A0A075TSG1_HUMAN Loading...

MLL/FLNA fusion protein

AlphaFold DB , UniProt , Accession A0A075TSG1, Species HUMAN (Homo sapiens, Human), Gene FLNA fusion, Length 46 aa.

						>A0A075TSG1_HUMAN|A0A075TSG1|FLNA fusion
LLGRLRQGNCLNLRGGGCSEPRLHHCTLVVGPAEADIDFDIIRNDN
					

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(Predicted Aligned Error values between residue pairs)

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Site	Residue	pLDDT	pLDDT confidence	pLDDT₁₀	pLDDT10 confidence	SASA	SASA [Å²]	SASA₁₀	SASA10 [Å²]	RSA	RSA unformatted	RSA₁₀	RSA10 unformatted	Surface	Surface10 (not used)	Disorder (not used)	Disorder	Sec. str.	Secondary structure	Isomer	Phi (φ)	Psi (ψ)	Omega (ω)	Chi 1 (χ₁)	Chi 2 (χ₂)	Chi 3 (χ₃)	Chi 4 (χ₄)	Chi 5 (χ₅)	Tau (τ)	Contacts (colored by PAE)	Contact details
1	L	48.5	Very low	54.9	Low	218 Å²	218	154 Å²	154	100%	1.141	80%	0.802	S	S	*	*				0	110.8	0	-83.6	142.2	0	0	0	108.3
2	L	54.8	Low	54.5	Low	177 Å²	177	150.3 Å²	150.3	93%	0.927	78%	0.784	S	S	*	*			trans	41.5	119.8	155.2	-68.9	148.3	0	0	0	119.7
3	G	55.8	Low	54.3	Low	70 Å²	70	149.5 Å²	149.5	72%	0.722	78%	0.78	S	S	*	*			trans	137.6	48.4	144.1	0	0	0	0	0	117.6	L5	G3-L5 PolarHBondContact O-N 3.39Å
4	R	58.8	Low	54.2	Low	245 Å²	245	156.4 Å²	156.4	93%	0.925	79%	0.791	S	S	*	*			trans	-65.2	74.7	153.6	-68.7	173.2	89.5	-165.5	8.4	107.9	R6	R4-R6 PolarHBondContact O-N 2.91Å
5	L	58.1	Low	54.1	Low	169 Å²	169	150.3 Å²	150.3	89%	0.885	78%	0.783	S	S	*	*			trans	-80.8	85.3	169.6	-153.6	80.5	0	0	0	106.8	G3 Q7	G3-L5 PolarHBondContact O-N 3.39Å; L5-Q7 PolarHBondContact O-N 2.96Å
6	R	61.3	Low	54.3	Low	204 Å²	204	145.4 Å²	145.4	77%	0.77	78%	0.78	S	S	*	*			trans	-37.3	111.8	172.2	-64.4	161.1	64.4	-131.4	0	108.4	R4 G8	R4-R6 PolarHBondContact O-N 2.91Å; R6-G8 PolarHBondContact O-N 3.46Å
7	Q	55.6	Low	54.3	Low	192 Å²	192	140.5 Å²	140.5	90%	0.897	77%	0.771	S	S	*	*	S	Bend	trans	-68.7	44.1	159.2	-163.7	178.1	-8.3	0	0	109.5	L5	L5-Q7 PolarHBondContact O-N 2.96Å
8	G	52.7	Low	54.1	Low	36 Å²	36	138.3 Å²	138.3	37%	0.371	77%	0.767	S	S	.	*			trans	-121.7	49	-177.6	0	0	0	0	0	109.1	R6	R6-G8 PolarHBondContact O-N 3.46Å
9	N	54.5	Low	54.3	Low	118 Å²	118	137 Å²	137	63%	0.631	77%	0.768	S	S	*	*	S	Bend	trans	-152.9	6	160.4	-154.3	48.5	0	0	0	116.1	N12	N9-N12 PolarHBondContact OD1-ND2 2.75Å
10	C	53.4	Low	54.2	Low	111 Å²	111	138.2 Å²	138.2	75%	0.75	77%	0.767	S	S	*	*	S	Bend	trans	-106	-0	168.5	-68.6	0	0	0	0	113.3
11	L	50.8	Low	54.3	Low	154 Å²	154	136.3 Å²	136.3	81%	0.806	76%	0.761	S	S	*	*	S	Bend	trans	-97.8	15.7	164.5	-66.1	177.2	0	0	0	112.4	L13	L11-L13 PolarHBondContact O-N 3Å
