A0A077YZN7_TRITR Loading...

GPI mannosyltransferase 2

Mannosyltransferase involved in glycosylphosphatidylinositol-anchor biosynthesis.

AlphaFold DB , UniProt , Accession A0A077YZN7, Species TRITR (Trichuris trichiura, Whipworm), Gene n/a, Length 452 aa.

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(Predicted Aligned Error values between residue pairs)

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Site	Residue	pLDDT	pLDDT confidence	pLDDT₁₀	pLDDT10 confidence	SASA	SASA [Å²]	SASA₁₀	SASA10 [Å²]	RSA	RSA unformatted	RSA₁₀	RSA10 unformatted	Surface	Surface10 (not used)	Disorder (not used)	Disorder	Sec. str.	Secondary structure	Isomer	Phi (φ)	Psi (ψ)	Omega (ω)	Chi 1 (χ₁)	Chi 2 (χ₂)	Chi 3 (χ₃)	Chi 4 (χ₄)	Chi 5 (χ₅)	Tau (τ)	Contacts (colored by PAE)	Contact details
1	M	39.7	Very low	41.5	Very low	218 Å²	218	136.5 Å²	136.5	100%	1.074	67%	0.665	S	S	*	*				0	-0	0	-73.8	-178.9	175.9	0	0	117.8
2	P	45.9	Very low	42.3	Very low	104 Å²	104	128.4 Å²	128.4	68%	0.675	63%	0.625	S	S	*	*	H	α-helix	trans	-78.6	-21.3	-177.1	29.9	-32.5	0	0	0	115.1	Y6	P2-Y6 PolarHBondContact O-N 3.44Å
3	V	40.7	Very low	43.1	Very low	106 Å²	106	119.4 Å²	119.4	64%	0.642	59%	0.585	S	S	*	*	H	α-helix	trans	-70.3	-39.5	-176.2	-177.4	0	0	0	0	112.2	A5 Y6 V7	V3-A5 PolarHBondContact O-N 2.76Å; V3-Y6 PolarHBondContact O-N 2.92Å; V3-V7 HydrophobicContact CG1-CG2 4.28Å; V3-V7 WeakPolarHBondContact O-CG2 3.49Å; V3-V7 PolarHBondContact O-N 2.74Å
4	K	34.7	Very low	44.2	Very low	187 Å²	187	117.7 Å²	117.7	81%	0.813	59%	0.585	S	S	*	*	H	α-helix	trans	-66.6	-35.9	178	-74.1	-170.9	175.8	-178.3	0	112.7	Y6 K8	K4-Y6 VanDerWaalsContact C-N 3.35Å; K4-K8 WeakPolarHBondContact O-CB 3.49Å; K4-K8 PolarHBondContact O-N 3.38Å; K4-K8 VanDerWaalsContact O-N 3.11Å
5	A	39.3	Very low	45.7	Very low	60 Å²	60	113.3 Å²	113.3	50%	0.496	57%	0.567	S	S	.	*	H	α-helix	trans	-69.9	-31.7	175	0	0	0	0	0	112.6	V3 K9	V3-A5 PolarHBondContact O-N 2.76Å; A5-K9 WeakPolarHBondContact O-CG 3.23Å; A5-K9 PolarHBondContact O-N 2.85Å
6	Y	35.5	Very low	47.8	Very low	131 Å²	131	106.3 Å²	106.3	51%	0.514	53%	0.532	S	S	.	.	H	α-helix	trans	-78.3	-36	178.1	-161.8	-97	0	0	0	112.9	P2 V3 K4 R10 K178	P2-Y6 PolarHBondContact O-N 3.44Å; V3-Y6 PolarHBondContact O-N 2.92Å; K4-Y6 VanDerWaalsContact C-N 3.35Å; Y6-R10 PolarHBondContact O-N 3.49Å; Y6-K178 PolarHBondContact OH-NZ 3.45Å
7	V	39.3	Very low	49.8	Very low	84 Å²	84	103.4 Å²	103.4	51%	0.509	52%	0.518	S	S	.	.	H	α-helix	trans	-68.9	-42.2	174.8	173.9	0	0	0	0	111.2	V3 K9 R10	V3-V7 HydrophobicContact CG1-CG2 4.28Å; V3-V7 WeakPolarHBondContact O-CG2 3.49Å; V3-V7 PolarHBondContact O-N 2.74Å; V7-K9 VanDerWaalsContact C-N 3.33Å; V7-K9 PolarHBondContact O-N 3.43Å; V7-R10 PolarHBondContact O-N 3.29Å; V7-R10 VanDerWaalsContact O-N 3.11Å
8	K	42.4	Very low	51.9	Low	145 Å²	145	100 Å²	100	63%	0.63	51%	0.505	S	S	*	.	H	α-helix	trans	-59	-42.8	176.1	-159.7	174.5	-175.8	-178.3	0	111.9	K4 R10 Q11	K4-K8 WeakPolarHBondContact O-CB 3.49Å; K4-K8 PolarHBondContact O-N 3.38Å; K4-K8 VanDerWaalsContact O-N 3.11Å; K8-R10 VanDerWaalsContact C-N 3.3Å; K8-R10 PolarHBondContact O-N 3.14Å; K8-Q11 PolarHBondContact O-N 2.77Å
9	K	44.3	Very low	53.9	Low	132 Å²	132	94.7 Å²	94.7	57%	0.574	48%	0.478	S	S	*	.	H	α-helix	trans	-66.7	-21.9	176.2	-81.3	180	171.2	-179.9	0	115.3	A5 V7	A5-K9 WeakPolarHBondContact O-CG 3.23Å; A5-K9 PolarHBondContact O-N 2.85Å; V7-K9 VanDerWaalsContact C-N 3.33Å; V7-K9 PolarHBondContact O-N 3.43Å
10	R	45.6	Very low	55.7	Low	200 Å²	200	90 Å²	90	76%	0.755	45%	0.454	S	S	*	.	H	α-helix	trans	-80.2	-26.8	179	-135.3	-177.2	-168.2	-173.8	2.9	112.1	Y6 V7 K8	Y6-R10 PolarHBondContact O-N 3.49Å; V7-R10 PolarHBondContact O-N 3.29Å; V7-R10 VanDerWaalsContact O-N 3.11Å; K8-R10 VanDerWaalsContact C-N 3.3Å; K8-R10 PolarHBondContact O-N 3.14Å
11	Q	49.3	Very low	57.2	Low	135 Å²	135	90 Å²	90	63%	0.631	46%	0.455	S	S	*	.	H	α-helix	trans	-77.3	-25	175.1	-79.7	177.9	-37.7	0	0	112.9	K8 G13 V14 T15	K8-Q11 PolarHBondContact O-N 2.77Å; Q11-G13 PolarHBondContact O-N 3.09Å; Q11-V14 WeakPolarHBondContact O-CB 3.01Å; Q11-V14 PolarHBondContact O-N 3.18Å; Q11-T15 PolarHBondContact O-N 2.86Å
12	E	50.4	Low	59.7	Low	39 Å²	39	82.1 Å²	82.1	18%	0.182	42%	0.416	C	S	.	.	H	α-helix	trans	-67.5	-30.1	-173.5	-72.6	164.3	-171.2	0	0	113.7	V14 T15 Y126	E12-V14 VanDerWaalsContact C-N 3.25Å; E12-V14 PolarHBondContact O-N 2.92Å; E12-T15 PolarHBondContact O-N 2.93Å; E12-T15 PolarHBondContact O-OG1 3.2Å; E12-Y126 HydrophobicContact CB-CE1 4.02Å
13	G	52.8	Low	61.9	Low	11 Å²	11	77.4 Å²	77.4	11%	0.113	39%	0.385	C	S	.	.	H	α-helix	trans	-68.4	-24.6	172.4	0	0	0	0	0	113.6	Q11 T15	Q11-G13 PolarHBondContact O-N 3.09Å; G13-T15 VanDerWaalsContact C-N 3.3Å
14	V	58.4	Low	64.2	Low	96 Å²	96	72.5 Å²	72.5	58%	0.582	36%	0.356	S	S	*	.	H	α-helix	trans	-75.6	-23.9	177.9	-174.3	0	0	0	0	110.7	Q11 E12 A16 L17	Q11-V14 WeakPolarHBondContact O-CB 3.01Å; Q11-V14 PolarHBondContact O-N 3.18Å; E12-V14 VanDerWaalsContact C-N 3.25Å; E12-V14 PolarHBondContact O-N 2.92Å; V14-A16 VanDerWaalsContact C-N 3.26Å; V14-A16 PolarHBondContact O-N 3Å; V14-L17 WeakPolarHBondContact O-CB 3.43Å; V14-L17 PolarHBondContact O-N 3.43Å
15	T	67.7	Low	66.9	Low	52 Å²	52	69.9 Å²	69.9	32%	0.319	35%	0.345	S	S	.	.	H	α-helix	trans	-69.8	-24.6	-179.6	69.1	0	0	0	0	112.6	Q11 E12 G13 P18 N410	Q11-T15 PolarHBondContact O-N 2.86Å; E12-T15 PolarHBondContact O-N 2.93Å; E12-T15 PolarHBondContact O-OG1 3.2Å; G13-T15 VanDerWaalsContact C-N 3.3Å; T15-P18 WeakPolarHBondContact O-CD 3Å; T15-N410 PolarHBondContact O-OD1 2.66Å
16	A	78.2	Confident	69.4	Low	0 Å²	0	69.7 Å²	69.7	0%	0	34%	0.337	C	S	.	.	T	Hydrogen-bonded Turn	trans	-85.3	-13.4	177.5	0	0	0	0	0	113.8	V14 P18 L19 L20 V143	V14-A16 VanDerWaalsContact C-N 3.26Å; V14-A16 PolarHBondContact O-N 3Å; A16-P18 VanDerWaalsContact C-CD 3.46Å; A16-L19 WeakPolarHBondContact O-CB 3.25Å; A16-L19 PolarHBondContact O-N 3.41Å; A16-L20 PolarHBondContact O-N 3.22Å; A16-V143 HydrophobicContact CB-CG1 4.06Å
17	L	82.6	Confident	72.1	Confident	57 Å²	57	63.6 Å²	63.6	30%	0.298	31%	0.314	S	S	.	.	H	α-helix	trans	-55.1	-42.9	-178	-178.6	64.9	0	0	0	113.7	V14 L19 L20 L21 Y119	V14-L17 WeakPolarHBondContact O-CB 3.43Å; V14-L17 PolarHBondContact O-N 3.43Å; L17-L19 PolarHBondContact O-N 3.28Å; L17-L20 PolarHBondContact O-N 3.03Å; L17-L21 HydrophobicContact CD1-CD1 4.32Å; L17-L21 HydrophobicContact CD1-CG 4.23Å; L17-L21 HydrophobicContact CG-CD1 4.1Å; L17-L21 HydrophobicContact CG-CG 4.43Å; L17-L21 WeakPolarHBondContact O-CG 3.35Å; L17-L21 PolarHBondContact O-N 3.42Å; L17-L21 VanDerWaalsContact O-N 3.08Å; L17-Y119 HydrophobicContact CD1-CD2 4.25Å; L17-Y119 HydrophobicContact CD1-CG 4.46Å
18	P	88	Confident	74.6	Confident	43 Å²	43	62.6 Å²	62.6	28%	0.279	30%	0.301	S	S	.	.	H	α-helix	trans	-59.5	-33.9	176.9	-24.4	35.5	0	0	0	113.3	T15 A16 Q22 N410	T15-P18 WeakPolarHBondContact O-CD 3Å; A16-P18 VanDerWaalsContact C-CD 3.46Å; P18-Q22 WeakPolarHBondContact O-CB 3.5Å; P18-Q22 VanDerWaalsContact O-CD 3.31Å; P18-Q22 WeakPolarHBondContact O-CG 3.31Å; P18-Q22 PolarHBondContact O-N 3.18Å; P18-Q22 VanDerWaalsContact O-N 3.09Å; P18-Q22 PolarHBondContact O-NE2 3.48Å; P18-N410 HydrophobicContact CB-CB 4.21Å; P18-N410 HydrophobicContact CG-CB 4.34Å
19	L	90.3	Very high	77.1	Confident	0 Å²	0	59.7 Å²	59.7	0%	0	29%	0.292	C	S	.	.	H	α-helix	trans	-69.6	-41.9	179.9	-63	168.2	0	0	0	111.2	A16 L17 Q22 S23 R140 V144 L412	A16-L19 WeakPolarHBondContact O-CB 3.25Å; A16-L19 PolarHBondContact O-N 3.41Å; L17-L19 PolarHBondContact O-N 3.28Å; L19-Q22 PolarHBondContact O-N 3.38Å; L19-S23 PolarHBondContact O-N 3.02Å; L19-R140 HydrophobicContact CD1-CG 4.45Å; L19-V144 HydrophobicContact CD1-CG2 3.77Å; L19-L412 HydrophobicContact CD2-CB 4.15Å
20	L	89	Confident	79.6	Confident	0 Å²	0	55.2 Å²	55.2	0%	0	27%	0.274	C	S	.	.	H	α-helix	trans	-66.2	-45.2	179.1	-65.1	164	0	0	0	111.3	A16 L17 Q22 S23 C24 Y119 V143	A16-L20 PolarHBondContact O-N 3.22Å; L17-L20 PolarHBondContact O-N 3.03Å; L20-Q22 VanDerWaalsContact C-N 3.3Å; L20-Q22 PolarHBondContact O-N 3.2Å; L20-S23 VanDerWaalsContact O-CB 3.28Å; L20-S23 WeakPolarHBondContact O-CB 3.32Å; L20-S23 PolarHBondContact O-N 3.16Å; L20-S23 VanDerWaalsContact O-N 3.16Å; L20-C24 PolarHBondContact O-N 2.56Å; L20-C24 PolarHBondContact O-SG 3.43Å; L20-Y119 WeakPolarHBondContact CD1-O 3.47Å; L20-V143 HydrophobicContact CD1-CG1 4.48Å; L20-V143 HydrophobicContact CD2-CG1 3.91Å; L20-V143 HydrophobicContact CG-CG1 4.14Å
21	L	88.1	Confident	81.9	Confident	90 Å²	90	45.7 Å²	45.7	47%	0.471	24%	0.238	S	C	.	.	H	α-helix	trans	-62.8	-38.2	175.8	-66.5	175.2	0	0	0	112.2	L17 C24 F25	L17-L21 HydrophobicContact CD1-CD1 4.32Å; L17-L21 HydrophobicContact CD1-CG 4.23Å; L17-L21 HydrophobicContact CG-CD1 4.1Å; L17-L21 HydrophobicContact CG-CG 4.43Å; L17-L21 WeakPolarHBondContact O-CG 3.35Å; L17-L21 PolarHBondContact O-N 3.42Å; L17-L21 VanDerWaalsContact O-N 3.08Å; L21-C24 PolarHBondContact O-N 2.61Å; L21-F25 PolarHBondContact O-N 3.33Å
22	Q	91.5	Very high	84.1	Confident	53 Å²	53	42.3 Å²	42.3	25%	0.248	22%	0.221	C	C	.	.	H	α-helix	trans	-65.4	-39.3	174.5	-75	167.5	40	0	0	111.9	P18 L19 L20 F25 V26 N410 N411 L412	P18-Q22 WeakPolarHBondContact O-CB 3.5Å; P18-Q22 VanDerWaalsContact O-CD 3.31Å; P18-Q22 WeakPolarHBondContact O-CG 3.31Å; P18-Q22 PolarHBondContact O-N 3.18Å; P18-Q22 VanDerWaalsContact O-N 3.09Å; P18-Q22 PolarHBondContact O-NE2 3.48Å; L19-Q22 PolarHBondContact O-N 3.38Å; L20-Q22 VanDerWaalsContact C-N 3.3Å; L20-Q22 PolarHBondContact O-N 3.2Å; Q22-F25 PolarHBondContact O-N 3.47Å; Q22-V26 WeakPolarHBondContact O-CB 3.35Å; Q22-V26 VanDerWaalsContact O-CG2 3.25Å; Q22-V26 WeakPolarHBondContact O-CG2 3.44Å; Q22-V26 PolarHBondContact O-N 2.96Å; Q22-N410 PolarHBondContact NE2-O 2.85Å; Q22-N411 VanDerWaalsContact OE1-CA 3.28Å; Q22-L412 HydrophobicContact CB-CB 4.19Å
23	S	91.9	Very high	86.3	Confident	4 Å²	4	43.6 Å²	43.6	3%	0.028	23%	0.229	C	C	.	.	H	α-helix	trans	-56.7	-50.5	173.7	-174	0	0	0	0	111.2	L19 L20 F25 V26 A27 C147	L19-S23 PolarHBondContact O-N 3.02Å; L20-S23 VanDerWaalsContact O-CB 3.28Å; L20-S23 WeakPolarHBondContact O-CB 3.32Å; L20-S23 PolarHBondContact O-N 3.16Å; L20-S23 VanDerWaalsContact O-N 3.16Å; S23-F25 PolarHBondContact O-N 3.32Å; S23-V26 PolarHBondContact O-N 3.37Å; S23-A27 WeakPolarHBondContact O-CB 3.4Å; S23-A27 PolarHBondContact O-N 3.42Å; S23-C147 WeakPolarHBondContact OG-CA 3.37Å; S23-C147 PolarHBondContact OG-O 3.05Å; S23-C147 VanDerWaalsContact OG-O 3.11Å
24	C	89.1	Confident	88.5	Confident	4 Å²	4	45.1 Å²	45.1	3%	0.027	23%	0.232	C	C	.	.	H	α-helix	trans	-56.6	-50.6	177.1	-64.7	0	0	0	0	111.6	L20 L21 V26 A27 W28	L20-C24 PolarHBondContact O-N 2.56Å; L20-C24 PolarHBondContact O-SG 3.43Å; L21-C24 PolarHBondContact O-N 2.61Å; C24-V26 PolarHBondContact O-N 3.28Å; C24-A27 PolarHBondContact O-N 3.1Å; C24-W28 WeakPolarHBondContact O-CB 3.42Å; C24-W28 PolarHBondContact O-N 2.83Å
25	F	90.4	Very high	90.2	Very high	132 Å²	132	41.5 Å²	41.5	58%	0.579	21%	0.21	S	C	*	.	H	α-helix	trans	-62.7	-42.1	-178.6	-177.3	-96.7	0	0	0	112.5	L21 Q22 S23 W28 L29	L21-F25 PolarHBondContact O-N 3.33Å; Q22-F25 PolarHBondContact O-N 3.47Å; S23-F25 PolarHBondContact O-N 3.32Å; F25-W28 PolarHBondContact O-N 3.5Å; F25-L29 WeakPolarHBondContact O-CB 3.36Å; F25-L29 PolarHBondContact O-N 3.35Å
26	V	92.9	Very high	91.6	Very high	56 Å²	56	43.1 Å²	43.1	34%	0.339	21%	0.213	S	C	.	.	H	α-helix	trans	-64.7	-44.7	176.9	169.9	0	0	0	0	110.6	Q22 S23 C24 W28 L29 L30	Q22-V26 WeakPolarHBondContact O-CB 3.35Å; Q22-V26 VanDerWaalsContact O-CG2 3.25Å; Q22-V26 WeakPolarHBondContact O-CG2 3.44Å; Q22-V26 PolarHBondContact O-N 2.96Å; S23-V26 PolarHBondContact O-N 3.37Å; C24-V26 PolarHBondContact O-N 3.28Å; V26-W28 VanDerWaalsContact C-N 3.33Å; V26-W28 PolarHBondContact O-N 2.98Å; V26-L29 PolarHBondContact O-N 2.9Å; V26-L30 HydrophobicContact CG1-CD1 3.92Å; V26-L30 HydrophobicContact CG1-CG 4.31Å; V26-L30 WeakPolarHBondContact O-CB 3.31Å; V26-L30 VanDerWaalsContact O-CG 3.31Å; V26-L30 WeakPolarHBondContact O-CG 3.27Å; V26-L30 PolarHBondContact O-N 3.5Å
27	A	92.8	Very high	92.5	Very high	3 Å²	3	49.1 Å²	49.1	3%	0.025	24%	0.244	C	C	.	.	H	α-helix	trans	-60.1	-45.2	178.2	0	0	0	0	0	111.1	S23 C24 L30 Q31 Y68 T152 H156 I442	S23-A27 WeakPolarHBondContact O-CB 3.4Å; S23-A27 PolarHBondContact O-N 3.42Å; C24-A27 PolarHBondContact O-N 3.1Å; A27-L30 PolarHBondContact O-N 3.34Å; A27-Q31 WeakPolarHBondContact O-CB 3.43Å; A27-Q31 PolarHBondContact O-N 2.59Å; A27-Y68 PolarHBondContact O-OH 3.32Å; A27-T152 HydrophobicContact CB-CG2 4.42Å; A27-H156 HydrophobicContact CB-CB 4.29Å; A27-I442 HydrophobicContact CB-CD1 3.98Å
28	W	91.2	Very high	93.1	Very high	63 Å²	63	49.8 Å²	49.8	24%	0.239	25%	0.248	C	C	.	.	H	α-helix	trans	-59	-47.3	175.1	-68.5	-2.1	0	0	0	113.3	C24 F25 V26 L30 Q31 F32 F65 Y68 Q115	C24-W28 WeakPolarHBondContact O-CB 3.42Å; C24-W28 PolarHBondContact O-N 2.83Å; F25-W28 PolarHBondContact O-N 3.5Å; V26-W28 VanDerWaalsContact C-N 3.33Å; V26-W28 PolarHBondContact O-N 2.98Å; W28-L30 VanDerWaalsContact C-N 3.34Å; W28-L30 PolarHBondContact O-N 3.35Å; W28-Q31 PolarHBondContact O-N 3.28Å; W28-Q31 PolarHBondContact O-OE1 2.79Å; W28-F32 VanDerWaalsContact O-CB 3.3Å; W28-F32 WeakPolarHBondContact O-CB 3.42Å; W28-F32 PolarHBondContact O-N 3.08Å; W28-F65 HydrophobicContact CB-CE1 4.44Å; W28-F65 AromaticContact CD2-CE1 3.88Å; W28-F65 HydrophobicContact CD2-CE1 3.88Å; W28-F65 HydrophobicContact CD2-CZ 4.34Å; W28-F65 AromaticContact CE2-CE1 3.84Å; W28-F65 HydrophobicContact CE3-CE1 4.36Å; W28-F65 HydrophobicContact CE3-CZ 4.4Å; W28-F65 AromaticContact CG-CE1 3.98Å; W28-F65 HydrophobicContact CG-CE1 3.98Å; W28-F65 HydrophobicContact CH2-CZ 4.19Å; W28-F65 HydrophobicContact CZ2-CE1 4.1Å; W28-F65 HydrophobicContact CZ2-CZ 4.15Å; W28-F65 HydrophobicContact CZ3-CZ 4.38Å; W28-Y68 AromaticContact CD1-CE2 3.68Å; W28-Y68 PolarHBondContact N-OH 3.14Å; W28-Q115 HydrophobicContact CH2-CG 3.94Å; W28-Q115 VanDerWaalsContact CH2-OE1 3.24Å; W28-Q115 HydrophobicContact CZ2-CG 3.31Å
29	L	94.5	Very high	93.4	Very high	83 Å²	83	51.6 Å²	51.6	44%	0.435	27%	0.266	S	S	.	.	H	α-helix	trans	-61.8	-44.9	178.7	-178.6	62.3	0	0	0	110.9	F25 V26 F32 I33	F25-L29 WeakPolarHBondContact O-CB 3.36Å; F25-L29 PolarHBondContact O-N 3.35Å; V26-L29 PolarHBondContact O-N 2.9Å; L29-F32 PolarHBondContact O-N 2.64Å; L29-I33 HydrophobicContact CD1-CD1 3.9Å; L29-I33 HydrophobicContact CD1-CG1 4.27Å; L29-I33 HydrophobicContact CG-CD1 3.81Å; L29-I33 WeakPolarHBondContact O-CB 3.49Å; L29-I33 WeakPolarHBondContact O-CG1 3.42Å; L29-I33 PolarHBondContact O-N 2.83Å
30	L	95.9	Very high	93.5	Very high	39 Å²	39	54.8 Å²	54.8	20%	0.204	28%	0.283	C	S	.	.	H	α-helix	trans	-63.3	-47	177.9	-70.3	174.7	0	0	0	111.7	V26 A27 W28 F32 I33 F34 I439 I442	V26-L30 HydrophobicContact CG1-CD1 3.92Å; V26-L30 HydrophobicContact CG1-CG 4.31Å; V26-L30 WeakPolarHBondContact O-CB 3.31Å; V26-L30 VanDerWaalsContact O-CG 3.31Å; V26-L30 WeakPolarHBondContact O-CG 3.27Å; V26-L30 PolarHBondContact O-N 3.5Å; A27-L30 PolarHBondContact O-N 3.34Å; W28-L30 VanDerWaalsContact C-N 3.34Å; W28-L30 PolarHBondContact O-N 3.35Å; L30-F32 VanDerWaalsContact C-N 3.33Å; L30-F32 PolarHBondContact O-N 3.3Å; L30-I33 PolarHBondContact O-N 3.03Å; L30-F34 HydrophobicContact CB-CD2 4.22Å; L30-F34 HydrophobicContact CB-CE2 4.07Å; L30-F34 HydrophobicContact CD2-CE2 4.02Å; L30-F34 HydrophobicContact CD2-CZ 4.45Å; L30-F34 WeakPolarHBondContact O-CB 3.49Å; L30-F34 WeakPolarHBondContact O-CD2 3.34Å; L30-F34 WeakPolarHBondContact O-CG 3.48Å; L30-F34 PolarHBondContact O-N 3.36Å; L30-I439 HydrophobicContact CD1-CG1 4.18Å; L30-I442 HydrophobicContact CB-CD1 4.34Å; L30-I442 HydrophobicContact CB-CG2 4.02Å; L30-I442 HydrophobicContact CD1-CD1 4.15Å
31	Q	94.8	Very high	93.7	Very high	0 Å²	0	58.5 Å²	58.5	0%	0	30%	0.301	C	S	.	.	H	α-helix	trans	-59.7	-44.6	176.3	160.5	-96.2	-49.6	0	0	111.2	A27 W28 N35 L64 Y68 I442 S446	A27-Q31 WeakPolarHBondContact O-CB 3.43Å; A27-Q31 PolarHBondContact O-N 2.59Å; W28-Q31 PolarHBondContact O-N 3.28Å; W28-Q31 PolarHBondContact O-OE1 2.79Å; Q31-N35 WeakPolarHBondContact O-CB 3.44Å; Q31-N35 PolarHBondContact O-N 2.9Å; Q31-L64 PolarHBondContact NE2-O 3.21Å; Q31-Y68 HydrophobicContact CB-CD1 4.35Å; Q31-Y68 HydrophobicContact CB-CE1 3.66Å; Q31-Y68 HydrophobicContact CB-CE2 4.13Å; Q31-Y68 HydrophobicContact CG-CD1 3.81Å; Q31-Y68 HydrophobicContact CG-CD2 4.05Å; Q31-Y68 HydrophobicContact CG-CE1 3.63Å; Q31-Y68 HydrophobicContact CG-CE2 3.86Å; Q31-Y68 HydrophobicContact CG-CG 4.02Å; Q31-I442 HydrophobicContact CB-CG2 3.75Å; Q31-S446 WeakPolarHBondContact CG-OG 3.4Å
