A0A077YZJ3_TRITR Loading...

Deoxyribonuclease (DNase) II

AlphaFold DB , UniProt , Accession A0A077YZJ3, Species TRITR (Trichuris trichiura, Whipworm), Gene n/a, Length 358 aa.

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Site Residue pLDDT pLDDT confidence pLDDT10 pLDDT10 confidence SASA SASA [Ų] SASA10 SASA10 [Ų] RSA RSA unformatted RSA10 RSA10 unformatted Surface Surface10 (not used) Disorder (not used) Disorder Sec. str. Secondary structure Isomer Phi (φ) Psi (ψ) Omega (ω) Chi 1 (χ1) Chi 2 (χ2) Chi 3 (χ3) Chi 4 (χ4) Chi 5 (χ5) Tau (τ) Contacts (colored by PAE) Contact details
1M38.5Very low41.4Very low244 Ų244156.1 Ų156.1100%1.20284%0.84SS**  097.10-75.9178.8171.500108.3
2I39.7Very low41.5Very low145 Ų145159 Ų15974%0.74484%0.839SS**  trans-124.9104.7173.7-63.7175.3000105.7Y4I2-Y4 HydrophobicContact CG2-CE2 4.19Å
3K38.7Very low41.5Very low212 Ų212151.9 Ų151.992%0.92283%0.828SS**  trans-83.7111.5177.1-76.7-177.2175.5-179.30107.9A5K3-A5 PolarHBondContact O-N 3.38Å
4Y45.2Very low41.6Very low194 Ų194149.2 Ų149.276%0.76182%0.818SS**  trans-74.7112.4168.7-76.2-87.4000109I2 H6I2-Y4 HydrophobicContact CG2-CE2 4.19Å; Y4-H6 PolarHBondContact O-N 3.49Å
5A42.4Very low41.5Very low97 Ų97147.3 Ų147.380%0.80281%0.813SS**  trans-85.2101.8167.900000108K3 L7K3-A5 PolarHBondContact O-N 3.38Å; A5-L7 PolarHBondContact O-N 3.29Å
6H42.8Very low41.4Very low174 Ų174152.4 Ų152.481%0.80682%0.816SS**  trans-81.4112.8170-85.1-69.1000109.6Y4 G8Y4-H6 PolarHBondContact O-N 3.49Å; H6-G8 PolarHBondContact O-N 3.42Å
7L41.8Very low41.5Very low166 Ų166150.7 Ų150.787%0.86981%0.805SS**  trans-59.4115.9174.5-136.172.6000109.6A5 T9A5-L7 PolarHBondContact O-N 3.29Å; L7-T9 PolarHBondContact O-N 3.38Å
8G41.2Very low41.5Very low73 Ų73146.7 Ų146.775%0.75380%0.796SS**  trans-72.7110.5173.200000110.6H6 T10H6-G8 PolarHBondContact O-N 3.42Å; G8-T10 PolarHBondContact O-N 3.31Å
9T40.9Very low41.3Very low126 Ų126147.7 Ų147.777%0.77380%0.795SS**  trans-75.5103.7166.938.50000109.5L7 L11L7-T9 PolarHBondContact O-N 3.38Å; T9-L11 PolarHBondContact O-N 3.29Å
10T41Very low41.2Very low121 Ų121146.6 Ų146.674%0.74279%0.793SS**  trans-72.1105.5168.326.10000109.6G8 F12G8-T10 PolarHBondContact O-N 3.31Å; T10-F12 PolarHBondContact O-N 3.22Å
11L43.3Very low41.1Very low165 Ų165143.4 Ų143.486%0.86479%0.787SS**  trans-67110.3167.1-98.391.2000109.2T9 G13T9-L11 PolarHBondContact O-N 3.29Å; L11-G13 PolarHBondContact O-N 3.19Å; L11-G13 VanDerWaalsContact O-N 3.13Å
12F42.3Very low41.3Very low191 Ų191136.4 Ų136.484%0.83876%0.762SS**  trans-71.897.5162.5-81.5-91.6000108.8T10 V14T10-F12 PolarHBondContact O-N 3.22Å; F12-V14 PolarHBondContact O-N 3.13Å
13G41.5Very low41.8Very low67 Ų67135.4 Ų135.469%0.69176%0.756SS**  trans-69.4104.9166.700000109.7L11 V15L11-G13 PolarHBondContact O-N 3.19Å; L11-G13 VanDerWaalsContact O-N 3.13Å; G13-V15 PolarHBondContact O-N 3.1Å; G13-V15 VanDerWaalsContact O-N 3.1Å
14V43.3Very low42.5Very low114 Ų114128.4 Ų128.469%0.69173%0.733SS**  trans-71.799.9168.4178.50000107.4F12 W16F12-V14 PolarHBondContact O-N 3.13Å; V14-W16 PolarHBondContact O-N 3.06Å
15V40.1Very low43.5Very low121 Ų121120.6 Ų120.673%0.73371%0.706SS**  trans-71.298.7171.5-179.20000107.5G13 I17G13-V15 PolarHBondContact O-N 3.1Å; G13-V15 VanDerWaalsContact O-N 3.1Å; V15-I17 VanDerWaalsContact C-N 3.29Å; V15-I17 HydrophobicContact CG1-CG1 3.94Å; V15-I17 PolarHBondContact O-N 2.98Å
16W40.5Very low45.7Very low229 Ų229117.2 Ų117.287%0.86767%0.674SS**  trans-67.493.8161.8-77.285.2000107.7V14 A18V14-W16 PolarHBondContact O-N 3.06Å; W16-A18 PolarHBondContact O-N 2.82Å
17I41.6Very low48.2Very low123 Ų123109.1 Ų109.163%0.63164%0.637SS**  trans-68.193.1159.9-58.6177.8000104.8V15 H19V15-I17 VanDerWaalsContact C-N 3.29Å; V15-I17 HydrophobicContact CG1-CG1 3.94Å; V15-I17 PolarHBondContact O-N 2.98Å; I17-H19 PolarHBondContact O-N 2.9Å
18A42.5Very low50.9Low78 Ų78102 Ų10265%0.64560%0.599SS**  trans-58.896.9158.800000105.5W16 V20W16-A18 PolarHBondContact O-N 2.82Å; A18-V20 PolarHBondContact O-N 2.73Å
19H37.7Very low53.5Low167 Ų16798.5 Ų98.577%0.77356%0.564SS**  trans-58.887149.7-75-67.2000104.5I17 A21I17-H19 PolarHBondContact O-N 2.9Å; H19-A21 PolarHBondContact O-N 2.8Å
20V39.9Very low56.2Low124 Ų12493.2 Ų93.275%0.75253%0.529SS*.  trans-52.1102.7148.8-176.90000101.5A18 S22A18-V20 PolarHBondContact O-N 2.73Å; V20-S22 PolarHBondContact O-N 2.75Å
21A38.3Very low58.7Low81 Ų8188.4 Ų88.467%0.66950%0.498SS*.  trans-56.593.4162.100000102.5H19 M23H19-A21 PolarHBondContact O-N 2.8Å; A21-M23 PolarHBondContact O-N 2.66Å
22S42.7Very low61.1Low97 Ų9780.6 Ų80.668%0.67846%0.458SS*.  trans-46.4104.6158.4168.90000101.7V20 S24V20-S22 PolarHBondContact O-N 2.75Å; S22-S24 PolarHBondContact O-N 2.49Å
23M50Low63.5Low124 Ų12477.6 Ų77.661%0.61145%0.446SS*.  trans-63.990.5173.1-69.7-162.19400101.8A21 T25 N35A21-M23 PolarHBondContact O-N 2.66Å; M23-T25 VanDerWaalsContact C-N 3.27Å; M23-T25 PolarHBondContact O-N 3.25Å; M23-N35 HydrophobicContact CE-CB 4.19Å
24S52.6Low65.9Low65 Ų6577.3 Ų77.346%0.45543%0.433SS..  trans-58.1100.1-174170.10000105.9S22 D26 R30S22-S24 PolarHBondContact O-N 2.49Å; S24-D26 PolarHBondContact O-N 3.13Å; S24-R30 PolarHBondContact O-NH1 2.67Å; S24-R30 PolarHBondContact O-NH2 3.13Å
25T67.4Low68.3Low30 Ų3072.2 Ų72.218%0.18440%0.402CS..  trans-78.779.6170.148.20000105.2M23 P97M23-T25 VanDerWaalsContact C-N 3.27Å; M23-T25 PolarHBondContact O-N 3.25Å; T25-P97 WeakPolarHBondContact O-CB 3.34Å; T25-P97 WeakPolarHBondContact O-CG 3.4Å
26D88.1Confident70.8Confident25 Ų2573.1 Ų73.113%0.13440%0.397CS..  trans-91.6158.4177.5-142-38.4000111.5S24 L28 R30 N128 N131S24-D26 PolarHBondContact O-N 3.13Å; D26-L28 PolarHBondContact O-N 2.93Å; D26-R30 PolarHBondContact O-NH2 2.79Å; D26-N128 PolarHBondContact OD1-ND2 3.38Å; D26-N128 PolarHBondContact OD1-OD1 2.99Å; D26-N131 WeakPolarHBondContact OD1-CB 3.23Å; D26-N131 PolarHBondContact OD1-ND2 2.77Å; D26-N131 PolarHBondContact OD2-ND2 2.87Å
27Y95.9Very high73.4Confident5 Ų563.6 Ų63.62%0.0237%0.369CS..SBendtrans-75.570.6176.7-70.3-64000111.6P97 S107 R109 M126 S127 N128 N131 A132 F133Y27-P97 HydrophobicContact CD1-CB 4.1Å; Y27-P97 HydrophobicContact CD1-CG 4.36Å; Y27-P97 HydrophobicContact CE1-CB 3.77Å; Y27-P97 HydrophobicContact CE1-CG 4.47Å; Y27-S107 VanDerWaalsContact CE2-CB 3.46Å; Y27-S107 WeakPolarHBondContact CE2-OG 3.25Å; Y27-R109 PolarHBondContact OH-NH2 2.85Å; Y27-M126 HydrophobicContact CD1-CB 3.39Å; Y27-M126 HydrophobicContact CD1-CG 4.3Å; Y27-M126 HydrophobicContact CE1-CB 3.58Å; Y27-M126 HydrophobicContact CE1-CG 4.14Å; Y27-M126 HydrophobicContact CE1-SD 4.36Å; Y27-M126 HydrophobicContact CG-CB 4.06Å; Y27-S127 VanDerWaalsContact CD2-C 3.48Å; Y27-N128 HydrophobicContact CD2-CB 3.81Å; Y27-N128 HydrophobicContact CE2-CB 4.22Å; Y27-N131 CarbonylContact O-C 3.59Å; Y27-N131 WeakPolarHBondContact O-CB 3.48Å; Y27-A132 CarbonylContact O-C 3.59Å; Y27-A132 WeakPolarHBondContact O-CA 3.16Å; Y27-A132 PolarHBondContact O-N 2.79Å; Y27-F133 HydrophobicContact CD1-CD1 4.21Å; Y27-F133 AromaticContact CD1-CE1 3.71Å; Y27-F133 HydrophobicContact CD1-CE1 3.71Å; Y27-F133 PolarHBondContact O-N 3.29Å
28L97.1Very high76Confident16 Ų1657.9 Ų57.98%0.08434%0.34CS..SBendtrans-127.6150.7171.7-68.6171.8000109.6D26 R30 N131 K223 L225D26-L28 PolarHBondContact O-N 2.93Å; L28-R30 PolarHBondContact O-N 3.17Å; L28-N131 HydrophobicContact CD2-CB 3.85Å; L28-N131 HydrophobicContact CG-CB 3.93Å; L28-K223 HydrophobicContact CD2-CD 3.73Å; L28-L225 HydrophobicContact CD1-CD2 4.28Å
29C97.8Very high78.6Confident0 Ų054.9 Ų54.90%031%0.313CS..  trans-59.5135.1160.8-55.40000109G37 V38 F41 C164 V165 S166C29-G37 CarbonylContact O-C 3.56Å; C29-G37 WeakPolarHBondContact O-CA 3.2Å; C29-V38 HydrophobicContact CB-CG2 4.06Å; C29-V38 WeakPolarHBondContact O-CG2 3.04Å; C29-V38 PolarHBondContact O-N 2.74Å; C29-F41 HydrophobicContact CB-CD1 3.62Å; C29-F41 HydrophobicContact CB-CE1 3.7Å; C29-C164 HydrophobicContact CB-CB 3.93Å; C29-C164 WeakPolarHBondContact CB-SG 3.4Å; C29-C164 WeakPolarHBondContact SG-CB 3.16Å; C29-C164 CovalentContact SG-SG 2.04Å; C29-C164 PolarHBondContact SG-SG 2.82Å; C29-V165 VanDerWaalsContact SG-CA 3.57Å; C29-V165 PolarHBondContact SG-N 2.86Å; C29-S166 WeakPolarHBondContact CB-OG 3.41Å; C29-S166 PolarHBondContact N-OG 2.83Å; C29-S166 PolarHBondContact SG-N 2.86Å; C29-S166 VanDerWaalsContact SG-N 3.39Å
30R96.1Very high81.4Confident15 Ų1547 Ų476%0.05728%0.276CS..BIsolated β-bridgetrans-123.8145-174.5-72.4176.9-176-85.4-8.9113.1S24 D26 L28 N35 K36 M90 R93 T94S24-R30 PolarHBondContact O-NH1 2.67Å; S24-R30 PolarHBondContact O-NH2 3.13Å; D26-R30 PolarHBondContact O-NH2 2.79Å; L28-R30 PolarHBondContact O-N 3.17Å; R30-N35 PolarHBondContact NH1-O 2.96Å; R30-K36 WeakPolarHBondContact CA-O 3.23Å; R30-M90 WeakPolarHBondContact O-CA 2.93Å; R30-M90 VanDerWaalsContact O-CB 3.25Å; R30-M90 WeakPolarHBondContact O-CB 3.04Å; R30-R93 HydrophobicContact CB-CB 3.85Å; R30-R93 WeakPolarHBondContact CD-O 3.29Å; R30-T94 PolarHBondContact N-OG1 2.84Å
31E94.3Very high84.2Confident19 Ų1941.1 Ų41.19%0.08924%0.24CC..  trans-87.5161.8170.765.870.3-139.100112.9E33 S34 N35 K36 V38 M90 R93E31-E33 PolarHBondContact OE2-N 3.26Å; E31-S34 VanDerWaalsContact CD-N 3.34Å; E31-S34 WeakPolarHBondContact OE1-CA 3.39Å; E31-S34 WeakPolarHBondContact OE1-CB 3.24Å; E31-S34 PolarHBondContact OE1-N 3.21Å; E31-S34 PolarHBondContact OE1-OG 2.71Å; E31-S34 PolarHBondContact OE2-N 2.99Å; E31-S34 VanDerWaalsContact OE2-N 3.13Å; E31-N35 WeakPolarHBondContact O-CA 3.41Å; E31-N35 PolarHBondContact OE1-N 3.45Å; E31-K36 HydrophobicContact CG-CB 4.47Å; E31-K36 PolarHBondContact N-O 3.11Å; E31-K36 PolarHBondContact OE1-N 3.08Å; E31-V38 HydrophobicContact CB-CG1 3.79Å; E31-V38 HydrophobicContact CG-CG1 3.81Å; E31-M90 HydrophobicContact CB-CE 4.25Å; E31-R93 VanDerWaalsContact O-CD 3.31Å; E31-R93 WeakPolarHBondContact O-CD 3.21Å
32Q94.1Very high87.1Confident2 Ų237.2 Ų37.21%0.00921%0.208CC..THydrogen-bonded Turntrans-74-47.1-165.8-180160-73.600113.3S80 M82 Q89 M90 R93Q32-S80 PolarHBondContact NE2-OG 3.3Å; Q32-S80 PolarHBondContact OE1-OG 2.86Å; Q32-S80 VanDerWaalsContact OE1-OG 3.11Å; Q32-M82 HydrophobicContact CG-CE 3.81Å; Q32-Q89 HydrophobicContact CG-CB 4.48Å; Q32-Q89 VanDerWaalsContact OE1-CB 3.28Å; Q32-M90 HydrophobicContact CB-CG 3.69Å; Q32-M90 HydrophobicContact CB-SD 4.45Å; Q32-R93 PolarHBondContact O-NE 2.79Å; Q32-R93 PolarHBondContact O-NH2 3.05Å
33E91.6Very high89.8Confident127 Ų12732.6 Ų32.659%0.59318%0.176SC*.THydrogen-bonded Turntrans-81.7-47.9-161.4-59.8-56.6144.900111.2E31E31-E33 PolarHBondContact OE2-N 3.26Å
34S91.8Very high92.1Very high61 Ų6126.7 Ų26.743%0.42715%0.147SC..THydrogen-bonded Turntrans-104.9-0-177.980.10000114.9E31 K36E31-S34 VanDerWaalsContact CD-N 3.34Å; E31-S34 WeakPolarHBondContact OE1-CA 3.39Å; E31-S34 WeakPolarHBondContact OE1-CB 3.24Å; E31-S34 PolarHBondContact OE1-N 3.21Å; E31-S34 PolarHBondContact OE1-OG 2.71Å; E31-S34 PolarHBondContact OE2-N 2.99Å; E31-S34 VanDerWaalsContact OE2-N 3.13Å; S34-K36 PolarHBondContact O-N 2.91Å; S34-K36 VanDerWaalsContact OG-CD 3.26Å; S34-K36 WeakPolarHBondContact OG-CD 3.24Å; S34-K36 WeakPolarHBondContact OG-CG 3.2Å
35N93.7Very high94.2Very high7 Ų723.6 Ų23.64%0.03713%0.125CC..  trans59.316.6-175.5-165.143.4000114.3M23 R30 E31 R93M23-N35 HydrophobicContact CE-CB 4.19Å; R30-N35 PolarHBondContact NH1-O 2.96Å; E31-N35 WeakPolarHBondContact O-CA 3.41Å; E31-N35 PolarHBondContact OE1-N 3.45Å; N35-R93 VanDerWaalsContact CB-NH1 3.33Å; N35-R93 WeakPolarHBondContact OD1-CD 3.42Å; N35-R93 VanDerWaalsContact OD1-CG 3.31Å; N35-R93 WeakPolarHBondContact OD1-CG 3.35Å; N35-R93 PolarHBondContact OD1-NH1 2.88Å
36K93.7Very high95.6Very high141 Ų14122.3 Ų22.361%0.61312%0.117SC*.  trans-76150.5-178.4-74.7178.6-172175.50110.6R30 E31 S34R30-K36 WeakPolarHBondContact CA-O 3.23Å; E31-K36 HydrophobicContact CG-CB 4.47Å; E31-K36 PolarHBondContact N-O 3.11Å; E31-K36 PolarHBondContact OE1-N 3.08Å; S34-K36 PolarHBondContact O-N 2.91Å; S34-K36 VanDerWaalsContact OG-CD 3.26Å; S34-K36 WeakPolarHBondContact OG-CD 3.24Å; S34-K36 WeakPolarHBondContact OG-CG 3.2Å
37G94.7Very high96Very high28 Ų2821.5 Ų21.529%0.28911%0.114SC..BIsolated β-bridgetrans-63.2139.7169.100000110.5C29 L225C29-G37 CarbonylContact O-C 3.56Å; C29-G37 WeakPolarHBondContact O-CA 3.2Å; G37-L225 VanDerWaalsContact C-CD1 3.49Å; G37-L225 WeakPolarHBondContact O-CD1 3.25Å
38V95.8Very high95.9Very high4 Ų426.3 Ų26.32%0.02414%0.135CC..  trans-124.4155.2173.3-69.50000109.8C29 E31 W40 F41 N69 A71 S166C29-V38 HydrophobicContact CB-CG2 4.06Å; C29-V38 WeakPolarHBondContact O-CG2 3.04Å; C29-V38 PolarHBondContact O-N 2.74Å; E31-V38 HydrophobicContact CB-CG1 3.79Å; E31-V38 HydrophobicContact CG-CG1 3.81Å; V38-W40 VanDerWaalsContact C-N 3.26Å; V38-W40 PolarHBondContact O-N 2.82Å; V38-F41 HydrophobicContact CG2-CB 4.4Å; V38-F41 HydrophobicContact CG2-CD1 4.27Å; V38-N69 HydrophobicContact CG1-CB 4.42Å; V38-N69 HydrophobicContact CG2-CB 4.37Å; V38-A71 HydrophobicContact CG1-CB 4.36Å; V38-S166 WeakPolarHBondContact O-CB 3.18Å; V38-S166 PolarHBondContact O-OG 3.21Å
39Q96.8Very high95.5Very high15 Ų1526.7 Ų26.77%0.0714%0.136CC..SBendtrans-68.7-34.4-178-59.7179.5-80.800110.7S70 S166 T222 K223 L225 K229Q39-S70 PolarHBondContact N-OG 3.02Å; Q39-S166 PolarHBondContact O-N 2.82Å; Q39-T222 HydrophobicContact CB-CG2 4.42Å; Q39-T222 PolarHBondContact NE2-OG1 3.45Å; Q39-K223 PolarHBondContact NE2-O 3.12Å; Q39-L225 HydrophobicContact CG-CB 4.42Å; Q39-L225 HydrophobicContact CG-CD1 4.16Å; Q39-L225 HydrophobicContact CG-CG 4.3Å; Q39-K229 PolarHBondContact NE2-O 3.28Å; Q39-K229 PolarHBondContact OE1-O 2.69Å
40W97.7Very high94.8Very high1 Ų132.6 Ų32.60%0.00418%0.175CC..EExtended strand (participates in β ladder)trans-158.4158174.354.8-96.3000110.1V38 L68 N69 S70 A73 F163 C164 V165 I337 L342V38-W40 VanDerWaalsContact C-N 3.26Å; V38-W40 PolarHBondContact O-N 2.82Å; W40-L68 HydrophobicContact CZ3-CB 4.06Å; W40-N69 WeakPolarHBondContact O-CA 3.25Å; W40-S70 PolarHBondContact O-N 2.48Å; W40-A73 HydrophobicContact CH2-CB 3.52Å; W40-A73 HydrophobicContact CZ2-CB 4.17Å; W40-A73 HydrophobicContact CZ3-CB 4.45Å; W40-F163 HydrophobicContact CB-CE2 4.09Å; W40-C164 CarbonylContact C-O 3.54Å; W40-C164 WeakPolarHBondContact CA-O 3.16Å; W40-C164 VanDerWaalsContact CB-O 3.26Å; W40-C164 WeakPolarHBondContact CB-O 3.42Å; W40-V165 HydrophobicContact CB-CG2 4.31Å; W40-I337 HydrophobicContact CD2-CD1 4.23Å; W40-I337 HydrophobicContact CG-CD1 3.93Å; W40-L342 HydrophobicContact CE3-CD1 4.14Å; W40-L342 HydrophobicContact CH2-CB 3.76Å; W40-L342 HydrophobicContact CH2-CD1 3.74Å; W40-L342 HydrophobicContact CH2-CG 4.09Å; W40-L342 HydrophobicContact CZ2-CB 4.18Å; W40-L342 HydrophobicContact CZ2-CD1 4.22Å; W40-L342 HydrophobicContact CZ3-CB 4.49Å; W40-L342 HydrophobicContact CZ3-CD1 3.71Å; W40-L342 HydrophobicContact CZ3-CG 4.33Å
41F98.3Very high93.8Very high0 Ų036.8 Ų36.80%020%0.202CC..EExtended strand (participates in β ladder)trans-140161.4160.869.7-107.7000110.9C29 V38 I43 L68 N69 M90 L91 T94 L135 F163 C164C29-F41 HydrophobicContact CB-CD1 3.62Å; C29-F41 HydrophobicContact CB-CE1 3.7Å; V38-F41 HydrophobicContact CG2-CB 4.4Å; V38-F41 HydrophobicContact CG2-CD1 4.27Å; F41-I43 HydrophobicContact CD2-CD1 4.09Å; F41-I43 HydrophobicContact CD2-CG1 3.89Å; F41-I43 HydrophobicContact CE2-CD1 3.64Å; F41-I43 HydrophobicContact CE2-CG1 3.93Å; F41-I43 HydrophobicContact CZ-CD1 4.46Å; F41-L68 CarbonylContact C-O 3.58Å; F41-L68 VanDerWaalsContact CA-O 3.25Å; F41-L68 WeakPolarHBondContact CA-O 3.23Å; F41-L68 WeakPolarHBondContact CB-O 3.33Å; F41-N69 HydrophobicContact CB-CB 3.84Å; F41-M90 HydrophobicContact CB-CE 3.29Å; F41-M90 HydrophobicContact CD1-CE 4.02Å; F41-M90 HydrophobicContact CD2-CE 4.31Å; F41-M90 HydrophobicContact CG-CE 3.65Å; F41-L91 HydrophobicContact CZ-CD1 4.44Å; F41-T94 HydrophobicContact CE1-CG2 4.33Å; F41-T94 VanDerWaalsContact CE1-OG1 3.3Å; F41-T94 WeakPolarHBondContact CE1-OG1 3.33Å; F41-L135 HydrophobicContact CZ-CD1 4.46Å; F41-F163 WeakPolarHBondContact O-CD2 3.31Å; F41-C164 HydrophobicContact CD1-CB 3.74Å; F41-C164 HydrophobicContact CD2-CB 3.99Å; F41-C164 HydrophobicContact CE1-CB 3.31Å; F41-C164 VanDerWaalsContact CE1-SG 3.57Å; F41-C164 HydrophobicContact CE2-CB 3.62Å; F41-C164 HydrophobicContact CG-CB 4.03Å; F41-C164 HydrophobicContact CZ-CB 3.25Å; F41-C164 PolarHBondContact N-O 3.26Å; F41-C164 PolarHBondContact O-N 2.83Å
42L98.7Very high92.4Very high0 Ų038.7 Ų38.70%021%0.213CC..EExtended strand (participates in β ladder)trans-130.3131.4172.5-171.4164.9000108.6Y67 L68 W77 L161 L162 F163 W316 F346L42-Y67 CarbonylContact O-C 3.49Å; L42-Y67 WeakPolarHBondContact O-CA 3.48Å; L42-Y67 WeakPolarHBondContact O-CB 3.44Å; L42-L68 HydrophobicContact CB-CB 4.47Å; L42-L68 PolarHBondContact N-O 3.15Å; L42-L68 PolarHBondContact O-N 3.28Å; L42-W77 HydrophobicContact CD2-CH2 3.38Å; L42-W77 HydrophobicContact CD2-CZ3 3.7Å; L42-L161 HydrophobicContact CD1-CD1 4.09Å; L42-L161 HydrophobicContact CD2-CD1 3.33Å; L42-L161 HydrophobicContact CG-CD1 3.73Å; L42-L162 CarbonylContact C-O 3.32Å; L42-L162 VanDerWaalsContact CA-O 3.29Å; L42-L162 WeakPolarHBondContact CA-O 3.19Å; L42-F163 HydrophobicContact CB-CD2 4.42Å; L42-W316 HydrophobicContact CD1-CD2 4.48Å; L42-W316 HydrophobicContact CD1-CE3 4.41Å; L42-W316 HydrophobicContact CD1-CH2 3.31Å; L42-W316 HydrophobicContact CD1-CZ2 3.38Å; L42-W316 HydrophobicContact CD1-CZ3 3.87Å; L42-W316 HydrophobicContact CG-CH2 4.31Å; L42-F346 HydrophobicContact CD1-CE2 3.68Å; L42-F346 HydrophobicContact CD1-CZ 3.68Å; L42-F346 HydrophobicContact CD2-CZ 4.35Å
43I98.7Very high91.1Very high0 Ų043.4 Ų43.40%023%0.233CC..EExtended strand (participates in β ladder)trans-113124.7172.4-68.5169.3000108.1F41 K45 F65 F66 I84 M90 L91 L162F41-I43 HydrophobicContact CD2-CD1 4.09Å; F41-I43 HydrophobicContact CD2-CG1 3.89Å; F41-I43 HydrophobicContact CE2-CD1 3.64Å; F41-I43 HydrophobicContact CE2-CG1 3.93Å; F41-I43 HydrophobicContact CZ-CD1 4.46Å; I43-K45 HydrophobicContact CG2-CB 4.37Å; I43-F65 HydrophobicContact CB-CD2 4.45Å; I43-F65 HydrophobicContact CD1-CE2 4.44Å; I43-F65 HydrophobicContact CG1-CD2 4.23Å; I43-F65 HydrophobicContact CG1-CE2 4.29Å; I43-F65 HydrophobicContact CG2-CB 3.83Å; I43-F65 HydrophobicContact CG2-CD2 3.62Å; I43-F65 HydrophobicContact CG2-CE2 4.4Å; I43-F65 HydrophobicContact CG2-CG 3.91Å; I43-F66 WeakPolarHBondContact CA-O 3.48Å; I43-I84 HydrophobicContact CG2-CD1 3.93Å; I43-M90 HydrophobicContact CD1-CB 4.28Å; I43-L91 HydrophobicContact CD1-CB 3.8Å; I43-L162 HydrophobicContact CB-CB 4.24Å; I43-L162 HydrophobicContact CB-CD1 4.06Å; I43-L162 HydrophobicContact CG2-CD1 3.83Å; I43-L162 PolarHBondContact N-O 2.94Å; I43-L162 PolarHBondContact O-N 3.15Å
44Y98.5Very high90Very high0 Ų039.9 Ų39.90%022%0.219CC..EExtended strand (participates in β ladder)trans-102.795.2166.8-144.8-57.1000107.6M46 F65 F66 W77 A159 L161 W262 L287 L296 D301 S303 W305Y44-M46 HydrophobicContact CD1-SD 4.26Å; Y44-F65 CarbonylContact O-C 3.46Å; Y44-F65 VanDerWaalsContact O-CA 3.25Å; Y44-F65 WeakPolarHBondContact O-CA 3.47Å; Y44-F65 WeakPolarHBondContact O-CB 3.31Å; Y44-F66 PolarHBondContact N-O 3.05Å; Y44-F66 PolarHBondContact O-N 3.05Å; Y44-W77 AromaticContact CD2-CH2 3.85Å; Y44-W77 HydrophobicContact CD2-CH2 3.85Å; Y44-W77 HydrophobicContact CD2-CZ2 4.33Å; Y44-W77 HydrophobicContact CG-CH2 4.42Å; Y44-A159 HydrophobicContact CE1-CB 4.05Å; Y44-L161 HydrophobicContact CD2-CD1 4.09Å; Y44-W262 PolarHBondContact OH-NE1 3.24Å; Y44-L287 HydrophobicContact CD1-CD1 4.34Å; Y44-L287 HydrophobicContact CD2-CD1 4.34Å; Y44-L287 HydrophobicContact CG-CD1 3.95Å; Y44-L296 HydrophobicContact CD1-CD2 4.15Å; Y44-L296 HydrophobicContact CE1-CD1 4.11Å; Y44-L296 HydrophobicContact CE1-CD2 3.49Å; Y44-L296 VanDerWaalsContact CE1-CD2 3.49Å; Y44-L296 HydrophobicContact CE1-CG 4.46Å; Y44-L296 HydrophobicContact CE2-CD1 4.13Å; Y44-D301 PolarHBondContact OH-OD2 2.85Å; Y44-S303 PolarHBondContact OH-OG 2.79Å; Y44-W305 AromaticContact CE2-NE1 3.88Å
45K98.1Very high89.2Confident0 Ų042.6 Ų42.60%025%0.245CC..EExtended strand (participates in β ladder)trans-76.7127.6175.5178.7-89.2173.1-162.40107.5I43 G62 F65 I84 W150 A155 R156 K158 A159 Q160 L162I43-K45 HydrophobicContact CG2-CB 4.37Å; K45-G62 WeakPolarHBondContact CE-O 3.21Å; K45-G62 PolarHBondContact NZ-O 3.35Å; K45-F65 HydrophobicContact CB-CB 4.19Å; K45-I84 HydrophobicContact CB-CD1 3.91Å; K45-I84 HydrophobicContact CG-CD1 3.95Å; K45-I84 HydrophobicContact CG-CG2 4.27Å; K45-W150 HydrophobicContact CB-CZ2 4.44Å; K45-W150 HydrophobicContact CD-CZ2 3.9Å; K45-W150 HydrophobicContact CG-CZ2 3.87Å; K45-A155 WeakPolarHBondContact CD-O 3.35Å; K45-A155 WeakPolarHBondContact CE-O 3.44Å; K45-A155 PolarHBondContact NZ-O 2.91Å; K45-R156 PolarHBondContact NZ-O 3.04Å; K45-K158 PolarHBondContact NZ-O 3.04Å; K45-A159 CarbonylContact O-C 3.55Å; K45-A159 WeakPolarHBondContact O-CA 3.45Å; K45-A159 VanDerWaalsContact O-CB 3.32Å; K45-A159 WeakPolarHBondContact O-CB 3.25Å; K45-Q160 HydrophobicContact CB-CB 4.21Å; K45-Q160 HydrophobicContact CD-CB 4.15Å; K45-Q160 HydrophobicContact CD-CG 3.99Å; K45-Q160 PolarHBondContact N-O 3.2Å; K45-Q160 PolarHBondContact O-N 3.19Å; K45-L162 HydrophobicContact CB-CD1 4.39Å
46M96.3Very high88.7Confident2 Ų245.4 Ų45.41%0.0127%0.265CS..PPolyproline II helixtrans-81.4153-174.3-60.9-56.1-63.700111.6Y44 F59 G64 F66 L287 T294 L296Y44-M46 HydrophobicContact CD1-SD 4.26Å; M46-F59 HydrophobicContact CB-CD1 4.24Å; M46-F59 HydrophobicContact CB-CE1 4.33Å; M46-F59 HydrophobicContact CG-CD1 4.14Å; M46-F59 HydrophobicContact CG-CE1 3.78Å; M46-G64 PolarHBondContact N-O 3.36Å; M46-F66 HydrophobicContact CG-CD2 3.79Å; M46-F66 HydrophobicContact CG-CE2 3.84Å; M46-F66 HydrophobicContact SD-CD2 3.74Å; M46-F66 HydrophobicContact SD-CE2 3.97Å; M46-L287 HydrophobicContact SD-CD1 3.75Å; M46-T294 HydrophobicContact CE-CG2 3.55Å; M46-L296 HydrophobicContact CE-CD2 3.43Å; M46-L296 VanDerWaalsContact CE-CD2 3.43Å; M46-L296 HydrophobicContact CE-CG 4.29Å; M46-L296 HydrophobicContact SD-CD2 3.96Å
47A95.9Very high88.6Confident9 Ų939.1 Ų39.17%0.07424%0.241CC..PPolyproline II helixtrans-57.7155.1163.900000110.2Q49 D157 A159A47-Q49 PolarHBondContact O-N 3.17Å; A47-Q49 VanDerWaalsContact O-N 3.12Å; A47-Q49 PolarHBondContact O-NE2 2.75Å; A47-D157 WeakPolarHBondContact CA-O 3.48Å; A47-A159 HydrophobicContact CB-CB 4.35Å
48K94.3Very high88.6Confident106 Ų10639 Ų3946%0.46123%0.233SC..PPolyproline II helixtrans-57121.2174.8-172.5-178.2-177.7-1760109A60 D157K48-A60 WeakPolarHBondContact CE-O 3.26Å; K48-A60 WeakPolarHBondContact CG-O 2.8Å; K48-D157 PolarHBondContact N-O 3.41Å
49Q89.1Confident88.5Confident23 Ų2338.9 Ų38.911%0.10723%0.232CC..PPolyproline II helixtrans-84.3144.2-177.2-60.7-63.1-57.300110A47 V51 F53 F59 A60A47-Q49 PolarHBondContact O-N 3.17Å; A47-Q49 VanDerWaalsContact O-N 3.12Å; A47-Q49 PolarHBondContact O-NE2 2.75Å; Q49-V51 VanDerWaalsContact C-N 3.27Å; Q49-V51 PolarHBondContact O-N 2.96Å; Q49-F53 HydrophobicContact CB-CE2 4.09Å; Q49-F53 HydrophobicContact CG-CE2 3.84Å; Q49-F59 HydrophobicContact CB-CB 4.24Å; Q49-F59 HydrophobicContact CG-CB 3.95Å; Q49-F59 HydrophobicContact CG-CD1 4.36Å; Q49-F59 PolarHBondContact N-O 3.21Å; Q49-A60 WeakPolarHBondContact O-CA 3.46Å
50P82.6Confident88.3Confident124 Ų12439 Ų3981%0.80524%0.236SC*.SBendtrans-69.8-26.2-179.227.2-34.2000112.8
51V75Confident88.1Confident104 Ų10443.3 Ų43.363%0.6326%0.259SS*.SBendtrans-136.3143179.6-171.10000107.8Q49Q49-V51 VanDerWaalsContact C-N 3.27Å; Q49-V51 PolarHBondContact O-N 2.96Å
52D66Low88Confident59 Ų5943.3 Ų43.332%0.31626%0.259SS..  trans-73.5132.6171.3-79.2-56.9000111.3D54 G57 A60D52-D54 VanDerWaalsContact CB-O 3.23Å; D52-D54 WeakPolarHBondContact CB-O 3.09Å; D52-G57 VanDerWaalsContact CG-CA 3.43Å; D52-G57 VanDerWaalsContact OD1-CA 3.25Å; D52-G57 WeakPolarHBondContact OD1-CA 3.32Å; D52-G57 VanDerWaalsContact OD2-CA 3.24Å; D52-G57 WeakPolarHBondContact OD2-CA 3.35Å; D52-A60 HydrophobicContact CB-CB 4.23Å; D52-A60 WeakPolarHBondContact OD1-CB 3.09Å; D52-A60 PolarHBondContact OD1-N 3.09Å; D52-A60 WeakPolarHBondContact OD2-CB 3.4Å
53F66.8Low87.9Confident100 Ų10044.9 Ų44.944%0.43927%0.266SS..SBendtrans-78.5-7.6169.6-58.8-79.8000112.6Q49 F59 T294Q49-F53 HydrophobicContact CB-CE2 4.09Å; Q49-F53 HydrophobicContact CG-CE2 3.84Å; F53-F59 HydrophobicContact CD2-CB 4.47Å; F53-T294 HydrophobicContact CE2-CG2 4.22Å; F53-T294 HydrophobicContact CZ-CG2 4.45Å
54D68.5Low87.8Confident53 Ų5345 Ų4528%0.28327%0.267SS..SBendtrans-151.2162179.257.854000112.2D52 S56 K79D52-D54 VanDerWaalsContact CB-O 3.23Å; D52-D54 WeakPolarHBondContact CB-O 3.09Å; D54-S56 PolarHBondContact O-N 3.22Å; D54-S56 VanDerWaalsContact OD1-CB 3.24Å; D54-S56 WeakPolarHBondContact OD1-CB 3.46Å; D54-S56 PolarHBondContact OD1-N 3.46Å; D54-S56 VanDerWaalsContact OD1-N 3.13Å; D54-S56 PolarHBondContact OD1-OG 3.44Å; D54-K79 WeakPolarHBondContact OD2-CE 3.45Å; D54-K79 IonicContact OD2-NZ 2.83Å; D54-K79 PolarHBondContact OD2-NZ 3.31Å
55A73.7Confident87.7Confident118 Ų11845 Ų4598%0.97527%0.267SS*.THydrogen-bonded Turntrans-65.2-3-176.500000114.6
56S84.1Confident87.7Confident66 Ų6645 Ų4546%0.46227%0.267SS..THydrogen-bonded Turntrans-82.2-18.5-171.278.50000114.3D54 I58D54-S56 PolarHBondContact O-N 3.22Å; D54-S56 VanDerWaalsContact OD1-CB 3.24Å; D54-S56 WeakPolarHBondContact OD1-CB 3.46Å; D54-S56 PolarHBondContact OD1-N 3.46Å; D54-S56 VanDerWaalsContact OD1-N 3.13Å; D54-S56 PolarHBondContact OD1-OG 3.44Å; S56-I58 PolarHBondContact O-N 3.41Å; S56-I58 WeakPolarHBondContact OG-CB 3.44Å; S56-I58 VanDerWaalsContact OG-CD1 3.29Å; S56-I58 WeakPolarHBondContact OG-CD1 3.21Å; S56-I58 WeakPolarHBondContact OG-CG1 3.49Å; S56-I58 PolarHBondContact OG-N 2.81Å
57G90.7Very high87.8Confident10 Ų1045.6 Ų45.610%0.10327%0.269CS..  trans78.7-6-175.300000114.9D52 F59 N61D52-G57 VanDerWaalsContact CG-CA 3.43Å; D52-G57 VanDerWaalsContact OD1-CA 3.25Å; D52-G57 WeakPolarHBondContact OD1-CA 3.32Å; D52-G57 VanDerWaalsContact OD2-CA 3.24Å; D52-G57 WeakPolarHBondContact OD2-CA 3.35Å; G57-F59 PolarHBondContact O-N 2.9Å; G57-N61 WeakPolarHBondContact O-CB 3.12Å; G57-N61 PolarHBondContact O-N 3.05Å; G57-N61 PolarHBondContact O-ND2 3.46Å
58I94.5Very high87.9Confident26 Ų2645.1 Ų45.113%0.13327%0.265CS..THydrogen-bonded Turntrans-64.4-42.3-164.6-73168.1000111.5S56 G62 H63 G64 K81S56-I58 PolarHBondContact O-N 3.41Å; S56-I58 WeakPolarHBondContact OG-CB 3.44Å; S56-I58 VanDerWaalsContact OG-CD1 3.29Å; S56-I58 WeakPolarHBondContact OG-CD1 3.21Å; S56-I58 WeakPolarHBondContact OG-CG1 3.49Å; S56-I58 PolarHBondContact OG-N 2.81Å; I58-G62 PolarHBondContact O-N 2.59Å; I58-H63 HydrophobicContact CG2-CB 4.33Å; I58-H63 CarbonylContact O-C 3.52Å; I58-H63 WeakPolarHBondContact O-CA 3.39Å; I58-H63 PolarHBondContact O-N 3.43Å; I58-G64 VanDerWaalsContact CG2-CA 3.41Å; I58-G64 PolarHBondContact O-N 2.89Å; I58-K81 WeakPolarHBondContact CD1-O 3.36Å
59F93.7Very high88Confident1 Ų140.2 Ų40.20%0.00424%0.244CC..THydrogen-bonded Turntrans-80.8-40.4-175.7-75.7-99.4000111.9M46 Q49 F53 G57 N61 G62 F66 K79M46-F59 HydrophobicContact CB-CD1 4.24Å; M46-F59 HydrophobicContact CB-CE1 4.33Å; M46-F59 HydrophobicContact CG-CD1 4.14Å; M46-F59 HydrophobicContact CG-CE1 3.78Å; Q49-F59 HydrophobicContact CB-CB 4.24Å; Q49-F59 HydrophobicContact CG-CB 3.95Å; Q49-F59 HydrophobicContact CG-CD1 4.36Å; Q49-F59 PolarHBondContact N-O 3.21Å; F53-F59 HydrophobicContact CD2-CB 4.47Å; G57-F59 PolarHBondContact O-N 2.9Å; F59-N61 PolarHBondContact O-N 3.09Å; F59-G62 PolarHBondContact O-N 2.74Å; F59-F66 HydrophobicContact CE1-CD2 4.33Å; F59-F66 AromaticContact CE1-CE2 3.8Å; F59-F66 HydrophobicContact CE1-CE2 3.8Å; F59-F66 HydrophobicContact CZ-CE2 4.28Å; F59-K79 HydrophobicContact CE2-CD 4.22Å; F59-K79 HydrophobicContact CE2-CG 4.06Å; F59-K79 HydrophobicContact CZ-CD 4.15Å; F59-K79 VanDerWaalsContact CZ-CE 3.48Å; F59-K79 HydrophobicContact CZ-CG 3.7Å
60A92.9Very high88.3Confident17 Ų1740.9 Ų40.914%0.1425%0.251CS..THydrogen-bonded Turntrans-69.5-21.9175.300000112.9K48 Q49 D52 G62K48-A60 WeakPolarHBondContact CE-O 3.26Å; K48-A60 WeakPolarHBondContact CG-O 2.8Å; Q49-A60 WeakPolarHBondContact O-CA 3.46Å; D52-A60 HydrophobicContact CB-CB 4.23Å; D52-A60 WeakPolarHBondContact OD1-CB 3.09Å; D52-A60 PolarHBondContact OD1-N 3.09Å; D52-A60 WeakPolarHBondContact OD2-CB 3.4Å; A60-G62 VanDerWaalsContact C-N 3.33Å
61N94.3Very high88.8Confident92 Ų9238.6 Ų38.649%0.49224%0.243SC..THydrogen-bonded Turntrans-86.1-0.7171.2-68.8-46.6000113.8G57 F59G57-N61 WeakPolarHBondContact O-CB 3.12Å; G57-N61 PolarHBondContact O-N 3.05Å; G57-N61 PolarHBondContact O-ND2 3.46Å; F59-N61 PolarHBondContact O-N 3.09Å
62G95.5Very high89.7Confident0 Ų035.4 Ų35.40%022%0.224CC..THydrogen-bonded Turntrans76.925.2177.400000114.3K45 I58 F59 A60 R156K45-G62 WeakPolarHBondContact CE-O 3.21Å; K45-G62 PolarHBondContact NZ-O 3.35Å; I58-G62 PolarHBondContact O-N 2.59Å; F59-G62 PolarHBondContact O-N 2.74Å; A60-G62 VanDerWaalsContact C-N 3.33Å; G62-R156 WeakPolarHBondContact CA-O 3.23Å
