A0A077YVJ4_TRITR Loading...

fumarate reductase (NADH)

AlphaFold DB , UniProt , Accession A0A077YVJ4, Species TRITR (Trichuris trichiura, Whipworm), Gene n/a, Length 532 aa.

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Site Residue pLDDT pLDDT confidence pLDDT10 pLDDT10 confidence SASA SASA [Ų] SASA10 SASA10 [Ų] RSA RSA unformatted RSA10 RSA10 unformatted Surface Surface10 (not used) Disorder (not used) Disorder Sec. str. Secondary structure Isomer Phi (φ) Psi (ψ) Omega (ω) Chi 1 (χ1) Chi 2 (χ2) Chi 3 (χ3) Chi 4 (χ4) Chi 5 (χ5) Tau (τ) Contacts (colored by PAE) Contact details
1M47.9Very low44.8Very low221 Ų221118 Ų118100%1.08962%0.623SS**  0-31.30-74-179.9177.400114.1R3M1-R3 PolarHBondContact O-N 2.98Å
2G45.1Very low44.9Very low54 Ų54115.6 Ų115.656%0.55761%0.61SS**Hα-helixtrans-62.7-34.4-177.300000117.2V6G2-V6 WeakPolarHBondContact O-CG2 3.26Å; G2-V6 PolarHBondContact O-N 2.78Å
3R43.9Very low44.5Very low224 Ų224113.8 Ų113.885%0.84560%0.6SS**Hα-helixtrans-70.2-35.2-178.2-77.4-173.6175.1-174.3-1.2114.3M1 Q7M1-R3 PolarHBondContact O-N 2.98Å; R3-Q7 PolarHBondContact O-N 3.17Å
4F45.8Very low44.3Very low165 Ų165115 Ų11572%0.72460%0.598SS**Hα-helixtrans-73.8-36.8179.7-81-78.8000112.7V6 Q7 A8F4-V6 VanDerWaalsContact C-N 3.35Å; F4-Q7 PolarHBondContact O-N 2.92Å; F4-A8 PolarHBondContact O-N 3.4Å; F4-A8 VanDerWaalsContact O-N 3.08Å
5A44.7Very low44Very low64 Ų64110.3 Ų110.353%0.52958%0.579SS.*Hα-helixtrans-65.5-38.9177.200000111.9A8 L9A5-A8 PolarHBondContact O-N 3.33Å; A5-L9 WeakPolarHBondContact O-CB 3.34Å; A5-L9 PolarHBondContact O-N 2.84Å
6V43.4Very low43.6Very low85 Ų85116.8 Ų116.852%0.51559%0.593SS.*Hα-helixtrans-67.6-40.5178.1175.10000111.4G2 F4 L9 L10G2-V6 WeakPolarHBondContact O-CG2 3.26Å; G2-V6 PolarHBondContact O-N 2.78Å; F4-V6 VanDerWaalsContact C-N 3.35Å; V6-L9 PolarHBondContact O-N 2.95Å; V6-L10 HydrophobicContact CG1-CD1 3.72Å; V6-L10 HydrophobicContact CG1-CG 4.49Å; V6-L10 VanDerWaalsContact O-CB 3.32Å; V6-L10 WeakPolarHBondContact O-CB 3.48Å; V6-L10 WeakPolarHBondContact O-CD1 3.31Å; V6-L10 WeakPolarHBondContact O-CG 3.23Å; V6-L10 PolarHBondContact O-N 3.08Å
7Q42.4Very low43.1Very low114 Ų114117.7 Ų117.753%0.53360%0.599SS.*Hα-helixtrans-65.3-42.6175.1-81.7-176.9-26.700112.8R3 F4 L10 M11R3-Q7 PolarHBondContact O-N 3.17Å; F4-Q7 PolarHBondContact O-N 2.92Å; Q7-L10 PolarHBondContact O-N 3.34Å; Q7-M11 WeakPolarHBondContact O-CG 3.24Å; Q7-M11 PolarHBondContact O-N 2.74Å
8A47.5Very low42.8Very low51 Ų51116.1 Ų116.142%0.42159%0.592SS.*Hα-helixtrans-66.6-39.517800000112.3F4 A5 M11 L12F4-A8 PolarHBondContact O-N 3.4Å; F4-A8 VanDerWaalsContact O-N 3.08Å; A5-A8 PolarHBondContact O-N 3.33Å; A8-M11 PolarHBondContact O-N 2.89Å; A8-L12 WeakPolarHBondContact O-CG 3.35Å; A8-L12 PolarHBondContact O-N 3.37Å; A8-L12 VanDerWaalsContact O-N 3.09Å
9L42.4Very low42.6Very low108 Ų108115.9 Ų115.957%0.56560%0.596SS**Hα-helixtrans-69.6-39.3177.7-160.979.3000111.7A5 V6 L12 L13A5-L9 WeakPolarHBondContact O-CB 3.34Å; A5-L9 PolarHBondContact O-N 2.84Å; V6-L9 PolarHBondContact O-N 2.95Å; L9-L12 PolarHBondContact O-N 3.16Å; L9-L13 HydrophobicContact CD2-CD1 4.23Å; L9-L13 HydrophobicContact CG-CD1 4.04Å; L9-L13 WeakPolarHBondContact O-CB 3.46Å; L9-L13 PolarHBondContact O-N 3.12Å
10L43.8Very low41.9Very low86 Ų86118.7 Ų118.745%0.4561%0.607SS.*Hα-helixtrans-61.9-44.9173.1-81.5161.1000111V6 Q7 L12 L13 F14V6-L10 HydrophobicContact CG1-CD1 3.72Å; V6-L10 HydrophobicContact CG1-CG 4.49Å; V6-L10 VanDerWaalsContact O-CB 3.32Å; V6-L10 WeakPolarHBondContact O-CB 3.48Å; V6-L10 WeakPolarHBondContact O-CD1 3.31Å; V6-L10 WeakPolarHBondContact O-CG 3.23Å; V6-L10 PolarHBondContact O-N 3.08Å; Q7-L10 PolarHBondContact O-N 3.34Å; L10-L12 VanDerWaalsContact C-N 3.29Å; L10-L12 PolarHBondContact O-N 2.78Å; L10-L13 PolarHBondContact O-N 3.26Å; L10-F14 HydrophobicContact CD2-CD2 4.47Å; L10-F14 HydrophobicContact CD2-CE2 4.17Å; L10-F14 WeakPolarHBondContact O-CB 3.47Å; L10-F14 VanDerWaalsContact O-CD2 3.31Å; L10-F14 WeakPolarHBondContact O-CD2 3.4Å; L10-F14 PolarHBondContact O-N 3.15Å
11M46.5Very low41.6Very low126 Ų126116.9 Ų116.962%0.62161%0.605SS**Hα-helixtrans-60.8-36.8175.7-72.6-173.6-153.300112.8Q7 A8 S15Q7-M11 WeakPolarHBondContact O-CG 3.24Å; Q7-M11 PolarHBondContact O-N 2.74Å; A8-M11 PolarHBondContact O-N 2.89Å; M11-S15 PolarHBondContact O-N 2.85Å; M11-S15 VanDerWaalsContact O-N 3.07Å
12L45.2Very low41Very low89 Ų89111.5 Ų111.547%0.46658%0.584SS.*Hα-helixtrans-74.9-33.2177.8-76.1162.9000113.8A8 L9 L10 S15 R16A8-L12 WeakPolarHBondContact O-CG 3.35Å; A8-L12 PolarHBondContact O-N 3.37Å; A8-L12 VanDerWaalsContact O-N 3.09Å; L9-L12 PolarHBondContact O-N 3.16Å; L10-L12 VanDerWaalsContact C-N 3.29Å; L10-L12 PolarHBondContact O-N 2.78Å; L12-S15 PolarHBondContact O-OG 2.95Å; L12-R16 PolarHBondContact O-N 2.85Å
13L40.6Very low40.3Very low93 Ų93117.7 Ų117.749%0.48760%0.596SS.*Hα-helixtrans-74.8-39.6175.8-84.3158.2000111.2L9 L10 S15 R16 L17L9-L13 HydrophobicContact CD2-CD1 4.23Å; L9-L13 HydrophobicContact CG-CD1 4.04Å; L9-L13 WeakPolarHBondContact O-CB 3.46Å; L9-L13 PolarHBondContact O-N 3.12Å; L10-L13 PolarHBondContact O-N 3.26Å; L13-S15 VanDerWaalsContact C-N 3.32Å; L13-R16 PolarHBondContact O-N 2.85Å; L13-L17 PolarHBondContact O-N 3.09Å
14F40.6Very low40Very low130 Ų130109.9 Ų109.957%0.5758%0.575SS**Hα-helixtrans-63.8-37.7172.3-90.3-81.6000111.5L10 R16 L18L10-F14 HydrophobicContact CD2-CD2 4.47Å; L10-F14 HydrophobicContact CD2-CE2 4.17Å; L10-F14 WeakPolarHBondContact O-CB 3.47Å; L10-F14 VanDerWaalsContact O-CD2 3.31Å; L10-F14 WeakPolarHBondContact O-CD2 3.4Å; L10-F14 PolarHBondContact O-N 3.15Å; F14-R16 PolarHBondContact O-N 2.88Å; F14-L18 HydrophobicContact CD1-CD1 3.82Å; F14-L18 WeakPolarHBondContact O-CB 3.31Å; F14-L18 WeakPolarHBondContact O-CD1 3.35Å; F14-L18 PolarHBondContact O-N 3.4Å
15S40.4Very low39.9Very low45 Ų45106.2 Ų106.232%0.31556%0.563SS.*Hα-helixtrans-66.3-35176.970.10000113.3M11 L12 L13 V19M11-S15 PolarHBondContact O-N 2.85Å; M11-S15 VanDerWaalsContact O-N 3.07Å; L12-S15 PolarHBondContact O-OG 2.95Å; L13-S15 VanDerWaalsContact C-N 3.32Å; S15-V19 VanDerWaalsContact O-CG2 3.24Å; S15-V19 WeakPolarHBondContact O-CG2 3.46Å
16R36.8Very low40.3Very low213 Ų213107.7 Ų107.780%0.80457%0.567SS**Hα-helixtrans-76.1-35.4179.1-78.8-171.3175.7-165.9-1.5114.5L12 L13 F14 L18L12-R16 PolarHBondContact O-N 2.85Å; L13-R16 PolarHBondContact O-N 2.85Å; F14-R16 PolarHBondContact O-N 2.88Å; R16-L18 VanDerWaalsContact C-N 3.34Å
17L36.5Very low41.1Very low133 Ų133110.2 Ų110.270%0.69658%0.578SS**Hα-helixtrans-75.3-22.7178.5-88.4151.2000112.8L13L13-L17 PolarHBondContact O-N 3.09Å
18L36.9Very low42.4Very low88 Ų88108 Ų10846%0.46157%0.569SS.*THydrogen-bonded Turntrans-98.59.1-178.4-85.7126.1000115.5F14 R16 Q20 F178F14-L18 HydrophobicContact CD1-CD1 3.82Å; F14-L18 WeakPolarHBondContact O-CB 3.31Å; F14-L18 WeakPolarHBondContact O-CD1 3.35Å; F14-L18 PolarHBondContact O-N 3.4Å; R16-L18 VanDerWaalsContact C-N 3.34Å; L18-Q20 PolarHBondContact O-N 2.91Å; L18-F178 HydrophobicContact CD2-CE2 3.91Å; L18-F178 HydrophobicContact CD2-CZ 4.13Å
19V38.7Very low44.1Very low113 Ų113109.2 Ų109.269%0.68557%0.572SS**  trans-68.53.1166.8-169.70000111.8S15 S21S15-V19 VanDerWaalsContact O-CG2 3.24Å; S15-V19 WeakPolarHBondContact O-CG2 3.46Å; V19-S21 VanDerWaalsContact C-N 3.27Å; V19-S21 PolarHBondContact O-N 2.83Å
20Q30Very low46.4Very low171 Ų171104.4 Ų104.480%0.79955%0.547SS*.SBendtrans-66.588.7165.7-77.9-172.6-1300111L18L18-Q20 PolarHBondContact O-N 2.91Å
21S34.3Very low48.8Very low81 Ų81101.8 Ų101.857%0.56653%0.533SS*.  trans47.678.8155.870.40000116.3V19 K23V19-S21 VanDerWaalsContact C-N 3.27Å; V19-S21 PolarHBondContact O-N 2.83Å; S21-K23 PolarHBondContact O-N 2.89Å
22V36.4Very low51.1Low108 Ų10895.8 Ų95.866%0.65550%0.504SS*.  trans-63.893.4141.9-179.30000105.8S24V22-S24 PolarHBondContact O-N 2.68Å; V22-S24 VanDerWaalsContact O-N 3.15Å
23K30.2Very low53.6Low184 Ų18491.5 Ų91.580%0.848%0.481SS*.  trans-68.9107.7170.6-74.4-175.6177.5179.20106.5S21 D25S21-K23 PolarHBondContact O-N 2.89Å; K23-D25 PolarHBondContact O-N 3.37Å
24S36.6Very low56.4Low60 Ų6087.1 Ų87.142%0.4246%0.458SS..  trans-64.1129.7169.6420000108.5V22 P26V22-S24 PolarHBondContact O-N 2.68Å; V22-S24 VanDerWaalsContact O-N 3.15Å; S24-P26 WeakPolarHBondContact O-CD 3.41Å
25D44.2Very low59.2Low88 Ų8881.2 Ų81.247%0.47143%0.433SS..  trans-72.8116167.1-173.2-15.2000107.2K23 D27 I28K23-D25 PolarHBondContact O-N 3.37Å; D25-D27 PolarHBondContact O-N 3.45Å; D25-D27 VanDerWaalsContact O-N 3.1Å; D25-D27 PolarHBondContact OD1-N 3.17Å; D25-D27 VanDerWaalsContact OD1-N 3.12Å; D25-I28 HydrophobicContact CB-CD1 3.9Å; D25-I28 HydrophobicContact CB-CG1 4Å; D25-I28 PolarHBondContact O-N 3.26Å
26P52.5Low62Low95 Ų9579.6 Ų79.662%0.61742%0.423SS*.THydrogen-bonded Turntrans-61.8-14.7-178.524.8-32.9000113.6S24S24-P26 WeakPolarHBondContact O-CD 3.41Å
27D61.6Low64.9Low139 Ų13969.4 Ų69.474%0.74339%0.385SS*.THydrogen-bonded Turntrans-95.2-4.9-173.2-69.1-22.8000114.9D25 T29D25-D27 PolarHBondContact O-N 3.45Å; D25-D27 VanDerWaalsContact O-N 3.1Å; D25-D27 PolarHBondContact OD1-N 3.17Å; D25-D27 VanDerWaalsContact OD1-N 3.12Å; D27-T29 PolarHBondContact O-N 3.3Å
28I69.5Low67.9Low66 Ų6663.7 Ų63.734%0.33836%0.358SS..  trans-77.3112.8178.4-61.3174.9000109.8D25 N54D25-I28 HydrophobicContact CB-CD1 3.9Å; D25-I28 HydrophobicContact CB-CG1 4Å; D25-I28 PolarHBondContact O-N 3.26Å; I28-N54 HydrophobicContact CG2-CB 4.29Å; I28-N54 WeakPolarHBondContact CG2-OD1 3.38Å
29T83.7Confident70.8Confident78 Ų7859.5 Ų59.548%0.47934%0.336SS..  trans-68.1123.1170.7-59.30000109D27 P221D27-T29 PolarHBondContact O-N 3.3Å; T29-P221 HydrophobicContact CG2-CB 4.3Å; T29-P221 HydrophobicContact CG2-CG 3.97Å; T29-P221 WeakPolarHBondContact CG2-O 3.33Å
30P90.6Very high73.7Confident7 Ų754.4 Ų54.45%0.04531%0.306CS..  trans-68.9142177.728.8-34.6000111.1V32 V33 N54 I220 A222P30-V32 VanDerWaalsContact C-N 3.33Å; P30-V33 HydrophobicContact CB-CG2 4.31Å; P30-V33 HydrophobicContact CG-CG2 3.63Å; P30-N54 CarbonylContact C-O 3.51Å; P30-I220 HydrophobicContact CG-CG2 3.8Å; P30-A222 HydrophobicContact CG-CB 4.34Å; P30-A222 VanDerWaalsContact O-CA 3.31Å; P30-A222 WeakPolarHBondContact O-CA 3.42Å
31D92.9Very high77Confident30 Ų3046.3 Ų46.316%0.1627%0.268CS..SBendtrans-70.7-38.9168.5-52.6-55.7000108.9A53 N54 D223 A224D31-A53 HydrophobicContact CB-CB 4.21Å; D31-N54 PolarHBondContact N-O 3.21Å; D31-N54 WeakPolarHBondContact OD2-CB 3.4Å; D31-N54 PolarHBondContact OD2-N 3.07Å; D31-N54 PolarHBondContact OD2-ND2 3.17Å; D31-D223 WeakPolarHBondContact O-CB 3.5Å; D31-D223 PolarHBondContact O-N 3Å; D31-A224 PolarHBondContact O-N 3.28Å
32V96.2Very high80Confident0 Ų042.4 Ų42.40%024%0.241CC..EExtended strand (participates in β ladder)trans-126.4127.1-178.9-174.20000111.1P30 V34 A48 A53 N54 V55 T56 A224 V226 A500 A501P30-V32 VanDerWaalsContact C-N 3.33Å; V32-V34 HydrophobicContact CG1-CG2 4.1Å; V32-A48 HydrophobicContact CB-CB 4.4Å; V32-A48 HydrophobicContact CG1-CB 4.49Å; V32-A48 HydrophobicContact CG2-CB 4.27Å; V32-A53 HydrophobicContact CG2-CB 4.26Å; V32-N54 PolarHBondContact N-O 3.48Å; V32-V55 VanDerWaalsContact O-CA 3.31Å; V32-V55 WeakPolarHBondContact O-CA 3.35Å; V32-T56 PolarHBondContact O-N 3.36Å; V32-A224 WeakPolarHBondContact CA-O 3.42Å; V32-V226 HydrophobicContact CG1-CG2 3.81Å; V32-A500 HydrophobicContact CG1-CB 3.99Å; V32-A500 HydrophobicContact CG2-CB 4.14Å; V32-A501 HydrophobicContact CG2-CB 4.19Å
33V97.8Very high83Confident0 Ų037.4 Ų37.40%021%0.21CC..EExtended strand (participates in β ladder)trans-101.9128.2165.4168.40000109.6P30 V35 T56 I58 V207 I220 A222 A224 V225 V226P30-V33 HydrophobicContact CB-CG2 4.31Å; P30-V33 HydrophobicContact CG-CG2 3.63Å; V33-V35 HydrophobicContact CG1-CG2 4.06Å; V33-T56 WeakPolarHBondContact CA-O 3.39Å; V33-I58 HydrophobicContact CG1-CD1 3.49Å; V33-I58 VanDerWaalsContact CG1-CD1 3.49Å; V33-I58 HydrophobicContact CG1-CG1 4.38Å; V33-V207 HydrophobicContact CG1-CG1 4.22Å; V33-V207 HydrophobicContact CG1-CG2 3.83Å; V33-I220 HydrophobicContact CG2-CG2 3.74Å; V33-A222 HydrophobicContact CB-CB 4.11Å; V33-A222 HydrophobicContact CG2-CB 3.58Å; V33-A224 PolarHBondContact N-O 3.46Å; V33-V225 HydrophobicContact CB-CG2 4.47Å; V33-V225 CarbonylContact O-C 3.59Å; V33-V225 WeakPolarHBondContact O-CA 3.26Å; V33-V226 PolarHBondContact O-N 3.4Å
34V98.8Very high86.3Confident0 Ų028.6 Ų28.60%017%0.172CC..EExtended strand (participates in β ladder)trans-109.6128.9174.4-176.30000109.1V32 A44 V55 T56 L57 I58 V226 T228V32-V34 HydrophobicContact CG1-CG2 4.1Å; V34-A44 HydrophobicContact CG1-CB 4.15Å; V34-A44 HydrophobicContact CG2-CB 4.28Å; V34-V55 HydrophobicContact CG2-CG1 3.99Å; V34-T56 PolarHBondContact N-O 3.3Å; V34-L57 HydrophobicContact CB-CD1 3.75Å; V34-L57 HydrophobicContact CG1-CD1 3.63Å; V34-I58 PolarHBondContact O-N 3.41Å; V34-V226 WeakPolarHBondContact CA-O 3Å; V34-V226 HydrophobicContact CG1-CB 4.49Å; V34-V226 HydrophobicContact CG2-CB 4.27Å; V34-V226 HydrophobicContact CG2-CG2 4.39Å; V34-T228 HydrophobicContact CG1-CG2 4.48Å; V34-T228 WeakPolarHBondContact CG1-OG1 3.15Å
35V98.8Very high89.2Confident7 Ų725.8 Ų25.84%0.04215%0.152CC..EExtended strand (participates in β ladder)trans-111.7109.6-175.1-171.10000111.2V33 A194 V207 V225 V226 L227 T228 T229 M267V33-V35 HydrophobicContact CG1-CG2 4.06Å; V35-A194 HydrophobicContact CG1-CB 3.51Å; V35-A194 HydrophobicContact CG2-CB 4.16Å; V35-V207 HydrophobicContact CG2-CG1 4.07Å; V35-V225 HydrophobicContact CG2-CG1 4.05Å; V35-V226 PolarHBondContact N-O 3.13Å; V35-L227 HydrophobicContact CB-CD2 4.06Å; V35-L227 HydrophobicContact CG2-CD2 4.1Å; V35-T228 CarbonylContact O-C 2.96Å; V35-T228 WeakPolarHBondContact O-CA 3.28Å; V35-T228 PolarHBondContact O-N 3.19Å; V35-T228 PolarHBondContact O-OG1 3.47Å; V35-T229 HydrophobicContact CB-CG2 4.29Å; V35-T229 HydrophobicContact CG1-CG2 3.72Å; V35-T229 WeakPolarHBondContact O-CG2 3.42Å; V35-T229 PolarHBondContact O-N 3.25Å; V35-M267 HydrophobicContact CG1-CE 4.33Å
36G98.7Very high91.7Very high10 Ų1022.6 Ų22.610%0.10314%0.135CC..  trans102.4115.5-178.300000111.4G38 G41 I58 T228G36-G38 VanDerWaalsContact C-N 3.28Å; G36-G38 PolarHBondContact O-N 2.94Å; G36-G41 WeakPolarHBondContact O-CA 3.22Å; G36-I58 VanDerWaalsContact CA-O 3.31Å; G36-I58 WeakPolarHBondContact CA-O 3.31Å; G36-I58 PolarHBondContact N-O 3.27Å; G36-T228 PolarHBondContact O-OG1 3.16Å
37A98.5Very high93.8Very high0 Ų018.2 Ų18.20%011%0.107CC..  trans-93.236.9-178.400000112.9L57 E59 I64 G65A37-L57 HydrophobicContact CB-CD1 4.06Å; A37-L57 HydrophobicContact CB-CD2 3.81Å; A37-L57 HydrophobicContact CB-CG 3.97Å; A37-E59 WeakPolarHBondContact CA-OE2 3.3Å; A37-E59 HydrophobicContact CB-CB 3.72Å; A37-E59 HydrophobicContact CB-CG 4Å; A37-E59 WeakPolarHBondContact CB-OE2 3.09Å; A37-E59 PolarHBondContact N-OE2 2.89Å; A37-I64 HydrophobicContact CB-CB 3.94Å; A37-I64 HydrophobicContact CB-CG2 3.56Å; A37-G65 WeakPolarHBondContact O-CA 3.45Å; A37-G65 PolarHBondContact O-N 3.41Å
38G98.5Very high95.5Very high13 Ų1311.6 Ų11.613%0.1347%0.071CC..BIsolated β-bridgetrans-67.9-178.2160.400000111.7G36 A40 G41 I42G36-G38 VanDerWaalsContact C-N 3.28Å; G36-G38 PolarHBondContact O-N 2.94Å; G38-A40 VanDerWaalsContact C-N 3.27Å; G38-A40 PolarHBondContact O-N 3.02Å; G38-G41 PolarHBondContact O-N 3.14Å; G38-G41 VanDerWaalsContact O-N 3.14Å; G38-I42 WeakPolarHBondContact O-CG1 3.4Å; G38-I42 PolarHBondContact O-N 2.81Å
39L98.7Very high96.6Very high0 Ų08.6 Ų8.60%06%0.056CC..Hα-helixtrans-58-39.5-178.6-177.860.4000112.5G41 I42 C43 S68 L165 V166 Y169 L486 C489 I490L39-G41 PolarHBondContact O-N 3.1Å; L39-I42 PolarHBondContact O-N 3.39Å; L39-C43 WeakPolarHBondContact O-CB 3.27Å; L39-C43 PolarHBondContact O-N 2.81Å; L39-C43 PolarHBondContact O-SG 2.79Å; L39-S68 VanDerWaalsContact CB-CB 3.47Å; L39-S68 VanDerWaalsContact CB-OG 3.3Å; L39-S68 WeakPolarHBondContact CB-OG 3.22Å; L39-S68 PolarHBondContact N-OG 3.09Å; L39-L165 HydrophobicContact CD1-CB 4.2Å; L39-L165 HydrophobicContact CD2-CB 4.26Å; L39-L165 HydrophobicContact CD2-CD1 4.3Å; L39-V166 HydrophobicContact CB-CG2 4.31Å; L39-Y169 HydrophobicContact CD1-CD2 3.78Å; L39-Y169 HydrophobicContact CD1-CE2 4.45Å; L39-Y169 HydrophobicContact CD1-CG 4.25Å; L39-L486 HydrophobicContact CD2-CB 4.46Å; L39-L486 HydrophobicContact CD2-CD2 3.62Å; L39-C489 HydrophobicContact CB-CB 4.01Å; L39-C489 HydrophobicContact CD2-CB 4.06Å; L39-C489 HydrophobicContact CG-CB 3.97Å; L39-I490 HydrophobicContact CD1-CG1 4.25Å; L39-I490 HydrophobicContact CD2-CD1 4.14Å; L39-I490 HydrophobicContact CD2-CG1 3.87Å; L39-I490 HydrophobicContact CG-CG1 4.02Å
40A98.9Very high97.1Very high6 Ų69.5 Ų9.55%0.056%0.058CC..Hα-helixtrans-62-43.6177.400000112.6G38 C43 A44 T228 C489 G493G38-A40 VanDerWaalsContact C-N 3.27Å; G38-A40 PolarHBondContact O-N 3.02Å; A40-C43 PolarHBondContact O-N 3.16Å; A40-A44 WeakPolarHBondContact O-CB 3.28Å; A40-A44 PolarHBondContact O-N 2.96Å; A40-T228 HydrophobicContact CB-CG2 3.92Å; A40-C489 WeakPolarHBondContact CA-O 3.34Å; A40-C489 HydrophobicContact CB-CB 3.96Å; A40-G493 WeakPolarHBondContact O-CA 3.4Å
41G98.9Very high97.1Very high0 Ų013.7 Ų13.70%08%0.077CC..Hα-helixtrans-69.5-36.5179.200000113.2G36 G38 L39 A44 T45 T228G36-G41 WeakPolarHBondContact O-CA 3.22Å; G38-G41 PolarHBondContact O-N 3.14Å; G38-G41 VanDerWaalsContact O-N 3.14Å; L39-G41 PolarHBondContact O-N 3.1Å; G41-A44 PolarHBondContact O-N 3.49Å; G41-T45 WeakPolarHBondContact O-CB 3.47Å; G41-T45 PolarHBondContact O-N 3.23Å; G41-T45 PolarHBondContact O-OG1 3.1Å; G41-T228 WeakPolarHBondContact CA-OG1 3.32Å
42I98.9Very high96.9Very high0 Ų017.6 Ų17.60%010%0.098CC..Hα-helixtrans-64.1-43.7172.9-62.5166.1000110.1G38 L39 T45 L46 I64 V166 Y170 V173G38-I42 WeakPolarHBondContact O-CG1 3.4Å; G38-I42 PolarHBondContact O-N 2.81Å; L39-I42 PolarHBondContact O-N 3.39Å; I42-T45 WeakPolarHBondContact O-CB 3.25Å; I42-T45 PolarHBondContact O-N 3Å; I42-L46 PolarHBondContact O-N 2.99Å; I42-I64 HydrophobicContact CD1-CD1 4.06Å; I42-V166 HydrophobicContact CD1-CB 4.42Å; I42-V166 HydrophobicContact CD1-CG1 3.75Å; I42-Y170 HydrophobicContact CG2-CD2 4.48Å; I42-V173 HydrophobicContact CG2-CG2 3.93Å; I42-V173 WeakPolarHBondContact O-CG2 3.36Å
43C98.8Very high96.7Very high2 Ų217.9 Ų17.91%0.01410%0.1CC..Hα-helixtrans-67.4-35.5176.5-66.80000112.8L39 A40 L46 G47 Y169L39-C43 WeakPolarHBondContact O-CB 3.27Å; L39-C43 PolarHBondContact O-N 2.81Å; L39-C43 PolarHBondContact O-SG 2.79Å; A40-C43 PolarHBondContact O-N 3.16Å; C43-L46 PolarHBondContact O-N 2.87Å; C43-G47 PolarHBondContact O-N 3.45Å; C43-Y169 VanDerWaalsContact SG-CD1 3.51Å
44A98.8Very high96.4Very high0 Ų019.1 Ų19.10%011%0.107CC..Hα-helixtrans-65.4-42.5172.600000112V34 A40 G41 L46 G47 A48 V226 G493 G497V34-A44 HydrophobicContact CG1-CB 4.15Å; V34-A44 HydrophobicContact CG2-CB 4.28Å; A40-A44 WeakPolarHBondContact O-CB 3.28Å; A40-A44 PolarHBondContact O-N 2.96Å; G41-A44 PolarHBondContact O-N 3.49Å; A44-L46 PolarHBondContact O-N 2.59Å; A44-G47 PolarHBondContact O-N 3.32Å; A44-A48 WeakPolarHBondContact O-CB 3.25Å; A44-A48 PolarHBondContact O-N 2.86Å; A44-V226 HydrophobicContact CB-CG1 4.12Å; A44-G493 WeakPolarHBondContact CA-O 3.4Å; A44-G493 WeakPolarHBondContact CB-O 3.43Å; A44-G493 PolarHBondContact N-O 2.82Å; A44-G497 WeakPolarHBondContact O-CA 3.36Å
45T98.5Very high96.2Very high0 Ų019.2 Ų19.20%011%0.107CC..Hα-helixtrans-58.5-49173.9-59.40000110.7G41 I42 G47 A48 L49 V55 V173 F186G41-T45 WeakPolarHBondContact O-CB 3.47Å; G41-T45 PolarHBondContact O-N 3.23Å; G41-T45 PolarHBondContact O-OG1 3.1Å; I42-T45 WeakPolarHBondContact O-CB 3.25Å; I42-T45 PolarHBondContact O-N 3Å; T45-G47 VanDerWaalsContact C-N 3.35Å; T45-G47 PolarHBondContact O-N 3.09Å; T45-A48 PolarHBondContact O-N 2.99Å; T45-L49 HydrophobicContact CG2-CD1 3.86Å; T45-L49 HydrophobicContact CG2-CG 4.38Å; T45-L49 WeakPolarHBondContact O-CB 3.37Å; T45-L49 VanDerWaalsContact O-CG 3.28Å; T45-L49 WeakPolarHBondContact O-CG 3.31Å; T45-L49 PolarHBondContact O-N 3.06Å; T45-V55 HydrophobicContact CG2-CB 4.5Å; T45-V55 HydrophobicContact CG2-CG1 3.96Å; T45-V173 HydrophobicContact CG2-CG1 3.71Å; T45-V173 HydrophobicContact CG2-CG2 4.02Å; T45-F186 HydrophobicContact CG2-CD2 3.83Å; T45-F186 HydrophobicContact CG2-CE2 3.45Å; T45-F186 VanDerWaalsContact CG2-CE2 3.45Å; T45-F186 HydrophobicContact CG2-CZ 4.24Å
46L97.3Very high96.1Very high22 Ų2219.4 Ų19.412%0.11511%0.109CC..Hα-helixtrans-60.7-43.3176.8-178.160.1000112.2I42 C43 A44 A48 L49 N50 Y169 M172 V173 A176I42-L46 PolarHBondContact O-N 2.99Å; C43-L46 PolarHBondContact O-N 2.87Å; A44-L46 PolarHBondContact O-N 2.59Å; L46-A48 PolarHBondContact O-N 2.82Å; L46-L49 PolarHBondContact O-N 2.88Å; L46-N50 WeakPolarHBondContact O-CB 3.18Å; L46-N50 VanDerWaalsContact O-CG 3.22Å; L46-N50 PolarHBondContact O-N 3.45Å; L46-N50 PolarHBondContact O-ND2 3.12Å; L46-Y169 HydrophobicContact CD2-CD1 3.9Å; L46-Y169 HydrophobicContact CD2-CE1 4.3Å; L46-M172 HydrophobicContact CD1-CB 3.93Å; L46-M172 HydrophobicContact CD2-CB 3.73Å; L46-M172 HydrophobicContact CD2-CG 4.44Å; L46-M172 HydrophobicContact CD2-SD 3.81Å; L46-M172 HydrophobicContact CG-CB 4.48Å; L46-V173 HydrophobicContact CB-CG2 3.8Å; L46-A176 HydrophobicContact CD1-CB 3.9Å
47G96.6Very high96.1Very high2 Ų218.9 Ų18.92%0.02110%0.104CC..Hα-helixtrans-58.9-45.7177.400000112.6C43 A44 T45C43-G47 PolarHBondContact O-N 3.45Å; A44-G47 PolarHBondContact O-N 3.32Å; T45-G47 VanDerWaalsContact C-N 3.35Å; T45-G47 PolarHBondContact O-N 3.09Å
48A95.7Very high96Very high0 Ų019 Ų190%010%0.104CC..Hα-helixtrans-70-42.7178.600000112.6V32 A44 T45 L46 N50 Q51 A53 V55 G497 A501V32-A48 HydrophobicContact CB-CB 4.4Å; V32-A48 HydrophobicContact CG1-CB 4.49Å; V32-A48 HydrophobicContact CG2-CB 4.27Å; A44-A48 WeakPolarHBondContact O-CB 3.25Å; A44-A48 PolarHBondContact O-N 2.86Å; T45-A48 PolarHBondContact O-N 2.99Å; L46-A48 PolarHBondContact O-N 2.82Å; A48-N50 VanDerWaalsContact C-N 3.28Å; A48-N50 PolarHBondContact O-N 3.29Å; A48-Q51 CarbonylContact O-C 3.56Å; A48-Q51 WeakPolarHBondContact O-CA 3.28Å; A48-Q51 WeakPolarHBondContact O-CB 3.49Å; A48-Q51 PolarHBondContact O-N 3.46Å; A48-A53 HydrophobicContact CB-CB 4.32Å; A48-A53 WeakPolarHBondContact O-CB 3.37Å; A48-A53 PolarHBondContact O-N 2.92Å; A48-V55 HydrophobicContact CB-CG2 3.6Å; A48-G497 WeakPolarHBondContact CA-O 3.48Å; A48-G497 WeakPolarHBondContact CB-O 3.4Å; A48-A501 HydrophobicContact CB-CB 4.07Å
49L94.1Very high96Very high4 Ų419 Ų192%0.02110%0.101CC..Hα-helixtrans-61.5-36.1176.3-72.2171.9000112.2T45 L46 Q51 N52 V55 V173 A176 A177 H185 F186T45-L49 HydrophobicContact CG2-CD1 3.86Å; T45-L49 HydrophobicContact CG2-CG 4.38Å; T45-L49 WeakPolarHBondContact O-CB 3.37Å; T45-L49 VanDerWaalsContact O-CG 3.28Å; T45-L49 WeakPolarHBondContact O-CG 3.31Å; T45-L49 PolarHBondContact O-N 3.06Å; L46-L49 PolarHBondContact O-N 2.88Å; L49-Q51 PolarHBondContact O-N 3.4Å; L49-N52 WeakPolarHBondContact O-CA 3.33Å; L49-N52 PolarHBondContact O-N 3.27Å; L49-V55 HydrophobicContact CD2-CB 4.26Å; L49-V55 HydrophobicContact CD2-CG2 3.89Å; L49-V55 HydrophobicContact CG-CB 4.47Å; L49-V55 HydrophobicContact CG-CG2 3.97Å; L49-V173 HydrophobicContact CD1-CG1 3.83Å; L49-A176 HydrophobicContact CB-CB 4.06Å; L49-A176 HydrophobicContact CD1-CB 4.32Å; L49-A177 HydrophobicContact CD1-CB 4.32Å; L49-H185 HydrophobicContact CD2-CB 4.49Å; L49-F186 HydrophobicContact CD1-CB 4.45Å; L49-F186 HydrophobicContact CD1-CD2 4.35Å; L49-F186 HydrophobicContact CD1-CG 4.37Å; L49-F186 HydrophobicContact CD2-CB 4.11Å
50N92.5Very high95.9Very high97 Ų9721.2 Ų21.252%0.51911%0.112SC..THydrogen-bonded Turntrans-67.7-11.8174.6-73.2-20.8000113.5L46 A48L46-N50 WeakPolarHBondContact O-CB 3.18Å; L46-N50 VanDerWaalsContact O-CG 3.22Å; L46-N50 PolarHBondContact O-N 3.45Å; L46-N50 PolarHBondContact O-ND2 3.12Å; A48-N50 VanDerWaalsContact C-N 3.28Å; A48-N50 PolarHBondContact O-N 3.29Å
51Q91.3Very high95.7Very high94 Ų9424.4 Ų24.444%0.43913%0.126SC..THydrogen-bonded Turntrans-97.810.8169.3-59-56.4-47.100112.5A48 L49 A53 V498 A501A48-Q51 CarbonylContact O-C 3.56Å; A48-Q51 WeakPolarHBondContact O-CA 3.28Å; A48-Q51 WeakPolarHBondContact O-CB 3.49Å; A48-Q51 PolarHBondContact O-N 3.46Å; L49-Q51 PolarHBondContact O-N 3.4Å; Q51-A53 VanDerWaalsContact C-N 3.26Å; Q51-A53 PolarHBondContact O-N 3.38Å; Q51-V498 HydrophobicContact CG-CB 4.49Å; Q51-V498 HydrophobicContact CG-CG1 4.25Å; Q51-V498 HydrophobicContact CG-CG2 4.44Å; Q51-A501 HydrophobicContact CB-CB 3.61Å; Q51-A501 HydrophobicContact CG-CB 4.02Å
52N89.8Confident95.5Very high112 Ų11228.5 Ų28.560%0.59915%0.154SC*.THydrogen-bonded Turntrans61.527-176.4-49.9-63.2000114.5L49L49-N52 WeakPolarHBondContact O-CA 3.33Å; L49-N52 PolarHBondContact O-N 3.27Å
53A91Very high95.4Very high6 Ų631.4 Ų31.45%0.0518%0.178CC..  trans-78.2148.117500000111.9D31 V32 A48 Q51 V55 A501D31-A53 HydrophobicContact CB-CB 4.21Å; V32-A53 HydrophobicContact CG2-CB 4.26Å; A48-A53 HydrophobicContact CB-CB 4.32Å; A48-A53 WeakPolarHBondContact O-CB 3.37Å; A48-A53 PolarHBondContact O-N 2.92Å; Q51-A53 VanDerWaalsContact C-N 3.26Å; Q51-A53 PolarHBondContact O-N 3.38Å; A53-V55 HydrophobicContact CB-CG2 4.3Å; A53-A501 HydrophobicContact CB-CB 3.71Å
54N91.7Very high95.4Very high26 Ų2633.5 Ų33.514%0.13919%0.189CC..  trans-71.9119.9161.9-63.1-78.8000109.3I28 P30 D31 V32 H185I28-N54 HydrophobicContact CG2-CB 4.29Å; I28-N54 WeakPolarHBondContact CG2-OD1 3.38Å; P30-N54 CarbonylContact C-O 3.51Å; D31-N54 PolarHBondContact N-O 3.21Å; D31-N54 WeakPolarHBondContact OD2-CB 3.4Å; D31-N54 PolarHBondContact OD2-N 3.07Å; D31-N54 PolarHBondContact OD2-ND2 3.17Å; V32-N54 PolarHBondContact N-O 3.48Å; N54-H185 CarbonylContact C-O 3.53Å; N54-H185 WeakPolarHBondContact CA-O 3.33Å; N54-H185 VanDerWaalsContact CG-ND1 3.27Å; N54-H185 PolarHBondContact OD1-ND1 2.95Å
55V94.8Very high95.3Very high2 Ų233.5 Ų33.51%0.01219%0.189CC..EExtended strand (participates in β ladder)trans-121128.6-175.7-170.30000111.4V32 V34 T45 A48 L49 A53 H185 F186 R187V32-V55 VanDerWaalsContact O-CA 3.31Å; V32-V55 WeakPolarHBondContact O-CA 3.35Å; V34-V55 HydrophobicContact CG2-CG1 3.99Å; T45-V55 HydrophobicContact CG2-CB 4.5Å; T45-V55 HydrophobicContact CG2-CG1 3.96Å; A48-V55 HydrophobicContact CB-CG2 3.6Å; L49-V55 HydrophobicContact CD2-CB 4.26Å; L49-V55 HydrophobicContact CD2-CG2 3.89Å; L49-V55 HydrophobicContact CG-CB 4.47Å; L49-V55 HydrophobicContact CG-CG2 3.97Å; A53-V55 HydrophobicContact CB-CG2 4.3Å; V55-H185 PolarHBondContact N-O 3.17Å; V55-F186 HydrophobicContact CB-CD2 4.46Å; V55-F186 WeakPolarHBondContact O-CA 3.06Å; V55-R187 PolarHBondContact O-N 3.49Å
56T95.8Very high95.2Very high11 Ų1134.4 Ų34.47%0.06720%0.198CC..EExtended strand (participates in β ladder)trans-108.6116.4163.1-65.40000109.5V32 V33 V34 I58 R187 L189 I220V32-T56 PolarHBondContact O-N 3.36Å; V33-T56 WeakPolarHBondContact CA-O 3.39Å; V34-T56 PolarHBondContact N-O 3.3Å; T56-I58 HydrophobicContact CG2-CG1 4.14Å; T56-R187 CarbonylContact C-O 3.58Å; T56-R187 WeakPolarHBondContact CA-O 3.42Å; T56-R187 HydrophobicContact CG2-CB 4.5Å; T56-L189 HydrophobicContact CG2-CD1 3.76Å; T56-L189 HydrophobicContact CG2-CG 4.1Å; T56-I220 HydrophobicContact CG2-CD1 4.5Å
57L98.3Very high95.2Very high0 Ų034.9 Ų34.90%020%0.2CC..EExtended strand (participates in β ladder)trans-94.9124172.7177.259.5000109.6V34 A37 F186 R187 L188 L189V34-L57 HydrophobicContact CB-CD1 3.75Å; V34-L57 HydrophobicContact CG1-CD1 3.63Å; A37-L57 HydrophobicContact CB-CD1 4.06Å; A37-L57 HydrophobicContact CB-CD2 3.81Å; A37-L57 HydrophobicContact CB-CG 3.97Å; L57-F186 HydrophobicContact CB-CE2 3.9Å; L57-F186 HydrophobicContact CB-CZ 4.46Å; L57-R187 PolarHBondContact N-O 3.47Å; L57-L188 HydrophobicContact CB-CD1 4.26Å; L57-L188 HydrophobicContact CD2-CD1 4.03Å; L57-L188 HydrophobicContact CG-CD1 3.93Å; L57-L188 CarbonylContact O-C 3.53Å; L57-L188 WeakPolarHBondContact O-CA 3.4Å; L57-L189 PolarHBondContact O-N 2.98Å
58I97.9Very high95.3Very high1 Ų135.7 Ų35.71%0.00521%0.206CC..EExtended strand (participates in β ladder)trans-107.6133.4-178.7-62.3164.3000109.2V33 V34 G36 T56 L189 T192 V207 V209 I220V33-I58 HydrophobicContact CG1-CD1 3.49Å; V33-I58 VanDerWaalsContact CG1-CD1 3.49Å; V33-I58 HydrophobicContact CG1-CG1 4.38Å; V34-I58 PolarHBondContact O-N 3.41Å; G36-I58 VanDerWaalsContact CA-O 3.31Å; G36-I58 WeakPolarHBondContact CA-O 3.31Å; G36-I58 PolarHBondContact N-O 3.27Å; T56-I58 HydrophobicContact CG2-CG1 4.14Å; I58-L189 CarbonylContact C-O 3.26Å; I58-L189 HydrophobicContact CG1-CB 4.44Å; I58-L189 HydrophobicContact CG1-CD1 4.39Å; I58-T192 HydrophobicContact CG2-CG2 3.95Å; I58-T192 WeakPolarHBondContact CG2-O 3.47Å; I58-V207 HydrophobicContact CD1-CG2 3.76Å; I58-V209 HydrophobicContact CD1-CG1 3.69Å; I58-I220 HydrophobicContact CD1-CD1 4.15Å
59E97.8Very high95.4Very high13 Ų1336.9 Ų36.96%0.06122%0.216CC..  trans-133.7129.2175.5178.747.9-105.400109.4A37 E61 L189 T190 N191 T192A37-E59 WeakPolarHBondContact CA-OE2 3.3Å; A37-E59 HydrophobicContact CB-CB 3.72Å; A37-E59 HydrophobicContact CB-CG 4Å; A37-E59 WeakPolarHBondContact CB-OE2 3.09Å; A37-E59 PolarHBondContact N-OE2 2.89Å; E59-E61 HydrophobicContact CG-CB 4.21Å; E59-E61 PolarHBondContact OE1-N 3.01Å; E59-L189 PolarHBondContact N-O 3.42Å; E59-T190 HydrophobicContact CB-CG2 4.34Å; E59-T190 CarbonylContact O-C 3.56Å; E59-T190 VanDerWaalsContact O-C 3.25Å; E59-T190 VanDerWaalsContact O-CA 3.3Å; E59-T190 WeakPolarHBondContact O-CA 3.24Å; E59-N191 PolarHBondContact O-N 3.07Å; E59-T192 CarbonylContact C-O 3.54Å; E59-T192 VanDerWaalsContact C-O 3.26Å; E59-T192 PolarHBondContact O-N 3.04Å; E59-T192 VanDerWaalsContact O-O 3.11Å
60M95.9Very high95.4Very high48 Ų4841.6 Ų41.624%0.23624%0.236CC..SBendtrans-74.7-31.6179.273.5178.97000111.2N191 T192 A193 V212M60-N191 WeakPolarHBondContact O-CA 3.18Å; M60-T192 WeakPolarHBondContact CA-O 3.49Å; M60-T192 PolarHBondContact N-O 3.06Å; M60-A193 HydrophobicContact CB-CB 4.25Å; M60-V212 WeakPolarHBondContact O-CG1 3.3Å
61E95.6Very high95.5Very high73 Ų7338 Ų3834%0.34122%0.22SC..SBendtrans-79.4165.9177.9-63.4-68.3112.100111.7E59 A63 T190 N191 Y259E59-E61 HydrophobicContact CG-CB 4.21Å; E59-E61 PolarHBondContact OE1-N 3.01Å; E61-A63 PolarHBondContact O-N 2.87Å; E61-T190 WeakPolarHBondContact O-CB 3.44Å; E61-N191 PolarHBondContact O-N 3.08Å; E61-Y259 VanDerWaalsContact CD-CD1 3.48Å; E61-Y259 HydrophobicContact CG-CD1 3.53Å; E61-Y259 HydrophobicContact CG-CE1 4.13Å; E61-Y259 HydrophobicContact CG-CG 4.13Å
62S95.5Very high95.5Very high86 Ų8634.3 Ų34.360%0.60121%0.205SC*.SBendtrans-71.7-13.2174.868.50000113.3N191S62-N191 VanDerWaalsContact CA-OD1 3.32Å; S62-N191 WeakPolarHBondContact CA-OD1 3.45Å; S62-N191 WeakPolarHBondContact CB-OD1 3.4Å; S62-N191 PolarHBondContact N-OD1 3.13Å
63A96.2Very high95.6Very high61 Ų6129.4 Ų29.450%0.50418%0.179SC..SBendtrans-142.1148.3-17600000111.7E61E61-A63 PolarHBondContact O-N 2.87Å
64I98.2Very high95.8Very high46 Ų4629.3 Ų29.324%0.23618%0.178CC..SBendtrans-74.3164.5178.465.3170000112.9A37 I42 V166 Y170 L188A37-I64 HydrophobicContact CB-CB 3.94Å; A37-I64 HydrophobicContact CB-CG2 3.56Å; I42-I64 HydrophobicContact CD1-CD1 4.06Å; I64-V166 HydrophobicContact CD1-CG1 4.17Å; I64-V166 HydrophobicContact CG1-CG1 4.25Å; I64-Y170 HydrophobicContact CD1-CD1 3.94Å; I64-Y170 HydrophobicContact CD1-CD2 3.45Å; I64-Y170 VanDerWaalsContact CD1-CD2 3.45Å; I64-Y170 HydrophobicContact CD1-CE1 4.38Å; I64-Y170 HydrophobicContact CD1-CE2 3.94Å; I64-Y170 HydrophobicContact CD1-CG 3.44Å; I64-Y170 VanDerWaalsContact CD1-CG 3.44Å; I64-L188 HydrophobicContact CG2-CD1 4.22Å; I64-L188 HydrophobicContact CG2-CD2 3.98Å
65G97.6Very high96.1Very high0 Ų028 Ų280%017%0.172CC..BIsolated β-bridgetrans112.5-23.5164.400000115A37 S68 A69A37-G65 WeakPolarHBondContact O-CA 3.45Å; A37-G65 PolarHBondContact O-N 3.41Å; G65-S68 WeakPolarHBondContact O-CB 3.39Å; G65-S68 PolarHBondContact O-N 3.38Å; G65-S68 VanDerWaalsContact O-N 3.13Å; G65-A69 PolarHBondContact O-N 2.85Å
66G96.8Very high96.3Very high18 Ų1828 Ų2819%0.18617%0.171CC..THydrogen-bonded Turntrans46.3-141.5175.800000113.8S68 A69 Y259G66-S68 VanDerWaalsContact C-N 3.25Å; G66-S68 PolarHBondContact O-N 3.46Å; G66-A69 PolarHBondContact O-N 2.96Å; G66-Y259 WeakPolarHBondContact CA-OH 3.45Å; G66-Y259 PolarHBondContact O-OH 2.92Å
67N97.3Very high96.4Very high32 Ų3227.4 Ų27.417%0.17117%0.168CC..THydrogen-bonded Turntrans-67.8-26.3176.2-71.2-35.1000112.7A69 K70 N256 G257 Y259N67-A69 PolarHBondContact O-N 3.47Å; N67-K70 WeakPolarHBondContact O-CB 3.14Å; N67-K70 PolarHBondContact O-N 3.12Å; N67-K70 PolarHBondContact OD1-NZ 2.93Å; N67-N256 PolarHBondContact ND2-OD1 2.95Å; N67-G257 PolarHBondContact OD1-N 3.33Å; N67-Y259 PolarHBondContact N-OH 3.21Å
68S97.9Very high96.4Very high19 Ų1927.4 Ų27.413%0.13317%0.168CC..G310 helixtrans-57.6-39.6177.6-48.10000111.3L39 G65 G66 K70 A71 G162L39-S68 VanDerWaalsContact CB-CB 3.47Å; L39-S68 VanDerWaalsContact CB-OG 3.3Å; L39-S68 WeakPolarHBondContact CB-OG 3.22Å; L39-S68 PolarHBondContact N-OG 3.09Å; G65-S68 WeakPolarHBondContact O-CB 3.39Å; G65-S68 PolarHBondContact O-N 3.38Å; G65-S68 VanDerWaalsContact O-N 3.13Å; G66-S68 VanDerWaalsContact C-N 3.25Å; G66-S68 PolarHBondContact O-N 3.46Å; S68-K70 PolarHBondContact O-N 2.95Å; S68-K70 VanDerWaalsContact O-N 3.16Å; S68-A71 WeakPolarHBondContact O-CB 3.46Å; S68-A71 PolarHBondContact O-N 2.85Å; S68-A71 VanDerWaalsContact O-N 3.13Å; S68-G162 CarbonylContact O-C 3.58Å; S68-G162 WeakPolarHBondContact O-CA 3.37Å
69A96.7Very high96.4Very high26 Ų2631.9 Ų31.922%0.21519%0.189CC..G310 helixtrans-63.1-21.6178.200000113.9G65 G66 N67 K163 V166G65-A69 PolarHBondContact O-N 2.85Å; G66-A69 PolarHBondContact O-N 2.96Å; N67-A69 PolarHBondContact O-N 3.47Å; A69-K163 WeakPolarHBondContact O-CB 3.42Å; A69-K163 PolarHBondContact O-N 2.83Å; A69-V166 HydrophobicContact CB-CG2 4.44Å
70K94.8Very high96.5Very high102 Ų10231.3 Ų31.344%0.44319%0.186SC..G310 helixtrans-86.7-15.1179.4-56.6174-174.9166.10113N67 S68 S72 Y259N67-K70 WeakPolarHBondContact O-CB 3.14Å; N67-K70 PolarHBondContact O-N 3.12Å; N67-K70 PolarHBondContact OD1-NZ 2.93Å; S68-K70 PolarHBondContact O-N 2.95Å; S68-K70 VanDerWaalsContact O-N 3.16Å; K70-S72 PolarHBondContact O-N 3.06Å; K70-Y259 VanDerWaalsContact CE-OH 3.27Å; K70-Y259 WeakPolarHBondContact CE-OH 3.27Å; K70-Y259 PolarHBondContact NZ-OH 2.91Å; K70-Y259 VanDerWaalsContact NZ-OH 3.08Å
71A94.6Very high96.6Very high23 Ų2332.5 Ų32.519%0.1919%0.193CC..  trans-65.2127.3-17400000111.7S68 G162 L486S68-A71 WeakPolarHBondContact O-CB 3.46Å; S68-A71 PolarHBondContact O-N 2.85Å; S68-A71 VanDerWaalsContact O-N 3.13Å; A71-G162 PolarHBondContact O-N 3.37Å; A71-L486 HydrophobicContact CB-CD1 4.01Å; A71-L486 HydrophobicContact CB-CD2 3.99Å; A71-L486 HydrophobicContact CB-CG 4.21Å
72S91.3Very high96.7Very high15 Ų1530.3 Ų30.311%0.10518%0.184CC..  trans-124.6-12.8-170.655.90000114.1K70 R149 P303K70-S72 PolarHBondContact O-N 3.06Å; S72-R149 PolarHBondContact O-NH1 3.2Å; S72-P303 WeakPolarHBondContact OG-CG 3.42Å
73S91.6Very high96.8Very high10 Ų1026.3 Ų26.37%0.0716%0.156CC..SBendtrans-78-38.5-175.2-61.40000114R149 E304S73-R149 VanDerWaalsContact C-NH1 3.26Å; S73-R149 VanDerWaalsContact O-CD 3.31Å; S73-R149 WeakPolarHBondContact O-CD 3.36Å; S73-R149 WeakPolarHBondContact O-CG 3.41Å; S73-R149 PolarHBondContact O-NH1 2.9Å; S73-E304 PolarHBondContact OG-N 3.43Å
74G95.6Very high96.9Very high3 Ų329.2 Ų29.23%0.03116%0.161CC..  trans135.6176.2-178.700000113.4T147 H148 G483 L486G74-T147 VanDerWaalsContact CA-CG2 3.42Å; G74-H148 CarbonylContact C-O 3.45Å; G74-H148 WeakPolarHBondContact CA-O 3.29Å; G74-G483 WeakPolarHBondContact O-CA 3.48Å; G74-L486 WeakPolarHBondContact O-CD1 3.43Å
75I98.3Very high96.8Very high0 Ų034.2 Ų34.20%018%0.183CC..EExtended strand (participates in β ladder)trans-115.8141.8178.6-175.2171.1000109.2V123 L133 T147 H148 I161 L165 L486 I487 I490I75-V123 HydrophobicContact CD1-CG2 4.12Å; I75-V123 HydrophobicContact CG1-CG2 4.23Å; I75-V123 HydrophobicContact CG2-CG2 4.18Å; I75-L133 HydrophobicContact CG2-CD1 4.15Å; I75-T147 CarbonylContact O-C 3.57Å; I75-T147 WeakPolarHBondContact O-CA 3.45Å; I75-H148 HydrophobicContact CG2-CB 4.03Å; I75-H148 PolarHBondContact N-O 3.46Å; I75-H148 PolarHBondContact O-N 2.78Å; I75-I161 HydrophobicContact CB-CD1 4.22Å; I75-I161 HydrophobicContact CG2-CD1 3.71Å; I75-L165 HydrophobicContact CD1-CD1 4.33Å; I75-L486 HydrophobicContact CB-CB 4.17Å; I75-L486 HydrophobicContact CB-CD1 4.31Å; I75-L486 HydrophobicContact CD1-CB 4.23Å; I75-L486 HydrophobicContact CG1-CB 4Å; I75-I487 HydrophobicContact CD1-CB 4.23Å; I75-I487 HydrophobicContact CD1-CD1 4.23Å; I75-I487 HydrophobicContact CG1-CB 3.93Å; I75-I490 HydrophobicContact CD1-CD1 3.51Å
76N98.7Very high96.8Very high0 Ų038 Ų380%021%0.206CC..EExtended strand (participates in β ladder)trans-94.6143.1-178.5-68.1-22.4000112.8F95 H142 R146 T147 G482 G483 N484 I487N76-F95 HydrophobicContact CB-CE1 4.2Å; N76-F95 HydrophobicContact CB-CE2 4.22Å; N76-F95 HydrophobicContact CB-CZ 3.61Å; N76-H142 PolarHBondContact ND2-CE1 2.96Å; N76-R146 WeakPolarHBondContact CA-O 3.35Å; N76-R146 HydrophobicContact CB-CG 3.92Å; N76-T147 WeakPolarHBondContact OD1-CA 3.5Å; N76-T147 WeakPolarHBondContact OD1-CB 3.46Å; N76-T147 PolarHBondContact OD1-OG1 2.8Å; N76-G482 PolarHBondContact ND2-O 3.15Å; N76-G482 PolarHBondContact OD1-O 3.36Å; N76-G483 VanDerWaalsContact ND2-C 3.27Å; N76-N484 PolarHBondContact ND2-N 3.32Å; N76-N484 PolarHBondContact ND2-OD1 3.35Å; N76-I487 HydrophobicContact CB-CG2 4.38Å
77A98.7Very high96.8Very high0 Ų040 Ų400%023%0.227CC..  trans-145.1144.4158.800000112Q83 S119 V123 R146A77-Q83 VanDerWaalsContact O-CD 3.25Å; A77-Q83 PolarHBondContact O-NE2 2.9Å; A77-Q83 PolarHBondContact O-OE1 3.39Å; A77-S119 VanDerWaalsContact CA-OG 3.31Å; A77-S119 WeakPolarHBondContact CA-OG 3.38Å; A77-V123 HydrophobicContact CB-CB 3.82Å; A77-V123 HydrophobicContact CB-CG1 4.24Å; A77-V123 HydrophobicContact CB-CG2 3.63Å; A77-R146 PolarHBondContact N-O 2.66Å; A77-R146 VanDerWaalsContact O-CG 3.29Å; A77-R146 WeakPolarHBondContact O-CG 3.47Å
78C98.5Very high96.8Very high0 Ų040 Ų400%023%0.228CC..SBendtrans-85.3157.3160.8480000109.6S80 Q83 C92 F95 A116 S119 A120C78-S80 PolarHBondContact O-N 2.88Å; C78-Q83 VanDerWaalsContact C-OE1 3.28Å; C78-C92 HydrophobicContact CB-CB 4.11Å; C78-C92 WeakPolarHBondContact CB-SG 3.28Å; C78-C92 WeakPolarHBondContact SG-CA 3.42Å; C78-C92 WeakPolarHBondContact SG-CB 3.04Å; C78-C92 CovalentContact SG-SG 2.08Å; C78-C92 PolarHBondContact SG-SG 2.93Å; C78-F95 HydrophobicContact CB-CB 3.99Å; C78-F95 HydrophobicContact CB-CD1 3.99Å; C78-F95 HydrophobicContact CB-CG 4.46Å; C78-A116 PolarHBondContact SG-O 3.22Å; C78-S119 PolarHBondContact N-OG 3.36Å; C78-S119 VanDerWaalsContact N-OG 3.11Å; C78-S119 PolarHBondContact SG-OG 3Å; C78-A120 WeakPolarHBondContact O-CB 3.4Å
79E98Very high96.8Very high95 Ų9547.8 Ų47.844%0.44426%0.259SS..SBendtrans52.427.3167.1-56.1175.9174.200114.6Q83 D90 T91 C92E79-Q83 VanDerWaalsContact N-OE1 3.15Å; E79-D90 WeakPolarHBondContact CG-O 3.39Å; E79-D90 PolarHBondContact N-O 3.04Å; E79-T91 VanDerWaalsContact OE1-CA 3.23Å; E79-T91 WeakPolarHBondContact OE1-CA 3.45Å; E79-T91 WeakPolarHBondContact OE1-CB 3.47Å; E79-C92 PolarHBondContact OE1-N 3.38Å; E79-C92 VanDerWaalsContact OE1-N 3.14Å
80S98.3Very high96.8Very high0 Ų046.8 Ų46.80%025%0.25CS..  trans-74.3160.317965.70000112C78 L82 Q83 M84 H148C78-S80 PolarHBondContact O-N 2.88Å; S80-L82 PolarHBondContact O-N 2.81Å; S80-Q83 PolarHBondContact O-N 2.91Å; S80-Q83 VanDerWaalsContact OG-CD 3.29Å; S80-Q83 VanDerWaalsContact OG-CG 3.28Å; S80-Q83 WeakPolarHBondContact OG-CG 3.31Å; S80-Q83 PolarHBondContact OG-N 2.88Å; S80-Q83 PolarHBondContact OG-OE1 2.73Å; S80-M84 PolarHBondContact O-N 3.01Å; S80-H148 PolarHBondContact OG-CE1 3.44Å; S80-H148 PolarHBondContact OG-NE2 3.33Å
