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NADH-ubiquinone oxidoreductase chain 4

Core subunit of the mitochondrial membrane respiratory chain NADH dehydrogenase (Complex I) that is believed to belong to the minimal assembly required for catalysis. Complex I functions in the transfer of electrons from NADH to the respiratory chain. The immediate electron acceptor for the enzyme is believed to be ubiquinone (By similarity).

AlphaFold DB , UniProt , Accession P18931, Species DROME (Drosophila melanogaster, Fruit fly), Gene mt:ND4, Length 446 aa.

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(Predicted Aligned Error values between residue pairs)

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Site	Residue	pLDDT	pLDDT confidence	pLDDT₁₀	pLDDT10 confidence	SASA	SASA [Å²]	SASA₁₀	SASA10 [Å²]	RSA	RSA unformatted	RSA₁₀	RSA10 unformatted	Surface	Surface10 (not used)	Disorder (not used)	Disorder	Sec. str.	Secondary structure	Isomer	Phi (φ)	Psi (ψ)	Omega (ω)	Chi 1 (χ₁)	Chi 2 (χ₂)	Chi 3 (χ₃)	Chi 4 (χ₄)	Chi 5 (χ₅)	Tau (τ)	Contacts (colored by PAE)	Contact details
1	M	85.2	Confident	91.6	Very high	12 Å²	12	60.8 Å²	60.8	6%	0.059	28%	0.28	C	S	.	.				0	-50.3	0	-68	-48.2	-79.2	0	0	116.7	K3 I4 I5 F35 E47 L52 C54 I62 I101	M1-K3 PolarHBondContact O-N 3.34Å; M1-K3 VanDerWaalsContact O-N 3.1Å; M1-I4 HydrophobicContact CE-CD1 4.3Å; M1-I4 PolarHBondContact O-N 3.5Å; M1-I4 HydrophobicContact SD-CD1 3.91Å; M1-I5 PolarHBondContact O-N 3.47Å; M1-F35 HydrophobicContact SD-CE2 4.3Å; M1-E47 PolarHBondContact N-OE2 3.49Å; M1-L52 HydrophobicContact CB-CB 4.21Å; M1-L52 HydrophobicContact CB-CD1 4.46Å; M1-C54 VanDerWaalsContact CE-SG 3.54Å; M1-C54 VanDerWaalsContact CG-SG 3.5Å; M1-C54 HydrophobicContact SD-CB 4.44Å; M1-C54 PolarHBondContact SD-SG 2.94Å; M1-I62 HydrophobicContact CE-CD1 3.71Å; M1-I101 HydrophobicContact CE-CG2 3.73Å
2	L	87.7	Confident	91.7	Very high	56 Å²	56	59.8 Å²	59.8	29%	0.293	28%	0.277	S	S	.	.	H	α-helix	trans	-53.4	-35.5	-176.7	-72.8	167.8	0	0	0	114.6	I4 I5 F6 S49 Y50 L52	L2-I4 VanDerWaalsContact C-N 3.27Å; L2-I4 PolarHBondContact O-N 3.12Å; L2-I5 PolarHBondContact O-N 3.21Å; L2-F6 HydrophobicContact CB-CD2 4.22Å; L2-F6 HydrophobicContact CB-CE2 4.16Å; L2-F6 HydrophobicContact CD2-CE2 4.46Å; L2-F6 WeakPolarHBondContact O-CD2 3.37Å; L2-F6 PolarHBondContact O-N 3.25Å; L2-S49 WeakPolarHBondContact CG-OG 3.16Å; L2-Y50 HydrophobicContact CD1-CD2 4.23Å; L2-Y50 HydrophobicContact CD1-CE2 4.1Å; L2-L52 HydrophobicContact CD2-CD1 4.13Å
3	K	90.3	Very high	91.7	Very high	175 Å²	175	61.1 Å²	61.1	76%	0.761	29%	0.294	S	S	*	.	H	α-helix	trans	-53.5	-41.7	176.4	-63.4	179.4	-177.7	175.5	0	112.7	M1 F7	M1-K3 PolarHBondContact O-N 3.34Å; M1-K3 VanDerWaalsContact O-N 3.1Å; K3-F7 PolarHBondContact O-N 3.07Å; K3-F7 VanDerWaalsContact O-N 3.12Å
4	I	90.5	Very high	91.6	Very high	18 Å²	18	63.3 Å²	63.3	9%	0.092	30%	0.302	C	S	.	.	H	α-helix	trans	-71.7	-43.6	-179.5	-58.4	167	0	0	0	110.3	M1 L2 F7 L8 I31 F35 I101	M1-I4 HydrophobicContact CE-CD1 4.3Å; M1-I4 PolarHBondContact O-N 3.5Å; M1-I4 HydrophobicContact SD-CD1 3.91Å; L2-I4 VanDerWaalsContact C-N 3.27Å; L2-I4 PolarHBondContact O-N 3.12Å; I4-F7 WeakPolarHBondContact O-CB 3.49Å; I4-F7 PolarHBondContact O-N 3.36Å; I4-L8 WeakPolarHBondContact O-CG 3.27Å; I4-L8 PolarHBondContact O-N 3.44Å; I4-I31 HydrophobicContact CG2-CG2 3.99Å; I4-F35 HydrophobicContact CD1-CD2 3.26Å; I4-F35 HydrophobicContact CD1-CE2 3.53Å; I4-F35 HydrophobicContact CD1-CG 4.28Å; I4-F35 HydrophobicContact CG1-CD2 4.47Å; I4-I101 HydrophobicContact CG2-CD1 3.82Å
5	I	92.2	Very high	91.6	Very high	20 Å²	20	59.1 Å²	59.1	10%	0.103	28%	0.282	C	S	.	.	H	α-helix	trans	-63.2	-45.6	179.7	-63.7	166.3	0	0	0	110.3	M1 L2 F7 L8 L9 L52 L102	M1-I5 PolarHBondContact O-N 3.47Å; L2-I5 PolarHBondContact O-N 3.21Å; I5-F7 VanDerWaalsContact C-N 3.34Å; I5-F7 PolarHBondContact O-N 3.07Å; I5-L8 PolarHBondContact O-N 2.94Å; I5-L9 HydrophobicContact CG2-CD1 4.14Å; I5-L9 WeakPolarHBondContact O-CG 3.34Å; I5-L9 PolarHBondContact O-N 3.08Å; I5-L52 HydrophobicContact CD1-CD1 3.33Å; I5-L52 HydrophobicContact CD1-CD2 4.32Å; I5-L52 HydrophobicContact CD1-CG 4.48Å; I5-L102 HydrophobicContact CD1-CD2 3.72Å; I5-L102 HydrophobicContact CG1-CD2 4.43Å
6	F	92.6	Very high	91.5	Very high	107 Å²	107	62.2 Å²	62.2	47%	0.469	29%	0.294	S	S	.	.	H	α-helix	trans	-60.7	-43.5	175.8	-80.2	-59.6	0	0	0	111.9	L2 L8 L9 F10	L2-F6 HydrophobicContact CB-CD2 4.22Å; L2-F6 HydrophobicContact CB-CE2 4.16Å; L2-F6 HydrophobicContact CD2-CE2 4.46Å; L2-F6 WeakPolarHBondContact O-CD2 3.37Å; L2-F6 PolarHBondContact O-N 3.25Å; F6-L8 VanDerWaalsContact C-N 3.31Å; F6-L8 PolarHBondContact O-N 3.04Å; F6-L9 HydrophobicContact CD1-CD1 4.4Å; F6-L9 PolarHBondContact O-N 3.17Å; F6-F10 HydrophobicContact CB-CD2 4.47Å; F6-F10 HydrophobicContact CB-CE2 4.29Å; F6-F10 WeakPolarHBondContact O-CD2 3.42Å; F6-F10 PolarHBondContact O-N 2.9Å
7	F	93.7	Very high	91.4	Very high	56 Å²	56	63.6 Å²	63.6	25%	0.246	30%	0.303	C	S	.	.	H	α-helix	trans	-56.8	-45.8	175.5	-171.1	-76.5	0	0	0	111.7	K3 I4 I5 L9 F10 L11 M27 F30 I31	K3-F7 PolarHBondContact O-N 3.07Å; K3-F7 VanDerWaalsContact O-N 3.12Å; I4-F7 WeakPolarHBondContact O-CB 3.49Å; I4-F7 PolarHBondContact O-N 3.36Å; I5-F7 VanDerWaalsContact C-N 3.34Å; I5-F7 PolarHBondContact O-N 3.07Å; F7-L9 PolarHBondContact O-N 3.2Å; F7-F10 PolarHBondContact O-N 3.44Å; F7-L11 HydrophobicContact CD1-CD1 3.95Å; F7-L11 HydrophobicContact CD1-CG 4Å; F7-L11 HydrophobicContact CE1-CD1 3.64Å; F7-L11 HydrophobicContact CE1-CD2 3.99Å; F7-L11 HydrophobicContact CE1-CG 3.76Å; F7-L11 PolarHBondContact O-N 3.2Å; F7-L11 VanDerWaalsContact O-N 3.11Å; F7-M27 HydrophobicContact CE1-CB 4.2Å; F7-M27 HydrophobicContact CZ-CB 4.16Å; F7-M27 HydrophobicContact CZ-SD 4.08Å; F7-F30 HydrophobicContact CE2-CD1 4.39Å; F7-F30 HydrophobicContact CZ-CD1 4.37Å; F7-I31 HydrophobicContact CD1-CD1 3.1Å; F7-I31 HydrophobicContact CD1-CG1 3.17Å; F7-I31 HydrophobicContact CE1-CD1 3.25Å; F7-I31 HydrophobicContact CE1-CG1 3.09Å; F7-I31 HydrophobicContact CE2-CG1 4.46Å; F7-I31 HydrophobicContact CG-CD1 4.16Å; F7-I31 HydrophobicContact CG-CG1 3.92Å; F7-I31 HydrophobicContact CZ-CD1 4.37Å; F7-I31 HydrophobicContact CZ-CG1 3.79Å
8	L	93.6	Very high	90.7	Very high	1 Å²	1	66.8 Å²	66.8	1%	0.005	32%	0.322	C	S	.	.	H	α-helix	trans	-64.1	-39.3	177.9	-70.1	-179.8	0	0	0	113.1	I4 I5 F6 F10 L11 M28 I31 L97 L98 I101	I4-L8 WeakPolarHBondContact O-CG 3.27Å; I4-L8 PolarHBondContact O-N 3.44Å; I5-L8 PolarHBondContact O-N 2.94Å; F6-L8 VanDerWaalsContact C-N 3.31Å; F6-L8 PolarHBondContact O-N 3.04Å; L8-F10 VanDerWaalsContact C-N 3.32Å; L8-F10 PolarHBondContact O-N 3.39Å; L8-L11 HydrophobicContact CD2-CD1 4.18Å; L8-L11 WeakPolarHBondContact O-CB 3.19Å; L8-L11 PolarHBondContact O-N 2.64Å; L8-L11 VanDerWaalsContact O-N 3.14Å; L8-M28 HydrophobicContact CD2-SD 3.91Å; L8-I31 HydrophobicContact CD2-CD1 3.47Å; L8-I31 VanDerWaalsContact CD2-CD1 3.47Å; L8-I31 HydrophobicContact CG-CD1 4.27Å; L8-L97 HydrophobicContact CD1-CD2 3.84Å; L8-L97 HydrophobicContact CD1-CG 3.93Å; L8-L97 HydrophobicContact CD2-CD2 3.45Å; L8-L97 VanDerWaalsContact CD2-CD2 3.45Å; L8-L97 HydrophobicContact CD2-CG 4.38Å; L8-L97 HydrophobicContact CG-CD2 4.32Å; L8-L98 HydrophobicContact CB-CD1 4.47Å; L8-L98 HydrophobicContact CD1-CB 4.46Å; L8-I101 HydrophobicContact CD1-CD1 3.47Å; L8-I101 VanDerWaalsContact CD1-CD1 3.47Å
9	L	94.2	Very high	90.3	Very high	77 Å²	77	70.3 Å²	70.3	40%	0.403	34%	0.343	S	S	.	.	H	α-helix	trans	-62	-40.8	174.8	-71.3	170.3	0	0	0	111.4	I5 F6 F7 L11 I12 L98	I5-L9 HydrophobicContact CG2-CD1 4.14Å; I5-L9 WeakPolarHBondContact O-CG 3.34Å; I5-L9 PolarHBondContact O-N 3.08Å; F6-L9 HydrophobicContact CD1-CD1 4.4Å; F6-L9 PolarHBondContact O-N 3.17Å; F7-L9 PolarHBondContact O-N 3.2Å; L9-L11 PolarHBondContact O-N 3.1Å; L9-I12 HydrophobicContact CD2-CD1 4.04Å; L9-I12 WeakPolarHBondContact O-CB 2.95Å; L9-I12 PolarHBondContact O-N 3.42Å; L9-L98 HydrophobicContact CD2-CD1 3.65Å; L9-L98 HydrophobicContact CG-CD1 3.98Å
10	F	93.6	Very high	90.2	Very high	142 Å²	142	69.5 Å²	69.5	62%	0.623	34%	0.339	S	S	*	.	H	α-helix	trans	-71.3	-14.6	175.9	-71.4	-60.3	0	0	0	114.1	F6 F7 L8 P13 F14	F6-F10 HydrophobicContact CB-CD2 4.47Å; F6-F10 HydrophobicContact CB-CE2 4.29Å; F6-F10 WeakPolarHBondContact O-CD2 3.42Å; F6-F10 PolarHBondContact O-N 2.9Å; F7-F10 PolarHBondContact O-N 3.44Å; L8-F10 VanDerWaalsContact C-N 3.32Å; L8-F10 PolarHBondContact O-N 3.39Å; F10-P13 WeakPolarHBondContact O-CD 3.5Å; F10-F14 VanDerWaalsContact O-CD2 3.3Å; F10-F14 WeakPolarHBondContact O-CD2 3.43Å
11	L	93.6	Very high	90.3	Very high	5 Å²	5	66.5 Å²	66.5	3%	0.026	32%	0.324	C	S	.	.	H	α-helix	trans	-77.7	-19.8	171.4	-73.7	-179.2	0	0	0	113.9	F7 L8 L9 F14 M27 M28 I31 I94	F7-L11 HydrophobicContact CD1-CD1 3.95Å; F7-L11 HydrophobicContact CD1-CG 4Å; F7-L11 HydrophobicContact CE1-CD1 3.64Å; F7-L11 HydrophobicContact CE1-CD2 3.99Å; F7-L11 HydrophobicContact CE1-CG 3.76Å; F7-L11 PolarHBondContact O-N 3.2Å; F7-L11 VanDerWaalsContact O-N 3.11Å; L8-L11 HydrophobicContact CD2-CD1 4.18Å; L8-L11 WeakPolarHBondContact O-CB 3.19Å; L8-L11 PolarHBondContact O-N 2.64Å; L8-L11 VanDerWaalsContact O-N 3.14Å; L9-L11 PolarHBondContact O-N 3.1Å; L11-F14 HydrophobicContact CD2-CD2 4.36Å; L11-F14 PolarHBondContact O-N 3.06Å; L11-M27 HydrophobicContact CD1-CB 4.29Å; L11-M27 HydrophobicContact CD2-CB 3.56Å; L11-M27 HydrophobicContact CD2-CG 3.95Å; L11-M28 HydrophobicContact CD1-CG 4.2Å; L11-M28 HydrophobicContact CD1-SD 3.81Å; L11-I31 HydrophobicContact CD1-CD1 4.02Å; L11-I94 HydrophobicContact CB-CD1 3.73Å
12	I	93.8	Very high	90.6	Very high	48 Å²	48	70.5 Å²	70.5	25%	0.246	34%	0.338	C	S	.	.	T	Hydrogen-bonded Turn	trans	-60.2	-47.3	-177.1	-61	169.6	0	0	0	111.8	L9 F14 C15 F16 L91 I94	L9-I12 HydrophobicContact CD2-CD1 4.04Å; L9-I12 WeakPolarHBondContact O-CB 2.95Å; L9-I12 PolarHBondContact O-N 3.42Å; I12-F14 VanDerWaalsContact C-N 3.28Å; I12-F14 PolarHBondContact O-N 2.99Å; I12-C15 VanDerWaalsContact O-CB 3.32Å; I12-C15 WeakPolarHBondContact O-CB 3.43Å; I12-C15 PolarHBondContact O-N 3.21Å; I12-C15 VanDerWaalsContact O-N 3.13Å; I12-F16 HydrophobicContact CG2-CE2 4.27Å; I12-L91 HydrophobicContact CG2-CD1 4.42Å; I12-I94 HydrophobicContact CG1-CG2 3.96Å
13	P	91.9	Very high	90.9	Very high	77 Å²	77	71.3 Å²	71.3	50%	0.5	34%	0.342	S	S	.	.	G	3₁₀ helix	trans	-57.7	-37	176.1	-26.1	34.9	0	0	0	114	F10 C15 F16	F10-P13 WeakPolarHBondContact O-CD 3.5Å; P13-C15 PolarHBondContact O-N 3.35Å; P13-F16 PolarHBondContact O-N 2.62Å
14	F	90.2	Very high	91.1	Very high	92 Å²	92	63 Å²	63	40%	0.404	31%	0.306	S	S	.	.	G	3₁₀ helix	trans	-64	-23.9	179.7	-71.8	-76.4	0	0	0	113.1	F10 L11 I12 F16 I17 M20 V24	F10-F14 VanDerWaalsContact O-CD2 3.3Å; F10-F14 WeakPolarHBondContact O-CD2 3.43Å; L11-F14 HydrophobicContact CD2-CD2 4.36Å; L11-F14 PolarHBondContact O-N 3.06Å; I12-F14 VanDerWaalsContact C-N 3.28Å; I12-F14 PolarHBondContact O-N 2.99Å; F14-F16 PolarHBondContact O-N 3.23Å; F14-I17 HydrophobicContact CD1-CD1 3.96Å; F14-I17 HydrophobicContact CE1-CD1 4.5Å; F14-I17 PolarHBondContact O-N 2.95Å; F14-M20 HydrophobicContact CD1-CE 4.28Å; F14-V24 HydrophobicContact CB-CG2 4.24Å
15	C	91	Very high	91.3	Very high	0 Å²	0	62.9 Å²	62.9	0%	0	31%	0.305	C	S	.	.	G	3₁₀ helix	trans	-66.2	-25.4	177.3	-65.7	0	0	0	0	113.6	I12 P13 N87 L90 I94	I12-C15 VanDerWaalsContact O-CB 3.32Å; I12-C15 WeakPolarHBondContact O-CB 3.43Å; I12-C15 PolarHBondContact O-N 3.21Å; I12-C15 VanDerWaalsContact O-N 3.13Å; P13-C15 PolarHBondContact O-N 3.35Å; C15-N87 PolarHBondContact O-OD1 2.93Å; C15-L90 HydrophobicContact CB-CB 4.04Å; C15-I94 WeakPolarHBondContact SG-CD1 3.37Å
16	F	90.2	Very high	91.4	Very high	109 Å²	109	66.6 Å²	66.6	48%	0.478	32%	0.324	S	S	.	.	G	3₁₀ helix	trans	-90.7	-12.7	-177.8	-65.4	-72.6	0	0	0	113.2	I12 P13 F14 L91	I12-F16 HydrophobicContact CG2-CE2 4.27Å; P13-F16 PolarHBondContact O-N 2.62Å; F14-F16 PolarHBondContact O-N 3.23Å; F16-L91 HydrophobicContact CE1-CD1 4.21Å; F16-L91 HydrophobicContact CE2-CD1 3.76Å; F16-L91 HydrophobicContact CZ-CD1 3.3Å
17	I	89.2	Confident	91.5	Very high	86 Å²	86	64.1 Å²	64.1	44%	0.441	31%	0.314	S	S	.	.	S	Bend	trans	-76.2	129.2	178.5	-57.3	174.6	0	0	0	109.1	F14 N19 M20	F14-I17 HydrophobicContact CD1-CD1 3.96Å; F14-I17 HydrophobicContact CE1-CD1 4.5Å; F14-I17 PolarHBondContact O-N 2.95Å; I17-N19 PolarHBondContact O-N 3.35Å; I17-M20 HydrophobicContact CB-CB 4.33Å; I17-M20 HydrophobicContact CB-CG 3.7Å; I17-M20 HydrophobicContact CG2-CG 3.51Å; I17-M20 PolarHBondContact O-N 3.39Å
18	N	79.4	Confident	91.5	Very high	121 Å²	121	61.5 Å²	61.5	65%	0.647	30%	0.303	S	S	*	.	T	Hydrogen-bonded Turn	trans	-57.1	138.1	179.4	-72.1	-17.3	0	0	0	111.4	M20	N18-M20 VanDerWaalsContact C-N 3.27Å; N18-M20 PolarHBondContact O-N 2.71Å
19	N	82.4	Confident	91.5	Very high	134 Å²	134	62.6 Å²	62.6	72%	0.717	31%	0.308	S	S	*	.	T	Hydrogen-bonded Turn	trans	68.1	7	177.9	-58.7	-18.2	0	0	0	117.2	I17 Y21	I17-N19 PolarHBondContact O-N 3.35Å; N19-Y21 VanDerWaalsContact C-N 3.31Å; N19-Y21 PolarHBondContact O-N 3.28Å
20	M	89.2	Confident	91.6	Very high	54 Å²	54	64.4 Å²	64.4	27%	0.266	31%	0.313	S	S	.	.			trans	-86.6	15.1	-177.4	-64	-62.3	-85.2	0	0	115.4	F14 I17 N18 W22 M23 V24	F14-M20 HydrophobicContact CD1-CE 4.28Å; I17-M20 HydrophobicContact CB-CB 4.33Å; I17-M20 HydrophobicContact CB-CG 3.7Å; I17-M20 HydrophobicContact CG2-CG 3.51Å; I17-M20 PolarHBondContact O-N 3.39Å; N18-M20 VanDerWaalsContact C-N 3.27Å; N18-M20 PolarHBondContact O-N 2.71Å; M20-W22 PolarHBondContact O-N 3.39Å; M20-M23 HydrophobicContact CB-CB 4.41Å; M20-M23 HydrophobicContact CE-CB 3.76Å; M20-M23 HydrophobicContact CE-CG 3.57Å; M20-M23 PolarHBondContact O-N 2.81Å; M20-M23 VanDerWaalsContact O-N 3.14Å; M20-M23 HydrophobicContact SD-CB 4.2Å; M20-V24 PolarHBondContact O-N 3.5Å; M20-V24 VanDerWaalsContact O-N 3.08Å
21	Y	91.3	Very high	91.6	Very high	6 Å²	6	57.9 Å²	57.9	2%	0.024	28%	0.284	C	S	.	.	H	α-helix	trans	-53.7	-51	-178	-177.4	-85.6	0	0	0	112.9	N19 M23 V24 Q25 L73 S76 N80 F89 L90	N19-Y21 VanDerWaalsContact C-N 3.31Å; N19-Y21 PolarHBondContact O-N 3.28Å; Y21-M23 VanDerWaalsContact C-N 3.33Å; Y21-M23 PolarHBondContact O-N 2.92Å; Y21-V24 PolarHBondContact O-N 3.41Å; Y21-Q25 PolarHBondContact O-N 3.5Å; Y21-L73 WeakPolarHBondContact CE1-O 2.92Å; Y21-L73 HydrophobicContact CE2-CD2 4.25Å; Y21-L73 PolarHBondContact OH-O 3.21Å; Y21-S76 PolarHBondContact OH-O 3.42Å; Y21-S76 PolarHBondContact OH-OG 2.92Å; Y21-N80 HydrophobicContact CD1-CB 4.28Å; Y21-N80 HydrophobicContact CD2-CB 4.16Å; Y21-N80 HydrophobicContact CE1-CB 4.39Å; Y21-N80 HydrophobicContact CE2-CB 4.26Å; Y21-N80 HydrophobicContact CG-CB 4.19Å; Y21-F89 HydrophobicContact CE2-CD1 4.37Å; Y21-L90 HydrophobicContact CD2-CD1 3.92Å; Y21-L90 HydrophobicContact CD2-CD2 3.58Å; Y21-L90 HydrophobicContact CD2-CG 3.9Å; Y21-L90 HydrophobicContact CE2-CD2 3.66Å; Y21-L90 HydrophobicContact CE2-CG 4.23Å; Y21-L90 HydrophobicContact CG-CD2 4.37Å
22	W	92.4	Very high	91.6	Very high	96 Å²	96	57.6 Å²	57.6	36%	0.364	28%	0.283	S	S	.	.	H	α-helix	trans	-71	-29.8	-179	-59.8	115.1	0	0	0	112.6	M20 Q25 I26 L74 E77	M20-W22 PolarHBondContact O-N 3.39Å; W22-Q25 VanDerWaalsContact CZ3-OE1 3.23Å; W22-Q25 WeakPolarHBondContact O-CB 3.49Å; W22-Q25 PolarHBondContact O-N 3.26Å; W22-I26 WeakPolarHBondContact O-CG1 3.2Å; W22-I26 PolarHBondContact O-N 3Å; W22-L74 HydrophobicContact CZ3-CD2 4.25Å; W22-E77 HydrophobicContact CH2-CB 4.33Å; W22-E77 HydrophobicContact CH2-CG 4.05Å; W22-E77 HydrophobicContact CZ2-CG 4.05Å
23	M	93.5	Very high	91.6	Very high	74 Å²	74	60.2 Å²	60.2	37%	0.365	29%	0.292	S	S	.	.	H	α-helix	trans	-66.6	-43.7	177.3	-173.8	61.3	159.2	0	0	111.3	M20 Y21 Q25 I26 M27	M20-M23 HydrophobicContact CB-CB 4.41Å; M20-M23 HydrophobicContact CE-CB 3.76Å; M20-M23 HydrophobicContact CE-CG 3.57Å; M20-M23 PolarHBondContact O-N 2.81Å; M20-M23 VanDerWaalsContact O-N 3.14Å; M20-M23 HydrophobicContact SD-CB 4.2Å; Y21-M23 VanDerWaalsContact C-N 3.33Å; Y21-M23 PolarHBondContact O-N 2.92Å; M23-Q25 VanDerWaalsContact C-N 3.27Å; M23-Q25 PolarHBondContact O-N 2.68Å; M23-I26 PolarHBondContact O-N 2.61Å; M23-M27 HydrophobicContact CE-CE 3.27Å; M23-M27 WeakPolarHBondContact O-CG 3.43Å; M23-M27 PolarHBondContact O-N 2.95Å; M23-M27 HydrophobicContact SD-CE 4.05Å
24	V	94.5	Very high	91.6	Very high	1 Å²	1	59.2 Å²	59.2	1%	0.006	28%	0.282	C	S	.	.	H	α-helix	trans	-56.7	-45.3	174.5	173.2	0	0	0	0	110.3	F14 M20 Y21 I26 M27 M28 L73 L90 I94	F14-V24 HydrophobicContact CB-CG2 4.24Å; M20-V24 PolarHBondContact O-N 3.5Å; M20-V24 VanDerWaalsContact O-N 3.08Å; Y21-V24 PolarHBondContact O-N 3.41Å; V24-I26 PolarHBondContact O-N 3.28Å; V24-M27 PolarHBondContact O-N 3.32Å; V24-M28 HydrophobicContact CG1-CG 4.48Å; V24-M28 WeakPolarHBondContact O-CG 3.49Å; V24-M28 PolarHBondContact O-N 3.05Å; V24-L73 HydrophobicContact CG1-CD1 4.32Å; V24-L90 HydrophobicContact CG1-CD2 4.4Å; V24-I94 HydrophobicContact CG1-CD1 3.92Å
25	Q	94.1	Very high	91.7	Very high	14 Å²	14	55 Å²	55	7%	0.065	26%	0.263	C	S	.	.	H	α-helix	trans	-62	-45	178.2	-174.8	-158.6	-59	0	0	112.9	Y21 W22 M23 M27 M28 F29 L73 L74	Y21-Q25 PolarHBondContact O-N 3.5Å; W22-Q25 VanDerWaalsContact CZ3-OE1 3.23Å; W22-Q25 WeakPolarHBondContact O-CB 3.49Å; W22-Q25 PolarHBondContact O-N 3.26Å; M23-Q25 VanDerWaalsContact C-N 3.27Å; M23-Q25 PolarHBondContact O-N 2.68Å; Q25-M27 VanDerWaalsContact C-N 3.3Å; Q25-M27 PolarHBondContact O-N 3.4Å; Q25-M28 WeakPolarHBondContact O-CB 3.44Å; Q25-M28 PolarHBondContact O-N 2.99Å; Q25-F29 HydrophobicContact CG-CD2 4.12Å; Q25-F29 HydrophobicContact CG-CE2 3.9Å; Q25-F29 WeakPolarHBondContact O-CD2 3.48Å; Q25-F29 PolarHBondContact O-N 2.96Å; Q25-F29 VanDerWaalsContact O-N 3.08Å; Q25-L73 HydrophobicContact CB-CB 4.14Å; Q25-L73 HydrophobicContact CB-CD1 3.99Å; Q25-L73 HydrophobicContact CG-CB 3.89Å; Q25-L73 HydrophobicContact CG-CD1 4.34Å; Q25-L74 VanDerWaalsContact CD-CG 3.44Å; Q25-L74 HydrophobicContact CG-CG 4.41Å
26	I	94.2	Very high	91.7	Very high	99 Å²	99	57.6 Å²	57.6	51%	0.508	28%	0.277	S	S	.	.	H	α-helix	trans	-61.4	-42.2	178.5	-69.2	164.1	0	0	0	110.3	W22 M23 V24 M28 F29 F30	W22-I26 WeakPolarHBondContact O-CG1 3.2Å; W22-I26 PolarHBondContact O-N 3Å; M23-I26 PolarHBondContact O-N 2.61Å; V24-I26 PolarHBondContact O-N 3.28Å; I26-M28 VanDerWaalsContact C-N 3.3Å; I26-M28 PolarHBondContact O-N 2.8Å; I26-F29 PolarHBondContact O-N 3.45Å; I26-F30 PolarHBondContact O-N 3.36Å
27	M	95	Very high	91.7	Very high	55 Å²	55	59.1 Å²	59.1	27%	0.271	29%	0.29	S	S	.	.	H	α-helix	trans	-62.8	-37.6	176.6	-69.9	-63	172.1	0	0	112.3	F7 L11 M23 V24 Q25 F30 I31	F7-M27 HydrophobicContact CE1-CB 4.2Å; F7-M27 HydrophobicContact CZ-CB 4.16Å; F7-M27 HydrophobicContact CZ-SD 4.08Å; L11-M27 HydrophobicContact CD1-CB 4.29Å; L11-M27 HydrophobicContact CD2-CB 3.56Å; L11-M27 HydrophobicContact CD2-CG 3.95Å; M23-M27 HydrophobicContact CE-CE 3.27Å; M23-M27 WeakPolarHBondContact O-CG 3.43Å; M23-M27 PolarHBondContact O-N 2.95Å; M23-M27 HydrophobicContact SD-CE 4.05Å; V24-M27 PolarHBondContact O-N 3.32Å; Q25-M27 VanDerWaalsContact C-N 3.3Å; Q25-M27 PolarHBondContact O-N 3.4Å; M27-F30 WeakPolarHBondContact O-CB 3.36Å; M27-F30 PolarHBondContact O-N 2.94Å; M27-I31 WeakPolarHBondContact O-CG1 3.38Å; M27-I31 PolarHBondContact O-N 3.25Å
28	M	94.1	Very high	91.5	Very high	0 Å²	0	59.2 Å²	59.2	0%	0	29%	0.289	C	S	.	.	H	α-helix	trans	-64.3	-41.3	176	-65.3	-82.3	-74.3	0	0	112	L8 L11 V24 Q25 I26 F30 I31 S32 C69 L97	L8-M28 HydrophobicContact CD2-SD 3.91Å; L11-M28 HydrophobicContact CD1-CG 4.2Å; L11-M28 HydrophobicContact CD1-SD 3.81Å; V24-M28 HydrophobicContact CG1-CG 4.48Å; V24-M28 WeakPolarHBondContact O-CG 3.49Å; V24-M28 PolarHBondContact O-N 3.05Å; Q25-M28 WeakPolarHBondContact O-CB 3.44Å; Q25-M28 PolarHBondContact O-N 2.99Å; I26-M28 VanDerWaalsContact C-N 3.3Å; I26-M28 PolarHBondContact O-N 2.8Å; M28-F30 VanDerWaalsContact C-N 3.34Å; M28-I31 PolarHBondContact O-N 3Å; M28-I31 HydrophobicContact SD-CD1 4.3Å; M28-S32 PolarHBondContact O-N 2.95Å; M28-S32 VanDerWaalsContact O-N 3.16Å; M28-C69 HydrophobicContact CE-CB 3.92Å; M28-L97 HydrophobicContact CE-CB 4.37Å; M28-L97 HydrophobicContact CE-CD2 3.17Å; M28-L97 HydrophobicContact CE-CG 4.31Å; M28-L97 HydrophobicContact SD-CD2 3.67Å
29	F	94.7	Very high	91.5	Very high	25 Å²	25	57.2 Å²	57.2	11%	0.11	28%	0.279	C	S	.	.	H	α-helix	trans	-62.1	-41.9	171	-81.5	-66.4	0	0	0	111.7	Q25 I26 I31 S32 F33 S70 L71 L74 L427	Q25-F29 HydrophobicContact CG-CD2 4.12Å; Q25-F29 HydrophobicContact CG-CE2 3.9Å; Q25-F29 WeakPolarHBondContact O-CD2 3.48Å; Q25-F29 PolarHBondContact O-N 2.96Å; Q25-F29 VanDerWaalsContact O-N 3.08Å; I26-F29 PolarHBondContact O-N 3.45Å; F29-I31 VanDerWaalsContact C-N 3.33Å; F29-I31 PolarHBondContact O-N 2.85Å; F29-S32 WeakPolarHBondContact O-CB 3.43Å; F29-S32 PolarHBondContact O-N 3.2Å; F29-S32 PolarHBondContact O-OG 3.08Å; F29-F33 HydrophobicContact CB-CE2 4.33Å; F29-F33 WeakPolarHBondContact O-CD2 3.27Å; F29-F33 PolarHBondContact O-N 2.73Å; F29-S70 WeakPolarHBondContact CD1-OG 3.06Å; F29-S70 WeakPolarHBondContact CE1-OG 3.22Å; F29-S70 WeakPolarHBondContact CZ-OG 3.4Å; F29-L71 HydrophobicContact CZ-CD2 4.26Å; F29-L74 HydrophobicContact CE2-CD1 3.71Å; F29-L74 HydrophobicContact CE2-CG 4.28Å; F29-L74 HydrophobicContact CZ-CD1 3.64Å; F29-L427 HydrophobicContact CE1-CD1 4.09Å; F29-L427 HydrophobicContact CZ-CD1 3.86Å
30	F	94.7	Very high	91.2	Very high	115 Å²	115	52 Å²	52	50%	0.504	25%	0.251	S	S	.	.	H	α-helix	trans	-58.5	-43	177.6	-173.5	-110.2	0	0	0	112.3	F7 I26 M27 M28 S32 F33 I34	F7-F30 HydrophobicContact CE2-CD1 4.39Å; F7-F30 HydrophobicContact CZ-CD1 4.37Å; I26-F30 PolarHBondContact O-N 3.36Å; M27-F30 WeakPolarHBondContact O-CB 3.36Å; M27-F30 PolarHBondContact O-N 2.94Å; M28-F30 VanDerWaalsContact C-N 3.34Å; F30-S32 VanDerWaalsContact C-N 3.33Å; F30-S32 PolarHBondContact O-N 3.05Å; F30-F33 PolarHBondContact O-N 3.16Å; F30-I34 HydrophobicContact CD1-CD1 3.53Å; F30-I34 HydrophobicContact CD1-CG1 4.43Å; F30-I34 HydrophobicContact CE1-CD1 3.29Å; F30-I34 HydrophobicContact CE1-CG1 4.21Å; F30-I34 HydrophobicContact CG-CD1 4.31Å; F30-I34 HydrophobicContact CZ-CD1 3.86Å; F30-I34 HydrophobicContact CZ-CG1 4.35Å; F30-I34 WeakPolarHBondContact O-CG1 3.4Å; F30-I34 PolarHBondContact O-N 3.27Å
31	I	94.4	Very high	90.4	Very high	4 Å²	4	52.1 Å²	52.1	2%	0.021	25%	0.25	C	C	.	.	H	α-helix	trans	-59.3	-45.4	172.9	-56.1	164.7	0	0	0	111	I4 F7 L8 L11 M27 M28 F29 F33 I34 F35 L66	I4-I31 HydrophobicContact CG2-CG2 3.99Å; F7-I31 HydrophobicContact CD1-CD1 3.1Å; F7-I31 HydrophobicContact CD1-CG1 3.17Å; F7-I31 HydrophobicContact CE1-CD1 3.25Å; F7-I31 HydrophobicContact CE1-CG1 3.09Å; F7-I31 HydrophobicContact CE2-CG1 4.46Å; F7-I31 HydrophobicContact CG-CD1 4.16Å; F7-I31 HydrophobicContact CG-CG1 3.92Å; F7-I31 HydrophobicContact CZ-CD1 4.37Å; F7-I31 HydrophobicContact CZ-CG1 3.79Å; L8-I31 HydrophobicContact CD2-CD1 3.47Å; L8-I31 VanDerWaalsContact CD2-CD1 3.47Å; L8-I31 HydrophobicContact CG-CD1 4.27Å; L11-I31 HydrophobicContact CD1-CD1 4.02Å; M27-I31 WeakPolarHBondContact O-CG1 3.38Å; M27-I31 PolarHBondContact O-N 3.25Å; M28-I31 PolarHBondContact O-N 3Å; M28-I31 HydrophobicContact SD-CD1 4.3Å; F29-I31 VanDerWaalsContact C-N 3.33Å; F29-I31 PolarHBondContact O-N 2.85Å; I31-F33 VanDerWaalsContact C-N 3.26Å; I31-F33 PolarHBondContact O-N 3.07Å; I31-I34 PolarHBondContact O-N 2.9Å; I31-I34 VanDerWaalsContact O-N 3.14Å; I31-F35 WeakPolarHBondContact O-CB 3.37Å; I31-F35 PolarHBondContact O-N 3.33Å; I31-L66 HydrophobicContact CB-CD2 4.32Å; I31-L66 HydrophobicContact CG2-CD1 4.11Å; I31-L66 HydrophobicContact CG2-CD2 3.73Å
32	S	93.6	Very high	89.8	Confident	0 Å²	0	57.5 Å²	57.5	0%	0	28%	0.277	C	S	.	.	H	α-helix	trans	-60.3	-38.9	-178.1	74.8	0	0	0	0	111.6	M28 F29 F30 F35 L36	M28-S32 PolarHBondContact O-N 2.95Å; M28-S32 VanDerWaalsContact O-N 3.16Å; F29-S32 WeakPolarHBondContact O-CB 3.43Å; F29-S32 PolarHBondContact O-N 3.2Å; F29-S32 PolarHBondContact O-OG 3.08Å; F30-S32 VanDerWaalsContact C-N 3.33Å; F30-S32 PolarHBondContact O-N 3.05Å; S32-F35 PolarHBondContact O-N 3.03Å; S32-L36 WeakPolarHBondContact O-CG 3.4Å; S32-L36 PolarHBondContact O-N 3.11Å
33	F	93.4	Very high	89.3	Confident	103 Å²	103	56 Å²	56	45%	0.452	28%	0.276	S	S	.	.	H	α-helix	trans	-70.1	-39.3	174.2	-70.2	-63.3	0	0	0	112.6	F29 F30 I31 F35 L36 L37 W67	F29-F33 HydrophobicContact CB-CE2 4.33Å; F29-F33 WeakPolarHBondContact O-CD2 3.27Å; F29-F33 PolarHBondContact O-N 2.73Å; F30-F33 PolarHBondContact O-N 3.16Å; I31-F33 VanDerWaalsContact C-N 3.26Å; I31-F33 PolarHBondContact O-N 3.07Å; F33-F35 VanDerWaalsContact C-N 3.29Å; F33-F35 PolarHBondContact O-N 2.94Å; F33-L36 HydrophobicContact CD1-CD1 4.02Å; F33-L36 HydrophobicContact CE1-CD1 4.46Å; F33-L36 WeakPolarHBondContact O-CB 3.42Å; F33-L36 PolarHBondContact O-N 3.26Å; F33-L37 VanDerWaalsContact O-CG 3.31Å; F33-L37 WeakPolarHBondContact O-CG 3.26Å; F33-L37 PolarHBondContact O-N 2.77Å; F33-W67 HydrophobicContact CE1-CZ3 4.28Å; F33-W67 HydrophobicContact CZ-CH2 4.4Å; F33-W67 HydrophobicContact CZ-CZ3 4.19Å
34	I	92.8	Very high	88.8	Confident	56 Å²	56	61.1 Å²	61.1	29%	0.287	29%	0.292	S	S	.	.	H	α-helix	trans	-59.8	-43.4	172.5	-67.7	163.6	0	0	0	110.5	F30 I31 L37 M38	F30-I34 HydrophobicContact CD1-CD1 3.53Å; F30-I34 HydrophobicContact CD1-CG1 4.43Å; F30-I34 HydrophobicContact CE1-CD1 3.29Å; F30-I34 HydrophobicContact CE1-CG1 4.21Å; F30-I34 HydrophobicContact CG-CD1 4.31Å; F30-I34 HydrophobicContact CZ-CD1 3.86Å; F30-I34 HydrophobicContact CZ-CG1 4.35Å; F30-I34 WeakPolarHBondContact O-CG1 3.4Å; F30-I34 PolarHBondContact O-N 3.27Å; I31-I34 PolarHBondContact O-N 2.9Å; I31-I34 VanDerWaalsContact O-N 3.14Å; I34-L37 WeakPolarHBondContact O-CB 3.34Å; I34-L37 PolarHBondContact O-N 3.18Å; I34-L37 VanDerWaalsContact O-N 3.14Å; I34-M38 HydrophobicContact CG2-CE 3.95Å; I34-M38 WeakPolarHBondContact O-CG 3.01Å; I34-M38 PolarHBondContact O-N 3.45Å; I34-M38 VanDerWaalsContact O-N 3.12Å
35	F	92.4	Very high	88.2	Confident	2 Å²	2	62.1 Å²	62.1	1%	0.009	30%	0.296	C	S	.	.	H	α-helix	trans	-67.4	-37.9	-180	-168.5	-112.1	0	0	0	112.5	M1 I4 I31 S32 F33 L37 M38 Y59 I62 L63 L66	M1-F35 HydrophobicContact SD-CE2 4.3Å; I4-F35 HydrophobicContact CD1-CD2 3.26Å; I4-F35 HydrophobicContact CD1-CE2 3.53Å; I4-F35 HydrophobicContact CD1-CG 4.28Å; I4-F35 HydrophobicContact CG1-CD2 4.47Å; I31-F35 WeakPolarHBondContact O-CB 3.37Å; I31-F35 PolarHBondContact O-N 3.33Å; S32-F35 PolarHBondContact O-N 3.03Å; F33-F35 VanDerWaalsContact C-N 3.29Å; F33-F35 PolarHBondContact O-N 2.94Å; F35-L37 VanDerWaalsContact C-N 3.3Å; F35-L37 PolarHBondContact O-N 3.19Å; F35-M38 PolarHBondContact O-N 3.04Å; F35-Y59 HydrophobicContact CD1-CD2 4.26Å; F35-Y59 AromaticContact CD1-CE2 3.84Å; F35-Y59 HydrophobicContact CD1-CE2 3.84Å; F35-Y59 AromaticContact CE1-CD2 3.39Å; F35-Y59 HydrophobicContact CE1-CD2 3.39Å; F35-Y59 AromaticContact CE1-CE2 3.45Å; F35-Y59 HydrophobicContact CE1-CE2 3.45Å; F35-Y59 VanDerWaalsContact CE1-CE2 3.45Å; F35-Y59 HydrophobicContact CE1-CG 4.12Å; F35-Y59 WeakPolarHBondContact CE1-O 3.25Å; F35-Y59 HydrophobicContact CE2-CD2 4.09Å; F35-Y59 HydrophobicContact CE2-CE2 4.21Å; F35-Y59 HydrophobicContact CG-CE2 4.38Å; F35-Y59 AromaticContact CZ-CD2 3.31Å; F35-Y59 HydrophobicContact CZ-CD2 3.31Å; F35-Y59 AromaticContact CZ-CE2 3.68Å; F35-Y59 HydrophobicContact CZ-CE2 3.68Å; F35-Y59 HydrophobicContact CZ-CG 4.22Å; F35-Y59 WeakPolarHBondContact O-CE2 3.48Å; F35-Y59 PolarHBondContact O-OH 3.34Å; F35-Y59 VanDerWaalsContact O-OH 3.14Å; F35-I62 HydrophobicContact CD1-CG2 4.22Å; F35-I62 HydrophobicContact CE1-CB 3.88Å; F35-I62 HydrophobicContact CE1-CG2 3.61Å; F35-I62 HydrophobicContact CE2-CG2 4.08Å; F35-I62 HydrophobicContact CZ-CB 3.85Å; F35-I62 HydrophobicContact CZ-CD1 4.47Å; F35-I62 HydrophobicContact CZ-CG2 3.5Å; F35-L63 HydrophobicContact CD1-CB 3.95Å; F35-L63 HydrophobicContact CD1-CD1 4.08Å; F35-L63 HydrophobicContact CE1-CB 3.95Å; F35-L66 HydrophobicContact CB-CD1 3.86Å; F35-L66 HydrophobicContact CD1-CD1 4.04Å; F35-L66 HydrophobicContact CG-CD1 3.95Å
36	L	90.8	Very high	87.8	Confident	56 Å²	56	62.5 Å²	62.5	29%	0.293	30%	0.3	S	S	.	.	H	α-helix	trans	-56.8	-44.3	168.3	-77.8	167.7	0	0	0	111.3	S32 F33 M38 N39 Y59 L63	S32-L36 WeakPolarHBondContact O-CG 3.4Å; S32-L36 PolarHBondContact O-N 3.11Å; F33-L36 HydrophobicContact CD1-CD1 4.02Å; F33-L36 HydrophobicContact CE1-CD1 4.46Å; F33-L36 WeakPolarHBondContact O-CB 3.42Å; F33-L36 PolarHBondContact O-N 3.26Å; L36-M38 VanDerWaalsContact C-N 3.32Å; L36-M38 PolarHBondContact O-N 2.94Å; L36-N39 PolarHBondContact O-N 3.23Å; L36-N39 PolarHBondContact O-ND2 2.94Å; L36-N39 PolarHBondContact O-OD1 2.89Å; L36-Y59 WeakPolarHBondContact CA-OH 3.22Å; L36-Y59 PolarHBondContact O-OH 3.44Å; L36-L63 HydrophobicContact CD1-CD1 4.25Å; L36-L63 HydrophobicContact CD2-CD1 3.51Å; L36-L63 HydrophobicContact CD2-CD2 3.49Å; L36-L63 VanDerWaalsContact CD2-CD2 3.49Å; L36-L63 HydrophobicContact CD2-CG 4.13Å; L36-L63 HydrophobicContact CG-CD1 3.49Å; L36-L63 VanDerWaalsContact CG-CD1 3.49Å; L36-L63 HydrophobicContact CG-CD2 4.43Å
37	L	89.3	Confident	87.3	Confident	140 Å²	140	61.1 Å²	61.1	73%	0.733	29%	0.292	S	S	*	.	H	α-helix	trans	-66.9	-29.2	-179.5	-68.9	170.4	0	0	0	113.6	F33 I34 F35 N39	F33-L37 VanDerWaalsContact O-CG 3.31Å; F33-L37 WeakPolarHBondContact O-CG 3.26Å; F33-L37 PolarHBondContact O-N 2.77Å; I34-L37 WeakPolarHBondContact O-CB 3.34Å; I34-L37 PolarHBondContact O-N 3.18Å; I34-L37 VanDerWaalsContact O-N 3.14Å; F35-L37 VanDerWaalsContact C-N 3.3Å; F35-L37 PolarHBondContact O-N 3.19Å; L37-N39 VanDerWaalsContact C-N 3.26Å; L37-N39 PolarHBondContact O-N 3.01Å
38	M	85.7	Confident	86.8	Confident	89 Å²	89	63.6 Å²	63.6	44%	0.438	31%	0.305	S	S	.	.	H	α-helix	trans	-67.4	-23.1	178.7	-65.7	-65.9	168.5	0	0	113.4	I34 F35 L36 N40	I34-M38 HydrophobicContact CG2-CE 3.95Å; I34-M38 WeakPolarHBondContact O-CG 3.01Å; I34-M38 PolarHBondContact O-N 3.45Å; I34-M38 VanDerWaalsContact O-N 3.12Å; F35-M38 PolarHBondContact O-N 3.04Å; L36-M38 VanDerWaalsContact C-N 3.32Å; L36-M38 PolarHBondContact O-N 2.94Å; M38-N40 PolarHBondContact O-N 3.47Å; M38-N40 PolarHBondContact O-OD1 3.33Å
39	N	78.9	Confident	86.3	Confident	79 Å²	79	64.8 Å²	64.8	42%	0.422	31%	0.313	S	S	.	.			trans	38.2	62.5	170.5	-79.7	-35.5	0	0	0	115.9	L36 L37 F41	L36-N39 PolarHBondContact O-N 3.23Å; L36-N39 PolarHBondContact O-ND2 2.94Å; L36-N39 PolarHBondContact O-OD1 2.89Å; L37-N39 VanDerWaalsContact C-N 3.26Å; L37-N39 PolarHBondContact O-N 3.01Å; N39-F41 VanDerWaalsContact C-N 3.29Å; N39-F41 HydrophobicContact CB-CD2 4.06Å; N39-F41 HydrophobicContact CB-CE2 3.87Å; N39-F41 PolarHBondContact O-N 2.89Å; N39-F41 WeakPolarHBondContact OD1-CE2 3.46Å
40	N	75.1	Confident	86	Confident	24 Å²	24	73.6 Å²	73.6	13%	0.128	35%	0.347	C	S	.	.			trans	-83.5	66.8	176.3	-69.2	-28.3	0	0	0	112.3	M38 M42 S46 E47 Y59	M38-N40 PolarHBondContact O-N 3.47Å; M38-N40 PolarHBondContact O-OD1 3.33Å; N40-M42 PolarHBondContact O-N 3.47Å; N40-M42 VanDerWaalsContact O-N 3.09Å; N40-S46 WeakPolarHBondContact CB-OG 3.27Å; N40-E47 PolarHBondContact ND2-OE1 3.19Å; N40-Y59 HydrophobicContact CB-CD2 4.21Å
41	F	73.8	Confident	85.8	Confident	57 Å²	57	71.4 Å²	71.4	25%	0.25	34%	0.338	C	S	.	.			trans	-85	50.7	175.4	-59.9	-63	0	0	0	112.3	N39 M56 Y59 K438 S441	N39-F41 VanDerWaalsContact C-N 3.29Å; N39-F41 HydrophobicContact CB-CD2 4.06Å; N39-F41 HydrophobicContact CB-CE2 3.87Å; N39-F41 PolarHBondContact O-N 2.89Å; N39-F41 WeakPolarHBondContact OD1-CE2 3.46Å; F41-M56 HydrophobicContact CB-CE 4.31Å; F41-M56 HydrophobicContact CD1-CE 4.27Å; F41-Y59 HydrophobicContact CD1-CD1 4.43Å; F41-Y59 HydrophobicContact CD1-CE1 4.4Å; F41-Y59 AromaticContact CE1-CD1 3.97Å; F41-Y59 HydrophobicContact CE1-CD1 3.97Å; F41-Y59 AromaticContact CE1-CE1 3.62Å; F41-Y59 HydrophobicContact CE1-CE1 3.62Å; F41-Y59 AromaticContact CZ-CE1 3.86Å; F41-Y59 HydrophobicContact CZ-CE1 3.86Å; F41-K438 VanDerWaalsContact CE2-NZ 3.27Å; F41-S441 VanDerWaalsContact CD1-CB 3.42Å
42	M	79	Confident	85.7	Confident	119 Å²	119	71.3 Å²	71.3	59%	0.586	34%	0.337	S	S	*	.			trans	-104.9	137.9	173.6	-63.4	-62.6	-173.6	0	0	109.8	N40 Y44 M56	N40-M42 PolarHBondContact O-N 3.47Å; N40-M42 VanDerWaalsContact O-N 3.09Å; M42-Y44 PolarHBondContact O-N 3.05Å; M42-M56 PolarHBondContact O-N 2.99Å; M42-M56 VanDerWaalsContact O-N 3.14Å
43	N	81.7	Confident	85.6	Confident	64 Å²	64	71.3 Å²	71.3	34%	0.342	34%	0.337	S	S	.	.	S	Bend	trans	-69.3	-25.4	177.8	-64.6	19.7	0	0	0	111.5	L444 L446	N43-L444 PolarHBondContact ND2-O 3.17Å; N43-L444 VanDerWaalsContact ND2-O 3.15Å; N43-L444 PolarHBondContact OD1-O 3.38Å; N43-L446 PolarHBondContact ND2-O 3.31Å
44	Y	81.9	Confident	85.4	Confident	182 Å²	182	66.4 Å²	66.4	71%	0.714	32%	0.316	S	S	*	.	S	Bend	trans	-89.9	154	173.1	-45.3	-72.6	0	0	0	110.1	M42 S46	M42-Y44 PolarHBondContact O-N 3.05Å; Y44-S46 PolarHBondContact O-N 2.88Å
45	W	82.5	Confident	85.3	Confident	21 Å²	21	64.1 Å²	64.1	8%	0.08	30%	0.304	C	S	.	.			trans	-68.1	130.3	176.3	-46.9	48.1	0	0	0	111.1	D55 S106 M107 F170 Y171	W45-D55 HydrophobicContact CB-CB 4.44Å; W45-D55 HydrophobicContact CD2-CB 4.27Å; W45-D55 HydrophobicContact CG-CB 4.03Å; W45-S106 WeakPolarHBondContact CH2-O 3.42Å; W45-M107 HydrophobicContact CB-CE 3.39Å; W45-M107 HydrophobicContact CB-SD 4.33Å; W45-M107 HydrophobicContact CD2-CE 3.42Å; W45-M107 VanDerWaalsContact CD2-CE 3.42Å; W45-M107 HydrophobicContact CD2-SD 3.24Å; W45-M107 VanDerWaalsContact CE2-SD 3.58Å; W45-M107 HydrophobicContact CE3-CE 3.29Å; W45-M107 HydrophobicContact CE3-CG 4.29Å; W45-M107 HydrophobicContact CE3-SD 3.21Å; W45-M107 HydrophobicContact CG-CE 3.59Å; W45-M107 HydrophobicContact CG-SD 3.85Å; W45-M107 HydrophobicContact CH2-SD 3.76Å; W45-M107 HydrophobicContact CZ2-SD 3.82Å; W45-M107 HydrophobicContact CZ3-CE 4.06Å; W45-M107 HydrophobicContact CZ3-CG 4.15Å; W45-M107 HydrophobicContact CZ3-SD 3.48Å; W45-M107 WeakPolarHBondContact CZ3-SD 3.48Å; W45-F170 HydrophobicContact CH2-CD2 4.15Å; W45-F170 HydrophobicContact CZ2-CB 4.28Å; W45-F170 HydrophobicContact CZ2-CD2 4.1Å; W45-Y171 WeakPolarHBondContact CA-OH 3.49Å; W45-Y171 HydrophobicContact CB-CE2 3.69Å; W45-Y171 WeakPolarHBondContact CB-OH 3.44Å; W45-Y171 AromaticContact CD1-CE1 3.3Å; W45-Y171 AromaticContact CD1-CE2 3.18Å; W45-Y171 AromaticContact CD1-CZ 2.8Å; W45-Y171 AromaticContact CD2-CE2 3.9Å; W45-Y171 HydrophobicContact CD2-CE2 3.9Å; W45-Y171 AromaticContact CE2-CE2 3.96Å; W45-Y171 HydrophobicContact CG-CD2 4.36Å; W45-Y171 HydrophobicContact CG-CE1 4.15Å; W45-Y171 AromaticContact CG-CE2 3.27Å; W45-Y171 HydrophobicContact CG-CE2 3.27Å; W45-Y171 AromaticContact CG-CZ 3.22Å; W45-Y171 PolarHBondContact N-OH 3.32Å; W45-Y171 AromaticContact NE1-CD2 3.95Å; W45-Y171 AromaticContact NE1-CE1 3.72Å; W45-Y171 AromaticContact NE1-CE2 3.49Å; W45-Y171 AromaticContact NE1-CZ 3.47Å
46	S	85.9	Confident	85.2	Confident	23 Å²	23	64.5 Å²	64.5	16%	0.161	31%	0.306	C	S	.	.	E	Extended strand (participates in β ladder)	trans	-109.6	171.3	178.9	67.9	0	0	0	0	110.1	N40 Y44 I48 C54	N40-S46 WeakPolarHBondContact CB-OG 3.27Å; Y44-S46 PolarHBondContact O-N 2.88Å; S46-I48 VanDerWaalsContact C-N 3.29Å; S46-I48 PolarHBondContact O-N 3.39Å; S46-C54 PolarHBondContact N-O 2.66Å; S46-C54 PolarHBondContact O-N 2.82Å; S46-C54 PolarHBondContact OG-O 3.29Å
47	E	82.7	Confident	85.3	Confident	69 Å²	69	62.5 Å²	62.5	32%	0.322	30%	0.296	S	S	.	.	E	Extended strand (participates in β ladder)	trans	51.8	40.9	176.4	-58.5	-169.5	-178.8	0	0	115.3	M1 N40 S49	M1-E47 PolarHBondContact N-OE2 3.49Å; N40-E47 PolarHBondContact ND2-OE1 3.19Å; E47-S49 PolarHBondContact O-N 3.37Å
48	I	85.5	Confident	85.5	Confident	107 Å²	107	55.9 Å²	55.9	55%	0.549	26%	0.261	S	S	.	.	E	Extended strand (participates in β ladder)	trans	-67.5	124.8	-176.6	-52.7	178.2	0	0	0	109.9	S46 L52 M107	S46-I48 VanDerWaalsContact C-N 3.29Å; S46-I48 PolarHBondContact O-N 3.39Å; I48-L52 WeakPolarHBondContact CA-O 3.48Å; I48-M107 HydrophobicContact CD1-CE 4.09Å; I48-M107 HydrophobicContact CG1-CE 3.78Å; I48-M107 HydrophobicContact CG2-CE 4.36Å
49	S	84.2	Confident	85.9	Confident	26 Å²	26	51.9 Å²	51.9	18%	0.182	24%	0.241	C	C	.	.	E	Extended strand (participates in β ladder)	trans	-146.6	125.8	170.3	61.8	0	0	0	0	109.8	L2 E47 F51 L52	L2-S49 WeakPolarHBondContact CG-OG 3.16Å; E47-S49 PolarHBondContact O-N 3.37Å; S49-F51 PolarHBondContact O-N 3.11Å; S49-F51 VanDerWaalsContact O-N 3.16Å; S49-L52 PolarHBondContact N-O 3.12Å; S49-L52 WeakPolarHBondContact O-CB 3.49Å; S49-L52 PolarHBondContact O-N 3.48Å
50	Y	87.3	Confident	86.5	Confident	209 Å²	209	48.3 Å²	48.3	82%	0.82	22%	0.222	S	C	*	.	T	Hydrogen-bonded Turn	trans	51.5	-114.3	-173	-57.5	-77.3	0	0	0	112.1	L2	L2-Y50 HydrophobicContact CD1-CD2 4.23Å; L2-Y50 HydrophobicContact CD1-CE2 4.1Å
51	F	90.7	Very high	87.5	Confident	69 Å²	69	47.2 Å²	47.2	30%	0.303	22%	0.217	S	C	.	.	T	Hydrogen-bonded Turn	trans	-98	3.1	178.1	61.5	-92.1	0	0	0	113.3	S49 L102 M107 M111 F115	S49-F51 PolarHBondContact O-N 3.11Å; S49-F51 VanDerWaalsContact O-N 3.16Å; F51-L102 HydrophobicContact CE2-CD2 4.35Å; F51-M107 VanDerWaalsContact O-CB 3.31Å; F51-M107 WeakPolarHBondContact O-CB 3.33Å; F51-M107 WeakPolarHBondContact O-CG 3.45Å; F51-M107 PolarHBondContact O-N 3.48Å; F51-M111 HydrophobicContact CE2-CE 4.3Å; F51-M111 HydrophobicContact CZ-CE 4.32Å; F51-F115 HydrophobicContact CD2-CE2 4.47Å; F51-F115 AromaticContact CE2-CE2 3.72Å; F51-F115 HydrophobicContact CE2-CE2 3.72Å; F51-F115 HydrophobicContact CE2-CZ 4.11Å; F51-F115 HydrophobicContact CZ-CE2 4.37Å; F51-F115 HydrophobicContact CZ-CZ 4.31Å
52	L	92.1	Very high	88.6	Confident	3 Å²	3	44.5 Å²	44.5	2%	0.016	21%	0.205	C	C	.	.	E	Extended strand (participates in β ladder)	trans	-102.4	143.1	-174.2	-56.9	165.6	0	0	0	110.5	M1 L2 I5 I48 S49 L102 S105	M1-L52 HydrophobicContact CB-CB 4.21Å; M1-L52 HydrophobicContact CB-CD1 4.46Å; L2-L52 HydrophobicContact CD2-CD1 4.13Å; I5-L52 HydrophobicContact CD1-CD1 3.33Å; I5-L52 HydrophobicContact CD1-CD2 4.32Å; I5-L52 HydrophobicContact CD1-CG 4.48Å; I48-L52 WeakPolarHBondContact CA-O 3.48Å; S49-L52 PolarHBondContact N-O 3.12Å; S49-L52 WeakPolarHBondContact O-CB 3.49Å; S49-L52 PolarHBondContact O-N 3.48Å; L52-L102 HydrophobicContact CD2-CD2 3.81Å; L52-S105 CarbonylContact C-O 3.59Å; L52-S105 VanDerWaalsContact CA-O 3.3Å; L52-S105 WeakPolarHBondContact CA-O 3.41Å; L52-S105 WeakPolarHBondContact CD2-OG 2.96Å
53	G	91.5	Very high	89.3	Confident	0 Å²	0	40 Å²	40	0%	0	18%	0.183	C	C	.	.	E	Extended strand (participates in β ladder)	trans	-163	177.2	159.8	0	0	0	0	0	111.7	S105	G53-S105 PolarHBondContact N-O 3.48Å; G53-S105 CarbonylContact O-C 3.59Å; G53-S105 VanDerWaalsContact O-CA 3.28Å; G53-S105 WeakPolarHBondContact O-CA 3.27Å; G53-S105 WeakPolarHBondContact O-CB 3.48Å; G53-S105 VanDerWaalsContact O-O 3.09Å
54	C	90.6	Very high	90	Very high	0 Å²	0	37.3 Å²	37.3	0%	0	17%	0.168	C	C	.	.	E	Extended strand (participates in β ladder)	trans	-137	118.8	179.4	-74.1	0	0	0	0	112.6	M1 S46 S58 I62	M1-C54 VanDerWaalsContact CE-SG 3.54Å; M1-C54 VanDerWaalsContact CG-SG 3.5Å; M1-C54 HydrophobicContact SD-CB 4.44Å; M1-C54 PolarHBondContact SD-SG 2.94Å; S46-C54 PolarHBondContact N-O 2.66Å; S46-C54 PolarHBondContact O-N 2.82Å; S46-C54 PolarHBondContact OG-O 3.29Å; C54-S58 VanDerWaalsContact CA-OG 3.28Å; C54-S58 WeakPolarHBondContact CA-OG 3.17Å; C54-I62 WeakPolarHBondContact SG-CD1 3.31Å
55	D	90.1	Very high	90.7	Very high	8 Å²	8	28.6 Å²	28.6	4%	0.043	13%	0.134	C	C	.	.			trans	-95.1	175.6	160.2	60.4	-6.3	0	0	0	111	W45 L57 S58 Y59 R233	W45-D55 HydrophobicContact CB-CB 4.44Å; W45-D55 HydrophobicContact CD2-CB 4.27Å; W45-D55 HydrophobicContact CG-CB 4.03Å; D55-L57 PolarHBondContact O-N 2.68Å; D55-L57 VanDerWaalsContact OD1-CB 3.31Å; D55-L57 WeakPolarHBondContact OD1-CB 3.42Å; D55-L57 WeakPolarHBondContact OD2-CB 3.23Å; D55-S58 PolarHBondContact N-OG 3.02Å; D55-S58 PolarHBondContact O-N 3.35Å; D55-S58 PolarHBondContact O-OG 2.79Å; D55-S58 VanDerWaalsContact OD1-CB 3.24Å; D55-S58 WeakPolarHBondContact OD1-CB 3.35Å; D55-S58 PolarHBondContact OD1-N 3.31Å; D55-S58 PolarHBondContact OD1-OG 3.46Å; D55-Y59 VanDerWaalsContact O-CB 3.29Å; D55-Y59 WeakPolarHBondContact O-CB 3.25Å; D55-Y59 PolarHBondContact O-N 3.17Å; D55-R233 IonicContact OD1-CZ 3.64Å; D55-R233 IonicContact OD1-NH2 3.88Å; D55-R233 PolarHBondContact OD1-NH2 3.46Å; D55-R233 IonicContact OD2-CZ 3.48Å; D55-R233 IonicContact OD2-NH1 3.06Å; D55-R233 PolarHBondContact OD2-NH1 3.35Å; D55-R233 IonicContact OD2-NH2 2.84Å; D55-R233 PolarHBondContact OD2-NH2 2.98Å
56	M	90.9	Very high	91.4	Very high	9 Å²	9	27.7 Å²	27.7	4%	0.044	13%	0.131	C	C	.	.	H	α-helix	trans	-52	-42.2	177.3	-178.6	-174.1	-100	0	0	112.4	F41 M42 Y59 G60 Y301 S441 W445	F41-M56 HydrophobicContact CB-CE 4.31Å; F41-M56 HydrophobicContact CD1-CE 4.27Å; M42-M56 PolarHBondContact O-N 2.99Å; M42-M56 VanDerWaalsContact O-N 3.14Å; M56-Y59 WeakPolarHBondContact O-CB 3.33Å; M56-Y59 PolarHBondContact O-N 2.95Å; M56-G60 PolarHBondContact O-N 3Å; M56-G60 VanDerWaalsContact O-N 3.11Å; M56-Y301 PolarHBondContact O-OH 3.46Å; M56-S441 VanDerWaalsContact CE-CA 3.44Å; M56-S441 VanDerWaalsContact CE-O 3.27Å; M56-S441 WeakPolarHBondContact CE-O 3.19Å; M56-S441 WeakPolarHBondContact CG-O 3.31Å; M56-W445 HydrophobicContact CB-CB 4.48Å; M56-W445 HydrophobicContact CG-CB 4.24Å; M56-W445 WeakPolarHBondContact SD-CA 3.5Å; M56-W445 HydrophobicContact SD-CB 3.51Å; M56-W445 VanDerWaalsContact SD-CB 3.51Å
57	L	92.5	Very high	91.9	Very high	15 Å²	15	27.8 Å²	27.8	8%	0.079	13%	0.128	C	C	.	.	H	α-helix	trans	-49.6	-62.4	176.1	-119	174.9	0	0	0	112.7	D55 Y229 L232 Y301 W445	D55-L57 PolarHBondContact O-N 2.68Å; D55-L57 VanDerWaalsContact OD1-CB 3.31Å; D55-L57 WeakPolarHBondContact OD1-CB 3.42Å; D55-L57 WeakPolarHBondContact OD2-CB 3.23Å; L57-Y229 HydrophobicContact CD2-CD2 4.18Å; L57-Y229 HydrophobicContact CD2-CE2 4.39Å; L57-L232 HydrophobicContact CD2-CD1 4.2Å; L57-Y301 HydrophobicContact CD2-CD2 4.17Å; L57-Y301 HydrophobicContact CD2-CE2 4.06Å; L57-Y301 WeakPolarHBondContact O-CE2 3.31Å; L57-Y301 PolarHBondContact O-OH 3.37Å; L57-W445 HydrophobicContact CB-CE3 4.3Å; L57-W445 HydrophobicContact CD1-CE3 4.03Å; L57-W445 HydrophobicContact CD1-CH2 4.49Å; L57-W445 HydrophobicContact CD1-CZ3 4Å; L57-W445 HydrophobicContact CD2-CE3 3.35Å; L57-W445 HydrophobicContact CD2-CH2 3.88Å; L57-W445 HydrophobicContact CD2-CZ3 2.94Å; L57-W445 HydrophobicContact CG-CD2 4.05Å; L57-W445 HydrophobicContact CG-CE3 3.2Å; L57-W445 HydrophobicContact CG-CH2 4.27Å; L57-W445 HydrophobicContact CG-CZ3 3.34Å
58	S	93.1	Very high	92.6	Very high	0 Å²	0	24.5 Å²	24.5	0%	0	11%	0.113	C	C	.	.	H	α-helix	trans	-68.5	-34.9	179.6	53.7	0	0	0	0	111.7	C54 D55 G60 L61 I62 F104	C54-S58 VanDerWaalsContact CA-OG 3.28Å; C54-S58 WeakPolarHBondContact CA-OG 3.17Å; D55-S58 PolarHBondContact N-OG 3.02Å; D55-S58 PolarHBondContact O-N 3.35Å; D55-S58 PolarHBondContact O-OG 2.79Å; D55-S58 VanDerWaalsContact OD1-CB 3.24Å; D55-S58 WeakPolarHBondContact OD1-CB 3.35Å; D55-S58 PolarHBondContact OD1-N 3.31Å; D55-S58 PolarHBondContact OD1-OG 3.46Å; S58-G60 PolarHBondContact O-N 3.26Å; S58-L61 PolarHBondContact O-N 3.03Å; S58-I62 WeakPolarHBondContact O-CB 3.44Å; S58-I62 WeakPolarHBondContact O-CD1 2.96Å; S58-I62 WeakPolarHBondContact O-CG1 3.43Å; S58-I62 PolarHBondContact O-N 3.36Å; S58-F104 WeakPolarHBondContact CB-O 3.37Å
