A0A075E721_DROME Loading...

NADH-ubiquinone oxidoreductase chain 4

Core subunit of the mitochondrial membrane respiratory chain NADH dehydrogenase (Complex I) that is believed to belong to the minimal assembly required for catalysis. Complex I functions in the transfer of electrons from NADH to the respiratory chain. The immediate electron acceptor for the enzyme is believed to be ubiquinone. Core subunit of the mitochondrial membrane respiratory chain NADH dehydrogenase (Complex I) which catalyzes electron transfer from NADH through the respiratory chain, using ubiquinone as an electron acceptor. Essential for the catalytic activity and assembly of complex I.

AlphaFold DB (P18931), UniProt , Accession A0A075E721, Species DROME (Drosophila melanogaster, Fruit fly), Gene ND4, Length 446 aa.

Structure Viewer

Loading PAE data...

(Predicted Aligned Error values between residue pairs)

Download Structure PDB PAE Table

Site	Residue	pLDDT	pLDDT confidence	pLDDT₁₀	pLDDT10 confidence	SASA	SASA [Å²]	SASA₁₀	SASA10 [Å²]	RSA	RSA unformatted	RSA₁₀	RSA10 unformatted	Surface	Surface10 (not used)	Disorder (not used)	Disorder	Sec. str.	Secondary structure	Isomer	Phi (φ)	Psi (ψ)	Omega (ω)	Chi 1 (χ₁)	Chi 2 (χ₂)	Chi 3 (χ₃)	Chi 4 (χ₄)	Chi 5 (χ₅)	Tau (τ)	Contacts (colored by PAE)	Contact details
1	M	85.2	Confident	91.6	Very high	12 Å²	12	60.8 Å²	60.8	6%	0.059	28%	0.28	C	S	.	.				0	-50.3	0	-68	-48.2	-79.2	0	0	116.7	K3 I4 I5 F35 E47 L52 C54 I62 I101	M1-K3 PolarHBondContact O-N 3.34Å; M1-K3 VanDerWaalsContact O-N 3.1Å; M1-I4 HydrophobicContact CE-CD1 4.3Å; M1-I4 PolarHBondContact O-N 3.5Å; M1-I4 HydrophobicContact SD-CD1 3.91Å; M1-I5 PolarHBondContact O-N 3.47Å; M1-F35 HydrophobicContact SD-CE2 4.3Å; M1-E47 PolarHBondContact N-OE2 3.49Å; M1-L52 HydrophobicContact CB-CB 4.21Å; M1-L52 HydrophobicContact CB-CD1 4.46Å; M1-C54 VanDerWaalsContact CE-SG 3.54Å; M1-C54 VanDerWaalsContact CG-SG 3.5Å; M1-C54 HydrophobicContact SD-CB 4.44Å; M1-C54 PolarHBondContact SD-SG 2.94Å; M1-I62 HydrophobicContact CE-CD1 3.71Å; M1-I101 HydrophobicContact CE-CG2 3.73Å
2	L	87.7	Confident	91.7	Very high	56 Å²	56	59.8 Å²	59.8	29%	0.293	28%	0.277	S	S	.	.	H	α-helix	trans	-53.4	-35.5	-176.7	-72.8	167.8	0	0	0	114.6	I4 I5 F6 S49 Y50 L52	L2-I4 VanDerWaalsContact C-N 3.27Å; L2-I4 PolarHBondContact O-N 3.12Å; L2-I5 PolarHBondContact O-N 3.21Å; L2-F6 HydrophobicContact CB-CD2 4.22Å; L2-F6 HydrophobicContact CB-CE2 4.16Å; L2-F6 HydrophobicContact CD2-CE2 4.46Å; L2-F6 WeakPolarHBondContact O-CD2 3.37Å; L2-F6 PolarHBondContact O-N 3.25Å; L2-S49 WeakPolarHBondContact CG-OG 3.16Å; L2-Y50 HydrophobicContact CD1-CD2 4.23Å; L2-Y50 HydrophobicContact CD1-CE2 4.1Å; L2-L52 HydrophobicContact CD2-CD1 4.13Å
3	K	90.3	Very high	91.7	Very high	175 Å²	175	61.1 Å²	61.1	76%	0.761	29%	0.294	S	S	*	.	H	α-helix	trans	-53.5	-41.7	176.4	-63.4	179.4	-177.7	175.5	0	112.7	M1 F7	M1-K3 PolarHBondContact O-N 3.34Å; M1-K3 VanDerWaalsContact O-N 3.1Å; K3-F7 PolarHBondContact O-N 3.07Å; K3-F7 VanDerWaalsContact O-N 3.12Å
4	I	90.5	Very high	91.6	Very high	18 Å²	18	63.3 Å²	63.3	9%	0.092	30%	0.302	C	S	.	.	H	α-helix	trans	-71.7	-43.6	-179.5	-58.4	167	0	0	0	110.3	M1 L2 F7 L8 I31 F35 I101	M1-I4 HydrophobicContact CE-CD1 4.3Å; M1-I4 PolarHBondContact O-N 3.5Å; M1-I4 HydrophobicContact SD-CD1 3.91Å; L2-I4 VanDerWaalsContact C-N 3.27Å; L2-I4 PolarHBondContact O-N 3.12Å; I4-F7 WeakPolarHBondContact O-CB 3.49Å; I4-F7 PolarHBondContact O-N 3.36Å; I4-L8 WeakPolarHBondContact O-CG 3.27Å; I4-L8 PolarHBondContact O-N 3.44Å; I4-I31 HydrophobicContact CG2-CG2 3.99Å; I4-F35 HydrophobicContact CD1-CD2 3.26Å; I4-F35 HydrophobicContact CD1-CE2 3.53Å; I4-F35 HydrophobicContact CD1-CG 4.28Å; I4-F35 HydrophobicContact CG1-CD2 4.47Å; I4-I101 HydrophobicContact CG2-CD1 3.82Å
5	I	92.2	Very high	91.6	Very high	20 Å²	20	59.1 Å²	59.1	10%	0.103	28%	0.282	C	S	.	.	H	α-helix	trans	-63.2	-45.6	179.7	-63.7	166.3	0	0	0	110.3	M1 L2 F7 L8 L9 L52 L102	M1-I5 PolarHBondContact O-N 3.47Å; L2-I5 PolarHBondContact O-N 3.21Å; I5-F7 VanDerWaalsContact C-N 3.34Å; I5-F7 PolarHBondContact O-N 3.07Å; I5-L8 PolarHBondContact O-N 2.94Å; I5-L9 HydrophobicContact CG2-CD1 4.14Å; I5-L9 WeakPolarHBondContact O-CG 3.34Å; I5-L9 PolarHBondContact O-N 3.08Å; I5-L52 HydrophobicContact CD1-CD1 3.33Å; I5-L52 HydrophobicContact CD1-CD2 4.32Å; I5-L52 HydrophobicContact CD1-CG 4.48Å; I5-L102 HydrophobicContact CD1-CD2 3.72Å; I5-L102 HydrophobicContact CG1-CD2 4.43Å
6	F	92.6	Very high	91.5	Very high	107 Å²	107	62.2 Å²	62.2	47%	0.469	29%	0.294	S	S	.	.	H	α-helix	trans	-60.7	-43.5	175.8	-80.2	-59.6	0	0	0	111.9	L2 L8 L9 F10	L2-F6 HydrophobicContact CB-CD2 4.22Å; L2-F6 HydrophobicContact CB-CE2 4.16Å; L2-F6 HydrophobicContact CD2-CE2 4.46Å; L2-F6 WeakPolarHBondContact O-CD2 3.37Å; L2-F6 PolarHBondContact O-N 3.25Å; F6-L8 VanDerWaalsContact C-N 3.31Å; F6-L8 PolarHBondContact O-N 3.04Å; F6-L9 HydrophobicContact CD1-CD1 4.4Å; F6-L9 PolarHBondContact O-N 3.17Å; F6-F10 HydrophobicContact CB-CD2 4.47Å; F6-F10 HydrophobicContact CB-CE2 4.29Å; F6-F10 WeakPolarHBondContact O-CD2 3.42Å; F6-F10 PolarHBondContact O-N 2.9Å
7	F	93.7	Very high	91.4	Very high	56 Å²	56	63.6 Å²	63.6	25%	0.246	30%	0.303	C	S	.	.	H	α-helix	trans	-56.8	-45.8	175.5	-171.1	-76.5	0	0	0	111.7	K3 I4 I5 L9 F10 L11 M27 F30 I31	K3-F7 PolarHBondContact O-N 3.07Å; K3-F7 VanDerWaalsContact O-N 3.12Å; I4-F7 WeakPolarHBondContact O-CB 3.49Å; I4-F7 PolarHBondContact O-N 3.36Å; I5-F7 VanDerWaalsContact C-N 3.34Å; I5-F7 PolarHBondContact O-N 3.07Å; F7-L9 PolarHBondContact O-N 3.2Å; F7-F10 PolarHBondContact O-N 3.44Å; F7-L11 HydrophobicContact CD1-CD1 3.95Å; F7-L11 HydrophobicContact CD1-CG 4Å; F7-L11 HydrophobicContact CE1-CD1 3.64Å; F7-L11 HydrophobicContact CE1-CD2 3.99Å; F7-L11 HydrophobicContact CE1-CG 3.76Å; F7-L11 PolarHBondContact O-N 3.2Å; F7-L11 VanDerWaalsContact O-N 3.11Å; F7-M27 HydrophobicContact CE1-CB 4.2Å; F7-M27 HydrophobicContact CZ-CB 4.16Å; F7-M27 HydrophobicContact CZ-SD 4.08Å; F7-F30 HydrophobicContact CE2-CD1 4.39Å; F7-F30 HydrophobicContact CZ-CD1 4.37Å; F7-I31 HydrophobicContact CD1-CD1 3.1Å; F7-I31 HydrophobicContact CD1-CG1 3.17Å; F7-I31 HydrophobicContact CE1-CD1 3.25Å; F7-I31 HydrophobicContact CE1-CG1 3.09Å; F7-I31 HydrophobicContact CE2-CG1 4.46Å; F7-I31 HydrophobicContact CG-CD1 4.16Å; F7-I31 HydrophobicContact CG-CG1 3.92Å; F7-I31 HydrophobicContact CZ-CD1 4.37Å; F7-I31 HydrophobicContact CZ-CG1 3.79Å
8	L	93.6	Very high	90.7	Very high	1 Å²	1	66.8 Å²	66.8	1%	0.005	32%	0.322	C	S	.	.	H	α-helix	trans	-64.1	-39.3	177.9	-70.1	-179.8	0	0	0	113.1	I4 I5 F6 F10 L11 M28 I31 L97 L98 I101	I4-L8 WeakPolarHBondContact O-CG 3.27Å; I4-L8 PolarHBondContact O-N 3.44Å; I5-L8 PolarHBondContact O-N 2.94Å; F6-L8 VanDerWaalsContact C-N 3.31Å; F6-L8 PolarHBondContact O-N 3.04Å; L8-F10 VanDerWaalsContact C-N 3.32Å; L8-F10 PolarHBondContact O-N 3.39Å; L8-L11 HydrophobicContact CD2-CD1 4.18Å; L8-L11 WeakPolarHBondContact O-CB 3.19Å; L8-L11 PolarHBondContact O-N 2.64Å; L8-L11 VanDerWaalsContact O-N 3.14Å; L8-M28 HydrophobicContact CD2-SD 3.91Å; L8-I31 HydrophobicContact CD2-CD1 3.47Å; L8-I31 VanDerWaalsContact CD2-CD1 3.47Å; L8-I31 HydrophobicContact CG-CD1 4.27Å; L8-L97 HydrophobicContact CD1-CD2 3.84Å; L8-L97 HydrophobicContact CD1-CG 3.93Å; L8-L97 HydrophobicContact CD2-CD2 3.45Å; L8-L97 VanDerWaalsContact CD2-CD2 3.45Å; L8-L97 HydrophobicContact CD2-CG 4.38Å; L8-L97 HydrophobicContact CG-CD2 4.32Å; L8-L98 HydrophobicContact CB-CD1 4.47Å; L8-L98 HydrophobicContact CD1-CB 4.46Å; L8-I101 HydrophobicContact CD1-CD1 3.47Å; L8-I101 VanDerWaalsContact CD1-CD1 3.47Å
9	L	94.2	Very high	90.3	Very high	77 Å²	77	70.3 Å²	70.3	40%	0.403	34%	0.343	S	S	.	.	H	α-helix	trans	-62	-40.8	174.8	-71.3	170.3	0	0	0	111.4	I5 F6 F7 L11 I12 L98	I5-L9 HydrophobicContact CG2-CD1 4.14Å; I5-L9 WeakPolarHBondContact O-CG 3.34Å; I5-L9 PolarHBondContact O-N 3.08Å; F6-L9 HydrophobicContact CD1-CD1 4.4Å; F6-L9 PolarHBondContact O-N 3.17Å; F7-L9 PolarHBondContact O-N 3.2Å; L9-L11 PolarHBondContact O-N 3.1Å; L9-I12 HydrophobicContact CD2-CD1 4.04Å; L9-I12 WeakPolarHBondContact O-CB 2.95Å; L9-I12 PolarHBondContact O-N 3.42Å; L9-L98 HydrophobicContact CD2-CD1 3.65Å; L9-L98 HydrophobicContact CG-CD1 3.98Å
10	F	93.6	Very high	90.2	Very high	142 Å²	142	69.5 Å²	69.5	62%	0.623	34%	0.339	S	S	*	.	H	α-helix	trans	-71.3	-14.6	175.9	-71.4	-60.3	0	0	0	114.1	F6 F7 L8 P13 F14	F6-F10 HydrophobicContact CB-CD2 4.47Å; F6-F10 HydrophobicContact CB-CE2 4.29Å; F6-F10 WeakPolarHBondContact O-CD2 3.42Å; F6-F10 PolarHBondContact O-N 2.9Å; F7-F10 PolarHBondContact O-N 3.44Å; L8-F10 VanDerWaalsContact C-N 3.32Å; L8-F10 PolarHBondContact O-N 3.39Å; F10-P13 WeakPolarHBondContact O-CD 3.5Å; F10-F14 VanDerWaalsContact O-CD2 3.3Å; F10-F14 WeakPolarHBondContact O-CD2 3.43Å
11	L	93.6	Very high	90.3	Very high	5 Å²	5	66.5 Å²	66.5	3%	0.026	32%	0.324	C	S	.	.	H	α-helix	trans	-77.7	-19.8	171.4	-73.7	-179.2	0	0	0	113.9	F7 L8 L9 F14 M27 M28 I31 I94	F7-L11 HydrophobicContact CD1-CD1 3.95Å; F7-L11 HydrophobicContact CD1-CG 4Å; F7-L11 HydrophobicContact CE1-CD1 3.64Å; F7-L11 HydrophobicContact CE1-CD2 3.99Å; F7-L11 HydrophobicContact CE1-CG 3.76Å; F7-L11 PolarHBondContact O-N 3.2Å; F7-L11 VanDerWaalsContact O-N 3.11Å; L8-L11 HydrophobicContact CD2-CD1 4.18Å; L8-L11 WeakPolarHBondContact O-CB 3.19Å; L8-L11 PolarHBondContact O-N 2.64Å; L8-L11 VanDerWaalsContact O-N 3.14Å; L9-L11 PolarHBondContact O-N 3.1Å; L11-F14 HydrophobicContact CD2-CD2 4.36Å; L11-F14 PolarHBondContact O-N 3.06Å; L11-M27 HydrophobicContact CD1-CB 4.29Å; L11-M27 HydrophobicContact CD2-CB 3.56Å; L11-M27 HydrophobicContact CD2-CG 3.95Å; L11-M28 HydrophobicContact CD1-CG 4.2Å; L11-M28 HydrophobicContact CD1-SD 3.81Å; L11-I31 HydrophobicContact CD1-CD1 4.02Å; L11-I94 HydrophobicContact CB-CD1 3.73Å
12	I	93.8	Very high	90.6	Very high	48 Å²	48	70.5 Å²	70.5	25%	0.246	34%	0.338	C	S	.	.	T	Hydrogen-bonded Turn	trans	-60.2	-47.3	-177.1	-61	169.6	0	0	0	111.8	L9 F14 C15 F16 L91 I94	L9-I12 HydrophobicContact CD2-CD1 4.04Å; L9-I12 WeakPolarHBondContact O-CB 2.95Å; L9-I12 PolarHBondContact O-N 3.42Å; I12-F14 VanDerWaalsContact C-N 3.28Å; I12-F14 PolarHBondContact O-N 2.99Å; I12-C15 VanDerWaalsContact O-CB 3.32Å; I12-C15 WeakPolarHBondContact O-CB 3.43Å; I12-C15 PolarHBondContact O-N 3.21Å; I12-C15 VanDerWaalsContact O-N 3.13Å; I12-F16 HydrophobicContact CG2-CE2 4.27Å; I12-L91 HydrophobicContact CG2-CD1 4.42Å; I12-I94 HydrophobicContact CG1-CG2 3.96Å
13	P	91.9	Very high	90.9	Very high	77 Å²	77	71.3 Å²	71.3	50%	0.5	34%	0.342	S	S	.	.	G	3₁₀ helix	trans	-57.7	-37	176.1	-26.1	34.9	0	0	0	114	F10 C15 F16	F10-P13 WeakPolarHBondContact O-CD 3.5Å; P13-C15 PolarHBondContact O-N 3.35Å; P13-F16 PolarHBondContact O-N 2.62Å
14	F	90.2	Very high	91.1	Very high	92 Å²	92	63 Å²	63	40%	0.404	31%	0.306	S	S	.	.	G	3₁₀ helix	trans	-64	-23.9	179.7	-71.8	-76.4	0	0	0	113.1	F10 L11 I12 F16 I17 M20 V24	F10-F14 VanDerWaalsContact O-CD2 3.3Å; F10-F14 WeakPolarHBondContact O-CD2 3.43Å; L11-F14 HydrophobicContact CD2-CD2 4.36Å; L11-F14 PolarHBondContact O-N 3.06Å; I12-F14 VanDerWaalsContact C-N 3.28Å; I12-F14 PolarHBondContact O-N 2.99Å; F14-F16 PolarHBondContact O-N 3.23Å; F14-I17 HydrophobicContact CD1-CD1 3.96Å; F14-I17 HydrophobicContact CE1-CD1 4.5Å; F14-I17 PolarHBondContact O-N 2.95Å; F14-M20 HydrophobicContact CD1-CE 4.28Å; F14-V24 HydrophobicContact CB-CG2 4.24Å
15	C	91	Very high	91.3	Very high	0 Å²	0	62.9 Å²	62.9	0%	0	31%	0.305	C	S	.	.	G	3₁₀ helix	trans	-66.2	-25.4	177.3	-65.7	0	0	0	0	113.6	I12 P13 N87 L90 I94	I12-C15 VanDerWaalsContact O-CB 3.32Å; I12-C15 WeakPolarHBondContact O-CB 3.43Å; I12-C15 PolarHBondContact O-N 3.21Å; I12-C15 VanDerWaalsContact O-N 3.13Å; P13-C15 PolarHBondContact O-N 3.35Å; C15-N87 PolarHBondContact O-OD1 2.93Å; C15-L90 HydrophobicContact CB-CB 4.04Å; C15-I94 WeakPolarHBondContact SG-CD1 3.37Å
16	F	90.2	Very high	91.4	Very high	109 Å²	109	66.6 Å²	66.6	48%	0.478	32%	0.324	S	S	.	.	G	3₁₀ helix	trans	-90.7	-12.7	-177.8	-65.4	-72.6	0	0	0	113.2	I12 P13 F14 L91	I12-F16 HydrophobicContact CG2-CE2 4.27Å; P13-F16 PolarHBondContact O-N 2.62Å; F14-F16 PolarHBondContact O-N 3.23Å; F16-L91 HydrophobicContact CE1-CD1 4.21Å; F16-L91 HydrophobicContact CE2-CD1 3.76Å; F16-L91 HydrophobicContact CZ-CD1 3.3Å
17	I	89.2	Confident	91.5	Very high	86 Å²	86	64.1 Å²	64.1	44%	0.441	31%	0.314	S	S	.	.	S	Bend	trans	-76.2	129.2	178.5	-57.3	174.6	0	0	0	109.1	F14 N19 M20	F14-I17 HydrophobicContact CD1-CD1 3.96Å; F14-I17 HydrophobicContact CE1-CD1 4.5Å; F14-I17 PolarHBondContact O-N 2.95Å; I17-N19 PolarHBondContact O-N 3.35Å; I17-M20 HydrophobicContact CB-CB 4.33Å; I17-M20 HydrophobicContact CB-CG 3.7Å; I17-M20 HydrophobicContact CG2-CG 3.51Å; I17-M20 PolarHBondContact O-N 3.39Å
18	N	79.4	Confident	91.5	Very high	121 Å²	121	61.5 Å²	61.5	65%	0.647	30%	0.303	S	S	*	.	T	Hydrogen-bonded Turn	trans	-57.1	138.1	179.4	-72.1	-17.3	0	0	0	111.4	M20	N18-M20 VanDerWaalsContact C-N 3.27Å; N18-M20 PolarHBondContact O-N 2.71Å
19	N	82.4	Confident	91.5	Very high	134 Å²	134	62.6 Å²	62.6	72%	0.717	31%	0.308	S	S	*	.	T	Hydrogen-bonded Turn	trans	68.1	7	177.9	-58.7	-18.2	0	0	0	117.2	I17 Y21	I17-N19 PolarHBondContact O-N 3.35Å; N19-Y21 VanDerWaalsContact C-N 3.31Å; N19-Y21 PolarHBondContact O-N 3.28Å
20	M	89.2	Confident	91.6	Very high	54 Å²	54	64.4 Å²	64.4	27%	0.266	31%	0.313	S	S	.	.			trans	-86.6	15.1	-177.4	-64	-62.3	-85.2	0	0	115.4	F14 I17 N18 W22 M23 V24	F14-M20 HydrophobicContact CD1-CE 4.28Å; I17-M20 HydrophobicContact CB-CB 4.33Å; I17-M20 HydrophobicContact CB-CG 3.7Å; I17-M20 HydrophobicContact CG2-CG 3.51Å; I17-M20 PolarHBondContact O-N 3.39Å; N18-M20 VanDerWaalsContact C-N 3.27Å; N18-M20 PolarHBondContact O-N 2.71Å; M20-W22 PolarHBondContact O-N 3.39Å; M20-M23 HydrophobicContact CB-CB 4.41Å; M20-M23 HydrophobicContact CE-CB 3.76Å; M20-M23 HydrophobicContact CE-CG 3.57Å; M20-M23 PolarHBondContact O-N 2.81Å; M20-M23 VanDerWaalsContact O-N 3.14Å; M20-M23 HydrophobicContact SD-CB 4.2Å; M20-V24 PolarHBondContact O-N 3.5Å; M20-V24 VanDerWaalsContact O-N 3.08Å
21	Y	91.3	Very high	91.6	Very high	6 Å²	6	57.9 Å²	57.9	2%	0.024	28%	0.284	C	S	.	.	H	α-helix	trans	-53.7	-51	-178	-177.4	-85.6	0	0	0	112.9	N19 M23 V24 Q25 L73 S76 N80 F89 L90	N19-Y21 VanDerWaalsContact C-N 3.31Å; N19-Y21 PolarHBondContact O-N 3.28Å; Y21-M23 VanDerWaalsContact C-N 3.33Å; Y21-M23 PolarHBondContact O-N 2.92Å; Y21-V24 PolarHBondContact O-N 3.41Å; Y21-Q25 PolarHBondContact O-N 3.5Å; Y21-L73 WeakPolarHBondContact CE1-O 2.92Å; Y21-L73 HydrophobicContact CE2-CD2 4.25Å; Y21-L73 PolarHBondContact OH-O 3.21Å; Y21-S76 PolarHBondContact OH-O 3.42Å; Y21-S76 PolarHBondContact OH-OG 2.92Å; Y21-N80 HydrophobicContact CD1-CB 4.28Å; Y21-N80 HydrophobicContact CD2-CB 4.16Å; Y21-N80 HydrophobicContact CE1-CB 4.39Å; Y21-N80 HydrophobicContact CE2-CB 4.26Å; Y21-N80 HydrophobicContact CG-CB 4.19Å; Y21-F89 HydrophobicContact CE2-CD1 4.37Å; Y21-L90 HydrophobicContact CD2-CD1 3.92Å; Y21-L90 HydrophobicContact CD2-CD2 3.58Å; Y21-L90 HydrophobicContact CD2-CG 3.9Å; Y21-L90 HydrophobicContact CE2-CD2 3.66Å; Y21-L90 HydrophobicContact CE2-CG 4.23Å; Y21-L90 HydrophobicContact CG-CD2 4.37Å
22	W	92.4	Very high	91.6	Very high	96 Å²	96	57.6 Å²	57.6	36%	0.364	28%	0.283	S	S	.	.	H	α-helix	trans	-71	-29.8	-179	-59.8	115.1	0	0	0	112.6	M20 Q25 I26 L74 E77	M20-W22 PolarHBondContact O-N 3.39Å; W22-Q25 VanDerWaalsContact CZ3-OE1 3.23Å; W22-Q25 WeakPolarHBondContact O-CB 3.49Å; W22-Q25 PolarHBondContact O-N 3.26Å; W22-I26 WeakPolarHBondContact O-CG1 3.2Å; W22-I26 PolarHBondContact O-N 3Å; W22-L74 HydrophobicContact CZ3-CD2 4.25Å; W22-E77 HydrophobicContact CH2-CB 4.33Å; W22-E77 HydrophobicContact CH2-CG 4.05Å; W22-E77 HydrophobicContact CZ2-CG 4.05Å
23	M	93.5	Very high	91.6	Very high	74 Å²	74	60.2 Å²	60.2	37%	0.365	29%	0.292	S	S	.	.	H	α-helix	trans	-66.6	-43.7	177.3	-173.8	61.3	159.2	0	0	111.3	M20 Y21 Q25 I26 M27	M20-M23 HydrophobicContact CB-CB 4.41Å; M20-M23 HydrophobicContact CE-CB 3.76Å; M20-M23 HydrophobicContact CE-CG 3.57Å; M20-M23 PolarHBondContact O-N 2.81Å; M20-M23 VanDerWaalsContact O-N 3.14Å; M20-M23 HydrophobicContact SD-CB 4.2Å; Y21-M23 VanDerWaalsContact C-N 3.33Å; Y21-M23 PolarHBondContact O-N 2.92Å; M23-Q25 VanDerWaalsContact C-N 3.27Å; M23-Q25 PolarHBondContact O-N 2.68Å; M23-I26 PolarHBondContact O-N 2.61Å; M23-M27 HydrophobicContact CE-CE 3.27Å; M23-M27 WeakPolarHBondContact O-CG 3.43Å; M23-M27 PolarHBondContact O-N 2.95Å; M23-M27 HydrophobicContact SD-CE 4.05Å
24	V	94.5	Very high	91.6	Very high	1 Å²	1	59.2 Å²	59.2	1%	0.006	28%	0.282	C	S	.	.	H	α-helix	trans	-56.7	-45.3	174.5	173.2	0	0	0	0	110.3	F14 M20 Y21 I26 M27 M28 L73 L90 I94	F14-V24 HydrophobicContact CB-CG2 4.24Å; M20-V24 PolarHBondContact O-N 3.5Å; M20-V24 VanDerWaalsContact O-N 3.08Å; Y21-V24 PolarHBondContact O-N 3.41Å; V24-I26 PolarHBondContact O-N 3.28Å; V24-M27 PolarHBondContact O-N 3.32Å; V24-M28 HydrophobicContact CG1-CG 4.48Å; V24-M28 WeakPolarHBondContact O-CG 3.49Å; V24-M28 PolarHBondContact O-N 3.05Å; V24-L73 HydrophobicContact CG1-CD1 4.32Å; V24-L90 HydrophobicContact CG1-CD2 4.4Å; V24-I94 HydrophobicContact CG1-CD1 3.92Å
25	Q	94.1	Very high	91.7	Very high	14 Å²	14	55 Å²	55	7%	0.065	26%	0.263	C	S	.	.	H	α-helix	trans	-62	-45	178.2	-174.8	-158.6	-59	0	0	112.9	Y21 W22 M23 M27 M28 F29 L73 L74	Y21-Q25 PolarHBondContact O-N 3.5Å; W22-Q25 VanDerWaalsContact CZ3-OE1 3.23Å; W22-Q25 WeakPolarHBondContact O-CB 3.49Å; W22-Q25 PolarHBondContact O-N 3.26Å; M23-Q25 VanDerWaalsContact C-N 3.27Å; M23-Q25 PolarHBondContact O-N 2.68Å; Q25-M27 VanDerWaalsContact C-N 3.3Å; Q25-M27 PolarHBondContact O-N 3.4Å; Q25-M28 WeakPolarHBondContact O-CB 3.44Å; Q25-M28 PolarHBondContact O-N 2.99Å; Q25-F29 HydrophobicContact CG-CD2 4.12Å; Q25-F29 HydrophobicContact CG-CE2 3.9Å; Q25-F29 WeakPolarHBondContact O-CD2 3.48Å; Q25-F29 PolarHBondContact O-N 2.96Å; Q25-F29 VanDerWaalsContact O-N 3.08Å; Q25-L73 HydrophobicContact CB-CB 4.14Å; Q25-L73 HydrophobicContact CB-CD1 3.99Å; Q25-L73 HydrophobicContact CG-CB 3.89Å; Q25-L73 HydrophobicContact CG-CD1 4.34Å; Q25-L74 VanDerWaalsContact CD-CG 3.44Å; Q25-L74 HydrophobicContact CG-CG 4.41Å
26	I	94.2	Very high	91.7	Very high	99 Å²	99	57.6 Å²	57.6	51%	0.508	28%	0.277	S	S	.	.	H	α-helix	trans	-61.4	-42.2	178.5	-69.2	164.1	0	0	0	110.3	W22 M23 V24 M28 F29 F30	W22-I26 WeakPolarHBondContact O-CG1 3.2Å; W22-I26 PolarHBondContact O-N 3Å; M23-I26 PolarHBondContact O-N 2.61Å; V24-I26 PolarHBondContact O-N 3.28Å; I26-M28 VanDerWaalsContact C-N 3.3Å; I26-M28 PolarHBondContact O-N 2.8Å; I26-F29 PolarHBondContact O-N 3.45Å; I26-F30 PolarHBondContact O-N 3.36Å
27	M	95	Very high	91.7	Very high	55 Å²	55	59.1 Å²	59.1	27%	0.271	29%	0.29	S	S	.	.	H	α-helix	trans	-62.8	-37.6	176.6	-69.9	-63	172.1	0	0	112.3	F7 L11 M23 V24 Q25 F30 I31	F7-M27 HydrophobicContact CE1-CB 4.2Å; F7-M27 HydrophobicContact CZ-CB 4.16Å; F7-M27 HydrophobicContact CZ-SD 4.08Å; L11-M27 HydrophobicContact CD1-CB 4.29Å; L11-M27 HydrophobicContact CD2-CB 3.56Å; L11-M27 HydrophobicContact CD2-CG 3.95Å; M23-M27 HydrophobicContact CE-CE 3.27Å; M23-M27 WeakPolarHBondContact O-CG 3.43Å; M23-M27 PolarHBondContact O-N 2.95Å; M23-M27 HydrophobicContact SD-CE 4.05Å; V24-M27 PolarHBondContact O-N 3.32Å; Q25-M27 VanDerWaalsContact C-N 3.3Å; Q25-M27 PolarHBondContact O-N 3.4Å; M27-F30 WeakPolarHBondContact O-CB 3.36Å; M27-F30 PolarHBondContact O-N 2.94Å; M27-I31 WeakPolarHBondContact O-CG1 3.38Å; M27-I31 PolarHBondContact O-N 3.25Å
28	M	94.1	Very high	91.5	Very high	0 Å²	0	59.2 Å²	59.2	0%	0	29%	0.289	C	S	.	.	H	α-helix	trans	-64.3	-41.3	176	-65.3	-82.3	-74.3	0	0	112	L8 L11 V24 Q25 I26 F30 I31 S32 C69 L97	L8-M28 HydrophobicContact CD2-SD 3.91Å; L11-M28 HydrophobicContact CD1-CG 4.2Å; L11-M28 HydrophobicContact CD1-SD 3.81Å; V24-M28 HydrophobicContact CG1-CG 4.48Å; V24-M28 WeakPolarHBondContact O-CG 3.49Å; V24-M28 PolarHBondContact O-N 3.05Å; Q25-M28 WeakPolarHBondContact O-CB 3.44Å; Q25-M28 PolarHBondContact O-N 2.99Å; I26-M28 VanDerWaalsContact C-N 3.3Å; I26-M28 PolarHBondContact O-N 2.8Å; M28-F30 VanDerWaalsContact C-N 3.34Å; M28-I31 PolarHBondContact O-N 3Å; M28-I31 HydrophobicContact SD-CD1 4.3Å; M28-S32 PolarHBondContact O-N 2.95Å; M28-S32 VanDerWaalsContact O-N 3.16Å; M28-C69 HydrophobicContact CE-CB 3.92Å; M28-L97 HydrophobicContact CE-CB 4.37Å; M28-L97 HydrophobicContact CE-CD2 3.17Å; M28-L97 HydrophobicContact CE-CG 4.31Å; M28-L97 HydrophobicContact SD-CD2 3.67Å
29	F	94.7	Very high	91.5	Very high	25 Å²	25	57.2 Å²	57.2	11%	0.11	28%	0.279	C	S	.	.	H	α-helix	trans	-62.1	-41.9	171	-81.5	-66.4	0	0	0	111.7	Q25 I26 I31 S32 F33 S70 L71 L74 L427	Q25-F29 HydrophobicContact CG-CD2 4.12Å; Q25-F29 HydrophobicContact CG-CE2 3.9Å; Q25-F29 WeakPolarHBondContact O-CD2 3.48Å; Q25-F29 PolarHBondContact O-N 2.96Å; Q25-F29 VanDerWaalsContact O-N 3.08Å; I26-F29 PolarHBondContact O-N 3.45Å; F29-I31 VanDerWaalsContact C-N 3.33Å; F29-I31 PolarHBondContact O-N 2.85Å; F29-S32 WeakPolarHBondContact O-CB 3.43Å; F29-S32 PolarHBondContact O-N 3.2Å; F29-S32 PolarHBondContact O-OG 3.08Å; F29-F33 HydrophobicContact CB-CE2 4.33Å; F29-F33 WeakPolarHBondContact O-CD2 3.27Å; F29-F33 PolarHBondContact O-N 2.73Å; F29-S70 WeakPolarHBondContact CD1-OG 3.06Å; F29-S70 WeakPolarHBondContact CE1-OG 3.22Å; F29-S70 WeakPolarHBondContact CZ-OG 3.4Å; F29-L71 HydrophobicContact CZ-CD2 4.26Å; F29-L74 HydrophobicContact CE2-CD1 3.71Å; F29-L74 HydrophobicContact CE2-CG 4.28Å; F29-L74 HydrophobicContact CZ-CD1 3.64Å; F29-L427 HydrophobicContact CE1-CD1 4.09Å; F29-L427 HydrophobicContact CZ-CD1 3.86Å
30	F	94.7	Very high	91.2	Very high	115 Å²	115	52 Å²	52	50%	0.504	25%	0.251	S	S	.	.	H	α-helix	trans	-58.5	-43	177.6	-173.5	-110.2	0	0	0	112.3	F7 I26 M27 M28 S32 F33 I34	F7-F30 HydrophobicContact CE2-CD1 4.39Å; F7-F30 HydrophobicContact CZ-CD1 4.37Å; I26-F30 PolarHBondContact O-N 3.36Å; M27-F30 WeakPolarHBondContact O-CB 3.36Å; M27-F30 PolarHBondContact O-N 2.94Å; M28-F30 VanDerWaalsContact C-N 3.34Å; F30-S32 VanDerWaalsContact C-N 3.33Å; F30-S32 PolarHBondContact O-N 3.05Å; F30-F33 PolarHBondContact O-N 3.16Å; F30-I34 HydrophobicContact CD1-CD1 3.53Å; F30-I34 HydrophobicContact CD1-CG1 4.43Å; F30-I34 HydrophobicContact CE1-CD1 3.29Å; F30-I34 HydrophobicContact CE1-CG1 4.21Å; F30-I34 HydrophobicContact CG-CD1 4.31Å; F30-I34 HydrophobicContact CZ-CD1 3.86Å; F30-I34 HydrophobicContact CZ-CG1 4.35Å; F30-I34 WeakPolarHBondContact O-CG1 3.4Å; F30-I34 PolarHBondContact O-N 3.27Å
31	I	94.4	Very high	90.4	Very high	4 Å²	4	52.1 Å²	52.1	2%	0.021	25%	0.25	C	C	.	.	H	α-helix	trans	-59.3	-45.4	172.9	-56.1	164.7	0	0	0	111	I4 F7 L8 L11 M27 M28 F29 F33 I34 F35 L66	I4-I31 HydrophobicContact CG2-CG2 3.99Å; F7-I31 HydrophobicContact CD1-CD1 3.1Å; F7-I31 HydrophobicContact CD1-CG1 3.17Å; F7-I31 HydrophobicContact CE1-CD1 3.25Å; F7-I31 HydrophobicContact CE1-CG1 3.09Å; F7-I31 HydrophobicContact CE2-CG1 4.46Å; F7-I31 HydrophobicContact CG-CD1 4.16Å; F7-I31 HydrophobicContact CG-CG1 3.92Å; F7-I31 HydrophobicContact CZ-CD1 4.37Å; F7-I31 HydrophobicContact CZ-CG1 3.79Å; L8-I31 HydrophobicContact CD2-CD1 3.47Å; L8-I31 VanDerWaalsContact CD2-CD1 3.47Å; L8-I31 HydrophobicContact CG-CD1 4.27Å; L11-I31 HydrophobicContact CD1-CD1 4.02Å; M27-I31 WeakPolarHBondContact O-CG1 3.38Å; M27-I31 PolarHBondContact O-N 3.25Å; M28-I31 PolarHBondContact O-N 3Å; M28-I31 HydrophobicContact SD-CD1 4.3Å; F29-I31 VanDerWaalsContact C-N 3.33Å; F29-I31 PolarHBondContact O-N 2.85Å; I31-F33 VanDerWaalsContact C-N 3.26Å; I31-F33 PolarHBondContact O-N 3.07Å; I31-I34 PolarHBondContact O-N 2.9Å; I31-I34 VanDerWaalsContact O-N 3.14Å; I31-F35 WeakPolarHBondContact O-CB 3.37Å; I31-F35 PolarHBondContact O-N 3.33Å; I31-L66 HydrophobicContact CB-CD2 4.32Å; I31-L66 HydrophobicContact CG2-CD1 4.11Å; I31-L66 HydrophobicContact CG2-CD2 3.73Å
32	S	93.6	Very high	89.8	Confident	0 Å²	0	57.5 Å²	57.5	0%	0	28%	0.277	C	S	.	.	H	α-helix	trans	-60.3	-38.9	-178.1	74.8	0	0	0	0	111.6	M28 F29 F30 F35 L36	M28-S32 PolarHBondContact O-N 2.95Å; M28-S32 VanDerWaalsContact O-N 3.16Å; F29-S32 WeakPolarHBondContact O-CB 3.43Å; F29-S32 PolarHBondContact O-N 3.2Å; F29-S32 PolarHBondContact O-OG 3.08Å; F30-S32 VanDerWaalsContact C-N 3.33Å; F30-S32 PolarHBondContact O-N 3.05Å; S32-F35 PolarHBondContact O-N 3.03Å; S32-L36 WeakPolarHBondContact O-CG 3.4Å; S32-L36 PolarHBondContact O-N 3.11Å
33	F	93.4	Very high	89.3	Confident	103 Å²	103	56 Å²	56	45%	0.452	28%	0.276	S	S	.	.	H	α-helix	trans	-70.1	-39.3	174.2	-70.2	-63.3	0	0	0	112.6	F29 F30 I31 F35 L36 L37 W67	F29-F33 HydrophobicContact CB-CE2 4.33Å; F29-F33 WeakPolarHBondContact O-CD2 3.27Å; F29-F33 PolarHBondContact O-N 2.73Å; F30-F33 PolarHBondContact O-N 3.16Å; I31-F33 VanDerWaalsContact C-N 3.26Å; I31-F33 PolarHBondContact O-N 3.07Å; F33-F35 VanDerWaalsContact C-N 3.29Å; F33-F35 PolarHBondContact O-N 2.94Å; F33-L36 HydrophobicContact CD1-CD1 4.02Å; F33-L36 HydrophobicContact CE1-CD1 4.46Å; F33-L36 WeakPolarHBondContact O-CB 3.42Å; F33-L36 PolarHBondContact O-N 3.26Å; F33-L37 VanDerWaalsContact O-CG 3.31Å; F33-L37 WeakPolarHBondContact O-CG 3.26Å; F33-L37 PolarHBondContact O-N 2.77Å; F33-W67 HydrophobicContact CE1-CZ3 4.28Å; F33-W67 HydrophobicContact CZ-CH2 4.4Å; F33-W67 HydrophobicContact CZ-CZ3 4.19Å
34	I	92.8	Very high	88.8	Confident	56 Å²	56	61.1 Å²	61.1	29%	0.287	29%	0.292	S	S	.	.	H	α-helix	trans	-59.8	-43.4	172.5	-67.7	163.6	0	0	0	110.5	F30 I31 L37 M38	F30-I34 HydrophobicContact CD1-CD1 3.53Å; F30-I34 HydrophobicContact CD1-CG1 4.43Å; F30-I34 HydrophobicContact CE1-CD1 3.29Å; F30-I34 HydrophobicContact CE1-CG1 4.21Å; F30-I34 HydrophobicContact CG-CD1 4.31Å; F30-I34 HydrophobicContact CZ-CD1 3.86Å; F30-I34 HydrophobicContact CZ-CG1 4.35Å; F30-I34 WeakPolarHBondContact O-CG1 3.4Å; F30-I34 PolarHBondContact O-N 3.27Å; I31-I34 PolarHBondContact O-N 2.9Å; I31-I34 VanDerWaalsContact O-N 3.14Å; I34-L37 WeakPolarHBondContact O-CB 3.34Å; I34-L37 PolarHBondContact O-N 3.18Å; I34-L37 VanDerWaalsContact O-N 3.14Å; I34-M38 HydrophobicContact CG2-CE 3.95Å; I34-M38 WeakPolarHBondContact O-CG 3.01Å; I34-M38 PolarHBondContact O-N 3.45Å; I34-M38 VanDerWaalsContact O-N 3.12Å
35	F	92.4	Very high	88.2	Confident	2 Å²	2	62.1 Å²	62.1	1%	0.009	30%	0.296	C	S	.	.	H	α-helix	trans	-67.4	-37.9	-180	-168.5	-112.1	0	0	0	112.5	M1 I4 I31 S32 F33 L37 M38 Y59 I62 L63 L66	M1-F35 HydrophobicContact SD-CE2 4.3Å; I4-F35 HydrophobicContact CD1-CD2 3.26Å; I4-F35 HydrophobicContact CD1-CE2 3.53Å; I4-F35 HydrophobicContact CD1-CG 4.28Å; I4-F35 HydrophobicContact CG1-CD2 4.47Å; I31-F35 WeakPolarHBondContact O-CB 3.37Å; I31-F35 PolarHBondContact O-N 3.33Å; S32-F35 PolarHBondContact O-N 3.03Å; F33-F35 VanDerWaalsContact C-N 3.29Å; F33-F35 PolarHBondContact O-N 2.94Å; F35-L37 VanDerWaalsContact C-N 3.3Å; F35-L37 PolarHBondContact O-N 3.19Å; F35-M38 PolarHBondContact O-N 3.04Å; F35-Y59 HydrophobicContact CD1-CD2 4.26Å; F35-Y59 AromaticContact CD1-CE2 3.84Å; F35-Y59 HydrophobicContact CD1-CE2 3.84Å; F35-Y59 AromaticContact CE1-CD2 3.39Å; F35-Y59 HydrophobicContact CE1-CD2 3.39Å; F35-Y59 AromaticContact CE1-CE2 3.45Å; F35-Y59 HydrophobicContact CE1-CE2 3.45Å; F35-Y59 VanDerWaalsContact CE1-CE2 3.45Å; F35-Y59 HydrophobicContact CE1-CG 4.12Å; F35-Y59 WeakPolarHBondContact CE1-O 3.25Å; F35-Y59 HydrophobicContact CE2-CD2 4.09Å; F35-Y59 HydrophobicContact CE2-CE2 4.21Å; F35-Y59 HydrophobicContact CG-CE2 4.38Å; F35-Y59 AromaticContact CZ-CD2 3.31Å; F35-Y59 HydrophobicContact CZ-CD2 3.31Å; F35-Y59 AromaticContact CZ-CE2 3.68Å; F35-Y59 HydrophobicContact CZ-CE2 3.68Å; F35-Y59 HydrophobicContact CZ-CG 4.22Å; F35-Y59 WeakPolarHBondContact O-CE2 3.48Å; F35-Y59 PolarHBondContact O-OH 3.34Å; F35-Y59 VanDerWaalsContact O-OH 3.14Å; F35-I62 HydrophobicContact CD1-CG2 4.22Å; F35-I62 HydrophobicContact CE1-CB 3.88Å; F35-I62 HydrophobicContact CE1-CG2 3.61Å; F35-I62 HydrophobicContact CE2-CG2 4.08Å; F35-I62 HydrophobicContact CZ-CB 3.85Å; F35-I62 HydrophobicContact CZ-CD1 4.47Å; F35-I62 HydrophobicContact CZ-CG2 3.5Å; F35-L63 HydrophobicContact CD1-CB 3.95Å; F35-L63 HydrophobicContact CD1-CD1 4.08Å; F35-L63 HydrophobicContact CE1-CB 3.95Å; F35-L66 HydrophobicContact CB-CD1 3.86Å; F35-L66 HydrophobicContact CD1-CD1 4.04Å; F35-L66 HydrophobicContact CG-CD1 3.95Å
36	L	90.8	Very high	87.8	Confident	56 Å²	56	62.5 Å²	62.5	29%	0.293	30%	0.3	S	S	.	.	H	α-helix	trans	-56.8	-44.3	168.3	-77.8	167.7	0	0	0	111.3	S32 F33 M38 N39 Y59 L63	S32-L36 WeakPolarHBondContact O-CG 3.4Å; S32-L36 PolarHBondContact O-N 3.11Å; F33-L36 HydrophobicContact CD1-CD1 4.02Å; F33-L36 HydrophobicContact CE1-CD1 4.46Å; F33-L36 WeakPolarHBondContact O-CB 3.42Å; F33-L36 PolarHBondContact O-N 3.26Å; L36-M38 VanDerWaalsContact C-N 3.32Å; L36-M38 PolarHBondContact O-N 2.94Å; L36-N39 PolarHBondContact O-N 3.23Å; L36-N39 PolarHBondContact O-ND2 2.94Å; L36-N39 PolarHBondContact O-OD1 2.89Å; L36-Y59 WeakPolarHBondContact CA-OH 3.22Å; L36-Y59 PolarHBondContact O-OH 3.44Å; L36-L63 HydrophobicContact CD1-CD1 4.25Å; L36-L63 HydrophobicContact CD2-CD1 3.51Å; L36-L63 HydrophobicContact CD2-CD2 3.49Å; L36-L63 VanDerWaalsContact CD2-CD2 3.49Å; L36-L63 HydrophobicContact CD2-CG 4.13Å; L36-L63 HydrophobicContact CG-CD1 3.49Å; L36-L63 VanDerWaalsContact CG-CD1 3.49Å; L36-L63 HydrophobicContact CG-CD2 4.43Å
37	L	89.3	Confident	87.3	Confident	140 Å²	140	61.1 Å²	61.1	73%	0.733	29%	0.292	S	S	*	.	H	α-helix	trans	-66.9	-29.2	-179.5	-68.9	170.4	0	0	0	113.6	F33 I34 F35 N39	F33-L37 VanDerWaalsContact O-CG 3.31Å; F33-L37 WeakPolarHBondContact O-CG 3.26Å; F33-L37 PolarHBondContact O-N 2.77Å; I34-L37 WeakPolarHBondContact O-CB 3.34Å; I34-L37 PolarHBondContact O-N 3.18Å; I34-L37 VanDerWaalsContact O-N 3.14Å; F35-L37 VanDerWaalsContact C-N 3.3Å; F35-L37 PolarHBondContact O-N 3.19Å; L37-N39 VanDerWaalsContact C-N 3.26Å; L37-N39 PolarHBondContact O-N 3.01Å
38	M	85.7	Confident	86.8	Confident	89 Å²	89	63.6 Å²	63.6	44%	0.438	31%	0.305	S	S	.	.	H	α-helix	trans	-67.4	-23.1	178.7	-65.7	-65.9	168.5	0	0	113.4	I34 F35 L36 N40	I34-M38 HydrophobicContact CG2-CE 3.95Å; I34-M38 WeakPolarHBondContact O-CG 3.01Å; I34-M38 PolarHBondContact O-N 3.45Å; I34-M38 VanDerWaalsContact O-N 3.12Å; F35-M38 PolarHBondContact O-N 3.04Å; L36-M38 VanDerWaalsContact C-N 3.32Å; L36-M38 PolarHBondContact O-N 2.94Å; M38-N40 PolarHBondContact O-N 3.47Å; M38-N40 PolarHBondContact O-OD1 3.33Å
39	N	78.9	Confident	86.3	Confident	79 Å²	79	64.8 Å²	64.8	42%	0.422	31%	0.313	S	S	.	.			trans	38.2	62.5	170.5	-79.7	-35.5	0	0	0	115.9	L36 L37 F41	L36-N39 PolarHBondContact O-N 3.23Å; L36-N39 PolarHBondContact O-ND2 2.94Å; L36-N39 PolarHBondContact O-OD1 2.89Å; L37-N39 VanDerWaalsContact C-N 3.26Å; L37-N39 PolarHBondContact O-N 3.01Å; N39-F41 VanDerWaalsContact C-N 3.29Å; N39-F41 HydrophobicContact CB-CD2 4.06Å; N39-F41 HydrophobicContact CB-CE2 3.87Å; N39-F41 PolarHBondContact O-N 2.89Å; N39-F41 WeakPolarHBondContact OD1-CE2 3.46Å
40	N	75.1	Confident	86	Confident	24 Å²	24	73.6 Å²	73.6	13%	0.128	35%	0.347	C	S	.	.			trans	-83.5	66.8	176.3	-69.2	-28.3	0	0	0	112.3	M38 M42 S46 E47 Y59	M38-N40 PolarHBondContact O-N 3.47Å; M38-N40 PolarHBondContact O-OD1 3.33Å; N40-M42 PolarHBondContact O-N 3.47Å; N40-M42 VanDerWaalsContact O-N 3.09Å; N40-S46 WeakPolarHBondContact CB-OG 3.27Å; N40-E47 PolarHBondContact ND2-OE1 3.19Å; N40-Y59 HydrophobicContact CB-CD2 4.21Å
41	F	73.8	Confident	85.8	Confident	57 Å²	57	71.4 Å²	71.4	25%	0.25	34%	0.338	C	S	.	.			trans	-85	50.7	175.4	-59.9	-63	0	0	0	112.3	N39 M56 Y59 K438 S441	N39-F41 VanDerWaalsContact C-N 3.29Å; N39-F41 HydrophobicContact CB-CD2 4.06Å; N39-F41 HydrophobicContact CB-CE2 3.87Å; N39-F41 PolarHBondContact O-N 2.89Å; N39-F41 WeakPolarHBondContact OD1-CE2 3.46Å; F41-M56 HydrophobicContact CB-CE 4.31Å; F41-M56 HydrophobicContact CD1-CE 4.27Å; F41-Y59 HydrophobicContact CD1-CD1 4.43Å; F41-Y59 HydrophobicContact CD1-CE1 4.4Å; F41-Y59 AromaticContact CE1-CD1 3.97Å; F41-Y59 HydrophobicContact CE1-CD1 3.97Å; F41-Y59 AromaticContact CE1-CE1 3.62Å; F41-Y59 HydrophobicContact CE1-CE1 3.62Å; F41-Y59 AromaticContact CZ-CE1 3.86Å; F41-Y59 HydrophobicContact CZ-CE1 3.86Å; F41-K438 VanDerWaalsContact CE2-NZ 3.27Å; F41-S441 VanDerWaalsContact CD1-CB 3.42Å
42	M	79	Confident	85.7	Confident	119 Å²	119	71.3 Å²	71.3	59%	0.586	34%	0.337	S	S	*	.			trans	-104.9	137.9	173.6	-63.4	-62.6	-173.6	0	0	109.8	N40 Y44 M56	N40-M42 PolarHBondContact O-N 3.47Å; N40-M42 VanDerWaalsContact O-N 3.09Å; M42-Y44 PolarHBondContact O-N 3.05Å; M42-M56 PolarHBondContact O-N 2.99Å; M42-M56 VanDerWaalsContact O-N 3.14Å
43	N	81.7	Confident	85.6	Confident	64 Å²	64	71.3 Å²	71.3	34%	0.342	34%	0.337	S	S	.	.	S	Bend	trans	-69.3	-25.4	177.8	-64.6	19.7	0	0	0	111.5	L444 L446	N43-L444 PolarHBondContact ND2-O 3.17Å; N43-L444 VanDerWaalsContact ND2-O 3.15Å; N43-L444 PolarHBondContact OD1-O 3.38Å; N43-L446 PolarHBondContact ND2-O 3.31Å
44	Y	81.9	Confident	85.4	Confident	182 Å²	182	66.4 Å²	66.4	71%	0.714	32%	0.316	S	S	*	.	S	Bend	trans	-89.9	154	173.1	-45.3	-72.6	0	0	0	110.1	M42 S46	M42-Y44 PolarHBondContact O-N 3.05Å; Y44-S46 PolarHBondContact O-N 2.88Å
45	W	82.5	Confident	85.3	Confident	21 Å²	21	64.1 Å²	64.1	8%	0.08	30%	0.304	C	S	.	.			trans	-68.1	130.3	176.3	-46.9	48.1	0	0	0	111.1	D55 S106 M107 F170 Y171	W45-D55 HydrophobicContact CB-CB 4.44Å; W45-D55 HydrophobicContact CD2-CB 4.27Å; W45-D55 HydrophobicContact CG-CB 4.03Å; W45-S106 WeakPolarHBondContact CH2-O 3.42Å; W45-M107 HydrophobicContact CB-CE 3.39Å; W45-M107 HydrophobicContact CB-SD 4.33Å; W45-M107 HydrophobicContact CD2-CE 3.42Å; W45-M107 VanDerWaalsContact CD2-CE 3.42Å; W45-M107 HydrophobicContact CD2-SD 3.24Å; W45-M107 VanDerWaalsContact CE2-SD 3.58Å; W45-M107 HydrophobicContact CE3-CE 3.29Å; W45-M107 HydrophobicContact CE3-CG 4.29Å; W45-M107 HydrophobicContact CE3-SD 3.21Å; W45-M107 HydrophobicContact CG-CE 3.59Å; W45-M107 HydrophobicContact CG-SD 3.85Å; W45-M107 HydrophobicContact CH2-SD 3.76Å; W45-M107 HydrophobicContact CZ2-SD 3.82Å; W45-M107 HydrophobicContact CZ3-CE 4.06Å; W45-M107 HydrophobicContact CZ3-CG 4.15Å; W45-M107 HydrophobicContact CZ3-SD 3.48Å; W45-M107 WeakPolarHBondContact CZ3-SD 3.48Å; W45-F170 HydrophobicContact CH2-CD2 4.15Å; W45-F170 HydrophobicContact CZ2-CB 4.28Å; W45-F170 HydrophobicContact CZ2-CD2 4.1Å; W45-Y171 WeakPolarHBondContact CA-OH 3.49Å; W45-Y171 HydrophobicContact CB-CE2 3.69Å; W45-Y171 WeakPolarHBondContact CB-OH 3.44Å; W45-Y171 AromaticContact CD1-CE1 3.3Å; W45-Y171 AromaticContact CD1-CE2 3.18Å; W45-Y171 AromaticContact CD1-CZ 2.8Å; W45-Y171 AromaticContact CD2-CE2 3.9Å; W45-Y171 HydrophobicContact CD2-CE2 3.9Å; W45-Y171 AromaticContact CE2-CE2 3.96Å; W45-Y171 HydrophobicContact CG-CD2 4.36Å; W45-Y171 HydrophobicContact CG-CE1 4.15Å; W45-Y171 AromaticContact CG-CE2 3.27Å; W45-Y171 HydrophobicContact CG-CE2 3.27Å; W45-Y171 AromaticContact CG-CZ 3.22Å; W45-Y171 PolarHBondContact N-OH 3.32Å; W45-Y171 AromaticContact NE1-CD2 3.95Å; W45-Y171 AromaticContact NE1-CE1 3.72Å; W45-Y171 AromaticContact NE1-CE2 3.49Å; W45-Y171 AromaticContact NE1-CZ 3.47Å
46	S	85.9	Confident	85.2	Confident	23 Å²	23	64.5 Å²	64.5	16%	0.161	31%	0.306	C	S	.	.	E	Extended strand (participates in β ladder)	trans	-109.6	171.3	178.9	67.9	0	0	0	0	110.1	N40 Y44 I48 C54	N40-S46 WeakPolarHBondContact CB-OG 3.27Å; Y44-S46 PolarHBondContact O-N 2.88Å; S46-I48 VanDerWaalsContact C-N 3.29Å; S46-I48 PolarHBondContact O-N 3.39Å; S46-C54 PolarHBondContact N-O 2.66Å; S46-C54 PolarHBondContact O-N 2.82Å; S46-C54 PolarHBondContact OG-O 3.29Å
47	E	82.7	Confident	85.3	Confident	69 Å²	69	62.5 Å²	62.5	32%	0.322	30%	0.296	S	S	.	.	E	Extended strand (participates in β ladder)	trans	51.8	40.9	176.4	-58.5	-169.5	-178.8	0	0	115.3	M1 N40 S49	M1-E47 PolarHBondContact N-OE2 3.49Å; N40-E47 PolarHBondContact ND2-OE1 3.19Å; E47-S49 PolarHBondContact O-N 3.37Å
48	I	85.5	Confident	85.5	Confident	107 Å²	107	55.9 Å²	55.9	55%	0.549	26%	0.261	S	S	.	.	E	Extended strand (participates in β ladder)	trans	-67.5	124.8	-176.6	-52.7	178.2	0	0	0	109.9	S46 L52 M107	S46-I48 VanDerWaalsContact C-N 3.29Å; S46-I48 PolarHBondContact O-N 3.39Å; I48-L52 WeakPolarHBondContact CA-O 3.48Å; I48-M107 HydrophobicContact CD1-CE 4.09Å; I48-M107 HydrophobicContact CG1-CE 3.78Å; I48-M107 HydrophobicContact CG2-CE 4.36Å
49	S	84.2	Confident	85.9	Confident	26 Å²	26	51.9 Å²	51.9	18%	0.182	24%	0.241	C	C	.	.	E	Extended strand (participates in β ladder)	trans	-146.6	125.8	170.3	61.8	0	0	0	0	109.8	L2 E47 F51 L52	L2-S49 WeakPolarHBondContact CG-OG 3.16Å; E47-S49 PolarHBondContact O-N 3.37Å; S49-F51 PolarHBondContact O-N 3.11Å; S49-F51 VanDerWaalsContact O-N 3.16Å; S49-L52 PolarHBondContact N-O 3.12Å; S49-L52 WeakPolarHBondContact O-CB 3.49Å; S49-L52 PolarHBondContact O-N 3.48Å
50	Y	87.3	Confident	86.5	Confident	209 Å²	209	48.3 Å²	48.3	82%	0.82	22%	0.222	S	C	*	.	T	Hydrogen-bonded Turn	trans	51.5	-114.3	-173	-57.5	-77.3	0	0	0	112.1	L2	L2-Y50 HydrophobicContact CD1-CD2 4.23Å; L2-Y50 HydrophobicContact CD1-CE2 4.1Å
51	F	90.7	Very high	87.5	Confident	69 Å²	69	47.2 Å²	47.2	30%	0.303	22%	0.217	S	C	.	.	T	Hydrogen-bonded Turn	trans	-98	3.1	178.1	61.5	-92.1	0	0	0	113.3	S49 L102 M107 M111 F115	S49-F51 PolarHBondContact O-N 3.11Å; S49-F51 VanDerWaalsContact O-N 3.16Å; F51-L102 HydrophobicContact CE2-CD2 4.35Å; F51-M107 VanDerWaalsContact O-CB 3.31Å; F51-M107 WeakPolarHBondContact O-CB 3.33Å; F51-M107 WeakPolarHBondContact O-CG 3.45Å; F51-M107 PolarHBondContact O-N 3.48Å; F51-M111 HydrophobicContact CE2-CE 4.3Å; F51-M111 HydrophobicContact CZ-CE 4.32Å; F51-F115 HydrophobicContact CD2-CE2 4.47Å; F51-F115 AromaticContact CE2-CE2 3.72Å; F51-F115 HydrophobicContact CE2-CE2 3.72Å; F51-F115 HydrophobicContact CE2-CZ 4.11Å; F51-F115 HydrophobicContact CZ-CE2 4.37Å; F51-F115 HydrophobicContact CZ-CZ 4.31Å
52	L	92.1	Very high	88.6	Confident	3 Å²	3	44.5 Å²	44.5	2%	0.016	21%	0.205	C	C	.	.	E	Extended strand (participates in β ladder)	trans	-102.4	143.1	-174.2	-56.9	165.6	0	0	0	110.5	M1 L2 I5 I48 S49 L102 S105	M1-L52 HydrophobicContact CB-CB 4.21Å; M1-L52 HydrophobicContact CB-CD1 4.46Å; L2-L52 HydrophobicContact CD2-CD1 4.13Å; I5-L52 HydrophobicContact CD1-CD1 3.33Å; I5-L52 HydrophobicContact CD1-CD2 4.32Å; I5-L52 HydrophobicContact CD1-CG 4.48Å; I48-L52 WeakPolarHBondContact CA-O 3.48Å; S49-L52 PolarHBondContact N-O 3.12Å; S49-L52 WeakPolarHBondContact O-CB 3.49Å; S49-L52 PolarHBondContact O-N 3.48Å; L52-L102 HydrophobicContact CD2-CD2 3.81Å; L52-S105 CarbonylContact C-O 3.59Å; L52-S105 VanDerWaalsContact CA-O 3.3Å; L52-S105 WeakPolarHBondContact CA-O 3.41Å; L52-S105 WeakPolarHBondContact CD2-OG 2.96Å
53	G	91.5	Very high	89.3	Confident	0 Å²	0	40 Å²	40	0%	0	18%	0.183	C	C	.	.	E	Extended strand (participates in β ladder)	trans	-163	177.2	159.8	0	0	0	0	0	111.7	S105	G53-S105 PolarHBondContact N-O 3.48Å; G53-S105 CarbonylContact O-C 3.59Å; G53-S105 VanDerWaalsContact O-CA 3.28Å; G53-S105 WeakPolarHBondContact O-CA 3.27Å; G53-S105 WeakPolarHBondContact O-CB 3.48Å; G53-S105 VanDerWaalsContact O-O 3.09Å
54	C	90.6	Very high	90	Very high	0 Å²	0	37.3 Å²	37.3	0%	0	17%	0.168	C	C	.	.	E	Extended strand (participates in β ladder)	trans	-137	118.8	179.4	-74.1	0	0	0	0	112.6	M1 S46 S58 I62	M1-C54 VanDerWaalsContact CE-SG 3.54Å; M1-C54 VanDerWaalsContact CG-SG 3.5Å; M1-C54 HydrophobicContact SD-CB 4.44Å; M1-C54 PolarHBondContact SD-SG 2.94Å; S46-C54 PolarHBondContact N-O 2.66Å; S46-C54 PolarHBondContact O-N 2.82Å; S46-C54 PolarHBondContact OG-O 3.29Å; C54-S58 VanDerWaalsContact CA-OG 3.28Å; C54-S58 WeakPolarHBondContact CA-OG 3.17Å; C54-I62 WeakPolarHBondContact SG-CD1 3.31Å
55	D	90.1	Very high	90.7	Very high	8 Å²	8	28.6 Å²	28.6	4%	0.043	13%	0.134	C	C	.	.			trans	-95.1	175.6	160.2	60.4	-6.3	0	0	0	111	W45 L57 S58 Y59 R233	W45-D55 HydrophobicContact CB-CB 4.44Å; W45-D55 HydrophobicContact CD2-CB 4.27Å; W45-D55 HydrophobicContact CG-CB 4.03Å; D55-L57 PolarHBondContact O-N 2.68Å; D55-L57 VanDerWaalsContact OD1-CB 3.31Å; D55-L57 WeakPolarHBondContact OD1-CB 3.42Å; D55-L57 WeakPolarHBondContact OD2-CB 3.23Å; D55-S58 PolarHBondContact N-OG 3.02Å; D55-S58 PolarHBondContact O-N 3.35Å; D55-S58 PolarHBondContact O-OG 2.79Å; D55-S58 VanDerWaalsContact OD1-CB 3.24Å; D55-S58 WeakPolarHBondContact OD1-CB 3.35Å; D55-S58 PolarHBondContact OD1-N 3.31Å; D55-S58 PolarHBondContact OD1-OG 3.46Å; D55-Y59 VanDerWaalsContact O-CB 3.29Å; D55-Y59 WeakPolarHBondContact O-CB 3.25Å; D55-Y59 PolarHBondContact O-N 3.17Å; D55-R233 IonicContact OD1-CZ 3.64Å; D55-R233 IonicContact OD1-NH2 3.88Å; D55-R233 PolarHBondContact OD1-NH2 3.46Å; D55-R233 IonicContact OD2-CZ 3.48Å; D55-R233 IonicContact OD2-NH1 3.06Å; D55-R233 PolarHBondContact OD2-NH1 3.35Å; D55-R233 IonicContact OD2-NH2 2.84Å; D55-R233 PolarHBondContact OD2-NH2 2.98Å
56	M	90.9	Very high	91.4	Very high	9 Å²	9	27.7 Å²	27.7	4%	0.044	13%	0.131	C	C	.	.	H	α-helix	trans	-52	-42.2	177.3	-178.6	-174.1	-100	0	0	112.4	F41 M42 Y59 G60 Y301 S441 W445	F41-M56 HydrophobicContact CB-CE 4.31Å; F41-M56 HydrophobicContact CD1-CE 4.27Å; M42-M56 PolarHBondContact O-N 2.99Å; M42-M56 VanDerWaalsContact O-N 3.14Å; M56-Y59 WeakPolarHBondContact O-CB 3.33Å; M56-Y59 PolarHBondContact O-N 2.95Å; M56-G60 PolarHBondContact O-N 3Å; M56-G60 VanDerWaalsContact O-N 3.11Å; M56-Y301 PolarHBondContact O-OH 3.46Å; M56-S441 VanDerWaalsContact CE-CA 3.44Å; M56-S441 VanDerWaalsContact CE-O 3.27Å; M56-S441 WeakPolarHBondContact CE-O 3.19Å; M56-S441 WeakPolarHBondContact CG-O 3.31Å; M56-W445 HydrophobicContact CB-CB 4.48Å; M56-W445 HydrophobicContact CG-CB 4.24Å; M56-W445 WeakPolarHBondContact SD-CA 3.5Å; M56-W445 HydrophobicContact SD-CB 3.51Å; M56-W445 VanDerWaalsContact SD-CB 3.51Å
57	L	92.5	Very high	91.9	Very high	15 Å²	15	27.8 Å²	27.8	8%	0.079	13%	0.128	C	C	.	.	H	α-helix	trans	-49.6	-62.4	176.1	-119	174.9	0	0	0	112.7	D55 Y229 L232 Y301 W445	D55-L57 PolarHBondContact O-N 2.68Å; D55-L57 VanDerWaalsContact OD1-CB 3.31Å; D55-L57 WeakPolarHBondContact OD1-CB 3.42Å; D55-L57 WeakPolarHBondContact OD2-CB 3.23Å; L57-Y229 HydrophobicContact CD2-CD2 4.18Å; L57-Y229 HydrophobicContact CD2-CE2 4.39Å; L57-L232 HydrophobicContact CD2-CD1 4.2Å; L57-Y301 HydrophobicContact CD2-CD2 4.17Å; L57-Y301 HydrophobicContact CD2-CE2 4.06Å; L57-Y301 WeakPolarHBondContact O-CE2 3.31Å; L57-Y301 PolarHBondContact O-OH 3.37Å; L57-W445 HydrophobicContact CB-CE3 4.3Å; L57-W445 HydrophobicContact CD1-CE3 4.03Å; L57-W445 HydrophobicContact CD1-CH2 4.49Å; L57-W445 HydrophobicContact CD1-CZ3 4Å; L57-W445 HydrophobicContact CD2-CE3 3.35Å; L57-W445 HydrophobicContact CD2-CH2 3.88Å; L57-W445 HydrophobicContact CD2-CZ3 2.94Å; L57-W445 HydrophobicContact CG-CD2 4.05Å; L57-W445 HydrophobicContact CG-CE3 3.2Å; L57-W445 HydrophobicContact CG-CH2 4.27Å; L57-W445 HydrophobicContact CG-CZ3 3.34Å
58	S	93.1	Very high	92.6	Very high	0 Å²	0	24.5 Å²	24.5	0%	0	11%	0.113	C	C	.	.	H	α-helix	trans	-68.5	-34.9	179.6	53.7	0	0	0	0	111.7	C54 D55 G60 L61 I62 F104	C54-S58 VanDerWaalsContact CA-OG 3.28Å; C54-S58 WeakPolarHBondContact CA-OG 3.17Å; D55-S58 PolarHBondContact N-OG 3.02Å; D55-S58 PolarHBondContact O-N 3.35Å; D55-S58 PolarHBondContact O-OG 2.79Å; D55-S58 VanDerWaalsContact OD1-CB 3.24Å; D55-S58 WeakPolarHBondContact OD1-CB 3.35Å; D55-S58 PolarHBondContact OD1-N 3.31Å; D55-S58 PolarHBondContact OD1-OG 3.46Å; S58-G60 PolarHBondContact O-N 3.26Å; S58-L61 PolarHBondContact O-N 3.03Å; S58-I62 WeakPolarHBondContact O-CB 3.44Å; S58-I62 WeakPolarHBondContact O-CD1 2.96Å; S58-I62 WeakPolarHBondContact O-CG1 3.43Å; S58-I62 PolarHBondContact O-N 3.36Å; S58-F104 WeakPolarHBondContact CB-O 3.37Å