81D97.9Very high97Very high73 Ų7344.8 Ų44.839%0.3925%0.247SC..Hα-helixtrans-58.3-40.7-179.9-68.5-10.3000111.2M84 Q85 N124D81-M84 PolarHBondContact O-N 2.81Å; D81-M84 WeakPolarHBondContact OD1-CE 3.47Å; D81-Q85 WeakPolarHBondContact O-CB 3.47Å; D81-Q85 WeakPolarHBondContact O-CG 3.32Å; D81-Q85 PolarHBondContact O-N 3.5Å; D81-Q85 PolarHBondContact O-NE2 3.35Å; D81-N124 VanDerWaalsContact CG-CG 3.48Å; D81-N124 PolarHBondContact N-ND2 2.87Å; D81-N124 PolarHBondContact N-OD1 2.96Å; D81-N124 PolarHBondContact OD1-ND2 3.27Å
82L97.6Very high97.2Very high28 Ų2844.4 Ų44.415%0.14724%0.243CC..Hα-helixtrans-65.2-39.7178-17862.9000112.5S80 Q85 T86 L133 L136S80-L82 PolarHBondContact O-N 2.81Å; L82-Q85 PolarHBondContact O-N 2.93Å; L82-T86 HydrophobicContact CD1-CG2 3.91Å; L82-T86 HydrophobicContact CG-CG2 4.46Å; L82-T86 WeakPolarHBondContact O-CB 3.42Å; L82-T86 WeakPolarHBondContact O-CG2 3.38Å; L82-T86 PolarHBondContact O-N 3.11Å; L82-T86 PolarHBondContact O-OG1 3.41Å; L82-L133 WeakPolarHBondContact CD2-O 3.33Å; L82-L136 HydrophobicContact CD2-CD1 4.05Å; L82-L136 HydrophobicContact CD2-CD2 4.09Å; L82-L136 HydrophobicContact CD2-CG 3.6Å; L82-L136 HydrophobicContact CG-CD1 3.87Å; L82-L136 HydrophobicContact CG-CG 4.01Å
83Q98.4Very high97.5Very high1 Ų147 Ų471%0.00527%0.266CS..Hα-helixtrans-66.1-43.5178.2-75165.9-49.700110.8A77 C78 E79 S80 T86 G87 V88 D90 L136 K145A77-Q83 VanDerWaalsContact O-CD 3.25Å; A77-Q83 PolarHBondContact O-NE2 2.9Å; A77-Q83 PolarHBondContact O-OE1 3.39Å; C78-Q83 VanDerWaalsContact C-OE1 3.28Å; E79-Q83 VanDerWaalsContact N-OE1 3.15Å; S80-Q83 PolarHBondContact O-N 2.91Å; S80-Q83 VanDerWaalsContact OG-CD 3.29Å; S80-Q83 VanDerWaalsContact OG-CG 3.28Å; S80-Q83 WeakPolarHBondContact OG-CG 3.31Å; S80-Q83 PolarHBondContact OG-N 2.88Å; S80-Q83 PolarHBondContact OG-OE1 2.73Å; Q83-T86 CarbonylContact O-C 3.17Å; Q83-T86 PolarHBondContact O-N 3.1Å; Q83-T86 PolarHBondContact O-OG1 3.08Å; Q83-G87 PolarHBondContact O-N 3.47Å; Q83-V88 HydrophobicContact CB-CB 4.09Å; Q83-V88 HydrophobicContact CG-CB 4.21Å; Q83-V88 HydrophobicContact CG-CG1 4.33Å; Q83-V88 PolarHBondContact O-N 2.89Å; Q83-D90 PolarHBondContact NE2-OD2 2.99Å; Q83-L136 HydrophobicContact CG-CD1 3.84Å; Q83-L136 HydrophobicContact CG-CD2 4.36Å; Q83-K145 PolarHBondContact NE2-O 3.35Å
84M97.4Very high97.9Very high123 Ų12349.6 Ų49.661%0.60628%0.278SS*.Hα-helixtrans-60.7-47.2174.1-67.9-173.7-78.200111.5S80 D81 T86 G87S80-M84 PolarHBondContact O-N 3.01Å; D81-M84 PolarHBondContact O-N 2.81Å; D81-M84 WeakPolarHBondContact OD1-CE 3.47Å; M84-T86 VanDerWaalsContact C-N 3.27Å; M84-T86 PolarHBondContact O-N 2.88Å; M84-G87 PolarHBondContact O-N 3.35Å
85Q97.2Very high98Very high150 Ų15049.5 Ų49.570%0.70128%0.277SS*.Hα-helixtrans-63.7-30.4179.3-72.8165.929.500113.4D81 L82D81-Q85 WeakPolarHBondContact O-CB 3.47Å; D81-Q85 WeakPolarHBondContact O-CG 3.32Å; D81-Q85 PolarHBondContact O-N 3.5Å; D81-Q85 PolarHBondContact O-NE2 3.35Å; L82-Q85 PolarHBondContact O-N 2.93Å
86T96.5Very high98Very high80 Ų8051.2 Ų51.249%0.49129%0.285SS..THydrogen-bonded Turntrans-99.27.1-178.957.80000113.4L82 Q83 M84 V88L82-T86 HydrophobicContact CD1-CG2 3.91Å; L82-T86 HydrophobicContact CG-CG2 4.46Å; L82-T86 WeakPolarHBondContact O-CB 3.42Å; L82-T86 WeakPolarHBondContact O-CG2 3.38Å; L82-T86 PolarHBondContact O-N 3.11Å; L82-T86 PolarHBondContact O-OG1 3.41Å; Q83-T86 CarbonylContact O-C 3.17Å; Q83-T86 PolarHBondContact O-N 3.1Å; Q83-T86 PolarHBondContact O-OG1 3.08Å; M84-T86 VanDerWaalsContact C-N 3.27Å; M84-T86 PolarHBondContact O-N 2.88Å; T86-V88 VanDerWaalsContact C-N 3.26Å; T86-V88 PolarHBondContact O-N 2.87Å
87G97.4Very high98Very high61 Ų6154.7 Ų54.763%0.62930%0.304SS*.THydrogen-bonded Turntrans71.414.8177.600000114.9Q83 M84 K89Q83-G87 PolarHBondContact O-N 3.47Å; M84-G87 PolarHBondContact O-N 3.35Å; G87-K89 PolarHBondContact O-N 2.56Å
88V97.7Very high98Very high32 Ų3255 Ų5519%0.19431%0.306CS..  trans-78.4113.5177.1-1800000109.6Q83 T86 D90 L136 V144 K145Q83-V88 HydrophobicContact CB-CB 4.09Å; Q83-V88 HydrophobicContact CG-CB 4.21Å; Q83-V88 HydrophobicContact CG-CG1 4.33Å; Q83-V88 PolarHBondContact O-N 2.89Å; T86-V88 VanDerWaalsContact C-N 3.26Å; T86-V88 PolarHBondContact O-N 2.87Å; V88-D90 HydrophobicContact CG1-CB 4.27Å; V88-D90 PolarHBondContact O-N 2.87Å; V88-D90 VanDerWaalsContact O-N 3.15Å; V88-L136 HydrophobicContact CG2-CD1 4.23Å; V88-V144 HydrophobicContact CG1-CB 4.34Å; V88-K145 HydrophobicContact CG1-CB 4.35Å; V88-K145 WeakPolarHBondContact CG1-O 3.49Å; V88-K145 HydrophobicContact CG2-CB 4.39Å
89K97.2Very high98Very high181 Ų18155.1 Ų55.179%0.78731%0.307SS*.  trans-82.686.4176.7-62.8-177.3-179-179.50110.5G87G87-K89 PolarHBondContact O-N 2.56Å
90D98.2Very high98Very high5 Ų551.2 Ų51.23%0.02729%0.289CS..  trans-121.195177.3-174.820.1000110.8E79 Q83 V88 V144 R146E79-D90 WeakPolarHBondContact CG-O 3.39Å; E79-D90 PolarHBondContact N-O 3.04Å; Q83-D90 PolarHBondContact NE2-OD2 2.99Å; V88-D90 HydrophobicContact CG1-CB 4.27Å; V88-D90 PolarHBondContact O-N 2.87Å; V88-D90 VanDerWaalsContact O-N 3.15Å; D90-V144 HydrophobicContact CB-CG2 3.59Å; D90-V144 VanDerWaalsContact CG-CG2 3.45Å; D90-V144 WeakPolarHBondContact OD1-CG2 3.35Å; D90-R146 VanDerWaalsContact CG-NE 3.32Å; D90-R146 IonicContact OD1-CZ 2.77Å; D90-R146 VanDerWaalsContact OD1-CZ 3.28Å; D90-R146 IonicContact OD1-NE 3.91Å; D90-R146 PolarHBondContact OD1-NE 2.81Å; D90-R146 IonicContact OD1-NH2 2.7Å; D90-R146 PolarHBondContact OD1-NH2 3.48Å; D90-R146 WeakPolarHBondContact OD2-CD 3.19Å; D90-R146 VanDerWaalsContact OD2-CG 3.26Å; D90-R146 WeakPolarHBondContact OD2-CG 3.27Å; D90-R146 IonicContact OD2-CZ 2.72Å; D90-R146 IonicContact OD2-NE 3.63Å; D90-R146 PolarHBondContact OD2-NE 2.97Å; D90-R146 IonicContact OD2-NH2 3.77Å
91T98.4Very high98Very high60 Ų6056.6 Ų56.637%0.36831%0.312SS..  trans-81.3157.417765.60000110.9E79 A93 L94 F95E79-T91 VanDerWaalsContact OE1-CA 3.23Å; E79-T91 WeakPolarHBondContact OE1-CA 3.45Å; E79-T91 WeakPolarHBondContact OE1-CB 3.47Å; T91-A93 PolarHBondContact O-N 3.3Å; T91-L94 WeakPolarHBondContact O-CB 3.3Å; T91-L94 PolarHBondContact O-N 3.1Å; T91-L94 PolarHBondContact OG1-N 2.99Å; T91-F95 PolarHBondContact O-N 2.73Å
92C98.5Very high98Very high15 Ų1553.2 Ų53.210%0.10129%0.294CS..Hα-helixtrans-64.8-25.6175.4-61.40000112.7C78 E79 F95 I96 A116C78-C92 HydrophobicContact CB-CB 4.11Å; C78-C92 WeakPolarHBondContact CB-SG 3.28Å; C78-C92 WeakPolarHBondContact SG-CA 3.42Å; C78-C92 WeakPolarHBondContact SG-CB 3.04Å; C78-C92 CovalentContact SG-SG 2.08Å; C78-C92 PolarHBondContact SG-SG 2.93Å; E79-C92 PolarHBondContact OE1-N 3.38Å; E79-C92 VanDerWaalsContact OE1-N 3.14Å; C92-F95 PolarHBondContact O-N 3.07Å; C92-I96 WeakPolarHBondContact O-CB 3.48Å; C92-I96 WeakPolarHBondContact O-CD1 3.2Å; C92-I96 WeakPolarHBondContact O-CG1 3.37Å; C92-I96 PolarHBondContact O-N 3Å; C92-A116 HydrophobicContact CB-CB 4.25Å
93A98.6Very high98Very high71 Ų7151.9 Ų51.959%0.58729%0.287SS*.Hα-helixtrans-62.9-42.5169.800000112.6T91 N97T91-A93 PolarHBondContact O-N 3.3Å; A93-N97 WeakPolarHBondContact O-CB 3.13Å; A93-N97 PolarHBondContact O-N 2.86Å
94L98.2Very high97.9Very high64 Ų6456 Ų5634%0.33531%0.307SS..Hα-helixtrans-64.8-42.8174.6-74.8173.9000111.4T91 N97 D98T91-L94 WeakPolarHBondContact O-CB 3.3Å; T91-L94 PolarHBondContact O-N 3.1Å; T91-L94 PolarHBondContact OG1-N 2.99Å; L94-N97 PolarHBondContact O-N 3.01Å; L94-D98 PolarHBondContact O-N 2.81Å
95F98.7Very high98Very high1 Ų156.1 Ų56.10%0.00430%0.301CS..Hα-helixtrans-64.4-42.6178-173.9-166000112.6N76 C78 T91 C92 N97 D98 T99 L115 A116 R146 L481 N484N76-F95 HydrophobicContact CB-CE1 4.2Å; N76-F95 HydrophobicContact CB-CE2 4.22Å; N76-F95 HydrophobicContact CB-CZ 3.61Å; C78-F95 HydrophobicContact CB-CB 3.99Å; C78-F95 HydrophobicContact CB-CD1 3.99Å; C78-F95 HydrophobicContact CB-CG 4.46Å; T91-F95 PolarHBondContact O-N 2.73Å; C92-F95 PolarHBondContact O-N 3.07Å; F95-N97 VanDerWaalsContact C-N 3.33Å; F95-N97 PolarHBondContact O-N 3.08Å; F95-D98 PolarHBondContact O-N 3.19Å; F95-T99 WeakPolarHBondContact CE2-OG1 3.23Å; F95-T99 WeakPolarHBondContact O-CB 3.25Å; F95-T99 PolarHBondContact O-N 3Å; F95-T99 PolarHBondContact O-OG1 3.13Å; F95-L115 HydrophobicContact CE1-CD2 3.77Å; F95-L115 HydrophobicContact CE2-CD2 4.41Å; F95-L115 HydrophobicContact CZ-CD2 3.53Å; F95-A116 HydrophobicContact CB-CB 4.46Å; F95-A116 HydrophobicContact CD1-CB 3.76Å; F95-A116 HydrophobicContact CE1-CB 4.33Å; F95-A116 HydrophobicContact CG-CB 4.28Å; F95-R146 VanDerWaalsContact CE2-CD 3.48Å; F95-R146 VanDerWaalsContact CG-CD 3.43Å; F95-L481 HydrophobicContact CD2-CD2 4.38Å; F95-L481 HydrophobicContact CE2-CD2 4.14Å; F95-N484 WeakPolarHBondContact CE2-OD1 3.24Å; F95-N484 VanDerWaalsContact CZ-OD1 3.22Å; F95-N484 WeakPolarHBondContact CZ-OD1 3.34Å
96I98.8Very high98Very high35 Ų3552.5 Ų52.518%0.17929%0.285CS..Hα-helixtrans-58.8-47.9173-70162.4000109.6C92 D98 T99 L100 V112 K113 A116C92-I96 WeakPolarHBondContact O-CB 3.48Å; C92-I96 WeakPolarHBondContact O-CD1 3.2Å; C92-I96 WeakPolarHBondContact O-CG1 3.37Å; C92-I96 PolarHBondContact O-N 3Å; I96-D98 PolarHBondContact O-N 3.48Å; I96-T99 PolarHBondContact O-N 3.02Å; I96-L100 HydrophobicContact CG2-CD1 3.81Å; I96-L100 HydrophobicContact CG2-CG 4.16Å; I96-L100 WeakPolarHBondContact O-CB 3.48Å; I96-L100 VanDerWaalsContact O-CG 3.28Å; I96-L100 WeakPolarHBondContact O-CG 3.24Å; I96-L100 PolarHBondContact O-N 2.66Å; I96-V112 HydrophobicContact CB-CG1 4.23Å; I96-V112 HydrophobicContact CG1-CG1 4.17Å; I96-V112 HydrophobicContact CG2-CG1 4.01Å; I96-K113 HydrophobicContact CD1-CB 4.19Å; I96-K113 HydrophobicContact CD1-CG 4.16Å; I96-A116 HydrophobicContact CD1-CB 4.26Å; I96-A116 HydrophobicContact CG1-CB 3.69Å
97N98.6Very high98.1Very high73 Ų7349.1 Ų49.139%0.3926%0.264SS..Hα-helixtrans-61.2-46.7-179.3-178.470.3000112.8A93 L94 F95 T99 L100 K101A93-N97 WeakPolarHBondContact O-CB 3.13Å; A93-N97 PolarHBondContact O-N 2.86Å; L94-N97 PolarHBondContact O-N 3.01Å; F95-N97 VanDerWaalsContact C-N 3.33Å; F95-N97 PolarHBondContact O-N 3.08Å; N97-T99 VanDerWaalsContact C-N 3.29Å; N97-T99 PolarHBondContact O-N 2.9Å; N97-L100 PolarHBondContact O-N 3.06Å; N97-K101 WeakPolarHBondContact O-CB 3.31Å; N97-K101 PolarHBondContact O-N 3.15Å
98D98.4Very high98.1Very high8 Ų849.3 Ų49.34%0.04325%0.251CS..Hα-helixtrans-59.4-42.2176.4-71.2-6.3000111.2L94 F95 I96 K101 A102 S143 R146 L481L94-D98 PolarHBondContact O-N 2.81Å; F95-D98 PolarHBondContact O-N 3.19Å; I96-D98 PolarHBondContact O-N 3.48Å; D98-K101 PolarHBondContact O-N 2.86Å; D98-A102 WeakPolarHBondContact O-CB 3.22Å; D98-A102 PolarHBondContact O-N 3Å; D98-S143 WeakPolarHBondContact OD1-CB 3.49Å; D98-S143 PolarHBondContact OD1-OG 2.82Å; D98-S143 PolarHBondContact OD2-N 2.87Å; D98-S143 PolarHBondContact OD2-OG 3.47Å; D98-R146 IonicContact OD2-CZ 2.8Å; D98-R146 VanDerWaalsContact OD2-CZ 3.31Å; D98-R146 IonicContact OD2-NH1 3.16Å; D98-R146 PolarHBondContact OD2-NH1 3.19Å; D98-R146 IonicContact OD2-NH2 3.6Å; D98-R146 PolarHBondContact OD2-NH2 3.01Å; D98-L481 HydrophobicContact CB-CD2 3.83Å
99T98.5Very high98.1Very high2 Ų255.4 Ų55.41%0.01227%0.27CS..Hα-helixtrans-67.1-43.2179.7-59.50000111.7F95 I96 N97 A102 G103 N107 V112 N484F95-T99 WeakPolarHBondContact CE2-OG1 3.23Å; F95-T99 WeakPolarHBondContact O-CB 3.25Å; F95-T99 PolarHBondContact O-N 3Å; F95-T99 PolarHBondContact O-OG1 3.13Å; I96-T99 PolarHBondContact O-N 3.02Å; N97-T99 VanDerWaalsContact C-N 3.29Å; N97-T99 PolarHBondContact O-N 2.9Å; T99-A102 PolarHBondContact O-N 2.97Å; T99-G103 PolarHBondContact O-N 2.96Å; T99-N107 PolarHBondContact O-ND2 2.82Å; T99-V112 HydrophobicContact CG2-CB 4.5Å; T99-V112 HydrophobicContact CG2-CG1 3.71Å; T99-V112 HydrophobicContact CG2-CG2 3.98Å; T99-N484 WeakPolarHBondContact CG2-ND2 3.35Å; T99-N484 PolarHBondContact OG1-ND2 3.04Å
100L98.5Very high98.2Very high12 Ų1252 Ų526%0.06326%0.26CS..Hα-helixtrans-64.6-41.7175.5-68.5178.7000111.6I96 N97 G103 Q104 Y105 N107 R109 V112I96-L100 HydrophobicContact CG2-CD1 3.81Å; I96-L100 HydrophobicContact CG2-CG 4.16Å; I96-L100 WeakPolarHBondContact O-CB 3.48Å; I96-L100 VanDerWaalsContact O-CG 3.28Å; I96-L100 WeakPolarHBondContact O-CG 3.24Å; I96-L100 PolarHBondContact O-N 2.66Å; N97-L100 PolarHBondContact O-N 3.06Å; L100-G103 CarbonylContact O-C 3.3Å; L100-G103 PolarHBondContact O-N 2.99Å; L100-Q104 PolarHBondContact O-N 2.85Å; L100-Q104 VanDerWaalsContact O-N 3.14Å; L100-Y105 HydrophobicContact CB-CD1 3.75Å; L100-Y105 HydrophobicContact CB-CE1 3.89Å; L100-Y105 PolarHBondContact O-N 3.04Å; L100-N107 HydrophobicContact CD2-CB 3.73Å; L100-R109 HydrophobicContact CD1-CG 4.35Å; L100-R109 HydrophobicContact CD2-CG 3.97Å; L100-V112 HydrophobicContact CD2-CB 4.47Å; L100-V112 HydrophobicContact CD2-CG1 4.47Å; L100-V112 HydrophobicContact CD2-CG2 4.09Å
101K98Very high98.2Very high114 Ų11452.1 Ų52.150%0.49626%0.261SS..Hα-helixtrans-64.5-42.2178.5-166-171.1175178.20111.4N97 D98 G103 Q104 Q327N97-K101 WeakPolarHBondContact O-CB 3.31Å; N97-K101 PolarHBondContact O-N 3.15Å; D98-K101 PolarHBondContact O-N 2.86Å; K101-G103 VanDerWaalsContact C-N 3.34Å; K101-Q104 PolarHBondContact O-N 3.02Å; K101-Q327 VanDerWaalsContact C-NE2 3.32Å; K101-Q327 PolarHBondContact O-NE2 2.94Å
102A97.2Very high98.2Very high2 Ų249.3 Ų49.32%0.01724%0.243CC..Hα-helixtrans-63.5-40.6173.900000111.5D98 T99 Q104 D479 L481D98-A102 WeakPolarHBondContact O-CB 3.22Å; D98-A102 PolarHBondContact O-N 3Å; T99-A102 PolarHBondContact O-N 2.97Å; A102-Q104 PolarHBondContact O-N 3.44Å; A102-Q104 VanDerWaalsContact O-N 3.17Å; A102-D479 CarbonylContact C-O 3.59Å; A102-D479 WeakPolarHBondContact O-CB 3.48Å; A102-L481 HydrophobicContact CB-CB 4.04Å; A102-L481 HydrophobicContact CB-CD1 4.18Å
103G97.7Very high98.2Very high0 Ų053.3 Ų53.30%026%0.259CS..THydrogen-bonded Turntrans-77.29.1176.400000115.5T99 L100 K101 Y105 M106 N107 H476 Y478 D479T99-G103 PolarHBondContact O-N 2.96Å; L100-G103 CarbonylContact O-C 3.3Å; L100-G103 PolarHBondContact O-N 2.99Å; K101-G103 VanDerWaalsContact C-N 3.34Å; G103-Y105 PolarHBondContact O-N 3.49Å; G103-Y105 VanDerWaalsContact O-N 3.08Å; G103-M106 WeakPolarHBondContact O-CB 3.26Å; G103-M106 PolarHBondContact O-N 3.02Å; G103-N107 VanDerWaalsContact CA-OD1 3.31Å; G103-N107 WeakPolarHBondContact CA-OD1 3.31Å; G103-H476 WeakPolarHBondContact CA-O 3.11Å; G103-Y478 WeakPolarHBondContact O-CB 3.5Å; G103-Y478 PolarHBondContact O-N 3.43Å; G103-D479 WeakPolarHBondContact CA-O 3.44Å; G103-D479 PolarHBondContact N-O 3.42Å
104Q97.3Very high98.2Very high88 Ų8851.7 Ų51.741%0.41124%0.24SC..THydrogen-bonded Turntrans4735.5-172.8-57.3-172.37.200113.1L100 K101 A102 M106 D329 Y478L100-Q104 PolarHBondContact O-N 2.85Å; L100-Q104 VanDerWaalsContact O-N 3.14Å; K101-Q104 PolarHBondContact O-N 3.02Å; A102-Q104 PolarHBondContact O-N 3.44Å; A102-Q104 VanDerWaalsContact O-N 3.17Å; Q104-M106 PolarHBondContact O-N 3.3Å; Q104-D329 PolarHBondContact NE2-OD2 3.38Å; Q104-D329 VanDerWaalsContact NE2-OD2 3.1Å; Q104-Y478 HydrophobicContact CB-CG 4.23Å; Q104-Y478 VanDerWaalsContact CD-CD1 3.45Å; Q104-Y478 VanDerWaalsContact CD-CG 3.49Å; Q104-Y478 HydrophobicContact CG-CD1 3.87Å; Q104-Y478 HydrophobicContact CG-CG 3.84Å
105Y97.9Very high98.2Very high124 Ų12448.9 Ų48.949%0.48623%0.225SC..THydrogen-bonded Turntrans60.111.7-178.2-52.4-84.9000115.4L100 G103 N107L100-Y105 HydrophobicContact CB-CD1 3.75Å; L100-Y105 HydrophobicContact CB-CE1 3.89Å; L100-Y105 PolarHBondContact O-N 3.04Å; G103-Y105 PolarHBondContact O-N 3.49Å; G103-Y105 VanDerWaalsContact O-N 3.08Å; Y105-N107 PolarHBondContact O-N 2.79Å
106M97.9Very high98.2Very high74 Ų7448.9 Ų48.937%0.36523%0.226SC..  trans-73-14.9172.1-68.2-179.155.600112.5G103 Q104 D277 Y478G103-M106 WeakPolarHBondContact O-CB 3.26Å; G103-M106 PolarHBondContact O-N 3.02Å; Q104-M106 PolarHBondContact O-N 3.3Å; M106-D277 WeakPolarHBondContact CE-OD1 3.34Å; M106-Y478 HydrophobicContact SD-CD2 3.99Å; M106-Y478 HydrophobicContact SD-CG 4.44Å
107N98.3Very high98.2Very high9 Ų952.4 Ų52.45%0.04824%0.242CC..SBendtrans-59.8148.1-177.6-4064000112.1T99 L100 G103 Y105 R109 V112 G474 T475 H476T99-N107 PolarHBondContact O-ND2 2.82Å; L100-N107 HydrophobicContact CD2-CB 3.73Å; G103-N107 VanDerWaalsContact CA-OD1 3.31Å; G103-N107 WeakPolarHBondContact CA-OD1 3.31Å; Y105-N107 PolarHBondContact O-N 2.79Å; N107-R109 PolarHBondContact O-N 2.77Å; N107-R109 VanDerWaalsContact O-N 3.13Å; N107-V112 HydrophobicContact CB-CG2 3.57Å; N107-G474 CarbonylContact C-O 3.54Å; N107-G474 WeakPolarHBondContact CA-O 3.35Å; N107-T475 PolarHBondContact ND2-O 3.36Å; N107-H476 WeakPolarHBondContact ND2-CA 3.37Å; N107-H476 PolarHBondContact ND2-O 2.95Å
108N98.2Very high98.2Very high65 Ų6552.2 Ų52.235%0.34824%0.235SC..  trans-69107.2158.3-175.4-31.3000109.6L110 L111 V112 G474N108-L110 PolarHBondContact O-N 2.81Å; N108-L110 WeakPolarHBondContact OD1-CB 3.08Å; N108-L110 PolarHBondContact OD1-N 2.88Å; N108-L111 HydrophobicContact CB-CB 4.28Å; N108-L111 HydrophobicContact CB-CD1 3.99Å; N108-L111 HydrophobicContact CB-CG 4.04Å; N108-L111 PolarHBondContact O-N 2.95Å; N108-L111 VanDerWaalsContact O-N 3.08Å; N108-L111 PolarHBondContact OD1-N 2.75Å; N108-V112 PolarHBondContact O-N 2.83Å; N108-V112 VanDerWaalsContact O-N 3.1Å; N108-G474 PolarHBondContact N-O 3.09Å
109R98.3Very high98.2Very high161 Ų16151.8 Ų51.861%0.60823%0.233SC*.Hα-helixtrans-57.4-31.2-177.7-66.3-176173.4-148.9-1.3113.8L100 N107 K113L100-R109 HydrophobicContact CD1-CG 4.35Å; L100-R109 HydrophobicContact CD2-CG 3.97Å; N107-R109 PolarHBondContact O-N 2.77Å; N107-R109 VanDerWaalsContact O-N 3.13Å; R109-K113 VanDerWaalsContact O-CB 3.32Å; R109-K113 WeakPolarHBondContact O-CB 3.31Å; R109-K113 PolarHBondContact O-N 3.35Å
110L98.3Very high98.2Very high109 Ų10952.6 Ų52.657%0.57124%0.24SC*.Hα-helixtrans-70.2-39.4178.3-63.4176.3000111.4N108 K113 L114 T450N108-L110 PolarHBondContact O-N 2.81Å; N108-L110 WeakPolarHBondContact OD1-CB 3.08Å; N108-L110 PolarHBondContact OD1-N 2.88Å; L110-K113 PolarHBondContact O-N 2.75Å; L110-L114 WeakPolarHBondContact O-CB 3.49Å; L110-L114 PolarHBondContact O-N 3.38Å; L110-T450 HydrophobicContact CB-CG2 3.72Å; L110-T450 HydrophobicContact CD1-CG2 4.44Å
111L98.6Very high98.1Very high8 Ų855.8 Ų55.84%0.04226%0.263CS..Hα-helixtrans-68.3-40175.7-62.4-178.2000111.5N108 L114 L115 T450 M452N108-L111 HydrophobicContact CB-CB 4.28Å; N108-L111 HydrophobicContact CB-CD1 3.99Å; N108-L111 HydrophobicContact CB-CG 4.04Å; N108-L111 PolarHBondContact O-N 2.95Å; N108-L111 VanDerWaalsContact O-N 3.08Å; N108-L111 PolarHBondContact OD1-N 2.75Å; L111-L114 PolarHBondContact O-N 2.86Å; L111-L115 WeakPolarHBondContact O-CB 3.36Å; L111-L115 PolarHBondContact O-N 3.4Å; L111-T450 HydrophobicContact CD2-CG2 4.37Å; L111-M452 HydrophobicContact CD2-CE 3.83Å
112V98.7Very high98.1Very high1 Ų151.4 Ų51.41%0.00624%0.244CC..Hα-helixtrans-62.7-44.5174.9177.80000111.3I96 T99 L100 N107 N108 L115 A116 T475I96-V112 HydrophobicContact CB-CG1 4.23Å; I96-V112 HydrophobicContact CG1-CG1 4.17Å; I96-V112 HydrophobicContact CG2-CG1 4.01Å; T99-V112 HydrophobicContact CG2-CB 4.5Å; T99-V112 HydrophobicContact CG2-CG1 3.71Å; T99-V112 HydrophobicContact CG2-CG2 3.98Å; L100-V112 HydrophobicContact CD2-CB 4.47Å; L100-V112 HydrophobicContact CD2-CG1 4.47Å; L100-V112 HydrophobicContact CD2-CG2 4.09Å; N107-V112 HydrophobicContact CB-CG2 3.57Å; N108-V112 PolarHBondContact O-N 2.83Å; N108-V112 VanDerWaalsContact O-N 3.1Å; V112-L115 PolarHBondContact O-N 3.16Å; V112-A116 PolarHBondContact O-N 2.82Å; V112-T475 WeakPolarHBondContact CG2-O 3.35Å
113K98.6Very high98.2Very high99 Ų9951.4 Ų51.443%0.4324%0.244SC..Hα-helixtrans-59.7-49.1176.2-178.6178177.8-177.20111.1I96 R109 L110 L115 A116 E117I96-K113 HydrophobicContact CD1-CB 4.19Å; I96-K113 HydrophobicContact CD1-CG 4.16Å; R109-K113 VanDerWaalsContact O-CB 3.32Å; R109-K113 WeakPolarHBondContact O-CB 3.31Å; R109-K113 PolarHBondContact O-N 3.35Å; L110-K113 PolarHBondContact O-N 2.75Å; K113-L115 VanDerWaalsContact C-N 3.3Å; K113-L115 PolarHBondContact O-N 3.29Å; K113-A116 PolarHBondContact O-N 2.94Å; K113-E117 WeakPolarHBondContact CE-OE1 3.21Å; K113-E117 WeakPolarHBondContact CE-OE2 3.1Å; K113-E117 HydrophobicContact CG-CG 4.22Å; K113-E117 IonicContact NZ-OE1 3.61Å; K113-E117 WeakPolarHBondContact O-CB 2.94Å; K113-E117 WeakPolarHBondContact O-CG 3.48Å; K113-E117 PolarHBondContact O-N 3.26Å
114L97.9Very high98.2Very high36 Ų3653.2 Ų53.219%0.18825%0.254CS..Hα-helixtrans-58.2-41.4177.9-176.168000112.3L110 L111 R118 T450 M452 L495L110-L114 WeakPolarHBondContact O-CB 3.49Å; L110-L114 PolarHBondContact O-N 3.38Å; L111-L114 PolarHBondContact O-N 2.86Å; L114-R118 VanDerWaalsContact CD1-CD 3.47Å; L114-R118 HydrophobicContact CD1-CG 4.33Å; L114-R118 WeakPolarHBondContact O-CB 3.39Å; L114-R118 WeakPolarHBondContact O-CD 3.41Å; L114-R118 VanDerWaalsContact O-CG 3.3Å; L114-R118 WeakPolarHBondContact O-CG 3.32Å; L114-R118 PolarHBondContact O-N 3.13Å; L114-T450 WeakPolarHBondContact CD2-O 3.12Å; L114-M452 HydrophobicContact CD2-CE 3.86Å; L114-L495 HydrophobicContact CD2-CD2 3.85Å
115L98.4Very high98.2Very high5 Ų552.5 Ų52.53%0.02625%0.25CS..Hα-helixtrans-62.7-48.2176-179.6152.8000111.5F95 L111 V112 K113 S119 T475 I487 E488F95-L115 HydrophobicContact CE1-CD2 3.77Å; F95-L115 HydrophobicContact CE2-CD2 4.41Å; F95-L115 HydrophobicContact CZ-CD2 3.53Å; L111-L115 WeakPolarHBondContact O-CB 3.36Å; L111-L115 PolarHBondContact O-N 3.4Å; V112-L115 PolarHBondContact O-N 3.16Å; K113-L115 VanDerWaalsContact C-N 3.3Å; K113-L115 PolarHBondContact O-N 3.29Å; L115-S119 WeakPolarHBondContact O-CB 3.3Å; L115-S119 PolarHBondContact O-N 3.48Å; L115-T475 HydrophobicContact CD1-CG2 3.81Å; L115-I487 HydrophobicContact CD1-CG2 4.27Å; L115-I487 HydrophobicContact CD2-CG2 3.86Å; L115-I487 HydrophobicContact CG-CG2 4.08Å; L115-E488 HydrophobicContact CD1-CB 3.77Å; L115-E488 HydrophobicContact CD1-CG 4.48Å
116A98.7Very high98.1Very high1 Ų146.6 Ų46.61%0.00823%0.227CC..Hα-helixtrans-64.9-52.8-178.600000111.4C78 C92 F95 I96 V112 K113 R118 S119C78-A116 PolarHBondContact SG-O 3.22Å; C92-A116 HydrophobicContact CB-CB 4.25Å; F95-A116 HydrophobicContact CB-CB 4.46Å; F95-A116 HydrophobicContact CD1-CB 3.76Å; F95-A116 HydrophobicContact CE1-CB 4.33Å; F95-A116 HydrophobicContact CG-CB 4.28Å; I96-A116 HydrophobicContact CD1-CB 4.26Å; I96-A116 HydrophobicContact CG1-CB 3.69Å; V112-A116 PolarHBondContact O-N 2.82Å; K113-A116 PolarHBondContact O-N 2.94Å; A116-R118 VanDerWaalsContact C-N 3.25Å; A116-R118 PolarHBondContact O-N 2.84Å; A116-S119 VanDerWaalsContact O-CB 3.3Å; A116-S119 WeakPolarHBondContact O-CB 3.42Å; A116-S119 PolarHBondContact O-N 3.46Å; A116-S119 PolarHBondContact O-OG 3.02Å
117E98.3Very high97.9Very high110 Ų11046.4 Ų46.451%0.51423%0.231SC..Hα-helixtrans-63.8-28.3-174.8-69.9179.5156.200113.4K113K113-E117 WeakPolarHBondContact CE-OE1 3.21Å; K113-E117 WeakPolarHBondContact CE-OE2 3.1Å; K113-E117 HydrophobicContact CG-CG 4.22Å; K113-E117 IonicContact NZ-OE1 3.61Å; K113-E117 WeakPolarHBondContact O-CB 2.94Å; K113-E117 WeakPolarHBondContact O-CG 3.48Å; K113-E117 PolarHBondContact O-N 3.26Å
118R98.1Very high97.7Very high68 Ų6854.4 Ų54.426%0.25727%0.266SS..Hα-helixtrans-86.6-12.4177.6-6717263.486.5-4.5113.4L114 A116 A120 S121 F122 S491L114-R118 VanDerWaalsContact CD1-CD 3.47Å; L114-R118 HydrophobicContact CD1-CG 4.33Å; L114-R118 WeakPolarHBondContact O-CB 3.39Å; L114-R118 WeakPolarHBondContact O-CD 3.41Å; L114-R118 VanDerWaalsContact O-CG 3.3Å; L114-R118 WeakPolarHBondContact O-CG 3.32Å; L114-R118 PolarHBondContact O-N 3.13Å; A116-R118 VanDerWaalsContact C-N 3.25Å; A116-R118 PolarHBondContact O-N 2.84Å; R118-A120 PolarHBondContact O-N 2.98Å; R118-S121 PolarHBondContact O-N 3.09Å; R118-F122 HydrophobicContact CB-CD2 4.27Å; R118-F122 HydrophobicContact CB-CE2 3.98Å; R118-F122 VanDerWaalsContact O-CD2 3.22Å; R118-F122 WeakPolarHBondContact O-CD2 3.39Å; R118-S491 VanDerWaalsContact CD-OG 3.26Å; R118-S491 WeakPolarHBondContact CD-OG 3.22Å; R118-S491 PolarHBondContact NE-OG 2.96Å
119S98.6Very high97.5Very high0 Ų054.5 Ų54.50%026%0.261CS..Hα-helixtrans-65.2-44.8-166.966.70000114A77 C78 L115 A116 S121 F122 V123A77-S119 VanDerWaalsContact CA-OG 3.31Å; A77-S119 WeakPolarHBondContact CA-OG 3.38Å; C78-S119 PolarHBondContact N-OG 3.36Å; C78-S119 VanDerWaalsContact N-OG 3.11Å; C78-S119 PolarHBondContact SG-OG 3Å; L115-S119 WeakPolarHBondContact O-CB 3.3Å; L115-S119 PolarHBondContact O-N 3.48Å; A116-S119 VanDerWaalsContact O-CB 3.3Å; A116-S119 WeakPolarHBondContact O-CB 3.42Å; A116-S119 PolarHBondContact O-N 3.46Å; A116-S119 PolarHBondContact O-OG 3.02Å; S119-S121 PolarHBondContact O-N 3.49Å; S119-F122 PolarHBondContact O-N 2.8Å; S119-V123 PolarHBondContact O-N 3.39Å
120A98.4Very high97.2Very high19 Ų1949.1 Ų49.116%0.15726%0.256CS..Hα-helixtrans-58.6-46.5179.500000112C78 R118 F122 V123 N124C78-A120 WeakPolarHBondContact O-CB 3.4Å; R118-A120 PolarHBondContact O-N 2.98Å; A120-F122 VanDerWaalsContact C-N 3.33Å; A120-F122 PolarHBondContact O-N 3.23Å; A120-V123 PolarHBondContact O-N 3.01Å; A120-N124 WeakPolarHBondContact O-CB 3.4Å; A120-N124 PolarHBondContact O-N 3.26Å; A120-N124 PolarHBondContact O-ND2 3.28Å
121S97.7Very high96.9Very high79 Ų7944.4 Ų44.455%0.55223%0.232SC*.Hα-helixtrans-56.4-47.1-178.31680000111.6R118 S119 E125R118-S121 PolarHBondContact O-N 3.09Å; S119-S121 PolarHBondContact O-N 3.49Å; S121-E125 PolarHBondContact O-N 2.96Å
122F97.7Very high96.7Very high21 Ų2148.2 Ų48.29%0.09225%0.252CS..Hα-helixtrans-69.9-44.8179.5-70.5-61.1000112.3R118 S119 A120 N124 E125 L126 I487 I490R118-F122 HydrophobicContact CB-CD2 4.27Å; R118-F122 HydrophobicContact CB-CE2 3.98Å; R118-F122 VanDerWaalsContact O-CD2 3.22Å; R118-F122 WeakPolarHBondContact O-CD2 3.39Å; S119-F122 PolarHBondContact O-N 2.8Å; A120-F122 VanDerWaalsContact C-N 3.33Å; A120-F122 PolarHBondContact O-N 3.23Å; F122-N124 PolarHBondContact O-N 3.08Å; F122-E125 PolarHBondContact O-N 3.46Å; F122-L126 WeakPolarHBondContact O-CG 3.33Å; F122-L126 PolarHBondContact O-N 2.96Å; F122-I487 HydrophobicContact CB-CD1 4.02Å; F122-I487 HydrophobicContact CD2-CD1 4.15Å; F122-I490 HydrophobicContact CB-CG2 3.94Å; F122-I490 HydrophobicContact CD1-CG2 3.44Å; F122-I490 VanDerWaalsContact CD1-CG2 3.44Å; F122-I490 HydrophobicContact CD2-CG2 3.84Å; F122-I490 HydrophobicContact CE1-CG2 3.78Å; F122-I490 HydrophobicContact CE2-CG2 4.16Å; F122-I490 HydrophobicContact CG-CG2 3.46Å; F122-I490 VanDerWaalsContact CG-CG2 3.46Å; F122-I490 HydrophobicContact CZ-CG2 4.13Å
123V98.3Very high96.5Very high3 Ų348.6 Ų48.62%0.01825%0.254CS..Hα-helixtrans-65.9-39.6-178.5170.20000111.9I75 A77 S119 A120 E125 L126 P127 L133 H148I75-V123 HydrophobicContact CD1-CG2 4.12Å; I75-V123 HydrophobicContact CG1-CG2 4.23Å; I75-V123 HydrophobicContact CG2-CG2 4.18Å; A77-V123 HydrophobicContact CB-CB 3.82Å; A77-V123 HydrophobicContact CB-CG1 4.24Å; A77-V123 HydrophobicContact CB-CG2 3.63Å; S119-V123 PolarHBondContact O-N 3.39Å; A120-V123 PolarHBondContact O-N 3.01Å; V123-E125 VanDerWaalsContact C-N 3.27Å; V123-E125 PolarHBondContact O-N 2.87Å; V123-L126 PolarHBondContact O-N 2.71Å; V123-P127 VanDerWaalsContact O-CD 3.25Å; V123-P127 WeakPolarHBondContact O-CD 3.31Å; V123-L133 HydrophobicContact CG1-CD1 4.16Å; V123-H148 HydrophobicContact CG1-CB 4.38Å
124N98Very high96.3Very high38 Ų3846.9 Ų46.920%0.20326%0.255CS..Hα-helixtrans-71.3-19.9178.9-69.9-10.3000113D81 A120 F122D81-N124 VanDerWaalsContact CG-CG 3.48Å; D81-N124 PolarHBondContact N-ND2 2.87Å; D81-N124 PolarHBondContact N-OD1 2.96Å; D81-N124 PolarHBondContact OD1-ND2 3.27Å; A120-N124 WeakPolarHBondContact O-CB 3.4Å; A120-N124 PolarHBondContact O-N 3.26Å; A120-N124 PolarHBondContact O-ND2 3.28Å; F122-N124 PolarHBondContact O-N 3.08Å
125E96.6Very high96.1Very high72 Ų7246.6 Ų46.634%0.33625%0.252SS..Hα-helixtrans-79.5-34.6177.2-159.7-171.815400112.5S121 F122 V123 K128 W129S121-E125 PolarHBondContact O-N 2.96Å; F122-E125 PolarHBondContact O-N 3.46Å; V123-E125 VanDerWaalsContact C-N 3.27Å; V123-E125 PolarHBondContact O-N 2.87Å; E125-K128 HydrophobicContact CG-CD 4.48Å; E125-K128 VanDerWaalsContact O-CB 3.26Å; E125-K128 WeakPolarHBondContact O-CB 3.37Å; E125-K128 PolarHBondContact O-N 3.5Å; E125-W129 PolarHBondContact OE1-NE1 2.97Å
126L96.1Very high96Very high1 Ų147.5 Ų47.51%0.00526%0.257CS..G310 helixtrans-55.6-37-173.8-73.3167.8000115.1F122 V123 K128 W129 G130 L131 L133 L165 Y169 M172F122-L126 WeakPolarHBondContact O-CG 3.33Å; F122-L126 PolarHBondContact O-N 2.96Å; V123-L126 PolarHBondContact O-N 2.71Å; L126-K128 VanDerWaalsContact C-N 3.3Å; L126-K128 PolarHBondContact O-N 3.43Å; L126-W129 CarbonylContact O-C 3.57Å; L126-W129 WeakPolarHBondContact O-CA 3.42Å; L126-W129 WeakPolarHBondContact O-CB 3.43Å; L126-W129 PolarHBondContact O-N 2.91Å; L126-W129 VanDerWaalsContact O-N 3.12Å; L126-G130 PolarHBondContact O-N 2.91Å; L126-L131 HydrophobicContact CB-CB 4.18Å; L126-L131 HydrophobicContact CB-CD2 4.2Å; L126-L131 HydrophobicContact CD1-CD2 4.19Å; L126-L131 HydrophobicContact CD2-CD2 4.07Å; L126-L131 HydrophobicContact CG-CD2 4.39Å; L126-L131 WeakPolarHBondContact O-CB 3.45Å; L126-L131 PolarHBondContact O-N 2.93Å; L126-L133 HydrophobicContact CB-CD1 3.97Å; L126-L133 HydrophobicContact CD1-CD1 3.62Å; L126-L133 HydrophobicContact CG-CD1 4.46Å; L126-L165 HydrophobicContact CD1-CD2 3.47Å; L126-L165 VanDerWaalsContact CD1-CD2 3.47Å; L126-L165 HydrophobicContact CD2-CD2 3.85Å; L126-L165 HydrophobicContact CG-CD2 4.33Å; L126-Y169 HydrophobicContact CD2-CE2 3.8Å; L126-M172 HydrophobicContact CD2-CE 4.48Å
127P95.1Very high95.8Very high69 Ų6947.6 Ų47.645%0.44826%0.258SS..G310 helixtrans-60-33.8171.7-28.136.6000114.5V123 W129 G130 L131V123-P127 VanDerWaalsContact O-CD 3.25Å; V123-P127 WeakPolarHBondContact O-CD 3.31Å; P127-W129 PolarHBondContact O-N 2.94Å; P127-G130 WeakPolarHBondContact O-CA 3.41Å; P127-G130 PolarHBondContact O-N 2.93Å; P127-L131 WeakPolarHBondContact CA-O 3.2Å
128K93.4Very high95.7Very high178 Ų17843.2 Ų43.277%0.77424%0.237SC*.G310 helixtrans-65.4-28.6176.5-55.4178.6-175.5173.10111.5E125 L126 G130E125-K128 HydrophobicContact CG-CD 4.48Å; E125-K128 VanDerWaalsContact O-CB 3.26Å; E125-K128 WeakPolarHBondContact O-CB 3.37Å; E125-K128 PolarHBondContact O-N 3.5Å; L126-K128 VanDerWaalsContact C-N 3.3Å; L126-K128 PolarHBondContact O-N 3.43Å; K128-G130 VanDerWaalsContact C-N 3.27Å
129W93.5Very high95.7Very high66 Ų6640 Ų4025%0.2523%0.225CC..G310 helixtrans-86.54.3173.1-68.398000112.5E125 L126 P127 R168 M172 L175E125-W129 PolarHBondContact OE1-NE1 2.97Å; L126-W129 CarbonylContact O-C 3.57Å; L126-W129 WeakPolarHBondContact O-CA 3.42Å; L126-W129 WeakPolarHBondContact O-CB 3.43Å; L126-W129 PolarHBondContact O-N 2.91Å; L126-W129 VanDerWaalsContact O-N 3.12Å; P127-W129 PolarHBondContact O-N 2.94Å; W129-R168 HydrophobicContact CB-CG 3.71Å; W129-R168 WeakPolarHBondContact O-CD 3.41Å; W129-R168 PolarHBondContact O-NE 2.86Å; W129-R168 PolarHBondContact O-NH1 2.93Å; W129-R168 PolarHBondContact O-NH2 3.27Å; W129-M172 HydrophobicContact CB-CE 3.75Å; W129-M172 HydrophobicContact CD2-CE 3.45Å; W129-M172 VanDerWaalsContact CD2-CE 3.45Å; W129-M172 HydrophobicContact CD2-CG 3.86Å; W129-M172 HydrophobicContact CD2-SD 4.29Å; W129-M172 HydrophobicContact CE3-CE 4.21Å; W129-M172 HydrophobicContact CE3-CG 3.83Å; W129-M172 HydrophobicContact CG-CE 3.19Å; W129-M172 HydrophobicContact CH2-CB 4.43Å; W129-M172 HydrophobicContact CH2-CG 3.8Å; W129-M172 HydrophobicContact CZ2-CG 3.82Å; W129-M172 HydrophobicContact CZ2-SD 4.41Å; W129-M172 HydrophobicContact CZ3-CG 3.81Å; W129-L175 HydrophobicContact CH2-CD1 4.08Å; W129-L175 HydrophobicContact CZ3-CD1 3.58Å
130G92.1Very high95.6Very high49 Ų4940.1 Ų40.151%0.50523%0.227SC..THydrogen-bonded Turntrans84.817.217600000114.3L126 P127 K128 R168L126-G130 PolarHBondContact O-N 2.91Å; P127-G130 WeakPolarHBondContact O-CA 3.41Å; P127-G130 PolarHBondContact O-N 2.93Å; K128-G130 VanDerWaalsContact C-N 3.27Å; G130-R168 PolarHBondContact O-NH2 2.84Å
131L93.2Very high95.4Very high10 Ų1040.2 Ų40.25%0.05223%0.229CC..  trans-95.2105.4170.7-170.268.7000109.7L126 P127 L133 I150 A164 L165L126-L131 HydrophobicContact CB-CB 4.18Å; L126-L131 HydrophobicContact CB-CD2 4.2Å; L126-L131 HydrophobicContact CD1-CD2 4.19Å; L126-L131 HydrophobicContact CD2-CD2 4.07Å; L126-L131 HydrophobicContact CG-CD2 4.39Å; L126-L131 WeakPolarHBondContact O-CB 3.45Å; L126-L131 PolarHBondContact O-N 2.93Å; P127-L131 WeakPolarHBondContact CA-O 3.2Å; L131-L133 HydrophobicContact CD2-CD1 4.33Å; L131-L133 HydrophobicContact CD2-CD2 3.98Å; L131-L133 HydrophobicContact CD2-CG 4.21Å; L131-L133 HydrophobicContact CG-CD2 4.02Å; L131-L133 HydrophobicContact CG-CG 4.17Å; L131-L133 PolarHBondContact O-N 2.96Å; L131-I150 HydrophobicContact CD1-CD1 3.78Å; L131-I150 HydrophobicContact CD1-CG1 4.17Å; L131-A164 HydrophobicContact CD1-CB 3.53Å; L131-L165 HydrophobicContact CD2-CD2 3.62Å; L131-L165 HydrophobicContact CD2-CG 4.16Å
132N92.6Very high95.4Very high88 Ų8837.2 Ų37.247%0.47121%0.206SC..  trans-74.2114.7176.5-176.87.1000110.4S134 I150 P151N132-S134 PolarHBondContact ND2-OG 3.1Å; N132-S134 WeakPolarHBondContact OD1-CB 3.39Å; N132-S134 PolarHBondContact OD1-N 3.1Å; N132-S134 PolarHBondContact OD1-OG 2.87Å; N132-S134 VanDerWaalsContact OD1-OG 3.04Å; N132-I150 WeakPolarHBondContact O-CA 3.42Å; N132-P151 WeakPolarHBondContact ND2-CG 3.32Å; N132-P151 WeakPolarHBondContact O-CD 3.35Å
133L95.2Very high95.4Very high8 Ų839.1 Ų39.14%0.04222%0.222CC..  trans-113.129179-67.4-174.3000112.9I75 L82 V123 L126 L131 Q135 H148 R149 I150 I161I75-L133 HydrophobicContact CG2-CD1 4.15Å; L82-L133 WeakPolarHBondContact CD2-O 3.33Å; V123-L133 HydrophobicContact CG1-CD1 4.16Å; L126-L133 HydrophobicContact CB-CD1 3.97Å; L126-L133 HydrophobicContact CD1-CD1 3.62Å; L126-L133 HydrophobicContact CG-CD1 4.46Å; L131-L133 HydrophobicContact CD2-CD1 4.33Å; L131-L133 HydrophobicContact CD2-CD2 3.98Å; L131-L133 HydrophobicContact CD2-CG 4.21Å; L131-L133 HydrophobicContact CG-CD2 4.02Å; L131-L133 HydrophobicContact CG-CG 4.17Å; L131-L133 PolarHBondContact O-N 2.96Å; L133-Q135 PolarHBondContact O-N 3.02Å; L133-Q135 VanDerWaalsContact O-N 3.16Å; L133-H148 HydrophobicContact CB-CB 4.2Å; L133-H148 HydrophobicContact CD1-CB 4.5Å; L133-R149 CarbonylContact C-O 3.34Å; L133-R149 VanDerWaalsContact C-O 3.3Å; L133-R149 WeakPolarHBondContact CA-O 3.3Å; L133-I150 HydrophobicContact CD2-CG1 4.09Å; L133-I161 HydrophobicContact CD2-CD1 3.68Å; L133-I161 HydrophobicContact CD2-CG1 4.23Å
134S94.1Very high95.3Very high64 Ų6440.6 Ų40.645%0.44823%0.231SC..  trans-76.38.6-171.872.20000116N132N132-S134 PolarHBondContact ND2-OG 3.1Å; N132-S134 WeakPolarHBondContact OD1-CB 3.39Å; N132-S134 PolarHBondContact OD1-N 3.1Å; N132-S134 PolarHBondContact OD1-OG 2.87Å; N132-S134 VanDerWaalsContact OD1-OG 3.04Å
135Q94.1Very high95.3Very high29 Ų2943.8 Ų43.814%0.13624%0.243CC..EExtended strand (participates in β ladder)trans-107.1126.4173.9-178.5-179.169.200109.9L133 H148 R149 P151 F309 K361L133-Q135 PolarHBondContact O-N 3.02Å; L133-Q135 VanDerWaalsContact O-N 3.16Å; Q135-H148 CarbonylContact O-C 3.45Å; Q135-H148 WeakPolarHBondContact O-CA 3.27Å; Q135-R149 HydrophobicContact CB-CB 4.01Å; Q135-R149 HydrophobicContact CG-CB 4.21Å; Q135-R149 PolarHBondContact N-O 3.02Å; Q135-R149 PolarHBondContact O-N 2.91Å; Q135-P151 HydrophobicContact CB-CB 4.21Å; Q135-F309 HydrophobicContact CG-CZ 4.41Å; Q135-K361 PolarHBondContact NE2-O 2.74Å
136L95.6Very high95.3Very high25 Ų2540.4 Ų40.413%0.13123%0.227CC..EExtended strand (participates in β ladder)trans-107.7135.1171.8-76174.2000110.9L82 Q83 V88 K145L82-L136 HydrophobicContact CD2-CD1 4.05Å; L82-L136 HydrophobicContact CD2-CD2 4.09Å; L82-L136 HydrophobicContact CD2-CG 3.6Å; L82-L136 HydrophobicContact CG-CD1 3.87Å; L82-L136 HydrophobicContact CG-CG 4.01Å; Q83-L136 HydrophobicContact CG-CD1 3.84Å; Q83-L136 HydrophobicContact CG-CD2 4.36Å; V88-L136 HydrophobicContact CG2-CD1 4.23Å; L136-K145 HydrophobicContact CB-CB 4.28Å
137V95.7Very high95.4Very high3 Ų340.3 Ų40.32%0.01823%0.227CC..EExtended strand (participates in β ladder)trans-129.9153.1171.871.30000110.3L139 R146 T147 R149 F309V137-L139 HydrophobicContact CG1-CD2 3.66Å; V137-L139 HydrophobicContact CG1-CG 4.17Å; V137-L139 HydrophobicContact CG2-CD2 4.37Å; V137-R146 PolarHBondContact O-N 2.82Å; V137-T147 HydrophobicContact CG1-CG2 4.12Å; V137-T147 PolarHBondContact N-O 3.49Å; V137-T147 PolarHBondContact O-N 2.87Å; V137-R149 VanDerWaalsContact CG1-CD 3.42Å; V137-R149 HydrophobicContact CG1-CG 4.16Å; V137-F309 HydrophobicContact CB-CE1 3.89Å; V137-F309 HydrophobicContact CB-CZ 3.82Å; V137-F309 HydrophobicContact CG2-CD1 3.76Å; V137-F309 HydrophobicContact CG2-CD2 4.35Å; V137-F309 HydrophobicContact CG2-CE1 3.47Å; V137-F309 VanDerWaalsContact CG2-CE1 3.47Å; V137-F309 HydrophobicContact CG2-CE2 4.1Å; V137-F309 HydrophobicContact CG2-CG 4.2Å; V137-F309 HydrophobicContact CG2-CZ 3.65Å
138I96.7Very high95.5Very high17 Ų1737.1 Ų37.19%0.08721%0.206CC..  trans-94.2126.8166.8-172.5164.3000108H142 K145 G308 L325 V419I138-H142 HydrophobicContact CG1-CB 4.05Å; I138-K145 HydrophobicContact CB-CG 3.97Å; I138-G308 WeakPolarHBondContact O-CA 3.32Å; I138-L325 HydrophobicContact CG2-CD1 4.39Å; I138-V419 HydrophobicContact CD1-CG2 4.2Å; I138-V419 HydrophobicContact CG2-CG1 3.82Å
139L97.1Very high95.6Very high0 Ų029.4 Ų29.40%017%0.172CC..  trans-102.5179.3174.4-61.1-169.8000110.1V137 H142 T147 E304 A305V137-L139 HydrophobicContact CG1-CD2 3.66Å; V137-L139 HydrophobicContact CG1-CG 4.17Å; V137-L139 HydrophobicContact CG2-CD2 4.37Å; L139-H142 VanDerWaalsContact C-CD2 3.47Å; L139-H142 PolarHBondContact O-CD2 3.35Å; L139-H142 PolarHBondContact O-N 3.05Å; L139-T147 HydrophobicContact CD1-CG2 3.74Å; L139-T147 HydrophobicContact CG-CG2 4.11Å; L139-T147 WeakPolarHBondContact CG-OG1 3.48Å; L139-E304 HydrophobicContact CB-CG 4.05Å; L139-E304 HydrophobicContact CD1-CB 4.31Å; L139-E304 HydrophobicContact CD1-CG 4.39Å; L139-E304 HydrophobicContact CD2-CB 4.14Å; L139-E304 HydrophobicContact CD2-CG 4.06Å; L139-E304 HydrophobicContact CG-CG 4.39Å; L139-A305 HydrophobicContact CD2-CB 4.21Å
140A95.8Very high95.6Very high4 Ų427.5 Ų27.53%0.03317%0.166CC..THydrogen-bonded Turntrans-69.2137.9-175.300000111.1H142 E304 R307 L325 A326A140-H142 PolarHBondContact O-CD2 3.23Å; A140-H142 PolarHBondContact O-N 3.5Å; A140-E304 WeakPolarHBondContact CA-OE1 3.28Å; A140-E304 HydrophobicContact CB-CG 4.27Å; A140-E304 WeakPolarHBondContact CB-OE1 3.46Å; A140-E304 PolarHBondContact N-OE1 3.29Å; A140-R307 VanDerWaalsContact CB-NH1 3.34Å; A140-L325 CarbonylContact C-O 3.57Å; A140-L325 VanDerWaalsContact CA-O 3.31Å; A140-L325 WeakPolarHBondContact CA-O 3.3Å; A140-L325 HydrophobicContact CB-CD2 4.34Å; A140-A326 WeakPolarHBondContact CB-O 3.46Å
141G95.7Very high95.5Very high20 Ų2026.5 Ų26.521%0.20615%0.151CC..THydrogen-bonded Turntrans78.4-6.8-17700000115.7L325G141-L325 PolarHBondContact N-O 3.44Å
142H97.4Very high94.9Very high16 Ų1629 Ų297%0.07417%0.168CC..  trans-82.6142176-64-102.4000111.4N76 I138 L139 A140 R146 L481 G482N76-H142 PolarHBondContact ND2-CE1 2.96Å; I138-H142 HydrophobicContact CG1-CB 4.05Å; L139-H142 VanDerWaalsContact C-CD2 3.47Å; L139-H142 PolarHBondContact O-CD2 3.35Å; L139-H142 PolarHBondContact O-N 3.05Å; A140-H142 PolarHBondContact O-CD2 3.23Å; A140-H142 PolarHBondContact O-N 3.5Å; H142-R146 PolarHBondContact ND1-NH1 2.84Å; H142-L481 VanDerWaalsContact CE1-CD2 3.48Å; H142-L481 WeakPolarHBondContact CE1-CD2 3.21Å; H142-L481 VanDerWaalsContact CE1-CG 3.44Å; H142-L481 WeakPolarHBondContact CE1-CG 3.17Å; H142-L481 WeakPolarHBondContact NE2-CG 3.46Å; H142-G482 PolarHBondContact CE1-O 2.86Å; H142-G482 VanDerWaalsContact CE1-O 3.29Å; H142-G482 PolarHBondContact NE2-O 3.45Å
143S96.3Very high94.3Very high62 Ų6226.8 Ų26.843%0.43416%0.158SC..SBendtrans-82.1-23.3173.553.30000113.5D98D98-S143 WeakPolarHBondContact OD1-CB 3.49Å; D98-S143 PolarHBondContact OD1-OG 2.82Å; D98-S143 PolarHBondContact OD2-N 2.87Å; D98-S143 PolarHBondContact OD2-OG 3.47Å
