A0A077YVK6_TRITR Loading...

Dipeptidyl aminopeptidase

AlphaFold DB , UniProt , Accession A0A077YVK6, Species TRITR (Trichuris trichiura, Whipworm), Gene n/a, Length 633 aa.

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Site Residue pLDDT pLDDT confidence pLDDT10 pLDDT10 confidence SASA SASA [Ų] SASA10 SASA10 [Ų] RSA RSA unformatted RSA10 RSA10 unformatted Surface Surface10 (not used) Disorder (not used) Disorder Sec. str. Secondary structure Isomer Phi (φ) Psi (ψ) Omega (ω) Chi 1 (χ1) Chi 2 (χ2) Chi 3 (χ3) Chi 4 (χ4) Chi 5 (χ5) Tau (τ) Contacts (colored by PAE) Contact details
1M68.9Low81.8Confident156 Ų15684.7 Ų84.777%0.76843%0.429SS*.  0153.40-65.2-178.4-67.100107.7I9M1-I9 HydrophobicContact CB-CB 4.39Å; M1-I9 HydrophobicContact CB-CD1 4.25Å; M1-I9 PolarHBondContact O-N 3.38Å
2R76.1Confident82.5Confident130 Ų13081.1 Ų81.149%0.49141%0.406SS..BIsolated β-bridgetrans-115.5150.2172.5-67-175179-1198.2110.5D6 D7 L8R2-D6 WeakPolarHBondContact CD-O 3.42Å; R2-D6 WeakPolarHBondContact CD-OD1 3.45Å; R2-D6 IonicContact CZ-OD2 2.97Å; R2-D6 IonicContact NE-OD1 3.67Å; R2-D6 PolarHBondContact NH1-O 2.99Å; R2-D6 IonicContact NH1-OD1 2.73Å; R2-D6 IonicContact NH1-OD2 3.28Å; R2-D6 PolarHBondContact NH1-OD2 2.6Å; R2-D7 CarbonylContact C-O 3.54Å; R2-D7 WeakPolarHBondContact CA-O 3.27Å; R2-L8 HydrophobicContact CG-CD2 3.94Å; R2-L8 HydrophobicContact CG-CG 4.41Å
3D82.4Confident83Confident36 Ų3682.3 Ų82.319%0.19340%0.403CS..  trans-89.3-173.7174.473.49.8000111.9N5 D6 D7 I9 S30D3-N5 PolarHBondContact O-N 3.43Å; D3-N5 WeakPolarHBondContact OD1-CA 3.47Å; D3-N5 WeakPolarHBondContact OD1-CB 3.38Å; D3-N5 PolarHBondContact OD1-N 3.12Å; D3-D6 PolarHBondContact O-N 3.08Å; D3-D6 PolarHBondContact OD1-N 3.43Å; D3-D7 PolarHBondContact N-O 3.16Å; D3-D7 WeakPolarHBondContact OD1-CB 3.09Å; D3-D7 PolarHBondContact OD1-N 3.2Å; D3-I9 HydrophobicContact CB-CD1 3.89Å; D3-I9 HydrophobicContact CB-CG1 3.95Å; D3-S30 WeakPolarHBondContact OD2-CB 3.47Å; D3-S30 PolarHBondContact OD2-OG 2.7Å
4D81Confident83.4Confident175 Ų17590.1 Ų90.194%0.93643%0.425SS*.THydrogen-bonded Turntrans-64.3-17.7-178.8-64.4-23.3000113.6D6D4-D6 VanDerWaalsContact C-N 3.33Å
5N82.5Confident83.7Confident126 Ų12688.6 Ų88.667%0.67442%0.421SS*.THydrogen-bonded Turntrans-936.3174.7-59.6-50.4000112.6D3 D7D3-N5 PolarHBondContact O-N 3.43Å; D3-N5 WeakPolarHBondContact OD1-CA 3.47Å; D3-N5 WeakPolarHBondContact OD1-CB 3.38Å; D3-N5 PolarHBondContact OD1-N 3.12Å; N5-D7 PolarHBondContact O-N 2.88Å
6D78.9Confident83.8Confident99 Ų9983.3 Ų83.353%0.52940%0.396SS..SBendtrans65.214-170-157.355.6000113.1R2 D3 D4R2-D6 WeakPolarHBondContact CD-O 3.42Å; R2-D6 WeakPolarHBondContact CD-OD1 3.45Å; R2-D6 IonicContact CZ-OD2 2.97Å; R2-D6 IonicContact NE-OD1 3.67Å; R2-D6 PolarHBondContact NH1-O 2.99Å; R2-D6 IonicContact NH1-OD1 2.73Å; R2-D6 IonicContact NH1-OD2 3.28Å; R2-D6 PolarHBondContact NH1-OD2 2.6Å; D3-D6 PolarHBondContact O-N 3.08Å; D3-D6 PolarHBondContact OD1-N 3.43Å; D4-D6 VanDerWaalsContact C-N 3.33Å
7D82.8Confident83.9Confident43 Ų4379.5 Ų79.523%0.2338%0.38CS..PPolyproline II helixtrans-76.8146.9176.7-71.4-18.5000110.1R2 D3 N5 P32R2-D7 CarbonylContact C-O 3.54Å; R2-D7 WeakPolarHBondContact CA-O 3.27Å; D3-D7 PolarHBondContact N-O 3.16Å; D3-D7 WeakPolarHBondContact OD1-CB 3.09Å; D3-D7 PolarHBondContact OD1-N 3.2Å; N5-D7 PolarHBondContact O-N 2.88Å; D7-P32 WeakPolarHBondContact OD1-CA 3.49Å
8L83.1Confident83.9Confident46 Ų4678.3 Ų78.324%0.24137%0.373CS..EExtended strand (participates in β ladder)trans-74.1134.3177.6-77.9162.3000110.9R2 C31 Q34R2-L8 HydrophobicContact CG-CD2 3.94Å; R2-L8 HydrophobicContact CG-CG 4.41Å; L8-C31 PolarHBondContact N-O 3.22Å; L8-C31 PolarHBondContact O-N 3.41Å; L8-Q34 VanDerWaalsContact CD1-CA 3.41Å; L8-Q34 HydrophobicContact CD1-CB 3.85Å; L8-Q34 HydrophobicContact CD1-CG 3.97Å
9I87.1Confident84Confident50 Ų5082.6 Ų82.626%0.25639%0.392SS..EExtended strand (participates in β ladder)trans-94120.7178.4-52.1176.7000109M1 D3 C11 C28M1-I9 HydrophobicContact CB-CB 4.39Å; M1-I9 HydrophobicContact CB-CD1 4.25Å; M1-I9 PolarHBondContact O-N 3.38Å; D3-I9 HydrophobicContact CB-CD1 3.89Å; D3-I9 HydrophobicContact CB-CG1 3.95Å; I9-C11 VanDerWaalsContact CG2-SG 3.58Å; I9-C28 HydrophobicContact CG2-CB 3.62Å
10F88.1Confident84Confident35 Ų3582.7 Ų82.715%0.15440%0.395CS..EExtended strand (participates in β ladder)trans-98.5124.1170.8-169.7-93.8000109.6W12 C28 V29 Y38 I47 M49 L62F10-W12 AromaticContact CD1-CE3 3.86Å; F10-W12 HydrophobicContact CD1-CE3 3.86Å; F10-W12 HydrophobicContact CD1-CZ3 4.18Å; F10-W12 HydrophobicContact CE1-CE3 4.18Å; F10-C28 CarbonylContact O-C 3.56Å; F10-C28 WeakPolarHBondContact O-CA 3.25Å; F10-V29 HydrophobicContact CB-CG1 4.2Å; F10-V29 PolarHBondContact N-O 3.3Å; F10-V29 PolarHBondContact O-N 3.33Å; F10-Y38 AromaticContact CE2-CD1 3.98Å; F10-Y38 HydrophobicContact CE2-CD1 3.98Å; F10-Y38 HydrophobicContact CE2-CD2 4.43Å; F10-Y38 HydrophobicContact CE2-CE1 4.18Å; F10-Y38 HydrophobicContact CE2-CG 4.12Å; F10-Y38 HydrophobicContact CZ-CD1 4.49Å; F10-Y38 HydrophobicContact CZ-CD2 4.14Å; F10-Y38 HydrophobicContact CZ-CE2 4.33Å; F10-Y38 HydrophobicContact CZ-CG 4.23Å; F10-I47 HydrophobicContact CE1-CD1 4.41Å; F10-M49 HydrophobicContact CB-CE 4.09Å; F10-M49 HydrophobicContact CD1-CE 4.26Å; F10-M49 HydrophobicContact CD1-SD 4.48Å; F10-M49 HydrophobicContact CD2-CE 3.61Å; F10-M49 HydrophobicContact CE2-CE 4.06Å; F10-M49 HydrophobicContact CG-CE 3.72Å; F10-L62 HydrophobicContact CD1-CD2 3.46Å; F10-L62 VanDerWaalsContact CD1-CD2 3.46Å; F10-L62 HydrophobicContact CE1-CD2 3.5Å; F10-L62 VanDerWaalsContact CE1-CD2 3.5Å
11C89.3Confident83.7Confident36 Ų3684.5 Ų84.524%0.24341%0.407CS..EExtended strand (participates in β ladder)trans-124.3146.5-177-61.40000111.9I9 M26 T27 C28I9-C11 VanDerWaalsContact CG2-SG 3.58Å; C11-M26 HydrophobicContact CB-CG 3.89Å; C11-M26 HydrophobicContact CB-SD 4.05Å; C11-T27 CarbonylContact C-O 3.56Å; C11-T27 WeakPolarHBondContact CA-O 3.47Å; C11-C28 HydrophobicContact CB-CB 4.12Å; C11-C28 WeakPolarHBondContact CB-SG 3.21Å; C11-C28 WeakPolarHBondContact SG-CB 3.34Å; C11-C28 CovalentContact SG-SG 2.05Å; C11-C28 PolarHBondContact SG-SG 2.98Å
12W90.1Very high84.5Confident41 Ų4180.1 Ų80.116%0.15539%0.392CS..EExtended strand (participates in β ladder)trans-142161.3173.964.797.6000110.6F10 T27 V29 L62 P64 P69F10-W12 AromaticContact CD1-CE3 3.86Å; F10-W12 HydrophobicContact CD1-CE3 3.86Å; F10-W12 HydrophobicContact CD1-CZ3 4.18Å; F10-W12 HydrophobicContact CE1-CE3 4.18Å; W12-T27 HydrophobicContact CH2-CG2 3.86Å; W12-T27 HydrophobicContact CZ2-CG2 3.38Å; W12-T27 PolarHBondContact N-O 3.19Å; W12-T27 PolarHBondContact O-N 3.13Å; W12-V29 HydrophobicContact CH2-CB 4.29Å; W12-V29 HydrophobicContact CH2-CG1 4.4Å; W12-V29 HydrophobicContact CZ3-CB 4.18Å; W12-V29 HydrophobicContact CZ3-CG1 3.95Å; W12-L62 HydrophobicContact CE3-CD2 4.13Å; W12-L62 HydrophobicContact CH2-CD1 3.97Å; W12-L62 HydrophobicContact CH2-CD2 4.43Å; W12-L62 HydrophobicContact CZ3-CD1 4.15Å; W12-L62 HydrophobicContact CZ3-CD2 3.91Å; W12-P64 HydrophobicContact CD2-CB 4.08Å; W12-P64 VanDerWaalsContact CE2-CB 3.44Å; W12-P64 HydrophobicContact CG-CB 4.39Å; W12-P64 HydrophobicContact CZ2-CB 3.7Å; W12-P64 PolarHBondContact NE1-O 3.1Å; W12-P69 HydrophobicContact CH2-CB 3.52Å; W12-P69 HydrophobicContact CH2-CG 3.87Å; W12-P69 HydrophobicContact CZ2-CB 3.52Å; W12-P69 HydrophobicContact CZ2-CG 3.54Å
13R89.4Confident85Confident97 Ų9777.3 Ų77.337%0.36638%0.382SS..EExtended strand (participates in β ladder)trans-151.2156.1174.964.5-175.3179.4172.80.7110.3L15 Y23 D25R13-L15 PolarHBondContact O-N 3.2Å; R13-Y23 VanDerWaalsContact NE-CD1 3.32Å; R13-Y23 VanDerWaalsContact NH2-CE1 3.28Å; R13-D25 WeakPolarHBondContact CB-O 3.22Å
14R87.8Confident85.2Confident191 Ų19177 Ų7772%0.72139%0.387SS*.PPolyproline II helixtrans-69.3129.7172-172.5173.5176.7173-1.4109.7G24R14-G24 PolarHBondContact O-N 3.09Å
15L88.2Confident85.7Confident68 Ų6875.8 Ų75.836%0.35638%0.381SS..PPolyproline II helixtrans-76.2154.4175-62.7-176.9000111.5R13 Y23 L300 L313R13-L15 PolarHBondContact O-N 3.2Å; L15-Y23 HydrophobicContact CD2-CE1 4.23Å; L15-L300 HydrophobicContact CB-CD2 4.04Å; L15-L300 HydrophobicContact CD1-CD2 4.1Å; L15-L313 HydrophobicContact CD1-CD1 4.29Å; L15-L313 HydrophobicContact CD2-CD1 4.49Å; L15-L313 HydrophobicContact CD2-CD2 4Å
16P85.3Confident86.1Confident3 Ų375.3 Ų75.32%0.01938%0.376CS..PPolyproline II helixtrans-56160172.1-26.836.8000113.7N20 Y23 I311P16-N20 WeakPolarHBondContact CA-O 3.31Å; P16-Y23 HydrophobicContact CG-CD1 4.07Å; P16-Y23 HydrophobicContact CG-CD2 4.29Å; P16-Y23 HydrophobicContact CG-CE1 3.9Å; P16-Y23 HydrophobicContact CG-CE2 4.12Å; P16-Y23 HydrophobicContact CG-CG 4.26Å; P16-I311 HydrophobicContact CB-CD1 3.79Å; P16-I311 HydrophobicContact CB-CG2 4.2Å; P16-I311 HydrophobicContact CG-CG2 4.15Å
17T85.6Confident86.7Confident20 Ų2073.1 Ų73.112%0.12337%0.366CS..  trans-132.6171.9-179.455.20000110.1E19 N20T17-E19 VanDerWaalsContact C-N 3.26Å; T17-E19 PolarHBondContact O-N 2.79Å; T17-N20 PolarHBondContact N-O 3.48Å; T17-N20 CarbonylContact O-C 3.33Å; T17-N20 PolarHBondContact O-N 3.39Å; T17-N20 VanDerWaalsContact O-O 3.05Å; T17-N20 PolarHBondContact OG1-N 3.2Å; T17-N20 VanDerWaalsContact OG1-N 3.1Å; T17-N20 PolarHBondContact OG1-O 2.69Å
18F83.5Confident87.2Confident58 Ų5874.1 Ų74.125%0.25438%0.375SS..SBendtrans-57.6-40.4173.4-86.9-76000112.4L302 S304 R307 M309F18-L302 HydrophobicContact CD2-CB 3.88Å; F18-L302 HydrophobicContact CD2-CD1 4.09Å; F18-L302 HydrophobicContact CE2-CB 3.22Å; F18-L302 HydrophobicContact CE2-CD1 4.28Å; F18-L302 HydrophobicContact CE2-CG 4.35Å; F18-L302 HydrophobicContact CZ-CB 3.64Å; F18-L302 WeakPolarHBondContact CZ-O 3.36Å; F18-S304 VanDerWaalsContact CE2-CB 3.43Å; F18-R307 HydrophobicContact CE1-CB 4.22Å; F18-R307 WeakPolarHBondContact CZ-O 3.37Å; F18-M309 HydrophobicContact CD1-CE 3.45Å; F18-M309 VanDerWaalsContact CD1-CE 3.45Å; F18-M309 HydrophobicContact CD1-CG 3.97Å; F18-M309 HydrophobicContact CD1-SD 3.48Å; F18-M309 WeakPolarHBondContact CD1-SD 3.36Å; F18-M309 HydrophobicContact CE1-CB 3.98Å; F18-M309 HydrophobicContact CE1-CE 3.64Å; F18-M309 HydrophobicContact CE1-CG 3.38Å; F18-M309 HydrophobicContact CE1-SD 3.58Å; F18-M309 VanDerWaalsContact CE1-SD 3.58Å; F18-M309 HydrophobicContact CE2-CG 4.39Å; F18-M309 HydrophobicContact CG-CE 4.42Å; F18-M309 HydrophobicContact CG-SD 4.02Å; F18-M309 HydrophobicContact CZ-CB 4.38Å; F18-M309 HydrophobicContact CZ-CG 3.61Å; F18-M309 HydrophobicContact CZ-SD 4.19Å
19E85.9Confident87.6Confident160 Ų16073.2 Ų73.275%0.74837%0.372SS*.SBendtrans-84-24.1-176.1-54.781.8-173.300112.8T17T17-E19 VanDerWaalsContact C-N 3.26Å; T17-E19 PolarHBondContact O-N 2.79Å
20N84.6Confident87.7Confident83 Ų8373.2 Ų73.244%0.44438%0.376SS..  trans-138.1110.8-179.3-176.29.1000111.6P16 T17 S22P16-N20 WeakPolarHBondContact CA-O 3.31Å; T17-N20 PolarHBondContact N-O 3.48Å; T17-N20 CarbonylContact O-C 3.33Å; T17-N20 PolarHBondContact O-N 3.39Å; T17-N20 VanDerWaalsContact O-O 3.05Å; T17-N20 PolarHBondContact OG1-N 3.2Å; T17-N20 VanDerWaalsContact OG1-N 3.1Å; T17-N20 PolarHBondContact OG1-O 2.69Å; N20-S22 VanDerWaalsContact C-N 3.31Å; N20-S22 PolarHBondContact ND2-OG 2.69Å; N20-S22 VanDerWaalsContact ND2-OG 3.16Å; N20-S22 PolarHBondContact O-N 3.36Å; N20-S22 WeakPolarHBondContact OD1-CB 3.46Å; N20-S22 PolarHBondContact OD1-N 2.76Å; N20-S22 PolarHBondContact OD1-OG 3.38Å
21N76.8Confident87.8Confident121 Ų12171.6 Ų71.665%0.64737%0.369SS*.  trans-85.34.9-179.7-160.920.7000113.9
22S85.3Confident87.6Confident65 Ų6573.1 Ų73.146%0.45538%0.379SS..SBendtrans-87.3141.9176.575.70000111.7N20N20-S22 VanDerWaalsContact C-N 3.31Å; N20-S22 PolarHBondContact ND2-OG 2.69Å; N20-S22 VanDerWaalsContact ND2-OG 3.16Å; N20-S22 PolarHBondContact O-N 3.36Å; N20-S22 WeakPolarHBondContact OD1-CB 3.46Å; N20-S22 PolarHBondContact OD1-N 2.76Å; N20-S22 PolarHBondContact OD1-OG 3.38Å
23Y86.7Confident87.4Confident70 Ų7072.1 Ų72.128%0.27538%0.377SS..PPolyproline II helixtrans-65.3141.9163.5-70.7-83.5000109.8R13 L15 P16 F312 L313R13-Y23 VanDerWaalsContact NE-CD1 3.32Å; R13-Y23 VanDerWaalsContact NH2-CE1 3.28Å; L15-Y23 HydrophobicContact CD2-CE1 4.23Å; P16-Y23 HydrophobicContact CG-CD1 4.07Å; P16-Y23 HydrophobicContact CG-CD2 4.29Å; P16-Y23 HydrophobicContact CG-CE1 3.9Å; P16-Y23 HydrophobicContact CG-CE2 4.12Å; P16-Y23 HydrophobicContact CG-CG 4.26Å; Y23-F312 PolarHBondContact OH-O 2.83Å; Y23-L313 HydrophobicContact CE1-CD2 4.25Å; Y23-L313 WeakPolarHBondContact OH-CA 3.21Å
24G88Confident87Confident29 Ų2974.3 Ų74.330%0.29939%0.391SS..PPolyproline II helixtrans-68.7164.9164.500000111.1R14R14-G24 PolarHBondContact O-N 3.09Å
25D90.1Very high86.8Confident150 Ų15067 Ų6780%0.80237%0.366SS*.PPolyproline II helixtrans-58.1147.1172.8-63.6-37.4000110.8R13R13-D25 WeakPolarHBondContact CB-O 3.22Å
26M91.4Very high86.5Confident117 Ų11772 Ų7258%0.57638%0.38SS*.EExtended strand (participates in β ladder)trans-84.4122.4177.6-170140.957.700109.6C11C11-M26 HydrophobicContact CB-CG 3.89Å; C11-M26 HydrophobicContact CB-SD 4.05Å
27T92.6Very high86.6Confident52 Ų5274.8 Ų74.832%0.31940%0.395SS..EExtended strand (participates in β ladder)trans-105.4139176.1-53.70000108.3C11 W12 P69C11-T27 CarbonylContact C-O 3.56Å; C11-T27 WeakPolarHBondContact CA-O 3.47Å; W12-T27 HydrophobicContact CH2-CG2 3.86Å; W12-T27 HydrophobicContact CZ2-CG2 3.38Å; W12-T27 PolarHBondContact N-O 3.19Å; W12-T27 PolarHBondContact O-N 3.13Å; T27-P69 HydrophobicContact CG2-CG 3.51Å
28C91.4Very high86.9Confident64 Ų6479.7 Ų79.743%0.43241%0.412SS..EExtended strand (participates in β ladder)trans-134.5154.8-178-56.80000111.8I9 F10 C11I9-C28 HydrophobicContact CG2-CB 3.62Å; F10-C28 CarbonylContact O-C 3.56Å; F10-C28 WeakPolarHBondContact O-CA 3.25Å; C11-C28 HydrophobicContact CB-CB 4.12Å; C11-C28 WeakPolarHBondContact CB-SG 3.21Å; C11-C28 WeakPolarHBondContact SG-CB 3.34Å; C11-C28 CovalentContact SG-SG 2.05Å; C11-C28 PolarHBondContact SG-SG 2.98Å
29V91.6Very high87.2Confident27 Ų2779.7 Ų79.716%0.16441%0.414CS..EExtended strand (participates in β ladder)trans-136.9143.4171.474.50000109.5F10 W12 L62 L71F10-V29 HydrophobicContact CB-CG1 4.2Å; F10-V29 PolarHBondContact N-O 3.3Å; F10-V29 PolarHBondContact O-N 3.33Å; W12-V29 HydrophobicContact CH2-CB 4.29Å; W12-V29 HydrophobicContact CH2-CG1 4.4Å; W12-V29 HydrophobicContact CZ3-CB 4.18Å; W12-V29 HydrophobicContact CZ3-CG1 3.95Å; V29-L62 HydrophobicContact CG1-CD1 3.97Å; V29-L71 HydrophobicContact CG1-CB 4.36Å; V29-L71 HydrophobicContact CG1-CD2 4.23Å; V29-L71 HydrophobicContact CG2-CB 3.86Å; V29-L71 HydrophobicContact CG2-CD2 4.41Å
30S91Very high87.4Confident50 Ų5077.4 Ų77.435%0.3540%0.399SS..EExtended strand (participates in β ladder)trans-79.6138.7172.1-58.50000110.4D3 L71D3-S30 WeakPolarHBondContact OD2-CB 3.47Å; D3-S30 PolarHBondContact OD2-OG 2.7Å; S30-L71 WeakPolarHBondContact O-CD2 3.26Å
31C88.3Confident87.7Confident1 Ų173.6 Ų73.61%0.00738%0.379CS..EExtended strand (participates in β ladder)trans-127.4123.3174.1-174.70000108.9L8 D33 I35 L71L8-C31 PolarHBondContact N-O 3.22Å; L8-C31 PolarHBondContact O-N 3.41Å; C31-D33 PolarHBondContact O-N 3.16Å; C31-D33 VanDerWaalsContact O-N 3.13Å; C31-I35 VanDerWaalsContact SG-CD1 3.56Å; C31-L71 HydrophobicContact CB-CD2 3.85Å
32P86.9Confident88.2Confident68 Ų6870.8 Ų70.844%0.44236%0.361SS..SBendtrans-73.8-2.8-177.631.7-37000113.5D7 W60D7-P32 WeakPolarHBondContact OD1-CA 3.49Å; P32-W60 HydrophobicContact CG-CH2 3.61Å; P32-W60 HydrophobicContact CG-CZ2 3.78Å
33D85.1Confident88.3Confident21 Ų2169.8 Ų69.811%0.11235%0.351CS..SBendtrans-114.1148.8-179-76-47.2000112.2C31 I35 A51 R58 W60C31-D33 PolarHBondContact O-N 3.16Å; C31-D33 VanDerWaalsContact O-N 3.13Å; D33-I35 PolarHBondContact O-N 3.45Å; D33-I35 VanDerWaalsContact O-N 3.07Å; D33-A51 HydrophobicContact CB-CB 3.52Å; D33-R58 IonicContact OD1-CZ 2.74Å; D33-R58 IonicContact OD1-NE 3.29Å; D33-R58 IonicContact OD1-NH1 3.16Å; D33-R58 PolarHBondContact OD1-NH1 3.42Å; D33-R58 WeakPolarHBondContact OD2-CD 3.17Å; D33-R58 IonicContact OD2-NE 3.77Å; D33-R58 IonicContact OD2-NH1 2.75Å; D33-R58 PolarHBondContact OD2-NH1 2.94Å; D33-W60 VanDerWaalsContact OD2-CE2 3.24Å; D33-W60 WeakPolarHBondContact OD2-CZ2 3.17Å; D33-W60 PolarHBondContact OD2-NE1 3.45Å
34Q80.4Confident88.1Confident143 Ų14371.9 Ų71.967%0.66837%0.367SS*.  trans-70.6102.7162.5-169.4173.5-1.800110.6L8 W36 A51L8-Q34 VanDerWaalsContact CD1-CA 3.41Å; L8-Q34 HydrophobicContact CD1-CB 3.85Å; L8-Q34 HydrophobicContact CD1-CG 3.97Å; Q34-W36 PolarHBondContact O-N 3.13Å; Q34-A51 WeakPolarHBondContact O-CA 3.31Å; Q34-A51 VanDerWaalsContact O-CB 3.24Å; Q34-A51 WeakPolarHBondContact O-CB 3.25Å
35I84.9Confident88.2Confident38 Ų3878.7 Ų78.720%0.19538%0.383CS..EExtended strand (participates in β ladder)trans-67.8119.7174.1-56.4-58.1000108.4C31 D33 D37 M49 A51C31-I35 VanDerWaalsContact SG-CD1 3.56Å; D33-I35 PolarHBondContact O-N 3.45Å; D33-I35 VanDerWaalsContact O-N 3.07Å; I35-D37 VanDerWaalsContact CG2-O 3.31Å; I35-D37 WeakPolarHBondContact CG2-O 3.28Å; I35-M49 HydrophobicContact CB-CE 4.43Å; I35-M49 HydrophobicContact CD1-CB 4.02Å; I35-M49 HydrophobicContact CD1-CE 3.9Å; I35-M49 HydrophobicContact CG1-CE 3.59Å; I35-M49 HydrophobicContact CG2-CB 4.14Å; I35-M49 HydrophobicContact CG2-CE 4.19Å; I35-A51 HydrophobicContact CD1-CB 4.42Å
36W82.1Confident88.3Confident172 Ų17271.7 Ų71.765%0.65235%0.346SS*.EExtended strand (participates in β ladder)trans-77-40.1175.6-175.9-91.1000110.3Q34 Y50 K52Q34-W36 PolarHBondContact O-N 3.13Å; W36-Y50 HydrophobicContact CB-CD2 4.14Å; W36-Y50 HydrophobicContact CB-CE2 3.9Å; W36-Y50 AromaticContact CD1-CE2 3.45Å; W36-Y50 VanDerWaalsContact CD1-CE2 3.45Å; W36-Y50 AromaticContact CD1-CZ 3.73Å; W36-Y50 AromaticContact CG-CE2 3.96Å; W36-Y50 HydrophobicContact CG-CE2 3.96Å; W36-Y50 PolarHBondContact N-O 3.25Å; W36-K52 HydrophobicContact CB-CB 4.24Å; W36-K52 HydrophobicContact CG-CB 4.32Å
37D87.1Confident88.4Confident61 Ų6166.3 Ų66.333%0.32632%0.32SS..EExtended strand (participates in β ladder)trans-165.9162.9-174.8-177.821.1000110.7I35 Y50I35-D37 VanDerWaalsContact CG2-O 3.31Å; I35-D37 WeakPolarHBondContact CG2-O 3.28Å; D37-Y50 HydrophobicContact CB-CD1 4.23Å; D37-Y50 HydrophobicContact CB-CE1 3.44Å; D37-Y50 VanDerWaalsContact CB-CE1 3.44Å; D37-Y50 HydrophobicContact CB-CE2 4.25Å; D37-Y50 VanDerWaalsContact CB-CZ 3.43Å; D37-Y50 VanDerWaalsContact CB-OH 3.29Å; D37-Y50 WeakPolarHBondContact CB-OH 3.46Å; D37-Y50 PolarHBondContact N-O 2.84Å; D37-Y50 PolarHBondContact O-N 3.11Å; D37-Y50 WeakPolarHBondContact OD2-CE1 3.36Å; D37-Y50 PolarHBondContact OD2-OH 3.08Å
38Y90.8Very high88.5Confident123 Ų12363.9 Ų63.948%0.48231%0.305SS..EExtended strand (participates in β ladder)trans-150147.3-176.364.2-87.2000112F10 I47 I48F10-Y38 AromaticContact CE2-CD1 3.98Å; F10-Y38 HydrophobicContact CE2-CD1 3.98Å; F10-Y38 HydrophobicContact CE2-CD2 4.43Å; F10-Y38 HydrophobicContact CE2-CE1 4.18Å; F10-Y38 HydrophobicContact CE2-CG 4.12Å; F10-Y38 HydrophobicContact CZ-CD1 4.49Å; F10-Y38 HydrophobicContact CZ-CD2 4.14Å; F10-Y38 HydrophobicContact CZ-CE2 4.33Å; F10-Y38 HydrophobicContact CZ-CG 4.23Å; Y38-I47 HydrophobicContact CD2-CG2 4.24Å; Y38-I48 CarbonylContact C-O 3.57Å; Y38-I48 VanDerWaalsContact CA-O 3.22Å; Y38-I48 WeakPolarHBondContact CA-O 3.49Å
39L90.4Very high88.5Confident58 Ų5860.8 Ų60.830%0.30428%0.284SS..EExtended strand (participates in β ladder)trans-141.1142.9-176.4-59.5162.3000110.7I47 I48 L85 L87L39-I47 CarbonylContact O-C 3.55Å; L39-I47 WeakPolarHBondContact O-CA 3.29Å; L39-I48 HydrophobicContact CB-CG2 3.89Å; L39-I48 PolarHBondContact N-O 3.33Å; L39-I48 WeakPolarHBondContact O-CG2 3.26Å; L39-I48 PolarHBondContact O-N 3.48Å; L39-L85 HydrophobicContact CD1-CD2 3.58Å; L39-L87 HydrophobicContact CB-CD1 3.89Å; L39-L87 HydrophobicContact CD1-CD1 4.36Å; L39-L87 HydrophobicContact CD1-CG 4.36Å
40W90Very high88.4Confident113 Ų11361 Ų6143%0.42828%0.282SS..EExtended strand (participates in β ladder)trans-73131.4168.2-78.192.6000110.3I47 P64 F65 L87W40-I47 HydrophobicContact CD2-CD1 4.32Å; W40-I47 HydrophobicContact CD2-CG1 3.72Å; W40-I47 HydrophobicContact CE3-CG1 3.75Å; W40-I47 HydrophobicContact CG-CG1 4.36Å; W40-I47 HydrophobicContact CH2-CD1 3.9Å; W40-I47 HydrophobicContact CH2-CG1 3.98Å; W40-I47 HydrophobicContact CZ2-CD1 3.65Å; W40-I47 HydrophobicContact CZ2-CG1 3.94Å; W40-I47 HydrophobicContact CZ3-CD1 4.32Å; W40-I47 HydrophobicContact CZ3-CG1 3.87Å; W40-P64 HydrophobicContact CH2-CG 3.81Å; W40-P64 HydrophobicContact CZ3-CG 4.1Å; W40-F65 AromaticContact CH2-CE2 3.82Å; W40-F65 HydrophobicContact CH2-CE2 3.82Å; W40-F65 AromaticContact CH2-CZ 3.94Å; W40-F65 HydrophobicContact CH2-CZ 3.94Å; W40-F65 AromaticContact CZ3-CE2 3.83Å; W40-F65 HydrophobicContact CZ3-CE2 3.83Å; W40-F65 HydrophobicContact CZ3-CZ 4.38Å; W40-L87 WeakPolarHBondContact O-CD1 3.37Å
41L91.5Very high88Confident3 Ų358.8 Ų58.82%0.01627%0.267CS..  trans-70.8155.6167.6-62.1-170.4000110.4D43 N44 S46 I48 L61 L87 V95 V114L41-D43 PolarHBondContact O-N 3.15Å; L41-D43 VanDerWaalsContact O-N 3.09Å; L41-N44 PolarHBondContact O-N 3.46Å; L41-S46 PolarHBondContact N-O 2.88Å; L41-I48 HydrophobicContact CD2-CB 4.05Å; L41-I48 HydrophobicContact CD2-CG2 3.85Å; L41-L61 HydrophobicContact CD1-CD1 3.93Å; L41-L87 HydrophobicContact CD2-CD2 3.72Å; L41-V95 HydrophobicContact CD2-CG1 4.07Å; L41-V114 HydrophobicContact CD1-CG1 4.44Å; L41-V114 HydrophobicContact CD1-CG2 3.75Å
42H87.4Confident87.3Confident62 Ų6263.4 Ų63.429%0.28729%0.287SS..THydrogen-bonded Turntrans-70.7-2.4-180-70.5-62.5000114.1N44 S88 I89 P92H42-N44 PolarHBondContact O-N 3.07Å; H42-S88 PolarHBondContact CD2-O 3.19Å; H42-I89 HydrophobicContact CB-CG2 4.43Å; H42-I89 PolarHBondContact CD2-N 2.88Å; H42-I89 VanDerWaalsContact CD2-N 3.3Å; H42-I89 WeakPolarHBondContact CE1-CG2 3.4Å; H42-I89 WeakPolarHBondContact ND1-CG2 3.4Å; H42-I89 WeakPolarHBondContact NE2-CG2 3.11Å; H42-P92 HydrophobicContact CB-CB 4.33Å
43D85.8Confident86.3Confident43 Ų4361.8 Ų61.823%0.2328%0.283CS..THydrogen-bonded Turntrans-72.3-9.916768.56.9000113L41 R45 S46L41-D43 PolarHBondContact O-N 3.15Å; L41-D43 VanDerWaalsContact O-N 3.09Å; D43-R45 PolarHBondContact O-N 3.21Å; D43-R45 PolarHBondContact OD1-N 3.13Å; D43-S46 PolarHBondContact OD1-N 3.5Å; D43-S46 WeakPolarHBondContact OD2-CB 3.42Å; D43-S46 PolarHBondContact OD2-OG 3.44Å
44N83.8Confident85Confident114 Ų11469.1 Ų69.161%0.6131%0.31SS*.SBendtrans56.225.2-175.5-56.3-62.1000113.9L41 H42L41-N44 PolarHBondContact O-N 3.46Å; H42-N44 PolarHBondContact O-N 3.07Å
45R88.9Confident84.6Confident172 Ų17266.7 Ų66.765%0.64931%0.309SS*.SBendtrans-127.9-37.6-177.3-71.8-177.8177.1-165.6-1.5112.1D43 P64 F65D43-R45 PolarHBondContact O-N 3.21Å; D43-R45 PolarHBondContact OD1-N 3.13Å; R45-P64 WeakPolarHBondContact O-CD 3.19Å; R45-P64 WeakPolarHBondContact O-CG 3.38Å; R45-F65 WeakPolarHBondContact O-CD2 3.37Å
46S93.1Very high84.5Confident3 Ų365.2 Ų65.22%0.02130%0.302CS..  trans-109.9148.1-170.3-380000111.2L41 D43 L62 E63L41-S46 PolarHBondContact N-O 2.88Å; D43-S46 PolarHBondContact OD1-N 3.5Å; D43-S46 WeakPolarHBondContact OD2-CB 3.42Å; D43-S46 PolarHBondContact OD2-OG 3.44Å; S46-L62 WeakPolarHBondContact CA-O 3.44Å; S46-E63 PolarHBondContact OG-OE1 3.11Å; S46-E63 PolarHBondContact OG-OE2 3.14Å
47I93.8Very high84.7Confident4 Ų457.1 Ų57.12%0.02127%0.272CS..EExtended strand (participates in β ladder)trans-115.1123.2173.8-59.1168.9000107.7F10 Y38 L39 W40 M49 L62 P64F10-I47 HydrophobicContact CE1-CD1 4.41Å; Y38-I47 HydrophobicContact CD2-CG2 4.24Å; L39-I47 CarbonylContact O-C 3.55Å; L39-I47 WeakPolarHBondContact O-CA 3.29Å; W40-I47 HydrophobicContact CD2-CD1 4.32Å; W40-I47 HydrophobicContact CD2-CG1 3.72Å; W40-I47 HydrophobicContact CE3-CG1 3.75Å; W40-I47 HydrophobicContact CG-CG1 4.36Å; W40-I47 HydrophobicContact CH2-CD1 3.9Å; W40-I47 HydrophobicContact CH2-CG1 3.98Å; W40-I47 HydrophobicContact CZ2-CD1 3.65Å; W40-I47 HydrophobicContact CZ2-CG1 3.94Å; W40-I47 HydrophobicContact CZ3-CD1 4.32Å; W40-I47 HydrophobicContact CZ3-CG1 3.87Å; I47-M49 HydrophobicContact CG2-CG 3.85Å; I47-L62 HydrophobicContact CB-CB 4.18Å; I47-L62 HydrophobicContact CD1-CD2 4.14Å; I47-L62 PolarHBondContact N-O 3.11Å; I47-L62 PolarHBondContact O-N 2.76Å; I47-P64 HydrophobicContact CD1-CG 4.13Å; I47-P64 HydrophobicContact CG1-CG 4.43Å
48I93.6Very high84.9Confident1 Ų157.7 Ų57.71%0.00527%0.269CS..EExtended strand (participates in β ladder)trans-86.6132.4167.9-169.5164.3000108.6Y38 L39 L41 I59 W60 L85 L87 V95 V114Y38-I48 CarbonylContact C-O 3.57Å; Y38-I48 VanDerWaalsContact CA-O 3.22Å; Y38-I48 WeakPolarHBondContact CA-O 3.49Å; L39-I48 HydrophobicContact CB-CG2 3.89Å; L39-I48 PolarHBondContact N-O 3.33Å; L39-I48 WeakPolarHBondContact O-CG2 3.26Å; L39-I48 PolarHBondContact O-N 3.48Å; L41-I48 HydrophobicContact CD2-CB 4.05Å; L41-I48 HydrophobicContact CD2-CG2 3.85Å; I48-I59 HydrophobicContact CD1-CG2 3.63Å; I48-I59 HydrophobicContact CG1-CG2 3.63Å; I48-W60 WeakPolarHBondContact CA-O 3.49Å; I48-L85 HydrophobicContact CD1-CD1 3.99Å; I48-L87 HydrophobicContact CG2-CD2 4.33Å; I48-V95 HydrophobicContact CD1-CB 4.37Å; I48-V95 HydrophobicContact CD1-CG1 3.84Å; I48-V95 HydrophobicContact CD1-CG2 3.86Å; I48-V114 HydrophobicContact CD1-CG1 4.11Å
49M92.3Very high85Confident0 Ų051.9 Ų51.90%025%0.246CC..EExtended strand (participates in β ladder)trans-126.4137.3179.9-54.4166.86000107.4F10 I35 I47 I59 W60 L62 L71F10-M49 HydrophobicContact CB-CE 4.09Å; F10-M49 HydrophobicContact CD1-CE 4.26Å; F10-M49 HydrophobicContact CD1-SD 4.48Å; F10-M49 HydrophobicContact CD2-CE 3.61Å; F10-M49 HydrophobicContact CE2-CE 4.06Å; F10-M49 HydrophobicContact CG-CE 3.72Å; I35-M49 HydrophobicContact CB-CE 4.43Å; I35-M49 HydrophobicContact CD1-CB 4.02Å; I35-M49 HydrophobicContact CD1-CE 3.9Å; I35-M49 HydrophobicContact CG1-CE 3.59Å; I35-M49 HydrophobicContact CG2-CB 4.14Å; I35-M49 HydrophobicContact CG2-CE 4.19Å; I47-M49 HydrophobicContact CG2-CG 3.85Å; M49-I59 WeakPolarHBondContact O-CA 3.41Å; M49-W60 HydrophobicContact CB-CB 4.24Å; M49-W60 PolarHBondContact N-O 2.97Å; M49-W60 PolarHBondContact O-N 3.32Å; M49-L62 HydrophobicContact SD-CB 3.72Å; M49-L62 HydrophobicContact SD-CD2 3.86Å; M49-L62 HydrophobicContact SD-CG 4.43Å; M49-L71 HydrophobicContact SD-CD1 3.97Å
50Y89.5Confident85.2Confident30 Ų3050.1 Ų50.112%0.11824%0.236CC..EExtended strand (participates in β ladder)trans-128140.7175.471.1-91.6000112.2W36 D37 R58 M82 L85W36-Y50 HydrophobicContact CB-CD2 4.14Å; W36-Y50 HydrophobicContact CB-CE2 3.9Å; W36-Y50 AromaticContact CD1-CE2 3.45Å; W36-Y50 VanDerWaalsContact CD1-CE2 3.45Å; W36-Y50 AromaticContact CD1-CZ 3.73Å; W36-Y50 AromaticContact CG-CE2 3.96Å; W36-Y50 HydrophobicContact CG-CE2 3.96Å; W36-Y50 PolarHBondContact N-O 3.25Å; D37-Y50 HydrophobicContact CB-CD1 4.23Å; D37-Y50 HydrophobicContact CB-CE1 3.44Å; D37-Y50 VanDerWaalsContact CB-CE1 3.44Å; D37-Y50 HydrophobicContact CB-CE2 4.25Å; D37-Y50 VanDerWaalsContact CB-CZ 3.43Å; D37-Y50 VanDerWaalsContact CB-OH 3.29Å; D37-Y50 WeakPolarHBondContact CB-OH 3.46Å; D37-Y50 PolarHBondContact N-O 2.84Å; D37-Y50 PolarHBondContact O-N 3.11Å; D37-Y50 WeakPolarHBondContact OD2-CE1 3.36Å; D37-Y50 PolarHBondContact OD2-OH 3.08Å; Y50-R58 CarbonylContact C-O 3.53Å; Y50-R58 VanDerWaalsContact CA-O 3.32Å; Y50-R58 WeakPolarHBondContact CA-O 3.15Å; Y50-M82 HydrophobicContact CD1-CE 4.13Å; Y50-M82 HydrophobicContact CD2-CE 3.2Å; Y50-M82 HydrophobicContact CE1-CE 4.45Å; Y50-M82 HydrophobicContact CE2-CE 3.61Å; Y50-M82 HydrophobicContact CG-CE 3.49Å; Y50-M82 VanDerWaalsContact CG-CE 3.49Å; Y50-L85 HydrophobicContact CD1-CD1 4.28Å
51A83.6Confident85.4Confident4 Ų445.5 Ų45.53%0.03322%0.219CC..EExtended strand (participates in β ladder)trans-109.6126175.200000108.6D33 Q34 I35 V57 R58D33-A51 HydrophobicContact CB-CB 3.52Å; Q34-A51 WeakPolarHBondContact O-CA 3.31Å; Q34-A51 VanDerWaalsContact O-CB 3.24Å; Q34-A51 WeakPolarHBondContact O-CB 3.25Å; I35-A51 HydrophobicContact CD1-CB 4.42Å; A51-V57 WeakPolarHBondContact O-CA 3.31Å; A51-R58 HydrophobicContact CB-CB 4.41Å; A51-R58 PolarHBondContact N-O 3.42Å; A51-R58 PolarHBondContact O-N 3.37Å
52K72.9Confident85.5Confident99 Ų9945.3 Ų45.343%0.4322%0.219SC..EExtended strand (participates in β ladder)trans-105.885.1174.9-171.7174.2176.8171.70108.4W36 M82W36-K52 HydrophobicContact CB-CB 4.24Å; W36-K52 HydrophobicContact CG-CB 4.32Å; K52-M82 PolarHBondContact NZ-O 3.38Å
53G65.1Low85.9Confident34 Ų3445 Ų4535%0.35122%0.217SC..  trans-85155.6173.700000112.1S55 A56G53-S55 PolarHBondContact O-N 2.93Å; G53-A56 WeakPolarHBondContact CA-O 3.34Å; G53-A56 PolarHBondContact N-O 3.24Å; G53-A56 PolarHBondContact O-N 2.97Å
54Y58.6Low86.2Confident175 Ų17543.3 Ų43.369%0.68621%0.208SC*.SBendtrans-55.5-36.8172-83.4-81000112.3R102 M534Y54-R102 PolarHBondContact O-NH1 3.04Å; Y54-R102 PolarHBondContact O-NH2 2.96Å; Y54-M534 HydrophobicContact CE1-CE 4.26Å
55S71.3Confident86.5Confident91 Ų9144.6 Ų44.664%0.63621%0.209SC*.SBendtrans-90.1-31.2-177.258.90000114.1G53 S78 R102G53-S55 PolarHBondContact O-N 2.93Å; S55-S78 WeakPolarHBondContact O-CA 3.17Å; S55-R102 VanDerWaalsContact C-NH2 3.32Å; S55-R102 PolarHBondContact O-NH2 2.95Å
56A83.4Confident86.7Confident8 Ų838.1 Ų38.17%0.06619%0.192CC..  trans-155.4150.3-17700000113.1G53 F77G53-A56 WeakPolarHBondContact CA-O 3.34Å; G53-A56 PolarHBondContact N-O 3.24Å; G53-A56 PolarHBondContact O-N 2.97Å; A56-F77 CarbonylContact C-O 3.58Å; A56-F77 WeakPolarHBondContact CA-O 3.22Å; A56-F77 WeakPolarHBondContact CB-O 3.41Å
57V86Confident86.5Confident1 Ų146 Ų461%0.00623%0.234CC..EExtended strand (participates in β ladder)trans-93129162.9177.50000107.9A51 S76 F77 M82A51-V57 WeakPolarHBondContact O-CA 3.31Å; V57-S76 CarbonylContact O-C 3.56Å; V57-S76 WeakPolarHBondContact O-CA 3.48Å; V57-F77 HydrophobicContact CB-CB 4.45Å; V57-F77 HydrophobicContact CB-CD2 4.18Å; V57-F77 HydrophobicContact CG1-CD2 4.26Å; V57-F77 PolarHBondContact N-O 3.38Å; V57-F77 PolarHBondContact O-N 3.36Å; V57-M82 HydrophobicContact CG1-CB 3.9Å; V57-M82 HydrophobicContact CG1-CE 4.06Å; V57-M82 HydrophobicContact CG1-SD 3.98Å; V57-M82 HydrophobicContact CG2-CB 4.01Å
58R91.6Very high86.4Confident74 Ų7450.7 Ų50.728%0.27927%0.265SS..EExtended strand (participates in β ladder)trans-125.9140.4177.6-65.9169.6-176.7178.52.4109.9D33 Y50 A51 I75D33-R58 IonicContact OD1-CZ 2.74Å; D33-R58 IonicContact OD1-NE 3.29Å; D33-R58 IonicContact OD1-NH1 3.16Å; D33-R58 PolarHBondContact OD1-NH1 3.42Å; D33-R58 WeakPolarHBondContact OD2-CD 3.17Å; D33-R58 IonicContact OD2-NE 3.77Å; D33-R58 IonicContact OD2-NH1 2.75Å; D33-R58 PolarHBondContact OD2-NH1 2.94Å; Y50-R58 CarbonylContact C-O 3.53Å; Y50-R58 VanDerWaalsContact CA-O 3.32Å; Y50-R58 WeakPolarHBondContact CA-O 3.15Å; A51-R58 HydrophobicContact CB-CB 4.41Å; A51-R58 PolarHBondContact N-O 3.42Å; A51-R58 PolarHBondContact O-N 3.37Å; R58-I75 WeakPolarHBondContact CA-O 3.42Å
59I93Very high86.3Confident0 Ų052.4 Ų52.40%028%0.276CS..EExtended strand (participates in β ladder)trans-120.5130.7177.1-59.6178.3000108.3I48 M49 I74 I75 F77 M82 L97 L112I48-I59 HydrophobicContact CD1-CG2 3.63Å; I48-I59 HydrophobicContact CG1-CG2 3.63Å; M49-I59 WeakPolarHBondContact O-CA 3.41Å; I59-I74 HydrophobicContact CG2-CD1 3.88Å; I59-I74 HydrophobicContact CG2-CG1 4.43Å; I59-I74 PolarHBondContact O-N 3.49Å; I59-I75 HydrophobicContact CB-CG2 3.96Å; I59-I75 HydrophobicContact CD1-CG2 4.06Å; I59-I75 HydrophobicContact CG1-CG2 4.2Å; I59-I75 PolarHBondContact N-O 2.99Å; I59-I75 PolarHBondContact O-N 3.13Å; I59-F77 HydrophobicContact CD1-CE2 4.41Å; I59-M82 HydrophobicContact CD1-SD 4.34Å; I59-L97 HydrophobicContact CD1-CD1 3.51Å; I59-L97 HydrophobicContact CD1-CD2 3.91Å; I59-L97 HydrophobicContact CD1-CG 4.37Å; I59-L112 HydrophobicContact CD1-CD2 3.82Å; I59-L112 HydrophobicContact CG2-CD2 4.3Å
60W93.6Very high86.4Confident22 Ų2257.6 Ų57.68%0.08330%0.3CS..EExtended strand (participates in β ladder)trans-118.7147.2-178.5-59.385.6000109.9P32 D33 I48 M49 L71 K72 M73P32-W60 HydrophobicContact CG-CH2 3.61Å; P32-W60 HydrophobicContact CG-CZ2 3.78Å; D33-W60 VanDerWaalsContact OD2-CE2 3.24Å; D33-W60 WeakPolarHBondContact OD2-CZ2 3.17Å; D33-W60 PolarHBondContact OD2-NE1 3.45Å; I48-W60 WeakPolarHBondContact CA-O 3.49Å; M49-W60 HydrophobicContact CB-CB 4.24Å; M49-W60 PolarHBondContact N-O 2.97Å; M49-W60 PolarHBondContact O-N 3.32Å; W60-L71 HydrophobicContact CB-CD1 4.04Å; W60-L71 HydrophobicContact CE3-CD1 4.37Å; W60-L71 HydrophobicContact CE3-CD2 4.16Å; W60-L71 HydrophobicContact CE3-CG 3.89Å; W60-L71 HydrophobicContact CZ3-CD2 4.46Å; W60-L71 HydrophobicContact CZ3-CG 4.44Å; W60-K72 CarbonylContact C-O 3.5Å; W60-K72 VanDerWaalsContact CA-O 3.3Å; W60-K72 WeakPolarHBondContact CA-O 3.19Å; W60-M73 HydrophobicContact CD2-CB 4.03Å; W60-M73 HydrophobicContact CD2-CG 4.27Å; W60-M73 HydrophobicContact CE3-CB 3.7Å; W60-M73 HydrophobicContact CE3-CG 4.43Å; W60-M73 VanDerWaalsContact CE3-N 3.28Å; W60-M73 HydrophobicContact CH2-CB 3.95Å; W60-M73 HydrophobicContact CH2-CE 3.49Å; W60-M73 VanDerWaalsContact CH2-CE 3.49Å; W60-M73 HydrophobicContact CH2-CG 4.44Å; W60-M73 HydrophobicContact CZ2-CB 4.25Å; W60-M73 HydrophobicContact CZ2-CE 3.3Å; W60-M73 HydrophobicContact CZ2-CG 4.27Å; W60-M73 HydrophobicContact CZ3-CB 3.67Å; W60-M73 HydrophobicContact CZ3-CE 4.37Å
61L94.7Very high86.6Confident15 Ų1557.8 Ų57.88%0.07930%0.303CS..EExtended strand (participates in β ladder)trans-111.6123.3168.8-166.466.1000107.9L41 L71 K72 I74 V114L41-L61 HydrophobicContact CD1-CD1 3.93Å; L61-L71 WeakPolarHBondContact O-CA 3.41Å; L61-K72 PolarHBondContact N-O 3.45Å; L61-K72 PolarHBondContact O-N 3.11Å; L61-I74 HydrophobicContact CB-CD1 3.79Å; L61-I74 HydrophobicContact CB-CG1 3.84Å; L61-I74 HydrophobicContact CD1-CD1 4.43Å; L61-V114 HydrophobicContact CD1-CB 4.45Å; L61-V114 HydrophobicContact CD1-CG2 4.48Å
62L94.6Very high87.1Confident0 Ų062.9 Ų62.90%033%0.325CS..EExtended strand (participates in β ladder)trans-104.2126.7171173.260.7000108.8F10 W12 V29 S46 I47 M49 P64 E70 L71F10-L62 HydrophobicContact CD1-CD2 3.46Å; F10-L62 VanDerWaalsContact CD1-CD2 3.46Å; F10-L62 HydrophobicContact CE1-CD2 3.5Å; F10-L62 VanDerWaalsContact CE1-CD2 3.5Å; W12-L62 HydrophobicContact CE3-CD2 4.13Å; W12-L62 HydrophobicContact CH2-CD1 3.97Å; W12-L62 HydrophobicContact CH2-CD2 4.43Å; W12-L62 HydrophobicContact CZ3-CD1 4.15Å; W12-L62 HydrophobicContact CZ3-CD2 3.91Å; V29-L62 HydrophobicContact CG1-CD1 3.97Å; S46-L62 WeakPolarHBondContact CA-O 3.44Å; I47-L62 HydrophobicContact CB-CB 4.18Å; I47-L62 HydrophobicContact CD1-CD2 4.14Å; I47-L62 PolarHBondContact N-O 3.11Å; I47-L62 PolarHBondContact O-N 2.76Å; M49-L62 HydrophobicContact SD-CB 3.72Å; M49-L62 HydrophobicContact SD-CD2 3.86Å; M49-L62 HydrophobicContact SD-CG 4.43Å; L62-P64 VanDerWaalsContact C-CD 3.45Å; L62-P64 WeakPolarHBondContact O-CD 3.35Å; L62-E70 WeakPolarHBondContact CA-O 3.47Å; L62-L71 HydrophobicContact CB-CD1 3.86Å; L62-L71 HydrophobicContact CD1-CB 4.36Å; L62-L71 HydrophobicContact CD1-CD1 4.32Å
63E94.8Very high88Confident55 Ų5561.7 Ų61.726%0.25732%0.322SS..EExtended strand (participates in β ladder)trans-105.780.5173.4-65.7-70.8176.500108.5S46 F65 A66 E70S46-E63 PolarHBondContact OG-OE1 3.11Å; S46-E63 PolarHBondContact OG-OE2 3.14Å; E63-F65 PolarHBondContact O-N 3.25Å; E63-F65 VanDerWaalsContact O-N 3.12Å; E63-A66 HydrophobicContact CB-CB 4.11Å; E63-A66 PolarHBondContact O-N 2.94Å; E63-E70 HydrophobicContact CB-CB 4.25Å; E63-E70 PolarHBondContact N-O 2.95Å; E63-E70 PolarHBondContact O-N 3.32Å
64P92.6Very high89.4Confident7 Ų760.9 Ų60.95%0.04531%0.309CS..THydrogen-bonded Turntrans-65.8-16.5-171.427.2-36.9000114.3W12 W40 R45 I47 L62W12-P64 HydrophobicContact CD2-CB 4.08Å; W12-P64 VanDerWaalsContact CE2-CB 3.44Å; W12-P64 HydrophobicContact CG-CB 4.39Å; W12-P64 HydrophobicContact CZ2-CB 3.7Å; W12-P64 PolarHBondContact NE1-O 3.1Å; W40-P64 HydrophobicContact CH2-CG 3.81Å; W40-P64 HydrophobicContact CZ3-CG 4.1Å; R45-P64 WeakPolarHBondContact O-CD 3.19Å; R45-P64 WeakPolarHBondContact O-CG 3.38Å; I47-P64 HydrophobicContact CD1-CG 4.13Å; I47-P64 HydrophobicContact CG1-CG 4.43Å; L62-P64 VanDerWaalsContact C-CD 3.45Å; L62-P64 WeakPolarHBondContact O-CD 3.35Å
65F90.5Very high91Very high141 Ų14154.1 Ų54.162%0.61828%0.284SS*.THydrogen-bonded Turntrans-103.2-1.9-178.7-54.8-66.3000113.8W40 R45 E63W40-F65 AromaticContact CH2-CE2 3.82Å; W40-F65 HydrophobicContact CH2-CE2 3.82Å; W40-F65 AromaticContact CH2-CZ 3.94Å; W40-F65 HydrophobicContact CH2-CZ 3.94Å; W40-F65 AromaticContact CZ3-CE2 3.83Å; W40-F65 HydrophobicContact CZ3-CE2 3.83Å; W40-F65 HydrophobicContact CZ3-CZ 4.38Å; R45-F65 WeakPolarHBondContact O-CD2 3.37Å; E63-F65 PolarHBondContact O-N 3.25Å; E63-F65 VanDerWaalsContact O-N 3.12Å
66A91.6Very high92Very high37 Ų3752.6 Ų52.631%0.30627%0.274SS..SBendtrans-65156.7166.800000109.8E63 P68 P69 E70E63-A66 HydrophobicContact CB-CB 4.11Å; E63-A66 PolarHBondContact O-N 2.94Å; A66-P68 CarbonylContact C-O 3.01Å; A66-P68 VanDerWaalsContact CB-O 3.28Å; A66-P68 WeakPolarHBondContact CB-O 3.4Å; A66-P68 CarbonylContact O-C 3.57Å; A66-P69 WeakPolarHBondContact O-CA 3.47Å; A66-P69 VanDerWaalsContact O-N 3.08Å; A66-E70 HydrophobicContact CB-CB 4.41Å
67N89.1Confident92.1Very high167 Ų16753 Ų5389%0.89327%0.274SS*.SBendtrans-126102176.7-171.518.1000110.3
68P91.5Very high92.1Very high103 Ų10357 Ų5767%0.66930%0.302SS*.SBendcis-70.3163.8-1.732.5-36.6000112.3A66 E70A66-P68 CarbonylContact C-O 3.01Å; A66-P68 VanDerWaalsContact CB-O 3.28Å; A66-P68 WeakPolarHBondContact CB-O 3.4Å; A66-P68 CarbonylContact O-C 3.57Å; P68-E70 PolarHBondContact O-N 3.19Å
69P92.3Very high91.8Very high37 Ų3756.5 Ų56.524%0.2431%0.31CS..  trans-54.2139.9170.7-23.431.7000111.5W12 T27 A66W12-P69 HydrophobicContact CH2-CB 3.52Å; W12-P69 HydrophobicContact CH2-CG 3.87Å; W12-P69 HydrophobicContact CZ2-CB 3.52Å; W12-P69 HydrophobicContact CZ2-CG 3.54Å; T27-P69 HydrophobicContact CG2-CG 3.51Å; A66-P69 WeakPolarHBondContact O-CA 3.47Å; A66-P69 VanDerWaalsContact O-N 3.08Å
70E93.3Very high91.4Very high110 Ų11058.7 Ų58.751%0.51432%0.318SS..EExtended strand (participates in β ladder)trans-113.9129.3-176.5-169.9-178.4166.600110.3L62 E63 A66 P68L62-E70 WeakPolarHBondContact CA-O 3.47Å; E63-E70 HydrophobicContact CB-CB 4.25Å; E63-E70 PolarHBondContact N-O 2.95Å; E63-E70 PolarHBondContact O-N 3.32Å; A66-E70 HydrophobicContact CB-CB 4.41Å; P68-E70 PolarHBondContact O-N 3.19Å
71L94Very high91Very high34 Ų3459.5 Ų59.518%0.17832%0.324CS..EExtended strand (participates in β ladder)trans-115.1120.3170.2-178.271.1000108.9V29 S30 C31 M49 W60 L61 L62V29-L71 HydrophobicContact CG1-CB 4.36Å; V29-L71 HydrophobicContact CG1-CD2 4.23Å; V29-L71 HydrophobicContact CG2-CB 3.86Å; V29-L71 HydrophobicContact CG2-CD2 4.41Å; S30-L71 WeakPolarHBondContact O-CD2 3.26Å; C31-L71 HydrophobicContact CB-CD2 3.85Å; M49-L71 HydrophobicContact SD-CD1 3.97Å; W60-L71 HydrophobicContact CB-CD1 4.04Å; W60-L71 HydrophobicContact CE3-CD1 4.37Å; W60-L71 HydrophobicContact CE3-CD2 4.16Å; W60-L71 HydrophobicContact CE3-CG 3.89Å; W60-L71 HydrophobicContact CZ3-CD2 4.46Å; W60-L71 HydrophobicContact CZ3-CG 4.44Å; L61-L71 WeakPolarHBondContact O-CA 3.41Å; L62-L71 HydrophobicContact CB-CD1 3.86Å; L62-L71 HydrophobicContact CD1-CB 4.36Å; L62-L71 HydrophobicContact CD1-CD1 4.32Å
72K94Very high90.5Very high111 Ų11159 Ų5948%0.48332%0.322SS..EExtended strand (participates in β ladder)trans-126.6129.3-176-179.3-179.5176.8-175.30111.5W60 L61 I74W60-K72 CarbonylContact C-O 3.5Å; W60-K72 VanDerWaalsContact CA-O 3.3Å; W60-K72 WeakPolarHBondContact CA-O 3.19Å; L61-K72 PolarHBondContact N-O 3.45Å; L61-K72 PolarHBondContact O-N 3.11Å; K72-I74 PolarHBondContact O-N 2.93Å
73M93.4Very high89.9Confident74 Ų7462 Ų6237%0.36534%0.343SS..EExtended strand (participates in β ladder)trans-71.4120168.5-166.7-169.1-66.400109.1W60W60-M73 HydrophobicContact CD2-CB 4.03Å; W60-M73 HydrophobicContact CD2-CG 4.27Å; W60-M73 HydrophobicContact CE3-CB 3.7Å; W60-M73 HydrophobicContact CE3-CG 4.43Å; W60-M73 VanDerWaalsContact CE3-N 3.28Å; W60-M73 HydrophobicContact CH2-CB 3.95Å; W60-M73 HydrophobicContact CH2-CE 3.49Å; W60-M73 VanDerWaalsContact CH2-CE 3.49Å; W60-M73 HydrophobicContact CH2-CG 4.44Å; W60-M73 HydrophobicContact CZ2-CB 4.25Å; W60-M73 HydrophobicContact CZ2-CE 3.3Å; W60-M73 HydrophobicContact CZ2-CG 4.27Å; W60-M73 HydrophobicContact CZ3-CB 3.67Å; W60-M73 HydrophobicContact CZ3-CE 4.37Å
74I94.2Very high89.1Confident17 Ų1765.1 Ų65.19%0.08736%0.355CS..EExtended strand (participates in β ladder)trans-80.9-48.1177.9-48.5179.5000109.8I59 L61 K72 L112 V114 A117I59-I74 HydrophobicContact CG2-CD1 3.88Å; I59-I74 HydrophobicContact CG2-CG1 4.43Å; I59-I74 PolarHBondContact O-N 3.49Å; L61-I74 HydrophobicContact CB-CD1 3.79Å; L61-I74 HydrophobicContact CB-CG1 3.84Å; L61-I74 HydrophobicContact CD1-CD1 4.43Å; K72-I74 PolarHBondContact O-N 2.93Å; I74-L112 HydrophobicContact CG2-CD1 4.15Å; I74-L112 HydrophobicContact CG2-CD2 4.15Å; I74-L112 HydrophobicContact CG2-CG 4.45Å; I74-V114 HydrophobicContact CD1-CB 3.8Å; I74-V114 HydrophobicContact CD1-CG1 4.02Å; I74-A117 HydrophobicContact CG2-CB 3.83Å; I74-A117 WeakPolarHBondContact O-CB 3.35Å
75I92.1Very high88.8Confident32 Ų3265.6 Ų65.616%0.16436%0.358CS..EExtended strand (participates in β ladder)trans-157.1152.5-174.3-165.1154.6000111.6R58 I59 F77 L112 L119R58-I75 WeakPolarHBondContact CA-O 3.42Å; I59-I75 HydrophobicContact CB-CG2 3.96Å; I59-I75 HydrophobicContact CD1-CG2 4.06Å; I59-I75 HydrophobicContact CG1-CG2 4.2Å; I59-I75 PolarHBondContact N-O 2.99Å; I59-I75 PolarHBondContact O-N 3.13Å; I75-F77 HydrophobicContact CB-CE2 4.5Å; I75-F77 HydrophobicContact CB-CZ 4.25Å; I75-F77 HydrophobicContact CD1-CD1 4.39Å; I75-F77 HydrophobicContact CD1-CE1 3.38Å; I75-F77 HydrophobicContact CD1-CE2 4.39Å; I75-F77 HydrophobicContact CD1-CZ 3.39Å; I75-F77 HydrophobicContact CG1-CD1 4.26Å; I75-F77 HydrophobicContact CG1-CE1 3.62Å; I75-F77 HydrophobicContact CG1-CE2 4.14Å; I75-F77 HydrophobicContact CG1-CZ 3.57Å; I75-F77 HydrophobicContact CG2-CD2 4.49Å; I75-F77 HydrophobicContact CG2-CE2 3.61Å; I75-F77 HydrophobicContact CG2-CZ 3.67Å; I75-L112 HydrophobicContact CG2-CD1 4.47Å; I75-L112 HydrophobicContact CG2-CD2 3.88Å; I75-L119 HydrophobicContact CD1-CB 4.34Å; I75-L119 HydrophobicContact CD1-CD2 4.3Å
76S92.4Very high88.8Confident59 Ų5960.5 Ų60.541%0.41334%0.339SS..EExtended strand (participates in β ladder)trans-135.9128.2176.9179.40000110V57V57-S76 CarbonylContact O-C 3.56Å; V57-S76 WeakPolarHBondContact O-CA 3.48Å
77F85.8Confident88.7Confident17 Ų1760.2 Ų60.28%0.07533%0.332CS..EExtended strand (participates in β ladder)trans-119.7109-180-48.9-75.3000110.4A56 V57 I59 I75 Y80 L97 L99 L119A56-F77 CarbonylContact C-O 3.58Å; A56-F77 WeakPolarHBondContact CA-O 3.22Å; A56-F77 WeakPolarHBondContact CB-O 3.41Å; V57-F77 HydrophobicContact CB-CB 4.45Å; V57-F77 HydrophobicContact CB-CD2 4.18Å; V57-F77 HydrophobicContact CG1-CD2 4.26Å; V57-F77 PolarHBondContact N-O 3.38Å; V57-F77 PolarHBondContact O-N 3.36Å; I59-F77 HydrophobicContact CD1-CE2 4.41Å; I75-F77 HydrophobicContact CB-CE2 4.5Å; I75-F77 HydrophobicContact CB-CZ 4.25Å; I75-F77 HydrophobicContact CD1-CD1 4.39Å; I75-F77 HydrophobicContact CD1-CE1 3.38Å; I75-F77 HydrophobicContact CD1-CE2 4.39Å; I75-F77 HydrophobicContact CD1-CZ 3.39Å; I75-F77 HydrophobicContact CG1-CD1 4.26Å; I75-F77 HydrophobicContact CG1-CE1 3.62Å; I75-F77 HydrophobicContact CG1-CE2 4.14Å; I75-F77 HydrophobicContact CG1-CZ 3.57Å; I75-F77 HydrophobicContact CG2-CD2 4.49Å; I75-F77 HydrophobicContact CG2-CE2 3.61Å; I75-F77 HydrophobicContact CG2-CZ 3.67Å; F77-Y80 HydrophobicContact CB-CD2 4.3Å; F77-Y80 HydrophobicContact CD1-CD2 4.27Å; F77-L97 HydrophobicContact CE2-CD1 4.49Å; F77-L99 HydrophobicContact CE1-CD1 4.34Å; F77-L99 HydrophobicContact CE2-CD1 4.44Å; F77-L99 HydrophobicContact CE2-CD2 4.48Å; F77-L99 HydrophobicContact CZ-CD1 4.07Å; F77-L119 HydrophobicContact CE1-CD2 3.6Å; F77-L119 HydrophobicContact CZ-CD2 3.76Å
78S86.1Confident88.7Confident84 Ų8452.4 Ų52.459%0.58729%0.291SS*.SBendtrans-82.4-29.617056.40000112.5S55 R102S55-S78 WeakPolarHBondContact O-CA 3.17Å; S78-R102 VanDerWaalsContact O-CD 3.24Å; S78-R102 WeakPolarHBondContact O-CD 3.08Å; S78-R102 PolarHBondContact O-NE 2.89Å
79S83.9Confident88.3Confident64 Ų6448.9 Ų48.945%0.44827%0.266SS..SBendtrans-93.50.5-173.356.30000114.8R101 R102S79-R101 CarbonylContact O-C 3.58Å; S79-R101 WeakPolarHBondContact O-CA 3.1Å; S79-R102 PolarHBondContact O-N 2.89Å
80Y85.8Confident88Confident47 Ų4751.7 Ų51.718%0.18427%0.272CS..EExtended strand (participates in β ladder)trans-122152.1-177.6-68.7-96.8000112.5F77 L99 S100 R101F77-Y80 HydrophobicContact CB-CD2 4.3Å; F77-Y80 HydrophobicContact CD1-CD2 4.27Å; Y80-L99 HydrophobicContact CD1-CB 3.86Å; Y80-L99 HydrophobicContact CE1-CB 4.44Å; Y80-S100 CarbonylContact C-O 3.55Å; Y80-S100 WeakPolarHBondContact CA-O 2.96Å; Y80-S100 WeakPolarHBondContact CD1-O 3.13Å; Y80-R101 HydrophobicContact CD1-CG 4Å; Y80-R101 HydrophobicContact CE1-CB 4.44Å; Y80-R101 HydrophobicContact CE1-CG 3.44Å; Y80-R101 VanDerWaalsContact CE1-CG 3.44Å; Y80-R101 HydrophobicContact CE2-CG 4.41Å; Y80-R101 PolarHBondContact OH-NE 2.8Å
81L83.6Confident87.9Confident38 Ų3849.5 Ų49.520%0.19926%0.259CS..EExtended strand (participates in β ladder)trans-101.9148159.9-61.8176000108.5L99 S100 R102 Y107L81-L99 WeakPolarHBondContact O-CA 3.41Å; L81-S100 PolarHBondContact N-O 2.92Å; L81-S100 PolarHBondContact O-N 3.25Å; L81-R102 HydrophobicContact CD2-CG 4.26Å; L81-R102 HydrophobicContact CG-CG 4.07Å; L81-Y107 HydrophobicContact CB-CE1 4.48Å
82M85.8Confident87.7Confident6 Ų650.3 Ų50.33%0.0327%0.266CS..EExtended strand (participates in β ladder)trans-117.2132.9173.3-173.5176.979.100109.2Y50 K52 V57 I59 L97 F98 L99Y50-M82 HydrophobicContact CD1-CE 4.13Å; Y50-M82 HydrophobicContact CD2-CE 3.2Å; Y50-M82 HydrophobicContact CE1-CE 4.45Å; Y50-M82 HydrophobicContact CE2-CE 3.61Å; Y50-M82 HydrophobicContact CG-CE 3.49Å; Y50-M82 VanDerWaalsContact CG-CE 3.49Å; K52-M82 PolarHBondContact NZ-O 3.38Å; V57-M82 HydrophobicContact CG1-CB 3.9Å; V57-M82 HydrophobicContact CG1-CE 4.06Å; V57-M82 HydrophobicContact CG1-SD 3.98Å; V57-M82 HydrophobicContact CG2-CB 4.01Å; I59-M82 HydrophobicContact CD1-SD 4.34Å; M82-L97 HydrophobicContact SD-CD2 3.95Å; M82-F98 WeakPolarHBondContact CA-O 3.2Å; M82-L99 HydrophobicContact CB-CD2 3.98Å; M82-L99 HydrophobicContact CG-CD2 4.01Å
83S81.1Confident87.6Confident63 Ų6347.2 Ų47.244%0.44126%0.255SS..EExtended strand (participates in β ladder)trans-105.7-37.4178.456.70000113.3F98 Y107S83-F98 PolarHBondContact N-O 3.06Å; S83-F98 VanDerWaalsContact N-O 3.14Å; S83-F98 VanDerWaalsContact OG-CB 3.25Å; S83-F98 WeakPolarHBondContact OG-CB 3.3Å; S83-Y107 VanDerWaalsContact CB-CE1 3.44Å; S83-Y107 VanDerWaalsContact OG-CD1 3.22Å; S83-Y107 WeakPolarHBondContact OG-CD1 3.4Å; S83-Y107 WeakPolarHBondContact OG-CE1 3.17Å
84F78.9Confident87.6Confident120 Ų12045.7 Ų45.753%0.52625%0.247SC..EExtended strand (participates in β ladder)trans-149.1145.9-171.1-169-110.5000111.3F98F84-F98 HydrophobicContact CB-CB 4.22Å; F84-F98 HydrophobicContact CB-CD2 4.21Å; F84-F98 HydrophobicContact CB-CG 4.39Å; F84-F98 HydrophobicContact CD1-CD2 4.16Å; F84-F98 HydrophobicContact CD1-CE2 4.31Å; F84-F98 PolarHBondContact O-N 2.81Å
85L86.1Confident87.6Confident17 Ų1744.9 Ų44.99%0.08924%0.242CC..EExtended strand (participates in β ladder)trans-127.7130.4171.9-177.4161.2000108.2L39 I48 Y50 L87 V95 L96 L97L39-L85 HydrophobicContact CD1-CD2 3.58Å; I48-L85 HydrophobicContact CD1-CD1 3.99Å; Y50-L85 HydrophobicContact CD1-CD1 4.28Å; L85-L87 HydrophobicContact CD2-CD2 3.71Å; L85-L87 HydrophobicContact CD2-CG 4.18Å; L85-V95 HydrophobicContact CD2-CB 4.41Å; L85-V95 HydrophobicContact CG-CB 4.45Å; L85-L96 CarbonylContact C-O 3.49Å; L85-L96 VanDerWaalsContact CA-O 3.27Å; L85-L96 WeakPolarHBondContact CA-O 3.31Å; L85-L97 HydrophobicContact CB-CD2 4.1Å; L85-L97 HydrophobicContact CD1-CD2 3.74Å; L85-L97 HydrophobicContact CG-CD2 3.74Å
86S89.1Confident87.8Confident33 Ų3343.5 Ų43.523%0.23124%0.235CC..EExtended strand (participates in β ladder)trans-123.5141.9173.7-173.20000111.6L96S86-L96 PolarHBondContact N-O 2.03Å; S86-L96 PolarHBondContact O-N 3.05Å
87L90.4Very high87.8Confident32 Ų3240.7 Ų40.717%0.16822%0.216CC..EExtended strand (participates in β ladder)trans-98.6156.8175.3-58.7-175.4000110.3L39 W40 L41 I48 L85 V95L39-L87 HydrophobicContact CB-CD1 3.89Å; L39-L87 HydrophobicContact CD1-CD1 4.36Å; L39-L87 HydrophobicContact CD1-CG 4.36Å; W40-L87 WeakPolarHBondContact O-CD1 3.37Å; L41-L87 HydrophobicContact CD2-CD2 3.72Å; I48-L87 HydrophobicContact CG2-CD2 4.33Å; L85-L87 HydrophobicContact CD2-CD2 3.71Å; L85-L87 HydrophobicContact CD2-CG 4.18Å; L87-V95 HydrophobicContact CD2-CB 4.27Å; L87-V95 HydrophobicContact CD2-CG1 3.41Å; L87-V95 VanDerWaalsContact CD2-CG1 3.41Å
88S88.6Confident88.2Confident2 Ų241 Ų411%0.01422%0.217CC..  trans-132.6124.7175.6171.80000111.2H42 W90 R91 D135H42-S88 PolarHBondContact CD2-O 3.19Å; S88-W90 PolarHBondContact O-N 3.5Å; S88-W90 PolarHBondContact OG-N 3.36Å; S88-W90 VanDerWaalsContact OG-N 3.07Å; S88-R91 CarbonylContact O-C 3.56Å; S88-R91 PolarHBondContact O-N 2.98Å; S88-R91 PolarHBondContact OG-N 3.42Å; S88-D135 WeakPolarHBondContact CB-O 3.32Å; S88-D135 PolarHBondContact OG-O 3.39Å
89I83.7Confident88.4Confident29 Ų2937 Ų3715%0.14919%0.19CC..THydrogen-bonded Turntrans-62.9-26.7169.955.9163.8000112.4H42 Y234H42-I89 HydrophobicContact CB-CG2 4.43Å; H42-I89 PolarHBondContact CD2-N 2.88Å; H42-I89 VanDerWaalsContact CD2-N 3.3Å; H42-I89 WeakPolarHBondContact CE1-CG2 3.4Å; H42-I89 WeakPolarHBondContact ND1-CG2 3.4Å; H42-I89 WeakPolarHBondContact NE2-CG2 3.11Å; I89-Y234 HydrophobicContact CB-CD1 4.13Å; I89-Y234 HydrophobicContact CB-CE1 3.7Å; I89-Y234 HydrophobicContact CD1-CD1 3.2Å; I89-Y234 HydrophobicContact CD1-CE1 3.7Å; I89-Y234 HydrophobicContact CD1-CG 3.76Å; I89-Y234 HydrophobicContact CG1-CD1 4.24Å; I89-Y234 HydrophobicContact CG1-CE1 4.29Å; I89-Y234 HydrophobicContact CG2-CD1 4.04Å; I89-Y234 HydrophobicContact CG2-CE1 3.3Å; I89-Y234 WeakPolarHBondContact CG2-OH 3.44Å
90W86.9Confident88.6Confident96 Ų9634 Ų3436%0.36417%0.169SC..THydrogen-bonded Turntrans-87.5-14-178.7-57.1107.3000112S88 R136 R187S88-W90 PolarHBondContact O-N 3.5Å; S88-W90 PolarHBondContact OG-N 3.36Å; S88-W90 VanDerWaalsContact OG-N 3.07Å; W90-R136 HydrophobicContact CB-CG 4.13Å; W90-R136 HydrophobicContact CG-CG 4.12Å; W90-R187 VanDerWaalsContact CH2-CZ 3.49Å; W90-R187 HydrophobicContact CZ2-CG 4.08Å
91R90.6Very high88.7Confident65 Ų6538.8 Ų38.825%0.24519%0.186CC..SBendtrans-136.463-177.2-51.4-178.966154.63.1109S88 D93 E94 R136 F137S88-R91 CarbonylContact O-C 3.56Å; S88-R91 PolarHBondContact O-N 2.98Å; S88-R91 PolarHBondContact OG-N 3.42Å; R91-D93 PolarHBondContact O-N 3.19Å; R91-D93 VanDerWaalsContact O-N 3.1Å; R91-E94 HydrophobicContact CB-CB 4.05Å; R91-E94 WeakPolarHBondContact CB-OE2 3.35Å; R91-E94 IonicContact CZ-OE2 3.29Å; R91-E94 IonicContact NE-OE2 3.84Å; R91-E94 PolarHBondContact NE-OE2 3.26Å; R91-E94 IonicContact NH2-OE1 3.79Å; R91-E94 PolarHBondContact NH2-OE1 3.02Å; R91-E94 IonicContact NH2-OE2 3Å; R91-E94 PolarHBondContact NH2-OE2 2.96Å; R91-E94 PolarHBondContact O-N 3.48Å; R91-R136 WeakPolarHBondContact CD-O 3.21Å; R91-R136 PolarHBondContact NH1-O 2.85Å; R91-R136 VanDerWaalsContact NH1-O 3.15Å; R91-F137 HydrophobicContact CB-CE2 4.19Å
92P90.1Very high88.5Confident50 Ų5041.4 Ų41.433%0.32519%0.193SC..THydrogen-bonded Turntrans-63.2-22.9-166.425.4-36.1000114.4H42 E94H42-P92 HydrophobicContact CB-CB 4.33Å; P92-E94 VanDerWaalsContact C-N 3.35Å
93D91.3Very high88.1Confident46 Ų4643.8 Ų43.825%0.24622%0.22CC..THydrogen-bonded Turntrans-946.7178.6-63.5-20.1000112.8R91 N113 V114 K115R91-D93 PolarHBondContact O-N 3.19Å; R91-D93 VanDerWaalsContact O-N 3.1Å; D93-N113 CarbonylContact O-C 3.41Å; D93-N113 WeakPolarHBondContact O-CA 3.27Å; D93-V114 WeakPolarHBondContact O-CG2 3.47Å; D93-V114 PolarHBondContact O-N 2.87Å; D93-K115 HydrophobicContact CB-CD 4.28Å; D93-K115 WeakPolarHBondContact OD1-CE 3.37Å; D93-K115 IonicContact OD1-NZ 3.27Å; D93-K115 PolarHBondContact OD1-NZ 2.88Å; D93-K115 WeakPolarHBondContact OD2-CD 3.31Å; D93-K115 WeakPolarHBondContact OD2-CE 3.23Å; D93-K115 IonicContact OD2-NZ 3.81Å; D93-K115 PolarHBondContact OD2-NZ 2.75Å
94E93.5Very high88Confident42 Ų4246.7 Ų46.720%0.19622%0.221CC..EExtended strand (participates in β ladder)trans-132.6140.9-172.1-65.2176.2126.600111.3R91 P92 I111 L112 N113 F137R91-E94 HydrophobicContact CB-CB 4.05Å; R91-E94 WeakPolarHBondContact CB-OE2 3.35Å; R91-E94 IonicContact CZ-OE2 3.29Å; R91-E94 IonicContact NE-OE2 3.84Å; R91-E94 PolarHBondContact NE-OE2 3.26Å; R91-E94 IonicContact NH2-OE1 3.79Å; R91-E94 PolarHBondContact NH2-OE1 3.02Å; R91-E94 IonicContact NH2-OE2 3Å; R91-E94 PolarHBondContact NH2-OE2 2.96Å; R91-E94 PolarHBondContact O-N 3.48Å; P92-E94 VanDerWaalsContact C-N 3.35Å; E94-I111 HydrophobicContact CB-CG2 3.82Å; E94-I111 HydrophobicContact CG-CG2 4.08Å; E94-L112 CarbonylContact C-O 3.53Å; E94-L112 VanDerWaalsContact CA-O 3.28Å; E94-L112 WeakPolarHBondContact CA-O 3.49Å; E94-N113 HydrophobicContact CG-CB 4.18Å; E94-F137 HydrophobicContact CB-CE2 4.13Å
