HydrophobicContact CG-CZ 4.22Å; L372-F423 HydrophobicContact CD1-CB 3.81Å; L372-F423 HydrophobicContact CD1-CD2 3.54Å; L372-F423 HydrophobicContact CD1-CG 4.14Å; F423-P425 HydrophobicContact CD1-CG 4.3Å; F423-P425 HydrophobicContact CE1-CG 3.81Å; F423-P425 HydrophobicContact CZ-CG 4.49Å
424D98.6Very high97.4Very high48 Ų4861 Ų6126%0.25733%0.333SS..  trans-126.997.5-178.717518.9000111.5E368 T422 E426 R427E368-D424 VanDerWaalsContact CD-O 3.31Å; E368-D424 PolarHBondContact OE1-N 2.87Å; T422-D424 PolarHBondContact O-N 2.98Å; D424-E426 PolarHBondContact O-N 2.82Å; D424-E426 VanDerWaalsContact OD1-CB 3.24Å; D424-E426 WeakPolarHBondContact OD1-CB 3.47Å; D424-E426 PolarHBondContact OD1-N 3.43Å; D424-R427 HydrophobicContact CB-CG 4.17Å; D424-R427 WeakPolarHBondContact O-CB 3.29Å; D424-R427 WeakPolarHBondContact O-CG 3.34Å; D424-R427 PolarHBondContact O-N 2.83Å
425P98.7Very high97.3Very high2 Ų260.8 Ų60.81%0.01335%0.348CS..G310 helixtrans-56.8-27.9175.6-27.136.2000114I332 Y361 Q364 V365 F423 R427 F428I332-P425 HydrophobicContact CD1-CG 4.2Å; I332-P425 HydrophobicContact CG2-CG 3.91Å; Y361-P425 HydrophobicContact CE2-CB 3.85Å; Q364-P425 HydrophobicContact CB-CB 3.99Å; Q364-P425 WeakPolarHBondContact CB-O 3.46Å; V365-P425 HydrophobicContact CG2-CB 4.06Å; V365-P425 HydrophobicContact CG2-CG 3.84Å; F423-P425 HydrophobicContact CD1-CG 4.3Å; F423-P425 HydrophobicContact CE1-CG 3.81Å; F423-P425 HydrophobicContact CZ-CG 4.49Å; P425-R427 PolarHBondContact O-N 3.06Å; P425-F428 PolarHBondContact O-N 2.83Å
426E98.1Very high97.4Very high63 Ų6357.8 Ų57.829%0.29433%0.329SS..G310 helixtrans-65.9-12.7-178.5-64.6-61.9147.300112.7R335 D424 F428 S429 K432R335-E426 IonicContact CZ-OE1 3.91Å; R335-E426 IonicContact NH1-OE1 2.69Å; R335-E426 PolarHBondContact NH1-OE1 3.02Å; R335-E426 IonicContact NH2-OE1 2.55Å; R335-E426 PolarHBondContact NH2-OE1 2.98Å; D424-E426 PolarHBondContact O-N 2.82Å; D424-E426 VanDerWaalsContact OD1-CB 3.24Å; D424-E426 WeakPolarHBondContact OD1-CB 3.47Å; D424-E426 PolarHBondContact OD1-N 3.43Å; E426-F428 PolarHBondContact O-N 2.87Å; E426-S429 PolarHBondContact O-N 2.66Å; E426-K432 VanDerWaalsContact O-CD 3.27Å; E426-K432 WeakPolarHBondContact O-CD 3.21Å; E426-K432 WeakPolarHBondContact O-CE 3.08Å; E426-K432 PolarHBondContact O-NZ 3.33Å
427R97.9Very high97.4Very high21 Ų2159.6 Ų59.68%0.07934%0.336CS..G310 helixtrans-60.6-22.3168-65178.2-166.6-73-3.7112.5E368 P418 N419 D424 P425 K432 R436E368-R427 IonicContact OE1-NE 3.38Å; P418-R427 PolarHBondContact O-NH1 2.61Å; P418-R427 PolarHBondContact O-NH2 2.98Å; N419-R427 PolarHBondContact O-NH2 3.47Å; D424-R427 HydrophobicContact CB-CG 4.17Å; D424-R427 WeakPolarHBondContact O-CB 3.29Å; D424-R427 WeakPolarHBondContact O-CG 3.34Å; D424-R427 PolarHBondContact O-N 2.83Å; P425-R427 PolarHBondContact O-N 3.06Å; R427-K432 WeakPolarHBondContact O-CB 3.39Å; R427-R436 PolarHBondContact O-NH2 3.23Å
428F98.4Very high97.3Very high12 Ų1262.3 Ų62.35%0.05336%0.356CS..G310 helixtrans-108.819.5-177.1-69.5-85.3000113.1Q364 S367 E368 R371 P425 E426 V433 W441Q364-F428 HydrophobicContact CB-CB 4.15Å; Q364-F428 HydrophobicContact CG-CB 4.09Å; Q364-F428 WeakPolarHBondContact CG-O 3.35Å; S367-F428 VanDerWaalsContact CB-CG 3.45Å; E368-F428 HydrophobicContact CB-CD2 4Å; E368-F428 HydrophobicContact CB-CE2 4.14Å; E368-F428 VanDerWaalsContact OE2-CE2 3.26Å; E368-F428 WeakPolarHBondContact OE2-CE2 3.25Å; R371-F428 HydrophobicContact CB-CE2 4.17Å; R371-F428 HydrophobicContact CB-CZ 4.08Å; P425-F428 PolarHBondContact O-N 2.83Å; E426-F428 PolarHBondContact O-N 2.87Å; F428-V433 HydrophobicContact CB-CG2 4.24Å; F428-V433 HydrophobicContact CD1-CG2 3.98Å; F428-W441 AromaticContact CE1-CD1 3.48Å; F428-W441 VanDerWaalsContact CE1-CD1 3.48Å; F428-W441 AromaticContact CE1-CD2 3.87Å; F428-W441 HydrophobicContact CE1-CD2 3.87Å; F428-W441 AromaticContact CE1-CE2 3.56Å; F428-W441 AromaticContact CE1-CG 3.77Å; F428-W441 HydrophobicContact CE1-CG 3.77Å; F428-W441 HydrophobicContact CE1-CZ2 4.24Å; F428-W441 AromaticContact CE1-NE1 3.32Å; F428-W441 VanDerWaalsContact CE1-NE1 3.32Å; F428-W441 AromaticContact CZ-CD1 3.34Å; F428-W441 HydrophobicContact CZ-CD2 4.45Å; F428-W441 AromaticContact CZ-CE2 3.95Å; F428-W441 HydrophobicContact CZ-CG 4.08Å; F428-W441 AromaticContact CZ-NE1 3.21Å
429S97.8Very high97.3Very high13 Ų1358.6 Ų58.69%0.09133%0.332CS..  trans-53146.9167.294.70000110.4E426 E431 K432 V433E426-S429 PolarHBondContact O-N 2.66Å; S429-E431 WeakPolarHBondContact CB-OE2 3.43Å; S429-E431 PolarHBondContact O-N 3.13Å; S429-E431 VanDerWaalsContact O-N 3.1Å; S429-E431 PolarHBondContact OG-OE2 2.8Å; S429-K432 PolarHBondContact O-N 3.06Å; S429-K432 VanDerWaalsContact O-N 3.08Å; S429-K432 PolarHBondContact OG-N 3.47Å; S429-V433 WeakPolarHBondContact O-CG2 3.38Å; S429-V433 PolarHBondContact O-N 3.42Å
430P96.6Very high97.3Very high74 Ų7454.5 Ų54.548%0.48131%0.309SS..Hα-helixtrans-50.9-38-178.6-28.536.2000113.5T360 A434T360-P430 HydrophobicContact CG2-CG 4.44Å; P430-A434 VanDerWaalsContact O-CB 3.32Å; P430-A434 WeakPolarHBondContact O-CB 3.26Å; P430-A434 PolarHBondContact O-N 3.12Å
431E97.1Very high97.4Very high132 Ų13256.1 Ų56.162%0.61731%0.312SS*.Hα-helixtrans-67.9-47180-53.470.8-150.700111.4S429 V433 A434 A435S429-E431 WeakPolarHBondContact CB-OE2 3.43Å; S429-E431 PolarHBondContact O-N 3.13Å; S429-E431 VanDerWaalsContact O-N 3.1Å; S429-E431 PolarHBondContact OG-OE2 2.8Å; E431-V433 VanDerWaalsContact C-N 3.34Å; E431-A434 PolarHBondContact O-N 3.31Å; E431-A435 WeakPolarHBondContact O-CB 3.33Å; E431-A435 PolarHBondContact O-N 3.31Å
432K97.3Very high97.4Very high98 Ų9851.1 Ų51.143%0.42629%0.289SS..Hα-helixtrans-67.5-35.9178.4-69.8-170.3-164.8156.90112E426 R427 S429 R436E426-K432 VanDerWaalsContact O-CD 3.27Å; E426-K432 WeakPolarHBondContact O-CD 3.21Å; E426-K432 WeakPolarHBondContact O-CE 3.08Å; E426-K432 PolarHBondContact O-NZ 3.33Å; R427-K432 WeakPolarHBondContact O-CB 3.39Å; S429-K432 PolarHBondContact O-N 3.06Å; S429-K432 VanDerWaalsContact O-N 3.08Å; S429-K432 PolarHBondContact OG-N 3.47Å; K432-R436 WeakPolarHBondContact O-CB 3.32Å; K432-R436 PolarHBondContact O-N 3.48Å
433V97.2Very high97.4Very high70 Ų7048.5 Ų48.542%0.42427%0.274SS..Hα-helixtrans-66.3-42.3174.5174.30000110.8F428 S429 E431 A435 R436F428-V433 HydrophobicContact CB-CG2 4.24Å; F428-V433 HydrophobicContact CD1-CG2 3.98Å; S429-V433 WeakPolarHBondContact O-CG2 3.38Å; S429-V433 PolarHBondContact O-N 3.42Å; E431-V433 VanDerWaalsContact C-N 3.34Å; V433-A435 VanDerWaalsContact C-N 3.32Å; V433-A435 PolarHBondContact O-N 3.48Å; V433-R436 PolarHBondContact O-N 3.03Å