144V97Very high93.3Very high33 Ų3334 Ų3420%0.220%0.202CC..SBendtrans-143.6164.2-178.3-64.90000111.3V88 D90 R146V88-V144 HydrophobicContact CG1-CB 4.34Å; D90-V144 HydrophobicContact CB-CG2 3.59Å; D90-V144 VanDerWaalsContact CG-CG2 3.45Å; D90-V144 WeakPolarHBondContact OD1-CG2 3.35Å; V144-R146 PolarHBondContact O-N 3.18Å; V144-R146 VanDerWaalsContact O-N 3.12Å
145K97.4Very high92.5Very high106 Ų10635.1 Ų35.146%0.46120%0.203SC..  trans-64.1111.1173.7-67179.9-176.81760110Q83 V88 L136 I138Q83-K145 PolarHBondContact NE2-O 3.35Å; V88-K145 HydrophobicContact CG1-CB 4.35Å; V88-K145 WeakPolarHBondContact CG1-O 3.49Å; V88-K145 HydrophobicContact CG2-CB 4.39Å; L136-K145 HydrophobicContact CB-CB 4.28Å; I138-K145 HydrophobicContact CB-CG 3.97Å
146R97.3Very high91.5Very high0 Ų036 Ų360%022%0.219CC..  trans-125.7-19.7-175.2-173.6170.9-60.4107.8-15.5113.6N76 A77 D90 F95 D98 V137 H142 V144 H148N76-R146 WeakPolarHBondContact CA-O 3.35Å; N76-R146 HydrophobicContact CB-CG 3.92Å; A77-R146 PolarHBondContact N-O 2.66Å; A77-R146 VanDerWaalsContact O-CG 3.29Å; A77-R146 WeakPolarHBondContact O-CG 3.47Å; D90-R146 VanDerWaalsContact CG-NE 3.32Å; D90-R146 IonicContact OD1-CZ 2.77Å; D90-R146 VanDerWaalsContact OD1-CZ 3.28Å; D90-R146 IonicContact OD1-NE 3.91Å; D90-R146 PolarHBondContact OD1-NE 2.81Å; D90-R146 IonicContact OD1-NH2 2.7Å; D90-R146 PolarHBondContact OD1-NH2 3.48Å; D90-R146 WeakPolarHBondContact OD2-CD 3.19Å; D90-R146 VanDerWaalsContact OD2-CG 3.26Å; D90-R146 WeakPolarHBondContact OD2-CG 3.27Å; D90-R146 IonicContact OD2-CZ 2.72Å; D90-R146 IonicContact OD2-NE 3.63Å; D90-R146 PolarHBondContact OD2-NE 2.97Å; D90-R146 IonicContact OD2-NH2 3.77Å; F95-R146 VanDerWaalsContact CE2-CD 3.48Å; F95-R146 VanDerWaalsContact CG-CD 3.43Å; D98-R146 IonicContact OD2-CZ 2.8Å; D98-R146 VanDerWaalsContact OD2-CZ 3.31Å; D98-R146 IonicContact OD2-NH1 3.16Å; D98-R146 PolarHBondContact OD2-NH1 3.19Å; D98-R146 IonicContact OD2-NH2 3.6Å; D98-R146 PolarHBondContact OD2-NH2 3.01Å; V137-R146 PolarHBondContact O-N 2.82Å; H142-R146 PolarHBondContact ND1-NH1 2.84Å; V144-R146 PolarHBondContact O-N 3.18Å; V144-R146 VanDerWaalsContact O-N 3.12Å; R146-H148 PolarHBondContact O-N 3.48Å; R146-H148 PolarHBondContact O-ND1 2.94Å; R146-H148 VanDerWaalsContact O-ND1 3.13Å
147T98.3Very high90.6Very high0 Ų042.8 Ų42.80%024%0.243CC..EExtended strand (participates in β ladder)trans-93.7107.8-168.6-54.80000109.9G74 I75 N76 V137 L139G74-T147 VanDerWaalsContact CA-CG2 3.42Å; I75-T147 CarbonylContact O-C 3.57Å; I75-T147 WeakPolarHBondContact O-CA 3.45Å; N76-T147 WeakPolarHBondContact OD1-CA 3.5Å; N76-T147 WeakPolarHBondContact OD1-CB 3.46Å; N76-T147 PolarHBondContact OD1-OG1 2.8Å; V137-T147 HydrophobicContact CG1-CG2 4.12Å; V137-T147 PolarHBondContact N-O 3.49Å; V137-T147 PolarHBondContact O-N 2.87Å; L139-T147 HydrophobicContact CD1-CG2 3.74Å; L139-T147 HydrophobicContact CG-CG2 4.11Å; L139-T147 WeakPolarHBondContact CG-OG1 3.48Å
148H97.8Very high89.7Confident2 Ų245 Ų451%0.00926%0.262CS..EExtended strand (participates in β ladder)trans-75.9137.7174-5969.3000111G74 I75 S80 V123 L133 Q135 R146 I161G74-H148 CarbonylContact C-O 3.45Å; G74-H148 WeakPolarHBondContact CA-O 3.29Å; I75-H148 HydrophobicContact CG2-CB 4.03Å; I75-H148 PolarHBondContact N-O 3.46Å; I75-H148 PolarHBondContact O-N 2.78Å; S80-H148 PolarHBondContact OG-CE1 3.44Å; S80-H148 PolarHBondContact OG-NE2 3.33Å; V123-H148 HydrophobicContact CG1-CB 4.38Å; L133-H148 HydrophobicContact CB-CB 4.2Å; L133-H148 HydrophobicContact CD1-CB 4.5Å; Q135-H148 CarbonylContact O-C 3.45Å; Q135-H148 WeakPolarHBondContact O-CA 3.27Å; R146-H148 PolarHBondContact O-N 3.48Å; R146-H148 PolarHBondContact O-ND1 2.94Å; R146-H148 VanDerWaalsContact O-ND1 3.13Å; H148-I161 WeakPolarHBondContact O-CD1 3.28Å
149R95.1Very high89.1Confident15 Ų1546.9 Ų46.96%0.05727%0.274CS..EExtended strand (participates in β ladder)trans-135.1155.4-176.1-70.3178.559.285.83.7110.6S72 S73 L133 Q135 V137S72-R149 PolarHBondContact O-NH1 3.2Å; S73-R149 VanDerWaalsContact C-NH1 3.26Å; S73-R149 VanDerWaalsContact O-CD 3.31Å; S73-R149 WeakPolarHBondContact O-CD 3.36Å; S73-R149 WeakPolarHBondContact O-CG 3.41Å; S73-R149 PolarHBondContact O-NH1 2.9Å; L133-R149 CarbonylContact C-O 3.34Å; L133-R149 VanDerWaalsContact C-O 3.3Å; L133-R149 WeakPolarHBondContact CA-O 3.3Å; Q135-R149 HydrophobicContact CB-CB 4.01Å; Q135-R149 HydrophobicContact CG-CB 4.21Å; Q135-R149 PolarHBondContact N-O 3.02Å; Q135-R149 PolarHBondContact O-N 2.91Å; V137-R149 VanDerWaalsContact CG1-CD 3.42Å; V137-R149 HydrophobicContact CG1-CG 4.16Å
150I92.9Very high88.7Confident26 Ų2648.4 Ų48.413%0.13329%0.286CS..PPolyproline II helixtrans-72.3122.5164-57.1173.3000106.9L131 N132 L133 V159 I161 A164L131-I150 HydrophobicContact CD1-CD1 3.78Å; L131-I150 HydrophobicContact CD1-CG1 4.17Å; N132-I150 WeakPolarHBondContact O-CA 3.42Å; L133-I150 HydrophobicContact CD2-CG1 4.09Å; I150-V159 HydrophobicContact CD1-CB 4.39Å; I150-V159 HydrophobicContact CD1-CG1 3.75Å; I150-I161 HydrophobicContact CD1-CB 4.23Å; I150-I161 HydrophobicContact CD1-CG1 4.37Å; I150-I161 HydrophobicContact CG1-CB 4.32Å; I150-I161 HydrophobicContact CG1-CG1 4.25Å; I150-A164 HydrophobicContact CD1-CB 3.59Å
151P89.5Confident88.6Confident29 Ų2948.4 Ų48.419%0.18829%0.286CS..PPolyproline II helixtrans-64.2163.7174.929.1-35.6000110.8N132 Q135 T153N132-P151 WeakPolarHBondContact ND2-CG 3.32Å; N132-P151 WeakPolarHBondContact O-CD 3.35Å; Q135-P151 HydrophobicContact CB-CB 4.21Å; P151-T153 PolarHBondContact O-N 3.48Å
152P82Confident88.7Confident61 Ų6147.5 Ų47.540%0.39628%0.276SS..PPolyproline II helixtrans-51.4128.7173.9-24.434.5000110.9G363P152-G363 VanDerWaalsContact CG-CA 3.48Å
153T79.1Confident88.6Confident42 Ų4252 Ų5226%0.25830%0.296SS..PPolyproline II helixtrans-77.9143.3-17969.80000110.4P151 D155 G156 R157 V159P151-T153 PolarHBondContact O-N 3.48Å; T153-D155 WeakPolarHBondContact CB-OD1 3.35Å; T153-D155 PolarHBondContact O-N 3.08Å; T153-D155 PolarHBondContact OG1-OD1 3.39Å; T153-G156 PolarHBondContact O-N 3.34Å; T153-R157 PolarHBondContact OG1-N 3.25Å; T153-R157 PolarHBondContact OG1-O 3.14Å; T153-V159 HydrophobicContact CG2-CG2 4.2Å
154V74.7Confident88.6Confident159 Ų15949.5 Ų49.596%0.96428%0.279SS*.THydrogen-bonded Turntrans-64-33.5178.6-172.50000111.4G156V154-G156 PolarHBondContact O-N 3.22Å
155D76.7Confident88.6Confident89 Ų8948 Ų4848%0.47627%0.269SS..THydrogen-bonded Turntrans-80.54-177.967.42.1000114.2T153 R157T153-D155 WeakPolarHBondContact CB-OD1 3.35Å; T153-D155 PolarHBondContact O-N 3.08Å; T153-D155 PolarHBondContact OG1-OD1 3.39Å; D155-R157 VanDerWaalsContact C-N 3.29Å; D155-R157 PolarHBondContact O-N 3.16Å; D155-R157 WeakPolarHBondContact OD1-CB 3.49Å; D155-R157 PolarHBondContact OD1-N 3.02Å; D155-R157 VanDerWaalsContact OD1-N 3.1Å; D155-R157 IonicContact OD1-NE 3.44Å; D155-R157 IonicContact OD2-CZ 3.05Å; D155-R157 IonicContact OD2-NE 3.65Å; D155-R157 PolarHBondContact OD2-NE 3.33Å; D155-R157 IonicContact OD2-NH2 3.09Å; D155-R157 PolarHBondContact OD2-NH2 2.96Å
156G74Confident88.7Confident46 Ų4643.2 Ų43.247%0.47425%0.249SC..  trans73.915175.600000114.8T153 V154 P365T153-G156 PolarHBondContact O-N 3.34Å; V154-G156 PolarHBondContact O-N 3.22Å; G156-P365 WeakPolarHBondContact O-CB 3.23Å; G156-P365 WeakPolarHBondContact O-CG 3.31Å
157R77.2Confident88.7Confident169 Ų16948.3 Ų48.364%0.63827%0.273SS*.  trans-89.4126.9176.5-69.4-171.5-70.6169.1-4.6112.5T153 D155 V159T153-R157 PolarHBondContact OG1-N 3.25Å; T153-R157 PolarHBondContact OG1-O 3.14Å; D155-R157 VanDerWaalsContact C-N 3.29Å; D155-R157 PolarHBondContact O-N 3.16Å; D155-R157 WeakPolarHBondContact OD1-CB 3.49Å; D155-R157 PolarHBondContact OD1-N 3.02Å; D155-R157 VanDerWaalsContact OD1-N 3.1Å; D155-R157 IonicContact OD1-NE 3.44Å; D155-R157 IonicContact OD2-CZ 3.05Å; D155-R157 IonicContact OD2-NE 3.65Å; D155-R157 PolarHBondContact OD2-NE 3.33Å; D155-R157 IonicContact OD2-NH2 3.09Å; D155-R157 PolarHBondContact OD2-NH2 2.96Å; R157-V159 PolarHBondContact O-N 3.43Å
158A76.1Confident88.6Confident50 Ų5051.2 Ų51.241%0.41328%0.284SS..  trans-70.7119.717000000110.1P365A158-P365 HydrophobicContact CB-CB 4.11Å
159V83.2Confident88.7Confident56 Ų5651.6 Ų51.634%0.33929%0.285SS..  trans-121.3111.6177.4-175.40000109.7I150 T153 R157 I161 A164I150-V159 HydrophobicContact CD1-CB 4.39Å; I150-V159 HydrophobicContact CD1-CG1 3.75Å; T153-V159 HydrophobicContact CG2-CG2 4.2Å; R157-V159 PolarHBondContact O-N 3.43Å; V159-I161 PolarHBondContact O-N 2.85Å; V159-A164 HydrophobicContact CG1-CB 3.88Å
160A89.6Confident88.8Confident31 Ų3152.9 Ų52.926%0.25629%0.29SS..  trans-68.3125.3168.400000109.2G162 K163 A164A160-G162 PolarHBondContact O-N 3.49Å; A160-K163 HydrophobicContact CB-CB 4.23Å; A160-K163 WeakPolarHBondContact O-CB 3.46Å; A160-K163 PolarHBondContact O-N 3.25Å; A160-K163 VanDerWaalsContact O-N 3.1Å; A160-A164 PolarHBondContact O-N 2.93Å; A160-A164 VanDerWaalsContact O-N 3.07Å
161I94Very high88.9Confident5 Ų553.4 Ų53.43%0.02630%0.295CS..Hα-helixtrans-54.6-39.8179.4-174.1174.6000112.2I75 L133 H148 I150 V159 K163 A164 L165 L486I75-I161 HydrophobicContact CB-CD1 4.22Å; I75-I161 HydrophobicContact CG2-CD1 3.71Å; L133-I161 HydrophobicContact CD2-CD1 3.68Å; L133-I161 HydrophobicContact CD2-CG1 4.23Å; H148-I161 WeakPolarHBondContact O-CD1 3.28Å; I150-I161 HydrophobicContact CD1-CB 4.23Å; I150-I161 HydrophobicContact CD1-CG1 4.37Å; I150-I161 HydrophobicContact CG1-CB 4.32Å; I150-I161 HydrophobicContact CG1-CG1 4.25Å; V159-I161 PolarHBondContact O-N 2.85Å; I161-K163 PolarHBondContact O-N 2.9Å; I161-A164 PolarHBondContact O-N 3.42Å; I161-L165 HydrophobicContact CG1-CD1 4.03Å; I161-L165 HydrophobicContact CG1-CG 4.24Å; I161-L165 VanDerWaalsContact O-CG 3.32Å; I161-L165 WeakPolarHBondContact O-CG 3.43Å; I161-L165 PolarHBondContact O-N 3.13Å; I161-L486 HydrophobicContact CG2-CD1 4.12Å
162G96.7Very high89.2Confident0 Ų052.4 Ų52.40%029%0.288CS..Hα-helixtrans-60.7-44.2178.100000113S68 A71 A160 A164 L165 V166S68-G162 CarbonylContact O-C 3.58Å; S68-G162 WeakPolarHBondContact O-CA 3.37Å; A71-G162 PolarHBondContact O-N 3.37Å; A160-G162 PolarHBondContact O-N 3.49Å; G162-A164 VanDerWaalsContact C-N 3.33Å; G162-A164 PolarHBondContact O-N 3.5Å; G162-L165 PolarHBondContact O-N 3.17Å; G162-V166 WeakPolarHBondContact O-CG2 3.4Å; G162-V166 PolarHBondContact O-N 3.47Å
163K95.7Very high89.9Confident112 Ų11249.5 Ų49.549%0.48727%0.269SS..Hα-helixtrans-61.2-43.4173.6-174173.4-178.7175.90111.5A69 A160 I161 V166 Q167A69-K163 WeakPolarHBondContact O-CB 3.42Å; A69-K163 PolarHBondContact O-N 2.83Å; A160-K163 HydrophobicContact CB-CB 4.23Å; A160-K163 WeakPolarHBondContact O-CB 3.46Å; A160-K163 PolarHBondContact O-N 3.25Å; A160-K163 VanDerWaalsContact O-N 3.1Å; I161-K163 PolarHBondContact O-N 2.9Å; K163-V166 PolarHBondContact O-N 3.35Å; K163-Q167 WeakPolarHBondContact O-CB 3.29Å; K163-Q167 VanDerWaalsContact O-CG 3.28Å; K163-Q167 WeakPolarHBondContact O-CG 3.46Å; K163-Q167 PolarHBondContact O-N 3.19Å
164A95.8Very high90.5Very high9 Ų951.4 Ų51.47%0.07428%0.275CS..Hα-helixtrans-66.8-37.6-18000000112.5L131 I150 V159 A160 I161 G162 R168L131-A164 HydrophobicContact CD1-CB 3.53Å; I150-A164 HydrophobicContact CD1-CB 3.59Å; V159-A164 HydrophobicContact CG1-CB 3.88Å; A160-A164 PolarHBondContact O-N 2.93Å; A160-A164 VanDerWaalsContact O-N 3.07Å; I161-A164 PolarHBondContact O-N 3.42Å; G162-A164 VanDerWaalsContact C-N 3.33Å; G162-A164 PolarHBondContact O-N 3.5Å; A164-R168 VanDerWaalsContact O-CB 3.3Å; A164-R168 WeakPolarHBondContact O-CB 3.42Å; A164-R168 PolarHBondContact O-N 3.3Å
165L98.2Very high91.3Very high0 Ų046.6 Ų46.60%024%0.243CC..Hα-helixtrans-62.9-51.1172.9-72.2167.4000111.1L39 I75 L126 L131 I161 G162 Q167 R168 Y169 L486 I490L39-L165 HydrophobicContact CD1-CB 4.2Å; L39-L165 HydrophobicContact CD2-CB 4.26Å; L39-L165 HydrophobicContact CD2-CD1 4.3Å; I75-L165 HydrophobicContact CD1-CD1 4.33Å; L126-L165 HydrophobicContact CD1-CD2 3.47Å; L126-L165 VanDerWaalsContact CD1-CD2 3.47Å; L126-L165 HydrophobicContact CD2-CD2 3.85Å; L126-L165 HydrophobicContact CG-CD2 4.33Å; L131-L165 HydrophobicContact CD2-CD2 3.62Å; L131-L165 HydrophobicContact CD2-CG 4.16Å; I161-L165 HydrophobicContact CG1-CD1 4.03Å; I161-L165 HydrophobicContact CG1-CG 4.24Å; I161-L165 VanDerWaalsContact O-CG 3.32Å; I161-L165 WeakPolarHBondContact O-CG 3.43Å; I161-L165 PolarHBondContact O-N 3.13Å; G162-L165 PolarHBondContact O-N 3.17Å; L165-Q167 VanDerWaalsContact C-N 3.31Å; L165-Q167 PolarHBondContact O-N 2.98Å; L165-R168 PolarHBondContact O-N 2.83Å; L165-R168 VanDerWaalsContact O-N 3.12Å; L165-Y169 HydrophobicContact CD2-CE2 4.19Å; L165-Y169 WeakPolarHBondContact O-CD2 3.31Å; L165-Y169 PolarHBondContact O-N 3.26Å; L165-L486 HydrophobicContact CD1-CB 4.25Å; L165-L486 HydrophobicContact CD1-CD1 3.76Å; L165-L486 HydrophobicContact CD1-CD2 4.03Å; L165-L486 HydrophobicContact CD1-CG 4.24Å; L165-I490 HydrophobicContact CD2-CD1 4.29Å
166V98.3Very high92Very high6 Ų642.7 Ų42.74%0.03622%0.224CC..Hα-helixtrans-53.1-50.3176.5164.40000110.6L39 I42 I64 A69 G162 K163 R168 Y170L39-V166 HydrophobicContact CB-CG2 4.31Å; I42-V166 HydrophobicContact CD1-CB 4.42Å; I42-V166 HydrophobicContact CD1-CG1 3.75Å; I64-V166 HydrophobicContact CD1-CG1 4.17Å; I64-V166 HydrophobicContact CG1-CG1 4.25Å; A69-V166 HydrophobicContact CB-CG2 4.44Å; G162-V166 WeakPolarHBondContact O-CG2 3.4Å; G162-V166 PolarHBondContact O-N 3.47Å; K163-V166 PolarHBondContact O-N 3.35Å; V166-R168 VanDerWaalsContact C-N 3.35Å; V166-R168 PolarHBondContact O-N 2.79Å; V166-Y170 VanDerWaalsContact O-CB 3.25Å; V166-Y170 WeakPolarHBondContact O-CB 3.46Å; V166-Y170 PolarHBondContact O-N 3.2Å
167Q97.3Very high92.7Very high108 Ų10841.4 Ų41.451%0.50521%0.208SC..Hα-helixtrans-60.4-44.4178.5-73.7173.6-23.900111.8K163 L165 Y170 T171K163-Q167 WeakPolarHBondContact O-CB 3.29Å; K163-Q167 VanDerWaalsContact O-CG 3.28Å; K163-Q167 WeakPolarHBondContact O-CG 3.46Å; K163-Q167 PolarHBondContact O-N 3.19Å; L165-Q167 VanDerWaalsContact C-N 3.31Å; L165-Q167 PolarHBondContact O-N 2.98Å; Q167-Y170 PolarHBondContact O-N 2.97Å; Q167-T171 PolarHBondContact O-N 2.86Å; Q167-T171 PolarHBondContact O-OG1 3.45Å
168R97.2Very high93Very high60 Ų6038.3 Ų38.323%0.22620%0.2CC..Hα-helixtrans-70.5-44.8-175.3-162.965.575.2174.611.3112.7W129 G130 A164 L165 V166 Y170 T171 M172W129-R168 HydrophobicContact CB-CG 3.71Å; W129-R168 WeakPolarHBondContact O-CD 3.41Å; W129-R168 PolarHBondContact O-NE 2.86Å; W129-R168 PolarHBondContact O-NH1 2.93Å; W129-R168 PolarHBondContact O-NH2 3.27Å; G130-R168 PolarHBondContact O-NH2 2.84Å; A164-R168 VanDerWaalsContact O-CB 3.3Å; A164-R168 WeakPolarHBondContact O-CB 3.42Å; A164-R168 PolarHBondContact O-N 3.3Å; L165-R168 PolarHBondContact O-N 2.83Å; L165-R168 VanDerWaalsContact O-N 3.12Å; V166-R168 VanDerWaalsContact C-N 3.35Å; V166-R168 PolarHBondContact O-N 2.79Å; R168-Y170 VanDerWaalsContact C-N 3.3Å; R168-Y170 PolarHBondContact O-N 3.39Å; R168-T171 PolarHBondContact O-N 3.08Å; R168-M172 HydrophobicContact CG-CE 3.98Å; R168-M172 WeakPolarHBondContact O-CG 3.24Å; R168-M172 PolarHBondContact O-N 2.8Å; R168-M172 VanDerWaalsContact O-N 3.09Å
169Y98.3Very high93.1Very high10 Ų1045.2 Ų45.24%0.03922%0.215CC..Hα-helixtrans-65.3-34.8174.9-84.5-80.5000111.9L39 C43 L46 L126 L165 M172 V173 I490L39-Y169 HydrophobicContact CD1-CD2 3.78Å; L39-Y169 HydrophobicContact CD1-CE2 4.45Å; L39-Y169 HydrophobicContact CD1-CG 4.25Å; C43-Y169 VanDerWaalsContact SG-CD1 3.51Å; L46-Y169 HydrophobicContact CD2-CD1 3.9Å; L46-Y169 HydrophobicContact CD2-CE1 4.3Å; L126-Y169 HydrophobicContact CD2-CE2 3.8Å; L165-Y169 HydrophobicContact CD2-CE2 4.19Å; L165-Y169 WeakPolarHBondContact O-CD2 3.31Å; L165-Y169 PolarHBondContact O-N 3.26Å; Y169-M172 HydrophobicContact CD1-SD 3.71Å; Y169-M172 HydrophobicContact CE1-SD 3.98Å; Y169-M172 HydrophobicContact CG-SD 4.26Å; Y169-M172 WeakPolarHBondContact O-CB 3.25Å; Y169-M172 PolarHBondContact O-N 3.3Å; Y169-M172 VanDerWaalsContact O-N 3.17Å; Y169-V173 PolarHBondContact O-N 3.18Å; Y169-I490 HydrophobicContact CE1-CG2 4.29Å; Y169-I490 HydrophobicContact CE2-CD1 3.59Å; Y169-I490 HydrophobicContact CE2-CG1 3.79Å; Y169-I490 HydrophobicContact CE2-CG2 4.46Å; Y169-I490 WeakPolarHBondContact OH-CG2 3.33Å
170Y97.8Very high92.3Very high42 Ų4243.8 Ų43.817%0.16521%0.206CC..Hα-helixtrans-67.6-39.3175.4-168.1-101.8000112.1I42 I64 V166 Q167 R168 M172 V173 E174 F186 L188I42-Y170 HydrophobicContact CG2-CD2 4.48Å; I64-Y170 HydrophobicContact CD1-CD1 3.94Å; I64-Y170 HydrophobicContact CD1-CD2 3.45Å; I64-Y170 VanDerWaalsContact CD1-CD2 3.45Å; I64-Y170 HydrophobicContact CD1-CE1 4.38Å; I64-Y170 HydrophobicContact CD1-CE2 3.94Å; I64-Y170 HydrophobicContact CD1-CG 3.44Å; I64-Y170 VanDerWaalsContact CD1-CG 3.44Å; V166-Y170 VanDerWaalsContact O-CB 3.25Å; V166-Y170 WeakPolarHBondContact O-CB 3.46Å; V166-Y170 PolarHBondContact O-N 3.2Å; Q167-Y170 PolarHBondContact O-N 2.97Å; R168-Y170 VanDerWaalsContact C-N 3.3Å; R168-Y170 PolarHBondContact O-N 3.39Å; Y170-M172 VanDerWaalsContact C-N 3.25Å; Y170-M172 PolarHBondContact O-N 3.09Å; Y170-V173 WeakPolarHBondContact O-CA 3.21Å; Y170-V173 WeakPolarHBondContact O-CB 3.39Å; Y170-V173 PolarHBondContact O-N 3.33Å; Y170-E174 HydrophobicContact CD1-CG 4.14Å; Y170-E174 HydrophobicContact CE1-CG 3.85Å; Y170-E174 WeakPolarHBondContact CE1-OE1 3.44Å; Y170-E174 WeakPolarHBondContact O-CG 3.28Å; Y170-E174 PolarHBondContact O-N 3.46Å; Y170-F186 HydrophobicContact CE2-CZ 4.35Å; Y170-L188 HydrophobicContact CE2-CD2 4.3Å; Y170-L188 WeakPolarHBondContact OH-CD2 3.37Å
171T95.9Very high90.6Very high37 Ų3745.4 Ų45.423%0.22722%0.216CC..Hα-helixtrans-59.1-37169.7-60.90000112.1Q167 R168 V173 E174 L175Q167-T171 PolarHBondContact O-N 2.86Å; Q167-T171 PolarHBondContact O-OG1 3.45Å; R168-T171 PolarHBondContact O-N 3.08Å; T171-V173 VanDerWaalsContact C-N 3.35Å; T171-E174 PolarHBondContact O-N 3.18Å; T171-L175 HydrophobicContact CG2-CD1 4.09Å; T171-L175 WeakPolarHBondContact O-CB 3.35Å; T171-L175 VanDerWaalsContact O-CG 3.29Å; T171-L175 WeakPolarHBondContact O-CG 3.36Å; T171-L175 PolarHBondContact O-N 3.06Å
172M95.2Very high88.7Confident8 Ų850.1 Ų50.14%0.03926%0.255CS..Hα-helixtrans-64.9-39.1173.7-61.7167.9-16900111.8L46 L126 W129 R168 Y169 Y170 L175 A176L46-M172 HydrophobicContact CD1-CB 3.93Å; L46-M172 HydrophobicContact CD2-CB 3.73Å; L46-M172 HydrophobicContact CD2-CG 4.44Å; L46-M172 HydrophobicContact CD2-SD 3.81Å; L46-M172 HydrophobicContact CG-CB 4.48Å; L126-M172 HydrophobicContact CD2-CE 4.48Å; W129-M172 HydrophobicContact CB-CE 3.75Å; W129-M172 HydrophobicContact CD2-CE 3.45Å; W129-M172 VanDerWaalsContact CD2-CE 3.45Å; W129-M172 HydrophobicContact CD2-CG 3.86Å; W129-M172 HydrophobicContact CD2-SD 4.29Å; W129-M172 HydrophobicContact CE3-CE 4.21Å; W129-M172 HydrophobicContact CE3-CG 3.83Å; W129-M172 HydrophobicContact CG-CE 3.19Å; W129-M172 HydrophobicContact CH2-CB 4.43Å; W129-M172 HydrophobicContact CH2-CG 3.8Å; W129-M172 HydrophobicContact CZ2-CG 3.82Å; W129-M172 HydrophobicContact CZ2-SD 4.41Å; W129-M172 HydrophobicContact CZ3-CG 3.81Å; R168-M172 HydrophobicContact CG-CE 3.98Å; R168-M172 WeakPolarHBondContact O-CG 3.24Å; R168-M172 PolarHBondContact O-N 2.8Å; R168-M172 VanDerWaalsContact O-N 3.09Å; Y169-M172 HydrophobicContact CD1-SD 3.71Å; Y169-M172 HydrophobicContact CE1-SD 3.98Å; Y169-M172 HydrophobicContact CG-SD 4.26Å; Y169-M172 WeakPolarHBondContact O-CB 3.25Å; Y169-M172 PolarHBondContact O-N 3.3Å; Y169-M172 VanDerWaalsContact O-N 3.17Å; Y170-M172 VanDerWaalsContact C-N 3.25Å; Y170-M172 PolarHBondContact O-N 3.09Å; M172-L175 PolarHBondContact O-N 2.84Å; M172-A176 WeakPolarHBondContact O-CB 3.47Å; M172-A176 PolarHBondContact O-N 3.19Å
173V95.7Very high86.7Confident0 Ų056.4 Ų56.40%029%0.285CS..Hα-helixtrans-60.1-48.8173.6165.40000110.7I42 T45 L46 L49 Y169 Y170 T171 L175 A176 A177 F186I42-V173 HydrophobicContact CG2-CG2 3.93Å; I42-V173 WeakPolarHBondContact O-CG2 3.36Å; T45-V173 HydrophobicContact CG2-CG1 3.71Å; T45-V173 HydrophobicContact CG2-CG2 4.02Å; L46-V173 HydrophobicContact CB-CG2 3.8Å; L49-V173 HydrophobicContact CD1-CG1 3.83Å; Y169-V173 PolarHBondContact O-N 3.18Å; Y170-V173 WeakPolarHBondContact O-CA 3.21Å; Y170-V173 WeakPolarHBondContact O-CB 3.39Å; Y170-V173 PolarHBondContact O-N 3.33Å; T171-V173 VanDerWaalsContact C-N 3.35Å; V173-L175 VanDerWaalsContact C-N 3.3Å; V173-L175 PolarHBondContact O-N 3.28Å; V173-A176 PolarHBondContact O-N 2.78Å; V173-A177 WeakPolarHBondContact O-CB 3.27Å; V173-A177 PolarHBondContact O-N 2.96Å; V173-F186 HydrophobicContact CG1-CD1 4.11Å; V173-F186 HydrophobicContact CG1-CD2 4.42Å; V173-F186 HydrophobicContact CG1-CE1 3.68Å; V173-F186 HydrophobicContact CG1-CE2 4.04Å; V173-F186 HydrophobicContact CG1-CG 4.47Å; V173-F186 HydrophobicContact CG1-CZ 3.65Å
174E93.1Very high84.8Confident83 Ų8352.7 Ų52.739%0.38828%0.279SS..Hα-helixtrans-59.3-41.9178.1-68.9178.113700111.7Y170 T171 F178Y170-E174 HydrophobicContact CD1-CG 4.14Å; Y170-E174 HydrophobicContact CE1-CG 3.85Å; Y170-E174 WeakPolarHBondContact CE1-OE1 3.44Å; Y170-E174 WeakPolarHBondContact O-CG 3.28Å; Y170-E174 PolarHBondContact O-N 3.46Å; T171-E174 PolarHBondContact O-N 3.18Å; E174-F178 WeakPolarHBondContact O-CB 3.44Å; E174-F178 PolarHBondContact O-N 2.69Å
175L90.8Very high84Confident57 Ų5753.4 Ų53.430%0.29828%0.28SS..Hα-helixtrans-69.2-38.2177-71.1169.3000112.9W129 T171 M172 V173 F178 R179W129-L175 HydrophobicContact CH2-CD1 4.08Å; W129-L175 HydrophobicContact CZ3-CD1 3.58Å; T171-L175 HydrophobicContact CG2-CD1 4.09Å; T171-L175 WeakPolarHBondContact O-CB 3.35Å; T171-L175 VanDerWaalsContact O-CG 3.29Å; T171-L175 WeakPolarHBondContact O-CG 3.36Å; T171-L175 PolarHBondContact O-N 3.06Å; M172-L175 PolarHBondContact O-N 2.84Å; V173-L175 VanDerWaalsContact C-N 3.3Å; V173-L175 PolarHBondContact O-N 3.28Å; L175-F178 PolarHBondContact O-N 2.97Å; L175-R179 WeakPolarHBondContact O-CG 3.46Å; L175-R179 PolarHBondContact O-N 2.88Å
176A90.6Very high83.7Confident8 Ų855 Ų557%0.06629%0.288CS..Hα-helixtrans-65.5-45.6175.600000110.9L46 L49 M172 V173 F178 R179 T180L46-A176 HydrophobicContact CD1-CB 3.9Å; L49-A176 HydrophobicContact CB-CB 4.06Å; L49-A176 HydrophobicContact CD1-CB 4.32Å; M172-A176 WeakPolarHBondContact O-CB 3.47Å; M172-A176 PolarHBondContact O-N 3.19Å; V173-A176 PolarHBondContact O-N 2.78Å; A176-F178 VanDerWaalsContact C-N 3.29Å; A176-F178 PolarHBondContact O-N 2.59Å; A176-R179 PolarHBondContact O-N 3.45Å; A176-T180 PolarHBondContact O-N 3.39Å; A176-T180 PolarHBondContact O-OG1 2.77Å
177A89.2Confident83.4Confident18 Ų1858.5 Ų58.515%0.14930%0.3CS..Hα-helixtrans-62.1-35.1175.100000112.6L49 V173 T180 F186L49-A177 HydrophobicContact CD1-CB 4.32Å; V173-A177 WeakPolarHBondContact O-CB 3.27Å; V173-A177 PolarHBondContact O-N 2.96Å; A177-T180 PolarHBondContact O-OG1 2.68Å; A177-F186 HydrophobicContact CB-CB 3.6Å; A177-F186 HydrophobicContact CB-CD1 4.02Å; A177-F186 HydrophobicContact CB-CG 4.13Å
178F85.1Confident83.4Confident105 Ų10555.8 Ų55.846%0.46129%0.289SS..Hα-helixtrans-71-37.3175.7-175.2-96.1000112.6L18 E174 L175 A176 T180 S181L18-F178 HydrophobicContact CD2-CE2 3.91Å; L18-F178 HydrophobicContact CD2-CZ 4.13Å; E174-F178 WeakPolarHBondContact O-CB 3.44Å; E174-F178 PolarHBondContact O-N 2.69Å; L175-F178 PolarHBondContact O-N 2.97Å; A176-F178 VanDerWaalsContact C-N 3.29Å; A176-F178 PolarHBondContact O-N 2.59Å; F178-T180 PolarHBondContact O-N 2.84Å; F178-S181 WeakPolarHBondContact O-CB 3.4Å; F178-S181 PolarHBondContact O-N 2.96Å; F178-S181 PolarHBondContact O-OG 2.93Å
179R77.2Confident83.2Confident195 Ų19553.7 Ų53.774%0.73628%0.282SS*.Hα-helixtrans-65-24.4-179.9-74.9172.3-174-177.62.7113.3L175 A176L175-R179 WeakPolarHBondContact O-CG 3.46Å; L175-R179 PolarHBondContact O-N 2.88Å; A176-R179 PolarHBondContact O-N 3.45Å
180T66.6Low83.1Confident25 Ų2555.5 Ų55.515%0.15329%0.294CS..THydrogen-bonded Turntrans-96.50.4-179.559.80000112.8A176 A177 F178 A182 Q183A176-T180 PolarHBondContact O-N 3.39Å; A176-T180 PolarHBondContact O-OG1 2.77Å; A177-T180 PolarHBondContact O-OG1 2.68Å; F178-T180 PolarHBondContact O-N 2.84Å; T180-A182 PolarHBondContact O-N 3.4Å; T180-Q183 PolarHBondContact O-N 2.86Å; T180-Q183 VanDerWaalsContact O-O 3.13Å
181S53.2Low83Confident65 Ų6556.3 Ų56.346%0.45530%0.301SS..THydrogen-bonded Turntrans-64.15.5-166.268.60000117.6F178 Q183F178-S181 WeakPolarHBondContact O-CB 3.4Å; F178-S181 PolarHBondContact O-N 2.96Å; F178-S181 PolarHBondContact O-OG 2.93Å; S181-Q183 PolarHBondContact O-N 3.44Å
182A55.1Low83Confident104 Ų10455.1 Ų55.186%0.8629%0.294SS*.THydrogen-bonded Turntrans-63.8-18.2159.100000111.5T180T180-A182 PolarHBondContact O-N 3.4Å
183Q53.7Low83.1Confident132 Ų13256 Ų5662%0.61730%0.303SS*.SBendtrans-141.2130.7176.6-70.5174.717.600108.4T180 S181 H185T180-Q183 PolarHBondContact O-N 2.86Å; T180-Q183 VanDerWaalsContact O-O 3.13Å; S181-Q183 PolarHBondContact O-N 3.44Å; Q183-H185 WeakPolarHBondContact CB-NE2 3.4Å; Q183-H185 PolarHBondContact O-CD2 2.76Å; Q183-H185 PolarHBondContact O-N 3.08Å; Q183-H185 PolarHBondContact O-NE2 3.1Å
184G57.2Low83.1Confident35 Ų3556.6 Ų56.636%0.36131%0.307SS..  trans-76.982.3-166.900000114.8
185H78.3Confident83.1Confident23 Ų2355.1 Ų55.111%0.10630%0.304CS..  trans-95.22-166.1-62.7-67.8000117.4L49 N54 V55 Q183L49-H185 HydrophobicContact CD2-CB 4.49Å; N54-H185 CarbonylContact C-O 3.53Å; N54-H185 WeakPolarHBondContact CA-O 3.33Å; N54-H185 VanDerWaalsContact CG-ND1 3.27Å; N54-H185 PolarHBondContact OD1-ND1 2.95Å; V55-H185 PolarHBondContact N-O 3.17Å; Q183-H185 WeakPolarHBondContact CB-NE2 3.4Å; Q183-H185 PolarHBondContact O-CD2 2.76Å; Q183-H185 PolarHBondContact O-N 3.08Å; Q183-H185 PolarHBondContact O-NE2 3.1Å
186F92.1Very high83.3Confident35 Ų3554.4 Ų54.415%0.15430%0.304CS..EExtended strand (participates in β ladder)trans-134.3132.6-178.8177.7-122.8000113.3T45 L49 V55 L57 Y170 V173 A177 L188T45-F186 HydrophobicContact CG2-CD2 3.83Å; T45-F186 HydrophobicContact CG2-CE2 3.45Å; T45-F186 VanDerWaalsContact CG2-CE2 3.45Å; T45-F186 HydrophobicContact CG2-CZ 4.24Å; L49-F186 HydrophobicContact CD1-CB 4.45Å; L49-F186 HydrophobicContact CD1-CD2 4.35Å; L49-F186 HydrophobicContact CD1-CG 4.37Å; L49-F186 HydrophobicContact CD2-CB 4.11Å; V55-F186 HydrophobicContact CB-CD2 4.46Å; V55-F186 WeakPolarHBondContact O-CA 3.06Å; L57-F186 HydrophobicContact CB-CE2 3.9Å; L57-F186 HydrophobicContact CB-CZ 4.46Å; Y170-F186 HydrophobicContact CE2-CZ 4.35Å; V173-F186 HydrophobicContact CG1-CD1 4.11Å; V173-F186 HydrophobicContact CG1-CD2 4.42Å; V173-F186 HydrophobicContact CG1-CE1 3.68Å; V173-F186 HydrophobicContact CG1-CE2 4.04Å; V173-F186 HydrophobicContact CG1-CG 4.47Å; V173-F186 HydrophobicContact CG1-CZ 3.65Å; A177-F186 HydrophobicContact CB-CB 3.6Å; A177-F186 HydrophobicContact CB-CD1 4.02Å; A177-F186 HydrophobicContact CB-CG 4.13Å; F186-L188 HydrophobicContact CZ-CB 4.09Å
187R92.6Very high83.7Confident78 Ų7854.9 Ų54.929%0.29431%0.305SS..EExtended strand (participates in β ladder)trans-133.7132.1172.3-171.3175.3-178.6179.8-1.5111V55 T56 L57 L189V55-R187 PolarHBondContact O-N 3.49Å; T56-R187 CarbonylContact C-O 3.58Å; T56-R187 WeakPolarHBondContact CA-O 3.42Å; T56-R187 HydrophobicContact CG2-CB 4.5Å; L57-R187 PolarHBondContact N-O 3.47Å; R187-L189 HydrophobicContact CG-CD2 4.19Å; R187-L189 HydrophobicContact CG-CG 4.27Å
188L95.4Very high83.9Confident52 Ų5254.5 Ų54.527%0.27230%0.301SS..EExtended strand (participates in β ladder)trans-102.7126.9165.8174.162.4000109.3L57 I64 Y170 F186 T190L57-L188 HydrophobicContact CB-CD1 4.26Å; L57-L188 HydrophobicContact CD2-CD1 4.03Å; L57-L188 HydrophobicContact CG-CD1 3.93Å; L57-L188 CarbonylContact O-C 3.53Å; L57-L188 WeakPolarHBondContact O-CA 3.4Å; I64-L188 HydrophobicContact CG2-CD1 4.22Å; I64-L188 HydrophobicContact CG2-CD2 3.98Å; Y170-L188 HydrophobicContact CE2-CD2 4.3Å; Y170-L188 WeakPolarHBondContact OH-CD2 3.37Å; F186-L188 HydrophobicContact CZ-CB 4.09Å; L188-T190 HydrophobicContact CD1-CG2 4.23Å; L188-T190 HydrophobicContact CD2-CG2 4.04Å; L188-T190 HydrophobicContact CG-CG2 4.04Å
189L94.8Very high84.2Confident16 Ų1652.8 Ų52.88%0.08430%0.299CS..EExtended strand (participates in β ladder)trans-113.995.7173-67.3-178.2000109.1T56 L57 I58 E59 R187 T192 I220T56-L189 HydrophobicContact CG2-CD1 3.76Å; T56-L189 HydrophobicContact CG2-CG 4.1Å; L57-L189 PolarHBondContact O-N 2.98Å; I58-L189 CarbonylContact C-O 3.26Å; I58-L189 HydrophobicContact CG1-CB 4.44Å; I58-L189 HydrophobicContact CG1-CD1 4.39Å; E59-L189 PolarHBondContact N-O 3.42Å; R187-L189 HydrophobicContact CG-CD2 4.19Å; R187-L189 HydrophobicContact CG-CG 4.27Å; L189-T192 HydrophobicContact CB-CG2 4.38Å; L189-I220 HydrophobicContact CD1-CD1 3.67Å
190T96.3Very high84.8Confident48 Ų4846.3 Ų46.329%0.29428%0.284SS..  trans-82.5169169.352.70000110.9E59 E61 L188 T192E59-T190 HydrophobicContact CB-CG2 4.34Å; E59-T190 CarbonylContact O-C 3.56Å; E59-T190 VanDerWaalsContact O-C 3.25Å; E59-T190 VanDerWaalsContact O-CA 3.3Å; E59-T190 WeakPolarHBondContact O-CA 3.24Å; E61-T190 WeakPolarHBondContact O-CB 3.44Å; L188-T190 HydrophobicContact CD1-CG2 4.23Å; L188-T190 HydrophobicContact CD2-CG2 4.04Å; L188-T190 HydrophobicContact CG-CG2 4.04Å; T190-T192 PolarHBondContact O-N 3.24Å; T190-T192 PolarHBondContact O-OG1 3Å
191N95.7Very high85.7Confident59 Ų5954.3 Ų54.332%0.31632%0.317SS..SBendtrans52.729.6-177.3-58.6-60.6000112.5E59 M60 E61 S62 D211 V212E59-N191 PolarHBondContact O-N 3.07Å; M60-N191 WeakPolarHBondContact O-CA 3.18Å; E61-N191 PolarHBondContact O-N 3.08Å; S62-N191 VanDerWaalsContact CA-OD1 3.32Å; S62-N191 WeakPolarHBondContact CA-OD1 3.45Å; S62-N191 WeakPolarHBondContact CB-OD1 3.4Å; S62-N191 PolarHBondContact N-OD1 3.13Å; N191-D211 VanDerWaalsContact O-OD1 3.06Å; N191-V212 HydrophobicContact CB-CG1 4.35Å; N191-V212 HydrophobicContact CB-CG2 3.73Å; N191-V212 WeakPolarHBondContact O-CG1 3.4Å; N191-V212 PolarHBondContact O-N 2.96Å
192T95.9Very high87.1Confident11 Ų1156.1 Ų56.17%0.06732%0.318CS..EExtended strand (participates in β ladder)trans-129.4114.1-174.2-59.80000108.6I58 E59 M60 L189 T190 V209 K210I58-T192 HydrophobicContact CG2-CG2 3.95Å; I58-T192 WeakPolarHBondContact CG2-O 3.47Å; E59-T192 CarbonylContact C-O 3.54Å; E59-T192 VanDerWaalsContact C-O 3.26Å; E59-T192 PolarHBondContact O-N 3.04Å; E59-T192 VanDerWaalsContact O-O 3.11Å; M60-T192 WeakPolarHBondContact CA-O 3.49Å; M60-T192 PolarHBondContact N-O 3.06Å; L189-T192 HydrophobicContact CB-CG2 4.38Å; T190-T192 PolarHBondContact O-N 3.24Å; T190-T192 PolarHBondContact O-OG1 3Å; T192-V209 HydrophobicContact CG2-CB 3.64Å; T192-V209 HydrophobicContact CG2-CG1 4.05Å; T192-V209 HydrophobicContact CG2-CG2 3.95Å; T192-K210 CarbonylContact C-O 3.52Å; T192-K210 WeakPolarHBondContact CA-O 3.34Å
193A95.7Very high88.9Confident27 Ų2751.9 Ų51.922%0.22329%0.285CS..EExtended strand (participates in β ladder)trans-95.5122.4178.600000110.5M60 V209 K210M60-A193 HydrophobicContact CB-CB 4.25Å; A193-V209 CarbonylContact O-C 3.05Å; A193-V209 VanDerWaalsContact O-CA 3.25Å; A193-V209 WeakPolarHBondContact O-CA 3.49Å; A193-K210 PolarHBondContact N-O 3.22Å; A193-K210 PolarHBondContact O-N 3.41Å
194A96.1Very high90.8Very high12 Ų1246 Ų4610%0.09926%0.257CS..EExtended strand (participates in β ladder)trans-74.3124.4163.700000109.3V35 V207 V208 V209 M267V35-A194 HydrophobicContact CG1-CB 3.51Å; V35-A194 HydrophobicContact CG2-CB 4.16Å; A194-V207 HydrophobicContact CB-CB 4.43Å; A194-V208 CarbonylContact C-O 3.56Å; A194-V208 WeakPolarHBondContact CA-O 3.21Å; A194-V209 HydrophobicContact CB-CG1 4.33Å; A194-M267 HydrophobicContact CB-CE 4.16Å; A194-M267 HydrophobicContact CB-SD 4.3Å
195T94.5Very high92.6Very high53 Ų5345.5 Ų45.533%0.32525%0.25SS..EExtended strand (participates in β ladder)trans-109.2-23.7-173.7590000113.3V208 K210T195-V208 PolarHBondContact N-O 3.38Å; T195-K210 HydrophobicContact CG2-CB 4.34Å; T195-K210 HydrophobicContact CG2-CD 4.07Å; T195-K210 HydrophobicContact CG2-CG 3.92Å
196S95Very high93.4Very high42 Ų4244.4 Ų44.429%0.29425%0.245SC..EExtended strand (participates in β ladder)trans-153.1153.6-179.3-49.20000111.3V207 V208 M267S196-V207 WeakPolarHBondContact O-CA 3.45Å; S196-V208 PolarHBondContact O-N 3Å; S196-M267 PolarHBondContact N-SD 3.23Å; S196-M267 VanDerWaalsContact N-SD 3.4Å
197L97.2Very high93.6Very high17 Ų1742.8 Ų42.89%0.08924%0.238CC..EExtended strand (participates in β ladder)trans-86.2139.5168-66.8167.4000109.2V204 V207 V225 L227 M267 V271 L465L197-V204 HydrophobicContact CD1-CG2 4.38Å; L197-V204 HydrophobicContact CD2-CG1 4.06Å; L197-V207 HydrophobicContact CD2-CG1 4.18Å; L197-V225 HydrophobicContact CD2-CB 4.29Å; L197-V225 HydrophobicContact CD2-CG1 3.81Å; L197-V225 HydrophobicContact CD2-CG2 4.46Å; L197-L227 HydrophobicContact CD2-CD2 4.39Å; L197-M267 HydrophobicContact CD1-CB 4.36Å; L197-M267 HydrophobicContact CG-CB 4.24Å; L197-V271 HydrophobicContact CB-CG1 3.97Å; L197-V271 HydrophobicContact CD1-CB 4.5Å; L197-V271 HydrophobicContact CD1-CG1 4.06Å; L197-V271 HydrophobicContact CD1-CG2 3.58Å; L197-L465 HydrophobicContact CD1-CD1 3.93Å; L197-L465 HydrophobicContact CD1-CD2 3.98Å; L197-L465 HydrophobicContact CD2-CD1 3.99Å
198V94.1Very high93.7Very high11 Ų1139.7 Ų39.77%0.06723%0.228CC..EExtended strand (participates in β ladder)trans-86.6132.7168.7164.20000108.2V204 A205 G206 V208 V219 F517V198-V204 CarbonylContact O-C 3.46Å; V198-V204 WeakPolarHBondContact O-CA 3.42Å; V198-A205 HydrophobicContact CG1-CB 4.2Å; V198-A205 PolarHBondContact O-N 3.06Å; V198-G206 PolarHBondContact N-O 3.39Å; V198-V208 HydrophobicContact CG2-CG2 4.08Å; V198-V219 HydrophobicContact CG2-CG1 3.79Å; V198-F517 HydrophobicContact CB-CE1 4.37Å; V198-F517 HydrophobicContact CG1-CD1 3.82Å; V198-F517 HydrophobicContact CG1-CE1 3.32Å; V198-F517 HydrophobicContact CG1-CZ 4.39Å; V198-F517 HydrophobicContact CG2-CD1 4.41Å; V198-F517 HydrophobicContact CG2-CE1 4.19Å
199T92.1Very high93.7Very high68 Ų6837.3 Ų37.342%0.41722%0.216SC..EExtended strand (participates in β ladder)trans-117.2152.6175.855.60000111.8G203 V204 V271T199-G203 CarbonylContact C-O 3.52Å; T199-G203 WeakPolarHBondContact CA-O 3.26Å; T199-V204 HydrophobicContact CG2-CG2 4.4Å; T199-V271 HydrophobicContact CG2-CB 4.33Å; T199-V271 HydrophobicContact CG2-CG1 3.61Å
200S89.4Confident93.6Very high59 Ų5940 Ų4041%0.41323%0.227SC..  trans-126-178.9168.9780000109.1E202 G203S200-E202 PolarHBondContact O-N 2.93Å; S200-E202 VanDerWaalsContact O-N 3.16Å; S200-E202 PolarHBondContact OG-N 3Å; S200-E202 VanDerWaalsContact OG-N 3.12Å; S200-G203 PolarHBondContact N-O 3.42Å; S200-G203 PolarHBondContact O-N 3.33Å
201K85.7Confident93.2Very high194 Ų19440 Ų4084%0.84322%0.224SC*.SBendtrans-59.2-23.9172-68.1-175.9179.7-179.50113.2
202E82.5Confident92.2Very high102 Ų10240.5 Ų40.548%0.47723%0.23SC..SBendtrans-92.4-23.3-176.2-63.8-165.7-160.200113.5S200 K463 L508S200-E202 PolarHBondContact O-N 2.93Å; S200-E202 VanDerWaalsContact O-N 3.16Å; S200-E202 PolarHBondContact OG-N 3Å; S200-E202 VanDerWaalsContact OG-N 3.12Å; E202-K463 HydrophobicContact CB-CD 4.35Å; E202-K463 VanDerWaalsContact O-CB 3.28Å; E202-K463 WeakPolarHBondContact O-CB 3.31Å; E202-K463 WeakPolarHBondContact O-CD 3.29Å; E202-K463 IonicContact OE2-NZ 2.68Å; E202-K463 PolarHBondContact OE2-NZ 3.06Å; E202-L508 WeakPolarHBondContact OE2-CD2 3.5Å
203G92Very high91.4Very high16 Ų1646.1 Ų46.117%0.16526%0.259CS..SBendtrans152-153.6-174.900000112.9T199 S200 K463T199-G203 CarbonylContact C-O 3.52Å; T199-G203 WeakPolarHBondContact CA-O 3.26Å; S200-G203 PolarHBondContact N-O 3.42Å; S200-G203 PolarHBondContact O-N 3.33Å; G203-K463 WeakPolarHBondContact CA-O 3.33Å
204V95.2Very high90.2Very high7 Ų747 Ų474%0.04227%0.272CS..EExtended strand (participates in β ladder)trans-75.1136.8173.2171.60000109.8L197 V198 T199 V225 I462 K463 L465L197-V204 HydrophobicContact CD1-CG2 4.38Å; L197-V204 HydrophobicContact CD2-CG1 4.06Å; V198-V204 CarbonylContact O-C 3.46Å; V198-V204 WeakPolarHBondContact O-CA 3.42Å; T199-V204 HydrophobicContact CG2-CG2 4.4Å; V204-V225 HydrophobicContact CG1-CB 3.98Å; V204-V225 HydrophobicContact CG1-CG2 3.64Å; V204-I462 HydrophobicContact CG2-CG2 4.07Å; V204-K463 PolarHBondContact N-O 3.34Å; V204-L465 HydrophobicContact CB-CB 4.18Å; V204-L465 HydrophobicContact CG1-CD1 4.44Å; V204-L465 HydrophobicContact CG2-CB 3.88Å; V204-L465 HydrophobicContact CG2-CD1 4.31Å; V204-L465 HydrophobicContact CG2-CD2 4.19Å; V204-L465 HydrophobicContact CG2-CG 4.34Å
205A94.3Very high89.3Confident26 Ų2652.1 Ų52.122%0.21530%0.302CS..EExtended strand (participates in β ladder)trans-13422.9-174.200000113.4V198 P221 A222V198-A205 HydrophobicContact CG1-CB 4.2Å; V198-A205 PolarHBondContact O-N 3.06Å; A205-P221 WeakPolarHBondContact O-CA 3.34Å; A205-A222 CarbonylContact C-O 3.43Å; A205-A222 VanDerWaalsContact CA-O 3.31Å; A205-A222 WeakPolarHBondContact CA-O 3.22Å; A205-A222 PolarHBondContact O-N 3.42Å; A205-A222 VanDerWaalsContact O-N 3.09Å
206G94.6Very high88.6Confident0 Ų054.5 Ų54.50%031%0.309CS..EExtended strand (participates in β ladder)trans139.5-161.8176.800000113.7V198 I220V198-G206 PolarHBondContact N-O 3.39Å; G206-I220 VanDerWaalsContact CA-O 3.25Å; G206-I220 WeakPolarHBondContact CA-O 3.12Å
207V96.1Very high88.3Confident0 Ų055.5 Ų55.50%031%0.313CS..EExtended strand (participates in β ladder)trans-136.1151.4-178.1-65.50000112V33 V35 I58 A194 S196 L197 V209 V219 I220 V225V33-V207 HydrophobicContact CG1-CG1 4.22Å; V33-V207 HydrophobicContact CG1-CG2 3.83Å; V35-V207 HydrophobicContact CG2-CG1 4.07Å; I58-V207 HydrophobicContact CD1-CG2 3.76Å; A194-V207 HydrophobicContact CB-CB 4.43Å; S196-V207 WeakPolarHBondContact O-CA 3.45Å; L197-V207 HydrophobicContact CD2-CG1 4.18Å; V207-V209 HydrophobicContact CG2-CG1 3.8Å; V207-V219 WeakPolarHBondContact O-CA 3.42Å; V207-I220 HydrophobicContact CG2-CB 4.02Å; V207-I220 PolarHBondContact N-O 2.92Å; V207-I220 PolarHBondContact O-N 3.37Å; V207-V225 HydrophobicContact CG1-CG1 3.83Å; V207-V225 HydrophobicContact CG1-CG2 3.95Å
208V95.2Very high88Confident14 Ų1458.5 Ų58.59%0.08532%0.324CS..EExtended strand (participates in β ladder)trans-91.2129.2160.5-1760000107.8A194 T195 S196 V198 T217 V219A194-V208 CarbonylContact C-O 3.56Å; A194-V208 WeakPolarHBondContact CA-O 3.21Å; T195-V208 PolarHBondContact N-O 3.38Å; S196-V208 PolarHBondContact O-N 3Å; V198-V208 HydrophobicContact CG2-CG2 4.08Å; V208-T217 HydrophobicContact CG1-CG2 3.62Å; V208-V219 HydrophobicContact CG2-CG2 4.38Å
209V95.1Very high88Confident2 Ų260.6 Ų60.61%0.01234%0.336CS..EExtended strand (participates in β ladder)trans-119.5151176.3-57.80000111.7I58 T192 A193 A194 V207 T217 R218 I220I58-V209 HydrophobicContact CD1-CG1 3.69Å; T192-V209 HydrophobicContact CG2-CB 3.64Å; T192-V209 HydrophobicContact CG2-CG1 4.05Å; T192-V209 HydrophobicContact CG2-CG2 3.95Å; A193-V209 CarbonylContact O-C 3.05Å; A193-V209 VanDerWaalsContact O-CA 3.25Å; A193-V209 WeakPolarHBondContact O-CA 3.49Å; A194-V209 HydrophobicContact CB-CG1 4.33Å; V207-V209 HydrophobicContact CG2-CG1 3.8Å; V209-T217 WeakPolarHBondContact O-CA 3.43Å; V209-R218 HydrophobicContact CG2-CG 3.47Å; V209-R218 VanDerWaalsContact CG2-CG 3.47Å; V209-R218 PolarHBondContact N-O 3.16Å; V209-R218 PolarHBondContact O-N 3.18Å; V209-I220 HydrophobicContact CG1-CD1 3.92Å; V209-I220 HydrophobicContact CG1-CG1 4.43Å; V209-I220 HydrophobicContact CG2-CD1 3.88Å; V209-I220 HydrophobicContact CG2-CG1 4.11Å
210K92.8Very high88Confident73 Ų7358.1 Ų58.132%0.31732%0.32SS..EExtended strand (participates in β ladder)trans-124.3143.1168.5-60.3-168179-177.10110.2T192 A193 T195 E216 T217T192-K210 CarbonylContact C-O 3.52Å; T192-K210 WeakPolarHBondContact CA-O 3.34Å; A193-K210 PolarHBondContact N-O 3.22Å; A193-K210 PolarHBondContact O-N 3.41Å; T195-K210 HydrophobicContact CG2-CB 4.34Å; T195-K210 HydrophobicContact CG2-CD 4.07Å; T195-K210 HydrophobicContact CG2-CG 3.92Å; K210-E216 VanDerWaalsContact CA-O 3.23Å; K210-E216 WeakPolarHBondContact CA-O 3.44Å; K210-T217 WeakPolarHBondContact CE-OG1 3.07Å; K210-T217 HydrophobicContact CG-CG2 4.13Å; K210-T217 WeakPolarHBondContact CG-OG1 3.33Å