32	F	95.5	Very high	93.9	Very high	63 Å²	63	60.7 Å²	60.7	28%	0.276	31%	0.313	S	S	.	.	H	α-helix	trans	-60.2	-49.2	176.7	178.1	-96.5	0	0	0	111.4	W28 L29 L30 H36 F63 L64	W28-F32 VanDerWaalsContact O-CB 3.3Å; W28-F32 WeakPolarHBondContact O-CB 3.42Å; W28-F32 PolarHBondContact O-N 3.08Å; L29-F32 PolarHBondContact O-N 2.64Å; L30-F32 VanDerWaalsContact C-N 3.33Å; L30-F32 PolarHBondContact O-N 3.3Å; F32-H36 AromaticContact CD2-CE1 3.54Å; F32-H36 AromaticContact CD2-ND1 3.78Å; F32-H36 AromaticContact CE2-CE1 3.29Å; F32-H36 WeakPolarHBondContact CE2-CE1 3.47Å; F32-H36 AromaticContact CE2-ND1 3.71Å; F32-H36 AromaticContact CZ-CE1 3.94Å; F32-H36 PolarHBondContact O-N 3.32Å; F32-H36 PolarHBondContact O-ND1 2.97Å; F32-F63 HydrophobicContact CE2-CD1 4.11Å; F32-F63 AromaticContact CE2-CE1 3.63Å; F32-F63 HydrophobicContact CE2-CE1 3.63Å; F32-F63 AromaticContact CE2-CZ 3.98Å; F32-F63 HydrophobicContact CE2-CZ 3.98Å; F32-F63 AromaticContact CZ-CE1 3.83Å; F32-F63 HydrophobicContact CZ-CE1 3.83Å; F32-F63 AromaticContact CZ-CZ 3.95Å; F32-F63 HydrophobicContact CZ-CZ 3.95Å; F32-L64 HydrophobicContact CD2-CD2 4.27Å; F32-L64 HydrophobicContact CE2-CD2 4.06Å
33	I	97.5	Very high	93.7	Very high	66 Å²	66	58.5 Å²	58.5	34%	0.338	30%	0.304	S	S	.	.	H	α-helix	trans	-60.2	-52.5	179.4	-70.8	169.5	0	0	0	110.5	L29 L30 N35 H36 I37	L29-I33 HydrophobicContact CD1-CD1 3.9Å; L29-I33 HydrophobicContact CD1-CG1 4.27Å; L29-I33 HydrophobicContact CG-CD1 3.81Å; L29-I33 WeakPolarHBondContact O-CB 3.49Å; L29-I33 WeakPolarHBondContact O-CG1 3.42Å; L29-I33 PolarHBondContact O-N 2.83Å; L30-I33 PolarHBondContact O-N 3.03Å; I33-N35 PolarHBondContact O-N 2.92Å; I33-H36 PolarHBondContact O-N 3.24Å; I33-I37 HydrophobicContact CG2-CD1 3.52Å; I33-I37 HydrophobicContact CG2-CG1 4.43Å; I33-I37 WeakPolarHBondContact O-CB 3.36Å; I33-I37 VanDerWaalsContact O-CG1 3.3Å; I33-I37 WeakPolarHBondContact O-CG1 3.4Å; I33-I37 PolarHBondContact O-N 3Å; I33-I37 VanDerWaalsContact O-N 3.07Å
34	F	97.5	Very high	93.5	Very high	44 Å²	44	66.9 Å²	66.9	19%	0.193	34%	0.342	C	S	.	.	H	α-helix	trans	-68.3	-36.1	-175.1	-68.7	-51.5	0	0	0	113.2	L30 H36 I37 L38 I439 I442 A443 N447	L30-F34 HydrophobicContact CB-CD2 4.22Å; L30-F34 HydrophobicContact CB-CE2 4.07Å; L30-F34 HydrophobicContact CD2-CE2 4.02Å; L30-F34 HydrophobicContact CD2-CZ 4.45Å; L30-F34 WeakPolarHBondContact O-CB 3.49Å; L30-F34 WeakPolarHBondContact O-CD2 3.34Å; L30-F34 WeakPolarHBondContact O-CG 3.48Å; L30-F34 PolarHBondContact O-N 3.36Å; F34-H36 PolarHBondContact O-N 3.31Å; F34-I37 PolarHBondContact O-N 3.39Å; F34-L38 HydrophobicContact CB-CD1 4.22Å; F34-L38 HydrophobicContact CD1-CD1 4.01Å; F34-L38 HydrophobicContact CG-CD1 4.43Å; F34-L38 WeakPolarHBondContact O-CB 3.5Å; F34-L38 PolarHBondContact O-N 3.03Å; F34-I439 HydrophobicContact CE2-CG2 4.07Å; F34-I439 HydrophobicContact CZ-CG2 3.99Å; F34-I442 HydrophobicContact CD2-CG2 4.29Å; F34-A443 HydrophobicContact CB-CB 4.26Å; F34-A443 HydrophobicContact CD1-CB 3.87Å; F34-A443 VanDerWaalsContact CD2-CA 3.47Å; F34-A443 HydrophobicContact CD2-CB 3.49Å; F34-A443 VanDerWaalsContact CD2-CB 3.49Å; F34-A443 HydrophobicContact CE1-CB 4.03Å; F34-A443 HydrophobicContact CE2-CB 3.64Å; F34-A443 HydrophobicContact CG-CB 3.61Å; F34-A443 HydrophobicContact CZ-CB 3.92Å; F34-N447 PolarHBondContact O-ND2 2.52Å; F34-N447 VanDerWaalsContact O-ND2 3.15Å; F34-N447 PolarHBondContact O-OD1 2.91Å
35	N	95.6	Very high	93.6	Very high	20 Å²	20	67.5 Å²	67.5	11%	0.107	35%	0.347	C	S	.	.	H	α-helix	trans	-65.9	-24.1	178.5	-175.7	78	0	0	0	113.1	Q31 I33 S66 G67 S446	Q31-N35 WeakPolarHBondContact O-CB 3.44Å; Q31-N35 PolarHBondContact O-N 2.9Å; I33-N35 PolarHBondContact O-N 2.92Å; N35-S66 PolarHBondContact ND2-OG 3.46Å; N35-G67 WeakPolarHBondContact OD1-CA 3.41Å; N35-G67 PolarHBondContact OD1-N 3.16Å; N35-S446 PolarHBondContact OD1-O 3.2Å
36	H	96	Very high	93.7	Very high	85 Å²	85	61.4 Å²	61.4	39%	0.394	32%	0.321	S	S	.	.	H	α-helix	trans	-99.2	-21.4	178.8	-67.9	89.9	0	0	0	113.7	F32 I33 F34 F63	F32-H36 AromaticContact CD2-CE1 3.54Å; F32-H36 AromaticContact CD2-ND1 3.78Å; F32-H36 AromaticContact CE2-CE1 3.29Å; F32-H36 WeakPolarHBondContact CE2-CE1 3.47Å; F32-H36 AromaticContact CE2-ND1 3.71Å; F32-H36 AromaticContact CZ-CE1 3.94Å; F32-H36 PolarHBondContact O-N 3.32Å; F32-H36 PolarHBondContact O-ND1 2.97Å; I33-H36 PolarHBondContact O-N 3.24Å; F34-H36 PolarHBondContact O-N 3.31Å; H36-F63 AromaticContact CD2-CE2 3.87Å; H36-F63 PolarHBondContact CE1-O 3.31Å; H36-F63 AromaticContact NE2-CD2 3.48Å; H36-F63 WeakPolarHBondContact NE2-CD2 3.49Å; H36-F63 AromaticContact NE2-CE2 3.22Å; H36-F63 WeakPolarHBondContact NE2-CE2 3.49Å; H36-F63 AromaticContact NE2-CZ 3.83Å
37	I	96.6	Very high	93.7	Very high	126 Å²	126	62.1 Å²	62.1	65%	0.646	32%	0.317	S	S	*	.	H	α-helix	trans	-92.7	-39.7	-179.4	-67	179.1	0	0	0	111.7	I33 F34	I33-I37 HydrophobicContact CG2-CD1 3.52Å; I33-I37 HydrophobicContact CG2-CG1 4.43Å; I33-I37 WeakPolarHBondContact O-CB 3.36Å; I33-I37 VanDerWaalsContact O-CG1 3.3Å; I33-I37 WeakPolarHBondContact O-CG1 3.4Å; I33-I37 PolarHBondContact O-N 3Å; I33-I37 VanDerWaalsContact O-N 3.07Å; F34-I37 PolarHBondContact O-N 3.39Å
38	L	95.5	Very high	93.5	Very high	72 Å²	72	62.9 Å²	62.9	38%	0.377	32%	0.322	S	S	.	.	S	Bend	trans	-92.4	148.4	-177.1	-57.6	177	0	0	0	110.2	F34 A443 N447	F34-L38 HydrophobicContact CB-CD1 4.22Å; F34-L38 HydrophobicContact CD1-CD1 4.01Å; F34-L38 HydrophobicContact CG-CD1 4.43Å; F34-L38 WeakPolarHBondContact O-CB 3.5Å; F34-L38 PolarHBondContact O-N 3.03Å; L38-A443 HydrophobicContact CD1-CB 4.29Å; L38-N447 HydrophobicContact CB-CB 4.37Å; L38-N447 PolarHBondContact O-OD1 2.92Å; L38-N447 VanDerWaalsContact O-OD1 3.14Å
39	A	94.1	Very high	93.2	Very high	80 Å²	80	60.7 Å²	60.7	66%	0.661	32%	0.317	S	S	*	.	P	Polyproline II helix	trans	-82.8	144.3	172.3	0	0	0	0	0	110.4	H41	A39-H41 PolarHBondContact O-N 3.43Å
40	D	93.4	Very high	92	Very high	67 Å²	67	61.6 Å²	61.6	36%	0.358	32%	0.318	S	S	.	.	P	Polyproline II helix	trans	-62	129.6	172.9	-86.5	-17.1	0	0	0	110.8	R70 N447 F448	D40-R70 VanDerWaalsContact CG-NH2 3.28Å; D40-R70 IonicContact OD1-CZ 3.08Å; D40-R70 IonicContact OD1-NE 3.42Å; D40-R70 IonicContact OD1-NH2 3.77Å; D40-R70 PolarHBondContact OD1-NH2 3.22Å; D40-R70 VanDerWaalsContact OD1-NH2 3.08Å; D40-R70 IonicContact OD2-CZ 3.21Å; D40-R70 IonicContact OD2-NH1 3.76Å; D40-R70 PolarHBondContact OD2-NH1 3.3Å; D40-R70 IonicContact OD2-NH2 2.72Å; D40-R70 PolarHBondContact OD2-NH2 3.09Å; D40-N447 WeakPolarHBondContact OD1-CA 3.25Å; D40-F448 HydrophobicContact CB-CD2 4.5Å
41	H	93.8	Very high	90.2	Very high	79 Å²	79	65.1 Å²	65.1	37%	0.366	34%	0.335	S	S	.	.	P	Polyproline II helix	trans	-67.8	136.8	165.4	179.6	60.1	0	0	0	110.2	A39 A43 N447 F448 F449	A39-H41 PolarHBondContact O-N 3.43Å; H41-A43 PolarHBondContact O-N 3.03Å; H41-N447 PolarHBondContact N-O 3Å; H41-F448 HydrophobicContact CB-CB 4.38Å; H41-F448 PolarHBondContact CD2-O 3.33Å; H41-F448 WeakPolarHBondContact O-CB 3.31Å; H41-F449 HydrophobicContact CB-CD1 3.95Å; H41-F449 HydrophobicContact CB-CD2 4Å; H41-F449 HydrophobicContact CB-CE1 3.94Å; H41-F449 HydrophobicContact CB-CE2 3.98Å; H41-F449 HydrophobicContact CB-CG 3.99Å; H41-F449 HydrophobicContact CB-CZ 3.95Å
42	N	90.8	Very high	88.5	Confident	136 Å²	136	70.8 Å²	70.8	73%	0.727	38%	0.375	S	S	*	.			trans	-77.4	72.6	174.7	-170.6	19.4	0	0	0	110.9
43	A	88.7	Confident	87.1	Confident	7 Å²	7	69.8 Å²	69.8	6%	0.058	38%	0.376	C	S	.	.			trans	-76.8	141.8	175.5	0	0	0	0	0	111.6	H41 A45 W71 F448	H41-A43 PolarHBondContact O-N 3.03Å; A43-A45 HydrophobicContact CB-CB 4.24Å; A43-A45 PolarHBondContact O-N 3.29Å; A43-W71 HydrophobicContact CB-CH2 4.13Å; A43-W71 HydrophobicContact CB-CZ2 4.47Å; A43-F448 HydrophobicContact CB-CB 4.17Å; A43-F448 HydrophobicContact CB-CD1 4.38Å
44	E	87.3	Confident	85.7	Confident	180 Å²	180	72.2 Å²	72.2	84%	0.841	39%	0.394	S	S	*	.			trans	-72	19.5	170.4	-63.9	-176.9	168.5	0	0	113.4
45	A	90.5	Very high	84.9	Confident	16 Å²	16	76.9 Å²	76.9	13%	0.132	41%	0.411	C	S	.	.			trans	-70	155.8	178.5	0	0	0	0	0	112	A43 R47 W71 F448	A43-A45 HydrophobicContact CB-CB 4.24Å; A43-A45 PolarHBondContact O-N 3.29Å; A45-R47 PolarHBondContact O-N 3.48Å; A45-W71 HydrophobicContact CB-CE3 4Å; A45-W71 HydrophobicContact CB-CZ3 4.04Å; A45-F448 HydrophobicContact CB-CD1 4.48Å; A45-F448 HydrophobicContact CB-CE1 4.33Å
46	F	93.4	Very high	84.2	Confident	4 Å²	4	81.3 Å²	81.3	2%	0.018	43%	0.434	C	S	.	.			trans	-57.8	134.4	172.6	177.3	-101.8	0	0	0	110.6	Q74 H75 H78 F86 Y278 Y284	F46-Q74 HydrophobicContact CD1-CB 3.81Å; F46-Q74 HydrophobicContact CE1-CB 4.33Å; F46-Q74 WeakPolarHBondContact O-CB 3.21Å; F46-Q74 WeakPolarHBondContact O-CG 3.39Å; F46-H75 WeakPolarHBondContact CB-CE1 3.32Å; F46-H75 VanDerWaalsContact CB-NE2 3.31Å; F46-H75 WeakPolarHBondContact CB-NE2 3.39Å; F46-H75 AromaticContact CD1-CE1 3.46Å; F46-H75 VanDerWaalsContact CD1-CE1 3.46Å; F46-H75 WeakPolarHBondContact CD1-CE1 3.3Å; F46-H75 AromaticContact CD1-CG 3.74Å; F46-H75 AromaticContact CD1-ND1 3.33Å; F46-H75 VanDerWaalsContact CD1-ND1 3.33Å; F46-H75 WeakPolarHBondContact CD1-ND1 3.31Å; F46-H75 AromaticContact CD1-NE2 3.93Å; F46-H75 AromaticContact CD2-CE1 3.94Å; F46-H75 AromaticContact CE1-ND1 3.79Å; F46-H75 AromaticContact CG-CE1 3.26Å; F46-H75 WeakPolarHBondContact CG-CE1 3.1Å; F46-H75 AromaticContact CG-ND1 3.62Å; F46-H75 AromaticContact CG-NE2 3.79Å; F46-H78 HydrophobicContact CE1-CB 3.87Å; F46-H78 HydrophobicContact CZ-CB 4.11Å; F46-H78 AromaticContact CZ-CG 3.89Å; F46-F86 AromaticContact CE2-CD2 3.52Å; F46-F86 HydrophobicContact CE2-CD2 3.52Å; F46-F86 AromaticContact CE2-CE2 3.72Å; F46-F86 HydrophobicContact CE2-CE2 3.72Å; F46-F86 HydrophobicContact CE2-CG 4.2Å; F46-F86 AromaticContact CZ-CD2 3.77Å; F46-F86 HydrophobicContact CZ-CD2 3.77Å; F46-F86 AromaticContact CZ-CE2 3.91Å; F46-F86 HydrophobicContact CZ-CE2 3.91Å; F46-Y278 AromaticContact CD2-CE1 3.99Å; F46-Y278 HydrophobicContact CD2-CE1 3.99Å; F46-Y278 AromaticContact CE2-CE1 3.85Å; F46-Y278 HydrophobicContact CE2-CE1 3.85Å; F46-Y284 HydrophobicContact CD2-CD2 4.28Å; F46-Y284 AromaticContact CD2-CE2 3.71Å; F46-Y284 HydrophobicContact CD2-CE2 3.71Å
47	R	92.1	Very high	83.4	Confident	71 Å²	71	79.3 Å²	79.3	27%	0.268	43%	0.432	S	S	.	.			trans	-133.3	122.1	174.8	-63.9	-176.8	-175.5	-136.4	-0.3	107.2	A45 P49 Y278 F448	A45-R47 PolarHBondContact O-N 3.48Å; R47-P49 WeakPolarHBondContact O-CD 3.36Å; R47-P49 VanDerWaalsContact O-N 3.11Å; R47-Y278 PolarHBondContact N-OH 2.96Å; R47-Y278 PolarHBondContact O-OH 2.87Å; R47-F448 HydrophobicContact CG-CZ 4.22Å; R47-F448 VanDerWaalsContact CZ-CE2 3.43Å
48	S	89.4	Confident	82.6	Confident	19 Å²	19	76 Å²	76	13%	0.133	42%	0.416	C	S	.	.			trans	-59.9	117.7	-178.2	-177.7	0	0	0	0	109.8	Q50 H78	S48-Q50 PolarHBondContact O-N 2.93Å; S48-H78 PolarHBondContact OG-ND1 3.43Å
49	P	84.9	Confident	81.9	Confident	18 Å²	18	79.6 Å²	79.6	12%	0.117	42%	0.424	C	S	.	.	S	Bend	trans	-66.7	126.9	172.7	25.9	-30.9	0	0	0	108.6	R47 F86 I274 Y275 Y278	R47-P49 WeakPolarHBondContact O-CD 3.36Å; R47-P49 VanDerWaalsContact O-N 3.11Å; P49-F86 HydrophobicContact CG-CE2 4.47Å; P49-F86 HydrophobicContact CG-CZ 4.18Å; P49-I274 HydrophobicContact CB-CG2 4.27Å; P49-Y275 HydrophobicContact CG-CD1 3.66Å; P49-Y275 HydrophobicContact CG-CE1 3.88Å; P49-Y278 HydrophobicContact CB-CD2 4.25Å; P49-Y278 HydrophobicContact CB-CG 4.19Å; P49-Y278 HydrophobicContact CG-CD1 3.96Å; P49-Y278 HydrophobicContact CG-CD2 4.32Å; P49-Y278 HydrophobicContact CG-CG 3.85Å
50	Q	69.3	Low	81.6	Confident	101 Å²	101	79.9 Å²	79.9	47%	0.472	41%	0.414	S	S	.	.			trans	64.5	106.7	179.5	-60.5	-173.7	-39	0	0	117.5	S48 N271 I274	S48-Q50 PolarHBondContact O-N 2.93Å; Q50-N271 PolarHBondContact OE1-ND2 3.5Å; Q50-I274 VanDerWaalsContact CD-CD1 3.47Å; Q50-I274 HydrophobicContact CG-CG2 4.38Å
51	M	57.9	Low	81.1	Confident	114 Å²	114	78.2 Å²	78.2	56%	0.562	41%	0.406	S	S	*	.			trans	-153.1	42.4	157.6	-82.5	-163.7	71.9	0	0	111.6	S53 T81	M51-S53 PolarHBondContact O-N 3.28Å; M51-T81 HydrophobicContact CE-CG2 3.52Å; M51-T81 HydrophobicContact SD-CG2 3.78Å
52	S	58.5	Low	80.7	Confident	119 Å²	119	79 Å²	79	83%	0.832	41%	0.413	S	S	*	.			trans	-74.6	96.3	169.7	57.9	0	0	0	0	109
53	S	67.1	Low	80.6	Confident	42 Å²	42	77.8 Å²	77.8	29%	0.294	40%	0.401	S	S	.	.			trans	-69.8	139.3	172.8	177.8	0	0	0	0	110.8	M51 Y55 D58	M51-S53 PolarHBondContact O-N 3.28Å; S53-Y55 WeakPolarHBondContact OG-CD2 3.48Å; S53-Y55 PolarHBondContact OG-N 2.86Å; S53-Y55 VanDerWaalsContact OG-N 3.14Å; S53-D58 VanDerWaalsContact CB-CB 3.5Å; S53-D58 VanDerWaalsContact CB-OD2 3.24Å; S53-D58 WeakPolarHBondContact CB-OD2 3.37Å; S53-D58 WeakPolarHBondContact OG-CB 3.32Å; S53-D58 PolarHBondContact OG-OD2 3.49Å
54	T	68	Low	80.7	Confident	116 Å²	116	80.7 Å²	80.7	71%	0.712	42%	0.415	S	S	*	.			trans	-82	-16.4	173.9	49.1	0	0	0	0	112.6
55	Y	79.5	Confident	80.9	Confident	142 Å²	142	73.9 Å²	73.9	56%	0.557	38%	0.383	S	S	*	.			trans	-76	137.9	-174.8	-59.8	-69.2	0	0	0	112	S53 A57 D58 R59	S53-Y55 WeakPolarHBondContact OG-CD2 3.48Å; S53-Y55 PolarHBondContact OG-N 2.86Å; S53-Y55 VanDerWaalsContact OG-N 3.14Å; Y55-A57 VanDerWaalsContact C-N 3.32Å; Y55-A57 PolarHBondContact O-N 3.47Å; Y55-D58 PolarHBondContact O-N 3.24Å; Y55-R59 PolarHBondContact O-N 3.16Å
56	L	81.1	Confident	80.8	Confident	114 Å²	114	73.8 Å²	73.8	60%	0.597	38%	0.381	S	S	*	.	H	α-helix	trans	-60.8	-40.9	178.7	-180	65	0	0	0	112.2	D58 R59 I60	L56-D58 VanDerWaalsContact C-N 3.31Å; L56-D58 PolarHBondContact O-N 2.94Å; L56-R59 WeakPolarHBondContact O-CB 3.48Å; L56-R59 PolarHBondContact O-N 3.4Å; L56-R59 VanDerWaalsContact O-N 3.17Å; L56-I60 HydrophobicContact CG-CD1 4.09Å; L56-I60 WeakPolarHBondContact O-CG1 3.35Å; L56-I60 PolarHBondContact O-N 3.48Å
57	A	79.5	Confident	80.7	Confident	42 Å²	42	73.6 Å²	73.6	35%	0.347	38%	0.38	S	S	.	.	H	α-helix	trans	-62.2	-40.6	-179.2	0	0	0	0	0	111.7	Y55 R59 I60 V61 P109	Y55-A57 VanDerWaalsContact C-N 3.32Å; Y55-A57 PolarHBondContact O-N 3.47Å; A57-R59 VanDerWaalsContact C-N 3.33Å; A57-R59 PolarHBondContact O-N 2.76Å; A57-I60 PolarHBondContact O-N 2.87Å; A57-V61 VanDerWaalsContact O-CG2 3.31Å; A57-V61 WeakPolarHBondContact O-CG2 3.36Å; A57-V61 PolarHBondContact O-N 2.85Å; A57-P109 HydrophobicContact CB-CG 3.51Å
58	D	78.9	Confident	80.7	Confident	56 Å²	56	70.6 Å²	70.6	30%	0.299	37%	0.369	S	S	.	.	H	α-helix	trans	-66.2	-37.4	176.5	-64.5	-15.2	0	0	0	111.2	S53 Y55 L56 V61 D62	S53-D58 VanDerWaalsContact CB-CB 3.5Å; S53-D58 VanDerWaalsContact CB-OD2 3.24Å; S53-D58 WeakPolarHBondContact CB-OD2 3.37Å; S53-D58 WeakPolarHBondContact OG-CB 3.32Å; S53-D58 PolarHBondContact OG-OD2 3.49Å; Y55-D58 PolarHBondContact O-N 3.24Å; L56-D58 VanDerWaalsContact C-N 3.31Å; L56-D58 PolarHBondContact O-N 2.94Å; D58-V61 PolarHBondContact O-N 2.67Å; D58-D62 VanDerWaalsContact O-CB 3.26Å; D58-D62 WeakPolarHBondContact O-CB 3.49Å; D58-D62 PolarHBondContact O-N 2.84Å
59	R	82.7	Confident	80.7	Confident	149 Å²	149	70.9 Å²	70.9	56%	0.562	37%	0.37	S	S	*	.	H	α-helix	trans	-64.3	-39.2	173.5	-72.9	-172	-79.2	178.8	-6.1	113	Y55 L56 A57 F63	Y55-R59 PolarHBondContact O-N 3.16Å; L56-R59 WeakPolarHBondContact O-CB 3.48Å; L56-R59 PolarHBondContact O-N 3.4Å; L56-R59 VanDerWaalsContact O-N 3.17Å; A57-R59 VanDerWaalsContact C-N 3.33Å; A57-R59 PolarHBondContact O-N 2.76Å; R59-F63 VanDerWaalsContact O-CB 3.3Å; R59-F63 WeakPolarHBondContact O-CB 2.95Å; R59-F63 PolarHBondContact O-N 3.29Å
60	I	86.4	Confident	81	Confident	86 Å²	86	71.7 Å²	71.7	44%	0.441	37%	0.371	S	S	.	.	H	α-helix	trans	-65.1	-45.3	175.2	-67.7	168.2	0	0	0	110	L56 A57 F63 L64	L56-I60 HydrophobicContact CG-CD1 4.09Å; L56-I60 WeakPolarHBondContact O-CG1 3.35Å; L56-I60 PolarHBondContact O-N 3.48Å; A57-I60 PolarHBondContact O-N 2.87Å; I60-F63 PolarHBondContact O-N 2.92Å; I60-L64 HydrophobicContact CG2-CD1 3.87Å; I60-L64 HydrophobicContact CG2-CG 4.45Å; I60-L64 WeakPolarHBondContact O-CB 2.85Å; I60-L64 VanDerWaalsContact O-CG 3.29Å; I60-L64 WeakPolarHBondContact O-CG 3.47Å; I60-L64 PolarHBondContact O-N 3.47Å
61	V	83.8	Confident	82.2	Confident	31 Å²	31	69.8 Å²	69.8	19%	0.188	36%	0.359	C	S	.	.	H	α-helix	trans	-63.7	-42.9	178.7	170.1	0	0	0	0	111.1	A57 D58 L64 F65 P109 I111	A57-V61 VanDerWaalsContact O-CG2 3.31Å; A57-V61 WeakPolarHBondContact O-CG2 3.36Å; A57-V61 PolarHBondContact O-N 2.85Å; D58-V61 PolarHBondContact O-N 2.67Å; V61-L64 PolarHBondContact O-N 2.89Å; V61-F65 HydrophobicContact CG1-CD2 4.38Å; V61-F65 WeakPolarHBondContact O-CB 3.49Å; V61-F65 PolarHBondContact O-N 3.01Å; V61-P109 HydrophobicContact CG2-CB 4.38Å; V61-P109 HydrophobicContact CG2-CG 4.25Å; V61-I111 HydrophobicContact CG1-CD1 3.21Å; V61-I111 HydrophobicContact CG1-CG1 3.89Å