434A96.8Very high97.4Very high87 Ų8749.8 Ų49.872%0.71928%0.279SS*.Hα-helixtrans-66.5-32.3178.700000113.1P430 E431P430-A434 VanDerWaalsContact O-CB 3.32Å; P430-A434 WeakPolarHBondContact O-CB 3.26Å; P430-A434 PolarHBondContact O-N 3.12Å; E431-A434 PolarHBondContact O-N 3.31Å
435A96.5Very high97.3Very high91 Ų9148.2 Ų48.275%0.75227%0.274SS*.Hα-helixtrans-80-16.417700000113.8E431 V433E431-A435 WeakPolarHBondContact O-CB 3.33Å; E431-A435 PolarHBondContact O-N 3.31Å; V433-A435 VanDerWaalsContact C-N 3.32Å; V433-A435 PolarHBondContact O-N 3.48Å
436R95.9Very high97.3Very high42 Ų4249.6 Ų49.616%0.15828%0.281CS..SBendtrans-85.3141.1-176-169.1-174.4-70.2127.110.6111.4R427 K432 V433 E440R427-R436 PolarHBondContact O-NH2 3.23Å; K432-R436 WeakPolarHBondContact O-CB 3.32Å; K432-R436 PolarHBondContact O-N 3.48Å; V433-R436 PolarHBondContact O-N 3.03Å; R436-E440 HydrophobicContact CG-CB 3.91Å; R436-E440 WeakPolarHBondContact CG-OE2 3.18Å
437E96.7Very high97.2Very high79 Ų7947.3 Ų47.337%0.36927%0.274SS..  trans-68.3133166.8-73.8-68.3176.300111K90 V439 E440K90-E437 VanDerWaalsContact NZ-CD 3.25Å; K90-E437 IonicContact NZ-OE1 3.11Å; K90-E437 PolarHBondContact NZ-OE1 3.35Å; K90-E437 VanDerWaalsContact NZ-OE1 3.16Å; K90-E437 IonicContact NZ-OE2 3.21Å; K90-E437 PolarHBondContact NZ-OE2 2.84Å; E437-V439 HydrophobicContact CB-CG2 4.44Å; E437-V439 PolarHBondContact O-N 3.42Å; E437-E440 HydrophobicContact CB-CG 4.02Å; E437-E440 WeakPolarHBondContact O-CB 3.38Å; E437-E440 PolarHBondContact O-N 3.22Å
438S95.3Very high97.2Very high59 Ų5949.4 Ų49.441%0.41329%0.291SS..G310 helixtrans-57.6-31.4-17362.70000113.2E440 W441 D446S438-E440 VanDerWaalsContact C-N 3.26Å; S438-E440 PolarHBondContact O-N 3.14Å; S438-W441 CarbonylContact O-C 3.33Å; S438-W441 PolarHBondContact O-N 3.48Å; S438-W441 VanDerWaalsContact O-O 3.04Å; S438-D446 WeakPolarHBondContact CB-OD2 3.25Å; S438-D446 PolarHBondContact OG-OD2 3.29Å
439V97.1Very high97.2Very high2 Ų249 Ų491%0.01229%0.289CS..G310 helixtrans-76.4-5.9179.7-64.70000115.2K90 L93 I94 E437 W441 L442 D446K90-V439 HydrophobicContact CB-CG1 3.99Å; K90-V439 HydrophobicContact CB-CG2 3.9Å; K90-V439 HydrophobicContact CG-CG1 4.34Å; L93-V439 HydrophobicContact CD1-CG1 4.19Å; I94-V439 HydrophobicContact CD1-CG1 4.16Å; E437-V439 HydrophobicContact CB-CG2 4.44Å; E437-V439 PolarHBondContact O-N 3.42Å; V439-W441 VanDerWaalsContact C-N 3.27Å; V439-L442 HydrophobicContact CB-CD2 4.36Å; V439-L442 HydrophobicContact CG1-CD2 4.44Å; V439-L442 VanDerWaalsContact O-CD1 3.24Å; V439-L442 WeakPolarHBondContact O-CD1 3.5Å; V439-L442 VanDerWaalsContact O-CG 3.25Å; V439-L442 WeakPolarHBondContact O-CG 3.36Å; V439-D446 HydrophobicContact CG1-CB 4.45Å
440E97.7Very high97.1Very high36 Ų3650.3 Ų50.317%0.16830%0.295CS..G310 helixtrans-81.4-13.3171.7-62173.1-177.100111.3T86 H411 L416 Y417 R436 E437 S438T86-E440 HydrophobicContact CG2-CG 4.39Å; H411-E440 PolarHBondContact CD2-O 3.41Å; L416-E440 HydrophobicContact CD1-CB 4.24Å; L416-E440 HydrophobicContact CD1-CG 4.11Å; L416-E440 HydrophobicContact CD2-CG 4.09Å; Y417-E440 WeakPolarHBondContact CE2-O 3.47Å; Y417-E440 PolarHBondContact OH-O 3.37Å; R436-E440 HydrophobicContact CG-CB 3.91Å; R436-E440 WeakPolarHBondContact CG-OE2 3.18Å; E437-E440 HydrophobicContact CB-CG 4.02Å; E437-E440 WeakPolarHBondContact O-CB 3.38Å; E437-E440 PolarHBondContact O-N 3.22Å; S438-E440 VanDerWaalsContact C-N 3.26Å; S438-E440 PolarHBondContact O-N 3.14Å
441W98.3Very high97.2Very high52 Ų5249.2 Ų49.220%0.19729%0.289CS..  trans-13296.4174.3-171.374.4000111.3S367 L370 Y417 F428 S438 V439 P443 F444S367-W441 PolarHBondContact O-NE1 3.41Å; L370-W441 HydrophobicContact CB-CZ2 4.24Å; L370-W441 HydrophobicContact CD1-CZ2 4.3Å; Y417-W441 WeakPolarHBondContact OH-CB 3.4Å; F428-W441 AromaticContact CE1-CD1 3.48Å; F428-W441 VanDerWaalsContact CE1-CD1 3.48Å; F428-W441 AromaticContact CE1-CD2 3.87Å; F428-W441 HydrophobicContact CE1-CD2 3.87Å; F428-W441 AromaticContact CE1-CE2 3.56Å; F428-W441 AromaticContact CE1-CG 3.77Å; F428-W441 HydrophobicContact CE1-CG 3.77Å; F428-W441 HydrophobicContact CE1-CZ2 4.24Å; F428-W441 AromaticContact CE1-NE1 3.32Å; F428-W441 VanDerWaalsContact CE1-NE1 3.32Å; F428-W441 AromaticContact CZ-CD1 3.34Å; F428-W441 HydrophobicContact CZ-CD2 4.45Å; F428-W441 AromaticContact CZ-CE2 3.95Å; F428-W441 HydrophobicContact CZ-CG 4.08Å; F428-W441 AromaticContact CZ-NE1 3.21Å; S438-W441 CarbonylContact O-C 3.33Å; S438-W441 PolarHBondContact O-N 3.48Å; S438-W441 VanDerWaalsContact O-O 3.04Å; V439-W441 VanDerWaalsContact C-N 3.27Å; W441-P443 HydrophobicContact CD2-CG 3.66Å; W441-P443 HydrophobicContact CE3-CG 3.91Å; W441-P443 HydrophobicContact CG-CG 4.39Å; W441-P443 HydrophobicContact CH2-CG 3.59Å; W441-P443 HydrophobicContact CZ2-CG 3.3Å; W441-P443 HydrophobicContact CZ3-CG 3.87Å; W441-P443 WeakPolarHBondContact O-CD 3.16Å; W441-F444 HydrophobicContact CH2-CD2 4.32Å; W441-F444 HydrophobicContact CH2-CE2 4.24Å
442L98.3Very high97.1Very high2 Ų244.1 Ų44.11%0.0127%0.265CS..  trans-112.531.7-170.2-66.9174.3000116.3L93 L379 I405 A407 Y410 H411 V439 F444 G445 D446L93-L442 HydrophobicContact CD1-CD1 4.28Å; L93-L442 HydrophobicContact CD1-CD2 3.9Å; L379-L442 HydrophobicContact CD1-CB 4.31Å; L379-L442 HydrophobicContact CD1-CD1 4.08Å; L379-L442 HydrophobicContact CD1-CD2 4.18Å; L379-L442 HydrophobicContact CD1-CG 4.45Å; I405-L442 HydrophobicContact CG2-CD1 3.89Å; A407-L442 HydrophobicContact CB-CB 3.85Å; A407-L442 HydrophobicContact CB-CD1 4.45Å; Y410-L442 HydrophobicContact CD2-CD1 3.98Å; Y410-L442 HydrophobicContact CE2-CD1 4.28Å; H411-L442 PolarHBondContact NE2-N 3.14Å; V439-L442 HydrophobicContact CB-CD2 4.36Å; V439-L442 HydrophobicContact CG1-CD2 4.44Å; V439-L442 VanDerWaalsContact O-CD1 3.24Å; V439-L442 WeakPolarHBondContact O-CD1 3.5Å; V439-L442 VanDerWaalsContact O-CG 3.25Å; V439-L442 WeakPolarHBondContact O-CG 3.36Å; L442-F444 PolarHBondContact O-N 2.94Å; L442-F444 VanDerWaalsContact O-N 3.14Å; L442-G445 PolarHBondContact O-N 3.42Å; L442-D446 HydrophobicContact CD2-CB 3.75Å
