A0A077YVN7_TRITR Loading...

Endonuclease

AlphaFold DB , UniProt , Accession A0A077YVN7, Species TRITR (Trichuris trichiura, Whipworm), Gene n/a, Length 229 aa.

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Site Residue pLDDT pLDDT confidence pLDDT10 pLDDT10 confidence SASA SASA [Ų] SASA10 SASA10 [Ų] RSA RSA unformatted RSA10 RSA10 unformatted Surface Surface10 (not used) Disorder (not used) Disorder Sec. str. Secondary structure Isomer Phi (φ) Psi (ψ) Omega (ω) Chi 1 (χ1) Chi 2 (χ2) Chi 3 (χ3) Chi 4 (χ4) Chi 5 (χ5) Tau (τ) Contacts (colored by PAE) Contact details
1M97.4Very high97Very high58 Ų5864.4 Ų64.429%0.28631%0.308SS..  019.30-52.1-45.2-73.200114.5F3 G4 Y5 V18 W27 M29M1-F3 PolarHBondContact O-N 2.81Å; M1-G4 PolarHBondContact O-N 2.7Å; M1-Y5 HydrophobicContact CB-CD2 4.23Å; M1-Y5 HydrophobicContact CB-CE1 4.43Å; M1-Y5 HydrophobicContact CB-CE2 3.64Å; M1-Y5 HydrophobicContact CE-CD1 3.3Å; M1-Y5 HydrophobicContact CE-CD2 4.03Å; M1-Y5 HydrophobicContact CE-CE1 3.58Å; M1-Y5 HydrophobicContact CE-CE2 4.27Å; M1-Y5 HydrophobicContact CE-CG 3.53Å; M1-Y5 HydrophobicContact CG-CD1 4.5Å; M1-Y5 HydrophobicContact CG-CE1 3.84Å; M1-Y5 HydrophobicContact CG-CE2 3.97Å; M1-Y5 HydrophobicContact SD-CE1 4.41Å; M1-V18 HydrophobicContact CG-CG2 3.91Å; M1-V18 HydrophobicContact SD-CB 3.93Å; M1-V18 HydrophobicContact SD-CG1 4.22Å; M1-V18 HydrophobicContact SD-CG2 3.9Å; M1-W27 HydrophobicContact CE-CH2 3.7Å; M1-W27 HydrophobicContact CE-CZ3 3.89Å; M1-M29 HydrophobicContact CE-CB 4.22Å; M1-M29 HydrophobicContact CE-CE 4.41Å; M1-M29 HydrophobicContact CE-CG 4.27Å; M1-M29 HydrophobicContact SD-CB 3.57Å; M1-M29 VanDerWaalsContact SD-CB 3.57Å; M1-M29 HydrophobicContact SD-CG 3.56Å; M1-M29 VanDerWaalsContact SD-CG 3.56Å
2R96.7Very high97.1Very high152 Ų15265.6 Ų65.657%0.57431%0.307SS*.THydrogen-bonded Turntrans-55.7-35.7-177.9-178.1178179.1-174.8-3113.9Y130R2-Y130 HydrophobicContact CB-CE1 4.12Å; R2-Y130 WeakPolarHBondContact CD-OH 3.41Å
3F96.9Very high97.2Very high18 Ų1868.8 Ų68.88%0.07933%0.334CS..THydrogen-bonded Turntrans-100.523-175-59.3-63.5000113.9M1 Y130 L170 W178 F215 Q216 N217 L218M1-F3 PolarHBondContact O-N 2.81Å; F3-Y130 HydrophobicContact CD2-CD1 4.21Å; F3-Y130 HydrophobicContact CD2-CD2 4.04Å; F3-Y130 HydrophobicContact CD2-CE1 4.34Å; F3-Y130 HydrophobicContact CD2-CE2 4.23Å; F3-Y130 HydrophobicContact CD2-CG 4.04Å; F3-Y130 HydrophobicContact CE2-CD1 4.34Å; F3-Y130 AromaticContact CE2-CD2 3.62Å; F3-Y130 HydrophobicContact CE2-CD2 3.62Å; F3-Y130 HydrophobicContact CE2-CE1 4.15Å; F3-Y130 AromaticContact CE2-CE2 3.45Å; F3-Y130 HydrophobicContact CE2-CE2 3.45Å; F3-Y130 VanDerWaalsContact CE2-CE2 3.45Å; F3-Y130 HydrophobicContact CE2-CG 4.07Å; F3-Y130 AromaticContact CE2-CZ 3.71Å; F3-Y130 HydrophobicContact CZ-CE2 4.39Å; F3-L170 HydrophobicContact CD2-CD2 3.49Å; F3-L170 VanDerWaalsContact CD2-CD2 3.49Å; F3-L170 HydrophobicContact CE2-CD2 3.69Å; F3-L170 HydrophobicContact CG-CD2 3.99Å; F3-L170 HydrophobicContact CZ-CD2 4.37Å; F3-W178 HydrophobicContact CE1-CH2 4.47Å; F3-W178 AromaticContact CE2-CH2 3.59Å; F3-W178 HydrophobicContact CE2-CH2 3.59Å; F3-W178 AromaticContact CE2-CZ3 3.68Å; F3-W178 HydrophobicContact CE2-CZ3 3.68Å; F3-W178 AromaticContact CZ-CH2 3.3Å; F3-W178 HydrophobicContact CZ-CH2 3.3Å; F3-W178 AromaticContact CZ-CZ2 3.81Å; F3-W178 HydrophobicContact CZ-CZ2 3.81Å; F3-W178 AromaticContact CZ-CZ3 3.75Å; F3-W178 HydrophobicContact CZ-CZ3 3.75Å; F3-F215 HydrophobicContact CB-CB 4.04Å; F3-F215 HydrophobicContact CB-CD1 3.92Å; F3-F215 HydrophobicContact CB-CG 4.41Å; F3-F215 CarbonylContact O-C 3.25Å; F3-F215 VanDerWaalsContact O-C 3.25Å; F3-F215 VanDerWaalsContact O-CA 3.28Å; F3-F215 WeakPolarHBondContact O-CA 3.41Å; F3-Q216 PolarHBondContact O-N 3.02Å; F3-N217 PolarHBondContact O-N 3.49Å; F3-L218 HydrophobicContact CD1-CB 3.95Å; F3-L218 HydrophobicContact CD1-CD1 4.05Å; F3-L218 HydrophobicContact CE1-CB 4.45Å; F3-L218 HydrophobicContact CE1-CD1 3.67Å; F3-L218 HydrophobicContact CG-CB 4.48Å; F3-L218 HydrophobicContact CZ-CD1 4.23Å
4G96.9Very high97.3Very high7 Ų765.7 Ų65.77%0.07232%0.318CS..  trans97.7162.6178.400000113.4M1M1-G4 PolarHBondContact O-N 2.7Å
5Y98.1Very high97.3Very high76 Ų7667.3 Ų67.330%0.29832%0.324SS..  trans-90.6134.2170.3-73.8-104.6000108.8M1 G7 F8 L11 V18 W27 Q216M1-Y5 HydrophobicContact CB-CD2 4.23Å; M1-Y5 HydrophobicContact CB-CE1 4.43Å; M1-Y5 HydrophobicContact CB-CE2 3.64Å; M1-Y5 HydrophobicContact CE-CD1 3.3Å; M1-Y5 HydrophobicContact CE-CD2 4.03Å; M1-Y5 HydrophobicContact CE-CE1 3.58Å; M1-Y5 HydrophobicContact CE-CE2 4.27Å; M1-Y5 HydrophobicContact CE-CG 3.53Å; M1-Y5 HydrophobicContact CG-CD1 4.5Å; M1-Y5 HydrophobicContact CG-CE1 3.84Å; M1-Y5 HydrophobicContact CG-CE2 3.97Å; M1-Y5 HydrophobicContact SD-CE1 4.41Å; Y5-G7 VanDerWaalsContact C-N 3.33Å; Y5-F8 HydrophobicContact CD1-CE1 4.45Å; Y5-F8 HydrophobicContact CD2-CE1 4.1Å; Y5-F8 HydrophobicContact CG-CD1 4.4Å; Y5-F8 AromaticContact CG-CE1 3.86Å; Y5-F8 HydrophobicContact CG-CE1 3.86Å; Y5-F8 HydrophobicContact CG-CZ 4.41Å; Y5-L11 HydrophobicContact CD1-CD1 3.71Å; Y5-L11 HydrophobicContact CD1-CD2 4.06Å; Y5-L11 HydrophobicContact CE1-CD1 3.72Å; Y5-L11 HydrophobicContact CE1-CD2 4.33Å; Y5-V18 HydrophobicContact CE1-CG1 4.35Å; Y5-W27 HydrophobicContact CD1-CH2 4Å; Y5-W27 HydrophobicContact CD1-CZ2 4.44Å; Y5-Q216 PolarHBondContact O-NE2 3.12Å
6P97.9Very high97.4Very high12 Ų1264.1 Ų64.18%0.07831%0.31CS..SBendtrans-64.9-38.3172.6-20.429.5000113.1W27 M29 F212 L213P6-W27 HydrophobicContact CB-CD2 4.15Å; P6-W27 HydrophobicContact CB-CG 4.18Å; P6-W27 HydrophobicContact CB-CZ2 4.5Å; P6-W27 HydrophobicContact CG-CD2 3.81Å; P6-W27 HydrophobicContact CG-CE3 4.17Å; P6-W27 HydrophobicContact CG-CG 4.16Å; P6-W27 HydrophobicContact CG-CZ2 4.3Å; P6-M29 HydrophobicContact CG-CE 3.42Å; P6-M29 VanDerWaalsContact CG-CE 3.42Å; P6-F212 HydrophobicContact CB-CB 4.04Å; P6-F212 HydrophobicContact CB-CD2 3.52Å; P6-F212 HydrophobicContact CB-CE2 4.1Å; P6-F212 HydrophobicContact CB-CG 3.92Å; P6-F212 WeakPolarHBondContact O-CB 3.48Å; P6-L213 WeakPolarHBondContact CA-O 3.49Å; P6-L213 WeakPolarHBondContact CB-O 3.46Å
7G96.4Very high97.5Very high19 Ų1960.7 Ų60.720%0.19629%0.293CS..  trans-153.3-178.4171.700000110.8Y5 W27Y5-G7 VanDerWaalsContact C-N 3.33Å; G7-W27 VanDerWaalsContact O-CZ2 3.31Å; G7-W27 WeakPolarHBondContact O-CZ2 3.28Å
8F97.2Very high97.6Very high151 Ų15158.2 Ų58.266%0.66228%0.282SS*.  trans-122.56.6-176.7-61.8-84.5000113.6Y5 N10 L11Y5-F8 HydrophobicContact CD1-CE1 4.45Å; Y5-F8 HydrophobicContact CD2-CE1 4.1Å; Y5-F8 HydrophobicContact CG-CD1 4.4Å; Y5-F8 AromaticContact CG-CE1 3.86Å; Y5-F8 HydrophobicContact CG-CE1 3.86Å; Y5-F8 HydrophobicContact CG-CZ 4.41Å; F8-N10 PolarHBondContact O-N 3.2Å; F8-L11 HydrophobicContact CB-CD1 4.47Å; F8-L11 HydrophobicContact CD1-CD1 4.02Å
9D96.4Very high97.6Very high82 Ų8255.2 Ų55.244%0.43927%0.267SS..THydrogen-bonded Turntrans-71.1126.4-177-165.717.1000111.5L11 S20 Y21 H26D9-L11 VanDerWaalsContact C-N 3.34Å; D9-L11 PolarHBondContact O-N 3.18Å; D9-L11 VanDerWaalsContact O-N 3.11Å; D9-S20 PolarHBondContact O-OG 2.79Å; D9-Y21 PolarHBondContact O-N 3.14Å; D9-H26 IonicContact OD2-CD2 3.48Å; D9-H26 IonicContact OD2-CE1 3.44Å; D9-H26 IonicContact OD2-NE2 3.57Å; D9-H26 PolarHBondContact OD2-NE2 3.19Å
10N95.8Very high97.7Very high86 Ų8652.5 Ų52.546%0.4625%0.254SS..THydrogen-bonded Turntrans3952.5177.2-64.8-55.2000115.7F8 Y21F8-N10 PolarHBondContact O-N 3.2Å; N10-Y21 WeakPolarHBondContact CB-O 3.23Å; N10-Y21 PolarHBondContact ND2-O 2.86Å
11L97.5Very high97.6Very high47 Ų4750.3 Ų50.325%0.24624%0.244CC..  trans-64140.4-179-68.3174.5000113.1Y5 F8 D9 V18 V19 W27Y5-L11 HydrophobicContact CD1-CD1 3.71Å; Y5-L11 HydrophobicContact CD1-CD2 4.06Å; Y5-L11 HydrophobicContact CE1-CD1 3.72Å; Y5-L11 HydrophobicContact CE1-CD2 4.33Å; F8-L11 HydrophobicContact CB-CD1 4.47Å; F8-L11 HydrophobicContact CD1-CD1 4.02Å; D9-L11 VanDerWaalsContact C-N 3.34Å; D9-L11 PolarHBondContact O-N 3.18Å; D9-L11 VanDerWaalsContact O-N 3.11Å; L11-V18 HydrophobicContact CD2-CG1 4.45Å; L11-V19 CarbonylContact C-O 3.58Å; L11-V19 WeakPolarHBondContact CA-O 3.28Å; L11-W27 HydrophobicContact CD2-CH2 3.56Å; L11-W27 HydrophobicContact CD2-CZ2 3.59Å
12R98.1Very high97.3Very high79 Ų7950.8 Ų50.830%0.29825%0.247SC..EExtended strand (participates in β ladder)trans-132.3133.9168.3-64.4-65.1-178.9-94.92.9109.6Y14 V18 V19 S55R12-Y14 HydrophobicContact CB-CE2 3.99Å; R12-V18 WeakPolarHBondContact O-CA 3.48Å; R12-V19 PolarHBondContact N-O 3.37Å; R12-V19 PolarHBondContact O-N 2.95Å; R12-S55 WeakPolarHBondContact CD-OG 3.26Å; R12-S55 PolarHBondContact NE-OG 3.39Å; R12-S55 PolarHBondContact NH2-O 3.3Å
13T98.2Very high96.6Very high107 Ų10748.8 Ų48.866%0.65624%0.24SC*.EExtended strand (participates in β ladder)trans-108.1116.7174.7-56.10000108.4V18T13-V18 HydrophobicContact CG2-CG2 4.3Å
14Y98.4Very high96.3Very high26 Ų2648.1 Ų48.110%0.10224%0.237CC..  trans-95.2178.7171.5-63-66.3000109.6R12 D16 F17 V19 D53 Q92 L95 S97R12-Y14 HydrophobicContact CB-CE2 3.99Å; Y14-D16 PolarHBondContact O-N 3.34Å; Y14-F17 WeakPolarHBondContact CB-O 3.09Å; Y14-F17 HydrophobicContact CD2-CD1 4.46Å; Y14-F17 AromaticContact CD2-CD2 3.94Å; Y14-F17 HydrophobicContact CD2-CD2 3.94Å; Y14-F17 AromaticContact CD2-CE1 3.94Å; Y14-F17 HydrophobicContact CD2-CE1 3.94Å; Y14-F17 AromaticContact CD2-CE2 3.38Å; Y14-F17 HydrophobicContact CD2-CE2 3.38Å; Y14-F17 HydrophobicContact CD2-CG 4.45Å; Y14-F17 AromaticContact CD2-CZ 3.35Å; Y14-F17 HydrophobicContact CD2-CZ 3.35Å; Y14-F17 AromaticContact CE2-CE2 3.92Å; Y14-F17 HydrophobicContact CE2-CE2 3.92Å; Y14-F17 HydrophobicContact CE2-CZ 4Å; Y14-F17 AromaticContact CG-CE1 3.93Å; Y14-F17 HydrophobicContact CG-CE1 3.93Å; Y14-F17 HydrophobicContact CG-CE2 4.21Å; Y14-F17 AromaticContact CG-CZ 3.75Å; Y14-F17 HydrophobicContact CG-CZ 3.75Å; Y14-F17 PolarHBondContact N-O 3.26Å; Y14-V19 HydrophobicContact CD2-CG2 3.86Å; Y14-V19 HydrophobicContact CE2-CB 4.1Å; Y14-V19 HydrophobicContact CE2-CG2 3.59Å; Y14-D53 PolarHBondContact OH-OD2 3.4Å; Y14-Q92 HydrophobicContact CD1-CB 4.2Å; Y14-Q92 HydrophobicContact CD1-CG 4.13Å; Y14-Q92 HydrophobicContact CG-CB 4.38Å; Y14-L95 HydrophobicContact CD1-CD1 3.99Å; Y14-L95 HydrophobicContact CE1-CD1 3.22Å; Y14-S97 PolarHBondContact OH-OG 3.37Å; Y14-S97 VanDerWaalsContact OH-OG 3.11Å
15E98.3Very high96.2Very high89 Ų8947.8 Ų47.842%0.41623%0.234SC..SBendtrans-58.6-37.8-176.5-174.6174.1157.300112T86 R88 A89E15-T86 VanDerWaalsContact CD-OG1 3.23Å; E15-T86 WeakPolarHBondContact OE1-CB 3.37Å; E15-T86 WeakPolarHBondContact OE1-CG2 3.22Å; E15-T86 PolarHBondContact OE1-OG1 3.21Å; E15-T86 PolarHBondContact OE2-OG1 2.99Å; E15-R88 VanDerWaalsContact OE2-CB 3.22Å; E15-R88 WeakPolarHBondContact OE2-CB 3.39Å; E15-R88 WeakPolarHBondContact OE2-CD 3.17Å; E15-R88 WeakPolarHBondContact OE2-CG 3.43Å; E15-R88 IonicContact OE2-NE 3.98Å; E15-A89 HydrophobicContact CB-CB 4.45Å; E15-A89 HydrophobicContact CG-CB 4.43Å; E15-A89 PolarHBondContact OE2-N 3.5Å
16D98.4Very high96.2Very high17 Ų1746.7 Ų46.79%0.09123%0.231CC..SBendtrans-134.77.3-169.5-152.943000115.4Y14 R36 H83 A89Y14-D16 PolarHBondContact O-N 3.34Å; D16-R36 IonicContact OD1-CZ 2.73Å; D16-R36 IonicContact OD1-NH1 2.82Å; D16-R36 PolarHBondContact OD1-NH1 2.84Å; D16-R36 IonicContact OD1-NH2 2.88Å; D16-R36 PolarHBondContact OD1-NH2 2.84Å; D16-R36 IonicContact OD2-NH1 3.02Å; D16-H83 PolarHBondContact O-CE1 2.93Å; D16-H83 VanDerWaalsContact O-CE1 3.22Å; D16-H83 PolarHBondContact O-ND1 3.33Å; D16-H83 IonicContact OD2-CE1 3.14Å; D16-H83 IonicContact OD2-CG 3.86Å; D16-H83 IonicContact OD2-ND1 2.65Å; D16-H83 PolarHBondContact OD2-ND1 2.91Å; D16-A89 HydrophobicContact CB-CB 4Å
17F98.8Very high96.2Very high6 Ų646.2 Ų46.23%0.02623%0.228CC..EExtended strand (participates in β ladder)trans-156.9164.117567.3-75.1000111.6Y14 V19 M29 E30 A78 Q92 T93 N98Y14-F17 WeakPolarHBondContact CB-O 3.09Å; Y14-F17 HydrophobicContact CD2-CD1 4.46Å; Y14-F17 AromaticContact CD2-CD2 3.94Å; Y14-F17 HydrophobicContact CD2-CD2 3.94Å; Y14-F17 AromaticContact CD2-CE1 3.94Å; Y14-F17 HydrophobicContact CD2-CE1 3.94Å; Y14-F17 AromaticContact CD2-CE2 3.38Å; Y14-F17 HydrophobicContact CD2-CE2 3.38Å; Y14-F17 HydrophobicContact CD2-CG 4.45Å; Y14-F17 AromaticContact CD2-CZ 3.35Å; Y14-F17 HydrophobicContact CD2-CZ 3.35Å; Y14-F17 AromaticContact CE2-CE2 3.92Å; Y14-F17 HydrophobicContact CE2-CE2 3.92Å; Y14-F17 HydrophobicContact CE2-CZ 4Å; Y14-F17 AromaticContact CG-CE1 3.93Å; Y14-F17 HydrophobicContact CG-CE1 3.93Å; Y14-F17 HydrophobicContact CG-CE2 4.21Å; Y14-F17 AromaticContact CG-CZ 3.75Å; Y14-F17 HydrophobicContact CG-CZ 3.75Å; Y14-F17 PolarHBondContact N-O 3.26Å; F17-V19 HydrophobicContact CD2-CG2 3.58Å; F17-V19 HydrophobicContact CE2-CG2 3.35Å; F17-M29 WeakPolarHBondContact CA-O 3.39Å; F17-E30 HydrophobicContact CB-CG 4.26Å; F17-A78 HydrophobicContact CB-CB 4.3Å; F17-A78 HydrophobicContact CD2-CB 3.6Å; F17-A78 HydrophobicContact CE2-CB 3.98Å; F17-A78 HydrophobicContact CG-CB 3.92Å; F17-Q92 HydrophobicContact CE1-CB 3.96Å; F17-Q92 HydrophobicContact CZ-CB 4.39Å; F17-T93 HydrophobicContact CE1-CG2 4.08Å; F17-N98 HydrophobicContact CE2-CB 4.3Å
18V98.6Very high96.4Very high15 Ų1545.3 Ų45.39%0.09122%0.219CC..EExtended strand (participates in β ladder)trans-119.4143177.7-179.10000109.4M1 Y5 L11 R12 T13 W27 V28 M29M1-V18 HydrophobicContact CG-CG2 3.91Å; M1-V18 HydrophobicContact SD-CB 3.93Å; M1-V18 HydrophobicContact SD-CG1 4.22Å; M1-V18 HydrophobicContact SD-CG2 3.9Å; Y5-V18 HydrophobicContact CE1-CG1 4.35Å; L11-V18 HydrophobicContact CD2-CG1 4.45Å; R12-V18 WeakPolarHBondContact O-CA 3.48Å; T13-V18 HydrophobicContact CG2-CG2 4.3Å; V18-W27 HydrophobicContact CB-CZ3 4.43Å; V18-W27 HydrophobicContact CG1-CH2 4.06Å; V18-W27 HydrophobicContact CG1-CZ3 4.05Å; V18-V28 CarbonylContact O-C 3.58Å; V18-V28 WeakPolarHBondContact O-CA 3.42Å; V18-M29 HydrophobicContact CB-CB 4.46Å; V18-M29 PolarHBondContact N-O 2.82Å; V18-M29 PolarHBondContact O-N 2.73Å
19V98.6Very high96.4Very high1 Ų138.5 Ų38.51%0.00619%0.189CC..EExtended strand (participates in β ladder)trans-126.9142.5179.3-179.20000110.2L11 R12 Y14 F17 A25 V28L11-V19 CarbonylContact C-O 3.58Å; L11-V19 WeakPolarHBondContact CA-O 3.28Å; R12-V19 PolarHBondContact N-O 3.37Å; R12-V19 PolarHBondContact O-N 2.95Å; Y14-V19 HydrophobicContact CD2-CG2 3.86Å; Y14-V19 HydrophobicContact CE2-CB 4.1Å; Y14-V19 HydrophobicContact CE2-CG2 3.59Å; F17-V19 HydrophobicContact CD2-CG2 3.58Å; F17-V19 HydrophobicContact CE2-CG2 3.35Å; V19-A25 HydrophobicContact CG1-CB 3.73Å; V19-V28 HydrophobicContact CB-CG1 4.39Å; V19-V28 HydrophobicContact CG1-CG1 4.24Å; V19-V28 HydrophobicContact CG2-CB 4.41Å; V19-V28 HydrophobicContact CG2-CG1 3.78Å
20S98.5Very high96.6Very high2 Ų234.8 Ų34.81%0.01417%0.169CC..EExtended strand (participates in β ladder)trans-113.9133.5163.8170.50000108.3D9 A25 H26 W27D9-S20 PolarHBondContact O-OG 2.79Å; S20-A25 CarbonylContact O-C 3.58Å; S20-A25 WeakPolarHBondContact O-CA 3.11Å; S20-A25 WeakPolarHBondContact O-CB 3.38Å; S20-H26 PolarHBondContact O-N 3.17Å; S20-H26 PolarHBondContact OG-CD2 3.26Å; S20-W27 VanDerWaalsContact CB-CZ2 3.46Å; S20-W27 PolarHBondContact N-O 2.73Å
21Y97.3Very high96.7Very high7 Ų733.2 Ų33.23%0.02716%0.159CC..EExtended strand (participates in β ladder)trans-126136.9-161.3-171.9-101.6000116.3D9 N10 R23 T24 I56 F60D9-Y21 PolarHBondContact O-N 3.14Å; N10-Y21 WeakPolarHBondContact CB-O 3.23Å; N10-Y21 PolarHBondContact ND2-O 2.86Å; Y21-R23 VanDerWaalsContact CE1-N 3.32Å; Y21-R23 VanDerWaalsContact CE2-C 3.47Å; Y21-R23 WeakPolarHBondContact CE2-O 3.49Å; Y21-R23 VanDerWaalsContact OH-CA 3.28Å; Y21-R23 WeakPolarHBondContact OH-CA 3.33Å; Y21-R23 PolarHBondContact OH-O 3.01Å; Y21-T24 WeakPolarHBondContact CD2-O 3.44Å; Y21-I56 HydrophobicContact CD1-CD1 3.6Å; Y21-I56 HydrophobicContact CD1-CG1 4.03Å; Y21-I56 HydrophobicContact CD1-CG2 4.23Å; Y21-I56 HydrophobicContact CD2-CD1 3.99Å; Y21-I56 HydrophobicContact CE1-CB 4.46Å; Y21-I56 HydrophobicContact CE1-CD1 3.42Å; Y21-I56 VanDerWaalsContact CE1-CD1 3.42Å; Y21-I56 HydrophobicContact CE1-CG1 4.03Å; Y21-I56 HydrophobicContact CE1-CG2 3.66Å; Y21-I56 HydrophobicContact CE2-CD1 3.85Å; Y21-I56 HydrophobicContact CG-CD1 3.85Å; Y21-F60 WeakPolarHBondContact CE1-O 3.21Å; Y21-F60 PolarHBondContact OH-O 3.21Å
22D90.2Very high96.8Very high67 Ų6731 Ų3136%0.35815%0.147SC..SBendtrans-150.180.6169.3175.122.9000111.7T24 H26D22-T24 CarbonylContact C-O 3.51Å; D22-T24 WeakPolarHBondContact CA-O 3.46Å; D22-T24 PolarHBondContact N-O 3.04Å; D22-T24 PolarHBondContact O-N 2.6Å; D22-H26 WeakPolarHBondContact CB-CE1 3.35Å; D22-H26 VanDerWaalsContact CB-NE2 3.34Å; D22-H26 WeakPolarHBondContact CB-NE2 3.18Å; D22-H26 IonicContact OD2-CE1 3.54Å
23R82.8Confident96.8Very high110 Ų11028.2 Ų28.242%0.41514%0.139SC..SBendtrans59.4-34.4-173.1-6586.4170.5-164.2-1.9115.4Y21Y21-R23 VanDerWaalsContact CE1-N 3.32Å; Y21-R23 VanDerWaalsContact CE2-C 3.47Å; Y21-R23 WeakPolarHBondContact CE2-O 3.49Å; Y21-R23 VanDerWaalsContact OH-CA 3.28Å; Y21-R23 WeakPolarHBondContact OH-CA 3.33Å; Y21-R23 PolarHBondContact OH-O 3.01Å
24T90.9Very high96.8Very high4 Ų425.7 Ų25.73%0.02512%0.124CC..SBendtrans-118.5169.9155173.10000107.5Y21 D22 M99 A100 P135 Y137Y21-T24 WeakPolarHBondContact CD2-O 3.44Å; D22-T24 CarbonylContact C-O 3.51Å; D22-T24 WeakPolarHBondContact CA-O 3.46Å; D22-T24 PolarHBondContact N-O 3.04Å; D22-T24 PolarHBondContact O-N 2.6Å; T24-M99 PolarHBondContact OG1-O 3.06Å; T24-A100 WeakPolarHBondContact OG1-CB 3.42Å; T24-P135 HydrophobicContact CG2-CG 4.41Å; T24-Y137 WeakPolarHBondContact CG2-OH 3.44Å
25A94.8Very high96.7Very high1 Ų128.6 Ų28.61%0.00814%0.142CC..EExtended strand (participates in β ladder)trans-67.9142.1172.500000111.7V19 S20 V28 L77 P135V19-A25 HydrophobicContact CG1-CB 3.73Å; S20-A25 CarbonylContact O-C 3.58Å; S20-A25 WeakPolarHBondContact O-CA 3.11Å; S20-A25 WeakPolarHBondContact O-CB 3.38Å; A25-V28 HydrophobicContact CB-CG1 3.94Å; A25-L77 HydrophobicContact CB-CD1 3.45Å; A25-L77 VanDerWaalsContact CB-CD1 3.45Å; A25-P135 WeakPolarHBondContact O-CD 3.46Å; A25-P135 WeakPolarHBondContact O-CG 3.19Å
26H97.5Very high96.6Very high53 Ų5327.7 Ų27.725%0.24514%0.135CC..EExtended strand (participates in β ladder)trans-64.2-45.6159.8-71.8-58.8000110.4D9 S20 D22 P135D9-H26 IonicContact OD2-CD2 3.48Å; D9-H26 IonicContact OD2-CE1 3.44Å; D9-H26 IonicContact OD2-NE2 3.57Å; D9-H26 PolarHBondContact OD2-NE2 3.19Å; S20-H26 PolarHBondContact O-N 3.17Å; S20-H26 PolarHBondContact OG-CD2 3.26Å; D22-H26 WeakPolarHBondContact CB-CE1 3.35Å; D22-H26 VanDerWaalsContact CB-NE2 3.34Å; D22-H26 WeakPolarHBondContact CB-NE2 3.18Å; D22-H26 IonicContact OD2-CE1 3.54Å; H26-P135 WeakPolarHBondContact O-CD 3.34Å