62	D	85.2	Confident	83.9	Confident	95 Å²	95	65.5 Å²	65.5	51%	0.508	34%	0.339	S	S	.	.	H	α-helix	trans	-63.5	-44.6	176.1	-171.2	59.4	0	0	0	111.4	D58 L64 F65 S66	D58-D62 VanDerWaalsContact O-CB 3.26Å; D58-D62 WeakPolarHBondContact O-CB 3.49Å; D58-D62 PolarHBondContact O-N 2.84Å; D62-L64 VanDerWaalsContact C-N 3.31Å; D62-L64 PolarHBondContact O-N 3.5Å; D62-F65 PolarHBondContact O-N 3.45Å; D62-S66 WeakPolarHBondContact O-CA 3.18Å; D62-S66 WeakPolarHBondContact O-CB 3.43Å; D62-S66 PolarHBondContact O-N 2.83Å; D62-S66 PolarHBondContact O-OG 2.94Å
63	F	89.4	Confident	85.5	Confident	112 Å²	112	59.9 Å²	59.9	49%	0.491	30%	0.299	S	S	.	.	H	α-helix	trans	-57.8	-43.9	173.7	178.5	-104.4	0	0	0	111.9	F32 H36 R59 I60	F32-F63 HydrophobicContact CE2-CD1 4.11Å; F32-F63 AromaticContact CE2-CE1 3.63Å; F32-F63 HydrophobicContact CE2-CE1 3.63Å; F32-F63 AromaticContact CE2-CZ 3.98Å; F32-F63 HydrophobicContact CE2-CZ 3.98Å; F32-F63 AromaticContact CZ-CE1 3.83Å; F32-F63 HydrophobicContact CZ-CE1 3.83Å; F32-F63 AromaticContact CZ-CZ 3.95Å; F32-F63 HydrophobicContact CZ-CZ 3.95Å; H36-F63 AromaticContact CD2-CE2 3.87Å; H36-F63 PolarHBondContact CE1-O 3.31Å; H36-F63 AromaticContact NE2-CD2 3.48Å; H36-F63 WeakPolarHBondContact NE2-CD2 3.49Å; H36-F63 AromaticContact NE2-CE2 3.22Å; H36-F63 WeakPolarHBondContact NE2-CE2 3.49Å; H36-F63 AromaticContact NE2-CZ 3.83Å; R59-F63 VanDerWaalsContact O-CB 3.3Å; R59-F63 WeakPolarHBondContact O-CB 2.95Å; R59-F63 PolarHBondContact O-N 3.29Å; I60-F63 PolarHBondContact O-N 2.92Å
64	L	90.1	Very high	86.8	Confident	67 Å²	67	59 Å²	59	35%	0.351	29%	0.291	S	S	.	.	H	α-helix	trans	-75.8	-36.4	-178.1	-68	173.5	0	0	0	113.3	Q31 F32 I60 V61 D62	Q31-L64 PolarHBondContact NE2-O 3.21Å; F32-L64 HydrophobicContact CD2-CD2 4.27Å; F32-L64 HydrophobicContact CE2-CD2 4.06Å; I60-L64 HydrophobicContact CG2-CD1 3.87Å; I60-L64 HydrophobicContact CG2-CG 4.45Å; I60-L64 WeakPolarHBondContact O-CB 2.85Å; I60-L64 VanDerWaalsContact O-CG 3.29Å; I60-L64 WeakPolarHBondContact O-CG 3.47Å; I60-L64 PolarHBondContact O-N 3.47Å; V61-L64 PolarHBondContact O-N 2.89Å; D62-L64 VanDerWaalsContact C-N 3.31Å; D62-L64 PolarHBondContact O-N 3.5Å
65	F	90.6	Very high	88.1	Confident	38 Å²	38	54 Å²	54	17%	0.167	26%	0.259	C	S	.	.	H	α-helix	trans	-129	6.5	-163.4	-61.2	-70.3	0	0	0	115.5	W28 V61 D62 G67 Y68	W28-F65 HydrophobicContact CB-CE1 4.44Å; W28-F65 AromaticContact CD2-CE1 3.88Å; W28-F65 HydrophobicContact CD2-CE1 3.88Å; W28-F65 HydrophobicContact CD2-CZ 4.34Å; W28-F65 AromaticContact CE2-CE1 3.84Å; W28-F65 HydrophobicContact CE3-CE1 4.36Å; W28-F65 HydrophobicContact CE3-CZ 4.4Å; W28-F65 AromaticContact CG-CE1 3.98Å; W28-F65 HydrophobicContact CG-CE1 3.98Å; W28-F65 HydrophobicContact CH2-CZ 4.19Å; W28-F65 HydrophobicContact CZ2-CE1 4.1Å; W28-F65 HydrophobicContact CZ2-CZ 4.15Å; W28-F65 HydrophobicContact CZ3-CZ 4.38Å; V61-F65 HydrophobicContact CG1-CD2 4.38Å; V61-F65 WeakPolarHBondContact O-CB 3.49Å; V61-F65 PolarHBondContact O-N 3.01Å; D62-F65 PolarHBondContact O-N 3.45Å; F65-G67 PolarHBondContact O-N 2.92Å; F65-G67 VanDerWaalsContact O-N 3.08Å; F65-Y68 HydrophobicContact CD1-CD2 4.15Å; F65-Y68 HydrophobicContact CD1-CE2 4.3Å; F65-Y68 PolarHBondContact O-N 3.26Å
66	S	89.4	Confident	88.7	Confident	13 Å²	13	47.4 Å²	47.4	9%	0.091	23%	0.233	C	C	.	.	G	3₁₀ helix	trans	-54	-31.6	179	45.4	0	0	0	0	113.1	N35 D62 Y68 T69	N35-S66 PolarHBondContact ND2-OG 3.46Å; D62-S66 WeakPolarHBondContact O-CA 3.18Å; D62-S66 WeakPolarHBondContact O-CB 3.43Å; D62-S66 PolarHBondContact O-N 2.83Å; D62-S66 PolarHBondContact O-OG 2.94Å; S66-Y68 PolarHBondContact O-N 3.45Å; S66-Y68 VanDerWaalsContact O-N 3.1Å; S66-T69 WeakPolarHBondContact O-CB 3.49Å; S66-T69 PolarHBondContact O-N 3.4Å; S66-T69 PolarHBondContact O-OG1 2.96Å
67	G	91.1	Very high	89.2	Confident	0 Å²	0	43.5 Å²	43.5	0%	0	21%	0.213	C	C	.	.	G	3₁₀ helix	trans	-61.3	-16.2	174.4	0	0	0	0	0	114.9	N35 F65 S446	N35-G67 WeakPolarHBondContact OD1-CA 3.41Å; N35-G67 PolarHBondContact OD1-N 3.16Å; F65-G67 PolarHBondContact O-N 2.92Å; F65-G67 VanDerWaalsContact O-N 3.08Å; G67-S446 WeakPolarHBondContact O-CA 3.43Å; G67-S446 WeakPolarHBondContact O-CB 3.42Å; G67-S446 PolarHBondContact O-OG 3.42Å
68	Y	91.4	Very high	89.8	Confident	9 Å²	9	41.5 Å²	41.5	4%	0.035	20%	0.197	C	C	.	.	G	3₁₀ helix	trans	-92.9	-3.4	172.3	-71.2	-38	0	0	0	114.3	A27 W28 Q31 F65 S66 R70 S73 H156	A27-Y68 PolarHBondContact O-OH 3.32Å; W28-Y68 AromaticContact CD1-CE2 3.68Å; W28-Y68 PolarHBondContact N-OH 3.14Å; Q31-Y68 HydrophobicContact CB-CD1 4.35Å; Q31-Y68 HydrophobicContact CB-CE1 3.66Å; Q31-Y68 HydrophobicContact CB-CE2 4.13Å; Q31-Y68 HydrophobicContact CG-CD1 3.81Å; Q31-Y68 HydrophobicContact CG-CD2 4.05Å; Q31-Y68 HydrophobicContact CG-CE1 3.63Å; Q31-Y68 HydrophobicContact CG-CE2 3.86Å; Q31-Y68 HydrophobicContact CG-CG 4.02Å; F65-Y68 HydrophobicContact CD1-CD2 4.15Å; F65-Y68 HydrophobicContact CD1-CE2 4.3Å; F65-Y68 PolarHBondContact O-N 3.26Å; S66-Y68 PolarHBondContact O-N 3.45Å; S66-Y68 VanDerWaalsContact O-N 3.1Å; Y68-R70 VanDerWaalsContact C-N 3.32Å; Y68-S73 WeakPolarHBondContact O-CB 3.49Å; Y68-S73 PolarHBondContact O-OG 3.33Å; Y68-H156 HydrophobicContact CE1-CB 4.31Å
69	T	90.4	Very high	90.5	Very high	24 Å²	24	39 Å²	39	15%	0.147	18%	0.183	C	C	.	.	S	Bend	trans	-89	4.6	-179.8	73	0	0	0	0	113	S66 S73 Q74 L77 I158	S66-T69 WeakPolarHBondContact O-CB 3.49Å; S66-T69 PolarHBondContact O-N 3.4Å; S66-T69 PolarHBondContact O-OG1 2.96Å; T69-S73 VanDerWaalsContact C-CB 3.46Å; T69-Q74 VanDerWaalsContact O-CG 3.24Å; T69-Q74 WeakPolarHBondContact O-CG 3.44Å; T69-Q74 PolarHBondContact O-NE2 3.13Å; T69-L77 HydrophobicContact CG2-CD1 3.82Å; T69-I158 HydrophobicContact CG2-CD1 4.33Å
70	R	91	Very high	90.9	Very high	35 Å²	35	32 Å²	32	13%	0.132	16%	0.158	C	C	.	.	S	Bend	trans	-83	162.8	-175.8	-47.5	-41.3	-166	164.2	5.7	112.7	D40 Y68 S73 H445 S446 F448	D40-R70 VanDerWaalsContact CG-NH2 3.28Å; D40-R70 IonicContact OD1-CZ 3.08Å; D40-R70 IonicContact OD1-NE 3.42Å; D40-R70 IonicContact OD1-NH2 3.77Å; D40-R70 PolarHBondContact OD1-NH2 3.22Å; D40-R70 VanDerWaalsContact OD1-NH2 3.08Å; D40-R70 IonicContact OD2-CZ 3.21Å; D40-R70 IonicContact OD2-NH1 3.76Å; D40-R70 PolarHBondContact OD2-NH1 3.3Å; D40-R70 IonicContact OD2-NH2 2.72Å; D40-R70 PolarHBondContact OD2-NH2 3.09Å; Y68-R70 VanDerWaalsContact C-N 3.32Å; R70-S73 WeakPolarHBondContact O-CB 3.5Å; R70-S73 PolarHBondContact O-N 3.39Å; R70-S73 PolarHBondContact O-OG 3.17Å; R70-H445 VanDerWaalsContact CB-O 3.23Å; R70-H445 WeakPolarHBondContact CB-O 3.48Å; R70-H445 WeakPolarHBondContact CG-O 3.47Å; R70-H445 PolarHBondContact O-CE1 2.65Å; R70-S446 VanDerWaalsContact CG-O 3.31Å; R70-S446 WeakPolarHBondContact CG-O 3.5Å; R70-S446 PolarHBondContact NE-O 3.48Å; R70-F448 HydrophobicContact CB-CD1 4.02Å; R70-F448 HydrophobicContact CB-CD2 4.46Å; R70-F448 HydrophobicContact CB-CE1 3.96Å; R70-F448 HydrophobicContact CB-CE2 4.45Å; R70-F448 HydrophobicContact CB-CG 4.28Å; R70-F448 HydrophobicContact CB-CZ 4.18Å; R70-F448 VanDerWaalsContact CD-CE2 3.43Å; R70-F448 HydrophobicContact CG-CD2 4.22Å; R70-F448 HydrophobicContact CG-CE2 4.27Å; R70-F448 HydrophobicContact CG-CG 4.42Å; R70-F448 HydrophobicContact CG-CZ 4.45Å
71	W	94	Very high	90.9	Very high	61 Å²	61	31.3 Å²	31.3	23%	0.231	16%	0.157	C	C	.	.	T	Hydrogen-bonded Turn	trans	56.4	-132.9	176.2	-62.5	105.3	0	0	0	112.9	A43 A45 S73 Q74 Y159 H445 F448 F449 P450	A43-W71 HydrophobicContact CB-CH2 4.13Å; A43-W71 HydrophobicContact CB-CZ2 4.47Å; A45-W71 HydrophobicContact CB-CE3 4Å; A45-W71 HydrophobicContact CB-CZ3 4.04Å; W71-S73 PolarHBondContact O-N 2.91Å; W71-Q74 WeakPolarHBondContact O-CB 3.49Å; W71-Q74 PolarHBondContact O-N 3.11Å; W71-Y159 WeakPolarHBondContact CB-OH 3.42Å; W71-H445 AromaticContact CD1-CD2 3.51Å; W71-H445 AromaticContact CD1-CG 3.92Å; W71-H445 AromaticContact CD1-NE2 3.69Å; W71-F448 HydrophobicContact CD2-CD1 4.45Å; W71-F448 WeakPolarHBondContact CZ2-O 3.44Å; W71-F449 VanDerWaalsContact CZ2-C 3.44Å; W71-F449 WeakPolarHBondContact CZ2-O 3.47Å; W71-F449 PolarHBondContact NE1-O 2.93Å; W71-P450 HydrophobicContact CH2-CB 4.49Å
72	D	93.9	Very high	91.1	Very high	25 Å²	25	32.3 Å²	32.3	13%	0.134	16%	0.163	C	C	.	.	H	α-helix	trans	-60.1	-22.5	-174.9	-62.1	-23.7	0	0	0	112.7	Q74 H75 F76 F92 Y159 R382	D72-Q74 PolarHBondContact O-N 2.01Å; D72-H75 WeakPolarHBondContact O-CB 3.33Å; D72-H75 PolarHBondContact O-N 2.94Å; D72-F76 HydrophobicContact CB-CE2 4.29Å; D72-F76 VanDerWaalsContact O-CD2 3.26Å; D72-F76 WeakPolarHBondContact O-CD2 3.03Å; D72-F76 PolarHBondContact O-N 3.01Å; D72-F92 HydrophobicContact CB-CD1 4.45Å; D72-F92 HydrophobicContact CB-CE1 3.55Å; D72-F92 HydrophobicContact CB-CZ 4.07Å; D72-Y159 HydrophobicContact CB-CD1 4.28Å; D72-Y159 HydrophobicContact CB-CE1 3.51Å; D72-Y159 HydrophobicContact CB-CE2 4.16Å; D72-Y159 VanDerWaalsContact CB-CZ 3.49Å; D72-Y159 PolarHBondContact N-OH 3.37Å; D72-Y159 VanDerWaalsContact N-OH 3.16Å; D72-Y159 WeakPolarHBondContact OD2-CE1 3.44Å; D72-R382 IonicContact OD2-CZ 3.88Å; D72-R382 IonicContact OD2-NH1 3.16Å; D72-R382 PolarHBondContact OD2-NH1 3.47Å; D72-R382 IonicContact OD2-NH2 2.69Å
73	S	93	Very high	91.4	Very high	0 Å²	0	28.2 Å²	28.2	0%	0	14%	0.143	C	C	.	.	H	α-helix	trans	-54.8	-33.7	172	-62.9	0	0	0	0	113	Y68 T69 R70 W71 H75 F76 L77 I158 Y159	Y68-S73 WeakPolarHBondContact O-CB 3.49Å; Y68-S73 PolarHBondContact O-OG 3.33Å; T69-S73 VanDerWaalsContact C-CB 3.46Å; R70-S73 WeakPolarHBondContact O-CB 3.5Å; R70-S73 PolarHBondContact O-N 3.39Å; R70-S73 PolarHBondContact O-OG 3.17Å; W71-S73 PolarHBondContact O-N 2.91Å; S73-H75 VanDerWaalsContact C-N 3.31Å; S73-H75 PolarHBondContact O-N 3.4Å; S73-F76 PolarHBondContact O-N 3.22Å; S73-L77 WeakPolarHBondContact O-CB 3.26Å; S73-L77 WeakPolarHBondContact O-CG 3.41Å; S73-L77 PolarHBondContact O-N 3.23Å; S73-I158 PolarHBondContact OG-N 2.59Å; S73-I158 PolarHBondContact OG-O 3.22Å; S73-Y159 WeakPolarHBondContact OG-CD2 3.12Å; S73-Y159 WeakPolarHBondContact OG-CE2 3.44Å
74	Q	92.9	Very high	91.6	Very high	24 Å²	24	23.7 Å²	23.7	11%	0.112	12%	0.123	C	C	.	.	H	α-helix	trans	-61.9	-40.9	176.7	-72.6	-69.4	-43.7	0	0	111.2	F46 T69 W71 D72 H78	F46-Q74 HydrophobicContact CD1-CB 3.81Å; F46-Q74 HydrophobicContact CE1-CB 4.33Å; F46-Q74 WeakPolarHBondContact O-CB 3.21Å; F46-Q74 WeakPolarHBondContact O-CG 3.39Å; T69-Q74 VanDerWaalsContact O-CG 3.24Å; T69-Q74 WeakPolarHBondContact O-CG 3.44Å; T69-Q74 PolarHBondContact O-NE2 3.13Å; W71-Q74 WeakPolarHBondContact O-CB 3.49Å; W71-Q74 PolarHBondContact O-N 3.11Å; D72-Q74 PolarHBondContact O-N 2.01Å; Q74-H78 VanDerWaalsContact O-CB 3.23Å; Q74-H78 WeakPolarHBondContact O-CB 3.24Å; Q74-H78 PolarHBondContact O-N 3.04Å
75	H	94.8	Very high	91.7	Very high	12 Å²	12	20.5 Å²	20.5	6%	0.056	11%	0.107	C	C	.	.	H	α-helix	trans	-65	-48.8	176.2	-67	-75.7	0	0	0	110.8	F46 D72 S73 L77 H78 I79 N88 N89 F92	F46-H75 WeakPolarHBondContact CB-CE1 3.32Å; F46-H75 VanDerWaalsContact CB-NE2 3.31Å; F46-H75 WeakPolarHBondContact CB-NE2 3.39Å; F46-H75 AromaticContact CD1-CE1 3.46Å; F46-H75 VanDerWaalsContact CD1-CE1 3.46Å; F46-H75 WeakPolarHBondContact CD1-CE1 3.3Å; F46-H75 AromaticContact CD1-CG 3.74Å; F46-H75 AromaticContact CD1-ND1 3.33Å; F46-H75 VanDerWaalsContact CD1-ND1 3.33Å; F46-H75 WeakPolarHBondContact CD1-ND1 3.31Å; F46-H75 AromaticContact CD1-NE2 3.93Å; F46-H75 AromaticContact CD2-CE1 3.94Å; F46-H75 AromaticContact CE1-ND1 3.79Å; F46-H75 AromaticContact CG-CE1 3.26Å; F46-H75 WeakPolarHBondContact CG-CE1 3.1Å; F46-H75 AromaticContact CG-ND1 3.62Å; F46-H75 AromaticContact CG-NE2 3.79Å; D72-H75 WeakPolarHBondContact O-CB 3.33Å; D72-H75 PolarHBondContact O-N 2.94Å; S73-H75 VanDerWaalsContact C-N 3.31Å; S73-H75 PolarHBondContact O-N 3.4Å; H75-L77 VanDerWaalsContact C-N 3.35Å; H75-L77 PolarHBondContact O-N 3.34Å; H75-H78 PolarHBondContact O-N 2.84Å; H75-I79 WeakPolarHBondContact O-CB 3.37Å; H75-I79 VanDerWaalsContact O-CD1 3.32Å; H75-I79 WeakPolarHBondContact O-CD1 3.43Å; H75-I79 WeakPolarHBondContact O-CG1 3.27Å; H75-I79 PolarHBondContact O-N 3.13Å; H75-N88 PolarHBondContact CE1-ND2 3.37Å; H75-N89 PolarHBondContact ND1-OD1 3.08Å; H75-F92 HydrophobicContact CB-CD1 4.24Å; H75-F92 HydrophobicContact CB-CD2 3.44Å; H75-F92 VanDerWaalsContact CB-CD2 3.44Å; H75-F92 HydrophobicContact CB-CE1 4.31Å; H75-F92 HydrophobicContact CB-CE2 3.51Å; H75-F92 HydrophobicContact CB-CG 3.82Å; H75-F92 HydrophobicContact CB-CZ 3.95Å; H75-F92 AromaticContact CD2-CE2 3.22Å; H75-F92 WeakPolarHBondContact CD2-CE2 3.39Å; H75-F92 AromaticContact CD2-CZ 3.29Å; H75-F92 WeakPolarHBondContact CD2-CZ 3.29Å; H75-F92 AromaticContact CE1-CE2 3.9Å; H75-F92 AromaticContact CG-CD2 3.63Å; H75-F92 AromaticContact CG-CE2 3.19Å; H75-F92 AromaticContact CG-CZ 3.69Å; H75-F92 AromaticContact ND1-CE2 3.64Å; H75-F92 AromaticContact NE2-CE2 3.69Å; H75-F92 AromaticContact NE2-CZ 3.95Å
76	F	93.9	Very high	91.8	Very high	2 Å²	2	18.7 Å²	18.7	1%	0.009	10%	0.099	C	C	.	.	H	α-helix	trans	-60.8	-42.2	179.8	-69.9	-65	0	0	0	112.6	D72 S73 A80 F92 L96 P97 I158	D72-F76 HydrophobicContact CB-CE2 4.29Å; D72-F76 VanDerWaalsContact O-CD2 3.26Å; D72-F76 WeakPolarHBondContact O-CD2 3.03Å; D72-F76 PolarHBondContact O-N 3.01Å; S73-F76 PolarHBondContact O-N 3.22Å; F76-A80 WeakPolarHBondContact O-CB 3.43Å; F76-A80 PolarHBondContact O-N 3.43Å; F76-F92 HydrophobicContact CD1-CB 4.21Å; F76-F92 HydrophobicContact CD2-CD1 4.39Å; F76-F92 HydrophobicContact CE1-CB 3.89Å; F76-F92 HydrophobicContact CE1-CD1 4.04Å; F76-F92 HydrophobicContact CE1-CG 4.43Å; F76-F92 AromaticContact CE2-CD1 3.83Å; F76-F92 HydrophobicContact CE2-CD1 3.83Å; F76-F92 HydrophobicContact CE2-CE1 4.36Å; F76-F92 HydrophobicContact CZ-CB 4.35Å; F76-F92 AromaticContact CZ-CD1 3.65Å; F76-F92 HydrophobicContact CZ-CD1 3.65Å; F76-F92 HydrophobicContact CZ-CG 4.46Å; F76-L96 HydrophobicContact CB-CD2 4.26Å; F76-L96 HydrophobicContact CD1-CB 4.31Å; F76-L96 HydrophobicContact CD1-CD2 3.92Å; F76-L96 HydrophobicContact CD1-CG 4.34Å; F76-L96 HydrophobicContact CD2-CD2 4.13Å; F76-L96 HydrophobicContact CE1-CB 4.43Å; F76-L96 HydrophobicContact CE1-CD2 4.22Å; F76-L96 HydrophobicContact CE2-CD2 4.42Å; F76-L96 HydrophobicContact CG-CD2 3.86Å; F76-L96 HydrophobicContact CZ-CD2 4.45Å; F76-P97 HydrophobicContact CB-CG 4.44Å; F76-P97 HydrophobicContact CD1-CG 3.73Å; F76-I158 HydrophobicContact CB-CG2 4.08Å; F76-I158 WeakPolarHBondContact CD2-O 3.31Å
77	L	90.7	Very high	92.1	Very high	33 Å²	33	18.2 Å²	18.2	17%	0.173	10%	0.095	C	C	.	.	H	α-helix	trans	-66.3	-43.4	176.3	-76.4	174	0	0	0	112.5	T69 S73 H75 I79 A80 T81 I158	T69-L77 HydrophobicContact CG2-CD1 3.82Å; S73-L77 WeakPolarHBondContact O-CB 3.26Å; S73-L77 WeakPolarHBondContact O-CG 3.41Å; S73-L77 PolarHBondContact O-N 3.23Å; H75-L77 VanDerWaalsContact C-N 3.35Å; H75-L77 PolarHBondContact O-N 3.34Å; L77-I79 PolarHBondContact O-N 2.91Å; L77-A80 PolarHBondContact O-N 3.13Å; L77-T81 WeakPolarHBondContact O-CB 3.41Å; L77-T81 WeakPolarHBondContact O-CG2 3.36Å; L77-T81 PolarHBondContact O-N 2.77Å; L77-T81 PolarHBondContact O-OG1 3.3Å; L77-I158 HydrophobicContact CD1-CD1 3.84Å; L77-I158 HydrophobicContact CD2-CD1 3.81Å; L77-I158 HydrophobicContact CD2-CG2 4.44Å; L77-I158 HydrophobicContact CG-CD1 3.92Å; L77-I158 HydrophobicContact CG-CG2 4.29Å
78	H	91.8	Very high	92.3	Very high	0 Å²	0	18.4 Å²	18.4	0%	0	10%	0.096	C	C	.	.	H	α-helix	trans	-61.2	-45.7	176.5	-173.8	84.7	0	0	0	111.3	F46 S48 Q74 H75 A80 T81 V82 G83 T85 F86 N89 Y275	F46-H78 HydrophobicContact CE1-CB 3.87Å; F46-H78 HydrophobicContact CZ-CB 4.11Å; F46-H78 AromaticContact CZ-CG 3.89Å; S48-H78 PolarHBondContact OG-ND1 3.43Å; Q74-H78 VanDerWaalsContact O-CB 3.23Å; Q74-H78 WeakPolarHBondContact O-CB 3.24Å; Q74-H78 PolarHBondContact O-N 3.04Å; H75-H78 PolarHBondContact O-N 2.84Å; H78-A80 VanDerWaalsContact C-N 3.3Å; H78-A80 PolarHBondContact O-N 3.43Å; H78-T81 PolarHBondContact O-N 3.31Å; H78-T81 PolarHBondContact O-OG1 3.23Å; H78-V82 PolarHBondContact O-N 3.14Å; H78-G83 PolarHBondContact O-N 3.41Å; H78-T85 PolarHBondContact CD2-OG1 3.08Å; H78-T85 PolarHBondContact NE2-OG1 3.21Å; H78-F86 AromaticContact CE1-CE2 3.76Å; H78-F86 AromaticContact NE2-CD2 3.92Å; H78-F86 AromaticContact NE2-CE2 3.76Å; H78-N89 PolarHBondContact CD2-ND2 2.93Å; H78-Y275 AromaticContact CE1-CE1 3.92Å