63H96.7Very high91.1Very high33 Ų3332.8 Ų32.815%0.15321%0.21CC..  trans-113.2-3177.6-62.2-55.9000113.5I58 G83 I84 D85 W150I58-H63 HydrophobicContact CG2-CB 4.33Å; I58-H63 CarbonylContact O-C 3.52Å; I58-H63 WeakPolarHBondContact O-CA 3.39Å; I58-H63 PolarHBondContact O-N 3.43Å; H63-G83 WeakPolarHBondContact O-CA 3.38Å; H63-I84 HydrophobicContact CB-CG2 4.34Å; H63-I84 PolarHBondContact O-N 2.75Å; H63-D85 WeakPolarHBondContact CB-OD1 3.36Å; H63-D85 IonicContact CD2-OD1 3.66Å; H63-D85 IonicContact CG-OD1 3.43Å; H63-D85 IonicContact ND1-OD1 3.23Å; H63-W150 AromaticContact ND1-CD1 3.88Å
64G96Very high92.4Very high1 Ų132.1 Ų32.11%0.0122%0.223CC..  trans-71.6141.8179.200000113M46 I58M46-G64 PolarHBondContact N-O 3.36Å; I58-G64 VanDerWaalsContact CG2-CA 3.41Å; I58-G64 PolarHBondContact O-N 2.89Å
65F97.3Very high93.7Very high0 Ų036.7 Ų36.70%025%0.245CC..EExtended strand (participates in β ladder)trans-149154178.470.8-87.3000112I43 Y44 K45 Y67 S80 M82 I84 Q89I43-F65 HydrophobicContact CB-CD2 4.45Å; I43-F65 HydrophobicContact CD1-CE2 4.44Å; I43-F65 HydrophobicContact CG1-CD2 4.23Å; I43-F65 HydrophobicContact CG1-CE2 4.29Å; I43-F65 HydrophobicContact CG2-CB 3.83Å; I43-F65 HydrophobicContact CG2-CD2 3.62Å; I43-F65 HydrophobicContact CG2-CE2 4.4Å; I43-F65 HydrophobicContact CG2-CG 3.91Å; Y44-F65 CarbonylContact O-C 3.46Å; Y44-F65 VanDerWaalsContact O-CA 3.25Å; Y44-F65 WeakPolarHBondContact O-CA 3.47Å; Y44-F65 WeakPolarHBondContact O-CB 3.31Å; K45-F65 HydrophobicContact CB-CB 4.19Å; F65-Y67 HydrophobicContact CD2-CD1 4.23Å; F65-Y67 AromaticContact CE2-CD1 3.73Å; F65-Y67 HydrophobicContact CE2-CD1 3.73Å; F65-Y67 HydrophobicContact CE2-CG 4.38Å; F65-S80 WeakPolarHBondContact CE1-OG 3.25Å; F65-S80 WeakPolarHBondContact CZ-OG 3.33Å; F65-S80 WeakPolarHBondContact O-CB 3.42Å; F65-S80 PolarHBondContact O-N 3.28Å; F65-M82 WeakPolarHBondContact CE1-O 3.17Å; F65-I84 HydrophobicContact CD1-CB 3.71Å; F65-I84 HydrophobicContact CD1-CG1 4.31Å; F65-I84 HydrophobicContact CE1-CB 4.03Å; F65-I84 HydrophobicContact CE1-CG1 4.5Å; F65-Q89 HydrophobicContact CE1-CB 4.47Å; F65-Q89 HydrophobicContact CE1-CG 4.35Å; F65-Q89 HydrophobicContact CZ-CB 3.98Å; F65-Q89 HydrophobicContact CZ-CG 4.27Å
66F97.4Very high94.8Very high2 Ų231.9 Ų31.91%0.00921%0.206CC..EExtended strand (participates in β ladder)trans-105.6155.2166.4-66.6-103.1000109I43 Y44 M46 F59 W77 T78 K79 L287 H289I43-F66 WeakPolarHBondContact CA-O 3.48Å; Y44-F66 PolarHBondContact N-O 3.05Å; Y44-F66 PolarHBondContact O-N 3.05Å; M46-F66 HydrophobicContact CG-CD2 3.79Å; M46-F66 HydrophobicContact CG-CE2 3.84Å; M46-F66 HydrophobicContact SD-CD2 3.74Å; M46-F66 HydrophobicContact SD-CE2 3.97Å; F59-F66 HydrophobicContact CE1-CD2 4.33Å; F59-F66 AromaticContact CE1-CE2 3.8Å; F59-F66 HydrophobicContact CE1-CE2 3.8Å; F59-F66 HydrophobicContact CZ-CE2 4.28Å; F66-W77 HydrophobicContact CB-CE3 3.8Å; F66-W77 HydrophobicContact CB-CZ3 4.36Å; F66-W77 HydrophobicContact CD1-CB 4.34Å; F66-T78 CarbonylContact C-O 3.5Å; F66-T78 VanDerWaalsContact CA-O 3.23Å; F66-T78 WeakPolarHBondContact CA-O 3.38Å; F66-K79 HydrophobicContact CD1-CB 3.93Å; F66-K79 HydrophobicContact CD1-CG 4.45Å; F66-K79 HydrophobicContact CE1-CB 3.66Å; F66-K79 HydrophobicContact CE1-CD 4.49Å; F66-K79 HydrophobicContact CE1-CG 3.98Å; F66-K79 HydrophobicContact CZ-CB 4.29Å; F66-K79 HydrophobicContact CZ-CD 4.37Å; F66-K79 HydrophobicContact CZ-CG 4.09Å; F66-L287 HydrophobicContact CB-CD1 3.78Å; F66-L287 HydrophobicContact CD1-CB 4.25Å; F66-L287 HydrophobicContact CD2-CB 4.28Å; F66-L287 HydrophobicContact CD2-CD1 3.64Å; F66-L287 HydrophobicContact CE1-CB 4.3Å; F66-L287 HydrophobicContact CE2-CB 4.33Å; F66-L287 HydrophobicContact CE2-CD1 4.35Å; F66-L287 HydrophobicContact CG-CB 4.24Å; F66-L287 HydrophobicContact CG-CD1 3.75Å; F66-L287 HydrophobicContact CZ-CB 4.34Å; F66-H289 HydrophobicContact CD1-CB 4.28Å; F66-H289 HydrophobicContact CE1-CB 3.79Å
67Y98.1Very high95.4Very high13 Ų1329.2 Ų29.25%0.05119%0.186CC..EExtended strand (participates in β ladder)trans-142.6158.317867.4-94.9000113.5L42 F65 T78 M90L42-Y67 CarbonylContact O-C 3.49Å; L42-Y67 WeakPolarHBondContact O-CA 3.48Å; L42-Y67 WeakPolarHBondContact O-CB 3.44Å; F65-Y67 HydrophobicContact CD2-CD1 4.23Å; F65-Y67 AromaticContact CE2-CD1 3.73Å; F65-Y67 HydrophobicContact CE2-CD1 3.73Å; F65-Y67 HydrophobicContact CE2-CG 4.38Å; Y67-T78 HydrophobicContact CD1-CG2 4.49Å; Y67-T78 WeakPolarHBondContact CD1-O 3.45Å; Y67-T78 HydrophobicContact CE1-CG2 3.69Å; Y67-T78 HydrophobicContact CE2-CG2 4.06Å; Y67-T78 VanDerWaalsContact CZ-CG2 3.44Å; Y67-T78 PolarHBondContact N-O 3.36Å; Y67-T78 PolarHBondContact O-N 3Å; Y67-T78 WeakPolarHBondContact OH-CG2 3.43Å; Y67-M90 HydrophobicContact CD1-SD 4.07Å; Y67-M90 HydrophobicContact CD2-CE 4.09Å; Y67-M90 HydrophobicContact CD2-SD 3.33Å; Y67-M90 WeakPolarHBondContact CD2-SD 3.49Å; Y67-M90 HydrophobicContact CE1-SD 4.47Å; Y67-M90 HydrophobicContact CE2-SD 3.81Å; Y67-M90 HydrophobicContact CG-SD 3.46Å
68L97.9Very high95.7Very high0 Ų029.9 Ų29.90%019%0.189CC..EExtended strand (participates in β ladder)trans-128150.3167.3-66.5168.9000108.3W40 F41 L42 A73 G76 W77 A345 F346W40-L68 HydrophobicContact CZ3-CB 4.06Å; F41-L68 CarbonylContact C-O 3.58Å; F41-L68 VanDerWaalsContact CA-O 3.25Å; F41-L68 WeakPolarHBondContact CA-O 3.23Å; F41-L68 WeakPolarHBondContact CB-O 3.33Å; L42-L68 HydrophobicContact CB-CB 4.47Å; L42-L68 PolarHBondContact N-O 3.15Å; L42-L68 PolarHBondContact O-N 3.28Å; L68-A73 HydrophobicContact CD2-CB 4.43Å; L68-G76 VanDerWaalsContact CD2-O 3.24Å; L68-G76 WeakPolarHBondContact CD2-O 3.35Å; L68-W77 HydrophobicContact CD1-CD2 3.96Å; L68-W77 HydrophobicContact CD1-CE3 4.03Å; L68-W77 HydrophobicContact CD1-CH2 3.84Å; L68-W77 HydrophobicContact CD1-CZ2 3.73Å; L68-W77 HydrophobicContact CD1-CZ3 3.98Å; L68-W77 HydrophobicContact CD2-CD2 4.23Å; L68-W77 HydrophobicContact CD2-CE3 4.34Å; L68-W77 HydrophobicContact CD2-CG 4.41Å; L68-W77 HydrophobicContact CG-CD2 3.86Å; L68-W77 HydrophobicContact CG-CE3 3.64Å; L68-W77 HydrophobicContact CG-CH2 4.25Å; L68-W77 HydrophobicContact CG-CZ2 4.42Å; L68-W77 HydrophobicContact CG-CZ3 3.85Å; L68-A345 HydrophobicContact CD1-CB 3.72Å; L68-A345 HydrophobicContact CD2-CB 3.84Å; L68-A345 HydrophobicContact CG-CB 4.45Å; L68-F346 HydrophobicContact CD1-CD2 4.28Å; L68-F346 HydrophobicContact CD1-CE2 3.97Å
69N96.9Very high95.7Very high3 Ų330.2 Ų30.22%0.01619%0.189CC..EExtended strand (participates in β ladder)trans-148.4164.4168.764.863000111.2V38 W40 F41 A71 T72 A73 M90V38-N69 HydrophobicContact CG1-CB 4.42Å; V38-N69 HydrophobicContact CG2-CB 4.37Å; W40-N69 WeakPolarHBondContact O-CA 3.25Å; F41-N69 HydrophobicContact CB-CB 3.84Å; N69-A71 PolarHBondContact O-N 3.03Å; N69-A71 WeakPolarHBondContact OD1-CA 3.39Å; N69-A71 WeakPolarHBondContact OD1-CB 3.33Å; N69-A71 PolarHBondContact OD1-N 2.83Å; N69-T72 PolarHBondContact ND2-OG1 3.46Å; N69-T72 VanDerWaalsContact ND2-OG1 3.07Å; N69-T72 PolarHBondContact O-N 3.19Å; N69-T72 VanDerWaalsContact O-N 3.14Å; N69-T72 PolarHBondContact OD1-N 2.71Å; N69-T72 PolarHBondContact OD1-OG1 3.01Å; N69-T72 VanDerWaalsContact OD1-OG1 3.13Å; N69-A73 WeakPolarHBondContact O-CB 3.42Å; N69-A73 PolarHBondContact O-N 3.25Å; N69-M90 HydrophobicContact CB-CE 3.77Å
70S95.7Very high95.8Very high36 Ų3630.3 Ų30.325%0.25219%0.19SC..THydrogen-bonded Turntrans-58.9-21.1-176.669.20000114.6Q39 W40Q39-S70 PolarHBondContact N-OG 3.02Å; W40-S70 PolarHBondContact O-N 2.48Å
71A93Very high95.8Very high76 Ų7638.5 Ų38.563%0.62822%0.222SC*.THydrogen-bonded Turntrans-87.5-31.2179.500000113.1V38 N69V38-A71 HydrophobicContact CG1-CB 4.36Å; N69-A71 PolarHBondContact O-N 3.03Å; N69-A71 WeakPolarHBondContact OD1-CA 3.39Å; N69-A71 WeakPolarHBondContact OD1-CB 3.33Å; N69-A71 PolarHBondContact OD1-N 2.83Å
72T93.8Very high95.8Very high38 Ų3836.6 Ų36.623%0.23321%0.211CC..THydrogen-bonded Turntrans-122.1-2.2-171.162.50000115N69 A74 M75N69-T72 PolarHBondContact ND2-OG1 3.46Å; N69-T72 VanDerWaalsContact ND2-OG1 3.07Å; N69-T72 PolarHBondContact O-N 3.19Å; N69-T72 VanDerWaalsContact O-N 3.14Å; N69-T72 PolarHBondContact OD1-N 2.71Å; N69-T72 PolarHBondContact OD1-OG1 3.01Å; N69-T72 VanDerWaalsContact OD1-OG1 3.13Å; T72-A74 PolarHBondContact O-N 3.4Å; T72-M75 VanDerWaalsContact CB-CE 3.45Å; T72-M75 HydrophobicContact CG2-CE 3.62Å; T72-M75 WeakPolarHBondContact O-CB 3.29Å; T72-M75 PolarHBondContact O-N 2.79Å
73A95.4Very high95.8Very high4 Ų436.7 Ų36.73%0.03321%0.212CC..G310 helixtrans-57.5-24.5-174.900000114.8W40 L68 N69 M75 G76 P341W40-A73 HydrophobicContact CH2-CB 3.52Å; W40-A73 HydrophobicContact CZ2-CB 4.17Å; W40-A73 HydrophobicContact CZ3-CB 4.45Å; L68-A73 HydrophobicContact CD2-CB 4.43Å; N69-A73 WeakPolarHBondContact O-CB 3.42Å; N69-A73 PolarHBondContact O-N 3.25Å; A73-M75 PolarHBondContact O-N 3Å; A73-G76 PolarHBondContact O-N 2.88Å; A73-P341 HydrophobicContact CB-CB 3.91Å
74A94.9Very high95.9Very high86 Ų8635.1 Ų35.171%0.71120%0.204SC*.G310 helixtrans-62.2-22174.600000113.4T72 G76 P341T72-A74 PolarHBondContact O-N 3.4Å; A74-G76 VanDerWaalsContact C-N 3.31Å; A74-P341 HydrophobicContact CB-CB 4.44Å
75M95.3Very high96Very high148 Ų14836.9 Ų36.973%0.72921%0.214SC*.G310 helixtrans-85-4.1175.1-58.8-171.6-68.700113T72 A73T72-M75 VanDerWaalsContact CB-CE 3.45Å; T72-M75 HydrophobicContact CG2-CE 3.62Å; T72-M75 WeakPolarHBondContact O-CB 3.29Å; T72-M75 PolarHBondContact O-N 2.79Å; A73-M75 PolarHBondContact O-N 3Å
76G96.5Very high96Very high17 Ų1742 Ų4218%0.17524%0.236CC..  trans78.4-165.1-174.700000113.3L68 A73 A74L68-G76 VanDerWaalsContact CD2-O 3.24Å; L68-G76 WeakPolarHBondContact CD2-O 3.35Å; A73-G76 PolarHBondContact O-N 2.88Å; A74-G76 VanDerWaalsContact C-N 3.31Å
77W97.4Very high95.9Very high10 Ų1045.5 Ų45.54%0.03826%0.259CS..  trans-60.9135.1-176.3-71.1104000112L42 Y44 F66 L68 L287 H289 A345 F346 T349L42-W77 HydrophobicContact CD2-CH2 3.38Å; L42-W77 HydrophobicContact CD2-CZ3 3.7Å; Y44-W77 AromaticContact CD2-CH2 3.85Å; Y44-W77 HydrophobicContact CD2-CH2 3.85Å; Y44-W77 HydrophobicContact CD2-CZ2 4.33Å; Y44-W77 HydrophobicContact CG-CH2 4.42Å; F66-W77 HydrophobicContact CB-CE3 3.8Å; F66-W77 HydrophobicContact CB-CZ3 4.36Å; F66-W77 HydrophobicContact CD1-CB 4.34Å; L68-W77 HydrophobicContact CD1-CD2 3.96Å; L68-W77 HydrophobicContact CD1-CE3 4.03Å; L68-W77 HydrophobicContact CD1-CH2 3.84Å; L68-W77 HydrophobicContact CD1-CZ2 3.73Å; L68-W77 HydrophobicContact CD1-CZ3 3.98Å; L68-W77 HydrophobicContact CD2-CD2 4.23Å; L68-W77 HydrophobicContact CD2-CE3 4.34Å; L68-W77 HydrophobicContact CD2-CG 4.41Å; L68-W77 HydrophobicContact CG-CD2 3.86Å; L68-W77 HydrophobicContact CG-CE3 3.64Å; L68-W77 HydrophobicContact CG-CH2 4.25Å; L68-W77 HydrophobicContact CG-CZ2 4.42Å; L68-W77 HydrophobicContact CG-CZ3 3.85Å; W77-L287 HydrophobicContact CD2-CD2 3.94Å; W77-L287 HydrophobicContact CG-CD2 4.13Å; W77-L287 HydrophobicContact CZ2-CD2 3.93Å; W77-H289 PolarHBondContact O-ND1 3.07Å; W77-A345 PolarHBondContact NE1-O 2.93Å; W77-F346 AromaticContact CH2-CE2 3.84Å; W77-F346 HydrophobicContact CH2-CE2 3.84Å; W77-F346 AromaticContact CH2-CZ 3.73Å; W77-F346 HydrophobicContact CH2-CZ 3.73Å; W77-F346 AromaticContact CZ2-CD2 3.97Å; W77-F346 HydrophobicContact CZ2-CD2 3.97Å; W77-F346 HydrophobicContact CZ2-CE1 4.03Å; W77-F346 AromaticContact CZ2-CE2 3.43Å; W77-F346 HydrophobicContact CZ2-CE2 3.43Å; W77-F346 VanDerWaalsContact CZ2-CE2 3.43Å; W77-F346 HydrophobicContact CZ2-CG 4.48Å; W77-F346 AromaticContact CZ2-CZ 3.47Å; W77-F346 HydrophobicContact CZ2-CZ 3.47Å; W77-F346 VanDerWaalsContact CZ2-CZ 3.47Å; W77-T349 PolarHBondContact NE1-OG1 2.67Å; W77-T349 VanDerWaalsContact NE1-OG1 3.14Å
78T96.2Very high95.7Very high25 Ų2551 Ų5115%0.15328%0.283CS..EExtended strand (participates in β ladder)trans-109.6123.6173.7-57.70000110.5F66 Y67 H289F66-T78 CarbonylContact C-O 3.5Å; F66-T78 VanDerWaalsContact CA-O 3.23Å; F66-T78 WeakPolarHBondContact CA-O 3.38Å; Y67-T78 HydrophobicContact CD1-CG2 4.49Å; Y67-T78 WeakPolarHBondContact CD1-O 3.45Å; Y67-T78 HydrophobicContact CE1-CG2 3.69Å; Y67-T78 HydrophobicContact CE2-CG2 4.06Å; Y67-T78 VanDerWaalsContact CZ-CG2 3.44Å; Y67-T78 PolarHBondContact N-O 3.36Å; Y67-T78 PolarHBondContact O-N 3Å; Y67-T78 WeakPolarHBondContact OH-CG2 3.43Å; T78-H289 WeakPolarHBondContact CA-ND1 3.41Å
79K94.8Very high95.6Very high32 Ų3251 Ų5114%0.13928%0.283CS..EExtended strand (participates in β ladder)trans-74124.3172.1-171.8-178.1171.1-170.50109.1D54 F59 F66 H289D54-K79 WeakPolarHBondContact OD2-CE 3.45Å; D54-K79 IonicContact OD2-NZ 2.83Å; D54-K79 PolarHBondContact OD2-NZ 3.31Å; F59-K79 HydrophobicContact CE2-CD 4.22Å; F59-K79 HydrophobicContact CE2-CG 4.06Å; F59-K79 HydrophobicContact CZ-CD 4.15Å; F59-K79 VanDerWaalsContact CZ-CE 3.48Å; F59-K79 HydrophobicContact CZ-CG 3.7Å; F66-K79 HydrophobicContact CD1-CB 3.93Å; F66-K79 HydrophobicContact CD1-CG 4.45Å; F66-K79 HydrophobicContact CE1-CB 3.66Å; F66-K79 HydrophobicContact CE1-CD 4.49Å; F66-K79 HydrophobicContact CE1-CG 3.98Å; F66-K79 HydrophobicContact CZ-CB 4.29Å; F66-K79 HydrophobicContact CZ-CD 4.37Å; F66-K79 HydrophobicContact CZ-CG 4.09Å; K79-H289 HydrophobicContact CB-CB 4Å
80S95.1Very high95.6Very high3 Ų350.9 Ų50.92%0.02128%0.282CS..  trans-73.2140.5177.8-173.40000112.1Q32 F65 M82Q32-S80 PolarHBondContact NE2-OG 3.3Å; Q32-S80 PolarHBondContact OE1-OG 2.86Å; Q32-S80 VanDerWaalsContact OE1-OG 3.11Å; F65-S80 WeakPolarHBondContact CE1-OG 3.25Å; F65-S80 WeakPolarHBondContact CZ-OG 3.33Å; F65-S80 WeakPolarHBondContact O-CB 3.42Å; F65-S80 PolarHBondContact O-N 3.28Å; S80-M82 VanDerWaalsContact C-N 3.33Å; S80-M82 PolarHBondContact OG-N 3.03Å; S80-M82 VanDerWaalsContact OG-N 3.08Å; S80-M82 PolarHBondContact OG-O 2.79Å
81K92.9Very high95.7Very high190 Ų19049.1 Ų49.183%0.82627%0.27SS*.SBendtrans-86.5-4.3170-61.3-179.6-178176.30113I58I58-K81 WeakPolarHBondContact CD1-O 3.36Å
82M94.8Very high96Very high52 Ų5246.5 Ų46.526%0.25625%0.245SC..SBendtrans-117.6141.8179.2-60.3-176.3-136.100109.1Q32 F65 S80 K88 Q89Q32-M82 HydrophobicContact CG-CE 3.81Å; F65-M82 WeakPolarHBondContact CE1-O 3.17Å; S80-M82 VanDerWaalsContact C-N 3.33Å; S80-M82 PolarHBondContact OG-N 3.03Å; S80-M82 VanDerWaalsContact OG-N 3.08Å; S80-M82 PolarHBondContact OG-O 2.79Å; M82-K88 HydrophobicContact CE-CB 4.42Å; M82-K88 HydrophobicContact SD-CB 3.94Å; M82-Q89 HydrophobicContact CB-CB 4.23Å; M82-Q89 HydrophobicContact SD-CB 4.35Å
83G96.6Very high96.1Very high1 Ų146 Ų461%0.0124%0.239CC..  trans-66.9147.4170.600000110.9H63 D85 K86H63-G83 WeakPolarHBondContact O-CA 3.38Å; G83-D85 WeakPolarHBondContact CA-OD1 3.21Å; G83-D85 PolarHBondContact O-N 3.2Å; G83-D85 VanDerWaalsContact O-N 3.15Å; G83-K86 WeakPolarHBondContact O-CB 3.34Å; G83-K86 PolarHBondContact O-N 3.03Å
84I98.2Very high96.3Very high0 Ų045.9 Ų45.90%024%0.237CC..THydrogen-bonded Turntrans-61.5-21.2177.2-162165.3000112.1I43 K45 H63 F65 K86 Q89 L91 Y148 W150 L162I43-I84 HydrophobicContact CG2-CD1 3.93Å; K45-I84 HydrophobicContact CB-CD1 3.91Å; K45-I84 HydrophobicContact CG-CD1 3.95Å; K45-I84 HydrophobicContact CG-CG2 4.27Å; H63-I84 HydrophobicContact CB-CG2 4.34Å; H63-I84 PolarHBondContact O-N 2.75Å; F65-I84 HydrophobicContact CD1-CB 3.71Å; F65-I84 HydrophobicContact CD1-CG1 4.31Å; F65-I84 HydrophobicContact CE1-CB 4.03Å; F65-I84 HydrophobicContact CE1-CG1 4.5Å; I84-K86 VanDerWaalsContact C-N 3.31Å; I84-Q89 PolarHBondContact O-NE2 2.87Å; I84-L91 HydrophobicContact CD1-CD2 3.95Å; I84-L91 HydrophobicContact CG1-CD2 3.91Å; I84-Y148 WeakPolarHBondContact O-CE1 3.44Å; I84-Y148 PolarHBondContact O-OH 3.39Å; I84-W150 HydrophobicContact CB-CD2 4.49Å; I84-W150 HydrophobicContact CB-CE3 4.44Å; I84-W150 HydrophobicContact CD1-CD2 4.28Å; I84-W150 HydrophobicContact CD1-CE3 3.77Å; I84-W150 HydrophobicContact CD1-CH2 3.64Å; I84-W150 HydrophobicContact CD1-CZ2 4.14Å; I84-W150 HydrophobicContact CD1-CZ3 3.43Å; I84-W150 VanDerWaalsContact CD1-CZ3 3.43Å; I84-W150 HydrophobicContact CG1-CD2 4.28Å; I84-W150 HydrophobicContact CG1-CE3 3.76Å; I84-W150 HydrophobicContact CG1-CZ3 3.92Å; I84-W150 HydrophobicContact CG2-CB 4.12Å; I84-W150 HydrophobicContact CG2-CD2 3.49Å; I84-W150 VanDerWaalsContact CG2-CD2 3.49Å; I84-W150 HydrophobicContact CG2-CE3 3.89Å; I84-W150 HydrophobicContact CG2-CG 3.59Å; I84-L162 HydrophobicContact CD1-CD1 4.24Å
85D97.5Very high96.4Very high39 Ų3941.8 Ų41.821%0.20920%0.204CC..THydrogen-bonded Turntrans-78-11.9174.568.9-53.1000113.6H63 G83 W150H63-D85 WeakPolarHBondContact CB-OD1 3.36Å; H63-D85 IonicContact CD2-OD1 3.66Å; H63-D85 IonicContact CG-OD1 3.43Å; H63-D85 IonicContact ND1-OD1 3.23Å; G83-D85 WeakPolarHBondContact CA-OD1 3.21Å; G83-D85 PolarHBondContact O-N 3.2Å; G83-D85 VanDerWaalsContact O-N 3.15Å; D85-W150 HydrophobicContact CB-CB 3.8Å
86K97.1Very high96.5Very high107 Ų10736.3 Ų36.347%0.46518%0.175SC..SBendtrans-90.9156.7-174.9-59.4-50.2-176.1-148.50112.6G83 I84 Q89G83-K86 WeakPolarHBondContact O-CB 3.34Å; G83-K86 PolarHBondContact O-N 3.03Å; I84-K86 VanDerWaalsContact C-N 3.31Å; K86-Q89 WeakPolarHBondContact O-CG 3.45Å; K86-Q89 PolarHBondContact O-NE2 3.12Å
87P95Very high96.4Very high76 Ų7635.6 Ų35.649%0.49417%0.167SC..THydrogen-bonded Turntrans-69.8170.3168.731.9-37.1000111.4Q89 E92P87-Q89 PolarHBondContact O-N 2.85Å; P87-E92 WeakPolarHBondContact CA-OE2 3.44Å; P87-E92 HydrophobicContact CB-CG 4.46Å
88K94.4Very high96.3Very high128 Ų12835.9 Ų35.956%0.55717%0.169SC*.THydrogen-bonded Turntrans70.20.6174.7-54178.1-179.21780115.8M82 E92 R93M82-K88 HydrophobicContact CE-CB 4.42Å; M82-K88 HydrophobicContact SD-CB 3.94Å; K88-E92 PolarHBondContact N-OE2 3.19Å; K88-R93 VanDerWaalsContact O-CZ 3.29Å; K88-R93 PolarHBondContact O-NE 2.82Å; K88-R93 PolarHBondContact O-NH2 3.19Å
89Q96.7Very high96.3Very high0 Ų036.5 Ų36.50%017%0.168CC..SBendtrans-91.7168166.359.369.928.600112.1Q32 F65 M82 I84 K86 P87 L91 E92 R93 Y148Q32-Q89 HydrophobicContact CG-CB 4.48Å; Q32-Q89 VanDerWaalsContact OE1-CB 3.28Å; F65-Q89 HydrophobicContact CE1-CB 4.47Å; F65-Q89 HydrophobicContact CE1-CG 4.35Å; F65-Q89 HydrophobicContact CZ-CB 3.98Å; F65-Q89 HydrophobicContact CZ-CG 4.27Å; M82-Q89 HydrophobicContact CB-CB 4.23Å; M82-Q89 HydrophobicContact SD-CB 4.35Å; I84-Q89 PolarHBondContact O-NE2 2.87Å; K86-Q89 WeakPolarHBondContact O-CG 3.45Å; K86-Q89 PolarHBondContact O-NE2 3.12Å; P87-Q89 PolarHBondContact O-N 2.85Å; Q89-L91 PolarHBondContact O-N 2.67Å; Q89-L91 VanDerWaalsContact OE1-CB 3.24Å; Q89-E92 VanDerWaalsContact NE2-CB 3.33Å; Q89-E92 PolarHBondContact O-N 2.92Å; Q89-R93 WeakPolarHBondContact O-CB 3.44Å; Q89-R93 VanDerWaalsContact O-CG 3.25Å; Q89-R93 WeakPolarHBondContact O-CG 3.38Å; Q89-R93 PolarHBondContact O-N 2.93Å; Q89-Y148 PolarHBondContact NE2-OH 2.96Å
90M96.8Very high96.3Very high0 Ų040.2 Ų40.20%019%0.186CC..Hα-helixtrans-53-46.4-168.3-58.3178.972.700114.2R30 E31 Q32 F41 I43 Y67 N69 T94R30-M90 WeakPolarHBondContact O-CA 2.93Å; R30-M90 VanDerWaalsContact O-CB 3.25Å; R30-M90 WeakPolarHBondContact O-CB 3.04Å; E31-M90 HydrophobicContact CB-CE 4.25Å; Q32-M90 HydrophobicContact CB-CG 3.69Å; Q32-M90 HydrophobicContact CB-SD 4.45Å; F41-M90 HydrophobicContact CB-CE 3.29Å; F41-M90 HydrophobicContact CD1-CE 4.02Å; F41-M90 HydrophobicContact CD2-CE 4.31Å; F41-M90 HydrophobicContact CG-CE 3.65Å; I43-M90 HydrophobicContact CD1-CB 4.28Å; Y67-M90 HydrophobicContact CD1-SD 4.07Å; Y67-M90 HydrophobicContact CD2-CE 4.09Å; Y67-M90 HydrophobicContact CD2-SD 3.33Å; Y67-M90 WeakPolarHBondContact CD2-SD 3.49Å; Y67-M90 HydrophobicContact CE1-SD 4.47Å; Y67-M90 HydrophobicContact CE2-SD 3.81Å; Y67-M90 HydrophobicContact CG-SD 3.46Å; N69-M90 HydrophobicContact CB-CE 3.77Å; M90-T94 WeakPolarHBondContact O-CB 3.5Å; M90-T94 PolarHBondContact O-N 2.68Å; M90-T94 PolarHBondContact O-OG1 3.29Å
91L98.2Very high96.2Very high0 Ų045.5 Ų45.50%021%0.209CC..Hα-helixtrans-70.2-45.9-176.3-172.360.4000111.8F41 I43 I84 Q89 T94 L95 L135 F142 Y148 W150 L162F41-L91 HydrophobicContact CZ-CD1 4.44Å; I43-L91 HydrophobicContact CD1-CB 3.8Å; I84-L91 HydrophobicContact CD1-CD2 3.95Å; I84-L91 HydrophobicContact CG1-CD2 3.91Å; Q89-L91 PolarHBondContact O-N 2.67Å; Q89-L91 VanDerWaalsContact OE1-CB 3.24Å; L91-T94 PolarHBondContact O-N 2.9Å; L91-L95 HydrophobicContact CD1-CD1 4.2Å; L91-L95 HydrophobicContact CG-CD1 4.28Å; L91-L95 PolarHBondContact O-N 2.71Å; L91-L135 HydrophobicContact CD1-CD1 4.23Å; L91-L135 HydrophobicContact CD1-CD2 3.77Å; L91-F142 HydrophobicContact CD1-CE1 4.02Å; L91-F142 HydrophobicContact CD1-CZ 3.9Å; L91-F142 HydrophobicContact CD2-CE1 3.87Å; L91-F142 HydrophobicContact CD2-CE2 4.04Å; L91-F142 HydrophobicContact CD2-CZ 3.36Å; L91-F142 HydrophobicContact CG-CE1 4.21Å; L91-F142 HydrophobicContact CG-CZ 3.63Å; L91-Y148 HydrophobicContact CG-CE2 4.35Å; L91-W150 HydrophobicContact CD2-CE3 4.31Å; L91-W150 HydrophobicContact CD2-CZ3 3.78Å; L91-L162 HydrophobicContact CD1-CD2 3.99Å; L91-L162 HydrophobicContact CD2-CD2 3.64Å; L91-L162 HydrophobicContact CG-CD2 4.48Å
92E97.8Very high96Very high20 Ų2040.3 Ų40.39%0.09319%0.194CC..Hα-helixtrans-64.3-44.9175.7-175.9-86.1143.800110.6P87 K88 Q89 T94 L95 R96 Y148P87-E92 WeakPolarHBondContact CA-OE2 3.44Å; P87-E92 HydrophobicContact CB-CG 4.46Å; K88-E92 PolarHBondContact N-OE2 3.19Å; Q89-E92 VanDerWaalsContact NE2-CB 3.33Å; Q89-E92 PolarHBondContact O-N 2.92Å; E92-T94 VanDerWaalsContact C-N 3.25Å; E92-T94 PolarHBondContact O-N 3.26Å; E92-L95 CarbonylContact O-C 3.55Å; E92-L95 PolarHBondContact O-N 3.2Å; E92-R96 WeakPolarHBondContact O-CB 3.41Å; E92-R96 PolarHBondContact O-N 3.14Å; E92-R96 IonicContact OE1-CZ 3.57Å; E92-R96 IonicContact OE1-NE 2.82Å; E92-R96 PolarHBondContact OE1-NE 3.13Å; E92-R96 IonicContact OE1-NH2 3.45Å; E92-R96 PolarHBondContact OE1-NH2 3.07Å; E92-R96 IonicContact OE2-CZ 3.57Å; E92-R96 IonicContact OE2-NE 3.61Å; E92-R96 IonicContact OE2-NH2 2.69Å; E92-R96 PolarHBondContact OE2-NH2 2.82Å; E92-Y148 HydrophobicContact CB-CD1 3.98Å; E92-Y148 HydrophobicContact CB-CD2 3.99Å; E92-Y148 HydrophobicContact CB-CE1 3.74Å; E92-Y148 HydrophobicContact CB-CE2 3.75Å; E92-Y148 HydrophobicContact CB-CG 4.11Å; E92-Y148 HydrophobicContact CG-CD1 3.73Å; E92-Y148 HydrophobicContact CG-CD2 3.96Å; E92-Y148 HydrophobicContact CG-CE1 4.03Å; E92-Y148 HydrophobicContact CG-CE2 4.24Å; E92-Y148 HydrophobicContact CG-CG 3.7Å
93R97.3Very high95.9Very high29 Ų2944.3 Ų44.311%0.10921%0.213CC..Hα-helixtrans-55.3-41.6175.2-75.6174.5-179.2-59.61.6112.6R30 E31 Q32 N35 K88 Q89 R96R30-R93 HydrophobicContact CB-CB 3.85Å; R30-R93 WeakPolarHBondContact CD-O 3.29Å; E31-R93 VanDerWaalsContact O-CD 3.31Å; E31-R93 WeakPolarHBondContact O-CD 3.21Å; Q32-R93 PolarHBondContact O-NE 2.79Å; Q32-R93 PolarHBondContact O-NH2 3.05Å; N35-R93 VanDerWaalsContact CB-NH1 3.33Å; N35-R93 WeakPolarHBondContact OD1-CD 3.42Å; N35-R93 VanDerWaalsContact OD1-CG 3.31Å; N35-R93 WeakPolarHBondContact OD1-CG 3.35Å; N35-R93 PolarHBondContact OD1-NH1 2.88Å; K88-R93 VanDerWaalsContact O-CZ 3.29Å; K88-R93 PolarHBondContact O-NE 2.82Å; K88-R93 PolarHBondContact O-NH2 3.19Å; Q89-R93 WeakPolarHBondContact O-CB 3.44Å; Q89-R93 VanDerWaalsContact O-CG 3.25Å; Q89-R93 WeakPolarHBondContact O-CG 3.38Å; Q89-R93 PolarHBondContact O-N 2.93Å; R93-R96 VanDerWaalsContact CG-NH2 3.28Å
94T98.1Very high95.6Very high0 Ų045.4 Ų45.40%022%0.218CC..Hα-helixtrans-68.5-40.8-179.6-60.30000111.6R30 F41 M90 L91 E92 P97 F133R30-T94 PolarHBondContact N-OG1 2.84Å; F41-T94 HydrophobicContact CE1-CG2 4.33Å; F41-T94 VanDerWaalsContact CE1-OG1 3.3Å; F41-T94 WeakPolarHBondContact CE1-OG1 3.33Å; M90-T94 WeakPolarHBondContact O-CB 3.5Å; M90-T94 PolarHBondContact O-N 2.68Å; M90-T94 PolarHBondContact O-OG1 3.29Å; L91-T94 PolarHBondContact O-N 2.9Å; E92-T94 VanDerWaalsContact C-N 3.25Å; E92-T94 PolarHBondContact O-N 3.26Å; T94-P97 WeakPolarHBondContact O-CD 3.4Å; T94-F133 HydrophobicContact CG2-CD1 3.87Å; T94-F133 HydrophobicContact CG2-CD2 4.2Å; T94-F133 HydrophobicContact CG2-CE1 3.76Å; T94-F133 HydrophobicContact CG2-CE2 4.17Å; T94-F133 HydrophobicContact CG2-CG 4.09Å; T94-F133 HydrophobicContact CG2-CZ 3.95Å; T94-F133 VanDerWaalsContact O-CE1 3.29Å; T94-F133 WeakPolarHBondContact O-CE1 3.47Å
95L97.7Very high95.2Very high0 Ų050.6 Ų50.60%024%0.238CC..Hα-helixtrans-86.4-12.3-179.9-67.9167.8000113.8L91 E92 Y98 Y99 V124 F133 F142 P143 Y148L91-L95 HydrophobicContact CD1-CD1 4.2Å; L91-L95 HydrophobicContact CG-CD1 4.28Å; L91-L95 PolarHBondContact O-N 2.71Å; E92-L95 CarbonylContact O-C 3.55Å; E92-L95 PolarHBondContact O-N 3.2Å; L95-Y98 WeakPolarHBondContact O-CB 3.45Å; L95-Y98 PolarHBondContact O-N 2.71Å; L95-Y99 HydrophobicContact CB-CD2 4.1Å; L95-Y99 HydrophobicContact CB-CE2 3.76Å; L95-Y99 WeakPolarHBondContact O-CD2 3.47Å; L95-Y99 PolarHBondContact O-N 3.38Å; L95-V124 HydrophobicContact CD2-CG1 4.15Å; L95-F133 HydrophobicContact CD2-CE2 4.47Å; L95-F133 HydrophobicContact CD2-CZ 4.03Å; L95-F142 HydrophobicContact CD1-CE1 4Å; L95-F142 HydrophobicContact CD1-CE2 4.22Å; L95-F142 HydrophobicContact CD1-CZ 3.38Å; L95-P143 HydrophobicContact CD1-CB 3.95Å; L95-Y148 HydrophobicContact CD1-CD2 4.32Å; L95-Y148 HydrophobicContact CD1-CE2 4.1Å
96R96.6Very high94.9Very high33 Ų3354.5 Ų54.513%0.12526%0.259CS..Hα-helixtrans-51.1-43.5-178.2-167.6-179.1-57.1144.8-0.9114.6E92 R93 Y98 Y99 E100E92-R96 WeakPolarHBondContact O-CB 3.41Å; E92-R96 PolarHBondContact O-N 3.14Å; E92-R96 IonicContact OE1-CZ 3.57Å; E92-R96 IonicContact OE1-NE 2.82Å; E92-R96 PolarHBondContact OE1-NE 3.13Å; E92-R96 IonicContact OE1-NH2 3.45Å; E92-R96 PolarHBondContact OE1-NH2 3.07Å; E92-R96 IonicContact OE2-CZ 3.57Å; E92-R96 IonicContact OE2-NE 3.61Å; E92-R96 IonicContact OE2-NH2 2.69Å; E92-R96 PolarHBondContact OE2-NH2 2.82Å; R93-R96 VanDerWaalsContact CG-NH2 3.28Å; R96-Y98 PolarHBondContact O-N 2.95Å; R96-Y98 VanDerWaalsContact O-N 3.17Å; R96-Y99 PolarHBondContact O-N 2.71Å; R96-E100 WeakPolarHBondContact CD-OE1 3.26Å; R96-E100 HydrophobicContact CG-CG 3.76Å; R96-E100 WeakPolarHBondContact CG-OE1 3.35Å; R96-E100 PolarHBondContact O-N 3.19Å
97P95.2Very high94.8Very high3 Ų349.8 Ų49.82%0.01924%0.239CC..Hα-helixtrans-57.3-33.8178.9-19.929.4000113.2T25 Y27 T94 K101T25-P97 WeakPolarHBondContact O-CB 3.34Å; T25-P97 WeakPolarHBondContact O-CG 3.4Å; Y27-P97 HydrophobicContact CD1-CB 4.1Å; Y27-P97 HydrophobicContact CD1-CG 4.36Å; Y27-P97 HydrophobicContact CE1-CB 3.77Å; Y27-P97 HydrophobicContact CE1-CG 4.47Å; T94-P97 WeakPolarHBondContact O-CD 3.4Å; P97-K101 PolarHBondContact O-N 2.79Å
98Y95.7Very high94.9Very high16 Ų1646.1 Ų46.16%0.06322%0.216CC..Hα-helixtrans-67.6-44175.7166.3-102.5000112L95 R96 M111 M126 K145 L188L95-Y98 WeakPolarHBondContact O-CB 3.45Å; L95-Y98 PolarHBondContact O-N 2.71Å; R96-Y98 PolarHBondContact O-N 2.95Å; R96-Y98 VanDerWaalsContact O-N 3.17Å; Y98-M111 HydrophobicContact CD1-CE 4.25Å; Y98-M111 HydrophobicContact CE1-CE 3.67Å; Y98-M111 HydrophobicContact CE2-CE 3.98Å; Y98-M126 HydrophobicContact CD2-CE 3.87Å; Y98-M126 HydrophobicContact CD2-SD 4.24Å; Y98-M126 HydrophobicContact CE2-CE 4.24Å; Y98-M126 HydrophobicContact CG-CE 4.26Å; Y98-K145 PolarHBondContact OH-O 2.94Å; Y98-L188 WeakPolarHBondContact OH-CD1 3.24Å
99Y96.1Very high95.1Very high37 Ų3740.4 Ų40.415%0.14519%0.19CC..Hα-helixtrans-77.2-31.5-177.5-68.2-64.2000114.2L95 R96 K101 P143 P144 R146 T147 Y148L95-Y99 HydrophobicContact CB-CD2 4.1Å; L95-Y99 HydrophobicContact CB-CE2 3.76Å; L95-Y99 WeakPolarHBondContact O-CD2 3.47Å; L95-Y99 PolarHBondContact O-N 3.38Å; R96-Y99 PolarHBondContact O-N 2.71Å; Y99-K101 VanDerWaalsContact C-N 3.33Å; Y99-P143 WeakPolarHBondContact OH-CB 3.29Å; Y99-P144 WeakPolarHBondContact CE1-O 3.45Å; Y99-P144 PolarHBondContact OH-O 3.19Å; Y99-R146 WeakPolarHBondContact CD1-O 3.4Å; Y99-T147 VanDerWaalsContact CE1-C 3.43Å; Y99-Y148 HydrophobicContact CD2-CD2 4.48Å; Y99-Y148 AromaticContact CE2-CD2 3.82Å; Y99-Y148 HydrophobicContact CE2-CD2 3.82Å; Y99-Y148 HydrophobicContact CE2-CG 4.31Å
100E94.8Very high95.1Very high110 Ų11040.4 Ų40.451%0.51419%0.19SC..Hα-helixtrans-76.6-22.2179.3-74.1-179.716000112.9R96 P102R96-E100 WeakPolarHBondContact CD-OE1 3.26Å; R96-E100 HydrophobicContact CG-CG 3.76Å; R96-E100 WeakPolarHBondContact CG-OE1 3.35Å; R96-E100 PolarHBondContact O-N 3.19Å; E100-P102 VanDerWaalsContact C-CD 3.47Å
101K92.7Very high95.2Very high114 Ų11440.4 Ų40.450%0.49619%0.19SC..  trans-12665.3-179.1-57.7-178.4-178.81780111.1P97 Y99 E103 D104 R109P97-K101 PolarHBondContact O-N 2.79Å; Y99-K101 VanDerWaalsContact C-N 3.33Å; K101-E103 PolarHBondContact O-N 3.04Å; K101-D104 HydrophobicContact CB-CB 3.7Å; K101-D104 HydrophobicContact CD-CB 4.44Å; K101-D104 PolarHBondContact O-N 3.07Å; K101-D104 VanDerWaalsContact O-N 3.09Å; K101-R109 VanDerWaalsContact O-CZ 3.3Å; K101-R109 PolarHBondContact O-NH1 2.95Å; K101-R109 PolarHBondContact O-NH2 2.89Å
102P89.7Confident95.1Very high81 Ų8140.5 Ų40.553%0.52619%0.191SC..THydrogen-bonded Turntrans-61.1-31-179.125.1-33.9000112.6E100 R105 R109E100-P102 VanDerWaalsContact C-CD 3.47Å; P102-R105 PolarHBondContact O-NH1 2.83Å; P102-R105 VanDerWaalsContact O-NH1 3.09Å; P102-R109 PolarHBondContact O-NH1 3.03Å