59	Y	92.9	Very high	93.1	Very high	6 Å²	6	19.4 Å²	19.4	2%	0.024	9%	0.086	C	C	.	.	H	α-helix	trans	-55.1	-53.1	176.6	177	-96.1	0	0	0	111.6	F35 L36 N40 F41 D55 M56 L61 I62 L63	F35-Y59 HydrophobicContact CD1-CD2 4.26Å; F35-Y59 AromaticContact CD1-CE2 3.84Å; F35-Y59 HydrophobicContact CD1-CE2 3.84Å; F35-Y59 AromaticContact CE1-CD2 3.39Å; F35-Y59 HydrophobicContact CE1-CD2 3.39Å; F35-Y59 AromaticContact CE1-CE2 3.45Å; F35-Y59 HydrophobicContact CE1-CE2 3.45Å; F35-Y59 VanDerWaalsContact CE1-CE2 3.45Å; F35-Y59 HydrophobicContact CE1-CG 4.12Å; F35-Y59 WeakPolarHBondContact CE1-O 3.25Å; F35-Y59 HydrophobicContact CE2-CD2 4.09Å; F35-Y59 HydrophobicContact CE2-CE2 4.21Å; F35-Y59 HydrophobicContact CG-CE2 4.38Å; F35-Y59 AromaticContact CZ-CD2 3.31Å; F35-Y59 HydrophobicContact CZ-CD2 3.31Å; F35-Y59 AromaticContact CZ-CE2 3.68Å; F35-Y59 HydrophobicContact CZ-CE2 3.68Å; F35-Y59 HydrophobicContact CZ-CG 4.22Å; F35-Y59 WeakPolarHBondContact O-CE2 3.48Å; F35-Y59 PolarHBondContact O-OH 3.34Å; F35-Y59 VanDerWaalsContact O-OH 3.14Å; L36-Y59 WeakPolarHBondContact CA-OH 3.22Å; L36-Y59 PolarHBondContact O-OH 3.44Å; N40-Y59 HydrophobicContact CB-CD2 4.21Å; F41-Y59 HydrophobicContact CD1-CD1 4.43Å; F41-Y59 HydrophobicContact CD1-CE1 4.4Å; F41-Y59 AromaticContact CE1-CD1 3.97Å; F41-Y59 HydrophobicContact CE1-CD1 3.97Å; F41-Y59 AromaticContact CE1-CE1 3.62Å; F41-Y59 HydrophobicContact CE1-CE1 3.62Å; F41-Y59 AromaticContact CZ-CE1 3.86Å; F41-Y59 HydrophobicContact CZ-CE1 3.86Å; D55-Y59 VanDerWaalsContact O-CB 3.29Å; D55-Y59 WeakPolarHBondContact O-CB 3.25Å; D55-Y59 PolarHBondContact O-N 3.17Å; M56-Y59 WeakPolarHBondContact O-CB 3.33Å; M56-Y59 PolarHBondContact O-N 2.95Å; Y59-L61 VanDerWaalsContact C-N 3.32Å; Y59-L61 PolarHBondContact O-N 3.48Å; Y59-I62 PolarHBondContact O-N 3.48Å; Y59-L63 HydrophobicContact CE1-CD2 4.5Å; Y59-L63 WeakPolarHBondContact O-CB 3.33Å; Y59-L63 PolarHBondContact O-N 2.99Å
60	G	93.4	Very high	93.7	Very high	3 Å²	3	18.2 Å²	18.2	3%	0.031	8%	0.078	C	C	.	.	H	α-helix	trans	-63.2	-35.5	-179.2	0	0	0	0	0	113.7	M56 S58 L64 Y301	M56-G60 PolarHBondContact O-N 3Å; M56-G60 VanDerWaalsContact O-N 3.11Å; S58-G60 PolarHBondContact O-N 3.26Å; G60-L64 WeakPolarHBondContact O-CB 3.49Å; G60-L64 PolarHBondContact O-N 3.43Å; G60-Y301 VanDerWaalsContact CA-OH 3.25Å; G60-Y301 WeakPolarHBondContact CA-OH 3.48Å; G60-Y301 PolarHBondContact N-OH 2.77Å
61	L	95.2	Very high	94.1	Very high	2 Å²	2	8.2 Å²	8.2	1%	0.01	4%	0.039	C	C	.	.	H	α-helix	trans	-77.1	-35.5	178.6	-65.4	174.1	0	0	0	112.9	S58 Y59 L64 S65 F104 K225 Y229 Y301	S58-L61 PolarHBondContact O-N 3.03Å; Y59-L61 VanDerWaalsContact C-N 3.32Å; Y59-L61 PolarHBondContact O-N 3.48Å; L61-L64 PolarHBondContact O-N 3.18Å; L61-S65 WeakPolarHBondContact O-CB 3.32Å; L61-S65 PolarHBondContact O-N 2.84Å; L61-F104 HydrophobicContact CB-CD1 3.76Å; L61-F104 HydrophobicContact CB-CD2 4.1Å; L61-F104 HydrophobicContact CB-CE1 3.76Å; L61-F104 HydrophobicContact CB-CE2 4.1Å; L61-F104 HydrophobicContact CB-CG 3.94Å; L61-F104 HydrophobicContact CB-CZ 3.94Å; L61-F104 HydrophobicContact CD1-CD1 3.78Å; L61-F104 HydrophobicContact CD1-CE1 3.56Å; L61-F104 HydrophobicContact CD1-CZ 4.36Å; L61-F104 HydrophobicContact CG-CD1 4.42Å; L61-F104 HydrophobicContact CG-CE1 4.2Å; L61-K225 HydrophobicContact CD2-CB 4.17Å; L61-K225 HydrophobicContact CD2-CG 4.46Å; L61-Y229 HydrophobicContact CD1-CD2 3.58Å; L61-Y229 HydrophobicContact CD1-CG 3.93Å; L61-Y301 HydrophobicContact CG-CE2 4.23Å
62	I	95.8	Very high	94.4	Very high	0 Å²	0	5 Å²	5	0%	0	2%	0.024	C	C	.	.	H	α-helix	trans	-63.9	-45.4	172.2	-69.4	162.6	0	0	0	109.5	M1 F35 C54 S58 Y59 L64 S65 L66 I101 F104	M1-I62 HydrophobicContact CE-CD1 3.71Å; F35-I62 HydrophobicContact CD1-CG2 4.22Å; F35-I62 HydrophobicContact CE1-CB 3.88Å; F35-I62 HydrophobicContact CE1-CG2 3.61Å; F35-I62 HydrophobicContact CE2-CG2 4.08Å; F35-I62 HydrophobicContact CZ-CB 3.85Å; F35-I62 HydrophobicContact CZ-CD1 4.47Å; F35-I62 HydrophobicContact CZ-CG2 3.5Å; C54-I62 WeakPolarHBondContact SG-CD1 3.31Å; S58-I62 WeakPolarHBondContact O-CB 3.44Å; S58-I62 WeakPolarHBondContact O-CD1 2.96Å; S58-I62 WeakPolarHBondContact O-CG1 3.43Å; S58-I62 PolarHBondContact O-N 3.36Å; Y59-I62 PolarHBondContact O-N 3.48Å; I62-L64 PolarHBondContact O-N 3.24Å; I62-S65 WeakPolarHBondContact CA-OG 3.28Å; I62-S65 PolarHBondContact O-N 2.62Å; I62-S65 VanDerWaalsContact O-N 3.14Å; I62-S65 PolarHBondContact O-OG 2.97Å; I62-L66 HydrophobicContact CG2-CD1 4.12Å; I62-L66 PolarHBondContact O-N 3.39Å; I62-I101 HydrophobicContact CG2-CG1 4.29Å; I62-I101 HydrophobicContact CG2-CG2 4.45Å; I62-F104 HydrophobicContact CD1-CB 4.06Å; I62-F104 HydrophobicContact CG1-CB 3.56Å; I62-F104 HydrophobicContact CG1-CD2 4.35Å; I62-F104 HydrophobicContact CG1-CG 4.36Å
63	L	94.8	Very high	94.5	Very high	23 Å²	23	4.9 Å²	4.9	12%	0.12	2%	0.024	C	C	.	.	H	α-helix	trans	-58.1	-48.5	175.5	177.8	65.8	0	0	0	111.4	F35 L36 Y59 S65 L66 W67	F35-L63 HydrophobicContact CD1-CB 3.95Å; F35-L63 HydrophobicContact CD1-CD1 4.08Å; F35-L63 HydrophobicContact CE1-CB 3.95Å; L36-L63 HydrophobicContact CD1-CD1 4.25Å; L36-L63 HydrophobicContact CD2-CD1 3.51Å; L36-L63 HydrophobicContact CD2-CD2 3.49Å; L36-L63 VanDerWaalsContact CD2-CD2 3.49Å; L36-L63 HydrophobicContact CD2-CG 4.13Å; L36-L63 HydrophobicContact CG-CD1 3.49Å; L36-L63 VanDerWaalsContact CG-CD1 3.49Å; L36-L63 HydrophobicContact CG-CD2 4.43Å; Y59-L63 HydrophobicContact CE1-CD2 4.5Å; Y59-L63 WeakPolarHBondContact O-CB 3.33Å; Y59-L63 PolarHBondContact O-N 2.99Å; L63-S65 VanDerWaalsContact C-N 3.27Å; L63-S65 PolarHBondContact O-N 3.16Å; L63-L66 PolarHBondContact O-N 3.27Å; L63-W67 WeakPolarHBondContact O-CB 3.08Å; L63-W67 PolarHBondContact O-N 3.21Å
64	L	96	Very high	94.7	Very high	8 Å²	8	5.2 Å²	5.2	4%	0.042	3%	0.026	C	C	.	.	H	α-helix	trans	-57.7	-41.4	175.8	-172.5	77.2	0	0	0	111.2	G60 L61 I62 W67 I68 G221 I305 L309	G60-L64 WeakPolarHBondContact O-CB 3.49Å; G60-L64 PolarHBondContact O-N 3.43Å; L61-L64 PolarHBondContact O-N 3.18Å; I62-L64 PolarHBondContact O-N 3.24Å; L64-W67 PolarHBondContact O-N 2.97Å; L64-I68 HydrophobicContact CD1-CD1 3.9Å; L64-I68 HydrophobicContact CD1-CG1 4.38Å; L64-I68 HydrophobicContact CD2-CD1 4.28Å; L64-I68 HydrophobicContact CG-CD1 3.78Å; L64-I68 HydrophobicContact CG-CG1 4.37Å; L64-I68 WeakPolarHBondContact O-CG1 3.35Å; L64-I68 PolarHBondContact O-N 3.26Å; L64-G221 WeakPolarHBondContact CD2-O 3.33Å; L64-I305 HydrophobicContact CD1-CG2 4.5Å; L64-L309 HydrophobicContact CD1-CD2 3.77Å; L64-L309 HydrophobicContact CD1-CG 3.76Å
65	S	97.2	Very high	94.9	Very high	0 Å²	0	5.3 Å²	5.3	0%	0	3%	0.027	C	C	.	.	H	α-helix	trans	-65.9	-44.5	-179.8	72.7	0	0	0	0	113.5	L61 I62 L63 W67 C69 I222	L61-S65 WeakPolarHBondContact O-CB 3.32Å; L61-S65 PolarHBondContact O-N 2.84Å; I62-S65 WeakPolarHBondContact CA-OG 3.28Å; I62-S65 PolarHBondContact O-N 2.62Å; I62-S65 VanDerWaalsContact O-N 3.14Å; I62-S65 PolarHBondContact O-OG 2.97Å; L63-S65 VanDerWaalsContact C-N 3.27Å; L63-S65 PolarHBondContact O-N 3.16Å; S65-W67 VanDerWaalsContact C-N 3.28Å; S65-W67 PolarHBondContact O-N 3.15Å; S65-C69 VanDerWaalsContact O-CB 3.24Å; S65-C69 WeakPolarHBondContact O-CB 3.41Å; S65-C69 PolarHBondContact O-N 3.27Å; S65-C69 PolarHBondContact O-SG 3.25Å; S65-I222 VanDerWaalsContact CA-CD1 3.49Å
66	L	96.7	Very high	95	Very high	1 Å²	1	5.2 Å²	5.2	1%	0.005	3%	0.027	C	C	.	.	H	α-helix	trans	-59.5	-43	174.3	-74.5	167.8	0	0	0	110.7	I31 F35 I62 L63 S70 L97 I101	I31-L66 HydrophobicContact CB-CD2 4.32Å; I31-L66 HydrophobicContact CG2-CD1 4.11Å; I31-L66 HydrophobicContact CG2-CD2 3.73Å; F35-L66 HydrophobicContact CB-CD1 3.86Å; F35-L66 HydrophobicContact CD1-CD1 4.04Å; F35-L66 HydrophobicContact CG-CD1 3.95Å; I62-L66 HydrophobicContact CG2-CD1 4.12Å; I62-L66 PolarHBondContact O-N 3.39Å; L63-L66 PolarHBondContact O-N 3.27Å; L66-S70 PolarHBondContact O-N 3.37Å; L66-S70 PolarHBondContact O-OG 3.29Å; L66-L97 HydrophobicContact CD2-CD1 4.05Å; L66-L97 HydrophobicContact CD2-CD2 3.71Å; L66-L97 HydrophobicContact CD2-CG 4.36Å; L66-L97 HydrophobicContact CG-CD1 4.39Å; L66-I101 HydrophobicContact CD2-CD1 3.75Å; L66-I101 HydrophobicContact CG-CD1 4.12Å
67	W	97	Very high	95	Very high	26 Å²	26	6.1 Å²	6.1	10%	0.098	3%	0.031	C	C	.	.	H	α-helix	trans	-69.6	-46.2	-177.9	-166.3	-97	0	0	0	113.4	F33 L63 L64 S65 S70 L71 L427 P431	F33-W67 HydrophobicContact CE1-CZ3 4.28Å; F33-W67 HydrophobicContact CZ-CH2 4.4Å; F33-W67 HydrophobicContact CZ-CZ3 4.19Å; L63-W67 WeakPolarHBondContact O-CB 3.08Å; L63-W67 PolarHBondContact O-N 3.21Å; L64-W67 PolarHBondContact O-N 2.97Å; S65-W67 VanDerWaalsContact C-N 3.28Å; S65-W67 PolarHBondContact O-N 3.15Å; W67-S70 PolarHBondContact O-N 3.31Å; W67-S70 PolarHBondContact O-OG 2.98Å; W67-L71 HydrophobicContact CG-CD1 4.31Å; W67-L71 VanDerWaalsContact O-CG 3.3Å; W67-L71 WeakPolarHBondContact O-CG 3.27Å; W67-L71 PolarHBondContact O-N 3.35Å; W67-L71 VanDerWaalsContact O-N 3.11Å; W67-L427 HydrophobicContact CH2-CD2 4.02Å; W67-L427 HydrophobicContact CZ2-CB 4.16Å; W67-L427 HydrophobicContact CZ2-CD2 3.76Å; W67-L427 PolarHBondContact NE1-O 3.39Å; W67-P431 HydrophobicContact CZ2-CG 3.64Å
68	I	97.2	Very high	94.8	Very high	0 Å²	0	8.2 Å²	8.2	0%	0	4%	0.041	C	C	.	.	H	α-helix	trans	-70.7	-35	180	-65.5	179.9	0	0	0	110.8	L64 S70 L71 M72 M217 G221 I222	L64-I68 HydrophobicContact CD1-CD1 3.9Å; L64-I68 HydrophobicContact CD1-CG1 4.38Å; L64-I68 HydrophobicContact CD2-CD1 4.28Å; L64-I68 HydrophobicContact CG-CD1 3.78Å; L64-I68 HydrophobicContact CG-CG1 4.37Å; L64-I68 WeakPolarHBondContact O-CG1 3.35Å; L64-I68 PolarHBondContact O-N 3.26Å; I68-S70 VanDerWaalsContact C-N 3.3Å; I68-S70 PolarHBondContact O-N 2.96Å; I68-L71 PolarHBondContact O-N 2.79Å; I68-M72 PolarHBondContact O-N 2.82Å; I68-M217 HydrophobicContact CG2-CB 4.41Å; I68-G221 VanDerWaalsContact CD1-CA 3.46Å; I68-I222 HydrophobicContact CB-CD1 4.19Å; I68-I222 HydrophobicContact CD1-CG1 4.24Å; I68-I222 HydrophobicContact CG2-CD1 4.37Å
69	C	96.6	Very high	94.7	Very high	0 Å²	0	9 Å²	9	0%	0	5%	0.045	C	C	.	.	H	α-helix	trans	-69.4	-23.3	176.4	-72.4	0	0	0	0	113.8	M28 S65 M72 L97	M28-C69 HydrophobicContact CE-CB 3.92Å; S65-C69 VanDerWaalsContact O-CB 3.24Å; S65-C69 WeakPolarHBondContact O-CB 3.41Å; S65-C69 PolarHBondContact O-N 3.27Å; S65-C69 PolarHBondContact O-SG 3.25Å; C69-M72 HydrophobicContact CB-SD 4.11Å; C69-M72 WeakPolarHBondContact O-CG 3.44Å; C69-L97 HydrophobicContact CB-CB 4.34Å; C69-L97 HydrophobicContact CB-CD1 4.07Å
70	S	96.1	Very high	94.5	Very high	0 Å²	0	10.1 Å²	10.1	0%	0	5%	0.051	C	C	.	.	H	α-helix	trans	-80.2	-37.6	169.1	64.2	0	0	0	0	111.6	F29 L66 W67 I68 L73 L74	F29-S70 WeakPolarHBondContact CD1-OG 3.06Å; F29-S70 WeakPolarHBondContact CE1-OG 3.22Å; F29-S70 WeakPolarHBondContact CZ-OG 3.4Å; L66-S70 PolarHBondContact O-N 3.37Å; L66-S70 PolarHBondContact O-OG 3.29Å; W67-S70 PolarHBondContact O-N 3.31Å; W67-S70 PolarHBondContact O-OG 2.98Å; I68-S70 VanDerWaalsContact C-N 3.3Å; I68-S70 PolarHBondContact O-N 2.96Å; S70-L73 PolarHBondContact O-N 3.3Å; S70-L74 PolarHBondContact O-N 3.42Å
71	L	96.6	Very high	94.2	Very high	0 Å²	0	14.9 Å²	14.9	0%	0	7%	0.071	C	C	.	.	H	α-helix	trans	-67.1	-34.1	177	-70.9	167.7	0	0	0	113.6	F29 W67 I68 L73 L74 A75 M217 L424 L427	F29-L71 HydrophobicContact CZ-CD2 4.26Å; W67-L71 HydrophobicContact CG-CD1 4.31Å; W67-L71 VanDerWaalsContact O-CG 3.3Å; W67-L71 WeakPolarHBondContact O-CG 3.27Å; W67-L71 PolarHBondContact O-N 3.35Å; W67-L71 VanDerWaalsContact O-N 3.11Å; I68-L71 PolarHBondContact O-N 2.79Å; L71-L73 VanDerWaalsContact C-N 3.26Å; L71-L73 PolarHBondContact O-N 2.84Å; L71-L74 HydrophobicContact CD2-CD1 4.13Å; L71-L74 WeakPolarHBondContact O-CB 3.42Å; L71-L74 PolarHBondContact O-N 3.26Å; L71-A75 PolarHBondContact O-N 3.29Å; L71-M217 HydrophobicContact CB-CE 3.81Å; L71-L424 HydrophobicContact CD2-CG 4.48Å; L71-L427 HydrophobicContact CD2-CB 3.54Å; L71-L427 HydrophobicContact CD2-CD1 3.79Å; L71-L427 HydrophobicContact CD2-CG 4.33Å
72	M	96	Very high	93.9	Very high	0 Å²	0	20.2 Å²	20.2	0%	0	10%	0.096	C	C	.	.	H	α-helix	trans	-62.1	-36	176.5	65.3	-179.6	-53.2	0	0	112.2	I68 C69 A75 S76 I93 L126 S214 I218	I68-M72 PolarHBondContact O-N 2.82Å; C69-M72 HydrophobicContact CB-SD 4.11Å; C69-M72 WeakPolarHBondContact O-CG 3.44Å; M72-A75 WeakPolarHBondContact O-CB 3.28Å; M72-A75 PolarHBondContact O-N 3Å; M72-S76 PolarHBondContact O-N 3.5Å; M72-S76 PolarHBondContact O-OG 3.07Å; M72-I93 HydrophobicContact CE-CB 4.39Å; M72-I93 HydrophobicContact CE-CD1 3.38Å; M72-I93 HydrophobicContact CE-CG1 3.4Å; M72-I93 HydrophobicContact CE-CG2 4.23Å; M72-I93 HydrophobicContact CG-CD1 4.23Å; M72-I93 HydrophobicContact CG-CG2 4.34Å; M72-I93 HydrophobicContact SD-CB 4.24Å; M72-I93 HydrophobicContact SD-CD1 3.9Å; M72-I93 HydrophobicContact SD-CG1 3.85Å; M72-I93 HydrophobicContact SD-CG2 3.46Å; M72-I93 WeakPolarHBondContact SD-CG2 3.12Å; M72-L126 HydrophobicContact CE-CD1 4.39Å; M72-S214 VanDerWaalsContact CE-CB 3.46Å; M72-I218 HydrophobicContact CE-CD1 3.09Å; M72-I218 HydrophobicContact CE-CG1 3.88Å; M72-I218 HydrophobicContact SD-CD1 3.53Å; M72-I218 VanDerWaalsContact SD-CD1 3.53Å; M72-I218 HydrophobicContact SD-CG1 3.85Å
73	L	95.1	Very high	93.5	Very high	1 Å²	1	25 Å²	25	1%	0.005	12%	0.121	C	C	.	.	H	α-helix	trans	-68.1	-37.5	177.4	-71.2	175.3	0	0	0	111.1	Y21 V24 Q25 S70 L71 A75 S76 F89 L90 I93	Y21-L73 WeakPolarHBondContact CE1-O 2.92Å; Y21-L73 HydrophobicContact CE2-CD2 4.25Å; Y21-L73 PolarHBondContact OH-O 3.21Å; V24-L73 HydrophobicContact CG1-CD1 4.32Å; Q25-L73 HydrophobicContact CB-CB 4.14Å; Q25-L73 HydrophobicContact CB-CD1 3.99Å; Q25-L73 HydrophobicContact CG-CB 3.89Å; Q25-L73 HydrophobicContact CG-CD1 4.34Å; S70-L73 PolarHBondContact O-N 3.3Å; L71-L73 VanDerWaalsContact C-N 3.26Å; L71-L73 PolarHBondContact O-N 2.84Å; L73-A75 VanDerWaalsContact C-N 3.34Å; L73-S76 PolarHBondContact O-OG 3.49Å; L73-F89 HydrophobicContact CD2-CE1 4.11Å; L73-L90 HydrophobicContact CD1-CD2 4.47Å; L73-L90 HydrophobicContact CD2-CD2 3.43Å; L73-L90 VanDerWaalsContact CD2-CD2 3.43Å; L73-I93 HydrophobicContact CD2-CD1 3.35Å; L73-I93 HydrophobicContact CD2-CG2 4.48Å; L73-I93 HydrophobicContact CG-CD1 4.12Å; L73-I93 HydrophobicContact CG-CG2 4.44Å
74	L	95	Very high	93.1	Very high	8 Å²	8	28 Å²	28	4%	0.042	14%	0.138	C	C	.	.	H	α-helix	trans	-62.2	-42.6	170.8	-79.7	169	0	0	0	111.7	W22 Q25 F29 S70 L71 R420 L423 L424 L427	W22-L74 HydrophobicContact CZ3-CD2 4.25Å; Q25-L74 VanDerWaalsContact CD-CG 3.44Å; Q25-L74 HydrophobicContact CG-CG 4.41Å; F29-L74 HydrophobicContact CE2-CD1 3.71Å; F29-L74 HydrophobicContact CE2-CG 4.28Å; F29-L74 HydrophobicContact CZ-CD1 3.64Å; S70-L74 PolarHBondContact O-N 3.42Å; L71-L74 HydrophobicContact CD2-CD1 4.13Å; L71-L74 WeakPolarHBondContact O-CB 3.42Å; L71-L74 PolarHBondContact O-N 3.26Å; L74-R420 HydrophobicContact CD2-CG 4.39Å; L74-R420 WeakPolarHBondContact O-CD 3.3Å; L74-R420 PolarHBondContact O-NH1 3.13Å; L74-L423 HydrophobicContact CD1-CD2 3.65Å; L74-L423 HydrophobicContact CD2-CD2 4.06Å; L74-L424 HydrophobicContact CB-CD1 4.1Å; L74-L427 HydrophobicContact CD1-CD1 3.94Å
75	A	94.6	Very high	92.9	Very high	2 Å²	2	36.1 Å²	36.1	2%	0.017	17%	0.169	C	C	.	.	H	α-helix	trans	-63.9	-42.8	-178.7	0	0	0	0	0	111.6	L71 M72 L73 E77 V213 M217 R420 L424	L71-A75 PolarHBondContact O-N 3.29Å; M72-A75 WeakPolarHBondContact O-CB 3.28Å; M72-A75 PolarHBondContact O-N 3Å; L73-A75 VanDerWaalsContact C-N 3.34Å; A75-E77 VanDerWaalsContact C-N 3.29Å; A75-E77 PolarHBondContact O-N 3.28Å; A75-E77 VanDerWaalsContact O-N 3.09Å; A75-V213 HydrophobicContact CB-CG1 3.99Å; A75-M217 HydrophobicContact CB-SD 3.65Å; A75-R420 PolarHBondContact O-NH1 3.23Å; A75-L424 HydrophobicContact CB-CD1 3.62Å
76	S	93	Very high	92.7	Very high	6 Å²	6	37.6 Å²	37.6	4%	0.042	18%	0.175	C	C	.	.	T	Hydrogen-bonded Turn	trans	-85.9	38.4	-171.1	58.5	0	0	0	0	115.5	Y21 M72 L73 M78 I79 F89	Y21-S76 PolarHBondContact OH-O 3.42Å; Y21-S76 PolarHBondContact OH-OG 2.92Å; M72-S76 PolarHBondContact O-N 3.5Å; M72-S76 PolarHBondContact O-OG 3.07Å; L73-S76 PolarHBondContact O-OG 3.49Å; S76-M78 PolarHBondContact O-N 3.4Å; S76-I79 PolarHBondContact O-N 3.35Å; S76-F89 WeakPolarHBondContact OG-CE1 3.47Å; S76-F89 WeakPolarHBondContact OG-CZ 3.47Å
77	E	90	Very high	92.5	Very high	28 Å²	28	39.5 Å²	39.5	13%	0.131	19%	0.186	C	C	.	.	H	α-helix	trans	-60.7	-32.5	176.3	-173.9	-167.9	-162.8	0	0	112.3	W22 A75 I79 N80 K81 R420	W22-E77 HydrophobicContact CH2-CB 4.33Å; W22-E77 HydrophobicContact CH2-CG 4.05Å; W22-E77 HydrophobicContact CZ2-CG 4.05Å; A75-E77 VanDerWaalsContact C-N 3.29Å; A75-E77 PolarHBondContact O-N 3.28Å; A75-E77 VanDerWaalsContact O-N 3.09Å; E77-I79 PolarHBondContact O-N 3.27Å; E77-N80 CarbonylContact O-C 3.46Å; E77-N80 WeakPolarHBondContact O-CA 3.4Å; E77-N80 WeakPolarHBondContact O-CB 3.43Å; E77-N80 PolarHBondContact O-N 3.49Å; E77-K81 HydrophobicContact CG-CD 3.99Å; E77-K81 HydrophobicContact CG-CG 4.15Å; E77-K81 PolarHBondContact O-N 2.93Å; E77-K81 WeakPolarHBondContact OE1-CE 3.34Å; E77-K81 IonicContact OE1-NZ 2.96Å; E77-K81 PolarHBondContact OE1-NZ 3.24Å; E77-K81 IonicContact OE2-NZ 3.26Å; E77-K81 PolarHBondContact OE2-NZ 3.13Å; E77-R420 VanDerWaalsContact CB-CZ 3.44Å; E77-R420 IonicContact OE2-CZ 3.52Å; E77-R420 IonicContact OE2-NE 3.03Å; E77-R420 PolarHBondContact OE2-NE 3.36Å; E77-R420 IonicContact OE2-NH1 2.83Å; E77-R420 IonicContact OE2-NH2 3.59Å; E77-R420 PolarHBondContact OE2-NH2 3.24Å
78	M	88.9	Confident	92.4	Very high	58 Å²	58	42.6 Å²	42.6	29%	0.286	20%	0.203	S	C	.	.	H	α-helix	trans	-57.4	-33.8	179.2	-68.4	-63	-79.5	0	0	112.2	S76 K81 H82 E323	S76-M78 PolarHBondContact O-N 3.4Å; M78-K81 PolarHBondContact O-N 2.94Å; M78-K81 HydrophobicContact SD-CD 4.41Å; M78-H82 WeakPolarHBondContact CE-NE2 3.37Å; M78-H82 WeakPolarHBondContact O-CB 3.44Å; M78-H82 PolarHBondContact O-CD2 3.48Å; M78-H82 PolarHBondContact O-N 3.43Å; M78-E323 HydrophobicContact CG-CG 4.25Å; M78-E323 WeakPolarHBondContact CG-OE1 3.16Å
79	I	90.5	Very high	92.3	Very high	17 Å²	17	42.6 Å²	42.6	9%	0.087	20%	0.203	C	C	.	.	H	α-helix	trans	-66.6	-41.2	176.4	-57	179.9	0	0	0	110.6	S76 E77 N83 N84 F89 W130	S76-I79 PolarHBondContact O-N 3.35Å; E77-I79 PolarHBondContact O-N 3.27Å; I79-N83 PolarHBondContact O-N 3.31Å; I79-N83 VanDerWaalsContact O-N 3.12Å; I79-N84 HydrophobicContact CG2-CB 4.42Å; I79-N84 WeakPolarHBondContact CG2-O 3.15Å; I79-N84 PolarHBondContact O-N 2.7Å; I79-N84 VanDerWaalsContact O-N 3.16Å; I79-F89 HydrophobicContact CD1-CD1 4.21Å; I79-F89 HydrophobicContact CD1-CD2 3.7Å; I79-F89 HydrophobicContact CD1-CE1 3.95Å; I79-F89 HydrophobicContact CD1-CE2 3.4Å; I79-F89 VanDerWaalsContact CD1-CE2 3.4Å; I79-F89 HydrophobicContact CD1-CG 4.07Å; I79-F89 HydrophobicContact CD1-CZ 3.52Å; I79-F89 HydrophobicContact CG2-CB 4.34Å; I79-F89 HydrophobicContact CG2-CD1 4.41Å; I79-F89 HydrophobicContact CG2-CG 4.25Å; I79-W130 HydrophobicContact CD1-CB 4.33Å; I79-W130 HydrophobicContact CD1-CG 4.05Å
80	N	88.2	Confident	92.2	Very high	29 Å²	29	42.7 Å²	42.7	16%	0.155	20%	0.204	C	C	.	.	H	α-helix	trans	-68.9	-41.6	176.4	-167.3	24.8	0	0	0	111.4	Y21 E77 N83	Y21-N80 HydrophobicContact CD1-CB 4.28Å; Y21-N80 HydrophobicContact CD2-CB 4.16Å; Y21-N80 HydrophobicContact CE1-CB 4.39Å; Y21-N80 HydrophobicContact CE2-CB 4.26Å; Y21-N80 HydrophobicContact CG-CB 4.19Å; E77-N80 CarbonylContact O-C 3.46Å; E77-N80 WeakPolarHBondContact O-CA 3.4Å; E77-N80 WeakPolarHBondContact O-CB 3.43Å; E77-N80 PolarHBondContact O-N 3.49Å; N80-N83 PolarHBondContact O-N 3.2Å; N80-N83 PolarHBondContact O-OD1 3Å
81	K	88	Confident	92.2	Very high	103 Å²	103	44.2 Å²	44.2	45%	0.448	21%	0.212	S	C	.	.	H	α-helix	trans	-62.7	-43.5	178	-79.5	176.4	168.9	163	0	113.1	E77 M78 N83	E77-K81 HydrophobicContact CG-CD 3.99Å; E77-K81 HydrophobicContact CG-CG 4.15Å; E77-K81 PolarHBondContact O-N 2.93Å; E77-K81 WeakPolarHBondContact OE1-CE 3.34Å; E77-K81 IonicContact OE1-NZ 2.96Å; E77-K81 PolarHBondContact OE1-NZ 3.24Å; E77-K81 IonicContact OE2-NZ 3.26Å; E77-K81 PolarHBondContact OE2-NZ 3.13Å; M78-K81 PolarHBondContact O-N 2.94Å; M78-K81 HydrophobicContact SD-CD 4.41Å; K81-N83 VanDerWaalsContact C-N 3.31Å
82	H	89.1	Confident	92.1	Very high	114 Å²	114	45.1 Å²	45.1	53%	0.528	22%	0.217	S	C	.	.	T	Hydrogen-bonded Turn	trans	-84	-3.2	178.4	-65.2	-59.4	0	0	0	113.7	M78 N84	M78-H82 WeakPolarHBondContact CE-NE2 3.37Å; M78-H82 WeakPolarHBondContact O-CB 3.44Å; M78-H82 PolarHBondContact O-CD2 3.48Å; M78-H82 PolarHBondContact O-N 3.43Å; H82-N84 PolarHBondContact O-N 3.32Å; H82-N84 PolarHBondContact O-OD1 3.22Å
83	N	86.8	Confident	92.2	Very high	100 Å²	100	45.2 Å²	45.2	54%	0.535	22%	0.217	S	C	.	.	T	Hydrogen-bonded Turn	trans	52.5	31.2	-172.9	-72.8	-51.9	0	0	0	113.9	I79 N80 K81 Y85 K86	I79-N83 PolarHBondContact O-N 3.31Å; I79-N83 VanDerWaalsContact O-N 3.12Å; N80-N83 PolarHBondContact O-N 3.2Å; N80-N83 PolarHBondContact O-OD1 3Å; K81-N83 VanDerWaalsContact C-N 3.31Å; N83-Y85 PolarHBondContact O-N 3.26Å; N83-K86 PolarHBondContact OD1-NZ 3.45Å; N83-K86 VanDerWaalsContact OD1-NZ 3.09Å
84	N	87.7	Confident	92.2	Very high	88 Å²	88	45.2 Å²	45.2	47%	0.471	22%	0.217	S	C	.	.	S	Bend	trans	-74.7	87.1	-178.9	-74.3	-3.5	0	0	0	111.1	I79 H82 K86 W130	I79-N84 HydrophobicContact CG2-CB 4.42Å; I79-N84 WeakPolarHBondContact CG2-O 3.15Å; I79-N84 PolarHBondContact O-N 2.7Å; I79-N84 VanDerWaalsContact O-N 3.16Å; H82-N84 PolarHBondContact O-N 3.32Å; H82-N84 PolarHBondContact O-OD1 3.22Å; N84-K86 PolarHBondContact O-N 3.4Å; N84-K86 VanDerWaalsContact O-N 3.17Å; N84-W130 PolarHBondContact O-NE1 3.36Å; N84-W130 VanDerWaalsContact O-NE1 3.07Å
85	Y	91.1	Very high	92.3	Very high	178 Å²	178	47.8 Å²	47.8	70%	0.698	23%	0.23	S	C	*	.	S	Bend	trans	46.1	46.5	179.3	-65.8	-74.2	0	0	0	113.6	N83 N87 L88 F89	N83-Y85 PolarHBondContact O-N 3.26Å; Y85-N87 VanDerWaalsContact C-N 3.28Å; Y85-N87 PolarHBondContact O-N 3.09Å; Y85-L88 HydrophobicContact CD1-CD1 3.95Å; Y85-L88 HydrophobicContact CG-CD1 4.34Å; Y85-L88 PolarHBondContact O-N 2.88Å; Y85-F89 PolarHBondContact O-N 3.14Å
86	K	92.4	Very high	92.4	Very high	31 Å²	31	47.7 Å²	47.7	14%	0.135	23%	0.229	C	C	.	.	H	α-helix	trans	-55.9	-38.2	-173.4	70.2	-174.3	177.6	-168.9	0	113.7	N83 N84 F89 L90	N83-K86 PolarHBondContact OD1-NZ 3.45Å; N83-K86 VanDerWaalsContact OD1-NZ 3.09Å; N84-K86 PolarHBondContact O-N 3.4Å; N84-K86 VanDerWaalsContact O-N 3.17Å; K86-F89 WeakPolarHBondContact O-CB 3.48Å; K86-F89 PolarHBondContact O-N 3.45Å; K86-L90 WeakPolarHBondContact O-CG 3.16Å; K86-L90 PolarHBondContact O-N 3.3Å
87	N	93	Very high	92.6	Very high	41 Å²	41	47.4 Å²	47.4	22%	0.219	23%	0.227	C	C	.	.	H	α-helix	trans	-68.6	-40.9	-178.1	-63.4	2.2	0	0	0	111.4	C15 Y85 F89 L90 L91	C15-N87 PolarHBondContact O-OD1 2.93Å; Y85-N87 VanDerWaalsContact C-N 3.28Å; Y85-N87 PolarHBondContact O-N 3.09Å; N87-F89 VanDerWaalsContact C-N 3.32Å; N87-L90 PolarHBondContact O-N 3.22Å; N87-L91 WeakPolarHBondContact O-CB 3.27Å; N87-L91 PolarHBondContact O-N 2.86Å
88	L	93.8	Very high	92.9	Very high	90 Å²	90	47.4 Å²	47.4	47%	0.471	23%	0.228	S	C	.	.	H	α-helix	trans	-67	-36.2	175.4	-67.2	174.9	0	0	0	111.4	Y85 L91 N92 W130	Y85-L88 HydrophobicContact CD1-CD1 3.95Å; Y85-L88 HydrophobicContact CG-CD1 4.34Å; Y85-L88 PolarHBondContact O-N 2.88Å; L88-L91 PolarHBondContact O-N 3.46Å; L88-N92 WeakPolarHBondContact O-CB 2.99Å; L88-N92 PolarHBondContact O-N 3.42Å; L88-W130 HydrophobicContact CB-CH2 4.46Å; L88-W130 HydrophobicContact CB-CZ2 4.38Å
89	F	95.1	Very high	93.3	Very high	0 Å²	0	45.7 Å²	45.7	0%	0	22%	0.22	C	C	.	.	H	α-helix	trans	-61.7	-50.2	174.8	-178.4	-105.1	0	0	0	111.6	Y21 L73 S76 I79 Y85 K86 N87 L91 N92 I93 L126 W130 S214	Y21-F89 HydrophobicContact CE2-CD1 4.37Å; L73-F89 HydrophobicContact CD2-CE1 4.11Å; S76-F89 WeakPolarHBondContact OG-CE1 3.47Å; S76-F89 WeakPolarHBondContact OG-CZ 3.47Å; I79-F89 HydrophobicContact CD1-CD1 4.21Å; I79-F89 HydrophobicContact CD1-CD2 3.7Å; I79-F89 HydrophobicContact CD1-CE1 3.95Å; I79-F89 HydrophobicContact CD1-CE2 3.4Å; I79-F89 VanDerWaalsContact CD1-CE2 3.4Å; I79-F89 HydrophobicContact CD1-CG 4.07Å; I79-F89 HydrophobicContact CD1-CZ 3.52Å; I79-F89 HydrophobicContact CG2-CB 4.34Å; I79-F89 HydrophobicContact CG2-CD1 4.41Å; I79-F89 HydrophobicContact CG2-CG 4.25Å; Y85-F89 PolarHBondContact O-N 3.14Å; K86-F89 WeakPolarHBondContact O-CB 3.48Å; K86-F89 PolarHBondContact O-N 3.45Å; N87-F89 VanDerWaalsContact C-N 3.32Å; F89-L91 VanDerWaalsContact C-N 3.35Å; F89-L91 PolarHBondContact O-N 2.94Å; F89-N92 PolarHBondContact O-N 3.44Å; F89-I93 HydrophobicContact CD1-CD1 3.72Å; F89-I93 HydrophobicContact CD2-CD1 4.46Å; F89-I93 HydrophobicContact CE1-CD1 3.2Å; F89-I93 HydrophobicContact CE1-CG1 4.42Å; F89-I93 HydrophobicContact CE2-CD1 4.03Å; F89-I93 HydrophobicContact CG-CD1 4.33Å; F89-I93 HydrophobicContact CZ-CD1 3.4Å; F89-I93 HydrophobicContact CZ-CG1 4.41Å; F89-I93 WeakPolarHBondContact O-CG1 3.34Å; F89-I93 PolarHBondContact O-N 2.96Å; F89-I93 VanDerWaalsContact O-N 3.11Å; F89-L126 HydrophobicContact CD2-CD2 3.87Å; F89-L126 HydrophobicContact CE2-CD2 3.63Å; F89-W130 VanDerWaalsContact CA-CH2 3.49Å; F89-W130 HydrophobicContact CB-CH2 3.95Å; F89-W130 HydrophobicContact CB-CZ2 3.37Å; F89-W130 AromaticContact CD2-CD2 3.66Å; F89-W130 HydrophobicContact CD2-CD2 3.66Å; F89-W130 AromaticContact CD2-CE2 3.67Å; F89-W130 AromaticContact CD2-CE3 3.89Å; F89-W130 HydrophobicContact CD2-CE3 3.89Å; F89-W130 HydrophobicContact CD2-CG 4.21Å; F89-W130 HydrophobicContact CD2-CH2 4.13Å; F89-W130 AromaticContact CD2-CZ2 3.93Å; F89-W130 HydrophobicContact CD2-CZ2 3.93Å; F89-W130 HydrophobicContact CD2-CZ3 4.11Å; F89-W130 HydrophobicContact CE2-CD2 4.4Å; F89-W130 HydrophobicContact CG-CZ2 4.14Å; F89-S214 WeakPolarHBondContact CE2-OG 3.45Å
90	L	94.9	Very high	93.7	Very high	2 Å²	2	44.9 Å²	44.9	1%	0.01	22%	0.216	C	C	.	.	H	α-helix	trans	-58.5	-46.7	176.8	-70.5	175.9	0	0	0	111.6	C15 Y21 V24 L73 K86 N87 N92 I93 I94	C15-L90 HydrophobicContact CB-CB 4.04Å; Y21-L90 HydrophobicContact CD2-CD1 3.92Å; Y21-L90 HydrophobicContact CD2-CD2 3.58Å; Y21-L90 HydrophobicContact CD2-CG 3.9Å; Y21-L90 HydrophobicContact CE2-CD2 3.66Å; Y21-L90 HydrophobicContact CE2-CG 4.23Å; Y21-L90 HydrophobicContact CG-CD2 4.37Å; V24-L90 HydrophobicContact CG1-CD2 4.4Å; L73-L90 HydrophobicContact CD1-CD2 4.47Å; L73-L90 HydrophobicContact CD2-CD2 3.43Å; L73-L90 VanDerWaalsContact CD2-CD2 3.43Å; K86-L90 WeakPolarHBondContact O-CG 3.16Å; K86-L90 PolarHBondContact O-N 3.3Å; N87-L90 PolarHBondContact O-N 3.22Å; L90-N92 PolarHBondContact O-N 3.01Å; L90-I93 PolarHBondContact O-N 3Å; L90-I94 WeakPolarHBondContact O-CG1 3.44Å; L90-I94 PolarHBondContact O-N 3.48Å
91	L	95.7	Very high	94	Very high	32 Å²	32	43.5 Å²	43.5	17%	0.168	21%	0.209	C	C	.	.	H	α-helix	trans	-59.4	-45.2	178.1	177.2	138.1	0	0	0	111.9	I12 F16 N87 L88 F89 I93 I94 I95	I12-L91 HydrophobicContact CG2-CD1 4.42Å; F16-L91 HydrophobicContact CE1-CD1 4.21Å; F16-L91 HydrophobicContact CE2-CD1 3.76Å; F16-L91 HydrophobicContact CZ-CD1 3.3Å; N87-L91 WeakPolarHBondContact O-CB 3.27Å; N87-L91 PolarHBondContact O-N 2.86Å; L88-L91 PolarHBondContact O-N 3.46Å; F89-L91 VanDerWaalsContact C-N 3.35Å; F89-L91 PolarHBondContact O-N 2.94Å; L91-I93 VanDerWaalsContact C-N 3.27Å; L91-I93 PolarHBondContact O-N 3.16Å; L91-I94 PolarHBondContact O-N 3.31Å; L91-I95 HydrophobicContact CD2-CD1 3.39Å; L91-I95 HydrophobicContact CD2-CG1 4.44Å; L91-I95 HydrophobicContact CG-CD1 3.83Å; L91-I95 HydrophobicContact CG-CG1 4.46Å; L91-I95 VanDerWaalsContact O-CG1 3.31Å; L91-I95 WeakPolarHBondContact O-CG1 3.31Å; L91-I95 PolarHBondContact O-N 2.98Å
92	N	96.3	Very high	94.4	Very high	20 Å²	20	39.4 Å²	39.4	11%	0.107	19%	0.192	C	C	.	.	H	α-helix	trans	-61	-36.8	177.6	-79.1	-13	0	0	0	112.4	L88 F89 L90 L96 W130	L88-N92 WeakPolarHBondContact O-CB 2.99Å; L88-N92 PolarHBondContact O-N 3.42Å; F89-N92 PolarHBondContact O-N 3.44Å; L90-N92 PolarHBondContact O-N 3.01Å; N92-L96 VanDerWaalsContact O-CB 3.27Å; N92-L96 WeakPolarHBondContact O-CB 3.49Å; N92-L96 PolarHBondContact O-N 3.23Å; N92-W130 WeakPolarHBondContact ND2-CH2 2.83Å; N92-W130 WeakPolarHBondContact ND2-CZ3 3.42Å
93	I	96.2	Very high	94.8	Very high	1 Å²	1	34 Å²	34	1%	0.005	17%	0.167	C	C	.	.	H	α-helix	trans	-67.4	-44.7	177.4	-68.5	174.8	0	0	0	111.6	M72 L73 F89 L90 L91 L96 L97	M72-I93 HydrophobicContact CE-CB 4.39Å; M72-I93 HydrophobicContact CE-CD1 3.38Å; M72-I93 HydrophobicContact CE-CG1 3.4Å; M72-I93 HydrophobicContact CE-CG2 4.23Å; M72-I93 HydrophobicContact CG-CD1 4.23Å; M72-I93 HydrophobicContact CG-CG2 4.34Å; M72-I93 HydrophobicContact SD-CB 4.24Å; M72-I93 HydrophobicContact SD-CD1 3.9Å; M72-I93 HydrophobicContact SD-CG1 3.85Å; M72-I93 HydrophobicContact SD-CG2 3.46Å; M72-I93 WeakPolarHBondContact SD-CG2 3.12Å; L73-I93 HydrophobicContact CD2-CD1 3.35Å; L73-I93 HydrophobicContact CD2-CG2 4.48Å; L73-I93 HydrophobicContact CG-CD1 4.12Å; L73-I93 HydrophobicContact CG-CG2 4.44Å; F89-I93 HydrophobicContact CD1-CD1 3.72Å; F89-I93 HydrophobicContact CD2-CD1 4.46Å; F89-I93 HydrophobicContact CE1-CD1 3.2Å; F89-I93 HydrophobicContact CE1-CG1 4.42Å; F89-I93 HydrophobicContact CE2-CD1 4.03Å; F89-I93 HydrophobicContact CG-CD1 4.33Å; F89-I93 HydrophobicContact CZ-CD1 3.4Å; F89-I93 HydrophobicContact CZ-CG1 4.41Å; F89-I93 WeakPolarHBondContact O-CG1 3.34Å; F89-I93 PolarHBondContact O-N 2.96Å; F89-I93 VanDerWaalsContact O-N 3.11Å; L90-I93 PolarHBondContact O-N 3Å; L91-I93 VanDerWaalsContact C-N 3.27Å; L91-I93 PolarHBondContact O-N 3.16Å; I93-L96 PolarHBondContact O-N 2.75Å; I93-L97 PolarHBondContact O-N 2.93Å
94	I	96.3	Very high	95.2	Very high	2 Å²	2	29.2 Å²	29.2	1%	0.01	14%	0.141	C	C	.	.	H	α-helix	trans	-66.4	-42.6	179.2	-62.9	-170.9	0	0	0	110.8	L11 I12 C15 V24 L90 L91 L96 L97 L98	L11-I94 HydrophobicContact CB-CD1 3.73Å; I12-I94 HydrophobicContact CG1-CG2 3.96Å; C15-I94 WeakPolarHBondContact SG-CD1 3.37Å; V24-I94 HydrophobicContact CG1-CD1 3.92Å; L90-I94 WeakPolarHBondContact O-CG1 3.44Å; L90-I94 PolarHBondContact O-N 3.48Å; L91-I94 PolarHBondContact O-N 3.31Å; I94-L96 VanDerWaalsContact C-N 3.32Å; I94-L96 PolarHBondContact O-N 3.27Å; I94-L97 PolarHBondContact O-N 3.25Å; I94-L98 WeakPolarHBondContact O-CB 3.19Å; I94-L98 PolarHBondContact O-N 3.12Å
95	I	96.8	Very high	95.5	Very high	61 Å²	61	25 Å²	25	31%	0.313	12%	0.119	S	C	.	.	H	α-helix	trans	-60.3	-45.6	175.5	-68.3	172.3	0	0	0	110.1	L91 L97 L98 L99 P122	L91-I95 HydrophobicContact CD2-CD1 3.39Å; L91-I95 HydrophobicContact CD2-CG1 4.44Å; L91-I95 HydrophobicContact CG-CD1 3.83Å; L91-I95 HydrophobicContact CG-CG1 4.46Å; L91-I95 VanDerWaalsContact O-CG1 3.31Å; L91-I95 WeakPolarHBondContact O-CG1 3.31Å; L91-I95 PolarHBondContact O-N 2.98Å; I95-L97 PolarHBondContact O-N 3.4Å; I95-L98 PolarHBondContact O-N 3.41Å; I95-L99 HydrophobicContact CG2-CD1 4.1Å; I95-L99 HydrophobicContact CG2-CG 4.41Å; I95-L99 WeakPolarHBondContact O-CG 3.26Å; I95-L99 PolarHBondContact O-N 3.07Å; I95-P122 HydrophobicContact CG2-CG 3.89Å
96	L	97.2	Very high	95.7	Very high	0 Å²	0	16.6 Å²	16.6	0%	0	9%	0.085	C	C	.	.	H	α-helix	trans	-60.6	-46.2	177.5	-177.7	59.9	0	0	0	111.8	N92 I93 I94 L98 L99 L100 P122 T123 L126 I218	N92-L96 VanDerWaalsContact O-CB 3.27Å; N92-L96 WeakPolarHBondContact O-CB 3.49Å; N92-L96 PolarHBondContact O-N 3.23Å; I93-L96 PolarHBondContact O-N 2.75Å; I94-L96 VanDerWaalsContact C-N 3.32Å; I94-L96 PolarHBondContact O-N 3.27Å; L96-L98 VanDerWaalsContact C-N 3.33Å; L96-L98 PolarHBondContact O-N 3Å; L96-L99 PolarHBondContact O-N 3.46Å; L96-L100 HydrophobicContact CD1-CD1 4.18Å; L96-L100 HydrophobicContact CD1-CG 4.24Å; L96-L100 HydrophobicContact CG-CD1 3.95Å; L96-L100 HydrophobicContact CG-CG 4.43Å; L96-L100 WeakPolarHBondContact O-CB 3.45Å; L96-L100 VanDerWaalsContact O-CG 3.22Å; L96-L100 WeakPolarHBondContact O-CG 3.34Å; L96-L100 PolarHBondContact O-N 2.97Å; L96-P122 HydrophobicContact CB-CB 3.85Å; L96-P122 HydrophobicContact CB-CG 4.38Å; L96-P122 HydrophobicContact CD1-CB 4.11Å; L96-P122 HydrophobicContact CD1-CG 4.43Å; L96-P122 HydrophobicContact CG-CB 4.43Å; L96-T123 HydrophobicContact CD1-CG2 3.84Å; L96-T123 HydrophobicContact CD2-CG2 4.1Å; L96-L126 HydrophobicContact CD2-CD1 3.91Å; L96-I218 HydrophobicContact CD2-CB 4.47Å; L96-I218 HydrophobicContact CD2-CD1 3.33Å; L96-I218 HydrophobicContact CD2-CG1 4.24Å; L96-I218 HydrophobicContact CD2-CG2 3.81Å
97	L	97	Very high	95.7	Very high	0 Å²	0	15.6 Å²	15.6	0%	0	8%	0.082	C	C	.	.	H	α-helix	trans	-59.9	-45.1	176.2	177.3	66.3	0	0	0	111.3	L8 M28 L66 C69 I93 I94 I95 L99 L100 I101	L8-L97 HydrophobicContact CD1-CD2 3.84Å; L8-L97 HydrophobicContact CD1-CG 3.93Å; L8-L97 HydrophobicContact CD2-CD2 3.45Å; L8-L97 VanDerWaalsContact CD2-CD2 3.45Å; L8-L97 HydrophobicContact CD2-CG 4.38Å; L8-L97 HydrophobicContact CG-CD2 4.32Å; M28-L97 HydrophobicContact CE-CB 4.37Å; M28-L97 HydrophobicContact CE-CD2 3.17Å; M28-L97 HydrophobicContact CE-CG 4.31Å; M28-L97 HydrophobicContact SD-CD2 3.67Å; L66-L97 HydrophobicContact CD2-CD1 4.05Å; L66-L97 HydrophobicContact CD2-CD2 3.71Å; L66-L97 HydrophobicContact CD2-CG 4.36Å; L66-L97 HydrophobicContact CG-CD1 4.39Å; C69-L97 HydrophobicContact CB-CB 4.34Å; C69-L97 HydrophobicContact CB-CD1 4.07Å; I93-L97 PolarHBondContact O-N 2.93Å; I94-L97 PolarHBondContact O-N 3.25Å; I95-L97 PolarHBondContact O-N 3.4Å; L97-L99 VanDerWaalsContact C-N 3.33Å; L97-L99 PolarHBondContact O-N 3.42Å; L97-L100 PolarHBondContact O-N 3.42Å; L97-I101 HydrophobicContact CD1-CD1 4.03Å; L97-I101 HydrophobicContact CD1-CG1 4.04Å; L97-I101 HydrophobicContact CD2-CD1 4.47Å; L97-I101 HydrophobicContact CG-CD1 4.03Å; L97-I101 HydrophobicContact CG-CG1 4.34Å; L97-I101 WeakPolarHBondContact O-CG1 3.37Å; L97-I101 PolarHBondContact O-N 3.17Å
98	L	96.8	Very high	95.8	Very high	29 Å²	29	14.3 Å²	14.3	15%	0.152	8%	0.075	C	C	.	.	H	α-helix	trans	-58.9	-46	178.8	-179.7	141.2	0	0	0	111	L8 L9 I94 I95 L96 L100 I101 L102	L8-L98 HydrophobicContact CB-CD1 4.47Å; L8-L98 HydrophobicContact CD1-CB 4.46Å; L9-L98 HydrophobicContact CD2-CD1 3.65Å; L9-L98 HydrophobicContact CG-CD1 3.98Å; I94-L98 WeakPolarHBondContact O-CB 3.19Å; I94-L98 PolarHBondContact O-N 3.12Å; I95-L98 PolarHBondContact O-N 3.41Å; L96-L98 VanDerWaalsContact C-N 3.33Å; L96-L98 PolarHBondContact O-N 3Å; L98-L100 PolarHBondContact O-N 3.1Å; L98-I101 PolarHBondContact O-N 3.32Å; L98-L102 HydrophobicContact CD2-CD1 3.61Å; L98-L102 HydrophobicContact CG-CD1 4.28Å; L98-L102 VanDerWaalsContact O-CG 3.26Å; L98-L102 WeakPolarHBondContact O-CG 3.02Å; L98-L102 PolarHBondContact O-N 3.4Å
99	L	97.4	Very high	95.8	Very high	22 Å²	22	10 Å²	10	12%	0.115	5%	0.053	C	C	.	.	H	α-helix	trans	-62.4	-43.3	176.1	-66.9	176.7	0	0	0	111.6	I95 L96 L97 I101 L102 T103 F115 S118 P122	I95-L99 HydrophobicContact CG2-CD1 4.1Å; I95-L99 HydrophobicContact CG2-CG 4.41Å; I95-L99 WeakPolarHBondContact O-CG 3.26Å; I95-L99 PolarHBondContact O-N 3.07Å; L96-L99 PolarHBondContact O-N 3.46Å; L97-L99 VanDerWaalsContact C-N 3.33Å; L97-L99 PolarHBondContact O-N 3.42Å; L99-I101 PolarHBondContact O-N 2.82Å; L99-L102 PolarHBondContact O-N 2.97Å; L99-T103 WeakPolarHBondContact O-CG2 3.5Å; L99-T103 PolarHBondContact O-N 3Å; L99-F115 HydrophobicContact CD2-CD1 4.23Å; L99-S118 WeakPolarHBondContact CD1-O 3.45Å; L99-P122 HydrophobicContact CD1-CG 3.81Å
100	L	97	Very high	95.8	Very high	0 Å²	0	13.1 Å²	13.1	0%	0	7%	0.067	C	C	.	.	H	α-helix	trans	-63	-43.2	178.4	-70.3	171	0	0	0	112.2	L96 L97 L98 L102 T103 F104 I218 I222 M223 L226	L96-L100 HydrophobicContact CD1-CD1 4.18Å; L96-L100 HydrophobicContact CD1-CG 4.24Å; L96-L100 HydrophobicContact CG-CD1 3.95Å; L96-L100 HydrophobicContact CG-CG 4.43Å; L96-L100 WeakPolarHBondContact O-CB 3.45Å; L96-L100 VanDerWaalsContact O-CG 3.22Å; L96-L100 WeakPolarHBondContact O-CG 3.34Å; L96-L100 PolarHBondContact O-N 2.97Å; L97-L100 PolarHBondContact O-N 3.42Å; L98-L100 PolarHBondContact O-N 3.1Å; L100-L102 VanDerWaalsContact C-N 3.31Å; L100-L102 PolarHBondContact O-N 3.37Å; L100-T103 WeakPolarHBondContact CA-OG1 3.44Å; L100-T103 PolarHBondContact O-N 3.23Å; L100-T103 PolarHBondContact O-OG1 3.06Å; L100-F104 WeakPolarHBondContact O-CD2 3.45Å; L100-F104 PolarHBondContact O-N 3.18Å; L100-F104 VanDerWaalsContact O-N 3.14Å; L100-I218 HydrophobicContact CD1-CG2 4.48Å; L100-I222 HydrophobicContact CD1-CB 4.49Å; L100-I222 HydrophobicContact CD1-CD1 3.82Å; L100-I222 HydrophobicContact CD1-CG2 4.06Å; L100-I222 HydrophobicContact CD2-CG2 3.8Å; L100-I222 HydrophobicContact CG-CG2 4.45Å; L100-M223 HydrophobicContact CD2-SD 4.21Å; L100-L226 HydrophobicContact CD2-CD1 3.72Å; L100-L226 HydrophobicContact CD2-CD2 4.11Å; L100-L226 HydrophobicContact CD2-CG 4.21Å
101	I	96.1	Very high	95.8	Very high	0 Å²	0	15.3 Å²	15.3	0%	0	8%	0.077	C	C	.	.	H	α-helix	trans	-63.2	-41.1	175.9	-64.7	-178	0	0	0	110.7	M1 I4 L8 I62 L66 L97 L98 L99 T103 S105	M1-I101 HydrophobicContact CE-CG2 3.73Å; I4-I101 HydrophobicContact CG2-CD1 3.82Å; L8-I101 HydrophobicContact CD1-CD1 3.47Å; L8-I101 VanDerWaalsContact CD1-CD1 3.47Å; I62-I101 HydrophobicContact CG2-CG1 4.29Å; I62-I101 HydrophobicContact CG2-CG2 4.45Å; L66-I101 HydrophobicContact CD2-CD1 3.75Å; L66-I101 HydrophobicContact CG-CD1 4.12Å; L97-I101 HydrophobicContact CD1-CD1 4.03Å; L97-I101 HydrophobicContact CD1-CG1 4.04Å; L97-I101 HydrophobicContact CD2-CD1 4.47Å; L97-I101 HydrophobicContact CG-CD1 4.03Å; L97-I101 HydrophobicContact CG-CG1 4.34Å; L97-I101 WeakPolarHBondContact O-CG1 3.37Å; L97-I101 PolarHBondContact O-N 3.17Å; L98-I101 PolarHBondContact O-N 3.32Å; L99-I101 PolarHBondContact O-N 2.82Å; I101-T103 VanDerWaalsContact C-N 3.34Å; I101-T103 PolarHBondContact O-N 2.88Å; I101-S105 WeakPolarHBondContact O-CB 3.39Å; I101-S105 PolarHBondContact O-N 3.25Å; I101-S105 VanDerWaalsContact O-N 3.08Å; I101-S105 PolarHBondContact O-OG 2.96Å
102	L	96.3	Very high	95.8	Very high	17 Å²	17	13.8 Å²	13.8	9%	0.089	7%	0.069	C	C	.	.	H	α-helix	trans	-64.2	-36.4	175.2	-68.3	172.8	0	0	0	112.3	I5 F51 L52 L98 L99 L100 S106 F115	I5-L102 HydrophobicContact CD1-CD2 3.72Å; I5-L102 HydrophobicContact CG1-CD2 4.43Å; F51-L102 HydrophobicContact CE2-CD2 4.35Å; L52-L102 HydrophobicContact CD2-CD2 3.81Å; L98-L102 HydrophobicContact CD2-CD1 3.61Å; L98-L102 HydrophobicContact CG-CD1 4.28Å; L98-L102 VanDerWaalsContact O-CG 3.26Å; L98-L102 WeakPolarHBondContact O-CG 3.02Å; L98-L102 PolarHBondContact O-N 3.4Å; L99-L102 PolarHBondContact O-N 2.97Å; L100-L102 VanDerWaalsContact C-N 3.31Å; L100-L102 PolarHBondContact O-N 3.37Å; L102-S106 WeakPolarHBondContact O-CB 3.22Å; L102-S106 PolarHBondContact O-N 3.04Å; L102-F115 HydrophobicContact CB-CB 4.42Å; L102-F115 HydrophobicContact CB-CD1 3.93Å; L102-F115 HydrophobicContact CB-CD2 3.74Å; L102-F115 HydrophobicContact CB-CE1 4.08Å; L102-F115 HydrophobicContact CB-CE2 3.88Å; L102-F115 HydrophobicContact CB-CG 3.77Å; L102-F115 HydrophobicContact CB-CZ 4.05Å; L102-F115 HydrophobicContact CD1-CD1 4.09Å; L102-F115 HydrophobicContact CD1-CE1 3.64Å; L102-F115 HydrophobicContact CD1-CZ 3.91Å; L102-F115 HydrophobicContact CD2-CZ 4.47Å; L102-F115 HydrophobicContact CG-CE1 4.42Å; L102-F115 HydrophobicContact CG-CZ 4.37Å
103	T	96.6	Very high	95.8	Very high	0 Å²	0	13.6 Å²	13.6	0%	0	7%	0.067	C	C	.	.	H	α-helix	trans	-60.4	-55	174.6	58.7	0	0	0	0	111.8	L99 L100 I101 S105 S106 F115 F116 L226	L99-T103 WeakPolarHBondContact O-CG2 3.5Å; L99-T103 PolarHBondContact O-N 3Å; L100-T103 WeakPolarHBondContact CA-OG1 3.44Å; L100-T103 PolarHBondContact O-N 3.23Å; L100-T103 PolarHBondContact O-OG1 3.06Å; I101-T103 VanDerWaalsContact C-N 3.34Å; I101-T103 PolarHBondContact O-N 2.88Å; T103-S105 VanDerWaalsContact C-N 3.3Å; T103-S105 PolarHBondContact O-N 3.2Å; T103-S106 PolarHBondContact O-N 3.23Å; T103-S106 PolarHBondContact O-OG 3.29Å; T103-F115 HydrophobicContact CG2-CB 3.39Å; T103-F115 WeakPolarHBondContact CG2-O 3.48Å; T103-F116 HydrophobicContact CG2-CB 4.45Å; T103-L226 HydrophobicContact CG2-CD2 4.27Å; T103-L226 VanDerWaalsContact OG1-CD2 3.26Å; T103-L226 WeakPolarHBondContact OG1-CD2 3.39Å
104	F	95.1	Very high	95.8	Very high	0 Å²	0	17 Å²	17	0%	0	9%	0.085	C	C	.	.	H	α-helix	trans	-70.9	-27.1	-173.7	-66.2	-57	0	0	0	113	S58 L61 I62 L100 I222 L226 Y229	S58-F104 WeakPolarHBondContact CB-O 3.37Å; L61-F104 HydrophobicContact CB-CD1 3.76Å; L61-F104 HydrophobicContact CB-CD2 4.1Å; L61-F104 HydrophobicContact CB-CE1 3.76Å; L61-F104 HydrophobicContact CB-CE2 4.1Å; L61-F104 HydrophobicContact CB-CG 3.94Å; L61-F104 HydrophobicContact CB-CZ 3.94Å; L61-F104 HydrophobicContact CD1-CD1 3.78Å; L61-F104 HydrophobicContact CD1-CE1 3.56Å; L61-F104 HydrophobicContact CD1-CZ 4.36Å; L61-F104 HydrophobicContact CG-CD1 4.42Å; L61-F104 HydrophobicContact CG-CE1 4.2Å; I62-F104 HydrophobicContact CD1-CB 4.06Å; I62-F104 HydrophobicContact CG1-CB 3.56Å; I62-F104 HydrophobicContact CG1-CD2 4.35Å; I62-F104 HydrophobicContact CG1-CG 4.36Å; L100-F104 WeakPolarHBondContact O-CD2 3.45Å; L100-F104 PolarHBondContact O-N 3.18Å; L100-F104 VanDerWaalsContact O-N 3.14Å; F104-I222 HydrophobicContact CE2-CG2 3.66Å; F104-I222 HydrophobicContact CZ-CG2 3.72Å; F104-L226 HydrophobicContact CD1-CD2 4.31Å; F104-L226 HydrophobicContact CE1-CD2 3.55Å; F104-L226 HydrophobicContact CE1-CG 4.43Å; F104-L226 HydrophobicContact CE2-CD2 3.99Å; F104-L226 HydrophobicContact CZ-CD2 3.36Å; F104-L226 HydrophobicContact CZ-CG 4.04Å; F104-Y229 AromaticContact CD1-CD1 3.83Å; F104-Y229 HydrophobicContact CD1-CD1 3.83Å; F104-Y229 HydrophobicContact CD1-CD2 4.12Å; F104-Y229 HydrophobicContact CD1-CE1 4.18Å; F104-Y229 HydrophobicContact CD1-CE2 4.46Å; F104-Y229 AromaticContact CD1-CG 3.8Å; F104-Y229 HydrophobicContact CD1-CG 3.8Å; F104-Y229 HydrophobicContact CE1-CD1 4.23Å; F104-Y229 HydrophobicContact CE1-CG 4Å; F104-Y229 PolarHBondContact O-OH 3.31Å
105	S	94.6	Very high	95.8	Very high	0 Å²	0	18.3 Å²	18.3	0%	0	9%	0.091	C	C	.	.	H	α-helix	trans	-90.3	-6.7	179.9	59.5	0	0	0	0	114.8	L52 G53 I101 T103 M107	L52-S105 CarbonylContact C-O 3.59Å; L52-S105 VanDerWaalsContact CA-O 3.3Å; L52-S105 WeakPolarHBondContact CA-O 3.41Å; L52-S105 WeakPolarHBondContact CD2-OG 2.96Å; G53-S105 PolarHBondContact N-O 3.48Å; G53-S105 CarbonylContact O-C 3.59Å; G53-S105 VanDerWaalsContact O-CA 3.28Å; G53-S105 WeakPolarHBondContact O-CA 3.27Å; G53-S105 WeakPolarHBondContact O-CB 3.48Å; G53-S105 VanDerWaalsContact O-O 3.09Å; I101-S105 WeakPolarHBondContact O-CB 3.39Å; I101-S105 PolarHBondContact O-N 3.25Å; I101-S105 VanDerWaalsContact O-N 3.08Å; I101-S105 PolarHBondContact O-OG 2.96Å; T103-S105 VanDerWaalsContact C-N 3.3Å; T103-S105 PolarHBondContact O-N 3.2Å; S105-M107 PolarHBondContact O-N 3.49Å
106	S	94.9	Very high	95.7	Very high	0 Å²	0	15.4 Å²	15.4	0%	0	8%	0.076	C	C	.	.	B	Isolated β-bridge	trans	-69.2	126.9	-177.8	60	0	0	0	0	112.6	W45 L102 T103 F112 F170	W45-S106 WeakPolarHBondContact CH2-O 3.42Å; L102-S106 WeakPolarHBondContact O-CB 3.22Å; L102-S106 PolarHBondContact O-N 3.04Å; T103-S106 PolarHBondContact O-N 3.23Å; T103-S106 PolarHBondContact O-OG 3.29Å; S106-F112 WeakPolarHBondContact OG-CA 3.49Å; S106-F112 VanDerWaalsContact OG-CB 3.24Å; S106-F112 WeakPolarHBondContact OG-CB 3.15Å; S106-F170 WeakPolarHBondContact O-CE2 3.12Å
107	M	93	Very high	95.6	Very high	11 Å²	11	16.3 Å²	16.3	5%	0.054	8%	0.08	C	C	.	.			trans	-84.8	-25	176.5	-70.5	-77.1	-164	0	0	113.5	W45 I48 F51 S105 N169 F170 Y171	W45-M107 HydrophobicContact CB-CE 3.39Å; W45-M107 HydrophobicContact CB-SD 4.33Å; W45-M107 HydrophobicContact CD2-CE 3.42Å; W45-M107 VanDerWaalsContact CD2-CE 3.42Å; W45-M107 HydrophobicContact CD2-SD 3.24Å; W45-M107 VanDerWaalsContact CE2-SD 3.58Å; W45-M107 HydrophobicContact CE3-CE 3.29Å; W45-M107 HydrophobicContact CE3-CG 4.29Å; W45-M107 HydrophobicContact CE3-SD 3.21Å; W45-M107 HydrophobicContact CG-CE 3.59Å; W45-M107 HydrophobicContact CG-SD 3.85Å; W45-M107 HydrophobicContact CH2-SD 3.76Å; W45-M107 HydrophobicContact CZ2-SD 3.82Å; W45-M107 HydrophobicContact CZ3-CE 4.06Å; W45-M107 HydrophobicContact CZ3-CG 4.15Å; W45-M107 HydrophobicContact CZ3-SD 3.48Å; W45-M107 WeakPolarHBondContact CZ3-SD 3.48Å; I48-M107 HydrophobicContact CD1-CE 4.09Å; I48-M107 HydrophobicContact CG1-CE 3.78Å; I48-M107 HydrophobicContact CG2-CE 4.36Å; F51-M107 VanDerWaalsContact O-CB 3.31Å; F51-M107 WeakPolarHBondContact O-CB 3.33Å; F51-M107 WeakPolarHBondContact O-CG 3.45Å; F51-M107 PolarHBondContact O-N 3.48Å; S105-M107 PolarHBondContact O-N 3.49Å; M107-N169 CarbonylContact O-C 3.59Å; M107-N169 WeakPolarHBondContact O-CA 3.39Å; M107-F170 VanDerWaalsContact C-CD2 3.49Å; M107-F170 WeakPolarHBondContact O-CD2 3.34Å; M107-F170 PolarHBondContact O-N 3.21Å; M107-Y171 HydrophobicContact CE-CD2 4.48Å; M107-Y171 HydrophobicContact CE-CE2 3.72Å; M107-Y171 HydrophobicContact SD-CD2 3.78Å; M107-Y171 HydrophobicContact SD-CE2 3.54Å; M107-Y171 VanDerWaalsContact SD-CE2 3.54Å
