A0A077YXL1_TRITR Loading...

Sugar tr domain containing protein

AlphaFold DB , UniProt , Accession A0A077YXL1, Species TRITR (Trichuris trichiura, Whipworm), Gene n/a, Length 516 aa.

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(Predicted Aligned Error values between residue pairs)

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Site	Residue	pLDDT	pLDDT confidence	pLDDT₁₀	pLDDT10 confidence	SASA	SASA [Å²]	SASA₁₀	SASA10 [Å²]	RSA	RSA unformatted	RSA₁₀	RSA10 unformatted	Surface	Surface10 (not used)	Disorder (not used)	Disorder	Sec. str.	Secondary structure	Isomer	Phi (φ)	Psi (ψ)	Omega (ω)	Chi 1 (χ₁)	Chi 2 (χ₂)	Chi 3 (χ₃)	Chi 4 (χ₄)	Chi 5 (χ₅)	Tau (τ)	Contacts (colored by PAE)	Contact details
1	M	39.4	Very low	35.5	Very low	214 Å²	214	130.9 Å²	130.9	100%	1.054	72%	0.724	S	S	*	*				0	-28	0	-76.7	178.5	66	0	0	115	A3	M1-A3 PolarHBondContact O-N 3.16Å
2	G	37.9	Very low	36.4	Very low	57 Å²	57	127.3 Å²	127.3	59%	0.588	71%	0.709	S	S	*	*	H	α-helix	trans	-73.8	-21.7	-175.4	0	0	0	0	0	117.2
3	A	37.9	Very low	37.7	Very low	87 Å²	87	122.7 Å²	122.7	72%	0.719	69%	0.688	S	S	*	*	H	α-helix	trans	-79.4	-36	-179.7	0	0	0	0	0	112.9	M1 S7	M1-A3 PolarHBondContact O-N 3.16Å; A3-S7 PolarHBondContact O-N 3.43Å
4	E	36.1	Very low	39.8	Very low	159 Å²	159	117.9 Å²	117.9	74%	0.743	66%	0.66	S	S	*	*	H	α-helix	trans	-73.3	-27.4	176.7	-83.5	178.7	135.5	0	0	113.2
5	A	34.8	Very low	41.8	Very low	59 Å²	59	110.1 Å²	110.1	49%	0.488	62%	0.616	S	S	.	*	H	α-helix	trans	-72	-37	175.8	0	0	0	0	0	112.2	K8	A5-K8 PolarHBondContact O-N 3.35Å
6	K	30	Very low	43.3	Very low	166 Å²	166	104.3 Å²	104.3	72%	0.722	58%	0.583	S	S	*	*	H	α-helix	trans	-72.8	-27.3	177.9	-80.2	-176	174.3	-179.2	0	113.3	K8 L9	K6-K8 VanDerWaalsContact C-N 3.27Å; K6-K8 PolarHBondContact O-N 3.16Å; K6-L9 PolarHBondContact O-N 3.15Å
7	S	33.1	Very low	44.8	Very low	84 Å²	84	103 Å²	103	59%	0.587	58%	0.582	S	S	*	*	H	α-helix	trans	-68.3	-22	175.3	173.2	0	0	0	0	113.7	A3	A3-S7 PolarHBondContact O-N 3.43Å
8	K	30.7	Very low	46	Very low	183 Å²	183	98.1 Å²	98.1	80%	0.796	56%	0.555	S	S	*	*	T	Hydrogen-bonded Turn	trans	-88.5	-11.5	-179.7	-75.7	-175.4	177	177.5	0	114.2	A5 K6	A5-K8 PolarHBondContact O-N 3.35Å; K6-K8 VanDerWaalsContact C-N 3.27Å; K6-K8 PolarHBondContact O-N 3.16Å
9	L	32	Very low	47.3	Very low	148 Å²	148	93.2 Å²	93.2	78%	0.775	53%	0.527	S	S	*	.	S	Bend	trans	-96.7	-10.1	-175.9	-93.6	138.4	0	0	0	114.2	K6	K6-L9 PolarHBondContact O-N 3.15Å
10	T	35.6	Very low	48.4	Very low	118 Å²	118	92.7 Å²	92.7	72%	0.724	52%	0.517	S	S	*	.	S	Bend	trans	-85.4	-17.1	-179.4	41.2	0	0	0	0	114.4	T12	T10-T12 PolarHBondContact O-N 3.48Å
11	E	42.9	Very low	49.7	Very low	165 Å²	165	91.4 Å²	91.4	77%	0.771	51%	0.513	S	S	*	.	S	Bend	trans	-82.9	104.4	166.8	-73.5	-176.8	173.2	0	0	107.5	P13	E11-P13 WeakPolarHBondContact O-CD 3.42Å; E11-P13 VanDerWaalsContact O-N 3.09Å
12	T	46.9	Very low	51.8	Low	88 Å²	88	82.2 Å²	82.2	54%	0.54	47%	0.474	S	S	.	.			trans	-48.8	121.3	164.6	45.5	0	0	0	0	107.6	T10 D14	T10-T12 PolarHBondContact O-N 3.48Å; T12-D14 PolarHBondContact O-N 2.99Å
13	P	53.3	Low	54.1	Low	67 Å²	67	82.5 Å²	82.5	44%	0.435	47%	0.471	S	S	.	.			trans	-58.9	107.4	-176.6	20.3	-30.8	0	0	0	109.2	E11 V274	E11-P13 WeakPolarHBondContact O-CD 3.42Å; E11-P13 VanDerWaalsContact O-N 3.09Å; P13-V274 HydrophobicContact CB-CG2 3.9Å; P13-V274 HydrophobicContact CG-CG2 3.71Å
14	D	66.3	Low	56.5	Low	56 Å²	56	78.6 Å²	78.6	30%	0.299	44%	0.438	S	S	.	.			trans	-70.6	138.4	173.2	-166.3	-16.6	0	0	0	107.6	T12 E16 S17 R237	T12-D14 PolarHBondContact O-N 2.99Å; D14-E16 PolarHBondContact O-N 2.97Å; D14-E16 PolarHBondContact OD1-N 3.04Å; D14-S17 WeakPolarHBondContact O-CB 3.49Å; D14-S17 PolarHBondContact O-N 3.17Å; D14-S17 PolarHBondContact O-OG 2.97Å; D14-R237 IonicContact OD1-NH1 3.48Å; D14-R237 IonicContact OD2-NH1 3.78Å; D14-R237 PolarHBondContact OD2-NH1 3.37Å
15	I	69.7	Low	58.8	Low	1 Å²	1	71.5 Å²	71.5	1%	0.005	40%	0.404	C	S	.	.	G	3₁₀ helix	trans	-47.2	-38.2	175.2	-69.8	172.9	0	0	0	110.6	S17 T18 P236 V240 V274 T278	I15-S17 VanDerWaalsContact C-N 3.27Å; I15-S17 PolarHBondContact O-N 3.18Å; I15-T18 PolarHBondContact O-N 3.49Å; I15-T18 VanDerWaalsContact O-N 3.08Å; I15-T18 PolarHBondContact O-OG1 3.24Å; I15-P236 HydrophobicContact CG2-CB 4.04Å; I15-V240 HydrophobicContact CD1-CB 4.34Å; I15-V240 HydrophobicContact CD1-CG2 3.89Å; I15-V274 HydrophobicContact CB-CG1 4.18Å; I15-V274 HydrophobicContact CD1-CG1 4.17Å; I15-V274 HydrophobicContact CG1-CG1 3.16Å; I15-T278 HydrophobicContact CD1-CG2 3.96Å; I15-T278 VanDerWaalsContact CD1-OG1 3.26Å; I15-T278 WeakPolarHBondContact CD1-OG1 3.48Å; I15-T278 WeakPolarHBondContact CG1-OG1 3.22Å
16	E	67.1	Low	61.3	Low	17 Å²	17	73.4 Å²	73.4	8%	0.079	41%	0.41	C	S	.	.	G	3₁₀ helix	trans	-60.2	-33.7	-180	-63.4	-175.3	173.4	0	0	113.6	D14 T18 L19 R185 R237	D14-E16 PolarHBondContact O-N 2.97Å; D14-E16 PolarHBondContact OD1-N 3.04Å; E16-T18 PolarHBondContact O-N 2.95Å; E16-L19 PolarHBondContact O-N 3.47Å; E16-R185 VanDerWaalsContact CD-NH2 3.28Å; E16-R185 IonicContact OE1-NH2 2.74Å; E16-R185 IonicContact OE2-CZ 3.65Å; E16-R185 IonicContact OE2-NH1 3.02Å; E16-R185 IonicContact OE2-NH2 3.51Å; E16-R185 PolarHBondContact OE2-NH2 2.71Å; E16-R237 IonicContact OE1-CZ 2.72Å; E16-R237 IonicContact OE1-NH1 3.44Å; E16-R237 PolarHBondContact OE1-NH1 2.86Å; E16-R237 IonicContact OE2-NH1 3.84Å
17	S	67.2	Low	64.1	Low	82 Å²	82	67.1 Å²	67.1	57%	0.573	39%	0.389	S	S	*	.	G	3₁₀ helix	trans	-68.1	-21.6	178.9	70.8	0	0	0	0	112.6	D14 I15	D14-S17 WeakPolarHBondContact O-CB 3.49Å; D14-S17 PolarHBondContact O-N 3.17Å; D14-S17 PolarHBondContact O-OG 2.97Å; I15-S17 VanDerWaalsContact C-N 3.27Å; I15-S17 PolarHBondContact O-N 3.18Å
18	T	67.3	Low	66.6	Low	15 Å²	15	63.1 Å²	63.1	9%	0.092	36%	0.361	C	S	.	.	G	3₁₀ helix	trans	-91	-7.2	-179.8	75.1	0	0	0	0	113.2	I15 E16 Y20 L266	I15-T18 PolarHBondContact O-N 3.49Å; I15-T18 VanDerWaalsContact O-N 3.08Å; I15-T18 PolarHBondContact O-OG1 3.24Å; E16-T18 PolarHBondContact O-N 2.95Å; T18-Y20 VanDerWaalsContact O-CD2 3.26Å; T18-Y20 WeakPolarHBondContact O-CD2 3.3Å; T18-Y20 WeakPolarHBondContact O-CE2 3.45Å; T18-Y20 PolarHBondContact O-N 2.88Å; T18-L266 HydrophobicContact CG2-CD1 4.21Å
19	L	69.8	Low	69.2	Low	5 Å²	5	56.8 Å²	56.8	3%	0.026	33%	0.332	C	S	.	.			trans	-84.7	90.1	176.6	-68.5	170.5	0	0	0	110	E16 E178 I181 I255	E16-L19 PolarHBondContact O-N 3.47Å; L19-E178 WeakPolarHBondContact CD1-O 3.27Å; L19-I181 WeakPolarHBondContact O-CG1 3.47Å; L19-I255 HydrophobicContact CD2-CD1 3.88Å; L19-I255 HydrophobicContact CD2-CG2 3.89Å
20	Y	71	Confident	71.9	Confident	83 Å²	83	51.5 Å²	51.5	33%	0.325	31%	0.31	S	S	.	.			trans	-70.4	138.4	172.8	-58	-86.4	0	0	0	111.6	T18 G22 Q25 L256 N259 K261 H264	T18-Y20 VanDerWaalsContact O-CD2 3.26Å; T18-Y20 WeakPolarHBondContact O-CD2 3.3Å; T18-Y20 WeakPolarHBondContact O-CE2 3.45Å; T18-Y20 PolarHBondContact O-N 2.88Å; Y20-G22 PolarHBondContact O-N 2.89Å; Y20-Q25 VanDerWaalsContact O-CD 3.26Å; Y20-Q25 PolarHBondContact O-NE2 2.93Å; Y20-Q25 PolarHBondContact O-OE1 2.93Å; Y20-Q25 VanDerWaalsContact O-OE1 3.11Å; Y20-L256 HydrophobicContact CD2-CD2 4.45Å; Y20-N259 PolarHBondContact O-ND2 3.41Å; Y20-K261 HydrophobicContact CD1-CD 4.39Å; Y20-K261 HydrophobicContact CD2-CD 4.08Å; Y20-K261 HydrophobicContact CG-CD 3.69Å; Y20-H264 HydrophobicContact CD2-CB 4.3Å; Y20-H264 HydrophobicContact CE2-CB 3.38Å; Y20-H264 AromaticContact CE2-CD2 3.89Å; Y20-H264 AromaticContact CE2-CG 3.63Å; Y20-H264 AromaticContact CZ-CD2 3.9Å; Y20-H264 AromaticContact CZ-CG 3.6Å; Y20-H264 AromaticContact CZ-ND1 3.89Å; Y20-H264 PolarHBondContact OH-ND1 3.43Å
21	C	74.8	Confident	74.3	Confident	65 Å²	65	46.6 Å²	46.6	44%	0.439	28%	0.278	S	S	.	.			trans	-57.4	134.8	169.7	-70.9	0	0	0	0	111.3	K261	C21-K261 PolarHBondContact O-NZ 2.88Å
22	G	83.8	Confident	76.4	Confident	22 Å²	22	39.3 Å²	39.3	23%	0.227	24%	0.244	C	C	.	.	S	Bend	trans	-169.1	-164.7	174.6	0	0	0	0	0	110.9	Y20 Y24 Q25 V26 N259	Y20-G22 PolarHBondContact O-N 2.89Å; G22-Y24 PolarHBondContact O-N 3.5Å; G22-Q25 PolarHBondContact O-N 3.08Å; G22-Q25 VanDerWaalsContact O-N 3.13Å; G22-Q25 PolarHBondContact O-OE1 3.4Å; G22-V26 PolarHBondContact O-N 2.83Å; G22-V26 VanDerWaalsContact O-N 3.14Å; G22-N259 WeakPolarHBondContact CA-OD1 3.4Å
23	A	86.8	Confident	78.4	Confident	63 Å²	63	36.1 Å²	36.1	52%	0.521	22%	0.223	S	C	.	.	H	α-helix	trans	-56.9	-32	-177.1	0	0	0	0	0	113.5	V26 A27 V258 N259	A23-V26 PolarHBondContact O-N 3.23Å; A23-A27 PolarHBondContact O-N 3.45Å; A23-V258 HydrophobicContact CB-CG1 4.22Å; A23-N259 PolarHBondContact N-OD1 3.12Å; A23-N259 VanDerWaalsContact N-OD1 3.13Å
24	Y	86.6	Confident	80.1	Confident	5 Å²	5	34 Å²	34	2%	0.02	21%	0.208	C	C	.	.	H	α-helix	trans	-63.7	-46.2	177	-172.1	-86.9	0	0	0	112	G22 V26 A27 A28 L232 K233 I255 V258 N259	G22-Y24 PolarHBondContact O-N 3.5Å; Y24-V26 VanDerWaalsContact C-N 3.33Å; Y24-A27 PolarHBondContact O-N 3.26Å; Y24-A28 PolarHBondContact O-N 3.27Å; Y24-L232 HydrophobicContact CD2-CD2 3.98Å; Y24-L232 HydrophobicContact CE1-CD2 4.19Å; Y24-L232 HydrophobicContact CE2-CD2 3.57Å; Y24-L232 HydrophobicContact CG-CD2 4.45Å; Y24-K233 PolarHBondContact OH-N 3.41Å; Y24-K233 PolarHBondContact OH-O 3.43Å; Y24-I255 HydrophobicContact CD1-CB 4.42Å; Y24-I255 HydrophobicContact CD1-CD1 4.35Å; Y24-I255 HydrophobicContact CD1-CG1 3.81Å; Y24-I255 HydrophobicContact CD1-CG2 3.98Å; Y24-I255 HydrophobicContact CD2-CG1 4.03Å; Y24-I255 HydrophobicContact CE1-CD1 3.87Å; Y24-I255 HydrophobicContact CE1-CG1 3.61Å; Y24-I255 HydrophobicContact CE2-CG1 3.82Å; Y24-I255 HydrophobicContact CG-CB 4.37Å; Y24-I255 HydrophobicContact CG-CG1 4.02Å; Y24-I255 HydrophobicContact CG-CG2 4.09Å; Y24-V258 HydrophobicContact CD2-CB 4.44Å; Y24-V258 HydrophobicContact CD2-CG1 4.43Å; Y24-N259 WeakPolarHBondContact CB-OD1 3.32Å; Y24-N259 PolarHBondContact N-OD1 2.9Å
25	Q	86.1	Confident	81.1	Confident	9 Å²	9	32.2 Å²	32.2	4%	0.042	20%	0.2	C	C	.	.	H	α-helix	trans	-69	-33.1	178.1	-72.1	79.4	5.6	0	0	111.7	Y20 G22 A27 A28 Y29 N179 N259	Y20-Q25 VanDerWaalsContact O-CD 3.26Å; Y20-Q25 PolarHBondContact O-NE2 2.93Å; Y20-Q25 PolarHBondContact O-OE1 2.93Å; Y20-Q25 VanDerWaalsContact O-OE1 3.11Å; G22-Q25 PolarHBondContact O-N 3.08Å; G22-Q25 VanDerWaalsContact O-N 3.13Å; G22-Q25 PolarHBondContact O-OE1 3.4Å; Q25-A27 VanDerWaalsContact C-N 3.34Å; Q25-A28 PolarHBondContact O-N 3.44Å; Q25-Y29 WeakPolarHBondContact O-CB 3.28Å; Q25-Y29 PolarHBondContact O-N 2.88Å; Q25-N179 VanDerWaalsContact CG-O 3.24Å; Q25-N179 WeakPolarHBondContact CG-O 3.37Å; Q25-N259 PolarHBondContact NE2-ND2 3.32Å; Q25-N259 PolarHBondContact OE1-ND2 3.16Å; Q25-N259 PolarHBondContact OE1-OD1 3.13Å
26	V	87.1	Confident	82	Confident	100 Å²	100	33 Å²	33	61%	0.606	21%	0.205	S	C	*	.	H	α-helix	trans	-62.4	-43.9	172.1	176.2	0	0	0	0	110.4	G22 A23 Y24 Y29 A30	G22-V26 PolarHBondContact O-N 2.83Å; G22-V26 VanDerWaalsContact O-N 3.14Å; A23-V26 PolarHBondContact O-N 3.23Å; Y24-V26 VanDerWaalsContact C-N 3.33Å; V26-Y29 PolarHBondContact O-N 3.47Å; V26-A30 WeakPolarHBondContact O-CB 3.48Å; V26-A30 PolarHBondContact O-N 3.15Å
27	A	87.8	Confident	83.1	Confident	34 Å²	34	33.8 Å²	33.8	28%	0.281	21%	0.208	S	C	.	.	H	α-helix	trans	-65	-40.9	175.3	0	0	0	0	0	112.6	A23 Y24 Q25 Y29 A30 F31 L232	A23-A27 PolarHBondContact O-N 3.45Å; Y24-A27 PolarHBondContact O-N 3.26Å; Q25-A27 VanDerWaalsContact C-N 3.34Å; A27-Y29 VanDerWaalsContact C-N 3.34Å; A27-A30 PolarHBondContact O-N 2.94Å; A27-F31 WeakPolarHBondContact O-CB 3.38Å; A27-F31 PolarHBondContact O-N 3.35Å; A27-L232 HydrophobicContact CB-CD2 4.07Å
28	A	85.1	Confident	84.2	Confident	0 Å²	0	30.5 Å²	30.5	0%	0	19%	0.185	C	C	.	.	H	α-helix	trans	-63.5	-39	174.4	0	0	0	0	0	112.5	Y24 Q25 F31 F32 Y175 L232	Y24-A28 PolarHBondContact O-N 3.27Å; Q25-A28 PolarHBondContact O-N 3.44Å; A28-F31 PolarHBondContact O-N 2.88Å; A28-F32 PolarHBondContact O-N 2.84Å; A28-Y175 HydrophobicContact CB-CE1 3.94Å; A28-L232 HydrophobicContact CB-CD1 4.24Å
29	Y	86.1	Confident	85.1	Confident	50 Å²	50	31.9 Å²	31.9	20%	0.196	19%	0.191	C	C	.	.	H	α-helix	trans	-69	-40.5	175.1	-176	-98.8	0	0	0	111.9	Q25 V26 A27 F32 Q33 L176 I180 L188 A192	Q25-Y29 WeakPolarHBondContact O-CB 3.28Å; Q25-Y29 PolarHBondContact O-N 2.88Å; V26-Y29 PolarHBondContact O-N 3.47Å; A27-Y29 VanDerWaalsContact C-N 3.34Å; Y29-F32 WeakPolarHBondContact O-CB 3.35Å; Y29-F32 PolarHBondContact O-N 3.39Å; Y29-Q33 WeakPolarHBondContact O-CB 3.43Å; Y29-Q33 PolarHBondContact O-N 3.46Å; Y29-L176 HydrophobicContact CD2-CD1 4.06Å; Y29-I180 HydrophobicContact CD2-CD1 4.25Å; Y29-L188 HydrophobicContact CD2-CD2 4.23Å; Y29-L188 HydrophobicContact CE2-CB 3.95Å; Y29-L188 HydrophobicContact CE2-CD2 3.62Å; Y29-L188 HydrophobicContact CE2-CG 4.32Å; Y29-A192 HydrophobicContact CE1-CB 4.03Å; Y29-A192 HydrophobicContact CE2-CB 3.62Å; Y29-A192 WeakPolarHBondContact OH-CB 3.44Å; Y29-A192 PolarHBondContact OH-N 3.33Å
30	A	88.1	Confident	86.1	Confident	36 Å²	36	31.7 Å²	31.7	30%	0.298	19%	0.19	S	C	.	.	H	α-helix	trans	-61.8	-44.9	173.4	0	0	0	0	0	111.2	V26 A27 F32 Q33 L34	V26-A30 WeakPolarHBondContact O-CB 3.48Å; V26-A30 PolarHBondContact O-N 3.15Å; A27-A30 PolarHBondContact O-N 2.94Å; A30-F32 PolarHBondContact O-N 3.15Å; A30-Q33 PolarHBondContact O-N 3.46Å; A30-L34 VanDerWaalsContact O-CG 3.29Å; A30-L34 WeakPolarHBondContact O-CG 3.3Å; A30-L34 PolarHBondContact O-N 2.94Å
31	F	87.5	Confident	87.1	Confident	16 Å²	16	27.8 Å²	27.8	7%	0.07	18%	0.175	C	C	.	.	H	α-helix	trans	-55.1	-51.7	172.5	166.9	-108.9	0	0	0	111.8	A27 A28 Q33 L34 C35 I172 Y175 A225 I228 I229 L232	A27-F31 WeakPolarHBondContact O-CB 3.38Å; A27-F31 PolarHBondContact O-N 3.35Å; A28-F31 PolarHBondContact O-N 2.88Å; F31-Q33 VanDerWaalsContact C-N 3.26Å; F31-Q33 PolarHBondContact O-N 3.49Å; F31-L34 PolarHBondContact O-N 3.35Å; F31-C35 VanDerWaalsContact CE2-SG 3.53Å; F31-C35 PolarHBondContact O-N 2.82Å; F31-C35 VanDerWaalsContact O-N 3.11Å; F31-C35 PolarHBondContact O-SG 3.29Å; F31-I172 HydrophobicContact CE1-CG1 4Å; F31-I172 HydrophobicContact CE1-CG2 4.36Å; F31-I172 HydrophobicContact CZ-CD1 4.22Å; F31-I172 HydrophobicContact CZ-CG1 4.07Å; F31-Y175 HydrophobicContact CD1-CD1 4.2Å; F31-Y175 HydrophobicContact CD1-CE1 4.22Å; F31-Y175 HydrophobicContact CE1-CD1 4.31Å; F31-A225 HydrophobicContact CD2-CB 3.85Å; F31-A225 VanDerWaalsContact CD2-O 3.24Å; F31-A225 WeakPolarHBondContact CD2-O 3.33Å; F31-A225 HydrophobicContact CE2-CB 4Å; F31-A225 WeakPolarHBondContact CE2-O 3.47Å; F31-I228 HydrophobicContact CB-CB 4.38Å; F31-I228 HydrophobicContact CB-CG2 3.84Å; F31-I229 HydrophobicContact CD1-CD1 4.14Å; F31-I229 HydrophobicContact CD2-CB 3.92Å; F31-I229 HydrophobicContact CE1-CD1 3.8Å; F31-I229 HydrophobicContact CE1-CG1 4.36Å; F31-I229 HydrophobicContact CE2-CB 3.61Å; F31-I229 HydrophobicContact CE2-CD1 4.39Å; F31-I229 HydrophobicContact CE2-CG1 4.18Å; F31-I229 HydrophobicContact CE2-CG2 4.09Å; F31-I229 HydrophobicContact CZ-CB 3.95Å; F31-I229 HydrophobicContact CZ-CD1 3.94Å; F31-I229 HydrophobicContact CZ-CG1 3.98Å; F31-L232 HydrophobicContact CB-CD1 4.19Å
32	F	85.8	Confident	87.8	Confident	11 Å²	11	25.7 Å²	25.7	5%	0.048	16%	0.16	C	C	.	.	H	α-helix	trans	-53.7	-45.2	176	169.8	-89.3	0	0	0	111.9	A28 Y29 A30 C35 C36 I172 L176 F189 A192	A28-F32 PolarHBondContact O-N 2.84Å; Y29-F32 WeakPolarHBondContact O-CB 3.35Å; Y29-F32 PolarHBondContact O-N 3.39Å; A30-F32 PolarHBondContact O-N 3.15Å; F32-C35 PolarHBondContact O-N 2.97Å; F32-C36 VanDerWaalsContact CZ-SG 3.56Å; F32-C36 PolarHBondContact O-N 3.32Å; F32-C36 PolarHBondContact O-SG 3.47Å; F32-C36 VanDerWaalsContact O-SG 3.33Å; F32-I172 HydrophobicContact CB-CG2 4.03Å; F32-I172 HydrophobicContact CD2-CG2 3.35Å; F32-I172 HydrophobicContact CE2-CG2 4.1Å; F32-I172 HydrophobicContact CG-CG2 4.05Å; F32-L176 HydrophobicContact CB-CB 4.47Å; F32-L176 HydrophobicContact CB-CD1 3.88Å; F32-L176 HydrophobicContact CB-CD2 4.43Å; F32-L176 HydrophobicContact CB-CG 4.49Å; F32-L176 HydrophobicContact CD1-CD2 3.79Å; F32-L176 HydrophobicContact CD2-CB 3.76Å; F32-L176 HydrophobicContact CD2-CD1 4.45Å; F32-L176 HydrophobicContact CD2-CD2 3.7Å; F32-L176 HydrophobicContact CD2-CG 4.16Å; F32-L176 HydrophobicContact CE1-CD2 3.92Å; F32-L176 HydrophobicContact CE2-CB 4.35Å; F32-L176 HydrophobicContact CE2-CD2 3.89Å; F32-L176 HydrophobicContact CG-CB 4.22Å; F32-L176 HydrophobicContact CG-CD1 4.07Å; F32-L176 HydrophobicContact CG-CD2 3.7Å; F32-L176 HydrophobicContact CG-CG 4.21Å; F32-L176 HydrophobicContact CZ-CD2 4Å; F32-F189 AromaticContact CE2-CE1 3.87Å; F32-F189 HydrophobicContact CE2-CE1 3.87Å; F32-F189 AromaticContact CZ-CD1 3.88Å; F32-F189 HydrophobicContact CZ-CD1 3.88Å; F32-F189 AromaticContact CZ-CE1 3.67Å; F32-F189 HydrophobicContact CZ-CE1 3.67Å; F32-A192 HydrophobicContact CE1-CB 4.39Å
33	Q	89.6	Confident	88	Confident	21 Å²	21	26.2 Å²	26.2	10%	0.098	16%	0.157	C	C	.	.	H	α-helix	trans	-67.8	-42.8	-178.1	-171	57.1	29.6	0	0	112.9	Y29 A30 F31 C35 C36 F37 G193	Y29-Q33 WeakPolarHBondContact O-CB 3.43Å; Y29-Q33 PolarHBondContact O-N 3.46Å; A30-Q33 PolarHBondContact O-N 3.46Å; F31-Q33 VanDerWaalsContact C-N 3.26Å; F31-Q33 PolarHBondContact O-N 3.49Å; Q33-C35 VanDerWaalsContact C-N 3.28Å; Q33-C35 PolarHBondContact O-N 3.27Å; Q33-C36 CarbonylContact O-C 3.58Å; Q33-C36 WeakPolarHBondContact O-CB 3.5Å; Q33-C36 PolarHBondContact O-N 2.98Å; Q33-C36 VanDerWaalsContact O-N 3.14Å; Q33-F37 HydrophobicContact CG-CD1 4.27Å; Q33-F37 HydrophobicContact CG-CE1 3.91Å; Q33-F37 HydrophobicContact CG-CE2 4.13Å; Q33-F37 HydrophobicContact CG-CZ 3.8Å; Q33-F37 VanDerWaalsContact NE2-CD1 3.29Å; Q33-F37 WeakPolarHBondContact O-CG 3.5Å; Q33-F37 PolarHBondContact O-N 3.38Å; Q33-G193 PolarHBondContact NE2-O 2.91Å
34	L	89.6	Confident	88.2	Confident	22 Å²	22	23.4 Å²	23.4	12%	0.115	13%	0.134	C	C	.	.	H	α-helix	trans	-63.5	-35.5	177.8	-66.8	173.9	0	0	0	112	A30 F31 F37 T38 I221 L224 A225 I228	A30-L34 VanDerWaalsContact O-CG 3.29Å; A30-L34 WeakPolarHBondContact O-CG 3.3Å; A30-L34 PolarHBondContact O-N 2.94Å; F31-L34 PolarHBondContact O-N 3.35Å; L34-F37 HydrophobicContact CD2-CD2 4.2Å; L34-F37 WeakPolarHBondContact O-CB 3.47Å; L34-F37 PolarHBondContact O-N 3.43Å; L34-T38 PolarHBondContact O-N 2.87Å; L34-T38 PolarHBondContact O-OG1 3.02Å; L34-I221 HydrophobicContact CD2-CD1 3.58Å; L34-I221 HydrophobicContact CD2-CG1 3.63Å; L34-L224 HydrophobicContact CD1-CB 4.4Å; L34-L224 HydrophobicContact CD1-CD2 3.99Å; L34-L224 HydrophobicContact CD1-CG 3.93Å; L34-L224 HydrophobicContact CD2-CD2 4.41Å; L34-A225 HydrophobicContact CB-CB 3.82Å; L34-A225 HydrophobicContact CD1-CB 4.36Å; L34-I228 HydrophobicContact CD1-CD1 3.51Å
35	C	86.5	Confident	88.4	Confident	19 Å²	19	23.4 Å²	23.4	13%	0.128	13%	0.133	C	C	.	.	H	α-helix	trans	-69.8	-39.2	173	-67.9	0	0	0	0	112.2	F31 F32 Q33 F37 T38 L39 I172 A225	F31-C35 VanDerWaalsContact CE2-SG 3.53Å; F31-C35 PolarHBondContact O-N 2.82Å; F31-C35 VanDerWaalsContact O-N 3.11Å; F31-C35 PolarHBondContact O-SG 3.29Å; F32-C35 PolarHBondContact O-N 2.97Å; Q33-C35 VanDerWaalsContact C-N 3.28Å; Q33-C35 PolarHBondContact O-N 3.27Å; C35-F37 VanDerWaalsContact C-N 3.3Å; C35-F37 PolarHBondContact O-N 2.79Å; C35-T38 PolarHBondContact O-N 3.48Å; C35-L39 WeakPolarHBondContact O-CB 3.25Å; C35-L39 PolarHBondContact O-N 3.38Å; C35-I172 HydrophobicContact CB-CD1 3.37Å; C35-I172 HydrophobicContact CB-CG2 4.3Å; C35-I172 WeakPolarHBondContact SG-CD1 3.47Å; C35-A225 VanDerWaalsContact SG-CB 3.52Å
36	C	88	Confident	88.7	Confident	17 Å²	17	23.2 Å²	23.2	12%	0.115	13%	0.133	C	C	.	.	H	α-helix	trans	-61.5	-38.3	171.8	-72.9	0	0	0	0	111.9	F32 Q33 L39 A40	F32-C36 VanDerWaalsContact CZ-SG 3.56Å; F32-C36 PolarHBondContact O-N 3.32Å; F32-C36 PolarHBondContact O-SG 3.47Å; F32-C36 VanDerWaalsContact O-SG 3.33Å; Q33-C36 CarbonylContact O-C 3.58Å; Q33-C36 WeakPolarHBondContact O-CB 3.5Å; Q33-C36 PolarHBondContact O-N 2.98Å; Q33-C36 VanDerWaalsContact O-N 3.14Å; C36-L39 PolarHBondContact O-N 3.38Å; C36-A40 VanDerWaalsContact O-CB 3.25Å; C36-A40 WeakPolarHBondContact O-CB 3.33Å; C36-A40 PolarHBondContact O-N 3.1Å
37	F	91.2	Very high	88.9	Confident	35 Å²	35	18.9 Å²	18.9	15%	0.154	11%	0.106	C	C	.	.	H	α-helix	trans	-60.2	-49.5	173	-72.4	-10.1	0	0	0	111.7	Q33 L34 C35 L39 A40 A41 I196 G197 Y200 I221	Q33-F37 HydrophobicContact CG-CD1 4.27Å; Q33-F37 HydrophobicContact CG-CE1 3.91Å; Q33-F37 HydrophobicContact CG-CE2 4.13Å; Q33-F37 HydrophobicContact CG-CZ 3.8Å; Q33-F37 VanDerWaalsContact NE2-CD1 3.29Å; Q33-F37 WeakPolarHBondContact O-CG 3.5Å; Q33-F37 PolarHBondContact O-N 3.38Å; L34-F37 HydrophobicContact CD2-CD2 4.2Å; L34-F37 WeakPolarHBondContact O-CB 3.47Å; L34-F37 PolarHBondContact O-N 3.43Å; C35-F37 VanDerWaalsContact C-N 3.3Å; C35-F37 PolarHBondContact O-N 2.79Å; F37-L39 VanDerWaalsContact C-N 3.33Å; F37-L39 PolarHBondContact O-N 3.16Å; F37-A40 PolarHBondContact O-N 3.19Å; F37-A41 WeakPolarHBondContact O-CB 3.24Å; F37-A41 PolarHBondContact O-N 2.74Å; F37-I196 HydrophobicContact CE1-CB 4.31Å; F37-I196 HydrophobicContact CE1-CG2 3.73Å; F37-I196 HydrophobicContact CZ-CG2 4.05Å; F37-G197 VanDerWaalsContact CD1-CA 3.44Å; F37-Y200 HydrophobicContact CB-CD1 3.66Å; F37-Y200 HydrophobicContact CB-CE1 3.92Å; F37-Y200 HydrophobicContact CB-CG 4.17Å; F37-Y200 HydrophobicContact CD1-CD1 4.38Å; F37-Y200 HydrophobicContact CD1-CG 4.16Å; F37-Y200 HydrophobicContact CD2-CD1 4.34Å; F37-Y200 HydrophobicContact CD2-CD2 4.09Å; F37-Y200 HydrophobicContact CD2-CE2 4.43Å; F37-Y200 HydrophobicContact CD2-CG 4.04Å; F37-Y200 HydrophobicContact CE1-CG 4.4Å; F37-Y200 HydrophobicContact CE2-CD2 4.27Å; F37-Y200 HydrophobicContact CE2-CG 4.41Å; F37-Y200 AromaticContact CG-CD1 3.93Å; F37-Y200 HydrophobicContact CG-CD1 3.93Å; F37-Y200 HydrophobicContact CG-CD2 4.42Å; F37-Y200 HydrophobicContact CG-CE1 4.46Å; F37-Y200 AromaticContact CG-CG 3.9Å; F37-Y200 HydrophobicContact CG-CG 3.9Å; F37-I221 HydrophobicContact CB-CG2 4.41Å; F37-I221 HydrophobicContact CD2-CG1 4.5Å
38	T	89.2	Confident	89.1	Confident	12 Å²	12	17.4 Å²	17.4	7%	0.074	9%	0.093	C	C	.	.	H	α-helix	trans	-60.3	-44.2	178.2	-51.6	0	0	0	0	111.4	L34 C35 N42 L139 I221 G222	L34-T38 PolarHBondContact O-N 2.87Å; L34-T38 PolarHBondContact O-OG1 3.02Å; C35-T38 PolarHBondContact O-N 3.48Å; T38-N42 WeakPolarHBondContact O-CB 3.42Å; T38-N42 PolarHBondContact O-N 3.13Å; T38-N42 PolarHBondContact O-ND2 3.34Å; T38-L139 HydrophobicContact CG2-CD2 3.82Å; T38-I221 WeakPolarHBondContact OG1-CG2 3.19Å; T38-G222 WeakPolarHBondContact OG1-CA 3.45Å; T38-G222 PolarHBondContact OG1-N 3.21Å
39	L	87.1	Confident	89.5	Confident	45 Å²	45	17.4 Å²	17.4	24%	0.236	9%	0.093	C	C	.	.	H	α-helix	trans	-65	-47.8	179.3	-179.1	66.2	0	0	0	111.7	C35 C36 F37 N42 M43	C35-L39 WeakPolarHBondContact O-CB 3.25Å; C35-L39 PolarHBondContact O-N 3.38Å; C36-L39 PolarHBondContact O-N 3.38Å; F37-L39 VanDerWaalsContact C-N 3.33Å; F37-L39 PolarHBondContact O-N 3.16Å; L39-N42 PolarHBondContact O-N 3.33Å; L39-M43 WeakPolarHBondContact O-CB 3.34Å; L39-M43 PolarHBondContact O-N 3.14Å
40	A	90.3	Very high	89.7	Confident	0 Å²	0	15.1 Å²	15.1	0%	0	9%	0.085	C	C	.	.	H	α-helix	trans	-65.4	-40.9	179.8	0	0	0	0	0	112	C36 F37 M43 A44 F194 L198	C36-A40 VanDerWaalsContact O-CB 3.25Å; C36-A40 WeakPolarHBondContact O-CB 3.33Å; C36-A40 PolarHBondContact O-N 3.1Å; F37-A40 PolarHBondContact O-N 3.19Å; A40-M43 PolarHBondContact O-N 2.73Å; A40-A44 WeakPolarHBondContact O-CB 3.44Å; A40-A44 PolarHBondContact O-N 3.17Å; A40-F194 HydrophobicContact CB-CD2 3.83Å; A40-F194 HydrophobicContact CB-CE2 3.74Å; A40-F194 HydrophobicContact CB-CZ 4.33Å; A40-L198 HydrophobicContact CB-CD2 4.35Å; A40-L198 HydrophobicContact CB-CG 4.5Å
41	A	91.8	Very high	89.7	Confident	2 Å²	2	15.3 Å²	15.3	2%	0.017	8%	0.081	C	C	.	.	H	α-helix	trans	-65.5	-41.3	176.8	0	0	0	0	0	112.2	F37 M43 A44 Y45 Y200 A201	F37-A41 WeakPolarHBondContact O-CB 3.24Å; F37-A41 PolarHBondContact O-N 2.74Å; A41-M43 VanDerWaalsContact C-N 3.31Å; A41-M43 PolarHBondContact O-N 3.08Å; A41-A44 CarbonylContact O-C 3.58Å; A41-A44 PolarHBondContact O-N 2.95Å; A41-Y45 WeakPolarHBondContact O-CA 3.19Å; A41-Y45 WeakPolarHBondContact O-CB 3.45Å; A41-Y45 PolarHBondContact O-N 2.82Å; A41-Y200 HydrophobicContact CB-CD1 4.48Å; A41-Y200 HydrophobicContact CB-CE1 4.37Å; A41-A201 HydrophobicContact CB-CB 4Å
42	N	89.9	Confident	89.7	Confident	20 Å²	20	16.3 Å²	16.3	11%	0.107	9%	0.086	C	C	.	.	H	α-helix	trans	-65.4	-32.8	173.6	-83.4	-72.3	0	0	0	112.7	T38 L39 Y45 Q116 N219	T38-N42 WeakPolarHBondContact O-CB 3.42Å; T38-N42 PolarHBondContact O-N 3.13Å; T38-N42 PolarHBondContact O-ND2 3.34Å; L39-N42 PolarHBondContact O-N 3.33Å; N42-Y45 WeakPolarHBondContact O-CB 3.35Å; N42-Q116 PolarHBondContact O-NE2 3.01Å; N42-N219 PolarHBondContact ND2-OD1 3.16Å
43	M	87.2	Confident	89.8	Confident	34 Å²	34	16.2 Å²	16.2	17%	0.167	9%	0.086	C	C	.	.	H	α-helix	trans	-73.4	-41.2	176.1	-170.9	168.1	177.8	0	0	112	L39 A40 A41 Y45 F194 T316 L319 Y320	L39-M43 WeakPolarHBondContact O-CB 3.34Å; L39-M43 PolarHBondContact O-N 3.14Å; A40-M43 PolarHBondContact O-N 2.73Å; A41-M43 VanDerWaalsContact C-N 3.31Å; A41-M43 PolarHBondContact O-N 3.08Å; M43-Y45 VanDerWaalsContact C-N 3.28Å; M43-Y45 PolarHBondContact O-N 3.28Å; M43-F194 HydrophobicContact CB-CE2 4.43Å; M43-F194 HydrophobicContact CB-CZ 4.36Å; M43-F194 HydrophobicContact CG-CZ 4.32Å; M43-F194 HydrophobicContact SD-CE1 4.47Å; M43-F194 HydrophobicContact SD-CE2 3.84Å; M43-F194 HydrophobicContact SD-CZ 3.42Å; M43-F194 WeakPolarHBondContact SD-CZ 3.3Å; M43-T316 HydrophobicContact CE-CG2 3.99Å; M43-T316 WeakPolarHBondContact CE-OG1 3.41Å; M43-L319 HydrophobicContact CG-CD2 4.3Å; M43-Y320 PolarHBondContact O-OH 3.06Å
44	A	91.3	Very high	89.7	Confident	4 Å²	4	22.3 Å²	22.3	3%	0.033	11%	0.112	C	C	.	.	H	α-helix	trans	-77.7	-10.4	175.6	0	0	0	0	0	113.2	A40 A41 M46 L47 Y48 L198 A201	A40-A44 WeakPolarHBondContact O-CB 3.44Å; A40-A44 PolarHBondContact O-N 3.17Å; A41-A44 CarbonylContact O-C 3.58Å; A41-A44 PolarHBondContact O-N 2.95Å; A44-M46 PolarHBondContact O-N 2.66Å; A44-L47 WeakPolarHBondContact O-CB 3.49Å; A44-L47 PolarHBondContact O-N 2.98Å; A44-Y48 WeakPolarHBondContact O-CD2 3.44Å; A44-L198 HydrophobicContact CB-CD2 4.19Å; A44-A201 HydrophobicContact CB-CB 3.91Å
45	Y	92.2	Very high	89.6	Confident	4 Å²	4	21.8 Å²	21.8	2%	0.016	11%	0.109	C	C	.	.	H	α-helix	trans	-53.9	-50.3	-176.1	172.9	-110.1	0	0	0	112.5	A41 N42 M43 L47 Y48 A49 I95 M158 L214 V215	A41-Y45 WeakPolarHBondContact O-CA 3.19Å; A41-Y45 WeakPolarHBondContact O-CB 3.45Å; A41-Y45 PolarHBondContact O-N 2.82Å; N42-Y45 WeakPolarHBondContact O-CB 3.35Å; M43-Y45 VanDerWaalsContact C-N 3.28Å; M43-Y45 PolarHBondContact O-N 3.28Å; Y45-L47 PolarHBondContact O-N 3.31Å; Y45-Y48 PolarHBondContact O-N 3.12Å; Y45-Y48 VanDerWaalsContact O-N 3.13Å; Y45-A49 HydrophobicContact CD1-CB 4.16Å; Y45-A49 HydrophobicContact CD2-CB 4.06Å; Y45-A49 HydrophobicContact CE1-CB 3.73Å; Y45-A49 HydrophobicContact CE2-CB 3.61Å; Y45-A49 HydrophobicContact CG-CB 4.31Å; Y45-A49 VanDerWaalsContact CZ-CB 3.44Å; Y45-A49 VanDerWaalsContact O-CB 3.3Å; Y45-A49 WeakPolarHBondContact O-CB 3.37Å; Y45-A49 PolarHBondContact O-N 3.47Å; Y45-I95 HydrophobicContact CE1-CD1 4.28Å; Y45-M158 HydrophobicContact CD1-CE 4.1Å; Y45-M158 HydrophobicContact CE1-CE 4.21Å; Y45-M158 HydrophobicContact CE1-SD 4.18Å; Y45-L214 HydrophobicContact CD2-CD2 3.9Å; Y45-L214 HydrophobicContact CD2-CG 4.03Å; Y45-L214 HydrophobicContact CE2-CD2 4.36Å; Y45-L214 HydrophobicContact CE2-CG 4.43Å; Y45-V215 HydrophobicContact CD2-CB 4.25Å; Y45-V215 HydrophobicContact CE2-CB 3.67Å; Y45-V215 HydrophobicContact CE2-CG2 4.39Å
46	M	91	Very high	89.6	Confident	5 Å²	5	21.6 Å²	21.6	3%	0.025	11%	0.107	C	C	.	.	H	α-helix	trans	-72.7	-13.7	-177.8	-68.8	-60.5	-73.5	0	0	114	A44 Y48 A49 G50 I95 I109 M112 M113 M158 Y320	A44-M46 PolarHBondContact O-N 2.66Å; M46-Y48 VanDerWaalsContact C-N 3.27Å; M46-A49 HydrophobicContact SD-CB 4.35Å; M46-G50 WeakPolarHBondContact O-CA 3.33Å; M46-G50 PolarHBondContact O-N 3.48Å; M46-G50 VanDerWaalsContact O-N 3.08Å; M46-I95 HydrophobicContact SD-CD1 4.34Å; M46-I109 HydrophobicContact CE-CG2 3.62Å; M46-M112 HydrophobicContact CE-CB 4.3Å; M46-M113 HydrophobicContact CB-CE 4.19Å; M46-M113 HydrophobicContact CB-CG 3.71Å; M46-M113 HydrophobicContact CB-SD 4.14Å; M46-M113 HydrophobicContact CE-CG 3.59Å; M46-M113 HydrophobicContact CE-SD 4.39Å; M46-M113 HydrophobicContact CG-CG 3.66Å; M46-M113 HydrophobicContact SD-CG 4.46Å; M46-M158 HydrophobicContact CG-CE 3.65Å; M46-M158 HydrophobicContact SD-CE 3.65Å; M46-M158 HydrophobicContact SD-SD 4.39Å; M46-Y320 HydrophobicContact CB-CE1 4.22Å
47	L	91.1	Very high	89.5	Confident	9 Å²	9	21 Å²	21	5%	0.047	10%	0.104	C	C	.	.	H	α-helix	trans	-63.2	-38.4	169.5	172.7	63.5	0	0	0	110.5	A44 Y45 L319 Y320 L322 I329	A44-L47 WeakPolarHBondContact O-CB 3.49Å; A44-L47 PolarHBondContact O-N 2.98Å; Y45-L47 PolarHBondContact O-N 3.31Å; L47-L319 HydrophobicContact CD2-CD1 4.26Å; L47-Y320 HydrophobicContact CB-CD1 4.17Å; L47-Y320 HydrophobicContact CB-CE1 4.24Å; L47-L322 HydrophobicContact CD1-CB 4.08Å; L47-L322 HydrophobicContact CD2-CB 4.38Å; L47-L322 HydrophobicContact CD2-CD1 4.21Å; L47-I329 HydrophobicContact CD1-CD1 4.34Å; L47-I329 HydrophobicContact CG-CD1 4.27Å
48	Y	93.2	Very high	89.1	Confident	3 Å²	3	21.9 Å²	21.9	1%	0.012	11%	0.108	C	C	.	.	H	α-helix	trans	-94.5	-51.9	179	-59.1	-80.2	0	0	0	111.8	A44 Y45 M46 G50 L51 F92 V202 A205 L214 I329 Y330 S333	A44-Y48 WeakPolarHBondContact O-CD2 3.44Å; Y45-Y48 PolarHBondContact O-N 3.12Å; Y45-Y48 VanDerWaalsContact O-N 3.13Å; M46-Y48 VanDerWaalsContact C-N 3.27Å; Y48-G50 VanDerWaalsContact C-N 3.26Å; Y48-G50 PolarHBondContact O-N 3Å; Y48-L51 VanDerWaalsContact O-CB 3.26Å; Y48-L51 WeakPolarHBondContact O-CB 3.38Å; Y48-L51 PolarHBondContact O-N 3.49Å; Y48-L51 VanDerWaalsContact O-N 3.11Å; Y48-F92 WeakPolarHBondContact O-CD1 3.3Å; Y48-V202 WeakPolarHBondContact OH-CG2 3.43Å; Y48-A205 HydrophobicContact CD1-CB 3.97Å; Y48-A205 HydrophobicContact CD2-CB 3.81Å; Y48-A205 HydrophobicContact CE1-CB 3.89Å; Y48-A205 HydrophobicContact CE2-CB 3.73Å; Y48-A205 HydrophobicContact CG-CB 3.93Å; Y48-L214 HydrophobicContact CD2-CD2 4.22Å; Y48-L214 HydrophobicContact CG-CD2 4.37Å; Y48-I329 HydrophobicContact CD1-CD1 3.97Å; Y48-I329 HydrophobicContact CD1-CG1 4.43Å; Y48-I329 HydrophobicContact CE1-CD1 4.1Å; Y48-I329 HydrophobicContact CE1-CG1 4.07Å; Y48-I329 HydrophobicContact CE1-CG2 4.38Å; Y48-Y330 HydrophobicContact CD1-CE1 4.34Å; Y48-Y330 AromaticContact CE1-CD1 4Å; Y48-Y330 HydrophobicContact CE1-CD1 4Å; Y48-Y330 HydrophobicContact CE1-CE1 4.01Å; Y48-S333 VanDerWaalsContact OH-CB 3.27Å; Y48-S333 WeakPolarHBondContact OH-CB 3.15Å; Y48-S333 PolarHBondContact OH-OG 3.34Å
49	A	92.3	Very high	88.7	Confident	0 Å²	0	22.1 Å²	22.1	0%	0	11%	0.109	C	C	.	.	H	α-helix	trans	-66.6	-29.3	-175.2	0	0	0	0	0	113	Y45 M46 P94 I95 W211	Y45-A49 HydrophobicContact CD1-CB 4.16Å; Y45-A49 HydrophobicContact CD2-CB 4.06Å; Y45-A49 HydrophobicContact CE1-CB 3.73Å; Y45-A49 HydrophobicContact CE2-CB 3.61Å; Y45-A49 HydrophobicContact CG-CB 4.31Å; Y45-A49 VanDerWaalsContact CZ-CB 3.44Å; Y45-A49 VanDerWaalsContact O-CB 3.3Å; Y45-A49 WeakPolarHBondContact O-CB 3.37Å; Y45-A49 PolarHBondContact O-N 3.47Å; M46-A49 HydrophobicContact SD-CB 4.35Å; A49-P94 WeakPolarHBondContact O-CB 3.26Å; A49-I95 HydrophobicContact CB-CD1 3.72Å; A49-I95 HydrophobicContact CB-CG1 4.03Å; A49-I95 WeakPolarHBondContact O-CB 3.21Å; A49-I95 PolarHBondContact O-N 3.1Å; A49-W211 HydrophobicContact CB-CB 3.89Å
50	G	90	Very high	88.1	Confident	3 Å²	3	28 Å²	28	3%	0.031	14%	0.136	C	C	.	.	T	Hydrogen-bonded Turn	trans	-90.1	0.3	175.6	0	0	0	0	0	114.3	M46 Y48 E52 R106	M46-G50 WeakPolarHBondContact O-CA 3.33Å; M46-G50 PolarHBondContact O-N 3.48Å; M46-G50 VanDerWaalsContact O-N 3.08Å; Y48-G50 VanDerWaalsContact C-N 3.26Å; Y48-G50 PolarHBondContact O-N 3Å; G50-E52 PolarHBondContact O-N 3.04Å; G50-R106 PolarHBondContact O-NH1 2.72Å; G50-R106 PolarHBondContact O-NH2 3.42Å
51	L	88.9	Confident	87.3	Confident	39 Å²	39	35.3 Å²	35.3	20%	0.204	18%	0.175	C	C	.	.			trans	-60.2	137	-178	-171.1	66.7	0	0	0	110.9	Y48 P53 P94 V96 I329	Y48-L51 VanDerWaalsContact O-CB 3.26Å; Y48-L51 WeakPolarHBondContact O-CB 3.38Å; Y48-L51 PolarHBondContact O-N 3.49Å; Y48-L51 VanDerWaalsContact O-N 3.11Å; L51-P53 WeakPolarHBondContact O-CD 3.32Å; L51-P94 HydrophobicContact CB-CB 4.45Å; L51-P94 WeakPolarHBondContact O-CB 2.91Å; L51-P94 WeakPolarHBondContact O-CG 3.06Å; L51-V96 WeakPolarHBondContact O-CG2 3.35Å; L51-I329 HydrophobicContact CD1-CD1 4.18Å; L51-I329 HydrophobicContact CD2-CD1 4.07Å
52	E	88.3	Confident	86	Confident	38 Å²	38	38 Å²	38	18%	0.178	20%	0.203	C	C	.	.			trans	-101.1	102.6	170.4	-170.1	171.6	170.1	0	0	108.1	G50 W55 V96 R106 R448	G50-E52 PolarHBondContact O-N 3.04Å; E52-W55 PolarHBondContact OE1-NE1 3.45Å; E52-V96 HydrophobicContact CG-CG1 4.38Å; E52-R106 IonicContact OE2-CZ 3.69Å; E52-R106 IonicContact OE2-NE 3.9Å; E52-R106 PolarHBondContact OE2-NE 2.61Å; E52-R448 IonicContact OE2-CZ 3.99Å; E52-R448 IonicContact OE2-NH1 2.66Å; E52-R448 IonicContact OE2-NH2 3.04Å; E52-R448 PolarHBondContact OE2-NH2 2.7Å
53	P	87.7	Confident	84.9	Confident	9 Å²	9	39.2 Å²	39.2	6%	0.058	21%	0.213	C	C	.	.			trans	-62.6	157.3	170.6	-15.5	30.1	0	0	0	109.7	L51 W55 W87 V90 P94 V97	L51-P53 WeakPolarHBondContact O-CD 3.32Å; P53-W55 PolarHBondContact O-N 2.76Å; P53-W87 HydrophobicContact CB-CE3 4.12Å; P53-W87 HydrophobicContact CG-CE3 4.23Å; P53-V90 HydrophobicContact CB-CG2 3.99Å; P53-V90 HydrophobicContact CG-CG2 4.16Å; P53-P94 HydrophobicContact CG-CG 3.92Å; P53-V97 HydrophobicContact CG-CG2 3.89Å
54	K	86.4	Confident	83.8	Confident	148 Å²	148	41.4 Å²	41.4	64%	0.643	23%	0.225	S	C	*	.	E	Extended strand (participates in β ladder)	trans	-61.7	139.5	171.3	-68.4	178	-176.5	170	0	108.7	H88	K54-H88 HydrophobicContact CB-CB 4.22Å; K54-H88 PolarHBondContact O-N 2.86Å
55	W	88.7	Confident	82.3	Confident	11 Å²	11	47.8 Å²	47.8	4%	0.042	25%	0.249	C	C	.	.	E	Extended strand (participates in β ladder)	trans	-138.9	154.2	179.6	60.3	-86.1	0	0	0	110.4	E52 P53 C57 L70 Q73 F77 I85 T86 W87 I102	E52-W55 PolarHBondContact OE1-NE1 3.45Å; P53-W55 PolarHBondContact O-N 2.76Å; W55-C57 HydrophobicContact CZ3-CB 4.11Å; W55-L70 HydrophobicContact CZ2-CD1 4.09Å; W55-Q73 HydrophobicContact CH2-CB 3.84Å; W55-Q73 HydrophobicContact CZ2-CB 4.45Å; W55-Q73 HydrophobicContact CZ3-CB 4.15Å; W55-Q73 PolarHBondContact O-OE1 3.44Å; W55-F77 HydrophobicContact CH2-CB 4.36Å; W55-I85 HydrophobicContact CB-CG2 3.98Å; W55-I85 HydrophobicContact CE3-CG2 4.15Å; W55-T86 CarbonylContact C-O 3.56Å; W55-T86 VanDerWaalsContact CA-O 3.24Å; W55-T86 WeakPolarHBondContact CA-O 3.19Å; W55-W87 HydrophobicContact CB-CD2 4.2Å; W55-W87 HydrophobicContact CB-CE3 3.61Å; W55-W87 HydrophobicContact CB-CZ3 3.78Å; W55-W87 AromaticContact CD1-CZ3 3.83Å; W55-W87 HydrophobicContact CG-CE3 4.3Å; W55-W87 AromaticContact CG-CZ3 3.96Å; W55-W87 HydrophobicContact CG-CZ3 3.96Å; W55-I102 HydrophobicContact CD2-CD1 4.19Å; W55-I102 HydrophobicContact CE3-CD1 4.2Å; W55-I102 HydrophobicContact CH2-CD1 3.85Å; W55-I102 HydrophobicContact CZ2-CB 4.37Å; W55-I102 HydrophobicContact CZ2-CD1 3.84Å; W55-I102 HydrophobicContact CZ3-CD1 4.02Å
56	T	86.8	Confident	80.8	Confident	15 Å²	15	51.9 Å²	51.9	9%	0.092	27%	0.274	C	S	.	.	E	Extended strand (participates in β ladder)	trans	-127.3	145.1	172.9	41.8	0	0	0	0	109.4	T86 H88	T56-T86 PolarHBondContact N-O 3.35Å; T56-T86 PolarHBondContact O-N 2.87Å; T56-T86 PolarHBondContact O-OG1 2.85Å; T56-T86 PolarHBondContact OG1-OG1 3.1Å; T56-H88 PolarHBondContact OG1-NE2 3.23Å
57	C	84.8	Confident	79.5	Confident	6 Å²	6	59.3 Å²	59.3	4%	0.041	31%	0.314	C	S	.	.	E	Extended strand (participates in β ladder)	trans	-98.9	122.5	177	174.9	0	0	0	0	109.6	W55 C82	W55-C57 HydrophobicContact CZ3-CB 4.11Å; C57-C82 WeakPolarHBondContact CA-SG 3.42Å; C57-C82 HydrophobicContact CB-CB 4.37Å; C57-C82 WeakPolarHBondContact CB-SG 3.49Å; C57-C82 WeakPolarHBondContact SG-CA 3.4Å; C57-C82 WeakPolarHBondContact SG-CB 3.1Å; C57-C82 CovalentContact SG-SG 2.02Å; C57-C82 PolarHBondContact SG-SG 2.93Å
58	E	83.3	Confident	78.6	Confident	53 Å²	53	60.6 Å²	60.6	25%	0.248	32%	0.322	C	S	.	.	E	Extended strand (participates in β ladder)	trans	-84.3	130.8	168.5	-75	174.7	179.1	0	0	109.3	N64 C82 S83 N84 T86	E58-N64 WeakPolarHBondContact CG-OD1 3.38Å; E58-N64 PolarHBondContact OE1-ND2 3.29Å; E58-C82 CarbonylContact O-C 3.58Å; E58-C82 WeakPolarHBondContact O-CA 3.48Å; E58-S83 PolarHBondContact O-N 3.47Å; E58-S83 PolarHBondContact O-OG 2.92Å; E58-N84 HydrophobicContact CB-CB 4.4Å; E58-N84 PolarHBondContact N-O 2.86Å; E58-T86 WeakPolarHBondContact OE1-CG2 3.1Å
59	T	80.6	Confident	78	Confident	16 Å²	16	63.1 Å²	63.1	10%	0.098	34%	0.34	C	S	.	.	E	Extended strand (participates in β ladder)	trans	-91.5	159.2	171.9	56.3	0	0	0	0	110.4	D61 G62 S63	T59-D61 PolarHBondContact O-N 2.79Å; T59-D61 VanDerWaalsContact O-N 3.12Å; T59-G62 PolarHBondContact O-N 3.34Å; T59-S63 PolarHBondContact OG1-O 3.17Å; T59-S63 PolarHBondContact OG1-OG 3.04Å
60	E	73.6	Confident	77.4	Confident	169 Å²	169	67.4 Å²	67.4	79%	0.79	36%	0.363	S	S	*	.	T	Hydrogen-bonded Turn	trans	-53.4	-33.1	177.3	-66.5	-176.1	162.7	0	0	113.9	G62	E60-G62 PolarHBondContact O-N 2.71Å
61	D	73.7	Confident	77.1	Confident	153 Å²	153	73.4 Å²	73.4	82%	0.818	39%	0.39	S	S	*	.	T	Hydrogen-bonded Turn	trans	-69.6	4	176.5	-61.6	-29.4	0	0	0	114.2	T59 S63	T59-D61 PolarHBondContact O-N 2.79Å; T59-D61 VanDerWaalsContact O-N 3.12Å; D61-S63 PolarHBondContact O-N 2.68Å; D61-S63 VanDerWaalsContact O-N 3.12Å
62	G	64.9	Low	76.9	Confident	60 Å²	60	74.8 Å²	74.8	62%	0.619	40%	0.398	S	S	*	.			trans	69.6	3.3	-176	0	0	0	0	0	114.4	T59 E60 N64	T59-G62 PolarHBondContact O-N 3.34Å; E60-G62 PolarHBondContact O-N 2.71Å; G62-N64 PolarHBondContact O-N 3.48Å; G62-N64 VanDerWaalsContact O-N 3.16Å
63	S	67.5	Low	76.7	Confident	45 Å²	45	73.8 Å²	73.8	32%	0.315	39%	0.393	S	S	.	.			trans	-73.5	107.2	179.4	80.7	0	0	0	0	111.1	T59 D61 R65	T59-S63 PolarHBondContact OG1-O 3.17Å; T59-S63 PolarHBondContact OG1-OG 3.04Å; D61-S63 PolarHBondContact O-N 2.68Å; D61-S63 VanDerWaalsContact O-N 3.12Å; S63-R65 PolarHBondContact O-N 3.37Å; S63-R65 VanDerWaalsContact O-N 3.1Å
64	N	63.2	Low	76.8	Confident	79 Å²	79	74.4 Å²	74.4	42%	0.422	40%	0.397	S	S	.	.	B	Isolated β-bridge	trans	-76.5	93.7	169.1	-103.4	-34.2	0	0	0	108.8	E58 G62 T66	E58-N64 WeakPolarHBondContact CG-OD1 3.38Å; E58-N64 PolarHBondContact OE1-ND2 3.29Å; G62-N64 PolarHBondContact O-N 3.48Å; G62-N64 VanDerWaalsContact O-N 3.16Å; N64-T66 VanDerWaalsContact C-N 3.27Å; N64-T66 PolarHBondContact O-N 2.84Å
65	R	61.5	Low	76.8	Confident	139 Å²	139	72.4 Å²	72.4	53%	0.525	39%	0.388	S	S	.	.			trans	-79.4	77.3	177.1	-64.6	-166.4	-179.3	-168.5	-0.6	110.6	S63 N67 V68	S63-R65 PolarHBondContact O-N 3.37Å; S63-R65 VanDerWaalsContact O-N 3.1Å; R65-N67 VanDerWaalsContact C-N 3.34Å; R65-N67 PolarHBondContact O-N 3.24Å; R65-V68 HydrophobicContact CB-CB 4.32Å; R65-V68 HydrophobicContact CB-CG2 3.52Å; R65-V68 HydrophobicContact CG-CG2 4.3Å
66	T	59.4	Low	76.7	Confident	90 Å²	90	73.2 Å²	73.2	55%	0.552	39%	0.393	S	S	*	.	T	Hydrogen-bonded Turn	trans	-70.5	-26.5	-179	51.8	0	0	0	0	113.7	N64 V68	N64-T66 VanDerWaalsContact C-N 3.27Å; N64-T66 PolarHBondContact O-N 2.84Å; T66-V68 VanDerWaalsContact C-N 3.34Å; T66-V68 PolarHBondContact O-N 3.14Å
67	N	64.3	Low	76.7	Confident	160 Å²	160	75.3 Å²	75.3	86%	0.856	40%	0.401	S	S	*	.	T	Hydrogen-bonded Turn	trans	-95	21.7	-175.9	-69.8	-13.9	0	0	0	114.1	R65	R65-N67 VanDerWaalsContact C-N 3.34Å; R65-N67 PolarHBondContact O-N 3.24Å
68	V	71.9	Confident	76.8	Confident	37 Å²	37	79.9 Å²	79.9	22%	0.224	42%	0.422	C	S	.	.	S	Bend	trans	-94.2	141.7	-177.6	172.8	0	0	0	0	110	R65 T66 D72 Q73	R65-V68 HydrophobicContact CB-CB 4.32Å; R65-V68 HydrophobicContact CB-CG2 3.52Å; R65-V68 HydrophobicContact CG-CG2 4.3Å; T66-V68 VanDerWaalsContact C-N 3.34Å; T66-V68 PolarHBondContact O-N 3.14Å; V68-D72 HydrophobicContact CG1-CB 3.16Å; V68-Q73 HydrophobicContact CB-CG 4.26Å; V68-Q73 HydrophobicContact CG1-CG 4.01Å
69	S	80	Confident	77	Confident	56 Å²	56	80.6 Å²	80.6	39%	0.392	43%	0.433	S	S	.	.			trans	-60	150.2	176.5	78.7	0	0	0	0	110.4	E71 D72 Q73	S69-E71 PolarHBondContact O-N 3.29Å; S69-E71 VanDerWaalsContact O-N 3.13Å; S69-D72 PolarHBondContact O-N 3.29Å; S69-D72 WeakPolarHBondContact OG-CB 3.35Å; S69-D72 PolarHBondContact OG-N 3.31Å; S69-D72 PolarHBondContact OG-OD2 3.49Å; S69-Q73 PolarHBondContact O-N 2.65Å
70	L	81.1	Confident	77.3	Confident	90 Å²	90	82.6 Å²	82.6	47%	0.471	46%	0.457	S	S	.	.	H	α-helix	trans	-55	-33.8	176.8	-177.5	69	0	0	0	111.7	W55 Q73 C74	W55-L70 HydrophobicContact CZ2-CD1 4.09Å; L70-Q73 PolarHBondContact O-N 3Å; L70-C74 WeakPolarHBondContact O-CB 3.38Å; L70-C74 PolarHBondContact O-N 2.85Å; L70-C74 PolarHBondContact O-SG 2.88Å
71	E	82.5	Confident	77.8	Confident	128 Å²	128	82.8 Å²	82.8	60%	0.598	45%	0.45	S	S	*	.	H	α-helix	trans	-66.4	-41.6	179	-162.9	-175.6	141.8	0	0	112	S69 C74 K75	S69-E71 PolarHBondContact O-N 3.29Å; S69-E71 VanDerWaalsContact O-N 3.13Å; E71-C74 WeakPolarHBondContact O-CB 3.23Å; E71-C74 PolarHBondContact O-N 3.18Å; E71-K75 WeakPolarHBondContact O-CG 2.98Å; E71-K75 PolarHBondContact O-N 3.49Å; E71-K75 WeakPolarHBondContact OE1-CE 3.14Å; E71-K75 IonicContact OE1-NZ 3.62Å; E71-K75 PolarHBondContact OE1-NZ 3.43Å
72	D	84.1	Confident	78.3	Confident	69 Å²	69	76.7 Å²	76.7	37%	0.369	42%	0.419	S	S	.	.	H	α-helix	trans	-72.4	-35.7	177.5	-65	-37.2	0	0	0	111.9	V68 S69 C74 K75 L76	V68-D72 HydrophobicContact CG1-CB 3.16Å; S69-D72 PolarHBondContact O-N 3.29Å; S69-D72 WeakPolarHBondContact OG-CB 3.35Å; S69-D72 PolarHBondContact OG-N 3.31Å; S69-D72 PolarHBondContact OG-OD2 3.49Å; D72-C74 VanDerWaalsContact C-N 3.29Å; D72-C74 PolarHBondContact O-N 3.49Å; D72-K75 PolarHBondContact O-N 2.83Å; D72-K75 IonicContact OD1-NZ 2.73Å; D72-L76 WeakPolarHBondContact O-CG 3.37Å; D72-L76 PolarHBondContact O-N 3.02Å
73	Q	85.5	Confident	79.2	Confident	17 Å²	17	77.3 Å²	77.3	8%	0.079	41%	0.414	C	S	.	.	H	α-helix	trans	-59.9	-42.2	170	-70.4	-177.4	-17.9	0	0	111	W55 V68 S69 L70 L76 F77	W55-Q73 HydrophobicContact CH2-CB 3.84Å; W55-Q73 HydrophobicContact CZ2-CB 4.45Å; W55-Q73 HydrophobicContact CZ3-CB 4.15Å; W55-Q73 PolarHBondContact O-OE1 3.44Å; V68-Q73 HydrophobicContact CB-CG 4.26Å; V68-Q73 HydrophobicContact CG1-CG 4.01Å; S69-Q73 PolarHBondContact O-N 2.65Å; L70-Q73 PolarHBondContact O-N 3Å; Q73-L76 PolarHBondContact O-N 3.3Å; Q73-F77 WeakPolarHBondContact O-CB 3.39Å; Q73-F77 PolarHBondContact O-N 2.98Å
74	C	88.3	Confident	80	Confident	21 Å²	21	79.5 Å²	79.5	14%	0.142	42%	0.422	C	S	.	.	H	α-helix	trans	-65	-41.4	175.4	-80.4	0	0	0	0	112.9	L70 E71 D72 L76 F77 E78 C103	L70-C74 WeakPolarHBondContact O-CB 3.38Å; L70-C74 PolarHBondContact O-N 2.85Å; L70-C74 PolarHBondContact O-SG 2.88Å; E71-C74 WeakPolarHBondContact O-CB 3.23Å; E71-C74 PolarHBondContact O-N 3.18Å; D72-C74 VanDerWaalsContact C-N 3.29Å; D72-C74 PolarHBondContact O-N 3.49Å; C74-L76 VanDerWaalsContact C-N 3.32Å; C74-L76 PolarHBondContact O-N 2.91Å; C74-F77 PolarHBondContact O-N 3.37Å; C74-E78 WeakPolarHBondContact O-CB 3.36Å; C74-E78 WeakPolarHBondContact O-CG 3.23Å; C74-E78 PolarHBondContact O-N 2.76Å; C74-C103 WeakPolarHBondContact CA-SG 3.25Å; C74-C103 HydrophobicContact CB-CB 3.66Å; C74-C103 WeakPolarHBondContact CB-SG 3.42Å; C74-C103 VanDerWaalsContact SG-CA 3.54Å; C74-C103 WeakPolarHBondContact SG-CB 3.26Å; C74-C103 CovalentContact SG-SG 2.04Å; C74-C103 PolarHBondContact SG-SG 3Å