59	Y	92.9	Very high	93.1	Very high	6 Å²	6	19.4 Å²	19.4	2%	0.024	9%	0.086	C	C	.	.	H	α-helix	trans	-55.1	-53.1	176.6	177	-96.1	0	0	0	111.6	F35 L36 N40 F41 D55 M56 L61 I62 L63	F35-Y59 HydrophobicContact CD1-CD2 4.26Å; F35-Y59 AromaticContact CD1-CE2 3.84Å; F35-Y59 HydrophobicContact CD1-CE2 3.84Å; F35-Y59 AromaticContact CE1-CD2 3.39Å; F35-Y59 HydrophobicContact CE1-CD2 3.39Å; F35-Y59 AromaticContact CE1-CE2 3.45Å; F35-Y59 HydrophobicContact CE1-CE2 3.45Å; F35-Y59 VanDerWaalsContact CE1-CE2 3.45Å; F35-Y59 HydrophobicContact CE1-CG 4.12Å; F35-Y59 WeakPolarHBondContact CE1-O 3.25Å; F35-Y59 HydrophobicContact CE2-CD2 4.09Å; F35-Y59 HydrophobicContact CE2-CE2 4.21Å; F35-Y59 HydrophobicContact CG-CE2 4.38Å; F35-Y59 AromaticContact CZ-CD2 3.31Å; F35-Y59 HydrophobicContact CZ-CD2 3.31Å; F35-Y59 AromaticContact CZ-CE2 3.68Å; F35-Y59 HydrophobicContact CZ-CE2 3.68Å; F35-Y59 HydrophobicContact CZ-CG 4.22Å; F35-Y59 WeakPolarHBondContact O-CE2 3.48Å; F35-Y59 PolarHBondContact O-OH 3.34Å; F35-Y59 VanDerWaalsContact O-OH 3.14Å; L36-Y59 WeakPolarHBondContact CA-OH 3.22Å; L36-Y59 PolarHBondContact O-OH 3.44Å; N40-Y59 HydrophobicContact CB-CD2 4.21Å; F41-Y59 HydrophobicContact CD1-CD1 4.43Å; F41-Y59 HydrophobicContact CD1-CE1 4.4Å; F41-Y59 AromaticContact CE1-CD1 3.97Å; F41-Y59 HydrophobicContact CE1-CD1 3.97Å; F41-Y59 AromaticContact CE1-CE1 3.62Å; F41-Y59 HydrophobicContact CE1-CE1 3.62Å; F41-Y59 AromaticContact CZ-CE1 3.86Å; F41-Y59 HydrophobicContact CZ-CE1 3.86Å; D55-Y59 VanDerWaalsContact O-CB 3.29Å; D55-Y59 WeakPolarHBondContact O-CB 3.25Å; D55-Y59 PolarHBondContact O-N 3.17Å; M56-Y59 WeakPolarHBondContact O-CB 3.33Å; M56-Y59 PolarHBondContact O-N 2.95Å; Y59-L61 VanDerWaalsContact C-N 3.32Å; Y59-L61 PolarHBondContact O-N 3.48Å; Y59-I62 PolarHBondContact O-N 3.48Å; Y59-L63 HydrophobicContact CE1-CD2 4.5Å; Y59-L63 WeakPolarHBondContact O-CB 3.33Å; Y59-L63 PolarHBondContact O-N 2.99Å
60	G	93.4	Very high	93.7	Very high	3 Å²	3	18.2 Å²	18.2	3%	0.031	8%	0.078	C	C	.	.	H	α-helix	trans	-63.2	-35.5	-179.2	0	0	0	0	0	113.7	M56 S58 L64 Y301	M56-G60 PolarHBondContact O-N 3Å; M56-G60 VanDerWaalsContact O-N 3.11Å; S58-G60 PolarHBondContact O-N 3.26Å; G60-L64 WeakPolarHBondContact O-CB 3.49Å; G60-L64 PolarHBondContact O-N 3.43Å; G60-Y301 VanDerWaalsContact CA-OH 3.25Å; G60-Y301 WeakPolarHBondContact CA-OH 3.48Å; G60-Y301 PolarHBondContact N-OH 2.77Å
61	L	95.2	Very high	94.1	Very high	2 Å²	2	8.2 Å²	8.2	1%	0.01	4%	0.039	C	C	.	.	H	α-helix	trans	-77.1	-35.5	178.6	-65.4	174.1	0	0	0	112.9	S58 Y59 L64 S65 F104 K225 Y229 Y301	S58-L61 PolarHBondContact O-N 3.03Å; Y59-L61 VanDerWaalsContact C-N 3.32Å; Y59-L61 PolarHBondContact O-N 3.48Å; L61-L64 PolarHBondContact O-N 3.18Å; L61-S65 WeakPolarHBondContact O-CB 3.32Å; L61-S65 PolarHBondContact O-N 2.84Å; L61-F104 HydrophobicContact CB-CD1 3.76Å; L61-F104 HydrophobicContact CB-CD2 4.1Å; L61-F104 HydrophobicContact CB-CE1 3.76Å; L61-F104 HydrophobicContact CB-CE2 4.1Å; L61-F104 HydrophobicContact CB-CG 3.94Å; L61-F104 HydrophobicContact CB-CZ 3.94Å; L61-F104 HydrophobicContact CD1-CD1 3.78Å; L61-F104 HydrophobicContact CD1-CE1 3.56Å; L61-F104 HydrophobicContact CD1-CZ 4.36Å; L61-F104 HydrophobicContact CG-CD1 4.42Å; L61-F104 HydrophobicContact CG-CE1 4.2Å; L61-K225 HydrophobicContact CD2-CB 4.17Å; L61-K225 HydrophobicContact CD2-CG 4.46Å; L61-Y229 HydrophobicContact CD1-CD2 3.58Å; L61-Y229 HydrophobicContact CD1-CG 3.93Å; L61-Y301 HydrophobicContact CG-CE2 4.23Å
62	I	95.8	Very high	94.4	Very high	0 Å²	0	5 Å²	5	0%	0	2%	0.024	C	C	.	.	H	α-helix	trans	-63.9	-45.4	172.2	-69.4	162.6	0	0	0	109.5	M1 F35 C54 S58 Y59 L64 S65 L66 I101 F104	M1-I62 HydrophobicContact CE-CD1 3.71Å; F35-I62 HydrophobicContact CD1-CG2 4.22Å; F35-I62 HydrophobicContact CE1-CB 3.88Å; F35-I62 HydrophobicContact CE1-CG2 3.61Å; F35-I62 HydrophobicContact CE2-CG2 4.08Å; F35-I62 HydrophobicContact CZ-CB 3.85Å; F35-I62 HydrophobicContact CZ-CD1 4.47Å; F35-I62 HydrophobicContact CZ-CG2 3.5Å; C54-I62 WeakPolarHBondContact SG-CD1 3.31Å; S58-I62 WeakPolarHBondContact O-CB 3.44Å; S58-I62 WeakPolarHBondContact O-CD1 2.96Å; S58-I62 WeakPolarHBondContact O-CG1 3.43Å; S58-I62 PolarHBondContact O-N 3.36Å; Y59-I62 PolarHBondContact O-N 3.48Å; I62-L64 PolarHBondContact O-N 3.24Å; I62-S65 WeakPolarHBondContact CA-OG 3.28Å; I62-S65 PolarHBondContact O-N 2.62Å; I62-S65 VanDerWaalsContact O-N 3.14Å; I62-S65 PolarHBondContact O-OG 2.97Å; I62-L66 HydrophobicContact CG2-CD1 4.12Å; I62-L66 PolarHBondContact O-N 3.39Å; I62-I101 HydrophobicContact CG2-CG1 4.29Å; I62-I101 HydrophobicContact CG2-CG2 4.45Å; I62-F104 HydrophobicContact CD1-CB 4.06Å; I62-F104 HydrophobicContact CG1-CB 3.56Å; I62-F104 HydrophobicContact CG1-CD2 4.35Å; I62-F104 HydrophobicContact CG1-CG 4.36Å
63	L	94.8	Very high	94.5	Very high	23 Å²	23	4.9 Å²	4.9	12%	0.12	2%	0.024	C	C	.	.	H	α-helix	trans	-58.1	-48.5	175.5	177.8	65.8	0	0	0	111.4	F35 L36 Y59 S65 L66 W67	F35-L63 HydrophobicContact CD1-CB 3.95Å; F35-L63 HydrophobicContact CD1-CD1 4.08Å; F35-L63 HydrophobicContact CE1-CB 3.95Å; L36-L63 HydrophobicContact CD1-CD1 4.25Å; L36-L63 HydrophobicContact CD2-CD1 3.51Å; L36-L63 HydrophobicContact CD2-CD2 3.49Å; L36-L63 VanDerWaalsContact CD2-CD2 3.49Å; L36-L63 HydrophobicContact CD2-CG 4.13Å; L36-L63 HydrophobicContact CG-CD1 3.49Å; L36-L63 VanDerWaalsContact CG-CD1 3.49Å; L36-L63 HydrophobicContact CG-CD2 4.43Å; Y59-L63 HydrophobicContact CE1-CD2 4.5Å; Y59-L63 WeakPolarHBondContact O-CB 3.33Å; Y59-L63 PolarHBondContact O-N 2.99Å; L63-S65 VanDerWaalsContact C-N 3.27Å; L63-S65 PolarHBondContact O-N 3.16Å; L63-L66 PolarHBondContact O-N 3.27Å; L63-W67 WeakPolarHBondContact O-CB 3.08Å; L63-W67 PolarHBondContact O-N 3.21Å
64	L	96	Very high	94.7	Very high	8 Å²	8	5.2 Å²	5.2	4%	0.042	3%	0.026	C	C	.	.	H	α-helix	trans	-57.7	-41.4	175.8	-172.5	77.2	0	0	0	111.2	G60 L61 I62 W67 I68 G221 I305 L309	G60-L64 WeakPolarHBondContact O-CB 3.49Å; G60-L64 PolarHBondContact O-N 3.43Å; L61-L64 PolarHBondContact O-N 3.18Å; I62-L64 PolarHBondContact O-N 3.24Å; L64-W67 PolarHBondContact O-N 2.97Å; L64-I68 HydrophobicContact CD1-CD1 3.9Å; L64-I68 HydrophobicContact CD1-CG1 4.38Å; L64-I68 HydrophobicContact CD2-CD1 4.28Å; L64-I68 HydrophobicContact CG-CD1 3.78Å; L64-I68 HydrophobicContact CG-CG1 4.37Å; L64-I68 WeakPolarHBondContact O-CG1 3.35Å; L64-I68 PolarHBondContact O-N 3.26Å; L64-G221 WeakPolarHBondContact CD2-O 3.33Å; L64-I305 HydrophobicContact CD1-CG2 4.5Å; L64-L309 HydrophobicContact CD1-CD2 3.77Å; L64-L309 HydrophobicContact CD1-CG 3.76Å
65	S	97.2	Very high	94.9	Very high	0 Å²	0	5.3 Å²	5.3	0%	0	3%	0.027	C	C	.	.	H	α-helix	trans	-65.9	-44.5	-179.8	72.7	0	0	0	0	113.5	L61 I62 L63 W67 C69 I222	L61-S65 WeakPolarHBondContact O-CB 3.32Å; L61-S65 PolarHBondContact O-N 2.84Å; I62-S65 WeakPolarHBondContact CA-OG 3.28Å; I62-S65 PolarHBondContact O-N 2.62Å; I62-S65 VanDerWaalsContact O-N 3.14Å; I62-S65 PolarHBondContact O-OG 2.97Å; L63-S65 VanDerWaalsContact C-N 3.27Å; L63-S65 PolarHBondContact O-N 3.16Å; S65-W67 VanDerWaalsContact C-N 3.28Å; S65-W67 PolarHBondContact O-N 3.15Å; S65-C69 VanDerWaalsContact O-CB 3.24Å; S65-C69 WeakPolarHBondContact O-CB 3.41Å; S65-C69 PolarHBondContact O-N 3.27Å; S65-C69 PolarHBondContact O-SG 3.25Å; S65-I222 VanDerWaalsContact CA-CD1 3.49Å
66	L	96.7	Very high	95	Very high	1 Å²	1	5.2 Å²	5.2	1%	0.005	3%	0.027	C	C	.	.	H	α-helix	trans	-59.5	-43	174.3	-74.5	167.8	0	0	0	110.7	I31 F35 I62 L63 S70 L97 I101	I31-L66 HydrophobicContact CB-CD2 4.32Å; I31-L66 HydrophobicContact CG2-CD1 4.11Å; I31-L66 HydrophobicContact CG2-CD2 3.73Å; F35-L66 HydrophobicContact CB-CD1 3.86Å; F35-L66 HydrophobicContact CD1-CD1 4.04Å; F35-L66 HydrophobicContact CG-CD1 3.95Å; I62-L66 HydrophobicContact CG2-CD1 4.12Å; I62-L66 PolarHBondContact O-N 3.39Å; L63-L66 PolarHBondContact O-N 3.27Å; L66-S70 PolarHBondContact O-N 3.37Å; L66-S70 PolarHBondContact O-OG 3.29Å; L66-L97 HydrophobicContact CD2-CD1 4.05Å; L66-L97 HydrophobicContact CD2-CD2 3.71Å; L66-L97 HydrophobicContact CD2-CG 4.36Å; L66-L97 HydrophobicContact CG-CD1 4.39Å; L66-I101 HydrophobicContact CD2-CD1 3.75Å; L66-I101 HydrophobicContact CG-CD1 4.12Å
67	W	97	Very high	95	Very high	26 Å²	26	6.1 Å²	6.1	10%	0.098	3%	0.031	C	C	.	.	H	α-helix	trans	-69.6	-46.2	-177.9	-166.3	-97	0	0	0	113.4	F33 L63 L64 S65 S70 L71 L427 P431	F33-W67 HydrophobicContact CE1-CZ3 4.28Å; F33-W67 HydrophobicContact CZ-CH2 4.4Å; F33-W67 HydrophobicContact CZ-CZ3 4.19Å; L63-W67 WeakPolarHBondContact O-CB 3.08Å; L63-W67 PolarHBondContact O-N 3.21Å; L64-W67 PolarHBondContact O-N 2.97Å; S65-W67 VanDerWaalsContact C-N 3.28Å; S65-W67 PolarHBondContact O-N 3.15Å; W67-S70 PolarHBondContact O-N 3.31Å; W67-S70 PolarHBondContact O-OG 2.98Å; W67-L71 HydrophobicContact CG-CD1 4.31Å; W67-L71 VanDerWaalsContact O-CG 3.3Å; W67-L71 WeakPolarHBondContact O-CG 3.27Å; W67-L71 PolarHBondContact O-N 3.35Å; W67-L71 VanDerWaalsContact O-N 3.11Å; W67-L427 HydrophobicContact CH2-CD2 4.02Å; W67-L427 HydrophobicContact CZ2-CB 4.16Å; W67-L427 HydrophobicContact CZ2-CD2 3.76Å; W67-L427 PolarHBondContact NE1-O 3.39Å; W67-P431 HydrophobicContact CZ2-CG 3.64Å
68	I	97.2	Very high	94.8	Very high	0 Å²	0	8.2 Å²	8.2	0%	0	4%	0.041	C	C	.	.	H	α-helix	trans	-70.7	-35	180	-65.5	179.9	0	0	0	110.8	L64 S70 L71 M72 M217 G221 I222	L64-I68 HydrophobicContact CD1-CD1 3.9Å; L64-I68 HydrophobicContact CD1-CG1 4.38Å; L64-I68 HydrophobicContact CD2-CD1 4.28Å; L64-I68 HydrophobicContact CG-CD1 3.78Å; L64-I68 HydrophobicContact CG-CG1 4.37Å; L64-I68 WeakPolarHBondContact O-CG1 3.35Å; L64-I68 PolarHBondContact O-N 3.26Å; I68-S70 VanDerWaalsContact C-N 3.3Å; I68-S70 PolarHBondContact O-N 2.96Å; I68-L71 PolarHBondContact O-N 2.79Å; I68-M72 PolarHBondContact O-N 2.82Å; I68-M217 HydrophobicContact CG2-CB 4.41Å; I68-G221 VanDerWaalsContact CD1-CA 3.46Å; I68-I222 HydrophobicContact CB-CD1 4.19Å; I68-I222 HydrophobicContact CD1-CG1 4.24Å; I68-I222 HydrophobicContact CG2-CD1 4.37Å
69	C	96.6	Very high	94.7	Very high	0 Å²	0	9 Å²	9	0%	0	5%	0.045	C	C	.	.	H	α-helix	trans	-69.4	-23.3	176.4	-72.4	0	0	0	0	113.8	M28 S65 M72 L97	M28-C69 HydrophobicContact CE-CB 3.92Å; S65-C69 VanDerWaalsContact O-CB 3.24Å; S65-C69 WeakPolarHBondContact O-CB 3.41Å; S65-C69 PolarHBondContact O-N 3.27Å; S65-C69 PolarHBondContact O-SG 3.25Å; C69-M72 HydrophobicContact CB-SD 4.11Å; C69-M72 WeakPolarHBondContact O-CG 3.44Å; C69-L97 HydrophobicContact CB-CB 4.34Å; C69-L97 HydrophobicContact CB-CD1 4.07Å
70	S	96.1	Very high	94.5	Very high	0 Å²	0	10.1 Å²	10.1	0%	0	5%	0.051	C	C	.	.	H	α-helix	trans	-80.2	-37.6	169.1	64.2	0	0	0	0	111.6	F29 L66 W67 I68 L73 L74	F29-S70 WeakPolarHBondContact CD1-OG 3.06Å; F29-S70 WeakPolarHBondContact CE1-OG 3.22Å; F29-S70 WeakPolarHBondContact CZ-OG 3.4Å; L66-S70 PolarHBondContact O-N 3.37Å; L66-S70 PolarHBondContact O-OG 3.29Å; W67-S70 PolarHBondContact O-N 3.31Å; W67-S70 PolarHBondContact O-OG 2.98Å; I68-S70 VanDerWaalsContact C-N 3.3Å; I68-S70 PolarHBondContact O-N 2.96Å; S70-L73 PolarHBondContact O-N 3.3Å; S70-L74 PolarHBondContact O-N 3.42Å
71	L	96.6	Very high	94.2	Very high	0 Å²	0	14.9 Å²	14.9	0%	0	7%	0.071	C	C	.	.	H	α-helix	trans	-67.1	-34.1	177	-70.9	167.7	0	0	0	113.6	F29 W67 I68 L73 L74 A75 M217 L424 L427	F29-L71 HydrophobicContact CZ-CD2 4.26Å; W67-L71 HydrophobicContact CG-CD1 4.31Å; W67-L71 VanDerWaalsContact O-CG 3.3Å; W67-L71 WeakPolarHBondContact O-CG 3.27Å; W67-L71 PolarHBondContact O-N 3.35Å; W67-L71 VanDerWaalsContact O-N 3.11Å; I68-L71 PolarHBondContact O-N 2.79Å; L71-L73 VanDerWaalsContact C-N 3.26Å; L71-L73 PolarHBondContact O-N 2.84Å; L71-L74 HydrophobicContact CD2-CD1 4.13Å; L71-L74 WeakPolarHBondContact O-CB 3.42Å; L71-L74 PolarHBondContact O-N 3.26Å; L71-A75 PolarHBondContact O-N 3.29Å; L71-M217 HydrophobicContact CB-CE 3.81Å; L71-L424 HydrophobicContact CD2-CG 4.48Å; L71-L427 HydrophobicContact CD2-CB 3.54Å; L71-L427 HydrophobicContact CD2-CD1 3.79Å; L71-L427 HydrophobicContact CD2-CG 4.33Å
72	M	96	Very high	93.9	Very high	0 Å²	0	20.2 Å²	20.2	0%	0	10%	0.096	C	C	.	.	H	α-helix	trans	-62.1	-36	176.5	65.3	-179.6	-53.2	0	0	112.2	I68 C69 A75 S76 I93 L126 S214 I218	I68-M72 PolarHBondContact O-N 2.82Å; C69-M72 HydrophobicContact CB-SD 4.11Å; C69-M72 WeakPolarHBondContact O-CG 3.44Å; M72-A75 WeakPolarHBondContact O-CB 3.28Å; M72-A75 PolarHBondContact O-N 3Å; M72-S76 PolarHBondContact O-N 3.5Å; M72-S76 PolarHBondContact O-OG 3.07Å; M72-I93 HydrophobicContact CE-CB 4.39Å; M72-I93 HydrophobicContact CE-CD1 3.38Å; M72-I93 HydrophobicContact CE-CG1 3.4Å; M72-I93 HydrophobicContact CE-CG2 4.23Å; M72-I93 HydrophobicContact CG-CD1 4.23Å; M72-I93 HydrophobicContact CG-CG2 4.34Å; M72-I93 HydrophobicContact SD-CB 4.24Å; M72-I93 HydrophobicContact SD-CD1 3.9Å; M72-I93 HydrophobicContact SD-CG1 3.85Å; M72-I93 HydrophobicContact SD-CG2 3.46Å; M72-I93 WeakPolarHBondContact SD-CG2 3.12Å; M72-L126 HydrophobicContact CE-CD1 4.39Å; M72-S214 VanDerWaalsContact CE-CB 3.46Å; M72-I218 HydrophobicContact CE-CD1 3.09Å; M72-I218 HydrophobicContact CE-CG1 3.88Å; M72-I218 HydrophobicContact SD-CD1 3.53Å; M72-I218 VanDerWaalsContact SD-CD1 3.53Å; M72-I218 HydrophobicContact SD-CG1 3.85Å
73	L	95.1	Very high	93.5	Very high	1 Å²	1	25 Å²	25	1%	0.005	12%	0.121	C	C	.	.	H	α-helix	trans	-68.1	-37.5	177.4	-71.2	175.3	0	0	0	111.1	Y21 V24 Q25 S70 L71 A75 S76 F89 L90 I93	Y21-L73 WeakPolarHBondContact CE1-O 2.92Å; Y21-L73 HydrophobicContact CE2-CD2 4.25Å; Y21-L73 PolarHBondContact OH-O 3.21Å; V24-L73 HydrophobicContact CG1-CD1 4.32Å; Q25-L73 HydrophobicContact CB-CB 4.14Å; Q25-L73 HydrophobicContact CB-CD1 3.99Å; Q25-L73 HydrophobicContact CG-CB 3.89Å; Q25-L73 HydrophobicContact CG-CD1 4.34Å; S70-L73 PolarHBondContact O-N 3.3Å; L71-L73 VanDerWaalsContact C-N 3.26Å; L71-L73 PolarHBondContact O-N 2.84Å; L73-A75 VanDerWaalsContact C-N 3.34Å; L73-S76 PolarHBondContact O-OG 3.49Å; L73-F89 HydrophobicContact CD2-CE1 4.11Å; L73-L90 HydrophobicContact CD1-CD2 4.47Å; L73-L90 HydrophobicContact CD2-CD2 3.43Å; L73-L90 VanDerWaalsContact CD2-CD2 3.43Å; L73-I93 HydrophobicContact CD2-CD1 3.35Å; L73-I93 HydrophobicContact CD2-CG2 4.48Å; L73-I93 HydrophobicContact CG-CD1 4.12Å; L73-I93 HydrophobicContact CG-CG2 4.44Å
74	L	95	Very high	93.1	Very high	8 Å²	8	28 Å²	28	4%	0.042	14%	0.138	C	C	.	.	H	α-helix	trans	-62.2	-42.6	170.8	-79.7	169	0	0	0	111.7	W22 Q25 F29 S70 L71 R420 L423 L424 L427	W22-L74 HydrophobicContact CZ3-CD2 4.25Å; Q25-L74 VanDerWaalsContact CD-CG 3.44Å; Q25-L74 HydrophobicContact CG-CG 4.41Å; F29-L74 HydrophobicContact CE2-CD1 3.71Å; F29-L74 HydrophobicContact CE2-CG 4.28Å; F29-L74 HydrophobicContact CZ-CD1 3.64Å; S70-L74 PolarHBondContact O-N 3.42Å; L71-L74 HydrophobicContact CD2-CD1 4.13Å; L71-L74 WeakPolarHBondContact O-CB 3.42Å; L71-L74 PolarHBondContact O-N 3.26Å; L74-R420 HydrophobicContact CD2-CG 4.39Å; L74-R420 WeakPolarHBondContact O-CD 3.3Å; L74-R420 PolarHBondContact O-NH1 3.13Å; L74-L423 HydrophobicContact CD1-CD2 3.65Å; L74-L423 HydrophobicContact CD2-CD2 4.06Å; L74-L424 HydrophobicContact CB-CD1 4.1Å; L74-L427 HydrophobicContact CD1-CD1 3.94Å
75	A	94.6	Very high	92.9	Very high	2 Å²	2	36.1 Å²	36.1	2%	0.017	17%	0.169	C	C	.	.	H	α-helix	trans	-63.9	-42.8	-178.7	0	0	0	0	0	111.6	L71 M72 L73 E77 V213 M217 R420 L424	L71-A75 PolarHBondContact O-N 3.29Å; M72-A75 WeakPolarHBondContact O-CB 3.28Å; M72-A75 PolarHBondContact O-N 3Å; L73-A75 VanDerWaalsContact C-N 3.34Å; A75-E77 VanDerWaalsContact C-N 3.29Å; A75-E77 PolarHBondContact O-N 3.28Å; A75-E77 VanDerWaalsContact O-N 3.09Å; A75-V213 HydrophobicContact CB-CG1 3.99Å; A75-M217 HydrophobicContact CB-SD 3.65Å; A75-R420 PolarHBondContact O-NH1 3.23Å; A75-L424 HydrophobicContact CB-CD1 3.62Å
76	S	93	Very high	92.7	Very high	6 Å²	6	37.6 Å²	37.6	4%	0.042	18%	0.175	C	C	.	.	T	Hydrogen-bonded Turn	trans	-85.9	38.4	-171.1	58.5	0	0	0	0	115.5	Y21 M72 L73 M78 I79 F89	Y21-S76 PolarHBondContact OH-O 3.42Å; Y21-S76 PolarHBondContact OH-OG 2.92Å; M72-S76 PolarHBondContact O-N 3.5Å; M72-S76 PolarHBondContact O-OG 3.07Å; L73-S76 PolarHBondContact O-OG 3.49Å; S76-M78 PolarHBondContact O-N 3.4Å; S76-I79 PolarHBondContact O-N 3.35Å; S76-F89 WeakPolarHBondContact OG-CE1 3.47Å; S76-F89 WeakPolarHBondContact OG-CZ 3.47Å
77	E	90	Very high	92.5	Very high	28 Å²	28	39.5 Å²	39.5	13%	0.131	19%	0.186	C	C	.	.	H	α-helix	trans	-60.7	-32.5	176.3	-173.9	-167.9	-162.8	0	0	112.3	W22 A75 I79 N80 K81 R420	W22-E77 HydrophobicContact CH2-CB 4.33Å; W22-E77 HydrophobicContact CH2-CG 4.05Å; W22-E77 HydrophobicContact CZ2-CG 4.05Å; A75-E77 VanDerWaalsContact C-N 3.29Å; A75-E77 PolarHBondContact O-N 3.28Å; A75-E77 VanDerWaalsContact O-N 3.09Å; E77-I79 PolarHBondContact O-N 3.27Å; E77-N80 CarbonylContact O-C 3.46Å; E77-N80 WeakPolarHBondContact O-CA 3.4Å; E77-N80 WeakPolarHBondContact O-CB 3.43Å; E77-N80 PolarHBondContact O-N 3.49Å; E77-K81 HydrophobicContact CG-CD 3.99Å; E77-K81 HydrophobicContact CG-CG 4.15Å; E77-K81 PolarHBondContact O-N 2.93Å; E77-K81 WeakPolarHBondContact OE1-CE 3.34Å; E77-K81 IonicContact OE1-NZ 2.96Å; E77-K81 PolarHBondContact OE1-NZ 3.24Å; E77-K81 IonicContact OE2-NZ 3.26Å; E77-K81 PolarHBondContact OE2-NZ 3.13Å; E77-R420 VanDerWaalsContact CB-CZ 3.44Å; E77-R420 IonicContact OE2-CZ 3.52Å; E77-R420 IonicContact OE2-NE 3.03Å; E77-R420 PolarHBondContact OE2-NE 3.36Å; E77-R420 IonicContact OE2-NH1 2.83Å; E77-R420 IonicContact OE2-NH2 3.59Å; E77-R420 PolarHBondContact OE2-NH2 3.24Å
78	M	88.9	Confident	92.4	Very high	58 Å²	58	42.6 Å²	42.6	29%	0.286	20%	0.203	S	C	.	.	H	α-helix	trans	-57.4	-33.8	179.2	-68.4	-63	-79.5	0	0	112.2	S76 K81 H82 E323	S76-M78 PolarHBondContact O-N 3.4Å; M78-K81 PolarHBondContact O-N 2.94Å; M78-K81 HydrophobicContact SD-CD 4.41Å; M78-H82 WeakPolarHBondContact CE-NE2 3.37Å; M78-H82 WeakPolarHBondContact O-CB 3.44Å; M78-H82 PolarHBondContact O-CD2 3.48Å; M78-H82 PolarHBondContact O-N 3.43Å; M78-E323 HydrophobicContact CG-CG 4.25Å; M78-E323 WeakPolarHBondContact CG-OE1 3.16Å
79	I	90.5	Very high	92.3	Very high	17 Å²	17	42.6 Å²	42.6	9%	0.087	20%	0.203	C	C	.	.	H	α-helix	trans	-66.6	-41.2	176.4	-57	179.9	0	0	0	110.6	S76 E77 N83 N84 F89 W130	S76-I79 PolarHBondContact O-N 3.35Å; E77-I79 PolarHBondContact O-N 3.27Å; I79-N83 PolarHBondContact O-N 3.31Å; I79-N83 VanDerWaalsContact O-N 3.12Å; I79-N84 HydrophobicContact CG2-CB 4.42Å; I79-N84 WeakPolarHBondContact CG2-O 3.15Å; I79-N84 PolarHBondContact O-N 2.7Å; I79-N84 VanDerWaalsContact O-N 3.16Å; I79-F89 HydrophobicContact CD1-CD1 4.21Å; I79-F89 HydrophobicContact CD1-CD2 3.7Å; I79-F89 HydrophobicContact CD1-CE1 3.95Å; I79-F89 HydrophobicContact CD1-CE2 3.4Å; I79-F89 VanDerWaalsContact CD1-CE2 3.4Å; I79-F89 HydrophobicContact CD1-CG 4.07Å; I79-F89 HydrophobicContact CD1-CZ 3.52Å; I79-F89 HydrophobicContact CG2-CB 4.34Å; I79-F89 HydrophobicContact CG2-CD1 4.41Å; I79-F89 HydrophobicContact CG2-CG 4.25Å; I79-W130 HydrophobicContact CD1-CB 4.33Å; I79-W130 HydrophobicContact CD1-CG 4.05Å
80	N	88.2	Confident	92.2	Very high	29 Å²	29	42.7 Å²	42.7	16%	0.155	20%	0.204	C	C	.	.	H	α-helix	trans	-68.9	-41.6	176.4	-167.3	24.8	0	0	0	111.4	Y21 E77 N83	Y21-N80 HydrophobicContact CD1-CB 4.28Å; Y21-N80 HydrophobicContact CD2-CB 4.16Å; Y21-N80 HydrophobicContact CE1-CB 4.39Å; Y21-N80 HydrophobicContact CE2-CB 4.26Å; Y21-N80 HydrophobicContact CG-CB 4.19Å; E77-N80 CarbonylContact O-C 3.46Å; E77-N80 WeakPolarHBondContact O-CA 3.4Å; E77-N80 WeakPolarHBondContact O-CB 3.43Å; E77-N80 PolarHBondContact O-N 3.49Å; N80-N83 PolarHBondContact O-N 3.2Å; N80-N83 PolarHBondContact O-OD1 3Å
81	K	88	Confident	92.2	Very high	103 Å²	103	44.2 Å²	44.2	45%	0.448	21%	0.212	S	C	.	.	H	α-helix	trans	-62.7	-43.5	178	-79.5	176.4	168.9	163	0	113.1	E77 M78 N83	E77-K81 HydrophobicContact CG-CD 3.99Å; E77-K81 HydrophobicContact CG-CG 4.15Å; E77-K81 PolarHBondContact O-N 2.93Å; E77-K81 WeakPolarHBondContact OE1-CE 3.34Å; E77-K81 IonicContact OE1-NZ 2.96Å; E77-K81 PolarHBondContact OE1-NZ 3.24Å; E77-K81 IonicContact OE2-NZ 3.26Å; E77-K81 PolarHBondContact OE2-NZ 3.13Å; M78-K81 PolarHBondContact O-N 2.94Å; M78-K81 HydrophobicContact SD-CD 4.41Å; K81-N83 VanDerWaalsContact C-N 3.31Å
82	H	89.1	Confident	92.1	Very high	114 Å²	114	45.1 Å²	45.1	53%	0.528	22%	0.217	S	C	.	.	T	Hydrogen-bonded Turn	trans	-84	-3.2	178.4	-65.2	-59.4	0	0	0	113.7	M78 N84	M78-H82 WeakPolarHBondContact CE-NE2 3.37Å; M78-H82 WeakPolarHBondContact O-CB 3.44Å; M78-H82 PolarHBondContact O-CD2 3.48Å; M78-H82 PolarHBondContact O-N 3.43Å; H82-N84 PolarHBondContact O-N 3.32Å; H82-N84 PolarHBondContact O-OD1 3.22Å
83	N	86.8	Confident	92.2	Very high	100 Å²	100	45.2 Å²	45.2	54%	0.535	22%	0.217	S	C	.	.	T	Hydrogen-bonded Turn	trans	52.5	31.2	-172.9	-72.8	-51.9	0	0	0	113.9	I79 N80 K81 Y85 K86	I79-N83 PolarHBondContact O-N 3.31Å; I79-N83 VanDerWaalsContact O-N 3.12Å; N80-N83 PolarHBondContact O-N 3.2Å; N80-N83 PolarHBondContact O-OD1 3Å; K81-N83 VanDerWaalsContact C-N 3.31Å; N83-Y85 PolarHBondContact O-N 3.26Å; N83-K86 PolarHBondContact OD1-NZ 3.45Å; N83-K86 VanDerWaalsContact OD1-NZ 3.09Å
84	N	87.7	Confident	92.2	Very high	88 Å²	88	45.2 Å²	45.2	47%	0.471	22%	0.217	S	C	.	.	S	Bend	trans	-74.7	87.1	-178.9	-74.3	-3.5	0	0	0	111.1	I79 H82 K86 W130	I79-N84 HydrophobicContact CG2-CB 4.42Å; I79-N84 WeakPolarHBondContact CG2-O 3.15Å; I79-N84 PolarHBondContact O-N 2.7Å; I79-N84 VanDerWaalsContact O-N 3.16Å; H82-N84 PolarHBondContact O-N 3.32Å; H82-N84 PolarHBondContact O-OD1 3.22Å; N84-K86 PolarHBondContact O-N 3.4Å; N84-K86 VanDerWaalsContact O-N 3.17Å; N84-W130 PolarHBondContact O-NE1 3.36Å; N84-W130 VanDerWaalsContact O-NE1 3.07Å
85	Y	91.1	Very high	92.3	Very high	178 Å²	178	47.8 Å²	47.8	70%	0.698	23%	0.23	S	C	*	.	S	Bend	trans	46.1	46.5	179.3	-65.8	-74.2	0	0	0	113.6	N83 N87 L88 F89	N83-Y85 PolarHBondContact O-N 3.26Å; Y85-N87 VanDerWaalsContact C-N 3.28Å; Y85-N87 PolarHBondContact O-N 3.09Å; Y85-L88 HydrophobicContact CD1-CD1 3.95Å; Y85-L88 HydrophobicContact CG-CD1 4.34Å; Y85-L88 PolarHBondContact O-N 2.88Å; Y85-F89 PolarHBondContact O-N 3.14Å
86	K	92.4	Very high	92.4	Very high	31 Å²	31	47.7 Å²	47.7	14%	0.135	23%	0.229	C	C	.	.	H	α-helix	trans	-55.9	-38.2	-173.4	70.2	-174.3	177.6	-168.9	0	113.7	N83 N84 F89 L90	N83-K86 PolarHBondContact OD1-NZ 3.45Å; N83-K86 VanDerWaalsContact OD1-NZ 3.09Å; N84-K86 PolarHBondContact O-N 3.4Å; N84-K86 VanDerWaalsContact O-N 3.17Å; K86-F89 WeakPolarHBondContact O-CB 3.48Å; K86-F89 PolarHBondContact O-N 3.45Å; K86-L90 WeakPolarHBondContact O-CG 3.16Å; K86-L90 PolarHBondContact O-N 3.3Å
87	N	93	Very high	92.6	Very high	41 Å²	41	47.4 Å²	47.4	22%	0.219	23%	0.227	C	C	.	.	H	α-helix	trans	-68.6	-40.9	-178.1	-63.4	2.2	0	0	0	111.4	C15 Y85 F89 L90 L91	C15-N87 PolarHBondContact O-OD1 2.93Å; Y85-N87 VanDerWaalsContact C-N 3.28Å; Y85-N87 PolarHBondContact O-N 3.09Å; N87-F89 VanDerWaalsContact C-N 3.32Å; N87-L90 PolarHBondContact O-N 3.22Å; N87-L91 WeakPolarHBondContact O-CB 3.27Å; N87-L91 PolarHBondContact O-N 2.86Å
88	L	93.8	Very high	92.9	Very high	90 Å²	90	47.4 Å²	47.4	47%	0.471	23%	0.228	S	C	.	.	H	α-helix	trans	-67	-36.2	175.4	-67.2	174.9	0	0	0	111.4	Y85 L91 N92 W130	Y85-L88 HydrophobicContact CD1-CD1 3.95Å; Y85-L88 HydrophobicContact CG-CD1 4.34Å; Y85-L88 PolarHBondContact O-N 2.88Å; L88-L91 PolarHBondContact O-N 3.46Å; L88-N92 WeakPolarHBondContact O-CB 2.99Å; L88-N92 PolarHBondContact O-N 3.42Å; L88-W130 HydrophobicContact CB-CH2 4.46Å; L88-W130 HydrophobicContact CB-CZ2 4.38Å
89	F	95.1	Very high	93.3	Very high	0 Å²	0	45.7 Å²	45.7	0%	0	22%	0.22	C	C	.	.	H	α-helix	trans	-61.7	-50.2	174.8	-178.4	-105.1	0	0	0	111.6	Y21 L73 S76 I79 Y85 K86 N87 L91 N92 I93 L126 W130 S214	Y21-F89 HydrophobicContact CE2-CD1 4.37Å; L73-F89 HydrophobicContact CD2-CE1 4.11Å; S76-F89 WeakPolarHBondContact OG-CE1 3.47Å; S76-F89 WeakPolarHBondContact OG-CZ 3.47Å; I79-F89 HydrophobicContact CD1-CD1 4.21Å; I79-F89 HydrophobicContact CD1-CD2 3.7Å; I79-F89 HydrophobicContact CD1-CE1 3.95Å; I79-F89 HydrophobicContact CD1-CE2 3.4Å; I79-F89 VanDerWaalsContact CD1-CE2 3.4Å; I79-F89 HydrophobicContact CD1-CG 4.07Å; I79-F89 HydrophobicContact CD1-CZ 3.52Å; I79-F89 HydrophobicContact CG2-CB 4.34Å; I79-F89 HydrophobicContact CG2-CD1 4.41Å; I79-F89 HydrophobicContact CG2-CG 4.25Å; Y85-F89 PolarHBondContact O-N 3.14Å; K86-F89 WeakPolarHBondContact O-CB 3.48Å; K86-F89 PolarHBondContact O-N 3.45Å; N87-F89 VanDerWaalsContact C-N 3.32Å; F89-L91 VanDerWaalsContact C-N 3.35Å; F89-L91 PolarHBondContact O-N 2.94Å; F89-N92 PolarHBondContact O-N 3.44Å; F89-I93 HydrophobicContact CD1-CD1 3.72Å; F89-I93 HydrophobicContact CD2-CD1 4.46Å; F89-I93 HydrophobicContact CE1-CD1 3.2Å; F89-I93 HydrophobicContact CE1-CG1 4.42Å; F89-I93 HydrophobicContact CE2-CD1 4.03Å; F89-I93 HydrophobicContact CG-CD1 4.33Å; F89-I93 HydrophobicContact CZ-CD1 3.4Å; F89-I93 HydrophobicContact CZ-CG1 4.41Å; F89-I93 WeakPolarHBondContact O-CG1 3.34Å; F89-I93 PolarHBondContact O-N 2.96Å; F89-I93 VanDerWaalsContact O-N 3.11Å; F89-L126 HydrophobicContact CD2-CD2 3.87Å; F89-L126 HydrophobicContact CE2-CD2 3.63Å; F89-W130 VanDerWaalsContact CA-CH2 3.49Å; F89-W130 HydrophobicContact CB-CH2 3.95Å; F89-W130 HydrophobicContact CB-CZ2 3.37Å; F89-W130 AromaticContact CD2-CD2 3.66Å; F89-W130 HydrophobicContact CD2-CD2 3.66Å; F89-W130 AromaticContact CD2-CE2 3.67Å; F89-W130 AromaticContact CD2-CE3 3.89Å; F89-W130 HydrophobicContact CD2-CE3 3.89Å; F89-W130 HydrophobicContact CD2-CG 4.21Å; F89-W130 HydrophobicContact CD2-CH2 4.13Å; F89-W130 AromaticContact CD2-CZ2 3.93Å; F89-W130 HydrophobicContact CD2-CZ2 3.93Å; F89-W130 HydrophobicContact CD2-CZ3 4.11Å; F89-W130 HydrophobicContact CE2-CD2 4.4Å; F89-W130 HydrophobicContact CG-CZ2 4.14Å; F89-S214 WeakPolarHBondContact CE2-OG 3.45Å
90	L	94.9	Very high	93.7	Very high	2 Å²	2	44.9 Å²	44.9	1%	0.01	22%	0.216	C	C	.	.	H	α-helix	trans	-58.5	-46.7	176.8	-70.5	175.9	0	0	0	111.6	C15 Y21 V24 L73 K86 N87 N92 I93 I94	C15-L90 HydrophobicContact CB-CB 4.04Å; Y21-L90 HydrophobicContact CD2-CD1 3.92Å; Y21-L90 HydrophobicContact CD2-CD2 3.58Å; Y21-L90 HydrophobicContact CD2-CG 3.9Å; Y21-L90 HydrophobicContact CE2-CD2 3.66Å; Y21-L90 HydrophobicContact CE2-CG 4.23Å; Y21-L90 HydrophobicContact CG-CD2 4.37Å; V24-L90 HydrophobicContact CG1-CD2 4.4Å; L73-L90 HydrophobicContact CD1-CD2 4.47Å; L73-L90 HydrophobicContact CD2-CD2 3.43Å; L73-L90 VanDerWaalsContact CD2-CD2 3.43Å; K86-L90 WeakPolarHBondContact O-CG 3.16Å; K86-L90 PolarHBondContact O-N 3.3Å; N87-L90 PolarHBondContact O-N 3.22Å; L90-N92 PolarHBondContact O-N 3.01Å; L90-I93 PolarHBondContact O-N 3Å; L90-I94 WeakPolarHBondContact O-CG1 3.44Å; L90-I94 PolarHBondContact O-N 3.48Å
91	L	95.7	Very high	94	Very high	32 Å²	32	43.5 Å²	43.5	17%	0.168	21%	0.209	C	C	.	.	H	α-helix	trans	-59.4	-45.2	178.1	177.2	138.1	0	0	0	111.9	I12 F16 N87 L88 F89 I93 I94 I95	I12-L91 HydrophobicContact CG2-CD1 4.42Å; F16-L91 HydrophobicContact CE1-CD1 4.21Å; F16-L91 HydrophobicContact CE2-CD1 3.76Å; F16-L91 HydrophobicContact CZ-CD1 3.3Å; N87-L91 WeakPolarHBondContact O-CB 3.27Å; N87-L91 PolarHBondContact O-N 2.86Å; L88-L91 PolarHBondContact O-N 3.46Å; F89-L91 VanDerWaalsContact C-N 3.35Å; F89-L91 PolarHBondContact O-N 2.94Å; L91-I93 VanDerWaalsContact C-N 3.27Å; L91-I93 PolarHBondContact O-N 3.16Å; L91-I94 PolarHBondContact O-N 3.31Å; L91-I95 HydrophobicContact CD2-CD1 3.39Å; L91-I95 HydrophobicContact CD2-CG1 4.44Å; L91-I95 HydrophobicContact CG-CD1 3.83Å; L91-I95 HydrophobicContact CG-CG1 4.46Å; L91-I95 VanDerWaalsContact O-CG1 3.31Å; L91-I95 WeakPolarHBondContact O-CG1 3.31Å; L91-I95 PolarHBondContact O-N 2.98Å
92	N	96.3	Very high	94.4	Very high	20 Å²	20	39.4 Å²	39.4	11%	0.107	19%	0.192	C	C	.	.	H	α-helix	trans	-61	-36.8	177.6	-79.1	-13	0	0	0	112.4	L88 F89 L90 L96 W130	L88-N92 WeakPolarHBondContact O-CB 2.99Å; L88-N92 PolarHBondContact O-N 3.42Å; F89-N92 PolarHBondContact O-N 3.44Å; L90-N92 PolarHBondContact O-N 3.01Å; N92-L96 VanDerWaalsContact O-CB 3.27Å; N92-L96 WeakPolarHBondContact O-CB 3.49Å; N92-L96 PolarHBondContact O-N 3.23Å; N92-W130 WeakPolarHBondContact ND2-CH2 2.83Å; N92-W130 WeakPolarHBondContact ND2-CZ3 3.42Å
93	I	96.2	Very high	94.8	Very high	1 Å²	1	34 Å²	34	1%	0.005	17%	0.167	C	C	.	.	H	α-helix	trans	-67.4	-44.7	177.4	-68.5	174.8	0	0	0	111.6	M72 L73 F89 L90 L91 L96 L97	M72-I93 HydrophobicContact CE-CB 4.39Å; M72-I93 HydrophobicContact CE-CD1 3.38Å; M72-I93 HydrophobicContact CE-CG1 3.4Å; M72-I93 HydrophobicContact CE-CG2 4.23Å; M72-I93 HydrophobicContact CG-CD1 4.23Å; M72-I93 HydrophobicContact CG-CG2 4.34Å; M72-I93 HydrophobicContact SD-CB 4.24Å; M72-I93 HydrophobicContact SD-CD1 3.9Å; M72-I93 HydrophobicContact SD-CG1 3.85Å; M72-I93 HydrophobicContact SD-CG2 3.46Å; M72-I93 WeakPolarHBondContact SD-CG2 3.12Å; L73-I93 HydrophobicContact CD2-CD1 3.35Å; L73-I93 HydrophobicContact CD2-CG2 4.48Å; L73-I93 HydrophobicContact CG-CD1 4.12Å; L73-I93 HydrophobicContact CG-CG2 4.44Å; F89-I93 HydrophobicContact CD1-CD1 3.72Å; F89-I93 HydrophobicContact CD2-CD1 4.46Å; F89-I93 HydrophobicContact CE1-CD1 3.2Å; F89-I93 HydrophobicContact CE1-CG1 4.42Å; F89-I93 HydrophobicContact CE2-CD1 4.03Å; F89-I93 HydrophobicContact CG-CD1 4.33Å; F89-I93 HydrophobicContact CZ-CD1 3.4Å; F89-I93 HydrophobicContact CZ-CG1 4.41Å; F89-I93 WeakPolarHBondContact O-CG1 3.34Å; F89-I93 PolarHBondContact O-N 2.96Å; F89-I93 VanDerWaalsContact O-N 3.11Å; L90-I93 PolarHBondContact O-N 3Å; L91-I93 VanDerWaalsContact C-N 3.27Å; L91-I93 PolarHBondContact O-N 3.16Å; I93-L96 PolarHBondContact O-N 2.75Å; I93-L97 PolarHBondContact O-N 2.93Å
94	I	96.3	Very high	95.2	Very high	2 Å²	2	29.2 Å²	29.2	1%	0.01	14%	0.141	C	C	.	.	H	α-helix	trans	-66.4	-42.6	179.2	-62.9	-170.9	0	0	0	110.8	L11 I12 C15 V24 L90 L91 L96 L97 L98	L11-I94 HydrophobicContact CB-CD1 3.73Å; I12-I94 HydrophobicContact CG1-CG2 3.96Å; C15-I94 WeakPolarHBondContact SG-CD1 3.37Å; V24-I94 HydrophobicContact CG1-CD1 3.92Å; L90-I94 WeakPolarHBondContact O-CG1 3.44Å; L90-I94 PolarHBondContact O-N 3.48Å; L91-I94 PolarHBondContact O-N 3.31Å; I94-L96 VanDerWaalsContact C-N 3.32Å; I94-L96 PolarHBondContact O-N 3.27Å; I94-L97 PolarHBondContact O-N 3.25Å; I94-L98 WeakPolarHBondContact O-CB 3.19Å; I94-L98 PolarHBondContact O-N 3.12Å
95	I	96.8	Very high	95.5	Very high	61 Å²	61	25 Å²	25	31%	0.313	12%	0.119	S	C	.	.	H	α-helix	trans	-60.3	-45.6	175.5	-68.3	172.3	0	0	0	110.1	L91 L97 L98 L99 P122	L91-I95 HydrophobicContact CD2-CD1 3.39Å; L91-I95 HydrophobicContact CD2-CG1 4.44Å; L91-I95 HydrophobicContact CG-CD1 3.83Å; L91-I95 HydrophobicContact CG-CG1 4.46Å; L91-I95 VanDerWaalsContact O-CG1 3.31Å; L91-I95 WeakPolarHBondContact O-CG1 3.31Å; L91-I95 PolarHBondContact O-N 2.98Å; I95-L97 PolarHBondContact O-N 3.4Å; I95-L98 PolarHBondContact O-N 3.41Å; I95-L99 HydrophobicContact CG2-CD1 4.1Å; I95-L99 HydrophobicContact CG2-CG 4.41Å; I95-L99 WeakPolarHBondContact O-CG 3.26Å; I95-L99 PolarHBondContact O-N 3.07Å; I95-P122 HydrophobicContact CG2-CG 3.89Å
96	L	97.2	Very high	95.7	Very high	0 Å²	0	16.6 Å²	16.6	0%	0	9%	0.085	C	C	.	.	H	α-helix	trans	-60.6	-46.2	177.5	-177.7	59.9	0	0	0	111.8	N92 I93 I94 L98 L99 L100 P122 T123 L126 I218	N92-L96 VanDerWaalsContact O-CB 3.27Å; N92-L96 WeakPolarHBondContact O-CB 3.49Å; N92-L96 PolarHBondContact O-N 3.23Å; I93-L96 PolarHBondContact O-N 2.75Å; I94-L96 VanDerWaalsContact C-N 3.32Å; I94-L96 PolarHBondContact O-N 3.27Å; L96-L98 VanDerWaalsContact C-N 3.33Å; L96-L98 PolarHBondContact O-N 3Å; L96-L99 PolarHBondContact O-N 3.46Å; L96-L100 HydrophobicContact CD1-CD1 4.18Å; L96-L100 HydrophobicContact CD1-CG 4.24Å; L96-L100 HydrophobicContact CG-CD1 3.95Å; L96-L100 HydrophobicContact CG-CG 4.43Å; L96-L100 WeakPolarHBondContact O-CB 3.45Å; L96-L100 VanDerWaalsContact O-CG 3.22Å; L96-L100 WeakPolarHBondContact O-CG 3.34Å; L96-L100 PolarHBondContact O-N 2.97Å; L96-P122 HydrophobicContact CB-CB 3.85Å; L96-P122 HydrophobicContact CB-CG 4.38Å; L96-P122 HydrophobicContact CD1-CB 4.11Å; L96-P122 HydrophobicContact CD1-CG 4.43Å; L96-P122 HydrophobicContact CG-CB 4.43Å; L96-T123 HydrophobicContact CD1-CG2 3.84Å; L96-T123 HydrophobicContact CD2-CG2 4.1Å; L96-L126 HydrophobicContact CD2-CD1 3.91Å; L96-I218 HydrophobicContact CD2-CB 4.47Å; L96-I218 HydrophobicContact CD2-CD1 3.33Å; L96-I218 HydrophobicContact CD2-CG1 4.24Å; L96-I218 HydrophobicContact CD2-CG2 3.81Å
97	L	97	Very high	95.7	Very high	0 Å²	0	15.6 Å²	15.6	0%	0	8%	0.082	C	C	.	.	H	α-helix	trans	-59.9	-45.1	176.2	177.3	66.3	0	0	0	111.3	L8 M28 L66 C69 I93 I94 I95 L99 L100 I101	L8-L97 HydrophobicContact CD1-CD2 3.84Å; L8-L97 HydrophobicContact CD1-CG 3.93Å; L8-L97 HydrophobicContact CD2-CD2 3.45Å; L8-L97 VanDerWaalsContact CD2-CD2 3.45Å; L8-L97 HydrophobicContact CD2-CG 4.38Å; L8-L97 HydrophobicContact CG-CD2 4.32Å; M28-L97 HydrophobicContact CE-CB 4.37Å; M28-L97 HydrophobicContact CE-CD2 3.17Å; M28-L97 HydrophobicContact CE-CG 4.31Å; M28-L97 HydrophobicContact SD-CD2 3.67Å; L66-L97 HydrophobicContact CD2-CD1 4.05Å; L66-L97 HydrophobicContact CD2-CD2 3.71Å; L66-L97 HydrophobicContact CD2-CG 4.36Å; L66-L97 HydrophobicContact CG-CD1 4.39Å; C69-L97 HydrophobicContact CB-CB 4.34Å; C69-L97 HydrophobicContact CB-CD1 4.07Å; I93-L97 PolarHBondContact O-N 2.93Å; I94-L97 PolarHBondContact O-N 3.25Å; I95-L97 PolarHBondContact O-N 3.4Å; L97-L99 VanDerWaalsContact C-N 3.33Å; L97-L99 PolarHBondContact O-N 3.42Å; L97-L100 PolarHBondContact O-N 3.42Å; L97-I101 HydrophobicContact CD1-CD1 4.03Å; L97-I101 HydrophobicContact CD1-CG1 4.04Å; L97-I101 HydrophobicContact CD2-CD1 4.47Å; L97-I101 HydrophobicContact CG-CD1 4.03Å; L97-I101 HydrophobicContact CG-CG1 4.34Å; L97-I101 WeakPolarHBondContact O-CG1 3.37Å; L97-I101 PolarHBondContact O-N 3.17Å
98	L	96.8	Very high	95.8	Very high	29 Å²	29	14.3 Å²	14.3	15%	0.152	8%	0.075	C	C	.	.	H	α-helix	trans	-58.9	-46	178.8	-179.7	141.2	0	0	0	111	L8 L9 I94 I95 L96 L100 I101 L102	L8-L98 HydrophobicContact CB-CD1 4.47Å; L8-L98 HydrophobicContact CD1-CB 4.46Å; L9-L98 HydrophobicContact CD2-CD1 3.65Å; L9-L98 HydrophobicContact CG-CD1 3.98Å; I94-L98 WeakPolarHBondContact O-CB 3.19Å; I94-L98 PolarHBondContact O-N 3.12Å; I95-L98 PolarHBondContact O-N 3.41Å; L96-L98 VanDerWaalsContact C-N 3.33Å; L96-L98 PolarHBondContact O-N 3Å; L98-L100 PolarHBondContact O-N 3.1Å; L98-I101 PolarHBondContact O-N 3.32Å; L98-L102 HydrophobicContact CD2-CD1 3.61Å; L98-L102 HydrophobicContact CG-CD1 4.28Å; L98-L102 VanDerWaalsContact O-CG 3.26Å; L98-L102 WeakPolarHBondContact O-CG 3.02Å; L98-L102 PolarHBondContact O-N 3.4Å
99	L	97.4	Very high	95.8	Very high	22 Å²	22	10 Å²	10	12%	0.115	5%	0.053	C	C	.	.	H	α-helix	trans	-62.4	-43.3	176.1	-66.9	176.7	0	0	0	111.6	I95 L96 L97 I101 L102 T103 F115 S118 P122	I95-L99 HydrophobicContact CG2-CD1 4.1Å; I95-L99 HydrophobicContact CG2-CG 4.41Å; I95-L99 WeakPolarHBondContact O-CG 3.26Å; I95-L99 PolarHBondContact O-N 3.07Å; L96-L99 PolarHBondContact O-N 3.46Å; L97-L99 VanDerWaalsContact C-N 3.33Å; L97-L99 PolarHBondContact O-N 3.42Å; L99-I101 PolarHBondContact O-N 2.82Å; L99-L102 PolarHBondContact O-N 2.97Å; L99-T103 WeakPolarHBondContact O-CG2 3.5Å; L99-T103 PolarHBondContact O-N 3Å; L99-F115 HydrophobicContact CD2-CD1 4.23Å; L99-S118 WeakPolarHBondContact CD1-O 3.45Å; L99-P122 HydrophobicContact CD1-CG 3.81Å
100	L	97	Very high	95.8	Very high	0 Å²	0	13.1 Å²	13.1	0%	0	7%	0.067	C	C	.	.	H	α-helix	trans	-63	-43.2	178.4	-70.3	171	0	0	0	112.2	L96 L97 L98 L102 T103 F104 I218 I222 M223 L226	L96-L100 HydrophobicContact CD1-CD1 4.18Å; L96-L100 HydrophobicContact CD1-CG 4.24Å; L96-L100 HydrophobicContact CG-CD1 3.95Å; L96-L100 HydrophobicContact CG-CG 4.43Å; L96-L100 WeakPolarHBondContact O-CB 3.45Å; L96-L100 VanDerWaalsContact O-CG 3.22Å; L96-L100 WeakPolarHBondContact O-CG 3.34Å; L96-L100 PolarHBondContact O-N 2.97Å; L97-L100 PolarHBondContact O-N 3.42Å; L98-L100 PolarHBondContact O-N 3.1Å; L100-L102 VanDerWaalsContact C-N 3.31Å; L100-L102 PolarHBondContact O-N 3.37Å; L100-T103 WeakPolarHBondContact CA-OG1 3.44Å; L100-T103 PolarHBondContact O-N 3.23Å; L100-T103 PolarHBondContact O-OG1 3.06Å; L100-F104 WeakPolarHBondContact O-CD2 3.45Å; L100-F104 PolarHBondContact O-N 3.18Å; L100-F104 VanDerWaalsContact O-N 3.14Å; L100-I218 HydrophobicContact CD1-CG2 4.48Å; L100-I222 HydrophobicContact CD1-CB 4.49Å; L100-I222 HydrophobicContact CD1-CD1 3.82Å; L100-I222 HydrophobicContact CD1-CG2 4.06Å; L100-I222 HydrophobicContact CD2-CG2 3.8Å; L100-I222 HydrophobicContact CG-CG2 4.45Å; L100-M223 HydrophobicContact CD2-SD 4.21Å; L100-L226 HydrophobicContact CD2-CD1 3.72Å; L100-L226 HydrophobicContact CD2-CD2 4.11Å; L100-L226 HydrophobicContact CD2-CG 4.21Å
101	I	96.1	Very high	95.8	Very high	0 Å²	0	15.3 Å²	15.3	0%	0	8%	0.077	C	C	.	.	H	α-helix	trans	-63.2	-41.1	175.9	-64.7	-178	0	0	0	110.7	M1 I4 L8 I62 L66 L97 L98 L99 T103 S105	M1-I101 HydrophobicContact CE-CG2 3.73Å; I4-I101 HydrophobicContact CG2-CD1 3.82Å; L8-I101 HydrophobicContact CD1-CD1 3.47Å; L8-I101 VanDerWaalsContact CD1-CD1 3.47Å; I62-I101 HydrophobicContact CG2-CG1 4.29Å; I62-I101 HydrophobicContact CG2-CG2 4.45Å; L66-I101 HydrophobicContact CD2-CD1 3.75Å; L66-I101 HydrophobicContact CG-CD1 4.12Å; L97-I101 HydrophobicContact CD1-CD1 4.03Å; L97-I101 HydrophobicContact CD1-CG1 4.04Å; L97-I101 HydrophobicContact CD2-CD1 4.47Å; L97-I101 HydrophobicContact CG-CD1 4.03Å; L97-I101 HydrophobicContact CG-CG1 4.34Å; L97-I101 WeakPolarHBondContact O-CG1 3.37Å; L97-I101 PolarHBondContact O-N 3.17Å; L98-I101 PolarHBondContact O-N 3.32Å; L99-I101 PolarHBondContact O-N 2.82Å; I101-T103 VanDerWaalsContact C-N 3.34Å; I101-T103 PolarHBondContact O-N 2.88Å; I101-S105 WeakPolarHBondContact O-CB 3.39Å; I101-S105 PolarHBondContact O-N 3.25Å; I101-S105 VanDerWaalsContact O-N 3.08Å; I101-S105 PolarHBondContact O-OG 2.96Å
102	L	96.3	Very high	95.8	Very high	17 Å²	17	13.8 Å²	13.8	9%	0.089	7%	0.069	C	C	.	.	H	α-helix	trans	-64.2	-36.4	175.2	-68.3	172.8	0	0	0	112.3	I5 F51 L52 L98 L99 L100 S106 F115	I5-L102 HydrophobicContact CD1-CD2 3.72Å; I5-L102 HydrophobicContact CG1-CD2 4.43Å; F51-L102 HydrophobicContact CE2-CD2 4.35Å; L52-L102 HydrophobicContact CD2-CD2 3.81Å; L98-L102 HydrophobicContact CD2-CD1 3.61Å; L98-L102 HydrophobicContact CG-CD1 4.28Å; L98-L102 VanDerWaalsContact O-CG 3.26Å; L98-L102 WeakPolarHBondContact O-CG 3.02Å; L98-L102 PolarHBondContact O-N 3.4Å; L99-L102 PolarHBondContact O-N 2.97Å; L100-L102 VanDerWaalsContact C-N 3.31Å; L100-L102 PolarHBondContact O-N 3.37Å; L102-S106 WeakPolarHBondContact O-CB 3.22Å; L102-S106 PolarHBondContact O-N 3.04Å; L102-F115 HydrophobicContact CB-CB 4.42Å; L102-F115 HydrophobicContact CB-CD1 3.93Å; L102-F115 HydrophobicContact CB-CD2 3.74Å; L102-F115 HydrophobicContact CB-CE1 4.08Å; L102-F115 HydrophobicContact CB-CE2 3.88Å; L102-F115 HydrophobicContact CB-CG 3.77Å; L102-F115 HydrophobicContact CB-CZ 4.05Å; L102-F115 HydrophobicContact CD1-CD1 4.09Å; L102-F115 HydrophobicContact CD1-CE1 3.64Å; L102-F115 HydrophobicContact CD1-CZ 3.91Å; L102-F115 HydrophobicContact CD2-CZ 4.47Å; L102-F115 HydrophobicContact CG-CE1 4.42Å; L102-F115 HydrophobicContact CG-CZ 4.37Å
103	T	96.6	Very high	95.8	Very high	0 Å²	0	13.6 Å²	13.6	0%	0	7%	0.067	C	C	.	.	H	α-helix	trans	-60.4	-55	174.6	58.7	0	0	0	0	111.8	L99 L100 I101 S105 S106 F115 F116 L226	L99-T103 WeakPolarHBondContact O-CG2 3.5Å; L99-T103 PolarHBondContact O-N 3Å; L100-T103 WeakPolarHBondContact CA-OG1 3.44Å; L100-T103 PolarHBondContact O-N 3.23Å; L100-T103 PolarHBondContact O-OG1 3.06Å; I101-T103 VanDerWaalsContact C-N 3.34Å; I101-T103 PolarHBondContact O-N 2.88Å; T103-S105 VanDerWaalsContact C-N 3.3Å; T103-S105 PolarHBondContact O-N 3.2Å; T103-S106 PolarHBondContact O-N 3.23Å; T103-S106 PolarHBondContact O-OG 3.29Å; T103-F115 HydrophobicContact CG2-CB 3.39Å; T103-F115 WeakPolarHBondContact CG2-O 3.48Å; T103-F116 HydrophobicContact CG2-CB 4.45Å; T103-L226 HydrophobicContact CG2-CD2 4.27Å; T103-L226 VanDerWaalsContact OG1-CD2 3.26Å; T103-L226 WeakPolarHBondContact OG1-CD2 3.39Å
104	F	95.1	Very high	95.8	Very high	0 Å²	0	17 Å²	17	0%	0	9%	0.085	C	C	.	.	H	α-helix	trans	-70.9	-27.1	-173.7	-66.2	-57	0	0	0	113	S58 L61 I62 L100 I222 L226 Y229	S58-F104 WeakPolarHBondContact CB-O 3.37Å; L61-F104 HydrophobicContact CB-CD1 3.76Å; L61-F104 HydrophobicContact CB-CD2 4.1Å; L61-F104 HydrophobicContact CB-CE1 3.76Å; L61-F104 HydrophobicContact CB-CE2 4.1Å; L61-F104 HydrophobicContact CB-CG 3.94Å; L61-F104 HydrophobicContact CB-CZ 3.94Å; L61-F104 HydrophobicContact CD1-CD1 3.78Å; L61-F104 HydrophobicContact CD1-CE1 3.56Å; L61-F104 HydrophobicContact CD1-CZ 4.36Å; L61-F104 HydrophobicContact CG-CD1 4.42Å; L61-F104 HydrophobicContact CG-CE1 4.2Å; I62-F104 HydrophobicContact CD1-CB 4.06Å; I62-F104 HydrophobicContact CG1-CB 3.56Å; I62-F104 HydrophobicContact CG1-CD2 4.35Å; I62-F104 HydrophobicContact CG1-CG 4.36Å; L100-F104 WeakPolarHBondContact O-CD2 3.45Å; L100-F104 PolarHBondContact O-N 3.18Å; L100-F104 VanDerWaalsContact O-N 3.14Å; F104-I222 HydrophobicContact CE2-CG2 3.66Å; F104-I222 HydrophobicContact CZ-CG2 3.72Å; F104-L226 HydrophobicContact CD1-CD2 4.31Å; F104-L226 HydrophobicContact CE1-CD2 3.55Å; F104-L226 HydrophobicContact CE1-CG 4.43Å; F104-L226 HydrophobicContact CE2-CD2 3.99Å; F104-L226 HydrophobicContact CZ-CD2 3.36Å; F104-L226 HydrophobicContact CZ-CG 4.04Å; F104-Y229 AromaticContact CD1-CD1 3.83Å; F104-Y229 HydrophobicContact CD1-CD1 3.83Å; F104-Y229 HydrophobicContact CD1-CD2 4.12Å; F104-Y229 HydrophobicContact CD1-CE1 4.18Å; F104-Y229 HydrophobicContact CD1-CE2 4.46Å; F104-Y229 AromaticContact CD1-CG 3.8Å; F104-Y229 HydrophobicContact CD1-CG 3.8Å; F104-Y229 HydrophobicContact CE1-CD1 4.23Å; F104-Y229 HydrophobicContact CE1-CG 4Å; F104-Y229 PolarHBondContact O-OH 3.31Å
105	S	94.6	Very high	95.8	Very high	0 Å²	0	18.3 Å²	18.3	0%	0	9%	0.091	C	C	.	.	H	α-helix	trans	-90.3	-6.7	179.9	59.5	0	0	0	0	114.8	L52 G53 I101 T103 M107	L52-S105 CarbonylContact C-O 3.59Å; L52-S105 VanDerWaalsContact CA-O 3.3Å; L52-S105 WeakPolarHBondContact CA-O 3.41Å; L52-S105 WeakPolarHBondContact CD2-OG 2.96Å; G53-S105 PolarHBondContact N-O 3.48Å; G53-S105 CarbonylContact O-C 3.59Å; G53-S105 VanDerWaalsContact O-CA 3.28Å; G53-S105 WeakPolarHBondContact O-CA 3.27Å; G53-S105 WeakPolarHBondContact O-CB 3.48Å; G53-S105 VanDerWaalsContact O-O 3.09Å; I101-S105 WeakPolarHBondContact O-CB 3.39Å; I101-S105 PolarHBondContact O-N 3.25Å; I101-S105 VanDerWaalsContact O-N 3.08Å; I101-S105 PolarHBondContact O-OG 2.96Å; T103-S105 VanDerWaalsContact C-N 3.3Å; T103-S105 PolarHBondContact O-N 3.2Å; S105-M107 PolarHBondContact O-N 3.49Å
106	S	94.9	Very high	95.7	Very high	0 Å²	0	15.4 Å²	15.4	0%	0	8%	0.076	C	C	.	.	B	Isolated β-bridge	trans	-69.2	126.9	-177.8	60	0	0	0	0	112.6	W45 L102 T103 F112 F170	W45-S106 WeakPolarHBondContact CH2-O 3.42Å; L102-S106 WeakPolarHBondContact O-CB 3.22Å; L102-S106 PolarHBondContact O-N 3.04Å; T103-S106 PolarHBondContact O-N 3.23Å; T103-S106 PolarHBondContact O-OG 3.29Å; S106-F112 WeakPolarHBondContact OG-CA 3.49Å; S106-F112 VanDerWaalsContact OG-CB 3.24Å; S106-F112 WeakPolarHBondContact OG-CB 3.15Å; S106-F170 WeakPolarHBondContact O-CE2 3.12Å
107	M	93	Very high	95.6	Very high	11 Å²	11	16.3 Å²	16.3	5%	0.054	8%	0.08	C	C	.	.			trans	-84.8	-25	176.5	-70.5	-77.1	-164	0	0	113.5	W45 I48 F51 S105 N169 F170 Y171	W45-M107 HydrophobicContact CB-CE 3.39Å; W45-M107 HydrophobicContact CB-SD 4.33Å; W45-M107 HydrophobicContact CD2-CE 3.42Å; W45-M107 VanDerWaalsContact CD2-CE 3.42Å; W45-M107 HydrophobicContact CD2-SD 3.24Å; W45-M107 VanDerWaalsContact CE2-SD 3.58Å; W45-M107 HydrophobicContact CE3-CE 3.29Å; W45-M107 HydrophobicContact CE3-CG 4.29Å; W45-M107 HydrophobicContact CE3-SD 3.21Å; W45-M107 HydrophobicContact CG-CE 3.59Å; W45-M107 HydrophobicContact CG-SD 3.85Å; W45-M107 HydrophobicContact CH2-SD 3.76Å; W45-M107 HydrophobicContact CZ2-SD 3.82Å; W45-M107 HydrophobicContact CZ3-CE 4.06Å; W45-M107 HydrophobicContact CZ3-CG 4.15Å; W45-M107 HydrophobicContact CZ3-SD 3.48Å; W45-M107 WeakPolarHBondContact CZ3-SD 3.48Å; I48-M107 HydrophobicContact CD1-CE 4.09Å; I48-M107 HydrophobicContact CG1-CE 3.78Å; I48-M107 HydrophobicContact CG2-CE 4.36Å; F51-M107 VanDerWaalsContact O-CB 3.31Å; F51-M107 WeakPolarHBondContact O-CB 3.33Å; F51-M107 WeakPolarHBondContact O-CG 3.45Å; F51-M107 PolarHBondContact O-N 3.48Å; S105-M107 PolarHBondContact O-N 3.49Å; M107-N169 CarbonylContact O-C 3.59Å; M107-N169 WeakPolarHBondContact O-CA 3.39Å; M107-F170 VanDerWaalsContact C-CD2 3.49Å; M107-F170 WeakPolarHBondContact O-CD2 3.34Å; M107-F170 PolarHBondContact O-N 3.21Å; M107-Y171 HydrophobicContact CE-CD2 4.48Å; M107-Y171 HydrophobicContact CE-CE2 3.72Å; M107-Y171 HydrophobicContact SD-CD2 3.78Å; M107-Y171 HydrophobicContact SD-CE2 3.54Å; M107-Y171 VanDerWaalsContact SD-CE2 3.54Å