108	S	94.2	Very high	95.6	Very high	13 Å²	13	17.7 Å²	17.7	9%	0.091	9%	0.09	C	C	.	.	B	Isolated β-bridge	trans	-103.7	134.2	-176.3	61.9	0	0	0	0	110.9	F110 M111 F112 M168	S108-F110 VanDerWaalsContact C-N 3.28Å; S108-F110 PolarHBondContact O-N 3.23Å; S108-M111 PolarHBondContact O-N 2.79Å; S108-M111 VanDerWaalsContact OG-CB 3.27Å; S108-M111 WeakPolarHBondContact OG-CB 3.44Å; S108-M111 WeakPolarHBondContact OG-CG 3.5Å; S108-F112 WeakPolarHBondContact O-CB 3.04Å; S108-F112 PolarHBondContact O-N 2.97Å; S108-M168 CarbonylContact C-O 3.59Å; S108-M168 VanDerWaalsContact CA-O 3.29Å; S108-M168 WeakPolarHBondContact CA-O 3.45Å
109	L	93.9	Very high	95.6	Very high	0 Å²	0	16.3 Å²	16.3	0%	0	8%	0.083	C	C	.	.	H	α-helix	trans	-63.7	-33.9	-174.2	-165.9	151.3	0	0	0	112.3	F112 Y113 I158 M168 F170 V234 F237	L109-F112 WeakPolarHBondContact O-CB 3.34Å; L109-Y113 PolarHBondContact O-N 3.09Å; L109-I158 HydrophobicContact CD2-CB 4.09Å; L109-I158 HydrophobicContact CD2-CD1 3.5Å; L109-I158 HydrophobicContact CD2-CG1 3.3Å; L109-I158 HydrophobicContact CD2-CG2 3.82Å; L109-M168 HydrophobicContact CB-SD 4.19Å; L109-M168 PolarHBondContact N-O 2.96Å; L109-F170 HydrophobicContact CB-CE1 3.96Å; L109-F170 HydrophobicContact CB-CZ 4.11Å; L109-F170 HydrophobicContact CD1-CD1 4.46Å; L109-F170 HydrophobicContact CD1-CE1 3.8Å; L109-F170 HydrophobicContact CG-CE1 3.92Å; L109-F170 HydrophobicContact CG-CZ 4.22Å; L109-V234 HydrophobicContact CD1-CG2 4.14Å; L109-F237 HydrophobicContact CD1-CE1 3.63Å; L109-F237 HydrophobicContact CD1-CZ 3.49Å; L109-F237 VanDerWaalsContact CD1-CZ 3.49Å
110	F	95.7	Very high	95.5	Very high	66 Å²	66	16 Å²	16	29%	0.289	8%	0.081	S	C	.	.	H	α-helix	trans	-66.1	-45.7	173.9	179.1	-103.5	0	0	0	112.8	S108 F112 Y113 L114 L155 I158 F159 M168	S108-F110 VanDerWaalsContact C-N 3.28Å; S108-F110 PolarHBondContact O-N 3.23Å; F110-F112 VanDerWaalsContact C-N 3.32Å; F110-F112 PolarHBondContact O-N 2.91Å; F110-Y113 WeakPolarHBondContact O-CB 3.48Å; F110-Y113 PolarHBondContact O-N 3.03Å; F110-L114 HydrophobicContact CD1-CD1 4Å; F110-L114 HydrophobicContact CE1-CD1 3.4Å; F110-L114 HydrophobicContact CE1-CG 4.12Å; F110-L114 HydrophobicContact CZ-CD1 3.75Å; F110-L114 HydrophobicContact CZ-CD2 4.3Å; F110-L114 HydrophobicContact CZ-CG 4.11Å; F110-L114 PolarHBondContact O-N 3.48Å; F110-L114 VanDerWaalsContact O-N 3.09Å; F110-L155 HydrophobicContact CD2-CD1 4.41Å; F110-L155 HydrophobicContact CE2-CD1 4.06Å; F110-I158 HydrophobicContact CB-CG2 4.19Å; F110-I158 HydrophobicContact CD2-CG2 4.38Å; F110-F159 HydrophobicContact CD2-CE1 4.25Å; F110-F159 AromaticContact CE2-CE1 3.93Å; F110-F159 HydrophobicContact CE2-CE1 3.93Å; F110-F159 AromaticContact CE2-CZ 3.95Å; F110-F159 HydrophobicContact CE2-CZ 3.95Å; F110-M168 HydrophobicContact CB-CG 4.48Å
111	M	95.4	Very high	95.4	Very high	47 Å²	47	20.6 Å²	20.6	23%	0.232	11%	0.105	C	C	.	.	H	α-helix	trans	-67.4	-37.7	177.7	-65.2	-60.4	-65.3	0	0	111.1	F51 S108 Y113 L114 F115	F51-M111 HydrophobicContact CE2-CE 4.3Å; F51-M111 HydrophobicContact CZ-CE 4.32Å; S108-M111 PolarHBondContact O-N 2.79Å; S108-M111 VanDerWaalsContact OG-CB 3.27Å; S108-M111 WeakPolarHBondContact OG-CB 3.44Å; S108-M111 WeakPolarHBondContact OG-CG 3.5Å; M111-Y113 VanDerWaalsContact C-N 3.32Å; M111-Y113 PolarHBondContact O-N 3.28Å; M111-L114 PolarHBondContact O-N 3.26Å; M111-L114 HydrophobicContact SD-CD1 4.14Å; M111-F115 HydrophobicContact CB-CD2 4.39Å; M111-F115 HydrophobicContact CB-CE2 4.1Å; M111-F115 HydrophobicContact CE-CE2 3.61Å; M111-F115 HydrophobicContact CE-CZ 3.54Å; M111-F115 WeakPolarHBondContact O-CD2 3.17Å; M111-F115 PolarHBondContact O-N 3.24Å
112	F	95.8	Very high	95.4	Very high	0 Å²	0	20.9 Å²	20.9	0%	0	11%	0.106	C	C	.	.	H	α-helix	trans	-53.7	-49.9	171.7	172.6	-107	0	0	0	111.3	S106 S108 L109 F110 L114 F115 F116 M154 F170 F191 Y229	S106-F112 WeakPolarHBondContact OG-CA 3.49Å; S106-F112 VanDerWaalsContact OG-CB 3.24Å; S106-F112 WeakPolarHBondContact OG-CB 3.15Å; S108-F112 WeakPolarHBondContact O-CB 3.04Å; S108-F112 PolarHBondContact O-N 2.97Å; L109-F112 WeakPolarHBondContact O-CB 3.34Å; F110-F112 VanDerWaalsContact C-N 3.32Å; F110-F112 PolarHBondContact O-N 2.91Å; F112-L114 PolarHBondContact O-N 3.4Å; F112-F115 PolarHBondContact O-N 2.84Å; F112-F116 HydrophobicContact CZ-CD2 4.22Å; F112-F116 WeakPolarHBondContact O-CB 3.28Å; F112-F116 PolarHBondContact O-N 3Å; F112-M154 HydrophobicContact CD1-CE 4.42Å; F112-M154 HydrophobicContact CE1-CE 4.38Å; F112-F170 HydrophobicContact CB-CE2 4.26Å; F112-F170 HydrophobicContact CB-CZ 4.09Å; F112-F170 HydrophobicContact CD1-CZ 4.37Å; F112-F170 HydrophobicContact CG-CZ 4.21Å; F112-F191 AromaticContact CE1-CE1 3.62Å; F112-F191 HydrophobicContact CE1-CE1 3.62Å; F112-F191 AromaticContact CE1-CZ 3.72Å; F112-F191 HydrophobicContact CE1-CZ 3.72Å; F112-F191 HydrophobicContact CZ-CE1 4.04Å; F112-F191 HydrophobicContact CZ-CZ 4.48Å; F112-Y229 HydrophobicContact CD2-CD1 4.35Å; F112-Y229 AromaticContact CD2-CE1 4Å; F112-Y229 HydrophobicContact CD2-CE1 4Å; F112-Y229 AromaticContact CE2-CD1 3.55Å; F112-Y229 HydrophobicContact CE2-CD1 3.55Å; F112-Y229 AromaticContact CE2-CE1 3.66Å; F112-Y229 HydrophobicContact CE2-CE1 3.66Å; F112-Y229 HydrophobicContact CZ-CD1 4.07Å; F112-Y229 HydrophobicContact CZ-CE1 4.47Å
113	Y	95.9	Very high	95.4	Very high	17 Å²	17	20.2 Å²	20.2	7%	0.067	10%	0.103	C	C	.	.	H	α-helix	trans	-58.9	-47	177.3	171.6	-91.5	0	0	0	112.8	L109 F110 M111 F115 F116 E117 S151 M154 L155 I158	L109-Y113 PolarHBondContact O-N 3.09Å; F110-Y113 WeakPolarHBondContact O-CB 3.48Å; F110-Y113 PolarHBondContact O-N 3.03Å; M111-Y113 VanDerWaalsContact C-N 3.32Å; M111-Y113 PolarHBondContact O-N 3.28Å; Y113-F115 PolarHBondContact O-N 2.98Å; Y113-F116 WeakPolarHBondContact O-CB 2.87Å; Y113-F116 PolarHBondContact O-N 3.19Å; Y113-E117 HydrophobicContact CD2-CG 4.35Å; Y113-E117 HydrophobicContact CE1-CG 4.26Å; Y113-E117 HydrophobicContact CE2-CG 3.84Å; Y113-E117 PolarHBondContact O-N 2.84Å; Y113-S151 VanDerWaalsContact CE2-O 3.31Å; Y113-S151 WeakPolarHBondContact CE2-O 3.21Å; Y113-S151 PolarHBondContact OH-O 3.49Å; Y113-M154 HydrophobicContact CD2-CE 4.13Å; Y113-M154 HydrophobicContact CD2-CG 4.28Å; Y113-M154 HydrophobicContact CD2-SD 3.84Å; Y113-M154 HydrophobicContact CE2-CB 4.48Å; Y113-M154 HydrophobicContact CE2-SD 4.4Å; Y113-L155 HydrophobicContact CD1-CD1 3.82Å; Y113-L155 HydrophobicContact CE1-CB 4.1Å; Y113-L155 HydrophobicContact CE1-CD1 3.6Å; Y113-L155 HydrophobicContact CE1-CG 4.26Å; Y113-L155 HydrophobicContact CE2-CB 4.24Å; Y113-I158 HydrophobicContact CD1-CD1 4.47Å; Y113-I158 HydrophobicContact CD2-CD1 4Å; Y113-I158 HydrophobicContact CG-CD1 3.74Å
114	L	96.4	Very high	95.3	Very high	73 Å²	73	21.7 Å²	21.7	38%	0.382	11%	0.111	S	C	.	.	H	α-helix	trans	-60.2	-45.5	179.5	-71.9	178.2	0	0	0	112.1	F110 M111 F112 F116 S118	F110-L114 HydrophobicContact CD1-CD1 4Å; F110-L114 HydrophobicContact CE1-CD1 3.4Å; F110-L114 HydrophobicContact CE1-CG 4.12Å; F110-L114 HydrophobicContact CZ-CD1 3.75Å; F110-L114 HydrophobicContact CZ-CD2 4.3Å; F110-L114 HydrophobicContact CZ-CG 4.11Å; F110-L114 PolarHBondContact O-N 3.48Å; F110-L114 VanDerWaalsContact O-N 3.09Å; M111-L114 PolarHBondContact O-N 3.26Å; M111-L114 HydrophobicContact SD-CD1 4.14Å; F112-L114 PolarHBondContact O-N 3.4Å; L114-F116 VanDerWaalsContact C-N 3.35Å; L114-S118 VanDerWaalsContact O-CB 3.3Å; L114-S118 WeakPolarHBondContact O-CB 3.37Å; L114-S118 PolarHBondContact O-N 3.43Å; L114-S118 PolarHBondContact O-OG 3.43Å
115	F	96.3	Very high	95.4	Very high	28 Å²	28	26.5 Å²	26.5	12%	0.123	13%	0.132	C	C	.	.	H	α-helix	trans	-69.9	-35.4	178	-62.9	-50.6	0	0	0	112.1	F51 L99 L102 T103 M111 F112 Y113 S118 S119	F51-F115 HydrophobicContact CD2-CE2 4.47Å; F51-F115 AromaticContact CE2-CE2 3.72Å; F51-F115 HydrophobicContact CE2-CE2 3.72Å; F51-F115 HydrophobicContact CE2-CZ 4.11Å; F51-F115 HydrophobicContact CZ-CE2 4.37Å; F51-F115 HydrophobicContact CZ-CZ 4.31Å; L99-F115 HydrophobicContact CD2-CD1 4.23Å; L102-F115 HydrophobicContact CB-CB 4.42Å; L102-F115 HydrophobicContact CB-CD1 3.93Å; L102-F115 HydrophobicContact CB-CD2 3.74Å; L102-F115 HydrophobicContact CB-CE1 4.08Å; L102-F115 HydrophobicContact CB-CE2 3.88Å; L102-F115 HydrophobicContact CB-CG 3.77Å; L102-F115 HydrophobicContact CB-CZ 4.05Å; L102-F115 HydrophobicContact CD1-CD1 4.09Å; L102-F115 HydrophobicContact CD1-CE1 3.64Å; L102-F115 HydrophobicContact CD1-CZ 3.91Å; L102-F115 HydrophobicContact CD2-CZ 4.47Å; L102-F115 HydrophobicContact CG-CE1 4.42Å; L102-F115 HydrophobicContact CG-CZ 4.37Å; T103-F115 HydrophobicContact CG2-CB 3.39Å; T103-F115 WeakPolarHBondContact CG2-O 3.48Å; M111-F115 HydrophobicContact CB-CD2 4.39Å; M111-F115 HydrophobicContact CB-CE2 4.1Å; M111-F115 HydrophobicContact CE-CE2 3.61Å; M111-F115 HydrophobicContact CE-CZ 3.54Å; M111-F115 WeakPolarHBondContact O-CD2 3.17Å; M111-F115 PolarHBondContact O-N 3.24Å; F112-F115 PolarHBondContact O-N 2.84Å; Y113-F115 PolarHBondContact O-N 2.98Å; F115-S118 VanDerWaalsContact CA-OG 3.23Å; F115-S118 WeakPolarHBondContact CA-OG 3.37Å; F115-S118 PolarHBondContact O-N 3.17Å; F115-S118 PolarHBondContact O-OG 3.18Å; F115-S118 VanDerWaalsContact O-OG 3.06Å; F115-S119 WeakPolarHBondContact O-CB 3.33Å; F115-S119 PolarHBondContact O-N 3.43Å
116	F	95.1	Very high	95.4	Very high	0 Å²	0	26.5 Å²	26.5	0%	0	13%	0.132	C	C	.	.	H	α-helix	trans	-63.8	-45.3	178.7	170	-96.9	0	0	0	111.8	T103 F112 Y113 L114 S119 F191 K194 L226	T103-F116 HydrophobicContact CG2-CB 4.45Å; F112-F116 HydrophobicContact CZ-CD2 4.22Å; F112-F116 WeakPolarHBondContact O-CB 3.28Å; F112-F116 PolarHBondContact O-N 3Å; Y113-F116 WeakPolarHBondContact O-CB 2.87Å; Y113-F116 PolarHBondContact O-N 3.19Å; L114-F116 VanDerWaalsContact C-N 3.35Å; F116-S119 PolarHBondContact O-OG 3.12Å; F116-F191 HydrophobicContact CE2-CD1 4.27Å; F116-F191 HydrophobicContact CE2-CE1 4.3Å; F116-F191 HydrophobicContact CZ-CD1 4.05Å; F116-F191 HydrophobicContact CZ-CE1 4.17Å; F116-K194 HydrophobicContact CE1-CG 4.38Å; F116-K194 HydrophobicContact CE2-CD 4.35Å; F116-K194 HydrophobicContact CE2-CG 3.89Å; F116-K194 HydrophobicContact CZ-CB 4.45Å; F116-K194 HydrophobicContact CZ-CD 4.04Å; F116-K194 HydrophobicContact CZ-CG 3.43Å; F116-K194 VanDerWaalsContact CZ-CG 3.43Å; F116-L226 HydrophobicContact CD2-CB 4.03Å; F116-L226 HydrophobicContact CE2-CB 4.02Å
117	E	95.1	Very high	95.4	Very high	20 Å²	20	26.6 Å²	26.6	9%	0.093	13%	0.132	C	C	.	.	H	α-helix	trans	-73.9	-39.9	175.9	-70.6	-56.6	129.7	0	0	112.2	Y113 S119 L120 L148 S151	Y113-E117 HydrophobicContact CD2-CG 4.35Å; Y113-E117 HydrophobicContact CE1-CG 4.26Å; Y113-E117 HydrophobicContact CE2-CG 3.84Å; Y113-E117 PolarHBondContact O-N 2.84Å; E117-S119 PolarHBondContact O-N 3.37Å; E117-L120 VanDerWaalsContact O-CB 3.23Å; E117-L120 WeakPolarHBondContact O-CB 3.46Å; E117-L120 PolarHBondContact O-N 3.22Å; E117-L120 VanDerWaalsContact OE2-CD1 3.29Å; E117-L120 WeakPolarHBondContact OE2-CD1 3.17Å; E117-L148 WeakPolarHBondContact OE2-CD2 3.12Å; E117-S151 WeakPolarHBondContact OE1-CB 3.2Å; E117-S151 PolarHBondContact OE1-OG 3.08Å; E117-S151 PolarHBondContact OE2-OG 2.83Å; E117-S151 VanDerWaalsContact OE2-OG 3.1Å
118	S	95.9	Very high	95.5	Very high	29 Å²	29	28.4 Å²	28.4	20%	0.203	14%	0.142	C	C	.	.	H	α-helix	trans	-64	-29.1	177.8	56.8	0	0	0	0	113.1	L99 L114 F115 L120 I121 P122	L99-S118 WeakPolarHBondContact CD1-O 3.45Å; L114-S118 VanDerWaalsContact O-CB 3.3Å; L114-S118 WeakPolarHBondContact O-CB 3.37Å; L114-S118 PolarHBondContact O-N 3.43Å; L114-S118 PolarHBondContact O-OG 3.43Å; F115-S118 VanDerWaalsContact CA-OG 3.23Å; F115-S118 WeakPolarHBondContact CA-OG 3.37Å; F115-S118 PolarHBondContact O-N 3.17Å; F115-S118 PolarHBondContact O-OG 3.18Å; F115-S118 VanDerWaalsContact O-OG 3.06Å; S118-L120 PolarHBondContact O-N 3.12Å; S118-L120 VanDerWaalsContact O-N 3.15Å; S118-I121 PolarHBondContact O-N 3.25Å; S118-P122 WeakPolarHBondContact O-CD 3.4Å
119	S	96.6	Very high	95.5	Very high	0 Å²	0	29.9 Å²	29.9	0%	0	16%	0.159	C	C	.	.	T	Hydrogen-bonded Turn	trans	-58.7	-24.6	173.8	76	0	0	0	0	113.3	F115 F116 E117 I121 P122 T123	F115-S119 WeakPolarHBondContact O-CB 3.33Å; F115-S119 PolarHBondContact O-N 3.43Å; F116-S119 PolarHBondContact O-OG 3.12Å; E117-S119 PolarHBondContact O-N 3.37Å; S119-I121 VanDerWaalsContact C-N 3.31Å; S119-I121 PolarHBondContact O-N 3Å; S119-P122 WeakPolarHBondContact O-CD 3.47Å; S119-T123 WeakPolarHBondContact O-CG2 3.44Å
120	L	95	Very high	95.5	Very high	15 Å²	15	31.5 Å²	31.5	8%	0.079	17%	0.165	C	C	.	.	H	α-helix	trans	-65.2	-34.5	175.5	-71.4	169.3	0	0	0	112.4	E117 S118 T123 L124 L143 T147 K194 M223	E117-L120 VanDerWaalsContact O-CB 3.23Å; E117-L120 WeakPolarHBondContact O-CB 3.46Å; E117-L120 PolarHBondContact O-N 3.22Å; E117-L120 VanDerWaalsContact OE2-CD1 3.29Å; E117-L120 WeakPolarHBondContact OE2-CD1 3.17Å; S118-L120 PolarHBondContact O-N 3.12Å; S118-L120 VanDerWaalsContact O-N 3.15Å; L120-T123 WeakPolarHBondContact CA-OG1 3.07Å; L120-T123 PolarHBondContact O-N 3.32Å; L120-T123 PolarHBondContact O-OG1 2.89Å; L120-L124 WeakPolarHBondContact O-CB 3.22Å; L120-L124 PolarHBondContact O-N 3.42Å; L120-L143 HydrophobicContact CD2-CG 4.44Å; L120-T147 HydrophobicContact CD1-CG2 4.46Å; L120-T147 WeakPolarHBondContact CD1-OG1 3.36Å; L120-T147 HydrophobicContact CD2-CG2 4.28Å; L120-K194 VanDerWaalsContact CG-NZ 3.29Å; L120-M223 HydrophobicContact CD2-CE 4.05Å
121	I	95.9	Very high	95.3	Very high	97 Å²	97	28.6 Å²	28.6	50%	0.497	15%	0.154	S	C	.	.	H	α-helix	trans	-63.4	-52	-173	-59.9	166.1	0	0	0	110.9	S118 S119 T123 L124 F125	S118-I121 PolarHBondContact O-N 3.25Å; S119-I121 VanDerWaalsContact C-N 3.31Å; S119-I121 PolarHBondContact O-N 3Å; I121-T123 VanDerWaalsContact C-N 3.31Å; I121-T123 PolarHBondContact O-N 3.08Å; I121-L124 PolarHBondContact O-N 3.04Å; I121-F125 HydrophobicContact CG2-CD2 4.21Å; I121-F125 HydrophobicContact CG2-CE2 3.65Å; I121-F125 HydrophobicContact CG2-CZ 4.03Å; I121-F125 PolarHBondContact O-N 3.07Å
122	P	95.9	Very high	94.9	Very high	5 Å²	5	31.1 Å²	31.1	3%	0.032	16%	0.162	C	C	.	.	H	α-helix	trans	-63.4	-34	174.5	-22.5	33.2	0	0	0	113.5	I95 L96 L99 S118 S119 L124 F125 L126	I95-P122 HydrophobicContact CG2-CG 3.89Å; L96-P122 HydrophobicContact CB-CB 3.85Å; L96-P122 HydrophobicContact CB-CG 4.38Å; L96-P122 HydrophobicContact CD1-CB 4.11Å; L96-P122 HydrophobicContact CD1-CG 4.43Å; L96-P122 HydrophobicContact CG-CB 4.43Å; L99-P122 HydrophobicContact CD1-CG 3.81Å; S118-P122 WeakPolarHBondContact O-CD 3.4Å; S119-P122 WeakPolarHBondContact O-CD 3.47Å; P122-L124 VanDerWaalsContact C-N 3.32Å; P122-L124 PolarHBondContact O-N 3.3Å; P122-F125 PolarHBondContact O-N 2.64Å; P122-L126 WeakPolarHBondContact O-CG 3.45Å; P122-L126 PolarHBondContact O-N 3.19Å
123	T	96	Very high	94.7	Very high	4 Å²	4	33.9 Å²	33.9	3%	0.025	18%	0.175	C	C	.	.	H	α-helix	trans	-65.2	-38.2	176.6	62.6	0	0	0	0	112.2	L96 S119 L120 I121 L126 I127 M223	L96-T123 HydrophobicContact CD1-CG2 3.84Å; L96-T123 HydrophobicContact CD2-CG2 4.1Å; S119-T123 WeakPolarHBondContact O-CG2 3.44Å; L120-T123 WeakPolarHBondContact CA-OG1 3.07Å; L120-T123 PolarHBondContact O-N 3.32Å; L120-T123 PolarHBondContact O-OG1 2.89Å; I121-T123 VanDerWaalsContact C-N 3.31Å; I121-T123 PolarHBondContact O-N 3.08Å; T123-L126 PolarHBondContact O-N 3.36Å; T123-I127 WeakPolarHBondContact O-CG1 3.39Å; T123-I127 PolarHBondContact O-N 3.4Å; T123-I127 VanDerWaalsContact O-N 3.1Å; T123-M223 HydrophobicContact CG2-CE 3.89Å; T123-M223 HydrophobicContact CG2-CG 4.16Å; T123-M223 HydrophobicContact CG2-SD 3.86Å
124	L	95.5	Very high	94.5	Very high	30 Å²	30	38.3 Å²	38.3	16%	0.157	21%	0.206	C	C	.	.	H	α-helix	trans	-64.2	-42.5	174.2	179.9	141.3	0	0	0	111	L120 I121 P122 L126 I127 L128 L144	L120-L124 WeakPolarHBondContact O-CB 3.22Å; L120-L124 PolarHBondContact O-N 3.42Å; I121-L124 PolarHBondContact O-N 3.04Å; P122-L124 VanDerWaalsContact C-N 3.32Å; P122-L124 PolarHBondContact O-N 3.3Å; L124-L126 VanDerWaalsContact C-N 3.32Å; L124-L126 PolarHBondContact O-N 2.91Å; L124-I127 PolarHBondContact O-N 3.3Å; L124-L128 HydrophobicContact CD2-CD1 3.49Å; L124-L128 VanDerWaalsContact CD2-CD1 3.49Å; L124-L128 HydrophobicContact CD2-CG 4.24Å; L124-L128 HydrophobicContact CG-CD1 3.95Å; L124-L128 HydrophobicContact CG-CG 4.29Å; L124-L128 WeakPolarHBondContact O-CB 3.44Å; L124-L128 WeakPolarHBondContact O-CG 3.26Å; L124-L128 PolarHBondContact O-N 3.48Å; L124-L144 HydrophobicContact CD1-CB 4.04Å; L124-L144 HydrophobicContact CD1-CD1 3.59Å; L124-L144 HydrophobicContact CD1-CG 4.45Å
125	F	95.6	Very high	94.3	Very high	102 Å²	102	40.3 Å²	40.3	45%	0.447	21%	0.213	S	C	.	.	H	α-helix	trans	-63	-35.8	173.7	-67.5	-33.6	0	0	0	113.2	I121 P122 G129	I121-F125 HydrophobicContact CG2-CD2 4.21Å; I121-F125 HydrophobicContact CG2-CE2 3.65Å; I121-F125 HydrophobicContact CG2-CZ 4.03Å; I121-F125 PolarHBondContact O-N 3.07Å; P122-F125 PolarHBondContact O-N 2.64Å; F125-G129 WeakPolarHBondContact O-CA 3.3Å; F125-G129 PolarHBondContact O-N 2.95Å
126	L	95.4	Very high	94.2	Very high	0 Å²	0	42.6 Å²	42.6	0%	0	22%	0.221	C	C	.	.	H	α-helix	trans	-62.9	-44.1	174.6	-73.5	172.5	0	0	0	112	M72 F89 L96 P122 T123 L124 W130 P212 I218	M72-L126 HydrophobicContact CE-CD1 4.39Å; F89-L126 HydrophobicContact CD2-CD2 3.87Å; F89-L126 HydrophobicContact CE2-CD2 3.63Å; L96-L126 HydrophobicContact CD2-CD1 3.91Å; P122-L126 WeakPolarHBondContact O-CG 3.45Å; P122-L126 PolarHBondContact O-N 3.19Å; T123-L126 PolarHBondContact O-N 3.36Å; L124-L126 VanDerWaalsContact C-N 3.32Å; L124-L126 PolarHBondContact O-N 2.91Å; L126-W130 HydrophobicContact CD2-CE3 4.07Å; L126-W130 HydrophobicContact CD2-CZ3 4.03Å; L126-W130 PolarHBondContact O-N 3.03Å; L126-P212 WeakPolarHBondContact O-CD 3.29Å; L126-P212 WeakPolarHBondContact O-CG 3.09Å; L126-I218 HydrophobicContact CD1-CD1 3.6Å
127	I	95.6	Very high	94.2	Very high	1 Å²	1	47.8 Å²	47.8	1%	0.005	25%	0.248	C	C	.	.	H	α-helix	trans	-68	-50.6	179.4	-62.8	167.1	0	0	0	110.9	T123 L124 G131 R136 L143 A211 L219	T123-I127 WeakPolarHBondContact O-CG1 3.39Å; T123-I127 PolarHBondContact O-N 3.4Å; T123-I127 VanDerWaalsContact O-N 3.1Å; L124-I127 PolarHBondContact O-N 3.3Å; I127-G131 WeakPolarHBondContact O-CA 3.11Å; I127-G131 PolarHBondContact O-N 3.22Å; I127-R136 HydrophobicContact CG2-CB 4.32Å; I127-L143 HydrophobicContact CD1-CD2 3.75Å; I127-A211 HydrophobicContact CG1-CB 4.06Å; I127-L219 HydrophobicContact CD1-CD1 4.34Å
128	L	94.9	Very high	94.2	Very high	49 Å²	49	51.2 Å²	51.2	26%	0.257	26%	0.264	S	S	.	.	H	α-helix	trans	-71.3	-37.7	-175.8	-65.3	-173.7	0	0	0	113	L124 R136 L137	L124-L128 HydrophobicContact CD2-CD1 3.49Å; L124-L128 VanDerWaalsContact CD2-CD1 3.49Å; L124-L128 HydrophobicContact CD2-CG 4.24Å; L124-L128 HydrophobicContact CG-CD1 3.95Å; L124-L128 HydrophobicContact CG-CG 4.29Å; L124-L128 WeakPolarHBondContact O-CB 3.44Å; L124-L128 WeakPolarHBondContact O-CG 3.26Å; L124-L128 PolarHBondContact O-N 3.48Å; L128-R136 PolarHBondContact O-NE 3.33Å; L128-R136 PolarHBondContact O-NH1 3.5Å; L128-R136 PolarHBondContact O-NH2 3.12Å; L128-L137 HydrophobicContact CD2-CD2 3.84Å; L128-L137 HydrophobicContact CD2-CG 4.47Å
129	G	92.5	Very high	94.1	Very high	44 Å²	44	50 Å²	50	45%	0.454	26%	0.255	S	S	.	.	H	α-helix	trans	-72.2	-55.1	-177.6	0	0	0	0	0	112.6	F125 R136	F125-G129 WeakPolarHBondContact O-CA 3.3Å; F125-G129 PolarHBondContact O-N 2.95Å; G129-R136 PolarHBondContact O-NH1 2.98Å
130	W	94	Very high	94	Very high	35 Å²	35	50 Å²	50	13%	0.133	26%	0.256	C	S	.	.	H	α-helix	trans	-113.6	6.4	-168.6	-59.5	-91.3	0	0	0	114.6	I79 N84 L88 F89 N92 L126 P212	I79-W130 HydrophobicContact CD1-CB 4.33Å; I79-W130 HydrophobicContact CD1-CG 4.05Å; N84-W130 PolarHBondContact O-NE1 3.36Å; N84-W130 VanDerWaalsContact O-NE1 3.07Å; L88-W130 HydrophobicContact CB-CH2 4.46Å; L88-W130 HydrophobicContact CB-CZ2 4.38Å; F89-W130 VanDerWaalsContact CA-CH2 3.49Å; F89-W130 HydrophobicContact CB-CH2 3.95Å; F89-W130 HydrophobicContact CB-CZ2 3.37Å; F89-W130 AromaticContact CD2-CD2 3.66Å; F89-W130 HydrophobicContact CD2-CD2 3.66Å; F89-W130 AromaticContact CD2-CE2 3.67Å; F89-W130 AromaticContact CD2-CE3 3.89Å; F89-W130 HydrophobicContact CD2-CE3 3.89Å; F89-W130 HydrophobicContact CD2-CG 4.21Å; F89-W130 HydrophobicContact CD2-CH2 4.13Å; F89-W130 AromaticContact CD2-CZ2 3.93Å; F89-W130 HydrophobicContact CD2-CZ2 3.93Å; F89-W130 HydrophobicContact CD2-CZ3 4.11Å; F89-W130 HydrophobicContact CE2-CD2 4.4Å; F89-W130 HydrophobicContact CG-CZ2 4.14Å; N92-W130 WeakPolarHBondContact ND2-CH2 2.83Å; N92-W130 WeakPolarHBondContact ND2-CZ3 3.42Å; L126-W130 HydrophobicContact CD2-CE3 4.07Å; L126-W130 HydrophobicContact CD2-CZ3 4.03Å; L126-W130 PolarHBondContact O-N 3.03Å; W130-P212 HydrophobicContact CB-CB 4.12Å; W130-P212 HydrophobicContact CB-CG 4.05Å
131	G	92.1	Very high	94	Very high	5 Å²	5	53.9 Å²	53.9	5%	0.052	28%	0.276	C	S	.	.			trans	-64.1	148.3	172.3	0	0	0	0	0	112.4	I127 R136 E210	I127-G131 WeakPolarHBondContact O-CA 3.11Å; I127-G131 PolarHBondContact O-N 3.22Å; G131-R136 WeakPolarHBondContact O-CD 3.23Å; G131-R136 PolarHBondContact O-NH1 2.96Å; G131-E210 VanDerWaalsContact CA-O 3.28Å; G131-E210 WeakPolarHBondContact CA-O 3.28Å
132	Y	86.6	Confident	93.9	Very high	99 Å²	99	52.8 Å²	52.8	39%	0.388	27%	0.266	S	S	.	.	S	Bend	trans	-83.5	-38.2	-168.8	-62.7	-79	0	0	0	114.4	Y322	Y132-Y322 HydrophobicContact CD1-CE1 4.21Å; Y132-Y322 HydrophobicContact CD2-CE1 4.33Å; Y132-Y322 HydrophobicContact CE1-CE1 4.07Å; Y132-Y322 HydrophobicContact CE2-CE1 4.2Å; Y132-Y322 HydrophobicContact CG-CE1 4.34Å
133	Q	91.4	Very high	93.7	Very high	59 Å²	59	52.8 Å²	52.8	28%	0.276	27%	0.266	S	S	.	.	S	Bend	trans	-109.2	160.5	-171.4	-36.3	-168.9	-42.8	0	0	111.8	E135 R136 E210 R328	Q133-E135 PolarHBondContact O-N 3.2Å; Q133-R136 WeakPolarHBondContact O-CB 3.36Å; Q133-R136 VanDerWaalsContact O-CD 3.29Å; Q133-R136 WeakPolarHBondContact O-CD 3.4Å; Q133-R136 WeakPolarHBondContact O-CG 3.11Å; Q133-R136 PolarHBondContact O-N 3.48Å; Q133-E210 WeakPolarHBondContact CB-OE2 2.98Å; Q133-E210 VanDerWaalsContact CG-OE2 3.32Å; Q133-E210 WeakPolarHBondContact CG-OE2 3.21Å; Q133-E210 PolarHBondContact OE1-OE1 2.96Å; Q133-R328 VanDerWaalsContact CD-CZ 3.41Å; Q133-R328 VanDerWaalsContact CD-NH1 3.28Å; Q133-R328 VanDerWaalsContact NE2-CZ 3.3Å
134	P	92	Very high	93.6	Very high	110 Å²	110	55.2 Å²	55.2	71%	0.714	28%	0.278	S	S	*	.	T	Hydrogen-bonded Turn	trans	-61.6	-27.8	179.5	23.6	-35.3	0	0	0	113.7	R136 L137	P134-R136 PolarHBondContact O-N 3.43Å; P134-L137 PolarHBondContact O-N 3.14Å
135	E	92.9	Very high	93.6	Very high	114 Å²	114	59 Å²	59	53%	0.533	29%	0.294	S	S	.	.	T	Hydrogen-bonded Turn	trans	-61.6	-13.2	178.4	-63.5	-178.5	-167.7	0	0	113.4	Q133 L137 Q138 A139 E210	Q133-E135 PolarHBondContact O-N 3.2Å; E135-L137 PolarHBondContact O-N 3.26Å; E135-L137 VanDerWaalsContact O-N 3.14Å; E135-Q138 WeakPolarHBondContact O-CB 3.35Å; E135-Q138 PolarHBondContact O-N 3.21Å; E135-A139 PolarHBondContact O-N 3.29Å; E135-E210 HydrophobicContact CB-CG 4.07Å
136	R	94.3	Very high	93.4	Very high	77 Å²	77	57.5 Å²	57.5	29%	0.291	29%	0.285	S	S	.	.	H	α-helix	trans	-52.7	-33.1	173.4	72.9	-170.2	179.5	161.4	10.2	113.7	I127 L128 G129 G131 Q133 P134 G140 E210	I127-R136 HydrophobicContact CG2-CB 4.32Å; L128-R136 PolarHBondContact O-NE 3.33Å; L128-R136 PolarHBondContact O-NH1 3.5Å; L128-R136 PolarHBondContact O-NH2 3.12Å; G129-R136 PolarHBondContact O-NH1 2.98Å; G131-R136 WeakPolarHBondContact O-CD 3.23Å; G131-R136 PolarHBondContact O-NH1 2.96Å; Q133-R136 WeakPolarHBondContact O-CB 3.36Å; Q133-R136 VanDerWaalsContact O-CD 3.29Å; Q133-R136 WeakPolarHBondContact O-CD 3.4Å; Q133-R136 WeakPolarHBondContact O-CG 3.11Å; Q133-R136 PolarHBondContact O-N 3.48Å; P134-R136 PolarHBondContact O-N 3.43Å; R136-G140 PolarHBondContact O-N 3.37Å; R136-E210 HydrophobicContact CB-CB 4.2Å
137	L	93.8	Very high	93.3	Very high	109 Å²	109	57.7 Å²	57.7	57%	0.571	29%	0.287	S	S	*	.	H	α-helix	trans	-65.5	-48.1	176.1	-73.5	165.2	0	0	0	110.8	L128 P134 E135 A139 G140 L141	L128-L137 HydrophobicContact CD2-CD2 3.84Å; L128-L137 HydrophobicContact CD2-CG 4.47Å; P134-L137 PolarHBondContact O-N 3.14Å; E135-L137 PolarHBondContact O-N 3.26Å; E135-L137 VanDerWaalsContact O-N 3.14Å; L137-A139 PolarHBondContact O-N 2.93Å; L137-G140 PolarHBondContact O-N 3.29Å; L137-L141 WeakPolarHBondContact O-CG 3.21Å; L137-L141 PolarHBondContact O-N 2.87Å
138	Q	95.6	Very high	93.2	Very high	92 Å²	92	60.7 Å²	60.7	43%	0.43	30%	0.303	S	S	.	.	H	α-helix	trans	-64.7	-41.4	178.3	-165.7	-172.6	-3.9	0	0	111.1	E135 L141 Y142	E135-Q138 WeakPolarHBondContact O-CB 3.35Å; E135-Q138 PolarHBondContact O-N 3.21Å; Q138-L141 PolarHBondContact O-N 3.46Å; Q138-Y142 HydrophobicContact CG-CD2 4.05Å; Q138-Y142 HydrophobicContact CG-CE2 3.49Å; Q138-Y142 VanDerWaalsContact CG-CE2 3.49Å; Q138-Y142 PolarHBondContact NE2-OH 2.92Å; Q138-Y142 WeakPolarHBondContact O-CD2 3.35Å; Q138-Y142 PolarHBondContact O-N 3.48Å
139	A	94.5	Very high	93.1	Very high	2 Å²	2	64 Å²	64	2%	0.017	32%	0.319	C	S	.	.	H	α-helix	trans	-62.5	-43.2	175.6	0	0	0	0	0	112.3	E135 L137 Y142 L143 K206 E210	E135-A139 PolarHBondContact O-N 3.29Å; L137-A139 PolarHBondContact O-N 2.93Å; A139-Y142 PolarHBondContact O-N 3.13Å; A139-L143 PolarHBondContact O-N 3.21Å; A139-K206 HydrophobicContact CB-CB 4.21Å; A139-E210 HydrophobicContact CB-CB 4.04Å; A139-E210 HydrophobicContact CB-CG 4.18Å
140	G	94.3	Very high	93.1	Very high	1 Å²	1	63.6 Å²	63.6	1%	0.01	31%	0.309	C	S	.	.	H	α-helix	trans	-61.8	-40.9	175.3	0	0	0	0	0	112.8	R136 L137 L143 L144	R136-G140 PolarHBondContact O-N 3.37Å; L137-G140 PolarHBondContact O-N 3.29Å; G140-L143 PolarHBondContact O-N 3.08Å; G140-L144 WeakPolarHBondContact O-CB 3.49Å; G140-L144 PolarHBondContact O-N 3.4Å; G140-L144 VanDerWaalsContact O-N 3.07Å
141	L	94.5	Very high	93	Very high	97 Å²	97	62 Å²	62	51%	0.508	30%	0.303	S	S	.	.	H	α-helix	trans	-65.6	-42.9	175.2	-68.8	173.1	0	0	0	112	L137 Q138 L144 F145	L137-L141 WeakPolarHBondContact O-CG 3.21Å; L137-L141 PolarHBondContact O-N 2.87Å; Q138-L141 PolarHBondContact O-N 3.46Å; L141-L144 PolarHBondContact O-N 3.4Å; L141-F145 HydrophobicContact CB-CD2 4.38Å; L141-F145 HydrophobicContact CB-CE2 4.48Å; L141-F145 HydrophobicContact CD2-CE2 4.11Å; L141-F145 VanDerWaalsContact O-CD2 3.23Å; L141-F145 WeakPolarHBondContact O-CD2 3.43Å; L141-F145 PolarHBondContact O-N 3.15Å
142	Y	93.9	Very high	93.1	Very high	74 Å²	74	66.3 Å²	66.3	29%	0.29	32%	0.324	S	S	.	.	H	α-helix	trans	-60.2	-48.5	174.3	-73.6	-52	0	0	0	111.5	Q138 A139 L144 F145 Y146 K206	Q138-Y142 HydrophobicContact CG-CD2 4.05Å; Q138-Y142 HydrophobicContact CG-CE2 3.49Å; Q138-Y142 VanDerWaalsContact CG-CE2 3.49Å; Q138-Y142 PolarHBondContact NE2-OH 2.92Å; Q138-Y142 WeakPolarHBondContact O-CD2 3.35Å; Q138-Y142 PolarHBondContact O-N 3.48Å; A139-Y142 PolarHBondContact O-N 3.13Å; Y142-L144 VanDerWaalsContact C-N 3.29Å; Y142-L144 PolarHBondContact O-N 2.97Å; Y142-F145 PolarHBondContact O-N 2.92Å; Y142-Y146 HydrophobicContact CD1-CD2 4.33Å; Y142-Y146 AromaticContact CD1-CE2 3.79Å; Y142-Y146 HydrophobicContact CD1-CE2 3.79Å; Y142-Y146 HydrophobicContact CG-CE2 4.43Å; Y142-Y146 WeakPolarHBondContact O-CB 3.48Å; Y142-Y146 WeakPolarHBondContact O-CD2 3.33Å; Y142-Y146 PolarHBondContact O-N 2.84Å; Y142-K206 HydrophobicContact CD2-CD 3.56Å; Y142-K206 HydrophobicContact CE2-CD 3.56Å
143	L	92.7	Very high	93.5	Very high	4 Å²	4	63.9 Å²	63.9	2%	0.021	32%	0.32	C	S	.	.	H	α-helix	trans	-52.4	-50.7	176.8	179	74.3	0	0	0	111	L120 I127 A139 G140 T147 W203 L219	L120-L143 HydrophobicContact CD2-CG 4.44Å; I127-L143 HydrophobicContact CD1-CD2 3.75Å; A139-L143 PolarHBondContact O-N 3.21Å; G140-L143 PolarHBondContact O-N 3.08Å; L143-T147 WeakPolarHBondContact O-CG2 3.41Å; L143-T147 PolarHBondContact O-N 3.15Å; L143-T147 PolarHBondContact O-OG1 2.81Å; L143-W203 HydrophobicContact CD1-CD2 4.31Å; L143-W203 HydrophobicContact CD1-CE3 3.38Å; L143-W203 HydrophobicContact CD1-CH2 4.25Å; L143-W203 HydrophobicContact CD1-CZ3 3.34Å; L143-L219 HydrophobicContact CD1-CD2 4.49Å
144	L	94	Very high	93.6	Very high	56 Å²	56	61.1 Å²	61.1	29%	0.293	31%	0.307	S	S	.	.	H	α-helix	trans	-65	-48.8	-175.8	-179.8	140.1	0	0	0	112.8	L124 G140 L141 Y142 T147 L148	L124-L144 HydrophobicContact CD1-CB 4.04Å; L124-L144 HydrophobicContact CD1-CD1 3.59Å; L124-L144 HydrophobicContact CD1-CG 4.45Å; G140-L144 WeakPolarHBondContact O-CB 3.49Å; G140-L144 PolarHBondContact O-N 3.4Å; G140-L144 VanDerWaalsContact O-N 3.07Å; L141-L144 PolarHBondContact O-N 3.4Å; Y142-L144 VanDerWaalsContact C-N 3.29Å; Y142-L144 PolarHBondContact O-N 2.97Å; L144-T147 PolarHBondContact O-N 3.19Å; L144-T147 PolarHBondContact O-OG1 3.39Å; L144-L148 HydrophobicContact CD1-CD1 4.14Å; L144-L148 HydrophobicContact CD2-CD1 3.54Å; L144-L148 HydrophobicContact CG-CD1 3.53Å; L144-L148 HydrophobicContact CG-CG 4.27Å; L144-L148 VanDerWaalsContact O-CB 3.28Å; L144-L148 WeakPolarHBondContact O-CB 3.3Å; L144-L148 VanDerWaalsContact O-CG 3.31Å; L144-L148 WeakPolarHBondContact O-CG 3.32Å; L144-L148 PolarHBondContact O-N 3.28Å
145	F	94.4	Very high	93.8	Very high	110 Å²	110	57.7 Å²	57.7	48%	0.482	28%	0.283	S	S	.	.	H	α-helix	trans	-72.2	-39.8	-175.3	-77.6	-63.3	0	0	0	113.1	L141 Y142 T147 L149	L141-F145 HydrophobicContact CB-CD2 4.38Å; L141-F145 HydrophobicContact CB-CE2 4.48Å; L141-F145 HydrophobicContact CD2-CE2 4.11Å; L141-F145 VanDerWaalsContact O-CD2 3.23Å; L141-F145 WeakPolarHBondContact O-CD2 3.43Å; L141-F145 PolarHBondContact O-N 3.15Å; Y142-F145 PolarHBondContact O-N 2.92Å; F145-T147 VanDerWaalsContact C-N 3.26Å; F145-T147 PolarHBondContact O-N 3.11Å; F145-L149 VanDerWaalsContact O-CB 3.32Å; F145-L149 WeakPolarHBondContact O-CB 3.41Å; F145-L149 VanDerWaalsContact O-CG 3.26Å; F145-L149 WeakPolarHBondContact O-CG 3.22Å; F145-L149 PolarHBondContact O-N 2.65Å; F145-L149 VanDerWaalsContact O-N 3.16Å
146	Y	92.7	Very high	93.9	Very high	69 Å²	69	57.9 Å²	57.9	27%	0.271	29%	0.287	S	S	.	.	H	α-helix	trans	-60.1	-41.3	177.1	-86.8	-96.2	0	0	0	110.8	Y142 V200 W203	Y142-Y146 HydrophobicContact CD1-CD2 4.33Å; Y142-Y146 AromaticContact CD1-CE2 3.79Å; Y142-Y146 HydrophobicContact CD1-CE2 3.79Å; Y142-Y146 HydrophobicContact CG-CE2 4.43Å; Y142-Y146 WeakPolarHBondContact O-CB 3.48Å; Y142-Y146 WeakPolarHBondContact O-CD2 3.33Å; Y142-Y146 PolarHBondContact O-N 2.84Å; Y146-V200 HydrophobicContact CD1-CG1 3.57Å; Y146-V200 HydrophobicContact CE1-CG1 3.83Å; Y146-W203 HydrophobicContact CD2-CB 4.13Å; Y146-W203 HydrophobicContact CG-CB 4.21Å; Y146-W203 HydrophobicContact CG-CG 4.47Å
147	T	92.9	Very high	93.9	Very high	4 Å²	4	54.4 Å²	54.4	3%	0.025	28%	0.275	C	S	.	.	H	α-helix	trans	-79.4	-45.6	-178	58.7	0	0	0	0	112.8	L120 L143 L144 F145 V150 S151 K194	L120-T147 HydrophobicContact CD1-CG2 4.46Å; L120-T147 WeakPolarHBondContact CD1-OG1 3.36Å; L120-T147 HydrophobicContact CD2-CG2 4.28Å; L143-T147 WeakPolarHBondContact O-CG2 3.41Å; L143-T147 PolarHBondContact O-N 3.15Å; L143-T147 PolarHBondContact O-OG1 2.81Å; L144-T147 PolarHBondContact O-N 3.19Å; L144-T147 PolarHBondContact O-OG1 3.39Å; F145-T147 VanDerWaalsContact C-N 3.26Å; F145-T147 PolarHBondContact O-N 3.11Å; T147-V150 PolarHBondContact O-N 3.03Å; T147-S151 VanDerWaalsContact O-CB 3.27Å; T147-S151 WeakPolarHBondContact O-CB 3.12Å; T147-S151 PolarHBondContact O-N 3.45Å; T147-S151 PolarHBondContact O-OG 3.47Å; T147-S151 VanDerWaalsContact O-OG 3.09Å; T147-K194 HydrophobicContact CG2-CD 3.81Å; T147-K194 VanDerWaalsContact CG2-CE 3.49Å
148	L	92.9	Very high	94	Very high	65 Å²	65	49.2 Å²	49.2	34%	0.34	25%	0.247	S	C	.	.	H	α-helix	trans	-66.4	-41.5	-176	-74.5	178.5	0	0	0	112.9	E117 L144 V150 S151 L152	E117-L148 WeakPolarHBondContact OE2-CD2 3.12Å; L144-L148 HydrophobicContact CD1-CD1 4.14Å; L144-L148 HydrophobicContact CD2-CD1 3.54Å; L144-L148 HydrophobicContact CG-CD1 3.53Å; L144-L148 HydrophobicContact CG-CG 4.27Å; L144-L148 VanDerWaalsContact O-CB 3.28Å; L144-L148 WeakPolarHBondContact O-CB 3.3Å; L144-L148 VanDerWaalsContact O-CG 3.31Å; L144-L148 WeakPolarHBondContact O-CG 3.32Å; L144-L148 PolarHBondContact O-N 3.28Å; L148-V150 PolarHBondContact O-N 3.01Å; L148-S151 WeakPolarHBondContact CA-OG 3.08Å; L148-S151 PolarHBondContact O-N 3.46Å; L148-S151 PolarHBondContact O-OG 3.12Å; L148-L152 WeakPolarHBondContact O-CG 3.42Å; L148-L152 PolarHBondContact O-N 3.46Å; L148-L152 VanDerWaalsContact O-N 3.13Å
149	L	93	Very high	93.9	Very high	117 Å²	117	49.8 Å²	49.8	61%	0.613	25%	0.249	S	C	*	.	H	α-helix	trans	-63.2	-31	-177.6	-72.1	174.1	0	0	0	112.1	F145 P153	F145-L149 VanDerWaalsContact O-CB 3.32Å; F145-L149 WeakPolarHBondContact O-CB 3.41Å; F145-L149 VanDerWaalsContact O-CG 3.26Å; F145-L149 WeakPolarHBondContact O-CG 3.22Å; F145-L149 PolarHBondContact O-N 2.65Å; F145-L149 VanDerWaalsContact O-N 3.16Å; L149-P153 WeakPolarHBondContact O-CD 3.32Å
150	V	92.1	Very high	93.9	Very high	37 Å²	37	53.8 Å²	53.8	22%	0.224	26%	0.264	C	S	.	.	H	α-helix	trans	-95.5	-25.3	-177.8	-168.7	0	0	0	0	112.2	T147 L148 P153 C189 V193	T147-V150 PolarHBondContact O-N 3.03Å; L148-V150 PolarHBondContact O-N 3.01Å; V150-P153 WeakPolarHBondContact O-CD 3.23Å; V150-C189 HydrophobicContact CG1-CB 3.48Å; V150-C189 VanDerWaalsContact CG1-CB 3.48Å; V150-C189 WeakPolarHBondContact CG1-O 3.46Å; V150-V193 HydrophobicContact CB-CG2 3.93Å; V150-V193 HydrophobicContact CG1-CG2 3.94Å; V150-V193 HydrophobicContact CG2-CG2 3.76Å
151	S	93.2	Very high	93.8	Very high	1 Å²	1	53.8 Å²	53.8	1%	0.007	26%	0.263	C	S	.	.	H	α-helix	trans	-74.6	-30.8	174.6	68.4	0	0	0	0	113.4	Y113 E117 T147 L148 M154 L155	Y113-S151 VanDerWaalsContact CE2-O 3.31Å; Y113-S151 WeakPolarHBondContact CE2-O 3.21Å; Y113-S151 PolarHBondContact OH-O 3.49Å; E117-S151 WeakPolarHBondContact OE1-CB 3.2Å; E117-S151 PolarHBondContact OE1-OG 3.08Å; E117-S151 PolarHBondContact OE2-OG 2.83Å; E117-S151 VanDerWaalsContact OE2-OG 3.1Å; T147-S151 VanDerWaalsContact O-CB 3.27Å; T147-S151 WeakPolarHBondContact O-CB 3.12Å; T147-S151 PolarHBondContact O-N 3.45Å; T147-S151 PolarHBondContact O-OG 3.47Å; T147-S151 VanDerWaalsContact O-OG 3.09Å; L148-S151 WeakPolarHBondContact CA-OG 3.08Å; L148-S151 PolarHBondContact O-N 3.46Å; L148-S151 PolarHBondContact O-OG 3.12Å; S151-M154 WeakPolarHBondContact O-CA 3.37Å; S151-M154 VanDerWaalsContact O-CB 3.23Å; S151-M154 WeakPolarHBondContact O-CB 3.23Å; S151-M154 PolarHBondContact O-N 3.27Å; S151-L155 PolarHBondContact O-N 2.86Å; S151-L155 VanDerWaalsContact O-N 3.15Å
152	L	93.3	Very high	93.7	Very high	95 Å²	95	52.9 Å²	52.9	50%	0.497	26%	0.258	S	S	.	.	H	α-helix	trans	-59.4	-44.6	176	-72.5	171.5	0	0	0	113.7	L148 M154 L155 I156	L148-L152 WeakPolarHBondContact O-CG 3.42Å; L148-L152 PolarHBondContact O-N 3.46Å; L148-L152 VanDerWaalsContact O-N 3.13Å; L152-M154 VanDerWaalsContact C-N 3.26Å; L152-M154 PolarHBondContact O-N 3.41Å; L152-L155 WeakPolarHBondContact O-CB 3.36Å; L152-L155 PolarHBondContact O-N 3.03Å; L152-I156 PolarHBondContact O-N 3.47Å
153	P	94.9	Very high	93.7	Very high	49 Å²	49	56 Å²	56	32%	0.318	28%	0.279	S	S	.	.	H	α-helix	trans	-56.1	-36.3	169.3	-28.9	33.6	0	0	0	114.4	L149 V150 I156 G157	L149-P153 WeakPolarHBondContact O-CD 3.32Å; V150-P153 WeakPolarHBondContact O-CD 3.23Å; P153-I156 PolarHBondContact O-N 2.86Å; P153-G157 PolarHBondContact O-N 3.41Å; P153-G157 VanDerWaalsContact O-N 3.12Å
154	M	94.7	Very high	93.5	Very high	0 Å²	0	61.4 Å²	61.4	0%	0	30%	0.303	C	S	.	.	H	α-helix	trans	-59.6	-48.4	175.4	179.7	-172.9	168.6	0	0	109.6	F112 Y113 S151 L152 I156 G157 I158 C186 L187 A190 F191	F112-M154 HydrophobicContact CD1-CE 4.42Å; F112-M154 HydrophobicContact CE1-CE 4.38Å; Y113-M154 HydrophobicContact CD2-CE 4.13Å; Y113-M154 HydrophobicContact CD2-CG 4.28Å; Y113-M154 HydrophobicContact CD2-SD 3.84Å; Y113-M154 HydrophobicContact CE2-CB 4.48Å; Y113-M154 HydrophobicContact CE2-SD 4.4Å; S151-M154 WeakPolarHBondContact O-CA 3.37Å; S151-M154 VanDerWaalsContact O-CB 3.23Å; S151-M154 WeakPolarHBondContact O-CB 3.23Å; S151-M154 PolarHBondContact O-N 3.27Å; L152-M154 VanDerWaalsContact C-N 3.26Å; L152-M154 PolarHBondContact O-N 3.41Å; M154-I156 VanDerWaalsContact C-N 3.28Å; M154-I156 PolarHBondContact O-N 2.61Å; M154-G157 CarbonylContact O-C 3.37Å; M154-G157 WeakPolarHBondContact O-CA 3.41Å; M154-G157 PolarHBondContact O-N 3.45Å; M154-I158 HydrophobicContact CE-CD1 4.16Å; M154-I158 HydrophobicContact CG-CD1 4.27Å; M154-I158 HydrophobicContact CG-CG1 4.4Å; M154-I158 VanDerWaalsContact O-CG1 3.31Å; M154-I158 WeakPolarHBondContact O-CG1 3.41Å; M154-I158 PolarHBondContact O-N 3.41Å; M154-C186 VanDerWaalsContact CA-O 3.25Å; M154-C186 WeakPolarHBondContact CA-O 3.37Å; M154-C186 WeakPolarHBondContact CB-O 3.38Å; M154-C186 PolarHBondContact N-O 3.04Å; M154-L187 HydrophobicContact CG-CD2 4.08Å; M154-A190 HydrophobicContact CB-CB 3.98Å; M154-A190 HydrophobicContact CG-CB 4.43Å; M154-A190 HydrophobicContact SD-CB 3.79Å; M154-F191 HydrophobicContact CE-CE1 4.07Å; M154-F191 HydrophobicContact CE-CE2 4.18Å; M154-F191 HydrophobicContact CE-CZ 3.42Å; M154-F191 VanDerWaalsContact CE-CZ 3.42Å; M154-F191 HydrophobicContact SD-CE1 4.26Å; M154-F191 HydrophobicContact SD-CE2 4.46Å; M154-F191 HydrophobicContact SD-CZ 3.94Å
155	L	95.4	Very high	93.3	Very high	39 Å²	39	60.2 Å²	60.2	20%	0.204	30%	0.296	C	S	.	.	H	α-helix	trans	-53	-42.5	177.4	-176.7	72.1	0	0	0	112.9	F110 Y113 S151 L152 G157 I158 F159	F110-L155 HydrophobicContact CD2-CD1 4.41Å; F110-L155 HydrophobicContact CE2-CD1 4.06Å; Y113-L155 HydrophobicContact CD1-CD1 3.82Å; Y113-L155 HydrophobicContact CE1-CB 4.1Å; Y113-L155 HydrophobicContact CE1-CD1 3.6Å; Y113-L155 HydrophobicContact CE1-CG 4.26Å; Y113-L155 HydrophobicContact CE2-CB 4.24Å; S151-L155 PolarHBondContact O-N 2.86Å; S151-L155 VanDerWaalsContact O-N 3.15Å; L152-L155 WeakPolarHBondContact O-CB 3.36Å; L152-L155 PolarHBondContact O-N 3.03Å; L155-G157 VanDerWaalsContact C-N 3.33Å; L155-G157 PolarHBondContact O-N 3.04Å; L155-I158 WeakPolarHBondContact O-CB 3.11Å; L155-I158 PolarHBondContact O-N 3.28Å; L155-F159 HydrophobicContact CD1-CD2 4.48Å; L155-F159 HydrophobicContact CD1-CE2 3.8Å; L155-F159 HydrophobicContact CD1-CZ 3.95Å; L155-F159 HydrophobicContact CD2-CE2 3.98Å; L155-F159 HydrophobicContact CG-CD2 4.13Å; L155-F159 HydrophobicContact CG-CE2 3.65Å; L155-F159 HydrophobicContact CG-CZ 4.31Å; L155-F159 WeakPolarHBondContact O-CD2 3.27Å; L155-F159 PolarHBondContact O-N 3.21Å
156	I	95.2	Very high	93	Very high	118 Å²	118	57.5 Å²	57.5	61%	0.605	30%	0.299	S	S	*	.	H	α-helix	trans	-62.1	-43.8	176.3	-60.1	170.7	0	0	0	110.4	L152 P153 M154 I158 F159 Y160	L152-I156 PolarHBondContact O-N 3.47Å; P153-I156 PolarHBondContact O-N 2.86Å; M154-I156 VanDerWaalsContact C-N 3.28Å; M154-I156 PolarHBondContact O-N 2.61Å; I156-I158 VanDerWaalsContact C-N 3.31Å; I156-I158 PolarHBondContact O-N 3.09Å; I156-F159 PolarHBondContact O-N 3.31Å; I156-Y160 PolarHBondContact O-N 3.21Å
157	G	94.6	Very high	92.9	Very high	4 Å²	4	55.4 Å²	55.4	4%	0.041	29%	0.294	C	S	.	.	H	α-helix	trans	-59.7	-38.7	174	0	0	0	0	0	113.1	P153 M154 L155 Y160 L161	P153-G157 PolarHBondContact O-N 3.41Å; P153-G157 VanDerWaalsContact O-N 3.12Å; M154-G157 CarbonylContact O-C 3.37Å; M154-G157 WeakPolarHBondContact O-CA 3.41Å; M154-G157 PolarHBondContact O-N 3.45Å; L155-G157 VanDerWaalsContact C-N 3.33Å; L155-G157 PolarHBondContact O-N 3.04Å; G157-Y160 PolarHBondContact O-N 3.33Å; G157-L161 WeakPolarHBondContact O-CG 3.18Å; G157-L161 PolarHBondContact O-N 3.42Å
158	I	94.9	Very high	92.8	Very high	0 Å²	0	56.4 Å²	56.4	0%	0	30%	0.299	C	S	.	.	H	α-helix	trans	-62.1	-51.4	175.5	-56.1	177.6	0	0	0	110.2	L109 F110 Y113 M154 L155 I156 Y160 L161 M162 M168 L187	L109-I158 HydrophobicContact CD2-CB 4.09Å; L109-I158 HydrophobicContact CD2-CD1 3.5Å; L109-I158 HydrophobicContact CD2-CG1 3.3Å; L109-I158 HydrophobicContact CD2-CG2 3.82Å; F110-I158 HydrophobicContact CB-CG2 4.19Å; F110-I158 HydrophobicContact CD2-CG2 4.38Å; Y113-I158 HydrophobicContact CD1-CD1 4.47Å; Y113-I158 HydrophobicContact CD2-CD1 4Å; Y113-I158 HydrophobicContact CG-CD1 3.74Å; M154-I158 HydrophobicContact CE-CD1 4.16Å; M154-I158 HydrophobicContact CG-CD1 4.27Å; M154-I158 HydrophobicContact CG-CG1 4.4Å; M154-I158 VanDerWaalsContact O-CG1 3.31Å; M154-I158 WeakPolarHBondContact O-CG1 3.41Å; M154-I158 PolarHBondContact O-N 3.41Å; L155-I158 WeakPolarHBondContact O-CB 3.11Å; L155-I158 PolarHBondContact O-N 3.28Å; I156-I158 VanDerWaalsContact C-N 3.31Å; I156-I158 PolarHBondContact O-N 3.09Å; I158-Y160 VanDerWaalsContact C-N 3.26Å; I158-Y160 PolarHBondContact O-N 3.35Å; I158-L161 WeakPolarHBondContact O-CB 3.49Å; I158-L161 PolarHBondContact O-N 3.47Å; I158-L161 VanDerWaalsContact O-N 3.09Å; I158-M162 PolarHBondContact O-N 3.49Å; I158-M168 HydrophobicContact CG2-CE 3.59Å; I158-M168 HydrophobicContact CG2-SD 3.66Å; I158-M168 WeakPolarHBondContact O-CE 3.3Å; I158-L187 HydrophobicContact CG1-CD2 4.28Å
159	F	94.8	Very high	92.8	Very high	104 Å²	104	56.8 Å²	56.8	46%	0.456	30%	0.302	S	S	.	.	H	α-helix	trans	-62.5	-34.4	179.5	-68.7	-46.5	0	0	0	112.9	F110 L155 I156 M162 N163	F110-F159 HydrophobicContact CD2-CE1 4.25Å; F110-F159 AromaticContact CE2-CE1 3.93Å; F110-F159 HydrophobicContact CE2-CE1 3.93Å; F110-F159 AromaticContact CE2-CZ 3.95Å; F110-F159 HydrophobicContact CE2-CZ 3.95Å; L155-F159 HydrophobicContact CD1-CD2 4.48Å; L155-F159 HydrophobicContact CD1-CE2 3.8Å; L155-F159 HydrophobicContact CD1-CZ 3.95Å; L155-F159 HydrophobicContact CD2-CE2 3.98Å; L155-F159 HydrophobicContact CG-CD2 4.13Å; L155-F159 HydrophobicContact CG-CE2 3.65Å; L155-F159 HydrophobicContact CG-CZ 4.31Å; L155-F159 WeakPolarHBondContact O-CD2 3.27Å; L155-F159 PolarHBondContact O-N 3.21Å; I156-F159 PolarHBondContact O-N 3.31Å; F159-M162 WeakPolarHBondContact O-CB 3.46Å; F159-M162 PolarHBondContact O-N 3.06Å; F159-N163 PolarHBondContact O-N 3.43Å
160	Y	93.9	Very high	92.6	Very high	86 Å²	86	51.3 Å²	51.3	34%	0.337	27%	0.273	S	S	.	.	H	α-helix	trans	-62.7	-44.4	172.5	-178.7	-88.2	0	0	0	112.4	I156 G157 I158 M162 N163 K164 Y180 L183	I156-Y160 PolarHBondContact O-N 3.21Å; G157-Y160 PolarHBondContact O-N 3.33Å; I158-Y160 VanDerWaalsContact C-N 3.26Å; I158-Y160 PolarHBondContact O-N 3.35Å; Y160-M162 VanDerWaalsContact C-N 3.27Å; Y160-M162 PolarHBondContact O-N 3.44Å; Y160-N163 PolarHBondContact O-N 3.4Å; Y160-K164 HydrophobicContact CD1-CG 4.22Å; Y160-K164 HydrophobicContact CE1-CG 3.77Å; Y160-K164 VanDerWaalsContact CZ-CE 3.48Å; Y160-K164 PolarHBondContact O-N 2.8Å; Y160-K164 WeakPolarHBondContact OH-CE 3.26Å; Y160-Y180 HydrophobicContact CE1-CD2 4.21Å; Y160-Y180 HydrophobicContact CE1-CE2 4.33Å; Y160-L183 HydrophobicContact CD1-CD1 3.42Å; Y160-L183 VanDerWaalsContact CD1-CD1 3.42Å; Y160-L183 HydrophobicContact CE1-CD1 3.73Å