103E91.1Very high95.1Very high137 Ų13740 Ų4064%0.6419%0.189SC*.THydrogen-bonded Turntrans-88.54.2178.5-56.9-51.3152.600114.6K101 R105K101-E103 PolarHBondContact O-N 3.04Å; E103-R105 VanDerWaalsContact C-NH1 3.32Å; E103-R105 WeakPolarHBondContact O-CG 3.41Å; E103-R105 PolarHBondContact O-N 3.49Å; E103-R105 PolarHBondContact O-NH1 2.04Å; E103-R105 IonicContact OE2-CZ 2.88Å; E103-R105 IonicContact OE2-NH1 3.68Å; E103-R105 IonicContact OE2-NH2 3.78Å; E103-R105 PolarHBondContact OE2-NH2 3.43Å
104D91.1Very high94.8Very high24 Ų2439.2 Ų39.213%0.12819%0.187CC..  trans-69.5132.4177151.841.1000110.8K101 D106 S107 R109K101-D104 HydrophobicContact CB-CB 3.7Å; K101-D104 HydrophobicContact CD-CB 4.44Å; K101-D104 PolarHBondContact O-N 3.07Å; K101-D104 VanDerWaalsContact O-N 3.09Å; D104-D106 PolarHBondContact OD1-N 3.37Å; D104-S107 PolarHBondContact OD1-N 2.97Å; D104-S107 PolarHBondContact OD1-OG 2.81Å; D104-S107 WeakPolarHBondContact OD2-CB 3.39Å; D104-S107 PolarHBondContact OD2-OG 2.99Å; D104-R109 VanDerWaalsContact CG-NH2 3.27Å; D104-R109 IonicContact OD2-CZ 3.86Å; D104-R109 IonicContact OD2-NE 3.6Å; D104-R109 IonicContact OD2-NH2 3.85Å; D104-R109 PolarHBondContact OD2-NH2 2.81Å
105R88.7Confident94Very high108 Ų10843.8 Ų43.841%0.40821%0.207SC..  trans-126.49.7-170.9-67.3-59.5177.8-85.2-10.3111.4P102 E103 Y190P102-R105 PolarHBondContact O-NH1 2.83Å; P102-R105 VanDerWaalsContact O-NH1 3.09Å; E103-R105 VanDerWaalsContact C-NH1 3.32Å; E103-R105 WeakPolarHBondContact O-CG 3.41Å; E103-R105 PolarHBondContact O-N 3.49Å; E103-R105 PolarHBondContact O-NH1 2.04Å; E103-R105 IonicContact OE2-CZ 2.88Å; E103-R105 IonicContact OE2-NH1 3.68Å; E103-R105 IonicContact OE2-NH2 3.78Å; E103-R105 PolarHBondContact OE2-NH2 3.43Å; R105-Y190 WeakPolarHBondContact CA-OH 3.38Å; R105-Y190 HydrophobicContact CB-CE1 4.11Å; R105-Y190 HydrophobicContact CB-CE2 4.22Å; R105-Y190 WeakPolarHBondContact CB-OH 3.38Å; R105-Y190 VanDerWaalsContact CD-CZ 3.46Å; R105-Y190 HydrophobicContact CG-CE2 4.19Å; R105-Y190 WeakPolarHBondContact O-CE1 3.37Å; R105-Y190 PolarHBondContact O-OH 2.98Å
106D92Very high93Very high121 Ų12146 Ų4665%0.64722%0.221SC*.SBendtrans-108.5-12.2178.4-57.4-36.6000111.2D104 P192D104-D106 PolarHBondContact OD1-N 3.37Å; D106-P192 VanDerWaalsContact O-CG 3.3Å; D106-P192 WeakPolarHBondContact O-CG 3.16Å
107S95.6Very high91.7Very high8 Ų849.4 Ų49.46%0.05625%0.25CC..SBendtrans-101.3133.4-179.4-54.40000112.3Y27 D104 R109 S127 Y190 P192Y27-S107 VanDerWaalsContact CE2-CB 3.46Å; Y27-S107 WeakPolarHBondContact CE2-OG 3.25Å; D104-S107 PolarHBondContact OD1-N 2.97Å; D104-S107 PolarHBondContact OD1-OG 2.81Å; D104-S107 WeakPolarHBondContact OD2-CB 3.39Å; D104-S107 PolarHBondContact OD2-OG 2.99Å; S107-R109 PolarHBondContact O-N 2.63Å; S107-S127 CarbonylContact C-O 3.56Å; S107-S127 WeakPolarHBondContact CA-O 3.19Å; S107-S127 WeakPolarHBondContact CB-O 3.48Å; S107-Y190 VanDerWaalsContact O-CD1 3.26Å; S107-Y190 WeakPolarHBondContact O-CD1 3.32Å; S107-P192 VanDerWaalsContact C-CG 3.49Å
108L97.4Very high90.3Very high0 Ų051.8 Ų51.80%027%0.27CS..EExtended strand (participates in β ladder)trans-59.8130.2166.717568.4000109.2L125 M126 S127 L172 L191 F195L108-L125 HydrophobicContact CD2-CD2 4.23Å; L108-L125 HydrophobicContact CD2-CG 4.42Å; L108-M126 VanDerWaalsContact O-CA 3.32Å; L108-M126 WeakPolarHBondContact O-CA 3.43Å; L108-S127 PolarHBondContact N-O 3.22Å; L108-S127 PolarHBondContact O-N 3.1Å; L108-L172 HydrophobicContact CD2-CD1 3.95Å; L108-L172 HydrophobicContact CD2-CD2 4.32Å; L108-L191 HydrophobicContact CD1-CD2 3.34Å; L108-F195 HydrophobicContact CB-CD2 4Å; L108-F195 HydrophobicContact CB-CE1 4.4Å; L108-F195 HydrophobicContact CB-CE2 3.84Å; L108-F195 HydrophobicContact CB-CG 4.36Å; L108-F195 HydrophobicContact CB-CZ 4.06Å; L108-F195 HydrophobicContact CD1-CB 4.27Å; L108-F195 HydrophobicContact CD1-CD1 4.21Å; L108-F195 HydrophobicContact CD1-CD2 4.44Å; L108-F195 HydrophobicContact CD1-CG 4.05Å; L108-F195 HydrophobicContact CD2-CD1 4Å; L108-F195 HydrophobicContact CD2-CE1 3.83Å; L108-F195 HydrophobicContact CD2-CZ 4.22Å; L108-F195 HydrophobicContact CG-CD1 4.48Å
109R97.2Very high89.4Confident8 Ų851.3 Ų51.33%0.0327%0.267CS..EExtended strand (participates in β ladder)trans-134.5123.3173.1-54.3171.5178.8-160.1-11.6108.4Y27 K101 P102 D104 S107 M126 L188 H189 Y190Y27-R109 PolarHBondContact OH-NH2 2.85Å; K101-R109 VanDerWaalsContact O-CZ 3.3Å; K101-R109 PolarHBondContact O-NH1 2.95Å; K101-R109 PolarHBondContact O-NH2 2.89Å; P102-R109 PolarHBondContact O-NH1 3.03Å; D104-R109 VanDerWaalsContact CG-NH2 3.27Å; D104-R109 IonicContact OD2-CZ 3.86Å; D104-R109 IonicContact OD2-NE 3.6Å; D104-R109 IonicContact OD2-NH2 3.85Å; D104-R109 PolarHBondContact OD2-NH2 2.81Å; S107-R109 PolarHBondContact O-N 2.63Å; R109-M126 VanDerWaalsContact CA-SD 3.54Å; R109-M126 HydrophobicContact CB-CE 4.03Å; R109-M126 HydrophobicContact CB-SD 3.56Å; R109-M126 VanDerWaalsContact CB-SD 3.56Å; R109-M126 HydrophobicContact CG-CE 4.48Å; R109-M126 HydrophobicContact CG-SD 3.58Å; R109-M126 VanDerWaalsContact CG-SD 3.58Å; R109-L188 HydrophobicContact CB-CD2 4.29Å; R109-H189 CarbonylContact O-C 3.6Å; R109-H189 WeakPolarHBondContact O-CA 3.3Å; R109-Y190 PolarHBondContact N-O 3.33Å; R109-Y190 PolarHBondContact O-N 3.41Å
110L97.5Very high88.9Confident0 Ų051.1 Ų51.10%027%0.269CS..EExtended strand (participates in β ladder)trans-142.9126.1177.8-167.7162.6000108.4Y112 V124 L125 V186 L188 L203L110-Y112 HydrophobicContact CD2-CD1 3.39Å; L110-Y112 HydrophobicContact CD2-CE1 4.33Å; L110-Y112 HydrophobicContact CD2-CG 4.03Å; L110-V124 WeakPolarHBondContact O-CA 3.27Å; L110-L125 HydrophobicContact CB-CB 4.29Å; L110-L125 PolarHBondContact N-O 3.5Å; L110-L125 PolarHBondContact O-N 3.18Å; L110-V186 HydrophobicContact CD1-CG1 4.41Å; L110-V186 HydrophobicContact CD2-CG1 4.01Å; L110-V186 HydrophobicContact CD2-CG2 4.17Å; L110-V186 HydrophobicContact CG-CG1 3.81Å; L110-L188 CarbonylContact C-O 3.54Å; L110-L188 WeakPolarHBondContact CA-O 3.09Å; L110-L203 HydrophobicContact CD1-CD2 3.64Å; L110-L203 HydrophobicContact CD1-CG 4.36Å
111M98Very high88.9Confident0 Ų046 Ų460%025%0.245CC..EExtended strand (participates in β ladder)trans-122.1132.3168.1-51175.6177.600108.9Y98 G123 V124 M126 P143 Y187 L188Y98-M111 HydrophobicContact CD1-CE 4.25Å; Y98-M111 HydrophobicContact CE1-CE 3.67Å; Y98-M111 HydrophobicContact CE2-CE 3.98Å; M111-G123 WeakPolarHBondContact CA-O 3.35Å; M111-V124 HydrophobicContact CG-CG1 4.37Å; M111-V124 HydrophobicContact CG-CG2 4.3Å; M111-M126 HydrophobicContact CE-CE 3.62Å; M111-M126 HydrophobicContact CG-CE 4.18Å; M111-P143 HydrophobicContact CE-CG 3.67Å; M111-P143 HydrophobicContact SD-CG 3.91Å; M111-Y187 HydrophobicContact CB-CD2 4.18Å; M111-Y187 HydrophobicContact CB-CE1 4.25Å; M111-Y187 HydrophobicContact CB-CE2 3.41Å; M111-Y187 VanDerWaalsContact CB-CE2 3.41Å; M111-Y187 VanDerWaalsContact CB-CZ 3.46Å; M111-Y187 WeakPolarHBondContact CB-OH 3.44Å; M111-Y187 HydrophobicContact CG-CE2 4.37Å; M111-Y187 PolarHBondContact O-N 3.05Å; M111-Y187 HydrophobicContact SD-CE2 4.1Å; M111-L188 HydrophobicContact CB-CB 4.03Å; M111-L188 HydrophobicContact CE-CD1 4.41Å; M111-L188 HydrophobicContact CE-CD2 4.42Å; M111-L188 HydrophobicContact CG-CB 4.18Å; M111-L188 HydrophobicContact CG-CD2 4.09Å; M111-L188 PolarHBondContact N-O 2.88Å; M111-L188 PolarHBondContact O-N 3.4Å; M111-L188 HydrophobicContact SD-CB 4.19Å; M111-L188 HydrophobicContact SD-CD1 4.03Å; M111-L188 HydrophobicContact SD-CD2 4.26Å; M111-L188 HydrophobicContact SD-CG 4.39Å
112Y97.3Very high89.2Confident2 Ų241.1 Ų41.11%0.00822%0.224CC..EExtended strand (participates in β ladder)trans-141.5165.3-173.869.7-88.1000111.9L110 Y122 G123 W134 L136 L179 P184 W185 Y187L110-Y112 HydrophobicContact CD2-CD1 3.39Å; L110-Y112 HydrophobicContact CD2-CE1 4.33Å; L110-Y112 HydrophobicContact CD2-CG 4.03Å; Y112-Y122 VanDerWaalsContact O-CA 3.27Å; Y112-Y122 WeakPolarHBondContact O-CA 3.25Å; Y112-G123 VanDerWaalsContact CD1-O 3.29Å; Y112-G123 WeakPolarHBondContact CD1-O 3.31Å; Y112-G123 VanDerWaalsContact CE1-CA 3.41Å; Y112-G123 PolarHBondContact N-O 3.46Å; Y112-G123 PolarHBondContact O-N 3.41Å; Y112-W134 AromaticContact CE1-NE1 3.98Å; Y112-W134 AromaticContact CZ-NE1 3.87Å; Y112-W134 WeakPolarHBondContact OH-CZ2 3Å; Y112-W134 PolarHBondContact OH-NE1 3.38Å; Y112-L136 WeakPolarHBondContact OH-CD2 3.18Å; Y112-L179 HydrophobicContact CD1-CD2 3.87Å; Y112-L179 HydrophobicContact CD2-CD1 3.95Å; Y112-L179 HydrophobicContact CD2-CD2 4.29Å; Y112-L179 HydrophobicContact CE1-CD1 4.37Å; Y112-L179 HydrophobicContact CE1-CD2 3.57Å; Y112-L179 HydrophobicContact CE2-CD1 3.38Å; Y112-L179 HydrophobicContact CE2-CD2 4.06Å; Y112-L179 HydrophobicContact CE2-CG 4.37Å; Y112-L179 HydrophobicContact CG-CD2 4.19Å; Y112-P184 HydrophobicContact CD2-CB 3.64Å; Y112-P184 HydrophobicContact CD2-CG 4.41Å; Y112-P184 HydrophobicContact CE2-CB 4.47Å; Y112-P184 HydrophobicContact CG-CB 4.21Å; Y112-W185 CarbonylContact C-O 3.54Å; Y112-W185 WeakPolarHBondContact CA-O 3.09Å; Y112-Y187 WeakPolarHBondContact O-CE1 3.48Å
113T96.7Very high89.6Confident9 Ų937.2 Ų37.26%0.05520%0.199CC..EExtended strand (participates in β ladder)trans-138.3145.8173.9-171.80000111.5K115 S121 Y122 P184 W185 Y187T113-K115 HydrophobicContact CG2-CB 4.18Å; T113-K115 WeakPolarHBondContact OG1-CB 3.2Å; T113-K115 PolarHBondContact OG1-N 3.01Å; T113-S121 VanDerWaalsContact CA-O 3.3Å; T113-S121 WeakPolarHBondContact CA-O 2.93Å; T113-S121 PolarHBondContact OG1-O 3.3Å; T113-Y122 VanDerWaalsContact CB-CD1 3.45Å; T113-Y122 HydrophobicContact CG2-CE1 4.42Å; T113-Y122 WeakPolarHBondContact OG1-CD1 3.46Å; T113-Y122 WeakPolarHBondContact OG1-CE1 3.32Å; T113-P184 CarbonylContact O-C 3.57Å; T113-P184 WeakPolarHBondContact O-CA 3.16Å; T113-W185 HydrophobicContact CG2-CB 4.08Å; T113-W185 HydrophobicContact CG2-CE3 3.7Å; T113-W185 PolarHBondContact N-O 2.9Å; T113-W185 PolarHBondContact O-N 2.85Å; T113-Y187 HydrophobicContact CG2-CD1 4.21Å; T113-Y187 HydrophobicContact CG2-CE1 4.43Å
114T91.8Very high89.9Confident12 Ų1230.7 Ų30.77%0.07417%0.168CC..  trans-108.426.6165.3560000110.5V116 S121 E182 P184T114-V116 PolarHBondContact O-N 3.36Å; T114-S121 PolarHBondContact N-O 2.79Å; T114-E182 HydrophobicContact CG2-CB 3.77Å; T114-E182 WeakPolarHBondContact CG2-OE2 3.11Å; T114-P184 HydrophobicContact CG2-CB 3.87Å
115K80.4Confident90.3Very high97 Ų9729.6 Ų29.642%0.42216%0.162SC..  trans-55.9125.3179.3177.7174.9-164.81540110.5T113 R119 N120 Y122 D140T113-K115 HydrophobicContact CG2-CB 4.18Å; T113-K115 WeakPolarHBondContact OG1-CB 3.2Å; T113-K115 PolarHBondContact OG1-N 3.01Å; K115-R119 VanDerWaalsContact CA-O 3.27Å; K115-R119 WeakPolarHBondContact CA-O 3.33Å; K115-N120 WeakPolarHBondContact CD-OD1 3.48Å; K115-N120 WeakPolarHBondContact CE-OD1 3.32Å; K115-N120 WeakPolarHBondContact CG-OD1 3.3Å; K115-N120 PolarHBondContact NZ-OD1 2.75Å; K115-Y122 WeakPolarHBondContact CD-OH 3.08Å; K115-Y122 PolarHBondContact NZ-OH 2.98Å; K115-D140 IonicContact NZ-OD1 3.14Å; K115-D140 PolarHBondContact NZ-OD1 3.36Å; K115-D140 IonicContact NZ-OD2 3.8Å; K115-D140 PolarHBondContact NZ-OD2 3.04Å
116V77.4Confident90.7Very high47 Ų4724.4 Ų24.429%0.28514%0.143SC..BIsolated β-bridgetrans-123.5164.7168.2-67.30000107.4T114 A118 R119 L330T114-V116 PolarHBondContact O-N 3.36Å; V116-A118 PolarHBondContact O-N 2.85Å; V116-R119 HydrophobicContact CG2-CB 3.83Å; V116-R119 PolarHBondContact N-O 3.42Å; V116-R119 VanDerWaalsContact N-O 3.1Å; V116-R119 PolarHBondContact O-N 2.89Å; V116-L330 HydrophobicContact CG2-CD1 4.18Å
117S68.9Low91Very high104 Ų10418.7 Ų18.773%0.72711%0.112SC*.THydrogen-bonded Turntrans-49.5-25-168.670.40000116R326S117-R326 PolarHBondContact OG-NH2 2.6Å
118A67.2Low90.9Very high53 Ų5319.6 Ų19.644%0.43812%0.116SC..THydrogen-bonded Turntrans-104.5-4.6-177.100000114.6V116V116-A118 PolarHBondContact O-N 2.85Å
119R75.3Confident90.7Very high5 Ų523.9 Ų23.92%0.01914%0.144CC..BIsolated β-bridgetrans-152.7134.4-161.4-173.3174.591.71794.8112.8K115 V116 N320 S321 E327 D331K115-R119 VanDerWaalsContact CA-O 3.27Å; K115-R119 WeakPolarHBondContact CA-O 3.33Å; V116-R119 HydrophobicContact CG2-CB 3.83Å; V116-R119 PolarHBondContact N-O 3.42Å; V116-R119 VanDerWaalsContact N-O 3.1Å; V116-R119 PolarHBondContact O-N 2.89Å; R119-N320 WeakPolarHBondContact CD-O 3.5Å; R119-N320 WeakPolarHBondContact CG-O 3.35Å; R119-N320 PolarHBondContact NE-O 3.48Å; R119-N320 PolarHBondContact NH1-O 3.1Å; R119-S321 VanDerWaalsContact NH1-CB 3.27Å; R119-S321 PolarHBondContact NH1-OG 3.41Å; R119-S321 VanDerWaalsContact NH1-OG 3.17Å; R119-E327 VanDerWaalsContact CD-OE1 3.25Å; R119-E327 WeakPolarHBondContact CD-OE1 3.09Å; R119-E327 IonicContact CZ-OE1 2.62Å; R119-E327 IonicContact CZ-OE2 3.05Å; R119-E327 IonicContact NE-OE1 2.68Å; R119-E327 IonicContact NH1-OE1 3.04Å; R119-E327 PolarHBondContact NH1-OE1 3.17Å; R119-E327 IonicContact NH1-OE2 3.77Å; R119-E327 PolarHBondContact NH1-OE2 2.99Å; R119-D331 PolarHBondContact NH2-O 3.3Å
120N86.1Confident90.5Very high34 Ų3428.7 Ų28.718%0.18217%0.167CC..  trans-113116.8177.5-69.6-21.9000108.3K115 Y122 D138K115-N120 WeakPolarHBondContact CD-OD1 3.48Å; K115-N120 WeakPolarHBondContact CE-OD1 3.32Å; K115-N120 WeakPolarHBondContact CG-OD1 3.3Å; K115-N120 PolarHBondContact NZ-OD1 2.75Å; N120-Y122 HydrophobicContact CB-CE2 3.78Å; N120-D138 WeakPolarHBondContact CB-O 3.43Å; N120-D138 WeakPolarHBondContact O-CA 3.36Å
121S95.3Very high90.5Very high2 Ų229.3 Ų29.31%0.01417%0.17CC..  trans-141.3135.9168.5-179.20000108.6T113 T114 N320T113-S121 VanDerWaalsContact CA-O 3.3Å; T113-S121 WeakPolarHBondContact CA-O 2.93Å; T113-S121 PolarHBondContact OG1-O 3.3Å; T114-S121 PolarHBondContact N-O 2.79Å; S121-N320 WeakPolarHBondContact OG-CB 3.26Å
122Y97.6Very high90.5Very high11 Ų1129.3 Ų29.34%0.04317%0.17CC..EExtended strand (participates in β ladder)trans-135.2155.7-172.2-58.3-82.6000109.3Y112 T113 K115 N120 H137 A139 D140 Y187Y112-Y122 VanDerWaalsContact O-CA 3.27Å; Y112-Y122 WeakPolarHBondContact O-CA 3.25Å; T113-Y122 VanDerWaalsContact CB-CD1 3.45Å; T113-Y122 HydrophobicContact CG2-CE1 4.42Å; T113-Y122 WeakPolarHBondContact OG1-CD1 3.46Å; T113-Y122 WeakPolarHBondContact OG1-CE1 3.32Å; K115-Y122 WeakPolarHBondContact CD-OH 3.08Å; K115-Y122 PolarHBondContact NZ-OH 2.98Å; N120-Y122 HydrophobicContact CB-CE2 3.78Å; Y122-H137 WeakPolarHBondContact CB-CE1 3.06Å; Y122-H137 WeakPolarHBondContact CB-NE2 3.38Å; Y122-H137 AromaticContact CD2-CE1 3.69Å; Y122-H137 AromaticContact CD2-ND1 3.81Å; Y122-H137 AromaticContact CG-CE1 3.63Å; Y122-H137 PolarHBondContact N-O 3.2Å; Y122-H137 PolarHBondContact O-N 3.23Å; Y122-A139 WeakPolarHBondContact CD2-O 3.39Å; Y122-A139 WeakPolarHBondContact CE2-O 3.38Å; Y122-D140 HydrophobicContact CE2-CB 4.47Å; Y122-D140 PolarHBondContact OH-OD1 2.74Å; Y122-Y187 HydrophobicContact CD1-CE1 4.25Å
123G98.3Very high90.5Very high0 Ų029.2 Ų29.20%017%0.17CC..EExtended strand (participates in β ladder)trans-141.8151.6168.100000112.7M111 Y112 L135M111-G123 WeakPolarHBondContact CA-O 3.35Å; Y112-G123 VanDerWaalsContact CD1-O 3.29Å; Y112-G123 WeakPolarHBondContact CD1-O 3.31Å; Y112-G123 VanDerWaalsContact CE1-CA 3.41Å; Y112-G123 PolarHBondContact N-O 3.46Å; Y112-G123 PolarHBondContact O-N 3.41Å; G123-L135 CarbonylContact C-O 3.38Å; G123-L135 WeakPolarHBondContact CA-O 2.87Å
124V98.7Very high90.6Very high0 Ų028.9 Ų28.90%017%0.168CC..EExtended strand (participates in β ladder)trans-124.9117.9176-177.30000107L95 L110 M111 M126 F133 W134 L135 P143L95-V124 HydrophobicContact CD2-CG1 4.15Å; L110-V124 WeakPolarHBondContact O-CA 3.27Å; M111-V124 HydrophobicContact CG-CG1 4.37Å; M111-V124 HydrophobicContact CG-CG2 4.3Å; V124-M126 HydrophobicContact CG1-CE 3.51Å; V124-M126 HydrophobicContact CG1-CG 3.77Å; V124-M126 HydrophobicContact CG1-SD 4.5Å; V124-F133 HydrophobicContact CB-CE2 4.46Å; V124-F133 HydrophobicContact CG1-CE2 3.99Å; V124-F133 HydrophobicContact CG1-CZ 4.38Å; V124-W134 WeakPolarHBondContact O-CA 3.45Å; V124-L135 HydrophobicContact CB-CB 4.19Å; V124-L135 HydrophobicContact CB-CD2 4.4Å; V124-L135 HydrophobicContact CG2-CD2 4.35Å; V124-L135 PolarHBondContact N-O 2.97Å; V124-L135 PolarHBondContact O-N 3.21Å; V124-P143 HydrophobicContact CG2-CG 3.82Å
125L98.4Very high91Very high0 Ų028.3 Ų28.30%016%0.164CC..EExtended strand (participates in β ladder)trans-116.7119.3176.7-167.568.9000107.8L108 L110 W134 L172 I175L108-L125 HydrophobicContact CD2-CD2 4.23Å; L108-L125 HydrophobicContact CD2-CG 4.42Å; L110-L125 HydrophobicContact CB-CB 4.29Å; L110-L125 PolarHBondContact N-O 3.5Å; L110-L125 PolarHBondContact O-N 3.18Å; L125-W134 HydrophobicContact CD1-CB 3.67Å; L125-W134 HydrophobicContact CD1-CG 3.88Å; L125-L172 HydrophobicContact CD1-CD2 3.56Å; L125-L172 HydrophobicContact CD2-CD2 3.8Å; L125-L172 HydrophobicContact CG-CD2 3.71Å; L125-I175 HydrophobicContact CD1-CG2 4.29Å; L125-I175 HydrophobicContact CD2-CG2 4.3Å
126M98.1Very high91.8Very high0 Ų024.2 Ų24.20%015%0.147CC..EExtended strand (participates in β ladder)trans-134138-176.9-60.6-77172.400109.3Y27 Y98 L108 R109 M111 V124 A132 F133Y27-M126 HydrophobicContact CD1-CB 3.39Å; Y27-M126 HydrophobicContact CD1-CG 4.3Å; Y27-M126 HydrophobicContact CE1-CB 3.58Å; Y27-M126 HydrophobicContact CE1-CG 4.14Å; Y27-M126 HydrophobicContact CE1-SD 4.36Å; Y27-M126 HydrophobicContact CG-CB 4.06Å; Y98-M126 HydrophobicContact CD2-CE 3.87Å; Y98-M126 HydrophobicContact CD2-SD 4.24Å; Y98-M126 HydrophobicContact CE2-CE 4.24Å; Y98-M126 HydrophobicContact CG-CE 4.26Å; L108-M126 VanDerWaalsContact O-CA 3.32Å; L108-M126 WeakPolarHBondContact O-CA 3.43Å; R109-M126 VanDerWaalsContact CA-SD 3.54Å; R109-M126 HydrophobicContact CB-CE 4.03Å; R109-M126 HydrophobicContact CB-SD 3.56Å; R109-M126 VanDerWaalsContact CB-SD 3.56Å; R109-M126 HydrophobicContact CG-CE 4.48Å; R109-M126 HydrophobicContact CG-SD 3.58Å; R109-M126 VanDerWaalsContact CG-SD 3.58Å; M111-M126 HydrophobicContact CE-CE 3.62Å; M111-M126 HydrophobicContact CG-CE 4.18Å; V124-M126 HydrophobicContact CG1-CE 3.51Å; V124-M126 HydrophobicContact CG1-CG 3.77Å; V124-M126 HydrophobicContact CG1-SD 4.5Å; M126-A132 CarbonylContact O-C 3.49Å; M126-A132 VanDerWaalsContact O-CA 3.23Å; M126-A132 WeakPolarHBondContact O-CA 3.23Å; M126-F133 HydrophobicContact CB-CD1 4.28Å; M126-F133 HydrophobicContact CB-CE1 3.78Å; M126-F133 HydrophobicContact CB-CE2 4.16Å; M126-F133 HydrophobicContact CB-CZ 3.68Å; M126-F133 HydrophobicContact CG-CE1 4.12Å; M126-F133 HydrophobicContact CG-CE2 3.99Å; M126-F133 HydrophobicContact CG-CZ 3.53Å; M126-F133 PolarHBondContact N-O 3.23Å; M126-F133 VanDerWaalsContact N-O 3.12Å; M126-F133 PolarHBondContact O-N 2.52Å
127S97.5Very high92.8Very high0 Ų022 Ų220%013%0.133CC..EExtended strand (participates in β ladder)trans-150.9146179.7-164.80000112.2Y27 S107 L108 N131 L172Y27-S127 VanDerWaalsContact CD2-C 3.48Å; S107-S127 CarbonylContact C-O 3.56Å; S107-S127 WeakPolarHBondContact CA-O 3.19Å; S107-S127 WeakPolarHBondContact CB-O 3.48Å; L108-S127 PolarHBondContact N-O 3.22Å; L108-S127 PolarHBondContact O-N 3.1Å; S127-N131 CarbonylContact C-O 3.49Å; S127-N131 VanDerWaalsContact CA-O 3.24Å; S127-N131 WeakPolarHBondContact CA-O 2.99Å; S127-N131 PolarHBondContact OG-O 2.87Å; S127-N131 VanDerWaalsContact OG-O 3.07Å; S127-L172 VanDerWaalsContact CB-CD1 3.49Å; S127-L172 WeakPolarHBondContact OG-CD1 3.46Å
128N94.5Very high94.2Very high27 Ų2717 Ų1714%0.14410%0.099CC..  trans-111.6-174.9155.763.88.5000108.3D26 Y27 E130 N131 P169D26-N128 PolarHBondContact OD1-ND2 3.38Å; D26-N128 PolarHBondContact OD1-OD1 2.99Å; Y27-N128 HydrophobicContact CD2-CB 3.81Å; Y27-N128 HydrophobicContact CE2-CB 4.22Å; N128-E130 PolarHBondContact O-N 3.39Å; N128-E130 PolarHBondContact OD1-N 3.34Å; N128-N131 PolarHBondContact N-O 3.3Å; N128-N131 PolarHBondContact OD1-N 3.23Å; N128-N131 PolarHBondContact OD1-O 3.06Å; N128-N131 VanDerWaalsContact OD1-O 3.04Å; N128-P169 WeakPolarHBondContact O-CG 3.28Å
129P92.3Very high95.5Very high90 Ų9014.5 Ų14.558%0.5848%0.078SC*.SBendtrans-59.8-24.5-180-2837.6000115
130E93.4Very high96.4Very high110 Ų11017 Ų1751%0.5149%0.091SC..SBendtrans-99.8-33.1-173.7-6377-166.900114.2N128 K223N128-E130 PolarHBondContact O-N 3.39Å; N128-E130 PolarHBondContact OD1-N 3.34Å; E130-K223 PolarHBondContact O-NZ 3.27Å
131N96.6Very high96.8Very high12 Ų1218.7 Ų18.76%0.06411%0.11CC..  trans-144.5146.5-168.4-59.2-72.9000112.1D26 Y27 L28 S127 N128 K223D26-N131 WeakPolarHBondContact OD1-CB 3.23Å; D26-N131 PolarHBondContact OD1-ND2 2.77Å; D26-N131 PolarHBondContact OD2-ND2 2.87Å; Y27-N131 CarbonylContact O-C 3.59Å; Y27-N131 WeakPolarHBondContact O-CB 3.48Å; L28-N131 HydrophobicContact CD2-CB 3.85Å; L28-N131 HydrophobicContact CG-CB 3.93Å; S127-N131 CarbonylContact C-O 3.49Å; S127-N131 VanDerWaalsContact CA-O 3.24Å; S127-N131 WeakPolarHBondContact CA-O 2.99Å; S127-N131 PolarHBondContact OG-O 2.87Å; S127-N131 VanDerWaalsContact OG-O 3.07Å; N128-N131 PolarHBondContact N-O 3.3Å; N128-N131 PolarHBondContact OD1-N 3.23Å; N128-N131 PolarHBondContact OD1-O 3.06Å; N128-N131 VanDerWaalsContact OD1-O 3.04Å; N131-K223 VanDerWaalsContact OD1-CD 3.26Å; N131-K223 WeakPolarHBondContact OD1-CD 3.26Å; N131-K223 WeakPolarHBondContact OD1-CE 3.4Å; N131-K223 PolarHBondContact OD1-NZ 3.03Å
132A98.1Very high96.9Very high0 Ų018.7 Ų18.70%011%0.11CC..EExtended strand (participates in β ladder)trans-132.4151.6170.400000110.8Y27 M126 S166 F167 L172Y27-A132 CarbonylContact O-C 3.59Å; Y27-A132 WeakPolarHBondContact O-CA 3.16Å; Y27-A132 PolarHBondContact O-N 2.79Å; M126-A132 CarbonylContact O-C 3.49Å; M126-A132 VanDerWaalsContact O-CA 3.23Å; M126-A132 WeakPolarHBondContact O-CA 3.23Å; A132-S166 CarbonylContact O-C 3.6Å; A132-S166 WeakPolarHBondContact O-CA 3.33Å; A132-F167 HydrophobicContact CB-CB 4.41Å; A132-F167 PolarHBondContact N-O 3.12Å; A132-F167 PolarHBondContact O-N 3.12Å; A132-L172 HydrophobicContact CB-CD1 4.11Å; A132-L172 HydrophobicContact CB-CD2 3.88Å; A132-L172 HydrophobicContact CB-CG 4.13Å
133F98.6Very high96.9Very high0 Ų018.4 Ų18.40%011%0.109CC..EExtended strand (participates in β ladder)trans-128.2151.7159.873.4-107.6000110.9Y27 T94 L95 V124 M126 L135 V165Y27-F133 HydrophobicContact CD1-CD1 4.21Å; Y27-F133 AromaticContact CD1-CE1 3.71Å; Y27-F133 HydrophobicContact CD1-CE1 3.71Å; Y27-F133 PolarHBondContact O-N 3.29Å; T94-F133 HydrophobicContact CG2-CD1 3.87Å; T94-F133 HydrophobicContact CG2-CD2 4.2Å; T94-F133 HydrophobicContact CG2-CE1 3.76Å; T94-F133 HydrophobicContact CG2-CE2 4.17Å; T94-F133 HydrophobicContact CG2-CG 4.09Å; T94-F133 HydrophobicContact CG2-CZ 3.95Å; T94-F133 VanDerWaalsContact O-CE1 3.29Å; T94-F133 WeakPolarHBondContact O-CE1 3.47Å; L95-F133 HydrophobicContact CD2-CE2 4.47Å; L95-F133 HydrophobicContact CD2-CZ 4.03Å; V124-F133 HydrophobicContact CB-CE2 4.46Å; V124-F133 HydrophobicContact CG1-CE2 3.99Å; V124-F133 HydrophobicContact CG1-CZ 4.38Å; M126-F133 HydrophobicContact CB-CD1 4.28Å; M126-F133 HydrophobicContact CB-CE1 3.78Å; M126-F133 HydrophobicContact CB-CE2 4.16Å; M126-F133 HydrophobicContact CB-CZ 3.68Å; M126-F133 HydrophobicContact CG-CE1 4.12Å; M126-F133 HydrophobicContact CG-CE2 3.99Å; M126-F133 HydrophobicContact CG-CZ 3.53Å; M126-F133 PolarHBondContact N-O 3.23Å; M126-F133 VanDerWaalsContact N-O 3.12Å; M126-F133 PolarHBondContact O-N 2.52Å; F133-L135 HydrophobicContact CD2-CB 4.12Å; F133-L135 HydrophobicContact CE2-CB 4.09Å; F133-V165 CarbonylContact C-O 3.08Å; F133-V165 WeakPolarHBondContact CA-O 3.29Å
134W98.8Very high96.9Very high3 Ų320.2 Ų20.21%0.01112%0.122CC..EExtended strand (participates in β ladder)trans-121.2118.1168.5-175.324.6000108.9Y112 V124 L125 L136 C164 V165 F167 I175 L220 Y235 V335Y112-W134 AromaticContact CE1-NE1 3.98Å; Y112-W134 AromaticContact CZ-NE1 3.87Å; Y112-W134 WeakPolarHBondContact OH-CZ2 3Å; Y112-W134 PolarHBondContact OH-NE1 3.38Å; V124-W134 WeakPolarHBondContact O-CA 3.45Å; L125-W134 HydrophobicContact CD1-CB 3.67Å; L125-W134 HydrophobicContact CD1-CG 3.88Å; W134-L136 HydrophobicContact CD2-CG 4.45Å; W134-L136 HydrophobicContact CH2-CD1 4.29Å; W134-L136 HydrophobicContact CZ2-CD1 4.12Å; W134-L136 HydrophobicContact CZ2-CD2 3.64Å; W134-L136 HydrophobicContact CZ2-CG 4.19Å; W134-C164 CarbonylContact O-C 3.49Å; W134-C164 WeakPolarHBondContact O-CA 3.5Å; W134-V165 PolarHBondContact N-O 3.12Å; W134-V165 PolarHBondContact O-N 2.85Å; W134-F167 HydrophobicContact CB-CD2 4.25Å; W134-F167 HydrophobicContact CB-CE2 4.1Å; W134-F167 HydrophobicContact CE3-CE2 4.11Å; W134-I175 HydrophobicContact CD2-CG2 4.14Å; W134-I175 HydrophobicContact CE3-CD1 4.2Å; W134-I175 HydrophobicContact CE3-CG1 4.37Å; W134-I175 HydrophobicContact CE3-CG2 4.2Å; W134-I175 HydrophobicContact CH2-CG2 4.49Å; W134-I175 HydrophobicContact CZ2-CG2 4.41Å; W134-I175 HydrophobicContact CZ3-CG2 4.38Å; W134-L220 HydrophobicContact CZ3-CD1 4.43Å; W134-Y235 AromaticContact CH2-CD1 3.56Å; W134-Y235 HydrophobicContact CH2-CD1 3.56Å; W134-Y235 AromaticContact CH2-CD2 3.98Å; W134-Y235 HydrophobicContact CH2-CD2 3.98Å; W134-Y235 AromaticContact CH2-CE1 3.39Å; W134-Y235 HydrophobicContact CH2-CE1 3.39Å; W134-Y235 AromaticContact CH2-CE2 3.82Å; W134-Y235 HydrophobicContact CH2-CE2 3.82Å; W134-Y235 AromaticContact CH2-CG 3.86Å; W134-Y235 HydrophobicContact CH2-CG 3.86Å; W134-Y235 AromaticContact CH2-CZ 3.52Å; W134-Y235 HydrophobicContact CZ2-CE1 4.01Å; W134-Y235 HydrophobicContact CZ2-CE2 4.46Å; W134-Y235 AromaticContact CZ2-CZ 3.95Å; W134-Y235 AromaticContact CZ3-CD1 3.94Å; W134-Y235 HydrophobicContact CZ3-CD1 3.94Å; W134-Y235 HydrophobicContact CZ3-CE1 4.17Å; W134-Y235 HydrophobicContact CZ3-CG 4.21Å; W134-V335 HydrophobicContact CH2-CG2 3.48Å; W134-V335 VanDerWaalsContact CH2-CG2 3.48Å; W134-V335 HydrophobicContact CZ2-CG2 4.35Å; W134-V335 HydrophobicContact CZ3-CG1 4.22Å; W134-V335 HydrophobicContact CZ3-CG2 3.79Å
135L98.9Very high96.7Very high0 Ų025.9 Ų25.90%015%0.146CC..EExtended strand (participates in β ladder)trans-109.9125.3177.8171.372.4000108.8F41 L91 G123 V124 F133 F142 L162 F163 C164F41-L135 HydrophobicContact CZ-CD1 4.46Å; L91-L135 HydrophobicContact CD1-CD1 4.23Å; L91-L135 HydrophobicContact CD1-CD2 3.77Å; G123-L135 CarbonylContact C-O 3.38Å; G123-L135 WeakPolarHBondContact CA-O 2.87Å; V124-L135 HydrophobicContact CB-CB 4.19Å; V124-L135 HydrophobicContact CB-CD2 4.4Å; V124-L135 HydrophobicContact CG2-CD2 4.35Å; V124-L135 PolarHBondContact N-O 2.97Å; V124-L135 PolarHBondContact O-N 3.21Å; F133-L135 HydrophobicContact CD2-CB 4.12Å; F133-L135 HydrophobicContact CE2-CB 4.09Å; L135-F142 HydrophobicContact CD2-CE1 4.21Å; L135-L162 HydrophobicContact CD1-CB 4.21Å; L135-F163 CarbonylContact C-O 3.6Å; L135-F163 WeakPolarHBondContact CA-O 3.36Å; L135-C164 HydrophobicContact CD1-CB 3.87Å
136L98.8Very high96.5Very high10 Ų1036.6 Ų36.65%0.05219%0.187CC..EExtended strand (participates in β ladder)trans-109.1138.2174.3-65.9166.7000109.2Y112 W134 L162 F163 Y318 V335Y112-L136 WeakPolarHBondContact OH-CD2 3.18Å; W134-L136 HydrophobicContact CD2-CG 4.45Å; W134-L136 HydrophobicContact CH2-CD1 4.29Å; W134-L136 HydrophobicContact CZ2-CD1 4.12Å; W134-L136 HydrophobicContact CZ2-CD2 3.64Å; W134-L136 HydrophobicContact CZ2-CG 4.19Å; L136-L162 CarbonylContact O-C 3.27Å; L136-L162 VanDerWaalsContact O-CA 3.32Å; L136-L162 WeakPolarHBondContact O-CA 3.13Å; L136-F163 HydrophobicContact CD1-CD1 4.39Å; L136-F163 PolarHBondContact N-O 2.86Å; L136-F163 PolarHBondContact O-N 2.91Å; L136-Y318 HydrophobicContact CB-CD1 4.09Å; L136-Y318 HydrophobicContact CB-CE1 3.88Å; L136-Y318 HydrophobicContact CB-CE2 4.39Å; L136-Y318 HydrophobicContact CB-CG 4.45Å; L136-Y318 HydrophobicContact CD1-CD1 3.98Å; L136-Y318 HydrophobicContact CD1-CE1 4.42Å; L136-V335 HydrophobicContact CD1-CB 3.89Å; L136-V335 HydrophobicContact CD1-CG1 4.38Å; L136-V335 HydrophobicContact CD1-CG2 3.57Å
137H98.3Very high96.5Very high0 Ų041.5 Ų41.50%022%0.216CC..EExtended strand (participates in β ladder)trans-159.1165.5176.166.392.1000113.5Y122 A139 F142 L161 L162 Y318Y122-H137 WeakPolarHBondContact CB-CE1 3.06Å; Y122-H137 WeakPolarHBondContact CB-NE2 3.38Å; Y122-H137 AromaticContact CD2-CE1 3.69Å; Y122-H137 AromaticContact CD2-ND1 3.81Å; Y122-H137 AromaticContact CG-CE1 3.63Å; Y122-H137 PolarHBondContact N-O 3.2Å; Y122-H137 PolarHBondContact O-N 3.23Å; H137-A139 PolarHBondContact CE1-O 3.38Å; H137-A139 VanDerWaalsContact CE1-O 3.3Å; H137-A139 PolarHBondContact ND1-N 2.91Å; H137-A139 PolarHBondContact ND1-O 2.92Å; H137-F142 AromaticContact CE1-CD1 3.69Å; H137-F142 PolarHBondContact CE1-O 3.02Å; H137-F142 AromaticContact ND1-CD1 3.97Å; H137-F142 AromaticContact NE2-CD1 3.76Å; H137-F142 PolarHBondContact NE2-O 3.03Å; H137-L161 WeakPolarHBondContact CA-O 3.45Å; H137-L162 HydrophobicContact CB-CB 4.18Å; H137-L162 HydrophobicContact CB-CD2 3.87Å; H137-L162 HydrophobicContact CB-CG 3.69Å; H137-Y318 WeakPolarHBondContact CA-OH 3.42Å; H137-Y318 PolarHBondContact O-OH 2.8Å