108	S	94.2	Very high	95.6	Very high	13 Å²	13	17.7 Å²	17.7	9%	0.091	9%	0.09	C	C	.	.	B	Isolated β-bridge	trans	-103.7	134.2	-176.3	61.9	0	0	0	0	110.9	F110 M111 F112 M168	S108-F110 VanDerWaalsContact C-N 3.28Å; S108-F110 PolarHBondContact O-N 3.23Å; S108-M111 PolarHBondContact O-N 2.79Å; S108-M111 VanDerWaalsContact OG-CB 3.27Å; S108-M111 WeakPolarHBondContact OG-CB 3.44Å; S108-M111 WeakPolarHBondContact OG-CG 3.5Å; S108-F112 WeakPolarHBondContact O-CB 3.04Å; S108-F112 PolarHBondContact O-N 2.97Å; S108-M168 CarbonylContact C-O 3.59Å; S108-M168 VanDerWaalsContact CA-O 3.29Å; S108-M168 WeakPolarHBondContact CA-O 3.45Å
109	L	93.9	Very high	95.6	Very high	0 Å²	0	16.3 Å²	16.3	0%	0	8%	0.083	C	C	.	.	H	α-helix	trans	-63.7	-33.9	-174.2	-165.9	151.3	0	0	0	112.3	F112 Y113 I158 M168 F170 V234 F237	L109-F112 WeakPolarHBondContact O-CB 3.34Å; L109-Y113 PolarHBondContact O-N 3.09Å; L109-I158 HydrophobicContact CD2-CB 4.09Å; L109-I158 HydrophobicContact CD2-CD1 3.5Å; L109-I158 HydrophobicContact CD2-CG1 3.3Å; L109-I158 HydrophobicContact CD2-CG2 3.82Å; L109-M168 HydrophobicContact CB-SD 4.19Å; L109-M168 PolarHBondContact N-O 2.96Å; L109-F170 HydrophobicContact CB-CE1 3.96Å; L109-F170 HydrophobicContact CB-CZ 4.11Å; L109-F170 HydrophobicContact CD1-CD1 4.46Å; L109-F170 HydrophobicContact CD1-CE1 3.8Å; L109-F170 HydrophobicContact CG-CE1 3.92Å; L109-F170 HydrophobicContact CG-CZ 4.22Å; L109-V234 HydrophobicContact CD1-CG2 4.14Å; L109-F237 HydrophobicContact CD1-CE1 3.63Å; L109-F237 HydrophobicContact CD1-CZ 3.49Å; L109-F237 VanDerWaalsContact CD1-CZ 3.49Å
110	F	95.7	Very high	95.5	Very high	66 Å²	66	16 Å²	16	29%	0.289	8%	0.081	S	C	.	.	H	α-helix	trans	-66.1	-45.7	173.9	179.1	-103.5	0	0	0	112.8	S108 F112 Y113 L114 L155 I158 F159 M168	S108-F110 VanDerWaalsContact C-N 3.28Å; S108-F110 PolarHBondContact O-N 3.23Å; F110-F112 VanDerWaalsContact C-N 3.32Å; F110-F112 PolarHBondContact O-N 2.91Å; F110-Y113 WeakPolarHBondContact O-CB 3.48Å; F110-Y113 PolarHBondContact O-N 3.03Å; F110-L114 HydrophobicContact CD1-CD1 4Å; F110-L114 HydrophobicContact CE1-CD1 3.4Å; F110-L114 HydrophobicContact CE1-CG 4.12Å; F110-L114 HydrophobicContact CZ-CD1 3.75Å; F110-L114 HydrophobicContact CZ-CD2 4.3Å; F110-L114 HydrophobicContact CZ-CG 4.11Å; F110-L114 PolarHBondContact O-N 3.48Å; F110-L114 VanDerWaalsContact O-N 3.09Å; F110-L155 HydrophobicContact CD2-CD1 4.41Å; F110-L155 HydrophobicContact CE2-CD1 4.06Å; F110-I158 HydrophobicContact CB-CG2 4.19Å; F110-I158 HydrophobicContact CD2-CG2 4.38Å; F110-F159 HydrophobicContact CD2-CE1 4.25Å; F110-F159 AromaticContact CE2-CE1 3.93Å; F110-F159 HydrophobicContact CE2-CE1 3.93Å; F110-F159 AromaticContact CE2-CZ 3.95Å; F110-F159 HydrophobicContact CE2-CZ 3.95Å; F110-M168 HydrophobicContact CB-CG 4.48Å
111	M	95.4	Very high	95.4	Very high	47 Å²	47	20.6 Å²	20.6	23%	0.232	11%	0.105	C	C	.	.	H	α-helix	trans	-67.4	-37.7	177.7	-65.2	-60.4	-65.3	0	0	111.1	F51 S108 Y113 L114 F115	F51-M111 HydrophobicContact CE2-CE 4.3Å; F51-M111 HydrophobicContact CZ-CE 4.32Å; S108-M111 PolarHBondContact O-N 2.79Å; S108-M111 VanDerWaalsContact OG-CB 3.27Å; S108-M111 WeakPolarHBondContact OG-CB 3.44Å; S108-M111 WeakPolarHBondContact OG-CG 3.5Å; M111-Y113 VanDerWaalsContact C-N 3.32Å; M111-Y113 PolarHBondContact O-N 3.28Å; M111-L114 PolarHBondContact O-N 3.26Å; M111-L114 HydrophobicContact SD-CD1 4.14Å; M111-F115 HydrophobicContact CB-CD2 4.39Å; M111-F115 HydrophobicContact CB-CE2 4.1Å; M111-F115 HydrophobicContact CE-CE2 3.61Å; M111-F115 HydrophobicContact CE-CZ 3.54Å; M111-F115 WeakPolarHBondContact O-CD2 3.17Å; M111-F115 PolarHBondContact O-N 3.24Å
112	F	95.8	Very high	95.4	Very high	0 Å²	0	20.9 Å²	20.9	0%	0	11%	0.106	C	C	.	.	H	α-helix	trans	-53.7	-49.9	171.7	172.6	-107	0	0	0	111.3	S106 S108 L109 F110 L114 F115 F116 M154 F170 F191 Y229	S106-F112 WeakPolarHBondContact OG-CA 3.49Å; S106-F112 VanDerWaalsContact OG-CB 3.24Å; S106-F112 WeakPolarHBondContact OG-CB 3.15Å; S108-F112 WeakPolarHBondContact O-CB 3.04Å; S108-F112 PolarHBondContact O-N 2.97Å; L109-F112 WeakPolarHBondContact O-CB 3.34Å; F110-F112 VanDerWaalsContact C-N 3.32Å; F110-F112 PolarHBondContact O-N 2.91Å; F112-L114 PolarHBondContact O-N 3.4Å; F112-F115 PolarHBondContact O-N 2.84Å; F112-F116 HydrophobicContact CZ-CD2 4.22Å; F112-F116 WeakPolarHBondContact O-CB 3.28Å; F112-F116 PolarHBondContact O-N 3Å; F112-M154 HydrophobicContact CD1-CE 4.42Å; F112-M154 HydrophobicContact CE1-CE 4.38Å; F112-F170 HydrophobicContact CB-CE2 4.26Å; F112-F170 HydrophobicContact CB-CZ 4.09Å; F112-F170 HydrophobicContact CD1-CZ 4.37Å; F112-F170 HydrophobicContact CG-CZ 4.21Å; F112-F191 AromaticContact CE1-CE1 3.62Å; F112-F191 HydrophobicContact CE1-CE1 3.62Å; F112-F191 AromaticContact CE1-CZ 3.72Å; F112-F191 HydrophobicContact CE1-CZ 3.72Å; F112-F191 HydrophobicContact CZ-CE1 4.04Å; F112-F191 HydrophobicContact CZ-CZ 4.48Å; F112-Y229 HydrophobicContact CD2-CD1 4.35Å; F112-Y229 AromaticContact CD2-CE1 4Å; F112-Y229 HydrophobicContact CD2-CE1 4Å; F112-Y229 AromaticContact CE2-CD1 3.55Å; F112-Y229 HydrophobicContact CE2-CD1 3.55Å; F112-Y229 AromaticContact CE2-CE1 3.66Å; F112-Y229 HydrophobicContact CE2-CE1 3.66Å; F112-Y229 HydrophobicContact CZ-CD1 4.07Å; F112-Y229 HydrophobicContact CZ-CE1 4.47Å
113	Y	95.9	Very high	95.4	Very high	17 Å²	17	20.2 Å²	20.2	7%	0.067	10%	0.103	C	C	.	.	H	α-helix	trans	-58.9	-47	177.3	171.6	-91.5	0	0	0	112.8	L109 F110 M111 F115 F116 E117 S151 M154 L155 I158	L109-Y113 PolarHBondContact O-N 3.09Å; F110-Y113 WeakPolarHBondContact O-CB 3.48Å; F110-Y113 PolarHBondContact O-N 3.03Å; M111-Y113 VanDerWaalsContact C-N 3.32Å; M111-Y113 PolarHBondContact O-N 3.28Å; Y113-F115 PolarHBondContact O-N 2.98Å; Y113-F116 WeakPolarHBondContact O-CB 2.87Å; Y113-F116 PolarHBondContact O-N 3.19Å; Y113-E117 HydrophobicContact CD2-CG 4.35Å; Y113-E117 HydrophobicContact CE1-CG 4.26Å; Y113-E117 HydrophobicContact CE2-CG 3.84Å; Y113-E117 PolarHBondContact O-N 2.84Å; Y113-S151 VanDerWaalsContact CE2-O 3.31Å; Y113-S151 WeakPolarHBondContact CE2-O 3.21Å; Y113-S151 PolarHBondContact OH-O 3.49Å; Y113-M154 HydrophobicContact CD2-CE 4.13Å; Y113-M154 HydrophobicContact CD2-CG 4.28Å; Y113-M154 HydrophobicContact CD2-SD 3.84Å; Y113-M154 HydrophobicContact CE2-CB 4.48Å; Y113-M154 HydrophobicContact CE2-SD 4.4Å; Y113-L155 HydrophobicContact CD1-CD1 3.82Å; Y113-L155 HydrophobicContact CE1-CB 4.1Å; Y113-L155 HydrophobicContact CE1-CD1 3.6Å; Y113-L155 HydrophobicContact CE1-CG 4.26Å; Y113-L155 HydrophobicContact CE2-CB 4.24Å; Y113-I158 HydrophobicContact CD1-CD1 4.47Å; Y113-I158 HydrophobicContact CD2-CD1 4Å; Y113-I158 HydrophobicContact CG-CD1 3.74Å
114	L	96.4	Very high	95.3	Very high	73 Å²	73	21.7 Å²	21.7	38%	0.382	11%	0.111	S	C	.	.	H	α-helix	trans	-60.2	-45.5	179.5	-71.9	178.2	0	0	0	112.1	F110 M111 F112 F116 S118	F110-L114 HydrophobicContact CD1-CD1 4Å; F110-L114 HydrophobicContact CE1-CD1 3.4Å; F110-L114 HydrophobicContact CE1-CG 4.12Å; F110-L114 HydrophobicContact CZ-CD1 3.75Å; F110-L114 HydrophobicContact CZ-CD2 4.3Å; F110-L114 HydrophobicContact CZ-CG 4.11Å; F110-L114 PolarHBondContact O-N 3.48Å; F110-L114 VanDerWaalsContact O-N 3.09Å; M111-L114 PolarHBondContact O-N 3.26Å; M111-L114 HydrophobicContact SD-CD1 4.14Å; F112-L114 PolarHBondContact O-N 3.4Å; L114-F116 VanDerWaalsContact C-N 3.35Å; L114-S118 VanDerWaalsContact O-CB 3.3Å; L114-S118 WeakPolarHBondContact O-CB 3.37Å; L114-S118 PolarHBondContact O-N 3.43Å; L114-S118 PolarHBondContact O-OG 3.43Å
115	F	96.3	Very high	95.4	Very high	28 Å²	28	26.5 Å²	26.5	12%	0.123	13%	0.132	C	C	.	.	H	α-helix	trans	-69.9	-35.4	178	-62.9	-50.6	0	0	0	112.1	F51 L99 L102 T103 M111 F112 Y113 S118 S119	F51-F115 HydrophobicContact CD2-CE2 4.47Å; F51-F115 AromaticContact CE2-CE2 3.72Å; F51-F115 HydrophobicContact CE2-CE2 3.72Å; F51-F115 HydrophobicContact CE2-CZ 4.11Å; F51-F115 HydrophobicContact CZ-CE2 4.37Å; F51-F115 HydrophobicContact CZ-CZ 4.31Å; L99-F115 HydrophobicContact CD2-CD1 4.23Å; L102-F115 HydrophobicContact CB-CB 4.42Å; L102-F115 HydrophobicContact CB-CD1 3.93Å; L102-F115 HydrophobicContact CB-CD2 3.74Å; L102-F115 HydrophobicContact CB-CE1 4.08Å; L102-F115 HydrophobicContact CB-CE2 3.88Å; L102-F115 HydrophobicContact CB-CG 3.77Å; L102-F115 HydrophobicContact CB-CZ 4.05Å; L102-F115 HydrophobicContact CD1-CD1 4.09Å; L102-F115 HydrophobicContact CD1-CE1 3.64Å; L102-F115 HydrophobicContact CD1-CZ 3.91Å; L102-F115 HydrophobicContact CD2-CZ 4.47Å; L102-F115 HydrophobicContact CG-CE1 4.42Å; L102-F115 HydrophobicContact CG-CZ 4.37Å; T103-F115 HydrophobicContact CG2-CB 3.39Å; T103-F115 WeakPolarHBondContact CG2-O 3.48Å; M111-F115 HydrophobicContact CB-CD2 4.39Å; M111-F115 HydrophobicContact CB-CE2 4.1Å; M111-F115 HydrophobicContact CE-CE2 3.61Å; M111-F115 HydrophobicContact CE-CZ 3.54Å; M111-F115 WeakPolarHBondContact O-CD2 3.17Å; M111-F115 PolarHBondContact O-N 3.24Å; F112-F115 PolarHBondContact O-N 2.84Å; Y113-F115 PolarHBondContact O-N 2.98Å; F115-S118 VanDerWaalsContact CA-OG 3.23Å; F115-S118 WeakPolarHBondContact CA-OG 3.37Å; F115-S118 PolarHBondContact O-N 3.17Å; F115-S118 PolarHBondContact O-OG 3.18Å; F115-S118 VanDerWaalsContact O-OG 3.06Å; F115-S119 WeakPolarHBondContact O-CB 3.33Å; F115-S119 PolarHBondContact O-N 3.43Å
116	F	95.1	Very high	95.4	Very high	0 Å²	0	26.5 Å²	26.5	0%	0	13%	0.132	C	C	.	.	H	α-helix	trans	-63.8	-45.3	178.7	170	-96.9	0	0	0	111.8	T103 F112 Y113 L114 S119 F191 K194 L226	T103-F116 HydrophobicContact CG2-CB 4.45Å; F112-F116 HydrophobicContact CZ-CD2 4.22Å; F112-F116 WeakPolarHBondContact O-CB 3.28Å; F112-F116 PolarHBondContact O-N 3Å; Y113-F116 WeakPolarHBondContact O-CB 2.87Å; Y113-F116 PolarHBondContact O-N 3.19Å; L114-F116 VanDerWaalsContact C-N 3.35Å; F116-S119 PolarHBondContact O-OG 3.12Å; F116-F191 HydrophobicContact CE2-CD1 4.27Å; F116-F191 HydrophobicContact CE2-CE1 4.3Å; F116-F191 HydrophobicContact CZ-CD1 4.05Å; F116-F191 HydrophobicContact CZ-CE1 4.17Å; F116-K194 HydrophobicContact CE1-CG 4.38Å; F116-K194 HydrophobicContact CE2-CD 4.35Å; F116-K194 HydrophobicContact CE2-CG 3.89Å; F116-K194 HydrophobicContact CZ-CB 4.45Å; F116-K194 HydrophobicContact CZ-CD 4.04Å; F116-K194 HydrophobicContact CZ-CG 3.43Å; F116-K194 VanDerWaalsContact CZ-CG 3.43Å; F116-L226 HydrophobicContact CD2-CB 4.03Å; F116-L226 HydrophobicContact CE2-CB 4.02Å
117	E	95.1	Very high	95.4	Very high	20 Å²	20	26.6 Å²	26.6	9%	0.093	13%	0.132	C	C	.	.	H	α-helix	trans	-73.9	-39.9	175.9	-70.6	-56.6	129.7	0	0	112.2	Y113 S119 L120 L148 S151	Y113-E117 HydrophobicContact CD2-CG 4.35Å; Y113-E117 HydrophobicContact CE1-CG 4.26Å; Y113-E117 HydrophobicContact CE2-CG 3.84Å; Y113-E117 PolarHBondContact O-N 2.84Å; E117-S119 PolarHBondContact O-N 3.37Å; E117-L120 VanDerWaalsContact O-CB 3.23Å; E117-L120 WeakPolarHBondContact O-CB 3.46Å; E117-L120 PolarHBondContact O-N 3.22Å; E117-L120 VanDerWaalsContact OE2-CD1 3.29Å; E117-L120 WeakPolarHBondContact OE2-CD1 3.17Å; E117-L148 WeakPolarHBondContact OE2-CD2 3.12Å; E117-S151 WeakPolarHBondContact OE1-CB 3.2Å; E117-S151 PolarHBondContact OE1-OG 3.08Å; E117-S151 PolarHBondContact OE2-OG 2.83Å; E117-S151 VanDerWaalsContact OE2-OG 3.1Å
118	S	95.9	Very high	95.5	Very high	29 Å²	29	28.4 Å²	28.4	20%	0.203	14%	0.142	C	C	.	.	H	α-helix	trans	-64	-29.1	177.8	56.8	0	0	0	0	113.1	L99 L114 F115 L120 I121 P122	L99-S118 WeakPolarHBondContact CD1-O 3.45Å; L114-S118 VanDerWaalsContact O-CB 3.3Å; L114-S118 WeakPolarHBondContact O-CB 3.37Å; L114-S118 PolarHBondContact O-N 3.43Å; L114-S118 PolarHBondContact O-OG 3.43Å; F115-S118 VanDerWaalsContact CA-OG 3.23Å; F115-S118 WeakPolarHBondContact CA-OG 3.37Å; F115-S118 PolarHBondContact O-N 3.17Å; F115-S118 PolarHBondContact O-OG 3.18Å; F115-S118 VanDerWaalsContact O-OG 3.06Å; S118-L120 PolarHBondContact O-N 3.12Å; S118-L120 VanDerWaalsContact O-N 3.15Å; S118-I121 PolarHBondContact O-N 3.25Å; S118-P122 WeakPolarHBondContact O-CD 3.4Å
119	S	96.6	Very high	95.5	Very high	0 Å²	0	29.9 Å²	29.9	0%	0	16%	0.159	C	C	.	.	T	Hydrogen-bonded Turn	trans	-58.7	-24.6	173.8	76	0	0	0	0	113.3	F115 F116 E117 I121 P122 T123	F115-S119 WeakPolarHBondContact O-CB 3.33Å; F115-S119 PolarHBondContact O-N 3.43Å; F116-S119 PolarHBondContact O-OG 3.12Å; E117-S119 PolarHBondContact O-N 3.37Å; S119-I121 VanDerWaalsContact C-N 3.31Å; S119-I121 PolarHBondContact O-N 3Å; S119-P122 WeakPolarHBondContact O-CD 3.47Å; S119-T123 WeakPolarHBondContact O-CG2 3.44Å
120	L	95	Very high	95.5	Very high	15 Å²	15	31.5 Å²	31.5	8%	0.079	17%	0.165	C	C	.	.	H	α-helix	trans	-65.2	-34.5	175.5	-71.4	169.3	0	0	0	112.4	E117 S118 T123 L124 L143 T147 K194 M223	E117-L120 VanDerWaalsContact O-CB 3.23Å; E117-L120 WeakPolarHBondContact O-CB 3.46Å; E117-L120 PolarHBondContact O-N 3.22Å; E117-L120 VanDerWaalsContact OE2-CD1 3.29Å; E117-L120 WeakPolarHBondContact OE2-CD1 3.17Å; S118-L120 PolarHBondContact O-N 3.12Å; S118-L120 VanDerWaalsContact O-N 3.15Å; L120-T123 WeakPolarHBondContact CA-OG1 3.07Å; L120-T123 PolarHBondContact O-N 3.32Å; L120-T123 PolarHBondContact O-OG1 2.89Å; L120-L124 WeakPolarHBondContact O-CB 3.22Å; L120-L124 PolarHBondContact O-N 3.42Å; L120-L143 HydrophobicContact CD2-CG 4.44Å; L120-T147 HydrophobicContact CD1-CG2 4.46Å; L120-T147 WeakPolarHBondContact CD1-OG1 3.36Å; L120-T147 HydrophobicContact CD2-CG2 4.28Å; L120-K194 VanDerWaalsContact CG-NZ 3.29Å; L120-M223 HydrophobicContact CD2-CE 4.05Å
121	I	95.9	Very high	95.3	Very high	97 Å²	97	28.6 Å²	28.6	50%	0.497	15%	0.154	S	C	.	.	H	α-helix	trans	-63.4	-52	-173	-59.9	166.1	0	0	0	110.9	S118 S119 T123 L124 F125	S118-I121 PolarHBondContact O-N 3.25Å; S119-I121 VanDerWaalsContact C-N 3.31Å; S119-I121 PolarHBondContact O-N 3Å; I121-T123 VanDerWaalsContact C-N 3.31Å; I121-T123 PolarHBondContact O-N 3.08Å; I121-L124 PolarHBondContact O-N 3.04Å; I121-F125 HydrophobicContact CG2-CD2 4.21Å; I121-F125 HydrophobicContact CG2-CE2 3.65Å; I121-F125 HydrophobicContact CG2-CZ 4.03Å; I121-F125 PolarHBondContact O-N 3.07Å
122	P	95.9	Very high	94.9	Very high	5 Å²	5	31.1 Å²	31.1	3%	0.032	16%	0.162	C	C	.	.	H	α-helix	trans	-63.4	-34	174.5	-22.5	33.2	0	0	0	113.5	I95 L96 L99 S118 S119 L124 F125 L126	I95-P122 HydrophobicContact CG2-CG 3.89Å; L96-P122 HydrophobicContact CB-CB 3.85Å; L96-P122 HydrophobicContact CB-CG 4.38Å; L96-P122 HydrophobicContact CD1-CB 4.11Å; L96-P122 HydrophobicContact CD1-CG 4.43Å; L96-P122 HydrophobicContact CG-CB 4.43Å; L99-P122 HydrophobicContact CD1-CG 3.81Å; S118-P122 WeakPolarHBondContact O-CD 3.4Å; S119-P122 WeakPolarHBondContact O-CD 3.47Å; P122-L124 VanDerWaalsContact C-N 3.32Å; P122-L124 PolarHBondContact O-N 3.3Å; P122-F125 PolarHBondContact O-N 2.64Å; P122-L126 WeakPolarHBondContact O-CG 3.45Å; P122-L126 PolarHBondContact O-N 3.19Å
123	T	96	Very high	94.7	Very high	4 Å²	4	33.9 Å²	33.9	3%	0.025	18%	0.175	C	C	.	.	H	α-helix	trans	-65.2	-38.2	176.6	62.6	0	0	0	0	112.2	L96 S119 L120 I121 L126 I127 M223	L96-T123 HydrophobicContact CD1-CG2 3.84Å; L96-T123 HydrophobicContact CD2-CG2 4.1Å; S119-T123 WeakPolarHBondContact O-CG2 3.44Å; L120-T123 WeakPolarHBondContact CA-OG1 3.07Å; L120-T123 PolarHBondContact O-N 3.32Å; L120-T123 PolarHBondContact O-OG1 2.89Å; I121-T123 VanDerWaalsContact C-N 3.31Å; I121-T123 PolarHBondContact O-N 3.08Å; T123-L126 PolarHBondContact O-N 3.36Å; T123-I127 WeakPolarHBondContact O-CG1 3.39Å; T123-I127 PolarHBondContact O-N 3.4Å; T123-I127 VanDerWaalsContact O-N 3.1Å; T123-M223 HydrophobicContact CG2-CE 3.89Å; T123-M223 HydrophobicContact CG2-CG 4.16Å; T123-M223 HydrophobicContact CG2-SD 3.86Å
124	L	95.5	Very high	94.5	Very high	30 Å²	30	38.3 Å²	38.3	16%	0.157	21%	0.206	C	C	.	.	H	α-helix	trans	-64.2	-42.5	174.2	179.9	141.3	0	0	0	111	L120 I121 P122 L126 I127 L128 L144	L120-L124 WeakPolarHBondContact O-CB 3.22Å; L120-L124 PolarHBondContact O-N 3.42Å; I121-L124 PolarHBondContact O-N 3.04Å; P122-L124 VanDerWaalsContact C-N 3.32Å; P122-L124 PolarHBondContact O-N 3.3Å; L124-L126 VanDerWaalsContact C-N 3.32Å; L124-L126 PolarHBondContact O-N 2.91Å; L124-I127 PolarHBondContact O-N 3.3Å; L124-L128 HydrophobicContact CD2-CD1 3.49Å; L124-L128 VanDerWaalsContact CD2-CD1 3.49Å; L124-L128 HydrophobicContact CD2-CG 4.24Å; L124-L128 HydrophobicContact CG-CD1 3.95Å; L124-L128 HydrophobicContact CG-CG 4.29Å; L124-L128 WeakPolarHBondContact O-CB 3.44Å; L124-L128 WeakPolarHBondContact O-CG 3.26Å; L124-L128 PolarHBondContact O-N 3.48Å; L124-L144 HydrophobicContact CD1-CB 4.04Å; L124-L144 HydrophobicContact CD1-CD1 3.59Å; L124-L144 HydrophobicContact CD1-CG 4.45Å
125	F	95.6	Very high	94.3	Very high	102 Å²	102	40.3 Å²	40.3	45%	0.447	21%	0.213	S	C	.	.	H	α-helix	trans	-63	-35.8	173.7	-67.5	-33.6	0	0	0	113.2	I121 P122 G129	I121-F125 HydrophobicContact CG2-CD2 4.21Å; I121-F125 HydrophobicContact CG2-CE2 3.65Å; I121-F125 HydrophobicContact CG2-CZ 4.03Å; I121-F125 PolarHBondContact O-N 3.07Å; P122-F125 PolarHBondContact O-N 2.64Å; F125-G129 WeakPolarHBondContact O-CA 3.3Å; F125-G129 PolarHBondContact O-N 2.95Å
126	L	95.4	Very high	94.2	Very high	0 Å²	0	42.6 Å²	42.6	0%	0	22%	0.221	C	C	.	.	H	α-helix	trans	-62.9	-44.1	174.6	-73.5	172.5	0	0	0	112	M72 F89 L96 P122 T123 L124 W130 P212 I218	M72-L126 HydrophobicContact CE-CD1 4.39Å; F89-L126 HydrophobicContact CD2-CD2 3.87Å; F89-L126 HydrophobicContact CE2-CD2 3.63Å; L96-L126 HydrophobicContact CD2-CD1 3.91Å; P122-L126 WeakPolarHBondContact O-CG 3.45Å; P122-L126 PolarHBondContact O-N 3.19Å; T123-L126 PolarHBondContact O-N 3.36Å; L124-L126 VanDerWaalsContact C-N 3.32Å; L124-L126 PolarHBondContact O-N 2.91Å; L126-W130 HydrophobicContact CD2-CE3 4.07Å; L126-W130 HydrophobicContact CD2-CZ3 4.03Å; L126-W130 PolarHBondContact O-N 3.03Å; L126-P212 WeakPolarHBondContact O-CD 3.29Å; L126-P212 WeakPolarHBondContact O-CG 3.09Å; L126-I218 HydrophobicContact CD1-CD1 3.6Å
127	I	95.6	Very high	94.2	Very high	1 Å²	1	47.8 Å²	47.8	1%	0.005	25%	0.248	C	C	.	.	H	α-helix	trans	-68	-50.6	179.4	-62.8	167.1	0	0	0	110.9	T123 L124 G131 R136 L143 A211 L219	T123-I127 WeakPolarHBondContact O-CG1 3.39Å; T123-I127 PolarHBondContact O-N 3.4Å; T123-I127 VanDerWaalsContact O-N 3.1Å; L124-I127 PolarHBondContact O-N 3.3Å; I127-G131 WeakPolarHBondContact O-CA 3.11Å; I127-G131 PolarHBondContact O-N 3.22Å; I127-R136 HydrophobicContact CG2-CB 4.32Å; I127-L143 HydrophobicContact CD1-CD2 3.75Å; I127-A211 HydrophobicContact CG1-CB 4.06Å; I127-L219 HydrophobicContact CD1-CD1 4.34Å
128	L	94.9	Very high	94.2	Very high	49 Å²	49	51.2 Å²	51.2	26%	0.257	26%	0.264	S	S	.	.	H	α-helix	trans	-71.3	-37.7	-175.8	-65.3	-173.7	0	0	0	113	L124 R136 L137	L124-L128 HydrophobicContact CD2-CD1 3.49Å; L124-L128 VanDerWaalsContact CD2-CD1 3.49Å; L124-L128 HydrophobicContact CD2-CG 4.24Å; L124-L128 HydrophobicContact CG-CD1 3.95Å; L124-L128 HydrophobicContact CG-CG 4.29Å; L124-L128 WeakPolarHBondContact O-CB 3.44Å; L124-L128 WeakPolarHBondContact O-CG 3.26Å; L124-L128 PolarHBondContact O-N 3.48Å; L128-R136 PolarHBondContact O-NE 3.33Å; L128-R136 PolarHBondContact O-NH1 3.5Å; L128-R136 PolarHBondContact O-NH2 3.12Å; L128-L137 HydrophobicContact CD2-CD2 3.84Å; L128-L137 HydrophobicContact CD2-CG 4.47Å
129	G	92.5	Very high	94.1	Very high	44 Å²	44	50 Å²	50	45%	0.454	26%	0.255	S	S	.	.	H	α-helix	trans	-72.2	-55.1	-177.6	0	0	0	0	0	112.6	F125 R136	F125-G129 WeakPolarHBondContact O-CA 3.3Å; F125-G129 PolarHBondContact O-N 2.95Å; G129-R136 PolarHBondContact O-NH1 2.98Å
130	W	94	Very high	94	Very high	35 Å²	35	50 Å²	50	13%	0.133	26%	0.256	C	S	.	.	H	α-helix	trans	-113.6	6.4	-168.6	-59.5	-91.3	0	0	0	114.6	I79 N84 L88 F89 N92 L126 P212	I79-W130 HydrophobicContact CD1-CB 4.33Å; I79-W130 HydrophobicContact CD1-CG 4.05Å; N84-W130 PolarHBondContact O-NE1 3.36Å; N84-W130 VanDerWaalsContact O-NE1 3.07Å; L88-W130 HydrophobicContact CB-CH2 4.46Å; L88-W130 HydrophobicContact CB-CZ2 4.38Å; F89-W130 VanDerWaalsContact CA-CH2 3.49Å; F89-W130 HydrophobicContact CB-CH2 3.95Å; F89-W130 HydrophobicContact CB-CZ2 3.37Å; F89-W130 AromaticContact CD2-CD2 3.66Å; F89-W130 HydrophobicContact CD2-CD2 3.66Å; F89-W130 AromaticContact CD2-CE2 3.67Å; F89-W130 AromaticContact CD2-CE3 3.89Å; F89-W130 HydrophobicContact CD2-CE3 3.89Å; F89-W130 HydrophobicContact CD2-CG 4.21Å; F89-W130 HydrophobicContact CD2-CH2 4.13Å; F89-W130 AromaticContact CD2-CZ2 3.93Å; F89-W130 HydrophobicContact CD2-CZ2 3.93Å; F89-W130 HydrophobicContact CD2-CZ3 4.11Å; F89-W130 HydrophobicContact CE2-CD2 4.4Å; F89-W130 HydrophobicContact CG-CZ2 4.14Å; N92-W130 WeakPolarHBondContact ND2-CH2 2.83Å; N92-W130 WeakPolarHBondContact ND2-CZ3 3.42Å; L126-W130 HydrophobicContact CD2-CE3 4.07Å; L126-W130 HydrophobicContact CD2-CZ3 4.03Å; L126-W130 PolarHBondContact O-N 3.03Å; W130-P212 HydrophobicContact CB-CB 4.12Å; W130-P212 HydrophobicContact CB-CG 4.05Å
131	G	92.1	Very high	94	Very high	5 Å²	5	53.9 Å²	53.9	5%	0.052	28%	0.276	C	S	.	.			trans	-64.1	148.3	172.3	0	0	0	0	0	112.4	I127 R136 E210	I127-G131 WeakPolarHBondContact O-CA 3.11Å; I127-G131 PolarHBondContact O-N 3.22Å; G131-R136 WeakPolarHBondContact O-CD 3.23Å; G131-R136 PolarHBondContact O-NH1 2.96Å; G131-E210 VanDerWaalsContact CA-O 3.28Å; G131-E210 WeakPolarHBondContact CA-O 3.28Å
132	Y	86.6	Confident	93.9	Very high	99 Å²	99	52.8 Å²	52.8	39%	0.388	27%	0.266	S	S	.	.	S	Bend	trans	-83.5	-38.2	-168.8	-62.7	-79	0	0	0	114.4	Y322	Y132-Y322 HydrophobicContact CD1-CE1 4.21Å; Y132-Y322 HydrophobicContact CD2-CE1 4.33Å; Y132-Y322 HydrophobicContact CE1-CE1 4.07Å; Y132-Y322 HydrophobicContact CE2-CE1 4.2Å; Y132-Y322 HydrophobicContact CG-CE1 4.34Å
133	Q	91.4	Very high	93.7	Very high	59 Å²	59	52.8 Å²	52.8	28%	0.276	27%	0.266	S	S	.	.	S	Bend	trans	-109.2	160.5	-171.4	-36.3	-168.9	-42.8	0	0	111.8	E135 R136 E210 R328	Q133-E135 PolarHBondContact O-N 3.2Å; Q133-R136 WeakPolarHBondContact O-CB 3.36Å; Q133-R136 VanDerWaalsContact O-CD 3.29Å; Q133-R136 WeakPolarHBondContact O-CD 3.4Å; Q133-R136 WeakPolarHBondContact O-CG 3.11Å; Q133-R136 PolarHBondContact O-N 3.48Å; Q133-E210 WeakPolarHBondContact CB-OE2 2.98Å; Q133-E210 VanDerWaalsContact CG-OE2 3.32Å; Q133-E210 WeakPolarHBondContact CG-OE2 3.21Å; Q133-E210 PolarHBondContact OE1-OE1 2.96Å; Q133-R328 VanDerWaalsContact CD-CZ 3.41Å; Q133-R328 VanDerWaalsContact CD-NH1 3.28Å; Q133-R328 VanDerWaalsContact NE2-CZ 3.3Å
134	P	92	Very high	93.6	Very high	110 Å²	110	55.2 Å²	55.2	71%	0.714	28%	0.278	S	S	*	.	T	Hydrogen-bonded Turn	trans	-61.6	-27.8	179.5	23.6	-35.3	0	0	0	113.7	R136 L137	P134-R136 PolarHBondContact O-N 3.43Å; P134-L137 PolarHBondContact O-N 3.14Å
135	E	92.9	Very high	93.6	Very high	114 Å²	114	59 Å²	59	53%	0.533	29%	0.294	S	S	.	.	T	Hydrogen-bonded Turn	trans	-61.6	-13.2	178.4	-63.5	-178.5	-167.7	0	0	113.4	Q133 L137 Q138 A139 E210	Q133-E135 PolarHBondContact O-N 3.2Å; E135-L137 PolarHBondContact O-N 3.26Å; E135-L137 VanDerWaalsContact O-N 3.14Å; E135-Q138 WeakPolarHBondContact O-CB 3.35Å; E135-Q138 PolarHBondContact O-N 3.21Å; E135-A139 PolarHBondContact O-N 3.29Å; E135-E210 HydrophobicContact CB-CG 4.07Å
136	R	94.3	Very high	93.4	Very high	77 Å²	77	57.5 Å²	57.5	29%	0.291	29%	0.285	S	S	.	.	H	α-helix	trans	-52.7	-33.1	173.4	72.9	-170.2	179.5	161.4	10.2	113.7	I127 L128 G129 G131 Q133 P134 G140 E210	I127-R136 HydrophobicContact CG2-CB 4.32Å; L128-R136 PolarHBondContact O-NE 3.33Å; L128-R136 PolarHBondContact O-NH1 3.5Å; L128-R136 PolarHBondContact O-NH2 3.12Å; G129-R136 PolarHBondContact O-NH1 2.98Å; G131-R136 WeakPolarHBondContact O-CD 3.23Å; G131-R136 PolarHBondContact O-NH1 2.96Å; Q133-R136 WeakPolarHBondContact O-CB 3.36Å; Q133-R136 VanDerWaalsContact O-CD 3.29Å; Q133-R136 WeakPolarHBondContact O-CD 3.4Å; Q133-R136 WeakPolarHBondContact O-CG 3.11Å; Q133-R136 PolarHBondContact O-N 3.48Å; P134-R136 PolarHBondContact O-N 3.43Å; R136-G140 PolarHBondContact O-N 3.37Å; R136-E210 HydrophobicContact CB-CB 4.2Å
137	L	93.8	Very high	93.3	Very high	109 Å²	109	57.7 Å²	57.7	57%	0.571	29%	0.287	S	S	*	.	H	α-helix	trans	-65.5	-48.1	176.1	-73.5	165.2	0	0	0	110.8	L128 P134 E135 A139 G140 L141	L128-L137 HydrophobicContact CD2-CD2 3.84Å; L128-L137 HydrophobicContact CD2-CG 4.47Å; P134-L137 PolarHBondContact O-N 3.14Å; E135-L137 PolarHBondContact O-N 3.26Å; E135-L137 VanDerWaalsContact O-N 3.14Å; L137-A139 PolarHBondContact O-N 2.93Å; L137-G140 PolarHBondContact O-N 3.29Å; L137-L141 WeakPolarHBondContact O-CG 3.21Å; L137-L141 PolarHBondContact O-N 2.87Å
138	Q	95.6	Very high	93.2	Very high	92 Å²	92	60.7 Å²	60.7	43%	0.43	30%	0.303	S	S	.	.	H	α-helix	trans	-64.7	-41.4	178.3	-165.7	-172.6	-3.9	0	0	111.1	E135 L141 Y142	E135-Q138 WeakPolarHBondContact O-CB 3.35Å; E135-Q138 PolarHBondContact O-N 3.21Å; Q138-L141 PolarHBondContact O-N 3.46Å; Q138-Y142 HydrophobicContact CG-CD2 4.05Å; Q138-Y142 HydrophobicContact CG-CE2 3.49Å; Q138-Y142 VanDerWaalsContact CG-CE2 3.49Å; Q138-Y142 PolarHBondContact NE2-OH 2.92Å; Q138-Y142 WeakPolarHBondContact O-CD2 3.35Å; Q138-Y142 PolarHBondContact O-N 3.48Å
139	A	94.5	Very high	93.1	Very high	2 Å²	2	64 Å²	64	2%	0.017	32%	0.319	C	S	.	.	H	α-helix	trans	-62.5	-43.2	175.6	0	0	0	0	0	112.3	E135 L137 Y142 L143 K206 E210	E135-A139 PolarHBondContact O-N 3.29Å; L137-A139 PolarHBondContact O-N 2.93Å; A139-Y142 PolarHBondContact O-N 3.13Å; A139-L143 PolarHBondContact O-N 3.21Å; A139-K206 HydrophobicContact CB-CB 4.21Å; A139-E210 HydrophobicContact CB-CB 4.04Å; A139-E210 HydrophobicContact CB-CG 4.18Å
140	G	94.3	Very high	93.1	Very high	1 Å²	1	63.6 Å²	63.6	1%	0.01	31%	0.309	C	S	.	.	H	α-helix	trans	-61.8	-40.9	175.3	0	0	0	0	0	112.8	R136 L137 L143 L144	R136-G140 PolarHBondContact O-N 3.37Å; L137-G140 PolarHBondContact O-N 3.29Å; G140-L143 PolarHBondContact O-N 3.08Å; G140-L144 WeakPolarHBondContact O-CB 3.49Å; G140-L144 PolarHBondContact O-N 3.4Å; G140-L144 VanDerWaalsContact O-N 3.07Å
141	L	94.5	Very high	93	Very high	97 Å²	97	62 Å²	62	51%	0.508	30%	0.303	S	S	.	.	H	α-helix	trans	-65.6	-42.9	175.2	-68.8	173.1	0	0	0	112	L137 Q138 L144 F145	L137-L141 WeakPolarHBondContact O-CG 3.21Å; L137-L141 PolarHBondContact O-N 2.87Å; Q138-L141 PolarHBondContact O-N 3.46Å; L141-L144 PolarHBondContact O-N 3.4Å; L141-F145 HydrophobicContact CB-CD2 4.38Å; L141-F145 HydrophobicContact CB-CE2 4.48Å; L141-F145 HydrophobicContact CD2-CE2 4.11Å; L141-F145 VanDerWaalsContact O-CD2 3.23Å; L141-F145 WeakPolarHBondContact O-CD2 3.43Å; L141-F145 PolarHBondContact O-N 3.15Å
142	Y	93.9	Very high	93.1	Very high	74 Å²	74	66.3 Å²	66.3	29%	0.29	32%	0.324	S	S	.	.	H	α-helix	trans	-60.2	-48.5	174.3	-73.6	-52	0	0	0	111.5	Q138 A139 L144 F145 Y146 K206	Q138-Y142 HydrophobicContact CG-CD2 4.05Å; Q138-Y142 HydrophobicContact CG-CE2 3.49Å; Q138-Y142 VanDerWaalsContact CG-CE2 3.49Å; Q138-Y142 PolarHBondContact NE2-OH 2.92Å; Q138-Y142 WeakPolarHBondContact O-CD2 3.35Å; Q138-Y142 PolarHBondContact O-N 3.48Å; A139-Y142 PolarHBondContact O-N 3.13Å; Y142-L144 VanDerWaalsContact C-N 3.29Å; Y142-L144 PolarHBondContact O-N 2.97Å; Y142-F145 PolarHBondContact O-N 2.92Å; Y142-Y146 HydrophobicContact CD1-CD2 4.33Å; Y142-Y146 AromaticContact CD1-CE2 3.79Å; Y142-Y146 HydrophobicContact CD1-CE2 3.79Å; Y142-Y146 HydrophobicContact CG-CE2 4.43Å; Y142-Y146 WeakPolarHBondContact O-CB 3.48Å; Y142-Y146 WeakPolarHBondContact O-CD2 3.33Å; Y142-Y146 PolarHBondContact O-N 2.84Å; Y142-K206 HydrophobicContact CD2-CD 3.56Å; Y142-K206 HydrophobicContact CE2-CD 3.56Å
143	L	92.7	Very high	93.5	Very high	4 Å²	4	63.9 Å²	63.9	2%	0.021	32%	0.32	C	S	.	.	H	α-helix	trans	-52.4	-50.7	176.8	179	74.3	0	0	0	111	L120 I127 A139 G140 T147 W203 L219	L120-L143 HydrophobicContact CD2-CG 4.44Å; I127-L143 HydrophobicContact CD1-CD2 3.75Å; A139-L143 PolarHBondContact O-N 3.21Å; G140-L143 PolarHBondContact O-N 3.08Å; L143-T147 WeakPolarHBondContact O-CG2 3.41Å; L143-T147 PolarHBondContact O-N 3.15Å; L143-T147 PolarHBondContact O-OG1 2.81Å; L143-W203 HydrophobicContact CD1-CD2 4.31Å; L143-W203 HydrophobicContact CD1-CE3 3.38Å; L143-W203 HydrophobicContact CD1-CH2 4.25Å; L143-W203 HydrophobicContact CD1-CZ3 3.34Å; L143-L219 HydrophobicContact CD1-CD2 4.49Å
144	L	94	Very high	93.6	Very high	56 Å²	56	61.1 Å²	61.1	29%	0.293	31%	0.307	S	S	.	.	H	α-helix	trans	-65	-48.8	-175.8	-179.8	140.1	0	0	0	112.8	L124 G140 L141 Y142 T147 L148	L124-L144 HydrophobicContact CD1-CB 4.04Å; L124-L144 HydrophobicContact CD1-CD1 3.59Å; L124-L144 HydrophobicContact CD1-CG 4.45Å; G140-L144 WeakPolarHBondContact O-CB 3.49Å; G140-L144 PolarHBondContact O-N 3.4Å; G140-L144 VanDerWaalsContact O-N 3.07Å; L141-L144 PolarHBondContact O-N 3.4Å; Y142-L144 VanDerWaalsContact C-N 3.29Å; Y142-L144 PolarHBondContact O-N 2.97Å; L144-T147 PolarHBondContact O-N 3.19Å; L144-T147 PolarHBondContact O-OG1 3.39Å; L144-L148 HydrophobicContact CD1-CD1 4.14Å; L144-L148 HydrophobicContact CD2-CD1 3.54Å; L144-L148 HydrophobicContact CG-CD1 3.53Å; L144-L148 HydrophobicContact CG-CG 4.27Å; L144-L148 VanDerWaalsContact O-CB 3.28Å; L144-L148 WeakPolarHBondContact O-CB 3.3Å; L144-L148 VanDerWaalsContact O-CG 3.31Å; L144-L148 WeakPolarHBondContact O-CG 3.32Å; L144-L148 PolarHBondContact O-N 3.28Å
145	F	94.4	Very high	93.8	Very high	110 Å²	110	57.7 Å²	57.7	48%	0.482	28%	0.283	S	S	.	.	H	α-helix	trans	-72.2	-39.8	-175.3	-77.6	-63.3	0	0	0	113.1	L141 Y142 T147 L149	L141-F145 HydrophobicContact CB-CD2 4.38Å; L141-F145 HydrophobicContact CB-CE2 4.48Å; L141-F145 HydrophobicContact CD2-CE2 4.11Å; L141-F145 VanDerWaalsContact O-CD2 3.23Å; L141-F145 WeakPolarHBondContact O-CD2 3.43Å; L141-F145 PolarHBondContact O-N 3.15Å; Y142-F145 PolarHBondContact O-N 2.92Å; F145-T147 VanDerWaalsContact C-N 3.26Å; F145-T147 PolarHBondContact O-N 3.11Å; F145-L149 VanDerWaalsContact O-CB 3.32Å; F145-L149 WeakPolarHBondContact O-CB 3.41Å; F145-L149 VanDerWaalsContact O-CG 3.26Å; F145-L149 WeakPolarHBondContact O-CG 3.22Å; F145-L149 PolarHBondContact O-N 2.65Å; F145-L149 VanDerWaalsContact O-N 3.16Å
146	Y	92.7	Very high	93.9	Very high	69 Å²	69	57.9 Å²	57.9	27%	0.271	29%	0.287	S	S	.	.	H	α-helix	trans	-60.1	-41.3	177.1	-86.8	-96.2	0	0	0	110.8	Y142 V200 W203	Y142-Y146 HydrophobicContact CD1-CD2 4.33Å; Y142-Y146 AromaticContact CD1-CE2 3.79Å; Y142-Y146 HydrophobicContact CD1-CE2 3.79Å; Y142-Y146 HydrophobicContact CG-CE2 4.43Å; Y142-Y146 WeakPolarHBondContact O-CB 3.48Å; Y142-Y146 WeakPolarHBondContact O-CD2 3.33Å; Y142-Y146 PolarHBondContact O-N 2.84Å; Y146-V200 HydrophobicContact CD1-CG1 3.57Å; Y146-V200 HydrophobicContact CE1-CG1 3.83Å; Y146-W203 HydrophobicContact CD2-CB 4.13Å; Y146-W203 HydrophobicContact CG-CB 4.21Å; Y146-W203 HydrophobicContact CG-CG 4.47Å
147	T	92.9	Very high	93.9	Very high	4 Å²	4	54.4 Å²	54.4	3%	0.025	28%	0.275	C	S	.	.	H	α-helix	trans	-79.4	-45.6	-178	58.7	0	0	0	0	112.8	L120 L143 L144 F145 V150 S151 K194	L120-T147 HydrophobicContact CD1-CG2 4.46Å; L120-T147 WeakPolarHBondContact CD1-OG1 3.36Å; L120-T147 HydrophobicContact CD2-CG2 4.28Å; L143-T147 WeakPolarHBondContact O-CG2 3.41Å; L143-T147 PolarHBondContact O-N 3.15Å; L143-T147 PolarHBondContact O-OG1 2.81Å; L144-T147 PolarHBondContact O-N 3.19Å; L144-T147 PolarHBondContact O-OG1 3.39Å; F145-T147 VanDerWaalsContact C-N 3.26Å; F145-T147 PolarHBondContact O-N 3.11Å; T147-V150 PolarHBondContact O-N 3.03Å; T147-S151 VanDerWaalsContact O-CB 3.27Å; T147-S151 WeakPolarHBondContact O-CB 3.12Å; T147-S151 PolarHBondContact O-N 3.45Å; T147-S151 PolarHBondContact O-OG 3.47Å; T147-S151 VanDerWaalsContact O-OG 3.09Å; T147-K194 HydrophobicContact CG2-CD 3.81Å; T147-K194 VanDerWaalsContact CG2-CE 3.49Å
148	L	92.9	Very high	94	Very high	65 Å²	65	49.2 Å²	49.2	34%	0.34	25%	0.247	S	C	.	.	H	α-helix	trans	-66.4	-41.5	-176	-74.5	178.5	0	0	0	112.9	E117 L144 V150 S151 L152	E117-L148 WeakPolarHBondContact OE2-CD2 3.12Å; L144-L148 HydrophobicContact CD1-CD1 4.14Å; L144-L148 HydrophobicContact CD2-CD1 3.54Å; L144-L148 HydrophobicContact CG-CD1 3.53Å; L144-L148 HydrophobicContact CG-CG 4.27Å; L144-L148 VanDerWaalsContact O-CB 3.28Å; L144-L148 WeakPolarHBondContact O-CB 3.3Å; L144-L148 VanDerWaalsContact O-CG 3.31Å; L144-L148 WeakPolarHBondContact O-CG 3.32Å; L144-L148 PolarHBondContact O-N 3.28Å; L148-V150 PolarHBondContact O-N 3.01Å; L148-S151 WeakPolarHBondContact CA-OG 3.08Å; L148-S151 PolarHBondContact O-N 3.46Å; L148-S151 PolarHBondContact O-OG 3.12Å; L148-L152 WeakPolarHBondContact O-CG 3.42Å; L148-L152 PolarHBondContact O-N 3.46Å; L148-L152 VanDerWaalsContact O-N 3.13Å
149	L	93	Very high	93.9	Very high	117 Å²	117	49.8 Å²	49.8	61%	0.613	25%	0.249	S	C	*	.	H	α-helix	trans	-63.2	-31	-177.6	-72.1	174.1	0	0	0	112.1	F145 P153	F145-L149 VanDerWaalsContact O-CB 3.32Å; F145-L149 WeakPolarHBondContact O-CB 3.41Å; F145-L149 VanDerWaalsContact O-CG 3.26Å; F145-L149 WeakPolarHBondContact O-CG 3.22Å; F145-L149 PolarHBondContact O-N 2.65Å; F145-L149 VanDerWaalsContact O-N 3.16Å; L149-P153 WeakPolarHBondContact O-CD 3.32Å
150	V	92.1	Very high	93.9	Very high	37 Å²	37	53.8 Å²	53.8	22%	0.224	26%	0.264	C	S	.	.	H	α-helix	trans	-95.5	-25.3	-177.8	-168.7	0	0	0	0	112.2	T147 L148 P153 C189 V193	T147-V150 PolarHBondContact O-N 3.03Å; L148-V150 PolarHBondContact O-N 3.01Å; V150-P153 WeakPolarHBondContact O-CD 3.23Å; V150-C189 HydrophobicContact CG1-CB 3.48Å; V150-C189 VanDerWaalsContact CG1-CB 3.48Å; V150-C189 WeakPolarHBondContact CG1-O 3.46Å; V150-V193 HydrophobicContact CB-CG2 3.93Å; V150-V193 HydrophobicContact CG1-CG2 3.94Å; V150-V193 HydrophobicContact CG2-CG2 3.76Å
151	S	93.2	Very high	93.8	Very high	1 Å²	1	53.8 Å²	53.8	1%	0.007	26%	0.263	C	S	.	.	H	α-helix	trans	-74.6	-30.8	174.6	68.4	0	0	0	0	113.4	Y113 E117 T147 L148 M154 L155	Y113-S151 VanDerWaalsContact CE2-O 3.31Å; Y113-S151 WeakPolarHBondContact CE2-O 3.21Å; Y113-S151 PolarHBondContact OH-O 3.49Å; E117-S151 WeakPolarHBondContact OE1-CB 3.2Å; E117-S151 PolarHBondContact OE1-OG 3.08Å; E117-S151 PolarHBondContact OE2-OG 2.83Å; E117-S151 VanDerWaalsContact OE2-OG 3.1Å; T147-S151 VanDerWaalsContact O-CB 3.27Å; T147-S151 WeakPolarHBondContact O-CB 3.12Å; T147-S151 PolarHBondContact O-N 3.45Å; T147-S151 PolarHBondContact O-OG 3.47Å; T147-S151 VanDerWaalsContact O-OG 3.09Å; L148-S151 WeakPolarHBondContact CA-OG 3.08Å; L148-S151 PolarHBondContact O-N 3.46Å; L148-S151 PolarHBondContact O-OG 3.12Å; S151-M154 WeakPolarHBondContact O-CA 3.37Å; S151-M154 VanDerWaalsContact O-CB 3.23Å; S151-M154 WeakPolarHBondContact O-CB 3.23Å; S151-M154 PolarHBondContact O-N 3.27Å; S151-L155 PolarHBondContact O-N 2.86Å; S151-L155 VanDerWaalsContact O-N 3.15Å
152	L	93.3	Very high	93.7	Very high	95 Å²	95	52.9 Å²	52.9	50%	0.497	26%	0.258	S	S	.	.	H	α-helix	trans	-59.4	-44.6	176	-72.5	171.5	0	0	0	113.7	L148 M154 L155 I156	L148-L152 WeakPolarHBondContact O-CG 3.42Å; L148-L152 PolarHBondContact O-N 3.46Å; L148-L152 VanDerWaalsContact O-N 3.13Å; L152-M154 VanDerWaalsContact C-N 3.26Å; L152-M154 PolarHBondContact O-N 3.41Å; L152-L155 WeakPolarHBondContact O-CB 3.36Å; L152-L155 PolarHBondContact O-N 3.03Å; L152-I156 PolarHBondContact O-N 3.47Å
153	P	94.9	Very high	93.7	Very high	49 Å²	49	56 Å²	56	32%	0.318	28%	0.279	S	S	.	.	H	α-helix	trans	-56.1	-36.3	169.3	-28.9	33.6	0	0	0	114.4	L149 V150 I156 G157	L149-P153 WeakPolarHBondContact O-CD 3.32Å; V150-P153 WeakPolarHBondContact O-CD 3.23Å; P153-I156 PolarHBondContact O-N 2.86Å; P153-G157 PolarHBondContact O-N 3.41Å; P153-G157 VanDerWaalsContact O-N 3.12Å
154	M	94.7	Very high	93.5	Very high	0 Å²	0	61.4 Å²	61.4	0%	0	30%	0.303	C	S	.	.	H	α-helix	trans	-59.6	-48.4	175.4	179.7	-172.9	168.6	0	0	109.6	F112 Y113 S151 L152 I156 G157 I158 C186 L187 A190 F191	F112-M154 HydrophobicContact CD1-CE 4.42Å; F112-M154 HydrophobicContact CE1-CE 4.38Å; Y113-M154 HydrophobicContact CD2-CE 4.13Å; Y113-M154 HydrophobicContact CD2-CG 4.28Å; Y113-M154 HydrophobicContact CD2-SD 3.84Å; Y113-M154 HydrophobicContact CE2-CB 4.48Å; Y113-M154 HydrophobicContact CE2-SD 4.4Å; S151-M154 WeakPolarHBondContact O-CA 3.37Å; S151-M154 VanDerWaalsContact O-CB 3.23Å; S151-M154 WeakPolarHBondContact O-CB 3.23Å; S151-M154 PolarHBondContact O-N 3.27Å; L152-M154 VanDerWaalsContact C-N 3.26Å; L152-M154 PolarHBondContact O-N 3.41Å; M154-I156 VanDerWaalsContact C-N 3.28Å; M154-I156 PolarHBondContact O-N 2.61Å; M154-G157 CarbonylContact O-C 3.37Å; M154-G157 WeakPolarHBondContact O-CA 3.41Å; M154-G157 PolarHBondContact O-N 3.45Å; M154-I158 HydrophobicContact CE-CD1 4.16Å; M154-I158 HydrophobicContact CG-CD1 4.27Å; M154-I158 HydrophobicContact CG-CG1 4.4Å; M154-I158 VanDerWaalsContact O-CG1 3.31Å; M154-I158 WeakPolarHBondContact O-CG1 3.41Å; M154-I158 PolarHBondContact O-N 3.41Å; M154-C186 VanDerWaalsContact CA-O 3.25Å; M154-C186 WeakPolarHBondContact CA-O 3.37Å; M154-C186 WeakPolarHBondContact CB-O 3.38Å; M154-C186 PolarHBondContact N-O 3.04Å; M154-L187 HydrophobicContact CG-CD2 4.08Å; M154-A190 HydrophobicContact CB-CB 3.98Å; M154-A190 HydrophobicContact CG-CB 4.43Å; M154-A190 HydrophobicContact SD-CB 3.79Å; M154-F191 HydrophobicContact CE-CE1 4.07Å; M154-F191 HydrophobicContact CE-CE2 4.18Å; M154-F191 HydrophobicContact CE-CZ 3.42Å; M154-F191 VanDerWaalsContact CE-CZ 3.42Å; M154-F191 HydrophobicContact SD-CE1 4.26Å; M154-F191 HydrophobicContact SD-CE2 4.46Å; M154-F191 HydrophobicContact SD-CZ 3.94Å
155	L	95.4	Very high	93.3	Very high	39 Å²	39	60.2 Å²	60.2	20%	0.204	30%	0.296	C	S	.	.	H	α-helix	trans	-53	-42.5	177.4	-176.7	72.1	0	0	0	112.9	F110 Y113 S151 L152 G157 I158 F159	F110-L155 HydrophobicContact CD2-CD1 4.41Å; F110-L155 HydrophobicContact CE2-CD1 4.06Å; Y113-L155 HydrophobicContact CD1-CD1 3.82Å; Y113-L155 HydrophobicContact CE1-CB 4.1Å; Y113-L155 HydrophobicContact CE1-CD1 3.6Å; Y113-L155 HydrophobicContact CE1-CG 4.26Å; Y113-L155 HydrophobicContact CE2-CB 4.24Å; S151-L155 PolarHBondContact O-N 2.86Å; S151-L155 VanDerWaalsContact O-N 3.15Å; L152-L155 WeakPolarHBondContact O-CB 3.36Å; L152-L155 PolarHBondContact O-N 3.03Å; L155-G157 VanDerWaalsContact C-N 3.33Å; L155-G157 PolarHBondContact O-N 3.04Å; L155-I158 WeakPolarHBondContact O-CB 3.11Å; L155-I158 PolarHBondContact O-N 3.28Å; L155-F159 HydrophobicContact CD1-CD2 4.48Å; L155-F159 HydrophobicContact CD1-CE2 3.8Å; L155-F159 HydrophobicContact CD1-CZ 3.95Å; L155-F159 HydrophobicContact CD2-CE2 3.98Å; L155-F159 HydrophobicContact CG-CD2 4.13Å; L155-F159 HydrophobicContact CG-CE2 3.65Å; L155-F159 HydrophobicContact CG-CZ 4.31Å; L155-F159 WeakPolarHBondContact O-CD2 3.27Å; L155-F159 PolarHBondContact O-N 3.21Å
156	I	95.2	Very high	93	Very high	118 Å²	118	57.5 Å²	57.5	61%	0.605	30%	0.299	S	S	*	.	H	α-helix	trans	-62.1	-43.8	176.3	-60.1	170.7	0	0	0	110.4	L152 P153 M154 I158 F159 Y160	L152-I156 PolarHBondContact O-N 3.47Å; P153-I156 PolarHBondContact O-N 2.86Å; M154-I156 VanDerWaalsContact C-N 3.28Å; M154-I156 PolarHBondContact O-N 2.61Å; I156-I158 VanDerWaalsContact C-N 3.31Å; I156-I158 PolarHBondContact O-N 3.09Å; I156-F159 PolarHBondContact O-N 3.31Å; I156-Y160 PolarHBondContact O-N 3.21Å
157	G	94.6	Very high	92.9	Very high	4 Å²	4	55.4 Å²	55.4	4%	0.041	29%	0.294	C	S	.	.	H	α-helix	trans	-59.7	-38.7	174	0	0	0	0	0	113.1	P153 M154 L155 Y160 L161	P153-G157 PolarHBondContact O-N 3.41Å; P153-G157 VanDerWaalsContact O-N 3.12Å; M154-G157 CarbonylContact O-C 3.37Å; M154-G157 WeakPolarHBondContact O-CA 3.41Å; M154-G157 PolarHBondContact O-N 3.45Å; L155-G157 VanDerWaalsContact C-N 3.33Å; L155-G157 PolarHBondContact O-N 3.04Å; G157-Y160 PolarHBondContact O-N 3.33Å; G157-L161 WeakPolarHBondContact O-CG 3.18Å; G157-L161 PolarHBondContact O-N 3.42Å
158	I	94.9	Very high	92.8	Very high	0 Å²	0	56.4 Å²	56.4	0%	0	30%	0.299	C	S	.	.	H	α-helix	trans	-62.1	-51.4	175.5	-56.1	177.6	0	0	0	110.2	L109 F110 Y113 M154 L155 I156 Y160 L161 M162 M168 L187	L109-I158 HydrophobicContact CD2-CB 4.09Å; L109-I158 HydrophobicContact CD2-CD1 3.5Å; L109-I158 HydrophobicContact CD2-CG1 3.3Å; L109-I158 HydrophobicContact CD2-CG2 3.82Å; F110-I158 HydrophobicContact CB-CG2 4.19Å; F110-I158 HydrophobicContact CD2-CG2 4.38Å; Y113-I158 HydrophobicContact CD1-CD1 4.47Å; Y113-I158 HydrophobicContact CD2-CD1 4Å; Y113-I158 HydrophobicContact CG-CD1 3.74Å; M154-I158 HydrophobicContact CE-CD1 4.16Å; M154-I158 HydrophobicContact CG-CD1 4.27Å; M154-I158 HydrophobicContact CG-CG1 4.4Å; M154-I158 VanDerWaalsContact O-CG1 3.31Å; M154-I158 WeakPolarHBondContact O-CG1 3.41Å; M154-I158 PolarHBondContact O-N 3.41Å; L155-I158 WeakPolarHBondContact O-CB 3.11Å; L155-I158 PolarHBondContact O-N 3.28Å; I156-I158 VanDerWaalsContact C-N 3.31Å; I156-I158 PolarHBondContact O-N 3.09Å; I158-Y160 VanDerWaalsContact C-N 3.26Å; I158-Y160 PolarHBondContact O-N 3.35Å; I158-L161 WeakPolarHBondContact O-CB 3.49Å; I158-L161 PolarHBondContact O-N 3.47Å; I158-L161 VanDerWaalsContact O-N 3.09Å; I158-M162 PolarHBondContact O-N 3.49Å; I158-M168 HydrophobicContact CG2-CE 3.59Å; I158-M168 HydrophobicContact CG2-SD 3.66Å; I158-M168 WeakPolarHBondContact O-CE 3.3Å; I158-L187 HydrophobicContact CG1-CD2 4.28Å
159	F	94.8	Very high	92.8	Very high	104 Å²	104	56.8 Å²	56.8	46%	0.456	30%	0.302	S	S	.	.	H	α-helix	trans	-62.5	-34.4	179.5	-68.7	-46.5	0	0	0	112.9	F110 L155 I156 M162 N163	F110-F159 HydrophobicContact CD2-CE1 4.25Å; F110-F159 AromaticContact CE2-CE1 3.93Å; F110-F159 HydrophobicContact CE2-CE1 3.93Å; F110-F159 AromaticContact CE2-CZ 3.95Å; F110-F159 HydrophobicContact CE2-CZ 3.95Å; L155-F159 HydrophobicContact CD1-CD2 4.48Å; L155-F159 HydrophobicContact CD1-CE2 3.8Å; L155-F159 HydrophobicContact CD1-CZ 3.95Å; L155-F159 HydrophobicContact CD2-CE2 3.98Å; L155-F159 HydrophobicContact CG-CD2 4.13Å; L155-F159 HydrophobicContact CG-CE2 3.65Å; L155-F159 HydrophobicContact CG-CZ 4.31Å; L155-F159 WeakPolarHBondContact O-CD2 3.27Å; L155-F159 PolarHBondContact O-N 3.21Å; I156-F159 PolarHBondContact O-N 3.31Å; F159-M162 WeakPolarHBondContact O-CB 3.46Å; F159-M162 PolarHBondContact O-N 3.06Å; F159-N163 PolarHBondContact O-N 3.43Å
160	Y	93.9	Very high	92.6	Very high	86 Å²	86	51.3 Å²	51.3	34%	0.337	27%	0.273	S	S	.	.	H	α-helix	trans	-62.7	-44.4	172.5	-178.7	-88.2	0	0	0	112.4	I156 G157 I158 M162 N163 K164 Y180 L183	I156-Y160 PolarHBondContact O-N 3.21Å; G157-Y160 PolarHBondContact O-N 3.33Å; I158-Y160 VanDerWaalsContact C-N 3.26Å; I158-Y160 PolarHBondContact O-N 3.35Å; Y160-M162 VanDerWaalsContact C-N 3.27Å; Y160-M162 PolarHBondContact O-N 3.44Å; Y160-N163 PolarHBondContact O-N 3.4Å; Y160-K164 HydrophobicContact CD1-CG 4.22Å; Y160-K164 HydrophobicContact CE1-CG 3.77Å; Y160-K164 VanDerWaalsContact CZ-CE 3.48Å; Y160-K164 PolarHBondContact O-N 2.8Å; Y160-K164 WeakPolarHBondContact OH-CE 3.26Å; Y160-Y180 HydrophobicContact CE1-CD2 4.21Å; Y160-Y180 HydrophobicContact CE1-CE2 4.33Å; Y160-L183 HydrophobicContact CD1-CD1 3.42Å; Y160-L183 VanDerWaalsContact CD1-CD1 3.42Å; Y160-L183 HydrophobicContact CE1-CD1 3.73Å