75	K	87.4	Confident	81.2	Confident	107 Å²	107	77.5 Å²	77.5	47%	0.465	41%	0.411	S	S	.	.	H	α-helix	trans	-60.3	-42.1	174.6	-72.8	169	-172.6	158.6	0	111.7	E71 D72 S79	E71-K75 WeakPolarHBondContact O-CG 2.98Å; E71-K75 PolarHBondContact O-N 3.49Å; E71-K75 WeakPolarHBondContact OE1-CE 3.14Å; E71-K75 IonicContact OE1-NZ 3.62Å; E71-K75 PolarHBondContact OE1-NZ 3.43Å; D72-K75 PolarHBondContact O-N 2.83Å; D72-K75 IonicContact OD1-NZ 2.73Å; K75-S79 VanDerWaalsContact O-CB 3.23Å; K75-S79 WeakPolarHBondContact O-CB 3.37Å; K75-S79 PolarHBondContact O-N 3.12Å; K75-S79 PolarHBondContact O-OG 3.25Å; K75-S79 VanDerWaalsContact O-OG 3.12Å
76	L	85.7	Confident	82.4	Confident	27 Å²	27	72.6 Å²	72.6	14%	0.141	40%	0.397	C	S	.	.	H	α-helix	trans	-62.9	-47.5	176	-73.4	168.4	0	0	0	111.8	D72 Q73 C74 S79 G80 R81	D72-L76 WeakPolarHBondContact O-CG 3.37Å; D72-L76 PolarHBondContact O-N 3.02Å; Q73-L76 PolarHBondContact O-N 3.3Å; C74-L76 VanDerWaalsContact C-N 3.32Å; C74-L76 PolarHBondContact O-N 2.91Å; L76-S79 PolarHBondContact O-N 2.97Å; L76-S79 PolarHBondContact O-OG 3.34Å; L76-G80 PolarHBondContact O-N 3.18Å; L76-R81 HydrophobicContact CD2-CB 4.33Å; L76-R81 PolarHBondContact O-N 2.82Å
77	F	87.3	Confident	83.7	Confident	59 Å²	59	71.3 Å²	71.3	26%	0.259	38%	0.382	S	S	.	.	H	α-helix	trans	-60	-48.7	177.2	178	-108.8	0	0	0	112.5	W55 Q73 C74 S79 G80 C82 I85 I102	W55-F77 HydrophobicContact CH2-CB 4.36Å; Q73-F77 WeakPolarHBondContact O-CB 3.39Å; Q73-F77 PolarHBondContact O-N 2.98Å; C74-F77 PolarHBondContact O-N 3.37Å; F77-S79 VanDerWaalsContact C-N 3.3Å; F77-S79 PolarHBondContact O-N 3.2Å; F77-G80 PolarHBondContact O-N 3.09Å; F77-G80 VanDerWaalsContact O-N 3.15Å; F77-C82 HydrophobicContact CB-CB 4.45Å; F77-C82 HydrophobicContact CD2-CB 4.13Å; F77-I85 HydrophobicContact CD2-CD1 3.89Å; F77-I85 HydrophobicContact CD2-CG1 4.43Å; F77-I85 HydrophobicContact CE2-CD1 3.51Å; F77-I85 HydrophobicContact CE2-CG1 4.43Å; F77-I85 HydrophobicContact CZ-CD1 4.25Å; F77-I102 HydrophobicContact CD1-CD1 3.91Å; F77-I102 HydrophobicContact CD1-CG1 4Å; F77-I102 HydrophobicContact CD2-CD1 4.23Å; F77-I102 HydrophobicContact CE1-CD1 3.84Å; F77-I102 HydrophobicContact CE1-CG1 3.67Å; F77-I102 HydrophobicContact CE2-CD1 4.21Å; F77-I102 HydrophobicContact CG-CD1 4.09Å; F77-I102 HydrophobicContact CZ-CD1 3.99Å; F77-I102 HydrophobicContact CZ-CG1 4.11Å
78	E	87.7	Confident	84.7	Confident	103 Å²	103	67.5 Å²	67.5	48%	0.481	36%	0.359	S	S	.	.	H	α-helix	trans	-69.4	-27.7	-179	-69.3	179.8	168.4	0	0	112.8	C74 G80 C103 S104	C74-E78 WeakPolarHBondContact O-CB 3.36Å; C74-E78 WeakPolarHBondContact O-CG 3.23Å; C74-E78 PolarHBondContact O-N 2.76Å; E78-G80 PolarHBondContact O-N 3.41Å; E78-C103 HydrophobicContact CG-CB 4.42Å; E78-C103 WeakPolarHBondContact OE1-CB 3.46Å; E78-S104 WeakPolarHBondContact OE1-CB 3.41Å; E78-S104 PolarHBondContact OE1-N 3.4Å; E78-S104 PolarHBondContact OE1-OG 2.94Å
79	S	87.8	Confident	85	Confident	67 Å²	67	71.7 Å²	71.7	47%	0.469	38%	0.38	S	S	.	.	T	Hydrogen-bonded Turn	trans	-75.8	-4.4	173.9	72	0	0	0	0	114.5	K75 L76 F77 R81	K75-S79 VanDerWaalsContact O-CB 3.23Å; K75-S79 WeakPolarHBondContact O-CB 3.37Å; K75-S79 PolarHBondContact O-N 3.12Å; K75-S79 PolarHBondContact O-OG 3.25Å; K75-S79 VanDerWaalsContact O-OG 3.12Å; L76-S79 PolarHBondContact O-N 2.97Å; L76-S79 PolarHBondContact O-OG 3.34Å; F77-S79 VanDerWaalsContact C-N 3.3Å; F77-S79 PolarHBondContact O-N 3.2Å; S79-R81 PolarHBondContact O-N 3.46Å; S79-R81 WeakPolarHBondContact OG-CG 3.47Å
80	G	85.1	Confident	85	Confident	59 Å²	59	71.8 Å²	71.8	61%	0.608	38%	0.378	S	S	*	.	T	Hydrogen-bonded Turn	trans	74.7	7.8	-177.4	0	0	0	0	0	114.7	L76 F77 E78 C82	L76-G80 PolarHBondContact O-N 3.18Å; F77-G80 PolarHBondContact O-N 3.09Å; F77-G80 VanDerWaalsContact O-N 3.15Å; E78-G80 PolarHBondContact O-N 3.41Å; G80-C82 PolarHBondContact O-N 2.92Å
81	R	85	Confident	85	Confident	173 Å²	173	70.5 Å²	70.5	65%	0.653	38%	0.377	S	S	*	.			trans	-81.6	1.4	178	-65.4	179.7	-179.7	-173	-0.2	113.7	L76 S79	L76-R81 HydrophobicContact CD2-CB 4.33Å; L76-R81 PolarHBondContact O-N 2.82Å; S79-R81 PolarHBondContact O-N 3.46Å; S79-R81 WeakPolarHBondContact OG-CG 3.47Å
82	C	83.8	Confident	85.2	Confident	24 Å²	24	64.6 Å²	64.6	16%	0.162	35%	0.349	C	S	.	.	E	Extended strand (participates in β ladder)	trans	-93.5	111.1	178.4	-156.3	0	0	0	0	109.4	C57 E58 F77 G80	C57-C82 WeakPolarHBondContact CA-SG 3.42Å; C57-C82 HydrophobicContact CB-CB 4.37Å; C57-C82 WeakPolarHBondContact CB-SG 3.49Å; C57-C82 WeakPolarHBondContact SG-CA 3.4Å; C57-C82 WeakPolarHBondContact SG-CB 3.1Å; C57-C82 CovalentContact SG-SG 2.02Å; C57-C82 PolarHBondContact SG-SG 2.93Å; E58-C82 CarbonylContact O-C 3.58Å; E58-C82 WeakPolarHBondContact O-CA 3.48Å; F77-C82 HydrophobicContact CB-CB 4.45Å; F77-C82 HydrophobicContact CD2-CB 4.13Å; G80-C82 PolarHBondContact O-N 2.92Å
83	S	83.6	Confident	85.7	Confident	73 Å²	73	65.1 Å²	65.1	51%	0.51	35%	0.346	S	S	.	.	E	Extended strand (participates in β ladder)	trans	-77.5	-40.7	179.1	57.5	0	0	0	0	111.2	E58	E58-S83 PolarHBondContact O-N 3.47Å; E58-S83 PolarHBondContact O-OG 2.92Å
84	N	85.7	Confident	86	Confident	92 Å²	92	64.3 Å²	64.3	49%	0.492	34%	0.342	S	S	.	.	E	Extended strand (participates in β ladder)	trans	-148.3	148.8	-179.3	-161.8	13.2	0	0	0	112.4	E58	E58-N84 HydrophobicContact CB-CB 4.4Å; E58-N84 PolarHBondContact N-O 2.86Å
85	I	87.1	Confident	86.3	Confident	36 Å²	36	63.3 Å²	63.3	19%	0.185	34%	0.336	C	S	.	.	E	Extended strand (participates in β ladder)	trans	-106.8	122.5	175.3	-63	164.9	0	0	0	108.7	W55 F77 W87 I102	W55-I85 HydrophobicContact CB-CG2 3.98Å; W55-I85 HydrophobicContact CE3-CG2 4.15Å; F77-I85 HydrophobicContact CD2-CD1 3.89Å; F77-I85 HydrophobicContact CD2-CG1 4.43Å; F77-I85 HydrophobicContact CE2-CD1 3.51Å; F77-I85 HydrophobicContact CE2-CG1 4.43Å; F77-I85 HydrophobicContact CZ-CD1 4.25Å; I85-W87 HydrophobicContact CG2-CD2 4.17Å; I85-W87 HydrophobicContact CG2-CZ2 3.96Å; I85-I102 HydrophobicContact CD1-CD1 3.8Å
86	T	86.9	Confident	86.5	Confident	36 Å²	36	58.2 Å²	58.2	22%	0.221	31%	0.313	C	S	.	.	E	Extended strand (participates in β ladder)	trans	-102.1	124.2	172.8	45.1	0	0	0	0	109.8	W55 T56 E58	W55-T86 CarbonylContact C-O 3.56Å; W55-T86 VanDerWaalsContact CA-O 3.24Å; W55-T86 WeakPolarHBondContact CA-O 3.19Å; T56-T86 PolarHBondContact N-O 3.35Å; T56-T86 PolarHBondContact O-N 2.87Å; T56-T86 PolarHBondContact O-OG1 2.85Å; T56-T86 PolarHBondContact OG1-OG1 3.1Å; E58-T86 WeakPolarHBondContact OE1-CG2 3.1Å
87	W	87.5	Confident	86.8	Confident	64 Å²	64	58 Å²	58	24%	0.242	31%	0.313	C	S	.	.	E	Extended strand (participates in β ladder)	trans	-97.7	133.1	-179.6	-59.6	95.7	0	0	0	110.7	P53 W55 I85 V90 V96 V97 I102	P53-W87 HydrophobicContact CB-CE3 4.12Å; P53-W87 HydrophobicContact CG-CE3 4.23Å; W55-W87 HydrophobicContact CB-CD2 4.2Å; W55-W87 HydrophobicContact CB-CE3 3.61Å; W55-W87 HydrophobicContact CB-CZ3 3.78Å; W55-W87 AromaticContact CD1-CZ3 3.83Å; W55-W87 HydrophobicContact CG-CE3 4.3Å; W55-W87 AromaticContact CG-CZ3 3.96Å; W55-W87 HydrophobicContact CG-CZ3 3.96Å; I85-W87 HydrophobicContact CG2-CD2 4.17Å; I85-W87 HydrophobicContact CG2-CZ2 3.96Å; W87-V90 HydrophobicContact CB-CG2 3.62Å; W87-V96 HydrophobicContact CH2-CG1 4.24Å; W87-V97 HydrophobicContact CD2-CG1 4.37Å; W87-V97 HydrophobicContact CD2-CG2 3.76Å; W87-V97 HydrophobicContact CE3-CG2 3.85Å; W87-V97 HydrophobicContact CG-CG1 4.36Å; W87-V97 HydrophobicContact CG-CG2 4.28Å; W87-V97 HydrophobicContact CH2-CG2 4.25Å; W87-V97 HydrophobicContact CZ2-CB 4.41Å; W87-V97 HydrophobicContact CZ2-CG2 4.17Å; W87-V97 HydrophobicContact CZ3-CG2 4.11Å; W87-I102 HydrophobicContact CH2-CG2 3.65Å; W87-I102 HydrophobicContact CZ3-CG2 4.29Å
88	H	84.6	Confident	86.9	Confident	80 Å²	80	57.3 Å²	57.3	37%	0.37	31%	0.311	S	S	.	.	E	Extended strand (participates in β ladder)	trans	-112.9	149.9	-179.6	-58.6	-71.4	0	0	0	110.8	K54 T56 V90	K54-H88 HydrophobicContact CB-CB 4.22Å; K54-H88 PolarHBondContact O-N 2.86Å; T56-H88 PolarHBondContact OG1-NE2 3.23Å; H88-V90 VanDerWaalsContact C-N 3.28Å; H88-V90 PolarHBondContact O-N 2.97Å
89	D	79	Confident	87.1	Confident	124 Å²	124	54.9 Å²	54.9	66%	0.663	30%	0.297	S	S	*	.			trans	57	31.8	174.5	-59.1	-35.3	0	0	0	115.3	S91	D89-S91 VanDerWaalsContact C-N 3.34Å; D89-S91 PolarHBondContact O-N 3.02Å
90	V	79.4	Confident	87.1	Confident	59 Å²	59	52.6 Å²	52.6	36%	0.358	29%	0.285	S	S	.	.			trans	-72.9	84.4	-179.2	-170.2	0	0	0	0	111	P53 W87 H88 F92	P53-V90 HydrophobicContact CB-CG2 3.99Å; P53-V90 HydrophobicContact CG-CG2 4.16Å; W87-V90 HydrophobicContact CB-CG2 3.62Å; H88-V90 VanDerWaalsContact C-N 3.28Å; H88-V90 PolarHBondContact O-N 2.97Å; V90-F92 WeakPolarHBondContact CG1-O 3.49Å
91	S	81.4	Confident	87.4	Confident	63 Å²	63	50 Å²	50	44%	0.441	26%	0.257	S	S	.	.	S	Bend	trans	-81.2	-16.6	175.3	-60.1	0	0	0	0	113.6	D89 Y330	D89-S91 VanDerWaalsContact C-N 3.34Å; D89-S91 PolarHBondContact O-N 3.02Å; S91-Y330 PolarHBondContact O-OH 3.13Å
92	F	87.7	Confident	87.6	Confident	3 Å²	3	41.8 Å²	41.8	1%	0.013	23%	0.226	C	C	.	.	S	Bend	trans	-144.6	131.6	178.5	-179.3	-91.8	0	0	0	107	Y48 V90 P94 A205 W211 L214 Y330	Y48-F92 WeakPolarHBondContact O-CD1 3.3Å; V90-F92 WeakPolarHBondContact CG1-O 3.49Å; F92-P94 HydrophobicContact CD1-CB 4.32Å; F92-P94 WeakPolarHBondContact O-CD 3.48Å; F92-A205 HydrophobicContact CE2-CB 4.47Å; F92-W211 HydrophobicContact CE1-CB 4.03Å; F92-W211 HydrophobicContact CZ-CB 4.2Å; F92-L214 HydrophobicContact CE2-CB 4.42Å; F92-L214 HydrophobicContact CE2-CD2 4Å; F92-L214 HydrophobicContact CZ-CB 4.15Å; F92-L214 HydrophobicContact CZ-CD2 3.62Å; F92-Y330 WeakPolarHBondContact CB-OH 3.13Å; F92-Y330 WeakPolarHBondContact CD2-OH 3.23Å
93	Y	92.6	Very high	87.8	Confident	80 Å²	80	41.5 Å²	41.5	31%	0.314	22%	0.224	S	C	.	.	B	Isolated β-bridge	trans	-81.1	105.1	178.1	-170.3	-96.8	0	0	0	110.7	V97 E98 Q209 H210 W211	Y93-V97 HydrophobicContact CD2-CB 4.48Å; Y93-V97 HydrophobicContact CD2-CG1 4.11Å; Y93-V97 HydrophobicContact CE2-CB 4.08Å; Y93-V97 HydrophobicContact CE2-CG1 3.42Å; Y93-V97 VanDerWaalsContact CE2-CG1 3.42Å; Y93-E98 HydrophobicContact CE1-CB 3.81Å; Y93-E98 HydrophobicContact CE1-CG 4.16Å; Y93-E98 WeakPolarHBondContact OH-CA 3.45Å; Y93-Q209 PolarHBondContact N-O 2.83Å; Y93-H210 AromaticContact CD1-CD2 3.59Å; Y93-H210 AromaticContact CD1-CE1 3.59Å; Y93-H210 AromaticContact CD1-NE2 3.23Å; Y93-H210 WeakPolarHBondContact CD1-NE2 3.4Å; Y93-H210 AromaticContact CE1-CE1 3.97Å; Y93-H210 AromaticContact CE1-NE2 3.59Å; Y93-W211 PolarHBondContact O-N 3.49Å; Y93-W211 VanDerWaalsContact O-N 3.09Å
94	P	93.4	Very high	88	Confident	0 Å²	0	41.6 Å²	41.6	0%	0	23%	0.225	C	C	.	.			trans	-95.1	167.9	-174.1	36	-24	0	0	0	112.1	A49 L51 P53 F92 V96 V97 E98	A49-P94 WeakPolarHBondContact O-CB 3.26Å; L51-P94 HydrophobicContact CB-CB 4.45Å; L51-P94 WeakPolarHBondContact O-CB 2.91Å; L51-P94 WeakPolarHBondContact O-CG 3.06Å; P53-P94 HydrophobicContact CG-CG 3.92Å; F92-P94 HydrophobicContact CD1-CB 4.32Å; F92-P94 WeakPolarHBondContact O-CD 3.48Å; P94-V96 HydrophobicContact CG-CB 4.44Å; P94-V96 PolarHBondContact O-N 2.94Å; P94-V97 HydrophobicContact CG-CB 4.37Å; P94-V97 HydrophobicContact CG-CG2 3.73Å; P94-V97 PolarHBondContact O-N 3.08Å; P94-E98 PolarHBondContact O-N 2.89Å
95	I	93.1	Very high	88.2	Confident	0 Å²	0	42.7 Å²	42.7	0%	0	23%	0.225	C	C	.	.	H	α-helix	trans	-57	-33.7	177	-63.4	168	0	0	0	111.2	Y45 M46 A49 V97 E98 W99 L101 I109 M112 L154 W211	Y45-I95 HydrophobicContact CE1-CD1 4.28Å; M46-I95 HydrophobicContact SD-CD1 4.34Å; A49-I95 HydrophobicContact CB-CD1 3.72Å; A49-I95 HydrophobicContact CB-CG1 4.03Å; A49-I95 WeakPolarHBondContact O-CB 3.21Å; A49-I95 PolarHBondContact O-N 3.1Å; I95-V97 VanDerWaalsContact C-N 3.31Å; I95-V97 PolarHBondContact O-N 3.27Å; I95-E98 PolarHBondContact O-N 2.92Å; I95-W99 HydrophobicContact CG2-CD2 3.97Å; I95-W99 HydrophobicContact CG2-CE3 3.11Å; I95-W99 HydrophobicContact CG2-CH2 4.34Å; I95-W99 HydrophobicContact CG2-CZ3 3.33Å; I95-W99 PolarHBondContact O-N 3.39Å; I95-L101 HydrophobicContact CG2-CD1 4.06Å; I95-I109 HydrophobicContact CB-CD1 4.45Å; I95-I109 HydrophobicContact CG2-CD1 4.23Å; I95-M112 HydrophobicContact CD1-CE 4.23Å; I95-L154 HydrophobicContact CD1-CD2 3.75Å; I95-L154 HydrophobicContact CG1-CD2 4.38Å; I95-W211 HydrophobicContact CG1-CB 4.14Å; I95-W211 HydrophobicContact CG1-CD2 3.64Å; I95-W211 HydrophobicContact CG1-CE3 4.06Å; I95-W211 HydrophobicContact CG1-CG 3.73Å
96	V	91.9	Very high	88.2	Confident	0 Å²	0	42 Å²	42	0%	0	22%	0.22	C	C	.	.	H	α-helix	trans	-62.6	-38.8	-175.1	-179.3	0	0	0	0	111.6	L51 E52 W87 P94 G100 L101 I102 I109	L51-V96 WeakPolarHBondContact O-CG2 3.35Å; E52-V96 HydrophobicContact CG-CG1 4.38Å; W87-V96 HydrophobicContact CH2-CG1 4.24Å; P94-V96 HydrophobicContact CG-CB 4.44Å; P94-V96 PolarHBondContact O-N 2.94Å; V96-G100 VanDerWaalsContact O-CA 3.25Å; V96-G100 WeakPolarHBondContact O-CA 3.26Å; V96-G100 PolarHBondContact O-N 3.22Å; V96-L101 PolarHBondContact O-N 2.87Å; V96-L101 VanDerWaalsContact O-N 3.14Å; V96-I102 HydrophobicContact CG1-CG2 3.86Å; V96-I109 HydrophobicContact CG2-CD1 3.98Å; V96-I109 HydrophobicContact CG2-CG1 4.07Å
97	V	91.6	Very high	88.1	Confident	23 Å²	23	42.7 Å²	42.7	14%	0.139	23%	0.227	C	C	.	.	H	α-helix	trans	-73.2	-41.8	177.6	175.3	0	0	0	0	110.5	P53 W87 Y93 P94 I95	P53-V97 HydrophobicContact CG-CG2 3.89Å; W87-V97 HydrophobicContact CD2-CG1 4.37Å; W87-V97 HydrophobicContact CD2-CG2 3.76Å; W87-V97 HydrophobicContact CE3-CG2 3.85Å; W87-V97 HydrophobicContact CG-CG1 4.36Å; W87-V97 HydrophobicContact CG-CG2 4.28Å; W87-V97 HydrophobicContact CH2-CG2 4.25Å; W87-V97 HydrophobicContact CZ2-CB 4.41Å; W87-V97 HydrophobicContact CZ2-CG2 4.17Å; W87-V97 HydrophobicContact CZ3-CG2 4.11Å; Y93-V97 HydrophobicContact CD2-CB 4.48Å; Y93-V97 HydrophobicContact CD2-CG1 4.11Å; Y93-V97 HydrophobicContact CE2-CB 4.08Å; Y93-V97 HydrophobicContact CE2-CG1 3.42Å; Y93-V97 VanDerWaalsContact CE2-CG1 3.42Å; P94-V97 HydrophobicContact CG-CB 4.37Å; P94-V97 HydrophobicContact CG-CG2 3.73Å; P94-V97 PolarHBondContact O-N 3.08Å; I95-V97 VanDerWaalsContact C-N 3.31Å; I95-V97 PolarHBondContact O-N 3.27Å
98	E	90.5	Very high	88.3	Confident	45 Å²	45	40.8 Å²	40.8	21%	0.21	22%	0.221	C	C	.	.	H	α-helix	trans	-68	-41.5	-176.6	-163.7	-178.8	124.9	0	0	113.1	Y93 P94 I95 H210 W211 R212	Y93-E98 HydrophobicContact CE1-CB 3.81Å; Y93-E98 HydrophobicContact CE1-CG 4.16Å; Y93-E98 WeakPolarHBondContact OH-CA 3.45Å; P94-E98 PolarHBondContact O-N 2.89Å; I95-E98 PolarHBondContact O-N 2.92Å; E98-H210 IonicContact OE2-CE1 2.66Å; E98-W211 VanDerWaalsContact OE2-CE2 3.23Å; E98-W211 VanDerWaalsContact OE2-CZ2 3.28Å; E98-W211 WeakPolarHBondContact OE2-CZ2 3.38Å; E98-W211 PolarHBondContact OE2-NE1 3.45Å; E98-R212 IonicContact OE1-CZ 3.49Å; E98-R212 VanDerWaalsContact OE1-CZ 3.29Å; E98-R212 IonicContact OE1-NE 3.87Å; E98-R212 PolarHBondContact OE1-NE 2.84Å; E98-R212 IonicContact OE1-NH2 3.7Å; E98-R212 PolarHBondContact OE1-NH2 3.15Å; E98-R212 IonicContact OE2-CZ 2.67Å; E98-R212 IonicContact OE2-NE 2.68Å; E98-R212 PolarHBondContact OE2-NE 2.88Å; E98-R212 IonicContact OE2-NH2 3.66Å
99	W	91.5	Very high	88.6	Confident	51 Å²	51	37.1 Å²	37.1	19%	0.193	20%	0.204	C	C	.	.	H	α-helix	trans	-108	5.5	-175.4	-62.5	-22.8	0	0	0	114	I95 L101 W151 L154 W211	I95-W99 HydrophobicContact CG2-CD2 3.97Å; I95-W99 HydrophobicContact CG2-CE3 3.11Å; I95-W99 HydrophobicContact CG2-CH2 4.34Å; I95-W99 HydrophobicContact CG2-CZ3 3.33Å; I95-W99 PolarHBondContact O-N 3.39Å; W99-L101 VanDerWaalsContact C-N 3.34Å; W99-L101 HydrophobicContact CB-CD1 4.31Å; W99-L101 HydrophobicContact CB-CD2 4.39Å; W99-L101 HydrophobicContact CB-CG 3.94Å; W99-L101 HydrophobicContact CE3-CD1 4.15Å; W99-L101 PolarHBondContact O-N 2.81Å; W99-W151 HydrophobicContact CD2-CB 4.24Å; W99-W151 HydrophobicContact CE3-CB 3.34Å; W99-W151 HydrophobicContact CE3-CG 4.49Å; W99-W151 VanDerWaalsContact CH2-CA 3.48Å; W99-W151 HydrophobicContact CH2-CB 3.97Å; W99-W151 HydrophobicContact CZ3-CB 3.19Å; W99-L154 HydrophobicContact CH2-CB 3.96Å; W99-L154 HydrophobicContact CH2-CD2 3.61Å; W99-L154 HydrophobicContact CH2-CG 4.45Å; W99-L154 HydrophobicContact CZ3-CB 4.46Å; W99-L154 HydrophobicContact CZ3-CD2 3.85Å; W99-W211 AromaticContact CH2-CH2 3.86Å; W99-W211 HydrophobicContact CH2-CH2 3.86Å; W99-W211 HydrophobicContact CH2-CZ2 4.17Å; W99-W211 AromaticContact CZ2-CH2 3.81Å; W99-W211 HydrophobicContact CZ2-CH2 3.81Å; W99-W211 AromaticContact CZ2-CZ2 3.86Å; W99-W211 HydrophobicContact CZ2-CZ2 3.86Å
100	G	88.2	Confident	88.9	Confident	20 Å²	20	32.4 Å²	32.4	21%	0.206	18%	0.177	C	C	.	.	T	Hydrogen-bonded Turn	trans	59.5	40.2	178.3	0	0	0	0	0	113.6	V96 I102	V96-G100 VanDerWaalsContact O-CA 3.25Å; V96-G100 WeakPolarHBondContact O-CA 3.26Å; V96-G100 PolarHBondContact O-N 3.22Å; G100-I102 VanDerWaalsContact C-N 3.26Å; G100-I102 PolarHBondContact O-N 3.4Å
101	L	90.6	Very high	89.4	Confident	5 Å²	5	33.5 Å²	33.5	3%	0.026	18%	0.18	C	C	.	.			trans	-84.9	60	-175.1	-60.5	-179.6	0	0	0	112.5	I95 V96 W99 K105 R106 I108 I109	I95-L101 HydrophobicContact CG2-CD1 4.06Å; V96-L101 PolarHBondContact O-N 2.87Å; V96-L101 VanDerWaalsContact O-N 3.14Å; W99-L101 VanDerWaalsContact C-N 3.34Å; W99-L101 HydrophobicContact CB-CD1 4.31Å; W99-L101 HydrophobicContact CB-CD2 4.39Å; W99-L101 HydrophobicContact CB-CG 3.94Å; W99-L101 HydrophobicContact CE3-CD1 4.15Å; W99-L101 PolarHBondContact O-N 2.81Å; L101-K105 HydrophobicContact CD2-CB 4.15Å; L101-R106 WeakPolarHBondContact O-CA 3.25Å; L101-R106 WeakPolarHBondContact O-CD 3.28Å; L101-I108 HydrophobicContact CD1-CB 4.44Å; L101-I108 HydrophobicContact CD1-CG2 4.07Å; L101-I108 HydrophobicContact CD2-CB 4.43Å; L101-I108 HydrophobicContact CD2-CD1 3.82Å; L101-I108 HydrophobicContact CD2-CG2 4.49Å; L101-I109 HydrophobicContact CB-CD1 4.41Å; L101-I109 HydrophobicContact CB-CG1 4.34Å; L101-I109 HydrophobicContact CD1-CD1 3.68Å; L101-I109 HydrophobicContact CD1-CG1 4.3Å
102	I	89.9	Confident	89.8	Confident	0 Å²	0	30.5 Å²	30.5	0%	0	16%	0.159	C	C	.	.			trans	-105.7	168.9	178.3	58.6	177.3	0	0	0	111.6	W55 F77 I85 W87 V96 G100 S104 K105 R106	W55-I102 HydrophobicContact CD2-CD1 4.19Å; W55-I102 HydrophobicContact CE3-CD1 4.2Å; W55-I102 HydrophobicContact CH2-CD1 3.85Å; W55-I102 HydrophobicContact CZ2-CB 4.37Å; W55-I102 HydrophobicContact CZ2-CD1 3.84Å; W55-I102 HydrophobicContact CZ3-CD1 4.02Å; F77-I102 HydrophobicContact CD1-CD1 3.91Å; F77-I102 HydrophobicContact CD1-CG1 4Å; F77-I102 HydrophobicContact CD2-CD1 4.23Å; F77-I102 HydrophobicContact CE1-CD1 3.84Å; F77-I102 HydrophobicContact CE1-CG1 3.67Å; F77-I102 HydrophobicContact CE2-CD1 4.21Å; F77-I102 HydrophobicContact CG-CD1 4.09Å; F77-I102 HydrophobicContact CZ-CD1 3.99Å; F77-I102 HydrophobicContact CZ-CG1 4.11Å; I85-I102 HydrophobicContact CD1-CD1 3.8Å; W87-I102 HydrophobicContact CH2-CG2 3.65Å; W87-I102 HydrophobicContact CZ3-CG2 4.29Å; V96-I102 HydrophobicContact CG1-CG2 3.86Å; G100-I102 VanDerWaalsContact C-N 3.26Å; G100-I102 PolarHBondContact O-N 3.4Å; I102-S104 PolarHBondContact O-N 3.42Å; I102-K105 PolarHBondContact O-N 3.33Å; I102-R106 PolarHBondContact O-N 2.98Å
103	C	88.1	Confident	89.9	Confident	17 Å²	17	30.5 Å²	30.5	12%	0.115	16%	0.159	C	C	.	.	G	3₁₀ helix	trans	53.3	-126.4	174.3	-52.5	0	0	0	0	113.2	C74 E78 K105 R106	C74-C103 WeakPolarHBondContact CA-SG 3.25Å; C74-C103 HydrophobicContact CB-CB 3.66Å; C74-C103 WeakPolarHBondContact CB-SG 3.42Å; C74-C103 VanDerWaalsContact SG-CA 3.54Å; C74-C103 WeakPolarHBondContact SG-CB 3.26Å; C74-C103 CovalentContact SG-SG 2.04Å; C74-C103 PolarHBondContact SG-SG 3Å; E78-C103 HydrophobicContact CG-CB 4.42Å; E78-C103 WeakPolarHBondContact OE1-CB 3.46Å; C103-K105 VanDerWaalsContact C-N 3.27Å; C103-K105 PolarHBondContact O-N 2.7Å; C103-R106 WeakPolarHBondContact O-CB 3.23Å; C103-R106 PolarHBondContact O-N 3.32Å
104	S	87.4	Confident	89.7	Confident	76 Å²	76	28.2 Å²	28.2	53%	0.531	15%	0.153	S	C	.	.	G	3₁₀ helix	trans	-55.1	-37.7	176.6	49.8	0	0	0	0	114	E78 I102 R106 S107	E78-S104 WeakPolarHBondContact OE1-CB 3.41Å; E78-S104 PolarHBondContact OE1-N 3.4Å; E78-S104 PolarHBondContact OE1-OG 2.94Å; I102-S104 PolarHBondContact O-N 3.42Å; S104-R106 PolarHBondContact O-N 2.93Å; S104-S107 PolarHBondContact O-OG 3.01Å
105	K	89	Confident	89.6	Confident	115 Å²	115	30.6 Å²	30.6	50%	0.5	17%	0.166	S	C	.	.	G	3₁₀ helix	trans	-73.5	-12.6	179	-68.2	-173.7	-179.5	177.1	0	113.5	L101 I102 C103 S107 I108	L101-K105 HydrophobicContact CD2-CB 4.15Å; I102-K105 PolarHBondContact O-N 3.33Å; C103-K105 VanDerWaalsContact C-N 3.27Å; C103-K105 PolarHBondContact O-N 2.7Å; K105-S107 PolarHBondContact O-N 3.24Å; K105-I108 HydrophobicContact CB-CD1 4.21Å; K105-I108 WeakPolarHBondContact O-CB 3.29Å; K105-I108 WeakPolarHBondContact O-CG1 3.15Å; K105-I108 PolarHBondContact O-N 3.32Å
106	R	87.1	Confident	89.4	Confident	21 Å²	21	31 Å²	31	8%	0.079	17%	0.168	C	C	.	.	G	3₁₀ helix	trans	-59.8	-31	176.9	-176.3	66.6	175.7	177.4	3	112.9	G50 E52 L101 I102 C103 S104 I108 I109 Y110	G50-R106 PolarHBondContact O-NH1 2.72Å; G50-R106 PolarHBondContact O-NH2 3.42Å; E52-R106 IonicContact OE2-CZ 3.69Å; E52-R106 IonicContact OE2-NE 3.9Å; E52-R106 PolarHBondContact OE2-NE 2.61Å; L101-R106 WeakPolarHBondContact O-CA 3.25Å; L101-R106 WeakPolarHBondContact O-CD 3.28Å; I102-R106 PolarHBondContact O-N 2.98Å; C103-R106 WeakPolarHBondContact O-CB 3.23Å; C103-R106 PolarHBondContact O-N 3.32Å; S104-R106 PolarHBondContact O-N 2.93Å; R106-I108 PolarHBondContact O-N 2.98Å; R106-I109 WeakPolarHBondContact O-CB 3.48Å; R106-I109 PolarHBondContact O-N 3.47Å; R106-Y110 HydrophobicContact CG-CE2 3.93Å
107	S	86.4	Confident	89.2	Confident	51 Å²	51	31.4 Å²	31.4	36%	0.357	17%	0.169	S	C	.	.	H	α-helix	trans	-50.1	-30.5	174.4	58.1	0	0	0	0	112.8	S104 K105 I109 Y110 I111	S104-S107 PolarHBondContact O-OG 3.01Å; K105-S107 PolarHBondContact O-N 3.24Å; S107-I109 VanDerWaalsContact C-N 3.33Å; S107-I109 PolarHBondContact O-N 3Å; S107-Y110 PolarHBondContact O-N 3.3Å; S107-I111 WeakPolarHBondContact O-CG1 3.5Å; S107-I111 PolarHBondContact O-N 2.89Å
108	I	90.8	Very high	89	Confident	24 Å²	24	33.3 Å²	33.3	12%	0.123	18%	0.181	C	C	.	.	H	α-helix	trans	-59.7	-40.1	177	-64.1	169.1	0	0	0	111.7	L101 K105 R106 Y110 I111 M112 W151	L101-I108 HydrophobicContact CD1-CB 4.44Å; L101-I108 HydrophobicContact CD1-CG2 4.07Å; L101-I108 HydrophobicContact CD2-CB 4.43Å; L101-I108 HydrophobicContact CD2-CD1 3.82Å; L101-I108 HydrophobicContact CD2-CG2 4.49Å; K105-I108 HydrophobicContact CB-CD1 4.21Å; K105-I108 WeakPolarHBondContact O-CB 3.29Å; K105-I108 WeakPolarHBondContact O-CG1 3.15Å; K105-I108 PolarHBondContact O-N 3.32Å; R106-I108 PolarHBondContact O-N 2.98Å; I108-Y110 VanDerWaalsContact C-N 3.34Å; I108-Y110 PolarHBondContact O-N 2.92Å; I108-I111 PolarHBondContact O-N 3.33Å; I108-M112 HydrophobicContact CG2-CG 4.33Å; I108-M112 HydrophobicContact CG2-SD 4.11Å; I108-M112 VanDerWaalsContact O-CG 3.27Å; I108-M112 WeakPolarHBondContact O-CG 3.45Å; I108-M112 PolarHBondContact O-N 3.44Å; I108-W151 HydrophobicContact CD1-CZ2 4.26Å; I108-W151 HydrophobicContact CG2-CD2 3.61Å; I108-W151 HydrophobicContact CG2-CE3 3.44Å; I108-W151 VanDerWaalsContact CG2-CE3 3.44Å; I108-W151 HydrophobicContact CG2-CG 4.18Å; I108-W151 HydrophobicContact CG2-CH2 4.26Å; I108-W151 HydrophobicContact CG2-CZ2 4.41Å; I108-W151 HydrophobicContact CG2-CZ3 3.79Å
109	I	90	Very high	88.9	Confident	2 Å²	2	31.2 Å²	31.2	1%	0.01	17%	0.171	C	C	.	.	H	α-helix	trans	-61.1	-44.7	177.4	-62.9	-60.8	0	0	0	110.5	M46 I95 V96 L101 R106 S107 M112 M113	M46-I109 HydrophobicContact CE-CG2 3.62Å; I95-I109 HydrophobicContact CB-CD1 4.45Å; I95-I109 HydrophobicContact CG2-CD1 4.23Å; V96-I109 HydrophobicContact CG2-CD1 3.98Å; V96-I109 HydrophobicContact CG2-CG1 4.07Å; L101-I109 HydrophobicContact CB-CD1 4.41Å; L101-I109 HydrophobicContact CB-CG1 4.34Å; L101-I109 HydrophobicContact CD1-CD1 3.68Å; L101-I109 HydrophobicContact CD1-CG1 4.3Å; R106-I109 WeakPolarHBondContact O-CB 3.48Å; R106-I109 PolarHBondContact O-N 3.47Å; S107-I109 VanDerWaalsContact C-N 3.33Å; S107-I109 PolarHBondContact O-N 3Å; I109-M112 PolarHBondContact O-N 3.42Å; I109-M113 HydrophobicContact CG2-SD 4.45Å; I109-M113 WeakPolarHBondContact O-CG 3.25Å; I109-M113 PolarHBondContact O-N 3.45Å
110	Y	87.3	Confident	88.6	Confident	25 Å²	25	29.6 Å²	29.6	10%	0.098	17%	0.166	C	C	.	.	H	α-helix	trans	-67.3	-36.7	177.6	-57	-56.8	0	0	0	112	R106 S107 I108 M113 T114 P441 L444 Y445 R448	R106-Y110 HydrophobicContact CG-CE2 3.93Å; S107-Y110 PolarHBondContact O-N 3.3Å; I108-Y110 VanDerWaalsContact C-N 3.34Å; I108-Y110 PolarHBondContact O-N 2.92Å; Y110-M113 HydrophobicContact CD1-SD 4.38Å; Y110-M113 PolarHBondContact O-N 3.48Å; Y110-T114 WeakPolarHBondContact O-CB 3.5Å; Y110-T114 PolarHBondContact O-N 3.2Å; Y110-T114 PolarHBondContact O-OG1 2.66Å; Y110-P441 HydrophobicContact CD1-CB 4.34Å; Y110-P441 WeakPolarHBondContact O-CB 3.39Å; Y110-L444 HydrophobicContact CD1-CB 4.14Å; Y110-L444 HydrophobicContact CE1-CB 3.6Å; Y110-L444 HydrophobicContact CE1-CD1 4.3Å; Y110-Y445 HydrophobicContact CD2-CD2 4.25Å; Y110-Y445 HydrophobicContact CE2-CD2 4.31Å; Y110-R448 PolarHBondContact OH-NE 3.31Å
111	I	89	Confident	88.5	Confident	82 Å²	82	31.1 Å²	31.1	42%	0.421	17%	0.169	S	C	.	.	H	α-helix	trans	-63.3	-45.4	173.4	-69.5	165.1	0	0	0	110.4	S107 I108 M113 T114 I115	S107-I111 WeakPolarHBondContact O-CG1 3.5Å; S107-I111 PolarHBondContact O-N 2.89Å; I108-I111 PolarHBondContact O-N 3.33Å; I111-M113 PolarHBondContact O-N 2.88Å; I111-T114 CarbonylContact O-C 3.58Å; I111-T114 WeakPolarHBondContact O-CB 3.48Å; I111-T114 PolarHBondContact O-N 3.49Å; I111-T114 VanDerWaalsContact O-N 3.11Å; I111-I115 HydrophobicContact CG2-CD1 3.68Å; I111-I115 HydrophobicContact CG2-CG1 4.23Å; I111-I115 WeakPolarHBondContact O-CB 3.36Å; I111-I115 VanDerWaalsContact O-CG1 3.28Å; I111-I115 WeakPolarHBondContact O-CG1 3.23Å; I111-I115 PolarHBondContact O-N 2.73Å
112	M	90.5	Very high	88.2	Confident	0 Å²	0	33.7 Å²	33.7	0%	0	19%	0.185	C	C	.	.	H	α-helix	trans	-60.4	-44.1	177.8	-71.6	173.7	68.2	0	0	112.2	M46 I95 I108 I109 T114 I115 Q116 W151 L154 A155 M158	M46-M112 HydrophobicContact CE-CB 4.3Å; I95-M112 HydrophobicContact CD1-CE 4.23Å; I108-M112 HydrophobicContact CG2-CG 4.33Å; I108-M112 HydrophobicContact CG2-SD 4.11Å; I108-M112 VanDerWaalsContact O-CG 3.27Å; I108-M112 WeakPolarHBondContact O-CG 3.45Å; I108-M112 PolarHBondContact O-N 3.44Å; I109-M112 PolarHBondContact O-N 3.42Å; M112-T114 VanDerWaalsContact C-N 3.32Å; M112-T114 PolarHBondContact O-N 3.24Å; M112-I115 PolarHBondContact O-N 2.65Å; M112-Q116 PolarHBondContact O-N 3.38Å; M112-W151 HydrophobicContact CG-CE3 4.42Å; M112-W151 HydrophobicContact SD-CB 4.35Å; M112-L154 HydrophobicContact CE-CB 4.16Å; M112-L154 HydrophobicContact CE-CD2 3.61Å; M112-L154 HydrophobicContact CE-CG 3.71Å; M112-A155 HydrophobicContact CG-CB 4.08Å; M112-M158 HydrophobicContact CB-SD 4.47Å; M112-M158 HydrophobicContact CE-SD 3.75Å
113	M	88.6	Confident	87.9	Confident	4 Å²	4	33.7 Å²	33.7	2%	0.02	19%	0.185	C	C	.	.	H	α-helix	trans	-60.3	-44.3	173.2	-65.4	171	74.1	0	0	111.1	M46 I109 Y110 I111 I115 Q116 M117 Y320 P441 L444	M46-M113 HydrophobicContact CB-CE 4.19Å; M46-M113 HydrophobicContact CB-CG 3.71Å; M46-M113 HydrophobicContact CB-SD 4.14Å; M46-M113 HydrophobicContact CE-CG 3.59Å; M46-M113 HydrophobicContact CE-SD 4.39Å; M46-M113 HydrophobicContact CG-CG 3.66Å; M46-M113 HydrophobicContact SD-CG 4.46Å; I109-M113 HydrophobicContact CG2-SD 4.45Å; I109-M113 WeakPolarHBondContact O-CG 3.25Å; I109-M113 PolarHBondContact O-N 3.45Å; Y110-M113 HydrophobicContact CD1-SD 4.38Å; Y110-M113 PolarHBondContact O-N 3.48Å; I111-M113 PolarHBondContact O-N 2.88Å; M113-I115 PolarHBondContact O-N 2.9Å; M113-Q116 PolarHBondContact O-N 3.04Å; M113-M117 VanDerWaalsContact O-CG 3.29Å; M113-M117 WeakPolarHBondContact O-CG 3.49Å; M113-M117 PolarHBondContact O-N 2.95Å; M113-M117 VanDerWaalsContact O-N 3.07Å; M113-Y320 HydrophobicContact CE-CD1 3.92Å; M113-Y320 HydrophobicContact CE-CD2 3.91Å; M113-Y320 HydrophobicContact CE-CE1 3.52Å; M113-Y320 HydrophobicContact CE-CE2 3.46Å; M113-Y320 VanDerWaalsContact CE-CE2 3.46Å; M113-Y320 HydrophobicContact CE-CG 4.13Å; M113-P441 HydrophobicContact CB-CB 4.1Å; M113-P441 HydrophobicContact CB-CG 3.41Å; M113-P441 VanDerWaalsContact CB-CG 3.41Å; M113-P441 HydrophobicContact CE-CG 4.29Å; M113-P441 HydrophobicContact CG-CG 4.48Å; M113-P441 HydrophobicContact SD-CG 4.44Å; M113-L444 HydrophobicContact CE-CD1 3.83Å; M113-L444 HydrophobicContact SD-CD1 4.35Å
114	T	88.8	Confident	87.5	Confident	31 Å²	31	33.2 Å²	33.2	19%	0.19	18%	0.182	C	C	.	.	H	α-helix	trans	-62.4	-44.4	178.6	-56.3	0	0	0	0	111	Y110 I111 M112 Q116 M117 V118 Q442	Y110-T114 WeakPolarHBondContact O-CB 3.5Å; Y110-T114 PolarHBondContact O-N 3.2Å; Y110-T114 PolarHBondContact O-OG1 2.66Å; I111-T114 CarbonylContact O-C 3.58Å; I111-T114 WeakPolarHBondContact O-CB 3.48Å; I111-T114 PolarHBondContact O-N 3.49Å; I111-T114 VanDerWaalsContact O-N 3.11Å; M112-T114 VanDerWaalsContact C-N 3.32Å; M112-T114 PolarHBondContact O-N 3.24Å; T114-Q116 VanDerWaalsContact C-N 3.33Å; T114-Q116 PolarHBondContact O-N 3.45Å; T114-M117 PolarHBondContact O-N 3.37Å; T114-M117 VanDerWaalsContact O-N 3.13Å; T114-V118 HydrophobicContact CG2-CG2 4.21Å; T114-V118 VanDerWaalsContact O-CG2 3.3Å; T114-V118 WeakPolarHBondContact O-CG2 3.46Å; T114-V118 PolarHBondContact O-N 3.09Å; T114-Q442 PolarHBondContact OG1-NE2 3.06Å
115	I	91.2	Very high	86.9	Confident	50 Å²	50	32 Å²	32	26%	0.256	17%	0.172	S	C	.	.	H	α-helix	trans	-57.7	-45.1	176.8	-73.2	169	0	0	0	110.8	I111 M112 M113 M117 V118 G119 A155 F159	I111-I115 HydrophobicContact CG2-CD1 3.68Å; I111-I115 HydrophobicContact CG2-CG1 4.23Å; I111-I115 WeakPolarHBondContact O-CB 3.36Å; I111-I115 VanDerWaalsContact O-CG1 3.28Å; I111-I115 WeakPolarHBondContact O-CG1 3.23Å; I111-I115 PolarHBondContact O-N 2.73Å; M112-I115 PolarHBondContact O-N 2.65Å; M113-I115 PolarHBondContact O-N 2.9Å; I115-M117 VanDerWaalsContact C-N 3.33Å; I115-M117 PolarHBondContact O-N 2.88Å; I115-V118 PolarHBondContact O-N 3.38Å; I115-G119 PolarHBondContact O-N 3.22Å; I115-A155 HydrophobicContact CD1-CB 4.04Å; I115-A155 WeakPolarHBondContact CG2-O 3.43Å; I115-F159 HydrophobicContact CG2-CB 3.62Å; I115-F159 HydrophobicContact CG2-CD2 4.14Å; I115-F159 HydrophobicContact CG2-CG 4.34Å; I115-F159 WeakPolarHBondContact O-CD2 3.44Å
116	Q	88.9	Confident	86.4	Confident	9 Å²	9	30 Å²	30	4%	0.042	17%	0.166	C	C	.	.	H	α-helix	trans	-60.4	-43.1	175.9	-171	179.5	28.3	0	0	112	N42 M112 M113 T114 G119 L120 M158	N42-Q116 PolarHBondContact O-NE2 3.01Å; M112-Q116 PolarHBondContact O-N 3.38Å; M113-Q116 PolarHBondContact O-N 3.04Å; T114-Q116 VanDerWaalsContact C-N 3.33Å; T114-Q116 PolarHBondContact O-N 3.45Å; Q116-G119 PolarHBondContact O-N 3.16Å; Q116-L120 PolarHBondContact O-N 3.14Å; Q116-M158 HydrophobicContact CB-CB 4.2Å; Q116-M158 HydrophobicContact CB-CE 4.12Å; Q116-M158 HydrophobicContact CG-CB 4.36Å; Q116-M158 HydrophobicContact CG-CE 4.42Å
117	M	86.8	Confident	85.8	Confident	8 Å²	8	29.3 Å²	29.3	4%	0.039	17%	0.165	C	C	.	.	H	α-helix	trans	-71.7	-35	179.9	-63.3	-63.2	168.2	0	0	112.7	M113 T114 I115 G119 L120 L121	M113-M117 VanDerWaalsContact O-CG 3.29Å; M113-M117 WeakPolarHBondContact O-CG 3.49Å; M113-M117 PolarHBondContact O-N 2.95Å; M113-M117 VanDerWaalsContact O-N 3.07Å; T114-M117 PolarHBondContact O-N 3.37Å; T114-M117 VanDerWaalsContact O-N 3.13Å; I115-M117 VanDerWaalsContact C-N 3.33Å; I115-M117 PolarHBondContact O-N 2.88Å; M117-G119 VanDerWaalsContact C-N 3.34Å; M117-L120 WeakPolarHBondContact O-CB 3.41Å; M117-L120 PolarHBondContact O-N 3.29Å; M117-L120 HydrophobicContact SD-CD2 4.11Å; M117-L121 WeakPolarHBondContact O-CB 3.39Å; M117-L121 PolarHBondContact O-N 2.88Å
118	V	88.1	Confident	84.8	Confident	64 Å²	64	29.6 Å²	29.6	39%	0.388	17%	0.17	S	C	.	.	H	α-helix	trans	-63.8	-42.8	171.1	172.2	0	0	0	0	110	T114 I115 L120 L121 V122 F159	T114-V118 HydrophobicContact CG2-CG2 4.21Å; T114-V118 VanDerWaalsContact O-CG2 3.3Å; T114-V118 WeakPolarHBondContact O-CG2 3.46Å; T114-V118 PolarHBondContact O-N 3.09Å; I115-V118 PolarHBondContact O-N 3.38Å; V118-L120 VanDerWaalsContact C-N 3.35Å; V118-L120 PolarHBondContact O-N 3.34Å; V118-L121 PolarHBondContact O-N 3.13Å; V118-V122 HydrophobicContact CG1-CG2 4.21Å; V118-V122 WeakPolarHBondContact O-CG2 3.16Å; V118-V122 PolarHBondContact O-N 2.9Å; V118-F159 HydrophobicContact CG1-CE2 4.27Å
119	G	88.9	Confident	83.7	Confident	0 Å²	0	36.1 Å²	36.1	0%	0	20%	0.2	C	C	.	.	H	α-helix	trans	-51.5	-56.4	169.6	0	0	0	0	0	110.3	I115 Q116 M117 L121 V122 G123 F159 F163	I115-G119 PolarHBondContact O-N 3.22Å; Q116-G119 PolarHBondContact O-N 3.16Å; M117-G119 VanDerWaalsContact C-N 3.34Å; G119-L121 VanDerWaalsContact C-N 3.29Å; G119-L121 PolarHBondContact O-N 3.08Å; G119-V122 PolarHBondContact O-N 3.26Å; G119-G123 PolarHBondContact O-N 3.06Å; G119-F159 VanDerWaalsContact CA-CE2 3.48Å; G119-F163 VanDerWaalsContact C-CA 3.45Å; G119-F163 VanDerWaalsContact C-N 3.3Å; G119-F163 WeakPolarHBondContact O-CA 3.37Å
120	L	85.4	Confident	82.5	Confident	17 Å²	17	39 Å²	39	9%	0.089	22%	0.215	C	C	.	.	H	α-helix	trans	-53.3	-43.2	178.9	-162.9	74.8	0	0	0	113.2	Q116 M117 V118 T124 G162 R434	Q116-L120 PolarHBondContact O-N 3.14Å; M117-L120 WeakPolarHBondContact O-CB 3.41Å; M117-L120 PolarHBondContact O-N 3.29Å; M117-L120 HydrophobicContact SD-CD2 4.11Å; V118-L120 VanDerWaalsContact C-N 3.35Å; V118-L120 PolarHBondContact O-N 3.34Å; L120-T124 PolarHBondContact O-N 3.14Å; L120-T124 PolarHBondContact O-OG1 2.99Å; L120-G162 VanDerWaalsContact CA-O 3.29Å; L120-G162 WeakPolarHBondContact CA-O 3.41Å; L120-G162 WeakPolarHBondContact CD1-O 3.12Å; L120-R434 HydrophobicContact CD2-CG 4.31Å; L120-R434 HydrophobicContact CG-CG 4.13Å
121	L	85.2	Confident	80.9	Confident	52 Å²	52	41.1 Å²	41.1	27%	0.272	23%	0.233	S	C	.	.	H	α-helix	trans	-63.9	-53.3	177.9	175.9	64.7	0	0	0	112.1	M117 V118 G119 P125 I431 R434	M117-L121 WeakPolarHBondContact O-CB 3.39Å; M117-L121 PolarHBondContact O-N 2.88Å; V118-L121 PolarHBondContact O-N 3.13Å; G119-L121 VanDerWaalsContact C-N 3.29Å; G119-L121 PolarHBondContact O-N 3.08Å; L121-P125 WeakPolarHBondContact O-CD 3.24Å; L121-I431 HydrophobicContact CD1-CB 4.44Å; L121-I431 HydrophobicContact CD1-CG2 3.75Å; L121-I431 WeakPolarHBondContact CD1-O 3.21Å; L121-R434 HydrophobicContact CB-CB 3.96Å; L121-R434 HydrophobicContact CD1-CB 3.85Å
122	V	85.4	Confident	79	Confident	60 Å²	60	43 Å²	43	36%	0.364	24%	0.243	S	C	.	.	H	α-helix	trans	-69.8	-37.7	-175.9	178.5	0	0	0	0	111.1	V118 G119 P125 L126 F163	V118-V122 HydrophobicContact CG1-CG2 4.21Å; V118-V122 WeakPolarHBondContact O-CG2 3.16Å; V118-V122 PolarHBondContact O-N 2.9Å; G119-V122 PolarHBondContact O-N 3.26Å; V122-P125 WeakPolarHBondContact O-CD 3.49Å; V122-L126 HydrophobicContact CG1-CD1 3.8Å; V122-L126 WeakPolarHBondContact O-CG 3.14Å; V122-F163 HydrophobicContact CB-CD2 4.37Å; V122-F163 HydrophobicContact CB-CE2 4.48Å; V122-F163 HydrophobicContact CG1-CD2 4.24Å; V122-F163 HydrophobicContact CG1-CE2 3.9Å
123	G	82.5	Confident	77.1	Confident	0 Å²	0	47.5 Å²	47.5	0%	0	28%	0.275	C	S	.	.	H	α-helix	trans	-73.6	-27.1	-177.6	0	0	0	0	0	114.2	G119 L126 V127 F163	G119-G123 PolarHBondContact O-N 3.06Å; G123-L126 PolarHBondContact O-N 2.99Å; G123-V127 WeakPolarHBondContact O-CB 3.45Å; G123-V127 WeakPolarHBondContact O-CG2 3.44Å; G123-V127 PolarHBondContact O-N 3.34Å; G123-F163 CarbonylContact C-O 3.4Å; G123-F163 VanDerWaalsContact CA-CD2 3.49Å; G123-F163 WeakPolarHBondContact CA-O 3.32Å
124	T	79.9	Confident	75.4	Confident	6 Å²	6	53.1 Å²	53.1	4%	0.037	30%	0.296	C	S	.	.	H	α-helix	trans	-56.5	-54.4	179.9	-59.3	0	0	0	0	113.5	L120 A128 G166 S430	L120-T124 PolarHBondContact O-N 3.14Å; L120-T124 PolarHBondContact O-OG1 2.99Å; T124-A128 VanDerWaalsContact O-CB 3.29Å; T124-A128 WeakPolarHBondContact O-CB 3.4Å; T124-A128 PolarHBondContact O-N 3.48Å; T124-G166 PolarHBondContact OG1-O 3.01Å; T124-S430 VanDerWaalsContact CG2-OG 3.28Å; T124-S430 WeakPolarHBondContact CG2-OG 3.36Å
125	P	75.3	Confident	73.9	Confident	50 Å²	50	53 Å²	53	33%	0.325	30%	0.301	S	S	.	.	H	α-helix	trans	-71.7	-37.2	178	27.4	-34.4	0	0	0	113.2	L121 V122 Q129	L121-P125 WeakPolarHBondContact O-CD 3.24Å; V122-P125 WeakPolarHBondContact O-CD 3.49Å; P125-Q129 WeakPolarHBondContact O-CG 3.29Å; P125-Q129 PolarHBondContact O-N 3.38Å
126	L	79.1	Confident	72.2	Confident	73 Å²	73	59.2 Å²	59.2	38%	0.382	32%	0.321	S	S	.	.	H	α-helix	trans	-73.6	-48	-175.1	-65.8	178.3	0	0	0	111.9	V122 G123 A128 Q129 M130 F163	V122-L126 HydrophobicContact CG1-CD1 3.8Å; V122-L126 WeakPolarHBondContact O-CG 3.14Å; G123-L126 PolarHBondContact O-N 2.99Å; L126-A128 VanDerWaalsContact C-N 3.27Å; L126-A128 PolarHBondContact O-N 3.5Å; L126-Q129 WeakPolarHBondContact O-CA 3.42Å; L126-Q129 WeakPolarHBondContact O-CB 3.15Å; L126-Q129 PolarHBondContact O-N 2.8Å; L126-M130 WeakPolarHBondContact O-CG 3.44Å; L126-M130 PolarHBondContact O-N 2.83Å; L126-M130 VanDerWaalsContact O-N 3.09Å; L126-F163 HydrophobicContact CB-CZ 4.15Å; L126-F163 HydrophobicContact CD1-CE2 3.9Å; L126-F163 HydrophobicContact CD1-CZ 4.01Å
127	V	73	Confident	71	Confident	8 Å²	8	66.1 Å²	66.1	5%	0.048	35%	0.347	C	S	.	.	H	α-helix	trans	-66.4	-32.9	-179.8	175.9	0	0	0	0	111.1	G123 Q129 M130 S131 F163 F164	G123-V127 WeakPolarHBondContact O-CB 3.45Å; G123-V127 WeakPolarHBondContact O-CG2 3.44Å; G123-V127 PolarHBondContact O-N 3.34Å; V127-Q129 PolarHBondContact O-N 3.02Å; V127-M130 PolarHBondContact O-N 3.2Å; V127-S131 PolarHBondContact O-N 2.92Å; V127-F163 HydrophobicContact CG2-CD1 3.94Å; V127-F163 HydrophobicContact CG2-CE1 3.64Å; V127-F163 HydrophobicContact CG2-CZ 4.36Å; V127-F164 HydrophobicContact CG2-CD1 4.05Å
128	A	65.1	Low	70	Confident	57 Å²	57	66 Å²	66	47%	0.471	35%	0.347	S	S	.	.	H	α-helix	trans	-60.4	-29	171.9	0	0	0	0	0	112.9	T124 L126	T124-A128 VanDerWaalsContact O-CB 3.29Å; T124-A128 WeakPolarHBondContact O-CB 3.4Å; T124-A128 PolarHBondContact O-N 3.48Å; L126-A128 VanDerWaalsContact C-N 3.27Å; L126-A128 PolarHBondContact O-N 3.5Å
129	Q	67.8	Low	69	Low	160 Å²	160	63.6 Å²	63.6	75%	0.748	33%	0.332	S	S	*	.	H	α-helix	trans	-84.5	-23.2	174.1	-66.6	176.9	-17	0	0	112.9	P125 L126 V127	P125-Q129 WeakPolarHBondContact O-CG 3.29Å; P125-Q129 PolarHBondContact O-N 3.38Å; L126-Q129 WeakPolarHBondContact O-CA 3.42Å; L126-Q129 WeakPolarHBondContact O-CB 3.15Å; L126-Q129 PolarHBondContact O-N 2.8Å; V127-Q129 PolarHBondContact O-N 3.02Å
130	M	65.5	Low	68.2	Low	64 Å²	64	69.2 Å²	69.2	32%	0.315	36%	0.36	S	S	.	.			trans	-95.1	10.3	-173.2	-63.1	170.6	80.3	0	0	114.4	L126 V127 D132 S133 W134	L126-M130 WeakPolarHBondContact O-CG 3.44Å; L126-M130 PolarHBondContact O-N 2.83Å; L126-M130 VanDerWaalsContact O-N 3.09Å; V127-M130 PolarHBondContact O-N 3.2Å; M130-D132 PolarHBondContact O-N 3.13Å; M130-S133 PolarHBondContact O-N 3.49Å; M130-W134 HydrophobicContact CE-CB 4.33Å; M130-W134 HydrophobicContact CE-CD2 3.56Å; M130-W134 HydrophobicContact CE-CE3 3.15Å; M130-W134 HydrophobicContact CE-CG 4.09Å; M130-W134 HydrophobicContact CE-CH2 4.29Å; M130-W134 HydrophobicContact CE-CZ3 3.56Å
131	S	54.5	Low	67.8	Low	69 Å²	69	69 Å²	69	48%	0.483	36%	0.362	S	S	.	.	T	Hydrogen-bonded Turn	trans	-58.9	-14.5	-158.9	72.9	0	0	0	0	116.8	V127	V127-S131 PolarHBondContact O-N 2.92Å
132	D	49.4	Very low	67.4	Low	120 Å²	120	66.6 Å²	66.6	64%	0.642	35%	0.349	S	S	*	.	T	Hydrogen-bonded Turn	trans	-83.5	-12.8	-173.4	-75.8	2.1	0	0	0	115.3	M130	M130-D132 PolarHBondContact O-N 3.13Å
133	S	49	Very low	67.2	Low	96 Å²	96	65.5 Å²	65.5	67%	0.671	34%	0.343	S	S	*	.	T	Hydrogen-bonded Turn	trans	-147	-23	-174.4	62.9	0	0	0	0	118.9	M130	M130-S133 PolarHBondContact O-N 3.49Å
134	W	53.5	Low	67.3	Low	122 Å²	122	67.7 Å²	67.7	46%	0.462	36%	0.36	S	S	.	.			trans	-102.4	-5.7	-168.1	-87	32.3	0	0	0	116.1	M130 R136 R137 F164	M130-W134 HydrophobicContact CE-CB 4.33Å; M130-W134 HydrophobicContact CE-CD2 3.56Å; M130-W134 HydrophobicContact CE-CE3 3.15Å; M130-W134 HydrophobicContact CE-CG 4.09Å; M130-W134 HydrophobicContact CE-CH2 4.29Å; M130-W134 HydrophobicContact CE-CZ3 3.56Å; W134-R136 PolarHBondContact O-N 3.02Å; W134-R137 PolarHBondContact O-N 3.31Å; W134-F164 HydrophobicContact CB-CE1 4.4Å; W134-F164 HydrophobicContact CE3-CE1 4.33Å; W134-F164 HydrophobicContact CE3-CZ 4.33Å
135	G	56.3	Low	67.4	Low	28 Å²	28	67.4 Å²	67.4	29%	0.289	36%	0.359	S	S	.	.	T	Hydrogen-bonded Turn	trans	-63	-8.4	-172.4	0	0	0	0	0	117	P138	G135-P138 VanDerWaalsContact O-CD 3.23Å; G135-P138 WeakPolarHBondContact O-CD 3.35Å; G135-P138 WeakPolarHBondContact O-CG 3.29Å
136	R	57.1	Low	67.8	Low	180 Å²	180	65.2 Å²	65.2	68%	0.679	35%	0.345	S	S	*	.	T	Hydrogen-bonded Turn	trans	-87.2	-25.9	-177.9	-61.5	-176.7	-177	178.2	1.2	114.7	W134 L226	W134-R136 PolarHBondContact O-N 3.02Å; R136-L226 HydrophobicContact CB-CD1 4.16Å; R136-L226 HydrophobicContact CG-CD1 4.26Å; R136-L226 HydrophobicContact CG-CD2 4.22Å
137	R	63	Low	68.3	Low	155 Å²	155	68.9 Å²	68.9	59%	0.585	36%	0.358	S	S	*	.	H	α-helix	trans	-63.1	-29.8	179.9	-61.7	-178	-179.3	-126.1	0.3	117	W134 L139 A141 F164	W134-R137 PolarHBondContact O-N 3.31Å; R137-L139 VanDerWaalsContact C-N 3.29Å; R137-L139 PolarHBondContact O-N 2.9Å; R137-A141 PolarHBondContact O-N 3.5Å; R137-F164 HydrophobicContact CB-CE2 4.15Å; R137-F164 HydrophobicContact CB-CZ 4.11Å
138	P	65	Low	69.1	Low	5 Å²	5	69 Å²	69	3%	0.032	36%	0.359	C	S	.	.	H	α-helix	trans	-48.1	-49.5	177.4	3.6	-22.2	0	0	0	114.1	G135 A141 G142 F164 L168	G135-P138 VanDerWaalsContact O-CD 3.23Å; G135-P138 WeakPolarHBondContact O-CD 3.35Å; G135-P138 WeakPolarHBondContact O-CG 3.29Å; P138-A141 PolarHBondContact O-N 2.67Å; P138-G142 PolarHBondContact O-N 3.38Å; P138-F164 HydrophobicContact CB-CB 3.28Å; P138-F164 HydrophobicContact CB-CD2 4.3Å; P138-F164 HydrophobicContact CB-CG 4.04Å; P138-F164 VanDerWaalsContact CD-CG 3.48Å; P138-F164 HydrophobicContact CG-CB 3.46Å; P138-F164 VanDerWaalsContact CG-CB 3.46Å; P138-F164 HydrophobicContact CG-CG 4.03Å; P138-L168 HydrophobicContact CG-CD1 4.27Å
139	L	67.1	Low	70.2	Confident	14 Å²	14	74.1 Å²	74.1	7%	0.073	37%	0.373	C	S	.	.	H	α-helix	trans	-76.4	-34	-162	-66.1	165.9	0	0	0	110.4	T38 R137 G142 V143 G222 L226	T38-L139 HydrophobicContact CG2-CD2 3.82Å; R137-L139 VanDerWaalsContact C-N 3.29Å; R137-L139 PolarHBondContact O-N 2.9Å; L139-G142 PolarHBondContact O-N 3.35Å; L139-V143 WeakPolarHBondContact O-CG2 3.5Å; L139-V143 PolarHBondContact O-N 3.01Å; L139-G222 WeakPolarHBondContact CD1-O 3.5Å; L139-L226 HydrophobicContact CD1-CD1 3.47Å; L139-L226 VanDerWaalsContact CD1-CD1 3.47Å; L139-L226 HydrophobicContact CD1-CD2 4Å; L139-L226 HydrophobicContact CD1-CG 3.42Å; L139-L226 VanDerWaalsContact CD1-CG 3.42Å
140	I	73.6	Confident	71.2	Confident	117 Å²	117	73.9 Å²	73.9	60%	0.6	37%	0.365	S	S	*	.	H	α-helix	trans	-64.7	-45.2	172.6	-58.4	171.8	0	0	0	109.9	G142 V143 A144	I140-G142 VanDerWaalsContact C-N 3.29Å; I140-G142 PolarHBondContact O-N 2.88Å; I140-V143 PolarHBondContact O-N 3.42Å; I140-A144 WeakPolarHBondContact O-CB 3.2Å; I140-A144 PolarHBondContact O-N 2.87Å
141	A	76.8	Confident	72.4	Confident	14 Å²	14	74.4 Å²	74.4	12%	0.116	36%	0.364	C	S	.	.	H	α-helix	trans	-62.1	-37	177.6	0	0	0	0	0	112.2	R137 P138 G145 C157 L160	R137-A141 PolarHBondContact O-N 3.5Å; P138-A141 PolarHBondContact O-N 2.67Å; A141-G145 PolarHBondContact O-N 3.13Å; A141-C157 WeakPolarHBondContact O-CB 3.4Å; A141-C157 PolarHBondContact O-SG 2.89Å; A141-L160 HydrophobicContact CB-CB 3.79Å; A141-L160 HydrophobicContact CB-CD1 4.03Å