443P97.1Very high97Very high25 Ų2540.3 Ų40.316%0.16225%0.253CS..THydrogen-bonded Turntrans-66.7-20.5-178.128.4-33.7000113.5L370 W441L370-P443 HydrophobicContact CB-CB 3.77Å; L370-P443 HydrophobicContact CB-CG 4.03Å; L370-P443 HydrophobicContact CD1-CB 4.38Å; L370-P443 HydrophobicContact CD1-CG 4.4Å; L370-P443 HydrophobicContact CD2-CB 4.31Å; L370-P443 HydrophobicContact CG-CB 4.39Å; W441-P443 HydrophobicContact CD2-CG 3.66Å; W441-P443 HydrophobicContact CE3-CG 3.91Å; W441-P443 HydrophobicContact CG-CG 4.39Å; W441-P443 HydrophobicContact CH2-CG 3.59Å; W441-P443 HydrophobicContact CZ2-CG 3.3Å; W441-P443 HydrophobicContact CZ3-CG 3.87Å; W441-P443 WeakPolarHBondContact O-CD 3.16Å
444F97.7Very high96.9Very high38 Ų3839.6 Ų39.617%0.16725%0.246CC..THydrogen-bonded Turntrans-109.97.1173.4-62.7-73.1000112.7L370 W441 L442 C451 M454 Q458L370-F444 HydrophobicContact CD1-CE2 3.56Å; L370-F444 HydrophobicContact CD1-CZ 3.7Å; W441-F444 HydrophobicContact CH2-CD2 4.32Å; W441-F444 HydrophobicContact CH2-CE2 4.24Å; L442-F444 PolarHBondContact O-N 2.94Å; L442-F444 VanDerWaalsContact O-N 3.14Å; F444-C451 HydrophobicContact CB-CB 3.85Å; F444-C451 HydrophobicContact CD1-CB 3.88Å; F444-C451 HydrophobicContact CG-CB 4.35Å; F444-C451 WeakPolarHBondContact O-CB 3.15Å; F444-C451 PolarHBondContact O-N 2.87Å; F444-M454 HydrophobicContact CB-CB 4.43Å; F444-M454 HydrophobicContact CB-CG 4.17Å; F444-M454 HydrophobicContact CB-SD 3.89Å; F444-M454 HydrophobicContact CD1-CB 3.95Å; F444-M454 HydrophobicContact CD1-CG 3.84Å; F444-M454 HydrophobicContact CD2-CG 3.76Å; F444-M454 HydrophobicContact CD2-SD 3.86Å; F444-M454 HydrophobicContact CE1-CB 4.41Å; F444-M454 HydrophobicContact CE1-CG 4.16Å; F444-M454 HydrophobicContact CE2-CG 4.08Å; F444-M454 HydrophobicContact CG-CB 4.1Å; F444-M454 HydrophobicContact CG-CG 3.63Å; F444-M454 HydrophobicContact CG-SD 3.88Å; F444-M454 HydrophobicContact CZ-CG 4.27Å; F444-Q458 HydrophobicContact CE2-CG 4.38Å; F444-Q458 HydrophobicContact CZ-CG 4.17Å
445G97.7Very high96.8Very high14 Ų1441.2 Ų41.214%0.14423%0.234CC..  trans59.6-173.2-16400000113.3L442L442-G445 PolarHBondContact O-N 3.42Å
446D97.6Very high96.7Very high32 Ų3237.4 Ų37.417%0.17120%0.2CC..  trans-140.6169.1-178.5-152.2-12.6000111.9L93 S438 V439 L442L93-D446 HydrophobicContact CD1-CB 4.22Å; S438-D446 WeakPolarHBondContact CB-OD2 3.25Å; S438-D446 PolarHBondContact OG-OD2 3.29Å; V439-D446 HydrophobicContact CG1-CB 4.45Å; L442-D446 HydrophobicContact CD2-CB 3.75Å
447G97.3Very high96.6Very high14 Ų1435.9 Ų35.914%0.14420%0.198CC..SBendtrans72.1-168-179.100000114.3L93 R449 N450L93-G447 WeakPolarHBondContact O-CA 3.08Å; G447-R449 PolarHBondContact O-N 3.32Å; G447-N450 WeakPolarHBondContact O-CB 3.43Å; G447-N450 PolarHBondContact O-N 3.31Å; G447-N450 VanDerWaalsContact O-N 3.08Å
448P97.4Very high96.5Very high65 Ų6533.8 Ų33.842%0.42219%0.188SC..THydrogen-bonded Turntrans-60.2-17.7-173.2-26.736.1000115.5F97F97-P448 HydrophobicContact CB-CG 4.42Å; F97-P448 HydrophobicContact CD1-CB 3.92Å; F97-P448 HydrophobicContact CD1-CG 3.65Å; F97-P448 HydrophobicContact CD2-CB 4.48Å; F97-P448 HydrophobicContact CD2-CG 4.26Å; F97-P448 HydrophobicContact CE1-CB 3.69Å; F97-P448 HydrophobicContact CE1-CG 3.98Å; F97-P448 HydrophobicContact CE2-CB 4.28Å; F97-P448 HydrophobicContact CG-CB 4.32Å; F97-P448 HydrophobicContact CG-CG 3.81Å; F97-P448 HydrophobicContact CZ-CB 3.9Å; F97-P448 HydrophobicContact CZ-CG 4.43Å
449R97Very high96.5Very high3 Ų331.3 Ų31.31%0.01117%0.17CC..THydrogen-bonded Turntrans-111.824-179.1-161159.4179.2167.1-5.7113.3F97 A101 D102 R103 L121 D122 W126 G447F97-R449 HydrophobicContact CE2-CB 3.65Å; F97-R449 HydrophobicContact CZ-CB 3.91Å; A101-R449 WeakPolarHBondContact O-CD 3.26Å; A101-R449 PolarHBondContact O-NH1 2.64Å; D102-R449 IonicContact OD1-NH1 3.28Å; R103-R449 PolarHBondContact NH2-O 3.44Å; L121-R449 PolarHBondContact O-NH1 2.85Å; L121-R449 PolarHBondContact O-NH2 3.16Å; D122-R449 IonicContact OD1-CZ 3.25Å; D122-R449 IonicContact OD1-NH1 3.77Å; D122-R449 PolarHBondContact OD1-NH1 3.07Å; D122-R449 IonicContact OD1-NH2 2.75Å; D122-R449 PolarHBondContact OD1-NH2 3.21Å; W126-R449 VanDerWaalsContact CE2-CD 3.45Å; W126-R449 HydrophobicContact CH2-CB 4.09Å; W126-R449 HydrophobicContact CH2-CG 4.32Å; W126-R449 HydrophobicContact CZ2-CB 3.57Å; W126-R449 HydrophobicContact CZ2-CG 3.45Å; W126-R449 VanDerWaalsContact CZ2-CG 3.45Å; G447-R449 PolarHBondContact O-N 3.32Å
450N97.4Very high96.3Very high41 Ų4131.3 Ų31.322%0.21917%0.169CC..SBendtrans-65.3175.1169.475.5-11.1000112.6R130 G447 I452R130-N450 PolarHBondContact NH1-O 3.12Å; R130-N450 PolarHBondContact NH2-O 3.34Å; R130-N450 PolarHBondContact NH2-OD1 3.05Å; G447-N450 WeakPolarHBondContact O-CB 3.43Å; G447-N450 PolarHBondContact O-N 3.31Å; G447-N450 VanDerWaalsContact O-N 3.08Å; N450-I452 PolarHBondContact O-N 2.83Å
451C97.6Very high96.3Very high52 Ų5229.7 Ų29.735%0.35116%0.163SC..  trans-60.7117.8177.8-174.60000111.5F444 G453 M454F444-C451 HydrophobicContact CB-CB 3.85Å; F444-C451 HydrophobicContact CD1-CB 3.88Å; F444-C451 HydrophobicContact CG-CB 4.35Å; F444-C451 WeakPolarHBondContact O-CB 3.15Å; F444-C451 PolarHBondContact O-N 2.87Å; C451-G453 VanDerWaalsContact C-N 3.27Å; C451-G453 PolarHBondContact O-N 3.31Å; C451-M454 HydrophobicContact CB-CB 4.36Å
452I96Very high96.2Very high25 Ų2529.6 Ų29.613%0.12816%0.162CC..THydrogen-bonded Turntrans-67-32.2177-158.9175.7000111.9L118 L133 F137 F307 N450L118-I452 HydrophobicContact CD2-CB 4.34Å; L118-I452 HydrophobicContact CD2-CD1 3.86Å; L118-I452 HydrophobicContact CD2-CG2 4.02Å; L133-I452 HydrophobicContact CB-CD1 3.72Å; F137-I452 WeakPolarHBondContact CB-O 3.25Å; F137-I452 HydrophobicContact CD2-CD1 3.86Å; F137-I452 HydrophobicContact CD2-CG1 3.65Å; F137-I452 HydrophobicContact CD2-CG2 4.41Å; F137-I452 HydrophobicContact CE2-CD1 4.13Å; F137-I452 HydrophobicContact CE2-CG1 4.2Å; F137-I452 HydrophobicContact CE2-CG2 4.22Å; F137-I452 HydrophobicContact CG-CG1 4.3Å; F137-I452 WeakPolarHBondContact CG-O 3.31Å; F307-I452 HydrophobicContact CE1-CG2 3.64Å; F307-I452 HydrophobicContact CZ-CG2 3.88Å; N450-I452 PolarHBondContact O-N 2.83Å
453G94.6Very high96.2Very high17 Ų1729.5 Ų29.518%0.17516%0.161CC..THydrogen-bonded Turntrans-897.2-175.500000114.5C451 R455 F456 G457C451-G453 VanDerWaalsContact C-N 3.27Å; C451-G453 PolarHBondContact O-N 3.31Å; G453-R455 VanDerWaalsContact C-N 3.32Å; G453-R455 PolarHBondContact O-N 3.21Å; G453-F456 PolarHBondContact O-N 3.29Å; G453-G457 PolarHBondContact O-N 2.86Å