211D87.9Confident88.2Confident46 Ų4657.5 Ų57.525%0.24632%0.315CS..EExtended strand (participates in β ladder)trans-60.3149.2160.2179.360.3000109.2N191 N213 G214 E216N191-D211 VanDerWaalsContact O-OD1 3.06Å; D211-N213 PolarHBondContact O-N 3.48Å; D211-N213 VanDerWaalsContact O-N 3.16Å; D211-N213 VanDerWaalsContact OD2-CB 3.27Å; D211-N213 WeakPolarHBondContact OD2-CB 3.37Å; D211-N213 PolarHBondContact OD2-N 2.86Å; D211-N213 VanDerWaalsContact OD2-N 3.09Å; D211-N213 PolarHBondContact OD2-ND2 3.44Å; D211-G214 WeakPolarHBondContact O-CA 3.3Å; D211-G214 PolarHBondContact O-N 3.42Å; D211-E216 PolarHBondContact N-O 3.03Å; D211-E216 VanDerWaalsContact N-O 3.15Å
212V75.9Confident88.6Confident71 Ų7148.5 Ų48.543%0.4328%0.277SS..THydrogen-bonded Turntrans-60.9-23.2-179.4-72.40000113.5M60 N191 G214M60-V212 WeakPolarHBondContact O-CG1 3.3Å; N191-V212 HydrophobicContact CB-CG1 4.35Å; N191-V212 HydrophobicContact CB-CG2 3.73Å; N191-V212 WeakPolarHBondContact O-CG1 3.4Å; N191-V212 PolarHBondContact O-N 2.96Å; V212-G214 PolarHBondContact O-N 3.17Å
213N77.2Confident89.1Confident128 Ų12844.7 Ų44.768%0.68426%0.26SS*.THydrogen-bonded Turntrans-78-4.7172.8-55.7-60.2000112.8D211 T215D211-N213 PolarHBondContact O-N 3.48Å; D211-N213 VanDerWaalsContact O-N 3.16Å; D211-N213 VanDerWaalsContact OD2-CB 3.27Å; D211-N213 WeakPolarHBondContact OD2-CB 3.37Å; D211-N213 PolarHBondContact OD2-N 2.86Å; D211-N213 VanDerWaalsContact OD2-N 3.09Å; D211-N213 PolarHBondContact OD2-ND2 3.44Å; N213-T215 HydrophobicContact CB-CG2 4.05Å; N213-T215 PolarHBondContact O-N 2.97Å
214G72.2Confident89.4Confident47 Ų4744 Ų4449%0.48525%0.252SS..SBendtrans72.36.3-179.700000114.8D211 V212D211-G214 WeakPolarHBondContact O-CA 3.3Å; D211-G214 PolarHBondContact O-N 3.42Å; V212-G214 PolarHBondContact O-N 3.17Å
215T76.6Confident89.5Confident119 Ų11943.7 Ų43.773%0.7325%0.25SS*.  trans-79-26.9-171.151.10000114N213N213-T215 HydrophobicContact CB-CG2 4.05Å; N213-T215 PolarHBondContact O-N 2.97Å
216E80Confident89.8Confident102 Ų10242.4 Ų42.448%0.47724%0.24SC..  trans-127129.1-179.6-169-175146.500109.2K210 D211 R218K210-E216 VanDerWaalsContact CA-O 3.23Å; K210-E216 WeakPolarHBondContact CA-O 3.44Å; D211-E216 PolarHBondContact N-O 3.03Å; D211-E216 VanDerWaalsContact N-O 3.15Å; E216-R218 IonicContact OE1-CZ 3.91Å; E216-R218 IonicContact OE1-NH1 2.96Å; E216-R218 PolarHBondContact OE1-NH1 3Å
217T88.1Confident90Very high63 Ų6342.4 Ų42.439%0.38724%0.24SC..EExtended strand (participates in β ladder)trans-118.3128.2170-58.20000108.2V208 V209 K210V208-T217 HydrophobicContact CG1-CG2 3.62Å; V209-T217 WeakPolarHBondContact O-CA 3.43Å; K210-T217 WeakPolarHBondContact CE-OG1 3.07Å; K210-T217 HydrophobicContact CG-CG2 4.13Å; K210-T217 WeakPolarHBondContact CG-OG1 3.33Å
218R91.7Very high90.1Very high81 Ų8142.8 Ų42.831%0.30624%0.242SC..EExtended strand (participates in β ladder)trans-142.6159.7176.667.9179.4-179.5-135.61112.4V209 E216V209-R218 HydrophobicContact CG2-CG 3.47Å; V209-R218 VanDerWaalsContact CG2-CG 3.47Å; V209-R218 PolarHBondContact N-O 3.16Å; V209-R218 PolarHBondContact O-N 3.18Å; E216-R218 IonicContact OE1-CZ 3.91Å; E216-R218 IonicContact OE1-NH1 2.96Å; E216-R218 PolarHBondContact OE1-NH1 3Å
219V92.7Very high90.3Very high54 Ų5442.9 Ų42.933%0.32724%0.243SC..EExtended strand (participates in β ladder)trans-94.5134.4172.3178.30000108.9V198 V207 V208 F517V198-V219 HydrophobicContact CG2-CG1 3.79Å; V207-V219 WeakPolarHBondContact O-CA 3.42Å; V208-V219 HydrophobicContact CG2-CG2 4.38Å; V219-F517 HydrophobicContact CG1-CE1 4.34Å
220I93.2Very high90.4Very high16 Ų1643.6 Ų43.68%0.08225%0.251CS..EExtended strand (participates in β ladder)trans-111.3100.2166.9-57.1179.4000106.7P30 V33 T56 I58 L189 G206 V207 V209P30-I220 HydrophobicContact CG-CG2 3.8Å; V33-I220 HydrophobicContact CG2-CG2 3.74Å; T56-I220 HydrophobicContact CG2-CD1 4.5Å; I58-I220 HydrophobicContact CD1-CD1 4.15Å; L189-I220 HydrophobicContact CD1-CD1 3.67Å; G206-I220 VanDerWaalsContact CA-O 3.25Å; G206-I220 WeakPolarHBondContact CA-O 3.12Å; V207-I220 HydrophobicContact CG2-CB 4.02Å; V207-I220 PolarHBondContact N-O 2.92Å; V207-I220 PolarHBondContact O-N 3.37Å; V209-I220 HydrophobicContact CG1-CD1 3.92Å; V209-I220 HydrophobicContact CG1-CG1 4.43Å; V209-I220 HydrophobicContact CG2-CD1 3.88Å; V209-I220 HydrophobicContact CG2-CG1 4.11Å
221P93.6Very high90.7Very high46 Ų4640.1 Ų40.130%0.29924%0.235SC..EExtended strand (participates in β ladder)trans-66.8145.7174.327-30.1000110.1T29 A205T29-P221 HydrophobicContact CG2-CB 4.3Å; T29-P221 HydrophobicContact CG2-CG 3.97Å; T29-P221 WeakPolarHBondContact CG2-O 3.33Å; A205-P221 WeakPolarHBondContact O-CA 3.34Å
222A93.7Very high91.1Very high6 Ų637.9 Ų37.95%0.0522%0.224CC..  trans-158153175.300000111P30 V33 A205 A224P30-A222 HydrophobicContact CG-CB 4.34Å; P30-A222 VanDerWaalsContact O-CA 3.31Å; P30-A222 WeakPolarHBondContact O-CA 3.42Å; V33-A222 HydrophobicContact CB-CB 4.11Å; V33-A222 HydrophobicContact CG2-CB 3.58Å; A205-A222 CarbonylContact C-O 3.43Å; A205-A222 VanDerWaalsContact CA-O 3.31Å; A205-A222 WeakPolarHBondContact CA-O 3.22Å; A205-A222 PolarHBondContact O-N 3.42Å; A205-A222 VanDerWaalsContact O-N 3.09Å; A222-A224 VanDerWaalsContact C-N 3.31Å
223D93.5Very high92.2Very high22 Ų2234.5 Ų34.512%0.11820%0.203CC..SBendtrans-72.9-28.2176.5-63-39000111.8D31 L508D31-D223 WeakPolarHBondContact O-CB 3.5Å; D31-D223 PolarHBondContact O-N 3Å; D223-L508 VanDerWaalsContact OD1-CB 3.28Å; D223-L508 WeakPolarHBondContact OD1-CB 3.12Å
224A97.2Very high93.1Very high1 Ų129 Ų291%0.00817%0.173CC..EExtended strand (participates in β ladder)trans-143.2149.5173.600000113D31 V32 V33 A222 G464 Y466 A500D31-A224 PolarHBondContact O-N 3.28Å; V32-A224 WeakPolarHBondContact CA-O 3.42Å; V33-A224 PolarHBondContact N-O 3.46Å; A222-A224 VanDerWaalsContact C-N 3.31Å; A224-G464 CarbonylContact C-O 3.59Å; A224-G464 WeakPolarHBondContact CA-O 3.46Å; A224-Y466 HydrophobicContact CB-CD2 4.34Å; A224-Y466 HydrophobicContact CB-CE2 4.05Å; A224-A500 HydrophobicContact CB-CB 3.85Å
225V98.6Very high94.2Very high0 Ų027.2 Ų27.20%015%0.153CC..EExtended strand (participates in β ladder)trans-119.7130.1172.7179.90000109.7V33 V35 L197 V204 V207 L227 G464 L465 Y466V33-V225 HydrophobicContact CB-CG2 4.47Å; V33-V225 CarbonylContact O-C 3.59Å; V33-V225 WeakPolarHBondContact O-CA 3.26Å; V35-V225 HydrophobicContact CG2-CG1 4.05Å; L197-V225 HydrophobicContact CD2-CB 4.29Å; L197-V225 HydrophobicContact CD2-CG1 3.81Å; L197-V225 HydrophobicContact CD2-CG2 4.46Å; V204-V225 HydrophobicContact CG1-CB 3.98Å; V204-V225 HydrophobicContact CG1-CG2 3.64Å; V207-V225 HydrophobicContact CG1-CG1 3.83Å; V207-V225 HydrophobicContact CG1-CG2 3.95Å; V225-L227 HydrophobicContact CG1-CD2 4.21Å; V225-G464 PolarHBondContact N-O 3.13Å; V225-L465 HydrophobicContact CB-CD1 4.25Å; V225-L465 HydrophobicContact CG1-CD1 4.38Å; V225-Y466 PolarHBondContact O-N 2.84Å
226V98.9Very high94.8Very high0 Ų025.2 Ų25.20%014%0.135CC..EExtended strand (participates in β ladder)trans-110113.1172.3-166.90000109.3V32 V33 V34 V35 A44 T228 Y466 A496 A500V32-V226 HydrophobicContact CG1-CG2 3.81Å; V33-V226 PolarHBondContact O-N 3.4Å; V34-V226 WeakPolarHBondContact CA-O 3Å; V34-V226 HydrophobicContact CG1-CB 4.49Å; V34-V226 HydrophobicContact CG2-CB 4.27Å; V34-V226 HydrophobicContact CG2-CG2 4.39Å; V35-V226 PolarHBondContact N-O 3.13Å; A44-V226 HydrophobicContact CB-CG1 4.12Å; V226-T228 HydrophobicContact CG1-CG2 4.05Å; V226-Y466 WeakPolarHBondContact CA-O 3.18Å; V226-A496 HydrophobicContact CG1-CB 3.7Å; V226-A500 HydrophobicContact CG2-CB 3.62Å
227L98.9Very high95.4Very high0 Ų023.4 Ų23.40%013%0.131CC..EExtended strand (participates in β ladder)trans-82.2123.6174-63.6177.6000110.2V35 L197 V225 M267 A268 I446 L465 Y466 A467 A468 V471V35-L227 HydrophobicContact CB-CD2 4.06Å; V35-L227 HydrophobicContact CG2-CD2 4.1Å; L197-L227 HydrophobicContact CD2-CD2 4.39Å; V225-L227 HydrophobicContact CG1-CD2 4.21Å; L227-M267 HydrophobicContact CD2-CE 3.92Å; L227-A268 HydrophobicContact CD1-CB 3.82Å; L227-I446 HydrophobicContact CD1-CD1 3.83Å; L227-L465 HydrophobicContact CD1-CD1 4.03Å; L227-L465 HydrophobicContact CG-CD1 4.11Å; L227-Y466 PolarHBondContact N-O 3.18Å; L227-A467 HydrophobicContact CB-CB 4.34Å; L227-A467 CarbonylContact O-C 3.6Å; L227-A467 VanDerWaalsContact O-CA 3.29Å; L227-A467 WeakPolarHBondContact O-CA 3.21Å; L227-A468 PolarHBondContact O-N 3.48Å; L227-V471 HydrophobicContact CB-CG1 4.42Å; L227-V471 VanDerWaalsContact O-CG1 3.27Å; L227-V471 WeakPolarHBondContact O-CG1 3.24Å
228T98.9Very high95.6Very high7 Ų728.4 Ų28.44%0.04315%0.15CC..  trans-139.934.4178.650.70000111.2V34 V35 G36 A40 G41 V226 G230 A468V34-T228 HydrophobicContact CG1-CG2 4.48Å; V34-T228 WeakPolarHBondContact CG1-OG1 3.15Å; V35-T228 CarbonylContact O-C 2.96Å; V35-T228 WeakPolarHBondContact O-CA 3.28Å; V35-T228 PolarHBondContact O-N 3.19Å; V35-T228 PolarHBondContact O-OG1 3.47Å; G36-T228 PolarHBondContact O-OG1 3.16Å; A40-T228 HydrophobicContact CB-CG2 3.92Å; G41-T228 WeakPolarHBondContact CA-OG1 3.32Å; V226-T228 HydrophobicContact CG1-CG2 4.05Å; T228-G230 PolarHBondContact O-N 3.24Å; T228-G230 VanDerWaalsContact O-N 3.16Å; T228-A468 HydrophobicContact CG2-CB 3.96Å
229T98.7Very high95.6Very high16 Ų1629.3 Ų29.310%0.09816%0.161CC..  trans-74.2-3.6-170.258.30000114.7V35 G264 V471V35-T229 HydrophobicContact CB-CG2 4.29Å; V35-T229 HydrophobicContact CG1-CG2 3.72Å; V35-T229 WeakPolarHBondContact O-CG2 3.42Å; V35-T229 PolarHBondContact O-N 3.25Å; T229-G264 VanDerWaalsContact OG1-CA 3.23Å; T229-G264 WeakPolarHBondContact OG1-CA 3.3Å; T229-G264 PolarHBondContact OG1-N 2.97Å; T229-G264 VanDerWaalsContact OG1-N 3.1Å; T229-V471 VanDerWaalsContact OG1-CG2 3.3Å; T229-V471 WeakPolarHBondContact OG1-CG2 3.47Å
230G98.3Very high95.8Very high17 Ų1726.8 Ų26.818%0.17515%0.145CC..  trans71.3-173.2-167.700000113T228T228-G230 PolarHBondContact O-N 3.24Å; T228-G230 VanDerWaalsContact O-N 3.16Å
231G98.2Very high96Very high0 Ų026.1 Ų26.10%014%0.142CC..  trans-84.7-157.4-173.900000114.8A260 T261 G262G231-A260 CarbonylContact O-C 3.57Å; G231-A260 WeakPolarHBondContact O-CA 3.46Å; G231-T261 PolarHBondContact O-N 3.34Å; G231-G262 WeakPolarHBondContact O-CA 3.41Å; G231-G262 PolarHBondContact O-N 2.74Å
232Y98Very high96.2Very high0 Ų024.1 Ų24.10%013%0.129CC..SBendtrans-124.923.7-173.856.7-82.5000112.9N234 L241 I242 A260 I265 M278 R280 L281 S442 G444Y232-N234 VanDerWaalsContact C-N 3.26Å; Y232-N234 PolarHBondContact O-N 3.11Å; Y232-L241 HydrophobicContact CD1-CD1 4.13Å; Y232-L241 HydrophobicContact CD2-CB 3.54Å; Y232-L241 HydrophobicContact CD2-CD1 4.49Å; Y232-L241 HydrophobicContact CE2-CB 4.18Å; Y232-L241 HydrophobicContact CG-CB 3.79Å; Y232-L241 HydrophobicContact CG-CD1 3.91Å; Y232-L241 HydrophobicContact CG-CG 4.5Å; Y232-I242 HydrophobicContact CD2-CG1 4.07Å; Y232-I242 WeakPolarHBondContact O-CD1 3.25Å; Y232-I242 WeakPolarHBondContact O-CG1 3.34Å; Y232-A260 CarbonylContact C-O 3.46Å; Y232-A260 WeakPolarHBondContact CA-O 3.5Å; Y232-I265 HydrophobicContact CD1-CD1 3.49Å; Y232-I265 VanDerWaalsContact CD1-CD1 3.49Å; Y232-I265 HydrophobicContact CE1-CD1 3.93Å; Y232-M278 HydrophobicContact CD1-CE 4.12Å; Y232-M278 HydrophobicContact CE1-CE 3.56Å; Y232-M278 HydrophobicContact CE1-SD 4.38Å; Y232-M278 HydrophobicContact CE2-CE 4.36Å; Y232-M278 PolarHBondContact OH-O 3.28Å; Y232-R280 PolarHBondContact OH-O 2.97Å; Y232-L281 HydrophobicContact CD2-CD2 4.19Å; Y232-L281 HydrophobicContact CE2-CD1 3.93Å; Y232-L281 HydrophobicContact CE2-CD2 3.91Å; Y232-L281 HydrophobicContact CE2-CG 4.01Å; Y232-S442 VanDerWaalsContact CD1-OG 3.31Å; Y232-S442 WeakPolarHBondContact CD1-OG 3.47Å; Y232-S442 WeakPolarHBondContact CE1-OG 3.39Å; Y232-S442 PolarHBondContact N-OG 2.88Å; Y232-G444 WeakPolarHBondContact CE1-O 3.36Å
233S97.2Very high96.4Very high0 Ų027.2 Ų27.20%014%0.143CC..THydrogen-bonded Turntrans-78.54.9-172.7-70.70000115.1T254 N256 A260 S442S233-T254 WeakPolarHBondContact O-CB 3.31Å; S233-T254 PolarHBondContact O-OG1 3.23Å; S233-N256 VanDerWaalsContact CB-ND2 3.31Å; S233-N256 WeakPolarHBondContact CB-ND2 3.36Å; S233-A260 PolarHBondContact N-O 3.44Å; S233-S442 PolarHBondContact N-OG 2.67Å; S233-S442 PolarHBondContact OG-N 3.2Å; S233-S442 PolarHBondContact OG-OG 3.38Å
234N97.1Very high96.5Very high11 Ų1131.2 Ų31.26%0.05916%0.161CC..THydrogen-bonded Turntrans-14550.6174.9-165.31.4000111.7Y232 H236 T254 N256 G257 A260Y232-N234 VanDerWaalsContact C-N 3.26Å; Y232-N234 PolarHBondContact O-N 3.11Å; N234-H236 PolarHBondContact OD1-CD2 3.45Å; N234-H236 VanDerWaalsContact OD1-CD2 3.28Å; N234-H236 PolarHBondContact OD1-NE2 3.39Å; N234-T254 HydrophobicContact CB-CG2 3.9Å; N234-T254 VanDerWaalsContact CG-CG2 3.5Å; N234-N256 HydrophobicContact CB-CB 3.92Å; N234-N256 PolarHBondContact ND2-O 3.11Å; N234-G257 VanDerWaalsContact CB-O 3.27Å; N234-G257 WeakPolarHBondContact CB-O 3.44Å; N234-G257 VanDerWaalsContact ND2-C 3.27Å; N234-G257 PolarHBondContact ND2-O 3.34Å; N234-A260 CarbonylContact C-O 3.53Å; N234-A260 HydrophobicContact CB-CB 4.21Å; N234-A260 PolarHBondContact N-O 3.15Å
235D95.3Very high96.6Very high11 Ų1134.9 Ų34.96%0.05918%0.175CC..  trans-115.7106.8172.9-166-3.9000110.3T237 S240 K266D235-T237 PolarHBondContact OD1-N 3.32Å; D235-T237 PolarHBondContact OD1-OG1 3.45Å; D235-T237 VanDerWaalsContact OD1-OG1 3.12Å; D235-S240 VanDerWaalsContact O-CB 3.24Å; D235-S240 WeakPolarHBondContact O-CB 3.34Å; D235-S240 PolarHBondContact O-OG 3.21Å; D235-S240 WeakPolarHBondContact OD2-CB 3.24Å; D235-K266 IonicContact OD2-NZ 2.82Å; D235-K266 PolarHBondContact OD2-NZ 2.95Å
236H89.2Confident96.4Very high77 Ų7734.9 Ų34.936%0.35618%0.176SC..  trans-100.78.7-174.7-62.4-63.4000113.3N234N234-H236 PolarHBondContact OD1-CD2 3.45Å; N234-H236 VanDerWaalsContact OD1-CD2 3.28Å; N234-H236 PolarHBondContact OD1-NE2 3.39Å
237T92.6Very high96.3Very high63 Ų6337.9 Ų37.939%0.38720%0.196SC..SBendtrans-73.2161.2174.369.20000111D235 D239 S240 M243D235-T237 PolarHBondContact OD1-N 3.32Å; D235-T237 PolarHBondContact OD1-OG1 3.45Å; D235-T237 VanDerWaalsContact OD1-OG1 3.12Å; T237-D239 VanDerWaalsContact C-N 3.26Å; T237-D239 WeakPolarHBondContact CB-OD1 3.5Å; T237-D239 PolarHBondContact O-N 2.79Å; T237-D239 PolarHBondContact OG1-OD1 3.27Å; T237-S240 VanDerWaalsContact O-CB 3.31Å; T237-S240 WeakPolarHBondContact O-CB 3.38Å; T237-S240 PolarHBondContact O-N 2.96Å; T237-S240 PolarHBondContact O-OG 2.86Å; T237-S240 PolarHBondContact OG1-N 3.07Å; T237-M243 WeakPolarHBondContact O-CG 3.36Å
238H92Very high96.1Very high169 Ų16945.5 Ų45.578%0.78223%0.225SC*.THydrogen-bonded Turntrans-69.1-26.1-178.564.7-85.3000112.8M243H238-M243 WeakPolarHBondContact O-CB 3.36Å
239D92.2Very high95.9Very high99 Ų9945.2 Ų45.253%0.52922%0.223SC..THydrogen-bonded Turntrans-95.812.9178.469.3-37.2000112.9T237T237-D239 VanDerWaalsContact C-N 3.26Å; T237-D239 WeakPolarHBondContact CB-OD1 3.5Å; T237-D239 PolarHBondContact O-N 2.79Å; T237-D239 PolarHBondContact OG1-OD1 3.27Å
240S96.9Very high95.6Very high1 Ų149.1 Ų49.11%0.00724%0.239CC..SBendtrans-68.4159-178.582.60000113.3D235 T237 I242 M243 Q244D235-S240 VanDerWaalsContact O-CB 3.24Å; D235-S240 WeakPolarHBondContact O-CB 3.34Å; D235-S240 PolarHBondContact O-OG 3.21Å; D235-S240 WeakPolarHBondContact OD2-CB 3.24Å; T237-S240 VanDerWaalsContact O-CB 3.31Å; T237-S240 WeakPolarHBondContact O-CB 3.38Å; T237-S240 PolarHBondContact O-N 2.96Å; T237-S240 PolarHBondContact O-OG 2.86Å; T237-S240 PolarHBondContact OG1-N 3.07Å; S240-I242 PolarHBondContact O-N 2.77Å; S240-I242 PolarHBondContact OG-N 3.35Å; S240-M243 PolarHBondContact O-N 3.49Å; S240-M243 PolarHBondContact OG-N 2.96Å; S240-M243 VanDerWaalsContact OG-N 3.1Å; S240-Q244 PolarHBondContact O-N 3.1Å
241L97.6Very high95.2Very high3 Ų353.6 Ų53.62%0.01626%0.259CS..Hα-helixtrans-66.1-27.4174.1-63.1176000112Y232 Q244 Y245 I265 K266 M278Y232-L241 HydrophobicContact CD1-CD1 4.13Å; Y232-L241 HydrophobicContact CD2-CB 3.54Å; Y232-L241 HydrophobicContact CD2-CD1 4.49Å; Y232-L241 HydrophobicContact CE2-CB 4.18Å; Y232-L241 HydrophobicContact CG-CB 3.79Å; Y232-L241 HydrophobicContact CG-CD1 3.91Å; Y232-L241 HydrophobicContact CG-CG 4.5Å; L241-Q244 PolarHBondContact O-N 3.35Å; L241-Y245 HydrophobicContact CB-CD2 4.39Å; L241-Y245 HydrophobicContact CD2-CD2 4.27Å; L241-Y245 HydrophobicContact CD2-CE2 3.84Å; L241-Y245 WeakPolarHBondContact O-CD2 3.49Å; L241-Y245 PolarHBondContact O-N 3.04Å; L241-I265 HydrophobicContact CD1-CB 4Å; L241-I265 HydrophobicContact CD1-CD1 4.4Å; L241-I265 HydrophobicContact CD1-CG2 3.69Å; L241-K266 HydrophobicContact CD1-CG 4.31Å; L241-K266 HydrophobicContact CD2-CG 4.45Å; L241-K266 HydrophobicContact CG-CG 4.44Å; L241-M278 HydrophobicContact CD1-CE 4.02Å
242I97.4Very high95.1Very high4 Ų456.4 Ų56.42%0.02127%0.271CS..Hα-helixtrans-64.3-48.3171.4-64.5177.5000109.5Y232 S240 Q244 Y245 A246 S247 L249 L281 I439Y232-I242 HydrophobicContact CD2-CG1 4.07Å; Y232-I242 WeakPolarHBondContact O-CD1 3.25Å; Y232-I242 WeakPolarHBondContact O-CG1 3.34Å; S240-I242 PolarHBondContact O-N 2.77Å; S240-I242 PolarHBondContact OG-N 3.35Å; I242-Q244 VanDerWaalsContact C-N 3.29Å; I242-Q244 PolarHBondContact O-N 2.84Å; I242-Y245 PolarHBondContact O-N 3.39Å; I242-A246 CarbonylContact O-C 3.49Å; I242-A246 VanDerWaalsContact O-CA 3.31Å; I242-A246 WeakPolarHBondContact O-CA 3.48Å; I242-A246 PolarHBondContact O-N 2.88Å; I242-S247 PolarHBondContact O-N 2.96Å; I242-L249 HydrophobicContact CG2-CB 4.37Å; I242-L281 HydrophobicContact CD1-CD2 4.24Å; I242-L281 HydrophobicContact CG1-CD2 4.03Å; I242-I439 HydrophobicContact CD1-CD1 4.28Å
243M97Very high95.1Very high70 Ų7056.8 Ų56.835%0.34527%0.274SS..Hα-helixtrans-63.2-36.4178.2-70.2-55.5-60.100112.3T237 H238 S240 K250T237-M243 WeakPolarHBondContact O-CG 3.36Å; H238-M243 WeakPolarHBondContact O-CB 3.36Å; S240-M243 PolarHBondContact O-N 3.49Å; S240-M243 PolarHBondContact OG-N 2.96Å; S240-M243 VanDerWaalsContact OG-N 3.1Å; M243-K250 HydrophobicContact CE-CD 4.19Å; M243-K250 HydrophobicContact SD-CB 3.59Å; M243-K250 VanDerWaalsContact SD-CB 3.59Å; M243-K250 HydrophobicContact SD-CD 4.02Å; M243-K250 HydrophobicContact SD-CG 4.44Å
244Q97.4Very high95.1Very high106 Ų10656.8 Ų56.850%0.49527%0.274SS..Hα-helixtrans-71.2-40.8179.9-173.6171.323.300113.6S240 L241 I242S240-Q244 PolarHBondContact O-N 3.1Å; L241-Q244 PolarHBondContact O-N 3.35Å; I242-Q244 VanDerWaalsContact C-N 3.29Å; I242-Q244 PolarHBondContact O-N 2.84Å
245Y97.6Very high95.2Very high78 Ų7857.1 Ų57.131%0.30628%0.276SS..Hα-helixtrans-117.9-19.5-168.2-64.2-79.4000114.9L241 I242 M278 N279L241-Y245 HydrophobicContact CB-CD2 4.39Å; L241-Y245 HydrophobicContact CD2-CD2 4.27Å; L241-Y245 HydrophobicContact CD2-CE2 3.84Å; L241-Y245 WeakPolarHBondContact O-CD2 3.49Å; L241-Y245 PolarHBondContact O-N 3.04Å; I242-Y245 PolarHBondContact O-N 3.39Å; Y245-M278 WeakPolarHBondContact CB-O 3.31Å; Y245-M278 HydrophobicContact CD1-CB 3.54Å; Y245-M278 HydrophobicContact CD2-CB 3.83Å; Y245-M278 HydrophobicContact CD2-CE 4.26Å; Y245-M278 HydrophobicContact CE1-CB 3.85Å; Y245-M278 HydrophobicContact CE1-CG 4.35Å; Y245-M278 HydrophobicContact CE2-CB 4.13Å; Y245-M278 HydrophobicContact CE2-CE 4.29Å; Y245-M278 HydrophobicContact CE2-CG 4.42Å; Y245-M278 HydrophobicContact CG-CB 3.53Å; Y245-N279 WeakPolarHBondContact O-CA 3.11Å; Y245-N279 WeakPolarHBondContact O-CB 3.41Å
246A96.1Very high95.3Very high1 Ų156.8 Ų56.81%0.00827%0.274CS..  trans-147.745-173.600000112I242 W248 L249 L281I242-A246 CarbonylContact O-C 3.49Å; I242-A246 VanDerWaalsContact O-CA 3.31Å; I242-A246 WeakPolarHBondContact O-CA 3.48Å; I242-A246 PolarHBondContact O-N 2.88Å; A246-W248 PolarHBondContact O-N 3.21Å; A246-L249 HydrophobicContact CB-CD1 4.17Å; A246-L249 WeakPolarHBondContact O-CB 3.36Å; A246-L249 PolarHBondContact O-N 2.81Å; A246-L281 HydrophobicContact CB-CD1 3.41Å; A246-L281 VanDerWaalsContact CB-CD1 3.41Å
247S95.9Very high95.6Very high62 Ų6253.1 Ų53.143%0.43426%0.258SS..G310 helixtrans-57.5-23.4-173.958.40000114.3I242 L249 K250I242-S247 PolarHBondContact O-N 2.96Å; S247-L249 PolarHBondContact O-N 3.16Å; S247-K250 VanDerWaalsContact O-CB 3.26Å; S247-K250 WeakPolarHBondContact O-CB 3.06Å; S247-K250 VanDerWaalsContact O-CG 3.22Å; S247-K250 WeakPolarHBondContact O-CG 3.39Å; S247-K250 PolarHBondContact O-N 3.42Å; S247-K250 VanDerWaalsContact O-N 3.08Å
248W94.4Very high95.8Very high161 Ų16154.6 Ų54.661%0.6127%0.268SS*.G310 helixtrans-62.2-18.4172.770.1-89.1000113.5A246 F252 L283A246-W248 PolarHBondContact O-N 3.21Å; W248-F252 HydrophobicContact CZ3-CE2 4.45Å; W248-L283 HydrophobicContact CH2-CD1 4.33Å; W248-L283 HydrophobicContact CZ3-CD1 4.41Å
249L94.7Very high95.9Very high0 Ų048.1 Ų48.10%024%0.237CC..G310 helixtrans-91.2-3.1175.3-72.1175.9000114.1I242 A246 S247 D251 F252 L281 L283 I439I242-L249 HydrophobicContact CG2-CB 4.37Å; A246-L249 HydrophobicContact CB-CD1 4.17Å; A246-L249 WeakPolarHBondContact O-CB 3.36Å; A246-L249 PolarHBondContact O-N 2.81Å; S247-L249 PolarHBondContact O-N 3.16Å; L249-D251 PolarHBondContact O-N 2.62Å; L249-F252 HydrophobicContact CD2-CB 4.48Å; L249-F252 HydrophobicContact CD2-CD1 4.48Å; L249-F252 HydrophobicContact CD2-CD2 3.76Å; L249-F252 HydrophobicContact CD2-CE2 4.03Å; L249-F252 HydrophobicContact CD2-CG 3.99Å; L249-F252 HydrophobicContact CD2-CZ 4.5Å; L249-F252 WeakPolarHBondContact O-CB 3.43Å; L249-F252 PolarHBondContact O-N 2.76Å; L249-L281 HydrophobicContact CD1-CB 3.77Å; L249-L281 HydrophobicContact CD1-CD1 3.74Å; L249-L281 HydrophobicContact CD1-CG 4.29Å; L249-L283 HydrophobicContact CD2-CD1 4Å; L249-L283 HydrophobicContact CD2-CD2 3.85Å; L249-L283 HydrophobicContact CD2-CG 4.14Å; L249-I439 HydrophobicContact CB-CD1 4Å
250K91.8Very high96.1Very high98 Ų9843.5 Ų43.543%0.42621%0.212SC..THydrogen-bonded Turntrans-55.6-30.2-169.572-175.9-178.963.80115M243 S247M243-K250 HydrophobicContact CE-CD 4.19Å; M243-K250 HydrophobicContact SD-CB 3.59Å; M243-K250 VanDerWaalsContact SD-CB 3.59Å; M243-K250 HydrophobicContact SD-CD 4.02Å; M243-K250 HydrophobicContact SD-CG 4.44Å; S247-K250 VanDerWaalsContact O-CB 3.26Å; S247-K250 WeakPolarHBondContact O-CB 3.06Å; S247-K250 VanDerWaalsContact O-CG 3.22Å; S247-K250 WeakPolarHBondContact O-CG 3.39Å; S247-K250 PolarHBondContact O-N 3.42Å; S247-K250 VanDerWaalsContact O-N 3.08Å
251D91.5Very high96.1Very high111 Ų11145.2 Ų45.259%0.59422%0.223SC*.THydrogen-bonded Turntrans-96.8-4.2-177-59.8-45000112.9L249L249-D251 PolarHBondContact O-N 2.62Å
252F95.7Very high96.2Very high59 Ų5945.1 Ų45.126%0.25922%0.223SC..SBendtrans-72.9139.4177.6-81.2-106.9000111W248 L249 L283 P437 I439W248-F252 HydrophobicContact CZ3-CE2 4.45Å; L249-F252 HydrophobicContact CD2-CB 4.48Å; L249-F252 HydrophobicContact CD2-CD1 4.48Å; L249-F252 HydrophobicContact CD2-CD2 3.76Å; L249-F252 HydrophobicContact CD2-CE2 4.03Å; L249-F252 HydrophobicContact CD2-CG 3.99Å; L249-F252 HydrophobicContact CD2-CZ 4.5Å; L249-F252 WeakPolarHBondContact O-CB 3.43Å; L249-F252 PolarHBondContact O-N 2.76Å; F252-L283 HydrophobicContact CD1-CD1 4.11Å; F252-L283 HydrophobicContact CD1-CD2 3.74Å; F252-L283 HydrophobicContact CE1-CD1 3.72Å; F252-L283 HydrophobicContact CE1-CD2 4.22Å; F252-L283 HydrophobicContact CG-CD2 4.29Å; F252-L283 HydrophobicContact CZ-CD1 4.22Å; F252-P437 HydrophobicContact CE1-CB 4.26Å; F252-I439 HydrophobicContact CB-CD1 4.02Å; F252-I439 HydrophobicContact CB-CG1 3.82Å
253P97.5Very high96.1Very high9 Ų946 Ų466%0.05823%0.229CC..  trans-66.9158.616926.6-31000111.1K297 K299 T436 V438 I439P253-K297 CarbonylContact C-O 3.25Å; P253-K297 WeakPolarHBondContact CA-O 3.28Å; P253-K297 WeakPolarHBondContact CB-O 3.49Å; P253-K299 HydrophobicContact CB-CD 3.73Å; P253-K299 VanDerWaalsContact CB-CE 3.49Å; P253-K299 HydrophobicContact CB-CG 3.94Å; P253-K299 HydrophobicContact CG-CD 3.83Å; P253-K299 VanDerWaalsContact CG-CE 3.46Å; P253-T436 HydrophobicContact CG-CG2 4.26Å; P253-V438 HydrophobicContact CB-CG1 4.07Å; P253-V438 HydrophobicContact CG-CG1 3.79Å; P253-V438 CarbonylContact O-C 3.58Å; P253-V438 WeakPolarHBondContact O-CA 3.32Å; P253-I439 PolarHBondContact O-N 2.95Å
254T98.1Very high96.2Very high0 Ų042.7 Ų42.70%021%0.213CC..BIsolated β-bridgetrans-124.9158.8-179.5-173.20000111.8S233 N234 N256 K297 T298 K299 I439S233-T254 WeakPolarHBondContact O-CB 3.31Å; S233-T254 PolarHBondContact O-OG1 3.23Å; N234-T254 HydrophobicContact CB-CG2 3.9Å; N234-T254 VanDerWaalsContact CG-CG2 3.5Å; T254-N256 WeakPolarHBondContact OG1-CB 3.37Å; T254-N256 PolarHBondContact OG1-N 3.36Å; T254-N256 PolarHBondContact OG1-ND2 3.44Å; T254-K297 PolarHBondContact N-O 3.36Å; T254-T298 CarbonylContact O-C 3.58Å; T254-T298 VanDerWaalsContact O-CA 3.24Å; T254-T298 WeakPolarHBondContact O-CA 3.35Å; T254-K299 PolarHBondContact O-N 2.98Å; T254-I439 CarbonylContact C-O 3.59Å; T254-I439 VanDerWaalsContact CA-O 3.26Å; T254-I439 WeakPolarHBondContact CA-O 3.11Å; T254-I439 PolarHBondContact OG1-O 2.8Å; T254-I439 VanDerWaalsContact OG1-O 3.08Å
255T97.8Very high96.3Very high17 Ų1737.6 Ų37.610%0.10419%0.189CC..SBendtrans-98.7-2.7168.958.50000113.4K299 L301 V438 I439 H440T255-K299 WeakPolarHBondContact CA-O 3.29Å; T255-L301 HydrophobicContact CG2-CB 3.98Å; T255-L301 HydrophobicContact CG2-CD1 3.99Å; T255-V438 HydrophobicContact CG2-CB 4.05Å; T255-V438 HydrophobicContact CG2-CG2 3.55Å; T255-I439 PolarHBondContact N-O 3.18Å; T255-H440 PolarHBondContact OG1-ND1 2.76Å
256N98Very high96.3Very high4 Ų437 Ų372%0.02119%0.188CC..SBendtrans-82.9152.4-171.6-71.3-85.9000111.4N67 S233 N234 T254 A260 T298 I439 H440N67-N256 PolarHBondContact ND2-OD1 2.95Å; S233-N256 VanDerWaalsContact CB-ND2 3.31Å; S233-N256 WeakPolarHBondContact CB-ND2 3.36Å; N234-N256 HydrophobicContact CB-CB 3.92Å; N234-N256 PolarHBondContact ND2-O 3.11Å; T254-N256 WeakPolarHBondContact OG1-CB 3.37Å; T254-N256 PolarHBondContact OG1-N 3.36Å; T254-N256 PolarHBondContact OG1-ND2 3.44Å; N256-A260 HydrophobicContact CB-CB 3.94Å; N256-T298 WeakPolarHBondContact O-CG2 3.45Å; N256-I439 PolarHBondContact ND2-O 3.28Å; N256-H440 PolarHBondContact ND2-O 2.85Å
257G96.1Very high96.4Very high1 Ų137.6 Ų37.61%0.0119%0.191CC..  trans-69.6159.7170.700000112N67 N234 Y259 A260N67-G257 PolarHBondContact OD1-N 3.33Å; N234-G257 VanDerWaalsContact CB-O 3.27Å; N234-G257 WeakPolarHBondContact CB-O 3.44Å; N234-G257 VanDerWaalsContact ND2-C 3.27Å; N234-G257 PolarHBondContact ND2-O 3.34Å; G257-Y259 PolarHBondContact O-N 3.39Å; G257-Y259 VanDerWaalsContact O-N 3.13Å; G257-A260 WeakPolarHBondContact O-CB 3.39Å; G257-A260 PolarHBondContact O-N 3.01Å; G257-A260 VanDerWaalsContact O-N 3.08Å
258P95.3Very high96.5Very high93 Ų9334.6 Ų34.660%0.60417%0.17SC*.THydrogen-bonded Turntrans-63-19.3-177.427.3-35.6000113.2A260 T261P258-A260 VanDerWaalsContact C-N 3.27Å; P258-A260 PolarHBondContact O-N 3.29Å; P258-T261 WeakPolarHBondContact O-CG2 3.3Å
259Y95Very high96.7Very high34 Ų3432 Ų3213%0.13316%0.16CC..THydrogen-bonded Turntrans-72.2-10.6174.843.1-104.2000114.8E61 G66 N67 K70 G257 T261E61-Y259 VanDerWaalsContact CD-CD1 3.48Å; E61-Y259 HydrophobicContact CG-CD1 3.53Å; E61-Y259 HydrophobicContact CG-CE1 4.13Å; E61-Y259 HydrophobicContact CG-CG 4.13Å; G66-Y259 WeakPolarHBondContact CA-OH 3.45Å; G66-Y259 PolarHBondContact O-OH 2.92Å; N67-Y259 PolarHBondContact N-OH 3.21Å; K70-Y259 VanDerWaalsContact CE-OH 3.27Å; K70-Y259 WeakPolarHBondContact CE-OH 3.27Å; K70-Y259 PolarHBondContact NZ-OH 2.91Å; K70-Y259 VanDerWaalsContact NZ-OH 3.08Å; G257-Y259 PolarHBondContact O-N 3.39Å; G257-Y259 VanDerWaalsContact O-N 3.13Å; Y259-T261 PolarHBondContact O-N 2.96Å
260A97.4Very high96.7Very high1 Ų139.7 Ų39.71%0.00819%0.19CC..  trans-7964.6179.300000111.6G231 Y232 S233 N234 N256 G257 P258G231-A260 CarbonylContact O-C 3.57Å; G231-A260 WeakPolarHBondContact O-CA 3.46Å; Y232-A260 CarbonylContact C-O 3.46Å; Y232-A260 WeakPolarHBondContact CA-O 3.5Å; S233-A260 PolarHBondContact N-O 3.44Å; N234-A260 CarbonylContact C-O 3.53Å; N234-A260 HydrophobicContact CB-CB 4.21Å; N234-A260 PolarHBondContact N-O 3.15Å; N256-A260 HydrophobicContact CB-CB 3.94Å; G257-A260 WeakPolarHBondContact O-CB 3.39Å; G257-A260 PolarHBondContact O-N 3.01Å; G257-A260 VanDerWaalsContact O-N 3.08Å; P258-A260 VanDerWaalsContact C-N 3.27Å; P258-A260 PolarHBondContact O-N 3.29Å
261T96.7Very high96.9Very high37 Ų3736.6 Ų36.623%0.22718%0.179CC..SBendtrans-103.5-0.2-17058.80000114.8G231 P258 Y259 S263 K266G231-T261 PolarHBondContact O-N 3.34Å; P258-T261 WeakPolarHBondContact O-CG2 3.3Å; Y259-T261 PolarHBondContact O-N 2.96Å; T261-S263 VanDerWaalsContact C-N 3.33Å; T261-S263 PolarHBondContact O-N 3.5Å; T261-K266 WeakPolarHBondContact O-CE 3.22Å; T261-K266 PolarHBondContact O-NZ 3.31Å
262G98Very high97.2Very high1 Ų132.2 Ų32.21%0.0116%0.161CC..  trans70.824.2-176.300000114.3G231 G264 I265 K266G231-G262 WeakPolarHBondContact O-CA 3.41Å; G231-G262 PolarHBondContact O-N 2.74Å; G262-G264 VanDerWaalsContact C-N 3.34Å; G262-G264 PolarHBondContact O-N 3.47Å; G262-I265 WeakPolarHBondContact O-CB 3.39Å; G262-I265 PolarHBondContact O-N 2.88Å; G262-I265 VanDerWaalsContact O-N 3.08Å; G262-K266 WeakPolarHBondContact O-CG 3.5Å; G262-K266 PolarHBondContact O-N 3.37Å
263S97Very high97.3Very high23 Ų2329.8 Ų29.816%0.16115%0.152CC..Hα-helixtrans-53.9-46.1-178.957.80000112.9T261 I265 K266 M267T261-S263 VanDerWaalsContact C-N 3.33Å; T261-S263 PolarHBondContact O-N 3.5Å; S263-I265 PolarHBondContact O-N 3.37Å; S263-K266 PolarHBondContact O-N 3.45Å; S263-M267 WeakPolarHBondContact O-CG 3.15Å; S263-M267 PolarHBondContact O-N 3.46Å
264G98.7Very high97.4Very high0 Ų034.1 Ų34.10%017%0.17CC..Hα-helixtrans-63.5-38.3175.900000113.2T229 G262 M267 A268T229-G264 VanDerWaalsContact OG1-CA 3.23Å; T229-G264 WeakPolarHBondContact OG1-CA 3.3Å; T229-G264 PolarHBondContact OG1-N 2.97Å; T229-G264 VanDerWaalsContact OG1-N 3.1Å; G262-G264 VanDerWaalsContact C-N 3.34Å; G262-G264 PolarHBondContact O-N 3.47Å; G264-M267 PolarHBondContact O-N 2.91Å; G264-A268 VanDerWaalsContact O-CB 3.28Å; G264-A268 WeakPolarHBondContact O-CB 3.46Å; G264-A268 PolarHBondContact O-N 2.84Å
265I98.8Very high97.4Very high0 Ų035.7 Ų35.70%018%0.178CC..Hα-helixtrans-64.1-45.5175.1-67.9162000110.5Y232 L241 G262 S263 A268 R269 L275 M278 I446 V471Y232-I265 HydrophobicContact CD1-CD1 3.49Å; Y232-I265 VanDerWaalsContact CD1-CD1 3.49Å; Y232-I265 HydrophobicContact CE1-CD1 3.93Å; L241-I265 HydrophobicContact CD1-CB 4Å; L241-I265 HydrophobicContact CD1-CD1 4.4Å; L241-I265 HydrophobicContact CD1-CG2 3.69Å; G262-I265 WeakPolarHBondContact O-CB 3.39Å; G262-I265 PolarHBondContact O-N 2.88Å; G262-I265 VanDerWaalsContact O-N 3.08Å; S263-I265 PolarHBondContact O-N 3.37Å; I265-A268 PolarHBondContact O-N 3.28Å; I265-R269 VanDerWaalsContact O-CB 3.3Å; I265-R269 WeakPolarHBondContact O-CB 3.18Å; I265-R269 PolarHBondContact O-N 3.17Å; I265-L275 HydrophobicContact CG2-CD1 3.76Å; I265-L275 HydrophobicContact CG2-CD2 3.84Å; I265-L275 HydrophobicContact CG2-CG 4.47Å; I265-M278 HydrophobicContact CD1-CE 4.44Å; I265-M278 HydrophobicContact CG2-CE 3.94Å; I265-M278 HydrophobicContact CG2-SD 4.45Å; I265-I446 HydrophobicContact CG1-CG1 4.23Å; I265-V471 HydrophobicContact CG1-CG2 3.83Å
266K98Very high97.4Very high65 Ų6537.9 Ų37.928%0.28319%0.188SC..Hα-helixtrans-60.8-45.9177.7-67173.5-171.6178.60110.8D235 L241 T261 G262 S263 Y270D235-K266 IonicContact OD2-NZ 2.82Å; D235-K266 PolarHBondContact OD2-NZ 2.95Å; L241-K266 HydrophobicContact CD1-CG 4.31Å; L241-K266 HydrophobicContact CD2-CG 4.45Å; L241-K266 HydrophobicContact CG-CG 4.44Å; T261-K266 WeakPolarHBondContact O-CE 3.22Å; T261-K266 PolarHBondContact O-NZ 3.31Å; G262-K266 WeakPolarHBondContact O-CG 3.5Å; G262-K266 PolarHBondContact O-N 3.37Å; S263-K266 PolarHBondContact O-N 3.45Å; K266-Y270 PolarHBondContact O-N 3.14Å
267M98.3Very high97.4Very high13 Ų1338.9 Ų38.96%0.06419%0.193CC..Hα-helixtrans-62.4-46.9175.9-73.4-168.3-69.900112.7V35 A194 S196 L197 L227 S263 G264 Y270V35-M267 HydrophobicContact CG1-CE 4.33Å; A194-M267 HydrophobicContact CB-CE 4.16Å; A194-M267 HydrophobicContact CB-SD 4.3Å; S196-M267 PolarHBondContact N-SD 3.23Å; S196-M267 VanDerWaalsContact N-SD 3.4Å; L197-M267 HydrophobicContact CD1-CB 4.36Å; L197-M267 HydrophobicContact CG-CB 4.24Å; L227-M267 HydrophobicContact CD2-CE 3.92Å; S263-M267 WeakPolarHBondContact O-CG 3.15Å; S263-M267 PolarHBondContact O-N 3.46Å; G264-M267 PolarHBondContact O-N 2.91Å; M267-Y270 WeakPolarHBondContact O-CB 3.26Å; M267-Y270 PolarHBondContact O-N 3.12Å
268A98.6Very high97.5Very high0 Ų039.3 Ų39.30%020%0.195CC..Hα-helixtrans-65.3-40.8-179.800000111.9L227 G264 I265 Y270 V271 G272 A273 I446L227-A268 HydrophobicContact CD1-CB 3.82Å; G264-A268 VanDerWaalsContact O-CB 3.28Å; G264-A268 WeakPolarHBondContact O-CB 3.46Å; G264-A268 PolarHBondContact O-N 2.84Å; I265-A268 PolarHBondContact O-N 3.28Å; A268-Y270 PolarHBondContact O-N 3.05Å; A268-V271 VanDerWaalsContact O-CG2 3.22Å; A268-V271 WeakPolarHBondContact O-CG2 3.38Å; A268-V271 PolarHBondContact O-N 3.25Å; A268-V271 VanDerWaalsContact O-N 3.17Å; A268-G272 PolarHBondContact O-N 3.35Å; A268-A273 VanDerWaalsContact C-CB 3.49Å; A268-A273 HydrophobicContact CB-CB 3.69Å; A268-A273 WeakPolarHBondContact O-CB 3.32Å; A268-A273 PolarHBondContact O-N 3.1Å; A268-I446 HydrophobicContact CB-CD1 3.38Å; A268-I446 HydrophobicContact CB-CG1 3.75Å
269R97.5Very high97.6Very high105 Ų10538.6 Ų38.640%0.39619%0.187SC..Hα-helixtrans-56.7-39.6175.8-172.7176.782.1-177.22111.4I265 V271 G272 L275I265-R269 VanDerWaalsContact O-CB 3.3Å; I265-R269 WeakPolarHBondContact O-CB 3.18Å; I265-R269 PolarHBondContact O-N 3.17Å; R269-V271 VanDerWaalsContact C-N 3.28Å; R269-V271 PolarHBondContact O-N 2.87Å; R269-G272 PolarHBondContact O-N 3.28Å; R269-L275 HydrophobicContact CB-CD1 4.26Å; R269-L275 HydrophobicContact CG-CD1 4.21Å
270Y95.8Very high97.6Very high163 Ų16340.4 Ų40.464%0.63919%0.193SC*.Hα-helixtrans-62.5-34-179.4-169.1-95.2000113K266 M267 A268 G272 V520K266-Y270 PolarHBondContact O-N 3.14Å; M267-Y270 WeakPolarHBondContact O-CB 3.26Å; M267-Y270 PolarHBondContact O-N 3.12Å; A268-Y270 PolarHBondContact O-N 3.05Å; Y270-G272 VanDerWaalsContact C-N 3.27Å; Y270-G272 PolarHBondContact O-N 2.79Å; Y270-V520 VanDerWaalsContact OH-CB 3.24Å; Y270-V520 WeakPolarHBondContact OH-CB 3.36Å; Y270-V520 VanDerWaalsContact OH-CG2 3.31Å; Y270-V520 WeakPolarHBondContact OH-CG2 3.47Å
271V96Very high97.7Very high32 Ų3241 Ų4119%0.19420%0.196CC..THydrogen-bonded Turntrans-91.117.2176-57.70000113.2L197 T199 A268 R269 I462 L465L197-V271 HydrophobicContact CB-CG1 3.97Å; L197-V271 HydrophobicContact CD1-CB 4.5Å; L197-V271 HydrophobicContact CD1-CG1 4.06Å; L197-V271 HydrophobicContact CD1-CG2 3.58Å; T199-V271 HydrophobicContact CG2-CB 4.33Å; T199-V271 HydrophobicContact CG2-CG1 3.61Å; A268-V271 VanDerWaalsContact O-CG2 3.22Å; A268-V271 WeakPolarHBondContact O-CG2 3.38Å; A268-V271 PolarHBondContact O-N 3.25Å; A268-V271 VanDerWaalsContact O-N 3.17Å; R269-V271 VanDerWaalsContact C-N 3.28Å; R269-V271 PolarHBondContact O-N 2.87Å; V271-I462 HydrophobicContact CG2-CD1 4.3Å; V271-L465 HydrophobicContact CG2-CD2 3.9Å
272G96.9Very high97.7Very high20 Ų2039.3 Ų39.321%0.20619%0.186CC..THydrogen-bonded Turntrans84.413.9174.200000115.4A268 R269 Y270 K274 N456 F457A268-G272 PolarHBondContact O-N 3.35Å; R269-G272 PolarHBondContact O-N 3.28Å; Y270-G272 VanDerWaalsContact C-N 3.27Å; Y270-G272 PolarHBondContact O-N 2.79Å; G272-K274 PolarHBondContact O-N 2.86Å; G272-N456 VanDerWaalsContact O-CA 3.22Å; G272-N456 WeakPolarHBondContact O-CA 3.44Å; G272-N456 VanDerWaalsContact O-CB 3.28Å; G272-N456 WeakPolarHBondContact O-CB 3.3Å; G272-F457 WeakPolarHBondContact O-CD1 3.42Å; G272-F457 PolarHBondContact O-N 3.18Å
273A98.6Very high97.7Very high8 Ų840.2 Ų40.27%0.06619%0.19CC..BIsolated β-bridgetrans-60.7136.6174.500000111.1A268 I446 V454 I462A268-A273 VanDerWaalsContact C-CB 3.49Å; A268-A273 HydrophobicContact CB-CB 3.69Å; A268-A273 WeakPolarHBondContact O-CB 3.32Å; A268-A273 PolarHBondContact O-N 3.1Å; A273-I446 HydrophobicContact CB-CG2 4.27Å; A273-V454 HydrophobicContact CB-CG1 3.51Å; A273-I462 HydrophobicContact CB-CD1 4.09Å
274K98.6Very high97.8Very high100 Ų10039.1 Ų39.144%0.43518%0.182SC..  trans-73.5135.9173.5-173.8175.7179.9175.30109.4G272 V447 I455G272-K274 PolarHBondContact O-N 2.86Å; K274-V447 HydrophobicContact CB-CB 4.19Å; K274-V447 HydrophobicContact CB-CG2 4.13Å; K274-V447 HydrophobicContact CD-CG2 4.22Å; K274-V447 HydrophobicContact CG-CB 4.45Å; K274-V447 HydrophobicContact CG-CG2 3.91Å; K274-V447 WeakPolarHBondContact O-CG2 3.46Å; K274-V447 PolarHBondContact O-N 3.33Å; K274-I455 WeakPolarHBondContact CB-O 3.47Å; K274-I455 PolarHBondContact N-O 3.43Å
275L98.6Very high97.8Very high33 Ų3339.1 Ų39.117%0.17318%0.182CC..EExtended strand (participates in β ladder)trans-106.6153.1172.4-53.9-175.4000110.5I265 R269 M278 G445 I446I265-L275 HydrophobicContact CG2-CD1 3.76Å; I265-L275 HydrophobicContact CG2-CD2 3.84Å; I265-L275 HydrophobicContact CG2-CG 4.47Å; R269-L275 HydrophobicContact CB-CD1 4.26Å; R269-L275 HydrophobicContact CG-CD1 4.21Å; L275-M278 HydrophobicContact CB-CG 3.71Å; L275-M278 HydrophobicContact CB-SD 3.9Å; L275-M278 HydrophobicContact CD1-CE 4.37Å; L275-M278 HydrophobicContact CD1-CG 4.14Å; L275-M278 HydrophobicContact CD1-SD 4.04Å; L275-M278 HydrophobicContact CG-SD 4.42Å; L275-G445 VanDerWaalsContact CA-O 3.31Å; L275-G445 WeakPolarHBondContact CA-O 3.44Å; L275-I446 HydrophobicContact CD2-CG1 4.2Å
276I98.3Very high97.7Very high62 Ų6239.1 Ų39.132%0.31818%0.183SC..EExtended strand (participates in β ladder)trans-139.2152.5177.6-166.4160.4000110.3M278 G444 G445 V447I276-M278 PolarHBondContact O-N 3.35Å; I276-G444 CarbonylContact O-C 3.57Å; I276-G444 WeakPolarHBondContact O-CA 3.45Å; I276-G445 PolarHBondContact N-O 3.21Å; I276-G445 PolarHBondContact O-N 3.45Å; I276-V447 HydrophobicContact CB-CG2 3.68Å; I276-V447 HydrophobicContact CG2-CG2 3.68Å
277D97.7Very high97.8Very high25 Ų2536 Ų3613%0.13417%0.169CC..  trans52.427.3174.5-54.7-33.2000115.1M106 N279 R280 G444M106-D277 WeakPolarHBondContact CE-OD1 3.34Å; D277-N279 PolarHBondContact O-N 3.07Å; D277-R280 HydrophobicContact CB-CB 4.22Å; D277-R280 HydrophobicContact CB-CG 4.09Å; D277-R280 VanDerWaalsContact O-CB 3.31Å; D277-R280 WeakPolarHBondContact O-CB 3.42Å; D277-R280 PolarHBondContact O-N 3.16Å; D277-G444 VanDerWaalsContact C-CA 3.48Å; D277-G444 VanDerWaalsContact O-CA 3.25Å; D277-G444 WeakPolarHBondContact O-CA 3.48Å; D277-G444 PolarHBondContact O-N 3Å
278M98Very high97.8Very high11 Ų1135.5 Ų35.55%0.05417%0.167CC..THydrogen-bonded Turntrans-62.7-18.9-173.7-66-54.8-56.300114.3Y232 L241 Y245 I265 L275 I276 R280 G445Y232-M278 HydrophobicContact CD1-CE 4.12Å; Y232-M278 HydrophobicContact CE1-CE 3.56Å; Y232-M278 HydrophobicContact CE1-SD 4.38Å; Y232-M278 HydrophobicContact CE2-CE 4.36Å; Y232-M278 PolarHBondContact OH-O 3.28Å; L241-M278 HydrophobicContact CD1-CE 4.02Å; Y245-M278 WeakPolarHBondContact CB-O 3.31Å; Y245-M278 HydrophobicContact CD1-CB 3.54Å; Y245-M278 HydrophobicContact CD2-CB 3.83Å; Y245-M278 HydrophobicContact CD2-CE 4.26Å; Y245-M278 HydrophobicContact CE1-CB 3.85Å; Y245-M278 HydrophobicContact CE1-CG 4.35Å; Y245-M278 HydrophobicContact CE2-CB 4.13Å; Y245-M278 HydrophobicContact CE2-CE 4.29Å; Y245-M278 HydrophobicContact CE2-CG 4.42Å; Y245-M278 HydrophobicContact CG-CB 3.53Å; I265-M278 HydrophobicContact CD1-CE 4.44Å; I265-M278 HydrophobicContact CG2-CE 3.94Å; I265-M278 HydrophobicContact CG2-SD 4.45Å; L275-M278 HydrophobicContact CB-CG 3.71Å; L275-M278 HydrophobicContact CB-SD 3.9Å; L275-M278 HydrophobicContact CD1-CE 4.37Å; L275-M278 HydrophobicContact CD1-CG 4.14Å; L275-M278 HydrophobicContact CD1-SD 4.04Å; L275-M278 HydrophobicContact CG-SD 4.42Å; I276-M278 PolarHBondContact O-N 3.35Å; M278-R280 VanDerWaalsContact C-N 3.31Å; M278-G445 PolarHBondContact SD-N 2.96Å
279N96.8Very high97.8Very high78 Ų7835.6 Ų35.642%0.41717%0.167SC..THydrogen-bonded Turntrans-88.74.5174.566.4-23.6000113.3Y245 D277Y245-N279 WeakPolarHBondContact O-CA 3.11Å; Y245-N279 WeakPolarHBondContact O-CB 3.41Å; D277-N279 PolarHBondContact O-N 3.07Å