79	I	93.3	Very high	92.5	Very high	2 Å²	2	18 Å²	18	1%	0.01	9%	0.094	C	C	.	.	H	α-helix	trans	-63.3	-40.1	176.6	-62.9	158.5	0	0	0	110.2	H75 L77 T81 G83 Y84 N89 F92 P97 R101	H75-I79 WeakPolarHBondContact O-CB 3.37Å; H75-I79 VanDerWaalsContact O-CD1 3.32Å; H75-I79 WeakPolarHBondContact O-CD1 3.43Å; H75-I79 WeakPolarHBondContact O-CG1 3.27Å; H75-I79 PolarHBondContact O-N 3.13Å; L77-I79 PolarHBondContact O-N 2.91Å; I79-T81 VanDerWaalsContact C-N 3.29Å; I79-T81 PolarHBondContact O-N 3.48Å; I79-G83 WeakPolarHBondContact O-CA 3.38Å; I79-G83 PolarHBondContact O-N 3.35Å; I79-G83 VanDerWaalsContact O-N 3.11Å; I79-Y84 HydrophobicContact CD1-CD1 4.15Å; I79-Y84 HydrophobicContact CD1-CE1 3.61Å; I79-Y84 HydrophobicContact CG1-CD1 4.04Å; I79-Y84 HydrophobicContact CG1-CE1 3.91Å; I79-Y84 HydrophobicContact CG2-CD1 4.32Å; I79-Y84 HydrophobicContact CG2-CD2 3.94Å; I79-Y84 HydrophobicContact CG2-CE1 3.91Å; I79-Y84 HydrophobicContact CG2-CE2 3.5Å; I79-Y84 HydrophobicContact CG2-CG 4.34Å; I79-Y84 VanDerWaalsContact CG2-CZ 3.49Å; I79-N89 HydrophobicContact CD1-CB 4Å; I79-N89 WeakPolarHBondContact CD1-O 3.47Å; I79-N89 HydrophobicContact CG1-CB 3.93Å; I79-F92 HydrophobicContact CD1-CB 3.71Å; I79-P97 HydrophobicContact CB-CB 3.88Å; I79-P97 HydrophobicContact CB-CG 3.93Å; I79-P97 HydrophobicContact CD1-CG 4.41Å; I79-P97 HydrophobicContact CG2-CB 3.49Å; I79-P97 VanDerWaalsContact CG2-CB 3.49Å; I79-P97 HydrophobicContact CG2-CG 3.75Å; I79-R101 PolarHBondContact O-NH2 3.41Å
80	A	91	Very high	92.7	Very high	4 Å²	4	16.8 Å²	16.8	3%	0.033	9%	0.087	C	C	.	.	H	α-helix	trans	-62.9	-38.4	-179.6	0	0	0	0	0	112.2	F76 L77 H78 P97 I100 R101	F76-A80 WeakPolarHBondContact O-CB 3.43Å; F76-A80 PolarHBondContact O-N 3.43Å; L77-A80 PolarHBondContact O-N 3.13Å; H78-A80 VanDerWaalsContact C-N 3.3Å; H78-A80 PolarHBondContact O-N 3.43Å; A80-P97 HydrophobicContact CB-CB 4.2Å; A80-I100 HydrophobicContact CB-CB 3.79Å; A80-I100 HydrophobicContact CB-CD1 4.36Å; A80-I100 HydrophobicContact CB-CG2 3.6Å; A80-R101 PolarHBondContact O-NE 2.86Å
81	T	86.8	Confident	92.9	Very high	70 Å²	70	15.8 Å²	15.8	43%	0.429	9%	0.086	S	C	.	.	H	α-helix	trans	-93.1	-45.4	-169.9	51.9	0	0	0	0	113.4	M51 L77 H78 I79	M51-T81 HydrophobicContact CE-CG2 3.52Å; M51-T81 HydrophobicContact SD-CG2 3.78Å; L77-T81 WeakPolarHBondContact O-CB 3.41Å; L77-T81 WeakPolarHBondContact O-CG2 3.36Å; L77-T81 PolarHBondContact O-N 2.77Å; L77-T81 PolarHBondContact O-OG1 3.3Å; H78-T81 PolarHBondContact O-N 3.31Å; H78-T81 PolarHBondContact O-OG1 3.23Å; I79-T81 VanDerWaalsContact C-N 3.29Å; I79-T81 PolarHBondContact O-N 3.48Å
82	V	87.9	Confident	93	Very high	52 Å²	52	13.6 Å²	13.6	32%	0.315	8%	0.078	S	C	.	.	T	Hydrogen-bonded Turn	trans	-109.6	-33.8	-175.9	-170.5	0	0	0	0	111.3	H78 T85 L269 Y275	H78-V82 PolarHBondContact O-N 3.14Å; V82-T85 HydrophobicContact CB-CG2 4.41Å; V82-T85 HydrophobicContact CG1-CG2 3.64Å; V82-L269 HydrophobicContact CG1-CD1 4.38Å; V82-Y275 HydrophobicContact CG1-CE2 4.16Å; V82-Y275 WeakPolarHBondContact CG2-OH 3.42Å
83	G	91.4	Very high	93.1	Very high	9 Å²	9	12.7 Å²	12.7	9%	0.093	7%	0.073	C	C	.	.			trans	104.5	-165.6	-176.2	0	0	0	0	0	113.3	H78 I79 T85	H78-G83 PolarHBondContact O-N 3.41Å; I79-G83 WeakPolarHBondContact O-CA 3.38Å; I79-G83 PolarHBondContact O-N 3.35Å; I79-G83 VanDerWaalsContact O-N 3.11Å; G83-T85 PolarHBondContact O-N 3.08Å
84	Y	93.5	Very high	93.3	Very high	17 Å²	17	14.9 Å²	14.9	7%	0.067	9%	0.087	C	C	.	.	S	Bend	trans	-83.2	98.1	-179.8	-65.4	-87.1	0	0	0	110.1	I79 N89 A90 F92 P94 Y252 F255 I256	I79-Y84 HydrophobicContact CD1-CD1 4.15Å; I79-Y84 HydrophobicContact CD1-CE1 3.61Å; I79-Y84 HydrophobicContact CG1-CD1 4.04Å; I79-Y84 HydrophobicContact CG1-CE1 3.91Å; I79-Y84 HydrophobicContact CG2-CD1 4.32Å; I79-Y84 HydrophobicContact CG2-CD2 3.94Å; I79-Y84 HydrophobicContact CG2-CE1 3.91Å; I79-Y84 HydrophobicContact CG2-CE2 3.5Å; I79-Y84 HydrophobicContact CG2-CG 4.34Å; I79-Y84 VanDerWaalsContact CG2-CZ 3.49Å; Y84-N89 HydrophobicContact CD1-CB 4.09Å; Y84-N89 WeakPolarHBondContact CE1-O 3.48Å; Y84-A90 HydrophobicContact CD1-CB 4.47Å; Y84-F92 WeakPolarHBondContact CE1-O 3.47Å; Y84-F92 PolarHBondContact OH-O 3.35Å; Y84-P94 VanDerWaalsContact OH-CA 3.29Å; Y84-P94 WeakPolarHBondContact OH-CA 3.23Å; Y84-Y252 HydrophobicContact CE1-CE2 4.24Å; Y84-Y252 VanDerWaalsContact CE1-OH 3.32Å; Y84-Y252 WeakPolarHBondContact CE1-OH 3.26Å; Y84-Y252 HydrophobicContact CE2-CE2 4.36Å; Y84-Y252 AromaticContact CZ-CE2 3.78Å; Y84-Y252 WeakPolarHBondContact OH-CE2 3.28Å; Y84-Y252 PolarHBondContact OH-OH 2.96Å; Y84-F255 AromaticContact CD2-CE1 3.59Å; Y84-F255 HydrophobicContact CD2-CE1 3.59Å; Y84-F255 HydrophobicContact CD2-CZ 4.07Å; Y84-F255 AromaticContact CE2-CE1 3.74Å; Y84-F255 HydrophobicContact CE2-CE1 3.74Å; Y84-F255 HydrophobicContact CE2-CZ 4.45Å; Y84-F255 HydrophobicContact CG-CE1 4.43Å; Y84-I256 HydrophobicContact CD1-CD1 3.89Å; Y84-I256 HydrophobicContact CD2-CD1 4.33Å; Y84-I256 HydrophobicContact CE1-CD1 4.14Å; Y84-I256 HydrophobicContact CG-CD1 3.98Å
85	T	92.7	Very high	93.4	Very high	1 Å²	1	15.7 Å²	15.7	1%	0.006	9%	0.09	C	C	.	.			trans	-106.3	-51.5	-178.2	55.5	0	0	0	0	111.5	H78 V82 G83 L269 L287	H78-T85 PolarHBondContact CD2-OG1 3.08Å; H78-T85 PolarHBondContact NE2-OG1 3.21Å; V82-T85 HydrophobicContact CB-CG2 4.41Å; V82-T85 HydrophobicContact CG1-CG2 3.64Å; G83-T85 PolarHBondContact O-N 3.08Å; T85-L269 HydrophobicContact CG2-CD1 3.49Å; T85-L269 VanDerWaalsContact CG2-CD1 3.49Å; T85-L269 HydrophobicContact CG2-CD2 4.23Å; T85-L269 HydrophobicContact CG2-CG 4.41Å; T85-L287 PolarHBondContact O-N 3.17Å
86	F	94.1	Very high	93.3	Very high	0 Å²	0	15.2 Å²	15.2	0%	0	9%	0.089	C	C	.	.	B	Isolated β-bridge	trans	-91.8	143.3	177.5	-53.3	-78.3	0	0	0	110.7	F46 P49 H78 N88 N89 F260 Y275 Y278 A279 N285 L286	F46-F86 AromaticContact CE2-CD2 3.52Å; F46-F86 HydrophobicContact CE2-CD2 3.52Å; F46-F86 AromaticContact CE2-CE2 3.72Å; F46-F86 HydrophobicContact CE2-CE2 3.72Å; F46-F86 HydrophobicContact CE2-CG 4.2Å; F46-F86 AromaticContact CZ-CD2 3.77Å; F46-F86 HydrophobicContact CZ-CD2 3.77Å; F46-F86 AromaticContact CZ-CE2 3.91Å; F46-F86 HydrophobicContact CZ-CE2 3.91Å; P49-F86 HydrophobicContact CG-CE2 4.47Å; P49-F86 HydrophobicContact CG-CZ 4.18Å; H78-F86 AromaticContact CE1-CE2 3.76Å; H78-F86 AromaticContact NE2-CD2 3.92Å; H78-F86 AromaticContact NE2-CE2 3.76Å; F86-N88 VanDerWaalsContact C-N 3.32Å; F86-N88 WeakPolarHBondContact CB-OD1 3.22Å; F86-N88 PolarHBondContact O-N 3.06Å; F86-N89 VanDerWaalsContact O-CB 3.27Å; F86-N89 WeakPolarHBondContact O-CB 3.44Å; F86-N89 PolarHBondContact O-N 2.85Å; F86-N89 VanDerWaalsContact O-N 3.11Å; F86-F260 WeakPolarHBondContact O-CZ 3.37Å; F86-Y275 HydrophobicContact CE2-CD1 4.32Å; F86-Y275 AromaticContact CZ-CD1 3.96Å; F86-Y275 HydrophobicContact CZ-CD1 3.96Å; F86-Y275 HydrophobicContact CZ-CG 4.42Å; F86-Y278 AromaticContact CE1-CD1 3.86Å; F86-Y278 HydrophobicContact CE1-CD1 3.86Å; F86-Y278 HydrophobicContact CE2-CD1 4.38Å; F86-Y278 AromaticContact CZ-CD1 3.62Å; F86-Y278 HydrophobicContact CZ-CD1 3.62Å; F86-Y278 HydrophobicContact CZ-CE1 4.29Å; F86-A279 HydrophobicContact CD1-CB 4.23Å; F86-A279 HydrophobicContact CE1-CB 3.94Å; F86-N285 WeakPolarHBondContact CA-O 3.25Å; F86-L286 HydrophobicContact CD1-CD1 3.79Å; F86-L286 HydrophobicContact CE1-CD1 3.78Å; F86-L286 HydrophobicContact CZ-CD1 4.47Å
87	E	94.5	Very high	93.3	Very high	3 Å²	3	15.2 Å²	15.2	1%	0.014	9%	0.089	C	C	.	.	G	3₁₀ helix	trans	-58.9	-41.9	-178.3	178.2	-171.8	-147.7	0	0	112.5	N89 A90 F260 N285 L293 W295 I307 R310 Y311	E87-N89 PolarHBondContact O-N 3.42Å; E87-A90 WeakPolarHBondContact O-CB 3.26Å; E87-A90 PolarHBondContact O-N 3.18Å; E87-F260 HydrophobicContact CB-CE1 4.28Å; E87-N285 HydrophobicContact CB-CB 3.84Å; E87-N285 PolarHBondContact N-O 3.26Å; E87-N285 WeakPolarHBondContact OE2-CB 3.49Å; E87-N285 PolarHBondContact OE2-ND2 2.98Å; E87-L293 HydrophobicContact CB-CD2 4.06Å; E87-L293 VanDerWaalsContact CD-CD2 3.47Å; E87-L293 HydrophobicContact CG-CD2 3.86Å; E87-L293 WeakPolarHBondContact OE1-CD2 3.23Å; E87-W295 VanDerWaalsContact OE1-CD1 3.26Å; E87-W295 PolarHBondContact OE1-NE1 2.88Å; E87-I307 HydrophobicContact CG-CD1 3.97Å; E87-I307 HydrophobicContact CG-CG1 3.76Å; E87-I307 WeakPolarHBondContact O-CD1 3.37Å; E87-R310 IonicContact OE2-NE 3.7Å; E87-Y311 HydrophobicContact CB-CE2 4.29Å; E87-Y311 HydrophobicContact CG-CE2 4.01Å; E87-Y311 VanDerWaalsContact OE2-CE2 3.26Å; E87-Y311 WeakPolarHBondContact OE2-CE2 3.46Å; E87-Y311 VanDerWaalsContact OE2-CZ 3.31Å; E87-Y311 PolarHBondContact OE2-OH 3.45Å
88	N	94.8	Very high	93.4	Very high	3 Å²	3	15.4 Å²	15.4	2%	0.016	10%	0.099	C	C	.	.	G	3₁₀ helix	trans	-59.9	-26.9	178.1	59.9	-19	0	0	0	113.2	H75 F86 A90 A91 Y284 Y311 W312	H75-N88 PolarHBondContact CE1-ND2 3.37Å; F86-N88 VanDerWaalsContact C-N 3.32Å; F86-N88 WeakPolarHBondContact CB-OD1 3.22Å; F86-N88 PolarHBondContact O-N 3.06Å; N88-A90 PolarHBondContact O-N 3.2Å; N88-A91 PolarHBondContact O-N 3.46Å; N88-Y284 WeakPolarHBondContact ND2-CE1 3.23Å; N88-Y311 HydrophobicContact CB-CD1 4.19Å; N88-Y311 HydrophobicContact CB-CD2 3.79Å; N88-Y311 HydrophobicContact CB-CE1 4.33Å; N88-Y311 HydrophobicContact CB-CE2 3.92Å; N88-Y311 HydrophobicContact CB-CG 3.91Å; N88-W312 HydrophobicContact CB-CH2 4.28Å
89	N	95.3	Very high	93.3	Very high	0 Å²	0	17.1 Å²	17.1	0%	0	11%	0.107	C	C	.	.	G	3₁₀ helix	trans	-62.7	-26.1	174.7	-66.9	-18	0	0	0	112.3	H75 H78 I79 Y84 F86 E87 A91 F92	H75-N89 PolarHBondContact ND1-OD1 3.08Å; H78-N89 PolarHBondContact CD2-ND2 2.93Å; I79-N89 HydrophobicContact CD1-CB 4Å; I79-N89 WeakPolarHBondContact CD1-O 3.47Å; I79-N89 HydrophobicContact CG1-CB 3.93Å; Y84-N89 HydrophobicContact CD1-CB 4.09Å; Y84-N89 WeakPolarHBondContact CE1-O 3.48Å; F86-N89 VanDerWaalsContact O-CB 3.27Å; F86-N89 WeakPolarHBondContact O-CB 3.44Å; F86-N89 PolarHBondContact O-N 2.85Å; F86-N89 VanDerWaalsContact O-N 3.11Å; E87-N89 PolarHBondContact O-N 3.42Å; N89-A91 PolarHBondContact O-N 3.23Å; N89-F92 WeakPolarHBondContact O-CB 3.39Å; N89-F92 PolarHBondContact O-N 2.73Å
90	A	95.1	Very high	93	Very high	0 Å²	0	18.6 Å²	18.6	0%	0	12%	0.115	C	C	.	.	G	3₁₀ helix	trans	-73.6	-1.4	-179.3	0	0	0	0	0	114.2	Y84 E87 N88 F92 Y252 I256 F260 I307	Y84-A90 HydrophobicContact CD1-CB 4.47Å; E87-A90 WeakPolarHBondContact O-CB 3.26Å; E87-A90 PolarHBondContact O-N 3.18Å; N88-A90 PolarHBondContact O-N 3.2Å; A90-F92 VanDerWaalsContact C-N 3.28Å; A90-Y252 WeakPolarHBondContact CA-OH 3.41Å; A90-Y252 PolarHBondContact O-OH 3.12Å; A90-I256 HydrophobicContact CB-CD1 3.69Å; A90-I256 HydrophobicContact CB-CG1 4.01Å; A90-I256 HydrophobicContact CB-CG2 3.72Å; A90-F260 HydrophobicContact CB-CE2 4.38Å; A90-I307 HydrophobicContact CB-CD1 3.72Å
91	A	95	Very high	92.9	Very high	13 Å²	13	24 Å²	24	11%	0.107	13%	0.134	C	C	.	.	G	3₁₀ helix	trans	-73.2	-22	163.5	0	0	0	0	0	112.7	N88 N89 I307 W312	N88-A91 PolarHBondContact O-N 3.46Å; N89-A91 PolarHBondContact O-N 3.23Å; A91-I307 HydrophobicContact CB-CG2 4.06Å; A91-W312 HydrophobicContact CB-CH2 3.67Å; A91-W312 HydrophobicContact CB-CZ3 3.75Å
92	F	96.4	Very high	92.9	Very high	16 Å²	16	26.4 Å²	26.4	7%	0.07	14%	0.144	C	C	.	.	S	Bend	trans	-99.4	118.8	-172.8	-61.2	-84	0	0	0	111	D72 H75 F76 I79 Y84 N89 A90 Y252 W312	D72-F92 HydrophobicContact CB-CD1 4.45Å; D72-F92 HydrophobicContact CB-CE1 3.55Å; D72-F92 HydrophobicContact CB-CZ 4.07Å; H75-F92 HydrophobicContact CB-CD1 4.24Å; H75-F92 HydrophobicContact CB-CD2 3.44Å; H75-F92 VanDerWaalsContact CB-CD2 3.44Å; H75-F92 HydrophobicContact CB-CE1 4.31Å; H75-F92 HydrophobicContact CB-CE2 3.51Å; H75-F92 HydrophobicContact CB-CG 3.82Å; H75-F92 HydrophobicContact CB-CZ 3.95Å; H75-F92 AromaticContact CD2-CE2 3.22Å; H75-F92 WeakPolarHBondContact CD2-CE2 3.39Å; H75-F92 AromaticContact CD2-CZ 3.29Å; H75-F92 WeakPolarHBondContact CD2-CZ 3.29Å; H75-F92 AromaticContact CE1-CE2 3.9Å; H75-F92 AromaticContact CG-CD2 3.63Å; H75-F92 AromaticContact CG-CE2 3.19Å; H75-F92 AromaticContact CG-CZ 3.69Å; H75-F92 AromaticContact ND1-CE2 3.64Å; H75-F92 AromaticContact NE2-CE2 3.69Å; H75-F92 AromaticContact NE2-CZ 3.95Å; F76-F92 HydrophobicContact CD1-CB 4.21Å; F76-F92 HydrophobicContact CD2-CD1 4.39Å; F76-F92 HydrophobicContact CE1-CB 3.89Å; F76-F92 HydrophobicContact CE1-CD1 4.04Å; F76-F92 HydrophobicContact CE1-CG 4.43Å; F76-F92 AromaticContact CE2-CD1 3.83Å; F76-F92 HydrophobicContact CE2-CD1 3.83Å; F76-F92 HydrophobicContact CE2-CE1 4.36Å; F76-F92 HydrophobicContact CZ-CB 4.35Å; F76-F92 AromaticContact CZ-CD1 3.65Å; F76-F92 HydrophobicContact CZ-CD1 3.65Å; F76-F92 HydrophobicContact CZ-CG 4.46Å; I79-F92 HydrophobicContact CD1-CB 3.71Å; Y84-F92 WeakPolarHBondContact CE1-O 3.47Å; Y84-F92 PolarHBondContact OH-O 3.35Å; N89-F92 WeakPolarHBondContact O-CB 3.39Å; N89-F92 PolarHBondContact O-N 2.73Å; A90-F92 VanDerWaalsContact C-N 3.28Å; F92-Y252 PolarHBondContact O-OH 3.42Å; F92-W312 HydrophobicContact CE2-CH2 4Å; F92-W312 HydrophobicContact CE2-CZ2 4.03Å; F92-W312 HydrophobicContact CZ-CH2 4.42Å; F92-W312 HydrophobicContact CZ-CZ2 4.04Å
93	F	96.7	Very high	92.4	Very high	6 Å²	6	26.1 Å²	26.1	3%	0.026	14%	0.14	C	C	.	.			trans	-71.5	153.9	-169.9	-90	-121.6	0	0	0	113.2	F95 P97 V192 A193 A194 F249 Y252 Y304	F93-F95 PolarHBondContact O-N 3.41Å; F93-P97 VanDerWaalsContact O-CD 3.24Å; F93-P97 WeakPolarHBondContact O-CD 3.32Å; F93-V192 WeakPolarHBondContact CD1-O 3.06Å; F93-V192 WeakPolarHBondContact CE1-O 3.23Å; F93-A193 WeakPolarHBondContact CB-O 3.33Å; F93-A194 WeakPolarHBondContact CB-O 3.49Å; F93-F249 AromaticContact CE1-CD2 3.8Å; F93-F249 HydrophobicContact CE1-CD2 3.8Å; F93-F249 HydrophobicContact CE1-CE2 4.43Å; F93-F249 AromaticContact CZ-CD2 3.5Å; F93-F249 HydrophobicContact CZ-CD2 3.5Å; F93-F249 VanDerWaalsContact CZ-CD2 3.5Å; F93-F249 AromaticContact CZ-CE2 3.68Å; F93-F249 HydrophobicContact CZ-CE2 3.68Å; F93-Y252 HydrophobicContact CD1-CD1 4.08Å; F93-Y252 HydrophobicContact CD1-CE1 4.48Å; F93-Y252 HydrophobicContact CD2-CD1 4.16Å; F93-Y252 AromaticContact CD2-CE1 3.81Å; F93-Y252 HydrophobicContact CD2-CE1 3.81Å; F93-Y252 AromaticContact CE1-CD1 3.88Å; F93-Y252 HydrophobicContact CE1-CD1 3.88Å; F93-Y252 HydrophobicContact CE1-CE1 4.49Å; F93-Y252 AromaticContact CE2-CD1 3.95Å; F93-Y252 HydrophobicContact CE2-CD1 3.95Å; F93-Y252 AromaticContact CE2-CE1 3.8Å; F93-Y252 HydrophobicContact CE2-CE1 3.8Å; F93-Y252 HydrophobicContact CG-CD1 4.21Å; F93-Y252 HydrophobicContact CG-CE1 4.15Å; F93-Y252 AromaticContact CZ-CD1 3.79Å; F93-Y252 HydrophobicContact CZ-CD1 3.79Å; F93-Y252 HydrophobicContact CZ-CE1 4.14Å; F93-Y304 AromaticContact CE2-CD2 3.97Å; F93-Y304 HydrophobicContact CE2-CD2 3.97Å; F93-Y304 AromaticContact CE2-CE2 3.77Å; F93-Y304 HydrophobicContact CE2-CE2 3.77Å
94	P	96.3	Very high	91.7	Very high	46 Å²	46	28.7 Å²	28.7	30%	0.299	16%	0.157	S	C	.	.	S	Bend	trans	-80.3	-13.1	-161.4	32.3	-36.5	0	0	0	114.3	Y84 G98 Y252	Y84-P94 VanDerWaalsContact OH-CA 3.29Å; Y84-P94 WeakPolarHBondContact OH-CA 3.23Å; P94-G98 WeakPolarHBondContact O-CA 3.44Å; P94-G98 PolarHBondContact O-N 2.82Å; P94-Y252 HydrophobicContact CB-CD2 4.22Å; P94-Y252 HydrophobicContact CB-CE2 4.25Å; P94-Y252 VanDerWaalsContact CD-CD2 3.49Å; P94-Y252 HydrophobicContact CG-CD2 3.61Å; P94-Y252 HydrophobicContact CG-CE2 4.04Å; P94-Y252 HydrophobicContact CG-CG 4.19Å
95	F	95.5	Very high	90.5	Very high	40 Å²	40	32.2 Å²	32.2	18%	0.175	18%	0.184	C	C	.	.	H	α-helix	trans	-65.7	-51.4	-171	-171.3	-166.2	0	0	0	112.2	F93 G98 M99 W167 L190 A193 A194	F93-F95 PolarHBondContact O-N 3.41Å; F95-G98 PolarHBondContact O-N 3.3Å; F95-M99 HydrophobicContact CD2-CG 3.75Å; F95-M99 HydrophobicContact CD2-SD 3.83Å; F95-M99 HydrophobicContact CE2-CE 4.3Å; F95-M99 HydrophobicContact CE2-CG 3.7Å; F95-M99 HydrophobicContact CE2-SD 3.41Å; F95-M99 WeakPolarHBondContact CE2-SD 3.37Å; F95-M99 HydrophobicContact CZ-SD 3.88Å; F95-M99 VanDerWaalsContact O-CG 3.27Å; F95-M99 WeakPolarHBondContact O-CG 3.3Å; F95-M99 PolarHBondContact O-N 2.75Å; F95-W167 AromaticContact CE1-CD1 3.6Å; F95-W167 AromaticContact CE1-NE1 3.31Å; F95-W167 VanDerWaalsContact CE1-NE1 3.31Å; F95-W167 AromaticContact CZ-NE1 3.66Å; F95-L190 WeakPolarHBondContact CD1-O 3.4Å; F95-L190 HydrophobicContact CE1-CB 4.03Å; F95-L190 HydrophobicContact CE1-CD2 4.18Å; F95-L190 HydrophobicContact CZ-CD2 4.07Å; F95-A193 VanDerWaalsContact CB-C 3.45Å; F95-A193 HydrophobicContact CB-CB 3.96Å; F95-A193 WeakPolarHBondContact CB-O 3.49Å; F95-A193 HydrophobicContact CD1-CB 4.06Å; F95-A193 HydrophobicContact CG-CB 4.2Å; F95-A193 PolarHBondContact N-O 2.91Å; F95-A194 HydrophobicContact CD1-CB 4.03Å
96	L	93.3	Very high	88.9	Confident	3 Å²	3	35.8 Å²	35.8	2%	0.016	21%	0.213	C	C	.	.	H	α-helix	trans	-61.5	-52.4	178.9	172.5	62.9	0	0	0	112.2	F76 G98 M99 I100 F114 I158 Y159 L163	F76-L96 HydrophobicContact CB-CD2 4.26Å; F76-L96 HydrophobicContact CD1-CB 4.31Å; F76-L96 HydrophobicContact CD1-CD2 3.92Å; F76-L96 HydrophobicContact CD1-CG 4.34Å; F76-L96 HydrophobicContact CD2-CD2 4.13Å; F76-L96 HydrophobicContact CE1-CB 4.43Å; F76-L96 HydrophobicContact CE1-CD2 4.22Å; F76-L96 HydrophobicContact CE2-CD2 4.42Å; F76-L96 HydrophobicContact CG-CD2 3.86Å; F76-L96 HydrophobicContact CZ-CD2 4.45Å; L96-G98 VanDerWaalsContact C-N 3.29Å; L96-G98 PolarHBondContact O-N 3.4Å; L96-M99 PolarHBondContact O-N 3.41Å; L96-M99 VanDerWaalsContact O-N 3.16Å; L96-I100 HydrophobicContact CD1-CD1 3.97Å; L96-I100 HydrophobicContact CD1-CG1 4.09Å; L96-I100 HydrophobicContact CG-CD1 3.97Å; L96-I100 WeakPolarHBondContact O-CG1 3.49Å; L96-I100 PolarHBondContact O-N 3Å; L96-F114 HydrophobicContact CD1-CE1 3.6Å; L96-F114 HydrophobicContact CD1-CZ 4.03Å; L96-F114 HydrophobicContact CD2-CE1 4.33Å; L96-I158 HydrophobicContact CD2-CG2 4.35Å; L96-Y159 VanDerWaalsContact CD2-C 3.44Å; L96-L163 HydrophobicContact CB-CD1 3.99Å; L96-L163 HydrophobicContact CD1-CD1 3.77Å; L96-L163 HydrophobicContact CG-CD1 4.47Å