27W98.6Very high96.5Very high1 Ų127.3 Ų27.30%0.00413%0.132CC..EExtended strand (participates in β ladder)trans-161.8159.9176.154.3-96000110.1M1 Y5 P6 G7 L11 V18 S20 M29 T133 F166 F212M1-W27 HydrophobicContact CE-CH2 3.7Å; M1-W27 HydrophobicContact CE-CZ3 3.89Å; Y5-W27 HydrophobicContact CD1-CH2 4Å; Y5-W27 HydrophobicContact CD1-CZ2 4.44Å; P6-W27 HydrophobicContact CB-CD2 4.15Å; P6-W27 HydrophobicContact CB-CG 4.18Å; P6-W27 HydrophobicContact CB-CZ2 4.5Å; P6-W27 HydrophobicContact CG-CD2 3.81Å; P6-W27 HydrophobicContact CG-CE3 4.17Å; P6-W27 HydrophobicContact CG-CG 4.16Å; P6-W27 HydrophobicContact CG-CZ2 4.3Å; G7-W27 VanDerWaalsContact O-CZ2 3.31Å; G7-W27 WeakPolarHBondContact O-CZ2 3.28Å; L11-W27 HydrophobicContact CD2-CH2 3.56Å; L11-W27 HydrophobicContact CD2-CZ2 3.59Å; V18-W27 HydrophobicContact CB-CZ3 4.43Å; V18-W27 HydrophobicContact CG1-CH2 4.06Å; V18-W27 HydrophobicContact CG1-CZ3 4.05Å; S20-W27 VanDerWaalsContact CB-CZ2 3.46Å; S20-W27 PolarHBondContact N-O 2.73Å; W27-M29 HydrophobicContact CE3-CB 4.13Å; W27-M29 HydrophobicContact CZ3-CB 3.82Å; W27-T133 CarbonylContact C-O 3.58Å; W27-T133 VanDerWaalsContact CA-O 3.25Å; W27-T133 WeakPolarHBondContact CA-O 3.35Å; W27-F166 HydrophobicContact CB-CZ 4.34Å; W27-F212 HydrophobicContact CB-CE2 4.36Å; W27-F212 HydrophobicContact CB-CZ 3.92Å; W27-F212 AromaticContact CD1-CE1 3.72Å; W27-F212 AromaticContact CD1-CZ 3.75Å; W27-F212 HydrophobicContact CG-CE2 4.49Å; W27-F212 HydrophobicContact CG-CZ 4.18Å
28V98.8Very high96.4Very high0 Ų032.1 Ų32.10%016%0.157CC..EExtended strand (participates in β ladder)trans-124.8148.9166.7-51.60000109.6V18 V19 A25 L77 A78 C132 T133V18-V28 CarbonylContact O-C 3.58Å; V18-V28 WeakPolarHBondContact O-CA 3.42Å; V19-V28 HydrophobicContact CB-CG1 4.39Å; V19-V28 HydrophobicContact CG1-CG1 4.24Å; V19-V28 HydrophobicContact CG2-CB 4.41Å; V19-V28 HydrophobicContact CG2-CG1 3.78Å; A25-V28 HydrophobicContact CB-CG1 3.94Å; V28-L77 HydrophobicContact CB-CB 4.42Å; V28-L77 HydrophobicContact CG1-CB 3.76Å; V28-L77 HydrophobicContact CG1-CD1 4.17Å; V28-L77 HydrophobicContact CG2-CB 3.69Å; V28-A78 HydrophobicContact CB-CB 4.32Å; V28-A78 HydrophobicContact CG2-CB 3.97Å; V28-C132 WeakPolarHBondContact O-CA 3.31Å; V28-T133 PolarHBondContact N-O 3.4Å; V28-T133 PolarHBondContact O-N 2.88Å
29M98.8Very high96.1Very high9 Ų935.7 Ų35.74%0.04417%0.17CC..EExtended strand (participates in β ladder)trans-124.8127.1179.1-163.272.868.500110.6M1 P6 F17 V18 W27 V131 C132 F215M1-M29 HydrophobicContact CE-CB 4.22Å; M1-M29 HydrophobicContact CE-CE 4.41Å; M1-M29 HydrophobicContact CE-CG 4.27Å; M1-M29 HydrophobicContact SD-CB 3.57Å; M1-M29 VanDerWaalsContact SD-CB 3.57Å; M1-M29 HydrophobicContact SD-CG 3.56Å; M1-M29 VanDerWaalsContact SD-CG 3.56Å; P6-M29 HydrophobicContact CG-CE 3.42Å; P6-M29 VanDerWaalsContact CG-CE 3.42Å; F17-M29 WeakPolarHBondContact CA-O 3.39Å; V18-M29 HydrophobicContact CB-CB 4.46Å; V18-M29 PolarHBondContact N-O 2.82Å; V18-M29 PolarHBondContact O-N 2.73Å; W27-M29 HydrophobicContact CE3-CB 4.13Å; W27-M29 HydrophobicContact CZ3-CB 3.82Å; M29-V131 CarbonylContact C-O 3.04Å; M29-V131 WeakPolarHBondContact CA-O 3.31Å; M29-C132 HydrophobicContact CE-CB 3.85Å; M29-C132 HydrophobicContact SD-CB 3.78Å; M29-F215 HydrophobicContact CE-CE1 4.22Å; M29-F215 HydrophobicContact SD-CE1 3.66Å; M29-F215 HydrophobicContact SD-CZ 4.24Å
30E98.9Very high96Very high3 Ų337.1 Ų37.11%0.01418%0.18CC..EExtended strand (participates in β ladder)trans-120.6148.5-178.7-54.8167.682.300109.9F17 L32 A78 N82 H83 Y130 V131F17-E30 HydrophobicContact CB-CG 4.26Å; E30-L32 HydrophobicContact CB-CD2 4.16Å; E30-A78 HydrophobicContact CG-CB 4.07Å; E30-N82 WeakPolarHBondContact OE1-CB 3.41Å; E30-N82 PolarHBondContact OE1-ND2 3.08Å; E30-H83 IonicContact OE1-CE1 2.77Å; E30-H83 IonicContact OE1-NE2 3.76Å; E30-H83 PolarHBondContact OE1-NE2 3.37Å; E30-H83 VanDerWaalsContact OE1-NE2 3.09Å; E30-Y130 WeakPolarHBondContact O-CA 3.42Å; E30-V131 HydrophobicContact CB-CB 4.27Å; E30-V131 PolarHBondContact N-O 2.86Å; E30-V131 PolarHBondContact O-N 2.94Å
31H98.7Very high95.9Very high53 Ų5343.7 Ų43.725%0.24522%0.222CC..EExtended strand (participates in β ladder)trans-125.8112.7169.3172.4-142.6000109.5T33 R36 N128 Y130H31-T33 WeakPolarHBondContact NE2-CG2 3.4Å; H31-R36 WeakPolarHBondContact O-CD 3.39Å; H31-R36 PolarHBondContact O-NH1 3.11Å; H31-N128 PolarHBondContact NE2-OD1 3.34Å; H31-Y130 HydrophobicContact CB-CD1 4.1Å; H31-Y130 HydrophobicContact CB-CE1 4.17Å; H31-Y130 AromaticContact CD2-CD1 3.97Å; H31-Y130 AromaticContact CD2-CE1 3.62Å; H31-Y130 AromaticContact CD2-CZ 3.72Å; H31-Y130 AromaticContact CG-CE1 3.76Å; H31-Y130 AromaticContact NE2-CZ 3.84Å
32L98.7Very high95.8Very high0 Ų047.4 Ų47.40%025%0.249CC..EExtended strand (participates in β ladder)trans-110.5142.9-174.9-44.8-178.5000109.7E30 M37 N82 V119 A123 V129 V131E30-L32 HydrophobicContact CB-CD2 4.16Å; L32-M37 HydrophobicContact CB-CE 4.15Å; L32-M37 HydrophobicContact CD1-CE 4.48Å; L32-M37 HydrophobicContact CD2-CE 3.95Å; L32-M37 HydrophobicContact CG-CE 4.41Å; L32-N82 HydrophobicContact CD1-CB 4.44Å; L32-N82 HydrophobicContact CD2-CB 3.88Å; L32-V119 HydrophobicContact CD1-CG1 4.04Å; L32-A123 HydrophobicContact CB-CB 3.61Å; L32-A123 HydrophobicContact CD1-CB 4.11Å; L32-V129 HydrophobicContact CB-CB 4.34Å; L32-V129 PolarHBondContact N-O 3.22Å; L32-V129 PolarHBondContact O-N 2.89Å; L32-V131 HydrophobicContact CD1-CG2 4.04Å; L32-V131 HydrophobicContact CG-CG2 4.43Å
33T98.3Very high96.2Very high21 Ų2144.8 Ų44.813%0.12924%0.236CC..  trans-140164.3176.564.70000109.1H31 D35 R36 M37 A123 N128H31-T33 WeakPolarHBondContact NE2-CG2 3.4Å; T33-D35 VanDerWaalsContact C-N 3.26Å; T33-D35 PolarHBondContact O-N 2.9Å; T33-R36 PolarHBondContact O-N 2.89Å; T33-R36 VanDerWaalsContact O-N 3.11Å; T33-R36 WeakPolarHBondContact OG1-CG 3.4Å; T33-R36 PolarHBondContact OG1-N 2.61Å; T33-M37 WeakPolarHBondContact O-CG 3.17Å; T33-M37 PolarHBondContact O-N 3.38Å; T33-A123 CarbonylContact C-O 3.49Å; T33-N128 WeakPolarHBondContact CG2-OD1 3.38Å
34P97.9Very high96.9Very high54 Ų5442.4 Ų42.435%0.35123%0.231SC..THydrogen-bonded Turntrans-55.5-42.8176.3-27.736.4000112.1R36 M37 I38 A123 N126P34-R36 PolarHBondContact O-N 3.3Å; P34-M37 PolarHBondContact O-N 2.85Å; P34-M37 VanDerWaalsContact O-N 3.15Å; P34-I38 PolarHBondContact O-N 3.44Å; P34-A123 WeakPolarHBondContact CD-O 3.24Å; P34-A123 WeakPolarHBondContact CG-O 3.39Å; P34-N126 WeakPolarHBondContact CD-O 3.12Å; P34-N126 WeakPolarHBondContact CG-O 3.46Å
35D96.8Very high97.1Very high87 Ų8748.7 Ų48.747%0.46526%0.255SS..G310 helixtrans-61.9-42.4176.7173.265.7000112.5T33 M37 I38 K85T33-D35 VanDerWaalsContact C-N 3.26Å; T33-D35 PolarHBondContact O-N 2.9Å; D35-M37 PolarHBondContact O-N 3.03Å; D35-I38 WeakPolarHBondContact O-CB 3.38Å; D35-I38 PolarHBondContact O-N 2.88Å; D35-I38 VanDerWaalsContact O-N 3.12Å; D35-K85 WeakPolarHBondContact O-CE 3.27Å; D35-K85 PolarHBondContact O-NZ 2.81Å; D35-K85 IonicContact OD1-NZ 2.73Å; D35-K85 PolarHBondContact OD1-NZ 3.01Å; D35-K85 WeakPolarHBondContact OD2-CE 3.45Å; D35-K85 IonicContact OD2-NZ 3.1Å; D35-K85 PolarHBondContact OD2-NZ 2.86Å
36R96.4Very high97.2Very high71 Ų7153.4 Ų53.427%0.26829%0.287SS..G310 helixtrans-67.3-22.2177.1-71.9174.2166.8-127.7-21.1113.1D16 H31 T33 P34 I38D16-R36 IonicContact OD1-CZ 2.73Å; D16-R36 IonicContact OD1-NH1 2.82Å; D16-R36 PolarHBondContact OD1-NH1 2.84Å; D16-R36 IonicContact OD1-NH2 2.88Å; D16-R36 PolarHBondContact OD1-NH2 2.84Å; D16-R36 IonicContact OD2-NH1 3.02Å; H31-R36 WeakPolarHBondContact O-CD 3.39Å; H31-R36 PolarHBondContact O-NH1 3.11Å; T33-R36 PolarHBondContact O-N 2.89Å; T33-R36 VanDerWaalsContact O-N 3.11Å; T33-R36 WeakPolarHBondContact OG1-CG 3.4Å; T33-R36 PolarHBondContact OG1-N 2.61Å; P34-R36 PolarHBondContact O-N 3.3Å; R36-I38 VanDerWaalsContact C-N 3.32Å
37M96.9Very high97.2Very high8 Ų857.3 Ų57.34%0.03930%0.304CS..G310 helixtrans-83.8-5.2175.1-64.5-61.39500113.6L32 T33 P34 D35 Y39 N82 R120 A123 R124L32-M37 HydrophobicContact CB-CE 4.15Å; L32-M37 HydrophobicContact CD1-CE 4.48Å; L32-M37 HydrophobicContact CD2-CE 3.95Å; L32-M37 HydrophobicContact CG-CE 4.41Å; T33-M37 WeakPolarHBondContact O-CG 3.17Å; T33-M37 PolarHBondContact O-N 3.38Å; P34-M37 PolarHBondContact O-N 2.85Å; P34-M37 VanDerWaalsContact O-N 3.15Å; D35-M37 PolarHBondContact O-N 3.03Å; M37-Y39 WeakPolarHBondContact O-CD1 3.26Å; M37-Y39 WeakPolarHBondContact O-CE1 3.26Å; M37-Y39 PolarHBondContact O-N 2.85Å; M37-N82 WeakPolarHBondContact CE-O 3.24Å; M37-R120 HydrophobicContact SD-CB 4.27Å; M37-R120 HydrophobicContact SD-CG 3.93Å; M37-A123 HydrophobicContact CG-CB 3.76Å; M37-A123 HydrophobicContact SD-CB 4.07Å; M37-R124 HydrophobicContact CB-CG 3.71Å; M37-R124 HydrophobicContact CG-CG 4Å
38I96.2Very high97.2Very high108 Ų10858 Ų5855%0.55431%0.308SS*.SBendtrans-80.7114.4169.6-58.2172000107.9P34 D35 R36P34-I38 PolarHBondContact O-N 3.44Å; D35-I38 WeakPolarHBondContact O-CB 3.38Å; D35-I38 PolarHBondContact O-N 2.88Å; D35-I38 VanDerWaalsContact O-N 3.12Å; R36-I38 VanDerWaalsContact C-N 3.32Å
39Y93.3Very high97.2Very high89 Ų8965 Ų6535%0.34934%0.341SS..  trans-75.1131.2-176.4-59.8-14.4000110.8M37 R84M37-Y39 WeakPolarHBondContact O-CD1 3.26Å; M37-Y39 WeakPolarHBondContact O-CE1 3.26Å; M37-Y39 PolarHBondContact O-N 2.85Å; Y39-R84 HydrophobicContact CD1-CB 3.75Å; Y39-R84 HydrophobicContact CD1-CG 4.19Å; Y39-R84 HydrophobicContact CE1-CB 4.29Å; Y39-R84 HydrophobicContact CE1-CG 4.28Å; Y39-R84 HydrophobicContact CG-CB 4.21Å
40S95.5Very high97.2Very high32 Ų3267.2 Ų67.222%0.22435%0.351CS..  trans-76129.6171.9175.60000109.8S42 V43 R84 K85S40-S42 PolarHBondContact O-N 2.84Å; S40-S42 PolarHBondContact OG-OG 2.86Å; S40-V43 WeakPolarHBondContact O-CB 3.49Å; S40-V43 PolarHBondContact O-N 2.8Å; S40-R84 PolarHBondContact N-O 2.79Å; S40-R84 VanDerWaalsContact N-O 3.07Å; S40-K85 WeakPolarHBondContact CB-O 3.37Å
41P95.7Very high97.2Very high139 Ų13973 Ų7390%0.90337%0.372SS*.THydrogen-bonded Turntrans-65.7-17.4179.827.1-34.6000112.9V43P41-V43 PolarHBondContact O-N 2.49Å
42S95.8Very high97.1Very high85 Ų8572.8 Ų72.859%0.59437%0.372SS*.THydrogen-bonded Turntrans-73.7-11.7173.865.30000114S40S40-S42 PolarHBondContact O-N 2.84Å; S40-S42 PolarHBondContact OG-OG 2.86Å
43V97.9Very high97.1Very high12 Ų1273.3 Ų73.37%0.07337%0.374CS..  trans-94.9116.7-175.1179.50000110.9S40 P41 R84 T86 V90S40-V43 WeakPolarHBondContact O-CB 3.49Å; S40-V43 PolarHBondContact O-N 2.8Å; P41-V43 PolarHBondContact O-N 2.49Å; V43-R84 HydrophobicContact CG1-CB 4.34Å; V43-T86 VanDerWaalsContact CG2-C 3.42Å; V43-V90 HydrophobicContact CG1-CB 4.19Å; V43-V90 HydrophobicContact CG1-CG1 3.47Å; V43-V90 VanDerWaalsContact CG1-CG1 3.47Å
44D97.6Very high97.1Very high61 Ų6178.7 Ų78.733%0.32640%0.398SS..  trans-119.6109.9179.9-175.3-1000110.9S46 K47 Q87D44-S46 PolarHBondContact O-N 3.02Å; D44-S46 WeakPolarHBondContact OD1-CB 3.25Å; D44-S46 PolarHBondContact OD1-N 3.03Å; D44-S46 PolarHBondContact OD1-OG 2.98Å; D44-S46 PolarHBondContact OD2-OG 2.75Å; D44-K47 HydrophobicContact CB-CD 4.03Å; D44-K47 HydrophobicContact CB-CG 4.12Å; D44-K47 PolarHBondContact O-N 3.26Å; D44-K47 WeakPolarHBondContact OD2-CE 3.41Å; D44-Q87 PolarHBondContact O-NE2 3.06Å; D44-Q87 VanDerWaalsContact O-NE2 3.08Å; D44-Q87 PolarHBondContact O-OE1 3.41Å
45R96.9Very high97Very high136 Ų13678.8 Ų78.851%0.51340%0.4SS..G310 helixtrans-66.7-25.4179.2-178178.2168.4-133.8-2.4112.1K47 C48 F94R45-K47 PolarHBondContact O-N 2.81Å; R45-C48 VanDerWaalsContact O-CB 3.29Å; R45-C48 WeakPolarHBondContact O-CB 3.19Å; R45-C48 PolarHBondContact O-N 2.77Å; R45-C48 VanDerWaalsContact O-N 3.08Å; R45-F94 HydrophobicContact CG-CE2 4.19Å; R45-F94 HydrophobicContact CG-CZ 3.92Å
46S96.9Very high97.1Very high99 Ų9975.1 Ų75.169%0.69238%0.38SS*.G310 helixtrans-67.3-20.2-179.473.20000112.9D44 C48D44-S46 PolarHBondContact O-N 3.02Å; D44-S46 WeakPolarHBondContact OD1-CB 3.25Å; D44-S46 PolarHBondContact OD1-N 3.03Å; D44-S46 PolarHBondContact OD1-OG 2.98Å; D44-S46 PolarHBondContact OD2-OG 2.75Å; S46-C48 VanDerWaalsContact C-N 3.29Å
47K97.7Very high97.1Very high135 Ų13577 Ų7759%0.58739%0.392SS*.G310 helixtrans-81.1-6.9174-58.4-179.2-176.2176.10113.6D44 R45D44-K47 HydrophobicContact CB-CD 4.03Å; D44-K47 HydrophobicContact CB-CG 4.12Å; D44-K47 PolarHBondContact O-N 3.26Å; D44-K47 WeakPolarHBondContact OD2-CE 3.41Å; R45-K47 PolarHBondContact O-N 2.81Å
48C98.3Very high97.1Very high15 Ų1578.7 Ų78.710%0.10141%0.407CS..  trans-81.9134-178.9-60.20000110.8R45 S46 F94R45-C48 VanDerWaalsContact O-CB 3.29Å; R45-C48 WeakPolarHBondContact O-CB 3.19Å; R45-C48 PolarHBondContact O-N 2.77Å; R45-C48 VanDerWaalsContact O-N 3.08Å; S46-C48 VanDerWaalsContact C-N 3.29Å; C48-F94 HydrophobicContact CB-CD1 3.97Å; C48-F94 HydrophobicContact CB-CD2 3.42Å; C48-F94 VanDerWaalsContact CB-CD2 3.42Å; C48-F94 HydrophobicContact CB-CE1 3.9Å; C48-F94 HydrophobicContact CB-CE2 3.35Å; C48-F94 HydrophobicContact CB-CG 3.72Å; C48-F94 HydrophobicContact CB-CZ 3.59Å
49E98.3Very high97.2Very high149 Ų14981.1 Ų81.170%0.69641%0.414SS*.  trans-117.8134.4177.9-64.5-177.3172.500110.6R51 F94E49-R51 PolarHBondContact O-N 2.65Å; E49-R51 VanDerWaalsContact O-N 3.14Å; E49-F94 WeakPolarHBondContact O-CB 3.41Å
50F98.7Very high97.4Very high54 Ų5481.2 Ų81.224%0.23742%0.416CS..  trans-63116.3167.7-70.6-78.4000109N64 R74 H76 F94 L96 M99F50-N64 WeakPolarHBondContact CB-OD1 3.37Å; F50-N64 PolarHBondContact O-ND2 3.11Å; F50-R74 HydrophobicContact CD1-CB 3.87Å; F50-R74 HydrophobicContact CD1-CG 4.41Å; F50-R74 VanDerWaalsContact CD2-CZ 3.48Å; F50-R74 HydrophobicContact CE1-CB 3.55Å; F50-R74 HydrophobicContact CZ-CB 4.03Å; F50-H76 AromaticContact CE1-CE1 3.47Å; F50-H76 VanDerWaalsContact CE1-CE1 3.47Å; F50-H76 WeakPolarHBondContact CE1-CE1 3.38Å; F50-H76 AromaticContact CZ-CE1 3.71Å; F50-F94 WeakPolarHBondContact CA-O 3.37Å; F50-F94 AromaticContact CD1-CD1 3.95Å; F50-F94 HydrophobicContact CD1-CD1 3.95Å; F50-F94 HydrophobicContact CD2-CD1 4.09Å; F50-F94 HydrophobicContact CD2-CE1 4.44Å; F50-F94 AromaticContact CE1-CD1 3.91Å; F50-F94 HydrophobicContact CE1-CD1 3.91Å; F50-F94 HydrophobicContact CE1-CE1 4.38Å; F50-F94 HydrophobicContact CE2-CD1 4.05Å; F50-F94 HydrophobicContact CE2-CE1 4.04Å; F50-F94 HydrophobicContact CG-CD1 4.05Å; F50-F94 AromaticContact CZ-CD1 3.97Å; F50-F94 HydrophobicContact CZ-CD1 3.97Å; F50-F94 HydrophobicContact CZ-CE1 4.02Å; F50-L96 HydrophobicContact CB-CD2 4.38Å; F50-L96 HydrophobicContact CD1-CD2 4.43Å; F50-M99 HydrophobicContact CD1-CE 4.39Å; F50-M99 HydrophobicContact CD1-CG 4.46Å; F50-M99 HydrophobicContact CD1-SD 4.12Å; F50-M99 HydrophobicContact CE1-CE 4.11Å; F50-M99 HydrophobicContact CE1-SD 3.67Å
51R98.2Very high97.5Very high124 Ų12481 Ų8147%0.46841%0.411SS..BIsolated β-bridgetrans-141.2154-17767.6-177.9176.6167.8-6.2111.8E49 F94 L95 L96E49-R51 PolarHBondContact O-N 2.65Å; E49-R51 VanDerWaalsContact O-N 3.14Å; R51-F94 PolarHBondContact N-O 2.77Å; R51-L95 HydrophobicContact CG-CD2 3.92Å; R51-L95 CarbonylContact O-C 3.6Å; R51-L95 WeakPolarHBondContact O-CA 3.42Å; R51-L96 WeakPolarHBondContact O-CG 3.12Å; R51-L96 PolarHBondContact O-N 3.48Å
52E98.1Very high97.6Very high50 Ų5074.5 Ų74.523%0.23437%0.368CS..  trans-64.8144.2177.5-48.9179.8-174.900111.1Q54 R61 R63 L96E52-Q54 PolarHBondContact O-N 3.31Å; E52-R61 HydrophobicContact CB-CG 4.3Å; E52-R61 VanDerWaalsContact OE2-CD 3.31Å; E52-R61 WeakPolarHBondContact OE2-CD 3.25Å; E52-R61 IonicContact OE2-NH1 3.09Å; E52-R61 PolarHBondContact OE2-NH1 3.43Å; E52-R61 VanDerWaalsContact OE2-NH1 3.08Å; E52-R63 HydrophobicContact CG-CG 4.32Å; E52-R63 VanDerWaalsContact OE1-CD 3.28Å; E52-R63 WeakPolarHBondContact OE1-CD 3.22Å; E52-R63 VanDerWaalsContact OE1-CG 3.26Å; E52-R63 WeakPolarHBondContact OE1-CG 3.32Å; E52-R63 IonicContact OE1-NE 2.68Å; E52-L96 HydrophobicContact CG-CD1 4.24Å
53D98.2Very high97.7Very high11 Ų1175.2 Ų75.26%0.05936%0.358CS..  trans-84.4107.7169.6174.311.1000109.8Y14 S55 I56 R61 L95Y14-D53 PolarHBondContact OH-OD2 3.4Å; D53-S55 PolarHBondContact O-N 3.47Å; D53-S55 WeakPolarHBondContact OD1-CB 3.42Å; D53-S55 PolarHBondContact OD1-N 3.38Å; D53-S55 PolarHBondContact OD1-OG 3.07Å; D53-S55 PolarHBondContact OD2-OG 3.24Å; D53-I56 HydrophobicContact CB-CD1 4.01Å; D53-I56 PolarHBondContact O-N 3.48Å; D53-I56 WeakPolarHBondContact OD2-CD1 3.22Å; D53-R61 WeakPolarHBondContact O-CD 3.38Å; D53-R61 PolarHBondContact O-NE 3.11Å; D53-L95 HydrophobicContact CB-CB 4.33Å; D53-L95 HydrophobicContact CB-CD1 4.49Å; D53-L95 HydrophobicContact CB-CD2 4.18Å
54Q97.7Very high97.8Very high133 Ų13377.1 Ų77.162%0.62137%0.368SS*.THydrogen-bonded Turntrans-68.4-15.1-178.3-61.5-61.2-3200113E52 I56 R61E52-Q54 PolarHBondContact O-N 3.31Å; Q54-I56 PolarHBondContact O-N 3.47Å; Q54-R61 VanDerWaalsContact CD-NH1 3.33Å; Q54-R61 PolarHBondContact O-NH2 2.95Å; Q54-R61 VanDerWaalsContact OE1-CZ 3.29Å
55S96.9Very high97.8Very high56 Ų5677.6 Ų77.639%0.39238%0.38SS..THydrogen-bonded Turntrans-74.4-11.7175.483.50000113.3R12 D53R12-S55 WeakPolarHBondContact CD-OG 3.26Å; R12-S55 PolarHBondContact NE-OG 3.39Å; R12-S55 PolarHBondContact NH2-O 3.3Å; D53-S55 PolarHBondContact O-N 3.47Å; D53-S55 WeakPolarHBondContact OD1-CB 3.42Å; D53-S55 PolarHBondContact OD1-N 3.38Å; D53-S55 PolarHBondContact OD1-OG 3.07Å; D53-S55 PolarHBondContact OD2-OG 3.24Å
56I97.3Very high97.9Very high10 Ų1071.4 Ų71.45%0.05136%0.357CS..SBendtrans-94.3132.7174.5-66.2161.5000108.9Y21 D53 Q54 F60 R61Y21-I56 HydrophobicContact CD1-CD1 3.6Å; Y21-I56 HydrophobicContact CD1-CG1 4.03Å; Y21-I56 HydrophobicContact CD1-CG2 4.23Å; Y21-I56 HydrophobicContact CD2-CD1 3.99Å; Y21-I56 HydrophobicContact CE1-CB 4.46Å; Y21-I56 HydrophobicContact CE1-CD1 3.42Å; Y21-I56 VanDerWaalsContact CE1-CD1 3.42Å; Y21-I56 HydrophobicContact CE1-CG1 4.03Å; Y21-I56 HydrophobicContact CE1-CG2 3.66Å; Y21-I56 HydrophobicContact CE2-CD1 3.85Å; Y21-I56 HydrophobicContact CG-CD1 3.85Å; D53-I56 HydrophobicContact CB-CD1 4.01Å; D53-I56 PolarHBondContact O-N 3.48Å; D53-I56 WeakPolarHBondContact OD2-CD1 3.22Å; Q54-I56 PolarHBondContact O-N 3.47Å; I56-F60 HydrophobicContact CG2-CB 4Å; I56-R61 HydrophobicContact CB-CG 4.42Å; I56-R61 HydrophobicContact CG2-CB 4.12Å; I56-R61 HydrophobicContact CG2-CG 4.43Å; I56-R61 PolarHBondContact O-NE 3.12Å; I56-R61 PolarHBondContact O-NH2 3.3Å
57H97.8Very high98Very high111 Ų11167.1 Ų67.151%0.51433%0.326SS..  trans-55.7140.2175.6-173.5-92.7000110.9F59 F60 R61H57-F59 AromaticContact CE1-CD1 3.7Å; H57-F59 AromaticContact CE1-CD2 3.59Å; H57-F59 AromaticContact CE1-CE1 3.99Å; H57-F59 AromaticContact CE1-CE2 3.9Å; H57-F59 AromaticContact CE1-CG 3.48Å; H57-F59 VanDerWaalsContact CE1-CG 3.48Å; H57-F59 WeakPolarHBondContact CE1-CG 3.43Å; H57-F59 AromaticContact ND1-CD2 3.8Å; H57-F59 AromaticContact ND1-CG 3.49Å; H57-F59 WeakPolarHBondContact ND1-CG 3.4Å; H57-F59 PolarHBondContact ND1-N 3.39Å; H57-F59 PolarHBondContact O-N 2.76Å; H57-F60 HydrophobicContact CB-CD2 4.03Å; H57-F60 HydrophobicContact CB-CE2 4.32Å; H57-F60 PolarHBondContact O-N 2.88Å; H57-R61 PolarHBondContact O-N 3.48Å
58A97.2Very high98Very high43 Ų4367 Ų6736%0.35533%0.329SS..G310 helixtrans-55.7-28.5-170.800000114.3F60A58-F60 VanDerWaalsContact C-N 3.28Å; A58-F60 PolarHBondContact O-N 3.39Å
59F97.1Very high98Very high160 Ų16074 Ų7470%0.70237%0.366SS*.G310 helixtrans-65.8-26.6177.3-67.7-4.5000114.4H57H57-F59 AromaticContact CE1-CD1 3.7Å; H57-F59 AromaticContact CE1-CD2 3.59Å; H57-F59 AromaticContact CE1-CE1 3.99Å; H57-F59 AromaticContact CE1-CE2 3.9Å; H57-F59 AromaticContact CE1-CG 3.48Å; H57-F59 VanDerWaalsContact CE1-CG 3.48Å; H57-F59 WeakPolarHBondContact CE1-CG 3.43Å; H57-F59 AromaticContact ND1-CD2 3.8Å; H57-F59 AromaticContact ND1-CG 3.49Å; H57-F59 WeakPolarHBondContact ND1-CG 3.4Å; H57-F59 PolarHBondContact ND1-N 3.39Å; H57-F59 PolarHBondContact O-N 2.76Å