142	G	77.1	Confident	74.2	Confident	1 Å²	1	74 Å²	74	1%	0.01	35%	0.354	C	S	.	.	H	α-helix	trans	-68	-44.8	176.3	0	0	0	0	0	113.8	P138 L139 I140 A144 G145	P138-G142 PolarHBondContact O-N 3.38Å; L139-G142 PolarHBondContact O-N 3.35Å; I140-G142 VanDerWaalsContact C-N 3.29Å; I140-G142 PolarHBondContact O-N 2.88Å; G142-A144 VanDerWaalsContact C-N 3.32Å; G142-A144 PolarHBondContact O-N 3.47Å; G142-G145 PolarHBondContact O-N 3.21Å; G142-G145 VanDerWaalsContact O-N 3.16Å
143	V	81	Confident	76.2	Confident	37 Å²	37	71.7 Å²	71.7	22%	0.224	34%	0.344	C	S	.	.	H	α-helix	trans	-63.2	-40.5	175	173.5	0	0	0	0	110.9	L139 I140 G145 G146 F147 I216 N219	L139-V143 WeakPolarHBondContact O-CG2 3.5Å; L139-V143 PolarHBondContact O-N 3.01Å; I140-V143 PolarHBondContact O-N 3.42Å; V143-G145 PolarHBondContact O-N 2.92Å; V143-G146 PolarHBondContact O-N 2.95Å; V143-G146 VanDerWaalsContact O-N 3.16Å; V143-F147 HydrophobicContact CG1-CE2 4.24Å; V143-F147 WeakPolarHBondContact O-CD2 3.46Å; V143-I216 HydrophobicContact CG1-CG2 4.49Å; V143-N219 HydrophobicContact CG2-CB 3.84Å
144	A	84.4	Confident	78.3	Confident	45 Å²	45	67.2 Å²	67.2	37%	0.372	31%	0.313	S	S	.	.	H	α-helix	trans	-59.4	-31.1	175.6	0	0	0	0	0	112.7	I140 G142 G146 F147	I140-A144 WeakPolarHBondContact O-CB 3.2Å; I140-A144 PolarHBondContact O-N 2.87Å; G142-A144 VanDerWaalsContact C-N 3.32Å; G142-A144 PolarHBondContact O-N 3.47Å; A144-G146 PolarHBondContact O-N 3.19Å; A144-F147 PolarHBondContact O-N 2.93Å; A144-F147 VanDerWaalsContact O-N 3.09Å
145	G	82.1	Confident	80.2	Confident	1 Å²	1	61.6 Å²	61.6	1%	0.01	29%	0.292	C	S	.	.	H	α-helix	trans	-55.9	-29.7	175.7	0	0	0	0	0	114.2	A141 G142 V143 F147 T148 L154	A141-G145 PolarHBondContact O-N 3.13Å; G142-G145 PolarHBondContact O-N 3.21Å; G142-G145 VanDerWaalsContact O-N 3.16Å; V143-G145 PolarHBondContact O-N 2.92Å; G145-F147 VanDerWaalsContact C-N 3.29Å; G145-F147 PolarHBondContact O-N 3Å; G145-T148 PolarHBondContact O-OG1 3.26Å; G145-L154 WeakPolarHBondContact O-CD1 3.4Å
146	G	83.4	Confident	81.9	Confident	3 Å²	3	64.1 Å²	64.1	3%	0.031	30%	0.302	C	S	.	.	T	Hydrogen-bonded Turn	trans	-74.2	-18.1	178.8	0	0	0	0	0	115	V143 A144 R212	V143-G146 PolarHBondContact O-N 2.95Å; V143-G146 VanDerWaalsContact O-N 3.16Å; A144-G146 PolarHBondContact O-N 3.19Å; G146-R212 WeakPolarHBondContact O-CB 3.48Å; G146-R212 WeakPolarHBondContact O-CG 3.41Å
147	F	89.5	Confident	83.5	Confident	151 Å²	151	56.2 Å²	56.2	66%	0.662	27%	0.274	S	S	*	.	T	Hydrogen-bonded Turn	trans	-97.3	-0.2	-179.4	-60.6	-78.2	0	0	0	112.8	V143 A144 G145 I216	V143-F147 HydrophobicContact CG1-CE2 4.24Å; V143-F147 WeakPolarHBondContact O-CD2 3.46Å; A144-F147 PolarHBondContact O-N 2.93Å; A144-F147 VanDerWaalsContact O-N 3.09Å; G145-F147 VanDerWaalsContact C-N 3.29Å; G145-F147 PolarHBondContact O-N 3Å; F147-I216 HydrophobicContact CE1-CD1 4.32Å; F147-I216 HydrophobicContact CE2-CD1 4.01Å; F147-I216 HydrophobicContact CE2-CG1 4.37Å; F147-I216 HydrophobicContact CZ-CD1 3.91Å
148	T	89.2	Confident	84.8	Confident	9 Å²	9	49.1 Å²	49.1	6%	0.055	25%	0.248	C	C	.	.			trans	-72.8	135.1	-176.7	62.3	0	0	0	0	111.3	G145 V153 L154	G145-T148 PolarHBondContact O-OG1 3.26Å; T148-V153 HydrophobicContact CG2-CB 3.99Å; T148-V153 HydrophobicContact CG2-CG1 3.56Å; T148-L154 WeakPolarHBondContact OG1-CB 3.16Å
149	Q	88.6	Confident	86.1	Confident	166 Å²	166	52 Å²	52	78%	0.776	26%	0.26	S	S	*	.	S	Bend	trans	-96.7	-5.1	175.3	-62.5	-176.5	-5	0	0	113.3
150	R	89.8	Confident	87.1	Confident	154 Å²	154	54.3 Å²	54.3	58%	0.581	27%	0.272	S	S	*	.	S	Bend	trans	-130.4	136.3	-174.7	-80	-168	68.9	170.8	7.7	110.3	E152 V153 L154	R150-E152 WeakPolarHBondContact CB-OE2 3.29Å; R150-E152 IonicContact CZ-OE1 3.38Å; R150-E152 IonicContact CZ-OE2 3.74Å; R150-E152 IonicContact NE-OE1 3.31Å; R150-E152 IonicContact NE-OE2 2.61Å; R150-E152 PolarHBondContact NE-OE2 2.68Å; R150-E152 VanDerWaalsContact NH2-CD 3.28Å; R150-E152 IonicContact NH2-OE1 3.79Å; R150-E152 PolarHBondContact NH2-OE1 3.16Å; R150-E152 IonicContact NH2-OE2 3.29Å; R150-E152 PolarHBondContact O-N 3.37Å; R150-V153 HydrophobicContact CB-CG2 4.04Å; R150-V153 PolarHBondContact O-N 2.66Å; R150-L154 PolarHBondContact O-N 3.04Å; R150-L154 VanDerWaalsContact O-N 3.13Å
151	W	90.2	Very high	87.8	Confident	76 Å²	76	49.2 Å²	49.2	29%	0.288	25%	0.247	S	C	.	.	H	α-helix	trans	-65	-29.3	-178	70.4	-94.5	0	0	0	112.8	W99 I108 M112 V153 L154 A155	W99-W151 HydrophobicContact CD2-CB 4.24Å; W99-W151 HydrophobicContact CE3-CB 3.34Å; W99-W151 HydrophobicContact CE3-CG 4.49Å; W99-W151 VanDerWaalsContact CH2-CA 3.48Å; W99-W151 HydrophobicContact CH2-CB 3.97Å; W99-W151 HydrophobicContact CZ3-CB 3.19Å; I108-W151 HydrophobicContact CD1-CZ2 4.26Å; I108-W151 HydrophobicContact CG2-CD2 3.61Å; I108-W151 HydrophobicContact CG2-CE3 3.44Å; I108-W151 VanDerWaalsContact CG2-CE3 3.44Å; I108-W151 HydrophobicContact CG2-CG 4.18Å; I108-W151 HydrophobicContact CG2-CH2 4.26Å; I108-W151 HydrophobicContact CG2-CZ2 4.41Å; I108-W151 HydrophobicContact CG2-CZ3 3.79Å; M112-W151 HydrophobicContact CG-CE3 4.42Å; M112-W151 HydrophobicContact SD-CB 4.35Å; W151-V153 VanDerWaalsContact C-N 3.35Å; W151-L154 PolarHBondContact O-N 3Å; W151-A155 VanDerWaalsContact O-CB 3.32Å; W151-A155 WeakPolarHBondContact O-CB 3.41Å; W151-A155 PolarHBondContact O-N 3.32Å
152	E	92.1	Very high	88.3	Confident	61 Å²	61	48.8 Å²	48.8	29%	0.285	24%	0.244	S	C	.	.	H	α-helix	trans	-67.1	-38.2	177.8	-54.4	91.4	150.7	0	0	111.6	R150 A155 T156	R150-E152 WeakPolarHBondContact CB-OE2 3.29Å; R150-E152 IonicContact CZ-OE1 3.38Å; R150-E152 IonicContact CZ-OE2 3.74Å; R150-E152 IonicContact NE-OE1 3.31Å; R150-E152 IonicContact NE-OE2 2.61Å; R150-E152 PolarHBondContact NE-OE2 2.68Å; R150-E152 VanDerWaalsContact NH2-CD 3.28Å; R150-E152 IonicContact NH2-OE1 3.79Å; R150-E152 PolarHBondContact NH2-OE1 3.16Å; R150-E152 IonicContact NH2-OE2 3.29Å; R150-E152 PolarHBondContact O-N 3.37Å; E152-A155 PolarHBondContact O-N 3.45Å; E152-T156 PolarHBondContact O-N 2.62Å; E152-T156 PolarHBondContact O-OG1 3.45Å
153	V	92.3	Very high	88.6	Confident	71 Å²	71	50.1 Å²	50.1	43%	0.43	25%	0.249	S	C	.	.	H	α-helix	trans	-71	-42.2	176.7	-172.9	0	0	0	0	109.7	T148 R150 W151 A155 T156 C157	T148-V153 HydrophobicContact CG2-CB 3.99Å; T148-V153 HydrophobicContact CG2-CG1 3.56Å; R150-V153 HydrophobicContact CB-CG2 4.04Å; R150-V153 PolarHBondContact O-N 2.66Å; W151-V153 VanDerWaalsContact C-N 3.35Å; V153-A155 VanDerWaalsContact C-N 3.35Å; V153-A155 PolarHBondContact O-N 2.9Å; V153-T156 WeakPolarHBondContact O-CB 3.35Å; V153-T156 PolarHBondContact O-N 2.85Å; V153-C157 PolarHBondContact O-N 3.46Å
154	L	92.9	Very high	88.6	Confident	1 Å²	1	49 Å²	49	1%	0.005	24%	0.242	C	C	.	.	H	α-helix	trans	-59.8	-45.3	173.6	-178.5	53.9	0	0	0	111.5	I95 W99 M112 G145 T148 R150 W151 T156 C157 M158 W211	I95-L154 HydrophobicContact CD1-CD2 3.75Å; I95-L154 HydrophobicContact CG1-CD2 4.38Å; W99-L154 HydrophobicContact CH2-CB 3.96Å; W99-L154 HydrophobicContact CH2-CD2 3.61Å; W99-L154 HydrophobicContact CH2-CG 4.45Å; W99-L154 HydrophobicContact CZ3-CB 4.46Å; W99-L154 HydrophobicContact CZ3-CD2 3.85Å; M112-L154 HydrophobicContact CE-CB 4.16Å; M112-L154 HydrophobicContact CE-CD2 3.61Å; M112-L154 HydrophobicContact CE-CG 3.71Å; G145-L154 WeakPolarHBondContact O-CD1 3.4Å; T148-L154 WeakPolarHBondContact OG1-CB 3.16Å; R150-L154 PolarHBondContact O-N 3.04Å; R150-L154 VanDerWaalsContact O-N 3.13Å; W151-L154 PolarHBondContact O-N 3Å; L154-T156 VanDerWaalsContact C-N 3.27Å; L154-T156 PolarHBondContact O-N 2.79Å; L154-C157 WeakPolarHBondContact O-CB 3.33Å; L154-C157 PolarHBondContact O-N 3.48Å; L154-M158 HydrophobicContact CD1-CG 4.19Å; L154-M158 HydrophobicContact CD1-SD 4.38Å; L154-M158 HydrophobicContact CG-CG 4.4Å; L154-M158 HydrophobicContact CG-SD 4.08Å; L154-M158 WeakPolarHBondContact O-CB 3.29Å; L154-M158 VanDerWaalsContact O-CG 3.28Å; L154-M158 WeakPolarHBondContact O-CG 3.16Å; L154-M158 PolarHBondContact O-N 3.34Å; L154-W211 HydrophobicContact CD1-CZ3 4.42Å; L154-W211 HydrophobicContact CD2-CE3 4.25Å; L154-W211 HydrophobicContact CD2-CH2 4.05Å; L154-W211 HydrophobicContact CD2-CZ3 3.64Å
155	A	92.3	Very high	88.3	Confident	4 Å²	4	47.6 Å²	47.6	3%	0.033	23%	0.231	C	C	.	.	H	α-helix	trans	-59.1	-39.8	176.6	0	0	0	0	0	111.7	M112 I115 W151 E152 V153 M158 F159	M112-A155 HydrophobicContact CG-CB 4.08Å; I115-A155 HydrophobicContact CD1-CB 4.04Å; I115-A155 WeakPolarHBondContact CG2-O 3.43Å; W151-A155 VanDerWaalsContact O-CB 3.32Å; W151-A155 WeakPolarHBondContact O-CB 3.41Å; W151-A155 PolarHBondContact O-N 3.32Å; E152-A155 PolarHBondContact O-N 3.45Å; V153-A155 VanDerWaalsContact C-N 3.35Å; V153-A155 PolarHBondContact O-N 2.9Å; A155-M158 PolarHBondContact O-N 3.49Å; A155-F159 PolarHBondContact O-N 2.88Å
156	T	92	Very high	87.9	Confident	81 Å²	81	47.6 Å²	47.6	50%	0.497	23%	0.231	S	C	.	.	H	α-helix	trans	-65.8	-44.4	175.1	-55.4	0	0	0	0	111.6	E152 V153 L154 M158 F159 L160	E152-T156 PolarHBondContact O-N 2.62Å; E152-T156 PolarHBondContact O-OG1 3.45Å; V153-T156 WeakPolarHBondContact O-CB 3.35Å; V153-T156 PolarHBondContact O-N 2.85Å; L154-T156 VanDerWaalsContact C-N 3.27Å; L154-T156 PolarHBondContact O-N 2.79Å; T156-M158 VanDerWaalsContact C-N 3.32Å; T156-M158 PolarHBondContact O-N 2.94Å; T156-F159 WeakPolarHBondContact O-CB 3.47Å; T156-F159 PolarHBondContact O-N 3.35Å; T156-L160 WeakPolarHBondContact O-CG 3.3Å; T156-L160 PolarHBondContact O-N 3.43Å
157	C	91.4	Very high	87.1	Confident	14 Å²	14	47.5 Å²	47.5	10%	0.095	23%	0.23	C	C	.	.	H	α-helix	trans	-59.3	-43.3	173.1	-75.7	0	0	0	0	111.6	A141 V153 L154 L160 T161	A141-C157 WeakPolarHBondContact O-CB 3.4Å; A141-C157 PolarHBondContact O-SG 2.89Å; V153-C157 PolarHBondContact O-N 3.46Å; L154-C157 WeakPolarHBondContact O-CB 3.33Å; L154-C157 PolarHBondContact O-N 3.48Å; C157-L160 PolarHBondContact O-N 3.26Å; C157-T161 WeakPolarHBondContact O-CG2 3.44Å; C157-T161 PolarHBondContact O-N 2.82Å; C157-T161 PolarHBondContact O-OG1 3.45Å
158	M	90.7	Very high	86.2	Confident	6 Å²	6	42.5 Å²	42.5	3%	0.03	21%	0.21	C	C	.	.	H	α-helix	trans	-65.1	-38.3	176.7	-70.9	176.9	72	0	0	112.6	Y45 M46 M112 Q116 L154 A155 T156 L160 T161 G162	Y45-M158 HydrophobicContact CD1-CE 4.1Å; Y45-M158 HydrophobicContact CE1-CE 4.21Å; Y45-M158 HydrophobicContact CE1-SD 4.18Å; M46-M158 HydrophobicContact CG-CE 3.65Å; M46-M158 HydrophobicContact SD-CE 3.65Å; M46-M158 HydrophobicContact SD-SD 4.39Å; M112-M158 HydrophobicContact CB-SD 4.47Å; M112-M158 HydrophobicContact CE-SD 3.75Å; Q116-M158 HydrophobicContact CB-CB 4.2Å; Q116-M158 HydrophobicContact CB-CE 4.12Å; Q116-M158 HydrophobicContact CG-CB 4.36Å; Q116-M158 HydrophobicContact CG-CE 4.42Å; L154-M158 HydrophobicContact CD1-CG 4.19Å; L154-M158 HydrophobicContact CD1-SD 4.38Å; L154-M158 HydrophobicContact CG-CG 4.4Å; L154-M158 HydrophobicContact CG-SD 4.08Å; L154-M158 WeakPolarHBondContact O-CB 3.29Å; L154-M158 VanDerWaalsContact O-CG 3.28Å; L154-M158 WeakPolarHBondContact O-CG 3.16Å; L154-M158 PolarHBondContact O-N 3.34Å; A155-M158 PolarHBondContact O-N 3.49Å; T156-M158 VanDerWaalsContact C-N 3.32Å; T156-M158 PolarHBondContact O-N 2.94Å; M158-L160 VanDerWaalsContact C-N 3.34Å; M158-T161 WeakPolarHBondContact CA-OG1 3.29Å; M158-T161 PolarHBondContact O-OG1 3.25Å; M158-G162 PolarHBondContact O-N 3.28Å
159	F	91	Very high	85.2	Confident	65 Å²	65	43.3 Å²	43.3	29%	0.285	22%	0.22	S	C	.	.	H	α-helix	trans	-58.6	-47.8	171.6	178.2	-96.9	0	0	0	110.8	I115 V118 G119 A155 T156 G162 F163	I115-F159 HydrophobicContact CG2-CB 3.62Å; I115-F159 HydrophobicContact CG2-CD2 4.14Å; I115-F159 HydrophobicContact CG2-CG 4.34Å; I115-F159 WeakPolarHBondContact O-CD2 3.44Å; V118-F159 HydrophobicContact CG1-CE2 4.27Å; G119-F159 VanDerWaalsContact CA-CE2 3.48Å; A155-F159 PolarHBondContact O-N 2.88Å; T156-F159 WeakPolarHBondContact O-CB 3.47Å; T156-F159 PolarHBondContact O-N 3.35Å; F159-G162 PolarHBondContact O-N 3.3Å; F159-F163 HydrophobicContact CE1-CB 4.46Å; F159-F163 HydrophobicContact CE1-CD2 4.39Å; F159-F163 HydrophobicContact CZ-CD2 4.33Å; F159-F163 VanDerWaalsContact O-CB 3.26Å; F159-F163 WeakPolarHBondContact O-CB 3.28Å; F159-F163 PolarHBondContact O-N 2.68Å
160	L	89.6	Confident	84.2	Confident	63 Å²	63	38.1 Å²	38.1	33%	0.33	20%	0.201	S	C	.	.	H	α-helix	trans	-65.9	-43.2	-179.3	-67.2	173.1	0	0	0	111.8	A141 T156 C157 M158 G162 F163 F164	A141-L160 HydrophobicContact CB-CB 3.79Å; A141-L160 HydrophobicContact CB-CD1 4.03Å; T156-L160 WeakPolarHBondContact O-CG 3.3Å; T156-L160 PolarHBondContact O-N 3.43Å; C157-L160 PolarHBondContact O-N 3.26Å; M158-L160 VanDerWaalsContact C-N 3.34Å; L160-G162 VanDerWaalsContact C-N 3.32Å; L160-G162 PolarHBondContact O-N 3.08Å; L160-F163 PolarHBondContact O-N 3.25Å; L160-F164 HydrophobicContact CD2-CE2 4.34Å; L160-F164 WeakPolarHBondContact O-CD2 3.03Å; L160-F164 PolarHBondContact O-N 3.3Å
161	T	86.8	Confident	83.2	Confident	11 Å²	11	33.7 Å²	33.7	7%	0.067	19%	0.188	C	C	.	.	H	α-helix	trans	-62.9	-40.9	175	57.4	0	0	0	0	111.6	C157 M158 G165	C157-T161 WeakPolarHBondContact O-CG2 3.44Å; C157-T161 PolarHBondContact O-N 2.82Å; C157-T161 PolarHBondContact O-OG1 3.45Å; M158-T161 WeakPolarHBondContact CA-OG1 3.29Å; M158-T161 PolarHBondContact O-OG1 3.25Å; T161-G165 WeakPolarHBondContact O-CA 3.36Å; T161-G165 PolarHBondContact O-N 3.45Å
162	G	87.1	Confident	82.6	Confident	5 Å²	5	30.5 Å²	30.5	5%	0.052	18%	0.176	C	C	.	.	H	α-helix	trans	-60	-54.4	173	0	0	0	0	0	111.7	L120 M158 F159 L160 F164 G165 G166	L120-G162 VanDerWaalsContact CA-O 3.29Å; L120-G162 WeakPolarHBondContact CA-O 3.41Å; L120-G162 WeakPolarHBondContact CD1-O 3.12Å; M158-G162 PolarHBondContact O-N 3.28Å; F159-G162 PolarHBondContact O-N 3.3Å; L160-G162 VanDerWaalsContact C-N 3.32Å; L160-G162 PolarHBondContact O-N 3.08Å; G162-F164 PolarHBondContact O-N 3.38Å; G162-G165 PolarHBondContact O-N 3.31Å; G162-G166 PolarHBondContact O-N 3.06Å
163	F	85.2	Confident	81.6	Confident	28 Å²	28	28.3 Å²	28.3	12%	0.123	17%	0.171	C	C	.	.	H	α-helix	trans	-50.6	-56.7	179.8	-177.7	-86.6	0	0	0	112.1	G119 V122 G123 L126 V127 F159 L160	G119-F163 VanDerWaalsContact C-CA 3.45Å; G119-F163 VanDerWaalsContact C-N 3.3Å; G119-F163 WeakPolarHBondContact O-CA 3.37Å; V122-F163 HydrophobicContact CB-CD2 4.37Å; V122-F163 HydrophobicContact CB-CE2 4.48Å; V122-F163 HydrophobicContact CG1-CD2 4.24Å; V122-F163 HydrophobicContact CG1-CE2 3.9Å; G123-F163 CarbonylContact C-O 3.4Å; G123-F163 VanDerWaalsContact CA-CD2 3.49Å; G123-F163 WeakPolarHBondContact CA-O 3.32Å; L126-F163 HydrophobicContact CB-CZ 4.15Å; L126-F163 HydrophobicContact CD1-CE2 3.9Å; L126-F163 HydrophobicContact CD1-CZ 4.01Å; V127-F163 HydrophobicContact CG2-CD1 3.94Å; V127-F163 HydrophobicContact CG2-CE1 3.64Å; V127-F163 HydrophobicContact CG2-CZ 4.36Å; F159-F163 HydrophobicContact CE1-CB 4.46Å; F159-F163 HydrophobicContact CE1-CD2 4.39Å; F159-F163 HydrophobicContact CZ-CD2 4.33Å; F159-F163 VanDerWaalsContact O-CB 3.26Å; F159-F163 WeakPolarHBondContact O-CB 3.28Å; F159-F163 PolarHBondContact O-N 2.68Å; L160-F163 PolarHBondContact O-N 3.25Å
164	F	80.9	Confident	80.7	Confident	15 Å²	15	28.3 Å²	28.3	7%	0.066	17%	0.171	C	C	.	.	H	α-helix	trans	-75.2	-34.2	-178.1	-72.1	-68.3	0	0	0	112.9	V127 W134 R137 P138 L160 G162 G166 L168	V127-F164 HydrophobicContact CG2-CD1 4.05Å; W134-F164 HydrophobicContact CB-CE1 4.4Å; W134-F164 HydrophobicContact CE3-CE1 4.33Å; W134-F164 HydrophobicContact CE3-CZ 4.33Å; R137-F164 HydrophobicContact CB-CE2 4.15Å; R137-F164 HydrophobicContact CB-CZ 4.11Å; P138-F164 HydrophobicContact CB-CB 3.28Å; P138-F164 HydrophobicContact CB-CD2 4.3Å; P138-F164 HydrophobicContact CB-CG 4.04Å; P138-F164 VanDerWaalsContact CD-CG 3.48Å; P138-F164 HydrophobicContact CG-CB 3.46Å; P138-F164 VanDerWaalsContact CG-CB 3.46Å; P138-F164 HydrophobicContact CG-CG 4.03Å; L160-F164 HydrophobicContact CD2-CE2 4.34Å; L160-F164 WeakPolarHBondContact O-CD2 3.03Å; L160-F164 PolarHBondContact O-N 3.3Å; G162-F164 PolarHBondContact O-N 3.38Å; F164-G166 VanDerWaalsContact C-N 3.3Å; F164-G166 PolarHBondContact O-N 2.97Å; F164-L168 WeakPolarHBondContact O-CG 3.41Å; F164-L168 PolarHBondContact O-N 3.36Å
165	G	78.2	Confident	80	Confident	15 Å²	15	29 Å²	29	16%	0.155	17%	0.173	C	C	.	.	H	α-helix	trans	-65	-31.1	176.4	0	0	0	0	0	113.7	T161 G162 L168 G169	T161-G165 WeakPolarHBondContact O-CA 3.36Å; T161-G165 PolarHBondContact O-N 3.45Å; G162-G165 PolarHBondContact O-N 3.31Å; G165-L168 PolarHBondContact O-N 2.77Å; G165-G169 PolarHBondContact O-N 3.27Å
166	G	72	Confident	79.3	Confident	0 Å²	0	29 Å²	29	0%	0	17%	0.173	C	C	.	.	H	α-helix	trans	-62.4	-44.3	-179.3	0	0	0	0	0	113.1	T124 G162 F164 P170	T124-G166 PolarHBondContact OG1-O 3.01Å; G162-G166 PolarHBondContact O-N 3.06Å; F164-G166 VanDerWaalsContact C-N 3.3Å; F164-G166 PolarHBondContact O-N 2.97Å; G166-P170 VanDerWaalsContact O-CD 3.32Å; G166-P170 WeakPolarHBondContact O-CD 3.48Å
167	G	67.5	Low	78.5	Confident	1 Å²	1	27 Å²	27	1%	0.01	16%	0.16	C	C	.	.	H	α-helix	trans	-73.1	-32.8	176.7	0	0	0	0	0	113.8	G169 P170 I171	G167-G169 VanDerWaalsContact C-N 3.33Å; G167-G169 PolarHBondContact O-N 2.98Å; G167-P170 WeakPolarHBondContact O-CD 3.42Å; G167-I171 WeakPolarHBondContact O-CD1 3.29Å; G167-I171 WeakPolarHBondContact O-CG1 3.25Å
168	L	71.2	Confident	77.6	Confident	46 Å²	46	27.8 Å²	27.8	24%	0.241	16%	0.163	C	C	.	.	H	α-helix	trans	-62.9	-37.1	-178.5	-74.2	177.1	0	0	0	112.7	P138 F164 G165 I171 I172	P138-L168 HydrophobicContact CG-CD1 4.27Å; F164-L168 WeakPolarHBondContact O-CG 3.41Å; F164-L168 PolarHBondContact O-N 3.36Å; G165-L168 PolarHBondContact O-N 2.77Å; L168-I171 PolarHBondContact O-N 2.99Å; L168-I172 HydrophobicContact CB-CD1 3.83Å; L168-I172 HydrophobicContact CD2-CD1 4.34Å; L168-I172 VanDerWaalsContact O-CB 3.25Å; L168-I172 WeakPolarHBondContact O-CB 3.29Å; L168-I172 VanDerWaalsContact O-CD1 3.26Å; L168-I172 WeakPolarHBondContact O-CD1 3.35Å; L168-I172 WeakPolarHBondContact O-CG1 3.45Å; L168-I172 PolarHBondContact O-N 3.13Å
169	G	68.7	Low	76.8	Confident	27 Å²	27	27.5 Å²	27.5	28%	0.278	16%	0.161	S	C	.	.	H	α-helix	trans	-53.8	-61.3	-177.3	0	0	0	0	0	114	G165 G167 I171 I172 G173	G165-G169 PolarHBondContact O-N 3.27Å; G167-G169 VanDerWaalsContact C-N 3.33Å; G167-G169 PolarHBondContact O-N 2.98Å; G169-I171 PolarHBondContact O-N 3.2Å; G169-I172 PolarHBondContact O-N 2.72Å; G169-G173 PolarHBondContact O-N 3.45Å; G169-G173 VanDerWaalsContact O-N 3.12Å
170	P	65.6	Low	75.9	Confident	57 Å²	57	24.8 Å²	24.8	37%	0.37	15%	0.15	S	C	.	.	H	α-helix	trans	-60.1	-42.3	177.1	-24.9	34.1	0	0	0	113.6	G166 G167 I172 G173 V174	G166-P170 VanDerWaalsContact O-CD 3.32Å; G166-P170 WeakPolarHBondContact O-CD 3.48Å; G167-P170 WeakPolarHBondContact O-CD 3.42Å; P170-I172 VanDerWaalsContact C-N 3.3Å; P170-I172 PolarHBondContact O-N 3.41Å; P170-G173 PolarHBondContact O-N 3.45Å; P170-V174 WeakPolarHBondContact O-CG2 3.45Å; P170-V174 PolarHBondContact O-N 3.39Å
171	I	70.4	Confident	74.9	Confident	61 Å²	61	24.3 Å²	24.3	31%	0.313	15%	0.147	S	C	.	.	H	α-helix	trans	-58.5	-45.3	-179.2	-66.6	169.6	0	0	0	110.5	G167 L168 G169 V174 Y175	G167-I171 WeakPolarHBondContact O-CD1 3.29Å; G167-I171 WeakPolarHBondContact O-CG1 3.25Å; L168-I171 PolarHBondContact O-N 2.99Å; G169-I171 PolarHBondContact O-N 3.2Å; I171-V174 PolarHBondContact O-N 2.95Å; I171-Y175 WeakPolarHBondContact O-CB 3.04Å; I171-Y175 PolarHBondContact O-N 3.44Å
172	I	76.3	Confident	73.9	Confident	8 Å²	8	30 Å²	30	4%	0.041	17%	0.173	C	C	.	.	H	α-helix	trans	-72.8	-35.7	-176.3	-68.6	167	0	0	0	111.3	F31 F32 C35 L168 G169 P170 Y175 L176	F31-I172 HydrophobicContact CE1-CG1 4Å; F31-I172 HydrophobicContact CE1-CG2 4.36Å; F31-I172 HydrophobicContact CZ-CD1 4.22Å; F31-I172 HydrophobicContact CZ-CG1 4.07Å; F32-I172 HydrophobicContact CB-CG2 4.03Å; F32-I172 HydrophobicContact CD2-CG2 3.35Å; F32-I172 HydrophobicContact CE2-CG2 4.1Å; F32-I172 HydrophobicContact CG-CG2 4.05Å; C35-I172 HydrophobicContact CB-CD1 3.37Å; C35-I172 HydrophobicContact CB-CG2 4.3Å; C35-I172 WeakPolarHBondContact SG-CD1 3.47Å; L168-I172 HydrophobicContact CB-CD1 3.83Å; L168-I172 HydrophobicContact CD2-CD1 4.34Å; L168-I172 VanDerWaalsContact O-CB 3.25Å; L168-I172 WeakPolarHBondContact O-CB 3.29Å; L168-I172 VanDerWaalsContact O-CD1 3.26Å; L168-I172 WeakPolarHBondContact O-CD1 3.35Å; L168-I172 WeakPolarHBondContact O-CG1 3.45Å; L168-I172 PolarHBondContact O-N 3.13Å; G169-I172 PolarHBondContact O-N 2.72Å; P170-I172 VanDerWaalsContact C-N 3.3Å; P170-I172 PolarHBondContact O-N 3.41Å; I172-Y175 PolarHBondContact O-N 2.89Å; I172-L176 WeakPolarHBondContact O-CB 3.28Å; I172-L176 PolarHBondContact O-N 3.33Å
173	G	72.9	Confident	72.9	Confident	16 Å²	16	38.3 Å²	38.3	17%	0.165	21%	0.207	C	C	.	.	H	α-helix	trans	-61.4	-44.3	171.5	0	0	0	0	0	112.7	G169 P170 L176 V177	G169-G173 PolarHBondContact O-N 3.45Å; G169-G173 VanDerWaalsContact O-N 3.12Å; P170-G173 PolarHBondContact O-N 3.45Å; G173-L176 PolarHBondContact O-N 3.2Å; G173-V177 VanDerWaalsContact O-CG2 3.3Å; G173-V177 WeakPolarHBondContact O-CG2 3.02Å; G173-V177 PolarHBondContact O-N 3.17Å; G173-V177 VanDerWaalsContact O-N 3.08Å
174	V	72.2	Confident	72.1	Confident	71 Å²	71	40.6 Å²	40.6	43%	0.43	22%	0.218	S	C	.	.	H	α-helix	trans	-63.5	-48.5	175.4	172.7	0	0	0	0	110.6	P170 I171 L176 V177 E178	P170-V174 WeakPolarHBondContact O-CG2 3.45Å; P170-V174 PolarHBondContact O-N 3.39Å; I171-V174 PolarHBondContact O-N 2.95Å; V174-L176 VanDerWaalsContact C-N 3.26Å; V174-L176 PolarHBondContact O-N 3.32Å; V174-V177 PolarHBondContact O-N 3.39Å; V174-V177 VanDerWaalsContact O-N 3.12Å; V174-E178 HydrophobicContact CG1-CG 4.17Å; V174-E178 WeakPolarHBondContact CG1-OE1 3.26Å; V174-E178 WeakPolarHBondContact O-CG 3.15Å; V174-E178 PolarHBondContact O-N 2.91Å
175	Y	77.4	Confident	71.7	Confident	14 Å²	14	41.9 Å²	41.9	6%	0.055	22%	0.223	C	C	.	.	H	α-helix	trans	-55.8	-41.2	177.7	-179.1	-94.9	0	0	0	112.2	A28 F31 I171 I172 N179 I229 L232 K233	A28-Y175 HydrophobicContact CB-CE1 3.94Å; F31-Y175 HydrophobicContact CD1-CD1 4.2Å; F31-Y175 HydrophobicContact CD1-CE1 4.22Å; F31-Y175 HydrophobicContact CE1-CD1 4.31Å; I171-Y175 WeakPolarHBondContact O-CB 3.04Å; I171-Y175 PolarHBondContact O-N 3.44Å; I172-Y175 PolarHBondContact O-N 2.89Å; Y175-N179 WeakPolarHBondContact CE2-ND2 3.27Å; Y175-N179 WeakPolarHBondContact O-CB 3.36Å; Y175-N179 PolarHBondContact O-N 3.23Å; Y175-N179 PolarHBondContact O-ND2 3.39Å; Y175-I229 HydrophobicContact CE1-CD1 4.41Å; Y175-I229 HydrophobicContact CE2-CD1 4.4Å; Y175-L232 HydrophobicContact CE1-CD1 4.27Å; Y175-L232 WeakPolarHBondContact OH-CB 3.33Å; Y175-K233 PolarHBondContact OH-O 2.96Å
176	L	78.1	Confident	71.2	Confident	4 Å²	4	42.6 Å²	42.6	2%	0.021	22%	0.223	C	C	.	.	H	α-helix	trans	-63.8	-49.1	176.4	-172.7	71.5	0	0	0	111.8	Y29 F32 I172 G173 V174 E178 N179 I180 F189	Y29-L176 HydrophobicContact CD2-CD1 4.06Å; F32-L176 HydrophobicContact CB-CB 4.47Å; F32-L176 HydrophobicContact CB-CD1 3.88Å; F32-L176 HydrophobicContact CB-CD2 4.43Å; F32-L176 HydrophobicContact CB-CG 4.49Å; F32-L176 HydrophobicContact CD1-CD2 3.79Å; F32-L176 HydrophobicContact CD2-CB 3.76Å; F32-L176 HydrophobicContact CD2-CD1 4.45Å; F32-L176 HydrophobicContact CD2-CD2 3.7Å; F32-L176 HydrophobicContact CD2-CG 4.16Å; F32-L176 HydrophobicContact CE1-CD2 3.92Å; F32-L176 HydrophobicContact CE2-CB 4.35Å; F32-L176 HydrophobicContact CE2-CD2 3.89Å; F32-L176 HydrophobicContact CG-CB 4.22Å; F32-L176 HydrophobicContact CG-CD1 4.07Å; F32-L176 HydrophobicContact CG-CD2 3.7Å; F32-L176 HydrophobicContact CG-CG 4.21Å; F32-L176 HydrophobicContact CZ-CD2 4Å; I172-L176 WeakPolarHBondContact O-CB 3.28Å; I172-L176 PolarHBondContact O-N 3.33Å; G173-L176 PolarHBondContact O-N 3.2Å; V174-L176 VanDerWaalsContact C-N 3.26Å; V174-L176 PolarHBondContact O-N 3.32Å; L176-E178 VanDerWaalsContact C-N 3.29Å; L176-E178 PolarHBondContact O-N 2.89Å; L176-N179 PolarHBondContact O-N 3.09Å; L176-I180 HydrophobicContact CD1-CD1 3.31Å; L176-I180 HydrophobicContact CD1-CG1 4.13Å; L176-I180 HydrophobicContact CD2-CD1 4.43Å; L176-I180 HydrophobicContact CG-CD1 3.72Å; L176-I180 HydrophobicContact CG-CG1 4.41Å; L176-I180 VanDerWaalsContact O-CB 3.31Å; L176-I180 WeakPolarHBondContact O-CB 3.4Å; L176-I180 VanDerWaalsContact O-CG1 3.29Å; L176-I180 WeakPolarHBondContact O-CG1 3.43Å; L176-I180 PolarHBondContact O-N 3.35Å; L176-I180 VanDerWaalsContact O-N 3.1Å; L176-F189 HydrophobicContact CD2-CD1 4.48Å; L176-F189 HydrophobicContact CD2-CE1 4.01Å; L176-F189 HydrophobicContact CD2-CZ 4.14Å
177	V	74.8	Confident	71.2	Confident	40 Å²	40	44.4 Å²	44.4	24%	0.242	23%	0.232	C	C	.	.	H	α-helix	trans	-59.4	-41.8	-179.3	166.5	0	0	0	0	111.1	G173 V174 N179 I180 R185 F189	G173-V177 VanDerWaalsContact O-CG2 3.3Å; G173-V177 WeakPolarHBondContact O-CG2 3.02Å; G173-V177 PolarHBondContact O-N 3.17Å; G173-V177 VanDerWaalsContact O-N 3.08Å; V174-V177 PolarHBondContact O-N 3.39Å; V174-V177 VanDerWaalsContact O-N 3.12Å; V177-N179 VanDerWaalsContact C-N 3.34Å; V177-I180 PolarHBondContact O-N 3.48Å; V177-R185 VanDerWaalsContact CG1-CZ 3.42Å; V177-R185 PolarHBondContact O-NE 2.82Å; V177-R185 PolarHBondContact O-NH2 3.24Å; V177-F189 HydrophobicContact CG2-CE2 3.64Å; V177-F189 HydrophobicContact CG2-CZ 3.69Å
178	E	73.4	Confident	71.5	Confident	30 Å²	30	46.3 Å²	46.3	14%	0.14	24%	0.242	C	C	.	.	H	α-helix	trans	-71.4	-26.4	-179.7	-70.5	-179.7	173.3	0	0	113.5	L19 V174 L176 S235	L19-E178 WeakPolarHBondContact CD1-O 3.27Å; V174-E178 HydrophobicContact CG1-CG 4.17Å; V174-E178 WeakPolarHBondContact CG1-OE1 3.26Å; V174-E178 WeakPolarHBondContact O-CG 3.15Å; V174-E178 PolarHBondContact O-N 2.91Å; L176-E178 VanDerWaalsContact C-N 3.29Å; L176-E178 PolarHBondContact O-N 2.89Å; E178-S235 WeakPolarHBondContact OE2-CB 3.37Å; E178-S235 PolarHBondContact OE2-OG 3.13Å
179	N	73.5	Confident	71.5	Confident	0 Å²	0	46.8 Å²	46.8	0%	0	24%	0.242	C	C	.	.	H	α-helix	trans	-93.6	-7.9	178.9	-77.6	-84	0	0	0	113.6	Q25 Y175 L176 V177	Q25-N179 VanDerWaalsContact CG-O 3.24Å; Q25-N179 WeakPolarHBondContact CG-O 3.37Å; Y175-N179 WeakPolarHBondContact CE2-ND2 3.27Å; Y175-N179 WeakPolarHBondContact O-CB 3.36Å; Y175-N179 PolarHBondContact O-N 3.23Å; Y175-N179 PolarHBondContact O-ND2 3.39Å; L176-N179 PolarHBondContact O-N 3.09Å; V177-N179 VanDerWaalsContact C-N 3.34Å
180	I	72.2	Confident	71.8	Confident	9 Å²	9	45.5 Å²	45.5	5%	0.046	23%	0.229	C	C	.	.	S	Bend	trans	-120.6	142.5	-173.5	-64.5	-169.7	0	0	0	112.3	Y29 L176 V177 Q182 R185 L188	Y29-I180 HydrophobicContact CD2-CD1 4.25Å; L176-I180 HydrophobicContact CD1-CD1 3.31Å; L176-I180 HydrophobicContact CD1-CG1 4.13Å; L176-I180 HydrophobicContact CD2-CD1 4.43Å; L176-I180 HydrophobicContact CG-CD1 3.72Å; L176-I180 HydrophobicContact CG-CG1 4.41Å; L176-I180 VanDerWaalsContact O-CB 3.31Å; L176-I180 WeakPolarHBondContact O-CB 3.4Å; L176-I180 VanDerWaalsContact O-CG1 3.29Å; L176-I180 WeakPolarHBondContact O-CG1 3.43Å; L176-I180 PolarHBondContact O-N 3.35Å; L176-I180 VanDerWaalsContact O-N 3.1Å; V177-I180 PolarHBondContact O-N 3.48Å; I180-Q182 PolarHBondContact O-N 3.23Å; I180-R185 PolarHBondContact O-NE 3.37Å; I180-R185 PolarHBondContact O-NH2 3.27Å; I180-L188 HydrophobicContact CD1-CD1 3.91Å; I180-L188 HydrophobicContact CG2-CD1 3.53Å
181	I	69.5	Low	72.5	Confident	52 Å²	52	46 Å²	46	27%	0.267	23%	0.228	S	C	.	.			trans	-58.2	131.2	176.5	-59.3	168.3	0	0	0	111.3	L19 K183 H184	L19-I181 WeakPolarHBondContact O-CG1 3.47Å; I181-K183 VanDerWaalsContact C-N 3.26Å; I181-K183 HydrophobicContact CG2-CB 4.38Å; I181-K183 PolarHBondContact O-N 3.3Å; I181-K183 VanDerWaalsContact O-N 3.09Å; I181-H184 PolarHBondContact O-N 2.95Å; I181-H184 VanDerWaalsContact O-N 3.13Å
182	Q	65.7	Low	72.7	Confident	132 Å²	132	43.2 Å²	43.2	62%	0.617	21%	0.214	S	C	*	.	G	3₁₀ helix	trans	-49.4	-39.2	-177.1	-170	176.6	2.8	0	0	114.8	I180 H184 R185	I180-Q182 PolarHBondContact O-N 3.23Å; Q182-H184 PolarHBondContact O-N 3.34Å; Q182-R185 PolarHBondContact O-N 3.48Å
183	K	66.3	Low	73.1	Confident	178 Å²	178	43.1 Å²	43.1	77%	0.774	22%	0.215	S	C	*	.	G	3₁₀ helix	trans	-64.2	-21.3	-176.4	-63.4	-175	-179.9	-178.3	0	114.7	I181	I181-K183 VanDerWaalsContact C-N 3.26Å; I181-K183 HydrophobicContact CG2-CB 4.38Å; I181-K183 PolarHBondContact O-N 3.3Å; I181-K183 VanDerWaalsContact O-N 3.09Å
184	H	68.6	Low	73.6	Confident	76 Å²	76	45.3 Å²	45.3	35%	0.352	22%	0.22	S	C	.	.	G	3₁₀ helix	trans	-107.3	-2.8	-175.6	-63.1	-79.2	0	0	0	113.8	I181 Q182 L186 L187 L188	I181-H184 PolarHBondContact O-N 2.95Å; I181-H184 VanDerWaalsContact O-N 3.13Å; Q182-H184 PolarHBondContact O-N 3.34Å; H184-L186 PolarHBondContact O-N 2.81Å; H184-L187 PolarHBondContact O-N 2.87Å; H184-L188 HydrophobicContact CB-CD1 3.73Å; H184-L188 HydrophobicContact CB-CG 4.29Å; H184-L188 WeakPolarHBondContact O-CB 3.49Å; H184-L188 WeakPolarHBondContact O-CD1 3.2Å; H184-L188 VanDerWaalsContact O-CG 3.27Å; H184-L188 WeakPolarHBondContact O-CG 3.49Å; H184-L188 PolarHBondContact O-N 3.23Å
185	R	72.3	Confident	74.4	Confident	42 Å²	42	42.5 Å²	42.5	16%	0.158	20%	0.202	C	C	.	.	H	α-helix	trans	-57.1	-54	-170	-69.6	178.2	178.5	162.3	3.3	113.5	E16 V177 I180 Q182 L187 L188 F189	E16-R185 VanDerWaalsContact CD-NH2 3.28Å; E16-R185 IonicContact OE1-NH2 2.74Å; E16-R185 IonicContact OE2-CZ 3.65Å; E16-R185 IonicContact OE2-NH1 3.02Å; E16-R185 IonicContact OE2-NH2 3.51Å; E16-R185 PolarHBondContact OE2-NH2 2.71Å; V177-R185 VanDerWaalsContact CG1-CZ 3.42Å; V177-R185 PolarHBondContact O-NE 2.82Å; V177-R185 PolarHBondContact O-NH2 3.24Å; I180-R185 PolarHBondContact O-NE 3.37Å; I180-R185 PolarHBondContact O-NH2 3.27Å; Q182-R185 PolarHBondContact O-N 3.48Å; R185-L187 PolarHBondContact O-N 3.34Å; R185-L188 PolarHBondContact O-N 3.5Å; R185-F189 WeakPolarHBondContact O-CD2 3.23Å; R185-F189 PolarHBondContact O-N 2.95Å
186	L	67.1	Low	75	Confident	30 Å²	30	44 Å²	44	16%	0.157	21%	0.211	C	C	.	.	H	α-helix	trans	-62.6	-44.2	-176.9	179.9	57.9	0	0	0	112.4	H184 L188 F189 S190 D351 N407 L411	H184-L186 PolarHBondContact O-N 2.81Å; L186-L188 VanDerWaalsContact C-N 3.31Å; L186-L188 PolarHBondContact O-N 3.35Å; L186-F189 PolarHBondContact O-N 2.82Å; L186-S190 WeakPolarHBondContact O-CB 3.27Å; L186-S190 PolarHBondContact O-N 3.27Å; L186-S190 PolarHBondContact O-OG 3.44Å; L186-D351 HydrophobicContact CD2-CB 4.29Å; L186-D351 VanDerWaalsContact CD2-OD2 3.3Å; L186-D351 WeakPolarHBondContact CD2-OD2 3.36Å; L186-N407 HydrophobicContact CD1-CB 4.12Å; L186-L411 HydrophobicContact CB-CD1 4.15Å; L186-L411 HydrophobicContact CD1-CD1 3.61Å; L186-L411 HydrophobicContact CD1-CG 4.32Å; L186-L411 HydrophobicContact CD2-CD1 3.76Å; L186-L411 HydrophobicContact CG-CD1 4.01Å
187	L	70.7	Confident	75.7	Confident	39 Å²	39	43.9 Å²	43.9	20%	0.204	21%	0.21	C	C	.	.	H	α-helix	trans	-62.1	-43	178.4	-177.4	67.3	0	0	0	110.6	H184 R185 S190 I191 L349	H184-L187 PolarHBondContact O-N 2.87Å; R185-L187 PolarHBondContact O-N 3.34Å; L187-S190 PolarHBondContact O-N 3.31Å; L187-S190 VanDerWaalsContact O-N 3.14Å; L187-I191 HydrophobicContact CD1-CD1 3.93Å; L187-I191 HydrophobicContact CD1-CG1 4.2Å; L187-I191 HydrophobicContact CD2-CD1 4.21Å; L187-I191 HydrophobicContact CG-CD1 3.68Å; L187-I191 HydrophobicContact CG-CG1 4.29Å; L187-I191 VanDerWaalsContact O-CG1 3.31Å; L187-I191 WeakPolarHBondContact O-CG1 3.41Å; L187-I191 PolarHBondContact O-N 3.25Å; L187-L349 HydrophobicContact CD1-CD2 3.82Å
188	L	74.1	Confident	76.6	Confident	40 Å²	40	42.1 Å²	42.1	21%	0.209	20%	0.199	C	C	.	.	H	α-helix	trans	-66.3	-41.2	178.1	-73.5	167.6	0	0	0	112.2	Y29 I180 H184 R185 L186 S190 A192	Y29-L188 HydrophobicContact CD2-CD2 4.23Å; Y29-L188 HydrophobicContact CE2-CB 3.95Å; Y29-L188 HydrophobicContact CE2-CD2 3.62Å; Y29-L188 HydrophobicContact CE2-CG 4.32Å; I180-L188 HydrophobicContact CD1-CD1 3.91Å; I180-L188 HydrophobicContact CG2-CD1 3.53Å; H184-L188 HydrophobicContact CB-CD1 3.73Å; H184-L188 HydrophobicContact CB-CG 4.29Å; H184-L188 WeakPolarHBondContact O-CB 3.49Å; H184-L188 WeakPolarHBondContact O-CD1 3.2Å; H184-L188 VanDerWaalsContact O-CG 3.27Å; H184-L188 WeakPolarHBondContact O-CG 3.49Å; H184-L188 PolarHBondContact O-N 3.23Å; R185-L188 PolarHBondContact O-N 3.5Å; L186-L188 VanDerWaalsContact C-N 3.31Å; L186-L188 PolarHBondContact O-N 3.35Å; L188-S190 PolarHBondContact O-N 2.91Å; L188-A192 WeakPolarHBondContact O-CB 3.31Å; L188-A192 PolarHBondContact O-N 2.74Å
189	F	72.4	Confident	77.5	Confident	57 Å²	57	43.3 Å²	43.3	25%	0.25	21%	0.206	C	C	.	.	H	α-helix	trans	-64.2	-20.1	172.3	-82.9	-63	0	0	0	114.1	F32 L176 V177 R185 L186 A192	F32-F189 AromaticContact CE2-CE1 3.87Å; F32-F189 HydrophobicContact CE2-CE1 3.87Å; F32-F189 AromaticContact CZ-CD1 3.88Å; F32-F189 HydrophobicContact CZ-CD1 3.88Å; F32-F189 AromaticContact CZ-CE1 3.67Å; F32-F189 HydrophobicContact CZ-CE1 3.67Å; L176-F189 HydrophobicContact CD2-CD1 4.48Å; L176-F189 HydrophobicContact CD2-CE1 4.01Å; L176-F189 HydrophobicContact CD2-CZ 4.14Å; V177-F189 HydrophobicContact CG2-CE2 3.64Å; V177-F189 HydrophobicContact CG2-CZ 3.69Å; R185-F189 WeakPolarHBondContact O-CD2 3.23Å; R185-F189 PolarHBondContact O-N 2.95Å; L186-F189 PolarHBondContact O-N 2.82Å; F189-A192 CarbonylContact C-O 3.51Å
190	S	73.5	Confident	78.5	Confident	0 Å²	0	45.2 Å²	45.2	0%	0	21%	0.214	C	C	.	.	H	α-helix	trans	-95.2	-37.8	-178.5	-53.5	0	0	0	0	112.2	L186 L187 L188 V345 S348 N407	L186-S190 WeakPolarHBondContact O-CB 3.27Å; L186-S190 PolarHBondContact O-N 3.27Å; L186-S190 PolarHBondContact O-OG 3.44Å; L187-S190 PolarHBondContact O-N 3.31Å; L187-S190 VanDerWaalsContact O-N 3.14Å; L188-S190 PolarHBondContact O-N 2.91Å; S190-V345 WeakPolarHBondContact O-CG2 3.39Å; S190-S348 WeakPolarHBondContact OG-CB 3.4Å; S190-S348 PolarHBondContact OG-OG 3.46Å; S190-N407 PolarHBondContact OG-ND2 3.34Å
191	I	81	Confident	79.5	Confident	67 Å²	67	44.9 Å²	44.9	34%	0.344	21%	0.212	S	C	.	.	H	α-helix	trans	-68.4	-50.2	173	-66.6	171.8	0	0	0	108.9	L187 I196 W341	L187-I191 HydrophobicContact CD1-CD1 3.93Å; L187-I191 HydrophobicContact CD1-CG1 4.2Å; L187-I191 HydrophobicContact CD2-CD1 4.21Å; L187-I191 HydrophobicContact CG-CD1 3.68Å; L187-I191 HydrophobicContact CG-CG1 4.29Å; L187-I191 VanDerWaalsContact O-CG1 3.31Å; L187-I191 WeakPolarHBondContact O-CG1 3.41Å; L187-I191 PolarHBondContact O-N 3.25Å; I191-I196 WeakPolarHBondContact O-CD1 3.2Å; I191-I196 WeakPolarHBondContact O-CG1 3.47Å; I191-W341 PolarHBondContact O-NE1 3.24Å
192	A	75.5	Confident	80.7	Confident	3 Å²	3	42.7 Å²	42.7	3%	0.025	20%	0.202	C	C	.	.	S	Bend	trans	-93.2	-175.1	174.3	0	0	0	0	0	112.3	Y29 F32 L188 F189	Y29-A192 HydrophobicContact CE1-CB 4.03Å; Y29-A192 HydrophobicContact CE2-CB 3.62Å; Y29-A192 WeakPolarHBondContact OH-CB 3.44Å; Y29-A192 PolarHBondContact OH-N 3.33Å; F32-A192 HydrophobicContact CE1-CB 4.39Å; L188-A192 WeakPolarHBondContact O-CB 3.31Å; L188-A192 PolarHBondContact O-N 2.74Å; F189-A192 CarbonylContact C-O 3.51Å
193	G	83.2	Confident	82.1	Confident	5 Å²	5	41 Å²	41	5%	0.052	20%	0.196	C	C	.	.	S	Bend	trans	104.9	-153.6	170	0	0	0	0	0	113.4	Q33 N195 G197	Q33-G193 PolarHBondContact NE2-O 2.91Å; G193-N195 PolarHBondContact O-N 3.46Å; G193-G197 PolarHBondContact O-N 3.45Å; G193-G197 VanDerWaalsContact O-N 3.15Å
194	F	85.1	Confident	83.5	Confident	63 Å²	63	33.1 Å²	33.1	28%	0.276	16%	0.163	S	C	.	.	H	α-helix	trans	-64	-36	-169.4	-172.3	-97.7	0	0	0	113.3	A40 M43 G197 L198	A40-F194 HydrophobicContact CB-CD2 3.83Å; A40-F194 HydrophobicContact CB-CE2 3.74Å; A40-F194 HydrophobicContact CB-CZ 4.33Å; M43-F194 HydrophobicContact CB-CE2 4.43Å; M43-F194 HydrophobicContact CB-CZ 4.36Å; M43-F194 HydrophobicContact CG-CZ 4.32Å; M43-F194 HydrophobicContact SD-CE1 4.47Å; M43-F194 HydrophobicContact SD-CE2 3.84Å; M43-F194 HydrophobicContact SD-CZ 3.42Å; M43-F194 WeakPolarHBondContact SD-CZ 3.3Å; F194-G197 CarbonylContact O-C 3.37Å; F194-G197 WeakPolarHBondContact O-CA 3.46Å; F194-G197 PolarHBondContact O-N 3.21Å; F194-G197 VanDerWaalsContact O-N 3.08Å; F194-L198 HydrophobicContact CD1-CD1 4.1Å; F194-L198 HydrophobicContact CD1-CG 4.14Å; F194-L198 HydrophobicContact CE1-CD1 3.66Å; F194-L198 HydrophobicContact CE1-CD2 3.92Å; F194-L198 HydrophobicContact CE1-CG 3.72Å; F194-L198 HydrophobicContact CZ-CD1 4.49Å; F194-L198 HydrophobicContact CZ-CD2 3.92Å; F194-L198 HydrophobicContact CZ-CG 4.18Å; F194-L198 PolarHBondContact O-N 3.38Å
195	N	87.8	Confident	84.7	Confident	11 Å²	11	29.5 Å²	29.5	6%	0.059	15%	0.146	C	C	.	.	H	α-helix	trans	-65.3	-46	-177.4	-63.8	-53.7	0	0	0	112.6	G193 G197 L198 L199 R340 W341 S403	G193-N195 PolarHBondContact O-N 3.46Å; N195-G197 PolarHBondContact O-N 3.04Å; N195-L198 PolarHBondContact O-N 2.92Å; N195-L199 PolarHBondContact O-N 3.44Å; N195-R340 PolarHBondContact OD1-NE 3.3Å; N195-W341 HydrophobicContact CB-CB 4Å; N195-S403 PolarHBondContact OD1-OG 3.4Å; N195-S403 VanDerWaalsContact OD1-OG 3.14Å
196	I	90.8	Very high	85.8	Confident	47 Å²	47	32.6 Å²	32.6	24%	0.241	16%	0.161	C	C	.	.	H	α-helix	trans	-66.9	-32.3	171.8	-58.6	-165.5	0	0	0	110.2	F37 I191 L198 L199 Y200 W341	F37-I196 HydrophobicContact CE1-CB 4.31Å; F37-I196 HydrophobicContact CE1-CG2 3.73Å; F37-I196 HydrophobicContact CZ-CG2 4.05Å; I191-I196 WeakPolarHBondContact O-CD1 3.2Å; I191-I196 WeakPolarHBondContact O-CG1 3.47Å; I196-L198 VanDerWaalsContact C-N 3.3Å; I196-L198 PolarHBondContact O-N 3.22Å; I196-L199 WeakPolarHBondContact O-CB 3.27Å; I196-L199 PolarHBondContact O-N 3.34Å; I196-L199 VanDerWaalsContact O-N 3.14Å; I196-Y200 PolarHBondContact O-N 3.07Å; I196-W341 HydrophobicContact CD1-CZ2 4.47Å; I196-W341 VanDerWaalsContact CG1-CD1 3.47Å; I196-W341 HydrophobicContact CG1-CG 4.22Å
197	G	92.2	Very high	87.1	Confident	0 Å²	0	37 Å²	37	0%	0	19%	0.185	C	C	.	.	H	α-helix	trans	-60.6	-35.8	173.7	0	0	0	0	0	114.3	F37 G193 F194 N195 Y200 A201	F37-G197 VanDerWaalsContact CD1-CA 3.44Å; G193-G197 PolarHBondContact O-N 3.45Å; G193-G197 VanDerWaalsContact O-N 3.15Å; F194-G197 CarbonylContact O-C 3.37Å; F194-G197 WeakPolarHBondContact O-CA 3.46Å; F194-G197 PolarHBondContact O-N 3.21Å; F194-G197 VanDerWaalsContact O-N 3.08Å; N195-G197 PolarHBondContact O-N 3.04Å; G197-Y200 WeakPolarHBondContact O-CB 3.25Å; G197-Y200 PolarHBondContact O-N 3.21Å; G197-A201 PolarHBondContact O-N 3.01Å
198	L	92.8	Very high	88.2	Confident	3 Å²	3	36.1 Å²	36.1	2%	0.016	18%	0.181	C	C	.	.	H	α-helix	trans	-65	-44.7	171.5	-71.2	176.6	0	0	0	111	A40 A44 F194 N195 I196 Y200 A201 V202 L319 Y336 S337	A40-L198 HydrophobicContact CB-CD2 4.35Å; A40-L198 HydrophobicContact CB-CG 4.5Å; A44-L198 HydrophobicContact CB-CD2 4.19Å; F194-L198 HydrophobicContact CD1-CD1 4.1Å; F194-L198 HydrophobicContact CD1-CG 4.14Å; F194-L198 HydrophobicContact CE1-CD1 3.66Å; F194-L198 HydrophobicContact CE1-CD2 3.92Å; F194-L198 HydrophobicContact CE1-CG 3.72Å; F194-L198 HydrophobicContact CZ-CD1 4.49Å; F194-L198 HydrophobicContact CZ-CD2 3.92Å; F194-L198 HydrophobicContact CZ-CG 4.18Å; F194-L198 PolarHBondContact O-N 3.38Å; N195-L198 PolarHBondContact O-N 2.92Å; I196-L198 VanDerWaalsContact C-N 3.3Å; I196-L198 PolarHBondContact O-N 3.22Å; L198-Y200 VanDerWaalsContact C-N 3.29Å; L198-Y200 PolarHBondContact O-N 2.95Å; L198-A201 WeakPolarHBondContact O-CA 3.37Å; L198-A201 VanDerWaalsContact O-CB 3.31Å; L198-A201 WeakPolarHBondContact O-CB 3.48Å; L198-A201 PolarHBondContact O-N 3.24Å; L198-V202 WeakPolarHBondContact O-CG2 3.26Å; L198-V202 PolarHBondContact O-N 3.06Å; L198-L319 HydrophobicContact CD2-CD1 4.19Å; L198-L319 HydrophobicContact CD2-CD2 4.35Å; L198-Y336 HydrophobicContact CD1-CE1 4.03Å; L198-S337 WeakPolarHBondContact CB-OG 3.38Å
199	L	93.6	Very high	89.1	Confident	55 Å²	55	39.2 Å²	39.2	29%	0.288	19%	0.194	S	C	.	.	H	α-helix	trans	-59.3	-41.4	176.1	-175.3	64.4	0	0	0	111.9	N195 I196 A201 V202 L203 T334 L338	N195-L199 PolarHBondContact O-N 3.44Å; I196-L199 WeakPolarHBondContact O-CB 3.27Å; I196-L199 PolarHBondContact O-N 3.34Å; I196-L199 VanDerWaalsContact O-N 3.14Å; L199-A201 VanDerWaalsContact C-N 3.35Å; L199-V202 PolarHBondContact O-N 3.45Å; L199-L203 PolarHBondContact O-N 3.26Å; L199-T334 HydrophobicContact CD1-CG2 4.1Å; L199-L338 HydrophobicContact CD1-CD2 4.29Å; L199-L338 HydrophobicContact CD1-CG 4.25Å; L199-L338 HydrophobicContact CD2-CD2 3.82Å
200	Y	93.4	Very high	90.2	Very high	40 Å²	40	39 Å²	39	16%	0.157	19%	0.194	C	C	.	.	H	α-helix	trans	-59.3	-44.4	171.6	168.3	-97	0	0	0	111.7	F37 A41 I196 G197 L198 V202 L203 V204 I221	F37-Y200 HydrophobicContact CB-CD1 3.66Å; F37-Y200 HydrophobicContact CB-CE1 3.92Å; F37-Y200 HydrophobicContact CB-CG 4.17Å; F37-Y200 HydrophobicContact CD1-CD1 4.38Å; F37-Y200 HydrophobicContact CD1-CG 4.16Å; F37-Y200 HydrophobicContact CD2-CD1 4.34Å; F37-Y200 HydrophobicContact CD2-CD2 4.09Å; F37-Y200 HydrophobicContact CD2-CE2 4.43Å; F37-Y200 HydrophobicContact CD2-CG 4.04Å; F37-Y200 HydrophobicContact CE1-CG 4.4Å; F37-Y200 HydrophobicContact CE2-CD2 4.27Å; F37-Y200 HydrophobicContact CE2-CG 4.41Å; F37-Y200 AromaticContact CG-CD1 3.93Å; F37-Y200 HydrophobicContact CG-CD1 3.93Å; F37-Y200 HydrophobicContact CG-CD2 4.42Å; F37-Y200 HydrophobicContact CG-CE1 4.46Å; F37-Y200 AromaticContact CG-CG 3.9Å; F37-Y200 HydrophobicContact CG-CG 3.9Å; A41-Y200 HydrophobicContact CB-CD1 4.48Å; A41-Y200 HydrophobicContact CB-CE1 4.37Å; I196-Y200 PolarHBondContact O-N 3.07Å; G197-Y200 WeakPolarHBondContact O-CB 3.25Å; G197-Y200 PolarHBondContact O-N 3.21Å; L198-Y200 VanDerWaalsContact C-N 3.29Å; L198-Y200 PolarHBondContact O-N 2.95Å; Y200-V202 VanDerWaalsContact C-N 3.3Å; Y200-V202 PolarHBondContact O-N 2.9Å; Y200-L203 WeakPolarHBondContact O-CB 3.29Å; Y200-L203 PolarHBondContact O-N 2.88Å; Y200-L203 VanDerWaalsContact O-N 3.16Å; Y200-V204 HydrophobicContact CD1-CG2 4.29Å; Y200-V204 HydrophobicContact CD2-CG2 4.12Å; Y200-V204 HydrophobicContact CE1-CG2 3.77Å; Y200-V204 HydrophobicContact CE2-CG2 3.57Å; Y200-V204 HydrophobicContact CG-CG2 4.45Å; Y200-V204 WeakPolarHBondContact O-CG2 3.26Å; Y200-V204 PolarHBondContact O-N 3.05Å; Y200-I221 HydrophobicContact CE1-CG2 4.09Å; Y200-I221 WeakPolarHBondContact OH-CB 3.3Å
201	A	94.2	Very high	91.2	Very high	2 Å²	2	39 Å²	39	2%	0.017	19%	0.194	C	C	.	.	H	α-helix	trans	-60.3	-40.3	177.4	0	0	0	0	0	112.1	A41 A44 G197 L198 L199 V204 A205	A41-A201 HydrophobicContact CB-CB 4Å; A44-A201 HydrophobicContact CB-CB 3.91Å; G197-A201 PolarHBondContact O-N 3.01Å; L198-A201 WeakPolarHBondContact O-CA 3.37Å; L198-A201 VanDerWaalsContact O-CB 3.31Å; L198-A201 WeakPolarHBondContact O-CB 3.48Å; L198-A201 PolarHBondContact O-N 3.24Å; L199-A201 VanDerWaalsContact C-N 3.35Å; A201-V204 PolarHBondContact O-N 2.96Å; A201-A205 VanDerWaalsContact O-CB 3.31Å; A201-A205 WeakPolarHBondContact O-CB 3.34Å; A201-A205 PolarHBondContact O-N 3.46Å
202	V	94.9	Very high	91.8	Very high	7 Å²	7	39.7 Å²	39.7	4%	0.042	19%	0.192	C	C	.	.	H	α-helix	trans	-62.2	-46	173.9	-171.7	0	0	0	0	111.1	Y48 L198 L199 Y200 V204 A205 F206 S333 T334	Y48-V202 WeakPolarHBondContact OH-CG2 3.43Å; L198-V202 WeakPolarHBondContact O-CG2 3.26Å; L198-V202 PolarHBondContact O-N 3.06Å; L199-V202 PolarHBondContact O-N 3.45Å; Y200-V202 VanDerWaalsContact C-N 3.3Å; Y200-V202 PolarHBondContact O-N 2.9Å; V202-V204 PolarHBondContact O-N 2.93Å; V202-A205 PolarHBondContact O-N 2.91Å; V202-F206 WeakPolarHBondContact O-CB 3.35Å; V202-F206 PolarHBondContact O-N 3.4Å; V202-S333 VanDerWaalsContact CG2-CB 3.47Å; V202-T334 WeakPolarHBondContact CG1-OG1 3.35Å
203	L	95.5	Very high	92.7	Very high	96 Å²	96	43.8 Å²	43.8	50%	0.503	21%	0.213	S	C	.	.	H	α-helix	trans	-59.6	-46.7	178.9	178.3	63.2	0	0	0	111.5	L199 Y200 F206 L207	L199-L203 PolarHBondContact O-N 3.26Å; Y200-L203 WeakPolarHBondContact O-CB 3.29Å; Y200-L203 PolarHBondContact O-N 2.88Å; Y200-L203 VanDerWaalsContact O-N 3.16Å; L203-F206 PolarHBondContact O-N 3.26Å; L203-L207 HydrophobicContact CD1-CD1 4.02Å; L203-L207 HydrophobicContact CD1-CG 4.24Å; L203-L207 HydrophobicContact CG-CD1 4.05Å; L203-L207 WeakPolarHBondContact O-CB 3.46Å; L203-L207 VanDerWaalsContact O-CG 3.27Å; L203-L207 WeakPolarHBondContact O-CG 3.33Å; L203-L207 PolarHBondContact O-N 2.93Å