97	P	93	Very high	86.8	Confident	2 Å²	2	40.5 Å²	40.5	1%	0.013	24%	0.236	C	C	.	.	H	α-helix	trans	-58.2	-39.1	176.4	-26.9	36.2	0	0	0	113.6	F76 I79 A80 F93 M99 I100 R101	F76-P97 HydrophobicContact CB-CG 4.44Å; F76-P97 HydrophobicContact CD1-CG 3.73Å; I79-P97 HydrophobicContact CB-CB 3.88Å; I79-P97 HydrophobicContact CB-CG 3.93Å; I79-P97 HydrophobicContact CD1-CG 4.41Å; I79-P97 HydrophobicContact CG2-CB 3.49Å; I79-P97 VanDerWaalsContact CG2-CB 3.49Å; I79-P97 HydrophobicContact CG2-CG 3.75Å; A80-P97 HydrophobicContact CB-CB 4.2Å; F93-P97 VanDerWaalsContact O-CD 3.24Å; F93-P97 WeakPolarHBondContact O-CD 3.32Å; P97-M99 VanDerWaalsContact C-N 3.35Å; P97-I100 PolarHBondContact O-N 3.25Å; P97-R101 WeakPolarHBondContact O-CB 3.27Å; P97-R101 PolarHBondContact O-N 3.39Å
98	G	93.5	Very high	84.7	Confident	37 Å²	37	48.1 Å²	48.1	38%	0.381	27%	0.27	S	S	.	.	H	α-helix	trans	-63.2	-40.5	177.2	0	0	0	0	0	112.2	P94 F95 L96 R101 L102	P94-G98 WeakPolarHBondContact O-CA 3.44Å; P94-G98 PolarHBondContact O-N 2.82Å; F95-G98 PolarHBondContact O-N 3.3Å; L96-G98 VanDerWaalsContact C-N 3.29Å; L96-G98 PolarHBondContact O-N 3.4Å; G98-R101 PolarHBondContact O-N 2.83Å; G98-L102 WeakPolarHBondContact O-CB 3.48Å; G98-L102 PolarHBondContact O-N 2.92Å
99	M	90.2	Very high	82.5	Confident	36 Å²	36	49.9 Å²	49.9	18%	0.177	28%	0.281	C	S	.	.	H	α-helix	trans	-65.4	-45.1	173.8	-68.2	-171.8	90.3	0	0	111.8	F95 L96 P97 R101 L102 L103 F113 L163	F95-M99 HydrophobicContact CD2-CG 3.75Å; F95-M99 HydrophobicContact CD2-SD 3.83Å; F95-M99 HydrophobicContact CE2-CE 4.3Å; F95-M99 HydrophobicContact CE2-CG 3.7Å; F95-M99 HydrophobicContact CE2-SD 3.41Å; F95-M99 WeakPolarHBondContact CE2-SD 3.37Å; F95-M99 HydrophobicContact CZ-SD 3.88Å; F95-M99 VanDerWaalsContact O-CG 3.27Å; F95-M99 WeakPolarHBondContact O-CG 3.3Å; F95-M99 PolarHBondContact O-N 2.75Å; L96-M99 PolarHBondContact O-N 3.41Å; L96-M99 VanDerWaalsContact O-N 3.16Å; P97-M99 VanDerWaalsContact C-N 3.35Å; M99-R101 VanDerWaalsContact C-N 3.29Å; M99-R101 PolarHBondContact O-N 3.36Å; M99-L102 PolarHBondContact O-N 3.34Å; M99-L103 WeakPolarHBondContact O-CB 3.19Å; M99-L103 WeakPolarHBondContact O-CD1 3.39Å; M99-L103 VanDerWaalsContact O-CG 3.26Å; M99-L103 WeakPolarHBondContact O-CG 3.41Å; M99-L103 PolarHBondContact O-N 2.72Å; M99-F113 HydrophobicContact CE-CD1 4.07Å; M99-F113 HydrophobicContact CE-CE1 3.08Å; M99-F113 HydrophobicContact CE-CE2 4.05Å; M99-F113 HydrophobicContact CE-CZ 3.08Å; M99-F113 HydrophobicContact SD-CE1 3.84Å; M99-F113 HydrophobicContact SD-CZ 4.4Å; M99-L163 HydrophobicContact SD-CD1 3.87Å; M99-L163 HydrophobicContact SD-CD2 4.13Å
100	I	86.9	Confident	80.3	Confident	33 Å²	33	57.8 Å²	57.8	17%	0.169	31%	0.311	C	S	.	.	H	α-helix	trans	-57.1	-46.9	176.6	-64.8	167	0	0	0	109.8	A80 L96 P97 L103 S104 F114 I158	A80-I100 HydrophobicContact CB-CB 3.79Å; A80-I100 HydrophobicContact CB-CD1 4.36Å; A80-I100 HydrophobicContact CB-CG2 3.6Å; L96-I100 HydrophobicContact CD1-CD1 3.97Å; L96-I100 HydrophobicContact CD1-CG1 4.09Å; L96-I100 HydrophobicContact CG-CD1 3.97Å; L96-I100 WeakPolarHBondContact O-CG1 3.49Å; L96-I100 PolarHBondContact O-N 3Å; P97-I100 PolarHBondContact O-N 3.25Å; I100-L103 PolarHBondContact O-N 3.22Å; I100-S104 WeakPolarHBondContact O-CB 3.42Å; I100-S104 PolarHBondContact O-N 2.99Å; I100-S104 PolarHBondContact O-OG 2.78Å; I100-F114 HydrophobicContact CD1-CZ 3.94Å; I100-F114 HydrophobicContact CG1-CZ 4.06Å; I100-I158 HydrophobicContact CD1-CG2 3.83Å
101	R	87.5	Confident	78.3	Confident	117 Å²	117	60.7 Å²	60.7	44%	0.442	33%	0.326	S	S	.	.	H	α-helix	trans	-63.8	-45.5	-179.9	-170.8	-176.5	-61.5	179	0.5	113	I79 A80 P97 G98 M99 L103 S104 S105	I79-R101 PolarHBondContact O-NH2 3.41Å; A80-R101 PolarHBondContact O-NE 2.86Å; P97-R101 WeakPolarHBondContact O-CB 3.27Å; P97-R101 PolarHBondContact O-N 3.39Å; G98-R101 PolarHBondContact O-N 2.83Å; M99-R101 VanDerWaalsContact C-N 3.29Å; M99-R101 PolarHBondContact O-N 3.36Å; R101-L103 VanDerWaalsContact C-N 3.32Å; R101-L103 PolarHBondContact O-N 2.89Å; R101-S104 WeakPolarHBondContact CA-OG 3.38Å; R101-S104 PolarHBondContact O-OG 2.88Å; R101-S105 PolarHBondContact O-N 3.45Å; R101-S105 VanDerWaalsContact O-N 3.16Å
102	L	86.7	Confident	76.1	Confident	121 Å²	121	62.1 Å²	62.1	63%	0.634	34%	0.336	S	S	*	.	H	α-helix	trans	-61.3	-44.7	177.9	-178.1	65.1	0	0	0	110.5	G98 M99 S105 A106	G98-L102 WeakPolarHBondContact O-CB 3.48Å; G98-L102 PolarHBondContact O-N 2.92Å; M99-L102 PolarHBondContact O-N 3.34Å; L102-S105 PolarHBondContact O-N 3.28Å; L102-S105 PolarHBondContact O-OG 2.97Å; L102-A106 PolarHBondContact O-N 3.48Å; L102-A106 VanDerWaalsContact O-N 3.15Å
103	L	78.1	Confident	73.8	Confident	46 Å²	46	64.1 Å²	64.1	24%	0.241	34%	0.344	C	S	.	.	H	α-helix	trans	-73.5	-37.2	-178.6	-68.7	164.9	0	0	0	112.7	M99 I100 R101 S105 A106 M107 F113	M99-L103 WeakPolarHBondContact O-CB 3.19Å; M99-L103 WeakPolarHBondContact O-CD1 3.39Å; M99-L103 VanDerWaalsContact O-CG 3.26Å; M99-L103 WeakPolarHBondContact O-CG 3.41Å; M99-L103 PolarHBondContact O-N 2.72Å; I100-L103 PolarHBondContact O-N 3.22Å; R101-L103 VanDerWaalsContact C-N 3.32Å; R101-L103 PolarHBondContact O-N 2.89Å; L103-S105 PolarHBondContact O-N 3.15Å; L103-A106 PolarHBondContact O-N 3.41Å; L103-A106 VanDerWaalsContact O-N 3.11Å; L103-M107 CarbonylContact O-C 3.58Å; L103-M107 WeakPolarHBondContact O-CA 3.41Å; L103-M107 PolarHBondContact O-N 3.34Å; L103-F113 HydrophobicContact CD1-CB 3.62Å; L103-F113 HydrophobicContact CD1-CD1 4.13Å; L103-F113 HydrophobicContact CD1-CD2 3.26Å; L103-F113 HydrophobicContact CD1-CE2 3.97Å; L103-F113 HydrophobicContact CD1-CG 3.36Å; L103-F113 HydrophobicContact CD2-CD2 4.28Å; L103-F113 HydrophobicContact CG-CD2 4.4Å
104	S	76	Confident	71.7	Confident	62 Å²	62	64.9 Å²	64.9	43%	0.434	35%	0.348	S	S	.	.	H	α-helix	trans	-63.3	-29.8	175	64.8	0	0	0	0	111.7	I100 R101 K108	I100-S104 WeakPolarHBondContact O-CB 3.42Å; I100-S104 PolarHBondContact O-N 2.99Å; I100-S104 PolarHBondContact O-OG 2.78Å; R101-S104 WeakPolarHBondContact CA-OG 3.38Å; R101-S104 PolarHBondContact O-OG 2.88Å; S104-K108 WeakPolarHBondContact O-CG 3.5Å
105	S	68.3	Low	69.8	Low	91 Å²	91	65.1 Å²	65.1	64%	0.636	35%	0.345	S	S	*	.	H	α-helix	trans	-74.5	-33.9	174.3	77	0	0	0	0	112.7	R101 L102 L103	R101-S105 PolarHBondContact O-N 3.45Å; R101-S105 VanDerWaalsContact O-N 3.16Å; L102-S105 PolarHBondContact O-N 3.28Å; L102-S105 PolarHBondContact O-OG 2.97Å; L103-S105 PolarHBondContact O-N 3.15Å
106	A	59	Low	68	Low	76 Å²	76	66.2 Å²	66.2	63%	0.628	35%	0.352	S	S	*	.	H	α-helix	trans	-88.6	-28.2	-178.3	0	0	0	0	0	114.1	L102 L103	L102-A106 PolarHBondContact O-N 3.48Å; L102-A106 VanDerWaalsContact O-N 3.15Å; L103-A106 PolarHBondContact O-N 3.41Å; L103-A106 VanDerWaalsContact O-N 3.11Å
107	M	50.7	Low	66.8	Low	99 Å²	99	66.2 Å²	66.2	49%	0.488	35%	0.352	S	S	.	.	S	Bend	trans	-148.9	80	-169.2	-63.9	-173	74.7	0	0	110.2	L103 P109 W110	L103-M107 CarbonylContact O-C 3.58Å; L103-M107 WeakPolarHBondContact O-CA 3.41Å; L103-M107 PolarHBondContact O-N 3.34Å; M107-P109 WeakPolarHBondContact O-CA 3.4Å; M107-W110 HydrophobicContact CE-CB 4.42Å; M107-W110 HydrophobicContact CE-CG 4.07Å; M107-W110 PolarHBondContact O-N 3.46Å
108	K	49.8	Very low	66	Low	163 Å²	163	66.2 Å²	66.2	71%	0.709	35%	0.352	S	S	*	.	T	Hydrogen-bonded Turn	trans	-72.7	123.4	167	-67.8	-176.2	177.3	-175.5	0	109.9	S104	S104-K108 WeakPolarHBondContact O-CG 3.5Å
109	P	50.1	Low	65.3	Low	41 Å²	41	67.5 Å²	67.5	27%	0.266	35%	0.346	S	S	.	.	T	Hydrogen-bonded Turn	cis	-111.6	113.6	-28.2	31.4	-13.7	0	0	0	110.1	A57 V61 M107	A57-P109 HydrophobicContact CB-CG 3.51Å; V61-P109 HydrophobicContact CG2-CB 4.38Å; V61-P109 HydrophobicContact CG2-CG 4.25Å; M107-P109 WeakPolarHBondContact O-CA 3.4Å
110	W	49.1	Very low	65	Low	165 Å²	165	68.6 Å²	68.6	63%	0.625	35%	0.351	S	S	*	.			trans	-123.1	99.9	171.6	-65.9	88	0	0	0	110.4	M107 S112	M107-W110 HydrophobicContact CE-CB 4.42Å; M107-W110 HydrophobicContact CE-CG 4.07Å; M107-W110 PolarHBondContact O-N 3.46Å; W110-S112 PolarHBondContact O-N 2.71Å
111	I	53	Low	64.9	Low	61 Å²	61	67 Å²	67	31%	0.313	34%	0.343	S	S	.	.	T	Hydrogen-bonded Turn	trans	-66.8	13.6	163.2	-60.1	-168.3	0	0	0	110.8	V61 F113 F114	V61-I111 HydrophobicContact CG1-CD1 3.21Å; V61-I111 HydrophobicContact CG1-CG1 3.89Å; I111-F113 PolarHBondContact O-N 3.01Å; I111-F114 HydrophobicContact CG2-CD2 3.53Å; I111-F114 HydrophobicContact CG2-CE2 3.94Å
112	S	48.2	Very low	64.9	Low	44 Å²	44	61.5 Å²	61.5	31%	0.308	32%	0.322	S	S	.	.	H	α-helix	trans	-60.5	-15.4	177.6	-56.2	0	0	0	0	114	W110 I116	W110-S112 PolarHBondContact O-N 2.71Å; S112-I116 WeakPolarHBondContact O-CG1 3.18Å
113	F	48.1	Very low	64.9	Low	57 Å²	57	56.8 Å²	56.8	25%	0.25	30%	0.297	C	S	.	.	H	α-helix	trans	-72.6	-34.3	-175.2	-152.2	-91.9	0	0	0	114.4	M99 L103 I111 Q115 I116 S117 L163	M99-F113 HydrophobicContact CE-CD1 4.07Å; M99-F113 HydrophobicContact CE-CE1 3.08Å; M99-F113 HydrophobicContact CE-CE2 4.05Å; M99-F113 HydrophobicContact CE-CZ 3.08Å; M99-F113 HydrophobicContact SD-CE1 3.84Å; M99-F113 HydrophobicContact SD-CZ 4.4Å; L103-F113 HydrophobicContact CD1-CB 3.62Å; L103-F113 HydrophobicContact CD1-CD1 4.13Å; L103-F113 HydrophobicContact CD1-CD2 3.26Å; L103-F113 HydrophobicContact CD1-CE2 3.97Å; L103-F113 HydrophobicContact CD1-CG 3.36Å; L103-F113 HydrophobicContact CD2-CD2 4.28Å; L103-F113 HydrophobicContact CG-CD2 4.4Å; I111-F113 PolarHBondContact O-N 3.01Å; F113-Q115 VanDerWaalsContact C-N 3.26Å; F113-Q115 PolarHBondContact O-N 3.22Å; F113-I116 HydrophobicContact CD2-CD1 4.17Å; F113-I116 HydrophobicContact CE2-CD1 4.5Å; F113-I116 PolarHBondContact O-N 3.03Å; F113-S117 PolarHBondContact O-N 2.94Å; F113-L163 HydrophobicContact CE1-CD2 4.22Å
114	F	53.5	Low	65.5	Low	23 Å²	23	55.9 Å²	55.9	10%	0.101	29%	0.291	C	S	.	.	H	α-helix	trans	-60.8	-40.3	-179.7	-65.7	-79.9	0	0	0	111.2	L96 I100 I111 I116 S117 I158	L96-F114 HydrophobicContact CD1-CE1 3.6Å; L96-F114 HydrophobicContact CD1-CZ 4.03Å; L96-F114 HydrophobicContact CD2-CE1 4.33Å; I100-F114 HydrophobicContact CD1-CZ 3.94Å; I100-F114 HydrophobicContact CG1-CZ 4.06Å; I111-F114 HydrophobicContact CG2-CD2 3.53Å; I111-F114 HydrophobicContact CG2-CE2 3.94Å; F114-I116 VanDerWaalsContact C-N 3.28Å; F114-I116 PolarHBondContact O-N 3.36Å; F114-S117 PolarHBondContact O-N 3.43Å; F114-S117 PolarHBondContact O-OG 3.43Å; F114-I158 HydrophobicContact CE1-CB 4.06Å; F114-I158 HydrophobicContact CE1-CG1 4.14Å; F114-I158 HydrophobicContact CE1-CG2 3.94Å; F114-I158 HydrophobicContact CE2-CG1 4.1Å; F114-I158 HydrophobicContact CZ-CB 4.04Å; F114-I158 HydrophobicContact CZ-CG1 3.81Å; F114-I158 HydrophobicContact CZ-CG2 3.67Å
115	Q	55.1	Low	66.2	Low	50 Å²	50	52.9 Å²	52.9	23%	0.234	27%	0.27	C	S	.	.	H	α-helix	trans	-64.5	-33.4	175.5	-64.9	165.3	69.6	0	0	112.6	W28 F113 S117 D118 Y119	W28-Q115 HydrophobicContact CH2-CG 3.94Å; W28-Q115 VanDerWaalsContact CH2-OE1 3.24Å; W28-Q115 HydrophobicContact CZ2-CG 3.31Å; F113-Q115 VanDerWaalsContact C-N 3.26Å; F113-Q115 PolarHBondContact O-N 3.22Å; Q115-S117 VanDerWaalsContact C-N 3.25Å; Q115-S117 PolarHBondContact O-N 2.85Å; Q115-D118 PolarHBondContact O-N 3.15Å; Q115-Y119 WeakPolarHBondContact O-CD1 3.28Å; Q115-Y119 PolarHBondContact O-N 2.96Å
116	I	57.5	Low	67.3	Low	64 Å²	64	48.7 Å²	48.7	33%	0.328	24%	0.241	S	C	.	.	H	α-helix	trans	-65.4	-37.1	-177.2	-60.9	167.3	0	0	0	110.8	S112 F113 F114 Y119 Q120	S112-I116 WeakPolarHBondContact O-CG1 3.18Å; F113-I116 HydrophobicContact CD2-CD1 4.17Å; F113-I116 HydrophobicContact CE2-CD1 4.5Å; F113-I116 PolarHBondContact O-N 3.03Å; F114-I116 VanDerWaalsContact C-N 3.28Å; F114-I116 PolarHBondContact O-N 3.36Å; I116-Y119 HydrophobicContact CB-CE1 3.8Å; I116-Y119 HydrophobicContact CG1-CE1 3.94Å; I116-Y119 HydrophobicContact CG2-CE1 3.72Å; I116-Y119 VanDerWaalsContact CG2-OH 3.31Å; I116-Y119 WeakPolarHBondContact CG2-OH 3.24Å; I116-Y119 WeakPolarHBondContact O-CD1 3.49Å; I116-Y119 WeakPolarHBondContact O-CE1 3.11Å; I116-Q120 VanDerWaalsContact O-CG 3.27Å; I116-Q120 WeakPolarHBondContact O-CG 2.96Å; I116-Q120 PolarHBondContact O-N 2.86Å
117	S	69	Low	68.8	Low	3 Å²	3	49.6 Å²	49.6	2%	0.021	23%	0.228	C	C	.	.	H	α-helix	trans	-65.8	-43.2	178.3	70	0	0	0	0	112.9	F113 F114 Q115 Q120 L121 S162	F113-S117 PolarHBondContact O-N 2.94Å; F114-S117 PolarHBondContact O-N 3.43Å; F114-S117 PolarHBondContact O-OG 3.43Å; Q115-S117 VanDerWaalsContact C-N 3.25Å; Q115-S117 PolarHBondContact O-N 2.85Å; S117-Q120 PolarHBondContact O-N 3.11Å; S117-L121 WeakPolarHBondContact O-CB 3.42Å; S117-L121 PolarHBondContact O-N 3.04Å; S117-S162 VanDerWaalsContact OG-CB 3.32Å; S117-S162 WeakPolarHBondContact OG-CB 3.3Å; S117-S162 PolarHBondContact OG-OG 3.01Å; S117-S162 VanDerWaalsContact OG-OG 3.11Å
118	D	76.1	Confident	70.6	Confident	2 Å²	2	45.2 Å²	45.2	1%	0.011	21%	0.206	C	C	.	.	H	α-helix	trans	-71	-42.5	-173.6	-167	63.2	0	0	0	112.9	Q115 Q120 L121 G122 H146 H156	Q115-D118 PolarHBondContact O-N 3.15Å; D118-Q120 VanDerWaalsContact C-N 3.34Å; D118-Q120 PolarHBondContact O-N 3.02Å; D118-L121 WeakPolarHBondContact O-CB 3.41Å; D118-L121 PolarHBondContact O-N 3.23Å; D118-G122 PolarHBondContact O-N 3.48Å; D118-H146 IonicContact OD1-CE1 3.62Å; D118-H146 IonicContact OD1-NE2 2.66Å; D118-H146 PolarHBondContact OD1-NE2 3.13Å; D118-H156 IonicContact OD2-NE2 2.7Å
119	Y	78.3	Confident	72.6	Confident	63 Å²	63	37.4 Å²	37.4	25%	0.247	17%	0.172	C	C	.	.	H	α-helix	trans	-67.1	-37.9	177.5	82	-109	0	0	0	111.7	L17 L20 Q115 I116 L121 G122 I123	L17-Y119 HydrophobicContact CD1-CD2 4.25Å; L17-Y119 HydrophobicContact CD1-CG 4.46Å; L20-Y119 WeakPolarHBondContact CD1-O 3.47Å; Q115-Y119 WeakPolarHBondContact O-CD1 3.28Å; Q115-Y119 PolarHBondContact O-N 2.96Å; I116-Y119 HydrophobicContact CB-CE1 3.8Å; I116-Y119 HydrophobicContact CG1-CE1 3.94Å; I116-Y119 HydrophobicContact CG2-CE1 3.72Å; I116-Y119 VanDerWaalsContact CG2-OH 3.31Å; I116-Y119 WeakPolarHBondContact CG2-OH 3.24Å; I116-Y119 WeakPolarHBondContact O-CD1 3.49Å; I116-Y119 WeakPolarHBondContact O-CE1 3.11Å; Y119-L121 VanDerWaalsContact C-N 3.32Å; Y119-G122 PolarHBondContact O-N 3.23Å; Y119-I123 HydrophobicContact CD2-CD1 4.11Å; Y119-I123 WeakPolarHBondContact O-CG1 3.36Å; Y119-I123 PolarHBondContact O-N 3.38Å
120	Q	83.5	Confident	74.4	Confident	60 Å²	60	36.9 Å²	36.9	28%	0.28	17%	0.167	S	C	.	.	H	α-helix	trans	-66.5	-39.7	175.1	-69	-68.8	-4.2	0	0	110.5	I116 S117 D118 G122 I123 F124 L166	I116-Q120 VanDerWaalsContact O-CG 3.27Å; I116-Q120 WeakPolarHBondContact O-CG 2.96Å; I116-Q120 PolarHBondContact O-N 2.86Å; S117-Q120 PolarHBondContact O-N 3.11Å; D118-Q120 VanDerWaalsContact C-N 3.34Å; D118-Q120 PolarHBondContact O-N 3.02Å; Q120-G122 PolarHBondContact O-N 2.98Å; Q120-I123 WeakPolarHBondContact O-CB 3.37Å; Q120-I123 PolarHBondContact O-N 3.02Å; Q120-F124 VanDerWaalsContact O-CD2 3.26Å; Q120-F124 WeakPolarHBondContact O-CD2 3.4Å; Q120-F124 PolarHBondContact O-N 2.95Å; Q120-L166 HydrophobicContact CB-CD1 3.57Å; Q120-L166 HydrophobicContact CB-CD2 4.29Å
121	L	86.4	Confident	76.2	Confident	0 Å²	0	31.1 Å²	31.1	0%	0	15%	0.147	C	C	.	.	H	α-helix	trans	-56.3	-50.4	175.7	168.1	60.8	0	0	0	110.7	S117 D118 Y119 I123 F124 L125 H146 F155 A165 L166 Y169	S117-L121 WeakPolarHBondContact O-CB 3.42Å; S117-L121 PolarHBondContact O-N 3.04Å; D118-L121 WeakPolarHBondContact O-CB 3.41Å; D118-L121 PolarHBondContact O-N 3.23Å; Y119-L121 VanDerWaalsContact C-N 3.32Å; L121-I123 VanDerWaalsContact C-N 3.29Å; L121-I123 PolarHBondContact O-N 3.02Å; L121-F124 PolarHBondContact O-N 3.29Å; L121-F124 VanDerWaalsContact O-N 3.16Å; L121-L125 WeakPolarHBondContact O-CB 3.34Å; L121-L125 PolarHBondContact O-N 2.87Å; L121-H146 VanDerWaalsContact CD2-CE1 3.47Å; L121-H146 WeakPolarHBondContact CD2-CE1 3.48Å; L121-F155 HydrophobicContact CD2-CD1 3.89Å; L121-F155 HydrophobicContact CD2-CE1 3.91Å; L121-A165 HydrophobicContact CD1-CB 3.54Å; L121-A165 HydrophobicContact CD2-CB 3.85Å; L121-A165 HydrophobicContact CG-CB 4.36Å; L121-L166 HydrophobicContact CB-CB 4.37Å; L121-Y169 HydrophobicContact CD1-CD2 3.36Å; L121-Y169 HydrophobicContact CD1-CE2 3.57Å; L121-Y169 HydrophobicContact CD1-CG 4.28Å
122	G	86.6	Confident	77.8	Confident	0 Å²	0	28.3 Å²	28.3	0%	0	13%	0.132	C	C	.	.	H	α-helix	trans	-59.2	-37	176.4	0	0	0	0	0	113.8	D118 Y119 Q120 Y126	D118-G122 PolarHBondContact O-N 3.48Å; Y119-G122 PolarHBondContact O-N 3.23Å; Q120-G122 PolarHBondContact O-N 2.98Å; G122-Y126 WeakPolarHBondContact O-CB 3.41Å; G122-Y126 PolarHBondContact O-N 3.2Å