280R96.6Very high97.8Very high71 Ų7131.9 Ų31.927%0.26816%0.155SC..  trans-107.6114.1-178.3-59.4-58.1-175-170.31.5110.2Y232 D277 M278 M443Y232-R280 PolarHBondContact OH-O 2.97Å; D277-R280 HydrophobicContact CB-CB 4.22Å; D277-R280 HydrophobicContact CB-CG 4.09Å; D277-R280 VanDerWaalsContact O-CB 3.31Å; D277-R280 WeakPolarHBondContact O-CB 3.42Å; D277-R280 PolarHBondContact O-N 3.16Å; M278-R280 VanDerWaalsContact C-N 3.31Å; R280-M443 HydrophobicContact CB-CB 3.6Å; R280-M443 HydrophobicContact CB-CG 4.02Å; R280-M443 VanDerWaalsContact O-CB 3.24Å; R280-M443 WeakPolarHBondContact O-CB 3.43Å; R280-M443 PolarHBondContact O-N 3.36Å
281L97.7Very high97.7Very high14 Ų1428 Ų287%0.07315%0.149CC..EExtended strand (participates in β ladder)trans-125.5132.4165.1-60.195000108.1Y232 I242 A246 L249 L283 I439 Y441Y232-L281 HydrophobicContact CD2-CD2 4.19Å; Y232-L281 HydrophobicContact CE2-CD1 3.93Å; Y232-L281 HydrophobicContact CE2-CD2 3.91Å; Y232-L281 HydrophobicContact CE2-CG 4.01Å; I242-L281 HydrophobicContact CD1-CD2 4.24Å; I242-L281 HydrophobicContact CG1-CD2 4.03Å; A246-L281 HydrophobicContact CB-CD1 3.41Å; A246-L281 VanDerWaalsContact CB-CD1 3.41Å; L249-L281 HydrophobicContact CD1-CB 3.77Å; L249-L281 HydrophobicContact CD1-CD1 3.74Å; L249-L281 HydrophobicContact CD1-CG 4.29Å; L281-L283 PolarHBondContact O-N 2.88Å; L281-I439 HydrophobicContact CB-CG2 4.13Å; L281-I439 HydrophobicContact CD2-CG2 3.73Å; L281-Y441 CarbonylContact C-O 3.56Å; L281-Y441 WeakPolarHBondContact CA-O 3.46Å
282Q98Very high97.7Very high2 Ų233.6 Ų33.61%0.00917%0.171CC..EExtended strand (participates in β ladder)trans-71.6129.2176.2166.717285.400109.7R328 H440 Y441 M443 D479 R480Q282-R328 VanDerWaalsContact CD-NH1 3.33Å; Q282-H440 PolarHBondContact O-N 2.78Å; Q282-H440 PolarHBondContact OE1-CD2 2.92Å; Q282-Y441 PolarHBondContact N-O 2.93Å; Q282-M443 HydrophobicContact CB-CG 4.36Å; Q282-M443 HydrophobicContact CB-SD 3.79Å; Q282-D479 WeakPolarHBondContact CB-OD1 3.34Å; Q282-D479 VanDerWaalsContact CD-OD1 3.27Å; Q282-D479 WeakPolarHBondContact CG-OD1 3.49Å; Q282-D479 PolarHBondContact NE2-OD1 2.91Å; Q282-R480 PolarHBondContact NE2-O 3.43Å
283L97.9Very high97.7Very high19 Ų1937.6 Ų37.610%0.09918%0.184CC..EExtended strand (participates in β ladder)trans-89.3122.1160.8-66.8178.1000109.1W248 L249 F252 L281 T332 V438 I439W248-L283 HydrophobicContact CH2-CD1 4.33Å; W248-L283 HydrophobicContact CZ3-CD1 4.41Å; L249-L283 HydrophobicContact CD2-CD1 4Å; L249-L283 HydrophobicContact CD2-CD2 3.85Å; L249-L283 HydrophobicContact CD2-CG 4.14Å; F252-L283 HydrophobicContact CD1-CD1 4.11Å; F252-L283 HydrophobicContact CD1-CD2 3.74Å; F252-L283 HydrophobicContact CE1-CD1 3.72Å; F252-L283 HydrophobicContact CE1-CD2 4.22Å; F252-L283 HydrophobicContact CG-CD2 4.29Å; F252-L283 HydrophobicContact CZ-CD1 4.22Å; L281-L283 PolarHBondContact O-N 2.88Å; L283-T332 HydrophobicContact CB-CG2 3.8Å; L283-T332 HydrophobicContact CD1-CG2 3.75Å; L283-T332 HydrophobicContact CG-CG2 4.44Å; L283-T332 PolarHBondContact O-OG1 3.09Å; L283-V438 CarbonylContact C-O 3.15Å; L283-V438 VanDerWaalsContact CA-O 3.31Å; L283-V438 WeakPolarHBondContact CA-O 3.37Å; L283-I439 HydrophobicContact CD2-CB 4.46Å; L283-I439 HydrophobicContact CD2-CG1 3.87Å
284H98.1Very high97.6Very high0 Ų038.5 Ų38.50%019%0.19CC..EExtended strand (participates in β ladder)trans-83.2133.7165.7-168.5-90.2000108.6T286 L301 A302 E304 R328 P437 V438 H440H284-T286 PolarHBondContact CE1-OG1 2.89Å; H284-T286 PolarHBondContact ND1-N 3.14Å; H284-T286 PolarHBondContact ND1-O 2.88Å; H284-T286 PolarHBondContact ND1-OG1 3.27Å; H284-T286 PolarHBondContact O-N 3.12Å; H284-T286 VanDerWaalsContact O-N 3.16Å; H284-L301 HydrophobicContact CB-CD1 4.02Å; H284-L301 VanDerWaalsContact ND1-CD1 3.29Å; H284-L301 WeakPolarHBondContact ND1-CD1 3.47Å; H284-A302 PolarHBondContact CE1-O 3.4Å; H284-E304 IonicContact CD2-OE2 2.7Å; H284-E304 IonicContact NE2-OE2 3.13Å; H284-E304 PolarHBondContact NE2-OE2 3.06Å; H284-E304 VanDerWaalsContact NE2-OE2 3.09Å; H284-R328 PolarHBondContact CD2-NE 3Å; H284-R328 PolarHBondContact CD2-NH2 3.44Å; H284-P437 WeakPolarHBondContact O-CA 3.29Å; H284-V438 HydrophobicContact CB-CG2 4.03Å; H284-V438 PolarHBondContact N-O 3.39Å; H284-V438 WeakPolarHBondContact O-CG2 3.39Å; H284-V438 PolarHBondContact O-N 3.21Å; H284-H440 HydrophobicContact CB-CB 3.65Å
285P98.3Very high97.5Very high0 Ų038.5 Ų38.50%019%0.194CC..EExtended strand (participates in β ladder)trans-67.2-21.6-173.325.1-35.5000113.2V331 T332 I335 T436P285-V331 HydrophobicContact CB-CB 3.93Å; P285-V331 HydrophobicContact CB-CG1 3.55Å; P285-V331 HydrophobicContact CG-CB 4.07Å; P285-V331 HydrophobicContact CG-CG1 3.93Å; P285-T332 WeakPolarHBondContact CA-OG1 3.42Å; P285-I335 HydrophobicContact CB-CD1 3.69Å; P285-I335 WeakPolarHBondContact O-CD1 3.43Å; P285-T436 CarbonylContact O-C 3.57Å
286T98.5Very high97.4Very high1 Ų138.3 Ų38.31%0.00620%0.198CC..EExtended strand (participates in β ladder)trans-128.188.4-170.562.90000113.2H284 A302 L313 V435H284-T286 PolarHBondContact CE1-OG1 2.89Å; H284-T286 PolarHBondContact ND1-N 3.14Å; H284-T286 PolarHBondContact ND1-O 2.88Å; H284-T286 PolarHBondContact ND1-OG1 3.27Å; H284-T286 PolarHBondContact O-N 3.12Å; H284-T286 VanDerWaalsContact O-N 3.16Å; T286-A302 WeakPolarHBondContact O-CB 3.18Å; T286-A302 PolarHBondContact O-N 2.91Å; T286-A302 PolarHBondContact OG1-O 2.97Å; T286-A302 VanDerWaalsContact OG1-O 3.08Å; T286-L313 HydrophobicContact CG2-CD1 4.4Å; T286-L313 HydrophobicContact CG2-CD2 4.1Å; T286-V435 HydrophobicContact CG2-CB 4.2Å; T286-V435 HydrophobicContact CG2-CG2 3.88Å
287G98.5Very high97.3Very high0 Ų041.7 Ų41.70%021%0.21CC..EExtended strand (participates in β ladder)trans-97.6130.1156.800000110.2V289 F300 V435 T436G287-V289 PolarHBondContact O-N 3.23Å; G287-F300 CarbonylContact C-O 3.12Å; G287-V435 CarbonylContact O-C 3.15Å; G287-V435 VanDerWaalsContact O-CA 3.25Å; G287-V435 WeakPolarHBondContact O-CA 3.13Å; G287-T436 PolarHBondContact N-O 3.1Å; G287-T436 PolarHBondContact O-N 3.46Å
288F98.6Very high97.3Very high2 Ų243.8 Ų43.81%0.00922%0.224CC..EExtended strand (participates in β ladder)trans-60.6131.4177.3-73.8-61.3000110.8F300 A302 L306 Y370 F376 F377 A433 V435F288-F300 HydrophobicContact CD2-CB 4.17Å; F288-F300 PolarHBondContact N-O 2.57Å; F288-A302 HydrophobicContact CD1-CB 3.92Å; F288-A302 HydrophobicContact CD2-CB 3.86Å; F288-A302 HydrophobicContact CE1-CB 3.65Å; F288-A302 HydrophobicContact CE2-CB 3.62Å; F288-A302 HydrophobicContact CG-CB 4.02Å; F288-A302 HydrophobicContact CZ-CB 3.49Å; F288-A302 VanDerWaalsContact CZ-CB 3.49Å; F288-L306 HydrophobicContact CZ-CD1 3.93Å; F288-Y370 AromaticContact CE2-CD1 3.9Å; F288-Y370 HydrophobicContact CE2-CD1 3.9Å; F288-Y370 HydrophobicContact CE2-CE1 4.26Å; F288-Y370 HydrophobicContact CE2-CG 4.08Å; F288-Y370 HydrophobicContact CZ-CG 4.32Å; F288-F376 HydrophobicContact CB-CB 4.26Å; F288-F376 HydrophobicContact CB-CD1 4.01Å; F288-F376 HydrophobicContact CB-CD2 3.86Å; F288-F376 HydrophobicContact CB-CE1 4.28Å; F288-F376 HydrophobicContact CB-CE2 4.13Å; F288-F376 HydrophobicContact CB-CG 3.79Å; F288-F376 HydrophobicContact CB-CZ 4.32Å; F288-F376 HydrophobicContact CD1-CB 3.66Å; F288-F376 HydrophobicContact CD1-CD2 4.17Å; F288-F376 HydrophobicContact CD1-CG 4.06Å; F288-F376 HydrophobicContact CD2-CB 4.34Å; F288-F376 AromaticContact CD2-CD2 3.28Å; F288-F376 HydrophobicContact CD2-CD2 3.28Å; F288-F376 AromaticContact CD2-CE2 3.67Å; F288-F376 HydrophobicContact CD2-CE2 3.67Å; F288-F376 AromaticContact CD2-CG 3.97Å; F288-F376 HydrophobicContact CD2-CG 3.97Å; F288-F376 HydrophobicContact CE1-CB 3.99Å; F288-F376 AromaticContact CE2-CD2 3.71Å; F288-F376 HydrophobicContact CE2-CD2 3.71Å; F288-F376 HydrophobicContact CE2-CE2 4.33Å; F288-F376 HydrophobicContact CG-CB 3.86Å; F288-F376 HydrophobicContact CG-CD1 4.42Å; F288-F376 AromaticContact CG-CD2 3.52Å; F288-F376 HydrophobicContact CG-CD2 3.52Å; F288-F376 HydrophobicContact CG-CE2 4.11Å; F288-F376 AromaticContact CG-CG 3.7Å; F288-F376 HydrophobicContact CG-CG 3.7Å; F288-F376 HydrophobicContact CZ-CB 4.44Å; F288-F376 HydrophobicContact CZ-CD2 4.34Å; F288-F377 HydrophobicContact CE1-CD2 4.36Å; F288-F377 AromaticContact CE1-CE2 3.66Å; F288-F377 HydrophobicContact CE1-CE2 3.66Å; F288-F377 AromaticContact CE1-CZ 3.86Å; F288-F377 HydrophobicContact CE1-CZ 3.86Å; F288-F377 HydrophobicContact CZ-CD2 4.47Å; F288-F377 AromaticContact CZ-CE2 3.61Å; F288-F377 HydrophobicContact CZ-CE2 3.61Å; F288-F377 HydrophobicContact CZ-CZ 4.07Å; F288-A433 HydrophobicContact CD1-CB 3.94Å; F288-A433 HydrophobicContact CE1-CB 3.74Å; F288-V435 HydrophobicContact CD1-CG1 4.15Å
289V98.5Very high97.3Very high2 Ų243.7 Ų43.71%0.01222%0.223CC..  trans-85.8108.4165.7179.80000107.1G287 P291 P294 V345 R434 T436G287-V289 PolarHBondContact O-N 3.23Å; V289-P291 WeakPolarHBondContact O-CD 3.41Å; V289-P294 HydrophobicContact CG1-CB 3.95Å; V289-V345 HydrophobicContact CB-CG2 4.42Å; V289-V345 HydrophobicContact CG1-CG1 4.47Å; V289-V345 HydrophobicContact CG1-CG2 3.51Å; V289-V345 HydrophobicContact CG2-CG1 3.76Å; V289-V345 HydrophobicContact CG2-CG2 4.01Å; V289-R434 HydrophobicContact CB-CB 3.91Å; V289-R434 HydrophobicContact CG2-CB 4.3Å; V289-R434 PolarHBondContact N-O 3.12Å; V289-T436 HydrophobicContact CG2-CG2 3.9Å
290D97.7Very high97.3Very high26 Ų2644.4 Ų44.414%0.13922%0.223CC..BIsolated β-bridgetrans-66.8120.1171.8-174.1-21.6000108.8K292 H293 P294 F376D290-K292 PolarHBondContact O-N 2.9Å; D290-K292 VanDerWaalsContact O-N 3.14Å; D290-K292 WeakPolarHBondContact OD1-CB 3.5Å; D290-K292 PolarHBondContact OD1-N 2.99Å; D290-H293 HydrophobicContact CB-CB 4.33Å; D290-H293 CarbonylContact O-C 3.59Å; D290-H293 PolarHBondContact O-N 3.38Å; D290-H293 IonicContact OD2-ND1 2.69Å; D290-H293 PolarHBondContact OD2-ND1 2.85Å; D290-P294 WeakPolarHBondContact O-CA 3.36Å; D290-F376 HydrophobicContact CB-CD1 4.46Å; D290-F376 HydrophobicContact CB-CE1 3.93Å
291P94Very high97.3Very high81 Ų8142.1 Ų42.153%0.52622%0.216SC..THydrogen-bonded Turntrans-58.5-26.1178.6-24.234.6000113.7V289V289-P291 WeakPolarHBondContact O-CD 3.41Å
292K96Very high97.3Very high151 Ų15141.5 Ų41.566%0.65721%0.213SC*.THydrogen-bonded Turntrans-83.5-23.7177.8-64.7-180178-179.90113D290D290-K292 PolarHBondContact O-N 2.9Å; D290-K292 VanDerWaalsContact O-N 3.14Å; D290-K292 WeakPolarHBondContact OD1-CB 3.5Å; D290-K292 PolarHBondContact OD1-N 2.99Å
293H97.2Very high97.1Very high103 Ų10341.5 Ų41.548%0.47721%0.213SC..BIsolated β-bridgetrans-14061.6-176.2-47.4100000110.5D290 D295 A296D290-H293 HydrophobicContact CB-CB 4.33Å; D290-H293 CarbonylContact O-C 3.59Å; D290-H293 PolarHBondContact O-N 3.38Å; D290-H293 IonicContact OD2-ND1 2.69Å; D290-H293 PolarHBondContact OD2-ND1 2.85Å; H293-D295 PolarHBondContact O-N 3.48Å; H293-A296 HydrophobicContact CB-CB 4.07Å; H293-A296 VanDerWaalsContact O-CB 3.27Å; H293-A296 WeakPolarHBondContact O-CB 2.76Å; H293-A296 PolarHBondContact O-N 3.36Å; H293-A296 VanDerWaalsContact O-N 3.13Å
294P97.2Very high97Very high28 Ų2840.6 Ų40.618%0.18221%0.208CC..THydrogen-bonded Turntrans-63.7-27.9-173.126.1-35.1000112.6V289 D290 K299 A344 V345V289-P294 HydrophobicContact CG1-CB 3.95Å; D290-P294 WeakPolarHBondContact O-CA 3.36Å; P294-K299 PolarHBondContact O-NZ 3.38Å; P294-A344 CarbonylContact C-O 3.54Å; P294-A344 VanDerWaalsContact C-O 3.31Å; P294-A344 HydrophobicContact CB-CB 4.25Å; P294-A344 HydrophobicContact CG-CB 4.1Å; P294-V345 HydrophobicContact CB-CG2 4.13Å; P294-V345 WeakPolarHBondContact O-CA 3.41Å
295D96.2Very high96.9Very high99 Ų9940.6 Ų40.653%0.52921%0.208SC..THydrogen-bonded Turntrans-90.13.4-179.670.6-29.6000113.7H293 K297 A344H293-D295 PolarHBondContact O-N 3.48Å; D295-K297 PolarHBondContact O-N 3.07Å; D295-A344 WeakPolarHBondContact CA-O 3.32Å; D295-A344 WeakPolarHBondContact CB-O 3.32Å; D295-A344 PolarHBondContact N-O 3.17Å
296A96.6Very high96.8Very high30 Ų3040.7 Ų40.725%0.24821%0.209CC..  trans-54.8123.7179.800000111.2H293 T298 K299H293-A296 HydrophobicContact CB-CB 4.07Å; H293-A296 VanDerWaalsContact O-CB 3.27Å; H293-A296 WeakPolarHBondContact O-CB 2.76Å; H293-A296 PolarHBondContact O-N 3.36Å; H293-A296 VanDerWaalsContact O-N 3.13Å; A296-T298 VanDerWaalsContact C-N 3.3Å; A296-T298 PolarHBondContact O-N 3.35Å; A296-K299 WeakPolarHBondContact O-CE 3.1Å; A296-K299 WeakPolarHBondContact O-CG 3.34Å; A296-K299 PolarHBondContact O-NZ 2.8Å
297K95.5Very high96.7Very high132 Ų13240.7 Ų40.757%0.57421%0.208SC*.SBendtrans-65.3-32.8177.2-68.4-170.4177.6-174.20112.5P253 T254 D295P253-K297 CarbonylContact C-O 3.25Å; P253-K297 WeakPolarHBondContact CA-O 3.28Å; P253-K297 WeakPolarHBondContact CB-O 3.49Å; T254-K297 PolarHBondContact N-O 3.36Å; D295-K297 PolarHBondContact O-N 3.07Å
298T97.4Very high96.7Very high69 Ų6940.7 Ų40.742%0.42321%0.209SC..BIsolated β-bridgetrans-104.9119171.9-53.10000109.7T254 N256 A296T254-T298 CarbonylContact O-C 3.58Å; T254-T298 VanDerWaalsContact O-CA 3.24Å; T254-T298 WeakPolarHBondContact O-CA 3.35Å; N256-T298 WeakPolarHBondContact O-CG2 3.45Å; A296-T298 VanDerWaalsContact C-N 3.3Å; A296-T298 PolarHBondContact O-N 3.35Å
299K97.8Very high96.5Very high10 Ų1041.4 Ų41.44%0.04321%0.212CC..  trans-111.6150.7-178.9-64.8-175.4-173.8-59.30110.9P253 T254 T255 P294 A296 T436 V438P253-K299 HydrophobicContact CB-CD 3.73Å; P253-K299 VanDerWaalsContact CB-CE 3.49Å; P253-K299 HydrophobicContact CB-CG 3.94Å; P253-K299 HydrophobicContact CG-CD 3.83Å; P253-K299 VanDerWaalsContact CG-CE 3.46Å; T254-K299 PolarHBondContact O-N 2.98Å; T255-K299 WeakPolarHBondContact CA-O 3.29Å; P294-K299 PolarHBondContact O-NZ 3.38Å; A296-K299 WeakPolarHBondContact O-CE 3.1Å; A296-K299 WeakPolarHBondContact O-CG 3.34Å; A296-K299 PolarHBondContact O-NZ 2.8Å; K299-T436 HydrophobicContact CD-CG2 3.7Å; K299-V438 HydrophobicContact CB-CG1 4.08Å; K299-V438 HydrophobicContact CD-CG1 3.97Å; K299-V438 HydrophobicContact CG-CG1 4.44Å
300F96.7Very high96.5Very high92 Ų9241.3 Ų41.340%0.40421%0.212SC..  trans-71.4133.3170-83.3-101.6000109.4G287 F288 A302 K374 F376G287-F300 CarbonylContact C-O 3.12Å; F288-F300 HydrophobicContact CD2-CB 4.17Å; F288-F300 PolarHBondContact N-O 2.57Å; F300-A302 PolarHBondContact O-N 2.88Å; F300-K374 HydrophobicContact CZ-CD 4.46Å; F300-F376 HydrophobicContact CB-CE2 3.46Å; F300-F376 VanDerWaalsContact CB-CE2 3.46Å; F300-F376 HydrophobicContact CB-CZ 3.57Å; F300-F376 HydrophobicContact CD1-CE2 4.22Å; F300-F376 HydrophobicContact CD1-CZ 4.44Å; F300-F376 HydrophobicContact CD2-CE2 4.15Å; F300-F376 AromaticContact CD2-CZ 3.57Å; F300-F376 HydrophobicContact CD2-CZ 3.57Å; F300-F376 HydrophobicContact CE2-CZ 4.39Å; F300-F376 AromaticContact CG-CE2 3.68Å; F300-F376 HydrophobicContact CG-CE2 3.68Å; F300-F376 AromaticContact CG-CZ 3.6Å; F300-F376 HydrophobicContact CG-CZ 3.6Å
301L97Very high96.5Very high24 Ų2440.1 Ų40.113%0.12621%0.205CC..BIsolated β-bridgetrans-64128.4171.3-174.775.2000109.3T255 H284 P303T255-L301 HydrophobicContact CG2-CB 3.98Å; T255-L301 HydrophobicContact CG2-CD1 3.99Å; H284-L301 HydrophobicContact CB-CD1 4.02Å; H284-L301 VanDerWaalsContact ND1-CD1 3.29Å; H284-L301 WeakPolarHBondContact ND1-CD1 3.47Å; L301-P303 VanDerWaalsContact O-CD 3.3Å; L301-P303 WeakPolarHBondContact O-CD 3.49Å
302A97.1Very high96.8Very high0 Ų036.2 Ų36.20%018%0.18CC..  trans-77.1110.2159.500000107.3H284 T286 F288 F300 E304 L306 L352 V435H284-A302 PolarHBondContact CE1-O 3.4Å; T286-A302 WeakPolarHBondContact O-CB 3.18Å; T286-A302 PolarHBondContact O-N 2.91Å; T286-A302 PolarHBondContact OG1-O 2.97Å; T286-A302 VanDerWaalsContact OG1-O 3.08Å; F288-A302 HydrophobicContact CD1-CB 3.92Å; F288-A302 HydrophobicContact CD2-CB 3.86Å; F288-A302 HydrophobicContact CE1-CB 3.65Å; F288-A302 HydrophobicContact CE2-CB 3.62Å; F288-A302 HydrophobicContact CG-CB 4.02Å; F288-A302 HydrophobicContact CZ-CB 3.49Å; F288-A302 VanDerWaalsContact CZ-CB 3.49Å; F300-A302 PolarHBondContact O-N 2.88Å; A302-E304 PolarHBondContact O-N 3.08Å; A302-L306 HydrophobicContact CB-CD1 4.27Å; A302-L352 HydrophobicContact CB-CD2 4.24Å; A302-V435 HydrophobicContact CB-CG1 4.17Å
303P94.5Very high96.9Very high3 Ų329.2 Ų29.22%0.01915%0.15CC..  trans-56.6138.2-169.8-22.230.4000110.9S72 L301 A305 L306 Y370S72-P303 WeakPolarHBondContact OG-CG 3.42Å; L301-P303 VanDerWaalsContact O-CD 3.3Å; L301-P303 WeakPolarHBondContact O-CD 3.49Å; P303-A305 PolarHBondContact O-N 3.42Å; P303-L306 WeakPolarHBondContact O-CB 3.43Å; P303-L306 PolarHBondContact O-N 3.38Å; P303-Y370 HydrophobicContact CG-CE2 3.81Å; P303-Y370 VanDerWaalsContact CG-OH 3.27Å; P303-Y370 WeakPolarHBondContact CG-OH 3.26Å
304E96.1Very high97Very high0 Ų024.3 Ų24.30%013%0.127CC..Hα-helixtrans-56.5-28178.9-170.5149136.100112.7S73 L139 A140 H284 A302 L306 R307 G308 R328S73-E304 PolarHBondContact OG-N 3.43Å; L139-E304 HydrophobicContact CB-CG 4.05Å; L139-E304 HydrophobicContact CD1-CB 4.31Å; L139-E304 HydrophobicContact CD1-CG 4.39Å; L139-E304 HydrophobicContact CD2-CB 4.14Å; L139-E304 HydrophobicContact CD2-CG 4.06Å; L139-E304 HydrophobicContact CG-CG 4.39Å; A140-E304 WeakPolarHBondContact CA-OE1 3.28Å; A140-E304 HydrophobicContact CB-CG 4.27Å; A140-E304 WeakPolarHBondContact CB-OE1 3.46Å; A140-E304 PolarHBondContact N-OE1 3.29Å; H284-E304 IonicContact CD2-OE2 2.7Å; H284-E304 IonicContact NE2-OE2 3.13Å; H284-E304 PolarHBondContact NE2-OE2 3.06Å; H284-E304 VanDerWaalsContact NE2-OE2 3.09Å; A302-E304 PolarHBondContact O-N 3.08Å; E304-L306 PolarHBondContact O-N 3.34Å; E304-L306 VanDerWaalsContact O-N 3.16Å; E304-R307 VanDerWaalsContact CD-NH2 3.3Å; E304-R307 VanDerWaalsContact CG-NH2 3.3Å; E304-R307 PolarHBondContact O-N 2.97Å; E304-R307 IonicContact OE2-NH2 3.99Å; E304-R307 PolarHBondContact OE2-NH2 2.87Å; E304-G308 PolarHBondContact O-N 2.83Å; E304-R328 IonicContact OE1-NE 2.57Å; E304-R328 IonicContact OE2-CZ 3.18Å; E304-R328 IonicContact OE2-NE 3.55Å; E304-R328 PolarHBondContact OE2-NE 3.04Å; E304-R328 IonicContact OE2-NH2 3.68Å; E304-R328 PolarHBondContact OE2-NH2 3.49Å
305A94.7Very high97Very high0 Ų023.6 Ų23.60%012%0.122CC..Hα-helixtrans-58.2-24.4174.200000113.6L139 P303 R307 G308 F309 I362L139-A305 HydrophobicContact CD2-CB 4.21Å; P303-A305 PolarHBondContact O-N 3.42Å; A305-R307 VanDerWaalsContact C-N 3.32Å; A305-G308 CarbonylContact O-C 3.31Å; A305-G308 PolarHBondContact O-N 3.43Å; A305-F309 HydrophobicContact CB-CD2 4.24Å; A305-F309 HydrophobicContact CB-CE2 4.1Å; A305-F309 WeakPolarHBondContact O-CB 3.3Å; A305-F309 WeakPolarHBondContact O-CD2 3.37Å; A305-F309 PolarHBondContact O-N 3.03Å; A305-I362 HydrophobicContact CB-CD1 3.65Å
306L96.5Very high97.1Very high1 Ų120.8 Ų20.81%0.00511%0.105CC..Hα-helixtrans-61.2-44.6173.5-74.3164.4000110.3F288 A302 P303 E304 G311 L352 V354 I358 I362 F367 F377F288-L306 HydrophobicContact CZ-CD1 3.93Å; A302-L306 HydrophobicContact CB-CD1 4.27Å; P303-L306 WeakPolarHBondContact O-CB 3.43Å; P303-L306 PolarHBondContact O-N 3.38Å; E304-L306 PolarHBondContact O-N 3.34Å; E304-L306 VanDerWaalsContact O-N 3.16Å; L306-G311 WeakPolarHBondContact O-CA 3.18Å; L306-G311 PolarHBondContact O-N 3.07Å; L306-L352 HydrophobicContact CB-CD2 4.18Å; L306-L352 HydrophobicContact CD1-CD2 3.85Å; L306-V354 HydrophobicContact CD2-CG1 4.23Å; L306-I358 HydrophobicContact CD2-CG2 4.28Å; L306-I362 HydrophobicContact CD2-CD1 4.03Å; L306-I362 HydrophobicContact CD2-CG1 3.76Å; L306-I362 HydrophobicContact CG-CD1 4.07Å; L306-I362 HydrophobicContact CG-CG1 4.37Å; L306-F367 HydrophobicContact CD2-CD2 4.43Å; L306-F377 HydrophobicContact CD1-CE2 4.43Å; L306-F377 HydrophobicContact CD1-CZ 4.13Å; L306-F377 HydrophobicContact CD2-CZ 4.43Å
307R98Very high97.2Very high1 Ų122 Ų220%0.00411%0.112CC..Hα-helixtrans-71.4-39.5171.6-65.2-178.5-71.5113.8-4.3111.3A140 E304 A305 F309 G310 E324 L325 L352A140-R307 VanDerWaalsContact CB-NH1 3.34Å; E304-R307 VanDerWaalsContact CD-NH2 3.3Å; E304-R307 VanDerWaalsContact CG-NH2 3.3Å; E304-R307 PolarHBondContact O-N 2.97Å; E304-R307 IonicContact OE2-NH2 3.99Å; E304-R307 PolarHBondContact OE2-NH2 2.87Å; A305-R307 VanDerWaalsContact C-N 3.32Å; R307-F309 PolarHBondContact O-N 2.71Å; R307-G310 WeakPolarHBondContact O-CA 3.39Å; R307-G310 PolarHBondContact O-N 3.45Å; R307-E324 HydrophobicContact CB-CB 4.34Å; R307-E324 WeakPolarHBondContact CD-O 3.43Å; R307-E324 HydrophobicContact CG-CB 4.29Å; R307-E324 PolarHBondContact NH1-O 3.49Å; R307-L325 HydrophobicContact CB-CD2 4.21Å; R307-L352 HydrophobicContact CG-CD1 4.36Å
308G96.5Very high97.3Very high1 Ų115.8 Ų15.81%0.019%0.085CC..Hα-helixtrans-56.8-32.1176.500000114.5I138 E304 A305I138-G308 WeakPolarHBondContact O-CA 3.32Å; E304-G308 PolarHBondContact O-N 2.83Å; A305-G308 CarbonylContact O-C 3.31Å; A305-G308 PolarHBondContact O-N 3.43Å
309F96.2Very high97.3Very high16 Ų1619.5 Ų19.57%0.079%0.091CC..THydrogen-bonded Turntrans-92.33.5174-68.2-53.7000114Q135 V137 A305 R307 I358 K361 I362Q135-F309 HydrophobicContact CG-CZ 4.41Å; V137-F309 HydrophobicContact CB-CE1 3.89Å; V137-F309 HydrophobicContact CB-CZ 3.82Å; V137-F309 HydrophobicContact CG2-CD1 3.76Å; V137-F309 HydrophobicContact CG2-CD2 4.35Å; V137-F309 HydrophobicContact CG2-CE1 3.47Å; V137-F309 VanDerWaalsContact CG2-CE1 3.47Å; V137-F309 HydrophobicContact CG2-CE2 4.1Å; V137-F309 HydrophobicContact CG2-CG 4.2Å; V137-F309 HydrophobicContact CG2-CZ 3.65Å; A305-F309 HydrophobicContact CB-CD2 4.24Å; A305-F309 HydrophobicContact CB-CE2 4.1Å; A305-F309 WeakPolarHBondContact O-CB 3.3Å; A305-F309 WeakPolarHBondContact O-CD2 3.37Å; A305-F309 PolarHBondContact O-N 3.03Å; R307-F309 PolarHBondContact O-N 2.71Å; F309-I358 HydrophobicContact CB-CG2 4.15Å; F309-I358 WeakPolarHBondContact O-CG1 3.43Å; F309-K361 HydrophobicContact CB-CB 4.24Å; F309-K361 HydrophobicContact CB-CD 4.32Å; F309-K361 HydrophobicContact CD1-CB 3.82Å; F309-K361 HydrophobicContact CD1-CD 3.93Å; F309-K361 HydrophobicContact CD1-CG 4.36Å; F309-K361 HydrophobicContact CD2-CB 3.96Å; F309-K361 HydrophobicContact CE1-CB 4.1Å; F309-K361 HydrophobicContact CE2-CB 4.24Å; F309-K361 HydrophobicContact CG-CB 3.75Å; F309-K361 HydrophobicContact CG-CD 4.3Å; F309-K361 HydrophobicContact CZ-CB 4.3Å; F309-I362 HydrophobicContact CD2-CD1 3.56Å; F309-I362 HydrophobicContact CD2-CG1 3.81Å; F309-I362 HydrophobicContact CE2-CD1 3.87Å; F309-I362 HydrophobicContact CE2-CG1 4.3Å
310G97.5Very high97.4Very high1 Ų119.8 Ų19.81%0.019%0.092CC..THydrogen-bonded Turntrans110.310.1170.800000115.7R307 I312 F424R307-G310 WeakPolarHBondContact O-CA 3.39Å; R307-G310 PolarHBondContact O-N 3.45Å; G310-I312 PolarHBondContact O-N 3.3Å; G310-F424 WeakPolarHBondContact O-CE2 3.49Å; G310-F424 WeakPolarHBondContact O-CZ 3.43Å
311G98.5Very high97.4Very high0 Ų016.1 Ų16.10%08%0.076CC..  trans-58.8134.2170.700000111.5L306 V353L306-G311 WeakPolarHBondContact O-CA 3.18Å; L306-G311 PolarHBondContact O-N 3.07Å; G311-V353 WeakPolarHBondContact CA-O 3.38Å
312I98.7Very high97.5Very high0 Ų017 Ų170%08%0.079CC..EExtended strand (participates in β ladder)trans-104.2153-176.661.4177.5000111.4G310 L314 E324 L352 V353 L401 Y404 F424G310-I312 PolarHBondContact O-N 3.3Å; I312-L314 HydrophobicContact CD1-CD2 4.06Å; I312-L314 HydrophobicContact CG1-CD2 4.37Å; I312-E324 WeakPolarHBondContact CA-OE1 3.35Å; I312-E324 WeakPolarHBondContact CB-OE1 3.3Å; I312-L352 WeakPolarHBondContact O-CA 3.32Å; I312-V353 HydrophobicContact CG1-CB 3.93Å; I312-V353 PolarHBondContact N-O 3.32Å; I312-V353 PolarHBondContact O-N 2.82Å; I312-L401 HydrophobicContact CD1-CD2 3.9Å; I312-Y404 HydrophobicContact CG2-CD2 3.7Å; I312-Y404 HydrophobicContact CG2-CE2 3.49Å; I312-Y404 VanDerWaalsContact CG2-CE2 3.49Å; I312-F424 HydrophobicContact CD1-CD2 4.35Å; I312-F424 HydrophobicContact CD1-CE2 4.16Å; I312-F424 HydrophobicContact CD1-CZ 4.35Å; I312-F424 HydrophobicContact CG1-CE2 4.25Å; I312-F424 HydrophobicContact CG1-CZ 4.12Å; I312-F424 HydrophobicContact CG2-CE2 3.79Å; I312-F424 HydrophobicContact CG2-CZ 4.26Å
313L98.9Very high97.5Very high4 Ų418.1 Ų18.12%0.0219%0.085CC..EExtended strand (participates in β ladder)trans-108.3127.3175.7-66.7177.5000110.1T286 R320 F321 E324 V331 I335 A350 F351 L352 V435T286-L313 HydrophobicContact CG2-CD1 4.4Å; T286-L313 HydrophobicContact CG2-CD2 4.1Å; L313-R320 WeakPolarHBondContact O-CA 3.35Å; L313-F321 HydrophobicContact CB-CE1 4.01Å; L313-F321 HydrophobicContact CB-CZ 3.81Å; L313-F321 HydrophobicContact CD1-CZ 4.4Å; L313-E324 HydrophobicContact CB-CG 4.17Å; L313-E324 HydrophobicContact CD1-CG 4.49Å; L313-E324 HydrophobicContact CG-CG 4.08Å; L313-E324 PolarHBondContact N-OE1 3.23Å; L313-V331 HydrophobicContact CD1-CG1 3.68Å; L313-I335 HydrophobicContact CD1-CD1 4.34Å; L313-A350 HydrophobicContact CD2-CB 4.47Å; L313-F351 CarbonylContact C-O 3.44Å; L313-F351 WeakPolarHBondContact CA-O 3.46Å; L313-L352 HydrophobicContact CD2-CB 4.02Å; L313-L352 HydrophobicContact CD2-CD1 3.99Å; L313-V435 HydrophobicContact CD2-CG2 3.92Å
314L98.8Very high97.7Very high0 Ų018 Ų180%09%0.085CC..EExtended strand (participates in β ladder)trans-116.4143.3178.2-51.7-174.9000110.8I312 R319 R320 F351 V353 L386 M390 I397 T400I312-L314 HydrophobicContact CD1-CD2 4.06Å; I312-L314 HydrophobicContact CG1-CD2 4.37Å; L314-R319 WeakPolarHBondContact CA-O 3.29Å; L314-R320 HydrophobicContact CD2-CG 3.76Å; L314-F351 HydrophobicContact CB-CB 4.34Å; L314-F351 PolarHBondContact N-O 2.98Å; L314-F351 PolarHBondContact O-N 3.21Å; L314-V353 HydrophobicContact CD1-CG2 3.72Å; L314-V353 HydrophobicContact CG-CG2 4.07Å; L314-L386 HydrophobicContact CD1-CD2 4.49Å; L314-M390 HydrophobicContact CB-CE 3.85Å; L314-M390 HydrophobicContact CD1-CE 4.1Å; L314-M390 HydrophobicContact CD1-SD 4.01Å; L314-I397 HydrophobicContact CD1-CD1 4Å; L314-T400 HydrophobicContact CD2-CG2 3.64Å
315N98.7Very high97.8Very high13 Ų1318.7 Ų18.77%0.079%0.088CC..  trans-87.4-175.1169.267.913.3000111.7S317 G318 R319 F321 F338 M390N315-S317 PolarHBondContact O-N 2.7Å; N315-S317 VanDerWaalsContact O-N 3.11Å; N315-S317 WeakPolarHBondContact OD1-CA 3.25Å; N315-S317 WeakPolarHBondContact OD1-CB 3.44Å; N315-S317 PolarHBondContact OD1-N 3.41Å; N315-G318 PolarHBondContact O-N 3.45Å; N315-G318 PolarHBondContact OD1-N 3.05Å; N315-R319 PolarHBondContact N-O 2.77Å; N315-R319 PolarHBondContact OD1-N 3.24Å; N315-R319 PolarHBondContact OD1-O 3.49Å; N315-F321 HydrophobicContact CB-CD1 3.9Å; N315-F321 HydrophobicContact CB-CE1 4.2Å; N315-F338 VanDerWaalsContact CB-O 3.25Å; N315-F338 WeakPolarHBondContact CB-O 3.45Å; N315-F338 PolarHBondContact ND2-O 2.9Å; N315-M390 WeakPolarHBondContact O-CE 3.45Å
316Q97.8Very high97.9Very high40 Ų4019.5 Ų19.519%0.18710%0.095CC..THydrogen-bonded Turntrans-69.1-3.5-179.7-68.576.18.700114.1C339 K340 V349 F351 V392Q316-C339 VanDerWaalsContact OE1-CA 3.28Å; Q316-K340 HydrophobicContact CB-CD 3.94Å; Q316-K340 HydrophobicContact CB-CG 4.03Å; Q316-K340 HydrophobicContact CG-CB 3.94Å; Q316-K340 HydrophobicContact CG-CD 3.83Å; Q316-K340 HydrophobicContact CG-CG 3.75Å; Q316-V349 PolarHBondContact NE2-O 2.86Å; Q316-F351 HydrophobicContact CG-CE2 4.23Å; Q316-V392 WeakPolarHBondContact O-CG1 3.22Å
317S97.8Very high97.9Very high56 Ų5621 Ų2139%0.39210%0.102SC..THydrogen-bonded Turntrans-101.27.5170-57.10000112.1N315 R319N315-S317 PolarHBondContact O-N 2.7Å; N315-S317 VanDerWaalsContact O-N 3.11Å; N315-S317 WeakPolarHBondContact OD1-CA 3.25Å; N315-S317 WeakPolarHBondContact OD1-CB 3.44Å; N315-S317 PolarHBondContact OD1-N 3.41Å; S317-R319 VanDerWaalsContact C-N 3.26Å; S317-R319 PolarHBondContact O-N 2.76Å
318G98.3Very high97.9Very high0 Ų021.3 Ų21.30%010%0.103CC..SBendtrans7511.7-179.300000114.4N315 T400N315-G318 PolarHBondContact O-N 3.45Å; N315-G318 PolarHBondContact OD1-N 3.05Å; G318-T400 PolarHBondContact O-OG1 3.09Å
319R98.2Very high97.8Very high147 Ų14722.8 Ų22.856%0.55511%0.111SC*.  trans-106.1145.8-174.8-62-169.4-63.8-146.6-0.4112.1L314 N315 S317L314-R319 WeakPolarHBondContact CA-O 3.29Å; N315-R319 PolarHBondContact N-O 2.77Å; N315-R319 PolarHBondContact OD1-N 3.24Å; N315-R319 PolarHBondContact OD1-O 3.49Å; S317-R319 VanDerWaalsContact C-N 3.26Å; S317-R319 PolarHBondContact O-N 2.76Å
320R98.4Very high97.9Very high17 Ų1724.6 Ų24.66%0.06412%0.123CC..  trans-63.1156162-67.2176.169.1-134.2-5.2109.8L313 L314 E324 T400 D413 Y415L313-R320 WeakPolarHBondContact O-CA 3.35Å; L314-R320 HydrophobicContact CD2-CG 3.76Å; R320-E324 IonicContact CZ-OE1 3.47Å; R320-E324 IonicContact CZ-OE2 2.78Å; R320-E324 IonicContact NE-OE1 2.7Å; R320-E324 PolarHBondContact NE-OE1 2.71Å; R320-E324 IonicContact NE-OE2 3.66Å; R320-E324 IonicContact NH2-OE1 3.3Å; R320-E324 PolarHBondContact NH2-OE1 3.4Å; R320-E324 IonicContact NH2-OE2 3.9Å; R320-E324 PolarHBondContact NH2-OE2 2.98Å; R320-T400 HydrophobicContact CG-CG2 3.85Å; R320-D413 IonicContact CZ-OD2 2.89Å; R320-D413 VanDerWaalsContact CZ-OD2 3.3Å; R320-D413 IonicContact NH1-OD2 2.63Å; R320-D413 PolarHBondContact NH1-OD2 3.21Å; R320-D413 IonicContact NH2-OD2 2.76Å; R320-D413 PolarHBondContact NH2-OD2 2.98Å; R320-Y415 HydrophobicContact CB-CE2 3.91Å; R320-Y415 PolarHBondContact O-OH 3.24Å
321F98.1Very high98Very high15 Ų1524.6 Ų24.67%0.06612%0.123CC..  trans-146-1.6-17555.8-97.6000114L313 N315 A334 I335 F338 A350L313-F321 HydrophobicContact CB-CE1 4.01Å; L313-F321 HydrophobicContact CB-CZ 3.81Å; L313-F321 HydrophobicContact CD1-CZ 4.4Å; N315-F321 HydrophobicContact CB-CD1 3.9Å; N315-F321 HydrophobicContact CB-CE1 4.2Å; F321-A334 HydrophobicContact CD2-CB 3.82Å; F321-A334 HydrophobicContact CE2-CB 4.03Å; F321-I335 HydrophobicContact CE2-CG1 3.84Å; F321-I335 HydrophobicContact CZ-CG1 3.8Å; F321-F338 HydrophobicContact CB-CB 3.81Å; F321-F338 HydrophobicContact CB-CD2 3.91Å; F321-F338 HydrophobicContact CB-CG 3.95Å; F321-F338 HydrophobicContact CD2-CB 4.21Å; F321-F338 HydrophobicContact CD2-CD2 4.14Å; F321-F338 HydrophobicContact CG-CB 3.95Å; F321-F338 HydrophobicContact CG-CD2 4.36Å; F321-F338 HydrophobicContact CG-CG 4.48Å; F321-A350 HydrophobicContact CE1-CB 4.32Å; F321-A350 HydrophobicContact CZ-CB 4.05Å
322E98Very high97.9Very high42 Ų4225 Ų2520%0.19613%0.126CC..SBendtrans-164.9161.8178.8-172.549.1-88.700109.4E324 A326 T330 V331 A334E322-E324 PolarHBondContact O-N 3.29Å; E322-A326 HydrophobicContact CG-CB 4.29Å; E322-T330 HydrophobicContact CG-CG2 4.46Å; E322-T330 WeakPolarHBondContact OE2-CG2 3.17Å; E322-V331 HydrophobicContact CG-CG2 4.25Å; E322-A334 HydrophobicContact CB-CB 3.81Å; E322-A334 HydrophobicContact CG-CB 4.02Å
323N98.2Very high97.9Very high23 Ų2327.5 Ų27.512%0.12315%0.146CC..  trans-66.9115.4161.9172.47.9000109.5L325 A326 K417N323-L325 PolarHBondContact O-N 3.41Å; N323-L325 PolarHBondContact OD1-N 2.64Å; N323-A326 HydrophobicContact CB-CB 4.27Å; N323-A326 VanDerWaalsContact O-CB 3.25Å; N323-A326 WeakPolarHBondContact O-CB 3.32Å; N323-A326 PolarHBondContact O-N 3.11Å; N323-K417 HydrophobicContact CB-CB 4.06Å; N323-K417 WeakPolarHBondContact OD1-CG 3.45Å
324E98.2Very high97.9Very high1 Ų127.5 Ų27.51%0.00515%0.147CC..THydrogen-bonded Turntrans-65.4-8-177.8-6087.4169.200113.6R307 I312 L313 R320 E322 K417R307-E324 HydrophobicContact CB-CB 4.34Å; R307-E324 WeakPolarHBondContact CD-O 3.43Å; R307-E324 HydrophobicContact CG-CB 4.29Å; R307-E324 PolarHBondContact NH1-O 3.49Å; I312-E324 WeakPolarHBondContact CA-OE1 3.35Å; I312-E324 WeakPolarHBondContact CB-OE1 3.3Å; L313-E324 HydrophobicContact CB-CG 4.17Å; L313-E324 HydrophobicContact CD1-CG 4.49Å; L313-E324 HydrophobicContact CG-CG 4.08Å; L313-E324 PolarHBondContact N-OE1 3.23Å; R320-E324 IonicContact CZ-OE1 3.47Å; R320-E324 IonicContact CZ-OE2 2.78Å; R320-E324 IonicContact NE-OE1 2.7Å; R320-E324 PolarHBondContact NE-OE1 2.71Å; R320-E324 IonicContact NE-OE2 3.66Å; R320-E324 IonicContact NH2-OE1 3.3Å; R320-E324 PolarHBondContact NH2-OE1 3.4Å; R320-E324 IonicContact NH2-OE2 3.9Å; R320-E324 PolarHBondContact NH2-OE2 2.98Å; E322-E324 PolarHBondContact O-N 3.29Å; E324-K417 IonicContact OE2-NZ 3.55Å
325L97.5Very high97.9Very high15 Ų1527.5 Ų27.58%0.07915%0.147CC..THydrogen-bonded Turntrans-110.512.4172.8-61.5179.5000113.5I138 A140 G141 R307 N323 V419I138-L325 HydrophobicContact CG2-CD1 4.39Å; A140-L325 CarbonylContact C-O 3.57Å; A140-L325 VanDerWaalsContact CA-O 3.31Å; A140-L325 WeakPolarHBondContact CA-O 3.3Å; A140-L325 HydrophobicContact CB-CD2 4.34Å; G141-L325 PolarHBondContact N-O 3.44Å; R307-L325 HydrophobicContact CB-CD2 4.21Å; N323-L325 PolarHBondContact O-N 3.41Å; N323-L325 PolarHBondContact OD1-N 2.64Å; L325-V419 HydrophobicContact CD1-CB 3.97Å; L325-V419 HydrophobicContact CD1-CG1 3.89Å
326A97.3Very high97.8Very high17 Ų1730.6 Ų30.614%0.1417%0.166CC..SBendtrans-63.516916500000111.3A140 E322 N323 T330 V331A140-A326 WeakPolarHBondContact CB-O 3.46Å; E322-A326 HydrophobicContact CG-CB 4.29Å; N323-A326 HydrophobicContact CB-CB 4.27Å; N323-A326 VanDerWaalsContact O-CB 3.25Å; N323-A326 WeakPolarHBondContact O-CB 3.32Å; N323-A326 PolarHBondContact O-N 3.11Å; A326-T330 HydrophobicContact CB-CG2 4.04Å; A326-V331 HydrophobicContact CB-CG2 3.94Å
327Q96.1Very high97.8Very high32 Ų3233 Ų3315%0.1519%0.188CC..  trans-59.6153.2179.3-64.1-177.40.200111.5K101 D329 T330 V331K101-Q327 VanDerWaalsContact C-NE2 3.32Å; K101-Q327 PolarHBondContact O-NE2 2.94Å; Q327-D329 VanDerWaalsContact C-N 3.31Å; Q327-D329 WeakPolarHBondContact CB-OD1 3.31Å; Q327-D329 PolarHBondContact O-N 2.92Å; Q327-T330 WeakPolarHBondContact O-CB 3.4Å; Q327-T330 PolarHBondContact O-N 3.21Å; Q327-T330 VanDerWaalsContact O-N 3.08Å; Q327-V331 WeakPolarHBondContact O-CG2 3.48Å; Q327-V331 PolarHBondContact O-N 3.36Å
328R97.4Very high97.9Very high7 Ų735.9 Ų35.93%0.02619%0.193CC..Hα-helixtrans-66.3-36.3-169.4-69.9164.3164.9177.9-11.1111.9Q282 H284 E304 T330 T332 D479 R480Q282-R328 VanDerWaalsContact CD-NH1 3.33Å; H284-R328 PolarHBondContact CD2-NE 3Å; H284-R328 PolarHBondContact CD2-NH2 3.44Å; E304-R328 IonicContact OE1-NE 2.57Å; E304-R328 IonicContact OE2-CZ 3.18Å; E304-R328 IonicContact OE2-NE 3.55Å; E304-R328 PolarHBondContact OE2-NE 3.04Å; E304-R328 IonicContact OE2-NH2 3.68Å; E304-R328 PolarHBondContact OE2-NH2 3.49Å; R328-T330 VanDerWaalsContact C-N 3.35Å; R328-T332 WeakPolarHBondContact O-CB 3.22Å; R328-T332 PolarHBondContact O-N 3.11Å; R328-T332 PolarHBondContact O-OG1 3.25Å; R328-D479 WeakPolarHBondContact CB-OD2 3.48Å; R328-R480 PolarHBondContact NH1-O 3.48Å
329D96.3Very high97.9Very high33 Ų3336.3 Ų36.318%0.17620%0.196CC..Hα-helixtrans-59-44.5171.166-22.4000112Q104 Q327 T332 A333 Y478 D479Q104-D329 PolarHBondContact NE2-OD2 3.38Å; Q104-D329 VanDerWaalsContact NE2-OD2 3.1Å; Q327-D329 VanDerWaalsContact C-N 3.31Å; Q327-D329 WeakPolarHBondContact CB-OD1 3.31Å; Q327-D329 PolarHBondContact O-N 2.92Å; D329-T332 PolarHBondContact O-N 2.96Å; D329-A333 WeakPolarHBondContact O-CB 3.14Å; D329-A333 PolarHBondContact O-N 3.02Å; D329-Y478 HydrophobicContact CB-CE1 4.08Å; D329-Y478 WeakPolarHBondContact OD2-CE1 3.25Å; D329-D479 PolarHBondContact N-OD2 2.95Å
330T97.5Very high97.9Very high54 Ų5436.1 Ų36.133%0.33120%0.199SC..Hα-helixtrans-63.3-51.5178.6-55.60000110.6E322 A326 Q327 R328 T332 A333 A334E322-T330 HydrophobicContact CG-CG2 4.46Å; E322-T330 WeakPolarHBondContact OE2-CG2 3.17Å; A326-T330 HydrophobicContact CB-CG2 4.04Å; Q327-T330 WeakPolarHBondContact O-CB 3.4Å; Q327-T330 PolarHBondContact O-N 3.21Å; Q327-T330 VanDerWaalsContact O-N 3.08Å; R328-T330 VanDerWaalsContact C-N 3.35Å; T330-T332 VanDerWaalsContact C-N 3.3Å; T330-T332 PolarHBondContact O-N 3.08Å; T330-A333 PolarHBondContact O-N 2.96Å; T330-A334 WeakPolarHBondContact O-CB 3.43Å; T330-A334 PolarHBondContact O-N 3.43Å
331V98.4Very high97.8Very high0 Ų042.9 Ų42.90%023%0.225CC..Hα-helixtrans-64.3-36.9178.6-176.40000111P285 L313 E322 A326 Q327 A334 I335P285-V331 HydrophobicContact CB-CB 3.93Å; P285-V331 HydrophobicContact CB-CG1 3.55Å; P285-V331 HydrophobicContact CG-CB 4.07Å; P285-V331 HydrophobicContact CG-CG1 3.93Å; L313-V331 HydrophobicContact CD1-CG1 3.68Å; E322-V331 HydrophobicContact CG-CG2 4.25Å; A326-V331 HydrophobicContact CB-CG2 3.94Å; Q327-V331 WeakPolarHBondContact O-CG2 3.48Å; Q327-V331 PolarHBondContact O-N 3.36Å; V331-A334 PolarHBondContact O-N 3.37Å; V331-I335 HydrophobicContact CG1-CD1 4.32Å; V331-I335 WeakPolarHBondContact O-CG1 3.16Å; V331-I335 PolarHBondContact O-N 2.87Å
332T98.1Very high97.8Very high9 Ų944.2 Ų44.26%0.05523%0.233CC..Hα-helixtrans-65.8-43.8176.2-64.80000112L283 P285 R328 D329 T330 A334 I335 T336 P437L283-T332 HydrophobicContact CB-CG2 3.8Å; L283-T332 HydrophobicContact CD1-CG2 3.75Å; L283-T332 HydrophobicContact CG-CG2 4.44Å; L283-T332 PolarHBondContact O-OG1 3.09Å; P285-T332 WeakPolarHBondContact CA-OG1 3.42Å; R328-T332 WeakPolarHBondContact O-CB 3.22Å; R328-T332 PolarHBondContact O-N 3.11Å; R328-T332 PolarHBondContact O-OG1 3.25Å; D329-T332 PolarHBondContact O-N 2.96Å; T330-T332 VanDerWaalsContact C-N 3.3Å; T330-T332 PolarHBondContact O-N 3.08Å; T332-A334 VanDerWaalsContact C-N 3.31Å; T332-A334 PolarHBondContact O-N 2.93Å; T332-I335 PolarHBondContact O-N 3.4Å; T332-T336 PolarHBondContact O-N 3.37Å; T332-T336 PolarHBondContact O-OG1 2.88Å; T332-P437 HydrophobicContact CG2-CB 3.7Å; T332-P437 HydrophobicContact CG2-CG 3.84Å
333A97.9Very high97.7Very high52 Ų5247 Ų4743%0.4325%0.254SS..Hα-helixtrans-61.8-42174.500000110.7D329 T330 I335 T336 S337D329-A333 WeakPolarHBondContact O-CB 3.14Å; D329-A333 PolarHBondContact O-N 3.02Å; T330-A333 PolarHBondContact O-N 2.96Å; A333-I335 PolarHBondContact O-N 3.49Å; A333-T336 WeakPolarHBondContact O-CB 3.32Å; A333-T336 PolarHBondContact O-N 3.36Å; A333-T336 VanDerWaalsContact O-N 3.15Å; A333-S337 PolarHBondContact O-N 2.92Å; A333-S337 PolarHBondContact O-OG 2.96Å; A333-S337 VanDerWaalsContact O-OG 3.12Å
334A98.7Very high97.6Very high5 Ų548.1 Ų48.14%0.04127%0.267CS..Hα-helixtrans-63.8-40.6176.900000112.4F321 E322 T330 V331 T332 T336 S337 F338F321-A334 HydrophobicContact CD2-CB 3.82Å; F321-A334 HydrophobicContact CE2-CB 4.03Å; E322-A334 HydrophobicContact CB-CB 3.81Å; E322-A334 HydrophobicContact CG-CB 4.02Å; T330-A334 WeakPolarHBondContact O-CB 3.43Å; T330-A334 PolarHBondContact O-N 3.43Å; V331-A334 PolarHBondContact O-N 3.37Å; T332-A334 VanDerWaalsContact C-N 3.31Å; T332-A334 PolarHBondContact O-N 2.93Å; A334-T336 VanDerWaalsContact C-N 3.3Å; A334-T336 PolarHBondContact O-N 2.87Å; A334-S337 PolarHBondContact O-N 3.5Å; A334-F338 HydrophobicContact CB-CD2 4.13Å; A334-F338 HydrophobicContact CB-CE2 4.44Å; A334-F338 WeakPolarHBondContact O-CB 3.48Å; A334-F338 VanDerWaalsContact O-CD2 3.26Å; A334-F338 WeakPolarHBondContact O-CD2 3.36Å; A334-F338 PolarHBondContact O-N 3.25Å
335I98.8Very high97.5Very high0 Ų048.3 Ų48.30%027%0.268CS..Hα-helixtrans-61.1-42.7172.5-67.9167.2000110.5P285 L313 F321 V331 T332 A333 S337 C339 A350 P437P285-I335 HydrophobicContact CB-CD1 3.69Å; P285-I335 WeakPolarHBondContact O-CD1 3.43Å; L313-I335 HydrophobicContact CD1-CD1 4.34Å; F321-I335 HydrophobicContact CE2-CG1 3.84Å; F321-I335 HydrophobicContact CZ-CG1 3.8Å; V331-I335 HydrophobicContact CG1-CD1 4.32Å; V331-I335 WeakPolarHBondContact O-CG1 3.16Å; V331-I335 PolarHBondContact O-N 2.87Å; T332-I335 PolarHBondContact O-N 3.4Å; A333-I335 PolarHBondContact O-N 3.49Å; I335-S337 VanDerWaalsContact C-N 3.32Å; I335-S337 PolarHBondContact O-N 3.48Å; I335-C339 HydrophobicContact CG2-CB 4.14Å; I335-C339 WeakPolarHBondContact O-CB 3.21Å; I335-C339 PolarHBondContact O-N 2.88Å; I335-A350 HydrophobicContact CD1-CB 4.39Å; I335-A350 HydrophobicContact CG1-CB 4.14Å; I335-A350 HydrophobicContact CG2-CB 4.39Å; I335-P437 HydrophobicContact CB-CG 4.26Å; I335-P437 HydrophobicContact CD1-CG 4.47Å; I335-P437 HydrophobicContact CG2-CG 3.99Å
336T97.2Very high97.4Very high78 Ų7853.5 Ų53.548%0.47929%0.29SS..Hα-helixtrans-62.9-40.3179.1-54.20000111.6T332 A333 A334T332-T336 PolarHBondContact O-N 3.37Å; T332-T336 PolarHBondContact O-OG1 2.88Å; A333-T336 WeakPolarHBondContact O-CB 3.32Å; A333-T336 PolarHBondContact O-N 3.36Å; A333-T336 VanDerWaalsContact O-N 3.15Å; A334-T336 VanDerWaalsContact C-N 3.3Å; A334-T336 PolarHBondContact O-N 2.87Å