12	N	49.9	Very low	54.6	Low	109 Å²	109	136 Å²	136	58%	0.583	75%	0.745	S	S	*	*			trans	-90	28.2	161.4	-69.1	-40.3	0	0	0	111.4	N9 R14	N9-N12 PolarHBondContact OD1-ND2 2.75Å; N12-R14 PolarHBondContact O-N 3.01Å; N12-R14 VanDerWaalsContact O-N 3.15Å
13	L	51.6	Low	54.6	Low	141 Å²	141	134.7 Å²	134.7	74%	0.738	74%	0.738	S	S	*	*			trans	-72.4	19.3	155.8	-71.5	171.4	0	0	0	112	L11 G15 G16	L11-L13 PolarHBondContact O-N 3Å; L13-G15 PolarHBondContact O-N 2.8Å; L13-G16 PolarHBondContact O-N 2.91Å
14	R	52.5	Low	54.5	Low	246 Å²	246	138.9 Å²	138.9	93%	0.928	74%	0.739	S	S	*	*	T	Hydrogen-bonded Turn	trans	-70.7	41.1	146.7	-159.5	168.4	-174	-146.9	-1.2	111.4	N12	N12-R14 PolarHBondContact O-N 3.01Å; N12-R14 VanDerWaalsContact O-N 3.15Å
15	G	52.8	Low	54.1	Low	65 Å²	65	135.6 Å²	135.6	67%	0.67	73%	0.733	S	S	*	*	T	Hydrogen-bonded Turn	trans	-128.5	7.6	158.8	0	0	0	0	0	110.7	L13 G17	L13-G15 PolarHBondContact O-N 2.8Å; G15-G17 PolarHBondContact O-N 3.36Å
16	G	57.3	Low	53.8	Low	72 Å²	72	131.3 Å²	131.3	74%	0.742	72%	0.717	S	S	*	*			trans	-88.1	29.4	170.4	0	0	0	0	0	112.5	L13	L13-G16 PolarHBondContact O-N 2.91Å
17	G	55.5	Low	53.1	Low	61 Å²	61	127.5 Å²	127.5	63%	0.629	72%	0.716	S	S	*	*	S	Bend	trans	-123.5	94.7	177.2	0	0	0	0	0	108.3	G15	G15-G17 PolarHBondContact O-N 3.36Å
18	C	50.9	Low	53.2	Low	101 Å²	101	125.5 Å²	125.5	68%	0.682	71%	0.711	S	S	*	*			trans	53.8	108.1	176	-76.2	0	0	0	0	115	E20	C18-E20 PolarHBondContact O-N 3.09Å; C18-E20 VanDerWaalsContact O-N 3.08Å
19	S	57.4	Low	53.3	Low	114 Å²	114	129.2 Å²	129.2	80%	0.797	73%	0.726	S	S	*	*			trans	-34.3	120.3	140.5	-53.2	0	0	0	0	107.5
20	E	52.9	Low	53.8	Low	160 Å²	160	130.8 Å²	130.8	75%	0.748	74%	0.74	S	S	*	*			trans	-43.5	133.8	175.8	-63	111	104.7	0	0	107.2	C18 R22	C18-E20 PolarHBondContact O-N 3.09Å; C18-E20 VanDerWaalsContact O-N 3.08Å; E20-R22 PolarHBondContact O-N 3.08Å
21	P	54.8	Low	53.8	Low	99 Å²	99	127.9 Å²	127.9	64%	0.643	73%	0.729	S	S	*	*			trans	-55.7	107.5	167.6	22.8	-28.1	0	0	0	103.7	L23	P21-L23 PolarHBondContact O-N 2.88Å
22	R	55.3	Low	53.7	Low	212 Å²	212	126.2 Å²	126.2	80%	0.8	73%	0.727	S	S	*	*			trans	-55.6	102.3	170.3	-81.5	178.2	156.6	-156.3	-5	102.3	E20 H24	E20-R22 PolarHBondContact O-N 3.08Å; R22-H24 HydrophobicContact CB-CB 4.16Å; R22-H24 PolarHBondContact O-N 3.15Å
23	L	55	Low	54.1	Low	150 Å²	150	125.7 Å²	125.7	79%	0.785	74%	0.738	S	S	*	*			trans	-68.3	41	172	-66.6	172.7	0	0	0	109.1	P21 H25	P21-L23 PolarHBondContact O-N 2.88Å; L23-H25 VanDerWaalsContact C-N 3.3Å