123	I	87.2	Confident	79.6	Confident	23 Å²	23	26.7 Å²	26.7	12%	0.118	12%	0.12	C	C	.	.	H	α-helix	trans	-66.4	-43.6	175.2	-67.9	167.1	0	0	0	111.3	Y119 Q120 L121 Y126 R127	Y119-I123 HydrophobicContact CD2-CD1 4.11Å; Y119-I123 WeakPolarHBondContact O-CG1 3.36Å; Y119-I123 PolarHBondContact O-N 3.38Å; Q120-I123 WeakPolarHBondContact O-CB 3.37Å; Q120-I123 PolarHBondContact O-N 3.02Å; L121-I123 VanDerWaalsContact C-N 3.29Å; L121-I123 PolarHBondContact O-N 3.02Å; I123-Y126 PolarHBondContact O-N 3.32Å; I123-R127 WeakPolarHBondContact O-CG 3.2Å; I123-R127 PolarHBondContact O-N 3.06Å; I123-R127 VanDerWaalsContact O-N 3.09Å
124	F	90.1	Very high	81.3	Confident	26 Å²	26	25.7 Å²	25.7	11%	0.114	13%	0.126	C	C	.	.	H	α-helix	trans	-69	-39.3	177	-79.9	-71.8	0	0	0	112	Q120 L121 Y126 R127 V128 L166 A170 D173	Q120-F124 VanDerWaalsContact O-CD2 3.26Å; Q120-F124 WeakPolarHBondContact O-CD2 3.4Å; Q120-F124 PolarHBondContact O-N 2.95Å; L121-F124 PolarHBondContact O-N 3.29Å; L121-F124 VanDerWaalsContact O-N 3.16Å; F124-Y126 VanDerWaalsContact C-N 3.32Å; F124-Y126 PolarHBondContact O-N 3.41Å; F124-R127 PolarHBondContact O-N 2.69Å; F124-V128 WeakPolarHBondContact O-CG2 3.37Å; F124-V128 PolarHBondContact O-N 3.41Å; F124-L166 HydrophobicContact CD2-CD1 3.51Å; F124-L166 HydrophobicContact CE2-CD1 3.84Å; F124-A170 HydrophobicContact CD1-CB 3.98Å; F124-A170 HydrophobicContact CD2-CB 4.21Å; F124-A170 HydrophobicContact CE1-CB 3.76Å; F124-A170 HydrophobicContact CE2-CB 4.01Å; F124-A170 HydrophobicContact CG-CB 4.2Å; F124-A170 HydrophobicContact CZ-CB 3.77Å; F124-D173 HydrophobicContact CD1-CB 4.06Å; F124-D173 HydrophobicContact CE1-CB 4.42Å
125	L	91	Very high	82.9	Confident	0 Å²	0	28.5 Å²	28.5	0%	0	14%	0.136	C	C	.	.	H	α-helix	trans	-54.9	-50.4	171.7	176.4	63.2	0	0	0	110.3	L121 R127 V128 M129 H146 Y169 P389 Y392	L121-L125 WeakPolarHBondContact O-CB 3.34Å; L121-L125 PolarHBondContact O-N 2.87Å; L125-R127 VanDerWaalsContact C-N 3.32Å; L125-R127 PolarHBondContact O-N 3.34Å; L125-V128 PolarHBondContact O-N 3.4Å; L125-M129 HydrophobicContact CD1-CE 4.4Å; L125-M129 HydrophobicContact CD1-CG 4.04Å; L125-M129 HydrophobicContact CG-CG 4.4Å; L125-M129 WeakPolarHBondContact O-CB 3.4Å; L125-M129 VanDerWaalsContact O-CG 3.28Å; L125-M129 WeakPolarHBondContact O-CG 3.34Å; L125-M129 PolarHBondContact O-N 2.91Å; L125-H146 HydrophobicContact CD2-CB 3.46Å; L125-H146 VanDerWaalsContact CD2-CB 3.46Å; L125-Y169 HydrophobicContact CB-CD2 4.02Å; L125-Y169 HydrophobicContact CB-CE2 4.17Å; L125-Y169 HydrophobicContact CD1-CD2 4.37Å; L125-Y169 HydrophobicContact CD1-CE2 3.92Å; L125-P389 HydrophobicContact CD1-CB 3.53Å; L125-Y392 HydrophobicContact CD1-CD2 4.12Å; L125-Y392 HydrophobicContact CD2-CD2 4.09Å; L125-Y392 HydrophobicContact CD2-CE2 4.43Å; L125-Y392 HydrophobicContact CD2-CG 4.47Å
126	Y	90.9	Very high	84.4	Confident	3 Å²	3	28.8 Å²	28.8	1%	0.012	14%	0.139	C	C	.	.	H	α-helix	trans	-55	-46.9	177	-176.3	-97.1	0	0	0	112.2	E12 G122 I123 F124 M129 L130 D136 C139 V143	E12-Y126 HydrophobicContact CB-CE1 4.02Å; G122-Y126 WeakPolarHBondContact O-CB 3.41Å; G122-Y126 PolarHBondContact O-N 3.2Å; I123-Y126 PolarHBondContact O-N 3.32Å; F124-Y126 VanDerWaalsContact C-N 3.32Å; F124-Y126 PolarHBondContact O-N 3.41Å; Y126-M129 PolarHBondContact O-N 2.92Å; Y126-L130 HydrophobicContact CE1-CD2 4.02Å; Y126-L130 VanDerWaalsContact O-CB 3.3Å; Y126-L130 WeakPolarHBondContact O-CB 3.4Å; Y126-L130 PolarHBondContact O-N 3.23Å; Y126-D136 PolarHBondContact OH-OD1 3.32Å; Y126-C139 HydrophobicContact CD2-CB 3.83Å; Y126-C139 HydrophobicContact CE2-CB 3.52Å; Y126-V143 HydrophobicContact CD2-CG2 3.97Å; Y126-V143 HydrophobicContact CG-CG2 4.41Å
127	R	90.6	Very high	85.8	Confident	95 Å²	95	29.7 Å²	29.7	36%	0.358	14%	0.141	S	C	.	.	H	α-helix	trans	-64.2	-42.3	-179.6	-71	171.2	-176	177.4	7.6	112.7	I123 F124 L125 L130 F131	I123-R127 WeakPolarHBondContact O-CG 3.2Å; I123-R127 PolarHBondContact O-N 3.06Å; I123-R127 VanDerWaalsContact O-N 3.09Å; F124-R127 PolarHBondContact O-N 2.69Å; L125-R127 VanDerWaalsContact C-N 3.32Å; L125-R127 PolarHBondContact O-N 3.34Å; R127-L130 PolarHBondContact O-N 3.44Å; R127-F131 PolarHBondContact O-N 2.82Å
128	V	89.2	Confident	86.8	Confident	6 Å²	6	29.6 Å²	29.6	4%	0.036	14%	0.14	C	C	.	.	H	α-helix	trans	-65.4	-45.5	177.1	175.4	0	0	0	0	109.7	F124 L125 L130 F131 L132 M172 D173 P389	F124-V128 WeakPolarHBondContact O-CG2 3.37Å; F124-V128 PolarHBondContact O-N 3.41Å; L125-V128 PolarHBondContact O-N 3.4Å; V128-L130 PolarHBondContact O-N 3.19Å; V128-F131 WeakPolarHBondContact O-CB 3.28Å; V128-F131 PolarHBondContact O-N 3.17Å; V128-L132 HydrophobicContact CG1-CD1 4.1Å; V128-L132 HydrophobicContact CG1-CG 4.45Å; V128-L132 WeakPolarHBondContact O-CG 3.49Å; V128-L132 PolarHBondContact O-N 3.38Å; V128-M172 HydrophobicContact CG2-CB 4.18Å; V128-D173 HydrophobicContact CG2-CB 4.25Å; V128-P389 HydrophobicContact CG1-CG 4.21Å
129	M	90.7	Very high	87.6	Confident	0 Å²	0	29.5 Å²	29.5	0%	0	14%	0.139	C	C	.	.	H	α-helix	trans	-61.7	-43.1	176.6	-66.1	-56.1	91.5	0	0	112.3	L125 Y126 F131 L132 D133 C139 C142 P389 W393	L125-M129 HydrophobicContact CD1-CE 4.4Å; L125-M129 HydrophobicContact CD1-CG 4.04Å; L125-M129 HydrophobicContact CG-CG 4.4Å; L125-M129 WeakPolarHBondContact O-CB 3.4Å; L125-M129 VanDerWaalsContact O-CG 3.28Å; L125-M129 WeakPolarHBondContact O-CG 3.34Å; L125-M129 PolarHBondContact O-N 2.91Å; Y126-M129 PolarHBondContact O-N 2.92Å; M129-F131 PolarHBondContact O-N 3.42Å; M129-L132 HydrophobicContact CE-CD1 3.66Å; M129-L132 PolarHBondContact O-N 2.89Å; M129-L132 VanDerWaalsContact O-N 3.15Å; M129-D133 PolarHBondContact O-N 2.94Å; M129-C139 HydrophobicContact CB-CB 4Å; M129-C142 HydrophobicContact CG-CB 3.86Å; M129-C142 HydrophobicContact SD-CB 4.47Å; M129-P389 HydrophobicContact CE-CB 3.34Å; M129-P389 HydrophobicContact CE-CG 3.52Å; M129-P389 HydrophobicContact SD-CB 4.29Å; M129-W393 HydrophobicContact SD-CB 3.98Å; M129-W393 HydrophobicContact SD-CG 4.41Å
130	L	88.7	Confident	88.2	Confident	30 Å²	30	28.4 Å²	28.4	16%	0.157	14%	0.135	C	C	.	.	H	α-helix	trans	-63.6	-31.4	178.1	-171.3	66.9	0	0	0	112	Y126 R127 V128 G134 C139	Y126-L130 HydrophobicContact CE1-CD2 4.02Å; Y126-L130 VanDerWaalsContact O-CB 3.3Å; Y126-L130 WeakPolarHBondContact O-CB 3.4Å; Y126-L130 PolarHBondContact O-N 3.23Å; R127-L130 PolarHBondContact O-N 3.44Å; V128-L130 PolarHBondContact O-N 3.19Å; L130-G134 VanDerWaalsContact O-CA 3.23Å; L130-G134 WeakPolarHBondContact O-CA 3.3Å; L130-G134 PolarHBondContact O-N 3.15Å; L130-C139 WeakPolarHBondContact CA-SG 3.4Å; L130-C139 PolarHBondContact N-SG 3.31Å
131	F	87.1	Confident	88.6	Confident	43 Å²	43	25.6 Å²	25.6	19%	0.189	12%	0.121	C	C	.	.	H	α-helix	trans	-72.5	-41.1	174.1	177.7	-96.8	0	0	0	112.7	R127 V128 M129 F176 R177 R353 I356	R127-F131 PolarHBondContact O-N 2.82Å; V128-F131 WeakPolarHBondContact O-CB 3.28Å; V128-F131 PolarHBondContact O-N 3.17Å; M129-F131 PolarHBondContact O-N 3.42Å; F131-F176 HydrophobicContact CD1-CB 4.14Å; F131-F176 HydrophobicContact CE1-CB 3.64Å; F131-F176 HydrophobicContact CZ-CB 4.12Å; F131-F176 WeakPolarHBondContact CZ-O 3.31Å; F131-R177 HydrophobicContact CD2-CB 3.88Å; F131-R177 HydrophobicContact CD2-CG 3.94Å; F131-R177 HydrophobicContact CE2-CB 4.3Å; F131-R177 HydrophobicContact CG-CB 4.25Å; F131-R353 PolarHBondContact O-NE 3.46Å; F131-R353 VanDerWaalsContact O-NE 3.11Å; F131-I356 HydrophobicContact CE1-CD1 3.62Å; F131-I356 HydrophobicContact CZ-CD1 4.31Å
132	L	86.3	Confident	89	Confident	2 Å²	2	25.6 Å²	25.6	1%	0.01	12%	0.121	C	C	.	.	H	α-helix	trans	-74.7	-46.7	-177.6	-65.6	179	0	0	0	112.9	V128 M129 L348 R353 I356 L360	V128-L132 HydrophobicContact CG1-CD1 4.1Å; V128-L132 HydrophobicContact CG1-CG 4.45Å; V128-L132 WeakPolarHBondContact O-CG 3.49Å; V128-L132 PolarHBondContact O-N 3.38Å; M129-L132 HydrophobicContact CE-CD1 3.66Å; M129-L132 PolarHBondContact O-N 2.89Å; M129-L132 VanDerWaalsContact O-N 3.15Å; L132-L348 WeakPolarHBondContact O-CD1 3.34Å; L132-R353 WeakPolarHBondContact O-CD 3.25Å; L132-I356 HydrophobicContact CD2-CB 3.95Å; L132-I356 HydrophobicContact CD2-CG2 3.49Å; L132-I356 VanDerWaalsContact CD2-CG2 3.49Å; L132-L360 HydrophobicContact CD1-CD1 3.59Å
133	D	86	Confident	89.4	Confident	11 Å²	11	25.6 Å²	25.6	6%	0.059	12%	0.121	C	C	.	.	T	Hydrogen-bonded Turn	trans	-102.8	-48.7	-171	-170	-78.3	0	0	0	111.7	M129 R135 F138 W393	M129-D133 PolarHBondContact O-N 2.94Å; D133-R135 VanDerWaalsContact C-N 3.34Å; D133-R135 VanDerWaalsContact OD1-CB 3.29Å; D133-R135 WeakPolarHBondContact OD1-CB 3.5Å; D133-R135 WeakPolarHBondContact OD1-CG 3.48Å; D133-R135 IonicContact OD1-CZ 3.48Å; D133-R135 PolarHBondContact OD1-N 3.26Å; D133-R135 IonicContact OD1-NE 2.72Å; D133-R135 PolarHBondContact OD1-NE 3.15Å; D133-R135 IonicContact OD1-NH2 3.41Å; D133-R135 PolarHBondContact OD1-NH2 2.9Å; D133-R135 IonicContact OD2-CZ 3.6Å; D133-R135 IonicContact OD2-NE 3.61Å; D133-R135 IonicContact OD2-NH2 2.75Å; D133-R135 PolarHBondContact OD2-NH2 3.35Å; D133-F138 HydrophobicContact CB-CD1 3.99Å; D133-F138 HydrophobicContact CB-CE1 4.23Å; D133-W393 PolarHBondContact OD2-NE1 2.76Å
134	G	83.7	Confident	89.7	Confident	36 Å²	36	24.5 Å²	24.5	37%	0.371	12%	0.116	S	C	.	.			trans	88.5	-13.7	177.7	0	0	0	0	0	115.3	L130	L130-G134 VanDerWaalsContact O-CA 3.23Å; L130-G134 WeakPolarHBondContact O-CA 3.3Å; L130-G134 PolarHBondContact O-N 3.15Å
135	R	86.6	Confident	90	Very high	81 Å²	81	23.2 Å²	23.2	31%	0.306	11%	0.11	S	C	.	.			trans	-82.8	115.6	174.3	-62.5	173	-69.7	170.1	-0	110.3	D133 K137 F138 C139 Y400	D133-R135 VanDerWaalsContact C-N 3.34Å; D133-R135 VanDerWaalsContact OD1-CB 3.29Å; D133-R135 WeakPolarHBondContact OD1-CB 3.5Å; D133-R135 WeakPolarHBondContact OD1-CG 3.48Å; D133-R135 IonicContact OD1-CZ 3.48Å; D133-R135 PolarHBondContact OD1-N 3.26Å; D133-R135 IonicContact OD1-NE 2.72Å; D133-R135 PolarHBondContact OD1-NE 3.15Å; D133-R135 IonicContact OD1-NH2 3.41Å; D133-R135 PolarHBondContact OD1-NH2 2.9Å; D133-R135 IonicContact OD2-CZ 3.6Å; D133-R135 IonicContact OD2-NE 3.61Å; D133-R135 IonicContact OD2-NH2 2.75Å; D133-R135 PolarHBondContact OD2-NH2 3.35Å; R135-K137 PolarHBondContact O-N 3.17Å; R135-F138 HydrophobicContact CB-CB 3.77Å; R135-F138 WeakPolarHBondContact O-CB 3.4Å; R135-F138 PolarHBondContact O-N 3.14Å; R135-C139 PolarHBondContact O-N 3.25Å; R135-C139 PolarHBondContact O-SG 3.01Å; R135-Y400 VanDerWaalsContact NH1-CD1 3.27Å
136	D	87.1	Confident	90.2	Very high	57 Å²	57	23.4 Å²	23.4	31%	0.305	11%	0.111	S	C	.	.	H	α-helix	trans	-55.1	-51.4	-179.6	178.2	98.5	0	0	0	112.6	Y126 F138 C139 R140	Y126-D136 PolarHBondContact OH-OD1 3.32Å; D136-F138 VanDerWaalsContact C-N 3.28Å; D136-F138 PolarHBondContact O-N 3.13Å; D136-C139 PolarHBondContact O-N 2.94Å; D136-C139 VanDerWaalsContact O-N 3.07Å; D136-R140 PolarHBondContact O-N 2.94Å
137	K	88.1	Confident	90.3	Very high	83 Å²	83	23.4 Å²	23.4	36%	0.361	11%	0.112	S	C	.	.	H	α-helix	trans	-56.1	-41.7	178.7	-62	-173.4	-176.9	-167.2	0	112.7	R135 R140 L141 Y400 N407	R135-K137 PolarHBondContact O-N 3.17Å; K137-R140 PolarHBondContact O-N 3.07Å; K137-L141 PolarHBondContact O-N 3.14Å; K137-Y400 HydrophobicContact CB-CE2 4.27Å; K137-N407 WeakPolarHBondContact CE-OD1 3.49Å; K137-N407 PolarHBondContact NZ-OD1 3.27Å
138	F	90	Very high	90.5	Very high	0 Å²	0	19.5 Å²	19.5	0%	0	10%	0.098	C	C	.	.	H	α-helix	trans	-65.5	-45.2	177.6	-179.7	-84.3	0	0	0	111.3	D133 R135 D136 R140 L141 C142 W393 A396 Q397 Y400	D133-F138 HydrophobicContact CB-CD1 3.99Å; D133-F138 HydrophobicContact CB-CE1 4.23Å; R135-F138 HydrophobicContact CB-CB 3.77Å; R135-F138 WeakPolarHBondContact O-CB 3.4Å; R135-F138 PolarHBondContact O-N 3.14Å; D136-F138 VanDerWaalsContact C-N 3.28Å; D136-F138 PolarHBondContact O-N 3.13Å; F138-R140 VanDerWaalsContact C-N 3.25Å; F138-R140 PolarHBondContact O-N 3.35Å; F138-L141 WeakPolarHBondContact O-CB 3.47Å; F138-L141 PolarHBondContact O-N 2.62Å; F138-L141 VanDerWaalsContact O-N 3.13Å; F138-C142 VanDerWaalsContact CE1-SG 3.55Å; F138-C142 PolarHBondContact O-N 2.83Å; F138-W393 AromaticContact CE1-CD1 3.28Å; F138-W393 HydrophobicContact CE1-CG 4.08Å; F138-W393 AromaticContact CE1-NE1 3.39Å; F138-W393 AromaticContact CZ-CD1 3.56Å; F138-W393 HydrophobicContact CZ-CD2 4.3Å; F138-W393 AromaticContact CZ-CE2 3.97Å; F138-W393 HydrophobicContact CZ-CG 4Å; F138-W393 AromaticContact CZ-NE1 3.45Å; F138-W393 WeakPolarHBondContact CZ-O 3.21Å; F138-A396 HydrophobicContact CD2-CB 4.38Å; F138-A396 HydrophobicContact CE1-CB 4.18Å; F138-A396 HydrophobicContact CE2-CB 3.77Å; F138-A396 HydrophobicContact CZ-CB 3.65Å; F138-Q397 HydrophobicContact CE2-CB 4.18Å; F138-Q397 HydrophobicContact CZ-CB 4.37Å; F138-Y400 HydrophobicContact CB-CD2 4.46Å; F138-Y400 HydrophobicContact CD2-CD1 4.32Å; F138-Y400 HydrophobicContact CD2-CD2 4.25Å; F138-Y400 AromaticContact CD2-CG 3.91Å; F138-Y400 HydrophobicContact CD2-CG 3.91Å
139	C	91	Very high	90.8	Very high	0 Å²	0	19.2 Å²	19.2	0%	0	10%	0.096	C	C	.	.	H	α-helix	trans	-63.4	-36.1	179.1	-60.5	0	0	0	0	111.5	Y126 M129 L130 R135 D136 C142 V143	Y126-C139 HydrophobicContact CD2-CB 3.83Å; Y126-C139 HydrophobicContact CE2-CB 3.52Å; M129-C139 HydrophobicContact CB-CB 4Å; L130-C139 WeakPolarHBondContact CA-SG 3.4Å; L130-C139 PolarHBondContact N-SG 3.31Å; R135-C139 PolarHBondContact O-N 3.25Å; R135-C139 PolarHBondContact O-SG 3.01Å; D136-C139 PolarHBondContact O-N 2.94Å; D136-C139 VanDerWaalsContact O-N 3.07Å; C139-C142 WeakPolarHBondContact O-CB 3.37Å; C139-C142 PolarHBondContact O-N 3.15Å; C139-V143 PolarHBondContact O-N 2.96Å
140	R	91.4	Very high	91	Very high	41 Å²	41	19.2 Å²	19.2	16%	0.155	10%	0.096	C	C	.	.	H	α-helix	trans	-67.9	-36.7	174.8	-165.9	164.2	176.1	-140.3	-7.3	112.6	L19 D136 K137 F138 C142 V143 V144 L408 P409 N410	L19-R140 HydrophobicContact CD1-CG 4.45Å; D136-R140 PolarHBondContact O-N 2.94Å; K137-R140 PolarHBondContact O-N 3.07Å; F138-R140 VanDerWaalsContact C-N 3.25Å; F138-R140 PolarHBondContact O-N 3.35Å; R140-C142 VanDerWaalsContact C-N 3.35Å; R140-V143 PolarHBondContact O-N 3.43Å; R140-V144 PolarHBondContact O-N 2.89Å; R140-L408 PolarHBondContact NH1-O 3.08Å; R140-L408 PolarHBondContact NH2-O 2.9Å; R140-P409 PolarHBondContact NH2-O 2.8Å; R140-N410 PolarHBondContact NH2-OD1 2.82Å
141	L	93	Very high	91.3	Very high	0 Å²	0	17.9 Å²	17.9	0%	0	9%	0.089	C	C	.	.	H	α-helix	trans	-61.1	-42.1	170.8	177	60.9	0	0	0	111.5	K137 F138 V143 V144 L145 A396 I399 Y400 L406 L408 M419	K137-L141 PolarHBondContact O-N 3.14Å; F138-L141 WeakPolarHBondContact O-CB 3.47Å; F138-L141 PolarHBondContact O-N 2.62Å; F138-L141 VanDerWaalsContact O-N 3.13Å; L141-V143 VanDerWaalsContact C-N 3.27Å; L141-V143 PolarHBondContact O-N 3.38Å; L141-V144 PolarHBondContact O-N 3.19Å; L141-L145 HydrophobicContact CD1-CD1 4.36Å; L141-L145 HydrophobicContact CD1-CG 4.27Å; L141-L145 HydrophobicContact CG-CD1 4.19Å; L141-L145 WeakPolarHBondContact O-CG 3.36Å; L141-L145 PolarHBondContact O-N 3.43Å; L141-A396 HydrophobicContact CD2-CB 3.94Å; L141-A396 HydrophobicContact CG-CB 3.97Å; L141-I399 HydrophobicContact CD1-CG2 4.44Å; L141-I399 HydrophobicContact CD2-CB 4.16Å; L141-I399 HydrophobicContact CD2-CG2 4.01Å; L141-Y400 HydrophobicContact CD2-CD2 4.48Å; L141-L406 HydrophobicContact CD1-CD2 4.09Å; L141-L406 HydrophobicContact CD2-CD2 4.34Å; L141-L408 HydrophobicContact CB-CD1 4.02Å; L141-L408 HydrophobicContact CD1-CD1 4.09Å; L141-M419 HydrophobicContact CD1-CG 4.38Å; L141-M419 HydrophobicContact CD1-SD 3.49Å; L141-M419 WeakPolarHBondContact CD1-SD 3.3Å
142	C	94.6	Very high	91.5	Very high	0 Å²	0	16 Å²	16	0%	0	8%	0.082	C	C	.	.	H	α-helix	trans	-57.8	-39.3	173.6	-63.6	0	0	0	0	112.5	M129 F138 C139 R140 L145 H146 A396	M129-C142 HydrophobicContact CG-CB 3.86Å; M129-C142 HydrophobicContact SD-CB 4.47Å; F138-C142 VanDerWaalsContact CE1-SG 3.55Å; F138-C142 PolarHBondContact O-N 2.83Å; C139-C142 WeakPolarHBondContact O-CB 3.37Å; C139-C142 PolarHBondContact O-N 3.15Å; R140-C142 VanDerWaalsContact C-N 3.35Å; C142-L145 PolarHBondContact O-N 3.24Å; C142-H146 PolarHBondContact O-N 3.31Å; C142-A396 VanDerWaalsContact SG-CB 3.53Å
143	V	93.9	Very high	91.8	Very high	0 Å²	0	16 Å²	16	0%	0	8%	0.082	C	C	.	.	H	α-helix	trans	-68.6	-41.6	177	179.3	0	0	0	0	111.5	A16 L20 Y126 C139 R140 L141 L145 H146 C147	A16-V143 HydrophobicContact CB-CG1 4.06Å; L20-V143 HydrophobicContact CD1-CG1 4.48Å; L20-V143 HydrophobicContact CD2-CG1 3.91Å; L20-V143 HydrophobicContact CG-CG1 4.14Å; Y126-V143 HydrophobicContact CD2-CG2 3.97Å; Y126-V143 HydrophobicContact CG-CG2 4.41Å; C139-V143 PolarHBondContact O-N 2.96Å; R140-V143 PolarHBondContact O-N 3.43Å; L141-V143 VanDerWaalsContact C-N 3.27Å; L141-V143 PolarHBondContact O-N 3.38Å; V143-L145 VanDerWaalsContact C-N 3.29Å; V143-L145 PolarHBondContact O-N 2.84Å; V143-H146 WeakPolarHBondContact O-CB 3.48Å; V143-H146 PolarHBondContact O-N 3.3Å; V143-H146 VanDerWaalsContact O-N 3.11Å; V143-C147 PolarHBondContact O-N 2.91Å; V143-C147 PolarHBondContact O-SG 2.82Å; V143-C147 VanDerWaalsContact O-SG 3.35Å