337S98.2Very high97.4Very high91 Ų9153 Ų5364%0.63629%0.287SS*.Hα-helixtrans-79.8-37.3-177-62.40000114.2A333 A334 I335A333-S337 PolarHBondContact O-N 2.92Å; A333-S337 PolarHBondContact O-OG 2.96Å; A333-S337 VanDerWaalsContact O-OG 3.12Å; A334-S337 PolarHBondContact O-N 3.5Å; I335-S337 VanDerWaalsContact C-N 3.32Å; I335-S337 PolarHBondContact O-N 3.48Å
338F98.4Very high97.5Very high116 Ų11652.1 Ų52.151%0.50928%0.284SS..Hα-helixtrans-111.1-6.9-168.1-61-64.7000114.6N315 F321 A334N315-F338 VanDerWaalsContact CB-O 3.25Å; N315-F338 WeakPolarHBondContact CB-O 3.45Å; N315-F338 PolarHBondContact ND2-O 2.9Å; F321-F338 HydrophobicContact CB-CB 3.81Å; F321-F338 HydrophobicContact CB-CD2 3.91Å; F321-F338 HydrophobicContact CB-CG 3.95Å; F321-F338 HydrophobicContact CD2-CB 4.21Å; F321-F338 HydrophobicContact CD2-CD2 4.14Å; F321-F338 HydrophobicContact CG-CB 3.95Å; F321-F338 HydrophobicContact CG-CD2 4.36Å; F321-F338 HydrophobicContact CG-CG 4.48Å; A334-F338 HydrophobicContact CB-CD2 4.13Å; A334-F338 HydrophobicContact CB-CE2 4.44Å; A334-F338 WeakPolarHBondContact O-CB 3.48Å; A334-F338 VanDerWaalsContact O-CD2 3.26Å; A334-F338 WeakPolarHBondContact O-CD2 3.36Å; A334-F338 PolarHBondContact O-N 3.25Å
339C98.6Very high97.5Very high9 Ų951.9 Ų51.96%0.06128%0.283CS..SBendtrans-112.2145178.1-57.20000111.8Q316 I335 V349Q316-C339 VanDerWaalsContact OE1-CA 3.28Å; I335-C339 HydrophobicContact CG2-CB 4.14Å; I335-C339 WeakPolarHBondContact O-CB 3.21Å; I335-C339 PolarHBondContact O-N 2.88Å; C339-V349 VanDerWaalsContact CB-O 3.31Å; C339-V349 WeakPolarHBondContact CB-O 3.41Å
340K97.8Very high97.6Very high142 Ų14250.3 Ų50.362%0.61728%0.275SS*.  trans-68.9140.4178.1-60.5-171.7-175.8175.20110.9Q316 S348 V349Q316-K340 HydrophobicContact CB-CD 3.94Å; Q316-K340 HydrophobicContact CB-CG 4.03Å; Q316-K340 HydrophobicContact CG-CB 3.94Å; Q316-K340 HydrophobicContact CG-CD 3.83Å; Q316-K340 HydrophobicContact CG-CG 3.75Å; K340-S348 WeakPolarHBondContact O-CA 3.38Å; K340-V349 PolarHBondContact O-N 3.32Å; K340-V349 VanDerWaalsContact O-N 3.07Å
341W97.8Very high97.7Very high160 Ų16048.9 Ų48.961%0.60626%0.264SS*.EExtended strand (participates in β ladder)trans-65.8128.7166.5-175.5-92.3000110.4K346 G347W341-K346 WeakPolarHBondContact CH2-O 3.14Å; W341-K346 HydrophobicContact CZ2-CB 4.19Å; W341-K346 WeakPolarHBondContact CZ2-O 3.44Å; W341-G347 VanDerWaalsContact CE3-C 3.5Å; W341-G347 VanDerWaalsContact CZ3-CA 3.42Å
342D97.1Very high97.7Very high42 Ų4248.9 Ų48.923%0.22526%0.264CS..EExtended strand (participates in β ladder)trans-105.5115.5172.1-173-41000109.7A344 V345 K346 G347 V349 R434D342-A344 VanDerWaalsContact C-N 3.26Å; D342-A344 PolarHBondContact O-N 3.34Å; D342-A344 WeakPolarHBondContact OD1-CA 3.38Å; D342-A344 VanDerWaalsContact OD1-CB 3.3Å; D342-A344 WeakPolarHBondContact OD1-CB 3.36Å; D342-A344 PolarHBondContact OD1-N 3.28Å; D342-V345 HydrophobicContact CB-CB 4.12Å; D342-V345 HydrophobicContact CB-CG2 4.01Å; D342-V345 PolarHBondContact O-N 3.09Å; D342-V345 PolarHBondContact OD1-N 3.45Å; D342-K346 PolarHBondContact O-N 3Å; D342-G347 PolarHBondContact N-O 3.3Å; D342-V349 HydrophobicContact CB-CB 4.49Å; D342-V349 HydrophobicContact CB-CG2 3.65Å; D342-R434 IonicContact OD2-CZ 3.65Å; D342-R434 IonicContact OD2-NH1 3.39Å; D342-R434 IonicContact OD2-NH2 3.96Å; D342-R434 PolarHBondContact OD2-NH2 3.2Å
343P96.3Very high97.8Very high100 Ų10048.5 Ų48.565%0.64926%0.262SS*.THydrogen-bonded Turntrans-58.3-32.6179.1-25.234.6000114.6V345 K346P343-V345 VanDerWaalsContact C-N 3.3Å; P343-K346 PolarHBondContact O-N 3.42Å
344A96.2Very high97.8Very high48 Ų4846 Ų4640%0.39724%0.241SC..THydrogen-bonded Turntrans-72.2-27.3178.400000111.9P294 D295 D342P294-A344 CarbonylContact C-O 3.54Å; P294-A344 VanDerWaalsContact C-O 3.31Å; P294-A344 HydrophobicContact CB-CB 4.25Å; P294-A344 HydrophobicContact CG-CB 4.1Å; D295-A344 WeakPolarHBondContact CA-O 3.32Å; D295-A344 WeakPolarHBondContact CB-O 3.32Å; D295-A344 PolarHBondContact N-O 3.17Å; D342-A344 VanDerWaalsContact C-N 3.26Å; D342-A344 PolarHBondContact O-N 3.34Å; D342-A344 WeakPolarHBondContact OD1-CA 3.38Å; D342-A344 VanDerWaalsContact OD1-CB 3.3Å; D342-A344 WeakPolarHBondContact OD1-CB 3.36Å; D342-A344 PolarHBondContact OD1-N 3.28Å
345V96.8Very high97.8Very high5 Ų545.9 Ų45.93%0.0324%0.24CC..THydrogen-bonded Turntrans-89.7-24.6175.8-175.90000112.1V289 P294 D342 P343 G347 V349 R434 T436V289-V345 HydrophobicContact CB-CG2 4.42Å; V289-V345 HydrophobicContact CG1-CG1 4.47Å; V289-V345 HydrophobicContact CG1-CG2 3.51Å; V289-V345 HydrophobicContact CG2-CG1 3.76Å; V289-V345 HydrophobicContact CG2-CG2 4.01Å; P294-V345 HydrophobicContact CB-CG2 4.13Å; P294-V345 WeakPolarHBondContact O-CA 3.41Å; D342-V345 HydrophobicContact CB-CB 4.12Å; D342-V345 HydrophobicContact CB-CG2 4.01Å; D342-V345 PolarHBondContact O-N 3.09Å; D342-V345 PolarHBondContact OD1-N 3.45Å; P343-V345 VanDerWaalsContact C-N 3.3Å; V345-G347 VanDerWaalsContact C-N 3.29Å; V345-V349 HydrophobicContact CB-CG2 3.96Å; V345-V349 HydrophobicContact CG1-CG2 4.05Å; V345-V349 HydrophobicContact CG2-CG2 3.78Å; V345-R434 VanDerWaalsContact CG2-NH2 3.29Å; V345-T436 HydrophobicContact CG1-CG2 3.81Å
346K95Very high97.7Very high124 Ų12448.9 Ų48.954%0.53926%0.256SS..THydrogen-bonded Turntrans56.145.7-167.5-54.8177.2-179174.90111W341 D342 P343W341-K346 WeakPolarHBondContact CH2-O 3.14Å; W341-K346 HydrophobicContact CZ2-CB 4.19Å; W341-K346 WeakPolarHBondContact CZ2-O 3.44Å; D342-K346 PolarHBondContact O-N 3Å; P343-K346 PolarHBondContact O-N 3.42Å
347G96.4Very high97.7Very high6 Ų649.3 Ų49.36%0.06225%0.253CS..EExtended strand (participates in β ladder)trans-168.3159.9-176.600000112.7W341 D342 V345W341-G347 VanDerWaalsContact CE3-C 3.5Å; W341-G347 VanDerWaalsContact CZ3-CA 3.42Å; D342-G347 PolarHBondContact N-O 3.3Å; V345-G347 VanDerWaalsContact C-N 3.29Å
348S98.1Very high97.6Very high13 Ų1345 Ų459%0.09122%0.222CC..EExtended strand (participates in β ladder)trans-71.1129.8167.7-63.60000110.4K340 T436 P437K340-S348 WeakPolarHBondContact O-CA 3.38Å; S348-T436 PolarHBondContact O-OG1 2.96Å; S348-P437 WeakPolarHBondContact O-CD 3.26Å
349V98.5Very high97.4Very high3 Ų339.5 Ų39.52%0.01820%0.198CC..  trans-112123.7-172.8176.80000111Q316 C339 K340 D342 V345 R434 V435Q316-V349 PolarHBondContact NE2-O 2.86Å; C339-V349 VanDerWaalsContact CB-O 3.31Å; C339-V349 WeakPolarHBondContact CB-O 3.41Å; K340-V349 PolarHBondContact O-N 3.32Å; K340-V349 VanDerWaalsContact O-N 3.07Å; D342-V349 HydrophobicContact CB-CB 4.49Å; D342-V349 HydrophobicContact CB-CG2 3.65Å; V345-V349 HydrophobicContact CB-CG2 3.96Å; V345-V349 HydrophobicContact CG1-CG2 4.05Å; V345-V349 HydrophobicContact CG2-CG2 3.78Å; V349-R434 HydrophobicContact CG1-CB 3.92Å; V349-R434 HydrophobicContact CG1-CG 4.24Å; V349-V435 CarbonylContact C-O 3.6Å; V349-V435 WeakPolarHBondContact CA-O 3.4Å
350A98.8Very high97.1Very high0 Ų042 Ų420%022%0.216CC..EExtended strand (participates in β ladder)trans-100.3164.2166.500000110.9L313 F321 I335 V435L313-A350 HydrophobicContact CD2-CB 4.47Å; F321-A350 HydrophobicContact CE1-CB 4.32Å; F321-A350 HydrophobicContact CZ-CB 4.05Å; I335-A350 HydrophobicContact CD1-CB 4.39Å; I335-A350 HydrophobicContact CG1-CB 4.14Å; I335-A350 HydrophobicContact CG2-CB 4.39Å; A350-V435 HydrophobicContact CB-CG2 4.04Å; A350-V435 PolarHBondContact N-O 3.34Å; A350-V435 PolarHBondContact O-N 3.46Å
351F98.8Very high96.8Very high23 Ų2338 Ų3810%0.10120%0.199CC..EExtended strand (participates in β ladder)trans-105.6117.5172-62-88000109.6L313 L314 Q316 M390 V432 A433 R434L313-F351 CarbonylContact C-O 3.44Å; L313-F351 WeakPolarHBondContact CA-O 3.46Å; L314-F351 HydrophobicContact CB-CB 4.34Å; L314-F351 PolarHBondContact N-O 2.98Å; L314-F351 PolarHBondContact O-N 3.21Å; Q316-F351 HydrophobicContact CG-CE2 4.23Å; F351-M390 HydrophobicContact CB-CE 4.17Å; F351-M390 HydrophobicContact CB-SD 4.45Å; F351-M390 HydrophobicContact CD1-CG 4.33Å; F351-M390 HydrophobicContact CD2-CE 3.65Å; F351-M390 HydrophobicContact CE1-CG 4.45Å; F351-M390 HydrophobicContact CE2-CE 4.18Å; F351-M390 HydrophobicContact CG-CE 3.95Å; F351-M390 HydrophobicContact CG-CG 4.43Å; F351-M390 HydrophobicContact CG-SD 4.41Å; F351-V432 HydrophobicContact CB-CG2 4Å; F351-V432 HydrophobicContact CD1-CG2 3.92Å; F351-V432 HydrophobicContact CG-CG2 4.41Å; F351-A433 CarbonylContact C-O 3.5Å; F351-A433 WeakPolarHBondContact CA-O 3.34Å; F351-R434 HydrophobicContact CD1-CG 4.03Å; F351-R434 HydrophobicContact CE1-CG 3.84Å
352L98.9Very high96.5Very high1 Ų130.6 Ų30.61%0.00517%0.171CC..EExtended strand (participates in β ladder)trans-86.3116.9171.3174.762.3000109.2A302 L306 R307 I312 L313 V354 F377 V432 A433 V435A302-L352 HydrophobicContact CB-CD2 4.24Å; L306-L352 HydrophobicContact CB-CD2 4.18Å; L306-L352 HydrophobicContact CD1-CD2 3.85Å; R307-L352 HydrophobicContact CG-CD1 4.36Å; I312-L352 WeakPolarHBondContact O-CA 3.32Å; L313-L352 HydrophobicContact CD2-CB 4.02Å; L313-L352 HydrophobicContact CD2-CD1 3.99Å; L352-V354 HydrophobicContact CD1-CG1 4.34Å; L352-V354 HydrophobicContact CG-CG1 4.33Å; L352-F377 HydrophobicContact CD2-CZ 4.13Å; L352-V432 WeakPolarHBondContact O-CA 3.21Å; L352-A433 PolarHBondContact N-O 3.45Å; L352-A433 PolarHBondContact O-N 2.88Å; L352-V435 HydrophobicContact CB-CG1 3.96Å; L352-V435 HydrophobicContact CB-CG2 4.18Å; L352-V435 HydrophobicContact CD2-CG1 4.33Å
353V98.8Very high96.1Very high0 Ų028.6 Ų28.60%016%0.16CC..EExtended strand (participates in β ladder)trans-109.7130.7179-176.70000110.1G311 I312 L314 L386 F424 L430 Y431 V432G311-V353 WeakPolarHBondContact CA-O 3.38Å; I312-V353 HydrophobicContact CG1-CB 3.93Å; I312-V353 PolarHBondContact N-O 3.32Å; I312-V353 PolarHBondContact O-N 2.82Å; L314-V353 HydrophobicContact CD1-CG2 3.72Å; L314-V353 HydrophobicContact CG-CG2 4.07Å; V353-L386 HydrophobicContact CG1-CD2 4.06Å; V353-L386 HydrophobicContact CG2-CD1 4.3Å; V353-L386 HydrophobicContact CG2-CD2 4.21Å; V353-F424 HydrophobicContact CG1-CE1 4.38Å; V353-L430 HydrophobicContact CG1-CB 4.33Å; V353-L430 HydrophobicContact CG1-CD1 4.46Å; V353-Y431 WeakPolarHBondContact CA-O 3.38Å; V353-V432 HydrophobicContact CG2-CB 4.46Å; V353-V432 HydrophobicContact CG2-CG2 4.21Å
354V98.6Very high95.8Very high0 Ų027.7 Ų27.70%015%0.147CC..EExtended strand (participates in β ladder)trans-136.5158.2176.6-56.20000110.4L306 L352 I358 F367 F377 Y431L306-V354 HydrophobicContact CD2-CG1 4.23Å; L352-V354 HydrophobicContact CD1-CG1 4.34Å; L352-V354 HydrophobicContact CG-CG1 4.33Å; V354-I358 HydrophobicContact CB-CB 4.04Å; V354-I358 HydrophobicContact CB-CD1 3.85Å; V354-I358 HydrophobicContact CB-CG2 3.9Å; V354-I358 HydrophobicContact CG1-CD1 4.15Å; V354-I358 HydrophobicContact CG1-CG2 3.91Å; V354-F367 HydrophobicContact CG2-CE2 3.64Å; V354-F367 HydrophobicContact CG2-CZ 3.79Å; V354-F377 HydrophobicContact CG2-CD1 4.36Å; V354-F377 HydrophobicContact CG2-CE1 3.79Å; V354-F377 HydrophobicContact CG2-CZ 4.2Å; V354-Y431 HydrophobicContact CG2-CD2 4.23Å; V354-Y431 HydrophobicContact CG2-CG 4.42Å; V354-Y431 PolarHBondContact N-O 2.85Å; V354-Y431 PolarHBondContact O-N 3.45Å
355N98.2Very high95.5Very high3 Ų326.7 Ų26.72%0.01614%0.137CC..EExtended strand (participates in β ladder)trans-113.5-176.417671.5-0.8000112E357 I358 A359 T423 F424 E428 L430N355-E357 VanDerWaalsContact C-N 3.29Å; N355-E357 PolarHBondContact O-N 3.12Å; N355-E357 PolarHBondContact OD1-N 3.35Å; N355-I358 PolarHBondContact O-N 3.25Å; N355-I358 WeakPolarHBondContact OD1-CG1 3.31Å; N355-I358 PolarHBondContact OD1-N 2.83Å; N355-I358 VanDerWaalsContact OD1-N 3.09Å; N355-A359 PolarHBondContact O-N 3.04Å; N355-T423 PolarHBondContact ND2-O 3.19Å; N355-F424 HydrophobicContact CB-CD1 4.14Å; N355-F424 HydrophobicContact CB-CE1 4.08Å; N355-E428 WeakPolarHBondContact CB-OE2 3.25Å; N355-E428 PolarHBondContact ND2-OE1 2.91Å; N355-E428 PolarHBondContact ND2-OE2 2.95Å; N355-L430 HydrophobicContact CB-CD2 3.99Å
356N97.1Very high95.1Very high63 Ų6327.6 Ų27.634%0.33714%0.142SC..Hα-helixtrans-61.9-33.3-179.7-77.7-37.1000113.5A359 S360 Y431N356-A359 PolarHBondContact O-N 3.26Å; N356-S360 WeakPolarHBondContact O-CB 3.4Å; N356-S360 PolarHBondContact O-N 3.38Å; N356-Y431 VanDerWaalsContact OD1-CE2 3.24Å; N356-Y431 WeakPolarHBondContact OD1-CE2 3.42Å; N356-Y431 PolarHBondContact OD1-OH 3.25Å
357E96.8Very high95.1Very high87 Ų8721.7 Ų21.741%0.40712%0.117SC..Hα-helixtrans-67.5-43178.8-168.3-178.4165.900111.3N355 S360 K361 V422N355-E357 VanDerWaalsContact C-N 3.29Å; N355-E357 PolarHBondContact O-N 3.12Å; N355-E357 PolarHBondContact OD1-N 3.35Å; E357-S360 WeakPolarHBondContact O-CB 3.4Å; E357-S360 PolarHBondContact O-N 3.46Å; E357-K361 HydrophobicContact CG-CD 4.36Å; E357-K361 WeakPolarHBondContact O-CG 3.35Å; E357-K361 PolarHBondContact O-N 2.92Å; E357-K361 WeakPolarHBondContact OE1-CE 3.07Å; E357-K361 IonicContact OE1-NZ 2.76Å; E357-K361 PolarHBondContact OE1-NZ 2.98Å; E357-V422 HydrophobicContact CB-CG1 4.07Å; E357-V422 HydrophobicContact CG-CG1 3.92Å
358I96.4Very high94.9Very high0 Ų024 Ų240%013%0.13CC..Hα-helixtrans-63.2-45.6174.4-64.4161.4000110.9L306 F309 V354 N355 S360 K361 I362 V422 F424L306-I358 HydrophobicContact CD2-CG2 4.28Å; F309-I358 HydrophobicContact CB-CG2 4.15Å; F309-I358 WeakPolarHBondContact O-CG1 3.43Å; V354-I358 HydrophobicContact CB-CB 4.04Å; V354-I358 HydrophobicContact CB-CD1 3.85Å; V354-I358 HydrophobicContact CB-CG2 3.9Å; V354-I358 HydrophobicContact CG1-CD1 4.15Å; V354-I358 HydrophobicContact CG1-CG2 3.91Å; N355-I358 PolarHBondContact O-N 3.25Å; N355-I358 WeakPolarHBondContact OD1-CG1 3.31Å; N355-I358 PolarHBondContact OD1-N 2.83Å; N355-I358 VanDerWaalsContact OD1-N 3.09Å; I358-S360 PolarHBondContact O-N 3.45Å; I358-K361 PolarHBondContact O-N 2.74Å; I358-I362 HydrophobicContact CG2-CG1 4.34Å; I358-I362 WeakPolarHBondContact O-CG1 3.49Å; I358-I362 PolarHBondContact O-N 3.28Å; I358-V422 HydrophobicContact CD1-CG2 3.78Å; I358-V422 HydrophobicContact CG1-CG1 4Å; I358-V422 HydrophobicContact CG1-CG2 3.93Å; I358-F424 HydrophobicContact CD1-CE1 4.28Å; I358-F424 HydrophobicContact CD1-CZ 3.83Å
359A94.7Very high94.6Very high0 Ų027.7 Ų27.70%014%0.142CC..Hα-helixtrans-55.5-42.3176.500000111.7N355 N356 G363 F367N355-A359 PolarHBondContact O-N 3.04Å; N356-A359 PolarHBondContact O-N 3.26Å; A359-G363 CarbonylContact O-C 3.59Å; A359-G363 PolarHBondContact O-N 3.41Å; A359-F367 HydrophobicContact CB-CB 4.17Å; A359-F367 HydrophobicContact CB-CD1 3.36Å; A359-F367 HydrophobicContact CB-CD2 4Å; A359-F367 HydrophobicContact CB-CE1 3.65Å; A359-F367 HydrophobicContact CB-CE2 4.28Å; A359-F367 HydrophobicContact CB-CG 3.53Å; A359-F367 HydrophobicContact CB-CZ 4.11Å
360S92.7Very high94.5Very high63 Ų6328.4 Ų28.444%0.44115%0.145SC..Hα-helixtrans-65.4-47.4175.1-170.70000112.5N356 E357 I358 I362 G363N356-S360 WeakPolarHBondContact O-CB 3.4Å; N356-S360 PolarHBondContact O-N 3.38Å; E357-S360 WeakPolarHBondContact O-CB 3.4Å; E357-S360 PolarHBondContact O-N 3.46Å; I358-S360 PolarHBondContact O-N 3.45Å; S360-I362 PolarHBondContact O-N 3.32Å; S360-G363 WeakPolarHBondContact O-CA 3.49Å; S360-G363 PolarHBondContact O-N 3.48Å
361K91.9Very high94.4Very high57 Ų5730.4 Ų30.425%0.24815%0.152CC..Hα-helixtrans-63-38-179.8-75174179.6167.40113.4Q135 F309 E357 I358 G363 P421Q135-K361 PolarHBondContact NE2-O 2.74Å; F309-K361 HydrophobicContact CB-CB 4.24Å; F309-K361 HydrophobicContact CB-CD 4.32Å; F309-K361 HydrophobicContact CD1-CB 3.82Å; F309-K361 HydrophobicContact CD1-CD 3.93Å; F309-K361 HydrophobicContact CD1-CG 4.36Å; F309-K361 HydrophobicContact CD2-CB 3.96Å; F309-K361 HydrophobicContact CE1-CB 4.1Å; F309-K361 HydrophobicContact CE2-CB 4.24Å; F309-K361 HydrophobicContact CG-CB 3.75Å; F309-K361 HydrophobicContact CG-CD 4.3Å; F309-K361 HydrophobicContact CZ-CB 4.3Å; E357-K361 HydrophobicContact CG-CD 4.36Å; E357-K361 WeakPolarHBondContact O-CG 3.35Å; E357-K361 PolarHBondContact O-N 2.92Å; E357-K361 WeakPolarHBondContact OE1-CE 3.07Å; E357-K361 IonicContact OE1-NZ 2.76Å; E357-K361 PolarHBondContact OE1-NZ 2.98Å; I358-K361 PolarHBondContact O-N 2.74Å; K361-G363 PolarHBondContact O-N 2.84Å; K361-P421 PolarHBondContact NZ-O 3.38Å
362I91.1Very high94.2Very high4 Ų433.9 Ų33.92%0.02117%0.168CC..Hα-helixtrans-64.2-28.8172.4-72.8-73.8000112A305 L306 F309 I358 S360 T366 F367A305-I362 HydrophobicContact CB-CD1 3.65Å; L306-I362 HydrophobicContact CD2-CD1 4.03Å; L306-I362 HydrophobicContact CD2-CG1 3.76Å; L306-I362 HydrophobicContact CG-CD1 4.07Å; L306-I362 HydrophobicContact CG-CG1 4.37Å; F309-I362 HydrophobicContact CD2-CD1 3.56Å; F309-I362 HydrophobicContact CD2-CG1 3.81Å; F309-I362 HydrophobicContact CE2-CD1 3.87Å; F309-I362 HydrophobicContact CE2-CG1 4.3Å; I358-I362 HydrophobicContact CG2-CG1 4.34Å; I358-I362 WeakPolarHBondContact O-CG1 3.49Å; I358-I362 PolarHBondContact O-N 3.28Å; S360-I362 PolarHBondContact O-N 3.32Å; I362-T366 HydrophobicContact CG2-CG2 3.81Å; I362-F367 HydrophobicContact CG2-CB 4.49Å
363G89.1Confident93.9Very high0 Ų038.1 Ų38.10%019%0.193CC..  trans104.2116.9-171.400000110.6P152 A359 S360 K361 P365 T366 F367P152-G363 VanDerWaalsContact CG-CA 3.48Å; A359-G363 CarbonylContact O-C 3.59Å; A359-G363 PolarHBondContact O-N 3.41Å; S360-G363 WeakPolarHBondContact O-CA 3.49Å; S360-G363 PolarHBondContact O-N 3.48Å; K361-G363 PolarHBondContact O-N 2.84Å; G363-P365 VanDerWaalsContact C-CD 3.42Å; G363-P365 VanDerWaalsContact C-N 3.28Å; G363-P365 VanDerWaalsContact O-N 3.16Å; G363-T366 WeakPolarHBondContact O-CA 3.46Å; G363-T366 WeakPolarHBondContact O-CB 3.49Å; G363-T366 PolarHBondContact O-N 3.29Å; G363-F367 PolarHBondContact O-N 2.79Å
364Q88.8Confident93.7Very high81 Ų8140.5 Ų40.538%0.37920%0.203SC..Hα-helixtrans-51.1-40-176.9-72.1-66.51600114.3T366 F367 T368Q364-T366 PolarHBondContact O-N 3.06Å; Q364-F367 PolarHBondContact O-N 3.04Å; Q364-T368 WeakPolarHBondContact O-CB 3.48Å; Q364-T368 PolarHBondContact O-N 3.23Å; Q364-T368 PolarHBondContact O-OG1 2.76Å
365P89.3Confident93.6Very high27 Ų2745.1 Ų45.118%0.17523%0.225CC..Hα-helixtrans-58.8-47.2173.5-32.542.3000114.2G156 A158 G363 T368 Y369G156-P365 WeakPolarHBondContact O-CB 3.23Å; G156-P365 WeakPolarHBondContact O-CG 3.31Å; A158-P365 HydrophobicContact CB-CB 4.11Å; G363-P365 VanDerWaalsContact C-CD 3.42Å; G363-P365 VanDerWaalsContact C-N 3.28Å; G363-P365 VanDerWaalsContact O-N 3.16Å; P365-T368 PolarHBondContact O-N 2.88Å; P365-Y369 WeakPolarHBondContact O-CB 3.49Å; P365-Y369 PolarHBondContact O-N 3.43Å
366T90.2Very high93.6Very high24 Ų2445.3 Ų45.315%0.14723%0.226CC..Hα-helixtrans-65.5-42.9-179.7-59.90000110.2I362 G363 Q364 Y369 Y370I362-T366 HydrophobicContact CG2-CG2 3.81Å; G363-T366 WeakPolarHBondContact O-CA 3.46Å; G363-T366 WeakPolarHBondContact O-CB 3.49Å; G363-T366 PolarHBondContact O-N 3.29Å; Q364-T366 PolarHBondContact O-N 3.06Å; T366-Y369 WeakPolarHBondContact O-CB 3.44Å; T366-Y369 PolarHBondContact O-N 3.13Å; T366-Y370 HydrophobicContact CG2-CD2 4.34Å; T366-Y370 HydrophobicContact CG2-CE2 3.59Å; T366-Y370 VanDerWaalsContact O-CD2 3.23Å; T366-Y370 WeakPolarHBondContact O-CD2 3.46Å; T366-Y370 PolarHBondContact O-N 3.5Å
367F93.6Very high93.7Very high0 Ų042.8 Ų42.80%021%0.212CC..Hα-helixtrans-66.4-45.1176.9-171.1-101.6000112.1L306 V354 A359 I362 G363 Q364 Y369 Y370 W371 F377 Y431L306-F367 HydrophobicContact CD2-CD2 4.43Å; V354-F367 HydrophobicContact CG2-CE2 3.64Å; V354-F367 HydrophobicContact CG2-CZ 3.79Å; A359-F367 HydrophobicContact CB-CB 4.17Å; A359-F367 HydrophobicContact CB-CD1 3.36Å; A359-F367 HydrophobicContact CB-CD2 4Å; A359-F367 HydrophobicContact CB-CE1 3.65Å; A359-F367 HydrophobicContact CB-CE2 4.28Å; A359-F367 HydrophobicContact CB-CG 3.53Å; A359-F367 HydrophobicContact CB-CZ 4.11Å; I362-F367 HydrophobicContact CG2-CB 4.49Å; G363-F367 PolarHBondContact O-N 2.79Å; Q364-F367 PolarHBondContact O-N 3.04Å; F367-Y369 PolarHBondContact O-N 3.31Å; F367-Y370 PolarHBondContact O-N 2.85Å; F367-W371 HydrophobicContact CD1-CB 4.48Å; F367-W371 HydrophobicContact CE1-CB 4.19Å; F367-W371 HydrophobicContact CE1-CE3 4.28Å; F367-W371 WeakPolarHBondContact O-CB 3.37Å; F367-W371 PolarHBondContact O-N 2.84Å; F367-F377 HydrophobicContact CD2-CE2 4.45Å; F367-F377 AromaticContact CE2-CD2 3.9Å; F367-F377 HydrophobicContact CE2-CD2 3.9Å; F367-F377 HydrophobicContact CE2-CE1 4.4Å; F367-F377 AromaticContact CE2-CE2 3.73Å; F367-F377 HydrophobicContact CE2-CE2 3.73Å; F367-F377 HydrophobicContact CE2-CG 4.3Å; F367-F377 HydrophobicContact CE2-CZ 4.01Å; F367-F377 HydrophobicContact CZ-CD1 4.46Å; F367-F377 HydrophobicContact CZ-CD2 4.17Å; F367-F377 HydrophobicContact CZ-CE2 4.42Å; F367-F377 HydrophobicContact CZ-CG 4.19Å; F367-Y431 AromaticContact CE1-CD1 3.76Å; F367-Y431 HydrophobicContact CE1-CD1 3.76Å; F367-Y431 AromaticContact CE1-CD2 3.94Å; F367-Y431 HydrophobicContact CE1-CD2 3.94Å; F367-Y431 AromaticContact CE1-CE1 3.86Å; F367-Y431 HydrophobicContact CE1-CE1 3.86Å; F367-Y431 HydrophobicContact CE1-CE2 4.04Å; F367-Y431 AromaticContact CE1-CG 3.8Å; F367-Y431 HydrophobicContact CE1-CG 3.8Å; F367-Y431 AromaticContact CZ-CD1 3.87Å; F367-Y431 HydrophobicContact CZ-CD1 3.87Å; F367-Y431 AromaticContact CZ-CD2 3.77Å; F367-Y431 HydrophobicContact CZ-CD2 3.77Å; F367-Y431 HydrophobicContact CZ-CE1 4.42Å; F367-Y431 HydrophobicContact CZ-CE2 4.34Å; F367-Y431 AromaticContact CZ-CG 3.52Å; F367-Y431 HydrophobicContact CZ-CG 3.52Å
368T93.2Very high93.8Very high56 Ų5643.9 Ų43.934%0.34422%0.215SC..Hα-helixtrans-59.1-36.1175.3-610000111.5Q364 P365 W371 K372 V373Q364-T368 WeakPolarHBondContact O-CB 3.48Å; Q364-T368 PolarHBondContact O-N 3.23Å; Q364-T368 PolarHBondContact O-OG1 2.76Å; P365-T368 PolarHBondContact O-N 2.88Å; T368-W371 PolarHBondContact O-N 2.67Å; T368-K372 HydrophobicContact CG2-CB 4.02Å; T368-K372 HydrophobicContact CG2-CG 4.06Å; T368-K372 WeakPolarHBondContact O-CA 3.16Å; T368-K372 WeakPolarHBondContact O-CB 3.27Å; T368-K372 PolarHBondContact O-N 2.85Å; T368-V373 PolarHBondContact O-N 3.33Å
369Y92.2Very high93.8Very high90 Ų9046.7 Ų46.735%0.35323%0.23SC..Iπ-helixtrans-60.9-47.2172.5177.4-100.2000111.8P365 T366 F367 V373 K374P365-Y369 WeakPolarHBondContact O-CB 3.49Å; P365-Y369 PolarHBondContact O-N 3.43Å; T366-Y369 WeakPolarHBondContact O-CB 3.44Å; T366-Y369 PolarHBondContact O-N 3.13Å; F367-Y369 PolarHBondContact O-N 3.31Å; Y369-V373 HydrophobicContact CD2-CB 3.83Å; Y369-V373 HydrophobicContact CD2-CG1 3.87Å; Y369-V373 HydrophobicContact CD2-CG2 4.17Å; Y369-V373 HydrophobicContact CE2-CB 4.28Å; Y369-V373 HydrophobicContact CE2-CG1 3.85Å; Y369-V373 HydrophobicContact CG-CB 4.5Å; Y369-V373 WeakPolarHBondContact O-CB 3.35Å; Y369-V373 PolarHBondContact O-N 3.36Å; Y369-K374 HydrophobicContact CD1-CG 4.11Å; Y369-K374 HydrophobicContact CE1-CD 4.25Å; Y369-K374 HydrophobicContact CE1-CG 3.63Å; Y369-K374 HydrophobicContact CE2-CD 4.44Å; Y369-K374 HydrophobicContact CE2-CG 4.25Å; Y369-K374 WeakPolarHBondContact O-CB 3.14Å; Y369-K374 PolarHBondContact O-N 2.71Å
370Y95Very high94Very high18 Ų1847.3 Ų47.37%0.07123%0.234CC..Iπ-helixtrans-66.9-38.2176.6-59.7-47.8000113F288 P303 T366 F367 H375 F376F288-Y370 AromaticContact CE2-CD1 3.9Å; F288-Y370 HydrophobicContact CE2-CD1 3.9Å; F288-Y370 HydrophobicContact CE2-CE1 4.26Å; F288-Y370 HydrophobicContact CE2-CG 4.08Å; F288-Y370 HydrophobicContact CZ-CG 4.32Å; P303-Y370 HydrophobicContact CG-CE2 3.81Å; P303-Y370 VanDerWaalsContact CG-OH 3.27Å; P303-Y370 WeakPolarHBondContact CG-OH 3.26Å; T366-Y370 HydrophobicContact CG2-CD2 4.34Å; T366-Y370 HydrophobicContact CG2-CE2 3.59Å; T366-Y370 VanDerWaalsContact O-CD2 3.23Å; T366-Y370 WeakPolarHBondContact O-CD2 3.46Å; T366-Y370 PolarHBondContact O-N 3.5Å; F367-Y370 PolarHBondContact O-N 2.85Å; Y370-H375 PolarHBondContact O-N 3.22Å; Y370-F376 HydrophobicContact CD1-CD2 4.07Å; Y370-F376 HydrophobicContact CD1-CE2 4.31Å; Y370-F376 PolarHBondContact O-N 2.94Å
371W96.3Very high94.3Very high42 Ų4247.2 Ų47.216%0.15924%0.237CC..Iπ-helixtrans-81-57.5-176.1174.632.7000113.5F367 T368 H375 F377 D379 Y431F367-W371 HydrophobicContact CD1-CB 4.48Å; F367-W371 HydrophobicContact CE1-CB 4.19Å; F367-W371 HydrophobicContact CE1-CE3 4.28Å; F367-W371 WeakPolarHBondContact O-CB 3.37Å; F367-W371 PolarHBondContact O-N 2.84Å; T368-W371 PolarHBondContact O-N 2.67Å; W371-H375 VanDerWaalsContact O-CA 3.23Å; W371-H375 WeakPolarHBondContact O-CA 3.37Å; W371-H375 PolarHBondContact O-N 2.96Å; W371-F377 HydrophobicContact CB-CB 4.12Å; W371-F377 VanDerWaalsContact CD1-O 3.31Å; W371-F377 HydrophobicContact CG-CB 4.28Å; W371-D379 HydrophobicContact CZ2-CB 3.63Å; W371-D379 VanDerWaalsContact CZ2-CG 3.44Å; W371-D379 PolarHBondContact NE1-OD1 2.81Å; W371-Y431 HydrophobicContact CD2-CD1 4.09Å; W371-Y431 AromaticContact CD2-CE1 3.81Å; W371-Y431 HydrophobicContact CD2-CE1 3.81Å; W371-Y431 AromaticContact CE2-CD1 3.98Å; W371-Y431 AromaticContact CE2-CE1 3.68Å; W371-Y431 AromaticContact CE3-CE1 3.87Å; W371-Y431 HydrophobicContact CE3-CE1 3.87Å; W371-Y431 HydrophobicContact CG-CD1 4.39Å; W371-Y431 AromaticContact CH2-CE1 3.69Å; W371-Y431 HydrophobicContact CH2-CE1 3.69Å; W371-Y431 HydrophobicContact CZ2-CD1 4.31Å; W371-Y431 AromaticContact CZ2-CE1 3.63Å; W371-Y431 HydrophobicContact CZ2-CE1 3.63Å; W371-Y431 AromaticContact CZ3-CE1 3.82Å; W371-Y431 HydrophobicContact CZ3-CE1 3.82Å
372K94.7Very high94.6Very high96 Ų9646.5 Ų46.542%0.41724%0.236SC..Iπ-helixtrans-94.6-28.7-170.7-63.3-59.6-164.3-170.60113.9T368 H375T368-K372 HydrophobicContact CG2-CB 4.02Å; T368-K372 HydrophobicContact CG2-CG 4.06Å; T368-K372 WeakPolarHBondContact O-CA 3.16Å; T368-K372 WeakPolarHBondContact O-CB 3.27Å; T368-K372 PolarHBondContact O-N 2.85Å; K372-H375 PolarHBondContact O-CE1 2.82Å; K372-H375 PolarHBondContact O-ND1 3.03Å; K372-H375 PolarHBondContact O-NE2 2.7Å
373V93.8Very high94.9Very high89 Ų8946.3 Ų46.354%0.53924%0.235SC..Iπ-helixtrans-92.4-47.1-179.6-178.30000111.1T368 Y369T368-V373 PolarHBondContact O-N 3.33Å; Y369-V373 HydrophobicContact CD2-CB 3.83Å; Y369-V373 HydrophobicContact CD2-CG1 3.87Å; Y369-V373 HydrophobicContact CD2-CG2 4.17Å; Y369-V373 HydrophobicContact CE2-CB 4.28Å; Y369-V373 HydrophobicContact CE2-CG1 3.85Å; Y369-V373 HydrophobicContact CG-CB 4.5Å; Y369-V373 WeakPolarHBondContact O-CB 3.35Å; Y369-V373 PolarHBondContact O-N 3.36Å
374K94.6Very high95.3Very high50 Ų5047.8 Ų47.822%0.21725%0.245CC..SBendtrans-91.6-14.1-179.8-65.7-58.4-59.9170.20114F300 Y369 F376F300-K374 HydrophobicContact CZ-CD 4.46Å; Y369-K374 HydrophobicContact CD1-CG 4.11Å; Y369-K374 HydrophobicContact CE1-CD 4.25Å; Y369-K374 HydrophobicContact CE1-CG 3.63Å; Y369-K374 HydrophobicContact CE2-CD 4.44Å; Y369-K374 HydrophobicContact CE2-CG 4.25Å; Y369-K374 WeakPolarHBondContact O-CB 3.14Å; Y369-K374 PolarHBondContact O-N 2.71Å; K374-F376 HydrophobicContact CB-CD1 4.12Å; K374-F376 HydrophobicContact CB-CD2 3.61Å; K374-F376 HydrophobicContact CB-CE1 3.98Å; K374-F376 HydrophobicContact CB-CE2 3.47Å; K374-F376 VanDerWaalsContact CB-CE2 3.47Å; K374-F376 HydrophobicContact CB-CG 3.94Å; K374-F376 HydrophobicContact CB-CZ 3.68Å; K374-F376 HydrophobicContact CD-CZ 4.34Å; K374-F376 HydrophobicContact CG-CD2 4.36Å; K374-F376 HydrophobicContact CG-CE2 3.82Å; K374-F376 HydrophobicContact CG-CZ 4.07Å; K374-F376 WeakPolarHBondContact O-CD1 3.21Å; K374-F376 PolarHBondContact O-N 2.91Å
375H96.7Very high95.8Very high98 Ų9848.2 Ų48.245%0.45425%0.248SC..  trans55.629.6179.7-53-69.3000114.3Y370 W371 K372Y370-H375 PolarHBondContact O-N 3.22Å; W371-H375 VanDerWaalsContact O-CA 3.23Å; W371-H375 WeakPolarHBondContact O-CA 3.37Å; W371-H375 PolarHBondContact O-N 2.96Å; K372-H375 PolarHBondContact O-CE1 2.82Å; K372-H375 PolarHBondContact O-ND1 3.03Å; K372-H375 PolarHBondContact O-NE2 2.7Å
376F98.1Very high96.2Very high7 Ų746.9 Ų46.93%0.03124%0.24CC..  trans-75.2-30.5176.7-61.8-31.3000112.4F288 D290 F300 Y370 K374 A433F288-F376 HydrophobicContact CB-CB 4.26Å; F288-F376 HydrophobicContact CB-CD1 4.01Å; F288-F376 HydrophobicContact CB-CD2 3.86Å; F288-F376 HydrophobicContact CB-CE1 4.28Å; F288-F376 HydrophobicContact CB-CE2 4.13Å; F288-F376 HydrophobicContact CB-CG 3.79Å; F288-F376 HydrophobicContact CB-CZ 4.32Å; F288-F376 HydrophobicContact CD1-CB 3.66Å; F288-F376 HydrophobicContact CD1-CD2 4.17Å; F288-F376 HydrophobicContact CD1-CG 4.06Å; F288-F376 HydrophobicContact CD2-CB 4.34Å; F288-F376 AromaticContact CD2-CD2 3.28Å; F288-F376 HydrophobicContact CD2-CD2 3.28Å; F288-F376 AromaticContact CD2-CE2 3.67Å; F288-F376 HydrophobicContact CD2-CE2 3.67Å; F288-F376 AromaticContact CD2-CG 3.97Å; F288-F376 HydrophobicContact CD2-CG 3.97Å; F288-F376 HydrophobicContact CE1-CB 3.99Å; F288-F376 AromaticContact CE2-CD2 3.71Å; F288-F376 HydrophobicContact CE2-CD2 3.71Å; F288-F376 HydrophobicContact CE2-CE2 4.33Å; F288-F376 HydrophobicContact CG-CB 3.86Å; F288-F376 HydrophobicContact CG-CD1 4.42Å; F288-F376 AromaticContact CG-CD2 3.52Å; F288-F376 HydrophobicContact CG-CD2 3.52Å; F288-F376 HydrophobicContact CG-CE2 4.11Å; F288-F376 AromaticContact CG-CG 3.7Å; F288-F376 HydrophobicContact CG-CG 3.7Å; F288-F376 HydrophobicContact CZ-CB 4.44Å; F288-F376 HydrophobicContact CZ-CD2 4.34Å; D290-F376 HydrophobicContact CB-CD1 4.46Å; D290-F376 HydrophobicContact CB-CE1 3.93Å; F300-F376 HydrophobicContact CB-CE2 3.46Å; F300-F376 VanDerWaalsContact CB-CE2 3.46Å; F300-F376 HydrophobicContact CB-CZ 3.57Å; F300-F376 HydrophobicContact CD1-CE2 4.22Å; F300-F376 HydrophobicContact CD1-CZ 4.44Å; F300-F376 HydrophobicContact CD2-CE2 4.15Å; F300-F376 AromaticContact CD2-CZ 3.57Å; F300-F376 HydrophobicContact CD2-CZ 3.57Å; F300-F376 HydrophobicContact CE2-CZ 4.39Å; F300-F376 AromaticContact CG-CE2 3.68Å; F300-F376 HydrophobicContact CG-CE2 3.68Å; F300-F376 AromaticContact CG-CZ 3.6Å; F300-F376 HydrophobicContact CG-CZ 3.6Å; Y370-F376 HydrophobicContact CD1-CD2 4.07Å; Y370-F376 HydrophobicContact CD1-CE2 4.31Å; Y370-F376 PolarHBondContact O-N 2.94Å; K374-F376 HydrophobicContact CB-CD1 4.12Å; K374-F376 HydrophobicContact CB-CD2 3.61Å; K374-F376 HydrophobicContact CB-CE1 3.98Å; K374-F376 HydrophobicContact CB-CE2 3.47Å; K374-F376 VanDerWaalsContact CB-CE2 3.47Å; K374-F376 HydrophobicContact CB-CG 3.94Å; K374-F376 HydrophobicContact CB-CZ 3.68Å; K374-F376 HydrophobicContact CD-CZ 4.34Å; K374-F376 HydrophobicContact CG-CD2 4.36Å; K374-F376 HydrophobicContact CG-CE2 3.82Å; K374-F376 HydrophobicContact CG-CZ 4.07Å; K374-F376 WeakPolarHBondContact O-CD1 3.21Å; K374-F376 PolarHBondContact O-N 2.91Å; F376-A433 WeakPolarHBondContact O-CA 3.37Å; F376-A433 WeakPolarHBondContact O-CB 3.31Å
377F98.5Very high96.6Very high10 Ų1045.8 Ų45.84%0.04423%0.233CC..EExtended strand (participates in β ladder)trans-99.3144.3174.7-74.4-82.5000111.3F288 L306 L352 V354 F367 W371 V432 A433F288-F377 HydrophobicContact CE1-CD2 4.36Å; F288-F377 AromaticContact CE1-CE2 3.66Å; F288-F377 HydrophobicContact CE1-CE2 3.66Å; F288-F377 AromaticContact CE1-CZ 3.86Å; F288-F377 HydrophobicContact CE1-CZ 3.86Å; F288-F377 HydrophobicContact CZ-CD2 4.47Å; F288-F377 AromaticContact CZ-CE2 3.61Å; F288-F377 HydrophobicContact CZ-CE2 3.61Å; F288-F377 HydrophobicContact CZ-CZ 4.07Å; L306-F377 HydrophobicContact CD1-CE2 4.43Å; L306-F377 HydrophobicContact CD1-CZ 4.13Å; L306-F377 HydrophobicContact CD2-CZ 4.43Å; L352-F377 HydrophobicContact CD2-CZ 4.13Å; V354-F377 HydrophobicContact CG2-CD1 4.36Å; V354-F377 HydrophobicContact CG2-CE1 3.79Å; V354-F377 HydrophobicContact CG2-CZ 4.2Å; F367-F377 HydrophobicContact CD2-CE2 4.45Å; F367-F377 AromaticContact CE2-CD2 3.9Å; F367-F377 HydrophobicContact CE2-CD2 3.9Å; F367-F377 HydrophobicContact CE2-CE1 4.4Å; F367-F377 AromaticContact CE2-CE2 3.73Å; F367-F377 HydrophobicContact CE2-CE2 3.73Å; F367-F377 HydrophobicContact CE2-CG 4.3Å; F367-F377 HydrophobicContact CE2-CZ 4.01Å; F367-F377 HydrophobicContact CZ-CD1 4.46Å; F367-F377 HydrophobicContact CZ-CD2 4.17Å; F367-F377 HydrophobicContact CZ-CE2 4.42Å; F367-F377 HydrophobicContact CZ-CG 4.19Å; W371-F377 HydrophobicContact CB-CB 4.12Å; W371-F377 VanDerWaalsContact CD1-O 3.31Å; W371-F377 HydrophobicContact CG-CB 4.28Å; F377-V432 CarbonylContact C-O 3.55Å; F377-V432 WeakPolarHBondContact CA-O 3.42Å; F377-A433 HydrophobicContact CD1-CB 3.55Å; F377-A433 HydrophobicContact CD2-CB 4.41Å; F377-A433 HydrophobicContact CE1-CB 3.51Å; F377-A433 HydrophobicContact CE2-CB 4.38Å; F377-A433 HydrophobicContact CG-CB 4.01Å; F377-A433 HydrophobicContact CZ-CB 3.95Å
378K98Very high96.8Very high109 Ų10949 Ų4947%0.47426%0.259SS..EExtended strand (participates in β ladder)trans-107.7129.2161177.862.7179.8177.50108.4V380 Y431 V432K378-V380 HydrophobicContact CG-CG1 4.48Å; K378-Y431 CarbonylContact O-C 3.52Å; K378-Y431 WeakPolarHBondContact O-CA 3.49Å; K378-V432 HydrophobicContact CB-CG1 4.19Å; K378-V432 PolarHBondContact N-O 2.08Å; K378-V432 PolarHBondContact O-N 2.93Å
379D98Very high97Very high60 Ų6050.7 Ų50.732%0.32126%0.263SS..EExtended strand (participates in β ladder)trans-80.2139.5168.953.4-58000111W371 L430 Y431W371-D379 HydrophobicContact CZ2-CB 3.63Å; W371-D379 VanDerWaalsContact CZ2-CG 3.44Å; W371-D379 PolarHBondContact NE1-OD1 2.81Å; D379-L430 WeakPolarHBondContact CA-O 3.4Å; D379-Y431 HydrophobicContact CB-CD1 3.83Å; D379-Y431 HydrophobicContact CB-CE1 3.88Å
380V98.4Very high97.3Very high12 Ų1247.3 Ų47.37%0.07325%0.251CS..EExtended strand (participates in β ladder)trans-132.9139.7174.9-63.90000109K378 N382 M385 L386 H389 T429 L430 V432K378-V380 HydrophobicContact CG-CG1 4.48Å; V380-N382 VanDerWaalsContact C-N 3.32Å; V380-N382 PolarHBondContact O-N 3.11Å; V380-M385 HydrophobicContact CB-CB 3.85Å; V380-M385 HydrophobicContact CG1-CB 4.46Å; V380-L386 HydrophobicContact CG2-CB 3.87Å; V380-L386 HydrophobicContact CG2-CD1 4.29Å; V380-H389 HydrophobicContact CG1-CB 4.1Å; V380-T429 WeakPolarHBondContact O-CA 3.35Å; V380-L430 HydrophobicContact CG2-CB 3.82Å; V380-L430 PolarHBondContact N-O 2.91Å; V380-L430 PolarHBondContact O-N 3.03Å; V380-V432 HydrophobicContact CG1-CG1 4.48Å
381A97.9Very high97.4Very high61 Ų6149.8 Ų49.850%0.50428%0.281SS..SBendtrans-71.7-23.1-167.100000114.7M385 E428A381-M385 HydrophobicContact CB-CG 4.31Å; A381-E428 CarbonylContact C-O 3.45Å; A381-E428 CarbonylContact O-C 3.55Å
382N98.4Very high97.4Very high42 Ų4249 Ų4923%0.22528%0.281CS..SBendtrans-167.8178-175.954.652.1000110.6V380 S384 M385 L386 W426 E428V380-N382 VanDerWaalsContact C-N 3.32Å; V380-N382 PolarHBondContact O-N 3.11Å; N382-S384 VanDerWaalsContact C-N 3.3Å; N382-S384 PolarHBondContact O-N 2.97Å; N382-S384 VanDerWaalsContact OD1-CB 3.3Å; N382-S384 WeakPolarHBondContact OD1-CB 3.5Å; N382-S384 PolarHBondContact OD1-N 2.95Å; N382-S384 VanDerWaalsContact OD1-N 3.11Å; N382-M385 PolarHBondContact O-N 2.87Å; N382-M385 VanDerWaalsContact O-N 3.17Å; N382-M385 PolarHBondContact OD1-N 2.86Å; N382-L386 PolarHBondContact O-N 2.92Å; N382-W426 WeakPolarHBondContact CA-O 3.31Å; N382-W426 VanDerWaalsContact CB-O 3.26Å; N382-W426 WeakPolarHBondContact CB-O 3.34Å; N382-E428 WeakPolarHBondContact CA-O 3.46Å
383G98.2Very high97.4Very high0 Ų050.6 Ų50.60%030%0.295CS..Hα-helixtrans-60.3-32178.700000114.6L386 A387 W426G383-L386 WeakPolarHBondContact O-CB 3.39Å; G383-L386 PolarHBondContact O-N 2.94Å; G383-A387 WeakPolarHBondContact O-CB 3.46Å; G383-A387 PolarHBondContact O-N 3.39Å; G383-W426 VanDerWaalsContact C-CH2 3.49Å; G383-W426 PolarHBondContact N-O 2.99Å
384S98.3Very high97.6Very high31 Ų3150 Ų5022%0.21729%0.288CS..Hα-helixtrans-66-42.9174.6-177.10000111.3N382 L386 A387 A388 N394N382-S384 VanDerWaalsContact C-N 3.3Å; N382-S384 PolarHBondContact O-N 2.97Å; N382-S384 VanDerWaalsContact OD1-CB 3.3Å; N382-S384 WeakPolarHBondContact OD1-CB 3.5Å; N382-S384 PolarHBondContact OD1-N 2.95Å; N382-S384 VanDerWaalsContact OD1-N 3.11Å; S384-L386 VanDerWaalsContact C-N 3.32Å; S384-L386 PolarHBondContact O-N 3.33Å; S384-A387 PolarHBondContact O-N 3.32Å; S384-A388 WeakPolarHBondContact O-CB 3.41Å; S384-A388 PolarHBondContact O-N 2.88Å; S384-N394 PolarHBondContact OG-ND2 3.5Å
385M98.5Very high97.7Very high90 Ų9052.3 Ų52.344%0.44330%0.3SS..Hα-helixtrans-69.3-29.8175.3-64.5-60.3101.300112.4V380 A381 N382 H389V380-M385 HydrophobicContact CB-CB 3.85Å; V380-M385 HydrophobicContact CG1-CB 4.46Å; A381-M385 HydrophobicContact CB-CG 4.31Å; N382-M385 PolarHBondContact O-N 2.87Å; N382-M385 VanDerWaalsContact O-N 3.17Å; N382-M385 PolarHBondContact OD1-N 2.86Å; M385-H389 VanDerWaalsContact O-CB 3.29Å; M385-H389 WeakPolarHBondContact O-CB 3.45Å; M385-H389 PolarHBondContact O-N 3.17Å
386L98.5Very high97.7Very high0 Ų048.9 Ų48.90%029%0.289CS..Hα-helixtrans-64.5-48.5170.3179.159.8000111.3L314 V353 V380 N382 G383 S384 A388 H389 M390 I397 L430 V432L314-L386 HydrophobicContact CD1-CD2 4.49Å; V353-L386 HydrophobicContact CG1-CD2 4.06Å; V353-L386 HydrophobicContact CG2-CD1 4.3Å; V353-L386 HydrophobicContact CG2-CD2 4.21Å; V380-L386 HydrophobicContact CG2-CB 3.87Å; V380-L386 HydrophobicContact CG2-CD1 4.29Å; N382-L386 PolarHBondContact O-N 2.92Å; G383-L386 WeakPolarHBondContact O-CB 3.39Å; G383-L386 PolarHBondContact O-N 2.94Å; S384-L386 VanDerWaalsContact C-N 3.32Å; S384-L386 PolarHBondContact O-N 3.33Å; L386-A388 PolarHBondContact O-N 2.81Å; L386-H389 PolarHBondContact O-N 3.03Å; L386-M390 HydrophobicContact CD1-CG 4.14Å; L386-M390 HydrophobicContact CD1-SD 3.71Å; L386-M390 HydrophobicContact CG-SD 3.97Å; L386-M390 WeakPolarHBondContact O-CG 3.44Å; L386-M390 PolarHBondContact O-N 3.14Å; L386-I397 HydrophobicContact CD2-CD1 4.43Å; L386-I397 HydrophobicContact CD2-CG2 3.94Å; L386-I397 HydrophobicContact CG-CD1 4.43Å; L386-I397 HydrophobicContact CG-CG2 4.4Å; L386-L430 HydrophobicContact CB-CD1 4.39Å; L386-L430 HydrophobicContact CD2-CD1 3.73Å; L386-V432 HydrophobicContact CD1-CB 3.89Å; L386-V432 HydrophobicContact CD1-CG1 4.09Å; L386-V432 HydrophobicContact CD1-CG2 4.13Å
387A98.4Very high97.7Very high0 Ų048.6 Ų48.60%029%0.287CS..Hα-helixtrans-58.5-47.5177.700000111.4G383 S384 H389 M390 G391 V392 N394 I397G383-A387 WeakPolarHBondContact O-CB 3.46Å; G383-A387 PolarHBondContact O-N 3.39Å; S384-A387 PolarHBondContact O-N 3.32Å; A387-H389 PolarHBondContact O-N 3.23Å; A387-M390 PolarHBondContact O-N 2.76Å; A387-G391 PolarHBondContact O-N 3.04Å; A387-V392 CarbonylContact C-O 3.56Å; A387-V392 HydrophobicContact CB-CG2 4.23Å; A387-V392 WeakPolarHBondContact CB-O 3.03Å; A387-V392 PolarHBondContact O-N 2.83Å; A387-N394 VanDerWaalsContact CB-OD1 3.25Å; A387-N394 WeakPolarHBondContact CB-OD1 3.38Å; A387-I397 HydrophobicContact CB-CB 4.25Å; A387-I397 HydrophobicContact CB-CG1 3.68Å
388A98.1Very high97.7Very high68 Ų6853.3 Ų53.356%0.56231%0.306SS*.Hα-helixtrans-59.7-42.917500000112.5S384 L386 M390 G391S384-A388 WeakPolarHBondContact O-CB 3.41Å; S384-A388 PolarHBondContact O-N 2.88Å; L386-A388 PolarHBondContact O-N 2.81Å; A388-M390 VanDerWaalsContact C-N 3.33Å; A388-M390 PolarHBondContact O-N 2.98Å; A388-G391 PolarHBondContact O-N 2.69Å
389H97.4Very high97.7Very high91 Ų9155 Ų5542%0.42131%0.309SS..Hα-helixtrans-64.9-36.3177.7-17770.3000112.9V380 M385 L386 A387 V432V380-H389 HydrophobicContact CG1-CB 4.1Å; M385-H389 VanDerWaalsContact O-CB 3.29Å; M385-H389 WeakPolarHBondContact O-CB 3.45Å; M385-H389 PolarHBondContact O-N 3.17Å; L386-H389 PolarHBondContact O-N 3.03Å; A387-H389 PolarHBondContact O-N 3.23Å; H389-V432 VanDerWaalsContact CD2-CG1 3.4Å; H389-V432 WeakPolarHBondContact CD2-CG1 3.48Å