60F97.7Very high98Very high91 Ų9168.2 Ų68.240%0.39934%0.341SS..G310 helixtrans-110.83.7-173.3-47.1-52.5000112.1Y21 I56 H57 A58Y21-F60 WeakPolarHBondContact CE1-O 3.21Å; Y21-F60 PolarHBondContact OH-O 3.21Å; I56-F60 HydrophobicContact CG2-CB 4Å; H57-F60 HydrophobicContact CB-CD2 4.03Å; H57-F60 HydrophobicContact CB-CE2 4.32Å; H57-F60 PolarHBondContact O-N 2.88Å; A58-F60 VanDerWaalsContact C-N 3.28Å; A58-F60 PolarHBondContact O-N 3.39Å
61R97.6Very high98Very high28 Ų2868.8 Ų68.811%0.10636%0.363CS..  trans-91.6121.9-169.1-160.5-172.3-54.4172.3-16.7111E52 D53 Q54 I56 H57E52-R61 HydrophobicContact CB-CG 4.3Å; E52-R61 VanDerWaalsContact OE2-CD 3.31Å; E52-R61 WeakPolarHBondContact OE2-CD 3.25Å; E52-R61 IonicContact OE2-NH1 3.09Å; E52-R61 PolarHBondContact OE2-NH1 3.43Å; E52-R61 VanDerWaalsContact OE2-NH1 3.08Å; D53-R61 WeakPolarHBondContact O-CD 3.38Å; D53-R61 PolarHBondContact O-NE 3.11Å; Q54-R61 VanDerWaalsContact CD-NH1 3.33Å; Q54-R61 PolarHBondContact O-NH2 2.95Å; Q54-R61 VanDerWaalsContact OE1-CZ 3.29Å; I56-R61 HydrophobicContact CB-CG 4.42Å; I56-R61 HydrophobicContact CG2-CB 4.12Å; I56-R61 HydrophobicContact CG2-CG 4.43Å; I56-R61 PolarHBondContact O-NE 3.12Å; I56-R61 PolarHBondContact O-NH2 3.3Å; H57-R61 PolarHBondContact O-N 3.48Å
62S98.2Very high98Very high2 Ų265 Ų651%0.01435%0.349CS..  trans-70.2147.1167.358.30000111.1L96S62-L96 WeakPolarHBondContact O-CD1 3.36Å; S62-L96 WeakPolarHBondContact OG-CB 3.43Å; S62-L96 PolarHBondContact OG-O 2.91Å
63R98.2Very high98Very high100 Ų10063.9 Ų63.938%0.37735%0.345SS..  trans-127.4157.9-178.3-55-169.3-176.9-167.2-1.5111.1E52 A65 D66 Y67 L96E52-R63 HydrophobicContact CG-CG 4.32Å; E52-R63 VanDerWaalsContact OE1-CD 3.28Å; E52-R63 WeakPolarHBondContact OE1-CD 3.22Å; E52-R63 VanDerWaalsContact OE1-CG 3.26Å; E52-R63 WeakPolarHBondContact OE1-CG 3.32Å; E52-R63 IonicContact OE1-NE 2.68Å; R63-A65 PolarHBondContact O-N 3.22Å; R63-A65 VanDerWaalsContact O-N 3.17Å; R63-D66 PolarHBondContact N-OD2 2.96Å; R63-D66 WeakPolarHBondContact O-CB 3.2Å; R63-D66 PolarHBondContact O-N 3.43Å; R63-Y67 WeakPolarHBondContact O-CD2 3.35Å; R63-L96 VanDerWaalsContact CA-CD1 3.46Å
64N98.5Very high98Very high51 Ų5167.5 Ų67.527%0.27336%0.358SS..Hα-helixtrans-57.5-33.2175.5-77.8-44.4000112.3F50 D66 Y67 M68 R74 L96F50-N64 WeakPolarHBondContact CB-OD1 3.37Å; F50-N64 PolarHBondContact O-ND2 3.11Å; N64-D66 PolarHBondContact O-N 3.09Å; N64-Y67 PolarHBondContact O-N 3.06Å; N64-M68 PolarHBondContact O-N 2.82Å; N64-R74 PolarHBondContact OD1-NH1 3.07Å; N64-L96 VanDerWaalsContact N-CD1 3.34Å
65A98.3Very high98.1Very high72 Ų7261.2 Ų61.260%0.59533%0.328SS*.Hα-helixtrans-62.7-25.4176.100000113.3R63R63-A65 PolarHBondContact O-N 3.22Å; R63-A65 VanDerWaalsContact O-N 3.17Å
66D98.6Very high98.2Very high5 Ų559.3 Ų59.33%0.02731%0.313CS..Hα-helixtrans-73.6-31.2177.1-57.9-53.9000112.1R63 N64 I154 G155 K156 N157 V159R63-D66 PolarHBondContact N-OD2 2.96Å; R63-D66 WeakPolarHBondContact O-CB 3.2Å; R63-D66 PolarHBondContact O-N 3.43Å; N64-D66 PolarHBondContact O-N 3.09Å; D66-I154 WeakPolarHBondContact O-CD1 3.26Å; D66-G155 WeakPolarHBondContact OD1-CA 3.34Å; D66-K156 PolarHBondContact OD1-N 2.83Å; D66-N157 VanDerWaalsContact CG-ND2 3.34Å; D66-N157 PolarHBondContact OD1-N 3.15Å; D66-N157 VanDerWaalsContact OD1-N 3.13Å; D66-N157 PolarHBondContact OD1-ND2 3.15Å; D66-N157 VanDerWaalsContact OD1-ND2 3.15Å; D66-N157 PolarHBondContact OD2-ND2 3.04Å; D66-V159 HydrophobicContact CB-CG2 3.97Å
67Y98.6Very high98.2Very high10 Ų1058.9 Ų58.94%0.03931%0.311CS..Hα-helixtrans-88.2-23.2178.9-67.6-94.6000112.8R63 N64 N69 S70 R74 L96 M99 P101 I154R63-Y67 WeakPolarHBondContact O-CD2 3.35Å; N64-Y67 PolarHBondContact O-N 3.06Å; Y67-N69 PolarHBondContact O-N 3.49Å; Y67-S70 WeakPolarHBondContact O-CB 3.34Å; Y67-S70 PolarHBondContact O-N 2.99Å; Y67-S70 PolarHBondContact O-OG 2.84Å; Y67-R74 HydrophobicContact CD1-CB 4.39Å; Y67-R74 HydrophobicContact CD1-CG 3.52Å; Y67-R74 HydrophobicContact CD2-CG 3.83Å; Y67-R74 HydrophobicContact CE1-CG 3.99Å; Y67-R74 HydrophobicContact CE2-CG 4.28Å; Y67-R74 HydrophobicContact CG-CG 3.42Å; Y67-R74 VanDerWaalsContact CG-CG 3.42Å; Y67-L96 HydrophobicContact CE2-CD2 4.34Å; Y67-M99 PolarHBondContact OH-O 3.39Å; Y67-P101 HydrophobicContact CE1-CB 4.25Å; Y67-P101 HydrophobicContact CE1-CG 3.83Å; Y67-I154 HydrophobicContact CD1-CD1 3.99Å; Y67-I154 HydrophobicContact CE1-CD1 4.31Å; Y67-I154 HydrophobicContact CG-CD1 4.33Å
68M98.3Very high98.3Very high131 Ų13153.6 Ų53.665%0.64529%0.286SS*.THydrogen-bonded Turntrans-60.5125.7-178.2-172.1179.2-65.600110.7N64 S70N64-M68 PolarHBondContact O-N 2.82Å; M68-S70 PolarHBondContact O-N 2.89Å
69N98Very high98.4Very high163 Ų16351.6 Ų51.687%0.87227%0.27SS*.THydrogen-bonded Turntrans55.618.1-177.7-58.2-31.4000115.2Y67 G71Y67-N69 PolarHBondContact O-N 3.49Å; N69-G71 VanDerWaalsContact C-N 3.26Å; N69-G71 PolarHBondContact O-N 2.93Å
70S98.4Very high98.4Very high27 Ų2744.3 Ų44.319%0.18924%0.239CC..SBendtrans-74.9-13.6177.966.20000113.9Y67 M68 Y72Y67-S70 WeakPolarHBondContact O-CB 3.34Å; Y67-S70 PolarHBondContact O-N 2.99Å; Y67-S70 PolarHBondContact O-OG 2.84Å; M68-S70 PolarHBondContact O-N 2.89Å; S70-Y72 WeakPolarHBondContact O-CD2 3.18Å; S70-Y72 WeakPolarHBondContact O-CE2 3.25Å; S70-Y72 PolarHBondContact O-N 2.79Å; S70-Y72 PolarHBondContact OG-N 3.32Å; S70-Y72 VanDerWaalsContact OG-N 3.14Å; S70-Y72 PolarHBondContact OG-O 3.01Å
71G98.4Very high98.4Very high67 Ų6740.8 Ų40.869%0.69123%0.229SC*.SBendtrans82.4-5.2-168.400000114.2N69N69-G71 VanDerWaalsContact C-N 3.26Å; N69-G71 PolarHBondContact O-N 2.93Å
72Y98.8Very high98.5Very high43 Ų4339.5 Ų39.517%0.16922%0.224CC..EExtended strand (participates in β ladder)trans-110.3147.5-179.7-59.2-81000112.7S70 P101 I103 E152 I154 V161S70-Y72 WeakPolarHBondContact O-CD2 3.18Å; S70-Y72 WeakPolarHBondContact O-CE2 3.25Å; S70-Y72 PolarHBondContact O-N 2.79Å; S70-Y72 PolarHBondContact OG-N 3.32Å; S70-Y72 VanDerWaalsContact OG-N 3.14Å; S70-Y72 PolarHBondContact OG-O 3.01Å; Y72-P101 HydrophobicContact CD1-CB 4.2Å; Y72-P101 HydrophobicContact CD2-CB 4.35Å; Y72-P101 HydrophobicContact CG-CB 3.85Å; Y72-I103 HydrophobicContact CD1-CD1 4.01Å; Y72-I103 HydrophobicContact CD1-CG1 4.45Å; Y72-I103 HydrophobicContact CE1-CD1 3.63Å; Y72-I103 HydrophobicContact CE1-CG1 4.19Å; Y72-E152 PolarHBondContact OH-OE2 3.13Å; Y72-I154 HydrophobicContact CD2-CD1 4.41Å; Y72-I154 HydrophobicContact CD2-CG2 3.97Å; Y72-I154 HydrophobicContact CE2-CG2 4Å; Y72-V161 HydrophobicContact CD1-CG1 4.07Å; Y72-V161 HydrophobicContact CD2-CG2 4.18Å; Y72-V161 HydrophobicContact CE1-CG1 3.46Å; Y72-V161 VanDerWaalsContact CE1-CG1 3.46Å; Y72-V161 HydrophobicContact CE1-CG2 4.46Å; Y72-V161 HydrophobicContact CE2-CG1 4.27Å; Y72-V161 HydrophobicContact CE2-CG2 3.8Å
73D98.8Very high98.5Very high28 Ų2839.4 Ų39.415%0.1522%0.223CC..EExtended strand (participates in β ladder)trans-78.2154.7165.9-77.3-10.4000111G75 Q102 G104 N108 R109D73-G75 VanDerWaalsContact C-N 3.26Å; D73-G75 PolarHBondContact O-N 3.49Å; D73-Q102 PolarHBondContact N-O 3.48Å; D73-Q102 PolarHBondContact O-N 3.36Å; D73-Q102 VanDerWaalsContact O-N 3.11Å; D73-G104 VanDerWaalsContact OD2-CA 3.25Å; D73-G104 WeakPolarHBondContact OD2-CA 3.49Å; D73-N108 HydrophobicContact CB-CB 4.45Å; D73-N108 VanDerWaalsContact CB-ND2 3.29Å; D73-N108 WeakPolarHBondContact CB-ND2 3.43Å; D73-N108 PolarHBondContact OD2-ND2 3.4Å; D73-R109 IonicContact OD1-CZ 2.91Å; D73-R109 IonicContact OD1-NE 2.73Å; D73-R109 PolarHBondContact OD1-NE 2.9Å; D73-R109 IonicContact OD1-NH2 3.08Å; D73-R109 PolarHBondContact OD1-NH2 3.4Å; D73-R109 WeakPolarHBondContact OD2-CG 3.27Å; D73-R109 IonicContact OD2-CZ 3.98Å; D73-R109 IonicContact OD2-NE 3.65Å; D73-R109 PolarHBondContact OD2-NE 3.31Å; D73-R109 IonicContact OD2-NH2 3.7Å
74R98.7Very high98.4Very high87 Ų8737.5 Ų37.533%0.32822%0.216SC..EExtended strand (participates in β ladder)trans-74.282.7160.7-70.3163-69.7-171.3-0.5108.5F50 N64 Y67 L96 M99F50-R74 HydrophobicContact CD1-CB 3.87Å; F50-R74 HydrophobicContact CD1-CG 4.41Å; F50-R74 VanDerWaalsContact CD2-CZ 3.48Å; F50-R74 HydrophobicContact CE1-CB 3.55Å; F50-R74 HydrophobicContact CZ-CB 4.03Å; N64-R74 PolarHBondContact OD1-NH1 3.07Å; Y67-R74 HydrophobicContact CD1-CB 4.39Å; Y67-R74 HydrophobicContact CD1-CG 3.52Å; Y67-R74 HydrophobicContact CD2-CG 3.83Å; Y67-R74 HydrophobicContact CE1-CG 3.99Å; Y67-R74 HydrophobicContact CE2-CG 4.28Å; Y67-R74 HydrophobicContact CG-CG 3.42Å; Y67-R74 VanDerWaalsContact CG-CG 3.42Å; R74-L96 HydrophobicContact CG-CD2 4.21Å; R74-M99 HydrophobicContact CB-CB 4.49Å; R74-M99 HydrophobicContact CB-CG 4.14Å; R74-M99 HydrophobicContact CB-SD 3.99Å; R74-M99 VanDerWaalsContact O-SD 3.41Å
75G98.7Very high98.3Very high0 Ų038.7 Ų38.70%022%0.219CC..EExtended strand (participates in β ladder)trans-77.5122-176.200000111.6D73 M99 A100D73-G75 VanDerWaalsContact C-N 3.26Å; D73-G75 PolarHBondContact O-N 3.49Å; G75-M99 VanDerWaalsContact O-CA 3.32Å; G75-M99 WeakPolarHBondContact O-CA 3.41Å; G75-A100 WeakPolarHBondContact CA-O 3.48Å; G75-A100 PolarHBondContact N-O 2.9Å; G75-A100 PolarHBondContact O-N 3.3Å
76H98.8Very high98.2Very high17 Ų1737.5 Ų37.58%0.07920%0.204CC..EExtended strand (participates in β ladder)trans-71.1139.3178-71.558.4000110.4F50 T93 F94 M99F50-H76 AromaticContact CE1-CE1 3.47Å; F50-H76 VanDerWaalsContact CE1-CE1 3.47Å; F50-H76 WeakPolarHBondContact CE1-CE1 3.38Å; F50-H76 AromaticContact CZ-CE1 3.71Å; H76-T93 PolarHBondContact CD2-O 3.43Å; H76-T93 PolarHBondContact CD2-OG1 2.93Å; H76-T93 PolarHBondContact NE2-O 3.04Å; H76-T93 PolarHBondContact NE2-OG1 3.08Å; H76-F94 AromaticContact NE2-CD2 3.69Å; H76-F94 AromaticContact NE2-CE2 3.78Å; H76-F94 AromaticContact NE2-CG 3.84Å; H76-M99 HydrophobicContact CB-CE 4.33Å
77L98.7Very high98.2Very high0 Ų039.1 Ų39.10%021%0.211CC..SBendtrans-88.3-53.4166.6-59.3176.5000110.5A25 V28 N98 A100 T133 F165A25-L77 HydrophobicContact CB-CD1 3.45Å; A25-L77 VanDerWaalsContact CB-CD1 3.45Å; V28-L77 HydrophobicContact CB-CB 4.42Å; V28-L77 HydrophobicContact CG1-CB 3.76Å; V28-L77 HydrophobicContact CG1-CD1 4.17Å; V28-L77 HydrophobicContact CG2-CB 3.69Å; L77-N98 PolarHBondContact N-O 3.21Å; L77-A100 HydrophobicContact CD2-CB 4.3Å; L77-T133 HydrophobicContact CB-CG2 4.29Å; L77-T133 HydrophobicContact CD2-CG2 4.28Å; L77-F165 HydrophobicContact CD2-CD1 3.81Å; L77-F165 HydrophobicContact CD2-CE1 3.77Å
78A98.8Very high98.2Very high0 Ų046.1 Ų46.10%024%0.238CC..SBendtrans-88.3108.4167.100000107.9F17 V28 E30 N98F17-A78 HydrophobicContact CB-CB 4.3Å; F17-A78 HydrophobicContact CD2-CB 3.6Å; F17-A78 HydrophobicContact CE2-CB 3.98Å; F17-A78 HydrophobicContact CG-CB 3.92Å; V28-A78 HydrophobicContact CB-CB 4.32Å; V28-A78 HydrophobicContact CG2-CB 3.97Å; E30-A78 HydrophobicContact CG-CB 4.07Å; A78-N98 WeakPolarHBondContact CB-OD1 3.4Å; A78-N98 PolarHBondContact N-OD1 3.27Å; A78-N98 PolarHBondContact O-ND2 3.27Å
79A98.7Very high98.2Very high2 Ų240 Ų402%0.01721%0.208CC..  trans-75.8135.2-166.900000111.5G81 N82 H83 E116A79-G81 PolarHBondContact O-N 3.31Å; A79-N82 WeakPolarHBondContact O-CB 3.4Å; A79-N82 PolarHBondContact O-N 3.01Å; A79-H83 PolarHBondContact O-CD2 3.31Å; A79-E116 HydrophobicContact CB-CG 4.3Å; A79-E116 WeakPolarHBondContact CB-OE1 3.44Å
80A98.4Very high98.2Very high6 Ų632.2 Ų32.25%0.0517%0.167CC..G310 helixtrans-51.7-32.4176.400000113.4N82 H83 R84 V90 T93 F94A80-N82 PolarHBondContact O-N 2.93Å; A80-H83 PolarHBondContact O-N 2.88Å; A80-R84 WeakPolarHBondContact O-CG 3.35Å; A80-V90 HydrophobicContact CB-CG2 3.94Å; A80-T93 WeakPolarHBondContact CA-OG1 3.39Å; A80-T93 WeakPolarHBondContact CB-OG1 3.42Å; A80-F94 HydrophobicContact CB-CE2 3.74Å; A80-F94 HydrophobicContact CB-CZ 4.36Å
81G97.9Very high98.3Very high18 Ų1833.7 Ų33.719%0.18617%0.17CC..G310 helixtrans-64.2-16.1177.500000114.9A79A79-G81 PolarHBondContact O-N 3.31Å
82N98.6Very high98.3Very high1 Ų131.5 Ų31.51%0.00514%0.142CC..G310 helixtrans-93.4-17.5-175.9-60.4-4.2000112.7E30 L32 M37 A79 A80 R120E30-N82 WeakPolarHBondContact OE1-CB 3.41Å; E30-N82 PolarHBondContact OE1-ND2 3.08Å; L32-N82 HydrophobicContact CD1-CB 4.44Å; L32-N82 HydrophobicContact CD2-CB 3.88Å; M37-N82 WeakPolarHBondContact CE-O 3.24Å; A79-N82 WeakPolarHBondContact O-CB 3.4Å; A79-N82 PolarHBondContact O-N 3.01Å; A80-N82 PolarHBondContact O-N 2.93Å; N82-R120 VanDerWaalsContact OD1-CD 3.27Å; N82-R120 WeakPolarHBondContact OD1-CD 3.05Å; N82-R120 WeakPolarHBondContact OD1-CG 3.37Å; N82-R120 PolarHBondContact OD1-NH1 3.23Å
83H98.4Very high98.3Very high0 Ų029.5 Ų29.50%013%0.134CC..  trans-12256-167.1-58.4-65.6000112.4D16 E30 A79 A80 A89 V90 T93D16-H83 PolarHBondContact O-CE1 2.93Å; D16-H83 VanDerWaalsContact O-CE1 3.22Å; D16-H83 PolarHBondContact O-ND1 3.33Å; D16-H83 IonicContact OD2-CE1 3.14Å; D16-H83 IonicContact OD2-CG 3.86Å; D16-H83 IonicContact OD2-ND1 2.65Å; D16-H83 PolarHBondContact OD2-ND1 2.91Å; E30-H83 IonicContact OE1-CE1 2.77Å; E30-H83 IonicContact OE1-NE2 3.76Å; E30-H83 PolarHBondContact OE1-NE2 3.37Å; E30-H83 VanDerWaalsContact OE1-NE2 3.09Å; A79-H83 PolarHBondContact O-CD2 3.31Å; A80-H83 PolarHBondContact O-N 2.88Å; H83-A89 HydrophobicContact CB-CB 4.3Å; H83-V90 WeakPolarHBondContact O-CA 3.2Å; H83-V90 WeakPolarHBondContact O-CB 3.32Å; H83-V90 PolarHBondContact O-N 2.87Å; H83-T93 HydrophobicContact CB-CG2 3.97Å; H83-T93 VanDerWaalsContact CD2-CG2 3.46Å; H83-T93 WeakPolarHBondContact CD2-CG2 3.45Å
84R95.3Very high98.3Very high60 Ų6028.6 Ų28.623%0.22613%0.129CC..  trans-109.427.1-170.3-53.1-175.386.4-176.95.3114.5Y39 S40 V43 A80Y39-R84 HydrophobicContact CD1-CB 3.75Å; Y39-R84 HydrophobicContact CD1-CG 4.19Å; Y39-R84 HydrophobicContact CE1-CB 4.29Å; Y39-R84 HydrophobicContact CE1-CG 4.28Å; Y39-R84 HydrophobicContact CG-CB 4.21Å; S40-R84 PolarHBondContact N-O 2.79Å; S40-R84 VanDerWaalsContact N-O 3.07Å; V43-R84 HydrophobicContact CG1-CB 4.34Å; A80-R84 WeakPolarHBondContact O-CG 3.35Å
85K96.6Very high98.3Very high75 Ų7525.1 Ų25.133%0.32612%0.117SC..SBendtrans-80-40.4173.6-89.5-75-174176.90112.3D35 S40D35-K85 WeakPolarHBondContact O-CE 3.27Å; D35-K85 PolarHBondContact O-NZ 2.81Å; D35-K85 IonicContact OD1-NZ 2.73Å; D35-K85 PolarHBondContact OD1-NZ 3.01Å; D35-K85 WeakPolarHBondContact OD2-CE 3.45Å; D35-K85 IonicContact OD2-NZ 3.1Å; D35-K85 PolarHBondContact OD2-NZ 2.86Å; S40-K85 WeakPolarHBondContact CB-O 3.37Å
86T97.7Very high98.3Very high47 Ų4725.1 Ų25.129%0.28812%0.117SC..SBendtrans-132.6156.1177.970.50000110.2E15 V43 R88 A89 V90E15-T86 VanDerWaalsContact CD-OG1 3.23Å; E15-T86 WeakPolarHBondContact OE1-CB 3.37Å; E15-T86 WeakPolarHBondContact OE1-CG2 3.22Å; E15-T86 PolarHBondContact OE1-OG1 3.21Å; E15-T86 PolarHBondContact OE2-OG1 2.99Å; V43-T86 VanDerWaalsContact CG2-C 3.42Å; T86-R88 VanDerWaalsContact C-N 3.28Å; T86-R88 PolarHBondContact O-N 2.95Å; T86-A89 PolarHBondContact O-N 3Å; T86-A89 VanDerWaalsContact OG1-CB 3.25Å; T86-A89 WeakPolarHBondContact OG1-CB 3.27Å; T86-A89 PolarHBondContact OG1-N 3.25Å; T86-V90 PolarHBondContact O-N 2.83Å
87Q98.2Very high98.3Very high39 Ų3924.4 Ų24.418%0.18211%0.114CC..Hα-helixtrans-63.3-39.7177.5-178.462.332.200110.7D44 A89 V90 E91D44-Q87 PolarHBondContact O-NE2 3.06Å; D44-Q87 VanDerWaalsContact O-NE2 3.08Å; D44-Q87 PolarHBondContact O-OE1 3.41Å; Q87-A89 PolarHBondContact O-N 2.79Å; Q87-V90 WeakPolarHBondContact O-CG1 3.23Å; Q87-V90 PolarHBondContact O-N 2.78Å; Q87-E91 HydrophobicContact CG-CG 4.37Å; Q87-E91 WeakPolarHBondContact CG-OE1 3.42Å; Q87-E91 PolarHBondContact NE2-OE1 3.1Å; Q87-E91 WeakPolarHBondContact O-CB 3.28Å; Q87-E91 VanDerWaalsContact O-CG 3.28Å; Q87-E91 WeakPolarHBondContact O-CG 3.44Å; Q87-E91 PolarHBondContact O-N 2.9Å
88R98.3Very high98.3Very high158 Ų15824.4 Ų24.460%0.59611%0.114SC*.Hα-helixtrans-63-41.8178178.1178.2175.6148.9-0.6112.4E15 T86 V90 E91 Q92E15-R88 VanDerWaalsContact OE2-CB 3.22Å; E15-R88 WeakPolarHBondContact OE2-CB 3.39Å; E15-R88 WeakPolarHBondContact OE2-CD 3.17Å; E15-R88 WeakPolarHBondContact OE2-CG 3.43Å; E15-R88 IonicContact OE2-NE 3.98Å; T86-R88 VanDerWaalsContact C-N 3.28Å; T86-R88 PolarHBondContact O-N 2.95Å; R88-V90 PolarHBondContact O-N 3.46Å; R88-E91 PolarHBondContact O-N 3.47Å; R88-Q92 HydrophobicContact CG-CG 4.44Å; R88-Q92 WeakPolarHBondContact O-CG 3.48Å; R88-Q92 PolarHBondContact O-N 2.91Å
89A98.4Very high98.2Very high2 Ų224.4 Ų24.42%0.01711%0.114CC..Hα-helixtrans-60.1-45.5177.900000111.9E15 D16 H83 T86 Q87 T93E15-A89 HydrophobicContact CB-CB 4.45Å; E15-A89 HydrophobicContact CG-CB 4.43Å; E15-A89 PolarHBondContact OE2-N 3.5Å; D16-A89 HydrophobicContact CB-CB 4Å; H83-A89 HydrophobicContact CB-CB 4.3Å; T86-A89 PolarHBondContact O-N 3Å; T86-A89 VanDerWaalsContact OG1-CB 3.25Å; T86-A89 WeakPolarHBondContact OG1-CB 3.27Å; T86-A89 PolarHBondContact OG1-N 3.25Å; Q87-A89 PolarHBondContact O-N 2.79Å; A89-T93 WeakPolarHBondContact O-CG2 3.13Å
90V98.6Very high98.2Very high0 Ų024.3 Ų24.30%011%0.113CC..Hα-helixtrans-69.6-38.6176.866.90000111.9V43 A80 H83 T86 Q87 R88 Q92 T93 F94V43-V90 HydrophobicContact CG1-CB 4.19Å; V43-V90 HydrophobicContact CG1-CG1 3.47Å; V43-V90 VanDerWaalsContact CG1-CG1 3.47Å; A80-V90 HydrophobicContact CB-CG2 3.94Å; H83-V90 WeakPolarHBondContact O-CA 3.2Å; H83-V90 WeakPolarHBondContact O-CB 3.32Å; H83-V90 PolarHBondContact O-N 2.87Å; T86-V90 PolarHBondContact O-N 2.83Å; Q87-V90 WeakPolarHBondContact O-CG1 3.23Å; Q87-V90 PolarHBondContact O-N 2.78Å; R88-V90 PolarHBondContact O-N 3.46Å; V90-Q92 VanDerWaalsContact C-N 3.31Å; V90-Q92 PolarHBondContact O-N 3.33Å; V90-T93 PolarHBondContact O-N 3.05Å; V90-T93 VanDerWaalsContact O-N 3.12Å; V90-T93 PolarHBondContact O-OG1 2.95Å; V90-F94 HydrophobicContact CG2-CE2 4.34Å; V90-F94 WeakPolarHBondContact O-CD2 3.21Å
91E98.7Very high98.3Very high57 Ų5724 Ų2427%0.26611%0.111SC..Hα-helixtrans-63.7-36.4177.9-77.5171.6-178.400112.6Q87 R88 T93 F94Q87-E91 HydrophobicContact CG-CG 4.37Å; Q87-E91 WeakPolarHBondContact CG-OE1 3.42Å; Q87-E91 PolarHBondContact NE2-OE1 3.1Å; Q87-E91 WeakPolarHBondContact O-CB 3.28Å; Q87-E91 VanDerWaalsContact O-CG 3.28Å; Q87-E91 WeakPolarHBondContact O-CG 3.44Å; Q87-E91 PolarHBondContact O-N 2.9Å; R88-E91 PolarHBondContact O-N 3.47Å; E91-T93 PolarHBondContact O-N 2.93Å; E91-F94 PolarHBondContact O-N 3.39Å
92Q98.8Very high98.3Very high22 Ų2223.1 Ų23.110%0.10310%0.102CC..Hα-helixtrans-64.3-25.5176.4-76177.7-30.100112.3Y14 F17 R88 V90 F94 L95Y14-Q92 HydrophobicContact CD1-CB 4.2Å; Y14-Q92 HydrophobicContact CD1-CG 4.13Å; Y14-Q92 HydrophobicContact CG-CB 4.38Å; F17-Q92 HydrophobicContact CE1-CB 3.96Å; F17-Q92 HydrophobicContact CZ-CB 4.39Å; R88-Q92 HydrophobicContact CG-CG 4.44Å; R88-Q92 WeakPolarHBondContact O-CG 3.48Å; R88-Q92 PolarHBondContact O-N 2.91Å; V90-Q92 VanDerWaalsContact C-N 3.31Å; V90-Q92 PolarHBondContact O-N 3.33Å; Q92-F94 PolarHBondContact O-N 3.33Å; Q92-L95 WeakPolarHBondContact O-CB 3.39Å; Q92-L95 WeakPolarHBondContact O-CG 3.39Å; Q92-L95 PolarHBondContact O-N 2.87Å
93T98.8Very high98.3Very high0 Ų024.9 Ų24.90%011%0.111CC..THydrogen-bonded Turntrans-68.2-19.6174.581.30000112.5F17 H76 A80 H83 A89 V90 E91 L95 N98 M99F17-T93 HydrophobicContact CE1-CG2 4.08Å; H76-T93 PolarHBondContact CD2-O 3.43Å; H76-T93 PolarHBondContact CD2-OG1 2.93Å; H76-T93 PolarHBondContact NE2-O 3.04Å; H76-T93 PolarHBondContact NE2-OG1 3.08Å; A80-T93 WeakPolarHBondContact CA-OG1 3.39Å; A80-T93 WeakPolarHBondContact CB-OG1 3.42Å; H83-T93 HydrophobicContact CB-CG2 3.97Å; H83-T93 VanDerWaalsContact CD2-CG2 3.46Å; H83-T93 WeakPolarHBondContact CD2-CG2 3.45Å; A89-T93 WeakPolarHBondContact O-CG2 3.13Å; V90-T93 PolarHBondContact O-N 3.05Å; V90-T93 VanDerWaalsContact O-N 3.12Å; V90-T93 PolarHBondContact O-OG1 2.95Å; E91-T93 PolarHBondContact O-N 2.93Å; T93-L95 VanDerWaalsContact C-N 3.33Å; T93-N98 PolarHBondContact O-ND2 3.17Å; T93-M99 WeakPolarHBondContact O-CE 3.12Å