144	V	94.4	Very high	92.2	Very high	0 Å²	0	15.6 Å²	15.6	0%	0	8%	0.079	C	C	.	.	H	α-helix	trans	-59.7	-41.9	173.9	169.4	0	0	0	0	111.1	L19 R140 L141 H146 C147 L148 L408 L412 C415 M419	L19-V144 HydrophobicContact CD1-CG2 3.77Å; R140-V144 PolarHBondContact O-N 2.89Å; L141-V144 PolarHBondContact O-N 3.19Å; V144-H146 VanDerWaalsContact C-N 3.29Å; V144-H146 PolarHBondContact O-N 3.04Å; V144-C147 WeakPolarHBondContact O-CB 3.29Å; V144-C147 PolarHBondContact O-N 3.16Å; V144-L148 HydrophobicContact CG1-CD1 4.11Å; V144-L148 WeakPolarHBondContact O-CG 3.18Å; V144-L148 PolarHBondContact O-N 3.1Å; V144-L148 VanDerWaalsContact O-N 3.07Å; V144-L408 HydrophobicContact CG2-CD1 4.05Å; V144-L412 HydrophobicContact CG1-CD1 4.08Å; V144-C415 HydrophobicContact CG1-CB 4.01Å; V144-C415 HydrophobicContact CG2-CB 4.45Å; V144-M419 HydrophobicContact CG1-CE 3.72Å; V144-M419 HydrophobicContact CG1-SD 4.06Å
145	L	95.5	Very high	92.6	Very high	0 Å²	0	14 Å²	14	0%	0	6%	0.062	C	C	.	.	H	α-helix	trans	-67.2	-29.6	176	-69.2	171.9	0	0	0	112.8	L141 C142 V143 L148 S149 Y392 A395 A396 I399 F434	L141-L145 HydrophobicContact CD1-CD1 4.36Å; L141-L145 HydrophobicContact CD1-CG 4.27Å; L141-L145 HydrophobicContact CG-CD1 4.19Å; L141-L145 WeakPolarHBondContact O-CG 3.36Å; L141-L145 PolarHBondContact O-N 3.43Å; C142-L145 PolarHBondContact O-N 3.24Å; V143-L145 VanDerWaalsContact C-N 3.29Å; V143-L145 PolarHBondContact O-N 2.84Å; L145-L148 CarbonylContact O-C 3.33Å; L145-L148 PolarHBondContact O-N 3.46Å; L145-S149 WeakPolarHBondContact O-CA 3.26Å; L145-S149 PolarHBondContact O-N 3.25Å; L145-Y392 HydrophobicContact CB-CD1 4.2Å; L145-A395 HydrophobicContact CD1-CB 3.82Å; L145-A396 HydrophobicContact CD1-CB 3.86Å; L145-I399 HydrophobicContact CD1-CD1 4.3Å; L145-I399 HydrophobicContact CD2-CD1 3.92Å; L145-F434 HydrophobicContact CB-CD1 4.38Å; L145-F434 HydrophobicContact CB-CE1 3.87Å; L145-F434 HydrophobicContact CD2-CD1 3.96Å; L145-F434 HydrophobicContact CD2-CE1 3.98Å; L145-F434 HydrophobicContact CG-CE1 4.46Å; L145-F434 WeakPolarHBondContact O-CE1 3.16Å
146	H	95.1	Very high	92.8	Very high	3 Å²	3	10.7 Å²	10.7	1%	0.014	5%	0.05	C	C	.	.	H	α-helix	trans	-68.6	-42.3	170.8	169.7	55.1	0	0	0	112.3	D118 L121 L125 C142 V143 V144 L148 S149 Y392	D118-H146 IonicContact OD1-CE1 3.62Å; D118-H146 IonicContact OD1-NE2 2.66Å; D118-H146 PolarHBondContact OD1-NE2 3.13Å; L121-H146 VanDerWaalsContact CD2-CE1 3.47Å; L121-H146 WeakPolarHBondContact CD2-CE1 3.48Å; L125-H146 HydrophobicContact CD2-CB 3.46Å; L125-H146 VanDerWaalsContact CD2-CB 3.46Å; C142-H146 PolarHBondContact O-N 3.31Å; V143-H146 WeakPolarHBondContact O-CB 3.48Å; V143-H146 PolarHBondContact O-N 3.3Å; V143-H146 VanDerWaalsContact O-N 3.11Å; V144-H146 VanDerWaalsContact C-N 3.29Å; V144-H146 PolarHBondContact O-N 3.04Å; H146-L148 PolarHBondContact O-N 3.35Å; H146-S149 WeakPolarHBondContact O-CB 3.28Å; H146-S149 PolarHBondContact O-N 3.23Å; H146-S149 VanDerWaalsContact O-N 3.15Å; H146-Y392 VanDerWaalsContact CA-CE1 3.44Å; H146-Y392 HydrophobicContact CB-CD1 4.25Å; H146-Y392 HydrophobicContact CB-CE1 3.88Å; H146-Y392 HydrophobicContact CB-CE2 4.37Å; H146-Y392 AromaticContact ND1-CZ 3.72Å; H146-Y392 PolarHBondContact ND1-OH 3.36Å
147	C	93.9	Very high	92.9	Very high	4 Å²	4	8 Å²	8	3%	0.027	4%	0.035	C	C	.	.	H	α-helix	trans	-58.2	-34.7	171.7	-64.6	0	0	0	0	112.4	S23 V143 V144 T152 L412	S23-C147 WeakPolarHBondContact OG-CA 3.37Å; S23-C147 PolarHBondContact OG-O 3.05Å; S23-C147 VanDerWaalsContact OG-O 3.11Å; V143-C147 PolarHBondContact O-N 2.91Å; V143-C147 PolarHBondContact O-SG 2.82Å; V143-C147 VanDerWaalsContact O-SG 3.35Å; V144-C147 WeakPolarHBondContact O-CB 3.29Å; V144-C147 PolarHBondContact O-N 3.16Å; C147-T152 PolarHBondContact O-OG1 3.29Å; C147-L412 HydrophobicContact CB-CD1 3.7Å; C147-L412 HydrophobicContact CB-CD2 3.86Å; C147-L412 HydrophobicContact CB-CG 4.46Å
148	L	94.9	Very high	93	Very high	13 Å²	13	4.4 Å²	4.4	7%	0.068	2%	0.02	C	C	.	.	T	Hydrogen-bonded Turn	trans	-99.4	19.7	-179.3	-55.7	177	0	0	0	112.8	V144 L145 H146 L412 I416 M419 L431 F434 L435	V144-L148 HydrophobicContact CG1-CD1 4.11Å; V144-L148 WeakPolarHBondContact O-CG 3.18Å; V144-L148 PolarHBondContact O-N 3.1Å; V144-L148 VanDerWaalsContact O-N 3.07Å; L145-L148 CarbonylContact O-C 3.33Å; L145-L148 PolarHBondContact O-N 3.46Å; H146-L148 PolarHBondContact O-N 3.35Å; L148-L412 HydrophobicContact CD1-CD1 4.49Å; L148-L412 HydrophobicContact CD2-CD1 4.07Å; L148-L412 HydrophobicContact CD2-CD2 4.18Å; L148-L412 HydrophobicContact CD2-CG 4.17Å; L148-L412 HydrophobicContact CG-CD1 4.12Å; L148-I416 HydrophobicContact CD1-CD1 4.5Å; L148-I416 HydrophobicContact CD1-CG1 4Å; L148-I416 HydrophobicContact CD2-CD1 4.41Å; L148-M419 HydrophobicContact CD1-CE 4Å; L148-L431 HydrophobicContact CD1-CD1 4.32Å; L148-F434 CarbonylContact O-C 3.38Å; L148-F434 WeakPolarHBondContact O-CB 3.26Å; L148-F434 WeakPolarHBondContact O-CD1 3.01Å; L148-L435 HydrophobicContact CD1-CD2 4.09Å; L148-L435 HydrophobicContact CD2-CD2 3.96Å; L148-L435 HydrophobicContact CG-CD2 4.44Å
149	S	94.3	Very high	93.2	Very high	0 Å²	0	4.7 Å²	4.7	0%	0	2%	0.021	C	C	.	.			trans	-61.2	144.3	-169.2	-176.7	0	0	0	0	112.8	L145 H146 A151 T152 Y392	L145-S149 WeakPolarHBondContact O-CA 3.26Å; L145-S149 PolarHBondContact O-N 3.25Å; H146-S149 WeakPolarHBondContact O-CB 3.28Å; H146-S149 PolarHBondContact O-N 3.23Å; H146-S149 VanDerWaalsContact O-N 3.15Å; S149-A151 PolarHBondContact O-N 2.95Å; S149-A151 PolarHBondContact OG-N 3.47Å; S149-T152 PolarHBondContact N-OG1 3.44Å; S149-T152 VanDerWaalsContact N-OG1 3.13Å; S149-T152 WeakPolarHBondContact O-CB 3.38Å; S149-T152 PolarHBondContact O-N 3.41Å; S149-T152 PolarHBondContact O-OG1 3.1Å; S149-Y392 WeakPolarHBondContact CB-OH 3.3Å; S149-Y392 PolarHBondContact OG-OH 2.96Å
150	P	95.4	Very high	93.3	Very high	0 Å²	0	4.8 Å²	4.8	0%	0	2%	0.022	C	C	.	.	T	Hydrogen-bonded Turn	trans	-56.6	-22.2	167.1	-26.7	36.3	0	0	0	113.7	T381 F385 W433 F434 Y437	P150-T381 HydrophobicContact CB-CG2 3.64Å; P150-F385 HydrophobicContact CB-CD2 4.37Å; P150-F385 HydrophobicContact CB-CE2 3.96Å; P150-F385 HydrophobicContact CG-CD2 4.39Å; P150-F385 HydrophobicContact CG-CE2 3.62Å; P150-F385 HydrophobicContact CG-CZ 3.71Å; P150-W433 HydrophobicContact CB-CZ2 3.91Å; P150-W433 HydrophobicContact CG-CD2 4.33Å; P150-W433 HydrophobicContact CG-CE3 4.49Å; P150-W433 HydrophobicContact CG-CH2 3.72Å; P150-W433 HydrophobicContact CG-CZ2 3.46Å; P150-W433 VanDerWaalsContact CG-CZ2 3.46Å; P150-W433 HydrophobicContact CG-CZ3 4.22Å; P150-F434 HydrophobicContact CG-CD1 4.4Å; P150-F434 HydrophobicContact CG-CD2 4.16Å; P150-F434 HydrophobicContact CG-CE2 4.36Å; P150-F434 HydrophobicContact CG-CG 4.2Å; P150-Y437 HydrophobicContact CB-CD1 3.85Å; P150-Y437 HydrophobicContact CB-CG 4.08Å
151	A	94.3	Very high	93.4	Very high	1 Å²	1	2.9 Å²	2.9	1%	0.008	2%	0.015	C	C	.	.	T	Hydrogen-bonded Turn	trans	-95.1	9.8	176.8	0	0	0	0	0	113.6	S149 V153 F154 F155 F385	S149-A151 PolarHBondContact O-N 2.95Å; S149-A151 PolarHBondContact OG-N 3.47Å; A151-V153 VanDerWaalsContact C-N 3.25Å; A151-V153 PolarHBondContact O-N 3.28Å; A151-V153 VanDerWaalsContact O-N 3.13Å; A151-F154 HydrophobicContact CB-CD2 4.24Å; A151-F154 PolarHBondContact O-N 3.02Å; A151-F155 HydrophobicContact CB-CD2 4.28Å; A151-F155 HydrophobicContact CB-CE2 3.75Å; A151-F155 HydrophobicContact CB-CZ 4.35Å; A151-F155 WeakPolarHBondContact O-CD2 3.48Å; A151-F155 PolarHBondContact O-N 3.37Å; A151-F385 HydrophobicContact CB-CB 3.84Å; A151-F385 HydrophobicContact CB-CG 4.5Å
152	T	93	Very high	93.4	Very high	5 Å²	5	2.9 Å²	2.9	3%	0.031	2%	0.015	C	C	.	.	H	α-helix	trans	-49.3	-43	-175.2	-76.3	0	0	0	0	112.7	A27 C147 S149 F154 F155 H156 I442	A27-T152 HydrophobicContact CB-CG2 4.42Å; C147-T152 PolarHBondContact O-OG1 3.29Å; S149-T152 PolarHBondContact N-OG1 3.44Å; S149-T152 VanDerWaalsContact N-OG1 3.13Å; S149-T152 WeakPolarHBondContact O-CB 3.38Å; S149-T152 PolarHBondContact O-N 3.41Å; S149-T152 PolarHBondContact O-OG1 3.1Å; T152-F154 VanDerWaalsContact C-N 3.27Å; T152-F154 PolarHBondContact O-N 2.94Å; T152-F155 PolarHBondContact O-N 3.29Å; T152-F155 VanDerWaalsContact O-N 3.08Å; T152-H156 WeakPolarHBondContact CG2-ND1 3.42Å; T152-H156 PolarHBondContact O-N 2.98Å; T152-H156 PolarHBondContact O-ND1 3.44Å; T152-I442 HydrophobicContact CG2-CD1 4.15Å
153	V	92.8	Very high	93.3	Very high	2 Å²	2	3 Å²	3	1%	0.012	2%	0.016	C	C	.	.	H	α-helix	trans	-60.6	-34.7	-179.5	69	0	0	0	0	113.2	A151 H156 S157 I442 H445	A151-V153 VanDerWaalsContact C-N 3.25Å; A151-V153 PolarHBondContact O-N 3.28Å; A151-V153 VanDerWaalsContact O-N 3.13Å; V153-H156 PolarHBondContact O-N 3.07Å; V153-S157 WeakPolarHBondContact O-CB 3.41Å; V153-S157 PolarHBondContact O-N 3.24Å; V153-S157 PolarHBondContact O-OG 3.35Å; V153-I442 HydrophobicContact CB-CG1 4.04Å; V153-I442 HydrophobicContact CG2-CG1 4.23Å; V153-H445 HydrophobicContact CG1-CB 4.41Å; V153-H445 HydrophobicContact CG2-CB 3.65Å
154	F	93.2	Very high	93.4	Very high	2 Å²	2	3.1 Å²	3.1	1%	0.009	2%	0.016	C	C	.	.	H	α-helix	trans	-77.9	-20.9	178	-52.8	-72.5	0	0	0	113.3	A151 T152 Y159 E161 R382 W451 T452	A151-F154 HydrophobicContact CB-CD2 4.24Å; A151-F154 PolarHBondContact O-N 3.02Å; T152-F154 VanDerWaalsContact C-N 3.27Å; T152-F154 PolarHBondContact O-N 2.94Å; F154-Y159 AromaticContact CD1-CD1 3.63Å; F154-Y159 HydrophobicContact CD1-CD1 3.63Å; F154-Y159 AromaticContact CD1-CE1 3.52Å; F154-Y159 HydrophobicContact CD1-CE1 3.52Å; F154-Y159 HydrophobicContact CD1-CE2 4.46Å; F154-Y159 HydrophobicContact CD1-CG 4.13Å; F154-Y159 AromaticContact CD1-CZ 3.93Å; F154-Y159 HydrophobicContact CE1-CD1 4.41Å; F154-Y159 AromaticContact CE1-CE1 3.85Å; F154-Y159 HydrophobicContact CE1-CE1 3.85Å; F154-Y159 WeakPolarHBondContact O-CB 3.19Å; F154-E161 HydrophobicContact CB-CB 4.16Å; F154-E161 HydrophobicContact CB-CG 4.03Å; F154-R382 HydrophobicContact CD2-CB 3.53Å; F154-R382 HydrophobicContact CE2-CB 3.81Å; F154-R382 HydrophobicContact CG-CB 3.99Å; F154-R382 HydrophobicContact CZ-CB 4.46Å; F154-W451 AromaticContact CZ-CD1 3.94Å; F154-T452 WeakPolarHBondContact CE2-OG1 3.24Å; F154-T452 WeakPolarHBondContact CZ-O 3.33Å; F154-T452 VanDerWaalsContact CZ-OG1 3.27Å; F154-T452 WeakPolarHBondContact CZ-OG1 3.37Å
155	F	92.2	Very high	93.4	Very high	2 Å²	2	3.1 Å²	3.1	1%	0.009	2%	0.016	C	C	.	.	H	α-helix	trans	-78.4	-26.7	173.1	-66.7	-55.2	0	0	0	112.6	L121 A151 T152 E161 A165 Y392	L121-F155 HydrophobicContact CD2-CD1 3.89Å; L121-F155 HydrophobicContact CD2-CE1 3.91Å; A151-F155 HydrophobicContact CB-CD2 4.28Å; A151-F155 HydrophobicContact CB-CE2 3.75Å; A151-F155 HydrophobicContact CB-CZ 4.35Å; A151-F155 WeakPolarHBondContact O-CD2 3.48Å; A151-F155 PolarHBondContact O-N 3.37Å; T152-F155 PolarHBondContact O-N 3.29Å; T152-F155 VanDerWaalsContact O-N 3.08Å; F155-E161 HydrophobicContact CD1-CB 4.46Å; F155-E161 HydrophobicContact CE1-CB 4.42Å; F155-A165 HydrophobicContact CE1-CB 4.12Å; F155-Y392 WeakPolarHBondContact CE2-OH 3.36Å
156	H	90.4	Very high	93.4	Very high	11 Å²	11	3.8 Å²	3.8	5%	0.051	2%	0.02	C	C	.	.	H	α-helix	trans	-103.7	-27.3	-175.5	-62.6	83.3	0	0	0	114.4	A27 Y68 D118 T152 V153	A27-H156 HydrophobicContact CB-CB 4.29Å; Y68-H156 HydrophobicContact CE1-CB 4.31Å; D118-H156 IonicContact OD2-NE2 2.7Å; T152-H156 WeakPolarHBondContact CG2-ND1 3.42Å; T152-H156 PolarHBondContact O-N 2.98Å; T152-H156 PolarHBondContact O-ND1 3.44Å; V153-H156 PolarHBondContact O-N 3.07Å
157	S	90.2	Very high	93.4	Very high	0 Å²	0	6.5 Å²	6.5	0%	0	3%	0.03	C	C	.	.	S	Bend	trans	-77.5	178.4	175.8	60.4	0	0	0	0	112.1	V153 Y159	V153-S157 WeakPolarHBondContact O-CB 3.41Å; V153-S157 PolarHBondContact O-N 3.24Å; V153-S157 PolarHBondContact O-OG 3.35Å; S157-Y159 PolarHBondContact O-N 2.9Å; S157-Y159 WeakPolarHBondContact OG-CD2 3.36Å
158	I	90.6	Very high	93.5	Very high	9 Å²	9	6.3 Å²	6.3	5%	0.046	3%	0.029	C	C	.	.	S	Bend	trans	-78.5	63.4	-178	-53.6	177.5	0	0	0	109.7	T69 S73 F76 L77 L96 I100 F114	T69-I158 HydrophobicContact CG2-CD1 4.33Å; S73-I158 PolarHBondContact OG-N 2.59Å; S73-I158 PolarHBondContact OG-O 3.22Å; F76-I158 HydrophobicContact CB-CG2 4.08Å; F76-I158 WeakPolarHBondContact CD2-O 3.31Å; L77-I158 HydrophobicContact CD1-CD1 3.84Å; L77-I158 HydrophobicContact CD2-CD1 3.81Å; L77-I158 HydrophobicContact CD2-CG2 4.44Å; L77-I158 HydrophobicContact CG-CD1 3.92Å; L77-I158 HydrophobicContact CG-CG2 4.29Å; L96-I158 HydrophobicContact CD2-CG2 4.35Å; I100-I158 HydrophobicContact CD1-CG2 3.83Å; F114-I158 HydrophobicContact CE1-CB 4.06Å; F114-I158 HydrophobicContact CE1-CG1 4.14Å; F114-I158 HydrophobicContact CE1-CG2 3.94Å; F114-I158 HydrophobicContact CE2-CG1 4.1Å; F114-I158 HydrophobicContact CZ-CB 4.04Å; F114-I158 HydrophobicContact CZ-CG1 3.81Å; F114-I158 HydrophobicContact CZ-CG2 3.67Å
159	Y	92.6	Very high	93.5	Very high	5 Å²	5	5.8 Å²	5.8	2%	0.02	3%	0.026	C	C	.	.			trans	-123.8	152	-175.9	-90.2	-109.5	0	0	0	110.2	W71 D72 S73 L96 F154 S157 E161 H445	W71-Y159 WeakPolarHBondContact CB-OH 3.42Å; D72-Y159 HydrophobicContact CB-CD1 4.28Å; D72-Y159 HydrophobicContact CB-CE1 3.51Å; D72-Y159 HydrophobicContact CB-CE2 4.16Å; D72-Y159 VanDerWaalsContact CB-CZ 3.49Å; D72-Y159 PolarHBondContact N-OH 3.37Å; D72-Y159 VanDerWaalsContact N-OH 3.16Å; D72-Y159 WeakPolarHBondContact OD2-CE1 3.44Å; S73-Y159 WeakPolarHBondContact OG-CD2 3.12Å; S73-Y159 WeakPolarHBondContact OG-CE2 3.44Å; L96-Y159 VanDerWaalsContact CD2-C 3.44Å; F154-Y159 AromaticContact CD1-CD1 3.63Å; F154-Y159 HydrophobicContact CD1-CD1 3.63Å; F154-Y159 AromaticContact CD1-CE1 3.52Å; F154-Y159 HydrophobicContact CD1-CE1 3.52Å; F154-Y159 HydrophobicContact CD1-CE2 4.46Å; F154-Y159 HydrophobicContact CD1-CG 4.13Å; F154-Y159 AromaticContact CD1-CZ 3.93Å; F154-Y159 HydrophobicContact CE1-CD1 4.41Å; F154-Y159 AromaticContact CE1-CE1 3.85Å; F154-Y159 HydrophobicContact CE1-CE1 3.85Å; F154-Y159 WeakPolarHBondContact O-CB 3.19Å; S157-Y159 PolarHBondContact O-N 2.9Å; S157-Y159 WeakPolarHBondContact OG-CD2 3.36Å; Y159-E161 VanDerWaalsContact C-N 3.29Å; Y159-E161 WeakPolarHBondContact CB-OE2 3.49Å; Y159-E161 WeakPolarHBondContact CD1-OE2 3.3Å; Y159-E161 PolarHBondContact O-N 2.86Å; Y159-H445 AromaticContact CE2-CE1 3.84Å; Y159-H445 AromaticContact CE2-NE2 3.31Å; Y159-H445 VanDerWaalsContact CE2-NE2 3.31Å; Y159-H445 WeakPolarHBondContact CE2-NE2 3.27Å; Y159-H445 AromaticContact CZ-NE2 3.52Å; Y159-H445 PolarHBondContact OH-NE2 2.95Å; Y159-H445 VanDerWaalsContact OH-NE2 3.1Å
160	S	93.8	Very high	93.6	Very high	2 Å²	2	5.8 Å²	5.8	1%	0.014	3%	0.026	C	C	.	.	S	Bend	trans	-82.9	-6.5	-176.6	63.6	0	0	0	0	113.6	S162 L163 F164 A194 R195	S160-S162 PolarHBondContact O-N 3.18Å; S160-L163 PolarHBondContact O-N 3.45Å; S160-F164 WeakPolarHBondContact O-CB 3.27Å; S160-F164 PolarHBondContact O-N 3.29Å; S160-A194 WeakPolarHBondContact CB-O 3.42Å; S160-A194 PolarHBondContact OG-O 3.07Å; S160-R195 WeakPolarHBondContact OG-CG 3.4Å; S160-R195 PolarHBondContact OG-NH1 3.32Å
161	E	93.6	Very high	93.6	Very high	1 Å²	1	5.8 Å²	5.8	1%	0.005	3%	0.026	C	C	.	.	H	α-helix	trans	-56.9	-43.2	-177.8	-83.4	74.4	179	0	0	112.9	F154 F155 Y159 F164 A165 R195 R382	F154-E161 HydrophobicContact CB-CB 4.16Å; F154-E161 HydrophobicContact CB-CG 4.03Å; F155-E161 HydrophobicContact CD1-CB 4.46Å; F155-E161 HydrophobicContact CE1-CB 4.42Å; Y159-E161 VanDerWaalsContact C-N 3.29Å; Y159-E161 WeakPolarHBondContact CB-OE2 3.49Å; Y159-E161 WeakPolarHBondContact CD1-OE2 3.3Å; Y159-E161 PolarHBondContact O-N 2.86Å; E161-F164 PolarHBondContact O-N 3.48Å; E161-A165 VanDerWaalsContact O-CB 3.24Å; E161-A165 WeakPolarHBondContact O-CB 3.34Å; E161-A165 PolarHBondContact O-N 3.27Å; E161-R195 VanDerWaalsContact CD-CZ 3.42Å; E161-R195 IonicContact OE1-CZ 3.49Å; E161-R195 IonicContact OE1-NH1 3.83Å; E161-R195 PolarHBondContact OE1-NH1 3.09Å; E161-R195 IonicContact OE1-NH2 3.63Å; E161-R195 PolarHBondContact OE1-NH2 3.12Å; E161-R195 IonicContact OE2-CZ 3.94Å; E161-R195 IonicContact OE2-NH1 3.54Å; E161-R195 PolarHBondContact OE2-NH1 3.2Å; E161-R382 IonicContact OE1-NH1 3.32Å
162	S	92.6	Very high	93.7	Very high	0 Å²	0	5.8 Å²	5.8	0%	0	3%	0.026	C	C	.	.	H	α-helix	trans	-66.5	-46.7	179.3	54.8	0	0	0	0	112.3	S117 S160 A165 L166	S117-S162 VanDerWaalsContact OG-CB 3.32Å; S117-S162 WeakPolarHBondContact OG-CB 3.3Å; S117-S162 PolarHBondContact OG-OG 3.01Å; S117-S162 VanDerWaalsContact OG-OG 3.11Å; S160-S162 PolarHBondContact O-N 3.18Å; S162-A165 PolarHBondContact O-N 3.03Å; S162-L166 VanDerWaalsContact O-CB 3.26Å; S162-L166 WeakPolarHBondContact O-CB 3.33Å; S162-L166 PolarHBondContact O-N 2.91Å