95V94.4Very high87.9Confident0 Ų042.3 Ų42.30%020%0.204CC..EExtended strand (participates in β ladder)trans-125.9141.9177.5-56.30000110.1L41 I48 L85 L87 L97 I111 L112 V114L41-V95 HydrophobicContact CD2-CG1 4.07Å; I48-V95 HydrophobicContact CD1-CB 4.37Å; I48-V95 HydrophobicContact CD1-CG1 3.84Å; I48-V95 HydrophobicContact CD1-CG2 3.86Å; L85-V95 HydrophobicContact CD2-CB 4.41Å; L85-V95 HydrophobicContact CG-CB 4.45Å; L87-V95 HydrophobicContact CD2-CB 4.27Å; L87-V95 HydrophobicContact CD2-CG1 3.41Å; L87-V95 VanDerWaalsContact CD2-CG1 3.41Å; V95-L97 HydrophobicContact CG2-CD2 3.97Å; V95-L97 HydrophobicContact CG2-CG 4.25Å; V95-I111 WeakPolarHBondContact O-CA 3.49Å; V95-L112 HydrophobicContact CG2-CB 3.82Å; V95-L112 HydrophobicContact CG2-CD2 4.17Å; V95-L112 HydrophobicContact CG2-CG 4.31Å; V95-L112 PolarHBondContact N-O 3.44Å; V95-L112 PolarHBondContact O-N 2.72Å; V95-V114 HydrophobicContact CG1-CG1 4.05Å; V95-V114 HydrophobicContact CG2-CG1 4.29Å
96L95.2Very high87.9Confident3 Ų343 Ų432%0.01621%0.207CC..EExtended strand (participates in β ladder)trans-91.9122.3175.8178.167.6000109.4L85 S86 F98 P109 H110 I111 V122 M133 F137L85-L96 CarbonylContact C-O 3.49Å; L85-L96 VanDerWaalsContact CA-O 3.27Å; L85-L96 WeakPolarHBondContact CA-O 3.31Å; S86-L96 PolarHBondContact N-O 2.03Å; S86-L96 PolarHBondContact O-N 3.05Å; L96-F98 HydrophobicContact CD2-CE2 3.86Å; L96-F98 HydrophobicContact CG-CD2 4.43Å; L96-F98 HydrophobicContact CG-CE2 4.09Å; L96-P109 HydrophobicContact CD1-CB 3.8Å; L96-H110 CarbonylContact C-O 3.59Å; L96-H110 WeakPolarHBondContact CA-O 3.43Å; L96-I111 HydrophobicContact CD1-CG1 4.26Å; L96-V122 HydrophobicContact CD1-CG2 4.29Å; L96-M133 HydrophobicContact CD1-CE 4.31Å; L96-M133 HydrophobicContact CD2-CB 3.89Å; L96-M133 HydrophobicContact CD2-CE 4.14Å; L96-M133 HydrophobicContact CD2-CG 3.91Å; L96-F137 HydrophobicContact CB-CD1 3.5Å; L96-F137 VanDerWaalsContact CB-CD1 3.5Å; L96-F137 HydrophobicContact CB-CD2 4.23Å; L96-F137 HydrophobicContact CB-CE1 3.49Å; L96-F137 VanDerWaalsContact CB-CE1 3.49Å; L96-F137 HydrophobicContact CB-CE2 4.24Å; L96-F137 HydrophobicContact CB-CG 3.87Å; L96-F137 HydrophobicContact CB-CZ 3.87Å; L96-F137 HydrophobicContact CD1-CB 4.3Å; L96-F137 HydrophobicContact CD1-CG 4.46Å; L96-F137 HydrophobicContact CD2-CB 4.44Å; L96-F137 HydrophobicContact CD2-CD1 3.8Å; L96-F137 HydrophobicContact CD2-CE1 4.4Å; L96-F137 HydrophobicContact CD2-CG 4.35Å; L96-F137 HydrophobicContact CG-CD1 4.18Å; L96-F137 HydrophobicContact CG-CG 4.47Å
97L94.1Very high88Confident0 Ų043.9 Ų43.90%021%0.206CC..EExtended strand (participates in β ladder)trans-113.5132.5179.3-53.9179.1000109.8I59 F77 M82 L85 V95 L99 P109 H110 L112 L119I59-L97 HydrophobicContact CD1-CD1 3.51Å; I59-L97 HydrophobicContact CD1-CD2 3.91Å; I59-L97 HydrophobicContact CD1-CG 4.37Å; F77-L97 HydrophobicContact CE2-CD1 4.49Å; M82-L97 HydrophobicContact SD-CD2 3.95Å; L85-L97 HydrophobicContact CB-CD2 4.1Å; L85-L97 HydrophobicContact CD1-CD2 3.74Å; L85-L97 HydrophobicContact CG-CD2 3.74Å; V95-L97 HydrophobicContact CG2-CD2 3.97Å; V95-L97 HydrophobicContact CG2-CG 4.25Å; L97-L99 HydrophobicContact CB-CD1 4.47Å; L97-L99 HydrophobicContact CB-CD2 4.09Å; L97-L99 HydrophobicContact CB-CG 4.03Å; L97-P109 CarbonylContact O-C 3.58Å; L97-P109 WeakPolarHBondContact O-CA 3.09Å; L97-H110 PolarHBondContact N-O 3.12Å; L97-H110 PolarHBondContact O-N 3.03Å; L97-L112 HydrophobicContact CD1-CB 3.84Å; L97-L112 HydrophobicContact CD1-CD2 4Å; L97-L112 HydrophobicContact CG-CB 4.36Å; L97-L119 HydrophobicContact CD1-CD1 4.15Å
98F92.8Very high88.2Confident23 Ų2343.3 Ų43.310%0.10120%0.202CC..EExtended strand (participates in β ladder)trans-95.1109.7168-81.4-111.4000109.2M82 S83 F84 L96 Y107 P109 L131 M133M82-F98 WeakPolarHBondContact CA-O 3.2Å; S83-F98 PolarHBondContact N-O 3.06Å; S83-F98 VanDerWaalsContact N-O 3.14Å; S83-F98 VanDerWaalsContact OG-CB 3.25Å; S83-F98 WeakPolarHBondContact OG-CB 3.3Å; F84-F98 HydrophobicContact CB-CB 4.22Å; F84-F98 HydrophobicContact CB-CD2 4.21Å; F84-F98 HydrophobicContact CB-CG 4.39Å; F84-F98 HydrophobicContact CD1-CD2 4.16Å; F84-F98 HydrophobicContact CD1-CE2 4.31Å; F84-F98 PolarHBondContact O-N 2.81Å; L96-F98 HydrophobicContact CD2-CE2 3.86Å; L96-F98 HydrophobicContact CG-CD2 4.43Å; L96-F98 HydrophobicContact CG-CE2 4.09Å; F98-Y107 HydrophobicContact CB-CD1 4.36Å; F98-P109 HydrophobicContact CE2-CB 4.43Å; F98-P109 HydrophobicContact CZ-CB 4.33Å; F98-L131 HydrophobicContact CE1-CB 3.92Å; F98-L131 HydrophobicContact CE1-CD1 3.89Å; F98-L131 HydrophobicContact CE1-CG 4.28Å; F98-L131 HydrophobicContact CZ-CB 4.27Å; F98-M133 HydrophobicContact CE2-CG 4.29Å; F98-M133 HydrophobicContact CZ-CG 3.84Å
99L91.3Very high88.5Confident2 Ų243.2 Ų43.21%0.0120%0.201CC..EExtended strand (participates in β ladder)trans-115132.5-174.3-57.6179.9000110.6F77 Y80 L81 M82 L97 E108 H110 L119F77-L99 HydrophobicContact CE1-CD1 4.34Å; F77-L99 HydrophobicContact CE2-CD1 4.44Å; F77-L99 HydrophobicContact CE2-CD2 4.48Å; F77-L99 HydrophobicContact CZ-CD1 4.07Å; Y80-L99 HydrophobicContact CD1-CB 3.86Å; Y80-L99 HydrophobicContact CE1-CB 4.44Å; L81-L99 WeakPolarHBondContact O-CA 3.41Å; M82-L99 HydrophobicContact CB-CD2 3.98Å; M82-L99 HydrophobicContact CG-CD2 4.01Å; L97-L99 HydrophobicContact CB-CD1 4.47Å; L97-L99 HydrophobicContact CB-CD2 4.09Å; L97-L99 HydrophobicContact CB-CG 4.03Å; L99-E108 PolarHBondContact N-O 2.88Å; L99-E108 PolarHBondContact O-N 2.96Å; L99-H110 HydrophobicContact CD1-CB 4.16Å; L99-L119 HydrophobicContact CD1-CD2 4.01Å
100S88.1Confident89Confident1 Ų142.6 Ų42.61%0.00720%0.198CC..EExtended strand (participates in β ladder)trans-117.7139167.8-178.70000109.1Y80 L81 R104 I106Y80-S100 CarbonylContact C-O 3.55Å; Y80-S100 WeakPolarHBondContact CA-O 2.96Å; Y80-S100 WeakPolarHBondContact CD1-O 3.13Å; L81-S100 PolarHBondContact N-O 2.92Å; L81-S100 PolarHBondContact O-N 3.25Å; S100-R104 PolarHBondContact OG-O 2.8Å; S100-I106 WeakPolarHBondContact CB-O 3.25Å; S100-I106 PolarHBondContact OG-O 3.23Å
101R86.6Confident89.5Confident147 Ų14738.6 Ų38.656%0.55518%0.184SC*.EExtended strand (participates in β ladder)trans-63.9139.2168.7-74.1-175.9174.4179.7-1108.8S79 Y80 G103 R104S79-R101 CarbonylContact O-C 3.58Å; S79-R101 WeakPolarHBondContact O-CA 3.1Å; Y80-R101 HydrophobicContact CD1-CG 4Å; Y80-R101 HydrophobicContact CE1-CB 4.44Å; Y80-R101 HydrophobicContact CE1-CG 3.44Å; Y80-R101 VanDerWaalsContact CE1-CG 3.44Å; Y80-R101 HydrophobicContact CE2-CG 4.41Å; Y80-R101 PolarHBondContact OH-NE 2.8Å; R101-G103 PolarHBondContact O-N 2.81Å; R101-R104 HydrophobicContact CB-CB 4.4Å; R101-R104 HydrophobicContact CB-CG 4.41Å; R101-R104 WeakPolarHBondContact O-CA 3.4Å; R101-R104 WeakPolarHBondContact O-CB 3.12Å; R101-R104 PolarHBondContact O-N 3.45Å
102R79.4Confident89.7Confident93 Ų9335.5 Ų35.535%0.35117%0.172SC..THydrogen-bonded Turntrans-53.1133175-73.3-176.8-175.9-93.4-0.8110.1Y54 S55 S78 S79 L81 R104Y54-R102 PolarHBondContact O-NH1 3.04Å; Y54-R102 PolarHBondContact O-NH2 2.96Å; S55-R102 VanDerWaalsContact C-NH2 3.32Å; S55-R102 PolarHBondContact O-NH2 2.95Å; S78-R102 VanDerWaalsContact O-CD 3.24Å; S78-R102 WeakPolarHBondContact O-CD 3.08Å; S78-R102 PolarHBondContact O-NE 2.89Å; S79-R102 PolarHBondContact O-N 2.89Å; L81-R102 HydrophobicContact CD2-CG 4.26Å; L81-R102 HydrophobicContact CG-CG 4.07Å; R102-R104 VanDerWaalsContact C-N 3.26Å; R102-R104 PolarHBondContact O-N 2.9Å
103G77.1Confident89.9Confident56 Ų5634.5 Ų34.558%0.57716%0.164SC*.THydrogen-bonded Turntrans81.7-6.8-174.300000115.2R101R101-G103 PolarHBondContact O-N 2.81Å
104R79.6Confident90Very high124 Ų12432.6 Ų32.647%0.46815%0.154SC..  trans-97.4149.5165.5-76.6-171.6149.9-151.3-8.3111S100 R101 R102S100-R104 PolarHBondContact OG-O 2.8Å; R101-R104 HydrophobicContact CB-CB 4.4Å; R101-R104 HydrophobicContact CB-CG 4.41Å; R101-R104 WeakPolarHBondContact O-CA 3.4Å; R101-R104 WeakPolarHBondContact O-CB 3.12Å; R101-R104 PolarHBondContact O-N 3.45Å; R102-R104 VanDerWaalsContact C-N 3.26Å; R102-R104 PolarHBondContact O-N 2.9Å
105V76.6Confident89.8Confident27 Ų2736.3 Ų36.316%0.16417%0.17CC..  trans-97.3-5.9-176.2170.20000112.3R485 L489V105-R485 WeakPolarHBondContact CG1-O 3.42Å; V105-R485 HydrophobicContact CG2-CB 3.5Å; V105-R485 VanDerWaalsContact CG2-CB 3.5Å; V105-R485 WeakPolarHBondContact CG2-O 3.28Å; V105-L489 HydrophobicContact CG1-CD1 4.02Å; V105-L489 HydrophobicContact CG1-CG 3.88Å
106I87.2Confident89.7Confident32 Ų3240.8 Ų40.816%0.16420%0.197CC..  trans-110.8118.3-168.3-61.7156.7000109.4S100 N125 E126 L489S100-I106 WeakPolarHBondContact CB-O 3.25Å; S100-I106 PolarHBondContact OG-O 3.23Å; I106-N125 HydrophobicContact CG2-CB 3.58Å; I106-N125 WeakPolarHBondContact CG2-ND2 3.35Å; I106-N125 VanDerWaalsContact CG2-O 3.22Å; I106-N125 WeakPolarHBondContact CG2-O 3.41Å; I106-E126 WeakPolarHBondContact CD1-O 3.34Å; I106-L489 HydrophobicContact CG1-CD1 3.97Å
107Y90.7Very high89.6Confident51 Ų5142.6 Ų42.620%0.221%0.212CC..  trans-86.1135.4174.7-70.2-90.8000111.1L81 S83 F98 N125L81-Y107 HydrophobicContact CB-CE1 4.48Å; S83-Y107 VanDerWaalsContact CB-CE1 3.44Å; S83-Y107 VanDerWaalsContact OG-CD1 3.22Å; S83-Y107 WeakPolarHBondContact OG-CD1 3.4Å; S83-Y107 WeakPolarHBondContact OG-CE1 3.17Å; F98-Y107 HydrophobicContact CB-CD1 4.36Å; Y107-N125 WeakPolarHBondContact O-CB 3.47Å; Y107-N125 PolarHBondContact O-ND2 2.86Å; Y107-N125 VanDerWaalsContact O-ND2 3.08Å
108E93.6Very high89.7Confident20 Ų2048.4 Ų48.49%0.09324%0.237CC..EExtended strand (participates in β ladder)trans-115.5132178.3-65.8-174.9165.600109.8L99 H110 R121 K124 N125L99-E108 PolarHBondContact N-O 2.88Å; L99-E108 PolarHBondContact O-N 2.96Å; E108-H110 PolarHBondContact O-ND1 2.79Å; E108-H110 IonicContact OE2-CE1 3.73Å; E108-R121 IonicContact OE1-NH1 2.71Å; E108-R121 WeakPolarHBondContact OE2-CD 3.27Å; E108-R121 IonicContact OE2-NH1 2.59Å; E108-R121 PolarHBondContact OE2-NH1 2.95Å; E108-K124 WeakPolarHBondContact OE1-CG 3.33Å; E108-N125 HydrophobicContact CG-CB 4.19Å
109P95.6Very high89.8Confident0 Ų050 Ų500%025%0.247CC..EExtended strand (participates in β ladder)trans-75.4130.5177.728.1-31.8000110.7L96 L97 F98 V122 F123 L131 M133L96-P109 HydrophobicContact CD1-CB 3.8Å; L97-P109 CarbonylContact O-C 3.58Å; L97-P109 WeakPolarHBondContact O-CA 3.09Å; F98-P109 HydrophobicContact CE2-CB 4.43Å; F98-P109 HydrophobicContact CZ-CB 4.33Å; P109-V122 HydrophobicContact CB-CB 4.26Å; P109-V122 HydrophobicContact CG-CB 4.16Å; P109-V122 PolarHBondContact O-N 2.89Å; P109-F123 WeakPolarHBondContact CD-O 3.47Å; P109-F123 HydrophobicContact CG-CB 3.75Å; P109-L131 VanDerWaalsContact CD-CD1 3.48Å; P109-L131 HydrophobicContact CG-CD1 3.94Å; P109-M133 HydrophobicContact CB-CE 4.28Å; P109-M133 HydrophobicContact CB-SD 4.49Å; P109-M133 HydrophobicContact CG-SD 4.47Å
110H95.3Very high90Very high16 Ų1654.2 Ų54.27%0.07427%0.266CS..EExtended strand (participates in β ladder)trans-128.8143.3177.1-6772.5000110.2L96 L97 L99 E108 L119 E120L96-H110 CarbonylContact C-O 3.59Å; L96-H110 WeakPolarHBondContact CA-O 3.43Å; L97-H110 PolarHBondContact N-O 3.12Å; L97-H110 PolarHBondContact O-N 3.03Å; L99-H110 HydrophobicContact CD1-CB 4.16Å; E108-H110 PolarHBondContact O-ND1 2.79Å; E108-H110 IonicContact OE2-CE1 3.73Å; H110-L119 HydrophobicContact CB-CD1 3.74Å; H110-L119 HydrophobicContact CB-CG 4.17Å; H110-E120 CarbonylContact C-O 3.54Å; H110-E120 WeakPolarHBondContact CA-O 3.05Å
111I95.9Very high90.2Very high12 Ų1259.1 Ų59.16%0.06229%0.285CS..EExtended strand (participates in β ladder)trans-101122.9172.5-66.9163.3000108E94 V95 L96 L119 E120 V122 F137E94-I111 HydrophobicContact CB-CG2 3.82Å; E94-I111 HydrophobicContact CG-CG2 4.08Å; V95-I111 WeakPolarHBondContact O-CA 3.49Å; L96-I111 HydrophobicContact CD1-CG1 4.26Å; I111-L119 CarbonylContact O-C 3.51Å; I111-L119 WeakPolarHBondContact O-CA 3.31Å; I111-E120 PolarHBondContact N-O 3.32Å; I111-E120 PolarHBondContact O-N 2.94Å; I111-V122 HydrophobicContact CB-CG2 4.39Å; I111-V122 HydrophobicContact CD1-CG2 3.39Å; I111-V122 HydrophobicContact CG1-CG2 3.44Å; I111-V122 VanDerWaalsContact CG1-CG2 3.44Å; I111-F137 HydrophobicContact CD1-CB 3.81Å; I111-F137 HydrophobicContact CD1-CD2 4Å; I111-F137 HydrophobicContact CD1-CG 4.4Å; I111-F137 HydrophobicContact CG1-CB 4.09Å; I111-F137 HydrophobicContact CG1-CD2 3.82Å; I111-F137 HydrophobicContact CG1-CG 4.31Å; I111-F137 HydrophobicContact CG2-CD2 4.43Å
112L95.2Very high90.6Very high0 Ų052.8 Ų52.80%026%0.262CS..EExtended strand (participates in β ladder)trans-102121171.1173.464.8000108.7I59 I74 I75 E94 V95 L97 K118 L119I59-L112 HydrophobicContact CD1-CD2 3.82Å; I59-L112 HydrophobicContact CG2-CD2 4.3Å; I74-L112 HydrophobicContact CG2-CD1 4.15Å; I74-L112 HydrophobicContact CG2-CD2 4.15Å; I74-L112 HydrophobicContact CG2-CG 4.45Å; I75-L112 HydrophobicContact CG2-CD1 4.47Å; I75-L112 HydrophobicContact CG2-CD2 3.88Å; E94-L112 CarbonylContact C-O 3.53Å; E94-L112 VanDerWaalsContact CA-O 3.28Å; E94-L112 WeakPolarHBondContact CA-O 3.49Å; V95-L112 HydrophobicContact CG2-CB 3.82Å; V95-L112 HydrophobicContact CG2-CD2 4.17Å; V95-L112 HydrophobicContact CG2-CG 4.31Å; V95-L112 PolarHBondContact N-O 3.44Å; V95-L112 PolarHBondContact O-N 2.72Å; L97-L112 HydrophobicContact CD1-CB 3.84Å; L97-L112 HydrophobicContact CD1-CD2 4Å; L97-L112 HydrophobicContact CG-CB 4.36Å; L112-K118 WeakPolarHBondContact CA-O 3.27Å; L112-L119 HydrophobicContact CB-CD1 3.81Å; L112-L119 HydrophobicContact CD1-CB 4.47Å; L112-L119 HydrophobicContact CD1-CD1 4.34Å
113N95.1Very high91.3Very high30 Ų3049 Ų4916%0.1625%0.249CC..EExtended strand (participates in β ladder)trans-82.8115.1165.9-178.4-73.5000109.2D93 E94 K115 T116 A117 K118D93-N113 CarbonylContact O-C 3.41Å; D93-N113 WeakPolarHBondContact O-CA 3.27Å; E94-N113 HydrophobicContact CG-CB 4.18Å; N113-K115 VanDerWaalsContact C-N 3.29Å; N113-K115 PolarHBondContact O-N 2.83Å; N113-K115 PolarHBondContact OD1-N 2.98Å; N113-T116 WeakPolarHBondContact CB-OG1 3.31Å; N113-T116 PolarHBondContact O-N 3.43Å; N113-T116 WeakPolarHBondContact OD1-CB 3.24Å; N113-T116 WeakPolarHBondContact OD1-CG2 3.45Å; N113-T116 PolarHBondContact OD1-N 3.4Å; N113-T116 PolarHBondContact OD1-OG1 3.04Å; N113-A117 VanDerWaalsContact O-CA 3.28Å; N113-A117 WeakPolarHBondContact O-CA 3.45Å; N113-A117 PolarHBondContact O-N 3.32Å; N113-K118 HydrophobicContact CB-CB 4.45Å; N113-K118 PolarHBondContact N-O 2.83Å
114V92.4Very high92.1Very high6 Ų651.1 Ų51.14%0.03624%0.242CC..THydrogen-bonded Turntrans-70.2-25.4-170.4-58.40000113.1L41 I48 L61 I74 D93 V95L41-V114 HydrophobicContact CD1-CG1 4.44Å; L41-V114 HydrophobicContact CD1-CG2 3.75Å; I48-V114 HydrophobicContact CD1-CG1 4.11Å; L61-V114 HydrophobicContact CD1-CB 4.45Å; L61-V114 HydrophobicContact CD1-CG2 4.48Å; I74-V114 HydrophobicContact CD1-CB 3.8Å; I74-V114 HydrophobicContact CD1-CG1 4.02Å; D93-V114 WeakPolarHBondContact O-CG2 3.47Å; D93-V114 PolarHBondContact O-N 2.87Å; V95-V114 HydrophobicContact CG1-CG1 4.05Å; V95-V114 HydrophobicContact CG2-CG1 4.29Å
115K88.8Confident92.7Very high120 Ų12045.4 Ų45.452%0.52222%0.221SC..THydrogen-bonded Turntrans-80.8-40.1-179.7-66.3-177.5177.11640112.4D93 N113D93-K115 HydrophobicContact CB-CD 4.28Å; D93-K115 WeakPolarHBondContact OD1-CE 3.37Å; D93-K115 IonicContact OD1-NZ 3.27Å; D93-K115 PolarHBondContact OD1-NZ 2.88Å; D93-K115 WeakPolarHBondContact OD2-CD 3.31Å; D93-K115 WeakPolarHBondContact OD2-CE 3.23Å; D93-K115 IonicContact OD2-NZ 3.81Å; D93-K115 PolarHBondContact OD2-NZ 2.75Å; N113-K115 VanDerWaalsContact C-N 3.29Å; N113-K115 PolarHBondContact O-N 2.83Å; N113-K115 PolarHBondContact OD1-N 2.98Å
116T93.4Very high93.2Very high94 Ų9450.1 Ų50.158%0.57724%0.241SC*.THydrogen-bonded Turntrans-99-9.5-175.462.20000113.6N113 K118N113-T116 WeakPolarHBondContact CB-OG1 3.31Å; N113-T116 PolarHBondContact O-N 3.43Å; N113-T116 WeakPolarHBondContact OD1-CB 3.24Å; N113-T116 WeakPolarHBondContact OD1-CG2 3.45Å; N113-T116 PolarHBondContact OD1-N 3.4Å; N113-T116 PolarHBondContact OD1-OG1 3.04Å; T116-K118 PolarHBondContact O-N 3.13Å; T116-K118 VanDerWaalsContact O-N 3.14Å; T116-K118 WeakPolarHBondContact OG1-CB 3.48Å; T116-K118 PolarHBondContact OG1-N 3.43Å
117A93Very high93.2Very high41 Ų4152.7 Ų52.734%0.33926%0.255SS..  trans57.415.7-169.700000114.3I74 N113 L119I74-A117 HydrophobicContact CG2-CB 3.83Å; I74-A117 WeakPolarHBondContact O-CB 3.35Å; N113-A117 VanDerWaalsContact O-CA 3.28Å; N113-A117 WeakPolarHBondContact O-CA 3.45Å; N113-A117 PolarHBondContact O-N 3.32Å; A117-L119 PolarHBondContact O-N 3.12Å
118K95.8Very high93.4Very high121 Ų12151.1 Ų51.153%0.52625%0.249SC..  trans-72.6125.5177.3-166.7-171.8-166.9-1680109.7L112 N113 T116 E120L112-K118 WeakPolarHBondContact CA-O 3.27Å; N113-K118 HydrophobicContact CB-CB 4.45Å; N113-K118 PolarHBondContact N-O 2.83Å; T116-K118 PolarHBondContact O-N 3.13Å; T116-K118 VanDerWaalsContact O-N 3.14Å; T116-K118 WeakPolarHBondContact OG1-CB 3.48Å; T116-K118 PolarHBondContact OG1-N 3.43Å; K118-E120 HydrophobicContact CD-CG 4.25Å; K118-E120 WeakPolarHBondContact CE-OE1 3.44Å; K118-E120 HydrophobicContact CG-CG 4.27Å; K118-E120 IonicContact NZ-OE1 2.78Å; K118-E120 PolarHBondContact NZ-OE1 3.24Å
119L94.7Very high93.2Very high57 Ų5752.4 Ų52.430%0.29826%0.261SS..EExtended strand (participates in β ladder)trans-111.9124.1176-173.174.7000110.3I75 F77 L97 L99 H110 I111 L112 A117I75-L119 HydrophobicContact CD1-CB 4.34Å; I75-L119 HydrophobicContact CD1-CD2 4.3Å; F77-L119 HydrophobicContact CE1-CD2 3.6Å; F77-L119 HydrophobicContact CZ-CD2 3.76Å; L97-L119 HydrophobicContact CD1-CD1 4.15Å; L99-L119 HydrophobicContact CD1-CD2 4.01Å; H110-L119 HydrophobicContact CB-CD1 3.74Å; H110-L119 HydrophobicContact CB-CG 4.17Å; I111-L119 CarbonylContact O-C 3.51Å; I111-L119 WeakPolarHBondContact O-CA 3.31Å; L112-L119 HydrophobicContact CB-CD1 3.81Å; L112-L119 HydrophobicContact CD1-CB 4.47Å; L112-L119 HydrophobicContact CD1-CD1 4.34Å; A117-L119 PolarHBondContact O-N 3.12Å
120E95.1Very high93Very high90 Ų9055 Ų5542%0.42128%0.279SS..EExtended strand (participates in β ladder)trans-125.8133.2-179.4-63.5-171154.800111.3H110 I111 K118H110-E120 CarbonylContact C-O 3.54Å; H110-E120 WeakPolarHBondContact CA-O 3.05Å; I111-E120 PolarHBondContact N-O 3.32Å; I111-E120 PolarHBondContact O-N 2.94Å; K118-E120 HydrophobicContact CD-CG 4.25Å; K118-E120 WeakPolarHBondContact CE-OE1 3.44Å; K118-E120 HydrophobicContact CG-CG 4.27Å; K118-E120 IonicContact NZ-OE1 2.78Å; K118-E120 PolarHBondContact NZ-OE1 3.24Å
121R94.2Very high93Very high104 Ų10455 Ų5539%0.39228%0.279SS..EExtended strand (participates in β ladder)trans-76.4130174.6-173.8174.161-169.4-4.9110.5E108 F123 L162E108-R121 IonicContact OE1-NH1 2.71Å; E108-R121 WeakPolarHBondContact OE2-CD 3.27Å; E108-R121 IonicContact OE2-NH1 2.59Å; E108-R121 PolarHBondContact OE2-NH1 2.95Å; R121-F123 WeakPolarHBondContact CG-O 3.31Å; R121-L162 VanDerWaalsContact O-CD2 3.22Å; R121-L162 WeakPolarHBondContact O-CD2 3.4Å
122V94.2Very high92.9Very high14 Ų1454.9 Ų54.99%0.08528%0.279CS..SBendtrans-86-39.1177.2-174.70000111.7L96 P109 I111 M133 L162L96-V122 HydrophobicContact CD1-CG2 4.29Å; P109-V122 HydrophobicContact CB-CB 4.26Å; P109-V122 HydrophobicContact CG-CB 4.16Å; P109-V122 PolarHBondContact O-N 2.89Å; I111-V122 HydrophobicContact CB-CG2 4.39Å; I111-V122 HydrophobicContact CD1-CG2 3.39Å; I111-V122 HydrophobicContact CG1-CG2 3.44Å; I111-V122 VanDerWaalsContact CG1-CG2 3.44Å; V122-M133 HydrophobicContact CG1-CE 4Å; V122-L162 WeakPolarHBondContact O-CD2 3.34Å
123F94.3Very high92.9Very high15 Ų1555.7 Ų55.77%0.06628%0.283CS..  trans-150.4138-177.7174.7-116.1000110.3P109 R121 N125 F128 L131 L139 Y164 F166P109-F123 WeakPolarHBondContact CD-O 3.47Å; P109-F123 HydrophobicContact CG-CB 3.75Å; R121-F123 WeakPolarHBondContact CG-O 3.31Å; F123-N125 HydrophobicContact CD1-CB 4.03Å; F123-N125 HydrophobicContact CE1-CB 3.79Å; F123-F128 HydrophobicContact CE1-CD2 4.12Å; F123-F128 HydrophobicContact CZ-CD2 4.14Å; F123-F128 HydrophobicContact CZ-CE2 4.13Å; F123-L131 HydrophobicContact CD1-CD1 4.08Å; F123-L131 HydrophobicContact CD1-CD2 4.09Å; F123-L131 HydrophobicContact CE1-CD2 3.88Å; F123-L139 HydrophobicContact CB-CD2 4.33Å; F123-L139 HydrophobicContact CD1-CD2 3.9Å; F123-L139 HydrophobicContact CD2-CD2 4.03Å; F123-L139 HydrophobicContact CE1-CD2 4.2Å; F123-L139 HydrophobicContact CE2-CD2 4.35Å; F123-L139 HydrophobicContact CG-CD2 3.82Å; F123-L139 HydrophobicContact CZ-CD2 4.42Å; F123-Y164 AromaticContact CD2-CD2 3.71Å; F123-Y164 HydrophobicContact CD2-CD2 3.71Å; F123-Y164 HydrophobicContact CD2-CE2 4.06Å; F123-Y164 HydrophobicContact CE2-CD2 4.19Å; F123-F166 HydrophobicContact CE2-CE2 4.34Å; F123-F166 AromaticContact CE2-CZ 3.65Å; F123-F166 HydrophobicContact CE2-CZ 3.65Å; F123-F166 HydrophobicContact CZ-CE1 4.47Å; F123-F166 HydrophobicContact CZ-CE2 4.26Å; F123-F166 AromaticContact CZ-CZ 3.55Å; F123-F166 HydrophobicContact CZ-CZ 3.55Å
124K93Very high92.7Very high99 Ų9954.5 Ų54.543%0.4328%0.276SS..  trans-90.8100.6171.5-175.3-168.8176.1-148.60107.9E108 E126E108-K124 WeakPolarHBondContact OE1-CG 3.33Å; K124-E126 WeakPolarHBondContact CE-OE1 3.16Å; K124-E126 IonicContact NZ-OE1 3.27Å; K124-E126 PolarHBondContact NZ-OE1 3.24Å
125N92.6Very high92.5Very high4 Ų456.1 Ų56.12%0.02128%0.284CS..  trans-79127.5177-172.77.8000110I106 Y107 E108 F123 N127 F128 L131I106-N125 HydrophobicContact CG2-CB 3.58Å; I106-N125 WeakPolarHBondContact CG2-ND2 3.35Å; I106-N125 VanDerWaalsContact CG2-O 3.22Å; I106-N125 WeakPolarHBondContact CG2-O 3.41Å; Y107-N125 WeakPolarHBondContact O-CB 3.47Å; Y107-N125 PolarHBondContact O-ND2 2.86Å; Y107-N125 VanDerWaalsContact O-ND2 3.08Å; E108-N125 HydrophobicContact CG-CB 4.19Å; F123-N125 HydrophobicContact CD1-CB 4.03Å; F123-N125 HydrophobicContact CE1-CB 3.79Å; N125-N127 PolarHBondContact OD1-N 3.47Å; N125-F128 PolarHBondContact ND2-O 2.95Å; N125-F128 WeakPolarHBondContact OD1-CB 3.37Å; N125-F128 PolarHBondContact OD1-N 2.93Å; N125-L131 HydrophobicContact CB-CD1 4.23Å
126E86.6Confident92.6Very high127 Ų12754.6 Ų54.659%0.59328%0.276SS*.SBendtrans-108.8-26.6-178.7-60.8-164.4155.400113I106 K124I106-E126 WeakPolarHBondContact CD1-O 3.34Å; K124-E126 WeakPolarHBondContact CE-OE1 3.16Å; K124-E126 IonicContact NZ-OE1 3.27Å; K124-E126 PolarHBondContact NZ-OE1 3.24Å
127N88.7Confident92.5Very high85 Ų8550.3 Ų50.346%0.45525%0.249SC..SBendtrans-163.22.6-171.865.5-18000115.5N125N125-N127 PolarHBondContact OD1-N 3.47Å
128F93.1Very high92.5Very high18 Ų1853 Ų538%0.07925%0.25CS..  trans-83.5133.2-179.5-62.3-67.7000110.6F123 N125 L131 V142 A143 N144 Y154 F166F123-F128 HydrophobicContact CE1-CD2 4.12Å; F123-F128 HydrophobicContact CZ-CD2 4.14Å; F123-F128 HydrophobicContact CZ-CE2 4.13Å; N125-F128 PolarHBondContact ND2-O 2.95Å; N125-F128 WeakPolarHBondContact OD1-CB 3.37Å; N125-F128 PolarHBondContact OD1-N 2.93Å; F128-L131 HydrophobicContact CB-CD2 3.87Å; F128-L131 HydrophobicContact CD2-CD2 4.47Å; F128-V142 HydrophobicContact CB-CB 4.11Å; F128-V142 HydrophobicContact CD1-CB 3.66Å; F128-V142 HydrophobicContact CD1-CG2 3.56Å; F128-V142 HydrophobicContact CD2-CB 3.92Å; F128-V142 HydrophobicContact CD2-CG1 4.05Å; F128-V142 HydrophobicContact CD2-CG2 4.06Å; F128-V142 HydrophobicContact CE1-CB 4Å; F128-V142 HydrophobicContact CE1-CG2 3.35Å; F128-V142 HydrophobicContact CE2-CB 4.24Å; F128-V142 HydrophobicContact CE2-CG1 4.37Å; F128-V142 HydrophobicContact CE2-CG2 3.86Å; F128-V142 HydrophobicContact CG-CB 3.62Å; F128-V142 HydrophobicContact CG-CG1 4.19Å; F128-V142 HydrophobicContact CG-CG2 3.92Å; F128-V142 HydrophobicContact CZ-CB 4.28Å; F128-V142 HydrophobicContact CZ-CG2 3.51Å; F128-A143 CarbonylContact C-O 3.52Å; F128-A143 VanDerWaalsContact CA-O 3.31Å; F128-A143 WeakPolarHBondContact CA-O 3.28Å; F128-A143 WeakPolarHBondContact CB-O 3.09Å; F128-N144 HydrophobicContact CD1-CB 4.31Å; F128-Y154 HydrophobicContact CE1-CD2 4.14Å; F128-Y154 HydrophobicContact CE1-CE2 4.42Å; F128-F166 HydrophobicContact CE2-CD2 4.18Å; F128-F166 HydrophobicContact CE2-CE1 4.14Å; F128-F166 AromaticContact CE2-CE2 3.76Å; F128-F166 HydrophobicContact CE2-CE2 3.76Å; F128-F166 AromaticContact CE2-CZ 3.74Å; F128-F166 HydrophobicContact CE2-CZ 3.74Å; F128-F166 HydrophobicContact CZ-CD1 4.31Å; F128-F166 AromaticContact CZ-CD2 3.95Å; F128-F166 HydrophobicContact CZ-CD2 3.95Å; F128-F166 HydrophobicContact CZ-CE1 4.37Å; F128-F166 HydrophobicContact CZ-CE2 4.02Å; F128-F166 HydrophobicContact CZ-CG 4.09Å; F128-F166 HydrophobicContact CZ-CZ 4.23Å
129S90.4Very high92.4Very high48 Ų4847.6 Ų47.634%0.33623%0.227SC..SBendtrans-76.3-27.3177.858.60000112.4A143S129-A143 PolarHBondContact N-O 3.18Å; S129-A143 PolarHBondContact OG-O 3.07Å; S129-A143 VanDerWaalsContact OG-O 3.14Å
130S91.8Very high92.4Very high54 Ų5445.6 Ų45.638%0.37822%0.216SC..EExtended strand (participates in β ladder)trans-140.4144.5178.8-176.40000111.2V142 A143S130-V142 WeakPolarHBondContact O-CA 3.33Å; S130-A143 PolarHBondContact N-O 2.91Å; S130-A143 PolarHBondContact O-N 2.88Å
131L94.7Very high92.4Very high17 Ų1741.4 Ų41.49%0.08920%0.197CC..EExtended strand (participates in β ladder)trans-127.3126.3174-49.5175.5000108.2F98 P109 F123 N125 F128 L139 V142F98-L131 HydrophobicContact CE1-CB 3.92Å; F98-L131 HydrophobicContact CE1-CD1 3.89Å; F98-L131 HydrophobicContact CE1-CG 4.28Å; F98-L131 HydrophobicContact CZ-CB 4.27Å; P109-L131 VanDerWaalsContact CD-CD1 3.48Å; P109-L131 HydrophobicContact CG-CD1 3.94Å; F123-L131 HydrophobicContact CD1-CD1 4.08Å; F123-L131 HydrophobicContact CD1-CD2 4.09Å; F123-L131 HydrophobicContact CE1-CD2 3.88Å; N125-L131 HydrophobicContact CB-CD1 4.23Å; F128-L131 HydrophobicContact CB-CD2 3.87Å; F128-L131 HydrophobicContact CD2-CD2 4.47Å; L131-L139 HydrophobicContact CB-CD1 3.84Å; L131-L139 HydrophobicContact CD2-CD1 4.26Å; L131-V142 HydrophobicContact CD2-CB 4.22Å; L131-V142 HydrophobicContact CD2-CG1 3.51Å
132I94.4Very high92.4Very high9 Ų936.4 Ų36.45%0.04618%0.178CC..EExtended strand (participates in β ladder)trans-105.3120.5-180-61.495.1000108.2L140 M141 F182 W194I132-L140 PolarHBondContact O-N 2.85Å; I132-M141 HydrophobicContact CB-CB 4.11Å; I132-M141 HydrophobicContact CD1-CB 3.92Å; I132-M141 HydrophobicContact CG1-CB 4.49Å; I132-M141 PolarHBondContact N-O 3.19Å; I132-M141 PolarHBondContact O-N 2.62Å; I132-F182 HydrophobicContact CG2-CB 4.26Å; I132-F182 HydrophobicContact CG2-CD1 4.41Å; I132-F182 HydrophobicContact CG2-CD2 3.34Å; I132-F182 HydrophobicContact CG2-CE2 3.64Å; I132-F182 HydrophobicContact CG2-CG 3.75Å; I132-F182 HydrophobicContact CG2-CZ 4.3Å; I132-W194 HydrophobicContact CD1-CH2 4.37Å; I132-W194 HydrophobicContact CG1-CH2 3.98Å; I132-W194 HydrophobicContact CG1-CZ3 4.43Å; I132-W194 HydrophobicContact CG2-CH2 4.28Å
133M94Very high92.5Very high17 Ų1735.8 Ų35.88%0.08417%0.174CC..EExtended strand (participates in β ladder)trans-117.5143-172.1-57.2-68.9-63.300109.4L96 F98 P109 V122 F137 R138 L139L96-M133 HydrophobicContact CD1-CE 4.31Å; L96-M133 HydrophobicContact CD2-CB 3.89Å; L96-M133 HydrophobicContact CD2-CE 4.14Å; L96-M133 HydrophobicContact CD2-CG 3.91Å; F98-M133 HydrophobicContact CE2-CG 4.29Å; F98-M133 HydrophobicContact CZ-CG 3.84Å; P109-M133 HydrophobicContact CB-CE 4.28Å; P109-M133 HydrophobicContact CB-SD 4.49Å; P109-M133 HydrophobicContact CG-SD 4.47Å; V122-M133 HydrophobicContact CG1-CE 4Å; M133-F137 VanDerWaalsContact CE-C 3.46Å; M133-F137 WeakPolarHBondContact CE-O 3.31Å; M133-R138 WeakPolarHBondContact CA-O 3.38Å; M133-L139 HydrophobicContact CE-CB 4.48Å; M133-L139 VanDerWaalsContact SD-CA 3.54Å; M133-L139 HydrophobicContact SD-CB 3.84Å; M133-L139 HydrophobicContact SD-CD1 3.47Å; M133-L139 WeakPolarHBondContact SD-CD1 3.47Å; M133-L139 HydrophobicContact SD-CG 4.29Å
134D91.9Very high92.6Very high4 Ų436.8 Ų36.82%0.02118%0.18CC..  trans-83.5172.9171763000112.7R136 F137 R138 L140 S185 S189D134-R136 PolarHBondContact O-N 2.89Å; D134-R136 VanDerWaalsContact OD1-C 3.23Å; D134-R136 VanDerWaalsContact OD1-CA 3.28Å; D134-R136 WeakPolarHBondContact OD1-CA 3.38Å; D134-R136 WeakPolarHBondContact OD1-CB 3.35Å; D134-R136 PolarHBondContact OD1-N 3.49Å; D134-F137 WeakPolarHBondContact O-CA 3.41Å; D134-F137 PolarHBondContact O-N 2.94Å; D134-F137 PolarHBondContact OD1-N 3.36Å; D134-R138 PolarHBondContact N-O 3.03Å; D134-R138 WeakPolarHBondContact OD1-CB 3.37Å; D134-R138 PolarHBondContact OD1-N 3.49Å; D134-R138 IonicContact OD1-NE 2.98Å; D134-R138 IonicContact OD2-CZ 3.74Å; D134-R138 IonicContact OD2-NE 3.3Å; D134-R138 PolarHBondContact OD2-NE 3.47Å; D134-R138 IonicContact OD2-NH2 2.97Å; D134-R138 PolarHBondContact OD2-NH2 2.98Å; D134-L140 HydrophobicContact CB-CD1 3.85Å; D134-L140 HydrophobicContact CB-CD2 4.09Å; D134-L140 HydrophobicContact CB-CG 3.97Å; D134-S185 WeakPolarHBondContact CB-OG 3.3Å; D134-S189 PolarHBondContact OD2-OG 2.79Å
135D87.8Confident92.7Very high40 Ų4033.5 Ų33.521%0.21417%0.169CC..THydrogen-bonded Turntrans-68.31177.4-59.5-32.7000113.7S88S88-D135 WeakPolarHBondContact CB-O 3.32Å; S88-D135 PolarHBondContact OG-O 3.39Å
136R90.1Very high92.8Very high89 Ų8935 Ų3534%0.33618%0.179SC..THydrogen-bonded Turntrans-107.79.7170.6-61.6-173.7-176.9175.27.7111.9W90 R91 D134 R138 R187W90-R136 HydrophobicContact CB-CG 4.13Å; W90-R136 HydrophobicContact CG-CG 4.12Å; R91-R136 WeakPolarHBondContact CD-O 3.21Å; R91-R136 PolarHBondContact NH1-O 2.85Å; R91-R136 VanDerWaalsContact NH1-O 3.15Å; D134-R136 PolarHBondContact O-N 2.89Å; D134-R136 VanDerWaalsContact OD1-C 3.23Å; D134-R136 VanDerWaalsContact OD1-CA 3.28Å; D134-R136 WeakPolarHBondContact OD1-CA 3.38Å; D134-R136 WeakPolarHBondContact OD1-CB 3.35Å; D134-R136 PolarHBondContact OD1-N 3.49Å; R136-R138 VanDerWaalsContact C-N 3.31Å; R136-R138 HydrophobicContact CB-CG 4.41Å; R136-R187 PolarHBondContact NH2-O 3.46Å
137F93.1Very high93.1Very high3 Ų335.9 Ų35.91%0.01318%0.183CC..SBendtrans62.933.9-178.1-48.6-33.2000113.4R91 E94 L96 I111 M133 D134R91-F137 HydrophobicContact CB-CE2 4.19Å; E94-F137 HydrophobicContact CB-CE2 4.13Å; L96-F137 HydrophobicContact CB-CD1 3.5Å; L96-F137 VanDerWaalsContact CB-CD1 3.5Å; L96-F137 HydrophobicContact CB-CD2 4.23Å; L96-F137 HydrophobicContact CB-CE1 3.49Å; L96-F137 VanDerWaalsContact CB-CE1 3.49Å; L96-F137 HydrophobicContact CB-CE2 4.24Å; L96-F137 HydrophobicContact CB-CG 3.87Å; L96-F137 HydrophobicContact CB-CZ 3.87Å; L96-F137 HydrophobicContact CD1-CB 4.3Å; L96-F137 HydrophobicContact CD1-CG 4.46Å; L96-F137 HydrophobicContact CD2-CB 4.44Å; L96-F137 HydrophobicContact CD2-CD1 3.8Å; L96-F137 HydrophobicContact CD2-CE1 4.4Å; L96-F137 HydrophobicContact CD2-CG 4.35Å; L96-F137 HydrophobicContact CG-CD1 4.18Å; L96-F137 HydrophobicContact CG-CG 4.47Å; I111-F137 HydrophobicContact CD1-CB 3.81Å; I111-F137 HydrophobicContact CD1-CD2 4Å; I111-F137 HydrophobicContact CD1-CG 4.4Å; I111-F137 HydrophobicContact CG1-CB 4.09Å; I111-F137 HydrophobicContact CG1-CD2 3.82Å; I111-F137 HydrophobicContact CG1-CG 4.31Å; I111-F137 HydrophobicContact CG2-CD2 4.43Å; M133-F137 VanDerWaalsContact CE-C 3.46Å; M133-F137 WeakPolarHBondContact CE-O 3.31Å; D134-F137 WeakPolarHBondContact O-CA 3.41Å; D134-F137 PolarHBondContact O-N 2.94Å; D134-F137 PolarHBondContact OD1-N 3.36Å
138R91.5Very high93.4Very high99 Ų9936.7 Ų36.737%0.37419%0.188SC..  trans-95.9136.7170.8-57.8179.4-67.5176.1-0.6109.8M133 D134 R136 L140 S189M133-R138 WeakPolarHBondContact CA-O 3.38Å; D134-R138 PolarHBondContact N-O 3.03Å; D134-R138 WeakPolarHBondContact OD1-CB 3.37Å; D134-R138 PolarHBondContact OD1-N 3.49Å; D134-R138 IonicContact OD1-NE 2.98Å; D134-R138 IonicContact OD2-CZ 3.74Å; D134-R138 IonicContact OD2-NE 3.3Å; D134-R138 PolarHBondContact OD2-NE 3.47Å; D134-R138 IonicContact OD2-NH2 2.97Å; D134-R138 PolarHBondContact OD2-NH2 2.98Å; R136-R138 VanDerWaalsContact C-N 3.31Å; R136-R138 HydrophobicContact CB-CG 4.41Å; R138-L140 PolarHBondContact O-N 3.11Å; R138-S189 PolarHBondContact NH2-OG 3.33Å
139L94.4Very high93.5Very high7 Ų735.9 Ų35.94%0.03718%0.184CC..EExtended strand (participates in β ladder)trans-69.6119173.2-173.466.9000110.1F123 L131 M133 V142 A156 Y164 F166F123-L139 HydrophobicContact CB-CD2 4.33Å; F123-L139 HydrophobicContact CD1-CD2 3.9Å; F123-L139 HydrophobicContact CD2-CD2 4.03Å; F123-L139 HydrophobicContact CE1-CD2 4.2Å; F123-L139 HydrophobicContact CE2-CD2 4.35Å; F123-L139 HydrophobicContact CG-CD2 3.82Å; F123-L139 HydrophobicContact CZ-CD2 4.42Å; L131-L139 HydrophobicContact CB-CD1 3.84Å; L131-L139 HydrophobicContact CD2-CD1 4.26Å; M133-L139 HydrophobicContact CE-CB 4.48Å; M133-L139 VanDerWaalsContact SD-CA 3.54Å; M133-L139 HydrophobicContact SD-CB 3.84Å; M133-L139 HydrophobicContact SD-CD1 3.47Å; M133-L139 WeakPolarHBondContact SD-CD1 3.47Å; M133-L139 HydrophobicContact SD-CG 4.29Å; L139-V142 HydrophobicContact CD1-CG1 3.9Å; L139-V142 HydrophobicContact CD2-CG1 3.86Å; L139-V142 HydrophobicContact CG-CG1 4.16Å; L139-A156 HydrophobicContact CB-CB 4.35Å; L139-A156 HydrophobicContact CD2-CB 3.84Å; L139-A156 HydrophobicContact CG-CB 3.71Å; L139-Y164 HydrophobicContact CB-CE1 3.88Å; L139-Y164 HydrophobicContact CD2-CD1 4.29Å; L139-Y164 HydrophobicContact CD2-CD2 4.46Å; L139-Y164 HydrophobicContact CD2-CE1 4.31Å; L139-Y164 HydrophobicContact CD2-CE2 4.49Å; L139-Y164 HydrophobicContact CD2-CG 4.37Å; L139-F166 HydrophobicContact CD2-CE1 4.19Å
140L94.1Very high93.8Very high14 Ų1437 Ų377%0.07319%0.185CC..EExtended strand (participates in β ladder)trans-96.4-48.4178.2-62.2-175.4000111.8I132 D134 R138 A156 F182 I192I132-L140 PolarHBondContact O-N 2.85Å; D134-L140 HydrophobicContact CB-CD1 3.85Å; D134-L140 HydrophobicContact CB-CD2 4.09Å; D134-L140 HydrophobicContact CB-CG 3.97Å; R138-L140 PolarHBondContact O-N 3.11Å; L140-A156 PolarHBondContact O-N 3.4Å; L140-F182 HydrophobicContact CD1-CE2 4.46Å; L140-I192 HydrophobicContact CB-CD1 4.27Å; L140-I192 HydrophobicContact CD1-CD1 3.98Å; L140-I192 HydrophobicContact CD1-CG1 4.11Å
141M95.1Very high94.1Very high2 Ų234.8 Ų34.81%0.0117%0.17CC..EExtended strand (participates in β ladder)trans-145.5159.6-176.1-66.3179.676.400111.1I132 Y153 Y154 V169 I192 W194 L210I132-M141 HydrophobicContact CB-CB 4.11Å; I132-M141 HydrophobicContact CD1-CB 3.92Å; I132-M141 HydrophobicContact CG1-CB 4.49Å; I132-M141 PolarHBondContact N-O 3.19Å; I132-M141 PolarHBondContact O-N 2.62Å; M141-Y153 HydrophobicContact CE-CD1 4.28Å; M141-Y153 HydrophobicContact CE-CG 4.48Å; M141-Y154 CarbonylContact C-O 3.54Å; M141-Y154 WeakPolarHBondContact CA-O 3Å; M141-Y154 WeakPolarHBondContact CB-O 3.43Å; M141-V169 HydrophobicContact CE-CB 4.32Å; M141-V169 HydrophobicContact CE-CG1 4.4Å; M141-V169 HydrophobicContact CE-CG2 4.14Å; M141-I192 HydrophobicContact CG-CD1 4.13Å; M141-I192 HydrophobicContact SD-CD1 3.61Å; M141-W194 HydrophobicContact SD-CH2 4.36Å; M141-W194 HydrophobicContact SD-CZ2 3.75Å; M141-L210 HydrophobicContact SD-CD2 4.25Å
142V95.8Very high94.2Very high0 Ų035.3 Ų35.30%017%0.172CC..EExtended strand (participates in β ladder)trans-134.8154.7173.3-61.70000109.3F128 S130 L131 L139 Y154 F166F128-V142 HydrophobicContact CB-CB 4.11Å; F128-V142 HydrophobicContact CD1-CB 3.66Å; F128-V142 HydrophobicContact CD1-CG2 3.56Å; F128-V142 HydrophobicContact CD2-CB 3.92Å; F128-V142 HydrophobicContact CD2-CG1 4.05Å; F128-V142 HydrophobicContact CD2-CG2 4.06Å; F128-V142 HydrophobicContact CE1-CB 4Å; F128-V142 HydrophobicContact CE1-CG2 3.35Å; F128-V142 HydrophobicContact CE2-CB 4.24Å; F128-V142 HydrophobicContact CE2-CG1 4.37Å; F128-V142 HydrophobicContact CE2-CG2 3.86Å; F128-V142 HydrophobicContact CG-CB 3.62Å; F128-V142 HydrophobicContact CG-CG1 4.19Å; F128-V142 HydrophobicContact CG-CG2 3.92Å; F128-V142 HydrophobicContact CZ-CB 4.28Å; F128-V142 HydrophobicContact CZ-CG2 3.51Å; S130-V142 WeakPolarHBondContact O-CA 3.33Å; L131-V142 HydrophobicContact CD2-CB 4.22Å; L131-V142 HydrophobicContact CD2-CG1 3.51Å; L139-V142 HydrophobicContact CD1-CG1 3.9Å; L139-V142 HydrophobicContact CD2-CG1 3.86Å; L139-V142 HydrophobicContact CG-CG1 4.16Å; V142-Y154 HydrophobicContact CG2-CD2 4.25Å; V142-Y154 HydrophobicContact CG2-CG 4.44Å; V142-Y154 PolarHBondContact N-O 3.13Å; V142-Y154 PolarHBondContact O-N 2.79Å; V142-F166 HydrophobicContact CB-CE1 4.39Å; V142-F166 HydrophobicContact CG1-CD1 4.38Å; V142-F166 HydrophobicContact CG1-CE1 3.76Å; V142-F166 HydrophobicContact CG2-CD1 3.45Å; V142-F166 VanDerWaalsContact CG2-CD1 3.45Å; V142-F166 HydrophobicContact CG2-CE1 3.66Å; V142-F166 HydrophobicContact CG2-CG 4.24Å
143A96.1Very high94.3Very high1 Ų135.8 Ų35.81%0.00817%0.174CC..EExtended strand (participates in β ladder)trans-132.4148.9174.800000111.8F128 S129 S130 T151 N152 Y153F128-A143 CarbonylContact C-O 3.52Å; F128-A143 VanDerWaalsContact CA-O 3.31Å; F128-A143 WeakPolarHBondContact CA-O 3.28Å; F128-A143 WeakPolarHBondContact CB-O 3.09Å; S129-A143 PolarHBondContact N-O 3.18Å; S129-A143 PolarHBondContact OG-O 3.07Å; S129-A143 VanDerWaalsContact OG-O 3.14Å; S130-A143 PolarHBondContact N-O 2.91Å; S130-A143 PolarHBondContact O-N 2.88Å; A143-T151 HydrophobicContact CB-CG2 3.9Å; A143-N152 VanDerWaalsContact CA-O 3.22Å; A143-N152 WeakPolarHBondContact CA-O 3.33Å; A143-Y153 HydrophobicContact CB-CD1 3.79Å; A143-Y153 HydrophobicContact CB-CE1 3.71Å; A143-Y153 HydrophobicContact CB-CG 4.31Å
144N95.2Very high94.4Very high35 Ų3537.4 Ų37.419%0.18718%0.179CC..EExtended strand (participates in β ladder)trans-128.3152.816667.6-4.1000110F128 T151 N152F128-N144 HydrophobicContact CD1-CB 4.31Å; N144-T151 CarbonylContact O-C 3.6Å; N144-T151 VanDerWaalsContact O-CA 3.31Å; N144-T151 WeakPolarHBondContact O-CA 3.43Å; N144-N152 PolarHBondContact N-O 2.93Å; N144-N152 PolarHBondContact O-N 2.85Å; N144-N152 VanDerWaalsContact OD1-CB 3.3Å; N144-N152 WeakPolarHBondContact OD1-CB 3.49Å; N144-N152 PolarHBondContact OD1-ND2 2.88Å; N144-N152 PolarHBondContact OD1-O 3.49Å
145V95.5Very high94.5Very high31 Ų3140 Ų4019%0.18819%0.19CC..EExtended strand (participates in β ladder)trans-102.8128.5174.3-175.80000108M150 T151 L489 A490 V493V145-M150 CarbonylContact C-O 3.43Å; V145-M150 WeakPolarHBondContact CA-O 3.3Å; V145-T151 HydrophobicContact CG2-CG2 4.41Å; V145-L489 VanDerWaalsContact CB-O 3.3Å; V145-L489 WeakPolarHBondContact CB-O 3.32Å; V145-L489 WeakPolarHBondContact CG2-O 3.5Å; V145-A490 HydrophobicContact CG2-CB 4.39Å; V145-V493 HydrophobicContact CG1-CG2 3.75Å
146S95.1Very high94.8Very high35 Ų3538.5 Ų38.525%0.24518%0.184CC..  trans-79.9167.5173480000111.4D148 G149 M150S146-D148 WeakPolarHBondContact CB-OD1 3.47Å; S146-D148 PolarHBondContact O-N 3.21Å; S146-D148 PolarHBondContact OG-OD1 2.79Å; S146-G149 PolarHBondContact O-N 2.99Å; S146-M150 PolarHBondContact N-O 2.8Å; S146-M150 WeakPolarHBondContact OG-CB 3.3Å; S146-M150 PolarHBondContact OG-N 3.18Å; S146-M150 PolarHBondContact OG-O 2.83Å
147E92.8Very high94.9Very high145 Ų14536.7 Ų36.768%0.67818%0.18SC*.THydrogen-bonded Turntrans-60.8-30.9-176.1-169.5176.717200113.4G149 G492 K495E147-G149 VanDerWaalsContact C-N 3.26Å; E147-G149 PolarHBondContact O-N 3.42Å; E147-G492 WeakPolarHBondContact O-CA 3.47Å; E147-K495 WeakPolarHBondContact O-CE 3.29Å; E147-K495 PolarHBondContact O-NZ 2.98Å; E147-K495 IonicContact OE1-NZ 2.88Å; E147-K495 PolarHBondContact OE1-NZ 3.31Å
148D94Very high94.7Very high102 Ų10242.1 Ų42.155%0.54521%0.207SC..THydrogen-bonded Turntrans-81.21.4175.965.8-10.4000114S146 M150 V496S146-D148 WeakPolarHBondContact CB-OD1 3.47Å; S146-D148 PolarHBondContact O-N 3.21Å; S146-D148 PolarHBondContact OG-OD1 2.79Å; D148-M150 PolarHBondContact OD1-N 3.11Å; D148-V496 WeakPolarHBondContact O-CG2 3.34Å
149G95.8Very high94.7Very high1 Ų143.7 Ų43.71%0.0122%0.216CC..SBendtrans83.17.7178.600000115.2S146 E147 G492S146-G149 PolarHBondContact O-N 2.99Å; E147-G149 VanDerWaalsContact C-N 3.26Å; E147-G149 PolarHBondContact O-N 3.42Å; G149-G492 WeakPolarHBondContact CA-O 3.42Å
150M97.7Very high94.5Very high72 Ų7246.2 Ų46.236%0.35524%0.235SC..  trans-70.7150.2165.6-58.9-73.9-16500110.2V145 S146 D148 T171 P173V145-M150 CarbonylContact C-O 3.43Å; V145-M150 WeakPolarHBondContact CA-O 3.3Å; S146-M150 PolarHBondContact N-O 2.8Å; S146-M150 WeakPolarHBondContact OG-CB 3.3Å; S146-M150 PolarHBondContact OG-N 3.18Å; S146-M150 PolarHBondContact OG-O 2.83Å; D148-M150 PolarHBondContact OD1-N 3.11Å; M150-T171 HydrophobicContact CB-CG2 3.67Å; M150-T171 HydrophobicContact CG-CG2 4.24Å; M150-T171 HydrophobicContact SD-CG2 4.4Å; M150-P173 WeakPolarHBondContact SD-CA 3.5Å; M150-P173 HydrophobicContact SD-CB 3.82Å
151T97.6Very high94.1Very high8 Ų853.6 Ų53.65%0.04927%0.271CS..EExtended strand (participates in β ladder)trans-116119.7176.3-55.20000109.7A143 N144 V145 Y153 T171 L172 A177A143-T151 HydrophobicContact CB-CG2 3.9Å; N144-T151 CarbonylContact O-C 3.6Å; N144-T151 VanDerWaalsContact O-CA 3.31Å; N144-T151 WeakPolarHBondContact O-CA 3.43Å; V145-T151 HydrophobicContact CG2-CG2 4.41Å; T151-Y153 HydrophobicContact CG2-CD2 4.14Å; T151-Y153 HydrophobicContact CG2-CE2 3.44Å; T151-Y153 VanDerWaalsContact CG2-CE2 3.44Å; T151-T171 CarbonylContact O-C 3.12Å; T151-T171 WeakPolarHBondContact O-CA 3.37Å; T151-L172 PolarHBondContact N-O 3.34Å; T151-L172 PolarHBondContact O-N 2.79Å; T151-A177 HydrophobicContact CG2-CB 4.47Å; T151-A177 WeakPolarHBondContact OG1-CB 3.43Å
152N97.4Very high93.5Very high27 Ų2758 Ų5814%0.14429%0.294CS..EExtended strand (participates in β ladder)trans-97.4130.5177.1-44.4-76.3000109.8A143 N144 Y154 F168 T171A143-N152 VanDerWaalsContact CA-O 3.22Å; A143-N152 WeakPolarHBondContact CA-O 3.33Å; N144-N152 PolarHBondContact N-O 2.93Å; N144-N152 PolarHBondContact O-N 2.85Å; N144-N152 VanDerWaalsContact OD1-CB 3.3Å; N144-N152 WeakPolarHBondContact OD1-CB 3.49Å; N144-N152 PolarHBondContact OD1-ND2 2.88Å; N144-N152 PolarHBondContact OD1-O 3.49Å; N152-Y154 HydrophobicContact CB-CE2 3.74Å; N152-F168 HydrophobicContact CB-CE2 4.2Å; N152-T171 VanDerWaalsContact OD1-CG2 3.3Å; N152-T171 WeakPolarHBondContact OD1-CG2 3.46Å; N152-T171 PolarHBondContact OD1-OG1 3.37Å
153Y95.6Very high93.2Very high19 Ų1966.8 Ų66.88%0.07533%0.327CS..EExtended strand (participates in β ladder)trans-106.3135.6179.4-71.6-94.6000110.1M141 A143 T151 V169 K170 L172 L180M141-Y153 HydrophobicContact CE-CD1 4.28Å; M141-Y153 HydrophobicContact CE-CG 4.48Å; A143-Y153 HydrophobicContact CB-CD1 3.79Å; A143-Y153 HydrophobicContact CB-CE1 3.71Å; A143-Y153 HydrophobicContact CB-CG 4.31Å; T151-Y153 HydrophobicContact CG2-CD2 4.14Å; T151-Y153 HydrophobicContact CG2-CE2 3.44Å; T151-Y153 VanDerWaalsContact CG2-CE2 3.44Å; Y153-V169 PolarHBondContact O-N 2.88Å; Y153-K170 HydrophobicContact CD2-CG 4.34Å; Y153-K170 PolarHBondContact N-O 3.19Å; Y153-K170 PolarHBondContact O-N 3.12Å; Y153-L172 HydrophobicContact CD2-CD1 4.25Å; Y153-L172 HydrophobicContact CD2-CG 4.38Å; Y153-L172 HydrophobicContact CE2-CB 4.36Å; Y153-L172 HydrophobicContact CE2-CD1 3.75Å; Y153-L172 HydrophobicContact CE2-CG 4.16Å; Y153-L180 HydrophobicContact CE1-CD2 3.74Å; Y153-L180 HydrophobicContact CE2-CD2 4.12Å; Y153-L180 VanDerWaalsContact CZ-CD2 3.5Å; Y153-L180 WeakPolarHBondContact OH-CD2 3.38Å
154Y95.6Very high93.1Very high52 Ų5268.6 Ų68.620%0.20433%0.334CS..EExtended strand (participates in β ladder)trans-127.3137.4178.4-50.6-100.3000110.2F128 M141 V142 N152 F166 L167 F168F128-Y154 HydrophobicContact CE1-CD2 4.14Å; F128-Y154 HydrophobicContact CE1-CE2 4.42Å; M141-Y154 CarbonylContact C-O 3.54Å; M141-Y154 WeakPolarHBondContact CA-O 3Å; M141-Y154 WeakPolarHBondContact CB-O 3.43Å; V142-Y154 HydrophobicContact CG2-CD2 4.25Å; V142-Y154 HydrophobicContact CG2-CG 4.44Å; V142-Y154 PolarHBondContact N-O 3.13Å; V142-Y154 PolarHBondContact O-N 2.79Å; N152-Y154 HydrophobicContact CB-CE2 3.74Å; Y154-F166 HydrophobicContact CD1-CB 4.45Å; Y154-F166 HydrophobicContact CG-CB 4.41Å; Y154-L167 CarbonylContact C-O 3.58Å; Y154-L167 WeakPolarHBondContact CA-O 3.42Å; Y154-F168 HydrophobicContact CD1-CB 4.05Å; Y154-F168 HydrophobicContact CD1-CD2 4.44Å; Y154-F168 HydrophobicContact CE1-CB 4.08Å; Y154-F168 HydrophobicContact CE1-CD2 4Å
155K93.9Very high93.1Very high57 Ų5770.9 Ų70.925%0.24834%0.344CS..EExtended strand (participates in β ladder)trans-77130.4168.9-176.8-180179.4-177.70109.6I157 F166 L167 V169 L210K155-I157 HydrophobicContact CG-CG1 4.45Å; K155-F166 WeakPolarHBondContact O-CA 3.28Å; K155-L167 PolarHBondContact N-O 3.04Å; K155-L167 PolarHBondContact O-N 3.23Å; K155-V169 HydrophobicContact CB-CG2 3.83Å; K155-L210 PolarHBondContact NZ-O 2.79Å
156A94.1Very high93.1Very high10 Ų1072.3 Ų72.38%0.08335%0.348CS..EExtended strand (participates in β ladder)trans-89.5125.4175.800000110.5L139 L140 Y164 F166L139-A156 HydrophobicContact CB-CB 4.35Å; L139-A156 HydrophobicContact CD2-CB 3.84Å; L139-A156 HydrophobicContact CG-CB 3.71Å; L140-A156 PolarHBondContact O-N 3.4Å; A156-Y164 HydrophobicContact CB-CD1 3.87Å; A156-Y164 HydrophobicContact CB-CE1 4.4Å; A156-F166 HydrophobicContact CB-CD1 4.08Å; A156-F166 HydrophobicContact CB-CE1 3.83Å
157I92.1Very high93.1Very high51 Ų5174.3 Ų74.326%0.26236%0.355SS..EExtended strand (participates in β ladder)trans-119.8111.1177.6-59.3-178.5000108.6K155 K159 Y164 E165 L167K155-I157 HydrophobicContact CG-CG1 4.45Å; I157-K159 HydrophobicContact CG2-CD 4.45Å; I157-K159 PolarHBondContact O-N 2.69Å; I157-Y164 CarbonylContact O-C 3.51Å; I157-Y164 WeakPolarHBondContact O-CA 3.47Å; I157-E165 PolarHBondContact N-O 3.45Å; I157-E165 PolarHBondContact O-N 3.24Å; I157-L167 HydrophobicContact CD1-CD1 3.35Å; I157-L167 HydrophobicContact CD1-CG 3.87Å
158M90.1Very high93.2Very high117 Ų11773 Ų7358%0.57635%0.347SS*.EExtended strand (participates in β ladder)trans-69118.5176.5-168.5172.163.200110.1S160 R163 Y164M158-S160 VanDerWaalsContact CG-O 3.29Å; M158-S160 WeakPolarHBondContact CG-O 3.01Å; M158-R163 WeakPolarHBondContact CA-O 3.46Å; M158-Y164 HydrophobicContact CB-CD1 4.06Å; M158-Y164 HydrophobicContact CB-CE1 3.73Å; M158-Y164 HydrophobicContact CG-CE1 4.24Å
159K91.9Very high93.1Very high131 Ų13170.6 Ų70.657%0.5734%0.336SS*.EExtended strand (participates in β ladder)trans-93.9-36.4177.6-64.8-64-178.5172.40112.3I157 R163 E165I157-K159 HydrophobicContact CG2-CD 4.45Å; I157-K159 PolarHBondContact O-N 2.69Å; K159-R163 PolarHBondContact N-O 2.94Å; K159-E165 WeakPolarHBondContact CE-OE2 3.45Å; K159-E165 HydrophobicContact CG-CB 4.08Å; K159-E165 IonicContact NZ-OE2 2.63Å; K159-E165 PolarHBondContact NZ-OE2 2.69Å
160S88.9Confident93.1Very high60 Ų6072 Ų7242%0.4234%0.342SS..EExtended strand (participates in β ladder)trans-154.8177.8172.964.80000109.3M158 L162 R163M158-S160 VanDerWaalsContact CG-O 3.29Å; M158-S160 WeakPolarHBondContact CG-O 3.01Å; S160-L162 PolarHBondContact O-N 3.33Å; S160-L162 VanDerWaalsContact O-N 3.09Å; S160-R163 PolarHBondContact N-O 3.15Å; S160-R163 PolarHBondContact O-N 3.48Å
161M85.7Confident93.1Very high170 Ų17071.4 Ų71.484%0.83734%0.342SS*.THydrogen-bonded Turntrans-50.4118.7-179.6-173.2-176.1-70.700110.9R163M161-R163 PolarHBondContact O-N 3.04Å; M161-R163 VanDerWaalsContact O-N 3.15Å
162L82.6Confident93.1Very high94 Ų9471.3 Ų71.349%0.49234%0.342SS..THydrogen-bonded Turntrans60.513.3-178.7-51.8175.5000115.9R121 V122 S160R121-L162 VanDerWaalsContact O-CD2 3.22Å; R121-L162 WeakPolarHBondContact O-CD2 3.4Å; V122-L162 WeakPolarHBondContact O-CD2 3.34Å; S160-L162 PolarHBondContact O-N 3.33Å; S160-L162 VanDerWaalsContact O-N 3.09Å
163R90.2Very high93.1Very high184 Ų18472.4 Ų72.469%0.69435%0.35SS*.EExtended strand (participates in β ladder)trans-114.5124.6174.6-68.3-165.2-179.9-164.80.5111.2M158 K159 S160 M161M158-R163 WeakPolarHBondContact CA-O 3.46Å; K159-R163 PolarHBondContact N-O 2.94Å; S160-R163 PolarHBondContact N-O 3.15Å; S160-R163 PolarHBondContact O-N 3.48Å; M161-R163 PolarHBondContact O-N 3.04Å; M161-R163 VanDerWaalsContact O-N 3.15Å
164Y93.9Very high93.1Very high40 Ų4071.7 Ų71.716%0.15735%0.348CS..EExtended strand (participates in β ladder)trans-117.8141.4-179.3-68.3-93.1000111.1F123 L139 A156 I157 M158F123-Y164 AromaticContact CD2-CD2 3.71Å; F123-Y164 HydrophobicContact CD2-CD2 3.71Å; F123-Y164 HydrophobicContact CD2-CE2 4.06Å; F123-Y164 HydrophobicContact CE2-CD2 4.19Å; L139-Y164 HydrophobicContact CB-CE1 3.88Å; L139-Y164 HydrophobicContact CD2-CD1 4.29Å; L139-Y164 HydrophobicContact CD2-CD2 4.46Å; L139-Y164 HydrophobicContact CD2-CE1 4.31Å; L139-Y164 HydrophobicContact CD2-CE2 4.49Å; L139-Y164 HydrophobicContact CD2-CG 4.37Å; A156-Y164 HydrophobicContact CB-CD1 3.87Å; A156-Y164 HydrophobicContact CB-CE1 4.4Å; I157-Y164 CarbonylContact O-C 3.51Å; I157-Y164 WeakPolarHBondContact O-CA 3.47Å; M158-Y164 HydrophobicContact CB-CD1 4.06Å; M158-Y164 HydrophobicContact CB-CE1 3.73Å; M158-Y164 HydrophobicContact CG-CE1 4.24Å
165E94.9Very high93.2Very high82 Ų8272 Ų7238%0.38335%0.351SS..EExtended strand (participates in β ladder)trans-96.5143.1157.9179.7180-146.300108.4I157 K159 L167I157-E165 PolarHBondContact N-O 3.45Å; I157-E165 PolarHBondContact O-N 3.24Å; K159-E165 WeakPolarHBondContact CE-OE2 3.45Å; K159-E165 HydrophobicContact CG-CB 4.08Å; K159-E165 IonicContact NZ-OE2 2.63Å; K159-E165 PolarHBondContact NZ-OE2 2.69Å; E165-L167 HydrophobicContact CG-CD2 4.31Å
166F95.5Very high93.4Very high62 Ų6269.9 Ų69.927%0.27234%0.342SS..EExtended strand (participates in β ladder)trans-113.5116.6179-61.3-69.8000109.9F123 F128 L139 V142 Y154 K155 A156F123-F166 HydrophobicContact CE2-CE2 4.34Å; F123-F166 AromaticContact CE2-CZ 3.65Å; F123-F166 HydrophobicContact CE2-CZ 3.65Å; F123-F166 HydrophobicContact CZ-CE1 4.47Å; F123-F166 HydrophobicContact CZ-CE2 4.26Å; F123-F166 AromaticContact CZ-CZ 3.55Å; F123-F166 HydrophobicContact CZ-CZ 3.55Å; F128-F166 HydrophobicContact CE2-CD2 4.18Å; F128-F166 HydrophobicContact CE2-CE1 4.14Å; F128-F166 AromaticContact CE2-CE2 3.76Å; F128-F166 HydrophobicContact CE2-CE2 3.76Å; F128-F166 AromaticContact CE2-CZ 3.74Å; F128-F166 HydrophobicContact CE2-CZ 3.74Å; F128-F166 HydrophobicContact CZ-CD1 4.31Å; F128-F166 AromaticContact CZ-CD2 3.95Å; F128-F166 HydrophobicContact CZ-CD2 3.95Å; F128-F166 HydrophobicContact CZ-CE1 4.37Å; F128-F166 HydrophobicContact CZ-CE2 4.02Å; F128-F166 HydrophobicContact CZ-CG 4.09Å; F128-F166 HydrophobicContact CZ-CZ 4.23Å; L139-F166 HydrophobicContact CD2-CE1 4.19Å; V142-F166 HydrophobicContact CB-CE1 4.39Å; V142-F166 HydrophobicContact CG1-CD1 4.38Å; V142-F166 HydrophobicContact CG1-CE1 3.76Å; V142-F166 HydrophobicContact CG2-CD1 3.45Å; V142-F166 VanDerWaalsContact CG2-CD1 3.45Å; V142-F166 HydrophobicContact CG2-CE1 3.66Å; V142-F166 HydrophobicContact CG2-CG 4.24Å; Y154-F166 HydrophobicContact CD1-CB 4.45Å; Y154-F166 HydrophobicContact CG-CB 4.41Å; K155-F166 WeakPolarHBondContact O-CA 3.28Å; A156-F166 HydrophobicContact CB-CD1 4.08Å; A156-F166 HydrophobicContact CB-CE1 3.83Å
167L94.4Very high93.5Very high77 Ų7770 Ų7040%0.40334%0.343SS..EExtended strand (participates in β ladder)trans-100.4126.2175.6-62.9-175.3000109.5Y154 K155 I157 E165 V169Y154-L167 CarbonylContact C-O 3.58Å; Y154-L167 WeakPolarHBondContact CA-O 3.42Å; K155-L167 PolarHBondContact N-O 3.04Å; K155-L167 PolarHBondContact O-N 3.23Å; I157-L167 HydrophobicContact CD1-CD1 3.35Å; I157-L167 HydrophobicContact CD1-CG 3.87Å; E165-L167 HydrophobicContact CG-CD2 4.31Å; L167-V169 PolarHBondContact O-N 3.03Å
168F95.2Very high93.6Very high118 Ų11870.7 Ų70.752%0.51835%0.346SS..EExtended strand (participates in β ladder)trans-58.5136.6175.3176-97.9000111.1N152 Y154 T171N152-F168 HydrophobicContact CB-CE2 4.2Å; Y154-F168 HydrophobicContact CD1-CB 4.05Å; Y154-F168 HydrophobicContact CD1-CD2 4.44Å; Y154-F168 HydrophobicContact CE1-CB 4.08Å; Y154-F168 HydrophobicContact CE1-CD2 4Å; F168-T171 VanDerWaalsContact CE2-OG1 3.3Å; F168-T171 WeakPolarHBondContact CE2-OG1 3.38Å; F168-T171 WeakPolarHBondContact CZ-OG1 3.35Å
169V93Very high93.9Very high51 Ų5165.7 Ų65.731%0.30932%0.322SS..EExtended strand (participates in β ladder)trans-113.5-61.2178.6179.10000110.3M141 Y153 K155 L167M141-V169 HydrophobicContact CE-CB 4.32Å; M141-V169 HydrophobicContact CE-CG1 4.4Å; M141-V169 HydrophobicContact CE-CG2 4.14Å; Y153-V169 PolarHBondContact O-N 2.88Å; K155-V169 HydrophobicContact CB-CG2 3.83Å; L167-V169 PolarHBondContact O-N 3.03Å
170K94.4Very high94.1Very high29 Ų2960.7 Ų60.713%0.12630%0.301CS..EExtended strand (participates in β ladder)trans-157.7163.3-174.967.8-177.798.8179.10111.9Y153 L172 E198 E208Y153-K170 HydrophobicContact CD2-CG 4.34Å; Y153-K170 PolarHBondContact N-O 3.19Å; Y153-K170 PolarHBondContact O-N 3.12Å; K170-L172 HydrophobicContact CD-CD1 4.37Å; K170-L172 HydrophobicContact CD-CD2 4.12Å; K170-L172 HydrophobicContact CD-CG 4.25Å; K170-L172 HydrophobicContact CG-CG 4.39Å; K170-E198 IonicContact NZ-OE1 2.7Å; K170-E198 IonicContact NZ-OE2 2.7Å; K170-E198 PolarHBondContact NZ-OE2 3.18Å; K170-E198 VanDerWaalsContact NZ-OE2 3.17Å; K170-E208 VanDerWaalsContact CE-OE1 3.29Å; K170-E208 WeakPolarHBondContact CE-OE1 3.46Å; K170-E208 IonicContact NZ-OE1 3.38Å; K170-E208 PolarHBondContact NZ-OE1 3.1Å; K170-E208 IonicContact NZ-OE2 3.82Å; K170-E208 PolarHBondContact NZ-OE2 3.4Å