204	V	94.7	Very high	93.2	Very high	13 Å²	13	43.7 Å²	43.7	8%	0.079	21%	0.211	C	C	.	.	H	α-helix	trans	-65.7	-42	178.1	179.2	0	0	0	0	111.1	Y200 A201 V202 F206 L207 T208 L214 C217	Y200-V204 HydrophobicContact CD1-CG2 4.29Å; Y200-V204 HydrophobicContact CD2-CG2 4.12Å; Y200-V204 HydrophobicContact CE1-CG2 3.77Å; Y200-V204 HydrophobicContact CE2-CG2 3.57Å; Y200-V204 HydrophobicContact CG-CG2 4.45Å; Y200-V204 WeakPolarHBondContact O-CG2 3.26Å; Y200-V204 PolarHBondContact O-N 3.05Å; A201-V204 PolarHBondContact O-N 2.96Å; V202-V204 PolarHBondContact O-N 2.93Å; V204-F206 VanDerWaalsContact C-N 3.32Å; V204-F206 PolarHBondContact O-N 3.12Å; V204-L207 PolarHBondContact O-N 3.41Å; V204-T208 HydrophobicContact CG1-CG2 3.96Å; V204-T208 WeakPolarHBondContact O-CB 3.27Å; V204-T208 VanDerWaalsContact O-CG2 3.32Å; V204-T208 WeakPolarHBondContact O-CG2 3.38Å; V204-T208 PolarHBondContact O-N 3.08Å; V204-T208 PolarHBondContact O-OG1 2.54Å; V204-L214 HydrophobicContact CB-CD1 4.25Å; V204-L214 HydrophobicContact CG1-CD1 3.78Å; V204-C217 HydrophobicContact CG1-CB 3.64Å
205	A	94.6	Very high	93.5	Very high	0 Å²	0	41 Å²	41	0%	0	20%	0.2	C	C	.	.	H	α-helix	trans	-60	-43.4	176.1	0	0	0	0	0	111.7	Y48 F92 A201 V202 Q209 L214 Y330	Y48-A205 HydrophobicContact CD1-CB 3.97Å; Y48-A205 HydrophobicContact CD2-CB 3.81Å; Y48-A205 HydrophobicContact CE1-CB 3.89Å; Y48-A205 HydrophobicContact CE2-CB 3.73Å; Y48-A205 HydrophobicContact CG-CB 3.93Å; F92-A205 HydrophobicContact CE2-CB 4.47Å; A201-A205 VanDerWaalsContact O-CB 3.31Å; A201-A205 WeakPolarHBondContact O-CB 3.34Å; A201-A205 PolarHBondContact O-N 3.46Å; V202-A205 PolarHBondContact O-N 2.91Å; A205-Q209 PolarHBondContact O-N 2.72Å; A205-L214 HydrophobicContact CB-CD1 4.01Å; A205-L214 HydrophobicContact CB-CD2 4.27Å; A205-Y330 HydrophobicContact CB-CE1 4.15Å
206	F	94.4	Very high	93.7	Very high	106 Å²	106	41.9 Å²	41.9	47%	0.465	20%	0.204	S	C	.	.	H	α-helix	trans	-64.4	-40.2	177.4	179.8	-100.8	0	0	0	112.8	V202 L203 V204 Q209 Y330	V202-F206 WeakPolarHBondContact O-CB 3.35Å; V202-F206 PolarHBondContact O-N 3.4Å; L203-F206 PolarHBondContact O-N 3.26Å; V204-F206 VanDerWaalsContact C-N 3.32Å; V204-F206 PolarHBondContact O-N 3.12Å; F206-Q209 WeakPolarHBondContact O-CG 3.44Å; F206-Y330 HydrophobicContact CB-CD1 3.93Å; F206-Y330 HydrophobicContact CB-CE1 4.07Å; F206-Y330 HydrophobicContact CB-CG 4.49Å; F206-Y330 HydrophobicContact CD2-CD1 4.2Å; F206-Y330 AromaticContact CD2-CD2 4Å; F206-Y330 HydrophobicContact CD2-CD2 4Å; F206-Y330 HydrophobicContact CD2-CE1 4.46Å; F206-Y330 HydrophobicContact CD2-CE2 4.26Å; F206-Y330 AromaticContact CD2-CG 3.95Å; F206-Y330 HydrophobicContact CD2-CG 3.95Å
207	L	95	Very high	93.8	Very high	124 Å²	124	42 Å²	42	65%	0.649	21%	0.209	S	C	*	.	H	α-helix	trans	-75.8	-32.4	179.9	-68.7	174.2	0	0	0	113.3	L203 V204	L203-L207 HydrophobicContact CD1-CD1 4.02Å; L203-L207 HydrophobicContact CD1-CG 4.24Å; L203-L207 HydrophobicContact CG-CD1 4.05Å; L203-L207 WeakPolarHBondContact O-CB 3.46Å; L203-L207 VanDerWaalsContact O-CG 3.27Å; L203-L207 WeakPolarHBondContact O-CG 3.33Å; L203-L207 PolarHBondContact O-N 2.93Å; V204-L207 PolarHBondContact O-N 3.41Å
208	T	93.8	Very high	93.7	Very high	20 Å²	20	42.1 Å²	42.1	12%	0.123	21%	0.209	C	C	.	.	H	α-helix	trans	-89.7	-33.1	-174.9	54.4	0	0	0	0	113.4	V204 H210 L213 C217	V204-T208 HydrophobicContact CG1-CG2 3.96Å; V204-T208 WeakPolarHBondContact O-CB 3.27Å; V204-T208 VanDerWaalsContact O-CG2 3.32Å; V204-T208 WeakPolarHBondContact O-CG2 3.38Å; V204-T208 PolarHBondContact O-N 3.08Å; V204-T208 PolarHBondContact O-OG1 2.54Å; T208-H210 PolarHBondContact O-N 3.39Å; T208-L213 HydrophobicContact CG2-CB 3.93Å; T208-C217 HydrophobicContact CG2-CB 4.17Å
209	Q	93.2	Very high	93.5	Very high	104 Å²	104	42 Å²	42	49%	0.486	21%	0.209	S	C	.	.			trans	50.3	11.7	179.5	-57.6	-166.1	-39.2	0	0	116.5	Y93 A205 F206	Y93-Q209 PolarHBondContact N-O 2.83Å; A205-Q209 PolarHBondContact O-N 2.72Å; F206-Q209 WeakPolarHBondContact O-CG 3.44Å
210	H	94.4	Very high	93.3	Very high	53 Å²	53	41.9 Å²	41.9	25%	0.245	21%	0.212	C	C	.	.	B	Isolated β-bridge	trans	-146.4	133.2	-175.4	-164.9	-62.6	0	0	0	109.8	Y93 E98 T208 R212 L213 L214	Y93-H210 AromaticContact CD1-CD2 3.59Å; Y93-H210 AromaticContact CD1-CE1 3.59Å; Y93-H210 AromaticContact CD1-NE2 3.23Å; Y93-H210 WeakPolarHBondContact CD1-NE2 3.4Å; Y93-H210 AromaticContact CE1-CE1 3.97Å; Y93-H210 AromaticContact CE1-NE2 3.59Å; E98-H210 IonicContact OE2-CE1 2.66Å; T208-H210 PolarHBondContact O-N 3.39Å; H210-R212 VanDerWaalsContact C-N 3.34Å; H210-R212 PolarHBondContact ND1-N 3.36Å; H210-R212 PolarHBondContact O-N 2.97Å; H210-L213 HydrophobicContact CB-CB 4.45Å; H210-L213 HydrophobicContact CB-CD1 4.31Å; H210-L213 HydrophobicContact CB-CG 4.47Å; H210-L213 PolarHBondContact O-N 3Å; H210-L214 WeakPolarHBondContact O-CB 3.45Å; H210-L214 PolarHBondContact O-N 2.9Å
211	W	94.3	Very high	93	Very high	0 Å²	0	41.5 Å²	41.5	0%	0	21%	0.213	C	C	.	.	H	α-helix	trans	-58.6	-39.7	-174.3	72.1	-95	0	0	0	114.2	A49 F92 Y93 I95 E98 W99 L154 L214 V215	A49-W211 HydrophobicContact CB-CB 3.89Å; F92-W211 HydrophobicContact CE1-CB 4.03Å; F92-W211 HydrophobicContact CZ-CB 4.2Å; Y93-W211 PolarHBondContact O-N 3.49Å; Y93-W211 VanDerWaalsContact O-N 3.09Å; I95-W211 HydrophobicContact CG1-CB 4.14Å; I95-W211 HydrophobicContact CG1-CD2 3.64Å; I95-W211 HydrophobicContact CG1-CE3 4.06Å; I95-W211 HydrophobicContact CG1-CG 3.73Å; E98-W211 VanDerWaalsContact OE2-CE2 3.23Å; E98-W211 VanDerWaalsContact OE2-CZ2 3.28Å; E98-W211 WeakPolarHBondContact OE2-CZ2 3.38Å; E98-W211 PolarHBondContact OE2-NE1 3.45Å; W99-W211 AromaticContact CH2-CH2 3.86Å; W99-W211 HydrophobicContact CH2-CH2 3.86Å; W99-W211 HydrophobicContact CH2-CZ2 4.17Å; W99-W211 AromaticContact CZ2-CH2 3.81Å; W99-W211 HydrophobicContact CZ2-CH2 3.81Å; W99-W211 AromaticContact CZ2-CZ2 3.86Å; W99-W211 HydrophobicContact CZ2-CZ2 3.86Å; L154-W211 HydrophobicContact CD1-CZ3 4.42Å; L154-W211 HydrophobicContact CD2-CE3 4.25Å; L154-W211 HydrophobicContact CD2-CH2 4.05Å; L154-W211 HydrophobicContact CD2-CZ3 3.64Å; W211-L214 PolarHBondContact O-N 3.29Å; W211-V215 PolarHBondContact O-N 3.33Å
212	R	95	Very high	92.4	Very high	82 Å²	82	41.5 Å²	41.5	31%	0.309	21%	0.213	S	C	.	.	H	α-helix	trans	-60	-49.2	176	-66	-177.2	179.9	-174.3	-7.6	112.5	E98 G146 H210 L214 V215 I216	E98-R212 IonicContact OE1-CZ 3.49Å; E98-R212 VanDerWaalsContact OE1-CZ 3.29Å; E98-R212 IonicContact OE1-NE 3.87Å; E98-R212 PolarHBondContact OE1-NE 2.84Å; E98-R212 IonicContact OE1-NH2 3.7Å; E98-R212 PolarHBondContact OE1-NH2 3.15Å; E98-R212 IonicContact OE2-CZ 2.67Å; E98-R212 IonicContact OE2-NE 2.68Å; E98-R212 PolarHBondContact OE2-NE 2.88Å; E98-R212 IonicContact OE2-NH2 3.66Å; G146-R212 WeakPolarHBondContact O-CB 3.48Å; G146-R212 WeakPolarHBondContact O-CG 3.41Å; H210-R212 VanDerWaalsContact C-N 3.34Å; H210-R212 PolarHBondContact ND1-N 3.36Å; H210-R212 PolarHBondContact O-N 2.97Å; R212-L214 VanDerWaalsContact C-N 3.35Å; R212-V215 WeakPolarHBondContact O-CG1 3.39Å; R212-V215 PolarHBondContact O-N 2.94Å; R212-I216 WeakPolarHBondContact O-CD1 3.07Å; R212-I216 VanDerWaalsContact O-CG1 3.26Å; R212-I216 WeakPolarHBondContact O-CG1 3.33Å; R212-I216 PolarHBondContact O-N 3.2Å; R212-I216 VanDerWaalsContact O-N 3.16Å
213	L	94.2	Very high	91.8	Very high	88 Å²	88	45.6 Å²	45.6	46%	0.461	23%	0.234	S	C	.	.	H	α-helix	trans	-66.7	-39.5	177.7	-68.4	176.9	0	0	0	110.9	T208 H210 V215 I216 C217	T208-L213 HydrophobicContact CG2-CB 3.93Å; H210-L213 HydrophobicContact CB-CB 4.45Å; H210-L213 HydrophobicContact CB-CD1 4.31Å; H210-L213 HydrophobicContact CB-CG 4.47Å; H210-L213 PolarHBondContact O-N 3Å; L213-V215 PolarHBondContact O-N 3.37Å; L213-I216 PolarHBondContact O-N 2.77Å; L213-C217 WeakPolarHBondContact O-CB 3.29Å; L213-C217 PolarHBondContact O-N 3.36Å; L213-C217 PolarHBondContact O-SG 3.04Å; L213-C217 VanDerWaalsContact O-SG 3.33Å
214	L	93.7	Very high	91.3	Very high	3 Å²	3	45.1 Å²	45.1	2%	0.016	23%	0.232	C	C	.	.	H	α-helix	trans	-56.3	-49	176.5	178.7	58.2	0	0	0	111.6	Y45 Y48 F92 V204 A205 H210 W211 R212 S218	Y45-L214 HydrophobicContact CD2-CD2 3.9Å; Y45-L214 HydrophobicContact CD2-CG 4.03Å; Y45-L214 HydrophobicContact CE2-CD2 4.36Å; Y45-L214 HydrophobicContact CE2-CG 4.43Å; Y48-L214 HydrophobicContact CD2-CD2 4.22Å; Y48-L214 HydrophobicContact CG-CD2 4.37Å; F92-L214 HydrophobicContact CE2-CB 4.42Å; F92-L214 HydrophobicContact CE2-CD2 4Å; F92-L214 HydrophobicContact CZ-CB 4.15Å; F92-L214 HydrophobicContact CZ-CD2 3.62Å; V204-L214 HydrophobicContact CB-CD1 4.25Å; V204-L214 HydrophobicContact CG1-CD1 3.78Å; A205-L214 HydrophobicContact CB-CD1 4.01Å; A205-L214 HydrophobicContact CB-CD2 4.27Å; H210-L214 WeakPolarHBondContact O-CB 3.45Å; H210-L214 PolarHBondContact O-N 2.9Å; W211-L214 PolarHBondContact O-N 3.29Å; R212-L214 VanDerWaalsContact C-N 3.35Å; L214-S218 WeakPolarHBondContact O-CB 3.35Å; L214-S218 PolarHBondContact O-N 3.48Å; L214-S218 PolarHBondContact O-OG 3.4Å
215	V	91.9	Very high	90.9	Very high	6 Å²	6	44.6 Å²	44.6	4%	0.036	23%	0.228	C	C	.	.	H	α-helix	trans	-68.7	-36.9	-179.8	68.1	0	0	0	0	112.3	Y45 W211 R212 L213 N219	Y45-V215 HydrophobicContact CD2-CB 4.25Å; Y45-V215 HydrophobicContact CE2-CB 3.67Å; Y45-V215 HydrophobicContact CE2-CG2 4.39Å; W211-V215 PolarHBondContact O-N 3.33Å; R212-V215 WeakPolarHBondContact O-CG1 3.39Å; R212-V215 PolarHBondContact O-N 2.94Å; L213-V215 PolarHBondContact O-N 3.37Å; V215-N219 WeakPolarHBondContact CG2-ND2 3.42Å; V215-N219 WeakPolarHBondContact O-CB 3.33Å; V215-N219 PolarHBondContact O-N 3.41Å; V215-N219 VanDerWaalsContact O-N 3.16Å; V215-N219 PolarHBondContact O-ND2 3.22Å
216	I	92.1	Very high	90.2	Very high	31 Å²	31	46.5 Å²	46.5	16%	0.159	24%	0.238	C	C	.	.	H	α-helix	trans	-63.9	-55.1	176.8	-68.4	165.7	0	0	0	109.7	V143 F147 R212 L213 S218 N219 S220	V143-I216 HydrophobicContact CG1-CG2 4.49Å; F147-I216 HydrophobicContact CE1-CD1 4.32Å; F147-I216 HydrophobicContact CE2-CD1 4.01Å; F147-I216 HydrophobicContact CE2-CG1 4.37Å; F147-I216 HydrophobicContact CZ-CD1 3.91Å; R212-I216 WeakPolarHBondContact O-CD1 3.07Å; R212-I216 VanDerWaalsContact O-CG1 3.26Å; R212-I216 WeakPolarHBondContact O-CG1 3.33Å; R212-I216 PolarHBondContact O-N 3.2Å; R212-I216 VanDerWaalsContact O-N 3.16Å; L213-I216 PolarHBondContact O-N 2.77Å; I216-S218 PolarHBondContact O-N 3.37Å; I216-N219 PolarHBondContact O-N 3.21Å; I216-S220 WeakPolarHBondContact O-CB 3.37Å; I216-S220 PolarHBondContact O-N 3.41Å; I216-S220 PolarHBondContact O-OG 3.18Å
217	C	92.2	Very high	89.7	Confident	50 Å²	50	45.5 Å²	45.5	34%	0.338	24%	0.241	S	C	.	.	H	α-helix	trans	-61.7	-43	-178.6	-68.1	0	0	0	0	111.9	V204 T208 L213 N219 S220 I221	V204-C217 HydrophobicContact CG1-CB 3.64Å; T208-C217 HydrophobicContact CG2-CB 4.17Å; L213-C217 WeakPolarHBondContact O-CB 3.29Å; L213-C217 PolarHBondContact O-N 3.36Å; L213-C217 PolarHBondContact O-SG 3.04Å; L213-C217 VanDerWaalsContact O-SG 3.33Å; C217-N219 VanDerWaalsContact C-N 3.29Å; C217-N219 PolarHBondContact O-N 3.17Å; C217-S220 PolarHBondContact O-N 3.34Å; C217-I221 PolarHBondContact O-N 3.03Å
218	S	90.1	Very high	89.2	Confident	1 Å²	1	41.1 Å²	41.1	1%	0.007	22%	0.218	C	C	.	.	H	α-helix	trans	-63.4	-31	179.8	-62.6	0	0	0	0	113.6	L214 I216 I221	L214-S218 WeakPolarHBondContact O-CB 3.35Å; L214-S218 PolarHBondContact O-N 3.48Å; L214-S218 PolarHBondContact O-OG 3.4Å; I216-S218 PolarHBondContact O-N 3.37Å; S218-I221 VanDerWaalsContact O-CG2 3.28Å; S218-I221 WeakPolarHBondContact O-CG2 3.37Å
219	N	88.8	Confident	88.7	Confident	2 Å²	2	42.4 Å²	42.4	1%	0.011	22%	0.223	C	C	.	.	H	α-helix	trans	-92.3	-24.1	177.4	-71.9	-71.9	0	0	0	112.7	N42 V143 V215 I216 C217 I221 G222 L223	N42-N219 PolarHBondContact ND2-OD1 3.16Å; V143-N219 HydrophobicContact CG2-CB 3.84Å; V215-N219 WeakPolarHBondContact CG2-ND2 3.42Å; V215-N219 WeakPolarHBondContact O-CB 3.33Å; V215-N219 PolarHBondContact O-N 3.41Å; V215-N219 VanDerWaalsContact O-N 3.16Å; V215-N219 PolarHBondContact O-ND2 3.22Å; I216-N219 PolarHBondContact O-N 3.21Å; C217-N219 VanDerWaalsContact C-N 3.29Å; C217-N219 PolarHBondContact O-N 3.17Å; N219-I221 VanDerWaalsContact C-N 3.3Å; N219-I221 PolarHBondContact O-N 3.34Å; N219-G222 PolarHBondContact O-N 3.47Å; N219-G222 VanDerWaalsContact O-N 3.1Å; N219-L223 PolarHBondContact O-N 3.1Å
220	S	88.3	Confident	88.2	Confident	51 Å²	51	39.9 Å²	39.9	36%	0.357	23%	0.226	S	C	.	.	H	α-helix	trans	-64.2	-33.9	176.7	-61.7	0	0	0	0	112.3	I216 C217 G222 L223 L224	I216-S220 WeakPolarHBondContact O-CB 3.37Å; I216-S220 PolarHBondContact O-N 3.41Å; I216-S220 PolarHBondContact O-OG 3.18Å; C217-S220 PolarHBondContact O-N 3.34Å; S220-G222 PolarHBondContact O-N 2.96Å; S220-L223 VanDerWaalsContact O-CB 3.32Å; S220-L223 WeakPolarHBondContact O-CB 3.35Å; S220-L223 PolarHBondContact O-N 3.29Å; S220-L223 VanDerWaalsContact O-N 3.1Å; S220-L224 PolarHBondContact O-N 2.97Å
221	I	86.9	Confident	87.7	Confident	32 Å²	32	42.7 Å²	42.7	16%	0.164	24%	0.242	C	C	.	.	H	α-helix	trans	-64.4	-31	174.1	-161.1	62.5	0	0	0	112.4	L34 F37 T38 Y200 C217 S218 N219 L223 L224 A225	L34-I221 HydrophobicContact CD2-CD1 3.58Å; L34-I221 HydrophobicContact CD2-CG1 3.63Å; F37-I221 HydrophobicContact CB-CG2 4.41Å; F37-I221 HydrophobicContact CD2-CG1 4.5Å; T38-I221 WeakPolarHBondContact OG1-CG2 3.19Å; Y200-I221 HydrophobicContact CE1-CG2 4.09Å; Y200-I221 WeakPolarHBondContact OH-CB 3.3Å; C217-I221 PolarHBondContact O-N 3.03Å; S218-I221 VanDerWaalsContact O-CG2 3.28Å; S218-I221 WeakPolarHBondContact O-CG2 3.37Å; N219-I221 VanDerWaalsContact C-N 3.3Å; N219-I221 PolarHBondContact O-N 3.34Å; I221-L223 VanDerWaalsContact C-N 3.34Å; I221-L224 HydrophobicContact CD1-CD2 4.2Å; I221-L224 WeakPolarHBondContact O-CB 3.33Å; I221-L224 PolarHBondContact O-N 3.47Å; I221-A225 PolarHBondContact O-N 3.47Å
222	G	83.4	Confident	87.3	Confident	2 Å²	2	43.4 Å²	43.4	2%	0.021	25%	0.245	C	C	.	.	H	α-helix	trans	-71	-30.6	173.8	0	0	0	0	0	112.3	T38 L139 N219 S220 L224 A225 L226	T38-G222 WeakPolarHBondContact OG1-CA 3.45Å; T38-G222 PolarHBondContact OG1-N 3.21Å; L139-G222 WeakPolarHBondContact CD1-O 3.5Å; N219-G222 PolarHBondContact O-N 3.47Å; N219-G222 VanDerWaalsContact O-N 3.1Å; S220-G222 PolarHBondContact O-N 2.96Å; G222-L224 VanDerWaalsContact C-N 3.29Å; G222-L224 PolarHBondContact O-N 3.16Å; G222-A225 WeakPolarHBondContact O-CA 3.3Å; G222-A225 VanDerWaalsContact O-CB 3.26Å; G222-A225 WeakPolarHBondContact O-CB 3.18Å; G222-A225 PolarHBondContact O-N 3.43Å; G222-A225 VanDerWaalsContact O-N 3.09Å; G222-L226 PolarHBondContact O-N 3.31Å; G222-L226 VanDerWaalsContact O-N 3.11Å
223	L	82.1	Confident	86.8	Confident	94 Å²	94	43.2 Å²	43.2	49%	0.492	25%	0.247	S	C	.	.	H	α-helix	trans	-63.3	-37.1	171.6	-176.7	60.6	0	0	0	111.4	N219 S220 I221 A225 L226 V227	N219-L223 PolarHBondContact O-N 3.1Å; S220-L223 VanDerWaalsContact O-CB 3.32Å; S220-L223 WeakPolarHBondContact O-CB 3.35Å; S220-L223 PolarHBondContact O-N 3.29Å; S220-L223 VanDerWaalsContact O-N 3.1Å; I221-L223 VanDerWaalsContact C-N 3.34Å; L223-A225 VanDerWaalsContact C-N 3.29Å; L223-A225 PolarHBondContact O-N 3.12Å; L223-L226 HydrophobicContact CD1-CD1 4.02Å; L223-L226 WeakPolarHBondContact O-CB 3.39Å; L223-L226 PolarHBondContact O-N 3.35Å; L223-L226 VanDerWaalsContact O-N 3.12Å; L223-V227 PolarHBondContact O-N 2.95Å
224	L	84.9	Confident	86.4	Confident	86 Å²	86	43.6 Å²	43.6	45%	0.45	25%	0.246	S	C	.	.	H	α-helix	trans	-62	-38.9	171.4	-178.6	62.4	0	0	0	111.5	L34 S220 I221 G222 L226 V227 I228	L34-L224 HydrophobicContact CD1-CB 4.4Å; L34-L224 HydrophobicContact CD1-CD2 3.99Å; L34-L224 HydrophobicContact CD1-CG 3.93Å; L34-L224 HydrophobicContact CD2-CD2 4.41Å; S220-L224 PolarHBondContact O-N 2.97Å; I221-L224 HydrophobicContact CD1-CD2 4.2Å; I221-L224 WeakPolarHBondContact O-CB 3.33Å; I221-L224 PolarHBondContact O-N 3.47Å; G222-L224 VanDerWaalsContact C-N 3.29Å; G222-L224 PolarHBondContact O-N 3.16Å; L224-L226 VanDerWaalsContact C-N 3.26Å; L224-L226 PolarHBondContact O-N 3.2Å; L224-V227 WeakPolarHBondContact O-CB 3.48Å; L224-V227 PolarHBondContact O-N 2.71Å; L224-V227 VanDerWaalsContact O-N 3.11Å; L224-I228 PolarHBondContact O-N 3.06Å; L224-I228 VanDerWaalsContact O-N 3.15Å
225	A	84.9	Confident	85.9	Confident	1 Å²	1	43.5 Å²	43.5	1%	0.008	25%	0.246	C	C	.	.	H	α-helix	trans	-60.3	-35.7	174.1	0	0	0	0	0	112.1	F31 L34 C35 I221 G222 L223 V227 I228 I229	F31-A225 HydrophobicContact CD2-CB 3.85Å; F31-A225 VanDerWaalsContact CD2-O 3.24Å; F31-A225 WeakPolarHBondContact CD2-O 3.33Å; F31-A225 HydrophobicContact CE2-CB 4Å; F31-A225 WeakPolarHBondContact CE2-O 3.47Å; L34-A225 HydrophobicContact CB-CB 3.82Å; L34-A225 HydrophobicContact CD1-CB 4.36Å; C35-A225 VanDerWaalsContact SG-CB 3.52Å; I221-A225 PolarHBondContact O-N 3.47Å; G222-A225 WeakPolarHBondContact O-CA 3.3Å; G222-A225 VanDerWaalsContact O-CB 3.26Å; G222-A225 WeakPolarHBondContact O-CB 3.18Å; G222-A225 PolarHBondContact O-N 3.43Å; G222-A225 VanDerWaalsContact O-N 3.09Å; L223-A225 VanDerWaalsContact C-N 3.29Å; L223-A225 PolarHBondContact O-N 3.12Å; A225-V227 VanDerWaalsContact C-N 3.33Å; A225-V227 PolarHBondContact O-N 3.16Å; A225-I228 PolarHBondContact O-N 3.24Å; A225-I229 PolarHBondContact O-N 3.14Å
226	L	80.8	Confident	85.6	Confident	40 Å²	40	43.2 Å²	43.2	21%	0.209	24%	0.244	C	C	.	.	H	α-helix	trans	-64	-35.8	174.2	-68.4	-177.5	0	0	0	113.3	R136 L139 G222 L223 L224 I229 G230	R136-L226 HydrophobicContact CB-CD1 4.16Å; R136-L226 HydrophobicContact CG-CD1 4.26Å; R136-L226 HydrophobicContact CG-CD2 4.22Å; L139-L226 HydrophobicContact CD1-CD1 3.47Å; L139-L226 VanDerWaalsContact CD1-CD1 3.47Å; L139-L226 HydrophobicContact CD1-CD2 4Å; L139-L226 HydrophobicContact CD1-CG 3.42Å; L139-L226 VanDerWaalsContact CD1-CG 3.42Å; G222-L226 PolarHBondContact O-N 3.31Å; G222-L226 VanDerWaalsContact O-N 3.11Å; L223-L226 HydrophobicContact CD1-CD1 4.02Å; L223-L226 WeakPolarHBondContact O-CB 3.39Å; L223-L226 PolarHBondContact O-N 3.35Å; L223-L226 VanDerWaalsContact O-N 3.12Å; L224-L226 VanDerWaalsContact C-N 3.26Å; L224-L226 PolarHBondContact O-N 3.2Å; L226-I229 HydrophobicContact CD2-CG2 4.45Å; L226-I229 VanDerWaalsContact O-CG2 3.31Å; L226-I229 WeakPolarHBondContact O-CG2 3.27Å; L226-G230 PolarHBondContact O-N 3.45Å
227	V	84	Confident	85.1	Confident	86 Å²	86	44.3 Å²	44.3	52%	0.521	25%	0.247	S	C	.	.	H	α-helix	trans	-64.8	-45.4	175.2	178.6	0	0	0	0	109.7	L223 L224 A225 G230 L231	L223-V227 PolarHBondContact O-N 2.95Å; L224-V227 WeakPolarHBondContact O-CB 3.48Å; L224-V227 PolarHBondContact O-N 2.71Å; L224-V227 VanDerWaalsContact O-N 3.11Å; A225-V227 VanDerWaalsContact C-N 3.33Å; A225-V227 PolarHBondContact O-N 3.16Å; V227-G230 PolarHBondContact O-N 3.26Å; V227-L231 WeakPolarHBondContact O-CG 3.32Å; V227-L231 PolarHBondContact O-N 3.45Å
228	I	84.8	Confident	84.5	Confident	32 Å²	32	45.4 Å²	45.4	16%	0.164	24%	0.244	C	C	.	.	H	α-helix	trans	-64.2	-47.1	-179.2	-59.9	-179	0	0	0	111.4	F31 L34 L224 A225 G230 L231 L232	F31-I228 HydrophobicContact CB-CB 4.38Å; F31-I228 HydrophobicContact CB-CG2 3.84Å; L34-I228 HydrophobicContact CD1-CD1 3.51Å; L224-I228 PolarHBondContact O-N 3.06Å; L224-I228 VanDerWaalsContact O-N 3.15Å; A225-I228 PolarHBondContact O-N 3.24Å; I228-G230 PolarHBondContact O-N 3.11Å; I228-L231 WeakPolarHBondContact O-CB 3.29Å; I228-L231 PolarHBondContact O-N 3.41Å; I228-L232 HydrophobicContact CG2-CD1 3.92Å; I228-L232 HydrophobicContact CG2-CG 4.3Å; I228-L232 WeakPolarHBondContact O-CG 3.37Å; I228-L232 PolarHBondContact O-N 3.02Å; I228-L232 VanDerWaalsContact O-N 3.1Å
229	I	82.3	Confident	84.2	Confident	46 Å²	46	45.7 Å²	45.7	24%	0.236	25%	0.245	C	C	.	.	H	α-helix	trans	-63.8	-31.1	179.6	-166.1	62	0	0	0	112.2	F31 Y175 A225 L226 L231 L232	F31-I229 HydrophobicContact CD1-CD1 4.14Å; F31-I229 HydrophobicContact CD2-CB 3.92Å; F31-I229 HydrophobicContact CE1-CD1 3.8Å; F31-I229 HydrophobicContact CE1-CG1 4.36Å; F31-I229 HydrophobicContact CE2-CB 3.61Å; F31-I229 HydrophobicContact CE2-CD1 4.39Å; F31-I229 HydrophobicContact CE2-CG1 4.18Å; F31-I229 HydrophobicContact CE2-CG2 4.09Å; F31-I229 HydrophobicContact CZ-CB 3.95Å; F31-I229 HydrophobicContact CZ-CD1 3.94Å; F31-I229 HydrophobicContact CZ-CG1 3.98Å; Y175-I229 HydrophobicContact CE1-CD1 4.41Å; Y175-I229 HydrophobicContact CE2-CD1 4.4Å; A225-I229 PolarHBondContact O-N 3.14Å; L226-I229 HydrophobicContact CD2-CG2 4.45Å; L226-I229 VanDerWaalsContact O-CG2 3.31Å; L226-I229 WeakPolarHBondContact O-CG2 3.27Å; I229-L231 PolarHBondContact O-N 3.35Å; I229-L232 HydrophobicContact CD1-CB 4.34Å; I229-L232 HydrophobicContact CD1-CD1 4.4Å; I229-L232 PolarHBondContact O-N 2.91Å
230	G	82.5	Confident	84	Confident	52 Å²	52	45.6 Å²	45.6	54%	0.536	25%	0.245	S	C	.	.	H	α-helix	trans	-63.7	-26.5	172.9	0	0	0	0	0	113.9	L226 V227 I228	L226-G230 PolarHBondContact O-N 3.45Å; V227-G230 PolarHBondContact O-N 3.26Å; I228-G230 PolarHBondContact O-N 3.11Å
231	L	84.2	Confident	83.6	Confident	112 Å²	112	46.3 Å²	46.3	59%	0.586	24%	0.242	S	C	*	.	H	α-helix	trans	-85.8	-28.7	176.2	-61.9	174.7	0	0	0	112.7	V227 I228 I229 R254	V227-L231 WeakPolarHBondContact O-CG 3.32Å; V227-L231 PolarHBondContact O-N 3.45Å; I228-L231 WeakPolarHBondContact O-CB 3.29Å; I228-L231 PolarHBondContact O-N 3.41Å; I229-L231 PolarHBondContact O-N 3.35Å; L231-R254 PolarHBondContact O-NH2 2.73Å
232	L	85.3	Confident	83.2	Confident	14 Å²	14	47.3 Å²	47.3	7%	0.073	25%	0.252	C	S	.	.	S	Bend	trans	-75.7	164.7	176	-64.6	174.1	0	0	0	111.2	Y24 A27 A28 F31 Y175 I228 I229	Y24-L232 HydrophobicContact CD2-CD2 3.98Å; Y24-L232 HydrophobicContact CE1-CD2 4.19Å; Y24-L232 HydrophobicContact CE2-CD2 3.57Å; Y24-L232 HydrophobicContact CG-CD2 4.45Å; A27-L232 HydrophobicContact CB-CD2 4.07Å; A28-L232 HydrophobicContact CB-CD1 4.24Å; F31-L232 HydrophobicContact CB-CD1 4.19Å; Y175-L232 HydrophobicContact CE1-CD1 4.27Å; Y175-L232 WeakPolarHBondContact OH-CB 3.33Å; I228-L232 HydrophobicContact CG2-CD1 3.92Å; I228-L232 HydrophobicContact CG2-CG 4.3Å; I228-L232 WeakPolarHBondContact O-CG 3.37Å; I228-L232 PolarHBondContact O-N 3.02Å; I228-L232 VanDerWaalsContact O-N 3.1Å; I229-L232 HydrophobicContact CD1-CB 4.34Å; I229-L232 HydrophobicContact CD1-CD1 4.4Å; I229-L232 PolarHBondContact O-N 2.91Å
233	K	85.5	Confident	83.2	Confident	79 Å²	79	49.7 Å²	49.7	34%	0.343	28%	0.277	S	S	.	.			trans	-112	153.5	172.9	-65.7	-60	177.5	-164.3	0	109.4	Y24 Y175 A251	Y24-K233 PolarHBondContact OH-N 3.41Å; Y24-K233 PolarHBondContact OH-O 3.43Å; Y175-K233 PolarHBondContact OH-O 2.96Å; K233-A251 HydrophobicContact CB-CB 3.89Å; K233-A251 HydrophobicContact CG-CB 4.47Å
234	E	84.7	Confident	83.4	Confident	95 Å²	95	48.9 Å²	48.9	44%	0.444	27%	0.269	S	S	.	.			trans	-54.8	153.1	169.9	-64	-58.5	161.8	0	0	111.3	W238 L239	E234-W238 HydrophobicContact CB-CE3 4.22Å; E234-W238 HydrophobicContact CB-CZ3 4.46Å; E234-W238 HydrophobicContact CG-CZ3 4.33Å; E234-L239 HydrophobicContact CB-CD1 4.07Å; E234-L239 HydrophobicContact CB-CD2 4.22Å; E234-L239 HydrophobicContact CB-CG 4.04Å
235	S	83.2	Confident	83.6	Confident	1 Å²	1	47.3 Å²	47.3	1%	0.007	26%	0.261	C	S	.	.			trans	-62	133.8	-177	81.6	0	0	0	0	110	E178 R237 W238 L239	E178-S235 WeakPolarHBondContact OE2-CB 3.37Å; E178-S235 PolarHBondContact OE2-OG 3.13Å; S235-R237 PolarHBondContact O-N 3.03Å; S235-W238 PolarHBondContact O-N 3.48Å; S235-W238 WeakPolarHBondContact OG-CB 3.48Å; S235-W238 PolarHBondContact OG-N 2.9Å; S235-L239 WeakPolarHBondContact O-CG 3.27Å; S235-L239 PolarHBondContact O-N 3.49Å
236	P	85.8	Confident	83.8	Confident	1 Å²	1	51.3 Å²	51.3	1%	0.006	29%	0.294	C	S	.	.	H	α-helix	trans	-59	-33.5	178.2	-23.9	33	0	0	0	112	I15 L239 V240 A251 I255	I15-P236 HydrophobicContact CG2-CB 4.04Å; P236-L239 PolarHBondContact O-N 3.21Å; P236-V240 WeakPolarHBondContact O-CG2 3.48Å; P236-V240 PolarHBondContact O-N 3.42Å; P236-A251 HydrophobicContact CG-CB 4.32Å; P236-I255 HydrophobicContact CG-CD1 3.74Å
237	R	82.3	Confident	84.3	Confident	54 Å²	54	54.8 Å²	54.8	20%	0.204	31%	0.309	C	S	.	.	H	α-helix	trans	-59.4	-55	174.6	-174.5	-179.7	-178.5	138	14.8	111.3	D14 E16 S235 L239 V240 Q241 T278	D14-R237 IonicContact OD1-NH1 3.48Å; D14-R237 IonicContact OD2-NH1 3.78Å; D14-R237 PolarHBondContact OD2-NH1 3.37Å; E16-R237 IonicContact OE1-CZ 2.72Å; E16-R237 IonicContact OE1-NH1 3.44Å; E16-R237 PolarHBondContact OE1-NH1 2.86Å; E16-R237 IonicContact OE2-NH1 3.84Å; S235-R237 PolarHBondContact O-N 3.03Å; R237-L239 VanDerWaalsContact C-N 3.28Å; R237-L239 PolarHBondContact O-N 3.17Å; R237-V240 PolarHBondContact O-N 3.11Å; R237-Q241 VanDerWaalsContact O-CG 3.29Å; R237-Q241 WeakPolarHBondContact O-CG 3.17Å; R237-Q241 PolarHBondContact O-N 3.35Å; R237-T278 HydrophobicContact CG-CG2 4.17Å
238	W	79.4	Confident	84.5	Confident	73 Å²	73	50.7 Å²	50.7	28%	0.277	29%	0.285	S	S	.	.	H	α-helix	trans	-59.9	-39.5	179.5	179.6	89.9	0	0	0	112.2	E234 S235 Q241 S242	E234-W238 HydrophobicContact CB-CE3 4.22Å; E234-W238 HydrophobicContact CB-CZ3 4.46Å; E234-W238 HydrophobicContact CG-CZ3 4.33Å; S235-W238 PolarHBondContact O-N 3.48Å; S235-W238 WeakPolarHBondContact OG-CB 3.48Å; S235-W238 PolarHBondContact OG-N 2.9Å; W238-Q241 PolarHBondContact O-N 2.96Å; W238-S242 VanDerWaalsContact O-CB 3.26Å; W238-S242 WeakPolarHBondContact O-CB 3.24Å; W238-S242 PolarHBondContact O-N 2.84Å; W238-S242 PolarHBondContact O-OG 3.04Å
239	L	84.3	Confident	84.8	Confident	6 Å²	6	52.3 Å²	52.3	3%	0.031	29%	0.289	C	S	.	.	H	α-helix	trans	-63.1	-43.8	177.2	-70.9	168.3	0	0	0	112.1	E234 S235 P236 R237 S242 G243 K244 Q247 A248 A251	E234-L239 HydrophobicContact CB-CD1 4.07Å; E234-L239 HydrophobicContact CB-CD2 4.22Å; E234-L239 HydrophobicContact CB-CG 4.04Å; S235-L239 WeakPolarHBondContact O-CG 3.27Å; S235-L239 PolarHBondContact O-N 3.49Å; P236-L239 PolarHBondContact O-N 3.21Å; R237-L239 VanDerWaalsContact C-N 3.28Å; R237-L239 PolarHBondContact O-N 3.17Å; L239-S242 PolarHBondContact O-N 3.14Å; L239-G243 PolarHBondContact O-N 2.89Å; L239-K244 HydrophobicContact CB-CB 4.48Å; L239-K244 HydrophobicContact CD2-CB 4.11Å; L239-K244 HydrophobicContact CD2-CD 4.05Å; L239-K244 WeakPolarHBondContact O-CA 3.29Å; L239-K244 PolarHBondContact O-N 3.25Å; L239-Q247 HydrophobicContact CD1-CB 4.27Å; L239-Q247 HydrophobicContact CD2-CB 4.08Å; L239-A248 HydrophobicContact CB-CB 3.58Å; L239-A248 HydrophobicContact CD1-CB 4.46Å; L239-A251 HydrophobicContact CD1-CB 3.83Å
240	V	85.1	Confident	85.3	Confident	1 Å²	1	57.8 Å²	57.8	1%	0.006	31%	0.311	C	S	.	.	H	α-helix	trans	-63.4	-45.3	174.6	170.4	0	0	0	0	111.1	I15 P236 R237 S242 G243 A248 V275 T278 K279	I15-V240 HydrophobicContact CD1-CB 4.34Å; I15-V240 HydrophobicContact CD1-CG2 3.89Å; P236-V240 WeakPolarHBondContact O-CG2 3.48Å; P236-V240 PolarHBondContact O-N 3.42Å; R237-V240 PolarHBondContact O-N 3.11Å; V240-S242 PolarHBondContact O-N 3.01Å; V240-G243 PolarHBondContact O-N 3.09Å; V240-A248 HydrophobicContact CG2-CB 3.55Å; V240-V275 HydrophobicContact CG1-CB 4.45Å; V240-V275 HydrophobicContact CG1-CG1 3.95Å; V240-V275 HydrophobicContact CG2-CG2 3.99Å; V240-T278 HydrophobicContact CB-CG2 4.17Å; V240-T278 HydrophobicContact CG1-CG2 3.81Å; V240-K279 HydrophobicContact CG1-CG 3.89Å
241	Q	79.6	Confident	85.6	Confident	65 Å²	65	55.5 Å²	55.5	30%	0.304	29%	0.287	S	S	.	.	H	α-helix	trans	-64.9	-28.6	179.1	-66.1	-171.6	-29	0	0	112.6	R237 W238 G243 T278 V282	R237-Q241 VanDerWaalsContact O-CG 3.29Å; R237-Q241 WeakPolarHBondContact O-CG 3.17Å; R237-Q241 PolarHBondContact O-N 3.35Å; W238-Q241 PolarHBondContact O-N 2.96Å; Q241-G243 VanDerWaalsContact C-N 3.27Å; Q241-G243 PolarHBondContact O-N 2.84Å; Q241-T278 HydrophobicContact CG-CG2 4.03Å; Q241-V282 HydrophobicContact CB-CG2 3.8Å; Q241-V282 HydrophobicContact CG-CG2 3.6Å
242	S	78.9	Confident	85.9	Confident	54 Å²	54	50.3 Å²	50.3	38%	0.378	26%	0.26	S	S	.	.	T	Hydrogen-bonded Turn	trans	-84.3	3.8	174.9	-57.7	0	0	0	0	113.5	W238 L239 V240 K244	W238-S242 VanDerWaalsContact O-CB 3.26Å; W238-S242 WeakPolarHBondContact O-CB 3.24Å; W238-S242 PolarHBondContact O-N 2.84Å; W238-S242 PolarHBondContact O-OG 3.04Å; L239-S242 PolarHBondContact O-N 3.14Å; V240-S242 PolarHBondContact O-N 3.01Å; S242-K244 VanDerWaalsContact C-N 3.28Å; S242-K244 PolarHBondContact O-N 3.44Å
243	G	82.4	Confident	86.2	Confident	52 Å²	52	51.5 Å²	51.5	54%	0.536	27%	0.266	S	S	.	.	T	Hydrogen-bonded Turn	trans	74.4	10.1	-178.5	0	0	0	0	0	115	L239 V240 Q241 D245	L239-G243 PolarHBondContact O-N 2.89Å; V240-G243 PolarHBondContact O-N 3.09Å; Q241-G243 VanDerWaalsContact C-N 3.27Å; Q241-G243 PolarHBondContact O-N 2.84Å; G243-D245 VanDerWaalsContact C-N 3.33Å; G243-D245 PolarHBondContact O-N 3.35Å
244	K	87.1	Confident	86.4	Confident	77 Å²	77	52.4 Å²	52.4	34%	0.335	27%	0.267	S	S	.	.			trans	-92.4	54.8	-179.4	-62.9	177.4	-178.6	170.3	0	111.4	L239 S242 A246 Q247 A248	L239-K244 HydrophobicContact CB-CB 4.48Å; L239-K244 HydrophobicContact CD2-CB 4.11Å; L239-K244 HydrophobicContact CD2-CD 4.05Å; L239-K244 WeakPolarHBondContact O-CA 3.29Å; L239-K244 PolarHBondContact O-N 3.25Å; S242-K244 VanDerWaalsContact C-N 3.28Å; S242-K244 PolarHBondContact O-N 3.44Å; K244-A246 PolarHBondContact O-N 2.61Å; K244-Q247 HydrophobicContact CB-CB 4.21Å; K244-Q247 HydrophobicContact CB-CG 4.4Å; K244-Q247 PolarHBondContact O-N 3.4Å; K244-A248 PolarHBondContact O-N 3.39Å
245	D	88.3	Confident	86.6	Confident	52 Å²	52	48 Å²	48	28%	0.278	25%	0.246	S	C	.	.	H	α-helix	trans	-57.9	-40.9	-170.2	-61.2	-23.6	0	0	0	114	G243 Q247 A248 R249 K279	G243-D245 VanDerWaalsContact C-N 3.33Å; G243-D245 PolarHBondContact O-N 3.35Å; D245-Q247 VanDerWaalsContact C-N 3.33Å; D245-Q247 PolarHBondContact O-N 2.85Å; D245-A248 WeakPolarHBondContact O-CB 3.49Å; D245-A248 PolarHBondContact O-N 2.93Å; D245-R249 PolarHBondContact O-N 3.02Å; D245-K279 VanDerWaalsContact OD1-CE 3.29Å; D245-K279 WeakPolarHBondContact OD1-CE 3.37Å; D245-K279 IonicContact OD1-NZ 3.94Å; D245-K279 PolarHBondContact OD1-NZ 3.42Å; D245-K279 WeakPolarHBondContact OD2-CE 3.15Å; D245-K279 IonicContact OD2-NZ 3.42Å; D245-K279 PolarHBondContact OD2-NZ 2.97Å
246	A	90.1	Very high	86.8	Confident	85 Å²	85	48.1 Å²	48.1	70%	0.702	25%	0.247	S	C	*	.	H	α-helix	trans	-64.2	-38.6	178.3	0	0	0	0	0	112.1	K244 K250	K244-A246 PolarHBondContact O-N 2.61Å; A246-K250 PolarHBondContact O-N 3.2Å; A246-K250 VanDerWaalsContact O-N 3.13Å
247	Q	90	Very high	87.1	Confident	113 Å²	113	56.5 Å²	56.5	53%	0.528	28%	0.278	S	S	.	.	H	α-helix	trans	-70	-38.9	175.5	-60.8	-175.9	20.6	0	0	110.6	L239 K244 D245 R249 K250 A251	L239-Q247 HydrophobicContact CD1-CB 4.27Å; L239-Q247 HydrophobicContact CD2-CB 4.08Å; K244-Q247 HydrophobicContact CB-CB 4.21Å; K244-Q247 HydrophobicContact CB-CG 4.4Å; K244-Q247 PolarHBondContact O-N 3.4Å; D245-Q247 VanDerWaalsContact C-N 3.33Å; D245-Q247 PolarHBondContact O-N 2.85Å; Q247-R249 VanDerWaalsContact C-N 3.34Å; Q247-R249 PolarHBondContact O-N 3.28Å; Q247-K250 PolarHBondContact O-N 2.86Å; Q247-A251 WeakPolarHBondContact O-CB 3.31Å; Q247-A251 PolarHBondContact O-N 2.95Å
248	A	88.9	Confident	87.4	Confident	0 Å²	0	57 Å²	57	0%	0	29%	0.288	C	S	.	.	H	α-helix	trans	-58.1	-46.4	175.2	0	0	0	0	0	111.6	L239 V240 K244 D245 K250 A251 Y252 W271	L239-A248 HydrophobicContact CB-CB 3.58Å; L239-A248 HydrophobicContact CD1-CB 4.46Å; V240-A248 HydrophobicContact CG2-CB 3.55Å; K244-A248 PolarHBondContact O-N 3.39Å; D245-A248 WeakPolarHBondContact O-CB 3.49Å; D245-A248 PolarHBondContact O-N 2.93Å; A248-K250 VanDerWaalsContact C-N 3.34Å; A248-K250 PolarHBondContact O-N 3.22Å; A248-A251 PolarHBondContact O-N 3.43Å; A248-Y252 WeakPolarHBondContact O-CB 3.34Å; A248-Y252 PolarHBondContact O-N 3.47Å; A248-W271 HydrophobicContact CB-CH2 4.45Å; A248-W271 HydrophobicContact CB-CZ2 4.08Å
249	R	92	Very high	87.9	Confident	67 Å²	67	54.2 Å²	54.2	25%	0.253	28%	0.278	S	S	.	.	H	α-helix	trans	-62.7	-41.1	177.3	-166.1	173.1	-171.5	175.8	4.8	111.6	D245 Q247 Y252 L253 T268 W271	D245-R249 PolarHBondContact O-N 3.02Å; Q247-R249 VanDerWaalsContact C-N 3.34Å; Q247-R249 PolarHBondContact O-N 3.28Å; R249-Y252 PolarHBondContact O-N 3Å; R249-L253 HydrophobicContact CG-CD1 4.33Å; R249-L253 WeakPolarHBondContact O-CB 3.47Å; R249-L253 VanDerWaalsContact O-CG 3.27Å; R249-L253 WeakPolarHBondContact O-CG 3.12Å; R249-L253 PolarHBondContact O-N 3.04Å; R249-T268 PolarHBondContact NH2-OG1 2.81Å; R249-W271 VanDerWaalsContact CA-CZ2 3.45Å; R249-W271 HydrophobicContact CB-CZ2 3.75Å; R249-W271 HydrophobicContact CG-CD2 4.37Å; R249-W271 HydrophobicContact CG-CZ2 4.26Å
250	K	92.1	Very high	88	Confident	160 Å²	160	62.4 Å²	62.4	70%	0.696	32%	0.316	S	S	*	.	H	α-helix	trans	-65	-41	176.5	-170.8	175.3	-177	174.6	0	112.3	A246 Q247 A248 R254	A246-K250 PolarHBondContact O-N 3.2Å; A246-K250 VanDerWaalsContact O-N 3.13Å; Q247-K250 PolarHBondContact O-N 2.86Å; A248-K250 VanDerWaalsContact C-N 3.34Å; A248-K250 PolarHBondContact O-N 3.22Å; K250-R254 WeakPolarHBondContact O-CB 3.47Å; K250-R254 PolarHBondContact O-N 2.91Å; K250-R254 VanDerWaalsContact O-N 3.1Å
251	A	89.3	Confident	88.1	Confident	4 Å²	4	65.4 Å²	65.4	3%	0.033	33%	0.329	C	S	.	.	H	α-helix	trans	-63.3	-50.4	175.3	0	0	0	0	0	110.8	K233 P236 L239 Q247 A248 L253 R254 I255	K233-A251 HydrophobicContact CB-CB 3.89Å; K233-A251 HydrophobicContact CG-CB 4.47Å; P236-A251 HydrophobicContact CG-CB 4.32Å; L239-A251 HydrophobicContact CD1-CB 3.83Å; Q247-A251 WeakPolarHBondContact O-CB 3.31Å; Q247-A251 PolarHBondContact O-N 2.95Å; A248-A251 PolarHBondContact O-N 3.43Å; A251-L253 PolarHBondContact O-N 3.13Å; A251-R254 WeakPolarHBondContact O-CB 3.28Å; A251-R254 PolarHBondContact O-N 3.36Å; A251-R254 VanDerWaalsContact O-N 3.1Å; A251-I255 WeakPolarHBondContact O-CG1 3.46Å; A251-I255 PolarHBondContact O-N 2.91Å
252	Y	90.6	Very high	88.4	Confident	4 Å²	4	65.7 Å²	65.7	2%	0.016	33%	0.331	C	S	.	.	H	α-helix	trans	-54.6	-49.3	176.2	169.6	-104.5	0	0	0	112.8	A248 R249 R254 I255 L256 H264 L266 W271	A248-Y252 WeakPolarHBondContact O-CB 3.34Å; A248-Y252 PolarHBondContact O-N 3.47Å; R249-Y252 PolarHBondContact O-N 3Å; Y252-R254 VanDerWaalsContact C-N 3.28Å; Y252-R254 PolarHBondContact O-N 3.31Å; Y252-I255 WeakPolarHBondContact O-CB 3.42Å; Y252-I255 PolarHBondContact O-N 3.38Å; Y252-L256 HydrophobicContact CD1-CD1 4.3Å; Y252-L256 HydrophobicContact CE1-CD1 3.57Å; Y252-L256 HydrophobicContact CE1-CG 4.39Å; Y252-L256 HydrophobicContact CE2-CD1 4.07Å; Y252-L256 HydrophobicContact CE2-CD2 4.48Å; Y252-L256 HydrophobicContact CE2-CG 4.18Å; Y252-L256 VanDerWaalsContact CZ-CD1 3.45Å; Y252-L256 PolarHBondContact O-N 2.87Å; Y252-L256 WeakPolarHBondContact OH-CD1 3.33Å; Y252-H264 PolarHBondContact OH-O 3.22Å; Y252-L266 WeakPolarHBondContact OH-CG 3.45Å; Y252-L266 PolarHBondContact OH-N 3.37Å; Y252-W271 AromaticContact CD1-CE3 3.92Å; Y252-W271 HydrophobicContact CD1-CE3 3.92Å; Y252-W271 HydrophobicContact CD1-CH2 4.31Å; Y252-W271 AromaticContact CD1-CZ3 3.55Å; Y252-W271 HydrophobicContact CD1-CZ3 3.55Å; Y252-W271 AromaticContact CD2-CZ3 3.9Å; Y252-W271 HydrophobicContact CD2-CZ3 3.9Å; Y252-W271 HydrophobicContact CE1-CE3 4.14Å; Y252-W271 HydrophobicContact CE1-CZ3 4.11Å; Y252-W271 HydrophobicContact CE2-CZ3 4.41Å; Y252-W271 HydrophobicContact CG-CE3 4.25Å; Y252-W271 AromaticContact CG-CH2 3.99Å; Y252-W271 HydrophobicContact CG-CH2 3.99Å; Y252-W271 AromaticContact CG-CZ3 3.42Å; Y252-W271 HydrophobicContact CG-CZ3 3.42Å; Y252-W271 VanDerWaalsContact CG-CZ3 3.42Å
253	L	91	Very high	88.6	Confident	38 Å²	38	74.6 Å²	74.6	20%	0.199	36%	0.357	C	S	.	.	H	α-helix	trans	-63.1	-34.3	178	-70.1	173.5	0	0	0	112.6	R249 A251 R257 M262 R265	R249-L253 HydrophobicContact CG-CD1 4.33Å; R249-L253 WeakPolarHBondContact O-CB 3.47Å; R249-L253 VanDerWaalsContact O-CG 3.27Å; R249-L253 WeakPolarHBondContact O-CG 3.12Å; R249-L253 PolarHBondContact O-N 3.04Å; A251-L253 PolarHBondContact O-N 3.13Å; L253-R257 WeakPolarHBondContact O-CB 3.33Å; L253-R257 PolarHBondContact O-N 2.98Å; L253-M262 HydrophobicContact CD2-CE 4.43Å; L253-R265 HydrophobicContact CD2-CG 3.95Å
254	R	89.4	Confident	88.6	Confident	99 Å²	99	76.6 Å²	76.6	37%	0.374	35%	0.351	S	S	.	.	H	α-helix	trans	-67.4	-42.2	174.8	-175.5	171	173.7	147.8	-9.5	111.4	L231 K250 A251 Y252 R257 V258	L231-R254 PolarHBondContact O-NH2 2.73Å; K250-R254 WeakPolarHBondContact O-CB 3.47Å; K250-R254 PolarHBondContact O-N 2.91Å; K250-R254 VanDerWaalsContact O-N 3.1Å; A251-R254 WeakPolarHBondContact O-CB 3.28Å; A251-R254 PolarHBondContact O-N 3.36Å; A251-R254 VanDerWaalsContact O-N 3.1Å; Y252-R254 VanDerWaalsContact C-N 3.28Å; Y252-R254 PolarHBondContact O-N 3.31Å; R254-R257 PolarHBondContact O-N 3.33Å; R254-V258 HydrophobicContact CG-CG2 4.45Å; R254-V258 WeakPolarHBondContact O-CG2 3.39Å; R254-V258 PolarHBondContact O-N 3.37Å
255	I	88.5	Confident	88.6	Confident	2 Å²	2	78.6 Å²	78.6	1%	0.01	36%	0.357	C	S	.	.	H	α-helix	trans	-58.9	-49.1	176.1	-64.8	168	0	0	0	110.2	L19 Y24 P236 A251 Y252 R257 V258 N259	L19-I255 HydrophobicContact CD2-CD1 3.88Å; L19-I255 HydrophobicContact CD2-CG2 3.89Å; Y24-I255 HydrophobicContact CD1-CB 4.42Å; Y24-I255 HydrophobicContact CD1-CD1 4.35Å; Y24-I255 HydrophobicContact CD1-CG1 3.81Å; Y24-I255 HydrophobicContact CD1-CG2 3.98Å; Y24-I255 HydrophobicContact CD2-CG1 4.03Å; Y24-I255 HydrophobicContact CE1-CD1 3.87Å; Y24-I255 HydrophobicContact CE1-CG1 3.61Å; Y24-I255 HydrophobicContact CE2-CG1 3.82Å; Y24-I255 HydrophobicContact CG-CB 4.37Å; Y24-I255 HydrophobicContact CG-CG1 4.02Å; Y24-I255 HydrophobicContact CG-CG2 4.09Å; P236-I255 HydrophobicContact CG-CD1 3.74Å; A251-I255 WeakPolarHBondContact O-CG1 3.46Å; A251-I255 PolarHBondContact O-N 2.91Å; Y252-I255 WeakPolarHBondContact O-CB 3.42Å; Y252-I255 PolarHBondContact O-N 3.38Å; I255-R257 VanDerWaalsContact C-N 3.32Å; I255-R257 PolarHBondContact O-N 3.27Å; I255-V258 PolarHBondContact O-N 2.8Å; I255-N259 WeakPolarHBondContact O-CB 3.44Å; I255-N259 PolarHBondContact O-N 3.39Å
256	L	89	Confident	88.4	Confident	4 Å²	4	77.4 Å²	77.4	2%	0.021	35%	0.35	C	S	.	.	H	α-helix	trans	-60.9	-39.4	177.4	-71.6	-176.3	0	0	0	113	Y20 Y252 N259 Q260 K261 M262 R265	Y20-L256 HydrophobicContact CD2-CD2 4.45Å; Y252-L256 HydrophobicContact CD1-CD1 4.3Å; Y252-L256 HydrophobicContact CE1-CD1 3.57Å; Y252-L256 HydrophobicContact CE1-CG 4.39Å; Y252-L256 HydrophobicContact CE2-CD1 4.07Å; Y252-L256 HydrophobicContact CE2-CD2 4.48Å; Y252-L256 HydrophobicContact CE2-CG 4.18Å; Y252-L256 VanDerWaalsContact CZ-CD1 3.45Å; Y252-L256 PolarHBondContact O-N 2.87Å; Y252-L256 WeakPolarHBondContact OH-CD1 3.33Å; L256-N259 PolarHBondContact O-N 3.38Å; L256-Q260 PolarHBondContact O-N 3.11Å; L256-Q260 VanDerWaalsContact O-N 3.11Å; L256-K261 HydrophobicContact CD2-CB 4.25Å; L256-K261 PolarHBondContact O-N 3.37Å; L256-M262 HydrophobicContact CB-SD 3.78Å; L256-R265 HydrophobicContact CD1-CB 4.01Å
257	R	90.4	Very high	88.3	Confident	176 Å²	176	78.8 Å²	78.8	66%	0.664	35%	0.346	S	S	*	.	H	α-helix	trans	-64.8	-48.1	178	-172.5	-179.9	-64.9	165.3	-1.9	111.7	L253 R254 I255 N259 Q260 M262	L253-R257 WeakPolarHBondContact O-CB 3.33Å; L253-R257 PolarHBondContact O-N 2.98Å; R254-R257 PolarHBondContact O-N 3.33Å; I255-R257 VanDerWaalsContact C-N 3.32Å; I255-R257 PolarHBondContact O-N 3.27Å; R257-N259 VanDerWaalsContact C-N 3.29Å; R257-N259 PolarHBondContact O-N 2.76Å; R257-Q260 PolarHBondContact O-N 2.93Å; R257-Q260 VanDerWaalsContact O-N 3.11Å; R257-M262 HydrophobicContact CB-CG 4.44Å; R257-M262 HydrophobicContact CB-SD 4.11Å
258	V	89	Confident	88.2	Confident	66 Å²	66	76.2 Å²	76.2	40%	0.4	34%	0.338	S	S	.	.	H	α-helix	trans	-63.4	-37.8	178.2	172.9	0	0	0	0	111	A23 Y24 R254 I255 Q260	A23-V258 HydrophobicContact CB-CG1 4.22Å; Y24-V258 HydrophobicContact CD2-CB 4.44Å; Y24-V258 HydrophobicContact CD2-CG1 4.43Å; R254-V258 HydrophobicContact CG-CG2 4.45Å; R254-V258 WeakPolarHBondContact O-CG2 3.39Å; R254-V258 PolarHBondContact O-N 3.37Å; I255-V258 PolarHBondContact O-N 2.8Å; V258-Q260 PolarHBondContact O-N 3.32Å
259	N	89.2	Confident	88.1	Confident	13 Å²	13	82.3 Å²	82.3	7%	0.07	37%	0.371	C	S	.	.	T	Hydrogen-bonded Turn	trans	-79.8	1.6	176.9	-71.2	-10.6	0	0	0	114.3	Y20 G22 A23 Y24 Q25 I255 L256 R257 K261	Y20-N259 PolarHBondContact O-ND2 3.41Å; G22-N259 WeakPolarHBondContact CA-OD1 3.4Å; A23-N259 PolarHBondContact N-OD1 3.12Å; A23-N259 VanDerWaalsContact N-OD1 3.13Å; Y24-N259 WeakPolarHBondContact CB-OD1 3.32Å; Y24-N259 PolarHBondContact N-OD1 2.9Å; Q25-N259 PolarHBondContact NE2-ND2 3.32Å; Q25-N259 PolarHBondContact OE1-ND2 3.16Å; Q25-N259 PolarHBondContact OE1-OD1 3.13Å; I255-N259 WeakPolarHBondContact O-CB 3.44Å; I255-N259 PolarHBondContact O-N 3.39Å; L256-N259 PolarHBondContact O-N 3.38Å; R257-N259 VanDerWaalsContact C-N 3.29Å; R257-N259 PolarHBondContact O-N 2.76Å; N259-K261 HydrophobicContact CB-CB 4.41Å; N259-K261 HydrophobicContact CB-CD 4.49Å; N259-K261 WeakPolarHBondContact O-CG 3.31Å; N259-K261 PolarHBondContact O-N 2.91Å; N259-K261 VanDerWaalsContact O-N 3.14Å
260	Q	87.9	Confident	87.8	Confident	179 Å²	179	83.7 Å²	83.7	84%	0.836	38%	0.38	S	S	*	.	T	Hydrogen-bonded Turn	trans	54.4	29.1	-175.7	-57.4	179.7	-8.1	0	0	113.8	L256 R257 V258	L256-Q260 PolarHBondContact O-N 3.11Å; L256-Q260 VanDerWaalsContact O-N 3.11Å; R257-Q260 PolarHBondContact O-N 2.93Å; R257-Q260 VanDerWaalsContact O-N 3.11Å; V258-Q260 PolarHBondContact O-N 3.32Å
261	K	86.9	Confident	87.6	Confident	64 Å²	64	76.7 Å²	76.7	28%	0.278	35%	0.349	S	S	.	.			trans	-112.6	27.6	-175.6	-78.4	177.1	-177.2	177.4	0	113	Y20 C21 L256 N259 R263 H264	Y20-K261 HydrophobicContact CD1-CD 4.39Å; Y20-K261 HydrophobicContact CD2-CD 4.08Å; Y20-K261 HydrophobicContact CG-CD 3.69Å; C21-K261 PolarHBondContact O-NZ 2.88Å; L256-K261 HydrophobicContact CD2-CB 4.25Å; L256-K261 PolarHBondContact O-N 3.37Å; N259-K261 HydrophobicContact CB-CB 4.41Å; N259-K261 HydrophobicContact CB-CD 4.49Å; N259-K261 WeakPolarHBondContact O-CG 3.31Å; N259-K261 PolarHBondContact O-N 2.91Å; N259-K261 VanDerWaalsContact O-N 3.14Å; K261-R263 PolarHBondContact O-N 3.42Å; K261-H264 PolarHBondContact O-N 2.96Å
262	M	85.9	Confident	87.6	Confident	70 Å²	70	81.4 Å²	81.4	35%	0.345	37%	0.371	S	S	.	.	G	3₁₀ helix	trans	-55.9	-22.7	177.1	-74	-63.3	-59.8	0	0	113.8	L253 L256 R257 H264 R265	L253-M262 HydrophobicContact CD2-CE 4.43Å; L256-M262 HydrophobicContact CB-SD 3.78Å; R257-M262 HydrophobicContact CB-CG 4.44Å; R257-M262 HydrophobicContact CB-SD 4.11Å; M262-H264 PolarHBondContact O-N 3.45Å; M262-R265 WeakPolarHBondContact O-CB 3.44Å; M262-R265 PolarHBondContact O-N 2.92Å; M262-R265 VanDerWaalsContact O-N 3.17Å
263	R	83.8	Confident	87.4	Confident	242 Å²	242	83.5 Å²	83.5	91%	0.913	39%	0.389	S	S	*	.	G	3₁₀ helix	trans	-61.8	-25.6	173.5	-67.5	-176	179.3	172.8	0.5	113.6	K261 R265	K261-R263 PolarHBondContact O-N 3.42Å; R263-R265 VanDerWaalsContact C-N 3.32Å
264	H	82.3	Confident	87.2	Confident	93 Å²	93	81.7 Å²	81.7	43%	0.431	38%	0.38	S	S	.	.	G	3₁₀ helix	trans	-95.4	18.9	177.5	-59.2	-70.9	0	0	0	112.9	Y20 Y252 K261 M262 L266	Y20-H264 HydrophobicContact CD2-CB 4.3Å; Y20-H264 HydrophobicContact CE2-CB 3.38Å; Y20-H264 AromaticContact CE2-CD2 3.89Å; Y20-H264 AromaticContact CE2-CG 3.63Å; Y20-H264 AromaticContact CZ-CD2 3.9Å; Y20-H264 AromaticContact CZ-CG 3.6Å; Y20-H264 AromaticContact CZ-ND1 3.89Å; Y20-H264 PolarHBondContact OH-ND1 3.43Å; Y252-H264 PolarHBondContact OH-O 3.22Å; K261-H264 PolarHBondContact O-N 2.96Å; M262-H264 PolarHBondContact O-N 3.45Å; H264-L266 PolarHBondContact O-N 2.93Å