454M95.7Very high96.2Very high55 Ų5528.3 Ų28.327%0.27115%0.154SC..Hα-helixtrans-50-48.9-174177.5177.370.400112.7F444 C451 F456 G457 Q458F444-M454 HydrophobicContact CB-CB 4.43Å; F444-M454 HydrophobicContact CB-CG 4.17Å; F444-M454 HydrophobicContact CB-SD 3.89Å; F444-M454 HydrophobicContact CD1-CB 3.95Å; F444-M454 HydrophobicContact CD1-CG 3.84Å; F444-M454 HydrophobicContact CD2-CG 3.76Å; F444-M454 HydrophobicContact CD2-SD 3.86Å; F444-M454 HydrophobicContact CE1-CB 4.41Å; F444-M454 HydrophobicContact CE1-CG 4.16Å; F444-M454 HydrophobicContact CE2-CG 4.08Å; F444-M454 HydrophobicContact CG-CB 4.1Å; F444-M454 HydrophobicContact CG-CG 3.63Å; F444-M454 HydrophobicContact CG-SD 3.88Å; F444-M454 HydrophobicContact CZ-CG 4.27Å; C451-M454 HydrophobicContact CB-CB 4.36Å; M454-F456 PolarHBondContact O-N 2.96Å; M454-G457 PolarHBondContact O-N 3.14Å; M454-Q458 WeakPolarHBondContact O-CB 3.39Å; M454-Q458 WeakPolarHBondContact O-CG 3.33Å; M454-Q458 PolarHBondContact O-N 3.38Å
455R94Very high96.2Very high122 Ų12226.5 Ų26.546%0.4615%0.146SC..Hα-helixtrans-64.4-40.5-179.2-65.3-176.2-177.8126.3-1.7112.7F137 M142 G453 M459F137-R455 PolarHBondContact O-NH1 3.43Å; M142-R455 HydrophobicContact CG-CB 4.09Å; M142-R455 HydrophobicContact SD-CB 4.25Å; G453-R455 VanDerWaalsContact C-N 3.32Å; G453-R455 PolarHBondContact O-N 3.21Å; R455-M459 WeakPolarHBondContact O-CB 3.46Å; R455-M459 PolarHBondContact O-N 2.76Å
456F93.5Very high96.2Very high11 Ų1125.9 Ų25.95%0.04814%0.139CC..Hα-helixtrans-67.4-46.1178-177.7-95.8000111F137 M142 M145 I187 C190 G453 M454 Q458 M459 Q460F137-F456 HydrophobicContact CD1-CB 4.27Å; F137-F456 HydrophobicContact CE1-CB 4.32Å; M142-F456 HydrophobicContact SD-CB 3.88Å; M142-F456 HydrophobicContact SD-CD2 4.22Å; M145-F456 HydrophobicContact CE-CD2 4.14Å; M145-F456 HydrophobicContact CE-CE2 4.48Å; I187-F456 HydrophobicContact CD1-CE1 3.88Å; I187-F456 HydrophobicContact CD1-CZ 4.29Å; C190-F456 HydrophobicContact CB-CE2 4.08Å; C190-F456 HydrophobicContact CB-CZ 4.18Å; G453-F456 PolarHBondContact O-N 3.29Å; M454-F456 PolarHBondContact O-N 2.96Å; F456-Q458 PolarHBondContact O-N 3.2Å; F456-M459 HydrophobicContact CD2-CE 3.71Å; F456-M459 HydrophobicContact CE2-CE 4.05Å; F456-M459 WeakPolarHBondContact O-CB 3.46Å; F456-M459 PolarHBondContact O-N 3.02Å; F456-Q460 PolarHBondContact O-N 2.68Å
457G94.6Very high96.1Very high10 Ų1024.6 Ų24.610%0.10313%0.133CC..Hα-helixtrans-57.9-46.417600000112.7G453 M454 Q460 A461G453-G457 PolarHBondContact O-N 2.86Å; M454-G457 PolarHBondContact O-N 3.14Å; G457-Q460 VanDerWaalsContact O-CG 3.23Å; G457-Q460 WeakPolarHBondContact O-CG 3.25Å; G457-A461 WeakPolarHBondContact O-CB 3.23Å; G457-A461 PolarHBondContact O-N 3.34Å
458Q95.4Very high96.1Very high35 Ų3524.3 Ų24.316%0.16413%0.127CC..Hα-helixtrans-63.2-42.2175.2-74.2177.7-27.800112.1F444 M454 F456 A461 R462F444-Q458 HydrophobicContact CE2-CG 4.38Å; F444-Q458 HydrophobicContact CZ-CG 4.17Å; M454-Q458 WeakPolarHBondContact O-CB 3.39Å; M454-Q458 WeakPolarHBondContact O-CG 3.33Å; M454-Q458 PolarHBondContact O-N 3.38Å; F456-Q458 PolarHBondContact O-N 3.2Å; Q458-A461 PolarHBondContact O-N 3.47Å; Q458-R462 WeakPolarHBondContact O-CB 3.3Å; Q458-R462 WeakPolarHBondContact O-CD 3.37Å; Q458-R462 WeakPolarHBondContact O-CG 3.41Å; Q458-R462 PolarHBondContact O-N 3.01Å
459M94.6Very high96.1Very high7 Ų721.2 Ų21.23%0.03411%0.107CC..Hα-helixtrans-60.6-50.1178.2-179.4175.862.900111.6M142 F146 V149 Y353 R455 F456 A461 R462 I463M142-M459 HydrophobicContact CB-CE 4.49Å; M142-M459 HydrophobicContact CB-SD 4.22Å; M142-M459 HydrophobicContact SD-CE 4.09Å; F146-M459 HydrophobicContact CD2-CG 4.44Å; F146-M459 HydrophobicContact CD2-SD 3.93Å; V149-M459 HydrophobicContact CG2-CE 3.9Å; Y353-M459 HydrophobicContact CE2-SD 4.46Å; R455-M459 WeakPolarHBondContact O-CB 3.46Å; R455-M459 PolarHBondContact O-N 2.76Å; F456-M459 HydrophobicContact CD2-CE 3.71Å; F456-M459 HydrophobicContact CE2-CE 4.05Å; F456-M459 WeakPolarHBondContact O-CB 3.46Å; F456-M459 PolarHBondContact O-N 3.02Å; M459-A461 PolarHBondContact O-N 2.73Å; M459-R462 PolarHBondContact O-N 3.35Å; M459-I463 HydrophobicContact CG-CD1 3.73Å; M459-I463 WeakPolarHBondContact O-CD1 3.34Å; M459-I463 WeakPolarHBondContact O-CG1 3.26Å; M459-I463 PolarHBondContact O-N 3.47Å
460Q93.5Very high96Very high1 Ų121.8 Ų21.81%0.00511%0.112CC..Hα-helixtrans-65.3-38.5179.266177.9-2600112.4G311 S315 F456 G457 G464G311-Q460 PolarHBondContact O-NE2 2.64Å; S315-Q460 VanDerWaalsContact CB-CD 3.47Å; S315-Q460 PolarHBondContact OG-NE2 3.35Å; F456-Q460 PolarHBondContact O-N 2.68Å; G457-Q460 VanDerWaalsContact O-CG 3.23Å; G457-Q460 WeakPolarHBondContact O-CG 3.25Å; Q460-G464 PolarHBondContact O-N 2.67Å
461A96.6Very high95.9Very high3 Ų324.4 Ų24.43%0.02512%0.119CC..Hα-helixtrans-64.6-46.2177.900000111.9M319 I366 G457 Q458 M459 L465M319-A461 HydrophobicContact CG-CB 4.09Å; I366-A461 HydrophobicContact CD1-CB 4.36Å; G457-A461 WeakPolarHBondContact O-CB 3.23Å; G457-A461 PolarHBondContact O-N 3.34Å; Q458-A461 PolarHBondContact O-N 3.47Å; M459-A461 PolarHBondContact O-N 2.73Å; A461-L465 WeakPolarHBondContact O-CB 3.27Å; A461-L465 WeakPolarHBondContact O-CD1 3.37Å; A461-L465 VanDerWaalsContact O-CG 3.26Å; A461-L465 WeakPolarHBondContact O-CG 3.41Å; A461-L465 PolarHBondContact O-N 2.77Å
462R97.4Very high95.9Very high49 Ų4922 Ų2219%0.18510%0.102CC..Hα-helixtrans-59.7-48.7177.1-70.5163.3-173.6161.9-4.9111.5I356 L362 N363 I366 Q458 M459 A466I356-R462 HydrophobicContact CD1-CB 4.4Å; I356-R462 HydrophobicContact CG2-CB 3.69Å; I356-R462 VanDerWaalsContact CG2-CD 3.49Å; I356-R462 HydrophobicContact CG2-CG 4.2Å; L362-R462 HydrophobicContact CD2-CB 3.93Å; L362-R462 HydrophobicContact CD2-CG 4.17Å; L362-R462 HydrophobicContact CG-CG 4.46Å; N363-R462 PolarHBondContact OD1-NE 2.98Å; N363-R462 PolarHBondContact OD1-NH2 3.01Å; I366-R462 HydrophobicContact CD1-CB 4.36Å; I366-R462 HydrophobicContact CD1-CG 3.61Å; Q458-R462 WeakPolarHBondContact O-CB 3.3Å; Q458-R462 WeakPolarHBondContact O-CD 3.37Å; Q458-R462 WeakPolarHBondContact O-CG 3.41Å; Q458-R462 PolarHBondContact O-N 3.01Å; M459-R462 PolarHBondContact O-N 3.35Å; R462-A466 WeakPolarHBondContact O-CB 3.48Å; R462-A466 PolarHBondContact O-N 2.8Å