138D96.5Very high96.5Very high1 Ų143 Ų431%0.00522%0.222CC..  trans-105.5-10.7177.247.215000113.7N120 D140 Q160 L161 S303N120-D138 WeakPolarHBondContact CB-O 3.43Å; N120-D138 WeakPolarHBondContact O-CA 3.36Å; D138-D140 PolarHBondContact O-N 3.31Å; D138-Q160 VanDerWaalsContact C-OE1 3.29Å; D138-Q160 VanDerWaalsContact CG-OE1 3.29Å; D138-Q160 PolarHBondContact O-OE1 2.88Å; D138-Q160 VanDerWaalsContact OD1-CA 3.25Å; D138-Q160 WeakPolarHBondContact OD1-CA 3.49Å; D138-Q160 WeakPolarHBondContact OD1-CB 3.44Å; D138-Q160 PolarHBondContact OD1-OE1 2.96Å; D138-L161 VanDerWaalsContact CG-N 3.33Å; D138-L161 PolarHBondContact OD1-N 3.07Å; D138-L161 PolarHBondContact OD2-N 3.19Å; D138-S303 WeakPolarHBondContact OD2-CA 3.25Å; D138-S303 PolarHBondContact OD2-N 2.89Å
139A96.4Very high96.7Very high0 Ų043.8 Ų43.80%023%0.233CC..  trans-64.7114.4-178.500000113.5Y122 H137 F142 W150 A155 Q160Y122-A139 WeakPolarHBondContact CD2-O 3.39Å; Y122-A139 WeakPolarHBondContact CE2-O 3.38Å; H137-A139 PolarHBondContact CE1-O 3.38Å; H137-A139 VanDerWaalsContact CE1-O 3.3Å; H137-A139 PolarHBondContact ND1-N 2.91Å; H137-A139 PolarHBondContact ND1-O 2.92Å; A139-F142 HydrophobicContact CB-CB 4.02Å; A139-F142 PolarHBondContact O-N 2.84Å; A139-W150 HydrophobicContact CB-CH2 3.64Å; A139-W150 HydrophobicContact CB-CZ2 3.93Å; A139-W150 HydrophobicContact CB-CZ3 4.46Å; A139-A155 HydrophobicContact CB-CB 4.08Å; A139-Q160 HydrophobicContact CB-CB 4.4Å; A139-Q160 HydrophobicContact CB-CG 4.22Å
140D93.8Very high96.9Very high56 Ų5640.2 Ų40.230%0.29921%0.208SC..THydrogen-bonded Turntrans-65.9146.4178.5-156.16.7000112.3K115 Y122 D138 F142 P151K115-D140 IonicContact NZ-OD1 3.14Å; K115-D140 PolarHBondContact NZ-OD1 3.36Å; K115-D140 IonicContact NZ-OD2 3.8Å; K115-D140 PolarHBondContact NZ-OD2 3.04Å; Y122-D140 HydrophobicContact CE2-CB 4.47Å; Y122-D140 PolarHBondContact OH-OD1 2.74Å; D138-D140 PolarHBondContact O-N 3.31Å; D140-F142 PolarHBondContact O-N 2.98Å; D140-F142 VanDerWaalsContact O-N 3.1Å; D140-P151 WeakPolarHBondContact O-CB 3.39Å; D140-P151 WeakPolarHBondContact O-CG 3.32Å
141A94.1Very high97.1Very high71 Ų7135.7 Ų35.759%0.58719%0.188SC*.THydrogen-bonded Turntrans57.614.4-176.700000116P151A141-P151 HydrophobicContact CB-CB 4.12Å; A141-P151 HydrophobicContact CB-CG 4.25Å; A141-P151 WeakPolarHBondContact O-CG 3.23Å
142F97.6Very high97.1Very high1 Ų140.8 Ų40.80%0.00422%0.215CC..PPolyproline II helixtrans-103.8149.1173-175.3-99.7000111.4L91 L95 L135 H137 A139 D140 Y148 W150 P151 L162L91-F142 HydrophobicContact CD1-CE1 4.02Å; L91-F142 HydrophobicContact CD1-CZ 3.9Å; L91-F142 HydrophobicContact CD2-CE1 3.87Å; L91-F142 HydrophobicContact CD2-CE2 4.04Å; L91-F142 HydrophobicContact CD2-CZ 3.36Å; L91-F142 HydrophobicContact CG-CE1 4.21Å; L91-F142 HydrophobicContact CG-CZ 3.63Å; L95-F142 HydrophobicContact CD1-CE1 4Å; L95-F142 HydrophobicContact CD1-CE2 4.22Å; L95-F142 HydrophobicContact CD1-CZ 3.38Å; L135-F142 HydrophobicContact CD2-CE1 4.21Å; H137-F142 AromaticContact CE1-CD1 3.69Å; H137-F142 PolarHBondContact CE1-O 3.02Å; H137-F142 AromaticContact ND1-CD1 3.97Å; H137-F142 AromaticContact NE2-CD1 3.76Å; H137-F142 PolarHBondContact NE2-O 3.03Å; A139-F142 HydrophobicContact CB-CB 4.02Å; A139-F142 PolarHBondContact O-N 2.84Å; D140-F142 PolarHBondContact O-N 2.98Å; D140-F142 VanDerWaalsContact O-N 3.1Å; F142-Y148 HydrophobicContact CE2-CE2 4.11Å; F142-Y148 HydrophobicContact CZ-CE2 4.3Å; F142-W150 HydrophobicContact CD1-CZ3 4.41Å; F142-W150 AromaticContact CD2-CE3 3.93Å; F142-W150 HydrophobicContact CD2-CE3 3.93Å; F142-W150 AromaticContact CD2-CZ3 3.95Å; F142-W150 HydrophobicContact CD2-CZ3 3.95Å; F142-W150 HydrophobicContact CE2-CE3 4.02Å; F142-W150 HydrophobicContact CE2-CZ3 4.07Å; F142-W150 HydrophobicContact CG-CZ3 4.14Å; F142-W150 HydrophobicContact CZ-CZ3 4.35Å; F142-P151 HydrophobicContact CB-CG 3.81Å; F142-P151 HydrophobicContact CD2-CG 4.44Å; F142-L162 HydrophobicContact CD1-CD2 4.37Å; F142-L162 HydrophobicContact CE1-CD2 4.04Å
143P97.8Very high96.9Very high5 Ų542.3 Ų42.33%0.03223%0.231CC..SBendcis-74146.5-20.733-34.9000111.5L95 Y99 M111 V124L95-P143 HydrophobicContact CD1-CB 3.95Å; Y99-P143 WeakPolarHBondContact OH-CB 3.29Å; M111-P143 HydrophobicContact CE-CG 3.67Å; M111-P143 HydrophobicContact SD-CG 3.91Å; V124-P143 HydrophobicContact CG2-CG 3.82Å
144P97.1Very high96.8Very high39 Ų3946.6 Ų46.625%0.25325%0.251SS..PPolyproline II helixtrans-63.2144172.2-20.231.9000111.5Y99 R146 A149Y99-P144 WeakPolarHBondContact CE1-O 3.45Å; Y99-P144 PolarHBondContact OH-O 3.19Å; P144-R146 VanDerWaalsContact C-N 3.34Å; P144-R146 PolarHBondContact O-N 3.02Å; P144-A149 WeakPolarHBondContact CD-O 3.08Å; P144-A149 HydrophobicContact CG-CB 4.31Å; P144-A149 WeakPolarHBondContact CG-O 3.26Å
145K95.5Very high96.6Very high119 Ų11946.5 Ų46.552%0.51725%0.251SS..SBendtrans-68.3-22.7-171.4-61.1-177.6176.8-172.50115.5Y98 Y187 L188Y98-K145 PolarHBondContact OH-O 2.94Å; K145-Y187 PolarHBondContact NZ-O 2.86Å; K145-L188 HydrophobicContact CB-CD1 4.37Å; K145-L188 HydrophobicContact CD-CD1 4.09Å; K145-L188 HydrophobicContact CG-CD1 3.93Å
146R94.7Very high96.5Very high225 Ų22549.8 Ų49.885%0.84926%0.263SS*.SBendtrans-113.3-43.3-167.9-66.2-172.1178.8-159.5-0.5114.3Y99 P144Y99-R146 WeakPolarHBondContact CD1-O 3.4Å; P144-R146 VanDerWaalsContact C-N 3.34Å; P144-R146 PolarHBondContact O-N 3.02Å
147T96.8Very high96.4Very high102 Ų10252.1 Ų52.163%0.62628%0.276SS*.SBendtrans-139.3139.4-175.1-52.30000108.5Y99 A149Y99-T147 VanDerWaalsContact CE1-C 3.43Å; T147-A149 PolarHBondContact O-N 3.03Å
148Y98.1Very high96.4Very high32 Ų3254.4 Ų54.413%0.12529%0.286CS..  trans-59122.6172.9-175.3-90.9000110.2I84 Q89 L91 E92 L95 Y99 F142I84-Y148 WeakPolarHBondContact O-CE1 3.44Å; I84-Y148 PolarHBondContact O-OH 3.39Å; Q89-Y148 PolarHBondContact NE2-OH 2.96Å; L91-Y148 HydrophobicContact CG-CE2 4.35Å; E92-Y148 HydrophobicContact CB-CD1 3.98Å; E92-Y148 HydrophobicContact CB-CD2 3.99Å; E92-Y148 HydrophobicContact CB-CE1 3.74Å; E92-Y148 HydrophobicContact CB-CE2 3.75Å; E92-Y148 HydrophobicContact CB-CG 4.11Å; E92-Y148 HydrophobicContact CG-CD1 3.73Å; E92-Y148 HydrophobicContact CG-CD2 3.96Å; E92-Y148 HydrophobicContact CG-CE1 4.03Å; E92-Y148 HydrophobicContact CG-CE2 4.24Å; E92-Y148 HydrophobicContact CG-CG 3.7Å; L95-Y148 HydrophobicContact CD1-CD2 4.32Å; L95-Y148 HydrophobicContact CD1-CE2 4.1Å; Y99-Y148 HydrophobicContact CD2-CD2 4.48Å; Y99-Y148 AromaticContact CE2-CD2 3.82Å; Y99-Y148 HydrophobicContact CE2-CD2 3.82Å; Y99-Y148 HydrophobicContact CE2-CG 4.31Å; F142-Y148 HydrophobicContact CE2-CE2 4.11Å; F142-Y148 HydrophobicContact CZ-CE2 4.3Å
149A98Very high96.4Very high44 Ų4454.4 Ų54.436%0.36429%0.286SS..  trans-156.4150.4170.200000109P144 T147P144-A149 WeakPolarHBondContact CD-O 3.08Å; P144-A149 HydrophobicContact CG-CB 4.31Å; P144-A149 WeakPolarHBondContact CG-O 3.26Å; T147-A149 PolarHBondContact O-N 3.03Å
150W98.2Very high96.5Very high14 Ų1454.5 Ų54.55%0.05329%0.286CS..  trans-83.7128.4168.1-167.2-102.8000109.7K45 H63 I84 D85 L91 A139 F142 A155 Q160 L162K45-W150 HydrophobicContact CB-CZ2 4.44Å; K45-W150 HydrophobicContact CD-CZ2 3.9Å; K45-W150 HydrophobicContact CG-CZ2 3.87Å; H63-W150 AromaticContact ND1-CD1 3.88Å; I84-W150 HydrophobicContact CB-CD2 4.49Å; I84-W150 HydrophobicContact CB-CE3 4.44Å; I84-W150 HydrophobicContact CD1-CD2 4.28Å; I84-W150 HydrophobicContact CD1-CE3 3.77Å; I84-W150 HydrophobicContact CD1-CH2 3.64Å; I84-W150 HydrophobicContact CD1-CZ2 4.14Å; I84-W150 HydrophobicContact CD1-CZ3 3.43Å; I84-W150 VanDerWaalsContact CD1-CZ3 3.43Å; I84-W150 HydrophobicContact CG1-CD2 4.28Å; I84-W150 HydrophobicContact CG1-CE3 3.76Å; I84-W150 HydrophobicContact CG1-CZ3 3.92Å; I84-W150 HydrophobicContact CG2-CB 4.12Å; I84-W150 HydrophobicContact CG2-CD2 3.49Å; I84-W150 VanDerWaalsContact CG2-CD2 3.49Å; I84-W150 HydrophobicContact CG2-CE3 3.89Å; I84-W150 HydrophobicContact CG2-CG 3.59Å; D85-W150 HydrophobicContact CB-CB 3.8Å; L91-W150 HydrophobicContact CD2-CE3 4.31Å; L91-W150 HydrophobicContact CD2-CZ3 3.78Å; A139-W150 HydrophobicContact CB-CH2 3.64Å; A139-W150 HydrophobicContact CB-CZ2 3.93Å; A139-W150 HydrophobicContact CB-CZ3 4.46Å; F142-W150 HydrophobicContact CD1-CZ3 4.41Å; F142-W150 AromaticContact CD2-CE3 3.93Å; F142-W150 HydrophobicContact CD2-CE3 3.93Å; F142-W150 AromaticContact CD2-CZ3 3.95Å; F142-W150 HydrophobicContact CD2-CZ3 3.95Å; F142-W150 HydrophobicContact CE2-CE3 4.02Å; F142-W150 HydrophobicContact CE2-CZ3 4.07Å; F142-W150 HydrophobicContact CG-CZ3 4.14Å; F142-W150 HydrophobicContact CZ-CZ3 4.35Å; W150-A155 HydrophobicContact CZ2-CB 4.33Å; W150-A155 WeakPolarHBondContact CZ2-O 3.35Å; W150-A155 PolarHBondContact NE1-O 2.69Å; W150-Q160 HydrophobicContact CZ2-CB 4.43Å; W150-Q160 HydrophobicContact CZ2-CG 4.24Å; W150-L162 HydrophobicContact CH2-CD1 4.06Å; W150-L162 HydrophobicContact CH2-CD2 4.22Å; W150-L162 HydrophobicContact CZ3-CD2 4.18Å
151P97.2Very high96.7Very high15 Ų1551.9 Ų51.910%0.09727%0.272CS..  trans-66.1153.6-178.3-21.134000112.8D140 A141 F142 A155 R156D140-P151 WeakPolarHBondContact O-CB 3.39Å; D140-P151 WeakPolarHBondContact O-CG 3.32Å; A141-P151 HydrophobicContact CB-CB 4.12Å; A141-P151 HydrophobicContact CB-CG 4.25Å; A141-P151 WeakPolarHBondContact O-CG 3.23Å; F142-P151 HydrophobicContact CB-CG 3.81Å; F142-P151 HydrophobicContact CD2-CG 4.44Å; P151-A155 HydrophobicContact CB-CB 4.11Å; P151-A155 HydrophobicContact CG-CB 4.45Å; P151-R156 WeakPolarHBondContact O-CB 3.23Å
152N95.6Very high96.9Very high120 Ų12048.5 Ų48.564%0.64224%0.244SC*.SBendtrans-79-179.1168.6-70.4-53.5000111.3R156N152-R156 PolarHBondContact OD1-NH1 3.2Å; N152-R156 VanDerWaalsContact OD1-NH1 3.15Å
153G95Very high97Very high32 Ų3248.5 Ų48.533%0.3324%0.244SC..THydrogen-bonded Turntrans74.4-143.1179.200000111.3A155 R156 D157G153-A155 VanDerWaalsContact C-N 3.28Å; G153-A155 PolarHBondContact O-N 3.46Å; G153-R156 CarbonylContact O-C 3.57Å; G153-R156 WeakPolarHBondContact O-CA 3.15Å; G153-R156 WeakPolarHBondContact O-CB 3.25Å; G153-R156 PolarHBondContact O-N 2.8Å; G153-D157 PolarHBondContact O-N 3.2Å
154E94.7Very high97Very high90 Ų9048.2 Ų48.242%0.42124%0.243SC..Hα-helixtrans-56.2-38.8-172.8-64.6-69.7-168.400113.6R156 D157 K158 Q160E154-R156 PolarHBondContact O-N 2.92Å; E154-D157 PolarHBondContact O-N 3.14Å; E154-K158 WeakPolarHBondContact O-CB 3.46Å; E154-K158 PolarHBondContact O-N 2.9Å; E154-K158 IonicContact OE1-NZ 3.85Å; E154-K158 PolarHBondContact OE1-NZ 2.87Å; E154-K158 WeakPolarHBondContact OE2-CD 3.43Å; E154-K158 WeakPolarHBondContact OE2-CE 3.24Å; E154-K158 VanDerWaalsContact OE2-CG 3.23Å; E154-K158 WeakPolarHBondContact OE2-CG 3.32Å; E154-K158 IonicContact OE2-NZ 2.69Å; E154-K158 PolarHBondContact OE2-NZ 2.84Å; E154-Q160 PolarHBondContact O-NE2 2.95Å
155A96.2Very high97.1Very high1 Ų146.5 Ų46.51%0.00823%0.231CC..Hα-helixtrans-57.9-33.8175.500000112.5K45 A139 W150 P151 G153K45-A155 WeakPolarHBondContact CD-O 3.35Å; K45-A155 WeakPolarHBondContact CE-O 3.44Å; K45-A155 PolarHBondContact NZ-O 2.91Å; A139-A155 HydrophobicContact CB-CB 4.08Å; W150-A155 HydrophobicContact CZ2-CB 4.33Å; W150-A155 WeakPolarHBondContact CZ2-O 3.35Å; W150-A155 PolarHBondContact NE1-O 2.69Å; P151-A155 HydrophobicContact CB-CB 4.11Å; P151-A155 HydrophobicContact CG-CB 4.45Å; G153-A155 VanDerWaalsContact C-N 3.28Å; G153-A155 PolarHBondContact O-N 3.46Å
156R96.9Very high97.2Very high68 Ų6840.8 Ų40.826%0.25721%0.207SC..Hα-helixtrans-89.8-33.9176.9-170.6-168.968.3-173.8-0.4112.9K45 G62 P151 N152 G153 E154K45-R156 PolarHBondContact NZ-O 3.04Å; G62-R156 WeakPolarHBondContact CA-O 3.23Å; P151-R156 WeakPolarHBondContact O-CB 3.23Å; N152-R156 PolarHBondContact OD1-NH1 3.2Å; N152-R156 VanDerWaalsContact OD1-NH1 3.15Å; G153-R156 CarbonylContact O-C 3.57Å; G153-R156 WeakPolarHBondContact O-CA 3.15Å; G153-R156 WeakPolarHBondContact O-CB 3.25Å; G153-R156 PolarHBondContact O-N 2.8Å; E154-R156 PolarHBondContact O-N 2.92Å
157D96.4Very high97.4Very high60 Ų6030.1 Ų30.132%0.32117%0.166SC..Hα-helixtrans-90.5-29.6-170-60.2-24.4000111.9A47 K48 G153 E154A47-D157 WeakPolarHBondContact CA-O 3.48Å; K48-D157 PolarHBondContact N-O 3.41Å; G153-D157 PolarHBondContact O-N 3.2Å; E154-D157 PolarHBondContact O-N 3.14Å
158K96.8Very high97.4Very high47 Ų4728 Ų2820%0.20415%0.151CC..SBendtrans-104.7161.4176.5-71.6-174.8-179.3136.70113.7K45 E154 T300 D302K45-K158 PolarHBondContact NZ-O 3.04Å; E154-K158 WeakPolarHBondContact O-CB 3.46Å; E154-K158 PolarHBondContact O-N 2.9Å; E154-K158 IonicContact OE1-NZ 3.85Å; E154-K158 PolarHBondContact OE1-NZ 2.87Å; E154-K158 WeakPolarHBondContact OE2-CD 3.43Å; E154-K158 WeakPolarHBondContact OE2-CE 3.24Å; E154-K158 VanDerWaalsContact OE2-CG 3.23Å; E154-K158 WeakPolarHBondContact OE2-CG 3.32Å; E154-K158 IonicContact OE2-NZ 2.69Å; E154-K158 PolarHBondContact OE2-NZ 2.84Å; K158-T300 CarbonylContact C-O 3.54Å; K158-T300 VanDerWaalsContact CA-O 3.27Å; K158-T300 WeakPolarHBondContact CA-O 3.45Å; K158-T300 VanDerWaalsContact CB-O 3.31Å; K158-T300 WeakPolarHBondContact CB-O 3.2Å; K158-D302 VanDerWaalsContact CD-OD2 3.26Å; K158-D302 WeakPolarHBondContact CD-OD2 3.47Å
159A97.7Very high97.4Very high2 Ų227.8 Ų27.82%0.01715%0.154CC..BIsolated β-bridgetrans-71.2142.3171.800000110.8Y44 K45 A47 T300 D301 D302Y44-A159 HydrophobicContact CE1-CB 4.05Å; K45-A159 CarbonylContact O-C 3.55Å; K45-A159 WeakPolarHBondContact O-CA 3.45Å; K45-A159 VanDerWaalsContact O-CB 3.32Å; K45-A159 WeakPolarHBondContact O-CB 3.25Å; A47-A159 HydrophobicContact CB-CB 4.35Å; A159-T300 PolarHBondContact N-O 3.38Å; A159-D301 HydrophobicContact CB-CB 3.95Å; A159-D302 PolarHBondContact O-N 3.49Å
160Q97.9Very high97.3Very high2 Ų230.2 Ų30.21%0.00917%0.168CC..EExtended strand (participates in β ladder)trans-136.3144.6-173.4-54.8-60.9-41.800108.3K45 D138 A139 W150 E154 D302K45-Q160 HydrophobicContact CB-CB 4.21Å; K45-Q160 HydrophobicContact CD-CB 4.15Å; K45-Q160 HydrophobicContact CD-CG 3.99Å; K45-Q160 PolarHBondContact N-O 3.2Å; K45-Q160 PolarHBondContact O-N 3.19Å; D138-Q160 VanDerWaalsContact C-OE1 3.29Å; D138-Q160 VanDerWaalsContact CG-OE1 3.29Å; D138-Q160 PolarHBondContact O-OE1 2.88Å; D138-Q160 VanDerWaalsContact OD1-CA 3.25Å; D138-Q160 WeakPolarHBondContact OD1-CA 3.49Å; D138-Q160 WeakPolarHBondContact OD1-CB 3.44Å; D138-Q160 PolarHBondContact OD1-OE1 2.96Å; A139-Q160 HydrophobicContact CB-CB 4.4Å; A139-Q160 HydrophobicContact CB-CG 4.22Å; W150-Q160 HydrophobicContact CZ2-CB 4.43Å; W150-Q160 HydrophobicContact CZ2-CG 4.24Å; E154-Q160 PolarHBondContact O-NE2 2.95Å; Q160-D302 PolarHBondContact NE2-OD2 3.39Å
161L98.4Very high97.3Very high0 Ų030.1 Ų30.10%017%0.169CC..EExtended strand (participates in β ladder)trans-114.4127.9177.617970.7000110.1L42 Y44 H137 D138 S303 W305 W316 Y318L42-L161 HydrophobicContact CD1-CD1 4.09Å; L42-L161 HydrophobicContact CD2-CD1 3.33Å; L42-L161 HydrophobicContact CG-CD1 3.73Å; Y44-L161 HydrophobicContact CD2-CD1 4.09Å; H137-L161 WeakPolarHBondContact CA-O 3.45Å; D138-L161 VanDerWaalsContact CG-N 3.33Å; D138-L161 PolarHBondContact OD1-N 3.07Å; D138-L161 PolarHBondContact OD2-N 3.19Å; L161-S303 VanDerWaalsContact CB-CB 3.41Å; L161-W305 HydrophobicContact CD2-CB 4.19Å; L161-W305 HydrophobicContact CD2-CG 4.42Å; L161-W316 HydrophobicContact CD1-CZ2 4.48Å; L161-W316 HydrophobicContact CD2-CH2 4.14Å; L161-W316 HydrophobicContact CD2-CZ2 3.85Å; L161-Y318 HydrophobicContact CD2-CD2 3.66Å; L161-Y318 HydrophobicContact CD2-CE2 4.13Å; L161-Y318 HydrophobicContact CG-CD2 4.09Å; L161-Y318 HydrophobicContact CG-CE2 4.29Å
162L98.8Very high97.3Very high0 Ų029.4 Ų29.40%017%0.165CC..EExtended strand (participates in β ladder)trans-121.9130.8175-51.991.2000109.6L42 I43 K45 I84 L91 L135 L136 H137 F142 W150L42-L162 CarbonylContact C-O 3.32Å; L42-L162 VanDerWaalsContact CA-O 3.29Å; L42-L162 WeakPolarHBondContact CA-O 3.19Å; I43-L162 HydrophobicContact CB-CB 4.24Å; I43-L162 HydrophobicContact CB-CD1 4.06Å; I43-L162 HydrophobicContact CG2-CD1 3.83Å; I43-L162 PolarHBondContact N-O 2.94Å; I43-L162 PolarHBondContact O-N 3.15Å; K45-L162 HydrophobicContact CB-CD1 4.39Å; I84-L162 HydrophobicContact CD1-CD1 4.24Å; L91-L162 HydrophobicContact CD1-CD2 3.99Å; L91-L162 HydrophobicContact CD2-CD2 3.64Å; L91-L162 HydrophobicContact CG-CD2 4.48Å; L135-L162 HydrophobicContact CD1-CB 4.21Å; L136-L162 CarbonylContact O-C 3.27Å; L136-L162 VanDerWaalsContact O-CA 3.32Å; L136-L162 WeakPolarHBondContact O-CA 3.13Å; H137-L162 HydrophobicContact CB-CB 4.18Å; H137-L162 HydrophobicContact CB-CD2 3.87Å; H137-L162 HydrophobicContact CB-CG 3.69Å; F142-L162 HydrophobicContact CD1-CD2 4.37Å; F142-L162 HydrophobicContact CE1-CD2 4.04Å; W150-L162 HydrophobicContact CH2-CD1 4.06Å; W150-L162 HydrophobicContact CH2-CD2 4.22Å; W150-L162 HydrophobicContact CZ3-CD2 4.18Å
163F98.8Very high97.4Very high1 Ų127.7 Ų27.70%0.00415%0.153CC..EExtended strand (participates in β ladder)trans-126.7117.2178.9180-135.5000110W40 F41 L42 L135 L136 V165 W316 Y318 V335 I337W40-F163 HydrophobicContact CB-CE2 4.09Å; F41-F163 WeakPolarHBondContact O-CD2 3.31Å; L42-F163 HydrophobicContact CB-CD2 4.42Å; L135-F163 CarbonylContact C-O 3.6Å; L135-F163 WeakPolarHBondContact CA-O 3.36Å; L136-F163 HydrophobicContact CD1-CD1 4.39Å; L136-F163 PolarHBondContact N-O 2.86Å; L136-F163 PolarHBondContact O-N 2.91Å; F163-V165 HydrophobicContact CD1-CG2 4.18Å; F163-V165 HydrophobicContact CD2-CG2 4.43Å; F163-V165 HydrophobicContact CE1-CG2 3.52Å; F163-V165 HydrophobicContact CE2-CG2 3.81Å; F163-V165 HydrophobicContact CZ-CG2 3.31Å; F163-W316 HydrophobicContact CB-CH2 4.4Å; F163-W316 HydrophobicContact CD1-CZ3 4.01Å; F163-W316 HydrophobicContact CD2-CZ3 4.1Å; F163-W316 HydrophobicContact CE1-CZ3 4.16Å; F163-W316 HydrophobicContact CE2-CZ3 4.25Å; F163-W316 HydrophobicContact CG-CH2 4.28Å; F163-W316 AromaticContact CG-CZ3 3.99Å; F163-W316 HydrophobicContact CG-CZ3 3.99Å; F163-W316 HydrophobicContact CZ-CZ3 4.28Å; F163-Y318 HydrophobicContact CB-CD2 4.26Å; F163-V335 HydrophobicContact CE1-CG1 3.99Å; F163-I337 HydrophobicContact CZ-CB 4.46Å; F163-I337 HydrophobicContact CZ-CD1 4.39Å; F163-I337 HydrophobicContact CZ-CG2 4.38Å
164C98.9Very high97.6Very high0 Ų029.6 Ų29.60%015%0.153CC..EExtended strand (participates in β ladder)trans-111134.6178.7-171.40000109.9C29 W40 F41 W134 L135C29-C164 HydrophobicContact CB-CB 3.93Å; C29-C164 WeakPolarHBondContact CB-SG 3.4Å; C29-C164 WeakPolarHBondContact SG-CB 3.16Å; C29-C164 CovalentContact SG-SG 2.04Å; C29-C164 PolarHBondContact SG-SG 2.82Å; W40-C164 CarbonylContact C-O 3.54Å; W40-C164 WeakPolarHBondContact CA-O 3.16Å; W40-C164 VanDerWaalsContact CB-O 3.26Å; W40-C164 WeakPolarHBondContact CB-O 3.42Å; F41-C164 HydrophobicContact CD1-CB 3.74Å; F41-C164 HydrophobicContact CD2-CB 3.99Å; F41-C164 HydrophobicContact CE1-CB 3.31Å; F41-C164 VanDerWaalsContact CE1-SG 3.57Å; F41-C164 HydrophobicContact CE2-CB 3.62Å; F41-C164 HydrophobicContact CG-CB 4.03Å; F41-C164 HydrophobicContact CZ-CB 3.25Å; F41-C164 PolarHBondContact N-O 3.26Å; F41-C164 PolarHBondContact O-N 2.83Å; W134-C164 CarbonylContact O-C 3.49Å; W134-C164 WeakPolarHBondContact O-CA 3.5Å; L135-C164 HydrophobicContact CD1-CB 3.87Å
165V98.7Very high97.7Very high2 Ų225.3 Ų25.31%0.01213%0.133CC..EExtended strand (participates in β ladder)trans-127.9128.8172.9-171.40000110.5C29 W40 F133 W134 F163 F167 T222 V233C29-V165 VanDerWaalsContact SG-CA 3.57Å; C29-V165 PolarHBondContact SG-N 2.86Å; W40-V165 HydrophobicContact CB-CG2 4.31Å; F133-V165 CarbonylContact C-O 3.08Å; F133-V165 WeakPolarHBondContact CA-O 3.29Å; W134-V165 PolarHBondContact N-O 3.12Å; W134-V165 PolarHBondContact O-N 2.85Å; F163-V165 HydrophobicContact CD1-CG2 4.18Å; F163-V165 HydrophobicContact CD2-CG2 4.43Å; F163-V165 HydrophobicContact CE1-CG2 3.52Å; F163-V165 HydrophobicContact CE2-CG2 3.81Å; F163-V165 HydrophobicContact CZ-CG2 3.31Å; V165-F167 HydrophobicContact CB-CD2 4.27Å; V165-F167 HydrophobicContact CB-CE2 3.55Å; V165-F167 HydrophobicContact CB-CZ 3.87Å; V165-F167 HydrophobicContact CG1-CD1 4.5Å; V165-F167 HydrophobicContact CG1-CD2 4.09Å; V165-F167 HydrophobicContact CG1-CE1 3.9Å; V165-F167 HydrophobicContact CG1-CE2 3.45Å; V165-F167 VanDerWaalsContact CG1-CE2 3.45Å; V165-F167 HydrophobicContact CG1-CZ 3.33Å; V165-T222 HydrophobicContact CG1-CG2 3.67Å; V165-V233 HydrophobicContact CG1-CG2 4.25Å
166S98.2Very high97.8Very high0 Ų025.2 Ų25.20%013%0.133CC..EExtended strand (participates in β ladder)trans-84.4134.6173.2-62.70000109.8C29 V38 Q39 A132 T222 K223C29-S166 WeakPolarHBondContact CB-OG 3.41Å; C29-S166 PolarHBondContact N-OG 2.83Å; C29-S166 PolarHBondContact SG-N 2.86Å; C29-S166 VanDerWaalsContact SG-N 3.39Å; V38-S166 WeakPolarHBondContact O-CB 3.18Å; V38-S166 PolarHBondContact O-OG 3.21Å; Q39-S166 PolarHBondContact O-N 2.82Å; A132-S166 CarbonylContact O-C 3.6Å; A132-S166 WeakPolarHBondContact O-CA 3.33Å; S166-T222 CarbonylContact O-C 3.59Å; S166-T222 WeakPolarHBondContact O-CA 3.25Å; S166-K223 PolarHBondContact O-N 3.17Å
167F98.2Very high97.8Very high0 Ų026.4 Ų26.40%014%0.137CC..EExtended strand (participates in β ladder)trans-130.6159-179.3-70.9-72.5000111.6A132 W134 V165 I175 L220 T221 V233A132-F167 HydrophobicContact CB-CB 4.41Å; A132-F167 PolarHBondContact N-O 3.12Å; A132-F167 PolarHBondContact O-N 3.12Å; W134-F167 HydrophobicContact CB-CD2 4.25Å; W134-F167 HydrophobicContact CB-CE2 4.1Å; W134-F167 HydrophobicContact CE3-CE2 4.11Å; V165-F167 HydrophobicContact CB-CD2 4.27Å; V165-F167 HydrophobicContact CB-CE2 3.55Å; V165-F167 HydrophobicContact CB-CZ 3.87Å; V165-F167 HydrophobicContact CG1-CD1 4.5Å; V165-F167 HydrophobicContact CG1-CD2 4.09Å; V165-F167 HydrophobicContact CG1-CE1 3.9Å; V165-F167 HydrophobicContact CG1-CE2 3.45Å; V165-F167 VanDerWaalsContact CG1-CE2 3.45Å; V165-F167 HydrophobicContact CG1-CZ 3.33Å; F167-I175 HydrophobicContact CD2-CD1 3.81Å; F167-I175 HydrophobicContact CE2-CD1 3.9Å; F167-I175 HydrophobicContact CG-CD1 4.25Å; F167-I175 HydrophobicContact CZ-CD1 4.44Å; F167-L220 HydrophobicContact CE1-CB 3.84Å; F167-L220 HydrophobicContact CE1-CD1 4.4Å; F167-L220 HydrophobicContact CZ-CB 4.31Å; F167-L220 HydrophobicContact CZ-CD1 4.14Å; F167-T221 VanDerWaalsContact CD1-O 3.24Å; F167-T221 WeakPolarHBondContact CD1-O 3.24Å; F167-V233 HydrophobicContact CZ-CB 4.49Å; F167-V233 HydrophobicContact CZ-CG1 4.44Å
168D97.1Very high97.8Very high59 Ų5923.6 Ų23.632%0.31612%0.122SC..  trans-73.3141.9157.8-68.8-59.8000109.1S170 S171 K223D168-S170 PolarHBondContact O-N 3.33Å; D168-S171 WeakPolarHBondContact O-CB 3.15Å; D168-S171 PolarHBondContact O-N 3.23Å; D168-S171 PolarHBondContact O-OG 3.25Å; D168-K223 IonicContact OD1-NZ 2.74Å; D168-K223 PolarHBondContact OD1-NZ 3.15Å
169P96.8Very high97.8Very high27 Ų2721.3 Ų21.318%0.17511%0.112CC..G310 helixtrans-54.8-24.2-179-30.237.7000114.6N128 S171 L172N128-P169 WeakPolarHBondContact O-CG 3.28Å; P169-S171 PolarHBondContact O-N 2.86Å; P169-S171 VanDerWaalsContact O-N 3.15Å; P169-L172 HydrophobicContact CB-CD1 4.01Å; P169-L172 VanDerWaalsContact O-CB 3.23Å; P169-L172 WeakPolarHBondContact O-CB 3.47Å; P169-L172 WeakPolarHBondContact O-CD1 3.35Å; P169-L172 VanDerWaalsContact O-CG 3.25Å; P169-L172 WeakPolarHBondContact O-CG 3.49Å; P169-L172 PolarHBondContact O-N 3.2Å
170S96.2Very high97.6Very high94 Ų9422.7 Ų22.766%0.65712%0.117SC*.G310 helixtrans-59.3-22.3173.259.50000114.2D168 L172D168-S170 PolarHBondContact O-N 3.33Å; S170-L172 VanDerWaalsContact C-N 3.34Å
171S97.9Very high97.4Very high12 Ų1223.2 Ų23.28%0.08412%0.119CC..G310 helixtrans-77-20.5176.2-59.80000112.9D168 P169 Q173 Q174 I175D168-S171 WeakPolarHBondContact O-CB 3.15Å; D168-S171 PolarHBondContact O-N 3.23Å; D168-S171 PolarHBondContact O-OG 3.25Å; P169-S171 PolarHBondContact O-N 2.86Å; P169-S171 VanDerWaalsContact O-N 3.15Å; S171-Q173 VanDerWaalsContact C-N 3.28Å; S171-Q173 PolarHBondContact O-N 2.88Å; S171-Q174 PolarHBondContact O-N 2.57Å; S171-Q174 VanDerWaalsContact O-N 3.11Å; S171-I175 WeakPolarHBondContact O-CG1 3.18Å; S171-I175 PolarHBondContact O-N 2.88Å
172L98.2Very high97.1Very high0 Ų023.6 Ų23.60%012%0.12CC..Hα-helixtrans-61.1-35.5-173.1-66.7170000112.9L108 L125 S127 A132 P169 S170 Q174 I175 A176 F195 Y200L108-L172 HydrophobicContact CD2-CD1 3.95Å; L108-L172 HydrophobicContact CD2-CD2 4.32Å; L125-L172 HydrophobicContact CD1-CD2 3.56Å; L125-L172 HydrophobicContact CD2-CD2 3.8Å; L125-L172 HydrophobicContact CG-CD2 3.71Å; S127-L172 VanDerWaalsContact CB-CD1 3.49Å; S127-L172 WeakPolarHBondContact OG-CD1 3.46Å; A132-L172 HydrophobicContact CB-CD1 4.11Å; A132-L172 HydrophobicContact CB-CD2 3.88Å; A132-L172 HydrophobicContact CB-CG 4.13Å; P169-L172 HydrophobicContact CB-CD1 4.01Å; P169-L172 VanDerWaalsContact O-CB 3.23Å; P169-L172 WeakPolarHBondContact O-CB 3.47Å; P169-L172 WeakPolarHBondContact O-CD1 3.35Å; P169-L172 VanDerWaalsContact O-CG 3.25Å; P169-L172 WeakPolarHBondContact O-CG 3.49Å; P169-L172 PolarHBondContact O-N 3.2Å; S170-L172 VanDerWaalsContact C-N 3.34Å; L172-Q174 VanDerWaalsContact C-N 3.28Å; L172-Q174 PolarHBondContact O-N 2.99Å; L172-I175 PolarHBondContact O-N 2.87Å; L172-A176 WeakPolarHBondContact O-CB 3.47Å; L172-A176 PolarHBondContact O-N 2.56Å; L172-F195 HydrophobicContact CB-CE1 4.44Å; L172-F195 HydrophobicContact CD1-CE1 3.72Å; L172-F195 HydrophobicContact CD1-CZ 3.83Å; L172-Y200 HydrophobicContact CB-CE1 4.21Å; L172-Y200 VanDerWaalsContact CB-OH 3.25Å; L172-Y200 WeakPolarHBondContact CB-OH 3.18Å
173Q97.9Very high96.8Very high84 Ų8428.8 Ų28.839%0.39314%0.14SC..Hα-helixtrans-64-39.6-179.9-166.7-172.348.700110.7S171 R177 P199 Y200S171-Q173 VanDerWaalsContact C-N 3.28Å; S171-Q173 PolarHBondContact O-N 2.88Å; Q173-R177 VanDerWaalsContact O-CB 3.28Å; Q173-R177 WeakPolarHBondContact O-CB 3.27Å; Q173-R177 PolarHBondContact O-N 2.95Å; Q173-P199 HydrophobicContact CG-CG 4.29Å; Q173-Y200 VanDerWaalsContact CA-OH 3.28Å; Q173-Y200 WeakPolarHBondContact CA-OH 3.24Å; Q173-Y200 PolarHBondContact N-OH 3.41Å
174Q98.2Very high96.5Very high72 Ų7229 Ų2934%0.33614%0.141SC..Hα-helixtrans-72.3-38.6178.4-67.4-178.198.400111.5S171 L172 T178 Q218 L220S171-Q174 PolarHBondContact O-N 2.57Å; S171-Q174 VanDerWaalsContact O-N 3.11Å; L172-Q174 VanDerWaalsContact C-N 3.28Å; L172-Q174 PolarHBondContact O-N 2.99Å; Q174-T178 WeakPolarHBondContact O-CB 3.49Å; Q174-T178 PolarHBondContact O-N 2.98Å; Q174-T178 PolarHBondContact O-OG1 2.89Å; Q174-Q218 HydrophobicContact CB-CG 4.01Å; Q174-L220 HydrophobicContact CB-CD2 3.94Å
175I98.5Very high96.4Very high0 Ų036.1 Ų36.10%017%0.168CC..Hα-helixtrans-61.4-54.1173.2-67167.6000109.8L125 W134 F167 S171 L172 R177 T178 L179 L220L125-I175 HydrophobicContact CD1-CG2 4.29Å; L125-I175 HydrophobicContact CD2-CG2 4.3Å; W134-I175 HydrophobicContact CD2-CG2 4.14Å; W134-I175 HydrophobicContact CE3-CD1 4.2Å; W134-I175 HydrophobicContact CE3-CG1 4.37Å; W134-I175 HydrophobicContact CE3-CG2 4.2Å; W134-I175 HydrophobicContact CH2-CG2 4.49Å; W134-I175 HydrophobicContact CZ2-CG2 4.41Å; W134-I175 HydrophobicContact CZ3-CG2 4.38Å; F167-I175 HydrophobicContact CD2-CD1 3.81Å; F167-I175 HydrophobicContact CE2-CD1 3.9Å; F167-I175 HydrophobicContact CG-CD1 4.25Å; F167-I175 HydrophobicContact CZ-CD1 4.44Å; S171-I175 WeakPolarHBondContact O-CG1 3.18Å; S171-I175 PolarHBondContact O-N 2.88Å; L172-I175 PolarHBondContact O-N 2.87Å; I175-R177 PolarHBondContact O-N 3.05Å; I175-T178 PolarHBondContact O-N 2.82Å; I175-T178 VanDerWaalsContact O-N 3.13Å; I175-L179 VanDerWaalsContact O-CB 3.26Å; I175-L179 WeakPolarHBondContact O-CB 3.21Å; I175-L179 PolarHBondContact O-N 2.82Å; I175-L220 HydrophobicContact CD1-CD1 4.33Å; I175-L220 HydrophobicContact CG1-CD1 3.71Å; I175-L220 HydrophobicContact CG1-CD2 4.13Å
176A97.7Very high96.3Very high0 Ų036.6 Ų36.60%017%0.171CC..Hα-helixtrans-61.2-42.9-178.600000112.3L172 T178 L179 R180 P199 Y200 L203L172-A176 WeakPolarHBondContact O-CB 3.47Å; L172-A176 PolarHBondContact O-N 2.56Å; A176-T178 VanDerWaalsContact C-N 3.3Å; A176-T178 PolarHBondContact O-N 2.98Å; A176-L179 PolarHBondContact O-N 3.15Å; A176-R180 WeakPolarHBondContact O-CG 3.49Å; A176-R180 PolarHBondContact O-N 3.34Å; A176-R180 VanDerWaalsContact O-N 3.15Å; A176-P199 HydrophobicContact CB-CG 3.78Å; A176-Y200 HydrophobicContact CB-CD1 3.5Å; A176-Y200 HydrophobicContact CB-CE1 3.47Å; A176-Y200 VanDerWaalsContact CB-CE1 3.47Å; A176-Y200 HydrophobicContact CB-CG 4.48Å; A176-L203 HydrophobicContact CB-CD2 3.99Å
177R96Very high96.1Very high93 Ų9338.9 Ų38.935%0.35118%0.18SC..Hα-helixtrans-59.8-41.4175.2-174.1175.6-70.4148.70.1112Q173 I175 P199Q173-R177 VanDerWaalsContact O-CB 3.28Å; Q173-R177 WeakPolarHBondContact O-CB 3.27Å; Q173-R177 PolarHBondContact O-N 2.95Å; I175-R177 PolarHBondContact O-N 3.05Å; R177-P199 HydrophobicContact CB-CB 4.26Å; R177-P199 HydrophobicContact CB-CG 3.98Å