161	L	92.6	Very high	92.3	Very high	0 Å²	0	53.5 Å²	53.5	0%	0	28%	0.278	C	S	.	.	H	α-helix	trans	-59.5	-39	174.4	-74	174.2	0	0	0	111.6	G157 I158 N163 K164 I165 M168 M173 F178 L183 L187 F237	G157-L161 WeakPolarHBondContact O-CG 3.18Å; G157-L161 PolarHBondContact O-N 3.42Å; I158-L161 WeakPolarHBondContact O-CB 3.49Å; I158-L161 PolarHBondContact O-N 3.47Å; I158-L161 VanDerWaalsContact O-N 3.09Å; L161-N163 VanDerWaalsContact C-N 3.3Å; L161-N163 PolarHBondContact O-N 3.39Å; L161-K164 PolarHBondContact O-N 3.16Å; L161-I165 HydrophobicContact CB-CD1 4.25Å; L161-I165 HydrophobicContact CD2-CD1 3.96Å; L161-I165 PolarHBondContact O-N 3.48Å; L161-I165 VanDerWaalsContact O-N 3.07Å; L161-M168 HydrophobicContact CB-CE 4.17Å; L161-M173 HydrophobicContact CB-CE 4.22Å; L161-M173 HydrophobicContact CD1-CE 3.8Å; L161-M173 HydrophobicContact CD2-CE 3.99Å; L161-M173 HydrophobicContact CG-CE 4.23Å; L161-F178 HydrophobicContact CD2-CD1 4.21Å; L161-F178 HydrophobicContact CD2-CD2 4.14Å; L161-F178 HydrophobicContact CD2-CE1 4.09Å; L161-F178 HydrophobicContact CD2-CE2 4.01Å; L161-F178 HydrophobicContact CD2-CG 4.28Å; L161-F178 HydrophobicContact CD2-CZ 4.06Å; L161-L183 HydrophobicContact CD2-CD1 3.64Å; L161-L183 HydrophobicContact CD2-CD2 4.24Å; L161-L183 HydrophobicContact CD2-CG 4.48Å; L161-L183 HydrophobicContact CG-CD1 3.99Å; L161-L187 HydrophobicContact CD1-CD1 3.66Å; L161-L187 HydrophobicContact CD1-CD2 4.43Å; L161-F237 HydrophobicContact CD1-CE2 4Å; L161-F237 HydrophobicContact CD1-CZ 4.26Å
162	M	92.9	Very high	92.1	Very high	78 Å²	78	57.5 Å²	57.5	38%	0.384	30%	0.299	S	S	.	.	H	α-helix	trans	-57.2	-47.7	177.8	-170.9	44	-169.8	0	0	111.2	I158 F159 Y160 K164 G166 M168	I158-M162 PolarHBondContact O-N 3.49Å; F159-M162 WeakPolarHBondContact O-CB 3.46Å; F159-M162 PolarHBondContact O-N 3.06Å; Y160-M162 VanDerWaalsContact C-N 3.27Å; Y160-M162 PolarHBondContact O-N 3.44Å; M162-K164 PolarHBondContact O-N 3.05Å; M162-G166 WeakPolarHBondContact CE-O 3.34Å; M162-G166 WeakPolarHBondContact O-CA 3.16Å; M162-G166 PolarHBondContact O-N 3.49Å; M162-M168 HydrophobicContact CB-CE 3.3Å; M162-M168 HydrophobicContact CG-CE 4.14Å; M162-M168 HydrophobicContact SD-CE 4.2Å; M162-M168 HydrophobicContact SD-CG 4.02Å
163	N	92.4	Very high	91.9	Very high	140 Å²	140	53 Å²	53	75%	0.749	28%	0.275	S	S	*	.	H	α-helix	trans	-67.1	-26.9	-176.9	-66.8	-12.4	0	0	0	112.5	F159 Y160 L161	F159-N163 PolarHBondContact O-N 3.43Å; Y160-N163 PolarHBondContact O-N 3.4Å; L161-N163 VanDerWaalsContact C-N 3.3Å; L161-N163 PolarHBondContact O-N 3.39Å
164	K	89.8	Confident	91.4	Very high	118 Å²	118	53.9 Å²	53.9	51%	0.513	28%	0.277	S	S	.	.	H	α-helix	trans	-84.7	-37.6	-178.9	-70.8	-63.8	-174.6	-178.7	0	113.8	Y160 L161 M162	Y160-K164 HydrophobicContact CD1-CG 4.22Å; Y160-K164 HydrophobicContact CE1-CG 3.77Å; Y160-K164 VanDerWaalsContact CZ-CE 3.48Å; Y160-K164 PolarHBondContact O-N 2.8Å; Y160-K164 WeakPolarHBondContact OH-CE 3.26Å; L161-K164 PolarHBondContact O-N 3.16Å; M162-K164 PolarHBondContact O-N 3.05Å
165	I	89.6	Confident	90.9	Very high	31 Å²	31	60.2 Å²	60.2	16%	0.159	31%	0.311	C	S	.	.	H	α-helix	trans	-108.7	-26.8	-168.1	-57.4	153	0	0	0	111.3	L161 S167 M173 F176 F178	L161-I165 HydrophobicContact CB-CD1 4.25Å; L161-I165 HydrophobicContact CD2-CD1 3.96Å; L161-I165 PolarHBondContact O-N 3.48Å; L161-I165 VanDerWaalsContact O-N 3.07Å; I165-S167 PolarHBondContact O-N 3.26Å; I165-M173 HydrophobicContact CB-SD 4.32Å; I165-M173 HydrophobicContact CD1-CE 3.17Å; I165-M173 HydrophobicContact CD1-SD 3.19Å; I165-M173 WeakPolarHBondContact CD1-SD 3.24Å; I165-M173 HydrophobicContact CG1-SD 4.3Å; I165-M173 HydrophobicContact CG2-SD 4.01Å; I165-F176 HydrophobicContact CG1-CD2 4.49Å; I165-F176 HydrophobicContact CG2-CD2 3.82Å; I165-F176 HydrophobicContact CG2-CE2 3.44Å; I165-F176 VanDerWaalsContact CG2-CE2 3.44Å; I165-F176 HydrophobicContact CG2-CZ 3.98Å; I165-F178 HydrophobicContact CD1-CE1 3.76Å; I165-F178 HydrophobicContact CD1-CE2 3.8Å; I165-F178 HydrophobicContact CD1-CZ 3.06Å; I165-F178 HydrophobicContact CG1-CE1 3.95Å; I165-F178 HydrophobicContact CG1-CZ 3.54Å
166	G	88.5	Confident	90.5	Very high	52 Å²	52	62.8 Å²	62.8	54%	0.536	32%	0.32	S	S	.	.	S	Bend	trans	74.9	-0.7	-174.4	0	0	0	0	0	114.5	M162	M162-G166 WeakPolarHBondContact CE-O 3.34Å; M162-G166 WeakPolarHBondContact O-CA 3.16Å; M162-G166 PolarHBondContact O-N 3.49Å
167	S	89.8	Confident	90	Very high	25 Å²	25	61.9 Å²	61.9	18%	0.175	32%	0.315	C	S	.	.			trans	-138.8	152.4	176.7	79.7	0	0	0	0	112	I165 M173	I165-S167 PolarHBondContact O-N 3.26Å; S167-M173 VanDerWaalsContact O-SD 3.38Å
168	M	90.6	Very high	89.6	Confident	25 Å²	25	62.4 Å²	62.4	12%	0.123	32%	0.316	C	S	.	.			trans	-112.4	0.9	-178.4	-82	-67.3	159	0	0	114.1	S108 L109 F110 I158 L161 M162	S108-M168 CarbonylContact C-O 3.59Å; S108-M168 VanDerWaalsContact CA-O 3.29Å; S108-M168 WeakPolarHBondContact CA-O 3.45Å; L109-M168 HydrophobicContact CB-SD 4.19Å; L109-M168 PolarHBondContact N-O 2.96Å; F110-M168 HydrophobicContact CB-CG 4.48Å; I158-M168 HydrophobicContact CG2-CE 3.59Å; I158-M168 HydrophobicContact CG2-SD 3.66Å; I158-M168 WeakPolarHBondContact O-CE 3.3Å; L161-M168 HydrophobicContact CB-CE 4.17Å; M162-M168 HydrophobicContact CB-CE 3.3Å; M162-M168 HydrophobicContact CG-CE 4.14Å; M162-M168 HydrophobicContact SD-CE 4.2Å; M162-M168 HydrophobicContact SD-CG 4.02Å
169	N	92.6	Very high	89.2	Confident	73 Å²	73	66.9 Å²	66.9	39%	0.39	34%	0.34	S	S	.	.	B	Isolated β-bridge	trans	-78.5	126.4	-173.6	-69.1	-16.5	0	0	0	110.4	M107 Y171 L172 M173	M107-N169 CarbonylContact O-C 3.59Å; M107-N169 WeakPolarHBondContact O-CA 3.39Å; N169-Y171 PolarHBondContact O-N 2.67Å; N169-L172 HydrophobicContact CB-CD1 4.4Å; N169-L172 PolarHBondContact O-N 2.93Å; N169-M173 VanDerWaalsContact O-CG 3.23Å; N169-M173 WeakPolarHBondContact O-CG 3.34Å; N169-M173 PolarHBondContact O-N 2.81Å
170	F	89.6	Confident	89	Confident	2 Å²	2	66.9 Å²	66.9	1%	0.009	34%	0.338	C	S	.	.	H	α-helix	trans	-49	-41.1	-178.8	-73.2	-61.3	0	0	0	112.7	W45 S106 M107 L109 F112 L172 M173 N174 R233	W45-F170 HydrophobicContact CH2-CD2 4.15Å; W45-F170 HydrophobicContact CZ2-CB 4.28Å; W45-F170 HydrophobicContact CZ2-CD2 4.1Å; S106-F170 WeakPolarHBondContact O-CE2 3.12Å; M107-F170 VanDerWaalsContact C-CD2 3.49Å; M107-F170 WeakPolarHBondContact O-CD2 3.34Å; M107-F170 PolarHBondContact O-N 3.21Å; L109-F170 HydrophobicContact CB-CE1 3.96Å; L109-F170 HydrophobicContact CB-CZ 4.11Å; L109-F170 HydrophobicContact CD1-CD1 4.46Å; L109-F170 HydrophobicContact CD1-CE1 3.8Å; L109-F170 HydrophobicContact CG-CE1 3.92Å; L109-F170 HydrophobicContact CG-CZ 4.22Å; F112-F170 HydrophobicContact CB-CE2 4.26Å; F112-F170 HydrophobicContact CB-CZ 4.09Å; F112-F170 HydrophobicContact CD1-CZ 4.37Å; F112-F170 HydrophobicContact CG-CZ 4.21Å; F170-L172 PolarHBondContact O-N 3.44Å; F170-M173 PolarHBondContact O-N 3.22Å; F170-N174 PolarHBondContact O-N 3.16Å; F170-N174 PolarHBondContact O-OD1 2.92Å; F170-R233 HydrophobicContact CD1-CB 3.99Å; F170-R233 HydrophobicContact CE1-CB 3.6Å; F170-R233 HydrophobicContact CE1-CG 4.33Å; F170-R233 HydrophobicContact CZ-CB 3.97Å; F170-R233 HydrophobicContact CZ-CG 4.31Å
171	Y	86.1	Confident	88.9	Confident	84 Å²	84	66.3 Å²	66.3	33%	0.329	34%	0.34	S	S	.	.	H	α-helix	trans	-57.1	-46.7	176.9	-80.6	-69.1	0	0	0	115.2	W45 M107 N169	W45-Y171 WeakPolarHBondContact CA-OH 3.49Å; W45-Y171 HydrophobicContact CB-CE2 3.69Å; W45-Y171 WeakPolarHBondContact CB-OH 3.44Å; W45-Y171 AromaticContact CD1-CE1 3.3Å; W45-Y171 AromaticContact CD1-CE2 3.18Å; W45-Y171 AromaticContact CD1-CZ 2.8Å; W45-Y171 AromaticContact CD2-CE2 3.9Å; W45-Y171 HydrophobicContact CD2-CE2 3.9Å; W45-Y171 AromaticContact CE2-CE2 3.96Å; W45-Y171 HydrophobicContact CG-CD2 4.36Å; W45-Y171 HydrophobicContact CG-CE1 4.15Å; W45-Y171 AromaticContact CG-CE2 3.27Å; W45-Y171 HydrophobicContact CG-CE2 3.27Å; W45-Y171 AromaticContact CG-CZ 3.22Å; W45-Y171 PolarHBondContact N-OH 3.32Å; W45-Y171 AromaticContact NE1-CD2 3.95Å; W45-Y171 AromaticContact NE1-CE1 3.72Å; W45-Y171 AromaticContact NE1-CE2 3.49Å; W45-Y171 AromaticContact NE1-CZ 3.47Å; M107-Y171 HydrophobicContact CE-CD2 4.48Å; M107-Y171 HydrophobicContact CE-CE2 3.72Å; M107-Y171 HydrophobicContact SD-CD2 3.78Å; M107-Y171 HydrophobicContact SD-CE2 3.54Å; M107-Y171 VanDerWaalsContact SD-CE2 3.54Å; N169-Y171 PolarHBondContact O-N 2.67Å
172	L	87.8	Confident	88.9	Confident	85 Å²	85	72.7 Å²	72.7	45%	0.445	37%	0.374	S	S	.	.	H	α-helix	trans	-75.3	-35.6	-179.1	-65.8	174.2	0	0	0	110.2	N169 F170 N174 N175 F176	N169-L172 HydrophobicContact CB-CD1 4.4Å; N169-L172 PolarHBondContact O-N 2.93Å; F170-L172 PolarHBondContact O-N 3.44Å; L172-N174 VanDerWaalsContact C-N 3.3Å; L172-N174 PolarHBondContact O-N 3.09Å; L172-N175 PolarHBondContact O-N 3.12Å; L172-F176 VanDerWaalsContact O-CD2 3.31Å; L172-F176 WeakPolarHBondContact O-CD2 3.35Å; L172-F176 WeakPolarHBondContact O-CE2 3.22Å
173	M	88.3	Confident	88.9	Confident	0 Å²	0	69.3 Å²	69.3	0%	0	36%	0.357	C	S	.	.	H	α-helix	trans	-61	-37	178.2	-65.4	-67.2	-64.5	0	0	112.6	L161 I165 S167 N169 F170 N175 F176 F178 F237	L161-M173 HydrophobicContact CB-CE 4.22Å; L161-M173 HydrophobicContact CD1-CE 3.8Å; L161-M173 HydrophobicContact CD2-CE 3.99Å; L161-M173 HydrophobicContact CG-CE 4.23Å; I165-M173 HydrophobicContact CB-SD 4.32Å; I165-M173 HydrophobicContact CD1-CE 3.17Å; I165-M173 HydrophobicContact CD1-SD 3.19Å; I165-M173 WeakPolarHBondContact CD1-SD 3.24Å; I165-M173 HydrophobicContact CG1-SD 4.3Å; I165-M173 HydrophobicContact CG2-SD 4.01Å; S167-M173 VanDerWaalsContact O-SD 3.38Å; N169-M173 VanDerWaalsContact O-CG 3.23Å; N169-M173 WeakPolarHBondContact O-CG 3.34Å; N169-M173 PolarHBondContact O-N 2.81Å; F170-M173 PolarHBondContact O-N 3.22Å; M173-N175 PolarHBondContact O-N 3.4Å; M173-N175 VanDerWaalsContact O-N 3.09Å; M173-F176 PolarHBondContact O-N 3.12Å; M173-F178 HydrophobicContact CE-CE2 4.09Å; M173-F178 HydrophobicContact CE-CZ 4.46Å; M173-F237 HydrophobicContact CB-CD1 4.1Å; M173-F237 HydrophobicContact CB-CG 4.44Å; M173-F237 HydrophobicContact CE-CD2 4.43Å; M173-F237 HydrophobicContact CE-CE2 4.47Å; M173-F237 WeakPolarHBondContact O-CB 3.19Å
174	N	85.9	Confident	88.9	Confident	67 Å²	67	62.7 Å²	62.7	36%	0.358	32%	0.322	S	S	.	.	T	Hydrogen-bonded Turn	trans	-59.4	-21.7	-179.2	-73.9	-6.8	0	0	0	114	F170 L172 F176 S236	F170-N174 PolarHBondContact O-N 3.16Å; F170-N174 PolarHBondContact O-OD1 2.92Å; L172-N174 VanDerWaalsContact C-N 3.3Å; L172-N174 PolarHBondContact O-N 3.09Å; N174-F176 VanDerWaalsContact C-N 3.29Å; N174-S236 WeakPolarHBondContact OD1-CB 2.85Å; N174-S236 PolarHBondContact OD1-OG 2.79Å
175	N	84.6	Confident	89.1	Confident	133 Å²	133	60.8 Å²	60.8	71%	0.711	31%	0.314	S	S	*	.	T	Hydrogen-bonded Turn	trans	-79.9	-12.3	178.3	-65.3	-13.8	0	0	0	112.9	L172 M173	L172-N175 PolarHBondContact O-N 3.12Å; M173-N175 PolarHBondContact O-N 3.4Å; M173-N175 VanDerWaalsContact O-N 3.09Å
176	F	85.6	Confident	89.3	Confident	93 Å²	93	60.4 Å²	60.4	41%	0.408	31%	0.314	S	S	.	.			trans	-101.9	139.9	-178.8	-62.7	-80.2	0	0	0	111.3	I165 L172 M173 N174 F178	I165-F176 HydrophobicContact CG1-CD2 4.49Å; I165-F176 HydrophobicContact CG2-CD2 3.82Å; I165-F176 HydrophobicContact CG2-CE2 3.44Å; I165-F176 VanDerWaalsContact CG2-CE2 3.44Å; I165-F176 HydrophobicContact CG2-CZ 3.98Å; L172-F176 VanDerWaalsContact O-CD2 3.31Å; L172-F176 WeakPolarHBondContact O-CD2 3.35Å; L172-F176 WeakPolarHBondContact O-CE2 3.22Å; M173-F176 PolarHBondContact O-N 3.12Å; N174-F176 VanDerWaalsContact C-N 3.29Å; F176-F178 HydrophobicContact CB-CE1 4.37Å; F176-F178 HydrophobicContact CB-CE2 3.62Å; F176-F178 HydrophobicContact CB-CZ 3.44Å; F176-F178 VanDerWaalsContact CB-CZ 3.44Å; F176-F178 HydrophobicContact CG-CZ 4.15Å
177	M	86	Confident	89.6	Confident	99 Å²	99	57.9 Å²	57.9	49%	0.488	29%	0.288	S	S	.	.			trans	-110.9	109.1	174.8	-71.7	-70.4	-160.7	0	0	109.6	Q239 L240	M177-Q239 HydrophobicContact CE-CB 4.33Å; M177-Q239 HydrophobicContact CE-CG 4.49Å; M177-Q239 HydrophobicContact SD-CB 4.13Å; M177-Q239 HydrophobicContact SD-CG 4.47Å; M177-L240 HydrophobicContact CB-CD1 3.78Å; M177-L240 HydrophobicContact CB-CG 4.45Å; M177-L240 HydrophobicContact CG-CD1 4.38Å; M177-L240 HydrophobicContact SD-CD1 4.48Å; M177-L240 HydrophobicContact SD-CG 4.18Å
178	F	85.4	Confident	89.8	Confident	15 Å²	15	56.8 Å²	56.8	7%	0.066	28%	0.28	C	S	.	.			trans	-89.7	136.3	-179.9	-62.4	-74.5	0	0	0	112.2	L161 I165 M173 F176 Y180 F237 L238 M241	L161-F178 HydrophobicContact CD2-CD1 4.21Å; L161-F178 HydrophobicContact CD2-CD2 4.14Å; L161-F178 HydrophobicContact CD2-CE1 4.09Å; L161-F178 HydrophobicContact CD2-CE2 4.01Å; L161-F178 HydrophobicContact CD2-CG 4.28Å; L161-F178 HydrophobicContact CD2-CZ 4.06Å; I165-F178 HydrophobicContact CD1-CE1 3.76Å; I165-F178 HydrophobicContact CD1-CE2 3.8Å; I165-F178 HydrophobicContact CD1-CZ 3.06Å; I165-F178 HydrophobicContact CG1-CE1 3.95Å; I165-F178 HydrophobicContact CG1-CZ 3.54Å; M173-F178 HydrophobicContact CE-CE2 4.09Å; M173-F178 HydrophobicContact CE-CZ 4.46Å; F176-F178 HydrophobicContact CB-CE1 4.37Å; F176-F178 HydrophobicContact CB-CE2 3.62Å; F176-F178 HydrophobicContact CB-CZ 3.44Å; F176-F178 VanDerWaalsContact CB-CZ 3.44Å; F176-F178 HydrophobicContact CG-CZ 4.15Å; F178-Y180 HydrophobicContact CD1-CD2 4.39Å; F178-Y180 HydrophobicContact CD1-CE2 4.39Å; F178-F237 HydrophobicContact CD2-CB 4.48Å; F178-F237 AromaticContact CD2-CD2 3.91Å; F178-F237 HydrophobicContact CD2-CD2 3.91Å; F178-F237 HydrophobicContact CE2-CB 4.42Å; F178-F237 HydrophobicContact CE2-CD2 4.17Å; F178-L238 HydrophobicContact CB-CD2 4.26Å; F178-M241 VanDerWaalsContact O-CG 3.28Å; F178-M241 WeakPolarHBondContact O-CG 3.43Å
179	N	87	Confident	89.9	Confident	94 Å²	94	57.4 Å²	57.4	50%	0.503	29%	0.286	S	S	.	.			trans	-112.9	24.8	-179.2	-80.6	-18.1	0	0	0	114.1	L240 M241	N179-L240 WeakPolarHBondContact OD1-CB 3.3Å; N179-L240 WeakPolarHBondContact OD1-CD1 3.4Å; N179-M241 VanDerWaalsContact CA-SD 3.57Å
180	Y	89.9	Confident	90	Very high	105 Å²	105	54.1 Å²	54.1	41%	0.412	27%	0.269	S	S	.	.			trans	-101.6	117.9	-174.9	-58.3	-70	0	0	0	112.2	Y160 F178 L183 Y184	Y160-Y180 HydrophobicContact CE1-CD2 4.21Å; Y160-Y180 HydrophobicContact CE1-CE2 4.33Å; F178-Y180 HydrophobicContact CD1-CD2 4.39Å; F178-Y180 HydrophobicContact CD1-CE2 4.39Å; Y180-L183 PolarHBondContact O-N 2.8Å; Y180-Y184 PolarHBondContact O-N 3.11Å
181	D	92	Very high	90.2	Very high	73 Å²	73	54 Å²	54	39%	0.39	27%	0.269	S	S	.	.	H	α-helix	trans	-61.5	-48.1	-177.6	-66.2	-58.1	0	0	0	112.7	L183 Y184 F185 M241 Y245	D181-L183 VanDerWaalsContact C-N 3.27Å; D181-L183 PolarHBondContact O-N 2.87Å; D181-Y184 WeakPolarHBondContact O-CB 3.04Å; D181-Y184 PolarHBondContact O-N 3.24Å; D181-Y184 VanDerWaalsContact O-N 3.17Å; D181-F185 VanDerWaalsContact O-CD2 3.24Å; D181-F185 WeakPolarHBondContact O-CD2 3.33Å; D181-F185 PolarHBondContact O-N 3.42Å; D181-M241 HydrophobicContact CB-CE 4Å; D181-M241 WeakPolarHBondContact OD1-CE 3.37Å; D181-Y245 VanDerWaalsContact OD1-CE2 3.27Å; D181-Y245 WeakPolarHBondContact OD1-CE2 3.39Å; D181-Y245 PolarHBondContact OD1-OH 3.43Å
182	L	92.5	Very high	90.6	Very high	135 Å²	135	50.3 Å²	50.3	71%	0.707	26%	0.255	S	S	*	.	H	α-helix	trans	-62.4	-37.6	-178.2	-174	144.2	0	0	0	111.9	Y184 F185 C186	L182-Y184 VanDerWaalsContact C-N 3.33Å; L182-Y184 PolarHBondContact O-N 2.88Å; L182-F185 PolarHBondContact O-N 3.34Å; L182-C186 PolarHBondContact O-N 2.63Å; L182-C186 PolarHBondContact O-SG 2.92Å
183	L	92.5	Very high	90.9	Very high	7 Å²	7	46.6 Å²	46.6	4%	0.037	24%	0.235	C	C	.	.	H	α-helix	trans	-64.7	-39.1	178.1	-173.7	145.1	0	0	0	111.8	Y160 L161 Y180 D181 C186 L187 L238	Y160-L183 HydrophobicContact CD1-CD1 3.42Å; Y160-L183 VanDerWaalsContact CD1-CD1 3.42Å; Y160-L183 HydrophobicContact CE1-CD1 3.73Å; L161-L183 HydrophobicContact CD2-CD1 3.64Å; L161-L183 HydrophobicContact CD2-CD2 4.24Å; L161-L183 HydrophobicContact CD2-CG 4.48Å; L161-L183 HydrophobicContact CG-CD1 3.99Å; Y180-L183 PolarHBondContact O-N 2.8Å; D181-L183 VanDerWaalsContact C-N 3.27Å; D181-L183 PolarHBondContact O-N 2.87Å; L183-C186 PolarHBondContact O-N 3.13Å; L183-L187 HydrophobicContact CD2-CD1 3.42Å; L183-L187 VanDerWaalsContact CD2-CD1 3.42Å; L183-L187 HydrophobicContact CD2-CG 4.35Å; L183-L187 HydrophobicContact CG-CD1 3.99Å; L183-L187 WeakPolarHBondContact O-CG 3.15Å; L183-L187 PolarHBondContact O-N 3.05Å; L183-L238 HydrophobicContact CD2-CD2 3.45Å; L183-L238 VanDerWaalsContact CD2-CD2 3.45Å
184	Y	93.8	Very high	91.1	Very high	0 Å²	0	46.8 Å²	46.8	0%	0	24%	0.236	C	C	.	.	H	α-helix	trans	-58.3	-50.1	175.3	172.6	-92.7	0	0	0	111.4	Y180 D181 L182 L187 L188 L238 M241 N242 Y245 W249	Y180-Y184 PolarHBondContact O-N 3.11Å; D181-Y184 WeakPolarHBondContact O-CB 3.04Å; D181-Y184 PolarHBondContact O-N 3.24Å; D181-Y184 VanDerWaalsContact O-N 3.17Å; L182-Y184 VanDerWaalsContact C-N 3.33Å; L182-Y184 PolarHBondContact O-N 2.88Å; Y184-L187 PolarHBondContact O-N 3.08Å; Y184-L188 HydrophobicContact CD1-CD1 4.07Å; Y184-L188 HydrophobicContact CD2-CD1 3.38Å; Y184-L188 HydrophobicContact CD2-CG 4.44Å; Y184-L188 HydrophobicContact CE1-CD1 3.67Å; Y184-L188 HydrophobicContact CE2-CD1 2.93Å; Y184-L188 HydrophobicContact CE2-CG 4.29Å; Y184-L188 HydrophobicContact CG-CD1 3.94Å; Y184-L188 WeakPolarHBondContact O-CB 3.33Å; Y184-L188 PolarHBondContact O-N 3.49Å; Y184-L188 WeakPolarHBondContact OH-CD1 3.5Å; Y184-L238 HydrophobicContact CD2-CD1 4.35Å; Y184-M241 HydrophobicContact CD2-CB 3.43Å; Y184-M241 VanDerWaalsContact CD2-CB 3.43Å; Y184-M241 HydrophobicContact CE2-CB 4.15Å; Y184-M241 HydrophobicContact CG-CB 3.86Å; Y184-N242 VanDerWaalsContact CE2-CA 3.45Å; Y184-N242 HydrophobicContact CE2-CB 3.94Å; Y184-N242 PolarHBondContact OH-OD1 3.37Å; Y184-Y245 AromaticContact CD1-CD2 3.53Å; Y184-Y245 HydrophobicContact CD1-CD2 3.53Å; Y184-Y245 HydrophobicContact CD1-CE2 4.11Å; Y184-Y245 HydrophobicContact CD1-CG 4.18Å; Y184-Y245 AromaticContact CE1-CD2 3.51Å; Y184-Y245 HydrophobicContact CE1-CD2 3.51Å; Y184-Y245 HydrophobicContact CE1-CE2 4.48Å; Y184-Y245 AromaticContact CE1-CG 3.73Å; Y184-Y245 HydrophobicContact CE1-CG 3.73Å; Y184-Y245 HydrophobicContact CG-CD2 4.12Å; Y184-W249 AromaticContact CE1-NE1 3.73Å; Y184-W249 AromaticContact CZ-NE1 3.9Å; Y184-W249 VanDerWaalsContact OH-CD1 3.32Å; Y184-W249 PolarHBondContact OH-NE1 2.92Å
185	F	93.6	Very high	91.3	Very high	78 Å²	78	43.7 Å²	43.7	34%	0.342	22%	0.22	S	C	.	.	H	α-helix	trans	-64.9	-43.6	178.4	-71.3	-69.9	0	0	0	112.3	D181 L182 L187 C189 Y245 W249	D181-F185 VanDerWaalsContact O-CD2 3.24Å; D181-F185 WeakPolarHBondContact O-CD2 3.33Å; D181-F185 PolarHBondContact O-N 3.42Å; L182-F185 PolarHBondContact O-N 3.34Å; F185-L187 VanDerWaalsContact C-N 3.33Å; F185-L187 PolarHBondContact O-N 3.21Å; F185-C189 VanDerWaalsContact O-CB 3.27Å; F185-C189 WeakPolarHBondContact O-CB 3.37Å; F185-C189 PolarHBondContact O-N 3.2Å; F185-C189 VanDerWaalsContact O-N 3.13Å; F185-C189 PolarHBondContact O-SG 3.5Å; F185-Y245 HydrophobicContact CE2-CE1 4.12Å; F185-Y245 HydrophobicContact CE2-CE2 4.18Å; F185-Y245 AromaticContact CE2-CZ 3.88Å; F185-Y245 AromaticContact CZ-CD1 3.99Å; F185-Y245 HydrophobicContact CZ-CD1 3.99Å; F185-Y245 AromaticContact CZ-CE1 3.81Å; F185-Y245 HydrophobicContact CZ-CE1 3.81Å; F185-Y245 HydrophobicContact CZ-CE2 4.38Å; F185-Y245 HydrophobicContact CZ-CG 4.36Å; F185-W249 HydrophobicContact CD1-CZ2 4.17Å; F185-W249 AromaticContact CE1-CZ2 3.95Å; F185-W249 HydrophobicContact CE1-CZ2 3.95Å
186	C	94.1	Very high	91.1	Very high	23 Å²	23	37.5 Å²	37.5	16%	0.155	19%	0.187	C	C	.	.	H	α-helix	trans	-58.6	-42.8	178.6	-72.5	0	0	0	0	112.6	M154 L182 L183	M154-C186 VanDerWaalsContact CA-O 3.25Å; M154-C186 WeakPolarHBondContact CA-O 3.37Å; M154-C186 WeakPolarHBondContact CB-O 3.38Å; M154-C186 PolarHBondContact N-O 3.04Å; L182-C186 PolarHBondContact O-N 2.63Å; L182-C186 PolarHBondContact O-SG 2.92Å; L183-C186 PolarHBondContact O-N 3.13Å
187	L	93.7	Very high	91.4	Very high	0 Å²	0	33.5 Å²	33.5	0%	0	17%	0.17	C	C	.	.	H	α-helix	trans	-80.6	-35.6	-175.7	-66.6	175.3	0	0	0	113.4	M154 I158 L161 L183 Y184 F185 F191 V234 F237 L238	M154-L187 HydrophobicContact CG-CD2 4.08Å; I158-L187 HydrophobicContact CG1-CD2 4.28Å; L161-L187 HydrophobicContact CD1-CD1 3.66Å; L161-L187 HydrophobicContact CD1-CD2 4.43Å; L183-L187 HydrophobicContact CD2-CD1 3.42Å; L183-L187 VanDerWaalsContact CD2-CD1 3.42Å; L183-L187 HydrophobicContact CD2-CG 4.35Å; L183-L187 HydrophobicContact CG-CD1 3.99Å; L183-L187 WeakPolarHBondContact O-CG 3.15Å; L183-L187 PolarHBondContact O-N 3.05Å; Y184-L187 PolarHBondContact O-N 3.08Å; F185-L187 VanDerWaalsContact C-N 3.33Å; F185-L187 PolarHBondContact O-N 3.21Å; L187-F191 WeakPolarHBondContact O-CD2 3.46Å; L187-F191 VanDerWaalsContact O-CE2 3.31Å; L187-F191 WeakPolarHBondContact O-CE2 3.49Å; L187-V234 HydrophobicContact CB-CG1 3.91Å; L187-V234 HydrophobicContact CD1-CG1 4.41Å; L187-F237 HydrophobicContact CD1-CE2 3.84Å; L187-F237 HydrophobicContact CD1-CZ 4.23Å; L187-L238 HydrophobicContact CB-CD1 4.11Å; L187-L238 HydrophobicContact CD1-CD1 4.03Å; L187-L238 HydrophobicContact CD1-CD2 4.4Å
188	L	94.3	Very high	91.5	Very high	2 Å²	2	31.2 Å²	31.2	1%	0.01	16%	0.157	C	C	.	.	H	α-helix	trans	-84.8	-35.3	-175.7	-70.3	172.3	0	0	0	114	Y184 A190 F191 L192 M231 V234 I235 L238	Y184-L188 HydrophobicContact CD1-CD1 4.07Å; Y184-L188 HydrophobicContact CD2-CD1 3.38Å; Y184-L188 HydrophobicContact CD2-CG 4.44Å; Y184-L188 HydrophobicContact CE1-CD1 3.67Å; Y184-L188 HydrophobicContact CE2-CD1 2.93Å; Y184-L188 HydrophobicContact CE2-CG 4.29Å; Y184-L188 HydrophobicContact CG-CD1 3.94Å; Y184-L188 WeakPolarHBondContact O-CB 3.33Å; Y184-L188 PolarHBondContact O-N 3.49Å; Y184-L188 WeakPolarHBondContact OH-CD1 3.5Å; L188-A190 PolarHBondContact O-N 3Å; L188-A190 VanDerWaalsContact O-N 3.13Å; L188-F191 PolarHBondContact O-N 3.08Å; L188-L192 WeakPolarHBondContact O-CG 3.45Å; L188-L192 PolarHBondContact O-N 3.24Å; L188-L192 VanDerWaalsContact O-N 3.07Å; L188-M231 HydrophobicContact CB-SD 4.45Å; L188-M231 HydrophobicContact CD2-CE 3.85Å; L188-M231 HydrophobicContact CD2-SD 3.31Å; L188-M231 WeakPolarHBondContact CD2-SD 3.24Å; L188-M231 HydrophobicContact CG-SD 4.43Å; L188-V234 HydrophobicContact CD2-CG1 4.27Å; L188-I235 HydrophobicContact CD2-CG1 4.15Å; L188-L238 HydrophobicContact CG-CD1 4.34Å
189	C	93.5	Very high	91.8	Very high	37 Å²	37	36.2 Å²	36.2	25%	0.25	18%	0.184	C	C	.	.	H	α-helix	trans	-55.2	-38.1	-174	-75.6	0	0	0	0	112.4	V150 F185 F191 L192 V193	V150-C189 HydrophobicContact CG1-CB 3.48Å; V150-C189 VanDerWaalsContact CG1-CB 3.48Å; V150-C189 WeakPolarHBondContact CG1-O 3.46Å; F185-C189 VanDerWaalsContact O-CB 3.27Å; F185-C189 WeakPolarHBondContact O-CB 3.37Å; F185-C189 PolarHBondContact O-N 3.2Å; F185-C189 VanDerWaalsContact O-N 3.13Å; F185-C189 PolarHBondContact O-SG 3.5Å; C189-F191 VanDerWaalsContact C-N 3.29Å; C189-F191 PolarHBondContact O-N 3.44Å; C189-L192 PolarHBondContact O-N 3.34Å; C189-V193 WeakPolarHBondContact O-CG2 3.49Å; C189-V193 PolarHBondContact O-N 3.37Å
190	A	93.8	Very high	92.1	Very high	4 Å²	4	33.9 Å²	33.9	3%	0.033	17%	0.173	C	C	.	.	H	α-helix	trans	-60.1	-40	179.5	0	0	0	0	0	112.3	M154 L188 K194	M154-A190 HydrophobicContact CB-CB 3.98Å; M154-A190 HydrophobicContact CG-CB 4.43Å; M154-A190 HydrophobicContact SD-CB 3.79Å; L188-A190 PolarHBondContact O-N 3Å; L188-A190 VanDerWaalsContact O-N 3.13Å; A190-K194 PolarHBondContact O-N 3.32Å
191	F	94.4	Very high	92.3	Very high	0 Å²	0	29.7 Å²	29.7	0%	0	16%	0.157	C	C	.	.	H	α-helix	trans	-77.2	-31.6	177.8	-54.7	-53.6	0	0	0	113	F112 F116 M154 L187 L188 C189 V193 K194 M195 G230 M231 V234	F112-F191 AromaticContact CE1-CE1 3.62Å; F112-F191 HydrophobicContact CE1-CE1 3.62Å; F112-F191 AromaticContact CE1-CZ 3.72Å; F112-F191 HydrophobicContact CE1-CZ 3.72Å; F112-F191 HydrophobicContact CZ-CE1 4.04Å; F112-F191 HydrophobicContact CZ-CZ 4.48Å; F116-F191 HydrophobicContact CE2-CD1 4.27Å; F116-F191 HydrophobicContact CE2-CE1 4.3Å; F116-F191 HydrophobicContact CZ-CD1 4.05Å; F116-F191 HydrophobicContact CZ-CE1 4.17Å; M154-F191 HydrophobicContact CE-CE1 4.07Å; M154-F191 HydrophobicContact CE-CE2 4.18Å; M154-F191 HydrophobicContact CE-CZ 3.42Å; M154-F191 VanDerWaalsContact CE-CZ 3.42Å; M154-F191 HydrophobicContact SD-CE1 4.26Å; M154-F191 HydrophobicContact SD-CE2 4.46Å; M154-F191 HydrophobicContact SD-CZ 3.94Å; L187-F191 WeakPolarHBondContact O-CD2 3.46Å; L187-F191 VanDerWaalsContact O-CE2 3.31Å; L187-F191 WeakPolarHBondContact O-CE2 3.49Å; L188-F191 PolarHBondContact O-N 3.08Å; C189-F191 VanDerWaalsContact C-N 3.29Å; C189-F191 PolarHBondContact O-N 3.44Å; F191-V193 PolarHBondContact O-N 3.37Å; F191-K194 PolarHBondContact O-N 3.03Å; F191-M195 WeakPolarHBondContact O-CB 3.31Å; F191-M195 PolarHBondContact O-N 3.49Å; F191-G230 VanDerWaalsContact CE1-CA 3.49Å; F191-M231 HydrophobicContact CB-CG 3.51Å; F191-M231 HydrophobicContact CB-SD 3.47Å; F191-M231 WeakPolarHBondContact CB-SD 3.31Å; F191-M231 HydrophobicContact CD2-CG 4.25Å; F191-M231 HydrophobicContact CD2-SD 3.83Å; F191-M231 HydrophobicContact CG-CG 4.11Å; F191-M231 HydrophobicContact CG-SD 4.08Å; F191-V234 HydrophobicContact CE2-CB 3.97Å; F191-V234 HydrophobicContact CE2-CG1 4.4Å; F191-V234 HydrophobicContact CE2-CG2 3.59Å; F191-V234 HydrophobicContact CZ-CG2 3.99Å
192	L	94.6	Very high	92.4	Very high	6 Å²	6	30.4 Å²	30.4	3%	0.031	16%	0.16	C	C	.	.	H	α-helix	trans	-64.9	-23.7	174.2	-64.3	178.4	0	0	0	113.1	L188 C189 M195 M197 M231 W249 L286	L188-L192 WeakPolarHBondContact O-CG 3.45Å; L188-L192 PolarHBondContact O-N 3.24Å; L188-L192 VanDerWaalsContact O-N 3.07Å; C189-L192 PolarHBondContact O-N 3.34Å; L192-M195 CarbonylContact C-O 3.6Å; L192-M195 CarbonylContact O-C 3.53Å; L192-M197 HydrophobicContact CD1-CE 4.06Å; L192-M197 HydrophobicContact CD2-CE 3.64Å; L192-M197 HydrophobicContact CG-CE 4.33Å; L192-M197 PolarHBondContact O-N 3.08Å; L192-M197 VanDerWaalsContact O-N 3.17Å; L192-M231 HydrophobicContact CD2-CE 3.53Å; L192-M231 HydrophobicContact CG-CE 4.25Å; L192-W249 HydrophobicContact CD1-CD2 3.92Å; L192-W249 HydrophobicContact CD1-CE3 3.95Å; L192-W249 HydrophobicContact CD1-CH2 3.59Å; L192-W249 HydrophobicContact CD1-CZ2 3.61Å; L192-W249 HydrophobicContact CD1-CZ3 3.77Å; L192-L286 HydrophobicContact CD2-CD1 3.72Å; L192-L286 HydrophobicContact CD2-CG 4.43Å
193	V	94.2	Very high	92.5	Very high	7 Å²	7	24.1 Å²	24.1	4%	0.042	13%	0.127	C	C	.	.	H	α-helix	trans	-78.5	-41	171.7	179.5	0	0	0	0	111.5	V150 C189 F191 V200 W203	V150-V193 HydrophobicContact CB-CG2 3.93Å; V150-V193 HydrophobicContact CG1-CG2 3.94Å; V150-V193 HydrophobicContact CG2-CG2 3.76Å; C189-V193 WeakPolarHBondContact O-CG2 3.49Å; C189-V193 PolarHBondContact O-N 3.37Å; F191-V193 PolarHBondContact O-N 3.37Å; V193-V200 HydrophobicContact CB-CG1 4.36Å; V193-V200 HydrophobicContact CG1-CG1 4.01Å; V193-V200 HydrophobicContact CG2-CG1 3.83Å; V193-W203 WeakPolarHBondContact O-CZ2 3.39Å; V193-W203 PolarHBondContact O-NE1 2.94Å
194	K	92.2	Very high	92.5	Very high	4 Å²	4	23.8 Å²	23.8	2%	0.017	13%	0.125	C	C	.	.	H	α-helix	trans	-72.6	-40.2	178.8	-67.7	-73.4	-173.6	144.5	0	113.2	F116 L120 T147 A190 F191 P196 L224	F116-K194 HydrophobicContact CE1-CG 4.38Å; F116-K194 HydrophobicContact CE2-CD 4.35Å; F116-K194 HydrophobicContact CE2-CG 3.89Å; F116-K194 HydrophobicContact CZ-CB 4.45Å; F116-K194 HydrophobicContact CZ-CD 4.04Å; F116-K194 HydrophobicContact CZ-CG 3.43Å; F116-K194 VanDerWaalsContact CZ-CG 3.43Å; L120-K194 VanDerWaalsContact CG-NZ 3.29Å; T147-K194 HydrophobicContact CG2-CD 3.81Å; T147-K194 VanDerWaalsContact CG2-CE 3.49Å; A190-K194 PolarHBondContact O-N 3.32Å; F191-K194 PolarHBondContact O-N 3.03Å; K194-P196 WeakPolarHBondContact O-CD 3.49Å; K194-L224 WeakPolarHBondContact O-CD2 3.38Å
195	M	89.4	Confident	92.5	Very high	2 Å²	2	24.2 Å²	24.2	1%	0.01	13%	0.128	C	C	.	.	T	Hydrogen-bonded Turn	trans	-86.3	88.2	165.2	-75.2	-71.1	-78.7	0	0	106.2	F191 L192 M197 G227 M282 V285 L286 L289	F191-M195 WeakPolarHBondContact O-CB 3.31Å; F191-M195 PolarHBondContact O-N 3.49Å; L192-M195 CarbonylContact C-O 3.6Å; L192-M195 CarbonylContact O-C 3.53Å; M195-M197 VanDerWaalsContact C-N 3.34Å; M195-M197 PolarHBondContact O-N 3.48Å; M195-G227 VanDerWaalsContact CG-C 3.46Å; M195-M282 HydrophobicContact CE-CB 4.35Å; M195-M282 HydrophobicContact CE-SD 3.69Å; M195-M282 HydrophobicContact SD-SD 3.86Å; M195-V285 HydrophobicContact CE-CB 4.03Å; M195-V285 HydrophobicContact CE-CG1 3.65Å; M195-L286 HydrophobicContact CB-CD1 4.2Å; M195-L289 HydrophobicContact CE-CD1 4.43Å
196	P	81	Confident	92.4	Very high	3 Å²	3	24.6 Å²	24.6	2%	0.019	13%	0.13	C	C	.	.	T	Hydrogen-bonded Turn	trans	-55.4	94.2	-161.8	29.4	-42.3	0	0	0	110.6	K194 H201 L204 L224 V279	K194-P196 WeakPolarHBondContact O-CD 3.49Å; P196-H201 HydrophobicContact CB-CB 3.79Å; P196-L204 HydrophobicContact CB-CD1 3.96Å; P196-L204 HydrophobicContact CG-CD1 3.52Å; P196-L224 HydrophobicContact CG-CD2 4.26Å; P196-V279 HydrophobicContact CB-CG2 4.25Å; P196-V279 HydrophobicContact CG-CG2 4.02Å
197	M	91.2	Very high	92.5	Very high	10 Å²	10	23.5 Å²	23.5	5%	0.049	12%	0.122	C	C	.	.			trans	-65.5	146.8	170.6	-175	-178.1	-89.3	0	0	107.9	L192 M195 V200 H201 W249 I252 L286	L192-M197 HydrophobicContact CD1-CE 4.06Å; L192-M197 HydrophobicContact CD2-CE 3.64Å; L192-M197 HydrophobicContact CG-CE 4.33Å; L192-M197 PolarHBondContact O-N 3.08Å; L192-M197 VanDerWaalsContact O-N 3.17Å; M195-M197 VanDerWaalsContact C-N 3.34Å; M195-M197 PolarHBondContact O-N 3.48Å; M197-V200 CarbonylContact O-C 3.56Å; M197-V200 PolarHBondContact O-N 3.14Å; M197-H201 PolarHBondContact O-N 3.38Å; M197-W249 HydrophobicContact CE-CB 3.88Å; M197-W249 HydrophobicContact CE-CD2 3.77Å; M197-W249 HydrophobicContact CE-CE3 3.14Å; M197-W249 HydrophobicContact CE-CG 4.11Å; M197-W249 HydrophobicContact CE-CZ3 3.84Å; M197-W249 HydrophobicContact SD-CE3 3.45Å; M197-W249 HydrophobicContact SD-CZ3 3.6Å; M197-I252 HydrophobicContact CG-CG2 3.78Å; M197-I252 HydrophobicContact SD-CB 4.38Å; M197-I252 HydrophobicContact SD-CG2 3.81Å; M197-L286 HydrophobicContact CE-CD1 4.31Å; M197-L286 HydrophobicContact CE-CD2 3.77Å
198	F	87.4	Confident	92.5	Very high	51 Å²	51	23.5 Å²	23.5	22%	0.224	12%	0.122	C	C	.	.	T	Hydrogen-bonded Turn	trans	-50.7	146.9	165.7	-170.4	-108	0	0	0	110.3	V200 H201 I252 G256 L259 V260	F198-V200 VanDerWaalsContact C-N 3.32Å; F198-V200 PolarHBondContact O-N 3.35Å; F198-H201 AromaticContact CD2-CE1 3.9Å; F198-I252 HydrophobicContact CB-CG2 4.21Å; F198-G256 VanDerWaalsContact CB-CA 3.49Å; F198-G256 VanDerWaalsContact CD2-CA 3.42Å; F198-G256 WeakPolarHBondContact CD2-O 3.38Å; F198-L259 HydrophobicContact CE1-CD1 3.81Å; F198-L259 HydrophobicContact CE2-CB 3.97Å; F198-L259 HydrophobicContact CE2-CD1 4.29Å; F198-L259 HydrophobicContact CZ-CB 3.99Å; F198-L259 HydrophobicContact CZ-CD1 3.49Å; F198-L259 VanDerWaalsContact CZ-CD1 3.49Å; F198-L259 HydrophobicContact CZ-CG 4.4Å; F198-V260 HydrophobicContact CD2-CG2 3.75Å; F198-V260 HydrophobicContact CE2-CG2 3.99Å
199	L	93.2	Very high	92.4	Very high	119 Å²	119	24.1 Å²	24.1	62%	0.623	13%	0.126	S	C	*	.	T	Hydrogen-bonded Turn	trans	81.1	-46.2	-161.7	-48.3	170.1	0	0	0	115.5	H201	L199-H201 PolarHBondContact N-ND1 3.3Å
200	V	92.9	Very high	92.4	Very high	45 Å²	45	22.6 Å²	22.6	27%	0.273	12%	0.115	S	C	.	.	T	Hydrogen-bonded Turn	trans	-102.1	2	-174.9	-153.9	0	0	0	0	113.2	Y146 V193 M197 F198 L202 W203	Y146-V200 HydrophobicContact CD1-CG1 3.57Å; Y146-V200 HydrophobicContact CE1-CG1 3.83Å; V193-V200 HydrophobicContact CB-CG1 4.36Å; V193-V200 HydrophobicContact CG1-CG1 4.01Å; V193-V200 HydrophobicContact CG2-CG1 3.83Å; M197-V200 CarbonylContact O-C 3.56Å; M197-V200 PolarHBondContact O-N 3.14Å; F198-V200 VanDerWaalsContact C-N 3.32Å; F198-V200 PolarHBondContact O-N 3.35Å; V200-L202 VanDerWaalsContact C-N 3.32Å; V200-L202 PolarHBondContact O-N 3.45Å; V200-W203 PolarHBondContact O-NE1 3.3Å
201	H	94.1	Very high	92.4	Very high	18 Å²	18	22.4 Å²	22.4	8%	0.083	11%	0.113	C	C	.	.	T	Hydrogen-bonded Turn	trans	-72	-11	-177.4	68.6	-73.9	0	0	0	116.3	P196 M197 F198 L199 W203 L204 P205 V279	P196-H201 HydrophobicContact CB-CB 3.79Å; M197-H201 PolarHBondContact O-N 3.38Å; F198-H201 AromaticContact CD2-CE1 3.9Å; L199-H201 PolarHBondContact N-ND1 3.3Å; H201-W203 PolarHBondContact O-N 3.32Å; H201-W203 VanDerWaalsContact O-N 3.1Å; H201-L204 WeakPolarHBondContact O-CB 3.31Å; H201-L204 PolarHBondContact O-N 3.39Å; H201-P205 WeakPolarHBondContact O-CD 3.49Å; H201-V279 HydrophobicContact CB-CG1 3.89Å; H201-V279 HydrophobicContact CB-CG2 4.11Å
202	L	93.1	Very high	92.4	Very high	87 Å²	87	22.5 Å²	22.5	46%	0.455	11%	0.114	S	C	.	.	T	Hydrogen-bonded Turn	trans	-62.1	-23.6	-168.4	-68.1	175.6	0	0	0	114.8	V200 L204	V200-L202 VanDerWaalsContact C-N 3.32Å; V200-L202 PolarHBondContact O-N 3.45Å; L202-L204 VanDerWaalsContact C-N 3.27Å; L202-L204 PolarHBondContact O-N 3.03Å
203	W	94.4	Very high	92.3	Very high	4 Å²	4	22.5 Å²	22.5	2%	0.015	12%	0.115	C	C	.	.	H	α-helix	trans	-67	-31.4	175.6	67.8	-96.2	0	0	0	111.8	L143 Y146 V193 V200 H201 A207 L219 L224	L143-W203 HydrophobicContact CD1-CD2 4.31Å; L143-W203 HydrophobicContact CD1-CE3 3.38Å; L143-W203 HydrophobicContact CD1-CH2 4.25Å; L143-W203 HydrophobicContact CD1-CZ3 3.34Å; Y146-W203 HydrophobicContact CD2-CB 4.13Å; Y146-W203 HydrophobicContact CG-CB 4.21Å; Y146-W203 HydrophobicContact CG-CG 4.47Å; V193-W203 WeakPolarHBondContact O-CZ2 3.39Å; V193-W203 PolarHBondContact O-NE1 2.94Å; V200-W203 PolarHBondContact O-NE1 3.3Å; H201-W203 PolarHBondContact O-N 3.32Å; H201-W203 VanDerWaalsContact O-N 3.1Å; W203-A207 HydrophobicContact CE3-CB 4.21Å; W203-A207 VanDerWaalsContact O-CB 3.25Å; W203-A207 WeakPolarHBondContact O-CB 3.42Å; W203-A207 PolarHBondContact O-N 3.39Å; W203-L219 HydrophobicContact CZ3-CD2 4.44Å; W203-L224 HydrophobicContact CH2-CD2 3.95Å; W203-L224 HydrophobicContact CZ2-CD2 4.31Å
204	L	93	Very high	92.3	Very high	0 Å²	0	22.2 Å²	22.2	0%	0	11%	0.113	C	C	.	.	H	α-helix	trans	-68.9	-53.5	-171	-175.9	166.5	0	0	0	112.1	P196 H201 L202 K206 A207 H208 L224 A275 V279	P196-L204 HydrophobicContact CB-CD1 3.96Å; P196-L204 HydrophobicContact CG-CD1 3.52Å; H201-L204 WeakPolarHBondContact O-CB 3.31Å; H201-L204 PolarHBondContact O-N 3.39Å; L202-L204 VanDerWaalsContact C-N 3.27Å; L202-L204 PolarHBondContact O-N 3.03Å; L204-K206 VanDerWaalsContact C-N 3.27Å; L204-K206 PolarHBondContact O-N 2.64Å; L204-A207 PolarHBondContact O-N 2.92Å; L204-H208 WeakPolarHBondContact CD2-CD2 3.33Å; L204-H208 PolarHBondContact O-CD2 3.31Å; L204-H208 VanDerWaalsContact O-CD2 3.28Å; L204-H208 PolarHBondContact O-N 3.34Å; L204-L224 HydrophobicContact CD1-CD1 4Å; L204-L224 HydrophobicContact CD1-CD2 3.49Å; L204-L224 VanDerWaalsContact CD1-CD2 3.49Å; L204-L224 HydrophobicContact CD1-CG 4.39Å; L204-L224 HydrophobicContact CG-CD2 4.47Å; L204-A275 HydrophobicContact CD2-CB 3.74Å; L204-A275 WeakPolarHBondContact CD2-O 3.45Å; L204-V279 HydrophobicContact CD1-CG2 3.87Å; L204-V279 HydrophobicContact CD2-CG2 4.09Å; L204-V279 HydrophobicContact CG-CG2 4.46Å
205	P	93.2	Very high	92.4	Very high	8 Å²	8	22.3 Å²	22.3	5%	0.052	12%	0.115	C	C	.	.	H	α-helix	trans	-55.8	-41.8	177.9	-26.6	34.4	0	0	0	112.7	H201 V209 Y276	H201-P205 WeakPolarHBondContact O-CD 3.49Å; P205-V209 VanDerWaalsContact O-CB 3.3Å; P205-V209 WeakPolarHBondContact O-CB 3.37Å; P205-V209 WeakPolarHBondContact O-CG2 3.49Å; P205-V209 PolarHBondContact O-N 3.16Å; P205-Y276 HydrophobicContact CB-CE1 4.31Å; P205-Y276 HydrophobicContact CB-CE2 3.98Å; P205-Y276 HydrophobicContact CG-CD1 3.94Å; P205-Y276 HydrophobicContact CG-CD2 4.45Å; P205-Y276 HydrophobicContact CG-CE1 3.46Å; P205-Y276 VanDerWaalsContact CG-CE1 3.46Å; P205-Y276 HydrophobicContact CG-CE2 4Å; P205-Y276 HydrophobicContact CG-CG 4.41Å; P205-Y276 VanDerWaalsContact CG-CZ 3.48Å
206	K	93	Very high	92.7	Very high	87 Å²	87	22.2 Å²	22.2	38%	0.378	11%	0.114	S	C	.	.	H	α-helix	trans	-65.9	-45.3	178	-65.3	-173.5	-179.9	-175.3	0	111.9	A139 Y142 L204 H208 E210	A139-K206 HydrophobicContact CB-CB 4.21Å; Y142-K206 HydrophobicContact CD2-CD 3.56Å; Y142-K206 HydrophobicContact CE2-CD 3.56Å; L204-K206 VanDerWaalsContact C-N 3.27Å; L204-K206 PolarHBondContact O-N 2.64Å; K206-H208 PolarHBondContact O-N 3.06Å; K206-E210 PolarHBondContact O-N 3.41Å
207	A	94.7	Very high	93.5	Very high	0 Å²	0	22.1 Å²	22.1	0%	0	11%	0.113	C	C	.	.	H	α-helix	trans	-62.3	-44.3	179.1	0	0	0	0	0	112.1	W203 L204 A211 L219	W203-A207 HydrophobicContact CE3-CB 4.21Å; W203-A207 VanDerWaalsContact O-CB 3.25Å; W203-A207 WeakPolarHBondContact O-CB 3.42Å; W203-A207 PolarHBondContact O-N 3.39Å; L204-A207 PolarHBondContact O-N 2.92Å; A207-A211 WeakPolarHBondContact O-CB 3.49Å; A207-A211 PolarHBondContact O-N 3Å; A207-L219 HydrophobicContact CB-CD1 4.05Å
208	H	94.2	Very high	93.7	Very high	0 Å²	0	21.7 Å²	21.7	0%	0	11%	0.111	C	C	.	.	H	α-helix	trans	-69.7	-39.4	-180	-84	-79.9	0	0	0	114.1	L204 K206 E210 S216 L219 A220 A275 F315	L204-H208 WeakPolarHBondContact CD2-CD2 3.33Å; L204-H208 PolarHBondContact O-CD2 3.31Å; L204-H208 VanDerWaalsContact O-CD2 3.28Å; L204-H208 PolarHBondContact O-N 3.34Å; K206-H208 PolarHBondContact O-N 3.06Å; H208-E210 VanDerWaalsContact C-N 3.32Å; H208-S216 PolarHBondContact CE1-O 3.25Å; H208-S216 VanDerWaalsContact CE1-O 3.27Å; H208-S216 PolarHBondContact ND1-O 3.17Å; H208-S216 PolarHBondContact O-OG 2.96Å; H208-S216 VanDerWaalsContact O-OG 3.12Å; H208-L219 WeakPolarHBondContact CE1-CB 3.39Å; H208-A220 PolarHBondContact CE1-N 3.4Å; H208-A220 VanDerWaalsContact CE1-N 3.31Å; H208-A275 HydrophobicContact CB-CB 3.86Å; H208-F315 HydrophobicContact CB-CE1 4.09Å; H208-F315 HydrophobicContact CB-CZ 4.01Å; H208-F315 AromaticContact CE1-CE2 3.8Å; H208-F315 AromaticContact CE1-CZ 3.92Å; H208-F315 AromaticContact CG-CZ 3.7Å; H208-F315 AromaticContact ND1-CE1 3.81Å; H208-F315 AromaticContact ND1-CE2 3.51Å; H208-F315 AromaticContact ND1-CZ 3.23Å; H208-F315 WeakPolarHBondContact ND1-CZ 3.49Å
209	V	92.8	Very high	94.1	Very high	14 Å²	14	19.4 Å²	19.4	9%	0.085	10%	0.101	C	C	.	.	H	α-helix	trans	-68.5	-37.6	-176.3	172.3	0	0	0	0	110.7	P205 K271 A272 R328	P205-V209 VanDerWaalsContact O-CB 3.3Å; P205-V209 WeakPolarHBondContact O-CB 3.37Å; P205-V209 WeakPolarHBondContact O-CG2 3.49Å; P205-V209 PolarHBondContact O-N 3.16Å; V209-K271 HydrophobicContact CG2-CB 4.08Å; V209-A272 HydrophobicContact CG2-CB 3.78Å; V209-R328 PolarHBondContact O-NH1 3.28Å
210	E	93.1	Very high	94.2	Very high	5 Å²	5	13.7 Å²	13.7	2%	0.023	7%	0.072	C	C	.	.	H	α-helix	trans	-91.4	-21.7	-177.2	-63.9	-47.7	124	0	0	115.2	G131 Q133 E135 R136 A139 K206 H208 R328	G131-E210 VanDerWaalsContact CA-O 3.28Å; G131-E210 WeakPolarHBondContact CA-O 3.28Å; Q133-E210 WeakPolarHBondContact CB-OE2 2.98Å; Q133-E210 VanDerWaalsContact CG-OE2 3.32Å; Q133-E210 WeakPolarHBondContact CG-OE2 3.21Å; Q133-E210 PolarHBondContact OE1-OE1 2.96Å; E135-E210 HydrophobicContact CB-CG 4.07Å; R136-E210 HydrophobicContact CB-CB 4.2Å; A139-E210 HydrophobicContact CB-CB 4.04Å; A139-E210 HydrophobicContact CB-CG 4.18Å; K206-E210 PolarHBondContact O-N 3.41Å; H208-E210 VanDerWaalsContact C-N 3.32Å; E210-R328 IonicContact OE1-CZ 3.71Å; E210-R328 IonicContact OE1-NH1 3.48Å; E210-R328 PolarHBondContact OE1-NH1 3.14Å; E210-R328 IonicContact OE1-NH2 2.82Å; E210-R328 PolarHBondContact OE1-NH2 3.11Å; E210-R328 IonicContact OE2-NH1 3.23Å
211	A	94	Very high	94.3	Very high	0 Å²	0	11.6 Å²	11.6	0%	0	6%	0.059	C	C	.	.	S	Bend	trans	-62.2	149.5	175	0	0	0	0	0	111.9	I127 A207 L219 K271	I127-A211 HydrophobicContact CG1-CB 4.06Å; A207-A211 WeakPolarHBondContact O-CB 3.49Å; A207-A211 PolarHBondContact O-N 3Å; A211-L219 HydrophobicContact CB-CD1 4.4Å; A211-K271 PolarHBondContact O-NZ 3.33Å
212	P	93.9	Very high	94.4	Very high	3 Å²	3	10.8 Å²	10.8	2%	0.019	6%	0.055	C	C	.	.			trans	-59.1	167	160.1	30.5	-36.1	0	0	0	109.8	L126 W130 S214 G215 S216	L126-P212 WeakPolarHBondContact O-CD 3.29Å; L126-P212 WeakPolarHBondContact O-CG 3.09Å; W130-P212 HydrophobicContact CB-CB 4.12Å; W130-P212 HydrophobicContact CB-CG 4.05Å; P212-S214 PolarHBondContact O-N 2.98Å; P212-G215 PolarHBondContact O-N 2.82Å; P212-G215 VanDerWaalsContact O-N 3.09Å; P212-S216 PolarHBondContact O-N 3.44Å; P212-S216 PolarHBondContact O-OG 2.9Å
213	V	94.2	Very high	94.5	Very high	6 Å²	6	6.8 Å²	6.8	4%	0.036	3%	0.034	C	C	.	.	H	α-helix	trans	-53.6	-45.6	179	-164	0	0	0	0	111.4	A75 G215 S216 M217 N319	A75-V213 HydrophobicContact CB-CG1 3.99Å; V213-G215 PolarHBondContact O-N 3.34Å; V213-S216 WeakPolarHBondContact O-CB 3.47Å; V213-S216 PolarHBondContact O-N 3.38Å; V213-M217 HydrophobicContact CG1-CG 4.45Å; V213-M217 HydrophobicContact CG1-SD 4.11Å; V213-M217 WeakPolarHBondContact O-CB 3.39Å; V213-M217 VanDerWaalsContact O-CG 3.26Å; V213-M217 WeakPolarHBondContact O-CG 3.14Å; V213-M217 PolarHBondContact O-N 3.47Å; V213-N319 HydrophobicContact CB-CB 4.26Å; V213-N319 HydrophobicContact CG1-CB 3.66Å; V213-N319 HydrophobicContact CG2-CB 3.59Å; V213-N319 VanDerWaalsContact CG2-ND2 3.34Å; V213-N319 WeakPolarHBondContact CG2-ND2 3.33Å; V213-N319 WeakPolarHBondContact CG2-OD1 3.39Å
214	S	93.9	Very high	94.4	Very high	1 Å²	1	6.6 Å²	6.6	1%	0.007	3%	0.034	C	C	.	.	H	α-helix	trans	-57.2	-48.1	176.7	45.4	0	0	0	0	112.2	M72 F89 P212 M217 I218	M72-S214 VanDerWaalsContact CE-CB 3.46Å; F89-S214 WeakPolarHBondContact CE2-OG 3.45Å; P212-S214 PolarHBondContact O-N 2.98Å; S214-M217 PolarHBondContact O-N 3.26Å; S214-I218 WeakPolarHBondContact O-CD1 3.26Å; S214-I218 WeakPolarHBondContact O-CG1 3.35Å; S214-I218 PolarHBondContact O-N 3.26Å; S214-I218 VanDerWaalsContact O-N 3.11Å
215	G	94.6	Very high	94.6	Very high	5 Å²	5	6.6 Å²	6.6	5%	0.052	3%	0.034	C	C	.	.	H	α-helix	trans	-63.3	-42.9	175.5	0	0	0	0	0	112.3	P212 V213 M217 I218 L219	P212-G215 PolarHBondContact O-N 2.82Å; P212-G215 VanDerWaalsContact O-N 3.09Å; V213-G215 PolarHBondContact O-N 3.34Å; G215-M217 VanDerWaalsContact C-N 3.35Å; G215-M217 PolarHBondContact O-N 3.47Å; G215-I218 PolarHBondContact O-N 3.14Å; G215-L219 VanDerWaalsContact O-CB 3.31Å; G215-L219 WeakPolarHBondContact O-CB 3.36Å; G215-L219 VanDerWaalsContact O-CG 3.24Å; G215-L219 WeakPolarHBondContact O-CG 3.48Å; G215-L219 PolarHBondContact O-N 3.3Å
216	S	95.7	Very high	94.7	Very high	1 Å²	1	6.2 Å²	6.2	1%	0.007	3%	0.031	C	C	.	.	H	α-helix	trans	-61.1	-42.9	177.4	-55.8	0	0	0	0	111.8	H208 P212 V213 A220	H208-S216 PolarHBondContact CE1-O 3.25Å; H208-S216 VanDerWaalsContact CE1-O 3.27Å; H208-S216 PolarHBondContact ND1-O 3.17Å; H208-S216 PolarHBondContact O-OG 2.96Å; H208-S216 VanDerWaalsContact O-OG 3.12Å; P212-S216 PolarHBondContact O-N 3.44Å; P212-S216 PolarHBondContact O-OG 2.9Å; V213-S216 WeakPolarHBondContact O-CB 3.47Å; V213-S216 PolarHBondContact O-N 3.38Å; S216-A220 VanDerWaalsContact O-CB 3.3Å; S216-A220 WeakPolarHBondContact O-CB 3.27Å; S216-A220 PolarHBondContact O-N 3.43Å
217	M	96.7	Very high	94.8	Very high	0 Å²	0	2.1 Å²	2.1	0%	0	1%	0.013	C	C	.	.	H	α-helix	trans	-65.7	-43	179.1	-72.1	174.2	73.3	0	0	112.2	I68 L71 A75 V213 S214 G215 G221 H428	I68-M217 HydrophobicContact CG2-CB 4.41Å; L71-M217 HydrophobicContact CB-CE 3.81Å; A75-M217 HydrophobicContact CB-SD 3.65Å; V213-M217 HydrophobicContact CG1-CG 4.45Å; V213-M217 HydrophobicContact CG1-SD 4.11Å; V213-M217 WeakPolarHBondContact O-CB 3.39Å; V213-M217 VanDerWaalsContact O-CG 3.26Å; V213-M217 WeakPolarHBondContact O-CG 3.14Å; V213-M217 PolarHBondContact O-N 3.47Å; S214-M217 PolarHBondContact O-N 3.26Å; G215-M217 VanDerWaalsContact C-N 3.35Å; G215-M217 PolarHBondContact O-N 3.47Å; M217-G221 VanDerWaalsContact O-CA 3.3Å; M217-G221 WeakPolarHBondContact O-CA 3.17Å; M217-G221 PolarHBondContact O-N 2.85Å; M217-H428 WeakPolarHBondContact CE-NE2 3.41Å
218	I	96.6	Very high	94.8	Very high	1 Å²	1	2.1 Å²	2.1	1%	0.005	1%	0.013	C	C	.	.	H	α-helix	trans	-71.8	-42.1	179.2	-62.2	156.1	0	0	0	111.5	M72 L96 L100 L126 S214 G215 A220 G221 I222 M223	M72-I218 HydrophobicContact CE-CD1 3.09Å; M72-I218 HydrophobicContact CE-CG1 3.88Å; M72-I218 HydrophobicContact SD-CD1 3.53Å; M72-I218 VanDerWaalsContact SD-CD1 3.53Å; M72-I218 HydrophobicContact SD-CG1 3.85Å; L96-I218 HydrophobicContact CD2-CB 4.47Å; L96-I218 HydrophobicContact CD2-CD1 3.33Å; L96-I218 HydrophobicContact CD2-CG1 4.24Å; L96-I218 HydrophobicContact CD2-CG2 3.81Å; L100-I218 HydrophobicContact CD1-CG2 4.48Å; L126-I218 HydrophobicContact CD1-CD1 3.6Å; S214-I218 WeakPolarHBondContact O-CD1 3.26Å; S214-I218 WeakPolarHBondContact O-CG1 3.35Å; S214-I218 PolarHBondContact O-N 3.26Å; S214-I218 VanDerWaalsContact O-N 3.11Å; G215-I218 PolarHBondContact O-N 3.14Å; I218-A220 VanDerWaalsContact C-N 3.31Å; I218-A220 PolarHBondContact O-N 3.37Å; I218-G221 PolarHBondContact O-N 3.06Å; I218-I222 HydrophobicContact CG2-CD1 4.42Å; I218-I222 PolarHBondContact O-N 3.18Å; I218-M223 HydrophobicContact CG2-CG 4.01Å; I218-M223 PolarHBondContact O-N 3.27Å; I218-M223 VanDerWaalsContact O-N 3.08Å