24	H	53.6	Low	54.3	Low	158 Å²	158	126.6 Å²	126.6	73%	0.731	74%	0.738	S	S	*	*			trans	-88.2	-2	-179.5	-93.8	-86.4	0	0	0	111.5	R22	R22-H24 HydrophobicContact CB-CB 4.16Å; R22-H24 PolarHBondContact O-N 3.15Å
25	H	49.5	Very low	54.5	Low	175 Å²	175	118.4 Å²	118.4	81%	0.81	72%	0.723	S	S	*	*	S	Bend	trans	-134.9	32.4	-176	-139.8	-70.8	0	0	0	115.1	L23	L23-H25 VanDerWaalsContact C-N 3.3Å
26	C	51.6	Low	54.7	Low	80 Å²	80	122.5 Å²	122.5	54%	0.541	73%	0.73	S	S	.	*			trans	-113.3	79	158.2	-68.2	0	0	0	0	108.7	L28	C26-L28 PolarHBondContact O-N 2.91Å
27	T	48.1	Very low	54.8	Low	123 Å²	123	123.6 Å²	123.6	76%	0.755	72%	0.718	S	S	*	*			trans	-64.3	98	145.9	-56	0	0	0	0	105.2	V29	T27-V29 PolarHBondContact O-N 2.68Å; T27-V29 HydrophobicContact CG2-CG2 3.9Å
28	L	56.3	Low	54.7	Low	150 Å²	150	126.7 Å²	126.7	79%	0.785	72%	0.72	S	S	*	*			trans	-63.6	85.2	165.7	-81.1	160.6	0	0	0	106.7	C26 V30	C26-L28 PolarHBondContact O-N 2.91Å; L28-V30 PolarHBondContact O-N 2.73Å
29	V	55.8	Low	55	Low	114 Å²	114	129.9 Å²	129.9	69%	0.691	72%	0.722	S	S	*	*			trans	-66.3	116.7	166.4	172.8	0	0	0	0	105.3	T27 G31	T27-V29 PolarHBondContact O-N 2.68Å; T27-V29 HydrophobicContact CG2-CG2 3.9Å; V29-G31 PolarHBondContact O-N 3.32Å
30	V	64.1	Low	54.9	Low	151 Å²	151	130 Å²	130	92%	0.915	71%	0.714	S	S	*	*			trans	-63.2	105.6	178.7	98.6	0	0	0	0	108.3	L28	L28-V30 PolarHBondContact O-N 2.73Å
31	G	53.8	Low	55.1	Low	51 Å²	51	130.1 Å²	130.1	53%	0.526	72%	0.718	S	S	.	*			trans	156.5	168.6	176.9	0	0	0	0	0	113.4	V29	V29-G31 PolarHBondContact O-N 3.32Å
32	P	49.4	Very low	55.3	Low	118 Å²	118	131.7 Å²	131.7	77%	0.766	72%	0.72	S	S	*	*				-68	175	-82.1	36.7	-31	0	0	0	112.8	E34	P32-E34 PolarHBondContact O-N 2.85Å
33	A	58.2	Low	55.6	Low	98 Å²	98	132.1 Å²	132.1	81%	0.81	72%	0.721	S	S	*	*	S	Bend	trans	-62.2	8	-167.9	0	0	0	0	0	117.7
34	E	55.4	Low	55.4	Low	161 Å²	161	131.7 Å²	131.7	75%	0.752	72%	0.72	S	S	*	*			trans	-137.2	52.3	-171	-54.3	-64.7	151.1	0	0	110.2	P32 D36	P32-E34 PolarHBondContact O-N 2.85Å; E34-D36 PolarHBondContact O-N 2.7Å
35	A	57.5	Low	55.5	Low	73 Å²	73	131.9 Å²	131.9	60%	0.603	73%	0.726	S	S	*	*			trans	-85.6	85.7	163.2	0	0	0	0	0	107.7	I37	A35-I37 HydrophobicContact CB-CG1 4.32Å; A35-I37 PolarHBondContact O-N 2.81Å
36	D	57.3	Low	55.7	Low	151 Å²	151	134.4 Å²	134.4	81%	0.807	75%	0.746	S	S	*	*			trans	-64.8	86.8	159.1	-85.4	-34.5	0	0	0	107	E34 D38	E34-D36 PolarHBondContact O-N 2.7Å; D36-D38 PolarHBondContact O-N 2.96Å