178T96.9Very high96Very high0 Ų040.3 Ų40.30%019%0.188CC..Hα-helixtrans-74-40.3-179.2-52.20000111.1Q174 I175 A176 R180 Y181 R216 Q218 Y235 T237Q174-T178 WeakPolarHBondContact O-CB 3.49Å; Q174-T178 PolarHBondContact O-N 2.98Å; Q174-T178 PolarHBondContact O-OG1 2.89Å; I175-T178 PolarHBondContact O-N 2.82Å; I175-T178 VanDerWaalsContact O-N 3.13Å; A176-T178 VanDerWaalsContact C-N 3.3Å; A176-T178 PolarHBondContact O-N 2.98Å; T178-R180 PolarHBondContact O-N 2.96Å; T178-Y181 VanDerWaalsContact O-CB 3.27Å; T178-Y181 WeakPolarHBondContact O-CB 3.05Å; T178-Y181 PolarHBondContact O-N 3.24Å; T178-R216 HydrophobicContact CG2-CG 4.09Å; T178-R216 PolarHBondContact OG1-NE 3.21Å; T178-Q218 HydrophobicContact CG2-CB 4.1Å; T178-Q218 WeakPolarHBondContact OG1-CB 3.28Å; T178-Q218 WeakPolarHBondContact OG1-CG 3.32Å; T178-Y235 VanDerWaalsContact CB-CE1 3.48Å; T178-Y235 HydrophobicContact CG2-CD1 3.31Å; T178-Y235 HydrophobicContact CG2-CD2 4.11Å; T178-Y235 HydrophobicContact CG2-CE1 3.43Å; T178-Y235 VanDerWaalsContact CG2-CE1 3.43Å; T178-Y235 HydrophobicContact CG2-CE2 4.21Å; T178-Y235 HydrophobicContact CG2-CG 3.67Å; T178-T237 HydrophobicContact CG2-CG2 3.61Å
179L96.3Very high96Very high0 Ų042 Ų420%019%0.194CC..Hα-helixtrans-59.4-32.6177177.158.2000113.1Y112 I175 A176 Y181 E182 P184 L203 Y235Y112-L179 HydrophobicContact CD1-CD2 3.87Å; Y112-L179 HydrophobicContact CD2-CD1 3.95Å; Y112-L179 HydrophobicContact CD2-CD2 4.29Å; Y112-L179 HydrophobicContact CE1-CD1 4.37Å; Y112-L179 HydrophobicContact CE1-CD2 3.57Å; Y112-L179 HydrophobicContact CE2-CD1 3.38Å; Y112-L179 HydrophobicContact CE2-CD2 4.06Å; Y112-L179 HydrophobicContact CE2-CG 4.37Å; Y112-L179 HydrophobicContact CG-CD2 4.19Å; I175-L179 VanDerWaalsContact O-CB 3.26Å; I175-L179 WeakPolarHBondContact O-CB 3.21Å; I175-L179 PolarHBondContact O-N 2.82Å; A176-L179 PolarHBondContact O-N 3.15Å; L179-Y181 PolarHBondContact O-N 3.24Å; L179-Y181 VanDerWaalsContact O-N 3.11Å; L179-E182 HydrophobicContact CD1-CB 4.38Å; L179-E182 HydrophobicContact CD1-CG 4.47Å; L179-E182 WeakPolarHBondContact O-CB 3.49Å; L179-E182 PolarHBondContact O-N 2.82Å; L179-P184 HydrophobicContact CD1-CB 4.26Å; L179-P184 HydrophobicContact CD1-CG 3.91Å; L179-P184 HydrophobicContact CD2-CG 4.45Å; L179-P184 HydrophobicContact CG-CG 3.89Å; L179-P184 VanDerWaalsContact O-CD 3.3Å; L179-P184 WeakPolarHBondContact O-CD 3.43Å; L179-L203 HydrophobicContact CB-CD1 4.49Å; L179-L203 HydrophobicContact CD2-CD1 4.1Å; L179-L203 HydrophobicContact CD2-CD2 3.94Å; L179-L203 HydrophobicContact CG-CD1 3.94Å; L179-Y235 VanDerWaalsContact CA-OH 3.27Å; L179-Y235 WeakPolarHBondContact CA-OH 3.36Å; L179-Y235 HydrophobicContact CB-CE1 4.43Å
180R94.5Very high95.9Very high31 Ų3143.9 Ų43.912%0.11720%0.198CC..G310 helixtrans-56.5-26.4173.1-71.2-177.665.7-168.81113.5A176 T178 E182 R183 L203 E207 L209A176-R180 WeakPolarHBondContact O-CG 3.49Å; A176-R180 PolarHBondContact O-N 3.34Å; A176-R180 VanDerWaalsContact O-N 3.15Å; T178-R180 PolarHBondContact O-N 2.96Å; R180-E182 PolarHBondContact O-N 2.71Å; R180-R183 PolarHBondContact O-N 2.8Å; R180-R183 VanDerWaalsContact O-N 3.15Å; R180-L203 HydrophobicContact CG-CB 3.88Å; R180-L203 HydrophobicContact CG-CD1 3.88Å; R180-L203 HydrophobicContact CG-CG 4.46Å; R180-E207 PolarHBondContact NH2-O 2.94Å; R180-L209 HydrophobicContact CB-CD1 3.57Å; R180-L209 HydrophobicContact CB-CG 4.46Å; R180-L209 VanDerWaalsContact CZ-CD2 3.47Å
181Y93.1Very high96Very high12 Ų1240.2 Ų40.25%0.04717%0.171CC..G310 helixtrans-67.3-24.1176.2-76.4-116.1000112.6T178 L179 R183 L209 Q212 M213 R216 T237 R239T178-Y181 VanDerWaalsContact O-CB 3.27Å; T178-Y181 WeakPolarHBondContact O-CB 3.05Å; T178-Y181 PolarHBondContact O-N 3.24Å; L179-Y181 PolarHBondContact O-N 3.24Å; L179-Y181 VanDerWaalsContact O-N 3.11Å; Y181-R183 VanDerWaalsContact C-N 3.28Å; Y181-L209 HydrophobicContact CD2-CD1 4.16Å; Y181-L209 HydrophobicContact CE2-CD1 4.42Å; Y181-Q212 HydrophobicContact CE1-CB 4.07Å; Y181-Q212 VanDerWaalsContact CZ-CD 3.41Å; Y181-Q212 VanDerWaalsContact OH-CD 3.24Å; Y181-Q212 PolarHBondContact OH-OE1 3.32Å; Y181-M213 WeakPolarHBondContact CE1-O 3.49Å; Y181-R216 HydrophobicContact CD1-CB 3.83Å; Y181-R216 HydrophobicContact CD2-CB 4.34Å; Y181-R216 HydrophobicContact CE1-CB 3.58Å; Y181-R216 HydrophobicContact CE2-CB 4.14Å; Y181-R216 HydrophobicContact CE2-CG 4.3Å; Y181-R216 HydrophobicContact CG-CB 4.2Å; Y181-T237 VanDerWaalsContact CB-OG1 3.3Å; Y181-T237 WeakPolarHBondContact CB-OG1 3.37Å; Y181-R239 HydrophobicContact CD1-CG 4.06Å
182E92.1Very high95.8Very high8 Ų839.8 Ų39.84%0.03717%0.168CC..G310 helixtrans-82.3-5.5175.9-56.4-171.2-146.500113.3T114 L179 R180 P184 Y235 T237 N320 S333T114-E182 HydrophobicContact CG2-CB 3.77Å; T114-E182 WeakPolarHBondContact CG2-OE2 3.11Å; L179-E182 HydrophobicContact CD1-CB 4.38Å; L179-E182 HydrophobicContact CD1-CG 4.47Å; L179-E182 WeakPolarHBondContact O-CB 3.49Å; L179-E182 PolarHBondContact O-N 2.82Å; R180-E182 PolarHBondContact O-N 2.71Å; E182-P184 VanDerWaalsContact C-N 3.34Å; E182-Y235 WeakPolarHBondContact OE1-CE2 3.42Å; E182-Y235 VanDerWaalsContact OE1-CZ 3.22Å; E182-Y235 PolarHBondContact OE1-OH 3.24Å; E182-T237 HydrophobicContact CG-CG2 4Å; E182-N320 PolarHBondContact OE2-ND2 2.85Å; E182-S333 VanDerWaalsContact CD-CB 3.41Å; E182-S333 WeakPolarHBondContact OE1-CB 3.23Å; E182-S333 PolarHBondContact OE1-OG 3.39Å; E182-S333 PolarHBondContact OE2-OG 3.49Å; E182-S333 VanDerWaalsContact OE2-OG 3.07Å
183R91.7Very high95.7Very high110 Ų11045.3 Ų45.342%0.41520%0.201SC..  trans44.154.1-174.1-65.2-177-71.4171.91112.6R180 Y181 S240 D331R180-R183 PolarHBondContact O-N 2.8Å; R180-R183 VanDerWaalsContact O-N 3.15Å; Y181-R183 VanDerWaalsContact C-N 3.28Å; R183-S240 PolarHBondContact NH2-OG 2.89Å; R183-D331 IonicContact CZ-OD1 3.19Å; R183-D331 IonicContact CZ-OD2 2.66Å; R183-D331 IonicContact NE-OD1 2.78Å; R183-D331 IonicContact NE-OD2 2.72Å; R183-D331 PolarHBondContact NE-OD2 2.62Å; R183-D331 IonicContact NH2-OD1 2.71Å; R183-D331 PolarHBondContact NH2-OD1 3.25Å; R183-D331 IonicContact NH2-OD2 3.7Å; R183-D331 PolarHBondContact NH2-OD2 2.68Å
184P94.3Very high95.5Very high4 Ų446.2 Ų46.23%0.02621%0.205CC..  trans-69.7158.8-175.734.3-39.8000111.3Y112 T113 T114 L179 E182 L203 Q206Y112-P184 HydrophobicContact CD2-CB 3.64Å; Y112-P184 HydrophobicContact CD2-CG 4.41Å; Y112-P184 HydrophobicContact CE2-CB 4.47Å; Y112-P184 HydrophobicContact CG-CB 4.21Å; T113-P184 CarbonylContact O-C 3.57Å; T113-P184 WeakPolarHBondContact O-CA 3.16Å; T114-P184 HydrophobicContact CG2-CB 3.87Å; L179-P184 HydrophobicContact CD1-CB 4.26Å; L179-P184 HydrophobicContact CD1-CG 3.91Å; L179-P184 HydrophobicContact CD2-CG 4.45Å; L179-P184 HydrophobicContact CG-CG 3.89Å; L179-P184 VanDerWaalsContact O-CD 3.3Å; L179-P184 WeakPolarHBondContact O-CD 3.43Å; E182-P184 VanDerWaalsContact C-N 3.34Å; P184-L203 HydrophobicContact CG-CD1 3.64Å; P184-Q206 PolarHBondContact O-NE2 3.49Å
185W95Very high95.4Very high150 Ų15043.7 Ų43.757%0.56819%0.193SC*.EExtended strand (participates in β ladder)trans-92.8111163.1-178.250.3000110.6Y112 T113 Y187 Q206Y112-W185 CarbonylContact C-O 3.54Å; Y112-W185 WeakPolarHBondContact CA-O 3.09Å; T113-W185 HydrophobicContact CG2-CB 4.08Å; T113-W185 HydrophobicContact CG2-CE3 3.7Å; T113-W185 PolarHBondContact N-O 2.9Å; T113-W185 PolarHBondContact O-N 2.85Å; W185-Y187 HydrophobicContact CE3-CD1 4.38Å; W185-Y187 PolarHBondContact O-N 2.87Å; W185-Q206 VanDerWaalsContact CA-NE2 3.32Å
186V96.7Very high95.3Very high13 Ų1348.9 Ų48.98%0.07922%0.217CC..EExtended strand (participates in β ladder)trans-83.9109.4174.2-176.40000108.5L110 H189 L203 V204L110-V186 HydrophobicContact CD1-CG1 4.41Å; L110-V186 HydrophobicContact CD2-CG1 4.01Å; L110-V186 HydrophobicContact CD2-CG2 4.17Å; L110-V186 HydrophobicContact CG-CG1 3.81Å; V186-H189 HydrophobicContact CG1-CB 3.88Å; V186-L203 HydrophobicContact CG2-CD1 4.44Å; V186-L203 HydrophobicContact CG2-CG 4.22Å; V186-V204 HydrophobicContact CG1-CG2 4.29Å
187Y95.6Very high95.2Very high48 Ų4852.4 Ų52.419%0.18824%0.239CC..EExtended strand (participates in β ladder)trans-106-7.4-173.860.7-102.9000113.7M111 Y112 T113 Y122 K145 W185M111-Y187 HydrophobicContact CB-CD2 4.18Å; M111-Y187 HydrophobicContact CB-CE1 4.25Å; M111-Y187 HydrophobicContact CB-CE2 3.41Å; M111-Y187 VanDerWaalsContact CB-CE2 3.41Å; M111-Y187 VanDerWaalsContact CB-CZ 3.46Å; M111-Y187 WeakPolarHBondContact CB-OH 3.44Å; M111-Y187 HydrophobicContact CG-CE2 4.37Å; M111-Y187 PolarHBondContact O-N 3.05Å; M111-Y187 HydrophobicContact SD-CE2 4.1Å; Y112-Y187 WeakPolarHBondContact O-CE1 3.48Å; T113-Y187 HydrophobicContact CG2-CD1 4.21Å; T113-Y187 HydrophobicContact CG2-CE1 4.43Å; Y122-Y187 HydrophobicContact CD1-CE1 4.25Å; K145-Y187 PolarHBondContact NZ-O 2.86Å; W185-Y187 HydrophobicContact CE3-CD1 4.38Å; W185-Y187 PolarHBondContact O-N 2.87Å
188L95.9Very high95.2Very high29 Ų2950.5 Ų50.515%0.15224%0.24CC..EExtended strand (participates in β ladder)trans-145.8127.8168.4-176.4147.9000107.4Y98 R109 L110 M111 K145Y98-L188 WeakPolarHBondContact OH-CD1 3.24Å; R109-L188 HydrophobicContact CB-CD2 4.29Å; L110-L188 CarbonylContact C-O 3.54Å; L110-L188 WeakPolarHBondContact CA-O 3.09Å; M111-L188 HydrophobicContact CB-CB 4.03Å; M111-L188 HydrophobicContact CE-CD1 4.41Å; M111-L188 HydrophobicContact CE-CD2 4.42Å; M111-L188 HydrophobicContact CG-CB 4.18Å; M111-L188 HydrophobicContact CG-CD2 4.09Å; M111-L188 PolarHBondContact N-O 2.88Å; M111-L188 PolarHBondContact O-N 3.4Å; M111-L188 HydrophobicContact SD-CB 4.19Å; M111-L188 HydrophobicContact SD-CD1 4.03Å; M111-L188 HydrophobicContact SD-CD2 4.26Å; M111-L188 HydrophobicContact SD-CG 4.39Å; K145-L188 HydrophobicContact CB-CD1 4.37Å; K145-L188 HydrophobicContact CD-CD1 4.09Å; K145-L188 HydrophobicContact CG-CD1 3.93Å
189H96Very high95.1Very high95 Ų9550.6 Ų50.644%0.4424%0.24SC..EExtended strand (participates in β ladder)trans-145151.3171.465.194.8000111.2R109 V186 V204R109-H189 CarbonylContact O-C 3.6Å; R109-H189 WeakPolarHBondContact O-CA 3.3Å; V186-H189 HydrophobicContact CG1-CB 3.88Å; H189-V204 HydrophobicContact CB-CG2 3.95Å
190Y96.1Very high95.2Very high66 Ų6651.2 Ų51.226%0.25924%0.243SC..EExtended strand (participates in β ladder)trans-142.7120.6161.9-179.4-89.8000107.4R105 S107 R109 P192R105-Y190 WeakPolarHBondContact CA-OH 3.38Å; R105-Y190 HydrophobicContact CB-CE1 4.11Å; R105-Y190 HydrophobicContact CB-CE2 4.22Å; R105-Y190 WeakPolarHBondContact CB-OH 3.38Å; R105-Y190 VanDerWaalsContact CD-CZ 3.46Å; R105-Y190 HydrophobicContact CG-CE2 4.19Å; R105-Y190 WeakPolarHBondContact O-CE1 3.37Å; R105-Y190 PolarHBondContact O-OH 2.98Å; S107-Y190 VanDerWaalsContact O-CD1 3.26Å; S107-Y190 WeakPolarHBondContact O-CD1 3.32Å; R109-Y190 PolarHBondContact N-O 3.33Å; R109-Y190 PolarHBondContact O-N 3.41Å; Y190-P192 HydrophobicContact CD1-CG 4.29Å; Y190-P192 HydrophobicContact CE1-CB 4.49Å; Y190-P192 HydrophobicContact CE1-CG 3.86Å
191L96.5Very high95.3Very high18 Ų1852.8 Ų52.89%0.09425%0.253CS..  trans-114.3104.7-177.4-58-172.7000109L108 F195 Q196 V204L108-L191 HydrophobicContact CD1-CD2 3.34Å; L191-F195 HydrophobicContact CB-CB 4.23Å; L191-F195 HydrophobicContact CD2-CB 4.31Å; L191-Q196 HydrophobicContact CB-CG 4.11Å; L191-Q196 PolarHBondContact O-NE2 3.03Å; L191-V204 HydrophobicContact CD1-CG2 3.95Å; L191-V204 HydrophobicContact CD2-CG2 4.44Å; L191-V204 HydrophobicContact CG-CG2 4.4Å
192P95.4Very high95.4Very high3 Ų353.9 Ų53.92%0.01926%0.258CS..  trans-53.8161.2164.1-21.129.5000111.5D106 S107 Y190 E194 F195 Q196D106-P192 VanDerWaalsContact O-CG 3.3Å; D106-P192 WeakPolarHBondContact O-CG 3.16Å; S107-P192 VanDerWaalsContact C-CG 3.49Å; Y190-P192 HydrophobicContact CD1-CG 4.29Å; Y190-P192 HydrophobicContact CE1-CB 4.49Å; Y190-P192 HydrophobicContact CE1-CG 3.86Å; P192-E194 VanDerWaalsContact CB-CD 3.49Å; P192-E194 WeakPolarHBondContact CB-OE2 3.49Å; P192-E194 PolarHBondContact O-N 3.35Å; P192-E194 VanDerWaalsContact O-N 3.12Å; P192-F195 HydrophobicContact CB-CD2 4.07Å; P192-F195 HydrophobicContact CG-CD2 3.93Å; P192-F195 HydrophobicContact CG-CE2 4.43Å; P192-F195 CarbonylContact O-C 3.47Å; P192-F195 WeakPolarHBondContact O-CA 3.31Å; P192-F195 PolarHBondContact O-N 3.46Å; P192-Q196 PolarHBondContact O-N 2.93Å
193V95.1Very high95.6Very high115 Ų11553.6 Ų53.670%0.69726%0.257SS*.G310 helixtrans-54.8-37.1-171.5120.70000112.7F195 Q196V193-F195 PolarHBondContact O-N 2.79Å; V193-Q196 WeakPolarHBondContact O-CB 3.29Å; V193-Q196 PolarHBondContact O-N 3.22Å; V193-Q196 VanDerWaalsContact O-N 3.12Å
194E94Very high95.8Very high103 Ų10349.4 Ų49.448%0.48124%0.244SC..G310 helixtrans-68.5-21178.766.4-88.5-149.200113.5P192P192-E194 VanDerWaalsContact CB-CD 3.49Å; P192-E194 WeakPolarHBondContact CB-OE2 3.49Å; P192-E194 PolarHBondContact O-N 3.35Å; P192-E194 VanDerWaalsContact O-N 3.12Å
195F96.5Very high95.8Very high19 Ų1954.6 Ų54.68%0.08327%0.272CS..G310 helixtrans-97.6-2.5174-64-81.2000112.5L108 L172 L191 P192 V193 T197 Y200L108-F195 HydrophobicContact CB-CD2 4Å; L108-F195 HydrophobicContact CB-CE1 4.4Å; L108-F195 HydrophobicContact CB-CE2 3.84Å; L108-F195 HydrophobicContact CB-CG 4.36Å; L108-F195 HydrophobicContact CB-CZ 4.06Å; L108-F195 HydrophobicContact CD1-CB 4.27Å; L108-F195 HydrophobicContact CD1-CD1 4.21Å; L108-F195 HydrophobicContact CD1-CD2 4.44Å; L108-F195 HydrophobicContact CD1-CG 4.05Å; L108-F195 HydrophobicContact CD2-CD1 4Å; L108-F195 HydrophobicContact CD2-CE1 3.83Å; L108-F195 HydrophobicContact CD2-CZ 4.22Å; L108-F195 HydrophobicContact CG-CD1 4.48Å; L172-F195 HydrophobicContact CB-CE1 4.44Å; L172-F195 HydrophobicContact CD1-CE1 3.72Å; L172-F195 HydrophobicContact CD1-CZ 3.83Å; L191-F195 HydrophobicContact CB-CB 4.23Å; L191-F195 HydrophobicContact CD2-CB 4.31Å; P192-F195 HydrophobicContact CB-CD2 4.07Å; P192-F195 HydrophobicContact CG-CD2 3.93Å; P192-F195 HydrophobicContact CG-CE2 4.43Å; P192-F195 CarbonylContact O-C 3.47Å; P192-F195 WeakPolarHBondContact O-CA 3.31Å; P192-F195 PolarHBondContact O-N 3.46Å; V193-F195 PolarHBondContact O-N 2.79Å; F195-T197 PolarHBondContact O-N 3.35Å; F195-Y200 HydrophobicContact CB-CD2 4.26Å; F195-Y200 HydrophobicContact CB-CG 4.43Å; F195-Y200 HydrophobicContact CD1-CD1 4.22Å; F195-Y200 AromaticContact CD1-CD2 3.97Å; F195-Y200 HydrophobicContact CD1-CD2 3.97Å; F195-Y200 AromaticContact CD1-CE1 3.86Å; F195-Y200 HydrophobicContact CD1-CE1 3.86Å; F195-Y200 AromaticContact CD1-CE2 3.58Å; F195-Y200 HydrophobicContact CD1-CE2 3.58Å; F195-Y200 HydrophobicContact CD1-CG 4.26Å; F195-Y200 AromaticContact CD1-CZ 3.5Å; F195-Y200 HydrophobicContact CE1-CE1 4.27Å; F195-Y200 HydrophobicContact CE1-CE2 4.24Å; F195-Y200 AromaticContact CE1-CZ 3.83Å; F195-Y200 VanDerWaalsContact O-CB 3.24Å; F195-Y200 WeakPolarHBondContact O-CB 3.39Å
196Q96Very high95.4Very high109 Ų10952.3 Ų52.351%0.50927%0.267SS..SBendtrans-80.955.6172.8-65.1175.521.200110.6L191 P192 V193 I201L191-Q196 HydrophobicContact CB-CG 4.11Å; L191-Q196 PolarHBondContact O-NE2 3.03Å; P192-Q196 PolarHBondContact O-N 2.93Å; V193-Q196 WeakPolarHBondContact O-CB 3.29Å; V193-Q196 PolarHBondContact O-N 3.22Å; V193-Q196 VanDerWaalsContact O-N 3.12Å; Q196-I201 HydrophobicContact CB-CD1 4.24Å; Q196-I201 VanDerWaalsContact O-CD1 3.29Å; Q196-I201 WeakPolarHBondContact O-CD1 3.39Å
197T96.3Very high94.9Very high75 Ų7557.3 Ų57.346%0.4629%0.289SS..SBendtrans-151.9173.5179.5-1670000110.6F195 Y200 I201F195-T197 PolarHBondContact O-N 3.35Å; T197-Y200 HydrophobicContact CG2-CD2 4.43Å; T197-Y200 PolarHBondContact O-N 3.48Å; T197-I201 PolarHBondContact O-N 2.88Å
198S95.6Very high94.1Very high53 Ų5361.2 Ų61.237%0.37131%0.309SS..THydrogen-bonded Turntrans-65.9135.3176.1-161.50000111.7E202S198-E202 VanDerWaalsContact CA-OE2 3.25Å; S198-E202 WeakPolarHBondContact CA-OE2 3.43Å; S198-E202 WeakPolarHBondContact CB-OE1 3.23Å; S198-E202 PolarHBondContact OG-OE1 2.93Å; S198-E202 PolarHBondContact OG-OE2 2.81Å
199P95.6Very high93.2Very high1 Ų160.9 Ų60.91%0.00631%0.308CS..THydrogen-bonded Turncis-99.110.89.440.7-38.9000114.6Q173 A176 R177 E202 L203Q173-P199 HydrophobicContact CG-CG 4.29Å; A176-P199 HydrophobicContact CB-CG 3.78Å; R177-P199 HydrophobicContact CB-CB 4.26Å; R177-P199 HydrophobicContact CB-CG 3.98Å; P199-E202 VanDerWaalsContact C-OE2 3.25Å; P199-E202 WeakPolarHBondContact CA-OE2 3.45Å; P199-L203 WeakPolarHBondContact O-CB 3.25Å; P199-L203 PolarHBondContact O-N 3.11Å; P199-L203 VanDerWaalsContact O-N 3.12Å
200Y97.4Very high92.1Very high14 Ų1467.3 Ų67.36%0.05533%0.328CS..Hα-helixtrans-78.1-39.4-168.5-54.6-77.4000112.8L172 Q173 A176 F195 T197 E202 L203 V204L172-Y200 HydrophobicContact CB-CE1 4.21Å; L172-Y200 VanDerWaalsContact CB-OH 3.25Å; L172-Y200 WeakPolarHBondContact CB-OH 3.18Å; Q173-Y200 VanDerWaalsContact CA-OH 3.28Å; Q173-Y200 WeakPolarHBondContact CA-OH 3.24Å; Q173-Y200 PolarHBondContact N-OH 3.41Å; A176-Y200 HydrophobicContact CB-CD1 3.5Å; A176-Y200 HydrophobicContact CB-CE1 3.47Å; A176-Y200 VanDerWaalsContact CB-CE1 3.47Å; A176-Y200 HydrophobicContact CB-CG 4.48Å; F195-Y200 HydrophobicContact CB-CD2 4.26Å; F195-Y200 HydrophobicContact CB-CG 4.43Å; F195-Y200 HydrophobicContact CD1-CD1 4.22Å; F195-Y200 AromaticContact CD1-CD2 3.97Å; F195-Y200 HydrophobicContact CD1-CD2 3.97Å; F195-Y200 AromaticContact CD1-CE1 3.86Å; F195-Y200 HydrophobicContact CD1-CE1 3.86Å; F195-Y200 AromaticContact CD1-CE2 3.58Å; F195-Y200 HydrophobicContact CD1-CE2 3.58Å; F195-Y200 HydrophobicContact CD1-CG 4.26Å; F195-Y200 AromaticContact CD1-CZ 3.5Å; F195-Y200 HydrophobicContact CE1-CE1 4.27Å; F195-Y200 HydrophobicContact CE1-CE2 4.24Å; F195-Y200 AromaticContact CE1-CZ 3.83Å; F195-Y200 VanDerWaalsContact O-CB 3.24Å; F195-Y200 WeakPolarHBondContact O-CB 3.39Å; T197-Y200 HydrophobicContact CG2-CD2 4.43Å; T197-Y200 PolarHBondContact O-N 3.48Å; Y200-E202 VanDerWaalsContact C-N 3.35Å; Y200-L203 WeakPolarHBondContact O-CB 3.23Å; Y200-L203 PolarHBondContact O-N 3.11Å; Y200-V204 PolarHBondContact O-N 3.36Å
201I96.6Very high90.9Very high64 Ų6470.7 Ų70.733%0.32836%0.356SS..Hα-helixtrans-58.9-50.7175.4-71.3178.3000109.2Q196 T197 L203 V204 D205Q196-I201 HydrophobicContact CB-CD1 4.24Å; Q196-I201 VanDerWaalsContact O-CD1 3.29Å; Q196-I201 WeakPolarHBondContact O-CD1 3.39Å; T197-I201 PolarHBondContact O-N 2.88Å; I201-L203 PolarHBondContact O-N 3.4Å; I201-V204 PolarHBondContact O-N 2.97Å; I201-D205 VanDerWaalsContact CG2-OD2 3.27Å; I201-D205 WeakPolarHBondContact CG2-OD2 3.41Å; I201-D205 WeakPolarHBondContact O-CB 3.25Å; I201-D205 PolarHBondContact O-N 2.91Å
202E95Very high90Very high34 Ų3472.7 Ų72.716%0.15937%0.365CS..Hα-helixtrans-68.6-25.3-178.3-57.194.2140.600112.9S198 P199 Y200 Q206 E207S198-E202 VanDerWaalsContact CA-OE2 3.25Å; S198-E202 WeakPolarHBondContact CA-OE2 3.43Å; S198-E202 WeakPolarHBondContact CB-OE1 3.23Å; S198-E202 PolarHBondContact OG-OE1 2.93Å; S198-E202 PolarHBondContact OG-OE2 2.81Å; P199-E202 VanDerWaalsContact C-OE2 3.25Å; P199-E202 WeakPolarHBondContact CA-OE2 3.45Å; Y200-E202 VanDerWaalsContact C-N 3.35Å; E202-Q206 PolarHBondContact O-N 2.87Å; E202-E207 HydrophobicContact CB-CB 4.01Å; E202-E207 HydrophobicContact CG-CB 4.4Å; E202-E207 WeakPolarHBondContact CG-OE2 3.34Å; E202-E207 PolarHBondContact O-N 3.33Å
203L96.5Very high89.6Confident3 Ų378.9 Ų78.92%0.01640%0.395CS..Hα-helixtrans-68-42.4171173.864.2000111.1L110 A176 L179 R180 P184 V186 P199 Y200 I201L110-L203 HydrophobicContact CD1-CD2 3.64Å; L110-L203 HydrophobicContact CD1-CG 4.36Å; A176-L203 HydrophobicContact CB-CD2 3.99Å; L179-L203 HydrophobicContact CB-CD1 4.49Å; L179-L203 HydrophobicContact CD2-CD1 4.1Å; L179-L203 HydrophobicContact CD2-CD2 3.94Å; L179-L203 HydrophobicContact CG-CD1 3.94Å; R180-L203 HydrophobicContact CG-CB 3.88Å; R180-L203 HydrophobicContact CG-CD1 3.88Å; R180-L203 HydrophobicContact CG-CG 4.46Å; P184-L203 HydrophobicContact CG-CD1 3.64Å; V186-L203 HydrophobicContact CG2-CD1 4.44Å; V186-L203 HydrophobicContact CG2-CG 4.22Å; P199-L203 WeakPolarHBondContact O-CB 3.25Å; P199-L203 PolarHBondContact O-N 3.11Å; P199-L203 VanDerWaalsContact O-N 3.12Å; Y200-L203 WeakPolarHBondContact O-CB 3.23Å; Y200-L203 PolarHBondContact O-N 3.11Å; I201-L203 PolarHBondContact O-N 3.4Å
204V96.5Very high89.5Confident22 Ų2275.3 Ų75.313%0.13337%0.374CS..Hα-helixtrans-72-44.9178.1169.50000111.4V186 H189 L191 Y200 I201 Q206V186-V204 HydrophobicContact CG1-CG2 4.29Å; H189-V204 HydrophobicContact CB-CG2 3.95Å; L191-V204 HydrophobicContact CD1-CG2 3.95Å; L191-V204 HydrophobicContact CD2-CG2 4.44Å; L191-V204 HydrophobicContact CG-CG2 4.4Å; Y200-V204 PolarHBondContact O-N 3.36Å; I201-V204 PolarHBondContact O-N 2.97Å; V204-Q206 PolarHBondContact O-N 3.47Å
205D94.6Very high89.5Confident113 Ų11373 Ų7360%0.60437%0.365SS*.THydrogen-bonded Turntrans-73.9-3-179.9-67.8-15.3000112.8I201 E207I201-D205 VanDerWaalsContact CG2-OD2 3.27Å; I201-D205 WeakPolarHBondContact CG2-OD2 3.41Å; I201-D205 WeakPolarHBondContact O-CB 3.25Å; I201-D205 PolarHBondContact O-N 2.91Å; D205-E207 PolarHBondContact O-N 3.47Å
206Q86.5Confident89.4Confident102 Ų10274.5 Ų74.548%0.47737%0.37SS..THydrogen-bonded Turntrans54.535.8-178.3-50.1-170.2-7600113P184 W185 E202 V204 E208P184-Q206 PolarHBondContact O-NE2 3.49Å; W185-Q206 VanDerWaalsContact CA-NE2 3.32Å; E202-Q206 PolarHBondContact O-N 2.87Å; V204-Q206 PolarHBondContact O-N 3.47Å; Q206-E208 PolarHBondContact O-N 2.99Å
207E86.1Confident89.5Confident117 Ų11771.3 Ų71.355%0.54736%0.358SS..  trans-67.9124.1-178.3-168.7-170.6157.700110.7R180 E202 D205R180-E207 PolarHBondContact NH2-O 2.94Å; E202-E207 HydrophobicContact CB-CB 4.01Å; E202-E207 HydrophobicContact CG-CB 4.4Å; E202-E207 WeakPolarHBondContact CG-OE2 3.34Å; E202-E207 PolarHBondContact O-N 3.33Å; D205-E207 PolarHBondContact O-N 3.47Å
208E77.7Confident89.6Confident130 Ų13068.4 Ų68.461%0.60734%0.339SS*.  trans-64.9133.5-176.3-69.1-161.9149.100113.5Q206 R210Q206-E208 PolarHBondContact O-N 2.99Å; E208-R210 PolarHBondContact O-N 3.43Å
209L77.6Confident89.7Confident23 Ų2369.1 Ų69.112%0.1234%0.342CS..  trans-80.298.5172.3-67.8162.7000110R180 Y181 Q212 R239R180-L209 HydrophobicContact CB-CD1 3.57Å; R180-L209 HydrophobicContact CB-CG 4.46Å; R180-L209 VanDerWaalsContact CZ-CD2 3.47Å; Y181-L209 HydrophobicContact CD2-CD1 4.16Å; Y181-L209 HydrophobicContact CE2-CD1 4.42Å; L209-Q212 HydrophobicContact CB-CG 4.46Å; L209-Q212 HydrophobicContact CD2-CG 4.49Å; L209-Q212 VanDerWaalsContact CD2-NE2 3.33Å; L209-R239 PolarHBondContact O-NH1 3.03Å
210R71.9Confident89.8Confident229 Ų22969.2 Ų69.286%0.86434%0.343SS*.SBendtrans-73.5-31.4-178.1-67.9-174.6177.2177.20.9114.3E208E208-R210 PolarHBondContact O-N 3.43Å
211T71.5Confident89.8Confident137 Ų13772.1 Ų72.184%0.8436%0.362SS*.SBendtrans-133.967.1-167.241.60000112.9
212Q77Confident89.9Confident60 Ų6069.1 Ų69.128%0.2835%0.346SS..  trans-134.4155.1178.1-74.5-174.3-16.400113.2Y181 L209Y181-Q212 HydrophobicContact CE1-CB 4.07Å; Y181-Q212 VanDerWaalsContact CZ-CD 3.41Å; Y181-Q212 VanDerWaalsContact OH-CD 3.24Å; Y181-Q212 PolarHBondContact OH-OE1 3.32Å; L209-Q212 HydrophobicContact CB-CG 4.46Å; L209-Q212 HydrophobicContact CD2-CG 4.49Å; L209-Q212 VanDerWaalsContact CD2-NE2 3.33Å
213M88.8Confident89.9Confident134 Ų13468.9 Ų68.966%0.6635%0.345SS*.  trans-55.4147.6173.5-68.2-65-71.400111.4Y181 I215Y181-M213 WeakPolarHBondContact CE1-O 3.49Å; M213-I215 PolarHBondContact O-N 3.43Å
214P91Very high89.8Confident40 Ų4076.8 Ų76.826%0.2638%0.375SS..SBendtrans-59.9-29177.120.2-31.4000113.7K238 R239 H241 A242P214-K238 WeakPolarHBondContact O-CA 3.27Å; P214-R239 PolarHBondContact O-N 2.93Å; P214-H241 VanDerWaalsContact CA-CE1 3.41Å; P214-H241 WeakPolarHBondContact CA-CE1 3.18Å; P214-H241 VanDerWaalsContact CB-CE1 3.45Å; P214-H241 WeakPolarHBondContact CB-CE1 3.44Å; P214-A242 HydrophobicContact CB-CB 3.49Å; P214-A242 VanDerWaalsContact CB-CB 3.49Å
215I94.9Very high89.6Confident54 Ų5477.4 Ų77.428%0.27738%0.377SS..EExtended strand (participates in β ladder)trans-123.5140.6-175.2-62.2161.3000108.1M213 V217 T237 L244 V250M213-I215 PolarHBondContact O-N 3.43Å; I215-V217 HydrophobicContact CG2-CG2 4.2Å; I215-T237 WeakPolarHBondContact CA-O 3.41Å; I215-L244 HydrophobicContact CD1-CD1 3.77Å; I215-L244 HydrophobicContact CG1-CD1 4.37Å; I215-V250 HydrophobicContact CD1-CB 4.46Å; I215-V250 HydrophobicContact CD1-CG1 4.04Å; I215-V250 HydrophobicContact CD1-CG2 3.7Å; I215-V250 HydrophobicContact CG1-CG1 4.22Å; I215-V250 HydrophobicContact CG1-CG2 4.08Å; I215-V250 HydrophobicContact CG2-CG1 3.66Å
216R95.4Very high88.7Confident50 Ų5078.4 Ų78.419%0.18939%0.387CS..EExtended strand (participates in β ladder)trans-129.9132.5166.3174.3174.9-17684.612.1109.3T178 Y181 I236 T237T178-R216 HydrophobicContact CG2-CG 4.09Å; T178-R216 PolarHBondContact OG1-NE 3.21Å; Y181-R216 HydrophobicContact CD1-CB 3.83Å; Y181-R216 HydrophobicContact CD2-CB 4.34Å; Y181-R216 HydrophobicContact CE1-CB 3.58Å; Y181-R216 HydrophobicContact CE2-CB 4.14Å; Y181-R216 HydrophobicContact CE2-CG 4.3Å; Y181-R216 HydrophobicContact CG-CB 4.2Å; R216-I236 CarbonylContact O-C 3.58Å; R216-I236 WeakPolarHBondContact O-CA 3.35Å; R216-T237 WeakPolarHBondContact CB-OG1 3.43Å; R216-T237 PolarHBondContact N-O 3.29Å; R216-T237 PolarHBondContact O-N 3.26Å
217V97.4Very high87.9Confident42 Ų4281.8 Ų81.826%0.25541%0.408SS..EExtended strand (participates in β ladder)trans-117.8125.6171.6-179.20000106.7I215 I234 Y235 I236 F254I215-V217 HydrophobicContact CG2-CG2 4.2Å; V217-I234 HydrophobicContact CG1-CG2 3.57Å; V217-Y235 CarbonylContact C-O 3.5Å; V217-Y235 WeakPolarHBondContact CA-O 3.29Å; V217-I236 HydrophobicContact CG1-CG1 4.26Å; V217-I236 HydrophobicContact CG2-CG1 4.33Å; V217-I236 HydrophobicContact CG2-CG2 4.42Å; V217-F254 HydrophobicContact CB-CE2 4.16Å; V217-F254 HydrophobicContact CB-CZ 4.3Å; V217-F254 HydrophobicContact CG1-CD1 4.35Å; V217-F254 HydrophobicContact CG1-CD2 4.3Å; V217-F254 HydrophobicContact CG1-CE1 3.68Å; V217-F254 HydrophobicContact CG1-CE2 3.58Å; V217-F254 HydrophobicContact CG1-CZ 3.25Å; V217-F254 HydrophobicContact CG2-CD2 3.99Å; V217-F254 HydrophobicContact CG2-CE2 4.01Å; V217-F254 HydrophobicContact CG2-CG 4.35Å; V217-F254 HydrophobicContact CG2-CZ 4.42Å
218Q97.9Very high87.4Confident15 Ų1577.2 Ų77.27%0.0739%0.393CS..EExtended strand (participates in β ladder)trans-125.6103.2-178.817962.574.300109.5Q174 T178 L220 Y235Q174-Q218 HydrophobicContact CB-CG 4.01Å; T178-Q218 HydrophobicContact CG2-CB 4.1Å; T178-Q218 WeakPolarHBondContact OG1-CB 3.28Å; T178-Q218 WeakPolarHBondContact OG1-CG 3.32Å; Q218-L220 HydrophobicContact CG-CD2 3.87Å; Q218-L220 HydrophobicContact CG-CG 4.14Å; Q218-Y235 PolarHBondContact N-O 3.13Å; Q218-Y235 PolarHBondContact O-N 2.88Å
219P98.1Very high88Confident67 Ų6779.4 Ų79.444%0.43540%0.4SS..EExtended strand (participates in β ladder)trans-64137.2166.2-18.932.5000110V233P219-V233 CarbonylContact C-O 3.59Å
220L98.1Very high88.7Confident4 Ų479.6 Ų79.62%0.02141%0.405CS..EExtended strand (participates in β ladder)trans-135.1166.1178.1-60.5170.4000107.8W134 F167 Q174 I175 Q218 V233W134-L220 HydrophobicContact CZ3-CD1 4.43Å; F167-L220 HydrophobicContact CE1-CB 3.84Å; F167-L220 HydrophobicContact CE1-CD1 4.4Å; F167-L220 HydrophobicContact CZ-CB 4.31Å; F167-L220 HydrophobicContact CZ-CD1 4.14Å; Q174-L220 HydrophobicContact CB-CD2 3.94Å; I175-L220 HydrophobicContact CD1-CD1 4.33Å; I175-L220 HydrophobicContact CG1-CD1 3.71Å; I175-L220 HydrophobicContact CG1-CD2 4.13Å; Q218-L220 HydrophobicContact CG-CD2 3.87Å; Q218-L220 HydrophobicContact CG-CG 4.14Å; L220-V233 WeakPolarHBondContact CA-O 3.33Å; L220-V233 HydrophobicContact CB-CB 4.25Å; L220-V233 WeakPolarHBondContact CB-O 3.46Å; L220-V233 PolarHBondContact N-O 3.41Å; L220-V233 PolarHBondContact O-N 3.16Å
221T97.5Very high89.8Confident74 Ų7469.7 Ų69.745%0.45437%0.37SS..EExtended strand (participates in β ladder)trans-137.4127.2179.3-62.80000108.8F167 A230 V231F167-T221 VanDerWaalsContact CD1-O 3.24Å; F167-T221 WeakPolarHBondContact CD1-O 3.24Å; T221-A230 HydrophobicContact CG2-CB 3.39Å; T221-V231 WeakPolarHBondContact CA-O 3.45Å
222T97.9Very high91Very high1 Ų167.4 Ų67.41%0.00635%0.35CS..  trans-57.6151.6177.165.10000110.6Q39 V165 S166 R224 V231 V233Q39-T222 HydrophobicContact CB-CG2 4.42Å; Q39-T222 PolarHBondContact NE2-OG1 3.45Å; V165-T222 HydrophobicContact CG1-CG2 3.67Å; S166-T222 CarbonylContact O-C 3.59Å; S166-T222 WeakPolarHBondContact O-CA 3.25Å; T222-R224 PolarHBondContact O-N 2.91Å; T222-V231 HydrophobicContact CG2-CB 3.99Å; T222-V231 WeakPolarHBondContact CG2-O 3.3Å; T222-V231 PolarHBondContact N-O 3.23Å; T222-V231 PolarHBondContact OG1-N 2.92Å; T222-V233 HydrophobicContact CG2-CG2 3.87Å
223K96.1Very high92Very high30 Ų3064.6 Ų64.613%0.1334%0.337CS..  trans-52.2135.7169.7-169.8174.7-175.391.30110.3L28 Q39 E130 N131 S166 D168 L225L28-K223 HydrophobicContact CD2-CD 3.73Å; Q39-K223 PolarHBondContact NE2-O 3.12Å; E130-K223 PolarHBondContact O-NZ 3.27Å; N131-K223 VanDerWaalsContact OD1-CD 3.26Å; N131-K223 WeakPolarHBondContact OD1-CD 3.26Å; N131-K223 WeakPolarHBondContact OD1-CE 3.4Å; N131-K223 PolarHBondContact OD1-NZ 3.03Å; S166-K223 PolarHBondContact O-N 3.17Å; D168-K223 IonicContact OD1-NZ 2.74Å; D168-K223 PolarHBondContact OD1-NZ 3.15Å; K223-L225 HydrophobicContact CD-CD2 3.9Å; K223-L225 HydrophobicContact CG-CD2 4.13Å; K223-L225 PolarHBondContact O-N 2.68Å
