A0A077YX57_TRITR Loading...

Enolase

AlphaFold DB , UniProt , Accession A0A077YX57, Species TRITR (Trichuris trichiura, Whipworm), Gene n/a, Length 454 aa.

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Site Residue pLDDT pLDDT confidence pLDDT10 pLDDT10 confidence SASA SASA [Ų] SASA10 SASA10 [Ų] RSA RSA unformatted RSA10 RSA10 unformatted Surface Surface10 (not used) Disorder (not used) Disorder Sec. str. Secondary structure Isomer Phi (φ) Psi (ψ) Omega (ω) Chi 1 (χ1) Chi 2 (χ2) Chi 3 (χ3) Chi 4 (χ4) Chi 5 (χ5) Tau (τ) Contacts (colored by PAE) Contact details
1M40.8Very low41.9Very low248 Ų248142.9 Ų142.9100%1.22283%0.83SS**  0930-76.6-174.3-80.300108.5
2C41.1Very low42.8Very low132 Ų132138.9 Ų138.989%0.89281%0.808SS**  trans-100.893.1173.3-165.60000106.9C4C2-C4 PolarHBondContact O-N 3.33Å
3G41.7Very low44.3Very low66 Ų66134.3 Ų134.368%0.6880%0.796SS**  trans-77.4107.6-179.800000110.3V5G3-V5 PolarHBondContact O-N 3.03Å
4C40.8Very low46.6Very low130 Ų130136.4 Ų136.488%0.87879%0.794SS**  trans-64.1100.2163.5-81.50000108.8C2 G6C2-C4 PolarHBondContact O-N 3.33Å; C4-G6 VanDerWaalsContact C-N 3.28Å; C4-G6 PolarHBondContact O-N 3.01Å
5V40.9Very low49Very low135 Ų135127.5 Ų127.582%0.81874%0.742SS**  trans-74.490165.3-175.10000106.8G3 R7G3-V5 PolarHBondContact O-N 3.03Å; V5-R7 PolarHBondContact O-N 3.03Å
6G40.5Very low51.5Low62 Ų62122.7 Ų122.764%0.63972%0.718SS**  trans-60116.6167.900000108.6C4 L8C4-G6 VanDerWaalsContact C-N 3.28Å; C4-G6 PolarHBondContact O-N 3.01Å; G6-L8 PolarHBondContact O-N 3.2Å
7R40.4Very low54Low241 Ų241116.1 Ų116.191%0.90968%0.679SS**  trans-62.4108.6165.3-70.7-177.6-166-137.51.8106.6V5 S9V5-R7 PolarHBondContact O-N 3.03Å; R7-S9 PolarHBondContact O-N 2.82Å
8L40.5Very low56.2Low175 Ų175114.6 Ų114.692%0.91667%0.666SS**  trans-61.588.7160.6-79.7155.1000106.8G6 S10G6-L8 PolarHBondContact O-N 3.2Å; L8-S10 PolarHBondContact O-N 2.89Å; L8-S10 VanDerWaalsContact O-N 3.08Å
9S41.8Very low58.3Low91 Ų91113.8 Ų113.864%0.63666%0.655SS**  trans-58.2110.1156173.50000105.2R7 F11R7-S9 PolarHBondContact O-N 2.82Å; S9-F11 VanDerWaalsContact C-N 3.32Å; S9-F11 PolarHBondContact O-N 3.08Å
10S44.8Very low60.3Low97 Ų97108.8 Ų108.868%0.67863%0.626SS**  trans-60101.4168.754.70000106.7L8 V12L8-S10 PolarHBondContact O-N 2.89Å; L8-S10 VanDerWaalsContact O-N 3.08Å; S10-V12 PolarHBondContact O-N 3.06Å
11F47.4Very low62.1Low195 Ų195107.1 Ų107.186%0.85561%0.612SS**  trans-60.190.8160.3-89.4-93.1000106.2S9 A13S9-F11 VanDerWaalsContact C-N 3.32Å; S9-F11 PolarHBondContact O-N 3.08Å; F11-A13 VanDerWaalsContact C-N 3.34Å; F11-A13 PolarHBondContact O-N 2.82Å
12V53.3Low64.9Low95 Ų9595.4 Ų95.458%0.57656%0.555SS**  trans-66.5106.7160.8-176.20000103.6S10 E14S10-V12 PolarHBondContact O-N 3.06Å; V12-E14 PolarHBondContact O-N 3.2Å
13A61.7Low67.6Low79 Ų7992.7 Ų92.765%0.65353%0.526SS*.  trans-55.7125.6179.600000109F11 M15 H139F11-A13 VanDerWaalsContact C-N 3.34Å; F11-A13 PolarHBondContact O-N 2.82Å; A13-M15 PolarHBondContact O-N 3.35Å; A13-H139 PolarHBondContact O-CE1 2.66Å
14E76.9Confident70.3Confident163 Ų16391.9 Ų91.976%0.76250%0.504SS*.  trans-49126.4170.9-81.3178.4-172.800109.7V12 E97V12-E14 PolarHBondContact O-N 3.2Å; E14-E97 VanDerWaalsContact C-OE2 3.31Å; E14-E97 VanDerWaalsContact CA-OE2 3.23Å; E14-E97 WeakPolarHBondContact CA-OE2 3.31Å; E14-E97 VanDerWaalsContact CB-OE1 3.31Å; E14-E97 WeakPolarHBondContact CB-OE1 3.23Å; E14-E97 HydrophobicContact CG-CG 4.32Å
15M83Confident73.1Confident3 Ų387.5 Ų87.52%0.01547%0.472CS..  trans-111.488.6177.3-167170.787.300110.1A13 T40 R42 F45 E97 V98 A135 H139A13-M15 PolarHBondContact O-N 3.35Å; M15-T40 HydrophobicContact CE-CG2 3.86Å; M15-T40 VanDerWaalsContact CG-CB 3.44Å; M15-T40 HydrophobicContact CG-CG2 3.89Å; M15-T40 WeakPolarHBondContact CG-OG1 3.47Å; M15-T40 HydrophobicContact SD-CG2 4.17Å; M15-T40 PolarHBondContact SD-OG1 2.99Å; M15-R42 HydrophobicContact SD-CB 3.74Å; M15-R42 HydrophobicContact SD-CG 3.57Å; M15-R42 VanDerWaalsContact SD-CG 3.57Å; M15-F45 HydrophobicContact CE-CE2 4.3Å; M15-F45 HydrophobicContact CE-CZ 4.37Å; M15-E97 PolarHBondContact N-OE1 3.34Å; M15-E97 PolarHBondContact N-OE2 3.35Å; M15-V98 HydrophobicContact CB-CG2 4.49Å; M15-V98 HydrophobicContact CE-CG2 3.37Å; M15-V98 PolarHBondContact O-N 3.35Å; M15-A135 HydrophobicContact CE-CB 4.23Å; M15-A135 WeakPolarHBondContact CE-O 3.48Å; M15-H139 WeakPolarHBondContact CB-ND1 3.17Å; M15-H139 HydrophobicContact CE-CB 3.58Å; M15-H139 HydrophobicContact SD-CB 4.34Å
16S88.6Confident75.8Confident51 Ų5187.4 Ų87.436%0.35746%0.458SS..BIsolated β-bridgetrans-74.1159.317366.70000112.9M18 E97S16-M18 PolarHBondContact O-N 3.38Å; S16-E97 PolarHBondContact N-OE1 3.24Å
17I93.6Very high78.6Confident10 Ų1084.9 Ų84.95%0.05143%0.43CS..  trans-69.9110.5167.6-58.2172.4000109.6L20 L38 L91 V98 I104 V132I17-L20 HydrophobicContact CG2-CD1 3.87Å; I17-L20 HydrophobicContact CG2-CG 3.73Å; I17-L38 HydrophobicContact CD1-CD1 4.36Å; I17-L38 HydrophobicContact CG1-CD1 4.22Å; I17-L38 HydrophobicContact CG1-CD2 4.49Å; I17-L38 HydrophobicContact CG1-CG 4.5Å; I17-L38 HydrophobicContact CG2-CG 4.27Å; I17-L91 HydrophobicContact CD1-CB 4.31Å; I17-L91 HydrophobicContact CD1-CD1 4.22Å; I17-V98 HydrophobicContact CG1-CG1 3.74Å; I17-I104 HydrophobicContact CD1-CD1 4.26Å; I17-V132 HydrophobicContact CD1-CG2 4.31Å
18M93.9Very high81.3Confident90 Ų9075 Ų7544%0.44340%0.398SS..  trans-82.9-40.8179.8-64.8178.16700112.4S16 K39 S41 K92S16-M18 PolarHBondContact O-N 3.38Å; M18-K39 WeakPolarHBondContact CB-O 3.37Å; M18-K39 PolarHBondContact N-O 3.15Å; M18-S41 PolarHBondContact SD-N 2.91Å; M18-S41 VanDerWaalsContact SD-N 3.38Å; M18-K92 PolarHBondContact O-NZ 3.48Å
19E96.2Very high83.9Confident99 Ų9969.7 Ų69.746%0.46337%0.365SS..EExtended strand (participates in β ladder)trans-152.4144.1-176.5-169.2-179167.200109.4K39E19-K39 HydrophobicContact CB-CB 3.94Å; E19-K39 HydrophobicContact CB-CD 4.28Å; E19-K39 PolarHBondContact N-O 3.25Å; E19-K39 PolarHBondContact O-N 3.32Å; E19-K39 IonicContact OE2-NZ 2.69Å
20L97.9Very high86.5Confident14 Ų1467.6 Ų67.67%0.07336%0.358CS..EExtended strand (participates in β ladder)trans-127.8128.5169.3-84.8165.9000106.9I17 V36 D37 L38 A88 L91 V128I17-L20 HydrophobicContact CG2-CD1 3.87Å; I17-L20 HydrophobicContact CG2-CG 3.73Å; L20-V36 HydrophobicContact CD2-CG1 3.81Å; L20-D37 WeakPolarHBondContact CA-O 3.11Å; L20-L38 HydrophobicContact CD2-CB 3.7Å; L20-L38 HydrophobicContact CD2-CD1 4.05Å; L20-L38 HydrophobicContact CD2-CG 3.78Å; L20-L38 HydrophobicContact CG-CG 4.46Å; L20-A88 HydrophobicContact CB-CB 3.58Å; L20-A88 HydrophobicContact CD1-CB 4.33Å; L20-L91 HydrophobicContact CD1-CB 4.4Å; L20-L91 HydrophobicContact CD1-CD1 3.68Å; L20-V128 HydrophobicContact CD1-CG1 4.09Å; L20-V128 HydrophobicContact CD2-CG1 4.26Å
21H98.5Very high89Confident74 Ų7465.1 Ų65.134%0.34334%0.337SS..EExtended strand (participates in β ladder)trans-135.5121.3177.7173.585.7000109.5R23 D37H21-R23 PolarHBondContact CD2-NH2 3.19Å; H21-R23 PolarHBondContact NE2-NE 3.16Å; H21-D37 PolarHBondContact N-O 2.94Å; H21-D37 PolarHBondContact O-N 3.42Å
22A98.8Very high91.5Very high2 Ų255.9 Ų55.92%0.01730%0.297CS..EExtended strand (participates in β ladder)trans-104.3149.417400000111.6E35 V36 V80 I83 N84A22-E35 CarbonylContact C-O 3.44Å; A22-E35 WeakPolarHBondContact CA-O 3.43Å; A22-V36 HydrophobicContact CB-CG2 4.18Å; A22-V80 HydrophobicContact CB-CG1 4.12Å; A22-V80 WeakPolarHBondContact O-CG1 3.39Å; A22-I83 HydrophobicContact CB-CB 3.62Å; A22-I83 HydrophobicContact CB-CD1 3.6Å; A22-I83 HydrophobicContact CB-CG1 4.22Å; A22-I83 HydrophobicContact CB-CG2 3.6Å; A22-N84 PolarHBondContact N-OD1 2.91Å; A22-N84 PolarHBondContact O-ND2 3.15Å
23R98.8Very high93.6Very high75 Ų7551.3 Ų51.328%0.28327%0.27SS..EExtended strand (participates in β ladder)trans-143.4163.617565.6-174.569.1116.1-0.4111.5H21 I25 E35 D37 R46H21-R23 PolarHBondContact CD2-NH2 3.19Å; H21-R23 PolarHBondContact NE2-NE 3.16Å; R23-I25 HydrophobicContact CG-CG2 4.12Å; R23-E35 WeakPolarHBondContact CD-OE2 3.48Å; R23-E35 HydrophobicContact CG-CB 4.04Å; R23-E35 IonicContact CZ-OE2 3.84Å; R23-E35 PolarHBondContact N-O 3.43Å; R23-E35 IonicContact NE-OE2 2.78Å; R23-E35 IonicContact NH1-OE2 3.26Å; R23-E35 PolarHBondContact NH1-OE2 3.11Å; R23-E35 PolarHBondContact O-N 3.21Å; R23-D37 IonicContact CZ-OD2 3.83Å; R23-D37 VanDerWaalsContact CZ-OD2 3.22Å; R23-D37 IonicContact NH1-OD2 3.27Å; R23-D37 PolarHBondContact NH1-OD2 3.08Å; R23-D37 IonicContact NH2-OD2 2.78Å; R23-D37 PolarHBondContact NH2-OD2 3.25Å; R23-R46 VanDerWaalsContact NH1-CZ 3.26Å
24Q98.7Very high95.4Very high48 Ų4847.6 Ų47.622%0.22424%0.238CC..EExtended strand (participates in β ladder)trans-87.7127170.3-179.2172-80.600109.6P32 T33 H71 V76 L77Q24-P32 HydrophobicContact CG-CB 3.76Å; Q24-T33 CarbonylContact C-O 3.54Å; Q24-T33 WeakPolarHBondContact CA-O 3.36Å; Q24-H71 PolarHBondContact NE2-NE2 3.29Å; Q24-V76 HydrophobicContact CB-CG2 4.07Å; Q24-V76 HydrophobicContact CG-CG2 3.72Å; Q24-L77 HydrophobicContact CB-CD2 4.09Å
25I98.6Very high96.4Very high38 Ų3841 Ų4120%0.19521%0.207CC..EExtended strand (participates in β ladder)trans-122.9-164.9169.364.6158.8000109.2R23 P32 T33 E35 A48R23-I25 HydrophobicContact CG-CG2 4.12Å; I25-P32 CarbonylContact O-C 3.5Å; I25-P32 WeakPolarHBondContact O-CA 3.46Å; I25-T33 HydrophobicContact CD1-CG2 4.11Å; I25-T33 HydrophobicContact CG1-CG2 3.71Å; I25-T33 PolarHBondContact N-O 2.65Å; I25-T33 PolarHBondContact O-N 3.39Å; I25-E35 HydrophobicContact CD1-CB 3.97Å; I25-E35 HydrophobicContact CG1-CB 3.98Å; I25-E35 HydrophobicContact CG2-CB 3.81Å; I25-A48 HydrophobicContact CD1-CB 3.85Å
26Y98.3Very high97.2Very high134 Ų13440.8 Ų40.853%0.52521%0.207SC..EExtended strand (participates in β ladder)trans-120.1146176.9-64.3-87.3000112G30 N31 P32 H71Y26-G30 WeakPolarHBondContact CD1-O 3.38Å; Y26-N31 CarbonylContact C-O 3.53Å; Y26-N31 VanDerWaalsContact CA-O 3.31Å; Y26-N31 WeakPolarHBondContact CA-O 3.35Å; Y26-P32 HydrophobicContact CE1-CG 4.31Å; Y26-H71 PolarHBondContact OH-CE1 3.17Å
27D98Very high97.7Very high9 Ų939 Ų395%0.04819%0.193CC..  trans-86.1176.316976.98.2000111.6R29 G30 N31 T33 G393 E394D27-R29 PolarHBondContact O-N 3.33Å; D27-R29 WeakPolarHBondContact OD1-CA 3.43Å; D27-R29 WeakPolarHBondContact OD1-CB 3.47Å; D27-R29 PolarHBondContact OD1-N 3.3Å; D27-R29 IonicContact OD2-CZ 3.38Å; D27-R29 IonicContact OD2-NE 3.53Å; D27-R29 PolarHBondContact OD2-NE 2.9Å; D27-R29 IonicContact OD2-NH2 3.58Å; D27-R29 PolarHBondContact OD2-NH2 3.03Å; D27-G30 PolarHBondContact O-N 3.04Å; D27-G30 PolarHBondContact OD1-N 3.35Å; D27-N31 PolarHBondContact N-O 3.28Å; D27-N31 PolarHBondContact OD1-N 3.33Å; D27-T33 HydrophobicContact CB-CG2 4.22Å; D27-G393 VanDerWaalsContact OD2-CA 3.31Å; D27-G393 WeakPolarHBondContact OD2-CA 3.43Å; D27-E394 CarbonylContact C-O 3.53Å; D27-E394 WeakPolarHBondContact CA-O 2.98Å
28S97.4Very high97.9Very high34 Ų3438.6 Ų38.624%0.23819%0.191CC..THydrogen-bonded Turntrans-61.3-13.5-179.161.80000114.9S392 E394 E421S28-S392 PolarHBondContact OG-O 3.46Å; S28-E394 WeakPolarHBondContact CB-O 3.47Å; S28-E394 PolarHBondContact N-O 3.05Å; S28-E394 PolarHBondContact OG-N 3.12Å; S28-E421 WeakPolarHBondContact CA-OE1 3.21Å; S28-E421 WeakPolarHBondContact CB-OE1 3.27Å
29R95.9Very high98.1Very high62 Ų6238.4 Ų38.423%0.23419%0.188CC..THydrogen-bonded Turntrans-98.83.5176.1-58.6171.7-59.6174.6-3.2111.7D27 N31 S51 G52 A53 D223D27-R29 PolarHBondContact O-N 3.33Å; D27-R29 WeakPolarHBondContact OD1-CA 3.43Å; D27-R29 WeakPolarHBondContact OD1-CB 3.47Å; D27-R29 PolarHBondContact OD1-N 3.3Å; D27-R29 IonicContact OD2-CZ 3.38Å; D27-R29 IonicContact OD2-NE 3.53Å; D27-R29 PolarHBondContact OD2-NE 2.9Å; D27-R29 IonicContact OD2-NH2 3.58Å; D27-R29 PolarHBondContact OD2-NH2 3.03Å; R29-N31 VanDerWaalsContact C-N 3.25Å; R29-N31 PolarHBondContact O-N 2.86Å; R29-S51 PolarHBondContact NH2-OG 2.99Å; R29-G52 VanDerWaalsContact NH1-C 3.32Å; R29-G52 PolarHBondContact NH1-O 2.8Å; R29-G52 PolarHBondContact NH2-O 3.36Å; R29-A53 VanDerWaalsContact NH1-CA 3.28Å; R29-D223 WeakPolarHBondContact CD-OD2 3.34Å
30G96.6Very high98.1Very high48 Ų4834 Ų3450%0.49517%0.167SC..SBendtrans7316.2-174.900000113.6Y26 D27Y26-G30 WeakPolarHBondContact CD1-O 3.38Å; D27-G30 PolarHBondContact O-N 3.04Å; D27-G30 PolarHBondContact OD1-N 3.35Å
31N97.8Very high98Very high44 Ų4437.8 Ų37.824%0.23520%0.195CC..  trans-88.4146.4173.3-67.5-58.5000110.1Y26 D27 R29Y26-N31 CarbonylContact C-O 3.53Å; Y26-N31 VanDerWaalsContact CA-O 3.31Å; Y26-N31 WeakPolarHBondContact CA-O 3.35Å; D27-N31 PolarHBondContact N-O 3.28Å; D27-N31 PolarHBondContact OD1-N 3.33Å; R29-N31 VanDerWaalsContact C-N 3.25Å; R29-N31 PolarHBondContact O-N 2.86Å
32P98.4Very high97.9Very high1 Ų140 Ų401%0.00620%0.2CC..EExtended strand (participates in β ladder)trans-56.4145.6173.8-26.935.6000113.1Q24 I25 Y26 R64 H71 V76Q24-P32 HydrophobicContact CG-CB 3.76Å; I25-P32 CarbonylContact O-C 3.5Å; I25-P32 WeakPolarHBondContact O-CA 3.46Å; Y26-P32 HydrophobicContact CE1-CG 4.31Å; P32-R64 PolarHBondContact O-NH1 3.45Å; P32-H71 HydrophobicContact CG-CB 3.69Å; P32-H71 VanDerWaalsContact CG-CG 3.4Å; P32-H71 WeakPolarHBondContact CG-ND1 3.36Å; P32-V76 HydrophobicContact CB-CG2 4.3Å
33T98.6Very high97.7Very high0 Ų041.4 Ų41.40%022%0.215CC..EExtended strand (participates in β ladder)trans-149.3175169.4-164.80000111.5Q24 I25 D27 V49 V76 T395Q24-T33 CarbonylContact C-O 3.54Å; Q24-T33 WeakPolarHBondContact CA-O 3.36Å; I25-T33 HydrophobicContact CD1-CG2 4.11Å; I25-T33 HydrophobicContact CG1-CG2 3.71Å; I25-T33 PolarHBondContact N-O 2.65Å; I25-T33 PolarHBondContact O-N 3.39Å; D27-T33 HydrophobicContact CB-CG2 4.22Å; T33-V49 WeakPolarHBondContact CG2-O 3.38Å; T33-V49 PolarHBondContact OG1-O 2.68Å; T33-V76 WeakPolarHBondContact O-CG2 3.38Å; T33-T395 HydrophobicContact CG2-CG2 3.95Å
34V98.8Very high97.7Very high0 Ų042.9 Ų42.90%023%0.228CC..EExtended strand (participates in β ladder)trans-93.8133.9-174.3178.30000110.8V36 A48 V49 V76 A79 V80 I83 N123V34-V36 HydrophobicContact CG1-CG2 3.99Å; V34-A48 WeakPolarHBondContact O-CA 3.43Å; V34-V49 HydrophobicContact CB-CB 4.49Å; V34-V49 HydrophobicContact CB-CG2 4.46Å; V34-V49 PolarHBondContact O-N 3.35Å; V34-V76 HydrophobicContact CG2-CB 3.98Å; V34-V76 HydrophobicContact CG2-CG2 3.94Å; V34-A79 HydrophobicContact CG2-CB 3.98Å; V34-V80 HydrophobicContact CG2-CG2 4.33Å; V34-I83 HydrophobicContact CG1-CD1 3.55Å; V34-N123 HydrophobicContact CG2-CB 4.4Å
35E98.8Very high97.7Very high24 Ų2441.6 Ų41.611%0.11222%0.221CC..EExtended strand (participates in β ladder)trans-120.6139.4164-179-177.8-95.700109.3A22 R23 I25 R46 A47 A48A22-E35 CarbonylContact C-O 3.44Å; A22-E35 WeakPolarHBondContact CA-O 3.43Å; R23-E35 WeakPolarHBondContact CD-OE2 3.48Å; R23-E35 HydrophobicContact CG-CB 4.04Å; R23-E35 IonicContact CZ-OE2 3.84Å; R23-E35 PolarHBondContact N-O 3.43Å; R23-E35 IonicContact NE-OE2 2.78Å; R23-E35 IonicContact NH1-OE2 3.26Å; R23-E35 PolarHBondContact NH1-OE2 3.11Å; R23-E35 PolarHBondContact O-N 3.21Å; I25-E35 HydrophobicContact CD1-CB 3.97Å; I25-E35 HydrophobicContact CG1-CB 3.98Å; I25-E35 HydrophobicContact CG2-CB 3.81Å; E35-R46 HydrophobicContact CG-CG 3.74Å; E35-R46 VanDerWaalsContact OE1-CD 3.26Å; E35-R46 WeakPolarHBondContact OE1-CD 3.22Å; E35-R46 IonicContact OE1-NE 3.22Å; E35-R46 IonicContact OE2-CZ 3.32Å; E35-R46 IonicContact OE2-NE 2.9Å; E35-R46 PolarHBondContact OE2-NE 3.46Å; E35-R46 IonicContact OE2-NH1 3.56Å; E35-A47 CarbonylContact C-O 3.52Å; E35-A47 WeakPolarHBondContact CA-O 3.39Å; E35-A48 HydrophobicContact CB-CB 4.47Å
36V98.9Very high97.7Very high0 Ų045.3 Ų45.30%023%0.233CC..EExtended strand (participates in β ladder)trans-123.6127.2178.7-178.60000109.9L20 A22 V34 R46 A47 I83 V128 A131L20-V36 HydrophobicContact CD2-CG1 3.81Å; A22-V36 HydrophobicContact CB-CG2 4.18Å; V34-V36 HydrophobicContact CG1-CG2 3.99Å; V36-R46 CarbonylContact O-C 3.57Å; V36-R46 VanDerWaalsContact O-CA 3.3Å; V36-R46 WeakPolarHBondContact O-CA 3.44Å; V36-A47 PolarHBondContact N-O 3.48Å; V36-A47 PolarHBondContact O-N 2.93Å; V36-I83 HydrophobicContact CG2-CD1 3.68Å; V36-V128 HydrophobicContact CG1-CG2 4.16Å; V36-V128 HydrophobicContact CG2-CG2 4.38Å; V36-A131 HydrophobicContact CG1-CB 4.28Å
37D98.8Very high97.7Very high14 Ų1439 Ų398%0.07521%0.208CC..EExtended strand (participates in β ladder)trans-98.3121.1164.5-80.5-26.4000109.5L20 H21 R23 I44 R46L20-D37 WeakPolarHBondContact CA-O 3.11Å; H21-D37 PolarHBondContact N-O 2.94Å; H21-D37 PolarHBondContact O-N 3.42Å; R23-D37 IonicContact CZ-OD2 3.83Å; R23-D37 VanDerWaalsContact CZ-OD2 3.22Å; R23-D37 IonicContact NH1-OD2 3.27Å; R23-D37 PolarHBondContact NH1-OD2 3.08Å; R23-D37 IonicContact NH2-OD2 2.78Å; R23-D37 PolarHBondContact NH2-OD2 3.25Å; D37-I44 HydrophobicContact CB-CG2 3.77Å; D37-I44 WeakPolarHBondContact OD1-CG2 3.43Å; D37-R46 WeakPolarHBondContact OD1-CB 3.43Å; D37-R46 IonicContact OD1-CZ 2.93Å; D37-R46 IonicContact OD1-NE 2.74Å; D37-R46 PolarHBondContact OD1-NE 3.28Å; D37-R46 IonicContact OD1-NH2 3.42Å; D37-R46 PolarHBondContact OD1-NH2 3.04Å; D37-R46 IonicContact OD2-CZ 2.89Å; D37-R46 IonicContact OD2-NE 3.25Å; D37-R46 IonicContact OD2-NH2 2.79Å; D37-R46 PolarHBondContact OD2-NH2 3.49Å
38L98.6Very high97.8Very high0 Ų038.9 Ų38.90%021%0.209CC..EExtended strand (participates in β ladder)trans-104.4121.2168.7-172.7164.5000108.8I17 L20 T40 I44 F45 V98 A131 V132 A135I17-L38 HydrophobicContact CD1-CD1 4.36Å; I17-L38 HydrophobicContact CG1-CD1 4.22Å; I17-L38 HydrophobicContact CG1-CD2 4.49Å; I17-L38 HydrophobicContact CG1-CG 4.5Å; I17-L38 HydrophobicContact CG2-CG 4.27Å; L20-L38 HydrophobicContact CD2-CB 3.7Å; L20-L38 HydrophobicContact CD2-CD1 4.05Å; L20-L38 HydrophobicContact CD2-CG 3.78Å; L20-L38 HydrophobicContact CG-CG 4.46Å; L38-T40 HydrophobicContact CD2-CG2 3.36Å; L38-I44 CarbonylContact O-C 3.57Å; L38-I44 WeakPolarHBondContact O-CA 3.46Å; L38-F45 HydrophobicContact CB-CB 4.49Å; L38-F45 HydrophobicContact CD2-CD2 4.11Å; L38-F45 PolarHBondContact N-O 3.31Å; L38-F45 WeakPolarHBondContact O-CD2 3.31Å; L38-F45 PolarHBondContact O-N 2.92Å; L38-V98 HydrophobicContact CD2-CG1 4.16Å; L38-A131 HydrophobicContact CB-CB 3.77Å; L38-A131 HydrophobicContact CD1-CB 4.34Å; L38-V132 HydrophobicContact CD1-CB 4.17Å; L38-V132 HydrophobicContact CD1-CG2 3.46Å; L38-V132 VanDerWaalsContact CD1-CG2 3.46Å; L38-A135 HydrophobicContact CD1-CB 4.47Å; L38-A135 HydrophobicContact CD2-CB 3.91Å
39K97.9Very high97.8Very high86 Ų8637.2 Ų37.237%0.37420%0.197SC..EExtended strand (participates in β ladder)trans-102.3135178.4-172177.2175.4179.70111.4M18 E19 G43 I44M18-K39 WeakPolarHBondContact CB-O 3.37Å; M18-K39 PolarHBondContact N-O 3.15Å; E19-K39 HydrophobicContact CB-CB 3.94Å; E19-K39 HydrophobicContact CB-CD 4.28Å; E19-K39 PolarHBondContact N-O 3.25Å; E19-K39 PolarHBondContact O-N 3.32Å; E19-K39 IonicContact OE2-NZ 2.69Å; K39-G43 WeakPolarHBondContact CA-O 3.49Å; K39-I44 HydrophobicContact CB-CG1 4.42Å; K39-I44 HydrophobicContact CG-CG1 4.21Å
40T96.2Very high97.9Very high6 Ų634.7 Ų34.74%0.03719%0.189CC..EExtended strand (participates in β ladder)trans-131.2-177.1168.680.50000110.6M15 L38 R42 G43 F45 V98 A135M15-T40 HydrophobicContact CE-CG2 3.86Å; M15-T40 VanDerWaalsContact CG-CB 3.44Å; M15-T40 HydrophobicContact CG-CG2 3.89Å; M15-T40 WeakPolarHBondContact CG-OG1 3.47Å; M15-T40 HydrophobicContact SD-CG2 4.17Å; M15-T40 PolarHBondContact SD-OG1 2.99Å; L38-T40 HydrophobicContact CD2-CG2 3.36Å; T40-R42 PolarHBondContact O-N 3.18Å; T40-R42 VanDerWaalsContact O-N 3.15Å; T40-R42 PolarHBondContact OG1-N 2.99Å; T40-R42 VanDerWaalsContact OG1-N 3.08Å; T40-G43 PolarHBondContact N-O 3.36Å; T40-G43 PolarHBondContact O-N 3.19Å; T40-F45 HydrophobicContact CG2-CD2 4.22Å; T40-F45 HydrophobicContact CG2-CE2 3.85Å; T40-F45 WeakPolarHBondContact OG1-CE2 3.32Å; T40-V98 HydrophobicContact CG2-CG1 4.01Å; T40-A135 HydrophobicContact CG2-CB 4.41Å
41S95.4Very high97.9Very high94 Ų9432.5 Ų32.566%0.65717%0.166SC*.THydrogen-bonded Turntrans-60.9-16.4172.555.80000113.9M18M18-S41 PolarHBondContact SD-N 2.91Å; M18-S41 VanDerWaalsContact SD-N 3.38Å
42R95.3Very high97.6Very high120 Ų12030.8 Ų30.845%0.45316%0.159SC..THydrogen-bonded Turntrans-102.9-1.6-178.4-65.9-169.565.7178.3-7.9114.7M15 T40 F45 V138 H139 N141M15-R42 HydrophobicContact SD-CB 3.74Å; M15-R42 HydrophobicContact SD-CG 3.57Å; M15-R42 VanDerWaalsContact SD-CG 3.57Å; T40-R42 PolarHBondContact O-N 3.18Å; T40-R42 VanDerWaalsContact O-N 3.15Å; T40-R42 PolarHBondContact OG1-N 2.99Å; T40-R42 VanDerWaalsContact OG1-N 3.08Å; R42-F45 HydrophobicContact CB-CZ 4.43Å; R42-V138 HydrophobicContact CB-CG1 4.34Å; R42-V138 PolarHBondContact NH1-O 3.02Å; R42-V138 PolarHBondContact NH2-O 3.24Å; R42-H139 PolarHBondContact NH1-O 3.45Å; R42-N141 PolarHBondContact NH2-OD1 3.04Å
43G96.7Very high97.1Very high32 Ų3232.9 Ų32.933%0.3318%0.176SC..EExtended strand (participates in β ladder)trans137.4-160.2176.700000113.5K39 T40K39-G43 WeakPolarHBondContact CA-O 3.49Å; T40-G43 PolarHBondContact N-O 3.36Å; T40-G43 PolarHBondContact O-N 3.19Å
44I98.1Very high96.2Very high106 Ų10633.5 Ų33.554%0.54418%0.18SC..EExtended strand (participates in β ladder)trans-113.6129.5179.7-61.4171.4000108.4D37 L38 K39D37-I44 HydrophobicContact CB-CG2 3.77Å; D37-I44 WeakPolarHBondContact OD1-CG2 3.43Å; L38-I44 CarbonylContact O-C 3.57Å; L38-I44 WeakPolarHBondContact O-CA 3.46Å; K39-I44 HydrophobicContact CB-CG1 4.42Å; K39-I44 HydrophobicContact CG-CG1 4.21Å
45F98.4Very high95.6Very high21 Ų2136.9 Ų36.99%0.09220%0.201CC..EExtended strand (participates in β ladder)trans-113.4112.3179.4-52.6-81000108.5M15 L38 T40 R42 K134 A135 V138M15-F45 HydrophobicContact CE-CE2 4.3Å; M15-F45 HydrophobicContact CE-CZ 4.37Å; L38-F45 HydrophobicContact CB-CB 4.49Å; L38-F45 HydrophobicContact CD2-CD2 4.11Å; L38-F45 PolarHBondContact N-O 3.31Å; L38-F45 WeakPolarHBondContact O-CD2 3.31Å; L38-F45 PolarHBondContact O-N 2.92Å; T40-F45 HydrophobicContact CG2-CD2 4.22Å; T40-F45 HydrophobicContact CG2-CE2 3.85Å; T40-F45 WeakPolarHBondContact OG1-CE2 3.32Å; R42-F45 HydrophobicContact CB-CZ 4.43Å; F45-K134 HydrophobicContact CB-CB 4.12Å; F45-K134 HydrophobicContact CD1-CB 4.42Å; F45-A135 HydrophobicContact CB-CB 4.2Å; F45-A135 HydrophobicContact CD1-CB 4.22Å; F45-A135 HydrophobicContact CD2-CB 3.39Å; F45-A135 HydrophobicContact CE2-CB 3.77Å; F45-A135 HydrophobicContact CG-CB 3.64Å; F45-A135 HydrophobicContact CZ-CB 4.33Å; F45-V138 HydrophobicContact CD1-CG2 4.37Å; F45-V138 HydrophobicContact CE1-CB 3.53Å; F45-V138 HydrophobicContact CE1-CG1 3.86Å; F45-V138 HydrophobicContact CE1-CG2 3.57Å; F45-V138 HydrophobicContact CZ-CB 3.9Å; F45-V138 HydrophobicContact CZ-CG1 3.89Å; F45-V138 HydrophobicContact CZ-CG2 4.41Å
46R98.7Very high94.9Very high117 Ų11736 Ų3644%0.44220%0.198SC..EExtended strand (participates in β ladder)trans-100.3135.5-174.4-178.2166.5-73.5-176.110.3111.1R23 E35 V36 D37 K134R23-R46 VanDerWaalsContact NH1-CZ 3.26Å; E35-R46 HydrophobicContact CG-CG 3.74Å; E35-R46 VanDerWaalsContact OE1-CD 3.26Å; E35-R46 WeakPolarHBondContact OE1-CD 3.22Å; E35-R46 IonicContact OE1-NE 3.22Å; E35-R46 IonicContact OE2-CZ 3.32Å; E35-R46 IonicContact OE2-NE 2.9Å; E35-R46 PolarHBondContact OE2-NE 3.46Å; E35-R46 IonicContact OE2-NH1 3.56Å; V36-R46 CarbonylContact O-C 3.57Å; V36-R46 VanDerWaalsContact O-CA 3.3Å; V36-R46 WeakPolarHBondContact O-CA 3.44Å; D37-R46 WeakPolarHBondContact OD1-CB 3.43Å; D37-R46 IonicContact OD1-CZ 2.93Å; D37-R46 IonicContact OD1-NE 2.74Å; D37-R46 PolarHBondContact OD1-NE 3.28Å; D37-R46 IonicContact OD1-NH2 3.42Å; D37-R46 PolarHBondContact OD1-NH2 3.04Å; D37-R46 IonicContact OD2-CZ 2.89Å; D37-R46 IonicContact OD2-NE 3.25Å; D37-R46 IonicContact OD2-NH2 2.79Å; D37-R46 PolarHBondContact OD2-NH2 3.49Å; R46-K134 WeakPolarHBondContact O-CD 3.32Å; R46-K134 WeakPolarHBondContact O-CE 3.5Å; R46-K134 PolarHBondContact O-NZ 3.11Å
47A98.8Very high94.5Very high0 Ų041.4 Ų41.40%023%0.226CC..EExtended strand (participates in β ladder)trans-134.5140.9168.500000112.3E35 V36 L130 A131 D397E35-A47 CarbonylContact C-O 3.52Å; E35-A47 WeakPolarHBondContact CA-O 3.39Å; V36-A47 PolarHBondContact N-O 3.48Å; V36-A47 PolarHBondContact O-N 2.93Å; A47-L130 HydrophobicContact CB-CB 3.45Å; A47-L130 VanDerWaalsContact CB-CB 3.45Å; A47-L130 HydrophobicContact CB-CD1 4.39Å; A47-A131 HydrophobicContact CB-CB 4.06Å; A47-D397 WeakPolarHBondContact CA-OD2 3.41Å
48A98.6Very high94.2Very high7 Ų744 Ų446%0.05824%0.237CC..EExtended strand (participates in β ladder)trans-119.6146.4175.600000111.4I25 V34 E35 T395 D397I25-A48 HydrophobicContact CD1-CB 3.85Å; V34-A48 WeakPolarHBondContact O-CA 3.43Å; E35-A48 HydrophobicContact CB-CB 4.47Å; A48-T395 HydrophobicContact CB-CG2 3.87Å; A48-D397 HydrophobicContact CB-CB 4.23Å; A48-D397 PolarHBondContact N-OD2 3.02Å
49V98.4Very high94Very high0 Ų045.1 Ų45.10%024%0.243CC..  trans-104.5128.1-170.6179.10000110.7T33 V34 N123 L126 G127T33-V49 WeakPolarHBondContact CG2-O 3.38Å; T33-V49 PolarHBondContact OG1-O 2.68Å; V34-V49 HydrophobicContact CB-CB 4.49Å; V34-V49 HydrophobicContact CB-CG2 4.46Å; V34-V49 PolarHBondContact O-N 3.35Å; V49-N123 HydrophobicContact CG1-CB 3.91Å; V49-L126 HydrophobicContact CG1-CD2 3.87Å; V49-L126 HydrophobicContact CG2-CB 4.44Å; V49-L126 HydrophobicContact CG2-CG 4.36Å; V49-G127 VanDerWaalsContact CG2-CA 3.43Å
50P97.7Very high93.9Very high9 Ų941.6 Ų41.66%0.05823%0.23CC..  trans-80.4171.417535-36.6000112N364 R391 G393 E394P50-N364 HydrophobicContact CG-CB 4.31Å; P50-N364 PolarHBondContact O-ND2 2.9Å; P50-R391 HydrophobicContact CB-CB 4.04Å; P50-R391 HydrophobicContact CB-CG 3.94Å; P50-R391 HydrophobicContact CG-CG 4.06Å; P50-G393 CarbonylContact C-O 3.54Å; P50-G393 VanDerWaalsContact CA-O 3.27Å; P50-G393 WeakPolarHBondContact CA-O 3.48Å; P50-G393 WeakPolarHBondContact CB-O 3.26Å; P50-E394 WeakPolarHBondContact CB-OE2 3.18Å
51S96.2Very high93.9Very high1 Ų144.8 Ų44.81%0.00725%0.246CC..BIsolated β-bridgetrans-142.9144.5-174.4-176.30000112.2R29 E62 R64 R391 G393R29-S51 PolarHBondContact NH2-OG 2.99Å; S51-E62 WeakPolarHBondContact CB-OE1 3.37Å; S51-E62 VanDerWaalsContact OG-CD 3.31Å; S51-E62 PolarHBondContact OG-OE1 3.27Å; S51-E62 PolarHBondContact OG-OE2 3.48Å; S51-R64 PolarHBondContact OG-NH2 3.24Å; S51-R391 WeakPolarHBondContact O-CB 3.43Å; S51-G393 PolarHBondContact N-O 3.4Å; S51-G393 CarbonylContact O-C 3.49Å; S51-G393 WeakPolarHBondContact O-CA 3.35Å; S51-G393 PolarHBondContact O-N 3.29Å
52G91.9Very high94Very high9 Ų942.1 Ų42.19%0.09322%0.223CC..  trans-85.1159.8177.500000115R29 R391R29-G52 VanDerWaalsContact NH1-C 3.32Å; R29-G52 PolarHBondContact NH1-O 2.8Å; R29-G52 PolarHBondContact NH2-O 3.36Å; G52-R391 VanDerWaalsContact CA-NH2 3.35Å
53A87.4Confident94.2Very high44 Ų4437.5 Ų37.536%0.36421%0.207SC..SBendtrans-102.1-57.4166.600000109.6R29 S392R29-A53 VanDerWaalsContact NH1-CA 3.28Å; A53-S392 WeakPolarHBondContact CB-OG 3.29Å; A53-S392 PolarHBondContact N-OG 3.37Å
54S80.6Confident94.2Very high13 Ų1337.9 Ų37.99%0.09120%0.199CC..SBendtrans-88.9138.4159.6171.60000109E264 R391S54-E264 WeakPolarHBondContact CB-OE1 3.47Å; S54-E264 PolarHBondContact OG-OE1 3.13Å; S54-R391 PolarHBondContact O-NH2 2.96Å
55T86Confident94.2Very high72 Ų7234.3 Ų34.344%0.44218%0.181SC..  trans-142.6130.8-176.157.70000109.4E59T55-E59 WeakPolarHBondContact CA-OE1 3.42Å
56G83.6Confident94.2Very high4 Ų435.7 Ų35.74%0.04120%0.201CC..  trans-61.1146.2169.600000112.1H58 E59 Q317 D338G56-H58 PolarHBondContact O-N 3.1Å; G56-E59 PolarHBondContact N-OE1 2.74Å; G56-E59 WeakPolarHBondContact O-CG 3.4Å; G56-E59 PolarHBondContact O-N 3.47Å; G56-Q317 VanDerWaalsContact CA-OE1 3.27Å; G56-D338 VanDerWaalsContact CA-OD1 3.3Å; G56-D338 WeakPolarHBondContact CA-OD1 3.16Å; G56-D338 PolarHBondContact N-OD1 2.97Å
57I90.7Very high94.1Very high115 Ų11533.4 Ų33.459%0.5920%0.197SC*.THydrogen-bonded Turntrans-68.3-9.4-176.567.3178.9000113.3Q317I57-Q317 VanDerWaalsContact CD1-NE2 3.34Å; I57-Q317 VanDerWaalsContact CG1-NE2 3.29Å; I57-Q317 VanDerWaalsContact CG2-NE2 3.35Å; I57-Q317 VanDerWaalsContact N-OE1 3.08Å
58H92.6Very high94Very high67 Ų6741 Ų4131%0.3123%0.23SC..THydrogen-bonded Turntrans-109.37.9-178.3-56.2-67.1000113.7G56 D318 C341 R346G56-H58 PolarHBondContact O-N 3.1Å; H58-D318 IonicContact NE2-OD1 2.6Å; H58-D318 IonicContact NE2-OD2 3.92Å; H58-C341 HydrophobicContact CB-CB 4.48Å; H58-R346 PolarHBondContact CD2-NH1 2.98Å; H58-R346 PolarHBondContact CE1-NH1 2.9Å; H58-R346 PolarHBondContact NE2-NH1 3.17Å
59E94.9Very high94Very high24 Ų2445 Ų4511%0.11226%0.258CS..SBendtrans-63.4152.8172.3-68.2-169.3-164.900111.3T55 G56 C341 Q365 R391T55-E59 WeakPolarHBondContact CA-OE1 3.42Å; G56-E59 PolarHBondContact N-OE1 2.74Å; G56-E59 WeakPolarHBondContact O-CG 3.4Å; G56-E59 PolarHBondContact O-N 3.47Å; E59-C341 HydrophobicContact CG-CB 4.25Å; E59-Q365 VanDerWaalsContact CD-CG 3.49Å; E59-Q365 HydrophobicContact CG-CB 4.12Å; E59-Q365 HydrophobicContact CG-CG 3.8Å; E59-Q365 PolarHBondContact OE1-NE2 3.07Å; E59-R391 IonicContact OE1-CZ 2.73Å; E59-R391 IonicContact OE1-NH1 3.65Å; E59-R391 IonicContact OE1-NH2 3.58Å; E59-R391 PolarHBondContact OE1-NH2 3Å; E59-R391 IonicContact OE2-CZ 3.2Å; E59-R391 IonicContact OE2-NH1 3.59Å; E59-R391 PolarHBondContact OE2-NH1 3.17Å; E59-R391 IonicContact OE2-NH2 2.79Å; E59-R391 PolarHBondContact OE2-NH2 3.34Å
60A95.9Very high93.9Very high13 Ų1350.6 Ų50.611%0.10728%0.284CS..  trans-61.6147.216800000110.8E62 K117 A122 Q365A60-E62 PolarHBondContact O-N 3.02Å; A60-E62 VanDerWaalsContact O-N 3.13Å; A60-K117 HydrophobicContact CB-CD 4.06Å; A60-A122 HydrophobicContact CB-CB 3.52Å; A60-Q365 VanDerWaalsContact CB-O 3.23Å; A60-Q365 WeakPolarHBondContact CB-O 3.42Å; A60-Q365 PolarHBondContact N-O 3.07Å
61L96.9Very high93.9Very high72 Ų7253.7 Ų53.738%0.37730%0.297SS..  trans-71.7111.5-171-177.770.5000111.5M63 N116 A122L61-M63 PolarHBondContact O-N 2.58Å; L61-N116 PolarHBondContact N-O 3.32Å; L61-A122 VanDerWaalsContact O-CB 3.3Å; L61-A122 WeakPolarHBondContact O-CB 3.34Å; L61-A122 PolarHBondContact O-N 3.26Å
62E97.2Very high93.9Very high39 Ų3960.1 Ų60.118%0.18233%0.331CS..  trans-69.6110.9161.1-175.4-172.5-131.700109.8S51 A60 R64 N123S51-E62 WeakPolarHBondContact CB-OE1 3.37Å; S51-E62 VanDerWaalsContact OG-CD 3.31Å; S51-E62 PolarHBondContact OG-OE1 3.27Å; S51-E62 PolarHBondContact OG-OE2 3.48Å; A60-E62 PolarHBondContact O-N 3.02Å; A60-E62 VanDerWaalsContact O-N 3.13Å; E62-R64 VanDerWaalsContact CD-CZ 3.46Å; E62-R64 PolarHBondContact O-N 3.31Å; E62-R64 IonicContact OE1-CZ 3.4Å; E62-R64 IonicContact OE1-NE 3.63Å; E62-R64 IonicContact OE1-NH2 3.18Å; E62-R64 PolarHBondContact OE1-NH2 3.21Å; E62-R64 IonicContact OE2-CZ 2.97Å; E62-R64 VanDerWaalsContact OE2-CZ 3.25Å; E62-R64 IonicContact OE2-NE 3.73Å; E62-R64 PolarHBondContact OE2-NE 3.08Å; E62-R64 IonicContact OE2-NH2 2.57Å; E62-R64 PolarHBondContact OE2-NH2 2.87Å; E62-N123 HydrophobicContact CG-CB 4.25Å
63M97.9Very high94.1Very high23 Ų2360 Ų6011%0.11333%0.33CS..  trans-78119.1-177.2-178.5171.1-6700111.2L61 K78 A79 N82 S118 K119 N123L61-M63 PolarHBondContact O-N 2.58Å; M63-K78 HydrophobicContact CG-CB 4.07Å; M63-K78 HydrophobicContact SD-CB 3.82Å; M63-A79 HydrophobicContact CB-CB 4.19Å; M63-A79 HydrophobicContact CG-CB 4.48Å; M63-N82 PolarHBondContact SD-ND2 3.24Å; M63-S118 VanDerWaalsContact CE-O 3.25Å; M63-S118 WeakPolarHBondContact CE-O 3.43Å; M63-K119 WeakPolarHBondContact CE-O 3.27Å; M63-N123 PolarHBondContact N-OD1 2.98Å; M63-N123 PolarHBondContact O-ND2 2.96Å; M63-N123 VanDerWaalsContact O-ND2 3.08Å
64R97.9Very high94.6Very high40 Ų4062.6 Ų62.615%0.15133%0.333CS..  trans-114.5157.1175.2-58.5-59.2-168.8161.8-9.8111.7P32 S51 E62 K74 G75 V76P32-R64 PolarHBondContact O-NH1 3.45Å; S51-R64 PolarHBondContact OG-NH2 3.24Å; E62-R64 VanDerWaalsContact CD-CZ 3.46Å; E62-R64 PolarHBondContact O-N 3.31Å; E62-R64 IonicContact OE1-CZ 3.4Å; E62-R64 IonicContact OE1-NE 3.63Å; E62-R64 IonicContact OE1-NH2 3.18Å; E62-R64 PolarHBondContact OE1-NH2 3.21Å; E62-R64 IonicContact OE2-CZ 2.97Å; E62-R64 VanDerWaalsContact OE2-CZ 3.25Å; E62-R64 IonicContact OE2-NE 3.73Å; E62-R64 PolarHBondContact OE2-NE 3.08Å; E62-R64 IonicContact OE2-NH2 2.57Å; E62-R64 PolarHBondContact OE2-NH2 2.87Å; R64-K74 PolarHBondContact NH1-O 3.26Å; R64-G75 CarbonylContact C-O 3.45Å; R64-G75 VanDerWaalsContact CA-O 3.3Å; R64-G75 WeakPolarHBondContact CA-O 3.42Å; R64-V76 VanDerWaalsContact NH1-CG1 3.27Å
65D98.2Very high95.5Very high30 Ų3062 Ų6216%0.1633%0.329CS..  trans-72.1-34.6-178.4-65.2-21.5000112.2D67 G75 V76 L77 K78D65-D67 PolarHBondContact O-N 2.98Å; D65-G75 PolarHBondContact N-O 3.29Å; D65-G75 VanDerWaalsContact OD2-CA 3.25Å; D65-G75 WeakPolarHBondContact OD2-CA 3.25Å; D65-V76 PolarHBondContact OD2-N 3.35Å; D65-V76 VanDerWaalsContact OD2-N 3.12Å; D65-L77 VanDerWaalsContact CG-N 3.33Å; D65-L77 PolarHBondContact OD1-N 3.24Å; D65-L77 WeakPolarHBondContact OD2-CB 3.32Å; D65-L77 PolarHBondContact OD2-N 2.91Å; D65-K78 WeakPolarHBondContact O-CE 3.47Å; D65-K78 PolarHBondContact O-NZ 2.68Å; D65-K78 WeakPolarHBondContact OD1-CB 3.46Å; D65-K78 WeakPolarHBondContact OD1-CG 3.3Å; D65-K78 PolarHBondContact OD1-N 3.34Å
66G97.1Very high96.1Very high50 Ų5058.6 Ų58.652%0.51531%0.308SS..  trans75.2-1.7179.200000114.7K68 G73G66-K68 PolarHBondContact O-N 2.79Å; G66-G73 WeakPolarHBondContact CA-O 3.46Å; G66-G73 PolarHBondContact N-O 2.87Å; G66-G73 VanDerWaalsContact N-O 3.07Å
67D97.7Very high96.8Very high70 Ų7063.2 Ų63.237%0.37433%0.331SS..  trans-74.3105.3176.3178.54.3000111.3D65 S69 H70 G73D65-D67 PolarHBondContact O-N 2.98Å; D67-S69 PolarHBondContact O-N 2.87Å; D67-S69 WeakPolarHBondContact OD1-CB 3.39Å; D67-S69 PolarHBondContact OD1-N 2.92Å; D67-S69 PolarHBondContact OD1-OG 2.72Å; D67-S69 PolarHBondContact OD2-OG 2.76Å; D67-S69 VanDerWaalsContact OD2-OG 3.09Å; D67-H70 PolarHBondContact O-N 2.7Å; D67-H70 VanDerWaalsContact O-N 3.16Å; D67-H70 IonicContact OD2-CE1 3.7Å; D67-H70 IonicContact OD2-CG 3.6Å; D67-H70 IonicContact OD2-ND1 2.86Å; D67-H70 PolarHBondContact OD2-ND1 2.91Å; D67-G73 WeakPolarHBondContact O-CA 3.4Å; D67-G73 PolarHBondContact O-N 2.96Å
68K96.9Very high97.1Very high159 Ų15962.9 Ų62.969%0.69133%0.325SS*.THydrogen-bonded Turntrans-63.9-20.9-179.6-67.4-62.6-177.7-177.80114.2G66 H70 L72G66-K68 PolarHBondContact O-N 2.79Å; K68-H70 VanDerWaalsContact C-N 3.29Å; K68-L72 WeakPolarHBondContact CD-O 3.4Å; K68-L72 PolarHBondContact NZ-O 3.3Å; K68-L72 VanDerWaalsContact NZ-O 3.16Å
69S97.7Very high97.4Very high90 Ų9059.7 Ų59.763%0.62931%0.311SS*.THydrogen-bonded Turntrans-75.3-19.3177.870.60000113.1D67D67-S69 PolarHBondContact O-N 2.87Å; D67-S69 WeakPolarHBondContact OD1-CB 3.39Å; D67-S69 PolarHBondContact OD1-N 2.92Å; D67-S69 PolarHBondContact OD1-OG 2.72Å; D67-S69 PolarHBondContact OD2-OG 2.76Å; D67-S69 VanDerWaalsContact OD2-OG 3.09Å
70H96.9Very high97.6Very high118 Ų11859.1 Ų59.155%0.54631%0.309SS..SBendtrans-124.5125.3179-63.891.8000111.2D67 K68 L72 G73D67-H70 PolarHBondContact O-N 2.7Å; D67-H70 VanDerWaalsContact O-N 3.16Å; D67-H70 IonicContact OD2-CE1 3.7Å; D67-H70 IonicContact OD2-CG 3.6Å; D67-H70 IonicContact OD2-ND1 2.86Å; D67-H70 PolarHBondContact OD2-ND1 2.91Å; K68-H70 VanDerWaalsContact C-N 3.29Å; H70-L72 PolarHBondContact O-N 3.2Å; H70-G73 PolarHBondContact O-N 3.33Å
71H97Very high97.8Very high75 Ų7563.9 Ų63.935%0.34733%0.327SS..G310 helixtrans50.528.9-179.6-52.8-76000113.7Q24 Y26 P32 G73 K74Q24-H71 PolarHBondContact NE2-NE2 3.29Å; Y26-H71 PolarHBondContact OH-CE1 3.17Å; P32-H71 HydrophobicContact CG-CB 3.69Å; P32-H71 VanDerWaalsContact CG-CG 3.4Å; P32-H71 WeakPolarHBondContact CG-ND1 3.36Å; H71-G73 PolarHBondContact O-N 2.83Å; H71-G73 VanDerWaalsContact O-N 3.09Å; H71-K74 VanDerWaalsContact O-CB 3.31Å; H71-K74 WeakPolarHBondContact O-CB 3.28Å; H71-K74 PolarHBondContact O-N 3.31Å
72L96.5Very high97.9Very high136 Ų13661.9 Ų61.971%0.71232%0.317SS*.G310 helixtrans56.127.4-179.2-50175.7000114K68 H70K68-L72 WeakPolarHBondContact CD-O 3.4Å; K68-L72 PolarHBondContact NZ-O 3.3Å; K68-L72 VanDerWaalsContact NZ-O 3.16Å; H70-L72 PolarHBondContact O-N 3.2Å
73G97.1Very high97.9Very high7 Ų760 Ų607%0.07231%0.308CS..G310 helixtrans88.71-176.800000114.9G66 D67 H70 H71G66-G73 WeakPolarHBondContact CA-O 3.46Å; G66-G73 PolarHBondContact N-O 2.87Å; G66-G73 VanDerWaalsContact N-O 3.07Å; D67-G73 WeakPolarHBondContact O-CA 3.4Å; D67-G73 PolarHBondContact O-N 2.96Å; H70-G73 PolarHBondContact O-N 3.33Å; H71-G73 PolarHBondContact O-N 2.83Å; H71-G73 VanDerWaalsContact O-N 3.09Å
74K97.6Very high98Very high97 Ų9761.4 Ų61.442%0.42232%0.316SS..THydrogen-bonded Turntrans-91.26.1-177.5-61.2-67.8-170.2171.90114.2R64 H71R64-K74 PolarHBondContact NH1-O 3.26Å; H71-K74 VanDerWaalsContact O-CB 3.31Å; H71-K74 WeakPolarHBondContact O-CB 3.28Å; H71-K74 PolarHBondContact O-N 3.31Å
75G98.4Very high98Very high1 Ų165.4 Ų65.41%0.0134%0.336CS..  trans-54.7156.3171.200000112.7R64 D65R64-G75 CarbonylContact C-O 3.45Å; R64-G75 VanDerWaalsContact CA-O 3.3Å; R64-G75 WeakPolarHBondContact CA-O 3.42Å; D65-G75 PolarHBondContact N-O 3.29Å; D65-G75 VanDerWaalsContact OD2-CA 3.25Å; D65-G75 WeakPolarHBondContact OD2-CA 3.25Å
76V98.6Very high98Very high0 Ų066.5 Ų66.50%034%0.344CS..  trans-127.218.8-179.4-63.40000113Q24 P32 T33 V34 R64 D65 K78 A79 V80Q24-V76 HydrophobicContact CB-CG2 4.07Å; Q24-V76 HydrophobicContact CG-CG2 3.72Å; P32-V76 HydrophobicContact CB-CG2 4.3Å; T33-V76 WeakPolarHBondContact O-CG2 3.38Å; V34-V76 HydrophobicContact CG2-CB 3.98Å; V34-V76 HydrophobicContact CG2-CG2 3.94Å; R64-V76 VanDerWaalsContact NH1-CG1 3.27Å; D65-V76 PolarHBondContact OD2-N 3.35Å; D65-V76 VanDerWaalsContact OD2-N 3.12Å; V76-K78 PolarHBondContact O-N 3.41Å; V76-A79 WeakPolarHBondContact O-CB 3.35Å; V76-A79 PolarHBondContact O-N 2.96Å; V76-A79 VanDerWaalsContact O-N 3.08Å; V76-V80 HydrophobicContact CG2-CG2 4.33Å; V76-V80 WeakPolarHBondContact O-CG2 3.17Å; V76-V80 PolarHBondContact O-N 2.95Å
77L98.6Very high98.1Very high101 Ų10164.1 Ų64.153%0.52932%0.32SS..Hα-helixtrans-63.4-28.4-176.9-64.9179.5000112.7Q24 D65 V80 K81Q24-L77 HydrophobicContact CB-CD2 4.09Å; D65-L77 VanDerWaalsContact CG-N 3.33Å; D65-L77 PolarHBondContact OD1-N 3.24Å; D65-L77 WeakPolarHBondContact OD2-CB 3.32Å; D65-L77 PolarHBondContact OD2-N 2.91Å; L77-V80 PolarHBondContact O-N 3.3Å; L77-K81 WeakPolarHBondContact O-CB 3.26Å; L77-K81 PolarHBondContact O-N 3.21Å