171T97.3Very high94.4Very high60 Ų6062.7 Ų62.737%0.36830%0.304SS..EExtended strand (participates in β ladder)trans-120.7131.5170.6-60.20000108.7M150 T151 N152 F168M150-T171 HydrophobicContact CB-CG2 3.67Å; M150-T171 HydrophobicContact CG-CG2 4.24Å; M150-T171 HydrophobicContact SD-CG2 4.4Å; T151-T171 CarbonylContact O-C 3.12Å; T151-T171 WeakPolarHBondContact O-CA 3.37Å; N152-T171 VanDerWaalsContact OD1-CG2 3.3Å; N152-T171 WeakPolarHBondContact OD1-CG2 3.46Å; N152-T171 PolarHBondContact OD1-OG1 3.37Å; F168-T171 VanDerWaalsContact CE2-OG1 3.3Å; F168-T171 WeakPolarHBondContact CE2-OG1 3.38Å; F168-T171 WeakPolarHBondContact CZ-OG1 3.35Å
172L97.6Very high94.8Very high7 Ų757.2 Ų57.24%0.03728%0.276CS..EExtended strand (participates in β ladder)trans-119.4137-179.9-62.7-179.8000111T151 Y153 K170 V176 A177 L180 E198T151-L172 PolarHBondContact N-O 3.34Å; T151-L172 PolarHBondContact O-N 2.79Å; Y153-L172 HydrophobicContact CD2-CD1 4.25Å; Y153-L172 HydrophobicContact CD2-CG 4.38Å; Y153-L172 HydrophobicContact CE2-CB 4.36Å; Y153-L172 HydrophobicContact CE2-CD1 3.75Å; Y153-L172 HydrophobicContact CE2-CG 4.16Å; K170-L172 HydrophobicContact CD-CD1 4.37Å; K170-L172 HydrophobicContact CD-CD2 4.12Å; K170-L172 HydrophobicContact CD-CG 4.25Å; K170-L172 HydrophobicContact CG-CG 4.39Å; L172-V176 HydrophobicContact CB-CB 4.45Å; L172-V176 HydrophobicContact CD1-CG1 4.16Å; L172-V176 HydrophobicContact CD2-CG1 4.12Å; L172-A177 HydrophobicContact CB-CB 4.12Å; L172-L180 HydrophobicContact CD1-CD2 3.93Å; L172-E198 HydrophobicContact CD2-CG 3.98Å
173P97.7Very high95.4Very high49 Ų4953.9 Ų53.932%0.31826%0.259SS..  trans-68.8156.8171.430.8-35.2000111.1M150 K175 V176 A177M150-P173 WeakPolarHBondContact SD-CA 3.5Å; M150-P173 HydrophobicContact SD-CB 3.82Å; P173-K175 VanDerWaalsContact C-N 3.26Å; P173-K175 HydrophobicContact CG-CG 4.47Å; P173-K175 PolarHBondContact O-N 3Å; P173-K175 VanDerWaalsContact O-N 3.1Å; P173-V176 HydrophobicContact CG-CB 4.3Å; P173-V176 HydrophobicContact CG-CG2 3.9Å; P173-V176 PolarHBondContact O-N 2.91Å; P173-A177 PolarHBondContact O-N 3.31Å
174A97.1Very high95.6Very high4 Ų445.3 Ų45.33%0.03323%0.227CC..Hα-helixtrans-48-43.8-176.900000113.7V176 A177 M178 F412 V493 V496A174-V176 PolarHBondContact O-N 2.82Å; A174-A177 PolarHBondContact O-N 3.14Å; A174-M178 VanDerWaalsContact O-CB 3.27Å; A174-M178 WeakPolarHBondContact O-CB 3.32Å; A174-M178 WeakPolarHBondContact O-CG 3.36Å; A174-M178 PolarHBondContact O-N 3.03Å; A174-F412 HydrophobicContact CB-CE2 4.4Å; A174-V493 HydrophobicContact CB-CG1 4.36Å; A174-V493 HydrophobicContact CB-CG2 4.2Å; A174-V496 HydrophobicContact CB-CB 4.23Å; A174-V496 HydrophobicContact CB-CG1 4Å; A174-V496 HydrophobicContact CB-CG2 4.4Å
175K96.7Very high95.5Very high60 Ų6043.7 Ų43.726%0.26122%0.222SC..Hα-helixtrans-62.4-24.3-179.967.8174.5179.3170.50115P173 T179 K405 E406 A409 F412P173-K175 VanDerWaalsContact C-N 3.26Å; P173-K175 HydrophobicContact CG-CG 4.47Å; P173-K175 PolarHBondContact O-N 3Å; P173-K175 VanDerWaalsContact O-N 3.1Å; K175-T179 PolarHBondContact O-OG1 2.93Å; K175-K405 HydrophobicContact CD-CD 4.48Å; K175-K405 WeakPolarHBondContact O-CB 3.2Å; K175-E406 VanDerWaalsContact NZ-CD 3.26Å; K175-E406 IonicContact NZ-OE1 3.13Å; K175-E406 PolarHBondContact NZ-OE1 2.99Å; K175-E406 IonicContact NZ-OE2 2.65Å; K175-E406 PolarHBondContact NZ-OE2 2.8Å; K175-A409 HydrophobicContact CB-CB 3.79Å; K175-A409 HydrophobicContact CD-CB 3.72Å; K175-A409 HydrophobicContact CG-CB 4.42Å; K175-F412 HydrophobicContact CB-CE2 3.82Å; K175-F412 HydrophobicContact CB-CZ 4.29Å
176V97.9Very high95.4Very high11 Ų1139.9 Ų39.97%0.06720%0.204CC..Hα-helixtrans-97.1-39.3176.2-176.30000110.5L172 P173 A174 M178 T179 L180 E198 K405L172-V176 HydrophobicContact CB-CB 4.45Å; L172-V176 HydrophobicContact CD1-CG1 4.16Å; L172-V176 HydrophobicContact CD2-CG1 4.12Å; P173-V176 HydrophobicContact CG-CB 4.3Å; P173-V176 HydrophobicContact CG-CG2 3.9Å; P173-V176 PolarHBondContact O-N 2.91Å; A174-V176 PolarHBondContact O-N 2.82Å; V176-M178 VanDerWaalsContact C-N 3.32Å; V176-M178 PolarHBondContact O-N 2.89Å; V176-T179 PolarHBondContact O-N 3.24Å; V176-T179 PolarHBondContact O-OG1 3.48Å; V176-L180 PolarHBondContact O-N 2.94Å; V176-E198 HydrophobicContact CG1-CB 3.8Å; V176-E198 HydrophobicContact CG1-CG 4.3Å; V176-K405 HydrophobicContact CG2-CD 3.86Å
177A96.7Very high94.9Very high12 Ų1244.3 Ų44.310%0.09922%0.219CC..Hα-helixtrans-65.6-35179.600000112.4T151 L172 P173 A174 T179 L180T151-A177 HydrophobicContact CG2-CB 4.47Å; T151-A177 WeakPolarHBondContact OG1-CB 3.43Å; L172-A177 HydrophobicContact CB-CB 4.12Å; P173-A177 PolarHBondContact O-N 3.31Å; A174-A177 PolarHBondContact O-N 3.14Å; A177-T179 PolarHBondContact O-N 3.47Å; A177-L180 PolarHBondContact O-N 2.86Å
178M94.8Very high94.6Very high66 Ų6644.9 Ų44.933%0.32522%0.223SC..THydrogen-bonded Turntrans-69.3-15.8178-73.3178.365.800114.1A174 V176 N371 L408 F412 V493 R497A174-M178 VanDerWaalsContact O-CB 3.27Å; A174-M178 WeakPolarHBondContact O-CB 3.32Å; A174-M178 WeakPolarHBondContact O-CG 3.36Å; A174-M178 PolarHBondContact O-N 3.03Å; V176-M178 VanDerWaalsContact C-N 3.32Å; V176-M178 PolarHBondContact O-N 2.89Å; M178-N371 HydrophobicContact CE-CB 3.99Å; M178-L408 HydrophobicContact CB-CD2 4.21Å; M178-F412 HydrophobicContact SD-CE1 4.24Å; M178-F412 HydrophobicContact SD-CZ 3.85Å; M178-V493 HydrophobicContact CG-CG1 3.96Å; M178-V493 HydrophobicContact SD-CG1 3.65Å; M178-R497 HydrophobicContact CE-CG 4.46Å; M178-R497 HydrophobicContact SD-CG 4.16Å
179T95.1Very high94.3Very high12 Ų1240.1 Ų40.17%0.07420%0.204CC..THydrogen-bonded Turntrans-111.14-179.853.60000112.2K175 V176 A177 S197 I203 L408K175-T179 PolarHBondContact O-OG1 2.93Å; V176-T179 PolarHBondContact O-N 3.24Å; V176-T179 PolarHBondContact O-OG1 3.48Å; A177-T179 PolarHBondContact O-N 3.47Å; T179-S197 PolarHBondContact OG1-OG 2.89Å; T179-I203 HydrophobicContact CG2-CD1 3.97Å; T179-I203 HydrophobicContact CG2-CG1 4.28Å; T179-L408 HydrophobicContact CG2-CD2 3.59Å
180L96.2Very high94.1Very high26 Ų2640.3 Ų40.314%0.13621%0.206CC..  trans-87.2121.7175-170.574.6000109.8Y153 L172 V176 A177 W194 K195 S196Y153-L180 HydrophobicContact CE1-CD2 3.74Å; Y153-L180 HydrophobicContact CE2-CD2 4.12Å; Y153-L180 VanDerWaalsContact CZ-CD2 3.5Å; Y153-L180 WeakPolarHBondContact OH-CD2 3.38Å; L172-L180 HydrophobicContact CD1-CD2 3.93Å; V176-L180 PolarHBondContact O-N 2.94Å; A177-L180 PolarHBondContact O-N 2.86Å; L180-W194 HydrophobicContact CD1-CB 4.01Å; L180-W194 HydrophobicContact CD1-CD2 4.06Å; L180-W194 HydrophobicContact CD1-CE3 4.01Å; L180-W194 HydrophobicContact CD1-CG 4.09Å; L180-W194 HydrophobicContact CD2-CE3 4.18Å; L180-W194 HydrophobicContact CD2-CZ3 4.2Å; L180-W194 HydrophobicContact CG-CD2 4.37Å; L180-W194 HydrophobicContact CG-CE3 3.85Å; L180-W194 HydrophobicContact CG-CZ3 4.24Å; L180-K195 CarbonylContact C-O 3.57Å; L180-K195 WeakPolarHBondContact CA-O 3.43Å; L180-S196 WeakPolarHBondContact CD1-OG 3.29Å
181E95.7Very high94.1Very high102 Ų10242.6 Ų42.648%0.47721%0.213SC..EExtended strand (participates in β ladder)trans-134.6129.7179.4-179.4-172.4144.600110.5V183 W194 K195E181-V183 PolarHBondContact O-N 2.88Å; E181-W194 CarbonylContact O-C 3.48Å; E181-W194 WeakPolarHBondContact O-CA 3.22Å; E181-K195 HydrophobicContact CB-CB 4.09Å; E181-K195 PolarHBondContact N-O 3.23Å; E181-K195 PolarHBondContact O-N 2.95Å; E181-K195 WeakPolarHBondContact OE1-CE 3.21Å; E181-K195 IonicContact OE1-NZ 3.13Å; E181-K195 PolarHBondContact OE1-NZ 2.92Å; E181-K195 WeakPolarHBondContact OE2-CE 3.22Å; E181-K195 IonicContact OE2-NZ 3.24Å; E181-K195 PolarHBondContact OE2-NZ 3.13Å
182F94.9Very high94Very high56 Ų5639.7 Ų39.725%0.24620%0.196CC..EExtended strand (participates in β ladder)trans-70125.2174.6174.1-100.4000109.7I132 L140 I192 W194I132-F182 HydrophobicContact CG2-CB 4.26Å; I132-F182 HydrophobicContact CG2-CD1 4.41Å; I132-F182 HydrophobicContact CG2-CD2 3.34Å; I132-F182 HydrophobicContact CG2-CE2 3.64Å; I132-F182 HydrophobicContact CG2-CG 3.75Å; I132-F182 HydrophobicContact CG2-CZ 4.3Å; L140-F182 HydrophobicContact CD1-CE2 4.46Å; F182-I192 HydrophobicContact CD2-CG2 3.58Å; F182-I192 HydrophobicContact CE2-CG2 3.68Å; F182-W194 HydrophobicContact CB-CE3 4.06Å; F182-W194 HydrophobicContact CB-CH2 4.4Å; F182-W194 HydrophobicContact CB-CZ3 3.64Å; F182-W194 HydrophobicContact CD2-CH2 4.38Å; F182-W194 HydrophobicContact CD2-CZ3 4.28Å; F182-W194 HydrophobicContact CG-CZ3 4.48Å
183V94.7Very high93.9Very high23 Ų2340.2 Ų40.214%0.13920%0.197CC..EExtended strand (participates in β ladder)trans-96.1-61.8178.2-177.10000110.1E181 Y193 K195 L205 I229 F231 F238E181-V183 PolarHBondContact O-N 2.88Å; V183-Y193 WeakPolarHBondContact CB-O 3.34Å; V183-Y193 PolarHBondContact N-O 2.84Å; V183-K195 HydrophobicContact CG2-CB 4.36Å; V183-K195 HydrophobicContact CG2-CG 4.06Å; V183-L205 HydrophobicContact CG2-CD1 4.17Å; V183-I229 HydrophobicContact CG1-CD1 4.27Å; V183-I229 HydrophobicContact CG2-CD1 3.99Å; V183-F231 HydrophobicContact CG1-CD1 4.13Å; V183-F231 HydrophobicContact CG1-CE1 3.75Å; V183-F231 HydrophobicContact CG1-CZ 4.19Å; V183-F238 HydrophobicContact CG1-CE1 3.94Å; V183-F238 HydrophobicContact CG1-CZ 4.5Å
184V93.7Very high93.8Very high4 Ų438.2 Ų38.22%0.02418%0.183CC..EExtended strand (participates in β ladder)trans-164.1163.5-178.367.40000109.8Y193 F231 A236 F238V184-Y193 HydrophobicContact CG1-CD2 3.81Å; V184-Y193 HydrophobicContact CG1-CG 4.26Å; V184-Y193 PolarHBondContact O-N 3.46Å; V184-F231 HydrophobicContact CB-CD2 4.42Å; V184-F231 HydrophobicContact CB-CE2 3.74Å; V184-F231 HydrophobicContact CB-CZ 4.12Å; V184-F231 HydrophobicContact CG1-CD2 4.21Å; V184-F231 HydrophobicContact CG1-CE2 4.02Å; V184-F231 HydrophobicContact CG2-CE2 3.88Å; V184-A236 HydrophobicContact CG1-CB 3.79Å; V184-A236 HydrophobicContact CG2-CB 4.28Å; V184-F238 HydrophobicContact CG1-CE1 4.42Å; V184-F238 HydrophobicContact CG1-CZ 3.98Å
185S92.9Very high93.9Very high6 Ų639.1 Ų39.14%0.04219%0.186CC..EExtended strand (participates in β ladder)trans-108.5154.2169.370.40000111.5D134 R191D134-S185 WeakPolarHBondContact CB-OG 3.3Å; S185-R191 WeakPolarHBondContact CA-O 3.5Å
186S91.4Very high93.9Very high3 Ų336.3 Ų36.32%0.02118%0.175CC..  trans-61.7155.9169.363.50000111.4D188 S189 T190 R191S186-D188 VanDerWaalsContact CB-OD1 3.3Å; S186-D188 WeakPolarHBondContact CB-OD1 3.48Å; S186-D188 PolarHBondContact O-N 3.21Å; S186-D188 VanDerWaalsContact O-N 3.15Å; S186-D188 PolarHBondContact OG-OD1 3.1Å; S186-S189 VanDerWaalsContact O-CA 3.31Å; S186-S189 WeakPolarHBondContact O-CA 3.17Å; S186-S189 PolarHBondContact O-N 3.1Å; S186-T190 PolarHBondContact OG-N 2.92Å; S186-R191 PolarHBondContact N-O 3.48Å; S186-R191 PolarHBondContact OG-N 3.4Å
187R85.6Confident93.9Very high155 Ų15535.8 Ų35.859%0.58517%0.172SC*.THydrogen-bonded Turntrans-57.5-31.4-177.3-175.6178.3-179.7-167.8-0.5114.5W90 R136 S189W90-R187 VanDerWaalsContact CH2-CZ 3.49Å; W90-R187 HydrophobicContact CZ2-CG 4.08Å; R136-R187 PolarHBondContact NH2-O 3.46Å; R187-S189 VanDerWaalsContact C-N 3.33Å
188D88.2Confident93.9Very high88 Ų8837.9 Ų37.947%0.47118%0.179SC..THydrogen-bonded Turntrans-88.1-3.2175.664-11.4000112.9S186 T190S186-D188 VanDerWaalsContact CB-OD1 3.3Å; S186-D188 WeakPolarHBondContact CB-OD1 3.48Å; S186-D188 PolarHBondContact O-N 3.21Å; S186-D188 VanDerWaalsContact O-N 3.15Å; S186-D188 PolarHBondContact OG-OD1 3.1Å; D188-T190 HydrophobicContact CB-CG2 4.18Å; D188-T190 PolarHBondContact O-N 3.31Å; D188-T190 PolarHBondContact OD1-N 2.95Å; D188-T190 PolarHBondContact OD1-OG1 3.42Å; D188-T190 VanDerWaalsContact OD2-CG2 3.26Å; D188-T190 WeakPolarHBondContact OD2-CG2 3.35Å; D188-T190 PolarHBondContact OD2-OG1 3.33Å
189S88.4Confident93.8Very high19 Ų1939.4 Ų39.413%0.13318%0.182CC..SBendtrans52.637.5-175.8-52.10000113.2D134 R138 S186 R187D134-S189 PolarHBondContact OD2-OG 2.79Å; R138-S189 PolarHBondContact NH2-OG 3.33Å; S186-S189 VanDerWaalsContact O-CA 3.31Å; S186-S189 WeakPolarHBondContact O-CA 3.17Å; S186-S189 PolarHBondContact O-N 3.1Å; R187-S189 VanDerWaalsContact C-N 3.33Å
190T90Very high93.8Very high55 Ų5540.1 Ų40.134%0.33719%0.186SC..SBendtrans-94.3-15.3171.864.70000112.4S186 D188 L210S186-T190 PolarHBondContact OG-N 2.92Å; D188-T190 HydrophobicContact CB-CG2 4.18Å; D188-T190 PolarHBondContact O-N 3.31Å; D188-T190 PolarHBondContact OD1-N 2.95Å; D188-T190 PolarHBondContact OD1-OG1 3.42Å; D188-T190 VanDerWaalsContact OD2-CG2 3.26Å; D188-T190 WeakPolarHBondContact OD2-CG2 3.35Å; D188-T190 PolarHBondContact OD2-OG1 3.33Å; T190-L210 WeakPolarHBondContact O-CB 3.34Å; T190-L210 PolarHBondContact O-N 2.86Å
191R93.1Very high93.8Very high76 Ų7641.8 Ų41.829%0.28720%0.195SC..EExtended strand (participates in β ladder)trans-130.1147.1178.9-55.9179.6-77.5-77.48.1111.4S185 S186 Y193 E207 E208S185-R191 WeakPolarHBondContact CA-O 3.5Å; S186-R191 PolarHBondContact N-O 3.48Å; S186-R191 PolarHBondContact OG-N 3.4Å; R191-Y193 HydrophobicContact CB-CE2 4.41Å; R191-Y193 PolarHBondContact NE-OH 3.15Å; R191-E207 HydrophobicContact CB-CG 4.4Å; R191-E207 WeakPolarHBondContact CD-OE1 3.37Å; R191-E207 IonicContact NE-OE1 3.67Å; R191-E208 CarbonylContact C-O 3.12Å; R191-E208 VanDerWaalsContact CA-O 3.3Å; R191-E208 WeakPolarHBondContact CA-O 3.06Å
192I94.8Very high93.9Very high0 Ų039.3 Ų39.30%018%0.183CC..EExtended strand (participates in β ladder)trans-119.4138.8169.5-61.5-177.3000108.7L140 M141 F182 W194 E208 L210L140-I192 HydrophobicContact CB-CD1 4.27Å; L140-I192 HydrophobicContact CD1-CD1 3.98Å; L140-I192 HydrophobicContact CD1-CG1 4.11Å; M141-I192 HydrophobicContact CG-CD1 4.13Å; M141-I192 HydrophobicContact SD-CD1 3.61Å; F182-I192 HydrophobicContact CD2-CG2 3.58Å; F182-I192 HydrophobicContact CE2-CG2 3.68Å; I192-W194 HydrophobicContact CB-CZ2 4.34Å; I192-W194 HydrophobicContact CD1-CZ2 4.04Å; I192-W194 HydrophobicContact CG2-CD2 3.81Å; I192-W194 HydrophobicContact CG2-CE3 4.47Å; I192-W194 HydrophobicContact CG2-CG 4.21Å; I192-W194 HydrophobicContact CG2-CH2 4.24Å; I192-W194 HydrophobicContact CG2-CZ2 3.54Å; I192-E208 PolarHBondContact N-O 3.04Å; I192-E208 PolarHBondContact O-N 3.43Å; I192-L210 HydrophobicContact CD1-CD1 3.99Å; I192-L210 HydrophobicContact CD1-CD2 3.71Å; I192-L210 HydrophobicContact CD1-CG 4.17Å; I192-L210 HydrophobicContact CG1-CD1 3.92Å; I192-L210 HydrophobicContact CG1-CD2 4.06Å; I192-L210 HydrophobicContact CG1-CG 4.04Å
193Y96.3Very high94Very high18 Ų1837.6 Ų37.67%0.07118%0.176CC..EExtended strand (participates in β ladder)trans-104.6128.7172.3-61.4-84.2000109.8V183 V184 R191 V206 E207 I218 A236 F238V183-Y193 WeakPolarHBondContact CB-O 3.34Å; V183-Y193 PolarHBondContact N-O 2.84Å; V184-Y193 HydrophobicContact CG1-CD2 3.81Å; V184-Y193 HydrophobicContact CG1-CG 4.26Å; V184-Y193 PolarHBondContact O-N 3.46Å; R191-Y193 HydrophobicContact CB-CE2 4.41Å; R191-Y193 PolarHBondContact NE-OH 3.15Å; Y193-V206 CarbonylContact C-O 3.51Å; Y193-V206 VanDerWaalsContact CA-O 3.28Å; Y193-V206 WeakPolarHBondContact CA-O 3.49Å; Y193-E207 HydrophobicContact CD1-CB 4.01Å; Y193-E207 HydrophobicContact CD1-CG 4.28Å; Y193-E207 HydrophobicContact CE1-CB 3.75Å; Y193-E207 HydrophobicContact CE1-CG 3.67Å; Y193-E207 WeakPolarHBondContact CE1-OE2 3.48Å; Y193-E207 PolarHBondContact OH-OE2 2.86Å; Y193-I218 HydrophobicContact CD1-CD1 3.73Å; Y193-I218 HydrophobicContact CE1-CD1 3.86Å; Y193-A236 HydrophobicContact CD2-CB 4.48Å; Y193-A236 HydrophobicContact CE2-CB 4.18Å; Y193-F238 AromaticContact CD1-CE2 3.36Å; Y193-F238 HydrophobicContact CD1-CE2 3.36Å; Y193-F238 AromaticContact CD1-CZ 3.65Å; Y193-F238 HydrophobicContact CD1-CZ 3.65Å; Y193-F238 HydrophobicContact CD2-CE2 4.22Å; Y193-F238 HydrophobicContact CD2-CZ 4.12Å; Y193-F238 AromaticContact CE1-CE2 3.64Å; Y193-F238 HydrophobicContact CE1-CE2 3.64Å; Y193-F238 HydrophobicContact CE1-CZ 4.34Å; Y193-F238 HydrophobicContact CE2-CE2 4.46Å; Y193-F238 AromaticContact CG-CE2 3.68Å; Y193-F238 HydrophobicContact CG-CE2 3.68Å; Y193-F238 AromaticContact CG-CZ 3.51Å; Y193-F238 HydrophobicContact CG-CZ 3.51Å
194W96.5Very high94.2Very high7 Ų736.5 Ų36.53%0.02717%0.17CC..EExtended strand (participates in β ladder)trans-121.5144-177.5-58.4104.7000111.1I132 M141 L180 E181 F182 I192 L205 V206 E208I132-W194 HydrophobicContact CD1-CH2 4.37Å; I132-W194 HydrophobicContact CG1-CH2 3.98Å; I132-W194 HydrophobicContact CG1-CZ3 4.43Å; I132-W194 HydrophobicContact CG2-CH2 4.28Å; M141-W194 HydrophobicContact SD-CH2 4.36Å; M141-W194 HydrophobicContact SD-CZ2 3.75Å; L180-W194 HydrophobicContact CD1-CB 4.01Å; L180-W194 HydrophobicContact CD1-CD2 4.06Å; L180-W194 HydrophobicContact CD1-CE3 4.01Å; L180-W194 HydrophobicContact CD1-CG 4.09Å; L180-W194 HydrophobicContact CD2-CE3 4.18Å; L180-W194 HydrophobicContact CD2-CZ3 4.2Å; L180-W194 HydrophobicContact CG-CD2 4.37Å; L180-W194 HydrophobicContact CG-CE3 3.85Å; L180-W194 HydrophobicContact CG-CZ3 4.24Å; E181-W194 CarbonylContact O-C 3.48Å; E181-W194 WeakPolarHBondContact O-CA 3.22Å; F182-W194 HydrophobicContact CB-CE3 4.06Å; F182-W194 HydrophobicContact CB-CH2 4.4Å; F182-W194 HydrophobicContact CB-CZ3 3.64Å; F182-W194 HydrophobicContact CD2-CH2 4.38Å; F182-W194 HydrophobicContact CD2-CZ3 4.28Å; F182-W194 HydrophobicContact CG-CZ3 4.48Å; I192-W194 HydrophobicContact CB-CZ2 4.34Å; I192-W194 HydrophobicContact CD1-CZ2 4.04Å; I192-W194 HydrophobicContact CG2-CD2 3.81Å; I192-W194 HydrophobicContact CG2-CE3 4.47Å; I192-W194 HydrophobicContact CG2-CG 4.21Å; I192-W194 HydrophobicContact CG2-CH2 4.24Å; I192-W194 HydrophobicContact CG2-CZ2 3.54Å; W194-L205 CarbonylContact O-C 3.56Å; W194-L205 WeakPolarHBondContact O-CA 3.42Å; W194-L205 WeakPolarHBondContact O-CD1 3.4Å; W194-V206 PolarHBondContact N-O 2.92Å; W194-V206 PolarHBondContact O-N 2.84Å; W194-E208 PolarHBondContact NE1-OE2 3.28Å
195K97.8Very high94.4Very high22 Ų2236.3 Ų36.310%0.09617%0.169CC..EExtended strand (participates in β ladder)trans-79.6121.2147.2-88.2-172.7-70.5169.60106.8L180 E181 V183 I203 A204 I226 I229L180-K195 CarbonylContact C-O 3.57Å; L180-K195 WeakPolarHBondContact CA-O 3.43Å; E181-K195 HydrophobicContact CB-CB 4.09Å; E181-K195 PolarHBondContact N-O 3.23Å; E181-K195 PolarHBondContact O-N 2.95Å; E181-K195 WeakPolarHBondContact OE1-CE 3.21Å; E181-K195 IonicContact OE1-NZ 3.13Å; E181-K195 PolarHBondContact OE1-NZ 2.92Å; E181-K195 WeakPolarHBondContact OE2-CE 3.22Å; E181-K195 IonicContact OE2-NZ 3.24Å; E181-K195 PolarHBondContact OE2-NZ 3.13Å; V183-K195 HydrophobicContact CG2-CB 4.36Å; V183-K195 HydrophobicContact CG2-CG 4.06Å; K195-I203 HydrophobicContact CB-CG2 3.53Å; K195-I203 HydrophobicContact CD-CG2 4.29Å; K195-I203 HydrophobicContact CG-CG2 3.95Å; K195-A204 CarbonylContact C-O 3.45Å; K195-A204 WeakPolarHBondContact CA-O 3.46Å; K195-I226 HydrophobicContact CD-CB 4.36Å; K195-I226 HydrophobicContact CD-CG2 4.03Å; K195-I226 HydrophobicContact CG-CG2 4.4Å; K195-I229 HydrophobicContact CD-CD1 4.11Å; K195-I229 HydrophobicContact CG-CD1 3.72Å
196S97.5Very high94.6Very high2 Ų236.1 Ų36.11%0.01417%0.167CC..EExtended strand (participates in β ladder)trans-149.7137.4-174.2-1760000113L180 E198 A204L180-S196 WeakPolarHBondContact CD1-OG 3.29Å; S196-E198 VanDerWaalsContact OG-CB 3.27Å; S196-E198 WeakPolarHBondContact OG-CB 3.37Å; S196-E198 PolarHBondContact OG-N 2.9Å; S196-E198 VanDerWaalsContact OG-N 3.08Å; S196-A204 PolarHBondContact N-O 3.22Å; S196-A204 PolarHBondContact O-N 2.97Å
197S97.5Very high94.8Very high0 Ų037.4 Ų37.40%017%0.173CC..  trans-101.622.7167.371.50000112.5T179 Y199 T200 D201 K405T179-S197 PolarHBondContact OG1-OG 2.89Å; S197-Y199 VanDerWaalsContact C-N 3.35Å; S197-T200 CarbonylContact C-O 3.53Å; S197-T200 WeakPolarHBondContact CA-O 3.25Å; S197-D201 WeakPolarHBondContact CB-O 3.39Å; S197-K405 WeakPolarHBondContact O-CD 3.37Å; S197-K405 PolarHBondContact O-NZ 3.39Å
198E96.1Very high95.3Very high56 Ų5630.3 Ų30.326%0.26215%0.146SC..SBendtrans-65.2-40.6179.9-172.7180154.200111.1K170 L172 V176 S196K170-E198 IonicContact NZ-OE1 2.7Å; K170-E198 IonicContact NZ-OE2 2.7Å; K170-E198 PolarHBondContact NZ-OE2 3.18Å; K170-E198 VanDerWaalsContact NZ-OE2 3.17Å; L172-E198 HydrophobicContact CD2-CG 3.98Å; V176-E198 HydrophobicContact CG1-CB 3.8Å; V176-E198 HydrophobicContact CG1-CG 4.3Å; S196-E198 VanDerWaalsContact OG-CB 3.27Å; S196-E198 WeakPolarHBondContact OG-CB 3.37Å; S196-E198 PolarHBondContact OG-N 2.9Å; S196-E198 VanDerWaalsContact OG-N 3.08Å
199Y93.7Very high95.6Very high98 Ų9828.5 Ų28.538%0.38414%0.135SC..SBendtrans-102.5-13.4-172-50.7-70.8000114.2S197 V206 V215 V217S197-Y199 VanDerWaalsContact C-N 3.35Å; Y199-V206 HydrophobicContact CD2-CG1 4.18Å; Y199-V206 HydrophobicContact CD2-CG2 4.12Å; Y199-V206 HydrophobicContact CE2-CG1 3.88Å; Y199-V215 HydrophobicContact CD2-CG1 4.18Å; Y199-V215 HydrophobicContact CE1-CG1 4.48Å; Y199-V215 HydrophobicContact CE2-CB 4.23Å; Y199-V215 HydrophobicContact CE2-CG1 3.31Å; Y199-V215 VanDerWaalsContact CZ-CG1 3.5Å; Y199-V215 WeakPolarHBondContact OH-CG1 3.44Å; Y199-V215 WeakPolarHBondContact OH-CG2 3.16Å; Y199-V217 HydrophobicContact CD2-CG2 4.28Å; Y199-V217 HydrophobicContact CG-CG2 4.32Å
200T94.2Very high95.6Very high27 Ų2728.6 Ų28.617%0.16613%0.134CC..SBendtrans-140.2155.4-174.9490000109.3S197 K202 A204 N220 K405S197-T200 CarbonylContact C-O 3.53Å; S197-T200 WeakPolarHBondContact CA-O 3.25Å; T200-K202 VanDerWaalsContact C-N 3.33Å; T200-K202 WeakPolarHBondContact CB-O 3.49Å; T200-K202 PolarHBondContact OG1-O 2.98Å; T200-A204 WeakPolarHBondContact OG1-CB 3.46Å; T200-N220 WeakPolarHBondContact CG2-OD1 3.42Å; T200-K405 VanDerWaalsContact C-NZ 3.32Å; T200-K405 PolarHBondContact O-NZ 3.16Å
201D96.7Very high95.4Very high60 Ų6035.5 Ų35.532%0.32116%0.159SC..SBendtrans-59.8-47.5173.3171.451.1000110.9S197 G404 K405 E406S197-D201 WeakPolarHBondContact CB-O 3.39Å; D201-G404 CarbonylContact O-C 3.44Å; D201-G404 VanDerWaalsContact O-CA 3.25Å; D201-G404 WeakPolarHBondContact O-CA 3.35Å; D201-K405 PolarHBondContact O-N 3.16Å; D201-K405 PolarHBondContact OD1-N 3.31Å; D201-E406 WeakPolarHBondContact OD1-CG 3.34Å; D201-E406 PolarHBondContact OD1-N 3.45Å
202K97.4Very high95.2Very high50 Ų5036.9 Ų36.922%0.21717%0.172CC..SBendtrans-82.5150.5178.6-56.7-163.1-174.1-40.40111.9T200 A204 P221 Y223 S224 D225 F403T200-K202 VanDerWaalsContact C-N 3.33Å; T200-K202 WeakPolarHBondContact CB-O 3.49Å; T200-K202 PolarHBondContact OG1-O 2.98Å; K202-A204 PolarHBondContact O-N 3.21Å; K202-A204 VanDerWaalsContact O-N 3.1Å; K202-P221 HydrophobicContact CB-CG 3.6Å; K202-Y223 VanDerWaalsContact CE-O 3.31Å; K202-Y223 WeakPolarHBondContact CE-O 3.44Å; K202-S224 WeakPolarHBondContact CD-O 3.49Å; K202-D225 VanDerWaalsContact CA-OD1 3.23Å; K202-D225 WeakPolarHBondContact CA-OD1 3.33Å; K202-F403 PolarHBondContact NZ-O 3.25Å; K202-F403 VanDerWaalsContact NZ-O 3.12Å
203I98.2Very high94.8Very high21 Ų2139 Ų3911%0.10819%0.194CC..  trans-64.6108.9177.1-62.8178.3000109.6T179 K195 P221 D225 I226T179-I203 HydrophobicContact CG2-CD1 3.97Å; T179-I203 HydrophobicContact CG2-CG1 4.28Å; K195-I203 HydrophobicContact CB-CG2 3.53Å; K195-I203 HydrophobicContact CD-CG2 4.29Å; K195-I203 HydrophobicContact CG-CG2 3.95Å; I203-P221 WeakPolarHBondContact O-CG 3.45Å; I203-D225 HydrophobicContact CB-CB 3.8Å; I203-D225 HydrophobicContact CD1-CB 3.92Å; I203-D225 HydrophobicContact CG1-CB 3.89Å; I203-D225 PolarHBondContact N-OD1 2.93Å; I203-I226 WeakPolarHBondContact O-CD1 3.25Å; I203-I226 WeakPolarHBondContact O-CG1 3.29Å; I203-I226 PolarHBondContact O-N 3.03Å; I203-I226 VanDerWaalsContact O-N 3.17Å
204A97.8Very high94.6Very high0 Ų041.5 Ų41.50%021%0.211CC..EExtended strand (participates in β ladder)trans-94.4163.3175.700000111.7K195 S196 T200 K202 V206 V217 Y219K195-A204 CarbonylContact C-O 3.45Å; K195-A204 WeakPolarHBondContact CA-O 3.46Å; S196-A204 PolarHBondContact N-O 3.22Å; S196-A204 PolarHBondContact O-N 2.97Å; T200-A204 WeakPolarHBondContact OG1-CB 3.46Å; K202-A204 PolarHBondContact O-N 3.21Å; K202-A204 VanDerWaalsContact O-N 3.1Å; A204-V206 HydrophobicContact CB-CG2 4.24Å; A204-V217 HydrophobicContact CB-CG1 3.91Å; A204-Y219 WeakPolarHBondContact CA-O 3.33Å; A204-Y219 VanDerWaalsContact CB-O 3.29Å; A204-Y219 WeakPolarHBondContact CB-O 3.17Å
205L97.9Very high94.6Very high0 Ų043.4 Ų43.40%022%0.224CC..EExtended strand (participates in β ladder)trans-90.8127.4167.7-17959.7000108.3V183 W194 I218 Y219 I226 I229 F238 V241V183-L205 HydrophobicContact CG2-CD1 4.17Å; W194-L205 CarbonylContact O-C 3.56Å; W194-L205 WeakPolarHBondContact O-CA 3.42Å; W194-L205 WeakPolarHBondContact O-CD1 3.4Å; L205-I218 HydrophobicContact CB-CG1 4.05Å; L205-I218 HydrophobicContact CD1-CD1 4.5Å; L205-I218 HydrophobicContact CD2-CD1 3.58Å; L205-I218 HydrophobicContact CD2-CG1 3.8Å; L205-I218 HydrophobicContact CG-CD1 3.61Å; L205-I218 HydrophobicContact CG-CG1 3.53Å; L205-I218 WeakPolarHBondContact O-CG1 3.43Å; L205-I218 PolarHBondContact O-N 3.38Å; L205-Y219 PolarHBondContact N-O 2.87Å; L205-Y219 PolarHBondContact O-N 2.85Å; L205-Y219 VanDerWaalsContact O-N 3.15Å; L205-I226 HydrophobicContact CB-CD1 3.83Å; L205-I229 HydrophobicContact CB-CD1 4.47Å; L205-I229 HydrophobicContact CD1-CD1 3.67Å; L205-I229 HydrophobicContact CD2-CD1 4.27Å; L205-I229 HydrophobicContact CG-CD1 4.32Å; L205-F238 HydrophobicContact CD1-CE1 4.19Å; L205-F238 HydrophobicContact CD1-CZ 4.22Å; L205-F238 HydrophobicContact CD2-CD1 3.68Å; L205-F238 HydrophobicContact CD2-CD2 4.02Å; L205-F238 HydrophobicContact CD2-CE1 3.86Å; L205-F238 HydrophobicContact CD2-CE2 4.18Å; L205-F238 HydrophobicContact CD2-CG 3.78Å; L205-F238 HydrophobicContact CD2-CZ 4.1Å; L205-V241 HydrophobicContact CD2-CG1 4.5Å
206V97.4Very high94.5Very high2 Ų247.8 Ų47.81%0.01225%0.245CC..EExtended strand (participates in β ladder)trans-132.6135.8-167.7178.70000110.3Y193 W194 Y199 A204 V215 E216 V217Y193-V206 CarbonylContact C-O 3.51Å; Y193-V206 VanDerWaalsContact CA-O 3.28Å; Y193-V206 WeakPolarHBondContact CA-O 3.49Å; W194-V206 PolarHBondContact N-O 2.92Å; W194-V206 PolarHBondContact O-N 2.84Å; Y199-V206 HydrophobicContact CD2-CG1 4.18Å; Y199-V206 HydrophobicContact CD2-CG2 4.12Å; Y199-V206 HydrophobicContact CE2-CG1 3.88Å; A204-V206 HydrophobicContact CB-CG2 4.24Å; V206-V215 HydrophobicContact CG1-CG1 3.04Å; V206-E216 CarbonylContact C-O 3.49Å; V206-E216 VanDerWaalsContact CA-O 3.32Å; V206-E216 WeakPolarHBondContact CA-O 3.37Å; V206-E216 WeakPolarHBondContact CG1-O 3.43Å; V206-V217 HydrophobicContact CG2-CG2 4.27Å
207E96.5Very high94.4Very high29 Ų2950.4 Ų50.414%0.13626%0.26CS..EExtended strand (participates in β ladder)trans-100.3120.5172.3-179.8172.314500109.9R191 Y193 H209 V215 E216 I218R191-E207 HydrophobicContact CB-CG 4.4Å; R191-E207 WeakPolarHBondContact CD-OE1 3.37Å; R191-E207 IonicContact NE-OE1 3.67Å; Y193-E207 HydrophobicContact CD1-CB 4.01Å; Y193-E207 HydrophobicContact CD1-CG 4.28Å; Y193-E207 HydrophobicContact CE1-CB 3.75Å; Y193-E207 HydrophobicContact CE1-CG 3.67Å; Y193-E207 WeakPolarHBondContact CE1-OE2 3.48Å; Y193-E207 PolarHBondContact OH-OE2 2.86Å; E207-H209 IonicContact OE1-CE1 3.09Å; E207-H209 PolarHBondContact OE1-CE1 3.41Å; E207-H209 VanDerWaalsContact OE1-CE1 3.29Å; E207-H209 IonicContact OE1-NE2 2.79Å; E207-H209 PolarHBondContact OE1-NE2 3.02Å; E207-H209 VanDerWaalsContact OE1-NE2 3.16Å; E207-V215 CarbonylContact O-C 3.13Å; E207-V215 VanDerWaalsContact O-CA 3.3Å; E207-V215 WeakPolarHBondContact O-CA 3.16Å; E207-E216 PolarHBondContact N-O 3.11Å; E207-E216 PolarHBondContact O-N 3.37Å; E207-I218 HydrophobicContact CB-CG2 3.86Å
208E95.3Very high94.4Very high6 Ų652.5 Ų52.53%0.02827%0.271CS..EExtended strand (participates in β ladder)trans-111.9121175.3177.2166.5-171.900110.8K170 R191 I192 W194 V215K170-E208 VanDerWaalsContact CE-OE1 3.29Å; K170-E208 WeakPolarHBondContact CE-OE1 3.46Å; K170-E208 IonicContact NZ-OE1 3.38Å; K170-E208 PolarHBondContact NZ-OE1 3.1Å; K170-E208 IonicContact NZ-OE2 3.82Å; K170-E208 PolarHBondContact NZ-OE2 3.4Å; R191-E208 CarbonylContact C-O 3.12Å; R191-E208 VanDerWaalsContact CA-O 3.3Å; R191-E208 WeakPolarHBondContact CA-O 3.06Å; I192-E208 PolarHBondContact N-O 3.04Å; I192-E208 PolarHBondContact O-N 3.43Å; W194-E208 PolarHBondContact NE1-OE2 3.28Å; E208-V215 HydrophobicContact CB-CG2 4.09Å; E208-V215 HydrophobicContact CG-CG2 3.91Å
209H94.1Very high94.4Very high51 Ų5151.5 Ų51.524%0.23627%0.265CS..EExtended strand (participates in β ladder)trans-85.8114.4177.9-68.9-101.3000111.2E207 K211 N212 G213 T214E207-H209 IonicContact OE1-CE1 3.09Å; E207-H209 PolarHBondContact OE1-CE1 3.41Å; E207-H209 VanDerWaalsContact OE1-CE1 3.29Å; E207-H209 IonicContact OE1-NE2 2.79Å; E207-H209 PolarHBondContact OE1-NE2 3.02Å; E207-H209 VanDerWaalsContact OE1-NE2 3.16Å; H209-K211 PolarHBondContact O-N 2.82Å; H209-K211 VanDerWaalsContact O-N 3.15Å; H209-N212 WeakPolarHBondContact CB-OD1 3.43Å; H209-N212 PolarHBondContact O-OD1 3.31Å; H209-G213 VanDerWaalsContact O-CA 3.23Å; H209-G213 WeakPolarHBondContact O-CA 3.5Å; H209-G213 PolarHBondContact O-N 2.92Å; H209-T214 PolarHBondContact CD2-O 2.83Å; H209-T214 PolarHBondContact CD2-OG1 3.23Å; H209-T214 PolarHBondContact N-O 3.37Å
210L88Confident94.5Very high21 Ų2151.2 Ų51.211%0.1127%0.27CS..THydrogen-bonded Turntrans-69-17-173.9-69.4-179.5000114.8M141 K155 T190 I192M141-L210 HydrophobicContact SD-CD2 4.25Å; K155-L210 PolarHBondContact NZ-O 2.79Å; T190-L210 WeakPolarHBondContact O-CB 3.34Å; T190-L210 PolarHBondContact O-N 2.86Å; I192-L210 HydrophobicContact CD1-CD1 3.99Å; I192-L210 HydrophobicContact CD1-CD2 3.71Å; I192-L210 HydrophobicContact CD1-CG 4.17Å; I192-L210 HydrophobicContact CG1-CD1 3.92Å; I192-L210 HydrophobicContact CG1-CD2 4.06Å; I192-L210 HydrophobicContact CG1-CG 4.04Å
211K86.4Confident94.5Very high199 Ų19950.3 Ų50.387%0.86527%0.265SS*.THydrogen-bonded Turntrans-82.8-44.5-176.9-173.9179.4177.2-1760112.3H209H209-K211 PolarHBondContact O-N 2.82Å; H209-K211 VanDerWaalsContact O-N 3.15Å
212N88.6Confident94.3Very high105 Ų10554.9 Ų54.956%0.56128%0.282SS*.THydrogen-bonded Turntrans-114.7-7.3-173.761.3-6.4000112.6H209 T214H209-N212 WeakPolarHBondContact CB-OD1 3.43Å; H209-N212 PolarHBondContact O-OD1 3.31Å; N212-T214 HydrophobicContact CB-CG2 4.47Å; N212-T214 WeakPolarHBondContact ND2-CG2 3.44Å; N212-T214 PolarHBondContact ND2-OG1 2.84Å; N212-T214 PolarHBondContact O-N 2.81Å; N212-T214 PolarHBondContact OD1-N 2.86Å; N212-T214 PolarHBondContact OD1-OG1 2.85Å
213G86.3Confident94Very high45 Ų4558.3 Ų58.346%0.46429%0.294SS..  trans72.811.7-179.400000114.2H209H209-G213 VanDerWaalsContact O-CA 3.23Å; H209-G213 WeakPolarHBondContact O-CA 3.5Å; H209-G213 PolarHBondContact O-N 2.92Å
214T93.5Very high93.9Very high70 Ų7057.3 Ų57.343%0.42929%0.289SS..  trans-71.8142178.354.20000110.4H209 N212H209-T214 PolarHBondContact CD2-O 2.83Å; H209-T214 PolarHBondContact CD2-OG1 3.23Å; H209-T214 PolarHBondContact N-O 3.37Å; N212-T214 HydrophobicContact CB-CG2 4.47Å; N212-T214 WeakPolarHBondContact ND2-CG2 3.44Å; N212-T214 PolarHBondContact ND2-OG1 2.84Å; N212-T214 PolarHBondContact O-N 2.81Å; N212-T214 PolarHBondContact OD1-N 2.86Å; N212-T214 PolarHBondContact OD1-OG1 2.85Å
215V95.2Very high93.9Very high48 Ų4857.8 Ų57.829%0.29129%0.292SS..EExtended strand (participates in β ladder)trans-127.5133-176.7-175.30000110.3Y199 V206 E207 E208Y199-V215 HydrophobicContact CD2-CG1 4.18Å; Y199-V215 HydrophobicContact CE1-CG1 4.48Å; Y199-V215 HydrophobicContact CE2-CB 4.23Å; Y199-V215 HydrophobicContact CE2-CG1 3.31Å; Y199-V215 VanDerWaalsContact CZ-CG1 3.5Å; Y199-V215 WeakPolarHBondContact OH-CG1 3.44Å; Y199-V215 WeakPolarHBondContact OH-CG2 3.16Å; V206-V215 HydrophobicContact CG1-CG1 3.04Å; E207-V215 CarbonylContact O-C 3.13Å; E207-V215 VanDerWaalsContact O-CA 3.3Å; E207-V215 WeakPolarHBondContact O-CA 3.16Å; E208-V215 HydrophobicContact CB-CG2 4.09Å; E208-V215 HydrophobicContact CG-CG2 3.91Å
216E96Very high93.9Very high114 Ų11458 Ų5853%0.53329%0.293SS..EExtended strand (participates in β ladder)trans-125133.8178.7-176.3174.1-17800110.4V206 E207 I218V206-E216 CarbonylContact C-O 3.49Å; V206-E216 VanDerWaalsContact CA-O 3.32Å; V206-E216 WeakPolarHBondContact CA-O 3.37Å; V206-E216 WeakPolarHBondContact CG1-O 3.43Å; E207-E216 PolarHBondContact N-O 3.11Å; E207-E216 PolarHBondContact O-N 3.37Å; E216-I218 HydrophobicContact CG-CG2 4.22Å; E216-I218 PolarHBondContact O-N 2.9Å
217V96.8Very high93.7Very high56 Ų5661.5 Ų61.534%0.33931%0.309SS..EExtended strand (participates in β ladder)trans-83.1107.5170.91790000108.1Y199 A204 V206 N220Y199-V217 HydrophobicContact CD2-CG2 4.28Å; Y199-V217 HydrophobicContact CG-CG2 4.32Å; A204-V217 HydrophobicContact CB-CG1 3.91Å; V206-V217 HydrophobicContact CG2-CG2 4.27Å; V217-N220 HydrophobicContact CG1-CB 4.12Å
218I95.7Very high93.6Very high44 Ų4462.9 Ų62.923%0.22632%0.317CS..EExtended strand (participates in β ladder)trans-90.6-21.7-176.663.3171.4000112.9Y193 L205 E207 E216 F238Y193-I218 HydrophobicContact CD1-CD1 3.73Å; Y193-I218 HydrophobicContact CE1-CD1 3.86Å; L205-I218 HydrophobicContact CB-CG1 4.05Å; L205-I218 HydrophobicContact CD1-CD1 4.5Å; L205-I218 HydrophobicContact CD2-CD1 3.58Å; L205-I218 HydrophobicContact CD2-CG1 3.8Å; L205-I218 HydrophobicContact CG-CD1 3.61Å; L205-I218 HydrophobicContact CG-CG1 3.53Å; L205-I218 WeakPolarHBondContact O-CG1 3.43Å; L205-I218 PolarHBondContact O-N 3.38Å; E207-I218 HydrophobicContact CB-CG2 3.86Å; E216-I218 HydrophobicContact CG-CG2 4.22Å; E216-I218 PolarHBondContact O-N 2.9Å; I218-F238 HydrophobicContact CD1-CD2 3.91Å; I218-F238 HydrophobicContact CD1-CE2 3.8Å
219Y96.7Very high93.6Very high36 Ų3663.3 Ų63.314%0.14132%0.319CS..EExtended strand (participates in β ladder)trans-145.5125.6165.9-176.6-87.9000110.7A204 L205 P221 I226 V241 E243 M253A204-Y219 WeakPolarHBondContact CA-O 3.33Å; A204-Y219 VanDerWaalsContact CB-O 3.29Å; A204-Y219 WeakPolarHBondContact CB-O 3.17Å; L205-Y219 PolarHBondContact N-O 2.87Å; L205-Y219 PolarHBondContact O-N 2.85Å; L205-Y219 VanDerWaalsContact O-N 3.15Å; Y219-P221 HydrophobicContact CE1-CB 4.1Å; Y219-I226 HydrophobicContact CD1-CD1 3.76Å; Y219-I226 HydrophobicContact CD1-CG1 4.18Å; Y219-I226 HydrophobicContact CE1-CD1 4.42Å; Y219-I226 HydrophobicContact CE1-CG1 4.35Å; Y219-V241 HydrophobicContact CD1-CB 4.4Å; Y219-V241 HydrophobicContact CD1-CG1 4.5Å; Y219-V241 HydrophobicContact CD1-CG2 3.75Å; Y219-V241 HydrophobicContact CD2-CG2 3.64Å; Y219-V241 HydrophobicContact CE1-CB 4.33Å; Y219-V241 HydrophobicContact CE1-CG2 3.46Å; Y219-V241 VanDerWaalsContact CE1-CG2 3.46Å; Y219-V241 HydrophobicContact CE2-CG2 3.34Å; Y219-V241 HydrophobicContact CG-CG1 4.4Å; Y219-V241 HydrophobicContact CG-CG2 3.82Å; Y219-E243 PolarHBondContact OH-OE1 2.82Å; Y219-M253 HydrophobicContact CD2-SD 3.6Å; Y219-M253 HydrophobicContact CG-SD 4.13Å
220N95.6Very high93.6Very high91 Ų9161.8 Ų61.849%0.48731%0.313SS..  trans-106117.6174.5-174.429.7000109.8T200 V217T200-N220 WeakPolarHBondContact CG2-OD1 3.42Å; V217-N220 HydrophobicContact CG1-CB 4.12Å
221P94.6Very high93.9Very high9 Ų963.4 Ų63.46%0.05832%0.319CS..  trans-71157.5-178.633.2-40.8000112.7K202 I203 Y219 S224 I226 E243K202-P221 HydrophobicContact CB-CG 3.6Å; I203-P221 WeakPolarHBondContact O-CG 3.45Å; Y219-P221 HydrophobicContact CE1-CB 4.1Å; P221-S224 WeakPolarHBondContact CB-O 3.18Å; P221-S224 WeakPolarHBondContact CG-O 3.45Å; P221-I226 HydrophobicContact CB-CG1 4.15Å; P221-I226 HydrophobicContact CG-CG1 4.36Å; P221-E243 WeakPolarHBondContact CA-OE1 3.49Å; P221-E243 HydrophobicContact CB-CG 3.92Å; P221-E243 WeakPolarHBondContact CB-OE2 3.29Å
222K92.4Very high94Very high156 Ų15654.7 Ų54.768%0.67828%0.282SS*.SBendtrans-101.4-41.1-174.8-64.9178.1-177.2172.80113.3E243K222-E243 VanDerWaalsContact N-CD 3.34Å; K222-E243 PolarHBondContact N-OE1 3.06Å; K222-E243 VanDerWaalsContact N-OE1 3.16Å; K222-E243 PolarHBondContact N-OE2 3.19Å
223Y91.3Very high93.7Very high122 Ų12252.5 Ų52.548%0.47827%0.273SS..SBendtrans-112.2-44.3-165.5-53.6-70.7000112.6K202 E243 E249K202-Y223 VanDerWaalsContact CE-O 3.31Å; K202-Y223 WeakPolarHBondContact CE-O 3.44Å; Y223-E243 PolarHBondContact N-OE2 2.92Å; Y223-E249 HydrophobicContact CD2-CB 4.29Å; Y223-E249 HydrophobicContact CD2-CG 4.22Å; Y223-E249 HydrophobicContact CE2-CB 4.44Å; Y223-E249 HydrophobicContact CE2-CG 4.32Å
224S96Very high93.4Very high0 Ų053.5 Ų53.50%026%0.264CS..SBendtrans-142.2180-17572.90000110.8K202 P221 E243 Y244 G402K202-S224 WeakPolarHBondContact CD-O 3.49Å; P221-S224 WeakPolarHBondContact CB-O 3.18Å; P221-S224 WeakPolarHBondContact CG-O 3.45Å; S224-E243 PolarHBondContact N-OE2 2.81Å; S224-Y244 VanDerWaalsContact OG-C 3.28Å; S224-Y244 PolarHBondContact OG-N 2.79Å; S224-Y244 PolarHBondContact OG-O 3.17Å; S224-G402 VanDerWaalsContact CB-O 3.3Å; S224-G402 WeakPolarHBondContact CB-O 3.44Å
225D97.4Very high93.1Very high9 Ų954.1 Ų54.15%0.04827%0.268CS..SBendtrans-58.5149.5163.8-66.4-27.2000110K202 I203 H227 G402 F403 G404K202-D225 VanDerWaalsContact CA-OD1 3.23Å; K202-D225 WeakPolarHBondContact CA-OD1 3.33Å; I203-D225 HydrophobicContact CB-CB 3.8Å; I203-D225 HydrophobicContact CD1-CB 3.92Å; I203-D225 HydrophobicContact CG1-CB 3.89Å; I203-D225 PolarHBondContact N-OD1 2.93Å; D225-H227 PolarHBondContact O-N 2.85Å; D225-H227 VanDerWaalsContact O-N 3.12Å; D225-G402 VanDerWaalsContact CG-C 3.46Å; D225-G402 PolarHBondContact N-O 3.33Å; D225-G402 WeakPolarHBondContact OD2-CA 3.46Å; D225-G402 PolarHBondContact OD2-N 2.85Å; D225-F403 PolarHBondContact OD2-N 3.49Å; D225-F403 VanDerWaalsContact OD2-N 3.16Å; D225-G404 WeakPolarHBondContact OD1-CA 3.32Å; D225-G404 PolarHBondContact OD1-N 3.25Å; D225-G404 VanDerWaalsContact OD1-N 3.13Å; D225-G404 PolarHBondContact OD2-N 3.06Å
226I97.5Very high92.7Very high6 Ų652.4 Ų52.43%0.03126%0.258CS..EExtended strand (participates in β ladder)trans-59.8117.4167.2-66.8169.5000108.1K195 I203 L205 Y219 P221 I229K195-I226 HydrophobicContact CD-CB 4.36Å; K195-I226 HydrophobicContact CD-CG2 4.03Å; K195-I226 HydrophobicContact CG-CG2 4.4Å; I203-I226 WeakPolarHBondContact O-CD1 3.25Å; I203-I226 WeakPolarHBondContact O-CG1 3.29Å; I203-I226 PolarHBondContact O-N 3.03Å; I203-I226 VanDerWaalsContact O-N 3.17Å; L205-I226 HydrophobicContact CB-CD1 3.83Å; Y219-I226 HydrophobicContact CD1-CD1 3.76Å; Y219-I226 HydrophobicContact CD1-CG1 4.18Å; Y219-I226 HydrophobicContact CE1-CD1 4.42Å; Y219-I226 HydrophobicContact CE1-CG1 4.35Å; P221-I226 HydrophobicContact CB-CG1 4.15Å; P221-I226 HydrophobicContact CG-CG1 4.36Å; I226-I229 HydrophobicContact CG2-CD1 4.04Å; I226-I229 HydrophobicContact CG2-CG1 3.58Å
227H94.2Very high92.6Very high74 Ų7449.3 Ų49.334%0.34324%0.244SC..EExtended strand (participates in β ladder)trans-80.6-52.4178.4178.165.4000110.7D225 E242 Y375D225-H227 PolarHBondContact O-N 2.85Å; D225-H227 VanDerWaalsContact O-N 3.12Å; H227-E242 WeakPolarHBondContact CB-O 3.23Å; H227-E242 PolarHBondContact N-O 3.44Å; H227-Y375 AromaticContact CE1-CE1 3.91Å; H227-Y375 AromaticContact CE1-CZ 3.73Å; H227-Y375 PolarHBondContact CE1-OH 2.72Å; H227-Y375 AromaticContact ND1-CE1 3.89Å; H227-Y375 AromaticContact ND1-CZ 3.88Å; H227-Y375 PolarHBondContact ND1-OH 2.94Å
228N94.1Very high92.5Very high59 Ų5947.4 Ų47.432%0.31623%0.231SC..EExtended strand (participates in β ladder)trans-139.3156-175.4-171.727.4000111.5E242N228-E242 HydrophobicContact CB-CB 4.02Å; N228-E242 PolarHBondContact N-O 3.03Å; N228-E242 PolarHBondContact O-N 3.39Å
229I95.4Very high92.5Very high14 Ų1445.4 Ų45.47%0.07222%0.22CC..EExtended strand (participates in β ladder)trans-135121.8177.9-55.4179.5000108.1V183 K195 L205 I226 F231 F238 V241V183-I229 HydrophobicContact CG1-CD1 4.27Å; V183-I229 HydrophobicContact CG2-CD1 3.99Å; K195-I229 HydrophobicContact CD-CD1 4.11Å; K195-I229 HydrophobicContact CG-CD1 3.72Å; L205-I229 HydrophobicContact CB-CD1 4.47Å; L205-I229 HydrophobicContact CD1-CD1 3.67Å; L205-I229 HydrophobicContact CD2-CD1 4.27Å; L205-I229 HydrophobicContact CG-CD1 4.32Å; I226-I229 HydrophobicContact CG2-CD1 4.04Å; I226-I229 HydrophobicContact CG2-CG1 3.58Å; I229-F231 HydrophobicContact CG2-CD1 4.05Å; I229-F238 HydrophobicContact CG2-CD1 3.45Å; I229-F238 VanDerWaalsContact CG2-CD1 3.45Å; I229-F238 HydrophobicContact CG2-CE1 3.87Å; I229-V241 HydrophobicContact CG1-CG1 4.27Å; I229-V241 HydrophobicContact CG2-CG1 4.3Å
230I94.2Very high92.5Very high19 Ų1943.7 Ų43.710%0.09721%0.214CC..EExtended strand (participates in β ladder)trans-94.4121169.8-55.4-176.2000107.8L239 L240 I257 I275 I278I230-L239 HydrophobicContact CG2-CB 4.29Å; I230-L239 HydrophobicContact CG2-CD1 4.18Å; I230-L239 WeakPolarHBondContact O-CB 3.44Å; I230-L239 PolarHBondContact O-N 3.31Å; I230-L240 HydrophobicContact CB-CB 4.21Å; I230-L240 HydrophobicContact CD1-CB 4.44Å; I230-L240 HydrophobicContact CD1-CD2 4.05Å; I230-L240 HydrophobicContact CG1-CD2 4.27Å; I230-L240 PolarHBondContact N-O 3.01Å; I230-L240 PolarHBondContact O-N 3.12Å; I230-L240 VanDerWaalsContact O-N 3.16Å; I230-I257 HydrophobicContact CG2-CD1 4.32Å; I230-I275 HydrophobicContact CD1-CB 4.04Å; I230-I275 HydrophobicContact CD1-CD1 3.46Å; I230-I275 VanDerWaalsContact CD1-CD1 3.46Å; I230-I275 HydrophobicContact CD1-CG1 4.27Å; I230-I275 HydrophobicContact CD1-CG2 4.33Å; I230-I278 HydrophobicContact CD1-CD1 4.38Å; I230-I278 HydrophobicContact CG2-CD1 3.55Å
231F93.3Very high92.5Very high56 Ų5639.4 Ų39.425%0.24619%0.191CC..EExtended strand (participates in β ladder)trans-142.9160.2178.165.2-83.9000111V183 V184 I229 P233 E237 F238V183-F231 HydrophobicContact CG1-CD1 4.13Å; V183-F231 HydrophobicContact CG1-CE1 3.75Å; V183-F231 HydrophobicContact CG1-CZ 4.19Å; V184-F231 HydrophobicContact CB-CD2 4.42Å; V184-F231 HydrophobicContact CB-CE2 3.74Å; V184-F231 HydrophobicContact CB-CZ 4.12Å; V184-F231 HydrophobicContact CG1-CD2 4.21Å; V184-F231 HydrophobicContact CG1-CE2 4.02Å; V184-F231 HydrophobicContact CG2-CE2 3.88Å; I229-F231 HydrophobicContact CG2-CD1 4.05Å; F231-P233 HydrophobicContact CE2-CB 4.3Å; F231-P233 WeakPolarHBondContact O-CD 3.46Å; F231-E237 CarbonylContact C-O 3.59Å; F231-E237 VanDerWaalsContact CA-O 3.28Å; F231-E237 WeakPolarHBondContact CA-O 3.03Å; F231-E237 WeakPolarHBondContact CB-O 3.44Å; F231-F238 HydrophobicContact CB-CD1 3.62Å; F231-F238 HydrophobicContact CB-CE1 3.96Å; F231-F238 HydrophobicContact CB-CG 4.37Å; F231-F238 HydrophobicContact CD1-CE1 4.4Å; F231-F238 HydrophobicContact CG-CD1 4.3Å; F231-F238 HydrophobicContact CG-CE1 4.17Å
232N90Very high92.5Very high16 Ų1639.7 Ų39.79%0.08619%0.192CC..EExtended strand (participates in β ladder)trans-80.4116171-177.7-54.1000109.6Y234 T235 A236 E237 Y282N232-Y234 PolarHBondContact O-N 3.44Å; N232-Y234 VanDerWaalsContact OD1-CA 3.27Å; N232-Y234 WeakPolarHBondContact OD1-CA 3.49Å; N232-Y234 WeakPolarHBondContact OD1-CB 3.38Å; N232-Y234 VanDerWaalsContact OD1-CD2 3.29Å; N232-Y234 WeakPolarHBondContact OD1-CD2 3.44Å; N232-Y234 PolarHBondContact OD1-N 2.9Å; N232-T235 VanDerWaalsContact CB-OG1 3.31Å; N232-T235 WeakPolarHBondContact CB-OG1 2.97Å; N232-T235 VanDerWaalsContact CG-OG1 3.24Å; N232-T235 PolarHBondContact O-N 2.93Å; N232-T235 PolarHBondContact OD1-N 3.09Å; N232-T235 PolarHBondContact OD1-OG1 3.41Å; N232-A236 VanDerWaalsContact O-CA 3.26Å; N232-A236 WeakPolarHBondContact O-CA 3.18Å; N232-A236 PolarHBondContact O-N 3.18Å; N232-E237 HydrophobicContact CB-CB 4.22Å; N232-E237 PolarHBondContact N-O 2.84Å; N232-Y282 WeakPolarHBondContact CB-OH 3.36Å; N232-Y282 PolarHBondContact ND2-OH 3.35Å
233P81.5Confident92.6Very high58 Ų5832.5 Ų32.538%0.37716%0.16SC..THydrogen-bonded Turntrans-71.3-13.9-17829-35.2000113.7F231F231-P233 HydrophobicContact CE2-CB 4.3Å; F231-P233 WeakPolarHBondContact O-CD 3.46Å
234Y80Confident92.6Very high67 Ų6727 Ų2726%0.26314%0.139SC..THydrogen-bonded Turntrans-82.7-36.3178-52.7-98000112.4I89 N232 Q280I89-Y234 HydrophobicContact CB-CD1 4.13Å; I89-Y234 HydrophobicContact CB-CE1 3.7Å; I89-Y234 HydrophobicContact CD1-CD1 3.2Å; I89-Y234 HydrophobicContact CD1-CE1 3.7Å; I89-Y234 HydrophobicContact CD1-CG 3.76Å; I89-Y234 HydrophobicContact CG1-CD1 4.24Å; I89-Y234 HydrophobicContact CG1-CE1 4.29Å; I89-Y234 HydrophobicContact CG2-CD1 4.04Å; I89-Y234 HydrophobicContact CG2-CE1 3.3Å; I89-Y234 WeakPolarHBondContact CG2-OH 3.44Å; N232-Y234 PolarHBondContact O-N 3.44Å; N232-Y234 VanDerWaalsContact OD1-CA 3.27Å; N232-Y234 WeakPolarHBondContact OD1-CA 3.49Å; N232-Y234 WeakPolarHBondContact OD1-CB 3.38Å; N232-Y234 VanDerWaalsContact OD1-CD2 3.29Å; N232-Y234 WeakPolarHBondContact OD1-CD2 3.44Å; N232-Y234 PolarHBondContact OD1-N 2.9Å; Y234-Q280 HydrophobicContact CD2-CG 4.39Å; Y234-Q280 HydrophobicContact CE2-CG 3.58Å; Y234-Q280 PolarHBondContact OH-NE2 3.16Å
235T86.9Confident92.5Very high83 Ų8329.7 Ų29.751%0.50915%0.149SC..THydrogen-bonded Turntrans-111-11.7-173.959.40000113.5N232 E237N232-T235 VanDerWaalsContact CB-OG1 3.31Å; N232-T235 WeakPolarHBondContact CB-OG1 2.97Å; N232-T235 VanDerWaalsContact CG-OG1 3.24Å; N232-T235 PolarHBondContact O-N 2.93Å; N232-T235 PolarHBondContact OD1-N 3.09Å; N232-T235 PolarHBondContact OD1-OG1 3.41Å; T235-E237 PolarHBondContact O-N 2.93Å; T235-E237 WeakPolarHBondContact OG1-CB 3.36Å; T235-E237 PolarHBondContact OG1-N 2.73Å
236A88.2Confident92.1Very high11 Ų1132.2 Ų32.29%0.09116%0.161CC..THydrogen-bonded Turntrans55.727.5-165.600000112.8V184 Y193 N232 F238V184-A236 HydrophobicContact CG1-CB 3.79Å; V184-A236 HydrophobicContact CG2-CB 4.28Å; Y193-A236 HydrophobicContact CD2-CB 4.48Å; Y193-A236 HydrophobicContact CE2-CB 4.18Å; N232-A236 VanDerWaalsContact O-CA 3.26Å; N232-A236 WeakPolarHBondContact O-CA 3.18Å; N232-A236 PolarHBondContact O-N 3.18Å; A236-F238 PolarHBondContact O-N 2.83Å
237E92.2Very high91.4Very high49 Ų4933.7 Ų33.723%0.22917%0.171CC..EExtended strand (participates in β ladder)trans-80.1114175.6-178.6-177.5-155.800109.6F231 N232 T235 L239 N254 K256F231-E237 CarbonylContact C-O 3.59Å; F231-E237 VanDerWaalsContact CA-O 3.28Å; F231-E237 WeakPolarHBondContact CA-O 3.03Å; F231-E237 WeakPolarHBondContact CB-O 3.44Å; N232-E237 HydrophobicContact CB-CB 4.22Å; N232-E237 PolarHBondContact N-O 2.84Å; T235-E237 PolarHBondContact O-N 2.93Å; T235-E237 WeakPolarHBondContact OG1-CB 3.36Å; T235-E237 PolarHBondContact OG1-N 2.73Å; E237-L239 HydrophobicContact CG-CD2 4.23Å; E237-N254 PolarHBondContact OE1-ND2 3.25Å; E237-K256 IonicContact OE1-NZ 3.82Å; E237-K256 PolarHBondContact OE1-NZ 3.35Å; E237-K256 IonicContact OE2-NZ 3Å; E237-K256 PolarHBondContact OE2-NZ 2.75Å
238F95.8Very high90.9Very high16 Ų1630.8 Ų30.87%0.0716%0.159CC..EExtended strand (participates in β ladder)trans-73.1132.5175.7-61.1-74000110.9V183 V184 Y193 L205 I218 I229 F231 A236 M253 N254V183-F238 HydrophobicContact CG1-CE1 3.94Å; V183-F238 HydrophobicContact CG1-CZ 4.5Å; V184-F238 HydrophobicContact CG1-CE1 4.42Å; V184-F238 HydrophobicContact CG1-CZ 3.98Å; Y193-F238 AromaticContact CD1-CE2 3.36Å; Y193-F238 HydrophobicContact CD1-CE2 3.36Å; Y193-F238 AromaticContact CD1-CZ 3.65Å; Y193-F238 HydrophobicContact CD1-CZ 3.65Å; Y193-F238 HydrophobicContact CD2-CE2 4.22Å; Y193-F238 HydrophobicContact CD2-CZ 4.12Å; Y193-F238 AromaticContact CE1-CE2 3.64Å; Y193-F238 HydrophobicContact CE1-CE2 3.64Å; Y193-F238 HydrophobicContact CE1-CZ 4.34Å; Y193-F238 HydrophobicContact CE2-CE2 4.46Å; Y193-F238 AromaticContact CG-CE2 3.68Å; Y193-F238 HydrophobicContact CG-CE2 3.68Å; Y193-F238 AromaticContact CG-CZ 3.51Å; Y193-F238 HydrophobicContact CG-CZ 3.51Å; L205-F238 HydrophobicContact CD1-CE1 4.19Å; L205-F238 HydrophobicContact CD1-CZ 4.22Å; L205-F238 HydrophobicContact CD2-CD1 3.68Å; L205-F238 HydrophobicContact CD2-CD2 4.02Å; L205-F238 HydrophobicContact CD2-CE1 3.86Å; L205-F238 HydrophobicContact CD2-CE2 4.18Å; L205-F238 HydrophobicContact CD2-CG 3.78Å; L205-F238 HydrophobicContact CD2-CZ 4.1Å; I218-F238 HydrophobicContact CD1-CD2 3.91Å; I218-F238 HydrophobicContact CD1-CE2 3.8Å; I229-F238 HydrophobicContact CG2-CD1 3.45Å; I229-F238 VanDerWaalsContact CG2-CD1 3.45Å; I229-F238 HydrophobicContact CG2-CE1 3.87Å; F231-F238 HydrophobicContact CB-CD1 3.62Å; F231-F238 HydrophobicContact CB-CE1 3.96Å; F231-F238 HydrophobicContact CB-CG 4.37Å; F231-F238 HydrophobicContact CD1-CE1 4.4Å; F231-F238 HydrophobicContact CG-CD1 4.3Å; F231-F238 HydrophobicContact CG-CE1 4.17Å; A236-F238 PolarHBondContact O-N 2.83Å; F238-M253 HydrophobicContact CB-CB 4.01Å; F238-M253 HydrophobicContact CB-CE 4.23Å; F238-M253 HydrophobicContact CB-CG 4.15Å; F238-M253 WeakPolarHBondContact O-CB 3.45Å; F238-N254 WeakPolarHBondContact O-CB 3.21Å
239L95.5Very high90.7Very high2 Ų232.3 Ų32.31%0.0116%0.164CC..EExtended strand (participates in β ladder)trans-108.3-48.1-175.5-55.8177.4000111I230 E237 M253 N254 K256 I257 Y282I230-L239 HydrophobicContact CG2-CB 4.29Å; I230-L239 HydrophobicContact CG2-CD1 4.18Å; I230-L239 WeakPolarHBondContact O-CB 3.44Å; I230-L239 PolarHBondContact O-N 3.31Å; E237-L239 HydrophobicContact CG-CD2 4.23Å; L239-M253 PolarHBondContact O-N 3.35Å; L239-N254 HydrophobicContact CD2-CB 3.94Å; L239-N254 PolarHBondContact O-N 3.42Å; L239-N254 VanDerWaalsContact O-N 3.15Å; L239-K256 HydrophobicContact CD2-CB 4.39Å; L239-K256 HydrophobicContact CD2-CD 4.34Å; L239-I257 HydrophobicContact CB-CD1 3.69Å; L239-I257 HydrophobicContact CB-CG1 4.08Å; L239-I257 HydrophobicContact CD1-CD1 4.39Å; L239-I257 HydrophobicContact CD1-CG2 4.1Å; L239-Y282 HydrophobicContact CD1-CD1 4.09Å; L239-Y282 HydrophobicContact CD1-CE1 3.47Å; L239-Y282 VanDerWaalsContact CD1-CE1 3.47Å
240L95.6Very high90.5Very high1 Ų133.8 Ų33.81%0.00517%0.174CC..EExtended strand (participates in β ladder)trans-149.9144.3-176179.7150.9000110I230 E242 V250 G251 Y252 I257 Y261I230-L240 HydrophobicContact CB-CB 4.21Å; I230-L240 HydrophobicContact CD1-CB 4.44Å; I230-L240 HydrophobicContact CD1-CD2 4.05Å; I230-L240 HydrophobicContact CG1-CD2 4.27Å; I230-L240 PolarHBondContact N-O 3.01Å; I230-L240 PolarHBondContact O-N 3.12Å; I230-L240 VanDerWaalsContact O-N 3.16Å; L240-E242 HydrophobicContact CD2-CB 4.38Å; L240-V250 HydrophobicContact CD1-CB 3.91Å; L240-V250 HydrophobicContact CD1-CG1 4.09Å; L240-V250 HydrophobicContact CD1-CG2 4.26Å; L240-V250 HydrophobicContact CD2-CB 4.12Å; L240-V250 HydrophobicContact CD2-CG1 3.86Å; L240-V250 HydrophobicContact CG-CB 4.05Å; L240-V250 HydrophobicContact CG-CG1 4.29Å; L240-G251 WeakPolarHBondContact CA-O 3.1Å; L240-Y252 HydrophobicContact CD1-CD1 4.15Å; L240-Y252 HydrophobicContact CD1-CE1 3.87Å; L240-I257 HydrophobicContact CB-CD1 4.03Å; L240-Y261 HydrophobicContact CD1-CD1 4.48Å; L240-Y261 HydrophobicContact CD1-CD2 3.58Å; L240-Y261 HydrophobicContact CD1-CE2 3.67Å; L240-Y261 HydrophobicContact CD1-CG 4.03Å
241V96.1Very high90.5Very high0 Ų033.4 Ų33.40%017%0.174CC..EExtended strand (participates in β ladder)trans-118.1142.5169.2-65.70000108.9L205 Y219 I229 V250 G251 M253L205-V241 HydrophobicContact CD2-CG1 4.5Å; Y219-V241 HydrophobicContact CD1-CB 4.4Å; Y219-V241 HydrophobicContact CD1-CG1 4.5Å; Y219-V241 HydrophobicContact CD1-CG2 3.75Å; Y219-V241 HydrophobicContact CD2-CG2 3.64Å; Y219-V241 HydrophobicContact CE1-CB 4.33Å; Y219-V241 HydrophobicContact CE1-CG2 3.46Å; Y219-V241 VanDerWaalsContact CE1-CG2 3.46Å; Y219-V241 HydrophobicContact CE2-CG2 3.34Å; Y219-V241 HydrophobicContact CG-CG1 4.4Å; Y219-V241 HydrophobicContact CG-CG2 3.82Å; I229-V241 HydrophobicContact CG1-CG1 4.27Å; I229-V241 HydrophobicContact CG2-CG1 4.3Å; V241-V250 CarbonylContact O-C 3.49Å; V241-V250 WeakPolarHBondContact O-CA 2.96Å; V241-G251 WeakPolarHBondContact CG2-O 3.48Å; V241-G251 PolarHBondContact N-O 3.21Å; V241-G251 PolarHBondContact O-N 2.82Å; V241-M253 HydrophobicContact CG1-CG 4.03Å; V241-M253 HydrophobicContact CG2-CG 4.47Å
242E94.7Very high90.6Very high16 Ų1633.5 Ų33.58%0.07517%0.174CC..EExtended strand (participates in β ladder)trans-117127.9-178.6-174.4176.4-172.400109.4H227 N228 L240 S248 E249 V250H227-E242 WeakPolarHBondContact CB-O 3.23Å; H227-E242 PolarHBondContact N-O 3.44Å; N228-E242 HydrophobicContact CB-CB 4.02Å; N228-E242 PolarHBondContact N-O 3.03Å; N228-E242 PolarHBondContact O-N 3.39Å; L240-E242 HydrophobicContact CD2-CB 4.38Å; E242-S248 VanDerWaalsContact CD-OG 3.28Å; E242-S248 WeakPolarHBondContact CG-OG 3.47Å; E242-S248 WeakPolarHBondContact OE1-CB 3.36Å; E242-S248 PolarHBondContact OE1-OG 3.14Å; E242-E249 WeakPolarHBondContact CA-O 3.36Å; E242-V250 HydrophobicContact CG-CG1 4.46Å
243E94.5Very high90.8Very high4 Ų435.7 Ų35.72%0.01918%0.184CC..EExtended strand (participates in β ladder)trans-106.3139.1170.6-64.6179.9-130.800108.2Y219 P221 K222 Y223 S224 S248 E249Y219-E243 PolarHBondContact OH-OE1 2.82Å; P221-E243 WeakPolarHBondContact CA-OE1 3.49Å; P221-E243 HydrophobicContact CB-CG 3.92Å; P221-E243 WeakPolarHBondContact CB-OE2 3.29Å; K222-E243 VanDerWaalsContact N-CD 3.34Å; K222-E243 PolarHBondContact N-OE1 3.06Å; K222-E243 VanDerWaalsContact N-OE1 3.16Å; K222-E243 PolarHBondContact N-OE2 3.19Å; Y223-E243 PolarHBondContact N-OE2 2.92Å; S224-E243 PolarHBondContact N-OE2 2.81Å; E243-S248 WeakPolarHBondContact O-CA 3.37Å; E243-E249 PolarHBondContact N-O 2.97Å; E243-E249 PolarHBondContact O-N 3.34Å