265	R	86.3	Confident	87	Confident	119 Å²	119	77.5 Å²	77.5	45%	0.449	37%	0.365	S	S	.	.	P	Polyproline II helix	trans	-62.5	125.4	176.3	174.4	-173.9	178	-174.1	2.2	109.3	L253 L256 M262 R263	L253-R265 HydrophobicContact CD2-CG 3.95Å; L256-R265 HydrophobicContact CD1-CB 4.01Å; M262-R265 WeakPolarHBondContact O-CB 3.44Å; M262-R265 PolarHBondContact O-N 2.92Å; M262-R265 VanDerWaalsContact O-N 3.17Å; R263-R265 VanDerWaalsContact C-N 3.32Å
266	L	84.9	Confident	86.9	Confident	27 Å²	27	82.8 Å²	82.8	14%	0.141	39%	0.39	C	S	.	.	P	Polyproline II helix	trans	-62.4	136.4	170.3	-65.4	170.6	0	0	0	111.3	T18 Y252 H264 E270 W271 V274	T18-L266 HydrophobicContact CG2-CD1 4.21Å; Y252-L266 WeakPolarHBondContact OH-CG 3.45Å; Y252-L266 PolarHBondContact OH-N 3.37Å; H264-L266 PolarHBondContact O-N 2.93Å; L266-E270 WeakPolarHBondContact CA-OE2 3.49Å; L266-E270 HydrophobicContact CB-CB 4.08Å; L266-E270 HydrophobicContact CD2-CB 3.87Å; L266-E270 HydrophobicContact CG-CB 4.46Å; L266-W271 HydrophobicContact CB-CB 4.4Å; L266-W271 HydrophobicContact CD1-CE3 4.14Å; L266-V274 HydrophobicContact CD1-CG2 4.01Å
267	N	87.9	Confident	86.5	Confident	115 Å²	115	83.3 Å²	83.3	62%	0.615	40%	0.395	S	S	*	.	P	Polyproline II helix	trans	-66	164.5	167.8	-75.2	-22	0	0	0	110.4	N269 E270 W271	N267-N269 VanDerWaalsContact C-N 3.32Å; N267-N269 PolarHBondContact O-N 3.18Å; N267-E270 HydrophobicContact CB-CG 4.43Å; N267-E270 PolarHBondContact N-OE2 3.1Å; N267-E270 PolarHBondContact O-N 3.21Å; N267-W271 WeakPolarHBondContact O-CB 3.48Å; N267-W271 PolarHBondContact O-N 3.36Å
268	T	87	Confident	86	Confident	59 Å²	59	75.1 Å²	75.1	36%	0.362	37%	0.365	S	S	.	.	H	α-helix	trans	-57.3	-43.4	-175.2	-59.3	0	0	0	0	112.3	R249 E270 W271 E272	R249-T268 PolarHBondContact NH2-OG1 2.81Å; T268-E270 PolarHBondContact O-N 2.9Å; T268-W271 WeakPolarHBondContact O-CB 3.3Å; T268-W271 PolarHBondContact O-N 3.46Å; T268-E272 WeakPolarHBondContact CG2-OE1 3.29Å; T268-E272 WeakPolarHBondContact O-CG 3.28Å; T268-E272 PolarHBondContact O-N 3.48Å
269	N	86.7	Confident	85.7	Confident	128 Å²	128	76.2 Å²	76.2	68%	0.684	36%	0.364	S	S	*	.	H	α-helix	trans	-65.6	-39.8	179.2	-57.9	3.1	0	0	0	112.4	N267 E272 A273	N267-N269 VanDerWaalsContact C-N 3.32Å; N267-N269 PolarHBondContact O-N 3.18Å; N269-E272 PolarHBondContact O-N 3.4Å; N269-A273 PolarHBondContact O-N 2.91Å
270	E	86.8	Confident	84.9	Confident	96 Å²	96	84 Å²	84	45%	0.449	39%	0.393	S	S	.	.	H	α-helix	trans	-68.1	-39.8	177.4	-59.9	174.2	141.6	0	0	110.9	L266 N267 T268 A273 V274	L266-E270 WeakPolarHBondContact CA-OE2 3.49Å; L266-E270 HydrophobicContact CB-CB 4.08Å; L266-E270 HydrophobicContact CD2-CB 3.87Å; L266-E270 HydrophobicContact CG-CB 4.46Å; N267-E270 HydrophobicContact CB-CG 4.43Å; N267-E270 PolarHBondContact N-OE2 3.1Å; N267-E270 PolarHBondContact O-N 3.21Å; T268-E270 PolarHBondContact O-N 2.9Å; E270-A273 PolarHBondContact O-N 3.46Å; E270-V274 WeakPolarHBondContact O-CB 3.36Å; E270-V274 WeakPolarHBondContact O-CG2 3.46Å; E270-V274 PolarHBondContact O-N 2.68Å
271	W	87.9	Confident	83.9	Confident	13 Å²	13	77.7 Å²	77.7	5%	0.049	37%	0.372	C	S	.	.	H	α-helix	trans	-61.7	-44.2	174.3	177.3	-96.3	0	0	0	111.6	A248 R249 Y252 L266 N267 T268 V274 V275	A248-W271 HydrophobicContact CB-CH2 4.45Å; A248-W271 HydrophobicContact CB-CZ2 4.08Å; R249-W271 VanDerWaalsContact CA-CZ2 3.45Å; R249-W271 HydrophobicContact CB-CZ2 3.75Å; R249-W271 HydrophobicContact CG-CD2 4.37Å; R249-W271 HydrophobicContact CG-CZ2 4.26Å; Y252-W271 AromaticContact CD1-CE3 3.92Å; Y252-W271 HydrophobicContact CD1-CE3 3.92Å; Y252-W271 HydrophobicContact CD1-CH2 4.31Å; Y252-W271 AromaticContact CD1-CZ3 3.55Å; Y252-W271 HydrophobicContact CD1-CZ3 3.55Å; Y252-W271 AromaticContact CD2-CZ3 3.9Å; Y252-W271 HydrophobicContact CD2-CZ3 3.9Å; Y252-W271 HydrophobicContact CE1-CE3 4.14Å; Y252-W271 HydrophobicContact CE1-CZ3 4.11Å; Y252-W271 HydrophobicContact CE2-CZ3 4.41Å; Y252-W271 HydrophobicContact CG-CE3 4.25Å; Y252-W271 AromaticContact CG-CH2 3.99Å; Y252-W271 HydrophobicContact CG-CH2 3.99Å; Y252-W271 AromaticContact CG-CZ3 3.42Å; Y252-W271 HydrophobicContact CG-CZ3 3.42Å; Y252-W271 VanDerWaalsContact CG-CZ3 3.42Å; L266-W271 HydrophobicContact CB-CB 4.4Å; L266-W271 HydrophobicContact CD1-CE3 4.14Å; N267-W271 WeakPolarHBondContact O-CB 3.48Å; N267-W271 PolarHBondContact O-N 3.36Å; T268-W271 WeakPolarHBondContact O-CB 3.3Å; T268-W271 PolarHBondContact O-N 3.46Å; W271-V274 PolarHBondContact O-N 2.96Å; W271-V275 HydrophobicContact CD2-CG2 4.3Å; W271-V275 HydrophobicContact CG-CG2 4.46Å; W271-V275 HydrophobicContact CZ2-CG2 4.05Å; W271-V275 WeakPolarHBondContact O-CB 3.35Å; W271-V275 VanDerWaalsContact O-CG2 3.24Å; W271-V275 WeakPolarHBondContact O-CG2 3.42Å; W271-V275 PolarHBondContact O-N 2.91Å
272	E	88.2	Confident	82.8	Confident	102 Å²	102	77.8 Å²	77.8	48%	0.477	38%	0.377	S	S	.	.	H	α-helix	trans	-62.8	-43.5	176.5	-75.1	169.6	-171.7	0	0	111.9	T268 N269 V274 V275 E276	T268-E272 WeakPolarHBondContact CG2-OE1 3.29Å; T268-E272 WeakPolarHBondContact O-CG 3.28Å; T268-E272 PolarHBondContact O-N 3.48Å; N269-E272 PolarHBondContact O-N 3.4Å; E272-V274 VanDerWaalsContact C-N 3.33Å; E272-V274 PolarHBondContact O-N 2.89Å; E272-V275 PolarHBondContact O-N 3.41Å; E272-E276 WeakPolarHBondContact O-CB 3.14Å; E272-E276 WeakPolarHBondContact O-CG 3.33Å; E272-E276 PolarHBondContact O-N 3.49Å
273	A	86.7	Confident	81.4	Confident	48 Å²	48	76.4 Å²	76.4	40%	0.397	37%	0.372	S	S	.	.	H	α-helix	trans	-60.4	-41.6	175.3	0	0	0	0	0	112.4	N269 E270 G277	N269-A273 PolarHBondContact O-N 2.91Å; E270-A273 PolarHBondContact O-N 3.46Å; A273-G277 PolarHBondContact O-N 2.94Å
274	V	86	Confident	80.2	Confident	1 Å²	1	73 Å²	73	1%	0.006	37%	0.365	C	S	.	.	H	α-helix	trans	-66.4	-42.1	176	169.5	0	0	0	0	111.4	P13 I15 L266 E270 W271 E272 G277 T278	P13-V274 HydrophobicContact CB-CG2 3.9Å; P13-V274 HydrophobicContact CG-CG2 3.71Å; I15-V274 HydrophobicContact CB-CG1 4.18Å; I15-V274 HydrophobicContact CD1-CG1 4.17Å; I15-V274 HydrophobicContact CG1-CG1 3.16Å; L266-V274 HydrophobicContact CD1-CG2 4.01Å; E270-V274 WeakPolarHBondContact O-CB 3.36Å; E270-V274 WeakPolarHBondContact O-CG2 3.46Å; E270-V274 PolarHBondContact O-N 2.68Å; W271-V274 PolarHBondContact O-N 2.96Å; E272-V274 VanDerWaalsContact C-N 3.33Å; E272-V274 PolarHBondContact O-N 2.89Å; V274-G277 PolarHBondContact O-N 3.15Å; V274-T278 WeakPolarHBondContact O-CB 3.36Å; V274-T278 PolarHBondContact O-N 2.69Å; V274-T278 PolarHBondContact O-OG1 3.25Å
275	V	86.4	Confident	79.1	Confident	11 Å²	11	78.9 Å²	78.9	7%	0.067	39%	0.389	C	S	.	.	H	α-helix	trans	-62.8	-45.9	175.9	166.3	0	0	0	0	110.7	V240 W271 E272 T278 K279	V240-V275 HydrophobicContact CG1-CB 4.45Å; V240-V275 HydrophobicContact CG1-CG1 3.95Å; V240-V275 HydrophobicContact CG2-CG2 3.99Å; W271-V275 HydrophobicContact CD2-CG2 4.3Å; W271-V275 HydrophobicContact CG-CG2 4.46Å; W271-V275 HydrophobicContact CZ2-CG2 4.05Å; W271-V275 WeakPolarHBondContact O-CB 3.35Å; W271-V275 VanDerWaalsContact O-CG2 3.24Å; W271-V275 WeakPolarHBondContact O-CG2 3.42Å; W271-V275 PolarHBondContact O-N 2.91Å; E272-V275 PolarHBondContact O-N 3.41Å; V275-T278 PolarHBondContact O-N 2.91Å; V275-K279 HydrophobicContact CG1-CD 4Å; V275-K279 HydrophobicContact CG1-CG 4.4Å; V275-K279 WeakPolarHBondContact O-CB 3.32Å; V275-K279 WeakPolarHBondContact O-CG 3.4Å; V275-K279 PolarHBondContact O-N 2.82Å
276	E	85.3	Confident	78	Confident	113 Å²	113	76.2 Å²	76.2	53%	0.528	38%	0.379	S	S	.	.	H	α-helix	trans	-63.7	-40	176.2	-76.9	-175.1	175.4	0	0	112.6	E272 T278 K279 R280	E272-E276 WeakPolarHBondContact O-CB 3.14Å; E272-E276 WeakPolarHBondContact O-CG 3.33Å; E272-E276 PolarHBondContact O-N 3.49Å; E276-T278 VanDerWaalsContact C-N 3.34Å; E276-K279 PolarHBondContact O-N 3.04Å; E276-R280 WeakPolarHBondContact O-CB 3.39Å; E276-R280 WeakPolarHBondContact O-CG 3.24Å; E276-R280 PolarHBondContact O-N 3.1Å; E276-R280 PolarHBondContact O-NE 3.26Å
277	G	81.3	Confident	77.6	Confident	14 Å²	14	77.9 Å²	77.9	14%	0.144	39%	0.392	C	S	.	.	H	α-helix	trans	-60.3	-45	173.1	0	0	0	0	0	111.6	A273 V274 R280 A281	A273-G277 PolarHBondContact O-N 2.94Å; V274-G277 PolarHBondContact O-N 3.15Å; G277-R280 PolarHBondContact O-N 2.96Å; G277-A281 PolarHBondContact O-N 3.03Å; G277-A281 VanDerWaalsContact O-N 3.09Å
278	T	80.6	Confident	77.1	Confident	4 Å²	4	76.5 Å²	76.5	3%	0.025	38%	0.381	C	S	.	.	H	α-helix	trans	-67.2	-40.3	178.4	-54.3	0	0	0	0	112.2	I15 R237 V240 Q241 V274 V275 E276 A281 V282	I15-T278 HydrophobicContact CD1-CG2 3.96Å; I15-T278 VanDerWaalsContact CD1-OG1 3.26Å; I15-T278 WeakPolarHBondContact CD1-OG1 3.48Å; I15-T278 WeakPolarHBondContact CG1-OG1 3.22Å; R237-T278 HydrophobicContact CG-CG2 4.17Å; V240-T278 HydrophobicContact CB-CG2 4.17Å; V240-T278 HydrophobicContact CG1-CG2 3.81Å; Q241-T278 HydrophobicContact CG-CG2 4.03Å; V274-T278 WeakPolarHBondContact O-CB 3.36Å; V274-T278 PolarHBondContact O-N 2.69Å; V274-T278 PolarHBondContact O-OG1 3.25Å; V275-T278 PolarHBondContact O-N 2.91Å; E276-T278 VanDerWaalsContact C-N 3.34Å; T278-A281 CarbonylContact O-C 3.43Å; T278-A281 WeakPolarHBondContact O-CA 3.47Å; T278-A281 WeakPolarHBondContact O-CB 3.48Å; T278-A281 PolarHBondContact O-N 3.13Å; T278-V282 PolarHBondContact O-N 2.92Å
279	K	81.5	Confident	76.7	Confident	89 Å²	89	83.7 Å²	83.7	39%	0.387	40%	0.402	S	S	.	.	H	α-helix	trans	-66	-40.3	175.9	-77	179.4	179.8	177.4	0	111.9	V240 D245 V275 E276 A281 V282	V240-K279 HydrophobicContact CG1-CG 3.89Å; D245-K279 VanDerWaalsContact OD1-CE 3.29Å; D245-K279 WeakPolarHBondContact OD1-CE 3.37Å; D245-K279 IonicContact OD1-NZ 3.94Å; D245-K279 PolarHBondContact OD1-NZ 3.42Å; D245-K279 WeakPolarHBondContact OD2-CE 3.15Å; D245-K279 IonicContact OD2-NZ 3.42Å; D245-K279 PolarHBondContact OD2-NZ 2.97Å; V275-K279 HydrophobicContact CG1-CD 4Å; V275-K279 HydrophobicContact CG1-CG 4.4Å; V275-K279 WeakPolarHBondContact O-CB 3.32Å; V275-K279 WeakPolarHBondContact O-CG 3.4Å; V275-K279 PolarHBondContact O-N 2.82Å; E276-K279 PolarHBondContact O-N 3.04Å; K279-A281 PolarHBondContact O-N 2.96Å; K279-V282 VanDerWaalsContact O-CB 3.23Å; K279-V282 WeakPolarHBondContact O-CB 3.46Å; K279-V282 WeakPolarHBondContact O-CG2 3.37Å; K279-V282 PolarHBondContact O-N 3.39Å
280	R	72.5	Confident	76.6	Confident	177 Å²	177	81.8 Å²	81.8	67%	0.668	39%	0.389	S	S	*	.	H	α-helix	trans	-62	-30.4	172	-79.2	-177.8	-84.7	169.7	-13.1	112.4	E276 G277 V282	E276-R280 WeakPolarHBondContact O-CB 3.39Å; E276-R280 WeakPolarHBondContact O-CG 3.24Å; E276-R280 PolarHBondContact O-N 3.1Å; E276-R280 PolarHBondContact O-NE 3.26Å; G277-R280 PolarHBondContact O-N 2.96Å; R280-V282 VanDerWaalsContact C-N 3.3Å
281	A	67.5	Low	76.4	Confident	47 Å²	47	77.2 Å²	77.2	39%	0.388	37%	0.367	S	S	.	.	T	Hydrogen-bonded Turn	trans	-79.2	-6.3	172.8	0	0	0	0	0	114	G277 T278 K279 V283	G277-A281 PolarHBondContact O-N 3.03Å; G277-A281 VanDerWaalsContact O-N 3.09Å; T278-A281 CarbonylContact O-C 3.43Å; T278-A281 WeakPolarHBondContact O-CA 3.47Å; T278-A281 WeakPolarHBondContact O-CB 3.48Å; T278-A281 PolarHBondContact O-N 3.13Å; K279-A281 PolarHBondContact O-N 2.96Å; A281-V283 PolarHBondContact O-N 2.96Å
282	V	62.7	Low	76.4	Confident	65 Å²	65	81.3 Å²	81.3	39%	0.394	39%	0.385	S	S	.	.			trans	-67.5	102.7	172.6	177.7	0	0	0	0	108.1	Q241 T278 K279 R280	Q241-V282 HydrophobicContact CB-CG2 3.8Å; Q241-V282 HydrophobicContact CG-CG2 3.6Å; T278-V282 PolarHBondContact O-N 2.92Å; K279-V282 VanDerWaalsContact O-CB 3.23Å; K279-V282 WeakPolarHBondContact O-CB 3.46Å; K279-V282 WeakPolarHBondContact O-CG2 3.37Å; K279-V282 PolarHBondContact O-N 3.39Å; R280-V282 VanDerWaalsContact C-N 3.3Å
283	V	57.9	Low	76.1	Confident	41 Å²	41	79.2 Å²	79.2	25%	0.248	39%	0.391	C	S	.	.			trans	-77.9	136.9	176	-174.6	0	0	0	0	109.9	A281 K285 E484	A281-V283 PolarHBondContact O-N 2.96Å; V283-K285 PolarHBondContact O-N 2.95Å; V283-E484 VanDerWaalsContact CG1-OE2 3.28Å; V283-E484 WeakPolarHBondContact CG1-OE2 3.44Å
284	K	58	Low	76.2	Confident	172 Å²	172	80.7 Å²	80.7	75%	0.748	40%	0.395	S	S	*	.			trans	-42	134	171.5	-79.3	-172.1	177.5	-173.7	0	110.7	R286	K284-R286 PolarHBondContact O-N 2.88Å
285	K	58.6	Low	76.3	Confident	216 Å²	216	84.5 Å²	84.5	94%	0.939	43%	0.427	S	S	*	.			trans	-51.8	111.8	171.5	-73	-177	177.9	-179.2	0	109	V283	V283-K285 PolarHBondContact O-N 2.95Å
286	R	64.1	Low	76.5	Confident	63 Å²	63	90.2 Å²	90.2	24%	0.238	45%	0.451	C	S	.	.			trans	-102.1	146.8	173.8	-73.2	-170.7	-177.6	-160.7	-0.6	109.6	K284 H290 I424 E484	K284-R286 PolarHBondContact O-N 2.88Å; R286-H290 HydrophobicContact CB-CB 4.36Å; R286-I424 HydrophobicContact CB-CD1 3.62Å; R286-I424 WeakPolarHBondContact O-CD1 3.38Å; R286-E484 IonicContact CZ-OE1 3.67Å; R286-E484 IonicContact NE-OE1 3.59Å; R286-E484 IonicContact NH2-OE1 3.83Å; R286-E484 PolarHBondContact NH2-OE1 3.4Å
287	S	75.5	Confident	76.6	Confident	61 Å²	61	85.5 Å²	85.5	43%	0.427	43%	0.429	S	S	.	.			trans	-88.8	164.5	170.8	-175.3	0	0	0	0	111.6	W289 H290	S287-W289 PolarHBondContact O-N 3.37Å; S287-W289 VanDerWaalsContact O-N 3.14Å; S287-H290 PolarHBondContact O-CD2 3.47Å; S287-H290 PolarHBondContact O-N 2.86Å; S287-H290 VanDerWaalsContact O-N 3.08Å
288	F	76.9	Confident	77.2	Confident	87 Å²	87	85.9 Å²	85.9	38%	0.382	43%	0.432	S	S	.	.	G	3₁₀ helix	trans	-53.7	-31	176.8	-68.6	-60	0	0	0	113.2	H290 L291 I424 F428	F288-H290 PolarHBondContact O-N 3.14Å; F288-H290 VanDerWaalsContact O-N 3.13Å; F288-L291 HydrophobicContact CD1-CD1 4.32Å; F288-L291 VanDerWaalsContact O-CB 3.29Å; F288-L291 WeakPolarHBondContact O-CB 3.47Å; F288-L291 WeakPolarHBondContact O-CG 3.48Å; F288-L291 PolarHBondContact O-N 3.14Å; F288-I424 HydrophobicContact CD1-CG2 3.48Å; F288-I424 VanDerWaalsContact CD1-CG2 3.48Å; F288-I424 HydrophobicContact CE1-CG2 3.8Å; F288-I424 HydrophobicContact CG-CG2 4.41Å; F288-F428 HydrophobicContact CB-CD2 4.48Å; F288-F428 HydrophobicContact CD1-CB 3.84Å; F288-F428 AromaticContact CD1-CD2 3.94Å; F288-F428 HydrophobicContact CD1-CD2 3.94Å; F288-F428 HydrophobicContact CD1-CG 4.33Å; F288-F428 HydrophobicContact CE1-CB 3.91Å; F288-F428 HydrophobicContact CE1-CD2 4.47Å; F288-F428 HydrophobicContact CG-CD2 4.31Å
289	W	80.4	Confident	77.8	Confident	210 Å²	210	88.2 Å²	88.2	80%	0.795	45%	0.446	S	S	*	.	G	3₁₀ helix	trans	-56.7	-28.6	177.7	-62.8	111	0	0	0	113.7	S287 L291 F292	S287-W289 PolarHBondContact O-N 3.37Å; S287-W289 VanDerWaalsContact O-N 3.14Å; W289-L291 PolarHBondContact O-N 3.43Å; W289-F292 PolarHBondContact O-N 3.48Å
290	H	83.4	Confident	78.4	Confident	88 Å²	88	85.4 Å²	85.4	41%	0.407	43%	0.433	S	S	.	.	G	3₁₀ helix	trans	-68	-19.3	177.7	-71.6	-80.9	0	0	0	113.7	R286 S287 F288 F292 G293 L297 M421	R286-H290 HydrophobicContact CB-CB 4.36Å; S287-H290 PolarHBondContact O-CD2 3.47Å; S287-H290 PolarHBondContact O-N 2.86Å; S287-H290 VanDerWaalsContact O-N 3.08Å; F288-H290 PolarHBondContact O-N 3.14Å; F288-H290 VanDerWaalsContact O-N 3.13Å; H290-F292 PolarHBondContact O-N 2.91Å; H290-G293 PolarHBondContact O-N 2.82Å; H290-G293 VanDerWaalsContact O-N 3.14Å; H290-L297 VanDerWaalsContact O-CD2 3.25Å; H290-L297 WeakPolarHBondContact O-CD2 3.27Å; H290-M421 HydrophobicContact CB-CE 4.03Å; H290-M421 WeakPolarHBondContact O-CE 3.38Å
291	L	83	Confident	79.4	Confident	0 Å²	0	77 Å²	77	0%	0	40%	0.401	C	S	.	.	G	3₁₀ helix	trans	-64.1	-23.4	172.3	-63.1	172.2	0	0	0	112	F288 W289 L297 A298 T301 Y417 M421 I424 A425 F428	F288-L291 HydrophobicContact CD1-CD1 4.32Å; F288-L291 VanDerWaalsContact O-CB 3.29Å; F288-L291 WeakPolarHBondContact O-CB 3.47Å; F288-L291 WeakPolarHBondContact O-CG 3.48Å; F288-L291 PolarHBondContact O-N 3.14Å; W289-L291 PolarHBondContact O-N 3.43Å; L291-L297 CarbonylContact O-C 3.59Å; L291-L297 WeakPolarHBondContact O-CD2 3.4Å; L291-L297 VanDerWaalsContact O-CG 3.23Å; L291-L297 WeakPolarHBondContact O-CG 3.28Å; L291-A298 PolarHBondContact O-N 3.18Å; L291-T301 HydrophobicContact CB-CG2 4.1Å; L291-T301 HydrophobicContact CD1-CG2 4.26Å; L291-T301 PolarHBondContact O-OG1 3.42Å; L291-Y417 HydrophobicContact CD2-CD1 3.96Å; L291-Y417 HydrophobicContact CD2-CE1 3.66Å; L291-M421 HydrophobicContact CD2-CB 4.29Å; L291-M421 HydrophobicContact CD2-SD 4.02Å; L291-I424 HydrophobicContact CD1-CG2 4.17Å; L291-I424 HydrophobicContact CG-CG2 4.35Å; L291-A425 HydrophobicContact CD2-CB 3.75Å; L291-F428 HydrophobicContact CD1-CB 3.58Å; L291-F428 HydrophobicContact CD1-CD1 4Å; L291-F428 HydrophobicContact CD1-CD2 4.31Å; L291-F428 HydrophobicContact CD1-CG 3.71Å
292	F	87.6	Confident	80.7	Confident	98 Å²	98	80.1 Å²	80.1	43%	0.43	41%	0.411	S	S	.	.	G	3₁₀ helix	trans	-101.9	9.9	177.9	-61.9	-85.5	0	0	0	112.7	W289 H290 T294 A298 T301 F428	W289-F292 PolarHBondContact O-N 3.48Å; H290-F292 PolarHBondContact O-N 2.91Å; F292-T294 VanDerWaalsContact C-N 3.27Å; F292-T294 PolarHBondContact O-N 3.44Å; F292-A298 HydrophobicContact CD1-CB 3.9Å; F292-T301 HydrophobicContact CZ-CG2 4.19Å; F292-F428 HydrophobicContact CE2-CE1 4.34Å; F292-F428 HydrophobicContact CE2-CE2 4.42Å; F292-F428 AromaticContact CE2-CZ 3.93Å; F292-F428 HydrophobicContact CE2-CZ 3.93Å; F292-F428 HydrophobicContact CZ-CE1 4.13Å; F292-F428 AromaticContact CZ-CZ 3.89Å; F292-F428 HydrophobicContact CZ-CZ 3.89Å
293	G	82.8	Confident	82.3	Confident	58 Å²	58	77.9 Å²	77.9	60%	0.598	40%	0.397	S	S	*	.	S	Bend	trans	-67.2	-21.4	-173.7	0	0	0	0	0	115.1	H290	H290-G293 PolarHBondContact O-N 2.82Å; H290-G293 VanDerWaalsContact O-N 3.14Å
294	T	88.3	Confident	84.1	Confident	79 Å²	79	76 Å²	76	49%	0.485	39%	0.386	S	S	.	.	S	Bend	trans	-135.2	148.6	172.7	66.7	0	0	0	0	110.4	F292 K296 L297 A298	F292-T294 VanDerWaalsContact C-N 3.27Å; F292-T294 PolarHBondContact O-N 3.44Å; T294-K296 PolarHBondContact O-N 3.14Å; T294-K296 VanDerWaalsContact O-N 3.17Å; T294-L297 PolarHBondContact O-N 3.13Å; T294-L297 VanDerWaalsContact O-N 3.08Å; T294-L297 VanDerWaalsContact OG1-CB 3.23Å; T294-L297 WeakPolarHBondContact OG1-CB 3.27Å; T294-L297 PolarHBondContact OG1-N 2.9Å; T294-A298 WeakPolarHBondContact O-CB 3.31Å; T294-A298 PolarHBondContact O-N 3.35Å
295	A	88.4	Confident	85.8	Confident	82 Å²	82	68 Å²	68	68%	0.678	35%	0.351	S	S	*	.	H	α-helix	trans	-56	-35.7	179.9	0	0	0	0	0	113.1	T299	A295-T299 WeakPolarHBondContact O-CB 3.38Å; A295-T299 PolarHBondContact O-N 3.39Å; A295-T299 PolarHBondContact O-OG1 3.11Å
296	K	89.7	Confident	87.6	Confident	130 Å²	130	60.5 Å²	60.5	57%	0.565	32%	0.324	S	S	*	.	H	α-helix	trans	-64.9	-49.5	176.1	-174.1	-178.8	179.1	-170.8	0	111.4	T294 T299 Y300	T294-K296 PolarHBondContact O-N 3.14Å; T294-K296 VanDerWaalsContact O-N 3.17Å; K296-T299 PolarHBondContact O-N 3.44Å; K296-Y300 HydrophobicContact CD-CE2 4.21Å; K296-Y300 VanDerWaalsContact CE-CZ 3.44Å; K296-Y300 WeakPolarHBondContact CE-OH 3.5Å; K296-Y300 HydrophobicContact CG-CD2 4.35Å; K296-Y300 HydrophobicContact CG-CE1 4.28Å; K296-Y300 HydrophobicContact CG-CE2 3.8Å; K296-Y300 VanDerWaalsContact O-CG 3.29Å; K296-Y300 PolarHBondContact O-N 3.37Å
297	L	88.9	Confident	89.1	Confident	14 Å²	14	57.6 Å²	57.6	7%	0.073	31%	0.313	C	S	.	.	H	α-helix	trans	-67.9	-36.9	179.6	-169.5	70.4	0	0	0	112.2	H290 L291 T294 Y300 T301 Y417 M421	H290-L297 VanDerWaalsContact O-CD2 3.25Å; H290-L297 WeakPolarHBondContact O-CD2 3.27Å; L291-L297 CarbonylContact O-C 3.59Å; L291-L297 WeakPolarHBondContact O-CD2 3.4Å; L291-L297 VanDerWaalsContact O-CG 3.23Å; L291-L297 WeakPolarHBondContact O-CG 3.28Å; T294-L297 PolarHBondContact O-N 3.13Å; T294-L297 VanDerWaalsContact O-N 3.08Å; T294-L297 VanDerWaalsContact OG1-CB 3.23Å; T294-L297 WeakPolarHBondContact OG1-CB 3.27Å; T294-L297 PolarHBondContact OG1-N 2.9Å; L297-Y300 PolarHBondContact O-N 3.17Å; L297-T301 WeakPolarHBondContact O-CB 3.38Å; L297-T301 PolarHBondContact O-N 3.45Å; L297-T301 PolarHBondContact O-OG1 3.26Å; L297-Y417 HydrophobicContact CD1-CD1 3.6Å; L297-Y417 HydrophobicContact CD1-CE1 3.52Å; L297-Y417 HydrophobicContact CG-CE1 4.24Å; L297-M421 HydrophobicContact CD1-SD 4.4Å; L297-M421 HydrophobicContact CD2-CE 3.63Å; L297-M421 HydrophobicContact CD2-SD 3.52Å; L297-M421 VanDerWaalsContact CD2-SD 3.52Å; L297-M421 HydrophobicContact CG-SD 4.49Å
298	A	92.4	Very high	90.1	Very high	23 Å²	23	55.1 Å²	55.1	19%	0.19	30%	0.295	C	S	.	.	H	α-helix	trans	-61.8	-45	173	0	0	0	0	0	111	L291 F292 T294 Y300 T301 L302	L291-A298 PolarHBondContact O-N 3.18Å; F292-A298 HydrophobicContact CD1-CB 3.9Å; T294-A298 WeakPolarHBondContact O-CB 3.31Å; T294-A298 PolarHBondContact O-N 3.35Å; A298-Y300 PolarHBondContact O-N 2.87Å; A298-T301 PolarHBondContact O-N 3.13Å; A298-L302 WeakPolarHBondContact O-CB 3.39Å; A298-L302 PolarHBondContact O-N 2.94Å
299	T	93.8	Very high	90.9	Very high	53 Å²	53	52.9 Å²	52.9	33%	0.325	29%	0.285	S	S	.	.	H	α-helix	trans	-61.4	-45.2	176.1	-57.5	0	0	0	0	111.2	A295 K296 L302 V303 K472	A295-T299 WeakPolarHBondContact O-CB 3.38Å; A295-T299 PolarHBondContact O-N 3.39Å; A295-T299 PolarHBondContact O-OG1 3.11Å; K296-T299 PolarHBondContact O-N 3.44Å; T299-L302 PolarHBondContact O-N 3.37Å; T299-V303 HydrophobicContact CG2-CG2 4.42Å; T299-V303 WeakPolarHBondContact O-CB 3.47Å; T299-V303 VanDerWaalsContact O-CG2 3.29Å; T299-V303 WeakPolarHBondContact O-CG2 3.32Å; T299-V303 PolarHBondContact O-N 3.38Å; T299-K472 HydrophobicContact CG2-CB 4.08Å; T299-K472 HydrophobicContact CG2-CD 3.93Å; T299-K472 HydrophobicContact CG2-CG 3.94Å
300	Y	94	Very high	91.7	Very high	30 Å²	30	42.9 Å²	42.9	12%	0.118	25%	0.247	C	C	.	.	H	α-helix	trans	-61.1	-45.2	176	-69.2	-8.6	0	0	0	111.8	K296 L297 A298 V303 M304 L416 K472 I473	K296-Y300 HydrophobicContact CD-CE2 4.21Å; K296-Y300 VanDerWaalsContact CE-CZ 3.44Å; K296-Y300 WeakPolarHBondContact CE-OH 3.5Å; K296-Y300 HydrophobicContact CG-CD2 4.35Å; K296-Y300 HydrophobicContact CG-CE1 4.28Å; K296-Y300 HydrophobicContact CG-CE2 3.8Å; K296-Y300 VanDerWaalsContact O-CG 3.29Å; K296-Y300 PolarHBondContact O-N 3.37Å; L297-Y300 PolarHBondContact O-N 3.17Å; A298-Y300 PolarHBondContact O-N 2.87Å; Y300-V303 PolarHBondContact O-N 3.44Å; Y300-M304 VanDerWaalsContact O-CB 3.25Å; Y300-M304 WeakPolarHBondContact O-CB 3.35Å; Y300-M304 WeakPolarHBondContact O-CG 3.44Å; Y300-M304 PolarHBondContact O-N 2.89Å; Y300-L416 HydrophobicContact CD1-CD2 4.39Å; Y300-L416 HydrophobicContact CD2-CD1 3.62Å; Y300-L416 HydrophobicContact CD2-CD2 3.75Å; Y300-L416 HydrophobicContact CD2-CG 3.56Å; Y300-L416 HydrophobicContact CE2-CD1 3.51Å; Y300-L416 HydrophobicContact CE2-CD2 4.45Å; Y300-L416 HydrophobicContact CE2-CG 4Å; Y300-L416 HydrophobicContact CG-CD1 4.26Å; Y300-L416 HydrophobicContact CG-CD2 3.69Å; Y300-L416 HydrophobicContact CG-CG 4.07Å; Y300-K472 VanDerWaalsContact CE1-O 3.23Å; Y300-K472 WeakPolarHBondContact CE1-O 3.32Å; Y300-I473 HydrophobicContact CD1-CD1 4Å
301	T	93.7	Very high	92.3	Very high	0 Å²	0	38.8 Å²	38.8	0%	0	23%	0.228	C	C	.	.	H	α-helix	trans	-63.2	-44.3	178.6	-54.6	0	0	0	0	111.8	L291 F292 L297 A298 S305 Y417 F428	L291-T301 HydrophobicContact CB-CG2 4.1Å; L291-T301 HydrophobicContact CD1-CG2 4.26Å; L291-T301 PolarHBondContact O-OG1 3.42Å; F292-T301 HydrophobicContact CZ-CG2 4.19Å; L297-T301 WeakPolarHBondContact O-CB 3.38Å; L297-T301 PolarHBondContact O-N 3.45Å; L297-T301 PolarHBondContact O-OG1 3.26Å; A298-T301 PolarHBondContact O-N 3.13Å; T301-S305 VanDerWaalsContact O-CB 3.28Å; T301-S305 WeakPolarHBondContact O-CB 3.28Å; T301-S305 PolarHBondContact O-N 3.43Å; T301-S305 PolarHBondContact O-OG 2.91Å; T301-Y417 WeakPolarHBondContact CA-OH 3.36Å; T301-Y417 WeakPolarHBondContact CB-OH 3.39Å; T301-Y417 PolarHBondContact N-OH 3.31Å; T301-Y417 PolarHBondContact OG1-OH 2.88Å; T301-F428 HydrophobicContact CG2-CD1 3.73Å; T301-F428 HydrophobicContact CG2-CE1 3.67Å
302	L	95.2	Very high	92.8	Very high	113 Å²	113	39 Å²	39	59%	0.592	23%	0.23	S	C	*	.	H	α-helix	trans	-63.5	-50.2	178.1	-176.1	66.4	0	0	0	111.9	A298 T299 M304 S305 V306	A298-L302 WeakPolarHBondContact O-CB 3.39Å; A298-L302 PolarHBondContact O-N 2.94Å; T299-L302 PolarHBondContact O-N 3.37Å; L302-M304 PolarHBondContact O-N 3.45Å; L302-S305 PolarHBondContact O-N 2.95Å; L302-V306 WeakPolarHBondContact O-CG2 3.41Å; L302-V306 PolarHBondContact O-N 3.09Å
303	V	96.3	Very high	93.1	Very high	18 Å²	18	34.4 Å²	34.4	11%	0.109	21%	0.21	C	C	.	.	H	α-helix	trans	-63.7	-45	-178.3	171.9	0	0	0	0	110.8	T299 Y300 V306 S307 G468 K472 I473	T299-V303 HydrophobicContact CG2-CG2 4.42Å; T299-V303 WeakPolarHBondContact O-CB 3.47Å; T299-V303 VanDerWaalsContact O-CG2 3.29Å; T299-V303 WeakPolarHBondContact O-CG2 3.32Å; T299-V303 PolarHBondContact O-N 3.38Å; Y300-V303 PolarHBondContact O-N 3.44Å; V303-V306 PolarHBondContact O-N 3.4Å; V303-S307 WeakPolarHBondContact O-CB 3.34Å; V303-S307 PolarHBondContact O-N 2.84Å; V303-S307 PolarHBondContact O-OG 2.96Å; V303-S307 VanDerWaalsContact O-OG 3.13Å; V303-G468 WeakPolarHBondContact CG1-O 3.35Å; V303-K472 HydrophobicContact CG2-CB 3.89Å; V303-K472 HydrophobicContact CG2-CG 3.96Å; V303-I473 HydrophobicContact CB-CD1 4.24Å; V303-I473 HydrophobicContact CG1-CD1 3.97Å; V303-I473 HydrophobicContact CG1-CG1 3.77Å
304	M	94.5	Very high	93.7	Very high	0 Å²	0	31.9 Å²	31.9	0%	0	18%	0.182	C	C	.	.	H	α-helix	trans	-65.1	-41	177.9	-68	-56.6	-67.2	0	0	111.7	Y300 L302 V306 S307 M308 I409 V412 V413 L416 M429 F469 I473	Y300-M304 VanDerWaalsContact O-CB 3.25Å; Y300-M304 WeakPolarHBondContact O-CB 3.35Å; Y300-M304 WeakPolarHBondContact O-CG 3.44Å; Y300-M304 PolarHBondContact O-N 2.89Å; L302-M304 PolarHBondContact O-N 3.45Å; M304-V306 PolarHBondContact O-N 2.9Å; M304-S307 PolarHBondContact O-N 3.3Å; M304-M308 VanDerWaalsContact O-CB 3.28Å; M304-M308 WeakPolarHBondContact O-CB 3.23Å; M304-M308 WeakPolarHBondContact O-CG 3.19Å; M304-M308 PolarHBondContact O-N 3.05Å; M304-I409 HydrophobicContact CE-CG2 3.68Å; M304-V412 HydrophobicContact CE-CB 4.47Å; M304-V412 HydrophobicContact CE-CG1 4.02Å; M304-V412 HydrophobicContact SD-CG1 4.33Å; M304-V413 HydrophobicContact CE-CG2 3.47Å; M304-V413 VanDerWaalsContact CE-CG2 3.47Å; M304-L416 HydrophobicContact CG-CD2 4.17Å; M304-M429 HydrophobicContact CB-CE 3.38Å; M304-M429 HydrophobicContact CB-SD 3.83Å; M304-M429 HydrophobicContact CG-CE 4.14Å; M304-F469 HydrophobicContact CE-CE2 4.38Å; M304-F469 HydrophobicContact SD-CD2 4.21Å; M304-F469 HydrophobicContact SD-CE2 3.78Å; M304-I473 HydrophobicContact CG-CD1 4.08Å; M304-I473 HydrophobicContact SD-CD1 3.93Å; M304-I473 HydrophobicContact SD-CG1 4.07Å
305	S	94.7	Very high	93.9	Very high	4 Å²	4	28.6 Å²	28.6	3%	0.028	16%	0.163	C	C	.	.	H	α-helix	trans	-60.9	-44	175.2	-71.5	0	0	0	0	112.3	T301 L302 M308 F309	T301-S305 VanDerWaalsContact O-CB 3.28Å; T301-S305 WeakPolarHBondContact O-CB 3.28Å; T301-S305 PolarHBondContact O-N 3.43Å; T301-S305 PolarHBondContact O-OG 2.91Å; L302-S305 PolarHBondContact O-N 2.95Å; S305-M308 PolarHBondContact O-N 3.21Å; S305-F309 VanDerWaalsContact O-CB 3.27Å; S305-F309 WeakPolarHBondContact O-CB 3.36Å; S305-F309 PolarHBondContact O-N 3.34Å
306	V	96	Very high	94.1	Very high	60 Å²	60	24.7 Å²	24.7	36%	0.364	13%	0.131	S	C	.	.	H	α-helix	trans	-66	-41.7	176.9	172.8	0	0	0	0	111.5	L302 V303 M304 F309 S310	L302-V306 WeakPolarHBondContact O-CG2 3.41Å; L302-V306 PolarHBondContact O-N 3.09Å; V303-V306 PolarHBondContact O-N 3.4Å; M304-V306 PolarHBondContact O-N 2.9Å; V306-F309 PolarHBondContact O-N 3.43Å; V306-S310 WeakPolarHBondContact O-CB 3.22Å; V306-S310 PolarHBondContact O-N 2.98Å; V306-S310 PolarHBondContact O-OG 3.25Å
307	S	96.7	Very high	94.2	Very high	1 Å²	1	18.8 Å²	18.8	1%	0.007	11%	0.106	C	C	.	.	H	α-helix	trans	-61.8	-44.9	175.6	-70.3	0	0	0	0	111.9	V303 M304 S310 L311 F465	V303-S307 WeakPolarHBondContact O-CB 3.34Å; V303-S307 PolarHBondContact O-N 2.84Å; V303-S307 PolarHBondContact O-OG 2.96Å; V303-S307 VanDerWaalsContact O-OG 3.13Å; M304-S307 PolarHBondContact O-N 3.3Å; S307-S310 PolarHBondContact O-N 3.29Å; S307-L311 WeakPolarHBondContact O-CB 3.32Å; S307-L311 PolarHBondContact O-N 2.66Å; S307-F465 VanDerWaalsContact CA-CD1 3.49Å; S307-F465 VanDerWaalsContact O-CD1 3.27Å; S307-F465 WeakPolarHBondContact O-CD1 3.46Å; S307-F465 WeakPolarHBondContact O-CE1 3.43Å
308	M	94.6	Very high	94.4	Very high	9 Å²	9	18.1 Å²	18.1	4%	0.044	10%	0.102	C	C	.	.	H	α-helix	trans	-64.7	-42.6	178.1	-71.4	-69.6	-149.9	0	0	112.4	M304 S305 S312 W406 I409 V413 M429 I433	M304-M308 VanDerWaalsContact O-CB 3.28Å; M304-M308 WeakPolarHBondContact O-CB 3.23Å; M304-M308 WeakPolarHBondContact O-CG 3.19Å; M304-M308 PolarHBondContact O-N 3.05Å; S305-M308 PolarHBondContact O-N 3.21Å; M308-S312 WeakPolarHBondContact O-CB 3.28Å; M308-S312 PolarHBondContact O-N 3.02Å; M308-W406 HydrophobicContact CE-CZ3 4.18Å; M308-W406 HydrophobicContact SD-CE3 4.24Å; M308-W406 HydrophobicContact SD-CH2 3.68Å; M308-W406 HydrophobicContact SD-CZ3 3.19Å; M308-W406 WeakPolarHBondContact SD-CZ3 3.48Å; M308-I409 HydrophobicContact CE-CG2 3.15Å; M308-I409 HydrophobicContact CG-CG2 4.35Å; M308-I409 HydrophobicContact SD-CG2 3.37Å; M308-I409 WeakPolarHBondContact SD-CG2 3.12Å; M308-V413 HydrophobicContact CE-CG2 3.58Å; M308-M429 HydrophobicContact CE-SD 4.16Å; M308-M429 HydrophobicContact CG-CB 4.29Å; M308-M429 HydrophobicContact CG-SD 4.3Å; M308-I433 HydrophobicContact CB-CD1 4.19Å; M308-I433 HydrophobicContact CB-CG1 3.78Å; M308-I433 HydrophobicContact CG-CD1 4.46Å; M308-I433 HydrophobicContact SD-CD1 3.99Å
309	F	95	Very high	94.5	Very high	40 Å²	40	17.3 Å²	17.3	18%	0.175	9%	0.094	C	C	.	.	H	α-helix	trans	-58.4	-52.2	173.2	179.9	-84.3	0	0	0	110.9	S305 V306 L311 S312 S313 F432 A435 A436 M439 L461	S305-F309 VanDerWaalsContact O-CB 3.27Å; S305-F309 WeakPolarHBondContact O-CB 3.36Å; S305-F309 PolarHBondContact O-N 3.34Å; V306-F309 PolarHBondContact O-N 3.43Å; F309-L311 PolarHBondContact O-N 3.46Å; F309-S312 PolarHBondContact O-N 3.09Å; F309-S313 PolarHBondContact O-N 3.07Å; F309-F432 HydrophobicContact CB-CB 4.25Å; F309-F432 HydrophobicContact CD2-CB 4.38Å; F309-F432 VanDerWaalsContact CD2-O 3.3Å; F309-F432 WeakPolarHBondContact CD2-O 2.93Å; F309-A435 HydrophobicContact CE2-CB 4.32Å; F309-A436 HydrophobicContact CB-CB 4.46Å; F309-A436 HydrophobicContact CD1-CB 4.24Å; F309-A436 HydrophobicContact CD2-CB 3.58Å; F309-A436 HydrophobicContact CE1-CB 4.38Å; F309-A436 HydrophobicContact CE2-CB 3.74Å; F309-A436 HydrophobicContact CG-CB 3.84Å; F309-A436 HydrophobicContact CZ-CB 4.15Å; F309-A436 WeakPolarHBondContact O-CB 3.41Å; F309-M439 HydrophobicContact CE1-SD 4.48Å; F309-M439 HydrophobicContact CE2-SD 4.13Å; F309-M439 HydrophobicContact CZ-SD 3.48Å; F309-M439 WeakPolarHBondContact CZ-SD 3.21Å; F309-L461 HydrophobicContact CD1-CD2 4.25Å; F309-L461 HydrophobicContact CE1-CD1 4.2Å; F309-L461 HydrophobicContact CE1-CD2 4.12Å
310	S	96	Very high	94.3	Very high	0 Å²	0	15.4 Å²	15.4	0%	0	8%	0.081	C	C	.	.	H	α-helix	trans	-59.3	-47.7	-179	-58	0	0	0	0	111.1	V306 S307 S312 S313 I314 L461	V306-S310 WeakPolarHBondContact O-CB 3.22Å; V306-S310 PolarHBondContact O-N 2.98Å; V306-S310 PolarHBondContact O-OG 3.25Å; S307-S310 PolarHBondContact O-N 3.29Å; S310-S312 VanDerWaalsContact C-N 3.32Å; S310-S312 PolarHBondContact O-N 3.35Å; S310-S313 PolarHBondContact O-N 3.19Å; S310-I314 WeakPolarHBondContact O-CB 3.3Å; S310-I314 VanDerWaalsContact O-CD1 3.3Å; S310-I314 WeakPolarHBondContact O-CD1 3.34Å; S310-I314 WeakPolarHBondContact O-CG1 3.31Å; S310-I314 PolarHBondContact O-N 2.86Å; S310-L461 PolarHBondContact OG-O 3.35Å
311	L	95.9	Very high	94.1	Very high	3 Å²	3	14.3 Å²	14.3	2%	0.016	8%	0.078	C	C	.	.	H	α-helix	trans	-62.3	-38.4	178.9	-176.7	61.3	0	0	0	112.8	S307 F309 S315 T402 I405 W406 I409 F465	S307-L311 WeakPolarHBondContact O-CB 3.32Å; S307-L311 PolarHBondContact O-N 2.66Å; F309-L311 PolarHBondContact O-N 3.46Å; L311-S315 VanDerWaalsContact O-CB 3.24Å; L311-S315 WeakPolarHBondContact O-CB 3.34Å; L311-S315 PolarHBondContact O-N 3.4Å; L311-S315 PolarHBondContact O-OG 3.25Å; L311-T402 HydrophobicContact CD1-CG2 4.2Å; L311-I405 HydrophobicContact CD1-CB 4.16Å; L311-I405 HydrophobicContact CD1-CD1 4.45Å; L311-I405 HydrophobicContact CD1-CG2 3.97Å; L311-I405 HydrophobicContact CD2-CB 4.27Å; L311-I405 HydrophobicContact CD2-CG2 3.65Å; L311-I405 HydrophobicContact CG-CG2 4.43Å; L311-W406 HydrophobicContact CB-CH2 4.41Å; L311-W406 HydrophobicContact CB-CZ2 4.16Å; L311-W406 HydrophobicContact CD2-CB 4.4Å; L311-W406 HydrophobicContact CD2-CD2 3.33Å; L311-W406 HydrophobicContact CD2-CE3 3.54Å; L311-W406 HydrophobicContact CD2-CG 3.79Å; L311-W406 HydrophobicContact CD2-CH2 3.92Å; L311-W406 HydrophobicContact CD2-CZ2 3.78Å; L311-W406 HydrophobicContact CD2-CZ3 3.86Å; L311-W406 HydrophobicContact CG-CD2 3.99Å; L311-W406 HydrophobicContact CG-CG 4.37Å; L311-W406 HydrophobicContact CG-CH2 4.27Å; L311-W406 HydrophobicContact CG-CZ2 3.76Å; L311-I409 HydrophobicContact CD2-CD1 3.91Å; L311-F465 HydrophobicContact CB-CE1 4.27Å
312	S	93.6	Very high	94.1	Very high	5 Å²	5	14.4 Å²	14.4	4%	0.035	8%	0.078	C	C	.	.	H	α-helix	trans	-67.4	-45.7	176.7	-173.7	0	0	0	0	111.8	M308 F309 S310 S315 T316 I433 S437	M308-S312 WeakPolarHBondContact O-CB 3.28Å; M308-S312 PolarHBondContact O-N 3.02Å; F309-S312 PolarHBondContact O-N 3.09Å; S310-S312 VanDerWaalsContact C-N 3.32Å; S310-S312 PolarHBondContact O-N 3.35Å; S312-S315 PolarHBondContact O-N 2.83Å; S312-T316 VanDerWaalsContact O-CB 3.31Å; S312-T316 WeakPolarHBondContact O-CB 2.83Å; S312-T316 PolarHBondContact O-N 3.32Å; S312-T316 PolarHBondContact O-OG1 3.04Å; S312-I433 PolarHBondContact OG-O 3.22Å; S312-S437 PolarHBondContact OG-OG 3.35Å
313	S	93.9	Very high	93.6	Very high	1 Å²	1	10.1 Å²	10.1	1%	0.007	6%	0.062	C	C	.	.	H	α-helix	trans	-57.9	-50.4	175.3	179.6	0	0	0	0	111.2	F309 S310 T316 T317 N458	F309-S313 PolarHBondContact O-N 3.07Å; S310-S313 PolarHBondContact O-N 3.19Å; S313-T316 PolarHBondContact O-N 3.43Å; S313-T317 WeakPolarHBondContact O-CB 3.35Å; S313-T317 PolarHBondContact O-N 3.45Å; S313-T317 PolarHBondContact O-OG1 2.82Å; S313-N458 PolarHBondContact OG-OD1 3.41Å
314	I	95.3	Very high	93	Very high	4 Å²	4	15.7 Å²	15.7	2%	0.021	9%	0.091	C	C	.	.	H	α-helix	trans	-60.3	-50.7	179.2	-68.4	161.5	0	0	0	110.7	S310 T316 T317 L318 V370 T402 N458	S310-I314 WeakPolarHBondContact O-CB 3.3Å; S310-I314 VanDerWaalsContact O-CD1 3.3Å; S310-I314 WeakPolarHBondContact O-CD1 3.34Å; S310-I314 WeakPolarHBondContact O-CG1 3.31Å; S310-I314 PolarHBondContact O-N 2.86Å; I314-T316 VanDerWaalsContact C-N 3.3Å; I314-T316 PolarHBondContact O-N 2.91Å; I314-T317 PolarHBondContact O-N 3.45Å; I314-L318 HydrophobicContact CG2-CD1 3.64Å; I314-L318 HydrophobicContact CG2-CG 4.36Å; I314-L318 WeakPolarHBondContact O-CB 3.44Å; I314-L318 VanDerWaalsContact O-CG 3.27Å; I314-L318 WeakPolarHBondContact O-CG 3.26Å; I314-L318 PolarHBondContact O-N 3.03Å; I314-V370 HydrophobicContact CD1-CG1 4.05Å; I314-V370 HydrophobicContact CG2-CG1 3.9Å; I314-T402 HydrophobicContact CG2-CG2 3.93Å; I314-N458 HydrophobicContact CG1-CB 3.92Å
315	S	93.5	Very high	92.7	Very high	10 Å²	10	16.6 Å²	16.6	7%	0.07	10%	0.096	C	C	.	.	H	α-helix	trans	-61.3	-40.4	-178.2	-62.8	0	0	0	0	112	L311 S312 L319 Y336	L311-S315 VanDerWaalsContact O-CB 3.24Å; L311-S315 WeakPolarHBondContact O-CB 3.34Å; L311-S315 PolarHBondContact O-N 3.4Å; L311-S315 PolarHBondContact O-OG 3.25Å; S312-S315 PolarHBondContact O-N 2.83Å; S315-L319 WeakPolarHBondContact O-CB 3.41Å; S315-L319 PolarHBondContact O-N 3.34Å; S315-Y336 PolarHBondContact O-OH 3.38Å
316	T	91.6	Very high	92.2	Very high	1 Å²	1	19.2 Å²	19.2	1%	0.006	11%	0.114	C	C	.	.	H	α-helix	trans	-73.1	-40	-178.8	-49.4	0	0	0	0	111.1	M43 S312 S313 I314 L319 Y320 A440	M43-T316 HydrophobicContact CE-CG2 3.99Å; M43-T316 WeakPolarHBondContact CE-OG1 3.41Å; S312-T316 VanDerWaalsContact O-CB 3.31Å; S312-T316 WeakPolarHBondContact O-CB 2.83Å; S312-T316 PolarHBondContact O-N 3.32Å; S312-T316 PolarHBondContact O-OG1 3.04Å; S313-T316 PolarHBondContact O-N 3.43Å; I314-T316 VanDerWaalsContact C-N 3.3Å; I314-T316 PolarHBondContact O-N 2.91Å; T316-L319 PolarHBondContact O-N 3.43Å; T316-Y320 HydrophobicContact CG2-CD2 3.72Å; T316-Y320 HydrophobicContact CG2-CE2 3.39Å; T316-Y320 VanDerWaalsContact O-CD2 3.22Å; T316-Y320 WeakPolarHBondContact O-CD2 3.45Å; T316-Y320 PolarHBondContact O-N 3.33Å; T316-A440 HydrophobicContact CG2-CB 3.28Å
317	T	92.4	Very high	91.7	Very high	6 Å²	6	19.7 Å²	19.7	4%	0.037	13%	0.131	C	C	.	.	H	α-helix	trans	-62.6	-47.4	175.3	-53.4	0	0	0	0	111.2	S313 I314 L319 Y320 S321 L443 P454 W455 N458	S313-T317 WeakPolarHBondContact O-CB 3.35Å; S313-T317 PolarHBondContact O-N 3.45Å; S313-T317 PolarHBondContact O-OG1 2.82Å; I314-T317 PolarHBondContact O-N 3.45Å; T317-L319 VanDerWaalsContact C-N 3.26Å; T317-L319 PolarHBondContact O-N 3.38Å; T317-Y320 PolarHBondContact O-N 3.1Å; T317-S321 WeakPolarHBondContact O-CB 3.44Å; T317-S321 PolarHBondContact O-N 2.89Å; T317-S321 PolarHBondContact O-OG 2.89Å; T317-L443 WeakPolarHBondContact OG1-CD1 3.47Å; T317-P454 HydrophobicContact CG2-CB 4.05Å; T317-W455 HydrophobicContact CG2-CZ3 4.34Å; T317-N458 WeakPolarHBondContact CB-ND2 3.09Å; T317-N458 WeakPolarHBondContact CG2-ND2 3.42Å; T317-N458 PolarHBondContact OG1-ND2 2.93Å
318	L	94.2	Very high	91.4	Very high	0 Å²	0	22.9 Å²	22.9	0%	0	15%	0.148	C	C	.	.	H	α-helix	trans	-62.5	-32.7	177.2	-71.7	168.1	0	0	0	112.8	I314 S321 Y336 V395 A398 A399 T402 W455	I314-L318 HydrophobicContact CG2-CD1 3.64Å; I314-L318 HydrophobicContact CG2-CG 4.36Å; I314-L318 WeakPolarHBondContact O-CB 3.44Å; I314-L318 VanDerWaalsContact O-CG 3.27Å; I314-L318 WeakPolarHBondContact O-CG 3.26Å; I314-L318 PolarHBondContact O-N 3.03Å; L318-S321 WeakPolarHBondContact CA-OG 3.17Å; L318-S321 PolarHBondContact O-OG 3.34Å; L318-Y336 HydrophobicContact CB-CE2 4.26Å; L318-V395 HydrophobicContact CD2-CB 4.46Å; L318-V395 HydrophobicContact CD2-CG1 4.04Å; L318-A398 HydrophobicContact CD1-CB 3.9Å; L318-A398 HydrophobicContact CD2-CB 4Å; L318-A399 HydrophobicContact CD1-CB 4.37Å; L318-T402 HydrophobicContact CD1-CG2 4.03Å; L318-W455 HydrophobicContact CD2-CZ3 3.98Å
319	L	93	Very high	91.3	Very high	6 Å²	6	23.2 Å²	23.2	3%	0.031	15%	0.15	C	C	.	.	H	α-helix	trans	-68.5	-46.9	176.1	178.5	65	0	0	0	110.9	M43 L47 L198 S315 T316 T317 L322 Y336	M43-L319 HydrophobicContact CG-CD2 4.3Å; L47-L319 HydrophobicContact CD2-CD1 4.26Å; L198-L319 HydrophobicContact CD2-CD1 4.19Å; L198-L319 HydrophobicContact CD2-CD2 4.35Å; S315-L319 WeakPolarHBondContact O-CB 3.41Å; S315-L319 PolarHBondContact O-N 3.34Å; T316-L319 PolarHBondContact O-N 3.43Å; T317-L319 VanDerWaalsContact C-N 3.26Å; T317-L319 PolarHBondContact O-N 3.38Å; L319-L322 HydrophobicContact CD1-CD1 4.11Å; L319-L322 WeakPolarHBondContact O-CB 3.41Å; L319-L322 WeakPolarHBondContact O-CD1 3.19Å; L319-L322 VanDerWaalsContact O-CG 3.26Å; L319-L322 WeakPolarHBondContact O-CG 3.49Å; L319-L322 PolarHBondContact O-N 3.3Å; L319-Y336 HydrophobicContact CD1-CD1 4.45Å; L319-Y336 HydrophobicContact CD1-CE1 3.86Å; L319-Y336 PolarHBondContact N-OH 3.42Å
320	Y	90.9	Very high	91.2	Very high	12 Å²	12	21.9 Å²	21.9	5%	0.047	14%	0.143	C	C	.	.	H	α-helix	trans	-75.3	-26	-178.6	-70.6	-59.3	0	0	0	113.6	M43 M46 L47 M113 T316 T317 L322 G323 A440 L444	M43-Y320 PolarHBondContact O-OH 3.06Å; M46-Y320 HydrophobicContact CB-CE1 4.22Å; L47-Y320 HydrophobicContact CB-CD1 4.17Å; L47-Y320 HydrophobicContact CB-CE1 4.24Å; M113-Y320 HydrophobicContact CE-CD1 3.92Å; M113-Y320 HydrophobicContact CE-CD2 3.91Å; M113-Y320 HydrophobicContact CE-CE1 3.52Å; M113-Y320 HydrophobicContact CE-CE2 3.46Å; M113-Y320 VanDerWaalsContact CE-CE2 3.46Å; M113-Y320 HydrophobicContact CE-CG 4.13Å; T316-Y320 HydrophobicContact CG2-CD2 3.72Å; T316-Y320 HydrophobicContact CG2-CE2 3.39Å; T316-Y320 VanDerWaalsContact O-CD2 3.22Å; T316-Y320 WeakPolarHBondContact O-CD2 3.45Å; T316-Y320 PolarHBondContact O-N 3.33Å; T317-Y320 PolarHBondContact O-N 3.1Å; Y320-L322 PolarHBondContact O-N 2.86Å; Y320-L322 VanDerWaalsContact O-N 3.08Å; Y320-G323 PolarHBondContact O-N 3.24Å; Y320-A440 HydrophobicContact CD2-CB 4.13Å; Y320-A440 HydrophobicContact CE2-CB 4.14Å; Y320-L444 HydrophobicContact CD2-CD1 4.17Å; Y320-L444 HydrophobicContact CG-CD1 3.95Å
321	S	90.2	Very high	91	Very high	7 Å²	7	26.5 Å²	26.5	5%	0.049	17%	0.168	C	C	.	.	T	Hydrogen-bonded Turn	trans	-63.9	-12.3	173.4	62.7	0	0	0	0	113.8	T317 L318 G323 D324 L325	T317-S321 WeakPolarHBondContact O-CB 3.44Å; T317-S321 PolarHBondContact O-N 2.89Å; T317-S321 PolarHBondContact O-OG 2.89Å; L318-S321 WeakPolarHBondContact CA-OG 3.17Å; L318-S321 PolarHBondContact O-OG 3.34Å; S321-G323 PolarHBondContact O-N 2.95Å; S321-D324 PolarHBondContact O-N 2.76Å; S321-L325 PolarHBondContact O-N 3.38Å
322	L	91.6	Very high	90.9	Very high	2 Å²	2	27 Å²	27	1%	0.01	17%	0.171	C	C	.	.	T	Hydrogen-bonded Turn	trans	-64	-26.8	174.4	-64.1	177.6	0	0	0	113	L47 L319 Y320 D324 L325 N332 Y336 F396	L47-L322 HydrophobicContact CD1-CB 4.08Å; L47-L322 HydrophobicContact CD2-CB 4.38Å; L47-L322 HydrophobicContact CD2-CD1 4.21Å; L319-L322 HydrophobicContact CD1-CD1 4.11Å; L319-L322 WeakPolarHBondContact O-CB 3.41Å; L319-L322 WeakPolarHBondContact O-CD1 3.19Å; L319-L322 VanDerWaalsContact O-CG 3.26Å; L319-L322 WeakPolarHBondContact O-CG 3.49Å; L319-L322 PolarHBondContact O-N 3.3Å; Y320-L322 PolarHBondContact O-N 2.86Å; Y320-L322 VanDerWaalsContact O-N 3.08Å; L322-D324 VanDerWaalsContact C-N 3.35Å; L322-L325 HydrophobicContact CD2-CD2 4.36Å; L322-N332 HydrophobicContact CD2-CB 4.47Å; L322-Y336 HydrophobicContact CD1-CD1 3.95Å; L322-Y336 HydrophobicContact CD1-CD2 3.92Å; L322-Y336 HydrophobicContact CD1-CE1 4.42Å; L322-Y336 HydrophobicContact CD1-CE2 4.33Å; L322-Y336 HydrophobicContact CD1-CG 3.68Å; L322-Y336 HydrophobicContact CD2-CD2 3.74Å; L322-Y336 HydrophobicContact CD2-CE2 4.4Å; L322-Y336 HydrophobicContact CD2-CG 4.1Å; L322-Y336 HydrophobicContact CG-CD2 4.18Å; L322-Y336 HydrophobicContact CG-CG 4.4Å; L322-F396 HydrophobicContact CD2-CE1 3.81Å
323	G	85.8	Confident	91	Very high	23 Å²	23	26.9 Å²	26.9	24%	0.237	17%	0.17	C	C	.	.	T	Hydrogen-bonded Turn	trans	-71.6	-30.2	176	0	0	0	0	0	112.9	Y320 S321	Y320-G323 PolarHBondContact O-N 3.24Å; S321-G323 PolarHBondContact O-N 2.95Å
324	D	84.1	Confident	91	Very high	136 Å²	136	28.9 Å²	28.9	73%	0.727	18%	0.182	S	C	*	.	T	Hydrogen-bonded Turn	trans	-90.7	-11.4	179.8	-59.2	-38.6	0	0	0	112.6	S321 L322	S321-D324 PolarHBondContact O-N 2.76Å; L322-D324 VanDerWaalsContact C-N 3.35Å
325	L	87	Confident	91	Very high	18 Å²	18	33.6 Å²	33.6	9%	0.094	20%	0.202	C	C	.	.	S	Bend	trans	-73.2	136.1	-177.5	-143	70.9	0	0	0	110.4	S321 L322 N332 T391 I392 V395 F396	S321-L325 PolarHBondContact O-N 3.38Å; L322-L325 HydrophobicContact CD2-CD2 4.36Å; L325-N332 PolarHBondContact O-ND2 3.07Å; L325-T391 HydrophobicContact CD1-CG2 4.11Å; L325-I392 HydrophobicContact CD1-CG1 4.15Å; L325-I392 HydrophobicContact CD2-CB 4.31Å; L325-I392 HydrophobicContact CD2-CG1 3.68Å; L325-I392 HydrophobicContact CD2-CG2 4.37Å; L325-I392 HydrophobicContact CG-CG1 3.63Å; L325-V395 HydrophobicContact CD1-CB 4.5Å; L325-V395 HydrophobicContact CD1-CG2 4.14Å; L325-F396 HydrophobicContact CD2-CE1 4.01Å; L325-F396 HydrophobicContact CD2-CZ 4.21Å
326	S	84.2	Confident	91.1	Very high	60 Å²	60	33.2 Å²	33.2	42%	0.42	20%	0.199	S	C	.	.	S	Bend	trans	-59.2	141.5	178.8	62.3	0	0	0	0	111.9	N332 P388 I392	S326-N332 PolarHBondContact O-ND2 2.71Å; S326-P388 WeakPolarHBondContact OG-CB 3.22Å; S326-I392 WeakPolarHBondContact OG-CD1 3.26Å
327	G	86.8	Confident	91.2	Very high	69 Å²	69	33.3 Å²	33.3	71%	0.711	20%	0.2	S	C	*	.	S	Bend	trans	106.4	-166.3	177.8	0	0	0	0	0	113.1
328	N	90.1	Very high	91.3	Very high	68 Å²	68	36.4 Å²	36.4	36%	0.364	22%	0.216	S	C	.	.			trans	-80.8	124.8	-177.8	-174.3	-37.7	0	0	0	110.7	Y330 L331 N332	N328-Y330 PolarHBondContact O-N 2.95Å; N328-Y330 WeakPolarHBondContact OD1-CB 3.21Å; N328-Y330 VanDerWaalsContact OD1-CD2 3.22Å; N328-Y330 WeakPolarHBondContact OD1-CD2 3.15Å; N328-Y330 PolarHBondContact OD1-N 3.42Å; N328-L331 HydrophobicContact CB-CB 4.29Å; N328-L331 HydrophobicContact CB-CD1 4.14Å; N328-L331 HydrophobicContact CB-CG 4.21Å; N328-L331 PolarHBondContact O-N 3.36Å; N328-L331 VanDerWaalsContact O-N 3.11Å; N328-N332 PolarHBondContact O-N 3.26Å