78K98.7Very high98.1Very high108 Ų10861.4 Ų61.447%0.4731%0.307SS..Hα-helixtrans-61.1-47.2170.5-71.9177.7-174.7169.20112M63 D65 V76 K81 N82M63-K78 HydrophobicContact CG-CB 4.07Å; M63-K78 HydrophobicContact SD-CB 3.82Å; D65-K78 WeakPolarHBondContact O-CE 3.47Å; D65-K78 PolarHBondContact O-NZ 2.68Å; D65-K78 WeakPolarHBondContact OD1-CB 3.46Å; D65-K78 WeakPolarHBondContact OD1-CG 3.3Å; D65-K78 PolarHBondContact OD1-N 3.34Å; V76-K78 PolarHBondContact O-N 3.41Å; K78-K81 PolarHBondContact O-N 3.48Å; K78-N82 VanDerWaalsContact O-CG 3.32Å; K78-N82 PolarHBondContact O-N 3.44Å
79A98.7Very high98.2Very high0 Ų057 Ų570%030%0.295CS..Hα-helixtrans-65.1-43.3177.500000111.3V34 M63 V76 K81 N82 I83 A124V34-A79 HydrophobicContact CG2-CB 3.98Å; M63-A79 HydrophobicContact CB-CB 4.19Å; M63-A79 HydrophobicContact CG-CB 4.48Å; V76-A79 WeakPolarHBondContact O-CB 3.35Å; V76-A79 PolarHBondContact O-N 2.96Å; V76-A79 VanDerWaalsContact O-N 3.08Å; A79-K81 VanDerWaalsContact C-N 3.33Å; A79-K81 PolarHBondContact O-N 2.92Å; A79-N82 WeakPolarHBondContact O-CB 3.43Å; A79-N82 PolarHBondContact O-N 2.97Å; A79-I83 WeakPolarHBondContact O-CG1 3.49Å; A79-I83 PolarHBondContact O-N 3.19Å; A79-A124 HydrophobicContact CB-CB 4.33Å
80V98.8Very high98.2Very high13 Ų1353.5 Ų53.58%0.07927%0.271CS..Hα-helixtrans-59.1-44.6174.8169.80000111.2A22 V34 V76 L77 I83 N84A22-V80 HydrophobicContact CB-CG1 4.12Å; A22-V80 WeakPolarHBondContact O-CG1 3.39Å; V34-V80 HydrophobicContact CG2-CG2 4.33Å; V76-V80 HydrophobicContact CG2-CG2 4.33Å; V76-V80 WeakPolarHBondContact O-CG2 3.17Å; V76-V80 PolarHBondContact O-N 2.95Å; L77-V80 PolarHBondContact O-N 3.3Å; V80-I83 PolarHBondContact O-N 2.88Å; V80-N84 WeakPolarHBondContact CG1-ND2 3.27Å; V80-N84 PolarHBondContact O-N 2.92Å; V80-N84 PolarHBondContact O-ND2 2.97Å
81K98.8Very high98.2Very high112 Ų11248 Ų4849%0.48725%0.246SC..Hα-helixtrans-61.2-44.9176-173-179.1-179.1-178.40111.4L77 K78 A79 I83 N84 E85L77-K81 WeakPolarHBondContact O-CB 3.26Å; L77-K81 PolarHBondContact O-N 3.21Å; K78-K81 PolarHBondContact O-N 3.48Å; A79-K81 VanDerWaalsContact C-N 3.33Å; A79-K81 PolarHBondContact O-N 2.92Å; K81-I83 VanDerWaalsContact C-N 3.28Å; K81-I83 PolarHBondContact O-N 2.93Å; K81-N84 PolarHBondContact O-N 3.15Å; K81-E85 VanDerWaalsContact CE-OE1 3.28Å; K81-E85 WeakPolarHBondContact CE-OE1 3.49Å; K81-E85 WeakPolarHBondContact CE-OE2 3.3Å; K81-E85 VanDerWaalsContact CG-CD 3.49Å; K81-E85 HydrophobicContact CG-CG 4.13Å; K81-E85 WeakPolarHBondContact CG-OE1 3.38Å; K81-E85 IonicContact NZ-OE2 3.62Å; K81-E85 WeakPolarHBondContact O-CB 3.46Å; K81-E85 PolarHBondContact O-N 3.49Å
82N98.8Very high98.1Very high30 Ų3050.9 Ų50.916%0.1626%0.257CS..Hα-helixtrans-59.2-38.6176-73.6-17.8000112.1M63 K78 A79 V86 I87 K119 L120M63-N82 PolarHBondContact SD-ND2 3.24Å; K78-N82 VanDerWaalsContact O-CG 3.32Å; K78-N82 PolarHBondContact O-N 3.44Å; A79-N82 WeakPolarHBondContact O-CB 3.43Å; A79-N82 PolarHBondContact O-N 2.97Å; N82-V86 WeakPolarHBondContact O-CA 3.21Å; N82-V86 VanDerWaalsContact O-CB 3.27Å; N82-V86 WeakPolarHBondContact O-CB 3.16Å; N82-V86 PolarHBondContact O-N 3.16Å; N82-V86 VanDerWaalsContact O-N 3.14Å; N82-I87 PolarHBondContact O-N 2.95Å; N82-K119 PolarHBondContact ND2-O 3.45Å; N82-L120 HydrophobicContact CB-CD2 4.28Å; N82-L120 WeakPolarHBondContact ND2-CA 3.32Å; N82-L120 PolarHBondContact ND2-O 2.93Å
83I98.8Very high98Very high0 Ų048.9 Ų48.90%025%0.254CS..Iπ-helixtrans-65.9-52.7174.7-63.2161.7000110.8A22 V34 V36 A79 V80 K81 I87 A88 A124 V128A22-I83 HydrophobicContact CB-CB 3.62Å; A22-I83 HydrophobicContact CB-CD1 3.6Å; A22-I83 HydrophobicContact CB-CG1 4.22Å; A22-I83 HydrophobicContact CB-CG2 3.6Å; V34-I83 HydrophobicContact CG1-CD1 3.55Å; V36-I83 HydrophobicContact CG2-CD1 3.68Å; A79-I83 WeakPolarHBondContact O-CG1 3.49Å; A79-I83 PolarHBondContact O-N 3.19Å; V80-I83 PolarHBondContact O-N 2.88Å; K81-I83 VanDerWaalsContact C-N 3.28Å; K81-I83 PolarHBondContact O-N 2.93Å; I83-I87 HydrophobicContact CG1-CD1 4.15Å; I83-I87 PolarHBondContact O-N 3.17Å; I83-A88 WeakPolarHBondContact O-CB 3.49Å; I83-A88 PolarHBondContact O-N 3.2Å; I83-A124 HydrophobicContact CD1-CB 3.99Å; I83-A124 HydrophobicContact CG1-CB 3.65Å; I83-V128 HydrophobicContact CG1-CG2 4.19Å; I83-V128 HydrophobicContact CG2-CG2 3.76Å
84N98.8Very high97.9Very high52 Ų5254.3 Ų54.328%0.27828%0.276SS..Iπ-helixtrans-69.7-38.7-171.9-71.5-25.1000113.6A22 V80 K81 P89A22-N84 PolarHBondContact N-OD1 2.91Å; A22-N84 PolarHBondContact O-ND2 3.15Å; V80-N84 WeakPolarHBondContact CG1-ND2 3.27Å; V80-N84 PolarHBondContact O-N 2.92Å; V80-N84 PolarHBondContact O-ND2 2.97Å; K81-N84 PolarHBondContact O-N 3.15Å; N84-P89 WeakPolarHBondContact O-CD 3.44Å
85E98.6Very high97.6Very high124 Ų12452 Ų5258%0.57928%0.281SS*.Iπ-helixtrans-102.7-18.6-171.1-62.5-177.9-164.200113.6K81K81-E85 VanDerWaalsContact CE-OE1 3.28Å; K81-E85 WeakPolarHBondContact CE-OE1 3.49Å; K81-E85 WeakPolarHBondContact CE-OE2 3.3Å; K81-E85 VanDerWaalsContact CG-CD 3.49Å; K81-E85 HydrophobicContact CG-CG 4.13Å; K81-E85 WeakPolarHBondContact CG-OE1 3.38Å; K81-E85 IonicContact NZ-OE2 3.62Å; K81-E85 WeakPolarHBondContact O-CB 3.46Å; K81-E85 PolarHBondContact O-N 3.49Å
86V98.7Very high97.5Very high54 Ų5453.8 Ų53.833%0.32729%0.288SS..Iπ-helixtrans-118.7-59.4-176.2-170.60000111.5N82 A90 L111 L120N82-V86 WeakPolarHBondContact O-CA 3.21Å; N82-V86 VanDerWaalsContact O-CB 3.27Å; N82-V86 WeakPolarHBondContact O-CB 3.16Å; N82-V86 PolarHBondContact O-N 3.16Å; N82-V86 VanDerWaalsContact O-N 3.14Å; V86-A90 WeakPolarHBondContact O-CB 2.8Å; V86-A90 PolarHBondContact O-N 3.27Å; V86-L111 HydrophobicContact CG1-CD2 4.11Å; V86-L111 HydrophobicContact CG1-CG 4.37Å; V86-L120 HydrophobicContact CB-CD2 4.36Å; V86-L120 HydrophobicContact CG1-CD2 4.01Å
87I98.7Very high97.4Very high0 Ų055 Ų550%029%0.293CS..Iπ-helixtrans-68.6-47.6-175.3-61.5172.5000111.1N82 I83 A90 L91 M108 L111 L120 A124 V128N82-I87 PolarHBondContact O-N 2.95Å; I83-I87 HydrophobicContact CG1-CD1 4.15Å; I83-I87 PolarHBondContact O-N 3.17Å; I87-A90 PolarHBondContact O-N 3.06Å; I87-L91 HydrophobicContact CG2-CD1 3.62Å; I87-L91 HydrophobicContact CG2-CG 4.07Å; I87-L91 WeakPolarHBondContact O-CG 3.28Å; I87-L91 PolarHBondContact O-N 3.27Å; I87-M108 HydrophobicContact CG2-CG 4.15Å; I87-M108 HydrophobicContact CG2-SD 3.81Å; I87-L111 HydrophobicContact CG1-CD2 4.41Å; I87-L120 HydrophobicContact CD1-CD1 4.14Å; I87-L120 HydrophobicContact CG1-CD1 3.99Å; I87-A124 HydrophobicContact CD1-CB 4.16Å; I87-V128 HydrophobicContact CG2-CG1 4.31Å; I87-V128 HydrophobicContact CG2-CG2 4.11Å
88A98.3Very high97.3Very high13 Ų1350.1 Ų50.111%0.10727%0.268CS..Hα-helixtrans-61.2-49.9-175.900000112.9L20 I83 A90 K92L20-A88 HydrophobicContact CB-CB 3.58Å; L20-A88 HydrophobicContact CD1-CB 4.33Å; I83-A88 WeakPolarHBondContact O-CB 3.49Å; I83-A88 PolarHBondContact O-N 3.2Å; A88-A90 VanDerWaalsContact C-N 3.34Å; A88-A90 PolarHBondContact O-N 2.91Å; A88-K92 WeakPolarHBondContact O-CB 3.47Å; A88-K92 PolarHBondContact O-N 3.36Å; A88-K92 VanDerWaalsContact O-N 3.08Å
89P97.7Very high97.2Very high67 Ų6746.8 Ų46.844%0.43526%0.257SS..Hα-helixtrans-62.1-40174.3-24.236000112.7N84 K92 S93N84-P89 WeakPolarHBondContact O-CD 3.44Å; P89-K92 PolarHBondContact O-N 2.82Å; P89-S93 WeakPolarHBondContact O-CB 3.49Å; P89-S93 PolarHBondContact O-N 3.14Å
90A97.9Very high97.2Very high16 Ų1650.9 Ų50.913%0.13228%0.276CS..Hα-helixtrans-64.4-47.4-178.900000112V86 I87 A88 S93 K94 F107 L111V86-A90 WeakPolarHBondContact O-CB 2.8Å; V86-A90 PolarHBondContact O-N 3.27Å; I87-A90 PolarHBondContact O-N 3.06Å; A88-A90 VanDerWaalsContact C-N 3.34Å; A88-A90 PolarHBondContact O-N 2.91Å; A90-S93 PolarHBondContact O-N 3.12Å; A90-S93 PolarHBondContact O-OG 2.94Å; A90-K94 WeakPolarHBondContact O-CG 3.37Å; A90-K94 PolarHBondContact O-N 3.1Å; A90-K94 VanDerWaalsContact O-N 3.16Å; A90-F107 HydrophobicContact CB-CE1 3.78Å; A90-F107 HydrophobicContact CB-CZ 3.93Å; A90-L111 HydrophobicContact CB-CD2 3.79Å
91L97.2Very high97.2Very high2 Ų250.3 Ų50.31%0.0127%0.272CS..Hα-helixtrans-64.9-42.3177.5-72.9178.1000112.3I17 L20 I87 S93 K94 G95 F96 I104 F107 M108 V128I17-L91 HydrophobicContact CD1-CB 4.31Å; I17-L91 HydrophobicContact CD1-CD1 4.22Å; L20-L91 HydrophobicContact CD1-CB 4.4Å; L20-L91 HydrophobicContact CD1-CD1 3.68Å; I87-L91 HydrophobicContact CG2-CD1 3.62Å; I87-L91 HydrophobicContact CG2-CG 4.07Å; I87-L91 WeakPolarHBondContact O-CG 3.28Å; I87-L91 PolarHBondContact O-N 3.27Å; L91-S93 VanDerWaalsContact C-N 3.29Å; L91-S93 PolarHBondContact O-N 3.18Å; L91-K94 PolarHBondContact O-N 2.95Å; L91-G95 PolarHBondContact O-N 2.9Å; L91-F96 HydrophobicContact CD2-CD2 3.9Å; L91-F96 HydrophobicContact CD2-CE2 4.24Å; L91-I104 HydrophobicContact CD1-CG2 4.23Å; L91-I104 HydrophobicContact CD2-CG2 3.87Å; L91-F107 HydrophobicContact CD2-CD1 3.58Å; L91-F107 HydrophobicContact CD2-CE1 4.02Å; L91-F107 HydrophobicContact CG-CD1 4.48Å; L91-M108 HydrophobicContact CD1-CG 4.49Å; L91-M108 HydrophobicContact CD1-SD 4.22Å; L91-M108 HydrophobicContact CD2-CG 4.46Å; L91-V128 HydrophobicContact CD1-CG1 3.71Å
92K94.1Very high97.1Very high135 Ų13547.4 Ų47.459%0.58727%0.269SS*.Hα-helixtrans-60.3-40.3175.3-173.3170.3-177.31620111.9M18 A88 P89 K94 G95M18-K92 PolarHBondContact O-NZ 3.48Å; A88-K92 WeakPolarHBondContact O-CB 3.47Å; A88-K92 PolarHBondContact O-N 3.36Å; A88-K92 VanDerWaalsContact O-N 3.08Å; P89-K92 PolarHBondContact O-N 2.82Å; K92-K94 VanDerWaalsContact C-N 3.3Å; K92-K94 PolarHBondContact O-N 3.45Å; K92-G95 PolarHBondContact O-N 3.17Å
93S95Very high97.1Very high94 Ų9447.9 Ų47.966%0.65728%0.277SS*.Hα-helixtrans-66.7-29.6177.978.20000113.6P89 A90 L91P89-S93 WeakPolarHBondContact O-CB 3.49Å; P89-S93 PolarHBondContact O-N 3.14Å; A90-S93 PolarHBondContact O-N 3.12Å; A90-S93 PolarHBondContact O-OG 2.94Å; L91-S93 VanDerWaalsContact C-N 3.29Å; L91-S93 PolarHBondContact O-N 3.18Å
94K94.9Very high97.1Very high121 Ų12147.9 Ų47.953%0.52628%0.277SS..Hα-helixtrans-77.8-23.2177.7-71.8-63.6-174.3-175.80113.2A90 L91 K92 F96 F107A90-K94 WeakPolarHBondContact O-CG 3.37Å; A90-K94 PolarHBondContact O-N 3.1Å; A90-K94 VanDerWaalsContact O-N 3.16Å; L91-K94 PolarHBondContact O-N 2.95Å; K92-K94 VanDerWaalsContact C-N 3.3Å; K92-K94 PolarHBondContact O-N 3.45Å; K94-F96 VanDerWaalsContact C-N 3.28Å; K94-F96 HydrophobicContact CB-CD2 3.52Å; K94-F96 HydrophobicContact CB-CE2 3.39Å; K94-F96 HydrophobicContact CB-CG 4.18Å; K94-F96 HydrophobicContact CB-CZ 3.94Å; K94-F96 HydrophobicContact CD-CE2 4.49Å; K94-F96 HydrophobicContact CD-CZ 4.5Å; K94-F96 HydrophobicContact CG-CD2 4.28Å; K94-F96 HydrophobicContact CG-CE2 3.67Å; K94-F96 HydrophobicContact CG-CZ 4.14Å; K94-F96 PolarHBondContact O-N 3.5Å; K94-F107 HydrophobicContact CD-CE2 4.16Å; K94-F107 HydrophobicContact CD-CZ 4.34Å; K94-F107 HydrophobicContact CG-CD1 4.46Å; K94-F107 HydrophobicContact CG-CD2 4.36Å; K94-F107 HydrophobicContact CG-CE1 3.98Å; K94-F107 HydrophobicContact CG-CE2 3.91Å; K94-F107 HydrophobicContact CG-CZ 3.67Å
95G92.4Very high97.1Very high50 Ų5045.4 Ų45.452%0.51526%0.264SS..THydrogen-bonded Turntrans64.132.9179.700000113L91 K92L91-G95 PolarHBondContact O-N 2.9Å; K92-G95 PolarHBondContact O-N 3.17Å
96F95.3Very high97.1Very high38 Ų3842.4 Ų42.417%0.16725%0.254CS..  trans-65.2142.4177.3-68.6-60.3000111.6L91 K94 A103 I104 F107L91-F96 HydrophobicContact CD2-CD2 3.9Å; L91-F96 HydrophobicContact CD2-CE2 4.24Å; K94-F96 VanDerWaalsContact C-N 3.28Å; K94-F96 HydrophobicContact CB-CD2 3.52Å; K94-F96 HydrophobicContact CB-CE2 3.39Å; K94-F96 HydrophobicContact CB-CG 4.18Å; K94-F96 HydrophobicContact CB-CZ 3.94Å; K94-F96 HydrophobicContact CD-CE2 4.49Å; K94-F96 HydrophobicContact CD-CZ 4.5Å; K94-F96 HydrophobicContact CG-CD2 4.28Å; K94-F96 HydrophobicContact CG-CE2 3.67Å; K94-F96 HydrophobicContact CG-CZ 4.14Å; K94-F96 PolarHBondContact O-N 3.5Å; F96-A103 HydrophobicContact CD1-CB 4.47Å; F96-A103 HydrophobicContact CE1-CB 4.15Å; F96-I104 HydrophobicContact CB-CD1 3.9Å; F96-I104 HydrophobicContact CB-CG1 3.61Å; F96-I104 HydrophobicContact CD2-CG1 3.86Å; F96-I104 HydrophobicContact CG-CG1 3.8Å; F96-F107 HydrophobicContact CE2-CB 3.81Å; F96-F107 AromaticContact CE2-CD1 3.88Å; F96-F107 HydrophobicContact CE2-CD1 3.88Å; F96-F107 HydrophobicContact CE2-CD2 4.4Å; F96-F107 AromaticContact CE2-CG 3.76Å; F96-F107 HydrophobicContact CE2-CG 3.76Å; F96-F107 HydrophobicContact CZ-CB 4.07Å; F96-F107 HydrophobicContact CZ-CG 4.24Å
97E95.4Very high97.1Very high24 Ų2441.3 Ų41.311%0.11225%0.245CC..BIsolated β-bridgetrans-75.8138.5166.6-73.1-64.5112.900109.8E14 M15 S16 T99 Q100 I104E14-E97 VanDerWaalsContact C-OE2 3.31Å; E14-E97 VanDerWaalsContact CA-OE2 3.23Å; E14-E97 WeakPolarHBondContact CA-OE2 3.31Å; E14-E97 VanDerWaalsContact CB-OE1 3.31Å; E14-E97 WeakPolarHBondContact CB-OE1 3.23Å; E14-E97 HydrophobicContact CG-CG 4.32Å; M15-E97 PolarHBondContact N-OE1 3.34Å; M15-E97 PolarHBondContact N-OE2 3.35Å; S16-E97 PolarHBondContact N-OE1 3.24Å; E97-T99 PolarHBondContact O-N 3.4Å; E97-Q100 HydrophobicContact CB-CG 4Å; E97-Q100 WeakPolarHBondContact O-CB 3.26Å; E97-Q100 PolarHBondContact O-N 3.12Å; E97-I104 WeakPolarHBondContact O-CD1 3.3Å
98V96.8Very high97.1Very high0 Ų041.3 Ų41.30%025%0.245CC..THydrogen-bonded Turntrans-64-14.3-178.4-60.50000113.6M15 I17 L38 T40 Q100 V132 A135 H139M15-V98 HydrophobicContact CB-CG2 4.49Å; M15-V98 HydrophobicContact CE-CG2 3.37Å; M15-V98 PolarHBondContact O-N 3.35Å; I17-V98 HydrophobicContact CG1-CG1 3.74Å; L38-V98 HydrophobicContact CD2-CG1 4.16Å; T40-V98 HydrophobicContact CG2-CG1 4.01Å; V98-Q100 VanDerWaalsContact C-N 3.27Å; V98-V132 WeakPolarHBondContact O-CG1 3.21Å; V98-A135 HydrophobicContact CB-CB 3.95Å; V98-A135 HydrophobicContact CG1-CB 3.97Å; V98-A135 HydrophobicContact CG2-CB 4Å; V98-H139 HydrophobicContact CG2-CB 4.1Å
99T97.5Very high97.1Very high38 Ų3843 Ų4323%0.23325%0.252CS..THydrogen-bonded Turntrans-78.4-11.117454.90000113.6E97 Q101 H139 K140 Y147E97-T99 PolarHBondContact O-N 3.4Å; T99-Q101 PolarHBondContact O-N 3.05Å; T99-Q101 VanDerWaalsContact O-N 3.11Å; T99-H139 HydrophobicContact CG2-CB 3.99Å; T99-H139 WeakPolarHBondContact CG2-CD2 3.41Å; T99-K140 HydrophobicContact CG2-CD 4.43Å; T99-K140 HydrophobicContact CG2-CG 4.04Å; T99-Y147 WeakPolarHBondContact CA-OH 3.24Å; T99-Y147 PolarHBondContact O-OH 3.23Å
100Q97.7Very high97.1Very high85 Ų8546.4 Ų46.440%0.39726%0.262SS..  trans-86.848.8179.2-60.4176.9-66.700111.7E97 V98 A102 A103 I104E97-Q100 HydrophobicContact CB-CG 4Å; E97-Q100 WeakPolarHBondContact O-CB 3.26Å; E97-Q100 PolarHBondContact O-N 3.12Å; V98-Q100 VanDerWaalsContact C-N 3.27Å; Q100-A102 VanDerWaalsContact C-N 3.32Å; Q100-A102 PolarHBondContact O-N 3.35Å; Q100-A103 HydrophobicContact CB-CB 4.08Å; Q100-A103 PolarHBondContact O-N 2.93Å; Q100-I104 PolarHBondContact O-N 3.37Å
101Q98.6Very high97.2Very high2 Ų247.6 Ų47.61%0.00927%0.266CS..Hα-helixtrans-45.5-52.7-175.3-176.669.151.600112.7T99 A103 I104 D105 S129 C133 L151 V369T99-Q101 PolarHBondContact O-N 3.05Å; T99-Q101 VanDerWaalsContact O-N 3.11Å; Q101-A103 PolarHBondContact O-N 3.26Å; Q101-I104 PolarHBondContact O-N 2.97Å; Q101-D105 PolarHBondContact NE2-OD1 3.01Å; Q101-D105 PolarHBondContact NE2-OD2 3.39Å; Q101-D105 WeakPolarHBondContact O-CB 3.45Å; Q101-D105 PolarHBondContact O-N 3.33Å; Q101-S129 PolarHBondContact NE2-O 3.02Å; Q101-S129 PolarHBondContact NE2-OG 3.14Å; Q101-S129 VanDerWaalsContact NE2-OG 3.16Å; Q101-C133 VanDerWaalsContact OE1-CB 3.27Å; Q101-C133 VanDerWaalsContact OE1-N 3.08Å; Q101-L151 HydrophobicContact CB-CD1 4.08Å; Q101-L151 HydrophobicContact CB-CD2 3.99Å; Q101-L151 HydrophobicContact CG-CD1 4Å; Q101-V369 HydrophobicContact CG-CB 4.49Å; Q101-V369 HydrophobicContact CG-CG1 4.46Å
102A98.4Very high97.2Very high51 Ų5147.6 Ų47.642%0.42127%0.266SS..Hα-helixtrans-64.7-36.1-17800000113.4Q100 T106 T370Q100-A102 VanDerWaalsContact C-N 3.32Å; Q100-A102 PolarHBondContact O-N 3.35Å; A102-T106 WeakPolarHBondContact O-CB 3.29Å; A102-T106 PolarHBondContact O-N 2.83Å; A102-T106 PolarHBondContact O-OG1 2.83Å; A102-T370 WeakPolarHBondContact CA-OG1 3.41Å; A102-T370 HydrophobicContact CB-CG2 4.04Å
103A98.5Very high97.4Very high40 Ų4044.2 Ų44.233%0.33127%0.27SS..Hα-helixtrans-71.3-40.6178.400000111.3F96 Q100 Q101 F107F96-A103 HydrophobicContact CD1-CB 4.47Å; F96-A103 HydrophobicContact CE1-CB 4.15Å; Q100-A103 HydrophobicContact CB-CB 4.08Å; Q100-A103 PolarHBondContact O-N 2.93Å; Q101-A103 PolarHBondContact O-N 3.26Å; A103-F107 VanDerWaalsContact O-CB 3.26Å; A103-F107 WeakPolarHBondContact O-CB 3.17Å; A103-F107 PolarHBondContact O-N 2.77Å
104I98.7Very high97.5Very high0 Ų042.3 Ų42.30%025%0.254CS..Hα-helixtrans-64.4-49.5176.4-70.2164.7000110.6I17 L91 F96 E97 Q100 Q101 T106 F107 M108 V132I17-I104 HydrophobicContact CD1-CD1 4.26Å; L91-I104 HydrophobicContact CD1-CG2 4.23Å; L91-I104 HydrophobicContact CD2-CG2 3.87Å; F96-I104 HydrophobicContact CB-CD1 3.9Å; F96-I104 HydrophobicContact CB-CG1 3.61Å; F96-I104 HydrophobicContact CD2-CG1 3.86Å; F96-I104 HydrophobicContact CG-CG1 3.8Å; E97-I104 WeakPolarHBondContact O-CD1 3.3Å; Q100-I104 PolarHBondContact O-N 3.37Å; Q101-I104 PolarHBondContact O-N 2.97Å; I104-T106 PolarHBondContact O-N 3.35Å; I104-F107 PolarHBondContact O-N 2.83Å; I104-M108 HydrophobicContact CG2-CE 3.99Å; I104-M108 WeakPolarHBondContact O-CG 3.45Å; I104-M108 PolarHBondContact O-N 3.01Å; I104-V132 HydrophobicContact CD1-CG1 3.63Å; I104-V132 HydrophobicContact CD1-CG2 4.37Å; I104-V132 HydrophobicContact CG2-CG1 4.49Å; I104-V132 HydrophobicContact CG2-CG2 4.07Å
105D98.7Very high97.5Very high0 Ų043.7 Ų43.70%026%0.263CS..Hα-helixtrans-60.4-48.3177.7-71.9-19.2000110.7Q101 F107 M108 L109 S129 T370Q101-D105 PolarHBondContact NE2-OD1 3.01Å; Q101-D105 PolarHBondContact NE2-OD2 3.39Å; Q101-D105 WeakPolarHBondContact O-CB 3.45Å; Q101-D105 PolarHBondContact O-N 3.33Å; D105-F107 VanDerWaalsContact C-N 3.28Å; D105-F107 PolarHBondContact O-N 2.71Å; D105-M108 PolarHBondContact O-N 2.89Å; D105-M108 VanDerWaalsContact O-N 3.15Å; D105-M108 WeakPolarHBondContact OD1-CE 3.33Å; D105-L109 VanDerWaalsContact O-CG 3.3Å; D105-L109 WeakPolarHBondContact O-CG 3.1Å; D105-L109 PolarHBondContact O-N 3.13Å; D105-S129 VanDerWaalsContact CG-OG 3.22Å; D105-S129 WeakPolarHBondContact OD1-CB 3.43Å; D105-S129 PolarHBondContact OD1-OG 3.38Å; D105-S129 PolarHBondContact OD2-OG 3.5Å; D105-T370 WeakPolarHBondContact OD2-CB 3.1Å; D105-T370 PolarHBondContact OD2-N 2.98Å; D105-T370 PolarHBondContact OD2-OG1 3.23Å
106T98.5Very high97.6Very high61 Ų6144.7 Ų44.737%0.37426%0.256SS..Hα-helixtrans-58.1-41177-60.60000111.9A102 I104 L109 Q110A102-T106 WeakPolarHBondContact O-CB 3.29Å; A102-T106 PolarHBondContact O-N 2.83Å; A102-T106 PolarHBondContact O-OG1 2.83Å; I104-T106 PolarHBondContact O-N 3.35Å; T106-L109 PolarHBondContact O-N 2.87Å; T106-Q110 VanDerWaalsContact O-CG 3.29Å; T106-Q110 WeakPolarHBondContact O-CG 3.49Å; T106-Q110 PolarHBondContact O-N 2.73Å
107F98.6Very high97.7Very high30 Ų3043.1 Ų43.113%0.13225%0.249CC..Hα-helixtrans-65.5-42.1177.3175.8-105.3000112.2A90 L91 K94 F96 A103 I104 D105 L109 Q110 L111A90-F107 HydrophobicContact CB-CE1 3.78Å; A90-F107 HydrophobicContact CB-CZ 3.93Å; L91-F107 HydrophobicContact CD2-CD1 3.58Å; L91-F107 HydrophobicContact CD2-CE1 4.02Å; L91-F107 HydrophobicContact CG-CD1 4.48Å; K94-F107 HydrophobicContact CD-CE2 4.16Å; K94-F107 HydrophobicContact CD-CZ 4.34Å; K94-F107 HydrophobicContact CG-CD1 4.46Å; K94-F107 HydrophobicContact CG-CD2 4.36Å; K94-F107 HydrophobicContact CG-CE1 3.98Å; K94-F107 HydrophobicContact CG-CE2 3.91Å; K94-F107 HydrophobicContact CG-CZ 3.67Å; F96-F107 HydrophobicContact CE2-CB 3.81Å; F96-F107 AromaticContact CE2-CD1 3.88Å; F96-F107 HydrophobicContact CE2-CD1 3.88Å; F96-F107 HydrophobicContact CE2-CD2 4.4Å; F96-F107 AromaticContact CE2-CG 3.76Å; F96-F107 HydrophobicContact CE2-CG 3.76Å; F96-F107 HydrophobicContact CZ-CB 4.07Å; F96-F107 HydrophobicContact CZ-CG 4.24Å; A103-F107 VanDerWaalsContact O-CB 3.26Å; A103-F107 WeakPolarHBondContact O-CB 3.17Å; A103-F107 PolarHBondContact O-N 2.77Å; I104-F107 PolarHBondContact O-N 2.83Å; D105-F107 VanDerWaalsContact C-N 3.28Å; D105-F107 PolarHBondContact O-N 2.71Å; F107-L109 VanDerWaalsContact C-N 3.34Å; F107-L109 PolarHBondContact O-N 2.77Å; F107-Q110 PolarHBondContact O-N 3.43Å; F107-L111 WeakPolarHBondContact O-CB 3.36Å; F107-L111 PolarHBondContact O-N 3.42Å
108M98.7Very high97.8Very high0 Ų044.1 Ų44.10%026%0.259CS..Hα-helixtrans-63.7-39.3175.5-69.3-171.5-66.400112I87 L91 I104 D105 L111 D112 I125 V128I87-M108 HydrophobicContact CG2-CG 4.15Å; I87-M108 HydrophobicContact CG2-SD 3.81Å; L91-M108 HydrophobicContact CD1-CG 4.49Å; L91-M108 HydrophobicContact CD1-SD 4.22Å; L91-M108 HydrophobicContact CD2-CG 4.46Å; I104-M108 HydrophobicContact CG2-CE 3.99Å; I104-M108 WeakPolarHBondContact O-CG 3.45Å; I104-M108 PolarHBondContact O-N 3.01Å; D105-M108 PolarHBondContact O-N 2.89Å; D105-M108 VanDerWaalsContact O-N 3.15Å; D105-M108 WeakPolarHBondContact OD1-CE 3.33Å; M108-L111 PolarHBondContact O-N 3Å; M108-D112 PolarHBondContact O-N 2.92Å; M108-I125 HydrophobicContact CB-CG1 4.45Å; M108-I125 HydrophobicContact CB-CG2 4.12Å; M108-I125 HydrophobicContact CE-CG2 4Å; M108-I125 HydrophobicContact SD-CG2 4.4Å; M108-V128 HydrophobicContact CE-CB 4.34Å; M108-V128 HydrophobicContact CE-CG1 4.2Å; M108-V128 HydrophobicContact SD-CB 3.8Å; M108-V128 HydrophobicContact SD-CG1 3.63Å
109L98.4Very high97.9Very high48 Ų4849.8 Ų49.825%0.25128%0.283SS..Hα-helixtrans-62.1-42.4174.1-66.1173.8000112D105 T106 F107 L111 D112 G113 K117 I125 E371D105-L109 VanDerWaalsContact O-CG 3.3Å; D105-L109 WeakPolarHBondContact O-CG 3.1Å; D105-L109 PolarHBondContact O-N 3.13Å; T106-L109 PolarHBondContact O-N 2.87Å; F107-L109 VanDerWaalsContact C-N 3.34Å; F107-L109 PolarHBondContact O-N 2.77Å; L109-L111 VanDerWaalsContact C-N 3.34Å; L109-D112 PolarHBondContact O-N 2.99Å; L109-G113 PolarHBondContact O-N 2.81Å; L109-K117 HydrophobicContact CD2-CD 4.32Å; L109-K117 HydrophobicContact CD2-CG 4.29Å; L109-I125 HydrophobicContact CD2-CD1 4.5Å; L109-E371 HydrophobicContact CD1-CG 4.16Å
110Q98.4Very high97.9Very high139 Ų13948.1 Ų48.165%0.6527%0.273SS*.Hα-helixtrans-66.2-35.8175.3-72170.5-2.800112.4T106 F107 G113T106-Q110 VanDerWaalsContact O-CG 3.29Å; T106-Q110 WeakPolarHBondContact O-CG 3.49Å; T106-Q110 PolarHBondContact O-N 2.73Å; F107-Q110 PolarHBondContact O-N 3.43Å; Q110-G113 PolarHBondContact O-N 3.48Å
111L98.3Very high98Very high41 Ų4144 Ų4422%0.21525%0.254CS..Hα-helixtrans-67.7-36.9177.9-173.362.2000112.2V86 I87 A90 F107 M108 L109 K119 L120V86-L111 HydrophobicContact CG1-CD2 4.11Å; V86-L111 HydrophobicContact CG1-CG 4.37Å; I87-L111 HydrophobicContact CG1-CD2 4.41Å; A90-L111 HydrophobicContact CB-CD2 3.79Å; F107-L111 WeakPolarHBondContact O-CB 3.36Å; F107-L111 PolarHBondContact O-N 3.42Å; M108-L111 PolarHBondContact O-N 3Å; L109-L111 VanDerWaalsContact C-N 3.34Å; L111-K119 PolarHBondContact O-NZ 3.05Å; L111-L120 HydrophobicContact CB-CD1 4.15Å; L111-L120 HydrophobicContact CD2-CD1 4.19Å; L111-L120 HydrophobicContact CG-CD1 4.03Å
112D98.6Very high97.9Very high3 Ų344 Ų442%0.01625%0.254CS..Hα-helixtrans-66.1-55.8168.7-167.5-60.1000110.7M108 L109 T114 K117 K119 L120 I125M108-D112 PolarHBondContact O-N 2.92Å; L109-D112 PolarHBondContact O-N 2.99Å; D112-T114 PolarHBondContact O-N 3.5Å; D112-T114 VanDerWaalsContact OD1-CB 3.31Å; D112-T114 WeakPolarHBondContact OD1-CB 3.4Å; D112-T114 WeakPolarHBondContact OD1-CG2 3.48Å; D112-T114 PolarHBondContact OD1-N 2.59Å; D112-T114 VanDerWaalsContact OD1-N 3.13Å; D112-T114 PolarHBondContact OD1-OG1 3.28Å; D112-K117 WeakPolarHBondContact OD2-CA 3.31Å; D112-K119 WeakPolarHBondContact O-CD 3.42Å; D112-K119 WeakPolarHBondContact OD1-CB 3.22Å; D112-K119 PolarHBondContact OD1-N 3.39Å; D112-K119 PolarHBondContact OD2-N 2.85Å; D112-L120 HydrophobicContact CB-CB 4.37Å; D112-L120 HydrophobicContact CB-CD1 3.91Å; D112-L120 HydrophobicContact CB-CG 3.98Å; D112-L120 WeakPolarHBondContact OD2-CB 3.36Å; D112-L120 PolarHBondContact OD2-N 3.16Å; D112-I125 HydrophobicContact CB-CD1 4.16Å
113G97.7Very high97.9Very high64 Ų6441.5 Ų41.566%0.6623%0.234SC*.  trans72.96.4176.500000114.9L109 Q110L109-G113 PolarHBondContact O-N 2.81Å; Q110-G113 PolarHBondContact O-N 3.48Å
114T98Very high98Very high54 Ų5439.6 Ų39.633%0.33122%0.218SC..SBendtrans-109158.4174.275.40000111.5D112 K117 S118 K119D112-T114 PolarHBondContact O-N 3.5Å; D112-T114 VanDerWaalsContact OD1-CB 3.31Å; D112-T114 WeakPolarHBondContact OD1-CB 3.4Å; D112-T114 WeakPolarHBondContact OD1-CG2 3.48Å; D112-T114 PolarHBondContact OD1-N 2.59Å; D112-T114 VanDerWaalsContact OD1-N 3.13Å; D112-T114 PolarHBondContact OD1-OG1 3.28Å; T114-K117 WeakPolarHBondContact OG1-CA 3.46Å; T114-K117 PolarHBondContact OG1-N 3.25Å; T114-S118 PolarHBondContact OG1-N 3.44Å; T114-S118 PolarHBondContact OG1-OG 3.03Å; T114-K119 HydrophobicContact CG2-CB 4.06Å
115E94.1Very high98Very high150 Ų15039.6 Ų39.670%0.70122%0.218SC*.THydrogen-bonded Turntrans-66.9-40.6-177.8179.7166.4-150.200113.1K345E115-K345 IonicContact OE1-NZ 2.72Å; E115-K345 PolarHBondContact OE1-NZ 3.2Å
116N95Very high98Very high70 Ų7039.6 Ų39.637%0.37422%0.218SC..THydrogen-bonded Turntrans-104.518.6-174.470-22.5000113.5L61 S118L61-N116 PolarHBondContact N-O 3.32Å; N116-S118 VanDerWaalsContact C-N 3.25Å; N116-S118 PolarHBondContact O-N 3.5Å; N116-S118 WeakPolarHBondContact OD1-CB 3.45Å; N116-S118 PolarHBondContact OD1-N 3.01Å; N116-S118 PolarHBondContact OD1-OG 2.93Å
117K97.6Very high98Very high5 Ų536.7 Ų36.72%0.02220%0.2CC..  trans60.433.8179.7-53.5169.2170.268.10113A60 L109 D112 T114 G121 A122 I125 I366 E371A60-K117 HydrophobicContact CB-CD 4.06Å; L109-K117 HydrophobicContact CD2-CD 4.32Å; L109-K117 HydrophobicContact CD2-CG 4.29Å; D112-K117 WeakPolarHBondContact OD2-CA 3.31Å; T114-K117 WeakPolarHBondContact OG1-CA 3.46Å; T114-K117 PolarHBondContact OG1-N 3.25Å; K117-G121 CarbonylContact O-C 3.54Å; K117-G121 WeakPolarHBondContact O-CA 3.24Å; K117-G121 PolarHBondContact O-N 3.44Å; K117-A122 HydrophobicContact CB-CB 4.27Å; K117-A122 HydrophobicContact CD-CB 4.02Å; K117-I125 HydrophobicContact CB-CD1 4.02Å; K117-I125 HydrophobicContact CD-CD1 4.02Å; K117-I125 HydrophobicContact CG-CD1 3.89Å; K117-I366 WeakPolarHBondContact CD-O 3.47Å; K117-I366 WeakPolarHBondContact CE-O 3.38Å; K117-I366 PolarHBondContact NZ-O 3.07Å; K117-E371 WeakPolarHBondContact CE-OE2 3.47Å; K117-E371 VanDerWaalsContact NZ-CD 3.26Å; K117-E371 IonicContact NZ-OE1 3.73Å; K117-E371 PolarHBondContact NZ-OE1 2.79Å; K117-E371 IonicContact NZ-OE2 2.77Å; K117-E371 PolarHBondContact NZ-OE2 2.92Å
118S97.2Very high98Very high45 Ų4535.3 Ų35.332%0.31519%0.194SC..THydrogen-bonded Turntrans-78.1-15.1-173.750.80000114.8M63 T114 N116M63-S118 VanDerWaalsContact CE-O 3.25Å; M63-S118 WeakPolarHBondContact CE-O 3.43Å; T114-S118 PolarHBondContact OG1-N 3.44Å; T114-S118 PolarHBondContact OG1-OG 3.03Å; N116-S118 VanDerWaalsContact C-N 3.25Å; N116-S118 PolarHBondContact O-N 3.5Å; N116-S118 WeakPolarHBondContact OD1-CB 3.45Å; N116-S118 PolarHBondContact OD1-N 3.01Å; N116-S118 PolarHBondContact OD1-OG 2.93Å
119K98.4Very high98Very high119 Ų11935.3 Ų35.352%0.51719%0.194SC..THydrogen-bonded Turntrans-82.8-43.8179-175.1-169.7175-1690112.2M63 N82 L111 D112 T114M63-K119 WeakPolarHBondContact CE-O 3.27Å; N82-K119 PolarHBondContact ND2-O 3.45Å; L111-K119 PolarHBondContact O-NZ 3.05Å; D112-K119 WeakPolarHBondContact O-CD 3.42Å; D112-K119 WeakPolarHBondContact OD1-CB 3.22Å; D112-K119 PolarHBondContact OD1-N 3.39Å; D112-K119 PolarHBondContact OD2-N 2.85Å; T114-K119 HydrophobicContact CG2-CB 4.06Å
120L98.6Very high98Very high3 Ų333.1 Ų33.12%0.01618%0.182CC..THydrogen-bonded Turntrans-99-32.2-179.7-61.7179.7000112.1N82 V86 I87 L111 D112 A124 I125N82-L120 HydrophobicContact CB-CD2 4.28Å; N82-L120 WeakPolarHBondContact ND2-CA 3.32Å; N82-L120 PolarHBondContact ND2-O 2.93Å; V86-L120 HydrophobicContact CB-CD2 4.36Å; V86-L120 HydrophobicContact CG1-CD2 4.01Å; I87-L120 HydrophobicContact CD1-CD1 4.14Å; I87-L120 HydrophobicContact CG1-CD1 3.99Å; L111-L120 HydrophobicContact CB-CD1 4.15Å; L111-L120 HydrophobicContact CD2-CD1 4.19Å; L111-L120 HydrophobicContact CG-CD1 4.03Å; D112-L120 HydrophobicContact CB-CB 4.37Å; D112-L120 HydrophobicContact CB-CD1 3.91Å; D112-L120 HydrophobicContact CB-CG 3.98Å; D112-L120 WeakPolarHBondContact OD2-CB 3.36Å; D112-L120 PolarHBondContact OD2-N 3.16Å; L120-A124 VanDerWaalsContact O-CB 3.25Å; L120-A124 WeakPolarHBondContact O-CB 3.49Å; L120-I125 HydrophobicContact CB-CD1 4.44Å; L120-I125 HydrophobicContact CB-CG1 4.34Å
121G98.4Very high98.1Very high0 Ų026.5 Ų26.50%015%0.152CC..  trans99132-173.700000111.5K117 N123 A124 I125K117-G121 CarbonylContact O-C 3.54Å; K117-G121 WeakPolarHBondContact O-CA 3.24Å; K117-G121 PolarHBondContact O-N 3.44Å; G121-N123 PolarHBondContact O-N 3.01Å; G121-A124 WeakPolarHBondContact O-CB 3.43Å; G121-A124 PolarHBondContact O-N 3.44Å; G121-I125 PolarHBondContact O-N 3.15Å; G121-I125 VanDerWaalsContact O-N 3.1Å
122A98.3Very high98.1Very high0 Ų024.6 Ų24.60%014%0.141CC..Hα-helixtrans-58.9-38.3175.600000111.9A60 L61 K117 A124 I125 L126A60-A122 HydrophobicContact CB-CB 3.52Å; L61-A122 VanDerWaalsContact O-CB 3.3Å; L61-A122 WeakPolarHBondContact O-CB 3.34Å; L61-A122 PolarHBondContact O-N 3.26Å; K117-A122 HydrophobicContact CB-CB 4.27Å; K117-A122 HydrophobicContact CD-CB 4.02Å; A122-A124 VanDerWaalsContact C-N 3.31Å; A122-A124 PolarHBondContact O-N 2.88Å; A122-I125 PolarHBondContact O-N 2.61Å; A122-L126 WeakPolarHBondContact O-CB 3.41Å; A122-L126 PolarHBondContact O-N 2.87Å
123N98.4Very high98.1Very high0 Ų024.4 Ų24.40%014%0.141CC..Hα-helixtrans-66.1-29174.156.5-27.2000113.5V34 V49 E62 M63 G121 G127V34-N123 HydrophobicContact CG2-CB 4.4Å; V49-N123 HydrophobicContact CG1-CB 3.91Å; E62-N123 HydrophobicContact CG-CB 4.25Å; M63-N123 PolarHBondContact N-OD1 2.98Å; M63-N123 PolarHBondContact O-ND2 2.96Å; M63-N123 VanDerWaalsContact O-ND2 3.08Å; G121-N123 PolarHBondContact O-N 3.01Å; N123-G127 PolarHBondContact O-N 3.38Å
124A98.8Very high98.1Very high0 Ų023.2 Ų23.20%012%0.117CC..Hα-helixtrans-70.8-50.5173.100000111.5A79 I83 I87 L120 G121 A122 V128A79-A124 HydrophobicContact CB-CB 4.33Å; I83-A124 HydrophobicContact CD1-CB 3.99Å; I83-A124 HydrophobicContact CG1-CB 3.65Å; I87-A124 HydrophobicContact CD1-CB 4.16Å; L120-A124 VanDerWaalsContact O-CB 3.25Å; L120-A124 WeakPolarHBondContact O-CB 3.49Å; G121-A124 WeakPolarHBondContact O-CB 3.43Å; G121-A124 PolarHBondContact O-N 3.44Å; A122-A124 VanDerWaalsContact C-N 3.31Å; A122-A124 PolarHBondContact O-N 2.88Å; A124-V128 PolarHBondContact O-N 2.67Å
125I98.8Very high98.2Very high0 Ų020.6 Ų20.60%010%0.101CC..Hα-helixtrans-63.4-45.5-179.3-63.2177.8000110.5M108 L109 D112 K117 L120 G121 A122 G127 V128 S129 G367M108-I125 HydrophobicContact CB-CG1 4.45Å; M108-I125 HydrophobicContact CB-CG2 4.12Å; M108-I125 HydrophobicContact CE-CG2 4Å; M108-I125 HydrophobicContact SD-CG2 4.4Å; L109-I125 HydrophobicContact CD2-CD1 4.5Å; D112-I125 HydrophobicContact CB-CD1 4.16Å; K117-I125 HydrophobicContact CB-CD1 4.02Å; K117-I125 HydrophobicContact CD-CD1 4.02Å; K117-I125 HydrophobicContact CG-CD1 3.89Å; L120-I125 HydrophobicContact CB-CD1 4.44Å; L120-I125 HydrophobicContact CB-CG1 4.34Å; G121-I125 PolarHBondContact O-N 3.15Å; G121-I125 VanDerWaalsContact O-N 3.1Å; A122-I125 PolarHBondContact O-N 2.61Å; I125-G127 PolarHBondContact O-N 2.88Å; I125-V128 PolarHBondContact O-N 3.44Å; I125-S129 VanDerWaalsContact O-CB 3.31Å; I125-S129 WeakPolarHBondContact O-CB 3.47Å; I125-S129 PolarHBondContact O-N 3.32Å; I125-G367 CarbonylContact C-O 3.58Å; I125-G367 WeakPolarHBondContact CG2-O 3.08Å
126L98.8Very high98.4Very high0 Ų013.5 Ų13.50%07%0.068CC..Hα-helixtrans-62.4-47.5-178.4179.860.9000111.6V49 A122 V128 S129 L130 V363 N364 G367V49-L126 HydrophobicContact CG1-CD2 3.87Å; V49-L126 HydrophobicContact CG2-CB 4.44Å; V49-L126 HydrophobicContact CG2-CG 4.36Å; A122-L126 WeakPolarHBondContact O-CB 3.41Å; A122-L126 PolarHBondContact O-N 2.87Å; L126-V128 VanDerWaalsContact C-N 3.25Å; L126-V128 PolarHBondContact O-N 3.44Å; L126-S129 WeakPolarHBondContact O-CB 3.49Å; L126-S129 PolarHBondContact O-N 2.9Å; L126-S129 VanDerWaalsContact O-N 3.07Å; L126-L130 HydrophobicContact CD1-CD1 3.98Å; L126-L130 HydrophobicContact CD1-CD2 3.85Å; L126-L130 HydrophobicContact CD1-CG 3.67Å; L126-L130 HydrophobicContact CD2-CD1 4.44Å; L126-L130 HydrophobicContact CG-CD1 3.87Å; L126-L130 HydrophobicContact CG-CG 4.01Å; L126-L130 VanDerWaalsContact O-CG 3.27Å; L126-L130 WeakPolarHBondContact O-CG 3.45Å; L126-L130 PolarHBondContact O-N 3.42Å; L126-V363 HydrophobicContact CD1-CB 4.03Å; L126-V363 HydrophobicContact CD1-CG2 4.3Å; L126-V363 HydrophobicContact CD2-CB 4.33Å; L126-V363 HydrophobicContact CD2-CG2 4Å; L126-N364 HydrophobicContact CD2-CB 4Å; L126-G367 WeakPolarHBondContact CA-O 3.44Å; L126-G367 WeakPolarHBondContact CB-O 3.21Å; L126-G367 PolarHBondContact N-O 2.92Å; L126-G367 VanDerWaalsContact N-O 3.12Å
127G98.8Very high98.5Very high0 Ų010.3 Ų10.30%05%0.051CC..Hα-helixtrans-55.5-42.7-179.100000112.3V49 N123 I125 A131V49-G127 VanDerWaalsContact CG2-CA 3.43Å; N123-G127 PolarHBondContact O-N 3.38Å; I125-G127 PolarHBondContact O-N 2.88Å; G127-A131 WeakPolarHBondContact O-CB 3.48Å; G127-A131 PolarHBondContact O-N 3.1Å
128V98.9Very high98.5Very high0 Ų012.4 Ų12.40%07%0.065CC..Hα-helixtrans-68.6-46.6175179.60000111.2L20 V36 I83 I87 L91 M108 A124 I125 L126 L130 A131 V132L20-V128 HydrophobicContact CD1-CG1 4.09Å; L20-V128 HydrophobicContact CD2-CG1 4.26Å; V36-V128 HydrophobicContact CG1-CG2 4.16Å; V36-V128 HydrophobicContact CG2-CG2 4.38Å; I83-V128 HydrophobicContact CG1-CG2 4.19Å; I83-V128 HydrophobicContact CG2-CG2 3.76Å; I87-V128 HydrophobicContact CG2-CG1 4.31Å; I87-V128 HydrophobicContact CG2-CG2 4.11Å; L91-V128 HydrophobicContact CD1-CG1 3.71Å; M108-V128 HydrophobicContact CE-CB 4.34Å; M108-V128 HydrophobicContact CE-CG1 4.2Å; M108-V128 HydrophobicContact SD-CB 3.8Å; M108-V128 HydrophobicContact SD-CG1 3.63Å; A124-V128 PolarHBondContact O-N 2.67Å; I125-V128 PolarHBondContact O-N 3.44Å; L126-V128 VanDerWaalsContact C-N 3.25Å; L126-V128 PolarHBondContact O-N 3.44Å; V128-L130 VanDerWaalsContact C-N 3.33Å; V128-L130 PolarHBondContact O-N 2.85Å; V128-A131 PolarHBondContact O-N 3.44Å; V128-V132 HydrophobicContact CG1-CG2 4.18Å; V128-V132 VanDerWaalsContact O-CG2 3.26Å; V128-V132 WeakPolarHBondContact O-CG2 3.34Å; V128-V132 PolarHBondContact O-N 2.88Å
129S98.9Very high98.5Very high0 Ų011.3 Ų11.30%05%0.054CC..Hα-helixtrans-56.4-43.7-179.8-170.80000112.7Q101 D105 I125 L126 V132 C133 V369Q101-S129 PolarHBondContact NE2-O 3.02Å; Q101-S129 PolarHBondContact NE2-OG 3.14Å; Q101-S129 VanDerWaalsContact NE2-OG 3.16Å; D105-S129 VanDerWaalsContact CG-OG 3.22Å; D105-S129 WeakPolarHBondContact OD1-CB 3.43Å; D105-S129 PolarHBondContact OD1-OG 3.38Å; D105-S129 PolarHBondContact OD2-OG 3.5Å; I125-S129 VanDerWaalsContact O-CB 3.31Å; I125-S129 WeakPolarHBondContact O-CB 3.47Å; I125-S129 PolarHBondContact O-N 3.32Å; L126-S129 WeakPolarHBondContact O-CB 3.49Å; L126-S129 PolarHBondContact O-N 2.9Å; L126-S129 VanDerWaalsContact O-N 3.07Å; S129-V132 PolarHBondContact O-N 3.07Å; S129-C133 PolarHBondContact O-N 3.28Å; S129-V369 PolarHBondContact OG-N 3.39Å
130L98.9Very high98.4Very high3 Ų310.2 Ų10.22%0.0165%0.049CC..Hα-helixtrans-65.7-44176.6-64.4179.7000111.9A47 L126 V128 V132 C133 K134 V369 F399A47-L130 HydrophobicContact CB-CB 3.45Å; A47-L130 VanDerWaalsContact CB-CB 3.45Å; A47-L130 HydrophobicContact CB-CD1 4.39Å; L126-L130 HydrophobicContact CD1-CD1 3.98Å; L126-L130 HydrophobicContact CD1-CD2 3.85Å; L126-L130 HydrophobicContact CD1-CG 3.67Å; L126-L130 HydrophobicContact CD2-CD1 4.44Å; L126-L130 HydrophobicContact CG-CD1 3.87Å; L126-L130 HydrophobicContact CG-CG 4.01Å; L126-L130 VanDerWaalsContact O-CG 3.27Å; L126-L130 WeakPolarHBondContact O-CG 3.45Å; L126-L130 PolarHBondContact O-N 3.42Å; V128-L130 VanDerWaalsContact C-N 3.33Å; V128-L130 PolarHBondContact O-N 2.85Å; L130-V132 VanDerWaalsContact C-N 3.35Å; L130-C133 PolarHBondContact O-N 3.14Å; L130-K134 WeakPolarHBondContact O-CG 3.25Å; L130-K134 PolarHBondContact O-N 2.88Å; L130-V369 HydrophobicContact CD2-CG2 3.77Å; L130-F399 HydrophobicContact CB-CD2 4.45Å; L130-F399 HydrophobicContact CD2-CD1 3.42Å; L130-F399 VanDerWaalsContact CD2-CD1 3.42Å; L130-F399 HydrophobicContact CD2-CD2 3.78Å; L130-F399 HydrophobicContact CD2-CE1 3.35Å; L130-F399 HydrophobicContact CD2-CE2 3.72Å; L130-F399 HydrophobicContact CD2-CG 3.64Å; L130-F399 HydrophobicContact CD2-CZ 3.52Å
131A98.8Very high98.3Very high0 Ų016 Ų160%08%0.081CC..Hα-helixtrans-65.1-38.6178.700000111.9V36 L38 A47 G127 V128 K134 A135V36-A131 HydrophobicContact CG1-CB 4.28Å; L38-A131 HydrophobicContact CB-CB 3.77Å; L38-A131 HydrophobicContact CD1-CB 4.34Å; A47-A131 HydrophobicContact CB-CB 4.06Å; G127-A131 WeakPolarHBondContact O-CB 3.48Å; G127-A131 PolarHBondContact O-N 3.1Å; V128-A131 PolarHBondContact O-N 3.44Å; A131-K134 PolarHBondContact O-N 3.02Å; A131-A135 WeakPolarHBondContact O-CB 3.48Å; A131-A135 PolarHBondContact O-N 2.96Å
132V98.7Very high98.3Very high0 Ų018.8 Ų18.80%010%0.098CC..Hα-helixtrans-60.1-47.1172.3172.30000110.5I17 L38 V98 I104 V128 S129 L130 K134 A135 G136I17-V132 HydrophobicContact CD1-CG2 4.31Å; L38-V132 HydrophobicContact CD1-CB 4.17Å; L38-V132 HydrophobicContact CD1-CG2 3.46Å; L38-V132 VanDerWaalsContact CD1-CG2 3.46Å; V98-V132 WeakPolarHBondContact O-CG1 3.21Å; I104-V132 HydrophobicContact CD1-CG1 3.63Å; I104-V132 HydrophobicContact CD1-CG2 4.37Å; I104-V132 HydrophobicContact CG2-CG1 4.49Å; I104-V132 HydrophobicContact CG2-CG2 4.07Å; V128-V132 HydrophobicContact CG1-CG2 4.18Å; V128-V132 VanDerWaalsContact O-CG2 3.26Å; V128-V132 WeakPolarHBondContact O-CG2 3.34Å; V128-V132 PolarHBondContact O-N 2.88Å; S129-V132 PolarHBondContact O-N 3.07Å; L130-V132 VanDerWaalsContact C-N 3.35Å; V132-K134 VanDerWaalsContact C-N 3.32Å; V132-K134 PolarHBondContact O-N 3.26Å; V132-A135 WeakPolarHBondContact O-CB 3.25Å; V132-A135 PolarHBondContact O-N 3.29Å; V132-A135 VanDerWaalsContact O-N 3.13Å; V132-G136 PolarHBondContact O-N 3.44Å