244Y92.2Very high91.4Very high7 Ų734.7 Ų34.73%0.02718%0.176CC..EExtended strand (participates in β ladder)trans-126.785.2179.3-150.6-57.1000110.1S224 M246 R373 Y375 W376S224-Y244 VanDerWaalsContact OG-C 3.28Å; S224-Y244 PolarHBondContact OG-N 2.79Å; S224-Y244 PolarHBondContact OG-O 3.17Å; Y244-M246 WeakPolarHBondContact CE1-O 3.24Å; Y244-R373 VanDerWaalsContact O-CZ 3.28Å; Y244-R373 PolarHBondContact O-NH1 2.66Å; Y244-R373 PolarHBondContact O-NH2 3.08Å; Y244-Y375 AromaticContact CD1-CD1 3.7Å; Y244-Y375 HydrophobicContact CD1-CD1 3.7Å; Y244-Y375 HydrophobicContact CD1-CE1 4.3Å; Y244-Y375 HydrophobicContact CD2-CD1 4.24Å; Y244-Y375 AromaticContact CE1-CD1 3.93Å; Y244-Y375 HydrophobicContact CE1-CD1 3.93Å; Y244-Y375 HydrophobicContact CE2-CD1 4.44Å; Y244-Y375 AromaticContact CG-CD1 3.87Å; Y244-Y375 HydrophobicContact CG-CD1 3.87Å; Y244-Y375 HydrophobicContact CG-CE1 4.12Å; Y244-W376 PolarHBondContact OH-O 3.03Å
245Y93.4Very high92.1Very high57 Ų5736.3 Ų36.322%0.22419%0.189CC..SBendtrans-82-91.9171.5-171.1-119.4000109.9E332 L342 R373 F403Y245-E332 VanDerWaalsContact CE1-OE1 3.29Å; Y245-E332 WeakPolarHBondContact CE1-OE1 3.48Å; Y245-E332 PolarHBondContact OH-OE1 3.37Å; Y245-L342 WeakPolarHBondContact O-CD2 3.19Å; Y245-R373 PolarHBondContact O-NH2 3.16Å; Y245-R373 VanDerWaalsContact O-NH2 3.09Å; Y245-F403 HydrophobicContact CD2-CD1 4Å; Y245-F403 AromaticContact CD2-CE1 3.93Å; Y245-F403 HydrophobicContact CD2-CE1 3.93Å; Y245-F403 AromaticContact CE2-CD1 3.84Å; Y245-F403 HydrophobicContact CE2-CD1 3.84Å; Y245-F403 AromaticContact CE2-CE1 3.9Å; Y245-F403 HydrophobicContact CE2-CE1 3.9Å
246M89.3Confident92.4Very high61 Ų6137.3 Ų37.330%0.319%0.186SC..SBendtrans-83.8-44.8169.9-65-173.4177.300112.1Y244 A330 E332 L342Y244-M246 WeakPolarHBondContact CE1-O 3.24Å; M246-A330 HydrophobicContact CB-CB 4.09Å; M246-A330 HydrophobicContact CG-CB 4.26Å; M246-A330 HydrophobicContact SD-CB 4.34Å; M246-E332 HydrophobicContact CE-CG 3.67Å; M246-E332 WeakPolarHBondContact CE-OE1 3.34Å; M246-L342 HydrophobicContact CE-CD1 4.24Å; M246-L342 HydrophobicContact CG-CD1 3.76Å; M246-L342 HydrophobicContact CG-CD2 4.46Å
247T81.8Confident92.7Very high38 Ų3836.8 Ų36.823%0.23318%0.182CC..SBendtrans-135.3168.1173.965.50000109.3E249 K272 W376T247-E249 PolarHBondContact O-N 3.38Å; T247-K272 PolarHBondContact OG1-NZ 2.99Å; T247-W376 HydrophobicContact CG2-CE3 4.37Å
248S85.2Confident92.8Very high12 Ų1238.2 Ų38.28%0.08419%0.185CC..EExtended strand (participates in β ladder)trans-59130.4172.6177.30000111.9E242 E243 K272E242-S248 VanDerWaalsContact CD-OG 3.28Å; E242-S248 WeakPolarHBondContact CG-OG 3.47Å; E242-S248 WeakPolarHBondContact OE1-CB 3.36Å; E242-S248 PolarHBondContact OE1-OG 3.14Å; E243-S248 WeakPolarHBondContact O-CA 3.37Å; S248-K272 PolarHBondContact O-NZ 2.77Å
249E88.4Confident92.8Very high92 Ų9242.7 Ų42.743%0.4321%0.209SC..EExtended strand (participates in β ladder)trans-127.4140.5171.6-66.6-63.4155.800108.4Y223 E242 E243 T247Y223-E249 HydrophobicContact CD2-CB 4.29Å; Y223-E249 HydrophobicContact CD2-CG 4.22Å; Y223-E249 HydrophobicContact CE2-CB 4.44Å; Y223-E249 HydrophobicContact CE2-CG 4.32Å; E242-E249 WeakPolarHBondContact CA-O 3.36Å; E243-E249 PolarHBondContact N-O 2.97Å; E243-E249 PolarHBondContact O-N 3.34Å; T247-E249 PolarHBondContact O-N 3.38Å
250V92Very high92.9Very high45 Ų4543.2 Ų43.227%0.27321%0.213SC..EExtended strand (participates in β ladder)trans-120.3139.1-174.4-61.10000114L240 V241 E242 Y261L240-V250 HydrophobicContact CD1-CB 3.91Å; L240-V250 HydrophobicContact CD1-CG1 4.09Å; L240-V250 HydrophobicContact CD1-CG2 4.26Å; L240-V250 HydrophobicContact CD2-CB 4.12Å; L240-V250 HydrophobicContact CD2-CG1 3.86Å; L240-V250 HydrophobicContact CG-CB 4.05Å; L240-V250 HydrophobicContact CG-CG1 4.29Å; V241-V250 CarbonylContact O-C 3.49Å; V241-V250 WeakPolarHBondContact O-CA 2.96Å; E242-V250 HydrophobicContact CG-CG1 4.46Å; V250-Y261 HydrophobicContact CG1-CE1 4.17Å; V250-Y261 HydrophobicContact CG1-CE2 4.39Å; V250-Y261 VanDerWaalsContact CG1-OH 3.25Å; V250-Y261 WeakPolarHBondContact CG1-OH 2.99Å; V250-Y261 HydrophobicContact CG2-CD1 4.39Å; V250-Y261 HydrophobicContact CG2-CE1 3.76Å
251G93.4Very high92.8Very high11 Ų1144 Ų4411%0.11322%0.215CC..EExtended strand (participates in β ladder)trans-106.5121.4167.800000110.5L240 V241 M253L240-G251 WeakPolarHBondContact CA-O 3.1Å; V241-G251 WeakPolarHBondContact CG2-O 3.48Å; V241-G251 PolarHBondContact N-O 3.21Å; V241-G251 PolarHBondContact O-N 2.82Å; G251-M253 PolarHBondContact O-N 3Å
252Y95Very high92.8Very high58 Ų5846.8 Ų46.823%0.22723%0.231CC..EExtended strand (participates in β ladder)trans-78.4119.7172.5-65.2-69.6000110.3L240 R258 Y261 N262L240-Y252 HydrophobicContact CD1-CD1 4.15Å; L240-Y252 HydrophobicContact CD1-CE1 3.87Å; Y252-R258 HydrophobicContact CD1-CB 3.97Å; Y252-R258 HydrophobicContact CD1-CG 4.14Å; Y252-R258 HydrophobicContact CD2-CG 4.11Å; Y252-R258 HydrophobicContact CE1-CB 3.96Å; Y252-R258 HydrophobicContact CE1-CG 3.95Å; Y252-R258 HydrophobicContact CE2-CG 3.9Å; Y252-R258 HydrophobicContact CG-CB 4.4Å; Y252-R258 HydrophobicContact CG-CG 4.22Å; Y252-Y261 HydrophobicContact CE1-CD1 4.37Å; Y252-Y261 HydrophobicContact CE1-CG 4.27Å; Y252-Y261 WeakPolarHBondContact OH-CD1 3.2Å; Y252-N262 PolarHBondContact OH-OD1 2.03Å
253M95.4Very high92.8Very high62 Ų6249 Ų4931%0.30524%0.239SC..SBendtrans-91.1-19.9171.3-67.3-70.3-66.400111.5Y219 F238 L239 V241 G251Y219-M253 HydrophobicContact CD2-SD 3.6Å; Y219-M253 HydrophobicContact CG-SD 4.13Å; F238-M253 HydrophobicContact CB-CB 4.01Å; F238-M253 HydrophobicContact CB-CE 4.23Å; F238-M253 HydrophobicContact CB-CG 4.15Å; F238-M253 WeakPolarHBondContact O-CB 3.45Å; L239-M253 PolarHBondContact O-N 3.35Å; V241-M253 HydrophobicContact CG1-CG 4.03Å; V241-M253 HydrophobicContact CG2-CG 4.47Å; G251-M253 PolarHBondContact O-N 3Å
254N93.4Very high92.9Very high37 Ų3748.9 Ų48.920%0.19824%0.238CC..  trans-149.7152.2-178.5-161.3-69.5000110.8E237 F238 L239 K256E237-N254 PolarHBondContact OE1-ND2 3.25Å; F238-N254 WeakPolarHBondContact O-CB 3.21Å; L239-N254 HydrophobicContact CD2-CB 3.94Å; L239-N254 PolarHBondContact O-N 3.42Å; L239-N254 VanDerWaalsContact O-N 3.15Å; N254-K256 VanDerWaalsContact OD1-CB 3.29Å; N254-K256 WeakPolarHBondContact OD1-CB 3.09Å; N254-K256 WeakPolarHBondContact OD1-CD 3.5Å; N254-K256 WeakPolarHBondContact OD1-CG 3.11Å; N254-K256 PolarHBondContact OD1-N 3.43Å
255D94.6Very high92.9Very high101 Ų10151.6 Ų51.654%0.5426%0.255SS..SBendtrans-85.1-14-178-69.45.2000113I257 R258D255-I257 PolarHBondContact O-N 3.37Å; D255-R258 VanDerWaalsContact CG-NH1 3.26Å; D255-R258 PolarHBondContact O-N 2.94Å; D255-R258 IonicContact OD1-CZ 2.82Å; D255-R258 IonicContact OD1-NE 3.53Å; D255-R258 IonicContact OD1-NH1 2.86Å; D255-R258 PolarHBondContact OD1-NH1 3.2Å; D255-R258 IonicContact OD1-NH2 2.72Å; D255-R258 PolarHBondContact OD1-NH2 2.76Å; D255-R258 IonicContact OD2-NH1 3.9Å; D255-R258 PolarHBondContact OD2-NH1 2.7Å
256K93.4Very high92.9Very high104 Ų10456.4 Ų56.445%0.45228%0.28SS..THydrogen-bonded Turntrans-51-33.1-175.6-85.6170173.4165.20115.5E237 L239 N254 Y282E237-K256 IonicContact OE1-NZ 3.82Å; E237-K256 PolarHBondContact OE1-NZ 3.35Å; E237-K256 IonicContact OE2-NZ 3Å; E237-K256 PolarHBondContact OE2-NZ 2.75Å; L239-K256 HydrophobicContact CD2-CB 4.39Å; L239-K256 HydrophobicContact CD2-CD 4.34Å; N254-K256 VanDerWaalsContact OD1-CB 3.29Å; N254-K256 WeakPolarHBondContact OD1-CB 3.09Å; N254-K256 WeakPolarHBondContact OD1-CD 3.5Å; N254-K256 WeakPolarHBondContact OD1-CG 3.11Å; N254-K256 PolarHBondContact OD1-N 3.43Å; K256-Y282 HydrophobicContact CD-CE2 4.05Å
257I94.3Very high93.2Very high0 Ų056.4 Ų56.40%028%0.283CS..THydrogen-bonded Turntrans-1171-177.968.1167.6000112.6I230 L239 L240 D255 D259 D260 Y261 Y282 W285I230-I257 HydrophobicContact CG2-CD1 4.32Å; L239-I257 HydrophobicContact CB-CD1 3.69Å; L239-I257 HydrophobicContact CB-CG1 4.08Å; L239-I257 HydrophobicContact CD1-CD1 4.39Å; L239-I257 HydrophobicContact CD1-CG2 4.1Å; L240-I257 HydrophobicContact CB-CD1 4.03Å; D255-I257 PolarHBondContact O-N 3.37Å; I257-D259 PolarHBondContact O-N 2.8Å; I257-D260 PolarHBondContact O-N 2.89Å; I257-Y261 WeakPolarHBondContact O-CB 3.17Å; I257-Y261 PolarHBondContact O-N 3.29Å; I257-Y282 HydrophobicContact CG2-CD1 4.11Å; I257-Y282 HydrophobicContact CG2-CG 4.13Å; I257-W285 HydrophobicContact CB-CH2 3.78Å; I257-W285 HydrophobicContact CB-CZ2 3.74Å; I257-W285 HydrophobicContact CG2-CH2 4.44Å; I257-W285 HydrophobicContact CG2-CZ2 3.93Å
258R95.4Very high93.7Very high78 Ų7855.9 Ų55.929%0.29428%0.278SS..Hα-helixtrans-61.7-49.4-172.3176.7-178.5-70.3149.47.9111.2Y252 D255 D260 Y261 N262Y252-R258 HydrophobicContact CD1-CB 3.97Å; Y252-R258 HydrophobicContact CD1-CG 4.14Å; Y252-R258 HydrophobicContact CD2-CG 4.11Å; Y252-R258 HydrophobicContact CE1-CB 3.96Å; Y252-R258 HydrophobicContact CE1-CG 3.95Å; Y252-R258 HydrophobicContact CE2-CG 3.9Å; Y252-R258 HydrophobicContact CG-CB 4.4Å; Y252-R258 HydrophobicContact CG-CG 4.22Å; D255-R258 VanDerWaalsContact CG-NH1 3.26Å; D255-R258 PolarHBondContact O-N 2.94Å; D255-R258 IonicContact OD1-CZ 2.82Å; D255-R258 IonicContact OD1-NE 3.53Å; D255-R258 IonicContact OD1-NH1 2.86Å; D255-R258 PolarHBondContact OD1-NH1 3.2Å; D255-R258 IonicContact OD1-NH2 2.72Å; D255-R258 PolarHBondContact OD1-NH2 2.76Å; D255-R258 IonicContact OD2-NH1 3.9Å; D255-R258 PolarHBondContact OD2-NH1 2.7Å; R258-D260 VanDerWaalsContact C-N 3.26Å; R258-D260 PolarHBondContact O-N 3.27Å; R258-Y261 PolarHBondContact O-N 3.45Å; R258-N262 WeakPolarHBondContact O-CB 3.43Å; R258-N262 VanDerWaalsContact O-CG 3.3Å; R258-N262 PolarHBondContact O-N 2.83Å; R258-N262 PolarHBondContact O-ND2 2.89Å
259D95.9Very high93.6Very high110 Ų11057.7 Ų57.759%0.58830%0.298SS*.Hα-helixtrans-65.1-33.3-177.8-72.11.6000112I257 Y263 K308I257-D259 PolarHBondContact O-N 2.8Å; D259-Y263 WeakPolarHBondContact O-CB 3.14Å; D259-Y263 PolarHBondContact O-N 3.46Å; D259-K308 VanDerWaalsContact C-NZ 3.27Å; D259-K308 PolarHBondContact O-NZ 3.04Å
260D96Very high92.9Very high14 Ų1461.3 Ų61.38%0.07532%0.32CS..Hα-helixtrans-75.8-41.8178.6-60.5-41.7000111.1I257 R258 Y263 L264 W285 Y301 N303 K308I257-D260 PolarHBondContact O-N 2.89Å; R258-D260 VanDerWaalsContact C-N 3.26Å; R258-D260 PolarHBondContact O-N 3.27Å; D260-Y263 WeakPolarHBondContact O-CB 3.48Å; D260-Y263 PolarHBondContact O-N 3.23Å; D260-L264 WeakPolarHBondContact O-CG 3.2Å; D260-L264 PolarHBondContact O-N 2.9Å; D260-L264 VanDerWaalsContact O-N 3.16Å; D260-W285 HydrophobicContact CB-CH2 3.44Å; D260-W285 VanDerWaalsContact CB-CH2 3.44Å; D260-W285 HydrophobicContact CB-CZ2 3.41Å; D260-W285 VanDerWaalsContact CB-CZ2 3.41Å; D260-W285 HydrophobicContact CB-CZ3 4.35Å; D260-Y301 HydrophobicContact CB-CE1 3.97Å; D260-Y301 WeakPolarHBondContact CB-OH 3.43Å; D260-Y301 VanDerWaalsContact CG-OH 3.22Å; D260-Y301 PolarHBondContact OD1-OH 3.29Å; D260-N303 PolarHBondContact OD1-ND2 3.01Å; D260-K308 WeakPolarHBondContact OD1-CE 3.49Å; D260-K308 IonicContact OD1-NZ 3.4Å
261Y95.2Very high92.2Very high16 Ų1662.1 Ų62.16%0.06332%0.32CS..Hα-helixtrans-63.5-46.1175.1-168.1-78.1000111.2L240 V250 Y252 I257 R258 Y263 L264 V265 F273 I275 W285L240-Y261 HydrophobicContact CD1-CD1 4.48Å; L240-Y261 HydrophobicContact CD1-CD2 3.58Å; L240-Y261 HydrophobicContact CD1-CE2 3.67Å; L240-Y261 HydrophobicContact CD1-CG 4.03Å; V250-Y261 HydrophobicContact CG1-CE1 4.17Å; V250-Y261 HydrophobicContact CG1-CE2 4.39Å; V250-Y261 VanDerWaalsContact CG1-OH 3.25Å; V250-Y261 WeakPolarHBondContact CG1-OH 2.99Å; V250-Y261 HydrophobicContact CG2-CD1 4.39Å; V250-Y261 HydrophobicContact CG2-CE1 3.76Å; Y252-Y261 HydrophobicContact CE1-CD1 4.37Å; Y252-Y261 HydrophobicContact CE1-CG 4.27Å; Y252-Y261 WeakPolarHBondContact OH-CD1 3.2Å; I257-Y261 WeakPolarHBondContact O-CB 3.17Å; I257-Y261 PolarHBondContact O-N 3.29Å; R258-Y261 PolarHBondContact O-N 3.45Å; Y261-Y263 VanDerWaalsContact C-N 3.3Å; Y261-Y263 PolarHBondContact O-N 2.81Å; Y261-L264 WeakPolarHBondContact O-CB 3.32Å; Y261-L264 PolarHBondContact O-N 3.2Å; Y261-V265 HydrophobicContact CD1-CG2 3.72Å; Y261-V265 HydrophobicContact CE1-CG2 3.49Å; Y261-V265 VanDerWaalsContact CE1-CG2 3.49Å; Y261-V265 WeakPolarHBondContact O-CG2 3.45Å; Y261-V265 PolarHBondContact O-N 3.09Å; Y261-F273 HydrophobicContact CD1-CZ 4.16Å; Y261-F273 HydrophobicContact CD2-CE2 4.12Å; Y261-F273 HydrophobicContact CD2-CZ 4.11Å; Y261-F273 AromaticContact CE1-CZ 3.77Å; Y261-F273 HydrophobicContact CE1-CZ 3.77Å; Y261-F273 AromaticContact CE2-CE2 3.64Å; Y261-F273 HydrophobicContact CE2-CE2 3.64Å; Y261-F273 AromaticContact CE2-CZ 3.71Å; Y261-F273 HydrophobicContact CE2-CZ 3.71Å; Y261-F273 HydrophobicContact CG-CZ 4.31Å; Y261-F273 AromaticContact CZ-CE2 3.86Å; Y261-F273 AromaticContact CZ-CZ 3.51Å; Y261-I275 HydrophobicContact CD2-CD1 3.73Å; Y261-I275 HydrophobicContact CE2-CD1 3.85Å; Y261-W285 HydrophobicContact CD2-CZ3 4.35Å
262N94.5Very high91.7Very high60 Ų6064.2 Ų64.232%0.32133%0.327SS..Hα-helixtrans-60.5-39.3176.7-75-18.9000111.9Y252 R258 L264 V265 E266Y252-N262 PolarHBondContact OH-OD1 2.03Å; R258-N262 WeakPolarHBondContact O-CB 3.43Å; R258-N262 VanDerWaalsContact O-CG 3.3Å; R258-N262 PolarHBondContact O-N 2.83Å; R258-N262 PolarHBondContact O-ND2 2.89Å; N262-L264 VanDerWaalsContact C-N 3.28Å; N262-L264 PolarHBondContact O-N 3.34Å; N262-V265 WeakPolarHBondContact O-CB 3.49Å; N262-V265 PolarHBondContact O-N 3.03Å; N262-E266 WeakPolarHBondContact O-CG 3.21Å; N262-E266 PolarHBondContact O-N 3.12Å
263Y95.9Very high91.5Very high63 Ų6362.1 Ų62.125%0.24732%0.319CS..Hα-helixtrans-59-39.1173.3169.5-90000112.1D259 D260 Y261 E266 T267 Y301 K308 V310D259-Y263 WeakPolarHBondContact O-CB 3.14Å; D259-Y263 PolarHBondContact O-N 3.46Å; D260-Y263 WeakPolarHBondContact O-CB 3.48Å; D260-Y263 PolarHBondContact O-N 3.23Å; Y261-Y263 VanDerWaalsContact C-N 3.3Å; Y261-Y263 PolarHBondContact O-N 2.81Å; Y263-E266 PolarHBondContact O-N 3.44Å; Y263-T267 WeakPolarHBondContact CE1-OG1 3.29Å; Y263-T267 VanDerWaalsContact O-CB 3.31Å; Y263-T267 WeakPolarHBondContact O-CB 3.43Å; Y263-T267 PolarHBondContact O-N 3.4Å; Y263-T267 PolarHBondContact O-OG1 3.15Å; Y263-Y301 HydrophobicContact CD1-CD2 4.19Å; Y263-Y301 AromaticContact CD1-CE2 3.58Å; Y263-Y301 HydrophobicContact CD1-CE2 3.58Å; Y263-Y301 HydrophobicContact CE1-CD2 4.1Å; Y263-Y301 AromaticContact CE1-CE2 3.74Å; Y263-Y301 HydrophobicContact CE1-CE2 3.74Å; Y263-K308 HydrophobicContact CD1-CB 4.09Å; Y263-K308 HydrophobicContact CD1-CD 4.05Å; Y263-K308 HydrophobicContact CD2-CB 4.04Å; Y263-K308 HydrophobicContact CD2-CD 3.69Å; Y263-K308 HydrophobicContact CE1-CB 3.86Å; Y263-K308 HydrophobicContact CE2-CB 3.78Å; Y263-K308 HydrophobicContact CE2-CD 4.32Å; Y263-K308 HydrophobicContact CG-CB 4.19Å; Y263-K308 HydrophobicContact CG-CD 3.53Å; Y263-K308 HydrophobicContact CG-CG 4.47Å; Y263-V310 HydrophobicContact CE1-CG2 3.82Å
264L95.5Very high91.3Very high0 Ų060.3 Ų60.30%031%0.312CS..Hα-helixtrans-69.7-38.8176-64.6177.5000112.3D260 Y261 N262 E266 T267 F268 F273 W285 I287 Y301 V310D260-L264 WeakPolarHBondContact O-CG 3.2Å; D260-L264 PolarHBondContact O-N 2.9Å; D260-L264 VanDerWaalsContact O-N 3.16Å; Y261-L264 WeakPolarHBondContact O-CB 3.32Å; Y261-L264 PolarHBondContact O-N 3.2Å; N262-L264 VanDerWaalsContact C-N 3.28Å; N262-L264 PolarHBondContact O-N 3.34Å; L264-E266 VanDerWaalsContact C-N 3.32Å; L264-E266 PolarHBondContact O-N 3.25Å; L264-T267 PolarHBondContact O-N 3.2Å; L264-F268 HydrophobicContact CB-CD2 4.3Å; L264-F268 HydrophobicContact CB-CE2 4.39Å; L264-F268 HydrophobicContact CD2-CE2 3.91Å; L264-F268 VanDerWaalsContact O-CD2 3.3Å; L264-F268 WeakPolarHBondContact O-CD2 3.48Å; L264-F268 PolarHBondContact O-N 3.02Å; L264-F273 HydrophobicContact CB-CD1 4.47Å; L264-F273 HydrophobicContact CB-CE1 3.8Å; L264-F273 HydrophobicContact CB-CE2 3.98Å; L264-F273 HydrophobicContact CB-CZ 3.52Å; L264-F273 HydrophobicContact CD1-CD2 4.47Å; L264-F273 HydrophobicContact CD1-CE2 3.92Å; L264-F273 HydrophobicContact CD1-CZ 4.29Å; L264-W285 HydrophobicContact CD1-CE3 3.57Å; L264-W285 HydrophobicContact CD1-CZ3 3.71Å; L264-I287 HydrophobicContact CD1-CD1 3.67Å; L264-I287 HydrophobicContact CD1-CG1 4.02Å; L264-Y301 HydrophobicContact CD1-CG 4.48Å; L264-Y301 HydrophobicContact CD2-CD2 3.63Å; L264-Y301 HydrophobicContact CD2-CE2 4.29Å; L264-Y301 HydrophobicContact CD2-CG 4.01Å; L264-Y301 HydrophobicContact CG-CD2 4.35Å; L264-V310 HydrophobicContact CD2-CG2 3.92Å
265V93.1Very high91.3Very high65 Ų6559.7 Ų59.739%0.39431%0.308SS..Hα-helixtrans-58.3-46.2172.8173.80000110.6Y261 N262 G269 F273Y261-V265 HydrophobicContact CD1-CG2 3.72Å; Y261-V265 HydrophobicContact CE1-CG2 3.49Å; Y261-V265 VanDerWaalsContact CE1-CG2 3.49Å; Y261-V265 WeakPolarHBondContact O-CG2 3.45Å; Y261-V265 PolarHBondContact O-N 3.09Å; N262-V265 WeakPolarHBondContact O-CB 3.49Å; N262-V265 PolarHBondContact O-N 3.03Å; V265-G269 WeakPolarHBondContact O-CA 3.34Å; V265-G269 PolarHBondContact O-N 2.79Å; V265-F273 HydrophobicContact CG2-CE1 3.84Å; V265-F273 HydrophobicContact CG2-CZ 4.09Å
266E93.9Very high91.2Very high157 Ų15759.3 Ų59.373%0.73430%0.303SS*.Hα-helixtrans-65.8-38.7176.5-70.6172.6-172.600112.3N262 Y263 L264N262-E266 WeakPolarHBondContact O-CG 3.21Å; N262-E266 PolarHBondContact O-N 3.12Å; Y263-E266 PolarHBondContact O-N 3.44Å; L264-E266 VanDerWaalsContact C-N 3.32Å; L264-E266 PolarHBondContact O-N 3.25Å
267T94.7Very high91Very high61 Ų6157.8 Ų57.837%0.37431%0.306SS..Hα-helixtrans-68.4-42.9-178-610000112.3Y263 L264 V310Y263-T267 WeakPolarHBondContact CE1-OG1 3.29Å; Y263-T267 VanDerWaalsContact O-CB 3.31Å; Y263-T267 WeakPolarHBondContact O-CB 3.43Å; Y263-T267 PolarHBondContact O-N 3.4Å; Y263-T267 PolarHBondContact O-OG1 3.15Å; L264-T267 PolarHBondContact O-N 3.2Å; T267-V310 HydrophobicContact CG2-CG2 4.11Å
268F92.1Very high90.9Very high27 Ų2759.5 Ų59.512%0.11832%0.315CS..Hα-helixtrans-95.8-16.1-175.6-62.3-53.9000113.4L264 L270 E271 F273 I287 V289 Y299 V310L264-F268 HydrophobicContact CB-CD2 4.3Å; L264-F268 HydrophobicContact CB-CE2 4.39Å; L264-F268 HydrophobicContact CD2-CE2 3.91Å; L264-F268 VanDerWaalsContact O-CD2 3.3Å; L264-F268 WeakPolarHBondContact O-CD2 3.48Å; L264-F268 PolarHBondContact O-N 3.02Å; F268-L270 PolarHBondContact O-N 2.94Å; F268-L270 VanDerWaalsContact O-N 3.12Å; F268-E271 HydrophobicContact CB-CB 4.22Å; F268-E271 WeakPolarHBondContact O-CB 3.49Å; F268-E271 PolarHBondContact O-N 3.18Å; F268-F273 HydrophobicContact CD2-CB 4.25Å; F268-F273 AromaticContact CD2-CD1 3.89Å; F268-F273 HydrophobicContact CD2-CD1 3.89Å; F268-F273 HydrophobicContact CD2-CG 4.16Å; F268-I287 HydrophobicContact CE2-CG2 4Å; F268-V289 HydrophobicContact CD1-CG1 4.25Å; F268-V289 HydrophobicContact CD1-CG2 3.74Å; F268-V289 HydrophobicContact CD2-CG2 3.89Å; F268-V289 HydrophobicContact CE1-CG2 3.5Å; F268-V289 HydrophobicContact CE2-CG2 3.63Å; F268-V289 HydrophobicContact CG-CG1 4.44Å; F268-V289 HydrophobicContact CG-CG2 3.93Å; F268-V289 HydrophobicContact CZ-CG2 3.42Å; F268-V289 VanDerWaalsContact CZ-CG2 3.42Å; F268-Y299 HydrophobicContact CE1-CD1 4.45Å; F268-Y299 HydrophobicContact CE1-CD2 4.19Å; F268-Y299 HydrophobicContact CE1-CE1 4.38Å; F268-Y299 HydrophobicContact CE1-CE2 4.12Å; F268-Y299 HydrophobicContact CE1-CG 4.35Å; F268-Y299 HydrophobicContact CZ-CD1 4.47Å; F268-Y299 HydrophobicContact CZ-CD2 4.08Å; F268-Y299 HydrophobicContact CZ-CE2 4.47Å; F268-Y299 HydrophobicContact CZ-CG 4.08Å; F268-V310 HydrophobicContact CE1-CG1 4.27Å; F268-V310 HydrophobicContact CZ-CG1 3.71Å
269G84.5Confident90.7Very high50 Ų5057.1 Ų57.152%0.51531%0.31SS..THydrogen-bonded Turntrans59.5-112.917200000112.9V265 E271V265-G269 WeakPolarHBondContact O-CA 3.34Å; V265-G269 PolarHBondContact O-N 2.79Å; G269-E271 VanDerWaalsContact C-N 3.34Å
270L72.1Confident90.3Very high169 Ų16956.3 Ų56.389%0.88530%0.303SS*.THydrogen-bonded Turntrans-79-16.9-179.8-63.4178.9000113.4F268F268-L270 PolarHBondContact O-N 2.94Å; F268-L270 VanDerWaalsContact O-N 3.12Å
271E76.9Confident90Very high61 Ų6161.8 Ų61.829%0.28533%0.328SS..SBendtrans-69138.4170.6-61.4-71.5138.900108.9F268 G269 V289 N291 N294F268-E271 HydrophobicContact CB-CB 4.22Å; F268-E271 WeakPolarHBondContact O-CB 3.49Å; F268-E271 PolarHBondContact O-N 3.18Å; G269-E271 VanDerWaalsContact C-N 3.34Å; E271-V289 HydrophobicContact CB-CG1 3.61Å; E271-V289 HydrophobicContact CG-CG1 4.22Å; E271-N291 PolarHBondContact OE1-ND2 2.74Å; E271-N291 PolarHBondContact OE2-ND2 2.83Å; E271-N294 PolarHBondContact OE2-ND2 2.88Å; E271-N294 VanDerWaalsContact OE2-ND2 3.12Å
272K83.6Confident89.9Confident56 Ų5662.7 Ų62.724%0.24333%0.331CS..EExtended strand (participates in β ladder)trans-88.6154.5173.5-65.8-67.9-178.5166.50108.8T247 S248 V289 F290 W376T247-K272 PolarHBondContact OG1-NZ 2.99Å; S248-K272 PolarHBondContact O-NZ 2.77Å; K272-V289 CarbonylContact O-C 3.59Å; K272-V289 WeakPolarHBondContact O-CA 3.34Å; K272-F290 CarbonylContact C-O 3.55Å; K272-F290 PolarHBondContact N-O 2.84Å; K272-F290 PolarHBondContact O-N 2.82Å; K272-W376 HydrophobicContact CG-CE3 4.46Å; K272-W376 HydrophobicContact CG-CZ3 3.97Å
273F91.8Very high89.8Confident13 Ų1362.3 Ų62.36%0.05733%0.329CS..EExtended strand (participates in β ladder)trans-138.9150.8174.970.5-90.4000110.9Y261 L264 V265 F268 I275 I287 M288 V289Y261-F273 HydrophobicContact CD1-CZ 4.16Å; Y261-F273 HydrophobicContact CD2-CE2 4.12Å; Y261-F273 HydrophobicContact CD2-CZ 4.11Å; Y261-F273 AromaticContact CE1-CZ 3.77Å; Y261-F273 HydrophobicContact CE1-CZ 3.77Å; Y261-F273 AromaticContact CE2-CE2 3.64Å; Y261-F273 HydrophobicContact CE2-CE2 3.64Å; Y261-F273 AromaticContact CE2-CZ 3.71Å; Y261-F273 HydrophobicContact CE2-CZ 3.71Å; Y261-F273 HydrophobicContact CG-CZ 4.31Å; Y261-F273 AromaticContact CZ-CE2 3.86Å; Y261-F273 AromaticContact CZ-CZ 3.51Å; L264-F273 HydrophobicContact CB-CD1 4.47Å; L264-F273 HydrophobicContact CB-CE1 3.8Å; L264-F273 HydrophobicContact CB-CE2 3.98Å; L264-F273 HydrophobicContact CB-CZ 3.52Å; L264-F273 HydrophobicContact CD1-CD2 4.47Å; L264-F273 HydrophobicContact CD1-CE2 3.92Å; L264-F273 HydrophobicContact CD1-CZ 4.29Å; V265-F273 HydrophobicContact CG2-CE1 3.84Å; V265-F273 HydrophobicContact CG2-CZ 4.09Å; F268-F273 HydrophobicContact CD2-CB 4.25Å; F268-F273 AromaticContact CD2-CD1 3.89Å; F268-F273 HydrophobicContact CD2-CD1 3.89Å; F268-F273 HydrophobicContact CD2-CG 4.16Å; F273-I275 HydrophobicContact CD2-CG1 4.45Å; F273-I275 HydrophobicContact CE2-CD1 4.5Å; F273-I275 HydrophobicContact CE2-CG1 4.23Å; F273-I287 HydrophobicContact CB-CG2 3.68Å; F273-I287 HydrophobicContact CD2-CG2 3.81Å; F273-I287 HydrophobicContact CG-CG2 4.04Å; F273-M288 CarbonylContact C-O 3.57Å; F273-M288 WeakPolarHBondContact CA-O 3.27Å; F273-V289 HydrophobicContact CB-CG2 4.11Å
274S90.7Very high89.7Confident24 Ų2465.7 Ų65.717%0.16834%0.342CS..EExtended strand (participates in β ladder)trans-119.6141.8169.9560000109.5Q276 M288 F290S274-Q276 PolarHBondContact O-N 3Å; S274-Q276 PolarHBondContact OG-NE2 3.24Å; S274-M288 PolarHBondContact N-O 3.46Å; S274-M288 PolarHBondContact O-N 2.87Å; S274-F290 WeakPolarHBondContact OG-CE1 3.26Å
275I93.4Very high89.7Confident24 Ų2465.7 Ų65.712%0.12334%0.342CS..EExtended strand (participates in β ladder)trans-84.1113.4174.7-66.1169.5000107.5I230 Y261 F273 I278 W285 I287I230-I275 HydrophobicContact CD1-CB 4.04Å; I230-I275 HydrophobicContact CD1-CD1 3.46Å; I230-I275 VanDerWaalsContact CD1-CD1 3.46Å; I230-I275 HydrophobicContact CD1-CG1 4.27Å; I230-I275 HydrophobicContact CD1-CG2 4.33Å; Y261-I275 HydrophobicContact CD2-CD1 3.73Å; Y261-I275 HydrophobicContact CE2-CD1 3.85Å; F273-I275 HydrophobicContact CD2-CG1 4.45Å; F273-I275 HydrophobicContact CE2-CD1 4.5Å; F273-I275 HydrophobicContact CE2-CG1 4.23Å; I275-I278 HydrophobicContact CD1-CD1 4.42Å; I275-I278 HydrophobicContact CG2-CD1 3.7Å; I275-I278 HydrophobicContact CG2-CG1 3.42Å; I275-I278 VanDerWaalsContact CG2-CG1 3.42Å; I275-W285 HydrophobicContact CD1-CE3 3.67Å; I275-W285 HydrophobicContact CD1-CZ3 3.61Å; I275-W285 HydrophobicContact CG1-CE3 4.08Å; I275-W285 HydrophobicContact CG1-CZ3 4.45Å; I275-I287 HydrophobicContact CB-CD1 4.4Å; I275-I287 HydrophobicContact CG1-CD1 3.74Å
276Q91.9Very high89.8Confident93 Ų9365.2 Ų65.244%0.43534%0.336SS..EExtended strand (participates in β ladder)trans-82.5-34.7179.8-58.9-62.9-51.900111.4S274 L286 M288S274-Q276 PolarHBondContact O-N 3Å; S274-Q276 PolarHBondContact OG-NE2 3.24Å; Q276-L286 HydrophobicContact CB-CB 4.11Å; Q276-L286 HydrophobicContact CB-CD2 3.95Å; Q276-L286 HydrophobicContact CB-CG 3.98Å; Q276-L286 WeakPolarHBondContact CB-O 3.42Å; Q276-L286 HydrophobicContact CG-CG 4.5Å; Q276-L286 PolarHBondContact N-O 2.85Å; Q276-M288 HydrophobicContact CG-CB 3.8Å
277S90.4Very high89.9Confident72 Ų7257.7 Ų57.750%0.50330%0.301SS..EExtended strand (participates in β ladder)trans-162.7151.2177.9-170.40000111.4W285 L286S277-W285 CarbonylContact O-C 3.41Å; S277-W285 VanDerWaalsContact O-CA 3.28Å; S277-W285 WeakPolarHBondContact O-CA 3.28Å; S277-L286 PolarHBondContact N-O 2.05Å; S277-L286 PolarHBondContact O-N 2.84Å
278I91.9Very high90Very high37 Ų3756.8 Ų56.819%0.1929%0.293CS..EExtended strand (participates in β ladder)trans-130.3132.7174.1-61.6165.1000109.7I230 I275 Y282 W285I230-I278 HydrophobicContact CD1-CD1 4.38Å; I230-I278 HydrophobicContact CG2-CD1 3.55Å; I275-I278 HydrophobicContact CD1-CD1 4.42Å; I275-I278 HydrophobicContact CG2-CD1 3.7Å; I275-I278 HydrophobicContact CG2-CG1 3.42Å; I275-I278 VanDerWaalsContact CG2-CG1 3.42Å; I278-Y282 HydrophobicContact CG2-CD1 3.71Å; I278-W285 HydrophobicContact CD1-CD2 4.49Å; I278-W285 HydrophobicContact CG1-CB 4.33Å; I278-W285 HydrophobicContact CG1-CD2 4.08Å; I278-W285 HydrophobicContact CG1-CG 3.88Å; I278-W285 HydrophobicContact CG2-CG 4.34Å
279S90.9Very high90.1Very high27 Ų2755.6 Ų55.619%0.18929%0.288CS..  trans-61.7153.8170.162.40000112.5Q281 Y282 N283 R284S279-Q281 PolarHBondContact O-N 2.75Å; S279-Q281 VanDerWaalsContact O-N 3.13Å; S279-Y282 WeakPolarHBondContact O-CA 3.34Å; S279-Y282 PolarHBondContact O-N 3.14Å; S279-Y282 PolarHBondContact OG-N 3.07Å; S279-N283 PolarHBondContact OG-N 2.8Å; S279-N283 VanDerWaalsContact OG-N 3.16Å; S279-N283 PolarHBondContact OG-OD1 2.97Å; S279-R284 WeakPolarHBondContact CB-O 3.3Å; S279-R284 PolarHBondContact N-O 2.86Å; S279-R284 PolarHBondContact OG-N 3.4Å; S279-R284 PolarHBondContact OG-O 2.97Å
280Q86.5Confident90.5Very high93 Ų9354.7 Ų54.744%0.43527%0.27SS..THydrogen-bonded Turntrans-54.8-34176.8-68-179300114.6Y234 Y282Y234-Q280 HydrophobicContact CD2-CG 4.39Å; Y234-Q280 HydrophobicContact CE2-CG 3.58Å; Y234-Q280 PolarHBondContact OH-NE2 3.16Å; Q280-Y282 PolarHBondContact O-N 3.18Å
281Q90.1Very high91.4Very high130 Ų13046.8 Ų46.861%0.60723%0.229SC*.THydrogen-bonded Turntrans-833.7178.8-59.479.61500112.9S279 N283S279-Q281 PolarHBondContact O-N 2.75Å; S279-Q281 VanDerWaalsContact O-N 3.13Å; Q281-N283 PolarHBondContact O-N 2.84Å; Q281-N283 VanDerWaalsContact O-N 3.08Å
282Y93.1Very high92Very high35 Ų3544 Ų4414%0.13722%0.216CC..SBendtrans55.920.5-176.7-47.2-62.2000115N232 L239 K256 I257 I278 S279 Q280 W285N232-Y282 WeakPolarHBondContact CB-OH 3.36Å; N232-Y282 PolarHBondContact ND2-OH 3.35Å; L239-Y282 HydrophobicContact CD1-CD1 4.09Å; L239-Y282 HydrophobicContact CD1-CE1 3.47Å; L239-Y282 VanDerWaalsContact CD1-CE1 3.47Å; K256-Y282 HydrophobicContact CD-CE2 4.05Å; I257-Y282 HydrophobicContact CG2-CD1 4.11Å; I257-Y282 HydrophobicContact CG2-CG 4.13Å; I278-Y282 HydrophobicContact CG2-CD1 3.71Å; S279-Y282 WeakPolarHBondContact O-CA 3.34Å; S279-Y282 PolarHBondContact O-N 3.14Å; S279-Y282 PolarHBondContact OG-N 3.07Å; Q280-Y282 PolarHBondContact O-N 3.18Å; Y282-W285 PolarHBondContact O-NE1 2.86Å
283N93.4Very high92.5Very high51 Ų5142.9 Ų42.927%0.27321%0.214SC..  trans-112-0.8-172.177.8-26.6000113.5S279 Q281 L302 N303S279-N283 PolarHBondContact OG-N 2.8Å; S279-N283 VanDerWaalsContact OG-N 3.16Å; S279-N283 PolarHBondContact OG-OD1 2.97Å; Q281-N283 PolarHBondContact O-N 2.84Å; Q281-N283 VanDerWaalsContact O-N 3.08Å; N283-L302 CarbonylContact O-C 3.48Å; N283-L302 WeakPolarHBondContact O-CA 3.39Å; N283-N303 HydrophobicContact CB-CB 4.33Å; N283-N303 WeakPolarHBondContact CB-O 3.34Å; N283-N303 PolarHBondContact O-N 2.82Å
284R94Very high92.5Very high135 Ų13543 Ų4351%0.50922%0.215SC..EExtended strand (participates in β ladder)trans-138.2118.5172.4-52.1-172.2179-175.6-2.4111.1S279 Y301 L302S279-R284 WeakPolarHBondContact CB-O 3.3Å; S279-R284 PolarHBondContact N-O 2.86Å; S279-R284 PolarHBondContact OG-N 3.4Å; S279-R284 PolarHBondContact OG-O 2.97Å; R284-Y301 CarbonylContact C-O 3.57Å; R284-Y301 VanDerWaalsContact CA-O 3.28Å; R284-Y301 WeakPolarHBondContact CA-O 3.28Å; R284-L302 HydrophobicContact CB-CD2 4.04Å; R284-L302 HydrophobicContact CG-CD2 3.61Å
285W95.4Very high92.5Very high0 Ų043 Ų430%022%0.217CC..EExtended strand (participates in β ladder)trans-124.1136.7-177.7-47.3-1.4000109.7I257 D260 Y261 L264 I275 S277 I278 Y282 I287 Y301I257-W285 HydrophobicContact CB-CH2 3.78Å; I257-W285 HydrophobicContact CB-CZ2 3.74Å; I257-W285 HydrophobicContact CG2-CH2 4.44Å; I257-W285 HydrophobicContact CG2-CZ2 3.93Å; D260-W285 HydrophobicContact CB-CH2 3.44Å; D260-W285 VanDerWaalsContact CB-CH2 3.44Å; D260-W285 HydrophobicContact CB-CZ2 3.41Å; D260-W285 VanDerWaalsContact CB-CZ2 3.41Å; D260-W285 HydrophobicContact CB-CZ3 4.35Å; Y261-W285 HydrophobicContact CD2-CZ3 4.35Å; L264-W285 HydrophobicContact CD1-CE3 3.57Å; L264-W285 HydrophobicContact CD1-CZ3 3.71Å; I275-W285 HydrophobicContact CD1-CE3 3.67Å; I275-W285 HydrophobicContact CD1-CZ3 3.61Å; I275-W285 HydrophobicContact CG1-CE3 4.08Å; I275-W285 HydrophobicContact CG1-CZ3 4.45Å; S277-W285 CarbonylContact O-C 3.41Å; S277-W285 VanDerWaalsContact O-CA 3.28Å; S277-W285 WeakPolarHBondContact O-CA 3.28Å; I278-W285 HydrophobicContact CD1-CD2 4.49Å; I278-W285 HydrophobicContact CG1-CB 4.33Å; I278-W285 HydrophobicContact CG1-CD2 4.08Å; I278-W285 HydrophobicContact CG1-CG 3.88Å; I278-W285 HydrophobicContact CG2-CG 4.34Å; Y282-W285 PolarHBondContact O-NE1 2.86Å; W285-I287 HydrophobicContact CB-CD1 3.71Å; W285-I287 HydrophobicContact CB-CG1 4.29Å; W285-I287 HydrophobicContact CE3-CD1 4Å; W285-Y301 HydrophobicContact CB-CD1 4.01Å; W285-Y301 AromaticContact CD1-CD1 3.92Å; W285-Y301 AromaticContact CD2-CD1 3.73Å; W285-Y301 HydrophobicContact CD2-CD1 3.73Å; W285-Y301 HydrophobicContact CD2-CE1 4.13Å; W285-Y301 HydrophobicContact CE3-CD1 4.28Å; W285-Y301 AromaticContact CG-CD1 3.62Å; W285-Y301 HydrophobicContact CG-CD1 3.62Å; W285-Y301 HydrophobicContact CG-CE1 4.32Å; W285-Y301 HydrophobicContact CZ2-CE1 4.46Å; W285-Y301 PolarHBondContact N-O 3.35Å; W285-Y301 PolarHBondContact O-N 3.19Å
286L94.9Very high92.6Very high54 Ų5441.9 Ų41.928%0.28321%0.211SC..EExtended strand (participates in β ladder)trans-89121.3167.1-172.767.2000107.8Q276 S277 L298 L313Q276-L286 HydrophobicContact CB-CB 4.11Å; Q276-L286 HydrophobicContact CB-CD2 3.95Å; Q276-L286 HydrophobicContact CB-CG 3.98Å; Q276-L286 WeakPolarHBondContact CB-O 3.42Å; Q276-L286 HydrophobicContact CG-CG 4.5Å; Q276-L286 PolarHBondContact N-O 2.85Å; S277-L286 PolarHBondContact N-O 2.05Å; S277-L286 PolarHBondContact O-N 2.84Å; L286-L298 HydrophobicContact CD1-CD2 4.12Å; L286-L298 HydrophobicContact CD2-CD2 4.23Å; L286-L298 HydrophobicContact CG-CD2 4.32Å; L286-L313 HydrophobicContact CD1-CD1 3.66Å
287I96.2Very high92.8Very high0 Ų039 Ų390%020%0.198CC..EExtended strand (participates in β ladder)trans-117.9134.3-174.6-51.6-60000108.9L264 F268 F273 I275 W285 V289 L298 Y299L264-I287 HydrophobicContact CD1-CD1 3.67Å; L264-I287 HydrophobicContact CD1-CG1 4.02Å; F268-I287 HydrophobicContact CE2-CG2 4Å; F273-I287 HydrophobicContact CB-CG2 3.68Å; F273-I287 HydrophobicContact CD2-CG2 3.81Å; F273-I287 HydrophobicContact CG-CG2 4.04Å; I275-I287 HydrophobicContact CB-CD1 4.4Å; I275-I287 HydrophobicContact CG1-CD1 3.74Å; W285-I287 HydrophobicContact CB-CD1 3.71Å; W285-I287 HydrophobicContact CB-CG1 4.29Å; W285-I287 HydrophobicContact CE3-CD1 4Å; I287-V289 HydrophobicContact CG2-CG2 4.16Å; I287-L298 CarbonylContact O-C 3.58Å; I287-L298 WeakPolarHBondContact O-CA 3.24Å; I287-Y299 PolarHBondContact N-O 3.44Å; I287-Y299 PolarHBondContact O-N 2.89Å
288M95.3Very high93Very high41 Ų4136.2 Ų36.220%0.20218%0.177CC..EExtended strand (participates in β ladder)trans-107.1120.4166.2-176-179.9-65.900108.5F273 S274 Q276 F290 M297 L298 I316F273-M288 CarbonylContact C-O 3.57Å; F273-M288 WeakPolarHBondContact CA-O 3.27Å; S274-M288 PolarHBondContact N-O 3.46Å; S274-M288 PolarHBondContact O-N 2.87Å; Q276-M288 HydrophobicContact CG-CB 3.8Å; M288-F290 HydrophobicContact CG-CD1 4.37Å; M288-M297 CarbonylContact C-O 3.49Å; M288-M297 WeakPolarHBondContact CA-O 3.36Å; M288-L298 HydrophobicContact CE-CD1 4.01Å; M288-I316 HydrophobicContact CE-CD1 4.03Å; M288-I316 HydrophobicContact SD-CD1 4.4Å
289V95.2Very high93.2Very high3 Ų336.6 Ų36.62%0.01818%0.176CC..EExtended strand (participates in β ladder)trans-99.1126.3175.2-178.80000108.1F268 E271 K272 F273 I287 N294 G296 M297 Y299F268-V289 HydrophobicContact CD1-CG1 4.25Å; F268-V289 HydrophobicContact CD1-CG2 3.74Å; F268-V289 HydrophobicContact CD2-CG2 3.89Å; F268-V289 HydrophobicContact CE1-CG2 3.5Å; F268-V289 HydrophobicContact CE2-CG2 3.63Å; F268-V289 HydrophobicContact CG-CG1 4.44Å; F268-V289 HydrophobicContact CG-CG2 3.93Å; F268-V289 HydrophobicContact CZ-CG2 3.42Å; F268-V289 VanDerWaalsContact CZ-CG2 3.42Å; E271-V289 HydrophobicContact CB-CG1 3.61Å; E271-V289 HydrophobicContact CG-CG1 4.22Å; K272-V289 CarbonylContact O-C 3.59Å; K272-V289 WeakPolarHBondContact O-CA 3.34Å; F273-V289 HydrophobicContact CB-CG2 4.11Å; I287-V289 HydrophobicContact CG2-CG2 4.16Å; V289-N294 PolarHBondContact O-ND2 2.96Å; V289-G296 CarbonylContact O-C 3.55Å; V289-G296 VanDerWaalsContact O-CA 3.31Å; V289-G296 WeakPolarHBondContact O-CA 3.21Å; V289-M297 PolarHBondContact N-O 3.14Å; V289-M297 PolarHBondContact O-N 2.91Å; V289-Y299 HydrophobicContact CB-CD2 4.15Å; V289-Y299 HydrophobicContact CB-CE2 3.89Å; V289-Y299 HydrophobicContact CG2-CD2 3.5Å; V289-Y299 HydrophobicContact CG2-CE2 3.6Å
290F92.3Very high93.4Very high31 Ų3136.1 Ų36.114%0.13617%0.172CC..EExtended strand (participates in β ladder)trans-151.5161.2-175.366.6-82000110.6K272 S274 M288 E377K272-F290 CarbonylContact C-O 3.55Å; K272-F290 PolarHBondContact N-O 2.84Å; K272-F290 PolarHBondContact O-N 2.82Å; S274-F290 WeakPolarHBondContact OG-CE1 3.26Å; M288-F290 HydrophobicContact CG-CD1 4.37Å; F290-E377 HydrophobicContact CD2-CB 4.25Å; F290-E377 HydrophobicContact CE2-CB 4.26Å
291N91Very high93.9Very high2 Ų231.7 Ų31.71%0.01115%0.151CC..EExtended strand (participates in β ladder)trans-158.6-166.7167.566.722.1000109.2E271 V293 N294 R327 W376 Y378E271-N291 PolarHBondContact OE1-ND2 2.74Å; E271-N291 PolarHBondContact OE2-ND2 2.83Å; N291-V293 PolarHBondContact O-N 2.91Å; N291-V293 VanDerWaalsContact OD1-C 3.24Å; N291-V293 WeakPolarHBondContact OD1-CA 3.49Å; N291-V293 WeakPolarHBondContact OD1-CG2 3.39Å; N291-V293 PolarHBondContact OD1-N 3.38Å; N291-N294 PolarHBondContact N-O 3.23Å; N291-N294 PolarHBondContact O-N 2.9Å; N291-N294 VanDerWaalsContact O-O 3.09Å; N291-N294 WeakPolarHBondContact OD1-CB 3.5Å; N291-N294 PolarHBondContact OD1-N 2.54Å; N291-R327 PolarHBondContact ND2-NH1 2.9Å; N291-W376 HydrophobicContact CB-CH2 3.64Å; N291-W376 HydrophobicContact CB-CZ3 3.67Å; N291-Y378 WeakPolarHBondContact O-CB 3.27Å; N291-Y378 PolarHBondContact O-N 2.87Å
292D91Very high94.2Very high3 Ų325.7 Ų25.72%0.01612%0.123CC..THydrogen-bonded Turntrans-58.6-25.217761.4-27.3000115.6R327 R328 W376 Q383D292-R327 IonicContact OD1-CZ 2.74Å; D292-R327 IonicContact OD1-NH1 3.86Å; D292-R327 PolarHBondContact OD1-NH1 3.42Å; D292-R327 WeakPolarHBondContact OD2-CA 3.16Å; D292-R327 WeakPolarHBondContact OD2-CD 3.33Å; D292-R328 HydrophobicContact CB-CB 3.53Å; D292-R328 PolarHBondContact OD2-N 2.93Å; D292-W376 HydrophobicContact CB-CZ2 3.82Å; D292-W376 WeakPolarHBondContact OD1-CZ2 3.43Å; D292-Q383 PolarHBondContact O-NE2 3.45Å
293V92.4Very high94.3Very high33 Ų3325.3 Ų25.320%0.212%0.123CC..THydrogen-bonded Turntrans-123.314.1-178.1-63.90000113.1N291 L325 A326 R327N291-V293 PolarHBondContact O-N 2.91Å; N291-V293 VanDerWaalsContact OD1-C 3.24Å; N291-V293 WeakPolarHBondContact OD1-CA 3.49Å; N291-V293 WeakPolarHBondContact OD1-CG2 3.39Å; N291-V293 PolarHBondContact OD1-N 3.38Å; V293-L325 HydrophobicContact CB-CB 3.8Å; V293-L325 HydrophobicContact CG1-CB 3.78Å; V293-L325 WeakPolarHBondContact O-CD1 3.46Å; V293-A326 WeakPolarHBondContact CG1-O 3.27Å; V293-R327 HydrophobicContact CG1-CG 4.16Å
294N91.7Very high94.2Very high16 Ų1625 Ų259%0.08613%0.125CC..EExtended strand (participates in β ladder)trans-133104.3178.9176.54.2000107.2E271 V289 N291 G296E271-N294 PolarHBondContact OE2-ND2 2.88Å; E271-N294 VanDerWaalsContact OE2-ND2 3.12Å; V289-N294 PolarHBondContact O-ND2 2.96Å; N291-N294 PolarHBondContact N-O 3.23Å; N291-N294 PolarHBondContact O-N 2.9Å; N291-N294 VanDerWaalsContact O-O 3.09Å; N291-N294 WeakPolarHBondContact OD1-CB 3.5Å; N291-N294 PolarHBondContact OD1-N 2.54Å; N294-G296 PolarHBondContact O-N 3.23Å; N294-G296 PolarHBondContact OD1-N 2.9Å; N294-G296 VanDerWaalsContact OD1-N 3.13Å
295A92.6Very high94Very high24 Ų2427.7 Ų27.720%0.19814%0.144CC..EExtended strand (participates in β ladder)trans-62.3-11.8-177.500000114.1L320 Y378A295-L320 HydrophobicContact CB-CD1 3.91Å; A295-Y378 HydrophobicContact CB-CD1 3.66Å; A295-Y378 HydrophobicContact CB-CD2 4.05Å; A295-Y378 HydrophobicContact CB-CE1 3.77Å; A295-Y378 HydrophobicContact CB-CE2 4.12Å; A295-Y378 HydrophobicContact CB-CG 3.83Å
296G94.4Very high93.7Very high0 Ų030.4 Ų30.40%017%0.172CC..EExtended strand (participates in β ladder)trans128.5130.7177.100000111.1V289 N294 I316V289-G296 CarbonylContact O-C 3.55Å; V289-G296 VanDerWaalsContact O-CA 3.31Å; V289-G296 WeakPolarHBondContact O-CA 3.21Å; N294-G296 PolarHBondContact O-N 3.23Å; N294-G296 PolarHBondContact OD1-N 2.9Å; N294-G296 VanDerWaalsContact OD1-N 3.13Å; G296-I316 WeakPolarHBondContact O-CB 3.43Å; G296-I316 WeakPolarHBondContact O-CG1 3.33Å; G296-I316 PolarHBondContact O-N 2.77Å
297M95.6Very high93.7Very high33 Ų3336.9 Ų36.916%0.16319%0.192CC..EExtended strand (participates in β ladder)trans-126.2127.6172.6-67.3177.9-17600108.5M288 V289 Y299 F312 A315 L321M288-M297 CarbonylContact C-O 3.49Å; M288-M297 WeakPolarHBondContact CA-O 3.36Å; V289-M297 PolarHBondContact N-O 3.14Å; V289-M297 PolarHBondContact O-N 2.91Å; M297-Y299 HydrophobicContact CB-CD2 4.25Å; M297-Y299 HydrophobicContact CB-CE2 3.51Å; M297-Y299 WeakPolarHBondContact O-CD2 3.26Å; M297-Y299 HydrophobicContact SD-CE2 4.43Å; M297-F312 HydrophobicContact CB-CE2 4.32Å; M297-F312 HydrophobicContact CG-CE2 4.4Å; M297-A315 HydrophobicContact CG-CB 4.04Å; M297-L321 HydrophobicContact CE-CD1 4.35Å; M297-L321 HydrophobicContact CE-CD2 3.32Å; M297-L321 HydrophobicContact CE-CG 4.47Å
298L95.5Very high93.6Very high13 Ų1339.8 Ų39.87%0.06821%0.205CC..EExtended strand (participates in β ladder)trans-89.9137.1176.7-80.183.7000110.9L286 I287 M288 L313 Y314 I316L286-L298 HydrophobicContact CD1-CD2 4.12Å; L286-L298 HydrophobicContact CD2-CD2 4.23Å; L286-L298 HydrophobicContact CG-CD2 4.32Å; I287-L298 CarbonylContact O-C 3.58Å; I287-L298 WeakPolarHBondContact O-CA 3.24Å; M288-L298 HydrophobicContact CE-CD1 4.01Å; L298-L313 HydrophobicContact CB-CB 4.21Å; L298-L313 HydrophobicContact CB-CD1 4.4Å; L298-L313 WeakPolarHBondContact O-CA 3.45Å; L298-L313 WeakPolarHBondContact O-CB 3.29Å; L298-L313 PolarHBondContact O-N 3.17Å; L298-Y314 HydrophobicContact CB-CD1 4.25Å; L298-Y314 HydrophobicContact CB-CE1 3.96Å; L298-Y314 HydrophobicContact CD1-CE1 4.07Å; L298-Y314 HydrophobicContact CD1-CE2 3.84Å; L298-Y314 WeakPolarHBondContact CD1-OH 3.16Å; L298-Y314 HydrophobicContact CD2-CE1 3.89Å; L298-Y314 HydrophobicContact CG-CE1 4.18Å; L298-Y314 PolarHBondContact N-O 3.15Å; L298-I316 HydrophobicContact CD1-CD1 4.09Å; L298-I316 HydrophobicContact CD1-CG1 4.1Å
299Y96Very high93.6Very high44 Ų4440.6 Ų40.617%0.17321%0.209CC..EExtended strand (participates in β ladder)trans-131.1149.1175.7-65.5-95.9000110.4F268 I287 V289 M297 V310 I311 F312F268-Y299 HydrophobicContact CE1-CD1 4.45Å; F268-Y299 HydrophobicContact CE1-CD2 4.19Å; F268-Y299 HydrophobicContact CE1-CE1 4.38Å; F268-Y299 HydrophobicContact CE1-CE2 4.12Å; F268-Y299 HydrophobicContact CE1-CG 4.35Å; F268-Y299 HydrophobicContact CZ-CD1 4.47Å; F268-Y299 HydrophobicContact CZ-CD2 4.08Å; F268-Y299 HydrophobicContact CZ-CE2 4.47Å; F268-Y299 HydrophobicContact CZ-CG 4.08Å; I287-Y299 PolarHBondContact N-O 3.44Å; I287-Y299 PolarHBondContact O-N 2.89Å; V289-Y299 HydrophobicContact CB-CD2 4.15Å; V289-Y299 HydrophobicContact CB-CE2 3.89Å; V289-Y299 HydrophobicContact CG2-CD2 3.5Å; V289-Y299 HydrophobicContact CG2-CE2 3.6Å; M297-Y299 HydrophobicContact CB-CD2 4.25Å; M297-Y299 HydrophobicContact CB-CE2 3.51Å; M297-Y299 WeakPolarHBondContact O-CD2 3.26Å; M297-Y299 HydrophobicContact SD-CE2 4.43Å; Y299-V310 HydrophobicContact CD1-CG1 3.5Å; Y299-V310 VanDerWaalsContact CD1-CG1 3.5Å; Y299-V310 HydrophobicContact CE1-CG1 4.4Å; Y299-V310 HydrophobicContact CG-CG1 3.82Å; Y299-I311 CarbonylContact C-O 3.39Å; Y299-I311 VanDerWaalsContact CA-O 3.22Å; Y299-I311 WeakPolarHBondContact CA-O 3.38Å; Y299-F312 VanDerWaalsContact CD1-CA 3.44Å; Y299-F312 HydrophobicContact CD1-CB 3.94Å; Y299-F312 HydrophobicContact CD1-CD2 4.33Å; Y299-F312 HydrophobicContact CE1-CB 3.68Å; Y299-F312 AromaticContact CE1-CD2 3.76Å; Y299-F312 HydrophobicContact CE1-CD2 3.76Å; Y299-F312 HydrophobicContact CE1-CG 4.22Å; Y299-F312 HydrophobicContact CE2-CD2 4.38Å; Y299-F312 AromaticContact CZ-CD2 3.77Å
300L95.5Very high93.6Very high17 Ų1742.2 Ų42.29%0.08922%0.219CC..EExtended strand (participates in β ladder)trans-101.6113.9166179.464.3000108.5L15 L302 I311 L313L15-L300 HydrophobicContact CB-CD2 4.04Å; L15-L300 HydrophobicContact CD1-CD2 4.1Å; L300-L302 HydrophobicContact CD1-CD2 4.12Å; L300-L302 HydrophobicContact CD2-CD1 4.4Å; L300-L302 HydrophobicContact CD2-CD2 3.89Å; L300-L302 HydrophobicContact CD2-CG 4.27Å; L300-L302 HydrophobicContact CG-CD2 3.79Å; L300-L302 HydrophobicContact CG-CG 4.05Å; L300-I311 HydrophobicContact CB-CB 4.41Å; L300-I311 PolarHBondContact N-O 2.94Å; L300-I311 PolarHBondContact O-N 3.25Å; L300-L313 HydrophobicContact CB-CD1 4.25Å; L300-L313 HydrophobicContact CB-CD2 4.07Å; L300-L313 HydrophobicContact CB-CG 4.32Å
301Y96.6Very high93.6Very high0 Ų041.4 Ų41.40%022%0.216CC..EExtended strand (participates in β ladder)trans-85.5135.8168.2168.3-103000109.8D260 Y263 L264 R284 W285 N303 K308 M309 V310D260-Y301 HydrophobicContact CB-CE1 3.97Å; D260-Y301 WeakPolarHBondContact CB-OH 3.43Å; D260-Y301 VanDerWaalsContact CG-OH 3.22Å; D260-Y301 PolarHBondContact OD1-OH 3.29Å; Y263-Y301 HydrophobicContact CD1-CD2 4.19Å; Y263-Y301 AromaticContact CD1-CE2 3.58Å; Y263-Y301 HydrophobicContact CD1-CE2 3.58Å; Y263-Y301 HydrophobicContact CE1-CD2 4.1Å; Y263-Y301 AromaticContact CE1-CE2 3.74Å; Y263-Y301 HydrophobicContact CE1-CE2 3.74Å; L264-Y301 HydrophobicContact CD1-CG 4.48Å; L264-Y301 HydrophobicContact CD2-CD2 3.63Å; L264-Y301 HydrophobicContact CD2-CE2 4.29Å; L264-Y301 HydrophobicContact CD2-CG 4.01Å; L264-Y301 HydrophobicContact CG-CD2 4.35Å; R284-Y301 CarbonylContact C-O 3.57Å; R284-Y301 VanDerWaalsContact CA-O 3.28Å; R284-Y301 WeakPolarHBondContact CA-O 3.28Å; W285-Y301 HydrophobicContact CB-CD1 4.01Å; W285-Y301 AromaticContact CD1-CD1 3.92Å; W285-Y301 AromaticContact CD2-CD1 3.73Å; W285-Y301 HydrophobicContact CD2-CD1 3.73Å; W285-Y301 HydrophobicContact CD2-CE1 4.13Å; W285-Y301 HydrophobicContact CE3-CD1 4.28Å; W285-Y301 AromaticContact CG-CD1 3.62Å; W285-Y301 HydrophobicContact CG-CD1 3.62Å; W285-Y301 HydrophobicContact CG-CE1 4.32Å; W285-Y301 HydrophobicContact CZ2-CE1 4.46Å; W285-Y301 PolarHBondContact N-O 3.35Å; W285-Y301 PolarHBondContact O-N 3.19Å; Y301-N303 HydrophobicContact CE1-CB 4.16Å; Y301-K308 HydrophobicContact CE2-CB 4.09Å; Y301-K308 HydrophobicContact CE2-CG 4.36Å; Y301-K308 WeakPolarHBondContact OH-CG 3.38Å; Y301-M309 WeakPolarHBondContact CA-O 3.38Å; Y301-M309 WeakPolarHBondContact CD2-O 3.3Å; Y301-V310 HydrophobicContact CD2-CG2 4.21Å
302L95.8Very high93.7Very high4 Ų445.9 Ų45.92%0.02124%0.235CC..EExtended strand (participates in β ladder)trans-130.1140.3176-55.2173.7000110.4F18 N283 R284 L300 K308 M309 I311F18-L302 HydrophobicContact CD2-CB 3.88Å; F18-L302 HydrophobicContact CD2-CD1 4.09Å; F18-L302 HydrophobicContact CE2-CB 3.22Å; F18-L302 HydrophobicContact CE2-CD1 4.28Å; F18-L302 HydrophobicContact CE2-CG 4.35Å; F18-L302 HydrophobicContact CZ-CB 3.64Å; F18-L302 WeakPolarHBondContact CZ-O 3.36Å; N283-L302 CarbonylContact O-C 3.48Å; N283-L302 WeakPolarHBondContact O-CA 3.39Å; R284-L302 HydrophobicContact CB-CD2 4.04Å; R284-L302 HydrophobicContact CG-CD2 3.61Å; L300-L302 HydrophobicContact CD1-CD2 4.12Å; L300-L302 HydrophobicContact CD2-CD1 4.4Å; L300-L302 HydrophobicContact CD2-CD2 3.89Å; L300-L302 HydrophobicContact CD2-CG 4.27Å; L300-L302 HydrophobicContact CG-CD2 3.79Å; L300-L302 HydrophobicContact CG-CG 4.05Å; L302-K308 WeakPolarHBondContact O-CA 3.3Å; L302-M309 HydrophobicContact CB-CG 3.86Å; L302-M309 HydrophobicContact CD1-CG 4.18Å; L302-M309 HydrophobicContact CD1-SD 3.92Å; L302-M309 HydrophobicContact CG-CG 4.38Å; L302-M309 PolarHBondContact N-O 3Å; L302-M309 PolarHBondContact O-N 2.89Å; L302-I311 HydrophobicContact CD1-CD1 3.77Å
303N95Very high93.8Very high27 Ų2746.5 Ų46.514%0.14424%0.239CC..EExtended strand (participates in β ladder)trans-124.4126.1168.1-173-16.5000109.1D260 N283 Y301 G306 R307D260-N303 PolarHBondContact OD1-ND2 3.01Å; N283-N303 HydrophobicContact CB-CB 4.33Å; N283-N303 WeakPolarHBondContact CB-O 3.34Å; N283-N303 PolarHBondContact O-N 2.82Å; Y301-N303 HydrophobicContact CE1-CB 4.16Å; N303-G306 WeakPolarHBondContact OD1-CA 3.25Å; N303-G306 PolarHBondContact OD1-N 2.81Å; N303-G306 VanDerWaalsContact OD1-N 3.15Å; N303-R307 CarbonylContact C-O 3.52Å; N303-R307 WeakPolarHBondContact CA-O 3.17Å
304S92.5Very high93.7Very high45 Ų4550.5 Ų50.532%0.31525%0.251SS..EExtended strand (participates in β ladder)trans-135.1109.8172-168.20000109.2F18 G306 R307F18-S304 VanDerWaalsContact CE2-CB 3.43Å; S304-G306 PolarHBondContact O-N 2.93Å; S304-R307 PolarHBondContact N-O 2.82Å; S304-R307 WeakPolarHBondContact O-CB 3.17Å; S304-R307 PolarHBondContact O-N 2.89Å
305E89.3Confident93.9Very high191 Ų19150.4 Ų50.489%0.89325%0.252SS*.THydrogen-bonded Turntrans51.141.6179.7-57.9-178.1169.800112.8R307E305-R307 VanDerWaalsContact C-N 3.3Å; E305-R307 PolarHBondContact O-N 3.39Å
306G89.6Confident93.8Very high57 Ų5752.4 Ų52.459%0.58826%0.259SS*.THydrogen-bonded Turntrans85.2-8.1179.700000114.8N303 S304 K308N303-G306 WeakPolarHBondContact OD1-CA 3.25Å; N303-G306 PolarHBondContact OD1-N 2.81Å; N303-G306 VanDerWaalsContact OD1-N 3.15Å; S304-G306 PolarHBondContact O-N 2.93Å; G306-K308 PolarHBondContact O-N 3.46Å
307R93.8Very high93.6Very high190 Ų19056.7 Ų56.772%0.71728%0.282SS*.EExtended strand (participates in β ladder)trans-78.5118.2168.3-57.2-174.6-163.4-173.95.9108.4F18 N303 S304 E305F18-R307 HydrophobicContact CE1-CB 4.22Å; F18-R307 WeakPolarHBondContact CZ-O 3.37Å; N303-R307 CarbonylContact C-O 3.52Å; N303-R307 WeakPolarHBondContact CA-O 3.17Å; S304-R307 PolarHBondContact N-O 2.82Å; S304-R307 WeakPolarHBondContact O-CB 3.17Å; S304-R307 PolarHBondContact O-N 2.89Å; E305-R307 VanDerWaalsContact C-N 3.3Å; E305-R307 PolarHBondContact O-N 3.39Å
308K95.4Very high93.5Very high61 Ų6157.8 Ų57.827%0.26530%0.296SS..EExtended strand (participates in β ladder)trans-106.5138.3-179-61.5-179.8-176.3177.80109.7D259 D260 Y263 Y301 L302 G306D259-K308 VanDerWaalsContact C-NZ 3.27Å; D259-K308 PolarHBondContact O-NZ 3.04Å; D260-K308 WeakPolarHBondContact OD1-CE 3.49Å; D260-K308 IonicContact OD1-NZ 3.4Å; Y263-K308 HydrophobicContact CD1-CB 4.09Å; Y263-K308 HydrophobicContact CD1-CD 4.05Å; Y263-K308 HydrophobicContact CD2-CB 4.04Å; Y263-K308 HydrophobicContact CD2-CD 3.69Å; Y263-K308 HydrophobicContact CE1-CB 3.86Å; Y263-K308 HydrophobicContact CE2-CB 3.78Å; Y263-K308 HydrophobicContact CE2-CD 4.32Å; Y263-K308 HydrophobicContact CG-CB 4.19Å; Y263-K308 HydrophobicContact CG-CD 3.53Å; Y263-K308 HydrophobicContact CG-CG 4.47Å; Y301-K308 HydrophobicContact CE2-CB 4.09Å; Y301-K308 HydrophobicContact CE2-CG 4.36Å; Y301-K308 WeakPolarHBondContact OH-CG 3.38Å; L302-K308 WeakPolarHBondContact O-CA 3.3Å; G306-K308 PolarHBondContact O-N 3.46Å
309M94Very high93.4Very high58 Ų5861.5 Ų61.529%0.28632%0.319SS..EExtended strand (participates in β ladder)trans-146.4157.2171.469.3172.427.400111.7F18 Y301 L302 I311F18-M309 HydrophobicContact CD1-CE 3.45Å; F18-M309 VanDerWaalsContact CD1-CE 3.45Å; F18-M309 HydrophobicContact CD1-CG 3.97Å; F18-M309 HydrophobicContact CD1-SD 3.48Å; F18-M309 WeakPolarHBondContact CD1-SD 3.36Å; F18-M309 HydrophobicContact CE1-CB 3.98Å; F18-M309 HydrophobicContact CE1-CE 3.64Å; F18-M309 HydrophobicContact CE1-CG 3.38Å; F18-M309 HydrophobicContact CE1-SD 3.58Å; F18-M309 VanDerWaalsContact CE1-SD 3.58Å; F18-M309 HydrophobicContact CE2-CG 4.39Å; F18-M309 HydrophobicContact CG-CE 4.42Å; F18-M309 HydrophobicContact CG-SD 4.02Å; F18-M309 HydrophobicContact CZ-CB 4.38Å; F18-M309 HydrophobicContact CZ-CG 3.61Å; F18-M309 HydrophobicContact CZ-SD 4.19Å; Y301-M309 WeakPolarHBondContact CA-O 3.38Å; Y301-M309 WeakPolarHBondContact CD2-O 3.3Å; L302-M309 HydrophobicContact CB-CG 3.86Å; L302-M309 HydrophobicContact CD1-CG 4.18Å; L302-M309 HydrophobicContact CD1-SD 3.92Å; L302-M309 HydrophobicContact CG-CG 4.38Å; L302-M309 PolarHBondContact N-O 3Å; L302-M309 PolarHBondContact O-N 2.89Å; M309-I311 HydrophobicContact CG-CG1 4.43Å; M309-I311 HydrophobicContact SD-CD1 3.85Å; M309-I311 HydrophobicContact SD-CG1 4.05Å
310V94.8Very high93.2Very high38 Ų3861 Ų6123%0.2332%0.319CS..EExtended strand (participates in β ladder)trans-124.4127.4173.9-174.60000108Y263 L264 T267 F268 Y299 Y301Y263-V310 HydrophobicContact CE1-CG2 3.82Å; L264-V310 HydrophobicContact CD2-CG2 3.92Å; T267-V310 HydrophobicContact CG2-CG2 4.11Å; F268-V310 HydrophobicContact CE1-CG1 4.27Å; F268-V310 HydrophobicContact CZ-CG1 3.71Å; Y299-V310 HydrophobicContact CD1-CG1 3.5Å; Y299-V310 VanDerWaalsContact CD1-CG1 3.5Å; Y299-V310 HydrophobicContact CE1-CG1 4.4Å; Y299-V310 HydrophobicContact CG-CG1 3.82Å; Y301-V310 HydrophobicContact CD2-CG2 4.21Å
311I93.4Very high93Very high14 Ų1465 Ų657%0.07234%0.34CS..EExtended strand (participates in β ladder)trans-113.1120.6-179.6-54.5-178.1000108.5P16 Y299 L300 L302 M309 L313P16-I311 HydrophobicContact CB-CD1 3.79Å; P16-I311 HydrophobicContact CB-CG2 4.2Å; P16-I311 HydrophobicContact CG-CG2 4.15Å; Y299-I311 CarbonylContact C-O 3.39Å; Y299-I311 VanDerWaalsContact CA-O 3.22Å; Y299-I311 WeakPolarHBondContact CA-O 3.38Å; L300-I311 HydrophobicContact CB-CB 4.41Å; L300-I311 PolarHBondContact N-O 2.94Å; L300-I311 PolarHBondContact O-N 3.25Å; L302-I311 HydrophobicContact CD1-CD1 3.77Å; M309-I311 HydrophobicContact CG-CG1 4.43Å; M309-I311 HydrophobicContact SD-CD1 3.85Å; M309-I311 HydrophobicContact SD-CG1 4.05Å; I311-L313 PolarHBondContact O-N 3.08Å
312F93.1Very high92.9Very high96 Ų9671.6 Ų71.642%0.42138%0.376SS..EExtended strand (participates in β ladder)trans-66130.4173173.6-104000110.9Y23 M297 Y299 Y314 A315Y23-F312 PolarHBondContact OH-O 2.83Å; M297-F312 HydrophobicContact CB-CE2 4.32Å; M297-F312 HydrophobicContact CG-CE2 4.4Å; Y299-F312 VanDerWaalsContact CD1-CA 3.44Å; Y299-F312 HydrophobicContact CD1-CB 3.94Å; Y299-F312 HydrophobicContact CD1-CD2 4.33Å; Y299-F312 HydrophobicContact CE1-CB 3.68Å; Y299-F312 AromaticContact CE1-CD2 3.76Å; Y299-F312 HydrophobicContact CE1-CD2 3.76Å; Y299-F312 HydrophobicContact CE1-CG 4.22Å; Y299-F312 HydrophobicContact CE2-CD2 4.38Å; Y299-F312 AromaticContact CZ-CD2 3.77Å; F312-Y314 VanDerWaalsContact CE2-C 3.45Å; F312-Y314 VanDerWaalsContact CZ-CA 3.43Å; F312-A315 HydrophobicContact CE2-CB 4.41Å; F312-A315 HydrophobicContact CZ-CB 4.2Å
313L92.2Very high92.6Very high16 Ų1677 Ų778%0.08440%0.4CS..EExtended strand (participates in β ladder)trans-98.6-63.1178-57.7-175.3000111.9L15 Y23 L286 L298 L300 I311L15-L313 HydrophobicContact CD1-CD1 4.29Å; L15-L313 HydrophobicContact CD2-CD1 4.49Å; L15-L313 HydrophobicContact CD2-CD2 4Å; Y23-L313 HydrophobicContact CE1-CD2 4.25Å; Y23-L313 WeakPolarHBondContact OH-CA 3.21Å; L286-L313 HydrophobicContact CD1-CD1 3.66Å; L298-L313 HydrophobicContact CB-CB 4.21Å; L298-L313 HydrophobicContact CB-CD1 4.4Å; L298-L313 WeakPolarHBondContact O-CA 3.45Å; L298-L313 WeakPolarHBondContact O-CB 3.29Å; L298-L313 PolarHBondContact O-N 3.17Å; L300-L313 HydrophobicContact CB-CD1 4.25Å; L300-L313 HydrophobicContact CB-CD2 4.07Å; L300-L313 HydrophobicContact CB-CG 4.32Å; I311-L313 PolarHBondContact O-N 3.08Å
314Y91.8Very high92.4Very high117 Ų11785.2 Ų85.246%0.45943%0.429SS..EExtended strand (participates in β ladder)trans-165.5162.417766-84000111L298 F312 I316L298-Y314 HydrophobicContact CB-CD1 4.25Å; L298-Y314 HydrophobicContact CB-CE1 3.96Å; L298-Y314 HydrophobicContact CD1-CE1 4.07Å; L298-Y314 HydrophobicContact CD1-CE2 3.84Å; L298-Y314 WeakPolarHBondContact CD1-OH 3.16Å; L298-Y314 HydrophobicContact CD2-CE1 3.89Å; L298-Y314 HydrophobicContact CG-CE1 4.18Å; L298-Y314 PolarHBondContact N-O 3.15Å; F312-Y314 VanDerWaalsContact CE2-C 3.45Å; F312-Y314 VanDerWaalsContact CZ-CA 3.43Å; Y314-I316 HydrophobicContact CE2-CG1 4.09Å