463I96.8Very high95.9Very high0 Ų024.2 Ų24.20%011%0.109CC..Hα-helixtrans-65.4-47.6-178.3-68.6163000110.4F146 V149 I150 I356 M459 L465 A466 Q467F146-I463 HydrophobicContact CD2-CD1 4.09Å; F146-I463 HydrophobicContact CE2-CD1 3.61Å; F146-I463 HydrophobicContact CE2-CG1 4.34Å; F146-I463 HydrophobicContact CZ-CD1 4.32Å; V149-I463 HydrophobicContact CB-CD1 4.39Å; V149-I463 HydrophobicContact CG1-CD1 3.35Å; I150-I463 HydrophobicContact CD1-CD1 4.32Å; I150-I463 HydrophobicContact CD1-CG2 4.18Å; I356-I463 HydrophobicContact CD1-CG1 3.71Å; I356-I463 HydrophobicContact CG1-CG1 3.87Å; M459-I463 HydrophobicContact CG-CD1 3.73Å; M459-I463 WeakPolarHBondContact O-CD1 3.34Å; M459-I463 WeakPolarHBondContact O-CG1 3.26Å; M459-I463 PolarHBondContact O-N 3.47Å; I463-L465 PolarHBondContact O-N 3.35Å; I463-A466 PolarHBondContact O-N 3.41Å; I463-Q467 HydrophobicContact CG2-CG 4.23Å; I463-Q467 WeakPolarHBondContact O-CB 3.35Å; I463-Q467 WeakPolarHBondContact O-CG 3.42Å; I463-Q467 PolarHBondContact O-N 2.94Å
464G97Very high96.1Very high0 Ų023.5 Ų23.50%010%0.101CC..Hα-helixtrans-58.5-47.3178.800000112.4Q460 I468Q460-G464 PolarHBondContact O-N 2.67Å; G464-I468 VanDerWaalsContact O-CG1 3.31Å; G464-I468 WeakPolarHBondContact O-CG1 3.4Å; G464-I468 PolarHBondContact O-N 3.34Å
465L98.3Very high96.2Very high0 Ų022 Ų220%010%0.096CC..Hα-helixtrans-68-44178.5-69.4166.8000112.2M319 C322 L323 L362 I366 A461 I463 Q467 I468 I469M319-L465 HydrophobicContact CB-CD2 4.32Å; M319-L465 HydrophobicContact CB-CG 4.49Å; M319-L465 HydrophobicContact CG-CD1 4.36Å; M319-L465 HydrophobicContact CG-CD2 4.4Å; M319-L465 HydrophobicContact CG-CG 4.04Å; C322-L465 HydrophobicContact CB-CD1 4.07Å; C322-L465 HydrophobicContact CB-CD2 4Å; L323-L465 HydrophobicContact CD1-CD2 4.46Å; L323-L465 HydrophobicContact CD2-CD2 3.85Å; L323-L465 HydrophobicContact CG-CD2 3.8Å; L362-L465 HydrophobicContact CD1-CB 4Å; L362-L465 HydrophobicContact CD1-CD1 4.38Å; I366-L465 HydrophobicContact CD1-CD1 3.85Å; I366-L465 HydrophobicContact CG1-CD1 3.57Å; A461-L465 WeakPolarHBondContact O-CB 3.27Å; A461-L465 WeakPolarHBondContact O-CD1 3.37Å; A461-L465 VanDerWaalsContact O-CG 3.26Å; A461-L465 WeakPolarHBondContact O-CG 3.41Å; A461-L465 PolarHBondContact O-N 2.77Å; I463-L465 PolarHBondContact O-N 3.35Å; L465-Q467 VanDerWaalsContact C-N 3.3Å; L465-Q467 PolarHBondContact O-N 2.67Å; L465-I468 PolarHBondContact O-N 3.16Å; L465-I469 WeakPolarHBondContact O-CB 3.36Å; L465-I469 WeakPolarHBondContact O-CG1 3.5Å; L465-I469 PolarHBondContact O-N 3.23Å
466A97.5Very high96.3Very high1 Ų119.3 Ų19.31%0.0089%0.091CC..Hα-helixtrans-59.7-43177.600000111.5I340 L351 I356 M359 L362 R462 I463 I468 S470I340-A466 HydrophobicContact CD1-CB 4.45Å; I340-A466 HydrophobicContact CG2-CB 4.37Å; L351-A466 HydrophobicContact CD2-CB 4.24Å; I356-A466 HydrophobicContact CD1-CB 4.38Å; M359-A466 HydrophobicContact CE-CB 4.43Å; M359-A466 HydrophobicContact SD-CB 4.08Å; L362-A466 HydrophobicContact CD2-CB 4.21Å; R462-A466 WeakPolarHBondContact O-CB 3.48Å; R462-A466 PolarHBondContact O-N 2.8Å; I463-A466 PolarHBondContact O-N 3.41Å; A466-I468 VanDerWaalsContact C-N 3.34Å; A466-I468 PolarHBondContact O-N 3.14Å; A466-S470 VanDerWaalsContact O-CB 3.23Å; A466-S470 WeakPolarHBondContact O-CB 3.27Å; A466-S470 PolarHBondContact O-N 3.33Å; A466-S470 VanDerWaalsContact O-N 3.09Å; A466-S470 PolarHBondContact O-OG 2.9Å
467Q95.8Very high96.5Very high6 Ų619.5 Ų19.53%0.0289%0.093CC..Hα-helixtrans-61.4-39.7177.8-73.4-74.428.900113S153 V157 L351 I463 L465 R471S153-Q467 PolarHBondContact OG-NE2 2.78Å; V157-Q467 HydrophobicContact CG2-CB 3.7Å; V157-Q467 HydrophobicContact CG2-CG 4.12Å; L351-Q467 HydrophobicContact CD1-CG 3.68Å; I463-Q467 HydrophobicContact CG2-CG 4.23Å; I463-Q467 WeakPolarHBondContact O-CB 3.35Å; I463-Q467 WeakPolarHBondContact O-CG 3.42Å; I463-Q467 PolarHBondContact O-N 2.94Å; L465-Q467 VanDerWaalsContact C-N 3.3Å; L465-Q467 PolarHBondContact O-N 2.67Å; Q467-R471 PolarHBondContact O-NH1 3.21Å
468I97.4Very high96.5Very high7 Ų726.9 Ų26.94%0.03613%0.13CC..Hα-helixtrans-73.2-56.5178.5-64.1166.2000110F156 I160 M179 L323 G464 L465 A466 S470 R471 F472 V474F156-I468 HydrophobicContact CE1-CD1 3.86Å; F156-I468 HydrophobicContact CE1-CG1 3.77Å; F156-I468 HydrophobicContact CZ-CD1 3.8Å; F156-I468 HydrophobicContact CZ-CG1 4.06Å; I160-I468 HydrophobicContact CD1-CG1 4.08Å; M179-I468 HydrophobicContact CE-CD1 3.87Å; M179-I468 HydrophobicContact SD-CD1 4.04Å; L323-I468 HydrophobicContact CD1-CD1 3.71Å; L323-I468 HydrophobicContact CD2-CD1 4.35Å; L323-I468 HydrophobicContact CD2-CG2 4.02Å; G464-I468 VanDerWaalsContact O-CG1 3.31Å; G464-I468 WeakPolarHBondContact O-CG1 3.4Å; G464-I468 PolarHBondContact O-N 3.34Å; L465-I468 PolarHBondContact O-N 3.16Å; A466-I468 VanDerWaalsContact C-N 3.34Å; A466-I468 PolarHBondContact O-N 3.14Å; I468-S470 VanDerWaalsContact C-N 3.27Å; I468-S470 PolarHBondContact O-N 2.87Å; I468-R471 PolarHBondContact O-N 3.37Å; I468-R471 VanDerWaalsContact O-N 3.1Å; I468-F472 HydrophobicContact CG2-CB 4.39Å; I468-F472 WeakPolarHBondContact O-CA 3.42Å; I468-F472 WeakPolarHBondContact O-CB 3.45Å; I468-F472 WeakPolarHBondContact O-CD2 3.36Å; I468-F472 PolarHBondContact O-N 3.33Å; I468-V474 HydrophobicContact CG2-CG2 3.94Å
469I98Very high96.5Very high0 Ų029.3 Ų29.30%015%0.147CC..Hα-helixtrans-67.4-27.8-169.6-62.3-55.6000112.4L323 L326 Q333 L336 R337 I340 L465 R471L323-I469 HydrophobicContact CD2-CD1 3.94Å; L326-I469 HydrophobicContact CD1-CD1 3.8Å; L326-I469 HydrophobicContact CD1-CG1 4.05Å; Q333-I469 HydrophobicContact CG-CD1 4.04Å; Q333-I469 HydrophobicContact CG-CG2 4.48Å; L336-I469 HydrophobicContact CD2-CG1 4.32Å; L336-I469 HydrophobicContact CD2-CG2 4.33Å; L336-I469 HydrophobicContact CG-CG2 4.22Å; R337-I469 HydrophobicContact CB-CG2 3.84Å; R337-I469 HydrophobicContact CG-CG2 4.48Å; R337-I469 PolarHBondContact NE-O 3.05Å; I340-I469 HydrophobicContact CD1-CB 3.96Å; I340-I469 HydrophobicContact CD1-CG2 3.91Å; L465-I469 WeakPolarHBondContact O-CB 3.36Å; L465-I469 WeakPolarHBondContact O-CG1 3.5Å; L465-I469 PolarHBondContact O-N 3.23Å; I469-R471 VanDerWaalsContact C-N 3.3Å; I469-R471 PolarHBondContact O-N 3.01Å
470S95.4Very high96.6Very high16 Ų1629.8 Ų29.811%0.11215%0.151CC..THydrogen-bonded Turntrans-73.7-17.8176.5740000114.5A466 I468A466-S470 VanDerWaalsContact O-CB 3.23Å; A466-S470 WeakPolarHBondContact O-CB 3.27Å; A466-S470 PolarHBondContact O-N 3.33Å; A466-S470 VanDerWaalsContact O-N 3.09Å; A466-S470 PolarHBondContact O-OG 2.9Å; I468-S470 VanDerWaalsContact C-N 3.27Å; I468-S470 PolarHBondContact O-N 2.87Å