133C98.8Very high98.3Very high0 Ų020.6 Ų20.60%011%0.11CC..Hα-helixtrans-61.6-41.3-180-171.40000112Q101 S129 L130 G136 A137 Y147 V369 F399Q101-C133 VanDerWaalsContact OE1-CB 3.27Å; Q101-C133 VanDerWaalsContact OE1-N 3.08Å; S129-C133 PolarHBondContact O-N 3.28Å; L130-C133 PolarHBondContact O-N 3.14Å; C133-G136 PolarHBondContact O-N 2.82Å; C133-A137 PolarHBondContact O-N 3.24Å; C133-A137 VanDerWaalsContact O-N 3.1Å; C133-Y147 VanDerWaalsContact O-CD1 3.28Å; C133-Y147 WeakPolarHBondContact O-CD1 3.46Å; C133-Y147 WeakPolarHBondContact O-CE1 3.26Å; C133-V369 HydrophobicContact CB-CG2 4.18Å; C133-F399 HydrophobicContact CB-CE2 3.92Å; C133-F399 HydrophobicContact CB-CZ 4.33Å
134K98.8Very high98.3Very high38 Ų3821.8 Ų21.817%0.16512%0.116CC..Hα-helixtrans-61.5-43.7173.8-70.5178.7-175.6-171.80112.1F45 R46 L130 A131 V132 V138 L144 D397F45-K134 HydrophobicContact CB-CB 4.12Å; F45-K134 HydrophobicContact CD1-CB 4.42Å; R46-K134 WeakPolarHBondContact O-CD 3.32Å; R46-K134 WeakPolarHBondContact O-CE 3.5Å; R46-K134 PolarHBondContact O-NZ 3.11Å; L130-K134 WeakPolarHBondContact O-CG 3.25Å; L130-K134 PolarHBondContact O-N 2.88Å; A131-K134 PolarHBondContact O-N 3.02Å; V132-K134 VanDerWaalsContact C-N 3.32Å; V132-K134 PolarHBondContact O-N 3.26Å; K134-V138 PolarHBondContact O-N 3.41Å; K134-L144 HydrophobicContact CG-CD1 4.41Å; K134-L144 HydrophobicContact CG-CD2 3.98Å; K134-D397 IonicContact NZ-OD1 3.71Å; K134-D397 PolarHBondContact NZ-OD1 2.85Å; K134-D397 IonicContact NZ-OD2 3.36Å; K134-D397 PolarHBondContact NZ-OD2 3.19Å
135A98.5Very high98.3Very high0 Ų021.9 Ų21.90%012%0.117CC..Hα-helixtrans-64.7-41.3176.200000112.2M15 L38 T40 F45 V98 A131 V132 A137 V138 H139M15-A135 HydrophobicContact CE-CB 4.23Å; M15-A135 WeakPolarHBondContact CE-O 3.48Å; L38-A135 HydrophobicContact CD1-CB 4.47Å; L38-A135 HydrophobicContact CD2-CB 3.91Å; T40-A135 HydrophobicContact CG2-CB 4.41Å; F45-A135 HydrophobicContact CB-CB 4.2Å; F45-A135 HydrophobicContact CD1-CB 4.22Å; F45-A135 HydrophobicContact CD2-CB 3.39Å; F45-A135 HydrophobicContact CE2-CB 3.77Å; F45-A135 HydrophobicContact CG-CB 3.64Å; F45-A135 HydrophobicContact CZ-CB 4.33Å; V98-A135 HydrophobicContact CB-CB 3.95Å; V98-A135 HydrophobicContact CG1-CB 3.97Å; V98-A135 HydrophobicContact CG2-CB 4Å; A131-A135 WeakPolarHBondContact O-CB 3.48Å; A131-A135 PolarHBondContact O-N 2.96Å; V132-A135 WeakPolarHBondContact O-CB 3.25Å; V132-A135 PolarHBondContact O-N 3.29Å; V132-A135 VanDerWaalsContact O-N 3.13Å; A135-A137 PolarHBondContact O-N 2.79Å; A135-V138 PolarHBondContact O-N 3.17Å; A135-H139 PolarHBondContact O-N 3.24Å
136G98.3Very high98.2Very high0 Ų025 Ų250%013%0.129CC..Hα-helixtrans-60.4-41.4177.600000113V132 C133 H139 K140V132-G136 PolarHBondContact O-N 3.44Å; C133-G136 PolarHBondContact O-N 2.82Å; G136-H139 WeakPolarHBondContact O-CB 3.48Å; G136-H139 PolarHBondContact O-N 2.93Å; G136-K140 WeakPolarHBondContact O-CG 3.19Å; G136-K140 PolarHBondContact O-N 2.8Å
137A98.4Very high98.2Very high3 Ų325.1 Ų25.13%0.02513%0.129CC..Hα-helixtrans-60.5-47.5175.200000111.9C133 A135 K140 N141 V142 L144 Y147C133-A137 PolarHBondContact O-N 3.24Å; C133-A137 VanDerWaalsContact O-N 3.1Å; A135-A137 PolarHBondContact O-N 2.79Å; A137-K140 CarbonylContact O-C 3.52Å; A137-K140 PolarHBondContact O-N 2.89Å; A137-N141 PolarHBondContact O-N 2.96Å; A137-V142 CarbonylContact C-O 3.57Å; A137-V142 PolarHBondContact O-N 3.46Å; A137-V142 VanDerWaalsContact O-N 3.11Å; A137-L144 HydrophobicContact CB-CB 4.31Å; A137-L144 HydrophobicContact CB-CD1 3.97Å; A137-Y147 HydrophobicContact CB-CD1 3.92Å; A137-Y147 HydrophobicContact CB-CG 3.91Å; A137-Y147 VanDerWaalsContact N-CD1 3.34Å
138V97.7Very high98.2Very high50 Ų5025.1 Ų25.130%0.30313%0.129SC..Hα-helixtrans-65.9-41.5177.61710000111.2R42 F45 K134 A135 K140 N141R42-V138 HydrophobicContact CB-CG1 4.34Å; R42-V138 PolarHBondContact NH1-O 3.02Å; R42-V138 PolarHBondContact NH2-O 3.24Å; F45-V138 HydrophobicContact CD1-CG2 4.37Å; F45-V138 HydrophobicContact CE1-CB 3.53Å; F45-V138 HydrophobicContact CE1-CG1 3.86Å; F45-V138 HydrophobicContact CE1-CG2 3.57Å; F45-V138 HydrophobicContact CZ-CB 3.9Å; F45-V138 HydrophobicContact CZ-CG1 3.89Å; F45-V138 HydrophobicContact CZ-CG2 4.41Å; K134-V138 PolarHBondContact O-N 3.41Å; A135-V138 PolarHBondContact O-N 3.17Å; V138-K140 VanDerWaalsContact C-N 3.29Å; V138-K140 PolarHBondContact O-N 2.91Å; V138-N141 WeakPolarHBondContact O-CA 3.24Å; V138-N141 PolarHBondContact O-N 3.14Å
139H96.6Very high98.2Very high22 Ų2225.3 Ų25.310%0.10213%0.13CC..Hα-helixtrans-51.9-49.1173.9-179.685.9000111.8A13 M15 R42 V98 T99 A135 G136 N141A13-H139 PolarHBondContact O-CE1 2.66Å; M15-H139 WeakPolarHBondContact CB-ND1 3.17Å; M15-H139 HydrophobicContact CE-CB 3.58Å; M15-H139 HydrophobicContact SD-CB 4.34Å; R42-H139 PolarHBondContact NH1-O 3.45Å; V98-H139 HydrophobicContact CG2-CB 4.1Å; T99-H139 HydrophobicContact CG2-CB 3.99Å; T99-H139 WeakPolarHBondContact CG2-CD2 3.41Å; A135-H139 PolarHBondContact O-N 3.24Å; G136-H139 WeakPolarHBondContact O-CB 3.48Å; G136-H139 PolarHBondContact O-N 2.93Å; H139-N141 PolarHBondContact O-N 3.34Å
140K96.1Very high98.2Very high95 Ų9530.2 Ų30.241%0.41315%0.154SC..THydrogen-bonded Turntrans-73.4-6.1178.1-69.8-75.7-173.7153.30113.7T99 G136 A137 V138 V142 Y147 E150T99-K140 HydrophobicContact CG2-CD 4.43Å; T99-K140 HydrophobicContact CG2-CG 4.04Å; G136-K140 WeakPolarHBondContact O-CG 3.19Å; G136-K140 PolarHBondContact O-N 2.8Å; A137-K140 CarbonylContact O-C 3.52Å; A137-K140 PolarHBondContact O-N 2.89Å; V138-K140 VanDerWaalsContact C-N 3.29Å; V138-K140 PolarHBondContact O-N 2.91Å; K140-V142 VanDerWaalsContact C-N 3.32Å; K140-V142 HydrophobicContact CB-CG2 3.93Å; K140-V142 PolarHBondContact O-N 3.25Å; K140-Y147 HydrophobicContact CB-CD2 4.49Å; K140-Y147 HydrophobicContact CG-CD2 4.11Å; K140-Y147 HydrophobicContact CG-CE2 4.04Å; K140-E150 IonicContact NZ-OE1 2.82Å; K140-E150 PolarHBondContact NZ-OE1 3.3Å
141N96.7Very high98.2Very high125 Ų12532.6 Ų32.667%0.66817%0.166SC*.THydrogen-bonded Turntrans56.843.8-178.7-160.864.1000112.8R42 A137 V138 H139R42-N141 PolarHBondContact NH2-OD1 3.04Å; A137-N141 PolarHBondContact O-N 2.96Å; V138-N141 WeakPolarHBondContact O-CA 3.24Å; V138-N141 PolarHBondContact O-N 3.14Å; H139-N141 PolarHBondContact O-N 3.34Å
142V97.6Very high98.1Very high59 Ų5933.1 Ų33.136%0.35817%0.17SC..SBendtrans-130.4158177-630000110.2A137 K140 R146A137-V142 CarbonylContact C-O 3.57Å; A137-V142 PolarHBondContact O-N 3.46Å; A137-V142 VanDerWaalsContact O-N 3.11Å; K140-V142 VanDerWaalsContact C-N 3.32Å; K140-V142 HydrophobicContact CB-CG2 3.93Å; K140-V142 PolarHBondContact O-N 3.25Å; V142-R146 HydrophobicContact CB-CB 4.16Å; V142-R146 HydrophobicContact CG2-CB 4.36Å
143S98.1Very high98.1Very high38 Ų3836.1 Ų36.127%0.26620%0.201SC..  trans-59.9150.4172-570000111.2Y145 R146 Y147 E435S143-Y145 PolarHBondContact O-N 3.19Å; S143-R146 WeakPolarHBondContact O-CB 3.14Å; S143-R146 PolarHBondContact O-N 3.34Å; S143-Y147 PolarHBondContact O-N 2.82Å; S143-Y147 VanDerWaalsContact O-N 3.07Å; S143-E435 VanDerWaalsContact OG-CD 3.25Å; S143-E435 PolarHBondContact OG-OE1 3.48Å; S143-E435 VanDerWaalsContact OG-OE1 3.07Å; S143-E435 PolarHBondContact OG-OE2 2.99Å
144L98.8Very high97.9Very high25 Ų2537.7 Ų37.713%0.13121%0.211CC..Hα-helixtrans-58.2-45.3-174.5176.360.6000112.4K134 A137 R146 Y147 I148 F399 D402K134-L144 HydrophobicContact CG-CD1 4.41Å; K134-L144 HydrophobicContact CG-CD2 3.98Å; A137-L144 HydrophobicContact CB-CB 4.31Å; A137-L144 HydrophobicContact CB-CD1 3.97Å; L144-R146 PolarHBondContact O-N 2.97Å; L144-Y147 PolarHBondContact O-N 3.13Å; L144-Y147 VanDerWaalsContact O-N 3.12Å; L144-I148 HydrophobicContact CD1-CD1 4.08Å; L144-I148 HydrophobicContact CD1-CG1 4.22Å; L144-I148 HydrophobicContact CG-CD1 3.94Å; L144-I148 HydrophobicContact CG-CG1 4.5Å; L144-I148 WeakPolarHBondContact O-CG1 3.31Å; L144-I148 PolarHBondContact O-N 3.37Å; L144-F399 HydrophobicContact CD1-CE2 4.42Å; L144-F399 HydrophobicContact CD2-CD2 3.95Å; L144-F399 HydrophobicContact CD2-CE2 4.3Å; L144-D402 HydrophobicContact CB-CB 4.08Å; L144-D402 HydrophobicContact CD2-CB 3.77Å; L144-D402 HydrophobicContact CG-CB 3.75Å
145Y98.6Very high97.7Very high1 Ų144.8 Ų44.80%0.00424%0.242CC..Hα-helixtrans-59.4-32.917674.3-92000113.2S143 A149 V157 D402 V405 G406 I432 E435 L436S143-Y145 PolarHBondContact O-N 3.19Å; Y145-A149 WeakPolarHBondContact O-CB 3.47Å; Y145-A149 PolarHBondContact O-N 2.88Å; Y145-V157 HydrophobicContact CD2-CG1 4.2Å; Y145-V157 HydrophobicContact CD2-CG2 4.38Å; Y145-V157 HydrophobicContact CE2-CG2 4.09Å; Y145-D402 WeakPolarHBondContact CB-O 3.45Å; Y145-D402 PolarHBondContact N-OD1 3.4Å; Y145-V405 HydrophobicContact CD2-CG1 3.64Å; Y145-V405 HydrophobicContact CE2-CG1 4.35Å; Y145-V405 HydrophobicContact CG-CB 4.48Å; Y145-V405 HydrophobicContact CG-CG1 4.02Å; Y145-G406 WeakPolarHBondContact O-CA 3.45Å; Y145-I432 HydrophobicContact CD1-CD1 4.22Å; Y145-I432 HydrophobicContact CD1-CG1 3.96Å; Y145-I432 HydrophobicContact CD1-CG2 3.96Å; Y145-I432 HydrophobicContact CE1-CG1 4.33Å; Y145-I432 HydrophobicContact CE1-CG2 3.98Å; Y145-I432 HydrophobicContact CG-CG2 4.28Å; Y145-E435 WeakPolarHBondContact CE1-OE2 3.48Å; Y145-E435 VanDerWaalsContact OH-CD 3.29Å; Y145-E435 PolarHBondContact OH-OE1 2.58Å; Y145-L436 HydrophobicContact CE2-CD2 4.04Å
146R98.2Very high97.5Very high66 Ų6651.6 Ų51.625%0.24928%0.278CS..Hα-helixtrans-70.8-40175-69.4-61.8-171.5172.50.9111.7V142 S143 L144 A149 E150V142-R146 HydrophobicContact CB-CB 4.16Å; V142-R146 HydrophobicContact CG2-CB 4.36Å; S143-R146 WeakPolarHBondContact O-CB 3.14Å; S143-R146 PolarHBondContact O-N 3.34Å; L144-R146 PolarHBondContact O-N 2.97Å; R146-A149 WeakPolarHBondContact O-CB 3.33Å; R146-A149 PolarHBondContact O-N 3.49Å; R146-E150 PolarHBondContact O-N 2.88Å
147Y98.7Very high97.5Very high2 Ų252.1 Ų52.11%0.00828%0.281CS..Hα-helixtrans-65-41.5175.5-176.5-120.9000111.8T99 C133 A137 K140 S143 L144 A149 E150 L151T99-Y147 WeakPolarHBondContact CA-OH 3.24Å; T99-Y147 PolarHBondContact O-OH 3.23Å; C133-Y147 VanDerWaalsContact O-CD1 3.28Å; C133-Y147 WeakPolarHBondContact O-CD1 3.46Å; C133-Y147 WeakPolarHBondContact O-CE1 3.26Å; A137-Y147 HydrophobicContact CB-CD1 3.92Å; A137-Y147 HydrophobicContact CB-CG 3.91Å; A137-Y147 VanDerWaalsContact N-CD1 3.34Å; K140-Y147 HydrophobicContact CB-CD2 4.49Å; K140-Y147 HydrophobicContact CG-CD2 4.11Å; K140-Y147 HydrophobicContact CG-CE2 4.04Å; S143-Y147 PolarHBondContact O-N 2.82Å; S143-Y147 VanDerWaalsContact O-N 3.07Å; L144-Y147 PolarHBondContact O-N 3.13Å; L144-Y147 VanDerWaalsContact O-N 3.12Å; Y147-A149 VanDerWaalsContact C-N 3.3Å; Y147-A149 PolarHBondContact O-N 2.9Å; Y147-E150 WeakPolarHBondContact O-CB 3.24Å; Y147-E150 PolarHBondContact O-N 3.03Å; Y147-L151 HydrophobicContact CD1-CD1 4.07Å; Y147-L151 HydrophobicContact CE1-CD1 3.66Å; Y147-L151 HydrophobicContact CE1-CG 4.2Å; Y147-L151 HydrophobicContact CE2-CD2 4.34Å; Y147-L151 HydrophobicContact CE2-CG 4.3Å; Y147-L151 WeakPolarHBondContact O-CG 3.43Å; Y147-L151 PolarHBondContact O-N 3.16Å
148I98.8Very high97.4Very high0 Ų052.8 Ų52.80%028%0.284CS..Hα-helixtrans-60.9-41.8172.9-67.7170.8000110.6L144 E150 L151 A152 F399 D402 L403 L407L144-I148 HydrophobicContact CD1-CD1 4.08Å; L144-I148 HydrophobicContact CD1-CG1 4.22Å; L144-I148 HydrophobicContact CG-CD1 3.94Å; L144-I148 HydrophobicContact CG-CG1 4.5Å; L144-I148 WeakPolarHBondContact O-CG1 3.31Å; L144-I148 PolarHBondContact O-N 3.37Å; I148-E150 VanDerWaalsContact C-N 3.35Å; I148-E150 PolarHBondContact O-N 2.85Å; I148-L151 PolarHBondContact O-N 3.39Å; I148-A152 WeakPolarHBondContact O-CB 3.32Å; I148-A152 PolarHBondContact O-N 3.01Å; I148-F399 HydrophobicContact CD1-CE1 4.47Å; I148-F399 HydrophobicContact CD1-CE2 4.18Å; I148-F399 HydrophobicContact CD1-CZ 3.93Å; I148-D402 HydrophobicContact CD1-CB 4.19Å; I148-L403 HydrophobicContact CD1-CB 4.33Å; I148-L403 HydrophobicContact CD1-CD1 4.29Å; I148-L403 HydrophobicContact CG2-CD1 3.9Å; I148-L407 HydrophobicContact CG2-CD2 4.27Å; I148-L407 HydrophobicContact CG2-CG 4.26Å
149A98.3Very high97.5Very high4 Ų450.5 Ų50.53%0.03327%0.27CS..Hα-helixtrans-60.9-41.8175.300000112.2Y145 R146 Y147 A152 G153 V154 V157 G406Y145-A149 WeakPolarHBondContact O-CB 3.47Å; Y145-A149 PolarHBondContact O-N 2.88Å; R146-A149 WeakPolarHBondContact O-CB 3.33Å; R146-A149 PolarHBondContact O-N 3.49Å; Y147-A149 VanDerWaalsContact C-N 3.3Å; Y147-A149 PolarHBondContact O-N 2.9Å; A149-A152 PolarHBondContact O-N 3.29Å; A149-G153 PolarHBondContact O-N 3.47Å; A149-V154 HydrophobicContact CB-CB 4.1Å; A149-V154 HydrophobicContact CB-CG1 4.41Å; A149-V154 PolarHBondContact O-N 2.89Å; A149-V157 HydrophobicContact CB-CG1 3.85Å; A149-G406 VanDerWaalsContact CA-O 3.25Å; A149-G406 WeakPolarHBondContact CA-O 3.33Å; A149-G406 WeakPolarHBondContact CB-O 3.46Å
150E98.3Very high97.6Very high104 Ų10449.4 Ų49.449%0.48627%0.265SS..Hα-helixtrans-58.9-50.9173.1-178.1-178156.400111.1K140 R146 Y147 I148 A152 G153K140-E150 IonicContact NZ-OE1 2.82Å; K140-E150 PolarHBondContact NZ-OE1 3.3Å; R146-E150 PolarHBondContact O-N 2.88Å; Y147-E150 WeakPolarHBondContact O-CB 3.24Å; Y147-E150 PolarHBondContact O-N 3.03Å; I148-E150 VanDerWaalsContact C-N 3.35Å; I148-E150 PolarHBondContact O-N 2.85Å; E150-A152 VanDerWaalsContact C-N 3.26Å; E150-A152 PolarHBondContact O-N 3.04Å; E150-G153 PolarHBondContact O-N 2.88Å
151L98.5Very high97.7Very high53 Ų5344.9 Ų44.928%0.27725%0.246SC..Hα-helixtrans-58.9-36.8178.2-69.1176.1000112.6Q101 Y147 I148 I373Q101-L151 HydrophobicContact CB-CD1 4.08Å; Q101-L151 HydrophobicContact CB-CD2 3.99Å; Q101-L151 HydrophobicContact CG-CD1 4Å; Y147-L151 HydrophobicContact CD1-CD1 4.07Å; Y147-L151 HydrophobicContact CE1-CD1 3.66Å; Y147-L151 HydrophobicContact CE1-CG 4.2Å; Y147-L151 HydrophobicContact CE2-CD2 4.34Å; Y147-L151 HydrophobicContact CE2-CG 4.3Å; Y147-L151 WeakPolarHBondContact O-CG 3.43Å; Y147-L151 PolarHBondContact O-N 3.16Å; I148-L151 PolarHBondContact O-N 3.39Å; L151-I373 HydrophobicContact CB-CD1 3.81Å; L151-I373 HydrophobicContact CD1-CD1 4.46Å
152A98Very high97.8Very high11 Ų1139 Ų399%0.09121%0.214CC..Hα-helixtrans-86.7-7.8-178.700000114.3I148 A149 E150 V154 I373 Q377 L407I148-A152 WeakPolarHBondContact O-CB 3.32Å; I148-A152 PolarHBondContact O-N 3.01Å; A149-A152 PolarHBondContact O-N 3.29Å; E150-A152 VanDerWaalsContact C-N 3.26Å; E150-A152 PolarHBondContact O-N 3.04Å; A152-V154 VanDerWaalsContact C-N 3.31Å; A152-V154 HydrophobicContact CB-CG2 3.98Å; A152-I373 HydrophobicContact CB-CG2 3.93Å; A152-Q377 PolarHBondContact O-NE2 3.06Å; A152-L407 HydrophobicContact CB-CD2 3.61Å
153G97.4Very high97.9Very high63 Ų6336.1 Ų36.165%0.64920%0.197SC*.THydrogen-bonded Turntrans71.422.6-173.900000114.1A149 E150A149-G153 PolarHBondContact O-N 3.47Å; E150-G153 PolarHBondContact O-N 2.88Å
154V96.4Very high97.9Very high33 Ų3334.3 Ų34.320%0.218%0.184CC..  trans-87.9124.6179.6173.60000109.9A149 A152 N156 G406 A408A149-V154 HydrophobicContact CB-CB 4.1Å; A149-V154 HydrophobicContact CB-CG1 4.41Å; A149-V154 PolarHBondContact O-N 2.89Å; A152-V154 VanDerWaalsContact C-N 3.31Å; A152-V154 HydrophobicContact CB-CG2 3.98Å; V154-N156 WeakPolarHBondContact CG1-O 3.28Å; V154-G406 WeakPolarHBondContact CB-O 3.3Å; V154-A408 HydrophobicContact CG1-CB 3.72Å
155K93.7Very high97.9Very high186 Ų18633.1 Ų33.181%0.80918%0.178SC*.SBendtrans-88.3-50179.7-65.2-177.8179.4179.40112.9
156N94.9Very high97.9Very high143 Ų14333.1 Ų33.177%0.76518%0.178SC*.SBendtrans-105.6113.2-178-61.3-45.5000108.3V154V154-N156 WeakPolarHBondContact CG1-O 3.28Å
157V97Very high97.9Very high12 Ų1230 Ų307%0.07317%0.166CC..  trans-78.7160.2173.1-61.60000110.4Y145 A149 V405 L436Y145-V157 HydrophobicContact CD2-CG1 4.2Å; Y145-V157 HydrophobicContact CD2-CG2 4.38Å; Y145-V157 HydrophobicContact CE2-CG2 4.09Å; A149-V157 HydrophobicContact CB-CG1 3.85Å; V157-V405 HydrophobicContact CB-CG1 3.79Å; V157-V405 WeakPolarHBondContact CB-O 3.5Å; V157-V405 HydrophobicContact CG1-CG1 4.41Å; V157-V405 HydrophobicContact CG2-CG1 4.16Å; V157-L436 HydrophobicContact CG2-CD1 4.17Å; V157-L436 HydrophobicContact CG2-CD2 3.77Å
158I97.9Very high97.8Very high17 Ų1729.9 Ų29.99%0.08717%0.165CC..  trans-144.9144.3178.2-158.9171.3000110.8A408 K443 A445 P452I158-A408 HydrophobicContact CG2-CB 3.93Å; I158-K443 HydrophobicContact CG1-CB 4.14Å; I158-K443 VanDerWaalsContact CG1-O 3.22Å; I158-K443 WeakPolarHBondContact CG1-O 3.39Å; I158-A445 HydrophobicContact CD1-CB 3.92Å; I158-A445 HydrophobicContact CG1-CB 4.4Å; I158-P452 HydrophobicContact CD1-CB 3.42Å; I158-P452 VanDerWaalsContact CD1-CB 3.42Å; I158-P452 HydrophobicContact CG1-CB 4.47Å; I158-P452 HydrophobicContact CG2-CB 3.82Å; I158-P452 HydrophobicContact CG2-CG 4.08Å
159L98.6Very high97.8Very high1 Ų129.9 Ų29.91%0.00517%0.165CC..BIsolated β-bridgetrans-77.1135.5172.6-66.7160.1000110F192 V405 I432 E433 L436 A442 K443 Y444 A445L159-F192 HydrophobicContact CB-CB 4.15Å; L159-F192 HydrophobicContact CD1-CB 4.18Å; L159-V405 HydrophobicContact CD2-CG2 4.3Å; L159-I432 HydrophobicContact CD2-CG2 4.2Å; L159-E433 HydrophobicContact CD1-CB 3.65Å; L159-E433 HydrophobicContact CD1-CG 3.6Å; L159-E433 HydrophobicContact CD2-CB 4.02Å; L159-E433 HydrophobicContact CG-CB 4.5Å; L159-L436 HydrophobicContact CD2-CD1 4.29Å; L159-L436 HydrophobicContact CG-CD1 4.18Å; L159-A442 HydrophobicContact CD1-CB 4.49Å; L159-K443 WeakPolarHBondContact CB-O 3.48Å; L159-K443 PolarHBondContact N-O 3.32Å; L159-Y444 HydrophobicContact CB-CD2 4.36Å; L159-A445 WeakPolarHBondContact O-CB 3.18Å; L159-A445 PolarHBondContact O-N 3.22Å
160P98.7Very high97.6Very high0 Ų029.7 Ų29.70%016%0.164CC..PPolyproline II helixtrans-83.6154.8-172.735.9-39.1000112.8P162 F192 V404 G410 I412 L429 Y444P160-P162 WeakPolarHBondContact O-CD 3.22Å; P160-F192 WeakPolarHBondContact O-CD2 3.38Å; P160-V404 HydrophobicContact CB-CG1 4.27Å; P160-V404 HydrophobicContact CB-CG2 3.62Å; P160-V404 HydrophobicContact CG-CG1 3.72Å; P160-V404 HydrophobicContact CG-CG2 4.03Å; P160-G410 CarbonylContact C-O 3.47Å; P160-G410 WeakPolarHBondContact CA-O 3.29Å; P160-I412 HydrophobicContact CB-CB 4.11Å; P160-I412 HydrophobicContact CB-CG2 3.88Å; P160-I412 HydrophobicContact CG-CB 4.06Å; P160-I412 HydrophobicContact CG-CG2 3.55Å; P160-L429 HydrophobicContact CG-CD1 3.9Å; P160-L429 HydrophobicContact CG-CD2 3.99Å; P160-Y444 WeakPolarHBondContact O-CE2 2.99Å
161V98.9Very high97.4Very high0 Ų027 Ų270%016%0.157CC..EExtended strand (participates in β ladder)trans-73.2122.7160.8177.30000109.2M185 V187 G410 Q411 I412 Y444 A445 G446 F449V161-M185 HydrophobicContact CG1-CB 4.24Å; V161-M185 HydrophobicContact CG1-CE 4.11Å; V161-V187 HydrophobicContact CG1-CG1 4.14Å; V161-G410 PolarHBondContact N-O 2.76Å; V161-Q411 WeakPolarHBondContact O-CA 3.42Å; V161-I412 PolarHBondContact O-N 3Å; V161-Y444 HydrophobicContact CB-CE2 4.44Å; V161-Y444 HydrophobicContact CG2-CE1 4.09Å; V161-Y444 HydrophobicContact CG2-CE2 3.98Å; V161-Y444 WeakPolarHBondContact CG2-OH 3.39Å; V161-A445 HydrophobicContact CG2-CB 4.15Å; V161-G446 WeakPolarHBondContact CG2-O 3.35Å; V161-F449 HydrophobicContact CB-CB 4.11Å; V161-F449 HydrophobicContact CG2-CB 3.72Å
162P98.8Very high97.1Very high0 Ų025 Ų250%015%0.146CC..EExtended strand (participates in β ladder)trans-74.9130173.730.6-33.8000110.9P160 F164 P186 F192 A195 I412 Y426P160-P162 WeakPolarHBondContact O-CD 3.22Å; P162-F164 HydrophobicContact CB-CD1 4.42Å; P162-F164 HydrophobicContact CB-CD2 4.37Å; P162-F164 HydrophobicContact CB-CE1 3.89Å; P162-F164 HydrophobicContact CB-CE2 3.86Å; P162-F164 HydrophobicContact CB-CZ 3.59Å; P162-F164 HydrophobicContact CG-CD2 4.29Å; P162-F164 HydrophobicContact CG-CE1 4.19Å; P162-F164 HydrophobicContact CG-CE2 3.44Å; P162-F164 VanDerWaalsContact CG-CE2 3.44Å; P162-F164 HydrophobicContact CG-CZ 3.36Å; P162-P186 HydrophobicContact CG-CG 3.89Å; P162-P186 WeakPolarHBondContact O-CD 3.5Å; P162-F192 HydrophobicContact CB-CE2 4.3Å; P162-F192 HydrophobicContact CG-CE2 4.09Å; P162-A195 HydrophobicContact CG-CB 4.18Å; P162-I412 CarbonylContact C-O 3.6Å; P162-I412 WeakPolarHBondContact CA-O 2.96Å; P162-I412 HydrophobicContact CB-CG2 4.33Å; P162-Y426 HydrophobicContact CB-CD1 4.46Å; P162-Y426 HydrophobicContact CB-CE1 3.66Å
163A98.8Very high97Very high0 Ų025.1 Ų25.10%015%0.147CC..EExtended strand (participates in β ladder)trans-92.4104.6162.500000107.7N165 M183 L184 M185 M387 I412 K413A163-N165 PolarHBondContact O-OD1 3.29Å; A163-M183 HydrophobicContact CB-CB 4.4Å; A163-M183 HydrophobicContact CB-SD 3.71Å; A163-L184 WeakPolarHBondContact CA-O 3.42Å; A163-M185 HydrophobicContact CB-CG 4.15Å; A163-M387 HydrophobicContact CB-CE 4.45Å; A163-M387 HydrophobicContact CB-SD 4.48Å; A163-I412 PolarHBondContact N-O 2.79Å; A163-K413 HydrophobicContact CB-CB 4.31Å
164F98.8Very high96.7Very high0 Ų026.5 Ų26.50%016%0.162CC..EExtended strand (participates in β ladder)trans-87.8113.6-177.9-63-71.9000110.8P162 V166 M183 L184 P186 M196 G415 P417 Y426P162-F164 HydrophobicContact CB-CD1 4.42Å; P162-F164 HydrophobicContact CB-CD2 4.37Å; P162-F164 HydrophobicContact CB-CE1 3.89Å; P162-F164 HydrophobicContact CB-CE2 3.86Å; P162-F164 HydrophobicContact CB-CZ 3.59Å; P162-F164 HydrophobicContact CG-CD2 4.29Å; P162-F164 HydrophobicContact CG-CE1 4.19Å; P162-F164 HydrophobicContact CG-CE2 3.44Å; P162-F164 VanDerWaalsContact CG-CE2 3.44Å; P162-F164 HydrophobicContact CG-CZ 3.36Å; F164-V166 HydrophobicContact CB-CG1 3.89Å; F164-V166 WeakPolarHBondContact O-CG1 3.16Å; F164-V166 PolarHBondContact O-N 3.25Å; F164-M183 CarbonylContact O-C 3.57Å; F164-M183 WeakPolarHBondContact O-CA 3.27Å; F164-L184 HydrophobicContact CB-CB 4.31Å; F164-L184 HydrophobicContact CD2-CB 4.33Å; F164-L184 PolarHBondContact N-O 2.84Å; F164-L184 PolarHBondContact O-N 3.34Å; F164-P186 HydrophobicContact CE2-CG 4.05Å; F164-M196 HydrophobicContact CE1-CE 4.1Å; F164-M196 HydrophobicContact CE1-SD 3.63Å; F164-M196 HydrophobicContact CZ-CE 4.32Å; F164-M196 HydrophobicContact CZ-SD 3.53Å; F164-M196 VanDerWaalsContact CZ-SD 3.53Å; F164-G415 WeakPolarHBondContact CA-O 3.49Å; F164-P417 HydrophobicContact CD1-CB 4.16Å; F164-P417 HydrophobicContact CD1-CG 4.3Å; F164-P417 HydrophobicContact CE1-CB 4.13Å; F164-Y426 HydrophobicContact CD1-CE1 4.14Å; F164-Y426 AromaticContact CD1-CE2 3.89Å; F164-Y426 HydrophobicContact CD1-CE2 3.89Å; F164-Y426 AromaticContact CD1-CZ 3.48Å; F164-Y426 VanDerWaalsContact CD1-CZ 3.48Å; F164-Y426 VanDerWaalsContact CD1-OH 3.23Å; F164-Y426 WeakPolarHBondContact CD1-OH 3.48Å; F164-Y426 HydrophobicContact CE1-CD1 4.22Å; F164-Y426 HydrophobicContact CE1-CD2 4.36Å; F164-Y426 AromaticContact CE1-CE1 3.64Å; F164-Y426 HydrophobicContact CE1-CE1 3.64Å; F164-Y426 AromaticContact CE1-CE2 3.8Å; F164-Y426 HydrophobicContact CE1-CE2 3.8Å; F164-Y426 AromaticContact CE1-CZ 3.4Å; F164-Y426 VanDerWaalsContact CE1-CZ 3.4Å; F164-Y426 HydrophobicContact CZ-CE1 4.46Å
165N97.9Very high96.6Very high0 Ų025.4 Ų25.40%016%0.155CC..EExtended strand (participates in β ladder)trans-76.996.5179.3-48.8-3.7000108.7A163 E181 M183 E224 G226 H390 K413 G415 A416A163-N165 PolarHBondContact O-OD1 3.29Å; N165-E181 VanDerWaalsContact CG-OE2 3.29Å; N165-E181 PolarHBondContact ND2-OE2 3.12Å; N165-M183 HydrophobicContact CB-CG 4.31Å; N165-M183 WeakPolarHBondContact OD1-CG 3.09Å; N165-M183 PolarHBondContact OD1-SD 3.01Å; N165-E224 HydrophobicContact CB-CB 4.41Å; N165-E224 PolarHBondContact ND2-OE2 3.39Å; N165-G226 VanDerWaalsContact O-CA 3.27Å; N165-G226 WeakPolarHBondContact O-CA 3.15Å; N165-G226 PolarHBondContact O-N 3.02Å; N165-H390 PolarHBondContact ND2-NE2 2.87Å; N165-H390 VanDerWaalsContact ND2-NE2 3.16Å; N165-K413 WeakPolarHBondContact ND2-CE 3.24Å; N165-G415 PolarHBondContact N-O 3.17Å; N165-G415 VanDerWaalsContact N-O 3.16Å; N165-A416 WeakPolarHBondContact O-CA 3.41Å; N165-A416 WeakPolarHBondContact O-CB 3.31Å; N165-A416 PolarHBondContact O-N 3.25Å
166V98.6Very high96.7Very high0 Ų022 Ų220%014%0.14CC..EExtended strand (participates in β ladder)trans-107.8-14.9-168.2-66.80000114.3F164 F182 L184 Y203 L206 G226 F227 L241F164-V166 HydrophobicContact CB-CG1 3.89Å; F164-V166 WeakPolarHBondContact O-CG1 3.16Å; F164-V166 PolarHBondContact O-N 3.25Å; V166-F182 WeakPolarHBondContact CG2-O 3.39Å; V166-F182 PolarHBondContact N-O 3.44Å; V166-L184 HydrophobicContact CB-CD1 4.46Å; V166-L184 HydrophobicContact CG1-CD1 3.76Å; V166-L184 HydrophobicContact CG1-CG 4.11Å; V166-L184 HydrophobicContact CG2-CD1 4.04Å; V166-L184 HydrophobicContact CG2-CD2 4.33Å; V166-L184 HydrophobicContact CG2-CG 3.71Å; V166-Y203 HydrophobicContact CB-CD2 4.06Å; V166-Y203 HydrophobicContact CG1-CD2 3.72Å; V166-L206 HydrophobicContact CB-CD2 3.79Å; V166-L206 HydrophobicContact CG2-CD2 3.78Å; V166-G226 VanDerWaalsContact C-CA 3.48Å; V166-G226 CarbonylContact O-C 3.57Å; V166-G226 WeakPolarHBondContact O-CA 3.34Å; V166-F227 WeakPolarHBondContact O-CD2 3.42Å; V166-F227 PolarHBondContact O-N 3.08Å; V166-L241 HydrophobicContact CG2-CD2 3.51Å
167I98.6Very high96.8Very high0 Ų015.1 Ų15.10%010%0.103CC..EExtended strand (participates in β ladder)trans-129128.8166.3-58.4175.5000107.5L177 E181 F182 L206 F227 P229 A237 L240 L241I167-L177 HydrophobicContact CG2-CD2 3.94Å; I167-E181 WeakPolarHBondContact O-CA 3.27Å; I167-F182 HydrophobicContact CB-CB 4.1Å; I167-F182 HydrophobicContact CB-CD2 4.11Å; I167-F182 HydrophobicContact CB-CG 4.42Å; I167-F182 HydrophobicContact CG2-CD2 4.08Å; I167-F182 PolarHBondContact N-O 2.8Å; I167-F182 PolarHBondContact O-N 2.81Å; I167-L206 HydrophobicContact CD1-CD1 4.35Å; I167-L206 HydrophobicContact CD1-CD2 4.4Å; I167-L206 HydrophobicContact CG1-CD2 3.95Å; I167-F227 CarbonylContact C-O 3.55Å; I167-F227 VanDerWaalsContact CA-O 3.26Å; I167-F227 WeakPolarHBondContact CA-O 2.92Å; I167-P229 HydrophobicContact CG2-CG 4.42Å; I167-A237 HydrophobicContact CD1-CB 3.97Å; I167-A237 HydrophobicContact CG2-CB 4.38Å; I167-L240 HydrophobicContact CD1-CB 4.35Å; I167-L240 HydrophobicContact CD1-CD1 4.39Å; I167-L241 HydrophobicContact CD1-CD2 3.76Å; I167-L241 HydrophobicContact CD1-CG 4.05Å; I167-L241 HydrophobicContact CG1-CD2 4.13Å
168N97.8Very high96.8Very high0 Ų014.7 Ų14.70%010%0.1CC..EExtended strand (participates in β ladder)trans-109.9140.1175.9-67.3136.2000111.2H172 A173 N175 Q180 G226 F227N168-H172 HydrophobicContact CB-CB 4.37Å; N168-A173 HydrophobicContact CB-CB 3.98Å; N168-A173 WeakPolarHBondContact O-CB 3.42Å; N168-N175 PolarHBondContact O-ND2 2.89Å; N168-Q180 CarbonylContact C-O 3.59Å; N168-Q180 WeakPolarHBondContact CA-O 3.2Å; N168-G226 VanDerWaalsContact OD1-CA 3.27Å; N168-G226 WeakPolarHBondContact OD1-CA 3.38Å; N168-G226 PolarHBondContact OD1-N 3.27Å; N168-G226 PolarHBondContact OD1-O 2.89Å; N168-F227 PolarHBondContact N-O 2.91Å
169G97.1Very high96.7Very high0 Ų013.9 Ų13.90%010%0.096CC..  trans-135.7-149.2170.500000109.5H172 A173 N175 M179 Q180G169-H172 PolarHBondContact O-N 3.31Å; G169-H172 VanDerWaalsContact O-N 3.13Å; G169-A173 PolarHBondContact O-N 2.55Å; G169-N175 WeakPolarHBondContact CA-OD1 3.2Å; G169-M179 VanDerWaalsContact CA-O 3.29Å; G169-M179 WeakPolarHBondContact CA-O 3.49Å; G169-Q180 PolarHBondContact N-O 2.99Å
170G95.7Very high96.7Very high1 Ų114.1 Ų14.11%0.0110%0.098CC..G310 helixtrans50.6-143.6174.100000113.1H172 A173 L177 A178 K280G170-H172 PolarHBondContact O-N 3.13Å; G170-A173 VanDerWaalsContact O-O 3.14Å; G170-L177 PolarHBondContact N-O 3.38Å; G170-A178 VanDerWaalsContact CA-O 3.27Å; G170-A178 WeakPolarHBondContact CA-O 3.24Å; G170-A178 PolarHBondContact N-O 2.86Å; G170-K280 WeakPolarHBondContact O-CE 3.46Å; G170-K280 PolarHBondContact O-NZ 2.8Å
171S93.8Very high96.7Very high48 Ų4814.2 Ų14.234%0.33610%0.098SC..G310 helixtrans-74-6.7179.5-68.80000113.7E264S171-E264 PolarHBondContact OG-OE2 3Å
172H92.8Very high96.7Very high10 Ų1014.2 Ų14.25%0.04610%0.098CC..G310 helixtrans-91.6-5.6-179.4-66.1177.2000113.9N168 G169 G170 Q180 E181 G222 D223 E224N168-H172 HydrophobicContact CB-CB 4.37Å; G169-H172 PolarHBondContact O-N 3.31Å; G169-H172 VanDerWaalsContact O-N 3.13Å; G170-H172 PolarHBondContact O-N 3.13Å; H172-Q180 HydrophobicContact CB-CG 4.11Å; H172-Q180 VanDerWaalsContact CE1-CD 3.49Å; H172-Q180 PolarHBondContact CE1-NE2 3.3Å; H172-Q180 VanDerWaalsContact CE1-NE2 3.3Å; H172-Q180 WeakPolarHBondContact ND1-CG 3.43Å; H172-E181 IonicContact CE1-OE1 3.69Å; H172-E181 PolarHBondContact CE1-OE1 2.86Å; H172-E181 IonicContact ND1-OE1 3.14Å; H172-E181 PolarHBondContact ND1-OE1 3.33Å; H172-G222 VanDerWaalsContact O-CA 3.29Å; H172-G222 WeakPolarHBondContact O-CA 3.35Å; H172-D223 HydrophobicContact CB-CB 4.42Å; H172-D223 PolarHBondContact O-N 3.17Å; H172-E224 IonicContact CE1-OE1 3.06Å; H172-E224 PolarHBondContact CE1-OE1 3.44Å; H172-E224 IonicContact ND1-OE1 3.92Å; H172-E224 IonicContact ND1-OE2 3.18Å
173A94.6Very high96.7Very high14 Ų1414.3 Ų14.312%0.11610%0.098CC..  trans-149.2147.2-178.600000113.6N168 G169 G170 N175 A228 K280N168-A173 HydrophobicContact CB-CB 3.98Å; N168-A173 WeakPolarHBondContact O-CB 3.42Å; G169-A173 PolarHBondContact O-N 2.55Å; G170-A173 VanDerWaalsContact O-O 3.14Å; A173-N175 PolarHBondContact O-N 3.37Å; A173-A228 HydrophobicContact CB-CB 3.76Å; A173-K280 PolarHBondContact O-NZ 3Å
174G92.3Very high96.7Very high92 Ų9214.3 Ų14.395%0.94810%0.098SC*.SBendtrans-79.910.3177.900000115.8
175N94.3Very high96.7Very high10 Ų1014.3 Ų14.35%0.05310%0.098CC..SBendtrans-86179177.663.211.3000112N168 G169 A173 L177 P229 K280N168-N175 PolarHBondContact O-ND2 2.89Å; G169-N175 WeakPolarHBondContact CA-OD1 3.2Å; A173-N175 PolarHBondContact O-N 3.37Å; N175-L177 PolarHBondContact OD1-N 2.7Å; N175-P229 WeakPolarHBondContact CB-O 3.36Å; N175-P229 PolarHBondContact ND2-O 2.68Å; N175-K280 WeakPolarHBondContact O-CD 3.22Å; N175-K280 WeakPolarHBondContact O-CE 3.23Å; N175-K280 PolarHBondContact O-NZ 3.44Å
176K94.4Very high96.7Very high113 Ų11314.3 Ų14.349%0.49110%0.098SC..SBendtrans-81.3-8.2179-69.4-176.1177.4-170.40115.4A178 N230 P232K176-A178 PolarHBondContact O-N 3.12Å; K176-N230 WeakPolarHBondContact CG-OD1 3.4Å; K176-P232 HydrophobicContact CB-CB 4.12Å
177L96.6Very high96.7Very high0 Ų014.4 Ų14.40%010%0.099CC..  trans-65.8123.9-176-171.256.9000109.8I167 G170 N175 F182 I231 P234 A237 K280I167-L177 HydrophobicContact CG2-CD2 3.94Å; G170-L177 PolarHBondContact N-O 3.38Å; N175-L177 PolarHBondContact OD1-N 2.7Å; L177-F182 HydrophobicContact CD1-CE2 4.24Å; L177-F182 HydrophobicContact CD1-CZ 4.21Å; L177-F182 HydrophobicContact CD2-CD2 4.1Å; L177-F182 HydrophobicContact CD2-CE2 3.42Å; L177-F182 VanDerWaalsContact CD2-CE2 3.42Å; L177-F182 HydrophobicContact CD2-CZ 4.16Å; L177-F182 HydrophobicContact CG-CE2 4.01Å; L177-F182 HydrophobicContact CG-CZ 4.47Å; L177-I231 WeakPolarHBondContact CB-O 3.22Å; L177-I231 HydrophobicContact CD2-CG1 4.41Å; L177-P234 HydrophobicContact CD1-CB 4.39Å; L177-P234 HydrophobicContact CD1-CG 4.11Å; L177-A237 HydrophobicContact CD2-CB 4.34Å; L177-K280 PolarHBondContact O-NZ 2.88Å; L177-K280 VanDerWaalsContact O-NZ 3.16Å
178A96.8Very high96.7Very high2 Ų215.8 Ų15.82%0.01711%0.113CC..  trans-76.3-45.8-178.300000112.8G170 K176 F265 L277 F279G170-A178 VanDerWaalsContact CA-O 3.27Å; G170-A178 WeakPolarHBondContact CA-O 3.24Å; G170-A178 PolarHBondContact N-O 2.86Å; K176-A178 PolarHBondContact O-N 3.12Å; A178-F265 HydrophobicContact CB-CD1 4.29Å; A178-F265 HydrophobicContact CB-CE1 4.44Å; A178-L277 HydrophobicContact CB-CB 4.26Å; A178-L277 HydrophobicContact CB-CD2 4.11Å; A178-L277 WeakPolarHBondContact CB-O 3.46Å; A178-F279 HydrophobicContact CB-CD1 4.22Å; A178-F279 HydrophobicContact CB-CE1 4.2Å
179M97.6Very high96.7Very high0 Ų016.1 Ų16.10%012%0.116CC..SBendtrans-68.1134.4178.7-61.5-176.617900110.2G169 F182 P234 M258 V260 L298 Y299 Y302G169-M179 VanDerWaalsContact CA-O 3.29Å; G169-M179 WeakPolarHBondContact CA-O 3.49Å; M179-F182 HydrophobicContact CB-CE2 4Å; M179-F182 HydrophobicContact CB-CZ 3.83Å; M179-F182 HydrophobicContact SD-CZ 4.42Å; M179-P234 HydrophobicContact CE-CB 4.31Å; M179-P234 HydrophobicContact CE-CG 3.93Å; M179-P234 HydrophobicContact CG-CB 4.41Å; M179-P234 HydrophobicContact CG-CG 3.98Å; M179-P234 HydrophobicContact SD-CB 3.61Å; M179-P234 HydrophobicContact SD-CG 3.64Å; M179-M258 HydrophobicContact SD-CE 3.31Å; M179-M258 WeakPolarHBondContact SD-CE 3.25Å; M179-V260 HydrophobicContact CG-CG1 4.31Å; M179-V260 HydrophobicContact SD-CG2 4.4Å; M179-L298 HydrophobicContact CE-CD2 4.09Å; M179-Y299 HydrophobicContact CE-CE1 3.84Å; M179-Y302 HydrophobicContact CE-CE2 3.81Å; M179-Y302 HydrophobicContact SD-CE2 4.18Å
180Q97.7Very high96.8Very high7 Ų721.3 Ų21.33%0.03315%0.15CC..  trans-75.3-40.2-163.9-167162.4-99.300113.4N168 G169 H172 D259 V260 A261N168-Q180 CarbonylContact C-O 3.59Å; N168-Q180 WeakPolarHBondContact CA-O 3.2Å; G169-Q180 PolarHBondContact N-O 2.99Å; H172-Q180 HydrophobicContact CB-CG 4.11Å; H172-Q180 VanDerWaalsContact CE1-CD 3.49Å; H172-Q180 PolarHBondContact CE1-NE2 3.3Å; H172-Q180 VanDerWaalsContact CE1-NE2 3.3Å; H172-Q180 WeakPolarHBondContact ND1-CG 3.43Å; Q180-D259 PolarHBondContact N-O 2.8Å; Q180-D259 PolarHBondContact NE2-OD2 2.83Å; Q180-D259 VanDerWaalsContact NE2-OD2 3.16Å; Q180-V260 PolarHBondContact N-O 3.2Å; Q180-A261 HydrophobicContact CB-CB 3.78Å; Q180-A261 HydrophobicContact CG-CB 4.36Å
181E98Very high96.9Very high2 Ų222.4 Ų22.41%0.00916%0.157CC..EExtended strand (participates in β ladder)trans-149.2140.8-172-41.4170.9-175.200112.9N165 I167 H172 E224 M258 D259 K413N165-E181 VanDerWaalsContact CG-OE2 3.29Å; N165-E181 PolarHBondContact ND2-OE2 3.12Å; I167-E181 WeakPolarHBondContact O-CA 3.27Å; H172-E181 IonicContact CE1-OE1 3.69Å; H172-E181 PolarHBondContact CE1-OE1 2.86Å; H172-E181 IonicContact ND1-OE1 3.14Å; H172-E181 PolarHBondContact ND1-OE1 3.33Å; E181-E224 VanDerWaalsContact OE1-CD 3.32Å; E181-M258 WeakPolarHBondContact O-CA 3.3Å; E181-D259 HydrophobicContact CB-CB 3.89Å; E181-D259 HydrophobicContact CG-CB 3.98Å; E181-D259 PolarHBondContact N-O 2.75Å; E181-D259 PolarHBondContact O-N 3.07Å; E181-K413 IonicContact OE1-NZ 3.89Å; E181-K413 WeakPolarHBondContact OE2-CE 3.15Å; E181-K413 IonicContact OE2-NZ 2.85Å; E181-K413 PolarHBondContact OE2-NZ 3.08Å
182F98.7Very high97.1Very high0 Ų020.1 Ų20.10%014%0.142CC..EExtended strand (participates in β ladder)trans-122.6124.9171.6-55-109.8000108.3V166 I167 L177 M179 P234 A237 L238 L241 M258V166-F182 WeakPolarHBondContact CG2-O 3.39Å; V166-F182 PolarHBondContact N-O 3.44Å; I167-F182 HydrophobicContact CB-CB 4.1Å; I167-F182 HydrophobicContact CB-CD2 4.11Å; I167-F182 HydrophobicContact CB-CG 4.42Å; I167-F182 HydrophobicContact CG2-CD2 4.08Å; I167-F182 PolarHBondContact N-O 2.8Å; I167-F182 PolarHBondContact O-N 2.81Å; L177-F182 HydrophobicContact CD1-CE2 4.24Å; L177-F182 HydrophobicContact CD1-CZ 4.21Å; L177-F182 HydrophobicContact CD2-CD2 4.1Å; L177-F182 HydrophobicContact CD2-CE2 3.42Å; L177-F182 VanDerWaalsContact CD2-CE2 3.42Å; L177-F182 HydrophobicContact CD2-CZ 4.16Å; L177-F182 HydrophobicContact CG-CE2 4.01Å; L177-F182 HydrophobicContact CG-CZ 4.47Å; M179-F182 HydrophobicContact CB-CE2 4Å; M179-F182 HydrophobicContact CB-CZ 3.83Å; M179-F182 HydrophobicContact SD-CZ 4.42Å; F182-P234 HydrophobicContact CE1-CB 4.16Å; F182-P234 HydrophobicContact CZ-CB 3.86Å; F182-A237 HydrophobicContact CD1-CB 3.84Å; F182-A237 HydrophobicContact CD2-CB 4.04Å; F182-A237 HydrophobicContact CE1-CB 3.68Å; F182-A237 HydrophobicContact CE2-CB 3.96Å; F182-A237 HydrophobicContact CG-CB 4.02Å; F182-A237 HydrophobicContact CZ-CB 3.75Å; F182-L238 HydrophobicContact CD1-CD2 3.84Å; F182-L238 HydrophobicContact CD1-CG 4.08Å; F182-L238 HydrophobicContact CE1-CD2 4.18Å; F182-L238 HydrophobicContact CE1-CG 3.99Å; F182-L241 HydrophobicContact CB-CD1 3.67Å; F182-M258 HydrophobicContact CD1-CE 4.3Å; F182-M258 HydrophobicContact CD1-CG 4.2Å; F182-M258 HydrophobicContact CE1-CE 3.71Å; F182-M258 HydrophobicContact CE1-SD 4.48Å; F182-M258 HydrophobicContact CZ-CE 4.28Å
183M98.8Very high97.4Very high1 Ų125.6 Ų25.61%0.00517%0.165CC..EExtended strand (participates in β ladder)trans-118.6146.5-164.2-65.6177.8-90.500112.6A163 F164 N165 I256 A257 D259 K413A163-M183 HydrophobicContact CB-CB 4.4Å; A163-M183 HydrophobicContact CB-SD 3.71Å; F164-M183 CarbonylContact O-C 3.57Å; F164-M183 WeakPolarHBondContact O-CA 3.27Å; N165-M183 HydrophobicContact CB-CG 4.31Å; N165-M183 WeakPolarHBondContact OD1-CG 3.09Å; N165-M183 PolarHBondContact OD1-SD 3.01Å; M183-I256 WeakPolarHBondContact O-CA 3.46Å; M183-A257 HydrophobicContact CB-CB 3.96Å; M183-A257 HydrophobicContact CE-CB 3.98Å; M183-A257 PolarHBondContact N-O 3.28Å; M183-A257 PolarHBondContact O-N 2.76Å; M183-D259 HydrophobicContact CE-CB 4.12Å; M183-K413 HydrophobicContact CE-CD 4.49Å; M183-K413 HydrophobicContact SD-CD 3.9Å; M183-K413 HydrophobicContact SD-CG 4.12Å
184L98.9Very high97.6Very high0 Ų027.6 Ų27.60%017%0.172CC..EExtended strand (participates in β ladder)trans-98.1132.5168.4-55.8171.4000109.7A163 F164 V166 V202 L241 I245 I254A163-L184 WeakPolarHBondContact CA-O 3.42Å; F164-L184 HydrophobicContact CB-CB 4.31Å; F164-L184 HydrophobicContact CD2-CB 4.33Å; F164-L184 PolarHBondContact N-O 2.84Å; F164-L184 PolarHBondContact O-N 3.34Å; V166-L184 HydrophobicContact CB-CD1 4.46Å; V166-L184 HydrophobicContact CG1-CD1 3.76Å; V166-L184 HydrophobicContact CG1-CG 4.11Å; V166-L184 HydrophobicContact CG2-CD1 4.04Å; V166-L184 HydrophobicContact CG2-CD2 4.33Å; V166-L184 HydrophobicContact CG2-CG 3.71Å; L184-V202 HydrophobicContact CD1-CB 3.64Å; L184-V202 HydrophobicContact CD1-CG1 3.42Å; L184-V202 VanDerWaalsContact CD1-CG1 3.42Å; L184-V202 HydrophobicContact CD2-CG1 3.97Å; L184-V202 HydrophobicContact CG-CG1 4.35Å; L184-L241 HydrophobicContact CD2-CD1 4.47Å; L184-L241 HydrophobicContact CD2-CD2 4.19Å; L184-I245 HydrophobicContact CD2-CD1 3.86Å; L184-I245 HydrophobicContact CD2-CG1 3.96Å; L184-I254 HydrophobicContact CB-CG2 3.94Å; L184-I254 HydrophobicContact CD2-CG2 4Å
185M98.8Very high97.9Very high0 Ų023.2 Ų23.20%013%0.127CC..EExtended strand (participates in β ladder)trans-122.3101.6174.6-64.6-170.576.700110.4V161 A163 V187 I254 K255 A257 V309 M387 F449V161-M185 HydrophobicContact CG1-CB 4.24Å; V161-M185 HydrophobicContact CG1-CE 4.11Å; A163-M185 HydrophobicContact CB-CG 4.15Å; M185-V187 HydrophobicContact CB-CG1 4.17Å; M185-V187 PolarHBondContact O-N 3.43Å; M185-I254 WeakPolarHBondContact O-CA 3.16Å; M185-K255 PolarHBondContact N-O 3.15Å; M185-K255 PolarHBondContact O-N 2.71Å; M185-A257 HydrophobicContact CG-CB 4.02Å; M185-A257 HydrophobicContact SD-CB 3.58Å; M185-A257 VanDerWaalsContact SD-CB 3.58Å; M185-V309 HydrophobicContact SD-CG2 3.97Å; M185-M387 HydrophobicContact CE-CE 4.38Å; M185-F449 HydrophobicContact CE-CD2 3.58Å; M185-F449 HydrophobicContact CE-CE2 3.82Å; M185-F449 HydrophobicContact CE-CG 4.38Å