224R93.8Very high92.5Very high169 Ų16959.2 Ų59.264%0.63831%0.311SS*.  trans-81.4106.8174.7-161179-83-103.56.5108.8T222 G228 A230T222-R224 PolarHBondContact O-N 2.91Å; R224-G228 WeakPolarHBondContact CG-O 3.49Å; R224-A230 HydrophobicContact CB-CB 4.4Å
225L91.3Very high92.8Very high35 Ų3557.3 Ų57.318%0.18330%0.298CS..  trans-98.1165.7177.6-62.3178.6000110.9L28 G37 Q39 K223 N227 G228L28-L225 HydrophobicContact CD1-CD2 4.28Å; G37-L225 VanDerWaalsContact C-CD1 3.49Å; G37-L225 WeakPolarHBondContact O-CD1 3.25Å; Q39-L225 HydrophobicContact CG-CB 4.42Å; Q39-L225 HydrophobicContact CG-CD1 4.16Å; Q39-L225 HydrophobicContact CG-CG 4.3Å; K223-L225 HydrophobicContact CD-CD2 3.9Å; K223-L225 HydrophobicContact CG-CD2 4.13Å; K223-L225 PolarHBondContact O-N 2.68Å; L225-N227 PolarHBondContact O-N 3.1Å; L225-G228 PolarHBondContact O-N 2.88Å
226V77.3Confident93Very high133 Ų13354.8 Ų54.881%0.80629%0.285SS*.THydrogen-bonded Turntrans-50.6125.9-177.6-178.60000110.5G228V226-G228 PolarHBondContact O-N 2.81Å
227N69.3Low93Very high173 Ų17352.4 Ų52.493%0.92528%0.276SS*.THydrogen-bonded Turntrans65.17.4-179.5-53.7-26.1000116.5L225L225-N227 PolarHBondContact O-N 3.1Å
228G76Confident92.8Very high22 Ų2250.4 Ų50.423%0.22726%0.264CS..PPolyproline II helixtrans-103.8136.4177.200000113.1R224 L225 V226R224-G228 WeakPolarHBondContact CG-O 3.49Å; L225-G228 PolarHBondContact O-N 2.88Å; V226-G228 PolarHBondContact O-N 2.81Å
229K88.4Confident92.5Very high175 Ų17550.9 Ų50.976%0.76127%0.265SS*.PPolyproline II helixtrans-75.2136.4161.6-71.3-174.7-179.3-179.40108.2Q39 V231Q39-K229 PolarHBondContact NE2-O 3.28Å; Q39-K229 PolarHBondContact OE1-O 2.69Å; K229-V231 PolarHBondContact O-N 2.87Å
230A92.8Very high92.1Very high28 Ų2849.1 Ų49.123%0.23126%0.255CS..PPolyproline II helixtrans-58.8138171.800000110T221 R224T221-A230 HydrophobicContact CG2-CB 3.39Å; R224-A230 HydrophobicContact CB-CB 4.4Å
231V95.3Very high91.5Very high20 Ų2054 Ų5412%0.12128%0.277CS..PPolyproline II helixtrans-103.6141-179.3-173.90000108.5T221 T222 K229 I337T221-V231 WeakPolarHBondContact CA-O 3.45Å; T222-V231 HydrophobicContact CG2-CB 3.99Å; T222-V231 WeakPolarHBondContact CG2-O 3.3Å; T222-V231 PolarHBondContact N-O 3.23Å; T222-V231 PolarHBondContact OG1-N 2.92Å; K229-V231 PolarHBondContact O-N 2.87Å; V231-I337 HydrophobicContact CG1-CD1 3.8Å; V231-I337 HydrophobicContact CG1-CG1 3.58Å
232E96.4Very high90.9Very high90 Ų9051.8 Ų51.842%0.42127%0.266SS..EExtended strand (participates in β ladder)trans-76.1136.1174.9-174.1169.7-128.500110.4I234E232-I234 HydrophobicContact CG-CG1 4.27Å
233V98.4Very high90.4Very high0 Ų054.6 Ų54.60%029%0.289CS..EExtended strand (participates in β ladder)trans-125.9131.7174.3175.30000107.6V165 F167 P219 L220 T222 V335 C336 I337V165-V233 HydrophobicContact CG1-CG2 4.25Å; F167-V233 HydrophobicContact CZ-CB 4.49Å; F167-V233 HydrophobicContact CZ-CG1 4.44Å; P219-V233 CarbonylContact C-O 3.59Å; L220-V233 WeakPolarHBondContact CA-O 3.33Å; L220-V233 HydrophobicContact CB-CB 4.25Å; L220-V233 WeakPolarHBondContact CB-O 3.46Å; L220-V233 PolarHBondContact N-O 3.41Å; L220-V233 PolarHBondContact O-N 3.16Å; T222-V233 HydrophobicContact CG2-CG2 3.87Å; V233-V335 HydrophobicContact CG1-CG1 3.44Å; V233-V335 VanDerWaalsContact CG1-CG1 3.44Å; V233-C336 CarbonylContact C-O 3.59Å; V233-C336 VanDerWaalsContact CA-O 3.29Å; V233-C336 WeakPolarHBondContact CA-O 2.85Å; V233-I337 HydrophobicContact CG2-CD1 4.44Å; V233-I337 HydrophobicContact CG2-CG1 4.23Å
234I98.3Very high90.2Very high22 Ų2255.7 Ų55.711%0.11330%0.296CS..EExtended strand (participates in β ladder)trans-114.6117.4-178.7-50.7178.9000108.2V217 E232 I236 F254 V335 C336V217-I234 HydrophobicContact CG1-CG2 3.57Å; E232-I234 HydrophobicContact CG-CG1 4.27Å; I234-I236 HydrophobicContact CG2-CD1 4.15Å; I234-I236 HydrophobicContact CG2-CG1 3.8Å; I234-F254 HydrophobicContact CD1-CE1 4.08Å; I234-F254 HydrophobicContact CG2-CE1 3.85Å; I234-F254 HydrophobicContact CG2-CZ 4.38Å; I234-V335 WeakPolarHBondContact O-CA 3.43Å; I234-C336 HydrophobicContact CB-CB 4.41Å; I234-C336 PolarHBondContact N-O 2.96Å; I234-C336 PolarHBondContact O-N 2.75Å
235Y98.6Very high90.1Very high0 Ų048.6 Ų48.60%027%0.271CS..EExtended strand (participates in β ladder)trans-99.6111.6176.7-176.9-167.5000109.9W134 T178 L179 E182 V217 Q218 T237 V335W134-Y235 AromaticContact CH2-CD1 3.56Å; W134-Y235 HydrophobicContact CH2-CD1 3.56Å; W134-Y235 AromaticContact CH2-CD2 3.98Å; W134-Y235 HydrophobicContact CH2-CD2 3.98Å; W134-Y235 AromaticContact CH2-CE1 3.39Å; W134-Y235 HydrophobicContact CH2-CE1 3.39Å; W134-Y235 AromaticContact CH2-CE2 3.82Å; W134-Y235 HydrophobicContact CH2-CE2 3.82Å; W134-Y235 AromaticContact CH2-CG 3.86Å; W134-Y235 HydrophobicContact CH2-CG 3.86Å; W134-Y235 AromaticContact CH2-CZ 3.52Å; W134-Y235 HydrophobicContact CZ2-CE1 4.01Å; W134-Y235 HydrophobicContact CZ2-CE2 4.46Å; W134-Y235 AromaticContact CZ2-CZ 3.95Å; W134-Y235 AromaticContact CZ3-CD1 3.94Å; W134-Y235 HydrophobicContact CZ3-CD1 3.94Å; W134-Y235 HydrophobicContact CZ3-CE1 4.17Å; W134-Y235 HydrophobicContact CZ3-CG 4.21Å; T178-Y235 VanDerWaalsContact CB-CE1 3.48Å; T178-Y235 HydrophobicContact CG2-CD1 3.31Å; T178-Y235 HydrophobicContact CG2-CD2 4.11Å; T178-Y235 HydrophobicContact CG2-CE1 3.43Å; T178-Y235 VanDerWaalsContact CG2-CE1 3.43Å; T178-Y235 HydrophobicContact CG2-CE2 4.21Å; T178-Y235 HydrophobicContact CG2-CG 3.67Å; L179-Y235 VanDerWaalsContact CA-OH 3.27Å; L179-Y235 WeakPolarHBondContact CA-OH 3.36Å; L179-Y235 HydrophobicContact CB-CE1 4.43Å; E182-Y235 WeakPolarHBondContact OE1-CE2 3.42Å; E182-Y235 VanDerWaalsContact OE1-CZ 3.22Å; E182-Y235 PolarHBondContact OE1-OH 3.24Å; V217-Y235 CarbonylContact C-O 3.5Å; V217-Y235 WeakPolarHBondContact CA-O 3.29Å; Q218-Y235 PolarHBondContact N-O 3.13Å; Q218-Y235 PolarHBondContact O-N 2.88Å; Y235-T237 HydrophobicContact CD2-CG2 4.05Å; Y235-T237 HydrophobicContact CE2-CG2 3.53Å; Y235-V335 HydrophobicContact CD2-CG2 3.7Å; Y235-V335 HydrophobicContact CE2-CG2 4.12Å; Y235-V335 HydrophobicContact CG-CG2 4.25Å
236I98.3Very high90.2Very high0 Ų047.1 Ų47.10%026%0.263CS..EExtended strand (participates in β ladder)trans-111128.6-176.1-56.7174.9000108.5R216 V217 I234 L246 V250 I251 F254 S333 A334R216-I236 CarbonylContact O-C 3.58Å; R216-I236 WeakPolarHBondContact O-CA 3.35Å; V217-I236 HydrophobicContact CG1-CG1 4.26Å; V217-I236 HydrophobicContact CG2-CG1 4.33Å; V217-I236 HydrophobicContact CG2-CG2 4.42Å; I234-I236 HydrophobicContact CG2-CD1 4.15Å; I234-I236 HydrophobicContact CG2-CG1 3.8Å; I236-L246 HydrophobicContact CG2-CD1 4.33Å; I236-V250 HydrophobicContact CG2-CG1 3.7Å; I236-I251 HydrophobicContact CD1-CG1 4.08Å; I236-I251 HydrophobicContact CG2-CG1 4.45Å; I236-F254 HydrophobicContact CD1-CD1 3.9Å; I236-F254 HydrophobicContact CD1-CE1 4.39Å; I236-S333 CarbonylContact O-C 3.59Å; I236-S333 WeakPolarHBondContact O-CA 3.33Å; I236-S333 VanDerWaalsContact O-CB 3.24Å; I236-S333 WeakPolarHBondContact O-CB 3.5Å; I236-A334 PolarHBondContact N-O 2.98Å; I236-A334 PolarHBondContact O-N 2.97Å
237T96.1Very high91Very high0 Ų040.9 Ų40.90%023%0.225CC..EExtended strand (participates in β ladder)trans-128.6144.1175.363.60000110.6T178 Y181 E182 I215 R216 Y235 S332T178-T237 HydrophobicContact CG2-CG2 3.61Å; Y181-T237 VanDerWaalsContact CB-OG1 3.3Å; Y181-T237 WeakPolarHBondContact CB-OG1 3.37Å; E182-T237 HydrophobicContact CG-CG2 4Å; I215-T237 WeakPolarHBondContact CA-O 3.41Å; R216-T237 WeakPolarHBondContact CB-OG1 3.43Å; R216-T237 PolarHBondContact N-O 3.29Å; R216-T237 PolarHBondContact O-N 3.26Å; Y235-T237 HydrophobicContact CD2-CG2 4.05Å; Y235-T237 HydrophobicContact CE2-CG2 3.53Å; T237-S332 WeakPolarHBondContact CA-O 3.3Å
238K94Very high92Very high1 Ų133.5 Ų33.50%0.00419%0.186CC..EExtended strand (participates in β ladder)trans-125.3135.2173.5177.4-160.467.281.30109P214 A242 L244 L246 K328 L330 D331 S332P214-K238 WeakPolarHBondContact O-CA 3.27Å; K238-A242 HydrophobicContact CG-CB 4.46Å; K238-L244 HydrophobicContact CD-CB 3.8Å; K238-L244 WeakPolarHBondContact CD-O 3.5Å; K238-L244 WeakPolarHBondContact CE-O 3.14Å; K238-L244 PolarHBondContact NZ-O 3.06Å; K238-L246 HydrophobicContact CB-CD1 3.98Å; K238-L246 HydrophobicContact CD-CB 4.49Å; K238-K328 PolarHBondContact NZ-O 3.05Å; K238-L330 PolarHBondContact NZ-O 3.42Å; K238-D331 WeakPolarHBondContact O-CA 3.27Å; K238-S332 WeakPolarHBondContact CE-OG 3.5Å; K238-S332 PolarHBondContact N-O 3.28Å; K238-S332 PolarHBondContact O-N 3.05Å
239R91.7Very high92.8Very high25 Ų2534.6 Ų34.69%0.09419%0.187CC..  trans-86.7152172.5-63.1-166.366.9-173.62.4112.7Y181 L209 P214 H241 A242 D331Y181-R239 HydrophobicContact CD1-CG 4.06Å; L209-R239 PolarHBondContact O-NH1 3.03Å; P214-R239 PolarHBondContact O-N 2.93Å; R239-H241 VanDerWaalsContact C-N 3.3Å; R239-H241 PolarHBondContact O-N 2.95Å; R239-A242 WeakPolarHBondContact O-CB 3.24Å; R239-A242 PolarHBondContact O-N 2.89Å; R239-D331 WeakPolarHBondContact CA-OD1 3.49Å
240S88.9Confident93.1Very high30 Ų3026.6 Ų26.621%0.2115%0.153CC..G310 helixtrans-56.6-38.3177.654.60000113.8R183 A242 A243 S329 D331R183-S240 PolarHBondContact NH2-OG 2.89Å; S240-A242 PolarHBondContact O-N 2.87Å; S240-A243 PolarHBondContact O-N 2.94Å; S240-A243 VanDerWaalsContact O-N 3.1Å; S240-S329 WeakPolarHBondContact CB-O 3.43Å; S240-D331 PolarHBondContact N-OD1 3.09Å; S240-D331 PolarHBondContact OG-OD1 3.21Å
241H85.5Confident93.3Very high107 Ų10725.2 Ų25.250%0.49514%0.142SC..G310 helixtrans-63.4-16.4-176.87366.3000114P214 R239 A243P214-H241 VanDerWaalsContact CA-CE1 3.41Å; P214-H241 WeakPolarHBondContact CA-CE1 3.18Å; P214-H241 VanDerWaalsContact CB-CE1 3.45Å; P214-H241 WeakPolarHBondContact CB-CE1 3.44Å; R239-H241 VanDerWaalsContact C-N 3.3Å; R239-H241 PolarHBondContact O-N 2.95Å; H241-A243 VanDerWaalsContact C-N 3.35Å
242A84.3Confident93.3Very high26 Ų2624.3 Ų24.322%0.21514%0.136CC..G310 helixtrans-77.7-23.7179.500000112.3P214 K238 R239 S240 L244P214-A242 HydrophobicContact CB-CB 3.49Å; P214-A242 VanDerWaalsContact CB-CB 3.49Å; K238-A242 HydrophobicContact CG-CB 4.46Å; R239-A242 WeakPolarHBondContact O-CB 3.24Å; R239-A242 PolarHBondContact O-N 2.89Å; S240-A242 PolarHBondContact O-N 2.87Å; A242-L244 HydrophobicContact CB-CB 4.42Å; A242-L244 HydrophobicContact CB-CD1 3.95Å; A242-L244 HydrophobicContact CB-CG 3.88Å; A242-L244 PolarHBondContact O-N 3.18Å; A242-L244 VanDerWaalsContact O-N 3.11Å
243A88.2Confident93.2Very high61 Ų6123.1 Ų23.150%0.50414%0.136SC..  trans50.529.5-17300000114.3S240 H241 K328S240-A243 PolarHBondContact O-N 2.94Å; S240-A243 VanDerWaalsContact O-N 3.1Å; H241-A243 VanDerWaalsContact C-N 3.35Å; A243-K328 WeakPolarHBondContact CA-O 3.26Å
244L90.9Very high93Very high53 Ų5327.9 Ų27.928%0.27716%0.157SC..  trans-91.5151.7-179.5-61.1172.6000111.9I215 K238 A242 L246 D249 V250 K328I215-L244 HydrophobicContact CD1-CD1 3.77Å; I215-L244 HydrophobicContact CG1-CD1 4.37Å; K238-L244 HydrophobicContact CD-CB 3.8Å; K238-L244 WeakPolarHBondContact CD-O 3.5Å; K238-L244 WeakPolarHBondContact CE-O 3.14Å; K238-L244 PolarHBondContact NZ-O 3.06Å; A242-L244 HydrophobicContact CB-CB 4.42Å; A242-L244 HydrophobicContact CB-CD1 3.95Å; A242-L244 HydrophobicContact CB-CG 3.88Å; A242-L244 PolarHBondContact O-N 3.18Å; A242-L244 VanDerWaalsContact O-N 3.11Å; L244-L246 PolarHBondContact O-N 3.28Å; L244-D249 HydrophobicContact CB-CB 4.06Å; L244-D249 HydrophobicContact CD2-CB 4.13Å; L244-V250 HydrophobicContact CB-CG2 4.49Å; L244-V250 HydrophobicContact CD1-CG2 4.35Å; L244-K328 WeakPolarHBondContact O-CA 3.27Å
245D91.3Very high92.9Very high19 Ų1927.6 Ų27.610%0.10216%0.156CC..  trans-74.8116.9164.1-173.9-55.7000109.2F247 V248 D249 K328D245-F247 PolarHBondContact O-N 3.23Å; D245-F247 VanDerWaalsContact O-N 3.12Å; D245-F247 WeakPolarHBondContact OD1-CA 3.29Å; D245-F247 WeakPolarHBondContact OD1-CB 3.47Å; D245-F247 WeakPolarHBondContact OD1-CD2 3.42Å; D245-F247 PolarHBondContact OD1-N 2.89Å; D245-V248 HydrophobicContact CB-CB 4.4Å; D245-V248 PolarHBondContact OD1-N 3.1Å; D245-D249 WeakPolarHBondContact CB-OD2 3.37Å; D245-D249 PolarHBondContact N-OD2 2.82Å; D245-D249 VanDerWaalsContact O-CB 3.29Å; D245-D249 WeakPolarHBondContact O-CB 3.49Å; D245-D249 PolarHBondContact O-N 3.28Å; D245-K328 HydrophobicContact CB-CG 4.43Å
246L94.1Very high92.7Very high4 Ų428.8 Ų28.82%0.02117%0.168CC..Iπ-helixtrans-54.5-34.9-179.1175.265.3000112.2I236 K238 L244 V250 I251 S332I236-L246 HydrophobicContact CG2-CD1 4.33Å; K238-L246 HydrophobicContact CB-CD1 3.98Å; K238-L246 HydrophobicContact CD-CB 4.49Å; L244-L246 PolarHBondContact O-N 3.28Å; L246-V250 HydrophobicContact CD1-CB 4.46Å; L246-V250 VanDerWaalsContact O-CB 3.3Å; L246-V250 WeakPolarHBondContact O-CB 3.25Å; L246-I251 HydrophobicContact CD1-CD1 4.27Å; L246-I251 HydrophobicContact CD1-CG1 4.35Å; L246-I251 HydrophobicContact CD2-CD1 4.21Å; L246-I251 HydrophobicContact CG-CD1 3.82Å; L246-I251 HydrophobicContact CG-CG1 4.33Å; L246-I251 WeakPolarHBondContact O-CG1 3.2Å; L246-I251 PolarHBondContact O-N 2.9Å; L246-S332 WeakPolarHBondContact CB-OG 3.04Å
247F93.8Very high92.6Very high3 Ų329 Ų291%0.01317%0.17CC..Iπ-helixtrans-86.8-53.4-169.7-47.5-83.3000110.7D245 I251 A252 T263 V278 L306 T319 S321 D322 R323D245-F247 PolarHBondContact O-N 3.23Å; D245-F247 VanDerWaalsContact O-N 3.12Å; D245-F247 WeakPolarHBondContact OD1-CA 3.29Å; D245-F247 WeakPolarHBondContact OD1-CB 3.47Å; D245-F247 WeakPolarHBondContact OD1-CD2 3.42Å; D245-F247 PolarHBondContact OD1-N 2.89Å; F247-I251 HydrophobicContact CD1-CD1 4.11Å; F247-I251 PolarHBondContact O-N 2.78Å; F247-A252 WeakPolarHBondContact O-CB 3.5Å; F247-A252 PolarHBondContact O-N 2.87Å; F247-T263 HydrophobicContact CZ-CG2 4.46Å; F247-V278 HydrophobicContact CB-CB 4.41Å; F247-V278 HydrophobicContact CB-CG1 4.05Å; F247-V278 HydrophobicContact CB-CG2 4.08Å; F247-L306 HydrophobicContact CB-CD2 4.32Å; F247-L306 HydrophobicContact CD1-CD1 3.7Å; F247-L306 HydrophobicContact CD1-CD2 3.49Å; F247-L306 VanDerWaalsContact CD1-CD2 3.49Å; F247-L306 HydrophobicContact CD1-CG 4.01Å; F247-L306 HydrophobicContact CE1-CD1 3.77Å; F247-L306 HydrophobicContact CE1-CD2 4.21Å; F247-L306 HydrophobicContact CE1-CG 4.27Å; F247-L306 HydrophobicContact CG-CD2 4.3Å; F247-T319 HydrophobicContact CE1-CG2 3.9Å; F247-T319 HydrophobicContact CZ-CG2 4.37Å; F247-S321 WeakPolarHBondContact CZ-O 3.43Å; F247-D322 WeakPolarHBondContact CE2-O 3.33Å; F247-R323 HydrophobicContact CD1-CG 4.5Å; F247-R323 HydrophobicContact CD2-CG 3.35Å; F247-R323 HydrophobicContact CE1-CG 4.42Å; F247-R323 HydrophobicContact CE2-CB 4.3Å; F247-R323 HydrophobicContact CE2-CG 3.3Å; F247-R323 HydrophobicContact CG-CG 3.95Å; F247-R323 HydrophobicContact CZ-CG 3.85Å
248V91.5Very high92.5Very high17 Ų1730.7 Ų30.710%0.10318%0.18CC..Iπ-helixtrans-83.4-34.1-173.2-178.60000112.6D245 P253 R274 V278D245-V248 HydrophobicContact CB-CB 4.4Å; D245-V248 PolarHBondContact OD1-N 3.1Å; V248-P253 WeakPolarHBondContact O-CD 3.39Å; V248-P253 VanDerWaalsContact O-CG 3.22Å; V248-P253 WeakPolarHBondContact O-CG 3.18Å; V248-R274 HydrophobicContact CG1-CG 3.95Å; V248-V278 HydrophobicContact CG2-CB 3.88Å; V248-V278 HydrophobicContact CG2-CG2 3.86Å
249D92.1Very high92.6Very high46 Ų4630.7 Ų30.725%0.24618%0.18CC..Iπ-helixtrans-93.5-19.3-178.3-59.8-45.4000113L244 D245 R274L244-D249 HydrophobicContact CB-CB 4.06Å; L244-D249 HydrophobicContact CD2-CB 4.13Å; D245-D249 WeakPolarHBondContact CB-OD2 3.37Å; D245-D249 PolarHBondContact N-OD2 2.82Å; D245-D249 VanDerWaalsContact O-CB 3.29Å; D245-D249 WeakPolarHBondContact O-CB 3.49Å; D245-D249 PolarHBondContact O-N 3.28Å; D249-R274 IonicContact OD1-CZ 2.89Å; D249-R274 IonicContact OD1-NH1 3.52Å; D249-R274 PolarHBondContact OD1-NH1 2.98Å; D249-R274 IonicContact OD1-NH2 3.03Å; D249-R274 PolarHBondContact OD1-NH2 2.85Å
250V94.9Very high92.8Very high6 Ų629.9 Ų29.94%0.03618%0.178CC..Iπ-helixtrans-119.7-65.6-174.3-1680000112.7I215 I236 L244 L246 F254I215-V250 HydrophobicContact CD1-CB 4.46Å; I215-V250 HydrophobicContact CD1-CG1 4.04Å; I215-V250 HydrophobicContact CD1-CG2 3.7Å; I215-V250 HydrophobicContact CG1-CG1 4.22Å; I215-V250 HydrophobicContact CG1-CG2 4.08Å; I215-V250 HydrophobicContact CG2-CG1 3.66Å; I236-V250 HydrophobicContact CG2-CG1 3.7Å; L244-V250 HydrophobicContact CB-CG2 4.49Å; L244-V250 HydrophobicContact CD1-CG2 4.35Å; L246-V250 HydrophobicContact CD1-CB 4.46Å; L246-V250 VanDerWaalsContact O-CB 3.3Å; L246-V250 WeakPolarHBondContact O-CB 3.25Å; V250-F254 WeakPolarHBondContact O-CB 3.48Å; V250-F254 PolarHBondContact O-N 2.81Å
251I96.5Very high93.1Very high0 Ų028.4 Ų28.40%017%0.168CC..Iπ-helixtrans-65.7-53-171.6-66.1167.7000112I236 L246 F247 F254 T255 Y259 L306 A334I236-I251 HydrophobicContact CD1-CG1 4.08Å; I236-I251 HydrophobicContact CG2-CG1 4.45Å; L246-I251 HydrophobicContact CD1-CD1 4.27Å; L246-I251 HydrophobicContact CD1-CG1 4.35Å; L246-I251 HydrophobicContact CD2-CD1 4.21Å; L246-I251 HydrophobicContact CG-CD1 3.82Å; L246-I251 HydrophobicContact CG-CG1 4.33Å; L246-I251 WeakPolarHBondContact O-CG1 3.2Å; L246-I251 PolarHBondContact O-N 2.9Å; F247-I251 HydrophobicContact CD1-CD1 4.11Å; F247-I251 PolarHBondContact O-N 2.78Å; I251-F254 PolarHBondContact O-N 2.96Å; I251-T255 WeakPolarHBondContact O-CB 3.35Å; I251-T255 PolarHBondContact O-N 3.45Å; I251-T255 PolarHBondContact O-OG1 2.96Å; I251-Y259 HydrophobicContact CG2-CE2 3.98Å; I251-L306 HydrophobicContact CD1-CD1 4.06Å; I251-A334 HydrophobicContact CD1-CB 3.5Å; I251-A334 VanDerWaalsContact CD1-CB 3.5Å; I251-A334 HydrophobicContact CG1-CB 4.37Å
252A95.2Very high93.6Very high0 Ų023.3 Ų23.30%014%0.144CC..Hα-helixtrans-64.1-45.5-175.300000112.7F247 G256 T257 Y259 V278F247-A252 WeakPolarHBondContact O-CB 3.5Å; F247-A252 PolarHBondContact O-N 2.87Å; A252-G256 WeakPolarHBondContact O-CA 3.09Å; A252-G256 PolarHBondContact O-N 2.75Å; A252-T257 WeakPolarHBondContact CB-O 3.18Å; A252-T257 PolarHBondContact O-N 3.49Å; A252-Y259 HydrophobicContact CB-CD2 4.12Å; A252-Y259 HydrophobicContact CB-CE2 4.39Å; A252-V278 HydrophobicContact CB-CG2 3.87Å
253P94Very high94.1Very high65 Ų6522.3 Ų22.342%0.42214%0.135SC..Hα-helixtrans-65.3-40.1174.1-23.535.7000113.7V248 G256V248-P253 WeakPolarHBondContact O-CD 3.39Å; V248-P253 VanDerWaalsContact O-CG 3.22Å; V248-P253 WeakPolarHBondContact O-CG 3.18Å; P253-G256 PolarHBondContact O-N 3.02Å
254F95.3Very high94.2Very high100 Ų10023.3 Ų23.344%0.43913%0.128SC..Hα-helixtrans-64.2-43.5179.8172.6-98.1000112V217 I234 I236 V250 I251V217-F254 HydrophobicContact CB-CE2 4.16Å; V217-F254 HydrophobicContact CB-CZ 4.3Å; V217-F254 HydrophobicContact CG1-CD1 4.35Å; V217-F254 HydrophobicContact CG1-CD2 4.3Å; V217-F254 HydrophobicContact CG1-CE1 3.68Å; V217-F254 HydrophobicContact CG1-CE2 3.58Å; V217-F254 HydrophobicContact CG1-CZ 3.25Å; V217-F254 HydrophobicContact CG2-CD2 3.99Å; V217-F254 HydrophobicContact CG2-CE2 4.01Å; V217-F254 HydrophobicContact CG2-CG 4.35Å; V217-F254 HydrophobicContact CG2-CZ 4.42Å; I234-F254 HydrophobicContact CD1-CE1 4.08Å; I234-F254 HydrophobicContact CG2-CE1 3.85Å; I234-F254 HydrophobicContact CG2-CZ 4.38Å; I236-F254 HydrophobicContact CD1-CD1 3.9Å; I236-F254 HydrophobicContact CD1-CE1 4.39Å; V250-F254 WeakPolarHBondContact O-CB 3.48Å; V250-F254 PolarHBondContact O-N 2.81Å; I251-F254 PolarHBondContact O-N 2.96Å
255T95.4Very high93.9Very high16 Ų1622.6 Ų22.610%0.09813%0.13CC..Hα-helixtrans-85.7-14.5-178.556.80000113.6I251 Y259 I315I251-T255 WeakPolarHBondContact O-CB 3.35Å; I251-T255 PolarHBondContact O-N 3.45Å; I251-T255 PolarHBondContact O-OG1 2.96Å; T255-Y259 VanDerWaalsContact CB-OH 3.3Å; T255-Y259 WeakPolarHBondContact CB-OH 3.34Å; T255-Y259 WeakPolarHBondContact CG2-OH 3.28Å; T255-Y259 VanDerWaalsContact OG1-CE2 3.24Å; T255-Y259 WeakPolarHBondContact OG1-CE2 3.47Å; T255-Y259 PolarHBondContact OG1-OH 3.23Å; T255-I315 HydrophobicContact CG2-CD1 4.03Å
256G94.9Very high93.2Very high25 Ų2526.2 Ų26.226%0.25815%0.147SC..THydrogen-bonded Turntrans6638.6178.800000113.3A252 P253 Y276A252-G256 WeakPolarHBondContact O-CA 3.09Å; A252-G256 PolarHBondContact O-N 2.75Å; P253-G256 PolarHBondContact O-N 3.02Å; G256-Y276 VanDerWaalsContact C-CD1 3.48Å; G256-Y276 WeakPolarHBondContact O-CE1 3.2Å
257T95.6Very high91.8Very high5 Ų536 Ų363%0.03118%0.183CC..SBendtrans-149.8157.1177.3-172.30000112.6A252 Y259 N310 R313A252-T257 WeakPolarHBondContact CB-O 3.18Å; A252-T257 PolarHBondContact O-N 3.49Å; T257-Y259 HydrophobicContact CG2-CD2 4.2Å; T257-Y259 HydrophobicContact CG2-CE1 4.42Å; T257-Y259 HydrophobicContact CG2-CE2 3.4Å; T257-Y259 VanDerWaalsContact CG2-CE2 3.4Å; T257-Y259 WeakPolarHBondContact CG2-OH 3.39Å; T257-Y259 WeakPolarHBondContact O-CD2 3.4Å; T257-Y259 WeakPolarHBondContact O-CE2 3.26Å; T257-N310 VanDerWaalsContact OG1-CB 3.26Å; T257-N310 WeakPolarHBondContact OG1-CB 3.3Å; T257-R313 HydrophobicContact CG2-CB 4.45Å
258T94.8Very high90.3Very high36 Ų3643 Ų4322%0.22122%0.221CC..  trans-78.7148.9171.6-670000110.9A277 S308 T309T258-A277 CarbonylContact C-O 3.56Å; T258-A277 VanDerWaalsContact CA-O 3.23Å; T258-A277 WeakPolarHBondContact CA-O 3.3Å; T258-A277 HydrophobicContact CG2-CB 4.06Å; T258-A277 WeakPolarHBondContact CG2-O 3.45Å; T258-A277 PolarHBondContact OG1-N 3.43Å; T258-S308 WeakPolarHBondContact O-CA 3.43Å; T258-T309 WeakPolarHBondContact CB-OG1 3.43Å; T258-T309 HydrophobicContact CG2-CG2 4.08Å; T258-T309 WeakPolarHBondContact CG2-OG1 3.49Å; T258-T309 PolarHBondContact O-N 3.48Å; T258-T309 PolarHBondContact O-OG1 3.43Å
259Y95.6Very high88.8Confident0 Ų044.1 Ų44.10%023%0.228CC..EExtended strand (participates in β ladder)trans-128.9151.3-179.8-70.7-95.3000113.1I251 A252 T255 T257 A277 V278 R279 L306 L307 I315I251-Y259 HydrophobicContact CG2-CE2 3.98Å; A252-Y259 HydrophobicContact CB-CD2 4.12Å; A252-Y259 HydrophobicContact CB-CE2 4.39Å; T255-Y259 VanDerWaalsContact CB-OH 3.3Å; T255-Y259 WeakPolarHBondContact CB-OH 3.34Å; T255-Y259 WeakPolarHBondContact CG2-OH 3.28Å; T255-Y259 VanDerWaalsContact OG1-CE2 3.24Å; T255-Y259 WeakPolarHBondContact OG1-CE2 3.47Å; T255-Y259 PolarHBondContact OG1-OH 3.23Å; T257-Y259 HydrophobicContact CG2-CD2 4.2Å; T257-Y259 HydrophobicContact CG2-CE1 4.42Å; T257-Y259 HydrophobicContact CG2-CE2 3.4Å; T257-Y259 VanDerWaalsContact CG2-CE2 3.4Å; T257-Y259 WeakPolarHBondContact CG2-OH 3.39Å; T257-Y259 WeakPolarHBondContact O-CD2 3.4Å; T257-Y259 WeakPolarHBondContact O-CE2 3.26Å; Y259-A277 PolarHBondContact N-O 2.83Å; Y259-V278 CarbonylContact O-C 3.58Å; Y259-V278 VanDerWaalsContact O-CA 3.3Å; Y259-V278 WeakPolarHBondContact O-CA 3.08Å; Y259-R279 PolarHBondContact O-N 3.04Å; Y259-L306 HydrophobicContact CD1-CB 3.73Å; Y259-L306 HydrophobicContact CD1-CD2 4.43Å; Y259-L306 HydrophobicContact CE1-CB 4.43Å; Y259-L306 HydrophobicContact CG-CB 4.36Å; Y259-L306 HydrophobicContact CG-CD2 4.27Å; Y259-L307 CarbonylContact C-O 3.59Å; Y259-L307 VanDerWaalsContact CA-O 3.27Å; Y259-L307 WeakPolarHBondContact CA-O 3.3Å; Y259-L307 VanDerWaalsContact CD1-C 3.43Å; Y259-I315 HydrophobicContact CE1-CB 4.31Å; Y259-I315 HydrophobicContact CE1-CG2 4.15Å; Y259-I315 WeakPolarHBondContact OH-CG2 3.33Å
260D95.3Very high87.3Confident8 Ų848.2 Ų48.24%0.04325%0.25CC..EExtended strand (participates in β ladder)trans-100136.2158.1-66.2-17.2000108.3R279 I281 L306 L307 T309D260-R279 CarbonylContact C-O 3.51Å; D260-R279 WeakPolarHBondContact CA-O 3.39Å; D260-R279 WeakPolarHBondContact OD1-CB 3.24Å; D260-R279 IonicContact OD1-CZ 3.23Å; D260-R279 IonicContact OD1-NE 3.32Å; D260-R279 PolarHBondContact OD1-NE 2.79Å; D260-R279 IonicContact OD1-NH2 3.78Å; D260-R279 PolarHBondContact OD1-NH2 3.41Å; D260-R279 IonicContact OD2-CZ 2.87Å; D260-R279 IonicContact OD2-NH2 2.74Å; D260-R279 PolarHBondContact OD2-NH2 2.71Å; D260-I281 HydrophobicContact CB-CD1 3.92Å; D260-I281 HydrophobicContact CB-CG1 3.9Å; D260-L306 CarbonylContact O-C 3.58Å; D260-L306 WeakPolarHBondContact O-CA 3.18Å; D260-L307 PolarHBondContact N-O 2.94Å; D260-L307 PolarHBondContact O-N 2.94Å; D260-T309 HydrophobicContact CB-CG2 4.49Å; D260-T309 WeakPolarHBondContact OD1-CG2 3.27Å
261S95.6Very high85.9Confident0 Ų049 Ų490%026%0.255CS..EExtended strand (participates in β ladder)trans-119.7125.6-175.665.70000111.2R279 N280 I281 R323S261-R279 PolarHBondContact N-O 3.05Å; S261-R279 PolarHBondContact OG-O 3.39Å; S261-N280 PolarHBondContact OG-OD1 2.8Å; S261-I281 PolarHBondContact O-N 2.78Å; S261-R323 WeakPolarHBondContact OG-CD 3.04Å; S261-R323 PolarHBondContact OG-NH1 2.8Å
262W96.6Very high84.2Confident0 Ų053.4 Ų53.40%029%0.286CS..EExtended strand (participates in β ladder)trans-99.986.6168.7-176-115.2000108.7Y44 I281 L285 L296 R298 D301 S303 R304 W305Y44-W262 PolarHBondContact OH-NE1 3.24Å; W262-I281 HydrophobicContact CB-CD1 4.21Å; W262-I281 HydrophobicContact CE3-CB 3.83Å; W262-I281 HydrophobicContact CE3-CG2 3.58Å; W262-I281 HydrophobicContact CZ3-CB 4.44Å; W262-I281 HydrophobicContact CZ3-CG2 3.81Å; W262-L285 HydrophobicContact CB-CD1 4.31Å; W262-L285 HydrophobicContact CD2-CD1 3.22Å; W262-L285 HydrophobicContact CD2-CG 4.43Å; W262-L285 HydrophobicContact CE3-CD1 3.35Å; W262-L285 HydrophobicContact CE3-CG 4.16Å; W262-L285 HydrophobicContact CG-CD1 3.72Å; W262-L285 HydrophobicContact CH2-CD1 3.98Å; W262-L285 HydrophobicContact CH2-CG 4.44Å; W262-L285 HydrophobicContact CZ2-CD1 3.91Å; W262-L285 HydrophobicContact CZ3-CD1 3.72Å; W262-L285 HydrophobicContact CZ3-CG 4.16Å; W262-L296 HydrophobicContact CZ2-CB 4.35Å; W262-R298 VanDerWaalsContact C-NH1 3.34Å; W262-R298 HydrophobicContact CH2-CB 3.75Å; W262-R298 HydrophobicContact CZ2-CB 4.21Å; W262-R298 HydrophobicContact CZ3-CB 4.25Å; W262-R298 VanDerWaalsContact NE1-CZ 3.33Å; W262-R298 PolarHBondContact O-NH1 3.04Å; W262-D301 HydrophobicContact CZ2-CB 4.42Å; W262-D301 PolarHBondContact NE1-OD2 3.41Å; W262-S303 PolarHBondContact NE1-OG 2.75Å; W262-R304 VanDerWaalsContact O-CA 3.3Å; W262-R304 WeakPolarHBondContact O-CA 3.45Å; W262-W305 HydrophobicContact CB-CD2 3.76Å; W262-W305 HydrophobicContact CB-CE3 4.19Å; W262-W305 HydrophobicContact CB-CG 4.29Å; W262-W305 HydrophobicContact CB-CH2 3.92Å; W262-W305 HydrophobicContact CB-CZ2 3.48Å; W262-W305 VanDerWaalsContact CB-CZ2 3.48Å; W262-W305 HydrophobicContact CB-CZ3 4.24Å; W262-W305 AromaticContact CD1-CD1 3.79Å; W262-W305 AromaticContact CD1-CE2 3.73Å; W262-W305 AromaticContact CD1-NE1 3.17Å; W262-W305 AromaticContact CG-CE2 3.76Å; W262-W305 AromaticContact CG-CZ2 3.84Å; W262-W305 HydrophobicContact CG-CZ2 3.84Å; W262-W305 AromaticContact CG-NE1 3.68Å; W262-W305 PolarHBondContact N-O 2.71Å; W262-W305 PolarHBondContact O-N 3.29Å; W262-W305 VanDerWaalsContact O-N 3.16Å
263T93.8Very high82.9Confident5 Ų560.3 Ų60.33%0.03132%0.323CS..SBendtrans-140.3172.3176.168.70000109.4F247 R304 T319 R323F247-T263 HydrophobicContact CZ-CG2 4.46Å; T263-R304 HydrophobicContact CG2-CB 4.05Å; T263-R304 HydrophobicContact CG2-CG 4.46Å; T263-T319 HydrophobicContact CG2-CG2 4.19Å; T263-R323 WeakPolarHBondContact OG1-CG 3.1Å; T263-R323 PolarHBondContact OG1-N 3.11Å
264K91.1Very high82.2Confident81 Ų8163.3 Ų63.335%0.35233%0.325SS..  trans-65.9137.5159.9-59.8173.8-174.5169.80107.5D302 D322 R323K264-D302 IonicContact NZ-OD1 2.7Å; K264-D322 HydrophobicContact CB-CB 4.06Å; K264-D322 WeakPolarHBondContact CB-OD1 3.11Å; K264-D322 PolarHBondContact N-OD1 2.78Å; K264-R323 PolarHBondContact O-N 3.29Å
265A84.7Confident81.8Confident39 Ų3962.8 Ų62.832%0.32234%0.34SS..BIsolated β-bridgetrans-143.7148.9-179.600000110.8N280 R323A265-N280 HydrophobicContact CB-CB 4.37Å; A265-N280 VanDerWaalsContact CB-CG 3.47Å; A265-N280 WeakPolarHBondContact CB-ND2 3.46Å; A265-N280 WeakPolarHBondContact CB-OD1 3.34Å; A265-R323 VanDerWaalsContact CA-O 3.29Å; A265-R323 WeakPolarHBondContact CA-O 3.27Å; A265-R323 HydrophobicContact CB-CB 4Å
266E75.7Confident81.7Confident95 Ų9566.3 Ų66.344%0.44435%0.352SS..  trans-76.4148.1165-68.5173.8-143.100109.5R323 T324 E325E266-R323 PolarHBondContact N-O 3.26Å; E266-T324 HydrophobicContact CG-CG2 4.45Å; E266-E325 PolarHBondContact OE1-N 2.97Å
267R64.7Low81.5Confident209 Ų20966 Ų6679%0.78935%0.347SS*.SBendtrans-69.8152175.5-71-169.8-70.9-1100.9110.1
268N62.3Low81.4Confident150 Ų15065.9 Ų65.980%0.80235%0.347SS*.  trans71.745.7175.8-48.1-28.6000114.8N270N268-N270 PolarHBondContact O-N 2.97Å
269V60.4Low81.2Confident41 Ų4168 Ų6825%0.24835%0.35CS..  trans-71.4116.9172.1-172.80000108.9C271V269-C271 PolarHBondContact O-N 3.38Å; V269-C271 VanDerWaalsContact O-N 3.15Å; V269-C271 PolarHBondContact O-SG 2.9Å; V269-C271 VanDerWaalsContact O-SG 3.41Å
270N60.3Low81.1Confident132 Ų13268.2 Ų68.271%0.70635%0.352SS*.  trans-63.7112.7-176-143.918.9000110.5N268N268-N270 PolarHBondContact O-N 2.97Å