219	L	95.7	Very high	94.8	Very high	3 Å²	3	2.1 Å²	2.1	2%	0.016	1%	0.013	C	C	.	.	I	π-helix	trans	-56.2	-50.5	176.5	-76.9	169.2	0	0	0	109.9	I127 L143 W203 A207 H208 A211 G215 M223 L224	I127-L219 HydrophobicContact CD1-CD1 4.34Å; L143-L219 HydrophobicContact CD1-CD2 4.49Å; W203-L219 HydrophobicContact CZ3-CD2 4.44Å; A207-L219 HydrophobicContact CB-CD1 4.05Å; H208-L219 WeakPolarHBondContact CE1-CB 3.39Å; A211-L219 HydrophobicContact CB-CD1 4.4Å; G215-L219 VanDerWaalsContact O-CB 3.31Å; G215-L219 WeakPolarHBondContact O-CB 3.36Å; G215-L219 VanDerWaalsContact O-CG 3.24Å; G215-L219 WeakPolarHBondContact O-CG 3.48Å; G215-L219 PolarHBondContact O-N 3.3Å; L219-M223 HydrophobicContact CD2-CB 4.19Å; L219-M223 HydrophobicContact CD2-CG 4.12Å; L219-M223 PolarHBondContact O-N 3.21Å; L219-L224 WeakPolarHBondContact O-CG 3.09Å; L219-L224 PolarHBondContact O-N 3.11Å
220	A	94.9	Very high	94.9	Very high	0 Å²	0	1.4 Å²	1.4	0%	0	1%	0.009	C	C	.	.	I	π-helix	trans	-70.5	-45.4	-178.3	0	0	0	0	0	110.7	H208 S216 I218 K225 F315	H208-A220 PolarHBondContact CE1-N 3.4Å; H208-A220 VanDerWaalsContact CE1-N 3.31Å; S216-A220 VanDerWaalsContact O-CB 3.3Å; S216-A220 WeakPolarHBondContact O-CB 3.27Å; S216-A220 PolarHBondContact O-N 3.43Å; I218-A220 VanDerWaalsContact C-N 3.31Å; I218-A220 PolarHBondContact O-N 3.37Å; A220-K225 PolarHBondContact O-NZ 3.03Å; A220-F315 HydrophobicContact CB-CD2 3.75Å; A220-F315 HydrophobicContact CB-CE2 3.61Å
221	G	94	Very high	95	Very high	0 Å²	0	1.3 Å²	1.3	0%	0	1%	0.009	C	C	.	.	I	π-helix	trans	-66.6	-49.4	-172.8	0	0	0	0	0	113.6	L64 I68 M217 I218 K225	L64-G221 WeakPolarHBondContact CD2-O 3.33Å; I68-G221 VanDerWaalsContact CD1-CA 3.46Å; M217-G221 VanDerWaalsContact O-CA 3.3Å; M217-G221 WeakPolarHBondContact O-CA 3.17Å; M217-G221 PolarHBondContact O-N 2.85Å; I218-G221 PolarHBondContact O-N 3.06Å; G221-K225 WeakPolarHBondContact O-CD 3.32Å; G221-K225 WeakPolarHBondContact O-CE 3.19Å
222	I	96.4	Very high	95	Very high	1 Å²	1	2.1 Å²	2.1	1%	0.005	1%	0.013	C	C	.	.	I	π-helix	trans	-128.2	-42.2	-163.4	-51	160.5	0	0	0	112.2	S65 I68 L100 F104 I218 L224 K225 L226	S65-I222 VanDerWaalsContact CA-CD1 3.49Å; I68-I222 HydrophobicContact CB-CD1 4.19Å; I68-I222 HydrophobicContact CD1-CG1 4.24Å; I68-I222 HydrophobicContact CG2-CD1 4.37Å; L100-I222 HydrophobicContact CD1-CB 4.49Å; L100-I222 HydrophobicContact CD1-CD1 3.82Å; L100-I222 HydrophobicContact CD1-CG2 4.06Å; L100-I222 HydrophobicContact CD2-CG2 3.8Å; L100-I222 HydrophobicContact CG-CG2 4.45Å; F104-I222 HydrophobicContact CE2-CG2 3.66Å; F104-I222 HydrophobicContact CZ-CG2 3.72Å; I218-I222 HydrophobicContact CG2-CD1 4.42Å; I218-I222 PolarHBondContact O-N 3.18Å; I222-L224 VanDerWaalsContact C-N 3.34Å; I222-L224 PolarHBondContact O-N 3.27Å; I222-K225 CarbonylContact O-C 3.55Å; I222-K225 WeakPolarHBondContact O-CA 3.28Å; I222-K225 WeakPolarHBondContact O-CB 3.34Å; I222-K225 PolarHBondContact O-N 3.5Å; I222-L226 PolarHBondContact O-N 3.45Å
223	M	95.1	Very high	95	Very high	4 Å²	4	3 Å²	3	2%	0.02	2%	0.016	C	C	.	.	I	π-helix	trans	-64.9	-36.5	-170.9	-63.3	-65.2	-68.4	0	0	113.1	L100 L120 T123 I218 L219 K225 L226	L100-M223 HydrophobicContact CD2-SD 4.21Å; L120-M223 HydrophobicContact CD2-CE 4.05Å; T123-M223 HydrophobicContact CG2-CE 3.89Å; T123-M223 HydrophobicContact CG2-CG 4.16Å; T123-M223 HydrophobicContact CG2-SD 3.86Å; I218-M223 HydrophobicContact CG2-CG 4.01Å; I218-M223 PolarHBondContact O-N 3.27Å; I218-M223 VanDerWaalsContact O-N 3.08Å; L219-M223 HydrophobicContact CD2-CB 4.19Å; L219-M223 HydrophobicContact CD2-CG 4.12Å; L219-M223 PolarHBondContact O-N 3.21Å; M223-K225 VanDerWaalsContact C-N 3.29Å; M223-L226 HydrophobicContact CE-CD1 4.1Å; M223-L226 WeakPolarHBondContact O-CB 3.35Å; M223-L226 PolarHBondContact O-N 2.91Å; M223-L226 HydrophobicContact SD-CD1 3.65Å
224	L	94	Very high	94.9	Very high	0 Å²	0	2.7 Å²	2.7	0%	0	1%	0.014	C	C	.	.	H	α-helix	trans	-63.3	-40.3	171.6	-56	175.7	0	0	0	110.6	K194 P196 W203 L204 L219 I222 L226 G227 G228 M282	K194-L224 WeakPolarHBondContact O-CD2 3.38Å; P196-L224 HydrophobicContact CG-CD2 4.26Å; W203-L224 HydrophobicContact CH2-CD2 3.95Å; W203-L224 HydrophobicContact CZ2-CD2 4.31Å; L204-L224 HydrophobicContact CD1-CD1 4Å; L204-L224 HydrophobicContact CD1-CD2 3.49Å; L204-L224 VanDerWaalsContact CD1-CD2 3.49Å; L204-L224 HydrophobicContact CD1-CG 4.39Å; L204-L224 HydrophobicContact CG-CD2 4.47Å; L219-L224 WeakPolarHBondContact O-CG 3.09Å; L219-L224 PolarHBondContact O-N 3.11Å; I222-L224 VanDerWaalsContact C-N 3.34Å; I222-L224 PolarHBondContact O-N 3.27Å; L224-L226 VanDerWaalsContact C-N 3.3Å; L224-L226 PolarHBondContact O-N 3.28Å; L224-G227 PolarHBondContact O-N 2.96Å; L224-G228 PolarHBondContact O-N 3.27Å; L224-M282 HydrophobicContact CD1-CG 4.37Å
225	K	96.3	Very high	94.9	Very high	0 Å²	0	2.8 Å²	2.8	0%	0	1%	0.014	C	C	.	.	H	α-helix	trans	-70.2	-26	-177.1	-72.3	61.8	165.7	179.5	0	112.5	L61 A220 G221 I222 M223 G227 G228 Y229 M282 M304 G308	L61-K225 HydrophobicContact CD2-CB 4.17Å; L61-K225 HydrophobicContact CD2-CG 4.46Å; A220-K225 PolarHBondContact O-NZ 3.03Å; G221-K225 WeakPolarHBondContact O-CD 3.32Å; G221-K225 WeakPolarHBondContact O-CE 3.19Å; I222-K225 CarbonylContact O-C 3.55Å; I222-K225 WeakPolarHBondContact O-CA 3.28Å; I222-K225 WeakPolarHBondContact O-CB 3.34Å; I222-K225 PolarHBondContact O-N 3.5Å; M223-K225 VanDerWaalsContact C-N 3.29Å; K225-G227 PolarHBondContact O-N 3.22Å; K225-G228 PolarHBondContact O-N 2.62Å; K225-G228 VanDerWaalsContact O-N 3.16Å; K225-Y229 WeakPolarHBondContact O-CB 3.41Å; K225-Y229 PolarHBondContact O-N 3.14Å; K225-M282 HydrophobicContact CD-CE 3.91Å; K225-M282 VanDerWaalsContact NZ-CE 3.26Å; K225-M304 HydrophobicContact CB-SD 4.41Å; K225-M304 WeakPolarHBondContact CE-O 3.38Å; K225-M304 HydrophobicContact CG-CB 3.88Å; K225-M304 HydrophobicContact CG-CG 4.1Å; K225-M304 HydrophobicContact CG-SD 4.29Å; K225-G308 VanDerWaalsContact NZ-CA 3.33Å
226	L	94.7	Very high	94.6	Very high	0 Å²	0	3.8 Å²	3.8	0%	0	2%	0.021	C	C	.	.	H	α-helix	trans	-56.6	-38.8	169.7	-71.8	173.1	0	0	0	111.6	L100 T103 F104 F116 I222 M223 L224 G230	L100-L226 HydrophobicContact CD2-CD1 3.72Å; L100-L226 HydrophobicContact CD2-CD2 4.11Å; L100-L226 HydrophobicContact CD2-CG 4.21Å; T103-L226 HydrophobicContact CG2-CD2 4.27Å; T103-L226 VanDerWaalsContact OG1-CD2 3.26Å; T103-L226 WeakPolarHBondContact OG1-CD2 3.39Å; F104-L226 HydrophobicContact CD1-CD2 4.31Å; F104-L226 HydrophobicContact CE1-CD2 3.55Å; F104-L226 HydrophobicContact CE1-CG 4.43Å; F104-L226 HydrophobicContact CE2-CD2 3.99Å; F104-L226 HydrophobicContact CZ-CD2 3.36Å; F104-L226 HydrophobicContact CZ-CG 4.04Å; F116-L226 HydrophobicContact CD2-CB 4.03Å; F116-L226 HydrophobicContact CE2-CB 4.02Å; I222-L226 PolarHBondContact O-N 3.45Å; M223-L226 HydrophobicContact CE-CD1 4.1Å; M223-L226 WeakPolarHBondContact O-CB 3.35Å; M223-L226 PolarHBondContact O-N 2.91Å; M223-L226 HydrophobicContact SD-CD1 3.65Å; L224-L226 VanDerWaalsContact C-N 3.3Å; L224-L226 PolarHBondContact O-N 3.28Å; L226-G230 PolarHBondContact O-N 3.15Å
227	G	94.6	Very high	94.4	Very high	0 Å²	0	3.8 Å²	3.8	0%	0	2%	0.02	C	C	.	.	H	α-helix	trans	-66	-45.1	175	0	0	0	0	0	111.7	M195 L224 K225 G230 M231	M195-G227 VanDerWaalsContact CG-C 3.46Å; L224-G227 PolarHBondContact O-N 2.96Å; K225-G227 PolarHBondContact O-N 3.22Å; G227-G230 PolarHBondContact O-N 3.46Å; G227-M231 VanDerWaalsContact O-CG 3.31Å; G227-M231 WeakPolarHBondContact O-CG 3.43Å; G227-M231 PolarHBondContact O-N 2.75Å
228	G	94.9	Very high	94.2	Very high	0 Å²	0	3.8 Å²	3.8	0%	0	2%	0.02	C	C	.	.	H	α-helix	trans	-63.2	-43.3	177.1	0	0	0	0	0	112.9	L224 K225 M231 L232	L224-G228 PolarHBondContact O-N 3.27Å; K225-G228 PolarHBondContact O-N 2.62Å; K225-G228 VanDerWaalsContact O-N 3.16Å; G228-M231 WeakPolarHBondContact O-CB 3.28Å; G228-M231 PolarHBondContact O-N 3.07Å; G228-L232 WeakPolarHBondContact O-CD1 3.36Å; G228-L232 VanDerWaalsContact O-CG 3.28Å; G228-L232 WeakPolarHBondContact O-CG 3.43Å; G228-L232 PolarHBondContact O-N 3.15Å
229	Y	95.5	Very high	94	Very high	0 Å²	0	7.2 Å²	7.2	0%	0	4%	0.036	C	C	.	.	H	α-helix	trans	-59.7	-46.1	173.5	178.1	-102.5	0	0	0	112.1	L57 L61 F104 F112 K225 M231 L232 R233	L57-Y229 HydrophobicContact CD2-CD2 4.18Å; L57-Y229 HydrophobicContact CD2-CE2 4.39Å; L61-Y229 HydrophobicContact CD1-CD2 3.58Å; L61-Y229 HydrophobicContact CD1-CG 3.93Å; F104-Y229 AromaticContact CD1-CD1 3.83Å; F104-Y229 HydrophobicContact CD1-CD1 3.83Å; F104-Y229 HydrophobicContact CD1-CD2 4.12Å; F104-Y229 HydrophobicContact CD1-CE1 4.18Å; F104-Y229 HydrophobicContact CD1-CE2 4.46Å; F104-Y229 AromaticContact CD1-CG 3.8Å; F104-Y229 HydrophobicContact CD1-CG 3.8Å; F104-Y229 HydrophobicContact CE1-CD1 4.23Å; F104-Y229 HydrophobicContact CE1-CG 4Å; F104-Y229 PolarHBondContact O-OH 3.31Å; F112-Y229 HydrophobicContact CD2-CD1 4.35Å; F112-Y229 AromaticContact CD2-CE1 4Å; F112-Y229 HydrophobicContact CD2-CE1 4Å; F112-Y229 AromaticContact CE2-CD1 3.55Å; F112-Y229 HydrophobicContact CE2-CD1 3.55Å; F112-Y229 AromaticContact CE2-CE1 3.66Å; F112-Y229 HydrophobicContact CE2-CE1 3.66Å; F112-Y229 HydrophobicContact CZ-CD1 4.07Å; F112-Y229 HydrophobicContact CZ-CE1 4.47Å; K225-Y229 WeakPolarHBondContact O-CB 3.41Å; K225-Y229 PolarHBondContact O-N 3.14Å; Y229-M231 PolarHBondContact O-N 3.41Å; Y229-L232 PolarHBondContact O-N 2.89Å; Y229-R233 HydrophobicContact CE1-CG 4.08Å; Y229-R233 HydrophobicContact CE2-CG 4.17Å; Y229-R233 WeakPolarHBondContact O-CG 3.17Å; Y229-R233 PolarHBondContact O-N 3.41Å; Y229-R233 VanDerWaalsContact O-N 3.09Å; Y229-R233 PolarHBondContact OH-NE 2.88Å; Y229-R233 PolarHBondContact OH-NH2 3.22Å
230	G	95.1	Very high	93.8	Very high	0 Å²	0	10.2 Å²	10.2	0%	0	5%	0.052	C	C	.	.	H	α-helix	trans	-59.8	-44.5	175.6	0	0	0	0	0	112.6	F191 L226 G227 L232 R233 V234	F191-G230 VanDerWaalsContact CE1-CA 3.49Å; L226-G230 PolarHBondContact O-N 3.15Å; G227-G230 PolarHBondContact O-N 3.46Å; G230-L232 PolarHBondContact O-N 3.38Å; G230-R233 PolarHBondContact O-N 3.12Å; G230-V234 WeakPolarHBondContact O-CB 3.39Å; G230-V234 WeakPolarHBondContact O-CG2 3.26Å; G230-V234 PolarHBondContact O-N 3.31Å
231	M	94.7	Very high	93.6	Very high	3 Å²	3	10.2 Å²	10.2	2%	0.015	5%	0.052	C	C	.	.	H	α-helix	trans	-56.8	-50.4	173.7	-70.5	-67.9	-96.3	0	0	111.1	L188 F191 L192 G227 G228 Y229 R233 V234 I235 L290	L188-M231 HydrophobicContact CB-SD 4.45Å; L188-M231 HydrophobicContact CD2-CE 3.85Å; L188-M231 HydrophobicContact CD2-SD 3.31Å; L188-M231 WeakPolarHBondContact CD2-SD 3.24Å; L188-M231 HydrophobicContact CG-SD 4.43Å; F191-M231 HydrophobicContact CB-CG 3.51Å; F191-M231 HydrophobicContact CB-SD 3.47Å; F191-M231 WeakPolarHBondContact CB-SD 3.31Å; F191-M231 HydrophobicContact CD2-CG 4.25Å; F191-M231 HydrophobicContact CD2-SD 3.83Å; F191-M231 HydrophobicContact CG-CG 4.11Å; F191-M231 HydrophobicContact CG-SD 4.08Å; L192-M231 HydrophobicContact CD2-CE 3.53Å; L192-M231 HydrophobicContact CG-CE 4.25Å; G227-M231 VanDerWaalsContact O-CG 3.31Å; G227-M231 WeakPolarHBondContact O-CG 3.43Å; G227-M231 PolarHBondContact O-N 2.75Å; G228-M231 WeakPolarHBondContact O-CB 3.28Å; G228-M231 PolarHBondContact O-N 3.07Å; Y229-M231 PolarHBondContact O-N 3.41Å; M231-R233 VanDerWaalsContact C-N 3.28Å; M231-R233 PolarHBondContact O-N 3.4Å; M231-V234 PolarHBondContact O-N 3.31Å; M231-V234 VanDerWaalsContact O-N 3.16Å; M231-I235 HydrophobicContact CB-CD1 3.99Å; M231-I235 HydrophobicContact CE-CD1 4.44Å; M231-I235 WeakPolarHBondContact O-CB 3.46Å; M231-I235 WeakPolarHBondContact O-CD1 3.43Å; M231-I235 WeakPolarHBondContact O-CG1 3.42Å; M231-I235 PolarHBondContact O-N 3.18Å; M231-L290 HydrophobicContact CE-CD2 3.98Å
232	L	94.2	Very high	93.6	Very high	17 Å²	17	10.2 Å²	10.2	9%	0.089	5%	0.052	C	C	.	.	H	α-helix	trans	-57.7	-39.9	-178.7	-73.8	158.6	0	0	0	113.2	L57 G228 Y229 G230 L289 L297 M304 W445	L57-L232 HydrophobicContact CD2-CD1 4.2Å; G228-L232 WeakPolarHBondContact O-CD1 3.36Å; G228-L232 VanDerWaalsContact O-CG 3.28Å; G228-L232 WeakPolarHBondContact O-CG 3.43Å; G228-L232 PolarHBondContact O-N 3.15Å; Y229-L232 PolarHBondContact O-N 2.89Å; G230-L232 PolarHBondContact O-N 3.38Å; L232-L289 HydrophobicContact CD1-CD2 4.21Å; L232-L289 HydrophobicContact CD2-CD2 3.24Å; L232-L289 HydrophobicContact CG-CD2 3.61Å; L232-L297 HydrophobicContact CD2-CD2 3.64Å; L232-M304 HydrophobicContact CD1-CE 3.57Å; L232-W445 HydrophobicContact CD1-CH2 3.3Å; L232-W445 HydrophobicContact CD1-CZ2 4.41Å; L232-W445 HydrophobicContact CD1-CZ3 3.79Å; L232-W445 HydrophobicContact CD2-CH2 3.31Å; L232-W445 HydrophobicContact CD2-CZ2 3.62Å; L232-W445 HydrophobicContact CD2-CZ3 4.48Å; L232-W445 HydrophobicContact CG-CH2 3.85Å
233	R	92.9	Very high	93.4	Very high	20 Å²	20	15.3 Å²	15.3	8%	0.075	8%	0.079	C	C	.	.	H	α-helix	trans	-75.2	-30.4	178.2	-67.5	-61.1	-166.2	-160.5	-2.4	114.2	D55 F170 Y229 G230 M231 S236 F237	D55-R233 IonicContact OD1-CZ 3.64Å; D55-R233 IonicContact OD1-NH2 3.88Å; D55-R233 PolarHBondContact OD1-NH2 3.46Å; D55-R233 IonicContact OD2-CZ 3.48Å; D55-R233 IonicContact OD2-NH1 3.06Å; D55-R233 PolarHBondContact OD2-NH1 3.35Å; D55-R233 IonicContact OD2-NH2 2.84Å; D55-R233 PolarHBondContact OD2-NH2 2.98Å; F170-R233 HydrophobicContact CD1-CB 3.99Å; F170-R233 HydrophobicContact CE1-CB 3.6Å; F170-R233 HydrophobicContact CE1-CG 4.33Å; F170-R233 HydrophobicContact CZ-CB 3.97Å; F170-R233 HydrophobicContact CZ-CG 4.31Å; Y229-R233 HydrophobicContact CE1-CG 4.08Å; Y229-R233 HydrophobicContact CE2-CG 4.17Å; Y229-R233 WeakPolarHBondContact O-CG 3.17Å; Y229-R233 PolarHBondContact O-N 3.41Å; Y229-R233 VanDerWaalsContact O-N 3.09Å; Y229-R233 PolarHBondContact OH-NE 2.88Å; Y229-R233 PolarHBondContact OH-NH2 3.22Å; G230-R233 PolarHBondContact O-N 3.12Å; M231-R233 VanDerWaalsContact C-N 3.28Å; M231-R233 PolarHBondContact O-N 3.4Å; R233-S236 PolarHBondContact O-OG 3.18Å; R233-F237 WeakPolarHBondContact O-CE1 3.36Å
234	V	93.4	Very high	93.3	Very high	0 Å²	0	20.7 Å²	20.7	0%	0	10%	0.102	C	C	.	.	H	α-helix	trans	-88	-35.6	-177.3	166.4	0	0	0	0	111.8	L109 L187 L188 F191 G230 M231 S236 F237 L238	L109-V234 HydrophobicContact CD1-CG2 4.14Å; L187-V234 HydrophobicContact CB-CG1 3.91Å; L187-V234 HydrophobicContact CD1-CG1 4.41Å; L188-V234 HydrophobicContact CD2-CG1 4.27Å; F191-V234 HydrophobicContact CE2-CB 3.97Å; F191-V234 HydrophobicContact CE2-CG1 4.4Å; F191-V234 HydrophobicContact CE2-CG2 3.59Å; F191-V234 HydrophobicContact CZ-CG2 3.99Å; G230-V234 WeakPolarHBondContact O-CB 3.39Å; G230-V234 WeakPolarHBondContact O-CG2 3.26Å; G230-V234 PolarHBondContact O-N 3.31Å; M231-V234 PolarHBondContact O-N 3.31Å; M231-V234 VanDerWaalsContact O-N 3.16Å; V234-S236 PolarHBondContact O-N 3.46Å; V234-F237 VanDerWaalsContact CA-CE1 3.5Å; V234-F237 HydrophobicContact CB-CE1 4.24Å; V234-F237 HydrophobicContact CB-CZ 4.01Å; V234-F237 HydrophobicContact CG1-CE1 4.47Å; V234-F237 HydrophobicContact CG1-CE2 4.19Å; V234-F237 HydrophobicContact CG1-CZ 3.79Å; V234-F237 HydrophobicContact CG2-CE1 4.13Å; V234-F237 HydrophobicContact CG2-CZ 3.9Å; V234-F237 PolarHBondContact O-N 3.27Å; V234-L238 HydrophobicContact CG1-CD1 3.42Å; V234-L238 VanDerWaalsContact CG1-CD1 3.42Å; V234-L238 HydrophobicContact CG1-CG 4.1Å; V234-L238 WeakPolarHBondContact O-CG 3.27Å; V234-L238 PolarHBondContact O-N 3.48Å
235	I	92.5	Very high	93.3	Very high	3 Å²	3	23.3 Å²	23.3	2%	0.015	11%	0.113	C	C	.	.	H	α-helix	trans	-61.3	-31.7	177.4	-77.1	172.9	0	0	0	111.7	L188 M231 F237 L238 Q239 L290 M292	L188-I235 HydrophobicContact CD2-CG1 4.15Å; M231-I235 HydrophobicContact CB-CD1 3.99Å; M231-I235 HydrophobicContact CE-CD1 4.44Å; M231-I235 WeakPolarHBondContact O-CB 3.46Å; M231-I235 WeakPolarHBondContact O-CD1 3.43Å; M231-I235 WeakPolarHBondContact O-CG1 3.42Å; M231-I235 PolarHBondContact O-N 3.18Å; I235-F237 PolarHBondContact O-N 2.98Å; I235-L238 CarbonylContact O-C 3.34Å; I235-L238 PolarHBondContact O-N 3.05Å; I235-L238 VanDerWaalsContact O-N 3.13Å; I235-Q239 WeakPolarHBondContact O-CG 3.19Å; I235-Q239 PolarHBondContact O-N 3.26Å; I235-L290 HydrophobicContact CD1-CD2 4.29Å; I235-M292 HydrophobicContact CB-SD 4.47Å; I235-M292 HydrophobicContact CG2-CE 3.36Å; I235-M292 HydrophobicContact CG2-SD 3.01Å; I235-M292 WeakPolarHBondContact CG2-SD 3.42Å
236	S	89.8	Confident	93.1	Very high	27 Å²	27	23.7 Å²	23.7	19%	0.189	12%	0.115	C	C	.	.	T	Hydrogen-bonded Turn	trans	-58.5	-32.5	-178.9	60.7	0	0	0	0	113.7	N174 R233 V234 Q239	N174-S236 WeakPolarHBondContact OD1-CB 2.85Å; N174-S236 PolarHBondContact OD1-OG 2.79Å; R233-S236 PolarHBondContact O-OG 3.18Å; V234-S236 PolarHBondContact O-N 3.46Å; S236-Q239 VanDerWaalsContact O-CG 3.31Å; S236-Q239 WeakPolarHBondContact O-CG 3.42Å; S236-Q239 PolarHBondContact O-NE2 3.16Å
237	F	90.9	Very high	93.1	Very high	0 Å²	0	29.3 Å²	29.3	0%	0	14%	0.14	C	C	.	.	T	Hydrogen-bonded Turn	trans	-104.3	-7.5	175.4	62.5	-101.4	0	0	0	113.8	L109 L161 M173 F178 L187 R233 V234 I235	L109-F237 HydrophobicContact CD1-CE1 3.63Å; L109-F237 HydrophobicContact CD1-CZ 3.49Å; L109-F237 VanDerWaalsContact CD1-CZ 3.49Å; L161-F237 HydrophobicContact CD1-CE2 4Å; L161-F237 HydrophobicContact CD1-CZ 4.26Å; M173-F237 HydrophobicContact CB-CD1 4.1Å; M173-F237 HydrophobicContact CB-CG 4.44Å; M173-F237 HydrophobicContact CE-CD2 4.43Å; M173-F237 HydrophobicContact CE-CE2 4.47Å; M173-F237 WeakPolarHBondContact O-CB 3.19Å; F178-F237 HydrophobicContact CD2-CB 4.48Å; F178-F237 AromaticContact CD2-CD2 3.91Å; F178-F237 HydrophobicContact CD2-CD2 3.91Å; F178-F237 HydrophobicContact CE2-CB 4.42Å; F178-F237 HydrophobicContact CE2-CD2 4.17Å; L187-F237 HydrophobicContact CD1-CE2 3.84Å; L187-F237 HydrophobicContact CD1-CZ 4.23Å; R233-F237 WeakPolarHBondContact O-CE1 3.36Å; V234-F237 VanDerWaalsContact CA-CE1 3.5Å; V234-F237 HydrophobicContact CB-CE1 4.24Å; V234-F237 HydrophobicContact CB-CZ 4.01Å; V234-F237 HydrophobicContact CG1-CE1 4.47Å; V234-F237 HydrophobicContact CG1-CE2 4.19Å; V234-F237 HydrophobicContact CG1-CZ 3.79Å; V234-F237 HydrophobicContact CG2-CE1 4.13Å; V234-F237 HydrophobicContact CG2-CZ 3.9Å; V234-F237 PolarHBondContact O-N 3.27Å; I235-F237 PolarHBondContact O-N 2.98Å
238	L	91.6	Very high	93.1	Very high	0 Å²	0	31.7 Å²	31.7	0%	0	15%	0.154	C	C	.	.			trans	-102.8	23.2	175.6	-63	-175.6	0	0	0	113.8	F178 L183 Y184 L187 L188 V234 I235 L240 M241 N242	F178-L238 HydrophobicContact CB-CD2 4.26Å; L183-L238 HydrophobicContact CD2-CD2 3.45Å; L183-L238 VanDerWaalsContact CD2-CD2 3.45Å; Y184-L238 HydrophobicContact CD2-CD1 4.35Å; L187-L238 HydrophobicContact CB-CD1 4.11Å; L187-L238 HydrophobicContact CD1-CD1 4.03Å; L187-L238 HydrophobicContact CD1-CD2 4.4Å; L188-L238 HydrophobicContact CG-CD1 4.34Å; V234-L238 HydrophobicContact CG1-CD1 3.42Å; V234-L238 VanDerWaalsContact CG1-CD1 3.42Å; V234-L238 HydrophobicContact CG1-CG 4.1Å; V234-L238 WeakPolarHBondContact O-CG 3.27Å; V234-L238 PolarHBondContact O-N 3.48Å; I235-L238 CarbonylContact O-C 3.34Å; I235-L238 PolarHBondContact O-N 3.05Å; I235-L238 VanDerWaalsContact O-N 3.13Å; L238-L240 PolarHBondContact O-N 3.21Å; L238-M241 PolarHBondContact O-N 2.68Å; L238-N242 WeakPolarHBondContact O-CB 3.46Å; L238-N242 PolarHBondContact O-N 3.03Å
239	Q	92	Very high	93.2	Very high	73 Å²	73	33.4 Å²	33.4	34%	0.341	16%	0.161	S	C	.	.	H	α-helix	trans	-55.9	-47.8	-171.2	-56.8	-174.9	5.8	0	0	113	M177 I235 S236 M241 N242 L243 M292	M177-Q239 HydrophobicContact CE-CB 4.33Å; M177-Q239 HydrophobicContact CE-CG 4.49Å; M177-Q239 HydrophobicContact SD-CB 4.13Å; M177-Q239 HydrophobicContact SD-CG 4.47Å; I235-Q239 WeakPolarHBondContact O-CG 3.19Å; I235-Q239 PolarHBondContact O-N 3.26Å; S236-Q239 VanDerWaalsContact O-CG 3.31Å; S236-Q239 WeakPolarHBondContact O-CG 3.42Å; S236-Q239 PolarHBondContact O-NE2 3.16Å; Q239-M241 VanDerWaalsContact C-N 3.35Å; Q239-M241 PolarHBondContact O-N 3.03Å; Q239-N242 PolarHBondContact O-N 3.44Å; Q239-L243 WeakPolarHBondContact O-CG 3.42Å; Q239-L243 PolarHBondContact O-N 2.92Å; Q239-M292 HydrophobicContact CG-CE 4.01Å
240	L	91.5	Very high	93.2	Very high	67 Å²	67	33.4 Å²	33.4	35%	0.351	16%	0.161	S	C	.	.	H	α-helix	trans	-60.7	-42.3	-177.5	-68.1	177.1	0	0	0	112.7	M177 N179 L238 K244	M177-L240 HydrophobicContact CB-CD1 3.78Å; M177-L240 HydrophobicContact CB-CG 4.45Å; M177-L240 HydrophobicContact CG-CD1 4.38Å; M177-L240 HydrophobicContact SD-CD1 4.48Å; M177-L240 HydrophobicContact SD-CG 4.18Å; N179-L240 WeakPolarHBondContact OD1-CB 3.3Å; N179-L240 WeakPolarHBondContact OD1-CD1 3.4Å; L238-L240 PolarHBondContact O-N 3.21Å; L240-K244 PolarHBondContact O-N 3.16Å
241	M	92.5	Very high	93.2	Very high	0 Å²	0	36.2 Å²	36.2	0%	0	18%	0.18	C	C	.	.	H	α-helix	trans	-75.5	-35.7	-179.7	-55.8	-54.8	-75.1	0	0	111.3	F178 N179 D181 Y184 L238 Q239 L243 K244 Y245	F178-M241 VanDerWaalsContact O-CG 3.28Å; F178-M241 WeakPolarHBondContact O-CG 3.43Å; N179-M241 VanDerWaalsContact CA-SD 3.57Å; D181-M241 HydrophobicContact CB-CE 4Å; D181-M241 WeakPolarHBondContact OD1-CE 3.37Å; Y184-M241 HydrophobicContact CD2-CB 3.43Å; Y184-M241 VanDerWaalsContact CD2-CB 3.43Å; Y184-M241 HydrophobicContact CE2-CB 4.15Å; Y184-M241 HydrophobicContact CG-CB 3.86Å; L238-M241 PolarHBondContact O-N 2.68Å; Q239-M241 VanDerWaalsContact C-N 3.35Å; Q239-M241 PolarHBondContact O-N 3.03Å; M241-L243 VanDerWaalsContact C-N 3.33Å; M241-L243 PolarHBondContact O-N 3.47Å; M241-K244 WeakPolarHBondContact O-CB 3.44Å; M241-K244 PolarHBondContact O-N 2.98Å; M241-K244 VanDerWaalsContact O-N 3.17Å; M241-K244 HydrophobicContact SD-CD 4.32Å; M241-Y245 HydrophobicContact CE-CE2 4.14Å; M241-Y245 WeakPolarHBondContact O-CD2 3.42Å; M241-Y245 PolarHBondContact O-N 2.62Å; M241-Y245 VanDerWaalsContact O-N 3.09Å
242	N	92.8	Very high	93.3	Very high	0 Å²	0	38 Å²	38	0%	0	19%	0.19	C	C	.	.	H	α-helix	trans	-63.3	-40.9	175.8	-164.6	43.6	0	0	0	111.9	Y184 L238 Q239 K244 Y245 S246 L290 M292	Y184-N242 VanDerWaalsContact CE2-CA 3.45Å; Y184-N242 HydrophobicContact CE2-CB 3.94Å; Y184-N242 PolarHBondContact OH-OD1 3.37Å; L238-N242 WeakPolarHBondContact O-CB 3.46Å; L238-N242 PolarHBondContact O-N 3.03Å; Q239-N242 PolarHBondContact O-N 3.44Å; N242-K244 VanDerWaalsContact C-N 3.26Å; N242-K244 PolarHBondContact O-N 3.41Å; N242-Y245 PolarHBondContact O-N 3.35Å; N242-S246 WeakPolarHBondContact O-CA 3.45Å; N242-S246 WeakPolarHBondContact O-CB 3.24Å; N242-S246 PolarHBondContact O-N 3.44Å; N242-S246 PolarHBondContact O-OG 3.4Å; N242-L290 WeakPolarHBondContact OD1-CD2 3.27Å; N242-M292 WeakPolarHBondContact ND2-CG 3.35Å; N242-M292 PolarHBondContact ND2-SD 3.07Å; N242-M292 VanDerWaalsContact ND2-SD 3.38Å
243	L	91.7	Very high	93.4	Very high	108 Å²	108	37.4 Å²	37.4	57%	0.565	19%	0.187	S	C	*	.	H	α-helix	trans	-57.5	-40.5	174.2	-70	171.9	0	0	0	111.8	Q239 M241 S246	Q239-L243 WeakPolarHBondContact O-CG 3.42Å; Q239-L243 PolarHBondContact O-N 2.92Å; M241-L243 VanDerWaalsContact C-N 3.33Å; M241-L243 PolarHBondContact O-N 3.47Å; L243-S246 PolarHBondContact O-OG 3.29Å
244	K	93.8	Very high	93.5	Very high	116 Å²	116	36.6 Å²	36.6	50%	0.504	18%	0.184	S	C	.	.	H	α-helix	trans	-65.9	-44.2	177.8	-67.8	178.6	-178.5	177	0	113.5	L240 M241 N242 F247	L240-K244 PolarHBondContact O-N 3.16Å; M241-K244 WeakPolarHBondContact O-CB 3.44Å; M241-K244 PolarHBondContact O-N 2.98Å; M241-K244 VanDerWaalsContact O-N 3.17Å; M241-K244 HydrophobicContact SD-CD 4.32Å; N242-K244 VanDerWaalsContact C-N 3.26Å; N242-K244 PolarHBondContact O-N 3.41Å; K244-F247 VanDerWaalsContact O-CD1 3.23Å; K244-F247 WeakPolarHBondContact O-CD1 3.37Å; K244-F247 WeakPolarHBondContact O-CE1 3.35Å
245	Y	94.1	Very high	93.6	Very high	56 Å²	56	39.8 Å²	39.8	22%	0.22	20%	0.203	C	C	.	.	H	α-helix	trans	-100.5	-7.6	-172.1	-67.6	-67.7	0	0	0	115	D181 Y184 F185 M241 N242 F247 V248	D181-Y245 VanDerWaalsContact OD1-CE2 3.27Å; D181-Y245 WeakPolarHBondContact OD1-CE2 3.39Å; D181-Y245 PolarHBondContact OD1-OH 3.43Å; Y184-Y245 AromaticContact CD1-CD2 3.53Å; Y184-Y245 HydrophobicContact CD1-CD2 3.53Å; Y184-Y245 HydrophobicContact CD1-CE2 4.11Å; Y184-Y245 HydrophobicContact CD1-CG 4.18Å; Y184-Y245 AromaticContact CE1-CD2 3.51Å; Y184-Y245 HydrophobicContact CE1-CD2 3.51Å; Y184-Y245 HydrophobicContact CE1-CE2 4.48Å; Y184-Y245 AromaticContact CE1-CG 3.73Å; Y184-Y245 HydrophobicContact CE1-CG 3.73Å; Y184-Y245 HydrophobicContact CG-CD2 4.12Å; F185-Y245 HydrophobicContact CE2-CE1 4.12Å; F185-Y245 HydrophobicContact CE2-CE2 4.18Å; F185-Y245 AromaticContact CE2-CZ 3.88Å; F185-Y245 AromaticContact CZ-CD1 3.99Å; F185-Y245 HydrophobicContact CZ-CD1 3.99Å; F185-Y245 AromaticContact CZ-CE1 3.81Å; F185-Y245 HydrophobicContact CZ-CE1 3.81Å; F185-Y245 HydrophobicContact CZ-CE2 4.38Å; F185-Y245 HydrophobicContact CZ-CG 4.36Å; M241-Y245 HydrophobicContact CE-CE2 4.14Å; M241-Y245 WeakPolarHBondContact O-CD2 3.42Å; M241-Y245 PolarHBondContact O-N 2.62Å; M241-Y245 VanDerWaalsContact O-N 3.09Å; N242-Y245 PolarHBondContact O-N 3.35Å; Y245-F247 PolarHBondContact O-N 3.07Å; Y245-F247 VanDerWaalsContact O-N 3.11Å; Y245-V248 PolarHBondContact O-N 3.11Å; Y245-V248 VanDerWaalsContact O-N 3.11Å
246	S	93	Very high	93.8	Very high	8 Å²	8	39.7 Å²	39.7	6%	0.056	20%	0.203	C	C	.	.	H	α-helix	trans	-49.1	-41.6	-176.8	55.7	0	0	0	0	113.3	N242 L243 V248 W249 I250	N242-S246 WeakPolarHBondContact O-CA 3.45Å; N242-S246 WeakPolarHBondContact O-CB 3.24Å; N242-S246 PolarHBondContact O-N 3.44Å; N242-S246 PolarHBondContact O-OG 3.4Å; L243-S246 PolarHBondContact O-OG 3.29Å; S246-V248 VanDerWaalsContact C-N 3.29Å; S246-V248 PolarHBondContact O-N 3.11Å; S246-W249 PolarHBondContact O-N 3.38Å; S246-I250 WeakPolarHBondContact O-CB 3.21Å; S246-I250 VanDerWaalsContact O-CG1 3.24Å; S246-I250 WeakPolarHBondContact O-CG1 3.27Å; S246-I250 PolarHBondContact O-N 2.94Å
247	F	93.8	Very high	94.1	Very high	117 Å²	117	38.6 Å²	38.6	51%	0.513	20%	0.196	S	C	.	.	H	α-helix	trans	-58.1	-38.3	-176.9	74.7	-90.5	0	0	0	113.2	K244 Y245 S251 W376	K244-F247 VanDerWaalsContact O-CD1 3.23Å; K244-F247 WeakPolarHBondContact O-CD1 3.37Å; K244-F247 WeakPolarHBondContact O-CE1 3.35Å; Y245-F247 PolarHBondContact O-N 3.07Å; Y245-F247 VanDerWaalsContact O-N 3.11Å; F247-S251 WeakPolarHBondContact O-CB 3.25Å; F247-S251 PolarHBondContact O-N 3.43Å; F247-S251 VanDerWaalsContact O-N 3.11Å; F247-S251 PolarHBondContact O-OG 3.49Å; F247-W376 HydrophobicContact CB-CH2 4.07Å; F247-W376 HydrophobicContact CB-CZ2 3.75Å
248	V	95.5	Very high	94.4	Very high	50 Å²	50	39.4 Å²	39.4	30%	0.303	20%	0.201	S	C	.	.	H	α-helix	trans	-64	-52.9	-179	178.8	0	0	0	0	109.2	Y245 S246 S251 I252	Y245-V248 PolarHBondContact O-N 3.11Å; Y245-V248 VanDerWaalsContact O-N 3.11Å; S246-V248 VanDerWaalsContact C-N 3.29Å; S246-V248 PolarHBondContact O-N 3.11Å; V248-S251 PolarHBondContact O-N 2.85Å; V248-S251 PolarHBondContact O-OG 3.44Å; V248-I252 HydrophobicContact CG1-CD1 3.88Å; V248-I252 WeakPolarHBondContact O-CG1 3.42Å; V248-I252 PolarHBondContact O-N 2.97Å; V248-I252 VanDerWaalsContact O-N 3.14Å
249	W	95	Very high	94.6	Very high	37 Å²	37	43.1 Å²	43.1	14%	0.14	22%	0.22	C	C	.	.	H	α-helix	trans	-70.9	-38.5	-174.1	-59.1	127.6	0	0	0	113.1	Y184 F185 L192 M197 S246 S251 I252 S253 L290	Y184-W249 AromaticContact CE1-NE1 3.73Å; Y184-W249 AromaticContact CZ-NE1 3.9Å; Y184-W249 VanDerWaalsContact OH-CD1 3.32Å; Y184-W249 PolarHBondContact OH-NE1 2.92Å; F185-W249 HydrophobicContact CD1-CZ2 4.17Å; F185-W249 AromaticContact CE1-CZ2 3.95Å; F185-W249 HydrophobicContact CE1-CZ2 3.95Å; L192-W249 HydrophobicContact CD1-CD2 3.92Å; L192-W249 HydrophobicContact CD1-CE3 3.95Å; L192-W249 HydrophobicContact CD1-CH2 3.59Å; L192-W249 HydrophobicContact CD1-CZ2 3.61Å; L192-W249 HydrophobicContact CD1-CZ3 3.77Å; M197-W249 HydrophobicContact CE-CB 3.88Å; M197-W249 HydrophobicContact CE-CD2 3.77Å; M197-W249 HydrophobicContact CE-CE3 3.14Å; M197-W249 HydrophobicContact CE-CG 4.11Å; M197-W249 HydrophobicContact CE-CZ3 3.84Å; M197-W249 HydrophobicContact SD-CE3 3.45Å; M197-W249 HydrophobicContact SD-CZ3 3.6Å; S246-W249 PolarHBondContact O-N 3.38Å; W249-S251 VanDerWaalsContact C-N 3.32Å; W249-S251 PolarHBondContact O-N 3.48Å; W249-I252 HydrophobicContact CE3-CD1 4.07Å; W249-I252 HydrophobicContact CZ3-CD1 4.39Å; W249-I252 PolarHBondContact O-N 3.19Å; W249-S253 WeakPolarHBondContact O-CB 3.37Å; W249-S253 PolarHBondContact O-N 3.46Å; W249-S253 PolarHBondContact O-OG 2.87Å; W249-L290 HydrophobicContact CB-CD1 3.35Å; W249-L290 HydrophobicContact CG-CD1 4.24Å
250	I	95.7	Very high	94.9	Very high	0 Å²	0	39.7 Å²	39.7	0%	0	20%	0.204	C	C	.	.	H	α-helix	trans	-61.4	-42.7	174.4	-66.7	166.5	0	0	0	110.2	S246 S253 L254 L290 T291 W376	S246-I250 WeakPolarHBondContact O-CB 3.21Å; S246-I250 VanDerWaalsContact O-CG1 3.24Å; S246-I250 WeakPolarHBondContact O-CG1 3.27Å; S246-I250 PolarHBondContact O-N 2.94Å; I250-S253 PolarHBondContact O-N 3.3Å; I250-S253 PolarHBondContact O-OG 3.33Å; I250-S253 VanDerWaalsContact O-OG 3.1Å; I250-L254 HydrophobicContact CG2-CD1 3.78Å; I250-L254 HydrophobicContact CG2-CG 4.29Å; I250-L254 WeakPolarHBondContact O-CB 3.33Å; I250-L254 WeakPolarHBondContact O-CG 3.1Å; I250-L254 PolarHBondContact O-N 3.33Å; I250-L290 HydrophobicContact CD1-CB 4.22Å; I250-L290 HydrophobicContact CG1-CB 3.89Å; I250-T291 HydrophobicContact CD1-CG2 4.18Å; I250-W376 HydrophobicContact CB-CZ3 4.48Å; I250-W376 HydrophobicContact CD1-CD2 3.98Å; I250-W376 HydrophobicContact CD1-CE3 4.32Å; I250-W376 HydrophobicContact CD1-CG 4.43Å; I250-W376 HydrophobicContact CD1-CH2 4.47Å; I250-W376 HydrophobicContact CD1-CZ2 4.11Å; I250-W376 HydrophobicContact CG2-CE3 4.06Å; I250-W376 HydrophobicContact CG2-CH2 4.32Å; I250-W376 HydrophobicContact CG2-CZ3 3.82Å
251	S	95.5	Very high	95.1	Very high	58 Å²	58	36.6 Å²	36.6	41%	0.406	19%	0.188	S	C	.	.	H	α-helix	trans	-64.1	-43.9	179.4	72.6	0	0	0	0	112.2	F247 V248 W249 S253 V255	F247-S251 WeakPolarHBondContact O-CB 3.25Å; F247-S251 PolarHBondContact O-N 3.43Å; F247-S251 VanDerWaalsContact O-N 3.11Å; F247-S251 PolarHBondContact O-OG 3.49Å; V248-S251 PolarHBondContact O-N 2.85Å; V248-S251 PolarHBondContact O-OG 3.44Å; W249-S251 VanDerWaalsContact C-N 3.32Å; W249-S251 PolarHBondContact O-N 3.48Å; S251-S253 VanDerWaalsContact C-N 3.34Å; S251-S253 PolarHBondContact O-N 3.33Å; S251-V255 WeakPolarHBondContact O-CB 3.47Å; S251-V255 VanDerWaalsContact O-CG2 3.31Å; S251-V255 WeakPolarHBondContact O-CG2 3.38Å; S251-V255 PolarHBondContact O-N 3.43Å; S251-V255 VanDerWaalsContact O-N 3.11Å
252	I	96.7	Very high	95.3	Very high	42 Å²	42	39.8 Å²	39.8	22%	0.215	21%	0.205	C	C	.	.	H	α-helix	trans	-64.4	-40.1	178	-65.1	165.3	0	0	0	110.8	M197 F198 V248 W249 G256	M197-I252 HydrophobicContact CG-CG2 3.78Å; M197-I252 HydrophobicContact SD-CB 4.38Å; M197-I252 HydrophobicContact SD-CG2 3.81Å; F198-I252 HydrophobicContact CB-CG2 4.21Å; V248-I252 HydrophobicContact CG1-CD1 3.88Å; V248-I252 WeakPolarHBondContact O-CG1 3.42Å; V248-I252 PolarHBondContact O-N 2.97Å; V248-I252 VanDerWaalsContact O-N 3.14Å; W249-I252 HydrophobicContact CE3-CD1 4.07Å; W249-I252 HydrophobicContact CZ3-CD1 4.39Å; W249-I252 PolarHBondContact O-N 3.19Å; I252-G256 WeakPolarHBondContact O-CA 3.38Å; I252-G256 PolarHBondContact O-N 3.11Å
253	S	95.9	Very high	95.5	Very high	4 Å²	4	41.7 Å²	41.7	3%	0.028	22%	0.216	C	C	.	.	H	α-helix	trans	-72.2	-42.1	-177.2	76.7	0	0	0	0	112.9	W249 I250 S251 G257 G283 S287	W249-S253 WeakPolarHBondContact O-CB 3.37Å; W249-S253 PolarHBondContact O-N 3.46Å; W249-S253 PolarHBondContact O-OG 2.87Å; I250-S253 PolarHBondContact O-N 3.3Å; I250-S253 PolarHBondContact O-OG 3.33Å; I250-S253 VanDerWaalsContact O-OG 3.1Å; S251-S253 VanDerWaalsContact C-N 3.34Å; S251-S253 PolarHBondContact O-N 3.33Å; S253-G257 PolarHBondContact O-N 3.14Å; S253-G283 PolarHBondContact OG-O 3.03Å; S253-S287 WeakPolarHBondContact OG-CB 3.01Å
254	L	95.8	Very high	95.7	Very high	3 Å²	3	36.5 Å²	36.5	2%	0.016	19%	0.189	C	C	.	.	H	α-helix	trans	-68.9	-50.8	179	-69.3	176.3	0	0	0	111.6	I250 G256 G257 V258 I373 L383 L384 L387	I250-L254 HydrophobicContact CG2-CD1 3.78Å; I250-L254 HydrophobicContact CG2-CG 4.29Å; I250-L254 WeakPolarHBondContact O-CB 3.33Å; I250-L254 WeakPolarHBondContact O-CG 3.1Å; I250-L254 PolarHBondContact O-N 3.33Å; L254-G256 VanDerWaalsContact C-N 3.32Å; L254-G256 PolarHBondContact O-N 3.11Å; L254-G257 PolarHBondContact O-N 2.9Å; L254-V258 WeakPolarHBondContact O-CG2 3.15Å; L254-V258 PolarHBondContact O-N 3.3Å; L254-I373 HydrophobicContact CD1-CG2 3.99Å; L254-I373 HydrophobicContact CD2-CD1 4.48Å; L254-I373 HydrophobicContact CD2-CG2 4.45Å; L254-L383 HydrophobicContact CB-CB 4.21Å; L254-L383 HydrophobicContact CB-CD1 3.77Å; L254-L383 HydrophobicContact CD1-CD1 4.39Å; L254-L384 HydrophobicContact CD2-CD2 3.72Å; L254-L384 HydrophobicContact CD2-CG 4.47Å; L254-L387 HydrophobicContact CD2-CD1 3.81Å
255	V	96.6	Very high	95.8	Very high	67 Å²	67	33.6 Å²	33.6	41%	0.406	18%	0.179	S	C	.	.	H	α-helix	trans	-62.5	-44.6	177.7	175.1	0	0	0	0	110.1	S251 G257 V258 L259 L383	S251-V255 WeakPolarHBondContact O-CB 3.47Å; S251-V255 VanDerWaalsContact O-CG2 3.31Å; S251-V255 WeakPolarHBondContact O-CG2 3.38Å; S251-V255 PolarHBondContact O-N 3.43Å; S251-V255 VanDerWaalsContact O-N 3.11Å; V255-G257 PolarHBondContact O-N 2.76Å; V255-V258 PolarHBondContact O-N 3.08Å; V255-L259 HydrophobicContact CG1-CD1 4.15Å; V255-L259 WeakPolarHBondContact O-CG 3.48Å; V255-L259 PolarHBondContact O-N 3.17Å; V255-L383 HydrophobicContact CG2-CD1 3.95Å; V255-L383 HydrophobicContact CG2-CD2 4.38Å
256	G	95.9	Very high	95.9	Very high	1 Å²	1	40.1 Å²	40.1	1%	0.01	20%	0.203	C	C	.	.	H	α-helix	trans	-62	-41	178.3	0	0	0	0	0	113.9	F198 I252 L254 V258 L259 V260	F198-G256 VanDerWaalsContact CB-CA 3.49Å; F198-G256 VanDerWaalsContact CD2-CA 3.42Å; F198-G256 WeakPolarHBondContact CD2-O 3.38Å; I252-G256 WeakPolarHBondContact O-CA 3.38Å; I252-G256 PolarHBondContact O-N 3.11Å; L254-G256 VanDerWaalsContact C-N 3.32Å; L254-G256 PolarHBondContact O-N 3.11Å; G256-V258 VanDerWaalsContact C-N 3.33Å; G256-V258 PolarHBondContact O-N 3.46Å; G256-L259 PolarHBondContact O-N 3.21Å; G256-V260 WeakPolarHBondContact O-CB 3.3Å; G256-V260 VanDerWaalsContact O-CG2 3.28Å; G256-V260 WeakPolarHBondContact O-CG2 3.44Å; G256-V260 PolarHBondContact O-N 3.23Å
257	G	95.7	Very high	96	Very high	3 Å²	3	41.7 Å²	41.7	3%	0.031	21%	0.209	C	C	.	.	H	α-helix	trans	-61.1	-41	175.4	0	0	0	0	0	112.1	S253 L254 V255 V260 S261	S253-G257 PolarHBondContact O-N 3.14Å; L254-G257 PolarHBondContact O-N 2.9Å; V255-G257 PolarHBondContact O-N 2.76Å; G257-V260 PolarHBondContact O-N 3.06Å; G257-S261 WeakPolarHBondContact O-CB 3.35Å; G257-S261 PolarHBondContact O-N 2.97Å; G257-S261 PolarHBondContact O-OG 3.36Å
258	V	96.8	Very high	96.1	Very high	18 Å²	18	39.6 Å²	39.6	11%	0.109	21%	0.206	C	C	.	.	H	α-helix	trans	-63.2	-47.7	176.2	176.5	0	0	0	0	109.8	L254 V255 G256 V260 S261 L262 L383 F386 L387 F390	L254-V258 WeakPolarHBondContact O-CG2 3.15Å; L254-V258 PolarHBondContact O-N 3.3Å; V255-V258 PolarHBondContact O-N 3.08Å; G256-V258 VanDerWaalsContact C-N 3.33Å; G256-V258 PolarHBondContact O-N 3.46Å; V258-V260 VanDerWaalsContact C-N 3.34Å; V258-V260 PolarHBondContact O-N 3.38Å; V258-S261 PolarHBondContact O-N 3.32Å; V258-S261 PolarHBondContact O-OG 3.06Å; V258-L262 PolarHBondContact O-N 3.14Å; V258-L262 VanDerWaalsContact O-N 3.08Å; V258-L383 HydrophobicContact CG2-CD2 4.32Å; V258-F386 HydrophobicContact CG1-CB 4.25Å; V258-F386 HydrophobicContact CG2-CB 4.11Å; V258-L387 HydrophobicContact CG2-CD1 4.43Å; V258-L387 HydrophobicContact CG2-CD2 3.9Å; V258-L387 HydrophobicContact CG2-CG 3.66Å; V258-L387 VanDerWaalsContact N-CD2 3.28Å; V258-F390 HydrophobicContact CG1-CD2 4.36Å; V258-F390 HydrophobicContact CG1-CE2 4.24Å
259	L	96.9	Very high	96.1	Very high	78 Å²	78	39.7 Å²	39.7	41%	0.408	21%	0.205	S	C	.	.	H	α-helix	trans	-61.2	-42.1	179	-67.5	174.4	0	0	0	112.3	F198 V255 G256 L262 V263	F198-L259 HydrophobicContact CE1-CD1 3.81Å; F198-L259 HydrophobicContact CE2-CB 3.97Å; F198-L259 HydrophobicContact CE2-CD1 4.29Å; F198-L259 HydrophobicContact CZ-CB 3.99Å; F198-L259 HydrophobicContact CZ-CD1 3.49Å; F198-L259 VanDerWaalsContact CZ-CD1 3.49Å; F198-L259 HydrophobicContact CZ-CG 4.4Å; V255-L259 HydrophobicContact CG1-CD1 4.15Å; V255-L259 WeakPolarHBondContact O-CG 3.48Å; V255-L259 PolarHBondContact O-N 3.17Å; G256-L259 PolarHBondContact O-N 3.21Å; L259-L262 PolarHBondContact O-N 3.34Å; L259-V263 WeakPolarHBondContact O-CG2 3.48Å; L259-V263 PolarHBondContact O-N 3.18Å
260	V	97.1	Very high	96.1	Very high	1 Å²	1	38.1 Å²	38.1	1%	0.006	20%	0.199	C	C	.	.	H	α-helix	trans	-64.9	-40.4	176.3	172.2	0	0	0	0	111.2	F198 G256 G257 V258 L262 V263 C264 Y276 V279	F198-V260 HydrophobicContact CD2-CG2 3.75Å; F198-V260 HydrophobicContact CE2-CG2 3.99Å; G256-V260 WeakPolarHBondContact O-CB 3.3Å; G256-V260 VanDerWaalsContact O-CG2 3.28Å; G256-V260 WeakPolarHBondContact O-CG2 3.44Å; G256-V260 PolarHBondContact O-N 3.23Å; G257-V260 PolarHBondContact O-N 3.06Å; V258-V260 VanDerWaalsContact C-N 3.34Å; V258-V260 PolarHBondContact O-N 3.38Å; V260-L262 VanDerWaalsContact C-N 3.29Å; V260-L262 PolarHBondContact O-N 3.41Å; V260-V263 CarbonylContact O-C 3.53Å; V260-V263 WeakPolarHBondContact O-CA 3.41Å; V260-V263 WeakPolarHBondContact O-CB 3.25Å; V260-V263 PolarHBondContact O-N 3.3Å; V260-C264 PolarHBondContact O-N 3.42Å; V260-C264 PolarHBondContact O-SG 3.14Å; V260-Y276 HydrophobicContact CG1-CD1 3.94Å; V260-Y276 HydrophobicContact CG1-CG 4.4Å; V260-Y276 WeakPolarHBondContact CG1-O 3.4Å; V260-V279 HydrophobicContact CG1-CB 4.12Å; V260-V279 HydrophobicContact CG1-CG1 4.2Å; V260-V279 HydrophobicContact CG2-CG1 4.03Å
261	S	96.6	Very high	96.1	Very high	1 Å²	1	38.3 Å²	38.3	1%	0.007	20%	0.2	C	C	.	.	H	α-helix	trans	-62	-35.6	176.9	75	0	0	0	0	112.7	G257 V258 C264 F390	G257-S261 WeakPolarHBondContact O-CB 3.35Å; G257-S261 PolarHBondContact O-N 2.97Å; G257-S261 PolarHBondContact O-OG 3.36Å; V258-S261 PolarHBondContact O-N 3.32Å; V258-S261 PolarHBondContact O-OG 3.06Å; S261-C264 WeakPolarHBondContact O-CB 3.43Å; S261-C264 PolarHBondContact O-N 2.89Å; S261-F390 WeakPolarHBondContact OG-CB 3.41Å; S261-F390 WeakPolarHBondContact OG-CD2 3.5Å
262	L	96.6	Very high	96.1	Very high	67 Å²	67	35.9 Å²	35.9	35%	0.351	18%	0.184	S	C	.	.	H	α-helix	trans	-68.8	-34.9	171.3	-68.7	172.6	0	0	0	112.4	V258 L259 V260 F390	V258-L262 PolarHBondContact O-N 3.14Å; V258-L262 VanDerWaalsContact O-N 3.08Å; L259-L262 PolarHBondContact O-N 3.34Å; V260-L262 VanDerWaalsContact C-N 3.29Å; V260-L262 PolarHBondContact O-N 3.41Å; L262-F390 HydrophobicContact CD2-CD1 4.18Å; L262-F390 HydrophobicContact CD2-CD2 4.38Å; L262-F390 HydrophobicContact CD2-CE1 3.67Å; L262-F390 HydrophobicContact CD2-CE2 3.91Å; L262-F390 HydrophobicContact CD2-CZ 3.54Å; L262-F390 HydrophobicContact CG-CE2 4.34Å; L262-F390 HydrophobicContact CG-CZ 4.44Å
263	V	97	Very high	96.2	Very high	40 Å²	40	34 Å²	34	24%	0.242	17%	0.174	C	C	.	.	H	α-helix	trans	-63.4	-42.8	172.7	171.5	0	0	0	0	110.2	L259 V260 L265 R266 Q267 Y276	L259-V263 WeakPolarHBondContact O-CG2 3.48Å; L259-V263 PolarHBondContact O-N 3.18Å; V260-V263 CarbonylContact O-C 3.53Å; V260-V263 WeakPolarHBondContact O-CA 3.41Å; V260-V263 WeakPolarHBondContact O-CB 3.25Å; V260-V263 PolarHBondContact O-N 3.3Å; V263-L265 VanDerWaalsContact C-N 3.27Å; V263-L265 PolarHBondContact O-N 3.44Å; V263-R266 PolarHBondContact O-N 3.45Å; V263-Q267 HydrophobicContact CG1-CG 4.33Å; V263-Q267 VanDerWaalsContact CG1-NE2 3.25Å; V263-Q267 WeakPolarHBondContact O-CG 3.24Å; V263-Q267 PolarHBondContact O-N 3.04Å; V263-Y276 HydrophobicContact CG1-CD1 4.41Å; V263-Y276 HydrophobicContact CG1-CD2 4.42Å; V263-Y276 HydrophobicContact CG1-CE1 4.3Å; V263-Y276 HydrophobicContact CG1-CE2 4.34Å; V263-Y276 HydrophobicContact CG1-CG 4.47Å
264	C	96.2	Very high	96.2	Very high	0 Å²	0	33.8 Å²	33.8	0%	0	17%	0.173	C	C	.	.	H	α-helix	trans	-53	-42.2	178.3	-65.1	0	0	0	0	113	V260 S261 R266 Q267 L273 Y276 Y394	V260-C264 PolarHBondContact O-N 3.42Å; V260-C264 PolarHBondContact O-SG 3.14Å; S261-C264 WeakPolarHBondContact O-CB 3.43Å; S261-C264 PolarHBondContact O-N 2.89Å; C264-R266 PolarHBondContact O-N 3.39Å; C264-Q267 PolarHBondContact O-N 3Å; C264-Q267 VanDerWaalsContact O-N 3.13Å; C264-L273 HydrophobicContact CB-CG 4.48Å; C264-Y276 WeakPolarHBondContact SG-CB 3.39Å; C264-Y394 HydrophobicContact CB-CD1 3.92Å; C264-Y394 HydrophobicContact CB-CG 3.88Å
265	L	95.7	Very high	96.3	Very high	54 Å²	54	33.6 Å²	33.6	28%	0.283	17%	0.172	S	C	.	.	H	α-helix	trans	-63.6	-21.9	-179.7	-69.5	172.2	0	0	0	113.7	V263 F390 A393	V263-L265 VanDerWaalsContact C-N 3.27Å; V263-L265 PolarHBondContact O-N 3.44Å; L265-F390 HydrophobicContact CD1-CD1 4Å; L265-F390 HydrophobicContact CD1-CE1 4.38Å; L265-A393 HydrophobicContact CD2-CB 4.09Å
266	R	96	Very high	96.3	Very high	193 Å²	193	32.3 Å²	32.3	73%	0.728	16%	0.16	S	C	*	.	H	α-helix	trans	-98.6	-6.4	178.4	-63.5	-171.3	-66.3	173.4	-0	113.3	V263 C264 T268	V263-R266 PolarHBondContact O-N 3.45Å; C264-R266 PolarHBondContact O-N 3.39Å; R266-T268 PolarHBondContact O-N 3.11Å
267	Q	95.4	Very high	96.3	Very high	41 Å²	41	32.3 Å²	32.3	19%	0.192	16%	0.16	C	C	.	.			trans	-73.1	130.1	-177.9	-68.8	-60.2	-18.7	0	0	111.1	V263 C264 L273 Y276	V263-Q267 HydrophobicContact CG1-CG 4.33Å; V263-Q267 VanDerWaalsContact CG1-NE2 3.25Å; V263-Q267 WeakPolarHBondContact O-CG 3.24Å; V263-Q267 PolarHBondContact O-N 3.04Å; C264-Q267 PolarHBondContact O-N 3Å; C264-Q267 VanDerWaalsContact O-N 3.13Å; Q267-L273 HydrophobicContact CB-CB 4.04Å; Q267-L273 HydrophobicContact CB-CG 4.45Å; Q267-Y276 HydrophobicContact CG-CD2 3.84Å; Q267-Y276 HydrophobicContact CG-CE2 4.12Å
268	T	95.5	Very high	96.3	Very high	74 Å²	74	32.2 Å²	32.2	45%	0.454	16%	0.159	S	C	.	.			trans	-92.3	-17.9	175.6	52.9	0	0	0	0	112.8	R266 M330	R266-T268 PolarHBondContact O-N 3.11Å; T268-M330 VanDerWaalsContact O-CB 3.25Å; T268-M330 WeakPolarHBondContact O-CB 3.45Å; T268-M330 WeakPolarHBondContact O-CG 3.48Å; T268-M330 PolarHBondContact O-N 3.47Å
269	D	95.8	Very high	96.3	Very high	52 Å²	52	31.5 Å²	31.5	28%	0.278	16%	0.155	S	C	.	.	B	Isolated β-bridge	trans	-94.7	126.9	-179	-74.6	-28	0	0	0	111.6	K271 A272 L273	D269-K271 PolarHBondContact O-N 2.86Å; D269-A272 HydrophobicContact CB-CB 3.76Å; D269-A272 PolarHBondContact O-N 3.28Å; D269-L273 WeakPolarHBondContact O-CB 3.46Å; D269-L273 PolarHBondContact O-N 3.28Å
270	L	95.1	Very high	96.2	Very high	3 Å²	3	28 Å²	28	2%	0.016	14%	0.137	C	C	.	.	H	α-helix	trans	-56.5	-50.8	-179.3	-84.9	161.2	0	0	0	112.6	L273 I274 R328 M330 N333 W347	L270-L273 PolarHBondContact O-N 2.98Å; L270-I274 WeakPolarHBondContact O-CG1 3.37Å; L270-I274 PolarHBondContact O-N 3.11Å; L270-I274 VanDerWaalsContact O-N 3.14Å; L270-R328 WeakPolarHBondContact CB-O 3.47Å; L270-R328 PolarHBondContact N-O 3.13Å; L270-M330 HydrophobicContact CB-SD 4.46Å; L270-M330 HydrophobicContact CD1-SD 4.33Å; L270-M330 HydrophobicContact CD2-CE 4.43Å; L270-M330 HydrophobicContact CD2-CG 4.41Å; L270-M330 HydrophobicContact CD2-SD 3.08Å; L270-M330 WeakPolarHBondContact CD2-SD 3.13Å; L270-M330 HydrophobicContact CG-CG 4.12Å; L270-M330 HydrophobicContact CG-SD 3.35Å; L270-M330 WeakPolarHBondContact CG-SD 3.37Å; L270-N333 HydrophobicContact CD1-CB 3.87Å; L270-N333 WeakPolarHBondContact CD1-ND2 3.16Å; L270-W347 HydrophobicContact CD2-CH2 4.18Å
271	K	96.1	Very high	96.2	Very high	4 Å²	4	28 Å²	28	2%	0.017	14%	0.137	C	C	.	.	H	α-helix	trans	-66.4	-39.3	-178.9	-74.9	-166.5	179.3	-174.7	0	112	V209 A211 D269 I274 A275 F315 A318	V209-K271 HydrophobicContact CG2-CB 4.08Å; A211-K271 PolarHBondContact O-NZ 3.33Å; D269-K271 PolarHBondContact O-N 2.86Å; K271-I274 PolarHBondContact O-N 3.35Å; K271-A275 WeakPolarHBondContact O-CB 3.39Å; K271-A275 PolarHBondContact O-N 2.99Å; K271-F315 HydrophobicContact CB-CE1 4.44Å; K271-A318 HydrophobicContact CG-CB 4.36Å