315A94.5Very high92.5Very high14 Ų1484.6 Ų84.612%0.11642%0.422CS..EExtended strand (participates in β ladder)trans-101.5133.1170.200000109.7M297 F312 N317 A318 L321M297-A315 HydrophobicContact CG-CB 4.04Å; F312-A315 HydrophobicContact CE2-CB 4.41Å; F312-A315 HydrophobicContact CZ-CB 4.2Å; A315-N317 PolarHBondContact O-N 2.79Å; A315-A318 HydrophobicContact CB-CB 4.24Å; A315-L321 HydrophobicContact CB-CD1 3.83Å; A315-L321 HydrophobicContact CB-CG 4.48Å
316I92.3Very high92.7Very high66 Ų6675.6 Ų75.634%0.33838%0.381SS..THydrogen-bonded Turntrans-66.4125.9169.9-60178000107.1M288 G296 L298 Y314M288-I316 HydrophobicContact CE-CD1 4.03Å; M288-I316 HydrophobicContact SD-CD1 4.4Å; G296-I316 WeakPolarHBondContact O-CB 3.43Å; G296-I316 WeakPolarHBondContact O-CG1 3.33Å; G296-I316 PolarHBondContact O-N 2.77Å; L298-I316 HydrophobicContact CD1-CD1 4.09Å; L298-I316 HydrophobicContact CD1-CG1 4.1Å; Y314-I316 HydrophobicContact CE2-CG1 4.09Å
317N89.9Confident92.9Very high90 Ų9079.3 Ų79.348%0.48138%0.377SS..THydrogen-bonded Turntrans49.562.4-176.1-165.8-6.3000112.7A315 V319 L320A315-N317 PolarHBondContact O-N 2.79Å; N317-V319 PolarHBondContact O-N 3.24Å; N317-L320 HydrophobicContact CB-CD1 3.92Å; N317-L320 HydrophobicContact CB-CG 4.18Å; N317-L320 WeakPolarHBondContact O-CB 3.37Å; N317-L320 PolarHBondContact O-N 3.38Å
318A92.5Very high92.8Very high55 Ų5570.9 Ų70.946%0.45535%0.345SS..G310 helixtrans-55.2-19.9-175.700000114.7A315 L320 L321A315-A318 HydrophobicContact CB-CB 4.24Å; A318-L320 PolarHBondContact O-N 2.85Å; A318-L321 WeakPolarHBondContact O-CB 3.47Å; A318-L321 WeakPolarHBondContact O-CG 3.33Å; A318-L321 PolarHBondContact O-N 3.26Å
319V92.9Very high92.6Very high91 Ų9173.6 Ų73.655%0.55235%0.353SS*.G310 helixtrans-57.7-36.5173.6179.50000110.9N317 L321 N322 H323N317-V319 PolarHBondContact O-N 3.24Å; V319-L321 PolarHBondContact O-N 3.42Å; V319-L321 VanDerWaalsContact O-N 3.14Å; V319-N322 PolarHBondContact O-N 3.23Å; V319-N322 VanDerWaalsContact O-N 3.1Å; V319-H323 PolarHBondContact O-CD2 2.93Å; V319-H323 VanDerWaalsContact O-CD2 3.25Å
320L92.7Very high92.6Very high34 Ų3472.3 Ų72.318%0.17835%0.352CS..G310 helixtrans-61.7-22.5-179.7-63.9177.7000113.7A295 N317 A318 N322 H323 Y378A295-L320 HydrophobicContact CB-CD1 3.91Å; N317-L320 HydrophobicContact CB-CD1 3.92Å; N317-L320 HydrophobicContact CB-CG 4.18Å; N317-L320 WeakPolarHBondContact O-CB 3.37Å; N317-L320 PolarHBondContact O-N 3.38Å; A318-L320 PolarHBondContact O-N 2.85Å; L320-N322 PolarHBondContact O-N 3.15Å; L320-H323 PolarHBondContact O-N 2.91Å; L320-Y378 HydrophobicContact CD1-CE2 3.93Å; L320-Y378 VanDerWaalsContact CD1-OH 3.27Å; L320-Y378 WeakPolarHBondContact CD1-OH 3.27Å
321L91.1Very high92.6Very high100 Ų10072 Ų7252%0.52435%0.35SS..G310 helixtrans-64.5-21177.2-57.8-180000112.8M297 A315 A318 V319 H323M297-L321 HydrophobicContact CE-CD1 4.35Å; M297-L321 HydrophobicContact CE-CD2 3.32Å; M297-L321 HydrophobicContact CE-CG 4.47Å; A315-L321 HydrophobicContact CB-CD1 3.83Å; A315-L321 HydrophobicContact CB-CG 4.48Å; A318-L321 WeakPolarHBondContact O-CB 3.47Å; A318-L321 WeakPolarHBondContact O-CG 3.33Å; A318-L321 PolarHBondContact O-N 3.26Å; V319-L321 PolarHBondContact O-N 3.42Å; V319-L321 VanDerWaalsContact O-N 3.14Å; L321-H323 VanDerWaalsContact C-N 3.29Å
322N93.6Very high92.8Very high140 Ų14075.7 Ų75.775%0.74937%0.367SS*.G310 helixtrans-87.20.7175.8-59.9-46.7000112.9V319 L320V319-N322 PolarHBondContact O-N 3.23Å; V319-N322 VanDerWaalsContact O-N 3.1Å; L320-N322 PolarHBondContact O-N 3.15Å
323H90.8Very high93.1Very high116 Ų11671.1 Ų71.154%0.53735%0.347SS..SBendtrans-119.3143.6-175.9-63.4-78.5000111.6V319 L320 L321 L325V319-H323 PolarHBondContact O-CD2 2.93Å; V319-H323 VanDerWaalsContact O-CD2 3.25Å; L320-H323 PolarHBondContact O-N 2.91Å; L321-H323 VanDerWaalsContact C-N 3.29Å; H323-L325 PolarHBondContact O-N 2.92Å
324R90.6Very high93.3Very high201 Ų20173.7 Ų73.776%0.75837%0.365SS*.  trans-83.2110.3170.6-177.9178.4174-177.1-4.3109.3A349R324-A349 HydrophobicContact CG-CB 4.25Å; R324-A349 PolarHBondContact NH2-O 3.45Å; R324-A349 VanDerWaalsContact NH2-O 3.12Å
325L93.9Very high93.6Very high32 Ų3268.5 Ų68.517%0.16835%0.345CS..PPolyproline II helixtrans-86.8160.1176.5-63.4-176.7000112.5V293 H323 Y378 Q383V293-L325 HydrophobicContact CB-CB 3.8Å; V293-L325 HydrophobicContact CG1-CB 3.78Å; V293-L325 WeakPolarHBondContact O-CD1 3.46Å; H323-L325 PolarHBondContact O-N 2.92Å; L325-Y378 HydrophobicContact CD1-CD2 4.06Å; L325-Y378 HydrophobicContact CD1-CE2 3.73Å; L325-Q383 HydrophobicContact CD2-CG 4.45Å
326A94.6Very high93.8Very high2 Ų274.6 Ų74.62%0.01737%0.365CS..PPolyproline II helixtrans-82.4131.1-178.100000111.5V293 T346 M347 Q383 A386V293-A326 WeakPolarHBondContact CG1-O 3.27Å; A326-T346 HydrophobicContact CB-CG2 3.65Å; A326-M347 WeakPolarHBondContact CB-O 3.44Å; A326-Q383 PolarHBondContact O-NE2 3.38Å; A326-A386 HydrophobicContact CB-CB 3.5Å
327R92.3Very high94Very high135 Ų13575.1 Ų75.151%0.50937%0.369SS..PPolyproline II helixtrans-79.5145.9178.4-71.6-73.8-167.6179.91111.3N291 D292 V293 M347N291-R327 PolarHBondContact ND2-NH1 2.9Å; D292-R327 IonicContact OD1-CZ 2.74Å; D292-R327 IonicContact OD1-NH1 3.86Å; D292-R327 PolarHBondContact OD1-NH1 3.42Å; D292-R327 WeakPolarHBondContact OD2-CA 3.16Å; D292-R327 WeakPolarHBondContact OD2-CD 3.33Å; V293-R327 HydrophobicContact CG1-CG 4.16Å; R327-M347 PolarHBondContact O-N 3.42Å
328R92.5Very high94.4Very high12 Ų1273.5 Ų73.55%0.04537%0.374CS..EExtended strand (participates in β ladder)trans-107.8133.5178.8-171.9-177.6176.6103.1-3.9110D292 Y344 L345 Y375 W376 D382 Q394D292-R328 HydrophobicContact CB-CB 3.53Å; D292-R328 PolarHBondContact OD2-N 2.93Å; R328-Y344 HydrophobicContact CG-CD1 4.42Å; R328-Y344 HydrophobicContact CG-CG 4.45Å; R328-L345 CarbonylContact C-O 3.49Å; R328-L345 VanDerWaalsContact CA-O 3.27Å; R328-L345 WeakPolarHBondContact CA-O 3.28Å; R328-Y375 PolarHBondContact NE-O 2.83Å; R328-Y375 PolarHBondContact NH2-O 2.75Å; R328-W376 PolarHBondContact O-NE1 3.48Å; R328-D382 IonicContact NH1-OD2 3.91Å; R328-D382 PolarHBondContact NH1-OD2 3.35Å; R328-Q394 VanDerWaalsContact CZ-OE1 3.28Å
329R91.5Very high94.7Very high118 Ų11873 Ų7345%0.44536%0.363SS..EExtended strand (participates in β ladder)trans-109.7127.5174.7-67.3178.6173.5178.2-4.8110.2Y344 L345R329-Y344 CarbonylContact O-C 3.59Å; R329-Y344 VanDerWaalsContact O-CA 3.28Å; R329-Y344 WeakPolarHBondContact O-CA 3.13Å; R329-L345 PolarHBondContact N-O 3.19Å; R329-L345 PolarHBondContact O-N 2.79Å
330A94.1Very high94.9Very high32 Ų3272.2 Ų72.226%0.26436%0.355SS..EExtended strand (participates in β ladder)trans-79.7132.6168.300000109.7M246 C343 Y344M246-A330 HydrophobicContact CB-CB 4.09Å; M246-A330 HydrophobicContact CG-CB 4.26Å; M246-A330 HydrophobicContact SD-CB 4.34Å; A330-C343 WeakPolarHBondContact CA-O 3.45Å; A330-Y344 HydrophobicContact CB-CD1 3.79Å; A330-Y344 HydrophobicContact CB-CE1 3.68Å
331V95.6Very high95.1Very high31 Ų3170.6 Ų70.619%0.18835%0.346CS..EExtended strand (participates in β ladder)trans-143.4138.8-179.7-63.10000110.6V333 C343 W429V331-V333 HydrophobicContact CG2-CG2 4.03Å; V331-C343 HydrophobicContact CG2-CB 3.85Å; V331-C343 PolarHBondContact N-O 2.55Å; V331-C343 PolarHBondContact O-N 3.48Å; V331-W429 HydrophobicContact CB-CH2 3.92Å; V331-W429 HydrophobicContact CB-CZ2 4.36Å; V331-W429 HydrophobicContact CG1-CH2 4Å; V331-W429 HydrophobicContact CG2-CH2 3.7Å; V331-W429 HydrophobicContact CG2-CZ2 4.43Å; V331-W429 HydrophobicContact CG2-CZ3 3.85Å
332E97.2Very high95.4Very high92 Ų9265.9 Ų65.943%0.4332%0.322SS..EExtended strand (participates in β ladder)trans-83.1129.2167.5-79.7171.2-166.100109.4Y245 M246 I340Y245-E332 VanDerWaalsContact CE1-OE1 3.29Å; Y245-E332 WeakPolarHBondContact CE1-OE1 3.48Å; Y245-E332 PolarHBondContact OH-OE1 3.37Å; M246-E332 HydrophobicContact CE-CG 3.67Å; M246-E332 WeakPolarHBondContact CE-OE1 3.34Å; E332-I340 HydrophobicContact CB-CG2 3.64Å; E332-I340 HydrophobicContact CG-CG2 3.69Å
333V97.9Very high95.6Very high0 Ų059.2 Ų59.20%029%0.286CS..EExtended strand (participates in β ladder)trans-120.4120.3179.2-178.50000109.8V331 Q341 C343 W429V331-V333 HydrophobicContact CG2-CG2 4.03Å; V333-Q341 HydrophobicContact CB-CG 4.07Å; V333-Q341 PolarHBondContact N-O 3.39Å; V333-Q341 VanDerWaalsContact O-CG 3.24Å; V333-Q341 WeakPolarHBondContact O-CG 3.41Å; V333-Q341 PolarHBondContact O-N 2.86Å; V333-C343 HydrophobicContact CG2-CB 3.96Å; V333-C343 VanDerWaalsContact CG2-SG 3.6Å; V333-W429 HydrophobicContact CB-CD2 4.45Å; V333-W429 HydrophobicContact CB-CG 4.34Å; V333-W429 HydrophobicContact CG1-CB 3.5Å; V333-W429 VanDerWaalsContact CG1-CB 3.5Å; V333-W429 HydrophobicContact CG1-CD2 4.06Å; V333-W429 HydrophobicContact CG1-CG 3.5Å; V333-W429 HydrophobicContact CG2-CD2 3.66Å; V333-W429 HydrophobicContact CG2-CE3 3.75Å; V333-W429 HydrophobicContact CG2-CG 4.06Å; V333-W429 HydrophobicContact CG2-CZ2 4.47Å; V333-W429 HydrophobicContact CG2-CZ3 4.24Å
334P97.8Very high95.9Very high69 Ų6953.7 Ų53.745%0.44826%0.261SS..EExtended strand (participates in β ladder)trans-72.8134.1172.829.5-32.8000110.7L339 I340P334-L339 CarbonylContact C-O 3.55Å; P334-L339 WeakPolarHBondContact CA-O 3.38Å; P334-I340 HydrophobicContact CB-CD1 3.85Å
335T98.3Very high96.1Very high8 Ų844.2 Ų44.25%0.04923%0.225CC..  trans-81.2165.8166.766.60000109.7D337 G338 L339 Q341 D422T335-D337 PolarHBondContact O-N 2.98Å; T335-D337 VanDerWaalsContact O-N 3.16Å; T335-D337 PolarHBondContact OG1-OD1 3.24Å; T335-G338 PolarHBondContact O-N 3.25Å; T335-L339 HydrophobicContact CG2-CB 4.17Å; T335-L339 WeakPolarHBondContact CG2-O 3.29Å; T335-L339 PolarHBondContact N-O 3.36Å; T335-L339 WeakPolarHBondContact OG1-CA 3.29Å; T335-L339 VanDerWaalsContact OG1-CB 3.28Å; T335-L339 WeakPolarHBondContact OG1-CB 3.26Å; T335-L339 PolarHBondContact OG1-N 3.28Å; T335-L339 PolarHBondContact OG1-O 3.32Å; T335-L339 VanDerWaalsContact OG1-O 3.07Å; T335-Q341 HydrophobicContact CG2-CG 4.15Å; T335-D422 HydrophobicContact CG2-CB 4.1Å; T335-D422 WeakPolarHBondContact CG2-OD1 3.2Å
336R97.6Very high96.2Very high142 Ų14242.8 Ų42.854%0.53622%0.218SC..THydrogen-bonded Turntrans-62.4-21.1-179.569.5-176.566.6158.710.7115D421 D425R336-D421 IonicContact CZ-OD1 3.66Å; R336-D421 IonicContact CZ-OD2 3.3Å; R336-D421 IonicContact NH1-OD1 3.72Å; R336-D421 PolarHBondContact NH1-OD1 2.77Å; R336-D421 IonicContact NH1-OD2 2.7Å; R336-D421 PolarHBondContact NH1-OD2 3.13Å; R336-D421 IonicContact NH2-OD1 3.33Å; R336-D421 PolarHBondContact NH2-OD1 2.98Å; R336-D425 WeakPolarHBondContact CB-OD2 3.46Å; R336-D425 WeakPolarHBondContact CG-OD2 3.28Å; R336-D425 IonicContact CZ-OD1 3.67Å; R336-D425 VanDerWaalsContact CZ-OD1 3.28Å; R336-D425 PolarHBondContact N-OD2 3.07Å; R336-D425 IonicContact NE-OD1 3.82Å; R336-D425 PolarHBondContact NE-OD1 2.81Å; R336-D425 IonicContact NE-OD2 3.54Å; R336-D425 PolarHBondContact NE-OD2 2.85Å; R336-D425 IonicContact NH2-OD1 3.43Å; R336-D425 PolarHBondContact NH2-OD1 2.66Å; R336-D425 IonicContact NH2-OD2 2.78Å
337D97.6Very high96.1Very high78 Ų7843.3 Ų43.342%0.41722%0.22SC..THydrogen-bonded Turntrans-998.7175.167.9-18.4000113.1T335 R398 R418T335-D337 PolarHBondContact O-N 2.98Å; T335-D337 VanDerWaalsContact O-N 3.16Å; T335-D337 PolarHBondContact OG1-OD1 3.24Å; D337-R398 IonicContact OD1-CZ 3.18Å; D337-R398 IonicContact OD1-NH1 3.88Å; D337-R398 IonicContact OD1-NH2 2.99Å; D337-R398 PolarHBondContact OD1-NH2 3.06Å; D337-R398 IonicContact OD2-CZ 3.98Å; D337-R398 IonicContact OD2-NH1 3.53Å; D337-R398 PolarHBondContact OD2-NH1 3.09Å; D337-R398 IonicContact OD2-NH2 2.74Å; D337-R398 PolarHBondContact OD2-NH2 2.62Å; D337-R418 IonicContact OD2-NH1 2.66Å
338G97.4Very high96.1Very high56 Ų5637.4 Ų37.458%0.57720%0.199SC*.SBendtrans86.63.3173.100000115.3T335T335-G338 PolarHBondContact O-N 3.25Å
339L98Very high95.7Very high45 Ų4538 Ų3824%0.23621%0.206CC..PPolyproline II helixtrans-66.2139.9168.8-172.576.3000109.3P334 T335 R398 F407P334-L339 CarbonylContact C-O 3.55Å; P334-L339 WeakPolarHBondContact CA-O 3.38Å; T335-L339 HydrophobicContact CG2-CB 4.17Å; T335-L339 WeakPolarHBondContact CG2-O 3.29Å; T335-L339 PolarHBondContact N-O 3.36Å; T335-L339 WeakPolarHBondContact OG1-CA 3.29Å; T335-L339 VanDerWaalsContact OG1-CB 3.28Å; T335-L339 WeakPolarHBondContact OG1-CB 3.26Å; T335-L339 PolarHBondContact OG1-N 3.28Å; T335-L339 PolarHBondContact OG1-O 3.32Å; T335-L339 VanDerWaalsContact OG1-O 3.07Å; L339-R398 HydrophobicContact CD2-CB 3.57Å; L339-F407 HydrophobicContact CD1-CD2 3.92Å; L339-F407 HydrophobicContact CD1-CE2 3.99Å; L339-F407 HydrophobicContact CD2-CD2 4.28Å; L339-F407 HydrophobicContact CD2-CE2 3.72Å; L339-F407 HydrophobicContact CD2-CZ 4.24Å; L339-F407 HydrophobicContact CG-CD2 4.34Å; L339-F407 HydrophobicContact CG-CE2 3.89Å
340I97.9Very high95.1Very high73 Ų7342.1 Ų42.137%0.37423%0.227SC..EExtended strand (participates in β ladder)trans-98118.1173.3-54.9-55.2000108.7E332 P334 F407E332-I340 HydrophobicContact CB-CG2 3.64Å; E332-I340 HydrophobicContact CG-CG2 3.69Å; P334-I340 HydrophobicContact CB-CD1 3.85Å; I340-F407 WeakPolarHBondContact O-CE2 3.1Å
341Q97.4Very high94.3Very high0 Ų042.7 Ų42.70%022%0.223CC..EExtended strand (participates in β ladder)trans-101.8139.2171.454.6178.9-28.700110.4V333 T335 N396 D422V333-Q341 HydrophobicContact CB-CG 4.07Å; V333-Q341 PolarHBondContact N-O 3.39Å; V333-Q341 VanDerWaalsContact O-CG 3.24Å; V333-Q341 WeakPolarHBondContact O-CG 3.41Å; V333-Q341 PolarHBondContact O-N 2.86Å; T335-Q341 HydrophobicContact CG2-CG 4.15Å; Q341-N396 VanDerWaalsContact CB-O 3.26Å; Q341-N396 WeakPolarHBondContact CB-O 3.46Å; Q341-D422 PolarHBondContact NE2-O 2.73Å
342L97.5Very high93Very high2 Ų248.8 Ų48.81%0.0125%0.247CC..EExtended strand (participates in β ladder)trans-87.3121175.7179.766.1000109.8Y245 M246 Y344 N396 F403Y245-L342 WeakPolarHBondContact O-CD2 3.19Å; M246-L342 HydrophobicContact CE-CD1 4.24Å; M246-L342 HydrophobicContact CG-CD1 3.76Å; M246-L342 HydrophobicContact CG-CD2 4.46Å; L342-Y344 HydrophobicContact CD2-CE2 4.43Å; L342-Y344 WeakPolarHBondContact CD2-OH 3.44Å; L342-Y344 HydrophobicContact CG-CE2 4.5Å; L342-N396 WeakPolarHBondContact O-CB 3.21Å; L342-N396 PolarHBondContact O-N 2.91Å; L342-N396 PolarHBondContact O-ND2 3.34Å; L342-F403 HydrophobicContact CB-CE1 3.96Å; L342-F403 HydrophobicContact CB-CZ 3.98Å; L342-F403 HydrophobicContact CD2-CE1 3.94Å; L342-F403 HydrophobicContact CD2-CZ 4.03Å
343C97.7Very high91.6Very high0 Ų046.6 Ų46.60%024%0.24CC..EExtended strand (participates in β ladder)trans-116158.2179.5-64.90000111.8A330 V331 V333 L393 Q394 C395A330-C343 WeakPolarHBondContact CA-O 3.45Å; V331-C343 HydrophobicContact CG2-CB 3.85Å; V331-C343 PolarHBondContact N-O 2.55Å; V331-C343 PolarHBondContact O-N 3.48Å; V333-C343 HydrophobicContact CG2-CB 3.96Å; V333-C343 VanDerWaalsContact CG2-SG 3.6Å; C343-L393 HydrophobicContact CB-CD1 4Å; C343-Q394 CarbonylContact C-O 3.51Å; C343-Q394 VanDerWaalsContact CA-O 3.29Å; C343-Q394 WeakPolarHBondContact CA-O 3.46Å; C343-C395 HydrophobicContact CB-CB 4.1Å; C343-C395 WeakPolarHBondContact CB-SG 3.31Å; C343-C395 WeakPolarHBondContact SG-CB 3.45Å; C343-C395 CovalentContact SG-SG 2.03Å; C343-C395 PolarHBondContact SG-SG 3.23Å
344Y96.5Very high90.1Very high0 Ų053.7 Ų53.70%028%0.278CS..EExtended strand (participates in β ladder)trans-130133.3173.3-58-75.8000110.9R328 R329 A330 L342 V374 W376 Q394R328-Y344 HydrophobicContact CG-CD1 4.42Å; R328-Y344 HydrophobicContact CG-CG 4.45Å; R329-Y344 CarbonylContact O-C 3.59Å; R329-Y344 VanDerWaalsContact O-CA 3.28Å; R329-Y344 WeakPolarHBondContact O-CA 3.13Å; A330-Y344 HydrophobicContact CB-CD1 3.79Å; A330-Y344 HydrophobicContact CB-CE1 3.68Å; L342-Y344 HydrophobicContact CD2-CE2 4.43Å; L342-Y344 WeakPolarHBondContact CD2-OH 3.44Å; L342-Y344 HydrophobicContact CG-CE2 4.5Å; Y344-V374 HydrophobicContact CD2-CB 4.35Å; Y344-V374 HydrophobicContact CD2-CG2 3.69Å; Y344-V374 HydrophobicContact CE2-CB 4.46Å; Y344-V374 HydrophobicContact CE2-CG2 3.9Å; Y344-V374 WeakPolarHBondContact CE2-O 3.21Å; Y344-W376 HydrophobicContact CD1-CB 4.07Å; Y344-W376 AromaticContact CD1-CD1 3.88Å; Y344-W376 HydrophobicContact CD1-CG 4.39Å; Y344-W376 HydrophobicContact CE1-CB 3.51Å; Y344-W376 HydrophobicContact CE1-CG 4.21Å; Y344-W376 PolarHBondContact OH-N 3.17Å; Y344-Q394 PolarHBondContact N-O 3.34Å; Y344-Q394 PolarHBondContact O-N 3.25Å
345L95.9Very high88.9Confident2 Ų253.9 Ų53.91%0.0128%0.275CS..EExtended strand (participates in β ladder)trans-119.9108.9-173.5-160.883.9000110R328 R329 M347 V391 V392 L393 L435R328-L345 CarbonylContact C-O 3.49Å; R328-L345 VanDerWaalsContact CA-O 3.27Å; R328-L345 WeakPolarHBondContact CA-O 3.28Å; R329-L345 PolarHBondContact N-O 3.19Å; R329-L345 PolarHBondContact O-N 2.79Å; L345-M347 HydrophobicContact CD2-CG 4.31Å; L345-M347 HydrophobicContact CD2-SD 3.31Å; L345-M347 WeakPolarHBondContact CD2-SD 3.39Å; L345-M347 HydrophobicContact CG-SD 3.78Å; L345-V391 HydrophobicContact CD1-CG1 3.51Å; L345-V391 HydrophobicContact CD2-CG1 4.24Å; L345-V391 HydrophobicContact CG-CG1 3.71Å; L345-V392 CarbonylContact C-O 3.6Å; L345-V392 WeakPolarHBondContact CA-O 3.47Å; L345-L393 HydrophobicContact CD1-CB 4.12Å; L345-L393 HydrophobicContact CD1-CD1 3.65Å; L345-L393 HydrophobicContact CD1-CG 4.44Å; L345-L435 HydrophobicContact CD2-CB 4.24Å; L345-L435 HydrophobicContact CD2-CD1 3.79Å; L345-L435 HydrophobicContact CD2-CD2 4.37Å; L345-L435 HydrophobicContact CD2-CG 4.35Å
346T96.1Very high87.4Confident2 Ų257 Ų571%0.01229%0.291CS..EExtended strand (participates in β ladder)trans-91.7115175.5-53.10000108.7A326 D382 A386 V391 V392A326-T346 HydrophobicContact CB-CG2 3.65Å; T346-D382 HydrophobicContact CG2-CB 4.33Å; T346-D382 PolarHBondContact OG1-OD2 3.25Å; T346-A386 HydrophobicContact CG2-CB 3.84Å; T346-V391 WeakPolarHBondContact O-CA 3.39Å; T346-V392 PolarHBondContact N-O 3.17Å; T346-V392 PolarHBondContact O-N 2.84Å
347M92.4Very high86.3Confident13 Ų1354.7 Ų54.76%0.06430%0.297CS..  trans-97.3136.7-174.7-61.1-61.7-65.500110.8A326 R327 L345 A349 Y351 V353 V391A326-M347 WeakPolarHBondContact CB-O 3.44Å; R327-M347 PolarHBondContact O-N 3.42Å; L345-M347 HydrophobicContact CD2-CG 4.31Å; L345-M347 HydrophobicContact CD2-SD 3.31Å; L345-M347 WeakPolarHBondContact CD2-SD 3.39Å; L345-M347 HydrophobicContact CG-SD 3.78Å; M347-A349 PolarHBondContact O-N 3.44Å; M347-Y351 HydrophobicContact CE-CD1 3.49Å; M347-Y351 VanDerWaalsContact CE-CD1 3.49Å; M347-Y351 HydrophobicContact CE-CE1 3.65Å; M347-V353 HydrophobicContact CE-CG2 4.48Å; M347-V391 HydrophobicContact CE-CG2 3.56Å; M347-V391 HydrophobicContact SD-CB 4.37Å; M347-V391 HydrophobicContact SD-CG1 3.84Å; M347-V391 HydrophobicContact SD-CG2 3.61Å
348P91.3Very high85.5Confident10 Ų1058.5 Ų58.57%0.06531%0.312CS..  trans-50.5130.2175.2-25.431.5000111.5K350 Y351 A386 G389 Y390 V391P348-K350 PolarHBondContact O-N 3.25Å; P348-Y351 WeakPolarHBondContact O-CB 3.37Å; P348-Y351 PolarHBondContact O-N 2.88Å; P348-A386 WeakPolarHBondContact CB-O 3.43Å; P348-G389 VanDerWaalsContact CG-C 3.49Å; P348-G389 WeakPolarHBondContact CG-O 3.22Å; P348-Y390 WeakPolarHBondContact CD-O 3.4Å; P348-Y390 VanDerWaalsContact CG-O 3.29Å; P348-Y390 WeakPolarHBondContact CG-O 3.35Å; P348-V391 HydrophobicContact CG-CG2 4.41Å
349A84.1Confident85.2Confident25 Ų2557.3 Ų57.321%0.20729%0.293CS..THydrogen-bonded Turntrans-59.6-23.1-173.900000113.9R324 M347R324-A349 HydrophobicContact CG-CB 4.25Å; R324-A349 PolarHBondContact NH2-O 3.45Å; R324-A349 VanDerWaalsContact NH2-O 3.12Å; M347-A349 PolarHBondContact O-N 3.44Å
350K79.4Confident84.9Confident204 Ų20455.7 Ų55.789%0.88729%0.285SS*.THydrogen-bonded Turntrans-88-13.9177.3-64.8-179.8-179.11730113.6P348P348-K350 PolarHBondContact O-N 3.25Å
351Y76.1Confident84.8Confident45 Ų4552.4 Ų52.418%0.17627%0.268CS..  trans-78.1129-176.9-175.7-107.8000111.2M347 P348 V353 D355 Q358 L359 P360M347-Y351 HydrophobicContact CE-CD1 3.49Å; M347-Y351 VanDerWaalsContact CE-CD1 3.49Å; M347-Y351 HydrophobicContact CE-CE1 3.65Å; P348-Y351 WeakPolarHBondContact O-CB 3.37Å; P348-Y351 PolarHBondContact O-N 2.88Å; Y351-V353 HydrophobicContact CD1-CG2 4.43Å; Y351-D355 PolarHBondContact OH-O 3.06Å; Y351-Q358 WeakPolarHBondContact CE2-O 3.3Å; Y351-L359 WeakPolarHBondContact OH-CD2 3.45Å; Y351-P360 HydrophobicContact CD2-CG 4.35Å; Y351-P360 HydrophobicContact CE1-CG 4.39Å; Y351-P360 HydrophobicContact CE2-CG 4.21Å
352K68.9Low84.7Confident159 Ų15952.6 Ų52.669%0.69127%0.27SS*.  trans-88.7111.2171.5-71.4-175.7-178.9177.70108.5N354 D355K352-N354 PolarHBondContact O-N 2.82Å; K352-D355 HydrophobicContact CB-CB 4.15Å; K352-D355 WeakPolarHBondContact O-CB 3.22Å; K352-D355 PolarHBondContact O-N 2.83Å; K352-D355 VanDerWaalsContact O-N 3.08Å
353V67.3Low84.7Confident45 Ų4552.5 Ų52.527%0.27327%0.27SS..THydrogen-bonded Turntrans-57.1133.2172.1179.20000108.9M347 Y351M347-V353 HydrophobicContact CE-CG2 4.48Å; Y351-V353 HydrophobicContact CD1-CG2 4.43Å
354N67.4Low84.8Confident150 Ų15052.7 Ų52.780%0.80227%0.271SS*.THydrogen-bonded Turntrans77.710.9-173.9-46.8-33.5000116K352 D356K352-N354 PolarHBondContact O-N 2.82Å; N354-D356 PolarHBondContact O-N 3.3Å
355D72.4Confident84.9Confident73 Ų7353 Ų5339%0.3927%0.272SS..  trans-89.891.9163.7-168.2-16.4000110Y351 K352 S357Y351-D355 PolarHBondContact OH-O 3.06Å; K352-D355 HydrophobicContact CB-CB 4.15Å; K352-D355 WeakPolarHBondContact O-CB 3.22Å; K352-D355 PolarHBondContact O-N 2.83Å; K352-D355 VanDerWaalsContact O-N 3.08Å; D355-S357 PolarHBondContact O-N 2.85Å; D355-S357 VanDerWaalsContact OD1-CB 3.27Å; D355-S357 WeakPolarHBondContact OD1-CB 3.17Å; D355-S357 PolarHBondContact OD1-N 2.82Å; D355-S357 VanDerWaalsContact OD1-N 3.16Å; D355-S357 PolarHBondContact OD1-OG 2.86Å
356D67.6Low85Confident73 Ų7353.1 Ų53.139%0.3927%0.273SS..THydrogen-bonded Turntrans-71.1-4.4-177.9-83.4-18.8000114.3N354 Q358 R434N354-D356 PolarHBondContact O-N 3.3Å; D356-Q358 VanDerWaalsContact C-N 3.28Å; D356-Q358 PolarHBondContact O-N 2.91Å; D356-R434 VanDerWaalsContact CB-NH2 3.28Å; D356-R434 IonicContact OD1-CZ 2.94Å; D356-R434 IonicContact OD1-NE 3.64Å; D356-R434 PolarHBondContact OD1-NE 2.65Å; D356-R434 IonicContact OD1-NH1 2.69Å; D356-R434 IonicContact OD1-NH2 3.2Å; D356-R434 PolarHBondContact OD1-NH2 2.83Å; D356-R434 IonicContact OD2-CZ 2.79Å; D356-R434 IonicContact OD2-NE 3.86Å; D356-R434 IonicContact OD2-NH1 3.48Å; D356-R434 PolarHBondContact OD2-NH1 2.69Å; D356-R434 IonicContact OD2-NH2 3.34Å; D356-R434 PolarHBondContact OD2-NH2 2.82Å
357S73.1Confident85.1Confident94 Ų9454 Ų5466%0.65728%0.277SS*.THydrogen-bonded Turntrans-67.2-29.8-174.665.20000112.8D355D355-S357 PolarHBondContact O-N 2.85Å; D355-S357 VanDerWaalsContact OD1-CB 3.27Å; D355-S357 WeakPolarHBondContact OD1-CB 3.17Å; D355-S357 PolarHBondContact OD1-N 2.82Å; D355-S357 VanDerWaalsContact OD1-N 3.16Å; D355-S357 PolarHBondContact OD1-OG 2.86Å
358Q81.3Confident85.3Confident157 Ų15754.3 Ų54.373%0.73428%0.284SS*.SBendtrans-15198.6172.6-69.9-167.6-5.200111.8Y351 D356Y351-Q358 WeakPolarHBondContact CE2-O 3.3Å; D356-Q358 VanDerWaalsContact C-N 3.28Å; D356-Q358 PolarHBondContact O-N 2.91Å
359L90.1Very high85.4Confident32 Ų3255.1 Ų55.117%0.16829%0.293CS..PPolyproline II helixtrans-65.8137.5172.1-61.5-176.2000110.6Y351 R434 V436 D437 R440Y351-L359 WeakPolarHBondContact OH-CD2 3.45Å; L359-R434 HydrophobicContact CD1-CB 4.13Å; L359-R434 HydrophobicContact CD2-CB 4.25Å; L359-R434 WeakPolarHBondContact CD2-O 3.49Å; L359-V436 WeakPolarHBondContact CD1-O 3.38Å; L359-D437 HydrophobicContact CB-CB 4.04Å; L359-R440 PolarHBondContact O-NH2 2.82Å
360P92.6Very high85.9Confident11 Ų1154 Ų547%0.07128%0.284CS..PPolyproline II helixtrans-72.1157.218030.8-35.3000111.1Y351 V391 L435 V436 D437Y351-P360 HydrophobicContact CD2-CG 4.35Å; Y351-P360 HydrophobicContact CE1-CG 4.39Å; Y351-P360 HydrophobicContact CE2-CG 4.21Å; P360-V391 HydrophobicContact CB-CG2 3.97Å; P360-V391 HydrophobicContact CG-CB 4.36Å; P360-V391 HydrophobicContact CG-CG2 3.27Å; P360-L435 WeakPolarHBondContact CG-O 3.5Å; P360-V436 CarbonylContact O-C 3.48Å; P360-V436 WeakPolarHBondContact O-CA 3.39Å; P360-D437 PolarHBondContact O-N 3.47Å
361A95Very high86.7Confident3 Ų345.5 Ų45.53%0.02525%0.248CC..PPolyproline II helixtrans-69.8149.5168.600000110.6Y390 V391 R440 L590A361-Y390 HydrophobicContact CB-CD1 3.88Å; A361-Y390 HydrophobicContact CB-CE1 4.2Å; A361-Y390 CarbonylContact O-C 3.6Å; A361-Y390 WeakPolarHBondContact O-CA 3.48Å; A361-V391 PolarHBondContact O-N 3.22Å; A361-R440 CarbonylContact C-O 3.55Å; A361-R440 WeakPolarHBondContact CA-O 3.44Å; A361-R440 HydrophobicContact CB-CB 3.71Å; A361-R440 VanDerWaalsContact CB-O 3.25Å; A361-R440 WeakPolarHBondContact CB-O 3.39Å; A361-L590 HydrophobicContact CB-CB 3.9Å; A361-L590 HydrophobicContact CB-CD1 4.31Å; A361-L590 HydrophobicContact CB-CG 4.48Å
362G96.3Very high87.7Confident4 Ų450.7 Ų50.74%0.04127%0.268CS..EExtended strand (participates in β ladder)trans-109.9143.3-177.100000113.6V391 R440 M441 A442G362-V391 CarbonylContact C-O 3.56Å; G362-V391 VanDerWaalsContact CA-O 3.31Å; G362-V391 WeakPolarHBondContact CA-O 3.48Å; G362-R440 PolarHBondContact N-O 2.66Å; G362-M441 CarbonylContact O-C 3.3Å; G362-M441 WeakPolarHBondContact O-CA 3.17Å; G362-M441 WeakPolarHBondContact O-CB 3.5Å; G362-A442 PolarHBondContact O-N 3.4Å
363I98.3Very high89Confident1 Ų144.2 Ų44.21%0.00524%0.239CC..EExtended strand (participates in β ladder)trans-118.3117.6168.4-47.3-63.5000108.1V365 L385 Y390 V391 L393 A442 M444 F586 L590I363-V365 HydrophobicContact CG2-CG2 3.87Å; I363-V365 PolarHBondContact O-N 2.97Å; I363-L385 HydrophobicContact CB-CD1 4.49Å; I363-L385 HydrophobicContact CG2-CD1 4.2Å; I363-Y390 HydrophobicContact CD1-CD1 4.21Å; I363-Y390 HydrophobicContact CD1-CD2 4.43Å; I363-Y390 HydrophobicContact CD1-CG 4.1Å; I363-Y390 HydrophobicContact CG1-CD1 4.4Å; I363-Y390 HydrophobicContact CG1-CD2 4.22Å; I363-Y390 HydrophobicContact CG1-CG 3.87Å; I363-V391 PolarHBondContact N-O 3.31Å; I363-L393 PolarHBondContact O-N 3.46Å; I363-A442 HydrophobicContact CD1-CB 3.77Å; I363-M444 HydrophobicContact CG2-CG 3.7Å; I363-M444 HydrophobicContact CG2-SD 3.73Å; I363-F586 HydrophobicContact CD1-CD1 4.33Å; I363-F586 HydrophobicContact CD1-CD2 3.76Å; I363-F586 HydrophobicContact CD1-CE1 4.34Å; I363-F586 HydrophobicContact CD1-CE2 3.75Å; I363-F586 HydrophobicContact CD1-CG 4.06Å; I363-F586 HydrophobicContact CD1-CZ 4.05Å; I363-F586 HydrophobicContact CG1-CD2 4.43Å; I363-F586 HydrophobicContact CG1-CE2 4.23Å; I363-F586 HydrophobicContact CG2-CE2 4.02Å; I363-F586 HydrophobicContact CG2-CZ 4.08Å; I363-L590 HydrophobicContact CD1-CD1 3.36Å
364N98Very high90.4Very high3 Ų342.8 Ų42.82%0.01623%0.23CC..EExtended strand (participates in β ladder)trans-87.4104.4172.6-161.41.3000108.7I366 L393 I423 A442 I443 M444 Y464N364-I366 HydrophobicContact CB-CD1 4.35Å; N364-I366 VanDerWaalsContact OD1-CD1 3.3Å; N364-I366 WeakPolarHBondContact OD1-CD1 3.49Å; N364-L393 PolarHBondContact OD1-O 2.9Å; N364-I423 WeakPolarHBondContact ND2-CG2 3.46Å; N364-I423 PolarHBondContact ND2-O 3.44Å; N364-I423 VanDerWaalsContact ND2-O 3.1Å; N364-A442 PolarHBondContact N-O 2.99Å; N364-I443 WeakPolarHBondContact O-CA 3.43Å; N364-M444 PolarHBondContact O-N 3.4Å; N364-Y464 HydrophobicContact CB-CE1 4.17Å; N364-Y464 PolarHBondContact ND2-OH 2.78Å
365V98.4Very high91.6Very high6 Ų638.1 Ų38.14%0.03620%0.202CC..EExtended strand (participates in β ladder)trans-96.6113.4-177.1176.30000108.8I363 E381 L385 V392 L393 Q394 M444I363-V365 HydrophobicContact CG2-CG2 3.87Å; I363-V365 PolarHBondContact O-N 2.97Å; V365-E381 WeakPolarHBondContact CG1-OE1 3.29Å; V365-L385 HydrophobicContact CG2-CD1 4.08Å; V365-V392 HydrophobicContact CB-CG1 4.21Å; V365-V392 HydrophobicContact CG2-CG1 3.52Å; V365-L393 PolarHBondContact N-O 3.4Å; V365-Q394 HydrophobicContact CB-CG 3.76Å; V365-Q394 HydrophobicContact CG1-CG 4.03Å; V365-M444 WeakPolarHBondContact CA-O 3.23Å; V365-M444 HydrophobicContact CB-CG 4.33Å; V365-M444 HydrophobicContact CG2-CG 3.69Å; V365-M444 HydrophobicContact CG2-SD 3.98Å
366I98.5Very high92.5Very high5 Ų536.2 Ų36.23%0.02619%0.189CC..EExtended strand (participates in β ladder)trans-101121.1-172.6-45.1-51.8000109.2N364 F397 I423 I443 M444 Y448 G449 A452N364-I366 HydrophobicContact CB-CD1 4.35Å; N364-I366 VanDerWaalsContact OD1-CD1 3.3Å; N364-I366 WeakPolarHBondContact OD1-CD1 3.49Å; I366-F397 HydrophobicContact CG2-CD1 4.43Å; I366-F397 HydrophobicContact CG2-CE1 3.62Å; I366-F397 HydrophobicContact CG2-CZ 4.2Å; I366-I423 HydrophobicContact CD1-CB 4.41Å; I366-I423 HydrophobicContact CD1-CD1 4.23Å; I366-I423 HydrophobicContact CD1-CG1 4.11Å; I366-I423 HydrophobicContact CD1-CG2 3.5Å; I366-I423 VanDerWaalsContact CD1-CG2 3.5Å; I366-I423 HydrophobicContact CG1-CD1 4.39Å; I366-I423 HydrophobicContact CG1-CG2 4.28Å; I366-I423 HydrophobicContact CG2-CD1 3.71Å; I366-I423 HydrophobicContact CG2-CG1 4.45Å; I366-I443 HydrophobicContact CD1-CD1 4.43Å; I366-I443 HydrophobicContact CD1-CG1 4.46Å; I366-I443 HydrophobicContact CG1-CD1 4Å; I366-I443 HydrophobicContact CG1-CG1 3.93Å; I366-M444 PolarHBondContact N-O 3.03Å; I366-Y448 HydrophobicContact CG2-CE1 4.39Å; I366-G449 WeakPolarHBondContact O-CA 3.4Å; I366-A452 HydrophobicContact CG2-CB 4.01Å
367H98Very high93.7Very high22 Ų2236.9 Ų36.910%0.10219%0.19CC..  trans-69.5147.8178.168.577.7000112P370 R372 V374 C395 F397 S400H367-P370 PolarHBondContact CE1-O 3.44Å; H367-R372 PolarHBondContact CE1-O 2.69Å; H367-V374 HydrophobicContact CB-CG1 3.97Å; H367-C395 PolarHBondContact CD2-O 3.16Å; H367-F397 AromaticContact CD2-CE1 3.7Å; H367-F397 AromaticContact CE1-CE1 3.71Å; H367-F397 AromaticContact CE1-CE2 3.96Å; H367-F397 AromaticContact CE1-CZ 3.3Å; H367-F397 WeakPolarHBondContact CE1-CZ 3.27Å; H367-F397 AromaticContact ND1-CZ 3.82Å; H367-F397 AromaticContact NE2-CE1 3.38Å; H367-F397 WeakPolarHBondContact NE2-CE1 3.44Å; H367-F397 AromaticContact NE2-CZ 3.49Å; H367-F397 WeakPolarHBondContact NE2-CZ 3.46Å; H367-S400 PolarHBondContact NE2-OG 3.27Å; H367-S400 VanDerWaalsContact NE2-OG 3.17Å
368G97Very high94.6Very high19 Ų1934.9 Ų34.920%0.19617%0.168CC..SBendtrans-69.6179.2171.500000113.2A446G368-A446 WeakPolarHBondContact CA-O 3.5Å
369G93Very high95.3Very high26 Ų2628.8 Ų28.827%0.26814%0.143SC..SBendtrans129.8-97.3179.300000112.3
370P95.8Very high95.5Very high2 Ų230.9 Ų30.91%0.01316%0.16CC..SBendcis-80.3-10.77.629.6-37.3000115H367 R372 F397 W415 M419 Y448H367-P370 PolarHBondContact CE1-O 3.44Å; P370-R372 PolarHBondContact O-N 2.78Å; P370-F397 HydrophobicContact CB-CE2 3.92Å; P370-F397 HydrophobicContact CB-CZ 4.45Å; P370-W415 VanDerWaalsContact CD-CZ2 3.41Å; P370-W415 HydrophobicContact CG-CZ2 4.13Å; P370-M419 HydrophobicContact CB-CE 3.38Å; P370-M419 HydrophobicContact CG-CE 3.76Å; P370-Y448 HydrophobicContact CB-CD1 3.73Å; P370-Y448 HydrophobicContact CB-CD2 3.86Å; P370-Y448 HydrophobicContact CB-CE1 4Å; P370-Y448 HydrophobicContact CB-CE2 4.08Å; P370-Y448 HydrophobicContact CB-CG 3.67Å; P370-Y448 HydrophobicContact CG-CD2 4.05Å; P370-Y448 HydrophobicContact CG-CE2 4.3Å; P370-Y448 HydrophobicContact CG-CG 4.27Å
371N95.9Very high95.6Very high25 Ų2532.4 Ų32.413%0.13417%0.167CC..SBendtrans-78.863.9-177.9-49.7104.3000111.1M178 G399 T401 L408 R497M178-N371 HydrophobicContact CE-CB 3.99Å; N371-G399 WeakPolarHBondContact CA-O 3.49Å; N371-G399 PolarHBondContact ND2-O 3.42Å; N371-T401 HydrophobicContact CB-CG2 4.32Å; N371-T401 WeakPolarHBondContact O-CG2 3.32Å; N371-L408 HydrophobicContact CB-CD1 3.96Å; N371-L408 WeakPolarHBondContact ND2-CD1 3.47Å; N371-R497 PolarHBondContact OD1-NE 2.87Å; N371-R497 PolarHBondContact OD1-NH2 3.4Å
372R96.1Very high95.7Very high154 Ų15432.3 Ų32.358%0.58117%0.166SC*.  trans-138.8-172.7172.9-69.6-169.1169.5-153.7-3.8108H367 P370 S400 T401H367-R372 PolarHBondContact CE1-O 2.69Å; P370-R372 PolarHBondContact O-N 2.78Å; R372-S400 CarbonylContact O-C 3.58Å; R372-S400 WeakPolarHBondContact O-CA 3.44Å; R372-S400 WeakPolarHBondContact O-CB 3.43Å; R372-T401 VanDerWaalsContact C-OG1 3.31Å; R372-T401 PolarHBondContact O-N 2.88Å; R372-T401 PolarHBondContact O-OG1 2.93Å
373R96.9Very high95.7Very high23 Ų2332.8 Ų32.89%0.08717%0.167CC..  trans-151.6163.317267179.8-66.3-174.8-3.2110.4Y244 Y245 Y375 N396 T401 F403Y244-R373 VanDerWaalsContact O-CZ 3.28Å; Y244-R373 PolarHBondContact O-NH1 2.66Å; Y244-R373 PolarHBondContact O-NH2 3.08Å; Y245-R373 PolarHBondContact O-NH2 3.16Å; Y245-R373 VanDerWaalsContact O-NH2 3.09Å; R373-Y375 VanDerWaalsContact CD-CE1 3.49Å; R373-Y375 WeakPolarHBondContact CD-OH 3.15Å; R373-Y375 HydrophobicContact CG-CD2 4.28Å; R373-Y375 HydrophobicContact CG-CE1 3.99Å; R373-Y375 HydrophobicContact CG-CE2 3.64Å; R373-Y375 VanDerWaalsContact CG-CZ 3.49Å; R373-N396 WeakPolarHBondContact CA-OD1 3.47Å; R373-N396 WeakPolarHBondContact CB-OD1 3.38Å; R373-T401 VanDerWaalsContact CD-O 3.3Å; R373-T401 WeakPolarHBondContact CD-O 3.44Å; R373-F403 VanDerWaalsContact NH2-CZ 3.27Å
374V95.9Very high95.6Very high16 Ų1634.8 Ų34.810%0.09718%0.177CC..  trans-96149.3162.6-67.90000110.1Y344 H367 Q394 N396Y344-V374 HydrophobicContact CD2-CB 4.35Å; Y344-V374 HydrophobicContact CD2-CG2 3.69Å; Y344-V374 HydrophobicContact CE2-CB 4.46Å; Y344-V374 HydrophobicContact CE2-CG2 3.9Å; Y344-V374 WeakPolarHBondContact CE2-O 3.21Å; H367-V374 HydrophobicContact CB-CG1 3.97Å; V374-Q394 HydrophobicContact CB-CB 4.42Å; V374-Q394 HydrophobicContact CG1-CB 4.21Å; V374-Q394 HydrophobicContact CG2-CB 4.03Å; V374-N396 WeakPolarHBondContact CG2-OD1 3.44Å; V374-N396 PolarHBondContact N-OD1 2.94Å; V374-N396 PolarHBondContact O-ND2 2.98Å
375Y93.8Very high95.5Very high52 Ų5234.8 Ų34.820%0.20418%0.177CC..  trans-115.6170177-64.6-83.2000111.3H227 Y244 R328 R373 E377H227-Y375 AromaticContact CE1-CE1 3.91Å; H227-Y375 AromaticContact CE1-CZ 3.73Å; H227-Y375 PolarHBondContact CE1-OH 2.72Å; H227-Y375 AromaticContact ND1-CE1 3.89Å; H227-Y375 AromaticContact ND1-CZ 3.88Å; H227-Y375 PolarHBondContact ND1-OH 2.94Å; Y244-Y375 AromaticContact CD1-CD1 3.7Å; Y244-Y375 HydrophobicContact CD1-CD1 3.7Å; Y244-Y375 HydrophobicContact CD1-CE1 4.3Å; Y244-Y375 HydrophobicContact CD2-CD1 4.24Å; Y244-Y375 AromaticContact CE1-CD1 3.93Å; Y244-Y375 HydrophobicContact CE1-CD1 3.93Å; Y244-Y375 HydrophobicContact CE2-CD1 4.44Å; Y244-Y375 AromaticContact CG-CD1 3.87Å; Y244-Y375 HydrophobicContact CG-CD1 3.87Å; Y244-Y375 HydrophobicContact CG-CE1 4.12Å; R328-Y375 PolarHBondContact NE-O 2.83Å; R328-Y375 PolarHBondContact NH2-O 2.75Å; R373-Y375 VanDerWaalsContact CD-CE1 3.49Å; R373-Y375 WeakPolarHBondContact CD-OH 3.15Å; R373-Y375 HydrophobicContact CG-CD2 4.28Å; R373-Y375 HydrophobicContact CG-CE1 3.99Å; R373-Y375 HydrophobicContact CG-CE2 3.64Å; R373-Y375 VanDerWaalsContact CG-CZ 3.49Å; Y375-E377 PolarHBondContact O-N 3.27Å
376W92.1Very high95.4Very high33 Ų3334.6 Ų34.613%0.12518%0.176CC..SBendtrans-83.288169.4-17179.1000109.7Y244 T247 K272 N291 D292 R328 Y344Y244-W376 PolarHBondContact OH-O 3.03Å; T247-W376 HydrophobicContact CG2-CE3 4.37Å; K272-W376 HydrophobicContact CG-CE3 4.46Å; K272-W376 HydrophobicContact CG-CZ3 3.97Å; N291-W376 HydrophobicContact CB-CH2 3.64Å; N291-W376 HydrophobicContact CB-CZ3 3.67Å; D292-W376 HydrophobicContact CB-CZ2 3.82Å; D292-W376 WeakPolarHBondContact OD1-CZ2 3.43Å; R328-W376 PolarHBondContact O-NE1 3.48Å; Y344-W376 HydrophobicContact CD1-CB 4.07Å; Y344-W376 AromaticContact CD1-CD1 3.88Å; Y344-W376 HydrophobicContact CD1-CG 4.39Å; Y344-W376 HydrophobicContact CE1-CB 3.51Å; Y344-W376 HydrophobicContact CE1-CG 4.21Å; Y344-W376 PolarHBondContact OH-N 3.17Å
377E91Very high95.1Very high87 Ų8739.2 Ų39.241%0.40720%0.201SC..SBendtrans-150.2171.7-177.364.3-168.9172.900110.9F290 Y375 S379F290-E377 HydrophobicContact CD2-CB 4.25Å; F290-E377 HydrophobicContact CE2-CB 4.26Å; Y375-E377 PolarHBondContact O-N 3.27Å; E377-S379 PolarHBondContact O-N 3.18Å
378Y93.5Very high94.9Very high51 Ų5139.5 Ų39.520%0.220%0.201CC..  trans-64.2130.4172.6171.3-90.3000110.4N291 A295 L320 L325 Q383N291-Y378 WeakPolarHBondContact O-CB 3.27Å; N291-Y378 PolarHBondContact O-N 2.87Å; A295-Y378 HydrophobicContact CB-CD1 3.66Å; A295-Y378 HydrophobicContact CB-CD2 4.05Å; A295-Y378 HydrophobicContact CB-CE1 3.77Å; A295-Y378 HydrophobicContact CB-CE2 4.12Å; A295-Y378 HydrophobicContact CB-CG 3.83Å; L320-Y378 HydrophobicContact CD1-CE2 3.93Å; L320-Y378 VanDerWaalsContact CD1-OH 3.27Å; L320-Y378 WeakPolarHBondContact CD1-OH 3.27Å; L325-Y378 HydrophobicContact CD1-CD2 4.06Å; L325-Y378 HydrophobicContact CD1-CE2 3.73Å; Y378-Q383 HydrophobicContact CD2-CG 3.98Å; Y378-Q383 HydrophobicContact CE2-CB 4.41Å; Y378-Q383 HydrophobicContact CE2-CG 3.66Å
379S94.6Very high94.7Very high29 Ų2940.3 Ų40.320%0.20321%0.209CC..  trans-127.3120.2171.4163.60000108.6E377 E381 D382 Q383E377-S379 PolarHBondContact O-N 3.18Å; S379-E381 VanDerWaalsContact C-N 3.26Å; S379-E381 PolarHBondContact O-N 2.98Å; S379-D382 WeakPolarHBondContact CB-OD1 3.23Å; S379-D382 PolarHBondContact O-N 3.02Å; S379-D382 VanDerWaalsContact OG-CG 3.29Å; S379-D382 PolarHBondContact OG-N 2.74Å; S379-D382 VanDerWaalsContact OG-N 3.15Å; S379-D382 PolarHBondContact OG-OD1 2.59Å; S379-Q383 WeakPolarHBondContact O-CB 3.11Å; S379-Q383 WeakPolarHBondContact O-CG 3.44Å; S379-Q383 PolarHBondContact O-N 2.75Å
380S94.7Very high94.8Very high76 Ų7639.2 Ų39.253%0.53120%0.197SC..Hα-helixtrans-62.3-35.9177.848.50000112.1Q383 L384S380-Q383 PolarHBondContact O-N 2.7Å; S380-L384 WeakPolarHBondContact O-CB 3.17Å; S380-L384 PolarHBondContact O-N 2.87Å
381E96Very high94.8Very high44 Ų4439.1 Ų39.121%0.20620%0.197CC..Hα-helixtrans-62.2-51.3175176.3174.585.500111V365 S379 Q383 L384 L385 M444 F579V365-E381 WeakPolarHBondContact CG1-OE1 3.29Å; S379-E381 VanDerWaalsContact C-N 3.26Å; S379-E381 PolarHBondContact O-N 2.98Å; E381-Q383 VanDerWaalsContact C-N 3.29Å; E381-Q383 PolarHBondContact O-N 2.78Å; E381-L384 PolarHBondContact O-N 2.85Å; E381-L385 HydrophobicContact CG-CD1 4.08Å; E381-L385 WeakPolarHBondContact O-CG 3.45Å; E381-L385 PolarHBondContact O-N 2.91Å; E381-M444 HydrophobicContact CG-CE 4.3Å; E381-M444 WeakPolarHBondContact OE2-CE 3.48Å; E381-F579 HydrophobicContact CB-CE1 4.41Å; E381-F579 HydrophobicContact CB-CZ 4.19Å; E381-F579 HydrophobicContact CG-CE1 3.99Å; E381-F579 HydrophobicContact CG-CZ 4.14Å
382D96.6Very high94.9Very high1 Ų138 Ų381%0.00519%0.19CC..Hα-helixtrans-61.9-40.7-180-65.934.6000111.1R328 T346 S379 L385 A386 V392 Q394R328-D382 IonicContact NH1-OD2 3.91Å; R328-D382 PolarHBondContact NH1-OD2 3.35Å; T346-D382 HydrophobicContact CG2-CB 4.33Å; T346-D382 PolarHBondContact OG1-OD2 3.25Å; S379-D382 WeakPolarHBondContact CB-OD1 3.23Å; S379-D382 PolarHBondContact O-N 3.02Å; S379-D382 VanDerWaalsContact OG-CG 3.29Å; S379-D382 PolarHBondContact OG-N 2.74Å; S379-D382 VanDerWaalsContact OG-N 3.15Å; S379-D382 PolarHBondContact OG-OD1 2.59Å; D382-L385 PolarHBondContact O-N 3.13Å; D382-A386 WeakPolarHBondContact O-CB 3.18Å; D382-A386 PolarHBondContact O-N 3.19Å; D382-V392 HydrophobicContact CB-CG1 4.32Å; D382-Q394 PolarHBondContact OD1-NE2 3.36Å; D382-Q394 PolarHBondContact OD2-OE1 2.58Å
383Q96Very high95Very high14 Ų1430.9 Ų30.97%0.06516%0.164CC..Hα-helixtrans-66.8-39.8179.6-70.3-63.8-22.700111.9D292 L325 A326 Y378 S379 S380 E381 N387D292-Q383 PolarHBondContact O-NE2 3.45Å; L325-Q383 HydrophobicContact CD2-CG 4.45Å; A326-Q383 PolarHBondContact O-NE2 3.38Å; Y378-Q383 HydrophobicContact CD2-CG 3.98Å; Y378-Q383 HydrophobicContact CE2-CB 4.41Å; Y378-Q383 HydrophobicContact CE2-CG 3.66Å; S379-Q383 WeakPolarHBondContact O-CB 3.11Å; S379-Q383 WeakPolarHBondContact O-CG 3.44Å; S379-Q383 PolarHBondContact O-N 2.75Å; S380-Q383 PolarHBondContact O-N 2.7Å; E381-Q383 VanDerWaalsContact C-N 3.29Å; E381-Q383 PolarHBondContact O-N 2.78Å; Q383-N387 WeakPolarHBondContact O-CB 3.37Å; Q383-N387 PolarHBondContact O-N 3.29Å
384L95.4Very high95.1Very high42 Ų4230.7 Ų30.722%0.2216%0.164CC..Hα-helixtrans-61.5-52.3173.9175.863.7000110.8S380 E381 A386 N387 R388 F579S380-L384 WeakPolarHBondContact O-CB 3.17Å; S380-L384 PolarHBondContact O-N 2.87Å; E381-L384 PolarHBondContact O-N 2.85Å; L384-A386 PolarHBondContact O-N 2.91Å; L384-N387 WeakPolarHBondContact O-CB 3.37Å; L384-N387 PolarHBondContact O-N 2.89Å; L384-R388 WeakPolarHBondContact O-CG 3.3Å; L384-R388 PolarHBondContact O-N 3.04Å; L384-R388 VanDerWaalsContact O-N 3.08Å; L384-F579 HydrophobicContact CD2-CB 3.88Å; L384-F579 HydrophobicContact CD2-CD1 3.54Å; L384-F579 HydrophobicContact CD2-CE1 4.27Å; L384-F579 HydrophobicContact CD2-CG 3.78Å
385L96.9Very high95.2Very high3 Ų330.1 Ų30.12%0.01616%0.161CC..Hα-helixtrans-62.4-42.1-179.4-65.1173.3000111.7I363 V365 E381 D382 N387 R388 G389 Y390 V392 M444 I582 F586I363-L385 HydrophobicContact CB-CD1 4.49Å; I363-L385 HydrophobicContact CG2-CD1 4.2Å; V365-L385 HydrophobicContact CG2-CD1 4.08Å; E381-L385 HydrophobicContact CG-CD1 4.08Å; E381-L385 WeakPolarHBondContact O-CG 3.45Å; E381-L385 PolarHBondContact O-N 2.91Å; D382-L385 PolarHBondContact O-N 3.13Å; L385-N387 VanDerWaalsContact C-N 3.34Å; L385-N387 PolarHBondContact O-N 3.14Å; L385-R388 PolarHBondContact O-N 2.57Å; L385-R388 VanDerWaalsContact O-N 3.13Å; L385-G389 PolarHBondContact O-N 3.34Å; L385-Y390 HydrophobicContact CB-CD2 4.38Å; L385-Y390 HydrophobicContact CD2-CD2 4.39Å; L385-Y390 WeakPolarHBondContact O-CB 3.18Å; L385-Y390 WeakPolarHBondContact O-CD2 3.4Å; L385-Y390 PolarHBondContact O-N 3.35Å; L385-V392 HydrophobicContact CB-CG2 3.54Å; L385-V392 HydrophobicContact CD1-CG2 4.18Å; L385-M444 HydrophobicContact CD1-SD 3.73Å; L385-I582 HydrophobicContact CD2-CG2 4.37Å; L385-F586 HydrophobicContact CD2-CD2 3.83Å; L385-F586 HydrophobicContact CD2-CE2 3.77Å
386A95.5Very high95.4Very high2 Ų227.6 Ų27.62%0.01715%0.151CC..Hα-helixtrans-67.2-34.4176.400000112.8A326 T346 P348 D382 L384 R388 G389 Y390A326-A386 HydrophobicContact CB-CB 3.5Å; T346-A386 HydrophobicContact CG2-CB 3.84Å; P348-A386 WeakPolarHBondContact CB-O 3.43Å; D382-A386 WeakPolarHBondContact O-CB 3.18Å; D382-A386 PolarHBondContact O-N 3.19Å; L384-A386 PolarHBondContact O-N 2.91Å; A386-R388 PolarHBondContact O-N 3.06Å; A386-G389 PolarHBondContact O-N 3.42Å; A386-G389 VanDerWaalsContact O-N 3.16Å; A386-Y390 WeakPolarHBondContact CA-O 3.35Å
387N93.2Very high95.7Very high103 Ų10326.1 Ų26.155%0.55115%0.145SC*.Hα-helixtrans-60.5-37.4171.4-175.3-82.4000111.4Q383 L384 L385 G389Q383-N387 WeakPolarHBondContact O-CB 3.37Å; Q383-N387 PolarHBondContact O-N 3.29Å; L384-N387 WeakPolarHBondContact O-CB 3.37Å; L384-N387 PolarHBondContact O-N 2.89Å; L385-N387 VanDerWaalsContact C-N 3.34Å; L385-N387 PolarHBondContact O-N 3.14Å; N387-G389 PolarHBondContact O-N 2.72Å
388R93.9Very high96Very high28 Ų2822.2 Ų22.211%0.10613%0.127CC..THydrogen-bonded Turntrans-75.83.5177.2-61.8-37.8-179.7-150.63.8115.4L384 L385 A386 Y390 E583 S593 E595L384-R388 WeakPolarHBondContact O-CG 3.3Å; L384-R388 PolarHBondContact O-N 3.04Å; L384-R388 VanDerWaalsContact O-N 3.08Å; L385-R388 PolarHBondContact O-N 2.57Å; L385-R388 VanDerWaalsContact O-N 3.13Å; A386-R388 PolarHBondContact O-N 3.06Å; R388-Y390 HydrophobicContact CB-CD2 3.88Å; R388-Y390 HydrophobicContact CB-CE2 3.63Å; R388-E583 HydrophobicContact CG-CG 4.4Å; R388-E583 IonicContact CZ-OE1 3.96Å; R388-E583 IonicContact CZ-OE2 3.36Å; R388-E583 IonicContact NE-OE1 3.97Å; R388-E583 PolarHBondContact NE-OE1 3.43Å; R388-E583 IonicContact NE-OE2 3.38Å; R388-E583 IonicContact NH2-OE1 2.76Å; R388-E583 PolarHBondContact NH2-OE1 2.73Å; R388-E583 IonicContact NH2-OE2 3.48Å; R388-E583 PolarHBondContact NH2-OE2 2.92Å; R388-S593 VanDerWaalsContact CA-OG 3.25Å; R388-S593 WeakPolarHBondContact CA-OG 3.42Å; R388-S593 VanDerWaalsContact CB-O 3.31Å; R388-S593 WeakPolarHBondContact CB-O 3.3Å; R388-S593 WeakPolarHBondContact CD-O 3.03Å; R388-S593 WeakPolarHBondContact CG-O 3.26Å; R388-S593 PolarHBondContact O-N 3.33Å; R388-S593 PolarHBondContact O-OG 2.93Å; R388-E595 IonicContact CZ-OE1 3.32Å; R388-E595 IonicContact NH1-OE1 2.98Å; R388-E595 PolarHBondContact NH1-OE1 3.31Å; R388-E595 IonicContact NH2-OE1 3.78Å; R388-E595 PolarHBondContact NH2-OE1 2.86Å; R388-E595 IonicContact NH2-OE2 3.08Å
389G92.4Very high96.3Very high35 Ų3519.8 Ų19.836%0.36112%0.117SC..THydrogen-bonded Turntrans94.611.2173.600000114.4P348 L385 A386 N387P348-G389 VanDerWaalsContact CG-C 3.49Å; P348-G389 WeakPolarHBondContact CG-O 3.22Å; L385-G389 PolarHBondContact O-N 3.34Å; A386-G389 PolarHBondContact O-N 3.42Å; A386-G389 VanDerWaalsContact O-N 3.16Å; N387-G389 PolarHBondContact O-N 2.72Å
390Y95.3Very high96.4Very high3 Ų318.4 Ų18.41%0.01211%0.108CC..PPolyproline II helixtrans-94.2143.7179.2-52.1-61.7000112.9P348 A361 I363 L385 A386 R388 F586 A587 L590 G592P348-Y390 WeakPolarHBondContact CD-O 3.4Å; P348-Y390 VanDerWaalsContact CG-O 3.29Å; P348-Y390 WeakPolarHBondContact CG-O 3.35Å; A361-Y390 HydrophobicContact CB-CD1 3.88Å; A361-Y390 HydrophobicContact CB-CE1 4.2Å; A361-Y390 CarbonylContact O-C 3.6Å; A361-Y390 WeakPolarHBondContact O-CA 3.48Å; I363-Y390 HydrophobicContact CD1-CD1 4.21Å; I363-Y390 HydrophobicContact CD1-CD2 4.43Å; I363-Y390 HydrophobicContact CD1-CG 4.1Å; I363-Y390 HydrophobicContact CG1-CD1 4.4Å; I363-Y390 HydrophobicContact CG1-CD2 4.22Å; I363-Y390 HydrophobicContact CG1-CG 3.87Å; L385-Y390 HydrophobicContact CB-CD2 4.38Å; L385-Y390 HydrophobicContact CD2-CD2 4.39Å; L385-Y390 WeakPolarHBondContact O-CB 3.18Å; L385-Y390 WeakPolarHBondContact O-CD2 3.4Å; L385-Y390 PolarHBondContact O-N 3.35Å; A386-Y390 WeakPolarHBondContact CA-O 3.35Å; R388-Y390 HydrophobicContact CB-CD2 3.88Å; R388-Y390 HydrophobicContact CB-CE2 3.63Å; Y390-F586 HydrophobicContact CE2-CB 3.97Å; Y390-F586 HydrophobicContact CE2-CD2 4.39Å; Y390-F586 VanDerWaalsContact OH-CB 3.26Å; Y390-F586 WeakPolarHBondContact OH-CB 3.35Å; Y390-F586 PolarHBondContact OH-O 3.38Å; Y390-F586 VanDerWaalsContact OH-O 3.13Å; Y390-A587 PolarHBondContact OH-N 2.96Å; Y390-L590 HydrophobicContact CD1-CD1 4.18Å; Y390-L590 HydrophobicContact CE1-CB 3.8Å; Y390-L590 HydrophobicContact CE1-CD1 3.86Å; Y390-G592 VanDerWaalsContact OH-CA 3.26Å; Y390-G592 WeakPolarHBondContact OH-CA 3.17Å; Y390-G592 PolarHBondContact OH-N 2.91Å
391V95.8Very high96.6Very high1 Ų117 Ų171%0.00610%0.096CC..EExtended strand (participates in β ladder)trans-80126.8161.3169.70000108.3L345 T346 M347 P348 P360 A361 G362 I363 V436L345-V391 HydrophobicContact CD1-CG1 3.51Å; L345-V391 HydrophobicContact CD2-CG1 4.24Å; L345-V391 HydrophobicContact CG-CG1 3.71Å; T346-V391 WeakPolarHBondContact O-CA 3.39Å; M347-V391 HydrophobicContact CE-CG2 3.56Å; M347-V391 HydrophobicContact SD-CB 4.37Å; M347-V391 HydrophobicContact SD-CG1 3.84Å; M347-V391 HydrophobicContact SD-CG2 3.61Å; P348-V391 HydrophobicContact CG-CG2 4.41Å; P360-V391 HydrophobicContact CB-CG2 3.97Å; P360-V391 HydrophobicContact CG-CB 4.36Å; P360-V391 HydrophobicContact CG-CG2 3.27Å; A361-V391 PolarHBondContact O-N 3.22Å; G362-V391 CarbonylContact C-O 3.56Å; G362-V391 VanDerWaalsContact CA-O 3.31Å; G362-V391 WeakPolarHBondContact CA-O 3.48Å; I363-V391 PolarHBondContact N-O 3.31Å; V391-V436 HydrophobicContact CB-CG1 3.55Å; V391-V436 HydrophobicContact CG1-CG1 3.58Å; V391-V436 HydrophobicContact CG2-CG1 4.1Å
392V97.7Very high96.6Very high0 Ų015.3 Ų15.30%09%0.09CC..EExtended strand (participates in β ladder)trans-101.8125.3177.8-172.10000108.6L345 T346 V365 D382 L385L345-V392 CarbonylContact C-O 3.6Å; L345-V392 WeakPolarHBondContact CA-O 3.47Å; T346-V392 PolarHBondContact N-O 3.17Å; T346-V392 PolarHBondContact O-N 2.84Å; V365-V392 HydrophobicContact CB-CG1 4.21Å; V365-V392 HydrophobicContact CG2-CG1 3.52Å; D382-V392 HydrophobicContact CB-CG1 4.32Å; L385-V392 HydrophobicContact CB-CG2 3.54Å; L385-V392 HydrophobicContact CD1-CG2 4.18Å
393L98Very high96.6Very high6 Ų615.9 Ų15.93%0.0319%0.093CC..EExtended strand (participates in β ladder)trans-112.4122.5176.2179.965.5000109C343 L345 I363 N364 V365 A426 A430C343-L393 HydrophobicContact CB-CD1 4Å; L345-L393 HydrophobicContact CD1-CB 4.12Å; L345-L393 HydrophobicContact CD1-CD1 3.65Å; L345-L393 HydrophobicContact CD1-CG 4.44Å; I363-L393 PolarHBondContact O-N 3.46Å; N364-L393 PolarHBondContact OD1-O 2.9Å; V365-L393 PolarHBondContact N-O 3.4Å; L393-A426 HydrophobicContact CD2-CB 4.06Å; L393-A430 HydrophobicContact CD2-CB 4.3Å
394Q97.9Very high96.7Very high18 Ų1815.3 Ų15.38%0.0849%0.09CC..EExtended strand (participates in β ladder)trans-123.2126.6172-73.1-178.6-29.600109.2R328 C343 Y344 V365 V374 D382R328-Q394 VanDerWaalsContact CZ-OE1 3.28Å; C343-Q394 CarbonylContact C-O 3.51Å; C343-Q394 VanDerWaalsContact CA-O 3.29Å; C343-Q394 WeakPolarHBondContact CA-O 3.46Å; Y344-Q394 PolarHBondContact N-O 3.34Å; Y344-Q394 PolarHBondContact O-N 3.25Å; V365-Q394 HydrophobicContact CB-CG 3.76Å; V365-Q394 HydrophobicContact CG1-CG 4.03Å; V374-Q394 HydrophobicContact CB-CB 4.42Å; V374-Q394 HydrophobicContact CG1-CB 4.21Å; V374-Q394 HydrophobicContact CG2-CB 4.03Å; D382-Q394 PolarHBondContact OD1-NE2 3.36Å; D382-Q394 PolarHBondContact OD2-OE1 2.58Å
395C98.1Very high96.8Very high4 Ų414.5 Ų14.53%0.0279%0.085CC..EExtended strand (participates in β ladder)trans-127.5144.1-176.7-66.50000112.3C343 H367 F397 A426C343-C395 HydrophobicContact CB-CB 4.1Å; C343-C395 WeakPolarHBondContact CB-SG 3.31Å; C343-C395 WeakPolarHBondContact SG-CB 3.45Å; C343-C395 CovalentContact SG-SG 2.03Å; C343-C395 PolarHBondContact SG-SG 3.23Å; H367-C395 PolarHBondContact CD2-O 3.16Å; C395-F397 WeakPolarHBondContact O-CD1 3.41Å; C395-F397 PolarHBondContact O-N 3.45Å; C395-A426 HydrophobicContact CB-CB 4.21Å; C395-A426 WeakPolarHBondContact SG-CB 3.33Å
396N98.3Very high96.8Very high0 Ų018.6 Ų18.60%010%0.104CC..EExtended strand (participates in β ladder)trans-88.884169.4-64.3-56.7000109.1Q341 L342 R373 V374 S400 F403 F407Q341-N396 VanDerWaalsContact CB-O 3.26Å; Q341-N396 WeakPolarHBondContact CB-O 3.46Å; L342-N396 WeakPolarHBondContact O-CB 3.21Å; L342-N396 PolarHBondContact O-N 2.91Å; L342-N396 PolarHBondContact O-ND2 3.34Å; R373-N396 WeakPolarHBondContact CA-OD1 3.47Å; R373-N396 WeakPolarHBondContact CB-OD1 3.38Å; V374-N396 WeakPolarHBondContact CG2-OD1 3.44Å; V374-N396 PolarHBondContact N-OD1 2.94Å; V374-N396 PolarHBondContact O-ND2 2.98Å; N396-S400 VanDerWaalsContact C-OG 3.3Å; N396-S400 WeakPolarHBondContact CA-OG 3.28Å; N396-F403 HydrophobicContact CB-CD2 4.48Å; N396-F403 HydrophobicContact CB-CE2 3.52Å; N396-F403 HydrophobicContact CB-CZ 3.86Å; N396-F407 VanDerWaalsContact O-CZ 3.29Å; N396-F407 WeakPolarHBondContact O-CZ 3.18Å
397F98.5Very high96.9Very high1 Ų119.5 Ų19.50%0.00411%0.108CC..  trans-68.8166.6176.547.6-94.6000111.7I366 H367 P370 C395 G399 S400 F407 M419 D422 I423 Y448I366-F397 HydrophobicContact CG2-CD1 4.43Å; I366-F397 HydrophobicContact CG2-CE1 3.62Å; I366-F397 HydrophobicContact CG2-CZ 4.2Å; H367-F397 AromaticContact CD2-CE1 3.7Å; H367-F397 AromaticContact CE1-CE1 3.71Å; H367-F397 AromaticContact CE1-CE2 3.96Å; H367-F397 AromaticContact CE1-CZ 3.3Å; H367-F397 WeakPolarHBondContact CE1-CZ 3.27Å; H367-F397 AromaticContact ND1-CZ 3.82Å; H367-F397 AromaticContact NE2-CE1 3.38Å; H367-F397 WeakPolarHBondContact NE2-CE1 3.44Å; H367-F397 AromaticContact NE2-CZ 3.49Å; H367-F397 WeakPolarHBondContact NE2-CZ 3.46Å; P370-F397 HydrophobicContact CB-CE2 3.92Å; P370-F397 HydrophobicContact CB-CZ 4.45Å; C395-F397 WeakPolarHBondContact O-CD1 3.41Å; C395-F397 PolarHBondContact O-N 3.45Å; F397-G399 PolarHBondContact O-N 3.48Å; F397-S400 PolarHBondContact N-OG 2.85Å; F397-S400 VanDerWaalsContact O-CB 3.29Å; F397-S400 WeakPolarHBondContact O-CB 3.19Å; F397-S400 PolarHBondContact O-N 2.86Å; F397-S400 PolarHBondContact O-OG 3.13Å; F397-F407 WeakPolarHBondContact O-CE1 3.32Å; F397-M419 HydrophobicContact CD2-CB 4.47Å; F397-M419 HydrophobicContact CD2-CE 3.66Å; F397-M419 HydrophobicContact CE2-CE 3.46Å; F397-M419 VanDerWaalsContact CE2-CE 3.46Å; F397-D422 HydrophobicContact CB-CB 3.66Å; F397-I423 HydrophobicContact CB-CG1 4.4Å; F397-I423 HydrophobicContact CD1-CD1 4.16Å; F397-I423 HydrophobicContact CD1-CG1 3.86Å; F397-I423 HydrophobicContact CE1-CD1 4.39Å; F397-I423 HydrophobicContact CG-CG1 4.22Å; F397-Y448 HydrophobicContact CD2-CE1 4.31Å; F397-Y448 HydrophobicContact CE1-CE1 4.16Å; F397-Y448 HydrophobicContact CE2-CD1 4.02Å; F397-Y448 AromaticContact CE2-CE1 3.39Å; F397-Y448 HydrophobicContact CE2-CE1 3.39Å; F397-Y448 AromaticContact CZ-CD1 3.64Å; F397-Y448 HydrophobicContact CZ-CD1 3.64Å; F397-Y448 AromaticContact CZ-CE1 3.29Å; F397-Y448 HydrophobicContact CZ-CE1 3.29Å
398R98.5Very high97.1Very high5 Ų514.7 Ų14.72%0.0198%0.082CC..THydrogen-bonded Turntrans-52.2137.2178.675.2-171.767.3-151.8-1.8111.6D337 L339 A410 M419 D422D337-R398 IonicContact OD1-CZ 3.18Å; D337-R398 IonicContact OD1-NH1 3.88Å; D337-R398 IonicContact OD1-NH2 2.99Å; D337-R398 PolarHBondContact OD1-NH2 3.06Å; D337-R398 IonicContact OD2-CZ 3.98Å; D337-R398 IonicContact OD2-NH1 3.53Å; D337-R398 PolarHBondContact OD2-NH1 3.09Å; D337-R398 IonicContact OD2-NH2 2.74Å; D337-R398 PolarHBondContact OD2-NH2 2.62Å; L339-R398 HydrophobicContact CD2-CB 3.57Å; R398-A410 HydrophobicContact CB-CB 4Å; R398-A410 WeakPolarHBondContact CD-O 3.24Å; R398-M419 HydrophobicContact CG-CB 4.4Å; R398-M419 HydrophobicContact CG-CG 3.62Å; R398-M419 WeakPolarHBondContact O-CE 3.46Å; R398-M419 WeakPolarHBondContact O-CG 3.39Å; R398-D422 WeakPolarHBondContact CB-OD2 3.4Å; R398-D422 WeakPolarHBondContact CG-OD2 3.49Å; R398-D422 IonicContact CZ-OD1 3.22Å; R398-D422 VanDerWaalsContact CZ-OD1 3.27Å; R398-D422 IonicContact CZ-OD2 3.75Å; R398-D422 PolarHBondContact N-OD2 3.49Å; R398-D422 VanDerWaalsContact NE-CG 3.27Å; R398-D422 IonicContact NE-OD1 2.83Å; R398-D422 PolarHBondContact NE-OD1 3.13Å; R398-D422 VanDerWaalsContact NE-OD1 3.08Å; R398-D422 IonicContact NE-OD2 3.54Å; R398-D422 PolarHBondContact NE-OD2 3.27Å; R398-D422 IonicContact NH2-OD1 2.75Å; R398-D422 PolarHBondContact NH2-OD1 3.12Å; R398-D422 IonicContact NH2-OD2 2.66Å