471R94.3Very high96.7Very high95 Ų9532.6 Ų32.636%0.35816%0.164SC..THydrogen-bonded Turntrans-125.3-16.5-172.5-71.6174.8-173.778.3-4.6114.5Q467 I468 I469 I506Q467-R471 PolarHBondContact O-NH1 3.21Å; I468-R471 PolarHBondContact O-N 3.37Å; I468-R471 VanDerWaalsContact O-N 3.1Å; I469-R471 VanDerWaalsContact C-N 3.3Å; I469-R471 PolarHBondContact O-N 3.01Å; R471-I506 VanDerWaalsContact C-CG1 3.41Å; R471-I506 VanDerWaalsContact O-CG1 3.3Å; R471-I506 WeakPolarHBondContact O-CG1 3.35Å; R471-I506 PolarHBondContact O-N 3.49Å
472F96.9Very high96.6Very high2 Ų236.8 Ų36.81%0.00919%0.185CC..EExtended strand (participates in β ladder)trans-134.7147.6-176.3-54.2-87.1000110.6I160 V164 R337 I468 V503 E504 R505I160-F472 HydrophobicContact CB-CE2 4.24Å; I160-F472 HydrophobicContact CB-CZ 4Å; I160-F472 HydrophobicContact CG2-CD1 4.16Å; I160-F472 HydrophobicContact CG2-CD2 4.24Å; I160-F472 HydrophobicContact CG2-CE1 3.64Å; I160-F472 HydrophobicContact CG2-CE2 3.75Å; I160-F472 HydrophobicContact CG2-CG 4.44Å; I160-F472 HydrophobicContact CG2-CZ 3.42Å; I160-F472 VanDerWaalsContact CG2-CZ 3.42Å; V164-F472 HydrophobicContact CB-CE1 4.3Å; V164-F472 HydrophobicContact CG2-CE1 4.41Å; R337-F472 PolarHBondContact NH2-O 2.97Å; I468-F472 HydrophobicContact CG2-CB 4.39Å; I468-F472 WeakPolarHBondContact O-CA 3.42Å; I468-F472 WeakPolarHBondContact O-CB 3.45Å; I468-F472 WeakPolarHBondContact O-CD2 3.36Å; I468-F472 PolarHBondContact O-N 3.33Å; F472-V503 HydrophobicContact CB-CG1 3.7Å; F472-V503 HydrophobicContact CD1-CG1 3.74Å; F472-V503 HydrophobicContact CG-CG1 3.86Å; F472-E504 CarbonylContact C-O 3.53Å; F472-E504 WeakPolarHBondContact CA-O 3.42Å; F472-E504 WeakPolarHBondContact CB-O 3.17Å; F472-R505 HydrophobicContact CD1-CG 4.03Å; F472-R505 HydrophobicContact CE1-CG 3.74Å
473R97.2Very high96.4Very high72 Ų7239.6 Ų39.627%0.27221%0.21SC..EExtended strand (participates in β ladder)trans-95.6135161.8-177.2176.2-70.6-91.7-1.2108.2Q330 D334 V503 E504 I506Q330-R473 VanDerWaalsContact OE1-NH1 3.07Å; D334-R473 IonicContact OD1-CZ 3.34Å; D334-R473 IonicContact OD1-NH1 3.76Å; D334-R473 PolarHBondContact OD1-NH1 2.67Å; D334-R473 IonicContact OD1-NH2 3.73Å; D334-R473 PolarHBondContact OD1-NH2 2.9Å; D334-R473 IonicContact OD2-NH1 3.15Å; D334-R473 IonicContact OD2-NH2 3.79Å; R473-V503 WeakPolarHBondContact O-CA 3.39Å; R473-E504 PolarHBondContact N-O 3.47Å; R473-E504 PolarHBondContact O-N 2.99Å; R473-I506 HydrophobicContact CB-CG2 3.96Å
474V97.9Very high96.3Very high1 Ų140.3 Ų40.31%0.00621%0.213CC..EExtended strand (participates in β ladder)trans-114130.1176.2-171.60000108.8L323 A327 Q330 Q333 I468 L501 R502 V503L323-V474 HydrophobicContact CD2-CG2 4.24Å; A327-V474 HydrophobicContact CB-CG1 4.24Å; Q330-V474 PolarHBondContact NE2-O 2.67Å; Q333-V474 PolarHBondContact NE2-O 3.23Å; I468-V474 HydrophobicContact CG2-CG2 3.94Å; V474-L501 HydrophobicContact CG1-CB 3.61Å; V474-L501 HydrophobicContact CG1-CD1 3.44Å; V474-L501 VanDerWaalsContact CG1-CD1 3.44Å; V474-L501 HydrophobicContact CG1-CG 4.09Å; V474-R502 CarbonylContact C-O 3.57Å; V474-R502 VanDerWaalsContact CA-O 3.31Å; V474-R502 WeakPolarHBondContact CA-O 3.26Å; V474-V503 HydrophobicContact CG2-CG2 4.45Å
475S97.8Very high96.2Very high24 Ų2446.4 Ų46.417%0.16824%0.24CC..EExtended strand (participates in β ladder)trans-141.2167-176.858.30000111.3R502S475-R502 PolarHBondContact N-O 3.03Å; S475-R502 PolarHBondContact O-N 2.87Å
476L97.7Very high96Very high66 Ų6649.4 Ų49.435%0.34625%0.252SS..  trans-66.5154.4176.3-56.4177.1000110.9A327 Q328 T480 I482 L501A327-L476 HydrophobicContact CB-CD2 3.99Å; Q328-L476 HydrophobicContact CG-CD1 4.27Å; Q328-L476 HydrophobicContact CG-CD2 3.81Å; Q328-L476 HydrophobicContact CG-CG 4.49Å; L476-T480 HydrophobicContact CD2-CG2 3.8Å; L476-I482 HydrophobicContact CD1-CD1 3.65Å; L476-I482 HydrophobicContact CD2-CD1 3.94Å; L476-I482 HydrophobicContact CG-CD1 4.34Å; L476-L501 HydrophobicContact CD2-CD2 4.27Å
477C95.9Very high95.7Very high14 Ų1450.8 Ų50.810%0.09526%0.261CS..  trans-136.6170.8171.770.40000110.3V172 T479 T480 R502V172-C477 HydrophobicContact CG2-CB 4Å; C477-T479 PolarHBondContact O-N 2.7Å; C477-T479 PolarHBondContact SG-OG1 2.78Å; C477-T480 PolarHBondContact N-OG1 3.15Å; C477-T480 WeakPolarHBondContact O-CB 3.22Å; C477-T480 PolarHBondContact O-N 2.86Å; C477-T480 PolarHBondContact O-OG1 2.77Å; C477-T480 PolarHBondContact SG-OG1 3.41Å; C477-R502 HydrophobicContact CB-CB 4.2Å
478D95.3Very high95.3Very high166 Ų16651.8 Ų51.889%0.88827%0.268SS*.THydrogen-bonded Turntrans-60.8-20.3-177-53.9-26.7000113.6
479T95.3Very high94.6Very high85 Ų8554 Ų5452%0.52128%0.279SS..THydrogen-bonded Turntrans-94.5-3.9177.361.40000113.9C477 E481 Y500C477-T479 PolarHBondContact O-N 2.7Å; C477-T479 PolarHBondContact SG-OG1 2.78Å; T479-E481 PolarHBondContact O-N 3.31Å; T479-Y500 VanDerWaalsContact OG1-CB 3.26Å; T479-Y500 WeakPolarHBondContact OG1-CB 3.09Å
480T96.9Very high93.8Very high17 Ų1755 Ų5510%0.10429%0.286CS..  trans-71.1120.2178.4-51.80000109.9Y324 L476 C477 I482 Y500 L501Y324-T480 HydrophobicContact CD2-CG2 4.2Å; Y324-T480 HydrophobicContact CE2-CG2 3.98Å; L476-T480 HydrophobicContact CD2-CG2 3.8Å; C477-T480 PolarHBondContact N-OG1 3.15Å; C477-T480 WeakPolarHBondContact O-CB 3.22Å; C477-T480 PolarHBondContact O-N 2.86Å; C477-T480 PolarHBondContact O-OG1 2.77Å; C477-T480 PolarHBondContact SG-OG1 3.41Å; T480-I482 HydrophobicContact CG2-CD1 4.42Å; T480-I482 HydrophobicContact CG2-CG1 4.11Å; T480-I482 PolarHBondContact O-N 2.94Å; T480-Y500 WeakPolarHBondContact CB-O 3.5Å; T480-Y500 PolarHBondContact OG1-O 2.91Å; T480-L501 HydrophobicContact CG2-CD2 3.83Å
481E96Very high93Very high60 Ų6058 Ų5828%0.2830%0.3SS..  trans-79.1121.3177.7-173.5166.3-135.200110.8T479 L484 K485T479-E481 PolarHBondContact O-N 3.31Å; E481-L484 WeakPolarHBondContact O-CD2 3.47Å; E481-K485 WeakPolarHBondContact OE1-CD 3.4Å; E481-K485 WeakPolarHBondContact OE1-CE 3.46Å; E481-K485 WeakPolarHBondContact OE1-CG 3.42Å; E481-K485 IonicContact OE1-NZ 2.68Å; E481-K485 PolarHBondContact OE1-NZ 3.01Å; E481-K485 PolarHBondContact OE2-N 2.87Å
482I94.5Very high92.7Very high92 Ų9254.5 Ų54.547%0.47229%0.289SS..SBendtrans-134.1118.3-179.8-52.4176.6000108.7Y324 L476 T480Y324-I482 HydrophobicContact CE2-CG1 4.34Å; L476-I482 HydrophobicContact CD1-CD1 3.65Å; L476-I482 HydrophobicContact CD2-CD1 3.94Å; L476-I482 HydrophobicContact CG-CD1 4.34Å; T480-I482 HydrophobicContact CG2-CD1 4.42Å; T480-I482 HydrophobicContact CG2-CG1 4.11Å; T480-I482 PolarHBondContact O-N 2.94Å
483P93.5Very high92.5Very high108 Ų10854.8 Ų54.870%0.70129%0.29SS*.SBendcis-70.8153.7-1032.3-35.6000111.7