272	A	95.7	Very high	96.1	Very high	8 Å²	8	28 Å²	28	7%	0.066	14%	0.137	C	C	.	.	H	α-helix	trans	-66	-42.5	179.4	0	0	0	0	0	110.5	V209 D269 I274 A275 Y276	V209-A272 HydrophobicContact CG2-CB 3.78Å; D269-A272 HydrophobicContact CB-CB 3.76Å; D269-A272 PolarHBondContact O-N 3.28Å; A272-I274 PolarHBondContact O-N 2.91Å; A272-A275 WeakPolarHBondContact O-CB 3.37Å; A272-A275 PolarHBondContact O-N 3.33Å; A272-A275 VanDerWaalsContact O-N 3.15Å; A272-Y276 HydrophobicContact CB-CE2 4.47Å; A272-Y276 WeakPolarHBondContact O-CD2 3.29Å; A272-Y276 PolarHBondContact O-N 3.37Å
273	L	97	Very high	96.1	Very high	1 Å²	1	25.3 Å²	25.3	1%	0.005	12%	0.124	C	C	.	.	H	α-helix	trans	-59.1	-46.6	175.9	-169.6	163.1	0	0	0	111.5	C264 Q267 D269 L270 A275 Y276 S277 Y394 Y397 L398	C264-L273 HydrophobicContact CB-CG 4.48Å; Q267-L273 HydrophobicContact CB-CB 4.04Å; Q267-L273 HydrophobicContact CB-CG 4.45Å; D269-L273 WeakPolarHBondContact O-CB 3.46Å; D269-L273 PolarHBondContact O-N 3.28Å; L270-L273 PolarHBondContact O-N 2.98Å; L273-A275 VanDerWaalsContact C-N 3.3Å; L273-A275 PolarHBondContact O-N 3.46Å; L273-Y276 PolarHBondContact O-N 2.68Å; L273-S277 PolarHBondContact O-N 3.33Å; L273-Y394 HydrophobicContact CD2-CD2 4.4Å; L273-Y397 HydrophobicContact CD1-CD1 3.7Å; L273-Y397 HydrophobicContact CD1-CE1 3.73Å; L273-L398 HydrophobicContact CD1-CB 4.43Å; L273-L398 HydrophobicContact CD2-CB 4.2Å; L273-L398 HydrophobicContact CD2-CD1 3.88Å
274	I	97.4	Very high	96	Very high	0 Å²	0	24.2 Å²	24.2	0%	0	12%	0.117	C	C	.	.	H	α-helix	trans	-61.6	-40.2	176.1	-61	162.2	0	0	0	110.7	L270 K271 A272 S277 S278 L314 F315 A318 L398	L270-I274 WeakPolarHBondContact O-CG1 3.37Å; L270-I274 PolarHBondContact O-N 3.11Å; L270-I274 VanDerWaalsContact O-N 3.14Å; K271-I274 PolarHBondContact O-N 3.35Å; A272-I274 PolarHBondContact O-N 2.91Å; I274-S277 PolarHBondContact O-N 3.38Å; I274-S277 PolarHBondContact O-OG 3.34Å; I274-S278 PolarHBondContact O-N 3.31Å; I274-S278 VanDerWaalsContact O-N 3.11Å; I274-L314 HydrophobicContact CD1-CB 4.07Å; I274-L314 HydrophobicContact CG1-CB 4.33Å; I274-L314 HydrophobicContact CG2-CB 4Å; I274-F315 HydrophobicContact CB-CD1 4.5Å; I274-F315 HydrophobicContact CB-CE1 4.02Å; I274-F315 HydrophobicContact CB-CE2 4.5Å; I274-F315 HydrophobicContact CB-CZ 4.01Å; I274-F315 HydrophobicContact CG2-CD1 4.2Å; I274-F315 HydrophobicContact CG2-CD2 3.91Å; I274-F315 HydrophobicContact CG2-CE1 3.9Å; I274-F315 HydrophobicContact CG2-CE2 3.57Å; I274-F315 HydrophobicContact CG2-CG 4.2Å; I274-F315 HydrophobicContact CG2-CZ 3.57Å; I274-A318 HydrophobicContact CD1-CB 3.81Å; I274-L398 HydrophobicContact CG1-CD1 3.91Å
275	A	96.7	Very high	96.1	Very high	0 Å²	0	24.2 Å²	24.2	0%	0	12%	0.117	C	C	.	.	H	α-helix	trans	-65	-40.1	177	0	0	0	0	0	113.4	L204 H208 K271 A272 L273 S278 V279 F315	L204-A275 HydrophobicContact CD2-CB 3.74Å; L204-A275 WeakPolarHBondContact CD2-O 3.45Å; H208-A275 HydrophobicContact CB-CB 3.86Å; K271-A275 WeakPolarHBondContact O-CB 3.39Å; K271-A275 PolarHBondContact O-N 2.99Å; A272-A275 WeakPolarHBondContact O-CB 3.37Å; A272-A275 PolarHBondContact O-N 3.33Å; A272-A275 VanDerWaalsContact O-N 3.15Å; L273-A275 VanDerWaalsContact C-N 3.3Å; L273-A275 PolarHBondContact O-N 3.46Å; A275-S278 PolarHBondContact O-N 3.46Å; A275-S278 PolarHBondContact O-OG 3.47Å; A275-V279 PolarHBondContact O-N 3.02Å; A275-F315 HydrophobicContact CB-CZ 4.25Å
276	Y	96.8	Very high	96.1	Very high	39 Å²	39	21.8 Å²	21.8	15%	0.153	10%	0.104	C	C	.	.	H	α-helix	trans	-70.5	-33.6	173.8	-75.2	-69.6	0	0	0	112	P205 V260 V263 C264 Q267 A272 L273 S278 V279 A280	P205-Y276 HydrophobicContact CB-CE1 4.31Å; P205-Y276 HydrophobicContact CB-CE2 3.98Å; P205-Y276 HydrophobicContact CG-CD1 3.94Å; P205-Y276 HydrophobicContact CG-CD2 4.45Å; P205-Y276 HydrophobicContact CG-CE1 3.46Å; P205-Y276 VanDerWaalsContact CG-CE1 3.46Å; P205-Y276 HydrophobicContact CG-CE2 4Å; P205-Y276 HydrophobicContact CG-CG 4.41Å; P205-Y276 VanDerWaalsContact CG-CZ 3.48Å; V260-Y276 HydrophobicContact CG1-CD1 3.94Å; V260-Y276 HydrophobicContact CG1-CG 4.4Å; V260-Y276 WeakPolarHBondContact CG1-O 3.4Å; V263-Y276 HydrophobicContact CG1-CD1 4.41Å; V263-Y276 HydrophobicContact CG1-CD2 4.42Å; V263-Y276 HydrophobicContact CG1-CE1 4.3Å; V263-Y276 HydrophobicContact CG1-CE2 4.34Å; V263-Y276 HydrophobicContact CG1-CG 4.47Å; C264-Y276 WeakPolarHBondContact SG-CB 3.39Å; Q267-Y276 HydrophobicContact CG-CD2 3.84Å; Q267-Y276 HydrophobicContact CG-CE2 4.12Å; A272-Y276 HydrophobicContact CB-CE2 4.47Å; A272-Y276 WeakPolarHBondContact O-CD2 3.29Å; A272-Y276 PolarHBondContact O-N 3.37Å; L273-Y276 PolarHBondContact O-N 2.68Å; Y276-S278 VanDerWaalsContact C-N 3.28Å; Y276-S278 PolarHBondContact O-N 2.96Å; Y276-V279 WeakPolarHBondContact O-CB 3.24Å; Y276-V279 PolarHBondContact O-N 3.13Å; Y276-A280 PolarHBondContact O-N 3.21Å; Y276-A280 VanDerWaalsContact O-N 3.13Å
277	S	95.9	Very high	96.1	Very high	2 Å²	2	12.6 Å²	12.6	1%	0.014	7%	0.07	C	C	.	.	H	α-helix	trans	-61.3	-36.9	173.7	77.4	0	0	0	0	112.3	L273 I274 V279 A280 H281 Y394	L273-S277 PolarHBondContact O-N 3.33Å; I274-S277 PolarHBondContact O-N 3.38Å; I274-S277 PolarHBondContact O-OG 3.34Å; S277-V279 VanDerWaalsContact C-N 3.34Å; S277-V279 PolarHBondContact O-N 3.39Å; S277-A280 PolarHBondContact O-N 3.14Å; S277-H281 PolarHBondContact O-CD2 3.14Å; S277-H281 PolarHBondContact O-N 3.44Å; S277-H281 VanDerWaalsContact O-N 3.08Å; S277-Y394 VanDerWaalsContact CB-CE2 3.46Å
278	S	95.7	Very high	96.1	Very high	0 Å²	0	10.6 Å²	10.6	0%	0	6%	0.061	C	C	.	.	H	α-helix	trans	-68.5	-32.8	177	66.3	0	0	0	0	112.9	I274 A275 Y276 A280 M282 H307	I274-S278 PolarHBondContact O-N 3.31Å; I274-S278 VanDerWaalsContact O-N 3.11Å; A275-S278 PolarHBondContact O-N 3.46Å; A275-S278 PolarHBondContact O-OG 3.47Å; Y276-S278 VanDerWaalsContact C-N 3.28Å; Y276-S278 PolarHBondContact O-N 2.96Å; S278-A280 VanDerWaalsContact C-N 3.34Å; S278-M282 VanDerWaalsContact O-CB 3.27Å; S278-M282 WeakPolarHBondContact O-CB 3.37Å; S278-M282 WeakPolarHBondContact O-CG 3.47Å; S278-M282 PolarHBondContact O-N 3.27Å; S278-H307 WeakPolarHBondContact CA-NE2 3.4Å; S278-H307 WeakPolarHBondContact CB-NE2 3.37Å
279	V	96.5	Very high	96.1	Very high	4 Å²	4	7.2 Å²	7.2	2%	0.024	4%	0.039	C	C	.	.	H	α-helix	trans	-63	-41.2	171.1	177.6	0	0	0	0	110.8	P196 H201 L204 V260 A275 Y276 S277 G283	P196-V279 HydrophobicContact CB-CG2 4.25Å; P196-V279 HydrophobicContact CG-CG2 4.02Å; H201-V279 HydrophobicContact CB-CG1 3.89Å; H201-V279 HydrophobicContact CB-CG2 4.11Å; L204-V279 HydrophobicContact CD1-CG2 3.87Å; L204-V279 HydrophobicContact CD2-CG2 4.09Å; L204-V279 HydrophobicContact CG-CG2 4.46Å; V260-V279 HydrophobicContact CG1-CB 4.12Å; V260-V279 HydrophobicContact CG1-CG1 4.2Å; V260-V279 HydrophobicContact CG2-CG1 4.03Å; A275-V279 PolarHBondContact O-N 3.02Å; Y276-V279 WeakPolarHBondContact O-CB 3.24Å; Y276-V279 PolarHBondContact O-N 3.13Å; S277-V279 VanDerWaalsContact C-N 3.34Å; S277-V279 PolarHBondContact O-N 3.39Å; V279-G283 PolarHBondContact O-N 3.46Å
280	A	96.3	Very high	96.1	Very high	4 Å²	4	4.8 Å²	4.8	3%	0.033	3%	0.026	C	C	.	.	H	α-helix	trans	-64.3	-50.8	178.5	0	0	0	0	0	112.3	Y276 S277 S278 M282 G283 I284	Y276-A280 PolarHBondContact O-N 3.21Å; Y276-A280 VanDerWaalsContact O-N 3.13Å; S277-A280 PolarHBondContact O-N 3.14Å; S278-A280 VanDerWaalsContact C-N 3.34Å; A280-M282 PolarHBondContact O-N 3.35Å; A280-G283 PolarHBondContact O-N 3Å; A280-G283 VanDerWaalsContact O-N 3.15Å; A280-I284 PolarHBondContact O-N 3.48Å
281	H	95.7	Very high	96	Very high	1 Å²	1	5.2 Å²	5.2	1%	0.005	3%	0.029	C	C	.	.	H	α-helix	trans	-63	-42	178	-69.6	-76.5	0	0	0	111.9	S277 G283 I284 V285 L303 H307 N354 E366 Y394	S277-H281 PolarHBondContact O-CD2 3.14Å; S277-H281 PolarHBondContact O-N 3.44Å; S277-H281 VanDerWaalsContact O-N 3.08Å; H281-G283 VanDerWaalsContact C-N 3.27Å; H281-G283 PolarHBondContact O-N 3.32Å; H281-I284 PolarHBondContact O-N 3.47Å; H281-V285 WeakPolarHBondContact O-CG2 3.44Å; H281-V285 PolarHBondContact O-N 3.4Å; H281-V285 VanDerWaalsContact O-N 3.16Å; H281-L303 HydrophobicContact CB-CD2 4.31Å; H281-H307 AromaticContact CD2-CE1 3.62Å; H281-H307 AromaticContact CD2-ND1 3.72Å; H281-H307 AromaticContact CG-CE1 3.96Å; H281-H307 AromaticContact CG-ND1 3.75Å; H281-N354 PolarHBondContact CE1-O 2.83Å; H281-N354 VanDerWaalsContact CE1-O 3.31Å; H281-N354 PolarHBondContact NE2-OD1 3.01Å; H281-N354 VanDerWaalsContact NE2-OD1 3.16Å; H281-E366 IonicContact CE1-OE1 2.79Å; H281-E366 PolarHBondContact CE1-OE1 3.01Å; H281-E366 IonicContact ND1-OE1 2.66Å; H281-E366 PolarHBondContact ND1-OE1 2.94Å; H281-Y394 PolarHBondContact NE2-OH 2.98Å
282	M	95.5	Very high	95.8	Very high	2 Å²	2	7.1 Å²	7.1	1%	0.01	4%	0.039	C	C	.	.	H	α-helix	trans	-67.1	-27.1	175.9	-68.2	-64.6	158.6	0	0	113	M195 L224 K225 S278 A280 I284 V285 L286 H307	M195-M282 HydrophobicContact CE-CB 4.35Å; M195-M282 HydrophobicContact CE-SD 3.69Å; M195-M282 HydrophobicContact SD-SD 3.86Å; L224-M282 HydrophobicContact CD1-CG 4.37Å; K225-M282 HydrophobicContact CD-CE 3.91Å; K225-M282 VanDerWaalsContact NZ-CE 3.26Å; S278-M282 VanDerWaalsContact O-CB 3.27Å; S278-M282 WeakPolarHBondContact O-CB 3.37Å; S278-M282 WeakPolarHBondContact O-CG 3.47Å; S278-M282 PolarHBondContact O-N 3.27Å; A280-M282 PolarHBondContact O-N 3.35Å; M282-I284 VanDerWaalsContact C-N 3.34Å; M282-V285 WeakPolarHBondContact O-CB 3.44Å; M282-V285 PolarHBondContact O-N 3.42Å; M282-V285 HydrophobicContact SD-CG2 4.28Å; M282-L286 WeakPolarHBondContact O-CB 3.45Å; M282-L286 PolarHBondContact O-N 3.12Å; M282-H307 HydrophobicContact CE-CB 4.18Å; M282-H307 WeakPolarHBondContact CE-CD2 3.47Å
283	G	95.6	Very high	95.7	Very high	9 Å²	9	8.6 Å²	8.6	9%	0.093	5%	0.047	C	C	.	.	H	α-helix	trans	-61.3	-40.6	171.1	0	0	0	0	0	112.7	S253 V279 A280 H281 L286 S287	S253-G283 PolarHBondContact OG-O 3.03Å; V279-G283 PolarHBondContact O-N 3.46Å; A280-G283 PolarHBondContact O-N 3Å; A280-G283 VanDerWaalsContact O-N 3.15Å; H281-G283 VanDerWaalsContact C-N 3.27Å; H281-G283 PolarHBondContact O-N 3.32Å; G283-L286 PolarHBondContact O-N 3.11Å; G283-S287 PolarHBondContact O-N 3.34Å; G283-S287 PolarHBondContact O-OG 3.44Å; G283-S287 VanDerWaalsContact O-OG 3.12Å
284	I	96.1	Very high	95.5	Very high	17 Å²	17	12.8 Å²	12.8	9%	0.087	6%	0.063	C	C	.	.	H	α-helix	trans	-66.9	-43.9	175	-56.9	171.3	0	0	0	110.4	A280 H281 M282 L286 S287 G288 L369 I373 L387	A280-I284 PolarHBondContact O-N 3.48Å; H281-I284 PolarHBondContact O-N 3.47Å; M282-I284 VanDerWaalsContact C-N 3.34Å; I284-L286 VanDerWaalsContact C-N 3.3Å; I284-L286 PolarHBondContact O-N 3.38Å; I284-S287 WeakPolarHBondContact CA-OG 3.36Å; I284-S287 PolarHBondContact O-N 3.14Å; I284-S287 PolarHBondContact O-OG 3.38Å; I284-G288 PolarHBondContact O-N 2.98Å; I284-L369 HydrophobicContact CG2-CB 3.99Å; I284-L369 HydrophobicContact CG2-CD1 3.96Å; I284-I373 HydrophobicContact CG2-CD1 4.24Å; I284-L387 HydrophobicContact CD1-CB 4.47Å; I284-L387 HydrophobicContact CG1-CD1 4.21Å
285	V	96.8	Very high	95.4	Very high	0 Å²	0	19 Å²	19	0%	0	9%	0.087	C	C	.	.	H	α-helix	trans	-56.3	-46.7	174.2	-179.9	0	0	0	0	110.6	M195 H281 M282 G288 L289 L303 M304 L369	M195-V285 HydrophobicContact CE-CB 4.03Å; M195-V285 HydrophobicContact CE-CG1 3.65Å; H281-V285 WeakPolarHBondContact O-CG2 3.44Å; H281-V285 PolarHBondContact O-N 3.4Å; H281-V285 VanDerWaalsContact O-N 3.16Å; M282-V285 WeakPolarHBondContact O-CB 3.44Å; M282-V285 PolarHBondContact O-N 3.42Å; M282-V285 HydrophobicContact SD-CG2 4.28Å; V285-G288 PolarHBondContact O-N 3.05Å; V285-L289 HydrophobicContact CG1-CD1 3.83Å; V285-L289 HydrophobicContact CG1-CG 4.21Å; V285-L289 WeakPolarHBondContact O-CB 3.36Å; V285-L289 VanDerWaalsContact O-CG 3.29Å; V285-L289 WeakPolarHBondContact O-CG 3.44Å; V285-L289 PolarHBondContact O-N 3.48Å; V285-L303 HydrophobicContact CG2-CB 4.03Å; V285-L303 HydrophobicContact CG2-CD2 3.17Å; V285-L303 HydrophobicContact CG2-CG 4.16Å; V285-M304 HydrophobicContact CG1-CG 4.04Å; V285-L369 HydrophobicContact CG2-CD1 4.36Å
286	L	96.6	Very high	95.3	Very high	3 Å²	3	19 Å²	19	2%	0.016	9%	0.087	C	C	.	.	H	α-helix	trans	-63	-43.8	-178.9	-170.7	142.9	0	0	0	111.7	L192 M195 M197 M282 G283 I284 L290	L192-L286 HydrophobicContact CD2-CD1 3.72Å; L192-L286 HydrophobicContact CD2-CG 4.43Å; M195-L286 HydrophobicContact CB-CD1 4.2Å; M197-L286 HydrophobicContact CE-CD1 4.31Å; M197-L286 HydrophobicContact CE-CD2 3.77Å; M282-L286 WeakPolarHBondContact O-CB 3.45Å; M282-L286 PolarHBondContact O-N 3.12Å; G283-L286 PolarHBondContact O-N 3.11Å; I284-L286 VanDerWaalsContact C-N 3.3Å; I284-L286 PolarHBondContact O-N 3.38Å; L286-L290 HydrophobicContact CD2-CD1 3.53Å; L286-L290 HydrophobicContact CG-CD1 4.13Å; L286-L290 WeakPolarHBondContact O-CD1 3.38Å; L286-L290 VanDerWaalsContact O-CG 3.24Å; L286-L290 WeakPolarHBondContact O-CG 3.42Å; L286-L290 PolarHBondContact O-N 3.1Å
287	S	96	Very high	95.2	Very high	0 Å²	0	18 Å²	18	0%	0	8%	0.084	C	C	.	.	H	α-helix	trans	-60.8	-45.4	173.5	36.6	0	0	0	0	112.2	S253 G283 I284 L290 T291 I373	S253-S287 WeakPolarHBondContact OG-CB 3.01Å; G283-S287 PolarHBondContact O-N 3.34Å; G283-S287 PolarHBondContact O-OG 3.44Å; G283-S287 VanDerWaalsContact O-OG 3.12Å; I284-S287 WeakPolarHBondContact CA-OG 3.36Å; I284-S287 PolarHBondContact O-N 3.14Å; I284-S287 PolarHBondContact O-OG 3.38Å; S287-L290 PolarHBondContact O-N 3.1Å; S287-T291 WeakPolarHBondContact O-CG2 3.36Å; S287-T291 PolarHBondContact O-N 3.47Å; S287-I373 VanDerWaalsContact OG-CD1 3.26Å; S287-I373 WeakPolarHBondContact OG-CD1 3.39Å
288	G	95.9	Very high	95.1	Very high	0 Å²	0	17.9 Å²	17.9	0%	0	8%	0.083	C	C	.	.	H	α-helix	trans	-66.2	-41.7	-178.5	0	0	0	0	0	113.1	I284 V285 L290 T291	I284-G288 PolarHBondContact O-N 2.98Å; V285-G288 PolarHBondContact O-N 3.05Å; G288-L290 VanDerWaalsContact C-N 3.28Å; G288-L290 PolarHBondContact O-N 3.01Å; G288-T291 PolarHBondContact O-N 3.34Å; G288-T291 PolarHBondContact O-OG1 2.97Å
289	L	95.4	Very high	95.1	Very high	2 Å²	2	17.9 Å²	17.9	1%	0.01	8%	0.083	C	C	.	.	H	α-helix	trans	-54.8	-44.8	174	-80.2	171.7	0	0	0	111.9	M195 L232 V285 T291 M292 L297 S300	M195-L289 HydrophobicContact CE-CD1 4.43Å; L232-L289 HydrophobicContact CD1-CD2 4.21Å; L232-L289 HydrophobicContact CD2-CD2 3.24Å; L232-L289 HydrophobicContact CG-CD2 3.61Å; V285-L289 HydrophobicContact CG1-CD1 3.83Å; V285-L289 HydrophobicContact CG1-CG 4.21Å; V285-L289 WeakPolarHBondContact O-CB 3.36Å; V285-L289 VanDerWaalsContact O-CG 3.29Å; V285-L289 WeakPolarHBondContact O-CG 3.44Å; V285-L289 PolarHBondContact O-N 3.48Å; L289-T291 VanDerWaalsContact C-N 3.31Å; L289-T291 PolarHBondContact O-N 2.9Å; L289-M292 PolarHBondContact O-N 2.98Å; L289-L297 HydrophobicContact CD2-CD2 4.15Å; L289-S300 VanDerWaalsContact CD2-CB 3.5Å; L289-S300 WeakPolarHBondContact CD2-OG 3.47Å
290	L	95.4	Very high	95.1	Very high	1 Å²	1	17.7 Å²	17.7	1%	0.005	8%	0.082	C	C	.	.	H	α-helix	trans	-77.6	-14	-173.9	-66.8	169.4	0	0	0	113.8	M231 I235 N242 W249 I250 L286 S287 G288 M292	M231-L290 HydrophobicContact CE-CD2 3.98Å; I235-L290 HydrophobicContact CD1-CD2 4.29Å; N242-L290 WeakPolarHBondContact OD1-CD2 3.27Å; W249-L290 HydrophobicContact CB-CD1 3.35Å; W249-L290 HydrophobicContact CG-CD1 4.24Å; I250-L290 HydrophobicContact CD1-CB 4.22Å; I250-L290 HydrophobicContact CG1-CB 3.89Å; L286-L290 HydrophobicContact CD2-CD1 3.53Å; L286-L290 HydrophobicContact CG-CD1 4.13Å; L286-L290 WeakPolarHBondContact O-CD1 3.38Å; L286-L290 VanDerWaalsContact O-CG 3.24Å; L286-L290 WeakPolarHBondContact O-CG 3.42Å; L286-L290 PolarHBondContact O-N 3.1Å; S287-L290 PolarHBondContact O-N 3.1Å; G288-L290 VanDerWaalsContact C-N 3.28Å; G288-L290 PolarHBondContact O-N 3.01Å; L290-M292 PolarHBondContact O-N 3.31Å
291	T	94	Very high	95	Very high	13 Å²	13	17.6 Å²	17.6	8%	0.08	8%	0.081	C	C	.	.	T	Hydrogen-bonded Turn	trans	-68.4	-17.7	172.5	66	0	0	0	0	113.8	I250 S287 G288 L289 T293 I373 W376	I250-T291 HydrophobicContact CD1-CG2 4.18Å; S287-T291 WeakPolarHBondContact O-CG2 3.36Å; S287-T291 PolarHBondContact O-N 3.47Å; G288-T291 PolarHBondContact O-N 3.34Å; G288-T291 PolarHBondContact O-OG1 2.97Å; L289-T291 VanDerWaalsContact C-N 3.31Å; L289-T291 PolarHBondContact O-N 2.9Å; T291-T293 PolarHBondContact O-N 3.35Å; T291-T293 PolarHBondContact OG1-OG1 3.5Å; T291-T293 VanDerWaalsContact OG1-OG1 3.11Å; T291-I373 HydrophobicContact CG2-CG1 4.31Å; T291-W376 HydrophobicContact CG2-CB 3.88Å; T291-W376 HydrophobicContact CG2-CG 4.2Å
292	M	92	Very high	95	Very high	44 Å²	44	17.6 Å²	17.6	22%	0.217	8%	0.081	C	C	.	.			trans	59.5	10.7	-177.4	-62.8	-57.8	-67.5	0	0	116.2	I235 Q239 N242 L289 L290	I235-M292 HydrophobicContact CB-SD 4.47Å; I235-M292 HydrophobicContact CG2-CE 3.36Å; I235-M292 HydrophobicContact CG2-SD 3.01Å; I235-M292 WeakPolarHBondContact CG2-SD 3.42Å; Q239-M292 HydrophobicContact CG-CE 4.01Å; N242-M292 WeakPolarHBondContact ND2-CG 3.35Å; N242-M292 PolarHBondContact ND2-SD 3.07Å; N242-M292 VanDerWaalsContact ND2-SD 3.38Å; L289-M292 PolarHBondContact O-N 2.98Å; L290-M292 PolarHBondContact O-N 3.31Å
293	T	93.1	Very high	95.1	Very high	38 Å²	38	17.5 Å²	17.5	23%	0.233	8%	0.081	C	C	.	.			trans	-79	149.8	175.2	61.4	0	0	0	0	110.5	T291 W295 G296 L297 S372	T291-T293 PolarHBondContact O-N 3.35Å; T291-T293 PolarHBondContact OG1-OG1 3.5Å; T291-T293 VanDerWaalsContact OG1-OG1 3.11Å; T293-W295 VanDerWaalsContact C-N 3.3Å; T293-W295 PolarHBondContact O-N 2.92Å; T293-G296 PolarHBondContact O-N 3.35Å; T293-G296 VanDerWaalsContact O-N 3.11Å; T293-G296 PolarHBondContact OG1-N 3.02Å; T293-G296 VanDerWaalsContact OG1-N 3.11Å; T293-L297 WeakPolarHBondContact O-CG 3.2Å; T293-L297 PolarHBondContact O-N 2.72Å; T293-S372 WeakPolarHBondContact OG1-CB 3.4Å
294	Y	93.2	Very high	95.1	Very high	89 Å²	89	17 Å²	17	35%	0.349	8%	0.076	S	C	.	.	H	α-helix	trans	-53.7	-47.9	174.8	-179.8	-98.9	0	0	0	111.7	G296 L297 C298 M443 L444 L446	Y294-G296 VanDerWaalsContact C-N 3.33Å; Y294-G296 PolarHBondContact O-N 3.14Å; Y294-L297 PolarHBondContact O-N 3.17Å; Y294-C298 PolarHBondContact O-N 3.03Å; Y294-C298 PolarHBondContact O-SG 2.88Å; Y294-M443 PolarHBondContact OH-O 3.07Å; Y294-L444 WeakPolarHBondContact OH-CD2 3.33Å; Y294-L446 HydrophobicContact CD2-CB 4.22Å; Y294-L446 HydrophobicContact CD2-CD1 4.17Å; Y294-L446 HydrophobicContact CE2-CB 3.89Å
295	W	93.7	Very high	95.1	Very high	131 Å²	131	16.4 Å²	16.4	50%	0.496	7%	0.073	S	C	.	.	H	α-helix	trans	-59.5	-41	177.1	-62	88.7	0	0	0	112.4	T293 G299 Y368	T293-W295 VanDerWaalsContact C-N 3.3Å; T293-W295 PolarHBondContact O-N 2.92Å; W295-G299 PolarHBondContact O-N 2.97Å; W295-Y368 HydrophobicContact CB-CD1 4.31Å; W295-Y368 HydrophobicContact CD2-CD1 4.08Å; W295-Y368 HydrophobicContact CD2-CE1 4.05Å; W295-Y368 AromaticContact CE3-CD1 3.15Å; W295-Y368 HydrophobicContact CE3-CD1 3.15Å; W295-Y368 AromaticContact CE3-CE1 2.98Å; W295-Y368 HydrophobicContact CE3-CE1 2.98Å; W295-Y368 HydrophobicContact CE3-CG 4.04Å; W295-Y368 AromaticContact CE3-CZ 3.83Å; W295-Y368 HydrophobicContact CH2-CE1 4.12Å; W295-Y368 AromaticContact CZ3-CD1 3.72Å; W295-Y368 HydrophobicContact CZ3-CD1 3.72Å; W295-Y368 AromaticContact CZ3-CE1 3.02Å; W295-Y368 HydrophobicContact CZ3-CE1 3.02Å; W295-Y368 HydrophobicContact CZ3-CE2 4.33Å; W295-Y368 AromaticContact CZ3-CZ 3.43Å; W295-Y368 VanDerWaalsContact CZ3-CZ 3.43Å
296	G	94.8	Very high	95.1	Very high	0 Å²	0	16.4 Å²	16.4	0%	0	7%	0.073	C	C	.	.	H	α-helix	trans	-66.9	-41.8	178.3	0	0	0	0	0	112.8	T293 Y294 S300 S372	T293-G296 PolarHBondContact O-N 3.35Å; T293-G296 VanDerWaalsContact O-N 3.11Å; T293-G296 PolarHBondContact OG1-N 3.02Å; T293-G296 VanDerWaalsContact OG1-N 3.11Å; Y294-G296 VanDerWaalsContact C-N 3.33Å; Y294-G296 PolarHBondContact O-N 3.14Å; G296-S300 VanDerWaalsContact O-CB 3.27Å; G296-S300 WeakPolarHBondContact O-CB 3.15Å; G296-S300 PolarHBondContact O-N 3.37Å; G296-S300 PolarHBondContact O-OG 3.31Å; G296-S372 VanDerWaalsContact CA-CB 3.45Å; G296-S372 WeakPolarHBondContact CA-OG 3.4Å
297	L	94.5	Very high	95.1	Very high	18 Å²	18	16.3 Å²	16.3	9%	0.094	7%	0.072	C	C	.	.	H	α-helix	trans	-64.9	-50.5	177.1	-70.5	177.4	0	0	0	111	L232 L289 T293 Y294 G299 S300 Y301 W445 L446	L232-L297 HydrophobicContact CD2-CD2 3.64Å; L289-L297 HydrophobicContact CD2-CD2 4.15Å; T293-L297 WeakPolarHBondContact O-CG 3.2Å; T293-L297 PolarHBondContact O-N 2.72Å; Y294-L297 PolarHBondContact O-N 3.17Å; L297-G299 PolarHBondContact O-N 3.29Å; L297-S300 PolarHBondContact O-N 3.33Å; L297-S300 PolarHBondContact O-OG 2.87Å; L297-Y301 PolarHBondContact O-N 3.25Å; L297-W445 HydrophobicContact CB-CZ2 3.89Å; L297-W445 WeakPolarHBondContact O-CZ2 3.34Å; L297-L446 HydrophobicContact CB-CD1 3.81Å; L297-L446 HydrophobicContact CD1-CD1 3.59Å; L297-L446 HydrophobicContact CG-CD1 4.35Å
298	C	94.9	Very high	95.1	Very high	0 Å²	0	16.3 Å²	16.3	0%	0	7%	0.072	C	C	.	.	H	α-helix	trans	-66.8	-39.6	178.2	-53.1	0	0	0	0	112.6	Y294 S300 Y301 T302 M443 W445	Y294-C298 PolarHBondContact O-N 3.03Å; Y294-C298 PolarHBondContact O-SG 2.88Å; C298-S300 VanDerWaalsContact C-N 3.32Å; C298-S300 PolarHBondContact O-N 3.22Å; C298-Y301 PolarHBondContact O-N 3.07Å; C298-T302 WeakPolarHBondContact O-CG2 3.41Å; C298-T302 PolarHBondContact O-N 2.92Å; C298-T302 VanDerWaalsContact O-N 3.14Å; C298-T302 PolarHBondContact O-OG1 3.31Å; C298-T302 VanDerWaalsContact O-OG1 3.12Å; C298-M443 HydrophobicContact CB-CE 3.65Å; C298-M443 PolarHBondContact SG-O 2.72Å; C298-W445 PolarHBondContact SG-NE1 3.11Å; C298-W445 VanDerWaalsContact SG-NE1 3.38Å
299	G	95.4	Very high	95.1	Very high	0 Å²	0	16.5 Å²	16.5	0%	0	7%	0.073	C	C	.	.	H	α-helix	trans	-62.1	-37.8	175.2	0	0	0	0	0	113	W295 L297 Y301 T302 L303	W295-G299 PolarHBondContact O-N 2.97Å; L297-G299 PolarHBondContact O-N 3.29Å; G299-Y301 PolarHBondContact O-N 3.32Å; G299-T302 WeakPolarHBondContact CA-OG1 3.22Å; G299-T302 PolarHBondContact O-OG1 3.42Å; G299-L303 WeakPolarHBondContact O-CB 3.4Å; G299-L303 PolarHBondContact O-N 3.47Å
300	S	95.7	Very high	95.1	Very high	0 Å²	0	16.4 Å²	16.4	0%	0	7%	0.073	C	C	.	.	H	α-helix	trans	-64.7	-40.7	177.8	73.7	0	0	0	0	112.4	L289 G296 L297 C298 M304	L289-S300 VanDerWaalsContact CD2-CB 3.5Å; L289-S300 WeakPolarHBondContact CD2-OG 3.47Å; G296-S300 VanDerWaalsContact O-CB 3.27Å; G296-S300 WeakPolarHBondContact O-CB 3.15Å; G296-S300 PolarHBondContact O-N 3.37Å; G296-S300 PolarHBondContact O-OG 3.31Å; L297-S300 PolarHBondContact O-N 3.33Å; L297-S300 PolarHBondContact O-OG 2.87Å; C298-S300 VanDerWaalsContact C-N 3.32Å; C298-S300 PolarHBondContact O-N 3.22Å; S300-M304 WeakPolarHBondContact O-CB 3.31Å; S300-M304 VanDerWaalsContact O-CG 3.26Å; S300-M304 WeakPolarHBondContact O-CG 3.16Å; S300-M304 PolarHBondContact O-N 3.1Å
301	Y	95.3	Very high	95.2	Very high	1 Å²	1	16.4 Å²	16.4	0%	0.004	7%	0.073	C	C	.	.	H	α-helix	trans	-66.8	-48	179.8	-176.8	-129.1	0	0	0	112.7	M56 L57 G60 L61 L297 C298 G299 L303 M304 I305 F442 W445	M56-Y301 PolarHBondContact O-OH 3.46Å; L57-Y301 HydrophobicContact CD2-CD2 4.17Å; L57-Y301 HydrophobicContact CD2-CE2 4.06Å; L57-Y301 WeakPolarHBondContact O-CE2 3.31Å; L57-Y301 PolarHBondContact O-OH 3.37Å; G60-Y301 VanDerWaalsContact CA-OH 3.25Å; G60-Y301 WeakPolarHBondContact CA-OH 3.48Å; G60-Y301 PolarHBondContact N-OH 2.77Å; L61-Y301 HydrophobicContact CG-CE2 4.23Å; L297-Y301 PolarHBondContact O-N 3.25Å; C298-Y301 PolarHBondContact O-N 3.07Å; G299-Y301 PolarHBondContact O-N 3.32Å; Y301-L303 VanDerWaalsContact C-N 3.34Å; Y301-L303 PolarHBondContact O-N 2.87Å; Y301-M304 HydrophobicContact CD2-CE 4.23Å; Y301-M304 WeakPolarHBondContact O-CB 3.45Å; Y301-M304 PolarHBondContact O-N 3.24Å; Y301-I305 HydrophobicContact CD1-CD1 4.35Å; Y301-I305 HydrophobicContact CD2-CD1 4.25Å; Y301-I305 HydrophobicContact CE1-CD1 3.87Å; Y301-I305 HydrophobicContact CE2-CD1 3.78Å; Y301-I305 HydrophobicContact CE2-CG1 4.38Å; Y301-I305 PolarHBondContact O-N 3.37Å; Y301-I305 VanDerWaalsContact O-N 3.14Å; Y301-F442 HydrophobicContact CD1-CB 4.11Å; Y301-F442 HydrophobicContact CD1-CD1 4.31Å; Y301-F442 WeakPolarHBondContact CD1-O 3.39Å; Y301-F442 HydrophobicContact CE1-CB 4.16Å; Y301-F442 AromaticContact CE1-CD1 3.64Å; Y301-F442 HydrophobicContact CE1-CD1 3.64Å; Y301-F442 HydrophobicContact CE1-CG 4.4Å; Y301-W445 HydrophobicContact CD1-CD2 4.16Å; Y301-W445 AromaticContact CD1-CE3 3.44Å; Y301-W445 HydrophobicContact CD1-CE3 3.44Å; Y301-W445 VanDerWaalsContact CD1-CE3 3.44Å; Y301-W445 AromaticContact CD1-CZ3 3.88Å; Y301-W445 HydrophobicContact CD1-CZ3 3.88Å; Y301-W445 AromaticContact CD2-CE3 3.67Å; Y301-W445 HydrophobicContact CD2-CE3 3.67Å; Y301-W445 HydrophobicContact CD2-CH2 4.32Å; Y301-W445 AromaticContact CD2-CZ3 3.29Å; Y301-W445 HydrophobicContact CD2-CZ3 3.29Å; Y301-W445 AromaticContact CE1-CE3 3.93Å; Y301-W445 HydrophobicContact CE1-CE3 3.93Å; Y301-W445 HydrophobicContact CE2-CE3 4.12Å; Y301-W445 HydrophobicContact CE2-CZ3 4.04Å; Y301-W445 HydrophobicContact CG-CD2 4.22Å; Y301-W445 AromaticContact CG-CE3 3.28Å; Y301-W445 HydrophobicContact CG-CE3 3.28Å; Y301-W445 HydrophobicContact CG-CH2 4.07Å; Y301-W445 AromaticContact CG-CZ3 3.18Å; Y301-W445 HydrophobicContact CG-CZ3 3.18Å
302	T	95.9	Very high	95.3	Very high	1 Å²	1	15.8 Å²	15.8	1%	0.006	7%	0.069	C	C	.	.	H	α-helix	trans	-61	-45.4	179.4	54.6	0	0	0	0	110.5	C298 G299 M304 I305 A306 L364 G365 F442 M443	C298-T302 WeakPolarHBondContact O-CG2 3.41Å; C298-T302 PolarHBondContact O-N 2.92Å; C298-T302 VanDerWaalsContact O-N 3.14Å; C298-T302 PolarHBondContact O-OG1 3.31Å; C298-T302 VanDerWaalsContact O-OG1 3.12Å; G299-T302 WeakPolarHBondContact CA-OG1 3.22Å; G299-T302 PolarHBondContact O-OG1 3.42Å; T302-M304 PolarHBondContact O-N 3.21Å; T302-I305 PolarHBondContact O-N 3.27Å; T302-A306 WeakPolarHBondContact O-CB 3.34Å; T302-A306 PolarHBondContact O-N 2.94Å; T302-L364 HydrophobicContact CG2-CD2 4.22Å; T302-G365 WeakPolarHBondContact OG1-CA 3.4Å; T302-F442 HydrophobicContact CG2-CB 3.51Å; T302-M443 HydrophobicContact CG2-SD 3.35Å; T302-M443 WeakPolarHBondContact CG2-SD 3.13Å
303	L	96.2	Very high	95.6	Very high	0 Å²	0	13.7 Å²	13.7	0%	0	6%	0.059	C	C	.	.	H	α-helix	trans	-65.8	-36.6	175.9	-157.1	98.1	0	0	0	112.5	H281 V285 G299 Y301 I305 A306 H307 E366 L369	H281-L303 HydrophobicContact CB-CD2 4.31Å; V285-L303 HydrophobicContact CG2-CB 4.03Å; V285-L303 HydrophobicContact CG2-CD2 3.17Å; V285-L303 HydrophobicContact CG2-CG 4.16Å; G299-L303 WeakPolarHBondContact O-CB 3.4Å; G299-L303 PolarHBondContact O-N 3.47Å; Y301-L303 VanDerWaalsContact C-N 3.34Å; Y301-L303 PolarHBondContact O-N 2.87Å; L303-I305 VanDerWaalsContact C-N 3.32Å; L303-I305 PolarHBondContact O-N 3.25Å; L303-A306 PolarHBondContact O-N 3.48Å; L303-H307 WeakPolarHBondContact O-CB 3.45Å; L303-H307 PolarHBondContact O-N 2.71Å; L303-E366 HydrophobicContact CD1-CB 4.4Å; L303-E366 HydrophobicContact CD1-CG 3.36Å; L303-L369 HydrophobicContact CB-CD1 3.99Å; L303-L369 HydrophobicContact CD1-CD1 4.32Å; L303-L369 HydrophobicContact CD2-CD1 4.06Å; L303-L369 HydrophobicContact CG-CD1 4.34Å
304	M	96.6	Very high	95.7	Very high	0 Å²	0	12 Å²	12	0%	0	5%	0.048	C	C	.	.	H	α-helix	trans	-58.4	-44.1	175.9	-84	-168.5	-62.9	0	0	111.8	K225 L232 V285 S300 Y301 T302 G308	K225-M304 HydrophobicContact CB-SD 4.41Å; K225-M304 WeakPolarHBondContact CE-O 3.38Å; K225-M304 HydrophobicContact CG-CB 3.88Å; K225-M304 HydrophobicContact CG-CG 4.1Å; K225-M304 HydrophobicContact CG-SD 4.29Å; L232-M304 HydrophobicContact CD1-CE 3.57Å; V285-M304 HydrophobicContact CG1-CG 4.04Å; S300-M304 WeakPolarHBondContact O-CB 3.31Å; S300-M304 VanDerWaalsContact O-CG 3.26Å; S300-M304 WeakPolarHBondContact O-CG 3.16Å; S300-M304 PolarHBondContact O-N 3.1Å; Y301-M304 HydrophobicContact CD2-CE 4.23Å; Y301-M304 WeakPolarHBondContact O-CB 3.45Å; Y301-M304 PolarHBondContact O-N 3.24Å; T302-M304 PolarHBondContact O-N 3.21Å; M304-G308 PolarHBondContact O-N 3.28Å
305	I	95.9	Very high	95.9	Very high	4 Å²	4	7.8 Å²	7.8	2%	0.021	3%	0.032	C	C	.	.	H	α-helix	trans	-70	-49.2	178.5	-63.9	172.8	0	0	0	110.4	L64 Y301 T302 L303 H307 G308 L309 L361 L435 F442	L64-I305 HydrophobicContact CD1-CG2 4.5Å; Y301-I305 HydrophobicContact CD1-CD1 4.35Å; Y301-I305 HydrophobicContact CD2-CD1 4.25Å; Y301-I305 HydrophobicContact CE1-CD1 3.87Å; Y301-I305 HydrophobicContact CE2-CD1 3.78Å; Y301-I305 HydrophobicContact CE2-CG1 4.38Å; Y301-I305 PolarHBondContact O-N 3.37Å; Y301-I305 VanDerWaalsContact O-N 3.14Å; T302-I305 PolarHBondContact O-N 3.27Å; L303-I305 VanDerWaalsContact C-N 3.32Å; L303-I305 PolarHBondContact O-N 3.25Å; I305-H307 PolarHBondContact O-N 3.07Å; I305-G308 PolarHBondContact O-N 3.36Å; I305-G308 VanDerWaalsContact O-N 3.16Å; I305-L309 PolarHBondContact O-N 3.42Å; I305-L361 HydrophobicContact CB-CD2 4.32Å; I305-L361 HydrophobicContact CG2-CD2 4.11Å; I305-L435 HydrophobicContact CG2-CD1 4.39Å; I305-F442 HydrophobicContact CD1-CD1 3.26Å; I305-F442 HydrophobicContact CD1-CE1 3.32Å; I305-F442 HydrophobicContact CD1-CG 4.3Å; I305-F442 HydrophobicContact CD1-CZ 4.38Å
306	A	96.1	Very high	96	Very high	0 Å²	0	1.7 Å²	1.7	0%	0	1%	0.009	C	C	.	.	H	α-helix	trans	-60.5	-49.2	-177.7	0	0	0	0	0	111.8	T302 L303 G308 L309 C310 L361 N362	T302-A306 WeakPolarHBondContact O-CB 3.34Å; T302-A306 PolarHBondContact O-N 2.94Å; L303-A306 PolarHBondContact O-N 3.48Å; A306-G308 VanDerWaalsContact C-N 3.29Å; A306-G308 PolarHBondContact O-N 2.62Å; A306-L309 PolarHBondContact O-N 3.28Å; A306-C310 WeakPolarHBondContact O-CB 3.2Å; A306-C310 PolarHBondContact O-N 3.35Å; A306-L361 HydrophobicContact CB-CB 3.7Å; A306-L361 HydrophobicContact CB-CD2 3.6Å; A306-L361 HydrophobicContact CB-CG 3.88Å; A306-N362 HydrophobicContact CB-CB 4.38Å; A306-N362 WeakPolarHBondContact CB-OD1 2.88Å
307	H	96.5	Very high	96.1	Very high	1 Å²	1	1.7 Å²	1.7	1%	0.005	1%	0.009	C	C	.	.	H	α-helix	trans	-66.6	-31.7	177.4	-172.4	79.2	0	0	0	111.7	S278 H281 M282 L303 I305 L309 C310 S311 N362	S278-H307 WeakPolarHBondContact CA-NE2 3.4Å; S278-H307 WeakPolarHBondContact CB-NE2 3.37Å; H281-H307 AromaticContact CD2-CE1 3.62Å; H281-H307 AromaticContact CD2-ND1 3.72Å; H281-H307 AromaticContact CG-CE1 3.96Å; H281-H307 AromaticContact CG-ND1 3.75Å; M282-H307 HydrophobicContact CE-CB 4.18Å; M282-H307 WeakPolarHBondContact CE-CD2 3.47Å; L303-H307 WeakPolarHBondContact O-CB 3.45Å; L303-H307 PolarHBondContact O-N 2.71Å; I305-H307 PolarHBondContact O-N 3.07Å; H307-L309 VanDerWaalsContact C-N 3.35Å; H307-L309 PolarHBondContact O-N 2.96Å; H307-C310 PolarHBondContact O-N 2.91Å; H307-S311 VanDerWaalsContact O-CB 3.27Å; H307-S311 WeakPolarHBondContact O-CB 3.32Å; H307-S311 PolarHBondContact O-N 3.48Å; H307-S311 PolarHBondContact O-OG 2.89Å; H307-N362 PolarHBondContact N-OD1 3.37Å
308	G	96.3	Very high	96.1	Very high	0 Å²	0	0.9 Å²	0.9	0%	0	1%	0.005	C	C	.	.	H	α-helix	trans	-56.9	-44.5	172.9	0	0	0	0	0	113.3	K225 M304 I305 A306 S312	K225-G308 VanDerWaalsContact NZ-CA 3.33Å; M304-G308 PolarHBondContact O-N 3.28Å; I305-G308 PolarHBondContact O-N 3.36Å; I305-G308 VanDerWaalsContact O-N 3.16Å; A306-G308 VanDerWaalsContact C-N 3.29Å; A306-G308 PolarHBondContact O-N 2.62Å; G308-S312 WeakPolarHBondContact O-CB 3.37Å; G308-S312 PolarHBondContact O-OG 3.48Å
309	L	96.3	Very high	96.1	Very high	4 Å²	4	1 Å²	1	2%	0.021	1%	0.006	C	C	.	.	H	α-helix	trans	-75.8	-41.4	176.8	-66.3	170.7	0	0	0	112.5	L64 I305 A306 H307 S312 G313 H428 P431 L432 L435	L64-L309 HydrophobicContact CD1-CD2 3.77Å; L64-L309 HydrophobicContact CD1-CG 3.76Å; I305-L309 PolarHBondContact O-N 3.42Å; A306-L309 PolarHBondContact O-N 3.28Å; H307-L309 VanDerWaalsContact C-N 3.35Å; H307-L309 PolarHBondContact O-N 2.96Å; L309-S312 PolarHBondContact O-OG 2.81Å; L309-G313 PolarHBondContact O-N 3.32Å; L309-H428 PolarHBondContact O-CD2 3.16Å; L309-P431 HydrophobicContact CD1-CB 4Å; L309-L432 HydrophobicContact CB-CD1 4.36Å; L309-L432 HydrophobicContact CD1-CB 4.4Å; L309-L435 HydrophobicContact CD1-CD1 4.34Å
310	C	96.5	Very high	96.1	Very high	0 Å²	0	1.1 Å²	1.1	0%	0	1%	0.006	C	C	.	.	H	α-helix	trans	-66.3	-51	-178.2	-170.6	0	0	0	0	112.5	A306 H307 G313 L314 L432	A306-C310 WeakPolarHBondContact O-CB 3.2Å; A306-C310 PolarHBondContact O-N 3.35Å; H307-C310 PolarHBondContact O-N 2.91Å; C310-G313 PolarHBondContact O-N 2.94Å; C310-L314 WeakPolarHBondContact O-CG 3.48Å; C310-L314 PolarHBondContact O-N 2.91Å; C310-L432 HydrophobicContact CB-CD1 3.76Å
311	S	96.4	Very high	95.9	Very high	1 Å²	1	1.2 Å²	1.2	1%	0.007	1%	0.007	C	C	.	.	H	α-helix	trans	-66	-40.3	-176.9	59	0	0	0	0	112.4	H307 G313 L314 F315	H307-S311 VanDerWaalsContact O-CB 3.27Å; H307-S311 WeakPolarHBondContact O-CB 3.32Å; H307-S311 PolarHBondContact O-N 3.48Å; H307-S311 PolarHBondContact O-OG 2.89Å; S311-G313 VanDerWaalsContact C-N 3.32Å; S311-G313 PolarHBondContact O-N 2.95Å; S311-L314 PolarHBondContact O-N 3.47Å; S311-F315 WeakPolarHBondContact O-CD2 3.29Å; S311-F315 PolarHBondContact O-N 3.31Å
312	S	96.8	Very high	95.8	Very high	0 Å²	0	3.3 Å²	3.3	0%	0	2%	0.015	C	C	.	.	H	α-helix	trans	-62.1	-39.5	174.6	52.5	0	0	0	0	112	G308 L309 F315 C316 H428	G308-S312 WeakPolarHBondContact O-CB 3.37Å; G308-S312 PolarHBondContact O-OG 3.48Å; L309-S312 PolarHBondContact O-OG 2.81Å; S312-F315 PolarHBondContact O-N 3.35Å; S312-C316 PolarHBondContact O-N 2.95Å; S312-H428 PolarHBondContact OG-CD2 3.06Å; S312-H428 VanDerWaalsContact OG-CD2 3.23Å; S312-H428 PolarHBondContact OG-NE2 3.04Å
313	G	96.9	Very high	95.5	Very high	0 Å²	0	5.5 Å²	5.5	0%	0	3%	0.026	C	C	.	.	H	α-helix	trans	-63	-44.2	173.3	0	0	0	0	0	113.1	L309 C310 S311 C316 L317 L350 H428	L309-G313 PolarHBondContact O-N 3.32Å; C310-G313 PolarHBondContact O-N 2.94Å; S311-G313 VanDerWaalsContact C-N 3.32Å; S311-G313 PolarHBondContact O-N 2.95Å; G313-C316 PolarHBondContact O-N 2.88Å; G313-C316 VanDerWaalsContact O-N 3.17Å; G313-L317 PolarHBondContact O-N 3.27Å; G313-L350 VanDerWaalsContact C-CD1 3.49Å; G313-H428 PolarHBondContact N-CD2 3.45Å; G313-H428 VanDerWaalsContact N-CD2 3.25Å
314	L	96.8	Very high	95.2	Very high	1 Å²	1	7 Å²	7	1%	0.005	3%	0.031	C	C	.	.	H	α-helix	trans	-62.7	-41.7	176.3	-71	174.7	0	0	0	112.3	I274 C310 S311 C316 L317 A318 L350 N354	I274-L314 HydrophobicContact CD1-CB 4.07Å; I274-L314 HydrophobicContact CG1-CB 4.33Å; I274-L314 HydrophobicContact CG2-CB 4Å; C310-L314 WeakPolarHBondContact O-CG 3.48Å; C310-L314 PolarHBondContact O-N 2.91Å; S311-L314 PolarHBondContact O-N 3.47Å; L314-C316 VanDerWaalsContact C-N 3.27Å; L314-C316 PolarHBondContact O-N 2.94Å; L314-L317 HydrophobicContact CD2-CD1 4.42Å; L314-L317 PolarHBondContact O-N 3.05Å; L314-A318 PolarHBondContact O-N 3.18Å; L314-L350 HydrophobicContact CD2-CB 3.91Å; L314-L350 HydrophobicContact CG-CB 4.46Å; L314-N354 HydrophobicContact CD1-CB 4.1Å
315	F	97.2	Very high	94.9	Very high	1 Å²	1	8.2 Å²	8.2	0%	0.004	4%	0.037	C	C	.	.	H	α-helix	trans	-62.7	-34.9	174.3	-81.3	-64.8	0	0	0	112.2	H208 A220 K271 I274 A275 S311 S312 N319	H208-F315 HydrophobicContact CB-CE1 4.09Å; H208-F315 HydrophobicContact CB-CZ 4.01Å; H208-F315 AromaticContact CE1-CE2 3.8Å; H208-F315 AromaticContact CE1-CZ 3.92Å; H208-F315 AromaticContact CG-CZ 3.7Å; H208-F315 AromaticContact ND1-CE1 3.81Å; H208-F315 AromaticContact ND1-CE2 3.51Å; H208-F315 AromaticContact ND1-CZ 3.23Å; H208-F315 WeakPolarHBondContact ND1-CZ 3.49Å; A220-F315 HydrophobicContact CB-CD2 3.75Å; A220-F315 HydrophobicContact CB-CE2 3.61Å; K271-F315 HydrophobicContact CB-CE1 4.44Å; I274-F315 HydrophobicContact CB-CD1 4.5Å; I274-F315 HydrophobicContact CB-CE1 4.02Å; I274-F315 HydrophobicContact CB-CE2 4.5Å; I274-F315 HydrophobicContact CB-CZ 4.01Å; I274-F315 HydrophobicContact CG2-CD1 4.2Å; I274-F315 HydrophobicContact CG2-CD2 3.91Å; I274-F315 HydrophobicContact CG2-CE1 3.9Å; I274-F315 HydrophobicContact CG2-CE2 3.57Å; I274-F315 HydrophobicContact CG2-CG 4.2Å; I274-F315 HydrophobicContact CG2-CZ 3.57Å; A275-F315 HydrophobicContact CB-CZ 4.25Å; S311-F315 WeakPolarHBondContact O-CD2 3.29Å; S311-F315 PolarHBondContact O-N 3.31Å; S312-F315 PolarHBondContact O-N 3.35Å; F315-N319 PolarHBondContact O-N 3.01Å
316	C	95.9	Very high	94.5	Very high	3 Å²	3	10.6 Å²	10.6	2%	0.02	6%	0.063	C	C	.	.	H	α-helix	trans	-69	-40.9	174.1	-167.6	0	0	0	0	112.4	S312 G313 L314 A318 N319 V320 L424 M425	S312-C316 PolarHBondContact O-N 2.95Å; G313-C316 PolarHBondContact O-N 2.88Å; G313-C316 VanDerWaalsContact O-N 3.17Å; L314-C316 VanDerWaalsContact C-N 3.27Å; L314-C316 PolarHBondContact O-N 2.94Å; C316-A318 VanDerWaalsContact C-N 3.32Å; C316-A318 PolarHBondContact O-N 3.44Å; C316-N319 WeakPolarHBondContact O-CB 3.48Å; C316-N319 PolarHBondContact O-N 3.35Å; C316-N319 VanDerWaalsContact O-N 3.12Å; C316-V320 WeakPolarHBondContact O-CG2 3.38Å; C316-V320 PolarHBondContact O-N 2.85Å; C316-L424 HydrophobicContact CB-CD2 3.52Å; C316-L424 VanDerWaalsContact SG-CD1 3.51Å; C316-L424 WeakPolarHBondContact SG-CD2 3.23Å; C316-M425 HydrophobicContact CB-SD 4.41Å
317	L	95.5	Very high	94.2	Very high	0 Å²	0	11.6 Å²	11.6	0%	0	7%	0.07	C	C	.	.	H	α-helix	trans	-60.1	-43.5	174	-76.2	173.8	0	0	0	112	G313 L314 N319 V320 S321 W346 W347 L350 M425	G313-L317 PolarHBondContact O-N 3.27Å; L314-L317 HydrophobicContact CD2-CD1 4.42Å; L314-L317 PolarHBondContact O-N 3.05Å; L317-N319 VanDerWaalsContact C-N 3.28Å; L317-N319 PolarHBondContact O-N 3.21Å; L317-V320 PolarHBondContact O-N 3.33Å; L317-S321 PolarHBondContact O-N 2.82Å; L317-W346 HydrophobicContact CD2-CB 4.23Å; L317-W347 HydrophobicContact CB-CD2 3.98Å; L317-W347 HydrophobicContact CB-CE3 4.19Å; L317-W347 HydrophobicContact CB-CH2 3.79Å; L317-W347 HydrophobicContact CB-CZ2 3.56Å; L317-W347 HydrophobicContact CB-CZ3 4.08Å; L317-W347 HydrophobicContact CD1-CB 4.4Å; L317-W347 HydrophobicContact CD1-CD2 3.74Å; L317-W347 HydrophobicContact CD1-CE3 3.87Å; L317-W347 HydrophobicContact CD1-CG 3.95Å; L317-W347 HydrophobicContact CD1-CZ3 4.42Å; L317-W347 HydrophobicContact CD2-CD2 4.43Å; L317-W347 HydrophobicContact CD2-CG 4.31Å; L317-W347 HydrophobicContact CG-CD2 4.28Å; L317-W347 WeakPolarHBondContact O-CZ2 3.49Å; L317-L350 HydrophobicContact CD1-CB 4.23Å; L317-L350 HydrophobicContact CD1-CD1 3.76Å; L317-L350 HydrophobicContact CD1-CG 4.47Å; L317-L350 HydrophobicContact CG-CD1 4.37Å; L317-M425 HydrophobicContact CD1-CE 3.79Å; L317-M425 HydrophobicContact CD2-CE 3.58Å; L317-M425 HydrophobicContact CD2-CG 4.12Å; L317-M425 HydrophobicContact CD2-SD 3.66Å; L317-M425 HydrophobicContact CG-CE 3.34Å; L317-M425 HydrophobicContact CG-SD 3.83Å
318	A	95.7	Very high	94	Very high	2 Å²	2	13.2 Å²	13.2	2%	0.017	8%	0.076	C	C	.	.	H	α-helix	trans	-59.2	-41.7	173.6	0	0	0	0	0	111.1	K271 I274 L314 C316 S321 Y322	K271-A318 HydrophobicContact CG-CB 4.36Å; I274-A318 HydrophobicContact CD1-CB 3.81Å; L314-A318 PolarHBondContact O-N 3.18Å; C316-A318 VanDerWaalsContact C-N 3.32Å; C316-A318 PolarHBondContact O-N 3.44Å; A318-S321 PolarHBondContact O-N 3.28Å; A318-S321 PolarHBondContact O-OG 3.29Å; A318-Y322 WeakPolarHBondContact O-CB 3.43Å; A318-Y322 PolarHBondContact O-N 3.21Å
319	N	95	Very high	93.9	Very high	2 Å²	2	14.4 Å²	14.4	1%	0.011	9%	0.085	C	C	.	.	H	α-helix	trans	-64.9	-42.3	174.9	-179.8	60.5	0	0	0	113.2	V213 F315 C316 L317 S321 Y322 E323	V213-N319 HydrophobicContact CB-CB 4.26Å; V213-N319 HydrophobicContact CG1-CB 3.66Å; V213-N319 HydrophobicContact CG2-CB 3.59Å; V213-N319 VanDerWaalsContact CG2-ND2 3.34Å; V213-N319 WeakPolarHBondContact CG2-ND2 3.33Å; V213-N319 WeakPolarHBondContact CG2-OD1 3.39Å; F315-N319 PolarHBondContact O-N 3.01Å; C316-N319 WeakPolarHBondContact O-CB 3.48Å; C316-N319 PolarHBondContact O-N 3.35Å; C316-N319 VanDerWaalsContact O-N 3.12Å; L317-N319 VanDerWaalsContact C-N 3.28Å; L317-N319 PolarHBondContact O-N 3.21Å; N319-S321 PolarHBondContact O-N 2.89Å; N319-Y322 CarbonylContact O-C 3.5Å; N319-Y322 WeakPolarHBondContact O-CA 3.49Å; N319-Y322 WeakPolarHBondContact O-CB 3.36Å; N319-Y322 PolarHBondContact O-N 3.17Å; N319-E323 PolarHBondContact ND2-OE1 3.01Å; N319-E323 PolarHBondContact O-N 3.33Å
320	V	93.9	Very high	93.7	Very high	2 Å²	2	14.4 Å²	14.4	1%	0.012	9%	0.085	C	C	.	.	H	α-helix	trans	-60.7	-36.2	178.2	166.5	0	0	0	0	110.9	C316 L317 R324 M343 E421	C316-V320 WeakPolarHBondContact O-CG2 3.38Å; C316-V320 PolarHBondContact O-N 2.85Å; L317-V320 PolarHBondContact O-N 3.33Å; V320-R324 VanDerWaalsContact CG1-CZ 3.47Å; V320-R324 PolarHBondContact O-NH1 3.41Å; V320-R324 VanDerWaalsContact O-NH1 3.16Å; V320-M343 HydrophobicContact CG1-CE 4.42Å; V320-E421 HydrophobicContact CG2-CB 4.31Å; V320-E421 HydrophobicContact CG2-CG 3.98Å
321	S	92.7	Very high	93.4	Very high	2 Å²	2	19.3 Å²	19.3	1%	0.014	11%	0.11	C	C	.	.	H	α-helix	trans	-68.4	-39.9	169.9	70.3	0	0	0	0	112.9	L317 A318 N319 R324 L325 N333	L317-S321 PolarHBondContact O-N 2.82Å; A318-S321 PolarHBondContact O-N 3.28Å; A318-S321 PolarHBondContact O-OG 3.29Å; N319-S321 PolarHBondContact O-N 2.89Å; S321-R324 PolarHBondContact O-N 2.9Å; S321-L325 PolarHBondContact O-N 3.02Å; S321-N333 PolarHBondContact OG-ND2 3.24Å
322	Y	92.6	Very high	93.2	Very high	46 Å²	46	21.7 Å²	21.7	18%	0.18	12%	0.122	C	C	.	.	H	α-helix	trans	-66	-41.7	179	178.9	-101.9	0	0	0	112.9	Y132 A318 N319 R324 G326 R328	Y132-Y322 HydrophobicContact CD1-CE1 4.21Å; Y132-Y322 HydrophobicContact CD2-CE1 4.33Å; Y132-Y322 HydrophobicContact CE1-CE1 4.07Å; Y132-Y322 HydrophobicContact CE2-CE1 4.2Å; Y132-Y322 HydrophobicContact CG-CE1 4.34Å; A318-Y322 WeakPolarHBondContact O-CB 3.43Å; A318-Y322 PolarHBondContact O-N 3.21Å; N319-Y322 CarbonylContact O-C 3.5Å; N319-Y322 WeakPolarHBondContact O-CA 3.49Å; N319-Y322 WeakPolarHBondContact O-CB 3.36Å; N319-Y322 PolarHBondContact O-N 3.17Å; Y322-R324 PolarHBondContact O-N 3.15Å; Y322-G326 VanDerWaalsContact O-CA 3.27Å; Y322-G326 WeakPolarHBondContact O-CA 3.12Å; Y322-G326 PolarHBondContact O-N 3.22Å; Y322-R328 HydrophobicContact CD2-CG 3.71Å; Y322-R328 HydrophobicContact CE2-CG 3.86Å
323	E	90.4	Very high	92.9	Very high	47 Å²	47	21.7 Å²	21.7	22%	0.22	12%	0.122	C	C	.	.	H	α-helix	trans	-60.3	-26.3	177.9	-76.7	-176.7	-168.1	0	0	112.8	M78 N319 R420	M78-E323 HydrophobicContact CG-CG 4.25Å; M78-E323 WeakPolarHBondContact CG-OE1 3.16Å; N319-E323 PolarHBondContact ND2-OE1 3.01Å; N319-E323 PolarHBondContact O-N 3.33Å; E323-R420 IonicContact OE2-NH2 3.91Å
324	R	89.4	Confident	92.6	Very high	30 Å²	30	24.8 Å²	24.8	11%	0.113	14%	0.136	C	C	.	.	H	α-helix	trans	-93.4	-49.2	179.5	-59.8	-171.5	-165.4	100.4	-0.3	112.4	V320 S321 Y322 M340 S413 S415 E421	V320-R324 VanDerWaalsContact CG1-CZ 3.47Å; V320-R324 PolarHBondContact O-NH1 3.41Å; V320-R324 VanDerWaalsContact O-NH1 3.16Å; S321-R324 PolarHBondContact O-N 2.9Å; Y322-R324 PolarHBondContact O-N 3.15Å; R324-M340 PolarHBondContact NH1-SD 2.96Å; R324-S413 WeakPolarHBondContact O-CB 3.23Å; R324-S413 PolarHBondContact O-OG 3.14Å; R324-S415 WeakPolarHBondContact CD-O 3.34Å; R324-S415 WeakPolarHBondContact CD-OG 3.28Å; R324-S415 PolarHBondContact NE-O 3.16Å; R324-S415 PolarHBondContact NE-OG 3.17Å; R324-S415 VanDerWaalsContact NE-OG 3.07Å; R324-E421 IonicContact CZ-OE2 3.88Å; R324-E421 IonicContact NH2-OE2 2.73Å; R324-E421 PolarHBondContact NH2-OE2 3.09Å
325	L	89.4	Confident	92.2	Very high	26 Å²	26	24.7 Å²	24.7	14%	0.136	14%	0.136	C	C	.	.	H	α-helix	trans	-91	-13.8	-172.2	-60.2	178.9	0	0	0	113.2	S321 S327 N333 L336 V411	S321-L325 PolarHBondContact O-N 3.02Å; L325-S327 PolarHBondContact O-N 3.38Å; L325-S327 VanDerWaalsContact O-N 3.12Å; L325-N333 HydrophobicContact CD1-CB 3.89Å; L325-N333 VanDerWaalsContact CD1-CG 3.49Å; L325-N333 WeakPolarHBondContact CD1-OD1 3.34Å; L325-L336 HydrophobicContact CD1-CD2 3.97Å; L325-V411 HydrophobicContact CD2-CB 4.15Å; L325-V411 HydrophobicContact CD2-CG1 3.53Å; L325-V411 HydrophobicContact CD2-CG2 4.46Å