329	I	91.1	Very high	91.4	Very high	16 Å²	16	39.1 Å²	39.1	8%	0.082	23%	0.23	C	C	.	.	H	α-helix	trans	-55.3	-36	179.4	-168.7	170.8	0	0	0	113.2	L47 Y48 L51 S333	L47-I329 HydrophobicContact CD1-CD1 4.34Å; L47-I329 HydrophobicContact CG-CD1 4.27Å; Y48-I329 HydrophobicContact CD1-CD1 3.97Å; Y48-I329 HydrophobicContact CD1-CG1 4.43Å; Y48-I329 HydrophobicContact CE1-CD1 4.1Å; Y48-I329 HydrophobicContact CE1-CG1 4.07Å; Y48-I329 HydrophobicContact CE1-CG2 4.38Å; L51-I329 HydrophobicContact CD1-CD1 4.18Å; L51-I329 HydrophobicContact CD2-CD1 4.07Å; I329-S333 WeakPolarHBondContact O-CB 3.44Å; I329-S333 PolarHBondContact O-N 3.36Å; I329-S333 PolarHBondContact O-OG 3.3Å
330	Y	93.3	Very high	91.4	Very high	12 Å²	12	39.1 Å²	39.1	5%	0.047	23%	0.229	C	C	.	.	H	α-helix	trans	-69.2	-41.9	178.6	-58.5	-67.2	0	0	0	111.7	Y48 S91 F92 A205 F206 N328 T334	Y48-Y330 HydrophobicContact CD1-CE1 4.34Å; Y48-Y330 AromaticContact CE1-CD1 4Å; Y48-Y330 HydrophobicContact CE1-CD1 4Å; Y48-Y330 HydrophobicContact CE1-CE1 4.01Å; S91-Y330 PolarHBondContact O-OH 3.13Å; F92-Y330 WeakPolarHBondContact CB-OH 3.13Å; F92-Y330 WeakPolarHBondContact CD2-OH 3.23Å; A205-Y330 HydrophobicContact CB-CE1 4.15Å; F206-Y330 HydrophobicContact CB-CD1 3.93Å; F206-Y330 HydrophobicContact CB-CE1 4.07Å; F206-Y330 HydrophobicContact CB-CG 4.49Å; F206-Y330 HydrophobicContact CD2-CD1 4.2Å; F206-Y330 AromaticContact CD2-CD2 4Å; F206-Y330 HydrophobicContact CD2-CD2 4Å; F206-Y330 HydrophobicContact CD2-CE1 4.46Å; F206-Y330 HydrophobicContact CD2-CE2 4.26Å; F206-Y330 AromaticContact CD2-CG 3.95Å; F206-Y330 HydrophobicContact CD2-CG 3.95Å; N328-Y330 PolarHBondContact O-N 2.95Å; N328-Y330 WeakPolarHBondContact OD1-CB 3.21Å; N328-Y330 VanDerWaalsContact OD1-CD2 3.22Å; N328-Y330 WeakPolarHBondContact OD1-CD2 3.15Å; N328-Y330 PolarHBondContact OD1-N 3.42Å; Y330-T334 VanDerWaalsContact O-CB 3.27Å; Y330-T334 WeakPolarHBondContact O-CB 3.34Å; Y330-T334 PolarHBondContact O-N 3.46Å; Y330-T334 PolarHBondContact O-OG1 2.9Å
331	L	93.1	Very high	91.5	Very high	97 Å²	97	42.7 Å²	42.7	51%	0.508	24%	0.243	S	C	.	.	H	α-helix	trans	-66.4	-47.4	176	-70.7	178.4	0	0	0	110.6	N328 S333 T334 F335	N328-L331 HydrophobicContact CB-CB 4.29Å; N328-L331 HydrophobicContact CB-CD1 4.14Å; N328-L331 HydrophobicContact CB-CG 4.21Å; N328-L331 PolarHBondContact O-N 3.36Å; N328-L331 VanDerWaalsContact O-N 3.11Å; L331-S333 VanDerWaalsContact C-N 3.3Å; L331-S333 PolarHBondContact O-N 3.37Å; L331-T334 PolarHBondContact O-N 3.06Å; L331-F335 HydrophobicContact CB-CD2 4.4Å; L331-F335 HydrophobicContact CB-CE2 4.27Å; L331-F335 HydrophobicContact CD2-CE2 4.47Å; L331-F335 WeakPolarHBondContact O-CD2 3.48Å; L331-F335 PolarHBondContact O-N 2.92Å
332	N	93.9	Very high	91.7	Very high	15 Å²	15	44.8 Å²	44.8	8%	0.08	26%	0.257	C	S	.	.	H	α-helix	trans	-57.6	-45.2	177.9	-72.4	-13	0	0	0	111.1	L322 L325 S326 N328 Y336 F396	L322-N332 HydrophobicContact CD2-CB 4.47Å; L325-N332 PolarHBondContact O-ND2 3.07Å; S326-N332 PolarHBondContact O-ND2 2.71Å; N328-N332 PolarHBondContact O-N 3.26Å; N332-Y336 WeakPolarHBondContact O-CB 3.36Å; N332-Y336 PolarHBondContact O-N 3.06Å; N332-F396 HydrophobicContact CB-CZ 4.47Å
333	S	94	Very high	91.8	Very high	2 Å²	2	47 Å²	47	1%	0.014	27%	0.271	C	S	.	.	H	α-helix	trans	-69.6	-34.7	178.2	-55.8	0	0	0	0	113.3	Y48 V202 I329 L331 S337	Y48-S333 VanDerWaalsContact OH-CB 3.27Å; Y48-S333 WeakPolarHBondContact OH-CB 3.15Å; Y48-S333 PolarHBondContact OH-OG 3.34Å; V202-S333 VanDerWaalsContact CG2-CB 3.47Å; I329-S333 WeakPolarHBondContact O-CB 3.44Å; I329-S333 PolarHBondContact O-N 3.36Å; I329-S333 PolarHBondContact O-OG 3.3Å; L331-S333 VanDerWaalsContact C-N 3.3Å; L331-S333 PolarHBondContact O-N 3.37Å; S333-S337 WeakPolarHBondContact O-CB 3.24Å; S333-S337 PolarHBondContact O-N 3.33Å; S333-S337 PolarHBondContact O-OG 2.9Å
334	T	95.6	Very high	92	Very high	42 Å²	42	46 Å²	46	26%	0.258	26%	0.26	S	S	.	.	H	α-helix	trans	-66	-52.2	175.8	-61.4	0	0	0	0	110.6	L199 V202 Y330 L331 Y336 S337 L338	L199-T334 HydrophobicContact CD1-CG2 4.1Å; V202-T334 WeakPolarHBondContact CG1-OG1 3.35Å; Y330-T334 VanDerWaalsContact O-CB 3.27Å; Y330-T334 WeakPolarHBondContact O-CB 3.34Å; Y330-T334 PolarHBondContact O-N 3.46Å; Y330-T334 PolarHBondContact O-OG1 2.9Å; L331-T334 PolarHBondContact O-N 3.06Å; T334-Y336 PolarHBondContact O-N 3.47Å; T334-S337 PolarHBondContact O-N 3.14Å; T334-L338 HydrophobicContact CG2-CD1 3.78Å; T334-L338 HydrophobicContact CG2-CG 4.34Å; T334-L338 WeakPolarHBondContact O-CB 3.22Å; T334-L338 WeakPolarHBondContact O-CG 3.19Å; T334-L338 PolarHBondContact O-N 3.44Å
335	F	94.8	Very high	92.3	Very high	103 Å²	103	40.6 Å²	40.6	45%	0.452	23%	0.232	S	C	.	.	H	α-helix	trans	-61.9	-43.7	178.1	-72.5	-57.5	0	0	0	111.8	L331 S337 L338 I339 F396	L331-F335 HydrophobicContact CB-CD2 4.4Å; L331-F335 HydrophobicContact CB-CE2 4.27Å; L331-F335 HydrophobicContact CD2-CE2 4.47Å; L331-F335 WeakPolarHBondContact O-CD2 3.48Å; L331-F335 PolarHBondContact O-N 2.92Å; F335-S337 VanDerWaalsContact C-N 3.32Å; F335-S337 PolarHBondContact O-N 3Å; F335-L338 PolarHBondContact O-N 3.27Å; F335-I339 HydrophobicContact CB-CD1 4.49Å; F335-I339 VanDerWaalsContact O-CB 3.31Å; F335-I339 WeakPolarHBondContact O-CB 3.39Å; F335-I339 VanDerWaalsContact O-CG1 3.23Å; F335-I339 WeakPolarHBondContact O-CG1 3.45Å; F335-I339 PolarHBondContact O-N 3.32Å; F335-F396 HydrophobicContact CB-CE2 4.02Å; F335-F396 HydrophobicContact CB-CZ 4.23Å
336	Y	94.7	Very high	92.5	Very high	3 Å²	3	43.4 Å²	43.4	1%	0.012	25%	0.25	C	C	.	.	H	α-helix	trans	-53.2	-49.8	173.7	178.3	-88.1	0	0	0	111.7	L198 S315 L318 L319 L322 N332 T334 R340 F396 A399	L198-Y336 HydrophobicContact CD1-CE1 4.03Å; S315-Y336 PolarHBondContact O-OH 3.38Å; L318-Y336 HydrophobicContact CB-CE2 4.26Å; L319-Y336 HydrophobicContact CD1-CD1 4.45Å; L319-Y336 HydrophobicContact CD1-CE1 3.86Å; L319-Y336 PolarHBondContact N-OH 3.42Å; L322-Y336 HydrophobicContact CD1-CD1 3.95Å; L322-Y336 HydrophobicContact CD1-CD2 3.92Å; L322-Y336 HydrophobicContact CD1-CE1 4.42Å; L322-Y336 HydrophobicContact CD1-CE2 4.33Å; L322-Y336 HydrophobicContact CD1-CG 3.68Å; L322-Y336 HydrophobicContact CD2-CD2 3.74Å; L322-Y336 HydrophobicContact CD2-CE2 4.4Å; L322-Y336 HydrophobicContact CD2-CG 4.1Å; L322-Y336 HydrophobicContact CG-CD2 4.18Å; L322-Y336 HydrophobicContact CG-CG 4.4Å; N332-Y336 WeakPolarHBondContact O-CB 3.36Å; N332-Y336 PolarHBondContact O-N 3.06Å; T334-Y336 PolarHBondContact O-N 3.47Å; Y336-R340 HydrophobicContact CE1-CG 4.41Å; Y336-R340 VanDerWaalsContact O-CB 3.28Å; Y336-R340 WeakPolarHBondContact O-CB 3.43Å; Y336-R340 WeakPolarHBondContact O-CG 3.31Å; Y336-R340 PolarHBondContact O-N 3.3Å; Y336-R340 VanDerWaalsContact O-N 3.09Å; Y336-R340 PolarHBondContact OH-NH1 3.1Å; Y336-F396 HydrophobicContact CD2-CD1 4.32Å; Y336-F396 HydrophobicContact CD2-CE1 4.43Å; Y336-A399 HydrophobicContact CD2-CB 3.65Å; Y336-A399 HydrophobicContact CE2-CB 3.25Å
337	S	94.4	Very high	92.7	Very high	3 Å²	3	41.3 Å²	41.3	2%	0.021	24%	0.236	C	C	.	.	H	α-helix	trans	-67.9	-43	-177.9	-56.4	0	0	0	0	112.3	L198 S333 T334 F335 W341	L198-S337 WeakPolarHBondContact CB-OG 3.38Å; S333-S337 WeakPolarHBondContact O-CB 3.24Å; S333-S337 PolarHBondContact O-N 3.33Å; S333-S337 PolarHBondContact O-OG 2.9Å; T334-S337 PolarHBondContact O-N 3.14Å; F335-S337 VanDerWaalsContact C-N 3.32Å; F335-S337 PolarHBondContact O-N 3Å; S337-W341 WeakPolarHBondContact O-CB 3.42Å; S337-W341 PolarHBondContact O-N 3.31Å
338	L	95.2	Very high	92.7	Very high	71 Å²	71	38.3 Å²	38.3	37%	0.372	21%	0.205	S	C	.	.	H	α-helix	trans	-66.7	-45.1	-179.9	-73.5	175	0	0	0	112.5	L199 T334 F335 W341 S342	L199-L338 HydrophobicContact CD1-CD2 4.29Å; L199-L338 HydrophobicContact CD1-CG 4.25Å; L199-L338 HydrophobicContact CD2-CD2 3.82Å; T334-L338 HydrophobicContact CG2-CD1 3.78Å; T334-L338 HydrophobicContact CG2-CG 4.34Å; T334-L338 WeakPolarHBondContact O-CB 3.22Å; T334-L338 WeakPolarHBondContact O-CG 3.19Å; T334-L338 PolarHBondContact O-N 3.44Å; F335-L338 PolarHBondContact O-N 3.27Å; L338-W341 PolarHBondContact O-N 2.91Å; L338-S342 WeakPolarHBondContact O-CB 3.34Å; L338-S342 PolarHBondContact O-N 3.23Å; L338-S342 PolarHBondContact O-OG 3.48Å
339	I	95.4	Very high	92.6	Very high	56 Å²	56	38 Å²	38	29%	0.287	20%	0.203	S	C	.	.	H	α-helix	trans	-63.9	-44.6	178	-68.5	169.2	0	0	0	110	F335 W341 S342 V343 F396 A400	F335-I339 HydrophobicContact CB-CD1 4.49Å; F335-I339 VanDerWaalsContact O-CB 3.31Å; F335-I339 WeakPolarHBondContact O-CB 3.39Å; F335-I339 VanDerWaalsContact O-CG1 3.23Å; F335-I339 WeakPolarHBondContact O-CG1 3.45Å; F335-I339 PolarHBondContact O-N 3.32Å; I339-W341 VanDerWaalsContact C-N 3.3Å; I339-W341 PolarHBondContact O-N 3Å; I339-S342 PolarHBondContact O-N 3.44Å; I339-S342 PolarHBondContact O-OG 3.11Å; I339-S342 VanDerWaalsContact O-OG 3.05Å; I339-V343 HydrophobicContact CG2-CG2 4.38Å; I339-V343 WeakPolarHBondContact O-CB 3.1Å; I339-V343 WeakPolarHBondContact O-CG2 3.25Å; I339-V343 PolarHBondContact O-N 3.15Å; I339-F396 HydrophobicContact CD1-CB 4.42Å; I339-F396 HydrophobicContact CD1-CD2 4.18Å; I339-F396 HydrophobicContact CD1-CG 4.48Å; I339-A400 HydrophobicContact CG2-CB 3.5Å
340	R	93.7	Very high	92.4	Very high	6 Å²	6	40.1 Å²	40.1	2%	0.023	21%	0.213	C	C	.	.	H	α-helix	trans	-58.8	-42.8	175.4	-80.6	-176.1	69.4	113.4	26.1	112.3	N195 Y336 A344 A399 T402 S403	N195-R340 PolarHBondContact OD1-NE 3.3Å; Y336-R340 HydrophobicContact CE1-CG 4.41Å; Y336-R340 VanDerWaalsContact O-CB 3.28Å; Y336-R340 WeakPolarHBondContact O-CB 3.43Å; Y336-R340 WeakPolarHBondContact O-CG 3.31Å; Y336-R340 PolarHBondContact O-N 3.3Å; Y336-R340 VanDerWaalsContact O-N 3.09Å; Y336-R340 PolarHBondContact OH-NH1 3.1Å; R340-A344 VanDerWaalsContact O-CB 3.28Å; R340-A344 WeakPolarHBondContact O-CB 3.49Å; R340-A344 PolarHBondContact O-N 3.32Å; R340-A344 VanDerWaalsContact O-N 3.17Å; R340-A399 HydrophobicContact CG-CB 4.26Å; R340-T402 PolarHBondContact NH1-OG1 2.8Å; R340-T402 VanDerWaalsContact NH1-OG1 3.15Å; R340-T402 PolarHBondContact NH2-OG1 3.49Å; R340-S403 WeakPolarHBondContact CB-OG 3.34Å; R340-S403 PolarHBondContact NE-OG 3.5Å; R340-S403 VanDerWaalsContact NE-OG 3.14Å; R340-S403 PolarHBondContact NH2-OG 2.91Å; R340-S403 WeakPolarHBondContact O-CB 3.31Å; R340-S403 PolarHBondContact O-OG 3.13Å
341	W	92.9	Very high	91.9	Very high	88 Å²	88	40.3 Å²	40.3	33%	0.333	22%	0.215	S	C	.	.	H	α-helix	trans	-68	-49.3	178.4	177.6	72.9	0	0	0	111.8	I191 N195 I196 S337 L338 I339 V343 A344 V345	I191-W341 PolarHBondContact O-NE1 3.24Å; N195-W341 HydrophobicContact CB-CB 4Å; I196-W341 HydrophobicContact CD1-CZ2 4.47Å; I196-W341 VanDerWaalsContact CG1-CD1 3.47Å; I196-W341 HydrophobicContact CG1-CG 4.22Å; S337-W341 WeakPolarHBondContact O-CB 3.42Å; S337-W341 PolarHBondContact O-N 3.31Å; L338-W341 PolarHBondContact O-N 2.91Å; I339-W341 VanDerWaalsContact C-N 3.3Å; I339-W341 PolarHBondContact O-N 3Å; W341-V343 PolarHBondContact O-N 3.28Å; W341-A344 WeakPolarHBondContact O-CB 3.39Å; W341-A344 PolarHBondContact O-N 3.4Å; W341-V345 HydrophobicContact CD2-CG2 4.35Å; W341-V345 HydrophobicContact CZ2-CG2 4.21Å; W341-V345 WeakPolarHBondContact O-CG2 3.41Å; W341-V345 PolarHBondContact O-N 3.29Å
342	S	93.4	Very high	91.3	Very high	50 Å²	50	41.6 Å²	41.6	35%	0.35	21%	0.213	S	C	.	.	H	α-helix	trans	-61.5	-44.4	-177.9	65.5	0	0	0	0	111.8	L338 I339 A344 V345 T346	L338-S342 WeakPolarHBondContact O-CB 3.34Å; L338-S342 PolarHBondContact O-N 3.23Å; L338-S342 PolarHBondContact O-OG 3.48Å; I339-S342 PolarHBondContact O-N 3.44Å; I339-S342 PolarHBondContact O-OG 3.11Å; I339-S342 VanDerWaalsContact O-OG 3.05Å; S342-A344 PolarHBondContact O-N 2.88Å; S342-V345 PolarHBondContact O-N 3.45Å; S342-T346 WeakPolarHBondContact O-CB 3.26Å; S342-T346 PolarHBondContact O-N 3.18Å; S342-T346 PolarHBondContact O-OG1 3.08Å; S342-T346 VanDerWaalsContact O-OG1 3.09Å
343	V	93.5	Very high	90.9	Very high	50 Å²	50	47.9 Å²	47.9	30%	0.303	24%	0.24	S	C	.	.	H	α-helix	trans	-67.9	-36.2	178.3	175.9	0	0	0	0	111.6	I339 W341 A347 A400 P404	I339-V343 HydrophobicContact CG2-CG2 4.38Å; I339-V343 WeakPolarHBondContact O-CB 3.1Å; I339-V343 WeakPolarHBondContact O-CG2 3.25Å; I339-V343 PolarHBondContact O-N 3.15Å; W341-V343 PolarHBondContact O-N 3.28Å; V343-A347 VanDerWaalsContact O-CB 3.25Å; V343-A347 WeakPolarHBondContact O-CB 3.46Å; V343-A347 PolarHBondContact O-N 3.36Å; V343-A400 HydrophobicContact CB-CB 4.47Å; V343-A400 WeakPolarHBondContact CG1-O 3.48Å; V343-A400 HydrophobicContact CG2-CB 4.12Å; V343-P404 HydrophobicContact CG1-CG 3.63Å
344	A	90.8	Very high	90.4	Very high	0 Å²	0	50.3 Å²	50.3	0%	0	26%	0.255	C	S	.	.	H	α-helix	trans	-63.4	-44.1	173.9	0	0	0	0	0	112.5	R340 W341 S342 S348	R340-A344 VanDerWaalsContact O-CB 3.28Å; R340-A344 WeakPolarHBondContact O-CB 3.49Å; R340-A344 PolarHBondContact O-N 3.32Å; R340-A344 VanDerWaalsContact O-N 3.17Å; W341-A344 WeakPolarHBondContact O-CB 3.39Å; W341-A344 PolarHBondContact O-N 3.4Å; S342-A344 PolarHBondContact O-N 2.88Å; A344-S348 WeakPolarHBondContact O-CB 3.48Å; A344-S348 PolarHBondContact O-N 3.38Å; A344-S348 VanDerWaalsContact O-N 3.09Å; A344-S348 PolarHBondContact O-OG 3.03Å
345	V	90.6	Very high	89.5	Confident	23 Å²	23	53.7 Å²	53.7	14%	0.139	28%	0.28	C	S	.	.	H	α-helix	trans	-64.6	-50.2	177.2	173	0	0	0	0	110.1	S190 W341 S342 A347 S348 L349	S190-V345 WeakPolarHBondContact O-CG2 3.39Å; W341-V345 HydrophobicContact CD2-CG2 4.35Å; W341-V345 HydrophobicContact CZ2-CG2 4.21Å; W341-V345 WeakPolarHBondContact O-CG2 3.41Å; W341-V345 PolarHBondContact O-N 3.29Å; S342-V345 PolarHBondContact O-N 3.45Å; V345-A347 PolarHBondContact O-N 2.83Å; V345-S348 PolarHBondContact O-N 3.01Å; V345-S348 VanDerWaalsContact O-N 3.13Å; V345-L349 HydrophobicContact CG1-CD1 4.01Å; V345-L349 HydrophobicContact CG1-CG 4.37Å; V345-L349 WeakPolarHBondContact O-CG 3.49Å; V345-L349 PolarHBondContact O-N 2.91Å
346	T	91.1	Very high	88.6	Confident	77 Å²	77	53.8 Å²	53.8	47%	0.472	29%	0.294	S	S	.	.	H	α-helix	trans	-60.3	-45.3	179.6	-61.9	0	0	0	0	111.9	S342 S348 L349 I350	S342-T346 WeakPolarHBondContact O-CB 3.26Å; S342-T346 PolarHBondContact O-N 3.18Å; S342-T346 PolarHBondContact O-OG1 3.08Å; S342-T346 VanDerWaalsContact O-OG1 3.09Å; T346-S348 VanDerWaalsContact C-N 3.27Å; T346-S348 PolarHBondContact O-N 2.9Å; T346-L349 PolarHBondContact O-N 2.91Å; T346-I350 HydrophobicContact CG2-CD1 3.96Å; T346-I350 HydrophobicContact CG2-CG1 4.5Å; T346-I350 VanDerWaalsContact O-CG1 3.29Å; T346-I350 WeakPolarHBondContact O-CG1 3.5Å; T346-I350 PolarHBondContact O-N 2.9Å
347	A	88.9	Confident	88	Confident	16 Å²	16	56.3 Å²	56.3	13%	0.132	31%	0.306	C	S	.	.	H	α-helix	trans	-61.6	-35.9	176.7	0	0	0	0	0	112.5	V343 V345 I350 D351 P404	V343-A347 VanDerWaalsContact O-CB 3.25Å; V343-A347 WeakPolarHBondContact O-CB 3.46Å; V343-A347 PolarHBondContact O-N 3.36Å; V345-A347 PolarHBondContact O-N 2.83Å; A347-I350 PolarHBondContact O-N 2.98Å; A347-D351 PolarHBondContact O-N 3.19Å; A347-P404 HydrophobicContact CB-CB 3.63Å; A347-P404 HydrophobicContact CB-CG 3.72Å
348	S	86.1	Confident	87.5	Confident	7 Å²	7	56.7 Å²	56.7	5%	0.049	31%	0.311	C	S	.	.	H	α-helix	trans	-75.3	-30.7	178.7	-56.7	0	0	0	0	112.8	S190 A344 V345 T346 R352	S190-S348 WeakPolarHBondContact OG-CB 3.4Å; S190-S348 PolarHBondContact OG-OG 3.46Å; A344-S348 WeakPolarHBondContact O-CB 3.48Å; A344-S348 PolarHBondContact O-N 3.38Å; A344-S348 VanDerWaalsContact O-N 3.09Å; A344-S348 PolarHBondContact O-OG 3.03Å; V345-S348 PolarHBondContact O-N 3.01Å; V345-S348 VanDerWaalsContact O-N 3.13Å; T346-S348 VanDerWaalsContact C-N 3.27Å; T346-S348 PolarHBondContact O-N 2.9Å; S348-R352 WeakPolarHBondContact O-CB 3.34Å; S348-R352 PolarHBondContact O-N 3.44Å; S348-R352 VanDerWaalsContact O-N 3.14Å
349	L	87.5	Confident	87.1	Confident	62 Å²	62	54.6 Å²	54.6	33%	0.325	30%	0.298	S	S	.	.	H	α-helix	trans	-68	-42.6	168.9	-66.8	171.9	0	0	0	110.7	L187 V345 T346 R352 F353	L187-L349 HydrophobicContact CD1-CD2 3.82Å; V345-L349 HydrophobicContact CG1-CD1 4.01Å; V345-L349 HydrophobicContact CG1-CG 4.37Å; V345-L349 WeakPolarHBondContact O-CG 3.49Å; V345-L349 PolarHBondContact O-N 2.91Å; T346-L349 PolarHBondContact O-N 2.91Å; L349-R352 WeakPolarHBondContact O-CB 3.43Å; L349-R352 PolarHBondContact O-N 3.03Å; L349-R352 VanDerWaalsContact O-N 3.16Å; L349-F353 HydrophobicContact CB-CD2 4.32Å; L349-F353 HydrophobicContact CB-CE2 4.45Å; L349-F353 HydrophobicContact CD2-CE2 3.98Å; L349-F353 WeakPolarHBondContact O-CD2 3.31Å; L349-F353 PolarHBondContact O-N 3.02Å
350	I	87	Confident	86.9	Confident	59 Å²	59	54.5 Å²	54.5	30%	0.303	30%	0.295	S	S	.	.	H	α-helix	trans	-61.4	-47.1	175.1	-67.2	166.1	0	0	0	110.5	T346 A347 R352 F353 V354 M357	T346-I350 HydrophobicContact CG2-CD1 3.96Å; T346-I350 HydrophobicContact CG2-CG1 4.5Å; T346-I350 VanDerWaalsContact O-CG1 3.29Å; T346-I350 WeakPolarHBondContact O-CG1 3.5Å; T346-I350 PolarHBondContact O-N 2.9Å; A347-I350 PolarHBondContact O-N 2.98Å; I350-R352 PolarHBondContact O-N 3.38Å; I350-F353 PolarHBondContact O-N 3.23Å; I350-V354 HydrophobicContact CG2-CB 4.14Å; I350-V354 HydrophobicContact CG2-CG2 3.98Å; I350-V354 WeakPolarHBondContact O-CA 3.45Å; I350-V354 VanDerWaalsContact O-CB 3.26Å; I350-V354 WeakPolarHBondContact O-CB 3.29Å; I350-V354 PolarHBondContact O-N 2.93Å; I350-M357 HydrophobicContact CG2-CB 4.43Å; I350-M357 HydrophobicContact CG2-CE 3.88Å; I350-M357 HydrophobicContact CG2-CG 4.47Å; I350-M357 HydrophobicContact CG2-SD 3.4Å; I350-M357 WeakPolarHBondContact CG2-SD 3.45Å
351	D	82.9	Confident	86.8	Confident	17 Å²	17	59.2 Å²	59.2	9%	0.091	32%	0.318	C	S	.	.	H	α-helix	trans	-57	-36.5	175.7	-175.7	59	0	0	0	111.7	L186 A347 R359 I362 K477	L186-D351 HydrophobicContact CD2-CB 4.29Å; L186-D351 VanDerWaalsContact CD2-OD2 3.3Å; L186-D351 WeakPolarHBondContact CD2-OD2 3.36Å; A347-D351 PolarHBondContact O-N 3.19Å; D351-R359 IonicContact OD2-NE 3.81Å; D351-I362 HydrophobicContact CB-CD1 4.11Å; D351-K477 WeakPolarHBondContact O-CE 3.49Å; D351-K477 PolarHBondContact O-NZ 3.47Å; D351-K477 WeakPolarHBondContact OD1-CE 3.05Å; D351-K477 IonicContact OD1-NZ 2.79Å; D351-K477 PolarHBondContact OD1-NZ 2.97Å
352	R	81.8	Confident	86.7	Confident	123 Å²	123	55.6 Å²	55.6	46%	0.464	30%	0.304	S	S	.	.	H	α-helix	trans	-72.6	-47.2	178.8	178.9	175	179.5	139.3	1.2	113.6	S348 L349 I350	S348-R352 WeakPolarHBondContact O-CB 3.34Å; S348-R352 PolarHBondContact O-N 3.44Å; S348-R352 VanDerWaalsContact O-N 3.14Å; L349-R352 WeakPolarHBondContact O-CB 3.43Å; L349-R352 PolarHBondContact O-N 3.03Å; L349-R352 VanDerWaalsContact O-N 3.16Å; I350-R352 PolarHBondContact O-N 3.38Å
353	F	84	Confident	86.8	Confident	148 Å²	148	53.2 Å²	53.2	65%	0.649	29%	0.288	S	S	*	.	H	α-helix	trans	-91.5	-25.5	-170.6	-68.5	-65.4	0	0	0	113.3	L349 I350	L349-F353 HydrophobicContact CB-CD2 4.32Å; L349-F353 HydrophobicContact CB-CE2 4.45Å; L349-F353 HydrophobicContact CD2-CE2 3.98Å; L349-F353 WeakPolarHBondContact O-CD2 3.31Å; L349-F353 PolarHBondContact O-N 3.02Å; I350-F353 PolarHBondContact O-N 3.23Å
354	V	84.2	Confident	86.9	Confident	52 Å²	52	52.5 Å²	52.5	32%	0.315	28%	0.284	S	S	.	.			trans	-103.7	96.5	-177.5	-172.7	0	0	0	0	109.1	I350 S356 M357 K477	I350-V354 HydrophobicContact CG2-CB 4.14Å; I350-V354 HydrophobicContact CG2-CG2 3.98Å; I350-V354 WeakPolarHBondContact O-CA 3.45Å; I350-V354 VanDerWaalsContact O-CB 3.26Å; I350-V354 WeakPolarHBondContact O-CB 3.29Å; I350-V354 PolarHBondContact O-N 2.93Å; V354-S356 VanDerWaalsContact C-N 3.25Å; V354-S356 VanDerWaalsContact CG1-OG 3.26Å; V354-S356 WeakPolarHBondContact CG1-OG 3.37Å; V354-S356 PolarHBondContact O-N 3.37Å; V354-M357 HydrophobicContact CB-CB 4.22Å; V354-M357 HydrophobicContact CG1-CB 3.88Å; V354-M357 PolarHBondContact O-N 2.91Å; V354-K477 PolarHBondContact O-NZ 3.06Å
355	S	76	Confident	87.2	Confident	113 Å²	113	55.6 Å²	55.6	79%	0.79	30%	0.302	S	S	*	.	T	Hydrogen-bonded Turn	trans	-63.7	-30.5	179.2	57.4	0	0	0	0	112.9	M357	S355-M357 VanDerWaalsContact C-N 3.32Å; S355-M357 PolarHBondContact O-N 3.47Å
356	S	77.5	Confident	87.5	Confident	106 Å²	106	55.6 Å²	55.6	74%	0.741	30%	0.304	S	S	*	.	T	Hydrogen-bonded Turn	trans	-71.2	-24.3	179	61.4	0	0	0	0	113.6	V354 G358	V354-S356 VanDerWaalsContact C-N 3.25Å; V354-S356 VanDerWaalsContact CG1-OG 3.26Å; V354-S356 WeakPolarHBondContact CG1-OG 3.37Å; V354-S356 PolarHBondContact O-N 3.37Å; S356-G358 PolarHBondContact O-N 3.42Å; S356-G358 VanDerWaalsContact O-N 3.17Å
357	M	80.8	Confident	87.8	Confident	56 Å²	56	52.1 Å²	52.1	28%	0.276	28%	0.282	S	S	.	.			trans	-83.6	99.5	-178.5	-168.4	167.8	-63.3	0	0	109.8	I350 V354 S355 I362 K477	I350-M357 HydrophobicContact CG2-CB 4.43Å; I350-M357 HydrophobicContact CG2-CE 3.88Å; I350-M357 HydrophobicContact CG2-CG 4.47Å; I350-M357 HydrophobicContact CG2-SD 3.4Å; I350-M357 WeakPolarHBondContact CG2-SD 3.45Å; V354-M357 HydrophobicContact CB-CB 4.22Å; V354-M357 HydrophobicContact CG1-CB 3.88Å; V354-M357 PolarHBondContact O-N 2.91Å; S355-M357 VanDerWaalsContact C-N 3.32Å; S355-M357 PolarHBondContact O-N 3.47Å; M357-I362 HydrophobicContact CG-CD1 4.2Å; M357-I362 HydrophobicContact CG-CG1 3.85Å; M357-I362 HydrophobicContact SD-CD1 4.15Å; M357-I362 HydrophobicContact SD-CG1 3.73Å; M357-K477 WeakPolarHBondContact O-CD 3.44Å; M357-K477 WeakPolarHBondContact O-CE 3.24Å; M357-K477 PolarHBondContact O-NZ 3.29Å
358	G	83.4	Confident	88.2	Confident	11 Å²	11	56.9 Å²	56.9	11%	0.113	30%	0.3	C	S	.	.			trans	-65.4	156.5	173.6	0	0	0	0	0	113.2	S356 K360 H361 I362 E475	S356-G358 PolarHBondContact O-N 3.42Å; S356-G358 VanDerWaalsContact O-N 3.17Å; G358-K360 VanDerWaalsContact C-N 3.32Å; G358-H361 WeakPolarHBondContact O-CB 3.23Å; G358-H361 PolarHBondContact O-N 2.88Å; G358-I362 PolarHBondContact O-N 2.92Å; G358-E475 VanDerWaalsContact CA-CD 3.48Å; G358-E475 WeakPolarHBondContact CA-OE2 3.35Å
359	R	86.8	Confident	88.8	Confident	26 Å²	26	59 Å²	59	10%	0.098	31%	0.312	C	S	.	.	H	α-helix	trans	-70.4	-32.4	177.7	-70	-180	-169.5	166.4	14.4	112.1	D351 H361 I362 I363 V412 E415 E475 K477	D351-R359 IonicContact OD2-NE 3.81Å; R359-H361 VanDerWaalsContact C-N 3.26Å; R359-H361 PolarHBondContact O-N 3.25Å; R359-I362 PolarHBondContact O-N 2.75Å; R359-I363 WeakPolarHBondContact O-CG1 3.47Å; R359-I363 PolarHBondContact O-N 3.34Å; R359-V412 HydrophobicContact CB-CG2 4.24Å; R359-E415 IonicContact CZ-OE1 3.47Å; R359-E415 IonicContact CZ-OE2 2.84Å; R359-E415 IonicContact NH1-OE1 2.65Å; R359-E415 PolarHBondContact NH1-OE1 3.25Å; R359-E415 IonicContact NH1-OE2 3.68Å; R359-E415 PolarHBondContact NH1-OE2 3.01Å; R359-E415 IonicContact NH2-OE1 3.71Å; R359-E415 PolarHBondContact NH2-OE1 3.25Å; R359-E415 IonicContact NH2-OE2 2.7Å; R359-E475 VanDerWaalsContact N-CD 3.33Å; R359-E475 PolarHBondContact N-OE1 2.92Å; R359-E475 PolarHBondContact N-OE2 3.21Å; R359-E475 VanDerWaalsContact N-OE2 3.1Å; R359-K477 HydrophobicContact CG-CB 4.21Å
360	K	91.3	Very high	89.3	Confident	54 Å²	54	56.2 Å²	56.2	24%	0.235	30%	0.298	C	S	.	.	H	α-helix	trans	-60.4	-41.9	172.5	-178.9	175.6	179.8	165	0	110.2	G358 I363 V364 F469 T470 I473 E475	G358-K360 VanDerWaalsContact C-N 3.32Å; K360-I363 PolarHBondContact O-N 2.94Å; K360-V364 HydrophobicContact CG-CG2 4.02Å; K360-V364 VanDerWaalsContact O-CB 3.29Å; K360-V364 WeakPolarHBondContact O-CB 3.36Å; K360-V364 WeakPolarHBondContact O-CG2 3.44Å; K360-V364 PolarHBondContact O-N 3.38Å; K360-F469 HydrophobicContact CB-CE1 4.42Å; K360-F469 HydrophobicContact CG-CD1 4.48Å; K360-F469 HydrophobicContact CG-CE1 4.07Å; K360-T470 WeakPolarHBondContact CE-O 3.26Å; K360-T470 PolarHBondContact NZ-O 3.39Å; K360-I473 WeakPolarHBondContact CD-O 3.42Å; K360-I473 WeakPolarHBondContact CE-O 3.45Å; K360-I473 PolarHBondContact NZ-O 3.13Å; K360-E475 WeakPolarHBondContact CA-OE2 3.17Å; K360-E475 HydrophobicContact CB-CB 4.42Å; K360-E475 WeakPolarHBondContact CB-OE2 3.14Å; K360-E475 PolarHBondContact N-OE2 3.33Å
361	H	91.8	Very high	89.8	Confident	106 Å²	106	54.4 Å²	54.4	49%	0.491	29%	0.289	S	S	.	.	H	α-helix	trans	-61	-47.8	178.4	-174.7	-87.1	0	0	0	111.7	G358 R359 I363 V364 T365	G358-H361 WeakPolarHBondContact O-CB 3.23Å; G358-H361 PolarHBondContact O-N 2.88Å; R359-H361 VanDerWaalsContact C-N 3.26Å; R359-H361 PolarHBondContact O-N 3.25Å; H361-I363 PolarHBondContact O-N 3.46Å; H361-V364 PolarHBondContact O-N 2.8Å; H361-T365 WeakPolarHBondContact O-CB 3.33Å; H361-T365 PolarHBondContact O-N 2.83Å; H361-T365 PolarHBondContact O-OG1 3.24Å
362	I	92.2	Very high	90.6	Very high	11 Å²	11	57 Å²	57	6%	0.056	31%	0.305	C	S	.	.	H	α-helix	trans	-57.9	-49.9	176.8	-63.8	172.9	0	0	0	110.8	D351 M357 G358 R359 V364 C366 P404	D351-I362 HydrophobicContact CB-CD1 4.11Å; M357-I362 HydrophobicContact CG-CD1 4.2Å; M357-I362 HydrophobicContact CG-CG1 3.85Å; M357-I362 HydrophobicContact SD-CD1 4.15Å; M357-I362 HydrophobicContact SD-CG1 3.73Å; G358-I362 PolarHBondContact O-N 2.92Å; R359-I362 PolarHBondContact O-N 2.75Å; I362-V364 PolarHBondContact O-N 3.26Å; I362-C366 VanDerWaalsContact O-CB 3.31Å; I362-C366 WeakPolarHBondContact O-CB 3.5Å; I362-C366 PolarHBondContact O-N 2.96Å; I362-C366 PolarHBondContact O-SG 3.39Å; I362-C366 VanDerWaalsContact O-SG 3.36Å; I362-P404 HydrophobicContact CG2-CB 4.14Å
363	I	94.6	Very high	91.3	Very high	0 Å²	0	51.4 Å²	51.4	0%	0	29%	0.285	C	S	.	.	H	α-helix	trans	-62	-47.3	-178.2	-68.4	165.8	0	0	0	111	R359 K360 H361 T367 I405 I409 V412 F465 F469	R359-I363 WeakPolarHBondContact O-CG1 3.47Å; R359-I363 PolarHBondContact O-N 3.34Å; K360-I363 PolarHBondContact O-N 2.94Å; H361-I363 PolarHBondContact O-N 3.46Å; I363-T367 WeakPolarHBondContact O-CB 3.3Å; I363-T367 PolarHBondContact O-N 3.46Å; I363-T367 PolarHBondContact O-OG1 2.82Å; I363-I405 HydrophobicContact CG2-CG2 4.38Å; I363-I409 HydrophobicContact CD1-CG1 3.8Å; I363-I409 HydrophobicContact CG1-CG1 4.25Å; I363-I409 HydrophobicContact CG2-CG1 4.46Å; I363-V412 HydrophobicContact CD1-CG2 3.91Å; I363-F465 HydrophobicContact CG2-CE2 3.63Å; I363-F465 HydrophobicContact CG2-CZ 3.73Å; I363-F469 HydrophobicContact CB-CD1 4.49Å; I363-F469 HydrophobicContact CB-CE1 3.94Å; I363-F469 HydrophobicContact CB-CZ 4.2Å; I363-F469 HydrophobicContact CD1-CE1 3.97Å; I363-F469 HydrophobicContact CD1-CE2 4.15Å; I363-F469 HydrophobicContact CD1-CZ 3.42Å; I363-F469 VanDerWaalsContact CD1-CZ 3.42Å; I363-F469 HydrophobicContact CG1-CZ 4.4Å; I363-F469 HydrophobicContact CG2-CD1 3.83Å; I363-F469 HydrophobicContact CG2-CD2 4.32Å; I363-F469 HydrophobicContact CG2-CE1 3.65Å; I363-F469 HydrophobicContact CG2-CE2 4.16Å; I363-F469 HydrophobicContact CG2-CG 4.17Å; I363-F469 HydrophobicContact CG2-CZ 3.84Å
364	V	96.4	Very high	92	Very high	36 Å²	36	44.4 Å²	44.4	22%	0.218	25%	0.254	C	S	.	.	H	α-helix	trans	-64.5	-48.2	-178	169.6	0	0	0	0	111	K360 H361 I362 T367 F368 L466 F469 T470	K360-V364 HydrophobicContact CG-CG2 4.02Å; K360-V364 VanDerWaalsContact O-CB 3.29Å; K360-V364 WeakPolarHBondContact O-CB 3.36Å; K360-V364 WeakPolarHBondContact O-CG2 3.44Å; K360-V364 PolarHBondContact O-N 3.38Å; H361-V364 PolarHBondContact O-N 2.8Å; I362-V364 PolarHBondContact O-N 3.26Å; V364-T367 PolarHBondContact O-N 2.78Å; V364-F368 WeakPolarHBondContact O-CB 3.35Å; V364-F368 PolarHBondContact O-N 3.39Å; V364-L466 HydrophobicContact CB-CD1 4.43Å; V364-L466 HydrophobicContact CG1-CD1 3.91Å; V364-F469 HydrophobicContact CG2-CD1 4.18Å; V364-T470 HydrophobicContact CB-CG2 4.32Å; V364-T470 HydrophobicContact CG1-CG2 3.77Å; V364-T470 HydrophobicContact CG2-CG2 3.52Å
365	T	95.7	Very high	92.6	Very high	64 Å²	64	45.4 Å²	45.4	39%	0.393	26%	0.257	S	S	.	.	H	α-helix	trans	-64.3	-46.2	-179.5	-59	0	0	0	0	111.6	H361 T367 F368 V369	H361-T365 WeakPolarHBondContact O-CB 3.33Å; H361-T365 PolarHBondContact O-N 2.83Å; H361-T365 PolarHBondContact O-OG1 3.24Å; T365-T367 PolarHBondContact O-N 2.73Å; T365-F368 PolarHBondContact O-N 3.19Å; T365-V369 WeakPolarHBondContact O-CG2 3.15Å; T365-V369 PolarHBondContact O-N 3.42Å
366	C	96.7	Very high	93.6	Very high	24 Å²	24	41 Å²	41	16%	0.162	23%	0.23	C	C	.	.	H	α-helix	trans	-65.8	-38.8	176.8	-69.3	0	0	0	0	112	I362 F368 V369 V370 A401 I405	I362-C366 VanDerWaalsContact O-CB 3.31Å; I362-C366 WeakPolarHBondContact O-CB 3.5Å; I362-C366 PolarHBondContact O-N 2.96Å; I362-C366 PolarHBondContact O-SG 3.39Å; I362-C366 VanDerWaalsContact O-SG 3.36Å; C366-F368 VanDerWaalsContact C-N 3.32Å; C366-F368 PolarHBondContact O-N 3.21Å; C366-V369 PolarHBondContact O-N 3.12Å; C366-V370 WeakPolarHBondContact O-CG2 3.21Å; C366-V370 PolarHBondContact O-N 3.03Å; C366-A401 HydrophobicContact CB-CB 4.19Å; C366-I405 HydrophobicContact CB-CD1 3.7Å; C366-I405 HydrophobicContact CB-CG1 3.48Å; C366-I405 VanDerWaalsContact CB-CG1 3.48Å
367	T	97.6	Very high	94.5	Very high	3 Å²	3	36 Å²	36	2%	0.018	20%	0.195	C	C	.	.	H	α-helix	trans	-66.3	-36.7	177.4	-55.3	0	0	0	0	111.1	I363 V364 T365 V370 L371 F465 L466	I363-T367 WeakPolarHBondContact O-CB 3.3Å; I363-T367 PolarHBondContact O-N 3.46Å; I363-T367 PolarHBondContact O-OG1 2.82Å; V364-T367 PolarHBondContact O-N 2.78Å; T365-T367 PolarHBondContact O-N 2.73Å; T367-V370 WeakPolarHBondContact O-CB 3.35Å; T367-V370 PolarHBondContact O-N 3.12Å; T367-L371 WeakPolarHBondContact O-CB 3.29Å; T367-L371 PolarHBondContact O-N 3.17Å; T367-F465 HydrophobicContact CG2-CB 4.32Å; T367-F465 HydrophobicContact CG2-CD2 3.73Å; T367-F465 HydrophobicContact CG2-CE2 4.16Å; T367-F465 HydrophobicContact CG2-CG 3.97Å; T367-L466 HydrophobicContact CG2-CB 3.93Å; T367-L466 HydrophobicContact CG2-CD1 4.21Å
368	F	98.1	Very high	95.2	Very high	117 Å²	117	34 Å²	34	51%	0.513	19%	0.185	S	C	.	.	H	α-helix	trans	-62.3	-44.3	173	180	-101.4	0	0	0	111.9	V364 T365 C366 V370 L371 V372 L466	V364-F368 WeakPolarHBondContact O-CB 3.35Å; V364-F368 PolarHBondContact O-N 3.39Å; T365-F368 PolarHBondContact O-N 3.19Å; C366-F368 VanDerWaalsContact C-N 3.32Å; C366-F368 PolarHBondContact O-N 3.21Å; F368-V370 VanDerWaalsContact C-N 3.34Å; F368-V370 PolarHBondContact O-N 2.97Å; F368-L371 WeakPolarHBondContact O-CB 3.46Å; F368-L371 PolarHBondContact O-N 2.87Å; F368-V372 HydrophobicContact CD1-CG2 4.27Å; F368-V372 HydrophobicContact CE1-CG2 3.82Å; F368-V372 HydrophobicContact CE2-CG2 4.19Å; F368-V372 HydrophobicContact CZ-CG2 3.78Å; F368-V372 WeakPolarHBondContact O-CG2 3.43Å; F368-V372 PolarHBondContact O-N 3.24Å; F368-L466 HydrophobicContact CB-CD2 4.33Å; F368-L466 HydrophobicContact CD2-CD2 4.09Å
369	V	98.2	Very high	95.8	Very high	51 Å²	51	36.9 Å²	36.9	31%	0.309	20%	0.201	S	C	.	.	H	α-helix	trans	-58.5	-46.2	173.6	172.3	0	0	0	0	111.1	T365 C366 L371 V372 C373 T397 A401	T365-V369 WeakPolarHBondContact O-CG2 3.15Å; T365-V369 PolarHBondContact O-N 3.42Å; C366-V369 PolarHBondContact O-N 3.12Å; V369-L371 VanDerWaalsContact C-N 3.33Å; V369-L371 PolarHBondContact O-N 3.4Å; V369-V372 PolarHBondContact O-N 3.07Å; V369-C373 PolarHBondContact O-N 2.86Å; V369-C373 PolarHBondContact O-SG 3.42Å; V369-T397 HydrophobicContact CG1-CG2 3.69Å; V369-A401 HydrophobicContact CB-CB 4.3Å; V369-A401 HydrophobicContact CG1-CB 4.09Å
370	V	98.2	Very high	96.2	Very high	3 Å²	3	36.3 Å²	36.3	2%	0.018	20%	0.2	C	C	.	.	H	α-helix	trans	-57.1	-46.4	175.7	171	0	0	0	0	111.1	I314 C366 T367 F368 C373 H374 A401 T402 I405	I314-V370 HydrophobicContact CD1-CG1 4.05Å; I314-V370 HydrophobicContact CG2-CG1 3.9Å; C366-V370 WeakPolarHBondContact O-CG2 3.21Å; C366-V370 PolarHBondContact O-N 3.03Å; T367-V370 WeakPolarHBondContact O-CB 3.35Å; T367-V370 PolarHBondContact O-N 3.12Å; F368-V370 VanDerWaalsContact C-N 3.34Å; F368-V370 PolarHBondContact O-N 2.97Å; V370-C373 PolarHBondContact O-N 3.3Å; V370-H374 PolarHBondContact O-N 3.26Å; V370-H374 PolarHBondContact O-ND1 3.15Å; V370-A401 HydrophobicContact CG2-CB 3.69Å; V370-T402 HydrophobicContact CG2-CG2 4.2Å; V370-I405 HydrophobicContact CG2-CD1 4.24Å
371	L	98.4	Very high	96.3	Very high	22 Å²	22	37 Å²	37	12%	0.115	20%	0.204	C	C	.	.	H	α-helix	trans	-59.9	-50	178.5	173.2	61.5	0	0	0	111.5	T367 F368 V369 C373 H374 I375 M459 S462 A463 L466	T367-L371 WeakPolarHBondContact O-CB 3.29Å; T367-L371 PolarHBondContact O-N 3.17Å; F368-L371 WeakPolarHBondContact O-CB 3.46Å; F368-L371 PolarHBondContact O-N 2.87Å; V369-L371 VanDerWaalsContact C-N 3.33Å; V369-L371 PolarHBondContact O-N 3.4Å; L371-C373 VanDerWaalsContact C-N 3.31Å; L371-C373 PolarHBondContact O-N 2.93Å; L371-H374 PolarHBondContact O-N 3.47Å; L371-H374 VanDerWaalsContact O-N 3.15Å; L371-I375 HydrophobicContact CD1-CD1 4.02Å; L371-I375 HydrophobicContact CD1-CG1 4.18Å; L371-I375 HydrophobicContact CG-CD1 3.95Å; L371-I375 WeakPolarHBondContact O-CG1 3.29Å; L371-I375 PolarHBondContact O-N 3.41Å; L371-M459 HydrophobicContact CD1-CG 3.98Å; L371-M459 WeakPolarHBondContact CD1-O 3.33Å; L371-S462 WeakPolarHBondContact CD1-OG 3.44Å; L371-A463 HydrophobicContact CD1-CB 3.99Å; L371-A463 HydrophobicContact CD2-CB 4.36Å; L371-L466 HydrophobicContact CD2-CD2 3.95Å
372	V	98.3	Very high	96.4	Very high	70 Å²	70	39.2 Å²	39.2	42%	0.424	21%	0.213	S	C	.	.	H	α-helix	trans	-59	-42.8	178.5	173.3	0	0	0	0	111.2	F368 V369 H374 I375 G376	F368-V372 HydrophobicContact CD1-CG2 4.27Å; F368-V372 HydrophobicContact CE1-CG2 3.82Å; F368-V372 HydrophobicContact CE2-CG2 4.19Å; F368-V372 HydrophobicContact CZ-CG2 3.78Å; F368-V372 WeakPolarHBondContact O-CG2 3.43Å; F368-V372 PolarHBondContact O-N 3.24Å; V369-V372 PolarHBondContact O-N 3.07Å; V372-H374 PolarHBondContact O-N 2.82Å; V372-I375 PolarHBondContact O-N 2.89Å; V372-G376 PolarHBondContact O-N 3.44Å
373	C	98	Very high	96.5	Very high	7 Å²	7	44.3 Å²	44.3	5%	0.047	24%	0.24	C	C	.	.	H	α-helix	trans	-62.9	-41.6	176.5	-68.1	0	0	0	0	112.5	V369 V370 L371 G376 L377 L394 A398	V369-C373 PolarHBondContact O-N 2.86Å; V369-C373 PolarHBondContact O-SG 3.42Å; V370-C373 PolarHBondContact O-N 3.3Å; L371-C373 VanDerWaalsContact C-N 3.31Å; L371-C373 PolarHBondContact O-N 2.93Å; C373-G376 PolarHBondContact O-N 3.24Å; C373-L377 WeakPolarHBondContact O-CG 3.44Å; C373-L377 PolarHBondContact O-N 3.02Å; C373-L394 HydrophobicContact CB-CD2 4.39Å; C373-A398 HydrophobicContact CB-CB 3.71Å
374	H	97.5	Very high	96.3	Very high	0 Å²	0	47 Å²	47	0%	0	27%	0.268	C	S	.	.	H	α-helix	trans	-69.9	-34.5	177.6	-75.4	80.8	0	0	0	112.7	V370 L371 V372 L377 T378 N458 M459	V370-H374 PolarHBondContact O-N 3.26Å; V370-H374 PolarHBondContact O-ND1 3.15Å; L371-H374 PolarHBondContact O-N 3.47Å; L371-H374 VanDerWaalsContact O-N 3.15Å; V372-H374 PolarHBondContact O-N 2.82Å; H374-L377 PolarHBondContact O-N 3.33Å; H374-T378 VanDerWaalsContact O-CB 3.28Å; H374-T378 WeakPolarHBondContact O-CB 3.35Å; H374-T378 PolarHBondContact O-N 3.32Å; H374-T378 PolarHBondContact O-OG1 3.19Å; H374-N458 WeakPolarHBondContact CD2-CB 3.46Å; H374-M459 HydrophobicContact CB-CB 3.98Å
375	I	97.8	Very high	96	Very high	73 Å²	73	48.1 Å²	48.1	37%	0.374	27%	0.274	S	S	.	.	H	α-helix	trans	-59.3	-50.9	169.7	-66.9	166.5	0	0	0	109.1	L371 V372 L377 T378 V379 M459	L371-I375 HydrophobicContact CD1-CD1 4.02Å; L371-I375 HydrophobicContact CD1-CG1 4.18Å; L371-I375 HydrophobicContact CG-CD1 3.95Å; L371-I375 WeakPolarHBondContact O-CG1 3.29Å; L371-I375 PolarHBondContact O-N 3.41Å; V372-I375 PolarHBondContact O-N 2.89Å; I375-L377 PolarHBondContact O-N 2.96Å; I375-T378 PolarHBondContact O-N 3.18Å; I375-V379 HydrophobicContact CG2-CG2 4.31Å; I375-V379 WeakPolarHBondContact O-CB 3.29Å; I375-V379 VanDerWaalsContact O-CG2 3.29Å; I375-V379 WeakPolarHBondContact O-CG2 3.35Å; I375-V379 PolarHBondContact O-N 3.08Å; I375-M459 HydrophobicContact CB-SD 4.39Å; I375-M459 HydrophobicContact CG1-CG 3.71Å; I375-M459 HydrophobicContact CG1-SD 3.69Å
376	G	96.9	Very high	95.6	Very high	21 Å²	21	51.3 Å²	51.3	22%	0.216	29%	0.294	C	S	.	.	H	α-helix	trans	-57.1	-46.4	178.5	0	0	0	0	0	113.1	V372 C373 V379 C380	V372-G376 PolarHBondContact O-N 3.44Å; C373-G376 PolarHBondContact O-N 3.24Å; G376-V379 PolarHBondContact O-N 3.39Å; G376-C380 PolarHBondContact O-N 3.4Å; G376-C380 PolarHBondContact O-SG 2.89Å
377	L	95.9	Very high	95.3	Very high	2 Å²	2	54.5 Å²	54.5	1%	0.01	31%	0.307	C	S	.	.	H	α-helix	trans	-63.1	-44.3	177.3	-71.9	165.8	0	0	0	111.9	C373 H374 I375 V379 C380 E381 T391 L394 V395 W455	C373-L377 WeakPolarHBondContact O-CG 3.44Å; C373-L377 PolarHBondContact O-N 3.02Å; H374-L377 PolarHBondContact O-N 3.33Å; I375-L377 PolarHBondContact O-N 2.96Å; L377-V379 PolarHBondContact O-N 2.86Å; L377-C380 PolarHBondContact O-N 3.3Å; L377-E381 PolarHBondContact O-N 3.43Å; L377-E381 VanDerWaalsContact O-N 3.07Å; L377-T391 HydrophobicContact CD2-CG2 3.88Å; L377-L394 HydrophobicContact CD1-CB 4.26Å; L377-L394 HydrophobicContact CD2-CB 3.85Å; L377-L394 HydrophobicContact CD2-CD1 4.11Å; L377-L394 HydrophobicContact CG-CB 3.84Å; L377-L394 HydrophobicContact CG-CD1 4.11Å; L377-V395 HydrophobicContact CD1-CG2 4.11Å; L377-V395 HydrophobicContact CD2-CG2 4.05Å; L377-W455 HydrophobicContact CB-CB 4.15Å; L377-W455 HydrophobicContact CB-CD2 3.96Å; L377-W455 HydrophobicContact CB-CE3 4.24Å; L377-W455 HydrophobicContact CB-CG 3.93Å; L377-W455 HydrophobicContact CD1-CD2 4.14Å; L377-W455 HydrophobicContact CD1-CE3 3.65Å; L377-W455 HydrophobicContact CD1-CH2 4.22Å; L377-W455 HydrophobicContact CD1-CZ3 3.7Å; L377-W455 HydrophobicContact CG-CE3 4.5Å
378	T	96.1	Very high	95	Very high	13 Å²	13	57.3 Å²	57.3	8%	0.08	33%	0.326	C	S	.	.	H	α-helix	trans	-60.8	-45.4	177.2	-58	0	0	0	0	111.2	H374 I375 E381 F382 W455 F456	H374-T378 VanDerWaalsContact O-CB 3.28Å; H374-T378 WeakPolarHBondContact O-CB 3.35Å; H374-T378 PolarHBondContact O-N 3.32Å; H374-T378 PolarHBondContact O-OG1 3.19Å; I375-T378 PolarHBondContact O-N 3.18Å; T378-E381 PolarHBondContact O-N 3.33Å; T378-F382 VanDerWaalsContact O-CB 3.27Å; T378-F382 WeakPolarHBondContact O-CB 3.4Å; T378-F382 PolarHBondContact O-N 3.26Å; T378-W455 WeakPolarHBondContact OG1-CB 3.32Å; T378-W455 PolarHBondContact OG1-O 3.11Å; T378-F456 HydrophobicContact CG2-CB 3.96Å; T378-F456 HydrophobicContact CG2-CD2 3.92Å; T378-F456 HydrophobicContact CG2-CG 4.45Å; T378-F456 PolarHBondContact OG1-N 3.31Å
379	V	96.3	Very high	94.7	Very high	72 Å²	72	60.6 Å²	60.6	44%	0.436	34%	0.34	S	S	.	.	H	α-helix	trans	-64.9	-43.2	178.9	171.3	0	0	0	0	111.2	I375 G376 L377 E381 F382 L383	I375-V379 HydrophobicContact CG2-CG2 4.31Å; I375-V379 WeakPolarHBondContact O-CB 3.29Å; I375-V379 VanDerWaalsContact O-CG2 3.29Å; I375-V379 WeakPolarHBondContact O-CG2 3.35Å; I375-V379 PolarHBondContact O-N 3.08Å; G376-V379 PolarHBondContact O-N 3.39Å; L377-V379 PolarHBondContact O-N 2.86Å; V379-E381 PolarHBondContact O-N 3.42Å; V379-F382 PolarHBondContact O-N 3.49Å; V379-L383 HydrophobicContact CG1-CD1 3.66Å; V379-L383 HydrophobicContact CG1-CG 4.25Å; V379-L383 WeakPolarHBondContact O-CB 3.47Å; V379-L383 VanDerWaalsContact O-CG 3.31Å; V379-L383 WeakPolarHBondContact O-CG 3.27Å; V379-L383 PolarHBondContact O-N 2.86Å
380	C	94.8	Very high	94.6	Very high	13 Å²	13	61.3 Å²	61.3	9%	0.088	34%	0.341	C	S	.	.	H	α-helix	trans	-59.3	-46.8	177.6	-68.1	0	0	0	0	111.7	G376 L377 G384 V385	G376-C380 PolarHBondContact O-N 3.4Å; G376-C380 PolarHBondContact O-SG 2.89Å; L377-C380 PolarHBondContact O-N 3.3Å; C380-G384 PolarHBondContact O-N 3.01Å; C380-G384 VanDerWaalsContact O-N 3.13Å; C380-V385 PolarHBondContact O-N 2.93Å
381	E	93	Very high	94.4	Very high	68 Å²	68	62.5 Å²	62.5	32%	0.318	35%	0.348	S	S	.	.	H	α-helix	trans	-69.4	-37.5	178.9	-71.1	-65.1	162.7	0	0	112.7	L377 T378 V379 G384 P452	L377-E381 PolarHBondContact O-N 3.43Å; L377-E381 VanDerWaalsContact O-N 3.07Å; T378-E381 PolarHBondContact O-N 3.33Å; V379-E381 PolarHBondContact O-N 3.42Å; E381-G384 PolarHBondContact O-N 3.42Å; E381-P452 HydrophobicContact CB-CB 3.78Å
382	F	93.8	Very high	94.2	Very high	153 Å²	153	63.3 Å²	63.3	67%	0.671	35%	0.353	S	S	*	.	H	α-helix	trans	-67.3	-37.8	178.3	-163.3	-90.2	0	0	0	112.2	T378 V379 G384 P452	T378-F382 VanDerWaalsContact O-CB 3.27Å; T378-F382 WeakPolarHBondContact O-CB 3.4Å; T378-F382 PolarHBondContact O-N 3.26Å; V379-F382 PolarHBondContact O-N 3.49Å; F382-G384 VanDerWaalsContact C-N 3.29Å; F382-P452 HydrophobicContact CD2-CG 4.38Å
383	L	94.5	Very high	94.1	Very high	119 Å²	119	63.1 Å²	63.1	62%	0.623	35%	0.354	S	S	*	.	T	Hydrogen-bonded Turn	trans	-82.9	-3.4	176.7	-63.2	178	0	0	0	113.2	V379 V385	V379-L383 HydrophobicContact CG1-CD1 3.66Å; V379-L383 HydrophobicContact CG1-CG 4.25Å; V379-L383 WeakPolarHBondContact O-CB 3.47Å; V379-L383 VanDerWaalsContact O-CG 3.31Å; V379-L383 WeakPolarHBondContact O-CG 3.27Å; V379-L383 PolarHBondContact O-N 2.86Å; L383-V385 HydrophobicContact CB-CG2 3.71Å; L383-V385 PolarHBondContact O-N 3.3Å
384	G	90.5	Very high	94	Very high	57 Å²	57	64 Å²	64	59%	0.588	36%	0.358	S	S	*	.	T	Hydrogen-bonded Turn	trans	64.1	24.5	-176.6	0	0	0	0	0	113.8	C380 E381 F382 V386	C380-G384 PolarHBondContact O-N 3.01Å; C380-G384 VanDerWaalsContact O-N 3.13Å; E381-G384 PolarHBondContact O-N 3.42Å; F382-G384 VanDerWaalsContact C-N 3.29Å; G384-V386 PolarHBondContact O-N 3.44Å
385	V	90.1	Very high	94	Very high	59 Å²	59	64 Å²	64	36%	0.358	36%	0.358	S	S	.	.			trans	-82.4	110.7	-175.3	175.7	0	0	0	0	110.1	C380 L383 M387	C380-V385 PolarHBondContact O-N 2.93Å; L383-V385 HydrophobicContact CB-CG2 3.71Å; L383-V385 PolarHBondContact O-N 3.3Å; V385-M387 HydrophobicContact CG1-CB 4.43Å; V385-M387 HydrophobicContact CG1-CE 3.48Å; V385-M387 VanDerWaalsContact CG1-CE 3.48Å; V385-M387 HydrophobicContact CG1-CG 3.75Å; V385-M387 HydrophobicContact CG1-SD 4.29Å; V385-M387 PolarHBondContact O-N 3Å
386	V	86.6	Confident	93.9	Very high	131 Å²	131	61.8 Å²	61.8	79%	0.794	35%	0.346	S	S	*	.			trans	-89.5	86.7	179.2	-172	0	0	0	0	110	G384 P388	G384-V386 PolarHBondContact O-N 3.44Å; V386-P388 HydrophobicContact CG1-CG 4.47Å; V386-P388 WeakPolarHBondContact O-CD 3.35Å
387	M	90.8	Very high	93.9	Very high	90 Å²	90	63.8 Å²	63.8	44%	0.443	35%	0.354	S	S	.	.			trans	-117.3	85.4	173.2	-75	-165.6	-76.4	0	0	111.2	V385 K389 L390 T391	V385-M387 HydrophobicContact CG1-CB 4.43Å; V385-M387 HydrophobicContact CG1-CE 3.48Å; V385-M387 VanDerWaalsContact CG1-CE 3.48Å; V385-M387 HydrophobicContact CG1-CG 3.75Å; V385-M387 HydrophobicContact CG1-SD 4.29Å; V385-M387 PolarHBondContact O-N 3Å; M387-K389 VanDerWaalsContact C-N 3.32Å; M387-K389 PolarHBondContact O-N 3.46Å; M387-L390 HydrophobicContact CB-CB 3.86Å; M387-L390 HydrophobicContact CE-CD2 3.37Å; M387-L390 PolarHBondContact O-N 2.83Å; M387-L390 HydrophobicContact SD-CD2 4.3Å; M387-T391 PolarHBondContact O-N 3.15Å; M387-T391 PolarHBondContact O-OG1 3Å
388	P	90.6	Very high	94	Very high	63 Å²	63	63.7 Å²	63.7	41%	0.409	35%	0.354	S	S	.	.	H	α-helix	trans	-57.2	-40.9	-171	-25.6	33.4	0	0	0	114	S326 V386 L390 T391 I392	S326-P388 WeakPolarHBondContact OG-CB 3.22Å; V386-P388 HydrophobicContact CG1-CG 4.47Å; V386-P388 WeakPolarHBondContact O-CD 3.35Å; P388-L390 VanDerWaalsContact C-N 3.35Å; P388-L390 PolarHBondContact O-N 2.9Å; P388-T391 PolarHBondContact O-N 3.46Å; P388-I392 WeakPolarHBondContact O-CB 3.5Å; P388-I392 WeakPolarHBondContact O-CD1 3.31Å; P388-I392 VanDerWaalsContact O-CG1 3.24Å; P388-I392 WeakPolarHBondContact O-CG1 3.43Å; P388-I392 PolarHBondContact O-N 3.4Å
389	K	93.3	Very high	94	Very high	186 Å²	186	63.1 Å²	63.1	81%	0.809	35%	0.35	S	S	*	.	H	α-helix	trans	-63.1	-40.1	178.1	-66.5	-177.3	-179.6	178	0	112.3	M387 S393	M387-K389 VanDerWaalsContact C-N 3.32Å; M387-K389 PolarHBondContact O-N 3.46Å; K389-S393 WeakPolarHBondContact O-CB 3.35Å; K389-S393 PolarHBondContact O-N 3.39Å