186P98.8Very high98.1Very high0 Ų023.7 Ų23.70%013%0.129CC..  trans-77.463.717935.4-37.8000112.1P162 F164 G188 A189 A195 M198 K253 I254 Y444P162-P186 HydrophobicContact CG-CG 3.89Å; P162-P186 WeakPolarHBondContact O-CD 3.5Å; F164-P186 HydrophobicContact CE2-CG 4.05Å; P186-G188 VanDerWaalsContact C-N 3.27Å; P186-G188 PolarHBondContact O-N 3.4Å; P186-A189 HydrophobicContact CB-CB 4.36Å; P186-A189 WeakPolarHBondContact O-CB 3.35Å; P186-A189 PolarHBondContact O-N 3.22Å; P186-A195 HydrophobicContact CB-CB 4.03Å; P186-A195 HydrophobicContact CG-CB 3.49Å; P186-A195 VanDerWaalsContact CG-CB 3.49Å; P186-M198 HydrophobicContact CB-CB 4.37Å; P186-M198 HydrophobicContact CB-CE 4.1Å; P186-K253 CarbonylContact C-O 3.54Å; P186-I254 HydrophobicContact CB-CG1 4.08Å; P186-Y444 PolarHBondContact O-OH 2.91Å
187V98.6Very high98.3Very high2 Ų222.7 Ų22.71%0.01212%0.122CC..THydrogen-bonded Turntrans-64.4-29.1-179.3-59.80000113.1V161 M185 A189 K253 K255 G446 E447 F449V161-V187 HydrophobicContact CG1-CG1 4.14Å; M185-V187 HydrophobicContact CB-CG1 4.17Å; M185-V187 PolarHBondContact O-N 3.43Å; V187-A189 VanDerWaalsContact C-N 3.31Å; V187-A189 PolarHBondContact O-N 2.88Å; V187-K253 PolarHBondContact N-O 2.96Å; V187-K255 HydrophobicContact CG1-CG 4.41Å; V187-K255 HydrophobicContact CG2-CD 4.36Å; V187-K255 HydrophobicContact CG2-CG 3.5Å; V187-G446 CarbonylContact O-C 3.57Å; V187-G446 WeakPolarHBondContact O-CA 3.38Å; V187-E447 PolarHBondContact O-N 2.94Å; V187-E447 VanDerWaalsContact O-N 3.14Å; V187-F449 HydrophobicContact CG1-CD1 3.96Å; V187-F449 HydrophobicContact CG1-CE1 4.25Å; V187-F449 HydrophobicContact CG1-CG 4.39Å
188G98.4Very high98.5Very high29 Ų2923 Ų2330%0.29912%0.123SC..THydrogen-bonded Turntrans-889.2179.700000114.4P186 K253P186-G188 VanDerWaalsContact C-N 3.27Å; P186-G188 PolarHBondContact O-N 3.4Å; G188-K253 PolarHBondContact N-O 3.48Å
189A98.6Very high98.5Very high8 Ų822.9 Ų22.97%0.06612%0.123CC..  trans-74.4145.717400000111.1P186 V187 E194 A195 M198 Y444P186-A189 HydrophobicContact CB-CB 4.36Å; P186-A189 WeakPolarHBondContact O-CB 3.35Å; P186-A189 PolarHBondContact O-N 3.22Å; V187-A189 VanDerWaalsContact C-N 3.31Å; V187-A189 PolarHBondContact O-N 2.88Å; A189-E194 HydrophobicContact CB-CB 4.41Å; A189-A195 HydrophobicContact CB-CB 3.75Å; A189-M198 HydrophobicContact CB-SD 3.7Å; A189-Y444 HydrophobicContact CB-CE1 3.9Å; A189-Y444 VanDerWaalsContact O-CD1 3.23Å; A189-Y444 WeakPolarHBondContact O-CD1 3.25Å; A189-Y444 VanDerWaalsContact O-CE1 3.29Å; A189-Y444 WeakPolarHBondContact O-CE1 3.48Å
190P97.7Very high98.6Very high109 Ų10924.7 Ų24.771%0.70814%0.135SC*.SBendtrans-79-19.1178.732.1-37.1000113.7E194P190-E194 HydrophobicContact CG-CB 3.92Å; P190-E194 HydrophobicContact CG-CG 3.82Å
191S98.6Very high98.7Very high24 Ų2427.7 Ų27.717%0.16815%0.149CC..SBendtrans-152.8169.6-177.479.50000110.8E194 A195 E433S191-E194 PolarHBondContact O-N 2.93Å; S191-E194 PolarHBondContact OG-N 2.63Å; S191-A195 WeakPolarHBondContact O-CB 3.32Å; S191-A195 PolarHBondContact O-N 3.25Å; S191-E433 VanDerWaalsContact CB-OE1 3.27Å; S191-E433 WeakPolarHBondContact CB-OE1 3.45Å
192F98.8Very high98.7Very high0 Ų027.6 Ų27.60%015%0.149CC..Hα-helixtrans-68.6-40.7177.7178.5-96.2000111.5L159 P160 P162 E194 A195 M196 Y426 L429 L430 E433 Y444L159-F192 HydrophobicContact CB-CB 4.15Å; L159-F192 HydrophobicContact CD1-CB 4.18Å; P160-F192 WeakPolarHBondContact O-CD2 3.38Å; P162-F192 HydrophobicContact CB-CE2 4.3Å; P162-F192 HydrophobicContact CG-CE2 4.09Å; F192-E194 VanDerWaalsContact C-N 3.33Å; F192-E194 PolarHBondContact O-N 2.94Å; F192-A195 VanDerWaalsContact O-CB 3.32Å; F192-A195 WeakPolarHBondContact O-CB 3.42Å; F192-A195 PolarHBondContact O-N 3.08Å; F192-A195 VanDerWaalsContact O-N 3.15Å; F192-M196 HydrophobicContact CD1-CG 4.07Å; F192-M196 HydrophobicContact CE1-CG 3.43Å; F192-M196 VanDerWaalsContact CE1-CG 3.43Å; F192-M196 HydrophobicContact CE1-SD 4.14Å; F192-M196 HydrophobicContact CE2-CG 4.3Å; F192-M196 HydrophobicContact CE2-SD 4.45Å; F192-M196 HydrophobicContact CZ-CG 3.57Å; F192-M196 HydrophobicContact CZ-SD 3.72Å; F192-M196 PolarHBondContact O-N 2.95Å; F192-Y426 HydrophobicContact CZ-CD1 4.06Å; F192-L429 HydrophobicContact CD1-CB 3.85Å; F192-L429 HydrophobicContact CE1-CB 3.26Å; F192-L429 HydrophobicContact CE1-CD1 4.28Å; F192-L429 HydrophobicContact CE1-CG 4.4Å; F192-L429 HydrophobicContact CE2-CB 4.04Å; F192-L429 HydrophobicContact CE2-CD1 3.6Å; F192-L429 HydrophobicContact CE2-CG 4.42Å; F192-L429 HydrophobicContact CG-CB 4.46Å; F192-L429 HydrophobicContact CZ-CB 3.38Å; F192-L429 HydrophobicContact CZ-CD1 3.47Å; F192-L429 VanDerWaalsContact CZ-CD1 3.47Å; F192-L429 HydrophobicContact CZ-CG 4.06Å; F192-L430 HydrophobicContact CD1-CD2 3.88Å; F192-L430 HydrophobicContact CD1-CG 4.31Å; F192-L430 HydrophobicContact CE1-CD2 3.98Å; F192-L430 HydrophobicContact CE1-CG 4Å; F192-E433 WeakPolarHBondContact CA-OE1 3.49Å; F192-E433 WeakPolarHBondContact CB-OE1 3.45Å; F192-E433 PolarHBondContact N-OE1 3.13Å; F192-Y444 HydrophobicContact CB-CD2 4.07Å; F192-Y444 HydrophobicContact CB-CE2 4.43Å; F192-Y444 HydrophobicContact CD2-CE2 4.36Å
193K98.7Very high98.7Very high125 Ų12528.4 Ų28.454%0.54315%0.152SC..Hα-helixtrans-56.7-43.6172.6167.2178.4155.2-170.40112.8M196 R197 L430 E433K193-M196 WeakPolarHBondContact O-CB 3.27Å; K193-M196 PolarHBondContact O-N 2.74Å; K193-R197 PolarHBondContact O-N 2.9Å; K193-L430 HydrophobicContact CB-CD2 3.87Å; K193-L430 HydrophobicContact CG-CD2 4.46Å; K193-E433 WeakPolarHBondContact CA-OE2 3.48Å; K193-E433 WeakPolarHBondContact CB-OE2 3.4Å; K193-E433 PolarHBondContact N-OE1 3.25Å; K193-E433 PolarHBondContact N-OE2 2.97Å
194E98.8Very high98.7Very high55 Ų5534 Ų3426%0.25718%0.178SC..Hα-helixtrans-69.7-36.6176-74.2-57.8116.200111.9A189 P190 S191 F192 M196 R197 M198A189-E194 HydrophobicContact CB-CB 4.41Å; P190-E194 HydrophobicContact CG-CB 3.92Å; P190-E194 HydrophobicContact CG-CG 3.82Å; S191-E194 PolarHBondContact O-N 2.93Å; S191-E194 PolarHBondContact OG-N 2.63Å; F192-E194 VanDerWaalsContact C-N 3.33Å; F192-E194 PolarHBondContact O-N 2.94Å; E194-M196 VanDerWaalsContact C-N 3.32Å; E194-M196 PolarHBondContact O-N 3.09Å; E194-R197 PolarHBondContact O-N 3.31Å; E194-R197 IonicContact OE1-NE 3.71Å; E194-R197 IonicContact OE2-CZ 3.55Å; E194-R197 VanDerWaalsContact OE2-CZ 3.27Å; E194-R197 IonicContact OE2-NE 3.35Å; E194-R197 PolarHBondContact OE2-NE 3.42Å; E194-R197 IonicContact OE2-NH2 2.95Å; E194-R197 PolarHBondContact OE2-NH2 3.46Å; E194-M198 WeakPolarHBondContact O-CB 3.5Å; E194-M198 WeakPolarHBondContact O-CG 3.33Å; E194-M198 PolarHBondContact O-N 3.23Å
195A98.9Very high98.7Very high0 Ų036 Ų360%019%0.189CC..Hα-helixtrans-58.5-43.3171.600000112.2P162 P186 A189 S191 F192 M198 G199 Y444P162-A195 HydrophobicContact CG-CB 4.18Å; P186-A195 HydrophobicContact CB-CB 4.03Å; P186-A195 HydrophobicContact CG-CB 3.49Å; P186-A195 VanDerWaalsContact CG-CB 3.49Å; A189-A195 HydrophobicContact CB-CB 3.75Å; S191-A195 WeakPolarHBondContact O-CB 3.32Å; S191-A195 PolarHBondContact O-N 3.25Å; F192-A195 VanDerWaalsContact O-CB 3.32Å; F192-A195 WeakPolarHBondContact O-CB 3.42Å; F192-A195 PolarHBondContact O-N 3.08Å; F192-A195 VanDerWaalsContact O-N 3.15Å; A195-M198 PolarHBondContact O-N 2.78Å; A195-G199 PolarHBondContact O-N 3.25Å; A195-Y444 HydrophobicContact CB-CE1 4.5Å; A195-Y444 HydrophobicContact CB-CE2 3.97Å; A195-Y444 WeakPolarHBondContact CB-OH 3.26Å
196M98.8Very high98.7Very high20 Ų2036 Ų3610%0.09919%0.189CC..Hα-helixtrans-61.6-47.1174.5-79.1-58.8-5300112.2F164 F192 K193 E194 G199 S200 P417 Y426 L430F164-M196 HydrophobicContact CE1-CE 4.1Å; F164-M196 HydrophobicContact CE1-SD 3.63Å; F164-M196 HydrophobicContact CZ-CE 4.32Å; F164-M196 HydrophobicContact CZ-SD 3.53Å; F164-M196 VanDerWaalsContact CZ-SD 3.53Å; F192-M196 HydrophobicContact CD1-CG 4.07Å; F192-M196 HydrophobicContact CE1-CG 3.43Å; F192-M196 VanDerWaalsContact CE1-CG 3.43Å; F192-M196 HydrophobicContact CE1-SD 4.14Å; F192-M196 HydrophobicContact CE2-CG 4.3Å; F192-M196 HydrophobicContact CE2-SD 4.45Å; F192-M196 HydrophobicContact CZ-CG 3.57Å; F192-M196 HydrophobicContact CZ-SD 3.72Å; F192-M196 PolarHBondContact O-N 2.95Å; K193-M196 WeakPolarHBondContact O-CB 3.27Å; K193-M196 PolarHBondContact O-N 2.74Å; E194-M196 VanDerWaalsContact C-N 3.32Å; E194-M196 PolarHBondContact O-N 3.09Å; M196-G199 PolarHBondContact O-N 3.02Å; M196-S200 VanDerWaalsContact O-CB 3.31Å; M196-S200 WeakPolarHBondContact O-CB 3.02Å; M196-S200 PolarHBondContact O-N 3.44Å; M196-P417 HydrophobicContact CE-CB 4.4Å; M196-Y426 HydrophobicContact CE-CD1 4.35Å; M196-Y426 HydrophobicContact CE-CD2 4.17Å; M196-Y426 HydrophobicContact CE-CG 3.84Å; M196-Y426 HydrophobicContact SD-CD1 3.55Å; M196-Y426 VanDerWaalsContact SD-CD1 3.55Å; M196-Y426 HydrophobicContact SD-CD2 4.38Å; M196-Y426 HydrophobicContact SD-CE1 4.21Å; M196-Y426 HydrophobicContact SD-CG 3.65Å; M196-L430 HydrophobicContact CG-CD2 4.29Å
197R98.8Very high98.7Very high93 Ų9340.5 Ų40.535%0.35121%0.208SC..Hα-helixtrans-59.5-49.9177.1-173.7-176.766.972.56.6111.2K193 E194 G199 S200 E201 Y250K193-R197 PolarHBondContact O-N 2.9Å; E194-R197 PolarHBondContact O-N 3.31Å; E194-R197 IonicContact OE1-NE 3.71Å; E194-R197 IonicContact OE2-CZ 3.55Å; E194-R197 VanDerWaalsContact OE2-CZ 3.27Å; E194-R197 IonicContact OE2-NE 3.35Å; E194-R197 PolarHBondContact OE2-NE 3.42Å; E194-R197 IonicContact OE2-NH2 2.95Å; E194-R197 PolarHBondContact OE2-NH2 3.46Å; R197-G199 PolarHBondContact O-N 3.37Å; R197-S200 PolarHBondContact O-N 2.86Å; R197-E201 VanDerWaalsContact CG-OE1 3.31Å; R197-E201 WeakPolarHBondContact CG-OE1 3.18Å; R197-E201 IonicContact CZ-OE1 2.76Å; R197-E201 IonicContact NH1-OE1 2.7Å; R197-E201 PolarHBondContact NH1-OE1 3.26Å; R197-E201 IonicContact NH1-OE2 3.38Å; R197-E201 PolarHBondContact NH1-OE2 2.79Å; R197-E201 WeakPolarHBondContact O-CG 3.34Å; R197-E201 PolarHBondContact O-N 3.08Å; R197-Y250 PolarHBondContact NH1-OH 3.01Å; R197-Y250 PolarHBondContact NH2-OH 2.9Å
198M98.9Very high98.7Very high5 Ų541.7 Ų41.73%0.02522%0.221CC..Hα-helixtrans-57-50.9178.3-73.7173.358.700111.6P186 A189 E194 A195 S200 E201 V202 Y250 K253 I254P186-M198 HydrophobicContact CB-CB 4.37Å; P186-M198 HydrophobicContact CB-CE 4.1Å; A189-M198 HydrophobicContact CB-SD 3.7Å; E194-M198 WeakPolarHBondContact O-CB 3.5Å; E194-M198 WeakPolarHBondContact O-CG 3.33Å; E194-M198 PolarHBondContact O-N 3.23Å; A195-M198 PolarHBondContact O-N 2.78Å; M198-S200 PolarHBondContact O-N 3.28Å; M198-E201 PolarHBondContact O-N 2.62Å; M198-V202 VanDerWaalsContact O-CG2 3.29Å; M198-V202 WeakPolarHBondContact O-CG2 3.49Å; M198-V202 PolarHBondContact O-N 2.86Å; M198-V202 VanDerWaalsContact O-N 3.11Å; M198-Y250 HydrophobicContact CB-CD2 4.08Å; M198-Y250 HydrophobicContact CB-CE2 3.97Å; M198-Y250 HydrophobicContact CB-CG 4.5Å; M198-Y250 HydrophobicContact CE-CD1 3.88Å; M198-Y250 HydrophobicContact CE-CG 3.92Å; M198-Y250 HydrophobicContact CG-CD1 4.01Å; M198-Y250 HydrophobicContact CG-CD2 4.16Å; M198-Y250 HydrophobicContact CG-CE1 3.74Å; M198-Y250 HydrophobicContact CG-CE2 3.91Å; M198-Y250 HydrophobicContact CG-CG 4.24Å; M198-Y250 HydrophobicContact SD-CD1 4.39Å; M198-Y250 HydrophobicContact SD-CE1 4.48Å; M198-K253 HydrophobicContact CE-CB 3.61Å; M198-K253 HydrophobicContact CE-CD 4.33Å; M198-I254 HydrophobicContact CB-CD1 4.21Å; M198-I254 HydrophobicContact CE-CD1 4.12Å; M198-I254 HydrophobicContact CE-CG1 3.63Å
199G98.8Very high98.7Very high0 Ų040.3 Ų40.30%021%0.207CC..Hα-helixtrans-61.1-42178.300000113.4A195 M196 R197 V202 Y203A195-G199 PolarHBondContact O-N 3.25Å; M196-G199 PolarHBondContact O-N 3.02Å; R197-G199 PolarHBondContact O-N 3.37Å; G199-V202 PolarHBondContact O-N 2.76Å; G199-Y203 WeakPolarHBondContact O-CB 3.45Å; G199-Y203 PolarHBondContact O-N 2.81Å
200S98.7Very high98.7Very high38 Ų3840 Ų4027%0.26620%0.204SC..Hα-helixtrans-63.7-44.5178.2-171.10000112.4M196 R197 M198 Y203 H204M196-S200 VanDerWaalsContact O-CB 3.31Å; M196-S200 WeakPolarHBondContact O-CB 3.02Å; M196-S200 PolarHBondContact O-N 3.44Å; R197-S200 PolarHBondContact O-N 2.86Å; M198-S200 PolarHBondContact O-N 3.28Å; S200-Y203 PolarHBondContact O-N 3.29Å; S200-H204 PolarHBondContact O-CD2 3.11Å; S200-H204 PolarHBondContact O-N 3.41Å
201E98.9Very high98.7Very high70 Ų7040.2 Ų40.233%0.32719%0.194SC..Hα-helixtrans-65.4-42.7178.8-72.8173-166.200111.8R197 M198 Y203 H204 N205 Y250R197-E201 VanDerWaalsContact CG-OE1 3.31Å; R197-E201 WeakPolarHBondContact CG-OE1 3.18Å; R197-E201 IonicContact CZ-OE1 2.76Å; R197-E201 IonicContact NH1-OE1 2.7Å; R197-E201 PolarHBondContact NH1-OE1 3.26Å; R197-E201 IonicContact NH1-OE2 3.38Å; R197-E201 PolarHBondContact NH1-OE2 2.79Å; R197-E201 WeakPolarHBondContact O-CG 3.34Å; R197-E201 PolarHBondContact O-N 3.08Å; M198-E201 PolarHBondContact O-N 2.62Å; E201-Y203 VanDerWaalsContact C-N 3.34Å; E201-Y203 PolarHBondContact O-N 2.81Å; E201-H204 PolarHBondContact O-N 3.01Å; E201-N205 PolarHBondContact O-N 3.29Å; E201-Y250 HydrophobicContact CB-CE2 4.23Å; E201-Y250 WeakPolarHBondContact OE2-CE2 3.29Å; E201-Y250 VanDerWaalsContact OE2-CZ 3.31Å; E201-Y250 PolarHBondContact OE2-OH 3.45Å
202V98.9Very high98.6Very high0 Ų045 Ų450%022%0.222CC..Hα-helixtrans-62.9-41.7174-177.80000111.2L184 M198 G199 H204 N205 L206 A244 I245 S248 Y250 I254L184-V202 HydrophobicContact CD1-CB 3.64Å; L184-V202 HydrophobicContact CD1-CG1 3.42Å; L184-V202 VanDerWaalsContact CD1-CG1 3.42Å; L184-V202 HydrophobicContact CD2-CG1 3.97Å; L184-V202 HydrophobicContact CG-CG1 4.35Å; M198-V202 VanDerWaalsContact O-CG2 3.29Å; M198-V202 WeakPolarHBondContact O-CG2 3.49Å; M198-V202 PolarHBondContact O-N 2.86Å; M198-V202 VanDerWaalsContact O-N 3.11Å; G199-V202 PolarHBondContact O-N 2.76Å; V202-H204 VanDerWaalsContact C-N 3.33Å; V202-H204 PolarHBondContact O-N 3.41Å; V202-N205 PolarHBondContact O-N 3.12Å; V202-L206 VanDerWaalsContact O-CB 3.23Å; V202-L206 WeakPolarHBondContact O-CB 3.46Å; V202-L206 PolarHBondContact O-N 2.97Å; V202-A244 HydrophobicContact CG1-CB 3.84Å; V202-I245 HydrophobicContact CG1-CG1 3.98Å; V202-S248 WeakPolarHBondContact CA-OG 3.32Å; V202-Y250 HydrophobicContact CG2-CD2 3.73Å; V202-Y250 HydrophobicContact CG2-CE2 4.43Å; V202-I254 HydrophobicContact CB-CD1 4.46Å; V202-I254 HydrophobicContact CG2-CD1 3.38Å
203Y98.8Very high98.5Very high17 Ų1750.8 Ų50.87%0.06724%0.244CC..Hα-helixtrans-58.7-42.7176.7178.5-107.5000112.1V166 G199 S200 E201 L206 K207 G225 F227 A416 P417 C418V166-Y203 HydrophobicContact CB-CD2 4.06Å; V166-Y203 HydrophobicContact CG1-CD2 3.72Å; G199-Y203 WeakPolarHBondContact O-CB 3.45Å; G199-Y203 PolarHBondContact O-N 2.81Å; S200-Y203 PolarHBondContact O-N 3.29Å; E201-Y203 VanDerWaalsContact C-N 3.34Å; E201-Y203 PolarHBondContact O-N 2.81Å; Y203-L206 PolarHBondContact O-N 3.38Å; Y203-K207 PolarHBondContact O-N 2.83Å; Y203-K207 VanDerWaalsContact O-N 3.08Å; Y203-G225 PolarHBondContact OH-O 2.99Å; Y203-F227 HydrophobicContact CD1-CZ 4.47Å; Y203-F227 HydrophobicContact CD2-CD2 4.31Å; Y203-F227 AromaticContact CD2-CE2 3.55Å; Y203-F227 HydrophobicContact CD2-CE2 3.55Å; Y203-F227 HydrophobicContact CD2-CZ 4.04Å; Y203-F227 HydrophobicContact CE1-CE2 4.44Å; Y203-F227 AromaticContact CE1-CZ 3.94Å; Y203-F227 HydrophobicContact CE1-CZ 3.94Å; Y203-F227 AromaticContact CE2-CD2 3.88Å; Y203-F227 HydrophobicContact CE2-CD2 3.88Å; Y203-F227 HydrophobicContact CE2-CE1 4.25Å; Y203-F227 AromaticContact CE2-CE2 3.24Å; Y203-F227 HydrophobicContact CE2-CE2 3.24Å; Y203-F227 AromaticContact CE2-CZ 3.43Å; Y203-F227 HydrophobicContact CE2-CZ 3.43Å; Y203-F227 VanDerWaalsContact CE2-CZ 3.43Å; Y203-F227 HydrophobicContact CG-CE2 4.26Å; Y203-F227 AromaticContact CZ-CE2 3.74Å; Y203-F227 AromaticContact CZ-CZ 3.37Å; Y203-F227 WeakPolarHBondContact O-CE2 3.49Å; Y203-A416 HydrophobicContact CD2-CB 4.39Å; Y203-A416 HydrophobicContact CE2-CB 3.9Å; Y203-P417 HydrophobicContact CD1-CG 4.01Å; Y203-P417 HydrophobicContact CD2-CG 4.48Å; Y203-P417 HydrophobicContact CG-CG 3.83Å; Y203-C418 HydrophobicContact CE1-CB 4.19Å; Y203-C418 PolarHBondContact OH-SG 3.31Å
204H98.7Very high98.4Very high118 Ų11848.5 Ų48.555%0.54623%0.232SC..Hα-helixtrans-68.2-40.6175.1-75.1-63.4000113.1S200 E201 V202 K207 G208S200-H204 PolarHBondContact O-CD2 3.11Å; S200-H204 PolarHBondContact O-N 3.41Å; E201-H204 PolarHBondContact O-N 3.01Å; V202-H204 VanDerWaalsContact C-N 3.33Å; V202-H204 PolarHBondContact O-N 3.41Å; H204-K207 WeakPolarHBondContact O-CB 3.39Å; H204-K207 PolarHBondContact O-N 2.99Å; H204-G208 PolarHBondContact O-N 2.69Å
205N98.8Very high98.2Very high44 Ų4447.4 Ų47.424%0.23524%0.235CC..Hα-helixtrans-65.2-39.6175.4-86.2-36.7000112.1E201 V202 K207 G208 C209 K247 S248E201-N205 PolarHBondContact O-N 3.29Å; V202-N205 PolarHBondContact O-N 3.12Å; N205-K207 VanDerWaalsContact C-N 3.34Å; N205-K207 PolarHBondContact O-N 3.15Å; N205-G208 CarbonylContact O-C 3.6Å; N205-G208 WeakPolarHBondContact O-CA 3.46Å; N205-G208 PolarHBondContact O-N 3.06Å; N205-C209 PolarHBondContact O-N 3.18Å; N205-C209 PolarHBondContact O-SG 3.07Å; N205-K247 HydrophobicContact CB-CD 4.28Å; N205-S248 PolarHBondContact ND2-OG 2.85Å
206L98.8Very high98Very high0 Ų052.4 Ų52.40%026%0.261CS..Hα-helixtrans-58.7-44.4174.3177.362.2000111.3V166 I167 V202 Y203 G208 C209 I210 F227 L240 L241 A244V166-L206 HydrophobicContact CB-CD2 3.79Å; V166-L206 HydrophobicContact CG2-CD2 3.78Å; I167-L206 HydrophobicContact CD1-CD1 4.35Å; I167-L206 HydrophobicContact CD1-CD2 4.4Å; I167-L206 HydrophobicContact CG1-CD2 3.95Å; V202-L206 VanDerWaalsContact O-CB 3.23Å; V202-L206 WeakPolarHBondContact O-CB 3.46Å; V202-L206 PolarHBondContact O-N 2.97Å; Y203-L206 PolarHBondContact O-N 3.38Å; L206-G208 PolarHBondContact O-N 3.36Å; L206-C209 PolarHBondContact O-N 2.87Å; L206-C209 VanDerWaalsContact O-N 3.17Å; L206-I210 HydrophobicContact CD1-CD1 3.93Å; L206-I210 HydrophobicContact CD1-CG1 4.12Å; L206-I210 HydrophobicContact CG-CD1 3.86Å; L206-I210 HydrophobicContact CG-CG1 4.45Å; L206-I210 WeakPolarHBondContact O-CB 3.36Å; L206-I210 WeakPolarHBondContact O-CG1 3.44Å; L206-I210 PolarHBondContact O-N 2.85Å; L206-F227 HydrophobicContact CB-CE2 4.36Å; L206-F227 HydrophobicContact CD2-CD2 3.82Å; L206-F227 HydrophobicContact CD2-CE2 4.2Å; L206-F227 HydrophobicContact CG-CD2 3.92Å; L206-F227 HydrophobicContact CG-CE2 4.17Å; L206-L240 HydrophobicContact CD1-CB 3.89Å; L206-L241 HydrophobicContact CD1-CD2 4.15Å; L206-L241 HydrophobicContact CD2-CD2 3.73Å; L206-A244 HydrophobicContact CB-CB 3.76Å; L206-A244 HydrophobicContact CD1-CB 4.15Å
207K98.6Very high97.8Very high94 Ų9458.5 Ų58.541%0.40930%0.295SS..Hα-helixtrans-53.8-43.9172.3-165.6173.6-179.7171.30111.7Y203 H204 N205 K211 T219 F227Y203-K207 PolarHBondContact O-N 2.83Å; Y203-K207 VanDerWaalsContact O-N 3.08Å; H204-K207 WeakPolarHBondContact O-CB 3.39Å; H204-K207 PolarHBondContact O-N 2.99Å; N205-K207 VanDerWaalsContact C-N 3.34Å; N205-K207 PolarHBondContact O-N 3.15Å; K207-K211 VanDerWaalsContact O-CB 3.28Å; K207-K211 WeakPolarHBondContact O-CB 3.44Å; K207-K211 PolarHBondContact O-N 2.95Å; K207-T219 HydrophobicContact CG-CG2 3.74Å; K207-F227 HydrophobicContact CB-CE1 3.95Å; K207-F227 HydrophobicContact CB-CE2 3.88Å; K207-F227 HydrophobicContact CB-CZ 3.38Å; K207-F227 HydrophobicContact CD-CE1 3.89Å; K207-F227 HydrophobicContact CD-CZ 3.93Å; K207-F227 HydrophobicContact CG-CE1 3.67Å; K207-F227 HydrophobicContact CG-CZ 3.65Å
208G98.4Very high97.7Very high26 Ų2654.7 Ų54.727%0.26828%0.283SS..Hα-helixtrans-62.1-48.9176.500000112.4H204 N205 L206 I210 K211 T212H204-G208 PolarHBondContact O-N 2.69Å; N205-G208 CarbonylContact O-C 3.6Å; N205-G208 WeakPolarHBondContact O-CA 3.46Å; N205-G208 PolarHBondContact O-N 3.06Å; L206-G208 PolarHBondContact O-N 3.36Å; G208-I210 PolarHBondContact O-N 2.94Å; G208-K211 PolarHBondContact O-N 2.98Å; G208-T212 PolarHBondContact O-N 3.33Å; G208-T212 PolarHBondContact O-OG1 3.43Å
209C98.3Very high97.6Very high1 Ų155.4 Ų55.41%0.00729%0.288CS..Hα-helixtrans-59.8-46.3178-63.70000111.8N205 L206 T212 R213 L240 E243N205-C209 PolarHBondContact O-N 3.18Å; N205-C209 PolarHBondContact O-SG 3.07Å; L206-C209 PolarHBondContact O-N 2.87Å; L206-C209 VanDerWaalsContact O-N 3.17Å; C209-T212 PolarHBondContact O-N 3.38Å; C209-R213 WeakPolarHBondContact O-CG 3.41Å; C209-R213 PolarHBondContact O-N 2.97Å; C209-L240 HydrophobicContact CB-CD2 4.08Å; C209-E243 PolarHBondContact SG-OE1 2.88Å
210I98.4Very high97.5Very high0 Ų058.3 Ų58.30%031%0.311CS..Hα-helixtrans-61-48176.6-70.4170.6000110.7L206 G208 T212 R213 Y214 A218 T219 F227 P229 L240L206-I210 HydrophobicContact CD1-CD1 3.93Å; L206-I210 HydrophobicContact CD1-CG1 4.12Å; L206-I210 HydrophobicContact CG-CD1 3.86Å; L206-I210 HydrophobicContact CG-CG1 4.45Å; L206-I210 WeakPolarHBondContact O-CB 3.36Å; L206-I210 WeakPolarHBondContact O-CG1 3.44Å; L206-I210 PolarHBondContact O-N 2.85Å; G208-I210 PolarHBondContact O-N 2.94Å; I210-T212 VanDerWaalsContact C-N 3.3Å; I210-T212 PolarHBondContact O-N 3.33Å; I210-R213 PolarHBondContact O-N 3.46Å; I210-Y214 HydrophobicContact CG2-CD2 4.4Å; I210-Y214 PolarHBondContact O-N 3.45Å; I210-A218 HydrophobicContact CG2-CB 3.62Å; I210-A218 VanDerWaalsContact CG2-O 3.28Å; I210-A218 WeakPolarHBondContact CG2-O 3.25Å; I210-T219 HydrophobicContact CG2-CG2 4.14Å; I210-F227 HydrophobicContact CD1-CB 3.5Å; I210-F227 HydrophobicContact CD1-CD2 3.74Å; I210-F227 HydrophobicContact CD1-CG 3.75Å; I210-P229 HydrophobicContact CD1-CG 4.18Å; I210-P229 HydrophobicContact CG2-CB 4.05Å; I210-L240 HydrophobicContact CD1-CD1 4.45Å; I210-L240 HydrophobicContact CG1-CD1 3.83Å; I210-L240 HydrophobicContact CG1-CD2 4.04Å
211K97.8Very high97.4Very high115 Ų11558.3 Ų58.350%0.531%0.31SS..Hα-helixtrans-58.4-42.4178.5-179.2176.2175.4-178.30112K207 G208 G215 L216 T219K207-K211 VanDerWaalsContact O-CB 3.28Å; K207-K211 WeakPolarHBondContact O-CB 3.44Å; K207-K211 PolarHBondContact O-N 2.95Å; G208-K211 PolarHBondContact O-N 2.98Å; K211-G215 WeakPolarHBondContact CA-O 3.46Å; K211-G215 CarbonylContact O-C 3.47Å; K211-G215 WeakPolarHBondContact O-CA 3.4Å; K211-G215 PolarHBondContact O-N 3.08Å; K211-L216 HydrophobicContact CD-CD1 4.06Å; K211-T219 HydrophobicContact CB-CG2 3.88Å
212T97.6Very high97.3Very high123 Ų12355.8 Ų55.876%0.75530%0.303SS*.Hα-helixtrans-66.5-41.6179.6-67.30000112.2G208 C209 I210G208-T212 PolarHBondContact O-N 3.33Å; G208-T212 PolarHBondContact O-OG1 3.43Å; C209-T212 PolarHBondContact O-N 3.38Å; I210-T212 VanDerWaalsContact C-N 3.3Å; I210-T212 PolarHBondContact O-N 3.33Å
213R96.6Very high97.1Very high123 Ų12358.8 Ų58.846%0.46432%0.318SS..Hα-helixtrans-83.3-38.1-175.6-68.7-174.8-178.1-152.8-1.7113.9C209 I210 E243C209-R213 WeakPolarHBondContact O-CG 3.41Å; C209-R213 PolarHBondContact O-N 2.97Å; I210-R213 PolarHBondContact O-N 3.46Å; R213-E243 IonicContact CZ-OE2 3.73Å; R213-E243 IonicContact NE-OE2 2.67Å; R213-E243 PolarHBondContact NE-OE2 3.33Å; R213-E243 IonicContact NH2-OE2 2.77Å; R213-E243 PolarHBondContact NH2-OE2 2.93Å
214Y95.9Very high97Very high77 Ų7758.1 Ų58.130%0.30232%0.316SS..Hα-helixtrans-1241.3-168.1-52.6-77.1000113.9I210 I231 E236 L240I210-Y214 HydrophobicContact CG2-CD2 4.4Å; I210-Y214 PolarHBondContact O-N 3.45Å; Y214-I231 HydrophobicContact CD1-CG2 4.14Å; Y214-I231 HydrophobicContact CE1-CG2 3.48Å; Y214-I231 VanDerWaalsContact CE1-CG2 3.48Å; Y214-I231 HydrophobicContact CE2-CG2 4Å; Y214-I231 VanDerWaalsContact CZ-CG2 3.4Å; Y214-E236 PolarHBondContact OH-OE2 3.45Å; Y214-L240 HydrophobicContact CE2-CD1 3.88Å; Y214-L240 HydrophobicContact CE2-CD2 4.13Å; Y214-L240 HydrophobicContact CE2-CG 4.3Å
215G95.5Very high96.9Very high31 Ų3152.6 Ų52.632%0.3229%0.291SS..  trans88.5173.9178.800000114.2K211 D217 A218K211-G215 WeakPolarHBondContact CA-O 3.46Å; K211-G215 CarbonylContact O-C 3.47Å; K211-G215 WeakPolarHBondContact O-CA 3.4Å; K211-G215 PolarHBondContact O-N 3.08Å; G215-D217 PolarHBondContact O-N 3.14Å; G215-A218 PolarHBondContact O-N 2.92Å
216L94.9Very high96.9Very high105 Ų10550.5 Ų50.555%0.5528%0.279SS..G310 helixtrans-62.6-41.6-172.9-179.562.8000112.9K211 A218 T219K211-L216 HydrophobicContact CD-CD1 4.06Å; L216-A218 PolarHBondContact O-N 3.4Å; L216-T219 WeakPolarHBondContact O-CB 3.21Å; L216-T219 PolarHBondContact O-N 3.14Å; L216-T219 PolarHBondContact O-OG1 3.46Å
217D94.3Very high96.9Very high149 Ų14950.5 Ų50.580%0.79728%0.28SS*.G310 helixtrans-66.7-23.8-175-59.8-28.1000112.4G215 T219 A220G215-D217 PolarHBondContact O-N 3.14Å; D217-T219 PolarHBondContact O-N 3.24Å; D217-T219 VanDerWaalsContact O-N 3.12Å; D217-A220 PolarHBondContact O-N 2.86Å
218A95.4Very high96.8Very high13 Ų1347.1 Ų47.111%0.10727%0.269CS..G310 helixtrans-68.1-7.1174.700000113.5I210 G215 L216 P229I210-A218 HydrophobicContact CG2-CB 3.62Å; I210-A218 VanDerWaalsContact CG2-O 3.28Å; I210-A218 WeakPolarHBondContact CG2-O 3.25Å; G215-A218 PolarHBondContact O-N 2.92Å; L216-A218 PolarHBondContact O-N 3.4Å; A218-P229 HydrophobicContact CB-CB 4.2Å
219T96.9Very high96.7Very high20 Ų2045.9 Ų45.912%0.12326%0.256CS..G310 helixtrans-929.5176.669.60000114.3K207 I210 K211 L216 D217 F227K207-T219 HydrophobicContact CG-CG2 3.74Å; I210-T219 HydrophobicContact CG2-CG2 4.14Å; K211-T219 HydrophobicContact CB-CG2 3.88Å; L216-T219 WeakPolarHBondContact O-CB 3.21Å; L216-T219 PolarHBondContact O-N 3.14Å; L216-T219 PolarHBondContact O-OG1 3.46Å; D217-T219 PolarHBondContact O-N 3.24Å; D217-T219 VanDerWaalsContact O-N 3.12Å; T219-F227 WeakPolarHBondContact O-CD1 3.39Å
220A96.9Very high96.5Very high60 Ų6050.6 Ų50.650%0.49628%0.281SS..  trans-60.7156.4164.800000110.5D217 F227 A228D217-A220 PolarHBondContact O-N 2.86Å; A220-F227 CarbonylContact O-C 3.53Å; A220-F227 WeakPolarHBondContact O-CA 3.31Å; A220-A228 PolarHBondContact O-N 2.86Å
221V97.1Very high96.1Very high39 Ų3950.6 Ų50.624%0.23628%0.281CS..BIsolated β-bridgetrans-120.2149.8-176.6-59.40000111.6G225 G226 F227V221-G225 VanDerWaalsContact CG1-O 3.29Å; V221-G225 WeakPolarHBondContact CG1-O 3.16Å; V221-G226 CarbonylContact C-O 3.09Å; V221-G226 WeakPolarHBondContact CA-O 3.36Å; V221-G226 VanDerWaalsContact CB-O 3.29Å; V221-G226 WeakPolarHBondContact CB-O 3.37Å; V221-F227 HydrophobicContact CG1-CD1 3.83Å; V221-F227 HydrophobicContact CG1-CE1 4.06Å
222G96.4Very high95.4Very high17 Ų1748.5 Ų48.518%0.17528%0.279CS..  trans-83.2-168.1173.800000113.4H172 E224 G225 G226H172-G222 VanDerWaalsContact O-CA 3.29Å; H172-G222 WeakPolarHBondContact O-CA 3.35Å; G222-E224 PolarHBondContact O-N 2.87Å; G222-G225 PolarHBondContact O-N 3.1Å; G222-G225 VanDerWaalsContact O-N 3.08Å; G222-G226 PolarHBondContact N-O 3.04Å
223D95.1Very high95.2Very high62 Ų6245.9 Ų45.933%0.33226%0.261SS..THydrogen-bonded Turntrans-56.2-26-175.6-79.42.1000113.7R29 H172 R422R29-D223 WeakPolarHBondContact CD-OD2 3.34Å; H172-D223 HydrophobicContact CB-CB 4.42Å; H172-D223 PolarHBondContact O-N 3.17Å; D223-R422 PolarHBondContact O-NH2 3.45Å
224E96.1Very high95.2Very high4 Ų440.3 Ų40.32%0.01924%0.241CC..THydrogen-bonded Turntrans-107.68-174.5-58.1-172.6147.400113.5N165 H172 E181 G222 G226 H390 A416N165-E224 HydrophobicContact CB-CB 4.41Å; N165-E224 PolarHBondContact ND2-OE2 3.39Å; H172-E224 IonicContact CE1-OE1 3.06Å; H172-E224 PolarHBondContact CE1-OE1 3.44Å; H172-E224 IonicContact ND1-OE1 3.92Å; H172-E224 IonicContact ND1-OE2 3.18Å; E181-E224 VanDerWaalsContact OE1-CD 3.32Å; G222-E224 PolarHBondContact O-N 2.87Å; E224-G226 VanDerWaalsContact C-N 3.26Å; E224-G226 PolarHBondContact O-N 2.81Å; E224-H390 IonicContact OE1-CE1 2.71Å; E224-H390 PolarHBondContact OE1-CE1 2.84Å; E224-H390 IonicContact OE1-NE2 2.83Å; E224-H390 PolarHBondContact OE1-NE2 3.5Å; E224-A416 PolarHBondContact O-N 3.42Å
225G97.5Very high95.2Very high1 Ų140.1 Ų40.11%0.0124%0.241CC..SBendtrans81.1-1.5179.200000114.4Y203 V221 G222 A416 C418Y203-G225 PolarHBondContact OH-O 2.99Å; V221-G225 VanDerWaalsContact CG1-O 3.29Å; V221-G225 WeakPolarHBondContact CG1-O 3.16Å; G222-G225 PolarHBondContact O-N 3.1Å; G222-G225 VanDerWaalsContact O-N 3.08Å; G225-A416 VanDerWaalsContact O-CB 3.27Å; G225-A416 WeakPolarHBondContact O-CB 3.29Å; G225-C418 PolarHBondContact O-SG 2.99Å
226G98.3Very high95.2Very high0 Ų041.6 Ų41.60%024%0.24CC..  trans-71.4149.1170.800000111.3N165 V166 N168 V221 G222 E224N165-G226 VanDerWaalsContact O-CA 3.27Å; N165-G226 WeakPolarHBondContact O-CA 3.15Å; N165-G226 PolarHBondContact O-N 3.02Å; V166-G226 VanDerWaalsContact C-CA 3.48Å; V166-G226 CarbonylContact O-C 3.57Å; V166-G226 WeakPolarHBondContact O-CA 3.34Å; N168-G226 VanDerWaalsContact OD1-CA 3.27Å; N168-G226 WeakPolarHBondContact OD1-CA 3.38Å; N168-G226 PolarHBondContact OD1-N 3.27Å; N168-G226 PolarHBondContact OD1-O 2.89Å; V221-G226 CarbonylContact C-O 3.09Å; V221-G226 WeakPolarHBondContact CA-O 3.36Å; V221-G226 VanDerWaalsContact CB-O 3.29Å; V221-G226 WeakPolarHBondContact CB-O 3.37Å; G222-G226 PolarHBondContact N-O 3.04Å; E224-G226 VanDerWaalsContact C-N 3.26Å; E224-G226 PolarHBondContact O-N 2.81Å
227F98.5Very high95.4Very high1 Ų136.6 Ų36.60%0.00421%0.214CC..BIsolated β-bridgetrans-63.8146177.8-60.3-65.8000111.4V166 I167 N168 Y203 L206 K207 I210 T219 A220 V221 P229V166-F227 WeakPolarHBondContact O-CD2 3.42Å; V166-F227 PolarHBondContact O-N 3.08Å; I167-F227 CarbonylContact C-O 3.55Å; I167-F227 VanDerWaalsContact CA-O 3.26Å; I167-F227 WeakPolarHBondContact CA-O 2.92Å; N168-F227 PolarHBondContact N-O 2.91Å; Y203-F227 HydrophobicContact CD1-CZ 4.47Å; Y203-F227 HydrophobicContact CD2-CD2 4.31Å; Y203-F227 AromaticContact CD2-CE2 3.55Å; Y203-F227 HydrophobicContact CD2-CE2 3.55Å; Y203-F227 HydrophobicContact CD2-CZ 4.04Å; Y203-F227 HydrophobicContact CE1-CE2 4.44Å; Y203-F227 AromaticContact CE1-CZ 3.94Å; Y203-F227 HydrophobicContact CE1-CZ 3.94Å; Y203-F227 AromaticContact CE2-CD2 3.88Å; Y203-F227 HydrophobicContact CE2-CD2 3.88Å; Y203-F227 HydrophobicContact CE2-CE1 4.25Å; Y203-F227 AromaticContact CE2-CE2 3.24Å; Y203-F227 HydrophobicContact CE2-CE2 3.24Å; Y203-F227 AromaticContact CE2-CZ 3.43Å; Y203-F227 HydrophobicContact CE2-CZ 3.43Å; Y203-F227 VanDerWaalsContact CE2-CZ 3.43Å; Y203-F227 HydrophobicContact CG-CE2 4.26Å; Y203-F227 AromaticContact CZ-CE2 3.74Å; Y203-F227 AromaticContact CZ-CZ 3.37Å; Y203-F227 WeakPolarHBondContact O-CE2 3.49Å; L206-F227 HydrophobicContact CB-CE2 4.36Å; L206-F227 HydrophobicContact CD2-CD2 3.82Å; L206-F227 HydrophobicContact CD2-CE2 4.2Å; L206-F227 HydrophobicContact CG-CD2 3.92Å; L206-F227 HydrophobicContact CG-CE2 4.17Å; K207-F227 HydrophobicContact CB-CE1 3.95Å; K207-F227 HydrophobicContact CB-CE2 3.88Å; K207-F227 HydrophobicContact CB-CZ 3.38Å; K207-F227 HydrophobicContact CD-CE1 3.89Å; K207-F227 HydrophobicContact CD-CZ 3.93Å; K207-F227 HydrophobicContact CG-CE1 3.67Å; K207-F227 HydrophobicContact CG-CZ 3.65Å; I210-F227 HydrophobicContact CD1-CB 3.5Å; I210-F227 HydrophobicContact CD1-CD2 3.74Å; I210-F227 HydrophobicContact CD1-CG 3.75Å; T219-F227 WeakPolarHBondContact O-CD1 3.39Å; A220-F227 CarbonylContact O-C 3.53Å; A220-F227 WeakPolarHBondContact O-CA 3.31Å; V221-F227 HydrophobicContact CG1-CD1 3.83Å; V221-F227 HydrophobicContact CG1-CE1 4.06Å; F227-P229 VanDerWaalsContact O-CD 3.22Å; F227-P229 WeakPolarHBondContact O-CD 3.44Å
228A97.3Very high95.6Very high22 Ų2229.5 Ų29.518%0.18218%0.176CC..  trans-118.257.7-179.500000112A173 A220A173-A228 HydrophobicContact CB-CB 3.76Å; A220-A228 PolarHBondContact O-N 2.86Å
229P96.9Very high95.7Very high0 Ų030.9 Ų30.90%018%0.182CC..  trans-63.5151177.129.4-34.8000110.9I167 N175 I210 A218 F227 I231I167-P229 HydrophobicContact CG2-CG 4.42Å; N175-P229 WeakPolarHBondContact CB-O 3.36Å; N175-P229 PolarHBondContact ND2-O 2.68Å; I210-P229 HydrophobicContact CD1-CG 4.18Å; I210-P229 HydrophobicContact CG2-CB 4.05Å; A218-P229 HydrophobicContact CB-CB 4.2Å; F227-P229 VanDerWaalsContact O-CD 3.22Å; F227-P229 WeakPolarHBondContact O-CD 3.44Å; P229-I231 HydrophobicContact CB-CD1 4.44Å; P229-I231 HydrophobicContact CB-CG1 4.45Å; P229-I231 HydrophobicContact CB-CG2 4.47Å; P229-I231 HydrophobicContact CG-CD1 3.69Å; P229-I231 HydrophobicContact CG-CG1 3.99Å; P229-I231 PolarHBondContact O-N 2.84Å
230N92.8Very high95.8Very high101 Ų10130 Ų3054%0.5418%0.176SC..  trans-82.566.2179.4-170.329.2000111.9K176K176-N230 WeakPolarHBondContact CG-OD1 3.4Å
231I91.3Very high95.9Very high0 Ų027.1 Ų27.10%015%0.152CC..  trans-111.4114.7177.855.4-173000109.4L177 Y214 P229 E236 A237 L240L177-I231 WeakPolarHBondContact CB-O 3.22Å; L177-I231 HydrophobicContact CD2-CG1 4.41Å; Y214-I231 HydrophobicContact CD1-CG2 4.14Å; Y214-I231 HydrophobicContact CE1-CG2 3.48Å; Y214-I231 VanDerWaalsContact CE1-CG2 3.48Å; Y214-I231 HydrophobicContact CE2-CG2 4Å; Y214-I231 VanDerWaalsContact CZ-CG2 3.4Å; P229-I231 HydrophobicContact CB-CD1 4.44Å; P229-I231 HydrophobicContact CB-CG1 4.45Å; P229-I231 HydrophobicContact CB-CG2 4.47Å; P229-I231 HydrophobicContact CG-CD1 3.69Å; P229-I231 HydrophobicContact CG-CG1 3.99Å; P229-I231 PolarHBondContact O-N 2.84Å; I231-E236 HydrophobicContact CB-CB 4.22Å; I231-E236 HydrophobicContact CD1-CB 4.33Å; I231-E236 HydrophobicContact CG2-CB 4.32Å; I231-A237 HydrophobicContact CD1-CB 3.77Å; I231-L240 HydrophobicContact CD1-CD1 3.87Å
232P83.3Confident95.9Very high70 Ų7030.3 Ų30.346%0.45516%0.163SC..  trans-77.1-30.5-179.529.3-32.8000112.5K176 P234K176-P232 HydrophobicContact CB-CB 4.12Å; P232-P234 WeakPolarHBondContact O-CD 3.33Å
233D92.5Very high96Very high68 Ų6832.7 Ų32.736%0.36417%0.169SC..  trans-85.8118.9-178.5-175-1.7000111.2K235 E236D233-K235 PolarHBondContact O-N 3.36Å; D233-K235 VanDerWaalsContact O-N 3.12Å; D233-K235 VanDerWaalsContact OD1-CB 3.25Å; D233-K235 WeakPolarHBondContact OD1-CB 3.37Å; D233-K235 PolarHBondContact OD1-N 3.29Å; D233-K235 WeakPolarHBondContact OD2-CB 3.49Å; D233-E236 HydrophobicContact CB-CG 4.3Å; D233-E236 WeakPolarHBondContact O-CB 3.19Å; D233-E236 PolarHBondContact O-N 3.32Å
234P95.5Very high96.2Very high7 Ų729.7 Ų29.75%0.04515%0.154CC..Hα-helixtrans-54.3-27.6172.7-26.635.9000114.3L177 M179 F182 P232 E236 A237 L238 Y302L177-P234 HydrophobicContact CD1-CB 4.39Å; L177-P234 HydrophobicContact CD1-CG 4.11Å; M179-P234 HydrophobicContact CE-CB 4.31Å; M179-P234 HydrophobicContact CE-CG 3.93Å; M179-P234 HydrophobicContact CG-CB 4.41Å; M179-P234 HydrophobicContact CG-CG 3.98Å; M179-P234 HydrophobicContact SD-CB 3.61Å; M179-P234 HydrophobicContact SD-CG 3.64Å; F182-P234 HydrophobicContact CE1-CB 4.16Å; F182-P234 HydrophobicContact CZ-CB 3.86Å; P232-P234 WeakPolarHBondContact O-CD 3.33Å; P234-E236 VanDerWaalsContact C-N 3.28Å; P234-E236 PolarHBondContact O-N 2.71Å; P234-A237 WeakPolarHBondContact O-CB 3.38Å; P234-A237 PolarHBondContact O-N 2.84Å; P234-L238 WeakPolarHBondContact O-CG 3.13Å; P234-L238 PolarHBondContact O-N 3.35Å; P234-L238 VanDerWaalsContact O-N 3.11Å; P234-Y302 HydrophobicContact CB-CE2 4.28Å; P234-Y302 WeakPolarHBondContact CB-OH 3.46Å
235K96.7Very high96.3Very high72 Ų7229.9 Ų29.931%0.31315%0.154SC..Hα-helixtrans-61-38.5176.3-170-173.1169.6-67.20111.8D233 A237 L238 D239 Y302 Y306D233-K235 PolarHBondContact O-N 3.36Å; D233-K235 VanDerWaalsContact O-N 3.12Å; D233-K235 VanDerWaalsContact OD1-CB 3.25Å; D233-K235 WeakPolarHBondContact OD1-CB 3.37Å; D233-K235 PolarHBondContact OD1-N 3.29Å; D233-K235 WeakPolarHBondContact OD2-CB 3.49Å; K235-A237 VanDerWaalsContact C-N 3.3Å; K235-A237 PolarHBondContact O-N 3.23Å; K235-L238 PolarHBondContact O-N 2.96Å; K235-D239 IonicContact NZ-OD1 3.07Å; K235-D239 IonicContact NZ-OD2 2.69Å; K235-D239 PolarHBondContact NZ-OD2 2.85Å; K235-D239 PolarHBondContact O-N 3.46Å; K235-Y302 HydrophobicContact CB-CE1 4.34Å; K235-Y306 HydrophobicContact CG-CE2 4.29Å; K235-Y306 WeakPolarHBondContact CG-OH 3.33Å; K235-Y306 PolarHBondContact NZ-OH 2.94Å
236E96.6Very high96.4Very high62 Ų6231.6 Ų31.629%0.2917%0.168SC..Hα-helixtrans-64.9-36.6177.5-70.5-172.3-122.300111.7Y214 I231 D233 P234 D239 L240Y214-E236 PolarHBondContact OH-OE2 3.45Å; I231-E236 HydrophobicContact CB-CB 4.22Å; I231-E236 HydrophobicContact CD1-CB 4.33Å; I231-E236 HydrophobicContact CG2-CB 4.32Å; D233-E236 HydrophobicContact CB-CG 4.3Å; D233-E236 WeakPolarHBondContact O-CB 3.19Å; D233-E236 PolarHBondContact O-N 3.32Å; P234-E236 VanDerWaalsContact C-N 3.28Å; P234-E236 PolarHBondContact O-N 2.71Å; E236-D239 PolarHBondContact O-N 3.34Å; E236-L240 WeakPolarHBondContact O-CG 3.34Å; E236-L240 PolarHBondContact O-N 2.77Å
237A97.9Very high96.4Very high0 Ų037.1 Ų37.10%019%0.193CC..Hα-helixtrans-63-43.9174.300000110.9I167 L177 F182 I231 P234 K235 L240 L241I167-A237 HydrophobicContact CD1-CB 3.97Å; I167-A237 HydrophobicContact CG2-CB 4.38Å; L177-A237 HydrophobicContact CD2-CB 4.34Å; F182-A237 HydrophobicContact CD1-CB 3.84Å; F182-A237 HydrophobicContact CD2-CB 4.04Å; F182-A237 HydrophobicContact CE1-CB 3.68Å; F182-A237 HydrophobicContact CE2-CB 3.96Å; F182-A237 HydrophobicContact CG-CB 4.02Å; F182-A237 HydrophobicContact CZ-CB 3.75Å; I231-A237 HydrophobicContact CD1-CB 3.77Å; P234-A237 WeakPolarHBondContact O-CB 3.38Å; P234-A237 PolarHBondContact O-N 2.84Å; K235-A237 VanDerWaalsContact C-N 3.3Å; K235-A237 PolarHBondContact O-N 3.23Å; A237-L240 WeakPolarHBondContact O-CB 3.42Å; A237-L240 PolarHBondContact O-N 3.13Å; A237-L241 WeakPolarHBondContact O-CG 3.33Å; A237-L241 PolarHBondContact O-N 2.82Å
238L98.6Very high96.4Very high0 Ų037.9 Ų37.90%020%0.198CC..Hα-helixtrans-65.8-38.6176.7-66.4168.6000112.7F182 P234 K235 L241 K242 I256 M258 Y302 Y306 I308F182-L238 HydrophobicContact CD1-CD2 3.84Å; F182-L238 HydrophobicContact CD1-CG 4.08Å; F182-L238 HydrophobicContact CE1-CD2 4.18Å; F182-L238 HydrophobicContact CE1-CG 3.99Å; P234-L238 WeakPolarHBondContact O-CG 3.13Å; P234-L238 PolarHBondContact O-N 3.35Å; P234-L238 VanDerWaalsContact O-N 3.11Å; K235-L238 PolarHBondContact O-N 2.96Å; L238-L241 PolarHBondContact O-N 2.88Å; L238-K242 WeakPolarHBondContact O-CB 3.05Å; L238-K242 PolarHBondContact O-N 2.78Å; L238-I256 HydrophobicContact CD2-CD1 4.32Å; L238-I256 HydrophobicContact CD2-CG2 3.83Å; L238-M258 HydrophobicContact CD1-SD 4.31Å; L238-M258 HydrophobicContact CD2-CG 4.49Å; L238-M258 HydrophobicContact CD2-SD 4.02Å; L238-Y302 HydrophobicContact CD1-CD1 3.81Å; L238-Y302 HydrophobicContact CD1-CD2 4.31Å; L238-Y302 HydrophobicContact CD1-CE1 4.34Å; L238-Y302 HydrophobicContact CD1-CG 3.81Å; L238-Y306 HydrophobicContact CB-CD1 3.69Å; L238-Y306 HydrophobicContact CB-CD2 3.9Å; L238-Y306 HydrophobicContact CB-CE1 3.56Å; L238-Y306 HydrophobicContact CB-CE2 3.78Å; L238-Y306 HydrophobicContact CB-CG 3.87Å; L238-Y306 HydrophobicContact CD1-CD2 3.6Å; L238-Y306 HydrophobicContact CD1-CE2 3.76Å; L238-Y306 HydrophobicContact CD1-CG 4.18Å; L238-Y306 HydrophobicContact CG-CD2 4.26Å; L238-Y306 HydrophobicContact CG-CE2 4.4Å; L238-Y306 HydrophobicContact CG-CG 4.42Å; L238-I308 HydrophobicContact CD1-CD1 4.18Å; L238-I308 HydrophobicContact CD2-CD1 4.05Å; L238-I308 HydrophobicContact CD2-CG1 4.35Å