161	L	92.6	Very high	92.3	Very high	0 Å²	0	53.5 Å²	53.5	0%	0	28%	0.278	C	S	.	.	H	α-helix	trans	-59.5	-39	174.4	-74	174.2	0	0	0	111.6	G157 I158 N163 K164 I165 M168 M173 F178 L183 L187 F237	G157-L161 WeakPolarHBondContact O-CG 3.18Å; G157-L161 PolarHBondContact O-N 3.42Å; I158-L161 WeakPolarHBondContact O-CB 3.49Å; I158-L161 PolarHBondContact O-N 3.47Å; I158-L161 VanDerWaalsContact O-N 3.09Å; L161-N163 VanDerWaalsContact C-N 3.3Å; L161-N163 PolarHBondContact O-N 3.39Å; L161-K164 PolarHBondContact O-N 3.16Å; L161-I165 HydrophobicContact CB-CD1 4.25Å; L161-I165 HydrophobicContact CD2-CD1 3.96Å; L161-I165 PolarHBondContact O-N 3.48Å; L161-I165 VanDerWaalsContact O-N 3.07Å; L161-M168 HydrophobicContact CB-CE 4.17Å; L161-M173 HydrophobicContact CB-CE 4.22Å; L161-M173 HydrophobicContact CD1-CE 3.8Å; L161-M173 HydrophobicContact CD2-CE 3.99Å; L161-M173 HydrophobicContact CG-CE 4.23Å; L161-F178 HydrophobicContact CD2-CD1 4.21Å; L161-F178 HydrophobicContact CD2-CD2 4.14Å; L161-F178 HydrophobicContact CD2-CE1 4.09Å; L161-F178 HydrophobicContact CD2-CE2 4.01Å; L161-F178 HydrophobicContact CD2-CG 4.28Å; L161-F178 HydrophobicContact CD2-CZ 4.06Å; L161-L183 HydrophobicContact CD2-CD1 3.64Å; L161-L183 HydrophobicContact CD2-CD2 4.24Å; L161-L183 HydrophobicContact CD2-CG 4.48Å; L161-L183 HydrophobicContact CG-CD1 3.99Å; L161-L187 HydrophobicContact CD1-CD1 3.66Å; L161-L187 HydrophobicContact CD1-CD2 4.43Å; L161-F237 HydrophobicContact CD1-CE2 4Å; L161-F237 HydrophobicContact CD1-CZ 4.26Å
162	M	92.9	Very high	92.1	Very high	78 Å²	78	57.5 Å²	57.5	38%	0.384	30%	0.299	S	S	.	.	H	α-helix	trans	-57.2	-47.7	177.8	-170.9	44	-169.8	0	0	111.2	I158 F159 Y160 K164 G166 M168	I158-M162 PolarHBondContact O-N 3.49Å; F159-M162 WeakPolarHBondContact O-CB 3.46Å; F159-M162 PolarHBondContact O-N 3.06Å; Y160-M162 VanDerWaalsContact C-N 3.27Å; Y160-M162 PolarHBondContact O-N 3.44Å; M162-K164 PolarHBondContact O-N 3.05Å; M162-G166 WeakPolarHBondContact CE-O 3.34Å; M162-G166 WeakPolarHBondContact O-CA 3.16Å; M162-G166 PolarHBondContact O-N 3.49Å; M162-M168 HydrophobicContact CB-CE 3.3Å; M162-M168 HydrophobicContact CG-CE 4.14Å; M162-M168 HydrophobicContact SD-CE 4.2Å; M162-M168 HydrophobicContact SD-CG 4.02Å
163	N	92.4	Very high	91.9	Very high	140 Å²	140	53 Å²	53	75%	0.749	28%	0.275	S	S	*	.	H	α-helix	trans	-67.1	-26.9	-176.9	-66.8	-12.4	0	0	0	112.5	F159 Y160 L161	F159-N163 PolarHBondContact O-N 3.43Å; Y160-N163 PolarHBondContact O-N 3.4Å; L161-N163 VanDerWaalsContact C-N 3.3Å; L161-N163 PolarHBondContact O-N 3.39Å
164	K	89.8	Confident	91.4	Very high	118 Å²	118	53.9 Å²	53.9	51%	0.513	28%	0.277	S	S	.	.	H	α-helix	trans	-84.7	-37.6	-178.9	-70.8	-63.8	-174.6	-178.7	0	113.8	Y160 L161 M162	Y160-K164 HydrophobicContact CD1-CG 4.22Å; Y160-K164 HydrophobicContact CE1-CG 3.77Å; Y160-K164 VanDerWaalsContact CZ-CE 3.48Å; Y160-K164 PolarHBondContact O-N 2.8Å; Y160-K164 WeakPolarHBondContact OH-CE 3.26Å; L161-K164 PolarHBondContact O-N 3.16Å; M162-K164 PolarHBondContact O-N 3.05Å
165	I	89.6	Confident	90.9	Very high	31 Å²	31	60.2 Å²	60.2	16%	0.159	31%	0.311	C	S	.	.	H	α-helix	trans	-108.7	-26.8	-168.1	-57.4	153	0	0	0	111.3	L161 S167 M173 F176 F178	L161-I165 HydrophobicContact CB-CD1 4.25Å; L161-I165 HydrophobicContact CD2-CD1 3.96Å; L161-I165 PolarHBondContact O-N 3.48Å; L161-I165 VanDerWaalsContact O-N 3.07Å; I165-S167 PolarHBondContact O-N 3.26Å; I165-M173 HydrophobicContact CB-SD 4.32Å; I165-M173 HydrophobicContact CD1-CE 3.17Å; I165-M173 HydrophobicContact CD1-SD 3.19Å; I165-M173 WeakPolarHBondContact CD1-SD 3.24Å; I165-M173 HydrophobicContact CG1-SD 4.3Å; I165-M173 HydrophobicContact CG2-SD 4.01Å; I165-F176 HydrophobicContact CG1-CD2 4.49Å; I165-F176 HydrophobicContact CG2-CD2 3.82Å; I165-F176 HydrophobicContact CG2-CE2 3.44Å; I165-F176 VanDerWaalsContact CG2-CE2 3.44Å; I165-F176 HydrophobicContact CG2-CZ 3.98Å; I165-F178 HydrophobicContact CD1-CE1 3.76Å; I165-F178 HydrophobicContact CD1-CE2 3.8Å; I165-F178 HydrophobicContact CD1-CZ 3.06Å; I165-F178 HydrophobicContact CG1-CE1 3.95Å; I165-F178 HydrophobicContact CG1-CZ 3.54Å
166	G	88.5	Confident	90.5	Very high	52 Å²	52	62.8 Å²	62.8	54%	0.536	32%	0.32	S	S	.	.	S	Bend	trans	74.9	-0.7	-174.4	0	0	0	0	0	114.5	M162	M162-G166 WeakPolarHBondContact CE-O 3.34Å; M162-G166 WeakPolarHBondContact O-CA 3.16Å; M162-G166 PolarHBondContact O-N 3.49Å
167	S	89.8	Confident	90	Very high	25 Å²	25	61.9 Å²	61.9	18%	0.175	32%	0.315	C	S	.	.			trans	-138.8	152.4	176.7	79.7	0	0	0	0	112	I165 M173	I165-S167 PolarHBondContact O-N 3.26Å; S167-M173 VanDerWaalsContact O-SD 3.38Å
168	M	90.6	Very high	89.6	Confident	25 Å²	25	62.4 Å²	62.4	12%	0.123	32%	0.316	C	S	.	.			trans	-112.4	0.9	-178.4	-82	-67.3	159	0	0	114.1	S108 L109 F110 I158 L161 M162	S108-M168 CarbonylContact C-O 3.59Å; S108-M168 VanDerWaalsContact CA-O 3.29Å; S108-M168 WeakPolarHBondContact CA-O 3.45Å; L109-M168 HydrophobicContact CB-SD 4.19Å; L109-M168 PolarHBondContact N-O 2.96Å; F110-M168 HydrophobicContact CB-CG 4.48Å; I158-M168 HydrophobicContact CG2-CE 3.59Å; I158-M168 HydrophobicContact CG2-SD 3.66Å; I158-M168 WeakPolarHBondContact O-CE 3.3Å; L161-M168 HydrophobicContact CB-CE 4.17Å; M162-M168 HydrophobicContact CB-CE 3.3Å; M162-M168 HydrophobicContact CG-CE 4.14Å; M162-M168 HydrophobicContact SD-CE 4.2Å; M162-M168 HydrophobicContact SD-CG 4.02Å
169	N	92.6	Very high	89.2	Confident	73 Å²	73	66.9 Å²	66.9	39%	0.39	34%	0.34	S	S	.	.	B	Isolated β-bridge	trans	-78.5	126.4	-173.6	-69.1	-16.5	0	0	0	110.4	M107 Y171 L172 M173	M107-N169 CarbonylContact O-C 3.59Å; M107-N169 WeakPolarHBondContact O-CA 3.39Å; N169-Y171 PolarHBondContact O-N 2.67Å; N169-L172 HydrophobicContact CB-CD1 4.4Å; N169-L172 PolarHBondContact O-N 2.93Å; N169-M173 VanDerWaalsContact O-CG 3.23Å; N169-M173 WeakPolarHBondContact O-CG 3.34Å; N169-M173 PolarHBondContact O-N 2.81Å
170	F	89.6	Confident	89	Confident	2 Å²	2	66.9 Å²	66.9	1%	0.009	34%	0.338	C	S	.	.	H	α-helix	trans	-49	-41.1	-178.8	-73.2	-61.3	0	0	0	112.7	W45 S106 M107 L109 F112 L172 M173 N174 R233	W45-F170 HydrophobicContact CH2-CD2 4.15Å; W45-F170 HydrophobicContact CZ2-CB 4.28Å; W45-F170 HydrophobicContact CZ2-CD2 4.1Å; S106-F170 WeakPolarHBondContact O-CE2 3.12Å; M107-F170 VanDerWaalsContact C-CD2 3.49Å; M107-F170 WeakPolarHBondContact O-CD2 3.34Å; M107-F170 PolarHBondContact O-N 3.21Å; L109-F170 HydrophobicContact CB-CE1 3.96Å; L109-F170 HydrophobicContact CB-CZ 4.11Å; L109-F170 HydrophobicContact CD1-CD1 4.46Å; L109-F170 HydrophobicContact CD1-CE1 3.8Å; L109-F170 HydrophobicContact CG-CE1 3.92Å; L109-F170 HydrophobicContact CG-CZ 4.22Å; F112-F170 HydrophobicContact CB-CE2 4.26Å; F112-F170 HydrophobicContact CB-CZ 4.09Å; F112-F170 HydrophobicContact CD1-CZ 4.37Å; F112-F170 HydrophobicContact CG-CZ 4.21Å; F170-L172 PolarHBondContact O-N 3.44Å; F170-M173 PolarHBondContact O-N 3.22Å; F170-N174 PolarHBondContact O-N 3.16Å; F170-N174 PolarHBondContact O-OD1 2.92Å; F170-R233 HydrophobicContact CD1-CB 3.99Å; F170-R233 HydrophobicContact CE1-CB 3.6Å; F170-R233 HydrophobicContact CE1-CG 4.33Å; F170-R233 HydrophobicContact CZ-CB 3.97Å; F170-R233 HydrophobicContact CZ-CG 4.31Å
171	Y	86.1	Confident	88.9	Confident	84 Å²	84	66.3 Å²	66.3	33%	0.329	34%	0.34	S	S	.	.	H	α-helix	trans	-57.1	-46.7	176.9	-80.6	-69.1	0	0	0	115.2	W45 M107 N169	W45-Y171 WeakPolarHBondContact CA-OH 3.49Å; W45-Y171 HydrophobicContact CB-CE2 3.69Å; W45-Y171 WeakPolarHBondContact CB-OH 3.44Å; W45-Y171 AromaticContact CD1-CE1 3.3Å; W45-Y171 AromaticContact CD1-CE2 3.18Å; W45-Y171 AromaticContact CD1-CZ 2.8Å; W45-Y171 AromaticContact CD2-CE2 3.9Å; W45-Y171 HydrophobicContact CD2-CE2 3.9Å; W45-Y171 AromaticContact CE2-CE2 3.96Å; W45-Y171 HydrophobicContact CG-CD2 4.36Å; W45-Y171 HydrophobicContact CG-CE1 4.15Å; W45-Y171 AromaticContact CG-CE2 3.27Å; W45-Y171 HydrophobicContact CG-CE2 3.27Å; W45-Y171 AromaticContact CG-CZ 3.22Å; W45-Y171 PolarHBondContact N-OH 3.32Å; W45-Y171 AromaticContact NE1-CD2 3.95Å; W45-Y171 AromaticContact NE1-CE1 3.72Å; W45-Y171 AromaticContact NE1-CE2 3.49Å; W45-Y171 AromaticContact NE1-CZ 3.47Å; M107-Y171 HydrophobicContact CE-CD2 4.48Å; M107-Y171 HydrophobicContact CE-CE2 3.72Å; M107-Y171 HydrophobicContact SD-CD2 3.78Å; M107-Y171 HydrophobicContact SD-CE2 3.54Å; M107-Y171 VanDerWaalsContact SD-CE2 3.54Å; N169-Y171 PolarHBondContact O-N 2.67Å
172	L	87.8	Confident	88.9	Confident	85 Å²	85	72.7 Å²	72.7	45%	0.445	37%	0.374	S	S	.	.	H	α-helix	trans	-75.3	-35.6	-179.1	-65.8	174.2	0	0	0	110.2	N169 F170 N174 N175 F176	N169-L172 HydrophobicContact CB-CD1 4.4Å; N169-L172 PolarHBondContact O-N 2.93Å; F170-L172 PolarHBondContact O-N 3.44Å; L172-N174 VanDerWaalsContact C-N 3.3Å; L172-N174 PolarHBondContact O-N 3.09Å; L172-N175 PolarHBondContact O-N 3.12Å; L172-F176 VanDerWaalsContact O-CD2 3.31Å; L172-F176 WeakPolarHBondContact O-CD2 3.35Å; L172-F176 WeakPolarHBondContact O-CE2 3.22Å
173	M	88.3	Confident	88.9	Confident	0 Å²	0	69.3 Å²	69.3	0%	0	36%	0.357	C	S	.	.	H	α-helix	trans	-61	-37	178.2	-65.4	-67.2	-64.5	0	0	112.6	L161 I165 S167 N169 F170 N175 F176 F178 F237	L161-M173 HydrophobicContact CB-CE 4.22Å; L161-M173 HydrophobicContact CD1-CE 3.8Å; L161-M173 HydrophobicContact CD2-CE 3.99Å; L161-M173 HydrophobicContact CG-CE 4.23Å; I165-M173 HydrophobicContact CB-SD 4.32Å; I165-M173 HydrophobicContact CD1-CE 3.17Å; I165-M173 HydrophobicContact CD1-SD 3.19Å; I165-M173 WeakPolarHBondContact CD1-SD 3.24Å; I165-M173 HydrophobicContact CG1-SD 4.3Å; I165-M173 HydrophobicContact CG2-SD 4.01Å; S167-M173 VanDerWaalsContact O-SD 3.38Å; N169-M173 VanDerWaalsContact O-CG 3.23Å; N169-M173 WeakPolarHBondContact O-CG 3.34Å; N169-M173 PolarHBondContact O-N 2.81Å; F170-M173 PolarHBondContact O-N 3.22Å; M173-N175 PolarHBondContact O-N 3.4Å; M173-N175 VanDerWaalsContact O-N 3.09Å; M173-F176 PolarHBondContact O-N 3.12Å; M173-F178 HydrophobicContact CE-CE2 4.09Å; M173-F178 HydrophobicContact CE-CZ 4.46Å; M173-F237 HydrophobicContact CB-CD1 4.1Å; M173-F237 HydrophobicContact CB-CG 4.44Å; M173-F237 HydrophobicContact CE-CD2 4.43Å; M173-F237 HydrophobicContact CE-CE2 4.47Å; M173-F237 WeakPolarHBondContact O-CB 3.19Å
174	N	85.9	Confident	88.9	Confident	67 Å²	67	62.7 Å²	62.7	36%	0.358	32%	0.322	S	S	.	.	T	Hydrogen-bonded Turn	trans	-59.4	-21.7	-179.2	-73.9	-6.8	0	0	0	114	F170 L172 F176 S236	F170-N174 PolarHBondContact O-N 3.16Å; F170-N174 PolarHBondContact O-OD1 2.92Å; L172-N174 VanDerWaalsContact C-N 3.3Å; L172-N174 PolarHBondContact O-N 3.09Å; N174-F176 VanDerWaalsContact C-N 3.29Å; N174-S236 WeakPolarHBondContact OD1-CB 2.85Å; N174-S236 PolarHBondContact OD1-OG 2.79Å
175	N	84.6	Confident	89.1	Confident	133 Å²	133	60.8 Å²	60.8	71%	0.711	31%	0.314	S	S	*	.	T	Hydrogen-bonded Turn	trans	-79.9	-12.3	178.3	-65.3	-13.8	0	0	0	112.9	L172 M173	L172-N175 PolarHBondContact O-N 3.12Å; M173-N175 PolarHBondContact O-N 3.4Å; M173-N175 VanDerWaalsContact O-N 3.09Å
176	F	85.6	Confident	89.3	Confident	93 Å²	93	60.4 Å²	60.4	41%	0.408	31%	0.314	S	S	.	.			trans	-101.9	139.9	-178.8	-62.7	-80.2	0	0	0	111.3	I165 L172 M173 N174 F178	I165-F176 HydrophobicContact CG1-CD2 4.49Å; I165-F176 HydrophobicContact CG2-CD2 3.82Å; I165-F176 HydrophobicContact CG2-CE2 3.44Å; I165-F176 VanDerWaalsContact CG2-CE2 3.44Å; I165-F176 HydrophobicContact CG2-CZ 3.98Å; L172-F176 VanDerWaalsContact O-CD2 3.31Å; L172-F176 WeakPolarHBondContact O-CD2 3.35Å; L172-F176 WeakPolarHBondContact O-CE2 3.22Å; M173-F176 PolarHBondContact O-N 3.12Å; N174-F176 VanDerWaalsContact C-N 3.29Å; F176-F178 HydrophobicContact CB-CE1 4.37Å; F176-F178 HydrophobicContact CB-CE2 3.62Å; F176-F178 HydrophobicContact CB-CZ 3.44Å; F176-F178 VanDerWaalsContact CB-CZ 3.44Å; F176-F178 HydrophobicContact CG-CZ 4.15Å
177	M	86	Confident	89.6	Confident	99 Å²	99	57.9 Å²	57.9	49%	0.488	29%	0.288	S	S	.	.			trans	-110.9	109.1	174.8	-71.7	-70.4	-160.7	0	0	109.6	Q239 L240	M177-Q239 HydrophobicContact CE-CB 4.33Å; M177-Q239 HydrophobicContact CE-CG 4.49Å; M177-Q239 HydrophobicContact SD-CB 4.13Å; M177-Q239 HydrophobicContact SD-CG 4.47Å; M177-L240 HydrophobicContact CB-CD1 3.78Å; M177-L240 HydrophobicContact CB-CG 4.45Å; M177-L240 HydrophobicContact CG-CD1 4.38Å; M177-L240 HydrophobicContact SD-CD1 4.48Å; M177-L240 HydrophobicContact SD-CG 4.18Å
178	F	85.4	Confident	89.8	Confident	15 Å²	15	56.8 Å²	56.8	7%	0.066	28%	0.28	C	S	.	.			trans	-89.7	136.3	-179.9	-62.4	-74.5	0	0	0	112.2	L161 I165 M173 F176 Y180 F237 L238 M241	L161-F178 HydrophobicContact CD2-CD1 4.21Å; L161-F178 HydrophobicContact CD2-CD2 4.14Å; L161-F178 HydrophobicContact CD2-CE1 4.09Å; L161-F178 HydrophobicContact CD2-CE2 4.01Å; L161-F178 HydrophobicContact CD2-CG 4.28Å; L161-F178 HydrophobicContact CD2-CZ 4.06Å; I165-F178 HydrophobicContact CD1-CE1 3.76Å; I165-F178 HydrophobicContact CD1-CE2 3.8Å; I165-F178 HydrophobicContact CD1-CZ 3.06Å; I165-F178 HydrophobicContact CG1-CE1 3.95Å; I165-F178 HydrophobicContact CG1-CZ 3.54Å; M173-F178 HydrophobicContact CE-CE2 4.09Å; M173-F178 HydrophobicContact CE-CZ 4.46Å; F176-F178 HydrophobicContact CB-CE1 4.37Å; F176-F178 HydrophobicContact CB-CE2 3.62Å; F176-F178 HydrophobicContact CB-CZ 3.44Å; F176-F178 VanDerWaalsContact CB-CZ 3.44Å; F176-F178 HydrophobicContact CG-CZ 4.15Å; F178-Y180 HydrophobicContact CD1-CD2 4.39Å; F178-Y180 HydrophobicContact CD1-CE2 4.39Å; F178-F237 HydrophobicContact CD2-CB 4.48Å; F178-F237 AromaticContact CD2-CD2 3.91Å; F178-F237 HydrophobicContact CD2-CD2 3.91Å; F178-F237 HydrophobicContact CE2-CB 4.42Å; F178-F237 HydrophobicContact CE2-CD2 4.17Å; F178-L238 HydrophobicContact CB-CD2 4.26Å; F178-M241 VanDerWaalsContact O-CG 3.28Å; F178-M241 WeakPolarHBondContact O-CG 3.43Å
179	N	87	Confident	89.9	Confident	94 Å²	94	57.4 Å²	57.4	50%	0.503	29%	0.286	S	S	.	.			trans	-112.9	24.8	-179.2	-80.6	-18.1	0	0	0	114.1	L240 M241	N179-L240 WeakPolarHBondContact OD1-CB 3.3Å; N179-L240 WeakPolarHBondContact OD1-CD1 3.4Å; N179-M241 VanDerWaalsContact CA-SD 3.57Å
180	Y	89.9	Confident	90	Very high	105 Å²	105	54.1 Å²	54.1	41%	0.412	27%	0.269	S	S	.	.			trans	-101.6	117.9	-174.9	-58.3	-70	0	0	0	112.2	Y160 F178 L183 Y184	Y160-Y180 HydrophobicContact CE1-CD2 4.21Å; Y160-Y180 HydrophobicContact CE1-CE2 4.33Å; F178-Y180 HydrophobicContact CD1-CD2 4.39Å; F178-Y180 HydrophobicContact CD1-CE2 4.39Å; Y180-L183 PolarHBondContact O-N 2.8Å; Y180-Y184 PolarHBondContact O-N 3.11Å
181	D	92	Very high	90.2	Very high	73 Å²	73	54 Å²	54	39%	0.39	27%	0.269	S	S	.	.	H	α-helix	trans	-61.5	-48.1	-177.6	-66.2	-58.1	0	0	0	112.7	L183 Y184 F185 M241 Y245	D181-L183 VanDerWaalsContact C-N 3.27Å; D181-L183 PolarHBondContact O-N 2.87Å; D181-Y184 WeakPolarHBondContact O-CB 3.04Å; D181-Y184 PolarHBondContact O-N 3.24Å; D181-Y184 VanDerWaalsContact O-N 3.17Å; D181-F185 VanDerWaalsContact O-CD2 3.24Å; D181-F185 WeakPolarHBondContact O-CD2 3.33Å; D181-F185 PolarHBondContact O-N 3.42Å; D181-M241 HydrophobicContact CB-CE 4Å; D181-M241 WeakPolarHBondContact OD1-CE 3.37Å; D181-Y245 VanDerWaalsContact OD1-CE2 3.27Å; D181-Y245 WeakPolarHBondContact OD1-CE2 3.39Å; D181-Y245 PolarHBondContact OD1-OH 3.43Å
182	L	92.5	Very high	90.6	Very high	135 Å²	135	50.3 Å²	50.3	71%	0.707	26%	0.255	S	S	*	.	H	α-helix	trans	-62.4	-37.6	-178.2	-174	144.2	0	0	0	111.9	Y184 F185 C186	L182-Y184 VanDerWaalsContact C-N 3.33Å; L182-Y184 PolarHBondContact O-N 2.88Å; L182-F185 PolarHBondContact O-N 3.34Å; L182-C186 PolarHBondContact O-N 2.63Å; L182-C186 PolarHBondContact O-SG 2.92Å
183	L	92.5	Very high	90.9	Very high	7 Å²	7	46.6 Å²	46.6	4%	0.037	24%	0.235	C	C	.	.	H	α-helix	trans	-64.7	-39.1	178.1	-173.7	145.1	0	0	0	111.8	Y160 L161 Y180 D181 C186 L187 L238	Y160-L183 HydrophobicContact CD1-CD1 3.42Å; Y160-L183 VanDerWaalsContact CD1-CD1 3.42Å; Y160-L183 HydrophobicContact CE1-CD1 3.73Å; L161-L183 HydrophobicContact CD2-CD1 3.64Å; L161-L183 HydrophobicContact CD2-CD2 4.24Å; L161-L183 HydrophobicContact CD2-CG 4.48Å; L161-L183 HydrophobicContact CG-CD1 3.99Å; Y180-L183 PolarHBondContact O-N 2.8Å; D181-L183 VanDerWaalsContact C-N 3.27Å; D181-L183 PolarHBondContact O-N 2.87Å; L183-C186 PolarHBondContact O-N 3.13Å; L183-L187 HydrophobicContact CD2-CD1 3.42Å; L183-L187 VanDerWaalsContact CD2-CD1 3.42Å; L183-L187 HydrophobicContact CD2-CG 4.35Å; L183-L187 HydrophobicContact CG-CD1 3.99Å; L183-L187 WeakPolarHBondContact O-CG 3.15Å; L183-L187 PolarHBondContact O-N 3.05Å; L183-L238 HydrophobicContact CD2-CD2 3.45Å; L183-L238 VanDerWaalsContact CD2-CD2 3.45Å
184	Y	93.8	Very high	91.1	Very high	0 Å²	0	46.8 Å²	46.8	0%	0	24%	0.236	C	C	.	.	H	α-helix	trans	-58.3	-50.1	175.3	172.6	-92.7	0	0	0	111.4	Y180 D181 L182 L187 L188 L238 M241 N242 Y245 W249	Y180-Y184 PolarHBondContact O-N 3.11Å; D181-Y184 WeakPolarHBondContact O-CB 3.04Å; D181-Y184 PolarHBondContact O-N 3.24Å; D181-Y184 VanDerWaalsContact O-N 3.17Å; L182-Y184 VanDerWaalsContact C-N 3.33Å; L182-Y184 PolarHBondContact O-N 2.88Å; Y184-L187 PolarHBondContact O-N 3.08Å; Y184-L188 HydrophobicContact CD1-CD1 4.07Å; Y184-L188 HydrophobicContact CD2-CD1 3.38Å; Y184-L188 HydrophobicContact CD2-CG 4.44Å; Y184-L188 HydrophobicContact CE1-CD1 3.67Å; Y184-L188 HydrophobicContact CE2-CD1 2.93Å; Y184-L188 HydrophobicContact CE2-CG 4.29Å; Y184-L188 HydrophobicContact CG-CD1 3.94Å; Y184-L188 WeakPolarHBondContact O-CB 3.33Å; Y184-L188 PolarHBondContact O-N 3.49Å; Y184-L188 WeakPolarHBondContact OH-CD1 3.5Å; Y184-L238 HydrophobicContact CD2-CD1 4.35Å; Y184-M241 HydrophobicContact CD2-CB 3.43Å; Y184-M241 VanDerWaalsContact CD2-CB 3.43Å; Y184-M241 HydrophobicContact CE2-CB 4.15Å; Y184-M241 HydrophobicContact CG-CB 3.86Å; Y184-N242 VanDerWaalsContact CE2-CA 3.45Å; Y184-N242 HydrophobicContact CE2-CB 3.94Å; Y184-N242 PolarHBondContact OH-OD1 3.37Å; Y184-Y245 AromaticContact CD1-CD2 3.53Å; Y184-Y245 HydrophobicContact CD1-CD2 3.53Å; Y184-Y245 HydrophobicContact CD1-CE2 4.11Å; Y184-Y245 HydrophobicContact CD1-CG 4.18Å; Y184-Y245 AromaticContact CE1-CD2 3.51Å; Y184-Y245 HydrophobicContact CE1-CD2 3.51Å; Y184-Y245 HydrophobicContact CE1-CE2 4.48Å; Y184-Y245 AromaticContact CE1-CG 3.73Å; Y184-Y245 HydrophobicContact CE1-CG 3.73Å; Y184-Y245 HydrophobicContact CG-CD2 4.12Å; Y184-W249 AromaticContact CE1-NE1 3.73Å; Y184-W249 AromaticContact CZ-NE1 3.9Å; Y184-W249 VanDerWaalsContact OH-CD1 3.32Å; Y184-W249 PolarHBondContact OH-NE1 2.92Å
185	F	93.6	Very high	91.3	Very high	78 Å²	78	43.7 Å²	43.7	34%	0.342	22%	0.22	S	C	.	.	H	α-helix	trans	-64.9	-43.6	178.4	-71.3	-69.9	0	0	0	112.3	D181 L182 L187 C189 Y245 W249	D181-F185 VanDerWaalsContact O-CD2 3.24Å; D181-F185 WeakPolarHBondContact O-CD2 3.33Å; D181-F185 PolarHBondContact O-N 3.42Å; L182-F185 PolarHBondContact O-N 3.34Å; F185-L187 VanDerWaalsContact C-N 3.33Å; F185-L187 PolarHBondContact O-N 3.21Å; F185-C189 VanDerWaalsContact O-CB 3.27Å; F185-C189 WeakPolarHBondContact O-CB 3.37Å; F185-C189 PolarHBondContact O-N 3.2Å; F185-C189 VanDerWaalsContact O-N 3.13Å; F185-C189 PolarHBondContact O-SG 3.5Å; F185-Y245 HydrophobicContact CE2-CE1 4.12Å; F185-Y245 HydrophobicContact CE2-CE2 4.18Å; F185-Y245 AromaticContact CE2-CZ 3.88Å; F185-Y245 AromaticContact CZ-CD1 3.99Å; F185-Y245 HydrophobicContact CZ-CD1 3.99Å; F185-Y245 AromaticContact CZ-CE1 3.81Å; F185-Y245 HydrophobicContact CZ-CE1 3.81Å; F185-Y245 HydrophobicContact CZ-CE2 4.38Å; F185-Y245 HydrophobicContact CZ-CG 4.36Å; F185-W249 HydrophobicContact CD1-CZ2 4.17Å; F185-W249 AromaticContact CE1-CZ2 3.95Å; F185-W249 HydrophobicContact CE1-CZ2 3.95Å
186	C	94.1	Very high	91.1	Very high	23 Å²	23	37.5 Å²	37.5	16%	0.155	19%	0.187	C	C	.	.	H	α-helix	trans	-58.6	-42.8	178.6	-72.5	0	0	0	0	112.6	M154 L182 L183	M154-C186 VanDerWaalsContact CA-O 3.25Å; M154-C186 WeakPolarHBondContact CA-O 3.37Å; M154-C186 WeakPolarHBondContact CB-O 3.38Å; M154-C186 PolarHBondContact N-O 3.04Å; L182-C186 PolarHBondContact O-N 2.63Å; L182-C186 PolarHBondContact O-SG 2.92Å; L183-C186 PolarHBondContact O-N 3.13Å
187	L	93.7	Very high	91.4	Very high	0 Å²	0	33.5 Å²	33.5	0%	0	17%	0.17	C	C	.	.	H	α-helix	trans	-80.6	-35.6	-175.7	-66.6	175.3	0	0	0	113.4	M154 I158 L161 L183 Y184 F185 F191 V234 F237 L238	M154-L187 HydrophobicContact CG-CD2 4.08Å; I158-L187 HydrophobicContact CG1-CD2 4.28Å; L161-L187 HydrophobicContact CD1-CD1 3.66Å; L161-L187 HydrophobicContact CD1-CD2 4.43Å; L183-L187 HydrophobicContact CD2-CD1 3.42Å; L183-L187 VanDerWaalsContact CD2-CD1 3.42Å; L183-L187 HydrophobicContact CD2-CG 4.35Å; L183-L187 HydrophobicContact CG-CD1 3.99Å; L183-L187 WeakPolarHBondContact O-CG 3.15Å; L183-L187 PolarHBondContact O-N 3.05Å; Y184-L187 PolarHBondContact O-N 3.08Å; F185-L187 VanDerWaalsContact C-N 3.33Å; F185-L187 PolarHBondContact O-N 3.21Å; L187-F191 WeakPolarHBondContact O-CD2 3.46Å; L187-F191 VanDerWaalsContact O-CE2 3.31Å; L187-F191 WeakPolarHBondContact O-CE2 3.49Å; L187-V234 HydrophobicContact CB-CG1 3.91Å; L187-V234 HydrophobicContact CD1-CG1 4.41Å; L187-F237 HydrophobicContact CD1-CE2 3.84Å; L187-F237 HydrophobicContact CD1-CZ 4.23Å; L187-L238 HydrophobicContact CB-CD1 4.11Å; L187-L238 HydrophobicContact CD1-CD1 4.03Å; L187-L238 HydrophobicContact CD1-CD2 4.4Å
188	L	94.3	Very high	91.5	Very high	2 Å²	2	31.2 Å²	31.2	1%	0.01	16%	0.157	C	C	.	.	H	α-helix	trans	-84.8	-35.3	-175.7	-70.3	172.3	0	0	0	114	Y184 A190 F191 L192 M231 V234 I235 L238	Y184-L188 HydrophobicContact CD1-CD1 4.07Å; Y184-L188 HydrophobicContact CD2-CD1 3.38Å; Y184-L188 HydrophobicContact CD2-CG 4.44Å; Y184-L188 HydrophobicContact CE1-CD1 3.67Å; Y184-L188 HydrophobicContact CE2-CD1 2.93Å; Y184-L188 HydrophobicContact CE2-CG 4.29Å; Y184-L188 HydrophobicContact CG-CD1 3.94Å; Y184-L188 WeakPolarHBondContact O-CB 3.33Å; Y184-L188 PolarHBondContact O-N 3.49Å; Y184-L188 WeakPolarHBondContact OH-CD1 3.5Å; L188-A190 PolarHBondContact O-N 3Å; L188-A190 VanDerWaalsContact O-N 3.13Å; L188-F191 PolarHBondContact O-N 3.08Å; L188-L192 WeakPolarHBondContact O-CG 3.45Å; L188-L192 PolarHBondContact O-N 3.24Å; L188-L192 VanDerWaalsContact O-N 3.07Å; L188-M231 HydrophobicContact CB-SD 4.45Å; L188-M231 HydrophobicContact CD2-CE 3.85Å; L188-M231 HydrophobicContact CD2-SD 3.31Å; L188-M231 WeakPolarHBondContact CD2-SD 3.24Å; L188-M231 HydrophobicContact CG-SD 4.43Å; L188-V234 HydrophobicContact CD2-CG1 4.27Å; L188-I235 HydrophobicContact CD2-CG1 4.15Å; L188-L238 HydrophobicContact CG-CD1 4.34Å
189	C	93.5	Very high	91.8	Very high	37 Å²	37	36.2 Å²	36.2	25%	0.25	18%	0.184	C	C	.	.	H	α-helix	trans	-55.2	-38.1	-174	-75.6	0	0	0	0	112.4	V150 F185 F191 L192 V193	V150-C189 HydrophobicContact CG1-CB 3.48Å; V150-C189 VanDerWaalsContact CG1-CB 3.48Å; V150-C189 WeakPolarHBondContact CG1-O 3.46Å; F185-C189 VanDerWaalsContact O-CB 3.27Å; F185-C189 WeakPolarHBondContact O-CB 3.37Å; F185-C189 PolarHBondContact O-N 3.2Å; F185-C189 VanDerWaalsContact O-N 3.13Å; F185-C189 PolarHBondContact O-SG 3.5Å; C189-F191 VanDerWaalsContact C-N 3.29Å; C189-F191 PolarHBondContact O-N 3.44Å; C189-L192 PolarHBondContact O-N 3.34Å; C189-V193 WeakPolarHBondContact O-CG2 3.49Å; C189-V193 PolarHBondContact O-N 3.37Å
190	A	93.8	Very high	92.1	Very high	4 Å²	4	33.9 Å²	33.9	3%	0.033	17%	0.173	C	C	.	.	H	α-helix	trans	-60.1	-40	179.5	0	0	0	0	0	112.3	M154 L188 K194	M154-A190 HydrophobicContact CB-CB 3.98Å; M154-A190 HydrophobicContact CG-CB 4.43Å; M154-A190 HydrophobicContact SD-CB 3.79Å; L188-A190 PolarHBondContact O-N 3Å; L188-A190 VanDerWaalsContact O-N 3.13Å; A190-K194 PolarHBondContact O-N 3.32Å
191	F	94.4	Very high	92.3	Very high	0 Å²	0	29.7 Å²	29.7	0%	0	16%	0.157	C	C	.	.	H	α-helix	trans	-77.2	-31.6	177.8	-54.7	-53.6	0	0	0	113	F112 F116 M154 L187 L188 C189 V193 K194 M195 G230 M231 V234	F112-F191 AromaticContact CE1-CE1 3.62Å; F112-F191 HydrophobicContact CE1-CE1 3.62Å; F112-F191 AromaticContact CE1-CZ 3.72Å; F112-F191 HydrophobicContact CE1-CZ 3.72Å; F112-F191 HydrophobicContact CZ-CE1 4.04Å; F112-F191 HydrophobicContact CZ-CZ 4.48Å; F116-F191 HydrophobicContact CE2-CD1 4.27Å; F116-F191 HydrophobicContact CE2-CE1 4.3Å; F116-F191 HydrophobicContact CZ-CD1 4.05Å; F116-F191 HydrophobicContact CZ-CE1 4.17Å; M154-F191 HydrophobicContact CE-CE1 4.07Å; M154-F191 HydrophobicContact CE-CE2 4.18Å; M154-F191 HydrophobicContact CE-CZ 3.42Å; M154-F191 VanDerWaalsContact CE-CZ 3.42Å; M154-F191 HydrophobicContact SD-CE1 4.26Å; M154-F191 HydrophobicContact SD-CE2 4.46Å; M154-F191 HydrophobicContact SD-CZ 3.94Å; L187-F191 WeakPolarHBondContact O-CD2 3.46Å; L187-F191 VanDerWaalsContact O-CE2 3.31Å; L187-F191 WeakPolarHBondContact O-CE2 3.49Å; L188-F191 PolarHBondContact O-N 3.08Å; C189-F191 VanDerWaalsContact C-N 3.29Å; C189-F191 PolarHBondContact O-N 3.44Å; F191-V193 PolarHBondContact O-N 3.37Å; F191-K194 PolarHBondContact O-N 3.03Å; F191-M195 WeakPolarHBondContact O-CB 3.31Å; F191-M195 PolarHBondContact O-N 3.49Å; F191-G230 VanDerWaalsContact CE1-CA 3.49Å; F191-M231 HydrophobicContact CB-CG 3.51Å; F191-M231 HydrophobicContact CB-SD 3.47Å; F191-M231 WeakPolarHBondContact CB-SD 3.31Å; F191-M231 HydrophobicContact CD2-CG 4.25Å; F191-M231 HydrophobicContact CD2-SD 3.83Å; F191-M231 HydrophobicContact CG-CG 4.11Å; F191-M231 HydrophobicContact CG-SD 4.08Å; F191-V234 HydrophobicContact CE2-CB 3.97Å; F191-V234 HydrophobicContact CE2-CG1 4.4Å; F191-V234 HydrophobicContact CE2-CG2 3.59Å; F191-V234 HydrophobicContact CZ-CG2 3.99Å
192	L	94.6	Very high	92.4	Very high	6 Å²	6	30.4 Å²	30.4	3%	0.031	16%	0.16	C	C	.	.	H	α-helix	trans	-64.9	-23.7	174.2	-64.3	178.4	0	0	0	113.1	L188 C189 M195 M197 M231 W249 L286	L188-L192 WeakPolarHBondContact O-CG 3.45Å; L188-L192 PolarHBondContact O-N 3.24Å; L188-L192 VanDerWaalsContact O-N 3.07Å; C189-L192 PolarHBondContact O-N 3.34Å; L192-M195 CarbonylContact C-O 3.6Å; L192-M195 CarbonylContact O-C 3.53Å; L192-M197 HydrophobicContact CD1-CE 4.06Å; L192-M197 HydrophobicContact CD2-CE 3.64Å; L192-M197 HydrophobicContact CG-CE 4.33Å; L192-M197 PolarHBondContact O-N 3.08Å; L192-M197 VanDerWaalsContact O-N 3.17Å; L192-M231 HydrophobicContact CD2-CE 3.53Å; L192-M231 HydrophobicContact CG-CE 4.25Å; L192-W249 HydrophobicContact CD1-CD2 3.92Å; L192-W249 HydrophobicContact CD1-CE3 3.95Å; L192-W249 HydrophobicContact CD1-CH2 3.59Å; L192-W249 HydrophobicContact CD1-CZ2 3.61Å; L192-W249 HydrophobicContact CD1-CZ3 3.77Å; L192-L286 HydrophobicContact CD2-CD1 3.72Å; L192-L286 HydrophobicContact CD2-CG 4.43Å
193	V	94.2	Very high	92.5	Very high	7 Å²	7	24.1 Å²	24.1	4%	0.042	13%	0.127	C	C	.	.	H	α-helix	trans	-78.5	-41	171.7	179.5	0	0	0	0	111.5	V150 C189 F191 V200 W203	V150-V193 HydrophobicContact CB-CG2 3.93Å; V150-V193 HydrophobicContact CG1-CG2 3.94Å; V150-V193 HydrophobicContact CG2-CG2 3.76Å; C189-V193 WeakPolarHBondContact O-CG2 3.49Å; C189-V193 PolarHBondContact O-N 3.37Å; F191-V193 PolarHBondContact O-N 3.37Å; V193-V200 HydrophobicContact CB-CG1 4.36Å; V193-V200 HydrophobicContact CG1-CG1 4.01Å; V193-V200 HydrophobicContact CG2-CG1 3.83Å; V193-W203 WeakPolarHBondContact O-CZ2 3.39Å; V193-W203 PolarHBondContact O-NE1 2.94Å
194	K	92.2	Very high	92.5	Very high	4 Å²	4	23.8 Å²	23.8	2%	0.017	13%	0.125	C	C	.	.	H	α-helix	trans	-72.6	-40.2	178.8	-67.7	-73.4	-173.6	144.5	0	113.2	F116 L120 T147 A190 F191 P196 L224	F116-K194 HydrophobicContact CE1-CG 4.38Å; F116-K194 HydrophobicContact CE2-CD 4.35Å; F116-K194 HydrophobicContact CE2-CG 3.89Å; F116-K194 HydrophobicContact CZ-CB 4.45Å; F116-K194 HydrophobicContact CZ-CD 4.04Å; F116-K194 HydrophobicContact CZ-CG 3.43Å; F116-K194 VanDerWaalsContact CZ-CG 3.43Å; L120-K194 VanDerWaalsContact CG-NZ 3.29Å; T147-K194 HydrophobicContact CG2-CD 3.81Å; T147-K194 VanDerWaalsContact CG2-CE 3.49Å; A190-K194 PolarHBondContact O-N 3.32Å; F191-K194 PolarHBondContact O-N 3.03Å; K194-P196 WeakPolarHBondContact O-CD 3.49Å; K194-L224 WeakPolarHBondContact O-CD2 3.38Å
195	M	89.4	Confident	92.5	Very high	2 Å²	2	24.2 Å²	24.2	1%	0.01	13%	0.128	C	C	.	.	T	Hydrogen-bonded Turn	trans	-86.3	88.2	165.2	-75.2	-71.1	-78.7	0	0	106.2	F191 L192 M197 G227 M282 V285 L286 L289	F191-M195 WeakPolarHBondContact O-CB 3.31Å; F191-M195 PolarHBondContact O-N 3.49Å; L192-M195 CarbonylContact C-O 3.6Å; L192-M195 CarbonylContact O-C 3.53Å; M195-M197 VanDerWaalsContact C-N 3.34Å; M195-M197 PolarHBondContact O-N 3.48Å; M195-G227 VanDerWaalsContact CG-C 3.46Å; M195-M282 HydrophobicContact CE-CB 4.35Å; M195-M282 HydrophobicContact CE-SD 3.69Å; M195-M282 HydrophobicContact SD-SD 3.86Å; M195-V285 HydrophobicContact CE-CB 4.03Å; M195-V285 HydrophobicContact CE-CG1 3.65Å; M195-L286 HydrophobicContact CB-CD1 4.2Å; M195-L289 HydrophobicContact CE-CD1 4.43Å
196	P	81	Confident	92.4	Very high	3 Å²	3	24.6 Å²	24.6	2%	0.019	13%	0.13	C	C	.	.	T	Hydrogen-bonded Turn	trans	-55.4	94.2	-161.8	29.4	-42.3	0	0	0	110.6	K194 H201 L204 L224 V279	K194-P196 WeakPolarHBondContact O-CD 3.49Å; P196-H201 HydrophobicContact CB-CB 3.79Å; P196-L204 HydrophobicContact CB-CD1 3.96Å; P196-L204 HydrophobicContact CG-CD1 3.52Å; P196-L224 HydrophobicContact CG-CD2 4.26Å; P196-V279 HydrophobicContact CB-CG2 4.25Å; P196-V279 HydrophobicContact CG-CG2 4.02Å
197	M	91.2	Very high	92.5	Very high	10 Å²	10	23.5 Å²	23.5	5%	0.049	12%	0.122	C	C	.	.			trans	-65.5	146.8	170.6	-175	-178.1	-89.3	0	0	107.9	L192 M195 V200 H201 W249 I252 L286	L192-M197 HydrophobicContact CD1-CE 4.06Å; L192-M197 HydrophobicContact CD2-CE 3.64Å; L192-M197 HydrophobicContact CG-CE 4.33Å; L192-M197 PolarHBondContact O-N 3.08Å; L192-M197 VanDerWaalsContact O-N 3.17Å; M195-M197 VanDerWaalsContact C-N 3.34Å; M195-M197 PolarHBondContact O-N 3.48Å; M197-V200 CarbonylContact O-C 3.56Å; M197-V200 PolarHBondContact O-N 3.14Å; M197-H201 PolarHBondContact O-N 3.38Å; M197-W249 HydrophobicContact CE-CB 3.88Å; M197-W249 HydrophobicContact CE-CD2 3.77Å; M197-W249 HydrophobicContact CE-CE3 3.14Å; M197-W249 HydrophobicContact CE-CG 4.11Å; M197-W249 HydrophobicContact CE-CZ3 3.84Å; M197-W249 HydrophobicContact SD-CE3 3.45Å; M197-W249 HydrophobicContact SD-CZ3 3.6Å; M197-I252 HydrophobicContact CG-CG2 3.78Å; M197-I252 HydrophobicContact SD-CB 4.38Å; M197-I252 HydrophobicContact SD-CG2 3.81Å; M197-L286 HydrophobicContact CE-CD1 4.31Å; M197-L286 HydrophobicContact CE-CD2 3.77Å
198	F	87.4	Confident	92.5	Very high	51 Å²	51	23.5 Å²	23.5	22%	0.224	12%	0.122	C	C	.	.	T	Hydrogen-bonded Turn	trans	-50.7	146.9	165.7	-170.4	-108	0	0	0	110.3	V200 H201 I252 G256 L259 V260	F198-V200 VanDerWaalsContact C-N 3.32Å; F198-V200 PolarHBondContact O-N 3.35Å; F198-H201 AromaticContact CD2-CE1 3.9Å; F198-I252 HydrophobicContact CB-CG2 4.21Å; F198-G256 VanDerWaalsContact CB-CA 3.49Å; F198-G256 VanDerWaalsContact CD2-CA 3.42Å; F198-G256 WeakPolarHBondContact CD2-O 3.38Å; F198-L259 HydrophobicContact CE1-CD1 3.81Å; F198-L259 HydrophobicContact CE2-CB 3.97Å; F198-L259 HydrophobicContact CE2-CD1 4.29Å; F198-L259 HydrophobicContact CZ-CB 3.99Å; F198-L259 HydrophobicContact CZ-CD1 3.49Å; F198-L259 VanDerWaalsContact CZ-CD1 3.49Å; F198-L259 HydrophobicContact CZ-CG 4.4Å; F198-V260 HydrophobicContact CD2-CG2 3.75Å; F198-V260 HydrophobicContact CE2-CG2 3.99Å
199	L	93.2	Very high	92.4	Very high	119 Å²	119	24.1 Å²	24.1	62%	0.623	13%	0.126	S	C	*	.	T	Hydrogen-bonded Turn	trans	81.1	-46.2	-161.7	-48.3	170.1	0	0	0	115.5	H201	L199-H201 PolarHBondContact N-ND1 3.3Å
200	V	92.9	Very high	92.4	Very high	45 Å²	45	22.6 Å²	22.6	27%	0.273	12%	0.115	S	C	.	.	T	Hydrogen-bonded Turn	trans	-102.1	2	-174.9	-153.9	0	0	0	0	113.2	Y146 V193 M197 F198 L202 W203	Y146-V200 HydrophobicContact CD1-CG1 3.57Å; Y146-V200 HydrophobicContact CE1-CG1 3.83Å; V193-V200 HydrophobicContact CB-CG1 4.36Å; V193-V200 HydrophobicContact CG1-CG1 4.01Å; V193-V200 HydrophobicContact CG2-CG1 3.83Å; M197-V200 CarbonylContact O-C 3.56Å; M197-V200 PolarHBondContact O-N 3.14Å; F198-V200 VanDerWaalsContact C-N 3.32Å; F198-V200 PolarHBondContact O-N 3.35Å; V200-L202 VanDerWaalsContact C-N 3.32Å; V200-L202 PolarHBondContact O-N 3.45Å; V200-W203 PolarHBondContact O-NE1 3.3Å
201	H	94.1	Very high	92.4	Very high	18 Å²	18	22.4 Å²	22.4	8%	0.083	11%	0.113	C	C	.	.	T	Hydrogen-bonded Turn	trans	-72	-11	-177.4	68.6	-73.9	0	0	0	116.3	P196 M197 F198 L199 W203 L204 P205 V279	P196-H201 HydrophobicContact CB-CB 3.79Å; M197-H201 PolarHBondContact O-N 3.38Å; F198-H201 AromaticContact CD2-CE1 3.9Å; L199-H201 PolarHBondContact N-ND1 3.3Å; H201-W203 PolarHBondContact O-N 3.32Å; H201-W203 VanDerWaalsContact O-N 3.1Å; H201-L204 WeakPolarHBondContact O-CB 3.31Å; H201-L204 PolarHBondContact O-N 3.39Å; H201-P205 WeakPolarHBondContact O-CD 3.49Å; H201-V279 HydrophobicContact CB-CG1 3.89Å; H201-V279 HydrophobicContact CB-CG2 4.11Å
202	L	93.1	Very high	92.4	Very high	87 Å²	87	22.5 Å²	22.5	46%	0.455	11%	0.114	S	C	.	.	T	Hydrogen-bonded Turn	trans	-62.1	-23.6	-168.4	-68.1	175.6	0	0	0	114.8	V200 L204	V200-L202 VanDerWaalsContact C-N 3.32Å; V200-L202 PolarHBondContact O-N 3.45Å; L202-L204 VanDerWaalsContact C-N 3.27Å; L202-L204 PolarHBondContact O-N 3.03Å
203	W	94.4	Very high	92.3	Very high	4 Å²	4	22.5 Å²	22.5	2%	0.015	12%	0.115	C	C	.	.	H	α-helix	trans	-67	-31.4	175.6	67.8	-96.2	0	0	0	111.8	L143 Y146 V193 V200 H201 A207 L219 L224	L143-W203 HydrophobicContact CD1-CD2 4.31Å; L143-W203 HydrophobicContact CD1-CE3 3.38Å; L143-W203 HydrophobicContact CD1-CH2 4.25Å; L143-W203 HydrophobicContact CD1-CZ3 3.34Å; Y146-W203 HydrophobicContact CD2-CB 4.13Å; Y146-W203 HydrophobicContact CG-CB 4.21Å; Y146-W203 HydrophobicContact CG-CG 4.47Å; V193-W203 WeakPolarHBondContact O-CZ2 3.39Å; V193-W203 PolarHBondContact O-NE1 2.94Å; V200-W203 PolarHBondContact O-NE1 3.3Å; H201-W203 PolarHBondContact O-N 3.32Å; H201-W203 VanDerWaalsContact O-N 3.1Å; W203-A207 HydrophobicContact CE3-CB 4.21Å; W203-A207 VanDerWaalsContact O-CB 3.25Å; W203-A207 WeakPolarHBondContact O-CB 3.42Å; W203-A207 PolarHBondContact O-N 3.39Å; W203-L219 HydrophobicContact CZ3-CD2 4.44Å; W203-L224 HydrophobicContact CH2-CD2 3.95Å; W203-L224 HydrophobicContact CZ2-CD2 4.31Å
204	L	93	Very high	92.3	Very high	0 Å²	0	22.2 Å²	22.2	0%	0	11%	0.113	C	C	.	.	H	α-helix	trans	-68.9	-53.5	-171	-175.9	166.5	0	0	0	112.1	P196 H201 L202 K206 A207 H208 L224 A275 V279	P196-L204 HydrophobicContact CB-CD1 3.96Å; P196-L204 HydrophobicContact CG-CD1 3.52Å; H201-L204 WeakPolarHBondContact O-CB 3.31Å; H201-L204 PolarHBondContact O-N 3.39Å; L202-L204 VanDerWaalsContact C-N 3.27Å; L202-L204 PolarHBondContact O-N 3.03Å; L204-K206 VanDerWaalsContact C-N 3.27Å; L204-K206 PolarHBondContact O-N 2.64Å; L204-A207 PolarHBondContact O-N 2.92Å; L204-H208 WeakPolarHBondContact CD2-CD2 3.33Å; L204-H208 PolarHBondContact O-CD2 3.31Å; L204-H208 VanDerWaalsContact O-CD2 3.28Å; L204-H208 PolarHBondContact O-N 3.34Å; L204-L224 HydrophobicContact CD1-CD1 4Å; L204-L224 HydrophobicContact CD1-CD2 3.49Å; L204-L224 VanDerWaalsContact CD1-CD2 3.49Å; L204-L224 HydrophobicContact CD1-CG 4.39Å; L204-L224 HydrophobicContact CG-CD2 4.47Å; L204-A275 HydrophobicContact CD2-CB 3.74Å; L204-A275 WeakPolarHBondContact CD2-O 3.45Å; L204-V279 HydrophobicContact CD1-CG2 3.87Å; L204-V279 HydrophobicContact CD2-CG2 4.09Å; L204-V279 HydrophobicContact CG-CG2 4.46Å
205	P	93.2	Very high	92.4	Very high	8 Å²	8	22.3 Å²	22.3	5%	0.052	12%	0.115	C	C	.	.	H	α-helix	trans	-55.8	-41.8	177.9	-26.6	34.4	0	0	0	112.7	H201 V209 Y276	H201-P205 WeakPolarHBondContact O-CD 3.49Å; P205-V209 VanDerWaalsContact O-CB 3.3Å; P205-V209 WeakPolarHBondContact O-CB 3.37Å; P205-V209 WeakPolarHBondContact O-CG2 3.49Å; P205-V209 PolarHBondContact O-N 3.16Å; P205-Y276 HydrophobicContact CB-CE1 4.31Å; P205-Y276 HydrophobicContact CB-CE2 3.98Å; P205-Y276 HydrophobicContact CG-CD1 3.94Å; P205-Y276 HydrophobicContact CG-CD2 4.45Å; P205-Y276 HydrophobicContact CG-CE1 3.46Å; P205-Y276 VanDerWaalsContact CG-CE1 3.46Å; P205-Y276 HydrophobicContact CG-CE2 4Å; P205-Y276 HydrophobicContact CG-CG 4.41Å; P205-Y276 VanDerWaalsContact CG-CZ 3.48Å
206	K	93	Very high	92.7	Very high	87 Å²	87	22.2 Å²	22.2	38%	0.378	11%	0.114	S	C	.	.	H	α-helix	trans	-65.9	-45.3	178	-65.3	-173.5	-179.9	-175.3	0	111.9	A139 Y142 L204 H208 E210	A139-K206 HydrophobicContact CB-CB 4.21Å; Y142-K206 HydrophobicContact CD2-CD 3.56Å; Y142-K206 HydrophobicContact CE2-CD 3.56Å; L204-K206 VanDerWaalsContact C-N 3.27Å; L204-K206 PolarHBondContact O-N 2.64Å; K206-H208 PolarHBondContact O-N 3.06Å; K206-E210 PolarHBondContact O-N 3.41Å
207	A	94.7	Very high	93.5	Very high	0 Å²	0	22.1 Å²	22.1	0%	0	11%	0.113	C	C	.	.	H	α-helix	trans	-62.3	-44.3	179.1	0	0	0	0	0	112.1	W203 L204 A211 L219	W203-A207 HydrophobicContact CE3-CB 4.21Å; W203-A207 VanDerWaalsContact O-CB 3.25Å; W203-A207 WeakPolarHBondContact O-CB 3.42Å; W203-A207 PolarHBondContact O-N 3.39Å; L204-A207 PolarHBondContact O-N 2.92Å; A207-A211 WeakPolarHBondContact O-CB 3.49Å; A207-A211 PolarHBondContact O-N 3Å; A207-L219 HydrophobicContact CB-CD1 4.05Å
208	H	94.2	Very high	93.7	Very high	0 Å²	0	21.7 Å²	21.7	0%	0	11%	0.111	C	C	.	.	H	α-helix	trans	-69.7	-39.4	-180	-84	-79.9	0	0	0	114.1	L204 K206 E210 S216 L219 A220 A275 F315	L204-H208 WeakPolarHBondContact CD2-CD2 3.33Å; L204-H208 PolarHBondContact O-CD2 3.31Å; L204-H208 VanDerWaalsContact O-CD2 3.28Å; L204-H208 PolarHBondContact O-N 3.34Å; K206-H208 PolarHBondContact O-N 3.06Å; H208-E210 VanDerWaalsContact C-N 3.32Å; H208-S216 PolarHBondContact CE1-O 3.25Å; H208-S216 VanDerWaalsContact CE1-O 3.27Å; H208-S216 PolarHBondContact ND1-O 3.17Å; H208-S216 PolarHBondContact O-OG 2.96Å; H208-S216 VanDerWaalsContact O-OG 3.12Å; H208-L219 WeakPolarHBondContact CE1-CB 3.39Å; H208-A220 PolarHBondContact CE1-N 3.4Å; H208-A220 VanDerWaalsContact CE1-N 3.31Å; H208-A275 HydrophobicContact CB-CB 3.86Å; H208-F315 HydrophobicContact CB-CE1 4.09Å; H208-F315 HydrophobicContact CB-CZ 4.01Å; H208-F315 AromaticContact CE1-CE2 3.8Å; H208-F315 AromaticContact CE1-CZ 3.92Å; H208-F315 AromaticContact CG-CZ 3.7Å; H208-F315 AromaticContact ND1-CE1 3.81Å; H208-F315 AromaticContact ND1-CE2 3.51Å; H208-F315 AromaticContact ND1-CZ 3.23Å; H208-F315 WeakPolarHBondContact ND1-CZ 3.49Å
209	V	92.8	Very high	94.1	Very high	14 Å²	14	19.4 Å²	19.4	9%	0.085	10%	0.101	C	C	.	.	H	α-helix	trans	-68.5	-37.6	-176.3	172.3	0	0	0	0	110.7	P205 K271 A272 R328	P205-V209 VanDerWaalsContact O-CB 3.3Å; P205-V209 WeakPolarHBondContact O-CB 3.37Å; P205-V209 WeakPolarHBondContact O-CG2 3.49Å; P205-V209 PolarHBondContact O-N 3.16Å; V209-K271 HydrophobicContact CG2-CB 4.08Å; V209-A272 HydrophobicContact CG2-CB 3.78Å; V209-R328 PolarHBondContact O-NH1 3.28Å
210	E	93.1	Very high	94.2	Very high	5 Å²	5	13.7 Å²	13.7	2%	0.023	7%	0.072	C	C	.	.	H	α-helix	trans	-91.4	-21.7	-177.2	-63.9	-47.7	124	0	0	115.2	G131 Q133 E135 R136 A139 K206 H208 R328	G131-E210 VanDerWaalsContact CA-O 3.28Å; G131-E210 WeakPolarHBondContact CA-O 3.28Å; Q133-E210 WeakPolarHBondContact CB-OE2 2.98Å; Q133-E210 VanDerWaalsContact CG-OE2 3.32Å; Q133-E210 WeakPolarHBondContact CG-OE2 3.21Å; Q133-E210 PolarHBondContact OE1-OE1 2.96Å; E135-E210 HydrophobicContact CB-CG 4.07Å; R136-E210 HydrophobicContact CB-CB 4.2Å; A139-E210 HydrophobicContact CB-CB 4.04Å; A139-E210 HydrophobicContact CB-CG 4.18Å; K206-E210 PolarHBondContact O-N 3.41Å; H208-E210 VanDerWaalsContact C-N 3.32Å; E210-R328 IonicContact OE1-CZ 3.71Å; E210-R328 IonicContact OE1-NH1 3.48Å; E210-R328 PolarHBondContact OE1-NH1 3.14Å; E210-R328 IonicContact OE1-NH2 2.82Å; E210-R328 PolarHBondContact OE1-NH2 3.11Å; E210-R328 IonicContact OE2-NH1 3.23Å
211	A	94	Very high	94.3	Very high	0 Å²	0	11.6 Å²	11.6	0%	0	6%	0.059	C	C	.	.	S	Bend	trans	-62.2	149.5	175	0	0	0	0	0	111.9	I127 A207 L219 K271	I127-A211 HydrophobicContact CG1-CB 4.06Å; A207-A211 WeakPolarHBondContact O-CB 3.49Å; A207-A211 PolarHBondContact O-N 3Å; A211-L219 HydrophobicContact CB-CD1 4.4Å; A211-K271 PolarHBondContact O-NZ 3.33Å
212	P	93.9	Very high	94.4	Very high	3 Å²	3	10.8 Å²	10.8	2%	0.019	6%	0.055	C	C	.	.			trans	-59.1	167	160.1	30.5	-36.1	0	0	0	109.8	L126 W130 S214 G215 S216	L126-P212 WeakPolarHBondContact O-CD 3.29Å; L126-P212 WeakPolarHBondContact O-CG 3.09Å; W130-P212 HydrophobicContact CB-CB 4.12Å; W130-P212 HydrophobicContact CB-CG 4.05Å; P212-S214 PolarHBondContact O-N 2.98Å; P212-G215 PolarHBondContact O-N 2.82Å; P212-G215 VanDerWaalsContact O-N 3.09Å; P212-S216 PolarHBondContact O-N 3.44Å; P212-S216 PolarHBondContact O-OG 2.9Å
213	V	94.2	Very high	94.5	Very high	6 Å²	6	6.8 Å²	6.8	4%	0.036	3%	0.034	C	C	.	.	H	α-helix	trans	-53.6	-45.6	179	-164	0	0	0	0	111.4	A75 G215 S216 M217 N319	A75-V213 HydrophobicContact CB-CG1 3.99Å; V213-G215 PolarHBondContact O-N 3.34Å; V213-S216 WeakPolarHBondContact O-CB 3.47Å; V213-S216 PolarHBondContact O-N 3.38Å; V213-M217 HydrophobicContact CG1-CG 4.45Å; V213-M217 HydrophobicContact CG1-SD 4.11Å; V213-M217 WeakPolarHBondContact O-CB 3.39Å; V213-M217 VanDerWaalsContact O-CG 3.26Å; V213-M217 WeakPolarHBondContact O-CG 3.14Å; V213-M217 PolarHBondContact O-N 3.47Å; V213-N319 HydrophobicContact CB-CB 4.26Å; V213-N319 HydrophobicContact CG1-CB 3.66Å; V213-N319 HydrophobicContact CG2-CB 3.59Å; V213-N319 VanDerWaalsContact CG2-ND2 3.34Å; V213-N319 WeakPolarHBondContact CG2-ND2 3.33Å; V213-N319 WeakPolarHBondContact CG2-OD1 3.39Å
214	S	93.9	Very high	94.4	Very high	1 Å²	1	6.6 Å²	6.6	1%	0.007	3%	0.034	C	C	.	.	H	α-helix	trans	-57.2	-48.1	176.7	45.4	0	0	0	0	112.2	M72 F89 P212 M217 I218	M72-S214 VanDerWaalsContact CE-CB 3.46Å; F89-S214 WeakPolarHBondContact CE2-OG 3.45Å; P212-S214 PolarHBondContact O-N 2.98Å; S214-M217 PolarHBondContact O-N 3.26Å; S214-I218 WeakPolarHBondContact O-CD1 3.26Å; S214-I218 WeakPolarHBondContact O-CG1 3.35Å; S214-I218 PolarHBondContact O-N 3.26Å; S214-I218 VanDerWaalsContact O-N 3.11Å
215	G	94.6	Very high	94.6	Very high	5 Å²	5	6.6 Å²	6.6	5%	0.052	3%	0.034	C	C	.	.	H	α-helix	trans	-63.3	-42.9	175.5	0	0	0	0	0	112.3	P212 V213 M217 I218 L219	P212-G215 PolarHBondContact O-N 2.82Å; P212-G215 VanDerWaalsContact O-N 3.09Å; V213-G215 PolarHBondContact O-N 3.34Å; G215-M217 VanDerWaalsContact C-N 3.35Å; G215-M217 PolarHBondContact O-N 3.47Å; G215-I218 PolarHBondContact O-N 3.14Å; G215-L219 VanDerWaalsContact O-CB 3.31Å; G215-L219 WeakPolarHBondContact O-CB 3.36Å; G215-L219 VanDerWaalsContact O-CG 3.24Å; G215-L219 WeakPolarHBondContact O-CG 3.48Å; G215-L219 PolarHBondContact O-N 3.3Å
216	S	95.7	Very high	94.7	Very high	1 Å²	1	6.2 Å²	6.2	1%	0.007	3%	0.031	C	C	.	.	H	α-helix	trans	-61.1	-42.9	177.4	-55.8	0	0	0	0	111.8	H208 P212 V213 A220	H208-S216 PolarHBondContact CE1-O 3.25Å; H208-S216 VanDerWaalsContact CE1-O 3.27Å; H208-S216 PolarHBondContact ND1-O 3.17Å; H208-S216 PolarHBondContact O-OG 2.96Å; H208-S216 VanDerWaalsContact O-OG 3.12Å; P212-S216 PolarHBondContact O-N 3.44Å; P212-S216 PolarHBondContact O-OG 2.9Å; V213-S216 WeakPolarHBondContact O-CB 3.47Å; V213-S216 PolarHBondContact O-N 3.38Å; S216-A220 VanDerWaalsContact O-CB 3.3Å; S216-A220 WeakPolarHBondContact O-CB 3.27Å; S216-A220 PolarHBondContact O-N 3.43Å
217	M	96.7	Very high	94.8	Very high	0 Å²	0	2.1 Å²	2.1	0%	0	1%	0.013	C	C	.	.	H	α-helix	trans	-65.7	-43	179.1	-72.1	174.2	73.3	0	0	112.2	I68 L71 A75 V213 S214 G215 G221 H428	I68-M217 HydrophobicContact CG2-CB 4.41Å; L71-M217 HydrophobicContact CB-CE 3.81Å; A75-M217 HydrophobicContact CB-SD 3.65Å; V213-M217 HydrophobicContact CG1-CG 4.45Å; V213-M217 HydrophobicContact CG1-SD 4.11Å; V213-M217 WeakPolarHBondContact O-CB 3.39Å; V213-M217 VanDerWaalsContact O-CG 3.26Å; V213-M217 WeakPolarHBondContact O-CG 3.14Å; V213-M217 PolarHBondContact O-N 3.47Å; S214-M217 PolarHBondContact O-N 3.26Å; G215-M217 VanDerWaalsContact C-N 3.35Å; G215-M217 PolarHBondContact O-N 3.47Å; M217-G221 VanDerWaalsContact O-CA 3.3Å; M217-G221 WeakPolarHBondContact O-CA 3.17Å; M217-G221 PolarHBondContact O-N 2.85Å; M217-H428 WeakPolarHBondContact CE-NE2 3.41Å
218	I	96.6	Very high	94.8	Very high	1 Å²	1	2.1 Å²	2.1	1%	0.005	1%	0.013	C	C	.	.	H	α-helix	trans	-71.8	-42.1	179.2	-62.2	156.1	0	0	0	111.5	M72 L96 L100 L126 S214 G215 A220 G221 I222 M223	M72-I218 HydrophobicContact CE-CD1 3.09Å; M72-I218 HydrophobicContact CE-CG1 3.88Å; M72-I218 HydrophobicContact SD-CD1 3.53Å; M72-I218 VanDerWaalsContact SD-CD1 3.53Å; M72-I218 HydrophobicContact SD-CG1 3.85Å; L96-I218 HydrophobicContact CD2-CB 4.47Å; L96-I218 HydrophobicContact CD2-CD1 3.33Å; L96-I218 HydrophobicContact CD2-CG1 4.24Å; L96-I218 HydrophobicContact CD2-CG2 3.81Å; L100-I218 HydrophobicContact CD1-CG2 4.48Å; L126-I218 HydrophobicContact CD1-CD1 3.6Å; S214-I218 WeakPolarHBondContact O-CD1 3.26Å; S214-I218 WeakPolarHBondContact O-CG1 3.35Å; S214-I218 PolarHBondContact O-N 3.26Å; S214-I218 VanDerWaalsContact O-N 3.11Å; G215-I218 PolarHBondContact O-N 3.14Å; I218-A220 VanDerWaalsContact C-N 3.31Å; I218-A220 PolarHBondContact O-N 3.37Å; I218-G221 PolarHBondContact O-N 3.06Å; I218-I222 HydrophobicContact CG2-CD1 4.42Å; I218-I222 PolarHBondContact O-N 3.18Å; I218-M223 HydrophobicContact CG2-CG 4.01Å; I218-M223 PolarHBondContact O-N 3.27Å; I218-M223 VanDerWaalsContact O-N 3.08Å