390	L	94.8	Very high	94	Very high	66 Å²	66	60.2 Å²	60.2	35%	0.346	33%	0.334	S	S	.	.	H	α-helix	trans	-68.3	-46.7	177.4	179.8	62.4	0	0	0	110.4	M387 P388 I392 S393 L394	M387-L390 HydrophobicContact CB-CB 3.86Å; M387-L390 HydrophobicContact CE-CD2 3.37Å; M387-L390 PolarHBondContact O-N 2.83Å; M387-L390 HydrophobicContact SD-CD2 4.3Å; P388-L390 VanDerWaalsContact C-N 3.35Å; P388-L390 PolarHBondContact O-N 2.9Å; L390-I392 PolarHBondContact O-N 3.4Å; L390-S393 PolarHBondContact O-N 2.98Å; L390-L394 HydrophobicContact CD1-CD1 4.14Å; L390-L394 HydrophobicContact CD1-CG 4.14Å; L390-L394 HydrophobicContact CG-CD1 3.93Å; L390-L394 HydrophobicContact CG-CG 4.35Å; L390-L394 WeakPolarHBondContact O-CG 3.25Å; L390-L394 PolarHBondContact O-N 3.27Å
391	T	94	Very high	94.1	Very high	27 Å²	27	60 Å²	60	17%	0.166	33%	0.333	C	S	.	.	H	α-helix	trans	-57.5	-47.9	177.2	-53.9	0	0	0	0	111.3	L325 L377 M387 P388 S393 L394 V395	L325-T391 HydrophobicContact CD1-CG2 4.11Å; L377-T391 HydrophobicContact CD2-CG2 3.88Å; M387-T391 PolarHBondContact O-N 3.15Å; M387-T391 PolarHBondContact O-OG1 3Å; P388-T391 PolarHBondContact O-N 3.46Å; T391-S393 PolarHBondContact O-N 3.37Å; T391-L394 PolarHBondContact O-N 3.29Å; T391-V395 HydrophobicContact CG2-CG2 4.49Å; T391-V395 WeakPolarHBondContact O-CB 3.19Å; T391-V395 VanDerWaalsContact O-CG2 3.31Å; T391-V395 WeakPolarHBondContact O-CG2 3.41Å; T391-V395 PolarHBondContact O-N 3.36Å
392	I	94.8	Very high	94.2	Very high	40 Å²	40	56.7 Å²	56.7	21%	0.205	32%	0.317	C	S	.	.	H	α-helix	trans	-57.1	-48.5	175.4	-70.7	161.3	0	0	0	110.9	L325 S326 P388 L390 L394 V395 F396	L325-I392 HydrophobicContact CD1-CG1 4.15Å; L325-I392 HydrophobicContact CD2-CB 4.31Å; L325-I392 HydrophobicContact CD2-CG1 3.68Å; L325-I392 HydrophobicContact CD2-CG2 4.37Å; L325-I392 HydrophobicContact CG-CG1 3.63Å; S326-I392 WeakPolarHBondContact OG-CD1 3.26Å; P388-I392 WeakPolarHBondContact O-CB 3.5Å; P388-I392 WeakPolarHBondContact O-CD1 3.31Å; P388-I392 VanDerWaalsContact O-CG1 3.24Å; P388-I392 WeakPolarHBondContact O-CG1 3.43Å; P388-I392 PolarHBondContact O-N 3.4Å; L390-I392 PolarHBondContact O-N 3.4Å; I392-L394 PolarHBondContact O-N 2.72Å; I392-V395 PolarHBondContact O-N 3.01Å; I392-F396 HydrophobicContact CG2-CD2 3.79Å; I392-F396 HydrophobicContact CG2-CE2 3.65Å; I392-F396 HydrophobicContact CG2-CG 4.43Å; I392-F396 HydrophobicContact CG2-CZ 4.18Å; I392-F396 WeakPolarHBondContact O-CB 3.46Å; I392-F396 PolarHBondContact O-N 2.93Å
393	S	95.9	Very high	94.1	Very high	65 Å²	65	49.5 Å²	49.5	46%	0.455	29%	0.286	S	S	.	.	H	α-helix	trans	-59.9	-46.5	179.9	-170.9	0	0	0	0	111.5	K389 L390 T391 F396 T397	K389-S393 WeakPolarHBondContact O-CB 3.35Å; K389-S393 PolarHBondContact O-N 3.39Å; L390-S393 PolarHBondContact O-N 2.98Å; T391-S393 PolarHBondContact O-N 3.37Å; S393-F396 PolarHBondContact O-N 3.18Å; S393-T397 VanDerWaalsContact O-CB 3.3Å; S393-T397 WeakPolarHBondContact O-CB 3.47Å; S393-T397 PolarHBondContact O-N 3.25Å; S393-T397 PolarHBondContact O-OG1 3.37Å
394	L	96.8	Very high	93.9	Very high	26 Å²	26	43.9 Å²	43.9	14%	0.136	26%	0.257	C	S	.	.	H	α-helix	trans	-64.3	-43	-179.5	-68.5	171.1	0	0	0	111.9	C373 L377 L390 T391 I392 A398	C373-L394 HydrophobicContact CB-CD2 4.39Å; L377-L394 HydrophobicContact CD1-CB 4.26Å; L377-L394 HydrophobicContact CD2-CB 3.85Å; L377-L394 HydrophobicContact CD2-CD1 4.11Å; L377-L394 HydrophobicContact CG-CB 3.84Å; L377-L394 HydrophobicContact CG-CD1 4.11Å; L390-L394 HydrophobicContact CD1-CD1 4.14Å; L390-L394 HydrophobicContact CD1-CG 4.14Å; L390-L394 HydrophobicContact CG-CD1 3.93Å; L390-L394 HydrophobicContact CG-CG 4.35Å; L390-L394 WeakPolarHBondContact O-CG 3.25Å; L390-L394 PolarHBondContact O-N 3.27Å; T391-L394 PolarHBondContact O-N 3.29Å; I392-L394 PolarHBondContact O-N 2.72Å; L394-A398 VanDerWaalsContact O-CB 3.28Å; L394-A398 WeakPolarHBondContact O-CB 3.37Å; L394-A398 PolarHBondContact O-N 2.97Å
395	V	96.1	Very high	94.1	Very high	0 Å²	0	41.3 Å²	41.3	0%	0	23%	0.229	C	C	.	.	H	α-helix	trans	-62.6	-47.6	177.2	170	0	0	0	0	110.9	L318 L325 L377 T391 I392 A398 A399 W455	L318-V395 HydrophobicContact CD2-CB 4.46Å; L318-V395 HydrophobicContact CD2-CG1 4.04Å; L325-V395 HydrophobicContact CD1-CB 4.5Å; L325-V395 HydrophobicContact CD1-CG2 4.14Å; L377-V395 HydrophobicContact CD1-CG2 4.11Å; L377-V395 HydrophobicContact CD2-CG2 4.05Å; T391-V395 HydrophobicContact CG2-CG2 4.49Å; T391-V395 WeakPolarHBondContact O-CB 3.19Å; T391-V395 VanDerWaalsContact O-CG2 3.31Å; T391-V395 WeakPolarHBondContact O-CG2 3.41Å; T391-V395 PolarHBondContact O-N 3.36Å; I392-V395 PolarHBondContact O-N 3.01Å; V395-A398 PolarHBondContact O-N 2.87Å; V395-A399 VanDerWaalsContact O-CB 3.23Å; V395-A399 WeakPolarHBondContact O-CB 3.24Å; V395-A399 PolarHBondContact O-N 3.19Å; V395-W455 HydrophobicContact CG2-CH2 4.09Å
396	F	96.6	Very high	94.2	Very high	26 Å²	26	41 Å²	41	11%	0.114	22%	0.222	C	C	.	.	H	α-helix	trans	-69.3	-39.6	-179.5	-72.3	-7	0	0	0	112.8	L322 L325 N332 F335 Y336 I339 I392 S393 A399 A400	L322-F396 HydrophobicContact CD2-CE1 3.81Å; L325-F396 HydrophobicContact CD2-CE1 4.01Å; L325-F396 HydrophobicContact CD2-CZ 4.21Å; N332-F396 HydrophobicContact CB-CZ 4.47Å; F335-F396 HydrophobicContact CB-CE2 4.02Å; F335-F396 HydrophobicContact CB-CZ 4.23Å; Y336-F396 HydrophobicContact CD2-CD1 4.32Å; Y336-F396 HydrophobicContact CD2-CE1 4.43Å; I339-F396 HydrophobicContact CD1-CB 4.42Å; I339-F396 HydrophobicContact CD1-CD2 4.18Å; I339-F396 HydrophobicContact CD1-CG 4.48Å; I392-F396 HydrophobicContact CG2-CD2 3.79Å; I392-F396 HydrophobicContact CG2-CE2 3.65Å; I392-F396 HydrophobicContact CG2-CG 4.43Å; I392-F396 HydrophobicContact CG2-CZ 4.18Å; I392-F396 WeakPolarHBondContact O-CB 3.46Å; I392-F396 PolarHBondContact O-N 2.93Å; S393-F396 PolarHBondContact O-N 3.18Å; F396-A399 PolarHBondContact O-N 3.47Å; F396-A400 VanDerWaalsContact O-CB 3.26Å; F396-A400 WeakPolarHBondContact O-CB 3.26Å; F396-A400 PolarHBondContact O-N 2.93Å
397	T	97.4	Very high	94.2	Very high	63 Å²	63	35.9 Å²	35.9	39%	0.387	19%	0.19	S	C	.	.	H	α-helix	trans	-63.3	-44.5	174.7	-60.6	0	0	0	0	111.3	V369 S393 A400 A401	V369-T397 HydrophobicContact CG1-CG2 3.69Å; S393-T397 VanDerWaalsContact O-CB 3.3Å; S393-T397 WeakPolarHBondContact O-CB 3.47Å; S393-T397 PolarHBondContact O-N 3.25Å; S393-T397 PolarHBondContact O-OG1 3.37Å; T397-A400 PolarHBondContact O-N 3.4Å; T397-A401 PolarHBondContact O-N 3.43Å; T397-A401 VanDerWaalsContact O-N 3.16Å
398	A	97.6	Very high	94.1	Very high	0 Å²	0	32.1 Å²	32.1	0%	0	17%	0.173	C	C	.	.	H	α-helix	trans	-61.1	-47.8	174.7	0	0	0	0	0	111.3	L318 C373 L394 V395 A400 A401 T402	L318-A398 HydrophobicContact CD1-CB 3.9Å; L318-A398 HydrophobicContact CD2-CB 4Å; C373-A398 HydrophobicContact CB-CB 3.71Å; L394-A398 VanDerWaalsContact O-CB 3.28Å; L394-A398 WeakPolarHBondContact O-CB 3.37Å; L394-A398 PolarHBondContact O-N 2.97Å; V395-A398 PolarHBondContact O-N 2.87Å; A398-A400 PolarHBondContact O-N 3.14Å; A398-A401 PolarHBondContact O-N 2.9Å; A398-T402 WeakPolarHBondContact O-CG2 3.43Å; A398-T402 PolarHBondContact O-N 3.18Å; A398-T402 VanDerWaalsContact O-N 3.16Å
399	A	95.6	Very high	94.1	Very high	1 Å²	1	29.1 Å²	29.1	1%	0.008	15%	0.153	C	C	.	.	H	α-helix	trans	-59.2	-46.2	179.7	0	0	0	0	0	111.9	L318 Y336 R340 V395 F396 A401 T402	L318-A399 HydrophobicContact CD1-CB 4.37Å; Y336-A399 HydrophobicContact CD2-CB 3.65Å; Y336-A399 HydrophobicContact CE2-CB 3.25Å; R340-A399 HydrophobicContact CG-CB 4.26Å; V395-A399 VanDerWaalsContact O-CB 3.23Å; V395-A399 WeakPolarHBondContact O-CB 3.24Å; V395-A399 PolarHBondContact O-N 3.19Å; F396-A399 PolarHBondContact O-N 3.47Å; A399-A401 VanDerWaalsContact C-N 3.28Å; A399-A401 PolarHBondContact O-N 2.88Å; A399-T402 PolarHBondContact O-N 2.75Å; A399-T402 VanDerWaalsContact O-N 3.12Å; A399-T402 PolarHBondContact O-OG1 3.37Å
400	A	95.8	Very high	93.7	Very high	12 Å²	12	23.1 Å²	23.1	10%	0.099	13%	0.134	C	C	.	.	H	α-helix	trans	-55	-44.7	176.4	0	0	0	0	0	111.9	I339 V343 F396 T397 A398 T402 P404	I339-A400 HydrophobicContact CG2-CB 3.5Å; V343-A400 HydrophobicContact CB-CB 4.47Å; V343-A400 WeakPolarHBondContact CG1-O 3.48Å; V343-A400 HydrophobicContact CG2-CB 4.12Å; F396-A400 VanDerWaalsContact O-CB 3.26Å; F396-A400 WeakPolarHBondContact O-CB 3.26Å; F396-A400 PolarHBondContact O-N 2.93Å; T397-A400 PolarHBondContact O-N 3.4Å; A398-A400 PolarHBondContact O-N 3.14Å; A400-T402 VanDerWaalsContact C-N 3.32Å; A400-T402 PolarHBondContact O-N 2.9Å; A400-P404 WeakPolarHBondContact O-CD 3.5Å
401	A	96.3	Very high	93.2	Very high	7 Å²	7	21.8 Å²	21.8	6%	0.058	13%	0.128	C	C	.	.	H	α-helix	trans	-69.4	-25.1	-179.8	0	0	0	0	0	113.3	C366 V369 V370 T397 A398 A399 S403 I405	C366-A401 HydrophobicContact CB-CB 4.19Å; V369-A401 HydrophobicContact CB-CB 4.3Å; V369-A401 HydrophobicContact CG1-CB 4.09Å; V370-A401 HydrophobicContact CG2-CB 3.69Å; T397-A401 PolarHBondContact O-N 3.43Å; T397-A401 VanDerWaalsContact O-N 3.16Å; A398-A401 PolarHBondContact O-N 2.9Å; A399-A401 VanDerWaalsContact C-N 3.28Å; A399-A401 PolarHBondContact O-N 2.88Å; A401-S403 PolarHBondContact O-N 2.77Å; A401-I405 VanDerWaalsContact O-CD1 3.27Å; A401-I405 WeakPolarHBondContact O-CD1 3.48Å; A401-I405 VanDerWaalsContact O-CG1 3.23Å; A401-I405 WeakPolarHBondContact O-CG1 3.43Å
402	T	95.5	Very high	92.9	Very high	0 Å²	0	20.6 Å²	20.6	0%	0	12%	0.12	C	C	.	.	H	α-helix	trans	-67.9	-32	178.5	65.5	0	0	0	0	114.2	L311 I314 L318 R340 V370 A398 A399 A400 I405 W406	L311-T402 HydrophobicContact CD1-CG2 4.2Å; I314-T402 HydrophobicContact CG2-CG2 3.93Å; L318-T402 HydrophobicContact CD1-CG2 4.03Å; R340-T402 PolarHBondContact NH1-OG1 2.8Å; R340-T402 VanDerWaalsContact NH1-OG1 3.15Å; R340-T402 PolarHBondContact NH2-OG1 3.49Å; V370-T402 HydrophobicContact CG2-CG2 4.2Å; A398-T402 WeakPolarHBondContact O-CG2 3.43Å; A398-T402 PolarHBondContact O-N 3.18Å; A398-T402 VanDerWaalsContact O-N 3.16Å; A399-T402 PolarHBondContact O-N 2.75Å; A399-T402 VanDerWaalsContact O-N 3.12Å; A399-T402 PolarHBondContact O-OG1 3.37Å; A400-T402 VanDerWaalsContact C-N 3.32Å; A400-T402 PolarHBondContact O-N 2.9Å; T402-I405 WeakPolarHBondContact O-CB 3.46Å; T402-I405 PolarHBondContact O-N 3.37Å; T402-W406 PolarHBondContact O-N 3.02Å
403	S	91.7	Very high	92.5	Very high	1 Å²	1	18.8 Å²	18.8	1%	0.007	11%	0.111	C	C	.	.	H	α-helix	trans	-70.2	-46.1	-173.6	-64.4	0	0	0	0	114.2	N195 R340 A401 I405 W406 N407	N195-S403 PolarHBondContact OD1-OG 3.4Å; N195-S403 VanDerWaalsContact OD1-OG 3.14Å; R340-S403 WeakPolarHBondContact CB-OG 3.34Å; R340-S403 PolarHBondContact NE-OG 3.5Å; R340-S403 VanDerWaalsContact NE-OG 3.14Å; R340-S403 PolarHBondContact NH2-OG 2.91Å; R340-S403 WeakPolarHBondContact O-CB 3.31Å; R340-S403 PolarHBondContact O-OG 3.13Å; A401-S403 PolarHBondContact O-N 2.77Å; S403-I405 PolarHBondContact O-N 3.44Å; S403-W406 WeakPolarHBondContact O-CB 3.44Å; S403-W406 PolarHBondContact O-N 3.44Å; S403-W406 VanDerWaalsContact O-N 3.17Å; S403-N407 PolarHBondContact O-N 3.04Å
404	P	91.6	Very high	91.8	Very high	2 Å²	2	18.5 Å²	18.5	1%	0.013	11%	0.106	C	C	.	.	H	α-helix	trans	-57.8	-36.6	171.1	-26.8	35	0	0	0	113.5	V343 A347 I362 A400 N407 S408	V343-P404 HydrophobicContact CG1-CG 3.63Å; A347-P404 HydrophobicContact CB-CB 3.63Å; A347-P404 HydrophobicContact CB-CG 3.72Å; I362-P404 HydrophobicContact CG2-CB 4.14Å; A400-P404 WeakPolarHBondContact O-CD 3.5Å; P404-N407 PolarHBondContact O-N 3.11Å; P404-S408 VanDerWaalsContact O-CB 3.27Å; P404-S408 WeakPolarHBondContact O-CB 3.5Å; P404-S408 PolarHBondContact O-N 3.42Å; P404-S408 PolarHBondContact O-OG 3.05Å
405	I	94.2	Very high	91.2	Very high	2 Å²	2	19.1 Å²	19.1	1%	0.01	11%	0.109	C	C	.	.	H	α-helix	trans	-62.3	-46.3	176.7	-60.1	168.7	0	0	0	109.2	L311 I363 C366 V370 A401 T402 S403 N407 S408 I409 F465	L311-I405 HydrophobicContact CD1-CB 4.16Å; L311-I405 HydrophobicContact CD1-CD1 4.45Å; L311-I405 HydrophobicContact CD1-CG2 3.97Å; L311-I405 HydrophobicContact CD2-CB 4.27Å; L311-I405 HydrophobicContact CD2-CG2 3.65Å; L311-I405 HydrophobicContact CG-CG2 4.43Å; I363-I405 HydrophobicContact CG2-CG2 4.38Å; C366-I405 HydrophobicContact CB-CD1 3.7Å; C366-I405 HydrophobicContact CB-CG1 3.48Å; C366-I405 VanDerWaalsContact CB-CG1 3.48Å; V370-I405 HydrophobicContact CG2-CD1 4.24Å; A401-I405 VanDerWaalsContact O-CD1 3.27Å; A401-I405 WeakPolarHBondContact O-CD1 3.48Å; A401-I405 VanDerWaalsContact O-CG1 3.23Å; A401-I405 WeakPolarHBondContact O-CG1 3.43Å; T402-I405 WeakPolarHBondContact O-CB 3.46Å; T402-I405 PolarHBondContact O-N 3.37Å; S403-I405 PolarHBondContact O-N 3.44Å; I405-N407 PolarHBondContact O-N 3.25Å; I405-S408 PolarHBondContact O-N 2.96Å; I405-I409 HydrophobicContact CG2-CD1 3.52Å; I405-I409 HydrophobicContact CG2-CG1 3.95Å; I405-I409 VanDerWaalsContact O-CB 3.27Å; I405-I409 WeakPolarHBondContact O-CB 3.43Å; I405-I409 WeakPolarHBondContact O-CG1 3.21Å; I405-I409 PolarHBondContact O-N 3.31Å; I405-F465 HydrophobicContact CG2-CE1 4.08Å; I405-F465 HydrophobicContact CG2-CZ 3.83Å
406	W	91.5	Very high	90.7	Very high	54 Å²	54	19.8 Å²	19.8	21%	0.205	11%	0.112	C	C	.	.	H	α-helix	trans	-56.5	-47.8	178.5	-102.9	141.3	0	0	0	112.8	M308 L311 T402 S403 S410 I433	M308-W406 HydrophobicContact CE-CZ3 4.18Å; M308-W406 HydrophobicContact SD-CE3 4.24Å; M308-W406 HydrophobicContact SD-CH2 3.68Å; M308-W406 HydrophobicContact SD-CZ3 3.19Å; M308-W406 WeakPolarHBondContact SD-CZ3 3.48Å; L311-W406 HydrophobicContact CB-CH2 4.41Å; L311-W406 HydrophobicContact CB-CZ2 4.16Å; L311-W406 HydrophobicContact CD2-CB 4.4Å; L311-W406 HydrophobicContact CD2-CD2 3.33Å; L311-W406 HydrophobicContact CD2-CE3 3.54Å; L311-W406 HydrophobicContact CD2-CG 3.79Å; L311-W406 HydrophobicContact CD2-CH2 3.92Å; L311-W406 HydrophobicContact CD2-CZ2 3.78Å; L311-W406 HydrophobicContact CD2-CZ3 3.86Å; L311-W406 HydrophobicContact CG-CD2 3.99Å; L311-W406 HydrophobicContact CG-CG 4.37Å; L311-W406 HydrophobicContact CG-CH2 4.27Å; L311-W406 HydrophobicContact CG-CZ2 3.76Å; T402-W406 PolarHBondContact O-N 3.02Å; S403-W406 WeakPolarHBondContact O-CB 3.44Å; S403-W406 PolarHBondContact O-N 3.44Å; S403-W406 VanDerWaalsContact O-N 3.17Å; W406-S410 WeakPolarHBondContact O-CB 3.28Å; W406-S410 PolarHBondContact O-N 3.42Å; W406-S410 VanDerWaalsContact O-N 3.16Å; W406-S410 PolarHBondContact O-OG 2.94Å; W406-I433 HydrophobicContact CH2-CD1 3.59Å; W406-I433 HydrophobicContact CH2-CG1 3.92Å; W406-I433 HydrophobicContact CH2-CG2 4.37Å; W406-I433 HydrophobicContact CZ3-CD1 3.94Å
407	N	87.3	Confident	90.1	Very high	23 Å²	23	18.6 Å²	18.6	12%	0.123	11%	0.107	C	C	.	.	H	α-helix	trans	-66.6	-46.1	-179.5	-69.5	0.8	0	0	0	111.5	L186 S190 S403 P404 I405 S410 L411	L186-N407 HydrophobicContact CD1-CB 4.12Å; S190-N407 PolarHBondContact OG-ND2 3.34Å; S403-N407 PolarHBondContact O-N 3.04Å; P404-N407 PolarHBondContact O-N 3.11Å; I405-N407 PolarHBondContact O-N 3.25Å; N407-S410 PolarHBondContact O-N 3.23Å; N407-L411 PolarHBondContact O-N 3.49Å
408	S	89	Confident	89.1	Confident	11 Å²	11	15.6 Å²	15.6	8%	0.077	9%	0.089	C	C	.	.	H	α-helix	trans	-68	-45.7	-176.5	-57.2	0	0	0	0	111.8	P404 I405 S410 L411 V412	P404-S408 VanDerWaalsContact O-CB 3.27Å; P404-S408 WeakPolarHBondContact O-CB 3.5Å; P404-S408 PolarHBondContact O-N 3.42Å; P404-S408 PolarHBondContact O-OG 3.05Å; I405-S408 PolarHBondContact O-N 2.96Å; S408-S410 VanDerWaalsContact C-N 3.33Å; S408-S410 PolarHBondContact O-N 2.93Å; S408-L411 PolarHBondContact O-N 3.48Å; S408-V412 WeakPolarHBondContact O-CG2 3.44Å; S408-V412 PolarHBondContact O-N 3.48Å
409	I	90.6	Very high	87.9	Confident	0 Å²	0	18.8 Å²	18.8	0%	0	11%	0.108	C	C	.	.	H	α-helix	trans	-60.1	-44.8	176.9	-77.2	-178.5	0	0	0	110.7	M304 M308 L311 I363 I405 L411 V412 V413 F465	M304-I409 HydrophobicContact CE-CG2 3.68Å; M308-I409 HydrophobicContact CE-CG2 3.15Å; M308-I409 HydrophobicContact CG-CG2 4.35Å; M308-I409 HydrophobicContact SD-CG2 3.37Å; M308-I409 WeakPolarHBondContact SD-CG2 3.12Å; L311-I409 HydrophobicContact CD2-CD1 3.91Å; I363-I409 HydrophobicContact CD1-CG1 3.8Å; I363-I409 HydrophobicContact CG1-CG1 4.25Å; I363-I409 HydrophobicContact CG2-CG1 4.46Å; I405-I409 HydrophobicContact CG2-CD1 3.52Å; I405-I409 HydrophobicContact CG2-CG1 3.95Å; I405-I409 VanDerWaalsContact O-CB 3.27Å; I405-I409 WeakPolarHBondContact O-CB 3.43Å; I405-I409 WeakPolarHBondContact O-CG1 3.21Å; I405-I409 PolarHBondContact O-N 3.31Å; I409-L411 PolarHBondContact O-N 3.3Å; I409-V412 WeakPolarHBondContact O-CB 3.42Å; I409-V412 PolarHBondContact O-N 2.97Å; I409-V413 HydrophobicContact CG2-CG2 4.31Å; I409-V413 WeakPolarHBondContact O-CG2 3.49Å; I409-V413 PolarHBondContact O-N 3.01Å; I409-F465 HydrophobicContact CD1-CE1 3.66Å; I409-F465 HydrophobicContact CD1-CZ 3.43Å; I409-F465 VanDerWaalsContact CD1-CZ 3.43Å; I409-F465 HydrophobicContact CG1-CZ 4.34Å
410	S	85	Confident	86.6	Confident	59 Å²	59	19.1 Å²	19.1	41%	0.413	11%	0.11	S	C	.	.	H	α-helix	trans	-57.1	-36.1	-178.2	-62.6	0	0	0	0	111.5	W406 N407 S408	W406-S410 WeakPolarHBondContact O-CB 3.28Å; W406-S410 PolarHBondContact O-N 3.42Å; W406-S410 VanDerWaalsContact O-N 3.16Å; W406-S410 PolarHBondContact O-OG 2.94Å; N407-S410 PolarHBondContact O-N 3.23Å; S408-S410 VanDerWaalsContact C-N 3.33Å; S408-S410 PolarHBondContact O-N 2.93Å
411	L	82.9	Confident	85.6	Confident	39 Å²	39	18.9 Å²	18.9	20%	0.204	11%	0.107	C	C	.	.	H	α-helix	trans	-76.3	-39	172.8	-65.4	178.1	0	0	0	113.5	L186 N407 S408 I409 V413 V414 E415	L186-L411 HydrophobicContact CB-CD1 4.15Å; L186-L411 HydrophobicContact CD1-CD1 3.61Å; L186-L411 HydrophobicContact CD1-CG 4.32Å; L186-L411 HydrophobicContact CD2-CD1 3.76Å; L186-L411 HydrophobicContact CG-CD1 4.01Å; N407-L411 PolarHBondContact O-N 3.49Å; S408-L411 PolarHBondContact O-N 3.48Å; I409-L411 PolarHBondContact O-N 3.3Å; L411-V413 PolarHBondContact O-N 3.06Å; L411-V414 PolarHBondContact O-N 3.06Å; L411-E415 PolarHBondContact O-N 2.9Å
412	V	88.3	Confident	84.5	Confident	2 Å²	2	21 Å²	21	1%	0.012	11%	0.113	C	C	.	.	H	α-helix	trans	-56.8	-39.6	175.5	168.6	0	0	0	0	110.8	M304 R359 I363 S408 I409 V414 E415 L416 F469 I473 T476	M304-V412 HydrophobicContact CE-CB 4.47Å; M304-V412 HydrophobicContact CE-CG1 4.02Å; M304-V412 HydrophobicContact SD-CG1 4.33Å; R359-V412 HydrophobicContact CB-CG2 4.24Å; I363-V412 HydrophobicContact CD1-CG2 3.91Å; S408-V412 WeakPolarHBondContact O-CG2 3.44Å; S408-V412 PolarHBondContact O-N 3.48Å; I409-V412 WeakPolarHBondContact O-CB 3.42Å; I409-V412 PolarHBondContact O-N 2.97Å; V412-V414 VanDerWaalsContact C-N 3.31Å; V412-V414 PolarHBondContact O-N 3.41Å; V412-E415 PolarHBondContact O-N 2.89Å; V412-L416 WeakPolarHBondContact O-CB 3.47Å; V412-L416 PolarHBondContact O-N 3.22Å; V412-F469 HydrophobicContact CG1-CZ 4.4Å; V412-I473 HydrophobicContact CG1-CG2 4.11Å; V412-T476 HydrophobicContact CG1-CG2 4.2Å
413	V	86.8	Confident	83.3	Confident	2 Å²	2	25.1 Å²	25.1	1%	0.012	14%	0.143	C	C	.	.	H	α-helix	trans	-61.5	-40.1	174.5	179.6	0	0	0	0	111.5	M304 M308 I409 L411 E415 Y417 A425 P426 M429	M304-V413 HydrophobicContact CE-CG2 3.47Å; M304-V413 VanDerWaalsContact CE-CG2 3.47Å; M308-V413 HydrophobicContact CE-CG2 3.58Å; I409-V413 HydrophobicContact CG2-CG2 4.31Å; I409-V413 WeakPolarHBondContact O-CG2 3.49Å; I409-V413 PolarHBondContact O-N 3.01Å; L411-V413 PolarHBondContact O-N 3.06Å; V413-E415 VanDerWaalsContact C-N 3.32Å; V413-E415 PolarHBondContact O-N 3.26Å; V413-Y417 HydrophobicContact CG1-CD2 4.23Å; V413-Y417 HydrophobicContact CG1-CE2 4.29Å; V413-Y417 WeakPolarHBondContact O-CD2 3.39Å; V413-A425 HydrophobicContact CG1-CB 4.21Å; V413-P426 HydrophobicContact CG1-CB 4.43Å; V413-P426 HydrophobicContact CG1-CG 3.65Å; V413-M429 HydrophobicContact CB-SD 4.4Å; V413-M429 HydrophobicContact CG1-CE 4.02Å; V413-M429 HydrophobicContact CG1-SD 3.86Å; V413-M429 HydrophobicContact CG2-CE 4.17Å; V413-M429 HydrophobicContact CG2-SD 3.53Å; V413-M429 VanDerWaalsContact CG2-SD 3.53Å
414	V	81.4	Confident	82.7	Confident	59 Å²	59	26.3 Å²	26.3	36%	0.358	15%	0.149	S	C	.	.	H	α-helix	trans	-69.2	-34.2	179	177.7	0	0	0	0	111.3	L411 V412 R422	L411-V414 PolarHBondContact O-N 3.06Å; V412-V414 VanDerWaalsContact C-N 3.31Å; V412-V414 PolarHBondContact O-N 3.41Å; V414-R422 HydrophobicContact CG1-CG 4.41Å; V414-R422 WeakPolarHBondContact O-CD 3.34Å; V414-R422 WeakPolarHBondContact O-CG 3.43Å; V414-R422 PolarHBondContact O-NE 3.31Å
415	E	83.8	Confident	82.3	Confident	39 Å²	39	26.2 Å²	26.2	18%	0.182	15%	0.148	C	C	.	.	H	α-helix	trans	-85.2	-28.7	-177.3	-71.4	-179	178.3	0	0	114.6	R359 L411 V412 V413 Y417 T476 L481 P482	R359-E415 IonicContact CZ-OE1 3.47Å; R359-E415 IonicContact CZ-OE2 2.84Å; R359-E415 IonicContact NH1-OE1 2.65Å; R359-E415 PolarHBondContact NH1-OE1 3.25Å; R359-E415 IonicContact NH1-OE2 3.68Å; R359-E415 PolarHBondContact NH1-OE2 3.01Å; R359-E415 IonicContact NH2-OE1 3.71Å; R359-E415 PolarHBondContact NH2-OE1 3.25Å; R359-E415 IonicContact NH2-OE2 2.7Å; L411-E415 PolarHBondContact O-N 2.9Å; V412-E415 PolarHBondContact O-N 2.89Å; V413-E415 VanDerWaalsContact C-N 3.32Å; V413-E415 PolarHBondContact O-N 3.26Å; E415-Y417 VanDerWaalsContact C-N 3.31Å; E415-T476 HydrophobicContact CB-CG2 4.36Å; E415-T476 WeakPolarHBondContact OE2-CB 3.27Å; E415-T476 PolarHBondContact OE2-OG1 3.47Å; E415-L481 HydrophobicContact CB-CD2 4.27Å; E415-L481 HydrophobicContact CG-CD2 3.87Å; E415-P482 WeakPolarHBondContact O-CD 3.22Å; E415-P482 WeakPolarHBondContact O-CG 3.03Å
416	L	85.7	Confident	81.7	Confident	14 Å²	14	28.4 Å²	28.4	7%	0.073	16%	0.163	C	C	.	.	H	α-helix	trans	-76	-25.5	-178	-167	65.3	0	0	0	112	Y300 M304 V412 I473 P474 T476	Y300-L416 HydrophobicContact CD1-CD2 4.39Å; Y300-L416 HydrophobicContact CD2-CD1 3.62Å; Y300-L416 HydrophobicContact CD2-CD2 3.75Å; Y300-L416 HydrophobicContact CD2-CG 3.56Å; Y300-L416 HydrophobicContact CE2-CD1 3.51Å; Y300-L416 HydrophobicContact CE2-CD2 4.45Å; Y300-L416 HydrophobicContact CE2-CG 4Å; Y300-L416 HydrophobicContact CG-CD1 4.26Å; Y300-L416 HydrophobicContact CG-CD2 3.69Å; Y300-L416 HydrophobicContact CG-CG 4.07Å; M304-L416 HydrophobicContact CG-CD2 4.17Å; V412-L416 WeakPolarHBondContact O-CB 3.47Å; V412-L416 PolarHBondContact O-N 3.22Å; L416-I473 HydrophobicContact CD2-CD1 4Å; L416-P474 HydrophobicContact CD1-CG 4.18Å; L416-T476 HydrophobicContact CD1-CG2 4.46Å
417	Y	83.7	Confident	81.1	Confident	0 Å²	0	27 Å²	27	0%	0	17%	0.165	C	C	.	.	S	Bend	trans	-103.8	143.8	-174.1	-70.5	-97.3	0	0	0	112.3	L291 L297 T301 V413 E415 M421 R422 A425 M429	L291-Y417 HydrophobicContact CD2-CD1 3.96Å; L291-Y417 HydrophobicContact CD2-CE1 3.66Å; L297-Y417 HydrophobicContact CD1-CD1 3.6Å; L297-Y417 HydrophobicContact CD1-CE1 3.52Å; L297-Y417 HydrophobicContact CG-CE1 4.24Å; T301-Y417 WeakPolarHBondContact CA-OH 3.36Å; T301-Y417 WeakPolarHBondContact CB-OH 3.39Å; T301-Y417 PolarHBondContact N-OH 3.31Å; T301-Y417 PolarHBondContact OG1-OH 2.88Å; V413-Y417 HydrophobicContact CG1-CD2 4.23Å; V413-Y417 HydrophobicContact CG1-CE2 4.29Å; V413-Y417 WeakPolarHBondContact O-CD2 3.39Å; E415-Y417 VanDerWaalsContact C-N 3.31Å; Y417-M421 HydrophobicContact CD1-CB 4.18Å; Y417-M421 HydrophobicContact CD1-SD 4.34Å; Y417-R422 PolarHBondContact O-NE 2.83Å; Y417-R422 VanDerWaalsContact O-NE 3.08Å; Y417-A425 HydrophobicContact CD1-CB 3.62Å; Y417-A425 HydrophobicContact CD2-CB 3.93Å; Y417-A425 HydrophobicContact CE1-CB 3.69Å; Y417-A425 HydrophobicContact CE2-CB 3.98Å; Y417-A425 HydrophobicContact CG-CB 3.74Å; Y417-M429 HydrophobicContact CE2-CE 3.68Å; Y417-M429 VanDerWaalsContact OH-CE 3.25Å; Y417-M429 WeakPolarHBondContact OH-CE 3.26Å
418	P	77.5	Confident	81	Confident	1 Å²	1	27.6 Å²	27.6	1%	0.006	17%	0.167	C	C	.	.			trans	-58.7	152.5	170.8	-21.7	32.8	0	0	0	111.3	S420 M421 R422 P482 E487	P418-S420 PolarHBondContact O-N 2.85Å; P418-M421 PolarHBondContact O-N 3.28Å; P418-R422 WeakPolarHBondContact O-CG 3.42Å; P418-R422 PolarHBondContact O-N 3.01Å; P418-P482 HydrophobicContact CG-CB 4.39Å; P418-E487 WeakPolarHBondContact CG-OE2 3.49Å
419	T	71.8	Confident	80.9	Confident	66 Å²	66	27.1 Å²	27.1	41%	0.405	16%	0.163	S	C	.	.	G	3₁₀ helix	trans	-43.6	-42.9	177.8	46.3	0	0	0	0	113.2	M421 R422	T419-M421 PolarHBondContact O-N 3.07Å; T419-M421 VanDerWaalsContact O-N 3.12Å; T419-R422 VanDerWaalsContact CG2-NH1 3.31Å; T419-R422 PolarHBondContact O-N 3.13Å
420	S	68.8	Low	80.6	Confident	8 Å²	8	27.6 Å²	27.6	6%	0.056	17%	0.166	C	C	.	.	G	3₁₀ helix	trans	-53.9	-26.5	176.8	72.9	0	0	0	0	116	P418	P418-S420 PolarHBondContact O-N 2.85Å
421	M	73.6	Confident	80.7	Confident	7 Å²	7	27.5 Å²	27.5	3%	0.034	16%	0.161	C	C	.	.	G	3₁₀ helix	trans	-117.9	-1.9	-173.1	-59.3	-176.7	-164.6	0	0	112.9	H290 L291 L297 Y417 P418 T419 S423 I424 A425	H290-M421 HydrophobicContact CB-CE 4.03Å; H290-M421 WeakPolarHBondContact O-CE 3.38Å; L291-M421 HydrophobicContact CD2-CB 4.29Å; L291-M421 HydrophobicContact CD2-SD 4.02Å; L297-M421 HydrophobicContact CD1-SD 4.4Å; L297-M421 HydrophobicContact CD2-CE 3.63Å; L297-M421 HydrophobicContact CD2-SD 3.52Å; L297-M421 VanDerWaalsContact CD2-SD 3.52Å; L297-M421 HydrophobicContact CG-SD 4.49Å; Y417-M421 HydrophobicContact CD1-CB 4.18Å; Y417-M421 HydrophobicContact CD1-SD 4.34Å; P418-M421 PolarHBondContact O-N 3.28Å; T419-M421 PolarHBondContact O-N 3.07Å; T419-M421 VanDerWaalsContact O-N 3.12Å; M421-S423 PolarHBondContact O-N 2.64Å; M421-I424 PolarHBondContact O-N 3.08Å; M421-I424 VanDerWaalsContact O-N 3.13Å; M421-A425 WeakPolarHBondContact O-CB 3.42Å; M421-A425 PolarHBondContact O-N 3.3Å
422	R	73.8	Confident	81	Confident	51 Å²	51	29.3 Å²	29.3	19%	0.192	17%	0.167	C	C	.	.	T	Hydrogen-bonded Turn	trans	-63.9	-23.3	-175.8	-75.9	-179.9	-172.1	154.9	14	114.2	V414 Y417 P418 T419 P426 P482	V414-R422 HydrophobicContact CG1-CG 4.41Å; V414-R422 WeakPolarHBondContact O-CD 3.34Å; V414-R422 WeakPolarHBondContact O-CG 3.43Å; V414-R422 PolarHBondContact O-NE 3.31Å; Y417-R422 PolarHBondContact O-NE 2.83Å; Y417-R422 VanDerWaalsContact O-NE 3.08Å; P418-R422 WeakPolarHBondContact O-CG 3.42Å; P418-R422 PolarHBondContact O-N 3.01Å; T419-R422 VanDerWaalsContact CG2-NH1 3.31Å; T419-R422 PolarHBondContact O-N 3.13Å; R422-P426 WeakPolarHBondContact O-CD 3.39Å; R422-P426 WeakPolarHBondContact O-CG 3.2Å; R422-P482 PolarHBondContact NH2-O 3Å
423	S	70.9	Confident	81.1	Confident	88 Å²	88	30.6 Å²	30.6	62%	0.615	17%	0.173	S	C	*	.	T	Hydrogen-bonded Turn	trans	-89.8	-37	171.4	54.4	0	0	0	0	112.3	M421 G427	M421-S423 PolarHBondContact O-N 2.64Å; S423-G427 PolarHBondContact O-N 3.1Å
424	I	78.1	Confident	81.1	Confident	26 Å²	26	32.1 Å²	32.1	13%	0.133	18%	0.179	C	C	.	.	H	α-helix	trans	-71.4	-42.4	-176.3	-59	168	0	0	0	111.3	R286 F288 L291 M421 G427 F428	R286-I424 HydrophobicContact CB-CD1 3.62Å; R286-I424 WeakPolarHBondContact O-CD1 3.38Å; F288-I424 HydrophobicContact CD1-CG2 3.48Å; F288-I424 VanDerWaalsContact CD1-CG2 3.48Å; F288-I424 HydrophobicContact CE1-CG2 3.8Å; F288-I424 HydrophobicContact CG-CG2 4.41Å; L291-I424 HydrophobicContact CD1-CG2 4.17Å; L291-I424 HydrophobicContact CG-CG2 4.35Å; M421-I424 PolarHBondContact O-N 3.08Å; M421-I424 VanDerWaalsContact O-N 3.13Å; I424-G427 CarbonylContact O-C 3.58Å; I424-G427 PolarHBondContact O-N 3.41Å; I424-F428 PolarHBondContact O-N 3.09Å
425	A	83.6	Confident	81.3	Confident	0 Å²	0	31 Å²	31	0%	0	18%	0.176	C	C	.	.	H	α-helix	trans	-64.8	-51.1	-176.3	0	0	0	0	0	112.6	L291 V413 Y417 M421 G427 F428 M429	L291-A425 HydrophobicContact CD2-CB 3.75Å; V413-A425 HydrophobicContact CG1-CB 4.21Å; Y417-A425 HydrophobicContact CD1-CB 3.62Å; Y417-A425 HydrophobicContact CD2-CB 3.93Å; Y417-A425 HydrophobicContact CE1-CB 3.69Å; Y417-A425 HydrophobicContact CE2-CB 3.98Å; Y417-A425 HydrophobicContact CG-CB 3.74Å; M421-A425 WeakPolarHBondContact O-CB 3.42Å; M421-A425 PolarHBondContact O-N 3.3Å; A425-G427 VanDerWaalsContact C-N 3.27Å; A425-G427 PolarHBondContact O-N 3.18Å; A425-F428 PolarHBondContact O-N 3.24Å; A425-M429 HydrophobicContact CB-CE 4.32Å; A425-M429 VanDerWaalsContact O-CG 3.29Å; A425-M429 WeakPolarHBondContact O-CG 3.23Å; A425-M429 PolarHBondContact O-N 3.29Å
426	P	81.1	Confident	81.6	Confident	48 Å²	48	29.1 Å²	29.1	31%	0.312	17%	0.167	S	C	.	.	H	α-helix	trans	-58.7	-38.6	170.5	-20.5	30.1	0	0	0	112.6	V413 R422 F428 M429 S430	V413-P426 HydrophobicContact CG1-CB 4.43Å; V413-P426 HydrophobicContact CG1-CG 3.65Å; R422-P426 WeakPolarHBondContact O-CD 3.39Å; R422-P426 WeakPolarHBondContact O-CG 3.2Å; P426-F428 PolarHBondContact O-N 3.45Å; P426-M429 PolarHBondContact O-N 3.1Å; P426-S430 WeakPolarHBondContact O-CB 3.11Å; P426-S430 PolarHBondContact O-N 3.11Å
427	G	79.5	Confident	81.5	Confident	25 Å²	25	28.6 Å²	28.6	26%	0.258	17%	0.165	S	C	.	.	H	α-helix	trans	-58	-46.3	175.4	0	0	0	0	0	112.3	S423 I424 A425 S430	S423-G427 PolarHBondContact O-N 3.1Å; I424-G427 CarbonylContact O-C 3.58Å; I424-G427 PolarHBondContact O-N 3.41Å; A425-G427 VanDerWaalsContact C-N 3.27Å; A425-G427 PolarHBondContact O-N 3.18Å; G427-S430 PolarHBondContact O-N 3.36Å; G427-S430 PolarHBondContact O-OG 3.11Å
428	F	85.2	Confident	81.3	Confident	35 Å²	35	29.2 Å²	29.2	15%	0.154	17%	0.171	C	C	.	.	H	α-helix	trans	-64.1	-47.3	175.6	-177.7	-103.4	0	0	0	112.1	F288 L291 F292 T301 I424 A425 P426 S430 I431 F432	F288-F428 HydrophobicContact CB-CD2 4.48Å; F288-F428 HydrophobicContact CD1-CB 3.84Å; F288-F428 AromaticContact CD1-CD2 3.94Å; F288-F428 HydrophobicContact CD1-CD2 3.94Å; F288-F428 HydrophobicContact CD1-CG 4.33Å; F288-F428 HydrophobicContact CE1-CB 3.91Å; F288-F428 HydrophobicContact CE1-CD2 4.47Å; F288-F428 HydrophobicContact CG-CD2 4.31Å; L291-F428 HydrophobicContact CD1-CB 3.58Å; L291-F428 HydrophobicContact CD1-CD1 4Å; L291-F428 HydrophobicContact CD1-CD2 4.31Å; L291-F428 HydrophobicContact CD1-CG 3.71Å; F292-F428 HydrophobicContact CE2-CE1 4.34Å; F292-F428 HydrophobicContact CE2-CE2 4.42Å; F292-F428 AromaticContact CE2-CZ 3.93Å; F292-F428 HydrophobicContact CE2-CZ 3.93Å; F292-F428 HydrophobicContact CZ-CE1 4.13Å; F292-F428 AromaticContact CZ-CZ 3.89Å; F292-F428 HydrophobicContact CZ-CZ 3.89Å; T301-F428 HydrophobicContact CG2-CD1 3.73Å; T301-F428 HydrophobicContact CG2-CE1 3.67Å; I424-F428 PolarHBondContact O-N 3.09Å; A425-F428 PolarHBondContact O-N 3.24Å; P426-F428 PolarHBondContact O-N 3.45Å; F428-S430 PolarHBondContact O-N 3.46Å; F428-I431 WeakPolarHBondContact O-CB 3.41Å; F428-I431 PolarHBondContact O-N 3.29Å; F428-F432 HydrophobicContact CD1-CE2 4.12Å; F428-F432 HydrophobicContact CE1-CD2 4.38Å; F428-F432 AromaticContact CE1-CE2 3.53Å; F428-F432 HydrophobicContact CE1-CE2 3.53Å; F428-F432 HydrophobicContact CE1-CZ 4.3Å; F428-F432 HydrophobicContact CE2-CE2 4.32Å; F428-F432 AromaticContact CZ-CE2 3.65Å; F428-F432 HydrophobicContact CZ-CE2 3.65Å; F428-F432 HydrophobicContact CZ-CZ 4.17Å
429	M	87.7	Confident	81.4	Confident	1 Å²	1	32.9 Å²	32.9	1%	0.005	19%	0.189	C	C	.	.	H	α-helix	trans	-63.4	-30.7	179.1	-66.7	172.2	-165.6	0	0	112.3	M304 M308 V413 Y417 A425 P426 I431 F432 I433	M304-M429 HydrophobicContact CB-CE 3.38Å; M304-M429 HydrophobicContact CB-SD 3.83Å; M304-M429 HydrophobicContact CG-CE 4.14Å; M308-M429 HydrophobicContact CE-SD 4.16Å; M308-M429 HydrophobicContact CG-CB 4.29Å; M308-M429 HydrophobicContact CG-SD 4.3Å; V413-M429 HydrophobicContact CB-SD 4.4Å; V413-M429 HydrophobicContact CG1-CE 4.02Å; V413-M429 HydrophobicContact CG1-SD 3.86Å; V413-M429 HydrophobicContact CG2-CE 4.17Å; V413-M429 HydrophobicContact CG2-SD 3.53Å; V413-M429 VanDerWaalsContact CG2-SD 3.53Å; Y417-M429 HydrophobicContact CE2-CE 3.68Å; Y417-M429 VanDerWaalsContact OH-CE 3.25Å; Y417-M429 WeakPolarHBondContact OH-CE 3.26Å; A425-M429 HydrophobicContact CB-CE 4.32Å; A425-M429 VanDerWaalsContact O-CG 3.29Å; A425-M429 WeakPolarHBondContact O-CG 3.23Å; A425-M429 PolarHBondContact O-N 3.29Å; P426-M429 PolarHBondContact O-N 3.1Å; M429-I431 PolarHBondContact O-N 3.26Å; M429-F432 WeakPolarHBondContact O-CB 3.39Å; M429-F432 PolarHBondContact O-N 3.39Å; M429-I433 WeakPolarHBondContact O-CG1 3.44Å; M429-I433 PolarHBondContact O-N 2.86Å
430	S	83.9	Confident	81.7	Confident	10 Å²	10	29.8 Å²	29.8	7%	0.07	17%	0.17	C	C	.	.	H	α-helix	trans	-60.3	-31	178.5	77.1	0	0	0	0	112.9	T124 P426 G427 F428 F432 I433 R434	T124-S430 VanDerWaalsContact CG2-OG 3.28Å; T124-S430 WeakPolarHBondContact CG2-OG 3.36Å; P426-S430 WeakPolarHBondContact O-CB 3.11Å; P426-S430 PolarHBondContact O-N 3.11Å; G427-S430 PolarHBondContact O-N 3.36Å; G427-S430 PolarHBondContact O-OG 3.11Å; F428-S430 PolarHBondContact O-N 3.46Å; S430-F432 VanDerWaalsContact C-N 3.31Å; S430-F432 PolarHBondContact O-N 3.3Å; S430-I433 PolarHBondContact O-N 3.11Å; S430-R434 WeakPolarHBondContact O-CG 3.14Å; S430-R434 PolarHBondContact O-N 3.39Å
431	I	85.9	Confident	82.2	Confident	57 Å²	57	29.6 Å²	29.6	29%	0.292	17%	0.169	S	C	.	.	H	α-helix	trans	-58.5	-45.9	174	-58.9	174.3	0	0	0	109.8	L121 F428 M429 R434 A435	L121-I431 HydrophobicContact CD1-CB 4.44Å; L121-I431 HydrophobicContact CD1-CG2 3.75Å; L121-I431 WeakPolarHBondContact CD1-O 3.21Å; F428-I431 WeakPolarHBondContact O-CB 3.41Å; F428-I431 PolarHBondContact O-N 3.29Å; M429-I431 PolarHBondContact O-N 3.26Å; I431-R434 PolarHBondContact O-N 3.34Å; I431-A435 WeakPolarHBondContact O-CB 3.35Å; I431-A435 PolarHBondContact O-N 3.12Å
432	F	89.7	Confident	82.7	Confident	77 Å²	77	33.3 Å²	33.3	34%	0.338	19%	0.186	S	C	.	.	H	α-helix	trans	-70.5	-38.5	178.4	-67	-87.6	0	0	0	112.5	F309 F428 M429 S430 R434 A435 A436	F309-F432 HydrophobicContact CB-CB 4.25Å; F309-F432 HydrophobicContact CD2-CB 4.38Å; F309-F432 VanDerWaalsContact CD2-O 3.3Å; F309-F432 WeakPolarHBondContact CD2-O 2.93Å; F428-F432 HydrophobicContact CD1-CE2 4.12Å; F428-F432 HydrophobicContact CE1-CD2 4.38Å; F428-F432 AromaticContact CE1-CE2 3.53Å; F428-F432 HydrophobicContact CE1-CE2 3.53Å; F428-F432 HydrophobicContact CE1-CZ 4.3Å; F428-F432 HydrophobicContact CE2-CE2 4.32Å; F428-F432 AromaticContact CZ-CE2 3.65Å; F428-F432 HydrophobicContact CZ-CE2 3.65Å; F428-F432 HydrophobicContact CZ-CZ 4.17Å; M429-F432 WeakPolarHBondContact O-CB 3.39Å; M429-F432 PolarHBondContact O-N 3.39Å; S430-F432 VanDerWaalsContact C-N 3.31Å; S430-F432 PolarHBondContact O-N 3.3Å; F432-R434 VanDerWaalsContact C-N 3.27Å; F432-R434 PolarHBondContact O-N 2.93Å; F432-A435 PolarHBondContact O-N 2.7Å; F432-A436 WeakPolarHBondContact O-CB 3.1Å; F432-A436 PolarHBondContact O-N 3.48Å
433	I	90.1	Very high	83.3	Confident	28 Å²	28	31.2 Å²	31.2	14%	0.144	18%	0.179	C	C	.	.	H	α-helix	trans	-56.8	-45.5	172.8	-64.7	174.5	0	0	0	110	M308 S312 W406 M429 S430 A436 S437	M308-I433 HydrophobicContact CB-CD1 4.19Å; M308-I433 HydrophobicContact CB-CG1 3.78Å; M308-I433 HydrophobicContact CG-CD1 4.46Å; M308-I433 HydrophobicContact SD-CD1 3.99Å; S312-I433 PolarHBondContact OG-O 3.22Å; W406-I433 HydrophobicContact CH2-CD1 3.59Å; W406-I433 HydrophobicContact CH2-CG1 3.92Å; W406-I433 HydrophobicContact CH2-CG2 4.37Å; W406-I433 HydrophobicContact CZ3-CD1 3.94Å; M429-I433 WeakPolarHBondContact O-CG1 3.44Å; M429-I433 PolarHBondContact O-N 2.86Å; S430-I433 PolarHBondContact O-N 3.11Å; I433-A436 PolarHBondContact O-N 3.46Å; I433-S437 PolarHBondContact O-N 2.86Å; I433-S437 PolarHBondContact O-OG 3.2Å; I433-S437 VanDerWaalsContact O-OG 3.1Å
434	R	86.5	Confident	83.9	Confident	34 Å²	34	28.2 Å²	28.2	13%	0.128	16%	0.156	C	C	.	.	H	α-helix	trans	-70.8	-39.6	-179.3	-61.9	-22.5	-173.4	168.7	-1.3	112.1	L120 L121 S430 I431 F432 A436 S437 G438	L120-R434 HydrophobicContact CD2-CG 4.31Å; L120-R434 HydrophobicContact CG-CG 4.13Å; L121-R434 HydrophobicContact CB-CB 3.96Å; L121-R434 HydrophobicContact CD1-CB 3.85Å; S430-R434 WeakPolarHBondContact O-CG 3.14Å; S430-R434 PolarHBondContact O-N 3.39Å; I431-R434 PolarHBondContact O-N 3.34Å; F432-R434 VanDerWaalsContact C-N 3.27Å; F432-R434 PolarHBondContact O-N 2.93Å; R434-A436 VanDerWaalsContact C-N 3.31Å; R434-A436 PolarHBondContact O-N 2.93Å; R434-S437 PolarHBondContact O-N 3.03Å; R434-G438 PolarHBondContact O-N 3.36Å
435	A	87.1	Confident	84.2	Confident	36 Å²	36	33.2 Å²	33.2	30%	0.298	17%	0.174	S	C	.	.	H	α-helix	trans	-58.7	-43.6	173.7	0	0	0	0	0	111.4	F309 I431 F432 G438 M439	F309-A435 HydrophobicContact CE2-CB 4.32Å; I431-A435 WeakPolarHBondContact O-CB 3.35Å; I431-A435 PolarHBondContact O-N 3.12Å; F432-A435 PolarHBondContact O-N 2.7Å; A435-G438 PolarHBondContact O-N 3.16Å; A435-M439 PolarHBondContact O-N 2.87Å
436	A	90.5	Very high	84.4	Confident	0 Å²	0	35.5 Å²	35.5	0%	0	19%	0.186	C	C	.	.	H	α-helix	trans	-64.8	-44.6	175.5	0	0	0	0	0	113.2	F309 F432 I433 R434 G438 M439	F309-A436 HydrophobicContact CB-CB 4.46Å; F309-A436 HydrophobicContact CD1-CB 4.24Å; F309-A436 HydrophobicContact CD2-CB 3.58Å; F309-A436 HydrophobicContact CE1-CB 4.38Å; F309-A436 HydrophobicContact CE2-CB 3.74Å; F309-A436 HydrophobicContact CG-CB 3.84Å; F309-A436 HydrophobicContact CZ-CB 4.15Å; F309-A436 WeakPolarHBondContact O-CB 3.41Å; F432-A436 WeakPolarHBondContact O-CB 3.1Å; F432-A436 PolarHBondContact O-N 3.48Å; I433-A436 PolarHBondContact O-N 3.46Å; R434-A436 VanDerWaalsContact C-N 3.31Å; R434-A436 PolarHBondContact O-N 2.93Å; A436-G438 PolarHBondContact O-N 2.85Å; A436-M439 WeakPolarHBondContact O-CB 3.39Å; A436-M439 PolarHBondContact O-N 3.28Å
437	S	82.7	Confident	84.6	Confident	3 Å²	3	34.4 Å²	34.4	2%	0.021	18%	0.181	C	C	.	.	H	α-helix	trans	-61.2	-34.2	174.6	-54.6	0	0	0	0	111.5	S312 I433 R434 M439 A440	S312-S437 PolarHBondContact OG-OG 3.35Å; I433-S437 PolarHBondContact O-N 2.86Å; I433-S437 PolarHBondContact O-OG 3.2Å; I433-S437 VanDerWaalsContact O-OG 3.1Å; R434-S437 PolarHBondContact O-N 3.03Å; S437-M439 PolarHBondContact O-N 2.84Å; S437-A440 WeakPolarHBondContact O-CB 3.28Å; S437-A440 PolarHBondContact O-N 3.22Å
438	G	79.5	Confident	84.7	Confident	13 Å²	13	38.3 Å²	38.3	13%	0.134	19%	0.188	C	C	.	.	T	Hydrogen-bonded Turn	trans	-69.1	-15.1	174	0	0	0	0	0	115.3	R434 A435 A436 Q442	R434-G438 PolarHBondContact O-N 3.36Å; A435-G438 PolarHBondContact O-N 3.16Å; A436-G438 PolarHBondContact O-N 2.85Å; G438-Q442 PolarHBondContact O-NE2 3.32Å; G438-Q442 PolarHBondContact O-OE1 3.45Å
439	M	79.6	Confident	84.7	Confident	77 Å²	77	41.8 Å²	41.8	38%	0.379	21%	0.212	S	C	.	.	T	Hydrogen-bonded Turn	trans	-86.9	-11.5	172.8	-72.7	-178.7	61.3	0	0	113.4	F309 A435 A436 S437 Q442 L443	F309-M439 HydrophobicContact CE1-SD 4.48Å; F309-M439 HydrophobicContact CE2-SD 4.13Å; F309-M439 HydrophobicContact CZ-SD 3.48Å; F309-M439 WeakPolarHBondContact CZ-SD 3.21Å; A435-M439 PolarHBondContact O-N 2.87Å; A436-M439 WeakPolarHBondContact O-CB 3.39Å; A436-M439 PolarHBondContact O-N 3.28Å; S437-M439 PolarHBondContact O-N 2.84Å; M439-Q442 WeakPolarHBondContact O-CB 3.27Å; M439-Q442 PolarHBondContact O-N 2.96Å; M439-Q442 VanDerWaalsContact O-N 3.15Å; M439-Q442 PolarHBondContact O-OE1 2.81Å; M439-Q442 VanDerWaalsContact O-OE1 3.12Å; M439-L443 PolarHBondContact O-N 3.17Å
440	A	79	Confident	84.8	Confident	2 Å²	2	46.8 Å²	46.8	2%	0.017	23%	0.231	C	C	.	.	H	α-helix	trans	-58.7	-43.2	-178.3	0	0	0	0	0	113.4	T316 Y320 S437 Q442 L443 L444	T316-A440 HydrophobicContact CG2-CB 3.28Å; Y320-A440 HydrophobicContact CD2-CB 4.13Å; Y320-A440 HydrophobicContact CE2-CB 4.14Å; S437-A440 WeakPolarHBondContact O-CB 3.28Å; S437-A440 PolarHBondContact O-N 3.22Å; A440-Q442 VanDerWaalsContact C-N 3.25Å; A440-Q442 PolarHBondContact O-N 2.83Å; A440-L443 PolarHBondContact O-N 2.91Å; A440-L444 WeakPolarHBondContact O-CG 3.13Å; A440-L444 PolarHBondContact O-N 3.44Å
441	P	77.7	Confident	85	Confident	3 Å²	3	53.3 Å²	53.3	2%	0.019	26%	0.258	C	S	.	.	H	α-helix	trans	-60.9	-33.9	176.3	-23.2	35.7	0	0	0	113.3	Y110 M113 L444 Y445	Y110-P441 HydrophobicContact CD1-CB 4.34Å; Y110-P441 WeakPolarHBondContact O-CB 3.39Å; M113-P441 HydrophobicContact CB-CB 4.1Å; M113-P441 HydrophobicContact CB-CG 3.41Å; M113-P441 VanDerWaalsContact CB-CG 3.41Å; M113-P441 HydrophobicContact CE-CG 4.29Å; M113-P441 HydrophobicContact CG-CG 4.48Å; M113-P441 HydrophobicContact SD-CG 4.44Å; P441-L444 PolarHBondContact O-N 3.18Å; P441-Y445 WeakPolarHBondContact O-CB 3.46Å; P441-Y445 PolarHBondContact O-N 3.38Å
442	Q	85.2	Confident	85.3	Confident	86 Å²	86	51.1 Å²	51.1	40%	0.402	25%	0.247	S	C	.	.	H	α-helix	trans	-73.6	-36.9	178.9	-64.4	75	3.2	0	0	110.5	T114 G438 M439 A440 Y445 L446	T114-Q442 PolarHBondContact OG1-NE2 3.06Å; G438-Q442 PolarHBondContact O-NE2 3.32Å; G438-Q442 PolarHBondContact O-OE1 3.45Å; M439-Q442 WeakPolarHBondContact O-CB 3.27Å; M439-Q442 PolarHBondContact O-N 2.96Å; M439-Q442 VanDerWaalsContact O-N 3.15Å; M439-Q442 PolarHBondContact O-OE1 2.81Å; M439-Q442 VanDerWaalsContact O-OE1 3.12Å; A440-Q442 VanDerWaalsContact C-N 3.25Å; A440-Q442 PolarHBondContact O-N 2.83Å; Q442-Y445 PolarHBondContact O-N 3.05Å; Q442-L446 VanDerWaalsContact O-CB 3.29Å; Q442-L446 WeakPolarHBondContact O-CB 3.42Å; Q442-L446 PolarHBondContact O-N 3.18Å
443	L	86.5	Confident	85.5	Confident	6 Å²	6	47.4 Å²	47.4	3%	0.031	23%	0.231	C	C	.	.	H	α-helix	trans	-64.3	-43.7	170.2	-66.3	178.3	0	0	0	110.7	T317 M439 A440 Y445 L446 A447 P454 I457	T317-L443 WeakPolarHBondContact OG1-CD1 3.47Å; M439-L443 PolarHBondContact O-N 3.17Å; A440-L443 PolarHBondContact O-N 2.91Å; L443-Y445 VanDerWaalsContact C-N 3.32Å; L443-Y445 PolarHBondContact O-N 3.38Å; L443-L446 WeakPolarHBondContact O-CB 3.4Å; L443-L446 PolarHBondContact O-N 3.27Å; L443-A447 PolarHBondContact O-N 2.7Å; L443-P454 HydrophobicContact CB-CB 4.31Å; L443-P454 WeakPolarHBondContact O-CG 3.36Å; L443-I457 HydrophobicContact CD2-CB 4.2Å; L443-I457 HydrophobicContact CD2-CD1 3.52Å; L443-I457 HydrophobicContact CD2-CG1 4.46Å; L443-I457 HydrophobicContact CD2-CG2 4.12Å
444	L	82.7	Confident	85.7	Confident	26 Å²	26	46.4 Å²	46.4	14%	0.136	23%	0.226	C	C	.	.	H	α-helix	trans	-63.2	-38.2	175.7	-65.5	173.1	0	0	0	112.6	Y110 M113 Y320 A440 P441 A447	Y110-L444 HydrophobicContact CD1-CB 4.14Å; Y110-L444 HydrophobicContact CE1-CB 3.6Å; Y110-L444 HydrophobicContact CE1-CD1 4.3Å; M113-L444 HydrophobicContact CE-CD1 3.83Å; M113-L444 HydrophobicContact SD-CD1 4.35Å; Y320-L444 HydrophobicContact CD2-CD1 4.17Å; Y320-L444 HydrophobicContact CG-CD1 3.95Å; A440-L444 WeakPolarHBondContact O-CG 3.13Å; A440-L444 PolarHBondContact O-N 3.44Å; P441-L444 PolarHBondContact O-N 3.18Å; L444-A447 WeakPolarHBondContact O-CB 3.4Å; L444-A447 PolarHBondContact O-N 3.48Å
445	Y	84.3	Confident	86	Confident	131 Å²	131	46 Å²	46	51%	0.514	23%	0.225	S	C	.	.	H	α-helix	trans	-65.2	-44.3	172.4	179.5	-100.6	0	0	0	111.5	Y110 P441 Q442 L443 A447 R448 V449	Y110-Y445 HydrophobicContact CD2-CD2 4.25Å; Y110-Y445 HydrophobicContact CE2-CD2 4.31Å; P441-Y445 WeakPolarHBondContact O-CB 3.46Å; P441-Y445 PolarHBondContact O-N 3.38Å; Q442-Y445 PolarHBondContact O-N 3.05Å; L443-Y445 VanDerWaalsContact C-N 3.32Å; L443-Y445 PolarHBondContact O-N 3.38Å; Y445-A447 PolarHBondContact O-N 3.38Å; Y445-R448 WeakPolarHBondContact O-CB 3.31Å; Y445-R448 PolarHBondContact O-N 3.42Å; Y445-V449 HydrophobicContact CE1-CG2 4.23Å
446	L	87.6	Confident	86.5	Confident	47 Å²	47	47.9 Å²	47.9	25%	0.246	23%	0.226	C	C	.	.	H	α-helix	trans	-58.6	-37.1	175.7	-177.6	66	0	0	0	111.4	Q442 L443 R448 V449 W450 I457	Q442-L446 VanDerWaalsContact O-CB 3.29Å; Q442-L446 WeakPolarHBondContact O-CB 3.42Å; Q442-L446 PolarHBondContact O-N 3.18Å; L443-L446 WeakPolarHBondContact O-CB 3.4Å; L443-L446 PolarHBondContact O-N 3.27Å; L446-R448 PolarHBondContact O-N 2.95Å; L446-V449 PolarHBondContact O-N 3.38Å; L446-V449 VanDerWaalsContact O-N 3.12Å; L446-W450 HydrophobicContact CD1-CB 4.29Å; L446-W450 HydrophobicContact CD1-CE3 4.45Å; L446-W450 HydrophobicContact CD2-CE3 4.44Å; L446-W450 CarbonylContact O-C 3.53Å; L446-W450 WeakPolarHBondContact O-CA 3.22Å; L446-W450 PolarHBondContact O-N 2.91Å; L446-W450 VanDerWaalsContact O-O 3.12Å; L446-I457 HydrophobicContact CD2-CD1 3.43Å; L446-I457 VanDerWaalsContact CD2-CD1 3.43Å