239D98.2Very high96.4Very high43 Ų4339.4 Ų39.423%0.2322%0.216CC..Hα-helixtrans-64-40.8174.7-75.3-27.2000112K235 E236 K242 E243 Y306K235-D239 IonicContact NZ-OD1 3.07Å; K235-D239 IonicContact NZ-OD2 2.69Å; K235-D239 PolarHBondContact NZ-OD2 2.85Å; K235-D239 PolarHBondContact O-N 3.46Å; E236-D239 PolarHBondContact O-N 3.34Å; D239-K242 PolarHBondContact O-N 2.89Å; D239-E243 WeakPolarHBondContact O-CB 3.23Å; D239-E243 PolarHBondContact O-N 2.79Å; D239-Y306 VanDerWaalsContact CG-OH 3.24Å; D239-Y306 VanDerWaalsContact OD1-CE1 3.29Å; D239-Y306 WeakPolarHBondContact OD1-CE1 3.47Å; D239-Y306 PolarHBondContact OD1-OH 3.49Å
240L98.3Very high96.5Very high0 Ų040.4 Ų40.40%022%0.22CC..Hα-helixtrans-60.7-44.9173.1-81.1170.4000112I167 L206 C209 I210 Y214 I231 E236 A237 E243 A244I167-L240 HydrophobicContact CD1-CB 4.35Å; I167-L240 HydrophobicContact CD1-CD1 4.39Å; L206-L240 HydrophobicContact CD1-CB 3.89Å; C209-L240 HydrophobicContact CB-CD2 4.08Å; I210-L240 HydrophobicContact CD1-CD1 4.45Å; I210-L240 HydrophobicContact CG1-CD1 3.83Å; I210-L240 HydrophobicContact CG1-CD2 4.04Å; Y214-L240 HydrophobicContact CE2-CD1 3.88Å; Y214-L240 HydrophobicContact CE2-CD2 4.13Å; Y214-L240 HydrophobicContact CE2-CG 4.3Å; I231-L240 HydrophobicContact CD1-CD1 3.87Å; E236-L240 WeakPolarHBondContact O-CG 3.34Å; E236-L240 PolarHBondContact O-N 2.77Å; A237-L240 WeakPolarHBondContact O-CB 3.42Å; A237-L240 PolarHBondContact O-N 3.13Å; L240-E243 PolarHBondContact O-N 2.93Å; L240-A244 WeakPolarHBondContact O-CB 3.47Å; L240-A244 PolarHBondContact O-N 2.74Å
241L98.6Very high96.7Very high0 Ų041.8 Ų41.80%022%0.223CC..Hα-helixtrans-63.3-45177.2-66.9-167.6000111.5V166 I167 F182 L184 L206 A237 L238 E243 A244 I245 I256V166-L241 HydrophobicContact CG2-CD2 3.51Å; I167-L241 HydrophobicContact CD1-CD2 3.76Å; I167-L241 HydrophobicContact CD1-CG 4.05Å; I167-L241 HydrophobicContact CG1-CD2 4.13Å; F182-L241 HydrophobicContact CB-CD1 3.67Å; L184-L241 HydrophobicContact CD2-CD1 4.47Å; L184-L241 HydrophobicContact CD2-CD2 4.19Å; L206-L241 HydrophobicContact CD1-CD2 4.15Å; L206-L241 HydrophobicContact CD2-CD2 3.73Å; A237-L241 WeakPolarHBondContact O-CG 3.33Å; A237-L241 PolarHBondContact O-N 2.82Å; L238-L241 PolarHBondContact O-N 2.88Å; L241-E243 VanDerWaalsContact C-N 3.34Å; L241-E243 PolarHBondContact O-N 3.29Å; L241-A244 PolarHBondContact O-N 3.45Å; L241-I245 WeakPolarHBondContact O-CB 3.44Å; L241-I245 WeakPolarHBondContact O-CD1 3.16Å; L241-I245 WeakPolarHBondContact O-CG1 3.36Å; L241-I245 PolarHBondContact O-N 2.8Å; L241-I256 HydrophobicContact CB-CD1 3.84Å; L241-I256 HydrophobicContact CB-CG1 4.46Å; L241-I256 HydrophobicContact CD1-CD1 4.18Å; L241-I256 HydrophobicContact CD1-CG1 4.23Å; L241-I256 HydrophobicContact CD1-CG2 4.01Å
242K98.2Very high97Very high106 Ų10644.1 Ų44.146%0.46125%0.248SC..Hα-helixtrans-58.1-46.4176.8-175.4177.9179.6175.80111.5L238 D239 A246 Y306L238-K242 WeakPolarHBondContact O-CB 3.05Å; L238-K242 PolarHBondContact O-N 2.78Å; D239-K242 PolarHBondContact O-N 2.89Å; K242-A246 WeakPolarHBondContact O-CB 3.5Å; K242-A246 PolarHBondContact O-N 2.74Å; K242-A246 VanDerWaalsContact O-N 3.07Å; K242-Y306 HydrophobicContact CD-CD1 4.42Å; K242-Y306 HydrophobicContact CD-CE1 4.43Å
243E98.3Very high97.7Very high67 Ų6745.9 Ų45.931%0.31325%0.248SC..Hα-helixtrans-61.2-47.5176-173.3-170.1148.100111.6C209 R213 D239 L240 L241 I245 A246 K247C209-E243 PolarHBondContact SG-OE1 2.88Å; R213-E243 IonicContact CZ-OE2 3.73Å; R213-E243 IonicContact NE-OE2 2.67Å; R213-E243 PolarHBondContact NE-OE2 3.33Å; R213-E243 IonicContact NH2-OE2 2.77Å; R213-E243 PolarHBondContact NH2-OE2 2.93Å; D239-E243 WeakPolarHBondContact O-CB 3.23Å; D239-E243 PolarHBondContact O-N 2.79Å; L240-E243 PolarHBondContact O-N 2.93Å; L241-E243 VanDerWaalsContact C-N 3.34Å; L241-E243 PolarHBondContact O-N 3.29Å; E243-I245 PolarHBondContact O-N 2.72Å; E243-A246 PolarHBondContact O-N 2.89Å; E243-K247 VanDerWaalsContact O-CB 3.29Å; E243-K247 WeakPolarHBondContact O-CB 3.46Å; E243-K247 PolarHBondContact O-N 3.18Å
244A98.7Very high98Very high0 Ų042.8 Ų42.80%023%0.231CC..Hα-helixtrans-64.5-39-178.100000112.5V202 L206 L240 L241 S248V202-A244 HydrophobicContact CG1-CB 3.84Å; L206-A244 HydrophobicContact CB-CB 3.76Å; L206-A244 HydrophobicContact CD1-CB 4.15Å; L240-A244 WeakPolarHBondContact O-CB 3.47Å; L240-A244 PolarHBondContact O-N 2.74Å; L241-A244 PolarHBondContact O-N 3.45Å; A244-S248 WeakPolarHBondContact O-CB 3.35Å; A244-S248 PolarHBondContact O-N 2.66Å; A244-S248 VanDerWaalsContact O-N 3.14Å; A244-S248 PolarHBondContact O-OG 2.94Å
245I98.8Very high98.1Very high7 Ų744.6 Ų44.64%0.03624%0.239CC..Hα-helixtrans-63.5-47.9175.3-69.4164.7000110.4L184 V202 L241 E243 S248 G249 Y250 E251 I254 I256L184-I245 HydrophobicContact CD2-CD1 3.86Å; L184-I245 HydrophobicContact CD2-CG1 3.96Å; V202-I245 HydrophobicContact CG1-CG1 3.98Å; L241-I245 WeakPolarHBondContact O-CB 3.44Å; L241-I245 WeakPolarHBondContact O-CD1 3.16Å; L241-I245 WeakPolarHBondContact O-CG1 3.36Å; L241-I245 PolarHBondContact O-N 2.8Å; E243-I245 PolarHBondContact O-N 2.72Å; I245-S248 PolarHBondContact O-N 3Å; I245-G249 PolarHBondContact O-N 3.46Å; I245-Y250 PolarHBondContact O-N 3.3Å; I245-Y250 VanDerWaalsContact O-N 3.17Å; I245-E251 HydrophobicContact CG2-CG 4.35Å; I245-I254 HydrophobicContact CD1-CB 4.3Å; I245-I254 HydrophobicContact CD1-CG2 3.79Å; I245-I254 HydrophobicContact CG1-CB 4.29Å; I245-I254 HydrophobicContact CG1-CG2 4.01Å; I245-I254 HydrophobicContact CG2-CB 4.25Å; I245-I256 HydrophobicContact CD1-CD1 4.43Å; I245-I256 HydrophobicContact CD1-CG1 4.16Å
246A98.5Very high98.3Very high37 Ų3741.2 Ų41.231%0.30622%0.224SC..Hα-helixtrans-61.2-46.8177.800000112.2K242 E243 S248 G249 E251K242-A246 WeakPolarHBondContact O-CB 3.5Å; K242-A246 PolarHBondContact O-N 2.74Å; K242-A246 VanDerWaalsContact O-N 3.07Å; E243-A246 PolarHBondContact O-N 2.89Å; A246-S248 PolarHBondContact O-N 3.46Å; A246-S248 VanDerWaalsContact O-N 3.15Å; A246-G249 PolarHBondContact O-N 3.46Å; A246-E251 HydrophobicContact CB-CG 3.93Å
247K98.4Very high98.4Very high117 Ų11738.2 Ų38.251%0.50921%0.21SC..Hα-helixtrans-59.4-27.1176.4-173.8173.5179.3178.50113.3N205 E243N205-K247 HydrophobicContact CB-CD 4.28Å; E243-K247 VanDerWaalsContact O-CB 3.29Å; E243-K247 WeakPolarHBondContact O-CB 3.46Å; E243-K247 PolarHBondContact O-N 3.18Å
248S98.5Very high98.4Very high16 Ų1638.2 Ų38.211%0.11221%0.21CC..THydrogen-bonded Turntrans-89.7-3.5178.2-49.30000113.5V202 N205 A244 I245 A246 Y250V202-S248 WeakPolarHBondContact CA-OG 3.32Å; N205-S248 PolarHBondContact ND2-OG 2.85Å; A244-S248 WeakPolarHBondContact O-CB 3.35Å; A244-S248 PolarHBondContact O-N 2.66Å; A244-S248 VanDerWaalsContact O-N 3.14Å; A244-S248 PolarHBondContact O-OG 2.94Å; I245-S248 PolarHBondContact O-N 3Å; A246-S248 PolarHBondContact O-N 3.46Å; A246-S248 VanDerWaalsContact O-N 3.15Å; S248-Y250 WeakPolarHBondContact O-CE2 3.23Å
249G98.4Very high98.4Very high55 Ų5538.3 Ų38.357%0.56721%0.21SC*.THydrogen-bonded Turntrans72.524.3-17900000114.4I245 A246I245-G249 PolarHBondContact O-N 3.46Å; A246-G249 PolarHBondContact O-N 3.46Å
250Y98.6Very high98.4Very high20 Ų2036.2 Ų36.28%0.07820%0.199CC..  trans-112.520.4-176.6-59.1-43.4000114.7R197 M198 E201 V202 I245 S248 G252 K253 I254R197-Y250 PolarHBondContact NH1-OH 3.01Å; R197-Y250 PolarHBondContact NH2-OH 2.9Å; M198-Y250 HydrophobicContact CB-CD2 4.08Å; M198-Y250 HydrophobicContact CB-CE2 3.97Å; M198-Y250 HydrophobicContact CB-CG 4.5Å; M198-Y250 HydrophobicContact CE-CD1 3.88Å; M198-Y250 HydrophobicContact CE-CG 3.92Å; M198-Y250 HydrophobicContact CG-CD1 4.01Å; M198-Y250 HydrophobicContact CG-CD2 4.16Å; M198-Y250 HydrophobicContact CG-CE1 3.74Å; M198-Y250 HydrophobicContact CG-CE2 3.91Å; M198-Y250 HydrophobicContact CG-CG 4.24Å; M198-Y250 HydrophobicContact SD-CD1 4.39Å; M198-Y250 HydrophobicContact SD-CE1 4.48Å; E201-Y250 HydrophobicContact CB-CE2 4.23Å; E201-Y250 WeakPolarHBondContact OE2-CE2 3.29Å; E201-Y250 VanDerWaalsContact OE2-CZ 3.31Å; E201-Y250 PolarHBondContact OE2-OH 3.45Å; V202-Y250 HydrophobicContact CG2-CD2 3.73Å; V202-Y250 HydrophobicContact CG2-CE2 4.43Å; I245-Y250 PolarHBondContact O-N 3.3Å; I245-Y250 VanDerWaalsContact O-N 3.17Å; S248-Y250 WeakPolarHBondContact O-CE2 3.23Å; Y250-G252 PolarHBondContact O-N 2.94Å; Y250-K253 PolarHBondContact O-N 3.5Å; Y250-I254 HydrophobicContact CD2-CD1 3.81Å; Y250-I254 HydrophobicContact CG-CD1 4.01Å; Y250-I254 PolarHBondContact O-N 3.45Å
251E97.6Very high98.4Very high130 Ų13036.3 Ų36.361%0.60720%0.2SC*.THydrogen-bonded Turntrans-54.1138.3171-71.9175.8106.200111I245 A246 K253I245-E251 HydrophobicContact CG2-CG 4.35Å; A246-E251 HydrophobicContact CB-CG 3.93Å; E251-K253 PolarHBondContact O-N 2.99Å
252G96.4Very high98.4Very high50 Ų5036.3 Ų36.352%0.51520%0.2SC..THydrogen-bonded Turntrans77.3-31.3-174.500000114.5Y250 K255Y250-G252 PolarHBondContact O-N 2.94Å; G252-K255 PolarHBondContact O-NZ 3.26Å
253K98.5Very high98.3Very high106 Ų10632.4 Ų32.446%0.46119%0.186SC..THydrogen-bonded Turntrans-90-28.5-177.2-57.2-176.1179178.60114.4P186 V187 G188 M198 Y250 E251P186-K253 CarbonylContact C-O 3.54Å; V187-K253 PolarHBondContact N-O 2.96Å; G188-K253 PolarHBondContact N-O 3.48Å; M198-K253 HydrophobicContact CE-CB 3.61Å; M198-K253 HydrophobicContact CE-CD 4.33Å; Y250-K253 PolarHBondContact O-N 3.5Å; E251-K253 PolarHBondContact O-N 2.99Å
254I98.8Very high98.2Very high3 Ų332.1 Ų32.12%0.01519%0.185CC..  trans-107.3128.4171.7-63.7175.2000108.9L184 M185 P186 M198 V202 I245 Y250L184-I254 HydrophobicContact CB-CG2 3.94Å; L184-I254 HydrophobicContact CD2-CG2 4Å; M185-I254 WeakPolarHBondContact O-CA 3.16Å; P186-I254 HydrophobicContact CB-CG1 4.08Å; M198-I254 HydrophobicContact CB-CD1 4.21Å; M198-I254 HydrophobicContact CE-CD1 4.12Å; M198-I254 HydrophobicContact CE-CG1 3.63Å; V202-I254 HydrophobicContact CB-CD1 4.46Å; V202-I254 HydrophobicContact CG2-CD1 3.38Å; I245-I254 HydrophobicContact CD1-CB 4.3Å; I245-I254 HydrophobicContact CD1-CG2 3.79Å; I245-I254 HydrophobicContact CG1-CB 4.29Å; I245-I254 HydrophobicContact CG1-CG2 4.01Å; I245-I254 HydrophobicContact CG2-CB 4.25Å; Y250-I254 HydrophobicContact CD2-CD1 3.81Å; Y250-I254 HydrophobicContact CG-CD1 4.01Å; Y250-I254 PolarHBondContact O-N 3.45Å
255K98.6Very high98.1Very high46 Ų4632.1 Ų32.120%0.219%0.185CC..EExtended strand (participates in β ladder)trans-103170.3170.6-52.2-60-176-163.80109.8M185 V187 G252 P307 V309M185-K255 PolarHBondContact N-O 3.15Å; M185-K255 PolarHBondContact O-N 2.71Å; V187-K255 HydrophobicContact CG1-CG 4.41Å; V187-K255 HydrophobicContact CG2-CD 4.36Å; V187-K255 HydrophobicContact CG2-CG 3.5Å; G252-K255 PolarHBondContact O-NZ 3.26Å; K255-P307 WeakPolarHBondContact CB-O 3.4Å; K255-P307 HydrophobicContact CD-CB 4.19Å; K255-V309 HydrophobicContact CB-CB 4.32Å; K255-V309 HydrophobicContact CB-CG1 3.79Å; K255-V309 HydrophobicContact CB-CG2 3.57Å; K255-V309 HydrophobicContact CD-CG1 4.15Å; K255-V309 HydrophobicContact CG-CG1 3.77Å; K255-V309 HydrophobicContact CG-CG2 4.19Å
256I98.8Very high98.1Very high0 Ų033.9 Ų33.90%019%0.192CC..EExtended strand (participates in β ladder)trans-106.9143.7177.7-63.1174.1000109.4M183 L238 L241 I245 M258 P307 I308 V309M183-I256 WeakPolarHBondContact O-CA 3.46Å; L238-I256 HydrophobicContact CD2-CD1 4.32Å; L238-I256 HydrophobicContact CD2-CG2 3.83Å; L241-I256 HydrophobicContact CB-CD1 3.84Å; L241-I256 HydrophobicContact CB-CG1 4.46Å; L241-I256 HydrophobicContact CD1-CD1 4.18Å; L241-I256 HydrophobicContact CD1-CG1 4.23Å; L241-I256 HydrophobicContact CD1-CG2 4.01Å; I245-I256 HydrophobicContact CD1-CD1 4.43Å; I245-I256 HydrophobicContact CD1-CG1 4.16Å; I256-M258 HydrophobicContact CG2-CG 4.46Å; I256-P307 HydrophobicContact CD1-CG 4.43Å; I256-P307 PolarHBondContact N-O 3.11Å; I256-I308 HydrophobicContact CB-CG1 4.07Å; I256-I308 HydrophobicContact CG2-CG1 3.98Å; I256-I308 CarbonylContact O-C 3.54Å; I256-I308 VanDerWaalsContact O-CA 3.26Å; I256-I308 WeakPolarHBondContact O-CA 3.25Å; I256-V309 PolarHBondContact O-N 2.78Å
257A98.8Very high98Very high0 Ų035.2 Ų35.20%019%0.191CC..EExtended strand (participates in β ladder)trans-125.6160.6163.200000110M183 M185 S310M183-A257 HydrophobicContact CB-CB 3.96Å; M183-A257 HydrophobicContact CE-CB 3.98Å; M183-A257 PolarHBondContact N-O 3.28Å; M183-A257 PolarHBondContact O-N 2.76Å; M185-A257 HydrophobicContact CG-CB 4.02Å; M185-A257 HydrophobicContact SD-CB 3.58Å; M185-A257 VanDerWaalsContact SD-CB 3.58Å; A257-S310 CarbonylContact C-O 3.13Å; A257-S310 VanDerWaalsContact CA-O 3.23Å; A257-S310 WeakPolarHBondContact CA-O 3.25Å
258M98.6Very high97.8Very high0 Ų036.4 Ų36.40%020%0.198CC..EExtended strand (participates in β ladder)trans-134.6141.4179.8-62.1172.161.200110.2M179 E181 F182 L238 I256 Y302 I308 S310 I311 E312M179-M258 HydrophobicContact SD-CE 3.31Å; M179-M258 WeakPolarHBondContact SD-CE 3.25Å; E181-M258 WeakPolarHBondContact O-CA 3.3Å; F182-M258 HydrophobicContact CD1-CE 4.3Å; F182-M258 HydrophobicContact CD1-CG 4.2Å; F182-M258 HydrophobicContact CE1-CE 3.71Å; F182-M258 HydrophobicContact CE1-SD 4.48Å; F182-M258 HydrophobicContact CZ-CE 4.28Å; L238-M258 HydrophobicContact CD1-SD 4.31Å; L238-M258 HydrophobicContact CD2-CG 4.49Å; L238-M258 HydrophobicContact CD2-SD 4.02Å; I256-M258 HydrophobicContact CG2-CG 4.46Å; M258-Y302 HydrophobicContact CE-CD2 4.26Å; M258-Y302 HydrophobicContact CE-CE2 4.47Å; M258-I308 HydrophobicContact SD-CD1 3.63Å; M258-I308 HydrophobicContact SD-CG1 4.34Å; M258-S310 PolarHBondContact N-O 2.48Å; M258-I311 HydrophobicContact CB-CG1 4.43Å; M258-I311 CarbonylContact O-C 3.56Å; M258-I311 WeakPolarHBondContact O-CA 3.48Å; M258-E312 PolarHBondContact O-N 3.29Å
259D98.6Very high97.6Very high1 Ų138.7 Ų38.71%0.00521%0.207CC..EExtended strand (participates in β ladder)trans-109.8116.4159.1175.710.6000107.8Q180 E181 M183 A261 E312 K413Q180-D259 PolarHBondContact N-O 2.8Å; Q180-D259 PolarHBondContact NE2-OD2 2.83Å; Q180-D259 VanDerWaalsContact NE2-OD2 3.16Å; E181-D259 HydrophobicContact CB-CB 3.89Å; E181-D259 HydrophobicContact CG-CB 3.98Å; E181-D259 PolarHBondContact N-O 2.75Å; E181-D259 PolarHBondContact O-N 3.07Å; M183-D259 HydrophobicContact CE-CB 4.12Å; D259-A261 PolarHBondContact OD1-N 2.67Å; D259-E312 HydrophobicContact CB-CB 4.12Å; D259-E312 HydrophobicContact CB-CG 4.23Å; D259-K413 IonicContact OD2-NZ 3.43Å; D259-K413 PolarHBondContact OD2-NZ 3.25Å
260V98.5Very high97.3Very high0 Ų042.6 Ų42.60%022%0.215CC..  trans-84-38.1-178.2175.20000110.3M179 Q180 A262 F265 Y299 I311 E312 D313M179-V260 HydrophobicContact CG-CG1 4.31Å; M179-V260 HydrophobicContact SD-CG2 4.4Å; Q180-V260 PolarHBondContact N-O 3.2Å; V260-A262 HydrophobicContact CG1-CB 3.82Å; V260-F265 HydrophobicContact CG1-CE1 3.93Å; V260-F265 HydrophobicContact CG1-CZ 3.48Å; V260-F265 VanDerWaalsContact CG1-CZ 3.48Å; V260-F265 WeakPolarHBondContact O-CE1 3.31Å; V260-Y299 HydrophobicContact CG1-CE1 4.45Å; V260-Y299 VanDerWaalsContact CG1-OH 3.24Å; V260-Y299 WeakPolarHBondContact CG1-OH 3.47Å; V260-Y299 HydrophobicContact CG2-CE1 3.82Å; V260-I311 HydrophobicContact CG2-CG2 3.92Å; V260-E312 PolarHBondContact N-O 2.9Å; V260-D313 WeakPolarHBondContact CB-O 3.3Å
261A97.6Very high97.1Very high2 Ų244.7 Ų44.72%0.01724%0.243CC..  trans49.150.5-168.800000113.1Q180 D259 S263 E264Q180-A261 HydrophobicContact CB-CB 3.78Å; Q180-A261 HydrophobicContact CG-CB 4.36Å; D259-A261 PolarHBondContact OD1-N 2.67Å; A261-S263 PolarHBondContact O-N 3.32Å; A261-S263 VanDerWaalsContact O-N 3.08Å; A261-E264 HydrophobicContact CB-CG 4.07Å; A261-E264 WeakPolarHBondContact O-CB 3.37Å; A261-E264 PolarHBondContact O-N 2.83Å
262A98.2Very high97Very high0 Ų044.9 Ų44.90%024%0.242CC..G310 helixtrans-62.4-22.2-16900000115V260 E264 F265 F266 Y275 D313V260-A262 HydrophobicContact CG1-CB 3.82Å; A262-E264 PolarHBondContact O-N 2.77Å; A262-F265 HydrophobicContact CB-CE1 4.44Å; A262-F265 HydrophobicContact CB-CE2 3.99Å; A262-F265 HydrophobicContact CB-CZ 3.82Å; A262-F265 PolarHBondContact O-N 2.93Å; A262-F266 PolarHBondContact O-N 2.77Å; A262-F266 VanDerWaalsContact O-N 3.13Å; A262-Y275 HydrophobicContact CB-CD1 4.16Å; A262-Y275 HydrophobicContact CB-CE1 3.84Å; A262-D313 VanDerWaalsContact CB-O 3.26Å; A262-D313 WeakPolarHBondContact CB-O 3.34Å; A262-D313 PolarHBondContact N-O 3.05Å
263S97.6Very high96.9Very high23 Ų2347.9 Ų47.916%0.16124%0.241CC..G310 helixtrans-57-33.1172.2-56.80000112.6A261 F265 F266 Q317A261-S263 PolarHBondContact O-N 3.32Å; A261-S263 VanDerWaalsContact O-N 3.08Å; S263-F265 VanDerWaalsContact C-N 3.25Å; S263-F265 PolarHBondContact O-N 2.9Å; S263-F266 PolarHBondContact O-N 2.91Å; S263-Q317 PolarHBondContact OG-N 2.98Å; S263-Q317 VanDerWaalsContact OG-N 3.14Å
264E96.1Very high96.9Very high62 Ų6243.9 Ų43.929%0.2922%0.224SC..G310 helixtrans-69-23.8-176.6-62.8-66.1120.800113.3S54 S171 A261 A262S54-E264 WeakPolarHBondContact CB-OE1 3.47Å; S54-E264 PolarHBondContact OG-OE1 3.13Å; S171-E264 PolarHBondContact OG-OE2 3Å; A261-E264 HydrophobicContact CB-CG 4.07Å; A261-E264 WeakPolarHBondContact O-CB 3.37Å; A261-E264 PolarHBondContact O-N 2.83Å; A262-E264 PolarHBondContact O-N 2.77Å
265F96.7Very high96.9Very high0 Ų043.8 Ų43.80%022%0.223CC..G310 helixtrans-120.914.6-179.957.6-105000113.4A178 V260 A262 S263 Y275 D276 L277 F279 M295A178-F265 HydrophobicContact CB-CD1 4.29Å; A178-F265 HydrophobicContact CB-CE1 4.44Å; V260-F265 HydrophobicContact CG1-CE1 3.93Å; V260-F265 HydrophobicContact CG1-CZ 3.48Å; V260-F265 VanDerWaalsContact CG1-CZ 3.48Å; V260-F265 WeakPolarHBondContact O-CE1 3.31Å; A262-F265 HydrophobicContact CB-CE1 4.44Å; A262-F265 HydrophobicContact CB-CE2 3.99Å; A262-F265 HydrophobicContact CB-CZ 3.82Å; A262-F265 PolarHBondContact O-N 2.93Å; S263-F265 VanDerWaalsContact C-N 3.25Å; S263-F265 PolarHBondContact O-N 2.9Å; F265-Y275 AromaticContact CD2-CD1 3.9Å; F265-Y275 HydrophobicContact CD2-CD1 3.9Å; F265-Y275 HydrophobicContact CD2-CG 4.42Å; F265-Y275 AromaticContact CE2-CD1 3.73Å; F265-Y275 HydrophobicContact CE2-CD1 3.73Å; F265-Y275 HydrophobicContact CE2-CG 4.26Å; F265-Y275 WeakPolarHBondContact O-CA 3.38Å; F265-D276 WeakPolarHBondContact CB-O 3.28Å; F265-D276 PolarHBondContact O-N 2.77Å; F265-L277 HydrophobicContact CD2-CD2 4.05Å; F265-L277 HydrophobicContact CE1-CD2 4.5Å; F265-L277 HydrophobicContact CE2-CD2 3.61Å; F265-L277 HydrophobicContact CZ-CD2 3.84Å; F265-F279 HydrophobicContact CB-CB 3.81Å; F265-F279 HydrophobicContact CB-CD1 3.53Å; F265-F279 HydrophobicContact CB-CE1 4.16Å; F265-F279 HydrophobicContact CB-CG 3.71Å; F265-F279 HydrophobicContact CD1-CD1 4.44Å; F265-F279 HydrophobicContact CD1-CE1 4.38Å; F265-F279 HydrophobicContact CG-CD1 4.4Å; F265-M295 HydrophobicContact CE2-CE 4.04Å; F265-M295 HydrophobicContact CZ-CE 4.33Å
266F97.6Very high96.8Very high43 Ų4341.7 Ų41.719%0.18922%0.215CC..EExtended strand (participates in β ladder)trans-76.6135.7170.8178.6-95.4000111.1A262 S263 K273 L274 Y275 E316A262-F266 PolarHBondContact O-N 2.77Å; A262-F266 VanDerWaalsContact O-N 3.13Å; S263-F266 PolarHBondContact O-N 2.91Å; F266-K273 HydrophobicContact CE2-CB 3.68Å; F266-K273 HydrophobicContact CE2-CD 4.32Å; F266-K273 HydrophobicContact CE2-CG 4.19Å; F266-K273 HydrophobicContact CZ-CB 3.68Å; F266-K273 HydrophobicContact CZ-CD 3.84Å; F266-K273 HydrophobicContact CZ-CG 3.68Å; F266-L274 WeakPolarHBondContact CA-O 3.21Å; F266-Y275 HydrophobicContact CB-CD1 4.3Å; F266-Y275 HydrophobicContact CB-CE1 4.19Å; F266-Y275 HydrophobicContact CD2-CD1 4.16Å; F266-Y275 AromaticContact CD2-CE1 3.69Å; F266-Y275 HydrophobicContact CD2-CE1 3.69Å; F266-Y275 HydrophobicContact CD2-CE2 4.3Å; F266-Y275 AromaticContact CD2-CZ 3.77Å; F266-Y275 HydrophobicContact CG-CE1 4.44Å; F266-E316 HydrophobicContact CB-CB 3.92Å; F266-E316 HydrophobicContact CB-CG 3.84Å; F266-E316 HydrophobicContact CD1-CB 4.33Å; F266-E316 HydrophobicContact CD1-CG 3.74Å; F266-E316 HydrophobicContact CD2-CB 3.61Å; F266-E316 HydrophobicContact CD2-CG 3.98Å; F266-E316 HydrophobicContact CE1-CG 4.24Å; F266-E316 HydrophobicContact CE2-CB 4.11Å; F266-E316 HydrophobicContact CE2-CG 4.41Å; F266-E316 HydrophobicContact CG-CB 3.7Å; F266-E316 HydrophobicContact CG-CG 3.58Å
267K96.5Very high96.7Very high65 Ų6543.6 Ų43.628%0.28323%0.225SC..EExtended strand (participates in β ladder)trans-140.3141.1178.2-65.2-177.3179.2173.80110.6L274 D276 W289K267-L274 PolarHBondContact N-O 3.09Å; K267-L274 PolarHBondContact O-N 3.05Å; K267-L274 VanDerWaalsContact O-O 3.09Å; K267-D276 HydrophobicContact CD-CB 4.04Å; K267-D276 WeakPolarHBondContact CE-OD2 3.36Å; K267-D276 IonicContact NZ-OD2 3.55Å; K267-D276 PolarHBondContact NZ-OD2 3.45Å; K267-W289 HydrophobicContact CB-CE3 4.23Å; K267-W289 HydrophobicContact CB-CH2 4.25Å; K267-W289 HydrophobicContact CB-CZ3 3.7Å; K267-W289 HydrophobicContact CD-CE3 4.42Å; K267-W289 HydrophobicContact CD-CH2 3.38Å; K267-W289 HydrophobicContact CD-CZ2 3.76Å; K267-W289 HydrophobicContact CD-CZ3 3.72Å; K267-W289 HydrophobicContact CG-CH2 4.44Å; K267-W289 HydrophobicContact CG-CZ3 4.34Å
268E94.7Very high96.6Very high142 Ų14246.3 Ų46.366%0.66424%0.239SC*.EExtended strand (participates in β ladder)trans-92.6123.9163.6-168.2175.6147.900109.4K272E268-K272 WeakPolarHBondContact CA-O 3.2Å
269H94.2Very high96.4Very high65 Ų6548.3 Ų48.330%0.30125%0.248SC..EExtended strand (participates in β ladder)trans-142.2127.1179.6179.675.8000110.3G271 K272 L274 P286 W289H269-G271 PolarHBondContact O-N 2.94Å; H269-K272 PolarHBondContact N-O 2.91Å; H269-K272 WeakPolarHBondContact O-CB 3.1Å; H269-K272 PolarHBondContact O-N 3.28Å; H269-L274 HydrophobicContact CB-CD1 4.48Å; H269-P286 WeakPolarHBondContact NE2-CB 3.05Å; H269-W289 HydrophobicContact CB-CE3 4.16Å; H269-W289 HydrophobicContact CB-CH2 4.49Å; H269-W289 HydrophobicContact CB-CZ3 3.56Å; H269-W289 AromaticContact CG-CZ3 3.94Å
270D93.1Very high96.2Very high136 Ų13651.5 Ų51.573%0.72726%0.262SS*.THydrogen-bonded Turntrans49.640.7-173.8-62.2-18.6000113.4K272D270-K272 PolarHBondContact O-N 2.9Å
271G93.1Very high96Very high65 Ų6554.1 Ų54.167%0.6728%0.276SS*.THydrogen-bonded Turntrans70.39.9-17800000114.7H269H269-G271 PolarHBondContact O-N 2.94Å
272K95.1Very high95.7Very high134 Ų13460.2 Ų60.258%0.58332%0.315SS*.EExtended strand (participates in β ladder)trans-105.7136.5176.9-60.9175-175.4169.20110.6E268 H269 D270 L274E268-K272 WeakPolarHBondContact CA-O 3.2Å; H269-K272 PolarHBondContact N-O 2.91Å; H269-K272 WeakPolarHBondContact O-CB 3.1Å; H269-K272 PolarHBondContact O-N 3.28Å; D270-K272 PolarHBondContact O-N 2.9Å; K272-L274 HydrophobicContact CB-CD1 4.21Å; K272-L274 HydrophobicContact CB-CD2 4.33Å; K272-L274 HydrophobicContact CB-CG 4.01Å
273K96.2Very high95.6Very high113 Ų11369 Ų6949%0.49135%0.353SS..EExtended strand (participates in β ladder)trans-81.4111.5171-66.6-168.2172-167.40109.6F266F266-K273 HydrophobicContact CE2-CB 3.68Å; F266-K273 HydrophobicContact CE2-CD 4.32Å; F266-K273 HydrophobicContact CE2-CG 4.19Å; F266-K273 HydrophobicContact CZ-CB 3.68Å; F266-K273 HydrophobicContact CZ-CD 3.84Å; F266-K273 HydrophobicContact CZ-CG 3.68Å
274L98.1Very high95.5Very high21 Ų2168.6 Ų68.611%0.1135%0.351CS..EExtended strand (participates in β ladder)trans-133.3161.5-172.5-61.3175.6000111.4F266 K267 H269 K272 W289 K290 N291F266-L274 WeakPolarHBondContact CA-O 3.21Å; K267-L274 PolarHBondContact N-O 3.09Å; K267-L274 PolarHBondContact O-N 3.05Å; K267-L274 VanDerWaalsContact O-O 3.09Å; H269-L274 HydrophobicContact CB-CD1 4.48Å; K272-L274 HydrophobicContact CB-CD1 4.21Å; K272-L274 HydrophobicContact CB-CD2 4.33Å; K272-L274 HydrophobicContact CB-CG 4.01Å; L274-W289 HydrophobicContact CB-CB 4.01Å; L274-W289 HydrophobicContact CB-CE3 4.08Å; L274-W289 HydrophobicContact CD1-CB 4.24Å; L274-W289 HydrophobicContact CD1-CE3 4.09Å; L274-K290 CarbonylContact C-O 3.58Å; L274-K290 WeakPolarHBondContact CA-O 3.34Å; L274-N291 HydrophobicContact CD2-CB 3.93Å
275Y98.2Very high95.5Very high1 Ų170.4 Ų70.40%0.00436%0.362CS..EExtended strand (participates in β ladder)trans-121.1119.5-178.5-65.3-85.5000109.7A262 F265 F266 W289 K290 M295 F315 E316 D319A262-Y275 HydrophobicContact CB-CD1 4.16Å; A262-Y275 HydrophobicContact CB-CE1 3.84Å; F265-Y275 AromaticContact CD2-CD1 3.9Å; F265-Y275 HydrophobicContact CD2-CD1 3.9Å; F265-Y275 HydrophobicContact CD2-CG 4.42Å; F265-Y275 AromaticContact CE2-CD1 3.73Å; F265-Y275 HydrophobicContact CE2-CD1 3.73Å; F265-Y275 HydrophobicContact CE2-CG 4.26Å; F265-Y275 WeakPolarHBondContact O-CA 3.38Å; F266-Y275 HydrophobicContact CB-CD1 4.3Å; F266-Y275 HydrophobicContact CB-CE1 4.19Å; F266-Y275 HydrophobicContact CD2-CD1 4.16Å; F266-Y275 AromaticContact CD2-CE1 3.69Å; F266-Y275 HydrophobicContact CD2-CE1 3.69Å; F266-Y275 HydrophobicContact CD2-CE2 4.3Å; F266-Y275 AromaticContact CD2-CZ 3.77Å; F266-Y275 HydrophobicContact CG-CE1 4.44Å; Y275-W289 WeakPolarHBondContact O-CA 3.32Å; Y275-K290 WeakPolarHBondContact CD2-O 3.49Å; Y275-K290 PolarHBondContact N-O 2.86Å; Y275-K290 PolarHBondContact O-N 2.62Å; Y275-M295 HydrophobicContact CD2-CG 3.49Å; Y275-M295 VanDerWaalsContact CD2-CG 3.49Å; Y275-M295 HydrophobicContact CE2-CG 4.2Å; Y275-M295 HydrophobicContact CG-CG 3.74Å; Y275-M295 HydrophobicContact CG-SD 4.3Å; Y275-F315 HydrophobicContact CE2-CD1 4.29Å; Y275-F315 WeakPolarHBondContact OH-CB 3.27Å; Y275-E316 HydrophobicContact CE1-CB 4.16Å; Y275-E316 PolarHBondContact OH-N 3.43Å; Y275-D319 PolarHBondContact OH-OD2 3.33Å
276D97.4Very high95.4Very high3 Ų372.4 Ų72.42%0.01638%0.376CS..  trans-99.291.8-176.4-179.79.4000111.5F265 K267 D278 F279 S284 W289F265-D276 WeakPolarHBondContact CB-O 3.28Å; F265-D276 PolarHBondContact O-N 2.77Å; K267-D276 HydrophobicContact CD-CB 4.04Å; K267-D276 WeakPolarHBondContact CE-OD2 3.36Å; K267-D276 IonicContact NZ-OD2 3.55Å; K267-D276 PolarHBondContact NZ-OD2 3.45Å; D276-D278 PolarHBondContact O-N 2.8Å; D276-D278 VanDerWaalsContact OD1-C 3.32Å; D276-D278 WeakPolarHBondContact OD1-CA 3.41Å; D276-D278 PolarHBondContact OD1-N 3.42Å; D276-F279 HydrophobicContact CB-CB 4.23Å; D276-F279 WeakPolarHBondContact O-CB 3.25Å; D276-F279 PolarHBondContact O-N 2.89Å; D276-F279 PolarHBondContact OD1-N 2.98Å; D276-F279 VanDerWaalsContact OD2-CA 3.29Å; D276-F279 WeakPolarHBondContact OD2-CA 3.39Å; D276-S284 WeakPolarHBondContact OD2-CB 3.49Å; D276-S284 PolarHBondContact OD2-OG 3.2Å; D276-W289 HydrophobicContact CB-CD2 3.97Å; D276-W289 HydrophobicContact CB-CG 4.01Å; D276-W289 HydrophobicContact CB-CZ2 4.38Å; D276-W289 PolarHBondContact OD1-NE1 3.16Å; D276-W289 PolarHBondContact OD2-NE1 3.1Å
277L96.5Very high95.3Very high40 Ų4075.2 Ų75.221%0.20940%0.4CS..THydrogen-bonded Turntrans-681.9178.1-58.8-177000114.1A178 F265 K290 M295 L298A178-L277 HydrophobicContact CB-CB 4.26Å; A178-L277 HydrophobicContact CB-CD2 4.11Å; A178-L277 WeakPolarHBondContact CB-O 3.46Å; F265-L277 HydrophobicContact CD2-CD2 4.05Å; F265-L277 HydrophobicContact CE1-CD2 4.5Å; F265-L277 HydrophobicContact CE2-CD2 3.61Å; F265-L277 HydrophobicContact CZ-CD2 3.84Å; L277-K290 HydrophobicContact CD1-CD 3.88Å; L277-M295 HydrophobicContact CD1-SD 4.41Å; L277-M295 HydrophobicContact CD2-CE 4.09Å; L277-M295 HydrophobicContact CD2-SD 4.27Å; L277-M295 HydrophobicContact CG-SD 4.48Å; L277-L298 HydrophobicContact CD1-CD2 3.78Å
278D95.5Very high95.2Very high56 Ų5674.6 Ų74.630%0.29941%0.413SS..THydrogen-bonded Turntrans-119.428.2170.9-165.632.6000111D276 K280 N281D276-D278 PolarHBondContact O-N 2.8Å; D276-D278 VanDerWaalsContact OD1-C 3.32Å; D276-D278 WeakPolarHBondContact OD1-CA 3.41Å; D276-D278 PolarHBondContact OD1-N 3.42Å; D278-K280 PolarHBondContact O-N 3.33Å; D278-N281 VanDerWaalsContact CG-CB 3.41Å; D278-N281 VanDerWaalsContact O-CB 3.26Å; D278-N281 WeakPolarHBondContact O-CB 3.31Å; D278-N281 PolarHBondContact O-N 3Å; D278-N281 WeakPolarHBondContact OD1-CB 3.31Å; D278-N281 WeakPolarHBondContact OD2-CB 3.41Å; D278-N281 PolarHBondContact OD2-ND2 3.45Å
279F95.2Very high95.4Very high43 Ų4369.2 Ų69.219%0.18939%0.386CS..THydrogen-bonded Turntrans-56.5-23.2-171.778.7-79.6000116A178 F265 D276 N281A178-F279 HydrophobicContact CB-CD1 4.22Å; A178-F279 HydrophobicContact CB-CE1 4.2Å; F265-F279 HydrophobicContact CB-CB 3.81Å; F265-F279 HydrophobicContact CB-CD1 3.53Å; F265-F279 HydrophobicContact CB-CE1 4.16Å; F265-F279 HydrophobicContact CB-CG 3.71Å; F265-F279 HydrophobicContact CD1-CD1 4.44Å; F265-F279 HydrophobicContact CD1-CE1 4.38Å; F265-F279 HydrophobicContact CG-CD1 4.4Å; D276-F279 HydrophobicContact CB-CB 4.23Å; D276-F279 WeakPolarHBondContact O-CB 3.25Å; D276-F279 PolarHBondContact O-N 2.89Å; D276-F279 PolarHBondContact OD1-N 2.98Å; D276-F279 VanDerWaalsContact OD2-CA 3.29Å; D276-F279 WeakPolarHBondContact OD2-CA 3.39Å; F279-N281 VanDerWaalsContact C-N 3.27Å
280K93.7Very high95.6Very high67 Ų6769 Ų6929%0.29139%0.385SS..THydrogen-bonded Turntrans-77.1-14176.3-65.2175.3178172.10112.9G170 A173 N175 L177 D278 P282G170-K280 WeakPolarHBondContact O-CE 3.46Å; G170-K280 PolarHBondContact O-NZ 2.8Å; A173-K280 PolarHBondContact O-NZ 3Å; N175-K280 WeakPolarHBondContact O-CD 3.22Å; N175-K280 WeakPolarHBondContact O-CE 3.23Å; N175-K280 PolarHBondContact O-NZ 3.44Å; L177-K280 PolarHBondContact O-NZ 2.88Å; L177-K280 VanDerWaalsContact O-NZ 3.16Å; D278-K280 PolarHBondContact O-N 3.33Å; K280-P282 WeakPolarHBondContact O-CD 3.3Å
281N94.4Very high95.8Very high55 Ų5565.5 Ų65.529%0.29437%0.366SS..SBendtrans-86.9114.7171.8178.29.1000109.4D278 F279 K283 S284D278-N281 VanDerWaalsContact CG-CB 3.41Å; D278-N281 VanDerWaalsContact O-CB 3.26Å; D278-N281 WeakPolarHBondContact O-CB 3.31Å; D278-N281 PolarHBondContact O-N 3Å; D278-N281 WeakPolarHBondContact OD1-CB 3.31Å; D278-N281 WeakPolarHBondContact OD2-CB 3.41Å; D278-N281 PolarHBondContact OD2-ND2 3.45Å; F279-N281 VanDerWaalsContact C-N 3.27Å; N281-K283 PolarHBondContact O-N 3.24Å; N281-K283 WeakPolarHBondContact OD1-CB 3.31Å; N281-K283 PolarHBondContact OD1-N 2.94Å; N281-S284 WeakPolarHBondContact O-CB 3.41Å; N281-S284 PolarHBondContact O-N 3.1Å; N281-S284 PolarHBondContact O-OG 3.04Å
282P92.6Very high96Very high131 Ų13162.7 Ų62.785%0.85134%0.336SS*.THydrogen-bonded Turntrans-61.4-12.5176.4-22.634.5000114.1K280K280-P282 WeakPolarHBondContact O-CD 3.3Å
283K95.1Very high96.2Very high183 Ų18360.1 Ų60.180%0.79633%0.329SS*.THydrogen-bonded Turntrans-11021.7176.9-56.2-178.5-180-179.90112.6N281 D285N281-K283 PolarHBondContact O-N 3.24Å; N281-K283 WeakPolarHBondContact OD1-CB 3.31Å; N281-K283 PolarHBondContact OD1-N 2.94Å; K283-D285 PolarHBondContact O-N 2.9Å
284S95.5Very high96.3Very high16 Ų1659 Ų5911%0.11233%0.326CS..  trans-49.2127.6173.859.30000110.4D276 N281 P286D276-S284 WeakPolarHBondContact OD2-CB 3.49Å; D276-S284 PolarHBondContact OD2-OG 3.2Å; N281-S284 WeakPolarHBondContact O-CB 3.41Å; N281-S284 PolarHBondContact O-N 3.1Å; N281-S284 PolarHBondContact O-OG 3.04Å; S284-P286 WeakPolarHBondContact O-CD 3.42Å
285D95.4Very high96.3Very high99 Ų9958 Ų5853%0.52932%0.32SS..  trans-82.8117.8-179.4179.82.1000110.9K283 S287 G288 W289K283-D285 PolarHBondContact O-N 2.9Å; D285-S287 PolarHBondContact O-N 3.21Å; D285-S287 VanDerWaalsContact O-N 3.08Å; D285-S287 WeakPolarHBondContact OD1-CB 3.48Å; D285-S287 PolarHBondContact OD1-N 3.12Å; D285-S287 PolarHBondContact OD1-OG 3.44Å; D285-S287 PolarHBondContact OD2-OG 2.87Å; D285-G288 PolarHBondContact O-N 3.47Å; D285-W289 VanDerWaalsContact O-CD1 3.26Å; D285-W289 PolarHBondContact O-NE1 3.45Å
286P95.4Very high96.3Very high43 Ų4358.5 Ų58.528%0.27932%0.323SS..G310 helixtrans-56.9-23.1177.2-23.534.2000114.9H269 S284 G288 W289H269-P286 WeakPolarHBondContact NE2-CB 3.05Å; S284-P286 WeakPolarHBondContact O-CD 3.42Å; P286-G288 PolarHBondContact O-N 3.08Å; P286-W289 HydrophobicContact CB-CD2 4.1Å; P286-W289 HydrophobicContact CB-CE3 4.18Å; P286-W289 HydrophobicContact CB-CH2 4.33Å; P286-W289 HydrophobicContact CB-CZ2 4.26Å; P286-W289 HydrophobicContact CB-CZ3 4.33Å; P286-W289 HydrophobicContact CG-CH2 4.08Å; P286-W289 HydrophobicContact CG-CZ2 3.93Å; P286-W289 PolarHBondContact O-N 3Å
287S95.2Very high96.4Very high101 Ų10163 Ų6371%0.70635%0.347SS*.G310 helixtrans-65.2-24.1176.385.40000113.3D285D285-S287 PolarHBondContact O-N 3.21Å; D285-S287 VanDerWaalsContact O-N 3.08Å; D285-S287 WeakPolarHBondContact OD1-CB 3.48Å; D285-S287 PolarHBondContact OD1-N 3.12Å; D285-S287 PolarHBondContact OD1-OG 3.44Å; D285-S287 PolarHBondContact OD2-OG 2.87Å
288G95Very high96.4Very high53 Ų5362.6 Ų62.655%0.54635%0.345SS..G310 helixtrans-91.2-8177.700000114.5D285 P286D285-G288 PolarHBondContact O-N 3.47Å; P286-G288 PolarHBondContact O-N 3.08Å
289W97.8Very high96.6Very high29 Ų2960 Ų6011%0.1133%0.331CS..  trans-70.4147.9-178.8-59.8-4.4000111.1K267 H269 L274 Y275 D276 D285 P286K267-W289 HydrophobicContact CB-CE3 4.23Å; K267-W289 HydrophobicContact CB-CH2 4.25Å; K267-W289 HydrophobicContact CB-CZ3 3.7Å; K267-W289 HydrophobicContact CD-CE3 4.42Å; K267-W289 HydrophobicContact CD-CH2 3.38Å; K267-W289 HydrophobicContact CD-CZ2 3.76Å; K267-W289 HydrophobicContact CD-CZ3 3.72Å; K267-W289 HydrophobicContact CG-CH2 4.44Å; K267-W289 HydrophobicContact CG-CZ3 4.34Å; H269-W289 HydrophobicContact CB-CE3 4.16Å; H269-W289 HydrophobicContact CB-CH2 4.49Å; H269-W289 HydrophobicContact CB-CZ3 3.56Å; H269-W289 AromaticContact CG-CZ3 3.94Å; L274-W289 HydrophobicContact CB-CB 4.01Å; L274-W289 HydrophobicContact CB-CE3 4.08Å; L274-W289 HydrophobicContact CD1-CB 4.24Å; L274-W289 HydrophobicContact CD1-CE3 4.09Å; Y275-W289 WeakPolarHBondContact O-CA 3.32Å; D276-W289 HydrophobicContact CB-CD2 3.97Å; D276-W289 HydrophobicContact CB-CG 4.01Å; D276-W289 HydrophobicContact CB-CZ2 4.38Å; D276-W289 PolarHBondContact OD1-NE1 3.16Å; D276-W289 PolarHBondContact OD2-NE1 3.1Å; D285-W289 VanDerWaalsContact O-CD1 3.26Å; D285-W289 PolarHBondContact O-NE1 3.45Å; P286-W289 HydrophobicContact CB-CD2 4.1Å; P286-W289 HydrophobicContact CB-CE3 4.18Å; P286-W289 HydrophobicContact CB-CH2 4.33Å; P286-W289 HydrophobicContact CB-CZ2 4.26Å; P286-W289 HydrophobicContact CB-CZ3 4.33Å; P286-W289 HydrophobicContact CG-CH2 4.08Å; P286-W289 HydrophobicContact CG-CZ2 3.93Å; P286-W289 PolarHBondContact O-N 3Å
290K98.2Very high96.7Very high61 Ų6162.2 Ų62.227%0.26534%0.341SS..BIsolated β-bridgetrans-103.5137.2-173.1-64.9-176.8-173.4-58.60110.7L274 Y275 L277 Q294 M295 L298L274-K290 CarbonylContact C-O 3.58Å; L274-K290 WeakPolarHBondContact CA-O 3.34Å; Y275-K290 WeakPolarHBondContact CD2-O 3.49Å; Y275-K290 PolarHBondContact N-O 2.86Å; Y275-K290 PolarHBondContact O-N 2.62Å; L277-K290 HydrophobicContact CD1-CD 3.88Å; K290-Q294 HydrophobicContact CB-CB 3.9Å; K290-Q294 HydrophobicContact CG-CB 4.24Å; K290-M295 HydrophobicContact CB-CG 3.94Å; K290-M295 HydrophobicContact CB-SD 3.7Å; K290-M295 HydrophobicContact CD-SD 3.7Å; K290-M295 HydrophobicContact CG-SD 4.28Å; K290-L298 HydrophobicContact CD-CD2 4.34Å
291N98Very high96.9Very high62 Ų6263.5 Ų63.533%0.33235%0.347SS..  trans-78.8174.8164.46930.7000110.8L274 D293 Q294 M295L274-N291 HydrophobicContact CD2-CB 3.93Å; N291-D293 VanDerWaalsContact C-N 3.33Å; N291-D293 PolarHBondContact O-N 2.72Å; N291-D293 PolarHBondContact OD1-N 3.32Å; N291-D293 VanDerWaalsContact OD1-N 3.1Å; N291-Q294 PolarHBondContact O-N 2.9Å; N291-Q294 WeakPolarHBondContact OD1-CG 3.48Å; N291-Q294 PolarHBondContact OD1-N 2.93Å; N291-M295 WeakPolarHBondContact O-CG 3.31Å; N291-M295 PolarHBondContact O-N 3.46Å
292G98Very high97.1Very high5 Ų561.1 Ų61.15%0.05233%0.334CS..Hα-helixtrans-59.2-37.2-179.100000114.9M295 L296G292-M295 PolarHBondContact O-N 3.21Å; G292-L296 WeakPolarHBondContact O-CB 3.42Å; G292-L296 PolarHBondContact O-N 3.15Å
293D98.2Very high97.4Very high80 Ų8056.7 Ų56.743%0.42830%0.303SS..Hα-helixtrans-68-39.2177.5-65.9-34.7000111N291 L296 D297 K325N291-D293 VanDerWaalsContact C-N 3.33Å; N291-D293 PolarHBondContact O-N 2.72Å; N291-D293 PolarHBondContact OD1-N 3.32Å; N291-D293 VanDerWaalsContact OD1-N 3.1Å; D293-L296 WeakPolarHBondContact O-CB 3.49Å; D293-L296 PolarHBondContact O-N 2.74Å; D293-D297 PolarHBondContact O-N 2.97Å; D293-K325 IonicContact OD1-NZ 2.9Å; D293-K325 PolarHBondContact OD1-NZ 3.07Å; D293-K325 IonicContact OD2-NZ 2.89Å
294Q98.4Very high97.5Very high90 Ų9052.6 Ų52.642%0.42130%0.298SS..Hα-helixtrans-67.2-34.7174.6-70.1172.3-51.500112.7K290 N291 L298K290-Q294 HydrophobicContact CB-CB 3.9Å; K290-Q294 HydrophobicContact CG-CB 4.24Å; N291-Q294 PolarHBondContact O-N 2.9Å; N291-Q294 WeakPolarHBondContact OD1-CG 3.48Å; N291-Q294 PolarHBondContact OD1-N 2.93Å; Q294-L298 WeakPolarHBondContact O-CB 3.41Å; Q294-L298 PolarHBondContact O-N 3.22Å; Q294-L298 VanDerWaalsContact O-N 3.1Å
295M98.5Very high97.6Very high0 Ų053.7 Ų53.70%031%0.308CS..Hα-helixtrans-66.9-43.6172.2-71.9-56.9-62.200111.2F265 Y275 L277 K290 N291 G292 D297 L298 Y299 F315F265-M295 HydrophobicContact CE2-CE 4.04Å; F265-M295 HydrophobicContact CZ-CE 4.33Å; Y275-M295 HydrophobicContact CD2-CG 3.49Å; Y275-M295 VanDerWaalsContact CD2-CG 3.49Å; Y275-M295 HydrophobicContact CE2-CG 4.2Å; Y275-M295 HydrophobicContact CG-CG 3.74Å; Y275-M295 HydrophobicContact CG-SD 4.3Å; L277-M295 HydrophobicContact CD1-SD 4.41Å; L277-M295 HydrophobicContact CD2-CE 4.09Å; L277-M295 HydrophobicContact CD2-SD 4.27Å; L277-M295 HydrophobicContact CG-SD 4.48Å; K290-M295 HydrophobicContact CB-CG 3.94Å; K290-M295 HydrophobicContact CB-SD 3.7Å; K290-M295 HydrophobicContact CD-SD 3.7Å; K290-M295 HydrophobicContact CG-SD 4.28Å; N291-M295 WeakPolarHBondContact O-CG 3.31Å; N291-M295 PolarHBondContact O-N 3.46Å; G292-M295 PolarHBondContact O-N 3.21Å; M295-D297 VanDerWaalsContact C-N 3.35Å; M295-D297 PolarHBondContact O-N 2.96Å; M295-L298 WeakPolarHBondContact O-CB 3.49Å; M295-L298 PolarHBondContact O-N 2.89Å; M295-L298 VanDerWaalsContact O-N 3.15Å; M295-Y299 HydrophobicContact CB-CE2 4.14Å; M295-Y299 HydrophobicContact CE-CE1 4.22Å; M295-Y299 HydrophobicContact CE-CE2 4.28Å; M295-Y299 WeakPolarHBondContact CE-OH 3.08Å; M295-Y299 WeakPolarHBondContact O-CD2 3.44Å; M295-Y299 PolarHBondContact O-N 3.27Å; M295-F315 HydrophobicContact CB-CD1 4.49Å; M295-F315 HydrophobicContact CB-CE1 3.85Å