37	I	59.5	Low	55.9	Low	96 Å²	96	137.2 Å²	137.2	49%	0.492	76%	0.756	S	S	.	*			trans	-70.2	90.3	169.2	-56.7	176.4	0	0	0	105.1	A35 F39	A35-I37 HydrophobicContact CB-CG1 4.32Å; A35-I37 PolarHBondContact O-N 2.81Å; I37-F39 HydrophobicContact CB-CE2 4.18Å; I37-F39 PolarHBondContact O-N 3.24Å; I37-F39 WeakPolarHBondContact O-CD2 3.37Å; I37-F39 HydrophobicContact CG2-CZ 4.35Å; I37-F39 HydrophobicContact CG2-CE2 3.63Å; I37-F39 HydrophobicContact CG2-CD2 3.77Å; I37-F39 HydrophobicContact CB-CD2 4.27Å; I37-F39 VanDerWaalsContact C-N 3.34Å
38	D	52.4	Low	56.3	Low	125 Å²	125	137.9 Å²	137.9	67%	0.668	76%	0.756	S	S	*	*			trans	-64.6	98.7	174.6	-129.5	-26.6	0	0	0	107.7	D36 D40	D36-D38 PolarHBondContact O-N 2.96Å; D38-D40 PolarHBondContact O-N 2.79Å; D38-D40 VanDerWaalsContact O-N 3.09Å
39	F	56.2	Low	56.3	Low	168 Å²	168	137.2 Å²	137.2	74%	0.737	75%	0.754	S	S	*	*			trans	-72.5	8.1	179.7	-96.5	-88.5	0	0	0	112.4	I37 I41	I37-F39 HydrophobicContact CB-CE2 4.18Å; I37-F39 PolarHBondContact O-N 3.24Å; I37-F39 WeakPolarHBondContact O-CD2 3.37Å; I37-F39 HydrophobicContact CG2-CZ 4.35Å; I37-F39 HydrophobicContact CG2-CE2 3.63Å; I37-F39 HydrophobicContact CG2-CD2 3.77Å; I37-F39 HydrophobicContact CB-CD2 4.27Å; I37-F39 VanDerWaalsContact C-N 3.34Å; F39-I41 PolarHBondContact O-N 3.02Å
40	D	55.8	Low	56.3	Low	118 Å²	118	138.6 Å²	138.6	63%	0.631	76%	0.758	S	S	*	*			trans	-94.4	31.8	-167.1	-80.4	-18.5	0	0	0	115.3	D38 I42	D38-D40 PolarHBondContact O-N 2.79Å; D38-D40 VanDerWaalsContact O-N 3.09Å; D40-I42 VanDerWaalsContact C-N 3.29Å
41	I	58	Low	55.9	Low	161 Å²	161	137.8 Å²	137.8	83%	0.826	75%	0.748	S	S	*	*	S	Bend	trans	-89.2	12.3	169.5	-51.2	178.7	0	0	0	112.4	F39	F39-I41 PolarHBondContact O-N 3.02Å
42	I	57.8	Low	56	Low	133 Å²	133	143.6 Å²	143.6	68%	0.682	76%	0.763	S	S	*	*	S	Bend	trans	-140.2	70.7	170.8	-42.6	176.8	0	0	0	111.2	D40	D40-I42 VanDerWaalsContact C-N 3.29Å
43	R	63.1	Low	56.5	Low	221 Å²	221	145.4 Å²	145.4	83%	0.834	76%	0.763	S	S	*	*			trans	-147.9	98.9	145.8	-94.6	-160.7	-166.4	85.5	2.5	110.6
44	N	50.5	Low	56.3	Low	141 Å²	141	149.1 Å²	149.1	75%	0.754	76%	0.759	S	S	*	*			trans	-160.2	87.2	137.5	-163	-24.8	0	0	0	109.8
45	D	55.6	Low	56.4	Low	161 Å²	161	148.1 Å²	148.1	86%	0.861	76%	0.76	S	S	*	*			trans	-135.6	117	158.8	-70.5	-62.5	0	0	0	107.5
46	N	53.2	Low	56.3	Low	229 Å²	229	154.9 Å²	154.9	100%	1.225	77%	0.774	S	S	*	*			trans	-62.8	0	178.3	179.2	11.5	0	0	0	112.3

Retrieved 46 of 46 residues in 33.4 ms (Link to these results)

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