447	A	86.2	Confident	86.7	Confident	26 Å²	26	50.2 Å²	50.2	22%	0.215	24%	0.238	C	C	.	.	H	α-helix	trans	-57	-29.7	176.4	0	0	0	0	0	113.3	L443 L444 Y445 K451 P454	L443-A447 PolarHBondContact O-N 2.7Å; L444-A447 WeakPolarHBondContact O-CB 3.4Å; L444-A447 PolarHBondContact O-N 3.48Å; Y445-A447 PolarHBondContact O-N 3.38Å; A447-K451 VanDerWaalsContact O-CA 3.27Å; A447-K451 WeakPolarHBondContact O-CA 3.27Å; A447-K451 PolarHBondContact O-N 2.83Å; A447-P454 HydrophobicContact CB-CG 3.54Å
448	R	80.3	Confident	87.3	Confident	107 Å²	107	50.1 Å²	50.1	40%	0.404	24%	0.237	S	C	.	.	H	α-helix	trans	-75.3	-38.4	177.3	-67.3	-170.5	172.5	-145.4	-6.1	112.7	E52 Y110 Y445 L446	E52-R448 IonicContact OE2-CZ 3.99Å; E52-R448 IonicContact OE2-NH1 2.66Å; E52-R448 IonicContact OE2-NH2 3.04Å; E52-R448 PolarHBondContact OE2-NH2 2.7Å; Y110-R448 PolarHBondContact OH-NE 3.31Å; Y445-R448 WeakPolarHBondContact O-CB 3.31Å; Y445-R448 PolarHBondContact O-N 3.42Å; L446-R448 PolarHBondContact O-N 2.95Å
449	V	85.7	Confident	88.2	Confident	108 Å²	108	51.3 Å²	51.3	66%	0.655	24%	0.24	S	C	*	.	H	α-helix	trans	-82.2	-38.3	-179.2	-177.4	0	0	0	0	110.8	Y445 L446	Y445-V449 HydrophobicContact CE1-CG2 4.23Å; L446-V449 PolarHBondContact O-N 3.38Å; L446-V449 VanDerWaalsContact O-N 3.12Å
450	W	89.6	Confident	89	Confident	106 Å²	106	51.4 Å²	51.4	40%	0.402	24%	0.241	S	C	.	.	S	Bend	trans	-143.3	92.1	-177.6	-173	45.6	0	0	0	109.9	L446 P452 G453 F456	L446-W450 HydrophobicContact CD1-CB 4.29Å; L446-W450 HydrophobicContact CD1-CE3 4.45Å; L446-W450 HydrophobicContact CD2-CE3 4.44Å; L446-W450 CarbonylContact O-C 3.53Å; L446-W450 WeakPolarHBondContact O-CA 3.22Å; L446-W450 PolarHBondContact O-N 2.91Å; L446-W450 VanDerWaalsContact O-O 3.12Å; W450-P452 VanDerWaalsContact C-CD 3.49Å; W450-P452 HydrophobicContact CD2-CG 4.21Å; W450-P452 HydrophobicContact CG-CG 4.28Å; W450-P452 HydrophobicContact CZ2-CG 4.06Å; W450-P452 VanDerWaalsContact NE1-CG 3.32Å; W450-G453 WeakPolarHBondContact O-CA 3.44Å; W450-G453 PolarHBondContact O-N 3.48Å; W450-F456 HydrophobicContact CH2-CB 4.19Å; W450-F456 AromaticContact CH2-CD1 3.62Å; W450-F456 HydrophobicContact CH2-CD1 3.62Å; W450-F456 HydrophobicContact CH2-CE1 4.16Å; W450-F456 AromaticContact CH2-CG 3.96Å; W450-F456 HydrophobicContact CH2-CG 3.96Å; W450-F456 HydrophobicContact CZ3-CD1 4.06Å
451	K	88.1	Confident	89.9	Confident	147 Å²	147	52.7 Å²	52.7	64%	0.639	25%	0.248	S	C	*	.	T	Hydrogen-bonded Turn	trans	-45.4	-47.1	-176.9	-65.6	-174.7	179.9	-178.6	0	115.6	A447 G453 P454	A447-K451 VanDerWaalsContact O-CA 3.27Å; A447-K451 WeakPolarHBondContact O-CA 3.27Å; A447-K451 PolarHBondContact O-N 2.83Å; K451-G453 PolarHBondContact O-N 3.16Å; K451-P454 WeakPolarHBondContact O-CD 3.46Å
452	P	92.8	Very high	90.8	Very high	10 Å²	10	52.6 Å²	52.6	7%	0.065	25%	0.247	C	C	.	.	T	Hydrogen-bonded Turn	trans	-75	-9.7	179.4	30.3	-36.4	0	0	0	113.8	E381 F382 W450 W455 F456	E381-P452 HydrophobicContact CB-CB 3.78Å; F382-P452 HydrophobicContact CD2-CG 4.38Å; W450-P452 VanDerWaalsContact C-CD 3.49Å; W450-P452 HydrophobicContact CD2-CG 4.21Å; W450-P452 HydrophobicContact CG-CG 4.28Å; W450-P452 HydrophobicContact CZ2-CG 4.06Å; W450-P452 VanDerWaalsContact NE1-CG 3.32Å; P452-W455 PolarHBondContact O-N 3.02Å; P452-F456 WeakPolarHBondContact O-CB 3.32Å; P452-F456 PolarHBondContact O-N 2.89Å
453	G	93.6	Very high	91.4	Very high	0 Å²	0	50.4 Å²	50.4	0%	0	24%	0.243	C	C	.	.	H	α-helix	trans	-54.7	-49.3	-171.1	0	0	0	0	0	116.1	W450 K451 W455 F456 I457	W450-G453 WeakPolarHBondContact O-CA 3.44Å; W450-G453 PolarHBondContact O-N 3.48Å; K451-G453 PolarHBondContact O-N 3.16Å; G453-W455 VanDerWaalsContact C-N 3.33Å; G453-W455 PolarHBondContact O-N 3.47Å; G453-F456 PolarHBondContact O-N 2.84Å; G453-I457 WeakPolarHBondContact O-CG1 3.38Å; G453-I457 PolarHBondContact O-N 3.28Å
454	P	93.3	Very high	92	Very high	7 Å²	7	53.2 Å²	53.2	5%	0.045	26%	0.263	C	S	.	.	H	α-helix	trans	-61	-42.1	178.8	-20.8	30.8	0	0	0	112.8	T317 L443 A447 K451 N458	T317-P454 HydrophobicContact CG2-CB 4.05Å; L443-P454 HydrophobicContact CB-CB 4.31Å; L443-P454 WeakPolarHBondContact O-CG 3.36Å; A447-P454 HydrophobicContact CB-CG 3.54Å; K451-P454 WeakPolarHBondContact O-CD 3.46Å; P454-N458 WeakPolarHBondContact O-CB 3.45Å; P454-N458 PolarHBondContact O-N 3.42Å; P454-N458 VanDerWaalsContact O-N 3.11Å; P454-N458 PolarHBondContact O-ND2 2.65Å
455	W	94.7	Very high	92.7	Very high	25 Å²	25	52.2 Å²	52.2	10%	0.095	26%	0.257	C	S	.	.	H	α-helix	trans	-69.1	-42	-179.6	-52.4	119.8	0	0	0	111	T317 L318 L377 T378 V395 P452 G453 N458 M459	T317-W455 HydrophobicContact CG2-CZ3 4.34Å; L318-W455 HydrophobicContact CD2-CZ3 3.98Å; L377-W455 HydrophobicContact CB-CB 4.15Å; L377-W455 HydrophobicContact CB-CD2 3.96Å; L377-W455 HydrophobicContact CB-CE3 4.24Å; L377-W455 HydrophobicContact CB-CG 3.93Å; L377-W455 HydrophobicContact CD1-CD2 4.14Å; L377-W455 HydrophobicContact CD1-CE3 3.65Å; L377-W455 HydrophobicContact CD1-CH2 4.22Å; L377-W455 HydrophobicContact CD1-CZ3 3.7Å; L377-W455 HydrophobicContact CG-CE3 4.5Å; T378-W455 WeakPolarHBondContact OG1-CB 3.32Å; T378-W455 PolarHBondContact OG1-O 3.11Å; V395-W455 HydrophobicContact CG2-CH2 4.09Å; P452-W455 PolarHBondContact O-N 3.02Å; G453-W455 VanDerWaalsContact C-N 3.33Å; G453-W455 PolarHBondContact O-N 3.47Å; W455-N458 PolarHBondContact O-N 3.05Å; W455-M459 VanDerWaalsContact O-CB 3.29Å; W455-M459 WeakPolarHBondContact O-CB 3.27Å; W455-M459 PolarHBondContact O-N 2.9Å
456	F	96	Very high	93.3	Very high	75 Å²	75	47.3 Å²	47.3	33%	0.329	24%	0.24	S	C	.	.	H	α-helix	trans	-63.1	-44.5	177.5	-177.5	-104.3	0	0	0	112.3	T378 W450 P452 G453 M459 I460	T378-F456 HydrophobicContact CG2-CB 3.96Å; T378-F456 HydrophobicContact CG2-CD2 3.92Å; T378-F456 HydrophobicContact CG2-CG 4.45Å; T378-F456 PolarHBondContact OG1-N 3.31Å; W450-F456 HydrophobicContact CH2-CB 4.19Å; W450-F456 AromaticContact CH2-CD1 3.62Å; W450-F456 HydrophobicContact CH2-CD1 3.62Å; W450-F456 HydrophobicContact CH2-CE1 4.16Å; W450-F456 AromaticContact CH2-CG 3.96Å; W450-F456 HydrophobicContact CH2-CG 3.96Å; W450-F456 HydrophobicContact CZ3-CD1 4.06Å; P452-F456 WeakPolarHBondContact O-CB 3.32Å; P452-F456 PolarHBondContact O-N 2.89Å; G453-F456 PolarHBondContact O-N 2.84Å; F456-M459 HydrophobicContact CD2-CE 3.48Å; F456-M459 VanDerWaalsContact CD2-CE 3.48Å; F456-M459 HydrophobicContact CE2-CE 3.56Å; F456-M459 HydrophobicContact CG-CE 4.42Å; F456-M459 WeakPolarHBondContact O-CB 3.42Å; F456-M459 PolarHBondContact O-N 3.16Å; F456-I460 HydrophobicContact CD1-CD1 3.92Å; F456-I460 HydrophobicContact CE1-CD1 3.44Å; F456-I460 VanDerWaalsContact CE1-CD1 3.44Å; F456-I460 HydrophobicContact CE2-CD1 4.42Å; F456-I460 HydrophobicContact CZ-CD1 3.73Å; F456-I460 WeakPolarHBondContact O-CG1 3.28Å; F456-I460 PolarHBondContact O-N 3.29Å
457	I	96	Very high	93.8	Very high	50 Å²	50	50.3 Å²	50.3	26%	0.256	26%	0.256	S	S	.	.	H	α-helix	trans	-63.6	-46.6	176.9	-69.8	168.9	0	0	0	110.6	L443 L446 G453 M459 I460 L461	L443-I457 HydrophobicContact CD2-CB 4.2Å; L443-I457 HydrophobicContact CD2-CD1 3.52Å; L443-I457 HydrophobicContact CD2-CG1 4.46Å; L443-I457 HydrophobicContact CD2-CG2 4.12Å; L446-I457 HydrophobicContact CD2-CD1 3.43Å; L446-I457 VanDerWaalsContact CD2-CD1 3.43Å; G453-I457 WeakPolarHBondContact O-CG1 3.38Å; G453-I457 PolarHBondContact O-N 3.28Å; I457-M459 VanDerWaalsContact C-N 3.3Å; I457-M459 PolarHBondContact O-N 3.16Å; I457-I460 PolarHBondContact O-N 3.47Å; I457-L461 HydrophobicContact CG2-CD1 3.97Å; I457-L461 HydrophobicContact CG2-CG 4.36Å; I457-L461 WeakPolarHBondContact O-CG 3.32Å; I457-L461 PolarHBondContact O-N 3.43Å
458	N	95.8	Very high	94.2	Very high	0 Å²	0	50 Å²	50	0%	0	26%	0.255	C	S	.	.	H	α-helix	trans	-68	-29.1	178.7	-76.5	-41.2	0	0	0	112.9	S313 I314 T317 H374 P454 W455 S462	S313-N458 PolarHBondContact OG-OD1 3.41Å; I314-N458 HydrophobicContact CG1-CB 3.92Å; T317-N458 WeakPolarHBondContact CB-ND2 3.09Å; T317-N458 WeakPolarHBondContact CG2-ND2 3.42Å; T317-N458 PolarHBondContact OG1-ND2 2.93Å; H374-N458 WeakPolarHBondContact CD2-CB 3.46Å; P454-N458 WeakPolarHBondContact O-CB 3.45Å; P454-N458 PolarHBondContact O-N 3.42Å; P454-N458 VanDerWaalsContact O-N 3.11Å; P454-N458 PolarHBondContact O-ND2 2.65Å; W455-N458 PolarHBondContact O-N 3.05Å; N458-S462 WeakPolarHBondContact O-CB 3.47Å; N458-S462 PolarHBondContact O-N 2.86Å; N458-S462 PolarHBondContact O-OG 2.68Å
459	M	97.1	Very high	95	Very high	39 Å²	39	45 Å²	45	19%	0.192	24%	0.236	C	C	.	.	H	α-helix	trans	-60.9	-49.3	168.9	178.9	-167	74.2	0	0	110.8	L371 H374 I375 W455 F456 I457 S462 A463	L371-M459 HydrophobicContact CD1-CG 3.98Å; L371-M459 WeakPolarHBondContact CD1-O 3.33Å; H374-M459 HydrophobicContact CB-CB 3.98Å; I375-M459 HydrophobicContact CB-SD 4.39Å; I375-M459 HydrophobicContact CG1-CG 3.71Å; I375-M459 HydrophobicContact CG1-SD 3.69Å; W455-M459 VanDerWaalsContact O-CB 3.29Å; W455-M459 WeakPolarHBondContact O-CB 3.27Å; W455-M459 PolarHBondContact O-N 2.9Å; F456-M459 HydrophobicContact CD2-CE 3.48Å; F456-M459 VanDerWaalsContact CD2-CE 3.48Å; F456-M459 HydrophobicContact CE2-CE 3.56Å; F456-M459 HydrophobicContact CG-CE 4.42Å; F456-M459 WeakPolarHBondContact O-CB 3.42Å; F456-M459 PolarHBondContact O-N 3.16Å; I457-M459 VanDerWaalsContact C-N 3.3Å; I457-M459 PolarHBondContact O-N 3.16Å; M459-S462 PolarHBondContact O-N 3.29Å; M459-S462 PolarHBondContact O-OG 3.33Å; M459-A463 PolarHBondContact O-N 2.91Å
460	I	97.5	Very high	95.4	Very high	78 Å²	78	42 Å²	42	40%	0.4	22%	0.218	S	C	.	.	H	α-helix	trans	-62.5	-45.9	177	-66	168.3	0	0	0	110.8	F456 I457 S462 A463 C464	F456-I460 HydrophobicContact CD1-CD1 3.92Å; F456-I460 HydrophobicContact CE1-CD1 3.44Å; F456-I460 VanDerWaalsContact CE1-CD1 3.44Å; F456-I460 HydrophobicContact CE2-CD1 4.42Å; F456-I460 HydrophobicContact CZ-CD1 3.73Å; F456-I460 WeakPolarHBondContact O-CG1 3.28Å; F456-I460 PolarHBondContact O-N 3.29Å; I457-I460 PolarHBondContact O-N 3.47Å; I460-S462 PolarHBondContact O-N 3.29Å; I460-A463 PolarHBondContact O-N 3.34Å; I460-C464 WeakPolarHBondContact O-CB 3.46Å; I460-C464 PolarHBondContact O-N 2.98Å; I460-C464 PolarHBondContact O-SG 3.36Å; I460-C464 VanDerWaalsContact O-SG 3.38Å
461	L	97	Very high	95.6	Very high	30 Å²	30	42.7 Å²	42.7	16%	0.157	23%	0.229	C	C	.	.	H	α-helix	trans	-61.4	-42.1	179	-71.6	175.9	0	0	0	112.2	F309 S310 I457 C464 F465	F309-L461 HydrophobicContact CD1-CD2 4.25Å; F309-L461 HydrophobicContact CE1-CD1 4.2Å; F309-L461 HydrophobicContact CE1-CD2 4.12Å; S310-L461 PolarHBondContact OG-O 3.35Å; I457-L461 HydrophobicContact CG2-CD1 3.97Å; I457-L461 HydrophobicContact CG2-CG 4.36Å; I457-L461 WeakPolarHBondContact O-CG 3.32Å; I457-L461 PolarHBondContact O-N 3.43Å; L461-C464 PolarHBondContact O-N 3.45Å; L461-F465 WeakPolarHBondContact O-CB 3.37Å; L461-F465 PolarHBondContact O-N 2.98Å
462	S	97.5	Very high	95.9	Very high	0 Å²	0	41.1 Å²	41.1	0%	0	22%	0.223	C	C	.	.	H	α-helix	trans	-67.9	-34.9	176.6	59.5	0	0	0	0	112.8	L371 N458 M459 I460 L466	L371-S462 WeakPolarHBondContact CD1-OG 3.44Å; N458-S462 WeakPolarHBondContact O-CB 3.47Å; N458-S462 PolarHBondContact O-N 2.86Å; N458-S462 PolarHBondContact O-OG 2.68Å; M459-S462 PolarHBondContact O-N 3.29Å; M459-S462 PolarHBondContact O-OG 3.33Å; I460-S462 PolarHBondContact O-N 3.29Å; S462-L466 WeakPolarHBondContact O-CB 3.49Å; S462-L466 PolarHBondContact O-N 3.22Å
463	A	98.1	Very high	95.9	Very high	40 Å²	40	40.8 Å²	40.8	33%	0.331	22%	0.22	S	C	.	.	H	α-helix	trans	-65.9	-46.1	172.3	0	0	0	0	0	112	L371 M459 I460 F465 L466 L467	L371-A463 HydrophobicContact CD1-CB 3.99Å; L371-A463 HydrophobicContact CD2-CB 4.36Å; M459-A463 PolarHBondContact O-N 2.91Å; I460-A463 PolarHBondContact O-N 3.34Å; A463-F465 PolarHBondContact O-N 2.9Å; A463-L466 PolarHBondContact O-N 3.31Å; A463-L467 WeakPolarHBondContact O-CB 3.38Å; A463-L467 PolarHBondContact O-N 3.49Å
464	C	97.6	Very high	95.8	Very high	65 Å²	65	42.9 Å²	42.9	44%	0.439	23%	0.234	S	C	.	.	H	α-helix	trans	-61.1	-43.5	175.8	-74.2	0	0	0	0	112	I460 L461 G468	I460-C464 WeakPolarHBondContact O-CB 3.46Å; I460-C464 PolarHBondContact O-N 2.98Å; I460-C464 PolarHBondContact O-SG 3.36Å; I460-C464 VanDerWaalsContact O-SG 3.38Å; L461-C464 PolarHBondContact O-N 3.45Å; C464-G468 PolarHBondContact O-N 2.68Å
465	F	97.7	Very high	95.6	Very high	5 Å²	5	44.8 Å²	44.8	2%	0.022	24%	0.242	C	C	.	.	H	α-helix	trans	-53.8	-60.3	170.5	-180	143.2	0	0	0	108.7	S307 L311 I363 T367 I405 I409 L461 A463 L467 G468 F469	S307-F465 VanDerWaalsContact CA-CD1 3.49Å; S307-F465 VanDerWaalsContact O-CD1 3.27Å; S307-F465 WeakPolarHBondContact O-CD1 3.46Å; S307-F465 WeakPolarHBondContact O-CE1 3.43Å; L311-F465 HydrophobicContact CB-CE1 4.27Å; I363-F465 HydrophobicContact CG2-CE2 3.63Å; I363-F465 HydrophobicContact CG2-CZ 3.73Å; T367-F465 HydrophobicContact CG2-CB 4.32Å; T367-F465 HydrophobicContact CG2-CD2 3.73Å; T367-F465 HydrophobicContact CG2-CE2 4.16Å; T367-F465 HydrophobicContact CG2-CG 3.97Å; I405-F465 HydrophobicContact CG2-CE1 4.08Å; I405-F465 HydrophobicContact CG2-CZ 3.83Å; I409-F465 HydrophobicContact CD1-CE1 3.66Å; I409-F465 HydrophobicContact CD1-CZ 3.43Å; I409-F465 VanDerWaalsContact CD1-CZ 3.43Å; I409-F465 HydrophobicContact CG1-CZ 4.34Å; L461-F465 WeakPolarHBondContact O-CB 3.37Å; L461-F465 PolarHBondContact O-N 2.98Å; A463-F465 PolarHBondContact O-N 2.9Å; F465-L467 VanDerWaalsContact C-N 3.31Å; F465-L467 PolarHBondContact O-N 2.86Å; F465-G468 PolarHBondContact O-N 2.95Å; F465-F469 HydrophobicContact CD2-CB 3.87Å; F465-F469 HydrophobicContact CD2-CG 4.44Å; F465-F469 HydrophobicContact CE2-CB 3.78Å; F465-F469 AromaticContact CE2-CD2 3.92Å; F465-F469 HydrophobicContact CE2-CD2 3.92Å; F465-F469 AromaticContact CE2-CG 3.86Å; F465-F469 HydrophobicContact CE2-CG 3.86Å; F465-F469 VanDerWaalsContact O-CB 3.29Å; F465-F469 WeakPolarHBondContact O-CB 3.38Å; F465-F469 PolarHBondContact O-N 3.35Å
466	L	97.7	Very high	95.2	Very high	28 Å²	28	44.1 Å²	44.1	15%	0.147	24%	0.241	C	C	.	.	H	α-helix	trans	-56	-47.6	-170.6	-177.2	63	0	0	0	110.9	V364 T367 F368 L371 S462 A463 T470	V364-L466 HydrophobicContact CB-CD1 4.43Å; V364-L466 HydrophobicContact CG1-CD1 3.91Å; T367-L466 HydrophobicContact CG2-CB 3.93Å; T367-L466 HydrophobicContact CG2-CD1 4.21Å; F368-L466 HydrophobicContact CB-CD2 4.33Å; F368-L466 HydrophobicContact CD2-CD2 4.09Å; L371-L466 HydrophobicContact CD2-CD2 3.95Å; S462-L466 WeakPolarHBondContact O-CB 3.49Å; S462-L466 PolarHBondContact O-N 3.22Å; A463-L466 PolarHBondContact O-N 3.31Å; L466-T470 HydrophobicContact CD1-CG2 4.08Å; L466-T470 VanDerWaalsContact O-CB 3.29Å; L466-T470 WeakPolarHBondContact O-CB 3.44Å; L466-T470 WeakPolarHBondContact O-CG2 3.37Å; L466-T470 PolarHBondContact O-N 3.06Å; L466-T470 PolarHBondContact O-OG1 3.29Å
467	L	97.5	Very high	94.3	Very high	110 Å²	110	42.4 Å²	42.4	58%	0.576	23%	0.233	S	C	*	.	H	α-helix	trans	-63.8	-49.3	178.8	-174.2	66.8	0	0	0	112.1	A463 F465 F469 T470 L471	A463-L467 WeakPolarHBondContact O-CB 3.38Å; A463-L467 PolarHBondContact O-N 3.49Å; F465-L467 VanDerWaalsContact C-N 3.31Å; F465-L467 PolarHBondContact O-N 2.86Å; L467-F469 PolarHBondContact O-N 3.33Å; L467-T470 PolarHBondContact O-OG1 3.32Å; L467-L471 HydrophobicContact CD1-CD1 3.62Å; L467-L471 HydrophobicContact CD1-CG 4.2Å; L467-L471 HydrophobicContact CG-CD1 3.91Å; L467-L471 WeakPolarHBondContact O-CB 3.3Å; L467-L471 VanDerWaalsContact O-CG 3.25Å; L467-L471 WeakPolarHBondContact O-CG 3.46Å; L467-L471 PolarHBondContact O-N 3.06Å; L467-L471 VanDerWaalsContact O-N 3.12Å
468	G	95.5	Very high	93.2	Very high	20 Å²	20	44.1 Å²	44.1	21%	0.206	26%	0.263	C	S	.	.	H	α-helix	trans	-61.7	-45.9	-179.8	0	0	0	0	0	112.2	V303 C464 F465 K472	V303-G468 WeakPolarHBondContact CG1-O 3.35Å; C464-G468 PolarHBondContact O-N 2.68Å; F465-G468 PolarHBondContact O-N 2.95Å; G468-K472 WeakPolarHBondContact O-CB 3.33Å; G468-K472 PolarHBondContact O-N 3.47Å
469	F	95.6	Very high	92.3	Very high	1 Å²	1	50 Å²	50	0%	0.004	29%	0.289	C	S	.	.	H	α-helix	trans	-68.3	-45.1	-177.5	-162.3	-84.8	0	0	0	111.9	M304 K360 I363 V364 V412 F465 L467 L471 I473	M304-F469 HydrophobicContact CE-CE2 4.38Å; M304-F469 HydrophobicContact SD-CD2 4.21Å; M304-F469 HydrophobicContact SD-CE2 3.78Å; K360-F469 HydrophobicContact CB-CE1 4.42Å; K360-F469 HydrophobicContact CG-CD1 4.48Å; K360-F469 HydrophobicContact CG-CE1 4.07Å; I363-F469 HydrophobicContact CB-CD1 4.49Å; I363-F469 HydrophobicContact CB-CE1 3.94Å; I363-F469 HydrophobicContact CB-CZ 4.2Å; I363-F469 HydrophobicContact CD1-CE1 3.97Å; I363-F469 HydrophobicContact CD1-CE2 4.15Å; I363-F469 HydrophobicContact CD1-CZ 3.42Å; I363-F469 VanDerWaalsContact CD1-CZ 3.42Å; I363-F469 HydrophobicContact CG1-CZ 4.4Å; I363-F469 HydrophobicContact CG2-CD1 3.83Å; I363-F469 HydrophobicContact CG2-CD2 4.32Å; I363-F469 HydrophobicContact CG2-CE1 3.65Å; I363-F469 HydrophobicContact CG2-CE2 4.16Å; I363-F469 HydrophobicContact CG2-CG 4.17Å; I363-F469 HydrophobicContact CG2-CZ 3.84Å; V364-F469 HydrophobicContact CG2-CD1 4.18Å; V412-F469 HydrophobicContact CG1-CZ 4.4Å; F465-F469 HydrophobicContact CD2-CB 3.87Å; F465-F469 HydrophobicContact CD2-CG 4.44Å; F465-F469 HydrophobicContact CE2-CB 3.78Å; F465-F469 AromaticContact CE2-CD2 3.92Å; F465-F469 HydrophobicContact CE2-CD2 3.92Å; F465-F469 AromaticContact CE2-CG 3.86Å; F465-F469 HydrophobicContact CE2-CG 3.86Å; F465-F469 VanDerWaalsContact O-CB 3.29Å; F465-F469 WeakPolarHBondContact O-CB 3.38Å; F465-F469 PolarHBondContact O-N 3.35Å; L467-F469 PolarHBondContact O-N 3.33Å; F469-L471 PolarHBondContact O-N 2.82Å; F469-I473 HydrophobicContact CD1-CB 4.3Å; F469-I473 HydrophobicContact CD2-CB 4.17Å; F469-I473 HydrophobicContact CD2-CG1 3.81Å; F469-I473 HydrophobicContact CD2-CG2 4.48Å; F469-I473 HydrophobicContact CE1-CB 4.24Å; F469-I473 HydrophobicContact CE1-CG2 4.16Å; F469-I473 HydrophobicContact CE2-CB 4.12Å; F469-I473 HydrophobicContact CE2-CG1 4.01Å; F469-I473 HydrophobicContact CE2-CG2 3.93Å; F469-I473 HydrophobicContact CG-CB 4.25Å; F469-I473 HydrophobicContact CG-CG1 4.18Å; F469-I473 HydrophobicContact CZ-CB 4.14Å; F469-I473 HydrophobicContact CZ-CG2 3.73Å; F469-I473 WeakPolarHBondContact O-CB 3.45Å; F469-I473 PolarHBondContact O-N 3.37Å; F469-I473 VanDerWaalsContact O-N 3.1Å
470	T	94.8	Very high	91.1	Very high	45 Å²	45	52.6 Å²	52.6	28%	0.276	32%	0.316	S	S	.	.	H	α-helix	trans	-62.1	-43	178.4	50.5	0	0	0	0	112.2	K360 V364 L466 L467	K360-T470 WeakPolarHBondContact CE-O 3.26Å; K360-T470 PolarHBondContact NZ-O 3.39Å; V364-T470 HydrophobicContact CB-CG2 4.32Å; V364-T470 HydrophobicContact CG1-CG2 3.77Å; V364-T470 HydrophobicContact CG2-CG2 3.52Å; L466-T470 HydrophobicContact CD1-CG2 4.08Å; L466-T470 VanDerWaalsContact O-CB 3.29Å; L466-T470 WeakPolarHBondContact O-CB 3.44Å; L466-T470 WeakPolarHBondContact O-CG2 3.37Å; L466-T470 PolarHBondContact O-N 3.06Å; L466-T470 PolarHBondContact O-OG1 3.29Å; L467-T470 PolarHBondContact O-OG1 3.32Å
471	L	94.5	Very high	89.6	Confident	122 Å²	122	52.3 Å²	52.3	64%	0.639	32%	0.315	S	S	*	.	H	α-helix	trans	-79.6	-38.2	-175.1	-66.8	178.8	0	0	0	113.8	L467 F469	L467-L471 HydrophobicContact CD1-CD1 3.62Å; L467-L471 HydrophobicContact CD1-CG 4.2Å; L467-L471 HydrophobicContact CG-CD1 3.91Å; L467-L471 WeakPolarHBondContact O-CB 3.3Å; L467-L471 VanDerWaalsContact O-CG 3.25Å; L467-L471 WeakPolarHBondContact O-CG 3.46Å; L467-L471 PolarHBondContact O-N 3.06Å; L467-L471 VanDerWaalsContact O-N 3.12Å; F469-L471 PolarHBondContact O-N 2.82Å
472	K	93.5	Very high	88	Confident	114 Å²	114	52.4 Å²	52.4	50%	0.496	32%	0.317	S	S	.	.	H	α-helix	trans	-106.8	-28.8	-168.5	-58.5	-58.5	-173.4	-179.1	0	114	T299 Y300 V303 G468	T299-K472 HydrophobicContact CG2-CB 4.08Å; T299-K472 HydrophobicContact CG2-CD 3.93Å; T299-K472 HydrophobicContact CG2-CG 3.94Å; Y300-K472 VanDerWaalsContact CE1-O 3.23Å; Y300-K472 WeakPolarHBondContact CE1-O 3.32Å; V303-K472 HydrophobicContact CG2-CB 3.89Å; V303-K472 HydrophobicContact CG2-CG 3.96Å; G468-K472 WeakPolarHBondContact O-CB 3.33Å; G468-K472 PolarHBondContact O-N 3.47Å
473	I	93.1	Very high	86.2	Confident	2 Å²	2	57.7 Å²	57.7	1%	0.01	34%	0.342	C	S	.	.	P	Polyproline II helix	trans	-92	121.1	-175.8	-53.9	-58.5	0	0	0	110	Y300 V303 M304 K360 V412 L416 F469	Y300-I473 HydrophobicContact CD1-CD1 4Å; V303-I473 HydrophobicContact CB-CD1 4.24Å; V303-I473 HydrophobicContact CG1-CD1 3.97Å; V303-I473 HydrophobicContact CG1-CG1 3.77Å; M304-I473 HydrophobicContact CG-CD1 4.08Å; M304-I473 HydrophobicContact SD-CD1 3.93Å; M304-I473 HydrophobicContact SD-CG1 4.07Å; K360-I473 WeakPolarHBondContact CD-O 3.42Å; K360-I473 WeakPolarHBondContact CE-O 3.45Å; K360-I473 PolarHBondContact NZ-O 3.13Å; V412-I473 HydrophobicContact CG1-CG2 4.11Å; L416-I473 HydrophobicContact CD2-CD1 4Å; F469-I473 HydrophobicContact CD1-CB 4.3Å; F469-I473 HydrophobicContact CD2-CB 4.17Å; F469-I473 HydrophobicContact CD2-CG1 3.81Å; F469-I473 HydrophobicContact CD2-CG2 4.48Å; F469-I473 HydrophobicContact CE1-CB 4.24Å; F469-I473 HydrophobicContact CE1-CG2 4.16Å; F469-I473 HydrophobicContact CE2-CB 4.12Å; F469-I473 HydrophobicContact CE2-CG1 4.01Å; F469-I473 HydrophobicContact CE2-CG2 3.93Å; F469-I473 HydrophobicContact CG-CB 4.25Å; F469-I473 HydrophobicContact CG-CG1 4.18Å; F469-I473 HydrophobicContact CZ-CB 4.14Å; F469-I473 HydrophobicContact CZ-CG2 3.73Å; F469-I473 WeakPolarHBondContact O-CB 3.45Å; F469-I473 PolarHBondContact O-N 3.37Å; F469-I473 VanDerWaalsContact O-N 3.1Å
474	P	91.2	Very high	84.3	Confident	45 Å²	45	57.3 Å²	57.3	29%	0.292	33%	0.333	S	S	.	.	P	Polyproline II helix	trans	-76.3	159.8	174.6	32.7	-34.8	0	0	0	111	L416 T476	L416-P474 HydrophobicContact CD1-CG 4.18Å; P474-T476 PolarHBondContact O-N 2.96Å
475	E	90	Very high	82.1	Confident	46 Å²	46	57 Å²	57	22%	0.215	33%	0.332	C	S	.	.	P	Polyproline II helix	trans	-59.4	135	166.1	-179.2	54.6	-109.3	0	0	109.8	G358 R359 K360 K477 K479	G358-E475 VanDerWaalsContact CA-CD 3.48Å; G358-E475 WeakPolarHBondContact CA-OE2 3.35Å; R359-E475 VanDerWaalsContact N-CD 3.33Å; R359-E475 PolarHBondContact N-OE1 2.92Å; R359-E475 PolarHBondContact N-OE2 3.21Å; R359-E475 VanDerWaalsContact N-OE2 3.1Å; K360-E475 WeakPolarHBondContact CA-OE2 3.17Å; K360-E475 HydrophobicContact CB-CB 4.42Å; K360-E475 WeakPolarHBondContact CB-OE2 3.14Å; K360-E475 PolarHBondContact N-OE2 3.33Å; E475-K477 HydrophobicContact CG-CB 4.5Å; E475-K477 VanDerWaalsContact OE1-CB 3.23Å; E475-K477 WeakPolarHBondContact OE1-CB 3.32Å; E475-K477 PolarHBondContact OE1-N 2.66Å; E475-K479 WeakPolarHBondContact O-CD 3.38Å; E475-K479 WeakPolarHBondContact O-CE 3.36Å; E475-K479 PolarHBondContact O-NZ 2.04Å
476	T	84.5	Confident	79.8	Confident	11 Å²	11	62.5 Å²	62.5	7%	0.067	36%	0.358	C	S	.	.			trans	-110.6	-21.3	-178.7	65.8	0	0	0	0	112.7	V412 E415 L416 P474 G478 K479	V412-T476 HydrophobicContact CG1-CG2 4.2Å; E415-T476 HydrophobicContact CB-CG2 4.36Å; E415-T476 WeakPolarHBondContact OE2-CB 3.27Å; E415-T476 PolarHBondContact OE2-OG1 3.47Å; L416-T476 HydrophobicContact CD1-CG2 4.46Å; P474-T476 PolarHBondContact O-N 2.96Å; T476-G478 PolarHBondContact O-N 2.95Å; T476-K479 WeakPolarHBondContact O-CB 3.34Å; T476-K479 PolarHBondContact O-N 3.13Å; T476-K479 VanDerWaalsContact O-N 3.14Å
477	K	77.2	Confident	77.5	Confident	40 Å²	40	65.4 Å²	65.4	17%	0.174	37%	0.371	C	S	.	.	T	Hydrogen-bonded Turn	trans	-58.4	130.2	-177.5	-171	176	-178	163.3	0	111.5	D351 V354 M357 R359 E475 K479	D351-K477 WeakPolarHBondContact O-CE 3.49Å; D351-K477 PolarHBondContact O-NZ 3.47Å; D351-K477 WeakPolarHBondContact OD1-CE 3.05Å; D351-K477 IonicContact OD1-NZ 2.79Å; D351-K477 PolarHBondContact OD1-NZ 2.97Å; V354-K477 PolarHBondContact O-NZ 3.06Å; M357-K477 WeakPolarHBondContact O-CD 3.44Å; M357-K477 WeakPolarHBondContact O-CE 3.24Å; M357-K477 PolarHBondContact O-NZ 3.29Å; R359-K477 HydrophobicContact CG-CB 4.21Å; E475-K477 HydrophobicContact CG-CB 4.5Å; E475-K477 VanDerWaalsContact OE1-CB 3.23Å; E475-K477 WeakPolarHBondContact OE1-CB 3.32Å; E475-K477 PolarHBondContact OE1-N 2.66Å; K477-K479 PolarHBondContact O-N 3.46Å; K477-K479 VanDerWaalsContact O-N 3.16Å
478	G	74.4	Confident	75.2	Confident	85 Å²	85	66 Å²	66	88%	0.876	37%	0.366	S	S	*	.	T	Hydrogen-bonded Turn	trans	70.8	1.3	177.5	0	0	0	0	0	115.1	T476	T476-G478 PolarHBondContact O-N 2.95Å
479	K	76.1	Confident	73.1	Confident	125 Å²	125	71.7 Å²	71.7	54%	0.543	39%	0.385	S	S	.	.	P	Polyproline II helix	trans	-84	148.6	176.4	-64.2	-169.3	-178.5	167.9	0	110.9	E475 T476 K477 L481	E475-K479 WeakPolarHBondContact O-CD 3.38Å; E475-K479 WeakPolarHBondContact O-CE 3.36Å; E475-K479 PolarHBondContact O-NZ 2.04Å; T476-K479 WeakPolarHBondContact O-CB 3.34Å; T476-K479 PolarHBondContact O-N 3.13Å; T476-K479 VanDerWaalsContact O-N 3.14Å; K477-K479 PolarHBondContact O-N 3.46Å; K477-K479 VanDerWaalsContact O-N 3.16Å; K479-L481 PolarHBondContact O-N 3.03Å
480	A	71.5	Confident	71.3	Confident	93 Å²	93	76.2 Å²	76.2	77%	0.769	41%	0.408	S	S	*	.	P	Polyproline II helix	trans	-57.6	132.4	172.3	0	0	0	0	0	109.8
481	L	66.6	Low	69.6	Low	72 Å²	72	77.3 Å²	77.3	38%	0.377	42%	0.417	S	S	.	.	P	Polyproline II helix	trans	-59.6	134.7	176.2	-77.4	173.2	0	0	0	109.6	E415 K479 E483	E415-L481 HydrophobicContact CB-CD2 4.27Å; E415-L481 HydrophobicContact CG-CD2 3.87Å; K479-L481 PolarHBondContact O-N 3.03Å; L481-E483 PolarHBondContact O-N 3.17Å
482	P	63.5	Low	68	Low	32 Å²	32	75.3 Å²	75.3	21%	0.208	41%	0.407	C	S	.	.			trans	-58.2	116	175.9	-22.8	32	0	0	0	110.2	E415 P418 R422	E415-P482 WeakPolarHBondContact O-CD 3.22Å; E415-P482 WeakPolarHBondContact O-CG 3.03Å; P418-P482 HydrophobicContact CG-CB 4.39Å; R422-P482 PolarHBondContact NH2-O 3Å
483	E	59.9	Low	66.8	Low	110 Å²	110	77.6 Å²	77.6	51%	0.514	42%	0.417	S	S	.	.			trans	-94.2	136.3	172.2	-76.9	-168.6	174.6	0	0	110.8	L481 S485 Q486 E487	L481-E483 PolarHBondContact O-N 3.17Å; E483-S485 PolarHBondContact O-N 3.19Å; E483-Q486 PolarHBondContact O-N 3.16Å; E483-Q486 VanDerWaalsContact O-N 3.1Å; E483-E487 PolarHBondContact O-N 3.4Å
484	E	58	Low	65.9	Low	32 Å²	32	84 Å²	84	15%	0.15	45%	0.445	C	S	.	.	H	α-helix	trans	-58.3	-32.2	179.3	-171.3	169.2	-173.3	0	0	112.5	V283 R286 Q486 R488	V283-E484 VanDerWaalsContact CG1-OE2 3.28Å; V283-E484 WeakPolarHBondContact CG1-OE2 3.44Å; R286-E484 IonicContact CZ-OE1 3.67Å; R286-E484 IonicContact NE-OE1 3.59Å; R286-E484 IonicContact NH2-OE1 3.83Å; R286-E484 PolarHBondContact NH2-OE1 3.4Å; E484-Q486 VanDerWaalsContact C-N 3.34Å; E484-Q486 PolarHBondContact O-N 3.26Å; E484-R488 VanDerWaalsContact O-CB 3.32Å; E484-R488 WeakPolarHBondContact O-CB 3.5Å; E484-R488 PolarHBondContact O-N 3.25Å; E484-R488 VanDerWaalsContact O-N 3.13Å; E484-R488 IonicContact OE1-CZ 3.81Å; E484-R488 IonicContact OE1-NH2 2.66Å; E484-R488 PolarHBondContact OE1-NH2 3.42Å
485	S	51.3	Low	65.1	Low	60 Å²	60	87.7 Å²	87.7	42%	0.42	46%	0.459	S	S	.	.	H	α-helix	trans	-65.9	-34.8	179.1	76.9	0	0	0	0	112.4	E483 K489	E483-S485 PolarHBondContact O-N 3.19Å; S485-K489 WeakPolarHBondContact O-CB 3.29Å; S485-K489 WeakPolarHBondContact O-CD 3.45Å; S485-K489 WeakPolarHBondContact O-CG 3.49Å; S485-K489 PolarHBondContact O-N 3.01Å
486	Q	48.7	Very low	64.5	Low	120 Å²	120	91 Å²	91	56%	0.561	48%	0.476	S	S	*	.	H	α-helix	trans	-79.3	-44	-178.6	-70.2	-164.8	-17.1	0	0	111.9	E483 E484 R488 K489 I490	E483-Q486 PolarHBondContact O-N 3.16Å; E483-Q486 VanDerWaalsContact O-N 3.1Å; E484-Q486 VanDerWaalsContact C-N 3.34Å; E484-Q486 PolarHBondContact O-N 3.26Å; Q486-R488 PolarHBondContact O-N 3.09Å; Q486-K489 PolarHBondContact O-N 3.45Å; Q486-I490 VanDerWaalsContact O-CG1 3.26Å; Q486-I490 WeakPolarHBondContact O-CG1 2.97Å; Q486-I490 PolarHBondContact O-N 3.49Å
487	E	50.8	Low	64.4	Low	89 Å²	89	99.2 Å²	99.2	42%	0.416	51%	0.506	S	S	.	.	H	α-helix	trans	-65.1	-39.4	177.8	-76.8	-172.9	164.7	0	0	112.2	P418 E483 I490 S491	P418-E487 WeakPolarHBondContact CG-OE2 3.49Å; E483-E487 PolarHBondContact O-N 3.4Å; E487-I490 PolarHBondContact O-N 3.26Å; E487-S491 WeakPolarHBondContact O-CB 3.36Å; E487-S491 PolarHBondContact O-N 3.27Å
488	R	49.2	Very low	64.7	Low	123 Å²	123	106 Å²	106	46%	0.464	53%	0.531	S	S	.	.	H	α-helix	trans	-64.7	-46.7	176	-143.5	-176.8	-69.1	-142.3	5.6	110.9	E484 Q486 I490 S491 D492	E484-R488 VanDerWaalsContact O-CB 3.32Å; E484-R488 WeakPolarHBondContact O-CB 3.5Å; E484-R488 PolarHBondContact O-N 3.25Å; E484-R488 VanDerWaalsContact O-N 3.13Å; E484-R488 IonicContact OE1-CZ 3.81Å; E484-R488 IonicContact OE1-NH2 2.66Å; E484-R488 PolarHBondContact OE1-NH2 3.42Å; Q486-R488 PolarHBondContact O-N 3.09Å; R488-I490 VanDerWaalsContact C-N 3.29Å; R488-I490 PolarHBondContact O-N 3.32Å; R488-S491 PolarHBondContact O-N 2.7Å; R488-S491 VanDerWaalsContact O-N 3.16Å; R488-D492 WeakPolarHBondContact O-CB 3.36Å; R488-D492 PolarHBondContact O-N 3.38Å
489	K	49.7	Very low	65.3	Low	139 Å²	139	105.7 Å²	105.7	60%	0.604	51%	0.509	S	S	*	.	H	α-helix	trans	-56.6	-38.9	173.8	-77.8	174.3	-176.1	-178.5	0	113.1	S485 Q486 K493	S485-K489 WeakPolarHBondContact O-CB 3.29Å; S485-K489 WeakPolarHBondContact O-CD 3.45Å; S485-K489 WeakPolarHBondContact O-CG 3.49Å; S485-K489 PolarHBondContact O-N 3.01Å; Q486-K489 PolarHBondContact O-N 3.45Å; K489-K493 VanDerWaalsContact O-CB 3.3Å; K489-K493 WeakPolarHBondContact O-CB 3.49Å; K489-K493 VanDerWaalsContact O-CG 3.3Å; K489-K493 WeakPolarHBondContact O-CG 3.2Å; K489-K493 PolarHBondContact O-N 3.09Å
490	I	58.1	Low	65.6	Low	96 Å²	96	102.9 Å²	102.9	49%	0.492	50%	0.504	S	S	.	.	H	α-helix	trans	-72.2	-42.6	177.8	-66.6	164.7	0	0	0	111.1	Q486 E487 R488 K493 K494	Q486-I490 VanDerWaalsContact O-CG1 3.26Å; Q486-I490 WeakPolarHBondContact O-CG1 2.97Å; Q486-I490 PolarHBondContact O-N 3.49Å; E487-I490 PolarHBondContact O-N 3.26Å; R488-I490 VanDerWaalsContact C-N 3.29Å; R488-I490 PolarHBondContact O-N 3.32Å; I490-K493 PolarHBondContact O-N 3.2Å; I490-K494 WeakPolarHBondContact O-CG 3.49Å; I490-K494 PolarHBondContact O-N 3.24Å
491	S	59	Low	66.5	Low	67 Å²	67	103 Å²	103	47%	0.469	49%	0.492	S	S	.	.	H	α-helix	trans	-62.8	-48.4	176.9	-172.7	0	0	0	0	111.1	E487 R488 K493 K494 M495	E487-S491 WeakPolarHBondContact O-CB 3.36Å; E487-S491 PolarHBondContact O-N 3.27Å; R488-S491 PolarHBondContact O-N 2.7Å; R488-S491 VanDerWaalsContact O-N 3.16Å; S491-K493 PolarHBondContact O-N 3.46Å; S491-K494 PolarHBondContact O-N 2.8Å; S491-K494 VanDerWaalsContact O-N 3.15Å; S491-M495 WeakPolarHBondContact O-CB 3.11Å; S491-M495 PolarHBondContact O-N 2.89Å
492	D	62.3	Low	67.5	Low	81 Å²	81	104.8 Å²	104.8	43%	0.433	50%	0.498	S	S	.	.	H	α-helix	trans	-61.6	-44.2	178	-63.7	-15.9	0	0	0	110	R488 K494 M495 M496	R488-D492 WeakPolarHBondContact O-CB 3.36Å; R488-D492 PolarHBondContact O-N 3.38Å; D492-K494 PolarHBondContact O-N 2.93Å; D492-M495 PolarHBondContact O-N 2.82Å; D492-M496 WeakPolarHBondContact O-CB 3.26Å; D492-M496 WeakPolarHBondContact O-CG 3.38Å; D492-M496 PolarHBondContact O-N 3.02Å
493	K	68	Low	68.7	Low	161 Å²	161	106.9 Å²	106.9	70%	0.7	51%	0.507	S	S	*	.	H	α-helix	trans	-59.4	-41.3	173.5	-84.5	-175.4	175.9	-172.4	0	113.3	K489 I490 S491 R497	K489-K493 VanDerWaalsContact O-CB 3.3Å; K489-K493 WeakPolarHBondContact O-CB 3.49Å; K489-K493 VanDerWaalsContact O-CG 3.3Å; K489-K493 WeakPolarHBondContact O-CG 3.2Å; K489-K493 PolarHBondContact O-N 3.09Å; I490-K493 PolarHBondContact O-N 3.2Å; S491-K493 PolarHBondContact O-N 3.46Å; K493-R497 WeakPolarHBondContact O-CB 3.34Å; K493-R497 PolarHBondContact O-N 2.74Å
494	K	73.5	Confident	70.1	Confident	137 Å²	137	104.1 Å²	104.1	60%	0.596	50%	0.503	S	S	*	.	H	α-helix	trans	-69.1	-40.1	177.7	-78.8	-175.9	179.2	-176.9	0	112	I490 S491 D492 R497 R498	I490-K494 WeakPolarHBondContact O-CG 3.49Å; I490-K494 PolarHBondContact O-N 3.24Å; S491-K494 PolarHBondContact O-N 2.8Å; S491-K494 VanDerWaalsContact O-N 3.15Å; D492-K494 PolarHBondContact O-N 2.93Å; K494-R497 PolarHBondContact O-N 3.12Å; K494-R498 WeakPolarHBondContact O-CG 3.38Å; K494-R498 PolarHBondContact O-N 2.98Å
495	M	75.3	Confident	71.7	Confident	122 Å²	122	108.6 Å²	108.6	60%	0.601	52%	0.524	S	S	*	.	H	α-helix	trans	-62.9	-48.2	175.4	-175.5	178.2	120.3	0	0	110.4	S491 D492 R497 R498 L499	S491-M495 WeakPolarHBondContact O-CB 3.11Å; S491-M495 PolarHBondContact O-N 2.89Å; D492-M495 PolarHBondContact O-N 2.82Å; M495-R497 VanDerWaalsContact C-N 3.29Å; M495-R497 PolarHBondContact O-N 2.84Å; M495-R498 PolarHBondContact O-N 3.32Å; M495-R498 VanDerWaalsContact O-N 3.15Å; M495-L499 WeakPolarHBondContact O-CB 3.43Å; M495-L499 PolarHBondContact O-N 3.44Å
496	M	76	Confident	73.6	Confident	115 Å²	115	112 Å²	112	57%	0.567	53%	0.533	S	S	*	.	H	α-helix	trans	-58.9	-39.7	175	-70	-57.2	-64.8	0	0	112	D492 L499 S500	D492-M496 WeakPolarHBondContact O-CB 3.26Å; D492-M496 WeakPolarHBondContact O-CG 3.38Å; D492-M496 PolarHBondContact O-N 3.02Å; M496-L499 PolarHBondContact O-N 2.87Å; M496-S500 WeakPolarHBondContact O-CB 3.39Å; M496-S500 PolarHBondContact O-N 3.37Å; M496-S500 PolarHBondContact O-OG 3.3Å
497	R	83.1	Confident	75.6	Confident	184 Å²	184	112.7 Å²	112.7	69%	0.694	54%	0.536	S	S	*	.	H	α-helix	trans	-68.3	-35.6	176.7	-167.6	176.5	-178	-173.8	0.3	113.1	K493 K494 M495 S500 L501	K493-R497 WeakPolarHBondContact O-CB 3.34Å; K493-R497 PolarHBondContact O-N 2.74Å; K494-R497 PolarHBondContact O-N 3.12Å; M495-R497 VanDerWaalsContact C-N 3.29Å; M495-R497 PolarHBondContact O-N 2.84Å; R497-S500 WeakPolarHBondContact CA-OG 3.42Å; R497-S500 PolarHBondContact O-OG 3.39Å; R497-L501 HydrophobicContact CG-CD1 4.48Å; R497-L501 WeakPolarHBondContact O-CD1 3.25Å; R497-L501 VanDerWaalsContact O-CG 3.25Å; R497-L501 WeakPolarHBondContact O-CG 3.49Å; R497-L501 PolarHBondContact O-N 3.14Å; R497-L501 VanDerWaalsContact O-N 3.13Å
498	R	83.4	Confident	77.5	Confident	183 Å²	183	110.5 Å²	110.5	69%	0.691	53%	0.534	S	S	*	.	H	α-helix	trans	-69.1	-44.7	174.4	-76.4	178.5	177.7	-175.5	-3.7	111	K494 M495 S500 L501 Q502	K494-R498 WeakPolarHBondContact O-CG 3.38Å; K494-R498 PolarHBondContact O-N 2.98Å; M495-R498 PolarHBondContact O-N 3.32Å; M495-R498 VanDerWaalsContact O-N 3.15Å; R498-S500 VanDerWaalsContact C-N 3.32Å; R498-S500 PolarHBondContact O-N 2.99Å; R498-L501 PolarHBondContact O-N 3Å; R498-L501 VanDerWaalsContact O-N 3.16Å; R498-Q502 WeakPolarHBondContact O-CG 3.28Å; R498-Q502 PolarHBondContact O-N 3.38Å
499	L	86.9	Confident	79.5	Confident	79 Å²	79	110.4 Å²	110.4	41%	0.414	54%	0.538	S	S	.	.	H	α-helix	trans	-61.3	-42.6	176.9	-167	71.9	0	0	0	110.9	M495 M496 L501 Q502 I503	M495-L499 WeakPolarHBondContact O-CB 3.43Å; M495-L499 PolarHBondContact O-N 3.44Å; M496-L499 PolarHBondContact O-N 2.87Å; L499-L501 VanDerWaalsContact C-N 3.3Å; L499-L501 PolarHBondContact O-N 2.99Å; L499-Q502 PolarHBondContact O-N 3.29Å; L499-I503 HydrophobicContact CG-CD1 4.06Å; L499-I503 WeakPolarHBondContact O-CD1 3.33Å; L499-I503 VanDerWaalsContact O-CG1 3.24Å; L499-I503 WeakPolarHBondContact O-CG1 3.23Å; L499-I503 PolarHBondContact O-N 2.98Å
500	S	83.6	Confident	81.4	Confident	65 Å²	65	112.7 Å²	112.7	46%	0.455	54%	0.543	S	S	.	.	H	α-helix	trans	-64.8	-33.3	176	63.5	0	0	0	0	113.2	M496 R497 R498 A504	M496-S500 WeakPolarHBondContact O-CB 3.39Å; M496-S500 PolarHBondContact O-N 3.37Å; M496-S500 PolarHBondContact O-OG 3.3Å; R497-S500 WeakPolarHBondContact CA-OG 3.42Å; R497-S500 PolarHBondContact O-OG 3.39Å; R498-S500 VanDerWaalsContact C-N 3.32Å; R498-S500 PolarHBondContact O-N 2.99Å; S500-A504 WeakPolarHBondContact O-CB 3.48Å; S500-A504 PolarHBondContact O-N 3.5Å; S500-A504 VanDerWaalsContact O-N 3.08Å
501	L	89.5	Confident	82.9	Confident	97 Å²	97	110.8 Å²	110.8	51%	0.508	54%	0.538	S	S	.	.	H	α-helix	trans	-71.6	-41.4	175.8	-75.1	165.9	0	0	0	111.4	R497 R498 L499 A504 E505	R497-L501 HydrophobicContact CG-CD1 4.48Å; R497-L501 WeakPolarHBondContact O-CD1 3.25Å; R497-L501 VanDerWaalsContact O-CG 3.25Å; R497-L501 WeakPolarHBondContact O-CG 3.49Å; R497-L501 PolarHBondContact O-N 3.14Å; R497-L501 VanDerWaalsContact O-N 3.13Å; R498-L501 PolarHBondContact O-N 3Å; R498-L501 VanDerWaalsContact O-N 3.16Å; L499-L501 VanDerWaalsContact C-N 3.3Å; L499-L501 PolarHBondContact O-N 2.99Å; L501-A504 PolarHBondContact O-N 2.61Å; L501-E505 WeakPolarHBondContact O-CG 3.38Å; L501-E505 PolarHBondContact O-N 2.84Å
502	Q	87.5	Confident	84.2	Confident	109 Å²	109	113 Å²	113	51%	0.509	54%	0.543	S	S	.	.	H	α-helix	trans	-62.7	-44.2	175.2	-74.1	179	-44.2	0	0	111.8	R498 L499 A504 E505 E506	R498-Q502 WeakPolarHBondContact O-CG 3.28Å; R498-Q502 PolarHBondContact O-N 3.38Å; L499-Q502 PolarHBondContact O-N 3.29Å; Q502-A504 VanDerWaalsContact C-N 3.31Å; Q502-A504 PolarHBondContact O-N 2.95Å; Q502-E505 PolarHBondContact O-N 2.69Å; Q502-E506 WeakPolarHBondContact O-CB 3.03Å; Q502-E506 WeakPolarHBondContact O-CG 3.44Å; Q502-E506 PolarHBondContact O-N 3.37Å
503	I	89.7	Confident	85.4	Confident	75 Å²	75	114.9 Å²	114.9	39%	0.385	55%	0.552	S	S	.	*	H	α-helix	trans	-61	-42.8	175.5	-67.2	164.5	0	0	0	110.4	L499 E505 E506 E507	L499-I503 HydrophobicContact CG-CD1 4.06Å; L499-I503 WeakPolarHBondContact O-CD1 3.33Å; L499-I503 VanDerWaalsContact O-CG1 3.24Å; L499-I503 WeakPolarHBondContact O-CG1 3.23Å; L499-I503 PolarHBondContact O-N 2.98Å; I503-E505 PolarHBondContact O-N 3.31Å; I503-E506 PolarHBondContact O-N 3.24Å; I503-E507 HydrophobicContact CG2-CG 4.41Å; I503-E507 WeakPolarHBondContact O-CB 3.23Å; I503-E507 VanDerWaalsContact O-CG 3.3Å; I503-E507 WeakPolarHBondContact O-CG 3.24Å; I503-E507 PolarHBondContact O-N 3.44Å
504	A	89.4	Confident	86.3	Confident	52 Å²	52	113.5 Å²	113.5	43%	0.43	55%	0.551	S	S	.	*	H	α-helix	trans	-66.3	-36.1	177.8	0	0	0	0	0	113	S500 L501 Q502 A508	S500-A504 WeakPolarHBondContact O-CB 3.48Å; S500-A504 PolarHBondContact O-N 3.5Å; S500-A504 VanDerWaalsContact O-N 3.08Å; L501-A504 PolarHBondContact O-N 2.61Å; Q502-A504 VanDerWaalsContact C-N 3.31Å; Q502-A504 PolarHBondContact O-N 2.95Å; A504-A508 WeakPolarHBondContact O-CB 3.38Å; A504-A508 PolarHBondContact O-N 3.37Å
505	E	91	Very high	86.7	Confident	126 Å²	126	117.6 Å²	117.6	59%	0.589	56%	0.563	S	S	*	*	H	α-helix	trans	-67	-46.2	173.6	-77.7	173.7	173.7	0	0	111.3	L501 Q502 I503 E507 A508 E509	L501-E505 WeakPolarHBondContact O-CG 3.38Å; L501-E505 PolarHBondContact O-N 2.84Å; Q502-E505 PolarHBondContact O-N 2.69Å; I503-E505 PolarHBondContact O-N 3.31Å; E505-E507 VanDerWaalsContact C-N 3.34Å; E505-E507 PolarHBondContact O-N 2.91Å; E505-A508 PolarHBondContact O-N 3.15Å; E505-E509 WeakPolarHBondContact O-CG 2.86Å; E505-E509 PolarHBondContact O-N 2.79Å
506	E	90.6	Very high	86.9	Confident	133 Å²	133	121.6 Å²	121.6	62%	0.621	58%	0.58	S	S	*	*	H	α-helix	trans	-60.8	-41.4	175.4	-75.4	178.8	178.6	0	0	111.8	Q502 I503 R510	Q502-E506 WeakPolarHBondContact O-CB 3.03Å; Q502-E506 WeakPolarHBondContact O-CG 3.44Å; Q502-E506 PolarHBondContact O-N 3.37Å; I503-E506 PolarHBondContact O-N 3.24Å; E506-R510 VanDerWaalsContact O-CB 3.28Å; E506-R510 WeakPolarHBondContact O-CB 3.48Å; E506-R510 PolarHBondContact O-N 3.37Å
507	E	91.8	Very high	87.4	Confident	133 Å²	133	122 Å²	122	62%	0.621	58%	0.581	S	S	*	*	H	α-helix	trans	-64.7	-40.5	174.8	-76.5	178.5	176.9	0	0	112	I503 E505 R510 S511	I503-E507 HydrophobicContact CG2-CG 4.41Å; I503-E507 WeakPolarHBondContact O-CB 3.23Å; I503-E507 VanDerWaalsContact O-CG 3.3Å; I503-E507 WeakPolarHBondContact O-CG 3.24Å; I503-E507 PolarHBondContact O-N 3.44Å; E505-E507 VanDerWaalsContact C-N 3.34Å; E505-E507 PolarHBondContact O-N 2.91Å; E507-R510 PolarHBondContact O-N 3.4Å; E507-S511 WeakPolarHBondContact O-CB 3.38Å; E507-S511 PolarHBondContact O-N 3.02Å
508	A	90.5	Very high	87.7	Confident	44 Å²	44	118.7 Å²	118.7	36%	0.364	58%	0.575	S	S	.	*	H	α-helix	trans	-65.4	-46	176.7	0	0	0	0	0	111.8	A504 E505 R510 S511 M512	A504-A508 WeakPolarHBondContact O-CB 3.38Å; A504-A508 PolarHBondContact O-N 3.37Å; E505-A508 PolarHBondContact O-N 3.15Å; A508-R510 PolarHBondContact O-N 2.92Å; A508-S511 PolarHBondContact O-N 2.02Å; A508-S511 PolarHBondContact O-OG 3.1Å; A508-M512 PolarHBondContact O-N 3.37Å
509	E	90.1	Very high	87.9	Confident	121 Å²	121	115.1 Å²	115.1	57%	0.565	57%	0.568	S	S	*	*	H	α-helix	trans	-59.9	-44.8	174.9	-74.4	-176	173.3	0	0	111.7	E505 S511 M512 L513	E505-E509 WeakPolarHBondContact O-CG 2.86Å; E505-E509 PolarHBondContact O-N 2.79Å; E509-S511 VanDerWaalsContact C-N 3.29Å; E509-S511 PolarHBondContact O-N 2.92Å; E509-M512 HydrophobicContact CG-CE 4.48Å; E509-M512 PolarHBondContact O-N 3.16Å; E509-M512 VanDerWaalsContact O-N 3.17Å; E509-L513 PolarHBondContact O-N 3.38Å
510	R	90.7	Very high	88	Confident	186 Å²	186	117.2 Å²	117.2	70%	0.702	58%	0.577	S	S	*	*	H	α-helix	trans	-61.8	-38.5	177.2	-159.6	177.4	-164.1	-153.3	3.1	111.9	E506 E507 A508 L513 I514	E506-R510 VanDerWaalsContact O-CB 3.28Å; E506-R510 WeakPolarHBondContact O-CB 3.48Å; E506-R510 PolarHBondContact O-N 3.37Å; E507-R510 PolarHBondContact O-N 3.4Å; A508-R510 PolarHBondContact O-N 2.92Å; R510-L513 PolarHBondContact O-N 2.85Å; R510-I514 HydrophobicContact CG-CD1 4.42Å; R510-I514 WeakPolarHBondContact O-CD1 3.13Å; R510-I514 VanDerWaalsContact O-CG1 3.3Å; R510-I514 WeakPolarHBondContact O-CG1 3.49Å; R510-I514 PolarHBondContact O-N 3.12Å; R510-I514 VanDerWaalsContact O-N 3.15Å
511	S	88.9	Confident	88.2	Confident	56 Å²	56	120.5 Å²	120.5	39%	0.392	59%	0.585	S	S	.	*	H	α-helix	trans	-69	-32.7	176.7	78.3	0	0	0	0	113.2	E507 A508 E509 R515	E507-S511 WeakPolarHBondContact O-CB 3.38Å; E507-S511 PolarHBondContact O-N 3.02Å; A508-S511 PolarHBondContact O-N 2.02Å; A508-S511 PolarHBondContact O-OG 3.1Å; E509-S511 VanDerWaalsContact C-N 3.29Å; E509-S511 PolarHBondContact O-N 2.92Å; S511-R515 WeakPolarHBondContact O-CG 3.49Å; S511-R515 PolarHBondContact O-N 2.93Å
512	M	87.5	Confident	88.2	Confident	114 Å²	114	122.1 Å²	122.1	56%	0.562	59%	0.59	S	S	*	*	H	α-helix	trans	-70.8	-41.5	174.5	-73.9	-170.2	-74.6	0	0	111.6	A508 E509 I514 R515 Q516	A508-M512 PolarHBondContact O-N 3.37Å; E509-M512 HydrophobicContact CG-CE 4.48Å; E509-M512 PolarHBondContact O-N 3.16Å; E509-M512 VanDerWaalsContact O-N 3.17Å; M512-I514 VanDerWaalsContact C-N 3.32Å; M512-I514 PolarHBondContact O-N 3.24Å; M512-R515 PolarHBondContact O-N 3.12Å; M512-R515 VanDerWaalsContact O-N 3.16Å; M512-Q516 PolarHBondContact O-N 3.03Å; M512-Q516 VanDerWaalsContact O-N 3.16Å
513	L	85.8	Confident	88.2	Confident	120 Å²	120	123 Å²	123	63%	0.628	60%	0.596	S	S	*	*	H	α-helix	trans	-64.1	-32.2	175.7	-74.1	169.4	0	0	0	113.5	E509 R510 R515	E509-L513 PolarHBondContact O-N 3.38Å; R510-L513 PolarHBondContact O-N 2.85Å; L513-R515 VanDerWaalsContact C-N 3.32Å
514	I	86.8	Confident	88.1	Confident	133 Å²	133	126.7 Å²	126.7	68%	0.682	61%	0.612	S	S	*	*	H	α-helix	trans	-74.3	-24.7	175.6	-68.4	165.8	0	0	0	111.8	R510 M512	R510-I514 HydrophobicContact CG-CD1 4.42Å; R510-I514 WeakPolarHBondContact O-CD1 3.13Å; R510-I514 VanDerWaalsContact O-CG1 3.3Å; R510-I514 WeakPolarHBondContact O-CG1 3.49Å; R510-I514 PolarHBondContact O-N 3.12Å; R510-I514 VanDerWaalsContact O-N 3.15Å; M512-I514 VanDerWaalsContact C-N 3.32Å; M512-I514 PolarHBondContact O-N 3.24Å
515	R	83.4	Confident	88	Confident	222 Å²	222	132.9 Å²	132.9	84%	0.838	63%	0.628	S	S	*	*	H	α-helix	trans	-85.5	-26.2	180	-77.9	-179.2	178.7	-174.3	1.7	113.7	S511 M512 L513	S511-R515 WeakPolarHBondContact O-CG 3.49Å; S511-R515 PolarHBondContact O-N 2.93Å; M512-R515 PolarHBondContact O-N 3.12Å; M512-R515 VanDerWaalsContact O-N 3.16Å; L513-R515 VanDerWaalsContact C-N 3.32Å
516	Q	78.9	Confident	87.7	Confident	207 Å²	207	133.5 Å²	133.5	97%	0.967	63%	0.631	S	S	*	*			trans	-74.4	0	169.5	-72.5	-179	-22.3	0	0	109.9	M512	M512-Q516 PolarHBondContact O-N 3.03Å; M512-Q516 VanDerWaalsContact O-N 3.16Å

Retrieved 516 of 516 residues in 304.3 ms (Link to these results)

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