296L98.5Very high97.7Very high12 Ų1249.6 Ų49.66%0.06329%0.285CS..Hα-helixtrans-58.6-45.2175.5-176.9154.9000111.8G292 D293 L298 Y299 K300 F315 K325 F326G292-L296 WeakPolarHBondContact O-CB 3.42Å; G292-L296 PolarHBondContact O-N 3.15Å; D293-L296 WeakPolarHBondContact O-CB 3.49Å; D293-L296 PolarHBondContact O-N 2.74Å; L296-L298 VanDerWaalsContact C-N 3.3Å; L296-L298 PolarHBondContact O-N 2.9Å; L296-Y299 PolarHBondContact O-N 2.95Å; L296-K300 HydrophobicContact CD2-CD 3.76Å; L296-K300 HydrophobicContact CD2-CG 4.28Å; L296-K300 VanDerWaalsContact CD2-NZ 3.32Å; L296-K300 PolarHBondContact O-N 3.25Å; L296-F315 HydrophobicContact CB-CZ 4.16Å; L296-K325 HydrophobicContact CD1-CB 3.82Å; L296-F326 HydrophobicContact CD1-CB 4.17Å; L296-F326 HydrophobicContact CG-CD2 4.18Å
297D98.3Very high97.8Very high96 Ų9650.2 Ų50.251%0.51329%0.289SS..Hα-helixtrans-64.2-35.9176.4-74.7-19.8000112.2D293 M295 K300 H301D293-D297 PolarHBondContact O-N 2.97Å; M295-D297 VanDerWaalsContact C-N 3.35Å; M295-D297 PolarHBondContact O-N 2.96Å; D297-K300 PolarHBondContact O-N 2.94Å; D297-H301 PolarHBondContact O-N 2.57Å
298L97.9Very high98Very high33 Ų3345.9 Ų45.917%0.17326%0.258CS..Hα-helixtrans-62.5-45.4173.8-173.366.7000111.4M179 L277 K290 Q294 M295 L296 H301 Y302M179-L298 HydrophobicContact CE-CD2 4.09Å; L277-L298 HydrophobicContact CD1-CD2 3.78Å; K290-L298 HydrophobicContact CD-CD2 4.34Å; Q294-L298 WeakPolarHBondContact O-CB 3.41Å; Q294-L298 PolarHBondContact O-N 3.22Å; Q294-L298 VanDerWaalsContact O-N 3.1Å; M295-L298 WeakPolarHBondContact O-CB 3.49Å; M295-L298 PolarHBondContact O-N 2.89Å; M295-L298 VanDerWaalsContact O-N 3.15Å; L296-L298 VanDerWaalsContact C-N 3.3Å; L296-L298 PolarHBondContact O-N 2.9Å; L298-H301 WeakPolarHBondContact O-CB 3.4Å; L298-H301 PolarHBondContact O-N 2.92Å; L298-Y302 HydrophobicContact CD1-CE1 4.1Å; L298-Y302 HydrophobicContact CD1-CE2 4.22Å; L298-Y302 WeakPolarHBondContact CD1-OH 3.44Å; L298-Y302 HydrophobicContact CD2-CE2 4.13Å; L298-Y302 HydrophobicContact CG-CD2 4.49Å; L298-Y302 HydrophobicContact CG-CE1 4.45Å; L298-Y302 HydrophobicContact CG-CE2 3.69Å; L298-Y302 WeakPolarHBondContact O-CD2 3.38Å; L298-Y302 PolarHBondContact O-N 3.4Å; L298-Y302 VanDerWaalsContact O-N 3.13Å
299Y98.6Very high98.2Very high0 Ų044.7 Ų44.70%024%0.24CC..Hα-helixtrans-62.9-45175.9-59-43.6000111.7M179 V260 M295 L296 H301 Y302 L303 I311 A314 F315 F326M179-Y299 HydrophobicContact CE-CE1 3.84Å; V260-Y299 HydrophobicContact CG1-CE1 4.45Å; V260-Y299 VanDerWaalsContact CG1-OH 3.24Å; V260-Y299 WeakPolarHBondContact CG1-OH 3.47Å; V260-Y299 HydrophobicContact CG2-CE1 3.82Å; M295-Y299 HydrophobicContact CB-CE2 4.14Å; M295-Y299 HydrophobicContact CE-CE1 4.22Å; M295-Y299 HydrophobicContact CE-CE2 4.28Å; M295-Y299 WeakPolarHBondContact CE-OH 3.08Å; M295-Y299 WeakPolarHBondContact O-CD2 3.44Å; M295-Y299 PolarHBondContact O-N 3.27Å; L296-Y299 PolarHBondContact O-N 2.95Å; Y299-H301 PolarHBondContact O-N 2.85Å; Y299-Y302 HydrophobicContact CD1-CD2 4.34Å; Y299-Y302 PolarHBondContact O-N 3.39Å; Y299-L303 VanDerWaalsContact O-CG 3.31Å; Y299-L303 WeakPolarHBondContact O-CG 3.41Å; Y299-L303 PolarHBondContact O-N 2.99Å; Y299-I311 HydrophobicContact CD1-CD1 4.39Å; Y299-A314 HydrophobicContact CD2-CB 4.35Å; Y299-A314 HydrophobicContact CE2-CB 3.84Å; Y299-A314 VanDerWaalsContact CE2-O 3.31Å; Y299-A314 WeakPolarHBondContact CE2-O 3.17Å; Y299-A314 PolarHBondContact OH-O 3.44Å; Y299-F315 HydrophobicContact CD2-CE2 4.49Å; Y299-F315 HydrophobicContact CD2-CZ 4.08Å; Y299-F315 HydrophobicContact CE2-CE1 4.17Å; Y299-F315 HydrophobicContact CE2-CE2 4.24Å; Y299-F315 AromaticContact CE2-CZ 3.86Å; Y299-F315 HydrophobicContact CE2-CZ 3.86Å; Y299-F326 HydrophobicContact CD2-CD2 4.48Å; Y299-F326 HydrophobicContact CD2-CE2 4.24Å; Y299-F326 HydrophobicContact CD2-CZ 4.35Å; Y299-F326 HydrophobicContact CG-CE2 4.35Å; Y299-F326 HydrophobicContact CG-CZ 4.37Å
300K98.2Very high98.2Very high90 Ų9043.4 Ų43.439%0.39124%0.236SC..Hα-helixtrans-56.4-40.6175.3-77.5179.8175.8165.70112.4L296 D297 L303 S304L296-K300 HydrophobicContact CD2-CD 3.76Å; L296-K300 HydrophobicContact CD2-CG 4.28Å; L296-K300 VanDerWaalsContact CD2-NZ 3.32Å; L296-K300 PolarHBondContact O-N 3.25Å; D297-K300 PolarHBondContact O-N 2.94Å; K300-L303 PolarHBondContact O-N 3.18Å; K300-S304 WeakPolarHBondContact O-CB 3.38Å; K300-S304 PolarHBondContact O-N 3.16Å
301H97.9Very high98.2Very high94 Ų9440.5 Ų40.544%0.43522%0.223SC..Hα-helixtrans-58.7-48.1174.7-178.965.7000111.1D297 L298 Y299 S304 A305D297-H301 PolarHBondContact O-N 2.57Å; L298-H301 WeakPolarHBondContact O-CB 3.4Å; L298-H301 PolarHBondContact O-N 2.92Å; Y299-H301 PolarHBondContact O-N 2.85Å; H301-S304 PolarHBondContact O-N 3.16Å; H301-S304 PolarHBondContact O-OG 3.4Å; H301-A305 WeakPolarHBondContact O-CB 3.26Å; H301-A305 PolarHBondContact O-N 3.07Å; H301-A305 VanDerWaalsContact O-N 3.17Å
302Y98.3Very high98.3Very high5 Ų537.6 Ų37.62%0.0221%0.207CC..Hα-helixtrans-62.3-44.8176.9-57.8-32.1000112.8M179 P234 K235 L238 M258 L298 Y299 S304 A305 Y306M179-Y302 HydrophobicContact CE-CE2 3.81Å; M179-Y302 HydrophobicContact SD-CE2 4.18Å; P234-Y302 HydrophobicContact CB-CE2 4.28Å; P234-Y302 WeakPolarHBondContact CB-OH 3.46Å; K235-Y302 HydrophobicContact CB-CE1 4.34Å; L238-Y302 HydrophobicContact CD1-CD1 3.81Å; L238-Y302 HydrophobicContact CD1-CD2 4.31Å; L238-Y302 HydrophobicContact CD1-CE1 4.34Å; L238-Y302 HydrophobicContact CD1-CG 3.81Å; M258-Y302 HydrophobicContact CE-CD2 4.26Å; M258-Y302 HydrophobicContact CE-CE2 4.47Å; L298-Y302 HydrophobicContact CD1-CE1 4.1Å; L298-Y302 HydrophobicContact CD1-CE2 4.22Å; L298-Y302 WeakPolarHBondContact CD1-OH 3.44Å; L298-Y302 HydrophobicContact CD2-CE2 4.13Å; L298-Y302 HydrophobicContact CG-CD2 4.49Å; L298-Y302 HydrophobicContact CG-CE1 4.45Å; L298-Y302 HydrophobicContact CG-CE2 3.69Å; L298-Y302 WeakPolarHBondContact O-CD2 3.38Å; L298-Y302 PolarHBondContact O-N 3.4Å; L298-Y302 VanDerWaalsContact O-N 3.13Å; Y299-Y302 HydrophobicContact CD1-CD2 4.34Å; Y299-Y302 PolarHBondContact O-N 3.39Å; Y302-S304 PolarHBondContact O-N 3.08Å; Y302-A305 PolarHBondContact O-N 2.7Å; Y302-A305 VanDerWaalsContact O-N 3.08Å; Y302-Y306 HydrophobicContact CD1-CE2 4.49Å; Y302-Y306 WeakPolarHBondContact O-CD2 3.45Å; Y302-Y306 PolarHBondContact O-N 3.38Å
303L98.3Very high98.3Very high38 Ų3837.4 Ų37.420%0.19921%0.205CC..Hα-helixtrans-60.2-31.8177.9-63.1-174.5000112.6Y299 K300 I308 I311 F326 T330 I332Y299-L303 VanDerWaalsContact O-CG 3.31Å; Y299-L303 WeakPolarHBondContact O-CG 3.41Å; Y299-L303 PolarHBondContact O-N 2.99Å; K300-L303 PolarHBondContact O-N 3.18Å; L303-I308 HydrophobicContact CD2-CB 3.72Å; L303-I308 HydrophobicContact CD2-CD1 4.45Å; L303-I308 HydrophobicContact CD2-CG2 3.61Å; L303-I311 HydrophobicContact CD2-CD1 3.87Å; L303-I311 HydrophobicContact CG-CD1 4.48Å; L303-F326 HydrophobicContact CD1-CE2 4.36Å; L303-F326 HydrophobicContact CD1-CZ 4.38Å; L303-T330 VanDerWaalsContact CD1-OG1 3.24Å; L303-T330 WeakPolarHBondContact CD1-OG1 3.44Å; L303-I332 HydrophobicContact CD1-CD1 4.26Å; L303-I332 HydrophobicContact CD1-CG1 4.32Å; L303-I332 HydrophobicContact CD1-CG2 4.49Å; L303-I332 HydrophobicContact CD2-CD1 3.67Å; L303-I332 HydrophobicContact CD2-CG1 4.41Å; L303-I332 HydrophobicContact CD2-CG2 4.24Å
304S97.7Very high98.3Very high97 Ų9733.6 Ų33.668%0.67819%0.185SC*.Hα-helixtrans-76.7-27.3176.576.70000113.8K300 H301 Y302K300-S304 WeakPolarHBondContact O-CB 3.38Å; K300-S304 PolarHBondContact O-N 3.16Å; H301-S304 PolarHBondContact O-N 3.16Å; H301-S304 PolarHBondContact O-OG 3.4Å; Y302-S304 PolarHBondContact O-N 3.08Å
305A97.6Very high98.3Very high40 Ų4029.3 Ų29.333%0.33117%0.165SC..Hα-helixtrans-100.3-22.9-171.800000113.8H301 Y302H301-A305 WeakPolarHBondContact O-CB 3.26Å; H301-A305 PolarHBondContact O-N 3.07Å; H301-A305 VanDerWaalsContact O-N 3.17Å; Y302-A305 PolarHBondContact O-N 2.7Å; Y302-A305 VanDerWaalsContact O-N 3.08Å
306Y98.3Very high98.3Very high12 Ų1230.4 Ų30.45%0.04717%0.17CC..SBendtrans-133.7151.7-172.2-56.9-80.4000111.6K235 L238 D239 K242 Y302 I308K235-Y306 HydrophobicContact CG-CE2 4.29Å; K235-Y306 WeakPolarHBondContact CG-OH 3.33Å; K235-Y306 PolarHBondContact NZ-OH 2.94Å; L238-Y306 HydrophobicContact CB-CD1 3.69Å; L238-Y306 HydrophobicContact CB-CD2 3.9Å; L238-Y306 HydrophobicContact CB-CE1 3.56Å; L238-Y306 HydrophobicContact CB-CE2 3.78Å; L238-Y306 HydrophobicContact CB-CG 3.87Å; L238-Y306 HydrophobicContact CD1-CD2 3.6Å; L238-Y306 HydrophobicContact CD1-CE2 3.76Å; L238-Y306 HydrophobicContact CD1-CG 4.18Å; L238-Y306 HydrophobicContact CG-CD2 4.26Å; L238-Y306 HydrophobicContact CG-CE2 4.4Å; L238-Y306 HydrophobicContact CG-CG 4.42Å; D239-Y306 VanDerWaalsContact CG-OH 3.24Å; D239-Y306 VanDerWaalsContact OD1-CE1 3.29Å; D239-Y306 WeakPolarHBondContact OD1-CE1 3.47Å; D239-Y306 PolarHBondContact OD1-OH 3.49Å; K242-Y306 HydrophobicContact CD-CD1 4.42Å; K242-Y306 HydrophobicContact CD-CE1 4.43Å; Y302-Y306 HydrophobicContact CD1-CE2 4.49Å; Y302-Y306 WeakPolarHBondContact O-CD2 3.45Å; Y302-Y306 PolarHBondContact O-N 3.38Å; Y306-I308 PolarHBondContact O-N 3.42Å
307P97.2Very high98.2Very high57 Ų5730.5 Ų30.537%0.3717%0.17SC..  trans-77.156179.335-37.8000111.5K255 I256K255-P307 WeakPolarHBondContact CB-O 3.4Å; K255-P307 HydrophobicContact CD-CB 4.19Å; I256-P307 HydrophobicContact CD1-CG 4.43Å; I256-P307 PolarHBondContact N-O 3.11Å
308I98.6Very high98.1Very high9 Ų928.6 Ų28.65%0.04616%0.16CC..EExtended strand (participates in β ladder)trans-80.4127.8178.5-63.8161.3000108.9L238 I256 M258 L303 Y306 I311 I332L238-I308 HydrophobicContact CD1-CD1 4.18Å; L238-I308 HydrophobicContact CD2-CD1 4.05Å; L238-I308 HydrophobicContact CD2-CG1 4.35Å; I256-I308 HydrophobicContact CB-CG1 4.07Å; I256-I308 HydrophobicContact CG2-CG1 3.98Å; I256-I308 CarbonylContact O-C 3.54Å; I256-I308 VanDerWaalsContact O-CA 3.26Å; I256-I308 WeakPolarHBondContact O-CA 3.25Å; M258-I308 HydrophobicContact SD-CD1 3.63Å; M258-I308 HydrophobicContact SD-CG1 4.34Å; L303-I308 HydrophobicContact CD2-CB 3.72Å; L303-I308 HydrophobicContact CD2-CD1 4.45Å; L303-I308 HydrophobicContact CD2-CG2 3.61Å; Y306-I308 PolarHBondContact O-N 3.42Å; I308-I311 HydrophobicContact CG2-CD1 4.16Å; I308-I311 HydrophobicContact CG2-CG1 3.81Å; I308-I332 HydrophobicContact CG2-CD1 4.35Å
309V98.6Very high98.1Very high29 Ų2927.6 Ų27.618%0.17616%0.155CC..EExtended strand (participates in β ladder)trans-118.9-8.5-179-63.50000113.6M185 K255 I256 Q333 F449M185-V309 HydrophobicContact SD-CG2 3.97Å; K255-V309 HydrophobicContact CB-CB 4.32Å; K255-V309 HydrophobicContact CB-CG1 3.79Å; K255-V309 HydrophobicContact CB-CG2 3.57Å; K255-V309 HydrophobicContact CD-CG1 4.15Å; K255-V309 HydrophobicContact CG-CG1 3.77Å; K255-V309 HydrophobicContact CG-CG2 4.19Å; I256-V309 PolarHBondContact O-N 2.78Å; V309-Q333 WeakPolarHBondContact O-CB 3.29Å; V309-Q333 PolarHBondContact O-N 3Å; V309-F449 HydrophobicContact CB-CZ 4.16Å; V309-F449 HydrophobicContact CG2-CZ 4Å
310S98.8Very high98.1Very high1 Ų128.9 Ų28.91%0.00716%0.16CC..EExtended strand (participates in β ladder)trans-149.6133.4178.7-1720000111.5A257 M258 Q333 V335A257-S310 CarbonylContact C-O 3.13Å; A257-S310 VanDerWaalsContact CA-O 3.23Å; A257-S310 WeakPolarHBondContact CA-O 3.25Å; M258-S310 PolarHBondContact N-O 2.48Å; S310-Q333 CarbonylContact C-O 3.44Å; S310-Q333 VanDerWaalsContact CA-O 3.28Å; S310-Q333 WeakPolarHBondContact CA-O 3.15Å; S310-Q333 PolarHBondContact OG-NE2 3.03Å; S310-V335 VanDerWaalsContact OG-CG2 3.27Å; S310-V335 WeakPolarHBondContact OG-CG2 3.34Å
311I98.9Very high98.1Very high0 Ų030.4 Ų30.40%017%0.172CC..EExtended strand (participates in β ladder)trans-127.5126170.4-65.8-179.4000108.5M258 V260 Y299 L303 I308 A314 F326 I332 Q333 V334 V335M258-I311 HydrophobicContact CB-CG1 4.43Å; M258-I311 CarbonylContact O-C 3.56Å; M258-I311 WeakPolarHBondContact O-CA 3.48Å; V260-I311 HydrophobicContact CG2-CG2 3.92Å; Y299-I311 HydrophobicContact CD1-CD1 4.39Å; L303-I311 HydrophobicContact CD2-CD1 3.87Å; L303-I311 HydrophobicContact CG-CD1 4.48Å; I308-I311 HydrophobicContact CG2-CD1 4.16Å; I308-I311 HydrophobicContact CG2-CG1 3.81Å; I311-A314 HydrophobicContact CG2-CB 3.87Å; I311-F326 HydrophobicContact CB-CE1 4.45Å; I311-F326 HydrophobicContact CD1-CZ 4.06Å; I311-F326 HydrophobicContact CG2-CE1 4.46Å; I311-I332 HydrophobicContact CB-CD1 4.01Å; I311-I332 HydrophobicContact CD1-CD1 3.96Å; I311-I332 HydrophobicContact CG1-CD1 3.66Å; I311-Q333 PolarHBondContact N-O 3.29Å; I311-V334 CarbonylContact O-C 3.59Å; I311-V334 WeakPolarHBondContact O-CA 3.44Å; I311-V335 PolarHBondContact O-N 2.79Å
312E98.8Very high98.1Very high1 Ų126.9 Ų26.91%0.00516%0.156CC..EExtended strand (participates in β ladder)trans-104140.6177.4176.4-176.2158.600110.1M258 D259 V260 A314 V335 D337 L360 K413M258-E312 PolarHBondContact O-N 3.29Å; D259-E312 HydrophobicContact CB-CB 4.12Å; D259-E312 HydrophobicContact CB-CG 4.23Å; V260-E312 PolarHBondContact N-O 2.9Å; E312-A314 VanDerWaalsContact C-N 3.32Å; E312-A314 PolarHBondContact O-N 3.26Å; E312-V335 HydrophobicContact CB-CB 3.84Å; E312-V335 HydrophobicContact CB-CG1 4.43Å; E312-V335 HydrophobicContact CB-CG2 4.36Å; E312-V335 HydrophobicContact CG-CB 4.15Å; E312-V335 HydrophobicContact CG-CG1 4.24Å; E312-D337 HydrophobicContact CG-CB 4.2Å; E312-L360 WeakPolarHBondContact OE1-CD2 3.11Å; E312-K413 IonicContact OE1-NZ 3.52Å; E312-K413 PolarHBondContact OE1-NZ 3.04Å; E312-K413 IonicContact OE2-NZ 3.59Å; E312-K413 PolarHBondContact OE2-NZ 3.29Å
313D98.4Very high98.1Very high2 Ų226.6 Ų26.61%0.01116%0.155CC..  trans46.849.1175.4-75.44.2000115.2V260 A262 F315 V335 D337 D338V260-D313 WeakPolarHBondContact CB-O 3.3Å; A262-D313 VanDerWaalsContact CB-O 3.26Å; A262-D313 WeakPolarHBondContact CB-O 3.34Å; A262-D313 PolarHBondContact N-O 3.05Å; D313-F315 PolarHBondContact O-N 2.9Å; D313-V335 PolarHBondContact N-O 3.25Å; D313-D337 PolarHBondContact OD1-N 3.05Å; D313-D337 WeakPolarHBondContact OD2-CB 3.43Å; D313-D338 PolarHBondContact OD1-N 3.45Å; D313-D338 WeakPolarHBondContact OD2-CB 3.29Å; D313-D338 PolarHBondContact OD2-N 2.93Å
314A98.5Very high98.1Very high0 Ų026.2 Ų26.20%016%0.157CC..  trans-62.1-24.4-178.300000114.1Y299 I311 E312 F326Y299-A314 HydrophobicContact CD2-CB 4.35Å; Y299-A314 HydrophobicContact CE2-CB 3.84Å; Y299-A314 VanDerWaalsContact CE2-O 3.31Å; Y299-A314 WeakPolarHBondContact CE2-O 3.17Å; Y299-A314 PolarHBondContact OH-O 3.44Å; I311-A314 HydrophobicContact CG2-CB 3.87Å; E312-A314 VanDerWaalsContact C-N 3.32Å; E312-A314 PolarHBondContact O-N 3.26Å; A314-F326 HydrophobicContact CB-CD1 4.07Å; A314-F326 HydrophobicContact CB-CE1 4.09Å
315F98.7Very high98.2Very high0 Ų026 Ų260%014%0.144CC..SBendtrans-139.1167.3179.5-58-83.6000109.7Y275 M295 L296 Y299 D313 D319 N322 W323 F326Y275-F315 HydrophobicContact CE2-CD1 4.29Å; Y275-F315 WeakPolarHBondContact OH-CB 3.27Å; M295-F315 HydrophobicContact CB-CD1 4.49Å; M295-F315 HydrophobicContact CB-CE1 3.85Å; L296-F315 HydrophobicContact CB-CZ 4.16Å; Y299-F315 HydrophobicContact CD2-CE2 4.49Å; Y299-F315 HydrophobicContact CD2-CZ 4.08Å; Y299-F315 HydrophobicContact CE2-CE1 4.17Å; Y299-F315 HydrophobicContact CE2-CE2 4.24Å; Y299-F315 AromaticContact CE2-CZ 3.86Å; Y299-F315 HydrophobicContact CE2-CZ 3.86Å; D313-F315 PolarHBondContact O-N 2.9Å; F315-D319 HydrophobicContact CB-CB 4.22Å; F315-N322 HydrophobicContact CD1-CB 3.57Å; F315-N322 HydrophobicContact CD2-CB 4.31Å; F315-N322 HydrophobicContact CE1-CB 3.73Å; F315-N322 HydrophobicContact CE2-CB 4.47Å; F315-N322 WeakPolarHBondContact CE2-O 3.5Å; F315-N322 HydrophobicContact CG-CB 3.88Å; F315-N322 HydrophobicContact CZ-CB 4.19Å; F315-W323 HydrophobicContact CB-CG 4.29Å; F315-W323 HydrophobicContact CD2-CD2 4.31Å; F315-W323 HydrophobicContact CD2-CG 4.23Å; F315-W323 PolarHBondContact O-NE1 3.09Å; F315-F326 HydrophobicContact CD2-CB 4.47Å; F315-F326 HydrophobicContact CE2-CB 3.41Å; F315-F326 VanDerWaalsContact CE2-CB 3.41Å; F315-F326 AromaticContact CE2-CD1 3.98Å; F315-F326 HydrophobicContact CE2-CD1 3.98Å; F315-F326 AromaticContact CE2-CG 3.79Å; F315-F326 HydrophobicContact CE2-CG 3.79Å; F315-F326 HydrophobicContact CZ-CB 3.93Å; F315-F326 HydrophobicContact CZ-CG 4.3Å
316E98Very high98.2Very high22 Ų2224.1 Ų24.110%0.10313%0.129CC..  trans-56.1144.2175.1-171.5-84.3161.500110.6F266 Y275 D318 D319 W323F266-E316 HydrophobicContact CB-CB 3.92Å; F266-E316 HydrophobicContact CB-CG 3.84Å; F266-E316 HydrophobicContact CD1-CB 4.33Å; F266-E316 HydrophobicContact CD1-CG 3.74Å; F266-E316 HydrophobicContact CD2-CB 3.61Å; F266-E316 HydrophobicContact CD2-CG 3.98Å; F266-E316 HydrophobicContact CE1-CG 4.24Å; F266-E316 HydrophobicContact CE2-CB 4.11Å; F266-E316 HydrophobicContact CE2-CG 4.41Å; F266-E316 HydrophobicContact CG-CB 3.7Å; F266-E316 HydrophobicContact CG-CG 3.58Å; Y275-E316 HydrophobicContact CE1-CB 4.16Å; Y275-E316 PolarHBondContact OH-N 3.43Å; E316-D318 PolarHBondContact O-N 3.08Å; E316-D318 WeakPolarHBondContact OE2-CA 3.41Å; E316-D318 PolarHBondContact OE2-N 3.48Å; E316-D319 HydrophobicContact CB-CB 4.18Å; E316-D319 WeakPolarHBondContact O-CB 3.46Å; E316-D319 PolarHBondContact O-N 3.05Å; E316-D319 PolarHBondContact OE2-N 3.41Å; E316-D319 VanDerWaalsContact OE2-N 3.09Å; E316-W323 PolarHBondContact O-NE1 3.16Å
317Q97.1Very high98.2Very high14 Ų1425 Ų257%0.06513%0.134CC..THydrogen-bonded Turntrans-58.2-13.1-169.868.7-161.8-18.800116.1G56 I57 S263 D338 L339 R346G56-Q317 VanDerWaalsContact CA-OE1 3.27Å; I57-Q317 VanDerWaalsContact CD1-NE2 3.34Å; I57-Q317 VanDerWaalsContact CG1-NE2 3.29Å; I57-Q317 VanDerWaalsContact CG2-NE2 3.35Å; I57-Q317 VanDerWaalsContact N-OE1 3.08Å; S263-Q317 PolarHBondContact OG-N 2.98Å; S263-Q317 VanDerWaalsContact OG-N 3.14Å; Q317-D338 HydrophobicContact CB-CB 3.79Å; Q317-L339 VanDerWaalsContact O-CD1 3.23Å; Q317-L339 WeakPolarHBondContact O-CD1 3.4Å; Q317-R346 PolarHBondContact O-NH2 2.79Å
318D96.8Very high98.3Very high56 Ų5631.6 Ų31.630%0.29916%0.157SC..THydrogen-bonded Turntrans-123.99.3173.7-77.2-34.4000113.3H58 E316 W320 R346H58-D318 IonicContact NE2-OD1 2.6Å; H58-D318 IonicContact NE2-OD2 3.92Å; E316-D318 PolarHBondContact O-N 3.08Å; E316-D318 WeakPolarHBondContact OE2-CA 3.41Å; E316-D318 PolarHBondContact OE2-N 3.48Å; D318-W320 PolarHBondContact O-N 3.11Å; D318-W320 PolarHBondContact OD1-NE1 2.91Å; D318-R346 IonicContact OD1-CZ 3.67Å; D318-R346 IonicContact OD1-NH1 3.79Å; D318-R346 IonicContact OD1-NH2 2.73Å; D318-R346 PolarHBondContact OD1-NH2 3Å
319D96.9Very high98.2Very high12 Ų1233.2 Ų33.26%0.06417%0.169CC..  trans-80.353172.4-166.31.8000112.1Y275 F315 E316 D321 N322 W323Y275-D319 PolarHBondContact OH-OD2 3.33Å; F315-D319 HydrophobicContact CB-CB 4.22Å; E316-D319 HydrophobicContact CB-CB 4.18Å; E316-D319 WeakPolarHBondContact O-CB 3.46Å; E316-D319 PolarHBondContact O-N 3.05Å; E316-D319 PolarHBondContact OE2-N 3.41Å; E316-D319 VanDerWaalsContact OE2-N 3.09Å; D319-D321 PolarHBondContact O-N 2.95Å; D319-D321 VanDerWaalsContact O-N 3.07Å; D319-N322 PolarHBondContact O-N 3.07Å; D319-N322 VanDerWaalsContact O-N 3.1Å; D319-N322 PolarHBondContact OD1-ND2 3.31Å; D319-N322 PolarHBondContact OD2-ND2 3.48Å; D319-W323 VanDerWaalsContact O-CD1 3.28Å; D319-W323 PolarHBondContact O-N 2.97Å
320W98Very high98.2Very high27 Ų2732.9 Ų32.910%0.10217%0.167CC..Hα-helixtrans-51.4-35.3-172.4-66.899.1000114.3D318 A324 L339 T349 A350 K353 A355D318-W320 PolarHBondContact O-N 3.11Å; D318-W320 PolarHBondContact OD1-NE1 2.91Å; W320-A324 WeakPolarHBondContact O-CB 3.2Å; W320-A324 PolarHBondContact O-N 3.28Å; W320-L339 HydrophobicContact CD2-CD1 4.15Å; W320-L339 HydrophobicContact CE3-CD1 3.71Å; W320-L339 HydrophobicContact CH2-CD1 3.54Å; W320-L339 HydrophobicContact CH2-CG 4Å; W320-L339 HydrophobicContact CZ2-CD1 3.99Å; W320-L339 HydrophobicContact CZ3-CD1 3.37Å; W320-L339 HydrophobicContact CZ3-CD2 4.17Å; W320-L339 HydrophobicContact CZ3-CG 3.86Å; W320-T349 HydrophobicContact CH2-CG2 3.78Å; W320-T349 HydrophobicContact CZ2-CG2 3.84Å; W320-T349 HydrophobicContact CZ3-CG2 4.24Å; W320-A350 HydrophobicContact CH2-CB 4.08Å; W320-A350 HydrophobicContact CZ3-CB 3.67Å; W320-K353 HydrophobicContact CB-CD 3.84Å; W320-K353 HydrophobicContact CD2-CD 3.52Å; W320-K353 HydrophobicContact CE3-CB 4.22Å; W320-K353 HydrophobicContact CE3-CD 3.54Å; W320-K353 HydrophobicContact CE3-CG 4.47Å; W320-K353 HydrophobicContact CG-CD 3.66Å; W320-K353 HydrophobicContact CZ3-CD 4.31Å; W320-A355 HydrophobicContact CE3-CB 3.7Å; W320-A355 HydrophobicContact CZ3-CB 3.83Å
321D97.9Very high98.1Very high123 Ų12340 Ų4066%0.65821%0.205SC*.Hα-helixtrans-67.8-43-177.6-70.8-14.7000111.3D319 A324 K325D319-D321 PolarHBondContact O-N 2.95Å; D319-D321 VanDerWaalsContact O-N 3.07Å; D321-A324 PolarHBondContact O-N 3.34Å; D321-K325 WeakPolarHBondContact O-CB 3.46Å; D321-K325 VanDerWaalsContact O-CG 3.29Å; D321-K325 WeakPolarHBondContact O-CG 2.71Å; D321-K325 PolarHBondContact O-N 3.23Å
322N98.5Very high98.1Very high19 Ų1941.2 Ų41.210%0.10221%0.211CC..Hα-helixtrans-74.3-35.1179.1-68.5-45000112F315 D319 A324 K325 F326F315-N322 HydrophobicContact CD1-CB 3.57Å; F315-N322 HydrophobicContact CD2-CB 4.31Å; F315-N322 HydrophobicContact CE1-CB 3.73Å; F315-N322 HydrophobicContact CE2-CB 4.47Å; F315-N322 WeakPolarHBondContact CE2-O 3.5Å; F315-N322 HydrophobicContact CG-CB 3.88Å; F315-N322 HydrophobicContact CZ-CB 4.19Å; D319-N322 PolarHBondContact O-N 3.07Å; D319-N322 VanDerWaalsContact O-N 3.1Å; D319-N322 PolarHBondContact OD1-ND2 3.31Å; D319-N322 PolarHBondContact OD2-ND2 3.48Å; N322-A324 PolarHBondContact O-N 3.21Å; N322-K325 PolarHBondContact O-N 2.93Å; N322-K325 PolarHBondContact OD1-NZ 3.38Å; N322-F326 WeakPolarHBondContact O-CB 3.4Å; N322-F326 PolarHBondContact O-N 2.86Å
323W98.7Very high98Very high0 Ų041.2 Ų41.20%021%0.211CC..Hα-helixtrans-54.1-52.1167.2-82.3100.8000111.9F315 E316 D319 F326 L327 V334 V335 L339 A355 C356F315-W323 HydrophobicContact CB-CG 4.29Å; F315-W323 HydrophobicContact CD2-CD2 4.31Å; F315-W323 HydrophobicContact CD2-CG 4.23Å; F315-W323 PolarHBondContact O-NE1 3.09Å; E316-W323 PolarHBondContact O-NE1 3.16Å; D319-W323 VanDerWaalsContact O-CD1 3.28Å; D319-W323 PolarHBondContact O-N 2.97Å; W323-F326 PolarHBondContact O-N 3.2Å; W323-L327 PolarHBondContact O-N 3.46Å; W323-V334 HydrophobicContact CE3-CG1 3.86Å; W323-V334 HydrophobicContact CZ3-CG1 3.66Å; W323-V335 WeakPolarHBondContact CH2-O 3.27Å; W323-L339 HydrophobicContact CD2-CD1 4.45Å; W323-L339 HydrophobicContact CD2-CD2 3.8Å; W323-L339 HydrophobicContact CE3-CD2 3.91Å; W323-L339 HydrophobicContact CG-CD1 4.38Å; W323-L339 HydrophobicContact CG-CD2 4.27Å; W323-L339 HydrophobicContact CH2-CB 4.34Å; W323-L339 HydrophobicContact CH2-CD2 4.24Å; W323-L339 HydrophobicContact CZ2-CB 3.96Å; W323-L339 HydrophobicContact CZ2-CD2 4.2Å; W323-L339 HydrophobicContact CZ3-CD2 4.11Å; W323-A355 CarbonylContact C-O 3.53Å; W323-A355 HydrophobicContact CB-CB 3.88Å; W323-C356 HydrophobicContact CE3-CB 4.22Å; W323-C356 HydrophobicContact CZ3-CB 4.08Å
324A98.6Very high98.1Very high29 Ų2941.1 Ų41.124%0.2421%0.211CC..Hα-helixtrans-65.9-40.2-178.900000113.1W320 D321 N322 F326 K328 K354W320-A324 WeakPolarHBondContact O-CB 3.2Å; W320-A324 PolarHBondContact O-N 3.28Å; D321-A324 PolarHBondContact O-N 3.34Å; N322-A324 PolarHBondContact O-N 3.21Å; A324-F326 VanDerWaalsContact C-N 3.32Å; A324-F326 PolarHBondContact O-N 2.94Å; A324-K328 WeakPolarHBondContact O-CB 3.34Å; A324-K328 PolarHBondContact O-N 3.19Å; A324-K328 VanDerWaalsContact O-N 3.12Å; A324-K354 WeakPolarHBondContact CA-O 3.4Å
325K98.5Very high98.1Very high93 Ų9341.1 Ų41.140%0.40421%0.211SC..Hα-helixtrans-58.6-45172.4-76.6174.1-178.7177.30111.2D293 L296 D321 N322 K328 S329D293-K325 IonicContact OD1-NZ 2.9Å; D293-K325 PolarHBondContact OD1-NZ 3.07Å; D293-K325 IonicContact OD2-NZ 2.89Å; L296-K325 HydrophobicContact CD1-CB 3.82Å; D321-K325 WeakPolarHBondContact O-CB 3.46Å; D321-K325 VanDerWaalsContact O-CG 3.29Å; D321-K325 WeakPolarHBondContact O-CG 2.71Å; D321-K325 PolarHBondContact O-N 3.23Å; N322-K325 PolarHBondContact O-N 2.93Å; N322-K325 PolarHBondContact OD1-NZ 3.38Å; K325-K328 PolarHBondContact O-N 2.8Å; K325-S329 WeakPolarHBondContact O-CB 3.47Å; K325-S329 PolarHBondContact O-N 3.32Å
326F98.7Very high98.1Very high0 Ų041.1 Ų41.10%021%0.211CC..Hα-helixtrans-67.8-47.6-177.8-178.5-124.4000111.9L296 Y299 L303 I311 A314 F315 N322 W323 A324 K328 S329 T330 V334L296-F326 HydrophobicContact CD1-CB 4.17Å; L296-F326 HydrophobicContact CG-CD2 4.18Å; Y299-F326 HydrophobicContact CD2-CD2 4.48Å; Y299-F326 HydrophobicContact CD2-CE2 4.24Å; Y299-F326 HydrophobicContact CD2-CZ 4.35Å; Y299-F326 HydrophobicContact CG-CE2 4.35Å; Y299-F326 HydrophobicContact CG-CZ 4.37Å; L303-F326 HydrophobicContact CD1-CE2 4.36Å; L303-F326 HydrophobicContact CD1-CZ 4.38Å; I311-F326 HydrophobicContact CB-CE1 4.45Å; I311-F326 HydrophobicContact CD1-CZ 4.06Å; I311-F326 HydrophobicContact CG2-CE1 4.46Å; A314-F326 HydrophobicContact CB-CD1 4.07Å; A314-F326 HydrophobicContact CB-CE1 4.09Å; F315-F326 HydrophobicContact CD2-CB 4.47Å; F315-F326 HydrophobicContact CE2-CB 3.41Å; F315-F326 VanDerWaalsContact CE2-CB 3.41Å; F315-F326 AromaticContact CE2-CD1 3.98Å; F315-F326 HydrophobicContact CE2-CD1 3.98Å; F315-F326 AromaticContact CE2-CG 3.79Å; F315-F326 HydrophobicContact CE2-CG 3.79Å; F315-F326 HydrophobicContact CZ-CB 3.93Å; F315-F326 HydrophobicContact CZ-CG 4.3Å; N322-F326 WeakPolarHBondContact O-CB 3.4Å; N322-F326 PolarHBondContact O-N 2.86Å; W323-F326 PolarHBondContact O-N 3.2Å; A324-F326 VanDerWaalsContact C-N 3.32Å; A324-F326 PolarHBondContact O-N 2.94Å; F326-K328 VanDerWaalsContact C-N 3.25Å; F326-K328 PolarHBondContact O-N 3.33Å; F326-S329 WeakPolarHBondContact CA-OG 3.2Å; F326-S329 WeakPolarHBondContact O-CA 3.48Å; F326-S329 WeakPolarHBondContact O-CB 3.35Å; F326-S329 PolarHBondContact O-N 3Å; F326-S329 PolarHBondContact O-OG 2.77Å; F326-T330 HydrophobicContact CE1-CG2 4.38Å; F326-T330 HydrophobicContact CE2-CG2 4.19Å; F326-T330 HydrophobicContact CZ-CG2 4.1Å; F326-T330 WeakPolarHBondContact O-CG2 3.43Å; F326-T330 PolarHBondContact O-N 2.91Å; F326-V334 HydrophobicContact CD1-CG1 4.19Å; F326-V334 HydrophobicContact CD1-CG2 4.07Å; F326-V334 HydrophobicContact CE1-CG1 4.41Å; F326-V334 HydrophobicContact CE1-CG2 3.88Å
327L98.5Very high98.1Very high31 Ų3140.3 Ų40.316%0.16221%0.207CC..Hα-helixtrans-56.2-40.6176.3-179.266.1000111.8W323 S329 T330 V334 K354 C356 N357W323-L327 PolarHBondContact O-N 3.46Å; L327-S329 PolarHBondContact O-N 2.98Å; L327-T330 VanDerWaalsContact O-O 3.07Å; L327-V334 HydrophobicContact CD1-CB 4.08Å; L327-V334 HydrophobicContact CD1-CG2 3.96Å; L327-K354 HydrophobicContact CD2-CB 4.32Å; L327-K354 WeakPolarHBondContact CD2-O 3.33Å; L327-C356 WeakPolarHBondContact CD2-O 3.26Å; L327-N357 HydrophobicContact CD1-CB 3.82Å; L327-N357 WeakPolarHBondContact CD1-ND2 3.5Å
328K98.3Very high98.1Very high195 Ų19539.8 Ų39.885%0.84821%0.205SC*.Hα-helixtrans-66.7-22.8176.3-174.2177.2176.9-175.10113.2A324 K325 F326A324-K328 WeakPolarHBondContact O-CB 3.34Å; A324-K328 PolarHBondContact O-N 3.19Å; A324-K328 VanDerWaalsContact O-N 3.12Å; K325-K328 PolarHBondContact O-N 2.8Å; F326-K328 VanDerWaalsContact C-N 3.25Å; F326-K328 PolarHBondContact O-N 3.33Å
329S98Very high98.1Very high44 Ų4437.1 Ų37.131%0.30819%0.191SC..THydrogen-bonded Turntrans-94.4-2.7-172.977.90000114.7K325 F326 L327K325-S329 WeakPolarHBondContact O-CB 3.47Å; K325-S329 PolarHBondContact O-N 3.32Å; F326-S329 WeakPolarHBondContact CA-OG 3.2Å; F326-S329 WeakPolarHBondContact O-CA 3.48Å; F326-S329 WeakPolarHBondContact O-CB 3.35Å; F326-S329 PolarHBondContact O-N 3Å; F326-S329 PolarHBondContact O-OG 2.77Å; L327-S329 PolarHBondContact O-N 2.98Å
330T97.8Very high98.2Very high22 Ų2236.5 Ų36.514%0.13519%0.187CC..  trans-146.9153.2-174.7-167.70000112.4L303 F326 L327 I332 V334L303-T330 VanDerWaalsContact CD1-OG1 3.24Å; L303-T330 WeakPolarHBondContact CD1-OG1 3.44Å; F326-T330 HydrophobicContact CE1-CG2 4.38Å; F326-T330 HydrophobicContact CE2-CG2 4.19Å; F326-T330 HydrophobicContact CZ-CG2 4.1Å; F326-T330 WeakPolarHBondContact O-CG2 3.43Å; F326-T330 PolarHBondContact O-N 2.91Å; L327-T330 VanDerWaalsContact O-O 3.07Å; T330-I332 HydrophobicContact CG2-CG1 3.77Å; T330-I332 WeakPolarHBondContact OG1-CG1 3.38Å; T330-I332 PolarHBondContact OG1-N 3.48Å; T330-V334 HydrophobicContact CG2-CG2 3.91Å
331D96.4Very high98.1Very high150 Ų15035.2 Ų35.280%0.80218%0.183SC*.  trans-98.8-4.4176.6-63.7-47.6000113R450D331-R450 PolarHBondContact O-NH1 2.94Å
332I98.3Very high98.1Very high26 Ų2629.4 Ų29.413%0.13315%0.151CC..SBendtrans-69.2172.4-178.671.7151.9000111.9L303 I308 I311 T330 V334 N357L303-I332 HydrophobicContact CD1-CD1 4.26Å; L303-I332 HydrophobicContact CD1-CG1 4.32Å; L303-I332 HydrophobicContact CD1-CG2 4.49Å; L303-I332 HydrophobicContact CD2-CD1 3.67Å; L303-I332 HydrophobicContact CD2-CG1 4.41Å; L303-I332 HydrophobicContact CD2-CG2 4.24Å; I308-I332 HydrophobicContact CG2-CD1 4.35Å; I311-I332 HydrophobicContact CB-CD1 4.01Å; I311-I332 HydrophobicContact CD1-CD1 3.96Å; I311-I332 HydrophobicContact CG1-CD1 3.66Å; T330-I332 HydrophobicContact CG2-CG1 3.77Å; T330-I332 WeakPolarHBondContact OG1-CG1 3.38Å; T330-I332 PolarHBondContact OG1-N 3.48Å; I332-V334 HydrophobicContact CG1-CG2 4.5Å; I332-V334 PolarHBondContact O-N 2.86Å; I332-N357 PolarHBondContact O-ND2 2.85Å
333Q98.7Very high97.9Very high0 Ų030.3 Ų30.30%016%0.156CC..EExtended strand (participates in β ladder)trans-69.8126.3167.3-174.3171.1-91.300110.1V309 S310 I311 V335 N357 C358V309-Q333 WeakPolarHBondContact O-CB 3.29Å; V309-Q333 PolarHBondContact O-N 3Å; S310-Q333 CarbonylContact C-O 3.44Å; S310-Q333 VanDerWaalsContact CA-O 3.28Å; S310-Q333 WeakPolarHBondContact CA-O 3.15Å; S310-Q333 PolarHBondContact OG-NE2 3.03Å; I311-Q333 PolarHBondContact N-O 3.29Å; Q333-V335 HydrophobicContact CG-CG2 3.8Å; Q333-N357 WeakPolarHBondContact CA-OD1 3.3Å; Q333-C358 HydrophobicContact CG-CB 3.37Å; Q333-C358 PolarHBondContact OE1-SG 3.08Å
334V98.8Very high97.7Very high0 Ų032.2 Ų32.20%017%0.168CC..EExtended strand (participates in β ladder)trans-114108.81731790000106I311 W323 F326 L327 T330 I332 C356 N357 C358I311-V334 CarbonylContact O-C 3.59Å; I311-V334 WeakPolarHBondContact O-CA 3.44Å; W323-V334 HydrophobicContact CE3-CG1 3.86Å; W323-V334 HydrophobicContact CZ3-CG1 3.66Å; F326-V334 HydrophobicContact CD1-CG1 4.19Å; F326-V334 HydrophobicContact CD1-CG2 4.07Å; F326-V334 HydrophobicContact CE1-CG1 4.41Å; F326-V334 HydrophobicContact CE1-CG2 3.88Å; L327-V334 HydrophobicContact CD1-CB 4.08Å; L327-V334 HydrophobicContact CD1-CG2 3.96Å; T330-V334 HydrophobicContact CG2-CG2 3.91Å; I332-V334 HydrophobicContact CG1-CG2 4.5Å; I332-V334 PolarHBondContact O-N 2.86Å; V334-C356 HydrophobicContact CG1-CB 4.03Å; V334-C356 WeakPolarHBondContact O-CB 3.27Å; V334-N357 PolarHBondContact N-OD1 2.83Å; V334-N357 PolarHBondContact O-N 3.28Å; V334-N357 PolarHBondContact O-OD1 2.82Å; V334-C358 PolarHBondContact O-N 3.48Å
335V98.9Very high97.5Very high0 Ų037.2 Ų37.20%019%0.185CC..EExtended strand (participates in β ladder)trans-96.1125.8-172-169.50000109.2S310 I311 E312 D313 W323 Q333 C358 L360S310-V335 VanDerWaalsContact OG-CG2 3.27Å; S310-V335 WeakPolarHBondContact OG-CG2 3.34Å; I311-V335 PolarHBondContact O-N 2.79Å; E312-V335 HydrophobicContact CB-CB 3.84Å; E312-V335 HydrophobicContact CB-CG1 4.43Å; E312-V335 HydrophobicContact CB-CG2 4.36Å; E312-V335 HydrophobicContact CG-CB 4.15Å; E312-V335 HydrophobicContact CG-CG1 4.24Å; D313-V335 PolarHBondContact N-O 3.25Å; W323-V335 WeakPolarHBondContact CH2-O 3.27Å; Q333-V335 HydrophobicContact CG-CG2 3.8Å; V335-C358 WeakPolarHBondContact CA-O 3.16Å; V335-C358 HydrophobicContact CB-CB 4.39Å; V335-C358 HydrophobicContact CG1-CB 4.47Å; V335-C358 HydrophobicContact CG2-CB 4.02Å; V335-L360 HydrophobicContact CG1-CB 3.7Å; V335-L360 HydrophobicContact CG1-CD1 4Å; V335-L360 HydrophobicContact CG1-CG 4.47Å
336G98.5Very high97.5Very high0 Ų034.3 Ų34.30%017%0.171CC..EExtended strand (participates in β ladder)trans-96.6113.8169.400000110.7T340 C358 L360G336-T340 PolarHBondContact O-OG1 2.87Å; G336-C358 PolarHBondContact N-O 2.77Å; G336-L360 PolarHBondContact O-N 2.92Å
337D98.2Very high97.4Very high5 Ų534.3 Ų34.33%0.02717%0.171CC..SBendtrans-101.7-81.7170.9178.328.3000109.9E312 D313 L339 T340 C341 L360 K362 Q365E312-D337 HydrophobicContact CG-CB 4.2Å; D313-D337 PolarHBondContact OD1-N 3.05Å; D313-D337 WeakPolarHBondContact OD2-CB 3.43Å; D337-L339 PolarHBondContact O-N 3.05Å; D337-T340 CarbonylContact O-C 3.51Å; D337-T340 PolarHBondContact O-N 3.18Å; D337-T340 PolarHBondContact O-OG1 3.2Å; D337-C341 PolarHBondContact O-N 2.81Å; D337-L360 HydrophobicContact CB-CB 3.79Å; D337-L360 HydrophobicContact CB-CD2 3.66Å; D337-L360 HydrophobicContact CB-CG 4.37Å; D337-L360 WeakPolarHBondContact OD2-CD2 3.27Å; D337-K362 IonicContact OD1-NZ 2.8Å; D337-K362 IonicContact OD2-NZ 3.2Å; D337-K362 PolarHBondContact OD2-NZ 3.36Å; D337-Q365 PolarHBondContact OD1-NE2 2.85Å; D337-Q365 PolarHBondContact OD1-OE1 3.29Å
338D96.8Very high97.4Very high3 Ų335.6 Ų35.62%0.01618%0.176CC..THydrogen-bonded Turntrans-61.3-31.4178.6-74.4-15.4000112.1G56 D313 Q317 T340 C341G56-D338 VanDerWaalsContact CA-OD1 3.3Å; G56-D338 WeakPolarHBondContact CA-OD1 3.16Å; G56-D338 PolarHBondContact N-OD1 2.97Å; D313-D338 PolarHBondContact OD1-N 3.45Å; D313-D338 WeakPolarHBondContact OD2-CB 3.29Å; D313-D338 PolarHBondContact OD2-N 2.93Å; Q317-D338 HydrophobicContact CB-CB 3.79Å; D338-T340 PolarHBondContact O-N 2.91Å; D338-C341 PolarHBondContact O-SG 2.9Å
339L97.6Very high97.4Very high0 Ų028.9 Ų28.90%015%0.152CC..THydrogen-bonded Turntrans-55.2-37.8173.1-17670.5000112.1Q317 W320 W323 D337 R346 A350 A355 C356Q317-L339 VanDerWaalsContact O-CD1 3.23Å; Q317-L339 WeakPolarHBondContact O-CD1 3.4Å; W320-L339 HydrophobicContact CD2-CD1 4.15Å; W320-L339 HydrophobicContact CE3-CD1 3.71Å; W320-L339 HydrophobicContact CH2-CD1 3.54Å; W320-L339 HydrophobicContact CH2-CG 4Å; W320-L339 HydrophobicContact CZ2-CD1 3.99Å; W320-L339 HydrophobicContact CZ3-CD1 3.37Å; W320-L339 HydrophobicContact CZ3-CD2 4.17Å; W320-L339 HydrophobicContact CZ3-CG 3.86Å; W323-L339 HydrophobicContact CD2-CD1 4.45Å; W323-L339 HydrophobicContact CD2-CD2 3.8Å; W323-L339 HydrophobicContact CE3-CD2 3.91Å; W323-L339 HydrophobicContact CG-CD1 4.38Å; W323-L339 HydrophobicContact CG-CD2 4.27Å; W323-L339 HydrophobicContact CH2-CB 4.34Å; W323-L339 HydrophobicContact CH2-CD2 4.24Å; W323-L339 HydrophobicContact CZ2-CB 3.96Å; W323-L339 HydrophobicContact CZ2-CD2 4.2Å; W323-L339 HydrophobicContact CZ3-CD2 4.11Å; D337-L339 PolarHBondContact O-N 3.05Å; L339-R346 PolarHBondContact O-NE 3.16Å; L339-R346 PolarHBondContact O-NH2 2.99Å; L339-A350 HydrophobicContact CD2-CB 4.23Å; L339-A355 HydrophobicContact CD2-CB 3.88Å; L339-C356 HydrophobicContact CD2-CB 4.17Å
340T98Very high97.5Very high0 Ų026.8 Ų26.80%014%0.137CC..THydrogen-bonded Turntrans-113.4-27.7-171.272.70000113.9G336 D337 D338 T342 N343 R346 I347 A350 L359 W384G336-T340 PolarHBondContact O-OG1 2.87Å; D337-T340 CarbonylContact O-C 3.51Å; D337-T340 PolarHBondContact O-N 3.18Å; D337-T340 PolarHBondContact O-OG1 3.2Å; D338-T340 PolarHBondContact O-N 2.91Å; T340-T342 PolarHBondContact O-N 3.45Å; T340-T342 VanDerWaalsContact O-N 3.12Å; T340-N343 WeakPolarHBondContact O-CB 3.36Å; T340-N343 PolarHBondContact O-N 3.05Å; T340-R346 WeakPolarHBondContact O-CB 3.39Å; T340-I347 HydrophobicContact CG2-CG1 4.33Å; T340-A350 HydrophobicContact CG2-CB 4.18Å; T340-L359 WeakPolarHBondContact OG1-CD1 3.34Å; T340-W384 HydrophobicContact CG2-CZ3 4.45Å
341C96.6Very high97.5Very high0 Ų027.3 Ų27.30%014%0.139CC..THydrogen-bonded Turntrans49.231.3-178.3-65.70000113.7H58 E59 D337 D338 N343 Q365H58-C341 HydrophobicContact CB-CB 4.48Å; E59-C341 HydrophobicContact CG-CB 4.25Å; D337-C341 PolarHBondContact O-N 2.81Å; D338-C341 PolarHBondContact O-SG 2.9Å; C341-N343 PolarHBondContact O-N 3.01Å; C341-Q365 VanDerWaalsContact C-OE1 3.26Å; C341-Q365 WeakPolarHBondContact O-CB 3.47Å
342T97.6Very high97.6Very high0 Ų025.3 Ų25.30%013%0.128CC..THydrogen-bonded Turntrans53.819.2-171-48.70000113.4T340 L360 L361 K362 Q365 I366 A375T340-T342 PolarHBondContact O-N 3.45Å; T340-T342 VanDerWaalsContact O-N 3.12Å; T342-L360 PolarHBondContact OG1-O 2.86Å; T342-L361 HydrophobicContact CG2-CG 3.98Å; T342-K362 PolarHBondContact OG1-N 3.3Å; T342-K362 PolarHBondContact OG1-O 3.03Å; T342-Q365 PolarHBondContact OG1-OE1 2.9Å; T342-I366 HydrophobicContact CG2-CB 4.01Å; T342-I366 HydrophobicContact CG2-CG2 3.76Å; T342-A375 HydrophobicContact CG2-CB 3.84Å; T342-A375 WeakPolarHBondContact O-CB 3.4Å
343N95.5Very high97.6Very high38 Ų3828.7 Ų28.720%0.20314%0.142CC..  trans-96.6117.7-174-177.4-34.5000110.6T340 C341 K345 R346 I347 I366T340-N343 WeakPolarHBondContact O-CB 3.36Å; T340-N343 PolarHBondContact O-N 3.05Å; C341-N343 PolarHBondContact O-N 3.01Å; N343-K345 PolarHBondContact O-N 3.46Å; N343-K345 WeakPolarHBondContact OD1-CB 3.49Å; N343-K345 PolarHBondContact OD1-N 2.94Å; N343-R346 HydrophobicContact CB-CB 4.37Å; N343-R346 HydrophobicContact CB-CG 4.47Å; N343-R346 PolarHBondContact O-N 2.73Å; N343-I347 VanDerWaalsContact O-CG1 3.3Å; N343-I347 WeakPolarHBondContact O-CG1 3.35Å; N343-I347 PolarHBondContact O-N 3.04Å; N343-I366 HydrophobicContact CB-CD1 4.39Å
344P93.9Very high97.6Very high40 Ų4036 Ų3626%0.2617%0.174SC..Hα-helixtrans-52.7-32.1-178.8-28.936000115.2Q348 A375P344-Q348 WeakPolarHBondContact O-CB 3.25Å; P344-Q348 PolarHBondContact O-N 3.06Å; P344-A375 HydrophobicContact CG-CB 4.4Å
345K94.9Very high97.5Very high134 Ų13436 Ų3658%0.58317%0.174SC*.Hα-helixtrans-68.8-45.6176.8-62.7-177.2-174.2176.10111.5E115 N343 Q348 T349E115-K345 IonicContact OE1-NZ 2.72Å; E115-K345 PolarHBondContact OE1-NZ 3.2Å; N343-K345 PolarHBondContact O-N 3.46Å; N343-K345 WeakPolarHBondContact OD1-CB 3.49Å; N343-K345 PolarHBondContact OD1-N 2.94Å; K345-Q348 WeakPolarHBondContact O-CB 3.47Å; K345-Q348 PolarHBondContact O-N 3.3Å; K345-T349 PolarHBondContact O-N 2.8Å; K345-T349 VanDerWaalsContact O-N 3.1Å; K345-T349 PolarHBondContact O-OG1 2.79Å