94F98.8Very high98.3Very high9 Ų925.2 Ų25.24%0.03911%0.114CC..THydrogen-bonded Turntrans-892.9179.3-75.9-107.7000113.5R45 C48 E49 F50 R51 H76 A80 V90 E91 Q92 L96R45-F94 HydrophobicContact CG-CE2 4.19Å; R45-F94 HydrophobicContact CG-CZ 3.92Å; C48-F94 HydrophobicContact CB-CD1 3.97Å; C48-F94 HydrophobicContact CB-CD2 3.42Å; C48-F94 VanDerWaalsContact CB-CD2 3.42Å; C48-F94 HydrophobicContact CB-CE1 3.9Å; C48-F94 HydrophobicContact CB-CE2 3.35Å; C48-F94 HydrophobicContact CB-CG 3.72Å; C48-F94 HydrophobicContact CB-CZ 3.59Å; E49-F94 WeakPolarHBondContact O-CB 3.41Å; F50-F94 WeakPolarHBondContact CA-O 3.37Å; F50-F94 AromaticContact CD1-CD1 3.95Å; F50-F94 HydrophobicContact CD1-CD1 3.95Å; F50-F94 HydrophobicContact CD2-CD1 4.09Å; F50-F94 HydrophobicContact CD2-CE1 4.44Å; F50-F94 AromaticContact CE1-CD1 3.91Å; F50-F94 HydrophobicContact CE1-CD1 3.91Å; F50-F94 HydrophobicContact CE1-CE1 4.38Å; F50-F94 HydrophobicContact CE2-CD1 4.05Å; F50-F94 HydrophobicContact CE2-CE1 4.04Å; F50-F94 HydrophobicContact CG-CD1 4.05Å; F50-F94 AromaticContact CZ-CD1 3.97Å; F50-F94 HydrophobicContact CZ-CD1 3.97Å; F50-F94 HydrophobicContact CZ-CE1 4.02Å; R51-F94 PolarHBondContact N-O 2.77Å; H76-F94 AromaticContact NE2-CD2 3.69Å; H76-F94 AromaticContact NE2-CE2 3.78Å; H76-F94 AromaticContact NE2-CG 3.84Å; A80-F94 HydrophobicContact CB-CE2 3.74Å; A80-F94 HydrophobicContact CB-CZ 4.36Å; V90-F94 HydrophobicContact CG2-CE2 4.34Å; V90-F94 WeakPolarHBondContact O-CD2 3.21Å; E91-F94 PolarHBondContact O-N 3.39Å; Q92-F94 PolarHBondContact O-N 3.33Å; F94-L96 PolarHBondContact O-N 3.07Å
95L98.7Very high98.5Very high14 Ų1430.5 Ų30.57%0.07314%0.139CC..BIsolated β-bridgetrans-62.4133.3168-69.5174.9000110.2Y14 R51 D53 Q92 T93 S97 N98Y14-L95 HydrophobicContact CD1-CD1 3.99Å; Y14-L95 HydrophobicContact CE1-CD1 3.22Å; R51-L95 HydrophobicContact CG-CD2 3.92Å; R51-L95 CarbonylContact O-C 3.6Å; R51-L95 WeakPolarHBondContact O-CA 3.42Å; D53-L95 HydrophobicContact CB-CB 4.33Å; D53-L95 HydrophobicContact CB-CD1 4.49Å; D53-L95 HydrophobicContact CB-CD2 4.18Å; Q92-L95 WeakPolarHBondContact O-CB 3.39Å; Q92-L95 WeakPolarHBondContact O-CG 3.39Å; Q92-L95 PolarHBondContact O-N 2.87Å; T93-L95 VanDerWaalsContact C-N 3.33Å; L95-S97 PolarHBondContact O-N 3.27Å; L95-S97 VanDerWaalsContact O-N 3.08Å; L95-N98 WeakPolarHBondContact O-CB 3.45Å; L95-N98 PolarHBondContact O-N 2.93Å
96L98.6Very high98.6Very high0 Ų027.4 Ų27.40%013%0.128CC..G310 helixtrans-63.5-16-179.5-66.7178.8000113.4F50 R51 E52 S62 R63 N64 Y67 R74 F94 N98 M99F50-L96 HydrophobicContact CB-CD2 4.38Å; F50-L96 HydrophobicContact CD1-CD2 4.43Å; R51-L96 WeakPolarHBondContact O-CG 3.12Å; R51-L96 PolarHBondContact O-N 3.48Å; E52-L96 HydrophobicContact CG-CD1 4.24Å; S62-L96 WeakPolarHBondContact O-CD1 3.36Å; S62-L96 WeakPolarHBondContact OG-CB 3.43Å; S62-L96 PolarHBondContact OG-O 2.91Å; R63-L96 VanDerWaalsContact CA-CD1 3.46Å; N64-L96 VanDerWaalsContact N-CD1 3.34Å; Y67-L96 HydrophobicContact CE2-CD2 4.34Å; R74-L96 HydrophobicContact CG-CD2 4.21Å; F94-L96 PolarHBondContact O-N 3.07Å; L96-N98 PolarHBondContact O-N 3.42Å; L96-M99 HydrophobicContact CD2-CB 4.38Å; L96-M99 HydrophobicContact CD2-CG 3.83Å; L96-M99 WeakPolarHBondContact O-CB 3.49Å; L96-M99 PolarHBondContact O-N 3.08Å; L96-M99 VanDerWaalsContact O-N 3.1Å
97S98.3Very high98.6Very high2 Ų225.2 Ų25.21%0.01412%0.115CC..G310 helixtrans-63.8-21.6169.261.10000113.9Y14 L95Y14-S97 PolarHBondContact OH-OG 3.37Å; Y14-S97 VanDerWaalsContact OH-OG 3.11Å; L95-S97 PolarHBondContact O-N 3.27Å; L95-S97 VanDerWaalsContact O-N 3.08Å
98N98.7Very high98.6Very high0 Ų024.7 Ų24.70%011%0.113CC..G310 helixtrans-97.67.3176-177.346.9000112.2F17 L77 A78 T93 L95 L96F17-N98 HydrophobicContact CE2-CB 4.3Å; L77-N98 PolarHBondContact N-O 3.21Å; A78-N98 WeakPolarHBondContact CB-OD1 3.4Å; A78-N98 PolarHBondContact N-OD1 3.27Å; A78-N98 PolarHBondContact O-ND2 3.27Å; T93-N98 PolarHBondContact O-ND2 3.17Å; L95-N98 WeakPolarHBondContact O-CB 3.45Å; L95-N98 PolarHBondContact O-N 2.93Å; L96-N98 PolarHBondContact O-N 3.42Å
99M98.7Very high98.6Very high0 Ų024.7 Ų24.70%011%0.113CC..EExtended strand (participates in β ladder)trans-105.6143.5-177.1-58.6-60.413200111.8T24 F50 Y67 R74 G75 H76 T93 L96T24-M99 PolarHBondContact OG1-O 3.06Å; F50-M99 HydrophobicContact CD1-CE 4.39Å; F50-M99 HydrophobicContact CD1-CG 4.46Å; F50-M99 HydrophobicContact CD1-SD 4.12Å; F50-M99 HydrophobicContact CE1-CE 4.11Å; F50-M99 HydrophobicContact CE1-SD 3.67Å; Y67-M99 PolarHBondContact OH-O 3.39Å; R74-M99 HydrophobicContact CB-CB 4.49Å; R74-M99 HydrophobicContact CB-CG 4.14Å; R74-M99 HydrophobicContact CB-SD 3.99Å; R74-M99 VanDerWaalsContact O-SD 3.41Å; G75-M99 VanDerWaalsContact O-CA 3.32Å; G75-M99 WeakPolarHBondContact O-CA 3.41Å; H76-M99 HydrophobicContact CB-CE 4.33Å; T93-M99 WeakPolarHBondContact O-CE 3.12Å; L96-M99 HydrophobicContact CD2-CB 4.38Å; L96-M99 HydrophobicContact CD2-CG 3.83Å; L96-M99 WeakPolarHBondContact O-CB 3.49Å; L96-M99 PolarHBondContact O-N 3.08Å; L96-M99 VanDerWaalsContact O-N 3.1Å
100A98.7Very high98.6Very high0 Ų026.1 Ų26.10%012%0.121CC..EExtended strand (participates in β ladder)trans-129.8147.916400000109.4T24 G75 L77 Q102 P162 F165T24-A100 WeakPolarHBondContact OG1-CB 3.42Å; G75-A100 WeakPolarHBondContact CA-O 3.48Å; G75-A100 PolarHBondContact N-O 2.9Å; G75-A100 PolarHBondContact O-N 3.3Å; L77-A100 HydrophobicContact CD2-CB 4.3Å; A100-Q102 PolarHBondContact O-N 3.49Å; A100-Q102 VanDerWaalsContact O-N 3.13Å; A100-P162 HydrophobicContact CB-CG 4.17Å; A100-F165 HydrophobicContact CB-CE1 3.47Å; A100-F165 VanDerWaalsContact CB-CE1 3.47Å; A100-F165 HydrophobicContact CB-CZ 3.64Å
101P98.8Very high98.6Very high0 Ų026.2 Ų26.20%012%0.121CC..EExtended strand (participates in β ladder)trans-60.5115.8172.9-21.933.1000110.7Y67 Y72 I154 V159 A160 V161 N187Y67-P101 HydrophobicContact CE1-CB 4.25Å; Y67-P101 HydrophobicContact CE1-CG 3.83Å; Y72-P101 HydrophobicContact CD1-CB 4.2Å; Y72-P101 HydrophobicContact CD2-CB 4.35Å; Y72-P101 HydrophobicContact CG-CB 3.85Å; P101-I154 HydrophobicContact CB-CD1 3.95Å; P101-I154 HydrophobicContact CG-CD1 3.66Å; P101-I154 HydrophobicContact CG-CG1 4.15Å; P101-V159 HydrophobicContact CG-CG1 3.87Å; P101-A160 VanDerWaalsContact CD-O 3.3Å; P101-A160 WeakPolarHBondContact CD-O 3.41Å; P101-V161 HydrophobicContact CB-CB 4.26Å; P101-V161 HydrophobicContact CB-CG1 4.22Å; P101-V161 HydrophobicContact CB-CG2 3.82Å; P101-V161 HydrophobicContact CG-CG2 4.09Å; P101-N187 PolarHBondContact O-ND2 3.22Å
102Q98.9Very high98.7Very high0 Ų023.5 Ų23.50%011%0.109CC..EExtended strand (participates in β ladder)trans-121.7141.3179.4-71.9-173.6-11.600110.7D73 A100 G104 F107 N108 F165 N187D73-Q102 PolarHBondContact N-O 3.48Å; D73-Q102 PolarHBondContact O-N 3.36Å; D73-Q102 VanDerWaalsContact O-N 3.11Å; A100-Q102 PolarHBondContact O-N 3.49Å; A100-Q102 VanDerWaalsContact O-N 3.13Å; Q102-G104 PolarHBondContact O-N 3.12Å; Q102-F107 HydrophobicContact CB-CD1 4.1Å; Q102-F107 HydrophobicContact CB-CE1 4.19Å; Q102-F107 HydrophobicContact CG-CD1 4.41Å; Q102-F107 HydrophobicContact CG-CE1 3.99Å; Q102-N108 HydrophobicContact CB-CB 3.89Å; Q102-N108 PolarHBondContact OE1-OD1 2.95Å; Q102-N108 VanDerWaalsContact OE1-OD1 3.05Å; Q102-F165 HydrophobicContact CG-CD2 4.39Å; Q102-F165 HydrophobicContact CG-CE1 4.24Å; Q102-F165 HydrophobicContact CG-CE2 3.56Å; Q102-F165 HydrophobicContact CG-CZ 3.46Å; Q102-F165 VanDerWaalsContact CG-CZ 3.46Å; Q102-N187 WeakPolarHBondContact CA-OD1 3.45Å
103I98.8Very high98.6Very high37 Ų3724.4 Ų24.419%0.1911%0.114CC..EExtended strand (participates in β ladder)trans-58.4128.6168.6-69.4-67000108.9Y72 K105 F107 N108 N187 P189Y72-I103 HydrophobicContact CD1-CD1 4.01Å; Y72-I103 HydrophobicContact CD1-CG1 4.45Å; Y72-I103 HydrophobicContact CE1-CD1 3.63Å; Y72-I103 HydrophobicContact CE1-CG1 4.19Å; I103-K105 WeakPolarHBondContact CG2-O 3.48Å; I103-F107 HydrophobicContact CB-CB 4.02Å; I103-F107 HydrophobicContact CG2-CB 4.11Å; I103-F107 WeakPolarHBondContact O-CB 3.4Å; I103-N108 VanDerWaalsContact O-CB 3.27Å; I103-N108 WeakPolarHBondContact O-CB 3.33Å; I103-N108 PolarHBondContact O-N 3.46Å; I103-N187 WeakPolarHBondContact CG1-O 3.37Å; I103-N187 PolarHBondContact N-OD1 2.82Å; I103-P189 HydrophobicContact CG2-CG 4.07Å
104G98.6Very high98.6Very high8 Ų828 Ų288%0.08213%0.131CC..Iπ-helixtrans-71.3-81.1-175.900000112.5D73 Q102 F107 N108 R109D73-G104 VanDerWaalsContact OD2-CA 3.25Å; D73-G104 WeakPolarHBondContact OD2-CA 3.49Å; Q102-G104 PolarHBondContact O-N 3.12Å; G104-F107 PolarHBondContact O-N 3.21Å; G104-N108 PolarHBondContact O-N 3.4Å; G104-R109 PolarHBondContact O-N 3.19Å
105K98.5Very high98.6Very high171 Ų17127.5 Ų27.574%0.74313%0.129SC*.Iπ-helixtrans-69.7132-180-174.5178.8178.4-177.80110.5I103 F107I103-K105 WeakPolarHBondContact CG2-O 3.48Å; K105-F107 VanDerWaalsContact C-N 3.28Å; K105-F107 PolarHBondContact O-N 3.32Å
106G98.4Very high98.7Very high10 Ų1027.7 Ų27.710%0.10313%0.129CC..Iπ-helixtrans84.7-9.1-177.800000114.5D110 V190G106-D110 WeakPolarHBondContact CA-OD2 3.17Å; G106-D110 PolarHBondContact N-OD2 3.36Å; G106-V190 PolarHBondContact O-N 3.49Å
107F98.8Very high98.7Very high0 Ų033.4 Ų33.40%015%0.154CC..Iπ-helixtrans-133.7-90.8179.8-173.9-108.6000112.4Q102 I103 G104 K105 R109 D110 K111 W112 F165 L185 P186 R188 V190Q102-F107 HydrophobicContact CB-CD1 4.1Å; Q102-F107 HydrophobicContact CB-CE1 4.19Å; Q102-F107 HydrophobicContact CG-CD1 4.41Å; Q102-F107 HydrophobicContact CG-CE1 3.99Å; I103-F107 HydrophobicContact CB-CB 4.02Å; I103-F107 HydrophobicContact CG2-CB 4.11Å; I103-F107 WeakPolarHBondContact O-CB 3.4Å; G104-F107 PolarHBondContact O-N 3.21Å; K105-F107 VanDerWaalsContact C-N 3.28Å; K105-F107 PolarHBondContact O-N 3.32Å; F107-R109 VanDerWaalsContact C-N 3.31Å; F107-R109 PolarHBondContact O-N 3.08Å; F107-D110 CarbonylContact O-C 3.34Å; F107-D110 PolarHBondContact O-N 3.22Å; F107-K111 PolarHBondContact O-N 2.87Å; F107-K111 VanDerWaalsContact O-N 3.12Å; F107-W112 HydrophobicContact CD2-CB 4.47Å; F107-W112 HydrophobicContact CE1-CB 4.44Å; F107-W112 HydrophobicContact CE2-CB 4.31Å; F107-W112 HydrophobicContact CE2-CE3 4.14Å; F107-W112 HydrophobicContact CZ-CB 4.29Å; F107-W112 HydrophobicContact CZ-CD2 4.16Å; F107-W112 AromaticContact CZ-CE3 3.79Å; F107-W112 HydrophobicContact CZ-CE3 3.79Å; F107-W112 HydrophobicContact CZ-CG 4.38Å; F107-W112 WeakPolarHBondContact O-CB 3.44Å; F107-W112 PolarHBondContact O-N 3Å; F107-F165 AromaticContact CE1-CD2 3.6Å; F107-F165 HydrophobicContact CE1-CD2 3.6Å; F107-F165 AromaticContact CE1-CE2 3.88Å; F107-F165 HydrophobicContact CE1-CE2 3.88Å; F107-F165 HydrophobicContact CZ-CB 4.38Å; F107-F165 AromaticContact CZ-CD2 3.59Å; F107-F165 HydrophobicContact CZ-CD2 3.59Å; F107-F165 HydrophobicContact CZ-CE2 4.33Å; F107-F165 HydrophobicContact CZ-CG 4.32Å; F107-L185 HydrophobicContact CE2-CB 3.79Å; F107-L185 HydrophobicContact CE2-CD2 4.28Å; F107-L185 HydrophobicContact CZ-CB 4.45Å; F107-P186 WeakPolarHBondContact CD2-O 3.46Å; F107-P186 VanDerWaalsContact CE2-O 3.31Å; F107-P186 WeakPolarHBondContact CE2-O 3.25Å; F107-R188 WeakPolarHBondContact CB-O 2.84Å; F107-V190 HydrophobicContact CD2-CG2 4.24Å
108N98.7Very high98.7Very high29 Ų2935.5 Ų35.516%0.15516%0.164CC..Iπ-helixtrans-51.1-49.3-177.1177.736000112D73 Q102 I103 G104 D110D73-N108 HydrophobicContact CB-CB 4.45Å; D73-N108 VanDerWaalsContact CB-ND2 3.29Å; D73-N108 WeakPolarHBondContact CB-ND2 3.43Å; D73-N108 PolarHBondContact OD2-ND2 3.4Å; Q102-N108 HydrophobicContact CB-CB 3.89Å; Q102-N108 PolarHBondContact OE1-OD1 2.95Å; Q102-N108 VanDerWaalsContact OE1-OD1 3.05Å; I103-N108 VanDerWaalsContact O-CB 3.27Å; I103-N108 WeakPolarHBondContact O-CB 3.33Å; I103-N108 PolarHBondContact O-N 3.46Å; G104-N108 PolarHBondContact O-N 3.4Å; N108-D110 VanDerWaalsContact C-N 3.27Å; N108-D110 PolarHBondContact O-N 2.99Å
109R98.3Very high98.7Very high157 Ų15735.5 Ų35.559%0.59216%0.164SC*.Iπ-helixtrans-79.9-10.3-175.6-54.8-179-169.8-177.42.5113.3D73 G104 F107D73-R109 IonicContact OD1-CZ 2.91Å; D73-R109 IonicContact OD1-NE 2.73Å; D73-R109 PolarHBondContact OD1-NE 2.9Å; D73-R109 IonicContact OD1-NH2 3.08Å; D73-R109 PolarHBondContact OD1-NH2 3.4Å; D73-R109 WeakPolarHBondContact OD2-CG 3.27Å; D73-R109 IonicContact OD2-CZ 3.98Å; D73-R109 IonicContact OD2-NE 3.65Å; D73-R109 PolarHBondContact OD2-NE 3.31Å; D73-R109 IonicContact OD2-NH2 3.7Å; G104-R109 PolarHBondContact O-N 3.19Å; F107-R109 VanDerWaalsContact C-N 3.31Å; F107-R109 PolarHBondContact O-N 3.08Å
110D98.5Very high98.7Very high32 Ų3236.4 Ų36.417%0.17117%0.167CC..Iπ-helixtrans-128.6-97.4-170.6-66.1-58000111.8G106 F107 N108 W112 N113 E114 R192G106-D110 WeakPolarHBondContact CA-OD2 3.17Å; G106-D110 PolarHBondContact N-OD2 3.36Å; F107-D110 CarbonylContact O-C 3.34Å; F107-D110 PolarHBondContact O-N 3.22Å; N108-D110 VanDerWaalsContact C-N 3.27Å; N108-D110 PolarHBondContact O-N 2.99Å; D110-W112 PolarHBondContact O-N 3.01Å; D110-N113 WeakPolarHBondContact O-CB 3.35Å; D110-N113 PolarHBondContact O-N 2.94Å; D110-E114 PolarHBondContact O-N 2.68Å; D110-R192 IonicContact OD1-CZ 3.34Å; D110-R192 IonicContact OD1-NE 3.4Å; D110-R192 PolarHBondContact OD1-NE 2.82Å; D110-R192 IonicContact OD1-NH2 2.69Å; D110-R192 PolarHBondContact OD1-NH2 2.89Å; D110-R192 IonicContact OD2-NH2 3.58Å
111K98.6Very high98.7Very high3 Ų343.4 Ų43.41%0.01320%0.197CC..Iπ-helixtrans-64.6-35.2-170.4-172.261.257.3-177.30113.5F107 E114 L115 L185 V190 D191 R192 A194 L196 F199F107-K111 PolarHBondContact O-N 2.87Å; F107-K111 VanDerWaalsContact O-N 3.12Å; K111-E114 WeakPolarHBondContact CE-OE2 3.47Å; K111-E114 IonicContact NZ-OE1 3.49Å; K111-E114 PolarHBondContact NZ-OE1 2.99Å; K111-E114 IonicContact NZ-OE2 2.76Å; K111-E114 PolarHBondContact NZ-OE2 3.4Å; K111-E114 WeakPolarHBondContact O-CB 3.28Å; K111-E114 PolarHBondContact O-N 2.87Å; K111-L115 PolarHBondContact O-N 3.33Å; K111-L115 VanDerWaalsContact O-N 3.13Å; K111-L185 HydrophobicContact CG-CD2 3.88Å; K111-V190 HydrophobicContact CB-CB 4.02Å; K111-V190 HydrophobicContact CB-CG1 4.3Å; K111-V190 HydrophobicContact CD-CG1 4.49Å; K111-V190 HydrophobicContact CG-CB 4.08Å; K111-V190 HydrophobicContact CG-CG1 3.84Å; K111-D191 VanDerWaalsContact CE-O 3.27Å; K111-D191 WeakPolarHBondContact CE-O 3.3Å; K111-R192 PolarHBondContact NZ-O 2.87Å; K111-A194 WeakPolarHBondContact CE-O 3.32Å; K111-A194 PolarHBondContact NZ-O 2.88Å; K111-L196 HydrophobicContact CD-CD2 3.91Å; K111-F199 HydrophobicContact CD-CE2 4.29Å; K111-F199 HydrophobicContact CG-CE2 4.4Å
112W98.8Very high98.6Very high0 Ų044.3 Ų44.30%020%0.202CC..Iπ-helixtrans-66.2-45174.9-172.7-107.7000111.1F107 D110 E114 L115 E116 T133 F165 K167 L185F107-W112 HydrophobicContact CD2-CB 4.47Å; F107-W112 HydrophobicContact CE1-CB 4.44Å; F107-W112 HydrophobicContact CE2-CB 4.31Å; F107-W112 HydrophobicContact CE2-CE3 4.14Å; F107-W112 HydrophobicContact CZ-CB 4.29Å; F107-W112 HydrophobicContact CZ-CD2 4.16Å; F107-W112 AromaticContact CZ-CE3 3.79Å; F107-W112 HydrophobicContact CZ-CE3 3.79Å; F107-W112 HydrophobicContact CZ-CG 4.38Å; F107-W112 WeakPolarHBondContact O-CB 3.44Å; F107-W112 PolarHBondContact O-N 3Å; D110-W112 PolarHBondContact O-N 3.01Å; W112-E114 VanDerWaalsContact C-N 3.29Å; W112-E114 PolarHBondContact O-N 2.72Å; W112-L115 HydrophobicContact CE3-CD2 4.2Å; W112-L115 HydrophobicContact CZ3-CD2 3.95Å; W112-L115 WeakPolarHBondContact O-CB 3.47Å; W112-L115 PolarHBondContact O-N 3.26Å; W112-L115 VanDerWaalsContact O-N 3.12Å; W112-E116 PolarHBondContact NE1-OE1 2.97Å; W112-E116 WeakPolarHBondContact O-CG 3.36Å; W112-E116 PolarHBondContact O-N 3.46Å; W112-T133 HydrophobicContact CH2-CG2 3.98Å; W112-T133 HydrophobicContact CZ2-CG2 3.59Å; W112-F165 HydrophobicContact CE3-CB 4.3Å; W112-F165 HydrophobicContact CH2-CB 3.53Å; W112-F165 HydrophobicContact CH2-CG 4.45Å; W112-F165 HydrophobicContact CZ2-CB 4.23Å; W112-F165 HydrophobicContact CZ3-CB 3.57Å; W112-K167 HydrophobicContact CH2-CB 4.24Å; W112-L185 HydrophobicContact CE3-CD2 4.31Å; W112-L185 HydrophobicContact CZ3-CD1 4.28Å
113N98.7Very high98.6Very high41 Ų4144.3 Ų44.322%0.21920%0.202CC..Hα-helixtrans-63.9-31.4173.5179.432.3000112.7D110 E116 K117D110-N113 WeakPolarHBondContact O-CB 3.35Å; D110-N113 PolarHBondContact O-N 2.94Å; N113-E116 PolarHBondContact O-N 2.77Å; N113-K117 WeakPolarHBondContact ND2-CE 3.27Å; N113-K117 WeakPolarHBondContact O-CB 3.27Å; N113-K117 VanDerWaalsContact O-CG 3.25Å; N113-K117 WeakPolarHBondContact O-CG 3.41Å; N113-K117 PolarHBondContact O-N 2.74Å
114E98.7Very high98.6Very high74 Ų7448.7 Ų48.735%0.34622%0.216SC..Hα-helixtrans-60.8-46.2170.7-171.3-173.1142.100111.4D110 K111 W112 E116 K117 H118 L196D110-E114 PolarHBondContact O-N 2.68Å; K111-E114 WeakPolarHBondContact CE-OE2 3.47Å; K111-E114 IonicContact NZ-OE1 3.49Å; K111-E114 PolarHBondContact NZ-OE1 2.99Å; K111-E114 IonicContact NZ-OE2 2.76Å; K111-E114 PolarHBondContact NZ-OE2 3.4Å; K111-E114 WeakPolarHBondContact O-CB 3.28Å; K111-E114 PolarHBondContact O-N 2.87Å; W112-E114 VanDerWaalsContact C-N 3.29Å; W112-E114 PolarHBondContact O-N 2.72Å; E114-E116 PolarHBondContact O-N 2.94Å; E114-K117 PolarHBondContact O-N 3.26Å; E114-H118 PolarHBondContact O-N 2.83Å; E114-L196 HydrophobicContact CG-CD1 4.22Å; E114-L196 HydrophobicContact CG-CD2 4.4Å; E114-L196 HydrophobicContact CG-CG 4.34Å
115L98.9Very high98.6Very high0 Ų051.9 Ų51.90%024%0.242CC..Hα-helixtrans-61.2-42.7174.1176.959.2000111.8K111 W112 K117 H118 V119 K167 Y183 L185 L196K111-L115 PolarHBondContact O-N 3.33Å; K111-L115 VanDerWaalsContact O-N 3.13Å; W112-L115 HydrophobicContact CE3-CD2 4.2Å; W112-L115 HydrophobicContact CZ3-CD2 3.95Å; W112-L115 WeakPolarHBondContact O-CB 3.47Å; W112-L115 PolarHBondContact O-N 3.26Å; W112-L115 VanDerWaalsContact O-N 3.12Å; L115-K117 PolarHBondContact O-N 2.78Å; L115-H118 WeakPolarHBondContact O-CB 3.4Å; L115-H118 PolarHBondContact O-N 2.95Å; L115-V119 PolarHBondContact O-N 3.03Å; L115-K167 HydrophobicContact CD2-CB 3.95Å; L115-K167 HydrophobicContact CD2-CD 4.21Å; L115-K167 HydrophobicContact CG-CD 4.12Å; L115-Y183 HydrophobicContact CD1-CD1 4.09Å; L115-Y183 HydrophobicContact CD1-CD2 3.58Å; L115-Y183 HydrophobicContact CD1-CE1 4.11Å; L115-Y183 HydrophobicContact CD1-CE2 3.58Å; L115-Y183 HydrophobicContact CD1-CG 3.81Å; L115-Y183 HydrophobicContact CD2-CD2 4.4Å; L115-Y183 HydrophobicContact CD2-CG 4.19Å; L115-L185 HydrophobicContact CD2-CD1 3.72Å; L115-L196 HydrophobicContact CB-CD1 4.46Å; L115-L196 HydrophobicContact CB-CD2 3.9Å; L115-L196 HydrophobicContact CD1-CD1 4.34Å; L115-L196 HydrophobicContact CD1-CD2 4.49Å
116E98.8Very high98.5Very high17 Ų1744.8 Ų44.88%0.07921%0.212CC..Hα-helixtrans-62.6-40.5175.5-66.9178.416400112.6A79 W112 N113 E114 H118 V119 R120A79-E116 HydrophobicContact CB-CG 4.3Å; A79-E116 WeakPolarHBondContact CB-OE1 3.44Å; W112-E116 PolarHBondContact NE1-OE1 2.97Å; W112-E116 WeakPolarHBondContact O-CG 3.36Å; W112-E116 PolarHBondContact O-N 3.46Å; N113-E116 PolarHBondContact O-N 2.77Å; E114-E116 PolarHBondContact O-N 2.94Å; E116-H118 VanDerWaalsContact C-N 3.32Å; E116-V119 PolarHBondContact O-N 2.92Å; E116-R120 PolarHBondContact O-N 2.82Å