219	L	95.7	Very high	94.8	Very high	3 Å²	3	2.1 Å²	2.1	2%	0.016	1%	0.013	C	C	.	.	I	π-helix	trans	-56.2	-50.5	176.5	-76.9	169.2	0	0	0	109.9	I127 L143 W203 A207 H208 A211 G215 M223 L224	I127-L219 HydrophobicContact CD1-CD1 4.34Å; L143-L219 HydrophobicContact CD1-CD2 4.49Å; W203-L219 HydrophobicContact CZ3-CD2 4.44Å; A207-L219 HydrophobicContact CB-CD1 4.05Å; H208-L219 WeakPolarHBondContact CE1-CB 3.39Å; A211-L219 HydrophobicContact CB-CD1 4.4Å; G215-L219 VanDerWaalsContact O-CB 3.31Å; G215-L219 WeakPolarHBondContact O-CB 3.36Å; G215-L219 VanDerWaalsContact O-CG 3.24Å; G215-L219 WeakPolarHBondContact O-CG 3.48Å; G215-L219 PolarHBondContact O-N 3.3Å; L219-M223 HydrophobicContact CD2-CB 4.19Å; L219-M223 HydrophobicContact CD2-CG 4.12Å; L219-M223 PolarHBondContact O-N 3.21Å; L219-L224 WeakPolarHBondContact O-CG 3.09Å; L219-L224 PolarHBondContact O-N 3.11Å
220	A	94.9	Very high	94.9	Very high	0 Å²	0	1.4 Å²	1.4	0%	0	1%	0.009	C	C	.	.	I	π-helix	trans	-70.5	-45.4	-178.3	0	0	0	0	0	110.7	H208 S216 I218 K225 F315	H208-A220 PolarHBondContact CE1-N 3.4Å; H208-A220 VanDerWaalsContact CE1-N 3.31Å; S216-A220 VanDerWaalsContact O-CB 3.3Å; S216-A220 WeakPolarHBondContact O-CB 3.27Å; S216-A220 PolarHBondContact O-N 3.43Å; I218-A220 VanDerWaalsContact C-N 3.31Å; I218-A220 PolarHBondContact O-N 3.37Å; A220-K225 PolarHBondContact O-NZ 3.03Å; A220-F315 HydrophobicContact CB-CD2 3.75Å; A220-F315 HydrophobicContact CB-CE2 3.61Å
221	G	94	Very high	95	Very high	0 Å²	0	1.3 Å²	1.3	0%	0	1%	0.009	C	C	.	.	I	π-helix	trans	-66.6	-49.4	-172.8	0	0	0	0	0	113.6	L64 I68 M217 I218 K225	L64-G221 WeakPolarHBondContact CD2-O 3.33Å; I68-G221 VanDerWaalsContact CD1-CA 3.46Å; M217-G221 VanDerWaalsContact O-CA 3.3Å; M217-G221 WeakPolarHBondContact O-CA 3.17Å; M217-G221 PolarHBondContact O-N 2.85Å; I218-G221 PolarHBondContact O-N 3.06Å; G221-K225 WeakPolarHBondContact O-CD 3.32Å; G221-K225 WeakPolarHBondContact O-CE 3.19Å
222	I	96.4	Very high	95	Very high	1 Å²	1	2.1 Å²	2.1	1%	0.005	1%	0.013	C	C	.	.	I	π-helix	trans	-128.2	-42.2	-163.4	-51	160.5	0	0	0	112.2	S65 I68 L100 F104 I218 L224 K225 L226	S65-I222 VanDerWaalsContact CA-CD1 3.49Å; I68-I222 HydrophobicContact CB-CD1 4.19Å; I68-I222 HydrophobicContact CD1-CG1 4.24Å; I68-I222 HydrophobicContact CG2-CD1 4.37Å; L100-I222 HydrophobicContact CD1-CB 4.49Å; L100-I222 HydrophobicContact CD1-CD1 3.82Å; L100-I222 HydrophobicContact CD1-CG2 4.06Å; L100-I222 HydrophobicContact CD2-CG2 3.8Å; L100-I222 HydrophobicContact CG-CG2 4.45Å; F104-I222 HydrophobicContact CE2-CG2 3.66Å; F104-I222 HydrophobicContact CZ-CG2 3.72Å; I218-I222 HydrophobicContact CG2-CD1 4.42Å; I218-I222 PolarHBondContact O-N 3.18Å; I222-L224 VanDerWaalsContact C-N 3.34Å; I222-L224 PolarHBondContact O-N 3.27Å; I222-K225 CarbonylContact O-C 3.55Å; I222-K225 WeakPolarHBondContact O-CA 3.28Å; I222-K225 WeakPolarHBondContact O-CB 3.34Å; I222-K225 PolarHBondContact O-N 3.5Å; I222-L226 PolarHBondContact O-N 3.45Å
223	M	95.1	Very high	95	Very high	4 Å²	4	3 Å²	3	2%	0.02	2%	0.016	C	C	.	.	I	π-helix	trans	-64.9	-36.5	-170.9	-63.3	-65.2	-68.4	0	0	113.1	L100 L120 T123 I218 L219 K225 L226	L100-M223 HydrophobicContact CD2-SD 4.21Å; L120-M223 HydrophobicContact CD2-CE 4.05Å; T123-M223 HydrophobicContact CG2-CE 3.89Å; T123-M223 HydrophobicContact CG2-CG 4.16Å; T123-M223 HydrophobicContact CG2-SD 3.86Å; I218-M223 HydrophobicContact CG2-CG 4.01Å; I218-M223 PolarHBondContact O-N 3.27Å; I218-M223 VanDerWaalsContact O-N 3.08Å; L219-M223 HydrophobicContact CD2-CB 4.19Å; L219-M223 HydrophobicContact CD2-CG 4.12Å; L219-M223 PolarHBondContact O-N 3.21Å; M223-K225 VanDerWaalsContact C-N 3.29Å; M223-L226 HydrophobicContact CE-CD1 4.1Å; M223-L226 WeakPolarHBondContact O-CB 3.35Å; M223-L226 PolarHBondContact O-N 2.91Å; M223-L226 HydrophobicContact SD-CD1 3.65Å
224	L	94	Very high	94.9	Very high	0 Å²	0	2.7 Å²	2.7	0%	0	1%	0.014	C	C	.	.	H	α-helix	trans	-63.3	-40.3	171.6	-56	175.7	0	0	0	110.6	K194 P196 W203 L204 L219 I222 L226 G227 G228 M282	K194-L224 WeakPolarHBondContact O-CD2 3.38Å; P196-L224 HydrophobicContact CG-CD2 4.26Å; W203-L224 HydrophobicContact CH2-CD2 3.95Å; W203-L224 HydrophobicContact CZ2-CD2 4.31Å; L204-L224 HydrophobicContact CD1-CD1 4Å; L204-L224 HydrophobicContact CD1-CD2 3.49Å; L204-L224 VanDerWaalsContact CD1-CD2 3.49Å; L204-L224 HydrophobicContact CD1-CG 4.39Å; L204-L224 HydrophobicContact CG-CD2 4.47Å; L219-L224 WeakPolarHBondContact O-CG 3.09Å; L219-L224 PolarHBondContact O-N 3.11Å; I222-L224 VanDerWaalsContact C-N 3.34Å; I222-L224 PolarHBondContact O-N 3.27Å; L224-L226 VanDerWaalsContact C-N 3.3Å; L224-L226 PolarHBondContact O-N 3.28Å; L224-G227 PolarHBondContact O-N 2.96Å; L224-G228 PolarHBondContact O-N 3.27Å; L224-M282 HydrophobicContact CD1-CG 4.37Å
225	K	96.3	Very high	94.9	Very high	0 Å²	0	2.8 Å²	2.8	0%	0	1%	0.014	C	C	.	.	H	α-helix	trans	-70.2	-26	-177.1	-72.3	61.8	165.7	179.5	0	112.5	L61 A220 G221 I222 M223 G227 G228 Y229 M282 M304 G308	L61-K225 HydrophobicContact CD2-CB 4.17Å; L61-K225 HydrophobicContact CD2-CG 4.46Å; A220-K225 PolarHBondContact O-NZ 3.03Å; G221-K225 WeakPolarHBondContact O-CD 3.32Å; G221-K225 WeakPolarHBondContact O-CE 3.19Å; I222-K225 CarbonylContact O-C 3.55Å; I222-K225 WeakPolarHBondContact O-CA 3.28Å; I222-K225 WeakPolarHBondContact O-CB 3.34Å; I222-K225 PolarHBondContact O-N 3.5Å; M223-K225 VanDerWaalsContact C-N 3.29Å; K225-G227 PolarHBondContact O-N 3.22Å; K225-G228 PolarHBondContact O-N 2.62Å; K225-G228 VanDerWaalsContact O-N 3.16Å; K225-Y229 WeakPolarHBondContact O-CB 3.41Å; K225-Y229 PolarHBondContact O-N 3.14Å; K225-M282 HydrophobicContact CD-CE 3.91Å; K225-M282 VanDerWaalsContact NZ-CE 3.26Å; K225-M304 HydrophobicContact CB-SD 4.41Å; K225-M304 WeakPolarHBondContact CE-O 3.38Å; K225-M304 HydrophobicContact CG-CB 3.88Å; K225-M304 HydrophobicContact CG-CG 4.1Å; K225-M304 HydrophobicContact CG-SD 4.29Å; K225-G308 VanDerWaalsContact NZ-CA 3.33Å
226	L	94.7	Very high	94.6	Very high	0 Å²	0	3.8 Å²	3.8	0%	0	2%	0.021	C	C	.	.	H	α-helix	trans	-56.6	-38.8	169.7	-71.8	173.1	0	0	0	111.6	L100 T103 F104 F116 I222 M223 L224 G230	L100-L226 HydrophobicContact CD2-CD1 3.72Å; L100-L226 HydrophobicContact CD2-CD2 4.11Å; L100-L226 HydrophobicContact CD2-CG 4.21Å; T103-L226 HydrophobicContact CG2-CD2 4.27Å; T103-L226 VanDerWaalsContact OG1-CD2 3.26Å; T103-L226 WeakPolarHBondContact OG1-CD2 3.39Å; F104-L226 HydrophobicContact CD1-CD2 4.31Å; F104-L226 HydrophobicContact CE1-CD2 3.55Å; F104-L226 HydrophobicContact CE1-CG 4.43Å; F104-L226 HydrophobicContact CE2-CD2 3.99Å; F104-L226 HydrophobicContact CZ-CD2 3.36Å; F104-L226 HydrophobicContact CZ-CG 4.04Å; F116-L226 HydrophobicContact CD2-CB 4.03Å; F116-L226 HydrophobicContact CE2-CB 4.02Å; I222-L226 PolarHBondContact O-N 3.45Å; M223-L226 HydrophobicContact CE-CD1 4.1Å; M223-L226 WeakPolarHBondContact O-CB 3.35Å; M223-L226 PolarHBondContact O-N 2.91Å; M223-L226 HydrophobicContact SD-CD1 3.65Å; L224-L226 VanDerWaalsContact C-N 3.3Å; L224-L226 PolarHBondContact O-N 3.28Å; L226-G230 PolarHBondContact O-N 3.15Å
227	G	94.6	Very high	94.4	Very high	0 Å²	0	3.8 Å²	3.8	0%	0	2%	0.02	C	C	.	.	H	α-helix	trans	-66	-45.1	175	0	0	0	0	0	111.7	M195 L224 K225 G230 M231	M195-G227 VanDerWaalsContact CG-C 3.46Å; L224-G227 PolarHBondContact O-N 2.96Å; K225-G227 PolarHBondContact O-N 3.22Å; G227-G230 PolarHBondContact O-N 3.46Å; G227-M231 VanDerWaalsContact O-CG 3.31Å; G227-M231 WeakPolarHBondContact O-CG 3.43Å; G227-M231 PolarHBondContact O-N 2.75Å
228	G	94.9	Very high	94.2	Very high	0 Å²	0	3.8 Å²	3.8	0%	0	2%	0.02	C	C	.	.	H	α-helix	trans	-63.2	-43.3	177.1	0	0	0	0	0	112.9	L224 K225 M231 L232	L224-G228 PolarHBondContact O-N 3.27Å; K225-G228 PolarHBondContact O-N 2.62Å; K225-G228 VanDerWaalsContact O-N 3.16Å; G228-M231 WeakPolarHBondContact O-CB 3.28Å; G228-M231 PolarHBondContact O-N 3.07Å; G228-L232 WeakPolarHBondContact O-CD1 3.36Å; G228-L232 VanDerWaalsContact O-CG 3.28Å; G228-L232 WeakPolarHBondContact O-CG 3.43Å; G228-L232 PolarHBondContact O-N 3.15Å
229	Y	95.5	Very high	94	Very high	0 Å²	0	7.2 Å²	7.2	0%	0	4%	0.036	C	C	.	.	H	α-helix	trans	-59.7	-46.1	173.5	178.1	-102.5	0	0	0	112.1	L57 L61 F104 F112 K225 M231 L232 R233	L57-Y229 HydrophobicContact CD2-CD2 4.18Å; L57-Y229 HydrophobicContact CD2-CE2 4.39Å; L61-Y229 HydrophobicContact CD1-CD2 3.58Å; L61-Y229 HydrophobicContact CD1-CG 3.93Å; F104-Y229 AromaticContact CD1-CD1 3.83Å; F104-Y229 HydrophobicContact CD1-CD1 3.83Å; F104-Y229 HydrophobicContact CD1-CD2 4.12Å; F104-Y229 HydrophobicContact CD1-CE1 4.18Å; F104-Y229 HydrophobicContact CD1-CE2 4.46Å; F104-Y229 AromaticContact CD1-CG 3.8Å; F104-Y229 HydrophobicContact CD1-CG 3.8Å; F104-Y229 HydrophobicContact CE1-CD1 4.23Å; F104-Y229 HydrophobicContact CE1-CG 4Å; F104-Y229 PolarHBondContact O-OH 3.31Å; F112-Y229 HydrophobicContact CD2-CD1 4.35Å; F112-Y229 AromaticContact CD2-CE1 4Å; F112-Y229 HydrophobicContact CD2-CE1 4Å; F112-Y229 AromaticContact CE2-CD1 3.55Å; F112-Y229 HydrophobicContact CE2-CD1 3.55Å; F112-Y229 AromaticContact CE2-CE1 3.66Å; F112-Y229 HydrophobicContact CE2-CE1 3.66Å; F112-Y229 HydrophobicContact CZ-CD1 4.07Å; F112-Y229 HydrophobicContact CZ-CE1 4.47Å; K225-Y229 WeakPolarHBondContact O-CB 3.41Å; K225-Y229 PolarHBondContact O-N 3.14Å; Y229-M231 PolarHBondContact O-N 3.41Å; Y229-L232 PolarHBondContact O-N 2.89Å; Y229-R233 HydrophobicContact CE1-CG 4.08Å; Y229-R233 HydrophobicContact CE2-CG 4.17Å; Y229-R233 WeakPolarHBondContact O-CG 3.17Å; Y229-R233 PolarHBondContact O-N 3.41Å; Y229-R233 VanDerWaalsContact O-N 3.09Å; Y229-R233 PolarHBondContact OH-NE 2.88Å; Y229-R233 PolarHBondContact OH-NH2 3.22Å
230	G	95.1	Very high	93.8	Very high	0 Å²	0	10.2 Å²	10.2	0%	0	5%	0.052	C	C	.	.	H	α-helix	trans	-59.8	-44.5	175.6	0	0	0	0	0	112.6	F191 L226 G227 L232 R233 V234	F191-G230 VanDerWaalsContact CE1-CA 3.49Å; L226-G230 PolarHBondContact O-N 3.15Å; G227-G230 PolarHBondContact O-N 3.46Å; G230-L232 PolarHBondContact O-N 3.38Å; G230-R233 PolarHBondContact O-N 3.12Å; G230-V234 WeakPolarHBondContact O-CB 3.39Å; G230-V234 WeakPolarHBondContact O-CG2 3.26Å; G230-V234 PolarHBondContact O-N 3.31Å
231	M	94.7	Very high	93.6	Very high	3 Å²	3	10.2 Å²	10.2	2%	0.015	5%	0.052	C	C	.	.	H	α-helix	trans	-56.8	-50.4	173.7	-70.5	-67.9	-96.3	0	0	111.1	L188 F191 L192 G227 G228 Y229 R233 V234 I235 L290	L188-M231 HydrophobicContact CB-SD 4.45Å; L188-M231 HydrophobicContact CD2-CE 3.85Å; L188-M231 HydrophobicContact CD2-SD 3.31Å; L188-M231 WeakPolarHBondContact CD2-SD 3.24Å; L188-M231 HydrophobicContact CG-SD 4.43Å; F191-M231 HydrophobicContact CB-CG 3.51Å; F191-M231 HydrophobicContact CB-SD 3.47Å; F191-M231 WeakPolarHBondContact CB-SD 3.31Å; F191-M231 HydrophobicContact CD2-CG 4.25Å; F191-M231 HydrophobicContact CD2-SD 3.83Å; F191-M231 HydrophobicContact CG-CG 4.11Å; F191-M231 HydrophobicContact CG-SD 4.08Å; L192-M231 HydrophobicContact CD2-CE 3.53Å; L192-M231 HydrophobicContact CG-CE 4.25Å; G227-M231 VanDerWaalsContact O-CG 3.31Å; G227-M231 WeakPolarHBondContact O-CG 3.43Å; G227-M231 PolarHBondContact O-N 2.75Å; G228-M231 WeakPolarHBondContact O-CB 3.28Å; G228-M231 PolarHBondContact O-N 3.07Å; Y229-M231 PolarHBondContact O-N 3.41Å; M231-R233 VanDerWaalsContact C-N 3.28Å; M231-R233 PolarHBondContact O-N 3.4Å; M231-V234 PolarHBondContact O-N 3.31Å; M231-V234 VanDerWaalsContact O-N 3.16Å; M231-I235 HydrophobicContact CB-CD1 3.99Å; M231-I235 HydrophobicContact CE-CD1 4.44Å; M231-I235 WeakPolarHBondContact O-CB 3.46Å; M231-I235 WeakPolarHBondContact O-CD1 3.43Å; M231-I235 WeakPolarHBondContact O-CG1 3.42Å; M231-I235 PolarHBondContact O-N 3.18Å; M231-L290 HydrophobicContact CE-CD2 3.98Å
232	L	94.2	Very high	93.6	Very high	17 Å²	17	10.2 Å²	10.2	9%	0.089	5%	0.052	C	C	.	.	H	α-helix	trans	-57.7	-39.9	-178.7	-73.8	158.6	0	0	0	113.2	L57 G228 Y229 G230 L289 L297 M304 W445	L57-L232 HydrophobicContact CD2-CD1 4.2Å; G228-L232 WeakPolarHBondContact O-CD1 3.36Å; G228-L232 VanDerWaalsContact O-CG 3.28Å; G228-L232 WeakPolarHBondContact O-CG 3.43Å; G228-L232 PolarHBondContact O-N 3.15Å; Y229-L232 PolarHBondContact O-N 2.89Å; G230-L232 PolarHBondContact O-N 3.38Å; L232-L289 HydrophobicContact CD1-CD2 4.21Å; L232-L289 HydrophobicContact CD2-CD2 3.24Å; L232-L289 HydrophobicContact CG-CD2 3.61Å; L232-L297 HydrophobicContact CD2-CD2 3.64Å; L232-M304 HydrophobicContact CD1-CE 3.57Å; L232-W445 HydrophobicContact CD1-CH2 3.3Å; L232-W445 HydrophobicContact CD1-CZ2 4.41Å; L232-W445 HydrophobicContact CD1-CZ3 3.79Å; L232-W445 HydrophobicContact CD2-CH2 3.31Å; L232-W445 HydrophobicContact CD2-CZ2 3.62Å; L232-W445 HydrophobicContact CD2-CZ3 4.48Å; L232-W445 HydrophobicContact CG-CH2 3.85Å
233	R	92.9	Very high	93.4	Very high	20 Å²	20	15.3 Å²	15.3	8%	0.075	8%	0.079	C	C	.	.	H	α-helix	trans	-75.2	-30.4	178.2	-67.5	-61.1	-166.2	-160.5	-2.4	114.2	D55 F170 Y229 G230 M231 S236 F237	D55-R233 IonicContact OD1-CZ 3.64Å; D55-R233 IonicContact OD1-NH2 3.88Å; D55-R233 PolarHBondContact OD1-NH2 3.46Å; D55-R233 IonicContact OD2-CZ 3.48Å; D55-R233 IonicContact OD2-NH1 3.06Å; D55-R233 PolarHBondContact OD2-NH1 3.35Å; D55-R233 IonicContact OD2-NH2 2.84Å; D55-R233 PolarHBondContact OD2-NH2 2.98Å; F170-R233 HydrophobicContact CD1-CB 3.99Å; F170-R233 HydrophobicContact CE1-CB 3.6Å; F170-R233 HydrophobicContact CE1-CG 4.33Å; F170-R233 HydrophobicContact CZ-CB 3.97Å; F170-R233 HydrophobicContact CZ-CG 4.31Å; Y229-R233 HydrophobicContact CE1-CG 4.08Å; Y229-R233 HydrophobicContact CE2-CG 4.17Å; Y229-R233 WeakPolarHBondContact O-CG 3.17Å; Y229-R233 PolarHBondContact O-N 3.41Å; Y229-R233 VanDerWaalsContact O-N 3.09Å; Y229-R233 PolarHBondContact OH-NE 2.88Å; Y229-R233 PolarHBondContact OH-NH2 3.22Å; G230-R233 PolarHBondContact O-N 3.12Å; M231-R233 VanDerWaalsContact C-N 3.28Å; M231-R233 PolarHBondContact O-N 3.4Å; R233-S236 PolarHBondContact O-OG 3.18Å; R233-F237 WeakPolarHBondContact O-CE1 3.36Å
234	V	93.4	Very high	93.3	Very high	0 Å²	0	20.7 Å²	20.7	0%	0	10%	0.102	C	C	.	.	H	α-helix	trans	-88	-35.6	-177.3	166.4	0	0	0	0	111.8	L109 L187 L188 F191 G230 M231 S236 F237 L238	L109-V234 HydrophobicContact CD1-CG2 4.14Å; L187-V234 HydrophobicContact CB-CG1 3.91Å; L187-V234 HydrophobicContact CD1-CG1 4.41Å; L188-V234 HydrophobicContact CD2-CG1 4.27Å; F191-V234 HydrophobicContact CE2-CB 3.97Å; F191-V234 HydrophobicContact CE2-CG1 4.4Å; F191-V234 HydrophobicContact CE2-CG2 3.59Å; F191-V234 HydrophobicContact CZ-CG2 3.99Å; G230-V234 WeakPolarHBondContact O-CB 3.39Å; G230-V234 WeakPolarHBondContact O-CG2 3.26Å; G230-V234 PolarHBondContact O-N 3.31Å; M231-V234 PolarHBondContact O-N 3.31Å; M231-V234 VanDerWaalsContact O-N 3.16Å; V234-S236 PolarHBondContact O-N 3.46Å; V234-F237 VanDerWaalsContact CA-CE1 3.5Å; V234-F237 HydrophobicContact CB-CE1 4.24Å; V234-F237 HydrophobicContact CB-CZ 4.01Å; V234-F237 HydrophobicContact CG1-CE1 4.47Å; V234-F237 HydrophobicContact CG1-CE2 4.19Å; V234-F237 HydrophobicContact CG1-CZ 3.79Å; V234-F237 HydrophobicContact CG2-CE1 4.13Å; V234-F237 HydrophobicContact CG2-CZ 3.9Å; V234-F237 PolarHBondContact O-N 3.27Å; V234-L238 HydrophobicContact CG1-CD1 3.42Å; V234-L238 VanDerWaalsContact CG1-CD1 3.42Å; V234-L238 HydrophobicContact CG1-CG 4.1Å; V234-L238 WeakPolarHBondContact O-CG 3.27Å; V234-L238 PolarHBondContact O-N 3.48Å
235	I	92.5	Very high	93.3	Very high	3 Å²	3	23.3 Å²	23.3	2%	0.015	11%	0.113	C	C	.	.	H	α-helix	trans	-61.3	-31.7	177.4	-77.1	172.9	0	0	0	111.7	L188 M231 F237 L238 Q239 L290 M292	L188-I235 HydrophobicContact CD2-CG1 4.15Å; M231-I235 HydrophobicContact CB-CD1 3.99Å; M231-I235 HydrophobicContact CE-CD1 4.44Å; M231-I235 WeakPolarHBondContact O-CB 3.46Å; M231-I235 WeakPolarHBondContact O-CD1 3.43Å; M231-I235 WeakPolarHBondContact O-CG1 3.42Å; M231-I235 PolarHBondContact O-N 3.18Å; I235-F237 PolarHBondContact O-N 2.98Å; I235-L238 CarbonylContact O-C 3.34Å; I235-L238 PolarHBondContact O-N 3.05Å; I235-L238 VanDerWaalsContact O-N 3.13Å; I235-Q239 WeakPolarHBondContact O-CG 3.19Å; I235-Q239 PolarHBondContact O-N 3.26Å; I235-L290 HydrophobicContact CD1-CD2 4.29Å; I235-M292 HydrophobicContact CB-SD 4.47Å; I235-M292 HydrophobicContact CG2-CE 3.36Å; I235-M292 HydrophobicContact CG2-SD 3.01Å; I235-M292 WeakPolarHBondContact CG2-SD 3.42Å
236	S	89.8	Confident	93.1	Very high	27 Å²	27	23.7 Å²	23.7	19%	0.189	12%	0.115	C	C	.	.	T	Hydrogen-bonded Turn	trans	-58.5	-32.5	-178.9	60.7	0	0	0	0	113.7	N174 R233 V234 Q239	N174-S236 WeakPolarHBondContact OD1-CB 2.85Å; N174-S236 PolarHBondContact OD1-OG 2.79Å; R233-S236 PolarHBondContact O-OG 3.18Å; V234-S236 PolarHBondContact O-N 3.46Å; S236-Q239 VanDerWaalsContact O-CG 3.31Å; S236-Q239 WeakPolarHBondContact O-CG 3.42Å; S236-Q239 PolarHBondContact O-NE2 3.16Å
237	F	90.9	Very high	93.1	Very high	0 Å²	0	29.3 Å²	29.3	0%	0	14%	0.14	C	C	.	.	T	Hydrogen-bonded Turn	trans	-104.3	-7.5	175.4	62.5	-101.4	0	0	0	113.8	L109 L161 M173 F178 L187 R233 V234 I235	L109-F237 HydrophobicContact CD1-CE1 3.63Å; L109-F237 HydrophobicContact CD1-CZ 3.49Å; L109-F237 VanDerWaalsContact CD1-CZ 3.49Å; L161-F237 HydrophobicContact CD1-CE2 4Å; L161-F237 HydrophobicContact CD1-CZ 4.26Å; M173-F237 HydrophobicContact CB-CD1 4.1Å; M173-F237 HydrophobicContact CB-CG 4.44Å; M173-F237 HydrophobicContact CE-CD2 4.43Å; M173-F237 HydrophobicContact CE-CE2 4.47Å; M173-F237 WeakPolarHBondContact O-CB 3.19Å; F178-F237 HydrophobicContact CD2-CB 4.48Å; F178-F237 AromaticContact CD2-CD2 3.91Å; F178-F237 HydrophobicContact CD2-CD2 3.91Å; F178-F237 HydrophobicContact CE2-CB 4.42Å; F178-F237 HydrophobicContact CE2-CD2 4.17Å; L187-F237 HydrophobicContact CD1-CE2 3.84Å; L187-F237 HydrophobicContact CD1-CZ 4.23Å; R233-F237 WeakPolarHBondContact O-CE1 3.36Å; V234-F237 VanDerWaalsContact CA-CE1 3.5Å; V234-F237 HydrophobicContact CB-CE1 4.24Å; V234-F237 HydrophobicContact CB-CZ 4.01Å; V234-F237 HydrophobicContact CG1-CE1 4.47Å; V234-F237 HydrophobicContact CG1-CE2 4.19Å; V234-F237 HydrophobicContact CG1-CZ 3.79Å; V234-F237 HydrophobicContact CG2-CE1 4.13Å; V234-F237 HydrophobicContact CG2-CZ 3.9Å; V234-F237 PolarHBondContact O-N 3.27Å; I235-F237 PolarHBondContact O-N 2.98Å
238	L	91.6	Very high	93.1	Very high	0 Å²	0	31.7 Å²	31.7	0%	0	15%	0.154	C	C	.	.			trans	-102.8	23.2	175.6	-63	-175.6	0	0	0	113.8	F178 L183 Y184 L187 L188 V234 I235 L240 M241 N242	F178-L238 HydrophobicContact CB-CD2 4.26Å; L183-L238 HydrophobicContact CD2-CD2 3.45Å; L183-L238 VanDerWaalsContact CD2-CD2 3.45Å; Y184-L238 HydrophobicContact CD2-CD1 4.35Å; L187-L238 HydrophobicContact CB-CD1 4.11Å; L187-L238 HydrophobicContact CD1-CD1 4.03Å; L187-L238 HydrophobicContact CD1-CD2 4.4Å; L188-L238 HydrophobicContact CG-CD1 4.34Å; V234-L238 HydrophobicContact CG1-CD1 3.42Å; V234-L238 VanDerWaalsContact CG1-CD1 3.42Å; V234-L238 HydrophobicContact CG1-CG 4.1Å; V234-L238 WeakPolarHBondContact O-CG 3.27Å; V234-L238 PolarHBondContact O-N 3.48Å; I235-L238 CarbonylContact O-C 3.34Å; I235-L238 PolarHBondContact O-N 3.05Å; I235-L238 VanDerWaalsContact O-N 3.13Å; L238-L240 PolarHBondContact O-N 3.21Å; L238-M241 PolarHBondContact O-N 2.68Å; L238-N242 WeakPolarHBondContact O-CB 3.46Å; L238-N242 PolarHBondContact O-N 3.03Å
239	Q	92	Very high	93.2	Very high	73 Å²	73	33.4 Å²	33.4	34%	0.341	16%	0.161	S	C	.	.	H	α-helix	trans	-55.9	-47.8	-171.2	-56.8	-174.9	5.8	0	0	113	M177 I235 S236 M241 N242 L243 M292	M177-Q239 HydrophobicContact CE-CB 4.33Å; M177-Q239 HydrophobicContact CE-CG 4.49Å; M177-Q239 HydrophobicContact SD-CB 4.13Å; M177-Q239 HydrophobicContact SD-CG 4.47Å; I235-Q239 WeakPolarHBondContact O-CG 3.19Å; I235-Q239 PolarHBondContact O-N 3.26Å; S236-Q239 VanDerWaalsContact O-CG 3.31Å; S236-Q239 WeakPolarHBondContact O-CG 3.42Å; S236-Q239 PolarHBondContact O-NE2 3.16Å; Q239-M241 VanDerWaalsContact C-N 3.35Å; Q239-M241 PolarHBondContact O-N 3.03Å; Q239-N242 PolarHBondContact O-N 3.44Å; Q239-L243 WeakPolarHBondContact O-CG 3.42Å; Q239-L243 PolarHBondContact O-N 2.92Å; Q239-M292 HydrophobicContact CG-CE 4.01Å
240	L	91.5	Very high	93.2	Very high	67 Å²	67	33.4 Å²	33.4	35%	0.351	16%	0.161	S	C	.	.	H	α-helix	trans	-60.7	-42.3	-177.5	-68.1	177.1	0	0	0	112.7	M177 N179 L238 K244	M177-L240 HydrophobicContact CB-CD1 3.78Å; M177-L240 HydrophobicContact CB-CG 4.45Å; M177-L240 HydrophobicContact CG-CD1 4.38Å; M177-L240 HydrophobicContact SD-CD1 4.48Å; M177-L240 HydrophobicContact SD-CG 4.18Å; N179-L240 WeakPolarHBondContact OD1-CB 3.3Å; N179-L240 WeakPolarHBondContact OD1-CD1 3.4Å; L238-L240 PolarHBondContact O-N 3.21Å; L240-K244 PolarHBondContact O-N 3.16Å
241	M	92.5	Very high	93.2	Very high	0 Å²	0	36.2 Å²	36.2	0%	0	18%	0.18	C	C	.	.	H	α-helix	trans	-75.5	-35.7	-179.7	-55.8	-54.8	-75.1	0	0	111.3	F178 N179 D181 Y184 L238 Q239 L243 K244 Y245	F178-M241 VanDerWaalsContact O-CG 3.28Å; F178-M241 WeakPolarHBondContact O-CG 3.43Å; N179-M241 VanDerWaalsContact CA-SD 3.57Å; D181-M241 HydrophobicContact CB-CE 4Å; D181-M241 WeakPolarHBondContact OD1-CE 3.37Å; Y184-M241 HydrophobicContact CD2-CB 3.43Å; Y184-M241 VanDerWaalsContact CD2-CB 3.43Å; Y184-M241 HydrophobicContact CE2-CB 4.15Å; Y184-M241 HydrophobicContact CG-CB 3.86Å; L238-M241 PolarHBondContact O-N 2.68Å; Q239-M241 VanDerWaalsContact C-N 3.35Å; Q239-M241 PolarHBondContact O-N 3.03Å; M241-L243 VanDerWaalsContact C-N 3.33Å; M241-L243 PolarHBondContact O-N 3.47Å; M241-K244 WeakPolarHBondContact O-CB 3.44Å; M241-K244 PolarHBondContact O-N 2.98Å; M241-K244 VanDerWaalsContact O-N 3.17Å; M241-K244 HydrophobicContact SD-CD 4.32Å; M241-Y245 HydrophobicContact CE-CE2 4.14Å; M241-Y245 WeakPolarHBondContact O-CD2 3.42Å; M241-Y245 PolarHBondContact O-N 2.62Å; M241-Y245 VanDerWaalsContact O-N 3.09Å
242	N	92.8	Very high	93.3	Very high	0 Å²	0	38 Å²	38	0%	0	19%	0.19	C	C	.	.	H	α-helix	trans	-63.3	-40.9	175.8	-164.6	43.6	0	0	0	111.9	Y184 L238 Q239 K244 Y245 S246 L290 M292	Y184-N242 VanDerWaalsContact CE2-CA 3.45Å; Y184-N242 HydrophobicContact CE2-CB 3.94Å; Y184-N242 PolarHBondContact OH-OD1 3.37Å; L238-N242 WeakPolarHBondContact O-CB 3.46Å; L238-N242 PolarHBondContact O-N 3.03Å; Q239-N242 PolarHBondContact O-N 3.44Å; N242-K244 VanDerWaalsContact C-N 3.26Å; N242-K244 PolarHBondContact O-N 3.41Å; N242-Y245 PolarHBondContact O-N 3.35Å; N242-S246 WeakPolarHBondContact O-CA 3.45Å; N242-S246 WeakPolarHBondContact O-CB 3.24Å; N242-S246 PolarHBondContact O-N 3.44Å; N242-S246 PolarHBondContact O-OG 3.4Å; N242-L290 WeakPolarHBondContact OD1-CD2 3.27Å; N242-M292 WeakPolarHBondContact ND2-CG 3.35Å; N242-M292 PolarHBondContact ND2-SD 3.07Å; N242-M292 VanDerWaalsContact ND2-SD 3.38Å
243	L	91.7	Very high	93.4	Very high	108 Å²	108	37.4 Å²	37.4	57%	0.565	19%	0.187	S	C	*	.	H	α-helix	trans	-57.5	-40.5	174.2	-70	171.9	0	0	0	111.8	Q239 M241 S246	Q239-L243 WeakPolarHBondContact O-CG 3.42Å; Q239-L243 PolarHBondContact O-N 2.92Å; M241-L243 VanDerWaalsContact C-N 3.33Å; M241-L243 PolarHBondContact O-N 3.47Å; L243-S246 PolarHBondContact O-OG 3.29Å
244	K	93.8	Very high	93.5	Very high	116 Å²	116	36.6 Å²	36.6	50%	0.504	18%	0.184	S	C	.	.	H	α-helix	trans	-65.9	-44.2	177.8	-67.8	178.6	-178.5	177	0	113.5	L240 M241 N242 F247	L240-K244 PolarHBondContact O-N 3.16Å; M241-K244 WeakPolarHBondContact O-CB 3.44Å; M241-K244 PolarHBondContact O-N 2.98Å; M241-K244 VanDerWaalsContact O-N 3.17Å; M241-K244 HydrophobicContact SD-CD 4.32Å; N242-K244 VanDerWaalsContact C-N 3.26Å; N242-K244 PolarHBondContact O-N 3.41Å; K244-F247 VanDerWaalsContact O-CD1 3.23Å; K244-F247 WeakPolarHBondContact O-CD1 3.37Å; K244-F247 WeakPolarHBondContact O-CE1 3.35Å
245	Y	94.1	Very high	93.6	Very high	56 Å²	56	39.8 Å²	39.8	22%	0.22	20%	0.203	C	C	.	.	H	α-helix	trans	-100.5	-7.6	-172.1	-67.6	-67.7	0	0	0	115	D181 Y184 F185 M241 N242 F247 V248	D181-Y245 VanDerWaalsContact OD1-CE2 3.27Å; D181-Y245 WeakPolarHBondContact OD1-CE2 3.39Å; D181-Y245 PolarHBondContact OD1-OH 3.43Å; Y184-Y245 AromaticContact CD1-CD2 3.53Å; Y184-Y245 HydrophobicContact CD1-CD2 3.53Å; Y184-Y245 HydrophobicContact CD1-CE2 4.11Å; Y184-Y245 HydrophobicContact CD1-CG 4.18Å; Y184-Y245 AromaticContact CE1-CD2 3.51Å; Y184-Y245 HydrophobicContact CE1-CD2 3.51Å; Y184-Y245 HydrophobicContact CE1-CE2 4.48Å; Y184-Y245 AromaticContact CE1-CG 3.73Å; Y184-Y245 HydrophobicContact CE1-CG 3.73Å; Y184-Y245 HydrophobicContact CG-CD2 4.12Å; F185-Y245 HydrophobicContact CE2-CE1 4.12Å; F185-Y245 HydrophobicContact CE2-CE2 4.18Å; F185-Y245 AromaticContact CE2-CZ 3.88Å; F185-Y245 AromaticContact CZ-CD1 3.99Å; F185-Y245 HydrophobicContact CZ-CD1 3.99Å; F185-Y245 AromaticContact CZ-CE1 3.81Å; F185-Y245 HydrophobicContact CZ-CE1 3.81Å; F185-Y245 HydrophobicContact CZ-CE2 4.38Å; F185-Y245 HydrophobicContact CZ-CG 4.36Å; M241-Y245 HydrophobicContact CE-CE2 4.14Å; M241-Y245 WeakPolarHBondContact O-CD2 3.42Å; M241-Y245 PolarHBondContact O-N 2.62Å; M241-Y245 VanDerWaalsContact O-N 3.09Å; N242-Y245 PolarHBondContact O-N 3.35Å; Y245-F247 PolarHBondContact O-N 3.07Å; Y245-F247 VanDerWaalsContact O-N 3.11Å; Y245-V248 PolarHBondContact O-N 3.11Å; Y245-V248 VanDerWaalsContact O-N 3.11Å
246	S	93	Very high	93.8	Very high	8 Å²	8	39.7 Å²	39.7	6%	0.056	20%	0.203	C	C	.	.	H	α-helix	trans	-49.1	-41.6	-176.8	55.7	0	0	0	0	113.3	N242 L243 V248 W249 I250	N242-S246 WeakPolarHBondContact O-CA 3.45Å; N242-S246 WeakPolarHBondContact O-CB 3.24Å; N242-S246 PolarHBondContact O-N 3.44Å; N242-S246 PolarHBondContact O-OG 3.4Å; L243-S246 PolarHBondContact O-OG 3.29Å; S246-V248 VanDerWaalsContact C-N 3.29Å; S246-V248 PolarHBondContact O-N 3.11Å; S246-W249 PolarHBondContact O-N 3.38Å; S246-I250 WeakPolarHBondContact O-CB 3.21Å; S246-I250 VanDerWaalsContact O-CG1 3.24Å; S246-I250 WeakPolarHBondContact O-CG1 3.27Å; S246-I250 PolarHBondContact O-N 2.94Å
247	F	93.8	Very high	94.1	Very high	117 Å²	117	38.6 Å²	38.6	51%	0.513	20%	0.196	S	C	.	.	H	α-helix	trans	-58.1	-38.3	-176.9	74.7	-90.5	0	0	0	113.2	K244 Y245 S251 W376	K244-F247 VanDerWaalsContact O-CD1 3.23Å; K244-F247 WeakPolarHBondContact O-CD1 3.37Å; K244-F247 WeakPolarHBondContact O-CE1 3.35Å; Y245-F247 PolarHBondContact O-N 3.07Å; Y245-F247 VanDerWaalsContact O-N 3.11Å; F247-S251 WeakPolarHBondContact O-CB 3.25Å; F247-S251 PolarHBondContact O-N 3.43Å; F247-S251 VanDerWaalsContact O-N 3.11Å; F247-S251 PolarHBondContact O-OG 3.49Å; F247-W376 HydrophobicContact CB-CH2 4.07Å; F247-W376 HydrophobicContact CB-CZ2 3.75Å
248	V	95.5	Very high	94.4	Very high	50 Å²	50	39.4 Å²	39.4	30%	0.303	20%	0.201	S	C	.	.	H	α-helix	trans	-64	-52.9	-179	178.8	0	0	0	0	109.2	Y245 S246 S251 I252	Y245-V248 PolarHBondContact O-N 3.11Å; Y245-V248 VanDerWaalsContact O-N 3.11Å; S246-V248 VanDerWaalsContact C-N 3.29Å; S246-V248 PolarHBondContact O-N 3.11Å; V248-S251 PolarHBondContact O-N 2.85Å; V248-S251 PolarHBondContact O-OG 3.44Å; V248-I252 HydrophobicContact CG1-CD1 3.88Å; V248-I252 WeakPolarHBondContact O-CG1 3.42Å; V248-I252 PolarHBondContact O-N 2.97Å; V248-I252 VanDerWaalsContact O-N 3.14Å
249	W	95	Very high	94.6	Very high	37 Å²	37	43.1 Å²	43.1	14%	0.14	22%	0.22	C	C	.	.	H	α-helix	trans	-70.9	-38.5	-174.1	-59.1	127.6	0	0	0	113.1	Y184 F185 L192 M197 S246 S251 I252 S253 L290	Y184-W249 AromaticContact CE1-NE1 3.73Å; Y184-W249 AromaticContact CZ-NE1 3.9Å; Y184-W249 VanDerWaalsContact OH-CD1 3.32Å; Y184-W249 PolarHBondContact OH-NE1 2.92Å; F185-W249 HydrophobicContact CD1-CZ2 4.17Å; F185-W249 AromaticContact CE1-CZ2 3.95Å; F185-W249 HydrophobicContact CE1-CZ2 3.95Å; L192-W249 HydrophobicContact CD1-CD2 3.92Å; L192-W249 HydrophobicContact CD1-CE3 3.95Å; L192-W249 HydrophobicContact CD1-CH2 3.59Å; L192-W249 HydrophobicContact CD1-CZ2 3.61Å; L192-W249 HydrophobicContact CD1-CZ3 3.77Å; M197-W249 HydrophobicContact CE-CB 3.88Å; M197-W249 HydrophobicContact CE-CD2 3.77Å; M197-W249 HydrophobicContact CE-CE3 3.14Å; M197-W249 HydrophobicContact CE-CG 4.11Å; M197-W249 HydrophobicContact CE-CZ3 3.84Å; M197-W249 HydrophobicContact SD-CE3 3.45Å; M197-W249 HydrophobicContact SD-CZ3 3.6Å; S246-W249 PolarHBondContact O-N 3.38Å; W249-S251 VanDerWaalsContact C-N 3.32Å; W249-S251 PolarHBondContact O-N 3.48Å; W249-I252 HydrophobicContact CE3-CD1 4.07Å; W249-I252 HydrophobicContact CZ3-CD1 4.39Å; W249-I252 PolarHBondContact O-N 3.19Å; W249-S253 WeakPolarHBondContact O-CB 3.37Å; W249-S253 PolarHBondContact O-N 3.46Å; W249-S253 PolarHBondContact O-OG 2.87Å; W249-L290 HydrophobicContact CB-CD1 3.35Å; W249-L290 HydrophobicContact CG-CD1 4.24Å
250	I	95.7	Very high	94.9	Very high	0 Å²	0	39.7 Å²	39.7	0%	0	20%	0.204	C	C	.	.	H	α-helix	trans	-61.4	-42.7	174.4	-66.7	166.5	0	0	0	110.2	S246 S253 L254 L290 T291 W376	S246-I250 WeakPolarHBondContact O-CB 3.21Å; S246-I250 VanDerWaalsContact O-CG1 3.24Å; S246-I250 WeakPolarHBondContact O-CG1 3.27Å; S246-I250 PolarHBondContact O-N 2.94Å; I250-S253 PolarHBondContact O-N 3.3Å; I250-S253 PolarHBondContact O-OG 3.33Å; I250-S253 VanDerWaalsContact O-OG 3.1Å; I250-L254 HydrophobicContact CG2-CD1 3.78Å; I250-L254 HydrophobicContact CG2-CG 4.29Å; I250-L254 WeakPolarHBondContact O-CB 3.33Å; I250-L254 WeakPolarHBondContact O-CG 3.1Å; I250-L254 PolarHBondContact O-N 3.33Å; I250-L290 HydrophobicContact CD1-CB 4.22Å; I250-L290 HydrophobicContact CG1-CB 3.89Å; I250-T291 HydrophobicContact CD1-CG2 4.18Å; I250-W376 HydrophobicContact CB-CZ3 4.48Å; I250-W376 HydrophobicContact CD1-CD2 3.98Å; I250-W376 HydrophobicContact CD1-CE3 4.32Å; I250-W376 HydrophobicContact CD1-CG 4.43Å; I250-W376 HydrophobicContact CD1-CH2 4.47Å; I250-W376 HydrophobicContact CD1-CZ2 4.11Å; I250-W376 HydrophobicContact CG2-CE3 4.06Å; I250-W376 HydrophobicContact CG2-CH2 4.32Å; I250-W376 HydrophobicContact CG2-CZ3 3.82Å
251	S	95.5	Very high	95.1	Very high	58 Å²	58	36.6 Å²	36.6	41%	0.406	19%	0.188	S	C	.	.	H	α-helix	trans	-64.1	-43.9	179.4	72.6	0	0	0	0	112.2	F247 V248 W249 S253 V255	F247-S251 WeakPolarHBondContact O-CB 3.25Å; F247-S251 PolarHBondContact O-N 3.43Å; F247-S251 VanDerWaalsContact O-N 3.11Å; F247-S251 PolarHBondContact O-OG 3.49Å; V248-S251 PolarHBondContact O-N 2.85Å; V248-S251 PolarHBondContact O-OG 3.44Å; W249-S251 VanDerWaalsContact C-N 3.32Å; W249-S251 PolarHBondContact O-N 3.48Å; S251-S253 VanDerWaalsContact C-N 3.34Å; S251-S253 PolarHBondContact O-N 3.33Å; S251-V255 WeakPolarHBondContact O-CB 3.47Å; S251-V255 VanDerWaalsContact O-CG2 3.31Å; S251-V255 WeakPolarHBondContact O-CG2 3.38Å; S251-V255 PolarHBondContact O-N 3.43Å; S251-V255 VanDerWaalsContact O-N 3.11Å
252	I	96.7	Very high	95.3	Very high	42 Å²	42	39.8 Å²	39.8	22%	0.215	21%	0.205	C	C	.	.	H	α-helix	trans	-64.4	-40.1	178	-65.1	165.3	0	0	0	110.8	M197 F198 V248 W249 G256	M197-I252 HydrophobicContact CG-CG2 3.78Å; M197-I252 HydrophobicContact SD-CB 4.38Å; M197-I252 HydrophobicContact SD-CG2 3.81Å; F198-I252 HydrophobicContact CB-CG2 4.21Å; V248-I252 HydrophobicContact CG1-CD1 3.88Å; V248-I252 WeakPolarHBondContact O-CG1 3.42Å; V248-I252 PolarHBondContact O-N 2.97Å; V248-I252 VanDerWaalsContact O-N 3.14Å; W249-I252 HydrophobicContact CE3-CD1 4.07Å; W249-I252 HydrophobicContact CZ3-CD1 4.39Å; W249-I252 PolarHBondContact O-N 3.19Å; I252-G256 WeakPolarHBondContact O-CA 3.38Å; I252-G256 PolarHBondContact O-N 3.11Å
253	S	95.9	Very high	95.5	Very high	4 Å²	4	41.7 Å²	41.7	3%	0.028	22%	0.216	C	C	.	.	H	α-helix	trans	-72.2	-42.1	-177.2	76.7	0	0	0	0	112.9	W249 I250 S251 G257 G283 S287	W249-S253 WeakPolarHBondContact O-CB 3.37Å; W249-S253 PolarHBondContact O-N 3.46Å; W249-S253 PolarHBondContact O-OG 2.87Å; I250-S253 PolarHBondContact O-N 3.3Å; I250-S253 PolarHBondContact O-OG 3.33Å; I250-S253 VanDerWaalsContact O-OG 3.1Å; S251-S253 VanDerWaalsContact C-N 3.34Å; S251-S253 PolarHBondContact O-N 3.33Å; S253-G257 PolarHBondContact O-N 3.14Å; S253-G283 PolarHBondContact OG-O 3.03Å; S253-S287 WeakPolarHBondContact OG-CB 3.01Å
254	L	95.8	Very high	95.7	Very high	3 Å²	3	36.5 Å²	36.5	2%	0.016	19%	0.189	C	C	.	.	H	α-helix	trans	-68.9	-50.8	179	-69.3	176.3	0	0	0	111.6	I250 G256 G257 V258 I373 L383 L384 L387	I250-L254 HydrophobicContact CG2-CD1 3.78Å; I250-L254 HydrophobicContact CG2-CG 4.29Å; I250-L254 WeakPolarHBondContact O-CB 3.33Å; I250-L254 WeakPolarHBondContact O-CG 3.1Å; I250-L254 PolarHBondContact O-N 3.33Å; L254-G256 VanDerWaalsContact C-N 3.32Å; L254-G256 PolarHBondContact O-N 3.11Å; L254-G257 PolarHBondContact O-N 2.9Å; L254-V258 WeakPolarHBondContact O-CG2 3.15Å; L254-V258 PolarHBondContact O-N 3.3Å; L254-I373 HydrophobicContact CD1-CG2 3.99Å; L254-I373 HydrophobicContact CD2-CD1 4.48Å; L254-I373 HydrophobicContact CD2-CG2 4.45Å; L254-L383 HydrophobicContact CB-CB 4.21Å; L254-L383 HydrophobicContact CB-CD1 3.77Å; L254-L383 HydrophobicContact CD1-CD1 4.39Å; L254-L384 HydrophobicContact CD2-CD2 3.72Å; L254-L384 HydrophobicContact CD2-CG 4.47Å; L254-L387 HydrophobicContact CD2-CD1 3.81Å
255	V	96.6	Very high	95.8	Very high	67 Å²	67	33.6 Å²	33.6	41%	0.406	18%	0.179	S	C	.	.	H	α-helix	trans	-62.5	-44.6	177.7	175.1	0	0	0	0	110.1	S251 G257 V258 L259 L383	S251-V255 WeakPolarHBondContact O-CB 3.47Å; S251-V255 VanDerWaalsContact O-CG2 3.31Å; S251-V255 WeakPolarHBondContact O-CG2 3.38Å; S251-V255 PolarHBondContact O-N 3.43Å; S251-V255 VanDerWaalsContact O-N 3.11Å; V255-G257 PolarHBondContact O-N 2.76Å; V255-V258 PolarHBondContact O-N 3.08Å; V255-L259 HydrophobicContact CG1-CD1 4.15Å; V255-L259 WeakPolarHBondContact O-CG 3.48Å; V255-L259 PolarHBondContact O-N 3.17Å; V255-L383 HydrophobicContact CG2-CD1 3.95Å; V255-L383 HydrophobicContact CG2-CD2 4.38Å
256	G	95.9	Very high	95.9	Very high	1 Å²	1	40.1 Å²	40.1	1%	0.01	20%	0.203	C	C	.	.	H	α-helix	trans	-62	-41	178.3	0	0	0	0	0	113.9	F198 I252 L254 V258 L259 V260	F198-G256 VanDerWaalsContact CB-CA 3.49Å; F198-G256 VanDerWaalsContact CD2-CA 3.42Å; F198-G256 WeakPolarHBondContact CD2-O 3.38Å; I252-G256 WeakPolarHBondContact O-CA 3.38Å; I252-G256 PolarHBondContact O-N 3.11Å; L254-G256 VanDerWaalsContact C-N 3.32Å; L254-G256 PolarHBondContact O-N 3.11Å; G256-V258 VanDerWaalsContact C-N 3.33Å; G256-V258 PolarHBondContact O-N 3.46Å; G256-L259 PolarHBondContact O-N 3.21Å; G256-V260 WeakPolarHBondContact O-CB 3.3Å; G256-V260 VanDerWaalsContact O-CG2 3.28Å; G256-V260 WeakPolarHBondContact O-CG2 3.44Å; G256-V260 PolarHBondContact O-N 3.23Å
257	G	95.7	Very high	96	Very high	3 Å²	3	41.7 Å²	41.7	3%	0.031	21%	0.209	C	C	.	.	H	α-helix	trans	-61.1	-41	175.4	0	0	0	0	0	112.1	S253 L254 V255 V260 S261	S253-G257 PolarHBondContact O-N 3.14Å; L254-G257 PolarHBondContact O-N 2.9Å; V255-G257 PolarHBondContact O-N 2.76Å; G257-V260 PolarHBondContact O-N 3.06Å; G257-S261 WeakPolarHBondContact O-CB 3.35Å; G257-S261 PolarHBondContact O-N 2.97Å; G257-S261 PolarHBondContact O-OG 3.36Å
258	V	96.8	Very high	96.1	Very high	18 Å²	18	39.6 Å²	39.6	11%	0.109	21%	0.206	C	C	.	.	H	α-helix	trans	-63.2	-47.7	176.2	176.5	0	0	0	0	109.8	L254 V255 G256 V260 S261 L262 L383 F386 L387 F390	L254-V258 WeakPolarHBondContact O-CG2 3.15Å; L254-V258 PolarHBondContact O-N 3.3Å; V255-V258 PolarHBondContact O-N 3.08Å; G256-V258 VanDerWaalsContact C-N 3.33Å; G256-V258 PolarHBondContact O-N 3.46Å; V258-V260 VanDerWaalsContact C-N 3.34Å; V258-V260 PolarHBondContact O-N 3.38Å; V258-S261 PolarHBondContact O-N 3.32Å; V258-S261 PolarHBondContact O-OG 3.06Å; V258-L262 PolarHBondContact O-N 3.14Å; V258-L262 VanDerWaalsContact O-N 3.08Å; V258-L383 HydrophobicContact CG2-CD2 4.32Å; V258-F386 HydrophobicContact CG1-CB 4.25Å; V258-F386 HydrophobicContact CG2-CB 4.11Å; V258-L387 HydrophobicContact CG2-CD1 4.43Å; V258-L387 HydrophobicContact CG2-CD2 3.9Å; V258-L387 HydrophobicContact CG2-CG 3.66Å; V258-L387 VanDerWaalsContact N-CD2 3.28Å; V258-F390 HydrophobicContact CG1-CD2 4.36Å; V258-F390 HydrophobicContact CG1-CE2 4.24Å
259	L	96.9	Very high	96.1	Very high	78 Å²	78	39.7 Å²	39.7	41%	0.408	21%	0.205	S	C	.	.	H	α-helix	trans	-61.2	-42.1	179	-67.5	174.4	0	0	0	112.3	F198 V255 G256 L262 V263	F198-L259 HydrophobicContact CE1-CD1 3.81Å; F198-L259 HydrophobicContact CE2-CB 3.97Å; F198-L259 HydrophobicContact CE2-CD1 4.29Å; F198-L259 HydrophobicContact CZ-CB 3.99Å; F198-L259 HydrophobicContact CZ-CD1 3.49Å; F198-L259 VanDerWaalsContact CZ-CD1 3.49Å; F198-L259 HydrophobicContact CZ-CG 4.4Å; V255-L259 HydrophobicContact CG1-CD1 4.15Å; V255-L259 WeakPolarHBondContact O-CG 3.48Å; V255-L259 PolarHBondContact O-N 3.17Å; G256-L259 PolarHBondContact O-N 3.21Å; L259-L262 PolarHBondContact O-N 3.34Å; L259-V263 WeakPolarHBondContact O-CG2 3.48Å; L259-V263 PolarHBondContact O-N 3.18Å
260	V	97.1	Very high	96.1	Very high	1 Å²	1	38.1 Å²	38.1	1%	0.006	20%	0.199	C	C	.	.	H	α-helix	trans	-64.9	-40.4	176.3	172.2	0	0	0	0	111.2	F198 G256 G257 V258 L262 V263 C264 Y276 V279	F198-V260 HydrophobicContact CD2-CG2 3.75Å; F198-V260 HydrophobicContact CE2-CG2 3.99Å; G256-V260 WeakPolarHBondContact O-CB 3.3Å; G256-V260 VanDerWaalsContact O-CG2 3.28Å; G256-V260 WeakPolarHBondContact O-CG2 3.44Å; G256-V260 PolarHBondContact O-N 3.23Å; G257-V260 PolarHBondContact O-N 3.06Å; V258-V260 VanDerWaalsContact C-N 3.34Å; V258-V260 PolarHBondContact O-N 3.38Å; V260-L262 VanDerWaalsContact C-N 3.29Å; V260-L262 PolarHBondContact O-N 3.41Å; V260-V263 CarbonylContact O-C 3.53Å; V260-V263 WeakPolarHBondContact O-CA 3.41Å; V260-V263 WeakPolarHBondContact O-CB 3.25Å; V260-V263 PolarHBondContact O-N 3.3Å; V260-C264 PolarHBondContact O-N 3.42Å; V260-C264 PolarHBondContact O-SG 3.14Å; V260-Y276 HydrophobicContact CG1-CD1 3.94Å; V260-Y276 HydrophobicContact CG1-CG 4.4Å; V260-Y276 WeakPolarHBondContact CG1-O 3.4Å; V260-V279 HydrophobicContact CG1-CB 4.12Å; V260-V279 HydrophobicContact CG1-CG1 4.2Å; V260-V279 HydrophobicContact CG2-CG1 4.03Å
261	S	96.6	Very high	96.1	Very high	1 Å²	1	38.3 Å²	38.3	1%	0.007	20%	0.2	C	C	.	.	H	α-helix	trans	-62	-35.6	176.9	75	0	0	0	0	112.7	G257 V258 C264 F390	G257-S261 WeakPolarHBondContact O-CB 3.35Å; G257-S261 PolarHBondContact O-N 2.97Å; G257-S261 PolarHBondContact O-OG 3.36Å; V258-S261 PolarHBondContact O-N 3.32Å; V258-S261 PolarHBondContact O-OG 3.06Å; S261-C264 WeakPolarHBondContact O-CB 3.43Å; S261-C264 PolarHBondContact O-N 2.89Å; S261-F390 WeakPolarHBondContact OG-CB 3.41Å; S261-F390 WeakPolarHBondContact OG-CD2 3.5Å
262	L	96.6	Very high	96.1	Very high	67 Å²	67	35.9 Å²	35.9	35%	0.351	18%	0.184	S	C	.	.	H	α-helix	trans	-68.8	-34.9	171.3	-68.7	172.6	0	0	0	112.4	V258 L259 V260 F390	V258-L262 PolarHBondContact O-N 3.14Å; V258-L262 VanDerWaalsContact O-N 3.08Å; L259-L262 PolarHBondContact O-N 3.34Å; V260-L262 VanDerWaalsContact C-N 3.29Å; V260-L262 PolarHBondContact O-N 3.41Å; L262-F390 HydrophobicContact CD2-CD1 4.18Å; L262-F390 HydrophobicContact CD2-CD2 4.38Å; L262-F390 HydrophobicContact CD2-CE1 3.67Å; L262-F390 HydrophobicContact CD2-CE2 3.91Å; L262-F390 HydrophobicContact CD2-CZ 3.54Å; L262-F390 HydrophobicContact CG-CE2 4.34Å; L262-F390 HydrophobicContact CG-CZ 4.44Å
263	V	97	Very high	96.2	Very high	40 Å²	40	34 Å²	34	24%	0.242	17%	0.174	C	C	.	.	H	α-helix	trans	-63.4	-42.8	172.7	171.5	0	0	0	0	110.2	L259 V260 L265 R266 Q267 Y276	L259-V263 WeakPolarHBondContact O-CG2 3.48Å; L259-V263 PolarHBondContact O-N 3.18Å; V260-V263 CarbonylContact O-C 3.53Å; V260-V263 WeakPolarHBondContact O-CA 3.41Å; V260-V263 WeakPolarHBondContact O-CB 3.25Å; V260-V263 PolarHBondContact O-N 3.3Å; V263-L265 VanDerWaalsContact C-N 3.27Å; V263-L265 PolarHBondContact O-N 3.44Å; V263-R266 PolarHBondContact O-N 3.45Å; V263-Q267 HydrophobicContact CG1-CG 4.33Å; V263-Q267 VanDerWaalsContact CG1-NE2 3.25Å; V263-Q267 WeakPolarHBondContact O-CG 3.24Å; V263-Q267 PolarHBondContact O-N 3.04Å; V263-Y276 HydrophobicContact CG1-CD1 4.41Å; V263-Y276 HydrophobicContact CG1-CD2 4.42Å; V263-Y276 HydrophobicContact CG1-CE1 4.3Å; V263-Y276 HydrophobicContact CG1-CE2 4.34Å; V263-Y276 HydrophobicContact CG1-CG 4.47Å
264	C	96.2	Very high	96.2	Very high	0 Å²	0	33.8 Å²	33.8	0%	0	17%	0.173	C	C	.	.	H	α-helix	trans	-53	-42.2	178.3	-65.1	0	0	0	0	113	V260 S261 R266 Q267 L273 Y276 Y394	V260-C264 PolarHBondContact O-N 3.42Å; V260-C264 PolarHBondContact O-SG 3.14Å; S261-C264 WeakPolarHBondContact O-CB 3.43Å; S261-C264 PolarHBondContact O-N 2.89Å; C264-R266 PolarHBondContact O-N 3.39Å; C264-Q267 PolarHBondContact O-N 3Å; C264-Q267 VanDerWaalsContact O-N 3.13Å; C264-L273 HydrophobicContact CB-CG 4.48Å; C264-Y276 WeakPolarHBondContact SG-CB 3.39Å; C264-Y394 HydrophobicContact CB-CD1 3.92Å; C264-Y394 HydrophobicContact CB-CG 3.88Å
265	L	95.7	Very high	96.3	Very high	54 Å²	54	33.6 Å²	33.6	28%	0.283	17%	0.172	S	C	.	.	H	α-helix	trans	-63.6	-21.9	-179.7	-69.5	172.2	0	0	0	113.7	V263 F390 A393	V263-L265 VanDerWaalsContact C-N 3.27Å; V263-L265 PolarHBondContact O-N 3.44Å; L265-F390 HydrophobicContact CD1-CD1 4Å; L265-F390 HydrophobicContact CD1-CE1 4.38Å; L265-A393 HydrophobicContact CD2-CB 4.09Å
266	R	96	Very high	96.3	Very high	193 Å²	193	32.3 Å²	32.3	73%	0.728	16%	0.16	S	C	*	.	H	α-helix	trans	-98.6	-6.4	178.4	-63.5	-171.3	-66.3	173.4	-0	113.3	V263 C264 T268	V263-R266 PolarHBondContact O-N 3.45Å; C264-R266 PolarHBondContact O-N 3.39Å; R266-T268 PolarHBondContact O-N 3.11Å
267	Q	95.4	Very high	96.3	Very high	41 Å²	41	32.3 Å²	32.3	19%	0.192	16%	0.16	C	C	.	.			trans	-73.1	130.1	-177.9	-68.8	-60.2	-18.7	0	0	111.1	V263 C264 L273 Y276	V263-Q267 HydrophobicContact CG1-CG 4.33Å; V263-Q267 VanDerWaalsContact CG1-NE2 3.25Å; V263-Q267 WeakPolarHBondContact O-CG 3.24Å; V263-Q267 PolarHBondContact O-N 3.04Å; C264-Q267 PolarHBondContact O-N 3Å; C264-Q267 VanDerWaalsContact O-N 3.13Å; Q267-L273 HydrophobicContact CB-CB 4.04Å; Q267-L273 HydrophobicContact CB-CG 4.45Å; Q267-Y276 HydrophobicContact CG-CD2 3.84Å; Q267-Y276 HydrophobicContact CG-CE2 4.12Å
268	T	95.5	Very high	96.3	Very high	74 Å²	74	32.2 Å²	32.2	45%	0.454	16%	0.159	S	C	.	.			trans	-92.3	-17.9	175.6	52.9	0	0	0	0	112.8	R266 M330	R266-T268 PolarHBondContact O-N 3.11Å; T268-M330 VanDerWaalsContact O-CB 3.25Å; T268-M330 WeakPolarHBondContact O-CB 3.45Å; T268-M330 WeakPolarHBondContact O-CG 3.48Å; T268-M330 PolarHBondContact O-N 3.47Å
269	D	95.8	Very high	96.3	Very high	52 Å²	52	31.5 Å²	31.5	28%	0.278	16%	0.155	S	C	.	.	B	Isolated β-bridge	trans	-94.7	126.9	-179	-74.6	-28	0	0	0	111.6	K271 A272 L273	D269-K271 PolarHBondContact O-N 2.86Å; D269-A272 HydrophobicContact CB-CB 3.76Å; D269-A272 PolarHBondContact O-N 3.28Å; D269-L273 WeakPolarHBondContact O-CB 3.46Å; D269-L273 PolarHBondContact O-N 3.28Å
270	L	95.1	Very high	96.2	Very high	3 Å²	3	28 Å²	28	2%	0.016	14%	0.137	C	C	.	.	H	α-helix	trans	-56.5	-50.8	-179.3	-84.9	161.2	0	0	0	112.6	L273 I274 R328 M330 N333 W347	L270-L273 PolarHBondContact O-N 2.98Å; L270-I274 WeakPolarHBondContact O-CG1 3.37Å; L270-I274 PolarHBondContact O-N 3.11Å; L270-I274 VanDerWaalsContact O-N 3.14Å; L270-R328 WeakPolarHBondContact CB-O 3.47Å; L270-R328 PolarHBondContact N-O 3.13Å; L270-M330 HydrophobicContact CB-SD 4.46Å; L270-M330 HydrophobicContact CD1-SD 4.33Å; L270-M330 HydrophobicContact CD2-CE 4.43Å; L270-M330 HydrophobicContact CD2-CG 4.41Å; L270-M330 HydrophobicContact CD2-SD 3.08Å; L270-M330 WeakPolarHBondContact CD2-SD 3.13Å; L270-M330 HydrophobicContact CG-CG 4.12Å; L270-M330 HydrophobicContact CG-SD 3.35Å; L270-M330 WeakPolarHBondContact CG-SD 3.37Å; L270-N333 HydrophobicContact CD1-CB 3.87Å; L270-N333 WeakPolarHBondContact CD1-ND2 3.16Å; L270-W347 HydrophobicContact CD2-CH2 4.18Å
271	K	96.1	Very high	96.2	Very high	4 Å²	4	28 Å²	28	2%	0.017	14%	0.137	C	C	.	.	H	α-helix	trans	-66.4	-39.3	-178.9	-74.9	-166.5	179.3	-174.7	0	112	V209 A211 D269 I274 A275 F315 A318	V209-K271 HydrophobicContact CG2-CB 4.08Å; A211-K271 PolarHBondContact O-NZ 3.33Å; D269-K271 PolarHBondContact O-N 2.86Å; K271-I274 PolarHBondContact O-N 3.35Å; K271-A275 WeakPolarHBondContact O-CB 3.39Å; K271-A275 PolarHBondContact O-N 2.99Å; K271-F315 HydrophobicContact CB-CE1 4.44Å; K271-A318 HydrophobicContact CG-CB 4.36Å