399G98Very high97.3Very high0 Ų014.4 Ų14.40%09%0.085CC..THydrogen-bonded Turntrans94.5-10.3-17000000114.9N371 F397 F407 L408N371-G399 WeakPolarHBondContact CA-O 3.49Å; N371-G399 PolarHBondContact ND2-O 3.42Å; F397-G399 PolarHBondContact O-N 3.48Å; G399-F407 PolarHBondContact N-O 3.08Å; G399-L408 WeakPolarHBondContact CA-O 3.45Å; G399-L408 WeakPolarHBondContact O-CD1 3.43Å
400S98.4Very high97.6Very high0 Ų013.9 Ų13.90%08%0.078CC..  trans-66.3150.9169.2-54.50000111.3H367 R372 N396 F397 F407H367-S400 PolarHBondContact NE2-OG 3.27Å; H367-S400 VanDerWaalsContact NE2-OG 3.17Å; R372-S400 CarbonylContact O-C 3.58Å; R372-S400 WeakPolarHBondContact O-CA 3.44Å; R372-S400 WeakPolarHBondContact O-CB 3.43Å; N396-S400 VanDerWaalsContact C-OG 3.3Å; N396-S400 WeakPolarHBondContact CA-OG 3.28Å; F397-S400 PolarHBondContact N-OG 2.85Å; F397-S400 VanDerWaalsContact O-CB 3.29Å; F397-S400 WeakPolarHBondContact O-CB 3.19Å; F397-S400 PolarHBondContact O-N 2.86Å; F397-S400 PolarHBondContact O-OG 3.13Å; S400-F407 WeakPolarHBondContact O-CD1 3.49Å
401T97.4Very high97.8Very high47 Ų4714 Ų1429%0.2888%0.079SC..SBendtrans-80.1165.1175.251.80000111.3N371 R372 R373 F403 L408N371-T401 HydrophobicContact CB-CG2 4.32Å; N371-T401 WeakPolarHBondContact O-CG2 3.32Å; R372-T401 VanDerWaalsContact C-OG1 3.31Å; R372-T401 PolarHBondContact O-N 2.88Å; R372-T401 PolarHBondContact O-OG1 2.93Å; R373-T401 VanDerWaalsContact CD-O 3.3Å; R373-T401 WeakPolarHBondContact CD-O 3.44Å; T401-F403 WeakPolarHBondContact O-CD2 3.45Å; T401-F403 VanDerWaalsContact O-CE2 3.27Å; T401-F403 WeakPolarHBondContact O-CE2 3.41Å; T401-L408 HydrophobicContact CG2-CD1 4.11Å
402G96.6Very high97.9Very high8 Ų815.6 Ų15.68%0.0829%0.087CC..SBendtrans97.1-6.2168.500000115.2S224 D225S224-G402 VanDerWaalsContact CB-O 3.3Å; S224-G402 WeakPolarHBondContact CB-O 3.44Å; D225-G402 VanDerWaalsContact CG-C 3.46Å; D225-G402 PolarHBondContact N-O 3.33Å; D225-G402 WeakPolarHBondContact OD2-CA 3.46Å; D225-G402 PolarHBondContact OD2-N 2.85Å
403F97Very high97.9Very high14 Ų1416.5 Ų16.56%0.06110%0.096CC..SBendtrans-1198.3-173-55.3-77.7000113.5K202 D225 Y245 L342 R373 N396 T401 F407K202-F403 PolarHBondContact NZ-O 3.25Å; K202-F403 VanDerWaalsContact NZ-O 3.12Å; D225-F403 PolarHBondContact OD2-N 3.49Å; D225-F403 VanDerWaalsContact OD2-N 3.16Å; Y245-F403 HydrophobicContact CD2-CD1 4Å; Y245-F403 AromaticContact CD2-CE1 3.93Å; Y245-F403 HydrophobicContact CD2-CE1 3.93Å; Y245-F403 AromaticContact CE2-CD1 3.84Å; Y245-F403 HydrophobicContact CE2-CD1 3.84Å; Y245-F403 AromaticContact CE2-CE1 3.9Å; Y245-F403 HydrophobicContact CE2-CE1 3.9Å; L342-F403 HydrophobicContact CB-CE1 3.96Å; L342-F403 HydrophobicContact CB-CZ 3.98Å; L342-F403 HydrophobicContact CD2-CE1 3.94Å; L342-F403 HydrophobicContact CD2-CZ 4.03Å; R373-F403 VanDerWaalsContact NH2-CZ 3.27Å; N396-F403 HydrophobicContact CB-CD2 4.48Å; N396-F403 HydrophobicContact CB-CE2 3.52Å; N396-F403 HydrophobicContact CB-CZ 3.86Å; T401-F403 WeakPolarHBondContact O-CD2 3.45Å; T401-F403 VanDerWaalsContact O-CE2 3.27Å; T401-F403 WeakPolarHBondContact O-CE2 3.41Å; F403-F407 HydrophobicContact CB-CB 3.81Å; F403-F407 HydrophobicContact CB-CD1 3.84Å; F403-F407 HydrophobicContact CB-CD2 4.11Å; F403-F407 HydrophobicContact CB-CE1 4.46Å; F403-F407 HydrophobicContact CB-CG 3.64Å; F403-F407 AromaticContact CD2-CD1 3.99Å; F403-F407 HydrophobicContact CD2-CD1 3.99Å; F403-F407 AromaticContact CD2-CE1 3.96Å; F403-F407 HydrophobicContact CD2-CE1 3.96Å; F403-F407 HydrophobicContact CG-CD1 4.27Å; F403-F407 HydrophobicContact CG-CE1 4.45Å; F403-F407 HydrophobicContact CG-CG 4.43Å
404G97.2Very high97.9Very high1 Ų118 Ų181%0.0110%0.103CC..  trans104.2159.7-176.800000113.8D201 D225 E406 F407 L408D201-G404 CarbonylContact O-C 3.44Å; D201-G404 VanDerWaalsContact O-CA 3.25Å; D201-G404 WeakPolarHBondContact O-CA 3.35Å; D225-G404 WeakPolarHBondContact OD1-CA 3.32Å; D225-G404 PolarHBondContact OD1-N 3.25Å; D225-G404 VanDerWaalsContact OD1-N 3.13Å; D225-G404 PolarHBondContact OD2-N 3.06Å; G404-E406 VanDerWaalsContact C-N 3.29Å; G404-E406 PolarHBondContact O-N 3.34Å; G404-F407 PolarHBondContact O-N 3.37Å; G404-L408 PolarHBondContact O-N 3.03Å
405K97.4Very high97.9Very high25 Ų2518 Ų1811%0.10910%0.102CC..Hα-helixtrans-65.2-29.9-176.564.2167.4178.5-89.90113.1K175 V176 S197 T200 D201 A409K175-K405 HydrophobicContact CD-CD 4.48Å; K175-K405 WeakPolarHBondContact O-CB 3.2Å; V176-K405 HydrophobicContact CG2-CD 3.86Å; S197-K405 WeakPolarHBondContact O-CD 3.37Å; S197-K405 PolarHBondContact O-NZ 3.39Å; T200-K405 VanDerWaalsContact C-NZ 3.32Å; T200-K405 PolarHBondContact O-NZ 3.16Å; D201-K405 PolarHBondContact O-N 3.16Å; D201-K405 PolarHBondContact OD1-N 3.31Å; K405-A409 WeakPolarHBondContact O-CB 3.36Å; K405-A409 PolarHBondContact O-N 3.39Å
406E97.5Very high97.7Very high90 Ų9018.1 Ų18.142%0.42110%0.104SC..Hα-helixtrans-73.9-37.1178.2-59.9-49.2137.900110.9K175 D201 G404 A409 A410K175-E406 VanDerWaalsContact NZ-CD 3.26Å; K175-E406 IonicContact NZ-OE1 3.13Å; K175-E406 PolarHBondContact NZ-OE1 2.99Å; K175-E406 IonicContact NZ-OE2 2.65Å; K175-E406 PolarHBondContact NZ-OE2 2.8Å; D201-E406 WeakPolarHBondContact OD1-CG 3.34Å; D201-E406 PolarHBondContact OD1-N 3.45Å; G404-E406 VanDerWaalsContact C-N 3.29Å; G404-E406 PolarHBondContact O-N 3.34Å; E406-A409 PolarHBondContact O-N 3.46Å; E406-A410 VanDerWaalsContact O-CB 3.32Å; E406-A410 WeakPolarHBondContact O-CB 3.31Å; E406-A410 PolarHBondContact O-N 3.45Å
407F98.1Very high97.7Very high20 Ų2019.4 Ų19.49%0.08812%0.117CC..Hα-helixtrans-64.5-42172.8-166.2-83.1000111.6L339 I340 N396 F397 G399 S400 F403 G404 A410L339-F407 HydrophobicContact CD1-CD2 3.92Å; L339-F407 HydrophobicContact CD1-CE2 3.99Å; L339-F407 HydrophobicContact CD2-CD2 4.28Å; L339-F407 HydrophobicContact CD2-CE2 3.72Å; L339-F407 HydrophobicContact CD2-CZ 4.24Å; L339-F407 HydrophobicContact CG-CD2 4.34Å; L339-F407 HydrophobicContact CG-CE2 3.89Å; I340-F407 WeakPolarHBondContact O-CE2 3.1Å; N396-F407 VanDerWaalsContact O-CZ 3.29Å; N396-F407 WeakPolarHBondContact O-CZ 3.18Å; F397-F407 WeakPolarHBondContact O-CE1 3.32Å; G399-F407 PolarHBondContact N-O 3.08Å; S400-F407 WeakPolarHBondContact O-CD1 3.49Å; F403-F407 HydrophobicContact CB-CB 3.81Å; F403-F407 HydrophobicContact CB-CD1 3.84Å; F403-F407 HydrophobicContact CB-CD2 4.11Å; F403-F407 HydrophobicContact CB-CE1 4.46Å; F403-F407 HydrophobicContact CB-CG 3.64Å; F403-F407 AromaticContact CD2-CD1 3.99Å; F403-F407 HydrophobicContact CD2-CD1 3.99Å; F403-F407 AromaticContact CD2-CE1 3.96Å; F403-F407 HydrophobicContact CD2-CE1 3.96Å; F403-F407 HydrophobicContact CG-CD1 4.27Å; F403-F407 HydrophobicContact CG-CE1 4.45Å; F403-F407 HydrophobicContact CG-CG 4.43Å; G404-F407 PolarHBondContact O-N 3.37Å; F407-A410 PolarHBondContact O-N 3.18Å
408L98.1Very high97.7Very high3 Ų324.3 Ų24.32%0.01614%0.135CC..Hα-helixtrans-62.3-47.1174179.768.4000111.9M178 T179 N371 G399 T401 G404 A410 G411 F412M178-L408 HydrophobicContact CB-CD2 4.21Å; T179-L408 HydrophobicContact CG2-CD2 3.59Å; N371-L408 HydrophobicContact CB-CD1 3.96Å; N371-L408 WeakPolarHBondContact ND2-CD1 3.47Å; G399-L408 WeakPolarHBondContact CA-O 3.45Å; G399-L408 WeakPolarHBondContact O-CD1 3.43Å; T401-L408 HydrophobicContact CG2-CD1 4.11Å; G404-L408 PolarHBondContact O-N 3.03Å; L408-A410 VanDerWaalsContact C-N 3.29Å; L408-A410 PolarHBondContact O-N 3.04Å; L408-G411 PolarHBondContact O-N 2.86Å; L408-F412 HydrophobicContact CG-CE1 4.32Å; L408-F412 HydrophobicContact CG-CZ 4.33Å
409A98.1Very high97.7Very high21 Ų2124 Ų2417%0.17414%0.135CC..Hα-helixtrans-70.2-25.9-178.300000112.8K175 K405 E406 G411 F412K175-A409 HydrophobicContact CB-CB 3.79Å; K175-A409 HydrophobicContact CD-CB 3.72Å; K175-A409 HydrophobicContact CG-CB 4.42Å; K405-A409 WeakPolarHBondContact O-CB 3.36Å; K405-A409 PolarHBondContact O-N 3.39Å; E406-A409 PolarHBondContact O-N 3.46Å; A409-G411 PolarHBondContact O-N 2.93Å; A409-G411 VanDerWaalsContact O-N 3.11Å; A409-F412 HydrophobicContact CB-CD2 4.12Å; A409-F412 HydrophobicContact CB-CE2 4.11Å; A409-F412 WeakPolarHBondContact O-CB 3.4Å; A409-F412 WeakPolarHBondContact O-CG 3.22Å; A409-F412 PolarHBondContact O-N 3.46Å
410A98.3Very high97.7Very high25 Ų2524.2 Ų24.221%0.20714%0.135CC..THydrogen-bonded Turntrans-62.7-15.417800000113.7R398 E406 F407 L408R398-A410 HydrophobicContact CB-CB 4Å; R398-A410 WeakPolarHBondContact CD-O 3.24Å; E406-A410 VanDerWaalsContact O-CB 3.32Å; E406-A410 WeakPolarHBondContact O-CB 3.31Å; E406-A410 PolarHBondContact O-N 3.45Å; F407-A410 PolarHBondContact O-N 3.18Å; L408-A410 VanDerWaalsContact C-N 3.29Å; L408-A410 PolarHBondContact O-N 3.04Å
411G98.2Very high97.7Very high4 Ų426.5 Ų26.54%0.04115%0.147CC..THydrogen-bonded Turntrans-92.5-5.8171.900000115.2L408 A409 G413 E414L408-G411 PolarHBondContact O-N 2.86Å; A409-G411 PolarHBondContact O-N 2.93Å; A409-G411 VanDerWaalsContact O-N 3.11Å; G411-G413 PolarHBondContact O-N 3.15Å; G411-E414 PolarHBondContact O-N 2.89Å
412F98Very high97.7Very high36 Ų3624.2 Ų24.216%0.15813%0.134CC..THydrogen-bonded Turntrans-69.7124.8-178.8-65.3-8.1000110.8A174 K175 M178 L408 A409 E414 V496 R497A174-F412 HydrophobicContact CB-CE2 4.4Å; K175-F412 HydrophobicContact CB-CE2 3.82Å; K175-F412 HydrophobicContact CB-CZ 4.29Å; M178-F412 HydrophobicContact SD-CE1 4.24Å; M178-F412 HydrophobicContact SD-CZ 3.85Å; L408-F412 HydrophobicContact CG-CE1 4.32Å; L408-F412 HydrophobicContact CG-CZ 4.33Å; A409-F412 HydrophobicContact CB-CD2 4.12Å; A409-F412 HydrophobicContact CB-CE2 4.11Å; A409-F412 WeakPolarHBondContact O-CB 3.4Å; A409-F412 WeakPolarHBondContact O-CG 3.22Å; A409-F412 PolarHBondContact O-N 3.46Å; F412-E414 VanDerWaalsContact C-N 3.26Å; F412-E414 PolarHBondContact O-N 2.94Å; F412-V496 HydrophobicContact CD2-CG1 3.63Å; F412-V496 HydrophobicContact CE2-CG1 4.02Å; F412-V496 HydrophobicContact CG-CG1 4.28Å; F412-R497 HydrophobicContact CD1-CG 4.08Å; F412-R497 HydrophobicContact CE1-CG 3.9Å; F412-R497 HydrophobicContact CZ-CG 4.48Å
413G97.5Very high97.8Very high18 Ų1823.9 Ų23.919%0.18613%0.13CC..THydrogen-bonded Turntrans74.99.8-176.600000115G411 R497G411-G413 PolarHBondContact O-N 3.15Å; G413-R497 PolarHBondContact N-O 3.22Å
414E98.2Very high97.8Very high39 Ų3923.4 Ų23.418%0.18213%0.128CC..  trans-110.417.6-170.5-66.1-72.3178.800113.7G411 F412 G416 G417 R418 M419G411-E414 PolarHBondContact O-N 2.89Å; F412-E414 VanDerWaalsContact C-N 3.26Å; F412-E414 PolarHBondContact O-N 2.94Å; E414-G416 PolarHBondContact O-N 2.86Å; E414-G417 CarbonylContact O-C 3.49Å; E414-G417 WeakPolarHBondContact O-CA 3.46Å; E414-G417 PolarHBondContact O-N 2.82Å; E414-R418 VanDerWaalsContact CD-NE 3.31Å; E414-R418 IonicContact OE1-CZ 3.93Å; E414-R418 VanDerWaalsContact OE1-CZ 3.22Å; E414-R418 IonicContact OE1-NE 2.73Å; E414-R418 PolarHBondContact OE1-NE 2.77Å; E414-R418 IonicContact OE1-NH2 2.79Å; E414-R418 PolarHBondContact OE1-NH2 3.12Å; E414-R418 WeakPolarHBondContact OE2-CB 3.29Å; E414-R418 WeakPolarHBondContact OE2-CG 3.44Å; E414-R418 PolarHBondContact OE2-N 2.96Å; E414-R418 IonicContact OE2-NE 3.33Å; E414-M419 HydrophobicContact CB-CG 3.7Å; E414-M419 HydrophobicContact CB-SD 4.03Å; E414-M419 WeakPolarHBondContact O-CB 3.41Å
415W97.8Very high97.8Very high16 Ų1624.4 Ų24.46%0.06113%0.133CC..THydrogen-bonded Turntrans-62.3119.6171.8-76.947.3000110P370 G417 Y448 F451 P473 L476 F498P370-W415 VanDerWaalsContact CD-CZ2 3.41Å; P370-W415 HydrophobicContact CG-CZ2 4.13Å; W415-G417 PolarHBondContact O-N 3.17Å; W415-Y448 AromaticContact CD1-CE2 3.99Å; W415-Y448 AromaticContact CD2-CD2 3.64Å; W415-Y448 HydrophobicContact CD2-CD2 3.64Å; W415-Y448 AromaticContact CD2-CE2 3.61Å; W415-Y448 HydrophobicContact CD2-CE2 3.61Å; W415-Y448 AromaticContact CE2-CD2 3.49Å; W415-Y448 VanDerWaalsContact CE2-CD2 3.49Å; W415-Y448 AromaticContact CE2-CE2 3.74Å; W415-Y448 AromaticContact CE3-CD2 3.8Å; W415-Y448 HydrophobicContact CE3-CD2 3.8Å; W415-Y448 HydrophobicContact CE3-CE2 4.03Å; W415-Y448 HydrophobicContact CG-CD2 4.35Å; W415-Y448 AromaticContact CG-CE2 3.84Å; W415-Y448 HydrophobicContact CG-CE2 3.84Å; W415-Y448 AromaticContact CH2-CD2 3.77Å; W415-Y448 HydrophobicContact CH2-CD2 3.77Å; W415-Y448 AromaticContact CZ2-CD2 3.6Å; W415-Y448 HydrophobicContact CZ2-CD2 3.6Å; W415-Y448 HydrophobicContact CZ2-CE2 4.33Å; W415-Y448 AromaticContact CZ3-CD2 3.85Å; W415-Y448 HydrophobicContact CZ3-CD2 3.85Å; W415-Y448 AromaticContact NE1-CE2 3.93Å; W415-F451 HydrophobicContact CB-CE1 3.94Å; W415-F451 HydrophobicContact CB-CZ 3.86Å; W415-F451 HydrophobicContact CD2-CD1 4.49Å; W415-F451 HydrophobicContact CD2-CE1 4.45Å; W415-F451 HydrophobicContact CE3-CB 4.43Å; W415-F451 AromaticContact CE3-CD1 3.77Å; W415-F451 HydrophobicContact CE3-CD1 3.77Å; W415-F451 AromaticContact CE3-CD2 3.84Å; W415-F451 HydrophobicContact CE3-CD2 3.84Å; W415-F451 AromaticContact CE3-CE1 3.97Å; W415-F451 HydrophobicContact CE3-CE1 3.97Å; W415-F451 AromaticContact CE3-CE2 4Å; W415-F451 HydrophobicContact CE3-CE2 4Å; W415-F451 AromaticContact CE3-CG 3.74Å; W415-F451 HydrophobicContact CE3-CG 3.74Å; W415-F451 HydrophobicContact CE3-CZ 4.09Å; W415-F451 HydrophobicContact CG-CE1 4.47Å; W415-F451 HydrophobicContact CZ3-CB 4.19Å; W415-F451 HydrophobicContact CZ3-CD1 4.35Å; W415-F451 HydrophobicContact CZ3-CD2 4.19Å; W415-F451 AromaticContact CZ3-CG 3.99Å; W415-F451 HydrophobicContact CZ3-CG 3.99Å; W415-P473 HydrophobicContact CZ3-CB 4.24Å; W415-P473 HydrophobicContact CZ3-CG 4.22Å; W415-L476 HydrophobicContact CB-CD1 4.32Å; W415-L476 HydrophobicContact CE3-CD1 4.15Å; W415-L476 HydrophobicContact CE3-CD2 3.84Å; W415-L476 HydrophobicContact CZ3-CD2 3.9Å; W415-F498 HydrophobicContact CE3-CE1 4.4Å; W415-F498 HydrophobicContact CH2-CE1 4.27Å; W415-F498 AromaticContact CH2-CZ 3.9Å; W415-F498 HydrophobicContact CH2-CZ 3.9Å; W415-F498 HydrophobicContact CZ2-CE1 4.42Å; W415-F498 HydrophobicContact CZ2-CE2 4.32Å; W415-F498 AromaticContact CZ2-CZ 3.98Å; W415-F498 HydrophobicContact CZ2-CZ 3.98Å; W415-F498 HydrophobicContact CZ3-CE1 4.26Å; W415-F498 HydrophobicContact CZ3-CZ 4.33Å
416G95.4Very high97.8Very high8 Ų823.2 Ų23.28%0.08213%0.128CC..THydrogen-bonded Turntrans74.2-5.1-172.400000114.2E414 Y455E414-G416 PolarHBondContact O-N 2.86Å; G416-Y455 VanDerWaalsContact CA-CE2 3.47Å; G416-Y455 WeakPolarHBondContact O-CE1 3.47Å; G416-Y455 PolarHBondContact O-OH 3.34Å
417G97Very high97.6Very high26 Ų2620.1 Ų20.127%0.26811%0.113SC..THydrogen-bonded Turntrans-94.1-129.7174.200000111.3E414 W415 M419 Q420 D421E414-G417 CarbonylContact O-C 3.49Å; E414-G417 WeakPolarHBondContact O-CA 3.46Å; E414-G417 PolarHBondContact O-N 2.82Å; W415-G417 PolarHBondContact O-N 3.17Å; G417-M419 PolarHBondContact O-N 3.17Å; G417-Q420 WeakPolarHBondContact O-CB 3.21Å; G417-Q420 PolarHBondContact O-N 3.05Å; G417-D421 PolarHBondContact O-N 3.22Å
418R98.2Very high97.4Very high104 Ų10421 Ų2139%0.39212%0.124SC..Hα-helixtrans-63.7-24.5-174.3-66-176.8-68.3158.6-1.7113.8D337 E414 Q420 D421 D422D337-R418 IonicContact OD2-NH1 2.66Å; E414-R418 VanDerWaalsContact CD-NE 3.31Å; E414-R418 IonicContact OE1-CZ 3.93Å; E414-R418 VanDerWaalsContact OE1-CZ 3.22Å; E414-R418 IonicContact OE1-NE 2.73Å; E414-R418 PolarHBondContact OE1-NE 2.77Å; E414-R418 IonicContact OE1-NH2 2.79Å; E414-R418 PolarHBondContact OE1-NH2 3.12Å; E414-R418 WeakPolarHBondContact OE2-CB 3.29Å; E414-R418 WeakPolarHBondContact OE2-CG 3.44Å; E414-R418 PolarHBondContact OE2-N 2.96Å; E414-R418 IonicContact OE2-NE 3.33Å; R418-Q420 VanDerWaalsContact C-N 3.29Å; R418-Q420 PolarHBondContact O-N 2.96Å; R418-D421 WeakPolarHBondContact O-CB 3.36Å; R418-D421 PolarHBondContact O-N 3.22Å; R418-D422 VanDerWaalsContact O-CG 3.3Å; R418-D422 PolarHBondContact O-N 2.66Å
419M98.4Very high97.4Very high0 Ų023.3 Ų23.30%013%0.132CC..Hα-helixtrans-63.3-37.2172.3-62.2172.675.600112.1P370 F397 R398 E414 G417 D421 D422 I423 Y448P370-M419 HydrophobicContact CB-CE 3.38Å; P370-M419 HydrophobicContact CG-CE 3.76Å; F397-M419 HydrophobicContact CD2-CB 4.47Å; F397-M419 HydrophobicContact CD2-CE 3.66Å; F397-M419 HydrophobicContact CE2-CE 3.46Å; F397-M419 VanDerWaalsContact CE2-CE 3.46Å; R398-M419 HydrophobicContact CG-CB 4.4Å; R398-M419 HydrophobicContact CG-CG 3.62Å; R398-M419 WeakPolarHBondContact O-CE 3.46Å; R398-M419 WeakPolarHBondContact O-CG 3.39Å; E414-M419 HydrophobicContact CB-CG 3.7Å; E414-M419 HydrophobicContact CB-SD 4.03Å; E414-M419 WeakPolarHBondContact O-CB 3.41Å; G417-M419 PolarHBondContact O-N 3.17Å; M419-D421 VanDerWaalsContact C-N 3.32Å; M419-D422 PolarHBondContact O-N 3.16Å; M419-I423 WeakPolarHBondContact O-CG1 3.49Å; M419-I423 PolarHBondContact O-N 3.11Å; M419-Y448 WeakPolarHBondContact CB-OH 3.17Å; M419-Y448 HydrophobicContact CE-CE1 3.97Å; M419-Y448 HydrophobicContact CE-CE2 3.84Å; M419-Y448 WeakPolarHBondContact CE-OH 3.36Å; M419-Y448 HydrophobicContact SD-CE2 4.37Å
420Q98.3Very high97.2Very high3 Ų322.3 Ų22.31%0.01413%0.125CC..Hα-helixtrans-71.4-32.9174.8-172.766.455.600111.5G417 R418 I423 N424 A452 Y455G417-Q420 WeakPolarHBondContact O-CB 3.21Å; G417-Q420 PolarHBondContact O-N 3.05Å; R418-Q420 VanDerWaalsContact C-N 3.29Å; R418-Q420 PolarHBondContact O-N 2.96Å; Q420-I423 PolarHBondContact O-N 2.86Å; Q420-N424 WeakPolarHBondContact O-CB 3.48Å; Q420-N424 VanDerWaalsContact O-CG 3.22Å; Q420-N424 PolarHBondContact O-N 2.83Å; Q420-N424 PolarHBondContact O-ND2 2.87Å; Q420-A452 PolarHBondContact OE1-O 2.91Å; Q420-Y455 HydrophobicContact CB-CD1 4.2Å; Q420-Y455 HydrophobicContact CB-CE1 4.25Å; Q420-Y455 HydrophobicContact CG-CD1 3.64Å; Q420-Y455 HydrophobicContact CG-CE1 3.93Å
421D98.3Very high97Very high48 Ų4822 Ų2226%0.25712%0.121SC..Hα-helixtrans-63-43.2173-77.4-30.7000111.6R336 G417 R418 M419 I423 N424 D425R336-D421 IonicContact CZ-OD1 3.66Å; R336-D421 IonicContact CZ-OD2 3.3Å; R336-D421 IonicContact NH1-OD1 3.72Å; R336-D421 PolarHBondContact NH1-OD1 2.77Å; R336-D421 IonicContact NH1-OD2 2.7Å; R336-D421 PolarHBondContact NH1-OD2 3.13Å; R336-D421 IonicContact NH2-OD1 3.33Å; R336-D421 PolarHBondContact NH2-OD1 2.98Å; G417-D421 PolarHBondContact O-N 3.22Å; R418-D421 WeakPolarHBondContact O-CB 3.36Å; R418-D421 PolarHBondContact O-N 3.22Å; M419-D421 VanDerWaalsContact C-N 3.32Å; D421-I423 VanDerWaalsContact C-N 3.34Å; D421-I423 PolarHBondContact O-N 2.75Å; D421-N424 CarbonylContact O-C 3.54Å; D421-N424 WeakPolarHBondContact O-CB 3.34Å; D421-N424 PolarHBondContact O-N 3.5Å; D421-N424 VanDerWaalsContact O-N 3.12Å; D421-D425 WeakPolarHBondContact O-CB 3.46Å; D421-D425 PolarHBondContact O-N 3.21Å
422D98.7Very high96.8Very high0 Ų028 Ų280%015%0.153CC..Hα-helixtrans-56.9-47.6174.7-64-6.9000111.7T335 Q341 F397 R398 R418 M419 N424 D425 A426T335-D422 HydrophobicContact CG2-CB 4.1Å; T335-D422 WeakPolarHBondContact CG2-OD1 3.2Å; Q341-D422 PolarHBondContact NE2-O 2.73Å; F397-D422 HydrophobicContact CB-CB 3.66Å; R398-D422 WeakPolarHBondContact CB-OD2 3.4Å; R398-D422 WeakPolarHBondContact CG-OD2 3.49Å; R398-D422 IonicContact CZ-OD1 3.22Å; R398-D422 VanDerWaalsContact CZ-OD1 3.27Å; R398-D422 IonicContact CZ-OD2 3.75Å; R398-D422 PolarHBondContact N-OD2 3.49Å; R398-D422 VanDerWaalsContact NE-CG 3.27Å; R398-D422 IonicContact NE-OD1 2.83Å; R398-D422 PolarHBondContact NE-OD1 3.13Å; R398-D422 VanDerWaalsContact NE-OD1 3.08Å; R398-D422 IonicContact NE-OD2 3.54Å; R398-D422 PolarHBondContact NE-OD2 3.27Å; R398-D422 IonicContact NH2-OD1 2.75Å; R398-D422 PolarHBondContact NH2-OD1 3.12Å; R398-D422 IonicContact NH2-OD2 2.66Å; R418-D422 VanDerWaalsContact O-CG 3.3Å; R418-D422 PolarHBondContact O-N 2.66Å; M419-D422 PolarHBondContact O-N 3.16Å; D422-N424 VanDerWaalsContact C-N 3.26Å; D422-N424 PolarHBondContact O-N 2.82Å; D422-D425 PolarHBondContact O-N 2.75Å; D422-A426 WeakPolarHBondContact O-CB 3.12Å; D422-A426 PolarHBondContact O-N 3.16Å
423I98.2Very high96.6Very high1 Ų130.2 Ų30.21%0.00517%0.166CC..Hα-helixtrans-58-42.2177.6-69.7168.8000111N364 I366 F397 M419 Q420 D421 F427 I443 A452N364-I423 WeakPolarHBondContact ND2-CG2 3.46Å; N364-I423 PolarHBondContact ND2-O 3.44Å; N364-I423 VanDerWaalsContact ND2-O 3.1Å; I366-I423 HydrophobicContact CD1-CB 4.41Å; I366-I423 HydrophobicContact CD1-CD1 4.23Å; I366-I423 HydrophobicContact CD1-CG1 4.11Å; I366-I423 HydrophobicContact CD1-CG2 3.5Å; I366-I423 VanDerWaalsContact CD1-CG2 3.5Å; I366-I423 HydrophobicContact CG1-CD1 4.39Å; I366-I423 HydrophobicContact CG1-CG2 4.28Å; I366-I423 HydrophobicContact CG2-CD1 3.71Å; I366-I423 HydrophobicContact CG2-CG1 4.45Å; F397-I423 HydrophobicContact CB-CG1 4.4Å; F397-I423 HydrophobicContact CD1-CD1 4.16Å; F397-I423 HydrophobicContact CD1-CG1 3.86Å; F397-I423 HydrophobicContact CE1-CD1 4.39Å; F397-I423 HydrophobicContact CG-CG1 4.22Å; M419-I423 WeakPolarHBondContact O-CG1 3.49Å; M419-I423 PolarHBondContact O-N 3.11Å; Q420-I423 PolarHBondContact O-N 2.86Å; D421-I423 VanDerWaalsContact C-N 3.34Å; D421-I423 PolarHBondContact O-N 2.75Å; I423-F427 PolarHBondContact O-N 3.29Å; I423-I443 HydrophobicContact CG2-CD1 4.18Å; I423-A452 HydrophobicContact CD1-CB 3.79Å
424N96.8Very high96.3Very high4 Ų435.4 Ų35.42%0.02118%0.18CC..Hα-helixtrans-73.1-34.6179-73.1-29.5000113Q420 D421 D422 F427 A428 K463 Y464Q420-N424 WeakPolarHBondContact O-CB 3.48Å; Q420-N424 VanDerWaalsContact O-CG 3.22Å; Q420-N424 PolarHBondContact O-N 2.83Å; Q420-N424 PolarHBondContact O-ND2 2.87Å; D421-N424 CarbonylContact O-C 3.54Å; D421-N424 WeakPolarHBondContact O-CB 3.34Å; D421-N424 PolarHBondContact O-N 3.5Å; D421-N424 VanDerWaalsContact O-N 3.12Å; D422-N424 VanDerWaalsContact C-N 3.26Å; D422-N424 PolarHBondContact O-N 2.82Å; N424-F427 PolarHBondContact O-N 2.85Å; N424-A428 WeakPolarHBondContact O-CB 3.14Å; N424-A428 PolarHBondContact O-N 2.78Å; N424-K463 HydrophobicContact CB-CD 4.38Å; N424-K463 VanDerWaalsContact CG-NZ 3.34Å; N424-K463 PolarHBondContact ND2-NZ 3.33Å; N424-K463 VanDerWaalsContact ND2-NZ 3.15Å; N424-Y464 PolarHBondContact OD1-OH 2.86Å
425D97.8Very high96Very high22 Ų2234.7 Ų34.712%0.11818%0.178CC..Hα-helixtrans-71.4-38.9179.7-69.1-9.9000110.5R336 D421 D422 F427 A428 W429R336-D425 WeakPolarHBondContact CB-OD2 3.46Å; R336-D425 WeakPolarHBondContact CG-OD2 3.28Å; R336-D425 IonicContact CZ-OD1 3.67Å; R336-D425 VanDerWaalsContact CZ-OD1 3.28Å; R336-D425 PolarHBondContact N-OD2 3.07Å; R336-D425 IonicContact NE-OD1 3.82Å; R336-D425 PolarHBondContact NE-OD1 2.81Å; R336-D425 IonicContact NE-OD2 3.54Å; R336-D425 PolarHBondContact NE-OD2 2.85Å; R336-D425 IonicContact NH2-OD1 3.43Å; R336-D425 PolarHBondContact NH2-OD1 2.66Å; R336-D425 IonicContact NH2-OD2 2.78Å; D421-D425 WeakPolarHBondContact O-CB 3.46Å; D421-D425 PolarHBondContact O-N 3.21Å; D422-D425 PolarHBondContact O-N 2.75Å; D425-F427 VanDerWaalsContact C-N 3.28Å; D425-F427 PolarHBondContact O-N 2.85Å; D425-A428 PolarHBondContact O-N 3.12Å; D425-W429 WeakPolarHBondContact O-CB 3.47Å; D425-W429 PolarHBondContact O-N 2.93Å
426A96.7Very high95.8Very high0 Ų034.1 Ų34.10%018%0.176CC..Hα-helixtrans-55.4-47170.400000111.8L393 C395 D422 W429 A430L393-A426 HydrophobicContact CD2-CB 4.06Å; C395-A426 HydrophobicContact CB-CB 4.21Å; C395-A426 WeakPolarHBondContact SG-CB 3.33Å; D422-A426 WeakPolarHBondContact O-CB 3.12Å; D422-A426 PolarHBondContact O-N 3.16Å; A426-W429 PolarHBondContact O-N 3.45Å; A426-A430 PolarHBondContact O-N 2.84Å; A426-A430 VanDerWaalsContact O-N 3.15Å
427F92.7Very high95.7Very high24 Ų2435.7 Ų35.711%0.10518%0.182CC..Hα-helixtrans-63.4-48.9177.1170-99.4000111.8I423 N424 D425 W429 A430 A431 V436 M441 Y464I423-F427 PolarHBondContact O-N 3.29Å; N424-F427 PolarHBondContact O-N 2.85Å; D425-F427 VanDerWaalsContact C-N 3.28Å; D425-F427 PolarHBondContact O-N 2.85Å; F427-W429 VanDerWaalsContact C-N 3.27Å; F427-W429 PolarHBondContact O-N 3.24Å; F427-A430 PolarHBondContact O-N 2.99Å; F427-A430 VanDerWaalsContact O-N 3.12Å; F427-A431 HydrophobicContact CE2-CB 4.41Å; F427-A431 HydrophobicContact CZ-CB 3.83Å; F427-A431 PolarHBondContact O-N 3.03Å; F427-A431 VanDerWaalsContact O-N 3.13Å; F427-V436 HydrophobicContact CE2-CG2 3.87Å; F427-M441 HydrophobicContact CD1-CE 3.87Å; F427-M441 HydrophobicContact CD2-CB 4.37Å; F427-M441 HydrophobicContact CD2-CE 4.11Å; F427-M441 HydrophobicContact CD2-CG 3.77Å; F427-M441 HydrophobicContact CD2-SD 4.18Å; F427-M441 HydrophobicContact CE1-CE 3.07Å; F427-M441 HydrophobicContact CE1-SD 3.86Å; F427-M441 HydrophobicContact CE2-CB 4.12Å; F427-M441 HydrophobicContact CE2-CE 3.43Å; F427-M441 VanDerWaalsContact CE2-CE 3.43Å; F427-M441 HydrophobicContact CE2-CG 3.13Å; F427-M441 HydrophobicContact CE2-SD 3.13Å; F427-M441 WeakPolarHBondContact CE2-SD 3.39Å; F427-M441 HydrophobicContact CG-CE 4.36Å; F427-M441 HydrophobicContact CZ-CE 2.88Å; F427-M441 HydrophobicContact CZ-CG 3.69Å; F427-M441 HydrophobicContact CZ-SD 2.96Å; F427-M441 WeakPolarHBondContact CZ-SD 3.36Å; F427-Y464 HydrophobicContact CG-CE1 4.42Å
428A95.4Very high95.5Very high38 Ų3837.7 Ų37.731%0.31419%0.192SC..Hα-helixtrans-59.9-37.7178.200000112.2N424 D425 A431 N432N424-A428 WeakPolarHBondContact O-CB 3.14Å; N424-A428 PolarHBondContact O-N 2.78Å; D425-A428 PolarHBondContact O-N 3.12Å; A428-A431 PolarHBondContact O-N 3.47Å; A428-N432 WeakPolarHBondContact O-CB 3.32Å; A428-N432 PolarHBondContact O-N 3.05Å; A428-N432 PolarHBondContact O-ND2 2.97Å
429W97Very high95.3Very high52 Ų5238 Ų3820%0.19720%0.202CC..Hα-helixtrans-60.7-45.3174.3176.594.9000111.9V331 V333 D425 A426 F427 A431 N432 N433 L435V331-W429 HydrophobicContact CB-CH2 3.92Å; V331-W429 HydrophobicContact CB-CZ2 4.36Å; V331-W429 HydrophobicContact CG1-CH2 4Å; V331-W429 HydrophobicContact CG2-CH2 3.7Å; V331-W429 HydrophobicContact CG2-CZ2 4.43Å; V331-W429 HydrophobicContact CG2-CZ3 3.85Å; V333-W429 HydrophobicContact CB-CD2 4.45Å; V333-W429 HydrophobicContact CB-CG 4.34Å; V333-W429 HydrophobicContact CG1-CB 3.5Å; V333-W429 VanDerWaalsContact CG1-CB 3.5Å; V333-W429 HydrophobicContact CG1-CD2 4.06Å; V333-W429 HydrophobicContact CG1-CG 3.5Å; V333-W429 HydrophobicContact CG2-CD2 3.66Å; V333-W429 HydrophobicContact CG2-CE3 3.75Å; V333-W429 HydrophobicContact CG2-CG 4.06Å; V333-W429 HydrophobicContact CG2-CZ2 4.47Å; V333-W429 HydrophobicContact CG2-CZ3 4.24Å; D425-W429 WeakPolarHBondContact O-CB 3.47Å; D425-W429 PolarHBondContact O-N 2.93Å; A426-W429 PolarHBondContact O-N 3.45Å; F427-W429 VanDerWaalsContact C-N 3.27Å; F427-W429 PolarHBondContact O-N 3.24Å; W429-A431 VanDerWaalsContact C-N 3.33Å; W429-A431 PolarHBondContact O-N 3.03Å; W429-N432 PolarHBondContact O-N 2.69Å; W429-N433 PolarHBondContact NE1-ND2 3.42Å; W429-N433 WeakPolarHBondContact O-CB 3.33Å; W429-N433 PolarHBondContact O-N 2.97Å; W429-N433 PolarHBondContact O-ND2 3.39Å; W429-L435 HydrophobicContact CE3-CD1 4.46Å; W429-L435 HydrophobicContact CH2-CD1 3.76Å; W429-L435 HydrophobicContact CZ3-CD1 3.58Å
430A94.6Very high95.2Very high1 Ų141.4 Ų41.41%0.00822%0.215CC..Hα-helixtrans-62.8-41.1179.100000111.7L393 A426 F427 R434 L435 V436L393-A430 HydrophobicContact CD2-CB 4.3Å; A426-A430 PolarHBondContact O-N 2.84Å; A426-A430 VanDerWaalsContact O-N 3.15Å; F427-A430 PolarHBondContact O-N 2.99Å; F427-A430 VanDerWaalsContact O-N 3.12Å; A430-R434 PolarHBondContact O-N 3.33Å; A430-L435 WeakPolarHBondContact O-CB 3.48Å; A430-L435 PolarHBondContact O-N 3.16Å; A430-V436 HydrophobicContact CB-CG2 3.91Å
431A93.7Very high95.1Very high17 Ų1741.4 Ų41.414%0.1422%0.215CC..Hα-helixtrans-64.6-46.8174.900000112.3F427 A428 W429 N433 R434 V436F427-A431 HydrophobicContact CE2-CB 4.41Å; F427-A431 HydrophobicContact CZ-CB 3.83Å; F427-A431 PolarHBondContact O-N 3.03Å; F427-A431 VanDerWaalsContact O-N 3.13Å; A428-A431 PolarHBondContact O-N 3.47Å; W429-A431 VanDerWaalsContact C-N 3.33Å; W429-A431 PolarHBondContact O-N 3.03Å; A431-N433 VanDerWaalsContact C-N 3.26Å; A431-N433 PolarHBondContact O-N 3.46Å; A431-R434 WeakPolarHBondContact O-CA 3.18Å; A431-R434 PolarHBondContact O-N 3.04Å; A431-V436 HydrophobicContact CB-CG2 4.28Å
432N94.7Very high95.1Very high131 Ų13139.1 Ų39.170%0.70120%0.203SC*.Hα-helixtrans-63.5-31.4179.9-72.2-20.6000112.8A428 W429 R434A428-N432 WeakPolarHBondContact O-CB 3.32Å; A428-N432 PolarHBondContact O-N 3.05Å; A428-N432 PolarHBondContact O-ND2 2.97Å; W429-N432 PolarHBondContact O-N 2.69Å; N432-R434 PolarHBondContact O-N 2.97Å
433N93Very high95.1Very high83 Ų8339.1 Ų39.144%0.44420%0.203SC..THydrogen-bonded Turntrans-84.18.9174.1-74.6-85.6000113.3W429 A431 L435W429-N433 PolarHBondContact NE1-ND2 3.42Å; W429-N433 WeakPolarHBondContact O-CB 3.33Å; W429-N433 PolarHBondContact O-N 2.97Å; W429-N433 PolarHBondContact O-ND2 3.39Å; A431-N433 VanDerWaalsContact C-N 3.26Å; A431-N433 PolarHBondContact O-N 3.46Å; N433-L435 HydrophobicContact CB-CD1 3.86Å; N433-L435 HydrophobicContact CB-CG 3.98Å; N433-L435 PolarHBondContact O-N 2.8Å
434R91.9Very high95.1Very high127 Ų12739.2 Ų39.248%0.47920%0.203SC..THydrogen-bonded Turntrans54.938.7179.4-50.9-172.468.7178-2.6112.5D356 L359 A430 A431 N432D356-R434 VanDerWaalsContact CB-NH2 3.28Å; D356-R434 IonicContact OD1-CZ 2.94Å; D356-R434 IonicContact OD1-NE 3.64Å; D356-R434 PolarHBondContact OD1-NE 2.65Å; D356-R434 IonicContact OD1-NH1 2.69Å; D356-R434 IonicContact OD1-NH2 3.2Å; D356-R434 PolarHBondContact OD1-NH2 2.83Å; D356-R434 IonicContact OD2-CZ 2.79Å; D356-R434 IonicContact OD2-NE 3.86Å; D356-R434 IonicContact OD2-NH1 3.48Å; D356-R434 PolarHBondContact OD2-NH1 2.69Å; D356-R434 IonicContact OD2-NH2 3.34Å; D356-R434 PolarHBondContact OD2-NH2 2.82Å; L359-R434 HydrophobicContact CD1-CB 4.13Å; L359-R434 HydrophobicContact CD2-CB 4.25Å; L359-R434 WeakPolarHBondContact CD2-O 3.49Å; A430-R434 PolarHBondContact O-N 3.33Å; A431-R434 WeakPolarHBondContact O-CA 3.18Å; A431-R434 PolarHBondContact O-N 3.04Å; N432-R434 PolarHBondContact O-N 2.97Å
435L91.7Very high95.2Very high23 Ų2339.3 Ų39.312%0.1221%0.205CC..SBendtrans-93-23.9176.3-60.9168.2000111.5L345 P360 W429 A430 N433L345-L435 HydrophobicContact CD2-CB 4.24Å; L345-L435 HydrophobicContact CD2-CD1 3.79Å; L345-L435 HydrophobicContact CD2-CD2 4.37Å; L345-L435 HydrophobicContact CD2-CG 4.35Å; P360-L435 WeakPolarHBondContact CG-O 3.5Å; W429-L435 HydrophobicContact CE3-CD1 4.46Å; W429-L435 HydrophobicContact CH2-CD1 3.76Å; W429-L435 HydrophobicContact CZ3-CD1 3.58Å; A430-L435 WeakPolarHBondContact O-CB 3.48Å; A430-L435 PolarHBondContact O-N 3.16Å; N433-L435 HydrophobicContact CB-CD1 3.86Å; N433-L435 HydrophobicContact CB-CG 3.98Å; N433-L435 PolarHBondContact O-N 2.8Å
436V93.2Very high95.2Very high5 Ų539.6 Ų39.63%0.0321%0.211CC..SBendtrans-141.8152.5179.8-61.60000110.9L359 P360 V391 F427 A430 A431 S438L359-V436 WeakPolarHBondContact CD1-O 3.38Å; P360-V436 CarbonylContact O-C 3.48Å; P360-V436 WeakPolarHBondContact O-CA 3.39Å; V391-V436 HydrophobicContact CB-CG1 3.55Å; V391-V436 HydrophobicContact CG1-CG1 3.58Å; V391-V436 HydrophobicContact CG2-CG1 4.1Å; F427-V436 HydrophobicContact CE2-CG2 3.87Å; A430-V436 HydrophobicContact CB-CG2 3.91Å; A431-V436 HydrophobicContact CB-CG2 4.28Å; V436-S438 PolarHBondContact O-N 3.21Å
437D92.6Very high95.2Very high40 Ų4040.8 Ų40.821%0.21422%0.219CC..  trans-71.4115.3170.5179.7-13.4000109.8L359 P360 N439 R440L359-D437 HydrophobicContact CB-CB 4.04Å; P360-D437 PolarHBondContact O-N 3.47Å; D437-N439 PolarHBondContact O-N 2.79Å; D437-N439 PolarHBondContact OD1-N 2.84Å; D437-R440 HydrophobicContact CB-CB 4.18Å; D437-R440 HydrophobicContact CB-CG 4.48Å; D437-R440 PolarHBondContact O-N 2.66Å; D437-R440 WeakPolarHBondContact OD2-CG 3.4Å; D437-R440 IonicContact OD2-CZ 3.69Å; D437-R440 IonicContact OD2-NE 2.66Å; D437-R440 PolarHBondContact OD2-NE 2.76Å; D437-R440 IonicContact OD2-NH2 3.76Å
438S93.4Very high95.5Very high68 Ų6839.6 Ų39.648%0.47621%0.214SC..THydrogen-bonded Turntrans-61.4-14.7-176.966.10000114.7V436 M441V436-S438 PolarHBondContact O-N 3.21Å; S438-M441 VanDerWaalsContact CA-SD 3.57Å; S438-M441 VanDerWaalsContact O-CE 3.3Å; S438-M441 WeakPolarHBondContact O-CE 3.34Å
439N94.2Very high95.6Very high112 Ų11237.8 Ų37.860%0.59920%0.199SC*.THydrogen-bonded Turntrans-98-9.4177-63.6-56.6000113D437 Q465D437-N439 PolarHBondContact O-N 2.79Å; D437-N439 PolarHBondContact OD1-N 2.84Å; N439-Q465 WeakPolarHBondContact O-CG 3.21Å; N439-Q465 PolarHBondContact O-NE2 3.27Å
440R95.3Very high95.7Very high70 Ų7035.3 Ų35.326%0.26419%0.189SC..SBendtrans-123.772.9-175.5-61.2-167.9-64.6150.3-3.7110.8L359 A361 G362 D437 L590L359-R440 PolarHBondContact O-NH2 2.82Å; A361-R440 CarbonylContact C-O 3.55Å; A361-R440 WeakPolarHBondContact CA-O 3.44Å; A361-R440 HydrophobicContact CB-CB 3.71Å; A361-R440 VanDerWaalsContact CB-O 3.25Å; A361-R440 WeakPolarHBondContact CB-O 3.39Å; G362-R440 PolarHBondContact N-O 2.66Å; D437-R440 HydrophobicContact CB-CB 4.18Å; D437-R440 HydrophobicContact CB-CG 4.48Å; D437-R440 PolarHBondContact O-N 2.66Å; D437-R440 WeakPolarHBondContact OD2-CG 3.4Å; D437-R440 IonicContact OD2-CZ 3.69Å; D437-R440 IonicContact OD2-NE 2.66Å; D437-R440 PolarHBondContact OD2-NE 2.76Å; D437-R440 IonicContact OD2-NH2 3.76Å; R440-L590 HydrophobicContact CB-CD2 4.16Å; R440-L590 PolarHBondContact NH1-O 3.38Å
441M96.5Very high95.9Very high4 Ų435.3 Ų35.32%0.0219%0.189CC..EExtended strand (participates in β ladder)trans-128.8150.4168.1-50.690.539.600115.3G362 F427 S438 K463 Y464 Q465G362-M441 CarbonylContact O-C 3.3Å; G362-M441 WeakPolarHBondContact O-CA 3.17Å; G362-M441 WeakPolarHBondContact O-CB 3.5Å; F427-M441 HydrophobicContact CD1-CE 3.87Å; F427-M441 HydrophobicContact CD2-CB 4.37Å; F427-M441 HydrophobicContact CD2-CE 4.11Å; F427-M441 HydrophobicContact CD2-CG 3.77Å; F427-M441 HydrophobicContact CD2-SD 4.18Å; F427-M441 HydrophobicContact CE1-CE 3.07Å; F427-M441 HydrophobicContact CE1-SD 3.86Å; F427-M441 HydrophobicContact CE2-CB 4.12Å; F427-M441 HydrophobicContact CE2-CE 3.43Å; F427-M441 VanDerWaalsContact CE2-CE 3.43Å; F427-M441 HydrophobicContact CE2-CG 3.13Å; F427-M441 HydrophobicContact CE2-SD 3.13Å; F427-M441 WeakPolarHBondContact CE2-SD 3.39Å; F427-M441 HydrophobicContact CG-CE 4.36Å; F427-M441 HydrophobicContact CZ-CE 2.88Å; F427-M441 HydrophobicContact CZ-CG 3.69Å; F427-M441 HydrophobicContact CZ-SD 2.96Å; F427-M441 WeakPolarHBondContact CZ-SD 3.36Å; S438-M441 VanDerWaalsContact CA-SD 3.57Å; S438-M441 VanDerWaalsContact O-CE 3.3Å; S438-M441 WeakPolarHBondContact O-CE 3.34Å; M441-K463 WeakPolarHBondContact CE-O 3.29Å; M441-Y464 HydrophobicContact CB-CD1 4.22Å; M441-Y464 CarbonylContact O-C 3.59Å; M441-Q465 PolarHBondContact O-N 2.99Å
442A98.4Very high96.1Very high0 Ų034.5 Ų34.50%018%0.182CC..EExtended strand (participates in β ladder)trans-116.1166.4165.100000111.2G362 I363 N364 C466 F586 L590G362-A442 PolarHBondContact O-N 3.4Å; I363-A442 HydrophobicContact CD1-CB 3.77Å; N364-A442 PolarHBondContact N-O 2.99Å; A442-C466 WeakPolarHBondContact CA-O 3.46Å; A442-C466 WeakPolarHBondContact CB-O 3.47Å; A442-C466 VanDerWaalsContact CB-SG 3.59Å; A442-F586 HydrophobicContact CB-CD1 3.96Å; A442-F586 HydrophobicContact CB-CE1 3.48Å; A442-F586 VanDerWaalsContact CB-CE1 3.48Å; A442-F586 HydrophobicContact CB-CZ 4.07Å; A442-L590 HydrophobicContact CB-CD1 3.93Å
443I98.7Very high96.3Very high0 Ų028.2 Ų28.20%015%0.149CC..EExtended strand (participates in β ladder)trans-123.6138.7170.5-176.4168.8000108.7N364 I366 I423 T453 A456 L457 Y464 C466 G467 V468N364-I443 WeakPolarHBondContact O-CA 3.43Å; I366-I443 HydrophobicContact CD1-CD1 4.43Å; I366-I443 HydrophobicContact CD1-CG1 4.46Å; I366-I443 HydrophobicContact CG1-CD1 4Å; I366-I443 HydrophobicContact CG1-CG1 3.93Å; I423-I443 HydrophobicContact CG2-CD1 4.18Å; I443-T453 HydrophobicContact CG2-CG2 3.91Å; I443-A456 HydrophobicContact CD1-CB 3.8Å; I443-A456 HydrophobicContact CG2-CB 4.4Å; I443-L457 HydrophobicContact CG2-CD2 4.48Å; I443-Y464 HydrophobicContact CB-CD1 3.74Å; I443-Y464 HydrophobicContact CB-CD2 4.2Å; I443-Y464 HydrophobicContact CB-CE1 3.75Å; I443-Y464 HydrophobicContact CB-CE2 4.23Å; I443-Y464 HydrophobicContact CB-CG 3.96Å; I443-Y464 HydrophobicContact CD1-CE2 4.05Å; I443-Y464 HydrophobicContact CG2-CD1 4.03Å; I443-Y464 HydrophobicContact CG2-CD2 3.85Å; I443-Y464 HydrophobicContact CG2-CE1 4.43Å; I443-Y464 HydrophobicContact CG2-CE2 4.28Å; I443-Y464 HydrophobicContact CG2-CG 3.72Å; I443-C466 PolarHBondContact N-O 3.15Å; I443-G467 CarbonylContact O-C 3.6Å; I443-G467 WeakPolarHBondContact O-CA 3.49Å; I443-V468 PolarHBondContact O-N 2.95Å
444M98.7Very high96.6Very high2 Ų224.4 Ų24.41%0.0113%0.128CC..EExtended strand (participates in β ladder)trans-143.3155.2173.364-179.8-75.700112.5I363 N364 V365 I366 E381 L385 T453 V468 I582 F586I363-M444 HydrophobicContact CG2-CG 3.7Å; I363-M444 HydrophobicContact CG2-SD 3.73Å; N364-M444 PolarHBondContact O-N 3.4Å; V365-M444 WeakPolarHBondContact CA-O 3.23Å; V365-M444 HydrophobicContact CB-CG 4.33Å; V365-M444 HydrophobicContact CG2-CG 3.69Å; V365-M444 HydrophobicContact CG2-SD 3.98Å; I366-M444 PolarHBondContact N-O 3.03Å; E381-M444 HydrophobicContact CG-CE 4.3Å; E381-M444 WeakPolarHBondContact OE2-CE 3.48Å; L385-M444 HydrophobicContact CD1-SD 3.73Å; M444-T453 WeakPolarHBondContact CA-OG1 3.48Å; M444-V468 VanDerWaalsContact CA-O 3.25Å; M444-V468 WeakPolarHBondContact CA-O 3.43Å; M444-V468 HydrophobicContact CB-CB 3.68Å; M444-V468 HydrophobicContact CB-CG2 4.32Å; M444-I582 HydrophobicContact CE-CD1 4.25Å; M444-F586 HydrophobicContact CB-CZ 4.32Å; M444-F586 HydrophobicContact CG-CZ 4.47Å; M444-F586 HydrophobicContact SD-CE2 3.8Å; M444-F586 HydrophobicContact SD-CZ 3.89Å
445G98.3Very high96.9Very high7 Ų719.8 Ų19.87%0.07211%0.111CC..EExtended strand (participates in β ladder)trans176.817116800000113.2G450 T453 V468 E470G445-G450 VanDerWaalsContact C-N 3.3Å; G445-G450 WeakPolarHBondContact O-CA 3.33Å; G445-G450 PolarHBondContact O-N 2.89Å; G445-T453 PolarHBondContact N-OG1 3.05Å; G445-V468 PolarHBondContact N-O 3.46Å; G445-E470 PolarHBondContact O-N 2.89Å
446A97.5Very high97.2Very high28 Ų2818.7 Ų18.723%0.23111%0.105CC..EExtended strand (participates in β ladder)trans-112.5152.117800000111.5G368 Y448 G449 G450 E470G368-A446 WeakPolarHBondContact CA-O 3.5Å; A446-Y448 PolarHBondContact O-N 3.43Å; A446-G449 WeakPolarHBondContact O-CA 3.42Å; A446-G449 PolarHBondContact O-N 3.42Å; A446-G450 PolarHBondContact O-N 2.74Å; A446-E470 CarbonylContact C-O 3.54Å; A446-E470 VanDerWaalsContact CA-O 3.27Å; A446-E470 WeakPolarHBondContact CA-O 3.49Å; A446-E470 HydrophobicContact CB-CB 3.85Å; A446-E470 HydrophobicContact CB-CG 4.05Å; A446-E470 WeakPolarHBondContact CB-OE2 3.23Å
447S97.5Very high97.4Very high24 Ų2418.5 Ų18.517%0.16810%0.104CC..THydrogen-bonded Turntrans58.7-122.6176.7-167.30000110.7G449 G450 F451 E470 C471 P473 H567S447-G449 PolarHBondContact O-N 2.98Å; S447-G450 CarbonylContact O-C 3.53Å; S447-G450 WeakPolarHBondContact O-CA 3.3Å; S447-G450 PolarHBondContact O-N 3.35Å; S447-F451 PolarHBondContact O-N 3.15Å; S447-E470 PolarHBondContact N-O 3.24Å; S447-C471 WeakPolarHBondContact CA-O 3.25Å; S447-P473 WeakPolarHBondContact O-CD 3.38Å; S447-H567 VanDerWaalsContact CB-NE2 3.27Å; S447-H567 WeakPolarHBondContact CB-NE2 3.22Å; S447-H567 PolarHBondContact OG-CE1 2.7Å; S447-H567 PolarHBondContact OG-NE2 3Å
448Y98.4Very high97.7Very high0 Ų016.6 Ų16.60%09%0.094CC..Hα-helixtrans-52.7-39169.8175.1-94.2000113.3I366 P370 F397 W415 M419 A446 G450 F451 A452I366-Y448 HydrophobicContact CG2-CE1 4.39Å; P370-Y448 HydrophobicContact CB-CD1 3.73Å; P370-Y448 HydrophobicContact CB-CD2 3.86Å; P370-Y448 HydrophobicContact CB-CE1 4Å; P370-Y448 HydrophobicContact CB-CE2 4.08Å; P370-Y448 HydrophobicContact CB-CG 3.67Å; P370-Y448 HydrophobicContact CG-CD2 4.05Å; P370-Y448 HydrophobicContact CG-CE2 4.3Å; P370-Y448 HydrophobicContact CG-CG 4.27Å; F397-Y448 HydrophobicContact CD2-CE1 4.31Å; F397-Y448 HydrophobicContact CE1-CE1 4.16Å; F397-Y448 HydrophobicContact CE2-CD1 4.02Å; F397-Y448 AromaticContact CE2-CE1 3.39Å; F397-Y448 HydrophobicContact CE2-CE1 3.39Å; F397-Y448 AromaticContact CZ-CD1 3.64Å; F397-Y448 HydrophobicContact CZ-CD1 3.64Å; F397-Y448 AromaticContact CZ-CE1 3.29Å; F397-Y448 HydrophobicContact CZ-CE1 3.29Å; W415-Y448 AromaticContact CD1-CE2 3.99Å; W415-Y448 AromaticContact CD2-CD2 3.64Å; W415-Y448 HydrophobicContact CD2-CD2 3.64Å; W415-Y448 AromaticContact CD2-CE2 3.61Å; W415-Y448 HydrophobicContact CD2-CE2 3.61Å; W415-Y448 AromaticContact CE2-CD2 3.49Å; W415-Y448 VanDerWaalsContact CE2-CD2 3.49Å; W415-Y448 AromaticContact CE2-CE2 3.74Å; W415-Y448 AromaticContact CE3-CD2 3.8Å; W415-Y448 HydrophobicContact CE3-CD2 3.8Å; W415-Y448 HydrophobicContact CE3-CE2 4.03Å; W415-Y448 HydrophobicContact CG-CD2 4.35Å; W415-Y448 AromaticContact CG-CE2 3.84Å; W415-Y448 HydrophobicContact CG-CE2 3.84Å; W415-Y448 AromaticContact CH2-CD2 3.77Å; W415-Y448 HydrophobicContact CH2-CD2 3.77Å; W415-Y448 AromaticContact CZ2-CD2 3.6Å; W415-Y448 HydrophobicContact CZ2-CD2 3.6Å; W415-Y448 HydrophobicContact CZ2-CE2 4.33Å; W415-Y448 AromaticContact CZ3-CD2 3.85Å; W415-Y448 HydrophobicContact CZ3-CD2 3.85Å; W415-Y448 AromaticContact NE1-CE2 3.93Å; M419-Y448 WeakPolarHBondContact CB-OH 3.17Å; M419-Y448 HydrophobicContact CE-CE1 3.97Å; M419-Y448 HydrophobicContact CE-CE2 3.84Å; M419-Y448 WeakPolarHBondContact CE-OH 3.36Å; M419-Y448 HydrophobicContact SD-CE2 4.37Å; A446-Y448 PolarHBondContact O-N 3.43Å; Y448-G450 PolarHBondContact O-N 2.88Å; Y448-F451 HydrophobicContact CD2-CD1 4.19Å; Y448-F451 AromaticContact CE2-CD1 3.95Å; Y448-F451 HydrophobicContact CE2-CD1 3.95Å; Y448-F451 HydrophobicContact CE2-CE1 4.32Å; Y448-F451 WeakPolarHBondContact O-CA 3.12Å; Y448-F451 WeakPolarHBondContact O-CB 3.49Å; Y448-F451 PolarHBondContact O-N 2.83Å; Y448-F451 VanDerWaalsContact O-N 3.15Å; Y448-A452 HydrophobicContact CE1-CB 4.39Å; Y448-A452 PolarHBondContact O-N 3.42Å
449G98.4Very high97.9Very high0 Ų016.2 Ų16.20%08%0.083CC..Hα-helixtrans-65-30.8175.300000112.7I366 A446 S447 A452 T453I366-G449 WeakPolarHBondContact O-CA 3.4Å; A446-G449 WeakPolarHBondContact O-CA 3.42Å; A446-G449 PolarHBondContact O-N 3.42Å; S447-G449 PolarHBondContact O-N 2.98Å; G449-A452 PolarHBondContact O-N 3.25Å; G449-T453 WeakPolarHBondContact O-CB 3.49Å; G449-T453 PolarHBondContact O-N 2.83Å; G449-T453 PolarHBondContact O-OG1 3.41Å
450G98.4Very high97.9Very high0 Ų012.6 Ų12.60%06%0.064CC..Hα-helixtrans-67.9-44.7169.900000111.7G445 A446 S447 Y448 A452 T453 L454 A472G445-G450 VanDerWaalsContact C-N 3.3Å; G445-G450 WeakPolarHBondContact O-CA 3.33Å; G445-G450 PolarHBondContact O-N 2.89Å; A446-G450 PolarHBondContact O-N 2.74Å; S447-G450 CarbonylContact O-C 3.53Å; S447-G450 WeakPolarHBondContact O-CA 3.3Å; S447-G450 PolarHBondContact O-N 3.35Å; Y448-G450 PolarHBondContact O-N 2.88Å; G450-A452 VanDerWaalsContact C-N 3.34Å; G450-A452 PolarHBondContact O-N 3.44Å; G450-T453 WeakPolarHBondContact O-CB 3.47Å; G450-T453 PolarHBondContact O-N 2.62Å; G450-L454 WeakPolarHBondContact O-CG 3.49Å; G450-L454 PolarHBondContact O-N 2.95Å; G450-A472 VanDerWaalsContact C-CB 3.43Å
451F98.7Very high97.9Very high0 Ų010.6 Ų10.60%06%0.061CC..Hα-helixtrans-55.2-48.6170.4162.9-85000111W415 S447 Y448 T453 L454 Y455 P473 L476 P516W415-F451 HydrophobicContact CB-CE1 3.94Å; W415-F451 HydrophobicContact CB-CZ 3.86Å; W415-F451 HydrophobicContact CD2-CD1 4.49Å; W415-F451 HydrophobicContact CD2-CE1 4.45Å; W415-F451 HydrophobicContact CE3-CB 4.43Å; W415-F451 AromaticContact CE3-CD1 3.77Å; W415-F451 HydrophobicContact CE3-CD1 3.77Å; W415-F451 AromaticContact CE3-CD2 3.84Å; W415-F451 HydrophobicContact CE3-CD2 3.84Å; W415-F451 AromaticContact CE3-CE1 3.97Å; W415-F451 HydrophobicContact CE3-CE1 3.97Å; W415-F451 AromaticContact CE3-CE2 4Å; W415-F451 HydrophobicContact CE3-CE2 4Å; W415-F451 AromaticContact CE3-CG 3.74Å; W415-F451 HydrophobicContact CE3-CG 3.74Å; W415-F451 HydrophobicContact CE3-CZ 4.09Å; W415-F451 HydrophobicContact CG-CE1 4.47Å; W415-F451 HydrophobicContact CZ3-CB 4.19Å; W415-F451 HydrophobicContact CZ3-CD1 4.35Å; W415-F451 HydrophobicContact CZ3-CD2 4.19Å; W415-F451 AromaticContact CZ3-CG 3.99Å; W415-F451 HydrophobicContact CZ3-CG 3.99Å; S447-F451 PolarHBondContact O-N 3.15Å; Y448-F451 HydrophobicContact CD2-CD1 4.19Å; Y448-F451 AromaticContact CE2-CD1 3.95Å; Y448-F451 HydrophobicContact CE2-CD1 3.95Å; Y448-F451 HydrophobicContact CE2-CE1 4.32Å; Y448-F451 WeakPolarHBondContact O-CA 3.12Å; Y448-F451 WeakPolarHBondContact O-CB 3.49Å; Y448-F451 PolarHBondContact O-N 2.83Å; Y448-F451 VanDerWaalsContact O-N 3.15Å; F451-T453 VanDerWaalsContact C-N 3.29Å; F451-T453 PolarHBondContact O-N 2.86Å; F451-L454 PolarHBondContact O-N 2.86Å; F451-Y455 HydrophobicContact CE1-CD2 4.43Å; F451-Y455 HydrophobicContact CE1-CG 4.49Å; F451-Y455 HydrophobicContact CE2-CD2 4.49Å; F451-Y455 AromaticContact CZ-CD2 3.9Å; F451-Y455 HydrophobicContact CZ-CD2 3.9Å; F451-Y455 HydrophobicContact CZ-CG 4.38Å; F451-Y455 VanDerWaalsContact O-CB 3.26Å; F451-Y455 WeakPolarHBondContact O-CB 2.91Å; F451-Y455 PolarHBondContact O-N 3.1Å; F451-P473 HydrophobicContact CB-CB 4.35Å; F451-P473 HydrophobicContact CB-CG 4.4Å; F451-P473 VanDerWaalsContact CD2-O 3.27Å; F451-P473 WeakPolarHBondContact CD2-O 3.27Å; F451-L476 HydrophobicContact CD2-CD2 3.73Å; F451-L476 HydrophobicContact CD2-CG 4.49Å; F451-L476 HydrophobicContact CE2-CD1 3.94Å; F451-L476 HydrophobicContact CE2-CD2 3.75Å; F451-L476 HydrophobicContact CE2-CG 4.03Å; F451-L476 HydrophobicContact CZ-CD1 4.45Å; F451-P516 HydrophobicContact CD2-CG 3.84Å; F451-P516 VanDerWaalsContact CE2-CD 3.47Å; F451-P516 HydrophobicContact CE2-CG 3.91Å
452A98.6Very high97.8Very high0 Ų017 Ų170%010%0.095CC..Hα-helixtrans-63.2-36.6-179.800000111.8I366 Q420 I423 Y448 G449 G450 A456I366-A452 HydrophobicContact CG2-CB 4.01Å; Q420-A452 PolarHBondContact OE1-O 2.91Å; I423-A452 HydrophobicContact CD1-CB 3.79Å; Y448-A452 HydrophobicContact CE1-CB 4.39Å; Y448-A452 PolarHBondContact O-N 3.42Å; G449-A452 PolarHBondContact O-N 3.25Å; G450-A452 VanDerWaalsContact C-N 3.34Å; G450-A452 PolarHBondContact O-N 3.44Å; A452-A456 VanDerWaalsContact O-CB 3.23Å; A452-A456 WeakPolarHBondContact O-CB 3.1Å; A452-A456 PolarHBondContact O-N 2.79Å
453T98.7Very high97.6Very high0 Ų020.6 Ų20.60%011%0.111CC..Hα-helixtrans-62.6-51.9173.1-61.50000111.3I443 M444 G445 G449 G450 F451 Y455 A456 L457 V468 A469I443-T453 HydrophobicContact CG2-CG2 3.91Å; M444-T453 WeakPolarHBondContact CA-OG1 3.48Å; G445-T453 PolarHBondContact N-OG1 3.05Å; G449-T453 WeakPolarHBondContact O-CB 3.49Å; G449-T453 PolarHBondContact O-N 2.83Å; G449-T453 PolarHBondContact O-OG1 3.41Å; G450-T453 WeakPolarHBondContact O-CB 3.47Å; G450-T453 PolarHBondContact O-N 2.62Å; F451-T453 VanDerWaalsContact C-N 3.29Å; F451-T453 PolarHBondContact O-N 2.86Å; T453-Y455 VanDerWaalsContact C-N 3.33Å; T453-Y455 PolarHBondContact O-N 3.36Å; T453-A456 PolarHBondContact O-N 2.97Å; T453-L457 WeakPolarHBondContact O-CG 3.14Å; T453-L457 PolarHBondContact O-N 3.19Å; T453-L457 VanDerWaalsContact O-N 3.14Å; T453-V468 WeakPolarHBondContact CG2-O 3.3Å; T453-V468 PolarHBondContact OG1-O 3.25Å; T453-A469 HydrophobicContact CG2-CB 4.15Å
454L98.7Very high97.5Very high2 Ų220.6 Ų20.61%0.0111%0.111CC..Hα-helixtrans-62.5-41.4177.8-64.8-176.1000111.7G450 F451 L457 A458 A469 A472 P516 L527 M546G450-L454 WeakPolarHBondContact O-CG 3.49Å; G450-L454 PolarHBondContact O-N 2.95Å; F451-L454 PolarHBondContact O-N 2.86Å; L454-L457 PolarHBondContact O-N 2.93Å; L454-A458 VanDerWaalsContact O-CB 3.24Å; L454-A458 WeakPolarHBondContact O-CB 3.32Å; L454-A458 PolarHBondContact O-N 2.96Å; L454-A469 HydrophobicContact CD1-CB 4.49Å; L454-A469 HydrophobicContact CD2-CB 3.58Å; L454-A469 HydrophobicContact CG-CB 3.76Å; L454-A472 HydrophobicContact CD1-CB 3.61Å; L454-A472 HydrophobicContact CG-CB 4.12Å; L454-P516 HydrophobicContact CB-CB 3.6Å; L454-P516 HydrophobicContact CB-CG 3.88Å; L454-L527 HydrophobicContact CD2-CD1 4.24Å; L454-L527 HydrophobicContact CD2-CD2 3.78Å; L454-M546 HydrophobicContact CD1-CG 4.25Å; L454-M546 HydrophobicContact CD2-CE 4.26Å
455Y98.6Very high97.5Very high30 Ų3023 Ų2312%0.11812%0.122CC..Hα-helixtrans-62.6-47.3178.5-169.1-84.5000111.1G416 Q420 F451 T453 L457 A458 Y459 V514 P516G416-Y455 VanDerWaalsContact CA-CE2 3.47Å; G416-Y455 WeakPolarHBondContact O-CE1 3.47Å; G416-Y455 PolarHBondContact O-OH 3.34Å; Q420-Y455 HydrophobicContact CB-CD1 4.2Å; Q420-Y455 HydrophobicContact CB-CE1 4.25Å; Q420-Y455 HydrophobicContact CG-CD1 3.64Å; Q420-Y455 HydrophobicContact CG-CE1 3.93Å; F451-Y455 HydrophobicContact CE1-CD2 4.43Å; F451-Y455 HydrophobicContact CE1-CG 4.49Å; F451-Y455 HydrophobicContact CE2-CD2 4.49Å; F451-Y455 AromaticContact CZ-CD2 3.9Å; F451-Y455 HydrophobicContact CZ-CD2 3.9Å; F451-Y455 HydrophobicContact CZ-CG 4.38Å; F451-Y455 VanDerWaalsContact O-CB 3.26Å; F451-Y455 WeakPolarHBondContact O-CB 2.91Å; F451-Y455 PolarHBondContact O-N 3.1Å; T453-Y455 VanDerWaalsContact C-N 3.33Å; T453-Y455 PolarHBondContact O-N 3.36Å; Y455-L457 VanDerWaalsContact C-N 3.32Å; Y455-L457 PolarHBondContact O-N 3.33Å; Y455-A458 PolarHBondContact O-N 3.36Å; Y455-Y459 HydrophobicContact CD1-CD2 4.27Å; Y455-Y459 HydrophobicContact CD1-CG 4.44Å; Y455-Y459 AromaticContact CD2-CD2 3.61Å; Y455-Y459 HydrophobicContact CD2-CD2 3.61Å; Y455-Y459 AromaticContact CD2-CE2 3.87Å; Y455-Y459 HydrophobicContact CD2-CE2 3.87Å; Y455-Y459 HydrophobicContact CD2-CG 4.35Å; Y455-Y459 HydrophobicContact CE1-CD2 4.17Å; Y455-Y459 AromaticContact CE1-CG 3.98Å; Y455-Y459 HydrophobicContact CE1-CG 3.98Å; Y455-Y459 HydrophobicContact CE2-CD1 4.33Å; Y455-Y459 AromaticContact CE2-CD2 3.43Å; Y455-Y459 HydrophobicContact CE2-CD2 3.43Å; Y455-Y459 VanDerWaalsContact CE2-CD2 3.43Å; Y455-Y459 HydrophobicContact CE2-CE1 4.47Å; Y455-Y459 AromaticContact CE2-CE2 3.6Å; Y455-Y459 HydrophobicContact CE2-CE2 3.6Å; Y455-Y459 AromaticContact CE2-CG 3.84Å; Y455-Y459 HydrophobicContact CE2-CG 3.84Å; Y455-Y459 HydrophobicContact CG-CD2 4.03Å; Y455-Y459 AromaticContact CZ-CD2 3.73Å; Y455-Y459 AromaticContact CZ-CG 3.63Å; Y455-Y459 WeakPolarHBondContact O-CB 3.43Å; Y455-Y459 PolarHBondContact O-N 2.72Å; Y455-V514 WeakPolarHBondContact CD2-O 3.35Å; Y455-V514 WeakPolarHBondContact CE2-O 3.2Å; Y455-P516 HydrophobicContact CD2-CG 4.4Å
456A98.2Very high97.5Very high0 Ų022.7 Ų22.70%012%0.119CC..Hα-helixtrans-57.7-43.8177.700000112.1I443 A452 T453 T460 Y464I443-A456 HydrophobicContact CD1-CB 3.8Å; I443-A456 HydrophobicContact CG2-CB 4.4Å; A452-A456 VanDerWaalsContact O-CB 3.23Å; A452-A456 WeakPolarHBondContact O-CB 3.1Å; A452-A456 PolarHBondContact O-N 2.79Å; T453-A456 PolarHBondContact O-N 2.97Å; A456-T460 WeakPolarHBondContact CA-OG1 3.39Å; A456-T460 CarbonylContact O-C 3.58Å; A456-T460 VanDerWaalsContact O-CA 3.25Å; A456-T460 WeakPolarHBondContact O-CA 3.26Å; A456-T460 PolarHBondContact O-N 2.86Å; A456-T460 VanDerWaalsContact O-O 3.07Å; A456-T460 PolarHBondContact O-OG1 2.83Å; A456-Y464 HydrophobicContact CB-CD2 3.91Å; A456-Y464 HydrophobicContact CB-CE2 3.74Å
457L98.1Very high97.5Very high2 Ų221.3 Ų21.31%0.0111%0.107CC..Hα-helixtrans-73.7-26.3179.6-63.3-177.7000113.6I443 T453 L454 Y455 P461 V523 K525 L527I443-L457 HydrophobicContact CG2-CD2 4.48Å; T453-L457 WeakPolarHBondContact O-CG 3.14Å; T453-L457 PolarHBondContact O-N 3.19Å; T453-L457 VanDerWaalsContact O-N 3.14Å; L454-L457 PolarHBondContact O-N 2.93Å; Y455-L457 VanDerWaalsContact C-N 3.32Å; Y455-L457 PolarHBondContact O-N 3.33Å; L457-P461 WeakPolarHBondContact O-CB 3.37Å; L457-V523 HydrophobicContact CB-CG1 4.11Å; L457-V523 HydrophobicContact CB-CG2 4.3Å; L457-V523 HydrophobicContact CD1-CG1 4.47Å; L457-K525 HydrophobicContact CD2-CB 4.19Å; L457-L527 HydrophobicContact CD1-CB 4.33Å; L457-L527 HydrophobicContact CD1-CD1 3.86Å; L457-L527 HydrophobicContact CD1-CD2 4.49Å; L457-L527 HydrophobicContact CD1-CG 4.44Å
458A98.2Very high97.6Very high0 Ų020.2 Ų20.20%010%0.099CC..Hα-helixtrans-89.9-35.5-178.800000113.5L454 Y455 Q519 N522 V523L454-A458 VanDerWaalsContact O-CB 3.24Å; L454-A458 WeakPolarHBondContact O-CB 3.32Å; L454-A458 PolarHBondContact O-N 2.96Å; Y455-A458 PolarHBondContact O-N 3.36Å; A458-Q519 HydrophobicContact CB-CB 3.96Å; A458-N522 WeakPolarHBondContact O-CB 3.47Å; A458-N522 PolarHBondContact O-ND2 3.17Å; A458-V523 HydrophobicContact CB-CG2 3.86Å