390M97.2Very high97.8Very high20 Ų2052.7 Ų52.710%0.09930%0.297CS..Hα-helixtrans-83.4-11.8178.9-69.8178.460.400113.4L314 N315 F351 L386 A387 A388 V392 I397L314-M390 HydrophobicContact CB-CE 3.85Å; L314-M390 HydrophobicContact CD1-CE 4.1Å; L314-M390 HydrophobicContact CD1-SD 4.01Å; N315-M390 WeakPolarHBondContact O-CE 3.45Å; F351-M390 HydrophobicContact CB-CE 4.17Å; F351-M390 HydrophobicContact CB-SD 4.45Å; F351-M390 HydrophobicContact CD1-CG 4.33Å; F351-M390 HydrophobicContact CD2-CE 3.65Å; F351-M390 HydrophobicContact CE1-CG 4.45Å; F351-M390 HydrophobicContact CE2-CE 4.18Å; F351-M390 HydrophobicContact CG-CE 3.95Å; F351-M390 HydrophobicContact CG-CG 4.43Å; F351-M390 HydrophobicContact CG-SD 4.41Å; L386-M390 HydrophobicContact CD1-CG 4.14Å; L386-M390 HydrophobicContact CD1-SD 3.71Å; L386-M390 HydrophobicContact CG-SD 3.97Å; L386-M390 WeakPolarHBondContact O-CG 3.44Å; L386-M390 PolarHBondContact O-N 3.14Å; A387-M390 PolarHBondContact O-N 2.76Å; A388-M390 VanDerWaalsContact C-N 3.33Å; A388-M390 PolarHBondContact O-N 2.98Å; M390-V392 HydrophobicContact CB-CG1 4.37Å; M390-V392 HydrophobicContact CB-CG2 4.02Å; M390-I397 HydrophobicContact CE-CD1 4.37Å; M390-I397 HydrophobicContact SD-CD1 3.98Å
391G96.4Very high97.8Very high69 Ų6952.3 Ų52.371%0.71130%0.295SS*.THydrogen-bonded Turntrans6938.2-175.600000113.1A387 A388A387-G391 PolarHBondContact O-N 3.04Å; A388-G391 PolarHBondContact O-N 2.69Å
392V97Very high97.8Very high25 Ų2556 Ų5615%0.15230%0.297CS..  trans-126162.6-179.8-58.50000111.4Q316 A387 M390 I397Q316-V392 WeakPolarHBondContact O-CG1 3.22Å; A387-V392 CarbonylContact C-O 3.56Å; A387-V392 HydrophobicContact CB-CG2 4.23Å; A387-V392 WeakPolarHBondContact CB-O 3.03Å; A387-V392 PolarHBondContact O-N 2.83Å; M390-V392 HydrophobicContact CB-CG1 4.37Å; M390-V392 HydrophobicContact CB-CG2 4.02Å; V392-I397 HydrophobicContact CG2-CD1 3.86Å; V392-I397 HydrophobicContact CG2-CG1 3.7Å
393D94.6Very high97.8Very high131 Ų13158.4 Ų58.470%0.70131%0.309SS*.  trans-65.4141.9177.7-66.3-50.1000112.4E395 A396D393-E395 PolarHBondContact O-N 3.21Å; D393-A396 WeakPolarHBondContact O-CB 3.26Å; D393-A396 PolarHBondContact O-N 3.48Å
394N97.5Very high97.8Very high76 Ų7658.4 Ų58.441%0.40631%0.309SS..Hα-helixtrans-53.4-39.5175.7-79.3-2.7000112.3S384 A387 A396 I397 Y398 W426S384-N394 PolarHBondContact OG-ND2 3.5Å; A387-N394 VanDerWaalsContact CB-OD1 3.25Å; A387-N394 WeakPolarHBondContact CB-OD1 3.38Å; N394-A396 VanDerWaalsContact C-N 3.29Å; N394-A396 PolarHBondContact O-N 2.93Å; N394-I397 PolarHBondContact O-N 3.35Å; N394-Y398 VanDerWaalsContact O-CB 3.31Å; N394-Y398 WeakPolarHBondContact O-CB 3.41Å; N394-Y398 PolarHBondContact O-N 3.05Å; N394-W426 HydrophobicContact CB-CH2 4.19Å
395E97.7Very high97.8Very high98 Ų9858.9 Ų58.946%0.45831%0.309SS..Hα-helixtrans-61.5-36.6-179.9-17864.4-178.300112.3D393 Y398 R399D393-E395 PolarHBondContact O-N 3.21Å; E395-Y398 PolarHBondContact O-N 2.93Å; E395-R399 WeakPolarHBondContact O-CB 3.29Å; E395-R399 WeakPolarHBondContact O-CG 3.25Å; E395-R399 PolarHBondContact O-N 2.97Å; E395-R399 IonicContact OE1-CZ 3.24Å; E395-R399 VanDerWaalsContact OE1-CZ 3.24Å; E395-R399 IonicContact OE1-NE 2.7Å; E395-R399 PolarHBondContact OE1-NE 2.7Å; E395-R399 IonicContact OE1-NH2 2.88Å; E395-R399 PolarHBondContact OE1-NH2 2.72Å
396A97.5Very high97.8Very high27 Ų2756.8 Ų56.822%0.22331%0.307CS..Hα-helixtrans-66.9-43.6-18000000111.8D393 N394 T400D393-A396 WeakPolarHBondContact O-CB 3.26Å; D393-A396 PolarHBondContact O-N 3.48Å; N394-A396 VanDerWaalsContact C-N 3.29Å; N394-A396 PolarHBondContact O-N 2.93Å; A396-T400 WeakPolarHBondContact O-CB 3.13Å; A396-T400 PolarHBondContact O-N 3.08Å; A396-T400 VanDerWaalsContact O-N 3.13Å; A396-T400 PolarHBondContact O-OG1 3.49Å
397I98.2Very high97.8Very high0 Ų057.9 Ų57.90%031%0.314CS..Hα-helixtrans-68.7-43.9174.8-62.3-60.7000110.4L314 L386 A387 M390 V392 N394 R399 T400 L401 W426L314-I397 HydrophobicContact CD1-CD1 4Å; L386-I397 HydrophobicContact CD2-CD1 4.43Å; L386-I397 HydrophobicContact CD2-CG2 3.94Å; L386-I397 HydrophobicContact CG-CD1 4.43Å; L386-I397 HydrophobicContact CG-CG2 4.4Å; A387-I397 HydrophobicContact CB-CB 4.25Å; A387-I397 HydrophobicContact CB-CG1 3.68Å; M390-I397 HydrophobicContact CE-CD1 4.37Å; M390-I397 HydrophobicContact SD-CD1 3.98Å; V392-I397 HydrophobicContact CG2-CD1 3.86Å; V392-I397 HydrophobicContact CG2-CG1 3.7Å; N394-I397 PolarHBondContact O-N 3.35Å; I397-R399 PolarHBondContact O-N 3.3Å; I397-T400 PolarHBondContact O-N 3.1Å; I397-T400 VanDerWaalsContact O-N 3.16Å; I397-L401 HydrophobicContact CG2-CD1 4.08Å; I397-L401 HydrophobicContact CG2-CG 4.19Å; I397-L401 WeakPolarHBondContact O-CG 3.22Å; I397-L401 PolarHBondContact O-N 3.3Å; I397-W426 HydrophobicContact CB-CZ3 4.27Å; I397-W426 HydrophobicContact CG2-CZ3 3.96Å
398Y98.4Very high97.7Very high109 Ų10958.6 Ų58.643%0.42732%0.32SS..Hα-helixtrans-56.9-51.2-179.4-178.9-92.5000111.1N394 E395 T400 L401 Y402 W426N394-Y398 VanDerWaalsContact O-CB 3.31Å; N394-Y398 WeakPolarHBondContact O-CB 3.41Å; N394-Y398 PolarHBondContact O-N 3.05Å; E395-Y398 PolarHBondContact O-N 2.93Å; Y398-T400 VanDerWaalsContact C-N 3.34Å; Y398-T400 PolarHBondContact O-N 3.01Å; Y398-L401 PolarHBondContact O-N 3.06Å; Y398-Y402 VanDerWaalsContact O-CB 3.25Å; Y398-Y402 WeakPolarHBondContact O-CB 3.16Å; Y398-Y402 PolarHBondContact O-N 2.86Å; Y398-W426 VanDerWaalsContact CA-CZ3 3.46Å; Y398-W426 AromaticContact CD2-CD2 3.82Å; Y398-W426 HydrophobicContact CD2-CD2 3.82Å; Y398-W426 AromaticContact CD2-CE3 3.64Å; Y398-W426 HydrophobicContact CD2-CE3 3.64Å; Y398-W426 HydrophobicContact CD2-CG 4.28Å; Y398-W426 HydrophobicContact CD2-CZ3 4.04Å; Y398-W426 HydrophobicContact CG-CE3 4.32Å; Y398-W426 HydrophobicContact CG-CZ3 4.33Å
399R98.1Very high97.7Very high144 Ų14459.4 Ų59.454%0.54333%0.327SS..Hα-helixtrans-58.9-44.6175.6-72.9-175.2-174.5-143.6-1.7112.1E395 I397 L401 Y402 D403E395-R399 WeakPolarHBondContact O-CB 3.29Å; E395-R399 WeakPolarHBondContact O-CG 3.25Å; E395-R399 PolarHBondContact O-N 2.97Å; E395-R399 IonicContact OE1-CZ 3.24Å; E395-R399 VanDerWaalsContact OE1-CZ 3.24Å; E395-R399 IonicContact OE1-NE 2.7Å; E395-R399 PolarHBondContact OE1-NE 2.7Å; E395-R399 IonicContact OE1-NH2 2.88Å; E395-R399 PolarHBondContact OE1-NH2 2.72Å; I397-R399 PolarHBondContact O-N 3.3Å; R399-L401 PolarHBondContact O-N 2.74Å; R399-Y402 PolarHBondContact O-N 3.3Å; R399-D403 VanDerWaalsContact O-CB 3.29Å; R399-D403 WeakPolarHBondContact O-CB 3.25Å; R399-D403 PolarHBondContact O-N 2.88Å
400T98.3Very high97.7Very high12 Ų1260.1 Ų60.17%0.07434%0.337CS..Hα-helixtrans-61-43.4-179.1-630000112.6L314 G318 R320 A396 I397 Y398 Y404L314-T400 HydrophobicContact CD2-CG2 3.64Å; G318-T400 PolarHBondContact O-OG1 3.09Å; R320-T400 HydrophobicContact CG-CG2 3.85Å; A396-T400 WeakPolarHBondContact O-CB 3.13Å; A396-T400 PolarHBondContact O-N 3.08Å; A396-T400 VanDerWaalsContact O-N 3.13Å; A396-T400 PolarHBondContact O-OG1 3.49Å; I397-T400 PolarHBondContact O-N 3.1Å; I397-T400 VanDerWaalsContact O-N 3.16Å; Y398-T400 VanDerWaalsContact C-N 3.34Å; Y398-T400 PolarHBondContact O-N 3.01Å; T400-Y404 WeakPolarHBondContact O-CB 3.31Å; T400-Y404 PolarHBondContact O-N 3.45Å; T400-Y404 VanDerWaalsContact O-N 3.14Å
401L98.4Very high97.7Very high4 Ų463.7 Ų63.72%0.02136%0.357CS..Hα-helixtrans-71.5-38.6177.1-59.1-173.7000111.6I312 I397 Y398 R399 N405 F424 W426 L430I312-L401 HydrophobicContact CD1-CD2 3.9Å; I397-L401 HydrophobicContact CG2-CD1 4.08Å; I397-L401 HydrophobicContact CG2-CG 4.19Å; I397-L401 WeakPolarHBondContact O-CG 3.22Å; I397-L401 PolarHBondContact O-N 3.3Å; Y398-L401 PolarHBondContact O-N 3.06Å; R399-L401 PolarHBondContact O-N 2.74Å; L401-N405 VanDerWaalsContact O-CG 3.25Å; L401-N405 PolarHBondContact O-N 3.41Å; L401-N405 VanDerWaalsContact O-N 3.09Å; L401-N405 PolarHBondContact O-ND2 3.49Å; L401-F424 HydrophobicContact CB-CB 4.39Å; L401-F424 HydrophobicContact CD1-CB 4.43Å; L401-F424 HydrophobicContact CD2-CB 3.84Å; L401-F424 HydrophobicContact CD2-CG 4.2Å; L401-F424 HydrophobicContact CG-CB 4.43Å; L401-W426 HydrophobicContact CD1-CE3 4.48Å; L401-L430 HydrophobicContact CD1-CD1 4.17Å
402Y98.1Very high97.7Very high140 Ų14065.6 Ų65.655%0.54935%0.347SS..Hα-helixtrans-61.9-52.2176179.3-90.7000111.8Y398 R399 Y404 N405 A406Y398-Y402 VanDerWaalsContact O-CB 3.25Å; Y398-Y402 WeakPolarHBondContact O-CB 3.16Å; Y398-Y402 PolarHBondContact O-N 2.86Å; R399-Y402 PolarHBondContact O-N 3.3Å; Y402-Y404 VanDerWaalsContact C-N 3.32Å; Y402-Y404 PolarHBondContact O-N 2.79Å; Y402-N405 PolarHBondContact O-N 2.92Å; Y402-N405 VanDerWaalsContact O-N 3.1Å; Y402-A406 PolarHBondContact O-N 3.29Å
403D98.1Very high97.7Very high91 Ų9164.6 Ų64.649%0.48734%0.341SS..Hα-helixtrans-61.7-41.1-179.3-68.3-16.5000110.8R399 N405 A406 S407R399-D403 VanDerWaalsContact O-CB 3.29Å; R399-D403 WeakPolarHBondContact O-CB 3.25Å; R399-D403 PolarHBondContact O-N 2.88Å; D403-N405 VanDerWaalsContact C-N 3.35Å; D403-N405 PolarHBondContact O-N 2.94Å; D403-A406 PolarHBondContact O-N 2.87Å; D403-S407 WeakPolarHBondContact O-CB 3.45Å; D403-S407 PolarHBondContact O-N 3.38Å; D403-S407 PolarHBondContact O-OG 2.91Å
404Y98.5Very high97.8Very high1 Ų164.9 Ų64.90%0.00435%0.347CS..Hα-helixtrans-58.4-45.8173.7177.1-84.5000111.7I312 T400 Y402 S407 A408 F420 V422 F424I312-Y404 HydrophobicContact CG2-CD2 3.7Å; I312-Y404 HydrophobicContact CG2-CE2 3.49Å; I312-Y404 VanDerWaalsContact CG2-CE2 3.49Å; T400-Y404 WeakPolarHBondContact O-CB 3.31Å; T400-Y404 PolarHBondContact O-N 3.45Å; T400-Y404 VanDerWaalsContact O-N 3.14Å; Y402-Y404 VanDerWaalsContact C-N 3.32Å; Y402-Y404 PolarHBondContact O-N 2.79Å; Y404-S407 PolarHBondContact O-N 2.83Å; Y404-A408 WeakPolarHBondContact O-CB 3.33Å; Y404-A408 PolarHBondContact O-N 3.43Å; Y404-F420 HydrophobicContact CD2-CD1 4.16Å; Y404-F420 HydrophobicContact CD2-CE1 4.12Å; Y404-F420 HydrophobicContact CE1-CD1 4.16Å; Y404-F420 AromaticContact CE2-CD1 3.63Å; Y404-F420 HydrophobicContact CE2-CD1 3.63Å; Y404-F420 AromaticContact CE2-CE1 3.92Å; Y404-F420 HydrophobicContact CE2-CE1 3.92Å; Y404-F420 AromaticContact CZ-CD1 3.62Å; Y404-V422 VanDerWaalsContact CE1-O 3.24Å; Y404-V422 WeakPolarHBondContact CE1-O 3.42Å; Y404-V422 PolarHBondContact OH-O 3.41Å; Y404-V422 VanDerWaalsContact OH-O 3.13Å; Y404-F424 AromaticContact CD1-CD2 3.7Å; Y404-F424 HydrophobicContact CD1-CD2 3.7Å; Y404-F424 HydrophobicContact CD1-CE2 4.25Å; Y404-F424 AromaticContact CE1-CD2 3.61Å; Y404-F424 HydrophobicContact CE1-CD2 3.61Å; Y404-F424 AromaticContact CE1-CE2 3.82Å; Y404-F424 HydrophobicContact CE1-CE2 3.82Å; Y404-F424 HydrophobicContact CG-CD2 4.41Å; Y404-F424 AromaticContact CZ-CE2 3.98Å
405N98.5Very high97.8Very high40 Ų4065.3 Ų65.321%0.21434%0.344CS..Hα-helixtrans-68.3-37.9179-69-17.1000112.6L401 Y402 D403 S407 A408 A409 T423 F424L401-N405 VanDerWaalsContact O-CG 3.25Å; L401-N405 PolarHBondContact O-N 3.41Å; L401-N405 VanDerWaalsContact O-N 3.09Å; L401-N405 PolarHBondContact O-ND2 3.49Å; Y402-N405 PolarHBondContact O-N 2.92Å; Y402-N405 VanDerWaalsContact O-N 3.1Å; D403-N405 VanDerWaalsContact C-N 3.35Å; D403-N405 PolarHBondContact O-N 2.94Å; N405-S407 VanDerWaalsContact C-N 3.35Å; N405-A408 WeakPolarHBondContact O-CB 3.32Å; N405-A408 PolarHBondContact O-N 2.96Å; N405-A409 PolarHBondContact O-N 3.21Å; N405-T423 WeakPolarHBondContact OD1-CA 3.4Å; N405-T423 VanDerWaalsContact OD1-CB 3.22Å; N405-T423 WeakPolarHBondContact OD1-CB 3.48Å; N405-F424 PolarHBondContact ND2-O 3.03Å; N405-F424 PolarHBondContact OD1-N 2.98Å
406A98.3Very high97.7Very high47 Ų4762.5 Ų62.539%0.38834%0.341SS..Hα-helixtrans-62-44.5174.800000110.7Y402 D403 A409Y402-A406 PolarHBondContact O-N 3.29Å; D403-A406 PolarHBondContact O-N 2.87Å; A406-A409 WeakPolarHBondContact O-CB 3.49Å; A406-A409 PolarHBondContact O-N 3.31Å
407S98.4Very high97.7Very high23 Ų2361.3 Ų61.316%0.16133%0.331CS..Hα-helixtrans-64.2-37.2172.6-76.70000113.4D403 Y404 N405 A409 V410 N411 H412 D413D403-S407 WeakPolarHBondContact O-CB 3.45Å; D403-S407 PolarHBondContact O-N 3.38Å; D403-S407 PolarHBondContact O-OG 2.91Å; Y404-S407 PolarHBondContact O-N 2.83Å; N405-S407 VanDerWaalsContact C-N 3.35Å; S407-A409 VanDerWaalsContact C-N 3.28Å; S407-A409 PolarHBondContact O-N 3.46Å; S407-V410 CarbonylContact O-C 3.36Å; S407-V410 WeakPolarHBondContact O-CG2 3.33Å; S407-V410 PolarHBondContact O-N 3.33Å; S407-N411 WeakPolarHBondContact O-CA 3.35Å; S407-N411 PolarHBondContact O-N 2.79Å; S407-H412 WeakPolarHBondContact CA-O 3.23Å; S407-H412 WeakPolarHBondContact CB-O 3.25Å; S407-H412 PolarHBondContact O-N 3.16Å; S407-H412 VanDerWaalsContact O-N 3.15Å; S407-H412 PolarHBondContact OG-O 2.83Å; S407-H412 VanDerWaalsContact OG-O 3.05Å; S407-D413 WeakPolarHBondContact OG-CA 3.4Å; S407-D413 VanDerWaalsContact OG-CB 3.22Å; S407-D413 WeakPolarHBondContact OG-CB 3.44Å
408A98.1Very high97.7Very high14 Ų1465.4 Ų65.412%0.11636%0.356CS..Hα-helixtrans-61.9-36.3175.500000112Y404 N405 V410 N411 F420 T423Y404-A408 WeakPolarHBondContact O-CB 3.33Å; Y404-A408 PolarHBondContact O-N 3.43Å; N405-A408 WeakPolarHBondContact O-CB 3.32Å; N405-A408 PolarHBondContact O-N 2.96Å; A408-V410 PolarHBondContact O-N 2.91Å; A408-N411 PolarHBondContact O-N 2.92Å; A408-F420 HydrophobicContact CB-CB 3.57Å; A408-F420 HydrophobicContact CB-CD1 3.77Å; A408-F420 HydrophobicContact CB-CG 3.76Å; A408-T423 HydrophobicContact CB-CG2 4.23Å
409A97.9Very high97.6Very high85 Ų8562.1 Ų62.170%0.70235%0.347SS*.Hα-helixtrans-65.1-26.717800000113.5N405 A406 S407N405-A409 PolarHBondContact O-N 3.21Å; A406-A409 WeakPolarHBondContact O-CB 3.49Å; A406-A409 PolarHBondContact O-N 3.31Å; S407-A409 VanDerWaalsContact C-N 3.28Å; S407-A409 PolarHBondContact O-N 3.46Å
410V97.5Very high97.5Very high107 Ų10756.4 Ų56.465%0.64833%0.326SS*.Hα-helixtrans-110.52.9179.3-59.30000113.5S407 A408 H412S407-V410 CarbonylContact O-C 3.36Å; S407-V410 WeakPolarHBondContact O-CG2 3.33Å; S407-V410 PolarHBondContact O-N 3.33Å; A408-V410 PolarHBondContact O-N 2.91Å; V410-H412 PolarHBondContact O-N 3.16Å
411N95.8Very high97.4Very high95 Ų9557.8 Ų57.851%0.50834%0.336SS..THydrogen-bonded Turntrans51.836.5-176.1-63.4-62.6000114.4S407 A408 T418S407-N411 WeakPolarHBondContact O-CA 3.35Å; S407-N411 PolarHBondContact O-N 2.79Å; A408-N411 PolarHBondContact O-N 2.92Å; N411-T418 WeakPolarHBondContact O-CA 3.18Å
412H97.3Very high97.4Very high108 Ų10858 Ų5850%0.534%0.337SS..  trans-155.4137176.8-166.165.5000111.8S407 V410 K417S407-H412 WeakPolarHBondContact CA-O 3.23Å; S407-H412 WeakPolarHBondContact CB-O 3.25Å; S407-H412 PolarHBondContact O-N 3.16Å; S407-H412 VanDerWaalsContact O-N 3.15Å; S407-H412 PolarHBondContact OG-O 2.83Å; S407-H412 VanDerWaalsContact OG-O 3.05Å; V410-H412 PolarHBondContact O-N 3.16Å; H412-K417 VanDerWaalsContact CA-O 3.28Å; H412-K417 WeakPolarHBondContact CA-O 3.47Å
413D97.4Very high97.4Very high5 Ų554.4 Ų54.43%0.02733%0.329CS..  trans-126.9173.9167.972.415.3000112.4R320 S407 Y415 G416 K417 F420R320-D413 IonicContact CZ-OD2 2.89Å; R320-D413 VanDerWaalsContact CZ-OD2 3.3Å; R320-D413 IonicContact NH1-OD2 2.63Å; R320-D413 PolarHBondContact NH1-OD2 3.21Å; R320-D413 IonicContact NH2-OD2 2.76Å; R320-D413 PolarHBondContact NH2-OD2 2.98Å; S407-D413 WeakPolarHBondContact OG-CA 3.4Å; S407-D413 VanDerWaalsContact OG-CB 3.22Å; S407-D413 WeakPolarHBondContact OG-CB 3.44Å; D413-Y415 PolarHBondContact O-N 3.25Å; D413-Y415 WeakPolarHBondContact OD1-CA 3.46Å; D413-Y415 WeakPolarHBondContact OD1-CB 3.45Å; D413-Y415 PolarHBondContact OD1-N 3.25Å; D413-G416 PolarHBondContact O-N 3.48Å; D413-G416 PolarHBondContact OD1-N 3.01Å; D413-K417 VanDerWaalsContact CG-CB 3.43Å; D413-K417 PolarHBondContact N-O 2.74Å; D413-K417 WeakPolarHBondContact OD1-CB 3.11Å; D413-K417 PolarHBondContact OD1-N 2.83Å; D413-K417 VanDerWaalsContact OD2-CB 3.29Å; D413-K417 WeakPolarHBondContact OD2-CB 3.16Å; D413-F420 HydrophobicContact CB-CZ 4.04Å
414T96.6Very high97.4Very high136 Ų13650.1 Ų50.183%0.83431%0.306SS*.THydrogen-bonded Turntrans-67.3-12.7179.752.60000114G416T414-G416 VanDerWaalsContact C-N 3.3Å
415Y97.2Very high97.4Very high86 Ų8654.9 Ų54.934%0.33733%0.332SS..THydrogen-bonded Turntrans-90.85.4172.8-48.2-70.3000112R320 D413 K417R320-Y415 HydrophobicContact CB-CE2 3.91Å; R320-Y415 PolarHBondContact O-OH 3.24Å; D413-Y415 PolarHBondContact O-N 3.25Å; D413-Y415 WeakPolarHBondContact OD1-CA 3.46Å; D413-Y415 WeakPolarHBondContact OD1-CB 3.45Å; D413-Y415 PolarHBondContact OD1-N 3.25Å; Y415-K417 PolarHBondContact O-N 3.35Å
416G96.3Very high97.3Very high38 Ų3856.3 Ų56.339%0.39233%0.334SS..  trans72.116.1-177.400000113.7D413 T414D413-G416 PolarHBondContact O-N 3.48Å; D413-G416 PolarHBondContact OD1-N 3.01Å; T414-G416 VanDerWaalsContact C-N 3.3Å
417K97.4Very high97.3Very high2 Ų260.4 Ų60.41%0.00935%0.35CS..  trans-69.8133.9173.7-173.3173.4178.353.50109.6N323 E324 H412 D413 Y415 V419 F420N323-K417 HydrophobicContact CB-CB 4.06Å; N323-K417 WeakPolarHBondContact OD1-CG 3.45Å; E324-K417 IonicContact OE2-NZ 3.55Å; H412-K417 VanDerWaalsContact CA-O 3.28Å; H412-K417 WeakPolarHBondContact CA-O 3.47Å; D413-K417 VanDerWaalsContact CG-CB 3.43Å; D413-K417 PolarHBondContact N-O 2.74Å; D413-K417 WeakPolarHBondContact OD1-CB 3.11Å; D413-K417 PolarHBondContact OD1-N 2.83Å; D413-K417 VanDerWaalsContact OD2-CB 3.29Å; D413-K417 WeakPolarHBondContact OD2-CB 3.16Å; Y415-K417 PolarHBondContact O-N 3.35Å; K417-V419 WeakPolarHBondContact CE-O 3.44Å; K417-V419 PolarHBondContact NZ-O 3.04Å; K417-F420 HydrophobicContact CB-CE2 4.29Å; K417-F420 HydrophobicContact CB-CZ 3.86Å; K417-F420 HydrophobicContact CD-CD1 4.34Å; K417-F420 HydrophobicContact CD-CE1 3.77Å; K417-F420 HydrophobicContact CD-CE2 4.48Å; K417-F420 HydrophobicContact CD-CZ 3.84Å; K417-F420 HydrophobicContact CG-CE1 4.16Å; K417-F420 HydrophobicContact CG-CE2 3.97Å; K417-F420 HydrophobicContact CG-CZ 3.72Å; K417-F420 WeakPolarHBondContact O-CE2 3.23Å
418T96.4Very high97.3Very high87 Ų8761 Ų6153%0.53435%0.35SS..  trans-122.31.4178.755.40000113.7N411N411-T418 WeakPolarHBondContact O-CA 3.18Å
419V96.3Very high97.3Very high40 Ų4062.7 Ų62.724%0.24236%0.359CS..  trans-124.8111-173.2177.20000109.2I138 L325 K417 P421I138-V419 HydrophobicContact CD1-CG2 4.2Å; I138-V419 HydrophobicContact CG2-CG1 3.82Å; L325-V419 HydrophobicContact CD1-CB 3.97Å; L325-V419 HydrophobicContact CD1-CG1 3.89Å; K417-V419 WeakPolarHBondContact CE-O 3.44Å; K417-V419 PolarHBondContact NZ-O 3.04Å; V419-P421 HydrophobicContact CG1-CG 3.93Å
420F97.4Very high97.4Very high23 Ų2358.6 Ų58.610%0.10133%0.325CS..  trans-127.180.9-177.8-60.8-97.5000110Y404 A408 D413 K417 V422Y404-F420 HydrophobicContact CD2-CD1 4.16Å; Y404-F420 HydrophobicContact CD2-CE1 4.12Å; Y404-F420 HydrophobicContact CE1-CD1 4.16Å; Y404-F420 AromaticContact CE2-CD1 3.63Å; Y404-F420 HydrophobicContact CE2-CD1 3.63Å; Y404-F420 AromaticContact CE2-CE1 3.92Å; Y404-F420 HydrophobicContact CE2-CE1 3.92Å; Y404-F420 AromaticContact CZ-CD1 3.62Å; A408-F420 HydrophobicContact CB-CB 3.57Å; A408-F420 HydrophobicContact CB-CD1 3.77Å; A408-F420 HydrophobicContact CB-CG 3.76Å; D413-F420 HydrophobicContact CB-CZ 4.04Å; K417-F420 HydrophobicContact CB-CE2 4.29Å; K417-F420 HydrophobicContact CB-CZ 3.86Å; K417-F420 HydrophobicContact CD-CD1 4.34Å; K417-F420 HydrophobicContact CD-CE1 3.77Å; K417-F420 HydrophobicContact CD-CE2 4.48Å; K417-F420 HydrophobicContact CD-CZ 3.84Å; K417-F420 HydrophobicContact CG-CE1 4.16Å; K417-F420 HydrophobicContact CG-CE2 3.97Å; K417-F420 HydrophobicContact CG-CZ 3.72Å; K417-F420 WeakPolarHBondContact O-CE2 3.23Å; F420-V422 PolarHBondContact O-N 3.06Å
421P96Very high97.4Very high42 Ų4254.2 Ų54.227%0.27330%0.297SS..  trans-73.8-10-172.1-15.831000114.6K361 V419K361-P421 PolarHBondContact NZ-O 3.38Å; V419-P421 HydrophobicContact CG1-CG 3.93Å
422V97.7Very high97.5Very high7 Ų749.9 Ų49.94%0.04227%0.274CS..  trans-148.1165.8179.5-58.10000109.4E357 I358 Y404 F420 F424E357-V422 HydrophobicContact CB-CG1 4.07Å; E357-V422 HydrophobicContact CG-CG1 3.92Å; I358-V422 HydrophobicContact CD1-CG2 3.78Å; I358-V422 HydrophobicContact CG1-CG1 4Å; I358-V422 HydrophobicContact CG1-CG2 3.93Å; Y404-V422 VanDerWaalsContact CE1-O 3.24Å; Y404-V422 WeakPolarHBondContact CE1-O 3.42Å; Y404-V422 PolarHBondContact OH-O 3.41Å; Y404-V422 VanDerWaalsContact OH-O 3.13Å; F420-V422 PolarHBondContact O-N 3.06Å; V422-F424 HydrophobicContact CG2-CE2 4.07Å; V422-F424 HydrophobicContact CG2-CZ 4.29Å
423T98Very high97.6Very high65 Ų6544.8 Ų44.840%0.39925%0.251SS..  trans-112.9167.8164.951.10000110.3N355 N405 A408N355-T423 PolarHBondContact ND2-O 3.19Å; N405-T423 WeakPolarHBondContact OD1-CA 3.4Å; N405-T423 VanDerWaalsContact OD1-CB 3.22Å; N405-T423 WeakPolarHBondContact OD1-CB 3.48Å; A408-T423 HydrophobicContact CB-CG2 4.23Å
424F98.6Very high97.7Very high1 Ų147.7 Ų47.70%0.00426%0.261CS..  trans-122.9118.9177.1-69-90.4000111.7G310 I312 V353 N355 I358 L401 Y404 N405 V422 E428 L430G310-F424 WeakPolarHBondContact O-CE2 3.49Å; G310-F424 WeakPolarHBondContact O-CZ 3.43Å; I312-F424 HydrophobicContact CD1-CD2 4.35Å; I312-F424 HydrophobicContact CD1-CE2 4.16Å; I312-F424 HydrophobicContact CD1-CZ 4.35Å; I312-F424 HydrophobicContact CG1-CE2 4.25Å; I312-F424 HydrophobicContact CG1-CZ 4.12Å; I312-F424 HydrophobicContact CG2-CE2 3.79Å; I312-F424 HydrophobicContact CG2-CZ 4.26Å; V353-F424 HydrophobicContact CG1-CE1 4.38Å; N355-F424 HydrophobicContact CB-CD1 4.14Å; N355-F424 HydrophobicContact CB-CE1 4.08Å; I358-F424 HydrophobicContact CD1-CE1 4.28Å; I358-F424 HydrophobicContact CD1-CZ 3.83Å; L401-F424 HydrophobicContact CB-CB 4.39Å; L401-F424 HydrophobicContact CD1-CB 4.43Å; L401-F424 HydrophobicContact CD2-CB 3.84Å; L401-F424 HydrophobicContact CD2-CG 4.2Å; L401-F424 HydrophobicContact CG-CB 4.43Å; Y404-F424 AromaticContact CD1-CD2 3.7Å; Y404-F424 HydrophobicContact CD1-CD2 3.7Å; Y404-F424 HydrophobicContact CD1-CE2 4.25Å; Y404-F424 AromaticContact CE1-CD2 3.61Å; Y404-F424 HydrophobicContact CE1-CD2 3.61Å; Y404-F424 AromaticContact CE1-CE2 3.82Å; Y404-F424 HydrophobicContact CE1-CE2 3.82Å; Y404-F424 HydrophobicContact CG-CD2 4.41Å; Y404-F424 AromaticContact CZ-CE2 3.98Å; N405-F424 PolarHBondContact ND2-O 3.03Å; N405-F424 PolarHBondContact OD1-N 2.98Å; V422-F424 HydrophobicContact CG2-CE2 4.07Å; V422-F424 HydrophobicContact CG2-CZ 4.29Å; F424-E428 WeakPolarHBondContact CA-OE1 3.34Å; F424-L430 HydrophobicContact CD1-CD2 3.76Å; F424-L430 HydrophobicContact CE1-CD2 4.36Å
425L97.9Very high97.8Very high102 Ų10241.2 Ų41.253%0.53422%0.222SC..  trans-90.7147.7179.2-57.9179.5000111.5N427 E428L425-N427 VanDerWaalsContact C-N 3.31Å; L425-N427 PolarHBondContact O-N 2.93Å; L425-E428 HydrophobicContact CB-CB 4.13Å; L425-E428 HydrophobicContact CB-CG 4.11Å; L425-E428 PolarHBondContact N-OE1 3.23Å; L425-E428 WeakPolarHBondContact O-CG 3.42Å
426W97.9Very high97.8Very high69 Ų6937.2 Ų37.226%0.26121%0.206SC..THydrogen-bonded Turntrans-62.6-38.3177.8-177.7-106.9000112.7N382 G383 N394 I397 Y398 L401N382-W426 WeakPolarHBondContact CA-O 3.31Å; N382-W426 VanDerWaalsContact CB-O 3.26Å; N382-W426 WeakPolarHBondContact CB-O 3.34Å; G383-W426 VanDerWaalsContact C-CH2 3.49Å; G383-W426 PolarHBondContact N-O 2.99Å; N394-W426 HydrophobicContact CB-CH2 4.19Å; I397-W426 HydrophobicContact CB-CZ3 4.27Å; I397-W426 HydrophobicContact CG2-CZ3 3.96Å; Y398-W426 VanDerWaalsContact CA-CZ3 3.46Å; Y398-W426 AromaticContact CD2-CD2 3.82Å; Y398-W426 HydrophobicContact CD2-CD2 3.82Å; Y398-W426 AromaticContact CD2-CE3 3.64Å; Y398-W426 HydrophobicContact CD2-CE3 3.64Å; Y398-W426 HydrophobicContact CD2-CG 4.28Å; Y398-W426 HydrophobicContact CD2-CZ3 4.04Å; Y398-W426 HydrophobicContact CG-CE3 4.32Å; Y398-W426 HydrophobicContact CG-CZ3 4.33Å; L401-W426 HydrophobicContact CD1-CE3 4.48Å
427N98Very high98Very high134 Ų13435.6 Ų35.672%0.71719%0.188SC*.THydrogen-bonded Turntrans-10124.6-174.9-68.1-32.2000113.8L425L425-N427 VanDerWaalsContact C-N 3.31Å; L425-N427 PolarHBondContact O-N 2.93Å
428E97.9Very high98Very high34 Ų3435.5 Ų35.516%0.15919%0.188CC..SBendtrans-102.6160.217377.6177.1137.800112.7N355 A381 N382 F424 L425 L430N355-E428 WeakPolarHBondContact CB-OE2 3.25Å; N355-E428 PolarHBondContact ND2-OE1 2.91Å; N355-E428 PolarHBondContact ND2-OE2 2.95Å; A381-E428 CarbonylContact C-O 3.45Å; A381-E428 CarbonylContact O-C 3.55Å; N382-E428 WeakPolarHBondContact CA-O 3.46Å; F424-E428 WeakPolarHBondContact CA-OE1 3.34Å; L425-E428 HydrophobicContact CB-CB 4.13Å; L425-E428 HydrophobicContact CB-CG 4.11Å; L425-E428 PolarHBondContact N-OE1 3.23Å; L425-E428 WeakPolarHBondContact O-CG 3.42Å; E428-L430 HydrophobicContact CG-CD2 3.78Å; E428-L430 HydrophobicContact CG-CG 4.38Å; E428-L430 PolarHBondContact O-N 2.91Å
429T98.4Very high98.1Very high50 Ų5031.4 Ų31.431%0.30716%0.163SC..  trans-68.1127170.4-52.80000110.5V380 Y431V380-T429 WeakPolarHBondContact O-CA 3.35Å; T429-Y431 HydrophobicContact CG2-CE1 4.45Å; T429-Y431 HydrophobicContact CG2-CE2 4.35Å
430L98.7Very high98.2Very high0 Ų030.7 Ų30.70%016%0.157CC..EExtended strand (participates in β ladder)trans-114.7154.5175-56.7174.5000109.6V353 N355 D379 V380 L386 L401 F424 E428V353-L430 HydrophobicContact CG1-CB 4.33Å; V353-L430 HydrophobicContact CG1-CD1 4.46Å; N355-L430 HydrophobicContact CB-CD2 3.99Å; D379-L430 WeakPolarHBondContact CA-O 3.4Å; V380-L430 HydrophobicContact CG2-CB 3.82Å; V380-L430 PolarHBondContact N-O 2.91Å; V380-L430 PolarHBondContact O-N 3.03Å; L386-L430 HydrophobicContact CB-CD1 4.39Å; L386-L430 HydrophobicContact CD2-CD1 3.73Å; L401-L430 HydrophobicContact CD1-CD1 4.17Å; F424-L430 HydrophobicContact CD1-CD2 3.76Å; F424-L430 HydrophobicContact CE1-CD2 4.36Å; E428-L430 HydrophobicContact CG-CD2 3.78Å; E428-L430 HydrophobicContact CG-CG 4.38Å; E428-L430 PolarHBondContact O-N 2.91Å
431Y98.7Very high98.2Very high15 Ų1529.7 Ų29.76%0.05915%0.153CC..EExtended strand (participates in β ladder)trans-122.9128.5174.4-51.6-93.4000108.5V353 V354 N356 F367 W371 K378 D379 T429V353-Y431 WeakPolarHBondContact CA-O 3.38Å; V354-Y431 HydrophobicContact CG2-CD2 4.23Å; V354-Y431 HydrophobicContact CG2-CG 4.42Å; V354-Y431 PolarHBondContact N-O 2.85Å; V354-Y431 PolarHBondContact O-N 3.45Å; N356-Y431 VanDerWaalsContact OD1-CE2 3.24Å; N356-Y431 WeakPolarHBondContact OD1-CE2 3.42Å; N356-Y431 PolarHBondContact OD1-OH 3.25Å; F367-Y431 AromaticContact CE1-CD1 3.76Å; F367-Y431 HydrophobicContact CE1-CD1 3.76Å; F367-Y431 AromaticContact CE1-CD2 3.94Å; F367-Y431 HydrophobicContact CE1-CD2 3.94Å; F367-Y431 AromaticContact CE1-CE1 3.86Å; F367-Y431 HydrophobicContact CE1-CE1 3.86Å; F367-Y431 HydrophobicContact CE1-CE2 4.04Å; F367-Y431 AromaticContact CE1-CG 3.8Å; F367-Y431 HydrophobicContact CE1-CG 3.8Å; F367-Y431 AromaticContact CZ-CD1 3.87Å; F367-Y431 HydrophobicContact CZ-CD1 3.87Å; F367-Y431 AromaticContact CZ-CD2 3.77Å; F367-Y431 HydrophobicContact CZ-CD2 3.77Å; F367-Y431 HydrophobicContact CZ-CE1 4.42Å; F367-Y431 HydrophobicContact CZ-CE2 4.34Å; F367-Y431 AromaticContact CZ-CG 3.52Å; F367-Y431 HydrophobicContact CZ-CG 3.52Å; W371-Y431 HydrophobicContact CD2-CD1 4.09Å; W371-Y431 AromaticContact CD2-CE1 3.81Å; W371-Y431 HydrophobicContact CD2-CE1 3.81Å; W371-Y431 AromaticContact CE2-CD1 3.98Å; W371-Y431 AromaticContact CE2-CE1 3.68Å; W371-Y431 AromaticContact CE3-CE1 3.87Å; W371-Y431 HydrophobicContact CE3-CE1 3.87Å; W371-Y431 HydrophobicContact CG-CD1 4.39Å; W371-Y431 AromaticContact CH2-CE1 3.69Å; W371-Y431 HydrophobicContact CH2-CE1 3.69Å; W371-Y431 HydrophobicContact CZ2-CD1 4.31Å; W371-Y431 AromaticContact CZ2-CE1 3.63Å; W371-Y431 HydrophobicContact CZ2-CE1 3.63Å; W371-Y431 AromaticContact CZ3-CE1 3.82Å; W371-Y431 HydrophobicContact CZ3-CE1 3.82Å; K378-Y431 CarbonylContact O-C 3.52Å; K378-Y431 WeakPolarHBondContact O-CA 3.49Å; D379-Y431 HydrophobicContact CB-CD1 3.83Å; D379-Y431 HydrophobicContact CB-CE1 3.88Å; T429-Y431 HydrophobicContact CG2-CE1 4.45Å; T429-Y431 HydrophobicContact CG2-CE2 4.35Å
432V98.6Very high98.3Very high3 Ų327.7 Ų27.72%0.01814%0.14CC..EExtended strand (participates in β ladder)trans-120131.6-178.158.30000110.5F351 L352 V353 F377 K378 V380 L386 H389F351-V432 HydrophobicContact CB-CG2 4Å; F351-V432 HydrophobicContact CD1-CG2 3.92Å; F351-V432 HydrophobicContact CG-CG2 4.41Å; L352-V432 WeakPolarHBondContact O-CA 3.21Å; V353-V432 HydrophobicContact CG2-CB 4.46Å; V353-V432 HydrophobicContact CG2-CG2 4.21Å; F377-V432 CarbonylContact C-O 3.55Å; F377-V432 WeakPolarHBondContact CA-O 3.42Å; K378-V432 HydrophobicContact CB-CG1 4.19Å; K378-V432 PolarHBondContact N-O 2.08Å; K378-V432 PolarHBondContact O-N 2.93Å; V380-V432 HydrophobicContact CG1-CG1 4.48Å; L386-V432 HydrophobicContact CD1-CB 3.89Å; L386-V432 HydrophobicContact CD1-CG1 4.09Å; L386-V432 HydrophobicContact CD1-CG2 4.13Å; H389-V432 VanDerWaalsContact CD2-CG1 3.4Å; H389-V432 WeakPolarHBondContact CD2-CG1 3.48Å
433A98.6Very high98.3Very high2 Ų227.5 Ų27.52%0.01714%0.138CC..EExtended strand (participates in β ladder)trans-125.2149.2173.300000110.2F288 F351 L352 F376 F377F288-A433 HydrophobicContact CD1-CB 3.94Å; F288-A433 HydrophobicContact CE1-CB 3.74Å; F351-A433 CarbonylContact C-O 3.5Å; F351-A433 WeakPolarHBondContact CA-O 3.34Å; L352-A433 PolarHBondContact N-O 3.45Å; L352-A433 PolarHBondContact O-N 2.88Å; F376-A433 WeakPolarHBondContact O-CA 3.37Å; F376-A433 WeakPolarHBondContact O-CB 3.31Å; F377-A433 HydrophobicContact CD1-CB 3.55Å; F377-A433 HydrophobicContact CD2-CB 4.41Å; F377-A433 HydrophobicContact CE1-CB 3.51Å; F377-A433 HydrophobicContact CE2-CB 4.38Å; F377-A433 HydrophobicContact CG-CB 4.01Å; F377-A433 HydrophobicContact CZ-CB 3.95Å
434R98.6Very high98.3Very high66 Ų6624.4 Ų24.425%0.24912%0.119CC..EExtended strand (participates in β ladder)trans-87132.4170.7-67.4173.960-160.9-5109.3V289 D342 V345 V349 F351V289-R434 HydrophobicContact CB-CB 3.91Å; V289-R434 HydrophobicContact CG2-CB 4.3Å; V289-R434 PolarHBondContact N-O 3.12Å; D342-R434 IonicContact OD2-CZ 3.65Å; D342-R434 IonicContact OD2-NH1 3.39Å; D342-R434 IonicContact OD2-NH2 3.96Å; D342-R434 PolarHBondContact OD2-NH2 3.2Å; V345-R434 VanDerWaalsContact CG2-NH2 3.29Å; V349-R434 HydrophobicContact CG1-CB 3.92Å; V349-R434 HydrophobicContact CG1-CG 4.24Å; F351-R434 HydrophobicContact CD1-CG 4.03Å; F351-R434 HydrophobicContact CE1-CG 3.84Å
435V98.8Very high98.3Very high0 Ų024.3 Ų24.30%012%0.119CC..EExtended strand (participates in β ladder)trans-133.8149-179.1-63.20000111.4T286 G287 F288 A302 L313 V349 A350 L352T286-V435 HydrophobicContact CG2-CB 4.2Å; T286-V435 HydrophobicContact CG2-CG2 3.88Å; G287-V435 CarbonylContact O-C 3.15Å; G287-V435 VanDerWaalsContact O-CA 3.25Å; G287-V435 WeakPolarHBondContact O-CA 3.13Å; F288-V435 HydrophobicContact CD1-CG1 4.15Å; A302-V435 HydrophobicContact CB-CG1 4.17Å; L313-V435 HydrophobicContact CD2-CG2 3.92Å; V349-V435 CarbonylContact C-O 3.6Å; V349-V435 WeakPolarHBondContact CA-O 3.4Å; A350-V435 HydrophobicContact CB-CG2 4.04Å; A350-V435 PolarHBondContact N-O 3.34Å; A350-V435 PolarHBondContact O-N 3.46Å; L352-V435 HydrophobicContact CB-CG1 3.96Å; L352-V435 HydrophobicContact CB-CG2 4.18Å; L352-V435 HydrophobicContact CD2-CG1 4.33Å
436T98.7Very high98.3Very high2 Ų219.5 Ų19.51%0.0129%0.093CC..EExtended strand (participates in β ladder)trans-138.1154.6179.1-175.60000110.1P253 P285 G287 V289 K299 V345 S348 V438P253-T436 HydrophobicContact CG-CG2 4.26Å; P285-T436 CarbonylContact O-C 3.57Å; G287-T436 PolarHBondContact N-O 3.1Å; G287-T436 PolarHBondContact O-N 3.46Å; V289-T436 HydrophobicContact CG2-CG2 3.9Å; K299-T436 HydrophobicContact CD-CG2 3.7Å; V345-T436 HydrophobicContact CG1-CG2 3.81Å; S348-T436 PolarHBondContact O-OG1 2.96Å; T436-V438 HydrophobicContact CG2-CG1 4.45Å
437P98.5Very high98.4Very high3 Ų317.4 Ų17.42%0.0199%0.088CC..EExtended strand (participates in β ladder)trans-57.1141169.6-27.237.4000112.3F252 H284 T332 I335 S348F252-P437 HydrophobicContact CE1-CB 4.26Å; H284-P437 WeakPolarHBondContact O-CA 3.29Å; T332-P437 HydrophobicContact CG2-CB 3.7Å; T332-P437 HydrophobicContact CG2-CG 3.84Å; I335-P437 HydrophobicContact CB-CG 4.26Å; I335-P437 HydrophobicContact CD1-CG 4.47Å; I335-P437 HydrophobicContact CG2-CG 3.99Å; S348-P437 WeakPolarHBondContact O-CD 3.26Å
438V98.4Very high98.4Very high0 Ų011.3 Ų11.30%06%0.056CC..EExtended strand (participates in β ladder)trans-140.8140.2-177.5-75.80000111.1P253 T255 L283 H284 K299 T436 H440P253-V438 HydrophobicContact CB-CG1 4.07Å; P253-V438 HydrophobicContact CG-CG1 3.79Å; P253-V438 CarbonylContact O-C 3.58Å; P253-V438 WeakPolarHBondContact O-CA 3.32Å; T255-V438 HydrophobicContact CG2-CB 4.05Å; T255-V438 HydrophobicContact CG2-CG2 3.55Å; L283-V438 CarbonylContact C-O 3.15Å; L283-V438 VanDerWaalsContact CA-O 3.31Å; L283-V438 WeakPolarHBondContact CA-O 3.37Å; H284-V438 HydrophobicContact CB-CG2 4.03Å; H284-V438 PolarHBondContact N-O 3.39Å; H284-V438 WeakPolarHBondContact O-CG2 3.39Å; H284-V438 PolarHBondContact O-N 3.21Å; K299-V438 HydrophobicContact CB-CG1 4.08Å; K299-V438 HydrophobicContact CD-CG1 3.97Å; K299-V438 HydrophobicContact CG-CG1 4.44Å; T436-V438 HydrophobicContact CG2-CG1 4.45Å; V438-H440 PolarHBondContact O-N 3.47Å
439I98.2Very high98.4Very high2 Ų211.2 Ų11.21%0.016%0.056CC..EExtended strand (participates in β ladder)trans-61124.4168.8-54.8175.3000108.4I242 L249 F252 P253 T254 T255 N256 L281 L283I242-I439 HydrophobicContact CD1-CD1 4.28Å; L249-I439 HydrophobicContact CB-CD1 4Å; F252-I439 HydrophobicContact CB-CD1 4.02Å; F252-I439 HydrophobicContact CB-CG1 3.82Å; P253-I439 PolarHBondContact O-N 2.95Å; T254-I439 CarbonylContact C-O 3.59Å; T254-I439 VanDerWaalsContact CA-O 3.26Å; T254-I439 WeakPolarHBondContact CA-O 3.11Å; T254-I439 PolarHBondContact OG1-O 2.8Å; T254-I439 VanDerWaalsContact OG1-O 3.08Å; T255-I439 PolarHBondContact N-O 3.18Å; N256-I439 PolarHBondContact ND2-O 3.28Å; L281-I439 HydrophobicContact CB-CG2 4.13Å; L281-I439 HydrophobicContact CD2-CG2 3.73Å; L283-I439 HydrophobicContact CD2-CB 4.46Å; L283-I439 HydrophobicContact CD2-CG1 3.87Å
440H97.8Very high98.4Very high25 Ų2511.4 Ų11.412%0.1166%0.058CC..EExtended strand (participates in β ladder)trans-123.3-36.6-170.3-170.656.6000113.9T255 N256 Q282 H284 V438 R480T255-H440 PolarHBondContact OG1-ND1 2.76Å; N256-H440 PolarHBondContact ND2-O 2.85Å; Q282-H440 PolarHBondContact O-N 2.78Å; Q282-H440 PolarHBondContact OE1-CD2 2.92Å; H284-H440 HydrophobicContact CB-CB 3.65Å; V438-H440 PolarHBondContact O-N 3.47Å; H440-R480 PolarHBondContact CD2-NH2 2.89Å; H440-R480 PolarHBondContact NE2-NH2 3.18Å
441Y98Very high98.4Very high2 Ų214.3 Ų14.31%0.0087%0.073CC..EExtended strand (participates in β ladder)trans-148.4141.3-175.7-163.8-102.7000112.4L281 Q282 M443 E470 H476 R480 E488L281-Y441 CarbonylContact C-O 3.56Å; L281-Y441 WeakPolarHBondContact CA-O 3.46Å; Q282-Y441 PolarHBondContact N-O 2.93Å; Y441-M443 HydrophobicContact CD1-SD 3.68Å; Y441-E470 HydrophobicContact CD1-CG 4.49Å; Y441-E470 HydrophobicContact CD2-CG 3.78Å; Y441-E470 VanDerWaalsContact CD2-OE1 3.3Å; Y441-E470 WeakPolarHBondContact CD2-OE1 3.38Å; Y441-E470 WeakPolarHBondContact CD2-OE2 3.42Å; Y441-E470 HydrophobicContact CE1-CG 4.05Å; Y441-E470 HydrophobicContact CE2-CB 3.65Å; Y441-E470 HydrophobicContact CE2-CG 3.35Å; Y441-E470 WeakPolarHBondContact CE2-OE2 3.14Å; Y441-E470 HydrophobicContact CG-CG 4.4Å; Y441-E470 VanDerWaalsContact CZ-CG 3.48Å; Y441-E470 WeakPolarHBondContact OH-CA 3.34Å; Y441-E470 WeakPolarHBondContact OH-CB 3.19Å; Y441-H476 AromaticContact CE1-CD2 3.55Å; Y441-R480 HydrophobicContact CD1-CB 4.43Å; Y441-E488 PolarHBondContact OH-OE2 2.81Å
442S98Very high98.4Very high0 Ų013.9 Ų13.90%07%0.072CC..EExtended strand (participates in β ladder)trans-82.3112169.1-70.20000110.1Y232 S233 E470Y232-S442 VanDerWaalsContact CD1-OG 3.31Å; Y232-S442 WeakPolarHBondContact CD1-OG 3.47Å; Y232-S442 WeakPolarHBondContact CE1-OG 3.39Å; Y232-S442 PolarHBondContact N-OG 2.88Å; S233-S442 PolarHBondContact N-OG 2.67Å; S233-S442 PolarHBondContact OG-N 3.2Å; S233-S442 PolarHBondContact OG-OG 3.38Å; S442-E470 PolarHBondContact N-OE1 3.31Å
443M98.1Very high98.4Very high2 Ų217.4 Ų17.41%0.019%0.085CC..  trans-81.2-33.5-178.2-54.6-59.2-59.100111.9R280 Q282 Y441 H476 G477 R480R280-M443 HydrophobicContact CB-CB 3.6Å; R280-M443 HydrophobicContact CB-CG 4.02Å; R280-M443 VanDerWaalsContact O-CB 3.24Å; R280-M443 WeakPolarHBondContact O-CB 3.43Å; R280-M443 PolarHBondContact O-N 3.36Å; Q282-M443 HydrophobicContact CB-CG 4.36Å; Q282-M443 HydrophobicContact CB-SD 3.79Å; Y441-M443 HydrophobicContact CD1-SD 3.68Å; M443-H476 HydrophobicContact CE-CB 3.21Å; M443-H476 HydrophobicContact SD-CB 4.47Å; M443-G477 WeakPolarHBondContact CB-O 3.28Å; M443-G477 VanDerWaalsContact CE-O 3.26Å; M443-G477 WeakPolarHBondContact CE-O 3.32Å; M443-R480 HydrophobicContact CE-CB 3.93Å; M443-R480 HydrophobicContact SD-CB 3.81Å
444G97.9Very high98.4Very high0 Ų017.3 Ų17.30%08%0.084CC..  trans-88.6162173.700000114.1Y232 I276 D277Y232-G444 WeakPolarHBondContact CE1-O 3.36Å; I276-G444 CarbonylContact O-C 3.57Å; I276-G444 WeakPolarHBondContact O-CA 3.45Å; D277-G444 VanDerWaalsContact C-CA 3.48Å; D277-G444 VanDerWaalsContact O-CA 3.25Å; D277-G444 WeakPolarHBondContact O-CA 3.48Å; D277-G444 PolarHBondContact O-N 3Å
445G98.6Very high98.4Very high0 Ų015.3 Ų15.30%08%0.078CC..EExtended strand (participates in β ladder)trans168.5-155.3-178.900000111.9L275 I276 M278 V471L275-G445 VanDerWaalsContact CA-O 3.31Å; L275-G445 WeakPolarHBondContact CA-O 3.44Å; I276-G445 PolarHBondContact N-O 3.21Å; I276-G445 PolarHBondContact O-N 3.45Å; M278-G445 PolarHBondContact SD-N 2.96Å; G445-V471 WeakPolarHBondContact CA-O 3.43Å
446I98.9Very high98.3Very high0 Ų016.7 Ų16.70%09%0.086CC..EExtended strand (participates in β ladder)trans-69.9131.8-178.6-56.7166.7000110.3L227 I265 A268 A273 L275 V454 A467 V471 T472 G473L227-I446 HydrophobicContact CD1-CD1 3.83Å; I265-I446 HydrophobicContact CG1-CG1 4.23Å; A268-I446 HydrophobicContact CB-CD1 3.38Å; A268-I446 HydrophobicContact CB-CG1 3.75Å; A273-I446 HydrophobicContact CB-CG2 4.27Å; L275-I446 HydrophobicContact CD2-CG1 4.2Å; I446-V454 HydrophobicContact CG2-CB 4.2Å; I446-V454 HydrophobicContact CG2-CG1 3.54Å; I446-V454 HydrophobicContact CG2-CG2 3.69Å; I446-A467 HydrophobicContact CB-CB 4.34Å; I446-A467 HydrophobicContact CD1-CB 4.06Å; I446-A467 HydrophobicContact CG2-CB 4.26Å; I446-V471 HydrophobicContact CD1-CG1 4.43Å; I446-V471 HydrophobicContact CD1-CG2 3.78Å; I446-V471 PolarHBondContact N-O 2.8Å; I446-T472 CarbonylContact O-C 3.55Å; I446-T472 VanDerWaalsContact O-CA 3.28Å; I446-T472 WeakPolarHBondContact O-CA 3.46Å; I446-T472 WeakPolarHBondContact O-CB 3.38Å; I446-G473 PolarHBondContact O-N 3.44Å
447V98.8Very high98.1Very high26 Ų2623.3 Ų23.316%0.15811%0.114CC..  trans-75.5128172.5178.10000110K274 I276 I455K274-V447 HydrophobicContact CB-CB 4.19Å; K274-V447 HydrophobicContact CB-CG2 4.13Å; K274-V447 HydrophobicContact CD-CG2 4.22Å; K274-V447 HydrophobicContact CG-CB 4.45Å; K274-V447 HydrophobicContact CG-CG2 3.91Å; K274-V447 WeakPolarHBondContact O-CG2 3.46Å; K274-V447 PolarHBondContact O-N 3.33Å; I276-V447 HydrophobicContact CB-CG2 3.68Å; I276-V447 HydrophobicContact CG2-CG2 3.68Å; V447-I455 HydrophobicContact CG1-CB 4.11Å; V447-I455 HydrophobicContact CG1-CG1 4.35Å; V447-I455 PolarHBondContact O-N 3.3Å
448T98.8Very high98Very high6 Ų628.5 Ų28.54%0.03714%0.142CC..BIsolated β-bridgetrans-123.2158.617267.30000111.5R453 V454 A467 T472T448-R453 WeakPolarHBondContact CA-O 3.11Å; T448-R453 WeakPolarHBondContact CB-O 3.46Å; T448-V454 HydrophobicContact CG2-CG2 4.45Å; T448-A467 HydrophobicContact CG2-CB 3.92Å; T448-T472 HydrophobicContact CG2-CG2 3.86Å
449D98.3Very high97.9Very high31 Ų3131.1 Ų31.117%0.16617%0.169CC..  trans-80.7-174.8162.569.39.6000111.7N451 M452 R453 I455D449-N451 PolarHBondContact O-N 3.39Å; D449-N451 VanDerWaalsContact OD1-C 3.31Å; D449-N451 VanDerWaalsContact OD1-CA 3.29Å; D449-N451 WeakPolarHBondContact OD1-CA 3.35Å; D449-N451 WeakPolarHBondContact OD1-CB 3.44Å; D449-N451 PolarHBondContact OD1-N 3.47Å; D449-M452 WeakPolarHBondContact O-CE 3.36Å; D449-M452 PolarHBondContact O-N 3.34Å; D449-M452 VanDerWaalsContact O-N 3.1Å; D449-M452 PolarHBondContact OD1-N 3.29Å; D449-M452 VanDerWaalsContact OD1-N 3.1Å; D449-R453 PolarHBondContact N-O 3.38Å; D449-R453 VanDerWaalsContact N-O 3.13Å; D449-R453 PolarHBondContact OD1-N 3.3Å; D449-R453 IonicContact OD1-NE 3.77Å; D449-R453 IonicContact OD2-CZ 3.1Å; D449-R453 IonicContact OD2-NE 2.73Å; D449-R453 PolarHBondContact OD2-NE 2.74Å; D449-R453 IonicContact OD2-NH2 2.66Å; D449-R453 PolarHBondContact OD2-NH2 3.24Å; D449-I455 HydrophobicContact CB-CD1 4.19Å