346R97.1Very high97.5Very high32 Ų3236 Ų3612%0.12117%0.174CC..Hα-helixtrans-71.8-36.2178.2-68.9-165.26889.7-4.7111.8H58 Q317 D318 L339 T340 N343 Q348 T349 A350H58-R346 PolarHBondContact CD2-NH1 2.98Å; H58-R346 PolarHBondContact CE1-NH1 2.9Å; H58-R346 PolarHBondContact NE2-NH1 3.17Å; Q317-R346 PolarHBondContact O-NH2 2.79Å; D318-R346 IonicContact OD1-CZ 3.67Å; D318-R346 IonicContact OD1-NH1 3.79Å; D318-R346 IonicContact OD1-NH2 2.73Å; D318-R346 PolarHBondContact OD1-NH2 3Å; L339-R346 PolarHBondContact O-NE 3.16Å; L339-R346 PolarHBondContact O-NH2 2.99Å; T340-R346 WeakPolarHBondContact O-CB 3.39Å; N343-R346 HydrophobicContact CB-CB 4.37Å; N343-R346 HydrophobicContact CB-CG 4.47Å; N343-R346 PolarHBondContact O-N 2.73Å; R346-Q348 VanDerWaalsContact C-N 3.3Å; R346-Q348 PolarHBondContact O-N 2.96Å; R346-T349 WeakPolarHBondContact O-CB 3.4Å; R346-T349 PolarHBondContact O-N 3.18Å; R346-A350 WeakPolarHBondContact O-CB 3.12Å; R346-A350 PolarHBondContact O-N 3.45Å
347I98.3Very high97.5Very high0 Ų037.3 Ų37.30%018%0.181CC..Hα-helixtrans-56-47.2170.3-66.8165.5000109.9T340 N343 T349 A350 I351 L359 A375 K378 W384T340-I347 HydrophobicContact CG2-CG1 4.33Å; N343-I347 VanDerWaalsContact O-CG1 3.3Å; N343-I347 WeakPolarHBondContact O-CG1 3.35Å; N343-I347 PolarHBondContact O-N 3.04Å; I347-T349 PolarHBondContact O-N 3.17Å; I347-A350 PolarHBondContact O-N 2.59Å; I347-I351 HydrophobicContact CG2-CD1 3.73Å; I347-I351 HydrophobicContact CG2-CG1 4.44Å; I347-I351 WeakPolarHBondContact O-CD1 3.37Å; I347-I351 VanDerWaalsContact O-CG1 3.26Å; I347-I351 WeakPolarHBondContact O-CG1 3.28Å; I347-I351 PolarHBondContact O-N 3.18Å; I347-L359 HydrophobicContact CD1-CD1 3.89Å; I347-L359 HydrophobicContact CD1-CD2 3.83Å; I347-L359 HydrophobicContact CD1-CG 4.48Å; I347-L359 HydrophobicContact CG1-CD1 4.12Å; I347-A375 HydrophobicContact CD1-CB 3.72Å; I347-K378 HydrophobicContact CG2-CB 4.44Å; I347-K378 HydrophobicContact CG2-CG 3.89Å; I347-W384 HydrophobicContact CG2-CZ3 4.19Å
348Q98Very high97.6Very high58 Ų5837 Ų3727%0.27118%0.18SC..Hα-helixtrans-57.9-48.4175.3-17861.86200111.9P344 K345 R346 A350 I351 D352P344-Q348 WeakPolarHBondContact O-CB 3.25Å; P344-Q348 PolarHBondContact O-N 3.06Å; K345-Q348 WeakPolarHBondContact O-CB 3.47Å; K345-Q348 PolarHBondContact O-N 3.3Å; R346-Q348 VanDerWaalsContact C-N 3.3Å; R346-Q348 PolarHBondContact O-N 2.96Å; Q348-A350 VanDerWaalsContact C-N 3.29Å; Q348-A350 PolarHBondContact O-N 2.99Å; Q348-I351 WeakPolarHBondContact O-CB 3.41Å; Q348-I351 PolarHBondContact O-N 3.3Å; Q348-D352 PolarHBondContact NE2-OD1 2.84Å; Q348-D352 PolarHBondContact NE2-OD2 3.27Å; Q348-D352 VanDerWaalsContact NE2-OD2 3.1Å; Q348-D352 VanDerWaalsContact O-CG 3.24Å; Q348-D352 PolarHBondContact O-N 2.69Å
349T98.3Very high97.6Very high54 Ų5436.9 Ų36.933%0.33118%0.179SC..Hα-helixtrans-57.7-42.5176.3-56.70000112.1W320 K345 R346 I347 D352 K353W320-T349 HydrophobicContact CH2-CG2 3.78Å; W320-T349 HydrophobicContact CZ2-CG2 3.84Å; W320-T349 HydrophobicContact CZ3-CG2 4.24Å; K345-T349 PolarHBondContact O-N 2.8Å; K345-T349 VanDerWaalsContact O-N 3.1Å; K345-T349 PolarHBondContact O-OG1 2.79Å; R346-T349 WeakPolarHBondContact O-CB 3.4Å; R346-T349 PolarHBondContact O-N 3.18Å; I347-T349 PolarHBondContact O-N 3.17Å; T349-D352 PolarHBondContact O-N 3.15Å; T349-K353 HydrophobicContact CG2-CD 4.03Å; T349-K353 HydrophobicContact CG2-CG 4.4Å; T349-K353 WeakPolarHBondContact O-CB 3.35Å; T349-K353 WeakPolarHBondContact O-CG 3.34Å; T349-K353 PolarHBondContact O-N 3.05Å
350A98.6Very high97.7Very high0 Ų036.9 Ų36.90%018%0.179CC..Hα-helixtrans-69.6-32.9-179.800000112.9W320 L339 T340 R346 I347 Q348 K354 A355 W384W320-A350 HydrophobicContact CH2-CB 4.08Å; W320-A350 HydrophobicContact CZ3-CB 3.67Å; L339-A350 HydrophobicContact CD2-CB 4.23Å; T340-A350 HydrophobicContact CG2-CB 4.18Å; R346-A350 WeakPolarHBondContact O-CB 3.12Å; R346-A350 PolarHBondContact O-N 3.45Å; I347-A350 PolarHBondContact O-N 2.59Å; Q348-A350 VanDerWaalsContact C-N 3.29Å; Q348-A350 PolarHBondContact O-N 2.99Å; A350-K354 WeakPolarHBondContact O-CA 3.33Å; A350-K354 PolarHBondContact O-N 3.26Å; A350-A355 HydrophobicContact CB-CB 4.3Å; A350-A355 PolarHBondContact O-N 2.9Å; A350-W384 HydrophobicContact CB-CH2 3.63Å; A350-W384 HydrophobicContact CB-CZ2 4.49Å; A350-W384 HydrophobicContact CB-CZ3 4.49Å
351I98.3Very high97.7Very high34 Ų3437 Ų3717%0.17418%0.179CC..Hα-helixtrans-63.1-51.6168.8-68.2156000110.1I347 Q348 K353 K354 K378 S382 W384I347-I351 HydrophobicContact CG2-CD1 3.73Å; I347-I351 HydrophobicContact CG2-CG1 4.44Å; I347-I351 WeakPolarHBondContact O-CD1 3.37Å; I347-I351 VanDerWaalsContact O-CG1 3.26Å; I347-I351 WeakPolarHBondContact O-CG1 3.28Å; I347-I351 PolarHBondContact O-N 3.18Å; Q348-I351 WeakPolarHBondContact O-CB 3.41Å; Q348-I351 PolarHBondContact O-N 3.3Å; I351-K353 VanDerWaalsContact C-N 3.31Å; I351-K353 PolarHBondContact O-N 3.14Å; I351-K354 PolarHBondContact O-N 2.97Å; I351-K378 HydrophobicContact CD1-CG 4.42Å; I351-S382 WeakPolarHBondContact CD1-OG 3.23Å; I351-W384 HydrophobicContact CB-CZ2 4.17Å; I351-W384 HydrophobicContact CG1-CD2 4.37Å; I351-W384 HydrophobicContact CG1-CH2 3.78Å; I351-W384 HydrophobicContact CG1-CZ2 3.44Å; I351-W384 VanDerWaalsContact CG1-CZ2 3.44Å; I351-W384 HydrophobicContact CG1-CZ3 4.37Å
352D98.4Very high97.8Very high108 Ų10837.9 Ų37.958%0.57818%0.183SC*.Hα-helixtrans-62.9-39.7-175.9-66.2-27000111.9Q348 T349 K354Q348-D352 PolarHBondContact NE2-OD1 2.84Å; Q348-D352 PolarHBondContact NE2-OD2 3.27Å; Q348-D352 VanDerWaalsContact NE2-OD2 3.1Å; Q348-D352 VanDerWaalsContact O-CG 3.24Å; Q348-D352 PolarHBondContact O-N 2.69Å; T349-D352 PolarHBondContact O-N 3.15Å; D352-K354 VanDerWaalsContact C-N 3.31Å
353K98.3Very high97.8Very high97 Ų9738.1 Ų38.142%0.42218%0.184SC..THydrogen-bonded Turntrans-81.6-6.8177.4-67.5-171.9174.4-162.70114W320 T349 I351 A355W320-K353 HydrophobicContact CB-CD 3.84Å; W320-K353 HydrophobicContact CD2-CD 3.52Å; W320-K353 HydrophobicContact CE3-CB 4.22Å; W320-K353 HydrophobicContact CE3-CD 3.54Å; W320-K353 HydrophobicContact CE3-CG 4.47Å; W320-K353 HydrophobicContact CG-CD 3.66Å; W320-K353 HydrophobicContact CZ3-CD 4.31Å; T349-K353 HydrophobicContact CG2-CD 4.03Å; T349-K353 HydrophobicContact CG2-CG 4.4Å; T349-K353 WeakPolarHBondContact O-CB 3.35Å; T349-K353 WeakPolarHBondContact O-CG 3.34Å; T349-K353 PolarHBondContact O-N 3.05Å; I351-K353 VanDerWaalsContact C-N 3.31Å; I351-K353 PolarHBondContact O-N 3.14Å; K353-A355 VanDerWaalsContact C-N 3.3Å; K353-A355 HydrophobicContact CB-CB 4.49Å; K353-A355 PolarHBondContact O-N 3.13Å
354K98.2Very high97.9Very high152 Ų15236.5 Ų36.566%0.66118%0.176SC*.THydrogen-bonded Turntrans51.949.6-174.3-54.9179.1-179-179.60111.6A324 L327 A350 I351 D352A324-K354 WeakPolarHBondContact CA-O 3.4Å; L327-K354 HydrophobicContact CD2-CB 4.32Å; L327-K354 WeakPolarHBondContact CD2-O 3.33Å; A350-K354 WeakPolarHBondContact O-CA 3.33Å; A350-K354 PolarHBondContact O-N 3.26Å; I351-K354 PolarHBondContact O-N 2.97Å; D352-K354 VanDerWaalsContact C-N 3.31Å
355A98.5Very high98Very high0 Ų034.7 Ų34.70%016%0.164CC..  trans-87.1-35.4-172.300000112.9W320 W323 L339 A350 K353W320-A355 HydrophobicContact CE3-CB 3.7Å; W320-A355 HydrophobicContact CZ3-CB 3.83Å; W323-A355 CarbonylContact C-O 3.53Å; W323-A355 HydrophobicContact CB-CB 3.88Å; L339-A355 HydrophobicContact CD2-CB 3.88Å; A350-A355 HydrophobicContact CB-CB 4.3Å; A350-A355 PolarHBondContact O-N 2.9Å; K353-A355 VanDerWaalsContact C-N 3.3Å; K353-A355 HydrophobicContact CB-CB 4.49Å; K353-A355 PolarHBondContact O-N 3.13Å
356C98.6Very high98.1Very high1 Ų128.7 Ų28.71%0.00714%0.138CC..  trans-145.6177177.665.60000110.7W323 L327 V334 L339 W384W323-C356 HydrophobicContact CE3-CB 4.22Å; W323-C356 HydrophobicContact CZ3-CB 4.08Å; L327-C356 WeakPolarHBondContact CD2-O 3.26Å; V334-C356 HydrophobicContact CG1-CB 4.03Å; V334-C356 WeakPolarHBondContact O-CB 3.27Å; L339-C356 HydrophobicContact CD2-CB 4.17Å; C356-W384 VanDerWaalsContact O-CE2 3.28Å; C356-W384 WeakPolarHBondContact O-CZ2 3.26Å; C356-W384 PolarHBondContact O-NE1 2.87Å; C356-W384 WeakPolarHBondContact SG-CH2 3.42Å; C356-W384 WeakPolarHBondContact SG-CZ3 3.42Å
357N98.5Very high98.1Very high27 Ų2727.1 Ų27.114%0.14413%0.132CC..SBendtrans-134.310.8179.267.821.3000113.6L327 I332 Q333 V334 W384 G385 R450L327-N357 HydrophobicContact CD1-CB 3.82Å; L327-N357 WeakPolarHBondContact CD1-ND2 3.5Å; I332-N357 PolarHBondContact O-ND2 2.85Å; Q333-N357 WeakPolarHBondContact CA-OD1 3.3Å; V334-N357 PolarHBondContact N-OD1 2.83Å; V334-N357 PolarHBondContact O-N 3.28Å; V334-N357 PolarHBondContact O-OD1 2.82Å; N357-W384 VanDerWaalsContact O-CA 3.25Å; N357-W384 WeakPolarHBondContact O-CA 3.45Å; N357-W384 WeakPolarHBondContact O-CB 3.24Å; N357-G385 PolarHBondContact O-N 2.91Å; N357-G385 VanDerWaalsContact O-N 3.08Å; N357-R450 PolarHBondContact ND2-NH2 3.31Å; N357-R450 VanDerWaalsContact ND2-NH2 3.19Å
358C98.7Very high98.1Very high0 Ų027.1 Ų27.10%013%0.132CC..EExtended strand (participates in β ladder)trans-146.7140.2174.8-179.70000110.2Q333 V334 V335 G336 G385Q333-C358 HydrophobicContact CG-CB 3.37Å; Q333-C358 PolarHBondContact OE1-SG 3.08Å; V334-C358 PolarHBondContact O-N 3.48Å; V335-C358 WeakPolarHBondContact CA-O 3.16Å; V335-C358 HydrophobicContact CB-CB 4.39Å; V335-C358 HydrophobicContact CG1-CB 4.47Å; V335-C358 HydrophobicContact CG2-CB 4.02Å; G336-C358 PolarHBondContact N-O 2.77Å; C358-G385 VanDerWaalsContact CA-O 3.27Å; C358-G385 WeakPolarHBondContact CA-O 3.23Å; C358-G385 VanDerWaalsContact SG-C 3.55Å; C358-G385 PolarHBondContact SG-O 3.14Å
359L98.7Very high98.2Very high0 Ų024.4 Ų24.40%012%0.12CC..EExtended strand (participates in β ladder)trans-93.9127.3172.3168.564.1000109.6T340 I347 L361 A375 A379 G385 V386 M387T340-L359 WeakPolarHBondContact OG1-CD1 3.34Å; I347-L359 HydrophobicContact CD1-CD1 3.89Å; I347-L359 HydrophobicContact CD1-CD2 3.83Å; I347-L359 HydrophobicContact CD1-CG 4.48Å; I347-L359 HydrophobicContact CG1-CD1 4.12Å; L359-L361 HydrophobicContact CD2-CB 4.42Å; L359-L361 HydrophobicContact CG-CB 4.42Å; L359-A375 HydrophobicContact CD2-CB 4.17Å; L359-A379 HydrophobicContact CB-CB 3.9Å; L359-A379 HydrophobicContact CD2-CB 3.98Å; L359-G385 PolarHBondContact N-O 3.3Å; L359-V386 HydrophobicContact CB-CG2 4.37Å; L359-V386 HydrophobicContact CD2-CG1 4.36Å; L359-V386 HydrophobicContact CG-CG1 4.49Å; L359-V386 CarbonylContact O-C 3.54Å; L359-V386 WeakPolarHBondContact O-CA 3.38Å; L359-M387 PolarHBondContact O-N 3.24Å
360L98.7Very high98.2Very high0 Ų022.6 Ų22.60%011%0.109CC..EExtended strand (participates in β ladder)trans-79.9116.2157.7-157.181.2000108.6E312 V335 G336 D337 T342 K362 M387 K413E312-L360 WeakPolarHBondContact OE1-CD2 3.11Å; V335-L360 HydrophobicContact CG1-CB 3.7Å; V335-L360 HydrophobicContact CG1-CD1 4Å; V335-L360 HydrophobicContact CG1-CG 4.47Å; G336-L360 PolarHBondContact O-N 2.92Å; D337-L360 HydrophobicContact CB-CB 3.79Å; D337-L360 HydrophobicContact CB-CD2 3.66Å; D337-L360 HydrophobicContact CB-CG 4.37Å; D337-L360 WeakPolarHBondContact OD2-CD2 3.27Å; T342-L360 PolarHBondContact OG1-O 2.86Å; L360-K362 HydrophobicContact CD2-CD 3.87Å; L360-K362 HydrophobicContact CD2-CG 4.19Å; L360-M387 CarbonylContact C-O 3.6Å; L360-M387 WeakPolarHBondContact CA-O 3.39Å; L360-M387 HydrophobicContact CD1-CB 4.03Å; L360-M387 HydrophobicContact CD1-CG 3.89Å; L360-M387 HydrophobicContact CD1-SD 3.73Å; L360-K413 HydrophobicContact CD1-CD 4.25Å
361L98.7Very high98.2Very high1 Ų124 Ų241%0.00512%0.115CC..EExtended strand (participates in β ladder)trans-97.5109.1-179.3-172.6161.2000109.4T342 L359 V363 C376 V386 M387 V388 S389 L403 L407T342-L361 HydrophobicContact CG2-CG 3.98Å; L359-L361 HydrophobicContact CD2-CB 4.42Å; L359-L361 HydrophobicContact CG-CB 4.42Å; L361-V363 HydrophobicContact CD2-CG1 4.15Å; L361-C376 HydrophobicContact CD1-CB 3.69Å; L361-V386 HydrophobicContact CB-CG1 3.79Å; L361-V386 HydrophobicContact CD1-CG1 3.99Å; L361-M387 PolarHBondContact N-O 3.26Å; L361-V388 HydrophobicContact CD2-CG2 4.45Å; L361-S389 PolarHBondContact O-N 2.84Å; L361-L403 HydrophobicContact CD2-CD2 3.79Å; L361-L407 HydrophobicContact CD1-CD1 3.88Å
362K98.2Very high98.2Very high19 Ų1922.4 Ų22.48%0.08311%0.107CC..  trans-117.4113.6173.8-74.6169.91671640109.1D337 T342 L360 N364 Q365 H390D337-K362 IonicContact OD1-NZ 2.8Å; D337-K362 IonicContact OD2-NZ 3.2Å; D337-K362 PolarHBondContact OD2-NZ 3.36Å; T342-K362 PolarHBondContact OG1-N 3.3Å; T342-K362 PolarHBondContact OG1-O 3.03Å; L360-K362 HydrophobicContact CD2-CD 3.87Å; L360-K362 HydrophobicContact CD2-CG 4.19Å; K362-N364 PolarHBondContact O-N 3.23Å; K362-N364 VanDerWaalsContact O-N 3.1Å; K362-Q365 HydrophobicContact CB-CB 4.28Å; K362-Q365 HydrophobicContact CB-CG 3.64Å; K362-Q365 HydrophobicContact CD-CG 4.14Å; K362-Q365 WeakPolarHBondContact O-CB 3.33Å; K362-Q365 PolarHBondContact O-N 3.47Å; K362-H390 VanDerWaalsContact CE-O 3.25Å; K362-H390 WeakPolarHBondContact CE-O 3.35Å
363V98Very high98.2Very high5 Ų517.7 Ų17.73%0.038%0.082CC..Hα-helixtrans-57.4-31.7-176.8-65.40000113.3L126 L361 G367 I400 L403L126-V363 HydrophobicContact CD1-CB 4.03Å; L126-V363 HydrophobicContact CD1-CG2 4.3Å; L126-V363 HydrophobicContact CD2-CB 4.33Å; L126-V363 HydrophobicContact CD2-CG2 4Å; L361-V363 HydrophobicContact CD2-CG1 4.15Å; V363-G367 WeakPolarHBondContact O-CA 3.44Å; V363-G367 PolarHBondContact O-N 3.43Å; V363-I400 HydrophobicContact CG2-CG2 4.4Å; V363-L403 HydrophobicContact CG1-CD2 3.47Å; V363-L403 VanDerWaalsContact CG1-CD2 3.47Å
364N96.5Very high98.2Very high4 Ų417.6 Ų17.62%0.0218%0.082CC..Hα-helixtrans-71-28.5177.9-171.534000113.6P50 L126 K362 I366 R391P50-N364 HydrophobicContact CG-CB 4.31Å; P50-N364 PolarHBondContact O-ND2 2.9Å; L126-N364 HydrophobicContact CD2-CB 4Å; K362-N364 PolarHBondContact O-N 3.23Å; K362-N364 VanDerWaalsContact O-N 3.1Å; N364-I366 VanDerWaalsContact C-N 3.31Å; N364-I366 PolarHBondContact O-N 2.71Å; N364-R391 HydrophobicContact CB-CG 4.44Å; N364-R391 PolarHBondContact ND2-NH1 3.16Å
365Q96.5Very high98.2Very high2 Ų210.3 Ų10.31%0.0095%0.051CC..Hα-helixtrans-69.7-31.3-179.7-66.4-174-37.300112.5E59 A60 D337 C341 T342 K362E59-Q365 VanDerWaalsContact CD-CG 3.49Å; E59-Q365 HydrophobicContact CG-CB 4.12Å; E59-Q365 HydrophobicContact CG-CG 3.8Å; E59-Q365 PolarHBondContact OE1-NE2 3.07Å; A60-Q365 VanDerWaalsContact CB-O 3.23Å; A60-Q365 WeakPolarHBondContact CB-O 3.42Å; A60-Q365 PolarHBondContact N-O 3.07Å; D337-Q365 PolarHBondContact OD1-NE2 2.85Å; D337-Q365 PolarHBondContact OD1-OE1 3.29Å; C341-Q365 VanDerWaalsContact C-OE1 3.26Å; C341-Q365 WeakPolarHBondContact O-CB 3.47Å; T342-Q365 PolarHBondContact OG1-OE1 2.9Å; K362-Q365 HydrophobicContact CB-CB 4.28Å; K362-Q365 HydrophobicContact CB-CG 3.64Å; K362-Q365 HydrophobicContact CD-CG 4.14Å; K362-Q365 WeakPolarHBondContact O-CB 3.33Å; K362-Q365 PolarHBondContact O-N 3.47Å
366I97.2Very high98.1Very high8 Ų810.5 Ų10.54%0.0415%0.052CC..Hα-helixtrans-101.4-37179.2-165.256.6000112.7K117 T342 N343 N364 E371 S372K117-I366 WeakPolarHBondContact CD-O 3.47Å; K117-I366 WeakPolarHBondContact CE-O 3.38Å; K117-I366 PolarHBondContact NZ-O 3.07Å; T342-I366 HydrophobicContact CG2-CB 4.01Å; T342-I366 HydrophobicContact CG2-CG2 3.76Å; N343-I366 HydrophobicContact CB-CD1 4.39Å; N364-I366 VanDerWaalsContact C-N 3.31Å; N364-I366 PolarHBondContact O-N 2.71Å; I366-E371 HydrophobicContact CD1-CB 4.34Å; I366-E371 HydrophobicContact CG1-CB 3.42Å; I366-E371 VanDerWaalsContact CG1-CB 3.42Å; I366-E371 HydrophobicContact CG1-CG 4.29Å; I366-E371 HydrophobicContact CG2-CB 4.31Å; I366-S372 VanDerWaalsContact CG2-OG 3.24Å; I366-S372 WeakPolarHBondContact CG2-OG 3.35Å
367G97.2Very high98Very high0 Ų013.9 Ų13.90%07%0.068CC..  trans983.8168.100000116.9I125 L126 V363I125-G367 CarbonylContact C-O 3.58Å; I125-G367 WeakPolarHBondContact CG2-O 3.08Å; L126-G367 WeakPolarHBondContact CA-O 3.44Å; L126-G367 WeakPolarHBondContact CB-O 3.21Å; L126-G367 PolarHBondContact N-O 2.92Å; L126-G367 VanDerWaalsContact N-O 3.12Å; V363-G367 WeakPolarHBondContact O-CA 3.44Å; V363-G367 PolarHBondContact O-N 3.43Å
368S98.5Very high98Very high0 Ų015.5 Ų15.50%07%0.073CC..SBendtrans-151.6157.2171.1720000112.9E371 S372S368-E371 WeakPolarHBondContact CB-OE2 3.43Å; S368-E371 WeakPolarHBondContact OG-CB 3.27Å; S368-E371 VanDerWaalsContact OG-CG 3.24Å; S368-E371 WeakPolarHBondContact OG-CG 3.26Å; S368-E371 PolarHBondContact OG-N 2.97Å; S368-E371 VanDerWaalsContact OG-N 3.16Å; S368-E371 PolarHBondContact OG-OE2 3.43Å; S368-S372 WeakPolarHBondContact O-CB 3.29Å; S368-S372 PolarHBondContact O-N 3Å; S368-S372 PolarHBondContact O-OG 3.32Å
369V98.8Very high97.9Very high1 Ų115.5 Ų15.51%0.0067%0.073CC..Hα-helixtrans-64.6-43.9176.2176.70000110.6Q101 S129 L130 C133 S372 I373 F399Q101-V369 HydrophobicContact CG-CB 4.49Å; Q101-V369 HydrophobicContact CG-CG1 4.46Å; S129-V369 PolarHBondContact OG-N 3.39Å; L130-V369 HydrophobicContact CD2-CG2 3.77Å; C133-V369 HydrophobicContact CB-CG2 4.18Å; V369-S372 WeakPolarHBondContact O-CB 3.29Å; V369-S372 PolarHBondContact O-N 3.32Å; V369-I373 HydrophobicContact CG1-CD1 3.88Å; V369-I373 HydrophobicContact CG1-CG1 4.46Å; V369-I373 WeakPolarHBondContact O-CG1 3.39Å; V369-I373 PolarHBondContact O-N 2.99Å; V369-F399 HydrophobicContact CG1-CZ 4.33Å; V369-F399 HydrophobicContact CG2-CE1 4.21Å; V369-F399 HydrophobicContact CG2-CE2 4.37Å; V369-F399 HydrophobicContact CG2-CZ 3.61Å
370T98.6Very high97.8Very high16 Ų1619.4 Ų19.410%0.0989%0.088CC..Hα-helixtrans-61-48.3179.6-61.90000112A102 D105 S372 I373 Q374A102-T370 WeakPolarHBondContact CA-OG1 3.41Å; A102-T370 HydrophobicContact CB-CG2 4.04Å; D105-T370 WeakPolarHBondContact OD2-CB 3.1Å; D105-T370 PolarHBondContact OD2-N 2.98Å; D105-T370 PolarHBondContact OD2-OG1 3.23Å; T370-S372 VanDerWaalsContact C-N 3.3Å; T370-S372 PolarHBondContact O-N 2.83Å; T370-I373 PolarHBondContact O-N 3.14Å; T370-Q374 VanDerWaalsContact O-CG 3.31Å; T370-Q374 WeakPolarHBondContact O-CG 3.33Å; T370-Q374 PolarHBondContact O-N 3.21Å
371E98.2Very high97.6Very high30 Ų3026.5 Ų26.514%0.1412%0.121CC..Hα-helixtrans-67.6-32.8178.2-66.3167.3108.100111.7L109 K117 I366 S368 Q374 A375L109-E371 HydrophobicContact CD1-CG 4.16Å; K117-E371 WeakPolarHBondContact CE-OE2 3.47Å; K117-E371 VanDerWaalsContact NZ-CD 3.26Å; K117-E371 IonicContact NZ-OE1 3.73Å; K117-E371 PolarHBondContact NZ-OE1 2.79Å; K117-E371 IonicContact NZ-OE2 2.77Å; K117-E371 PolarHBondContact NZ-OE2 2.92Å; I366-E371 HydrophobicContact CD1-CB 4.34Å; I366-E371 HydrophobicContact CG1-CB 3.42Å; I366-E371 VanDerWaalsContact CG1-CB 3.42Å; I366-E371 HydrophobicContact CG1-CG 4.29Å; I366-E371 HydrophobicContact CG2-CB 4.31Å; S368-E371 WeakPolarHBondContact CB-OE2 3.43Å; S368-E371 WeakPolarHBondContact OG-CB 3.27Å; S368-E371 VanDerWaalsContact OG-CG 3.24Å; S368-E371 WeakPolarHBondContact OG-CG 3.26Å; S368-E371 PolarHBondContact OG-N 2.97Å; S368-E371 VanDerWaalsContact OG-N 3.16Å; S368-E371 PolarHBondContact OG-OE2 3.43Å; E371-Q374 PolarHBondContact O-N 2.98Å; E371-A375 WeakPolarHBondContact O-CB 3.39Å; E371-A375 PolarHBondContact O-N 2.96Å
372S98.6Very high97.5Very high0 Ų028.6 Ų28.60%014%0.136CC..Hα-helixtrans-63.2-43.5173.8-60.40000112I366 S368 V369 T370 Q374 A375 C376I366-S372 VanDerWaalsContact CG2-OG 3.24Å; I366-S372 WeakPolarHBondContact CG2-OG 3.35Å; S368-S372 WeakPolarHBondContact O-CB 3.29Å; S368-S372 PolarHBondContact O-N 3Å; S368-S372 PolarHBondContact O-OG 3.32Å; V369-S372 WeakPolarHBondContact O-CB 3.29Å; V369-S372 PolarHBondContact O-N 3.32Å; T370-S372 VanDerWaalsContact C-N 3.3Å; T370-S372 PolarHBondContact O-N 2.83Å; S372-Q374 VanDerWaalsContact C-N 3.35Å; S372-A375 PolarHBondContact O-N 2.9Å; S372-C376 PolarHBondContact O-N 3.3Å
373I98.5Very high97.4Very high9 Ų930.2 Ų30.25%0.04616%0.158CC..Hα-helixtrans-61.2-45.2174.3-69.4164.5000110.1L151 A152 V369 T370 A375 C376 Q377 L407L151-I373 HydrophobicContact CB-CD1 3.81Å; L151-I373 HydrophobicContact CD1-CD1 4.46Å; A152-I373 HydrophobicContact CB-CG2 3.93Å; V369-I373 HydrophobicContact CG1-CD1 3.88Å; V369-I373 HydrophobicContact CG1-CG1 4.46Å; V369-I373 WeakPolarHBondContact O-CG1 3.39Å; V369-I373 PolarHBondContact O-N 2.99Å; T370-I373 PolarHBondContact O-N 3.14Å; I373-A375 PolarHBondContact O-N 3.08Å; I373-C376 WeakPolarHBondContact O-CB 3.23Å; I373-C376 PolarHBondContact O-N 3.48Å; I373-Q377 HydrophobicContact CG2-CG 4.31Å; I373-Q377 WeakPolarHBondContact O-CB 3.4Å; I373-Q377 WeakPolarHBondContact O-CG 3.37Å; I373-Q377 PolarHBondContact O-N 2.65Å; I373-L407 HydrophobicContact CG1-CD2 3.96Å
374Q98Very high97.4Very high94 Ų9431 Ų3144%0.43916%0.16SC..Hα-helixtrans-61.8-42.5178.5-70.6169.5-0.500112.1T370 E371 S372 Q377 K378T370-Q374 VanDerWaalsContact O-CG 3.31Å; T370-Q374 WeakPolarHBondContact O-CG 3.33Å; T370-Q374 PolarHBondContact O-N 3.21Å; E371-Q374 PolarHBondContact O-N 2.98Å; S372-Q374 VanDerWaalsContact C-N 3.35Å; Q374-Q377 PolarHBondContact O-N 2.76Å; Q374-K378 WeakPolarHBondContact O-CB 3.37Å; Q374-K378 PolarHBondContact O-N 3Å
375A98.4Very high97.4Very high0 Ų031 Ų310%016%0.161CC..Hα-helixtrans-60.6-4717500000111.6T342 P344 I347 L359 E371 S372 I373 Q377 K378 A379T342-A375 HydrophobicContact CG2-CB 3.84Å; T342-A375 WeakPolarHBondContact O-CB 3.4Å; P344-A375 HydrophobicContact CG-CB 4.4Å; I347-A375 HydrophobicContact CD1-CB 3.72Å; L359-A375 HydrophobicContact CD2-CB 4.17Å; E371-A375 WeakPolarHBondContact O-CB 3.39Å; E371-A375 PolarHBondContact O-N 2.96Å; S372-A375 PolarHBondContact O-N 2.9Å; I373-A375 PolarHBondContact O-N 3.08Å; A375-Q377 PolarHBondContact O-N 3.36Å; A375-K378 PolarHBondContact O-N 3.41Å; A375-A379 PolarHBondContact O-N 3.33Å
376C98Very high97.5Very high3 Ų331 Ų312%0.0216%0.161CC..Hα-helixtrans-57.8-49.4174.5177.90000111.8L361 S372 I373 K378 A379 R380 L407L361-C376 HydrophobicContact CD1-CB 3.69Å; S372-C376 PolarHBondContact O-N 3.3Å; I373-C376 WeakPolarHBondContact O-CB 3.23Å; I373-C376 PolarHBondContact O-N 3.48Å; C376-K378 VanDerWaalsContact C-N 3.32Å; C376-K378 PolarHBondContact O-N 2.94Å; C376-A379 PolarHBondContact O-N 3.32Å; C376-R380 WeakPolarHBondContact O-CG 3.45Å; C376-R380 PolarHBondContact O-N 2.93Å; C376-L407 HydrophobicContact CB-CD1 4.02Å
377Q96.3Very high97.6Very high72 Ų7230.6 Ų30.634%0.33616%0.159SC..Hα-helixtrans-61.5-41.6-179.9-74173.3-16.600111.4A152 I373 Q374 A375 R380 Q381A152-Q377 PolarHBondContact O-NE2 3.06Å; I373-Q377 HydrophobicContact CG2-CG 4.31Å; I373-Q377 WeakPolarHBondContact O-CB 3.4Å; I373-Q377 WeakPolarHBondContact O-CG 3.37Å; I373-Q377 PolarHBondContact O-N 2.65Å; Q374-Q377 PolarHBondContact O-N 2.76Å; A375-Q377 PolarHBondContact O-N 3.36Å; Q377-R380 PolarHBondContact O-N 2.86Å; Q377-Q381 WeakPolarHBondContact O-CB 3.5Å; Q377-Q381 WeakPolarHBondContact O-CG 3.12Å; Q377-Q381 PolarHBondContact O-N 3.16Å
378K97.3Very high97.7Very high61 Ų6130.6 Ų30.627%0.26516%0.159SC..Hα-helixtrans-61.3-45.3177.8-173.865.4175.8-178.60112.5I347 I351 Q374 A375 C376 S382I347-K378 HydrophobicContact CG2-CB 4.44Å; I347-K378 HydrophobicContact CG2-CG 3.89Å; I351-K378 HydrophobicContact CD1-CG 4.42Å; Q374-K378 WeakPolarHBondContact O-CB 3.37Å; Q374-K378 PolarHBondContact O-N 3Å; A375-K378 PolarHBondContact O-N 3.41Å; C376-K378 VanDerWaalsContact C-N 3.32Å; C376-K378 PolarHBondContact O-N 2.94Å; K378-S382 PolarHBondContact O-N 3.27Å; K378-S382 PolarHBondContact O-OG 3.45Å
379A97.8Very high97.7Very high0 Ų030.8 Ų30.80%016%0.161CC..Hα-helixtrans-61.7-50.9175.800000110.9L359 A375 C376 Q381 S382 G383 W384 V386L359-A379 HydrophobicContact CB-CB 3.9Å; L359-A379 HydrophobicContact CD2-CB 3.98Å; A375-A379 PolarHBondContact O-N 3.33Å; C376-A379 PolarHBondContact O-N 3.32Å; A379-Q381 PolarHBondContact O-N 2.8Å; A379-S382 CarbonylContact O-C 3.52Å; A379-S382 WeakPolarHBondContact O-CA 3.43Å; A379-S382 WeakPolarHBondContact O-CB 3.34Å; A379-S382 PolarHBondContact O-N 2.91Å; A379-G383 PolarHBondContact O-N 2.85Å; A379-W384 HydrophobicContact CB-CB 4.09Å; A379-W384 HydrophobicContact CB-CE3 4.21Å; A379-W384 WeakPolarHBondContact O-CB 3.38Å; A379-W384 PolarHBondContact O-N 3.07Å; A379-W384 VanDerWaalsContact O-N 3.07Å; A379-V386 HydrophobicContact CB-CG2 3.83Å
380R95.4Very high97.6Very high83 Ų8330.9 Ų30.931%0.31316%0.161SC..Hα-helixtrans-62.7-38.7-179.6-69.9-173.973.5150.210.6113.3C376 Q377 S382 G383 V386 L407 A408C376-R380 WeakPolarHBondContact O-CG 3.45Å; C376-R380 PolarHBondContact O-N 2.93Å; Q377-R380 PolarHBondContact O-N 2.86Å; R380-S382 PolarHBondContact O-N 3.43Å; R380-G383 PolarHBondContact O-N 2.95Å; R380-V386 HydrophobicContact CG-CG2 4.03Å; R380-L407 PolarHBondContact NH1-O 3.42Å; R380-A408 PolarHBondContact NH1-O 2.7Å
381Q95.3Very high97.6Very high149 Ų14930.4 Ų30.470%0.69616%0.158SC*.Hα-helixtrans-59.7-24.6174.2-76.5167.311.700112.5Q377 A379Q377-Q381 WeakPolarHBondContact O-CB 3.5Å; Q377-Q381 WeakPolarHBondContact O-CG 3.12Å; Q377-Q381 PolarHBondContact O-N 3.16Å; A379-Q381 PolarHBondContact O-N 2.8Å
382S96.2Very high97.4Very high44 Ų4429.1 Ų29.131%0.30815%0.152SC..THydrogen-bonded Turntrans-96.210.8178.3-48.80000112.7I351 K378 A379 R380 W384I351-S382 WeakPolarHBondContact CD1-OG 3.23Å; K378-S382 PolarHBondContact O-N 3.27Å; K378-S382 PolarHBondContact O-OG 3.45Å; A379-S382 CarbonylContact O-C 3.52Å; A379-S382 WeakPolarHBondContact O-CA 3.43Å; A379-S382 WeakPolarHBondContact O-CB 3.34Å; A379-S382 PolarHBondContact O-N 2.91Å; R380-S382 PolarHBondContact O-N 3.43Å; S382-W384 VanDerWaalsContact C-N 3.29Å; S382-W384 PolarHBondContact O-N 3.22Å
383G95.8Very high97.4Very high53 Ų5329.1 Ų29.155%0.54615%0.152SC..THydrogen-bonded Turntrans74.614.1-179.700000114.5A379 R380A379-G383 PolarHBondContact O-N 2.85Å; R380-G383 PolarHBondContact O-N 2.95Å
384W97.6Very high97.3Very high21 Ų2128.9 Ų28.98%0.0815%0.151CC..  trans-82.8148.7179.4-67.88.6000112.2T340 I347 A350 I351 C356 N357 A379 S382T340-W384 HydrophobicContact CG2-CZ3 4.45Å; I347-W384 HydrophobicContact CG2-CZ3 4.19Å; A350-W384 HydrophobicContact CB-CH2 3.63Å; A350-W384 HydrophobicContact CB-CZ2 4.49Å; A350-W384 HydrophobicContact CB-CZ3 4.49Å; I351-W384 HydrophobicContact CB-CZ2 4.17Å; I351-W384 HydrophobicContact CG1-CD2 4.37Å; I351-W384 HydrophobicContact CG1-CH2 3.78Å; I351-W384 HydrophobicContact CG1-CZ2 3.44Å; I351-W384 VanDerWaalsContact CG1-CZ2 3.44Å; I351-W384 HydrophobicContact CG1-CZ3 4.37Å; C356-W384 VanDerWaalsContact O-CE2 3.28Å; C356-W384 WeakPolarHBondContact O-CZ2 3.26Å; C356-W384 PolarHBondContact O-NE1 2.87Å; C356-W384 WeakPolarHBondContact SG-CH2 3.42Å; C356-W384 WeakPolarHBondContact SG-CZ3 3.42Å; N357-W384 VanDerWaalsContact O-CA 3.25Å; N357-W384 WeakPolarHBondContact O-CA 3.45Å; N357-W384 WeakPolarHBondContact O-CB 3.24Å; A379-W384 HydrophobicContact CB-CB 4.09Å; A379-W384 HydrophobicContact CB-CE3 4.21Å; A379-W384 WeakPolarHBondContact O-CB 3.38Å; A379-W384 PolarHBondContact O-N 3.07Å; A379-W384 VanDerWaalsContact O-N 3.07Å; S382-W384 VanDerWaalsContact C-N 3.29Å; S382-W384 PolarHBondContact O-N 3.22Å
385G98.1Very high97.3Very high4 Ų424.7 Ų24.74%0.04113%0.131CC..EExtended strand (participates in β ladder)trans-68.1162.1161.700000111.2N357 C358 L359 R450N357-G385 PolarHBondContact O-N 2.91Å; N357-G385 VanDerWaalsContact O-N 3.08Å; C358-G385 VanDerWaalsContact CA-O 3.27Å; C358-G385 WeakPolarHBondContact CA-O 3.23Å; C358-G385 VanDerWaalsContact SG-C 3.55Å; C358-G385 PolarHBondContact SG-O 3.14Å; L359-G385 PolarHBondContact N-O 3.3Å; G385-R450 WeakPolarHBondContact CA-O 3.37Å
386V98.5Very high97.3Very high2 Ų230.7 Ų30.71%0.01216%0.159CC..EExtended strand (participates in β ladder)trans-134.8126.6172-177.80000108.3L359 L361 A379 R380 T409L359-V386 HydrophobicContact CB-CG2 4.37Å; L359-V386 HydrophobicContact CD2-CG1 4.36Å; L359-V386 HydrophobicContact CG-CG1 4.49Å; L359-V386 CarbonylContact O-C 3.54Å; L359-V386 WeakPolarHBondContact O-CA 3.38Å; L361-V386 HydrophobicContact CB-CG1 3.79Å; L361-V386 HydrophobicContact CD1-CG1 3.99Å; A379-V386 HydrophobicContact CB-CG2 3.83Å; R380-V386 HydrophobicContact CG-CG2 4.03Å; V386-T409 HydrophobicContact CB-CG2 3.84Å; V386-T409 HydrophobicContact CG1-CG2 3.81Å; V386-T409 WeakPolarHBondContact O-CB 3.49Å; V386-T409 PolarHBondContact O-OG1 3.17Å
387M98.8Very high97.3Very high0 Ų031.6 Ų31.60%016%0.164CC..EExtended strand (participates in β ladder)trans-111.5112.1174.2178.3-176.4-64.300108.6A163 M185 L359 L360 L361 Q411 K413A163-M387 HydrophobicContact CB-CE 4.45Å; A163-M387 HydrophobicContact CB-SD 4.48Å; M185-M387 HydrophobicContact CE-CE 4.38Å; L359-M387 PolarHBondContact O-N 3.24Å; L360-M387 CarbonylContact C-O 3.6Å; L360-M387 WeakPolarHBondContact CA-O 3.39Å; L360-M387 HydrophobicContact CD1-CB 4.03Å; L360-M387 HydrophobicContact CD1-CG 3.89Å; L360-M387 HydrophobicContact CD1-SD 3.73Å; L361-M387 PolarHBondContact N-O 3.26Å; M387-Q411 HydrophobicContact CB-CB 3.99Å; M387-Q411 HydrophobicContact CE-CB 4.37Å; M387-Q411 HydrophobicContact CG-CB 3.98Å; M387-K413 HydrophobicContact CG-CB 4.14Å; M387-K413 HydrophobicContact SD-CB 3.74Å; M387-K413 HydrophobicContact SD-CD 4.24Å
388V98.8Very high97.4Very high0 Ų029.7 Ų29.70%016%0.158CC..EExtended strand (participates in β ladder)trans-72.4133.2174.9173.40000108.5L361 I400 L403 V404 T409 Q411 I412 K413L361-V388 HydrophobicContact CD2-CG2 4.45Å; V388-I400 HydrophobicContact CG1-CB 3.86Å; V388-I400 HydrophobicContact CG1-CG2 4.39Å; V388-L403 HydrophobicContact CG1-CD2 4.16Å; V388-V404 HydrophobicContact CB-CB 3.87Å; V388-V404 HydrophobicContact CB-CG2 3.99Å; V388-V404 HydrophobicContact CG1-CB 4.25Å; V388-V404 HydrophobicContact CG2-CB 3.88Å; V388-V404 HydrophobicContact CG2-CG2 3.98Å; V388-T409 HydrophobicContact CG2-CG2 4.16Å; V388-Q411 PolarHBondContact N-O 2.66Å; V388-Q411 VanDerWaalsContact N-O 3.08Å; V388-I412 CarbonylContact O-C 3.56Å; V388-I412 VanDerWaalsContact O-CA 3.28Å; V388-I412 WeakPolarHBondContact O-CA 3.31Å; V388-K413 PolarHBondContact O-N 2.87Å
389S98.6Very high97.5Very high4 Ų427 Ų273%0.02815%0.146CC..EExtended strand (participates in β ladder)trans-133.8147.1-171.9-168.80000113.7L361 K413L361-S389 PolarHBondContact O-N 2.84Å; S389-K413 VanDerWaalsContact CA-O 3.31Å; S389-K413 WeakPolarHBondContact CA-O 3.33Å
390H97.7Very high97.5Very high3 Ų327.5 Ų27.51%0.01415%0.148CC..  trans-72.1-175.916868.9166.6000112.8N165 E224 K362 E394 I400 K413 T414 G415 R422N165-H390 PolarHBondContact ND2-NE2 2.87Å; N165-H390 VanDerWaalsContact ND2-NE2 3.16Å; E224-H390 IonicContact OE1-CE1 2.71Å; E224-H390 PolarHBondContact OE1-CE1 2.84Å; E224-H390 IonicContact OE1-NE2 2.83Å; E224-H390 PolarHBondContact OE1-NE2 3.5Å; K362-H390 VanDerWaalsContact CE-O 3.25Å; K362-H390 WeakPolarHBondContact CE-O 3.35Å; H390-E394 HydrophobicContact CB-CG 4.38Å; H390-E394 WeakPolarHBondContact CB-OE2 3.41Å; H390-I400 HydrophobicContact CB-CD1 3.93Å; H390-K413 PolarHBondContact CD2-O 2.92Å; H390-K413 PolarHBondContact N-O 2.94Å; H390-T414 WeakPolarHBondContact ND1-CA 3.29Å; H390-G415 VanDerWaalsContact CE1-CA 3.43Å; H390-G415 WeakPolarHBondContact CE1-CA 3.44Å; H390-G415 PolarHBondContact CE1-N 3.35Å; H390-G415 PolarHBondContact ND1-N 3.31Å; H390-R422 PolarHBondContact ND1-NH1 3.27Å
391R97Very high97.7Very high6 Ų623.6 Ų23.62%0.02313%0.134CC..  trans-117.5167.3161.1-53.7-64.9-64.1-104.315.9111.5P50 S51 G52 S54 E59 N364 E394 R422P50-R391 HydrophobicContact CB-CB 4.04Å; P50-R391 HydrophobicContact CB-CG 3.94Å; P50-R391 HydrophobicContact CG-CG 4.06Å; S51-R391 WeakPolarHBondContact O-CB 3.43Å; G52-R391 VanDerWaalsContact CA-NH2 3.35Å; S54-R391 PolarHBondContact O-NH2 2.96Å; E59-R391 IonicContact OE1-CZ 2.73Å; E59-R391 IonicContact OE1-NH1 3.65Å; E59-R391 IonicContact OE1-NH2 3.58Å; E59-R391 PolarHBondContact OE1-NH2 3Å; E59-R391 IonicContact OE2-CZ 3.2Å; E59-R391 IonicContact OE2-NH1 3.59Å; E59-R391 PolarHBondContact OE2-NH1 3.17Å; E59-R391 IonicContact OE2-NH2 2.79Å; E59-R391 PolarHBondContact OE2-NH2 3.34Å; N364-R391 HydrophobicContact CB-CG 4.44Å; N364-R391 PolarHBondContact ND2-NH1 3.16Å; R391-E394 PolarHBondContact N-OE2 3.25Å; R391-R422 PolarHBondContact O-NH1 3.04Å; R391-R422 PolarHBondContact O-NH2 3.33Å
392S95.7Very high97.9Very high3 Ų316.8 Ų16.82%0.02110%0.102CC..SBendtrans-66.4-3617652.60000113.2S28 A53 R422S28-S392 PolarHBondContact OG-O 3.46Å; A53-S392 WeakPolarHBondContact CB-OG 3.29Å; A53-S392 PolarHBondContact N-OG 3.37Å; S392-R422 PolarHBondContact O-NH2 3.2Å
393G96.8Very high98Very high0 Ų014.7 Ų14.70%09%0.087CC..BIsolated β-bridgetrans-90.794.1165.300000110.9D27 P50 S51D27-G393 VanDerWaalsContact OD2-CA 3.31Å; D27-G393 WeakPolarHBondContact OD2-CA 3.43Å; P50-G393 CarbonylContact C-O 3.54Å; P50-G393 VanDerWaalsContact CA-O 3.27Å; P50-G393 WeakPolarHBondContact CA-O 3.48Å; P50-G393 WeakPolarHBondContact CB-O 3.26Å; S51-G393 PolarHBondContact N-O 3.4Å; S51-G393 CarbonylContact O-C 3.49Å; S51-G393 WeakPolarHBondContact O-CA 3.35Å; S51-G393 PolarHBondContact O-N 3.29Å
394E97.5Very high98.2Very high5 Ų512.1 Ų12.12%0.0236%0.061CC..  trans-112.6165.4-172.3-166.548.3-109.500112D27 S28 P50 H390 R391 E421 R422 K425D27-E394 CarbonylContact C-O 3.53Å; D27-E394 WeakPolarHBondContact CA-O 2.98Å; S28-E394 WeakPolarHBondContact CB-O 3.47Å; S28-E394 PolarHBondContact N-O 3.05Å; S28-E394 PolarHBondContact OG-N 3.12Å; P50-E394 WeakPolarHBondContact CB-OE2 3.18Å; H390-E394 HydrophobicContact CB-CG 4.38Å; H390-E394 WeakPolarHBondContact CB-OE2 3.41Å; R391-E394 PolarHBondContact N-OE2 3.25Å; E394-E421 HydrophobicContact CB-CB 4.15Å; E394-E421 HydrophobicContact CG-CB 4.29Å; E394-R422 VanDerWaalsContact CG-NH1 3.34Å; E394-K425 VanDerWaalsContact CG-NZ 3.26Å; E394-K425 IonicContact OE1-NZ 2.91Å; E394-K425 PolarHBondContact OE1-NZ 3.07Å
395T98.2Very high98.2Very high5 Ų511.1 Ų11.13%0.0316%0.057CC..  trans-116.2-180176.671.80000110.1T33 A48 D397 E421 K425T33-T395 HydrophobicContact CG2-CG2 3.95Å; A48-T395 HydrophobicContact CB-CG2 3.87Å; T395-D397 PolarHBondContact O-N 3.39Å; T395-D397 VanDerWaalsContact OG1-CB 3.25Å; T395-D397 WeakPolarHBondContact OG1-CB 3.38Å; T395-D397 PolarHBondContact OG1-N 3.44Å; T395-D397 VanDerWaalsContact OG1-N 3.13Å; T395-E421 WeakPolarHBondContact O-CA 3.34Å; T395-E421 WeakPolarHBondContact O-CB 3.33Å; T395-K425 PolarHBondContact O-NZ 2.95Å
396E97.9Very high98.2Very high126 Ų12611 Ų1159%0.5896%0.056SC*.SBendtrans-79-0.8170.3-63.7-171.4155.500113T398 S420 E421 A424E396-T398 WeakPolarHBondContact O-CG2 3.49Å; E396-T398 PolarHBondContact O-N 3.07Å; E396-S420 VanDerWaalsContact OE1-CB 3.24Å; E396-S420 WeakPolarHBondContact OE1-CB 3.28Å; E396-E421 HydrophobicContact CG-CG 4.47Å; E396-A424 HydrophobicContact CB-CB 4.48Å; E396-A424 WeakPolarHBondContact O-CB 3.22Å
397D98.6Very high98.2Very high22 Ų2211 Ų1112%0.1186%0.055CC..  trans-61.9124.6177.8-162.8-43.8000110.9A47 A48 K134 T395 F399 K425A47-D397 WeakPolarHBondContact CA-OD2 3.41Å; A48-D397 HydrophobicContact CB-CB 4.23Å; A48-D397 PolarHBondContact N-OD2 3.02Å; K134-D397 IonicContact NZ-OD1 3.71Å; K134-D397 PolarHBondContact NZ-OD1 2.85Å; K134-D397 IonicContact NZ-OD2 3.36Å; K134-D397 PolarHBondContact NZ-OD2 3.19Å; T395-D397 PolarHBondContact O-N 3.39Å; T395-D397 VanDerWaalsContact OG1-CB 3.25Å; T395-D397 WeakPolarHBondContact OG1-CB 3.38Å; T395-D397 PolarHBondContact OG1-N 3.44Å; T395-D397 VanDerWaalsContact OG1-N 3.13Å; D397-F399 VanDerWaalsContact OD1-CB 3.32Å; D397-F399 WeakPolarHBondContact OD1-CB 3.48Å; D397-F399 PolarHBondContact OD1-N 3.49Å; D397-K425 WeakPolarHBondContact O-CE 3.34Å; D397-K425 PolarHBondContact O-NZ 3.4Å
398T98.6Very high98.2Very high33 Ų3311.2 Ų11.220%0.2026%0.057CC..  trans-926.9-174.763.50000113.5E396 I400 A401 A424 Q428E396-T398 WeakPolarHBondContact O-CG2 3.49Å; E396-T398 PolarHBondContact O-N 3.07Å; T398-I400 PolarHBondContact O-N 3.43Å; T398-A401 VanDerWaalsContact O-CB 3.24Å; T398-A401 WeakPolarHBondContact O-CB 3.28Å; T398-A401 PolarHBondContact O-N 3Å; T398-A424 HydrophobicContact CG2-CB 3.76Å; T398-A424 VanDerWaalsContact CG2-O 3.24Å; T398-A424 WeakPolarHBondContact CG2-O 3.43Å; T398-Q428 HydrophobicContact CG2-CB 3.98Å
399F98.9Very high98.1Very high5 Ų511.3 Ų11.32%0.0226%0.058CC..Hα-helixtrans-47.4-42.2-171.9-176.1-89.1000114.1L130 C133 L144 I148 V369 D397 A401 D402 L403L130-F399 HydrophobicContact CB-CD2 4.45Å; L130-F399 HydrophobicContact CD2-CD1 3.42Å; L130-F399 VanDerWaalsContact CD2-CD1 3.42Å; L130-F399 HydrophobicContact CD2-CD2 3.78Å; L130-F399 HydrophobicContact CD2-CE1 3.35Å; L130-F399 HydrophobicContact CD2-CE2 3.72Å; L130-F399 HydrophobicContact CD2-CG 3.64Å; L130-F399 HydrophobicContact CD2-CZ 3.52Å; C133-F399 HydrophobicContact CB-CE2 3.92Å; C133-F399 HydrophobicContact CB-CZ 4.33Å; L144-F399 HydrophobicContact CD1-CE2 4.42Å; L144-F399 HydrophobicContact CD2-CD2 3.95Å; L144-F399 HydrophobicContact CD2-CE2 4.3Å; I148-F399 HydrophobicContact CD1-CE1 4.47Å; I148-F399 HydrophobicContact CD1-CE2 4.18Å; I148-F399 HydrophobicContact CD1-CZ 3.93Å; V369-F399 HydrophobicContact CG1-CZ 4.33Å; V369-F399 HydrophobicContact CG2-CE1 4.21Å; V369-F399 HydrophobicContact CG2-CE2 4.37Å; V369-F399 HydrophobicContact CG2-CZ 3.61Å; D397-F399 VanDerWaalsContact OD1-CB 3.32Å; D397-F399 WeakPolarHBondContact OD1-CB 3.48Å; D397-F399 PolarHBondContact OD1-N 3.49Å; F399-A401 PolarHBondContact O-N 2.95Å; F399-D402 PolarHBondContact O-N 3.45Å; F399-D402 VanDerWaalsContact O-N 3.14Å; F399-L403 HydrophobicContact CD1-CB 4.22Å; F399-L403 HydrophobicContact CE1-CB 4.05Å; F399-L403 HydrophobicContact CE1-CD1 4Å; F399-L403 HydrophobicContact CE1-CD2 4.15Å; F399-L403 HydrophobicContact CE1-CG 4.3Å; F399-L403 WeakPolarHBondContact O-CB 3.45Å; F399-L403 PolarHBondContact O-N 3.12Å
400I98.7Very high98.1Very high10 Ų1011.1 Ų11.15%0.0516%0.057CC..Hα-helixtrans-66.8-23.5-177.666.5169.2000113.7V363 V388 H390 T398 L403 V404 I412 K425V363-I400 HydrophobicContact CG2-CG2 4.4Å; V388-I400 HydrophobicContact CG1-CB 3.86Å; V388-I400 HydrophobicContact CG1-CG2 4.39Å; H390-I400 HydrophobicContact CB-CD1 3.93Å; T398-I400 PolarHBondContact O-N 3.43Å; I400-L403 PolarHBondContact O-N 3.27Å; I400-V404 WeakPolarHBondContact O-CG1 3.43Å; I400-V404 PolarHBondContact O-N 2.94Å; I400-I412 HydrophobicContact CD1-CD1 4.5Å; I400-I412 HydrophobicContact CG1-CD1 4.43Å; I400-K425 HydrophobicContact CD1-CG 4.02Å; I400-K425 HydrophobicContact CG1-CG 3.62Å