117K98.6Very high98.5Very high121 Ų12148.7 Ų48.753%0.52623%0.226SC..Hα-helixtrans-63.5-39.2174.6-73.9170-175.9172.10111.3N113 E114 L115 R120 K121N113-K117 WeakPolarHBondContact ND2-CE 3.27Å; N113-K117 WeakPolarHBondContact O-CB 3.27Å; N113-K117 VanDerWaalsContact O-CG 3.25Å; N113-K117 WeakPolarHBondContact O-CG 3.41Å; N113-K117 PolarHBondContact O-N 2.74Å; E114-K117 PolarHBondContact O-N 3.26Å; L115-K117 PolarHBondContact O-N 2.78Å; K117-R120 VanDerWaalsContact CG-NH2 3.27Å; K117-R120 PolarHBondContact O-N 3.12Å; K117-K121 PolarHBondContact O-N 3.35Å
118H98.7Very high98.5Very high46 Ų4649.7 Ų49.721%0.21323%0.232CC..Hα-helixtrans-61.8-48.4174.4173.865.4000111.6E114 L115 E116 R120 K121 L122 E181 Y183 L196E114-H118 PolarHBondContact O-N 2.83Å; L115-H118 WeakPolarHBondContact O-CB 3.4Å; L115-H118 PolarHBondContact O-N 2.95Å; E116-H118 VanDerWaalsContact C-N 3.32Å; H118-R120 VanDerWaalsContact C-N 3.31Å; H118-R120 PolarHBondContact O-N 3.38Å; H118-K121 WeakPolarHBondContact O-CA 3.12Å; H118-K121 VanDerWaalsContact O-CB 3.27Å; H118-K121 WeakPolarHBondContact O-CB 3.5Å; H118-K121 PolarHBondContact O-N 2.56Å; H118-L122 PolarHBondContact O-N 3.48Å; H118-E181 IonicContact CD2-OE2 3.75Å; H118-E181 IonicContact CE1-OE2 2.83Å; H118-E181 IonicContact NE2-OE1 3.72Å; H118-E181 IonicContact NE2-OE2 3.82Å; H118-E181 PolarHBondContact NE2-OE2 3.24Å; H118-Y183 PolarHBondContact CD2-OH 2.73Å; H118-Y183 PolarHBondContact NE2-OH 2.89Å; H118-L196 HydrophobicContact CB-CD1 3.63Å
119V98.8Very high98.5Very high0 Ų048.3 Ų48.30%022%0.224CC..Hα-helixtrans-60.2-39.6176.2171.10000112L32 L115 E116 K121 L122 A123 V129 V131 K167 A169L32-V119 HydrophobicContact CD1-CG1 4.04Å; L115-V119 PolarHBondContact O-N 3.03Å; E116-V119 PolarHBondContact O-N 2.92Å; V119-K121 VanDerWaalsContact C-N 3.33Å; V119-K121 PolarHBondContact O-N 2.85Å; V119-L122 WeakPolarHBondContact O-CB 3.37Å; V119-L122 PolarHBondContact O-N 2.87Å; V119-A123 PolarHBondContact O-N 3.3Å; V119-V129 HydrophobicContact CG1-CG1 4.42Å; V119-V131 HydrophobicContact CG1-CG1 4.38Å; V119-V131 HydrophobicContact CG1-CG2 3.56Å; V119-K167 HydrophobicContact CG2-CD 3.79Å; V119-A169 HydrophobicContact CG2-CB 4.46Å
120R98.7Very high98.5Very high19 Ų1941.5 Ų41.57%0.07220%0.199CC..Hα-helixtrans-64.6-35.4172.1-73.3-172.8-69.2-86.90.3112.9M37 N82 E116 K117 H118 A123 R124M37-R120 HydrophobicContact SD-CB 4.27Å; M37-R120 HydrophobicContact SD-CG 3.93Å; N82-R120 VanDerWaalsContact OD1-CD 3.27Å; N82-R120 WeakPolarHBondContact OD1-CD 3.05Å; N82-R120 WeakPolarHBondContact OD1-CG 3.37Å; N82-R120 PolarHBondContact OD1-NH1 3.23Å; E116-R120 PolarHBondContact O-N 2.82Å; K117-R120 VanDerWaalsContact CG-NH2 3.27Å; K117-R120 PolarHBondContact O-N 3.12Å; H118-R120 VanDerWaalsContact C-N 3.31Å; H118-R120 PolarHBondContact O-N 3.38Å; R120-A123 PolarHBondContact O-N 3.15Å; R120-R124 WeakPolarHBondContact O-CG 3.4Å; R120-R124 PolarHBondContact O-N 3.21Å
121K98.5Very high98.5Very high147 Ų14740 Ų4064%0.63919%0.19SC*.Hα-helixtrans-62.6-44.3173.7-175.4-175.3176.5-177.20110.5K117 H118 V119 A123 R124 A125K117-K121 PolarHBondContact O-N 3.35Å; H118-K121 WeakPolarHBondContact O-CA 3.12Å; H118-K121 VanDerWaalsContact O-CB 3.27Å; H118-K121 WeakPolarHBondContact O-CB 3.5Å; H118-K121 PolarHBondContact O-N 2.56Å; V119-K121 VanDerWaalsContact C-N 3.33Å; V119-K121 PolarHBondContact O-N 2.85Å; K121-A123 VanDerWaalsContact C-N 3.34Å; K121-A123 PolarHBondContact O-N 2.81Å; K121-R124 PolarHBondContact O-N 3.46Å; K121-A125 PolarHBondContact O-N 3.03Å
122L98.4Very high98.5Very high19 Ų1939.9 Ų39.910%0.09919%0.19CC..Hα-helixtrans-59.1-45.9173.2-63174.1000111.2H118 V119 R124 A125 N126 V129 V171 F179 E181H118-L122 PolarHBondContact O-N 3.48Å; V119-L122 WeakPolarHBondContact O-CB 3.37Å; V119-L122 PolarHBondContact O-N 2.87Å; L122-R124 VanDerWaalsContact C-N 3.29Å; L122-R124 PolarHBondContact O-N 3.15Å; L122-A125 PolarHBondContact O-N 3.06Å; L122-A125 VanDerWaalsContact O-N 3.08Å; L122-N126 WeakPolarHBondContact O-CB 3.47Å; L122-N126 PolarHBondContact O-N 2.9Å; L122-N126 PolarHBondContact O-ND2 3.4Å; L122-V129 HydrophobicContact CB-CG2 4.28Å; L122-V171 HydrophobicContact CD1-CG2 4.15Å; L122-F179 HydrophobicContact CD2-CE2 4.41Å; L122-F179 HydrophobicContact CD2-CZ 4.17Å; L122-E181 WeakPolarHBondContact CD1-OE2 3.49Å
123A98.5Very high98.6Very high0 Ų039.9 Ų39.90%019%0.19CC..Hα-helixtrans-62.7-31.1-179.100000114L32 T33 P34 M37 V119 R120 K121 V129L32-A123 HydrophobicContact CB-CB 3.61Å; L32-A123 HydrophobicContact CD1-CB 4.11Å; T33-A123 CarbonylContact C-O 3.49Å; P34-A123 WeakPolarHBondContact CD-O 3.24Å; P34-A123 WeakPolarHBondContact CG-O 3.39Å; M37-A123 HydrophobicContact CG-CB 3.76Å; M37-A123 HydrophobicContact SD-CB 4.07Å; V119-A123 PolarHBondContact O-N 3.3Å; R120-A123 PolarHBondContact O-N 3.15Å; K121-A123 VanDerWaalsContact C-N 3.34Å; K121-A123 PolarHBondContact O-N 2.81Å; A123-V129 HydrophobicContact CB-CB 4.28Å; A123-V129 HydrophobicContact CB-CG2 4.14Å
124R98.2Very high98.6Very high129 Ų12937.9 Ų37.949%0.48718%0.179SC..Hα-helixtrans-75.5-30.5173.8-68.8-177.3-164121.51.6113.2M37 R120 K121 L122M37-R124 HydrophobicContact CB-CG 3.71Å; M37-R124 HydrophobicContact CG-CG 4Å; R120-R124 WeakPolarHBondContact O-CG 3.4Å; R120-R124 PolarHBondContact O-N 3.21Å; K121-R124 PolarHBondContact O-N 3.46Å; L122-R124 VanDerWaalsContact C-N 3.29Å; L122-R124 PolarHBondContact O-N 3.15Å
125A97.8Very high98.6Very high75 Ų7534.9 Ų34.962%0.6217%0.166SC*.Hα-helixtrans-93.1-11.7-173.700000114K121 L122K121-A125 PolarHBondContact O-N 3.03Å; L122-A125 PolarHBondContact O-N 3.06Å; L122-A125 VanDerWaalsContact O-N 3.08Å
126N98.2Very high98.6Very high21 Ų2135 Ų3511%0.11217%0.167CC..SBendtrans-128.1157.5-171.5-67.2-80.7000111.1P34 L122 V129 V171 E172P34-N126 WeakPolarHBondContact CD-O 3.12Å; P34-N126 WeakPolarHBondContact CG-O 3.46Å; L122-N126 WeakPolarHBondContact O-CB 3.47Å; L122-N126 PolarHBondContact O-N 2.9Å; L122-N126 PolarHBondContact O-ND2 3.4Å; N126-V129 HydrophobicContact CB-CG2 4.31Å; N126-V171 HydrophobicContact CB-CG1 3.43Å; N126-V171 VanDerWaalsContact CB-CG1 3.43Å; N126-E172 WeakPolarHBondContact CB-O 3.42Å
127K97.8Very high98.5Very high92 Ų9237.5 Ų37.540%0.418%0.176SC..SBendtrans-65-47.1-173.5-176.5-177.7170.8-162.20111.8E172 S176K127-E172 WeakPolarHBondContact CB-O 3.41Å; K127-E172 HydrophobicContact CD-CG 4.31Å; K127-E172 WeakPolarHBondContact CD-OE1 3.18Å; K127-E172 WeakPolarHBondContact CE-OE1 3.48Å; K127-E172 PolarHBondContact N-O 2.69Å; K127-E172 IonicContact NZ-OE1 2.79Å; K127-E172 PolarHBondContact NZ-OE1 2.88Å; K127-S176 PolarHBondContact NZ-OG 3.08Å
128N98.4Very high98.5Very high22 Ų2234 Ų3412%0.11816%0.163CC..EExtended strand (participates in β ladder)trans-141.1142.4176.1-65.9-68.8000110.4H31 T33 Y130 E172H31-N128 PolarHBondContact NE2-OD1 3.34Å; T33-N128 WeakPolarHBondContact CG2-OD1 3.38Å; N128-Y130 HydrophobicContact CB-CD2 4.38Å; N128-Y130 HydrophobicContact CB-CE2 3.59Å; N128-E172 HydrophobicContact CB-CB 3.98Å; N128-E172 PolarHBondContact N-O 3.27Å; N128-E172 PolarHBondContact ND2-OE2 3.34Å; N128-E172 PolarHBondContact O-N 3.15Å
129V98.7Very high98.5Very high0 Ų035.3 Ų35.30%018%0.175CC..EExtended strand (participates in β ladder)trans-130.8120169.7-179.70000108.8L32 V119 L122 A123 N126 V131 A169 L170 V171L32-V129 HydrophobicContact CB-CB 4.34Å; L32-V129 PolarHBondContact N-O 3.22Å; L32-V129 PolarHBondContact O-N 2.89Å; V119-V129 HydrophobicContact CG1-CG1 4.42Å; L122-V129 HydrophobicContact CB-CG2 4.28Å; A123-V129 HydrophobicContact CB-CB 4.28Å; A123-V129 HydrophobicContact CB-CG2 4.14Å; N126-V129 HydrophobicContact CB-CG2 4.31Å; V129-V131 HydrophobicContact CG1-CG2 3.76Å; V129-A169 HydrophobicContact CG1-CB 4.36Å; V129-L170 CarbonylContact C-O 3.59Å; V129-L170 WeakPolarHBondContact CA-O 3.42Å; V129-V171 HydrophobicContact CG1-CG2 4.21Å; V129-V171 HydrophobicContact CG2-CB 4.43Å; V129-V171 HydrophobicContact CG2-CG1 3.99Å; V129-V171 HydrophobicContact CG2-CG2 4.11Å
130Y98.7Very high98.3Very high14 Ų1444.3 Ų44.36%0.05521%0.209CC..EExtended strand (participates in β ladder)trans-103.7128.6174.7-58-98.4000108.1R2 F3 E30 H31 N128 A169 L170 W178 F215R2-Y130 HydrophobicContact CB-CE1 4.12Å; R2-Y130 WeakPolarHBondContact CD-OH 3.41Å; F3-Y130 HydrophobicContact CD2-CD1 4.21Å; F3-Y130 HydrophobicContact CD2-CD2 4.04Å; F3-Y130 HydrophobicContact CD2-CE1 4.34Å; F3-Y130 HydrophobicContact CD2-CE2 4.23Å; F3-Y130 HydrophobicContact CD2-CG 4.04Å; F3-Y130 HydrophobicContact CE2-CD1 4.34Å; F3-Y130 AromaticContact CE2-CD2 3.62Å; F3-Y130 HydrophobicContact CE2-CD2 3.62Å; F3-Y130 HydrophobicContact CE2-CE1 4.15Å; F3-Y130 AromaticContact CE2-CE2 3.45Å; F3-Y130 HydrophobicContact CE2-CE2 3.45Å; F3-Y130 VanDerWaalsContact CE2-CE2 3.45Å; F3-Y130 HydrophobicContact CE2-CG 4.07Å; F3-Y130 AromaticContact CE2-CZ 3.71Å; F3-Y130 HydrophobicContact CZ-CE2 4.39Å; E30-Y130 WeakPolarHBondContact O-CA 3.42Å; H31-Y130 HydrophobicContact CB-CD1 4.1Å; H31-Y130 HydrophobicContact CB-CE1 4.17Å; H31-Y130 AromaticContact CD2-CD1 3.97Å; H31-Y130 AromaticContact CD2-CE1 3.62Å; H31-Y130 AromaticContact CD2-CZ 3.72Å; H31-Y130 AromaticContact CG-CE1 3.76Å; H31-Y130 AromaticContact NE2-CZ 3.84Å; N128-Y130 HydrophobicContact CB-CD2 4.38Å; N128-Y130 HydrophobicContact CB-CE2 3.59Å; Y130-A169 CarbonylContact O-C 3.58Å; Y130-A169 WeakPolarHBondContact O-CA 3.18Å; Y130-L170 PolarHBondContact N-O 2.78Å; Y130-L170 PolarHBondContact O-N 3.14Å; Y130-W178 HydrophobicContact CD2-CZ3 4.1Å; Y130-W178 AromaticContact CE2-CH2 3.92Å; Y130-W178 HydrophobicContact CE2-CH2 3.92Å; Y130-W178 AromaticContact CE2-CZ3 3.96Å; Y130-W178 HydrophobicContact CE2-CZ3 3.96Å; Y130-F215 WeakPolarHBondContact O-CZ 3.49Å
131V98.9Very high98.2Very high0 Ų051.3 Ų51.30%024%0.236CC..EExtended strand (participates in β ladder)trans-124.8122.9-172.3-168.80000109.2M29 E30 L32 V119 V129 K167 V168M29-V131 CarbonylContact C-O 3.04Å; M29-V131 WeakPolarHBondContact CA-O 3.31Å; E30-V131 HydrophobicContact CB-CB 4.27Å; E30-V131 PolarHBondContact N-O 2.86Å; E30-V131 PolarHBondContact O-N 2.94Å; L32-V131 HydrophobicContact CD1-CG2 4.04Å; L32-V131 HydrophobicContact CG-CG2 4.43Å; V119-V131 HydrophobicContact CG1-CG1 4.38Å; V119-V131 HydrophobicContact CG1-CG2 3.56Å; V129-V131 HydrophobicContact CG1-CG2 3.76Å; V131-K167 HydrophobicContact CG1-CD 3.93Å; V131-K167 HydrophobicContact CG1-CG 3.61Å; V131-V168 CarbonylContact C-O 3.47Å; V131-V168 WeakPolarHBondContact CA-O 3.46Å
132C98.8Very high98Very high0 Ų048.1 Ų48.10%022%0.223CC..EExtended strand (participates in β ladder)trans-103.9126.7168.4-168.80000108.6V28 M29 F166 K167 V168 I214 F215V28-C132 WeakPolarHBondContact O-CA 3.31Å; M29-C132 HydrophobicContact CE-CB 3.85Å; M29-C132 HydrophobicContact SD-CB 3.78Å; C132-F166 HydrophobicContact CB-CE2 4.3Å; C132-K167 CarbonylContact O-C 3.49Å; C132-K167 WeakPolarHBondContact O-CA 3.36Å; C132-V168 HydrophobicContact CB-CB 4.47Å; C132-V168 PolarHBondContact N-O 3.31Å; C132-V168 PolarHBondContact O-N 3.47Å; C132-I214 HydrophobicContact CB-CG2 3.81Å; C132-F215 HydrophobicContact CB-CZ 4.25Å
133T98.9Very high97.9Very high0 Ų052.7 Ų52.70%026%0.263CS..EExtended strand (participates in β ladder)trans-131.1139.7179.9-51.10000109.7W27 V28 L77 W112 F166 K167W27-T133 CarbonylContact C-O 3.58Å; W27-T133 VanDerWaalsContact CA-O 3.25Å; W27-T133 WeakPolarHBondContact CA-O 3.35Å; V28-T133 PolarHBondContact N-O 3.4Å; V28-T133 PolarHBondContact O-N 2.88Å; L77-T133 HydrophobicContact CB-CG2 4.29Å; L77-T133 HydrophobicContact CD2-CG2 4.28Å; W112-T133 HydrophobicContact CH2-CG2 3.98Å; W112-T133 HydrophobicContact CZ2-CG2 3.59Å; T133-F166 WeakPolarHBondContact CA-O 3.25Å; T133-F166 WeakPolarHBondContact CG2-O 3.3Å; T133-K167 PolarHBondContact OG1-NZ 2.78Å
134G98.7Very high97.8Very high0 Ų057.9 Ų57.90%029%0.291CS..EExtended strand (participates in β ladder)trans-169.4169.6176.500000114.1F165 F166G134-F165 WeakPolarHBondContact O-CA 3.4Å; G134-F166 PolarHBondContact N-O 3.32Å; G134-F166 WeakPolarHBondContact O-CD1 3.44Å; G134-F166 PolarHBondContact O-N 3.1Å
135P98.8Very high97.7Very high10 Ų1053.3 Ų53.37%0.06529%0.285CS..EExtended strand (participates in β ladder)trans-75.5160.3173.133.6-36.8000112.3T24 A25 H26 Y137 P162 F165T24-P135 HydrophobicContact CG2-CG 4.41Å; A25-P135 WeakPolarHBondContact O-CD 3.46Å; A25-P135 WeakPolarHBondContact O-CG 3.19Å; H26-P135 WeakPolarHBondContact O-CD 3.34Å; P135-Y137 HydrophobicContact CB-CE2 4.31Å; P135-Y137 HydrophobicContact CG-CE2 4.39Å; P135-P162 HydrophobicContact CB-CB 3.54Å; P135-P162 HydrophobicContact CB-CG 3.34Å; P135-P162 HydrophobicContact CG-CG 4.49Å; P135-F165 HydrophobicContact CB-CD1 4.36Å; P135-F165 HydrophobicContact CB-CE1 4.14Å
136L98.7Very high97.7Very high4 Ų456.6 Ų56.62%0.02129%0.285CS..EExtended strand (participates in β ladder)trans-134.5148.3167-63.8173.1000110.1L138 T163 H164 F166 V184 A209 A210L136-L138 HydrophobicContact CB-CD2 3.94Å; L136-L138 HydrophobicContact CB-CG 4.08Å; L136-L138 HydrophobicContact CD1-CD2 4.21Å; L136-T163 PolarHBondContact O-N 3.32Å; L136-T163 PolarHBondContact O-OG1 3.41Å; L136-H164 HydrophobicContact CB-CB 4.12Å; L136-H164 PolarHBondContact N-O 2.96Å; L136-H164 PolarHBondContact O-N 3.26Å; L136-H164 VanDerWaalsContact O-N 3.15Å; L136-F166 HydrophobicContact CD1-CB 4.08Å; L136-F166 HydrophobicContact CD1-CD1 4.36Å; L136-F166 HydrophobicContact CD2-CD1 3.87Å; L136-F166 HydrophobicContact CD2-CE1 4.42Å; L136-F166 HydrophobicContact CG-CB 4.46Å; L136-F166 HydrophobicContact CG-CD1 3.88Å; L136-V184 HydrophobicContact CD1-CG1 4.06Å; L136-V184 HydrophobicContact CD1-CG2 4.09Å; L136-A209 HydrophobicContact CD2-CB 3.98Å; L136-A210 HydrophobicContact CD2-CB 3.7Å
137Y98.4Very high97.6Very high68 Ų6860.8 Ų60.827%0.26731%0.307SS..  trans-120.473.9176.8-56.4-83.9000109.4T24 P135 V149 F151 A160 P162T24-Y137 WeakPolarHBondContact CG2-OH 3.44Å; P135-Y137 HydrophobicContact CB-CE2 4.31Å; P135-Y137 HydrophobicContact CG-CE2 4.39Å; Y137-V149 WeakPolarHBondContact O-CG1 3.32Å; Y137-F151 HydrophobicContact CD1-CB 4.21Å; Y137-F151 AromaticContact CD1-CD1 3.52Å; Y137-F151 HydrophobicContact CD1-CD1 3.52Å; Y137-F151 HydrophobicContact CD1-CD2 4.27Å; Y137-F151 AromaticContact CD1-CE1 3.86Å; Y137-F151 HydrophobicContact CD1-CE1 3.86Å; Y137-F151 AromaticContact CD1-CG 3.75Å; Y137-F151 HydrophobicContact CD1-CG 3.75Å; Y137-F151 HydrophobicContact CD1-CZ 4.36Å; Y137-F151 HydrophobicContact CE1-CD1 4.24Å; Y137-F151 HydrophobicContact CE1-CD2 4.18Å; Y137-F151 HydrophobicContact CE1-CE1 4.46Å; Y137-F151 HydrophobicContact CE1-CE2 4.41Å; Y137-F151 HydrophobicContact CE1-CG 4.09Å; Y137-F151 HydrophobicContact CG-CD1 4.24Å; Y137-F151 HydrophobicContact CG-CE1 4.3Å; Y137-A160 HydrophobicContact CE1-CB 3.89Å; Y137-A160 WeakPolarHBondContact OH-CB 3.47Å; Y137-P162 HydrophobicContact CE1-CB 4.26Å; Y137-P162 HydrophobicContact CE1-CG 4.35Å
138L98.1Very high97.6Very high48 Ų4858.6 Ų58.625%0.25130%0.302SS..  trans-76.3141.3-173.3-56-171.8000112.7L136 T163 H164 V184 A209L136-L138 HydrophobicContact CB-CD2 3.94Å; L136-L138 HydrophobicContact CB-CG 4.08Å; L136-L138 HydrophobicContact CD1-CD2 4.21Å; L138-T163 PolarHBondContact N-OG1 2.98Å; L138-H164 HydrophobicContact CD1-CB 4.22Å; L138-H164 HydrophobicContact CG-CB 4.47Å; L138-V184 HydrophobicContact CD1-CG1 4.43Å; L138-A209 HydrophobicContact CD2-CB 3.54Å
139P97.4Very high97.6Very high73 Ų7361.1 Ų61.147%0.47432%0.319SS..  trans-73150.1178.330.6-35.2000112L147 C148 V149P139-L147 HydrophobicContact CB-CB 4.28Å; P139-L147 HydrophobicContact CB-CD2 4.46Å; P139-C148 CarbonylContact C-O 3.48Å; P139-C148 VanDerWaalsContact CA-O 3.23Å; P139-C148 WeakPolarHBondContact CA-O 3.41Å; P139-V149 HydrophobicContact CB-CG2 3.91Å
140R95.6Very high97.5Very high189 Ų18965.8 Ų65.871%0.71335%0.347SS*.EExtended strand (participates in β ladder)trans-120.5147.3169.1-175.8177.6174.5-178.4-2.2109.5E142 L147 C148R140-E142 PolarHBondContact O-N 3.01Å; R140-L147 WeakPolarHBondContact O-CA 3.42Å; R140-C148 PolarHBondContact N-O 2.95Å; R140-C148 PolarHBondContact O-N 3.49Å
141R96.3Very high97.5Very high167 Ų16769.3 Ų69.363%0.6336%0.363SS*.EExtended strand (participates in β ladder)trans-76.8120171.1-166.5176-63.8-92.15.4109.4G145 K146 L147R141-G145 PolarHBondContact NH1-O 3.46Å; R141-K146 WeakPolarHBondContact CA-O 3.32Å; R141-L147 HydrophobicContact CB-CD2 4.08Å
142E95.2Very high97.4Very high79 Ų7974 Ų7437%0.36939%0.385SS..  trans-80.9168.5176.1-67.2-61152.300111.2R140 N144 G145 K146 C148R140-E142 PolarHBondContact O-N 3.01Å; E142-N144 PolarHBondContact O-N 3.26Å; E142-N144 VanDerWaalsContact O-N 3.12Å; E142-G145 PolarHBondContact O-N 3.22Å; E142-K146 PolarHBondContact N-O 3.39Å; E142-C148 HydrophobicContact CG-CB 3.78Å
143A95.4Very high97.4Very high115 Ų11577.2 Ų77.295%0.9540%0.404SS*.THydrogen-bonded Turntrans-58.4-26.6-179.500000113.6G145A143-G145 PolarHBondContact O-N 2.88Å
144N95.8Very high97.4Very high109 Ų10977.5 Ų77.558%0.58341%0.406SS*.THydrogen-bonded Turntrans-80.55.5175.46811000113.9E142 K146E142-N144 PolarHBondContact O-N 3.26Å; E142-N144 VanDerWaalsContact O-N 3.12Å; N144-K146 VanDerWaalsContact C-N 3.27Å; N144-K146 PolarHBondContact O-N 3.25Å; N144-K146 WeakPolarHBondContact OD1-CB 3.36Å; N144-K146 PolarHBondContact OD1-N 2.93Å
145G96.7Very high97.4Very high34 Ų3479.4 Ų79.435%0.35143%0.425SS..SBendtrans80.3-7179.300000115.5R141 E142 A143R141-G145 PolarHBondContact NH1-O 3.46Å; E142-G145 PolarHBondContact O-N 3.22Å; A143-G145 PolarHBondContact O-N 2.88Å
146K97.9Very high97.3Very high143 Ų14388.2 Ų88.262%0.62246%0.462SS*.  trans-79.9151.7177.6-61.1-177.4179.5-179.80111.1R141 E142 N144R141-K146 WeakPolarHBondContact CA-O 3.32Å; E142-K146 PolarHBondContact N-O 3.39Å; N144-K146 VanDerWaalsContact C-N 3.27Å; N144-K146 PolarHBondContact O-N 3.25Å; N144-K146 WeakPolarHBondContact OD1-CB 3.36Å; N144-K146 PolarHBondContact OD1-N 2.93Å
147L97.3Very high97.2Very high110 Ų11090.2 Ų90.258%0.57647%0.473SS*.EExtended strand (participates in β ladder)trans-87.3125.3170-72.4172.3000108.9P139 R140 R141P139-L147 HydrophobicContact CB-CB 4.28Å; P139-L147 HydrophobicContact CB-CD2 4.46Å; R140-L147 WeakPolarHBondContact O-CA 3.42Å; R141-L147 HydrophobicContact CB-CD2 4.08Å
148C97.5Very high97.2Very high45 Ų4593.1 Ų93.130%0.30449%0.489SS..EExtended strand (participates in β ladder)trans-126.5143.4177.3-650000109.8P139 R140 E142P139-C148 CarbonylContact C-O 3.48Å; P139-C148 VanDerWaalsContact CA-O 3.23Å; P139-C148 WeakPolarHBondContact CA-O 3.41Å; R140-C148 PolarHBondContact N-O 2.95Å; R140-C148 PolarHBondContact O-N 3.49Å; E142-C148 HydrophobicContact CG-CB 3.78Å
149V97.7Very high97.2Very high76 Ų7690.9 Ų90.946%0.46148%0.477SS..  trans-97.2115.4166.6177.60000106.9Y137 P139 F151Y137-V149 WeakPolarHBondContact O-CG1 3.32Å; P139-V149 HydrophobicContact CB-CG2 3.91Å; V149-F151 HydrophobicContact CG1-CD1 3.91Å; V149-F151 HydrophobicContact CG1-CE1 4.04Å
150T96.9Very high97.3Very high97 Ų9788.1 Ų88.160%0.59546%0.46SS*.  trans-128.4130.3-179.9-51.10000108.5