484L94.9Very high92.1Very high15 Ų1551.5 Ų51.58%0.07928%0.279CS..PPolyproline II helixtrans-55.8138.6174.7-67.4174.6000112Y321 Y324 Y373 E481 Y486 T495 I499Y321-L484 HydrophobicContact CD1-CD1 3.86Å; Y321-L484 HydrophobicContact CE1-CD1 3.83Å; Y324-L484 HydrophobicContact CD1-CD1 3.83Å; Y324-L484 HydrophobicContact CD1-CG 4.39Å; Y324-L484 HydrophobicContact CD2-CD1 4.11Å; Y324-L484 HydrophobicContact CD2-CD2 4.06Å; Y324-L484 HydrophobicContact CD2-CG 4.16Å; Y324-L484 HydrophobicContact CE1-CD1 3.87Å; Y324-L484 HydrophobicContact CE1-CG 4.01Å; Y324-L484 HydrophobicContact CE2-CD1 4.13Å; Y324-L484 HydrophobicContact CE2-CD2 3.79Å; Y324-L484 HydrophobicContact CE2-CG 3.73Å; Y324-L484 HydrophobicContact CG-CD1 3.97Å; Y324-L484 HydrophobicContact CG-CG 4.48Å; Y373-L484 HydrophobicContact CE1-CD1 4.31Å; E481-L484 WeakPolarHBondContact O-CD2 3.47Å; L484-Y486 HydrophobicContact CB-CE1 4.39Å; L484-T495 HydrophobicContact CD1-CG2 4.23Å; L484-T495 HydrophobicContact CD2-CG2 4.41Å; L484-I499 HydrophobicContact CD1-CD1 3.98Å; L484-I499 HydrophobicContact CD2-CD1 4.39Å; L484-I499 HydrophobicContact CD2-CG1 4.09Å
485K94.1Very high91.8Very high127 Ų12751.9 Ų51.955%0.55228%0.281SS*.PPolyproline II helixtrans-92.5137.6168.8-67.4-177.2-171.9125.80110.8E481 T495 V496E481-K485 WeakPolarHBondContact OE1-CD 3.4Å; E481-K485 WeakPolarHBondContact OE1-CE 3.46Å; E481-K485 WeakPolarHBondContact OE1-CG 3.42Å; E481-K485 IonicContact OE1-NZ 2.68Å; E481-K485 PolarHBondContact OE1-NZ 3.01Å; E481-K485 PolarHBondContact OE2-N 2.87Å; K485-T495 CarbonylContact O-C 3.52Å; K485-T495 VanDerWaalsContact O-CA 3.26Å; K485-T495 WeakPolarHBondContact O-CA 3.41Å; K485-V496 HydrophobicContact CB-CB 4.22Å; K485-V496 HydrophobicContact CB-CG2 4.3Å; K485-V496 PolarHBondContact O-N 2.87Å
486Y93.9Very high91.3Very high64 Ų6454.2 Ų54.225%0.25130%0.295SS..BIsolated β-bridgetrans-104.9143.2-180-55.2-71.5000112.7Y321 Y373 L484 P488 L493 G494Y321-Y486 HydrophobicContact CE1-CE1 4.12Å; Y373-Y486 WeakPolarHBondContact CE1-OH 3.41Å; L484-Y486 HydrophobicContact CB-CE1 4.39Å; Y486-P488 WeakPolarHBondContact O-CD 3.47Å; Y486-L493 HydrophobicContact CD1-CD1 3.57Å; Y486-L493 HydrophobicContact CD1-CG 3.84Å; Y486-L493 HydrophobicContact CD2-CD1 4.12Å; Y486-L493 HydrophobicContact CE1-CD1 3.9Å; Y486-L493 HydrophobicContact CE1-CD2 4.11Å; Y486-L493 HydrophobicContact CE1-CG 3.87Å; Y486-L493 HydrophobicContact CE2-CD1 4.42Å; Y486-L493 HydrophobicContact CG-CD1 3.69Å; Y486-L493 HydrophobicContact CG-CG 4.46Å; Y486-G494 CarbonylContact C-O 3.47Å; Y486-G494 VanDerWaalsContact CA-O 3.3Å; Y486-G494 WeakPolarHBondContact CA-O 3.2Å
487S90.9Very high90.7Very high30 Ų3053.8 Ų53.821%0.2131%0.306CS..  trans-77.5115.8-176.7177.60000111V51 M489 S490 G494V51-S487 WeakPolarHBondContact CG1-O 3.44Å; S487-M489 PolarHBondContact O-N 3.49Å; S487-M489 VanDerWaalsContact O-N 3.15Å; S487-M489 PolarHBondContact OG-N 2.73Å; S487-S490 PolarHBondContact O-N 2.59Å; S487-G494 PolarHBondContact N-O 3.03Å
488P87.9Confident90.4Very high27 Ų2753.7 Ų53.718%0.17531%0.307CS..THydrogen-bonded Turntrans-67.4-15.7177.929.1-35.5000112.6R47 R50 Y486R47-P488 VanDerWaalsContact CA-O 3.24Å; R47-P488 WeakPolarHBondContact CA-O 3.36Å; R50-P488 WeakPolarHBondContact O-CB 3.45Å; Y486-P488 WeakPolarHBondContact O-CD 3.47Å
489M82.7Confident90.5Very high54 Ų5445.9 Ų45.927%0.26627%0.265SS..THydrogen-bonded Turntrans-82.1-22.6179.9-69.7-61-63.600113.1R47 M217 S487R47-M489 HydrophobicContact CB-SD 3.91Å; R47-M489 PolarHBondContact NH1-O 2.88Å; R47-M489 VanDerWaalsContact O-SD 3.41Å; M217-M489 HydrophobicContact CE-CE 3.86Å; S487-M489 PolarHBondContact O-N 3.49Å; S487-M489 VanDerWaalsContact O-N 3.15Å; S487-M489 PolarHBondContact OG-N 2.73Å
490S81.6Confident90.6Very high20 Ų2046.3 Ų46.314%0.1426%0.258CS..  trans-75.3144.4-177.8-176.80000111.7S487 V492S487-S490 PolarHBondContact O-N 2.59Å; S490-V492 VanDerWaalsContact CB-O 3.22Å; S490-V492 WeakPolarHBondContact CB-O 3.37Å; S490-V492 PolarHBondContact OG-N 3.4Å; S490-V492 PolarHBondContact OG-O 3.02Å
491I77.8Confident90.7Very high79 Ų7945.5 Ų45.541%0.40525%0.253SS..SBendtrans-85.4-24.3174.6-55.4175.1000110.7R47 M52R47-I491 VanDerWaalsContact NH2-CG1 3.33Å; M52-I491 HydrophobicContact CE-CG2 3.99Å; M52-I491 WeakPolarHBondContact CE-O 3.28Å
492V88.1Confident90.7Very high21 Ų2145.7 Ų45.713%0.12725%0.251CS..SBendtrans-103.3164.8170.3-64.30000110.1F214 E313 L375 V376 S490 G494F214-V492 HydrophobicContact CD1-CG2 4.33Å; F214-V492 HydrophobicContact CE1-CG1 4.47Å; F214-V492 HydrophobicContact CE1-CG2 4.32Å; E313-V492 HydrophobicContact CG-CG2 4.26Å; L375-V492 CarbonylContact O-C 3.51Å; L375-V492 WeakPolarHBondContact O-CA 3.15Å; L375-V492 WeakPolarHBondContact O-CB 3.3Å; V376-V492 HydrophobicContact CG2-CG1 4.45Å; S490-V492 VanDerWaalsContact CB-O 3.22Å; S490-V492 WeakPolarHBondContact CB-O 3.37Å; S490-V492 PolarHBondContact OG-N 3.4Å; S490-V492 PolarHBondContact OG-O 3.02Å; V492-G494 VanDerWaalsContact C-N 3.32Å; V492-G494 PolarHBondContact O-N 2.92Å
493L92.1Very high90.9Very high8 Ų841.5 Ų41.54%0.04223%0.23CC..SBendtrans-66.791173.1-17169.9000110.3H53 Y321 Y373 L375 Y486H53-L493 HydrophobicContact CB-CD1 4.47Å; Y321-L493 PolarHBondContact OH-O 3.26Å; Y373-L493 HydrophobicContact CD1-CD2 4.18Å; L375-L493 HydrophobicContact CD2-CB 4.4Å; L375-L493 PolarHBondContact O-N 3.49Å; Y486-L493 HydrophobicContact CD1-CD1 3.57Å; Y486-L493 HydrophobicContact CD1-CG 3.84Å; Y486-L493 HydrophobicContact CD2-CD1 4.12Å; Y486-L493 HydrophobicContact CE1-CD1 3.9Å; Y486-L493 HydrophobicContact CE1-CD2 4.11Å; Y486-L493 HydrophobicContact CE1-CG 3.87Å; Y486-L493 HydrophobicContact CE2-CD1 4.42Å; Y486-L493 HydrophobicContact CG-CD1 3.69Å; Y486-L493 HydrophobicContact CG-CG 4.46Å
494G89.5Confident91Very high3 Ų338.8 Ų38.83%0.03121%0.208CC..  trans-114.8147.4177.900000111.2Y486 S487 V492Y486-G494 CarbonylContact C-O 3.47Å; Y486-G494 VanDerWaalsContact CA-O 3.3Å; Y486-G494 WeakPolarHBondContact CA-O 3.2Å; S487-G494 PolarHBondContact N-O 3.03Å; V492-G494 VanDerWaalsContact C-N 3.32Å; V492-G494 PolarHBondContact O-N 2.92Å