401A98.9Very high98.1Very high0 Ų011 Ų110%06%0.056CC..Hα-helixtrans-68.2-39.3172.800000111.6T398 F399 V404 V405 K425 Q428 L429T398-A401 VanDerWaalsContact O-CB 3.24Å; T398-A401 WeakPolarHBondContact O-CB 3.28Å; T398-A401 PolarHBondContact O-N 3Å; F399-A401 PolarHBondContact O-N 2.95Å; A401-V404 VanDerWaalsContact O-CG1 3.27Å; A401-V404 WeakPolarHBondContact O-CG1 3.29Å; A401-V405 WeakPolarHBondContact O-CG2 3.48Å; A401-K425 HydrophobicContact CB-CB 4.22Å; A401-K425 WeakPolarHBondContact CB-O 3.45Å; A401-Q428 HydrophobicContact CB-CB 3.87Å; A401-Q428 HydrophobicContact CB-CG 3.78Å; A401-L429 HydrophobicContact CB-CD2 4.1Å; A401-L429 HydrophobicContact CB-CG 3.87Å; A401-L429 WeakPolarHBondContact O-CD2 3.22Å
402D98.9Very high98.2Very high6 Ų610.7 Ų10.73%0.0326%0.055CC..Hα-helixtrans-74.1-36.8172.6-72.6-93.3000111.5L144 Y145 I148 F399 V405 G406 Q428L144-D402 HydrophobicContact CB-CB 4.08Å; L144-D402 HydrophobicContact CD2-CB 3.77Å; L144-D402 HydrophobicContact CG-CB 3.75Å; Y145-D402 WeakPolarHBondContact CB-O 3.45Å; Y145-D402 PolarHBondContact N-OD1 3.4Å; I148-D402 HydrophobicContact CD1-CB 4.19Å; F399-D402 PolarHBondContact O-N 3.45Å; F399-D402 VanDerWaalsContact O-N 3.14Å; D402-V405 PolarHBondContact O-N 3.48Å; D402-G406 PolarHBondContact O-N 3.23Å; D402-Q428 PolarHBondContact OD2-NE2 3.37Å; D402-Q428 VanDerWaalsContact OD2-NE2 3.12Å
403L98.9Very high98.3Very high0 Ų010.6 Ų10.60%05%0.054CC..Hα-helixtrans-60-49.2178.5-174.768000112.1I148 L361 V363 V388 F399 I400 V405 G406 L407I148-L403 HydrophobicContact CD1-CB 4.33Å; I148-L403 HydrophobicContact CD1-CD1 4.29Å; I148-L403 HydrophobicContact CG2-CD1 3.9Å; L361-L403 HydrophobicContact CD2-CD2 3.79Å; V363-L403 HydrophobicContact CG1-CD2 3.47Å; V363-L403 VanDerWaalsContact CG1-CD2 3.47Å; V388-L403 HydrophobicContact CG1-CD2 4.16Å; F399-L403 HydrophobicContact CD1-CB 4.22Å; F399-L403 HydrophobicContact CE1-CB 4.05Å; F399-L403 HydrophobicContact CE1-CD1 4Å; F399-L403 HydrophobicContact CE1-CD2 4.15Å; F399-L403 HydrophobicContact CE1-CG 4.3Å; F399-L403 WeakPolarHBondContact O-CB 3.45Å; F399-L403 PolarHBondContact O-N 3.12Å; I400-L403 PolarHBondContact O-N 3.27Å; L403-V405 VanDerWaalsContact C-N 3.3Å; L403-V405 PolarHBondContact O-N 3.23Å; L403-G406 PolarHBondContact O-N 3.43Å; L403-L407 HydrophobicContact CD1-CD1 3.7Å; L403-L407 HydrophobicContact CD1-CG 3.9Å; L403-L407 HydrophobicContact CD2-CD1 4.46Å; L403-L407 HydrophobicContact CG-CD1 3.79Å; L403-L407 HydrophobicContact CG-CG 4.22Å; L403-L407 VanDerWaalsContact O-CB 3.28Å; L403-L407 WeakPolarHBondContact O-CB 3.49Å; L403-L407 VanDerWaalsContact O-CG 3.3Å; L403-L407 WeakPolarHBondContact O-CG 3.47Å; L403-L407 PolarHBondContact O-N 2.75Å
404V98.8Very high98.4Very high0 Ų010.6 Ų10.60%05%0.054CC..Hα-helixtrans-62.2-38.3-177.867.80000112.3P160 V388 I400 A401 A408 T409 Q411 I412 L429P160-V404 HydrophobicContact CB-CG1 4.27Å; P160-V404 HydrophobicContact CB-CG2 3.62Å; P160-V404 HydrophobicContact CG-CG1 3.72Å; P160-V404 HydrophobicContact CG-CG2 4.03Å; V388-V404 HydrophobicContact CB-CB 3.87Å; V388-V404 HydrophobicContact CB-CG2 3.99Å; V388-V404 HydrophobicContact CG1-CB 4.25Å; V388-V404 HydrophobicContact CG2-CB 3.88Å; V388-V404 HydrophobicContact CG2-CG2 3.98Å; I400-V404 WeakPolarHBondContact O-CG1 3.43Å; I400-V404 PolarHBondContact O-N 2.94Å; A401-V404 VanDerWaalsContact O-CG1 3.27Å; A401-V404 WeakPolarHBondContact O-CG1 3.29Å; V404-A408 PolarHBondContact O-N 2.93Å; V404-A408 VanDerWaalsContact O-N 3.12Å; V404-T409 WeakPolarHBondContact CG2-OG1 3.31Å; V404-T409 PolarHBondContact O-N 2.91Å; V404-Q411 WeakPolarHBondContact CG2-O 3.48Å; V404-I412 HydrophobicContact CB-CB 4.45Å; V404-I412 HydrophobicContact CG1-CB 4.28Å; V404-I412 HydrophobicContact CG1-CD1 3.99Å; V404-I412 HydrophobicContact CG2-CB 4.08Å; V404-L429 HydrophobicContact CG1-CD2 3.99Å
405V98.6Very high98.4Very high0 Ų010.4 Ų10.40%05%0.053CC..Hα-helixtrans-72.3-45.9177.6176.90000110.4Y145 V157 L159 A401 D402 L403 L407 A408 L429 I432 L436Y145-V405 HydrophobicContact CD2-CG1 3.64Å; Y145-V405 HydrophobicContact CE2-CG1 4.35Å; Y145-V405 HydrophobicContact CG-CB 4.48Å; Y145-V405 HydrophobicContact CG-CG1 4.02Å; V157-V405 HydrophobicContact CB-CG1 3.79Å; V157-V405 WeakPolarHBondContact CB-O 3.5Å; V157-V405 HydrophobicContact CG1-CG1 4.41Å; V157-V405 HydrophobicContact CG2-CG1 4.16Å; L159-V405 HydrophobicContact CD2-CG2 4.3Å; A401-V405 WeakPolarHBondContact O-CG2 3.48Å; D402-V405 PolarHBondContact O-N 3.48Å; L403-V405 VanDerWaalsContact C-N 3.3Å; L403-V405 PolarHBondContact O-N 3.23Å; V405-L407 PolarHBondContact O-N 2.87Å; V405-A408 WeakPolarHBondContact O-CA 3.44Å; V405-A408 PolarHBondContact O-N 2.91Å; V405-L429 HydrophobicContact CG2-CD2 3.61Å; V405-I432 HydrophobicContact CB-CG2 4.48Å; V405-I432 HydrophobicContact CG1-CG2 3.99Å; V405-I432 HydrophobicContact CG2-CD1 4.36Å; V405-I432 HydrophobicContact CG2-CG2 4.15Å; V405-L436 HydrophobicContact CG1-CD1 4.48Å
406G98.4Very high98.4Very high0 Ų010.1 Ų10.10%05%0.052CC..Hα-helixtrans-64.6-39.3-179.600000113.4Y145 A149 V154 D402 L403 A408Y145-G406 WeakPolarHBondContact O-CA 3.45Å; A149-G406 VanDerWaalsContact CA-O 3.25Å; A149-G406 WeakPolarHBondContact CA-O 3.33Å; A149-G406 WeakPolarHBondContact CB-O 3.46Å; V154-G406 WeakPolarHBondContact CB-O 3.3Å; D402-G406 PolarHBondContact O-N 3.23Å; L403-G406 PolarHBondContact O-N 3.43Å; G406-A408 PolarHBondContact O-N 3.39Å
407L98.3Very high98.4Very high2 Ų24.8 Ų4.81%0.013%0.028CC..THydrogen-bonded Turntrans-77.1-11173.2-67.5-175.6000113.3I148 A152 L361 I373 C376 R380 L403 V405 T409I148-L407 HydrophobicContact CG2-CD2 4.27Å; I148-L407 HydrophobicContact CG2-CG 4.26Å; A152-L407 HydrophobicContact CB-CD2 3.61Å; L361-L407 HydrophobicContact CD1-CD1 3.88Å; I373-L407 HydrophobicContact CG1-CD2 3.96Å; C376-L407 HydrophobicContact CB-CD1 4.02Å; R380-L407 PolarHBondContact NH1-O 3.42Å; L403-L407 HydrophobicContact CD1-CD1 3.7Å; L403-L407 HydrophobicContact CD1-CG 3.9Å; L403-L407 HydrophobicContact CD2-CD1 4.46Å; L403-L407 HydrophobicContact CG-CD1 3.79Å; L403-L407 HydrophobicContact CG-CG 4.22Å; L403-L407 VanDerWaalsContact O-CB 3.28Å; L403-L407 WeakPolarHBondContact O-CB 3.49Å; L403-L407 VanDerWaalsContact O-CG 3.3Å; L403-L407 WeakPolarHBondContact O-CG 3.47Å; L403-L407 PolarHBondContact O-N 2.75Å; V405-L407 PolarHBondContact O-N 2.87Å; L407-T409 VanDerWaalsContact C-N 3.28Å; L407-T409 HydrophobicContact CB-CG2 3.51Å; L407-T409 HydrophobicContact CD1-CG2 4.25Å; L407-T409 PolarHBondContact O-N 3.09Å
408A97.7Very high98.4Very high5 Ų54.9 Ų4.94%0.0413%0.03CC..THydrogen-bonded Turntrans46.249.6-174.600000112.6V154 I158 R380 V404 V405 G406 P452V154-A408 HydrophobicContact CG1-CB 3.72Å; I158-A408 HydrophobicContact CG2-CB 3.93Å; R380-A408 PolarHBondContact NH1-O 2.7Å; V404-A408 PolarHBondContact O-N 2.93Å; V404-A408 VanDerWaalsContact O-N 3.12Å; V405-A408 WeakPolarHBondContact O-CA 3.44Å; V405-A408 PolarHBondContact O-N 2.91Å; G406-A408 PolarHBondContact O-N 3.39Å; A408-P452 VanDerWaalsContact O-CG 3.29Å; A408-P452 WeakPolarHBondContact O-CG 3.34Å
409T98Very high98.3Very high3 Ų310.1 Ų10.12%0.0185%0.046CC..  trans-82.8-20.6-17668.90000113V386 V388 V404 L407 Q411V386-T409 HydrophobicContact CB-CG2 3.84Å; V386-T409 HydrophobicContact CG1-CG2 3.81Å; V386-T409 WeakPolarHBondContact O-CB 3.49Å; V386-T409 PolarHBondContact O-OG1 3.17Å; V388-T409 HydrophobicContact CG2-CG2 4.16Å; V404-T409 WeakPolarHBondContact CG2-OG1 3.31Å; V404-T409 PolarHBondContact O-N 2.91Å; L407-T409 VanDerWaalsContact C-N 3.28Å; L407-T409 HydrophobicContact CB-CG2 3.51Å; L407-T409 HydrophobicContact CD1-CG2 4.25Å; L407-T409 PolarHBondContact O-N 3.09Å; T409-Q411 VanDerWaalsContact C-N 3.33Å; T409-Q411 PolarHBondContact O-N 2.93Å; T409-Q411 PolarHBondContact OG1-O 3.1Å
410G98Very high98.2Very high0 Ų013 Ų130%07%0.067CC..EExtended strand (participates in β ladder)trans84.3-3.1172.700000115.4P160 V161 A445P160-G410 CarbonylContact C-O 3.47Å; P160-G410 WeakPolarHBondContact CA-O 3.29Å; V161-G410 PolarHBondContact N-O 2.76Å; G410-A445 WeakPolarHBondContact O-CB 3.4Å
411Q98.4Very high98.2Very high0 Ų014.7 Ų14.70%08%0.075CC..EExtended strand (participates in β ladder)trans-144.6136-177.7-64.6173.273.400111.7V161 M387 V388 V404 T409 F449V161-Q411 WeakPolarHBondContact O-CA 3.42Å; M387-Q411 HydrophobicContact CB-CB 3.99Å; M387-Q411 HydrophobicContact CE-CB 4.37Å; M387-Q411 HydrophobicContact CG-CB 3.98Å; V388-Q411 PolarHBondContact N-O 2.66Å; V388-Q411 VanDerWaalsContact N-O 3.08Å; V404-Q411 WeakPolarHBondContact CG2-O 3.48Å; T409-Q411 VanDerWaalsContact C-N 3.33Å; T409-Q411 PolarHBondContact O-N 2.93Å; T409-Q411 PolarHBondContact OG1-O 3.1Å; Q411-F449 HydrophobicContact CG-CB 3.8Å; Q411-F449 HydrophobicContact CG-CD2 3.73Å; Q411-F449 HydrophobicContact CG-CG 4.28Å; Q411-F449 WeakPolarHBondContact CG-O 3.38Å; Q411-F449 PolarHBondContact NE2-O 2.76Å; Q411-F449 VanDerWaalsContact OE1-CD2 3.29Å
412I98.8Very high98.1Very high0 Ų014.8 Ų14.80%08%0.075CC..EExtended strand (participates in β ladder)trans-132.6135.8173.2-169.6173.3000111.3P160 V161 P162 A163 V388 I400 V404 T414 L429P160-I412 HydrophobicContact CB-CB 4.11Å; P160-I412 HydrophobicContact CB-CG2 3.88Å; P160-I412 HydrophobicContact CG-CB 4.06Å; P160-I412 HydrophobicContact CG-CG2 3.55Å; V161-I412 PolarHBondContact O-N 3Å; P162-I412 CarbonylContact C-O 3.6Å; P162-I412 WeakPolarHBondContact CA-O 2.96Å; P162-I412 HydrophobicContact CB-CG2 4.33Å; A163-I412 PolarHBondContact N-O 2.79Å; V388-I412 CarbonylContact O-C 3.56Å; V388-I412 VanDerWaalsContact O-CA 3.28Å; V388-I412 WeakPolarHBondContact O-CA 3.31Å; I400-I412 HydrophobicContact CD1-CD1 4.5Å; I400-I412 HydrophobicContact CG1-CD1 4.43Å; V404-I412 HydrophobicContact CB-CB 4.45Å; V404-I412 HydrophobicContact CG1-CB 4.28Å; V404-I412 HydrophobicContact CG1-CD1 3.99Å; V404-I412 HydrophobicContact CG2-CB 4.08Å; I412-T414 HydrophobicContact CD1-CG2 4.14Å; I412-T414 HydrophobicContact CG1-CG2 4.34Å; I412-L429 HydrophobicContact CD1-CD1 4.07Å; I412-L429 HydrophobicContact CG2-CD1 3.95Å
413K98.6Very high98.1Very high1 Ų117 Ų170%0.0049%0.086CC..EExtended strand (participates in β ladder)trans-113111.1170.8176.1179.4170.8176.70108.6A163 N165 E181 M183 D259 E312 L360 M387 V388 S389 H390A163-K413 HydrophobicContact CB-CB 4.31Å; N165-K413 WeakPolarHBondContact ND2-CE 3.24Å; E181-K413 IonicContact OE1-NZ 3.89Å; E181-K413 WeakPolarHBondContact OE2-CE 3.15Å; E181-K413 IonicContact OE2-NZ 2.85Å; E181-K413 PolarHBondContact OE2-NZ 3.08Å; M183-K413 HydrophobicContact CE-CD 4.49Å; M183-K413 HydrophobicContact SD-CD 3.9Å; M183-K413 HydrophobicContact SD-CG 4.12Å; D259-K413 IonicContact OD2-NZ 3.43Å; D259-K413 PolarHBondContact OD2-NZ 3.25Å; E312-K413 IonicContact OE1-NZ 3.52Å; E312-K413 PolarHBondContact OE1-NZ 3.04Å; E312-K413 IonicContact OE2-NZ 3.59Å; E312-K413 PolarHBondContact OE2-NZ 3.29Å; L360-K413 HydrophobicContact CD1-CD 4.25Å; M387-K413 HydrophobicContact CG-CB 4.14Å; M387-K413 HydrophobicContact SD-CB 3.74Å; M387-K413 HydrophobicContact SD-CD 4.24Å; V388-K413 PolarHBondContact O-N 2.87Å; S389-K413 VanDerWaalsContact CA-O 3.31Å; S389-K413 WeakPolarHBondContact CA-O 3.33Å; H390-K413 PolarHBondContact CD2-O 2.92Å; H390-K413 PolarHBondContact N-O 2.94Å
414T97.8Very high98.1Very high0 Ų017.9 Ų17.90%09%0.094CC..  trans-141.730.4-178.5-171.30000113.9H390 I412 R422 K425 Y426H390-T414 WeakPolarHBondContact ND1-CA 3.29Å; I412-T414 HydrophobicContact CD1-CG2 4.14Å; I412-T414 HydrophobicContact CG1-CG2 4.34Å; T414-R422 WeakPolarHBondContact O-CB 3.43Å; T414-R422 VanDerWaalsContact O-CD 3.25Å; T414-R422 WeakPolarHBondContact O-CD 3.49Å; T414-K425 HydrophobicContact CG2-CB 3.94Å; T414-Y426 HydrophobicContact CG2-CD1 3.72Å; T414-Y426 HydrophobicContact CG2-CD2 4.11Å; T414-Y426 HydrophobicContact CG2-CE1 3.24Å; T414-Y426 HydrophobicContact CG2-CE2 3.66Å; T414-Y426 HydrophobicContact CG2-CG 4.15Å; T414-Y426 WeakPolarHBondContact CG2-OH 3.31Å
415G98Very high98.1Very high0 Ų017.9 Ų17.90%09%0.094CC..  trans93.2-168.9171.300000114.6F164 N165 H390 Y426F164-G415 WeakPolarHBondContact CA-O 3.49Å; N165-G415 PolarHBondContact N-O 3.17Å; N165-G415 VanDerWaalsContact N-O 3.16Å; H390-G415 VanDerWaalsContact CE1-CA 3.43Å; H390-G415 WeakPolarHBondContact CE1-CA 3.44Å; H390-G415 PolarHBondContact CE1-N 3.35Å; H390-G415 PolarHBondContact ND1-N 3.31Å; G415-Y426 PolarHBondContact O-OH 3.34Å
416A98.3Very high98.1Very high0 Ų017.9 Ų17.90%09%0.094CC..SBendtrans-65.2160.6171.700000111.2N165 Y203 E224 G225 C418N165-A416 WeakPolarHBondContact O-CA 3.41Å; N165-A416 WeakPolarHBondContact O-CB 3.31Å; N165-A416 PolarHBondContact O-N 3.25Å; Y203-A416 HydrophobicContact CD2-CB 4.39Å; Y203-A416 HydrophobicContact CE2-CB 3.9Å; E224-A416 PolarHBondContact O-N 3.42Å; G225-A416 VanDerWaalsContact O-CB 3.27Å; G225-A416 WeakPolarHBondContact O-CB 3.29Å; A416-C418 PolarHBondContact O-N 3.13Å
417P98.1Very high98.1Very high14 Ų1421 Ų219%0.09111%0.11CC..SBendtrans-73.347.9169.833.2-36.2000111.8F164 M196 Y203F164-P417 HydrophobicContact CD1-CB 4.16Å; F164-P417 HydrophobicContact CD1-CG 4.3Å; F164-P417 HydrophobicContact CE1-CB 4.13Å; M196-P417 HydrophobicContact CE-CB 4.4Å; Y203-P417 HydrophobicContact CD1-CG 4.01Å; Y203-P417 HydrophobicContact CD2-CG 4.48Å; Y203-P417 HydrophobicContact CG-CG 3.83Å
418C97.5Very high98.2Very high23 Ų2322.6 Ų22.616%0.15512%0.118CC..  trans-154.3168175.976.60000110.6Y203 G225 A416 R422Y203-C418 HydrophobicContact CE1-CB 4.19Å; Y203-C418 PolarHBondContact OH-SG 3.31Å; G225-C418 PolarHBondContact O-SG 2.99Å; A416-C418 PolarHBondContact O-N 3.13Å; C418-R422 WeakPolarHBondContact O-CB 3.41Å; C418-R422 WeakPolarHBondContact O-CG 3.45Å
419R97Very high98.2Very high143 Ų14322.3 Ų22.354%0.5412%0.116SC..SBendtrans70.8132.5-172.7-47.4-60.7-177.3175.92.1113E421 R422 L423R419-E421 VanDerWaalsContact C-N 3.29Å; R419-E421 WeakPolarHBondContact CB-OE2 3.36Å; R419-E421 PolarHBondContact O-N 3.31Å; R419-R422 HydrophobicContact CB-CG 4.13Å; R419-R422 WeakPolarHBondContact O-CB 3.5Å; R419-R422 PolarHBondContact O-N 3.41Å; R419-R422 VanDerWaalsContact O-N 3.11Å; R419-L423 WeakPolarHBondContact O-CB 3.46Å; R419-L423 WeakPolarHBondContact O-CG 3.01Å; R419-L423 PolarHBondContact O-N 2.88Å
420S97.2Very high98.3Very high65 Ų6524.7 Ų24.746%0.45513%0.128SC..Hα-helixtrans-63.5-34.5-167.4-62.10000112.9E396 R422 L423 A424E396-S420 VanDerWaalsContact OE1-CB 3.24Å; E396-S420 WeakPolarHBondContact OE1-CB 3.28Å; S420-R422 PolarHBondContact O-N 3.29Å; S420-L423 PolarHBondContact O-N 3.4Å; S420-A424 WeakPolarHBondContact O-CB 3.37Å; S420-A424 PolarHBondContact O-N 2.98Å
421E97.8Very high98.3Very high47 Ų4731.3 Ų31.322%0.2215%0.153CC..Hα-helixtrans-66.1-26.8-179.8-49.891.7154.100111.7S28 E394 T395 E396 R419 K425S28-E421 WeakPolarHBondContact CA-OE1 3.21Å; S28-E421 WeakPolarHBondContact CB-OE1 3.27Å; E394-E421 HydrophobicContact CB-CB 4.15Å; E394-E421 HydrophobicContact CG-CB 4.29Å; T395-E421 WeakPolarHBondContact O-CA 3.34Å; T395-E421 WeakPolarHBondContact O-CB 3.33Å; E396-E421 HydrophobicContact CG-CG 4.47Å; R419-E421 VanDerWaalsContact C-N 3.29Å; R419-E421 WeakPolarHBondContact CB-OE2 3.36Å; R419-E421 PolarHBondContact O-N 3.31Å; E421-K425 WeakPolarHBondContact O-CD 3.42Å; E421-K425 WeakPolarHBondContact O-CE 3.38Å; E421-K425 PolarHBondContact O-NZ 2.77Å
422R98.2Very high98.3Very high2 Ų231.4 Ų31.41%0.00815%0.153CC..Hα-helixtrans-88.8-53.4174.6-46.8-52.6172.7-172.64.7110.6D223 H390 R391 S392 E394 T414 C418 R419 S420 A424 K425 Y426D223-R422 PolarHBondContact O-NH2 3.45Å; H390-R422 PolarHBondContact ND1-NH1 3.27Å; R391-R422 PolarHBondContact O-NH1 3.04Å; R391-R422 PolarHBondContact O-NH2 3.33Å; S392-R422 PolarHBondContact O-NH2 3.2Å; E394-R422 VanDerWaalsContact CG-NH1 3.34Å; T414-R422 WeakPolarHBondContact O-CB 3.43Å; T414-R422 VanDerWaalsContact O-CD 3.25Å; T414-R422 WeakPolarHBondContact O-CD 3.49Å; C418-R422 WeakPolarHBondContact O-CB 3.41Å; C418-R422 WeakPolarHBondContact O-CG 3.45Å; R419-R422 HydrophobicContact CB-CG 4.13Å; R419-R422 WeakPolarHBondContact O-CB 3.5Å; R419-R422 PolarHBondContact O-N 3.41Å; R419-R422 VanDerWaalsContact O-N 3.11Å; S420-R422 PolarHBondContact O-N 3.29Å; R422-A424 PolarHBondContact O-N 3.23Å; R422-K425 PolarHBondContact O-N 2.62Å; R422-K425 VanDerWaalsContact O-N 3.09Å; R422-Y426 PolarHBondContact O-N 3.11Å
423L98.4Very high98.3Very high51 Ų5131.7 Ų31.727%0.26716%0.155SC..Hα-helixtrans-60-31.3-178.3-75.7174.3000112.7R419 S420 K425 Y426 N427R419-L423 WeakPolarHBondContact O-CB 3.46Å; R419-L423 WeakPolarHBondContact O-CG 3.01Å; R419-L423 PolarHBondContact O-N 2.88Å; S420-L423 PolarHBondContact O-N 3.4Å; L423-K425 PolarHBondContact O-N 2.6Å; L423-Y426 PolarHBondContact O-N 3.1Å; L423-N427 VanDerWaalsContact O-CB 3.26Å; L423-N427 WeakPolarHBondContact O-CB 3.48Å; L423-N427 VanDerWaalsContact O-CG 3.25Å; L423-N427 PolarHBondContact O-N 2.91Å; L423-N427 PolarHBondContact O-ND2 2.96Å
424A98.6Very high98.3Very high19 Ų1936.9 Ų36.916%0.15718%0.179CC..Hα-helixtrans-56-41.8176.300000111.3E396 T398 S420 R422 Q428E396-A424 HydrophobicContact CB-CB 4.48Å; E396-A424 WeakPolarHBondContact O-CB 3.22Å; T398-A424 HydrophobicContact CG2-CB 3.76Å; T398-A424 VanDerWaalsContact CG2-O 3.24Å; T398-A424 WeakPolarHBondContact CG2-O 3.43Å; S420-A424 WeakPolarHBondContact O-CB 3.37Å; S420-A424 PolarHBondContact O-N 2.98Å; R422-A424 PolarHBondContact O-N 3.23Å; A424-Q428 WeakPolarHBondContact O-CB 3.48Å; A424-Q428 PolarHBondContact O-N 3.39Å
425K98.7Very high98.3Very high0 Ų039.4 Ų39.40%019%0.191CC..Hα-helixtrans-68.7-47.4176.9-7369.2158.3165.60111.5E394 T395 D397 I400 A401 T414 E421 R422 L423 N427 Q428 L429E394-K425 VanDerWaalsContact CG-NZ 3.26Å; E394-K425 IonicContact OE1-NZ 2.91Å; E394-K425 PolarHBondContact OE1-NZ 3.07Å; T395-K425 PolarHBondContact O-NZ 2.95Å; D397-K425 WeakPolarHBondContact O-CE 3.34Å; D397-K425 PolarHBondContact O-NZ 3.4Å; I400-K425 HydrophobicContact CD1-CG 4.02Å; I400-K425 HydrophobicContact CG1-CG 3.62Å; A401-K425 HydrophobicContact CB-CB 4.22Å; A401-K425 WeakPolarHBondContact CB-O 3.45Å; T414-K425 HydrophobicContact CG2-CB 3.94Å; E421-K425 WeakPolarHBondContact O-CD 3.42Å; E421-K425 WeakPolarHBondContact O-CE 3.38Å; E421-K425 PolarHBondContact O-NZ 2.77Å; R422-K425 PolarHBondContact O-N 2.62Å; R422-K425 VanDerWaalsContact O-N 3.09Å; L423-K425 PolarHBondContact O-N 2.6Å; K425-N427 PolarHBondContact O-N 3.34Å; K425-Q428 WeakPolarHBondContact O-CB 3.45Å; K425-Q428 PolarHBondContact O-N 3.44Å; K425-L429 PolarHBondContact O-N 3Å
426Y98.8Very high98.3Very high0 Ų039.5 Ų39.50%019%0.191CC..Hα-helixtrans-61.4-43.2178.2-69.3-48.2000112.5P162 F164 F192 M196 T414 G415 R422 L423 Q428 L429 L430P162-Y426 HydrophobicContact CB-CD1 4.46Å; P162-Y426 HydrophobicContact CB-CE1 3.66Å; F164-Y426 HydrophobicContact CD1-CE1 4.14Å; F164-Y426 AromaticContact CD1-CE2 3.89Å; F164-Y426 HydrophobicContact CD1-CE2 3.89Å; F164-Y426 AromaticContact CD1-CZ 3.48Å; F164-Y426 VanDerWaalsContact CD1-CZ 3.48Å; F164-Y426 VanDerWaalsContact CD1-OH 3.23Å; F164-Y426 WeakPolarHBondContact CD1-OH 3.48Å; F164-Y426 HydrophobicContact CE1-CD1 4.22Å; F164-Y426 HydrophobicContact CE1-CD2 4.36Å; F164-Y426 AromaticContact CE1-CE1 3.64Å; F164-Y426 HydrophobicContact CE1-CE1 3.64Å; F164-Y426 AromaticContact CE1-CE2 3.8Å; F164-Y426 HydrophobicContact CE1-CE2 3.8Å; F164-Y426 AromaticContact CE1-CZ 3.4Å; F164-Y426 VanDerWaalsContact CE1-CZ 3.4Å; F164-Y426 HydrophobicContact CZ-CE1 4.46Å; F192-Y426 HydrophobicContact CZ-CD1 4.06Å; M196-Y426 HydrophobicContact CE-CD1 4.35Å; M196-Y426 HydrophobicContact CE-CD2 4.17Å; M196-Y426 HydrophobicContact CE-CG 3.84Å; M196-Y426 HydrophobicContact SD-CD1 3.55Å; M196-Y426 VanDerWaalsContact SD-CD1 3.55Å; M196-Y426 HydrophobicContact SD-CD2 4.38Å; M196-Y426 HydrophobicContact SD-CE1 4.21Å; M196-Y426 HydrophobicContact SD-CG 3.65Å; T414-Y426 HydrophobicContact CG2-CD1 3.72Å; T414-Y426 HydrophobicContact CG2-CD2 4.11Å; T414-Y426 HydrophobicContact CG2-CE1 3.24Å; T414-Y426 HydrophobicContact CG2-CE2 3.66Å; T414-Y426 HydrophobicContact CG2-CG 4.15Å; T414-Y426 WeakPolarHBondContact CG2-OH 3.31Å; G415-Y426 PolarHBondContact O-OH 3.34Å; R422-Y426 PolarHBondContact O-N 3.11Å; L423-Y426 PolarHBondContact O-N 3.1Å; Y426-Q428 VanDerWaalsContact C-N 3.31Å; Y426-Q428 PolarHBondContact O-N 2.97Å; Y426-L429 WeakPolarHBondContact O-CB 3.32Å; Y426-L429 PolarHBondContact O-N 2.89Å; Y426-L430 PolarHBondContact O-N 2.96Å
427N98.8Very high98.3Very high66 Ų6644.6 Ų44.635%0.35322%0.215SC..Hα-helixtrans-66.8-34.2176-71-29.9000111.9L423 K425 L429 L430 R431L423-N427 VanDerWaalsContact O-CB 3.26Å; L423-N427 WeakPolarHBondContact O-CB 3.48Å; L423-N427 VanDerWaalsContact O-CG 3.25Å; L423-N427 PolarHBondContact O-N 2.91Å; L423-N427 PolarHBondContact O-ND2 2.96Å; K425-N427 PolarHBondContact O-N 3.34Å; N427-L429 VanDerWaalsContact C-N 3.34Å; N427-L430 PolarHBondContact O-N 2.72Å; N427-R431 WeakPolarHBondContact O-CG 3.5Å; N427-R431 PolarHBondContact O-N 2.97Å; N427-R431 VanDerWaalsContact O-N 3.14Å
428Q98.8Very high98.3Very high35 Ų3551 Ų5116%0.16424%0.244CC..Hα-helixtrans-64.3-40.4172179.259.88.100111.7T398 A401 D402 A424 K425 Y426 L430 R431 I432T398-Q428 HydrophobicContact CG2-CB 3.98Å; A401-Q428 HydrophobicContact CB-CB 3.87Å; A401-Q428 HydrophobicContact CB-CG 3.78Å; D402-Q428 PolarHBondContact OD2-NE2 3.37Å; D402-Q428 VanDerWaalsContact OD2-NE2 3.12Å; A424-Q428 WeakPolarHBondContact O-CB 3.48Å; A424-Q428 PolarHBondContact O-N 3.39Å; K425-Q428 WeakPolarHBondContact O-CB 3.45Å; K425-Q428 PolarHBondContact O-N 3.44Å; Y426-Q428 VanDerWaalsContact C-N 3.31Å; Y426-Q428 PolarHBondContact O-N 2.97Å; Q428-L430 VanDerWaalsContact C-N 3.32Å; Q428-L430 PolarHBondContact O-N 3.27Å; Q428-R431 WeakPolarHBondContact O-CB 3.36Å; Q428-R431 PolarHBondContact O-N 3.46Å; Q428-R431 VanDerWaalsContact O-N 3.17Å; Q428-I432 HydrophobicContact CG-CD1 4.03Å; Q428-I432 WeakPolarHBondContact O-CG1 3.39Å; Q428-I432 PolarHBondContact O-N 3.15Å
429L98.9Very high98.1Very high0 Ų053.6 Ų53.60%025%0.254CS..Hα-helixtrans-63.3-35.8174.2-71169.8000112.8P160 F192 A401 V404 V405 I412 K425 Y426 N427 R431 I432 E433P160-L429 HydrophobicContact CG-CD1 3.9Å; P160-L429 HydrophobicContact CG-CD2 3.99Å; F192-L429 HydrophobicContact CD1-CB 3.85Å; F192-L429 HydrophobicContact CE1-CB 3.26Å; F192-L429 HydrophobicContact CE1-CD1 4.28Å; F192-L429 HydrophobicContact CE1-CG 4.4Å; F192-L429 HydrophobicContact CE2-CB 4.04Å; F192-L429 HydrophobicContact CE2-CD1 3.6Å; F192-L429 HydrophobicContact CE2-CG 4.42Å; F192-L429 HydrophobicContact CG-CB 4.46Å; F192-L429 HydrophobicContact CZ-CB 3.38Å; F192-L429 HydrophobicContact CZ-CD1 3.47Å; F192-L429 VanDerWaalsContact CZ-CD1 3.47Å; F192-L429 HydrophobicContact CZ-CG 4.06Å; A401-L429 HydrophobicContact CB-CD2 4.1Å; A401-L429 HydrophobicContact CB-CG 3.87Å; A401-L429 WeakPolarHBondContact O-CD2 3.22Å; V404-L429 HydrophobicContact CG1-CD2 3.99Å; V405-L429 HydrophobicContact CG2-CD2 3.61Å; I412-L429 HydrophobicContact CD1-CD1 4.07Å; I412-L429 HydrophobicContact CG2-CD1 3.95Å; K425-L429 PolarHBondContact O-N 3Å; Y426-L429 WeakPolarHBondContact O-CB 3.32Å; Y426-L429 PolarHBondContact O-N 2.89Å; N427-L429 VanDerWaalsContact C-N 3.34Å; L429-R431 VanDerWaalsContact C-N 3.35Å; L429-I432 HydrophobicContact CD2-CD1 4.45Å; L429-I432 PolarHBondContact O-N 3.1Å; L429-E433 WeakPolarHBondContact O-CB 3.48Å; L429-E433 PolarHBondContact O-N 3.19Å
430L98.9Very high98Very high53 Ų5350 Ų5028%0.27726%0.26SS..Hα-helixtrans-62.5-40.2172.2-68.5171.4000112F192 K193 M196 Y426 N427 Q428 E433 E434F192-L430 HydrophobicContact CD1-CD2 3.88Å; F192-L430 HydrophobicContact CD1-CG 4.31Å; F192-L430 HydrophobicContact CE1-CD2 3.98Å; F192-L430 HydrophobicContact CE1-CG 4Å; K193-L430 HydrophobicContact CB-CD2 3.87Å; K193-L430 HydrophobicContact CG-CD2 4.46Å; M196-L430 HydrophobicContact CG-CD2 4.29Å; Y426-L430 PolarHBondContact O-N 2.96Å; N427-L430 PolarHBondContact O-N 2.72Å; Q428-L430 VanDerWaalsContact C-N 3.32Å; Q428-L430 PolarHBondContact O-N 3.27Å; L430-E433 PolarHBondContact O-N 3.4Å; L430-E434 PolarHBondContact O-N 2.73Å
431R98.8Very high97.7Very high139 Ų13952.3 Ų52.353%0.52526%0.264SS..Hα-helixtrans-66.9-40.6175.4-64.6175.5-163.31221.2112N427 Q428 L429 E433 E434 E435N427-R431 WeakPolarHBondContact O-CG 3.5Å; N427-R431 PolarHBondContact O-N 2.97Å; N427-R431 VanDerWaalsContact O-N 3.14Å; Q428-R431 WeakPolarHBondContact O-CB 3.36Å; Q428-R431 PolarHBondContact O-N 3.46Å; Q428-R431 VanDerWaalsContact O-N 3.17Å; L429-R431 VanDerWaalsContact C-N 3.35Å; R431-E433 VanDerWaalsContact C-N 3.34Å; R431-E434 PolarHBondContact O-N 2.81Å; R431-E435 PolarHBondContact O-N 2.82Å
432I98.8Very high97.6Very high1 Ų152 Ų521%0.00527%0.269CS..Hα-helixtrans-64.7-41175.9-66.6166.3000110.3Y145 L159 V405 Q428 L429 E435 L436Y145-I432 HydrophobicContact CD1-CD1 4.22Å; Y145-I432 HydrophobicContact CD1-CG1 3.96Å; Y145-I432 HydrophobicContact CD1-CG2 3.96Å; Y145-I432 HydrophobicContact CE1-CG1 4.33Å; Y145-I432 HydrophobicContact CE1-CG2 3.98Å; Y145-I432 HydrophobicContact CG-CG2 4.28Å; L159-I432 HydrophobicContact CD2-CG2 4.2Å; V405-I432 HydrophobicContact CB-CG2 4.48Å; V405-I432 HydrophobicContact CG1-CG2 3.99Å; V405-I432 HydrophobicContact CG2-CD1 4.36Å; V405-I432 HydrophobicContact CG2-CG2 4.15Å; Q428-I432 HydrophobicContact CG-CD1 4.03Å; Q428-I432 WeakPolarHBondContact O-CG1 3.39Å; Q428-I432 PolarHBondContact O-N 3.15Å; L429-I432 HydrophobicContact CD2-CD1 4.45Å; L429-I432 PolarHBondContact O-N 3.1Å; I432-E435 PolarHBondContact O-N 2.9Å; I432-L436 HydrophobicContact CG2-CD1 3.88Å; I432-L436 HydrophobicContact CG2-CG 4.3Å; I432-L436 WeakPolarHBondContact O-CB 3.45Å; I432-L436 VanDerWaalsContact O-CG 3.3Å; I432-L436 WeakPolarHBondContact O-CG 3.14Å; I432-L436 PolarHBondContact O-N 2.67Å
433E98.7Very high97.5Very high7 Ų759 Ų593%0.03330%0.3CS..Hα-helixtrans-58.2-49.7173.9178.7172.8-12800111.2L159 S191 F192 K193 L429 L430 R431 E435 L436 E437L159-E433 HydrophobicContact CD1-CB 3.65Å; L159-E433 HydrophobicContact CD1-CG 3.6Å; L159-E433 HydrophobicContact CD2-CB 4.02Å; L159-E433 HydrophobicContact CG-CB 4.5Å; S191-E433 VanDerWaalsContact CB-OE1 3.27Å; S191-E433 WeakPolarHBondContact CB-OE1 3.45Å; F192-E433 WeakPolarHBondContact CA-OE1 3.49Å; F192-E433 WeakPolarHBondContact CB-OE1 3.45Å; F192-E433 PolarHBondContact N-OE1 3.13Å; K193-E433 WeakPolarHBondContact CA-OE2 3.48Å; K193-E433 WeakPolarHBondContact CB-OE2 3.4Å; K193-E433 PolarHBondContact N-OE1 3.25Å; K193-E433 PolarHBondContact N-OE2 2.97Å; L429-E433 WeakPolarHBondContact O-CB 3.48Å; L429-E433 PolarHBondContact O-N 3.19Å; L430-E433 PolarHBondContact O-N 3.4Å; R431-E433 VanDerWaalsContact C-N 3.34Å; E433-E435 VanDerWaalsContact C-N 3.32Å; E433-E435 PolarHBondContact O-N 3.49Å; E433-L436 PolarHBondContact O-N 2.97Å; E433-L436 VanDerWaalsContact O-N 3.14Å; E433-E437 HydrophobicContact CG-CG 4.34Å; E433-E437 WeakPolarHBondContact O-CB 3.46Å; E433-E437 WeakPolarHBondContact O-CG 3.17Å; E433-E437 PolarHBondContact O-N 3.32Å
434E98.5Very high97.5Very high110 Ų11057.9 Ų57.951%0.51429%0.292SS..Hα-helixtrans-56.6-44.5176.5-175-177.5170.100112L430 R431 L436 E437 Q438L430-E434 PolarHBondContact O-N 2.73Å; R431-E434 PolarHBondContact O-N 2.81Å; E434-L436 PolarHBondContact O-N 2.97Å; E434-E437 PolarHBondContact O-N 3Å; E434-Q438 WeakPolarHBondContact O-CG 3.29Å; E434-Q438 PolarHBondContact O-N 3.06Å; E434-Q438 VanDerWaalsContact O-N 3.1Å
435E98.3Very high97.5Very high53 Ų5357.1 Ų57.125%0.24829%0.286CS..Hα-helixtrans-61.9-42.8176.9-162-160.312300111.9S143 Y145 R431 I432 E433 Q439S143-E435 VanDerWaalsContact OG-CD 3.25Å; S143-E435 PolarHBondContact OG-OE1 3.48Å; S143-E435 VanDerWaalsContact OG-OE1 3.07Å; S143-E435 PolarHBondContact OG-OE2 2.99Å; Y145-E435 WeakPolarHBondContact CE1-OE2 3.48Å; Y145-E435 VanDerWaalsContact OH-CD 3.29Å; Y145-E435 PolarHBondContact OH-OE1 2.58Å; R431-E435 PolarHBondContact O-N 2.82Å; I432-E435 PolarHBondContact O-N 2.9Å; E433-E435 VanDerWaalsContact C-N 3.32Å; E433-E435 PolarHBondContact O-N 3.49Å; E435-Q439 VanDerWaalsContact O-CG 3.31Å; E435-Q439 WeakPolarHBondContact O-CG 3.44Å; E435-Q439 PolarHBondContact O-N 3.36Å; E435-Q439 PolarHBondContact OE1-NE2 2.69Å
436L98Very high97.5Very high1 Ų157.4 Ų57.41%0.00529%0.289CS..Hα-helixtrans-71.4-32.5178.8-70.8172.8000112.7Y145 V157 L159 V405 I432 E433 E434 Q439 G440 H441 A442Y145-L436 HydrophobicContact CE2-CD2 4.04Å; V157-L436 HydrophobicContact CG2-CD1 4.17Å; V157-L436 HydrophobicContact CG2-CD2 3.77Å; L159-L436 HydrophobicContact CD2-CD1 4.29Å; L159-L436 HydrophobicContact CG-CD1 4.18Å; V405-L436 HydrophobicContact CG1-CD1 4.48Å; I432-L436 HydrophobicContact CG2-CD1 3.88Å; I432-L436 HydrophobicContact CG2-CG 4.3Å; I432-L436 WeakPolarHBondContact O-CB 3.45Å; I432-L436 VanDerWaalsContact O-CG 3.3Å; I432-L436 WeakPolarHBondContact O-CG 3.14Å; I432-L436 PolarHBondContact O-N 2.67Å; E433-L436 PolarHBondContact O-N 2.97Å; E433-L436 VanDerWaalsContact O-N 3.14Å; E434-L436 PolarHBondContact O-N 2.97Å; L436-Q439 CarbonylContact O-C 3.53Å; L436-Q439 PolarHBondContact O-N 2.99Å; L436-G440 PolarHBondContact O-N 3.5Å; L436-G440 VanDerWaalsContact O-N 3.15Å; L436-H441 PolarHBondContact O-N 2.96Å; L436-A442 HydrophobicContact CB-CB 3.97Å; L436-A442 PolarHBondContact O-N 2.83Å
437E97.8Very high97.4Very high108 Ų10862.5 Ų62.551%0.50531%0.313SS..Hα-helixtrans-64.2-45.3174.4-77.5-178.916300110.6E433 E434 Q439 G440 A442E433-E437 HydrophobicContact CG-CG 4.34Å; E433-E437 WeakPolarHBondContact O-CB 3.46Å; E433-E437 WeakPolarHBondContact O-CG 3.17Å; E433-E437 PolarHBondContact O-N 3.32Å; E434-E437 PolarHBondContact O-N 3Å; E437-Q439 PolarHBondContact O-N 3.03Å; E437-G440 PolarHBondContact O-N 2.96Å; E437-A442 HydrophobicContact CB-CB 4.32Å; E437-A442 HydrophobicContact CG-CB 3.53Å
438Q96.8Very high97.3Very high149 Ų14964.5 Ų64.570%0.69632%0.32SS*.Hα-helixtrans-59.8-29.1175-68.8171.912.200112.4E434E434-Q438 WeakPolarHBondContact O-CG 3.29Å; E434-Q438 PolarHBondContact O-N 3.06Å; E434-Q438 VanDerWaalsContact O-N 3.1Å
439Q94.7Very high97.3Very high77 Ų7763.4 Ų63.436%0.3632%0.315SS..THydrogen-bonded Turntrans-85.2-6.3175.4-64.6167.821.400113.5E435 L436 E437 H441E435-Q439 VanDerWaalsContact O-CG 3.31Å; E435-Q439 WeakPolarHBondContact O-CG 3.44Å; E435-Q439 PolarHBondContact O-N 3.36Å; E435-Q439 PolarHBondContact OE1-NE2 2.69Å; L436-Q439 CarbonylContact O-C 3.53Å; L436-Q439 PolarHBondContact O-N 2.99Å; E437-Q439 PolarHBondContact O-N 3.03Å; Q439-H441 VanDerWaalsContact C-N 3.3Å; Q439-H441 HydrophobicContact CB-CB 4.45Å; Q439-H441 PolarHBondContact O-CD2 3.12Å; Q439-H441 PolarHBondContact O-N 2.88Å
440G93.6Very high97.1Very high66 Ų6667.1 Ų67.168%0.6833%0.329SS*.THydrogen-bonded Turntrans68.326.5-174.600000113.9L436 E437L436-G440 PolarHBondContact O-N 3.5Å; L436-G440 VanDerWaalsContact O-N 3.15Å; E437-G440 PolarHBondContact O-N 2.96Å
441H92.2Very high96.8Very high115 Ų11567 Ų6753%0.53233%0.329SS..  trans-126.43.5-172.7-66.1-34000114.2L436 Q439 K443L436-H441 PolarHBondContact O-N 2.96Å; Q439-H441 VanDerWaalsContact C-N 3.3Å; Q439-H441 HydrophobicContact CB-CB 4.45Å; Q439-H441 PolarHBondContact O-CD2 3.12Å; Q439-H441 PolarHBondContact O-N 2.88Å; H441-K443 PolarHBondContact O-N 2.97Å; H441-K443 VanDerWaalsContact O-N 3.16Å
442A95.1Very high96.3Very high40 Ų4061.4 Ų61.433%0.33131%0.31SS..  trans-61.5117.6176.600000111L159 L436 E437L159-A442 HydrophobicContact CD1-CB 4.49Å; L436-A442 HydrophobicContact CB-CB 3.97Å; L436-A442 PolarHBondContact O-N 2.83Å; E437-A442 HydrophobicContact CB-CB 4.32Å; E437-A442 HydrophobicContact CG-CB 3.53Å
443K97.2Very high95.2Very high148 Ų14865.7 Ų65.764%0.64334%0.34SS*.  trans-134.5131.4174.2-68.6-173.3179.9-174.60108.7I158 L159 H441I158-K443 HydrophobicContact CG1-CB 4.14Å; I158-K443 VanDerWaalsContact CG1-O 3.22Å; I158-K443 WeakPolarHBondContact CG1-O 3.39Å; L159-K443 WeakPolarHBondContact CB-O 3.48Å; L159-K443 PolarHBondContact N-O 3.32Å; H441-K443 PolarHBondContact O-N 2.97Å; H441-K443 VanDerWaalsContact O-N 3.16Å
444Y98.2Very high93.2Very high29 Ų2974.4 Ų74.411%0.11438%0.381CS..BIsolated β-bridgetrans-101.8136.9176175.4-112.9000109.7L159 P160 V161 P186 A189 F192 A195 G446L159-Y444 HydrophobicContact CB-CD2 4.36Å; P160-Y444 WeakPolarHBondContact O-CE2 2.99Å; V161-Y444 HydrophobicContact CB-CE2 4.44Å; V161-Y444 HydrophobicContact CG2-CE1 4.09Å; V161-Y444 HydrophobicContact CG2-CE2 3.98Å; V161-Y444 WeakPolarHBondContact CG2-OH 3.39Å; P186-Y444 PolarHBondContact O-OH 2.91Å; A189-Y444 HydrophobicContact CB-CE1 3.9Å; A189-Y444 VanDerWaalsContact O-CD1 3.23Å; A189-Y444 WeakPolarHBondContact O-CD1 3.25Å; A189-Y444 VanDerWaalsContact O-CE1 3.29Å; A189-Y444 WeakPolarHBondContact O-CE1 3.48Å; F192-Y444 HydrophobicContact CB-CD2 4.07Å; F192-Y444 HydrophobicContact CB-CE2 4.43Å; F192-Y444 HydrophobicContact CD2-CE2 4.36Å; A195-Y444 HydrophobicContact CB-CE1 4.5Å; A195-Y444 HydrophobicContact CB-CE2 3.97Å; A195-Y444 WeakPolarHBondContact CB-OH 3.26Å; Y444-G446 VanDerWaalsContact C-N 3.31Å; Y444-G446 VanDerWaalsContact CE1-CA 3.45Å; Y444-G446 PolarHBondContact O-N 3.27Å
445A98.2Very high93Very high2 Ų272.6 Ų72.62%0.01737%0.374CS..  trans-62.8-36.3-175.400000113.1I158 L159 V161 G410 E447 H448 P452I158-A445 HydrophobicContact CD1-CB 3.92Å; I158-A445 HydrophobicContact CG1-CB 4.4Å; L159-A445 WeakPolarHBondContact O-CB 3.18Å; L159-A445 PolarHBondContact O-N 3.22Å; V161-A445 HydrophobicContact CG2-CB 4.15Å; G410-A445 WeakPolarHBondContact O-CB 3.4Å; A445-E447 PolarHBondContact O-N 2.89Å; A445-H448 CarbonylContact O-C 3.6Å; A445-H448 WeakPolarHBondContact O-CA 3.4Å; A445-H448 WeakPolarHBondContact O-CB 3.48Å; A445-H448 PolarHBondContact O-N 3.24Å; A445-P452 HydrophobicContact CB-CB 4.23Å
446G98.1Very high92.7Very high7 Ų773.6 Ų73.67%0.07238%0.381CS..G310 helixtrans49.5-131.6175.300000113.8V161 V187 Y444 H448 F449V161-G446 WeakPolarHBondContact CG2-O 3.35Å; V187-G446 CarbonylContact O-C 3.57Å; V187-G446 WeakPolarHBondContact O-CA 3.38Å; Y444-G446 VanDerWaalsContact C-N 3.31Å; Y444-G446 VanDerWaalsContact CE1-CA 3.45Å; Y444-G446 PolarHBondContact O-N 3.27Å; G446-H448 PolarHBondContact O-N 3.36Å; G446-H448 VanDerWaalsContact O-N 3.14Å; G446-F449 WeakPolarHBondContact O-CB 3.38Å; G446-F449 PolarHBondContact O-N 3.08Å; G446-F449 VanDerWaalsContact O-N 3.08Å
447E97.2Very high92.4Very high107 Ų10777.7 Ų77.750%0.540%0.401SS..G310 helixtrans-61.3-19.5177.5-63.9-68.9175.400113.3V187 A445 F449V187-E447 PolarHBondContact O-N 2.94Å; V187-E447 VanDerWaalsContact O-N 3.14Å; A445-E447 PolarHBondContact O-N 2.89Å; E447-F449 VanDerWaalsContact C-N 3.29Å; E447-F449 PolarHBondContact O-N 3.32Å
448H97Very high92.1Very high107 Ų10775.9 Ų75.950%0.49540%0.395SS..G310 helixtrans-89.315.1176.5-55.7-74.8000113.3A445 G446 R450 N451 P452A445-H448 CarbonylContact O-C 3.6Å; A445-H448 WeakPolarHBondContact O-CA 3.4Å; A445-H448 WeakPolarHBondContact O-CB 3.48Å; A445-H448 PolarHBondContact O-N 3.24Å; G446-H448 PolarHBondContact O-N 3.36Å; G446-H448 VanDerWaalsContact O-N 3.14Å; H448-R450 PolarHBondContact O-N 3Å; H448-N451 CarbonylContact O-C 3.59Å; H448-N451 PolarHBondContact O-N 2.68Å; H448-P452 WeakPolarHBondContact O-CA 3.37Å; H448-P452 VanDerWaalsContact O-N 3.07Å
449F97.5Very high91.8Very high13 Ų1371.3 Ų71.36%0.05738%0.377CS..THydrogen-bonded Turntrans-46.1-36.1-176.972.4-75.8000114.9V161 M185 V187 V309 Q411 G446 E447V161-F449 HydrophobicContact CB-CB 4.11Å; V161-F449 HydrophobicContact CG2-CB 3.72Å; M185-F449 HydrophobicContact CE-CD2 3.58Å; M185-F449 HydrophobicContact CE-CE2 3.82Å; M185-F449 HydrophobicContact CE-CG 4.38Å; V187-F449 HydrophobicContact CG1-CD1 3.96Å; V187-F449 HydrophobicContact CG1-CE1 4.25Å; V187-F449 HydrophobicContact CG1-CG 4.39Å; V309-F449 HydrophobicContact CB-CZ 4.16Å; V309-F449 HydrophobicContact CG2-CZ 4Å; Q411-F449 HydrophobicContact CG-CB 3.8Å; Q411-F449 HydrophobicContact CG-CD2 3.73Å; Q411-F449 HydrophobicContact CG-CG 4.28Å; Q411-F449 WeakPolarHBondContact CG-O 3.38Å; Q411-F449 PolarHBondContact NE2-O 2.76Å; Q411-F449 VanDerWaalsContact OE1-CD2 3.29Å; G446-F449 WeakPolarHBondContact O-CB 3.38Å; G446-F449 PolarHBondContact O-N 3.08Å; G446-F449 VanDerWaalsContact O-N 3.08Å; E447-F449 VanDerWaalsContact C-N 3.29Å; E447-F449 PolarHBondContact O-N 3.32Å
450R96.3Very high91.6Very high78 Ų7870.9 Ų70.929%0.29438%0.378SS..THydrogen-bonded Turntrans-70.4-36.1178-63.5175.767.1177.66113.5D331 N357 G385 H448D331-R450 PolarHBondContact O-NH1 2.94Å; N357-R450 PolarHBondContact ND2-NH2 3.31Å; N357-R450 VanDerWaalsContact ND2-NH2 3.19Å; G385-R450 WeakPolarHBondContact CA-O 3.37Å; H448-R450 PolarHBondContact O-N 3Å
451N92.1Very high91.5Very high51 Ų5171.3 Ų71.327%0.27336%0.356SS..  trans-144.471.8-173.1-73.3-56.8000110.1H448 S453 Q454H448-N451 CarbonylContact O-C 3.59Å; H448-N451 PolarHBondContact O-N 2.68Å; N451-S453 PolarHBondContact O-N 3.22Å; N451-Q454 HydrophobicContact CB-CG 4.12Å; N451-Q454 PolarHBondContact O-N 2.91Å; N451-Q454 VanDerWaalsContact O-N 3.15Å
452P88.8Confident91.4Very high20 Ų2067.9 Ų67.913%0.1334%0.342CS..THydrogen-bonded Turntrans-67.3-9.3-172.426-36.9000115I158 A408 A445 H448 Q454I158-P452 HydrophobicContact CD1-CB 3.42Å; I158-P452 VanDerWaalsContact CD1-CB 3.42Å; I158-P452 HydrophobicContact CG1-CB 4.47Å; I158-P452 HydrophobicContact CG2-CB 3.82Å; I158-P452 HydrophobicContact CG2-CG 4.08Å; A408-P452 VanDerWaalsContact O-CG 3.29Å; A408-P452 WeakPolarHBondContact O-CG 3.34Å; A445-P452 HydrophobicContact CB-CB 4.23Å; H448-P452 WeakPolarHBondContact O-CA 3.37Å; H448-P452 VanDerWaalsContact O-N 3.07Å; P452-Q454 VanDerWaalsContact C-N 3.29Å
453S75.9Confident91.1Very high92 Ų9270.3 Ų70.364%0.64334%0.343SS*.THydrogen-bonded Turntrans-81.2-6176.252.50000114N451N451-S453 PolarHBondContact O-N 3.22Å
454Q56.7Low90.5Very high189 Ų18963.2 Ų63.288%0.88332%0.316SS*.  trans-84.80-179.5-70.3-172.4-4.300113.1N451 P452N451-Q454 HydrophobicContact CB-CG 4.12Å; N451-Q454 PolarHBondContact O-N 2.91Å; N451-Q454 VanDerWaalsContact O-N 3.15Å; P452-Q454 VanDerWaalsContact C-N 3.29Å

Retrieved 454 of 454 residues in 753.6 ms (Link to these results)