151F97.8Very high97.4Very high89 Ų8979.5 Ų79.539%0.3943%0.429SS..  trans-149.6153.3175.754.1-93.9000110.6Y137 V149 V153 A160 V161 T163Y137-F151 HydrophobicContact CD1-CB 4.21Å; Y137-F151 AromaticContact CD1-CD1 3.52Å; Y137-F151 HydrophobicContact CD1-CD1 3.52Å; Y137-F151 HydrophobicContact CD1-CD2 4.27Å; Y137-F151 AromaticContact CD1-CE1 3.86Å; Y137-F151 HydrophobicContact CD1-CE1 3.86Å; Y137-F151 AromaticContact CD1-CG 3.75Å; Y137-F151 HydrophobicContact CD1-CG 3.75Å; Y137-F151 HydrophobicContact CD1-CZ 4.36Å; Y137-F151 HydrophobicContact CE1-CD1 4.24Å; Y137-F151 HydrophobicContact CE1-CD2 4.18Å; Y137-F151 HydrophobicContact CE1-CE1 4.46Å; Y137-F151 HydrophobicContact CE1-CE2 4.41Å; Y137-F151 HydrophobicContact CE1-CG 4.09Å; Y137-F151 HydrophobicContact CG-CD1 4.24Å; Y137-F151 HydrophobicContact CG-CE1 4.3Å; V149-F151 HydrophobicContact CG1-CD1 3.91Å; V149-F151 HydrophobicContact CG1-CE1 4.04Å; F151-V153 HydrophobicContact CD2-CG1 4.29Å; F151-V153 HydrophobicContact CE2-CG1 4.09Å; F151-A160 HydrophobicContact CD2-CB 3.95Å; F151-A160 HydrophobicContact CE2-CB 3.71Å; F151-V161 WeakPolarHBondContact CB-O 3.42Å; F151-T163 HydrophobicContact CB-CG2 4.23Å
152E98.4Very high97.5Very high97 Ų9771.7 Ų71.745%0.45340%0.4SS..  trans-75.7151.3174.4-178.7175.5160.400110.8Y72 I154 V161Y72-E152 PolarHBondContact OH-OE2 3.13Å; E152-I154 HydrophobicContact CG-CG2 4.19Å; E152-I154 WeakPolarHBondContact OE1-CG2 3.31Å; E152-V161 HydrophobicContact CB-CB 4.12Å; E152-V161 HydrophobicContact CB-CG2 3.9Å; E152-V161 HydrophobicContact CG-CG2 4.13Å; E152-V161 WeakPolarHBondContact O-CB 3.36Å; E152-V161 WeakPolarHBondContact O-CG2 3.38Å; E152-V161 PolarHBondContact O-N 3.2Å
153V98.5Very high97.7Very high68 Ų6869.3 Ų69.341%0.41239%0.391SS..EExtended strand (participates in β ladder)trans-120138.2165.4-650000108.9F151 H158 V159F151-V153 HydrophobicContact CD2-CG1 4.29Å; F151-V153 HydrophobicContact CE2-CG1 4.09Å; V153-H158 HydrophobicContact CB-CB 3.97Å; V153-H158 HydrophobicContact CG1-CB 4.41Å; V153-H158 HydrophobicContact CG2-CB 4.07Å; V153-V159 CarbonylContact C-O 3.43Å; V153-V159 WeakPolarHBondContact CA-O 3.28Å
154I98.5Very high97.8Very high7 Ų766.2 Ų66.24%0.03636%0.356CS..EExtended strand (participates in β ladder)trans-114.7150.3-176.664.8173.1000112.1D66 Y67 Y72 P101 E152 H158 V159 V161D66-I154 WeakPolarHBondContact O-CD1 3.26Å; Y67-I154 HydrophobicContact CD1-CD1 3.99Å; Y67-I154 HydrophobicContact CE1-CD1 4.31Å; Y67-I154 HydrophobicContact CG-CD1 4.33Å; Y72-I154 HydrophobicContact CD2-CD1 4.41Å; Y72-I154 HydrophobicContact CD2-CG2 3.97Å; Y72-I154 HydrophobicContact CE2-CG2 4Å; P101-I154 HydrophobicContact CB-CD1 3.95Å; P101-I154 HydrophobicContact CG-CD1 3.66Å; P101-I154 HydrophobicContact CG-CG1 4.15Å; E152-I154 HydrophobicContact CG-CG2 4.19Å; E152-I154 WeakPolarHBondContact OE1-CG2 3.31Å; I154-H158 WeakPolarHBondContact O-CA 3.29Å; I154-H158 PolarHBondContact O-N 3.28Å; I154-V159 HydrophobicContact CG1-CB 3.98Å; I154-V159 PolarHBondContact N-O 2.87Å; I154-V159 PolarHBondContact O-N 3.12Å; I154-V161 HydrophobicContact CG2-CG2 3.76Å
155G98Very high98Very high39 Ų3961 Ų6140%0.40233%0.329SS..THydrogen-bonded Turntrans71.2-178.317500000115D66 N157 H158D66-G155 WeakPolarHBondContact OD1-CA 3.34Å; G155-N157 VanDerWaalsContact C-N 3.25Å; G155-N157 PolarHBondContact O-N 3.44Å; G155-H158 PolarHBondContact O-N 2.89Å
156K97.1Very high98.1Very high195 Ų19559.4 Ų59.485%0.84831%0.312SS*.THydrogen-bonded Turntrans-72.5-23.3-179.5-68.4-173.4178.7-177.60112.2D66 H158D66-K156 PolarHBondContact OD1-N 2.83Å; K156-H158 VanDerWaalsContact C-N 3.31Å
157N97.7Very high98.1Very high47 Ų4752.6 Ų52.625%0.25128%0.283SS..THydrogen-bonded Turntrans-91.16.6178.7-57.2-61.1000112.8D66 G155 V159D66-N157 VanDerWaalsContact CG-ND2 3.34Å; D66-N157 PolarHBondContact OD1-N 3.15Å; D66-N157 VanDerWaalsContact OD1-N 3.13Å; D66-N157 PolarHBondContact OD1-ND2 3.15Å; D66-N157 VanDerWaalsContact OD1-ND2 3.15Å; D66-N157 PolarHBondContact OD2-ND2 3.04Å; G155-N157 VanDerWaalsContact C-N 3.25Å; G155-N157 PolarHBondContact O-N 3.44Å; N157-V159 VanDerWaalsContact C-N 3.34Å; N157-V159 HydrophobicContact CB-CG2 4.49Å; N157-V159 PolarHBondContact O-N 2.82Å
158H97.4Very high98.2Very high128 Ų12847.4 Ų47.459%0.59326%0.255SS*.THydrogen-bonded Turntrans49.649.9177.3-56.5143.2000113.3V153 I154 G155 K156 A160V153-H158 HydrophobicContact CB-CB 3.97Å; V153-H158 HydrophobicContact CG1-CB 4.41Å; V153-H158 HydrophobicContact CG2-CB 4.07Å; I154-H158 WeakPolarHBondContact O-CA 3.29Å; I154-H158 PolarHBondContact O-N 3.28Å; G155-H158 PolarHBondContact O-N 2.89Å; K156-H158 VanDerWaalsContact C-N 3.31Å; H158-A160 PolarHBondContact O-N 3.01Å
159V98.4Very high98.3Very high1 Ų145.2 Ų45.21%0.00624%0.241CC..EExtended strand (participates in β ladder)trans-66.5119.8179-176.40000108.7D66 P101 V153 I154 N157D66-V159 HydrophobicContact CB-CG2 3.97Å; P101-V159 HydrophobicContact CG-CG1 3.87Å; V153-V159 CarbonylContact C-O 3.43Å; V153-V159 WeakPolarHBondContact CA-O 3.28Å; I154-V159 HydrophobicContact CG1-CB 3.98Å; I154-V159 PolarHBondContact N-O 2.87Å; I154-V159 PolarHBondContact O-N 3.12Å; N157-V159 VanDerWaalsContact C-N 3.34Å; N157-V159 HydrophobicContact CB-CG2 4.49Å; N157-V159 PolarHBondContact O-N 2.82Å
160A98.5Very high98.3Very high15 Ų1541.6 Ų41.612%0.12422%0.219CC..EExtended strand (participates in β ladder)trans-68134.5-17700000111.9P101 Y137 F151 H158 P162P101-A160 VanDerWaalsContact CD-O 3.3Å; P101-A160 WeakPolarHBondContact CD-O 3.41Å; Y137-A160 HydrophobicContact CE1-CB 3.89Å; Y137-A160 WeakPolarHBondContact OH-CB 3.47Å; F151-A160 HydrophobicContact CD2-CB 3.95Å; F151-A160 HydrophobicContact CE2-CB 3.71Å; H158-A160 PolarHBondContact O-N 3.01Å; A160-P162 WeakPolarHBondContact O-CD 3.47Å
161V98.7Very high98.4Very high9 Ų937 Ų376%0.05519%0.19CC..  trans-90.4108.6173-178.40000108.8Y72 P101 F151 E152 I154Y72-V161 HydrophobicContact CD1-CG1 4.07Å; Y72-V161 HydrophobicContact CD2-CG2 4.18Å; Y72-V161 HydrophobicContact CE1-CG1 3.46Å; Y72-V161 VanDerWaalsContact CE1-CG1 3.46Å; Y72-V161 HydrophobicContact CE1-CG2 4.46Å; Y72-V161 HydrophobicContact CE2-CG1 4.27Å; Y72-V161 HydrophobicContact CE2-CG2 3.8Å; P101-V161 HydrophobicContact CB-CB 4.26Å; P101-V161 HydrophobicContact CB-CG1 4.22Å; P101-V161 HydrophobicContact CB-CG2 3.82Å; P101-V161 HydrophobicContact CG-CG2 4.09Å; F151-V161 WeakPolarHBondContact CB-O 3.42Å; E152-V161 HydrophobicContact CB-CB 4.12Å; E152-V161 HydrophobicContact CB-CG2 3.9Å; E152-V161 HydrophobicContact CG-CG2 4.13Å; E152-V161 WeakPolarHBondContact O-CB 3.36Å; E152-V161 WeakPolarHBondContact O-CG2 3.38Å; E152-V161 PolarHBondContact O-N 3.2Å; I154-V161 HydrophobicContact CG2-CG2 3.76Å
162P98.7Very high98.4Very high2 Ų233.1 Ų33.11%0.01317%0.174CC..  trans-62.2145.4-178.3-25.238000112.1A100 P135 Y137 A160 H164 F165 N187A100-P162 HydrophobicContact CB-CG 4.17Å; P135-P162 HydrophobicContact CB-CB 3.54Å; P135-P162 HydrophobicContact CB-CG 3.34Å; P135-P162 HydrophobicContact CG-CG 4.49Å; Y137-P162 HydrophobicContact CE1-CB 4.26Å; Y137-P162 HydrophobicContact CE1-CG 4.35Å; A160-P162 WeakPolarHBondContact O-CD 3.47Å; P162-H164 WeakPolarHBondContact CB-O 3.32Å; P162-F165 HydrophobicContact CB-CE1 4.12Å; P162-F165 HydrophobicContact CB-CE2 4Å; P162-F165 HydrophobicContact CB-CZ 3.74Å; P162-F165 HydrophobicContact CG-CE1 3.81Å; P162-F165 HydrophobicContact CG-CE2 4.23Å; P162-F165 HydrophobicContact CG-CZ 3.5Å; P162-N187 WeakPolarHBondContact O-CB 3.34Å; P162-N187 PolarHBondContact O-ND2 2.9Å
163T98.7Very high98.3Very high30 Ų3029.4 Ų29.418%0.18416%0.158CC..SBendtrans-76.6-32.5175.170.10000110.9L136 L138 F151 N187L136-T163 PolarHBondContact O-N 3.32Å; L136-T163 PolarHBondContact O-OG1 3.41Å; L138-T163 PolarHBondContact N-OG1 2.98Å; F151-T163 HydrophobicContact CB-CG2 4.23Å; T163-N187 WeakPolarHBondContact O-CB 3.32Å; T163-N187 PolarHBondContact O-N 2.93Å
164H98.8Very high98.1Very high49 Ų4930.3 Ų30.323%0.22717%0.172CC..EExtended strand (participates in β ladder)trans-142.7167178.5-61.869.4000110.3L136 L138 P162 V184 L185 P186L136-H164 HydrophobicContact CB-CB 4.12Å; L136-H164 PolarHBondContact N-O 2.96Å; L136-H164 PolarHBondContact O-N 3.26Å; L136-H164 VanDerWaalsContact O-N 3.15Å; L138-H164 HydrophobicContact CD1-CB 4.22Å; L138-H164 HydrophobicContact CG-CB 4.47Å; P162-H164 WeakPolarHBondContact CB-O 3.32Å; H164-V184 HydrophobicContact CB-CG1 4.07Å; H164-L185 CarbonylContact C-O 3.52Å; H164-L185 WeakPolarHBondContact CA-O 3.47Å; H164-L185 VanDerWaalsContact CB-O 3.3Å; H164-L185 WeakPolarHBondContact CB-O 3.5Å; H164-P186 WeakPolarHBondContact CD2-CA 3.47Å
165F98.9Very high97.8Very high0 Ų034.2 Ų34.20%019%0.193CC..EExtended strand (participates in β ladder)trans-126.8146.3167.6-68.5-89.5000109.7L77 A100 Q102 F107 W112 G134 P135 P162 V184 L185 N187L77-F165 HydrophobicContact CD2-CD1 3.81Å; L77-F165 HydrophobicContact CD2-CE1 3.77Å; A100-F165 HydrophobicContact CB-CE1 3.47Å; A100-F165 VanDerWaalsContact CB-CE1 3.47Å; A100-F165 HydrophobicContact CB-CZ 3.64Å; Q102-F165 HydrophobicContact CG-CD2 4.39Å; Q102-F165 HydrophobicContact CG-CE1 4.24Å; Q102-F165 HydrophobicContact CG-CE2 3.56Å; Q102-F165 HydrophobicContact CG-CZ 3.46Å; Q102-F165 VanDerWaalsContact CG-CZ 3.46Å; F107-F165 AromaticContact CE1-CD2 3.6Å; F107-F165 HydrophobicContact CE1-CD2 3.6Å; F107-F165 AromaticContact CE1-CE2 3.88Å; F107-F165 HydrophobicContact CE1-CE2 3.88Å; F107-F165 HydrophobicContact CZ-CB 4.38Å; F107-F165 AromaticContact CZ-CD2 3.59Å; F107-F165 HydrophobicContact CZ-CD2 3.59Å; F107-F165 HydrophobicContact CZ-CE2 4.33Å; F107-F165 HydrophobicContact CZ-CG 4.32Å; W112-F165 HydrophobicContact CE3-CB 4.3Å; W112-F165 HydrophobicContact CH2-CB 3.53Å; W112-F165 HydrophobicContact CH2-CG 4.45Å; W112-F165 HydrophobicContact CZ2-CB 4.23Å; W112-F165 HydrophobicContact CZ3-CB 3.57Å; G134-F165 WeakPolarHBondContact O-CA 3.4Å; P135-F165 HydrophobicContact CB-CD1 4.36Å; P135-F165 HydrophobicContact CB-CE1 4.14Å; P162-F165 HydrophobicContact CB-CE1 4.12Å; P162-F165 HydrophobicContact CB-CE2 4Å; P162-F165 HydrophobicContact CB-CZ 3.74Å; P162-F165 HydrophobicContact CG-CE1 3.81Å; P162-F165 HydrophobicContact CG-CE2 4.23Å; P162-F165 HydrophobicContact CG-CZ 3.5Å; F165-V184 WeakPolarHBondContact O-CA 3.43Å; F165-L185 PolarHBondContact N-O 3.24Å; F165-L185 PolarHBondContact O-N 3.37Å; F165-N187 HydrophobicContact CD2-CB 4.16Å; F165-N187 HydrophobicContact CE2-CB 3.88Å
166F98.9Very high97.6Very high0 Ų035.2 Ų35.20%019%0.194CC..EExtended strand (participates in β ladder)trans-111.4154.6172.276.3-95.9000111.5W27 C132 T133 G134 L136 V168 Y183 V184 I206 A210 F212 I214W27-F166 HydrophobicContact CB-CZ 4.34Å; C132-F166 HydrophobicContact CB-CE2 4.3Å; T133-F166 WeakPolarHBondContact CA-O 3.25Å; T133-F166 WeakPolarHBondContact CG2-O 3.3Å; G134-F166 PolarHBondContact N-O 3.32Å; G134-F166 WeakPolarHBondContact O-CD1 3.44Å; G134-F166 PolarHBondContact O-N 3.1Å; L136-F166 HydrophobicContact CD1-CB 4.08Å; L136-F166 HydrophobicContact CD1-CD1 4.36Å; L136-F166 HydrophobicContact CD2-CD1 3.87Å; L136-F166 HydrophobicContact CD2-CE1 4.42Å; L136-F166 HydrophobicContact CG-CB 4.46Å; L136-F166 HydrophobicContact CG-CD1 3.88Å; F166-V168 HydrophobicContact CD2-CG2 4.02Å; F166-V168 HydrophobicContact CE2-CG2 4.47Å; F166-Y183 CarbonylContact C-O 3.58Å; F166-Y183 WeakPolarHBondContact CA-O 3.44Å; F166-Y183 WeakPolarHBondContact CB-O 3.46Å; F166-V184 HydrophobicContact CB-CG2 4.31Å; F166-I206 HydrophobicContact CB-CD1 4.2Å; F166-I206 HydrophobicContact CB-CG1 4.4Å; F166-I206 HydrophobicContact CB-CG2 3.83Å; F166-I206 HydrophobicContact CD1-CG2 4.01Å; F166-I206 HydrophobicContact CD2-CG2 3.81Å; F166-I206 HydrophobicContact CE2-CG2 4.38Å; F166-I206 HydrophobicContact CG-CG2 3.6Å; F166-A210 HydrophobicContact CE1-CB 4.38Å; F166-F212 HydrophobicContact CE1-CE2 4.19Å; F166-F212 AromaticContact CE1-CZ 3.8Å; F166-F212 HydrophobicContact CE1-CZ 3.8Å; F166-F212 AromaticContact CZ-CE2 3.73Å; F166-F212 HydrophobicContact CZ-CE2 3.73Å; F166-F212 AromaticContact CZ-CZ 3.68Å; F166-F212 HydrophobicContact CZ-CZ 3.68Å; F166-I214 HydrophobicContact CD2-CD1 4.43Å; F166-I214 HydrophobicContact CE2-CD1 3.9Å; F166-I214 HydrophobicContact CZ-CD1 4.38Å
167K98.9Very high97.4Very high1 Ų132 Ų320%0.00418%0.176CC..EExtended strand (participates in β ladder)trans-141.5124.6164.7-166.3172.9-68-76.40109.1W112 L115 V119 V131 C132 T133 Y183W112-K167 HydrophobicContact CH2-CB 4.24Å; L115-K167 HydrophobicContact CD2-CB 3.95Å; L115-K167 HydrophobicContact CD2-CD 4.21Å; L115-K167 HydrophobicContact CG-CD 4.12Å; V119-K167 HydrophobicContact CG2-CD 3.79Å; V131-K167 HydrophobicContact CG1-CD 3.93Å; V131-K167 HydrophobicContact CG1-CG 3.61Å; C132-K167 CarbonylContact O-C 3.49Å; C132-K167 WeakPolarHBondContact O-CA 3.36Å; T133-K167 PolarHBondContact OG1-NZ 2.78Å; K167-Y183 PolarHBondContact N-O 3.32Å; K167-Y183 PolarHBondContact O-N 3.38Å
168V98.8Very high97.4Very high0 Ų030.8 Ų30.80%017%0.168CC..EExtended strand (participates in β ladder)trans-116.6117.8176.1-1720000108.4V131 C132 F166 L180 E181 L203 I206 I214 F215V131-V168 CarbonylContact C-O 3.47Å; V131-V168 WeakPolarHBondContact CA-O 3.46Å; C132-V168 HydrophobicContact CB-CB 4.47Å; C132-V168 PolarHBondContact N-O 3.31Å; C132-V168 PolarHBondContact O-N 3.47Å; F166-V168 HydrophobicContact CD2-CG2 4.02Å; F166-V168 HydrophobicContact CE2-CG2 4.47Å; V168-L180 HydrophobicContact CG1-CD1 3.85Å; V168-L180 HydrophobicContact CG1-CD2 3.96Å; V168-L180 HydrophobicContact CG1-CG 3.95Å; V168-E181 CarbonylContact C-O 3.6Å; V168-E181 WeakPolarHBondContact CA-O 3.47Å; V168-L203 HydrophobicContact CB-CD1 4.46Å; V168-L203 HydrophobicContact CG1-CD1 3.72Å; V168-L203 HydrophobicContact CG2-CD1 3.91Å; V168-I206 HydrophobicContact CG2-CD1 3.75Å; V168-I206 HydrophobicContact CG2-CG2 4.47Å; V168-I214 HydrophobicContact CB-CG2 4.2Å; V168-I214 HydrophobicContact CG1-CG2 4.18Å; V168-I214 HydrophobicContact CG2-CD1 3.82Å; V168-F215 HydrophobicContact CB-CE2 4.3Å; V168-F215 HydrophobicContact CG1-CD2 4.22Å; V168-F215 HydrophobicContact CG1-CE2 3.72Å
169A98.8Very high97.4Very high0 Ų026 Ų260%015%0.146CC..EExtended strand (participates in β ladder)trans-108.9118.9177.200000110V119 V129 Y130 L180 E181V119-A169 HydrophobicContact CG2-CB 4.46Å; V129-A169 HydrophobicContact CG1-CB 4.36Å; Y130-A169 CarbonylContact O-C 3.58Å; Y130-A169 WeakPolarHBondContact O-CA 3.18Å; A169-L180 WeakPolarHBondContact O-CA 3.47Å; A169-E181 PolarHBondContact N-O 3.02Å; A169-E181 PolarHBondContact O-N 3.05Å
170L98.5Very high97.4Very high0 Ų026.1 Ų26.10%015%0.146CC..EExtended strand (participates in β ladder)trans-99.7120.8169.5172.767000108.9F3 V129 Y130 W178 F215 L218 L223F3-L170 HydrophobicContact CD2-CD2 3.49Å; F3-L170 VanDerWaalsContact CD2-CD2 3.49Å; F3-L170 HydrophobicContact CE2-CD2 3.69Å; F3-L170 HydrophobicContact CG-CD2 3.99Å; F3-L170 HydrophobicContact CZ-CD2 4.37Å; V129-L170 CarbonylContact C-O 3.59Å; V129-L170 WeakPolarHBondContact CA-O 3.42Å; Y130-L170 PolarHBondContact N-O 2.78Å; Y130-L170 PolarHBondContact O-N 3.14Å; L170-W178 HydrophobicContact CD1-CB 4.42Å; L170-W178 HydrophobicContact CD1-CE3 3.71Å; L170-W178 HydrophobicContact CD1-CZ3 4.41Å; L170-W178 HydrophobicContact CD2-CE3 4.01Å; L170-W178 HydrophobicContact CD2-CZ3 3.94Å; L170-W178 HydrophobicContact CG-CE3 3.64Å; L170-W178 HydrophobicContact CG-CZ3 3.84Å; L170-F215 HydrophobicContact CB-CD2 3.64Å; L170-F215 HydrophobicContact CB-CE1 4.42Å; L170-F215 HydrophobicContact CB-CE2 3.41Å; L170-F215 VanDerWaalsContact CB-CE2 3.41Å; L170-F215 HydrophobicContact CB-CG 4.25Å; L170-F215 HydrophobicContact CB-CZ 3.85Å; L170-F215 HydrophobicContact CD2-CB 4.23Å; L170-F215 HydrophobicContact CD2-CD1 4.24Å; L170-F215 HydrophobicContact CD2-CD2 4.13Å; L170-F215 HydrophobicContact CD2-CG 3.94Å; L170-F215 HydrophobicContact CG-CD2 4.42Å; L170-L218 HydrophobicContact CD1-CD2 3.44Å; L170-L218 VanDerWaalsContact CD1-CD2 3.44Å; L170-L218 HydrophobicContact CD2-CD2 3.81Å; L170-L218 HydrophobicContact CG-CD2 4.26Å; L170-L223 HydrophobicContact CD1-CD2 3.7Å
171V98.6Very high97.4Very high0 Ų026.4 Ų26.40%015%0.145CC..EExtended strand (participates in β ladder)trans-117.6127.6-169.4-1760000110.6L122 N126 V129 W178 F179L122-V171 HydrophobicContact CD1-CG2 4.15Å; N126-V171 HydrophobicContact CB-CG1 3.43Å; N126-V171 VanDerWaalsContact CB-CG1 3.43Å; V129-V171 HydrophobicContact CG1-CG2 4.21Å; V129-V171 HydrophobicContact CG2-CB 4.43Å; V129-V171 HydrophobicContact CG2-CG1 3.99Å; V129-V171 HydrophobicContact CG2-CG2 4.11Å; V171-W178 CarbonylContact O-C 3.57Å; V171-W178 VanDerWaalsContact O-CA 3.25Å; V171-W178 WeakPolarHBondContact O-CA 3.46Å; V171-F179 HydrophobicContact CB-CD1 3.92Å; V171-F179 HydrophobicContact CB-CD2 4.06Å; V171-F179 HydrophobicContact CB-CE1 3.54Å; V171-F179 HydrophobicContact CB-CE2 3.7Å; V171-F179 HydrophobicContact CB-CG 4.18Å; V171-F179 HydrophobicContact CB-CZ 3.43Å; V171-F179 VanDerWaalsContact CB-CZ 3.43Å; V171-F179 HydrophobicContact CG1-CD1 4.11Å; V171-F179 HydrophobicContact CG1-CE1 3.31Å; V171-F179 HydrophobicContact CG1-CE2 4.12Å; V171-F179 HydrophobicContact CG1-CZ 3.33Å; V171-F179 HydrophobicContact CG2-CD2 4.18Å; V171-F179 HydrophobicContact CG2-CE1 4.33Å; V171-F179 HydrophobicContact CG2-CE2 3.6Å; V171-F179 HydrophobicContact CG2-CZ 3.7Å; V171-F179 PolarHBondContact N-O 2.8Å; V171-F179 PolarHBondContact O-N 3.01Å
172E98Very high97.4Very high8 Ų826 Ų264%0.03714%0.142CC..EExtended strand (participates in β ladder)trans-99114.6170.2-166.6-179.9167.100109.4N126 K127 N128 R177 W178N126-E172 WeakPolarHBondContact CB-O 3.42Å; K127-E172 WeakPolarHBondContact CB-O 3.41Å; K127-E172 HydrophobicContact CD-CG 4.31Å; K127-E172 WeakPolarHBondContact CD-OE1 3.18Å; K127-E172 WeakPolarHBondContact CE-OE1 3.48Å; K127-E172 PolarHBondContact N-O 2.69Å; K127-E172 IonicContact NZ-OE1 2.79Å; K127-E172 PolarHBondContact NZ-OE1 2.88Å; N128-E172 HydrophobicContact CB-CB 3.98Å; N128-E172 PolarHBondContact N-O 3.27Å; N128-E172 PolarHBondContact ND2-OE2 3.34Å; N128-E172 PolarHBondContact O-N 3.15Å; E172-R177 CarbonylContact C-O 3.53Å; E172-R177 WeakPolarHBondContact CA-O 3.38Å; E172-W178 HydrophobicContact CB-CD2 4.12Å; E172-W178 HydrophobicContact CB-CE3 3.86Å; E172-W178 HydrophobicContact CB-CH2 3.54Å; E172-W178 HydrophobicContact CB-CZ2 3.8Å; E172-W178 HydrophobicContact CB-CZ3 3.6Å; E172-W178 HydrophobicContact CG-CD2 4.2Å; E172-W178 HydrophobicContact CG-CE3 4.42Å; E172-W178 HydrophobicContact CG-CH2 3.8Å; E172-W178 HydrophobicContact CG-CZ2 3.5Å; E172-W178 HydrophobicContact CG-CZ3 4.27Å; E172-W178 VanDerWaalsContact OE2-CH2 3.23Å; E172-W178 WeakPolarHBondContact OE2-CH2 3.46Å; E172-W178 VanDerWaalsContact OE2-CZ2 3.28Å; E172-W178 WeakPolarHBondContact OE2-CZ2 3.34Å
173T96.4Very high97.4Very high19 Ų1926 Ų2612%0.11714%0.142CC..  trans-68.8168175.456.90000111.5D175 S176 R177 F179T173-D175 VanDerWaalsContact CB-OD1 3.24Å; T173-D175 WeakPolarHBondContact CB-OD1 3.47Å; T173-D175 PolarHBondContact O-N 3.31Å; T173-D175 PolarHBondContact OG1-OD1 3.13Å; T173-S176 PolarHBondContact O-N 3.43Å; T173-R177 PolarHBondContact N-O 2.76Å; T173-R177 WeakPolarHBondContact OG1-CA 3.29Å; T173-R177 WeakPolarHBondContact OG1-CB 3.44Å; T173-R177 PolarHBondContact OG1-N 2.96Å; T173-R177 PolarHBondContact OG1-O 2.94Å; T173-F179 HydrophobicContact CG2-CD1 3.96Å; T173-F179 HydrophobicContact CG2-CE1 3.84Å
174A93.4Very high97.5Very high87 Ų8725.9 Ų25.972%0.71914%0.141SC*.THydrogen-bonded Turntrans-58.4-34.3178.800000113.1S176A174-S176 PolarHBondContact O-N 2.92Å