495T91.4Very high90.9Very high9 Ų943.1 Ų43.16%0.05522%0.223CC..BIsolated β-bridgetrans-74.3152.1176.155.80000113.1K176 Y321 L484 K485 G497 I499K176-T495 WeakPolarHBondContact CD-OG1 3.49Å; K176-T495 PolarHBondContact NZ-OG1 3.05Å; Y321-T495 HydrophobicContact CE1-CG2 3.72Å; L484-T495 HydrophobicContact CD1-CG2 4.23Å; L484-T495 HydrophobicContact CD2-CG2 4.41Å; K485-T495 CarbonylContact O-C 3.52Å; K485-T495 VanDerWaalsContact O-CA 3.26Å; K485-T495 WeakPolarHBondContact O-CA 3.41Å; T495-G497 PolarHBondContact OG1-O 2.79Å; T495-I499 HydrophobicContact CG2-CD1 4.09Å; T495-I499 HydrophobicContact CG2-CG1 4.07Å
496V87.6Confident90.6Very high74 Ų7443.1 Ų43.145%0.44823%0.228SC..SBendtrans-74.7121.1158.2179.50000106.9K485K485-V496 HydrophobicContact CB-CB 4.22Å; K485-V496 HydrophobicContact CB-CG2 4.3Å; K485-V496 PolarHBondContact O-N 2.87Å
497G84.9Confident90.4Very high56 Ų5642.1 Ų42.158%0.57723%0.227SC*.SBendtrans71.5-164.8-172.200000113.5T495T495-G497 PolarHBondContact OG1-O 2.79Å
498G90.4Very high90.4Very high12 Ų1242.7 Ų42.712%0.12423%0.228CC..  trans-92177.5178.100000113.2E174E174-G498 WeakPolarHBondContact OE1-CA 3.33Å
499I96.9Very high90.6Very high2 Ų243.6 Ų43.61%0.0123%0.231CC..  trans-108.7113.8167.7-60.8-178.7000106.6E174 I175 Y321 Y324 L484 T495 L501E174-I499 CarbonylContact C-O 3.57Å; I175-I499 WeakPolarHBondContact CB-O 3.38Å; I175-I499 PolarHBondContact N-O 3.03Å; Y321-I499 HydrophobicContact CD1-CD1 3.88Å; Y321-I499 HydrophobicContact CE1-CD1 3.99Å; Y324-I499 HydrophobicContact CD2-CG2 4.13Å; L484-I499 HydrophobicContact CD1-CD1 3.98Å; L484-I499 HydrophobicContact CD2-CD1 4.39Å; L484-I499 HydrophobicContact CD2-CG1 4.09Å; T495-I499 HydrophobicContact CG2-CD1 4.09Å; T495-I499 HydrophobicContact CG2-CG1 4.07Å; I499-L501 HydrophobicContact CG2-CD1 4.36Å; I499-L501 HydrophobicContact CG2-CD2 4.46Å; I499-L501 HydrophobicContact CG2-CG 4.14Å
500Y97.8Very high91Very high95 Ų9542.9 Ų42.937%0.37323%0.229SC..EExtended strand (participates in β ladder)trans-100.4125.4179.6-64-92.3000109.6V172 L173 E174 T479 T480V172-Y500 HydrophobicContact CG1-CD1 4.42Å; L173-Y500 WeakPolarHBondContact O-CA 3.35Å; E174-Y500 HydrophobicContact CB-CD1 3.98Å; E174-Y500 HydrophobicContact CB-CE1 3.62Å; E174-Y500 HydrophobicContact CG-CD1 4.28Å; E174-Y500 HydrophobicContact CG-CE1 3.82Å; E174-Y500 HydrophobicContact CG-CE2 4.28Å; T479-Y500 VanDerWaalsContact OG1-CB 3.26Å; T479-Y500 WeakPolarHBondContact OG1-CB 3.09Å; T480-Y500 WeakPolarHBondContact CB-O 3.5Å; T480-Y500 PolarHBondContact OG1-O 2.91Å
501L97.9Very high91.6Very high0 Ų044.4 Ų44.40%023%0.234CC..EExtended strand (participates in β ladder)trans-132.9153.6176.6-60.1176.2000109.7V172 L173 I175 L323 A327 V474 L476 T480 I499V172-L501 WeakPolarHBondContact CA-O 3.32Å; L173-L501 PolarHBondContact N-O 2.86Å; L173-L501 PolarHBondContact O-N 2.82Å; L173-L501 VanDerWaalsContact O-N 3.1Å; I175-L501 HydrophobicContact CD1-CB 4.34Å; I175-L501 HydrophobicContact CG1-CB 3.77Å; I175-L501 HydrophobicContact CG1-CD1 3.88Å; I175-L501 HydrophobicContact CG1-CG 3.89Å; L323-L501 HydrophobicContact CB-CD1 4.06Å; L323-L501 WeakPolarHBondContact O-CD1 3.3Å; A327-L501 HydrophobicContact CB-CD1 4.05Å; A327-L501 HydrophobicContact CB-CD2 3.78Å; A327-L501 HydrophobicContact CB-CG 4.5Å; V474-L501 HydrophobicContact CG1-CB 3.61Å; V474-L501 HydrophobicContact CG1-CD1 3.44Å; V474-L501 VanDerWaalsContact CG1-CD1 3.44Å; V474-L501 HydrophobicContact CG1-CG 4.09Å; L476-L501 HydrophobicContact CD2-CD2 4.27Å; T480-L501 HydrophobicContact CG2-CD2 3.83Å; I499-L501 HydrophobicContact CG2-CD1 4.36Å; I499-L501 HydrophobicContact CG2-CD2 4.46Å; I499-L501 HydrophobicContact CG2-CG 4.14Å
502R97.2Very high92.5Very high63 Ų6342.1 Ų42.124%0.23822%0.223CC..EExtended strand (participates in β ladder)trans-80.9133.7168.5-177.4174.2-58.6-77.2-2.1108.9N169 A171 V474 S475 C477 E504N169-R502 WeakPolarHBondContact O-CD 3.3Å; N169-R502 PolarHBondContact O-NH1 3.47Å; A171-R502 WeakPolarHBondContact O-CA 3.35Å; V474-R502 CarbonylContact C-O 3.57Å; V474-R502 VanDerWaalsContact CA-O 3.31Å; V474-R502 WeakPolarHBondContact CA-O 3.26Å; S475-R502 PolarHBondContact N-O 3.03Å; S475-R502 PolarHBondContact O-N 2.87Å; C477-R502 HydrophobicContact CB-CB 4.2Å; R502-E504 WeakPolarHBondContact CD-OE1 3.46Å; R502-E504 HydrophobicContact CG-CG 4.19Å
503V97.6Very high92.9Very high4 Ų443.6 Ų43.62%0.02423%0.229CC..EExtended strand (participates in β ladder)trans-123.3124.5178.6-174.20000108.3I160 V164 G170 A171 L173 I175 F472 R473 V474I160-V503 HydrophobicContact CG2-CG1 4.4Å; V164-V503 WeakPolarHBondContact CG1-O 3.26Å; V164-V503 HydrophobicContact CG2-CB 4.02Å; V164-V503 HydrophobicContact CG2-CG1 3.9Å; G170-V503 CarbonylContact C-O 3.03Å; G170-V503 VanDerWaalsContact CA-O 3.29Å; G170-V503 WeakPolarHBondContact CA-O 3.28Å; A171-V503 PolarHBondContact N-O 2.8Å; A171-V503 PolarHBondContact O-N 3.08Å; L173-V503 HydrophobicContact CB-CG2 4.35Å; L173-V503 HydrophobicContact CD1-CB 4.19Å; L173-V503 HydrophobicContact CD1-CG2 3.95Å; L173-V503 HydrophobicContact CG-CB 4.49Å; L173-V503 HydrophobicContact CG-CG2 4.18Å; I175-V503 HydrophobicContact CD1-CG2 3.9Å; F472-V503 HydrophobicContact CB-CG1 3.7Å; F472-V503 HydrophobicContact CD1-CG1 3.74Å; F472-V503 HydrophobicContact CG-CG1 3.86Å; R473-V503 WeakPolarHBondContact O-CA 3.39Å; V474-V503 HydrophobicContact CG2-CG2 4.45Å
504E95.6Very high92.9Very high52 Ų5246.3 Ų46.324%0.24324%0.244CC..EExtended strand (participates in β ladder)trans-123.6136.6-177-69.4173.5169.200109.7N169 F472 R473 R502N169-E504 WeakPolarHBondContact CA-OE1 3.09Å; F472-E504 CarbonylContact C-O 3.53Å; F472-E504 WeakPolarHBondContact CA-O 3.42Å; F472-E504 WeakPolarHBondContact CB-O 3.17Å; R473-E504 PolarHBondContact N-O 3.47Å; R473-E504 PolarHBondContact O-N 2.99Å; R502-E504 WeakPolarHBondContact CD-OE1 3.46Å; R502-E504 HydrophobicContact CG-CG 4.19Å
505R92.8Very high93.2Very high105 Ų10549.9 Ų49.940%0.39626%0.262SS..EExtended strand (participates in β ladder)trans-71.1139.9171.5-63.2-173.8-167.9-176.111.5109.3T161 V164 F472T161-R505 PolarHBondContact O-NH2 3.05Å; V164-R505 HydrophobicContact CG1-CG 3.97Å; V164-R505 PolarHBondContact O-NE 3.49Å; V164-R505 PolarHBondContact O-NH2 3.17Å; F472-R505 HydrophobicContact CD1-CG 4.03Å; F472-R505 HydrophobicContact CE1-CG 3.74Å
506I88.3Confident93.4Very high127 Ų12753.6 Ų53.665%0.65128%0.28SS*.  trans-106.70174.251.8167.8000111.9R471 R473R471-I506 VanDerWaalsContact C-CG1 3.41Å; R471-I506 VanDerWaalsContact O-CG1 3.3Å; R471-I506 WeakPolarHBondContact O-CG1 3.35Å; R471-I506 PolarHBondContact O-N 3.49Å; R473-I506 HydrophobicContact CB-CG2 3.96Å

Retrieved 506 of 506 residues in 656.5 ms (Link to these results)