450T97.9Very high97.8Very high55 Ų5534.2 Ų34.234%0.33719%0.191SC..THydrogen-bonded Turntrans-71-6.9177.952.80000114.1L110 L111 L114 L495L110-T450 HydrophobicContact CB-CG2 3.72Å; L110-T450 HydrophobicContact CD1-CG2 4.44Å; L111-T450 HydrophobicContact CD2-CG2 4.37Å; L114-T450 WeakPolarHBondContact CD2-O 3.12Å; T450-L495 WeakPolarHBondContact O-CD2 3.26Å
451N98Very high97.8Very high60 Ų6036 Ų3632%0.32120%0.203SC..THydrogen-bonded Turntrans-1008.5172.5-68.9-37.7000112D449 R453 N499D449-N451 PolarHBondContact O-N 3.39Å; D449-N451 VanDerWaalsContact OD1-C 3.31Å; D449-N451 VanDerWaalsContact OD1-CA 3.29Å; D449-N451 WeakPolarHBondContact OD1-CA 3.35Å; D449-N451 WeakPolarHBondContact OD1-CB 3.44Å; D449-N451 PolarHBondContact OD1-N 3.47Å; N451-R453 HydrophobicContact CB-CG 4.31Å; N451-R453 PolarHBondContact O-N 2.62Å; N451-N499 WeakPolarHBondContact CA-ND2 3.35Å; N451-N499 WeakPolarHBondContact CB-ND2 3.31Å; N451-N499 PolarHBondContact O-ND2 2.86Å
452M98.7Very high97.8Very high6 Ų636.7 Ų36.73%0.0321%0.207CC..  trans64.917.5-178.6-50.2-63.4105.700114.2L111 L114 D449 Y466 A467 S492 L495 A496L111-M452 HydrophobicContact CD2-CE 3.83Å; L114-M452 HydrophobicContact CD2-CE 3.86Å; D449-M452 WeakPolarHBondContact O-CE 3.36Å; D449-M452 PolarHBondContact O-N 3.34Å; D449-M452 VanDerWaalsContact O-N 3.1Å; D449-M452 PolarHBondContact OD1-N 3.29Å; D449-M452 VanDerWaalsContact OD1-N 3.1Å; M452-Y466 WeakPolarHBondContact O-CA 3.37Å; M452-Y466 WeakPolarHBondContact O-CB 3.34Å; M452-A467 PolarHBondContact O-N 2.93Å; M452-A467 VanDerWaalsContact O-N 3.07Å; M452-S492 WeakPolarHBondContact SD-CB 3.49Å; M452-L495 HydrophobicContact CE-CD2 4.38Å; M452-L495 HydrophobicContact CG-CB 4.14Å; M452-L495 HydrophobicContact CG-CD2 4.25Å; M452-L495 HydrophobicContact CG-CG 4.22Å; M452-A496 HydrophobicContact CB-CB 3.63Å; M452-A496 HydrophobicContact CG-CB 4.02Å
453R98.6Very high97.8Very high78 Ų7841.8 Ų41.829%0.29423%0.229SC..EExtended strand (participates in β ladder)trans-76.5134.7173.9-64.4175.6-60.8-173.42.1109.2T448 D449 N451 V461 Y466T448-R453 WeakPolarHBondContact CA-O 3.11Å; T448-R453 WeakPolarHBondContact CB-O 3.46Å; D449-R453 PolarHBondContact N-O 3.38Å; D449-R453 VanDerWaalsContact N-O 3.13Å; D449-R453 PolarHBondContact OD1-N 3.3Å; D449-R453 IonicContact OD1-NE 3.77Å; D449-R453 IonicContact OD2-CZ 3.1Å; D449-R453 IonicContact OD2-NE 2.73Å; D449-R453 PolarHBondContact OD2-NE 2.74Å; D449-R453 IonicContact OD2-NH2 2.66Å; D449-R453 PolarHBondContact OD2-NH2 3.24Å; N451-R453 HydrophobicContact CB-CG 4.31Å; N451-R453 PolarHBondContact O-N 2.62Å; R453-V461 HydrophobicContact CB-CG1 3.94Å; R453-V461 HydrophobicContact CB-CG2 4.18Å; R453-V461 HydrophobicContact CG-CG1 4.43Å; R453-Y466 HydrophobicContact CB-CE1 4.44Å; R453-Y466 HydrophobicContact CG-CD1 3.9Å; R453-Y466 HydrophobicContact CG-CE1 3.4Å; R453-Y466 VanDerWaalsContact CG-CE1 3.4Å
454V98.8Very high97.7Very high0 Ų042.1 Ų42.10%023%0.233CC..EExtended strand (participates in β ladder)trans-72.6133.1-179.6173.90000110.6A273 I446 T448 V461 I462 L465 A467A273-V454 HydrophobicContact CB-CG1 3.51Å; I446-V454 HydrophobicContact CG2-CB 4.2Å; I446-V454 HydrophobicContact CG2-CG1 3.54Å; I446-V454 HydrophobicContact CG2-CG2 3.69Å; T448-V454 HydrophobicContact CG2-CG2 4.45Å; V454-V461 WeakPolarHBondContact O-CA 3.38Å; V454-I462 HydrophobicContact CG1-CD1 3.97Å; V454-I462 HydrophobicContact CG1-CG1 4.46Å; V454-I462 PolarHBondContact O-N 3.32Å; V454-L465 HydrophobicContact CB-CB 4.28Å; V454-L465 HydrophobicContact CB-CD2 3.94Å; V454-L465 HydrophobicContact CB-CG 3.93Å; V454-L465 HydrophobicContact CG1-CD2 3.91Å; V454-L465 HydrophobicContact CG1-CG 4.45Å; V454-L465 HydrophobicContact CG2-CB 4.44Å; V454-L465 HydrophobicContact CG2-CD2 4.05Å; V454-L465 HydrophobicContact CG2-CG 3.74Å; V454-L465 PolarHBondContact N-O 2.94Å; V454-A467 HydrophobicContact CG2-CB 3.76Å
455I98.6Very high97.7Very high23 Ų2342.1 Ų42.112%0.11823%0.233CC..EExtended strand (participates in β ladder)trans-102.8131-179.6-52.4-56.2000109.5K274 V447 D449 S460 V461K274-I455 WeakPolarHBondContact CB-O 3.47Å; K274-I455 PolarHBondContact N-O 3.43Å; V447-I455 HydrophobicContact CG1-CB 4.11Å; V447-I455 HydrophobicContact CG1-CG1 4.35Å; V447-I455 PolarHBondContact O-N 3.3Å; D449-I455 HydrophobicContact CB-CD1 4.19Å; I455-S460 WeakPolarHBondContact CA-O 3.1Å; I455-V461 HydrophobicContact CD1-CG2 3.75Å
456N97.7Very high97.8Very high30 Ų3042.4 Ų42.416%0.1623%0.234CC..BIsolated β-bridgetrans-80.3173.4175.77118.2000112.3G272 N458 G459 S460 I462G272-N456 VanDerWaalsContact O-CA 3.22Å; G272-N456 WeakPolarHBondContact O-CA 3.44Å; G272-N456 VanDerWaalsContact O-CB 3.28Å; G272-N456 WeakPolarHBondContact O-CB 3.3Å; N456-N458 PolarHBondContact O-N 3.32Å; N456-N458 VanDerWaalsContact O-N 3.14Å; N456-N458 WeakPolarHBondContact OD1-CA 3.39Å; N456-N458 WeakPolarHBondContact OD1-CB 3.47Å; N456-N458 PolarHBondContact OD1-N 3.04Å; N456-G459 PolarHBondContact O-N 3.01Å; N456-G459 PolarHBondContact OD1-N 2.86Å; N456-G459 VanDerWaalsContact OD1-N 3.16Å; N456-S460 VanDerWaalsContact CG-O 3.3Å; N456-S460 PolarHBondContact N-O 3.33Å; N456-S460 PolarHBondContact OD1-N 2.68Å; N456-S460 PolarHBondContact OD1-O 2.98Å; N456-I462 HydrophobicContact CB-CD1 3.99Å; N456-I462 HydrophobicContact CB-CG1 3.8Å
457F94Very high97.8Very high141 Ų14142.4 Ų42.462%0.61823%0.234SC*.THydrogen-bonded Turntrans-59.6-23.7179.864.7-89000114.1G272 G459G272-F457 WeakPolarHBondContact O-CD1 3.42Å; G272-F457 PolarHBondContact O-N 3.18Å; F457-G459 VanDerWaalsContact C-N 3.31Å
458N95.3Very high97.8Very high111 Ų11141.2 Ų41.259%0.59423%0.227SC*.THydrogen-bonded Turntrans-84.61175.8-65.3-33000113.6N456 S460N456-N458 PolarHBondContact O-N 3.32Å; N456-N458 VanDerWaalsContact O-N 3.14Å; N456-N458 WeakPolarHBondContact OD1-CA 3.39Å; N456-N458 WeakPolarHBondContact OD1-CB 3.47Å; N456-N458 PolarHBondContact OD1-N 3.04Å; N458-S460 VanDerWaalsContact C-N 3.33Å
459G96.4Very high97.8Very high55 Ų5540.9 Ų40.957%0.56723%0.225SC*.SBendtrans80.39.4-179.200000114.9N456 F457N456-G459 PolarHBondContact O-N 3.01Å; N456-G459 PolarHBondContact OD1-N 2.86Å; N456-G459 VanDerWaalsContact OD1-N 3.16Å; F457-G459 VanDerWaalsContact C-N 3.31Å
460S97.5Very high97.8Very high68 Ų6840.4 Ų40.448%0.47622%0.222SC..  trans-96.9153.5176.6-61.70000111.8I455 N456 N458I455-S460 WeakPolarHBondContact CA-O 3.1Å; N456-S460 VanDerWaalsContact CG-O 3.3Å; N456-S460 PolarHBondContact N-O 3.33Å; N456-S460 PolarHBondContact OD1-N 2.68Å; N456-S460 PolarHBondContact OD1-O 2.98Å; N458-S460 VanDerWaalsContact C-N 3.33Å
461V98.1Very high97.8Very high62 Ų6237.8 Ų37.838%0.37621%0.205SC..EExtended strand (participates in β ladder)trans-68.1133.1173.71700000110.4R453 V454 I455 K463R453-V461 HydrophobicContact CB-CG1 3.94Å; R453-V461 HydrophobicContact CB-CG2 4.18Å; R453-V461 HydrophobicContact CG-CG1 4.43Å; V454-V461 WeakPolarHBondContact O-CA 3.38Å; I455-V461 HydrophobicContact CD1-CG2 3.75Å; V461-K463 PolarHBondContact O-N 3.46Å
462I97.5Very high97.9Very high17 Ų1735.2 Ų35.29%0.08719%0.192CC..EExtended strand (participates in β ladder)trans-80.9105.9164-56.2-177.6000107.5V204 V271 A273 V454 N456 G464 L465V204-I462 HydrophobicContact CG2-CG2 4.07Å; V271-I462 HydrophobicContact CG2-CD1 4.3Å; A273-I462 HydrophobicContact CB-CD1 4.09Å; V454-I462 HydrophobicContact CG1-CD1 3.97Å; V454-I462 HydrophobicContact CG1-CG1 4.46Å; V454-I462 PolarHBondContact O-N 3.32Å; N456-I462 HydrophobicContact CB-CD1 3.99Å; N456-I462 HydrophobicContact CB-CG1 3.8Å; I462-G464 PolarHBondContact O-N 3.38Å; I462-L465 HydrophobicContact CB-CB 4.19Å; I462-L465 HydrophobicContact CB-CD2 4.46Å; I462-L465 HydrophobicContact CD1-CD2 4.3Å; I462-L465 HydrophobicContact CG2-CB 3.88Å; I462-L465 HydrophobicContact CG2-CD2 4.14Å; I462-L465 PolarHBondContact O-N 2.97Å
463K96.8Very high97.8Very high107 Ų10735.1 Ų35.147%0.46519%0.193SC..EExtended strand (participates in β ladder)trans-58.1138.4-179.8-173.6-176.9177.8-172.20110.4E202 G203 V204 V461 L465E202-K463 HydrophobicContact CB-CD 4.35Å; E202-K463 VanDerWaalsContact O-CB 3.28Å; E202-K463 WeakPolarHBondContact O-CB 3.31Å; E202-K463 WeakPolarHBondContact O-CD 3.29Å; E202-K463 IonicContact OE2-NZ 2.68Å; E202-K463 PolarHBondContact OE2-NZ 3.06Å; G203-K463 WeakPolarHBondContact CA-O 3.33Å; V204-K463 PolarHBondContact N-O 3.34Å; V461-K463 PolarHBondContact O-N 3.46Å; K463-L465 VanDerWaalsContact C-N 3.26Å; K463-L465 PolarHBondContact O-N 3.43Å
464G97Very high97.8Very high8 Ų831.6 Ų31.68%0.08218%0.18CC..EExtended strand (participates in β ladder)trans77.12.418000000114.8A224 V225 I462A224-G464 CarbonylContact C-O 3.59Å; A224-G464 WeakPolarHBondContact CA-O 3.46Å; V225-G464 PolarHBondContact N-O 3.13Å; I462-G464 PolarHBondContact O-N 3.38Å
465L98.6Very high97.7Very high1 Ų132.1 Ų32.11%0.00518%0.184CC..EExtended strand (participates in β ladder)trans-121123.9-178.9-170.263.6000112.8L197 V204 V225 L227 V271 V454 I462 K463L197-L465 HydrophobicContact CD1-CD1 3.93Å; L197-L465 HydrophobicContact CD1-CD2 3.98Å; L197-L465 HydrophobicContact CD2-CD1 3.99Å; V204-L465 HydrophobicContact CB-CB 4.18Å; V204-L465 HydrophobicContact CG1-CD1 4.44Å; V204-L465 HydrophobicContact CG2-CB 3.88Å; V204-L465 HydrophobicContact CG2-CD1 4.31Å; V204-L465 HydrophobicContact CG2-CD2 4.19Å; V204-L465 HydrophobicContact CG2-CG 4.34Å; V225-L465 HydrophobicContact CB-CD1 4.25Å; V225-L465 HydrophobicContact CG1-CD1 4.38Å; L227-L465 HydrophobicContact CD1-CD1 4.03Å; L227-L465 HydrophobicContact CG-CD1 4.11Å; V271-L465 HydrophobicContact CG2-CD2 3.9Å; V454-L465 HydrophobicContact CB-CB 4.28Å; V454-L465 HydrophobicContact CB-CD2 3.94Å; V454-L465 HydrophobicContact CB-CG 3.93Å; V454-L465 HydrophobicContact CG1-CD2 3.91Å; V454-L465 HydrophobicContact CG1-CG 4.45Å; V454-L465 HydrophobicContact CG2-CB 4.44Å; V454-L465 HydrophobicContact CG2-CD2 4.05Å; V454-L465 HydrophobicContact CG2-CG 3.74Å; V454-L465 PolarHBondContact N-O 2.94Å; I462-L465 HydrophobicContact CB-CB 4.19Å; I462-L465 HydrophobicContact CB-CD2 4.46Å; I462-L465 HydrophobicContact CD1-CD2 4.3Å; I462-L465 HydrophobicContact CG2-CB 3.88Å; I462-L465 HydrophobicContact CG2-CD2 4.14Å; I462-L465 PolarHBondContact O-N 2.97Å; K463-L465 VanDerWaalsContact C-N 3.26Å; K463-L465 PolarHBondContact O-N 3.43Å
466Y98.9Very high97.7Very high6 Ų631.2 Ų31.22%0.02418%0.179CC..EExtended strand (participates in β ladder)trans-125.8159.5177.5-57.9-104.1000109.8A224 V225 V226 L227 M452 R453 N499 A500 D503A224-Y466 HydrophobicContact CB-CD2 4.34Å; A224-Y466 HydrophobicContact CB-CE2 4.05Å; V225-Y466 PolarHBondContact O-N 2.84Å; V226-Y466 WeakPolarHBondContact CA-O 3.18Å; L227-Y466 PolarHBondContact N-O 3.18Å; M452-Y466 WeakPolarHBondContact O-CA 3.37Å; M452-Y466 WeakPolarHBondContact O-CB 3.34Å; R453-Y466 HydrophobicContact CB-CE1 4.44Å; R453-Y466 HydrophobicContact CG-CD1 3.9Å; R453-Y466 HydrophobicContact CG-CE1 3.4Å; R453-Y466 VanDerWaalsContact CG-CE1 3.4Å; Y466-N499 HydrophobicContact CD1-CB 4.32Å; Y466-N499 HydrophobicContact CE1-CB 3.75Å; Y466-A500 HydrophobicContact CD2-CB 3.73Å; Y466-A500 HydrophobicContact CE2-CB 3.88Å; Y466-A500 HydrophobicContact CG-CB 4.14Å; Y466-D503 VanDerWaalsContact OH-CB 3.25Å; Y466-D503 WeakPolarHBondContact OH-CB 3.44Å; Y466-D503 VanDerWaalsContact OH-CG 3.29Å; Y466-D503 PolarHBondContact OH-OD2 2.88Å
467A98.9Very high97.6Very high0 Ų029.8 Ų29.80%017%0.171CC..EExtended strand (participates in β ladder)trans-146.5144.6175.700000111.3L227 I446 T448 M452 V454 V471 T472L227-A467 HydrophobicContact CB-CB 4.34Å; L227-A467 CarbonylContact O-C 3.6Å; L227-A467 VanDerWaalsContact O-CA 3.29Å; L227-A467 WeakPolarHBondContact O-CA 3.21Å; I446-A467 HydrophobicContact CB-CB 4.34Å; I446-A467 HydrophobicContact CD1-CB 4.06Å; I446-A467 HydrophobicContact CG2-CB 4.26Å; T448-A467 HydrophobicContact CG2-CB 3.92Å; M452-A467 PolarHBondContact O-N 2.93Å; M452-A467 VanDerWaalsContact O-N 3.07Å; V454-A467 HydrophobicContact CG2-CB 3.76Å; A467-V471 HydrophobicContact CB-CG1 4.05Å; A467-T472 HydrophobicContact CB-CG2 3.69Å
468A98.9Very high97.7Very high0 Ų026.5 Ų26.50%016%0.155CC..  trans-150.5155-17900000113.4L227 T228 V471 A496L227-A468 PolarHBondContact O-N 3.48Å; T228-A468 HydrophobicContact CG2-CB 3.96Å; A468-V471 WeakPolarHBondContact O-CG1 3.46Å; A468-A496 HydrophobicContact CB-CB 3.89Å
469G98.6Very high97.8Very high0 Ų021.5 Ų21.50%013%0.128CC..G310 helixtrans69.2-155.5-174.600000113V471 T472 S492G469-V471 PolarHBondContact O-N 3.47Å; G469-T472 PolarHBondContact O-N 3.34Å; G469-T472 PolarHBondContact O-OG1 3Å; G469-S492 PolarHBondContact N-OG 3.11Å
470E98.7Very high97.9Very high21 Ų2119.3 Ų19.310%0.09810%0.103CC..G310 helixtrans-64-6.7-170.2-174.1173.5173.600115.7Y441 S442Y441-E470 HydrophobicContact CD1-CG 4.49Å; Y441-E470 HydrophobicContact CD2-CG 3.78Å; Y441-E470 VanDerWaalsContact CD2-OE1 3.3Å; Y441-E470 WeakPolarHBondContact CD2-OE1 3.38Å; Y441-E470 WeakPolarHBondContact CD2-OE2 3.42Å; Y441-E470 HydrophobicContact CE1-CG 4.05Å; Y441-E470 HydrophobicContact CE2-CB 3.65Å; Y441-E470 HydrophobicContact CE2-CG 3.35Å; Y441-E470 WeakPolarHBondContact CE2-OE2 3.14Å; Y441-E470 HydrophobicContact CG-CG 4.4Å; Y441-E470 VanDerWaalsContact CZ-CG 3.48Å; Y441-E470 WeakPolarHBondContact OH-CA 3.34Å; Y441-E470 WeakPolarHBondContact OH-CB 3.19Å; S442-E470 PolarHBondContact N-OE1 3.31Å
471V98.8Very high97.8Very high0 Ų016.3 Ų16.30%08%0.082CC..G310 helixtrans-74.4-18.4171.376.90000112L227 T229 I265 G445 I446 A467 A468 G469L227-V471 HydrophobicContact CB-CG1 4.42Å; L227-V471 VanDerWaalsContact O-CG1 3.27Å; L227-V471 WeakPolarHBondContact O-CG1 3.24Å; T229-V471 VanDerWaalsContact OG1-CG2 3.3Å; T229-V471 WeakPolarHBondContact OG1-CG2 3.47Å; I265-V471 HydrophobicContact CG1-CG2 3.83Å; G445-V471 WeakPolarHBondContact CA-O 3.43Å; I446-V471 HydrophobicContact CD1-CG1 4.43Å; I446-V471 HydrophobicContact CD1-CG2 3.78Å; I446-V471 PolarHBondContact N-O 2.8Å; A467-V471 HydrophobicContact CB-CG1 4.05Å; A468-V471 WeakPolarHBondContact O-CG1 3.46Å; G469-V471 PolarHBondContact O-N 3.47Å
472T98.8Very high97.8Very high6 Ų613.4 Ų13.44%0.0376%0.064CC..BIsolated β-bridgetrans-89.6160.9178.370.40000111.6I446 T448 A467 G469I446-T472 CarbonylContact O-C 3.55Å; I446-T472 VanDerWaalsContact O-CA 3.28Å; I446-T472 WeakPolarHBondContact O-CA 3.46Å; I446-T472 WeakPolarHBondContact O-CB 3.38Å; T448-T472 HydrophobicContact CG2-CG2 3.86Å; A467-T472 HydrophobicContact CB-CG2 3.69Å; G469-T472 PolarHBondContact O-N 3.34Å; G469-T472 PolarHBondContact O-OG1 3Å
473G98.2Very high97.7Very high4 Ų412.8 Ų12.84%0.0416%0.062CC..  trans-119.4164.7173.200000112.4I446I446-G473 PolarHBondContact O-N 3.44Å
474G97.5Very high97.8Very high4 Ų47.7 Ų7.74%0.0414%0.04CC..SBendtrans95.3-21.1170.500000115.9N107 N108 H476N107-G474 CarbonylContact C-O 3.54Å; N107-G474 WeakPolarHBondContact CA-O 3.35Å; N108-G474 PolarHBondContact N-O 3.09Å; G474-H476 VanDerWaalsContact C-N 3.31Å; G474-H476 PolarHBondContact O-N 2.67Å
475T97.9Very high97.8Very high11 Ų118.3 Ų8.37%0.0674%0.043CC..SBendtrans-61-41.5175.5-51.80000111.7N107 V112 L115 E488N107-T475 PolarHBondContact ND2-O 3.36Å; V112-T475 WeakPolarHBondContact CG2-O 3.35Å; L115-T475 HydrophobicContact CD1-CG2 3.81Å; T475-E488 WeakPolarHBondContact CB-OE1 3.16Å; T475-E488 PolarHBondContact OG1-OE1 3.13Å
476H97.8Very high97.8Very high4 Ų48.4 Ų8.42%0.0194%0.043CC..SBendtrans-108.1-15.3-169.3-53.9-61.3000114.8G103 N107 Y441 M443 G474 Y478 R480 E488G103-H476 WeakPolarHBondContact CA-O 3.11Å; N107-H476 WeakPolarHBondContact ND2-CA 3.37Å; N107-H476 PolarHBondContact ND2-O 2.95Å; Y441-H476 AromaticContact CE1-CD2 3.55Å; M443-H476 HydrophobicContact CE-CB 3.21Å; M443-H476 HydrophobicContact SD-CB 4.47Å; G474-H476 VanDerWaalsContact C-N 3.31Å; G474-H476 PolarHBondContact O-N 2.67Å; H476-Y478 PolarHBondContact O-N 2.89Å; H476-R480 HydrophobicContact CB-CB 4.11Å; H476-R480 HydrophobicContact CB-CG 4.18Å; H476-E488 IonicContact CD2-OE1 2.69Å; H476-E488 IonicContact CD2-OE2 3.28Å; H476-E488 IonicContact CE1-OE2 2.98Å; H476-E488 IonicContact NE2-OE1 3.17Å; H476-E488 PolarHBondContact NE2-OE1 3.36Å; H476-E488 IonicContact NE2-OE2 3.31Å; H476-E488 PolarHBondContact NE2-OE2 3.13Å
477G96Very high97.8Very high0 Ų08.1 Ų8.10%04%0.042CC..THydrogen-bonded Turntrans66.5-127.4176.900000113M443M443-G477 WeakPolarHBondContact CB-O 3.28Å; M443-G477 VanDerWaalsContact CE-O 3.26Å; M443-G477 WeakPolarHBondContact CE-O 3.32Å
478Y96.6Very high97.8Very high71 Ų718.4 Ų8.428%0.2784%0.043SC..THydrogen-bonded Turntrans-68.3-45.7-175-172.8-88.6000113.8G103 Q104 M106 D329 H476G103-Y478 WeakPolarHBondContact O-CB 3.5Å; G103-Y478 PolarHBondContact O-N 3.43Å; Q104-Y478 HydrophobicContact CB-CG 4.23Å; Q104-Y478 VanDerWaalsContact CD-CD1 3.45Å; Q104-Y478 VanDerWaalsContact CD-CG 3.49Å; Q104-Y478 HydrophobicContact CG-CD1 3.87Å; Q104-Y478 HydrophobicContact CG-CG 3.84Å; M106-Y478 HydrophobicContact SD-CD2 3.99Å; M106-Y478 HydrophobicContact SD-CG 4.44Å; D329-Y478 HydrophobicContact CB-CE1 4.08Å; D329-Y478 WeakPolarHBondContact OD2-CE1 3.25Å; H476-Y478 PolarHBondContact O-N 2.89Å
479D96.8Very high97.8Very high6 Ų68.9 Ų8.93%0.0325%0.047CC..SBendtrans-145153.4-177.5-16530.8000111.8A102 G103 Q282 R328 D329A102-D479 CarbonylContact C-O 3.59Å; A102-D479 WeakPolarHBondContact O-CB 3.48Å; G103-D479 WeakPolarHBondContact CA-O 3.44Å; G103-D479 PolarHBondContact N-O 3.42Å; Q282-D479 WeakPolarHBondContact CB-OD1 3.34Å; Q282-D479 VanDerWaalsContact CD-OD1 3.27Å; Q282-D479 WeakPolarHBondContact CG-OD1 3.49Å; Q282-D479 PolarHBondContact NE2-OD1 2.91Å; R328-D479 WeakPolarHBondContact CB-OD2 3.48Å; D329-D479 PolarHBondContact N-OD2 2.95Å
480R97.5Very high97.8Very high10 Ų108.9 Ų8.94%0.0385%0.047CC..PPolyproline II helixtrans-103.9117.7-171.9-172.6-163.873.7-170.6-3.1113.1Q282 R328 H440 Y441 M443 H476 G482 N484 S485Q282-R480 PolarHBondContact NE2-O 3.43Å; R328-R480 PolarHBondContact NH1-O 3.48Å; H440-R480 PolarHBondContact CD2-NH2 2.89Å; H440-R480 PolarHBondContact NE2-NH2 3.18Å; Y441-R480 HydrophobicContact CD1-CB 4.43Å; M443-R480 HydrophobicContact CE-CB 3.93Å; M443-R480 HydrophobicContact SD-CB 3.81Å; H476-R480 HydrophobicContact CB-CB 4.11Å; H476-R480 HydrophobicContact CB-CG 4.18Å; R480-G482 PolarHBondContact O-N 3.32Å; R480-N484 HydrophobicContact CG-CB 4.34Å; R480-S485 PolarHBondContact NH1-OG 3.4Å
481L96.5Very high97.7Very high5 Ų58.1 Ų8.13%0.0264%0.044CC..PPolyproline II helixtrans-55.3133.8170.8-166.468.8000111.9F95 D98 A102 H142 G483 N484F95-L481 HydrophobicContact CD2-CD2 4.38Å; F95-L481 HydrophobicContact CE2-CD2 4.14Å; D98-L481 HydrophobicContact CB-CD2 3.83Å; A102-L481 HydrophobicContact CB-CB 4.04Å; A102-L481 HydrophobicContact CB-CD1 4.18Å; H142-L481 VanDerWaalsContact CE1-CD2 3.48Å; H142-L481 WeakPolarHBondContact CE1-CD2 3.21Å; H142-L481 VanDerWaalsContact CE1-CG 3.44Å; H142-L481 WeakPolarHBondContact CE1-CG 3.17Å; H142-L481 WeakPolarHBondContact NE2-CG 3.46Å; L481-G483 PolarHBondContact O-N 3.32Å; L481-N484 WeakPolarHBondContact O-CB 3.46Å; L481-N484 PolarHBondContact O-N 2.93Å
482G96.6Very high97.7Very high0 Ų08.5 Ų8.50%05%0.047CC..THydrogen-bonded Turntrans-59.2131.9-174.100000112.6N76 H142 R480 N484N76-G482 PolarHBondContact ND2-O 3.15Å; N76-G482 PolarHBondContact OD1-O 3.36Å; H142-G482 PolarHBondContact CE1-O 2.86Å; H142-G482 VanDerWaalsContact CE1-O 3.29Å; H142-G482 PolarHBondContact NE2-O 3.45Å; R480-G482 PolarHBondContact O-N 3.32Å; G482-N484 VanDerWaalsContact C-N 3.35Å; G482-N484 PolarHBondContact O-N 3.26Å
483G96.8Very high97.7Very high5 Ų58.2 Ų8.25%0.0525%0.045CC..THydrogen-bonded Turntrans87.8-11.4-179.400000115.7G74 N76 L481 S485G74-G483 WeakPolarHBondContact O-CA 3.48Å; N76-G483 VanDerWaalsContact ND2-C 3.27Å; L481-G483 PolarHBondContact O-N 3.32Å; G483-S485 VanDerWaalsContact C-N 3.33Å; G483-S485 PolarHBondContact O-N 2.96Å
484N98.3Very high97.8Very high0 Ų09.3 Ų9.30%05%0.052CC..Hα-helixtrans-66.1-30.8178.7-83.510.9000113.6N76 F95 T99 R480 L481 G482 L486 I487 E488N76-N484 PolarHBondContact ND2-N 3.32Å; N76-N484 PolarHBondContact ND2-OD1 3.35Å; F95-N484 WeakPolarHBondContact CE2-OD1 3.24Å; F95-N484 VanDerWaalsContact CZ-OD1 3.22Å; F95-N484 WeakPolarHBondContact CZ-OD1 3.34Å; T99-N484 WeakPolarHBondContact CG2-ND2 3.35Å; T99-N484 PolarHBondContact OG1-ND2 3.04Å; R480-N484 HydrophobicContact CG-CB 4.34Å; L481-N484 WeakPolarHBondContact O-CB 3.46Å; L481-N484 PolarHBondContact O-N 2.93Å; G482-N484 VanDerWaalsContact C-N 3.35Å; G482-N484 PolarHBondContact O-N 3.26Å; N484-L486 VanDerWaalsContact C-N 3.33Å; N484-L486 PolarHBondContact O-N 3.43Å; N484-I487 WeakPolarHBondContact O-CG2 3.39Å; N484-I487 PolarHBondContact O-N 3.05Å; N484-E488 WeakPolarHBondContact O-CB 3.42Å; N484-E488 PolarHBondContact O-N 3.2Å
485S97.8Very high97.8Very high20 Ų2010.1 Ų10.114%0.146%0.055CC..Hα-helixtrans-64.6-35.1-175.559.80000113.7R480 G483 C489R480-S485 PolarHBondContact NH1-OG 3.4Å; G483-S485 VanDerWaalsContact C-N 3.33Å; G483-S485 PolarHBondContact O-N 2.96Å; S485-C489 WeakPolarHBondContact O-CB 3.41Å; S485-C489 PolarHBondContact O-N 3.37Å; S485-C489 PolarHBondContact O-SG 3.14Å
486L98.3Very high97.8Very high3 Ų39.6 Ų9.62%0.0165%0.052CC..Hα-helixtrans-69-44.6178.9-71.8175000110.8L39 A71 G74 I75 I161 L165 N484 C489 I490L39-L486 HydrophobicContact CD2-CB 4.46Å; L39-L486 HydrophobicContact CD2-CD2 3.62Å; A71-L486 HydrophobicContact CB-CD1 4.01Å; A71-L486 HydrophobicContact CB-CD2 3.99Å; A71-L486 HydrophobicContact CB-CG 4.21Å; G74-L486 WeakPolarHBondContact O-CD1 3.43Å; I75-L486 HydrophobicContact CB-CB 4.17Å; I75-L486 HydrophobicContact CB-CD1 4.31Å; I75-L486 HydrophobicContact CD1-CB 4.23Å; I75-L486 HydrophobicContact CG1-CB 4Å; I161-L486 HydrophobicContact CG2-CD1 4.12Å; L165-L486 HydrophobicContact CD1-CB 4.25Å; L165-L486 HydrophobicContact CD1-CD1 3.76Å; L165-L486 HydrophobicContact CD1-CD2 4.03Å; L165-L486 HydrophobicContact CD1-CG 4.24Å; N484-L486 VanDerWaalsContact C-N 3.33Å; N484-L486 PolarHBondContact O-N 3.43Å; L486-C489 PolarHBondContact O-N 3.16Å; L486-I490 WeakPolarHBondContact O-CG1 3.28Å; L486-I490 PolarHBondContact O-N 3.4Å; L486-I490 VanDerWaalsContact O-N 3.11Å
487I98.5Very high97.9Very high0 Ų09.4 Ų9.40%05%0.051CC..Hα-helixtrans-72.1-33178.2-171.867.1000112.1I75 N76 L115 F122 N484 I490 S491I75-I487 HydrophobicContact CD1-CB 4.23Å; I75-I487 HydrophobicContact CD1-CD1 4.23Å; I75-I487 HydrophobicContact CG1-CB 3.93Å; N76-I487 HydrophobicContact CB-CG2 4.38Å; L115-I487 HydrophobicContact CD1-CG2 4.27Å; L115-I487 HydrophobicContact CD2-CG2 3.86Å; L115-I487 HydrophobicContact CG-CG2 4.08Å; F122-I487 HydrophobicContact CB-CD1 4.02Å; F122-I487 HydrophobicContact CD2-CD1 4.15Å; N484-I487 WeakPolarHBondContact O-CG2 3.39Å; N484-I487 PolarHBondContact O-N 3.05Å; I487-I490 PolarHBondContact O-N 3.22Å; I487-S491 WeakPolarHBondContact O-CB 3.29Å; I487-S491 PolarHBondContact O-N 3.28Å
488E98.5Very high97.9Very high6 Ų611.3 Ų11.33%0.0286%0.062CC..Hα-helixtrans-59.5-50.6169.4178.8-179.1-138.800110.9L115 Y441 T475 H476 N484 I490 S491 S492L115-E488 HydrophobicContact CD1-CB 3.77Å; L115-E488 HydrophobicContact CD1-CG 4.48Å; Y441-E488 PolarHBondContact OH-OE2 2.81Å; T475-E488 WeakPolarHBondContact CB-OE1 3.16Å; T475-E488 PolarHBondContact OG1-OE1 3.13Å; H476-E488 IonicContact CD2-OE1 2.69Å; H476-E488 IonicContact CD2-OE2 3.28Å; H476-E488 IonicContact CE1-OE2 2.98Å; H476-E488 IonicContact NE2-OE1 3.17Å; H476-E488 PolarHBondContact NE2-OE1 3.36Å; H476-E488 IonicContact NE2-OE2 3.31Å; H476-E488 PolarHBondContact NE2-OE2 3.13Å; N484-E488 WeakPolarHBondContact O-CB 3.42Å; N484-E488 PolarHBondContact O-N 3.2Å; E488-I490 VanDerWaalsContact C-N 3.3Å; E488-I490 PolarHBondContact O-N 3.05Å; E488-S491 PolarHBondContact O-N 3.4Å; E488-S492 VanDerWaalsContact O-CB 3.3Å; E488-S492 WeakPolarHBondContact O-CB 3.42Å; E488-S492 PolarHBondContact O-N 3.17Å; E488-S492 PolarHBondContact O-OG 3.34Å
489C98.7Very high98Very high11 Ų119.3 Ų9.37%0.0746%0.057CC..Hα-helixtrans-55.3-46.8179.1-74.70000111.4L39 A40 S485 L486 G493L39-C489 HydrophobicContact CB-CB 4.01Å; L39-C489 HydrophobicContact CD2-CB 4.06Å; L39-C489 HydrophobicContact CG-CB 3.97Å; A40-C489 WeakPolarHBondContact CA-O 3.34Å; A40-C489 HydrophobicContact CB-CB 3.96Å; S485-C489 WeakPolarHBondContact O-CB 3.41Å; S485-C489 PolarHBondContact O-N 3.37Å; S485-C489 PolarHBondContact O-SG 3.14Å; L486-C489 PolarHBondContact O-N 3.16Å; C489-G493 VanDerWaalsContact O-CA 3.31Å; C489-G493 WeakPolarHBondContact O-CA 3.34Å; C489-G493 PolarHBondContact O-N 2.95Å
490I98.7Very high98.1Very high0 Ų09 Ų90%06%0.055CC..Hα-helixtrans-66-50.6-179.8-67.6164.5000110.9L39 I75 F122 L165 Y169 L486 I487 E488 S494L39-I490 HydrophobicContact CD1-CG1 4.25Å; L39-I490 HydrophobicContact CD2-CD1 4.14Å; L39-I490 HydrophobicContact CD2-CG1 3.87Å; L39-I490 HydrophobicContact CG-CG1 4.02Å; I75-I490 HydrophobicContact CD1-CD1 3.51Å; F122-I490 HydrophobicContact CB-CG2 3.94Å; F122-I490 HydrophobicContact CD1-CG2 3.44Å; F122-I490 VanDerWaalsContact CD1-CG2 3.44Å; F122-I490 HydrophobicContact CD2-CG2 3.84Å; F122-I490 HydrophobicContact CE1-CG2 3.78Å; F122-I490 HydrophobicContact CE2-CG2 4.16Å; F122-I490 HydrophobicContact CG-CG2 3.46Å; F122-I490 VanDerWaalsContact CG-CG2 3.46Å; F122-I490 HydrophobicContact CZ-CG2 4.13Å; L165-I490 HydrophobicContact CD2-CD1 4.29Å; Y169-I490 HydrophobicContact CE1-CG2 4.29Å; Y169-I490 HydrophobicContact CE2-CD1 3.59Å; Y169-I490 HydrophobicContact CE2-CG1 3.79Å; Y169-I490 HydrophobicContact CE2-CG2 4.46Å; Y169-I490 WeakPolarHBondContact OH-CG2 3.33Å; L486-I490 WeakPolarHBondContact O-CG1 3.28Å; L486-I490 PolarHBondContact O-N 3.4Å; L486-I490 VanDerWaalsContact O-N 3.11Å; I487-I490 PolarHBondContact O-N 3.22Å; E488-I490 VanDerWaalsContact C-N 3.3Å; E488-I490 PolarHBondContact O-N 3.05Å; I490-S494 WeakPolarHBondContact O-CB 3.48Å; I490-S494 PolarHBondContact O-N 3.34Å
491S98.2Very high98Very high4 Ų49 Ų93%0.0286%0.057CC..Hα-helixtrans-67.2-52.1-173.9-174.30000112.2R118 I487 E488 L495R118-S491 VanDerWaalsContact CD-OG 3.26Å; R118-S491 WeakPolarHBondContact CD-OG 3.22Å; R118-S491 PolarHBondContact NE-OG 2.96Å; I487-S491 WeakPolarHBondContact O-CB 3.29Å; I487-S491 PolarHBondContact O-N 3.28Å; E488-S491 PolarHBondContact O-N 3.4Å; S491-L495 WeakPolarHBondContact O-CB 3.3Å; S491-L495 PolarHBondContact O-N 3.41Å
492S98.7Very high97.8Very high9 Ų911.4 Ų11.46%0.0638%0.078CC..Hα-helixtrans-68.2-42178.662.40000111.6M452 G469 E488 L495 A496M452-S492 WeakPolarHBondContact SD-CB 3.49Å; G469-S492 PolarHBondContact N-OG 3.11Å; E488-S492 VanDerWaalsContact O-CB 3.3Å; E488-S492 WeakPolarHBondContact O-CB 3.42Å; E488-S492 PolarHBondContact O-N 3.17Å; E488-S492 PolarHBondContact O-OG 3.34Å; S492-L495 PolarHBondContact O-N 2.96Å; S492-A496 VanDerWaalsContact O-CB 3.3Å; S492-A496 WeakPolarHBondContact O-CB 3.48Å; S492-A496 PolarHBondContact O-N 2.96Å
493G98.8Very high97.2Very high0 Ų014.9 Ų14.90%010%0.096CC..Hα-helixtrans-59.3-55178.500000111A40 A44 C489 L495 A496 G497A40-G493 WeakPolarHBondContact O-CA 3.4Å; A44-G493 WeakPolarHBondContact CA-O 3.4Å; A44-G493 WeakPolarHBondContact CB-O 3.43Å; A44-G493 PolarHBondContact N-O 2.82Å; C489-G493 VanDerWaalsContact O-CA 3.31Å; C489-G493 WeakPolarHBondContact O-CA 3.34Å; C489-G493 PolarHBondContact O-N 2.95Å; G493-L495 VanDerWaalsContact C-N 3.27Å; G493-L495 PolarHBondContact O-N 3.33Å; G493-A496 PolarHBondContact O-N 3.35Å; G493-G497 PolarHBondContact O-N 3.25Å
494S98.4Very high95.6Very high26 Ų2614.8 Ų14.818%0.18210%0.096CC..Hα-helixtrans-52.8-45.5176.9170.40000112.3I490 V498I490-S494 WeakPolarHBondContact O-CB 3.48Å; I490-S494 PolarHBondContact O-N 3.34Å; S494-V498 WeakPolarHBondContact O-CG2 3.16Å; S494-V498 PolarHBondContact O-N 2.73Å; S494-V498 VanDerWaalsContact O-N 3.09Å
495L98.2Very high93.5Very high22 Ų2217.4 Ų17.412%0.11512%0.123CC..Hα-helixtrans-70.5-42.5-177.8-172.959000112.8L114 T450 M452 S491 S492 G493 G497 V498 N499L114-L495 HydrophobicContact CD2-CD2 3.85Å; T450-L495 WeakPolarHBondContact O-CD2 3.26Å; M452-L495 HydrophobicContact CE-CD2 4.38Å; M452-L495 HydrophobicContact CG-CB 4.14Å; M452-L495 HydrophobicContact CG-CD2 4.25Å; M452-L495 HydrophobicContact CG-CG 4.22Å; S491-L495 WeakPolarHBondContact O-CB 3.3Å; S491-L495 PolarHBondContact O-N 3.41Å; S492-L495 PolarHBondContact O-N 2.96Å; G493-L495 VanDerWaalsContact C-N 3.27Å; G493-L495 PolarHBondContact O-N 3.33Å; L495-G497 VanDerWaalsContact C-N 3.32Å; L495-G497 PolarHBondContact O-N 2.87Å; L495-V498 PolarHBondContact O-N 2.86Å; L495-N499 WeakPolarHBondContact CD1-ND2 3.25Å; L495-N499 WeakPolarHBondContact O-CB 3.2Å; L495-N499 VanDerWaalsContact O-CG 3.32Å; L495-N499 PolarHBondContact O-N 3.24Å; L495-N499 PolarHBondContact O-ND2 3.21Å
496A98.8Very high91.3Very high0 Ų024.3 Ų24.30%015%0.15CC..Hα-helixtrans-61-42.8176.100000111.3V226 M452 A468 S492 G493 N499 A500V226-A496 HydrophobicContact CG1-CB 3.7Å; M452-A496 HydrophobicContact CB-CB 3.63Å; M452-A496 HydrophobicContact CG-CB 4.02Å; A468-A496 HydrophobicContact CB-CB 3.89Å; S492-A496 VanDerWaalsContact O-CB 3.3Å; S492-A496 WeakPolarHBondContact O-CB 3.48Å; S492-A496 PolarHBondContact O-N 2.96Å; G493-A496 PolarHBondContact O-N 3.35Å; A496-N499 PolarHBondContact O-N 2.63Å; A496-A500 WeakPolarHBondContact O-CB 3.22Å; A496-A500 PolarHBondContact O-N 2.77Å
497G98.5Very high88.8Confident0 Ų031.8 Ų31.80%018%0.182CC..Hα-helixtrans-60.7-49.4175.700000113.3A44 A48 G493 L495 N499 A501A44-G497 WeakPolarHBondContact O-CA 3.36Å; A48-G497 WeakPolarHBondContact CA-O 3.48Å; A48-G497 WeakPolarHBondContact CB-O 3.4Å; G493-G497 PolarHBondContact O-N 3.25Å; L495-G497 VanDerWaalsContact C-N 3.32Å; L495-G497 PolarHBondContact O-N 2.87Å; G497-N499 PolarHBondContact O-N 3.38Å; G497-A501 WeakPolarHBondContact O-CB 3.46Å; G497-A501 PolarHBondContact O-N 3.37Å; G497-A501 VanDerWaalsContact O-N 3.09Å
498V97.8Very high86.1Confident39 Ų3934.5 Ų34.524%0.23620%0.197CC..Hα-helixtrans-59.9-47.2178.1168.20000111.2Q51 S494 L495 A501 A502Q51-V498 HydrophobicContact CG-CB 4.49Å; Q51-V498 HydrophobicContact CG-CG1 4.25Å; Q51-V498 HydrophobicContact CG-CG2 4.44Å; S494-V498 WeakPolarHBondContact O-CG2 3.16Å; S494-V498 PolarHBondContact O-N 2.73Å; S494-V498 VanDerWaalsContact O-N 3.09Å; L495-V498 PolarHBondContact O-N 2.86Å; V498-A501 PolarHBondContact O-N 2.89Å; V498-A502 WeakPolarHBondContact O-CB 3.44Å; V498-A502 PolarHBondContact O-N 2.73Å
499N98.3Very high83.3Confident30 Ų3040.5 Ų40.516%0.1622%0.224CC..Hα-helixtrans-72.2-37.4-176.5-68.2-24.6000112.4N451 Y466 L495 A496 G497 A501 A502 D503N451-N499 WeakPolarHBondContact CA-ND2 3.35Å; N451-N499 WeakPolarHBondContact CB-ND2 3.31Å; N451-N499 PolarHBondContact O-ND2 2.86Å; Y466-N499 HydrophobicContact CD1-CB 4.32Å; Y466-N499 HydrophobicContact CE1-CB 3.75Å; L495-N499 WeakPolarHBondContact CD1-ND2 3.25Å; L495-N499 WeakPolarHBondContact O-CB 3.2Å; L495-N499 VanDerWaalsContact O-CG 3.32Å; L495-N499 PolarHBondContact O-N 3.24Å; L495-N499 PolarHBondContact O-ND2 3.21Å; A496-N499 PolarHBondContact O-N 2.63Å; G497-N499 PolarHBondContact O-N 3.38Å; N499-A501 VanDerWaalsContact C-N 3.33Å; N499-A501 PolarHBondContact O-N 3.25Å; N499-A502 PolarHBondContact O-N 3.41Å; N499-D503 WeakPolarHBondContact O-CB 3.4Å; N499-D503 PolarHBondContact O-N 3.09Å
500A97.9Very high80.3Confident0 Ų045.1 Ų45.10%025%0.252CS..Hα-helixtrans-61.3-42.5174.400000111.7V32 A224 V226 Y466 A496 G504V32-A500 HydrophobicContact CG1-CB 3.99Å; V32-A500 HydrophobicContact CG2-CB 4.14Å; A224-A500 HydrophobicContact CB-CB 3.85Å; V226-A500 HydrophobicContact CG2-CB 3.62Å; Y466-A500 HydrophobicContact CD2-CB 3.73Å; Y466-A500 HydrophobicContact CE2-CB 3.88Å; Y466-A500 HydrophobicContact CG-CB 4.14Å; A496-A500 WeakPolarHBondContact O-CB 3.22Å; A496-A500 PolarHBondContact O-N 2.77Å; A500-G504 PolarHBondContact O-N 3.43Å
501A95.2Very high77.2Confident9 Ų954.7 Ų54.77%0.07429%0.294CS..Hα-helixtrans-66.9-43.1175.900000112.7V32 A48 Q51 A53 G497 V498 N499 D503 G504 G505V32-A501 HydrophobicContact CG2-CB 4.19Å; A48-A501 HydrophobicContact CB-CB 4.07Å; Q51-A501 HydrophobicContact CB-CB 3.61Å; Q51-A501 HydrophobicContact CG-CB 4.02Å; A53-A501 HydrophobicContact CB-CB 3.71Å; G497-A501 WeakPolarHBondContact O-CB 3.46Å; G497-A501 PolarHBondContact O-N 3.37Å; G497-A501 VanDerWaalsContact O-N 3.09Å; V498-A501 PolarHBondContact O-N 2.89Å; N499-A501 VanDerWaalsContact C-N 3.33Å; N499-A501 PolarHBondContact O-N 3.25Å; A501-D503 PolarHBondContact O-N 3.43Å; A501-G504 PolarHBondContact O-N 2.7Å; A501-G505 PolarHBondContact O-N 3.33Å; A501-G505 VanDerWaalsContact O-N 3.11Å
502A92.8Very high74.2Confident56 Ų5657.7 Ų57.746%0.46331%0.313SS..Hα-helixtrans-64.5-38.2-18000000112.8V498 N499V498-A502 WeakPolarHBondContact O-CB 3.44Å; V498-A502 PolarHBondContact O-N 2.73Å; N499-A502 PolarHBondContact O-N 3.41Å
503D83.3Confident70.9Confident72 Ų7260.9 Ų60.939%0.38534%0.336SS..Hα-helixtrans-79.5-33.3177.5-74.6-33000112.1Y466 N499 A501Y466-D503 VanDerWaalsContact OH-CB 3.25Å; Y466-D503 WeakPolarHBondContact OH-CB 3.44Å; Y466-D503 VanDerWaalsContact OH-CG 3.29Å; Y466-D503 PolarHBondContact OH-OD2 2.88Å; N499-D503 WeakPolarHBondContact O-CB 3.4Å; N499-D503 PolarHBondContact O-N 3.09Å; A501-D503 PolarHBondContact O-N 3.43Å
504G64.8Low67.8Low4 Ų469.7 Ų69.74%0.04137%0.374CS..Hα-helixtrans-67.5-35.2178.100000114.1A500 A501 K506A500-G504 PolarHBondContact O-N 3.43Å; A501-G504 PolarHBondContact O-N 2.7Å; G504-K506 CarbonylContact O-C 3.59Å; G504-K506 PolarHBondContact O-N 2.77Å
505G53.4Low64.6Low55 Ų5579.9 Ų79.957%0.56741%0.409SS*.THydrogen-bonded Turntrans-59.1-9.6178.600000115.6A501 K507A501-G505 PolarHBondContact O-N 3.33Å; A501-G505 VanDerWaalsContact O-N 3.11Å; G505-K507 PolarHBondContact O-N 2.87Å
506K50.8Low61.4Low164 Ų16485.3 Ų85.371%0.71343%0.434SS*.SBendtrans-80.162.8167.4-63179.4-174.6168.10110.2G504 L508G504-K506 CarbonylContact O-C 3.59Å; G504-K506 PolarHBondContact O-N 2.77Å; K506-L508 PolarHBondContact O-N 3.44Å; K506-L508 VanDerWaalsContact O-N 3.1Å
507K45.9Very low58.4Low161 Ų16188 Ų8870%0.745%0.445SS*.  trans-4.191.9175.4-71.1-177.6170.3-177.20114.9G505 H509G505-K507 PolarHBondContact O-N 2.87Å; K507-H509 PolarHBondContact O-N 3.1Å; K507-H509 VanDerWaalsContact O-N 3.09Å
508L42.2Very low55.4Low57 Ų5794.9 Ų94.930%0.29848%0.482SS..  trans-82.345.2164.5-103.6149.1000109.9E202 D223 K506 T510E202-L508 WeakPolarHBondContact OE2-CD2 3.5Å; D223-L508 VanDerWaalsContact OD1-CB 3.28Å; D223-L508 WeakPolarHBondContact OD1-CB 3.12Å; K506-L508 PolarHBondContact O-N 3.44Å; K506-L508 VanDerWaalsContact O-N 3.1Å; L508-T510 PolarHBondContact O-N 3.37Å
509H38.8Very low52.3Low132 Ų13295.7 Ų95.761%0.61149%0.493SS*.  trans-79.560.5174.8-61.2-36.4000111.3K507K507-H509 PolarHBondContact O-N 3.1Å; K507-H509 VanDerWaalsContact O-N 3.09Å
510T35.8Very low49.2Very low108 Ų10898.6 Ų98.666%0.66351%0.512SS*.SBendtrans-102.4109.4147.255.40000105.4L508 P512L508-T510 PolarHBondContact O-N 3.37Å; T510-P512 VanDerWaalsContact O-CD 3.26Å; T510-P512 WeakPolarHBondContact O-CD 3.47Å
511K33.9Very low45.9Very low201 Ų201104.2 Ų104.287%0.87454%0.539SS*.  trans-45.6115.6171-89.9-178173.5179.30106.6S513K511-S513 PolarHBondContact O-N 2.9Å
512P35Very low42.9Very low67 Ų67110.7 Ų110.744%0.43557%0.572SS.*  trans-61.8116.2-17921.7-29.9000106.9T510 F514 F517T510-P512 VanDerWaalsContact O-CD 3.26Å; T510-P512 WeakPolarHBondContact O-CD 3.47Å; P512-F514 PolarHBondContact O-N 3.41Å; P512-F517 HydrophobicContact CB-CE2 3.84Å; P512-F517 HydrophobicContact CB-CZ 3.59Å; P512-F517 HydrophobicContact CG-CE2 4.34Å; P512-F517 HydrophobicContact CG-CZ 3.8Å
513S29.5Very low39.8Very low76 Ų76116.6 Ų116.653%0.53159%0.588SS.*  trans-61.3124.7175.979.70000106.4K511 R515 Q516K511-S513 PolarHBondContact O-N 2.9Å; S513-R515 PolarHBondContact O-N 3.29Å; S513-Q516 PolarHBondContact O-N 3.06Å
514F34.3Very low37.1Very low185 Ų185119.6 Ų119.681%0.81161%0.608SS**G310 helixtrans-53.3-9.5-179.4-105.1-92.1000114.3P512P512-F514 PolarHBondContact O-N 3.41Å
515R32Very low35.4Very low239 Ų239123.1 Ų123.190%0.90264%0.638SS**G310 helixtrans-85.11.9-177.4-73.8-168.4175-172.4-0.9116.1S513S513-R515 PolarHBondContact O-N 3.29Å
516Q30.7Very low34.1Very low137 Ų137130.4 Ų130.464%0.6465%0.654SS**G310 helixtrans-132.930.6177.5-85.8-172.5-14.200114.1S513 D518S513-Q516 PolarHBondContact O-N 3.06Å; Q516-D518 PolarHBondContact O-N 2.85Å
517F34.8Very low33.1Very low55 Ų55131.6 Ų131.624%0.24166%0.662CS.*  trans-88.399.3166.3-70.1-95000108.6V198 V219 P512 A519V198-F517 HydrophobicContact CB-CE1 4.37Å; V198-F517 HydrophobicContact CG1-CD1 3.82Å; V198-F517 HydrophobicContact CG1-CE1 3.32Å; V198-F517 HydrophobicContact CG1-CZ 4.39Å; V198-F517 HydrophobicContact CG2-CD1 4.41Å; V198-F517 HydrophobicContact CG2-CE1 4.19Å; V219-F517 HydrophobicContact CG1-CE1 4.34Å; P512-F517 HydrophobicContact CB-CE2 3.84Å; P512-F517 HydrophobicContact CB-CZ 3.59Å; P512-F517 HydrophobicContact CG-CE2 4.34Å; P512-F517 HydrophobicContact CG-CZ 3.8Å; F517-A519 HydrophobicContact CB-CB 4.46Å; F517-A519 PolarHBondContact O-N 3.26Å
518D36.2Very low32.3Very low145 Ų145131.3 Ų131.378%0.77567%0.666SS**  trans-71.361.7154-68.9-29.7000107.9Q516 V520Q516-D518 PolarHBondContact O-N 2.85Å; D518-V520 PolarHBondContact O-N 3.15Å
519A33.7Very low31.9Very low57 Ų57132.6 Ų132.647%0.47169%0.694SS.*  trans-69.885.316000000105F517 M521F517-A519 HydrophobicContact CB-CB 4.46Å; F517-A519 PolarHBondContact O-N 3.26Å; A519-M521 PolarHBondContact O-N 2.89Å
520V31.6Very low31.4Very low90 Ų90133.6 Ų133.655%0.54570%0.703SS.*  trans-65.488.2171.4-179.60000106.4Y270 D518 L522Y270-V520 VanDerWaalsContact OH-CB 3.24Å; Y270-V520 WeakPolarHBondContact OH-CB 3.36Å; Y270-V520 VanDerWaalsContact OH-CG2 3.31Å; Y270-V520 WeakPolarHBondContact OH-CG2 3.47Å; D518-V520 PolarHBondContact O-N 3.15Å; V520-L522 PolarHBondContact O-N 3.22Å
521M29Very low31.2Very low119 Ų119137 Ų13759%0.58671%0.711SS**  trans-65.3118.6174.6-79.7-90.1-92.600107.9A519 F523A519-M521 PolarHBondContact O-N 2.89Å; M521-F523 PolarHBondContact O-N 3.4Å; M521-F523 VanDerWaalsContact O-N 3.08Å
522L31.4Very low31.2Very low145 Ų145140.5 Ų140.576%0.75973%0.727SS**  trans-56.3108.7166.7-81.3154.7000109.7V520 T524V520-L522 PolarHBondContact O-N 3.22Å; L522-T524 HydrophobicContact CD2-CG2 4.28Å
523F28.1Very low31Very low180 Ų180144.2 Ų144.279%0.78974%0.741SS**  trans-105.597.5143.7-81.5-80.8000107.1M521 A525M521-F523 PolarHBondContact O-N 3.4Å; M521-F523 VanDerWaalsContact O-N 3.08Å; F523-A525 PolarHBondContact O-N 3.37Å
524T28.2Very low31.1Very low134 Ų134147.8 Ų147.882%0.82275%0.752SS**  trans-68.882.5158.742.30000107.7L522L522-T524 HydrophobicContact CD2-CG2 4.28Å
525A28.2Very low30.9Very low79 Ų79145.7 Ų145.765%0.65375%0.749SS**  trans-134.860.5168.200000108.3F523F523-A525 PolarHBondContact O-N 3.37Å
526F27.1Very low30.8Very low207 Ų207140.2 Ų140.291%0.90874%0.74SS**  trans-134.176.2169.8-107.8-84.3000107.6
527E29.1Very low30.9Very low190 Ų190140.4 Ų140.489%0.88875%0.746SS**SBendtrans-170.945.7156-110.4174.1-153.900111.6
528I29.6Very low30.6Very low154 Ų154146.1 Ų146.179%0.7978%0.78SS**  trans-137.967.1156.6-44.3175.6000107.4L530I528-L530 HydrophobicContact CG2-CD1 4.26Å; I528-L530 HydrophobicContact CG2-CG 4.27Å; I528-L530 PolarHBondContact O-N 3.32Å
529G32.2Very low30.2Very low85 Ų85146.2 Ų146.288%0.87678%0.78SS**  trans-72.679.9164.900000109.2
530L29.9Very low29.9Very low152 Ų152153.1 Ų153.180%0.79680%0.804SS**  trans-70.1119.2149.7-80.1158.7000107I528I528-L530 HydrophobicContact CG2-CD1 4.26Å; I528-L530 HydrophobicContact CG2-CG 4.27Å; I528-L530 PolarHBondContact O-N 3.32Å
531E31.5Very low29.8Very low180 Ų180158.3 Ų158.384%0.84183%0.825SS**  trans-157110151.4-115.1178-162.100111.3
532K33.3Very low29.8Very low275 Ų275161.9 Ų161.9100%1.19685%0.847SS**  trans63.80153.6-66.3-179.4-179.5172.80119.6

Retrieved 532 of 532 residues in 108.4 ms (Link to these results)