459Y97.4Very high97.6Very high60 Ų6020.2 Ų20.224%0.23510%0.099CC..Hα-helixtrans-107.5-20.3-175.4-74.4-95.6000113.8Y455 P461 K513 S515 R518 Q519Y455-Y459 HydrophobicContact CD1-CD2 4.27Å; Y455-Y459 HydrophobicContact CD1-CG 4.44Å; Y455-Y459 AromaticContact CD2-CD2 3.61Å; Y455-Y459 HydrophobicContact CD2-CD2 3.61Å; Y455-Y459 AromaticContact CD2-CE2 3.87Å; Y455-Y459 HydrophobicContact CD2-CE2 3.87Å; Y455-Y459 HydrophobicContact CD2-CG 4.35Å; Y455-Y459 HydrophobicContact CE1-CD2 4.17Å; Y455-Y459 AromaticContact CE1-CG 3.98Å; Y455-Y459 HydrophobicContact CE1-CG 3.98Å; Y455-Y459 HydrophobicContact CE2-CD1 4.33Å; Y455-Y459 AromaticContact CE2-CD2 3.43Å; Y455-Y459 HydrophobicContact CE2-CD2 3.43Å; Y455-Y459 VanDerWaalsContact CE2-CD2 3.43Å; Y455-Y459 HydrophobicContact CE2-CE1 4.47Å; Y455-Y459 AromaticContact CE2-CE2 3.6Å; Y455-Y459 HydrophobicContact CE2-CE2 3.6Å; Y455-Y459 AromaticContact CE2-CG 3.84Å; Y455-Y459 HydrophobicContact CE2-CG 3.84Å; Y455-Y459 HydrophobicContact CG-CD2 4.03Å; Y455-Y459 AromaticContact CZ-CD2 3.73Å; Y455-Y459 AromaticContact CZ-CG 3.63Å; Y455-Y459 WeakPolarHBondContact O-CB 3.43Å; Y455-Y459 PolarHBondContact O-N 2.72Å; Y459-P461 VanDerWaalsContact C-CD 3.5Å; Y459-K513 PolarHBondContact OH-O 2.66Å; Y459-S515 PolarHBondContact OH-O 2.73Å; Y459-R518 PolarHBondContact OH-NE 2.95Å; Y459-Q519 HydrophobicContact CD1-CG 4.23Å; Y459-Q519 HydrophobicContact CD2-CB 4.28Å; Y459-Q519 HydrophobicContact CD2-CG 4.33Å; Y459-Q519 HydrophobicContact CE1-CG 3.58Å; Y459-Q519 HydrophobicContact CE2-CB 3.85Å; Y459-Q519 HydrophobicContact CE2-CG 3.69Å; Y459-Q519 VanDerWaalsContact OH-CG 3.29Å; Y459-Q519 WeakPolarHBondContact OH-CG 3.38Å
460T95.2Very high97.6Very high35 Ų3521.2 Ų21.222%0.21510%0.104CC..SBendtrans-133.555.4175.756.30000111.9A456 D462 K463A456-T460 WeakPolarHBondContact CA-OG1 3.39Å; A456-T460 CarbonylContact O-C 3.58Å; A456-T460 VanDerWaalsContact O-CA 3.25Å; A456-T460 WeakPolarHBondContact O-CA 3.26Å; A456-T460 PolarHBondContact O-N 2.86Å; A456-T460 VanDerWaalsContact O-O 3.07Å; A456-T460 PolarHBondContact O-OG1 2.83Å; T460-D462 PolarHBondContact O-N 2.87Å; T460-K463 HydrophobicContact CG2-CD 4.34Å; T460-K463 PolarHBondContact O-N 2.81Å; T460-K463 VanDerWaalsContact O-N 3.1Å
461P94.9Very high97.5Very high29 Ų2921.2 Ų21.219%0.18810%0.104CC..THydrogen-bonded Turntrans-61.4-15.4-165.425.1-36.4000115.6L457 Y459 K525L457-P461 WeakPolarHBondContact O-CB 3.37Å; Y459-P461 VanDerWaalsContact C-CD 3.5Å; P461-K525 VanDerWaalsContact O-CE 3.28Å; P461-K525 WeakPolarHBondContact O-CE 3.42Å; P461-K525 WeakPolarHBondContact O-CG 3.34Å
462D94.3Very high97.5Very high139 Ų13921.2 Ų21.274%0.74311%0.105SC*.THydrogen-bonded Turntrans-90.3-12.4-177.7-58.1-47000113.6T460T460-D462 PolarHBondContact O-N 2.87Å
463K94.2Very high97.5Very high75 Ų7521.4 Ų21.433%0.32611%0.105SC..SBendtrans-77.6-29.8-174.2-69.3-167.4178.4-165.90114.2N424 M441 T460N424-K463 HydrophobicContact CB-CD 4.38Å; N424-K463 VanDerWaalsContact CG-NZ 3.34Å; N424-K463 PolarHBondContact ND2-NZ 3.33Å; N424-K463 VanDerWaalsContact ND2-NZ 3.15Å; M441-K463 WeakPolarHBondContact CE-O 3.29Å; T460-K463 HydrophobicContact CG2-CD 4.34Å; T460-K463 PolarHBondContact O-N 2.81Å; T460-K463 VanDerWaalsContact O-N 3.1Å
464Y97Very high97.5Very high0 Ų021.4 Ų21.40%011%0.105CC..  trans-125.3149.1-175.3-59.8-79.6000110.2N364 N424 F427 M441 I443 A456 K525N364-Y464 HydrophobicContact CB-CE1 4.17Å; N364-Y464 PolarHBondContact ND2-OH 2.78Å; N424-Y464 PolarHBondContact OD1-OH 2.86Å; F427-Y464 HydrophobicContact CG-CE1 4.42Å; M441-Y464 HydrophobicContact CB-CD1 4.22Å; M441-Y464 CarbonylContact O-C 3.59Å; I443-Y464 HydrophobicContact CB-CD1 3.74Å; I443-Y464 HydrophobicContact CB-CD2 4.2Å; I443-Y464 HydrophobicContact CB-CE1 3.75Å; I443-Y464 HydrophobicContact CB-CE2 4.23Å; I443-Y464 HydrophobicContact CB-CG 3.96Å; I443-Y464 HydrophobicContact CD1-CE2 4.05Å; I443-Y464 HydrophobicContact CG2-CD1 4.03Å; I443-Y464 HydrophobicContact CG2-CD2 3.85Å; I443-Y464 HydrophobicContact CG2-CE1 4.43Å; I443-Y464 HydrophobicContact CG2-CE2 4.28Å; I443-Y464 HydrophobicContact CG2-CG 3.72Å; A456-Y464 HydrophobicContact CB-CD2 3.91Å; A456-Y464 HydrophobicContact CB-CE2 3.74Å; Y464-K525 WeakPolarHBondContact O-CD 3.28Å; Y464-K525 VanDerWaalsContact O-CE 3.25Å; Y464-K525 WeakPolarHBondContact O-CE 3.49Å; Y464-K525 VanDerWaalsContact O-CG 3.3Å; Y464-K525 WeakPolarHBondContact O-CG 3.11Å
465Q97.4Very high97.4Very high52 Ų5222.6 Ų22.624%0.24311%0.112CC..SBendtrans-87.6-21.5178.7-59.5-51.2-27.900113.2N439 M441 P526 C589 L590N439-Q465 WeakPolarHBondContact O-CG 3.21Å; N439-Q465 PolarHBondContact O-NE2 3.27Å; M441-Q465 PolarHBondContact O-N 2.99Å; Q465-P526 WeakPolarHBondContact O-CD 3.41Å; Q465-C589 HydrophobicContact CB-CB 4.42Å; Q465-L590 HydrophobicContact CB-CD2 4.07Å; Q465-L590 HydrophobicContact CG-CD2 4.36Å
466C98.2Very high97.3Very high0 Ų021.3 Ų21.30%011%0.107CC..EExtended strand (participates in β ladder)trans-166.2170.4177.746.30000109.5A442 I443 P526 L585 C589A442-C466 WeakPolarHBondContact CA-O 3.46Å; A442-C466 WeakPolarHBondContact CB-O 3.47Å; A442-C466 VanDerWaalsContact CB-SG 3.59Å; I443-C466 PolarHBondContact N-O 3.15Å; C466-P526 CarbonylContact C-O 3.56Å; C466-P526 WeakPolarHBondContact CA-O 3.38Å; C466-P526 HydrophobicContact CB-CB 4.14Å; C466-P526 VanDerWaalsContact CB-O 3.28Å; C466-P526 WeakPolarHBondContact CB-O 3.36Å; C466-L585 HydrophobicContact CB-CD1 4.33Å; C466-L585 HydrophobicContact CB-CD2 4.46Å; C466-L585 HydrophobicContact CB-CG 4.36Å; C466-C589 HydrophobicContact CB-CB 3.65Å; C466-C589 WeakPolarHBondContact CB-SG 3.37Å; C466-C589 WeakPolarHBondContact SG-CB 3.12Å; C466-C589 CovalentContact SG-SG 2.03Å; C466-C589 PolarHBondContact SG-SG 2.83Å
467G98.5Very high97.3Very high0 Ų022.7 Ų22.70%011%0.114CC..EExtended strand (participates in β ladder)trans-154.6167.1170.600000115.6I443 P526 L527 L528 L585I443-G467 CarbonylContact O-C 3.6Å; I443-G467 WeakPolarHBondContact O-CA 3.49Å; G467-P526 PolarHBondContact N-O 3.06Å; G467-L527 CarbonylContact O-C 3.48Å; G467-L527 WeakPolarHBondContact O-CA 3.44Å; G467-L527 WeakPolarHBondContact O-CD1 3.48Å; G467-L528 PolarHBondContact O-N 2.97Å; G467-L585 WeakPolarHBondContact O-CD2 3.38Å
468V98.8Very high97.2Very high0 Ų024.4 Ų24.40%012%0.122CC..EExtended strand (participates in β ladder)trans-128.7118.1179.4179.70000108.7I443 M444 G445 T453 L528 Y578 I582 L585 F586I443-V468 PolarHBondContact O-N 2.95Å; M444-V468 VanDerWaalsContact CA-O 3.25Å; M444-V468 WeakPolarHBondContact CA-O 3.43Å; M444-V468 HydrophobicContact CB-CB 3.68Å; M444-V468 HydrophobicContact CB-CG2 4.32Å; G445-V468 PolarHBondContact N-O 3.46Å; T453-V468 WeakPolarHBondContact CG2-O 3.3Å; T453-V468 PolarHBondContact OG1-O 3.25Å; V468-L528 CarbonylContact C-O 3.21Å; V468-L528 WeakPolarHBondContact CA-O 3.5Å; V468-L528 HydrophobicContact CG1-CD2 4.17Å; V468-L528 HydrophobicContact CG2-CB 4.34Å; V468-Y578 HydrophobicContact CG1-CE2 4.18Å; V468-Y578 WeakPolarHBondContact CG1-OH 3.33Å; V468-I582 HydrophobicContact CG1-CD1 4.07Å; V468-I582 HydrophobicContact CG1-CG1 4.02Å; V468-I582 HydrophobicContact CG2-CG1 4.11Å; V468-I582 HydrophobicContact CG2-CG2 4.46Å; V468-L585 HydrophobicContact CG2-CD2 3.74Å; V468-F586 HydrophobicContact CG2-CE1 3.73Å; V468-F586 HydrophobicContact CG2-CZ 3.63Å
469A98.7Very high97.1Very high0 Ų024.8 Ų24.80%013%0.125CC..EExtended strand (participates in β ladder)trans-117.4111.3179.900000110.1T453 L454 A472 L527 L528 I529 A530T453-A469 HydrophobicContact CG2-CB 4.15Å; L454-A469 HydrophobicContact CD1-CB 4.49Å; L454-A469 HydrophobicContact CD2-CB 3.58Å; L454-A469 HydrophobicContact CG-CB 3.76Å; A469-A472 HydrophobicContact CB-CB 3.98Å; A469-L527 HydrophobicContact CB-CD1 4.26Å; A469-L528 PolarHBondContact N-O 2.8Å; A469-I529 WeakPolarHBondContact O-CA 3.46Å; A469-A530 PolarHBondContact O-N 3.17Å
470E98.3Very high96.9Very high21 Ų2122.1 Ų22.110%0.09811%0.114CC..EExtended strand (participates in β ladder)trans-100.8135.1173.9178.1-170.317100110.6G445 A446 S447 A472 A530 C568 I569G445-E470 PolarHBondContact O-N 2.89Å; A446-E470 CarbonylContact C-O 3.54Å; A446-E470 VanDerWaalsContact CA-O 3.27Å; A446-E470 WeakPolarHBondContact CA-O 3.49Å; A446-E470 HydrophobicContact CB-CB 3.85Å; A446-E470 HydrophobicContact CB-CG 4.05Å; A446-E470 WeakPolarHBondContact CB-OE2 3.23Å; S447-E470 PolarHBondContact N-O 3.24Å; E470-A472 PolarHBondContact O-N 2.83Å; E470-A530 CarbonylContact C-O 3.51Å; E470-A530 WeakPolarHBondContact CA-O 3.47Å; E470-C568 WeakPolarHBondContact OE1-CA 3.14Å; E470-I569 PolarHBondContact OE1-N 2.83Å
471C97.7Very high96.8Very high0 Ų026 Ų260%013%0.13CC..SBendtrans46.244.1172.7-60.80000112.8S447 P473 A530 H531S447-C471 WeakPolarHBondContact CA-O 3.25Å; C471-P473 WeakPolarHBondContact O-CD 3.29Å; C471-A530 PolarHBondContact N-O 2.89Å; C471-H531 WeakPolarHBondContact CA-ND1 3.43Å
472A98.2Very high96.7Very high1 Ų126.2 Ų26.21%0.00813%0.132CC..  trans-89.1124-161.800000112.4G450 L454 A469 E470 S474G450-A472 VanDerWaalsContact C-CB 3.43Å; L454-A472 HydrophobicContact CD1-CB 3.61Å; L454-A472 HydrophobicContact CG-CB 4.12Å; A469-A472 HydrophobicContact CB-CB 3.98Å; E470-A472 PolarHBondContact O-N 2.83Å; A472-S474 PolarHBondContact O-N 3.04Å
473P97.9Very high96.4Very high3 Ų320.4 Ų20.42%0.01910%0.101CC..  trans-62.391.1169.8-22.433.7000111.3W415 S447 F451 C471 L476 T479 V538W415-P473 HydrophobicContact CZ3-CB 4.24Å; W415-P473 HydrophobicContact CZ3-CG 4.22Å; S447-P473 WeakPolarHBondContact O-CD 3.38Å; F451-P473 HydrophobicContact CB-CB 4.35Å; F451-P473 HydrophobicContact CB-CG 4.4Å; F451-P473 VanDerWaalsContact CD2-O 3.27Å; F451-P473 WeakPolarHBondContact CD2-O 3.27Å; C471-P473 WeakPolarHBondContact O-CD 3.29Å; P473-L476 HydrophobicContact CB-CD2 4Å; P473-T479 HydrophobicContact CB-CG2 4.09Å; P473-T479 WeakPolarHBondContact CB-OG1 3.16Å; P473-T479 HydrophobicContact CG-CG2 4.43Å; P473-V538 HydrophobicContact CG-CG1 4.3Å; P473-V538 HydrophobicContact CG-CG2 3.86Å
474S98.2Very high95.9Very high0 Ų017.3 Ų17.30%09%0.089CC..SBendtrans-83.2-25.3179.871.30000112.8A472 S515 P516 L517 A542A472-S474 PolarHBondContact O-N 3.04Å; S474-S515 WeakPolarHBondContact O-CB 3.41Å; S474-P516 VanDerWaalsContact O-CD 3.27Å; S474-P516 WeakPolarHBondContact O-CD 3.49Å; S474-L517 VanDerWaalsContact O-CB 3.23Å; S474-L517 WeakPolarHBondContact O-CB 3.32Å; S474-L517 PolarHBondContact O-N 2.94Å; S474-A542 VanDerWaalsContact OG-C 3.25Å; S474-A542 PolarHBondContact OG-O 2.84Å
475D97.8Very high95.1Very high28 Ų2825.2 Ų25.215%0.1512%0.118CC..  trans-126.1109.7176-177.62.5000110I477 E478 T479 S515 L517D475-I477 VanDerWaalsContact C-N 3.27Å; D475-I477 PolarHBondContact O-N 3.42Å; D475-I477 WeakPolarHBondContact OD1-CB 3.35Å; D475-I477 PolarHBondContact OD1-N 2.88Å; D475-E478 HydrophobicContact CB-CB 4.14Å; D475-E478 PolarHBondContact O-N 3.09Å; D475-T479 WeakPolarHBondContact O-CB 3.26Å; D475-T479 PolarHBondContact O-N 2.78Å; D475-T479 PolarHBondContact O-OG1 2.64Å; D475-S515 PolarHBondContact OD1-OG 2.78Å; D475-L517 HydrophobicContact CB-CD2 3.97Å
476L97.2Very high94Very high2 Ų226.1 Ų26.11%0.0112%0.122CC..Hα-helixtrans-71.6-20.4-178.1-57.4-164.8000113.2W415 F451 P473 M480 F498 L511 V514 S515W415-L476 HydrophobicContact CB-CD1 4.32Å; W415-L476 HydrophobicContact CE3-CD1 4.15Å; W415-L476 HydrophobicContact CE3-CD2 3.84Å; W415-L476 HydrophobicContact CZ3-CD2 3.9Å; F451-L476 HydrophobicContact CD2-CD2 3.73Å; F451-L476 HydrophobicContact CD2-CG 4.49Å; F451-L476 HydrophobicContact CE2-CD1 3.94Å; F451-L476 HydrophobicContact CE2-CD2 3.75Å; F451-L476 HydrophobicContact CE2-CG 4.03Å; F451-L476 HydrophobicContact CZ-CD1 4.45Å; P473-L476 HydrophobicContact CB-CD2 4Å; L476-M480 WeakPolarHBondContact O-CG 3.36Å; L476-M480 PolarHBondContact O-N 2.81Å; L476-M480 VanDerWaalsContact O-N 3.09Å; L476-F498 HydrophobicContact CB-CE1 4.37Å; L476-F498 HydrophobicContact CD1-CD1 4.26Å; L476-F498 HydrophobicContact CD1-CE1 4.3Å; L476-F498 HydrophobicContact CD2-CE1 4.18Å; L476-L511 HydrophobicContact CB-CB 4.08Å; L476-L511 HydrophobicContact CB-CD2 3.89Å; L476-L511 HydrophobicContact CD1-CD2 4.4Å; L476-V514 HydrophobicContact CD1-CG2 3.64Å; L476-S515 PolarHBondContact N-OG 3.48Å
477I97.2Very high93.3Very high30 Ų3029.3 Ų29.315%0.15414%0.135CC..Hα-helixtrans-68.7-55.7172.7-62.2175.6000109.2D475 T479 M480 Q481 K508 L511 W512D475-I477 VanDerWaalsContact C-N 3.27Å; D475-I477 PolarHBondContact O-N 3.42Å; D475-I477 WeakPolarHBondContact OD1-CB 3.35Å; D475-I477 PolarHBondContact OD1-N 2.88Å; I477-T479 PolarHBondContact O-N 3.34Å; I477-M480 PolarHBondContact O-N 3.32Å; I477-Q481 HydrophobicContact CG2-CG 4.4Å; I477-Q481 WeakPolarHBondContact O-CB 3.47Å; I477-Q481 WeakPolarHBondContact O-CG 3.17Å; I477-Q481 PolarHBondContact O-N 2.93Å; I477-K508 HydrophobicContact CD1-CB 3.95Å; I477-K508 HydrophobicContact CD1-CG 4.32Å; I477-K508 HydrophobicContact CG1-CB 4.46Å; I477-L511 HydrophobicContact CG1-CB 3.82Å; I477-L511 HydrophobicContact CG1-CD1 4.43Å; I477-W512 HydrophobicContact CD1-CB 3.92Å
478E96.1Very high92.6Very high38 Ų3833.6 Ų33.618%0.17816%0.158CC..Hα-helixtrans-56.5-41.8175.7172.763.9-17100110.5D475 M480 Q481 S482 S539 K541D475-E478 HydrophobicContact CB-CB 4.14Å; D475-E478 PolarHBondContact O-N 3.09Å; E478-M480 PolarHBondContact O-N 3.3Å; E478-Q481 PolarHBondContact O-N 3.36Å; E478-S482 VanDerWaalsContact O-CB 3.23Å; E478-S482 WeakPolarHBondContact O-CB 3.23Å; E478-S482 PolarHBondContact O-N 3.22Å; E478-S482 PolarHBondContact O-OG 3.39Å; E478-S539 PolarHBondContact OE1-OG 3.06Å; E478-S539 VanDerWaalsContact OE1-OG 3.05Å; E478-K541 WeakPolarHBondContact OE1-CD 3.31Å
479T95.2Very high91.9Very high8 Ų835.9 Ų35.95%0.04917%0.169CC..Hα-helixtrans-58.3-45.8178.8-57.10000111.7P473 D475 I477 M483 F498P473-T479 HydrophobicContact CB-CG2 4.09Å; P473-T479 WeakPolarHBondContact CB-OG1 3.16Å; P473-T479 HydrophobicContact CG-CG2 4.43Å; D475-T479 WeakPolarHBondContact O-CB 3.26Å; D475-T479 PolarHBondContact O-N 2.78Å; D475-T479 PolarHBondContact O-OG1 2.64Å; I477-T479 PolarHBondContact O-N 3.34Å; T479-M483 WeakPolarHBondContact O-CG 3.39Å; T479-M483 PolarHBondContact O-N 2.75Å; T479-F498 HydrophobicContact CG2-CZ 4.23Å
480M94.4Very high91.5Very high3 Ų337.3 Ų37.32%0.01518%0.182CC..Hα-helixtrans-70.4-36177.5-73-165.177.900112.9L476 I477 E478 M483 Y491 K495 F498 A500 A502 L511L476-M480 WeakPolarHBondContact O-CG 3.36Å; L476-M480 PolarHBondContact O-N 2.81Å; L476-M480 VanDerWaalsContact O-N 3.09Å; I477-M480 PolarHBondContact O-N 3.32Å; E478-M480 PolarHBondContact O-N 3.3Å; M480-M483 HydrophobicContact CG-CE 4.11Å; M480-Y491 HydrophobicContact CE-CE2 4.11Å; M480-K495 HydrophobicContact CE-CG 4.04Å; M480-F498 HydrophobicContact CG-CD1 4.09Å; M480-F498 HydrophobicContact CG-CE1 4.16Å; M480-F498 HydrophobicContact CG-CG 4.31Å; M480-F498 HydrophobicContact CG-CZ 4.46Å; M480-F498 HydrophobicContact SD-CB 4.05Å; M480-F498 HydrophobicContact SD-CD1 4.1Å; M480-F498 HydrophobicContact SD-CG 4.01Å; M480-A500 WeakPolarHBondContact CE-O 3.46Å; M480-A502 HydrophobicContact CB-CB 3.68Å; M480-A502 HydrophobicContact SD-CB 4.35Å; M480-L511 HydrophobicContact CG-CD1 4.4Å; M480-L511 HydrophobicContact SD-CD1 3.49Å; M480-L511 WeakPolarHBondContact SD-CD1 3.25Å; M480-L511 HydrophobicContact SD-CD2 3.77Å; M480-L511 HydrophobicContact SD-CG 4.28Å
481Q93.1Very high91.2Very high116 Ų11637.9 Ų37.954%0.54218%0.183SC..Hα-helixtrans-76.6-27.5-178.8-70.6177.7-14.900113.6I477 E478 A502I477-Q481 HydrophobicContact CG2-CG 4.4Å; I477-Q481 WeakPolarHBondContact O-CB 3.47Å; I477-Q481 WeakPolarHBondContact O-CG 3.17Å; I477-Q481 PolarHBondContact O-N 2.93Å; E478-Q481 PolarHBondContact O-N 3.36Å; Q481-A502 HydrophobicContact CG-CB 3.94Å
482S91.9Very high91.1Very high34 Ų3438.1 Ų38.124%0.23819%0.185CC..THydrogen-bonded Turntrans-99.35.9-178.665.30000113.9E478 S539E478-S482 VanDerWaalsContact O-CB 3.23Å; E478-S482 WeakPolarHBondContact O-CB 3.23Å; E478-S482 PolarHBondContact O-N 3.22Å; E478-S482 PolarHBondContact O-OG 3.39Å; S482-S539 WeakPolarHBondContact OG-CB 3.41Å
483M88Confident90.9Very high17 Ų1738.7 Ų38.78%0.08419%0.189CC..  trans-52.1142.7178.6-72.8-165.617800111.4T479 M480 R485 W487 Y491 Y494 F498T479-M483 WeakPolarHBondContact O-CG 3.39Å; T479-M483 PolarHBondContact O-N 2.75Å; M480-M483 HydrophobicContact CG-CE 4.11Å; M483-R485 PolarHBondContact O-N 3.24Å; M483-W487 HydrophobicContact CB-CE3 4.33Å; M483-W487 HydrophobicContact CG-CE3 4.31Å; M483-W487 HydrophobicContact SD-CE3 4.07Å; M483-Y491 HydrophobicContact SD-CD2 4.43Å; M483-Y491 HydrophobicContact SD-CE2 4.41Å; M483-Y494 HydrophobicContact CE-CD1 3.74Å; M483-Y494 HydrophobicContact CE-CE1 4.4Å; M483-Y494 HydrophobicContact CE-CG 4.02Å; M483-Y494 HydrophobicContact SD-CD1 3.97Å; M483-Y494 HydrophobicContact SD-CD2 4.21Å; M483-Y494 HydrophobicContact SD-CE1 4.4Å; M483-Y494 HydrophobicContact SD-CG 3.86Å; M483-F498 HydrophobicContact CE-CD2 4.34Å; M483-F498 HydrophobicContact CE-CE2 3.58Å; M483-F498 HydrophobicContact CE-CZ 3.91Å
484P83.4Confident90.8Very high11 Ų1140.1 Ų40.17%0.07119%0.194CC..  trans-55.6137.4177.98-16.4000110.3E486 W487 D536P484-E486 VanDerWaalsContact CB-OE2 3.29Å; P484-E486 WeakPolarHBondContact CB-OE2 3.47Å; P484-E486 PolarHBondContact O-N 3.01Å; P484-W487 HydrophobicContact CG-CD2 3.63Å; P484-W487 HydrophobicContact CG-CE3 3.94Å; P484-W487 HydrophobicContact CG-CG 4.07Å; P484-W487 HydrophobicContact CG-CH2 4.19Å; P484-W487 HydrophobicContact CG-CZ2 3.9Å; P484-W487 HydrophobicContact CG-CZ3 4.2Å; P484-W487 WeakPolarHBondContact O-CB 3.42Å; P484-W487 PolarHBondContact O-N 2.8Å; P484-D536 WeakPolarHBondContact CB-O 3.41Å; P484-D536 VanDerWaalsContact CD-O 3.26Å; P484-D536 WeakPolarHBondContact CD-O 3.37Å; P484-D536 WeakPolarHBondContact CG-O 3.28Å
485R80.2Confident90.7Very high165 Ų16541.4 Ų41.462%0.62320%0.2SC*.G310 helixtrans-56.8-32.2-174.7-68.4-176.6173.6-175.9-0.5111.2V105 M483 W487 N488V105-R485 WeakPolarHBondContact CG1-O 3.42Å; V105-R485 HydrophobicContact CG2-CB 3.5Å; V105-R485 VanDerWaalsContact CG2-CB 3.5Å; V105-R485 WeakPolarHBondContact CG2-O 3.28Å; M483-R485 PolarHBondContact O-N 3.24Å; R485-W487 PolarHBondContact O-N 2.96Å; R485-N488 VanDerWaalsContact O-CB 3.23Å; R485-N488 WeakPolarHBondContact O-CB 3.48Å; R485-N488 PolarHBondContact O-N 3.09Å; R485-N488 PolarHBondContact O-ND2 3.31Å
486E75.4Confident90.7Very high71 Ų7142.4 Ų42.433%0.33221%0.207SC..G310 helixtrans-52-26.7176.4-65.371.9-154.700112.4P484P484-E486 VanDerWaalsContact CB-OE2 3.29Å; P484-E486 WeakPolarHBondContact CB-OE2 3.47Å; P484-E486 PolarHBondContact O-N 3.01Å
487W82.8Confident90.7Very high68 Ų6843.8 Ų43.826%0.25821%0.212SC..G310 helixtrans-89.9-7.3-177.4-63.14.1000113.3M483 P484 R485 L489 A490 Y491 Y494 R537M483-W487 HydrophobicContact CB-CE3 4.33Å; M483-W487 HydrophobicContact CG-CE3 4.31Å; M483-W487 HydrophobicContact SD-CE3 4.07Å; P484-W487 HydrophobicContact CG-CD2 3.63Å; P484-W487 HydrophobicContact CG-CE3 3.94Å; P484-W487 HydrophobicContact CG-CG 4.07Å; P484-W487 HydrophobicContact CG-CH2 4.19Å; P484-W487 HydrophobicContact CG-CZ2 3.9Å; P484-W487 HydrophobicContact CG-CZ3 4.2Å; P484-W487 WeakPolarHBondContact O-CB 3.42Å; P484-W487 PolarHBondContact O-N 2.8Å; R485-W487 PolarHBondContact O-N 2.96Å; W487-L489 PolarHBondContact O-N 3.18Å; W487-A490 CarbonylContact O-C 3.56Å; W487-A490 WeakPolarHBondContact O-CA 3.49Å; W487-A490 PolarHBondContact O-N 3.29Å; W487-Y491 PolarHBondContact O-N 2.83Å; W487-Y491 VanDerWaalsContact O-N 3.16Å; W487-Y494 HydrophobicContact CB-CE2 3.82Å; W487-Y494 HydrophobicContact CD2-CE2 4.21Å; W487-Y494 AromaticContact CD2-CZ 3.77Å; W487-Y494 VanDerWaalsContact CD2-OH 3.23Å; W487-Y494 AromaticContact CE3-CE1 3.81Å; W487-Y494 HydrophobicContact CE3-CE1 3.81Å; W487-Y494 HydrophobicContact CE3-CE2 4.05Å; W487-Y494 AromaticContact CE3-CZ 3.43Å; W487-Y494 VanDerWaalsContact CE3-CZ 3.43Å; W487-Y494 VanDerWaalsContact CE3-OH 3.25Å; W487-Y494 HydrophobicContact CG-CE2 4.16Å; W487-Y494 HydrophobicContact CZ3-CE1 4.03Å; W487-R537 HydrophobicContact CH2-CB 4.06Å; W487-R537 HydrophobicContact CH2-CG 4.12Å; W487-R537 HydrophobicContact CZ2-CG 4.16Å
488N83.6Confident90.7Very high90 Ų9042.7 Ų42.748%0.48121%0.206SC..G310 helixtrans-59.1-34.9-177.1-72.8-9.3000112.8R485 A490 Y491R485-N488 VanDerWaalsContact O-CB 3.23Å; R485-N488 WeakPolarHBondContact O-CB 3.48Å; R485-N488 PolarHBondContact O-N 3.09Å; R485-N488 PolarHBondContact O-ND2 3.31Å; N488-A490 PolarHBondContact O-N 3.34Å; N488-Y491 WeakPolarHBondContact O-CB 3.21Å; N488-Y491 PolarHBondContact O-N 3.41Å; N488-Y491 VanDerWaalsContact O-N 3.15Å
489L85.8Confident90.7Very high47 Ų4743.1 Ų43.125%0.24622%0.22CC..G310 helixtrans-68.5-10.7177-66.9175.7000113.6V105 I106 V145 W487V105-L489 HydrophobicContact CG1-CD1 4.02Å; V105-L489 HydrophobicContact CG1-CG 3.88Å; I106-L489 HydrophobicContact CG1-CD1 3.97Å; V145-L489 VanDerWaalsContact CB-O 3.3Å; V145-L489 WeakPolarHBondContact CB-O 3.32Å; V145-L489 WeakPolarHBondContact CG2-O 3.5Å; W487-L489 PolarHBondContact O-N 3.18Å
490A89.3Confident90.8Very high31 Ų3143.4 Ų43.426%0.25622%0.223SC..G310 helixtrans-120.114.3175.100000112.1V145 W487 N488 G492 V493 Y494V145-A490 HydrophobicContact CG2-CB 4.39Å; W487-A490 CarbonylContact O-C 3.56Å; W487-A490 WeakPolarHBondContact O-CA 3.49Å; W487-A490 PolarHBondContact O-N 3.29Å; N488-A490 PolarHBondContact O-N 3.34Å; A490-G492 VanDerWaalsContact C-N 3.26Å; A490-G492 PolarHBondContact O-N 2.9Å; A490-V493 WeakPolarHBondContact O-CB 3.35Å; A490-V493 PolarHBondContact O-N 2.89Å; A490-Y494 HydrophobicContact CB-CE2 4.37Å; A490-Y494 WeakPolarHBondContact O-CD2 3.27Å; A490-Y494 PolarHBondContact O-N 2.86Å
491Y92.1Very high90.9Very high32 Ų3243.9 Ų43.913%0.12523%0.227CC..Hα-helixtrans-58.8-35.8-172.7-172-109.7000113.2M480 M483 W487 N488 V493 Y494 K495 E503M480-Y491 HydrophobicContact CE-CE2 4.11Å; M483-Y491 HydrophobicContact SD-CD2 4.43Å; M483-Y491 HydrophobicContact SD-CE2 4.41Å; W487-Y491 PolarHBondContact O-N 2.83Å; W487-Y491 VanDerWaalsContact O-N 3.16Å; N488-Y491 WeakPolarHBondContact O-CB 3.21Å; N488-Y491 PolarHBondContact O-N 3.41Å; N488-Y491 VanDerWaalsContact O-N 3.15Å; Y491-V493 VanDerWaalsContact C-N 3.28Å; Y491-V493 PolarHBondContact O-N 2.99Å; Y491-Y494 WeakPolarHBondContact O-CA 3.39Å; Y491-Y494 WeakPolarHBondContact O-CB 3.35Å; Y491-Y494 PolarHBondContact O-N 3.13Å; Y491-K495 HydrophobicContact CD1-CD 4.15Å; Y491-K495 HydrophobicContact CD1-CG 4.19Å; Y491-K495 HydrophobicContact CE1-CD 3.81Å; Y491-K495 HydrophobicContact CE1-CG 3.94Å; Y491-K495 PolarHBondContact O-N 3.46Å; Y491-E503 HydrophobicContact CE1-CG 4.31Å
492G94.8Very high91Very high5 Ų538.5 Ų38.55%0.05220%0.203CC..Hα-helixtrans-56.8-38.9173.800000113.4E147 G149 A490 Y494 K495 V496E147-G492 WeakPolarHBondContact O-CA 3.47Å; G149-G492 WeakPolarHBondContact CA-O 3.42Å; A490-G492 VanDerWaalsContact C-N 3.26Å; A490-G492 PolarHBondContact O-N 2.9Å; G492-Y494 VanDerWaalsContact C-N 3.32Å; G492-Y494 PolarHBondContact O-N 3.37Å; G492-K495 WeakPolarHBondContact O-CB 3.17Å; G492-K495 PolarHBondContact O-N 3.38Å; G492-V496 PolarHBondContact O-N 2.87Å; G492-V496 VanDerWaalsContact O-N 3.15Å
493V95.6Very high91.1Very high14 Ų1442.3 Ų42.39%0.08522%0.216CC..Hα-helixtrans-65.9-37.1175.6169.10000110.9V145 A174 M178 A490 Y491 V496 R497V145-V493 HydrophobicContact CG1-CG2 3.75Å; A174-V493 HydrophobicContact CB-CG1 4.36Å; A174-V493 HydrophobicContact CB-CG2 4.2Å; M178-V493 HydrophobicContact CG-CG1 3.96Å; M178-V493 HydrophobicContact SD-CG1 3.65Å; A490-V493 WeakPolarHBondContact O-CB 3.35Å; A490-V493 PolarHBondContact O-N 2.89Å; Y491-V493 VanDerWaalsContact C-N 3.28Å; Y491-V493 PolarHBondContact O-N 2.99Å; V493-V496 PolarHBondContact O-N 3.35Å; V493-R497 HydrophobicContact CG1-CG 4.36Å; V493-R497 WeakPolarHBondContact O-CD 3.46Å; V493-R497 VanDerWaalsContact O-CG 3.23Å; V493-R497 WeakPolarHBondContact O-CG 3.32Å; V493-R497 PolarHBondContact O-N 3.38Å
494Y95.2Very high91.5Very high32 Ų3244.5 Ų44.513%0.12523%0.231CC..Hα-helixtrans-65.2-39.2173.7-70.9-81.2000112.1M483 W487 A490 Y491 G492 V496 R497 F498M483-Y494 HydrophobicContact CE-CD1 3.74Å; M483-Y494 HydrophobicContact CE-CE1 4.4Å; M483-Y494 HydrophobicContact CE-CG 4.02Å; M483-Y494 HydrophobicContact SD-CD1 3.97Å; M483-Y494 HydrophobicContact SD-CD2 4.21Å; M483-Y494 HydrophobicContact SD-CE1 4.4Å; M483-Y494 HydrophobicContact SD-CG 3.86Å; W487-Y494 HydrophobicContact CB-CE2 3.82Å; W487-Y494 HydrophobicContact CD2-CE2 4.21Å; W487-Y494 AromaticContact CD2-CZ 3.77Å; W487-Y494 VanDerWaalsContact CD2-OH 3.23Å; W487-Y494 AromaticContact CE3-CE1 3.81Å; W487-Y494 HydrophobicContact CE3-CE1 3.81Å; W487-Y494 HydrophobicContact CE3-CE2 4.05Å; W487-Y494 AromaticContact CE3-CZ 3.43Å; W487-Y494 VanDerWaalsContact CE3-CZ 3.43Å; W487-Y494 VanDerWaalsContact CE3-OH 3.25Å; W487-Y494 HydrophobicContact CG-CE2 4.16Å; W487-Y494 HydrophobicContact CZ3-CE1 4.03Å; A490-Y494 HydrophobicContact CB-CE2 4.37Å; A490-Y494 WeakPolarHBondContact O-CD2 3.27Å; A490-Y494 PolarHBondContact O-N 2.86Å; Y491-Y494 WeakPolarHBondContact O-CA 3.39Å; Y491-Y494 WeakPolarHBondContact O-CB 3.35Å; Y491-Y494 PolarHBondContact O-N 3.13Å; G492-Y494 VanDerWaalsContact C-N 3.32Å; G492-Y494 PolarHBondContact O-N 3.37Å; Y494-V496 VanDerWaalsContact C-N 3.3Å; Y494-V496 PolarHBondContact O-N 2.88Å; Y494-R497 PolarHBondContact O-N 3.43Å; Y494-R497 VanDerWaalsContact O-N 3.13Å; Y494-F498 HydrophobicContact CD1-CE2 4.34Å; Y494-F498 WeakPolarHBondContact O-CB 3.46Å; Y494-F498 VanDerWaalsContact O-CD2 3.32Å; Y494-F498 WeakPolarHBondContact O-CD2 3.27Å; Y494-F498 PolarHBondContact O-N 2.94Å
495K96.5Very high92.2Very high27 Ų2749.4 Ų49.412%0.11725%0.253CS..Hα-helixtrans-57.6-43.5173.7-67.1-166.4-80.6-165.70112.2E147 M480 Y491 G492 G499 A500 S501 E503E147-K495 WeakPolarHBondContact O-CE 3.29Å; E147-K495 PolarHBondContact O-NZ 2.98Å; E147-K495 IonicContact OE1-NZ 2.88Å; E147-K495 PolarHBondContact OE1-NZ 3.31Å; M480-K495 HydrophobicContact CE-CG 4.04Å; Y491-K495 HydrophobicContact CD1-CD 4.15Å; Y491-K495 HydrophobicContact CD1-CG 4.19Å; Y491-K495 HydrophobicContact CE1-CD 3.81Å; Y491-K495 HydrophobicContact CE1-CG 3.94Å; Y491-K495 PolarHBondContact O-N 3.46Å; G492-K495 WeakPolarHBondContact O-CB 3.17Å; G492-K495 PolarHBondContact O-N 3.38Å; K495-G499 CarbonylContact O-C 3.54Å; K495-G499 WeakPolarHBondContact O-CA 3.48Å; K495-G499 PolarHBondContact O-N 2.85Å; K495-A500 WeakPolarHBondContact CA-O 3.42Å; K495-A500 PolarHBondContact O-N 3.45Å; K495-S501 WeakPolarHBondContact CD-OG 3.43Å; K495-E503 IonicContact NZ-OE2 3.77Å; K495-E503 PolarHBondContact NZ-OE2 3.47Å
496V97.4Very high93Very high49 Ų4948.3 Ų48.330%0.29726%0.255SS..Hα-helixtrans-62.3-46.3174.4176.20000111.3D148 A174 F412 G492 V493 Y494 F498 G499D148-V496 WeakPolarHBondContact O-CG2 3.34Å; A174-V496 HydrophobicContact CB-CB 4.23Å; A174-V496 HydrophobicContact CB-CG1 4Å; A174-V496 HydrophobicContact CB-CG2 4.4Å; F412-V496 HydrophobicContact CD2-CG1 3.63Å; F412-V496 HydrophobicContact CE2-CG1 4.02Å; F412-V496 HydrophobicContact CG-CG1 4.28Å; G492-V496 PolarHBondContact O-N 2.87Å; G492-V496 VanDerWaalsContact O-N 3.15Å; V493-V496 PolarHBondContact O-N 3.35Å; Y494-V496 VanDerWaalsContact C-N 3.3Å; Y494-V496 PolarHBondContact O-N 2.88Å; V496-F498 PolarHBondContact O-N 3.43Å; V496-G499 PolarHBondContact O-N 3.34Å; V496-G499 VanDerWaalsContact O-N 3.17Å
497R96.6Very high94.1Very high31 Ų3145.2 Ų45.212%0.11724%0.242CC..Hα-helixtrans-64.7-40.1-178.1-70.2164.866.9-164.1-2.4113M178 N371 F412 G413 V493 Y494 G499M178-R497 HydrophobicContact CE-CG 4.46Å; M178-R497 HydrophobicContact SD-CG 4.16Å; N371-R497 PolarHBondContact OD1-NE 2.87Å; N371-R497 PolarHBondContact OD1-NH2 3.4Å; F412-R497 HydrophobicContact CD1-CG 4.08Å; F412-R497 HydrophobicContact CE1-CG 3.9Å; F412-R497 HydrophobicContact CZ-CG 4.48Å; G413-R497 PolarHBondContact N-O 3.22Å; V493-R497 HydrophobicContact CG1-CG 4.36Å; V493-R497 WeakPolarHBondContact O-CD 3.46Å; V493-R497 VanDerWaalsContact O-CG 3.23Å; V493-R497 WeakPolarHBondContact O-CG 3.32Å; V493-R497 PolarHBondContact O-N 3.38Å; Y494-R497 PolarHBondContact O-N 3.43Å; Y494-R497 VanDerWaalsContact O-N 3.13Å; R497-G499 VanDerWaalsContact C-N 3.33Å
498F96.9Very high94.9Very high8 Ų844.8 Ų44.84%0.03524%0.242CC..Hα-helixtrans-79.5-17175.6-81.6-103.6000112.6W415 L476 T479 M480 M483 Y494 V496 A500 F510 L511W415-F498 HydrophobicContact CE3-CE1 4.4Å; W415-F498 HydrophobicContact CH2-CE1 4.27Å; W415-F498 AromaticContact CH2-CZ 3.9Å; W415-F498 HydrophobicContact CH2-CZ 3.9Å; W415-F498 HydrophobicContact CZ2-CE1 4.42Å; W415-F498 HydrophobicContact CZ2-CE2 4.32Å; W415-F498 AromaticContact CZ2-CZ 3.98Å; W415-F498 HydrophobicContact CZ2-CZ 3.98Å; W415-F498 HydrophobicContact CZ3-CE1 4.26Å; W415-F498 HydrophobicContact CZ3-CZ 4.33Å; L476-F498 HydrophobicContact CB-CE1 4.37Å; L476-F498 HydrophobicContact CD1-CD1 4.26Å; L476-F498 HydrophobicContact CD1-CE1 4.3Å; L476-F498 HydrophobicContact CD2-CE1 4.18Å; T479-F498 HydrophobicContact CG2-CZ 4.23Å; M480-F498 HydrophobicContact CG-CD1 4.09Å; M480-F498 HydrophobicContact CG-CE1 4.16Å; M480-F498 HydrophobicContact CG-CG 4.31Å; M480-F498 HydrophobicContact CG-CZ 4.46Å; M480-F498 HydrophobicContact SD-CB 4.05Å; M480-F498 HydrophobicContact SD-CD1 4.1Å; M480-F498 HydrophobicContact SD-CG 4.01Å; M483-F498 HydrophobicContact CE-CD2 4.34Å; M483-F498 HydrophobicContact CE-CE2 3.58Å; M483-F498 HydrophobicContact CE-CZ 3.91Å; Y494-F498 HydrophobicContact CD1-CE2 4.34Å; Y494-F498 WeakPolarHBondContact O-CB 3.46Å; Y494-F498 VanDerWaalsContact O-CD2 3.32Å; Y494-F498 WeakPolarHBondContact O-CD2 3.27Å; Y494-F498 PolarHBondContact O-N 2.94Å; V496-F498 PolarHBondContact O-N 3.43Å; F498-A500 PolarHBondContact O-N 2.84Å; F498-F510 WeakPolarHBondContact O-CE1 3.41Å; F498-L511 HydrophobicContact CB-CD2 4.24Å; F498-L511 HydrophobicContact CD1-CD2 3.86Å
499G97Very high95.6Very high46 Ų4646.1 Ų46.147%0.47425%0.248SC..THydrogen-bonded Turntrans747.2-175.500000114.3K495 V496 R497K495-G499 CarbonylContact O-C 3.54Å; K495-G499 WeakPolarHBondContact O-CA 3.48Å; K495-G499 PolarHBondContact O-N 2.85Å; V496-G499 PolarHBondContact O-N 3.34Å; V496-G499 VanDerWaalsContact O-N 3.17Å; R497-G499 VanDerWaalsContact C-N 3.33Å
500A97.1Very high96.2Very high14 Ų1447.2 Ų47.212%0.11625%0.251CS..SBendtrans-156.7166.7-174.100000111.9M480 K495 F498 F510 L511M480-A500 WeakPolarHBondContact CE-O 3.46Å; K495-A500 WeakPolarHBondContact CA-O 3.42Å; K495-A500 PolarHBondContact O-N 3.45Å; F498-A500 PolarHBondContact O-N 2.84Å; A500-F510 HydrophobicContact CB-CB 4.19Å; A500-F510 HydrophobicContact CB-CD1 3.51Å; A500-F510 HydrophobicContact CB-CE1 4.26Å; A500-F510 HydrophobicContact CB-CG 4.14Å; A500-L511 HydrophobicContact CB-CD1 4.39Å; A500-L511 HydrophobicContact CB-CD2 4.07Å; A500-L511 HydrophobicContact CB-CG 3.9Å
501S95.6Very high96.6Very high13 Ų1345.7 Ų45.79%0.09124%0.239CC..  trans-115.6138.7171-173.10000110.9K495 E503 G507 K508K495-S501 WeakPolarHBondContact CD-OG 3.43Å; S501-E503 PolarHBondContact O-N 2.89Å; S501-E503 VanDerWaalsContact OG-CB 3.3Å; S501-E503 WeakPolarHBondContact OG-CB 3.41Å; S501-E503 WeakPolarHBondContact OG-CG 3.06Å; S501-E503 PolarHBondContact OG-N 2.66Å; S501-E503 PolarHBondContact OG-OE2 3.26Å; S501-E503 VanDerWaalsContact OG-OE2 3.05Å; S501-G507 CarbonylContact O-C 3.56Å; S501-G507 VanDerWaalsContact O-C 3.3Å; S501-G507 WeakPolarHBondContact O-CA 3.38Å; S501-K508 PolarHBondContact O-N 2.91Å
502A95.7Very high96.9Very high4 Ų449 Ų493%0.03325%0.251CS..THydrogen-bonded Turntrans-76.1-1.4168.200000113.3M480 Q481 K508 L511M480-A502 HydrophobicContact CB-CB 3.68Å; M480-A502 HydrophobicContact SD-CB 4.35Å; Q481-A502 HydrophobicContact CG-CB 3.94Å; A502-K508 WeakPolarHBondContact O-CE 3.24Å; A502-L511 HydrophobicContact CB-CD1 4Å
503E94.5Very high97Very high113 Ų11355 Ų5553%0.52828%0.276SS..THydrogen-bonded Turntrans-88.2-17.8179.4-57.5166.2140.800112.6Y491 K495 S501Y491-E503 HydrophobicContact CE1-CG 4.31Å; K495-E503 IonicContact NZ-OE2 3.77Å; K495-E503 PolarHBondContact NZ-OE2 3.47Å; S501-E503 PolarHBondContact O-N 2.89Å; S501-E503 VanDerWaalsContact OG-CB 3.3Å; S501-E503 WeakPolarHBondContact OG-CB 3.41Å; S501-E503 WeakPolarHBondContact OG-CG 3.06Å; S501-E503 PolarHBondContact OG-N 2.66Å; S501-E503 PolarHBondContact OG-OE2 3.26Å; S501-E503 VanDerWaalsContact OG-OE2 3.05Å
504T96.3Very high97.1Very high63 Ų6355.1 Ų55.139%0.38728%0.276SS..SBendtrans-111.8152.4179.267.40000111G507 K508T504-G507 PolarHBondContact O-N 3.41Å; T504-G507 PolarHBondContact OG1-N 3.31Å; T504-G507 VanDerWaalsContact OG1-N 3.16Å; T504-K508 WeakPolarHBondContact O-CG 3.45Å; T504-K508 PolarHBondContact O-N 3.32Å
505E98Very high97.2Very high114 Ų11453.6 Ų53.653%0.53327%0.27SS..Hα-helixtrans-67.8-40.4179.2-68.1-5612200111.6G507 K508 I509E505-G507 VanDerWaalsContact C-N 3.29Å; E505-G507 PolarHBondContact O-N 3.27Å; E505-K508 PolarHBondContact O-N 3.19Å; E505-K508 IonicContact OE1-NZ 2.87Å; E505-K508 PolarHBondContact OE1-NZ 2.9Å; E505-I509 VanDerWaalsContact O-CG1 3.29Å; E505-I509 WeakPolarHBondContact O-CG1 3.13Å; E505-I509 PolarHBondContact O-N 3.39Å
506E98Very high97.3Very high143 Ų14352.3 Ų52.367%0.66826%0.264SS*.Hα-helixtrans-61.1-40.7175.8-61.773-157.900111.4I509 F510E506-I509 PolarHBondContact O-N 3.48Å; E506-F510 PolarHBondContact O-N 3.03Å
507G97.9Very high97.3Very high6 Ų651.3 Ų51.36%0.06226%0.257CS..Hα-helixtrans-69-41.8178.400000112.1S501 T504 E505 I509 F510 L511S501-G507 CarbonylContact O-C 3.56Å; S501-G507 VanDerWaalsContact O-C 3.3Å; S501-G507 WeakPolarHBondContact O-CA 3.38Å; T504-G507 PolarHBondContact O-N 3.41Å; T504-G507 PolarHBondContact OG1-N 3.31Å; T504-G507 VanDerWaalsContact OG1-N 3.16Å; E505-G507 VanDerWaalsContact C-N 3.29Å; E505-G507 PolarHBondContact O-N 3.27Å; G507-I509 VanDerWaalsContact C-N 3.33Å; G507-I509 PolarHBondContact O-N 3.18Å; G507-F510 PolarHBondContact O-N 3.43Å; G507-L511 WeakPolarHBondContact O-CB 3.39Å; G507-L511 WeakPolarHBondContact O-CG 3.27Å; G507-L511 PolarHBondContact O-N 2.89Å
508K98.5Very high97.4Very high58 Ų5854.6 Ų54.625%0.25227%0.27SS..Hα-helixtrans-58.9-42.9171.4-70.8173-165.9167.10112I477 S501 A502 T504 E505 F510 L511 W512I477-K508 HydrophobicContact CD1-CB 3.95Å; I477-K508 HydrophobicContact CD1-CG 4.32Å; I477-K508 HydrophobicContact CG1-CB 4.46Å; S501-K508 PolarHBondContact O-N 2.91Å; A502-K508 WeakPolarHBondContact O-CE 3.24Å; T504-K508 WeakPolarHBondContact O-CG 3.45Å; T504-K508 PolarHBondContact O-N 3.32Å; E505-K508 PolarHBondContact O-N 3.19Å; E505-K508 IonicContact OE1-NZ 2.87Å; E505-K508 PolarHBondContact OE1-NZ 2.9Å; K508-F510 VanDerWaalsContact C-N 3.33Å; K508-F510 PolarHBondContact O-N 3.17Å; K508-L511 PolarHBondContact O-N 3.4Å; K508-W512 WeakPolarHBondContact O-CB 3.43Å; K508-W512 PolarHBondContact O-N 3.08Å
509I98.3Very high97.5Very high118 Ų11856.3 Ų56.361%0.60528%0.278SS*.Hα-helixtrans-59.3-45.7176.4-70.2164.6000110.6E505 E506 G507 K513E505-I509 VanDerWaalsContact O-CG1 3.29Å; E505-I509 WeakPolarHBondContact O-CG1 3.13Å; E505-I509 PolarHBondContact O-N 3.39Å; E506-I509 PolarHBondContact O-N 3.48Å; G507-I509 VanDerWaalsContact C-N 3.33Å; G507-I509 PolarHBondContact O-N 3.18Å; I509-K513 WeakPolarHBondContact O-CB 3.22Å; I509-K513 PolarHBondContact O-N 2.91Å
510F98Very high97.5Very high70 Ų7054.2 Ų54.231%0.30726%0.256SS..Hα-helixtrans-61.6-51.5176.7176.9-89.7000111.8F498 A500 E506 G507 K508 W512 K513 V514F498-F510 WeakPolarHBondContact O-CE1 3.41Å; A500-F510 HydrophobicContact CB-CB 4.19Å; A500-F510 HydrophobicContact CB-CD1 3.51Å; A500-F510 HydrophobicContact CB-CE1 4.26Å; A500-F510 HydrophobicContact CB-CG 4.14Å; E506-F510 PolarHBondContact O-N 3.03Å; G507-F510 PolarHBondContact O-N 3.43Å; K508-F510 VanDerWaalsContact C-N 3.33Å; K508-F510 PolarHBondContact O-N 3.17Å; F510-W512 PolarHBondContact O-N 2.76Å; F510-K513 WeakPolarHBondContact O-CB 3.29Å; F510-K513 PolarHBondContact O-N 3.1Å; F510-K513 VanDerWaalsContact O-N 3.15Å; F510-V514 HydrophobicContact CE1-CG2 4.49Å; F510-V514 PolarHBondContact O-N 2.79Å
511L98.2Very high97.5Very high0 Ų057.2 Ų57.20%028%0.276CS..Hα-helixtrans-58.8-47.6-178.5-68.4166.2000111.1L476 I477 M480 F498 A500 A502 G507 K508 K513 V514 S515L476-L511 HydrophobicContact CB-CB 4.08Å; L476-L511 HydrophobicContact CB-CD2 3.89Å; L476-L511 HydrophobicContact CD1-CD2 4.4Å; I477-L511 HydrophobicContact CG1-CB 3.82Å; I477-L511 HydrophobicContact CG1-CD1 4.43Å; M480-L511 HydrophobicContact CG-CD1 4.4Å; M480-L511 HydrophobicContact SD-CD1 3.49Å; M480-L511 WeakPolarHBondContact SD-CD1 3.25Å; M480-L511 HydrophobicContact SD-CD2 3.77Å; M480-L511 HydrophobicContact SD-CG 4.28Å; F498-L511 HydrophobicContact CB-CD2 4.24Å; F498-L511 HydrophobicContact CD1-CD2 3.86Å; A500-L511 HydrophobicContact CB-CD1 4.39Å; A500-L511 HydrophobicContact CB-CD2 4.07Å; A500-L511 HydrophobicContact CB-CG 3.9Å; A502-L511 HydrophobicContact CB-CD1 4Å; G507-L511 WeakPolarHBondContact O-CB 3.39Å; G507-L511 WeakPolarHBondContact O-CG 3.27Å; G507-L511 PolarHBondContact O-N 2.89Å; K508-L511 PolarHBondContact O-N 3.4Å; L511-K513 VanDerWaalsContact C-N 3.33Å; L511-K513 PolarHBondContact O-N 2.69Å; L511-V514 WeakPolarHBondContact O-CG2 3.37Å; L511-V514 PolarHBondContact O-N 2.96Å; L511-S515 PolarHBondContact O-N 3.39Å; L511-S515 PolarHBondContact O-OG 2.78Å
512W98Very high97.6Very high101 Ų10159.1 Ų59.138%0.38329%0.285SS..Hα-helixtrans-61.7-39.5176.9-177.6-121000112.7I477 K508 F510 V514 S515 L517 R518I477-W512 HydrophobicContact CD1-CB 3.92Å; K508-W512 WeakPolarHBondContact O-CB 3.43Å; K508-W512 PolarHBondContact O-N 3.08Å; F510-W512 PolarHBondContact O-N 2.76Å; W512-V514 PolarHBondContact O-N 3.4Å; W512-S515 WeakPolarHBondContact O-CB 3.23Å; W512-S515 PolarHBondContact O-N 2.79Å; W512-L517 HydrophobicContact CH2-CB 4.43Å; W512-L517 HydrophobicContact CH2-CD2 4.31Å; W512-L517 HydrophobicContact CH2-CG 4.14Å; W512-L517 HydrophobicContact CZ3-CB 4.27Å; W512-L517 HydrophobicContact CZ3-CD2 4.14Å; W512-L517 HydrophobicContact CZ3-CG 4.26Å; W512-R518 HydrophobicContact CD2-CB 4.2Å; W512-R518 HydrophobicContact CD2-CG 4.34Å; W512-R518 HydrophobicContact CH2-CB 4.08Å; W512-R518 HydrophobicContact CZ2-CB 3.7Å; W512-R518 HydrophobicContact CZ2-CG 3.73Å; W512-R518 HydrophobicContact CZ3-CB 4.48Å; W512-R518 WeakPolarHBondContact O-CD 3.38Å
513K97.3Very high97.7Very high132 Ų13259 Ų5957%0.57428%0.284SS*.Hα-helixtrans-56.5-35.7179.7178.8-173.9172.8-170.80112Y459 I509 F510 L511 R518Y459-K513 PolarHBondContact OH-O 2.66Å; I509-K513 WeakPolarHBondContact O-CB 3.22Å; I509-K513 PolarHBondContact O-N 2.91Å; F510-K513 WeakPolarHBondContact O-CB 3.29Å; F510-K513 PolarHBondContact O-N 3.1Å; F510-K513 VanDerWaalsContact O-N 3.15Å; L511-K513 VanDerWaalsContact C-N 3.33Å; L511-K513 PolarHBondContact O-N 2.69Å; K513-R518 PolarHBondContact O-NE 2.9Å
514V97Very high97.8Very high15 Ų1563 Ų639%0.09130%0.295CS..Hα-helixtrans-99.8-4.8-178.9-60.40000113.9Y455 L476 F510 L511 W512 P516Y455-V514 WeakPolarHBondContact CD2-O 3.35Å; Y455-V514 WeakPolarHBondContact CE2-O 3.2Å; L476-V514 HydrophobicContact CD1-CG2 3.64Å; F510-V514 HydrophobicContact CE1-CG2 4.49Å; F510-V514 PolarHBondContact O-N 2.79Å; L511-V514 WeakPolarHBondContact O-CG2 3.37Å; L511-V514 PolarHBondContact O-N 2.96Å; W512-V514 PolarHBondContact O-N 3.4Å; V514-P516 WeakPolarHBondContact O-CD 3.46Å
515S98.5Very high97.8Very high0 Ų062.4 Ų62.40%029%0.286CS..  trans-63.3127.9174.1-71.20000111.7Y459 S474 D475 L476 L511 W512 L517 R518Y459-S515 PolarHBondContact OH-O 2.73Å; S474-S515 WeakPolarHBondContact O-CB 3.41Å; D475-S515 PolarHBondContact OD1-OG 2.78Å; L476-S515 PolarHBondContact N-OG 3.48Å; L511-S515 PolarHBondContact O-N 3.39Å; L511-S515 PolarHBondContact O-OG 2.78Å; W512-S515 WeakPolarHBondContact O-CB 3.23Å; W512-S515 PolarHBondContact O-N 2.79Å; S515-L517 PolarHBondContact O-N 2.78Å; S515-R518 WeakPolarHBondContact O-CB 3.11Å; S515-R518 PolarHBondContact O-N 3.33Å
516P98.5Very high97.8Very high0 Ų058.9 Ų58.90%027%0.273CS..G310 helixtrans-55.6-37171.5-28.534.3000113.6F451 L454 Y455 S474 V514 R518 Q519 A520F451-P516 HydrophobicContact CD2-CG 3.84Å; F451-P516 VanDerWaalsContact CE2-CD 3.47Å; F451-P516 HydrophobicContact CE2-CG 3.91Å; L454-P516 HydrophobicContact CB-CB 3.6Å; L454-P516 HydrophobicContact CB-CG 3.88Å; Y455-P516 HydrophobicContact CD2-CG 4.4Å; S474-P516 VanDerWaalsContact O-CD 3.27Å; S474-P516 WeakPolarHBondContact O-CD 3.49Å; V514-P516 WeakPolarHBondContact O-CD 3.46Å; P516-R518 PolarHBondContact O-N 2.87Å; P516-R518 VanDerWaalsContact O-N 3.13Å; P516-Q519 CarbonylContact O-C 3.53Å; P516-Q519 PolarHBondContact O-N 3.1Å; P516-A520 PolarHBondContact O-N 2.9Å
517L98.3Very high97.8Very high28 Ų2852.1 Ų52.115%0.14724%0.242CC..G310 helixtrans-54.2-35.4179.9-178.460.7000112.5S474 D475 W512 S515 Q519 A520 A545 M546 A549S474-L517 VanDerWaalsContact O-CB 3.23Å; S474-L517 WeakPolarHBondContact O-CB 3.32Å; S474-L517 PolarHBondContact O-N 2.94Å; D475-L517 HydrophobicContact CB-CD2 3.97Å; W512-L517 HydrophobicContact CH2-CB 4.43Å; W512-L517 HydrophobicContact CH2-CD2 4.31Å; W512-L517 HydrophobicContact CH2-CG 4.14Å; W512-L517 HydrophobicContact CZ3-CB 4.27Å; W512-L517 HydrophobicContact CZ3-CD2 4.14Å; W512-L517 HydrophobicContact CZ3-CG 4.26Å; S515-L517 PolarHBondContact O-N 2.78Å; L517-Q519 PolarHBondContact O-N 3.23Å; L517-A520 WeakPolarHBondContact O-CB 3.38Å; L517-A520 PolarHBondContact O-N 2.87Å; L517-A545 HydrophobicContact CD1-CB 4.37Å; L517-A545 WeakPolarHBondContact CD1-O 2.94Å; L517-A545 HydrophobicContact CD2-CB 3.94Å; L517-M546 HydrophobicContact CB-SD 4.49Å; L517-M546 HydrophobicContact CD1-CB 4.38Å; L517-M546 HydrophobicContact CD1-SD 4.03Å; L517-A549 HydrophobicContact CD1-CB 3.88Å
518R98.1Very high97.8Very high100 Ų10051.9 Ų51.938%0.37724%0.239SC..G310 helixtrans-60.8-31.4179.1-170.5178.584.999.51113.2Y459 W512 K513 S515 P516Y459-R518 PolarHBondContact OH-NE 2.95Å; W512-R518 HydrophobicContact CD2-CB 4.2Å; W512-R518 HydrophobicContact CD2-CG 4.34Å; W512-R518 HydrophobicContact CH2-CB 4.08Å; W512-R518 HydrophobicContact CZ2-CB 3.7Å; W512-R518 HydrophobicContact CZ2-CG 3.73Å; W512-R518 HydrophobicContact CZ3-CB 4.48Å; W512-R518 WeakPolarHBondContact O-CD 3.38Å; K513-R518 PolarHBondContact O-NE 2.9Å; S515-R518 WeakPolarHBondContact O-CB 3.11Å; S515-R518 PolarHBondContact O-N 3.33Å; P516-R518 PolarHBondContact O-N 2.87Å; P516-R518 VanDerWaalsContact O-N 3.13Å
519Q97.9Very high97.8Very high44 Ų4449.1 Ų49.121%0.20623%0.227CC..G310 helixtrans-11422.2-177.2-65-66.2-14.200112.1A458 Y459 P516 L517 S521 N522A458-Q519 HydrophobicContact CB-CB 3.96Å; Y459-Q519 HydrophobicContact CD1-CG 4.23Å; Y459-Q519 HydrophobicContact CD2-CB 4.28Å; Y459-Q519 HydrophobicContact CD2-CG 4.33Å; Y459-Q519 HydrophobicContact CE1-CG 3.58Å; Y459-Q519 HydrophobicContact CE2-CB 3.85Å; Y459-Q519 HydrophobicContact CE2-CG 3.69Å; Y459-Q519 VanDerWaalsContact OH-CG 3.29Å; Y459-Q519 WeakPolarHBondContact OH-CG 3.38Å; P516-Q519 CarbonylContact O-C 3.53Å; P516-Q519 PolarHBondContact O-N 3.1Å; L517-Q519 PolarHBondContact O-N 3.23Å; Q519-S521 PolarHBondContact O-N 2.98Å; Q519-S521 VanDerWaalsContact O-N 3.09Å; Q519-N522 WeakPolarHBondContact O-CB 3.41Å; Q519-N522 PolarHBondContact O-N 3.14Å; Q519-N522 PolarHBondContact OE1-ND2 2.98Å
520A97.9Very high97.8Very high3 Ų343.5 Ų43.53%0.02520%0.199CC..G310 helixtrans-54.4-32.5-17900000113.2P516 L517 N522 V523 M546 A549P516-A520 PolarHBondContact O-N 2.9Å; L517-A520 WeakPolarHBondContact O-CB 3.38Å; L517-A520 PolarHBondContact O-N 2.87Å; A520-N522 PolarHBondContact O-N 3.07Å; A520-V523 WeakPolarHBondContact O-CB 3.44Å; A520-V523 WeakPolarHBondContact O-CG2 3.3Å; A520-V523 PolarHBondContact O-N 3.05Å; A520-M546 HydrophobicContact CB-CE 3.82Å; A520-M546 HydrophobicContact CB-SD 3.79Å; A520-A549 HydrophobicContact CB-CB 3.57Å
521S97.2Very high97.8Very high76 Ų7640.2 Ų40.253%0.53118%0.184SC..G310 helixtrans-65.5-15.8176.9560000114.9Q519Q519-S521 PolarHBondContact O-N 2.98Å; Q519-S521 VanDerWaalsContact O-N 3.09Å
522N97.8Very high97.8Very high53 Ų5340.2 Ų40.228%0.28318%0.184SC..G310 helixtrans-85.4-13.3174.4-64.7-20.1000112.7A458 Q519 A520 R524A458-N522 WeakPolarHBondContact O-CB 3.47Å; A458-N522 PolarHBondContact O-ND2 3.17Å; Q519-N522 WeakPolarHBondContact O-CB 3.41Å; Q519-N522 PolarHBondContact O-N 3.14Å; Q519-N522 PolarHBondContact OE1-ND2 2.98Å; A520-N522 PolarHBondContact O-N 3.07Å; N522-R524 WeakPolarHBondContact O-CG 3.18Å; N522-R524 PolarHBondContact O-N 2.89Å
523V98Very high97.6Very high1 Ų139.6 Ų39.61%0.00619%0.188CC..  trans-70.5103.1177.7-177.40000108.7L457 A458 A520 L527 M546 L550 T555L457-V523 HydrophobicContact CB-CG1 4.11Å; L457-V523 HydrophobicContact CB-CG2 4.3Å; L457-V523 HydrophobicContact CD1-CG1 4.47Å; A458-V523 HydrophobicContact CB-CG2 3.86Å; A520-V523 WeakPolarHBondContact O-CB 3.44Å; A520-V523 WeakPolarHBondContact O-CG2 3.3Å; A520-V523 PolarHBondContact O-N 3.05Å; V523-L527 HydrophobicContact CG1-CD2 4.32Å; V523-M546 HydrophobicContact CG2-CE 4.03Å; V523-L550 HydrophobicContact CB-CD2 3.68Å; V523-L550 HydrophobicContact CG1-CD2 3.9Å; V523-L550 HydrophobicContact CG2-CD2 4.12Å; V523-T555 HydrophobicContact CB-CG2 4.43Å; V523-T555 HydrophobicContact CG1-CG2 3.94Å; V523-T555 WeakPolarHBondContact O-CG2 3.17Å; V523-T555 PolarHBondContact O-OG1 3.31Å
524R95.1Very high97.3Very high199 Ų19938 Ų3875%0.75118%0.183SC*.  trans-110.3-14.6-177.9-66.3173-172.1-144.22113.7N522N522-R524 WeakPolarHBondContact O-CG 3.18Å; N522-R524 PolarHBondContact O-N 2.89Å
525K97.1Very high97.1Very high49 Ų4938 Ų3821%0.21318%0.183CC..SBendtrans-88.2149.4-177.6-60-67.6-171.1171.40110.3L457 P461 Y464 L527L457-K525 HydrophobicContact CD2-CB 4.19Å; P461-K525 VanDerWaalsContact O-CE 3.28Å; P461-K525 WeakPolarHBondContact O-CE 3.42Å; P461-K525 WeakPolarHBondContact O-CG 3.34Å; Y464-K525 WeakPolarHBondContact O-CD 3.28Å; Y464-K525 VanDerWaalsContact O-CE 3.25Å; Y464-K525 WeakPolarHBondContact O-CE 3.49Å; Y464-K525 VanDerWaalsContact O-CG 3.3Å; Y464-K525 WeakPolarHBondContact O-CG 3.11Å; K525-L527 PolarHBondContact O-N 3.48Å
526P97.5Very high96.6Very high40 Ų4043 Ų4326%0.2621%0.21SC..  trans-50.8134.6172.7-29.135.7000112.9Q465 C466 G467 N556 L585Q465-P526 WeakPolarHBondContact O-CD 3.41Å; C466-P526 CarbonylContact C-O 3.56Å; C466-P526 WeakPolarHBondContact CA-O 3.38Å; C466-P526 HydrophobicContact CB-CB 4.14Å; C466-P526 VanDerWaalsContact CB-O 3.28Å; C466-P526 WeakPolarHBondContact CB-O 3.36Å; G467-P526 PolarHBondContact N-O 3.06Å; P526-N556 WeakPolarHBondContact CA-O 3.47Å; P526-L585 HydrophobicContact CB-CD1 3.7Å
527L98.6Very high96.2Very high1 Ų148 Ų481%0.00523%0.229CC..EExtended strand (participates in β ladder)trans-134.3141.8-177.2173.160.1000110.8L454 L457 G467 A469 V523 K525 I529 L550 N556 F557 T558L454-L527 HydrophobicContact CD2-CD1 4.24Å; L454-L527 HydrophobicContact CD2-CD2 3.78Å; L457-L527 HydrophobicContact CD1-CB 4.33Å; L457-L527 HydrophobicContact CD1-CD1 3.86Å; L457-L527 HydrophobicContact CD1-CD2 4.49Å; L457-L527 HydrophobicContact CD1-CG 4.44Å; G467-L527 CarbonylContact O-C 3.48Å; G467-L527 WeakPolarHBondContact O-CA 3.44Å; G467-L527 WeakPolarHBondContact O-CD1 3.48Å; A469-L527 HydrophobicContact CB-CD1 4.26Å; V523-L527 HydrophobicContact CG1-CD2 4.32Å; K525-L527 PolarHBondContact O-N 3.48Å; L527-I529 HydrophobicContact CD1-CG1 4.26Å; L527-I529 HydrophobicContact CD2-CD1 3.81Å; L527-I529 HydrophobicContact CD2-CG1 3.74Å; L527-I529 HydrophobicContact CG-CD1 4.38Å; L527-I529 HydrophobicContact CG-CG1 3.77Å; L527-L550 HydrophobicContact CD2-CD1 3.76Å; L527-N556 PolarHBondContact N-O 2.65Å; L527-F557 HydrophobicContact CB-CB 4Å; L527-F557 CarbonylContact O-C 3.5Å; L527-F557 WeakPolarHBondContact O-CA 3.3Å; L527-F557 VanDerWaalsContact O-CB 3.31Å; L527-F557 WeakPolarHBondContact O-CB 3.49Å; L527-T558 PolarHBondContact O-N 3.36Å
528L98.6Very high96Very high1 Ų147 Ų471%0.00522%0.223CC..EExtended strand (participates in β ladder)trans-110.7125.1162.3-172.8163.6000108.1G467 V468 A469 A530 T558 M560 Y578 M581 I582 L585G467-L528 PolarHBondContact O-N 2.97Å; V468-L528 CarbonylContact C-O 3.21Å; V468-L528 WeakPolarHBondContact CA-O 3.5Å; V468-L528 HydrophobicContact CG1-CD2 4.17Å; V468-L528 HydrophobicContact CG2-CB 4.34Å; A469-L528 PolarHBondContact N-O 2.8Å; L528-A530 HydrophobicContact CD2-CB 3.96Å; L528-T558 HydrophobicContact CG-CG2 4.38Å; L528-M560 HydrophobicContact CD1-SD 3.9Å; L528-M560 HydrophobicContact CD2-SD 3.95Å; L528-M560 HydrophobicContact CG-SD 4.09Å; L528-Y578 HydrophobicContact CD2-CD2 4.29Å; L528-Y578 HydrophobicContact CD2-CE2 3.79Å; L528-M581 HydrophobicContact CD1-CB 3.68Å; L528-I582 HydrophobicContact CD1-CG1 4.34Å; L528-L585 HydrophobicContact CB-CD2 3.9Å
529I98.3Very high95.8Very high1 Ų143.3 Ų43.31%0.00521%0.213CC..EExtended strand (participates in β ladder)trans-109.4126.5171.2-56178.4000108.3A469 L527 T543 M546 L550 F557 T558 M560A469-I529 WeakPolarHBondContact O-CA 3.46Å; L527-I529 HydrophobicContact CD1-CG1 4.26Å; L527-I529 HydrophobicContact CD2-CD1 3.81Å; L527-I529 HydrophobicContact CD2-CG1 3.74Å; L527-I529 HydrophobicContact CG-CD1 4.38Å; L527-I529 HydrophobicContact CG-CG1 3.77Å; I529-T543 HydrophobicContact CG2-CG2 3.49Å; I529-T543 VanDerWaalsContact CG2-CG2 3.49Å; I529-M546 HydrophobicContact CD1-CG 4.08Å; I529-L550 HydrophobicContact CD1-CD1 3.57Å; I529-F557 HydrophobicContact CD1-CD2 4.36Å; I529-T558 PolarHBondContact N-O 2.97Å; I529-M560 PolarHBondContact O-N 2.75Å
530A98.2Very high95.6Very high0 Ų042.4 Ų42.40%021%0.212CC..EExtended strand (participates in β ladder)trans-122.6143.217600000111.5A469 E470 C471 L528 M560 F562 Y578A469-A530 PolarHBondContact O-N 3.17Å; E470-A530 CarbonylContact C-O 3.51Å; E470-A530 WeakPolarHBondContact CA-O 3.47Å; C471-A530 PolarHBondContact N-O 2.89Å; L528-A530 HydrophobicContact CD2-CB 3.96Å; A530-M560 CarbonylContact C-O 3.56Å; A530-M560 WeakPolarHBondContact CA-O 3.35Å; A530-M560 HydrophobicContact CB-CB 4.23Å; A530-F562 HydrophobicContact CB-CE2 4.41Å; A530-Y578 HydrophobicContact CB-CD2 3.82Å; A530-Y578 HydrophobicContact CB-CE2 3.4Å
531H98.2Very high95.5Very high0 Ų048.5 Ų48.50%024%0.238CC..EExtended strand (participates in β ladder)trans-149.7140.7178.3-14696.1000111.7C471 D535 V538 T543 M560 V561 F562C471-H531 WeakPolarHBondContact CA-ND1 3.43Å; H531-D535 IonicContact CE1-OD2 2.65Å; H531-D535 IonicContact NE2-OD2 3.49Å; H531-D535 PolarHBondContact NE2-OD2 2.96Å; H531-V538 PolarHBondContact CE1-O 3.15Å; H531-V538 PolarHBondContact NE2-O 2.74Å; H531-T543 HydrophobicContact CB-CG2 3.89Å; H531-T543 PolarHBondContact CE1-OG1 3.21Å; H531-T543 WeakPolarHBondContact ND1-CB 3.48Å; H531-T543 PolarHBondContact ND1-OG1 3.16Å; H531-M560 PolarHBondContact N-O 2.85Å; H531-V561 WeakPolarHBondContact O-CA 3.42Å; H531-F562 PolarHBondContact O-N 2.52Å
532G96.9Very high95.4Very high0 Ų045 Ų450%021%0.213CC..EExtended strand (participates in β ladder)trans-90.3124.9167.200000111.1M534 D535 E565 G566G532-M534 PolarHBondContact O-N 2.84Å; G532-M534 VanDerWaalsContact O-N 3.14Å; G532-D535 WeakPolarHBondContact O-CB 3.5Å; G532-D535 PolarHBondContact O-N 3.02Å; G532-E565 CarbonylContact C-O 3.59Å; G532-E565 VanDerWaalsContact CA-O 3.22Å; G532-E565 WeakPolarHBondContact CA-O 3.49Å; G532-G566 WeakPolarHBondContact CA-O 3.49Å
533L94.6Very high95.3Very high88 Ų8842.6 Ų42.646%0.46120%0.2SC..THydrogen-bonded Turntrans-65.9-20-173.4-169.260000113.3D535 V561 F562 P563 E565L533-D535 VanDerWaalsContact C-N 3.32Å; L533-V561 HydrophobicContact CB-CG1 4.14Å; L533-V561 HydrophobicContact CD1-CG1 4.4Å; L533-F562 PolarHBondContact N-O 2.9Å; L533-P563 HydrophobicContact CD2-CB 4.39Å; L533-E565 PolarHBondContact N-O 3.45Å
534M91.4Very high95.3Very high98 Ų9845.5 Ų45.548%0.48322%0.216SC..THydrogen-bonded Turntrans-93.113.6177-56-64.7-72.600112.7Y54 G532 D536 P563 E565Y54-M534 HydrophobicContact CE1-CE 4.26Å; G532-M534 PolarHBondContact O-N 2.84Å; G532-M534 VanDerWaalsContact O-N 3.14Å; M534-D536 PolarHBondContact O-N 3.41Å; M534-P563 WeakPolarHBondContact CG-O 3.35Å; M534-E565 WeakPolarHBondContact CA-O 3.3Å; M534-E565 VanDerWaalsContact CB-O 3.3Å; M534-E565 WeakPolarHBondContact CB-O 3.31Å; M534-E565 PolarHBondContact N-O 2.7Å
535D92.7Very high95.4Very high17 Ų1737.6 Ų37.69%0.09119%0.194CC..  trans-61.6116.2175.6-173-12.7000111.3H531 G532 L533 R537 V538 H567H531-D535 IonicContact CE1-OD2 2.65Å; H531-D535 IonicContact NE2-OD2 3.49Å; H531-D535 PolarHBondContact NE2-OD2 2.96Å; G532-D535 WeakPolarHBondContact O-CB 3.5Å; G532-D535 PolarHBondContact O-N 3.02Å; L533-D535 VanDerWaalsContact C-N 3.32Å; D535-R537 WeakPolarHBondContact OD1-CA 3.28Å; D535-R537 PolarHBondContact OD1-N 2.98Å; D535-V538 PolarHBondContact OD1-N 3.47Å; D535-H567 WeakPolarHBondContact OD1-CB 3.4Å; D535-H567 IonicContact OD1-CG 3.91Å; D535-H567 IonicContact OD1-ND1 3.17Å; D535-H567 PolarHBondContact OD1-ND1 3.3Å; D535-H567 IonicContact OD2-CE1 2.69Å; D535-H567 IonicContact OD2-CG 2.66Å; D535-H567 IonicContact OD2-ND1 2.79Å; D535-H567 PolarHBondContact OD2-ND1 3.2Å
536D87.7Confident95.4Very high105 Ų10535.3 Ų35.356%0.56118%0.184SC*.SBendtrans-93.5-3.5179.667.1-14.6000113.6P484 M534P484-D536 WeakPolarHBondContact CB-O 3.41Å; P484-D536 VanDerWaalsContact CD-O 3.26Å; P484-D536 WeakPolarHBondContact CD-O 3.37Å; P484-D536 WeakPolarHBondContact CG-O 3.28Å; M534-D536 PolarHBondContact O-N 3.41Å
537R89.6Confident95.5Very high104 Ų10433.9 Ų33.939%0.39218%0.175SC..SBendtrans-106.1-43.7-176.9-49.8-170.1-177-144.2-3.4112.7W487 D535 H567W487-R537 HydrophobicContact CH2-CB 4.06Å; W487-R537 HydrophobicContact CH2-CG 4.12Å; W487-R537 HydrophobicContact CZ2-CG 4.16Å; D535-R537 WeakPolarHBondContact OD1-CA 3.28Å; D535-R537 PolarHBondContact OD1-N 2.98Å; R537-H567 HydrophobicContact CG-CB 4.19Å