175D93.3Very high97.5Very high89 Ų8923.5 Ų23.548%0.47613%0.131SC..THydrogen-bonded Turntrans-86.117.4175.161.7-8.4000113.5T173 R177T173-D175 VanDerWaalsContact CB-OD1 3.24Å; T173-D175 WeakPolarHBondContact CB-OD1 3.47Å; T173-D175 PolarHBondContact O-N 3.31Å; T173-D175 PolarHBondContact OG1-OD1 3.13Å; D175-R177 VanDerWaalsContact C-N 3.28Å; D175-R177 VanDerWaalsContact CG-NE 3.29Å; D175-R177 PolarHBondContact O-N 3.17Å; D175-R177 IonicContact OD1-CZ 3.58Å; D175-R177 IonicContact OD1-NE 3.03Å; D175-R177 PolarHBondContact OD1-NE 3.03Å; D175-R177 IonicContact OD1-NH2 2.69Å; D175-R177 IonicContact OD2-CZ 3.8Å; D175-R177 IonicContact OD2-NE 3.81Å; D175-R177 PolarHBondContact OD2-NE 3.33Å; D175-R177 IonicContact OD2-NH2 3.78Å; D175-R177 PolarHBondContact OD2-NH2 3.41Å
176S92.6Very high97.4Very high59 Ų5924.4 Ų24.441%0.41314%0.136SC..SBendtrans61.528.8174-49.30000114.9K127 T173 A174K127-S176 PolarHBondContact NZ-OG 3.08Å; T173-S176 PolarHBondContact O-N 3.43Å; A174-S176 PolarHBondContact O-N 2.92Å
177R94.4Very high97.4Very high127 Ų12725.2 Ų25.248%0.47914%0.141SC..  trans-90.4156.8166.2-60.9-178.1-69.5162.1-9.8110.1E172 T173 D175 I224E172-R177 CarbonylContact C-O 3.53Å; E172-R177 WeakPolarHBondContact CA-O 3.38Å; T173-R177 PolarHBondContact N-O 2.76Å; T173-R177 WeakPolarHBondContact OG1-CA 3.29Å; T173-R177 WeakPolarHBondContact OG1-CB 3.44Å; T173-R177 PolarHBondContact OG1-N 2.96Å; T173-R177 PolarHBondContact OG1-O 2.94Å; D175-R177 VanDerWaalsContact C-N 3.28Å; D175-R177 VanDerWaalsContact CG-NE 3.29Å; D175-R177 PolarHBondContact O-N 3.17Å; D175-R177 IonicContact OD1-CZ 3.58Å; D175-R177 IonicContact OD1-NE 3.03Å; D175-R177 PolarHBondContact OD1-NE 3.03Å; D175-R177 IonicContact OD1-NH2 2.69Å; D175-R177 IonicContact OD2-CZ 3.8Å; D175-R177 IonicContact OD2-NE 3.81Å; D175-R177 PolarHBondContact OD2-NE 3.33Å; D175-R177 IonicContact OD2-NH2 3.78Å; D175-R177 PolarHBondContact OD2-NH2 3.41Å; R177-I224 HydrophobicContact CB-CD1 3.89Å; R177-I224 HydrophobicContact CB-CG1 4.37Å; R177-I224 HydrophobicContact CB-CG2 3.94Å; R177-I224 HydrophobicContact CG-CG2 4.28Å
178W97.3Very high97.4Very high23 Ų2332.9 Ų32.99%0.08717%0.169CC..EExtended strand (participates in β ladder)trans-120134.6-173.8-62.482.5000112.2F3 Y130 L170 V171 E172 L218 C222 L223 I224F3-W178 HydrophobicContact CE1-CH2 4.47Å; F3-W178 AromaticContact CE2-CH2 3.59Å; F3-W178 HydrophobicContact CE2-CH2 3.59Å; F3-W178 AromaticContact CE2-CZ3 3.68Å; F3-W178 HydrophobicContact CE2-CZ3 3.68Å; F3-W178 AromaticContact CZ-CH2 3.3Å; F3-W178 HydrophobicContact CZ-CH2 3.3Å; F3-W178 AromaticContact CZ-CZ2 3.81Å; F3-W178 HydrophobicContact CZ-CZ2 3.81Å; F3-W178 AromaticContact CZ-CZ3 3.75Å; F3-W178 HydrophobicContact CZ-CZ3 3.75Å; Y130-W178 HydrophobicContact CD2-CZ3 4.1Å; Y130-W178 AromaticContact CE2-CH2 3.92Å; Y130-W178 HydrophobicContact CE2-CH2 3.92Å; Y130-W178 AromaticContact CE2-CZ3 3.96Å; Y130-W178 HydrophobicContact CE2-CZ3 3.96Å; L170-W178 HydrophobicContact CD1-CB 4.42Å; L170-W178 HydrophobicContact CD1-CE3 3.71Å; L170-W178 HydrophobicContact CD1-CZ3 4.41Å; L170-W178 HydrophobicContact CD2-CE3 4.01Å; L170-W178 HydrophobicContact CD2-CZ3 3.94Å; L170-W178 HydrophobicContact CG-CE3 3.64Å; L170-W178 HydrophobicContact CG-CZ3 3.84Å; V171-W178 CarbonylContact O-C 3.57Å; V171-W178 VanDerWaalsContact O-CA 3.25Å; V171-W178 WeakPolarHBondContact O-CA 3.46Å; E172-W178 HydrophobicContact CB-CD2 4.12Å; E172-W178 HydrophobicContact CB-CE3 3.86Å; E172-W178 HydrophobicContact CB-CH2 3.54Å; E172-W178 HydrophobicContact CB-CZ2 3.8Å; E172-W178 HydrophobicContact CB-CZ3 3.6Å; E172-W178 HydrophobicContact CG-CD2 4.2Å; E172-W178 HydrophobicContact CG-CE3 4.42Å; E172-W178 HydrophobicContact CG-CH2 3.8Å; E172-W178 HydrophobicContact CG-CZ2 3.5Å; E172-W178 HydrophobicContact CG-CZ3 4.27Å; E172-W178 VanDerWaalsContact OE2-CH2 3.23Å; E172-W178 WeakPolarHBondContact OE2-CH2 3.46Å; E172-W178 VanDerWaalsContact OE2-CZ2 3.28Å; E172-W178 WeakPolarHBondContact OE2-CZ2 3.34Å; W178-L218 HydrophobicContact CD2-CD1 4.29Å; W178-L218 HydrophobicContact CG-CD1 4.47Å; W178-C222 WeakPolarHBondContact CB-O 3.45Å; W178-L223 HydrophobicContact CB-CD2 3.96Å; W178-L223 CarbonylContact O-C 3.56Å; W178-L223 VanDerWaalsContact O-CA 3.26Å; W178-L223 WeakPolarHBondContact O-CA 3.35Å; W178-I224 VanDerWaalsContact O-CG1 3.26Å; W178-I224 WeakPolarHBondContact O-CG1 3.46Å; W178-I224 PolarHBondContact O-N 3.13Å
179F97.9Very high97.4Very high28 Ų2837.1 Ų37.112%0.12320%0.197CC..EExtended strand (participates in β ladder)trans-132.3159.5166.467.1-90.2000110.8L122 V171 T173 E181 I224 S225L122-F179 HydrophobicContact CD2-CE2 4.41Å; L122-F179 HydrophobicContact CD2-CZ 4.17Å; V171-F179 HydrophobicContact CB-CD1 3.92Å; V171-F179 HydrophobicContact CB-CD2 4.06Å; V171-F179 HydrophobicContact CB-CE1 3.54Å; V171-F179 HydrophobicContact CB-CE2 3.7Å; V171-F179 HydrophobicContact CB-CG 4.18Å; V171-F179 HydrophobicContact CB-CZ 3.43Å; V171-F179 VanDerWaalsContact CB-CZ 3.43Å; V171-F179 HydrophobicContact CG1-CD1 4.11Å; V171-F179 HydrophobicContact CG1-CE1 3.31Å; V171-F179 HydrophobicContact CG1-CE2 4.12Å; V171-F179 HydrophobicContact CG1-CZ 3.33Å; V171-F179 HydrophobicContact CG2-CD2 4.18Å; V171-F179 HydrophobicContact CG2-CE1 4.33Å; V171-F179 HydrophobicContact CG2-CE2 3.6Å; V171-F179 HydrophobicContact CG2-CZ 3.7Å; V171-F179 PolarHBondContact N-O 2.8Å; V171-F179 PolarHBondContact O-N 3.01Å; T173-F179 HydrophobicContact CG2-CD1 3.96Å; T173-F179 HydrophobicContact CG2-CE1 3.84Å; F179-E181 HydrophobicContact CD2-CG 4.3Å; F179-E181 HydrophobicContact CE2-CG 4.26Å; F179-I224 HydrophobicContact CB-CG1 4.33Å; F179-S225 WeakPolarHBondContact CA-O 3.4Å; F179-S225 VanDerWaalsContact CB-OG 3.27Å; F179-S225 WeakPolarHBondContact CB-OG 3.44Å
180L98.1Very high97.4Very high3 Ų338 Ų382%0.01620%0.202CC..EExtended strand (participates in β ladder)trans-125.1136.5-177.9-173.8142.4000110.8V168 A169 L203 F215 L223 S225 I226 N227V168-L180 HydrophobicContact CG1-CD1 3.85Å; V168-L180 HydrophobicContact CG1-CD2 3.96Å; V168-L180 HydrophobicContact CG1-CG 3.95Å; A169-L180 WeakPolarHBondContact O-CA 3.47Å; L180-L203 HydrophobicContact CD1-CD2 3.96Å; L180-L203 HydrophobicContact CD2-CB 4.41Å; L180-F215 HydrophobicContact CD1-CD2 3.98Å; L180-F215 HydrophobicContact CD1-CE2 4.45Å; L180-L223 HydrophobicContact CB-CD2 4.1Å; L180-S225 PolarHBondContact N-O 3.11Å; L180-I226 HydrophobicContact CD2-CG2 3.97Å; L180-I226 CarbonylContact O-C 3.49Å; L180-I226 WeakPolarHBondContact O-CA 3.47Å; L180-N227 PolarHBondContact O-N 2.89Å
181E98.7Very high97.3Very high20 Ų2043.2 Ų43.29%0.09323%0.23CC..EExtended strand (participates in β ladder)trans-121.6126.8169.3-66.3-177.1174.500109.3H118 L122 V168 A169 F179 Y183 Y200 N227H118-E181 IonicContact CD2-OE2 3.75Å; H118-E181 IonicContact CE1-OE2 2.83Å; H118-E181 IonicContact NE2-OE1 3.72Å; H118-E181 IonicContact NE2-OE2 3.82Å; H118-E181 PolarHBondContact NE2-OE2 3.24Å; L122-E181 WeakPolarHBondContact CD1-OE2 3.49Å; V168-E181 CarbonylContact C-O 3.6Å; V168-E181 WeakPolarHBondContact CA-O 3.47Å; A169-E181 PolarHBondContact N-O 3.02Å; A169-E181 PolarHBondContact O-N 3.05Å; F179-E181 HydrophobicContact CD2-CG 4.3Å; F179-E181 HydrophobicContact CE2-CG 4.26Å; E181-Y183 HydrophobicContact CB-CE2 3.7Å; E181-Y183 PolarHBondContact OE2-OH 2.89Å; E181-Y200 HydrophobicContact CB-CE1 4.17Å; E181-Y200 HydrophobicContact CG-CE1 4.26Å; E181-N227 WeakPolarHBondContact CA-OD1 3.43Å
182S98.7Very high97.2Very high0 Ų051.1 Ų51.10%026%0.26CS..EExtended strand (participates in β ladder)trans-128.2123.2-177.244.70000110.9Y200 A201 N227S182-Y200 WeakPolarHBondContact O-CA 3.49Å; S182-A201 WeakPolarHBondContact CB-O 3.2Å; S182-A201 PolarHBondContact O-N 2.77Å; S182-A201 PolarHBondContact OG-O 3.21Å; S182-N227 PolarHBondContact N-OD1 3.36Å; S182-N227 PolarHBondContact OG-ND2 2.87Å; S182-N227 VanDerWaalsContact OG-ND2 3.15Å; S182-N227 PolarHBondContact OG-OD1 3.19Å
183Y98.9Very high97.1Very high2 Ų254.7 Ų54.71%0.00829%0.291CS..EExtended strand (participates in β ladder)trans-120.6143.9-174.2-59.5-89.2000111.6L115 H118 F166 K167 E181 L196 F199 Y200L115-Y183 HydrophobicContact CD1-CD1 4.09Å; L115-Y183 HydrophobicContact CD1-CD2 3.58Å; L115-Y183 HydrophobicContact CD1-CE1 4.11Å; L115-Y183 HydrophobicContact CD1-CE2 3.58Å; L115-Y183 HydrophobicContact CD1-CG 3.81Å; L115-Y183 HydrophobicContact CD2-CD2 4.4Å; L115-Y183 HydrophobicContact CD2-CG 4.19Å; H118-Y183 PolarHBondContact CD2-OH 2.73Å; H118-Y183 PolarHBondContact NE2-OH 2.89Å; F166-Y183 CarbonylContact C-O 3.58Å; F166-Y183 WeakPolarHBondContact CA-O 3.44Å; F166-Y183 WeakPolarHBondContact CB-O 3.46Å; K167-Y183 PolarHBondContact N-O 3.32Å; K167-Y183 PolarHBondContact O-N 3.38Å; E181-Y183 HydrophobicContact CB-CE2 3.7Å; E181-Y183 PolarHBondContact OE2-OH 2.89Å; Y183-L196 HydrophobicContact CE1-CB 4.17Å; Y183-L196 WeakPolarHBondContact CE1-O 3.37Å; Y183-F199 VanDerWaalsContact CA-O 3.29Å; Y183-F199 WeakPolarHBondContact CA-O 3.29Å; Y183-F199 HydrophobicContact CD1-CB 4.32Å; Y183-Y200 AromaticContact CD1-CD1 3.83Å; Y183-Y200 HydrophobicContact CD1-CD1 3.83Å; Y183-Y200 HydrophobicContact CD1-CE1 4.11Å; Y183-Y200 AromaticContact CE1-CD1 3.48Å; Y183-Y200 HydrophobicContact CE1-CD1 3.48Å; Y183-Y200 VanDerWaalsContact CE1-CD1 3.48Å; Y183-Y200 AromaticContact CE1-CE1 3.31Å; Y183-Y200 HydrophobicContact CE1-CE1 3.31Å; Y183-Y200 HydrophobicContact CE2-CE1 4.08Å; Y183-Y200 HydrophobicContact CG-CD1 4.49Å; Y183-Y200 AromaticContact CZ-CD1 3.9Å; Y183-Y200 AromaticContact CZ-CE1 3.31Å; Y183-Y200 VanDerWaalsContact OH-CE1 3.31Å; Y183-Y200 WeakPolarHBondContact OH-CE1 3.27Å
184V98.9Very high97.2Very high28 Ų2854.8 Ų54.817%0.1729%0.294CS..EExtended strand (participates in β ladder)trans-129.9121.1166.7175.90000109L136 L138 H164 F165 F166 F199 A201 I206L136-V184 HydrophobicContact CD1-CG1 4.06Å; L136-V184 HydrophobicContact CD1-CG2 4.09Å; L138-V184 HydrophobicContact CD1-CG1 4.43Å; H164-V184 HydrophobicContact CB-CG1 4.07Å; F165-V184 WeakPolarHBondContact O-CA 3.43Å; F166-V184 HydrophobicContact CB-CG2 4.31Å; V184-F199 PolarHBondContact N-O 3.47Å; V184-A201 HydrophobicContact CB-CB 4.11Å; V184-A201 HydrophobicContact CG2-CB 3.64Å; V184-I206 HydrophobicContact CG2-CD1 3.9Å; V184-I206 HydrophobicContact CG2-CG1 3.53Å
185L98.8Very high97.4Very high0 Ų054.7 Ų54.70%029%0.286CS..EExtended strand (participates in β ladder)trans-120.1137.8179.4-70.178.7000110.6F107 K111 W112 L115 H164 F165 F199F107-L185 HydrophobicContact CE2-CB 3.79Å; F107-L185 HydrophobicContact CE2-CD2 4.28Å; F107-L185 HydrophobicContact CZ-CB 4.45Å; K111-L185 HydrophobicContact CG-CD2 3.88Å; W112-L185 HydrophobicContact CE3-CD2 4.31Å; W112-L185 HydrophobicContact CZ3-CD1 4.28Å; L115-L185 HydrophobicContact CD2-CD1 3.72Å; H164-L185 CarbonylContact C-O 3.52Å; H164-L185 WeakPolarHBondContact CA-O 3.47Å; H164-L185 VanDerWaalsContact CB-O 3.3Å; H164-L185 WeakPolarHBondContact CB-O 3.5Å; F165-L185 PolarHBondContact N-O 3.24Å; F165-L185 PolarHBondContact O-N 3.37Å; L185-F199 HydrophobicContact CD1-CB 3.89Å; L185-F199 HydrophobicContact CD1-CG 4.22Å; L185-F199 HydrophobicContact CD2-CD2 4.4Å; L185-F199 HydrophobicContact CD2-CG 4.41Å; L185-F199 HydrophobicContact CG-CB 4.01Å; L185-F199 HydrophobicContact CG-CD1 3.96Å; L185-F199 HydrophobicContact CG-CD2 4.27Å; L185-F199 HydrophobicContact CG-CG 3.8Å
186P98.7Very high97.7Very high18 Ų1851.3 Ų51.312%0.11727%0.268CS..EExtended strand (participates in β ladder)trans-73140.7175.732.3-35.7000110.9F107 H164 R188 V190F107-P186 WeakPolarHBondContact CD2-O 3.46Å; F107-P186 VanDerWaalsContact CE2-O 3.31Å; F107-P186 WeakPolarHBondContact CE2-O 3.25Å; H164-P186 WeakPolarHBondContact CD2-CA 3.47Å; P186-R188 HydrophobicContact CB-CG 3.87Å; P186-R188 HydrophobicContact CG-CG 3.9Å; P186-R188 PolarHBondContact O-N 3.37Å; P186-V190 HydrophobicContact CG-CG2 4.29Å
187N98.8Very high97.9Very high18 Ų1855.6 Ų55.610%0.09628%0.279CS..SBendtrans-77.267175.9-169.817.3000111P101 Q102 I103 P162 T163 F165P101-N187 PolarHBondContact O-ND2 3.22Å; Q102-N187 WeakPolarHBondContact CA-OD1 3.45Å; I103-N187 WeakPolarHBondContact CG1-O 3.37Å; I103-N187 PolarHBondContact N-OD1 2.82Å; P162-N187 WeakPolarHBondContact O-CB 3.34Å; P162-N187 PolarHBondContact O-ND2 2.9Å; T163-N187 WeakPolarHBondContact O-CB 3.32Å; T163-N187 PolarHBondContact O-N 2.93Å; F165-N187 HydrophobicContact CD2-CB 4.16Å; F165-N187 HydrophobicContact CE2-CB 3.88Å
188R98.5Very high98.1Very high161 Ų16153.1 Ų53.161%0.60828%0.281SS*.SBendtrans-151.2165.9-179.169-175.5178.2142.7-1.8109.3F107 P186 V190F107-R188 WeakPolarHBondContact CB-O 2.84Å; P186-R188 HydrophobicContact CB-CG 3.87Å; P186-R188 HydrophobicContact CG-CG 3.9Å; P186-R188 PolarHBondContact O-N 3.37Å; R188-V190 WeakPolarHBondContact O-CG2 3.39Å; R188-V190 PolarHBondContact O-N 2.89Å; R188-V190 VanDerWaalsContact O-N 3.17Å
189P98.5Very high98.1Very high90 Ų9053.5 Ų53.558%0.58428%0.284SS*.  trans-54.8125.5171.2-24.435.7000110.6I103I103-P189 HydrophobicContact CG2-CG 4.07Å
190V98.3Very high98.2Very high17 Ų1754.9 Ų54.910%0.10329%0.288CS..  trans-109.9138.5176.7-178.80000108.7G106 F107 K111 P186 R188 R192 A194 F199G106-V190 PolarHBondContact O-N 3.49Å; F107-V190 HydrophobicContact CD2-CG2 4.24Å; K111-V190 HydrophobicContact CB-CB 4.02Å; K111-V190 HydrophobicContact CB-CG1 4.3Å; K111-V190 HydrophobicContact CD-CG1 4.49Å; K111-V190 HydrophobicContact CG-CB 4.08Å; K111-V190 HydrophobicContact CG-CG1 3.84Å; P186-V190 HydrophobicContact CG-CG2 4.29Å; R188-V190 WeakPolarHBondContact O-CG2 3.39Å; R188-V190 PolarHBondContact O-N 2.89Å; R188-V190 VanDerWaalsContact O-N 3.17Å; V190-R192 PolarHBondContact O-N 2.96Å; V190-A194 HydrophobicContact CG1-CB 4.46Å; V190-F199 HydrophobicContact CG1-CE1 4.19Å; V190-F199 HydrophobicContact CG1-CE2 4.15Å; V190-F199 HydrophobicContact CG1-CZ 3.43Å; V190-F199 VanDerWaalsContact CG1-CZ 3.43Å
191D97.3Very high98.2Very high110 Ų11055.4 Ų55.459%0.58829%0.293SS*.  trans-57129.4174.7-175.6-0.4000110.4K111 A193 A194K111-D191 VanDerWaalsContact CE-O 3.27Å; K111-D191 WeakPolarHBondContact CE-O 3.3Å; D191-A193 PolarHBondContact O-N 2.9Å; D191-A193 PolarHBondContact OD1-N 3.37Å; D191-A194 HydrophobicContact CB-CB 4.44Å; D191-A194 WeakPolarHBondContact O-CB 3.42Å; D191-A194 PolarHBondContact O-N 2.69Å
192R94.9Very high98.1Very high166 Ų16657.8 Ų57.863%0.62631%0.31SS*.THydrogen-bonded Turntrans-61.7-31.7177.3-71.9-176.5173.2-172.1-1.7111.5D110 K111 V190 A194D110-R192 IonicContact OD1-CZ 3.34Å; D110-R192 IonicContact OD1-NE 3.4Å; D110-R192 PolarHBondContact OD1-NE 2.82Å; D110-R192 IonicContact OD1-NH2 2.69Å; D110-R192 PolarHBondContact OD1-NH2 2.89Å; D110-R192 IonicContact OD2-NH2 3.58Å; K111-R192 PolarHBondContact NZ-O 2.87Å; V190-R192 PolarHBondContact O-N 2.96Å; R192-A194 VanDerWaalsContact C-N 3.3Å; R192-A194 PolarHBondContact O-N 3.44Å
193A97.4Very high98Very high83 Ų8358.4 Ų58.469%0.68631%0.313SS*.THydrogen-bonded Turntrans-73.1-19179.400000113.7D191 P195D191-A193 PolarHBondContact O-N 2.9Å; D191-A193 PolarHBondContact OD1-N 3.37Å; A193-P195 WeakPolarHBondContact O-CD 3.43Å
194A98Very high97.9Very high22 Ų2261.3 Ų61.318%0.18233%0.327CS..SBendtrans-64.8122.3-179.200000111K111 V190 D191 R192 F199K111-A194 WeakPolarHBondContact CE-O 3.32Å; K111-A194 PolarHBondContact NZ-O 2.88Å; V190-A194 HydrophobicContact CG1-CB 4.46Å; D191-A194 HydrophobicContact CB-CB 4.44Å; D191-A194 WeakPolarHBondContact O-CB 3.42Å; D191-A194 PolarHBondContact O-N 2.69Å; R192-A194 VanDerWaalsContact C-N 3.3Å; R192-A194 PolarHBondContact O-N 3.44Å; A194-F199 HydrophobicContact CB-CE2 4.13Å; A194-F199 HydrophobicContact CB-CZ 4.07Å
195P98Very high97.9Very high85 Ų8563 Ų6355%0.55234%0.341SS*.  trans-70.8142.3-17828.6-34.5000111.2A193 K197 S198A193-P195 WeakPolarHBondContact O-CD 3.43Å; P195-K197 PolarHBondContact O-N 2.92Å; P195-S198 WeakPolarHBondContact O-CB 3.34Å; P195-S198 PolarHBondContact O-N 2.94Å; P195-S198 PolarHBondContact O-OG 2.91Å
196L98.4Very high97.9Very high18 Ų1863.1 Ų63.19%0.09434%0.341CS..G310 helixtrans-51.7-34.9179.5-71179.2000113.9K111 E114 L115 H118 Y183 S198 F199K111-L196 HydrophobicContact CD-CD2 3.91Å; E114-L196 HydrophobicContact CG-CD1 4.22Å; E114-L196 HydrophobicContact CG-CD2 4.4Å; E114-L196 HydrophobicContact CG-CG 4.34Å; L115-L196 HydrophobicContact CB-CD1 4.46Å; L115-L196 HydrophobicContact CB-CD2 3.9Å; L115-L196 HydrophobicContact CD1-CD1 4.34Å; L115-L196 HydrophobicContact CD1-CD2 4.49Å; H118-L196 HydrophobicContact CB-CD1 3.63Å; Y183-L196 HydrophobicContact CE1-CB 4.17Å; Y183-L196 WeakPolarHBondContact CE1-O 3.37Å; L196-S198 PolarHBondContact O-N 2.86Å; L196-F199 WeakPolarHBondContact O-CB 3.38Å; L196-F199 PolarHBondContact O-N 2.85Å
197K97.7Very high97.8Very high148 Ų14863.3 Ų63.364%0.64334%0.34SS*.G310 helixtrans-61.4-22.7178.8-63-172.6178.1-177.20113.7P195 F199 Y200P195-K197 PolarHBondContact O-N 2.92Å; K197-F199 PolarHBondContact O-N 2.85Å; K197-Y200 HydrophobicContact CB-CD2 4Å; K197-Y200 HydrophobicContact CB-CE2 3.82Å; K197-Y200 HydrophobicContact CD-CE2 4.21Å; K197-Y200 HydrophobicContact CG-CD2 4.39Å; K197-Y200 HydrophobicContact CG-CE2 3.7Å; K197-Y200 WeakPolarHBondContact O-CB 3.49Å; K197-Y200 WeakPolarHBondContact O-CD2 3.15Å; K197-Y200 PolarHBondContact O-N 3.31Å
198S97.9Very high97.8Very high75 Ų7572.6 Ų72.652%0.52437%0.374SS..G310 helixtrans-70.2-14.217569.40000112.9P195 L196P195-S198 WeakPolarHBondContact O-CB 3.34Å; P195-S198 PolarHBondContact O-N 2.94Å; P195-S198 PolarHBondContact O-OG 2.91Å; L196-S198 PolarHBondContact O-N 2.86Å
199F98.6Very high97.8Very high32 Ų3267 Ų6714%0.1436%0.362CS..G310 helixtrans-97.37.3175.9-56.3-72.9000113K111 Y183 V184 L185 V190 A194 L196 K197 A201K111-F199 HydrophobicContact CD-CE2 4.29Å; K111-F199 HydrophobicContact CG-CE2 4.4Å; Y183-F199 VanDerWaalsContact CA-O 3.29Å; Y183-F199 WeakPolarHBondContact CA-O 3.29Å; Y183-F199 HydrophobicContact CD1-CB 4.32Å; V184-F199 PolarHBondContact N-O 3.47Å; L185-F199 HydrophobicContact CD1-CB 3.89Å; L185-F199 HydrophobicContact CD1-CG 4.22Å; L185-F199 HydrophobicContact CD2-CD2 4.4Å; L185-F199 HydrophobicContact CD2-CG 4.41Å; L185-F199 HydrophobicContact CG-CB 4.01Å; L185-F199 HydrophobicContact CG-CD1 3.96Å; L185-F199 HydrophobicContact CG-CD2 4.27Å; L185-F199 HydrophobicContact CG-CG 3.8Å; V190-F199 HydrophobicContact CG1-CE1 4.19Å; V190-F199 HydrophobicContact CG1-CE2 4.15Å; V190-F199 HydrophobicContact CG1-CZ 3.43Å; V190-F199 VanDerWaalsContact CG1-CZ 3.43Å; A194-F199 HydrophobicContact CB-CE2 4.13Å; A194-F199 HydrophobicContact CB-CZ 4.07Å; L196-F199 WeakPolarHBondContact O-CB 3.38Å; L196-F199 PolarHBondContact O-N 2.85Å; K197-F199 PolarHBondContact O-N 2.85Å; F199-A201 PolarHBondContact O-N 3.05Å