271C66.6Low81.1Confident21 Ų2168 Ų6814%0.14235%0.351CS..  trans-101-17.7-177.4-62.30000115.1V269 D273 C358V269-C271 PolarHBondContact O-N 3.38Å; V269-C271 VanDerWaalsContact O-N 3.15Å; V269-C271 PolarHBondContact O-SG 2.9Å; V269-C271 VanDerWaalsContact O-SG 3.41Å; C271-D273 VanDerWaalsContact C-N 3.32Å; C271-D273 PolarHBondContact O-N 2.89Å; C271-C358 HydrophobicContact CB-CB 3.12Å; C271-C358 WeakPolarHBondContact CB-SG 3.22Å; C271-C358 VanDerWaalsContact SG-CA 3.52Å; C271-C358 WeakPolarHBondContact SG-CB 3.21Å; C271-C358 CovalentContact SG-SG 2.02Å; C271-C358 PolarHBondContact SG-SG 2.78Å
272S59.8Low80.9Confident93 Ų9372.2 Ų72.265%0.6537%0.371SS*.THydrogen-bonded Turntrans-71.9-19.1-153.3-49.50000115.5
273D69.2Low80.9Confident145 Ų14574.3 Ų74.378%0.77539%0.386SS*.THydrogen-bonded Turntrans-113.622.4-169.3-61.2-37.6000114.6C271C271-D273 VanDerWaalsContact C-N 3.32Å; C271-D273 PolarHBondContact O-N 2.89Å
274R79.3Confident81Confident128 Ų12874.8 Ų74.848%0.48339%0.392SS..  trans-119.9141-176.3-60.5-67.4-172.1128.23.9112.2V248 D249 Y276V248-R274 HydrophobicContact CG1-CG 3.95Å; D249-R274 IonicContact OD1-CZ 2.89Å; D249-R274 IonicContact OD1-NH1 3.52Å; D249-R274 PolarHBondContact OD1-NH1 2.98Å; D249-R274 IonicContact OD1-NH2 3.03Å; D249-R274 PolarHBondContact OD1-NH2 2.85Å; R274-Y276 PolarHBondContact O-N 2.92Å
275A86.9Confident81.2Confident90 Ų9070.9 Ų70.974%0.74438%0.375SS*.SBendtrans-61.9-29.8174.600000112.9
276Y91.7Very high81.8Confident89 Ų8969.6 Ų69.635%0.34936%0.362SS..SBendtrans-132.6122.7177.3-52.5-68.4000108.9G256 R274G256-Y276 VanDerWaalsContact C-CD1 3.48Å; G256-Y276 WeakPolarHBondContact O-CE1 3.2Å; R274-Y276 PolarHBondContact O-N 2.92Å
277A91.5Very high82.7Confident19 Ų1965 Ų6516%0.15734%0.341CS..  trans-92.6159.6-177.700000111.5T258 Y259T258-A277 CarbonylContact C-O 3.56Å; T258-A277 VanDerWaalsContact CA-O 3.23Å; T258-A277 WeakPolarHBondContact CA-O 3.3Å; T258-A277 HydrophobicContact CG2-CB 4.06Å; T258-A277 WeakPolarHBondContact CG2-O 3.45Å; T258-A277 PolarHBondContact OG1-N 3.43Å; Y259-A277 PolarHBondContact N-O 2.83Å
278V92.7Very high84.1Confident3 Ų357.8 Ų57.82%0.01832%0.32CS..EExtended strand (participates in β ladder)trans-128.1113165.8-174.20000107.8F247 V248 A252 Y259 L306 R323F247-V278 HydrophobicContact CB-CB 4.41Å; F247-V278 HydrophobicContact CB-CG1 4.05Å; F247-V278 HydrophobicContact CB-CG2 4.08Å; V248-V278 HydrophobicContact CG2-CB 3.88Å; V248-V278 HydrophobicContact CG2-CG2 3.86Å; A252-V278 HydrophobicContact CB-CG2 3.87Å; Y259-V278 CarbonylContact O-C 3.58Å; Y259-V278 VanDerWaalsContact O-CA 3.3Å; Y259-V278 WeakPolarHBondContact O-CA 3.08Å; V278-L306 HydrophobicContact CG1-CD2 3.94Å; V278-R323 VanDerWaalsContact O-CZ 3.26Å; V278-R323 PolarHBondContact O-NH1 2.84Å; V278-R323 PolarHBondContact O-NH2 3.13Å
279R92.5Very high85.5Confident80 Ų8054.1 Ų54.130%0.30230%0.298SS..EExtended strand (participates in β ladder)trans-97.1147.7-177.2-65.3179.4-58.4175.612.8111.2Y259 D260 S261 T309 V355 C358Y259-R279 PolarHBondContact O-N 3.04Å; D260-R279 CarbonylContact C-O 3.51Å; D260-R279 WeakPolarHBondContact CA-O 3.39Å; D260-R279 WeakPolarHBondContact OD1-CB 3.24Å; D260-R279 IonicContact OD1-CZ 3.23Å; D260-R279 IonicContact OD1-NE 3.32Å; D260-R279 PolarHBondContact OD1-NE 2.79Å; D260-R279 IonicContact OD1-NH2 3.78Å; D260-R279 PolarHBondContact OD1-NH2 3.41Å; D260-R279 IonicContact OD2-CZ 2.87Å; D260-R279 IonicContact OD2-NH2 2.74Å; D260-R279 PolarHBondContact OD2-NH2 2.71Å; S261-R279 PolarHBondContact N-O 3.05Å; S261-R279 PolarHBondContact OG-O 3.39Å; R279-T309 VanDerWaalsContact NH2-CG2 3.28Å; R279-V355 HydrophobicContact CB-CG1 3.42Å; R279-V355 VanDerWaalsContact CB-CG1 3.42Å; R279-V355 HydrophobicContact CG-CG1 4.18Å; R279-C358 HydrophobicContact CG-CB 4.38Å; R279-C358 WeakPolarHBondContact CG-SG 3.45Å
280N92.8Very high86.8Confident5 Ų555.6 Ų55.63%0.02732%0.321CS..EExtended strand (participates in β ladder)trans-88.8128.3175.4-66.2-44.2000110.4S261 A265 M282 R323 V355 D356S261-N280 PolarHBondContact OG-OD1 2.8Å; A265-N280 HydrophobicContact CB-CB 4.37Å; A265-N280 VanDerWaalsContact CB-CG 3.47Å; A265-N280 WeakPolarHBondContact CB-ND2 3.46Å; A265-N280 WeakPolarHBondContact CB-OD1 3.34Å; N280-M282 HydrophobicContact CB-SD 3.89Å; N280-M282 PolarHBondContact O-N 2.98Å; N280-R323 PolarHBondContact OD1-NH1 3.16Å; N280-V355 WeakPolarHBondContact O-CA 3.48Å; N280-D356 HydrophobicContact CB-CB 4.35Å; N280-D356 PolarHBondContact O-N 2.71Å
281I94.6Very high88.1Confident4 Ų453 Ų532%0.02133%0.325CS..EExtended strand (participates in β ladder)trans-77.7115.5164.6-61.1163.6000107.1D260 S261 W262 L285 W305 E350 A353 V355D260-I281 HydrophobicContact CB-CD1 3.92Å; D260-I281 HydrophobicContact CB-CG1 3.9Å; S261-I281 PolarHBondContact O-N 2.78Å; W262-I281 HydrophobicContact CB-CD1 4.21Å; W262-I281 HydrophobicContact CE3-CB 3.83Å; W262-I281 HydrophobicContact CE3-CG2 3.58Å; W262-I281 HydrophobicContact CZ3-CB 4.44Å; W262-I281 HydrophobicContact CZ3-CG2 3.81Å; I281-L285 HydrophobicContact CD1-CD2 4.38Å; I281-L285 HydrophobicContact CG2-CD1 4Å; I281-L285 HydrophobicContact CG2-CD2 3.88Å; I281-L285 HydrophobicContact CG2-CG 3.71Å; I281-W305 HydrophobicContact CD1-CH2 3.58Å; I281-W305 HydrophobicContact CD1-CZ2 4.45Å; I281-W305 HydrophobicContact CD1-CZ3 3.9Å; I281-E350 HydrophobicContact CD1-CG 4.06Å; I281-E350 WeakPolarHBondContact CD1-OE1 3.46Å; I281-A353 HydrophobicContact CG2-CB 4.08Å; I281-V355 HydrophobicContact CG1-CG2 4.17Å
282M92.3Very high89.1Confident87 Ų8756.4 Ų56.443%0.42934%0.342SS..EExtended strand (participates in β ladder)trans-89.5-40.2-173.2-61-58.5-66.500112.3N280 Q354 D356N280-M282 HydrophobicContact CB-SD 3.89Å; N280-M282 PolarHBondContact O-N 2.98Å; M282-Q354 WeakPolarHBondContact CB-O 3.16Å; M282-Q354 PolarHBondContact N-O 3.3Å; M282-D356 HydrophobicContact CG-CB 4.26Å; M282-D356 HydrophobicContact SD-CB 4.46Å
283S95.1Very high90.5Very high44 Ų4457.8 Ų57.831%0.30834%0.34SS..EExtended strand (participates in β ladder)trans-166.6179.7-17968.20000111.4A353 Q354S283-A353 CarbonylContact O-C 3.51Å; S283-A353 VanDerWaalsContact O-CA 3.25Å; S283-A353 WeakPolarHBondContact O-CA 3.4Å; S283-Q354 PolarHBondContact O-N 2.95Å
284G95.9Very high91.6Very high15 Ų1551.1 Ų51.116%0.15530%0.304CS..  trans84.58.6168.300000115.3T352G284-T352 CarbonylContact O-C 3.58Å; G284-T352 PolarHBondContact O-OG1 3.05Å
285L97.2Very high92.3Very high0 Ų048.2 Ų48.20%030%0.297CS..  trans-69.8143.5170.9-69.4-176.3000111.5W262 I281 M295 L296 W305 T349 E350 A353W262-L285 HydrophobicContact CB-CD1 4.31Å; W262-L285 HydrophobicContact CD2-CD1 3.22Å; W262-L285 HydrophobicContact CD2-CG 4.43Å; W262-L285 HydrophobicContact CE3-CD1 3.35Å; W262-L285 HydrophobicContact CE3-CG 4.16Å; W262-L285 HydrophobicContact CG-CD1 3.72Å; W262-L285 HydrophobicContact CH2-CD1 3.98Å; W262-L285 HydrophobicContact CH2-CG 4.44Å; W262-L285 HydrophobicContact CZ2-CD1 3.91Å; W262-L285 HydrophobicContact CZ3-CD1 3.72Å; W262-L285 HydrophobicContact CZ3-CG 4.16Å; I281-L285 HydrophobicContact CD1-CD2 4.38Å; I281-L285 HydrophobicContact CG2-CD1 4Å; I281-L285 HydrophobicContact CG2-CD2 3.88Å; I281-L285 HydrophobicContact CG2-CG 3.71Å; L285-M295 WeakPolarHBondContact O-CE 3.28Å; L285-L296 HydrophobicContact CB-CB 3.96Å; L285-L296 HydrophobicContact CB-CD1 4.12Å; L285-L296 PolarHBondContact O-N 3.24Å; L285-W305 HydrophobicContact CD1-CH2 4.25Å; L285-W305 HydrophobicContact CD1-CZ2 3.7Å; L285-T349 WeakPolarHBondContact CA-O 3.06Å; L285-T349 HydrophobicContact CB-CG2 4.12Å; L285-T349 HydrophobicContact CD2-CG2 3.97Å; L285-T349 WeakPolarHBondContact CD2-O 3.47Å; L285-T349 HydrophobicContact CG-CG2 4.47Å; L285-E350 HydrophobicContact CD2-CB 4.29Å; L285-E350 HydrophobicContact CD2-CG 3.55Å; L285-A353 HydrophobicContact CD2-CB 3.97Å
286H96.2Very high92.7Very high11 Ų1144.2 Ų44.25%0.05126%0.263CS..EExtended strand (participates in β ladder)trans-150.9144.917662.9-82.2000111.7T288 T294 M295 T349 T352H286-T288 PolarHBondContact CD2-OG1 3.16Å; H286-T294 CarbonylContact C-O 3.48Å; H286-T294 VanDerWaalsContact CA-O 3.23Å; H286-T294 WeakPolarHBondContact CA-O 3.25Å; H286-M295 HydrophobicContact CB-CE 4.37Å; H286-M295 HydrophobicContact CB-SD 3.73Å; H286-T349 PolarHBondContact N-O 2.94Å; H286-T349 VanDerWaalsContact O-CA 3.23Å; H286-T349 WeakPolarHBondContact O-CA 3.15Å; H286-T349 VanDerWaalsContact O-CG2 3.25Å; H286-T349 WeakPolarHBondContact O-CG2 3.43Å; H286-T352 PolarHBondContact CE1-OG1 3.11Å; H286-T352 PolarHBondContact ND1-OG1 3.02Å
287L95.7Very high92.9Very high0 Ų046.4 Ų46.40%027%0.272CS..EExtended strand (participates in β ladder)trans-95.5133.5170-59.1-176.9000109.4Y44 M46 F66 W77 T294 L296 T349Y44-L287 HydrophobicContact CD1-CD1 4.34Å; Y44-L287 HydrophobicContact CD2-CD1 4.34Å; Y44-L287 HydrophobicContact CG-CD1 3.95Å; M46-L287 HydrophobicContact SD-CD1 3.75Å; F66-L287 HydrophobicContact CB-CD1 3.78Å; F66-L287 HydrophobicContact CD1-CB 4.25Å; F66-L287 HydrophobicContact CD2-CB 4.28Å; F66-L287 HydrophobicContact CD2-CD1 3.64Å; F66-L287 HydrophobicContact CE1-CB 4.3Å; F66-L287 HydrophobicContact CE2-CB 4.33Å; F66-L287 HydrophobicContact CE2-CD1 4.35Å; F66-L287 HydrophobicContact CG-CB 4.24Å; F66-L287 HydrophobicContact CG-CD1 3.75Å; F66-L287 HydrophobicContact CZ-CB 4.34Å; W77-L287 HydrophobicContact CD2-CD2 3.94Å; W77-L287 HydrophobicContact CG-CD2 4.13Å; W77-L287 HydrophobicContact CZ2-CD2 3.93Å; L287-T294 PolarHBondContact N-O 2.85Å; L287-T294 PolarHBondContact O-N 2.47Å; L287-L296 HydrophobicContact CD2-CD1 4.23Å; L287-L296 HydrophobicContact CG-CD1 4.03Å; L287-T349 HydrophobicContact CD2-CG2 3.8Å; L287-T349 WeakPolarHBondContact CD2-OG1 3.45Å
288T92.7Very high93Very high56 Ų5647.7 Ų47.734%0.34427%0.272SS..EExtended strand (participates in β ladder)trans-114.9131-179.8-56.70000110.3H286 D292 M293H286-T288 PolarHBondContact CD2-OG1 3.16Å; T288-D292 WeakPolarHBondContact CA-O 3.39Å; T288-M293 HydrophobicContact CG2-CG 4.37Å
289H92.2Very high93Very high74 Ų7453.6 Ų53.634%0.34330%0.304SS..EExtended strand (participates in β ladder)trans-142120.7169.8-175.773.4000110.2F66 W77 T78 K79 G291 D292F66-H289 HydrophobicContact CD1-CB 4.28Å; F66-H289 HydrophobicContact CE1-CB 3.79Å; W77-H289 PolarHBondContact O-ND1 3.07Å; T78-H289 WeakPolarHBondContact CA-ND1 3.41Å; K79-H289 HydrophobicContact CB-CB 4Å; H289-G291 PolarHBondContact O-N 2.67Å; H289-D292 PolarHBondContact N-O 3.41Å; H289-D292 VanDerWaalsContact N-O 3.07Å; H289-D292 PolarHBondContact O-N 2.98Å
290G88.2Confident93.2Very high72 Ų7252.2 Ų52.274%0.74230%0.304SS*.THydrogen-bonded Turntrans64.6-127.2-170.200000110.7
291G86.2Confident93.3Very high77 Ų7752 Ų5279%0.79430%0.303SS*.THydrogen-bonded Turntrans-92.7-4.2175.300000114.6H289H289-G291 PolarHBondContact O-N 2.67Å
292D87.9Confident93.4Very high92 Ų9252.7 Ų52.749%0.49231%0.307SS..EExtended strand (participates in β ladder)trans-94.4134.6-172.9-61.7-27.5000111T288 H289T288-D292 WeakPolarHBondContact CA-O 3.39Å; H289-D292 PolarHBondContact N-O 3.41Å; H289-D292 VanDerWaalsContact N-O 3.07Å; H289-D292 PolarHBondContact O-N 2.98Å
293M90.1Very high93.6Very high123 Ų12348.6 Ų48.661%0.60629%0.287SS*.EExtended strand (participates in β ladder)trans-111.2132.5171.4-69.6-177.4-7100109.8T288T288-M293 HydrophobicContact CG2-CG 4.37Å
294T92.4Very high93.7Very high5 Ų546.8 Ų46.83%0.03127%0.273CS..EExtended strand (participates in β ladder)trans-120.8116.7176.1-51.70000110.1M46 F53 H286 L287M46-T294 HydrophobicContact CE-CG2 3.55Å; F53-T294 HydrophobicContact CE2-CG2 4.22Å; F53-T294 HydrophobicContact CZ-CG2 4.45Å; H286-T294 CarbonylContact C-O 3.48Å; H286-T294 VanDerWaalsContact CA-O 3.23Å; H286-T294 WeakPolarHBondContact CA-O 3.25Å; L287-T294 PolarHBondContact N-O 2.85Å; L287-T294 PolarHBondContact O-N 2.47Å
295M94.1Very high93.8Very high67 Ų6746 Ų4633%0.3327%0.266SS..EExtended strand (participates in β ladder)trans-70.8145-177-61.5-55.1-59.900112.3L285 H286 Y297L285-M295 WeakPolarHBondContact O-CE 3.28Å; H286-M295 HydrophobicContact CB-CE 4.37Å; H286-M295 HydrophobicContact CB-SD 3.73Å; M295-Y297 HydrophobicContact CB-CD2 4.45Å; M295-Y297 HydrophobicContact CB-CE1 4.37Å; M295-Y297 HydrophobicContact CB-CE2 3.65Å
296L95.7Very high93.8Very high5 Ų546 Ų463%0.02627%0.266CS..  trans-109.5132.7170.3-67.6167.6000109.1Y44 M46 W262 L285 L287 T349Y44-L296 HydrophobicContact CD1-CD2 4.15Å; Y44-L296 HydrophobicContact CE1-CD1 4.11Å; Y44-L296 HydrophobicContact CE1-CD2 3.49Å; Y44-L296 VanDerWaalsContact CE1-CD2 3.49Å; Y44-L296 HydrophobicContact CE1-CG 4.46Å; Y44-L296 HydrophobicContact CE2-CD1 4.13Å; M46-L296 HydrophobicContact CE-CD2 3.43Å; M46-L296 VanDerWaalsContact CE-CD2 3.43Å; M46-L296 HydrophobicContact CE-CG 4.29Å; M46-L296 HydrophobicContact SD-CD2 3.96Å; W262-L296 HydrophobicContact CZ2-CB 4.35Å; L285-L296 HydrophobicContact CB-CB 3.96Å; L285-L296 HydrophobicContact CB-CD1 4.12Å; L285-L296 PolarHBondContact O-N 3.24Å; L287-L296 HydrophobicContact CD2-CD1 4.23Å; L287-L296 HydrophobicContact CG-CD1 4.03Å; L296-T349 HydrophobicContact CD1-CG2 4.2Å
297Y95.3Very high93.9Very high136 Ų13645.5 Ų45.553%0.53326%0.263SS..  trans-121.1131.1-179.5-57.3-82.4000110.1M295 D299 T300 D301M295-Y297 HydrophobicContact CB-CD2 4.45Å; M295-Y297 HydrophobicContact CB-CE1 4.37Å; M295-Y297 HydrophobicContact CB-CE2 3.65Å; Y297-D299 VanDerWaalsContact C-N 3.27Å; Y297-D299 VanDerWaalsContact CB-OD1 3.28Å; Y297-D299 WeakPolarHBondContact CB-OD1 2.79Å; Y297-D299 PolarHBondContact O-N 3.15Å; Y297-T300 PolarHBondContact O-N 3.11Å; Y297-T300 VanDerWaalsContact O-N 3.15Å; Y297-T300 PolarHBondContact O-OG1 3.35Å; Y297-D301 WeakPolarHBondContact O-CB 3.29Å; Y297-D301 PolarHBondContact O-N 2.65Å
298R93.7Very high94Very high45 Ų4545.5 Ų45.517%0.1726%0.263CS..G310 helixtrans-61.5-34.4-170.5179.566.8-69.3159.73.8113.6W262 T300 D301 S303W262-R298 VanDerWaalsContact C-NH1 3.34Å; W262-R298 HydrophobicContact CH2-CB 3.75Å; W262-R298 HydrophobicContact CZ2-CB 4.21Å; W262-R298 HydrophobicContact CZ3-CB 4.25Å; W262-R298 VanDerWaalsContact NE1-CZ 3.33Å; W262-R298 PolarHBondContact O-NH1 3.04Å; R298-T300 VanDerWaalsContact C-N 3.32Å; R298-D301 VanDerWaalsContact NH2-C 3.26Å; R298-D301 VanDerWaalsContact NH2-CB 3.32Å; R298-D301 PolarHBondContact NH2-O 2.9Å; R298-D301 IonicContact NH2-OD1 2.79Å; R298-D301 PolarHBondContact NH2-OD1 3.12Å; R298-D301 IonicContact NH2-OD2 2.81Å; R298-S303 PolarHBondContact NH1-O 2.94Å; R298-S303 PolarHBondContact NH2-O 3.44Å
299D93.4Very high94.1Very high128 Ų12845.2 Ų45.268%0.68426%0.261SS*.G310 helixtrans-73.7-21.2-178.862.7-27.3000113.7Y297Y297-D299 VanDerWaalsContact C-N 3.27Å; Y297-D299 VanDerWaalsContact CB-OD1 3.28Å; Y297-D299 WeakPolarHBondContact CB-OD1 2.79Å; Y297-D299 PolarHBondContact O-N 3.15Å
300T95.1Very high94.2Very high50 Ų5044.6 Ų44.631%0.30726%0.261SS..G310 helixtrans-111.615.2178.360.70000112.7K158 A159 Y297 R298K158-T300 CarbonylContact C-O 3.54Å; K158-T300 VanDerWaalsContact CA-O 3.27Å; K158-T300 WeakPolarHBondContact CA-O 3.45Å; K158-T300 VanDerWaalsContact CB-O 3.31Å; K158-T300 WeakPolarHBondContact CB-O 3.2Å; A159-T300 PolarHBondContact N-O 3.38Å; Y297-T300 PolarHBondContact O-N 3.11Å; Y297-T300 VanDerWaalsContact O-N 3.15Å; Y297-T300 PolarHBondContact O-OG1 3.35Å; R298-T300 VanDerWaalsContact C-N 3.32Å
301D96.1Very high94.4Very high1 Ų148.5 Ų48.51%0.00526%0.257CS..BIsolated β-bridgetrans-129.4122.2-176.3-172.6-15.2000109.4Y44 A159 W262 Y297 R298 S303Y44-D301 PolarHBondContact OH-OD2 2.85Å; A159-D301 HydrophobicContact CB-CB 3.95Å; W262-D301 HydrophobicContact CZ2-CB 4.42Å; W262-D301 PolarHBondContact NE1-OD2 3.41Å; Y297-D301 WeakPolarHBondContact O-CB 3.29Å; Y297-D301 PolarHBondContact O-N 2.65Å; R298-D301 VanDerWaalsContact NH2-C 3.26Å; R298-D301 VanDerWaalsContact NH2-CB 3.32Å; R298-D301 PolarHBondContact NH2-O 2.9Å; R298-D301 IonicContact NH2-OD1 2.79Å; R298-D301 PolarHBondContact NH2-OD1 3.12Å; R298-D301 IonicContact NH2-OD2 2.81Å; D301-S303 VanDerWaalsContact CG-OG 3.24Å; D301-S303 WeakPolarHBondContact OD1-CA 3.19Å; D301-S303 WeakPolarHBondContact OD1-CB 3.43Å; D301-S303 PolarHBondContact OD1-N 2.77Å; D301-S303 PolarHBondContact OD1-OG 3.15Å; D301-S303 PolarHBondContact OD2-OG 2.82Å
302D95.4Very high94.7Very high19 Ų1951.5 Ų51.510%0.10226%0.255CS..  trans-97.1-1.8177.2-76.3-42.5000113K158 A159 Q160 K264 R304K158-D302 VanDerWaalsContact CD-OD2 3.26Å; K158-D302 WeakPolarHBondContact CD-OD2 3.47Å; A159-D302 PolarHBondContact O-N 3.49Å; Q160-D302 PolarHBondContact NE2-OD2 3.39Å; K264-D302 IonicContact NZ-OD1 2.7Å; D302-R304 PolarHBondContact O-NH1 2.88Å
303S96.4Very high95.1Very high0 Ų053 Ų530%025%0.254CS..  trans-66.9147.1177.971.60000112.8Y44 D138 L161 W262 R298 D301Y44-S303 PolarHBondContact OH-OG 2.79Å; D138-S303 WeakPolarHBondContact OD2-CA 3.25Å; D138-S303 PolarHBondContact OD2-N 2.89Å; L161-S303 VanDerWaalsContact CB-CB 3.41Å; W262-S303 PolarHBondContact NE1-OG 2.75Å; R298-S303 PolarHBondContact NH1-O 2.94Å; R298-S303 PolarHBondContact NH2-O 3.44Å; D301-S303 VanDerWaalsContact CG-OG 3.24Å; D301-S303 WeakPolarHBondContact OD1-CA 3.19Å; D301-S303 WeakPolarHBondContact OD1-CB 3.43Å; D301-S303 PolarHBondContact OD1-N 2.77Å; D301-S303 PolarHBondContact OD1-OG 3.15Å; D301-S303 PolarHBondContact OD2-OG 2.82Å
304R97.1Very high95.4Very high6 Ų648.2 Ų48.22%0.02323%0.232CC..  trans-137.7118.4-179.1-57.4175.4-171.875.68.8110W262 T263 D302 T319 S321 D322W262-R304 VanDerWaalsContact O-CA 3.3Å; W262-R304 WeakPolarHBondContact O-CA 3.45Å; T263-R304 HydrophobicContact CG2-CB 4.05Å; T263-R304 HydrophobicContact CG2-CG 4.46Å; D302-R304 PolarHBondContact O-NH1 2.88Å; R304-T319 HydrophobicContact CB-CG2 3.71Å; R304-T319 WeakPolarHBondContact CB-O 3.27Å; R304-T319 WeakPolarHBondContact O-CG2 3.34Å; R304-T319 PolarHBondContact O-N 3.35Å; R304-T319 VanDerWaalsContact O-N 3.13Å; R304-S321 WeakPolarHBondContact CD-O 3.38Å; R304-D322 WeakPolarHBondContact CD-OD1 3.49Å; R304-D322 IonicContact CZ-OD2 3.7Å; R304-D322 IonicContact NE-OD1 3.95Å; R304-D322 PolarHBondContact NE-OD1 3.19Å; R304-D322 IonicContact NE-OD2 2.75Å; R304-D322 PolarHBondContact NE-OD2 2.98Å; R304-D322 IonicContact NH2-OD2 2.77Å; R304-D322 PolarHBondContact NH2-OD2 2.69Å
305W98.2Very high95.7Very high0 Ų048.3 Ų48.30%023%0.232CC..EExtended strand (participates in β ladder)trans-153.5164.6-179.656.1-96.1000112.6Y44 L161 W262 I281 L285 L307 W316 C317 F346 E350Y44-W305 AromaticContact CE2-NE1 3.88Å; L161-W305 HydrophobicContact CD2-CB 4.19Å; L161-W305 HydrophobicContact CD2-CG 4.42Å; W262-W305 HydrophobicContact CB-CD2 3.76Å; W262-W305 HydrophobicContact CB-CE3 4.19Å; W262-W305 HydrophobicContact CB-CG 4.29Å; W262-W305 HydrophobicContact CB-CH2 3.92Å; W262-W305 HydrophobicContact CB-CZ2 3.48Å; W262-W305 VanDerWaalsContact CB-CZ2 3.48Å; W262-W305 HydrophobicContact CB-CZ3 4.24Å; W262-W305 AromaticContact CD1-CD1 3.79Å; W262-W305 AromaticContact CD1-CE2 3.73Å; W262-W305 AromaticContact CD1-NE1 3.17Å; W262-W305 AromaticContact CG-CE2 3.76Å; W262-W305 AromaticContact CG-CZ2 3.84Å; W262-W305 HydrophobicContact CG-CZ2 3.84Å; W262-W305 AromaticContact CG-NE1 3.68Å; W262-W305 PolarHBondContact N-O 2.71Å; W262-W305 PolarHBondContact O-N 3.29Å; W262-W305 VanDerWaalsContact O-N 3.16Å; I281-W305 HydrophobicContact CD1-CH2 3.58Å; I281-W305 HydrophobicContact CD1-CZ2 4.45Å; I281-W305 HydrophobicContact CD1-CZ3 3.9Å; L285-W305 HydrophobicContact CD1-CH2 4.25Å; L285-W305 HydrophobicContact CD1-CZ2 3.7Å; W305-L307 HydrophobicContact CE3-CB 4.24Å; W305-L307 HydrophobicContact CZ3-CB 3.74Å; W305-W316 HydrophobicContact CB-CZ2 3.81Å; W305-W316 AromaticContact CD2-NE1 3.92Å; W305-W316 AromaticContact CE3-NE1 3.91Å; W305-W316 HydrophobicContact CG-CZ2 4.37Å; W305-W316 AromaticContact CG-NE1 3.89Å; W305-C317 CarbonylContact C-O 3.54Å; W305-C317 WeakPolarHBondContact CA-O 3.33Å; W305-C317 WeakPolarHBondContact CB-O 3.49Å; W305-F346 HydrophobicContact CD2-CD1 4.02Å; W305-F346 AromaticContact CD2-CE1 3.8Å; W305-F346 HydrophobicContact CD2-CE1 3.8Å; W305-F346 AromaticContact CE2-CD1 3.93Å; W305-F346 AromaticContact CE2-CE1 3.67Å; W305-F346 HydrophobicContact CE3-CD1 4.02Å; W305-F346 HydrophobicContact CE3-CE1 4.25Å; W305-F346 HydrophobicContact CG-CE1 4.19Å; W305-F346 AromaticContact CH2-CD1 3.92Å; W305-F346 HydrophobicContact CH2-CD1 3.92Å; W305-F346 HydrophobicContact CH2-CE1 4.49Å; W305-F346 AromaticContact CZ2-CD1 3.87Å; W305-F346 HydrophobicContact CZ2-CD1 3.87Å; W305-F346 HydrophobicContact CZ2-CE1 4.02Å; W305-F346 AromaticContact CZ3-CD1 4Å; W305-F346 HydrophobicContact CZ3-CD1 4Å; W305-F346 AromaticContact NE1-CE1 3.94Å; W305-E350 HydrophobicContact CH2-CG 4.31Å; W305-E350 WeakPolarHBondContact CH2-OE1 3.41Å; W305-E350 WeakPolarHBondContact CZ3-OE1 3.41Å
306L97.9Very high95.9Very high0 Ų045.1 Ų45.10%022%0.217CC..EExtended strand (participates in β ladder)trans-125.2148.1172.1-57108000111.4F247 I251 Y259 D260 V278 W316 C317 T319F247-L306 HydrophobicContact CB-CD2 4.32Å; F247-L306 HydrophobicContact CD1-CD1 3.7Å; F247-L306 HydrophobicContact CD1-CD2 3.49Å; F247-L306 VanDerWaalsContact CD1-CD2 3.49Å; F247-L306 HydrophobicContact CD1-CG 4.01Å; F247-L306 HydrophobicContact CE1-CD1 3.77Å; F247-L306 HydrophobicContact CE1-CD2 4.21Å; F247-L306 HydrophobicContact CE1-CG 4.27Å; F247-L306 HydrophobicContact CG-CD2 4.3Å; I251-L306 HydrophobicContact CD1-CD1 4.06Å; Y259-L306 HydrophobicContact CD1-CB 3.73Å; Y259-L306 HydrophobicContact CD1-CD2 4.43Å; Y259-L306 HydrophobicContact CE1-CB 4.43Å; Y259-L306 HydrophobicContact CG-CB 4.36Å; Y259-L306 HydrophobicContact CG-CD2 4.27Å; D260-L306 CarbonylContact O-C 3.58Å; D260-L306 WeakPolarHBondContact O-CA 3.18Å; V278-L306 HydrophobicContact CG1-CD2 3.94Å; L306-W316 CarbonylContact O-C 3.51Å; L306-W316 WeakPolarHBondContact O-CA 3.43Å; L306-C317 HydrophobicContact CB-CB 4.26Å; L306-C317 HydrophobicContact CD1-CB 3.86Å; L306-C317 PolarHBondContact N-O 3.25Å; L306-C317 PolarHBondContact O-N 3.29Å; L306-T319 HydrophobicContact CD1-CG2 4.03Å
307L98.4Very high96.1Very high0 Ų044.9 Ų44.90%022%0.215CC..EExtended strand (participates in β ladder)trans-128.1128.1173-173.471.2000109.6Y259 D260 W305 W316 H343 F346 L347 E350Y259-L307 CarbonylContact C-O 3.59Å; Y259-L307 VanDerWaalsContact CA-O 3.27Å; Y259-L307 WeakPolarHBondContact CA-O 3.3Å; Y259-L307 VanDerWaalsContact CD1-C 3.43Å; D260-L307 PolarHBondContact N-O 2.94Å; D260-L307 PolarHBondContact O-N 2.94Å; W305-L307 HydrophobicContact CE3-CB 4.24Å; W305-L307 HydrophobicContact CZ3-CB 3.74Å; L307-W316 HydrophobicContact CD1-CB 4.34Å; L307-H343 HydrophobicContact CD1-CB 4.46Å; L307-H343 WeakPolarHBondContact CD1-CD2 3.46Å; L307-F346 HydrophobicContact CD1-CB 3.66Å; L307-F346 HydrophobicContact CD2-CB 3.85Å; L307-F346 HydrophobicContact CG-CB 4.33Å; L307-L347 HydrophobicContact CD2-CB 4.47Å; L307-L347 HydrophobicContact CD2-CD2 3.65Å; L307-L347 HydrophobicContact CD2-CG 3.94Å; L307-E350 WeakPolarHBondContact CB-OE1 3.37Å; L307-E350 VanDerWaalsContact CD2-CD 3.5Å; L307-E350 WeakPolarHBondContact CD2-OE1 3.48Å
308S97.8Very high96.2Very high0 Ų038.6 Ų38.60%019%0.191CC..EExtended strand (participates in β ladder)trans-68140.5174.762.90000110.5T258 R313 I315 H343T258-S308 WeakPolarHBondContact O-CA 3.43Å; S308-R313 WeakPolarHBondContact CB-O 3.24Å; S308-R313 PolarHBondContact OG-O 2.79Å; S308-I315 PolarHBondContact N-O 2.7Å; S308-I315 PolarHBondContact OG-N 2.81Å; S308-I315 PolarHBondContact OG-O 2.83Å; S308-H343 PolarHBondContact O-CE1 2.99Å; S308-H343 PolarHBondContact O-NE2 2.79Å; S308-H343 PolarHBondContact OG-CD2 2.96Å; S308-H343 PolarHBondContact OG-NE2 3.12Å
309T94.8Very high96.4Very high49 Ų4936.5 Ų36.530%0.30118%0.183SC..SBendtrans-82.8-21.9178.261.50000112T258 D260 R279 K311T258-T309 WeakPolarHBondContact CB-OG1 3.43Å; T258-T309 HydrophobicContact CG2-CG2 4.08Å; T258-T309 WeakPolarHBondContact CG2-OG1 3.49Å; T258-T309 PolarHBondContact O-N 3.48Å; T258-T309 PolarHBondContact O-OG1 3.43Å; D260-T309 HydrophobicContact CB-CG2 4.49Å; D260-T309 WeakPolarHBondContact OD1-CG2 3.27Å; R279-T309 VanDerWaalsContact NH2-CG2 3.28Å; T309-K311 PolarHBondContact O-N 2.92Å
310N93.2Very high96.5Very high62 Ų6230.4 Ų30.433%0.33215%0.15SC..  trans-80.4112.8176.4-173.6-5.9000111T257 D312 R313T257-N310 VanDerWaalsContact OG1-CB 3.26Å; T257-N310 WeakPolarHBondContact OG1-CB 3.3Å; N310-D312 PolarHBondContact O-N 3.06Å; N310-D312 WeakPolarHBondContact OD1-CB 3.33Å; N310-D312 PolarHBondContact OD1-N 2.54Å; N310-R313 HydrophobicContact CB-CB 4.34Å; N310-R313 CarbonylContact O-C 3.56Å; N310-R313 VanDerWaalsContact O-C 3.27Å; N310-R313 PolarHBondContact O-N 3.04Å; N310-R313 VanDerWaalsContact O-O 3.09Å
311K92.5Very high96.4Very high154 Ų15428.1 Ų28.167%0.6714%0.136SC*.THydrogen-bonded Turntrans-65.8-22.6178.9-62.9179.3-176.71740113.6T309 R313 L347T309-K311 PolarHBondContact O-N 2.92Å; K311-R313 PolarHBondContact O-N 2.79Å; K311-L347 HydrophobicContact CG-CD1 4.2Å
312D94.2Very high96.2Very high139 Ų13928.5 Ų28.574%0.74314%0.138SC*.THydrogen-bonded Turntrans-79.1-9.5175.5-59.5-35.6000112.3N310N310-D312 PolarHBondContact O-N 3.06Å; N310-D312 WeakPolarHBondContact OD1-CB 3.33Å; N310-D312 PolarHBondContact OD1-N 2.54Å
313R95Very high95.9Very high124 Ų12428 Ų2847%0.46814%0.135SC..SBendtrans-126.770.6174.1-68.1-62.9-147.6-155.81.9109.2T257 S308 N310 K311 I315T257-R313 HydrophobicContact CG2-CB 4.45Å; S308-R313 WeakPolarHBondContact CB-O 3.24Å; S308-R313 PolarHBondContact OG-O 2.79Å; N310-R313 HydrophobicContact CB-CB 4.34Å; N310-R313 CarbonylContact O-C 3.56Å; N310-R313 VanDerWaalsContact O-C 3.27Å; N310-R313 PolarHBondContact O-N 3.04Å; N310-R313 VanDerWaalsContact O-O 3.09Å; K311-R313 PolarHBondContact O-N 2.79Å; R313-I315 VanDerWaalsContact C-N 3.26Å; R313-I315 HydrophobicContact CB-CD1 4.5Å; R313-I315 PolarHBondContact O-N 2.79Å
314P97.1Very high95.6Very high22 Ų2229.6 Ų29.614%0.14315%0.145CC..  trans-76.172.4-168.632.7-37.2000112.3E338 N339 H343P314-E338 HydrophobicContact CG-CG 4.12Å; P314-E338 CarbonylContact O-C 3.56Å; P314-E338 WeakPolarHBondContact O-CA 3.42Å; P314-N339 PolarHBondContact O-N 2.9Å; P314-H343 VanDerWaalsContact C-CD2 3.5Å; P314-H343 VanDerWaalsContact CA-CD2 3.45Å; P314-H343 WeakPolarHBondContact CA-CD2 3.33Å; P314-H343 HydrophobicContact CB-CB 3.59Å
315I98.4Very high95.1Very high8 Ų834.3 Ų34.34%0.04117%0.167CC..EExtended strand (participates in β ladder)trans-103.1130.4-174.4-58.7170.7000109T255 Y259 S308 R313 C336 I337 E338T255-I315 HydrophobicContact CG2-CD1 4.03Å; Y259-I315 HydrophobicContact CE1-CB 4.31Å; Y259-I315 HydrophobicContact CE1-CG2 4.15Å; Y259-I315 WeakPolarHBondContact OH-CG2 3.33Å; S308-I315 PolarHBondContact N-O 2.7Å; S308-I315 PolarHBondContact OG-N 2.81Å; S308-I315 PolarHBondContact OG-O 2.83Å; R313-I315 VanDerWaalsContact C-N 3.26Å; R313-I315 HydrophobicContact CB-CD1 4.5Å; R313-I315 PolarHBondContact O-N 2.79Å; I315-C336 HydrophobicContact CG2-CB 3.93Å; I315-I337 WeakPolarHBondContact CA-O 3.49Å; I315-E338 HydrophobicContact CG1-CB 4.24Å; I315-E338 HydrophobicContact CG1-CG 4.12Å
316W98.5Very high94.7Very high0 Ų041.1 Ų41.10%019%0.193CC..EExtended strand (participates in β ladder)trans-122.9142.9168176.388.3000109.4L42 L161 F163 W305 L306 L307 C336 I337 L342 F346L42-W316 HydrophobicContact CD1-CD2 4.48Å; L42-W316 HydrophobicContact CD1-CE3 4.41Å; L42-W316 HydrophobicContact CD1-CH2 3.31Å; L42-W316 HydrophobicContact CD1-CZ2 3.38Å; L42-W316 HydrophobicContact CD1-CZ3 3.87Å; L42-W316 HydrophobicContact CG-CH2 4.31Å; L161-W316 HydrophobicContact CD1-CZ2 4.48Å; L161-W316 HydrophobicContact CD2-CH2 4.14Å; L161-W316 HydrophobicContact CD2-CZ2 3.85Å; F163-W316 HydrophobicContact CB-CH2 4.4Å; F163-W316 HydrophobicContact CD1-CZ3 4.01Å; F163-W316 HydrophobicContact CD2-CZ3 4.1Å; F163-W316 HydrophobicContact CE1-CZ3 4.16Å; F163-W316 HydrophobicContact CE2-CZ3 4.25Å; F163-W316 HydrophobicContact CG-CH2 4.28Å; F163-W316 AromaticContact CG-CZ3 3.99Å; F163-W316 HydrophobicContact CG-CZ3 3.99Å; F163-W316 HydrophobicContact CZ-CZ3 4.28Å; W305-W316 HydrophobicContact CB-CZ2 3.81Å; W305-W316 AromaticContact CD2-NE1 3.92Å; W305-W316 AromaticContact CE3-NE1 3.91Å; W305-W316 HydrophobicContact CG-CZ2 4.37Å; W305-W316 AromaticContact CG-NE1 3.89Å; L306-W316 CarbonylContact O-C 3.51Å; L306-W316 WeakPolarHBondContact O-CA 3.43Å; L307-W316 HydrophobicContact CD1-CB 4.34Å; W316-C336 CarbonylContact O-C 3.5Å; W316-C336 VanDerWaalsContact O-CA 3.25Å; W316-C336 WeakPolarHBondContact O-CA 3.07Å; W316-I337 HydrophobicContact CB-CG2 4.46Å; W316-I337 HydrophobicContact CE3-CG2 3.96Å; W316-I337 PolarHBondContact N-O 2.84Å; W316-I337 PolarHBondContact O-N 3.05Å; W316-L342 HydrophobicContact CB-CD2 3.27Å; W316-L342 HydrophobicContact CD2-CD2 3.76Å; W316-L342 HydrophobicContact CE3-CD1 4.31Å; W316-L342 HydrophobicContact CE3-CD2 4.2Å; W316-L342 HydrophobicContact CG-CD2 3.35Å; W316-F346 AromaticContact CD1-CD1 3.81Å; W316-F346 AromaticContact CD1-CD2 3.81Å; W316-F346 AromaticContact CD1-CE1 4Å; W316-F346 AromaticContact CD1-CE2 3.99Å; W316-F346 AromaticContact CD1-CG 3.71Å; W316-F346 AromaticContact CE2-CE2 3.92Å; W316-F346 AromaticContact CE2-CZ 3.64Å; W316-F346 HydrophobicContact CG-CD2 4.47Å; W316-F346 HydrophobicContact CZ2-CE1 4.39Å; W316-F346 HydrophobicContact CZ2-CE2 4.4Å; W316-F346 AromaticContact CZ2-CZ 3.86Å; W316-F346 HydrophobicContact CZ2-CZ 3.86Å; W316-F346 AromaticContact NE1-CD1 3.47Å; W316-F346 AromaticContact NE1-CD2 3.82Å; W316-F346 AromaticContact NE1-CE1 3.19Å; W316-F346 AromaticContact NE1-CE2 3.55Å; W316-F346 AromaticContact NE1-CG 3.77Å; W316-F346 AromaticContact NE1-CZ 3.23Å