326	G	88.1	Confident	91.9	Very high	55 Å²	55	25 Å²	25	57%	0.567	14%	0.137	S	C	*	.	S	Bend	trans	68.7	4.5	-179.6	0	0	0	0	0	114.6	Y322	Y322-G326 VanDerWaalsContact O-CA 3.27Å; Y322-G326 WeakPolarHBondContact O-CA 3.12Å; Y322-G326 PolarHBondContact O-N 3.22Å
327	S	90.6	Very high	91.8	Very high	20 Å²	20	27.9 Å²	27.9	14%	0.14	15%	0.152	C	C	.	.			trans	-132.1	148.1	-175.6	100.4	0	0	0	0	112	L325 I332 N333	L325-S327 PolarHBondContact O-N 3.38Å; L325-S327 VanDerWaalsContact O-N 3.12Å; S327-I332 VanDerWaalsContact OG-CB 3.27Å; S327-I332 WeakPolarHBondContact OG-CB 3.46Å; S327-I332 WeakPolarHBondContact OG-CD1 3.47Å; S327-I332 WeakPolarHBondContact OG-CG2 3.31Å; S327-N333 PolarHBondContact O-ND2 2.76Å; S327-N333 VanDerWaalsContact O-ND2 3.11Å; S327-N333 PolarHBondContact O-OD1 2.66Å; S327-N333 PolarHBondContact OG-OD1 3.27Å
328	R	91.4	Very high	91.5	Very high	35 Å²	35	33 Å²	33	13%	0.132	18%	0.179	C	C	.	.			trans	-92.6	-9	177.7	-57.1	-177	-60.3	-156.6	0.8	112.9	Q133 V209 E210 L270 Y322	Q133-R328 VanDerWaalsContact CD-CZ 3.41Å; Q133-R328 VanDerWaalsContact CD-NH1 3.28Å; Q133-R328 VanDerWaalsContact NE2-CZ 3.3Å; V209-R328 PolarHBondContact O-NH1 3.28Å; E210-R328 IonicContact OE1-CZ 3.71Å; E210-R328 IonicContact OE1-NH1 3.48Å; E210-R328 PolarHBondContact OE1-NH1 3.14Å; E210-R328 IonicContact OE1-NH2 2.82Å; E210-R328 PolarHBondContact OE1-NH2 3.11Å; E210-R328 IonicContact OE2-NH1 3.23Å; L270-R328 WeakPolarHBondContact CB-O 3.47Å; L270-R328 PolarHBondContact N-O 3.13Å; Y322-R328 HydrophobicContact CD2-CG 3.71Å; Y322-R328 HydrophobicContact CE2-CG 3.86Å
329	S	93.8	Very high	91	Very high	26 Å²	26	36.2 Å²	36.2	18%	0.182	19%	0.193	C	C	.	.	B	Isolated β-bridge	trans	-75.5	135.5	-171.5	77.1	0	0	0	0	111.7	L331 I332 N333	S329-L331 PolarHBondContact O-N 3.25Å; S329-I332 PolarHBondContact O-N 2.97Å; S329-I332 WeakPolarHBondContact OG-CB 3.35Å; S329-I332 WeakPolarHBondContact OG-CD1 3.4Å; S329-I332 VanDerWaalsContact OG-CG1 3.25Å; S329-I332 WeakPolarHBondContact OG-CG1 3.35Å; S329-I332 PolarHBondContact OG-N 3.48Å; S329-N333 WeakPolarHBondContact O-CB 3.38Å; S329-N333 PolarHBondContact O-N 3.35Å
330	M	92.4	Very high	90.7	Very high	3 Å²	3	36.2 Å²	36.2	2%	0.015	19%	0.193	C	C	.	.	T	Hydrogen-bonded Turn	trans	-59.4	-26.8	172.8	-71.8	-69.7	-67.7	0	0	112.2	T268 L270 K334 F401	T268-M330 VanDerWaalsContact O-CB 3.25Å; T268-M330 WeakPolarHBondContact O-CB 3.45Å; T268-M330 WeakPolarHBondContact O-CG 3.48Å; T268-M330 PolarHBondContact O-N 3.47Å; L270-M330 HydrophobicContact CB-SD 4.46Å; L270-M330 HydrophobicContact CD1-SD 4.33Å; L270-M330 HydrophobicContact CD2-CE 4.43Å; L270-M330 HydrophobicContact CD2-CG 4.41Å; L270-M330 HydrophobicContact CD2-SD 3.08Å; L270-M330 WeakPolarHBondContact CD2-SD 3.13Å; L270-M330 HydrophobicContact CG-CG 4.12Å; L270-M330 HydrophobicContact CG-SD 3.35Å; L270-M330 WeakPolarHBondContact CG-SD 3.37Å; M330-K334 WeakPolarHBondContact O-CG 3.31Å; M330-F401 HydrophobicContact CE-CB 3.33Å; M330-F401 HydrophobicContact CE-CG 4.47Å
331	L	90.6	Very high	90.6	Very high	104 Å²	104	39.8 Å²	39.8	55%	0.545	22%	0.216	S	C	.	.	T	Hydrogen-bonded Turn	trans	-72.9	-36.3	-177.3	-64.9	177	0	0	0	113.2	S329 K334	S329-L331 PolarHBondContact O-N 3.25Å; L331-K334 WeakPolarHBondContact O-CD 3.01Å; L331-K334 WeakPolarHBondContact O-CG 3.23Å
332	I	91.8	Very high	90.5	Very high	50 Å²	50	42.1 Å²	42.1	26%	0.256	23%	0.232	S	C	.	.	T	Hydrogen-bonded Turn	trans	-80.5	-36.9	176.3	-64.8	169.6	0	0	0	109.8	S327 S329 K334 F408 V411	S327-I332 VanDerWaalsContact OG-CB 3.27Å; S327-I332 WeakPolarHBondContact OG-CB 3.46Å; S327-I332 WeakPolarHBondContact OG-CD1 3.47Å; S327-I332 WeakPolarHBondContact OG-CG2 3.31Å; S329-I332 PolarHBondContact O-N 2.97Å; S329-I332 WeakPolarHBondContact OG-CB 3.35Å; S329-I332 WeakPolarHBondContact OG-CD1 3.4Å; S329-I332 VanDerWaalsContact OG-CG1 3.25Å; S329-I332 WeakPolarHBondContact OG-CG1 3.35Å; S329-I332 PolarHBondContact OG-N 3.48Å; I332-K334 PolarHBondContact O-N 3.12Å; I332-F408 HydrophobicContact CG2-CD1 4.24Å; I332-V411 HydrophobicContact CG2-CG2 4.25Å
333	N	90.6	Very high	90.6	Very high	0 Å²	0	39.9 Å²	39.9	0%	0	22%	0.224	C	C	.	.	S	Bend	trans	-83.5	37.9	-174	-62.3	3.3	0	0	0	113.5	L270 S321 L325 S327 S329 L336 S402	L270-N333 HydrophobicContact CD1-CB 3.87Å; L270-N333 WeakPolarHBondContact CD1-ND2 3.16Å; S321-N333 PolarHBondContact OG-ND2 3.24Å; L325-N333 HydrophobicContact CD1-CB 3.89Å; L325-N333 VanDerWaalsContact CD1-CG 3.49Å; L325-N333 WeakPolarHBondContact CD1-OD1 3.34Å; S327-N333 PolarHBondContact O-ND2 2.76Å; S327-N333 VanDerWaalsContact O-ND2 3.11Å; S327-N333 PolarHBondContact O-OD1 2.66Å; S327-N333 PolarHBondContact OG-OD1 3.27Å; S329-N333 WeakPolarHBondContact O-CB 3.38Å; S329-N333 PolarHBondContact O-N 3.35Å; N333-L336 HydrophobicContact CB-CD1 4.4Å; N333-S402 CarbonylContact O-C 3.55Å; N333-S402 VanDerWaalsContact O-CA 3.26Å; N333-S402 WeakPolarHBondContact O-CA 3.38Å
334	K	90	Very high	90.8	Very high	65 Å²	65	38.1 Å²	38.1	28%	0.283	22%	0.216	S	C	.	.			trans	-92.7	150.7	-178.5	-65.3	-174.2	165	169.5	0	113	M330 L331 I332 L336 F401 S402 L407	M330-K334 WeakPolarHBondContact O-CG 3.31Å; L331-K334 WeakPolarHBondContact O-CD 3.01Å; L331-K334 WeakPolarHBondContact O-CG 3.23Å; I332-K334 PolarHBondContact O-N 3.12Å; K334-L336 VanDerWaalsContact C-N 3.33Å; K334-L336 PolarHBondContact O-N 3.26Å; K334-F401 WeakPolarHBondContact CG-O 3.43Å; K334-S402 CarbonylContact C-O 3.45Å; K334-L407 WeakPolarHBondContact O-CD2 3.24Å
335	G	90	Very high	91	Very high	0 Å²	0	41.3 Å²	41.3	0%	0	24%	0.235	C	C	.	.			trans	72.5	18.4	170.7	0	0	0	0	0	115.6	L337 N338 S402 Q403 H404 G405 L407	G335-L337 PolarHBondContact O-N 2.72Å; G335-N338 PolarHBondContact O-N 3.11Å; G335-S402 PolarHBondContact N-O 3.28Å; G335-S402 VanDerWaalsContact N-O 3.17Å; G335-Q403 CarbonylContact C-O 3.16Å; G335-Q403 VanDerWaalsContact CA-O 3.27Å; G335-Q403 WeakPolarHBondContact CA-O 3.48Å; G335-H404 WeakPolarHBondContact CA-O 3.47Å; G335-H404 PolarHBondContact N-O 2.86Å; G335-H404 VanDerWaalsContact N-O 3.08Å; G335-G405 WeakPolarHBondContact CA-O 2.85Å; G335-L407 WeakPolarHBondContact O-CD2 3.46Å
336	L	91	Very high	91.3	Very high	8 Å²	8	41.7 Å²	41.7	4%	0.042	23%	0.234	C	C	.	.	G	3₁₀ helix	trans	-57.5	-17.7	-173.3	-71.4	170	0	0	0	114.6	L325 N333 K334 N338 F339 M340 S402 Q403	L325-L336 HydrophobicContact CD1-CD2 3.97Å; N333-L336 HydrophobicContact CB-CD1 4.4Å; K334-L336 VanDerWaalsContact C-N 3.33Å; K334-L336 PolarHBondContact O-N 3.26Å; L336-N338 PolarHBondContact O-N 3.45Å; L336-F339 PolarHBondContact O-N 3.31Å; L336-F339 VanDerWaalsContact O-N 3.12Å; L336-M340 HydrophobicContact CB-CE 3.75Å; L336-M340 HydrophobicContact CB-CG 4.43Å; L336-M340 HydrophobicContact CD1-CE 3.61Å; L336-M340 HydrophobicContact CD2-CE 3.85Å; L336-M340 HydrophobicContact CG-CE 3.92Å; L336-M340 WeakPolarHBondContact O-CG 3.1Å; L336-M340 PolarHBondContact O-N 3.45Å; L336-S402 PolarHBondContact N-O 3.28Å; L336-Q403 PolarHBondContact N-O 2.93Å
337	L	92.9	Very high	91.7	Very high	63 Å²	63	39.1 Å²	39.1	33%	0.33	21%	0.208	S	C	.	.	G	3₁₀ helix	trans	-58.4	-34.3	173.3	-170.3	144	0	0	0	113.5	G335 F339 T344 Q403	G335-L337 PolarHBondContact O-N 2.72Å; L337-F339 VanDerWaalsContact C-N 3.32Å; L337-F339 PolarHBondContact O-N 3.06Å; L337-T344 HydrophobicContact CB-CG2 4.01Å; L337-T344 HydrophobicContact CG-CG2 4.44Å; L337-Q403 WeakPolarHBondContact CB-O 3.27Å; L337-Q403 PolarHBondContact N-O 3.02Å; L337-Q403 VanDerWaalsContact N-O 3.07Å
338	N	89.1	Confident	91.9	Very high	106 Å²	106	43.2 Å²	43.2	57%	0.567	22%	0.223	S	C	*	.	G	3₁₀ helix	trans	-73.5	-26.4	178.3	-63.7	-22.9	0	0	0	112.5	G335 L336 L407	G335-N338 PolarHBondContact O-N 3.11Å; L336-N338 PolarHBondContact O-N 3.45Å; N338-L407 HydrophobicContact CB-CD1 3.68Å; N338-L407 HydrophobicContact CB-CD2 4.38Å; N338-L407 HydrophobicContact CB-CG 4.21Å
339	F	84.5	Confident	92.1	Very high	70 Å²	70	43.3 Å²	43.3	31%	0.307	23%	0.226	S	C	.	.	T	Hydrogen-bonded Turn	trans	-95.7	-39.7	-176.8	-69.6	-41.1	0	0	0	113.7	L336 L337 L407 F414	L336-F339 PolarHBondContact O-N 3.31Å; L336-F339 VanDerWaalsContact O-N 3.12Å; L337-F339 VanDerWaalsContact C-N 3.32Å; L337-F339 PolarHBondContact O-N 3.06Å; F339-L407 HydrophobicContact CD1-CD1 3.66Å; F339-L407 HydrophobicContact CD1-CD2 4.4Å; F339-L407 HydrophobicContact CD2-CD1 4.01Å; F339-L407 HydrophobicContact CD2-CD2 3.18Å; F339-L407 HydrophobicContact CD2-CG 4.06Å; F339-L407 HydrophobicContact CE1-CD1 3.13Å; F339-L407 HydrophobicContact CE1-CD2 4.25Å; F339-L407 HydrophobicContact CE1-CG 4.09Å; F339-L407 HydrophobicContact CE2-CB 3.78Å; F339-L407 HydrophobicContact CE2-CD1 3.57Å; F339-L407 HydrophobicContact CE2-CD2 3.02Å; F339-L407 HydrophobicContact CE2-CG 3.55Å; F339-L407 HydrophobicContact CG-CD1 4.06Å; F339-L407 HydrophobicContact CG-CD2 3.91Å; F339-L407 HydrophobicContact CZ-CB 3.66Å; F339-L407 HydrophobicContact CZ-CD1 3.06Å; F339-L407 HydrophobicContact CZ-CD2 3.58Å; F339-L407 HydrophobicContact CZ-CG 3.52Å; F339-F414 AromaticContact CD1-CD1 3.74Å; F339-F414 HydrophobicContact CD1-CD1 3.74Å; F339-F414 AromaticContact CD1-CE1 3.74Å; F339-F414 HydrophobicContact CD1-CE1 3.74Å; F339-F414 HydrophobicContact CD2-CD1 4.46Å; F339-F414 HydrophobicContact CD2-CE1 4.23Å; F339-F414 AromaticContact CE1-CD1 3.65Å; F339-F414 HydrophobicContact CE1-CD1 3.65Å; F339-F414 AromaticContact CE1-CE1 3.14Å; F339-F414 HydrophobicContact CE1-CE1 3.14Å; F339-F414 AromaticContact CE1-CZ 3.78Å; F339-F414 HydrophobicContact CE1-CZ 3.78Å; F339-F414 HydrophobicContact CE2-CD1 4.34Å; F339-F414 AromaticContact CE2-CE1 3.68Å; F339-F414 HydrophobicContact CE2-CE1 3.68Å; F339-F414 HydrophobicContact CG-CD1 4.18Å; F339-F414 HydrophobicContact CG-CE1 4.26Å; F339-F414 AromaticContact CZ-CD1 3.99Å; F339-F414 HydrophobicContact CZ-CD1 3.99Å; F339-F414 AromaticContact CZ-CE1 3.13Å; F339-F414 HydrophobicContact CZ-CE1 3.13Å; F339-F414 AromaticContact CZ-CZ 3.79Å; F339-F414 HydrophobicContact CZ-CZ 3.79Å
340	M	89.8	Confident	92.3	Very high	2 Å²	2	42 Å²	42	1%	0.01	22%	0.217	C	C	.	.			trans	-139.6	66.4	-172.4	56.7	167.5	-173.6	0	0	112.4	R324 L336 S342 M343 T344	R324-M340 PolarHBondContact NH1-SD 2.96Å; L336-M340 HydrophobicContact CB-CE 3.75Å; L336-M340 HydrophobicContact CB-CG 4.43Å; L336-M340 HydrophobicContact CD1-CE 3.61Å; L336-M340 HydrophobicContact CD2-CE 3.85Å; L336-M340 HydrophobicContact CG-CE 3.92Å; L336-M340 WeakPolarHBondContact O-CG 3.1Å; L336-M340 PolarHBondContact O-N 3.45Å; M340-S342 VanDerWaalsContact C-N 3.3Å; M340-S342 PolarHBondContact O-N 3.35Å; M340-M343 HydrophobicContact CB-CB 4.02Å; M340-M343 HydrophobicContact CB-CG 4.29Å; M340-M343 HydrophobicContact CE-CB 4.29Å; M340-M343 HydrophobicContact CG-CB 3.91Å; M340-M343 WeakPolarHBondContact O-CB 3.28Å; M340-M343 PolarHBondContact O-N 3Å; M340-M343 HydrophobicContact SD-CB 3.48Å; M340-M343 WeakPolarHBondContact SD-CB 3.47Å; M340-M343 HydrophobicContact SD-CG 3.82Å; M340-T344 WeakPolarHBondContact O-CG2 3.49Å; M340-T344 PolarHBondContact O-N 3.15Å
341	P	90.8	Very high	92.4	Very high	78 Å²	78	42 Å²	42	51%	0.506	22%	0.218	S	C	.	.	H	α-helix	trans	-59	-38.2	-172.1	23.4	-34.3	0	0	0	113.1	M343 T344 L345	P341-M343 VanDerWaalsContact C-N 3.34Å; P341-M343 PolarHBondContact O-N 3.11Å; P341-T344 PolarHBondContact O-N 2.97Å; P341-T344 VanDerWaalsContact O-N 3.1Å; P341-T344 PolarHBondContact O-OG1 3.2Å; P341-L345 PolarHBondContact O-N 3.44Å
342	S	92.3	Very high	92.7	Very high	50 Å²	50	38.2 Å²	38.2	35%	0.35	20%	0.2	S	C	.	.	H	α-helix	trans	-62.4	-37.4	175.5	42.3	0	0	0	0	112.9	M340 T344 Y422	M340-S342 VanDerWaalsContact C-N 3.3Å; M340-S342 PolarHBondContact O-N 3.35Å; S342-T344 VanDerWaalsContact C-N 3.34Å; S342-Y422 WeakPolarHBondContact CB-OH 3.11Å; S342-Y422 PolarHBondContact OG-OH 3.35Å
343	M	93.6	Very high	92.8	Very high	0 Å²	0	35.9 Å²	35.9	0%	0	19%	0.187	C	C	.	.	H	α-helix	trans	-71.5	-31.3	173.1	-73.3	-63.4	-175.8	0	0	112.1	V320 M340 P341 L345 W346 W347 E421 Y422	V320-M343 HydrophobicContact CG1-CE 4.42Å; M340-M343 HydrophobicContact CB-CB 4.02Å; M340-M343 HydrophobicContact CB-CG 4.29Å; M340-M343 HydrophobicContact CE-CB 4.29Å; M340-M343 HydrophobicContact CG-CB 3.91Å; M340-M343 WeakPolarHBondContact O-CB 3.28Å; M340-M343 PolarHBondContact O-N 3Å; M340-M343 HydrophobicContact SD-CB 3.48Å; M340-M343 WeakPolarHBondContact SD-CB 3.47Å; M340-M343 HydrophobicContact SD-CG 3.82Å; P341-M343 VanDerWaalsContact C-N 3.34Å; P341-M343 PolarHBondContact O-N 3.11Å; M343-L345 VanDerWaalsContact C-N 3.25Å; M343-L345 PolarHBondContact O-N 3.17Å; M343-W346 WeakPolarHBondContact O-CB 3.41Å; M343-W346 PolarHBondContact O-N 3.46Å; M343-W346 VanDerWaalsContact O-N 3.11Å; M343-W347 PolarHBondContact O-N 3.2Å; M343-E421 HydrophobicContact CE-CB 3.35Å; M343-E421 HydrophobicContact CE-CG 4.4Å; M343-E421 WeakPolarHBondContact CE-OE2 3.26Å; M343-Y422 HydrophobicContact CE-CD1 3.76Å; M343-Y422 HydrophobicContact CE-CD2 4.29Å; M343-Y422 HydrophobicContact CE-CE1 3.49Å; M343-Y422 VanDerWaalsContact CE-CE1 3.49Å; M343-Y422 HydrophobicContact CE-CE2 4.03Å; M343-Y422 HydrophobicContact CE-CG 4.16Å; M343-Y422 HydrophobicContact CG-CE1 3.93Å; M343-Y422 HydrophobicContact SD-CD1 3.92Å; M343-Y422 HydrophobicContact SD-CE1 3.52Å; M343-Y422 VanDerWaalsContact SD-CE1 3.52Å
344	T	94.3	Very high	93.1	Very high	9 Å²	9	36 Å²	36	6%	0.055	19%	0.189	C	C	.	.	H	α-helix	trans	-68	-27.8	178.4	73.8	0	0	0	0	112.9	L337 M340 P341 S342 W346 W347 F348 Q403	L337-T344 HydrophobicContact CB-CG2 4.01Å; L337-T344 HydrophobicContact CG-CG2 4.44Å; M340-T344 WeakPolarHBondContact O-CG2 3.49Å; M340-T344 PolarHBondContact O-N 3.15Å; P341-T344 PolarHBondContact O-N 2.97Å; P341-T344 VanDerWaalsContact O-N 3.1Å; P341-T344 PolarHBondContact O-OG1 3.2Å; S342-T344 VanDerWaalsContact C-N 3.34Å; T344-W346 VanDerWaalsContact C-N 3.34Å; T344-W347 WeakPolarHBondContact O-CB 3.46Å; T344-W347 PolarHBondContact O-N 3.07Å; T344-F348 PolarHBondContact O-N 3.2Å; T344-Q403 HydrophobicContact CG2-CG 4.48Å
345	L	94.6	Very high	93.3	Very high	97 Å²	97	35.1 Å²	35.1	51%	0.508	19%	0.186	S	C	.	.	H	α-helix	trans	-62.5	-42	170.4	-179	135.5	0	0	0	110.9	P341 M343 F348 L349	P341-L345 PolarHBondContact O-N 3.44Å; M343-L345 VanDerWaalsContact C-N 3.25Å; M343-L345 PolarHBondContact O-N 3.17Å; L345-F348 WeakPolarHBondContact O-CB 3.46Å; L345-F348 PolarHBondContact O-N 3.07Å; L345-L349 HydrophobicContact CD2-CD1 3.63Å; L345-L349 HydrophobicContact CD2-CG 4.35Å; L345-L349 HydrophobicContact CG-CD1 4.38Å; L345-L349 WeakPolarHBondContact O-CB 3.4Å; L345-L349 WeakPolarHBondContact O-CG 3.33Å; L345-L349 PolarHBondContact O-N 3.38Å
346	W	95.3	Very high	93.5	Very high	34 Å²	34	35.6 Å²	35.6	13%	0.129	19%	0.19	C	C	.	.	H	α-helix	trans	-67.4	-36.7	175.2	-64.9	107.5	0	0	0	113	L317 M343 T344 F348 L349 L350 Y422 M425 L426 W429	L317-W346 HydrophobicContact CD2-CB 4.23Å; M343-W346 WeakPolarHBondContact O-CB 3.41Å; M343-W346 PolarHBondContact O-N 3.46Å; M343-W346 VanDerWaalsContact O-N 3.11Å; T344-W346 VanDerWaalsContact C-N 3.34Å; W346-F348 VanDerWaalsContact C-N 3.33Å; W346-L349 HydrophobicContact CE3-CD1 3.96Å; W346-L349 HydrophobicContact CZ3-CD1 4Å; W346-L349 PolarHBondContact O-N 3.43Å; W346-L350 PolarHBondContact O-N 3.34Å; W346-Y422 AromaticContact CD1-CD1 3.81Å; W346-Y422 AromaticContact NE1-CD1 3.45Å; W346-M425 HydrophobicContact CB-CB 4.2Å; W346-M425 HydrophobicContact CB-CG 4.15Å; W346-M425 HydrophobicContact CD2-CB 3.69Å; W346-M425 HydrophobicContact CD2-CG 4.5Å; W346-M425 HydrophobicContact CE3-CB 3.89Å; W346-M425 HydrophobicContact CG-CB 3.83Å; W346-M425 HydrophobicContact CG-CG 4.12Å; W346-L426 HydrophobicContact CH2-CB 4.09Å; W346-L426 HydrophobicContact CH2-CD1 3.68Å; W346-L426 HydrophobicContact CZ2-CD1 4.4Å; W346-W429 HydrophobicContact CE3-CB 4.44Å; W346-W429 HydrophobicContact CZ3-CB 3.96Å; W346-W429 HydrophobicContact CZ3-CD2 4.26Å; W346-W429 HydrophobicContact CZ3-CE3 4.4Å; W346-W429 HydrophobicContact CZ3-CG 4.11Å
347	W	95.7	Very high	93.6	Very high	1 Å²	1	36.6 Å²	36.6	0%	0.004	20%	0.199	C	C	.	.	H	α-helix	trans	-57.7	-46.9	169.7	-84.1	101.3	0	0	0	111.6	L270 L317 M343 T344 S351 L398 Y399 Q403	L270-W347 HydrophobicContact CD2-CH2 4.18Å; L317-W347 HydrophobicContact CB-CD2 3.98Å; L317-W347 HydrophobicContact CB-CE3 4.19Å; L317-W347 HydrophobicContact CB-CH2 3.79Å; L317-W347 HydrophobicContact CB-CZ2 3.56Å; L317-W347 HydrophobicContact CB-CZ3 4.08Å; L317-W347 HydrophobicContact CD1-CB 4.4Å; L317-W347 HydrophobicContact CD1-CD2 3.74Å; L317-W347 HydrophobicContact CD1-CE3 3.87Å; L317-W347 HydrophobicContact CD1-CG 3.95Å; L317-W347 HydrophobicContact CD1-CZ3 4.42Å; L317-W347 HydrophobicContact CD2-CD2 4.43Å; L317-W347 HydrophobicContact CD2-CG 4.31Å; L317-W347 HydrophobicContact CG-CD2 4.28Å; L317-W347 WeakPolarHBondContact O-CZ2 3.49Å; M343-W347 PolarHBondContact O-N 3.2Å; T344-W347 WeakPolarHBondContact O-CB 3.46Å; T344-W347 PolarHBondContact O-N 3.07Å; W347-S351 WeakPolarHBondContact O-CB 3.1Å; W347-S351 PolarHBondContact O-N 2.95Å; W347-S351 PolarHBondContact O-OG 3.44Å; W347-L398 HydrophobicContact CE3-CD2 3.68Å; W347-L398 HydrophobicContact CZ3-CD1 4.44Å; W347-L398 HydrophobicContact CZ3-CD2 3.49Å; W347-L398 VanDerWaalsContact CZ3-CD2 3.49Å; W347-L398 HydrophobicContact CZ3-CG 4.27Å; W347-Y399 HydrophobicContact CB-CD2 4.1Å; W347-Y399 HydrophobicContact CB-CE2 4.08Å; W347-Q403 HydrophobicContact CB-CG 4.22Å; W347-Q403 VanDerWaalsContact CD1-NE2 3.26Å; W347-Q403 HydrophobicContact CG-CG 4.41Å; W347-Q403 VanDerWaalsContact CG-NE2 3.29Å
348	F	95.9	Very high	93.4	Very high	106 Å²	106	38.5 Å²	38.5	47%	0.465	22%	0.215	S	C	.	.	H	α-helix	trans	-60.1	-52.3	177.8	178	-103.4	0	0	0	110.9	T344 L345 W346 L350 S351 S352 Y399	T344-F348 PolarHBondContact O-N 3.2Å; L345-F348 WeakPolarHBondContact O-CB 3.46Å; L345-F348 PolarHBondContact O-N 3.07Å; W346-F348 VanDerWaalsContact C-N 3.33Å; F348-L350 PolarHBondContact O-N 3.33Å; F348-S351 WeakPolarHBondContact CA-OG 3.06Å; F348-S351 PolarHBondContact O-N 3.04Å; F348-S351 PolarHBondContact O-OG 3.04Å; F348-S352 WeakPolarHBondContact O-CB 3.28Å; F348-S352 PolarHBondContact O-N 3.36Å; F348-S352 PolarHBondContact O-OG 2.97Å; F348-Y399 HydrophobicContact CB-CD2 4.46Å; F348-Y399 HydrophobicContact CB-CE2 3.68Å; F348-Y399 HydrophobicContact CD2-CE1 4.41Å; F348-Y399 HydrophobicContact CD2-CE2 4.38Å
349	L	96	Very high	93.3	Very high	37 Å²	37	38.2 Å²	38.2	19%	0.194	22%	0.219	C	C	.	.	H	α-helix	trans	-60.1	-39.2	-177.3	-74.2	179.1	0	0	0	114.3	L345 W346 S352 A353 W429	L345-L349 HydrophobicContact CD2-CD1 3.63Å; L345-L349 HydrophobicContact CD2-CG 4.35Å; L345-L349 HydrophobicContact CG-CD1 4.38Å; L345-L349 WeakPolarHBondContact O-CB 3.4Å; L345-L349 WeakPolarHBondContact O-CG 3.33Å; L345-L349 PolarHBondContact O-N 3.38Å; W346-L349 HydrophobicContact CE3-CD1 3.96Å; W346-L349 HydrophobicContact CZ3-CD1 4Å; W346-L349 PolarHBondContact O-N 3.43Å; L349-S352 PolarHBondContact O-OG 3.48Å; L349-A353 PolarHBondContact O-N 3.16Å; L349-W429 HydrophobicContact CD1-CD2 4.4Å; L349-W429 HydrophobicContact CD1-CZ2 4.21Å; L349-W429 HydrophobicContact CD2-CZ2 4.04Å
350	L	96.3	Very high	93.7	Very high	0 Å²	0	35.3 Å²	35.3	0%	0	21%	0.207	C	C	.	.	H	α-helix	trans	-80.9	-31.7	175.6	-73.6	-175.6	0	0	0	112.8	G313 L314 L317 W346 F348 S352 A353 N354 M425 W429	G313-L350 VanDerWaalsContact C-CD1 3.49Å; L314-L350 HydrophobicContact CD2-CB 3.91Å; L314-L350 HydrophobicContact CG-CB 4.46Å; L317-L350 HydrophobicContact CD1-CB 4.23Å; L317-L350 HydrophobicContact CD1-CD1 3.76Å; L317-L350 HydrophobicContact CD1-CG 4.47Å; L317-L350 HydrophobicContact CG-CD1 4.37Å; W346-L350 PolarHBondContact O-N 3.34Å; F348-L350 PolarHBondContact O-N 3.33Å; L350-S352 VanDerWaalsContact C-N 3.35Å; L350-A353 PolarHBondContact O-N 3.28Å; L350-N354 PolarHBondContact O-N 3.48Å; L350-M425 HydrophobicContact CD1-CE 3.11Å; L350-M425 HydrophobicContact CG-CE 4.2Å; L350-W429 HydrophobicContact CD2-CB 4.44Å
351	S	96.2	Very high	93.9	Very high	3 Å²	3	35.3 Å²	35.3	2%	0.021	21%	0.207	C	C	.	.	H	α-helix	trans	-66	-38.4	173.7	70.3	0	0	0	0	111.7	W347 F348 N354 M355	W347-S351 WeakPolarHBondContact O-CB 3.1Å; W347-S351 PolarHBondContact O-N 2.95Å; W347-S351 PolarHBondContact O-OG 3.44Å; F348-S351 WeakPolarHBondContact CA-OG 3.06Å; F348-S351 PolarHBondContact O-N 3.04Å; F348-S351 PolarHBondContact O-OG 3.04Å; S351-N354 WeakPolarHBondContact O-CB 3.24Å; S351-N354 PolarHBondContact O-N 3.31Å; S351-M355 WeakPolarHBondContact O-CG 3.48Å; S351-M355 PolarHBondContact O-N 2.91Å
352	S	95.5	Very high	94.1	Very high	24 Å²	24	31.6 Å²	31.6	17%	0.168	18%	0.183	C	C	.	.	H	α-helix	trans	-68.5	-36.3	175	66.2	0	0	0	0	111.9	F348 L349 L350 N354 M355 A356 A357	F348-S352 WeakPolarHBondContact O-CB 3.28Å; F348-S352 PolarHBondContact O-N 3.36Å; F348-S352 PolarHBondContact O-OG 2.97Å; L349-S352 PolarHBondContact O-OG 3.48Å; L350-S352 VanDerWaalsContact C-N 3.35Å; S352-N354 VanDerWaalsContact C-N 3.32Å; S352-N354 PolarHBondContact O-N 3.27Å; S352-M355 PolarHBondContact O-N 3.09Å; S352-A356 PolarHBondContact O-N 2.96Å; S352-A357 WeakPolarHBondContact O-CB 3.28Å; S352-A357 PolarHBondContact O-N 2.98Å
353	A	95.4	Very high	94.2	Very high	0 Å²	0	31.8 Å²	31.8	0%	0	18%	0.18	C	C	.	.	H	α-helix	trans	-61.7	-40.1	169.8	0	0	0	0	0	111.8	L349 L350 M355 A356 T360 N362 L432	L349-A353 PolarHBondContact O-N 3.16Å; L350-A353 PolarHBondContact O-N 3.28Å; A353-M355 VanDerWaalsContact C-N 3.3Å; A353-M355 PolarHBondContact O-N 3.32Å; A353-A356 WeakPolarHBondContact O-CA 3.21Å; A353-A356 PolarHBondContact O-N 3.15Å; A353-T360 HydrophobicContact CB-CG2 4.04Å; A353-N362 PolarHBondContact O-ND2 2.81Å; A353-L432 HydrophobicContact CB-CD1 4.12Å; A353-L432 HydrophobicContact CB-CD2 3.98Å
354	N	95.7	Very high	94.3	Very high	4 Å²	4	33.2 Å²	33.2	2%	0.021	19%	0.187	C	C	.	.	H	α-helix	trans	-68.7	-26.6	177.1	-156.1	38	0	0	0	113.3	H281 L314 L350 S351 S352 A356 T395	H281-N354 PolarHBondContact CE1-O 2.83Å; H281-N354 VanDerWaalsContact CE1-O 3.31Å; H281-N354 PolarHBondContact NE2-OD1 3.01Å; H281-N354 VanDerWaalsContact NE2-OD1 3.16Å; L314-N354 HydrophobicContact CD1-CB 4.1Å; L350-N354 PolarHBondContact O-N 3.48Å; S351-N354 WeakPolarHBondContact O-CB 3.24Å; S351-N354 PolarHBondContact O-N 3.31Å; S352-N354 VanDerWaalsContact C-N 3.32Å; S352-N354 PolarHBondContact O-N 3.27Å; N354-A356 PolarHBondContact O-N 2.67Å; N354-T395 HydrophobicContact CB-CG2 3.86Å; N354-T395 VanDerWaalsContact ND2-CG2 3.3Å; N354-T395 WeakPolarHBondContact ND2-CG2 3.4Å
355	M	93.8	Very high	94.3	Very high	45 Å²	45	32.8 Å²	32.8	22%	0.222	19%	0.185	C	C	.	.	T	Hydrogen-bonded Turn	trans	-77.9	0.4	169.3	-66.9	177.6	-152.8	0	0	113.7	S351 S352 A353 A357 T395 L396	S351-M355 WeakPolarHBondContact O-CG 3.48Å; S351-M355 PolarHBondContact O-N 2.91Å; S352-M355 PolarHBondContact O-N 3.09Å; A353-M355 VanDerWaalsContact C-N 3.3Å; A353-M355 PolarHBondContact O-N 3.32Å; M355-A357 PolarHBondContact O-N 3Å; M355-T395 VanDerWaalsContact CE-CB 3.42Å; M355-T395 WeakPolarHBondContact CE-OG1 3.5Å; M355-T395 HydrophobicContact CG-CG2 4.11Å; M355-T395 WeakPolarHBondContact CG-OG1 3.47Å; M355-L396 HydrophobicContact CE-CB 4.22Å; M355-L396 HydrophobicContact CE-CD2 3.51Å; M355-L396 HydrophobicContact CE-CG 3.48Å; M355-L396 VanDerWaalsContact CE-CG 3.48Å; M355-L396 HydrophobicContact SD-CD2 4.17Å; M355-L396 HydrophobicContact SD-CG 4.06Å
356	A	93.9	Very high	94.4	Very high	10 Å²	10	29.2 Å²	29.2	8%	0.083	17%	0.165	C	C	.	.	T	Hydrogen-bonded Turn	trans	55.6	47.6	-172.2	0	0	0	0	0	113	S352 A353 N354 N362 L363 E366	S352-A356 PolarHBondContact O-N 2.96Å; A353-A356 WeakPolarHBondContact O-CA 3.21Å; A353-A356 PolarHBondContact O-N 3.15Å; N354-A356 PolarHBondContact O-N 2.67Å; A356-N362 HydrophobicContact CB-CB 4.14Å; A356-L363 HydrophobicContact CB-CB 4.18Å; A356-L363 WeakPolarHBondContact O-CB 3.35Å; A356-L363 WeakPolarHBondContact O-CD1 3.46Å; A356-E366 HydrophobicContact CB-CG 4.37Å; A356-E366 WeakPolarHBondContact CB-OE2 3.2Å
357	A	93	Very high	94.4	Very high	29 Å²	29	31.2 Å²	31.2	24%	0.24	18%	0.178	C	C	.	.			trans	-71.3	149	173	0	0	0	0	0	112	S352 M355 T360	S352-A357 WeakPolarHBondContact O-CB 3.28Å; S352-A357 PolarHBondContact O-N 2.98Å; M355-A357 PolarHBondContact O-N 3Å; A357-T360 VanDerWaalsContact O-CB 3.27Å; A357-T360 WeakPolarHBondContact O-CB 3.26Å; A357-T360 WeakPolarHBondContact O-CG2 3.47Å; A357-T360 PolarHBondContact O-N 2.93Å; A357-T360 VanDerWaalsContact O-N 3.16Å; A357-T360 PolarHBondContact O-OG1 3Å
358	P	89.2	Confident	94.4	Very high	103 Å²	103	33.7 Å²	33.7	67%	0.669	19%	0.188	S	C	*	.	T	Hydrogen-bonded Turn	trans	-70.4	144.3	171	29.1	-33.5	0	0	0	110.7	L363	P358-L363 HydrophobicContact CB-CD1 4.16Å
359	P	86.7	Confident	94.4	Very high	100 Å²	100	28.7 Å²	28.7	65%	0.649	17%	0.166	S	C	*	.	T	Hydrogen-bonded Turn	cis	-98.5	87.3	-5.6	35.8	-27.3	0	0	0	110.6	I436	P359-I436 WeakPolarHBondContact O-CD1 2.92Å
360	T	93.4	Very high	94.4	Very high	10 Å²	10	29.7 Å²	29.7	6%	0.061	17%	0.171	C	C	.	.			trans	-116.2	150.2	179.1	63.8	0	0	0	0	112.3	A353 A357 N362 L363 L432	A353-T360 HydrophobicContact CB-CG2 4.04Å; A357-T360 VanDerWaalsContact O-CB 3.27Å; A357-T360 WeakPolarHBondContact O-CB 3.26Å; A357-T360 WeakPolarHBondContact O-CG2 3.47Å; A357-T360 PolarHBondContact O-N 2.93Å; A357-T360 VanDerWaalsContact O-N 3.16Å; A357-T360 PolarHBondContact O-OG1 3Å; T360-N362 PolarHBondContact O-N 2.6Å; T360-L363 PolarHBondContact O-N 3.18Å; T360-L432 HydrophobicContact CG2-CD2 3.81Å
361	L	94.2	Very high	94.4	Very high	1 Å²	1	34 Å²	34	1%	0.005	19%	0.194	C	C	.	.	H	α-helix	trans	-63.6	-27.6	177.2	-163.6	84.6	0	0	0	111.4	I305 A306 L364 G365 L435 I436 F442	I305-L361 HydrophobicContact CB-CD2 4.32Å; I305-L361 HydrophobicContact CG2-CD2 4.11Å; A306-L361 HydrophobicContact CB-CB 3.7Å; A306-L361 HydrophobicContact CB-CD2 3.6Å; A306-L361 HydrophobicContact CB-CG 3.88Å; L361-L364 PolarHBondContact O-N 3.42Å; L361-G365 PolarHBondContact O-N 3.14Å; L361-L435 HydrophobicContact CD1-CB 4.22Å; L361-I436 HydrophobicContact CB-CG1 4Å; L361-I436 HydrophobicContact CD1-CG1 3.99Å; L361-F442 HydrophobicContact CD1-CD2 4.36Å
362	N	95.4	Very high	94.4	Very high	1 Å²	1	33.9 Å²	33.9	1%	0.005	19%	0.193	C	C	.	.	H	α-helix	trans	-59.7	-47.3	174.9	-79	-24.1	0	0	0	111	A306 H307 A353 A356 T360 L364 G365 E366	A306-N362 HydrophobicContact CB-CB 4.38Å; A306-N362 WeakPolarHBondContact CB-OD1 2.88Å; H307-N362 PolarHBondContact N-OD1 3.37Å; A353-N362 PolarHBondContact O-ND2 2.81Å; A356-N362 HydrophobicContact CB-CB 4.14Å; T360-N362 PolarHBondContact O-N 2.6Å; N362-L364 VanDerWaalsContact C-N 3.29Å; N362-L364 PolarHBondContact O-N 3.5Å; N362-G365 PolarHBondContact O-N 2.74Å; N362-E366 WeakPolarHBondContact O-CG 3.03Å; N362-E366 PolarHBondContact O-N 3.38Å
363	L	94.8	Very high	94.5	Very high	53 Å²	53	32.7 Å²	32.7	28%	0.277	19%	0.185	S	C	.	.	H	α-helix	trans	-58.6	-42.5	177.3	178.2	141.1	0	0	0	112	A356 P358 T360 E366 I367	A356-L363 HydrophobicContact CB-CB 4.18Å; A356-L363 WeakPolarHBondContact O-CB 3.35Å; A356-L363 WeakPolarHBondContact O-CD1 3.46Å; P358-L363 HydrophobicContact CB-CD1 4.16Å; T360-L363 PolarHBondContact O-N 3.18Å; L363-E366 PolarHBondContact O-N 3.49Å; L363-I367 HydrophobicContact CD2-CD1 3.42Å; L363-I367 VanDerWaalsContact CD2-CD1 3.42Å; L363-I367 HydrophobicContact CD2-CG1 4.45Å; L363-I367 HydrophobicContact CG-CD1 3.84Å; L363-I367 HydrophobicContact CG-CG1 4.44Å; L363-I367 VanDerWaalsContact O-CG1 3.28Å; L363-I367 WeakPolarHBondContact O-CG1 3.14Å; L363-I367 PolarHBondContact O-N 2.85Å
364	L	94.7	Very high	94.5	Very high	30 Å²	30	33.9 Å²	33.9	16%	0.157	19%	0.192	C	C	.	.	H	α-helix	trans	-60	-50.7	177.3	-166.3	154.6	0	0	0	110.2	T302 L361 N362 E366 I367 Y368 M443	T302-L364 HydrophobicContact CG2-CD2 4.22Å; L361-L364 PolarHBondContact O-N 3.42Å; N362-L364 VanDerWaalsContact C-N 3.29Å; N362-L364 PolarHBondContact O-N 3.5Å; L364-E366 PolarHBondContact O-N 3.2Å; L364-I367 PolarHBondContact O-N 3.43Å; L364-Y368 HydrophobicContact CD2-CD2 3.98Å; L364-Y368 HydrophobicContact CD2-CE2 3.83Å; L364-Y368 HydrophobicContact CG-CE2 4.22Å; L364-Y368 WeakPolarHBondContact O-CD2 3.22Å; L364-Y368 PolarHBondContact O-N 2.68Å; L364-M443 HydrophobicContact CD2-CE 4.28Å; L364-M443 HydrophobicContact CD2-CG 4.24Å; L364-M443 HydrophobicContact CD2-SD 3.24Å; L364-M443 WeakPolarHBondContact CD2-SD 3.39Å
365	G	95.1	Very high	94.5	Very high	0 Å²	0	37.6 Å²	37.6	0%	0	22%	0.219	C	C	.	.	H	α-helix	trans	-60.9	-43.6	178.1	0	0	0	0	0	113.5	T302 L361 N362 I367 Y368 L369	T302-G365 WeakPolarHBondContact OG1-CA 3.4Å; L361-G365 PolarHBondContact O-N 3.14Å; N362-G365 PolarHBondContact O-N 2.74Å; G365-I367 PolarHBondContact O-N 3.27Å; G365-Y368 PolarHBondContact O-N 2.83Å; G365-L369 VanDerWaalsContact O-CG 3.28Å; G365-L369 WeakPolarHBondContact O-CG 3.23Å; G365-L369 PolarHBondContact O-N 2.66Å
366	E	95.5	Very high	94.5	Very high	22 Å²	22	40.1 Å²	40.1	10%	0.103	23%	0.226	C	C	.	.	H	α-helix	trans	-64.7	-40.2	-179.7	-70	-170.4	177.7	0	0	112.5	H281 L303 A356 N362 L363 L364 Y368 L369 L370	H281-E366 IonicContact CE1-OE1 2.79Å; H281-E366 PolarHBondContact CE1-OE1 3.01Å; H281-E366 IonicContact ND1-OE1 2.66Å; H281-E366 PolarHBondContact ND1-OE1 2.94Å; L303-E366 HydrophobicContact CD1-CB 4.4Å; L303-E366 HydrophobicContact CD1-CG 3.36Å; A356-E366 HydrophobicContact CB-CG 4.37Å; A356-E366 WeakPolarHBondContact CB-OE2 3.2Å; N362-E366 WeakPolarHBondContact O-CG 3.03Å; N362-E366 PolarHBondContact O-N 3.38Å; L363-E366 PolarHBondContact O-N 3.49Å; L364-E366 PolarHBondContact O-N 3.2Å; E366-Y368 VanDerWaalsContact C-N 3.33Å; E366-Y368 PolarHBondContact O-N 3.24Å; E366-L369 PolarHBondContact O-N 3.5Å; E366-L370 WeakPolarHBondContact O-CB 3.26Å; E366-L370 VanDerWaalsContact O-CG 3.23Å; E366-L370 WeakPolarHBondContact O-CG 3.32Å; E366-L370 PolarHBondContact O-N 2.57Å
367	I	95.4	Very high	94.5	Very high	77 Å²	77	41.1 Å²	41.1	40%	0.395	23%	0.232	S	C	.	.	H	α-helix	trans	-61.1	-43	176.9	-69.9	169.6	0	0	0	111.1	L363 L364 G365 L370 N371	L363-I367 HydrophobicContact CD2-CD1 3.42Å; L363-I367 VanDerWaalsContact CD2-CD1 3.42Å; L363-I367 HydrophobicContact CD2-CG1 4.45Å; L363-I367 HydrophobicContact CG-CD1 3.84Å; L363-I367 HydrophobicContact CG-CG1 4.44Å; L363-I367 VanDerWaalsContact O-CG1 3.28Å; L363-I367 WeakPolarHBondContact O-CG1 3.14Å; L363-I367 PolarHBondContact O-N 2.85Å; L364-I367 PolarHBondContact O-N 3.43Å; G365-I367 PolarHBondContact O-N 3.27Å; I367-L370 PolarHBondContact O-N 2.99Å; I367-N371 VanDerWaalsContact O-CG 3.3Å; I367-N371 PolarHBondContact O-N 3.05Å; I367-N371 VanDerWaalsContact O-N 3.08Å; I367-N371 PolarHBondContact O-ND2 2.82Å
368	Y	95.4	Very high	94.5	Very high	53 Å²	53	49.8 Å²	49.8	21%	0.208	26%	0.259	C	S	.	.	H	α-helix	trans	-65.1	-41.6	178.2	-83.7	-107.8	0	0	0	112	W295 L364 G365 E366 N371 S372 M443	W295-Y368 HydrophobicContact CB-CD1 4.31Å; W295-Y368 HydrophobicContact CD2-CD1 4.08Å; W295-Y368 HydrophobicContact CD2-CE1 4.05Å; W295-Y368 AromaticContact CE3-CD1 3.15Å; W295-Y368 HydrophobicContact CE3-CD1 3.15Å; W295-Y368 AromaticContact CE3-CE1 2.98Å; W295-Y368 HydrophobicContact CE3-CE1 2.98Å; W295-Y368 HydrophobicContact CE3-CG 4.04Å; W295-Y368 AromaticContact CE3-CZ 3.83Å; W295-Y368 HydrophobicContact CH2-CE1 4.12Å; W295-Y368 AromaticContact CZ3-CD1 3.72Å; W295-Y368 HydrophobicContact CZ3-CD1 3.72Å; W295-Y368 AromaticContact CZ3-CE1 3.02Å; W295-Y368 HydrophobicContact CZ3-CE1 3.02Å; W295-Y368 HydrophobicContact CZ3-CE2 4.33Å; W295-Y368 AromaticContact CZ3-CZ 3.43Å; W295-Y368 VanDerWaalsContact CZ3-CZ 3.43Å; L364-Y368 HydrophobicContact CD2-CD2 3.98Å; L364-Y368 HydrophobicContact CD2-CE2 3.83Å; L364-Y368 HydrophobicContact CG-CE2 4.22Å; L364-Y368 WeakPolarHBondContact O-CD2 3.22Å; L364-Y368 PolarHBondContact O-N 2.68Å; G365-Y368 PolarHBondContact O-N 2.83Å; E366-Y368 VanDerWaalsContact C-N 3.33Å; E366-Y368 PolarHBondContact O-N 3.24Å; Y368-N371 PolarHBondContact O-N 3.43Å; Y368-S372 PolarHBondContact O-N 3.31Å; Y368-S372 PolarHBondContact O-OG 2.92Å; Y368-M443 HydrophobicContact CD1-CE 3.32Å; Y368-M443 HydrophobicContact CD2-CE 4.09Å; Y368-M443 HydrophobicContact CE1-CE 2.91Å; Y368-M443 HydrophobicContact CE1-SD 4.42Å; Y368-M443 HydrophobicContact CE2-CE 3.73Å; Y368-M443 HydrophobicContact CE2-SD 4.37Å; Y368-M443 HydrophobicContact CG-CE 3.91Å
369	L	96.8	Very high	94.8	Very high	0 Å²	0	51.4 Å²	51.4	0%	0	26%	0.261	C	S	.	.	H	α-helix	trans	-68	-39.8	177.5	-68.6	170.8	0	0	0	112.3	I284 V285 L303 G365 E366 S372 I373	I284-L369 HydrophobicContact CG2-CB 3.99Å; I284-L369 HydrophobicContact CG2-CD1 3.96Å; V285-L369 HydrophobicContact CG2-CD1 4.36Å; L303-L369 HydrophobicContact CB-CD1 3.99Å; L303-L369 HydrophobicContact CD1-CD1 4.32Å; L303-L369 HydrophobicContact CD2-CD1 4.06Å; L303-L369 HydrophobicContact CG-CD1 4.34Å; G365-L369 VanDerWaalsContact O-CG 3.28Å; G365-L369 WeakPolarHBondContact O-CG 3.23Å; G365-L369 PolarHBondContact O-N 2.66Å; E366-L369 PolarHBondContact O-N 3.5Å; L369-S372 PolarHBondContact O-N 2.7Å; L369-S372 PolarHBondContact O-OG 3.17Å; L369-I373 WeakPolarHBondContact O-CB 3.27Å; L369-I373 VanDerWaalsContact O-CD1 3.32Å; L369-I373 WeakPolarHBondContact O-CD1 3.31Å; L369-I373 WeakPolarHBondContact O-CG1 3.47Å; L369-I373 PolarHBondContact O-N 3.44Å
370	L	96.6	Very high	95.1	Very high	58 Å²	58	46.9 Å²	46.9	30%	0.304	23%	0.231	S	C	.	.	H	α-helix	trans	-61.2	-47.4	175.3	-72.7	171.7	0	0	0	110.5	E366 I367 S372 I373 V374 L384	E366-L370 WeakPolarHBondContact O-CB 3.26Å; E366-L370 VanDerWaalsContact O-CG 3.23Å; E366-L370 WeakPolarHBondContact O-CG 3.32Å; E366-L370 PolarHBondContact O-N 2.57Å; I367-L370 PolarHBondContact O-N 2.99Å; L370-S372 PolarHBondContact O-N 2.99Å; L370-I373 PolarHBondContact O-N 2.63Å; L370-V374 WeakPolarHBondContact O-CB 3.28Å; L370-V374 WeakPolarHBondContact O-CG2 3.39Å; L370-V374 PolarHBondContact O-N 3.08Å; L370-L384 HydrophobicContact CD2-CB 3.79Å; L370-L384 HydrophobicContact CD2-CD1 3.91Å; L370-L384 HydrophobicContact CD2-CD2 3.92Å; L370-L384 HydrophobicContact CD2-CG 4.08Å
371	N	96.1	Very high	95.2	Very high	90 Å²	90	50.6 Å²	50.6	48%	0.481	25%	0.249	S	C	.	.	H	α-helix	trans	-62.7	-41.7	179.1	-71.4	-18	0	0	0	112.3	I367 Y368 S375	I367-N371 VanDerWaalsContact O-CG 3.3Å; I367-N371 PolarHBondContact O-N 3.05Å; I367-N371 VanDerWaalsContact O-N 3.08Å; I367-N371 PolarHBondContact O-ND2 2.82Å; Y368-N371 PolarHBondContact O-N 3.43Å; N371-S375 WeakPolarHBondContact O-CB 3.38Å; N371-S375 PolarHBondContact O-N 2.96Å
372	S	96.4	Very high	95.3	Very high	1 Å²	1	55.6 Å²	55.6	1%	0.007	27%	0.274	C	S	.	.	H	α-helix	trans	-65.1	-46.2	179.2	66.1	0	0	0	0	112.5	T293 G296 Y368 L369 L370 S375 W376	T293-S372 WeakPolarHBondContact OG1-CB 3.4Å; G296-S372 VanDerWaalsContact CA-CB 3.45Å; G296-S372 WeakPolarHBondContact CA-OG 3.4Å; Y368-S372 PolarHBondContact O-N 3.31Å; Y368-S372 PolarHBondContact O-OG 2.92Å; L369-S372 PolarHBondContact O-N 2.7Å; L369-S372 PolarHBondContact O-OG 3.17Å; L370-S372 PolarHBondContact O-N 2.99Å; S372-S375 PolarHBondContact O-N 3.22Å; S372-S375 PolarHBondContact O-OG 3.22Å; S372-W376 PolarHBondContact O-N 2.77Å; S372-W376 VanDerWaalsContact O-N 3.16Å
373	I	96.6	Very high	95.4	Very high	0 Å²	0	57.8 Å²	57.8	0%	0	29%	0.286	C	S	.	.	H	α-helix	trans	-70	-39.4	-176.3	-62	162.8	0	0	0	110.5	L254 I284 S287 T291 L369 L370 S375 W376 S377 S380 L384	L254-I373 HydrophobicContact CD1-CG2 3.99Å; L254-I373 HydrophobicContact CD2-CD1 4.48Å; L254-I373 HydrophobicContact CD2-CG2 4.45Å; I284-I373 HydrophobicContact CG2-CD1 4.24Å; S287-I373 VanDerWaalsContact OG-CD1 3.26Å; S287-I373 WeakPolarHBondContact OG-CD1 3.39Å; T291-I373 HydrophobicContact CG2-CG1 4.31Å; L369-I373 WeakPolarHBondContact O-CB 3.27Å; L369-I373 VanDerWaalsContact O-CD1 3.32Å; L369-I373 WeakPolarHBondContact O-CD1 3.31Å; L369-I373 WeakPolarHBondContact O-CG1 3.47Å; L369-I373 PolarHBondContact O-N 3.44Å; L370-I373 PolarHBondContact O-N 2.63Å; I373-S375 VanDerWaalsContact C-N 3.32Å; I373-S375 PolarHBondContact O-N 3.19Å; I373-W376 WeakPolarHBondContact O-CB 3.27Å; I373-W376 PolarHBondContact O-N 3.1Å; I373-W376 VanDerWaalsContact O-N 3.15Å; I373-S377 PolarHBondContact O-N 3.02Å; I373-S380 PolarHBondContact O-OG 2.8Å; I373-S380 VanDerWaalsContact O-OG 3.14Å; I373-L384 HydrophobicContact CB-CD1 3.92Å; I373-L384 HydrophobicContact CD1-CD2 3.95Å; I373-L384 HydrophobicContact CG2-CD1 3.77Å; I373-L384 HydrophobicContact CG2-CD2 4.26Å; I373-L384 HydrophobicContact CG2-CG 4.27Å
374	V	96.5	Very high	95.4	Very high	24 Å²	24	55.5 Å²	55.5	15%	0.145	27%	0.274	C	S	.	.	H	α-helix	trans	-62.5	-40.2	173.5	171.4	0	0	0	0	111.1	L370 W376 S377 W378 M381 L384	L370-V374 WeakPolarHBondContact O-CB 3.28Å; L370-V374 WeakPolarHBondContact O-CG2 3.39Å; L370-V374 PolarHBondContact O-N 3.08Å; V374-W376 PolarHBondContact O-N 2.88Å; V374-S377 CarbonylContact O-C 3.57Å; V374-S377 PolarHBondContact O-N 3.45Å; V374-W378 HydrophobicContact CG1-CE3 4.29Å; V374-W378 HydrophobicContact CG1-CZ3 4.27Å; V374-M381 HydrophobicContact CB-CE 4.19Å; V374-M381 HydrophobicContact CG1-CE 3.54Å; V374-M381 HydrophobicContact CG2-CE 3.48Å; V374-M381 VanDerWaalsContact CG2-CE 3.48Å; V374-M381 HydrophobicContact CG2-SD 3.74Å; V374-L384 HydrophobicContact CG2-CD1 3.79Å
375	S	94.9	Very high	95.5	Very high	83 Å²	83	56.9 Å²	56.9	58%	0.58	29%	0.286	S	S	*	.	H	α-helix	trans	-64.5	-27.2	176.4	77.9	0	0	0	0	113.4	N371 S372 I373	N371-S375 WeakPolarHBondContact O-CB 3.38Å; N371-S375 PolarHBondContact O-N 2.96Å; S372-S375 PolarHBondContact O-N 3.22Å; S372-S375 PolarHBondContact O-OG 3.22Å; I373-S375 VanDerWaalsContact C-N 3.32Å; I373-S375 PolarHBondContact O-N 3.19Å
376	W	93.8	Very high	95.6	Very high	97 Å²	97	61.5 Å²	61.5	37%	0.367	31%	0.307	S	S	.	.	H	α-helix	trans	-74	-45.1	177	178	79.1	0	0	0	112.2	F247 I250 T291 S372 I373 V374	F247-W376 HydrophobicContact CB-CH2 4.07Å; F247-W376 HydrophobicContact CB-CZ2 3.75Å; I250-W376 HydrophobicContact CB-CZ3 4.48Å; I250-W376 HydrophobicContact CD1-CD2 3.98Å; I250-W376 HydrophobicContact CD1-CE3 4.32Å; I250-W376 HydrophobicContact CD1-CG 4.43Å; I250-W376 HydrophobicContact CD1-CH2 4.47Å; I250-W376 HydrophobicContact CD1-CZ2 4.11Å; I250-W376 HydrophobicContact CG2-CE3 4.06Å; I250-W376 HydrophobicContact CG2-CH2 4.32Å; I250-W376 HydrophobicContact CG2-CZ3 3.82Å; T291-W376 HydrophobicContact CG2-CB 3.88Å; T291-W376 HydrophobicContact CG2-CG 4.2Å; S372-W376 PolarHBondContact O-N 2.77Å; S372-W376 VanDerWaalsContact O-N 3.16Å; I373-W376 WeakPolarHBondContact O-CB 3.27Å; I373-W376 PolarHBondContact O-N 3.1Å; I373-W376 VanDerWaalsContact O-N 3.15Å; V374-W376 PolarHBondContact O-N 2.88Å
377	S	93.6	Very high	95.6	Very high	32 Å²	32	60.8 Å²	60.8	22%	0.224	30%	0.304	C	S	.	.			trans	-156.1	137.5	169.6	66.8	0	0	0	0	112.6	I373 V374 I379 S380	I373-S377 PolarHBondContact O-N 3.02Å; V374-S377 CarbonylContact O-C 3.57Å; V374-S377 PolarHBondContact O-N 3.45Å; S377-I379 PolarHBondContact O-N 3.32Å; S377-S380 WeakPolarHBondContact O-CB 3.43Å; S377-S380 PolarHBondContact O-N 3.16Å; S377-S380 PolarHBondContact O-OG 3.31Å
378	W	93.8	Very high	95.5	Very high	210 Å²	210	59.7 Å²	59.7	80%	0.795	30%	0.302	S	S	*	.	T	Hydrogen-bonded Turn	trans	-61.7	-30.4	177.3	-67.7	99.6	0	0	0	113.7	V374 S380 M381	V374-W378 HydrophobicContact CG1-CE3 4.29Å; V374-W378 HydrophobicContact CG1-CZ3 4.27Å; W378-S380 PolarHBondContact O-N 3.38Å; W378-M381 WeakPolarHBondContact O-CB 3.31Å; W378-M381 PolarHBondContact O-N 3.09Å
379	I	94.8	Very high	95.6	Very high	138 Å²	138	63.6 Å²	63.6	71%	0.708	32%	0.321	S	S	*	.	T	Hydrogen-bonded Turn	trans	-63.2	-31.6	-179.7	-60.8	168.8	0	0	0	111.2	S377 M381 I382	S377-I379 PolarHBondContact O-N 3.32Å; I379-M381 PolarHBondContact O-N 3.47Å; I379-M381 VanDerWaalsContact O-N 3.14Å; I379-I382 PolarHBondContact O-N 3.18Å
380	S	94.6	Very high	95.6	Very high	4 Å²	4	65.2 Å²	65.2	3%	0.028	33%	0.328	C	S	.	.	H	α-helix	trans	-61	-22.4	179.1	71.5	0	0	0	0	113.6	I373 S377 W378 I382 L383 L384	I373-S380 PolarHBondContact O-OG 2.8Å; I373-S380 VanDerWaalsContact O-OG 3.14Å; S377-S380 WeakPolarHBondContact O-CB 3.43Å; S377-S380 PolarHBondContact O-N 3.16Å; S377-S380 PolarHBondContact O-OG 3.31Å; W378-S380 PolarHBondContact O-N 3.38Å; S380-I382 PolarHBondContact O-N 3.15Å; S380-L383 PolarHBondContact O-N 3.11Å; S380-L383 VanDerWaalsContact O-N 3.12Å; S380-L384 WeakPolarHBondContact O-CG 3.46Å; S380-L384 PolarHBondContact O-N 3.13Å
381	M	95.3	Very high	95.5	Very high	89 Å²	89	62.9 Å²	62.9	44%	0.438	32%	0.316	S	S	.	.	H	α-helix	trans	-54.5	-39.7	179.4	-172.9	68.7	82.3	0	0	112.3	V374 W378 I379 L384 S385	V374-M381 HydrophobicContact CB-CE 4.19Å; V374-M381 HydrophobicContact CG1-CE 3.54Å; V374-M381 HydrophobicContact CG2-CE 3.48Å; V374-M381 VanDerWaalsContact CG2-CE 3.48Å; V374-M381 HydrophobicContact CG2-SD 3.74Å; W378-M381 WeakPolarHBondContact O-CB 3.31Å; W378-M381 PolarHBondContact O-N 3.09Å; I379-M381 PolarHBondContact O-N 3.47Å; I379-M381 VanDerWaalsContact O-N 3.14Å; M381-L384 PolarHBondContact O-N 3.31Å; M381-S385 WeakPolarHBondContact O-CB 2.93Å; M381-S385 PolarHBondContact O-N 3.17Å
382	I	96.1	Very high	95.5	Very high	105 Å²	105	60.1 Å²	60.1	54%	0.538	31%	0.306	S	S	.	.	H	α-helix	trans	-63.3	-48.3	-179.7	-61.6	171.7	0	0	0	109.9	I379 S380 L384 S385 F386	I379-I382 PolarHBondContact O-N 3.18Å; S380-I382 PolarHBondContact O-N 3.15Å; I382-L384 PolarHBondContact O-N 3.33Å; I382-S385 PolarHBondContact O-N 2.92Å; I382-S385 PolarHBondContact O-OG 3.09Å; I382-F386 HydrophobicContact CG2-CD2 4.06Å; I382-F386 HydrophobicContact CG2-CE2 3.68Å; I382-F386 VanDerWaalsContact O-CD2 3.23Å; I382-F386 WeakPolarHBondContact O-CD2 3.37Å; I382-F386 PolarHBondContact O-N 2.91Å
383	L	96.1	Very high	95.5	Very high	48 Å²	48	61.4 Å²	61.4	25%	0.251	32%	0.317	S	S	.	.	H	α-helix	trans	-65.6	-40.6	-179.9	-65.4	174	0	0	0	111.7	L254 V255 V258 S380 S385 F386 L387	L254-L383 HydrophobicContact CB-CB 4.21Å; L254-L383 HydrophobicContact CB-CD1 3.77Å; L254-L383 HydrophobicContact CD1-CD1 4.39Å; V255-L383 HydrophobicContact CG2-CD1 3.95Å; V255-L383 HydrophobicContact CG2-CD2 4.38Å; V258-L383 HydrophobicContact CG2-CD2 4.32Å; S380-L383 PolarHBondContact O-N 3.11Å; S380-L383 VanDerWaalsContact O-N 3.12Å; L383-S385 VanDerWaalsContact C-N 3.34Å; L383-S385 PolarHBondContact O-N 3.39Å; L383-F386 PolarHBondContact O-N 3.49Å; L383-L387 WeakPolarHBondContact O-CG 3.35Å; L383-L387 PolarHBondContact O-N 3.13Å
384	L	95.8	Very high	95.5	Very high	4 Å²	4	61.5 Å²	61.5	2%	0.021	32%	0.317	C	S	.	.	H	α-helix	trans	-62.8	-39.7	176.5	-68.6	173.2	0	0	0	112.3	L254 L370 I373 V374 S380 M381 I382 F386 L387 S388	L254-L384 HydrophobicContact CD2-CD2 3.72Å; L254-L384 HydrophobicContact CD2-CG 4.47Å; L370-L384 HydrophobicContact CD2-CB 3.79Å; L370-L384 HydrophobicContact CD2-CD1 3.91Å; L370-L384 HydrophobicContact CD2-CD2 3.92Å; L370-L384 HydrophobicContact CD2-CG 4.08Å; I373-L384 HydrophobicContact CB-CD1 3.92Å; I373-L384 HydrophobicContact CD1-CD2 3.95Å; I373-L384 HydrophobicContact CG2-CD1 3.77Å; I373-L384 HydrophobicContact CG2-CD2 4.26Å; I373-L384 HydrophobicContact CG2-CG 4.27Å; V374-L384 HydrophobicContact CG2-CD1 3.79Å; S380-L384 WeakPolarHBondContact O-CG 3.46Å; S380-L384 PolarHBondContact O-N 3.13Å; M381-L384 PolarHBondContact O-N 3.31Å; I382-L384 PolarHBondContact O-N 3.33Å; L384-F386 VanDerWaalsContact C-N 3.32Å; L384-F386 PolarHBondContact O-N 3.47Å; L384-L387 HydrophobicContact CD2-CD1 4.28Å; L384-L387 PolarHBondContact O-N 3Å; L384-S388 PolarHBondContact O-N 2.93Å; L384-S388 PolarHBondContact O-OG 3.27Å
385	S	96.1	Very high	95.5	Very high	60 Å²	60	60.5 Å²	60.5	42%	0.42	31%	0.311	S	S	.	.	H	α-helix	trans	-62.2	-39.6	176.6	75.7	0	0	0	0	112.4	M381 I382 L383 S388 F389	M381-S385 WeakPolarHBondContact O-CB 2.93Å; M381-S385 PolarHBondContact O-N 3.17Å; I382-S385 PolarHBondContact O-N 2.92Å; I382-S385 PolarHBondContact O-OG 3.09Å; L383-S385 VanDerWaalsContact C-N 3.34Å; L383-S385 PolarHBondContact O-N 3.39Å; S385-S388 PolarHBondContact O-OG 3.41Å; S385-F389 VanDerWaalsContact O-CB 3.27Å; S385-F389 WeakPolarHBondContact O-CB 3.29Å; S385-F389 PolarHBondContact O-N 3.25Å; S385-F389 VanDerWaalsContact O-N 3.09Å