272	A	95.7	Very high	96.1	Very high	8 Å²	8	28 Å²	28	7%	0.066	14%	0.137	C	C	.	.	H	α-helix	trans	-66	-42.5	179.4	0	0	0	0	0	110.5	V209 D269 I274 A275 Y276	V209-A272 HydrophobicContact CG2-CB 3.78Å; D269-A272 HydrophobicContact CB-CB 3.76Å; D269-A272 PolarHBondContact O-N 3.28Å; A272-I274 PolarHBondContact O-N 2.91Å; A272-A275 WeakPolarHBondContact O-CB 3.37Å; A272-A275 PolarHBondContact O-N 3.33Å; A272-A275 VanDerWaalsContact O-N 3.15Å; A272-Y276 HydrophobicContact CB-CE2 4.47Å; A272-Y276 WeakPolarHBondContact O-CD2 3.29Å; A272-Y276 PolarHBondContact O-N 3.37Å
273	L	97	Very high	96.1	Very high	1 Å²	1	25.3 Å²	25.3	1%	0.005	12%	0.124	C	C	.	.	H	α-helix	trans	-59.1	-46.6	175.9	-169.6	163.1	0	0	0	111.5	C264 Q267 D269 L270 A275 Y276 S277 Y394 Y397 L398	C264-L273 HydrophobicContact CB-CG 4.48Å; Q267-L273 HydrophobicContact CB-CB 4.04Å; Q267-L273 HydrophobicContact CB-CG 4.45Å; D269-L273 WeakPolarHBondContact O-CB 3.46Å; D269-L273 PolarHBondContact O-N 3.28Å; L270-L273 PolarHBondContact O-N 2.98Å; L273-A275 VanDerWaalsContact C-N 3.3Å; L273-A275 PolarHBondContact O-N 3.46Å; L273-Y276 PolarHBondContact O-N 2.68Å; L273-S277 PolarHBondContact O-N 3.33Å; L273-Y394 HydrophobicContact CD2-CD2 4.4Å; L273-Y397 HydrophobicContact CD1-CD1 3.7Å; L273-Y397 HydrophobicContact CD1-CE1 3.73Å; L273-L398 HydrophobicContact CD1-CB 4.43Å; L273-L398 HydrophobicContact CD2-CB 4.2Å; L273-L398 HydrophobicContact CD2-CD1 3.88Å
274	I	97.4	Very high	96	Very high	0 Å²	0	24.2 Å²	24.2	0%	0	12%	0.117	C	C	.	.	H	α-helix	trans	-61.6	-40.2	176.1	-61	162.2	0	0	0	110.7	L270 K271 A272 S277 S278 L314 F315 A318 L398	L270-I274 WeakPolarHBondContact O-CG1 3.37Å; L270-I274 PolarHBondContact O-N 3.11Å; L270-I274 VanDerWaalsContact O-N 3.14Å; K271-I274 PolarHBondContact O-N 3.35Å; A272-I274 PolarHBondContact O-N 2.91Å; I274-S277 PolarHBondContact O-N 3.38Å; I274-S277 PolarHBondContact O-OG 3.34Å; I274-S278 PolarHBondContact O-N 3.31Å; I274-S278 VanDerWaalsContact O-N 3.11Å; I274-L314 HydrophobicContact CD1-CB 4.07Å; I274-L314 HydrophobicContact CG1-CB 4.33Å; I274-L314 HydrophobicContact CG2-CB 4Å; I274-F315 HydrophobicContact CB-CD1 4.5Å; I274-F315 HydrophobicContact CB-CE1 4.02Å; I274-F315 HydrophobicContact CB-CE2 4.5Å; I274-F315 HydrophobicContact CB-CZ 4.01Å; I274-F315 HydrophobicContact CG2-CD1 4.2Å; I274-F315 HydrophobicContact CG2-CD2 3.91Å; I274-F315 HydrophobicContact CG2-CE1 3.9Å; I274-F315 HydrophobicContact CG2-CE2 3.57Å; I274-F315 HydrophobicContact CG2-CG 4.2Å; I274-F315 HydrophobicContact CG2-CZ 3.57Å; I274-A318 HydrophobicContact CD1-CB 3.81Å; I274-L398 HydrophobicContact CG1-CD1 3.91Å
275	A	96.7	Very high	96.1	Very high	0 Å²	0	24.2 Å²	24.2	0%	0	12%	0.117	C	C	.	.	H	α-helix	trans	-65	-40.1	177	0	0	0	0	0	113.4	L204 H208 K271 A272 L273 S278 V279 F315	L204-A275 HydrophobicContact CD2-CB 3.74Å; L204-A275 WeakPolarHBondContact CD2-O 3.45Å; H208-A275 HydrophobicContact CB-CB 3.86Å; K271-A275 WeakPolarHBondContact O-CB 3.39Å; K271-A275 PolarHBondContact O-N 2.99Å; A272-A275 WeakPolarHBondContact O-CB 3.37Å; A272-A275 PolarHBondContact O-N 3.33Å; A272-A275 VanDerWaalsContact O-N 3.15Å; L273-A275 VanDerWaalsContact C-N 3.3Å; L273-A275 PolarHBondContact O-N 3.46Å; A275-S278 PolarHBondContact O-N 3.46Å; A275-S278 PolarHBondContact O-OG 3.47Å; A275-V279 PolarHBondContact O-N 3.02Å; A275-F315 HydrophobicContact CB-CZ 4.25Å
276	Y	96.8	Very high	96.1	Very high	39 Å²	39	21.8 Å²	21.8	15%	0.153	10%	0.104	C	C	.	.	H	α-helix	trans	-70.5	-33.6	173.8	-75.2	-69.6	0	0	0	112	P205 V260 V263 C264 Q267 A272 L273 S278 V279 A280	P205-Y276 HydrophobicContact CB-CE1 4.31Å; P205-Y276 HydrophobicContact CB-CE2 3.98Å; P205-Y276 HydrophobicContact CG-CD1 3.94Å; P205-Y276 HydrophobicContact CG-CD2 4.45Å; P205-Y276 HydrophobicContact CG-CE1 3.46Å; P205-Y276 VanDerWaalsContact CG-CE1 3.46Å; P205-Y276 HydrophobicContact CG-CE2 4Å; P205-Y276 HydrophobicContact CG-CG 4.41Å; P205-Y276 VanDerWaalsContact CG-CZ 3.48Å; V260-Y276 HydrophobicContact CG1-CD1 3.94Å; V260-Y276 HydrophobicContact CG1-CG 4.4Å; V260-Y276 WeakPolarHBondContact CG1-O 3.4Å; V263-Y276 HydrophobicContact CG1-CD1 4.41Å; V263-Y276 HydrophobicContact CG1-CD2 4.42Å; V263-Y276 HydrophobicContact CG1-CE1 4.3Å; V263-Y276 HydrophobicContact CG1-CE2 4.34Å; V263-Y276 HydrophobicContact CG1-CG 4.47Å; C264-Y276 WeakPolarHBondContact SG-CB 3.39Å; Q267-Y276 HydrophobicContact CG-CD2 3.84Å; Q267-Y276 HydrophobicContact CG-CE2 4.12Å; A272-Y276 HydrophobicContact CB-CE2 4.47Å; A272-Y276 WeakPolarHBondContact O-CD2 3.29Å; A272-Y276 PolarHBondContact O-N 3.37Å; L273-Y276 PolarHBondContact O-N 2.68Å; Y276-S278 VanDerWaalsContact C-N 3.28Å; Y276-S278 PolarHBondContact O-N 2.96Å; Y276-V279 WeakPolarHBondContact O-CB 3.24Å; Y276-V279 PolarHBondContact O-N 3.13Å; Y276-A280 PolarHBondContact O-N 3.21Å; Y276-A280 VanDerWaalsContact O-N 3.13Å
277	S	95.9	Very high	96.1	Very high	2 Å²	2	12.6 Å²	12.6	1%	0.014	7%	0.07	C	C	.	.	H	α-helix	trans	-61.3	-36.9	173.7	77.4	0	0	0	0	112.3	L273 I274 V279 A280 H281 Y394	L273-S277 PolarHBondContact O-N 3.33Å; I274-S277 PolarHBondContact O-N 3.38Å; I274-S277 PolarHBondContact O-OG 3.34Å; S277-V279 VanDerWaalsContact C-N 3.34Å; S277-V279 PolarHBondContact O-N 3.39Å; S277-A280 PolarHBondContact O-N 3.14Å; S277-H281 PolarHBondContact O-CD2 3.14Å; S277-H281 PolarHBondContact O-N 3.44Å; S277-H281 VanDerWaalsContact O-N 3.08Å; S277-Y394 VanDerWaalsContact CB-CE2 3.46Å
278	S	95.7	Very high	96.1	Very high	0 Å²	0	10.6 Å²	10.6	0%	0	6%	0.061	C	C	.	.	H	α-helix	trans	-68.5	-32.8	177	66.3	0	0	0	0	112.9	I274 A275 Y276 A280 M282 H307	I274-S278 PolarHBondContact O-N 3.31Å; I274-S278 VanDerWaalsContact O-N 3.11Å; A275-S278 PolarHBondContact O-N 3.46Å; A275-S278 PolarHBondContact O-OG 3.47Å; Y276-S278 VanDerWaalsContact C-N 3.28Å; Y276-S278 PolarHBondContact O-N 2.96Å; S278-A280 VanDerWaalsContact C-N 3.34Å; S278-M282 VanDerWaalsContact O-CB 3.27Å; S278-M282 WeakPolarHBondContact O-CB 3.37Å; S278-M282 WeakPolarHBondContact O-CG 3.47Å; S278-M282 PolarHBondContact O-N 3.27Å; S278-H307 WeakPolarHBondContact CA-NE2 3.4Å; S278-H307 WeakPolarHBondContact CB-NE2 3.37Å
279	V	96.5	Very high	96.1	Very high	4 Å²	4	7.2 Å²	7.2	2%	0.024	4%	0.039	C	C	.	.	H	α-helix	trans	-63	-41.2	171.1	177.6	0	0	0	0	110.8	P196 H201 L204 V260 A275 Y276 S277 G283	P196-V279 HydrophobicContact CB-CG2 4.25Å; P196-V279 HydrophobicContact CG-CG2 4.02Å; H201-V279 HydrophobicContact CB-CG1 3.89Å; H201-V279 HydrophobicContact CB-CG2 4.11Å; L204-V279 HydrophobicContact CD1-CG2 3.87Å; L204-V279 HydrophobicContact CD2-CG2 4.09Å; L204-V279 HydrophobicContact CG-CG2 4.46Å; V260-V279 HydrophobicContact CG1-CB 4.12Å; V260-V279 HydrophobicContact CG1-CG1 4.2Å; V260-V279 HydrophobicContact CG2-CG1 4.03Å; A275-V279 PolarHBondContact O-N 3.02Å; Y276-V279 WeakPolarHBondContact O-CB 3.24Å; Y276-V279 PolarHBondContact O-N 3.13Å; S277-V279 VanDerWaalsContact C-N 3.34Å; S277-V279 PolarHBondContact O-N 3.39Å; V279-G283 PolarHBondContact O-N 3.46Å
280	A	96.3	Very high	96.1	Very high	4 Å²	4	4.8 Å²	4.8	3%	0.033	3%	0.026	C	C	.	.	H	α-helix	trans	-64.3	-50.8	178.5	0	0	0	0	0	112.3	Y276 S277 S278 M282 G283 I284	Y276-A280 PolarHBondContact O-N 3.21Å; Y276-A280 VanDerWaalsContact O-N 3.13Å; S277-A280 PolarHBondContact O-N 3.14Å; S278-A280 VanDerWaalsContact C-N 3.34Å; A280-M282 PolarHBondContact O-N 3.35Å; A280-G283 PolarHBondContact O-N 3Å; A280-G283 VanDerWaalsContact O-N 3.15Å; A280-I284 PolarHBondContact O-N 3.48Å
281	H	95.7	Very high	96	Very high	1 Å²	1	5.2 Å²	5.2	1%	0.005	3%	0.029	C	C	.	.	H	α-helix	trans	-63	-42	178	-69.6	-76.5	0	0	0	111.9	S277 G283 I284 V285 L303 H307 N354 E366 Y394	S277-H281 PolarHBondContact O-CD2 3.14Å; S277-H281 PolarHBondContact O-N 3.44Å; S277-H281 VanDerWaalsContact O-N 3.08Å; H281-G283 VanDerWaalsContact C-N 3.27Å; H281-G283 PolarHBondContact O-N 3.32Å; H281-I284 PolarHBondContact O-N 3.47Å; H281-V285 WeakPolarHBondContact O-CG2 3.44Å; H281-V285 PolarHBondContact O-N 3.4Å; H281-V285 VanDerWaalsContact O-N 3.16Å; H281-L303 HydrophobicContact CB-CD2 4.31Å; H281-H307 AromaticContact CD2-CE1 3.62Å; H281-H307 AromaticContact CD2-ND1 3.72Å; H281-H307 AromaticContact CG-CE1 3.96Å; H281-H307 AromaticContact CG-ND1 3.75Å; H281-N354 PolarHBondContact CE1-O 2.83Å; H281-N354 VanDerWaalsContact CE1-O 3.31Å; H281-N354 PolarHBondContact NE2-OD1 3.01Å; H281-N354 VanDerWaalsContact NE2-OD1 3.16Å; H281-E366 IonicContact CE1-OE1 2.79Å; H281-E366 PolarHBondContact CE1-OE1 3.01Å; H281-E366 IonicContact ND1-OE1 2.66Å; H281-E366 PolarHBondContact ND1-OE1 2.94Å; H281-Y394 PolarHBondContact NE2-OH 2.98Å
282	M	95.5	Very high	95.8	Very high	2 Å²	2	7.1 Å²	7.1	1%	0.01	4%	0.039	C	C	.	.	H	α-helix	trans	-67.1	-27.1	175.9	-68.2	-64.6	158.6	0	0	113	M195 L224 K225 S278 A280 I284 V285 L286 H307	M195-M282 HydrophobicContact CE-CB 4.35Å; M195-M282 HydrophobicContact CE-SD 3.69Å; M195-M282 HydrophobicContact SD-SD 3.86Å; L224-M282 HydrophobicContact CD1-CG 4.37Å; K225-M282 HydrophobicContact CD-CE 3.91Å; K225-M282 VanDerWaalsContact NZ-CE 3.26Å; S278-M282 VanDerWaalsContact O-CB 3.27Å; S278-M282 WeakPolarHBondContact O-CB 3.37Å; S278-M282 WeakPolarHBondContact O-CG 3.47Å; S278-M282 PolarHBondContact O-N 3.27Å; A280-M282 PolarHBondContact O-N 3.35Å; M282-I284 VanDerWaalsContact C-N 3.34Å; M282-V285 WeakPolarHBondContact O-CB 3.44Å; M282-V285 PolarHBondContact O-N 3.42Å; M282-V285 HydrophobicContact SD-CG2 4.28Å; M282-L286 WeakPolarHBondContact O-CB 3.45Å; M282-L286 PolarHBondContact O-N 3.12Å; M282-H307 HydrophobicContact CE-CB 4.18Å; M282-H307 WeakPolarHBondContact CE-CD2 3.47Å
283	G	95.6	Very high	95.7	Very high	9 Å²	9	8.6 Å²	8.6	9%	0.093	5%	0.047	C	C	.	.	H	α-helix	trans	-61.3	-40.6	171.1	0	0	0	0	0	112.7	S253 V279 A280 H281 L286 S287	S253-G283 PolarHBondContact OG-O 3.03Å; V279-G283 PolarHBondContact O-N 3.46Å; A280-G283 PolarHBondContact O-N 3Å; A280-G283 VanDerWaalsContact O-N 3.15Å; H281-G283 VanDerWaalsContact C-N 3.27Å; H281-G283 PolarHBondContact O-N 3.32Å; G283-L286 PolarHBondContact O-N 3.11Å; G283-S287 PolarHBondContact O-N 3.34Å; G283-S287 PolarHBondContact O-OG 3.44Å; G283-S287 VanDerWaalsContact O-OG 3.12Å
284	I	96.1	Very high	95.5	Very high	17 Å²	17	12.8 Å²	12.8	9%	0.087	6%	0.063	C	C	.	.	H	α-helix	trans	-66.9	-43.9	175	-56.9	171.3	0	0	0	110.4	A280 H281 M282 L286 S287 G288 L369 I373 L387	A280-I284 PolarHBondContact O-N 3.48Å; H281-I284 PolarHBondContact O-N 3.47Å; M282-I284 VanDerWaalsContact C-N 3.34Å; I284-L286 VanDerWaalsContact C-N 3.3Å; I284-L286 PolarHBondContact O-N 3.38Å; I284-S287 WeakPolarHBondContact CA-OG 3.36Å; I284-S287 PolarHBondContact O-N 3.14Å; I284-S287 PolarHBondContact O-OG 3.38Å; I284-G288 PolarHBondContact O-N 2.98Å; I284-L369 HydrophobicContact CG2-CB 3.99Å; I284-L369 HydrophobicContact CG2-CD1 3.96Å; I284-I373 HydrophobicContact CG2-CD1 4.24Å; I284-L387 HydrophobicContact CD1-CB 4.47Å; I284-L387 HydrophobicContact CG1-CD1 4.21Å
285	V	96.8	Very high	95.4	Very high	0 Å²	0	19 Å²	19	0%	0	9%	0.087	C	C	.	.	H	α-helix	trans	-56.3	-46.7	174.2	-179.9	0	0	0	0	110.6	M195 H281 M282 G288 L289 L303 M304 L369	M195-V285 HydrophobicContact CE-CB 4.03Å; M195-V285 HydrophobicContact CE-CG1 3.65Å; H281-V285 WeakPolarHBondContact O-CG2 3.44Å; H281-V285 PolarHBondContact O-N 3.4Å; H281-V285 VanDerWaalsContact O-N 3.16Å; M282-V285 WeakPolarHBondContact O-CB 3.44Å; M282-V285 PolarHBondContact O-N 3.42Å; M282-V285 HydrophobicContact SD-CG2 4.28Å; V285-G288 PolarHBondContact O-N 3.05Å; V285-L289 HydrophobicContact CG1-CD1 3.83Å; V285-L289 HydrophobicContact CG1-CG 4.21Å; V285-L289 WeakPolarHBondContact O-CB 3.36Å; V285-L289 VanDerWaalsContact O-CG 3.29Å; V285-L289 WeakPolarHBondContact O-CG 3.44Å; V285-L289 PolarHBondContact O-N 3.48Å; V285-L303 HydrophobicContact CG2-CB 4.03Å; V285-L303 HydrophobicContact CG2-CD2 3.17Å; V285-L303 HydrophobicContact CG2-CG 4.16Å; V285-M304 HydrophobicContact CG1-CG 4.04Å; V285-L369 HydrophobicContact CG2-CD1 4.36Å
286	L	96.6	Very high	95.3	Very high	3 Å²	3	19 Å²	19	2%	0.016	9%	0.087	C	C	.	.	H	α-helix	trans	-63	-43.8	-178.9	-170.7	142.9	0	0	0	111.7	L192 M195 M197 M282 G283 I284 L290	L192-L286 HydrophobicContact CD2-CD1 3.72Å; L192-L286 HydrophobicContact CD2-CG 4.43Å; M195-L286 HydrophobicContact CB-CD1 4.2Å; M197-L286 HydrophobicContact CE-CD1 4.31Å; M197-L286 HydrophobicContact CE-CD2 3.77Å; M282-L286 WeakPolarHBondContact O-CB 3.45Å; M282-L286 PolarHBondContact O-N 3.12Å; G283-L286 PolarHBondContact O-N 3.11Å; I284-L286 VanDerWaalsContact C-N 3.3Å; I284-L286 PolarHBondContact O-N 3.38Å; L286-L290 HydrophobicContact CD2-CD1 3.53Å; L286-L290 HydrophobicContact CG-CD1 4.13Å; L286-L290 WeakPolarHBondContact O-CD1 3.38Å; L286-L290 VanDerWaalsContact O-CG 3.24Å; L286-L290 WeakPolarHBondContact O-CG 3.42Å; L286-L290 PolarHBondContact O-N 3.1Å
287	S	96	Very high	95.2	Very high	0 Å²	0	18 Å²	18	0%	0	8%	0.084	C	C	.	.	H	α-helix	trans	-60.8	-45.4	173.5	36.6	0	0	0	0	112.2	S253 G283 I284 L290 T291 I373	S253-S287 WeakPolarHBondContact OG-CB 3.01Å; G283-S287 PolarHBondContact O-N 3.34Å; G283-S287 PolarHBondContact O-OG 3.44Å; G283-S287 VanDerWaalsContact O-OG 3.12Å; I284-S287 WeakPolarHBondContact CA-OG 3.36Å; I284-S287 PolarHBondContact O-N 3.14Å; I284-S287 PolarHBondContact O-OG 3.38Å; S287-L290 PolarHBondContact O-N 3.1Å; S287-T291 WeakPolarHBondContact O-CG2 3.36Å; S287-T291 PolarHBondContact O-N 3.47Å; S287-I373 VanDerWaalsContact OG-CD1 3.26Å; S287-I373 WeakPolarHBondContact OG-CD1 3.39Å
288	G	95.9	Very high	95.1	Very high	0 Å²	0	17.9 Å²	17.9	0%	0	8%	0.083	C	C	.	.	H	α-helix	trans	-66.2	-41.7	-178.5	0	0	0	0	0	113.1	I284 V285 L290 T291	I284-G288 PolarHBondContact O-N 2.98Å; V285-G288 PolarHBondContact O-N 3.05Å; G288-L290 VanDerWaalsContact C-N 3.28Å; G288-L290 PolarHBondContact O-N 3.01Å; G288-T291 PolarHBondContact O-N 3.34Å; G288-T291 PolarHBondContact O-OG1 2.97Å
289	L	95.4	Very high	95.1	Very high	2 Å²	2	17.9 Å²	17.9	1%	0.01	8%	0.083	C	C	.	.	H	α-helix	trans	-54.8	-44.8	174	-80.2	171.7	0	0	0	111.9	M195 L232 V285 T291 M292 L297 S300	M195-L289 HydrophobicContact CE-CD1 4.43Å; L232-L289 HydrophobicContact CD1-CD2 4.21Å; L232-L289 HydrophobicContact CD2-CD2 3.24Å; L232-L289 HydrophobicContact CG-CD2 3.61Å; V285-L289 HydrophobicContact CG1-CD1 3.83Å; V285-L289 HydrophobicContact CG1-CG 4.21Å; V285-L289 WeakPolarHBondContact O-CB 3.36Å; V285-L289 VanDerWaalsContact O-CG 3.29Å; V285-L289 WeakPolarHBondContact O-CG 3.44Å; V285-L289 PolarHBondContact O-N 3.48Å; L289-T291 VanDerWaalsContact C-N 3.31Å; L289-T291 PolarHBondContact O-N 2.9Å; L289-M292 PolarHBondContact O-N 2.98Å; L289-L297 HydrophobicContact CD2-CD2 4.15Å; L289-S300 VanDerWaalsContact CD2-CB 3.5Å; L289-S300 WeakPolarHBondContact CD2-OG 3.47Å
290	L	95.4	Very high	95.1	Very high	1 Å²	1	17.7 Å²	17.7	1%	0.005	8%	0.082	C	C	.	.	H	α-helix	trans	-77.6	-14	-173.9	-66.8	169.4	0	0	0	113.8	M231 I235 N242 W249 I250 L286 S287 G288 M292	M231-L290 HydrophobicContact CE-CD2 3.98Å; I235-L290 HydrophobicContact CD1-CD2 4.29Å; N242-L290 WeakPolarHBondContact OD1-CD2 3.27Å; W249-L290 HydrophobicContact CB-CD1 3.35Å; W249-L290 HydrophobicContact CG-CD1 4.24Å; I250-L290 HydrophobicContact CD1-CB 4.22Å; I250-L290 HydrophobicContact CG1-CB 3.89Å; L286-L290 HydrophobicContact CD2-CD1 3.53Å; L286-L290 HydrophobicContact CG-CD1 4.13Å; L286-L290 WeakPolarHBondContact O-CD1 3.38Å; L286-L290 VanDerWaalsContact O-CG 3.24Å; L286-L290 WeakPolarHBondContact O-CG 3.42Å; L286-L290 PolarHBondContact O-N 3.1Å; S287-L290 PolarHBondContact O-N 3.1Å; G288-L290 VanDerWaalsContact C-N 3.28Å; G288-L290 PolarHBondContact O-N 3.01Å; L290-M292 PolarHBondContact O-N 3.31Å
291	T	94	Very high	95	Very high	13 Å²	13	17.6 Å²	17.6	8%	0.08	8%	0.081	C	C	.	.	T	Hydrogen-bonded Turn	trans	-68.4	-17.7	172.5	66	0	0	0	0	113.8	I250 S287 G288 L289 T293 I373 W376	I250-T291 HydrophobicContact CD1-CG2 4.18Å; S287-T291 WeakPolarHBondContact O-CG2 3.36Å; S287-T291 PolarHBondContact O-N 3.47Å; G288-T291 PolarHBondContact O-N 3.34Å; G288-T291 PolarHBondContact O-OG1 2.97Å; L289-T291 VanDerWaalsContact C-N 3.31Å; L289-T291 PolarHBondContact O-N 2.9Å; T291-T293 PolarHBondContact O-N 3.35Å; T291-T293 PolarHBondContact OG1-OG1 3.5Å; T291-T293 VanDerWaalsContact OG1-OG1 3.11Å; T291-I373 HydrophobicContact CG2-CG1 4.31Å; T291-W376 HydrophobicContact CG2-CB 3.88Å; T291-W376 HydrophobicContact CG2-CG 4.2Å
292	M	92	Very high	95	Very high	44 Å²	44	17.6 Å²	17.6	22%	0.217	8%	0.081	C	C	.	.			trans	59.5	10.7	-177.4	-62.8	-57.8	-67.5	0	0	116.2	I235 Q239 N242 L289 L290	I235-M292 HydrophobicContact CB-SD 4.47Å; I235-M292 HydrophobicContact CG2-CE 3.36Å; I235-M292 HydrophobicContact CG2-SD 3.01Å; I235-M292 WeakPolarHBondContact CG2-SD 3.42Å; Q239-M292 HydrophobicContact CG-CE 4.01Å; N242-M292 WeakPolarHBondContact ND2-CG 3.35Å; N242-M292 PolarHBondContact ND2-SD 3.07Å; N242-M292 VanDerWaalsContact ND2-SD 3.38Å; L289-M292 PolarHBondContact O-N 2.98Å; L290-M292 PolarHBondContact O-N 3.31Å
293	T	93.1	Very high	95.1	Very high	38 Å²	38	17.5 Å²	17.5	23%	0.233	8%	0.081	C	C	.	.			trans	-79	149.8	175.2	61.4	0	0	0	0	110.5	T291 W295 G296 L297 S372	T291-T293 PolarHBondContact O-N 3.35Å; T291-T293 PolarHBondContact OG1-OG1 3.5Å; T291-T293 VanDerWaalsContact OG1-OG1 3.11Å; T293-W295 VanDerWaalsContact C-N 3.3Å; T293-W295 PolarHBondContact O-N 2.92Å; T293-G296 PolarHBondContact O-N 3.35Å; T293-G296 VanDerWaalsContact O-N 3.11Å; T293-G296 PolarHBondContact OG1-N 3.02Å; T293-G296 VanDerWaalsContact OG1-N 3.11Å; T293-L297 WeakPolarHBondContact O-CG 3.2Å; T293-L297 PolarHBondContact O-N 2.72Å; T293-S372 WeakPolarHBondContact OG1-CB 3.4Å
294	Y	93.2	Very high	95.1	Very high	89 Å²	89	17 Å²	17	35%	0.349	8%	0.076	S	C	.	.	H	α-helix	trans	-53.7	-47.9	174.8	-179.8	-98.9	0	0	0	111.7	G296 L297 C298 M443 L444 L446	Y294-G296 VanDerWaalsContact C-N 3.33Å; Y294-G296 PolarHBondContact O-N 3.14Å; Y294-L297 PolarHBondContact O-N 3.17Å; Y294-C298 PolarHBondContact O-N 3.03Å; Y294-C298 PolarHBondContact O-SG 2.88Å; Y294-M443 PolarHBondContact OH-O 3.07Å; Y294-L444 WeakPolarHBondContact OH-CD2 3.33Å; Y294-L446 HydrophobicContact CD2-CB 4.22Å; Y294-L446 HydrophobicContact CD2-CD1 4.17Å; Y294-L446 HydrophobicContact CE2-CB 3.89Å
295	W	93.7	Very high	95.1	Very high	131 Å²	131	16.4 Å²	16.4	50%	0.496	7%	0.073	S	C	.	.	H	α-helix	trans	-59.5	-41	177.1	-62	88.7	0	0	0	112.4	T293 G299 Y368	T293-W295 VanDerWaalsContact C-N 3.3Å; T293-W295 PolarHBondContact O-N 2.92Å; W295-G299 PolarHBondContact O-N 2.97Å; W295-Y368 HydrophobicContact CB-CD1 4.31Å; W295-Y368 HydrophobicContact CD2-CD1 4.08Å; W295-Y368 HydrophobicContact CD2-CE1 4.05Å; W295-Y368 AromaticContact CE3-CD1 3.15Å; W295-Y368 HydrophobicContact CE3-CD1 3.15Å; W295-Y368 AromaticContact CE3-CE1 2.98Å; W295-Y368 HydrophobicContact CE3-CE1 2.98Å; W295-Y368 HydrophobicContact CE3-CG 4.04Å; W295-Y368 AromaticContact CE3-CZ 3.83Å; W295-Y368 HydrophobicContact CH2-CE1 4.12Å; W295-Y368 AromaticContact CZ3-CD1 3.72Å; W295-Y368 HydrophobicContact CZ3-CD1 3.72Å; W295-Y368 AromaticContact CZ3-CE1 3.02Å; W295-Y368 HydrophobicContact CZ3-CE1 3.02Å; W295-Y368 HydrophobicContact CZ3-CE2 4.33Å; W295-Y368 AromaticContact CZ3-CZ 3.43Å; W295-Y368 VanDerWaalsContact CZ3-CZ 3.43Å
296	G	94.8	Very high	95.1	Very high	0 Å²	0	16.4 Å²	16.4	0%	0	7%	0.073	C	C	.	.	H	α-helix	trans	-66.9	-41.8	178.3	0	0	0	0	0	112.8	T293 Y294 S300 S372	T293-G296 PolarHBondContact O-N 3.35Å; T293-G296 VanDerWaalsContact O-N 3.11Å; T293-G296 PolarHBondContact OG1-N 3.02Å; T293-G296 VanDerWaalsContact OG1-N 3.11Å; Y294-G296 VanDerWaalsContact C-N 3.33Å; Y294-G296 PolarHBondContact O-N 3.14Å; G296-S300 VanDerWaalsContact O-CB 3.27Å; G296-S300 WeakPolarHBondContact O-CB 3.15Å; G296-S300 PolarHBondContact O-N 3.37Å; G296-S300 PolarHBondContact O-OG 3.31Å; G296-S372 VanDerWaalsContact CA-CB 3.45Å; G296-S372 WeakPolarHBondContact CA-OG 3.4Å
297	L	94.5	Very high	95.1	Very high	18 Å²	18	16.3 Å²	16.3	9%	0.094	7%	0.072	C	C	.	.	H	α-helix	trans	-64.9	-50.5	177.1	-70.5	177.4	0	0	0	111	L232 L289 T293 Y294 G299 S300 Y301 W445 L446	L232-L297 HydrophobicContact CD2-CD2 3.64Å; L289-L297 HydrophobicContact CD2-CD2 4.15Å; T293-L297 WeakPolarHBondContact O-CG 3.2Å; T293-L297 PolarHBondContact O-N 2.72Å; Y294-L297 PolarHBondContact O-N 3.17Å; L297-G299 PolarHBondContact O-N 3.29Å; L297-S300 PolarHBondContact O-N 3.33Å; L297-S300 PolarHBondContact O-OG 2.87Å; L297-Y301 PolarHBondContact O-N 3.25Å; L297-W445 HydrophobicContact CB-CZ2 3.89Å; L297-W445 WeakPolarHBondContact O-CZ2 3.34Å; L297-L446 HydrophobicContact CB-CD1 3.81Å; L297-L446 HydrophobicContact CD1-CD1 3.59Å; L297-L446 HydrophobicContact CG-CD1 4.35Å
298	C	94.9	Very high	95.1	Very high	0 Å²	0	16.3 Å²	16.3	0%	0	7%	0.072	C	C	.	.	H	α-helix	trans	-66.8	-39.6	178.2	-53.1	0	0	0	0	112.6	Y294 S300 Y301 T302 M443 W445	Y294-C298 PolarHBondContact O-N 3.03Å; Y294-C298 PolarHBondContact O-SG 2.88Å; C298-S300 VanDerWaalsContact C-N 3.32Å; C298-S300 PolarHBondContact O-N 3.22Å; C298-Y301 PolarHBondContact O-N 3.07Å; C298-T302 WeakPolarHBondContact O-CG2 3.41Å; C298-T302 PolarHBondContact O-N 2.92Å; C298-T302 VanDerWaalsContact O-N 3.14Å; C298-T302 PolarHBondContact O-OG1 3.31Å; C298-T302 VanDerWaalsContact O-OG1 3.12Å; C298-M443 HydrophobicContact CB-CE 3.65Å; C298-M443 PolarHBondContact SG-O 2.72Å; C298-W445 PolarHBondContact SG-NE1 3.11Å; C298-W445 VanDerWaalsContact SG-NE1 3.38Å
299	G	95.4	Very high	95.1	Very high	0 Å²	0	16.5 Å²	16.5	0%	0	7%	0.073	C	C	.	.	H	α-helix	trans	-62.1	-37.8	175.2	0	0	0	0	0	113	W295 L297 Y301 T302 L303	W295-G299 PolarHBondContact O-N 2.97Å; L297-G299 PolarHBondContact O-N 3.29Å; G299-Y301 PolarHBondContact O-N 3.32Å; G299-T302 WeakPolarHBondContact CA-OG1 3.22Å; G299-T302 PolarHBondContact O-OG1 3.42Å; G299-L303 WeakPolarHBondContact O-CB 3.4Å; G299-L303 PolarHBondContact O-N 3.47Å
300	S	95.7	Very high	95.1	Very high	0 Å²	0	16.4 Å²	16.4	0%	0	7%	0.073	C	C	.	.	H	α-helix	trans	-64.7	-40.7	177.8	73.7	0	0	0	0	112.4	L289 G296 L297 C298 M304	L289-S300 VanDerWaalsContact CD2-CB 3.5Å; L289-S300 WeakPolarHBondContact CD2-OG 3.47Å; G296-S300 VanDerWaalsContact O-CB 3.27Å; G296-S300 WeakPolarHBondContact O-CB 3.15Å; G296-S300 PolarHBondContact O-N 3.37Å; G296-S300 PolarHBondContact O-OG 3.31Å; L297-S300 PolarHBondContact O-N 3.33Å; L297-S300 PolarHBondContact O-OG 2.87Å; C298-S300 VanDerWaalsContact C-N 3.32Å; C298-S300 PolarHBondContact O-N 3.22Å; S300-M304 WeakPolarHBondContact O-CB 3.31Å; S300-M304 VanDerWaalsContact O-CG 3.26Å; S300-M304 WeakPolarHBondContact O-CG 3.16Å; S300-M304 PolarHBondContact O-N 3.1Å
301	Y	95.3	Very high	95.2	Very high	1 Å²	1	16.4 Å²	16.4	0%	0.004	7%	0.073	C	C	.	.	H	α-helix	trans	-66.8	-48	179.8	-176.8	-129.1	0	0	0	112.7	M56 L57 G60 L61 L297 C298 G299 L303 M304 I305 F442 W445	M56-Y301 PolarHBondContact O-OH 3.46Å; L57-Y301 HydrophobicContact CD2-CD2 4.17Å; L57-Y301 HydrophobicContact CD2-CE2 4.06Å; L57-Y301 WeakPolarHBondContact O-CE2 3.31Å; L57-Y301 PolarHBondContact O-OH 3.37Å; G60-Y301 VanDerWaalsContact CA-OH 3.25Å; G60-Y301 WeakPolarHBondContact CA-OH 3.48Å; G60-Y301 PolarHBondContact N-OH 2.77Å; L61-Y301 HydrophobicContact CG-CE2 4.23Å; L297-Y301 PolarHBondContact O-N 3.25Å; C298-Y301 PolarHBondContact O-N 3.07Å; G299-Y301 PolarHBondContact O-N 3.32Å; Y301-L303 VanDerWaalsContact C-N 3.34Å; Y301-L303 PolarHBondContact O-N 2.87Å; Y301-M304 HydrophobicContact CD2-CE 4.23Å; Y301-M304 WeakPolarHBondContact O-CB 3.45Å; Y301-M304 PolarHBondContact O-N 3.24Å; Y301-I305 HydrophobicContact CD1-CD1 4.35Å; Y301-I305 HydrophobicContact CD2-CD1 4.25Å; Y301-I305 HydrophobicContact CE1-CD1 3.87Å; Y301-I305 HydrophobicContact CE2-CD1 3.78Å; Y301-I305 HydrophobicContact CE2-CG1 4.38Å; Y301-I305 PolarHBondContact O-N 3.37Å; Y301-I305 VanDerWaalsContact O-N 3.14Å; Y301-F442 HydrophobicContact CD1-CB 4.11Å; Y301-F442 HydrophobicContact CD1-CD1 4.31Å; Y301-F442 WeakPolarHBondContact CD1-O 3.39Å; Y301-F442 HydrophobicContact CE1-CB 4.16Å; Y301-F442 AromaticContact CE1-CD1 3.64Å; Y301-F442 HydrophobicContact CE1-CD1 3.64Å; Y301-F442 HydrophobicContact CE1-CG 4.4Å; Y301-W445 HydrophobicContact CD1-CD2 4.16Å; Y301-W445 AromaticContact CD1-CE3 3.44Å; Y301-W445 HydrophobicContact CD1-CE3 3.44Å; Y301-W445 VanDerWaalsContact CD1-CE3 3.44Å; Y301-W445 AromaticContact CD1-CZ3 3.88Å; Y301-W445 HydrophobicContact CD1-CZ3 3.88Å; Y301-W445 AromaticContact CD2-CE3 3.67Å; Y301-W445 HydrophobicContact CD2-CE3 3.67Å; Y301-W445 HydrophobicContact CD2-CH2 4.32Å; Y301-W445 AromaticContact CD2-CZ3 3.29Å; Y301-W445 HydrophobicContact CD2-CZ3 3.29Å; Y301-W445 AromaticContact CE1-CE3 3.93Å; Y301-W445 HydrophobicContact CE1-CE3 3.93Å; Y301-W445 HydrophobicContact CE2-CE3 4.12Å; Y301-W445 HydrophobicContact CE2-CZ3 4.04Å; Y301-W445 HydrophobicContact CG-CD2 4.22Å; Y301-W445 AromaticContact CG-CE3 3.28Å; Y301-W445 HydrophobicContact CG-CE3 3.28Å; Y301-W445 HydrophobicContact CG-CH2 4.07Å; Y301-W445 AromaticContact CG-CZ3 3.18Å; Y301-W445 HydrophobicContact CG-CZ3 3.18Å
302	T	95.9	Very high	95.3	Very high	1 Å²	1	15.8 Å²	15.8	1%	0.006	7%	0.069	C	C	.	.	H	α-helix	trans	-61	-45.4	179.4	54.6	0	0	0	0	110.5	C298 G299 M304 I305 A306 L364 G365 F442 M443	C298-T302 WeakPolarHBondContact O-CG2 3.41Å; C298-T302 PolarHBondContact O-N 2.92Å; C298-T302 VanDerWaalsContact O-N 3.14Å; C298-T302 PolarHBondContact O-OG1 3.31Å; C298-T302 VanDerWaalsContact O-OG1 3.12Å; G299-T302 WeakPolarHBondContact CA-OG1 3.22Å; G299-T302 PolarHBondContact O-OG1 3.42Å; T302-M304 PolarHBondContact O-N 3.21Å; T302-I305 PolarHBondContact O-N 3.27Å; T302-A306 WeakPolarHBondContact O-CB 3.34Å; T302-A306 PolarHBondContact O-N 2.94Å; T302-L364 HydrophobicContact CG2-CD2 4.22Å; T302-G365 WeakPolarHBondContact OG1-CA 3.4Å; T302-F442 HydrophobicContact CG2-CB 3.51Å; T302-M443 HydrophobicContact CG2-SD 3.35Å; T302-M443 WeakPolarHBondContact CG2-SD 3.13Å
303	L	96.2	Very high	95.6	Very high	0 Å²	0	13.7 Å²	13.7	0%	0	6%	0.059	C	C	.	.	H	α-helix	trans	-65.8	-36.6	175.9	-157.1	98.1	0	0	0	112.5	H281 V285 G299 Y301 I305 A306 H307 E366 L369	H281-L303 HydrophobicContact CB-CD2 4.31Å; V285-L303 HydrophobicContact CG2-CB 4.03Å; V285-L303 HydrophobicContact CG2-CD2 3.17Å; V285-L303 HydrophobicContact CG2-CG 4.16Å; G299-L303 WeakPolarHBondContact O-CB 3.4Å; G299-L303 PolarHBondContact O-N 3.47Å; Y301-L303 VanDerWaalsContact C-N 3.34Å; Y301-L303 PolarHBondContact O-N 2.87Å; L303-I305 VanDerWaalsContact C-N 3.32Å; L303-I305 PolarHBondContact O-N 3.25Å; L303-A306 PolarHBondContact O-N 3.48Å; L303-H307 WeakPolarHBondContact O-CB 3.45Å; L303-H307 PolarHBondContact O-N 2.71Å; L303-E366 HydrophobicContact CD1-CB 4.4Å; L303-E366 HydrophobicContact CD1-CG 3.36Å; L303-L369 HydrophobicContact CB-CD1 3.99Å; L303-L369 HydrophobicContact CD1-CD1 4.32Å; L303-L369 HydrophobicContact CD2-CD1 4.06Å; L303-L369 HydrophobicContact CG-CD1 4.34Å
304	M	96.6	Very high	95.7	Very high	0 Å²	0	12 Å²	12	0%	0	5%	0.048	C	C	.	.	H	α-helix	trans	-58.4	-44.1	175.9	-84	-168.5	-62.9	0	0	111.8	K225 L232 V285 S300 Y301 T302 G308	K225-M304 HydrophobicContact CB-SD 4.41Å; K225-M304 WeakPolarHBondContact CE-O 3.38Å; K225-M304 HydrophobicContact CG-CB 3.88Å; K225-M304 HydrophobicContact CG-CG 4.1Å; K225-M304 HydrophobicContact CG-SD 4.29Å; L232-M304 HydrophobicContact CD1-CE 3.57Å; V285-M304 HydrophobicContact CG1-CG 4.04Å; S300-M304 WeakPolarHBondContact O-CB 3.31Å; S300-M304 VanDerWaalsContact O-CG 3.26Å; S300-M304 WeakPolarHBondContact O-CG 3.16Å; S300-M304 PolarHBondContact O-N 3.1Å; Y301-M304 HydrophobicContact CD2-CE 4.23Å; Y301-M304 WeakPolarHBondContact O-CB 3.45Å; Y301-M304 PolarHBondContact O-N 3.24Å; T302-M304 PolarHBondContact O-N 3.21Å; M304-G308 PolarHBondContact O-N 3.28Å
305	I	95.9	Very high	95.9	Very high	4 Å²	4	7.8 Å²	7.8	2%	0.021	3%	0.032	C	C	.	.	H	α-helix	trans	-70	-49.2	178.5	-63.9	172.8	0	0	0	110.4	L64 Y301 T302 L303 H307 G308 L309 L361 L435 F442	L64-I305 HydrophobicContact CD1-CG2 4.5Å; Y301-I305 HydrophobicContact CD1-CD1 4.35Å; Y301-I305 HydrophobicContact CD2-CD1 4.25Å; Y301-I305 HydrophobicContact CE1-CD1 3.87Å; Y301-I305 HydrophobicContact CE2-CD1 3.78Å; Y301-I305 HydrophobicContact CE2-CG1 4.38Å; Y301-I305 PolarHBondContact O-N 3.37Å; Y301-I305 VanDerWaalsContact O-N 3.14Å; T302-I305 PolarHBondContact O-N 3.27Å; L303-I305 VanDerWaalsContact C-N 3.32Å; L303-I305 PolarHBondContact O-N 3.25Å; I305-H307 PolarHBondContact O-N 3.07Å; I305-G308 PolarHBondContact O-N 3.36Å; I305-G308 VanDerWaalsContact O-N 3.16Å; I305-L309 PolarHBondContact O-N 3.42Å; I305-L361 HydrophobicContact CB-CD2 4.32Å; I305-L361 HydrophobicContact CG2-CD2 4.11Å; I305-L435 HydrophobicContact CG2-CD1 4.39Å; I305-F442 HydrophobicContact CD1-CD1 3.26Å; I305-F442 HydrophobicContact CD1-CE1 3.32Å; I305-F442 HydrophobicContact CD1-CG 4.3Å; I305-F442 HydrophobicContact CD1-CZ 4.38Å
306	A	96.1	Very high	96	Very high	0 Å²	0	1.7 Å²	1.7	0%	0	1%	0.009	C	C	.	.	H	α-helix	trans	-60.5	-49.2	-177.7	0	0	0	0	0	111.8	T302 L303 G308 L309 C310 L361 N362	T302-A306 WeakPolarHBondContact O-CB 3.34Å; T302-A306 PolarHBondContact O-N 2.94Å; L303-A306 PolarHBondContact O-N 3.48Å; A306-G308 VanDerWaalsContact C-N 3.29Å; A306-G308 PolarHBondContact O-N 2.62Å; A306-L309 PolarHBondContact O-N 3.28Å; A306-C310 WeakPolarHBondContact O-CB 3.2Å; A306-C310 PolarHBondContact O-N 3.35Å; A306-L361 HydrophobicContact CB-CB 3.7Å; A306-L361 HydrophobicContact CB-CD2 3.6Å; A306-L361 HydrophobicContact CB-CG 3.88Å; A306-N362 HydrophobicContact CB-CB 4.38Å; A306-N362 WeakPolarHBondContact CB-OD1 2.88Å
307	H	96.5	Very high	96.1	Very high	1 Å²	1	1.7 Å²	1.7	1%	0.005	1%	0.009	C	C	.	.	H	α-helix	trans	-66.6	-31.7	177.4	-172.4	79.2	0	0	0	111.7	S278 H281 M282 L303 I305 L309 C310 S311 N362	S278-H307 WeakPolarHBondContact CA-NE2 3.4Å; S278-H307 WeakPolarHBondContact CB-NE2 3.37Å; H281-H307 AromaticContact CD2-CE1 3.62Å; H281-H307 AromaticContact CD2-ND1 3.72Å; H281-H307 AromaticContact CG-CE1 3.96Å; H281-H307 AromaticContact CG-ND1 3.75Å; M282-H307 HydrophobicContact CE-CB 4.18Å; M282-H307 WeakPolarHBondContact CE-CD2 3.47Å; L303-H307 WeakPolarHBondContact O-CB 3.45Å; L303-H307 PolarHBondContact O-N 2.71Å; I305-H307 PolarHBondContact O-N 3.07Å; H307-L309 VanDerWaalsContact C-N 3.35Å; H307-L309 PolarHBondContact O-N 2.96Å; H307-C310 PolarHBondContact O-N 2.91Å; H307-S311 VanDerWaalsContact O-CB 3.27Å; H307-S311 WeakPolarHBondContact O-CB 3.32Å; H307-S311 PolarHBondContact O-N 3.48Å; H307-S311 PolarHBondContact O-OG 2.89Å; H307-N362 PolarHBondContact N-OD1 3.37Å
308	G	96.3	Very high	96.1	Very high	0 Å²	0	0.9 Å²	0.9	0%	0	1%	0.005	C	C	.	.	H	α-helix	trans	-56.9	-44.5	172.9	0	0	0	0	0	113.3	K225 M304 I305 A306 S312	K225-G308 VanDerWaalsContact NZ-CA 3.33Å; M304-G308 PolarHBondContact O-N 3.28Å; I305-G308 PolarHBondContact O-N 3.36Å; I305-G308 VanDerWaalsContact O-N 3.16Å; A306-G308 VanDerWaalsContact C-N 3.29Å; A306-G308 PolarHBondContact O-N 2.62Å; G308-S312 WeakPolarHBondContact O-CB 3.37Å; G308-S312 PolarHBondContact O-OG 3.48Å
309	L	96.3	Very high	96.1	Very high	4 Å²	4	1 Å²	1	2%	0.021	1%	0.006	C	C	.	.	H	α-helix	trans	-75.8	-41.4	176.8	-66.3	170.7	0	0	0	112.5	L64 I305 A306 H307 S312 G313 H428 P431 L432 L435	L64-L309 HydrophobicContact CD1-CD2 3.77Å; L64-L309 HydrophobicContact CD1-CG 3.76Å; I305-L309 PolarHBondContact O-N 3.42Å; A306-L309 PolarHBondContact O-N 3.28Å; H307-L309 VanDerWaalsContact C-N 3.35Å; H307-L309 PolarHBondContact O-N 2.96Å; L309-S312 PolarHBondContact O-OG 2.81Å; L309-G313 PolarHBondContact O-N 3.32Å; L309-H428 PolarHBondContact O-CD2 3.16Å; L309-P431 HydrophobicContact CD1-CB 4Å; L309-L432 HydrophobicContact CB-CD1 4.36Å; L309-L432 HydrophobicContact CD1-CB 4.4Å; L309-L435 HydrophobicContact CD1-CD1 4.34Å
310	C	96.5	Very high	96.1	Very high	0 Å²	0	1.1 Å²	1.1	0%	0	1%	0.006	C	C	.	.	H	α-helix	trans	-66.3	-51	-178.2	-170.6	0	0	0	0	112.5	A306 H307 G313 L314 L432	A306-C310 WeakPolarHBondContact O-CB 3.2Å; A306-C310 PolarHBondContact O-N 3.35Å; H307-C310 PolarHBondContact O-N 2.91Å; C310-G313 PolarHBondContact O-N 2.94Å; C310-L314 WeakPolarHBondContact O-CG 3.48Å; C310-L314 PolarHBondContact O-N 2.91Å; C310-L432 HydrophobicContact CB-CD1 3.76Å
311	S	96.4	Very high	95.9	Very high	1 Å²	1	1.2 Å²	1.2	1%	0.007	1%	0.007	C	C	.	.	H	α-helix	trans	-66	-40.3	-176.9	59	0	0	0	0	112.4	H307 G313 L314 F315	H307-S311 VanDerWaalsContact O-CB 3.27Å; H307-S311 WeakPolarHBondContact O-CB 3.32Å; H307-S311 PolarHBondContact O-N 3.48Å; H307-S311 PolarHBondContact O-OG 2.89Å; S311-G313 VanDerWaalsContact C-N 3.32Å; S311-G313 PolarHBondContact O-N 2.95Å; S311-L314 PolarHBondContact O-N 3.47Å; S311-F315 WeakPolarHBondContact O-CD2 3.29Å; S311-F315 PolarHBondContact O-N 3.31Å
312	S	96.8	Very high	95.8	Very high	0 Å²	0	3.3 Å²	3.3	0%	0	2%	0.015	C	C	.	.	H	α-helix	trans	-62.1	-39.5	174.6	52.5	0	0	0	0	112	G308 L309 F315 C316 H428	G308-S312 WeakPolarHBondContact O-CB 3.37Å; G308-S312 PolarHBondContact O-OG 3.48Å; L309-S312 PolarHBondContact O-OG 2.81Å; S312-F315 PolarHBondContact O-N 3.35Å; S312-C316 PolarHBondContact O-N 2.95Å; S312-H428 PolarHBondContact OG-CD2 3.06Å; S312-H428 VanDerWaalsContact OG-CD2 3.23Å; S312-H428 PolarHBondContact OG-NE2 3.04Å
313	G	96.9	Very high	95.5	Very high	0 Å²	0	5.5 Å²	5.5	0%	0	3%	0.026	C	C	.	.	H	α-helix	trans	-63	-44.2	173.3	0	0	0	0	0	113.1	L309 C310 S311 C316 L317 L350 H428	L309-G313 PolarHBondContact O-N 3.32Å; C310-G313 PolarHBondContact O-N 2.94Å; S311-G313 VanDerWaalsContact C-N 3.32Å; S311-G313 PolarHBondContact O-N 2.95Å; G313-C316 PolarHBondContact O-N 2.88Å; G313-C316 VanDerWaalsContact O-N 3.17Å; G313-L317 PolarHBondContact O-N 3.27Å; G313-L350 VanDerWaalsContact C-CD1 3.49Å; G313-H428 PolarHBondContact N-CD2 3.45Å; G313-H428 VanDerWaalsContact N-CD2 3.25Å
314	L	96.8	Very high	95.2	Very high	1 Å²	1	7 Å²	7	1%	0.005	3%	0.031	C	C	.	.	H	α-helix	trans	-62.7	-41.7	176.3	-71	174.7	0	0	0	112.3	I274 C310 S311 C316 L317 A318 L350 N354	I274-L314 HydrophobicContact CD1-CB 4.07Å; I274-L314 HydrophobicContact CG1-CB 4.33Å; I274-L314 HydrophobicContact CG2-CB 4Å; C310-L314 WeakPolarHBondContact O-CG 3.48Å; C310-L314 PolarHBondContact O-N 2.91Å; S311-L314 PolarHBondContact O-N 3.47Å; L314-C316 VanDerWaalsContact C-N 3.27Å; L314-C316 PolarHBondContact O-N 2.94Å; L314-L317 HydrophobicContact CD2-CD1 4.42Å; L314-L317 PolarHBondContact O-N 3.05Å; L314-A318 PolarHBondContact O-N 3.18Å; L314-L350 HydrophobicContact CD2-CB 3.91Å; L314-L350 HydrophobicContact CG-CB 4.46Å; L314-N354 HydrophobicContact CD1-CB 4.1Å
315	F	97.2	Very high	94.9	Very high	1 Å²	1	8.2 Å²	8.2	0%	0.004	4%	0.037	C	C	.	.	H	α-helix	trans	-62.7	-34.9	174.3	-81.3	-64.8	0	0	0	112.2	H208 A220 K271 I274 A275 S311 S312 N319	H208-F315 HydrophobicContact CB-CE1 4.09Å; H208-F315 HydrophobicContact CB-CZ 4.01Å; H208-F315 AromaticContact CE1-CE2 3.8Å; H208-F315 AromaticContact CE1-CZ 3.92Å; H208-F315 AromaticContact CG-CZ 3.7Å; H208-F315 AromaticContact ND1-CE1 3.81Å; H208-F315 AromaticContact ND1-CE2 3.51Å; H208-F315 AromaticContact ND1-CZ 3.23Å; H208-F315 WeakPolarHBondContact ND1-CZ 3.49Å; A220-F315 HydrophobicContact CB-CD2 3.75Å; A220-F315 HydrophobicContact CB-CE2 3.61Å; K271-F315 HydrophobicContact CB-CE1 4.44Å; I274-F315 HydrophobicContact CB-CD1 4.5Å; I274-F315 HydrophobicContact CB-CE1 4.02Å; I274-F315 HydrophobicContact CB-CE2 4.5Å; I274-F315 HydrophobicContact CB-CZ 4.01Å; I274-F315 HydrophobicContact CG2-CD1 4.2Å; I274-F315 HydrophobicContact CG2-CD2 3.91Å; I274-F315 HydrophobicContact CG2-CE1 3.9Å; I274-F315 HydrophobicContact CG2-CE2 3.57Å; I274-F315 HydrophobicContact CG2-CG 4.2Å; I274-F315 HydrophobicContact CG2-CZ 3.57Å; A275-F315 HydrophobicContact CB-CZ 4.25Å; S311-F315 WeakPolarHBondContact O-CD2 3.29Å; S311-F315 PolarHBondContact O-N 3.31Å; S312-F315 PolarHBondContact O-N 3.35Å; F315-N319 PolarHBondContact O-N 3.01Å
316	C	95.9	Very high	94.5	Very high	3 Å²	3	10.6 Å²	10.6	2%	0.02	6%	0.063	C	C	.	.	H	α-helix	trans	-69	-40.9	174.1	-167.6	0	0	0	0	112.4	S312 G313 L314 A318 N319 V320 L424 M425	S312-C316 PolarHBondContact O-N 2.95Å; G313-C316 PolarHBondContact O-N 2.88Å; G313-C316 VanDerWaalsContact O-N 3.17Å; L314-C316 VanDerWaalsContact C-N 3.27Å; L314-C316 PolarHBondContact O-N 2.94Å; C316-A318 VanDerWaalsContact C-N 3.32Å; C316-A318 PolarHBondContact O-N 3.44Å; C316-N319 WeakPolarHBondContact O-CB 3.48Å; C316-N319 PolarHBondContact O-N 3.35Å; C316-N319 VanDerWaalsContact O-N 3.12Å; C316-V320 WeakPolarHBondContact O-CG2 3.38Å; C316-V320 PolarHBondContact O-N 2.85Å; C316-L424 HydrophobicContact CB-CD2 3.52Å; C316-L424 VanDerWaalsContact SG-CD1 3.51Å; C316-L424 WeakPolarHBondContact SG-CD2 3.23Å; C316-M425 HydrophobicContact CB-SD 4.41Å
317	L	95.5	Very high	94.2	Very high	0 Å²	0	11.6 Å²	11.6	0%	0	7%	0.07	C	C	.	.	H	α-helix	trans	-60.1	-43.5	174	-76.2	173.8	0	0	0	112	G313 L314 N319 V320 S321 W346 W347 L350 M425	G313-L317 PolarHBondContact O-N 3.27Å; L314-L317 HydrophobicContact CD2-CD1 4.42Å; L314-L317 PolarHBondContact O-N 3.05Å; L317-N319 VanDerWaalsContact C-N 3.28Å; L317-N319 PolarHBondContact O-N 3.21Å; L317-V320 PolarHBondContact O-N 3.33Å; L317-S321 PolarHBondContact O-N 2.82Å; L317-W346 HydrophobicContact CD2-CB 4.23Å; L317-W347 HydrophobicContact CB-CD2 3.98Å; L317-W347 HydrophobicContact CB-CE3 4.19Å; L317-W347 HydrophobicContact CB-CH2 3.79Å; L317-W347 HydrophobicContact CB-CZ2 3.56Å; L317-W347 HydrophobicContact CB-CZ3 4.08Å; L317-W347 HydrophobicContact CD1-CB 4.4Å; L317-W347 HydrophobicContact CD1-CD2 3.74Å; L317-W347 HydrophobicContact CD1-CE3 3.87Å; L317-W347 HydrophobicContact CD1-CG 3.95Å; L317-W347 HydrophobicContact CD1-CZ3 4.42Å; L317-W347 HydrophobicContact CD2-CD2 4.43Å; L317-W347 HydrophobicContact CD2-CG 4.31Å; L317-W347 HydrophobicContact CG-CD2 4.28Å; L317-W347 WeakPolarHBondContact O-CZ2 3.49Å; L317-L350 HydrophobicContact CD1-CB 4.23Å; L317-L350 HydrophobicContact CD1-CD1 3.76Å; L317-L350 HydrophobicContact CD1-CG 4.47Å; L317-L350 HydrophobicContact CG-CD1 4.37Å; L317-M425 HydrophobicContact CD1-CE 3.79Å; L317-M425 HydrophobicContact CD2-CE 3.58Å; L317-M425 HydrophobicContact CD2-CG 4.12Å; L317-M425 HydrophobicContact CD2-SD 3.66Å; L317-M425 HydrophobicContact CG-CE 3.34Å; L317-M425 HydrophobicContact CG-SD 3.83Å
318	A	95.7	Very high	94	Very high	2 Å²	2	13.2 Å²	13.2	2%	0.017	8%	0.076	C	C	.	.	H	α-helix	trans	-59.2	-41.7	173.6	0	0	0	0	0	111.1	K271 I274 L314 C316 S321 Y322	K271-A318 HydrophobicContact CG-CB 4.36Å; I274-A318 HydrophobicContact CD1-CB 3.81Å; L314-A318 PolarHBondContact O-N 3.18Å; C316-A318 VanDerWaalsContact C-N 3.32Å; C316-A318 PolarHBondContact O-N 3.44Å; A318-S321 PolarHBondContact O-N 3.28Å; A318-S321 PolarHBondContact O-OG 3.29Å; A318-Y322 WeakPolarHBondContact O-CB 3.43Å; A318-Y322 PolarHBondContact O-N 3.21Å
319	N	95	Very high	93.9	Very high	2 Å²	2	14.4 Å²	14.4	1%	0.011	9%	0.085	C	C	.	.	H	α-helix	trans	-64.9	-42.3	174.9	-179.8	60.5	0	0	0	113.2	V213 F315 C316 L317 S321 Y322 E323	V213-N319 HydrophobicContact CB-CB 4.26Å; V213-N319 HydrophobicContact CG1-CB 3.66Å; V213-N319 HydrophobicContact CG2-CB 3.59Å; V213-N319 VanDerWaalsContact CG2-ND2 3.34Å; V213-N319 WeakPolarHBondContact CG2-ND2 3.33Å; V213-N319 WeakPolarHBondContact CG2-OD1 3.39Å; F315-N319 PolarHBondContact O-N 3.01Å; C316-N319 WeakPolarHBondContact O-CB 3.48Å; C316-N319 PolarHBondContact O-N 3.35Å; C316-N319 VanDerWaalsContact O-N 3.12Å; L317-N319 VanDerWaalsContact C-N 3.28Å; L317-N319 PolarHBondContact O-N 3.21Å; N319-S321 PolarHBondContact O-N 2.89Å; N319-Y322 CarbonylContact O-C 3.5Å; N319-Y322 WeakPolarHBondContact O-CA 3.49Å; N319-Y322 WeakPolarHBondContact O-CB 3.36Å; N319-Y322 PolarHBondContact O-N 3.17Å; N319-E323 PolarHBondContact ND2-OE1 3.01Å; N319-E323 PolarHBondContact O-N 3.33Å
320	V	93.9	Very high	93.7	Very high	2 Å²	2	14.4 Å²	14.4	1%	0.012	9%	0.085	C	C	.	.	H	α-helix	trans	-60.7	-36.2	178.2	166.5	0	0	0	0	110.9	C316 L317 R324 M343 E421	C316-V320 WeakPolarHBondContact O-CG2 3.38Å; C316-V320 PolarHBondContact O-N 2.85Å; L317-V320 PolarHBondContact O-N 3.33Å; V320-R324 VanDerWaalsContact CG1-CZ 3.47Å; V320-R324 PolarHBondContact O-NH1 3.41Å; V320-R324 VanDerWaalsContact O-NH1 3.16Å; V320-M343 HydrophobicContact CG1-CE 4.42Å; V320-E421 HydrophobicContact CG2-CB 4.31Å; V320-E421 HydrophobicContact CG2-CG 3.98Å
321	S	92.7	Very high	93.4	Very high	2 Å²	2	19.3 Å²	19.3	1%	0.014	11%	0.11	C	C	.	.	H	α-helix	trans	-68.4	-39.9	169.9	70.3	0	0	0	0	112.9	L317 A318 N319 R324 L325 N333	L317-S321 PolarHBondContact O-N 2.82Å; A318-S321 PolarHBondContact O-N 3.28Å; A318-S321 PolarHBondContact O-OG 3.29Å; N319-S321 PolarHBondContact O-N 2.89Å; S321-R324 PolarHBondContact O-N 2.9Å; S321-L325 PolarHBondContact O-N 3.02Å; S321-N333 PolarHBondContact OG-ND2 3.24Å
322	Y	92.6	Very high	93.2	Very high	46 Å²	46	21.7 Å²	21.7	18%	0.18	12%	0.122	C	C	.	.	H	α-helix	trans	-66	-41.7	179	178.9	-101.9	0	0	0	112.9	Y132 A318 N319 R324 G326 R328	Y132-Y322 HydrophobicContact CD1-CE1 4.21Å; Y132-Y322 HydrophobicContact CD2-CE1 4.33Å; Y132-Y322 HydrophobicContact CE1-CE1 4.07Å; Y132-Y322 HydrophobicContact CE2-CE1 4.2Å; Y132-Y322 HydrophobicContact CG-CE1 4.34Å; A318-Y322 WeakPolarHBondContact O-CB 3.43Å; A318-Y322 PolarHBondContact O-N 3.21Å; N319-Y322 CarbonylContact O-C 3.5Å; N319-Y322 WeakPolarHBondContact O-CA 3.49Å; N319-Y322 WeakPolarHBondContact O-CB 3.36Å; N319-Y322 PolarHBondContact O-N 3.17Å; Y322-R324 PolarHBondContact O-N 3.15Å; Y322-G326 VanDerWaalsContact O-CA 3.27Å; Y322-G326 WeakPolarHBondContact O-CA 3.12Å; Y322-G326 PolarHBondContact O-N 3.22Å; Y322-R328 HydrophobicContact CD2-CG 3.71Å; Y322-R328 HydrophobicContact CE2-CG 3.86Å
323	E	90.4	Very high	92.9	Very high	47 Å²	47	21.7 Å²	21.7	22%	0.22	12%	0.122	C	C	.	.	H	α-helix	trans	-60.3	-26.3	177.9	-76.7	-176.7	-168.1	0	0	112.8	M78 N319 R420	M78-E323 HydrophobicContact CG-CG 4.25Å; M78-E323 WeakPolarHBondContact CG-OE1 3.16Å; N319-E323 PolarHBondContact ND2-OE1 3.01Å; N319-E323 PolarHBondContact O-N 3.33Å; E323-R420 IonicContact OE2-NH2 3.91Å
324	R	89.4	Confident	92.6	Very high	30 Å²	30	24.8 Å²	24.8	11%	0.113	14%	0.136	C	C	.	.	H	α-helix	trans	-93.4	-49.2	179.5	-59.8	-171.5	-165.4	100.4	-0.3	112.4	V320 S321 Y322 M340 S413 S415 E421	V320-R324 VanDerWaalsContact CG1-CZ 3.47Å; V320-R324 PolarHBondContact O-NH1 3.41Å; V320-R324 VanDerWaalsContact O-NH1 3.16Å; S321-R324 PolarHBondContact O-N 2.9Å; Y322-R324 PolarHBondContact O-N 3.15Å; R324-M340 PolarHBondContact NH1-SD 2.96Å; R324-S413 WeakPolarHBondContact O-CB 3.23Å; R324-S413 PolarHBondContact O-OG 3.14Å; R324-S415 WeakPolarHBondContact CD-O 3.34Å; R324-S415 WeakPolarHBondContact CD-OG 3.28Å; R324-S415 PolarHBondContact NE-O 3.16Å; R324-S415 PolarHBondContact NE-OG 3.17Å; R324-S415 VanDerWaalsContact NE-OG 3.07Å; R324-E421 IonicContact CZ-OE2 3.88Å; R324-E421 IonicContact NH2-OE2 2.73Å; R324-E421 PolarHBondContact NH2-OE2 3.09Å
325	L	89.4	Confident	92.2	Very high	26 Å²	26	24.7 Å²	24.7	14%	0.136	14%	0.136	C	C	.	.	H	α-helix	trans	-91	-13.8	-172.2	-60.2	178.9	0	0	0	113.2	S321 S327 N333 L336 V411	S321-L325 PolarHBondContact O-N 3.02Å; L325-S327 PolarHBondContact O-N 3.38Å; L325-S327 VanDerWaalsContact O-N 3.12Å; L325-N333 HydrophobicContact CD1-CB 3.89Å; L325-N333 VanDerWaalsContact CD1-CG 3.49Å; L325-N333 WeakPolarHBondContact CD1-OD1 3.34Å; L325-L336 HydrophobicContact CD1-CD2 3.97Å; L325-V411 HydrophobicContact CD2-CB 4.15Å; L325-V411 HydrophobicContact CD2-CG1 3.53Å; L325-V411 HydrophobicContact CD2-CG2 4.46Å
326	G	88.1	Confident	91.9	Very high	55 Å²	55	25 Å²	25	57%	0.567	14%	0.137	S	C	*	.	S	Bend	trans	68.7	4.5	-179.6	0	0	0	0	0	114.6	Y322	Y322-G326 VanDerWaalsContact O-CA 3.27Å; Y322-G326 WeakPolarHBondContact O-CA 3.12Å; Y322-G326 PolarHBondContact O-N 3.22Å