200Y98.7Very high97.7Very high56 Ų5664 Ų6422%0.2235%0.345CS..BIsolated β-bridgetrans-58.9134.4171.8-77.4-33000110.8E181 S182 Y183 K197 N227E181-Y200 HydrophobicContact CB-CE1 4.17Å; E181-Y200 HydrophobicContact CG-CE1 4.26Å; S182-Y200 WeakPolarHBondContact O-CA 3.49Å; Y183-Y200 AromaticContact CD1-CD1 3.83Å; Y183-Y200 HydrophobicContact CD1-CD1 3.83Å; Y183-Y200 HydrophobicContact CD1-CE1 4.11Å; Y183-Y200 AromaticContact CE1-CD1 3.48Å; Y183-Y200 HydrophobicContact CE1-CD1 3.48Å; Y183-Y200 VanDerWaalsContact CE1-CD1 3.48Å; Y183-Y200 AromaticContact CE1-CE1 3.31Å; Y183-Y200 HydrophobicContact CE1-CE1 3.31Å; Y183-Y200 HydrophobicContact CE2-CE1 4.08Å; Y183-Y200 HydrophobicContact CG-CD1 4.49Å; Y183-Y200 AromaticContact CZ-CD1 3.9Å; Y183-Y200 AromaticContact CZ-CE1 3.31Å; Y183-Y200 VanDerWaalsContact OH-CE1 3.31Å; Y183-Y200 WeakPolarHBondContact OH-CE1 3.27Å; K197-Y200 HydrophobicContact CB-CD2 4Å; K197-Y200 HydrophobicContact CB-CE2 3.82Å; K197-Y200 HydrophobicContact CD-CE2 4.21Å; K197-Y200 HydrophobicContact CG-CD2 4.39Å; K197-Y200 HydrophobicContact CG-CE2 3.7Å; K197-Y200 WeakPolarHBondContact O-CB 3.49Å; K197-Y200 WeakPolarHBondContact O-CD2 3.15Å; K197-Y200 PolarHBondContact O-N 3.31Å; Y200-N227 HydrophobicContact CD1-CB 4Å; Y200-N227 WeakPolarHBondContact CD1-OD1 3.4Å; Y200-N227 HydrophobicContact CD2-CB 3.74Å; Y200-N227 HydrophobicContact CE1-CB 4.26Å; Y200-N227 HydrophobicContact CE2-CB 4Å; Y200-N227 WeakPolarHBondContact CE2-O 3.22Å; Y200-N227 HydrophobicContact CG-CB 3.75Å
201A98.2Very high97.7Very high14 Ų1466.5 Ų66.512%0.11637%0.374CS..  trans-131.4146.1176.100000109.5S182 V184 F199 L203 I206 N227S182-A201 WeakPolarHBondContact CB-O 3.2Å; S182-A201 PolarHBondContact O-N 2.77Å; S182-A201 PolarHBondContact OG-O 3.21Å; V184-A201 HydrophobicContact CB-CB 4.11Å; V184-A201 HydrophobicContact CG2-CB 3.64Å; F199-A201 PolarHBondContact O-N 3.05Å; A201-L203 PolarHBondContact O-N 3.05Å; A201-I206 HydrophobicContact CB-CD1 4.42Å; A201-I206 HydrophobicContact CB-CG1 4.37Å; A201-N227 PolarHBondContact O-ND2 3.3Å
202P97.2Very high97.7Very high71 Ų7162.6 Ų62.646%0.46135%0.352SS..  trans-55.7139.6169.3-21.933000110.8E204 S205 I206P202-E204 PolarHBondContact O-N 2.68Å; P202-S205 WeakPolarHBondContact O-CB 3.3Å; P202-S205 PolarHBondContact O-N 2.76Å; P202-S205 VanDerWaalsContact O-N 3.1Å; P202-I206 PolarHBondContact O-N 3.49Å
203L96.9Very high97.8Very high12 Ų1258.9 Ų58.96%0.06334%0.344CS..Hα-helixtrans-56.8-43.4178.4178.761.2000110.6V168 L180 A201 S205 I206 E207 I214V168-L203 HydrophobicContact CB-CD1 4.46Å; V168-L203 HydrophobicContact CG1-CD1 3.72Å; V168-L203 HydrophobicContact CG2-CD1 3.91Å; L180-L203 HydrophobicContact CD1-CD2 3.96Å; L180-L203 HydrophobicContact CD2-CB 4.41Å; A201-L203 PolarHBondContact O-N 3.05Å; L203-S205 PolarHBondContact O-N 3.17Å; L203-I206 WeakPolarHBondContact O-CA 3.31Å; L203-I206 WeakPolarHBondContact O-CB 3.32Å; L203-I206 PolarHBondContact O-N 2.72Å; L203-E207 HydrophobicContact CD1-CG 4.37Å; L203-E207 HydrophobicContact CG-CG 4.24Å; L203-E207 WeakPolarHBondContact O-CG 3.49Å; L203-E207 PolarHBondContact O-N 3.5Å; L203-I214 HydrophobicContact CD1-CB 4.12Å; L203-I214 HydrophobicContact CD1-CD1 4.33Å; L203-I214 HydrophobicContact CD1-CG2 4.48Å
204E96.6Very high97.8Very high64 Ų6455 Ų5530%0.29931%0.312SS..Hα-helixtrans-61-33.2-179.6-60.477.6-172.700112P202 I206 E207 R208 R220P202-E204 PolarHBondContact O-N 2.68Å; E204-I206 VanDerWaalsContact C-N 3.34Å; E204-E207 PolarHBondContact O-N 2.81Å; E204-R208 WeakPolarHBondContact O-CB 3.23Å; E204-R208 WeakPolarHBondContact O-CG 3.34Å; E204-R208 PolarHBondContact O-N 3.38Å; E204-R220 IonicContact OE1-CZ 2.61Å; E204-R220 IonicContact OE1-NH1 3.26Å; E204-R220 PolarHBondContact OE1-NH1 3.19Å; E204-R220 IonicContact OE1-NH2 3.86Å; E204-R220 PolarHBondContact OE1-NH2 3.32Å
205S97.7Very high97.8Very high64 Ų6454.6 Ų54.645%0.44831%0.306SS..Hα-helixtrans-68.2-37.2176.3-630000111.3P202 L203 A209P202-S205 WeakPolarHBondContact O-CB 3.3Å; P202-S205 PolarHBondContact O-N 2.76Å; P202-S205 VanDerWaalsContact O-N 3.1Å; L203-S205 PolarHBondContact O-N 3.17Å; S205-A209 VanDerWaalsContact O-CB 3.3Å; S205-A209 WeakPolarHBondContact O-CB 3.49Å; S205-A209 PolarHBondContact O-N 3.05Å; S205-A209 VanDerWaalsContact O-N 3.15Å
206I98.5Very high97.6Very high1 Ų155.3 Ų55.31%0.00530%0.302CS..Hα-helixtrans-67.6-49.2173.8-62171.3000109.7F166 V168 V184 A201 P202 L203 E204 R208 A209 A210 I214F166-I206 HydrophobicContact CB-CD1 4.2Å; F166-I206 HydrophobicContact CB-CG1 4.4Å; F166-I206 HydrophobicContact CB-CG2 3.83Å; F166-I206 HydrophobicContact CD1-CG2 4.01Å; F166-I206 HydrophobicContact CD2-CG2 3.81Å; F166-I206 HydrophobicContact CE2-CG2 4.38Å; F166-I206 HydrophobicContact CG-CG2 3.6Å; V168-I206 HydrophobicContact CG2-CD1 3.75Å; V168-I206 HydrophobicContact CG2-CG2 4.47Å; V184-I206 HydrophobicContact CG2-CD1 3.9Å; V184-I206 HydrophobicContact CG2-CG1 3.53Å; A201-I206 HydrophobicContact CB-CD1 4.42Å; A201-I206 HydrophobicContact CB-CG1 4.37Å; P202-I206 PolarHBondContact O-N 3.49Å; L203-I206 WeakPolarHBondContact O-CA 3.31Å; L203-I206 WeakPolarHBondContact O-CB 3.32Å; L203-I206 PolarHBondContact O-N 2.72Å; E204-I206 VanDerWaalsContact C-N 3.34Å; I206-R208 VanDerWaalsContact C-N 3.33Å; I206-R208 PolarHBondContact O-N 3.14Å; I206-A209 PolarHBondContact O-N 3.48Å; I206-A209 VanDerWaalsContact O-N 3.12Å; I206-A210 VanDerWaalsContact O-CB 3.25Å; I206-A210 WeakPolarHBondContact O-CB 3.41Å; I206-A210 PolarHBondContact O-N 3.01Å; I206-I214 HydrophobicContact CG2-CD1 3.9Å
207E98.3Very high97.5Very high22 Ų2259.5 Ų59.510%0.10332%0.324CS..Hα-helixtrans-58.2-44.6-179.4-67.9177.9136.200111.9L203 E204 A209 A210 G211 F212 L213 I214L203-E207 HydrophobicContact CD1-CG 4.37Å; L203-E207 HydrophobicContact CG-CG 4.24Å; L203-E207 WeakPolarHBondContact O-CG 3.49Å; L203-E207 PolarHBondContact O-N 3.5Å; E204-E207 PolarHBondContact O-N 2.81Å; E207-A209 VanDerWaalsContact C-N 3.35Å; E207-A209 PolarHBondContact O-N 3.27Å; E207-A210 PolarHBondContact O-N 3.33Å; E207-G211 PolarHBondContact O-N 3.25Å; E207-F212 VanDerWaalsContact CA-O 3.23Å; E207-F212 WeakPolarHBondContact CA-O 3.35Å; E207-F212 VanDerWaalsContact CB-O 3.27Å; E207-F212 WeakPolarHBondContact CB-O 3.39Å; E207-F212 WeakPolarHBondContact CG-O 3.25Å; E207-F212 PolarHBondContact O-N 2.69Å; E207-L213 HydrophobicContact CB-CD2 4.47Å; E207-L213 WeakPolarHBondContact OE1-CA 3.35Å; E207-I214 HydrophobicContact CG-CB 4.5Å; E207-I214 HydrophobicContact CG-CG1 4.3Å; E207-I214 PolarHBondContact OE1-N 3.4Å
208R98.1Very high97.2Very high214 Ų21453.3 Ų53.381%0.80830%0.298SS*.Hα-helixtrans-62.9-39.5175.6-75.1176.1-169.5-76.7-0.7112.8E204 I206E204-R208 WeakPolarHBondContact O-CB 3.23Å; E204-R208 WeakPolarHBondContact O-CG 3.34Å; E204-R208 PolarHBondContact O-N 3.38Å; I206-R208 VanDerWaalsContact C-N 3.33Å; I206-R208 PolarHBondContact O-N 3.14Å
209A97.9Very high96.5Very high44 Ų4452.9 Ų52.936%0.36429%0.294SS..Hα-helixtrans-76.6-32.7-179.100000113L136 L138 S205 I206 E207L136-A209 HydrophobicContact CD2-CB 3.98Å; L138-A209 HydrophobicContact CD2-CB 3.54Å; S205-A209 VanDerWaalsContact O-CB 3.3Å; S205-A209 WeakPolarHBondContact O-CB 3.49Å; S205-A209 PolarHBondContact O-N 3.05Å; S205-A209 VanDerWaalsContact O-N 3.15Å; I206-A209 PolarHBondContact O-N 3.48Å; I206-A209 VanDerWaalsContact O-N 3.12Å; E207-A209 VanDerWaalsContact C-N 3.35Å; E207-A209 PolarHBondContact O-N 3.27Å
210A97.5Very high95.7Very high26 Ų2658.2 Ų58.222%0.21531%0.313CS..Hα-helixtrans-88-21.7-176.800000113.1L136 F166 I206 E207 F212L136-A210 HydrophobicContact CD2-CB 3.7Å; F166-A210 HydrophobicContact CE1-CB 4.38Å; I206-A210 VanDerWaalsContact O-CB 3.25Å; I206-A210 WeakPolarHBondContact O-CB 3.41Å; I206-A210 PolarHBondContact O-N 3.01Å; E207-A210 PolarHBondContact O-N 3.33Å; A210-F212 HydrophobicContact CB-CD1 4.01Å; A210-F212 HydrophobicContact CB-CD2 4.06Å; A210-F212 HydrophobicContact CB-CE1 3.57Å; A210-F212 HydrophobicContact CB-CE2 3.65Å; A210-F212 HydrophobicContact CB-CG 4.25Å; A210-F212 HydrophobicContact CB-CZ 3.4Å; A210-F212 VanDerWaalsContact CB-CZ 3.4Å; A210-F212 VanDerWaalsContact O-CD1 3.24Å; A210-F212 WeakPolarHBondContact O-CD1 3.47Å; A210-F212 WeakPolarHBondContact O-CE1 3.41Å
211G97.3Very high95.1Very high70 Ų7064.6 Ų64.672%0.72234%0.342SS*.THydrogen-bonded Turntrans80.323.7-179.700000113.9E207E207-G211 PolarHBondContact O-N 3.25Å
212F97.2Very high94.6Very high27 Ų2766.3 Ų66.312%0.11835%0.352CS..SBendtrans-151.8159.1177.846-105.8000112.6P6 W27 F166 E207 A210 I214P6-F212 HydrophobicContact CB-CB 4.04Å; P6-F212 HydrophobicContact CB-CD2 3.52Å; P6-F212 HydrophobicContact CB-CE2 4.1Å; P6-F212 HydrophobicContact CB-CG 3.92Å; P6-F212 WeakPolarHBondContact O-CB 3.48Å; W27-F212 HydrophobicContact CB-CE2 4.36Å; W27-F212 HydrophobicContact CB-CZ 3.92Å; W27-F212 AromaticContact CD1-CE1 3.72Å; W27-F212 AromaticContact CD1-CZ 3.75Å; W27-F212 HydrophobicContact CG-CE2 4.49Å; W27-F212 HydrophobicContact CG-CZ 4.18Å; F166-F212 HydrophobicContact CE1-CE2 4.19Å; F166-F212 AromaticContact CE1-CZ 3.8Å; F166-F212 HydrophobicContact CE1-CZ 3.8Å; F166-F212 AromaticContact CZ-CE2 3.73Å; F166-F212 HydrophobicContact CZ-CE2 3.73Å; F166-F212 AromaticContact CZ-CZ 3.68Å; F166-F212 HydrophobicContact CZ-CZ 3.68Å; E207-F212 VanDerWaalsContact CA-O 3.23Å; E207-F212 WeakPolarHBondContact CA-O 3.35Å; E207-F212 VanDerWaalsContact CB-O 3.27Å; E207-F212 WeakPolarHBondContact CB-O 3.39Å; E207-F212 WeakPolarHBondContact CG-O 3.25Å; E207-F212 PolarHBondContact O-N 2.69Å; A210-F212 HydrophobicContact CB-CD1 4.01Å; A210-F212 HydrophobicContact CB-CD2 4.06Å; A210-F212 HydrophobicContact CB-CE1 3.57Å; A210-F212 HydrophobicContact CB-CE2 3.65Å; A210-F212 HydrophobicContact CB-CG 4.25Å; A210-F212 HydrophobicContact CB-CZ 3.4Å; A210-F212 VanDerWaalsContact CB-CZ 3.4Å; A210-F212 VanDerWaalsContact O-CD1 3.24Å; A210-F212 WeakPolarHBondContact O-CD1 3.47Å; A210-F212 WeakPolarHBondContact O-CE1 3.41Å; F212-I214 HydrophobicContact CD2-CD1 4.4Å; F212-I214 HydrophobicContact CD2-CG1 3.94Å; F212-I214 HydrophobicContact CE2-CD1 4.06Å; F212-I214 HydrophobicContact CE2-CG1 4.03Å
213L97.6Very high94.4Very high88 Ų8864.4 Ų64.446%0.46134%0.338SS..  trans-92.6140.7177.7-61.6177.4000111.2P6 E207 Q216P6-L213 WeakPolarHBondContact CA-O 3.49Å; P6-L213 WeakPolarHBondContact CB-O 3.46Å; E207-L213 HydrophobicContact CB-CD2 4.47Å; E207-L213 WeakPolarHBondContact OE1-CA 3.35Å; L213-Q216 HydrophobicContact CB-CB 4.12Å; L213-Q216 HydrophobicContact CD1-CB 4.45Å
214I97.9Very high94.3Very high3 Ų367.9 Ų67.92%0.01536%0.356CS..SBendtrans-115126.3-176.5-58.6171.8000108.8C132 F166 V168 L203 I206 E207 F212 Q216C132-I214 HydrophobicContact CB-CG2 3.81Å; F166-I214 HydrophobicContact CD2-CD1 4.43Å; F166-I214 HydrophobicContact CE2-CD1 3.9Å; F166-I214 HydrophobicContact CZ-CD1 4.38Å; V168-I214 HydrophobicContact CB-CG2 4.2Å; V168-I214 HydrophobicContact CG1-CG2 4.18Å; V168-I214 HydrophobicContact CG2-CD1 3.82Å; L203-I214 HydrophobicContact CD1-CB 4.12Å; L203-I214 HydrophobicContact CD1-CD1 4.33Å; L203-I214 HydrophobicContact CD1-CG2 4.48Å; I206-I214 HydrophobicContact CG2-CD1 3.9Å; E207-I214 HydrophobicContact CG-CB 4.5Å; E207-I214 HydrophobicContact CG-CG1 4.3Å; E207-I214 PolarHBondContact OE1-N 3.4Å; F212-I214 HydrophobicContact CD2-CD1 4.4Å; F212-I214 HydrophobicContact CD2-CG1 3.94Å; F212-I214 HydrophobicContact CE2-CD1 4.06Å; F212-I214 HydrophobicContact CE2-CG1 4.03Å; I214-Q216 VanDerWaalsContact C-N 3.27Å; I214-Q216 PolarHBondContact O-N 2.86Å
215F97.3Very high94.3Very high13 Ų1366.2 Ų66.26%0.05735%0.351CS..SBendtrans58.332.7-178-49.1-48000114.8F3 M29 Y130 C132 V168 L170 L180 N217 L218F3-F215 HydrophobicContact CB-CB 4.04Å; F3-F215 HydrophobicContact CB-CD1 3.92Å; F3-F215 HydrophobicContact CB-CG 4.41Å; F3-F215 CarbonylContact O-C 3.25Å; F3-F215 VanDerWaalsContact O-C 3.25Å; F3-F215 VanDerWaalsContact O-CA 3.28Å; F3-F215 WeakPolarHBondContact O-CA 3.41Å; M29-F215 HydrophobicContact CE-CE1 4.22Å; M29-F215 HydrophobicContact SD-CE1 3.66Å; M29-F215 HydrophobicContact SD-CZ 4.24Å; Y130-F215 WeakPolarHBondContact O-CZ 3.49Å; C132-F215 HydrophobicContact CB-CZ 4.25Å; V168-F215 HydrophobicContact CB-CE2 4.3Å; V168-F215 HydrophobicContact CG1-CD2 4.22Å; V168-F215 HydrophobicContact CG1-CE2 3.72Å; L170-F215 HydrophobicContact CB-CD2 3.64Å; L170-F215 HydrophobicContact CB-CE1 4.42Å; L170-F215 HydrophobicContact CB-CE2 3.41Å; L170-F215 VanDerWaalsContact CB-CE2 3.41Å; L170-F215 HydrophobicContact CB-CG 4.25Å; L170-F215 HydrophobicContact CB-CZ 3.85Å; L170-F215 HydrophobicContact CD2-CB 4.23Å; L170-F215 HydrophobicContact CD2-CD1 4.24Å; L170-F215 HydrophobicContact CD2-CD2 4.13Å; L170-F215 HydrophobicContact CD2-CG 3.94Å; L170-F215 HydrophobicContact CG-CD2 4.42Å; L180-F215 HydrophobicContact CD1-CD2 3.98Å; L180-F215 HydrophobicContact CD1-CE2 4.45Å; F215-N217 PolarHBondContact O-N 2.91Å; F215-L218 WeakPolarHBondContact O-CB 3.43Å; F215-L218 PolarHBondContact O-N 3.17Å
216Q95Very high94.2Very high100 Ų10065.9 Ų65.947%0.46734%0.344SS..THydrogen-bonded Turntrans-52.5-27.5-176.361.8176.9-18.700115.2F3 Y5 L213 I214 L218F3-Q216 PolarHBondContact O-N 3.02Å; Y5-Q216 PolarHBondContact O-NE2 3.12Å; L213-Q216 HydrophobicContact CB-CB 4.12Å; L213-Q216 HydrophobicContact CD1-CB 4.45Å; I214-Q216 VanDerWaalsContact C-N 3.27Å; I214-Q216 PolarHBondContact O-N 2.86Å; Q216-L218 VanDerWaalsContact C-N 3.33Å
217N95.4Very high94.2Very high105 Ų10566.9 Ų66.956%0.56135%0.349SS*.THydrogen-bonded Turntrans-85.4-2.5-179.2-65.1-10.2000113.4F3 F215 P219F3-N217 PolarHBondContact O-N 3.49Å; F215-N217 PolarHBondContact O-N 2.91Å; N217-P219 WeakPolarHBondContact O-CD 3.44Å
218L91.1Very high93.9Very high18 Ų1868.9 Ų68.99%0.09438%0.376CS..SBendtrans-85.3118.1171.7-175.177.7000109.3F3 L170 W178 F215 Q216 R220 C222 L223F3-L218 HydrophobicContact CD1-CB 3.95Å; F3-L218 HydrophobicContact CD1-CD1 4.05Å; F3-L218 HydrophobicContact CE1-CB 4.45Å; F3-L218 HydrophobicContact CE1-CD1 3.67Å; F3-L218 HydrophobicContact CG-CB 4.48Å; F3-L218 HydrophobicContact CZ-CD1 4.23Å; L170-L218 HydrophobicContact CD1-CD2 3.44Å; L170-L218 VanDerWaalsContact CD1-CD2 3.44Å; L170-L218 HydrophobicContact CD2-CD2 3.81Å; L170-L218 HydrophobicContact CG-CD2 4.26Å; W178-L218 HydrophobicContact CD2-CD1 4.29Å; W178-L218 HydrophobicContact CG-CD1 4.47Å; F215-L218 WeakPolarHBondContact O-CB 3.43Å; F215-L218 PolarHBondContact O-N 3.17Å; Q216-L218 VanDerWaalsContact C-N 3.33Å; L218-R220 PolarHBondContact O-N 3.31Å; L218-R220 VanDerWaalsContact O-N 3.17Å; L218-C222 HydrophobicContact CD1-CB 4.36Å; L218-L223 HydrophobicContact CD2-CD1 4.48Å; L218-L223 HydrophobicContact CD2-CD2 3.67Å; L218-L223 HydrophobicContact CD2-CG 3.96Å
219P84.2Confident93.5Very high66 Ų6671.3 Ų71.343%0.42939%0.385SS..  trans-60.1123.5173.5-20.932.9000109.9N217 K221 C222N217-P219 WeakPolarHBondContact O-CD 3.44Å; P219-K221 HydrophobicContact CB-CG 3.94Å; P219-K221 PolarHBondContact O-N 2.72Å; P219-C222 VanDerWaalsContact O-CB 3.26Å; P219-C222 WeakPolarHBondContact O-CB 3.27Å; P219-C222 PolarHBondContact O-N 2.93Å
220R81.9Confident93.3Very high145 Ų14572.7 Ų72.755%0.54739%0.386SS..G310 helixtrans-55.1-29.9-177.7-70.8-170.7172.3-146.5-5113.7E204 L218 C222 L223E204-R220 IonicContact OE1-CZ 2.61Å; E204-R220 IonicContact OE1-NH1 3.26Å; E204-R220 PolarHBondContact OE1-NH1 3.19Å; E204-R220 IonicContact OE1-NH2 3.86Å; E204-R220 PolarHBondContact OE1-NH2 3.32Å; L218-R220 PolarHBondContact O-N 3.31Å; L218-R220 VanDerWaalsContact O-N 3.17Å; R220-C222 PolarHBondContact O-N 2.84Å; R220-C222 VanDerWaalsContact O-N 3.14Å; R220-L223 WeakPolarHBondContact O-CB 3.48Å; R220-L223 PolarHBondContact O-N 3.44Å
221K84.6Confident93Very high190 Ų19075.2 Ų75.283%0.82640%0.395SS*.G310 helixtrans-60.4-17.617465.1177.2-179.8179.80114.7P219 L223P219-K221 HydrophobicContact CB-CG 3.94Å; P219-K221 PolarHBondContact O-N 2.72Å; K221-L223 VanDerWaalsContact C-N 3.32Å
222C87.9Confident92.8Very high49 Ų4975.4 Ų75.433%0.33138%0.377SS..G310 helixtrans-80.4-16.9175.8-63.40000112.3W178 L218 P219 R220W178-C222 WeakPolarHBondContact CB-O 3.45Å; L218-C222 HydrophobicContact CD1-CB 4.36Å; P219-C222 VanDerWaalsContact O-CB 3.26Å; P219-C222 WeakPolarHBondContact O-CB 3.27Å; P219-C222 PolarHBondContact O-N 2.93Å; R220-C222 PolarHBondContact O-N 2.84Å; R220-C222 VanDerWaalsContact O-N 3.14Å
223L93.3Very high92.5Very high31 Ų3178.3 Ų78.316%0.16239%0.392CS..EExtended strand (participates in β ladder)trans-77.7122.5177.5-65.2170.8000109.9L170 W178 L180 L218 R220 K221 I226L170-L223 HydrophobicContact CD1-CD2 3.7Å; W178-L223 HydrophobicContact CB-CD2 3.96Å; W178-L223 CarbonylContact O-C 3.56Å; W178-L223 VanDerWaalsContact O-CA 3.26Å; W178-L223 WeakPolarHBondContact O-CA 3.35Å; L180-L223 HydrophobicContact CB-CD2 4.1Å; L218-L223 HydrophobicContact CD2-CD1 4.48Å; L218-L223 HydrophobicContact CD2-CD2 3.67Å; L218-L223 HydrophobicContact CD2-CG 3.96Å; R220-L223 WeakPolarHBondContact O-CB 3.48Å; R220-L223 PolarHBondContact O-N 3.44Å; K221-L223 VanDerWaalsContact C-N 3.32Å; L223-I226 HydrophobicContact CD1-CD1 3.97Å; L223-I226 HydrophobicContact CD1-CG1 4.09Å
224I95.9Very high92.2Very high86 Ų8677.7 Ų77.744%0.44139%0.388SS..EExtended strand (participates in β ladder)trans-85.6-20.3173.565.4164.9000112.5R177 W178 F179R177-I224 HydrophobicContact CB-CD1 3.89Å; R177-I224 HydrophobicContact CB-CG1 4.37Å; R177-I224 HydrophobicContact CB-CG2 3.94Å; R177-I224 HydrophobicContact CG-CG2 4.28Å; W178-I224 VanDerWaalsContact O-CG1 3.26Å; W178-I224 WeakPolarHBondContact O-CG1 3.46Å; W178-I224 PolarHBondContact O-N 3.13Å; F179-I224 HydrophobicContact CB-CG1 4.33Å
225S96Very high91.9Very high28 Ų2882.7 Ų82.720%0.19641%0.413CS..EExtended strand (participates in β ladder)trans-161.2155.6172.864.60000112.6F179 L180 R229F179-S225 WeakPolarHBondContact CA-O 3.4Å; F179-S225 VanDerWaalsContact CB-OG 3.27Å; F179-S225 WeakPolarHBondContact CB-OG 3.44Å; L180-S225 PolarHBondContact N-O 3.11Å; S225-R229 CarbonylContact C-O 3.58Å; S225-R229 WeakPolarHBondContact CA-O 3.42Å; S225-R229 WeakPolarHBondContact CB-O 3.5Å
226I96.4Very high91.5Very high57 Ų5787.6 Ų87.629%0.29244%0.438SS..EExtended strand (participates in β ladder)trans-127.9121.8171.1-58179.2000108L180 L223 G228 R229L180-I226 HydrophobicContact CD2-CG2 3.97Å; L180-I226 CarbonylContact O-C 3.49Å; L180-I226 WeakPolarHBondContact O-CA 3.47Å; L223-I226 HydrophobicContact CD1-CD1 3.97Å; L223-I226 HydrophobicContact CD1-CG1 4.09Å; I226-G228 PolarHBondContact O-N 3.41Å; I226-R229 PolarHBondContact N-O 2.97Å; I226-R229 PolarHBondContact O-N 2.73Å
227N97.2Very high91.2Very high22 Ų2286.7 Ų86.712%0.11844%0.436CS..THydrogen-bonded Turntrans55.133-176.4-63.5-29.6000113.2L180 E181 S182 Y200 A201 R229L180-N227 PolarHBondContact O-N 2.89Å; E181-N227 WeakPolarHBondContact CA-OD1 3.43Å; S182-N227 PolarHBondContact N-OD1 3.36Å; S182-N227 PolarHBondContact OG-ND2 2.87Å; S182-N227 VanDerWaalsContact OG-ND2 3.15Å; S182-N227 PolarHBondContact OG-OD1 3.19Å; Y200-N227 HydrophobicContact CD1-CB 4Å; Y200-N227 WeakPolarHBondContact CD1-OD1 3.4Å; Y200-N227 HydrophobicContact CD2-CB 3.74Å; Y200-N227 HydrophobicContact CE1-CB 4.26Å; Y200-N227 HydrophobicContact CE2-CB 4Å; Y200-N227 WeakPolarHBondContact CE2-O 3.22Å; Y200-N227 HydrophobicContact CG-CB 3.75Å; A201-N227 PolarHBondContact O-ND2 3.3Å; N227-R229 VanDerWaalsContact C-N 3.29Å; N227-R229 PolarHBondContact O-N 3.12Å
228G93.1Very high90.8Very high65 Ų6585.2 Ų85.267%0.6743%0.426SS*.THydrogen-bonded Turntrans73.913.9-178.500000115I226I226-G228 PolarHBondContact O-N 3.41Å
229R88.7Confident90.8Very high265 Ų26591.3 Ų91.3100%146%0.456SS*.  trans-110.30172.2-59.9-175.1-174.2-171.91.2111.3S225 I226 N227S225-R229 CarbonylContact C-O 3.58Å; S225-R229 WeakPolarHBondContact CA-O 3.42Å; S225-R229 WeakPolarHBondContact CB-O 3.5Å; I226-R229 PolarHBondContact N-O 2.97Å; I226-R229 PolarHBondContact O-N 2.73Å; N227-R229 VanDerWaalsContact C-N 3.29Å; N227-R229 PolarHBondContact O-N 3.12Å

Retrieved 229 of 229 residues in 91.4 ms (Link to these results)