538V93.8Very high95.4Very high6 Ų639.3 Ų39.34%0.03620%0.2CC..SBendtrans-122.9107.5177.4-177.90000108.2P473 H531 D535 S540P473-V538 HydrophobicContact CG-CG1 4.3Å; P473-V538 HydrophobicContact CG-CG2 3.86Å; H531-V538 PolarHBondContact CE1-O 3.15Å; H531-V538 PolarHBondContact NE2-O 2.74Å; D535-V538 PolarHBondContact OD1-N 3.47Å; V538-S540 PolarHBondContact O-N 3.23Å
539S93.9Very high95.4Very high23 Ų2340.4 Ų40.416%0.16121%0.209CC..  trans-51.2128.5177.2176.30000111E478 S482 K541 A542E478-S539 PolarHBondContact OE1-OG 3.06Å; E478-S539 VanDerWaalsContact OE1-OG 3.05Å; S482-S539 WeakPolarHBondContact OG-CB 3.41Å; S539-K541 PolarHBondContact O-N 3.39Å; S539-K541 WeakPolarHBondContact OG-CB 3.18Å; S539-K541 WeakPolarHBondContact OG-CG 3.45Å; S539-K541 PolarHBondContact OG-N 3.34Å; S539-A542 PolarHBondContact O-N 2.92Å
540S94.5Very high95.4Very high25 Ų2540.3 Ų40.318%0.17521%0.209CC..Hα-helixtrans-56.5-23.117670.60000112.3V538 A542 T543 D544V538-S540 PolarHBondContact O-N 3.23Å; S540-A542 PolarHBondContact O-N 3.33Å; S540-T543 CarbonylContact O-C 3.57Å; S540-T543 WeakPolarHBondContact O-CA 3.45Å; S540-T543 WeakPolarHBondContact O-CB 3.39Å; S540-T543 PolarHBondContact O-N 2.79Å; S540-D544 PolarHBondContact O-N 3.05Å
541K95.6Very high95.3Very high132 Ų13243.4 Ų43.457%0.57423%0.227SC*.Hα-helixtrans-55.2-35.4174.9-62.5178.9-174167.60113.1E478 S539 T543 A545E478-K541 WeakPolarHBondContact OE1-CD 3.31Å; S539-K541 PolarHBondContact O-N 3.39Å; S539-K541 WeakPolarHBondContact OG-CB 3.18Å; S539-K541 WeakPolarHBondContact OG-CG 3.45Å; S539-K541 PolarHBondContact OG-N 3.34Å; K541-T543 VanDerWaalsContact C-N 3.32Å; K541-A545 WeakPolarHBondContact O-CB 3.32Å; K541-A545 PolarHBondContact O-N 2.82Å
542A94.8Very high95.2Very high2 Ų251.1 Ų51.12%0.01726%0.261CS..Hα-helixtrans-64.9-41.3176.600000110.6S474 S539 S540 M546S474-A542 VanDerWaalsContact OG-C 3.25Å; S474-A542 PolarHBondContact OG-O 2.84Å; S539-A542 PolarHBondContact O-N 2.92Å; S540-A542 PolarHBondContact O-N 3.33Å; A542-M546 WeakPolarHBondContact O-CB 3.41Å; A542-M546 PolarHBondContact O-N 3.39Å
543T96.5Very high95.1Very high2 Ų253.3 Ų53.31%0.01228%0.277CS..Hα-helixtrans-69.7-44.9176.9-70.10000111.9I529 H531 S540 K541 A545 M546 A547 Y559I529-T543 HydrophobicContact CG2-CG2 3.49Å; I529-T543 VanDerWaalsContact CG2-CG2 3.49Å; H531-T543 HydrophobicContact CB-CG2 3.89Å; H531-T543 PolarHBondContact CE1-OG1 3.21Å; H531-T543 WeakPolarHBondContact ND1-CB 3.48Å; H531-T543 PolarHBondContact ND1-OG1 3.16Å; S540-T543 CarbonylContact O-C 3.57Å; S540-T543 WeakPolarHBondContact O-CA 3.45Å; S540-T543 WeakPolarHBondContact O-CB 3.39Å; S540-T543 PolarHBondContact O-N 2.79Å; K541-T543 VanDerWaalsContact C-N 3.32Å; T543-A545 PolarHBondContact O-N 3.15Å; T543-M546 PolarHBondContact O-N 2.93Å; T543-A547 WeakPolarHBondContact O-CB 3.44Å; T543-A547 PolarHBondContact O-N 3.29Å; T543-Y559 HydrophobicContact CG2-CE2 3.58Å
544D96.9Very high95.1Very high62 Ų6251.7 Ų51.733%0.33228%0.281SS..Hα-helixtrans-57.7-47.4174.3-69.3-43000111.1S540 M546 A547 E548 Y559S540-D544 PolarHBondContact O-N 3.05Å; D544-M546 VanDerWaalsContact C-N 3.33Å; D544-M546 PolarHBondContact O-N 2.9Å; D544-A547 PolarHBondContact O-N 2.81Å; D544-E548 WeakPolarHBondContact O-CG 3.39Å; D544-E548 PolarHBondContact O-N 3.14Å; D544-Y559 PolarHBondContact OD1-OH 3.18Å
545A97.7Very high95.3Very high34 Ų3447.4 Ų47.428%0.28126%0.26SS..Hα-helixtrans-62.6-38.7178.800000112.5L517 K541 T543 A549L517-A545 HydrophobicContact CD1-CB 4.37Å; L517-A545 WeakPolarHBondContact CD1-O 2.94Å; L517-A545 HydrophobicContact CD2-CB 3.94Å; K541-A545 WeakPolarHBondContact O-CB 3.32Å; K541-A545 PolarHBondContact O-N 2.82Å; T543-A545 PolarHBondContact O-N 3.15Å; A545-A549 WeakPolarHBondContact O-CB 3.07Å; A545-A549 PolarHBondContact O-N 3.21Å; A545-A549 VanDerWaalsContact O-N 3.08Å
546M98.3Very high95.4Very high1 Ų150.7 Ų50.71%0.00528%0.278CS..Hα-helixtrans-65.5-46.5174.3-17165.2-178.400111.2L454 L517 A520 V523 I529 A542 T543 D544 E548 A549 L550L454-M546 HydrophobicContact CD1-CG 4.25Å; L454-M546 HydrophobicContact CD2-CE 4.26Å; L517-M546 HydrophobicContact CB-SD 4.49Å; L517-M546 HydrophobicContact CD1-CB 4.38Å; L517-M546 HydrophobicContact CD1-SD 4.03Å; A520-M546 HydrophobicContact CB-CE 3.82Å; A520-M546 HydrophobicContact CB-SD 3.79Å; V523-M546 HydrophobicContact CG2-CE 4.03Å; I529-M546 HydrophobicContact CD1-CG 4.08Å; A542-M546 WeakPolarHBondContact O-CB 3.41Å; A542-M546 PolarHBondContact O-N 3.39Å; T543-M546 PolarHBondContact O-N 2.93Å; D544-M546 VanDerWaalsContact C-N 3.33Å; D544-M546 PolarHBondContact O-N 2.9Å; M546-E548 VanDerWaalsContact C-N 3.34Å; M546-E548 PolarHBondContact O-N 2.9Å; M546-A549 PolarHBondContact O-N 3.16Å; M546-A549 VanDerWaalsContact O-N 3.17Å; M546-L550 HydrophobicContact CE-CD1 4.31Å; M546-L550 HydrophobicContact CE-CD2 4.1Å; M546-L550 HydrophobicContact CE-CG 4.24Å; M546-L550 HydrophobicContact CG-CD1 4.12Å; M546-L550 HydrophobicContact CG-CG 4.45Å; M546-L550 VanDerWaalsContact O-CG 3.26Å; M546-L550 WeakPolarHBondContact O-CG 3.45Å; M546-L550 PolarHBondContact O-N 3.16Å
547A97.9Very high95.9Very high9 Ų945.7 Ų45.77%0.07425%0.251CS..Hα-helixtrans-58-46.7176.800000111.2T543 D544 A549 L550 V551 F557 Y559T543-A547 WeakPolarHBondContact O-CB 3.44Å; T543-A547 PolarHBondContact O-N 3.29Å; D544-A547 PolarHBondContact O-N 2.81Å; A547-A549 VanDerWaalsContact C-N 3.32Å; A547-A549 PolarHBondContact O-N 2.88Å; A547-L550 PolarHBondContact O-N 3.17Å; A547-V551 WeakPolarHBondContact O-CG2 3.28Å; A547-V551 PolarHBondContact O-N 2.82Å; A547-F557 HydrophobicContact CB-CE2 3.87Å; A547-F557 HydrophobicContact CB-CZ 4.01Å; A547-Y559 HydrophobicContact CB-CD2 3.81Å; A547-Y559 HydrophobicContact CB-CE2 3.76Å; A547-Y559 HydrophobicContact CB-CG 4.5Å
548E97.8Very high96.3Very high116 Ų11641.3 Ų41.354%0.54224%0.236SC..Hα-helixtrans-57.9-41.8175.4-75.2-173.6-164.400113.1D544 M546 K552D544-E548 WeakPolarHBondContact O-CG 3.39Å; D544-E548 PolarHBondContact O-N 3.14Å; M546-E548 VanDerWaalsContact C-N 3.34Å; M546-E548 PolarHBondContact O-N 2.9Å; E548-K552 VanDerWaalsContact O-CG 3.3Å; E548-K552 WeakPolarHBondContact O-CG 3.45Å; E548-K552 PolarHBondContact O-N 3.49Å; E548-K552 VanDerWaalsContact O-N 3.14Å; E548-K552 IonicContact OE2-NZ 2.96Å
549A98Very high96.5Very high23 Ų2341.8 Ų41.819%0.1924%0.237CC..Hα-helixtrans-66.5-39.5178.100000111.9L517 A520 A545 M546 A547 K552 S553L517-A549 HydrophobicContact CD1-CB 3.88Å; A520-A549 HydrophobicContact CB-CB 3.57Å; A545-A549 WeakPolarHBondContact O-CB 3.07Å; A545-A549 PolarHBondContact O-N 3.21Å; A545-A549 VanDerWaalsContact O-N 3.08Å; M546-A549 PolarHBondContact O-N 3.16Å; M546-A549 VanDerWaalsContact O-N 3.17Å; A547-A549 VanDerWaalsContact C-N 3.32Å; A547-A549 PolarHBondContact O-N 2.88Å; A549-K552 PolarHBondContact O-N 2.8Å; A549-S553 PolarHBondContact O-N 2.94Å; A549-S553 VanDerWaalsContact O-N 3.09Å; A549-S553 PolarHBondContact O-OG 2.86Å
550L98Very high96.6Very high0 Ų040.7 Ų40.70%023%0.229CC..Hα-helixtrans-67.7-37176.6-68.3173.5000112.9V523 L527 I529 M546 A547 K552 S553 G554 T555 F557V523-L550 HydrophobicContact CB-CD2 3.68Å; V523-L550 HydrophobicContact CG1-CD2 3.9Å; V523-L550 HydrophobicContact CG2-CD2 4.12Å; L527-L550 HydrophobicContact CD2-CD1 3.76Å; I529-L550 HydrophobicContact CD1-CD1 3.57Å; M546-L550 HydrophobicContact CE-CD1 4.31Å; M546-L550 HydrophobicContact CE-CD2 4.1Å; M546-L550 HydrophobicContact CE-CG 4.24Å; M546-L550 HydrophobicContact CG-CD1 4.12Å; M546-L550 HydrophobicContact CG-CG 4.45Å; M546-L550 VanDerWaalsContact O-CG 3.26Å; M546-L550 WeakPolarHBondContact O-CG 3.45Å; M546-L550 PolarHBondContact O-N 3.16Å; A547-L550 PolarHBondContact O-N 3.17Å; L550-K552 VanDerWaalsContact C-N 3.33Å; L550-S553 WeakPolarHBondContact CA-OG 3.47Å; L550-S553 PolarHBondContact O-N 3.33Å; L550-S553 PolarHBondContact O-OG 3.43Å; L550-G554 PolarHBondContact O-N 2.91Å; L550-G554 VanDerWaalsContact O-N 3.12Å; L550-T555 HydrophobicContact CD2-CG2 3.99Å; L550-T555 PolarHBondContact O-N 2.84Å; L550-F557 HydrophobicContact CB-CD1 3.77Å; L550-F557 HydrophobicContact CB-CE1 3.63Å; L550-F557 HydrophobicContact CB-CG 4.39Å; L550-F557 HydrophobicContact CB-CZ 4.14Å; L550-F557 HydrophobicContact CD1-CD1 4.29Å; L550-F557 HydrophobicContact CD1-CD2 4.19Å; L550-F557 HydrophobicContact CD1-CG 4.09Å
551V97.2Very high96.8Very high64 Ų6440 Ų4039%0.38822%0.224SC..Hα-helixtrans-60.9-45.3171.7172.40000110.3A547 S553 G554 F557 Y611A547-V551 WeakPolarHBondContact O-CG2 3.28Å; A547-V551 PolarHBondContact O-N 2.82Å; V551-S553 VanDerWaalsContact C-N 3.29Å; V551-S553 PolarHBondContact O-N 3.42Å; V551-G554 PolarHBondContact O-N 2.88Å; V551-G554 VanDerWaalsContact O-N 3.11Å; V551-F557 HydrophobicContact CG2-CE1 3.79Å; V551-F557 HydrophobicContact CG2-CZ 3.8Å; V551-Y611 HydrophobicContact CG1-CE1 4.36Å; V551-Y611 HydrophobicContact CG2-CD1 3.62Å; V551-Y611 HydrophobicContact CG2-CD2 4.44Å; V551-Y611 HydrophobicContact CG2-CE1 3.42Å; V551-Y611 VanDerWaalsContact CG2-CE1 3.42Å; V551-Y611 HydrophobicContact CG2-CE2 4.29Å; V551-Y611 HydrophobicContact CG2-CG 4.13Å
552K96.2Very high96.8Very high162 Ų16233.8 Ų33.870%0.70420%0.197SC*.Hα-helixtrans-63.4-33.3179.1-70.9165.5-170.2160.70112.5E548 A549 L550 G554E548-K552 VanDerWaalsContact O-CG 3.3Å; E548-K552 WeakPolarHBondContact O-CG 3.45Å; E548-K552 PolarHBondContact O-N 3.49Å; E548-K552 VanDerWaalsContact O-N 3.14Å; E548-K552 IonicContact OE2-NZ 2.96Å; A549-K552 PolarHBondContact O-N 2.8Å; L550-K552 VanDerWaalsContact C-N 3.33Å; K552-G554 VanDerWaalsContact C-N 3.34Å
553S94.4Very high96.8Very high47 Ų4735 Ų3533%0.32921%0.205SC..Hα-helixtrans-83.2-6.8175.656.70000114.4A549 L550 V551 T555A549-S553 PolarHBondContact O-N 2.94Å; A549-S553 VanDerWaalsContact O-N 3.09Å; A549-S553 PolarHBondContact O-OG 2.86Å; L550-S553 WeakPolarHBondContact CA-OG 3.47Å; L550-S553 PolarHBondContact O-N 3.33Å; L550-S553 PolarHBondContact O-OG 3.43Å; V551-S553 VanDerWaalsContact C-N 3.29Å; V551-S553 PolarHBondContact O-N 3.42Å; S553-T555 VanDerWaalsContact C-N 3.29Å; S553-T555 PolarHBondContact OG-OG1 3.06Å
554G94.4Very high96.5Very high53 Ų5339.6 Ų39.655%0.54623%0.229SC..THydrogen-bonded Turntrans70.625.1-177.800000113.5L550 V551 K552L550-G554 PolarHBondContact O-N 2.91Å; L550-G554 VanDerWaalsContact O-N 3.12Å; V551-G554 PolarHBondContact O-N 2.88Å; V551-G554 VanDerWaalsContact O-N 3.11Å; K552-G554 VanDerWaalsContact C-N 3.34Å
555T95Very high96.3Very high9 Ų937 Ų376%0.05522%0.215CC..  trans-68.4144.2-179.9-57.20000110.8V523 L550 S553 F557V523-T555 HydrophobicContact CB-CG2 4.43Å; V523-T555 HydrophobicContact CG1-CG2 3.94Å; V523-T555 WeakPolarHBondContact O-CG2 3.17Å; V523-T555 PolarHBondContact O-OG1 3.31Å; L550-T555 HydrophobicContact CD2-CG2 3.99Å; L550-T555 PolarHBondContact O-N 2.84Å; S553-T555 VanDerWaalsContact C-N 3.29Å; S553-T555 PolarHBondContact OG-OG1 3.06Å; T555-F557 PolarHBondContact O-N 2.75Å
556N95Very high96Very high85 Ų8536.1 Ų36.146%0.45521%0.209SC..  trans-79.6111.7170.7-176.5-20.2000109.4P526 L527 Y611P526-N556 WeakPolarHBondContact CA-O 3.47Å; L527-N556 PolarHBondContact N-O 2.65Å; N556-Y611 VanDerWaalsContact CA-O 3.27Å; N556-Y611 WeakPolarHBondContact CA-O 3.38Å; N556-Y611 PolarHBondContact OD1-O 2.79Å; N556-Y611 VanDerWaalsContact OD1-O 3.11Å
557F97.8Very high95.8Very high0 Ų037.3 Ų37.30%022%0.215CC..EExtended strand (participates in β ladder)trans-148.9155.717778.4-76.7000112.9L527 I529 A547 L550 V551 T555 Y559 Y611L527-F557 HydrophobicContact CB-CB 4Å; L527-F557 CarbonylContact O-C 3.5Å; L527-F557 WeakPolarHBondContact O-CA 3.3Å; L527-F557 VanDerWaalsContact O-CB 3.31Å; L527-F557 WeakPolarHBondContact O-CB 3.49Å; I529-F557 HydrophobicContact CD1-CD2 4.36Å; A547-F557 HydrophobicContact CB-CE2 3.87Å; A547-F557 HydrophobicContact CB-CZ 4.01Å; L550-F557 HydrophobicContact CB-CD1 3.77Å; L550-F557 HydrophobicContact CB-CE1 3.63Å; L550-F557 HydrophobicContact CB-CG 4.39Å; L550-F557 HydrophobicContact CB-CZ 4.14Å; L550-F557 HydrophobicContact CD1-CD1 4.29Å; L550-F557 HydrophobicContact CD1-CD2 4.19Å; L550-F557 HydrophobicContact CD1-CG 4.09Å; V551-F557 HydrophobicContact CG2-CE1 3.79Å; V551-F557 HydrophobicContact CG2-CZ 3.8Å; T555-F557 PolarHBondContact O-N 2.75Å; F557-Y559 HydrophobicContact CE2-CD2 4.28Å; F557-Y559 HydrophobicContact CE2-CG 4.43Å; F557-Y611 HydrophobicContact CD1-CD2 4.14Å; F557-Y611 HydrophobicContact CD1-CG 4.09Å; F557-Y611 HydrophobicContact CD2-CD2 4.44Å; F557-Y611 VanDerWaalsContact CE1-CB 3.46Å; F557-Y611 HydrophobicContact CE1-CD1 4.29Å; F557-Y611 AromaticContact CE1-CD2 3.5Å; F557-Y611 HydrophobicContact CE1-CD2 3.5Å; F557-Y611 VanDerWaalsContact CE1-CD2 3.5Å; F557-Y611 HydrophobicContact CE1-CE2 4.31Å; F557-Y611 AromaticContact CE1-CG 3.48Å; F557-Y611 HydrophobicContact CE1-CG 3.48Å; F557-Y611 VanDerWaalsContact CE1-CG 3.48Å; F557-Y611 AromaticContact CE2-CD2 3.86Å; F557-Y611 HydrophobicContact CE2-CD2 3.86Å; F557-Y611 HydrophobicContact CE2-CE2 4.29Å; F557-Y611 AromaticContact CZ-CD2 3.32Å; F557-Y611 HydrophobicContact CZ-CD2 3.32Å; F557-Y611 AromaticContact CZ-CE2 3.76Å; F557-Y611 HydrophobicContact CZ-CE2 3.76Å; F557-Y611 AromaticContact CZ-CG 3.82Å; F557-Y611 HydrophobicContact CZ-CG 3.82Å; F557-Y611 PolarHBondContact N-O 2.78Å; F557-Y611 PolarHBondContact O-N 2.82Å
558T98Very high95.4Very high12 Ų1239.6 Ų39.67%0.07423%0.23CC..EExtended strand (participates in β ladder)trans-103.8132.2170.9-56.90000108.9L527 L528 I529 M560 M581 L608 E609 Q610L527-T558 PolarHBondContact O-N 3.36Å; L528-T558 HydrophobicContact CG-CG2 4.38Å; I529-T558 PolarHBondContact N-O 2.97Å; T558-M560 HydrophobicContact CG2-CG 3.96Å; T558-M560 HydrophobicContact CG2-SD 4.3Å; T558-M581 HydrophobicContact CG2-CE 3.96Å; T558-L608 HydrophobicContact CG2-CD1 3.66Å; T558-E609 CarbonylContact C-O 3.58Å; T558-E609 WeakPolarHBondContact CA-O 3.49Å; T558-Q610 HydrophobicContact CG2-CG 4.21Å
559Y98.1Very high95.2Very high16 Ų1634.6 Ų34.66%0.06321%0.206CC..EExtended strand (participates in β ladder)trans-109.7120.3177.5-169.8-120.6000109.5T543 D544 A547 F557 V561 T607 L608 E609T543-Y559 HydrophobicContact CG2-CE2 3.58Å; D544-Y559 PolarHBondContact OD1-OH 3.18Å; A547-Y559 HydrophobicContact CB-CD2 3.81Å; A547-Y559 HydrophobicContact CB-CE2 3.76Å; A547-Y559 HydrophobicContact CB-CG 4.5Å; F557-Y559 HydrophobicContact CE2-CD2 4.28Å; F557-Y559 HydrophobicContact CE2-CG 4.43Å; Y559-V561 HydrophobicContact CD1-CG2 4.21Å; Y559-V561 HydrophobicContact CE1-CG2 3.42Å; Y559-V561 VanDerWaalsContact CE1-CG2 3.42Å; Y559-V561 HydrophobicContact CE2-CG2 4.03Å; Y559-V561 WeakPolarHBondContact OH-CG2 3.44Å; Y559-T607 HydrophobicContact CD1-CG2 4.49Å; Y559-L608 WeakPolarHBondContact O-CA 3.45Å; Y559-E609 PolarHBondContact N-O 2.92Å; Y559-E609 PolarHBondContact O-N 2.83Å
560M97.6Very high94.7Very high0 Ų038.8 Ų38.80%023%0.226CC..EExtended strand (participates in β ladder)trans-126.7112.8-178.4-63.8-176.671.300110.3L528 I529 A530 H531 T558 F562 M581 I606 T607 L608L528-M560 HydrophobicContact CD1-SD 3.9Å; L528-M560 HydrophobicContact CD2-SD 3.95Å; L528-M560 HydrophobicContact CG-SD 4.09Å; I529-M560 PolarHBondContact O-N 2.75Å; A530-M560 CarbonylContact C-O 3.56Å; A530-M560 WeakPolarHBondContact CA-O 3.35Å; A530-M560 HydrophobicContact CB-CB 4.23Å; H531-M560 PolarHBondContact N-O 2.85Å; T558-M560 HydrophobicContact CG2-CG 3.96Å; T558-M560 HydrophobicContact CG2-SD 4.3Å; M560-F562 HydrophobicContact CB-CE2 4.07Å; M560-F562 HydrophobicContact CE-CE2 4.32Å; M560-F562 HydrophobicContact CE-CZ 3.77Å; M560-M581 HydrophobicContact CE-CB 4.08Å; M560-M581 HydrophobicContact CE-CG 3.67Å; M560-M581 HydrophobicContact SD-CB 3.67Å; M560-M581 HydrophobicContact SD-CG 3.75Å; M560-I606 HydrophobicContact CB-CD1 4.32Å; M560-I606 HydrophobicContact CE-CD1 3.55Å; M560-T607 CarbonylContact C-O 3.34Å; M560-T607 VanDerWaalsContact CA-O 3.29Å; M560-T607 WeakPolarHBondContact CA-O 3.08Å; M560-L608 HydrophobicContact CE-CD1 4.43Å; M560-L608 HydrophobicContact CG-CD1 3.58Å; M560-L608 HydrophobicContact SD-CD1 4.18Å
561V97.9Very high94.2Very high12 Ų1244.3 Ų44.37%0.07325%0.252CS..EExtended strand (participates in β ladder)trans-119.5125.1173.7-178.10000110.1H531 L533 Y559 P563 I606 T607H531-V561 WeakPolarHBondContact O-CA 3.42Å; L533-V561 HydrophobicContact CB-CG1 4.14Å; L533-V561 HydrophobicContact CD1-CG1 4.4Å; Y559-V561 HydrophobicContact CD1-CG2 4.21Å; Y559-V561 HydrophobicContact CE1-CG2 3.42Å; Y559-V561 VanDerWaalsContact CE1-CG2 3.42Å; Y559-V561 HydrophobicContact CE2-CG2 4.03Å; Y559-V561 WeakPolarHBondContact OH-CG2 3.44Å; V561-P563 WeakPolarHBondContact O-CD 3.37Å; V561-I606 WeakPolarHBondContact O-CA 2.93Å; V561-I606 WeakPolarHBondContact O-CG1 3.22Å; V561-T607 PolarHBondContact N-O 2.84Å; V561-T607 PolarHBondContact O-N 3.01Å
562F96.2Very high93.9Very high1 Ų148.4 Ų48.40%0.00427%0.267CS..EExtended strand (participates in β ladder)trans-102.9107.5-179.3-62.1-94.3000109.3A530 H531 L533 M560 N564 E565 I569 A577 L604 I606A530-F562 HydrophobicContact CB-CE2 4.41Å; H531-F562 PolarHBondContact O-N 2.52Å; L533-F562 PolarHBondContact N-O 2.9Å; M560-F562 HydrophobicContact CB-CE2 4.07Å; M560-F562 HydrophobicContact CE-CE2 4.32Å; M560-F562 HydrophobicContact CE-CZ 3.77Å; F562-N564 PolarHBondContact O-N 3Å; F562-E565 HydrophobicContact CB-CB 3.73Å; F562-E565 HydrophobicContact CB-CG 3.5Å; F562-E565 VanDerWaalsContact CB-CG 3.5Å; F562-E565 HydrophobicContact CD1-CG 4.47Å; F562-E565 HydrophobicContact CG-CG 4.12Å; F562-E565 PolarHBondContact O-N 3.08Å; F562-I569 HydrophobicContact CB-CD1 4.22Å; F562-I569 HydrophobicContact CD2-CD1 3.46Å; F562-I569 VanDerWaalsContact CD2-CD1 3.46Å; F562-I569 HydrophobicContact CD2-CG1 4.14Å; F562-I569 HydrophobicContact CE1-CG2 4.37Å; F562-I569 HydrophobicContact CE2-CD1 3.97Å; F562-I569 HydrophobicContact CE2-CG1 4.13Å; F562-I569 HydrophobicContact CE2-CG2 4.34Å; F562-I569 HydrophobicContact CG-CD1 3.99Å; F562-I569 HydrophobicContact CZ-CG2 4.25Å; F562-A577 HydrophobicContact CE1-CB 4.49Å; F562-L604 HydrophobicContact CE1-CD2 4.07Å; F562-I606 HydrophobicContact CD1-CD1 3.9Å; F562-I606 HydrophobicContact CD1-CG1 4Å; F562-I606 HydrophobicContact CE1-CD1 3.4Å; F562-I606 HydrophobicContact CE1-CG1 4.03Å; F562-I606 HydrophobicContact CE2-CD1 4.14Å; F562-I606 HydrophobicContact CG-CD1 4.47Å; F562-I606 HydrophobicContact CG-CG1 4.37Å; F562-I606 HydrophobicContact CZ-CD1 3.54Å; F562-I606 HydrophobicContact CZ-CG1 4.42Å
563P93.7Very high93.7Very high26 Ų2645.5 Ų45.517%0.16925%0.251CS..THydrogen-bonded Turntrans-61.6-27.6-172.7-26.938.1000114.9L533 M534 V561 D605L533-P563 HydrophobicContact CD2-CB 4.39Å; M534-P563 WeakPolarHBondContact CG-O 3.35Å; V561-P563 WeakPolarHBondContact O-CD 3.37Å; P563-D605 WeakPolarHBondContact CD-O 3.3Å
564N89.7Confident93.7Very high100 Ų10043.6 Ų43.654%0.53524%0.238SC..THydrogen-bonded Turntrans-105.22.3-174-56.8-51.4000113.7F562F562-N564 PolarHBondContact O-N 3Å
565E93.3Very high93.7Very high8 Ų844.3 Ų44.34%0.03723%0.228CC..  trans-97.8153.5178.9-64.4-74.5-175.800111.5G532 L533 M534 F562 I569 N570 E571 S574G532-E565 CarbonylContact C-O 3.59Å; G532-E565 VanDerWaalsContact CA-O 3.22Å; G532-E565 WeakPolarHBondContact CA-O 3.49Å; L533-E565 PolarHBondContact N-O 3.45Å; M534-E565 WeakPolarHBondContact CA-O 3.3Å; M534-E565 VanDerWaalsContact CB-O 3.3Å; M534-E565 WeakPolarHBondContact CB-O 3.31Å; M534-E565 PolarHBondContact N-O 2.7Å; F562-E565 HydrophobicContact CB-CB 3.73Å; F562-E565 HydrophobicContact CB-CG 3.5Å; F562-E565 VanDerWaalsContact CB-CG 3.5Å; F562-E565 HydrophobicContact CD1-CG 4.47Å; F562-E565 HydrophobicContact CG-CG 4.12Å; F562-E565 PolarHBondContact O-N 3.08Å; E565-I569 HydrophobicContact CB-CD1 3.73Å; E565-I569 HydrophobicContact CG-CD1 3.96Å; E565-I569 HydrophobicContact CG-CG2 4.28Å; E565-N570 PolarHBondContact OE1-N 3.33Å; E565-N570 PolarHBondContact OE2-N 2.85Å; E565-E571 WeakPolarHBondContact OE1-CA 3.31Å; E565-E571 WeakPolarHBondContact OE1-CB 2.95Å; E565-E571 WeakPolarHBondContact OE1-CG 2.83Å; E565-E571 PolarHBondContact OE1-N 3.41Å; E565-S574 WeakPolarHBondContact OE1-CB 3.3Å; E565-S574 PolarHBondContact OE1-OG 2.84Å
566G92.1Very high93.7Very high15 Ų1548.1 Ų48.116%0.15525%0.247CC..  trans-98-141.3176.700000113G532 C568G532-G566 WeakPolarHBondContact CA-O 3.49Å; G566-C568 PolarHBondContact O-N 2.95Å
567H93.8Very high93.7Very high25 Ų2544 Ų4412%0.11623%0.225CC..SBendtrans-67-4.5177.4-164.760.3000114.9S447 D535 R537S447-H567 VanDerWaalsContact CB-NE2 3.27Å; S447-H567 WeakPolarHBondContact CB-NE2 3.22Å; S447-H567 PolarHBondContact OG-CE1 2.7Å; S447-H567 PolarHBondContact OG-NE2 3Å; D535-H567 WeakPolarHBondContact OD1-CB 3.4Å; D535-H567 IonicContact OD1-CG 3.91Å; D535-H567 IonicContact OD1-ND1 3.17Å; D535-H567 PolarHBondContact OD1-ND1 3.3Å; D535-H567 IonicContact OD2-CE1 2.69Å; D535-H567 IonicContact OD2-CG 2.66Å; D535-H567 IonicContact OD2-ND1 2.79Å; D535-H567 PolarHBondContact OD2-ND1 3.2Å; R537-H567 HydrophobicContact CG-CB 4.19Å
568C89.2Confident93.7Very high58 Ų5844.3 Ų44.339%0.39223%0.227SC..SBendtrans-140.9143.2176.8-63.20000108.1E470 G566 N570E470-C568 WeakPolarHBondContact OE1-CA 3.14Å; G566-C568 PolarHBondContact O-N 2.95Å; C568-N570 WeakPolarHBondContact CB-ND2 3.33Å; C568-N570 PolarHBondContact O-N 2.98Å
569I92.8Very high93.6Very high10 Ų1045.3 Ų45.35%0.05123%0.23CC..  trans-84.699.2172.9-50.7-51000109.3E470 F562 E565 S574E470-I569 PolarHBondContact OE1-N 2.83Å; F562-I569 HydrophobicContact CB-CD1 4.22Å; F562-I569 HydrophobicContact CD2-CD1 3.46Å; F562-I569 VanDerWaalsContact CD2-CD1 3.46Å; F562-I569 HydrophobicContact CD2-CG1 4.14Å; F562-I569 HydrophobicContact CE1-CG2 4.37Å; F562-I569 HydrophobicContact CE2-CD1 3.97Å; F562-I569 HydrophobicContact CE2-CG1 4.13Å; F562-I569 HydrophobicContact CE2-CG2 4.34Å; F562-I569 HydrophobicContact CG-CD1 3.99Å; F562-I569 HydrophobicContact CZ-CG2 4.25Å; E565-I569 HydrophobicContact CB-CD1 3.73Å; E565-I569 HydrophobicContact CG-CD1 3.96Å; E565-I569 HydrophobicContact CG-CG2 4.28Å; I569-S574 VanDerWaalsContact CG2-CB 3.45Å
570N88Confident93.5Very high112 Ų11245.1 Ų45.160%0.59923%0.231SC*.  trans-113.3-28.6-169.6-72.5-47.1000114.6E565 C568 E572E565-N570 PolarHBondContact OE1-N 3.33Å; E565-N570 PolarHBondContact OE2-N 2.85Å; C568-N570 WeakPolarHBondContact CB-ND2 3.33Å; C568-N570 PolarHBondContact O-N 2.98Å; N570-E572 PolarHBondContact O-N 3.14Å
571E88.9Confident93.5Very high116 Ų11645.5 Ų45.554%0.54223%0.233SC..SBendtrans-64137.3179.3-64.5-153166.300109.9E565 R573 S574 M575E565-E571 WeakPolarHBondContact OE1-CA 3.31Å; E565-E571 WeakPolarHBondContact OE1-CB 2.95Å; E565-E571 WeakPolarHBondContact OE1-CG 2.83Å; E565-E571 PolarHBondContact OE1-N 3.41Å; E571-R573 VanDerWaalsContact C-N 3.3Å; E571-R573 PolarHBondContact O-N 2.78Å; E571-S574 WeakPolarHBondContact O-CB 3.49Å; E571-S574 PolarHBondContact O-N 3.06Å; E571-M575 WeakPolarHBondContact O-CB 3.3Å; E571-M575 PolarHBondContact O-N 2.88Å
572E89.5Confident93.5Very high150 Ų15045 Ų4570%0.70123%0.23SC*.Hα-helixtrans-52.9-47-172.3-177.1-179173.100112.1N570 M575 L576N570-E572 PolarHBondContact O-N 3.14Å; E572-M575 PolarHBondContact O-N 2.84Å; E572-L576 HydrophobicContact CG-CD1 4.17Å; E572-L576 WeakPolarHBondContact O-CB 3.33Å; E572-L576 VanDerWaalsContact O-CG 3.24Å; E572-L576 WeakPolarHBondContact O-CG 3.32Å; E572-L576 PolarHBondContact O-N 3.15Å
573R92.2Very high93.5Very high101 Ų10145.8 Ų45.838%0.38123%0.234SC..Hα-helixtrans-66.7-39.3179.6-65.7-74.3-85.9-176.90.2112E571 A577 D599 E602 L604E571-R573 VanDerWaalsContact C-N 3.3Å; E571-R573 PolarHBondContact O-N 2.78Å; R573-A577 WeakPolarHBondContact O-CB 3.03Å; R573-A577 PolarHBondContact O-N 2.93Å; R573-D599 IonicContact NH1-OD2 2.75Å; R573-E602 PolarHBondContact NH2-O 3.49Å; R573-L604 HydrophobicContact CB-CD1 3.99Å
574S94.7Very high93.6Very high6 Ų646 Ų464%0.04223%0.233CC..Hα-helixtrans-64.7-43.7175.5-53.40000111.7E565 I569 E571 A577 Y578E565-S574 WeakPolarHBondContact OE1-CB 3.3Å; E565-S574 PolarHBondContact OE1-OG 2.84Å; I569-S574 VanDerWaalsContact CG2-CB 3.45Å; E571-S574 WeakPolarHBondContact O-CB 3.49Å; E571-S574 PolarHBondContact O-N 3.06Å; S574-A577 PolarHBondContact O-N 3.23Å; S574-Y578 VanDerWaalsContact O-CB 3.32Å; S574-Y578 WeakPolarHBondContact O-CB 3.29Å; S574-Y578 PolarHBondContact O-N 3.29Å
575M94.2Very high93.9Very high69 Ų6942 Ų4234%0.3421%0.211SC..Hα-helixtrans-63.8-44.7178.8-173.6-178.5-59.100111.2E571 E572 Y578 F579E571-M575 WeakPolarHBondContact O-CB 3.3Å; E571-M575 PolarHBondContact O-N 2.88Å; E572-M575 PolarHBondContact O-N 2.84Å; M575-Y578 PolarHBondContact O-N 3.39Å; M575-F579 HydrophobicContact CG-CD2 3.74Å; M575-F579 HydrophobicContact CG-CE2 3.79Å; M575-F579 WeakPolarHBondContact O-CD2 3.32Å; M575-F579 PolarHBondContact O-N 2.99Å; M575-F579 HydrophobicContact SD-CE2 4.47Å
576L94.4Very high94.2Very high88 Ų8841.6 Ų41.646%0.46121%0.209SC..Hα-helixtrans-60.4-46.3174.9-72.1171.8000111.6E572 Y578 A580E572-L576 HydrophobicContact CG-CD1 4.17Å; E572-L576 WeakPolarHBondContact O-CB 3.33Å; E572-L576 VanDerWaalsContact O-CG 3.24Å; E572-L576 WeakPolarHBondContact O-CG 3.32Å; E572-L576 PolarHBondContact O-N 3.15Å; L576-Y578 PolarHBondContact O-N 2.96Å; L576-A580 VanDerWaalsContact O-CB 3.23Å; L576-A580 WeakPolarHBondContact O-CB 3.4Å; L576-A580 PolarHBondContact O-N 2.79Å
577A95.9Very high94.3Very high0 Ų041.6 Ų41.60%021%0.208CC..Hα-helixtrans-59.9-45.4175.100000112.5F562 R573 S574 A580 M581 S600 L601 L604F562-A577 HydrophobicContact CE1-CB 4.49Å; R573-A577 WeakPolarHBondContact O-CB 3.03Å; R573-A577 PolarHBondContact O-N 2.93Å; S574-A577 PolarHBondContact O-N 3.23Å; A577-A580 PolarHBondContact O-N 2.83Å; A577-M581 VanDerWaalsContact O-CG 3.31Å; A577-M581 WeakPolarHBondContact O-CG 3.45Å; A577-M581 PolarHBondContact O-N 2.87Å; A577-M581 VanDerWaalsContact O-N 3.11Å; A577-S600 WeakPolarHBondContact CB-O 3.23Å; A577-L601 HydrophobicContact CB-CD2 3.81Å; A577-L604 HydrophobicContact CB-CD2 3.39Å
578Y97.1Very high94.4Very high6 Ų648.1 Ų48.12%0.02423%0.231CC..Hα-helixtrans-60.1-52.2179.3178.9-124.6000111.5V468 L528 A530 S574 M575 L576 A580 M581 I582V468-Y578 HydrophobicContact CG1-CE2 4.18Å; V468-Y578 WeakPolarHBondContact CG1-OH 3.33Å; L528-Y578 HydrophobicContact CD2-CD2 4.29Å; L528-Y578 HydrophobicContact CD2-CE2 3.79Å; A530-Y578 HydrophobicContact CB-CD2 3.82Å; A530-Y578 HydrophobicContact CB-CE2 3.4Å; S574-Y578 VanDerWaalsContact O-CB 3.32Å; S574-Y578 WeakPolarHBondContact O-CB 3.29Å; S574-Y578 PolarHBondContact O-N 3.29Å; M575-Y578 PolarHBondContact O-N 3.39Å; L576-Y578 PolarHBondContact O-N 2.96Å; Y578-A580 PolarHBondContact O-N 2.55Å; Y578-M581 PolarHBondContact O-N 2.97Å; Y578-I582 HydrophobicContact CD1-CD1 3.91Å; Y578-I582 HydrophobicContact CD2-CD1 4.3Å; Y578-I582 HydrophobicContact CE1-CD1 3.5Å; Y578-I582 HydrophobicContact CE2-CD1 3.92Å; Y578-I582 HydrophobicContact CE2-CG1 4.29Å; Y578-I582 HydrophobicContact CG-CD1 4.29Å; Y578-I582 WeakPolarHBondContact O-CG1 3.41Å; Y578-I582 PolarHBondContact O-N 3Å
579F96.7Very high94.7Very high33 Ų3346.8 Ų46.815%0.14522%0.222CC..Hα-helixtrans-68.1-34.8179.1-81.2-67.7000113.2E381 L384 M575 M581 I582 E583E381-F579 HydrophobicContact CB-CE1 4.41Å; E381-F579 HydrophobicContact CB-CZ 4.19Å; E381-F579 HydrophobicContact CG-CE1 3.99Å; E381-F579 HydrophobicContact CG-CZ 4.14Å; L384-F579 HydrophobicContact CD2-CB 3.88Å; L384-F579 HydrophobicContact CD2-CD1 3.54Å; L384-F579 HydrophobicContact CD2-CE1 4.27Å; L384-F579 HydrophobicContact CD2-CG 3.78Å; M575-F579 HydrophobicContact CG-CD2 3.74Å; M575-F579 HydrophobicContact CG-CE2 3.79Å; M575-F579 WeakPolarHBondContact O-CD2 3.32Å; M575-F579 PolarHBondContact O-N 2.99Å; M575-F579 HydrophobicContact SD-CE2 4.47Å; F579-M581 PolarHBondContact O-N 2.86Å; F579-I582 HydrophobicContact CD1-CD1 3.86Å; F579-I582 HydrophobicContact CE1-CD1 4.02Å; F579-I582 PolarHBondContact O-N 2.94Å; F579-E583 WeakPolarHBondContact O-CG 3.39Å; F579-E583 PolarHBondContact O-N 3.2Å
580A96.4Very high94.8Very high11 Ų1146.3 Ų46.39%0.09122%0.22CC..Hα-helixtrans-57.1-42.4172.300000111L576 A577 Y578 E583 Q584 V597L576-A580 VanDerWaalsContact O-CB 3.23Å; L576-A580 WeakPolarHBondContact O-CB 3.4Å; L576-A580 PolarHBondContact O-N 2.79Å; A577-A580 PolarHBondContact O-N 2.83Å; Y578-A580 PolarHBondContact O-N 2.55Å; A580-E583 PolarHBondContact O-N 3.24Å; A580-Q584 WeakPolarHBondContact O-CG 3.17Å; A580-Q584 PolarHBondContact O-N 3.17Å; A580-Q584 VanDerWaalsContact O-N 3.11Å; A580-V597 HydrophobicContact CB-CG1 4.38Å
581M96.7Very high94.8Very high9 Ų947.4 Ų47.44%0.04423%0.226CC..Hα-helixtrans-72.4-34.4178.3-66.5-57.8-60.600113.1L528 T558 M560 A577 Y578 F579 Q584 L585 V597 L601 L608L528-M581 HydrophobicContact CD1-CB 3.68Å; T558-M581 HydrophobicContact CG2-CE 3.96Å; M560-M581 HydrophobicContact CE-CB 4.08Å; M560-M581 HydrophobicContact CE-CG 3.67Å; M560-M581 HydrophobicContact SD-CB 3.67Å; M560-M581 HydrophobicContact SD-CG 3.75Å; A577-M581 VanDerWaalsContact O-CG 3.31Å; A577-M581 WeakPolarHBondContact O-CG 3.45Å; A577-M581 PolarHBondContact O-N 2.87Å; A577-M581 VanDerWaalsContact O-N 3.11Å; Y578-M581 PolarHBondContact O-N 2.97Å; F579-M581 PolarHBondContact O-N 2.86Å; M581-Q584 PolarHBondContact O-N 3.43Å; M581-L585 PolarHBondContact O-N 3.3Å; M581-V597 HydrophobicContact SD-CG2 4.39Å; M581-L601 HydrophobicContact SD-CD1 4.3Å; M581-L608 HydrophobicContact CE-CD1 4.24Å
582I97.4Very high94.6Very high0 Ų042.8 Ų42.80%021%0.209CC..Hα-helixtrans-60.4-48.4170.5-70171.2000110.6L385 M444 V468 L528 Y578 F579 Q584 L585 F586L385-I582 HydrophobicContact CD2-CG2 4.37Å; M444-I582 HydrophobicContact CE-CD1 4.25Å; V468-I582 HydrophobicContact CG1-CD1 4.07Å; V468-I582 HydrophobicContact CG1-CG1 4.02Å; V468-I582 HydrophobicContact CG2-CG1 4.11Å; V468-I582 HydrophobicContact CG2-CG2 4.46Å; L528-I582 HydrophobicContact CD1-CG1 4.34Å; Y578-I582 HydrophobicContact CD1-CD1 3.91Å; Y578-I582 HydrophobicContact CD2-CD1 4.3Å; Y578-I582 HydrophobicContact CE1-CD1 3.5Å; Y578-I582 HydrophobicContact CE2-CD1 3.92Å; Y578-I582 HydrophobicContact CE2-CG1 4.29Å; Y578-I582 HydrophobicContact CG-CD1 4.29Å; Y578-I582 WeakPolarHBondContact O-CG1 3.41Å; Y578-I582 PolarHBondContact O-N 3Å; F579-I582 HydrophobicContact CD1-CD1 3.86Å; F579-I582 HydrophobicContact CE1-CD1 4.02Å; F579-I582 PolarHBondContact O-N 2.94Å; I582-Q584 VanDerWaalsContact C-N 3.29Å; I582-Q584 PolarHBondContact O-N 2.52Å; I582-L585 PolarHBondContact O-N 3.05Å; I582-L585 VanDerWaalsContact O-N 3.13Å; I582-F586 HydrophobicContact CG2-CD2 3.57Å; I582-F586 HydrophobicContact CG2-CE2 3.4Å; I582-F586 HydrophobicContact CG2-CG 4.36Å; I582-F586 HydrophobicContact CG2-CZ 4.06Å; I582-F586 PolarHBondContact O-N 3.01Å
583E96.6Very high94.7Very high19 Ų1938.6 Ų38.69%0.08920%0.197CC..Hα-helixtrans-57.7-43.3177.6-74.3-166.659.300111.4R388 F579 A580 L585 A587 N594 E595R388-E583 HydrophobicContact CG-CG 4.4Å; R388-E583 IonicContact CZ-OE1 3.96Å; R388-E583 IonicContact CZ-OE2 3.36Å; R388-E583 IonicContact NE-OE1 3.97Å; R388-E583 PolarHBondContact NE-OE1 3.43Å; R388-E583 IonicContact NE-OE2 3.38Å; R388-E583 IonicContact NH2-OE1 2.76Å; R388-E583 PolarHBondContact NH2-OE1 2.73Å; R388-E583 IonicContact NH2-OE2 3.48Å; R388-E583 PolarHBondContact NH2-OE2 2.92Å; F579-E583 WeakPolarHBondContact O-CG 3.39Å; F579-E583 PolarHBondContact O-N 3.2Å; A580-E583 PolarHBondContact O-N 3.24Å; E583-L585 PolarHBondContact O-N 3.39Å; E583-A587 WeakPolarHBondContact O-CB 3.48Å; E583-A587 PolarHBondContact O-N 3.41Å; E583-N594 HydrophobicContact CB-CB 4.04Å; E583-N594 WeakPolarHBondContact OE1-CA 3.17Å; E583-E595 PolarHBondContact OE1-N 2.72Å; E583-E595 VanDerWaalsContact OE1-N 3.09Å
584Q96Very high94.8Very high30 Ų3036.9 Ų36.914%0.1420%0.195CC..Hα-helixtrans-62.1-42.5175.7-66.4-50.5-54.300112.6A580 M581 I582 R588 N594 E595 V597A580-Q584 WeakPolarHBondContact O-CG 3.17Å; A580-Q584 PolarHBondContact O-N 3.17Å; A580-Q584 VanDerWaalsContact O-N 3.11Å; M581-Q584 PolarHBondContact O-N 3.43Å; I582-Q584 VanDerWaalsContact C-N 3.29Å; I582-Q584 PolarHBondContact O-N 2.52Å; Q584-R588 WeakPolarHBondContact O-CD 3.22Å; Q584-R588 WeakPolarHBondContact O-CG 3.43Å; Q584-R588 PolarHBondContact O-N 3.48Å; Q584-N594 VanDerWaalsContact CD-ND2 3.33Å; Q584-N594 PolarHBondContact NE2-ND2 2.86Å; Q584-N594 PolarHBondContact OE1-ND2 3.4Å; Q584-N594 VanDerWaalsContact OE1-ND2 3.13Å; Q584-E595 PolarHBondContact NE2-O 3.35Å; Q584-V597 HydrophobicContact CG-CG2 3.45Å; Q584-V597 VanDerWaalsContact CG-CG2 3.45Å
585L97.1Very high94.7Very high16 Ų1641.9 Ų41.98%0.08422%0.218CC..Hα-helixtrans-62.2-54.3177.9177.467.1000110.4C466 G467 V468 P526 L528 M581 I582 E583 A587 R588 C589C466-L585 HydrophobicContact CB-CD1 4.33Å; C466-L585 HydrophobicContact CB-CD2 4.46Å; C466-L585 HydrophobicContact CB-CG 4.36Å; G467-L585 WeakPolarHBondContact O-CD2 3.38Å; V468-L585 HydrophobicContact CG2-CD2 3.74Å; P526-L585 HydrophobicContact CB-CD1 3.7Å; L528-L585 HydrophobicContact CB-CD2 3.9Å; M581-L585 PolarHBondContact O-N 3.3Å; I582-L585 PolarHBondContact O-N 3.05Å; I582-L585 VanDerWaalsContact O-N 3.13Å; E583-L585 PolarHBondContact O-N 3.39Å; L585-A587 PolarHBondContact O-N 2.75Å; L585-R588 WeakPolarHBondContact O-CB 3.4Å; L585-R588 PolarHBondContact O-N 3.27Å; L585-R588 VanDerWaalsContact O-N 3.11Å; L585-C589 PolarHBondContact O-N 3.15Å; L585-C589 PolarHBondContact O-SG 3.38Å
586F97.8Very high94.5Very high0 Ų044 Ų440%024%0.237CC..Hα-helixtrans-66.9-34.2-175.9-66.8-18.8000113I363 L385 Y390 A442 M444 V468 I582 R588 C589 L590I363-F586 HydrophobicContact CD1-CD1 4.33Å; I363-F586 HydrophobicContact CD1-CD2 3.76Å; I363-F586 HydrophobicContact CD1-CE1 4.34Å; I363-F586 HydrophobicContact CD1-CE2 3.75Å; I363-F586 HydrophobicContact CD1-CG 4.06Å; I363-F586 HydrophobicContact CD1-CZ 4.05Å; I363-F586 HydrophobicContact CG1-CD2 4.43Å; I363-F586 HydrophobicContact CG1-CE2 4.23Å; I363-F586 HydrophobicContact CG2-CE2 4.02Å; I363-F586 HydrophobicContact CG2-CZ 4.08Å; L385-F586 HydrophobicContact CD2-CD2 3.83Å; L385-F586 HydrophobicContact CD2-CE2 3.77Å; Y390-F586 HydrophobicContact CE2-CB 3.97Å; Y390-F586 HydrophobicContact CE2-CD2 4.39Å; Y390-F586 VanDerWaalsContact OH-CB 3.26Å; Y390-F586 WeakPolarHBondContact OH-CB 3.35Å; Y390-F586 PolarHBondContact OH-O 3.38Å; Y390-F586 VanDerWaalsContact OH-O 3.13Å; A442-F586 HydrophobicContact CB-CD1 3.96Å; A442-F586 HydrophobicContact CB-CE1 3.48Å; A442-F586 VanDerWaalsContact CB-CE1 3.48Å; A442-F586 HydrophobicContact CB-CZ 4.07Å; M444-F586 HydrophobicContact CB-CZ 4.32Å; M444-F586 HydrophobicContact CG-CZ 4.47Å; M444-F586 HydrophobicContact SD-CE2 3.8Å; M444-F586 HydrophobicContact SD-CZ 3.89Å; V468-F586 HydrophobicContact CG2-CE1 3.73Å; V468-F586 HydrophobicContact CG2-CZ 3.63Å; I582-F586 HydrophobicContact CG2-CD2 3.57Å; I582-F586 HydrophobicContact CG2-CE2 3.4Å; I582-F586 HydrophobicContact CG2-CG 4.36Å; I582-F586 HydrophobicContact CG2-CZ 4.06Å; I582-F586 PolarHBondContact O-N 3.01Å; F586-R588 VanDerWaalsContact C-N 3.31Å; F586-R588 PolarHBondContact O-N 2.87Å; F586-C589 VanDerWaalsContact CA-SG 3.6Å; F586-C589 PolarHBondContact O-N 2.98Å; F586-L590 HydrophobicContact CB-CD1 4.37Å; F586-L590 HydrophobicContact CD1-CD1 4.46Å; F586-L590 HydrophobicContact CG-CD1 4.47Å; F586-L590 WeakPolarHBondContact O-CA 3.49Å; F586-L590 VanDerWaalsContact O-CB 3.28Å; F586-L590 WeakPolarHBondContact O-CB 3.13Å; F586-L590 PolarHBondContact O-N 2.86Å
587A95.8Very high94.4Very high15 Ų1541.4 Ų41.412%0.12422%0.224CC..Hα-helixtrans-59.8-42.9171.400000111.4Y390 E583 L585 N591 N594Y390-A587 PolarHBondContact OH-N 2.96Å; E583-A587 WeakPolarHBondContact O-CB 3.48Å; E583-A587 PolarHBondContact O-N 3.41Å; L585-A587 PolarHBondContact O-N 2.75Å; A587-N591 VanDerWaalsContact O-CA 3.31Å; A587-N591 WeakPolarHBondContact O-CA 3.31Å; A587-N591 PolarHBondContact O-N 2.76Å; A587-N591 VanDerWaalsContact O-N 3.07Å; A587-N594 HydrophobicContact CB-CB 3.85Å
588R94.4Very high94Very high161 Ų16144.2 Ų44.261%0.60825%0.254SS*.Hα-helixtrans-68.7-39.9179.7-69.4170.6-167.6-171.24.2113.7Q584 L585 F586Q584-R588 WeakPolarHBondContact O-CD 3.22Å; Q584-R588 WeakPolarHBondContact O-CG 3.43Å; Q584-R588 PolarHBondContact O-N 3.48Å; L585-R588 WeakPolarHBondContact O-CB 3.4Å; L585-R588 PolarHBondContact O-N 3.27Å; L585-R588 VanDerWaalsContact O-N 3.11Å; F586-R588 VanDerWaalsContact C-N 3.31Å; F586-R588 PolarHBondContact O-N 2.87Å
589C95.6Very high93.6Very high30 Ų3048 Ų4820%0.20327%0.274CS..Hα-helixtrans-91.6-23.8-176.148.90000114.4Q465 C466 L585 F586Q465-C589 HydrophobicContact CB-CB 4.42Å; C466-C589 HydrophobicContact CB-CB 3.65Å; C466-C589 WeakPolarHBondContact CB-SG 3.37Å; C466-C589 WeakPolarHBondContact SG-CB 3.12Å; C466-C589 CovalentContact SG-SG 2.03Å; C466-C589 PolarHBondContact SG-SG 2.83Å; L585-C589 PolarHBondContact O-N 3.15Å; L585-C589 PolarHBondContact O-SG 3.38Å; F586-C589 VanDerWaalsContact CA-SG 3.6Å; F586-C589 PolarHBondContact O-N 2.98Å
590L96Very high93.2Very high1 Ų147.7 Ų47.71%0.00528%0.276CS..Hα-helixtrans-122.5-6.2-171.5-55.2177000114.2A361 I363 Y390 R440 A442 Q465 F586 G592A361-L590 HydrophobicContact CB-CB 3.9Å; A361-L590 HydrophobicContact CB-CD1 4.31Å; A361-L590 HydrophobicContact CB-CG 4.48Å; I363-L590 HydrophobicContact CD1-CD1 3.36Å; Y390-L590 HydrophobicContact CD1-CD1 4.18Å; Y390-L590 HydrophobicContact CE1-CB 3.8Å; Y390-L590 HydrophobicContact CE1-CD1 3.86Å; R440-L590 HydrophobicContact CB-CD2 4.16Å; R440-L590 PolarHBondContact NH1-O 3.38Å; A442-L590 HydrophobicContact CB-CD1 3.93Å; Q465-L590 HydrophobicContact CB-CD2 4.07Å; Q465-L590 HydrophobicContact CG-CD2 4.36Å; F586-L590 HydrophobicContact CB-CD1 4.37Å; F586-L590 HydrophobicContact CD1-CD1 4.46Å; F586-L590 HydrophobicContact CG-CD1 4.47Å; F586-L590 WeakPolarHBondContact O-CA 3.49Å; F586-L590 VanDerWaalsContact O-CB 3.28Å; F586-L590 WeakPolarHBondContact O-CB 3.13Å; F586-L590 PolarHBondContact O-N 2.86Å; L590-G592 VanDerWaalsContact C-N 3.34Å
591N88.4Confident92.9Very high134 Ų13449.6 Ų49.672%0.71729%0.285SS*.  trans58.239.2-174.6-61.3-24.8000113.7A587A587-N591 VanDerWaalsContact O-CA 3.31Å; A587-N591 WeakPolarHBondContact O-CA 3.31Å; A587-N591 PolarHBondContact O-N 2.76Å; A587-N591 VanDerWaalsContact O-N 3.07Å
592G84.3Confident92.6Very high19 Ų1954.7 Ų54.720%0.19631%0.308CS..  trans-85.1170.5168.600000112.3Y390 L590Y390-G592 VanDerWaalsContact OH-CA 3.26Å; Y390-G592 WeakPolarHBondContact OH-CA 3.17Å; Y390-G592 PolarHBondContact OH-N 2.91Å; L590-G592 VanDerWaalsContact C-N 3.34Å
593S91Very high92.1Very high63 Ų6361.7 Ų61.744%0.44135%0.346SS..  trans-75.5149.5174.855.80000111R388R388-S593 VanDerWaalsContact CA-OG 3.25Å; R388-S593 WeakPolarHBondContact CA-OG 3.42Å; R388-S593 VanDerWaalsContact CB-O 3.31Å; R388-S593 WeakPolarHBondContact CB-O 3.3Å; R388-S593 WeakPolarHBondContact CD-O 3.03Å; R388-S593 WeakPolarHBondContact CG-O 3.26Å; R388-S593 PolarHBondContact O-N 3.33Å; R388-S593 PolarHBondContact O-OG 2.93Å
594N93.8Very high91.8Very high65 Ų6562.4 Ų62.435%0.34835%0.35SS..  trans-140.8156.5174.159.6-28.9000111E583 Q584 A587E583-N594 HydrophobicContact CB-CB 4.04Å; E583-N594 WeakPolarHBondContact OE1-CA 3.17Å; Q584-N594 VanDerWaalsContact CD-ND2 3.33Å; Q584-N594 PolarHBondContact NE2-ND2 2.86Å; Q584-N594 PolarHBondContact OE1-ND2 3.4Å; Q584-N594 VanDerWaalsContact OE1-ND2 3.13Å; A587-N594 HydrophobicContact CB-CB 3.85Å
595E93Very high91.6Very high111 Ų11165.8 Ų65.852%0.51937%0.369SS..  trans-87.3151.2162.2-77.1177.3-147.800111.3R388 E583 Q584R388-E595 IonicContact CZ-OE1 3.32Å; R388-E595 IonicContact NH1-OE1 2.98Å; R388-E595 PolarHBondContact NH1-OE1 3.31Å; R388-E595 IonicContact NH2-OE1 3.78Å; R388-E595 PolarHBondContact NH2-OE1 2.86Å; R388-E595 IonicContact NH2-OE2 3.08Å; E583-E595 PolarHBondContact OE1-N 2.72Å; E583-E595 VanDerWaalsContact OE1-N 3.09Å; Q584-E595 PolarHBondContact NE2-O 3.35Å
596P91.3Very high91.5Very high114 Ų11466.5 Ų66.574%0.7437%0.373SS*.  trans-57.3143.2169.3-20.232.2000110.3G598P596-G598 PolarHBondContact O-N 2.89Å; P596-G598 VanDerWaalsContact O-N 3.11Å
597V91Very high91.4Very high32 Ų3269.4 Ų69.419%0.19439%0.39CS..  trans-56.4-31.8177.2179.60000111.8A580 M581 Q584 D599 S600 L601A580-V597 HydrophobicContact CB-CG1 4.38Å; M581-V597 HydrophobicContact SD-CG2 4.39Å; Q584-V597 HydrophobicContact CG-CG2 3.45Å; Q584-V597 VanDerWaalsContact CG-CG2 3.45Å; V597-D599 PolarHBondContact O-N 3.17Å; V597-S600 WeakPolarHBondContact O-CB 3.3Å; V597-S600 PolarHBondContact O-N 2.86Å; V597-S600 VanDerWaalsContact O-N 3.11Å; V597-S600 PolarHBondContact O-OG 2.86Å; V597-L601 HydrophobicContact CG1-CD1 3.65Å; V597-L601 HydrophobicContact CG1-CG 3.68Å
598G87.9Confident91.3Very high60 Ų6071.5 Ų71.562%0.61940%0.399SS*.THydrogen-bonded Turntrans56.3-135.3174.700000112.2P596 S600P596-G598 PolarHBondContact O-N 2.89Å; P596-G598 VanDerWaalsContact O-N 3.11Å; G598-S600 VanDerWaalsContact C-N 3.31Å
599D88.4Confident91.4Very high86 Ų8667.2 Ų67.246%0.4639%0.386SS..THydrogen-bonded Turntrans-87.56.3177.768.6-40.1000113.4R573 V597 L601 E602R573-D599 IonicContact NH1-OD2 2.75Å; V597-D599 PolarHBondContact O-N 3.17Å; D599-L601 PolarHBondContact O-N 3.47Å; D599-E602 HydrophobicContact CB-CB 4.33Å; D599-E602 HydrophobicContact CB-CG 4.2Å; D599-E602 WeakPolarHBondContact O-CB 3.33Å; D599-E602 PolarHBondContact O-N 2.74Å
600S88.5Confident91.3Very high25 Ų2570 Ų7018%0.17540%0.396CS..THydrogen-bonded Turntrans-59.3-25.3-177.1-51.60000113.1A577 V597 G598A577-S600 WeakPolarHBondContact CB-O 3.23Å; V597-S600 WeakPolarHBondContact O-CB 3.3Å; V597-S600 PolarHBondContact O-N 2.86Å; V597-S600 VanDerWaalsContact O-N 3.11Å; V597-S600 PolarHBondContact O-OG 2.86Å; G598-S600 VanDerWaalsContact C-N 3.31Å
601L90.7Very high91.3Very high52 Ų5271.9 Ų71.927%0.27240%0.403SS..THydrogen-bonded Turntrans-98.3-6.5177-61.2176.6000113.3A577 M581 V597 D599 L608A577-L601 HydrophobicContact CB-CD2 3.81Å; M581-L601 HydrophobicContact SD-CD1 4.3Å; V597-L601 HydrophobicContact CG1-CD1 3.65Å; V597-L601 HydrophobicContact CG1-CG 3.68Å; D599-L601 PolarHBondContact O-N 3.47Å; L601-L608 HydrophobicContact CD1-CD2 3.61Å; L601-L608 HydrophobicContact CD2-CD2 4.13Å
602E89.4Confident91.3Very high116 Ų11669.7 Ų69.754%0.54240%0.396SS..THydrogen-bonded Turntrans-74.3132.2-175.4-71.4-174.3-176.600111.8R573 D599 L604R573-E602 PolarHBondContact NH2-O 3.49Å; D599-E602 HydrophobicContact CB-CB 4.33Å; D599-E602 HydrophobicContact CB-CG 4.2Å; D599-E602 WeakPolarHBondContact O-CB 3.33Å; D599-E602 PolarHBondContact O-N 2.74Å; E602-L604 PolarHBondContact O-N 2.78Å
603N87.2Confident91.1Very high147 Ų14773 Ų7379%0.78641%0.409SS*.THydrogen-bonded Turntrans57.423.2-179.9-53.4-57.2000114.3
604L90.6Very high89.7Confident34 Ų3474 Ų7418%0.17842%0.421CS..  trans-91.9131.3174-172.364.6000110.1F562 R573 A577 E602 I606F562-L604 HydrophobicContact CE1-CD2 4.07Å; R573-L604 HydrophobicContact CB-CD1 3.99Å; A577-L604 HydrophobicContact CB-CD2 3.39Å; E602-L604 PolarHBondContact O-N 2.78Å; L604-I606 HydrophobicContact CB-CG2 4.35Å; L604-I606 HydrophobicContact CD2-CB 4.19Å; L604-I606 HydrophobicContact CD2-CD1 4.34Å; L604-I606 HydrophobicContact CD2-CG2 4.16Å; L604-I606 HydrophobicContact CG-CB 4.17Å; L604-I606 HydrophobicContact CG-CG2 4.21Å; L604-I606 PolarHBondContact O-N 3.5Å; L604-I606 VanDerWaalsContact O-N 3.16Å
605D91.2Very high87.3Confident100 Ų10081 Ų8154%0.53545%0.449SS..  trans-76.599.4169.1-170.918.2000108.5P563P563-D605 WeakPolarHBondContact CD-O 3.3Å
606I94.6Very high84.4Confident32 Ų3281.7 Ų81.716%0.16445%0.454CS..  trans-150.2140.8-177-168.2-179.6000109.9M560 V561 F562 L604 L608M560-I606 HydrophobicContact CB-CD1 4.32Å; M560-I606 HydrophobicContact CE-CD1 3.55Å; V561-I606 WeakPolarHBondContact O-CA 2.93Å; V561-I606 WeakPolarHBondContact O-CG1 3.22Å; F562-I606 HydrophobicContact CD1-CD1 3.9Å; F562-I606 HydrophobicContact CD1-CG1 4Å; F562-I606 HydrophobicContact CE1-CD1 3.4Å; F562-I606 HydrophobicContact CE1-CG1 4.03Å; F562-I606 HydrophobicContact CE2-CD1 4.14Å; F562-I606 HydrophobicContact CG-CD1 4.47Å; F562-I606 HydrophobicContact CG-CG1 4.37Å; F562-I606 HydrophobicContact CZ-CD1 3.54Å; F562-I606 HydrophobicContact CZ-CG1 4.42Å; L604-I606 HydrophobicContact CB-CG2 4.35Å; L604-I606 HydrophobicContact CD2-CB 4.19Å; L604-I606 HydrophobicContact CD2-CD1 4.34Å; L604-I606 HydrophobicContact CD2-CG2 4.16Å; L604-I606 HydrophobicContact CG-CB 4.17Å; L604-I606 HydrophobicContact CG-CG2 4.21Å; L604-I606 PolarHBondContact O-N 3.5Å; L604-I606 VanDerWaalsContact O-N 3.16Å; I606-L608 HydrophobicContact CG2-CB 4.47Å
607T95.8Very high81.5Confident61 Ų6186 Ų8637%0.37446%0.461SS..EExtended strand (participates in β ladder)trans-88.4111.3161.5-58.30000108.1Y559 M560 V561 E609Y559-T607 HydrophobicContact CD1-CG2 4.49Å; M560-T607 CarbonylContact C-O 3.34Å; M560-T607 VanDerWaalsContact CA-O 3.29Å; M560-T607 WeakPolarHBondContact CA-O 3.08Å; V561-T607 PolarHBondContact N-O 2.84Å; V561-T607 PolarHBondContact O-N 3.01Å; T607-E609 HydrophobicContact CG2-CG 4.32Å
608L95.3Very high78.4Confident59 Ų5995.7 Ų95.731%0.30949%0.494SS..EExtended strand (participates in β ladder)trans-121.4116.5178.1175.465.8000110T558 Y559 M560 M581 L601 I606T558-L608 HydrophobicContact CG2-CD1 3.66Å; Y559-L608 WeakPolarHBondContact O-CA 3.45Å; M560-L608 HydrophobicContact CE-CD1 4.43Å; M560-L608 HydrophobicContact CG-CD1 3.58Å; M560-L608 HydrophobicContact SD-CD1 4.18Å; M581-L608 HydrophobicContact CE-CD1 4.24Å; L601-L608 HydrophobicContact CD1-CD2 3.61Å; L601-L608 HydrophobicContact CD2-CD2 4.13Å; I606-L608 HydrophobicContact CG2-CB 4.47Å
609E95.7Very high75.5Confident71 Ų71102.9 Ų102.933%0.33250%0.502SS..EExtended strand (participates in β ladder)trans-129.2141.9177.5-54.3-176.6157.700110.6T558 Y559 T607 Y611T558-E609 CarbonylContact C-O 3.58Å; T558-E609 WeakPolarHBondContact CA-O 3.49Å; Y559-E609 PolarHBondContact N-O 2.92Å; Y559-E609 PolarHBondContact O-N 2.83Å; T607-E609 HydrophobicContact CG2-CG 4.32Å; E609-Y611 HydrophobicContact CB-CD2 4.32Å; E609-Y611 HydrophobicContact CB-CE2 3.62Å; E609-Y611 VanDerWaalsContact OE2-CE2 3.29Å; E609-Y611 WeakPolarHBondContact OE2-CE2 3.29Å; E609-Y611 VanDerWaalsContact OE2-CZ 3.28Å; E609-Y611 PolarHBondContact OE2-OH 2.67Å
610Q94.4Very high72.5Confident89 Ų89107 Ų10742%0.41652%0.518SS..EExtended strand (participates in β ladder)trans-119.2125174.9-73.3-176.315.300110.3T558 L613T558-Q610 HydrophobicContact CG2-CG 4.21Å; Q610-L613 WeakPolarHBondContact O-CA 3.35Å
611Y95Very high69.6Low39 Ų39115.5 Ų115.515%0.15355%0.547CS..EExtended strand (participates in β ladder)trans-110.8149.8-177.2-70.6-86.6000112.3V551 N556 F557 E609 L613V551-Y611 HydrophobicContact CG1-CE1 4.36Å; V551-Y611 HydrophobicContact CG2-CD1 3.62Å; V551-Y611 HydrophobicContact CG2-CD2 4.44Å; V551-Y611 HydrophobicContact CG2-CE1 3.42Å; V551-Y611 VanDerWaalsContact CG2-CE1 3.42Å; V551-Y611 HydrophobicContact CG2-CE2 4.29Å; V551-Y611 HydrophobicContact CG2-CG 4.13Å; N556-Y611 VanDerWaalsContact CA-O 3.27Å; N556-Y611 WeakPolarHBondContact CA-O 3.38Å; N556-Y611 PolarHBondContact OD1-O 2.79Å; N556-Y611 VanDerWaalsContact OD1-O 3.11Å; F557-Y611 HydrophobicContact CD1-CD2 4.14Å; F557-Y611 HydrophobicContact CD1-CG 4.09Å; F557-Y611 HydrophobicContact CD2-CD2 4.44Å; F557-Y611 VanDerWaalsContact CE1-CB 3.46Å; F557-Y611 HydrophobicContact CE1-CD1 4.29Å; F557-Y611 AromaticContact CE1-CD2 3.5Å; F557-Y611 HydrophobicContact CE1-CD2 3.5Å; F557-Y611 VanDerWaalsContact CE1-CD2 3.5Å; F557-Y611 HydrophobicContact CE1-CE2 4.31Å; F557-Y611 AromaticContact CE1-CG 3.48Å; F557-Y611 HydrophobicContact CE1-CG 3.48Å; F557-Y611 VanDerWaalsContact CE1-CG 3.48Å; F557-Y611 AromaticContact CE2-CD2 3.86Å; F557-Y611 HydrophobicContact CE2-CD2 3.86Å; F557-Y611 HydrophobicContact CE2-CE2 4.29Å; F557-Y611 AromaticContact CZ-CD2 3.32Å; F557-Y611 HydrophobicContact CZ-CD2 3.32Å; F557-Y611 AromaticContact CZ-CE2 3.76Å; F557-Y611 HydrophobicContact CZ-CE2 3.76Å; F557-Y611 AromaticContact CZ-CG 3.82Å; F557-Y611 HydrophobicContact CZ-CG 3.82Å; F557-Y611 PolarHBondContact N-O 2.78Å; F557-Y611 PolarHBondContact O-N 2.82Å; E609-Y611 HydrophobicContact CB-CD2 4.32Å; E609-Y611 HydrophobicContact CB-CE2 3.62Å; E609-Y611 VanDerWaalsContact OE2-CE2 3.29Å; E609-Y611 WeakPolarHBondContact OE2-CE2 3.29Å; E609-Y611 VanDerWaalsContact OE2-CZ 3.28Å; E609-Y611 PolarHBondContact OE2-OH 2.67Å; Y611-L613 HydrophobicContact CD1-CD1 4.4Å; Y611-L613 HydrophobicContact CD1-CG 3.87Å; Y611-L613 HydrophobicContact CE1-CD1 3.74Å; Y611-L613 HydrophobicContact CE1-CD2 4.38Å; Y611-L613 HydrophobicContact CE1-CG 3.66Å
612P89.3Confident66.5Low88 Ų88119 Ų11957%0.57157%0.57SS**SBendcis-62.4137.1-9.528.6-34.3000109.5A614P612-A614 PolarHBondContact O-N 3.38Å
613L78.5Confident63.4Low88 Ų88121.6 Ų121.646%0.46158%0.579SS.*  trans-54.1116.5177.5-70.7166.9000106.7Q610 Y611 K615Q610-L613 WeakPolarHBondContact O-CA 3.35Å; Y611-L613 HydrophobicContact CD1-CD1 4.4Å; Y611-L613 HydrophobicContact CD1-CG 3.87Å; Y611-L613 HydrophobicContact CE1-CD1 3.74Å; Y611-L613 HydrophobicContact CE1-CD2 4.38Å; Y611-L613 HydrophobicContact CE1-CG 3.66Å; L613-K615 PolarHBondContact O-N 3Å
614A62.6Low60.6Low85 Ų85120 Ų12070%0.70258%0.575SS**  trans-45.4123.3176.600000106.7P612 M616P612-A614 PolarHBondContact O-N 3.38Å; A614-M616 VanDerWaalsContact C-N 3.27Å; A614-M616 VanDerWaalsContact O-CA 3.31Å; A614-M616 WeakPolarHBondContact O-CA 2.72Å; A614-M616 PolarHBondContact O-N 3.22Å
615K42.5Very low57.5Low211 Ų211127.1 Ų127.192%0.91761%0.607SS**  trans-42.296.3-173.9-85.2-176.2176.8176.80108.4L613 K617L613-K615 PolarHBondContact O-N 3Å; K615-K617 PolarHBondContact O-N 3.15Å
616M32.6Very low54.4Low127 Ų127125.6 Ų125.663%0.62662%0.616SS**  trans-69.2104.8-169-92.9-167.9-178.800105.7A614 R618A614-M616 VanDerWaalsContact C-N 3.27Å; A614-M616 VanDerWaalsContact O-CA 3.31Å; A614-M616 WeakPolarHBondContact O-CA 2.72Å; A614-M616 PolarHBondContact O-N 3.22Å; M616-R618 PolarHBondContact O-N 2.59Å
617K30.1Very low51.2Low205 Ų205133.9 Ų133.989%0.89165%0.65SS**SBendtrans-58.596.7151.6-78.2-176.8176.1178.80105.3K615K615-K617 PolarHBondContact O-N 3.15Å
618R26.3Very low47.9Very low234 Ų234138.4 Ų138.488%0.88367%0.672SS**SBendtrans48.9103.7170.8-110.5177172.1179.5-2.7114.7M616 E620M616-R618 PolarHBondContact O-N 2.59Å; R618-E620 PolarHBondContact O-N 2.81Å
619R27.5Very low44.6Very low212 Ų212146.7 Ų146.780%0.870%0.7SS**  trans-13.696.4161.1-74.9177167.4173.8-4.3114.1R621R619-R621 PolarHBondContact O-N 2.71Å
620E24.3Very low41.2Very low171 Ų171152.2 Ų152.280%0.79973%0.725SS**  trans-83.4100.3147.2-82.2-177.1165.600105.9R618 V622R618-E620 PolarHBondContact O-N 2.81Å; E620-V622 PolarHBondContact O-N 2.94Å
621R27.6Very low38Very low204 Ų204156.2 Ų156.277%0.7774%0.743SS**  trans-67.5106.2157.1-88.2-178.5173.5177-4.1105.5R619 K623R619-R621 PolarHBondContact O-N 2.71Å; R621-K623 PolarHBondContact O-N 3.15Å
622V25.5Very low34.7Very low125 Ų125160 Ų16076%0.75878%0.775SS**  trans-68.189.9156.4-178.50000105.7E620 V624E620-V622 PolarHBondContact O-N 2.94Å; V622-V624 HydrophobicContact CG1-CG2 4.31Å; V622-V624 PolarHBondContact O-N 2.95Å
623K25.1Very low31.8Very low171 Ų171168.9 Ų168.974%0.74381%0.806SS**  trans-73.9108.2157.5-99.5-173.1171-172.20105.3R621 E625R621-K623 PolarHBondContact O-N 3.15Å; K623-E625 PolarHBondContact O-N 3.09Å
624V28Very low29.5Very low115 Ų115172.9 Ų172.970%0.69782%0.823SS**  trans-66.2113.6157-179.80000105.6V622 G626V622-V624 HydrophobicContact CG1-CG2 4.31Å; V622-V624 PolarHBondContact O-N 2.95Å; V624-G626 PolarHBondContact O-N 2.85Å
625E25.2Very low27.7Very low182 Ų182177.5 Ų177.585%0.8583%0.829SS**  trans-6687.4169.7-77.8-171.7156.100108.7K623 K627K623-E625 PolarHBondContact O-N 3.09Å; E625-K627 PolarHBondContact O-N 3.49Å; E625-K627 VanDerWaalsContact O-N 3.13Å
626G26.6Very low26.9Very low69 Ų69175.7 Ų175.771%0.71182%0.824SS**  trans-64.2106.1158.100000108.4V624 N628V624-G626 PolarHBondContact O-N 2.85Å; G626-N628 PolarHBondContact O-N 3.26Å; G626-N628 VanDerWaalsContact O-N 3.14Å
627K27.9Very low26.6Very low205 Ų205178.5 Ų178.589%0.89184%0.836SS**  trans-52.5118.2167.7-82.5179.6175.2174.20109.4E625 R629E625-K627 PolarHBondContact O-N 3.49Å; E625-K627 VanDerWaalsContact O-N 3.13Å; K627-R629 PolarHBondContact O-N 2.86Å
628N25.6Very low26.3Very low156 Ų156176.9 Ų176.983%0.83483%0.833SS**  trans8.6103.1154.5-74-20.4000116.4G626G626-N628 PolarHBondContact O-N 3.26Å; G626-N628 VanDerWaalsContact O-N 3.14Å
629R27.2Very low26.3Very low234 Ų234173.1 Ų173.188%0.88383%0.829SS**  trans-13396.4138.7-76.5-168.1175.7177.6-0.7109.2K627 H631K627-R629 PolarHBondContact O-N 2.86Å; R629-H631 PolarHBondContact O-N 2.63Å
630Q23.4Very low26.3Very low187 Ų187170.3 Ų170.387%0.87483%0.831SS**  trans-62.7110.6155.8-82.9-179.4-32.400107.7
631H27.9Very low26.4Very low172 Ų172170.2 Ų170.280%0.79683%0.834SS**  trans-133.9108.9145-83.6-54.4000107.8R629R629-H631 PolarHBondContact O-N 2.63Å
632S24.7Very low26.3Very low118 Ų118167.4 Ų167.483%0.82584%0.839SS**  trans-61.1127.5161.452.20000109.1
633F28.6Very low26.4Very low275 Ų275171.3 Ų171.3100%1.20685%0.847SS**  trans-94.90151.2-98.7-83.2000109

Retrieved 633 of 633 residues in 325.6 ms (Link to these results)