327	S	90.6	Very high	91.8	Very high	20 Å²	20	27.9 Å²	27.9	14%	0.14	15%	0.152	C	C	.	.			trans	-132.1	148.1	-175.6	100.4	0	0	0	0	112	L325 I332 N333	L325-S327 PolarHBondContact O-N 3.38Å; L325-S327 VanDerWaalsContact O-N 3.12Å; S327-I332 VanDerWaalsContact OG-CB 3.27Å; S327-I332 WeakPolarHBondContact OG-CB 3.46Å; S327-I332 WeakPolarHBondContact OG-CD1 3.47Å; S327-I332 WeakPolarHBondContact OG-CG2 3.31Å; S327-N333 PolarHBondContact O-ND2 2.76Å; S327-N333 VanDerWaalsContact O-ND2 3.11Å; S327-N333 PolarHBondContact O-OD1 2.66Å; S327-N333 PolarHBondContact OG-OD1 3.27Å
328	R	91.4	Very high	91.5	Very high	35 Å²	35	33 Å²	33	13%	0.132	18%	0.179	C	C	.	.			trans	-92.6	-9	177.7	-57.1	-177	-60.3	-156.6	0.8	112.9	Q133 V209 E210 L270 Y322	Q133-R328 VanDerWaalsContact CD-CZ 3.41Å; Q133-R328 VanDerWaalsContact CD-NH1 3.28Å; Q133-R328 VanDerWaalsContact NE2-CZ 3.3Å; V209-R328 PolarHBondContact O-NH1 3.28Å; E210-R328 IonicContact OE1-CZ 3.71Å; E210-R328 IonicContact OE1-NH1 3.48Å; E210-R328 PolarHBondContact OE1-NH1 3.14Å; E210-R328 IonicContact OE1-NH2 2.82Å; E210-R328 PolarHBondContact OE1-NH2 3.11Å; E210-R328 IonicContact OE2-NH1 3.23Å; L270-R328 WeakPolarHBondContact CB-O 3.47Å; L270-R328 PolarHBondContact N-O 3.13Å; Y322-R328 HydrophobicContact CD2-CG 3.71Å; Y322-R328 HydrophobicContact CE2-CG 3.86Å
329	S	93.8	Very high	91	Very high	26 Å²	26	36.2 Å²	36.2	18%	0.182	19%	0.193	C	C	.	.	B	Isolated β-bridge	trans	-75.5	135.5	-171.5	77.1	0	0	0	0	111.7	L331 I332 N333	S329-L331 PolarHBondContact O-N 3.25Å; S329-I332 PolarHBondContact O-N 2.97Å; S329-I332 WeakPolarHBondContact OG-CB 3.35Å; S329-I332 WeakPolarHBondContact OG-CD1 3.4Å; S329-I332 VanDerWaalsContact OG-CG1 3.25Å; S329-I332 WeakPolarHBondContact OG-CG1 3.35Å; S329-I332 PolarHBondContact OG-N 3.48Å; S329-N333 WeakPolarHBondContact O-CB 3.38Å; S329-N333 PolarHBondContact O-N 3.35Å
330	M	92.4	Very high	90.7	Very high	3 Å²	3	36.2 Å²	36.2	2%	0.015	19%	0.193	C	C	.	.	T	Hydrogen-bonded Turn	trans	-59.4	-26.8	172.8	-71.8	-69.7	-67.7	0	0	112.2	T268 L270 K334 F401	T268-M330 VanDerWaalsContact O-CB 3.25Å; T268-M330 WeakPolarHBondContact O-CB 3.45Å; T268-M330 WeakPolarHBondContact O-CG 3.48Å; T268-M330 PolarHBondContact O-N 3.47Å; L270-M330 HydrophobicContact CB-SD 4.46Å; L270-M330 HydrophobicContact CD1-SD 4.33Å; L270-M330 HydrophobicContact CD2-CE 4.43Å; L270-M330 HydrophobicContact CD2-CG 4.41Å; L270-M330 HydrophobicContact CD2-SD 3.08Å; L270-M330 WeakPolarHBondContact CD2-SD 3.13Å; L270-M330 HydrophobicContact CG-CG 4.12Å; L270-M330 HydrophobicContact CG-SD 3.35Å; L270-M330 WeakPolarHBondContact CG-SD 3.37Å; M330-K334 WeakPolarHBondContact O-CG 3.31Å; M330-F401 HydrophobicContact CE-CB 3.33Å; M330-F401 HydrophobicContact CE-CG 4.47Å
331	L	90.6	Very high	90.6	Very high	104 Å²	104	39.8 Å²	39.8	55%	0.545	22%	0.216	S	C	.	.	T	Hydrogen-bonded Turn	trans	-72.9	-36.3	-177.3	-64.9	177	0	0	0	113.2	S329 K334	S329-L331 PolarHBondContact O-N 3.25Å; L331-K334 WeakPolarHBondContact O-CD 3.01Å; L331-K334 WeakPolarHBondContact O-CG 3.23Å
332	I	91.8	Very high	90.5	Very high	50 Å²	50	42.1 Å²	42.1	26%	0.256	23%	0.232	S	C	.	.	T	Hydrogen-bonded Turn	trans	-80.5	-36.9	176.3	-64.8	169.6	0	0	0	109.8	S327 S329 K334 F408 V411	S327-I332 VanDerWaalsContact OG-CB 3.27Å; S327-I332 WeakPolarHBondContact OG-CB 3.46Å; S327-I332 WeakPolarHBondContact OG-CD1 3.47Å; S327-I332 WeakPolarHBondContact OG-CG2 3.31Å; S329-I332 PolarHBondContact O-N 2.97Å; S329-I332 WeakPolarHBondContact OG-CB 3.35Å; S329-I332 WeakPolarHBondContact OG-CD1 3.4Å; S329-I332 VanDerWaalsContact OG-CG1 3.25Å; S329-I332 WeakPolarHBondContact OG-CG1 3.35Å; S329-I332 PolarHBondContact OG-N 3.48Å; I332-K334 PolarHBondContact O-N 3.12Å; I332-F408 HydrophobicContact CG2-CD1 4.24Å; I332-V411 HydrophobicContact CG2-CG2 4.25Å
333	N	90.6	Very high	90.6	Very high	0 Å²	0	39.9 Å²	39.9	0%	0	22%	0.224	C	C	.	.	S	Bend	trans	-83.5	37.9	-174	-62.3	3.3	0	0	0	113.5	L270 S321 L325 S327 S329 L336 S402	L270-N333 HydrophobicContact CD1-CB 3.87Å; L270-N333 WeakPolarHBondContact CD1-ND2 3.16Å; S321-N333 PolarHBondContact OG-ND2 3.24Å; L325-N333 HydrophobicContact CD1-CB 3.89Å; L325-N333 VanDerWaalsContact CD1-CG 3.49Å; L325-N333 WeakPolarHBondContact CD1-OD1 3.34Å; S327-N333 PolarHBondContact O-ND2 2.76Å; S327-N333 VanDerWaalsContact O-ND2 3.11Å; S327-N333 PolarHBondContact O-OD1 2.66Å; S327-N333 PolarHBondContact OG-OD1 3.27Å; S329-N333 WeakPolarHBondContact O-CB 3.38Å; S329-N333 PolarHBondContact O-N 3.35Å; N333-L336 HydrophobicContact CB-CD1 4.4Å; N333-S402 CarbonylContact O-C 3.55Å; N333-S402 VanDerWaalsContact O-CA 3.26Å; N333-S402 WeakPolarHBondContact O-CA 3.38Å
334	K	90	Very high	90.8	Very high	65 Å²	65	38.1 Å²	38.1	28%	0.283	22%	0.216	S	C	.	.			trans	-92.7	150.7	-178.5	-65.3	-174.2	165	169.5	0	113	M330 L331 I332 L336 F401 S402 L407	M330-K334 WeakPolarHBondContact O-CG 3.31Å; L331-K334 WeakPolarHBondContact O-CD 3.01Å; L331-K334 WeakPolarHBondContact O-CG 3.23Å; I332-K334 PolarHBondContact O-N 3.12Å; K334-L336 VanDerWaalsContact C-N 3.33Å; K334-L336 PolarHBondContact O-N 3.26Å; K334-F401 WeakPolarHBondContact CG-O 3.43Å; K334-S402 CarbonylContact C-O 3.45Å; K334-L407 WeakPolarHBondContact O-CD2 3.24Å
335	G	90	Very high	91	Very high	0 Å²	0	41.3 Å²	41.3	0%	0	24%	0.235	C	C	.	.			trans	72.5	18.4	170.7	0	0	0	0	0	115.6	L337 N338 S402 Q403 H404 G405 L407	G335-L337 PolarHBondContact O-N 2.72Å; G335-N338 PolarHBondContact O-N 3.11Å; G335-S402 PolarHBondContact N-O 3.28Å; G335-S402 VanDerWaalsContact N-O 3.17Å; G335-Q403 CarbonylContact C-O 3.16Å; G335-Q403 VanDerWaalsContact CA-O 3.27Å; G335-Q403 WeakPolarHBondContact CA-O 3.48Å; G335-H404 WeakPolarHBondContact CA-O 3.47Å; G335-H404 PolarHBondContact N-O 2.86Å; G335-H404 VanDerWaalsContact N-O 3.08Å; G335-G405 WeakPolarHBondContact CA-O 2.85Å; G335-L407 WeakPolarHBondContact O-CD2 3.46Å
336	L	91	Very high	91.3	Very high	8 Å²	8	41.7 Å²	41.7	4%	0.042	23%	0.234	C	C	.	.	G	3₁₀ helix	trans	-57.5	-17.7	-173.3	-71.4	170	0	0	0	114.6	L325 N333 K334 N338 F339 M340 S402 Q403	L325-L336 HydrophobicContact CD1-CD2 3.97Å; N333-L336 HydrophobicContact CB-CD1 4.4Å; K334-L336 VanDerWaalsContact C-N 3.33Å; K334-L336 PolarHBondContact O-N 3.26Å; L336-N338 PolarHBondContact O-N 3.45Å; L336-F339 PolarHBondContact O-N 3.31Å; L336-F339 VanDerWaalsContact O-N 3.12Å; L336-M340 HydrophobicContact CB-CE 3.75Å; L336-M340 HydrophobicContact CB-CG 4.43Å; L336-M340 HydrophobicContact CD1-CE 3.61Å; L336-M340 HydrophobicContact CD2-CE 3.85Å; L336-M340 HydrophobicContact CG-CE 3.92Å; L336-M340 WeakPolarHBondContact O-CG 3.1Å; L336-M340 PolarHBondContact O-N 3.45Å; L336-S402 PolarHBondContact N-O 3.28Å; L336-Q403 PolarHBondContact N-O 2.93Å
337	L	92.9	Very high	91.7	Very high	63 Å²	63	39.1 Å²	39.1	33%	0.33	21%	0.208	S	C	.	.	G	3₁₀ helix	trans	-58.4	-34.3	173.3	-170.3	144	0	0	0	113.5	G335 F339 T344 Q403	G335-L337 PolarHBondContact O-N 2.72Å; L337-F339 VanDerWaalsContact C-N 3.32Å; L337-F339 PolarHBondContact O-N 3.06Å; L337-T344 HydrophobicContact CB-CG2 4.01Å; L337-T344 HydrophobicContact CG-CG2 4.44Å; L337-Q403 WeakPolarHBondContact CB-O 3.27Å; L337-Q403 PolarHBondContact N-O 3.02Å; L337-Q403 VanDerWaalsContact N-O 3.07Å
338	N	89.1	Confident	91.9	Very high	106 Å²	106	43.2 Å²	43.2	57%	0.567	22%	0.223	S	C	*	.	G	3₁₀ helix	trans	-73.5	-26.4	178.3	-63.7	-22.9	0	0	0	112.5	G335 L336 L407	G335-N338 PolarHBondContact O-N 3.11Å; L336-N338 PolarHBondContact O-N 3.45Å; N338-L407 HydrophobicContact CB-CD1 3.68Å; N338-L407 HydrophobicContact CB-CD2 4.38Å; N338-L407 HydrophobicContact CB-CG 4.21Å
339	F	84.5	Confident	92.1	Very high	70 Å²	70	43.3 Å²	43.3	31%	0.307	23%	0.226	S	C	.	.	T	Hydrogen-bonded Turn	trans	-95.7	-39.7	-176.8	-69.6	-41.1	0	0	0	113.7	L336 L337 L407 F414	L336-F339 PolarHBondContact O-N 3.31Å; L336-F339 VanDerWaalsContact O-N 3.12Å; L337-F339 VanDerWaalsContact C-N 3.32Å; L337-F339 PolarHBondContact O-N 3.06Å; F339-L407 HydrophobicContact CD1-CD1 3.66Å; F339-L407 HydrophobicContact CD1-CD2 4.4Å; F339-L407 HydrophobicContact CD2-CD1 4.01Å; F339-L407 HydrophobicContact CD2-CD2 3.18Å; F339-L407 HydrophobicContact CD2-CG 4.06Å; F339-L407 HydrophobicContact CE1-CD1 3.13Å; F339-L407 HydrophobicContact CE1-CD2 4.25Å; F339-L407 HydrophobicContact CE1-CG 4.09Å; F339-L407 HydrophobicContact CE2-CB 3.78Å; F339-L407 HydrophobicContact CE2-CD1 3.57Å; F339-L407 HydrophobicContact CE2-CD2 3.02Å; F339-L407 HydrophobicContact CE2-CG 3.55Å; F339-L407 HydrophobicContact CG-CD1 4.06Å; F339-L407 HydrophobicContact CG-CD2 3.91Å; F339-L407 HydrophobicContact CZ-CB 3.66Å; F339-L407 HydrophobicContact CZ-CD1 3.06Å; F339-L407 HydrophobicContact CZ-CD2 3.58Å; F339-L407 HydrophobicContact CZ-CG 3.52Å; F339-F414 AromaticContact CD1-CD1 3.74Å; F339-F414 HydrophobicContact CD1-CD1 3.74Å; F339-F414 AromaticContact CD1-CE1 3.74Å; F339-F414 HydrophobicContact CD1-CE1 3.74Å; F339-F414 HydrophobicContact CD2-CD1 4.46Å; F339-F414 HydrophobicContact CD2-CE1 4.23Å; F339-F414 AromaticContact CE1-CD1 3.65Å; F339-F414 HydrophobicContact CE1-CD1 3.65Å; F339-F414 AromaticContact CE1-CE1 3.14Å; F339-F414 HydrophobicContact CE1-CE1 3.14Å; F339-F414 AromaticContact CE1-CZ 3.78Å; F339-F414 HydrophobicContact CE1-CZ 3.78Å; F339-F414 HydrophobicContact CE2-CD1 4.34Å; F339-F414 AromaticContact CE2-CE1 3.68Å; F339-F414 HydrophobicContact CE2-CE1 3.68Å; F339-F414 HydrophobicContact CG-CD1 4.18Å; F339-F414 HydrophobicContact CG-CE1 4.26Å; F339-F414 AromaticContact CZ-CD1 3.99Å; F339-F414 HydrophobicContact CZ-CD1 3.99Å; F339-F414 AromaticContact CZ-CE1 3.13Å; F339-F414 HydrophobicContact CZ-CE1 3.13Å; F339-F414 AromaticContact CZ-CZ 3.79Å; F339-F414 HydrophobicContact CZ-CZ 3.79Å
340	M	89.8	Confident	92.3	Very high	2 Å²	2	42 Å²	42	1%	0.01	22%	0.217	C	C	.	.			trans	-139.6	66.4	-172.4	56.7	167.5	-173.6	0	0	112.4	R324 L336 S342 M343 T344	R324-M340 PolarHBondContact NH1-SD 2.96Å; L336-M340 HydrophobicContact CB-CE 3.75Å; L336-M340 HydrophobicContact CB-CG 4.43Å; L336-M340 HydrophobicContact CD1-CE 3.61Å; L336-M340 HydrophobicContact CD2-CE 3.85Å; L336-M340 HydrophobicContact CG-CE 3.92Å; L336-M340 WeakPolarHBondContact O-CG 3.1Å; L336-M340 PolarHBondContact O-N 3.45Å; M340-S342 VanDerWaalsContact C-N 3.3Å; M340-S342 PolarHBondContact O-N 3.35Å; M340-M343 HydrophobicContact CB-CB 4.02Å; M340-M343 HydrophobicContact CB-CG 4.29Å; M340-M343 HydrophobicContact CE-CB 4.29Å; M340-M343 HydrophobicContact CG-CB 3.91Å; M340-M343 WeakPolarHBondContact O-CB 3.28Å; M340-M343 PolarHBondContact O-N 3Å; M340-M343 HydrophobicContact SD-CB 3.48Å; M340-M343 WeakPolarHBondContact SD-CB 3.47Å; M340-M343 HydrophobicContact SD-CG 3.82Å; M340-T344 WeakPolarHBondContact O-CG2 3.49Å; M340-T344 PolarHBondContact O-N 3.15Å
341	P	90.8	Very high	92.4	Very high	78 Å²	78	42 Å²	42	51%	0.506	22%	0.218	S	C	.	.	H	α-helix	trans	-59	-38.2	-172.1	23.4	-34.3	0	0	0	113.1	M343 T344 L345	P341-M343 VanDerWaalsContact C-N 3.34Å; P341-M343 PolarHBondContact O-N 3.11Å; P341-T344 PolarHBondContact O-N 2.97Å; P341-T344 VanDerWaalsContact O-N 3.1Å; P341-T344 PolarHBondContact O-OG1 3.2Å; P341-L345 PolarHBondContact O-N 3.44Å
342	S	92.3	Very high	92.7	Very high	50 Å²	50	38.2 Å²	38.2	35%	0.35	20%	0.2	S	C	.	.	H	α-helix	trans	-62.4	-37.4	175.5	42.3	0	0	0	0	112.9	M340 T344 Y422	M340-S342 VanDerWaalsContact C-N 3.3Å; M340-S342 PolarHBondContact O-N 3.35Å; S342-T344 VanDerWaalsContact C-N 3.34Å; S342-Y422 WeakPolarHBondContact CB-OH 3.11Å; S342-Y422 PolarHBondContact OG-OH 3.35Å
343	M	93.6	Very high	92.8	Very high	0 Å²	0	35.9 Å²	35.9	0%	0	19%	0.187	C	C	.	.	H	α-helix	trans	-71.5	-31.3	173.1	-73.3	-63.4	-175.8	0	0	112.1	V320 M340 P341 L345 W346 W347 E421 Y422	V320-M343 HydrophobicContact CG1-CE 4.42Å; M340-M343 HydrophobicContact CB-CB 4.02Å; M340-M343 HydrophobicContact CB-CG 4.29Å; M340-M343 HydrophobicContact CE-CB 4.29Å; M340-M343 HydrophobicContact CG-CB 3.91Å; M340-M343 WeakPolarHBondContact O-CB 3.28Å; M340-M343 PolarHBondContact O-N 3Å; M340-M343 HydrophobicContact SD-CB 3.48Å; M340-M343 WeakPolarHBondContact SD-CB 3.47Å; M340-M343 HydrophobicContact SD-CG 3.82Å; P341-M343 VanDerWaalsContact C-N 3.34Å; P341-M343 PolarHBondContact O-N 3.11Å; M343-L345 VanDerWaalsContact C-N 3.25Å; M343-L345 PolarHBondContact O-N 3.17Å; M343-W346 WeakPolarHBondContact O-CB 3.41Å; M343-W346 PolarHBondContact O-N 3.46Å; M343-W346 VanDerWaalsContact O-N 3.11Å; M343-W347 PolarHBondContact O-N 3.2Å; M343-E421 HydrophobicContact CE-CB 3.35Å; M343-E421 HydrophobicContact CE-CG 4.4Å; M343-E421 WeakPolarHBondContact CE-OE2 3.26Å; M343-Y422 HydrophobicContact CE-CD1 3.76Å; M343-Y422 HydrophobicContact CE-CD2 4.29Å; M343-Y422 HydrophobicContact CE-CE1 3.49Å; M343-Y422 VanDerWaalsContact CE-CE1 3.49Å; M343-Y422 HydrophobicContact CE-CE2 4.03Å; M343-Y422 HydrophobicContact CE-CG 4.16Å; M343-Y422 HydrophobicContact CG-CE1 3.93Å; M343-Y422 HydrophobicContact SD-CD1 3.92Å; M343-Y422 HydrophobicContact SD-CE1 3.52Å; M343-Y422 VanDerWaalsContact SD-CE1 3.52Å
344	T	94.3	Very high	93.1	Very high	9 Å²	9	36 Å²	36	6%	0.055	19%	0.189	C	C	.	.	H	α-helix	trans	-68	-27.8	178.4	73.8	0	0	0	0	112.9	L337 M340 P341 S342 W346 W347 F348 Q403	L337-T344 HydrophobicContact CB-CG2 4.01Å; L337-T344 HydrophobicContact CG-CG2 4.44Å; M340-T344 WeakPolarHBondContact O-CG2 3.49Å; M340-T344 PolarHBondContact O-N 3.15Å; P341-T344 PolarHBondContact O-N 2.97Å; P341-T344 VanDerWaalsContact O-N 3.1Å; P341-T344 PolarHBondContact O-OG1 3.2Å; S342-T344 VanDerWaalsContact C-N 3.34Å; T344-W346 VanDerWaalsContact C-N 3.34Å; T344-W347 WeakPolarHBondContact O-CB 3.46Å; T344-W347 PolarHBondContact O-N 3.07Å; T344-F348 PolarHBondContact O-N 3.2Å; T344-Q403 HydrophobicContact CG2-CG 4.48Å
345	L	94.6	Very high	93.3	Very high	97 Å²	97	35.1 Å²	35.1	51%	0.508	19%	0.186	S	C	.	.	H	α-helix	trans	-62.5	-42	170.4	-179	135.5	0	0	0	110.9	P341 M343 F348 L349	P341-L345 PolarHBondContact O-N 3.44Å; M343-L345 VanDerWaalsContact C-N 3.25Å; M343-L345 PolarHBondContact O-N 3.17Å; L345-F348 WeakPolarHBondContact O-CB 3.46Å; L345-F348 PolarHBondContact O-N 3.07Å; L345-L349 HydrophobicContact CD2-CD1 3.63Å; L345-L349 HydrophobicContact CD2-CG 4.35Å; L345-L349 HydrophobicContact CG-CD1 4.38Å; L345-L349 WeakPolarHBondContact O-CB 3.4Å; L345-L349 WeakPolarHBondContact O-CG 3.33Å; L345-L349 PolarHBondContact O-N 3.38Å
346	W	95.3	Very high	93.5	Very high	34 Å²	34	35.6 Å²	35.6	13%	0.129	19%	0.19	C	C	.	.	H	α-helix	trans	-67.4	-36.7	175.2	-64.9	107.5	0	0	0	113	L317 M343 T344 F348 L349 L350 Y422 M425 L426 W429	L317-W346 HydrophobicContact CD2-CB 4.23Å; M343-W346 WeakPolarHBondContact O-CB 3.41Å; M343-W346 PolarHBondContact O-N 3.46Å; M343-W346 VanDerWaalsContact O-N 3.11Å; T344-W346 VanDerWaalsContact C-N 3.34Å; W346-F348 VanDerWaalsContact C-N 3.33Å; W346-L349 HydrophobicContact CE3-CD1 3.96Å; W346-L349 HydrophobicContact CZ3-CD1 4Å; W346-L349 PolarHBondContact O-N 3.43Å; W346-L350 PolarHBondContact O-N 3.34Å; W346-Y422 AromaticContact CD1-CD1 3.81Å; W346-Y422 AromaticContact NE1-CD1 3.45Å; W346-M425 HydrophobicContact CB-CB 4.2Å; W346-M425 HydrophobicContact CB-CG 4.15Å; W346-M425 HydrophobicContact CD2-CB 3.69Å; W346-M425 HydrophobicContact CD2-CG 4.5Å; W346-M425 HydrophobicContact CE3-CB 3.89Å; W346-M425 HydrophobicContact CG-CB 3.83Å; W346-M425 HydrophobicContact CG-CG 4.12Å; W346-L426 HydrophobicContact CH2-CB 4.09Å; W346-L426 HydrophobicContact CH2-CD1 3.68Å; W346-L426 HydrophobicContact CZ2-CD1 4.4Å; W346-W429 HydrophobicContact CE3-CB 4.44Å; W346-W429 HydrophobicContact CZ3-CB 3.96Å; W346-W429 HydrophobicContact CZ3-CD2 4.26Å; W346-W429 HydrophobicContact CZ3-CE3 4.4Å; W346-W429 HydrophobicContact CZ3-CG 4.11Å
347	W	95.7	Very high	93.6	Very high	1 Å²	1	36.6 Å²	36.6	0%	0.004	20%	0.199	C	C	.	.	H	α-helix	trans	-57.7	-46.9	169.7	-84.1	101.3	0	0	0	111.6	L270 L317 M343 T344 S351 L398 Y399 Q403	L270-W347 HydrophobicContact CD2-CH2 4.18Å; L317-W347 HydrophobicContact CB-CD2 3.98Å; L317-W347 HydrophobicContact CB-CE3 4.19Å; L317-W347 HydrophobicContact CB-CH2 3.79Å; L317-W347 HydrophobicContact CB-CZ2 3.56Å; L317-W347 HydrophobicContact CB-CZ3 4.08Å; L317-W347 HydrophobicContact CD1-CB 4.4Å; L317-W347 HydrophobicContact CD1-CD2 3.74Å; L317-W347 HydrophobicContact CD1-CE3 3.87Å; L317-W347 HydrophobicContact CD1-CG 3.95Å; L317-W347 HydrophobicContact CD1-CZ3 4.42Å; L317-W347 HydrophobicContact CD2-CD2 4.43Å; L317-W347 HydrophobicContact CD2-CG 4.31Å; L317-W347 HydrophobicContact CG-CD2 4.28Å; L317-W347 WeakPolarHBondContact O-CZ2 3.49Å; M343-W347 PolarHBondContact O-N 3.2Å; T344-W347 WeakPolarHBondContact O-CB 3.46Å; T344-W347 PolarHBondContact O-N 3.07Å; W347-S351 WeakPolarHBondContact O-CB 3.1Å; W347-S351 PolarHBondContact O-N 2.95Å; W347-S351 PolarHBondContact O-OG 3.44Å; W347-L398 HydrophobicContact CE3-CD2 3.68Å; W347-L398 HydrophobicContact CZ3-CD1 4.44Å; W347-L398 HydrophobicContact CZ3-CD2 3.49Å; W347-L398 VanDerWaalsContact CZ3-CD2 3.49Å; W347-L398 HydrophobicContact CZ3-CG 4.27Å; W347-Y399 HydrophobicContact CB-CD2 4.1Å; W347-Y399 HydrophobicContact CB-CE2 4.08Å; W347-Q403 HydrophobicContact CB-CG 4.22Å; W347-Q403 VanDerWaalsContact CD1-NE2 3.26Å; W347-Q403 HydrophobicContact CG-CG 4.41Å; W347-Q403 VanDerWaalsContact CG-NE2 3.29Å
348	F	95.9	Very high	93.4	Very high	106 Å²	106	38.5 Å²	38.5	47%	0.465	22%	0.215	S	C	.	.	H	α-helix	trans	-60.1	-52.3	177.8	178	-103.4	0	0	0	110.9	T344 L345 W346 L350 S351 S352 Y399	T344-F348 PolarHBondContact O-N 3.2Å; L345-F348 WeakPolarHBondContact O-CB 3.46Å; L345-F348 PolarHBondContact O-N 3.07Å; W346-F348 VanDerWaalsContact C-N 3.33Å; F348-L350 PolarHBondContact O-N 3.33Å; F348-S351 WeakPolarHBondContact CA-OG 3.06Å; F348-S351 PolarHBondContact O-N 3.04Å; F348-S351 PolarHBondContact O-OG 3.04Å; F348-S352 WeakPolarHBondContact O-CB 3.28Å; F348-S352 PolarHBondContact O-N 3.36Å; F348-S352 PolarHBondContact O-OG 2.97Å; F348-Y399 HydrophobicContact CB-CD2 4.46Å; F348-Y399 HydrophobicContact CB-CE2 3.68Å; F348-Y399 HydrophobicContact CD2-CE1 4.41Å; F348-Y399 HydrophobicContact CD2-CE2 4.38Å
349	L	96	Very high	93.3	Very high	37 Å²	37	38.2 Å²	38.2	19%	0.194	22%	0.219	C	C	.	.	H	α-helix	trans	-60.1	-39.2	-177.3	-74.2	179.1	0	0	0	114.3	L345 W346 S352 A353 W429	L345-L349 HydrophobicContact CD2-CD1 3.63Å; L345-L349 HydrophobicContact CD2-CG 4.35Å; L345-L349 HydrophobicContact CG-CD1 4.38Å; L345-L349 WeakPolarHBondContact O-CB 3.4Å; L345-L349 WeakPolarHBondContact O-CG 3.33Å; L345-L349 PolarHBondContact O-N 3.38Å; W346-L349 HydrophobicContact CE3-CD1 3.96Å; W346-L349 HydrophobicContact CZ3-CD1 4Å; W346-L349 PolarHBondContact O-N 3.43Å; L349-S352 PolarHBondContact O-OG 3.48Å; L349-A353 PolarHBondContact O-N 3.16Å; L349-W429 HydrophobicContact CD1-CD2 4.4Å; L349-W429 HydrophobicContact CD1-CZ2 4.21Å; L349-W429 HydrophobicContact CD2-CZ2 4.04Å
350	L	96.3	Very high	93.7	Very high	0 Å²	0	35.3 Å²	35.3	0%	0	21%	0.207	C	C	.	.	H	α-helix	trans	-80.9	-31.7	175.6	-73.6	-175.6	0	0	0	112.8	G313 L314 L317 W346 F348 S352 A353 N354 M425 W429	G313-L350 VanDerWaalsContact C-CD1 3.49Å; L314-L350 HydrophobicContact CD2-CB 3.91Å; L314-L350 HydrophobicContact CG-CB 4.46Å; L317-L350 HydrophobicContact CD1-CB 4.23Å; L317-L350 HydrophobicContact CD1-CD1 3.76Å; L317-L350 HydrophobicContact CD1-CG 4.47Å; L317-L350 HydrophobicContact CG-CD1 4.37Å; W346-L350 PolarHBondContact O-N 3.34Å; F348-L350 PolarHBondContact O-N 3.33Å; L350-S352 VanDerWaalsContact C-N 3.35Å; L350-A353 PolarHBondContact O-N 3.28Å; L350-N354 PolarHBondContact O-N 3.48Å; L350-M425 HydrophobicContact CD1-CE 3.11Å; L350-M425 HydrophobicContact CG-CE 4.2Å; L350-W429 HydrophobicContact CD2-CB 4.44Å
351	S	96.2	Very high	93.9	Very high	3 Å²	3	35.3 Å²	35.3	2%	0.021	21%	0.207	C	C	.	.	H	α-helix	trans	-66	-38.4	173.7	70.3	0	0	0	0	111.7	W347 F348 N354 M355	W347-S351 WeakPolarHBondContact O-CB 3.1Å; W347-S351 PolarHBondContact O-N 2.95Å; W347-S351 PolarHBondContact O-OG 3.44Å; F348-S351 WeakPolarHBondContact CA-OG 3.06Å; F348-S351 PolarHBondContact O-N 3.04Å; F348-S351 PolarHBondContact O-OG 3.04Å; S351-N354 WeakPolarHBondContact O-CB 3.24Å; S351-N354 PolarHBondContact O-N 3.31Å; S351-M355 WeakPolarHBondContact O-CG 3.48Å; S351-M355 PolarHBondContact O-N 2.91Å
352	S	95.5	Very high	94.1	Very high	24 Å²	24	31.6 Å²	31.6	17%	0.168	18%	0.183	C	C	.	.	H	α-helix	trans	-68.5	-36.3	175	66.2	0	0	0	0	111.9	F348 L349 L350 N354 M355 A356 A357	F348-S352 WeakPolarHBondContact O-CB 3.28Å; F348-S352 PolarHBondContact O-N 3.36Å; F348-S352 PolarHBondContact O-OG 2.97Å; L349-S352 PolarHBondContact O-OG 3.48Å; L350-S352 VanDerWaalsContact C-N 3.35Å; S352-N354 VanDerWaalsContact C-N 3.32Å; S352-N354 PolarHBondContact O-N 3.27Å; S352-M355 PolarHBondContact O-N 3.09Å; S352-A356 PolarHBondContact O-N 2.96Å; S352-A357 WeakPolarHBondContact O-CB 3.28Å; S352-A357 PolarHBondContact O-N 2.98Å
353	A	95.4	Very high	94.2	Very high	0 Å²	0	31.8 Å²	31.8	0%	0	18%	0.18	C	C	.	.	H	α-helix	trans	-61.7	-40.1	169.8	0	0	0	0	0	111.8	L349 L350 M355 A356 T360 N362 L432	L349-A353 PolarHBondContact O-N 3.16Å; L350-A353 PolarHBondContact O-N 3.28Å; A353-M355 VanDerWaalsContact C-N 3.3Å; A353-M355 PolarHBondContact O-N 3.32Å; A353-A356 WeakPolarHBondContact O-CA 3.21Å; A353-A356 PolarHBondContact O-N 3.15Å; A353-T360 HydrophobicContact CB-CG2 4.04Å; A353-N362 PolarHBondContact O-ND2 2.81Å; A353-L432 HydrophobicContact CB-CD1 4.12Å; A353-L432 HydrophobicContact CB-CD2 3.98Å
354	N	95.7	Very high	94.3	Very high	4 Å²	4	33.2 Å²	33.2	2%	0.021	19%	0.187	C	C	.	.	H	α-helix	trans	-68.7	-26.6	177.1	-156.1	38	0	0	0	113.3	H281 L314 L350 S351 S352 A356 T395	H281-N354 PolarHBondContact CE1-O 2.83Å; H281-N354 VanDerWaalsContact CE1-O 3.31Å; H281-N354 PolarHBondContact NE2-OD1 3.01Å; H281-N354 VanDerWaalsContact NE2-OD1 3.16Å; L314-N354 HydrophobicContact CD1-CB 4.1Å; L350-N354 PolarHBondContact O-N 3.48Å; S351-N354 WeakPolarHBondContact O-CB 3.24Å; S351-N354 PolarHBondContact O-N 3.31Å; S352-N354 VanDerWaalsContact C-N 3.32Å; S352-N354 PolarHBondContact O-N 3.27Å; N354-A356 PolarHBondContact O-N 2.67Å; N354-T395 HydrophobicContact CB-CG2 3.86Å; N354-T395 VanDerWaalsContact ND2-CG2 3.3Å; N354-T395 WeakPolarHBondContact ND2-CG2 3.4Å
355	M	93.8	Very high	94.3	Very high	45 Å²	45	32.8 Å²	32.8	22%	0.222	19%	0.185	C	C	.	.	T	Hydrogen-bonded Turn	trans	-77.9	0.4	169.3	-66.9	177.6	-152.8	0	0	113.7	S351 S352 A353 A357 T395 L396	S351-M355 WeakPolarHBondContact O-CG 3.48Å; S351-M355 PolarHBondContact O-N 2.91Å; S352-M355 PolarHBondContact O-N 3.09Å; A353-M355 VanDerWaalsContact C-N 3.3Å; A353-M355 PolarHBondContact O-N 3.32Å; M355-A357 PolarHBondContact O-N 3Å; M355-T395 VanDerWaalsContact CE-CB 3.42Å; M355-T395 WeakPolarHBondContact CE-OG1 3.5Å; M355-T395 HydrophobicContact CG-CG2 4.11Å; M355-T395 WeakPolarHBondContact CG-OG1 3.47Å; M355-L396 HydrophobicContact CE-CB 4.22Å; M355-L396 HydrophobicContact CE-CD2 3.51Å; M355-L396 HydrophobicContact CE-CG 3.48Å; M355-L396 VanDerWaalsContact CE-CG 3.48Å; M355-L396 HydrophobicContact SD-CD2 4.17Å; M355-L396 HydrophobicContact SD-CG 4.06Å
356	A	93.9	Very high	94.4	Very high	10 Å²	10	29.2 Å²	29.2	8%	0.083	17%	0.165	C	C	.	.	T	Hydrogen-bonded Turn	trans	55.6	47.6	-172.2	0	0	0	0	0	113	S352 A353 N354 N362 L363 E366	S352-A356 PolarHBondContact O-N 2.96Å; A353-A356 WeakPolarHBondContact O-CA 3.21Å; A353-A356 PolarHBondContact O-N 3.15Å; N354-A356 PolarHBondContact O-N 2.67Å; A356-N362 HydrophobicContact CB-CB 4.14Å; A356-L363 HydrophobicContact CB-CB 4.18Å; A356-L363 WeakPolarHBondContact O-CB 3.35Å; A356-L363 WeakPolarHBondContact O-CD1 3.46Å; A356-E366 HydrophobicContact CB-CG 4.37Å; A356-E366 WeakPolarHBondContact CB-OE2 3.2Å
357	A	93	Very high	94.4	Very high	29 Å²	29	31.2 Å²	31.2	24%	0.24	18%	0.178	C	C	.	.			trans	-71.3	149	173	0	0	0	0	0	112	S352 M355 T360	S352-A357 WeakPolarHBondContact O-CB 3.28Å; S352-A357 PolarHBondContact O-N 2.98Å; M355-A357 PolarHBondContact O-N 3Å; A357-T360 VanDerWaalsContact O-CB 3.27Å; A357-T360 WeakPolarHBondContact O-CB 3.26Å; A357-T360 WeakPolarHBondContact O-CG2 3.47Å; A357-T360 PolarHBondContact O-N 2.93Å; A357-T360 VanDerWaalsContact O-N 3.16Å; A357-T360 PolarHBondContact O-OG1 3Å
358	P	89.2	Confident	94.4	Very high	103 Å²	103	33.7 Å²	33.7	67%	0.669	19%	0.188	S	C	*	.	T	Hydrogen-bonded Turn	trans	-70.4	144.3	171	29.1	-33.5	0	0	0	110.7	L363	P358-L363 HydrophobicContact CB-CD1 4.16Å
359	P	86.7	Confident	94.4	Very high	100 Å²	100	28.7 Å²	28.7	65%	0.649	17%	0.166	S	C	*	.	T	Hydrogen-bonded Turn	cis	-98.5	87.3	-5.6	35.8	-27.3	0	0	0	110.6	I436	P359-I436 WeakPolarHBondContact O-CD1 2.92Å
360	T	93.4	Very high	94.4	Very high	10 Å²	10	29.7 Å²	29.7	6%	0.061	17%	0.171	C	C	.	.			trans	-116.2	150.2	179.1	63.8	0	0	0	0	112.3	A353 A357 N362 L363 L432	A353-T360 HydrophobicContact CB-CG2 4.04Å; A357-T360 VanDerWaalsContact O-CB 3.27Å; A357-T360 WeakPolarHBondContact O-CB 3.26Å; A357-T360 WeakPolarHBondContact O-CG2 3.47Å; A357-T360 PolarHBondContact O-N 2.93Å; A357-T360 VanDerWaalsContact O-N 3.16Å; A357-T360 PolarHBondContact O-OG1 3Å; T360-N362 PolarHBondContact O-N 2.6Å; T360-L363 PolarHBondContact O-N 3.18Å; T360-L432 HydrophobicContact CG2-CD2 3.81Å
361	L	94.2	Very high	94.4	Very high	1 Å²	1	34 Å²	34	1%	0.005	19%	0.194	C	C	.	.	H	α-helix	trans	-63.6	-27.6	177.2	-163.6	84.6	0	0	0	111.4	I305 A306 L364 G365 L435 I436 F442	I305-L361 HydrophobicContact CB-CD2 4.32Å; I305-L361 HydrophobicContact CG2-CD2 4.11Å; A306-L361 HydrophobicContact CB-CB 3.7Å; A306-L361 HydrophobicContact CB-CD2 3.6Å; A306-L361 HydrophobicContact CB-CG 3.88Å; L361-L364 PolarHBondContact O-N 3.42Å; L361-G365 PolarHBondContact O-N 3.14Å; L361-L435 HydrophobicContact CD1-CB 4.22Å; L361-I436 HydrophobicContact CB-CG1 4Å; L361-I436 HydrophobicContact CD1-CG1 3.99Å; L361-F442 HydrophobicContact CD1-CD2 4.36Å
362	N	95.4	Very high	94.4	Very high	1 Å²	1	33.9 Å²	33.9	1%	0.005	19%	0.193	C	C	.	.	H	α-helix	trans	-59.7	-47.3	174.9	-79	-24.1	0	0	0	111	A306 H307 A353 A356 T360 L364 G365 E366	A306-N362 HydrophobicContact CB-CB 4.38Å; A306-N362 WeakPolarHBondContact CB-OD1 2.88Å; H307-N362 PolarHBondContact N-OD1 3.37Å; A353-N362 PolarHBondContact O-ND2 2.81Å; A356-N362 HydrophobicContact CB-CB 4.14Å; T360-N362 PolarHBondContact O-N 2.6Å; N362-L364 VanDerWaalsContact C-N 3.29Å; N362-L364 PolarHBondContact O-N 3.5Å; N362-G365 PolarHBondContact O-N 2.74Å; N362-E366 WeakPolarHBondContact O-CG 3.03Å; N362-E366 PolarHBondContact O-N 3.38Å
363	L	94.8	Very high	94.5	Very high	53 Å²	53	32.7 Å²	32.7	28%	0.277	19%	0.185	S	C	.	.	H	α-helix	trans	-58.6	-42.5	177.3	178.2	141.1	0	0	0	112	A356 P358 T360 E366 I367	A356-L363 HydrophobicContact CB-CB 4.18Å; A356-L363 WeakPolarHBondContact O-CB 3.35Å; A356-L363 WeakPolarHBondContact O-CD1 3.46Å; P358-L363 HydrophobicContact CB-CD1 4.16Å; T360-L363 PolarHBondContact O-N 3.18Å; L363-E366 PolarHBondContact O-N 3.49Å; L363-I367 HydrophobicContact CD2-CD1 3.42Å; L363-I367 VanDerWaalsContact CD2-CD1 3.42Å; L363-I367 HydrophobicContact CD2-CG1 4.45Å; L363-I367 HydrophobicContact CG-CD1 3.84Å; L363-I367 HydrophobicContact CG-CG1 4.44Å; L363-I367 VanDerWaalsContact O-CG1 3.28Å; L363-I367 WeakPolarHBondContact O-CG1 3.14Å; L363-I367 PolarHBondContact O-N 2.85Å
364	L	94.7	Very high	94.5	Very high	30 Å²	30	33.9 Å²	33.9	16%	0.157	19%	0.192	C	C	.	.	H	α-helix	trans	-60	-50.7	177.3	-166.3	154.6	0	0	0	110.2	T302 L361 N362 E366 I367 Y368 M443	T302-L364 HydrophobicContact CG2-CD2 4.22Å; L361-L364 PolarHBondContact O-N 3.42Å; N362-L364 VanDerWaalsContact C-N 3.29Å; N362-L364 PolarHBondContact O-N 3.5Å; L364-E366 PolarHBondContact O-N 3.2Å; L364-I367 PolarHBondContact O-N 3.43Å; L364-Y368 HydrophobicContact CD2-CD2 3.98Å; L364-Y368 HydrophobicContact CD2-CE2 3.83Å; L364-Y368 HydrophobicContact CG-CE2 4.22Å; L364-Y368 WeakPolarHBondContact O-CD2 3.22Å; L364-Y368 PolarHBondContact O-N 2.68Å; L364-M443 HydrophobicContact CD2-CE 4.28Å; L364-M443 HydrophobicContact CD2-CG 4.24Å; L364-M443 HydrophobicContact CD2-SD 3.24Å; L364-M443 WeakPolarHBondContact CD2-SD 3.39Å
365	G	95.1	Very high	94.5	Very high	0 Å²	0	37.6 Å²	37.6	0%	0	22%	0.219	C	C	.	.	H	α-helix	trans	-60.9	-43.6	178.1	0	0	0	0	0	113.5	T302 L361 N362 I367 Y368 L369	T302-G365 WeakPolarHBondContact OG1-CA 3.4Å; L361-G365 PolarHBondContact O-N 3.14Å; N362-G365 PolarHBondContact O-N 2.74Å; G365-I367 PolarHBondContact O-N 3.27Å; G365-Y368 PolarHBondContact O-N 2.83Å; G365-L369 VanDerWaalsContact O-CG 3.28Å; G365-L369 WeakPolarHBondContact O-CG 3.23Å; G365-L369 PolarHBondContact O-N 2.66Å
366	E	95.5	Very high	94.5	Very high	22 Å²	22	40.1 Å²	40.1	10%	0.103	23%	0.226	C	C	.	.	H	α-helix	trans	-64.7	-40.2	-179.7	-70	-170.4	177.7	0	0	112.5	H281 L303 A356 N362 L363 L364 Y368 L369 L370	H281-E366 IonicContact CE1-OE1 2.79Å; H281-E366 PolarHBondContact CE1-OE1 3.01Å; H281-E366 IonicContact ND1-OE1 2.66Å; H281-E366 PolarHBondContact ND1-OE1 2.94Å; L303-E366 HydrophobicContact CD1-CB 4.4Å; L303-E366 HydrophobicContact CD1-CG 3.36Å; A356-E366 HydrophobicContact CB-CG 4.37Å; A356-E366 WeakPolarHBondContact CB-OE2 3.2Å; N362-E366 WeakPolarHBondContact O-CG 3.03Å; N362-E366 PolarHBondContact O-N 3.38Å; L363-E366 PolarHBondContact O-N 3.49Å; L364-E366 PolarHBondContact O-N 3.2Å; E366-Y368 VanDerWaalsContact C-N 3.33Å; E366-Y368 PolarHBondContact O-N 3.24Å; E366-L369 PolarHBondContact O-N 3.5Å; E366-L370 WeakPolarHBondContact O-CB 3.26Å; E366-L370 VanDerWaalsContact O-CG 3.23Å; E366-L370 WeakPolarHBondContact O-CG 3.32Å; E366-L370 PolarHBondContact O-N 2.57Å
367	I	95.4	Very high	94.5	Very high	77 Å²	77	41.1 Å²	41.1	40%	0.395	23%	0.232	S	C	.	.	H	α-helix	trans	-61.1	-43	176.9	-69.9	169.6	0	0	0	111.1	L363 L364 G365 L370 N371	L363-I367 HydrophobicContact CD2-CD1 3.42Å; L363-I367 VanDerWaalsContact CD2-CD1 3.42Å; L363-I367 HydrophobicContact CD2-CG1 4.45Å; L363-I367 HydrophobicContact CG-CD1 3.84Å; L363-I367 HydrophobicContact CG-CG1 4.44Å; L363-I367 VanDerWaalsContact O-CG1 3.28Å; L363-I367 WeakPolarHBondContact O-CG1 3.14Å; L363-I367 PolarHBondContact O-N 2.85Å; L364-I367 PolarHBondContact O-N 3.43Å; G365-I367 PolarHBondContact O-N 3.27Å; I367-L370 PolarHBondContact O-N 2.99Å; I367-N371 VanDerWaalsContact O-CG 3.3Å; I367-N371 PolarHBondContact O-N 3.05Å; I367-N371 VanDerWaalsContact O-N 3.08Å; I367-N371 PolarHBondContact O-ND2 2.82Å
368	Y	95.4	Very high	94.5	Very high	53 Å²	53	49.8 Å²	49.8	21%	0.208	26%	0.259	C	S	.	.	H	α-helix	trans	-65.1	-41.6	178.2	-83.7	-107.8	0	0	0	112	W295 L364 G365 E366 N371 S372 M443	W295-Y368 HydrophobicContact CB-CD1 4.31Å; W295-Y368 HydrophobicContact CD2-CD1 4.08Å; W295-Y368 HydrophobicContact CD2-CE1 4.05Å; W295-Y368 AromaticContact CE3-CD1 3.15Å; W295-Y368 HydrophobicContact CE3-CD1 3.15Å; W295-Y368 AromaticContact CE3-CE1 2.98Å; W295-Y368 HydrophobicContact CE3-CE1 2.98Å; W295-Y368 HydrophobicContact CE3-CG 4.04Å; W295-Y368 AromaticContact CE3-CZ 3.83Å; W295-Y368 HydrophobicContact CH2-CE1 4.12Å; W295-Y368 AromaticContact CZ3-CD1 3.72Å; W295-Y368 HydrophobicContact CZ3-CD1 3.72Å; W295-Y368 AromaticContact CZ3-CE1 3.02Å; W295-Y368 HydrophobicContact CZ3-CE1 3.02Å; W295-Y368 HydrophobicContact CZ3-CE2 4.33Å; W295-Y368 AromaticContact CZ3-CZ 3.43Å; W295-Y368 VanDerWaalsContact CZ3-CZ 3.43Å; L364-Y368 HydrophobicContact CD2-CD2 3.98Å; L364-Y368 HydrophobicContact CD2-CE2 3.83Å; L364-Y368 HydrophobicContact CG-CE2 4.22Å; L364-Y368 WeakPolarHBondContact O-CD2 3.22Å; L364-Y368 PolarHBondContact O-N 2.68Å; G365-Y368 PolarHBondContact O-N 2.83Å; E366-Y368 VanDerWaalsContact C-N 3.33Å; E366-Y368 PolarHBondContact O-N 3.24Å; Y368-N371 PolarHBondContact O-N 3.43Å; Y368-S372 PolarHBondContact O-N 3.31Å; Y368-S372 PolarHBondContact O-OG 2.92Å; Y368-M443 HydrophobicContact CD1-CE 3.32Å; Y368-M443 HydrophobicContact CD2-CE 4.09Å; Y368-M443 HydrophobicContact CE1-CE 2.91Å; Y368-M443 HydrophobicContact CE1-SD 4.42Å; Y368-M443 HydrophobicContact CE2-CE 3.73Å; Y368-M443 HydrophobicContact CE2-SD 4.37Å; Y368-M443 HydrophobicContact CG-CE 3.91Å
369	L	96.8	Very high	94.8	Very high	0 Å²	0	51.4 Å²	51.4	0%	0	26%	0.261	C	S	.	.	H	α-helix	trans	-68	-39.8	177.5	-68.6	170.8	0	0	0	112.3	I284 V285 L303 G365 E366 S372 I373	I284-L369 HydrophobicContact CG2-CB 3.99Å; I284-L369 HydrophobicContact CG2-CD1 3.96Å; V285-L369 HydrophobicContact CG2-CD1 4.36Å; L303-L369 HydrophobicContact CB-CD1 3.99Å; L303-L369 HydrophobicContact CD1-CD1 4.32Å; L303-L369 HydrophobicContact CD2-CD1 4.06Å; L303-L369 HydrophobicContact CG-CD1 4.34Å; G365-L369 VanDerWaalsContact O-CG 3.28Å; G365-L369 WeakPolarHBondContact O-CG 3.23Å; G365-L369 PolarHBondContact O-N 2.66Å; E366-L369 PolarHBondContact O-N 3.5Å; L369-S372 PolarHBondContact O-N 2.7Å; L369-S372 PolarHBondContact O-OG 3.17Å; L369-I373 WeakPolarHBondContact O-CB 3.27Å; L369-I373 VanDerWaalsContact O-CD1 3.32Å; L369-I373 WeakPolarHBondContact O-CD1 3.31Å; L369-I373 WeakPolarHBondContact O-CG1 3.47Å; L369-I373 PolarHBondContact O-N 3.44Å
370	L	96.6	Very high	95.1	Very high	58 Å²	58	46.9 Å²	46.9	30%	0.304	23%	0.231	S	C	.	.	H	α-helix	trans	-61.2	-47.4	175.3	-72.7	171.7	0	0	0	110.5	E366 I367 S372 I373 V374 L384	E366-L370 WeakPolarHBondContact O-CB 3.26Å; E366-L370 VanDerWaalsContact O-CG 3.23Å; E366-L370 WeakPolarHBondContact O-CG 3.32Å; E366-L370 PolarHBondContact O-N 2.57Å; I367-L370 PolarHBondContact O-N 2.99Å; L370-S372 PolarHBondContact O-N 2.99Å; L370-I373 PolarHBondContact O-N 2.63Å; L370-V374 WeakPolarHBondContact O-CB 3.28Å; L370-V374 WeakPolarHBondContact O-CG2 3.39Å; L370-V374 PolarHBondContact O-N 3.08Å; L370-L384 HydrophobicContact CD2-CB 3.79Å; L370-L384 HydrophobicContact CD2-CD1 3.91Å; L370-L384 HydrophobicContact CD2-CD2 3.92Å; L370-L384 HydrophobicContact CD2-CG 4.08Å
371	N	96.1	Very high	95.2	Very high	90 Å²	90	50.6 Å²	50.6	48%	0.481	25%	0.249	S	C	.	.	H	α-helix	trans	-62.7	-41.7	179.1	-71.4	-18	0	0	0	112.3	I367 Y368 S375	I367-N371 VanDerWaalsContact O-CG 3.3Å; I367-N371 PolarHBondContact O-N 3.05Å; I367-N371 VanDerWaalsContact O-N 3.08Å; I367-N371 PolarHBondContact O-ND2 2.82Å; Y368-N371 PolarHBondContact O-N 3.43Å; N371-S375 WeakPolarHBondContact O-CB 3.38Å; N371-S375 PolarHBondContact O-N 2.96Å
372	S	96.4	Very high	95.3	Very high	1 Å²	1	55.6 Å²	55.6	1%	0.007	27%	0.274	C	S	.	.	H	α-helix	trans	-65.1	-46.2	179.2	66.1	0	0	0	0	112.5	T293 G296 Y368 L369 L370 S375 W376	T293-S372 WeakPolarHBondContact OG1-CB 3.4Å; G296-S372 VanDerWaalsContact CA-CB 3.45Å; G296-S372 WeakPolarHBondContact CA-OG 3.4Å; Y368-S372 PolarHBondContact O-N 3.31Å; Y368-S372 PolarHBondContact O-OG 2.92Å; L369-S372 PolarHBondContact O-N 2.7Å; L369-S372 PolarHBondContact O-OG 3.17Å; L370-S372 PolarHBondContact O-N 2.99Å; S372-S375 PolarHBondContact O-N 3.22Å; S372-S375 PolarHBondContact O-OG 3.22Å; S372-W376 PolarHBondContact O-N 2.77Å; S372-W376 VanDerWaalsContact O-N 3.16Å
373	I	96.6	Very high	95.4	Very high	0 Å²	0	57.8 Å²	57.8	0%	0	29%	0.286	C	S	.	.	H	α-helix	trans	-70	-39.4	-176.3	-62	162.8	0	0	0	110.5	L254 I284 S287 T291 L369 L370 S375 W376 S377 S380 L384	L254-I373 HydrophobicContact CD1-CG2 3.99Å; L254-I373 HydrophobicContact CD2-CD1 4.48Å; L254-I373 HydrophobicContact CD2-CG2 4.45Å; I284-I373 HydrophobicContact CG2-CD1 4.24Å; S287-I373 VanDerWaalsContact OG-CD1 3.26Å; S287-I373 WeakPolarHBondContact OG-CD1 3.39Å; T291-I373 HydrophobicContact CG2-CG1 4.31Å; L369-I373 WeakPolarHBondContact O-CB 3.27Å; L369-I373 VanDerWaalsContact O-CD1 3.32Å; L369-I373 WeakPolarHBondContact O-CD1 3.31Å; L369-I373 WeakPolarHBondContact O-CG1 3.47Å; L369-I373 PolarHBondContact O-N 3.44Å; L370-I373 PolarHBondContact O-N 2.63Å; I373-S375 VanDerWaalsContact C-N 3.32Å; I373-S375 PolarHBondContact O-N 3.19Å; I373-W376 WeakPolarHBondContact O-CB 3.27Å; I373-W376 PolarHBondContact O-N 3.1Å; I373-W376 VanDerWaalsContact O-N 3.15Å; I373-S377 PolarHBondContact O-N 3.02Å; I373-S380 PolarHBondContact O-OG 2.8Å; I373-S380 VanDerWaalsContact O-OG 3.14Å; I373-L384 HydrophobicContact CB-CD1 3.92Å; I373-L384 HydrophobicContact CD1-CD2 3.95Å; I373-L384 HydrophobicContact CG2-CD1 3.77Å; I373-L384 HydrophobicContact CG2-CD2 4.26Å; I373-L384 HydrophobicContact CG2-CG 4.27Å
374	V	96.5	Very high	95.4	Very high	24 Å²	24	55.5 Å²	55.5	15%	0.145	27%	0.274	C	S	.	.	H	α-helix	trans	-62.5	-40.2	173.5	171.4	0	0	0	0	111.1	L370 W376 S377 W378 M381 L384	L370-V374 WeakPolarHBondContact O-CB 3.28Å; L370-V374 WeakPolarHBondContact O-CG2 3.39Å; L370-V374 PolarHBondContact O-N 3.08Å; V374-W376 PolarHBondContact O-N 2.88Å; V374-S377 CarbonylContact O-C 3.57Å; V374-S377 PolarHBondContact O-N 3.45Å; V374-W378 HydrophobicContact CG1-CE3 4.29Å; V374-W378 HydrophobicContact CG1-CZ3 4.27Å; V374-M381 HydrophobicContact CB-CE 4.19Å; V374-M381 HydrophobicContact CG1-CE 3.54Å; V374-M381 HydrophobicContact CG2-CE 3.48Å; V374-M381 VanDerWaalsContact CG2-CE 3.48Å; V374-M381 HydrophobicContact CG2-SD 3.74Å; V374-L384 HydrophobicContact CG2-CD1 3.79Å
375	S	94.9	Very high	95.5	Very high	83 Å²	83	56.9 Å²	56.9	58%	0.58	29%	0.286	S	S	*	.	H	α-helix	trans	-64.5	-27.2	176.4	77.9	0	0	0	0	113.4	N371 S372 I373	N371-S375 WeakPolarHBondContact O-CB 3.38Å; N371-S375 PolarHBondContact O-N 2.96Å; S372-S375 PolarHBondContact O-N 3.22Å; S372-S375 PolarHBondContact O-OG 3.22Å; I373-S375 VanDerWaalsContact C-N 3.32Å; I373-S375 PolarHBondContact O-N 3.19Å
376	W	93.8	Very high	95.6	Very high	97 Å²	97	61.5 Å²	61.5	37%	0.367	31%	0.307	S	S	.	.	H	α-helix	trans	-74	-45.1	177	178	79.1	0	0	0	112.2	F247 I250 T291 S372 I373 V374	F247-W376 HydrophobicContact CB-CH2 4.07Å; F247-W376 HydrophobicContact CB-CZ2 3.75Å; I250-W376 HydrophobicContact CB-CZ3 4.48Å; I250-W376 HydrophobicContact CD1-CD2 3.98Å; I250-W376 HydrophobicContact CD1-CE3 4.32Å; I250-W376 HydrophobicContact CD1-CG 4.43Å; I250-W376 HydrophobicContact CD1-CH2 4.47Å; I250-W376 HydrophobicContact CD1-CZ2 4.11Å; I250-W376 HydrophobicContact CG2-CE3 4.06Å; I250-W376 HydrophobicContact CG2-CH2 4.32Å; I250-W376 HydrophobicContact CG2-CZ3 3.82Å; T291-W376 HydrophobicContact CG2-CB 3.88Å; T291-W376 HydrophobicContact CG2-CG 4.2Å; S372-W376 PolarHBondContact O-N 2.77Å; S372-W376 VanDerWaalsContact O-N 3.16Å; I373-W376 WeakPolarHBondContact O-CB 3.27Å; I373-W376 PolarHBondContact O-N 3.1Å; I373-W376 VanDerWaalsContact O-N 3.15Å; V374-W376 PolarHBondContact O-N 2.88Å
377	S	93.6	Very high	95.6	Very high	32 Å²	32	60.8 Å²	60.8	22%	0.224	30%	0.304	C	S	.	.			trans	-156.1	137.5	169.6	66.8	0	0	0	0	112.6	I373 V374 I379 S380	I373-S377 PolarHBondContact O-N 3.02Å; V374-S377 CarbonylContact O-C 3.57Å; V374-S377 PolarHBondContact O-N 3.45Å; S377-I379 PolarHBondContact O-N 3.32Å; S377-S380 WeakPolarHBondContact O-CB 3.43Å; S377-S380 PolarHBondContact O-N 3.16Å; S377-S380 PolarHBondContact O-OG 3.31Å
378	W	93.8	Very high	95.5	Very high	210 Å²	210	59.7 Å²	59.7	80%	0.795	30%	0.302	S	S	*	.	T	Hydrogen-bonded Turn	trans	-61.7	-30.4	177.3	-67.7	99.6	0	0	0	113.7	V374 S380 M381	V374-W378 HydrophobicContact CG1-CE3 4.29Å; V374-W378 HydrophobicContact CG1-CZ3 4.27Å; W378-S380 PolarHBondContact O-N 3.38Å; W378-M381 WeakPolarHBondContact O-CB 3.31Å; W378-M381 PolarHBondContact O-N 3.09Å
379	I	94.8	Very high	95.6	Very high	138 Å²	138	63.6 Å²	63.6	71%	0.708	32%	0.321	S	S	*	.	T	Hydrogen-bonded Turn	trans	-63.2	-31.6	-179.7	-60.8	168.8	0	0	0	111.2	S377 M381 I382	S377-I379 PolarHBondContact O-N 3.32Å; I379-M381 PolarHBondContact O-N 3.47Å; I379-M381 VanDerWaalsContact O-N 3.14Å; I379-I382 PolarHBondContact O-N 3.18Å
380	S	94.6	Very high	95.6	Very high	4 Å²	4	65.2 Å²	65.2	3%	0.028	33%	0.328	C	S	.	.	H	α-helix	trans	-61	-22.4	179.1	71.5	0	0	0	0	113.6	I373 S377 W378 I382 L383 L384	I373-S380 PolarHBondContact O-OG 2.8Å; I373-S380 VanDerWaalsContact O-OG 3.14Å; S377-S380 WeakPolarHBondContact O-CB 3.43Å; S377-S380 PolarHBondContact O-N 3.16Å; S377-S380 PolarHBondContact O-OG 3.31Å; W378-S380 PolarHBondContact O-N 3.38Å; S380-I382 PolarHBondContact O-N 3.15Å; S380-L383 PolarHBondContact O-N 3.11Å; S380-L383 VanDerWaalsContact O-N 3.12Å; S380-L384 WeakPolarHBondContact O-CG 3.46Å; S380-L384 PolarHBondContact O-N 3.13Å
381	M	95.3	Very high	95.5	Very high	89 Å²	89	62.9 Å²	62.9	44%	0.438	32%	0.316	S	S	.	.	H	α-helix	trans	-54.5	-39.7	179.4	-172.9	68.7	82.3	0	0	112.3	V374 W378 I379 L384 S385	V374-M381 HydrophobicContact CB-CE 4.19Å; V374-M381 HydrophobicContact CG1-CE 3.54Å; V374-M381 HydrophobicContact CG2-CE 3.48Å; V374-M381 VanDerWaalsContact CG2-CE 3.48Å; V374-M381 HydrophobicContact CG2-SD 3.74Å; W378-M381 WeakPolarHBondContact O-CB 3.31Å; W378-M381 PolarHBondContact O-N 3.09Å; I379-M381 PolarHBondContact O-N 3.47Å; I379-M381 VanDerWaalsContact O-N 3.14Å; M381-L384 PolarHBondContact O-N 3.31Å; M381-S385 WeakPolarHBondContact O-CB 2.93Å; M381-S385 PolarHBondContact O-N 3.17Å
382	I	96.1	Very high	95.5	Very high	105 Å²	105	60.1 Å²	60.1	54%	0.538	31%	0.306	S	S	.	.	H	α-helix	trans	-63.3	-48.3	-179.7	-61.6	171.7	0	0	0	109.9	I379 S380 L384 S385 F386	I379-I382 PolarHBondContact O-N 3.18Å; S380-I382 PolarHBondContact O-N 3.15Å; I382-L384 PolarHBondContact O-N 3.33Å; I382-S385 PolarHBondContact O-N 2.92Å; I382-S385 PolarHBondContact O-OG 3.09Å; I382-F386 HydrophobicContact CG2-CD2 4.06Å; I382-F386 HydrophobicContact CG2-CE2 3.68Å; I382-F386 VanDerWaalsContact O-CD2 3.23Å; I382-F386 WeakPolarHBondContact O-CD2 3.37Å; I382-F386 PolarHBondContact O-N 2.91Å
383	L	96.1	Very high	95.5	Very high	48 Å²	48	61.4 Å²	61.4	25%	0.251	32%	0.317	S	S	.	.	H	α-helix	trans	-65.6	-40.6	-179.9	-65.4	174	0	0	0	111.7	L254 V255 V258 S380 S385 F386 L387	L254-L383 HydrophobicContact CB-CB 4.21Å; L254-L383 HydrophobicContact CB-CD1 3.77Å; L254-L383 HydrophobicContact CD1-CD1 4.39Å; V255-L383 HydrophobicContact CG2-CD1 3.95Å; V255-L383 HydrophobicContact CG2-CD2 4.38Å; V258-L383 HydrophobicContact CG2-CD2 4.32Å; S380-L383 PolarHBondContact O-N 3.11Å; S380-L383 VanDerWaalsContact O-N 3.12Å; L383-S385 VanDerWaalsContact C-N 3.34Å; L383-S385 PolarHBondContact O-N 3.39Å; L383-F386 PolarHBondContact O-N 3.49Å; L383-L387 WeakPolarHBondContact O-CG 3.35Å; L383-L387 PolarHBondContact O-N 3.13Å
384	L	95.8	Very high	95.5	Very high	4 Å²	4	61.5 Å²	61.5	2%	0.021	32%	0.317	C	S	.	.	H	α-helix	trans	-62.8	-39.7	176.5	-68.6	173.2	0	0	0	112.3	L254 L370 I373 V374 S380 M381 I382 F386 L387 S388	L254-L384 HydrophobicContact CD2-CD2 3.72Å; L254-L384 HydrophobicContact CD2-CG 4.47Å; L370-L384 HydrophobicContact CD2-CB 3.79Å; L370-L384 HydrophobicContact CD2-CD1 3.91Å; L370-L384 HydrophobicContact CD2-CD2 3.92Å; L370-L384 HydrophobicContact CD2-CG 4.08Å; I373-L384 HydrophobicContact CB-CD1 3.92Å; I373-L384 HydrophobicContact CD1-CD2 3.95Å; I373-L384 HydrophobicContact CG2-CD1 3.77Å; I373-L384 HydrophobicContact CG2-CD2 4.26Å; I373-L384 HydrophobicContact CG2-CG 4.27Å; V374-L384 HydrophobicContact CG2-CD1 3.79Å; S380-L384 WeakPolarHBondContact O-CG 3.46Å; S380-L384 PolarHBondContact O-N 3.13Å; M381-L384 PolarHBondContact O-N 3.31Å; I382-L384 PolarHBondContact O-N 3.33Å; L384-F386 VanDerWaalsContact C-N 3.32Å; L384-F386 PolarHBondContact O-N 3.47Å; L384-L387 HydrophobicContact CD2-CD1 4.28Å; L384-L387 PolarHBondContact O-N 3Å; L384-S388 PolarHBondContact O-N 2.93Å; L384-S388 PolarHBondContact O-OG 3.27Å
385	S	96.1	Very high	95.5	Very high	60 Å²	60	60.5 Å²	60.5	42%	0.42	31%	0.311	S	S	.	.	H	α-helix	trans	-62.2	-39.6	176.6	75.7	0	0	0	0	112.4	M381 I382 L383 S388 F389	M381-S385 WeakPolarHBondContact O-CB 2.93Å; M381-S385 PolarHBondContact O-N 3.17Å; I382-S385 PolarHBondContact O-N 2.92Å; I382-S385 PolarHBondContact O-OG 3.09Å; L383-S385 VanDerWaalsContact C-N 3.34Å; L383-S385 PolarHBondContact O-N 3.39Å; S385-S388 PolarHBondContact O-OG 3.41Å; S385-F389 VanDerWaalsContact O-CB 3.27Å; S385-F389 WeakPolarHBondContact O-CB 3.29Å; S385-F389 PolarHBondContact O-N 3.25Å; S385-F389 VanDerWaalsContact O-N 3.09Å