317C98.8Very high94.3Very high0 Ų041.7 Ų41.70%020%0.195CC..EExtended strand (participates in β ladder)trans-129.5129.5-179.8-51.80000111.7W305 L306 A334 V335 C336W305-C317 CarbonylContact C-O 3.54Å; W305-C317 WeakPolarHBondContact CA-O 3.33Å; W305-C317 WeakPolarHBondContact CB-O 3.49Å; L306-C317 HydrophobicContact CB-CB 4.26Å; L306-C317 HydrophobicContact CD1-CB 3.86Å; L306-C317 PolarHBondContact N-O 3.25Å; L306-C317 PolarHBondContact O-N 3.29Å; C317-A334 HydrophobicContact CB-CB 4.34Å; C317-V335 WeakPolarHBondContact CA-O 3.14Å; C317-C336 HydrophobicContact CB-CB 4.02Å; C317-C336 WeakPolarHBondContact CB-SG 3.36Å; C317-C336 WeakPolarHBondContact SG-CB 3.35Å; C317-C336 CovalentContact SG-SG 2.04Å; C317-C336 PolarHBondContact SG-SG 3.38Å
318Y98.6Very high93.9Very high4 Ų444.1 Ų44.12%0.01621%0.206CC..EExtended strand (participates in β ladder)trans-73.1135.9155.1178.3-84.6000107.8L136 H137 L161 F163 A334 V335L136-Y318 HydrophobicContact CB-CD1 4.09Å; L136-Y318 HydrophobicContact CB-CE1 3.88Å; L136-Y318 HydrophobicContact CB-CE2 4.39Å; L136-Y318 HydrophobicContact CB-CG 4.45Å; L136-Y318 HydrophobicContact CD1-CD1 3.98Å; L136-Y318 HydrophobicContact CD1-CE1 4.42Å; H137-Y318 WeakPolarHBondContact CA-OH 3.42Å; H137-Y318 PolarHBondContact O-OH 2.8Å; L161-Y318 HydrophobicContact CD2-CD2 3.66Å; L161-Y318 HydrophobicContact CD2-CE2 4.13Å; L161-Y318 HydrophobicContact CG-CD2 4.09Å; L161-Y318 HydrophobicContact CG-CE2 4.29Å; F163-Y318 HydrophobicContact CB-CD2 4.26Å; Y318-A334 CarbonylContact O-C 3.57Å; Y318-A334 WeakPolarHBondContact O-CA 3.3Å; Y318-V335 PolarHBondContact N-O 2.04Å; Y318-V335 PolarHBondContact O-N 3.2Å
319T97.5Very high93.6Very high0 Ų047.8 Ų47.80%023%0.231CC..EExtended strand (participates in β ladder)trans-127.5143.9173173.30000110.3F247 T263 R304 L306 S321 S333F247-T319 HydrophobicContact CE1-CG2 3.9Å; F247-T319 HydrophobicContact CZ-CG2 4.37Å; T263-T319 HydrophobicContact CG2-CG2 4.19Å; R304-T319 HydrophobicContact CB-CG2 3.71Å; R304-T319 WeakPolarHBondContact CB-O 3.27Å; R304-T319 WeakPolarHBondContact O-CG2 3.34Å; R304-T319 PolarHBondContact O-N 3.35Å; R304-T319 VanDerWaalsContact O-N 3.13Å; L306-T319 HydrophobicContact CD1-CG2 4.03Å; T319-S321 PolarHBondContact OG1-N 2.84Å; T319-S333 WeakPolarHBondContact CA-O 3.43Å; T319-S333 PolarHBondContact OG1-O 2.88Å; T319-S333 VanDerWaalsContact OG1-O 3.11Å
320N94.7Very high93.4Very high1 Ų147.4 Ų47.41%0.00523%0.227CC..SBendtrans-81.9-1.6172.378.91000112.2R119 S121 E182 S332 S333R119-N320 WeakPolarHBondContact CD-O 3.5Å; R119-N320 WeakPolarHBondContact CG-O 3.35Å; R119-N320 PolarHBondContact NE-O 3.48Å; R119-N320 PolarHBondContact NH1-O 3.1Å; S121-N320 WeakPolarHBondContact OG-CB 3.26Å; E182-N320 PolarHBondContact OE2-ND2 2.85Å; N320-S332 VanDerWaalsContact OD1-CA 3.28Å; N320-S332 WeakPolarHBondContact OD1-CA 3.5Å; N320-S333 PolarHBondContact N-O 2.98Å; N320-S333 PolarHBondContact ND2-N 3.36Å; N320-S333 PolarHBondContact ND2-OG 2.91Å; N320-S333 VanDerWaalsContact ND2-OG 3.16Å; N320-S333 PolarHBondContact OD1-N 2.79Å; N320-S333 PolarHBondContact OD1-O 3.34Å
321S93.1Very high93.4Very high2 Ų245.5 Ų45.51%0.01422%0.217CC..  trans-122.5149.2-165.4-170.70000115.1R119 F247 R304 T319R119-S321 VanDerWaalsContact NH1-CB 3.27Å; R119-S321 PolarHBondContact NH1-OG 3.41Å; R119-S321 VanDerWaalsContact NH1-OG 3.17Å; F247-S321 WeakPolarHBondContact CZ-O 3.43Å; R304-S321 WeakPolarHBondContact CD-O 3.38Å; T319-S321 PolarHBondContact OG1-N 2.84Å
322D92.9Very high93.5Very high8 Ų838.2 Ų38.24%0.04319%0.185CC..  trans-91163.3168.3-73.2-51.2000111.4F247 K264 R304 T324 E327F247-D322 WeakPolarHBondContact CE2-O 3.33Å; K264-D322 HydrophobicContact CB-CB 4.06Å; K264-D322 WeakPolarHBondContact CB-OD1 3.11Å; K264-D322 PolarHBondContact N-OD1 2.78Å; R304-D322 WeakPolarHBondContact CD-OD1 3.49Å; R304-D322 IonicContact CZ-OD2 3.7Å; R304-D322 IonicContact NE-OD1 3.95Å; R304-D322 PolarHBondContact NE-OD1 3.19Å; R304-D322 IonicContact NE-OD2 2.75Å; R304-D322 PolarHBondContact NE-OD2 2.98Å; R304-D322 IonicContact NH2-OD2 2.77Å; R304-D322 PolarHBondContact NH2-OD2 2.69Å; D322-T324 HydrophobicContact CB-CG2 4.31Å; D322-T324 PolarHBondContact O-N 3Å; D322-E327 HydrophobicContact CB-CG 4.29Å; D322-E327 WeakPolarHBondContact O-CB 3.34Å; D322-E327 WeakPolarHBondContact O-CG 3.5Å
323R88.9Confident93.6Very high8 Ų831.8 Ų31.83%0.0315%0.152CC..BIsolated β-bridgetrans-95.764.2178.3-74-169.273.7-158.96.4111.6F247 S261 T263 K264 A265 E266 V278 N280F247-R323 HydrophobicContact CD1-CG 4.5Å; F247-R323 HydrophobicContact CD2-CG 3.35Å; F247-R323 HydrophobicContact CE1-CG 4.42Å; F247-R323 HydrophobicContact CE2-CB 4.3Å; F247-R323 HydrophobicContact CE2-CG 3.3Å; F247-R323 HydrophobicContact CG-CG 3.95Å; F247-R323 HydrophobicContact CZ-CG 3.85Å; S261-R323 WeakPolarHBondContact OG-CD 3.04Å; S261-R323 PolarHBondContact OG-NH1 2.8Å; T263-R323 WeakPolarHBondContact OG1-CG 3.1Å; T263-R323 PolarHBondContact OG1-N 3.11Å; K264-R323 PolarHBondContact O-N 3.29Å; A265-R323 VanDerWaalsContact CA-O 3.29Å; A265-R323 WeakPolarHBondContact CA-O 3.27Å; A265-R323 HydrophobicContact CB-CB 4Å; E266-R323 PolarHBondContact N-O 3.26Å; V278-R323 VanDerWaalsContact O-CZ 3.26Å; V278-R323 PolarHBondContact O-NH1 2.84Å; V278-R323 PolarHBondContact O-NH2 3.13Å; N280-R323 PolarHBondContact OD1-NH1 3.16Å
324T89.4Confident93.7Very high34 Ų3426 Ų2621%0.20913%0.13CC..SBendtrans-120.7157.4179.366.90000110.7E266 D322 R326 E327E266-T324 HydrophobicContact CG-CG2 4.45Å; D322-T324 HydrophobicContact CB-CG2 4.31Å; D322-T324 PolarHBondContact O-N 3Å; T324-R326 PolarHBondContact O-N 2.84Å; T324-E327 WeakPolarHBondContact O-CB 3.22Å; T324-E327 PolarHBondContact O-N 2.77Å; T324-E327 WeakPolarHBondContact OG1-CG 3.47Å
325E87.4Confident93.8Very high105 Ų10525 Ų2549%0.49112%0.124SC..Hα-helixtrans-60.7-34.6179.7-73.3-58.8134.200111.6E266 E327 K328E266-E325 PolarHBondContact OE1-N 2.97Å; E325-E327 PolarHBondContact O-N 2.85Å; E325-K328 PolarHBondContact O-N 2.98Å; E325-K328 WeakPolarHBondContact OE1-CE 3.35Å; E325-K328 IonicContact OE1-NZ 3.63Å; E325-K328 PolarHBondContact OE1-NZ 2.99Å; E325-K328 WeakPolarHBondContact OE2-CE 3.49Å; E325-K328 IonicContact OE2-NZ 2.87Å; E325-K328 PolarHBondContact OE2-NZ 3.35Å
326R88.8Confident93.8Very high144 Ų14424.7 Ų24.754%0.54312%0.122SC..Hα-helixtrans-60-34.7175.8-175.7177.3177-171.6-3.4112.7S117 T324 K328 S329S117-R326 PolarHBondContact OG-NH2 2.6Å; T324-R326 PolarHBondContact O-N 2.84Å; R326-K328 VanDerWaalsContact C-N 3.31Å; R326-K328 PolarHBondContact O-N 3.39Å; R326-S329 PolarHBondContact O-N 3.44Å
327E90.2Very high93.8Very high11 Ų1124.8 Ų24.85%0.05112%0.122CC..Hα-helixtrans-74.3-19.9-174.8-73.8-77.8-159.600113.5R119 D322 T324 E325 S329 L330R119-E327 VanDerWaalsContact CD-OE1 3.25Å; R119-E327 WeakPolarHBondContact CD-OE1 3.09Å; R119-E327 IonicContact CZ-OE1 2.62Å; R119-E327 IonicContact CZ-OE2 3.05Å; R119-E327 IonicContact NE-OE1 2.68Å; R119-E327 IonicContact NH1-OE1 3.04Å; R119-E327 PolarHBondContact NH1-OE1 3.17Å; R119-E327 IonicContact NH1-OE2 3.77Å; R119-E327 PolarHBondContact NH1-OE2 2.99Å; D322-E327 HydrophobicContact CB-CG 4.29Å; D322-E327 WeakPolarHBondContact O-CB 3.34Å; D322-E327 WeakPolarHBondContact O-CG 3.5Å; T324-E327 WeakPolarHBondContact O-CB 3.22Å; T324-E327 PolarHBondContact O-N 2.77Å; T324-E327 WeakPolarHBondContact OG1-CG 3.47Å; E325-E327 PolarHBondContact O-N 2.85Å; E327-S329 PolarHBondContact O-N 3.39Å; E327-L330 PolarHBondContact O-N 3.02Å; E327-L330 VanDerWaalsContact O-N 3.09Å; E327-L330 WeakPolarHBondContact OE2-CB 3.41Å; E327-L330 WeakPolarHBondContact OE2-CD1 3.43Å
328K89.8Confident93.7Very high52 Ų5228.3 Ų28.323%0.22614%0.139CC..Hα-helixtrans-58.6-32.8172.1-62.6-177.2-175.3167.40111.9K238 A243 L244 D245 E325 R326K238-K328 PolarHBondContact NZ-O 3.05Å; A243-K328 WeakPolarHBondContact CA-O 3.26Å; L244-K328 WeakPolarHBondContact O-CA 3.27Å; D245-K328 HydrophobicContact CB-CG 4.43Å; E325-K328 PolarHBondContact O-N 2.98Å; E325-K328 WeakPolarHBondContact OE1-CE 3.35Å; E325-K328 IonicContact OE1-NZ 3.63Å; E325-K328 PolarHBondContact OE1-NZ 2.99Å; E325-K328 WeakPolarHBondContact OE2-CE 3.49Å; E325-K328 IonicContact OE2-NZ 2.87Å; E325-K328 PolarHBondContact OE2-NZ 3.35Å; R326-K328 VanDerWaalsContact C-N 3.31Å; R326-K328 PolarHBondContact O-N 3.39Å
329S91Very high93.6Very high76 Ų7629.3 Ų29.353%0.53115%0.145SC..THydrogen-bonded Turntrans-92.39-179.5-59.40000114.1S240 R326 E327S240-S329 WeakPolarHBondContact CB-O 3.43Å; R326-S329 PolarHBondContact O-N 3.44Å; E327-S329 PolarHBondContact O-N 3.39Å
330L91.8Very high93.5Very high42 Ų4231 Ų3122%0.2216%0.162CC..SBendtrans-112.6157.9177.9-65.3177.1000111.2V116 K238 E327V116-L330 HydrophobicContact CG2-CD1 4.18Å; K238-L330 PolarHBondContact NZ-O 3.42Å; E327-L330 PolarHBondContact O-N 3.02Å; E327-L330 VanDerWaalsContact O-N 3.09Å; E327-L330 WeakPolarHBondContact OE2-CB 3.41Å; E327-L330 WeakPolarHBondContact OE2-CD1 3.43Å
331D92.5Very high93.6Very high21 Ų2133.6 Ų33.611%0.11218%0.179CC..  trans-71.8140.2167.7-49.3-46.4000108.9R119 R183 K238 R239 S240R119-D331 PolarHBondContact NH2-O 3.3Å; R183-D331 IonicContact CZ-OD1 3.19Å; R183-D331 IonicContact CZ-OD2 2.66Å; R183-D331 IonicContact NE-OD1 2.78Å; R183-D331 IonicContact NE-OD2 2.72Å; R183-D331 PolarHBondContact NE-OD2 2.62Å; R183-D331 IonicContact NH2-OD1 2.71Å; R183-D331 PolarHBondContact NH2-OD1 3.25Å; R183-D331 IonicContact NH2-OD2 3.7Å; R183-D331 PolarHBondContact NH2-OD2 2.68Å; K238-D331 WeakPolarHBondContact O-CA 3.27Å; R239-D331 WeakPolarHBondContact CA-OD1 3.49Å; S240-D331 PolarHBondContact N-OD1 3.09Å; S240-D331 PolarHBondContact OG-OD1 3.21Å
332S94Very high93.8Very high1 Ų133.5 Ų33.51%0.00718%0.178CC..EExtended strand (participates in β ladder)trans-151156.4-173.864.70000110.7T237 K238 L246 N320T237-S332 WeakPolarHBondContact CA-O 3.3Å; K238-S332 WeakPolarHBondContact CE-OG 3.5Å; K238-S332 PolarHBondContact N-O 3.28Å; K238-S332 PolarHBondContact O-N 3.05Å; L246-S332 WeakPolarHBondContact CB-OG 3.04Å; N320-S332 VanDerWaalsContact OD1-CA 3.28Å; N320-S332 WeakPolarHBondContact OD1-CA 3.5Å
333S96.4Very high94Very high5 Ų533.4 Ų33.44%0.03518%0.177CC..EExtended strand (participates in β ladder)trans-147.8160178.770.40000113.2E182 I236 T319 N320E182-S333 VanDerWaalsContact CD-CB 3.41Å; E182-S333 WeakPolarHBondContact OE1-CB 3.23Å; E182-S333 PolarHBondContact OE1-OG 3.39Å; E182-S333 PolarHBondContact OE2-OG 3.49Å; E182-S333 VanDerWaalsContact OE2-OG 3.07Å; I236-S333 CarbonylContact O-C 3.59Å; I236-S333 WeakPolarHBondContact O-CA 3.33Å; I236-S333 VanDerWaalsContact O-CB 3.24Å; I236-S333 WeakPolarHBondContact O-CB 3.5Å; T319-S333 WeakPolarHBondContact CA-O 3.43Å; T319-S333 PolarHBondContact OG1-O 2.88Å; T319-S333 VanDerWaalsContact OG1-O 3.11Å; N320-S333 PolarHBondContact N-O 2.98Å; N320-S333 PolarHBondContact ND2-N 3.36Å; N320-S333 PolarHBondContact ND2-OG 2.91Å; N320-S333 VanDerWaalsContact ND2-OG 3.16Å; N320-S333 PolarHBondContact OD1-N 2.79Å; N320-S333 PolarHBondContact OD1-O 3.34Å
334A98.3Very high94.5Very high1 Ų140.1 Ų40.11%0.00821%0.207CC..EExtended strand (participates in β ladder)trans-135.6143.116800000110.3I236 I251 C317 Y318I236-A334 PolarHBondContact N-O 2.98Å; I236-A334 PolarHBondContact O-N 2.97Å; I251-A334 HydrophobicContact CD1-CB 3.5Å; I251-A334 VanDerWaalsContact CD1-CB 3.5Å; I251-A334 HydrophobicContact CG1-CB 4.37Å; C317-A334 HydrophobicContact CB-CB 4.34Å; Y318-A334 CarbonylContact O-C 3.57Å; Y318-A334 WeakPolarHBondContact O-CA 3.3Å
335V98.7Very high94.9Very high3 Ų338.7 Ų38.72%0.01820%0.199CC..EExtended strand (participates in β ladder)trans-115.9106.7171.1-177.40000107.4W134 L136 F163 V233 I234 Y235 C317 Y318W134-V335 HydrophobicContact CH2-CG2 3.48Å; W134-V335 VanDerWaalsContact CH2-CG2 3.48Å; W134-V335 HydrophobicContact CZ2-CG2 4.35Å; W134-V335 HydrophobicContact CZ3-CG1 4.22Å; W134-V335 HydrophobicContact CZ3-CG2 3.79Å; L136-V335 HydrophobicContact CD1-CB 3.89Å; L136-V335 HydrophobicContact CD1-CG1 4.38Å; L136-V335 HydrophobicContact CD1-CG2 3.57Å; F163-V335 HydrophobicContact CE1-CG1 3.99Å; V233-V335 HydrophobicContact CG1-CG1 3.44Å; V233-V335 VanDerWaalsContact CG1-CG1 3.44Å; I234-V335 WeakPolarHBondContact O-CA 3.43Å; Y235-V335 HydrophobicContact CD2-CG2 3.7Å; Y235-V335 HydrophobicContact CE2-CG2 4.12Å; Y235-V335 HydrophobicContact CG-CG2 4.25Å; C317-V335 WeakPolarHBondContact CA-O 3.14Å; Y318-V335 PolarHBondContact N-O 2.04Å; Y318-V335 PolarHBondContact O-N 3.2Å
336C98.7Very high95.4Very high1 Ų133.7 Ų33.71%0.00718%0.175CC..EExtended strand (participates in β ladder)trans-100.5145.3-175.1-59.30000111V233 I234 I315 W316 C317V233-C336 CarbonylContact C-O 3.59Å; V233-C336 VanDerWaalsContact CA-O 3.29Å; V233-C336 WeakPolarHBondContact CA-O 2.85Å; I234-C336 HydrophobicContact CB-CB 4.41Å; I234-C336 PolarHBondContact N-O 2.96Å; I234-C336 PolarHBondContact O-N 2.75Å; I315-C336 HydrophobicContact CG2-CB 3.93Å; W316-C336 CarbonylContact O-C 3.5Å; W316-C336 VanDerWaalsContact O-CA 3.25Å; W316-C336 WeakPolarHBondContact O-CA 3.07Å; C317-C336 HydrophobicContact CB-CB 4.02Å; C317-C336 WeakPolarHBondContact CB-SG 3.36Å; C317-C336 WeakPolarHBondContact SG-CB 3.35Å; C317-C336 CovalentContact SG-SG 2.04Å; C317-C336 PolarHBondContact SG-SG 3.38Å
337I98.2Very high95.7Very high1 Ų129 Ų291%0.00516%0.161CC..EExtended strand (participates in β ladder)trans-130.5128.6175.2-168.3175.6000108.8W40 F163 V231 V233 I315 W316 N339 L342W40-I337 HydrophobicContact CD2-CD1 4.23Å; W40-I337 HydrophobicContact CG-CD1 3.93Å; F163-I337 HydrophobicContact CZ-CB 4.46Å; F163-I337 HydrophobicContact CZ-CD1 4.39Å; F163-I337 HydrophobicContact CZ-CG2 4.38Å; V231-I337 HydrophobicContact CG1-CD1 3.8Å; V231-I337 HydrophobicContact CG1-CG1 3.58Å; V233-I337 HydrophobicContact CG2-CD1 4.44Å; V233-I337 HydrophobicContact CG2-CG1 4.23Å; I315-I337 WeakPolarHBondContact CA-O 3.49Å; W316-I337 HydrophobicContact CB-CG2 4.46Å; W316-I337 HydrophobicContact CE3-CG2 3.96Å; W316-I337 PolarHBondContact N-O 2.84Å; W316-I337 PolarHBondContact O-N 3.05Å; I337-N339 HydrophobicContact CD1-CB 4.37Å; I337-N339 HydrophobicContact CG1-CB 4.18Å; I337-N339 PolarHBondContact O-N 2.02Å; I337-L342 HydrophobicContact CG2-CD1 3.76Å
338E95.8Very high96Very high75 Ų7530.8 Ų30.835%0.3518%0.178SC..EExtended strand (participates in β ladder)trans-89.1101.3172.3-169170.4168.200108.8P314 I315P314-E338 HydrophobicContact CG-CG 4.12Å; P314-E338 CarbonylContact O-C 3.56Å; P314-E338 WeakPolarHBondContact O-CA 3.42Å; I315-E338 HydrophobicContact CG1-CB 4.24Å; I315-E338 HydrophobicContact CG1-CG 4.12Å
339N96.3Very high96.4Very high25 Ų2528.4 Ų28.413%0.13417%0.167CC..  trans-150.3107-173.3-171.3-87.2000111.8P314 I337 P341 L342 H343P314-N339 PolarHBondContact O-N 2.9Å; I337-N339 HydrophobicContact CD1-CB 4.37Å; I337-N339 HydrophobicContact CG1-CB 4.18Å; I337-N339 PolarHBondContact O-N 2.02Å; N339-P341 WeakPolarHBondContact OD1-CD 3.06Å; N339-L342 HydrophobicContact CB-CB 4.01Å; N339-L342 PolarHBondContact O-N 2.8Å; N339-L342 VanDerWaalsContact OD1-CB 3.29Å; N339-L342 WeakPolarHBondContact OD1-CB 3.4Å; N339-L342 PolarHBondContact OD1-N 2.92Å; N339-H343 VanDerWaalsContact O-CB 3.24Å; N339-H343 WeakPolarHBondContact O-CB 3.3Å; N339-H343 PolarHBondContact O-N 2.97Å
340G96.3Very high96.7Very high35 Ų3525.9 Ų25.936%0.36115%0.147SC..Hα-helixtrans-52.9-51.4-179.900000115H343 K344G340-H343 PolarHBondContact O-N 3.46Å; G340-K344 VanDerWaalsContact O-CB 3.31Å; G340-K344 WeakPolarHBondContact O-CB 3.34Å; G340-K344 PolarHBondContact O-N 2.97Å
341P96.4Very high96.8Very high55 Ų5529.2 Ų29.236%0.35717%0.169SC..Hα-helixtrans-59-45.7177.9-29.436.9000114.4A73 A74 N339 A345A73-P341 HydrophobicContact CB-CB 3.91Å; A74-P341 HydrophobicContact CB-CB 4.44Å; N339-P341 WeakPolarHBondContact OD1-CD 3.06Å; P341-A345 PolarHBondContact O-N 3.15Å; P341-A345 VanDerWaalsContact O-N 3.11Å
342L97.5Very high97Very high0 Ų032 Ų320%019%0.187CC..Hα-helixtrans-62.7-49.9176-174.8165.3000110.5W40 W316 I337 N339 K344 A345 F346W40-L342 HydrophobicContact CE3-CD1 4.14Å; W40-L342 HydrophobicContact CH2-CB 3.76Å; W40-L342 HydrophobicContact CH2-CD1 3.74Å; W40-L342 HydrophobicContact CH2-CG 4.09Å; W40-L342 HydrophobicContact CZ2-CB 4.18Å; W40-L342 HydrophobicContact CZ2-CD1 4.22Å; W40-L342 HydrophobicContact CZ3-CB 4.49Å; W40-L342 HydrophobicContact CZ3-CD1 3.71Å; W40-L342 HydrophobicContact CZ3-CG 4.33Å; W316-L342 HydrophobicContact CB-CD2 3.27Å; W316-L342 HydrophobicContact CD2-CD2 3.76Å; W316-L342 HydrophobicContact CE3-CD1 4.31Å; W316-L342 HydrophobicContact CE3-CD2 4.2Å; W316-L342 HydrophobicContact CG-CD2 3.35Å; I337-L342 HydrophobicContact CG2-CD1 3.76Å; N339-L342 HydrophobicContact CB-CB 4.01Å; N339-L342 PolarHBondContact O-N 2.8Å; N339-L342 VanDerWaalsContact OD1-CB 3.29Å; N339-L342 WeakPolarHBondContact OD1-CB 3.4Å; N339-L342 PolarHBondContact OD1-N 2.92Å; L342-K344 VanDerWaalsContact C-N 3.31Å; L342-K344 PolarHBondContact O-N 3.22Å; L342-A345 WeakPolarHBondContact O-CB 3.37Å; L342-A345 PolarHBondContact O-N 3.47Å; L342-F346 HydrophobicContact CD2-CD2 3.76Å; L342-F346 HydrophobicContact CD2-CE2 4Å; L342-F346 HydrophobicContact CG-CD2 4.47Å; L342-F346 PolarHBondContact O-N 2.8Å; L342-F346 VanDerWaalsContact O-N 3.12Å
343H98.2Very high97.1Very high6 Ų633 Ų333%0.02820%0.195CC..Hα-helixtrans-55.1-46.8178.7-178.6-92000111.8L307 S308 P314 N339 G340 A345 F346 L347L307-H343 HydrophobicContact CD1-CB 4.46Å; L307-H343 WeakPolarHBondContact CD1-CD2 3.46Å; S308-H343 PolarHBondContact O-CE1 2.99Å; S308-H343 PolarHBondContact O-NE2 2.79Å; S308-H343 PolarHBondContact OG-CD2 2.96Å; S308-H343 PolarHBondContact OG-NE2 3.12Å; P314-H343 VanDerWaalsContact C-CD2 3.5Å; P314-H343 VanDerWaalsContact CA-CD2 3.45Å; P314-H343 WeakPolarHBondContact CA-CD2 3.33Å; P314-H343 HydrophobicContact CB-CB 3.59Å; N339-H343 VanDerWaalsContact O-CB 3.24Å; N339-H343 WeakPolarHBondContact O-CB 3.3Å; N339-H343 PolarHBondContact O-N 2.97Å; G340-H343 PolarHBondContact O-N 3.46Å; H343-A345 VanDerWaalsContact C-N 3.3Å; H343-A345 PolarHBondContact O-N 2.89Å; H343-F346 PolarHBondContact O-N 2.72Å; H343-F346 VanDerWaalsContact O-N 3.17Å; H343-L347 VanDerWaalsContact CE1-CD1 3.49Å; H343-L347 WeakPolarHBondContact CE1-CD1 3.1Å; H343-L347 PolarHBondContact O-N 3.32Å
344K97.8Very high97Very high149 Ų14938.9 Ų38.965%0.64822%0.222SC*.Hα-helixtrans-60.4-37.7175.8-174.1-179.9178.4-175.30112.7G340 L342 F346 L347 A348G340-K344 VanDerWaalsContact O-CB 3.31Å; G340-K344 WeakPolarHBondContact O-CB 3.34Å; G340-K344 PolarHBondContact O-N 2.97Å; L342-K344 VanDerWaalsContact C-N 3.31Å; L342-K344 PolarHBondContact O-N 3.22Å; K344-F346 VanDerWaalsContact C-N 3.34Å; K344-L347 PolarHBondContact O-N 3.19Å; K344-A348 PolarHBondContact O-N 3.41Å; K344-A348 VanDerWaalsContact O-N 3.11Å
345A97.7Very high96.6Very high5 Ų541 Ų414%0.04124%0.235CC..Hα-helixtrans-66.1-36.1177.400000112.3L68 W77 P341 L342 H343 T349L68-A345 HydrophobicContact CD1-CB 3.72Å; L68-A345 HydrophobicContact CD2-CB 3.84Å; L68-A345 HydrophobicContact CG-CB 4.45Å; W77-A345 PolarHBondContact NE1-O 2.93Å; P341-A345 PolarHBondContact O-N 3.15Å; P341-A345 VanDerWaalsContact O-N 3.11Å; L342-A345 WeakPolarHBondContact O-CB 3.37Å; L342-A345 PolarHBondContact O-N 3.47Å; H343-A345 VanDerWaalsContact C-N 3.3Å; H343-A345 PolarHBondContact O-N 2.89Å; A345-T349 PolarHBondContact O-N 2.66Å; A345-T349 PolarHBondContact O-OG1 3.35Å
346F98Very high96.1Very high0 Ų043.4 Ų43.40%025%0.247CC..Hα-helixtrans-76.9-36174.4-86.5-97.1000113L42 L68 W77 W305 L307 W316 L342 H343 K344 A348 T349 E350L42-F346 HydrophobicContact CD1-CE2 3.68Å; L42-F346 HydrophobicContact CD1-CZ 3.68Å; L42-F346 HydrophobicContact CD2-CZ 4.35Å; L68-F346 HydrophobicContact CD1-CD2 4.28Å; L68-F346 HydrophobicContact CD1-CE2 3.97Å; W77-F346 AromaticContact CH2-CE2 3.84Å; W77-F346 HydrophobicContact CH2-CE2 3.84Å; W77-F346 AromaticContact CH2-CZ 3.73Å; W77-F346 HydrophobicContact CH2-CZ 3.73Å; W77-F346 AromaticContact CZ2-CD2 3.97Å; W77-F346 HydrophobicContact CZ2-CD2 3.97Å; W77-F346 HydrophobicContact CZ2-CE1 4.03Å; W77-F346 AromaticContact CZ2-CE2 3.43Å; W77-F346 HydrophobicContact CZ2-CE2 3.43Å; W77-F346 VanDerWaalsContact CZ2-CE2 3.43Å; W77-F346 HydrophobicContact CZ2-CG 4.48Å; W77-F346 AromaticContact CZ2-CZ 3.47Å; W77-F346 HydrophobicContact CZ2-CZ 3.47Å; W77-F346 VanDerWaalsContact CZ2-CZ 3.47Å; W305-F346 HydrophobicContact CD2-CD1 4.02Å; W305-F346 AromaticContact CD2-CE1 3.8Å; W305-F346 HydrophobicContact CD2-CE1 3.8Å; W305-F346 AromaticContact CE2-CD1 3.93Å; W305-F346 AromaticContact CE2-CE1 3.67Å; W305-F346 HydrophobicContact CE3-CD1 4.02Å; W305-F346 HydrophobicContact CE3-CE1 4.25Å; W305-F346 HydrophobicContact CG-CE1 4.19Å; W305-F346 AromaticContact CH2-CD1 3.92Å; W305-F346 HydrophobicContact CH2-CD1 3.92Å; W305-F346 HydrophobicContact CH2-CE1 4.49Å; W305-F346 AromaticContact CZ2-CD1 3.87Å; W305-F346 HydrophobicContact CZ2-CD1 3.87Å; W305-F346 HydrophobicContact CZ2-CE1 4.02Å; W305-F346 AromaticContact CZ3-CD1 4Å; W305-F346 HydrophobicContact CZ3-CD1 4Å; W305-F346 AromaticContact NE1-CE1 3.94Å; L307-F346 HydrophobicContact CD1-CB 3.66Å; L307-F346 HydrophobicContact CD2-CB 3.85Å; L307-F346 HydrophobicContact CG-CB 4.33Å; W316-F346 AromaticContact CD1-CD1 3.81Å; W316-F346 AromaticContact CD1-CD2 3.81Å; W316-F346 AromaticContact CD1-CE1 4Å; W316-F346 AromaticContact CD1-CE2 3.99Å; W316-F346 AromaticContact CD1-CG 3.71Å; W316-F346 AromaticContact CE2-CE2 3.92Å; W316-F346 AromaticContact CE2-CZ 3.64Å; W316-F346 HydrophobicContact CG-CD2 4.47Å; W316-F346 HydrophobicContact CZ2-CE1 4.39Å; W316-F346 HydrophobicContact CZ2-CE2 4.4Å; W316-F346 AromaticContact CZ2-CZ 3.86Å; W316-F346 HydrophobicContact CZ2-CZ 3.86Å; W316-F346 AromaticContact NE1-CD1 3.47Å; W316-F346 AromaticContact NE1-CD2 3.82Å; W316-F346 AromaticContact NE1-CE1 3.19Å; W316-F346 AromaticContact NE1-CE2 3.55Å; W316-F346 AromaticContact NE1-CG 3.77Å; W316-F346 AromaticContact NE1-CZ 3.23Å; L342-F346 HydrophobicContact CD2-CD2 3.76Å; L342-F346 HydrophobicContact CD2-CE2 4Å; L342-F346 HydrophobicContact CG-CD2 4.47Å; L342-F346 PolarHBondContact O-N 2.8Å; L342-F346 VanDerWaalsContact O-N 3.12Å; H343-F346 PolarHBondContact O-N 2.72Å; H343-F346 VanDerWaalsContact O-N 3.17Å; K344-F346 VanDerWaalsContact C-N 3.34Å; F346-A348 PolarHBondContact O-N 2.86Å; F346-T349 WeakPolarHBondContact O-CA 3.29Å; F346-T349 VanDerWaalsContact O-CB 3.23Å; F346-T349 WeakPolarHBondContact O-CB 3.43Å; F346-T349 PolarHBondContact O-N 2.72Å; F346-E350 PolarHBondContact O-N 3.28Å
347L97.1Very high94.9Very high45 Ų4547.5 Ų47.524%0.23628%0.281CS..Hα-helixtrans-57.1-37.1170.7-75.3178.3000111.6L307 K311 H343 K344 T349 E350L307-L347 HydrophobicContact CD2-CB 4.47Å; L307-L347 HydrophobicContact CD2-CD2 3.65Å; L307-L347 HydrophobicContact CD2-CG 3.94Å; K311-L347 HydrophobicContact CG-CD1 4.2Å; H343-L347 VanDerWaalsContact CE1-CD1 3.49Å; H343-L347 WeakPolarHBondContact CE1-CD1 3.1Å; H343-L347 PolarHBondContact O-N 3.32Å; K344-L347 PolarHBondContact O-N 3.19Å; L347-T349 VanDerWaalsContact C-N 3.28Å; L347-T349 PolarHBondContact O-N 3.33Å; L347-E350 PolarHBondContact O-N 2.86Å
348A96.5Very high93.5Very high49 Ų4951.6 Ų51.641%0.40531%0.309SS..Hα-helixtrans-65.4-32.4175.300000112.4K344 F346 E350 V351K344-A348 PolarHBondContact O-N 3.41Å; K344-A348 VanDerWaalsContact O-N 3.11Å; F346-A348 PolarHBondContact O-N 2.86Å; A348-E350 PolarHBondContact O-N 3.21Å; A348-V351 WeakPolarHBondContact O-CG2 3.35Å
349T97.4Very high93.4Very high2 Ų250.4 Ų50.41%0.01231%0.307CS..Hα-helixtrans-66.7-27.1174.4-550000112.4W77 L285 H286 L287 L296 A345 F346 L347W77-T349 PolarHBondContact NE1-OG1 2.67Å; W77-T349 VanDerWaalsContact NE1-OG1 3.14Å; L285-T349 WeakPolarHBondContact CA-O 3.06Å; L285-T349 HydrophobicContact CB-CG2 4.12Å; L285-T349 HydrophobicContact CD2-CG2 3.97Å; L285-T349 WeakPolarHBondContact CD2-O 3.47Å; L285-T349 HydrophobicContact CG-CG2 4.47Å; H286-T349 PolarHBondContact N-O 2.94Å; H286-T349 VanDerWaalsContact O-CA 3.23Å; H286-T349 WeakPolarHBondContact O-CA 3.15Å; H286-T349 VanDerWaalsContact O-CG2 3.25Å; H286-T349 WeakPolarHBondContact O-CG2 3.43Å; L287-T349 HydrophobicContact CD2-CG2 3.8Å; L287-T349 WeakPolarHBondContact CD2-OG1 3.45Å; L296-T349 HydrophobicContact CD1-CG2 4.2Å; A345-T349 PolarHBondContact O-N 2.66Å; A345-T349 PolarHBondContact O-OG1 3.35Å; F346-T349 WeakPolarHBondContact O-CA 3.29Å; F346-T349 VanDerWaalsContact O-CB 3.23Å; F346-T349 WeakPolarHBondContact O-CB 3.43Å; F346-T349 PolarHBondContact O-N 2.72Å; L347-T349 VanDerWaalsContact C-N 3.28Å; L347-T349 PolarHBondContact O-N 3.33Å
350E96.3Very high93.2Very high22 Ų2251.7 Ų51.710%0.10332%0.316CS..THydrogen-bonded Turntrans-91.8-0-176-73176.6-159.700114.8I281 L285 W305 L307 F346 L347 A348 T352 A353I281-E350 HydrophobicContact CD1-CG 4.06Å; I281-E350 WeakPolarHBondContact CD1-OE1 3.46Å; L285-E350 HydrophobicContact CD2-CB 4.29Å; L285-E350 HydrophobicContact CD2-CG 3.55Å; W305-E350 HydrophobicContact CH2-CG 4.31Å; W305-E350 WeakPolarHBondContact CH2-OE1 3.41Å; W305-E350 WeakPolarHBondContact CZ3-OE1 3.41Å; L307-E350 WeakPolarHBondContact CB-OE1 3.37Å; L307-E350 VanDerWaalsContact CD2-CD 3.5Å; L307-E350 WeakPolarHBondContact CD2-OE1 3.48Å; F346-E350 PolarHBondContact O-N 3.28Å; L347-E350 PolarHBondContact O-N 2.86Å; A348-E350 PolarHBondContact O-N 3.21Å; E350-T352 PolarHBondContact O-N 3.11Å; E350-T352 VanDerWaalsContact O-N 3.1Å; E350-A353 HydrophobicContact CB-CB 4.19Å; E350-A353 HydrophobicContact CG-CB 4.48Å; E350-A353 WeakPolarHBondContact O-CB 3.36Å; E350-A353 PolarHBondContact O-N 3.1Å
351V94.9Very high93.1Very high112 Ų11252.7 Ų52.768%0.67931%0.314SS*.THydrogen-bonded Turntrans-57.2-34.5-172171.30000113.5A348A348-V351 WeakPolarHBondContact O-CG2 3.35Å
352T95.5Very high92.9Very high79 Ų7952.5 Ų52.549%0.48531%0.311SS..THydrogen-bonded Turntrans-108.312.4177.957.60000112.5G284 H286 E350G284-T352 CarbonylContact O-C 3.58Å; G284-T352 PolarHBondContact O-OG1 3.05Å; H286-T352 PolarHBondContact CE1-OG1 3.11Å; H286-T352 PolarHBondContact ND1-OG1 3.02Å; E350-T352 PolarHBondContact O-N 3.11Å; E350-T352 VanDerWaalsContact O-N 3.1Å
353A96.1Very high92.6Very high22 Ų2255.8 Ų55.818%0.18233%0.331CS..  trans-70.1138-17600000111.4I281 S283 L285 E350 V355I281-A353 HydrophobicContact CG2-CB 4.08Å; S283-A353 CarbonylContact O-C 3.51Å; S283-A353 VanDerWaalsContact O-CA 3.25Å; S283-A353 WeakPolarHBondContact O-CA 3.4Å; L285-A353 HydrophobicContact CD2-CB 3.97Å; E350-A353 HydrophobicContact CB-CB 4.19Å; E350-A353 HydrophobicContact CG-CB 4.48Å; E350-A353 WeakPolarHBondContact O-CB 3.36Å; E350-A353 PolarHBondContact O-N 3.1Å; A353-V355 HydrophobicContact CB-CG2 4.26Å
354Q94.3Very high92.2Very high130 Ų13059.1 Ų59.161%0.60735%0.351SS*.EExtended strand (participates in β ladder)trans-88.9109.7165.1-63.4-17815.800107.5M282 S283M282-Q354 WeakPolarHBondContact CB-O 3.16Å; M282-Q354 PolarHBondContact N-O 3.3Å; S283-Q354 PolarHBondContact O-N 2.95Å
355V91.7Very high91.8Very high46 Ų4652.7 Ų52.728%0.27933%0.33SS..EExtended strand (participates in β ladder)trans-102.4134.4177.6-177.10000108R279 N280 I281 A353 A357R279-V355 HydrophobicContact CB-CG1 3.42Å; R279-V355 VanDerWaalsContact CB-CG1 3.42Å; R279-V355 HydrophobicContact CG-CG1 4.18Å; N280-V355 WeakPolarHBondContact O-CA 3.48Å; I281-V355 HydrophobicContact CG1-CG2 4.17Å; A353-V355 HydrophobicContact CB-CG2 4.26Å; V355-A357 PolarHBondContact O-N 3.19Å
356D86.3Confident91.4Very high52 Ų5256.4 Ų56.428%0.27835%0.352SS..  trans-56.3138.7179.5-163.39.1000110.7N280 M282 C358N280-D356 HydrophobicContact CB-CB 4.35Å; N280-D356 PolarHBondContact O-N 2.71Å; M282-D356 HydrophobicContact CG-CB 4.26Å; M282-D356 HydrophobicContact SD-CB 4.46Å; D356-C358 PolarHBondContact O-N 3.23Å; D356-C358 VanDerWaalsContact O-N 3.1Å
357A75.2Confident90.8Very high87 Ų8761.1 Ų61.172%0.71938%0.381SS*.  trans-78.198175.100000107.5V355V355-A357 PolarHBondContact O-N 3.19Å
358C68.4Low90.2Very high87 Ų8762.5 Ų62.559%0.58839%0.394SS*.  trans-57.10144.2-64.80000108.7C271 R279 D356C271-C358 HydrophobicContact CB-CB 3.12Å; C271-C358 WeakPolarHBondContact CB-SG 3.22Å; C271-C358 VanDerWaalsContact SG-CA 3.52Å; C271-C358 WeakPolarHBondContact SG-CB 3.21Å; C271-C358 CovalentContact SG-SG 2.02Å; C271-C358 PolarHBondContact SG-SG 2.78Å; R279-C358 HydrophobicContact CG-CB 4.38Å; R279-C358 WeakPolarHBondContact CG-SG 3.45Å; D356-C358 PolarHBondContact O-N 3.23Å; D356-C358 VanDerWaalsContact O-N 3.1Å

Retrieved 358 of 358 residues in 220.7 ms (Link to these results)