386	F	96.7	Very high	95.5	Very high	97 Å²	97	61.2 Å²	61.2	43%	0.425	31%	0.308	S	S	.	.	H	α-helix	trans	-69.6	-41.3	174.6	-73.4	-56.1	0	0	0	111.8	V258 I382 L383 L384 F389 F390	V258-F386 HydrophobicContact CG1-CB 4.25Å; V258-F386 HydrophobicContact CG2-CB 4.11Å; I382-F386 HydrophobicContact CG2-CD2 4.06Å; I382-F386 HydrophobicContact CG2-CE2 3.68Å; I382-F386 VanDerWaalsContact O-CD2 3.23Å; I382-F386 WeakPolarHBondContact O-CD2 3.37Å; I382-F386 PolarHBondContact O-N 2.91Å; L383-F386 PolarHBondContact O-N 3.49Å; L384-F386 VanDerWaalsContact C-N 3.32Å; L384-F386 PolarHBondContact O-N 3.47Å; F386-F389 PolarHBondContact O-N 3.31Å; F386-F390 HydrophobicContact CB-CD2 4.11Å; F386-F390 HydrophobicContact CB-CE2 3.96Å; F386-F390 AromaticContact CD1-CE2 3.97Å; F386-F390 HydrophobicContact CD1-CE2 3.97Å; F386-F390 HydrophobicContact CD1-CZ 4.44Å; F386-F390 HydrophobicContact CG-CE2 4.3Å; F386-F390 WeakPolarHBondContact O-CB 3.31Å; F386-F390 WeakPolarHBondContact O-CD2 3.09Å; F386-F390 WeakPolarHBondContact O-CG 3.38Å; F386-F390 PolarHBondContact O-N 3.1Å
387	L	95.7	Very high	95.6	Very high	7 Å²	7	58.8 Å²	58.8	4%	0.037	30%	0.299	C	S	.	.	H	α-helix	trans	-58.2	-49.2	177.6	-77.9	166.3	0	0	0	112.3	L254 V258 I284 L383 L384 S391	L254-L387 HydrophobicContact CD2-CD1 3.81Å; V258-L387 HydrophobicContact CG2-CD1 4.43Å; V258-L387 HydrophobicContact CG2-CD2 3.9Å; V258-L387 HydrophobicContact CG2-CG 3.66Å; V258-L387 VanDerWaalsContact N-CD2 3.28Å; I284-L387 HydrophobicContact CD1-CB 4.47Å; I284-L387 HydrophobicContact CG1-CD1 4.21Å; L383-L387 WeakPolarHBondContact O-CG 3.35Å; L383-L387 PolarHBondContact O-N 3.13Å; L384-L387 HydrophobicContact CD2-CD1 4.28Å; L384-L387 PolarHBondContact O-N 3Å; L387-S391 WeakPolarHBondContact O-CB 3.41Å; L387-S391 PolarHBondContact O-N 3.27Å
388	S	94.5	Very high	95.7	Very high	53 Å²	53	57.4 Å²	57.4	37%	0.371	29%	0.289	S	S	.	.	H	α-helix	trans	-70.4	-35.6	179.9	61.6	0	0	0	0	112.6	L384 S385 S391 A392	L384-S388 PolarHBondContact O-N 2.93Å; L384-S388 PolarHBondContact O-OG 3.27Å; S385-S388 PolarHBondContact O-OG 3.41Å; S388-S391 PolarHBondContact O-OG 3.38Å; S388-A392 PolarHBondContact O-N 3.05Å
389	F	96.4	Very high	95.8	Very high	136 Å²	136	49 Å²	49	60%	0.596	26%	0.258	S	S	*	.	H	α-helix	trans	-64.7	-48.4	174.3	177.9	-98.5	0	0	0	111.8	S385 F386 S391 A392 A393	S385-F389 VanDerWaalsContact O-CB 3.27Å; S385-F389 WeakPolarHBondContact O-CB 3.29Å; S385-F389 PolarHBondContact O-N 3.25Å; S385-F389 VanDerWaalsContact O-N 3.09Å; F386-F389 PolarHBondContact O-N 3.31Å; F389-S391 VanDerWaalsContact C-N 3.31Å; F389-S391 PolarHBondContact O-N 3.01Å; F389-A392 PolarHBondContact O-N 3.06Å; F389-A393 PolarHBondContact O-N 3.19Å
390	F	96.5	Very high	95.8	Very high	33 Å²	33	44.6 Å²	44.6	15%	0.145	24%	0.239	C	C	.	.	H	α-helix	trans	-70.6	-28.3	-179.9	-68.6	-54.3	0	0	0	112.4	V258 S261 L262 L265 F386 A393 Y394	V258-F390 HydrophobicContact CG1-CD2 4.36Å; V258-F390 HydrophobicContact CG1-CE2 4.24Å; S261-F390 WeakPolarHBondContact OG-CB 3.41Å; S261-F390 WeakPolarHBondContact OG-CD2 3.5Å; L262-F390 HydrophobicContact CD2-CD1 4.18Å; L262-F390 HydrophobicContact CD2-CD2 4.38Å; L262-F390 HydrophobicContact CD2-CE1 3.67Å; L262-F390 HydrophobicContact CD2-CE2 3.91Å; L262-F390 HydrophobicContact CD2-CZ 3.54Å; L262-F390 HydrophobicContact CG-CE2 4.34Å; L262-F390 HydrophobicContact CG-CZ 4.44Å; L265-F390 HydrophobicContact CD1-CD1 4Å; L265-F390 HydrophobicContact CD1-CE1 4.38Å; F386-F390 HydrophobicContact CB-CD2 4.11Å; F386-F390 HydrophobicContact CB-CE2 3.96Å; F386-F390 AromaticContact CD1-CE2 3.97Å; F386-F390 HydrophobicContact CD1-CE2 3.97Å; F386-F390 HydrophobicContact CD1-CZ 4.44Å; F386-F390 HydrophobicContact CG-CE2 4.3Å; F386-F390 WeakPolarHBondContact O-CB 3.31Å; F386-F390 WeakPolarHBondContact O-CD2 3.09Å; F386-F390 WeakPolarHBondContact O-CG 3.38Å; F386-F390 PolarHBondContact O-N 3.1Å; F390-A393 PolarHBondContact O-N 3.29Å; F390-Y394 WeakPolarHBondContact O-CD1 3.32Å; F390-Y394 PolarHBondContact O-N 3.37Å
391	S	94.7	Very high	95.7	Very high	9 Å²	9	48.6 Å²	48.6	6%	0.063	26%	0.256	C	S	.	.	H	α-helix	trans	-60.8	-43.3	172.1	74.7	0	0	0	0	112.5	L387 S388 F389 T395	L387-S391 WeakPolarHBondContact O-CB 3.41Å; L387-S391 PolarHBondContact O-N 3.27Å; S388-S391 PolarHBondContact O-OG 3.38Å; F389-S391 VanDerWaalsContact C-N 3.31Å; F389-S391 PolarHBondContact O-N 3.01Å; S391-T395 WeakPolarHBondContact O-CB 3.43Å; S391-T395 VanDerWaalsContact O-CG2 3.28Å; S391-T395 WeakPolarHBondContact O-CG2 3.24Å; S391-T395 PolarHBondContact O-N 3.33Å; S391-T395 PolarHBondContact O-OG1 3.44Å
392	A	96.2	Very high	95.6	Very high	33 Å²	33	44.3 Å²	44.3	27%	0.273	24%	0.235	S	C	.	.	H	α-helix	trans	-65.4	-40.5	171	0	0	0	0	0	112.5	S388 F389 T395 L396	S388-A392 PolarHBondContact O-N 3.05Å; F389-A392 PolarHBondContact O-N 3.06Å; A392-T395 WeakPolarHBondContact CA-OG1 3.21Å; A392-T395 PolarHBondContact O-OG1 3.27Å; A392-L396 WeakPolarHBondContact O-CB 3.06Å; A392-L396 VanDerWaalsContact O-CG 3.31Å; A392-L396 WeakPolarHBondContact O-CG 3.23Å; A392-L396 PolarHBondContact O-N 3.26Å
393	A	97	Very high	95.5	Very high	28 Å²	28	39.4 Å²	39.4	23%	0.231	21%	0.21	C	C	.	.	H	α-helix	trans	-64.7	-49	-178.2	0	0	0	0	0	113	L265 F389 F390 T395 L396 Y397	L265-A393 HydrophobicContact CD2-CB 4.09Å; F389-A393 PolarHBondContact O-N 3.19Å; F390-A393 PolarHBondContact O-N 3.29Å; A393-T395 VanDerWaalsContact C-N 3.34Å; A393-T395 PolarHBondContact O-N 3.13Å; A393-L396 PolarHBondContact O-N 3.22Å; A393-Y397 VanDerWaalsContact O-CB 3.28Å; A393-Y397 WeakPolarHBondContact O-CB 3.36Å; A393-Y397 PolarHBondContact O-N 3.23Å
394	Y	96.6	Very high	95.3	Very high	2 Å²	2	41.7 Å²	41.7	1%	0.008	22%	0.219	C	C	.	.	H	α-helix	trans	-72.5	-27.9	-177.2	67.5	-117.3	0	0	0	113.1	C264 L273 S277 H281 F390 Y397 L398	C264-Y394 HydrophobicContact CB-CD1 3.92Å; C264-Y394 HydrophobicContact CB-CG 3.88Å; L273-Y394 HydrophobicContact CD2-CD2 4.4Å; S277-Y394 VanDerWaalsContact CB-CE2 3.46Å; H281-Y394 PolarHBondContact NE2-OH 2.98Å; F390-Y394 WeakPolarHBondContact O-CD1 3.32Å; F390-Y394 PolarHBondContact O-N 3.37Å; Y394-Y397 WeakPolarHBondContact O-CB 3.05Å; Y394-L398 WeakPolarHBondContact O-CB 3.3Å; Y394-L398 PolarHBondContact O-N 3.43Å
395	T	95.6	Very high	95.1	Very high	2 Å²	2	44 Å²	44	1%	0.012	24%	0.243	C	C	.	.	H	α-helix	trans	-73.5	-40.3	176.2	44.8	0	0	0	0	111.1	N354 M355 S391 A392 A393 Y397 L398 Y399	N354-T395 HydrophobicContact CB-CG2 3.86Å; N354-T395 VanDerWaalsContact ND2-CG2 3.3Å; N354-T395 WeakPolarHBondContact ND2-CG2 3.4Å; M355-T395 VanDerWaalsContact CE-CB 3.42Å; M355-T395 WeakPolarHBondContact CE-OG1 3.5Å; M355-T395 HydrophobicContact CG-CG2 4.11Å; M355-T395 WeakPolarHBondContact CG-OG1 3.47Å; S391-T395 WeakPolarHBondContact O-CB 3.43Å; S391-T395 VanDerWaalsContact O-CG2 3.28Å; S391-T395 WeakPolarHBondContact O-CG2 3.24Å; S391-T395 PolarHBondContact O-N 3.33Å; S391-T395 PolarHBondContact O-OG1 3.44Å; A392-T395 WeakPolarHBondContact CA-OG1 3.21Å; A392-T395 PolarHBondContact O-OG1 3.27Å; A393-T395 VanDerWaalsContact C-N 3.34Å; A393-T395 PolarHBondContact O-N 3.13Å; T395-Y397 VanDerWaalsContact C-N 3.32Å; T395-L398 PolarHBondContact O-N 3.06Å; T395-Y399 PolarHBondContact O-N 2.81Å
396	L	95.3	Very high	94.7	Very high	98 Å²	98	50.2 Å²	50.2	51%	0.513	26%	0.263	S	S	.	.	H	α-helix	trans	-66.1	-38.2	172	-74.9	172.8	0	0	0	110.6	M355 A392 A393 Y399 S400	M355-L396 HydrophobicContact CE-CB 4.22Å; M355-L396 HydrophobicContact CE-CD2 3.51Å; M355-L396 HydrophobicContact CE-CG 3.48Å; M355-L396 VanDerWaalsContact CE-CG 3.48Å; M355-L396 HydrophobicContact SD-CD2 4.17Å; M355-L396 HydrophobicContact SD-CG 4.06Å; A392-L396 WeakPolarHBondContact O-CB 3.06Å; A392-L396 VanDerWaalsContact O-CG 3.31Å; A392-L396 WeakPolarHBondContact O-CG 3.23Å; A392-L396 PolarHBondContact O-N 3.26Å; A393-L396 PolarHBondContact O-N 3.22Å; L396-Y399 PolarHBondContact O-N 2.96Å; L396-S400 VanDerWaalsContact O-CB 3.22Å; L396-S400 WeakPolarHBondContact O-CB 3.3Å; L396-S400 PolarHBondContact O-N 3.24Å; L396-S400 PolarHBondContact O-OG 2.86Å
397	Y	95.6	Very high	94.1	Very high	46 Å²	46	48.1 Å²	48.1	18%	0.18	26%	0.256	C	S	.	.	H	α-helix	trans	-59.1	-49.3	171.6	173.5	-95.5	0	0	0	111.3	L273 A393 Y394 T395 Y399 S400 F401	L273-Y397 HydrophobicContact CD1-CD1 3.7Å; L273-Y397 HydrophobicContact CD1-CE1 3.73Å; A393-Y397 VanDerWaalsContact O-CB 3.28Å; A393-Y397 WeakPolarHBondContact O-CB 3.36Å; A393-Y397 PolarHBondContact O-N 3.23Å; Y394-Y397 WeakPolarHBondContact O-CB 3.05Å; T395-Y397 VanDerWaalsContact C-N 3.32Å; Y397-Y399 PolarHBondContact O-N 3.27Å; Y397-S400 PolarHBondContact O-N 2.96Å; Y397-S400 PolarHBondContact O-OG 2.94Å; Y397-F401 AromaticContact CD2-CD2 3.27Å; Y397-F401 HydrophobicContact CD2-CD2 3.27Å; Y397-F401 AromaticContact CD2-CE2 3.15Å; Y397-F401 HydrophobicContact CD2-CE2 3.15Å; Y397-F401 HydrophobicContact CD2-CG 4.27Å; Y397-F401 HydrophobicContact CD2-CZ 4.08Å; Y397-F401 HydrophobicContact CE2-CD1 4.39Å; Y397-F401 AromaticContact CE2-CD2 3.33Å; Y397-F401 HydrophobicContact CE2-CD2 3.33Å; Y397-F401 HydrophobicContact CE2-CE1 4.25Å; Y397-F401 AromaticContact CE2-CE2 3.17Å; Y397-F401 HydrophobicContact CE2-CE2 3.17Å; Y397-F401 AromaticContact CE2-CG 3.97Å; Y397-F401 HydrophobicContact CE2-CG 3.97Å; Y397-F401 AromaticContact CE2-CZ 3.65Å; Y397-F401 HydrophobicContact CE2-CZ 3.65Å; Y397-F401 AromaticContact CG-CD2 3.97Å; Y397-F401 HydrophobicContact CG-CD2 3.97Å; Y397-F401 HydrophobicContact CG-CE2 4.24Å; Y397-F401 WeakPolarHBondContact O-CB 3.4Å; Y397-F401 WeakPolarHBondContact O-CD2 3.34Å; Y397-F401 PolarHBondContact O-N 2.63Å
398	L	96	Very high	93.6	Very high	4 Å²	4	52.5 Å²	52.5	2%	0.021	28%	0.275	C	S	.	.	H	α-helix	trans	-57.2	-46.6	176	171.6	162	0	0	0	111.7	L273 I274 W347 Y394 T395 S402	L273-L398 HydrophobicContact CD1-CB 4.43Å; L273-L398 HydrophobicContact CD2-CB 4.2Å; L273-L398 HydrophobicContact CD2-CD1 3.88Å; I274-L398 HydrophobicContact CG1-CD1 3.91Å; W347-L398 HydrophobicContact CE3-CD2 3.68Å; W347-L398 HydrophobicContact CZ3-CD1 4.44Å; W347-L398 HydrophobicContact CZ3-CD2 3.49Å; W347-L398 VanDerWaalsContact CZ3-CD2 3.49Å; W347-L398 HydrophobicContact CZ3-CG 4.27Å; Y394-L398 WeakPolarHBondContact O-CB 3.3Å; Y394-L398 PolarHBondContact O-N 3.43Å; T395-L398 PolarHBondContact O-N 3.06Å; L398-S402 WeakPolarHBondContact O-CB 3.31Å; L398-S402 PolarHBondContact O-N 2.9Å; L398-S402 PolarHBondContact O-OG 3.06Å
399	Y	96	Very high	93	Very high	33 Å²	33	55 Å²	55	13%	0.129	29%	0.292	C	S	.	.	H	α-helix	trans	-68.4	-50	-178.5	-179.3	-100.6	0	0	0	111.7	W347 F348 T395 L396 Y397 S402 Q403 H404	W347-Y399 HydrophobicContact CB-CD2 4.1Å; W347-Y399 HydrophobicContact CB-CE2 4.08Å; F348-Y399 HydrophobicContact CB-CD2 4.46Å; F348-Y399 HydrophobicContact CB-CE2 3.68Å; F348-Y399 HydrophobicContact CD2-CE1 4.41Å; F348-Y399 HydrophobicContact CD2-CE2 4.38Å; T395-Y399 PolarHBondContact O-N 2.81Å; L396-Y399 PolarHBondContact O-N 2.96Å; Y397-Y399 PolarHBondContact O-N 3.27Å; Y399-S402 PolarHBondContact O-N 3.17Å; Y399-S402 PolarHBondContact O-OG 3.48Å; Y399-Q403 HydrophobicContact CD2-CG 3.77Å; Y399-Q403 HydrophobicContact CE2-CB 4.25Å; Y399-Q403 HydrophobicContact CE2-CG 3.63Å; Y399-Q403 HydrophobicContact CG-CG 4.43Å; Y399-Q403 WeakPolarHBondContact O-CB 3.38Å; Y399-Q403 WeakPolarHBondContact O-CG 3.35Å; Y399-Q403 PolarHBondContact O-N 3.5Å; Y399-H404 AromaticContact CE1-NE2 3.66Å
400	S	94.8	Very high	92.3	Very high	45 Å²	45	50.8 Å²	50.8	32%	0.315	29%	0.287	S	S	.	.	H	α-helix	trans	-65.1	-45.6	-174.6	58.2	0	0	0	0	112.9	L396 Y397 S402 H404	L396-S400 VanDerWaalsContact O-CB 3.22Å; L396-S400 WeakPolarHBondContact O-CB 3.3Å; L396-S400 PolarHBondContact O-N 3.24Å; L396-S400 PolarHBondContact O-OG 2.86Å; Y397-S400 PolarHBondContact O-N 2.96Å; Y397-S400 PolarHBondContact O-OG 2.94Å; S400-S402 PolarHBondContact O-N 3.4Å; S400-H404 WeakPolarHBondContact O-CB 3.39Å; S400-H404 PolarHBondContact O-N 3.42Å; S400-H404 VanDerWaalsContact O-N 3.07Å
401	F	93.8	Very high	91.3	Very high	88 Å²	88	50.6 Å²	50.6	39%	0.386	29%	0.289	S	S	.	.	H	α-helix	trans	-71.9	-29.9	-179.2	-81.4	-95	0	0	0	112.7	M330 K334 Y397	M330-F401 HydrophobicContact CE-CB 3.33Å; M330-F401 HydrophobicContact CE-CG 4.47Å; K334-F401 WeakPolarHBondContact CG-O 3.43Å; Y397-F401 AromaticContact CD2-CD2 3.27Å; Y397-F401 HydrophobicContact CD2-CD2 3.27Å; Y397-F401 AromaticContact CD2-CE2 3.15Å; Y397-F401 HydrophobicContact CD2-CE2 3.15Å; Y397-F401 HydrophobicContact CD2-CG 4.27Å; Y397-F401 HydrophobicContact CD2-CZ 4.08Å; Y397-F401 HydrophobicContact CE2-CD1 4.39Å; Y397-F401 AromaticContact CE2-CD2 3.33Å; Y397-F401 HydrophobicContact CE2-CD2 3.33Å; Y397-F401 HydrophobicContact CE2-CE1 4.25Å; Y397-F401 AromaticContact CE2-CE2 3.17Å; Y397-F401 HydrophobicContact CE2-CE2 3.17Å; Y397-F401 AromaticContact CE2-CG 3.97Å; Y397-F401 HydrophobicContact CE2-CG 3.97Å; Y397-F401 AromaticContact CE2-CZ 3.65Å; Y397-F401 HydrophobicContact CE2-CZ 3.65Å; Y397-F401 AromaticContact CG-CD2 3.97Å; Y397-F401 HydrophobicContact CG-CD2 3.97Å; Y397-F401 HydrophobicContact CG-CE2 4.24Å; Y397-F401 WeakPolarHBondContact O-CB 3.4Å; Y397-F401 WeakPolarHBondContact O-CD2 3.34Å; Y397-F401 PolarHBondContact O-N 2.63Å
402	S	93	Very high	90.1	Very high	0 Å²	0	59.6 Å²	59.6	0%	0	32%	0.323	C	S	.	.	H	α-helix	trans	-81.9	-43.4	178.4	61.6	0	0	0	0	113.2	N333 K334 G335 L336 L398 Y399 S400	N333-S402 CarbonylContact O-C 3.55Å; N333-S402 VanDerWaalsContact O-CA 3.26Å; N333-S402 WeakPolarHBondContact O-CA 3.38Å; K334-S402 CarbonylContact C-O 3.45Å; G335-S402 PolarHBondContact N-O 3.28Å; G335-S402 VanDerWaalsContact N-O 3.17Å; L336-S402 PolarHBondContact N-O 3.28Å; L398-S402 WeakPolarHBondContact O-CB 3.31Å; L398-S402 PolarHBondContact O-N 2.9Å; L398-S402 PolarHBondContact O-OG 3.06Å; Y399-S402 PolarHBondContact O-N 3.17Å; Y399-S402 PolarHBondContact O-OG 3.48Å; S400-S402 PolarHBondContact O-N 3.4Å
403	Q	93.7	Very high	88.5	Confident	1 Å²	1	60.6 Å²	60.6	1%	0.005	33%	0.328	C	S	.	.	H	α-helix	trans	-92.4	-38	-170.9	-53	-48	-48.5	0	0	113.2	G335 L336 L337 T344 W347 Y399	G335-Q403 CarbonylContact C-O 3.16Å; G335-Q403 VanDerWaalsContact CA-O 3.27Å; G335-Q403 WeakPolarHBondContact CA-O 3.48Å; L336-Q403 PolarHBondContact N-O 2.93Å; L337-Q403 WeakPolarHBondContact CB-O 3.27Å; L337-Q403 PolarHBondContact N-O 3.02Å; L337-Q403 VanDerWaalsContact N-O 3.07Å; T344-Q403 HydrophobicContact CG2-CG 4.48Å; W347-Q403 HydrophobicContact CB-CG 4.22Å; W347-Q403 VanDerWaalsContact CD1-NE2 3.26Å; W347-Q403 HydrophobicContact CG-CG 4.41Å; W347-Q403 VanDerWaalsContact CG-NE2 3.29Å; Y399-Q403 HydrophobicContact CD2-CG 3.77Å; Y399-Q403 HydrophobicContact CE2-CB 4.25Å; Y399-Q403 HydrophobicContact CE2-CG 3.63Å; Y399-Q403 HydrophobicContact CG-CG 4.43Å; Y399-Q403 WeakPolarHBondContact O-CB 3.38Å; Y399-Q403 WeakPolarHBondContact O-CG 3.35Å; Y399-Q403 PolarHBondContact O-N 3.5Å
404	H	92	Very high	86.9	Confident	97 Å²	97	65.2 Å²	65.2	45%	0.449	34%	0.343	S	S	.	.	S	Bend	trans	-90	164.3	-177.3	-63.3	-60.1	0	0	0	112.8	G335 Y399 S400	G335-H404 WeakPolarHBondContact CA-O 3.47Å; G335-H404 PolarHBondContact N-O 2.86Å; G335-H404 VanDerWaalsContact N-O 3.08Å; Y399-H404 AromaticContact CE1-NE2 3.66Å; S400-H404 WeakPolarHBondContact O-CB 3.39Å; S400-H404 PolarHBondContact O-N 3.42Å; S400-H404 VanDerWaalsContact O-N 3.07Å
405	G	90.5	Very high	86.1	Confident	51 Å²	51	67.8 Å²	67.8	53%	0.526	36%	0.361	S	S	.	.	S	Bend	trans	99.6	-173.8	174.8	0	0	0	0	0	114.4	G335	G335-G405 WeakPolarHBondContact CA-O 2.85Å
406	K	87.5	Confident	85.4	Confident	191 Å²	191	71.4 Å²	71.4	83%	0.83	39%	0.387	S	S	*	.	P	Polyproline II helix	trans	-80	144.6	176.8	-65.5	-178.6	-178.1	179.1	0	109.9
407	L	85.4	Confident	84.9	Confident	53 Å²	53	67.6 Å²	67.6	28%	0.277	37%	0.371	S	S	.	.	P	Polyproline II helix	trans	-68.2	142.4	177.6	-64.3	164.4	0	0	0	110.3	K334 G335 N338 F339 S409	K334-L407 WeakPolarHBondContact O-CD2 3.24Å; G335-L407 WeakPolarHBondContact O-CD2 3.46Å; N338-L407 HydrophobicContact CB-CD1 3.68Å; N338-L407 HydrophobicContact CB-CD2 4.38Å; N338-L407 HydrophobicContact CB-CG 4.21Å; F339-L407 HydrophobicContact CD1-CD1 3.66Å; F339-L407 HydrophobicContact CD1-CD2 4.4Å; F339-L407 HydrophobicContact CD2-CD1 4.01Å; F339-L407 HydrophobicContact CD2-CD2 3.18Å; F339-L407 HydrophobicContact CD2-CG 4.06Å; F339-L407 HydrophobicContact CE1-CD1 3.13Å; F339-L407 HydrophobicContact CE1-CD2 4.25Å; F339-L407 HydrophobicContact CE1-CG 4.09Å; F339-L407 HydrophobicContact CE2-CB 3.78Å; F339-L407 HydrophobicContact CE2-CD1 3.57Å; F339-L407 HydrophobicContact CE2-CD2 3.02Å; F339-L407 HydrophobicContact CE2-CG 3.55Å; F339-L407 HydrophobicContact CG-CD1 4.06Å; F339-L407 HydrophobicContact CG-CD2 3.91Å; F339-L407 HydrophobicContact CZ-CB 3.66Å; F339-L407 HydrophobicContact CZ-CD1 3.06Å; F339-L407 HydrophobicContact CZ-CD2 3.58Å; F339-L407 HydrophobicContact CZ-CG 3.52Å; L407-S409 PolarHBondContact O-N 3.18Å
408	F	84.7	Confident	84.7	Confident	99 Å²	99	69 Å²	69	43%	0.434	38%	0.378	S	S	.	.	P	Polyproline II helix	trans	-69.5	122	174.3	-177.8	-103.8	0	0	0	109.8	I332 G410 V411	I332-F408 HydrophobicContact CG2-CD1 4.24Å; F408-G410 PolarHBondContact O-N 2.87Å; F408-V411 HydrophobicContact CD1-CG2 3.95Å; F408-V411 HydrophobicContact CE1-CG2 4.36Å
409	S	82.8	Confident	84.5	Confident	106 Å²	106	75.9 Å²	75.9	74%	0.741	41%	0.413	S	S	*	.	T	Hydrogen-bonded Turn	trans	-68.7	-16.6	-171.9	55.1	0	0	0	0	114.6	L407 V411	L407-S409 PolarHBondContact O-N 3.18Å; S409-V411 PolarHBondContact O-N 2.94Å
410	G	80.4	Confident	84.4	Confident	48 Å²	48	75.9 Å²	75.9	50%	0.495	41%	0.413	S	S	.	.	T	Hydrogen-bonded Turn	trans	-84	1.5	-174.6	0	0	0	0	0	115.8	F408	F408-G410 PolarHBondContact O-N 2.87Å
411	V	75.3	Confident	84.4	Confident	28 Å²	28	74 Å²	74	17%	0.17	40%	0.399	C	S	.	.			trans	-123.3	130.6	-176.3	-178.1	0	0	0	0	111.3	L325 I332 F408 S409 S413	L325-V411 HydrophobicContact CD2-CB 4.15Å; L325-V411 HydrophobicContact CD2-CG1 3.53Å; L325-V411 HydrophobicContact CD2-CG2 4.46Å; I332-V411 HydrophobicContact CG2-CG2 4.25Å; F408-V411 HydrophobicContact CD1-CG2 3.95Å; F408-V411 HydrophobicContact CE1-CG2 4.36Å; S409-V411 PolarHBondContact O-N 2.94Å; V411-S413 VanDerWaalsContact CG1-OG 3.27Å; V411-S413 WeakPolarHBondContact CG1-OG 3.35Å
412	Y	69.2	Low	84.5	Confident	198 Å²	198	72.3 Å²	72.3	78%	0.776	39%	0.391	S	S	*	.			trans	-113.4	4.7	-174.8	-69.5	-79.1	0	0	0	114.4	F414	Y412-F414 WeakPolarHBondContact O-CD2 3.37Å; Y412-F414 WeakPolarHBondContact O-CE2 3.11Å; Y412-F414 PolarHBondContact O-N 2.91Å
413	S	64	Low	84.7	Confident	54 Å²	54	76.1 Å²	76.1	38%	0.378	41%	0.411	S	S	.	.			trans	-87.7	107.6	-176	44.6	0	0	0	0	111.8	R324 V411	R324-S413 WeakPolarHBondContact O-CB 3.23Å; R324-S413 PolarHBondContact O-OG 3.14Å; V411-S413 VanDerWaalsContact CG1-OG 3.27Å; V411-S413 WeakPolarHBondContact CG1-OG 3.35Å
414	F	63.8	Low	84.8	Confident	125 Å²	125	76.2 Å²	76.2	55%	0.548	41%	0.411	S	S	.	.			trans	-115.1	118.7	-179.2	-53.4	-54.7	0	0	0	112	F339 Y412	F339-F414 AromaticContact CD1-CD1 3.74Å; F339-F414 HydrophobicContact CD1-CD1 3.74Å; F339-F414 AromaticContact CD1-CE1 3.74Å; F339-F414 HydrophobicContact CD1-CE1 3.74Å; F339-F414 HydrophobicContact CD2-CD1 4.46Å; F339-F414 HydrophobicContact CD2-CE1 4.23Å; F339-F414 AromaticContact CE1-CD1 3.65Å; F339-F414 HydrophobicContact CE1-CD1 3.65Å; F339-F414 AromaticContact CE1-CE1 3.14Å; F339-F414 HydrophobicContact CE1-CE1 3.14Å; F339-F414 AromaticContact CE1-CZ 3.78Å; F339-F414 HydrophobicContact CE1-CZ 3.78Å; F339-F414 HydrophobicContact CE2-CD1 4.34Å; F339-F414 AromaticContact CE2-CE1 3.68Å; F339-F414 HydrophobicContact CE2-CE1 3.68Å; F339-F414 HydrophobicContact CG-CD1 4.18Å; F339-F414 HydrophobicContact CG-CE1 4.26Å; F339-F414 AromaticContact CZ-CD1 3.99Å; F339-F414 HydrophobicContact CZ-CD1 3.99Å; F339-F414 AromaticContact CZ-CE1 3.13Å; F339-F414 HydrophobicContact CZ-CE1 3.13Å; F339-F414 AromaticContact CZ-CZ 3.79Å; F339-F414 HydrophobicContact CZ-CZ 3.79Å; Y412-F414 WeakPolarHBondContact O-CD2 3.37Å; Y412-F414 WeakPolarHBondContact O-CE2 3.11Å; Y412-F414 PolarHBondContact O-N 2.91Å
415	S	79.5	Confident	85	Confident	57 Å²	57	71.6 Å²	71.6	40%	0.399	39%	0.39	S	S	.	.			trans	-140.7	131.4	160.1	60.8	0	0	0	0	108.5	R324 G417	R324-S415 WeakPolarHBondContact CD-O 3.34Å; R324-S415 WeakPolarHBondContact CD-OG 3.28Å; R324-S415 PolarHBondContact NE-O 3.16Å; R324-S415 PolarHBondContact NE-OG 3.17Å; R324-S415 VanDerWaalsContact NE-OG 3.07Å; S415-G417 PolarHBondContact O-N 2.62Å
416	S	79.9	Confident	85.3	Confident	78 Å²	78	72.6 Å²	72.6	55%	0.545	38%	0.383	S	S	.	.			trans	-68.5	-22.7	-177.4	53	0	0	0	0	113.2	Y422	S416-Y422 PolarHBondContact O-OH 3.32Å
417	G	85.4	Confident	85.7	Confident	18 Å²	18	65.1 Å²	65.1	19%	0.186	35%	0.351	C	S	.	.			trans	136	148.4	178.8	0	0	0	0	0	112	S415	S415-G417 PolarHBondContact O-N 2.62Å
418	K	90.3	Very high	86.2	Confident	74 Å²	74	62.6 Å²	62.6	32%	0.322	34%	0.338	S	S	.	.			trans	-93.5	150.7	177.8	-59.4	176.2	-168.5	131.9	0	110.6	R420 E421 Y422	K418-R420 PolarHBondContact O-N 3.27Å; K418-E421 HydrophobicContact CB-CG 4.22Å; K418-E421 WeakPolarHBondContact CD-OE1 3.48Å; K418-E421 PolarHBondContact N-OE2 2.93Å; K418-E421 IonicContact NZ-OE1 2.68Å; K418-E421 WeakPolarHBondContact O-CB 3.45Å; K418-E421 PolarHBondContact O-N 2.98Å; K418-Y422 VanDerWaalsContact O-CD2 3.23Å; K418-Y422 WeakPolarHBondContact O-CD2 3.39Å; K418-Y422 PolarHBondContact O-N 3.43Å
419	I	93.3	Very high	86.7	Confident	150 Å²	150	61.3 Å²	61.3	77%	0.769	33%	0.331	S	S	*	.	H	α-helix	trans	-52.8	-41	175.8	-62.6	171.4	0	0	0	111.5	E421 Y422 L423	I419-E421 VanDerWaalsContact C-N 3.3Å; I419-E421 PolarHBondContact O-N 3.46Å; I419-Y422 PolarHBondContact O-N 3.23Å; I419-L423 PolarHBondContact O-N 3.37Å
420	R	93.7	Very high	87.3	Confident	32 Å²	32	59.5 Å²	59.5	12%	0.121	31%	0.312	C	S	.	.	H	α-helix	trans	-53.6	-44.4	174.5	178.2	-166.5	65.2	124	-5.5	112.9	L74 A75 E77 E323 K418 L423 L424	L74-R420 HydrophobicContact CD2-CG 4.39Å; L74-R420 WeakPolarHBondContact O-CD 3.3Å; L74-R420 PolarHBondContact O-NH1 3.13Å; A75-R420 PolarHBondContact O-NH1 3.23Å; E77-R420 VanDerWaalsContact CB-CZ 3.44Å; E77-R420 IonicContact OE2-CZ 3.52Å; E77-R420 IonicContact OE2-NE 3.03Å; E77-R420 PolarHBondContact OE2-NE 3.36Å; E77-R420 IonicContact OE2-NH1 2.83Å; E77-R420 IonicContact OE2-NH2 3.59Å; E77-R420 PolarHBondContact OE2-NH2 3.24Å; E323-R420 IonicContact OE2-NH2 3.91Å; K418-R420 PolarHBondContact O-N 3.27Å; R420-L423 PolarHBondContact O-N 3.02Å; R420-L424 WeakPolarHBondContact O-CB 3.31Å; R420-L424 PolarHBondContact O-N 3.15Å
421	E	94.9	Very high	87.9	Confident	6 Å²	6	58.1 Å²	58.1	3%	0.028	29%	0.294	C	S	.	.	H	α-helix	trans	-68.5	-41.8	-176.7	-65.4	158.6	-164.2	0	0	109.7	V320 R324 M343 K418 I419 L424 M425	V320-E421 HydrophobicContact CG2-CB 4.31Å; V320-E421 HydrophobicContact CG2-CG 3.98Å; R324-E421 IonicContact CZ-OE2 3.88Å; R324-E421 IonicContact NH2-OE2 2.73Å; R324-E421 PolarHBondContact NH2-OE2 3.09Å; M343-E421 HydrophobicContact CE-CB 3.35Å; M343-E421 HydrophobicContact CE-CG 4.4Å; M343-E421 WeakPolarHBondContact CE-OE2 3.26Å; K418-E421 HydrophobicContact CB-CG 4.22Å; K418-E421 WeakPolarHBondContact CD-OE1 3.48Å; K418-E421 PolarHBondContact N-OE2 2.93Å; K418-E421 IonicContact NZ-OE1 2.68Å; K418-E421 WeakPolarHBondContact O-CB 3.45Å; K418-E421 PolarHBondContact O-N 2.98Å; I419-E421 VanDerWaalsContact C-N 3.3Å; I419-E421 PolarHBondContact O-N 3.46Å; E421-L424 PolarHBondContact O-N 3.06Å; E421-M425 VanDerWaalsContact O-CG 3.31Å; E421-M425 WeakPolarHBondContact O-CG 3.45Å; E421-M425 PolarHBondContact O-N 3.44Å
422	Y	95.4	Very high	88.8	Confident	53 Å²	53	56.8 Å²	56.8	21%	0.208	29%	0.286	C	S	.	.	H	α-helix	trans	-63.1	-42.5	173.8	-64.6	-61.6	0	0	0	112.8	S342 M343 W346 S416 K418 I419 L424 M425 L426	S342-Y422 WeakPolarHBondContact CB-OH 3.11Å; S342-Y422 PolarHBondContact OG-OH 3.35Å; M343-Y422 HydrophobicContact CE-CD1 3.76Å; M343-Y422 HydrophobicContact CE-CD2 4.29Å; M343-Y422 HydrophobicContact CE-CE1 3.49Å; M343-Y422 VanDerWaalsContact CE-CE1 3.49Å; M343-Y422 HydrophobicContact CE-CE2 4.03Å; M343-Y422 HydrophobicContact CE-CG 4.16Å; M343-Y422 HydrophobicContact CG-CE1 3.93Å; M343-Y422 HydrophobicContact SD-CD1 3.92Å; M343-Y422 HydrophobicContact SD-CE1 3.52Å; M343-Y422 VanDerWaalsContact SD-CE1 3.52Å; W346-Y422 AromaticContact CD1-CD1 3.81Å; W346-Y422 AromaticContact NE1-CD1 3.45Å; S416-Y422 PolarHBondContact O-OH 3.32Å; K418-Y422 VanDerWaalsContact O-CD2 3.23Å; K418-Y422 WeakPolarHBondContact O-CD2 3.39Å; K418-Y422 PolarHBondContact O-N 3.43Å; I419-Y422 PolarHBondContact O-N 3.23Å; Y422-L424 VanDerWaalsContact C-N 3.33Å; Y422-L424 PolarHBondContact O-N 2.91Å; Y422-M425 PolarHBondContact O-N 3.46Å; Y422-L426 WeakPolarHBondContact O-CB 3.31Å; Y422-L426 PolarHBondContact O-N 2.99Å
423	L	96	Very high	89.9	Confident	80 Å²	80	48.8 Å²	48.8	42%	0.419	26%	0.257	S	S	.	.	H	α-helix	trans	-61.7	-43	175.7	179.9	129.4	0	0	0	111.1	L74 I419 R420 M425 L426 L427	L74-L423 HydrophobicContact CD1-CD2 3.65Å; L74-L423 HydrophobicContact CD2-CD2 4.06Å; I419-L423 PolarHBondContact O-N 3.37Å; R420-L423 PolarHBondContact O-N 3.02Å; L423-M425 PolarHBondContact O-N 3.09Å; L423-L426 PolarHBondContact O-N 3.09Å; L423-L427 HydrophobicContact CD2-CD1 3.66Å; L423-L427 HydrophobicContact CG-CD1 4.1Å; L423-L427 WeakPolarHBondContact O-CB 3.25Å; L423-L427 VanDerWaalsContact O-CG 3.26Å; L423-L427 WeakPolarHBondContact O-CG 3.34Å; L423-L427 PolarHBondContact O-N 3.19Å
424	L	96.6	Very high	91.3	Very high	2 Å²	2	50.8 Å²	50.8	1%	0.01	26%	0.263	C	S	.	.	H	α-helix	trans	-60	-47.1	175.3	-176.2	156.9	0	0	0	111.2	L71 L74 A75 C316 R420 E421 Y422 L426 L427 H428	L71-L424 HydrophobicContact CD2-CG 4.48Å; L74-L424 HydrophobicContact CB-CD1 4.1Å; A75-L424 HydrophobicContact CB-CD1 3.62Å; C316-L424 HydrophobicContact CB-CD2 3.52Å; C316-L424 VanDerWaalsContact SG-CD1 3.51Å; C316-L424 WeakPolarHBondContact SG-CD2 3.23Å; R420-L424 WeakPolarHBondContact O-CB 3.31Å; R420-L424 PolarHBondContact O-N 3.15Å; E421-L424 PolarHBondContact O-N 3.06Å; Y422-L424 VanDerWaalsContact C-N 3.33Å; Y422-L424 PolarHBondContact O-N 2.91Å; L424-L426 PolarHBondContact O-N 2.9Å; L424-L427 PolarHBondContact O-N 3.31Å; L424-H428 WeakPolarHBondContact CD2-CE1 3.27Å; L424-H428 WeakPolarHBondContact CD2-ND1 3.29Å; L424-H428 PolarHBondContact O-N 3.17Å; L424-H428 PolarHBondContact O-ND1 3.34Å
425	M	96.1	Very high	92.5	Very high	1 Å²	1	46.9 Å²	46.9	1%	0.005	25%	0.248	C	C	.	.	H	α-helix	trans	-63	-43.7	180	-63.8	-39.8	-55.2	0	0	112.2	C316 L317 W346 L350 E421 Y422 L423 L427 H428 W429	C316-M425 HydrophobicContact CB-SD 4.41Å; L317-M425 HydrophobicContact CD1-CE 3.79Å; L317-M425 HydrophobicContact CD2-CE 3.58Å; L317-M425 HydrophobicContact CD2-CG 4.12Å; L317-M425 HydrophobicContact CD2-SD 3.66Å; L317-M425 HydrophobicContact CG-CE 3.34Å; L317-M425 HydrophobicContact CG-SD 3.83Å; W346-M425 HydrophobicContact CB-CB 4.2Å; W346-M425 HydrophobicContact CB-CG 4.15Å; W346-M425 HydrophobicContact CD2-CB 3.69Å; W346-M425 HydrophobicContact CD2-CG 4.5Å; W346-M425 HydrophobicContact CE3-CB 3.89Å; W346-M425 HydrophobicContact CG-CB 3.83Å; W346-M425 HydrophobicContact CG-CG 4.12Å; L350-M425 HydrophobicContact CD1-CE 3.11Å; L350-M425 HydrophobicContact CG-CE 4.2Å; E421-M425 VanDerWaalsContact O-CG 3.31Å; E421-M425 WeakPolarHBondContact O-CG 3.45Å; E421-M425 PolarHBondContact O-N 3.44Å; Y422-M425 PolarHBondContact O-N 3.46Å; L423-M425 PolarHBondContact O-N 3.09Å; M425-L427 VanDerWaalsContact C-N 3.32Å; M425-L427 PolarHBondContact O-N 3.49Å; M425-H428 PolarHBondContact O-N 3.28Å; M425-W429 PolarHBondContact O-N 3.46Å; M425-W429 VanDerWaalsContact O-N 3.07Å
426	L	96.8	Very high	93.1	Very high	72 Å²	72	46 Å²	46	38%	0.377	24%	0.238	S	C	.	.	H	α-helix	trans	-56.9	-46	175.6	-176	82.6	0	0	0	111.1	W346 Y422 L423 L424 H428 W429 L430	W346-L426 HydrophobicContact CH2-CB 4.09Å; W346-L426 HydrophobicContact CH2-CD1 3.68Å; W346-L426 HydrophobicContact CZ2-CD1 4.4Å; Y422-L426 WeakPolarHBondContact O-CB 3.31Å; Y422-L426 PolarHBondContact O-N 2.99Å; L423-L426 PolarHBondContact O-N 3.09Å; L424-L426 PolarHBondContact O-N 2.9Å; L426-H428 VanDerWaalsContact C-N 3.26Å; L426-H428 PolarHBondContact O-N 3.31Å; L426-W429 PolarHBondContact O-N 2.98Å; L426-L430 WeakPolarHBondContact O-CB 3.49Å; L426-L430 PolarHBondContact O-N 3.28Å
427	L	96.5	Very high	93.6	Very high	33 Å²	33	49.4 Å²	49.4	17%	0.173	25%	0.25	C	C	.	.	H	α-helix	trans	-69.5	-17.3	-178.4	-69.7	172.4	0	0	0	114.3	F29 W67 L71 L74 L423 L424 M425 P431	F29-L427 HydrophobicContact CE1-CD1 4.09Å; F29-L427 HydrophobicContact CZ-CD1 3.86Å; W67-L427 HydrophobicContact CH2-CD2 4.02Å; W67-L427 HydrophobicContact CZ2-CB 4.16Å; W67-L427 HydrophobicContact CZ2-CD2 3.76Å; W67-L427 PolarHBondContact NE1-O 3.39Å; L71-L427 HydrophobicContact CD2-CB 3.54Å; L71-L427 HydrophobicContact CD2-CD1 3.79Å; L71-L427 HydrophobicContact CD2-CG 4.33Å; L74-L427 HydrophobicContact CD1-CD1 3.94Å; L423-L427 HydrophobicContact CD2-CD1 3.66Å; L423-L427 HydrophobicContact CG-CD1 4.1Å; L423-L427 WeakPolarHBondContact O-CB 3.25Å; L423-L427 VanDerWaalsContact O-CG 3.26Å; L423-L427 WeakPolarHBondContact O-CG 3.34Å; L423-L427 PolarHBondContact O-N 3.19Å; L424-L427 PolarHBondContact O-N 3.31Å; M425-L427 VanDerWaalsContact C-N 3.32Å; M425-L427 PolarHBondContact O-N 3.49Å; L427-P431 WeakPolarHBondContact O-CD 3.23Å; L427-P431 VanDerWaalsContact O-CG 3.22Å; L427-P431 WeakPolarHBondContact O-CG 3.45Å
428	H	95.9	Very high	93.7	Very high	0 Å²	0	53.6 Å²	53.6	0%	0	26%	0.263	C	S	.	.	H	α-helix	trans	-84.2	-43.9	169.2	-71.5	79.4	0	0	0	111.4	M217 L309 S312 G313 L424 M425 L426	M217-H428 WeakPolarHBondContact CE-NE2 3.41Å; L309-H428 PolarHBondContact O-CD2 3.16Å; S312-H428 PolarHBondContact OG-CD2 3.06Å; S312-H428 VanDerWaalsContact OG-CD2 3.23Å; S312-H428 PolarHBondContact OG-NE2 3.04Å; G313-H428 PolarHBondContact N-CD2 3.45Å; G313-H428 VanDerWaalsContact N-CD2 3.25Å; L424-H428 WeakPolarHBondContact CD2-CE1 3.27Å; L424-H428 WeakPolarHBondContact CD2-ND1 3.29Å; L424-H428 PolarHBondContact O-N 3.17Å; L424-H428 PolarHBondContact O-ND1 3.34Å; M425-H428 PolarHBondContact O-N 3.28Å; L426-H428 VanDerWaalsContact C-N 3.26Å; L426-H428 PolarHBondContact O-N 3.31Å
429	W	94.9	Very high	93.6	Very high	72 Å²	72	51.8 Å²	51.8	27%	0.273	26%	0.259	S	S	.	.	H	α-helix	trans	-75	-41	-173.6	-177.5	83.7	0	0	0	113.1	W346 L349 L350 M425 L426 L432 N433	W346-W429 HydrophobicContact CE3-CB 4.44Å; W346-W429 HydrophobicContact CZ3-CB 3.96Å; W346-W429 HydrophobicContact CZ3-CD2 4.26Å; W346-W429 HydrophobicContact CZ3-CE3 4.4Å; W346-W429 HydrophobicContact CZ3-CG 4.11Å; L349-W429 HydrophobicContact CD1-CD2 4.4Å; L349-W429 HydrophobicContact CD1-CZ2 4.21Å; L349-W429 HydrophobicContact CD2-CZ2 4.04Å; L350-W429 HydrophobicContact CD2-CB 4.44Å; M425-W429 PolarHBondContact O-N 3.46Å; M425-W429 VanDerWaalsContact O-N 3.07Å; L426-W429 PolarHBondContact O-N 2.98Å; W429-L432 PolarHBondContact O-N 3.07Å; W429-N433 WeakPolarHBondContact CZ2-ND2 3.08Å; W429-N433 PolarHBondContact NE1-ND2 2.86Å; W429-N433 VanDerWaalsContact NE1-ND2 3.15Å; W429-N433 PolarHBondContact O-N 3.47Å
430	L	95	Very high	93.2	Very high	69 Å²	69	50.9 Å²	50.9	36%	0.361	25%	0.252	S	S	.	.	H	α-helix	trans	-62.2	-49.4	-175.8	178.1	157.8	0	0	0	112.2	L426 L432 N433 L434	L426-L430 WeakPolarHBondContact O-CB 3.49Å; L426-L430 PolarHBondContact O-N 3.28Å; L430-L432 VanDerWaalsContact C-N 3.32Å; L430-L432 PolarHBondContact O-N 3.4Å; L430-N433 PolarHBondContact O-N 3.12Å; L430-L434 HydrophobicContact CD2-CD1 3.3Å; L430-L434 HydrophobicContact CD2-CG 4.08Å; L430-L434 HydrophobicContact CG-CD1 3.75Å; L430-L434 HydrophobicContact CG-CG 4.19Å; L430-L434 WeakPolarHBondContact O-CB 3.02Å; L430-L434 WeakPolarHBondContact O-CG 3.43Å; L430-L434 PolarHBondContact O-N 3.04Å
431	P	93.5	Very high	92.6	Very high	18 Å²	18	49.7 Å²	49.7	12%	0.117	25%	0.249	C	C	.	.	H	α-helix	trans	-62.2	-38.6	176.3	-22.9	34.3	0	0	0	112.6	W67 L309 L427 N433 L434 L435	W67-P431 HydrophobicContact CZ2-CG 3.64Å; L309-P431 HydrophobicContact CD1-CB 4Å; L427-P431 WeakPolarHBondContact O-CD 3.23Å; L427-P431 VanDerWaalsContact O-CG 3.22Å; L427-P431 WeakPolarHBondContact O-CG 3.45Å; P431-N433 VanDerWaalsContact C-N 3.25Å; P431-N433 PolarHBondContact O-N 3.49Å; P431-L434 PolarHBondContact O-N 3.34Å; P431-L435 VanDerWaalsContact O-CB 3.26Å; P431-L435 WeakPolarHBondContact O-CB 3.38Å; P431-L435 WeakPolarHBondContact O-CG 3.46Å; P431-L435 PolarHBondContact O-N 3.43Å
432	L	93.4	Very high	91.8	Very high	0 Å²	0	49.9 Å²	49.9	0%	0	25%	0.249	C	C	.	.	H	α-helix	trans	-58.7	-37.3	-178.8	-172.8	153	0	0	0	112.4	L309 C310 A353 T360 W429 L430	L309-L432 HydrophobicContact CB-CD1 4.36Å; L309-L432 HydrophobicContact CD1-CB 4.4Å; C310-L432 HydrophobicContact CB-CD1 3.76Å; A353-L432 HydrophobicContact CB-CD1 4.12Å; A353-L432 HydrophobicContact CB-CD2 3.98Å; T360-L432 HydrophobicContact CG2-CD2 3.81Å; W429-L432 PolarHBondContact O-N 3.07Å; L430-L432 VanDerWaalsContact C-N 3.32Å; L430-L432 PolarHBondContact O-N 3.4Å
433	N	93.1	Very high	91.2	Very high	30 Å²	30	47.9 Å²	47.9	16%	0.16	24%	0.242	C	C	.	.	H	α-helix	trans	-91.2	-35.5	179.8	-67.1	-16	0	0	0	113.4	W429 L430 P431	W429-N433 WeakPolarHBondContact CZ2-ND2 3.08Å; W429-N433 PolarHBondContact NE1-ND2 2.86Å; W429-N433 VanDerWaalsContact NE1-ND2 3.15Å; W429-N433 PolarHBondContact O-N 3.47Å; L430-N433 PolarHBondContact O-N 3.12Å; P431-N433 VanDerWaalsContact C-N 3.25Å; P431-N433 PolarHBondContact O-N 3.49Å
434	L	92.5	Very high	90.5	Very high	97 Å²	97	48.3 Å²	48.3	51%	0.508	24%	0.244	S	C	.	.	H	α-helix	trans	-69.5	-34.8	179	-72	-172.7	0	0	0	112.7	L430 P431 I436 L437	L430-L434 HydrophobicContact CD2-CD1 3.3Å; L430-L434 HydrophobicContact CD2-CG 4.08Å; L430-L434 HydrophobicContact CG-CD1 3.75Å; L430-L434 HydrophobicContact CG-CG 4.19Å; L430-L434 WeakPolarHBondContact O-CB 3.02Å; L430-L434 WeakPolarHBondContact O-CG 3.43Å; L430-L434 PolarHBondContact O-N 3.04Å; P431-L434 PolarHBondContact O-N 3.34Å; L434-I436 PolarHBondContact O-N 3.35Å; L434-I436 VanDerWaalsContact O-N 3.12Å; L434-L437 HydrophobicContact CD2-CD1 4.26Å; L434-L437 WeakPolarHBondContact O-CB 3.46Å; L434-L437 PolarHBondContact O-N 3.2Å; L434-L437 VanDerWaalsContact O-N 3.12Å
435	L	90.7	Very high	89.8	Confident	43 Å²	43	48.8 Å²	48.8	23%	0.225	25%	0.246	C	C	.	.	G	3₁₀ helix	trans	-62.1	-21.8	-177.1	-76	176.5	0	0	0	113.6	I305 L309 L361 P431 L437 K438 S439 F442	I305-L435 HydrophobicContact CG2-CD1 4.39Å; L309-L435 HydrophobicContact CD1-CD1 4.34Å; L361-L435 HydrophobicContact CD1-CB 4.22Å; P431-L435 VanDerWaalsContact O-CB 3.26Å; P431-L435 WeakPolarHBondContact O-CB 3.38Å; P431-L435 WeakPolarHBondContact O-CG 3.46Å; P431-L435 PolarHBondContact O-N 3.43Å; L435-L437 VanDerWaalsContact C-N 3.29Å; L435-L437 PolarHBondContact O-N 3.09Å; L435-K438 CarbonylContact O-C 3.53Å; L435-K438 PolarHBondContact O-N 3.29Å; L435-S439 PolarHBondContact O-N 3.01Å; L435-F442 HydrophobicContact CB-CE2 3.95Å; L435-F442 HydrophobicContact CD1-CE2 4.19Å; L435-F442 HydrophobicContact CD1-CZ 4Å; L435-F442 HydrophobicContact CD2-CE2 3.83Å; L435-F442 HydrophobicContact CD2-CZ 3.82Å; L435-F442 HydrophobicContact CG-CE2 4.19Å; L435-F442 HydrophobicContact CG-CZ 4.34Å
436	I	91.7	Very high	88.9	Confident	37 Å²	37	54.3 Å²	54.3	19%	0.19	28%	0.275	C	S	.	.	G	3₁₀ helix	trans	-66.5	-33.7	178.2	-59.4	161.4	0	0	0	111.5	P359 L361 L434 K438 S439	P359-I436 WeakPolarHBondContact O-CD1 2.92Å; L361-I436 HydrophobicContact CB-CG1 4Å; L361-I436 HydrophobicContact CD1-CG1 3.99Å; L434-I436 PolarHBondContact O-N 3.35Å; L434-I436 VanDerWaalsContact O-N 3.12Å; I436-K438 PolarHBondContact O-N 3.06Å; I436-S439 WeakPolarHBondContact O-CB 3.44Å; I436-S439 PolarHBondContact O-N 2.98Å; I436-S439 VanDerWaalsContact O-N 3.17Å
437	L	89.9	Confident	88.5	Confident	151 Å²	151	53.5 Å²	53.5	79%	0.791	27%	0.27	S	S	*	.	G	3₁₀ helix	trans	-61.8	-25	179.1	-62.8	174.9	0	0	0	112	L434 L435	L434-L437 HydrophobicContact CD2-CD1 4.26Å; L434-L437 WeakPolarHBondContact O-CB 3.46Å; L434-L437 PolarHBondContact O-N 3.2Å; L434-L437 VanDerWaalsContact O-N 3.12Å; L435-L437 VanDerWaalsContact C-N 3.29Å; L435-L437 PolarHBondContact O-N 3.09Å
438	K	88.2	Confident	88.1	Confident	105 Å²	105	54.5 Å²	54.5	46%	0.457	28%	0.275	S	S	.	.	G	3₁₀ helix	trans	-121.6	48.2	175	-162	-179.2	177.6	179.7	0	110.8	F41 L435 I436 E440 S441	F41-K438 VanDerWaalsContact CE2-NZ 3.27Å; L435-K438 CarbonylContact O-C 3.53Å; L435-K438 PolarHBondContact O-N 3.29Å; I436-K438 PolarHBondContact O-N 3.06Å; K438-E440 PolarHBondContact O-N 3.26Å; K438-E440 VanDerWaalsContact O-N 3.13Å; K438-S441 PolarHBondContact O-N 3.39Å; K438-S441 PolarHBondContact O-OG 3.26Å; K438-S441 VanDerWaalsContact O-OG 3.08Å
439	S	87.4	Confident	87.7	Confident	36 Å²	36	57.6 Å²	57.6	25%	0.252	29%	0.29	S	S	.	.	T	Hydrogen-bonded Turn	trans	-58.9	-24.4	-177.7	57.4	0	0	0	0	114	L435 I436 S441 F442 M443	L435-S439 PolarHBondContact O-N 3.01Å; I436-S439 WeakPolarHBondContact O-CB 3.44Å; I436-S439 PolarHBondContact O-N 2.98Å; I436-S439 VanDerWaalsContact O-N 3.17Å; S439-S441 PolarHBondContact O-N 3.29Å; S439-F442 PolarHBondContact O-N 3.39Å; S439-M443 WeakPolarHBondContact O-CG 3.45Å; S439-M443 PolarHBondContact O-N 3.26Å
440	E	85.3	Confident	87.2	Confident	132 Å²	132	56.7 Å²	56.7	62%	0.617	29%	0.291	S	S	*	.	H	α-helix	trans	-47.1	-38.8	176.4	-65.9	176	-177.2	0	0	113	K438 F442 M443 L444	K438-E440 PolarHBondContact O-N 3.26Å; K438-E440 VanDerWaalsContact O-N 3.13Å; E440-F442 PolarHBondContact O-N 3.21Å; E440-F442 VanDerWaalsContact O-N 3.13Å; E440-M443 PolarHBondContact O-N 2.89Å; E440-L444 PolarHBondContact O-N 3.31Å; E440-L444 VanDerWaalsContact O-N 3.11Å
441	S	80.6	Confident	86.8	Confident	7 Å²	7	55.9 Å²	55.9	5%	0.049	29%	0.287	C	S	.	.	H	α-helix	trans	-67.6	-13.8	-178.1	61.4	0	0	0	0	115	F41 M56 K438 S439	F41-S441 VanDerWaalsContact CD1-CB 3.42Å; M56-S441 VanDerWaalsContact CE-CA 3.44Å; M56-S441 VanDerWaalsContact CE-O 3.27Å; M56-S441 WeakPolarHBondContact CE-O 3.19Å; M56-S441 WeakPolarHBondContact CG-O 3.31Å; K438-S441 PolarHBondContact O-N 3.39Å; K438-S441 PolarHBondContact O-OG 3.26Å; K438-S441 VanDerWaalsContact O-OG 3.08Å; S439-S441 PolarHBondContact O-N 3.29Å
442	F	79.4	Confident	86.3	Confident	9 Å²	9	58.5 Å²	58.5	4%	0.039	30%	0.298	C	S	.	.	H	α-helix	trans	-114.2	-20.5	178	-52.7	-67.3	0	0	0	111.7	Y301 T302 I305 L361 L435 S439 E440	Y301-F442 HydrophobicContact CD1-CB 4.11Å; Y301-F442 HydrophobicContact CD1-CD1 4.31Å; Y301-F442 WeakPolarHBondContact CD1-O 3.39Å; Y301-F442 HydrophobicContact CE1-CB 4.16Å; Y301-F442 AromaticContact CE1-CD1 3.64Å; Y301-F442 HydrophobicContact CE1-CD1 3.64Å; Y301-F442 HydrophobicContact CE1-CG 4.4Å; T302-F442 HydrophobicContact CG2-CB 3.51Å; I305-F442 HydrophobicContact CD1-CD1 3.26Å; I305-F442 HydrophobicContact CD1-CE1 3.32Å; I305-F442 HydrophobicContact CD1-CG 4.3Å; I305-F442 HydrophobicContact CD1-CZ 4.38Å; L361-F442 HydrophobicContact CD1-CD2 4.36Å; L435-F442 HydrophobicContact CB-CE2 3.95Å; L435-F442 HydrophobicContact CD1-CE2 4.19Å; L435-F442 HydrophobicContact CD1-CZ 4Å; L435-F442 HydrophobicContact CD2-CE2 3.83Å; L435-F442 HydrophobicContact CD2-CZ 3.82Å; L435-F442 HydrophobicContact CG-CE2 4.19Å; L435-F442 HydrophobicContact CG-CZ 4.34Å; S439-F442 PolarHBondContact O-N 3.39Å; E440-F442 PolarHBondContact O-N 3.21Å; E440-F442 VanDerWaalsContact O-N 3.13Å
443	M	82.8	Confident	85.8	Confident	12 Å²	12	62.6 Å²	62.6	6%	0.059	32%	0.319	C	S	.	.	H	α-helix	trans	-86	-34.3	-178.5	-64.9	-42.8	-53.7	0	0	114	Y294 C298 T302 L364 Y368 S439 E440	Y294-M443 PolarHBondContact OH-O 3.07Å; C298-M443 HydrophobicContact CB-CE 3.65Å; C298-M443 PolarHBondContact SG-O 2.72Å; T302-M443 HydrophobicContact CG2-SD 3.35Å; T302-M443 WeakPolarHBondContact CG2-SD 3.13Å; L364-M443 HydrophobicContact CD2-CE 4.28Å; L364-M443 HydrophobicContact CD2-CG 4.24Å; L364-M443 HydrophobicContact CD2-SD 3.24Å; L364-M443 WeakPolarHBondContact CD2-SD 3.39Å; Y368-M443 HydrophobicContact CD1-CE 3.32Å; Y368-M443 HydrophobicContact CD2-CE 4.09Å; Y368-M443 HydrophobicContact CE1-CE 2.91Å; Y368-M443 HydrophobicContact CE1-SD 4.42Å; Y368-M443 HydrophobicContact CE2-CE 3.73Å; Y368-M443 HydrophobicContact CE2-SD 4.37Å; Y368-M443 HydrophobicContact CG-CE 3.91Å; S439-M443 WeakPolarHBondContact O-CG 3.45Å; S439-M443 PolarHBondContact O-N 3.26Å; E440-M443 PolarHBondContact O-N 2.89Å
444	L	80.6	Confident	85.2	Confident	89 Å²	89	65.2 Å²	65.2	47%	0.466	33%	0.332	S	S	.	.			trans	-108.5	49	-168.6	-61.2	177.8	0	0	0	112.5	N43 Y294 E440	N43-L444 PolarHBondContact ND2-O 3.17Å; N43-L444 VanDerWaalsContact ND2-O 3.15Å; N43-L444 PolarHBondContact OD1-O 3.38Å; Y294-L444 WeakPolarHBondContact OH-CD2 3.33Å; E440-L444 PolarHBondContact O-N 3.31Å; E440-L444 VanDerWaalsContact O-N 3.11Å
445	W	81.2	Confident	84.6	Confident	12 Å²	12	62.5 Å²	62.5	5%	0.045	32%	0.317	C	S	.	.			trans	-88.9	-20.6	-174	74	-24.4	0	0	0	116.1	M56 L57 L232 L297 C298 Y301	M56-W445 HydrophobicContact CB-CB 4.48Å; M56-W445 HydrophobicContact CG-CB 4.24Å; M56-W445 WeakPolarHBondContact SD-CA 3.5Å; M56-W445 HydrophobicContact SD-CB 3.51Å; M56-W445 VanDerWaalsContact SD-CB 3.51Å; L57-W445 HydrophobicContact CB-CE3 4.3Å; L57-W445 HydrophobicContact CD1-CE3 4.03Å; L57-W445 HydrophobicContact CD1-CH2 4.49Å; L57-W445 HydrophobicContact CD1-CZ3 4Å; L57-W445 HydrophobicContact CD2-CE3 3.35Å; L57-W445 HydrophobicContact CD2-CH2 3.88Å; L57-W445 HydrophobicContact CD2-CZ3 2.94Å; L57-W445 HydrophobicContact CG-CD2 4.05Å; L57-W445 HydrophobicContact CG-CE3 3.2Å; L57-W445 HydrophobicContact CG-CH2 4.27Å; L57-W445 HydrophobicContact CG-CZ3 3.34Å; L232-W445 HydrophobicContact CD1-CH2 3.3Å; L232-W445 HydrophobicContact CD1-CZ2 4.41Å; L232-W445 HydrophobicContact CD1-CZ3 3.79Å; L232-W445 HydrophobicContact CD2-CH2 3.31Å; L232-W445 HydrophobicContact CD2-CZ2 3.62Å; L232-W445 HydrophobicContact CD2-CZ3 4.48Å; L232-W445 HydrophobicContact CG-CH2 3.85Å; L297-W445 HydrophobicContact CB-CZ2 3.89Å; L297-W445 WeakPolarHBondContact O-CZ2 3.34Å; C298-W445 PolarHBondContact SG-NE1 3.11Å; C298-W445 VanDerWaalsContact SG-NE1 3.38Å; Y301-W445 HydrophobicContact CD1-CD2 4.16Å; Y301-W445 AromaticContact CD1-CE3 3.44Å; Y301-W445 HydrophobicContact CD1-CE3 3.44Å; Y301-W445 VanDerWaalsContact CD1-CE3 3.44Å; Y301-W445 AromaticContact CD1-CZ3 3.88Å; Y301-W445 HydrophobicContact CD1-CZ3 3.88Å; Y301-W445 AromaticContact CD2-CE3 3.67Å; Y301-W445 HydrophobicContact CD2-CE3 3.67Å; Y301-W445 HydrophobicContact CD2-CH2 4.32Å; Y301-W445 AromaticContact CD2-CZ3 3.29Å; Y301-W445 HydrophobicContact CD2-CZ3 3.29Å; Y301-W445 AromaticContact CE1-CE3 3.93Å; Y301-W445 HydrophobicContact CE1-CE3 3.93Å; Y301-W445 HydrophobicContact CE2-CE3 4.12Å; Y301-W445 HydrophobicContact CE2-CZ3 4.04Å; Y301-W445 HydrophobicContact CG-CD2 4.22Å; Y301-W445 AromaticContact CG-CE3 3.28Å; Y301-W445 HydrophobicContact CG-CE3 3.28Å; Y301-W445 HydrophobicContact CG-CH2 4.07Å; Y301-W445 AromaticContact CG-CZ3 3.18Å; Y301-W445 HydrophobicContact CG-CZ3 3.18Å
446	L	77.6	Confident	84.1	Confident	117 Å²	117	64.3 Å²	64.3	61%	0.613	33%	0.325	S	S	*	.			trans	-101.8	0	172.5	-72.9	163	0	0	0	105	N43 Y294 L297	N43-L446 PolarHBondContact ND2-O 3.31Å; Y294-L446 HydrophobicContact CD2-CB 4.22Å; Y294-L446 HydrophobicContact CD2-CD1 4.17Å; Y294-L446 HydrophobicContact CE2-CB 3.89Å; L297-L446 HydrophobicContact CB-CD1 3.81Å; L297-L446 HydrophobicContact CD1-CD1 3.59Å; L297-L446 HydrophobicContact CG-CD1 4.35Å

Retrieved 446 of 446 residues in 443.8 ms (Link to these results)

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