386	F	96.7	Very high	95.5	Very high	97 Å²	97	61.2 Å²	61.2	43%	0.425	31%	0.308	S	S	.	.	H	α-helix	trans	-69.6	-41.3	174.6	-73.4	-56.1	0	0	0	111.8	V258 I382 L383 L384 F389 F390	V258-F386 HydrophobicContact CG1-CB 4.25Å; V258-F386 HydrophobicContact CG2-CB 4.11Å; I382-F386 HydrophobicContact CG2-CD2 4.06Å; I382-F386 HydrophobicContact CG2-CE2 3.68Å; I382-F386 VanDerWaalsContact O-CD2 3.23Å; I382-F386 WeakPolarHBondContact O-CD2 3.37Å; I382-F386 PolarHBondContact O-N 2.91Å; L383-F386 PolarHBondContact O-N 3.49Å; L384-F386 VanDerWaalsContact C-N 3.32Å; L384-F386 PolarHBondContact O-N 3.47Å; F386-F389 PolarHBondContact O-N 3.31Å; F386-F390 HydrophobicContact CB-CD2 4.11Å; F386-F390 HydrophobicContact CB-CE2 3.96Å; F386-F390 AromaticContact CD1-CE2 3.97Å; F386-F390 HydrophobicContact CD1-CE2 3.97Å; F386-F390 HydrophobicContact CD1-CZ 4.44Å; F386-F390 HydrophobicContact CG-CE2 4.3Å; F386-F390 WeakPolarHBondContact O-CB 3.31Å; F386-F390 WeakPolarHBondContact O-CD2 3.09Å; F386-F390 WeakPolarHBondContact O-CG 3.38Å; F386-F390 PolarHBondContact O-N 3.1Å
387	L	95.7	Very high	95.6	Very high	7 Å²	7	58.8 Å²	58.8	4%	0.037	30%	0.299	C	S	.	.	H	α-helix	trans	-58.2	-49.2	177.6	-77.9	166.3	0	0	0	112.3	L254 V258 I284 L383 L384 S391	L254-L387 HydrophobicContact CD2-CD1 3.81Å; V258-L387 HydrophobicContact CG2-CD1 4.43Å; V258-L387 HydrophobicContact CG2-CD2 3.9Å; V258-L387 HydrophobicContact CG2-CG 3.66Å; V258-L387 VanDerWaalsContact N-CD2 3.28Å; I284-L387 HydrophobicContact CD1-CB 4.47Å; I284-L387 HydrophobicContact CG1-CD1 4.21Å; L383-L387 WeakPolarHBondContact O-CG 3.35Å; L383-L387 PolarHBondContact O-N 3.13Å; L384-L387 HydrophobicContact CD2-CD1 4.28Å; L384-L387 PolarHBondContact O-N 3Å; L387-S391 WeakPolarHBondContact O-CB 3.41Å; L387-S391 PolarHBondContact O-N 3.27Å
388	S	94.5	Very high	95.7	Very high	53 Å²	53	57.4 Å²	57.4	37%	0.371	29%	0.289	S	S	.	.	H	α-helix	trans	-70.4	-35.6	179.9	61.6	0	0	0	0	112.6	L384 S385 S391 A392	L384-S388 PolarHBondContact O-N 2.93Å; L384-S388 PolarHBondContact O-OG 3.27Å; S385-S388 PolarHBondContact O-OG 3.41Å; S388-S391 PolarHBondContact O-OG 3.38Å; S388-A392 PolarHBondContact O-N 3.05Å
389	F	96.4	Very high	95.8	Very high	136 Å²	136	49 Å²	49	60%	0.596	26%	0.258	S	S	*	.	H	α-helix	trans	-64.7	-48.4	174.3	177.9	-98.5	0	0	0	111.8	S385 F386 S391 A392 A393	S385-F389 VanDerWaalsContact O-CB 3.27Å; S385-F389 WeakPolarHBondContact O-CB 3.29Å; S385-F389 PolarHBondContact O-N 3.25Å; S385-F389 VanDerWaalsContact O-N 3.09Å; F386-F389 PolarHBondContact O-N 3.31Å; F389-S391 VanDerWaalsContact C-N 3.31Å; F389-S391 PolarHBondContact O-N 3.01Å; F389-A392 PolarHBondContact O-N 3.06Å; F389-A393 PolarHBondContact O-N 3.19Å
390	F	96.5	Very high	95.8	Very high	33 Å²	33	44.6 Å²	44.6	15%	0.145	24%	0.239	C	C	.	.	H	α-helix	trans	-70.6	-28.3	-179.9	-68.6	-54.3	0	0	0	112.4	V258 S261 L262 L265 F386 A393 Y394	V258-F390 HydrophobicContact CG1-CD2 4.36Å; V258-F390 HydrophobicContact CG1-CE2 4.24Å; S261-F390 WeakPolarHBondContact OG-CB 3.41Å; S261-F390 WeakPolarHBondContact OG-CD2 3.5Å; L262-F390 HydrophobicContact CD2-CD1 4.18Å; L262-F390 HydrophobicContact CD2-CD2 4.38Å; L262-F390 HydrophobicContact CD2-CE1 3.67Å; L262-F390 HydrophobicContact CD2-CE2 3.91Å; L262-F390 HydrophobicContact CD2-CZ 3.54Å; L262-F390 HydrophobicContact CG-CE2 4.34Å; L262-F390 HydrophobicContact CG-CZ 4.44Å; L265-F390 HydrophobicContact CD1-CD1 4Å; L265-F390 HydrophobicContact CD1-CE1 4.38Å; F386-F390 HydrophobicContact CB-CD2 4.11Å; F386-F390 HydrophobicContact CB-CE2 3.96Å; F386-F390 AromaticContact CD1-CE2 3.97Å; F386-F390 HydrophobicContact CD1-CE2 3.97Å; F386-F390 HydrophobicContact CD1-CZ 4.44Å; F386-F390 HydrophobicContact CG-CE2 4.3Å; F386-F390 WeakPolarHBondContact O-CB 3.31Å; F386-F390 WeakPolarHBondContact O-CD2 3.09Å; F386-F390 WeakPolarHBondContact O-CG 3.38Å; F386-F390 PolarHBondContact O-N 3.1Å; F390-A393 PolarHBondContact O-N 3.29Å; F390-Y394 WeakPolarHBondContact O-CD1 3.32Å; F390-Y394 PolarHBondContact O-N 3.37Å
391	S	94.7	Very high	95.7	Very high	9 Å²	9	48.6 Å²	48.6	6%	0.063	26%	0.256	C	S	.	.	H	α-helix	trans	-60.8	-43.3	172.1	74.7	0	0	0	0	112.5	L387 S388 F389 T395	L387-S391 WeakPolarHBondContact O-CB 3.41Å; L387-S391 PolarHBondContact O-N 3.27Å; S388-S391 PolarHBondContact O-OG 3.38Å; F389-S391 VanDerWaalsContact C-N 3.31Å; F389-S391 PolarHBondContact O-N 3.01Å; S391-T395 WeakPolarHBondContact O-CB 3.43Å; S391-T395 VanDerWaalsContact O-CG2 3.28Å; S391-T395 WeakPolarHBondContact O-CG2 3.24Å; S391-T395 PolarHBondContact O-N 3.33Å; S391-T395 PolarHBondContact O-OG1 3.44Å
392	A	96.2	Very high	95.6	Very high	33 Å²	33	44.3 Å²	44.3	27%	0.273	24%	0.235	S	C	.	.	H	α-helix	trans	-65.4	-40.5	171	0	0	0	0	0	112.5	S388 F389 T395 L396	S388-A392 PolarHBondContact O-N 3.05Å; F389-A392 PolarHBondContact O-N 3.06Å; A392-T395 WeakPolarHBondContact CA-OG1 3.21Å; A392-T395 PolarHBondContact O-OG1 3.27Å; A392-L396 WeakPolarHBondContact O-CB 3.06Å; A392-L396 VanDerWaalsContact O-CG 3.31Å; A392-L396 WeakPolarHBondContact O-CG 3.23Å; A392-L396 PolarHBondContact O-N 3.26Å
393	A	97	Very high	95.5	Very high	28 Å²	28	39.4 Å²	39.4	23%	0.231	21%	0.21	C	C	.	.	H	α-helix	trans	-64.7	-49	-178.2	0	0	0	0	0	113	L265 F389 F390 T395 L396 Y397	L265-A393 HydrophobicContact CD2-CB 4.09Å; F389-A393 PolarHBondContact O-N 3.19Å; F390-A393 PolarHBondContact O-N 3.29Å; A393-T395 VanDerWaalsContact C-N 3.34Å; A393-T395 PolarHBondContact O-N 3.13Å; A393-L396 PolarHBondContact O-N 3.22Å; A393-Y397 VanDerWaalsContact O-CB 3.28Å; A393-Y397 WeakPolarHBondContact O-CB 3.36Å; A393-Y397 PolarHBondContact O-N 3.23Å
394	Y	96.6	Very high	95.3	Very high	2 Å²	2	41.7 Å²	41.7	1%	0.008	22%	0.219	C	C	.	.	H	α-helix	trans	-72.5	-27.9	-177.2	67.5	-117.3	0	0	0	113.1	C264 L273 S277 H281 F390 Y397 L398	C264-Y394 HydrophobicContact CB-CD1 3.92Å; C264-Y394 HydrophobicContact CB-CG 3.88Å; L273-Y394 HydrophobicContact CD2-CD2 4.4Å; S277-Y394 VanDerWaalsContact CB-CE2 3.46Å; H281-Y394 PolarHBondContact NE2-OH 2.98Å; F390-Y394 WeakPolarHBondContact O-CD1 3.32Å; F390-Y394 PolarHBondContact O-N 3.37Å; Y394-Y397 WeakPolarHBondContact O-CB 3.05Å; Y394-L398 WeakPolarHBondContact O-CB 3.3Å; Y394-L398 PolarHBondContact O-N 3.43Å
395	T	95.6	Very high	95.1	Very high	2 Å²	2	44 Å²	44	1%	0.012	24%	0.243	C	C	.	.	H	α-helix	trans	-73.5	-40.3	176.2	44.8	0	0	0	0	111.1	N354 M355 S391 A392 A393 Y397 L398 Y399	N354-T395 HydrophobicContact CB-CG2 3.86Å; N354-T395 VanDerWaalsContact ND2-CG2 3.3Å; N354-T395 WeakPolarHBondContact ND2-CG2 3.4Å; M355-T395 VanDerWaalsContact CE-CB 3.42Å; M355-T395 WeakPolarHBondContact CE-OG1 3.5Å; M355-T395 HydrophobicContact CG-CG2 4.11Å; M355-T395 WeakPolarHBondContact CG-OG1 3.47Å; S391-T395 WeakPolarHBondContact O-CB 3.43Å; S391-T395 VanDerWaalsContact O-CG2 3.28Å; S391-T395 WeakPolarHBondContact O-CG2 3.24Å; S391-T395 PolarHBondContact O-N 3.33Å; S391-T395 PolarHBondContact O-OG1 3.44Å; A392-T395 WeakPolarHBondContact CA-OG1 3.21Å; A392-T395 PolarHBondContact O-OG1 3.27Å; A393-T395 VanDerWaalsContact C-N 3.34Å; A393-T395 PolarHBondContact O-N 3.13Å; T395-Y397 VanDerWaalsContact C-N 3.32Å; T395-L398 PolarHBondContact O-N 3.06Å; T395-Y399 PolarHBondContact O-N 2.81Å
396	L	95.3	Very high	94.7	Very high	98 Å²	98	50.2 Å²	50.2	51%	0.513	26%	0.263	S	S	.	.	H	α-helix	trans	-66.1	-38.2	172	-74.9	172.8	0	0	0	110.6	M355 A392 A393 Y399 S400	M355-L396 HydrophobicContact CE-CB 4.22Å; M355-L396 HydrophobicContact CE-CD2 3.51Å; M355-L396 HydrophobicContact CE-CG 3.48Å; M355-L396 VanDerWaalsContact CE-CG 3.48Å; M355-L396 HydrophobicContact SD-CD2 4.17Å; M355-L396 HydrophobicContact SD-CG 4.06Å; A392-L396 WeakPolarHBondContact O-CB 3.06Å; A392-L396 VanDerWaalsContact O-CG 3.31Å; A392-L396 WeakPolarHBondContact O-CG 3.23Å; A392-L396 PolarHBondContact O-N 3.26Å; A393-L396 PolarHBondContact O-N 3.22Å; L396-Y399 PolarHBondContact O-N 2.96Å; L396-S400 VanDerWaalsContact O-CB 3.22Å; L396-S400 WeakPolarHBondContact O-CB 3.3Å; L396-S400 PolarHBondContact O-N 3.24Å; L396-S400 PolarHBondContact O-OG 2.86Å
397	Y	95.6	Very high	94.1	Very high	46 Å²	46	48.1 Å²	48.1	18%	0.18	26%	0.256	C	S	.	.	H	α-helix	trans	-59.1	-49.3	171.6	173.5	-95.5	0	0	0	111.3	L273 A393 Y394 T395 Y399 S400 F401	L273-Y397 HydrophobicContact CD1-CD1 3.7Å; L273-Y397 HydrophobicContact CD1-CE1 3.73Å; A393-Y397 VanDerWaalsContact O-CB 3.28Å; A393-Y397 WeakPolarHBondContact O-CB 3.36Å; A393-Y397 PolarHBondContact O-N 3.23Å; Y394-Y397 WeakPolarHBondContact O-CB 3.05Å; T395-Y397 VanDerWaalsContact C-N 3.32Å; Y397-Y399 PolarHBondContact O-N 3.27Å; Y397-S400 PolarHBondContact O-N 2.96Å; Y397-S400 PolarHBondContact O-OG 2.94Å; Y397-F401 AromaticContact CD2-CD2 3.27Å; Y397-F401 HydrophobicContact CD2-CD2 3.27Å; Y397-F401 AromaticContact CD2-CE2 3.15Å; Y397-F401 HydrophobicContact CD2-CE2 3.15Å; Y397-F401 HydrophobicContact CD2-CG 4.27Å; Y397-F401 HydrophobicContact CD2-CZ 4.08Å; Y397-F401 HydrophobicContact CE2-CD1 4.39Å; Y397-F401 AromaticContact CE2-CD2 3.33Å; Y397-F401 HydrophobicContact CE2-CD2 3.33Å; Y397-F401 HydrophobicContact CE2-CE1 4.25Å; Y397-F401 AromaticContact CE2-CE2 3.17Å; Y397-F401 HydrophobicContact CE2-CE2 3.17Å; Y397-F401 AromaticContact CE2-CG 3.97Å; Y397-F401 HydrophobicContact CE2-CG 3.97Å; Y397-F401 AromaticContact CE2-CZ 3.65Å; Y397-F401 HydrophobicContact CE2-CZ 3.65Å; Y397-F401 AromaticContact CG-CD2 3.97Å; Y397-F401 HydrophobicContact CG-CD2 3.97Å; Y397-F401 HydrophobicContact CG-CE2 4.24Å; Y397-F401 WeakPolarHBondContact O-CB 3.4Å; Y397-F401 WeakPolarHBondContact O-CD2 3.34Å; Y397-F401 PolarHBondContact O-N 2.63Å
398	L	96	Very high	93.6	Very high	4 Å²	4	52.5 Å²	52.5	2%	0.021	28%	0.275	C	S	.	.	H	α-helix	trans	-57.2	-46.6	176	171.6	162	0	0	0	111.7	L273 I274 W347 Y394 T395 S402	L273-L398 HydrophobicContact CD1-CB 4.43Å; L273-L398 HydrophobicContact CD2-CB 4.2Å; L273-L398 HydrophobicContact CD2-CD1 3.88Å; I274-L398 HydrophobicContact CG1-CD1 3.91Å; W347-L398 HydrophobicContact CE3-CD2 3.68Å; W347-L398 HydrophobicContact CZ3-CD1 4.44Å; W347-L398 HydrophobicContact CZ3-CD2 3.49Å; W347-L398 VanDerWaalsContact CZ3-CD2 3.49Å; W347-L398 HydrophobicContact CZ3-CG 4.27Å; Y394-L398 WeakPolarHBondContact O-CB 3.3Å; Y394-L398 PolarHBondContact O-N 3.43Å; T395-L398 PolarHBondContact O-N 3.06Å; L398-S402 WeakPolarHBondContact O-CB 3.31Å; L398-S402 PolarHBondContact O-N 2.9Å; L398-S402 PolarHBondContact O-OG 3.06Å
399	Y	96	Very high	93	Very high	33 Å²	33	55 Å²	55	13%	0.129	29%	0.292	C	S	.	.	H	α-helix	trans	-68.4	-50	-178.5	-179.3	-100.6	0	0	0	111.7	W347 F348 T395 L396 Y397 S402 Q403 H404	W347-Y399 HydrophobicContact CB-CD2 4.1Å; W347-Y399 HydrophobicContact CB-CE2 4.08Å; F348-Y399 HydrophobicContact CB-CD2 4.46Å; F348-Y399 HydrophobicContact CB-CE2 3.68Å; F348-Y399 HydrophobicContact CD2-CE1 4.41Å; F348-Y399 HydrophobicContact CD2-CE2 4.38Å; T395-Y399 PolarHBondContact O-N 2.81Å; L396-Y399 PolarHBondContact O-N 2.96Å; Y397-Y399 PolarHBondContact O-N 3.27Å; Y399-S402 PolarHBondContact O-N 3.17Å; Y399-S402 PolarHBondContact O-OG 3.48Å; Y399-Q403 HydrophobicContact CD2-CG 3.77Å; Y399-Q403 HydrophobicContact CE2-CB 4.25Å; Y399-Q403 HydrophobicContact CE2-CG 3.63Å; Y399-Q403 HydrophobicContact CG-CG 4.43Å; Y399-Q403 WeakPolarHBondContact O-CB 3.38Å; Y399-Q403 WeakPolarHBondContact O-CG 3.35Å; Y399-Q403 PolarHBondContact O-N 3.5Å; Y399-H404 AromaticContact CE1-NE2 3.66Å
400	S	94.8	Very high	92.3	Very high	45 Å²	45	50.8 Å²	50.8	32%	0.315	29%	0.287	S	S	.	.	H	α-helix	trans	-65.1	-45.6	-174.6	58.2	0	0	0	0	112.9	L396 Y397 S402 H404	L396-S400 VanDerWaalsContact O-CB 3.22Å; L396-S400 WeakPolarHBondContact O-CB 3.3Å; L396-S400 PolarHBondContact O-N 3.24Å; L396-S400 PolarHBondContact O-OG 2.86Å; Y397-S400 PolarHBondContact O-N 2.96Å; Y397-S400 PolarHBondContact O-OG 2.94Å; S400-S402 PolarHBondContact O-N 3.4Å; S400-H404 WeakPolarHBondContact O-CB 3.39Å; S400-H404 PolarHBondContact O-N 3.42Å; S400-H404 VanDerWaalsContact O-N 3.07Å
401	F	93.8	Very high	91.3	Very high	88 Å²	88	50.6 Å²	50.6	39%	0.386	29%	0.289	S	S	.	.	H	α-helix	trans	-71.9	-29.9	-179.2	-81.4	-95	0	0	0	112.7	M330 K334 Y397	M330-F401 HydrophobicContact CE-CB 3.33Å; M330-F401 HydrophobicContact CE-CG 4.47Å; K334-F401 WeakPolarHBondContact CG-O 3.43Å; Y397-F401 AromaticContact CD2-CD2 3.27Å; Y397-F401 HydrophobicContact CD2-CD2 3.27Å; Y397-F401 AromaticContact CD2-CE2 3.15Å; Y397-F401 HydrophobicContact CD2-CE2 3.15Å; Y397-F401 HydrophobicContact CD2-CG 4.27Å; Y397-F401 HydrophobicContact CD2-CZ 4.08Å; Y397-F401 HydrophobicContact CE2-CD1 4.39Å; Y397-F401 AromaticContact CE2-CD2 3.33Å; Y397-F401 HydrophobicContact CE2-CD2 3.33Å; Y397-F401 HydrophobicContact CE2-CE1 4.25Å; Y397-F401 AromaticContact CE2-CE2 3.17Å; Y397-F401 HydrophobicContact CE2-CE2 3.17Å; Y397-F401 AromaticContact CE2-CG 3.97Å; Y397-F401 HydrophobicContact CE2-CG 3.97Å; Y397-F401 AromaticContact CE2-CZ 3.65Å; Y397-F401 HydrophobicContact CE2-CZ 3.65Å; Y397-F401 AromaticContact CG-CD2 3.97Å; Y397-F401 HydrophobicContact CG-CD2 3.97Å; Y397-F401 HydrophobicContact CG-CE2 4.24Å; Y397-F401 WeakPolarHBondContact O-CB 3.4Å; Y397-F401 WeakPolarHBondContact O-CD2 3.34Å; Y397-F401 PolarHBondContact O-N 2.63Å
402	S	93	Very high	90.1	Very high	0 Å²	0	59.6 Å²	59.6	0%	0	32%	0.323	C	S	.	.	H	α-helix	trans	-81.9	-43.4	178.4	61.6	0	0	0	0	113.2	N333 K334 G335 L336 L398 Y399 S400	N333-S402 CarbonylContact O-C 3.55Å; N333-S402 VanDerWaalsContact O-CA 3.26Å; N333-S402 WeakPolarHBondContact O-CA 3.38Å; K334-S402 CarbonylContact C-O 3.45Å; G335-S402 PolarHBondContact N-O 3.28Å; G335-S402 VanDerWaalsContact N-O 3.17Å; L336-S402 PolarHBondContact N-O 3.28Å; L398-S402 WeakPolarHBondContact O-CB 3.31Å; L398-S402 PolarHBondContact O-N 2.9Å; L398-S402 PolarHBondContact O-OG 3.06Å; Y399-S402 PolarHBondContact O-N 3.17Å; Y399-S402 PolarHBondContact O-OG 3.48Å; S400-S402 PolarHBondContact O-N 3.4Å
403	Q	93.7	Very high	88.5	Confident	1 Å²	1	60.6 Å²	60.6	1%	0.005	33%	0.328	C	S	.	.	H	α-helix	trans	-92.4	-38	-170.9	-53	-48	-48.5	0	0	113.2	G335 L336 L337 T344 W347 Y399	G335-Q403 CarbonylContact C-O 3.16Å; G335-Q403 VanDerWaalsContact CA-O 3.27Å; G335-Q403 WeakPolarHBondContact CA-O 3.48Å; L336-Q403 PolarHBondContact N-O 2.93Å; L337-Q403 WeakPolarHBondContact CB-O 3.27Å; L337-Q403 PolarHBondContact N-O 3.02Å; L337-Q403 VanDerWaalsContact N-O 3.07Å; T344-Q403 HydrophobicContact CG2-CG 4.48Å; W347-Q403 HydrophobicContact CB-CG 4.22Å; W347-Q403 VanDerWaalsContact CD1-NE2 3.26Å; W347-Q403 HydrophobicContact CG-CG 4.41Å; W347-Q403 VanDerWaalsContact CG-NE2 3.29Å; Y399-Q403 HydrophobicContact CD2-CG 3.77Å; Y399-Q403 HydrophobicContact CE2-CB 4.25Å; Y399-Q403 HydrophobicContact CE2-CG 3.63Å; Y399-Q403 HydrophobicContact CG-CG 4.43Å; Y399-Q403 WeakPolarHBondContact O-CB 3.38Å; Y399-Q403 WeakPolarHBondContact O-CG 3.35Å; Y399-Q403 PolarHBondContact O-N 3.5Å
404	H	92	Very high	86.9	Confident	97 Å²	97	65.2 Å²	65.2	45%	0.449	34%	0.343	S	S	.	.	S	Bend	trans	-90	164.3	-177.3	-63.3	-60.1	0	0	0	112.8	G335 Y399 S400	G335-H404 WeakPolarHBondContact CA-O 3.47Å; G335-H404 PolarHBondContact N-O 2.86Å; G335-H404 VanDerWaalsContact N-O 3.08Å; Y399-H404 AromaticContact CE1-NE2 3.66Å; S400-H404 WeakPolarHBondContact O-CB 3.39Å; S400-H404 PolarHBondContact O-N 3.42Å; S400-H404 VanDerWaalsContact O-N 3.07Å
405	G	90.5	Very high	86.1	Confident	51 Å²	51	67.8 Å²	67.8	53%	0.526	36%	0.361	S	S	.	.	S	Bend	trans	99.6	-173.8	174.8	0	0	0	0	0	114.4	G335	G335-G405 WeakPolarHBondContact CA-O 2.85Å
406	K	87.5	Confident	85.4	Confident	191 Å²	191	71.4 Å²	71.4	83%	0.83	39%	0.387	S	S	*	.	P	Polyproline II helix	trans	-80	144.6	176.8	-65.5	-178.6	-178.1	179.1	0	109.9
407	L	85.4	Confident	84.9	Confident	53 Å²	53	67.6 Å²	67.6	28%	0.277	37%	0.371	S	S	.	.	P	Polyproline II helix	trans	-68.2	142.4	177.6	-64.3	164.4	0	0	0	110.3	K334 G335 N338 F339 S409	K334-L407 WeakPolarHBondContact O-CD2 3.24Å; G335-L407 WeakPolarHBondContact O-CD2 3.46Å; N338-L407 HydrophobicContact CB-CD1 3.68Å; N338-L407 HydrophobicContact CB-CD2 4.38Å; N338-L407 HydrophobicContact CB-CG 4.21Å; F339-L407 HydrophobicContact CD1-CD1 3.66Å; F339-L407 HydrophobicContact CD1-CD2 4.4Å; F339-L407 HydrophobicContact CD2-CD1 4.01Å; F339-L407 HydrophobicContact CD2-CD2 3.18Å; F339-L407 HydrophobicContact CD2-CG 4.06Å; F339-L407 HydrophobicContact CE1-CD1 3.13Å; F339-L407 HydrophobicContact CE1-CD2 4.25Å; F339-L407 HydrophobicContact CE1-CG 4.09Å; F339-L407 HydrophobicContact CE2-CB 3.78Å; F339-L407 HydrophobicContact CE2-CD1 3.57Å; F339-L407 HydrophobicContact CE2-CD2 3.02Å; F339-L407 HydrophobicContact CE2-CG 3.55Å; F339-L407 HydrophobicContact CG-CD1 4.06Å; F339-L407 HydrophobicContact CG-CD2 3.91Å; F339-L407 HydrophobicContact CZ-CB 3.66Å; F339-L407 HydrophobicContact CZ-CD1 3.06Å; F339-L407 HydrophobicContact CZ-CD2 3.58Å; F339-L407 HydrophobicContact CZ-CG 3.52Å; L407-S409 PolarHBondContact O-N 3.18Å
408	F	84.7	Confident	84.7	Confident	99 Å²	99	69 Å²	69	43%	0.434	38%	0.378	S	S	.	.	P	Polyproline II helix	trans	-69.5	122	174.3	-177.8	-103.8	0	0	0	109.8	I332 G410 V411	I332-F408 HydrophobicContact CG2-CD1 4.24Å; F408-G410 PolarHBondContact O-N 2.87Å; F408-V411 HydrophobicContact CD1-CG2 3.95Å; F408-V411 HydrophobicContact CE1-CG2 4.36Å
409	S	82.8	Confident	84.5	Confident	106 Å²	106	75.9 Å²	75.9	74%	0.741	41%	0.413	S	S	*	.	T	Hydrogen-bonded Turn	trans	-68.7	-16.6	-171.9	55.1	0	0	0	0	114.6	L407 V411	L407-S409 PolarHBondContact O-N 3.18Å; S409-V411 PolarHBondContact O-N 2.94Å
410	G	80.4	Confident	84.4	Confident	48 Å²	48	75.9 Å²	75.9	50%	0.495	41%	0.413	S	S	.	.	T	Hydrogen-bonded Turn	trans	-84	1.5	-174.6	0	0	0	0	0	115.8	F408	F408-G410 PolarHBondContact O-N 2.87Å
411	V	75.3	Confident	84.4	Confident	28 Å²	28	74 Å²	74	17%	0.17	40%	0.399	C	S	.	.			trans	-123.3	130.6	-176.3	-178.1	0	0	0	0	111.3	L325 I332 F408 S409 S413	L325-V411 HydrophobicContact CD2-CB 4.15Å; L325-V411 HydrophobicContact CD2-CG1 3.53Å; L325-V411 HydrophobicContact CD2-CG2 4.46Å; I332-V411 HydrophobicContact CG2-CG2 4.25Å; F408-V411 HydrophobicContact CD1-CG2 3.95Å; F408-V411 HydrophobicContact CE1-CG2 4.36Å; S409-V411 PolarHBondContact O-N 2.94Å; V411-S413 VanDerWaalsContact CG1-OG 3.27Å; V411-S413 WeakPolarHBondContact CG1-OG 3.35Å
412	Y	69.2	Low	84.5	Confident	198 Å²	198	72.3 Å²	72.3	78%	0.776	39%	0.391	S	S	*	.			trans	-113.4	4.7	-174.8	-69.5	-79.1	0	0	0	114.4	F414	Y412-F414 WeakPolarHBondContact O-CD2 3.37Å; Y412-F414 WeakPolarHBondContact O-CE2 3.11Å; Y412-F414 PolarHBondContact O-N 2.91Å
413	S	64	Low	84.7	Confident	54 Å²	54	76.1 Å²	76.1	38%	0.378	41%	0.411	S	S	.	.			trans	-87.7	107.6	-176	44.6	0	0	0	0	111.8	R324 V411	R324-S413 WeakPolarHBondContact O-CB 3.23Å; R324-S413 PolarHBondContact O-OG 3.14Å; V411-S413 VanDerWaalsContact CG1-OG 3.27Å; V411-S413 WeakPolarHBondContact CG1-OG 3.35Å
414	F	63.8	Low	84.8	Confident	125 Å²	125	76.2 Å²	76.2	55%	0.548	41%	0.411	S	S	.	.			trans	-115.1	118.7	-179.2	-53.4	-54.7	0	0	0	112	F339 Y412	F339-F414 AromaticContact CD1-CD1 3.74Å; F339-F414 HydrophobicContact CD1-CD1 3.74Å; F339-F414 AromaticContact CD1-CE1 3.74Å; F339-F414 HydrophobicContact CD1-CE1 3.74Å; F339-F414 HydrophobicContact CD2-CD1 4.46Å; F339-F414 HydrophobicContact CD2-CE1 4.23Å; F339-F414 AromaticContact CE1-CD1 3.65Å; F339-F414 HydrophobicContact CE1-CD1 3.65Å; F339-F414 AromaticContact CE1-CE1 3.14Å; F339-F414 HydrophobicContact CE1-CE1 3.14Å; F339-F414 AromaticContact CE1-CZ 3.78Å; F339-F414 HydrophobicContact CE1-CZ 3.78Å; F339-F414 HydrophobicContact CE2-CD1 4.34Å; F339-F414 AromaticContact CE2-CE1 3.68Å; F339-F414 HydrophobicContact CE2-CE1 3.68Å; F339-F414 HydrophobicContact CG-CD1 4.18Å; F339-F414 HydrophobicContact CG-CE1 4.26Å; F339-F414 AromaticContact CZ-CD1 3.99Å; F339-F414 HydrophobicContact CZ-CD1 3.99Å; F339-F414 AromaticContact CZ-CE1 3.13Å; F339-F414 HydrophobicContact CZ-CE1 3.13Å; F339-F414 AromaticContact CZ-CZ 3.79Å; F339-F414 HydrophobicContact CZ-CZ 3.79Å; Y412-F414 WeakPolarHBondContact O-CD2 3.37Å; Y412-F414 WeakPolarHBondContact O-CE2 3.11Å; Y412-F414 PolarHBondContact O-N 2.91Å
415	S	79.5	Confident	85	Confident	57 Å²	57	71.6 Å²	71.6	40%	0.399	39%	0.39	S	S	.	.			trans	-140.7	131.4	160.1	60.8	0	0	0	0	108.5	R324 G417	R324-S415 WeakPolarHBondContact CD-O 3.34Å; R324-S415 WeakPolarHBondContact CD-OG 3.28Å; R324-S415 PolarHBondContact NE-O 3.16Å; R324-S415 PolarHBondContact NE-OG 3.17Å; R324-S415 VanDerWaalsContact NE-OG 3.07Å; S415-G417 PolarHBondContact O-N 2.62Å
416	S	79.9	Confident	85.3	Confident	78 Å²	78	72.6 Å²	72.6	55%	0.545	38%	0.383	S	S	.	.			trans	-68.5	-22.7	-177.4	53	0	0	0	0	113.2	Y422	S416-Y422 PolarHBondContact O-OH 3.32Å
417	G	85.4	Confident	85.7	Confident	18 Å²	18	65.1 Å²	65.1	19%	0.186	35%	0.351	C	S	.	.			trans	136	148.4	178.8	0	0	0	0	0	112	S415	S415-G417 PolarHBondContact O-N 2.62Å
418	K	90.3	Very high	86.2	Confident	74 Å²	74	62.6 Å²	62.6	32%	0.322	34%	0.338	S	S	.	.			trans	-93.5	150.7	177.8	-59.4	176.2	-168.5	131.9	0	110.6	R420 E421 Y422	K418-R420 PolarHBondContact O-N 3.27Å; K418-E421 HydrophobicContact CB-CG 4.22Å; K418-E421 WeakPolarHBondContact CD-OE1 3.48Å; K418-E421 PolarHBondContact N-OE2 2.93Å; K418-E421 IonicContact NZ-OE1 2.68Å; K418-E421 WeakPolarHBondContact O-CB 3.45Å; K418-E421 PolarHBondContact O-N 2.98Å; K418-Y422 VanDerWaalsContact O-CD2 3.23Å; K418-Y422 WeakPolarHBondContact O-CD2 3.39Å; K418-Y422 PolarHBondContact O-N 3.43Å
419	I	93.3	Very high	86.7	Confident	150 Å²	150	61.3 Å²	61.3	77%	0.769	33%	0.331	S	S	*	.	H	α-helix	trans	-52.8	-41	175.8	-62.6	171.4	0	0	0	111.5	E421 Y422 L423	I419-E421 VanDerWaalsContact C-N 3.3Å; I419-E421 PolarHBondContact O-N 3.46Å; I419-Y422 PolarHBondContact O-N 3.23Å; I419-L423 PolarHBondContact O-N 3.37Å
420	R	93.7	Very high	87.3	Confident	32 Å²	32	59.5 Å²	59.5	12%	0.121	31%	0.312	C	S	.	.	H	α-helix	trans	-53.6	-44.4	174.5	178.2	-166.5	65.2	124	-5.5	112.9	L74 A75 E77 E323 K418 L423 L424	L74-R420 HydrophobicContact CD2-CG 4.39Å; L74-R420 WeakPolarHBondContact O-CD 3.3Å; L74-R420 PolarHBondContact O-NH1 3.13Å; A75-R420 PolarHBondContact O-NH1 3.23Å; E77-R420 VanDerWaalsContact CB-CZ 3.44Å; E77-R420 IonicContact OE2-CZ 3.52Å; E77-R420 IonicContact OE2-NE 3.03Å; E77-R420 PolarHBondContact OE2-NE 3.36Å; E77-R420 IonicContact OE2-NH1 2.83Å; E77-R420 IonicContact OE2-NH2 3.59Å; E77-R420 PolarHBondContact OE2-NH2 3.24Å; E323-R420 IonicContact OE2-NH2 3.91Å; K418-R420 PolarHBondContact O-N 3.27Å; R420-L423 PolarHBondContact O-N 3.02Å; R420-L424 WeakPolarHBondContact O-CB 3.31Å; R420-L424 PolarHBondContact O-N 3.15Å
421	E	94.9	Very high	87.9	Confident	6 Å²	6	58.1 Å²	58.1	3%	0.028	29%	0.294	C	S	.	.	H	α-helix	trans	-68.5	-41.8	-176.7	-65.4	158.6	-164.2	0	0	109.7	V320 R324 M343 K418 I419 L424 M425	V320-E421 HydrophobicContact CG2-CB 4.31Å; V320-E421 HydrophobicContact CG2-CG 3.98Å; R324-E421 IonicContact CZ-OE2 3.88Å; R324-E421 IonicContact NH2-OE2 2.73Å; R324-E421 PolarHBondContact NH2-OE2 3.09Å; M343-E421 HydrophobicContact CE-CB 3.35Å; M343-E421 HydrophobicContact CE-CG 4.4Å; M343-E421 WeakPolarHBondContact CE-OE2 3.26Å; K418-E421 HydrophobicContact CB-CG 4.22Å; K418-E421 WeakPolarHBondContact CD-OE1 3.48Å; K418-E421 PolarHBondContact N-OE2 2.93Å; K418-E421 IonicContact NZ-OE1 2.68Å; K418-E421 WeakPolarHBondContact O-CB 3.45Å; K418-E421 PolarHBondContact O-N 2.98Å; I419-E421 VanDerWaalsContact C-N 3.3Å; I419-E421 PolarHBondContact O-N 3.46Å; E421-L424 PolarHBondContact O-N 3.06Å; E421-M425 VanDerWaalsContact O-CG 3.31Å; E421-M425 WeakPolarHBondContact O-CG 3.45Å; E421-M425 PolarHBondContact O-N 3.44Å
422	Y	95.4	Very high	88.8	Confident	53 Å²	53	56.8 Å²	56.8	21%	0.208	29%	0.286	C	S	.	.	H	α-helix	trans	-63.1	-42.5	173.8	-64.6	-61.6	0	0	0	112.8	S342 M343 W346 S416 K418 I419 L424 M425 L426	S342-Y422 WeakPolarHBondContact CB-OH 3.11Å; S342-Y422 PolarHBondContact OG-OH 3.35Å; M343-Y422 HydrophobicContact CE-CD1 3.76Å; M343-Y422 HydrophobicContact CE-CD2 4.29Å; M343-Y422 HydrophobicContact CE-CE1 3.49Å; M343-Y422 VanDerWaalsContact CE-CE1 3.49Å; M343-Y422 HydrophobicContact CE-CE2 4.03Å; M343-Y422 HydrophobicContact CE-CG 4.16Å; M343-Y422 HydrophobicContact CG-CE1 3.93Å; M343-Y422 HydrophobicContact SD-CD1 3.92Å; M343-Y422 HydrophobicContact SD-CE1 3.52Å; M343-Y422 VanDerWaalsContact SD-CE1 3.52Å; W346-Y422 AromaticContact CD1-CD1 3.81Å; W346-Y422 AromaticContact NE1-CD1 3.45Å; S416-Y422 PolarHBondContact O-OH 3.32Å; K418-Y422 VanDerWaalsContact O-CD2 3.23Å; K418-Y422 WeakPolarHBondContact O-CD2 3.39Å; K418-Y422 PolarHBondContact O-N 3.43Å; I419-Y422 PolarHBondContact O-N 3.23Å; Y422-L424 VanDerWaalsContact C-N 3.33Å; Y422-L424 PolarHBondContact O-N 2.91Å; Y422-M425 PolarHBondContact O-N 3.46Å; Y422-L426 WeakPolarHBondContact O-CB 3.31Å; Y422-L426 PolarHBondContact O-N 2.99Å
423	L	96	Very high	89.9	Confident	80 Å²	80	48.8 Å²	48.8	42%	0.419	26%	0.257	S	S	.	.	H	α-helix	trans	-61.7	-43	175.7	179.9	129.4	0	0	0	111.1	L74 I419 R420 M425 L426 L427	L74-L423 HydrophobicContact CD1-CD2 3.65Å; L74-L423 HydrophobicContact CD2-CD2 4.06Å; I419-L423 PolarHBondContact O-N 3.37Å; R420-L423 PolarHBondContact O-N 3.02Å; L423-M425 PolarHBondContact O-N 3.09Å; L423-L426 PolarHBondContact O-N 3.09Å; L423-L427 HydrophobicContact CD2-CD1 3.66Å; L423-L427 HydrophobicContact CG-CD1 4.1Å; L423-L427 WeakPolarHBondContact O-CB 3.25Å; L423-L427 VanDerWaalsContact O-CG 3.26Å; L423-L427 WeakPolarHBondContact O-CG 3.34Å; L423-L427 PolarHBondContact O-N 3.19Å
424	L	96.6	Very high	91.3	Very high	2 Å²	2	50.8 Å²	50.8	1%	0.01	26%	0.263	C	S	.	.	H	α-helix	trans	-60	-47.1	175.3	-176.2	156.9	0	0	0	111.2	L71 L74 A75 C316 R420 E421 Y422 L426 L427 H428	L71-L424 HydrophobicContact CD2-CG 4.48Å; L74-L424 HydrophobicContact CB-CD1 4.1Å; A75-L424 HydrophobicContact CB-CD1 3.62Å; C316-L424 HydrophobicContact CB-CD2 3.52Å; C316-L424 VanDerWaalsContact SG-CD1 3.51Å; C316-L424 WeakPolarHBondContact SG-CD2 3.23Å; R420-L424 WeakPolarHBondContact O-CB 3.31Å; R420-L424 PolarHBondContact O-N 3.15Å; E421-L424 PolarHBondContact O-N 3.06Å; Y422-L424 VanDerWaalsContact C-N 3.33Å; Y422-L424 PolarHBondContact O-N 2.91Å; L424-L426 PolarHBondContact O-N 2.9Å; L424-L427 PolarHBondContact O-N 3.31Å; L424-H428 WeakPolarHBondContact CD2-CE1 3.27Å; L424-H428 WeakPolarHBondContact CD2-ND1 3.29Å; L424-H428 PolarHBondContact O-N 3.17Å; L424-H428 PolarHBondContact O-ND1 3.34Å
425	M	96.1	Very high	92.5	Very high	1 Å²	1	46.9 Å²	46.9	1%	0.005	25%	0.248	C	C	.	.	H	α-helix	trans	-63	-43.7	180	-63.8	-39.8	-55.2	0	0	112.2	C316 L317 W346 L350 E421 Y422 L423 L427 H428 W429	C316-M425 HydrophobicContact CB-SD 4.41Å; L317-M425 HydrophobicContact CD1-CE 3.79Å; L317-M425 HydrophobicContact CD2-CE 3.58Å; L317-M425 HydrophobicContact CD2-CG 4.12Å; L317-M425 HydrophobicContact CD2-SD 3.66Å; L317-M425 HydrophobicContact CG-CE 3.34Å; L317-M425 HydrophobicContact CG-SD 3.83Å; W346-M425 HydrophobicContact CB-CB 4.2Å; W346-M425 HydrophobicContact CB-CG 4.15Å; W346-M425 HydrophobicContact CD2-CB 3.69Å; W346-M425 HydrophobicContact CD2-CG 4.5Å; W346-M425 HydrophobicContact CE3-CB 3.89Å; W346-M425 HydrophobicContact CG-CB 3.83Å; W346-M425 HydrophobicContact CG-CG 4.12Å; L350-M425 HydrophobicContact CD1-CE 3.11Å; L350-M425 HydrophobicContact CG-CE 4.2Å; E421-M425 VanDerWaalsContact O-CG 3.31Å; E421-M425 WeakPolarHBondContact O-CG 3.45Å; E421-M425 PolarHBondContact O-N 3.44Å; Y422-M425 PolarHBondContact O-N 3.46Å; L423-M425 PolarHBondContact O-N 3.09Å; M425-L427 VanDerWaalsContact C-N 3.32Å; M425-L427 PolarHBondContact O-N 3.49Å; M425-H428 PolarHBondContact O-N 3.28Å; M425-W429 PolarHBondContact O-N 3.46Å; M425-W429 VanDerWaalsContact O-N 3.07Å
426	L	96.8	Very high	93.1	Very high	72 Å²	72	46 Å²	46	38%	0.377	24%	0.238	S	C	.	.	H	α-helix	trans	-56.9	-46	175.6	-176	82.6	0	0	0	111.1	W346 Y422 L423 L424 H428 W429 L430	W346-L426 HydrophobicContact CH2-CB 4.09Å; W346-L426 HydrophobicContact CH2-CD1 3.68Å; W346-L426 HydrophobicContact CZ2-CD1 4.4Å; Y422-L426 WeakPolarHBondContact O-CB 3.31Å; Y422-L426 PolarHBondContact O-N 2.99Å; L423-L426 PolarHBondContact O-N 3.09Å; L424-L426 PolarHBondContact O-N 2.9Å; L426-H428 VanDerWaalsContact C-N 3.26Å; L426-H428 PolarHBondContact O-N 3.31Å; L426-W429 PolarHBondContact O-N 2.98Å; L426-L430 WeakPolarHBondContact O-CB 3.49Å; L426-L430 PolarHBondContact O-N 3.28Å
427	L	96.5	Very high	93.6	Very high	33 Å²	33	49.4 Å²	49.4	17%	0.173	25%	0.25	C	C	.	.	H	α-helix	trans	-69.5	-17.3	-178.4	-69.7	172.4	0	0	0	114.3	F29 W67 L71 L74 L423 L424 M425 P431	F29-L427 HydrophobicContact CE1-CD1 4.09Å; F29-L427 HydrophobicContact CZ-CD1 3.86Å; W67-L427 HydrophobicContact CH2-CD2 4.02Å; W67-L427 HydrophobicContact CZ2-CB 4.16Å; W67-L427 HydrophobicContact CZ2-CD2 3.76Å; W67-L427 PolarHBondContact NE1-O 3.39Å; L71-L427 HydrophobicContact CD2-CB 3.54Å; L71-L427 HydrophobicContact CD2-CD1 3.79Å; L71-L427 HydrophobicContact CD2-CG 4.33Å; L74-L427 HydrophobicContact CD1-CD1 3.94Å; L423-L427 HydrophobicContact CD2-CD1 3.66Å; L423-L427 HydrophobicContact CG-CD1 4.1Å; L423-L427 WeakPolarHBondContact O-CB 3.25Å; L423-L427 VanDerWaalsContact O-CG 3.26Å; L423-L427 WeakPolarHBondContact O-CG 3.34Å; L423-L427 PolarHBondContact O-N 3.19Å; L424-L427 PolarHBondContact O-N 3.31Å; M425-L427 VanDerWaalsContact C-N 3.32Å; M425-L427 PolarHBondContact O-N 3.49Å; L427-P431 WeakPolarHBondContact O-CD 3.23Å; L427-P431 VanDerWaalsContact O-CG 3.22Å; L427-P431 WeakPolarHBondContact O-CG 3.45Å
428	H	95.9	Very high	93.7	Very high	0 Å²	0	53.6 Å²	53.6	0%	0	26%	0.263	C	S	.	.	H	α-helix	trans	-84.2	-43.9	169.2	-71.5	79.4	0	0	0	111.4	M217 L309 S312 G313 L424 M425 L426	M217-H428 WeakPolarHBondContact CE-NE2 3.41Å; L309-H428 PolarHBondContact O-CD2 3.16Å; S312-H428 PolarHBondContact OG-CD2 3.06Å; S312-H428 VanDerWaalsContact OG-CD2 3.23Å; S312-H428 PolarHBondContact OG-NE2 3.04Å; G313-H428 PolarHBondContact N-CD2 3.45Å; G313-H428 VanDerWaalsContact N-CD2 3.25Å; L424-H428 WeakPolarHBondContact CD2-CE1 3.27Å; L424-H428 WeakPolarHBondContact CD2-ND1 3.29Å; L424-H428 PolarHBondContact O-N 3.17Å; L424-H428 PolarHBondContact O-ND1 3.34Å; M425-H428 PolarHBondContact O-N 3.28Å; L426-H428 VanDerWaalsContact C-N 3.26Å; L426-H428 PolarHBondContact O-N 3.31Å
429	W	94.9	Very high	93.6	Very high	72 Å²	72	51.8 Å²	51.8	27%	0.273	26%	0.259	S	S	.	.	H	α-helix	trans	-75	-41	-173.6	-177.5	83.7	0	0	0	113.1	W346 L349 L350 M425 L426 L432 N433	W346-W429 HydrophobicContact CE3-CB 4.44Å; W346-W429 HydrophobicContact CZ3-CB 3.96Å; W346-W429 HydrophobicContact CZ3-CD2 4.26Å; W346-W429 HydrophobicContact CZ3-CE3 4.4Å; W346-W429 HydrophobicContact CZ3-CG 4.11Å; L349-W429 HydrophobicContact CD1-CD2 4.4Å; L349-W429 HydrophobicContact CD1-CZ2 4.21Å; L349-W429 HydrophobicContact CD2-CZ2 4.04Å; L350-W429 HydrophobicContact CD2-CB 4.44Å; M425-W429 PolarHBondContact O-N 3.46Å; M425-W429 VanDerWaalsContact O-N 3.07Å; L426-W429 PolarHBondContact O-N 2.98Å; W429-L432 PolarHBondContact O-N 3.07Å; W429-N433 WeakPolarHBondContact CZ2-ND2 3.08Å; W429-N433 PolarHBondContact NE1-ND2 2.86Å; W429-N433 VanDerWaalsContact NE1-ND2 3.15Å; W429-N433 PolarHBondContact O-N 3.47Å
430	L	95	Very high	93.2	Very high	69 Å²	69	50.9 Å²	50.9	36%	0.361	25%	0.252	S	S	.	.	H	α-helix	trans	-62.2	-49.4	-175.8	178.1	157.8	0	0	0	112.2	L426 L432 N433 L434	L426-L430 WeakPolarHBondContact O-CB 3.49Å; L426-L430 PolarHBondContact O-N 3.28Å; L430-L432 VanDerWaalsContact C-N 3.32Å; L430-L432 PolarHBondContact O-N 3.4Å; L430-N433 PolarHBondContact O-N 3.12Å; L430-L434 HydrophobicContact CD2-CD1 3.3Å; L430-L434 HydrophobicContact CD2-CG 4.08Å; L430-L434 HydrophobicContact CG-CD1 3.75Å; L430-L434 HydrophobicContact CG-CG 4.19Å; L430-L434 WeakPolarHBondContact O-CB 3.02Å; L430-L434 WeakPolarHBondContact O-CG 3.43Å; L430-L434 PolarHBondContact O-N 3.04Å
431	P	93.5	Very high	92.6	Very high	18 Å²	18	49.7 Å²	49.7	12%	0.117	25%	0.249	C	C	.	.	H	α-helix	trans	-62.2	-38.6	176.3	-22.9	34.3	0	0	0	112.6	W67 L309 L427 N433 L434 L435	W67-P431 HydrophobicContact CZ2-CG 3.64Å; L309-P431 HydrophobicContact CD1-CB 4Å; L427-P431 WeakPolarHBondContact O-CD 3.23Å; L427-P431 VanDerWaalsContact O-CG 3.22Å; L427-P431 WeakPolarHBondContact O-CG 3.45Å; P431-N433 VanDerWaalsContact C-N 3.25Å; P431-N433 PolarHBondContact O-N 3.49Å; P431-L434 PolarHBondContact O-N 3.34Å; P431-L435 VanDerWaalsContact O-CB 3.26Å; P431-L435 WeakPolarHBondContact O-CB 3.38Å; P431-L435 WeakPolarHBondContact O-CG 3.46Å; P431-L435 PolarHBondContact O-N 3.43Å
432	L	93.4	Very high	91.8	Very high	0 Å²	0	49.9 Å²	49.9	0%	0	25%	0.249	C	C	.	.	H	α-helix	trans	-58.7	-37.3	-178.8	-172.8	153	0	0	0	112.4	L309 C310 A353 T360 W429 L430	L309-L432 HydrophobicContact CB-CD1 4.36Å; L309-L432 HydrophobicContact CD1-CB 4.4Å; C310-L432 HydrophobicContact CB-CD1 3.76Å; A353-L432 HydrophobicContact CB-CD1 4.12Å; A353-L432 HydrophobicContact CB-CD2 3.98Å; T360-L432 HydrophobicContact CG2-CD2 3.81Å; W429-L432 PolarHBondContact O-N 3.07Å; L430-L432 VanDerWaalsContact C-N 3.32Å; L430-L432 PolarHBondContact O-N 3.4Å
433	N	93.1	Very high	91.2	Very high	30 Å²	30	47.9 Å²	47.9	16%	0.16	24%	0.242	C	C	.	.	H	α-helix	trans	-91.2	-35.5	179.8	-67.1	-16	0	0	0	113.4	W429 L430 P431	W429-N433 WeakPolarHBondContact CZ2-ND2 3.08Å; W429-N433 PolarHBondContact NE1-ND2 2.86Å; W429-N433 VanDerWaalsContact NE1-ND2 3.15Å; W429-N433 PolarHBondContact O-N 3.47Å; L430-N433 PolarHBondContact O-N 3.12Å; P431-N433 VanDerWaalsContact C-N 3.25Å; P431-N433 PolarHBondContact O-N 3.49Å
434	L	92.5	Very high	90.5	Very high	97 Å²	97	48.3 Å²	48.3	51%	0.508	24%	0.244	S	C	.	.	H	α-helix	trans	-69.5	-34.8	179	-72	-172.7	0	0	0	112.7	L430 P431 I436 L437	L430-L434 HydrophobicContact CD2-CD1 3.3Å; L430-L434 HydrophobicContact CD2-CG 4.08Å; L430-L434 HydrophobicContact CG-CD1 3.75Å; L430-L434 HydrophobicContact CG-CG 4.19Å; L430-L434 WeakPolarHBondContact O-CB 3.02Å; L430-L434 WeakPolarHBondContact O-CG 3.43Å; L430-L434 PolarHBondContact O-N 3.04Å; P431-L434 PolarHBondContact O-N 3.34Å; L434-I436 PolarHBondContact O-N 3.35Å; L434-I436 VanDerWaalsContact O-N 3.12Å; L434-L437 HydrophobicContact CD2-CD1 4.26Å; L434-L437 WeakPolarHBondContact O-CB 3.46Å; L434-L437 PolarHBondContact O-N 3.2Å; L434-L437 VanDerWaalsContact O-N 3.12Å
435	L	90.7	Very high	89.8	Confident	43 Å²	43	48.8 Å²	48.8	23%	0.225	25%	0.246	C	C	.	.	G	3₁₀ helix	trans	-62.1	-21.8	-177.1	-76	176.5	0	0	0	113.6	I305 L309 L361 P431 L437 K438 S439 F442	I305-L435 HydrophobicContact CG2-CD1 4.39Å; L309-L435 HydrophobicContact CD1-CD1 4.34Å; L361-L435 HydrophobicContact CD1-CB 4.22Å; P431-L435 VanDerWaalsContact O-CB 3.26Å; P431-L435 WeakPolarHBondContact O-CB 3.38Å; P431-L435 WeakPolarHBondContact O-CG 3.46Å; P431-L435 PolarHBondContact O-N 3.43Å; L435-L437 VanDerWaalsContact C-N 3.29Å; L435-L437 PolarHBondContact O-N 3.09Å; L435-K438 CarbonylContact O-C 3.53Å; L435-K438 PolarHBondContact O-N 3.29Å; L435-S439 PolarHBondContact O-N 3.01Å; L435-F442 HydrophobicContact CB-CE2 3.95Å; L435-F442 HydrophobicContact CD1-CE2 4.19Å; L435-F442 HydrophobicContact CD1-CZ 4Å; L435-F442 HydrophobicContact CD2-CE2 3.83Å; L435-F442 HydrophobicContact CD2-CZ 3.82Å; L435-F442 HydrophobicContact CG-CE2 4.19Å; L435-F442 HydrophobicContact CG-CZ 4.34Å
436	I	91.7	Very high	88.9	Confident	37 Å²	37	54.3 Å²	54.3	19%	0.19	28%	0.275	C	S	.	.	G	3₁₀ helix	trans	-66.5	-33.7	178.2	-59.4	161.4	0	0	0	111.5	P359 L361 L434 K438 S439	P359-I436 WeakPolarHBondContact O-CD1 2.92Å; L361-I436 HydrophobicContact CB-CG1 4Å; L361-I436 HydrophobicContact CD1-CG1 3.99Å; L434-I436 PolarHBondContact O-N 3.35Å; L434-I436 VanDerWaalsContact O-N 3.12Å; I436-K438 PolarHBondContact O-N 3.06Å; I436-S439 WeakPolarHBondContact O-CB 3.44Å; I436-S439 PolarHBondContact O-N 2.98Å; I436-S439 VanDerWaalsContact O-N 3.17Å
437	L	89.9	Confident	88.5	Confident	151 Å²	151	53.5 Å²	53.5	79%	0.791	27%	0.27	S	S	*	.	G	3₁₀ helix	trans	-61.8	-25	179.1	-62.8	174.9	0	0	0	112	L434 L435	L434-L437 HydrophobicContact CD2-CD1 4.26Å; L434-L437 WeakPolarHBondContact O-CB 3.46Å; L434-L437 PolarHBondContact O-N 3.2Å; L434-L437 VanDerWaalsContact O-N 3.12Å; L435-L437 VanDerWaalsContact C-N 3.29Å; L435-L437 PolarHBondContact O-N 3.09Å
438	K	88.2	Confident	88.1	Confident	105 Å²	105	54.5 Å²	54.5	46%	0.457	28%	0.275	S	S	.	.	G	3₁₀ helix	trans	-121.6	48.2	175	-162	-179.2	177.6	179.7	0	110.8	F41 L435 I436 E440 S441	F41-K438 VanDerWaalsContact CE2-NZ 3.27Å; L435-K438 CarbonylContact O-C 3.53Å; L435-K438 PolarHBondContact O-N 3.29Å; I436-K438 PolarHBondContact O-N 3.06Å; K438-E440 PolarHBondContact O-N 3.26Å; K438-E440 VanDerWaalsContact O-N 3.13Å; K438-S441 PolarHBondContact O-N 3.39Å; K438-S441 PolarHBondContact O-OG 3.26Å; K438-S441 VanDerWaalsContact O-OG 3.08Å
439	S	87.4	Confident	87.7	Confident	36 Å²	36	57.6 Å²	57.6	25%	0.252	29%	0.29	S	S	.	.	T	Hydrogen-bonded Turn	trans	-58.9	-24.4	-177.7	57.4	0	0	0	0	114	L435 I436 S441 F442 M443	L435-S439 PolarHBondContact O-N 3.01Å; I436-S439 WeakPolarHBondContact O-CB 3.44Å; I436-S439 PolarHBondContact O-N 2.98Å; I436-S439 VanDerWaalsContact O-N 3.17Å; S439-S441 PolarHBondContact O-N 3.29Å; S439-F442 PolarHBondContact O-N 3.39Å; S439-M443 WeakPolarHBondContact O-CG 3.45Å; S439-M443 PolarHBondContact O-N 3.26Å
440	E	85.3	Confident	87.2	Confident	132 Å²	132	56.7 Å²	56.7	62%	0.617	29%	0.291	S	S	*	.	H	α-helix	trans	-47.1	-38.8	176.4	-65.9	176	-177.2	0	0	113	K438 F442 M443 L444	K438-E440 PolarHBondContact O-N 3.26Å; K438-E440 VanDerWaalsContact O-N 3.13Å; E440-F442 PolarHBondContact O-N 3.21Å; E440-F442 VanDerWaalsContact O-N 3.13Å; E440-M443 PolarHBondContact O-N 2.89Å; E440-L444 PolarHBondContact O-N 3.31Å; E440-L444 VanDerWaalsContact O-N 3.11Å
441	S	80.6	Confident	86.8	Confident	7 Å²	7	55.9 Å²	55.9	5%	0.049	29%	0.287	C	S	.	.	H	α-helix	trans	-67.6	-13.8	-178.1	61.4	0	0	0	0	115	F41 M56 K438 S439	F41-S441 VanDerWaalsContact CD1-CB 3.42Å; M56-S441 VanDerWaalsContact CE-CA 3.44Å; M56-S441 VanDerWaalsContact CE-O 3.27Å; M56-S441 WeakPolarHBondContact CE-O 3.19Å; M56-S441 WeakPolarHBondContact CG-O 3.31Å; K438-S441 PolarHBondContact O-N 3.39Å; K438-S441 PolarHBondContact O-OG 3.26Å; K438-S441 VanDerWaalsContact O-OG 3.08Å; S439-S441 PolarHBondContact O-N 3.29Å
442	F	79.4	Confident	86.3	Confident	9 Å²	9	58.5 Å²	58.5	4%	0.039	30%	0.298	C	S	.	.	H	α-helix	trans	-114.2	-20.5	178	-52.7	-67.3	0	0	0	111.7	Y301 T302 I305 L361 L435 S439 E440	Y301-F442 HydrophobicContact CD1-CB 4.11Å; Y301-F442 HydrophobicContact CD1-CD1 4.31Å; Y301-F442 WeakPolarHBondContact CD1-O 3.39Å; Y301-F442 HydrophobicContact CE1-CB 4.16Å; Y301-F442 AromaticContact CE1-CD1 3.64Å; Y301-F442 HydrophobicContact CE1-CD1 3.64Å; Y301-F442 HydrophobicContact CE1-CG 4.4Å; T302-F442 HydrophobicContact CG2-CB 3.51Å; I305-F442 HydrophobicContact CD1-CD1 3.26Å; I305-F442 HydrophobicContact CD1-CE1 3.32Å; I305-F442 HydrophobicContact CD1-CG 4.3Å; I305-F442 HydrophobicContact CD1-CZ 4.38Å; L361-F442 HydrophobicContact CD1-CD2 4.36Å; L435-F442 HydrophobicContact CB-CE2 3.95Å; L435-F442 HydrophobicContact CD1-CE2 4.19Å; L435-F442 HydrophobicContact CD1-CZ 4Å; L435-F442 HydrophobicContact CD2-CE2 3.83Å; L435-F442 HydrophobicContact CD2-CZ 3.82Å; L435-F442 HydrophobicContact CG-CE2 4.19Å; L435-F442 HydrophobicContact CG-CZ 4.34Å; S439-F442 PolarHBondContact O-N 3.39Å; E440-F442 PolarHBondContact O-N 3.21Å; E440-F442 VanDerWaalsContact O-N 3.13Å
443	M	82.8	Confident	85.8	Confident	12 Å²	12	62.6 Å²	62.6	6%	0.059	32%	0.319	C	S	.	.	H	α-helix	trans	-86	-34.3	-178.5	-64.9	-42.8	-53.7	0	0	114	Y294 C298 T302 L364 Y368 S439 E440	Y294-M443 PolarHBondContact OH-O 3.07Å; C298-M443 HydrophobicContact CB-CE 3.65Å; C298-M443 PolarHBondContact SG-O 2.72Å; T302-M443 HydrophobicContact CG2-SD 3.35Å; T302-M443 WeakPolarHBondContact CG2-SD 3.13Å; L364-M443 HydrophobicContact CD2-CE 4.28Å; L364-M443 HydrophobicContact CD2-CG 4.24Å; L364-M443 HydrophobicContact CD2-SD 3.24Å; L364-M443 WeakPolarHBondContact CD2-SD 3.39Å; Y368-M443 HydrophobicContact CD1-CE 3.32Å; Y368-M443 HydrophobicContact CD2-CE 4.09Å; Y368-M443 HydrophobicContact CE1-CE 2.91Å; Y368-M443 HydrophobicContact CE1-SD 4.42Å; Y368-M443 HydrophobicContact CE2-CE 3.73Å; Y368-M443 HydrophobicContact CE2-SD 4.37Å; Y368-M443 HydrophobicContact CG-CE 3.91Å; S439-M443 WeakPolarHBondContact O-CG 3.45Å; S439-M443 PolarHBondContact O-N 3.26Å; E440-M443 PolarHBondContact O-N 2.89Å
444	L	80.6	Confident	85.2	Confident	89 Å²	89	65.2 Å²	65.2	47%	0.466	33%	0.332	S	S	.	.			trans	-108.5	49	-168.6	-61.2	177.8	0	0	0	112.5	N43 Y294 E440	N43-L444 PolarHBondContact ND2-O 3.17Å; N43-L444 VanDerWaalsContact ND2-O 3.15Å; N43-L444 PolarHBondContact OD1-O 3.38Å; Y294-L444 WeakPolarHBondContact OH-CD2 3.33Å; E440-L444 PolarHBondContact O-N 3.31Å; E440-L444 VanDerWaalsContact O-N 3.11Å
445	W	81.2	Confident	84.6	Confident	12 Å²	12	62.5 Å²	62.5	5%	0.045	32%	0.317	C	S	.	.			trans	-88.9	-20.6	-174	74	-24.4	0	0	0	116.1	M56 L57 L232 L297 C298 Y301	M56-W445 HydrophobicContact CB-CB 4.48Å; M56-W445 HydrophobicContact CG-CB 4.24Å; M56-W445 WeakPolarHBondContact SD-CA 3.5Å; M56-W445 HydrophobicContact SD-CB 3.51Å; M56-W445 VanDerWaalsContact SD-CB 3.51Å; L57-W445 HydrophobicContact CB-CE3 4.3Å; L57-W445 HydrophobicContact CD1-CE3 4.03Å; L57-W445 HydrophobicContact CD1-CH2 4.49Å; L57-W445 HydrophobicContact CD1-CZ3 4Å; L57-W445 HydrophobicContact CD2-CE3 3.35Å; L57-W445 HydrophobicContact CD2-CH2 3.88Å; L57-W445 HydrophobicContact CD2-CZ3 2.94Å; L57-W445 HydrophobicContact CG-CD2 4.05Å; L57-W445 HydrophobicContact CG-CE3 3.2Å; L57-W445 HydrophobicContact CG-CH2 4.27Å; L57-W445 HydrophobicContact CG-CZ3 3.34Å; L232-W445 HydrophobicContact CD1-CH2 3.3Å; L232-W445 HydrophobicContact CD1-CZ2 4.41Å; L232-W445 HydrophobicContact CD1-CZ3 3.79Å; L232-W445 HydrophobicContact CD2-CH2 3.31Å; L232-W445 HydrophobicContact CD2-CZ2 3.62Å; L232-W445 HydrophobicContact CD2-CZ3 4.48Å; L232-W445 HydrophobicContact CG-CH2 3.85Å; L297-W445 HydrophobicContact CB-CZ2 3.89Å; L297-W445 WeakPolarHBondContact O-CZ2 3.34Å; C298-W445 PolarHBondContact SG-NE1 3.11Å; C298-W445 VanDerWaalsContact SG-NE1 3.38Å; Y301-W445 HydrophobicContact CD1-CD2 4.16Å; Y301-W445 AromaticContact CD1-CE3 3.44Å; Y301-W445 HydrophobicContact CD1-CE3 3.44Å; Y301-W445 VanDerWaalsContact CD1-CE3 3.44Å; Y301-W445 AromaticContact CD1-CZ3 3.88Å; Y301-W445 HydrophobicContact CD1-CZ3 3.88Å; Y301-W445 AromaticContact CD2-CE3 3.67Å; Y301-W445 HydrophobicContact CD2-CE3 3.67Å; Y301-W445 HydrophobicContact CD2-CH2 4.32Å; Y301-W445 AromaticContact CD2-CZ3 3.29Å; Y301-W445 HydrophobicContact CD2-CZ3 3.29Å; Y301-W445 AromaticContact CE1-CE3 3.93Å; Y301-W445 HydrophobicContact CE1-CE3 3.93Å; Y301-W445 HydrophobicContact CE2-CE3 4.12Å; Y301-W445 HydrophobicContact CE2-CZ3 4.04Å; Y301-W445 HydrophobicContact CG-CD2 4.22Å; Y301-W445 AromaticContact CG-CE3 3.28Å; Y301-W445 HydrophobicContact CG-CE3 3.28Å; Y301-W445 HydrophobicContact CG-CH2 4.07Å; Y301-W445 AromaticContact CG-CZ3 3.18Å; Y301-W445 HydrophobicContact CG-CZ3 3.18Å
446	L	77.6	Confident	84.1	Confident	117 Å²	117	64.3 Å²	64.3	61%	0.613	33%	0.325	S	S	*	.			trans	-101.8	0	172.5	-72.9	163	0	0	0	105	N43 Y294 L297	N43-L446 PolarHBondContact ND2-O 3.31Å; Y294-L446 HydrophobicContact CD2-CB 4.22Å; Y294-L446 HydrophobicContact CD2-CD1 4.17Å; Y294-L446 HydrophobicContact CE2-CB 3.89Å; L297-L446 HydrophobicContact CB-CD1 3.81Å; L297-L446 HydrophobicContact CD1-CD1 3.59Å; L297-L446 HydrophobicContact CG-CD1 4.35Å

Retrieved 446 of 446 residues in 925 ms (Link to these results)

U.S. Privacy Notice - Disclaimer / Registrations / Copyright Statement - Linking Policy - Notice of Privacy Practices (HIPAA) - Notice of Non‑Discrimination
© Copyright 2026 St. Jude Children's Research Hospital, a not-for-profit, section 501(c)(3).