163	L	93.2	Very high	93.7	Very high	4 Å²	4	5.8 Å²	5.8	2%	0.021	3%	0.025	C	C	.	.	H	α-helix	trans	-62.6	-45.8	174.4	-69.7	174.7	0	0	0	111.2	L96 M99 F113 S160 A165 L166 W167 A194	L96-L163 HydrophobicContact CB-CD1 3.99Å; L96-L163 HydrophobicContact CD1-CD1 3.77Å; L96-L163 HydrophobicContact CG-CD1 4.47Å; M99-L163 HydrophobicContact SD-CD1 3.87Å; M99-L163 HydrophobicContact SD-CD2 4.13Å; F113-L163 HydrophobicContact CE1-CD2 4.22Å; S160-L163 PolarHBondContact O-N 3.45Å; L163-A165 PolarHBondContact O-N 3.37Å; L163-L166 PolarHBondContact O-N 3.35Å; L163-W167 PolarHBondContact O-N 3.5Å; L163-A194 HydrophobicContact CB-CB 4.36Å
164	F	95.5	Very high	93.9	Very high	1 Å²	1	8.1 Å²	8.1	0%	0.004	4%	0.035	C	C	.	.	H	α-helix	trans	-58.1	-48.3	177.5	164.9	-102.9	0	0	0	111.8	S160 E161 S168 S191 A194 R195 N197 C387	S160-F164 WeakPolarHBondContact O-CB 3.27Å; S160-F164 PolarHBondContact O-N 3.29Å; E161-F164 PolarHBondContact O-N 3.48Å; F164-S168 WeakPolarHBondContact CE2-OG 3.02Å; F164-S168 VanDerWaalsContact O-CB 3.28Å; F164-S168 WeakPolarHBondContact O-CB 3.02Å; F164-S168 PolarHBondContact O-N 3.11Å; F164-S168 PolarHBondContact O-OG 3.06Å; F164-S191 WeakPolarHBondContact CD2-O 3.45Å; F164-A194 HydrophobicContact CB-CB 4Å; F164-R195 HydrophobicContact CB-CB 4.46Å; F164-R195 HydrophobicContact CB-CG 3.96Å; F164-R195 HydrophobicContact CD2-CB 4.01Å; F164-R195 HydrophobicContact CD2-CG 4.4Å; F164-R195 HydrophobicContact CG-CB 4.24Å; F164-R195 HydrophobicContact CG-CG 4.15Å; F164-N197 HydrophobicContact CE2-CB 4.46Å; F164-N197 HydrophobicContact CZ-CB 4.33Å; F164-C387 HydrophobicContact CE1-CB 4.03Å; F164-C387 WeakPolarHBondContact CE1-SG 3.37Å; F164-C387 HydrophobicContact CZ-CB 4.2Å; F164-C387 WeakPolarHBondContact CZ-SG 3.4Å
165	A	94.7	Very high	94	Very high	0 Å²	0	8 Å²	8	0%	0	4%	0.035	C	C	.	.	H	α-helix	trans	-65.2	-42.5	178.9	0	0	0	0	0	111.5	L121 F155 E161 S162 L163 W167 S168 Y169 S386	L121-A165 HydrophobicContact CD1-CB 3.54Å; L121-A165 HydrophobicContact CD2-CB 3.85Å; L121-A165 HydrophobicContact CG-CB 4.36Å; F155-A165 HydrophobicContact CE1-CB 4.12Å; E161-A165 VanDerWaalsContact O-CB 3.24Å; E161-A165 WeakPolarHBondContact O-CB 3.34Å; E161-A165 PolarHBondContact O-N 3.27Å; S162-A165 PolarHBondContact O-N 3.03Å; L163-A165 PolarHBondContact O-N 3.37Å; A165-W167 PolarHBondContact O-N 2.9Å; A165-S168 PolarHBondContact O-N 2.9Å; A165-Y169 WeakPolarHBondContact O-CB 3.42Å; A165-Y169 PolarHBondContact O-N 3.32Å; A165-S386 WeakPolarHBondContact CA-O 3.24Å; A165-S386 VanDerWaalsContact CB-O 3.28Å; A165-S386 WeakPolarHBondContact CB-O 3.33Å
166	L	94.4	Very high	94	Very high	14 Å²	14	8.3 Å²	8.3	7%	0.073	4%	0.037	C	C	.	.	H	α-helix	trans	-55.9	-53.6	178.8	167.8	60.7	0	0	0	110.8	Q120 L121 F124 S162 L163 S168 Y169 A170	Q120-L166 HydrophobicContact CB-CD1 3.57Å; Q120-L166 HydrophobicContact CB-CD2 4.29Å; L121-L166 HydrophobicContact CB-CB 4.37Å; F124-L166 HydrophobicContact CD2-CD1 3.51Å; F124-L166 HydrophobicContact CE2-CD1 3.84Å; S162-L166 VanDerWaalsContact O-CB 3.26Å; S162-L166 WeakPolarHBondContact O-CB 3.33Å; S162-L166 PolarHBondContact O-N 2.91Å; L163-L166 PolarHBondContact O-N 3.35Å; L166-S168 VanDerWaalsContact C-N 3.35Å; L166-Y169 PolarHBondContact O-N 2.84Å; L166-A170 VanDerWaalsContact O-CB 3.25Å; L166-A170 WeakPolarHBondContact O-CB 3.22Å; L166-A170 PolarHBondContact O-N 3.41Å
167	W	95.4	Very high	94	Very high	61 Å²	61	11.8 Å²	11.8	23%	0.231	5%	0.049	C	C	.	.	H	α-helix	trans	-71.7	-31.7	-176.8	-63	122.1	0	0	0	112.4	F95 L163 A165 G171 L187 L190	F95-W167 AromaticContact CE1-CD1 3.6Å; F95-W167 AromaticContact CE1-NE1 3.31Å; F95-W167 VanDerWaalsContact CE1-NE1 3.31Å; F95-W167 AromaticContact CZ-NE1 3.66Å; L163-W167 PolarHBondContact O-N 3.5Å; A165-W167 PolarHBondContact O-N 2.9Å; W167-G171 PolarHBondContact O-N 3.23Å; W167-L187 WeakPolarHBondContact CB-O 3.3Å; W167-L187 HydrophobicContact CE3-CD2 3.62Å; W167-L187 HydrophobicContact CZ3-CD2 3.68Å; W167-L190 HydrophobicContact CB-CB 4.05Å; W167-L190 HydrophobicContact CD2-CB 3.98Å; W167-L190 HydrophobicContact CD2-CD1 3.85Å; W167-L190 HydrophobicContact CE3-CD1 3.75Å; W167-L190 HydrophobicContact CG-CB 3.74Å; W167-L190 HydrophobicContact CG-CD1 4.5Å; W167-L190 HydrophobicContact CH2-CD1 4.1Å; W167-L190 HydrophobicContact CZ2-CD1 4.19Å; W167-L190 HydrophobicContact CZ3-CD1 3.88Å
168	S	96.5	Very high	94	Very high	0 Å²	0	15.4 Å²	15.4	0%	0	7%	0.065	C	C	.	.	H	α-helix	trans	-63.9	-49.9	172	-61.8	0	0	0	0	111.5	F164 A165 L166 G171 M172 F188 S191 N201	F164-S168 WeakPolarHBondContact CE2-OG 3.02Å; F164-S168 VanDerWaalsContact O-CB 3.28Å; F164-S168 WeakPolarHBondContact O-CB 3.02Å; F164-S168 PolarHBondContact O-N 3.11Å; F164-S168 PolarHBondContact O-OG 3.06Å; A165-S168 PolarHBondContact O-N 2.9Å; L166-S168 VanDerWaalsContact C-N 3.35Å; S168-G171 PolarHBondContact O-N 3.33Å; S168-M172 WeakPolarHBondContact O-CG 3.27Å; S168-M172 PolarHBondContact O-N 3.41Å; S168-F188 WeakPolarHBondContact O-CE1 3.3Å; S168-S191 WeakPolarHBondContact OG-CB 3.33Å; S168-N201 PolarHBondContact OG-ND2 3.4Å; S168-N201 VanDerWaalsContact OG-ND2 3.07Å
169	Y	95.5	Very high	94.2	Very high	1 Å²	1	20.6 Å²	20.6	0%	0.004	8%	0.084	C	C	.	.	H	α-helix	trans	-70.8	-34.4	-179.4	-65	-7	0	0	0	112.3	L121 L125 A165 L166 G171 M172 D173 F385 S388 P389	L121-Y169 HydrophobicContact CD1-CD2 3.36Å; L121-Y169 HydrophobicContact CD1-CE2 3.57Å; L121-Y169 HydrophobicContact CD1-CG 4.28Å; L125-Y169 HydrophobicContact CB-CD2 4.02Å; L125-Y169 HydrophobicContact CB-CE2 4.17Å; L125-Y169 HydrophobicContact CD1-CD2 4.37Å; L125-Y169 HydrophobicContact CD1-CE2 3.92Å; A165-Y169 WeakPolarHBondContact O-CB 3.42Å; A165-Y169 PolarHBondContact O-N 3.32Å; L166-Y169 PolarHBondContact O-N 2.84Å; Y169-G171 VanDerWaalsContact C-N 3.35Å; Y169-M172 HydrophobicContact CD1-CE 4.07Å; Y169-M172 HydrophobicContact CD1-SD 4.07Å; Y169-M172 HydrophobicContact CE1-CE 4.3Å; Y169-M172 PolarHBondContact O-N 2.84Å; Y169-D173 WeakPolarHBondContact O-CB 3.34Å; Y169-D173 PolarHBondContact O-N 3.42Å; Y169-F385 PolarHBondContact OH-O 2.94Å; Y169-S388 VanDerWaalsContact OH-C 3.25Å; Y169-S388 PolarHBondContact OH-O 3.05Å; Y169-P389 HydrophobicContact CE1-CB 4.3Å; Y169-P389 HydrophobicContact CE1-CG 4.34Å
170	A	95.2	Very high	94.3	Very high	1 Å²	1	24.4 Å²	24.4	1%	0.008	10%	0.102	C	C	.	.	H	α-helix	trans	-61.1	-44.6	169.8	0	0	0	0	0	111	F124 L166 M172 D173 F174 L187	F124-A170 HydrophobicContact CD1-CB 3.98Å; F124-A170 HydrophobicContact CD2-CB 4.21Å; F124-A170 HydrophobicContact CE1-CB 3.76Å; F124-A170 HydrophobicContact CE2-CB 4.01Å; F124-A170 HydrophobicContact CG-CB 4.2Å; F124-A170 HydrophobicContact CZ-CB 3.77Å; L166-A170 VanDerWaalsContact O-CB 3.25Å; L166-A170 WeakPolarHBondContact O-CB 3.22Å; L166-A170 PolarHBondContact O-N 3.41Å; A170-M172 PolarHBondContact O-N 3.07Å; A170-D173 PolarHBondContact O-N 2.89Å; A170-F174 WeakPolarHBondContact O-CD2 3.43Å; A170-F174 PolarHBondContact O-N 3.43Å; A170-L187 HydrophobicContact CB-CD1 4.02Å; A170-L187 HydrophobicContact CB-CD2 4.4Å
171	G	96.9	Very high	94.5	Very high	0 Å²	0	24.9 Å²	24.9	0%	0	11%	0.105	C	C	.	.	H	α-helix	trans	-58.5	-45.6	174.3	0	0	0	0	0	112.7	W167 S168 Y169 D173 F174 L175 A184 F188	W167-G171 PolarHBondContact O-N 3.23Å; S168-G171 PolarHBondContact O-N 3.33Å; Y169-G171 VanDerWaalsContact C-N 3.35Å; G171-D173 PolarHBondContact O-N 3.39Å; G171-F174 PolarHBondContact O-N 3.45Å; G171-L175 VanDerWaalsContact O-CB 3.28Å; G171-L175 WeakPolarHBondContact O-CB 3.48Å; G171-L175 PolarHBondContact O-N 3.2Å; G171-A184 WeakPolarHBondContact O-CB 3.32Å; G171-F188 VanDerWaalsContact C-CZ 3.46Å
172	M	95.6	Very high	94.6	Very high	1 Å²	1	28.7 Å²	28.7	1%	0.005	13%	0.128	C	C	.	.	H	α-helix	trans	-60.7	-43	175	-66.3	180	-160.2	0	0	112.4	V128 S168 Y169 A170 L175 F176 F188 F204 L360 P389	V128-M172 HydrophobicContact CG2-CB 4.18Å; S168-M172 WeakPolarHBondContact O-CG 3.27Å; S168-M172 PolarHBondContact O-N 3.41Å; Y169-M172 HydrophobicContact CD1-CE 4.07Å; Y169-M172 HydrophobicContact CD1-SD 4.07Å; Y169-M172 HydrophobicContact CE1-CE 4.3Å; Y169-M172 PolarHBondContact O-N 2.84Å; A170-M172 PolarHBondContact O-N 3.07Å; M172-L175 PolarHBondContact O-N 3.41Å; M172-F176 HydrophobicContact CB-CD2 4.11Å; M172-F176 HydrophobicContact CB-CE2 4.16Å; M172-F176 HydrophobicContact CG-CE2 4.27Å; M172-F176 VanDerWaalsContact O-CD2 3.26Å; M172-F176 WeakPolarHBondContact O-CD2 3.31Å; M172-F176 PolarHBondContact O-N 2.92Å; M172-F188 HydrophobicContact CG-CE1 4.28Å; M172-F188 HydrophobicContact CG-CZ 4.32Å; M172-F204 HydrophobicContact CE-CD2 4.36Å; M172-F204 HydrophobicContact CE-CE2 3.53Å; M172-F204 HydrophobicContact CE-CZ 3.64Å; M172-L360 HydrophobicContact CE-CD2 4.45Å; M172-L360 HydrophobicContact SD-CD2 4.21Å; M172-P389 HydrophobicContact SD-CG 4.48Å
173	D	93.8	Very high	94.9	Very high	4 Å²	4	31.8 Å²	31.8	2%	0.021	14%	0.144	C	C	.	.	I	π-helix	trans	-61	-47.2	177.9	-175.5	55.6	0	0	0	111.5	F124 V128 Y169 A170 G171 L175 R177 K178	F124-D173 HydrophobicContact CD1-CB 4.06Å; F124-D173 HydrophobicContact CE1-CB 4.42Å; V128-D173 HydrophobicContact CG2-CB 4.25Å; Y169-D173 WeakPolarHBondContact O-CB 3.34Å; Y169-D173 PolarHBondContact O-N 3.42Å; A170-D173 PolarHBondContact O-N 2.89Å; G171-D173 PolarHBondContact O-N 3.39Å; D173-L175 VanDerWaalsContact C-N 3.35Å; D173-L175 PolarHBondContact O-N 3.5Å; D173-R177 VanDerWaalsContact CG-NH2 3.35Å; D173-R177 WeakPolarHBondContact O-CA 3.43Å; D173-R177 VanDerWaalsContact O-CB 3.3Å; D173-R177 WeakPolarHBondContact O-CB 3.16Å; D173-R177 PolarHBondContact O-N 3.37Å; D173-R177 IonicContact OD1-CZ 2.92Å; D173-R177 VanDerWaalsContact OD1-CZ 3.32Å; D173-R177 IonicContact OD1-NE 2.77Å; D173-R177 PolarHBondContact OD1-NE 2.88Å; D173-R177 IonicContact OD1-NH2 3.01Å; D173-R177 PolarHBondContact OD1-NH2 3.17Å; D173-R177 VanDerWaalsContact OD1-NH2 3.16Å; D173-R177 IonicContact OD2-CZ 2.84Å; D173-R177 IonicContact OD2-NE 2.8Å; D173-R177 IonicContact OD2-NH2 3.63Å; D173-R177 PolarHBondContact OD2-NH2 2.99Å; D173-K178 PolarHBondContact O-N 2.95Å; D173-K178 VanDerWaalsContact O-N 3.11Å
174	F	95.8	Very high	95.1	Very high	51 Å²	51	31.6 Å²	31.6	22%	0.224	14%	0.143	C	C	.	.	I	π-helix	trans	-67.6	-35.8	178	-87.9	-96.6	0	0	0	112.5	A170 G171 K178 R179 Q180 I183 A184 L187	A170-F174 WeakPolarHBondContact O-CD2 3.43Å; A170-F174 PolarHBondContact O-N 3.43Å; G171-F174 PolarHBondContact O-N 3.45Å; F174-K178 HydrophobicContact CD1-CB 4.25Å; F174-K178 HydrophobicContact CD1-CG 4.27Å; F174-K178 HydrophobicContact CG-CG 4.5Å; F174-K178 CarbonylContact O-C 3.52Å; F174-K178 WeakPolarHBondContact O-CB 3.09Å; F174-R179 PolarHBondContact O-N 3.4Å; F174-Q180 HydrophobicContact CD1-CB 4.18Å; F174-Q180 VanDerWaalsContact CE1-OE1 3.29Å; F174-Q180 PolarHBondContact O-N 3.43Å; F174-I183 HydrophobicContact CB-CG2 4.44Å; F174-I183 HydrophobicContact CD1-CB 3.83Å; F174-I183 HydrophobicContact CD1-CD1 4.2Å; F174-I183 HydrophobicContact CD1-CG2 3.41Å; F174-I183 VanDerWaalsContact CD1-CG2 3.41Å; F174-I183 HydrophobicContact CE1-CB 4.35Å; F174-I183 HydrophobicContact CE1-CD1 4.09Å; F174-I183 HydrophobicContact CE1-CG2 3.65Å; F174-I183 HydrophobicContact CG-CB 4.45Å; F174-I183 HydrophobicContact CG-CG2 3.88Å; F174-I183 HydrophobicContact CZ-CG2 4.29Å; F174-A184 HydrophobicContact CB-CB 4.21Å; F174-L187 HydrophobicContact CB-CD1 4.09Å; F174-L187 HydrophobicContact CD2-CD1 3.46Å; F174-L187 VanDerWaalsContact CD2-CD1 3.46Å; F174-L187 HydrophobicContact CE2-CD1 4.01Å; F174-L187 HydrophobicContact CG-CD1 3.84Å
175	L	95.6	Very high	95.3	Very high	0 Å²	0	31.6 Å²	31.6	0%	0	14%	0.143	C	C	.	.	I	π-helix	trans	-70.1	-55.8	179.4	-170.6	64.2	0	0	0	111.8	G171 M172 D173 R179 P181 A184 F188 F204 L205 Y208	G171-L175 VanDerWaalsContact O-CB 3.28Å; G171-L175 WeakPolarHBondContact O-CB 3.48Å; G171-L175 PolarHBondContact O-N 3.2Å; M172-L175 PolarHBondContact O-N 3.41Å; D173-L175 VanDerWaalsContact C-N 3.35Å; D173-L175 PolarHBondContact O-N 3.5Å; L175-R179 WeakPolarHBondContact O-CA 3.37Å; L175-R179 PolarHBondContact O-N 2.87Å; L175-P181 HydrophobicContact CD1-CB 3.78Å; L175-A184 HydrophobicContact CB-CB 3.71Å; L175-A184 HydrophobicContact CD1-CB 4.08Å; L175-A184 HydrophobicContact CG-CB 4.45Å; L175-F188 HydrophobicContact CD2-CE2 4.19Å; L175-F188 HydrophobicContact CD2-CZ 4.47Å; L175-F204 HydrophobicContact CD2-CB 3.69Å; L175-F204 WeakPolarHBondContact CD2-O 3.39Å; L175-L205 HydrophobicContact CD1-CD2 3.88Å; L175-L205 HydrophobicContact CD2-CD2 4.37Å; L175-Y208 HydrophobicContact CD1-CD1 4.17Å; L175-Y208 HydrophobicContact CD1-CD2 3.7Å; L175-Y208 HydrophobicContact CD1-CE2 4.3Å; L175-Y208 HydrophobicContact CD1-CG 3.62Å; L175-Y208 HydrophobicContact CG-CD2 3.86Å; L175-Y208 HydrophobicContact CG-CG 4.13Å; L175-Y208 WeakPolarHBondContact O-CE2 3.28Å
176	F	92.1	Very high	95.5	Very high	9 Å²	9	36 Å²	36	4%	0.039	17%	0.166	C	C	.	.	I	π-helix	trans	-86.1	-44.5	-169.5	-60.4	-52.7	0	0	0	113	F131 M172 R179 F204 F207 I356 L359	F131-F176 HydrophobicContact CD1-CB 4.14Å; F131-F176 HydrophobicContact CE1-CB 3.64Å; F131-F176 HydrophobicContact CZ-CB 4.12Å; F131-F176 WeakPolarHBondContact CZ-O 3.31Å; M172-F176 HydrophobicContact CB-CD2 4.11Å; M172-F176 HydrophobicContact CB-CE2 4.16Å; M172-F176 HydrophobicContact CG-CE2 4.27Å; M172-F176 VanDerWaalsContact O-CD2 3.26Å; M172-F176 WeakPolarHBondContact O-CD2 3.31Å; M172-F176 PolarHBondContact O-N 2.92Å; F176-R179 PolarHBondContact O-NE 3.26Å; F176-F204 HydrophobicContact CE2-CD1 4.31Å; F176-F204 HydrophobicContact CZ-CB 4.25Å; F176-F204 AromaticContact CZ-CD1 3.94Å; F176-F204 HydrophobicContact CZ-CD1 3.94Å; F176-F204 HydrophobicContact CZ-CG 4.4Å; F176-F207 HydrophobicContact CE1-CD1 4.08Å; F176-F207 HydrophobicContact CE1-CE1 4.26Å; F176-I356 HydrophobicContact CB-CD1 4.09Å; F176-I356 HydrophobicContact CD1-CD1 3.63Å; F176-I356 HydrophobicContact CD1-CG1 3.96Å; F176-I356 HydrophobicContact CD1-CG2 4.47Å; F176-I356 HydrophobicContact CD2-CG2 4.07Å; F176-I356 HydrophobicContact CE1-CD1 4.2Å; F176-I356 HydrophobicContact CE1-CG1 4Å; F176-I356 HydrophobicContact CE1-CG2 4.3Å; F176-I356 HydrophobicContact CE2-CG2 3.87Å; F176-I356 HydrophobicContact CG-CD1 3.86Å; F176-I356 HydrophobicContact CG-CG1 4.45Å; F176-I356 HydrophobicContact CG-CG2 4.38Å; F176-I356 HydrophobicContact CZ-CG2 4Å; F176-L359 HydrophobicContact CE1-CD2 4.28Å; F176-L359 HydrophobicContact CZ-CD2 3.82Å
177	R	89.7	Confident	95.6	Very high	84 Å²	84	36.4 Å²	36.4	32%	0.317	17%	0.168	S	C	.	.	I	π-helix	trans	-87.3	-44.6	-176.1	-172.1	-178	63	107.8	-3.8	112.1	F131 D173	F131-R177 HydrophobicContact CD2-CB 3.88Å; F131-R177 HydrophobicContact CD2-CG 3.94Å; F131-R177 HydrophobicContact CE2-CB 4.3Å; F131-R177 HydrophobicContact CG-CB 4.25Å; D173-R177 VanDerWaalsContact CG-NH2 3.35Å; D173-R177 WeakPolarHBondContact O-CA 3.43Å; D173-R177 VanDerWaalsContact O-CB 3.3Å; D173-R177 WeakPolarHBondContact O-CB 3.16Å; D173-R177 PolarHBondContact O-N 3.37Å; D173-R177 IonicContact OD1-CZ 2.92Å; D173-R177 VanDerWaalsContact OD1-CZ 3.32Å; D173-R177 IonicContact OD1-NE 2.77Å; D173-R177 PolarHBondContact OD1-NE 2.88Å; D173-R177 IonicContact OD1-NH2 3.01Å; D173-R177 PolarHBondContact OD1-NH2 3.17Å; D173-R177 VanDerWaalsContact OD1-NH2 3.16Å; D173-R177 IonicContact OD2-CZ 2.84Å; D173-R177 IonicContact OD2-NE 2.8Å; D173-R177 IonicContact OD2-NH2 3.63Å; D173-R177 PolarHBondContact OD2-NH2 2.99Å
178	K	91.9	Very high	95.8	Very high	76 Å²	76	33.5 Å²	33.5	33%	0.33	16%	0.157	S	C	.	.	S	Bend	trans	-86.1	-15.6	-179.9	-60	-62.1	-168.2	176.3	0	114.2	Y6 D173 F174 Q180	Y6-K178 PolarHBondContact OH-NZ 3.45Å; D173-K178 PolarHBondContact O-N 2.95Å; D173-K178 VanDerWaalsContact O-N 3.11Å; F174-K178 HydrophobicContact CD1-CB 4.25Å; F174-K178 HydrophobicContact CD1-CG 4.27Å; F174-K178 HydrophobicContact CG-CG 4.5Å; F174-K178 CarbonylContact O-C 3.52Å; F174-K178 WeakPolarHBondContact O-CB 3.09Å; K178-Q180 HydrophobicContact CB-CB 4.31Å; K178-Q180 HydrophobicContact CB-CG 4.2Å; K178-Q180 PolarHBondContact O-N 3.35Å
179	R	92.8	Very high	95.9	Very high	118 Å²	118	34.2 Å²	34.2	45%	0.445	16%	0.162	S	C	.	.			trans	56.1	36.7	-176.2	-56.9	-64	-171.9	116.5	0	112.1	F174 L175 F176 P181	F174-R179 PolarHBondContact O-N 3.4Å; L175-R179 WeakPolarHBondContact O-CA 3.37Å; L175-R179 PolarHBondContact O-N 2.87Å; F176-R179 PolarHBondContact O-NE 3.26Å; R179-P181 WeakPolarHBondContact O-CD 3.39Å
180	Q	96.3	Very high	96	Very high	84 Å²	84	36.9 Å²	36.9	39%	0.393	18%	0.176	S	C	.	.			trans	-113.7	73.7	-179	-74.3	177.9	-27.8	0	0	110.1	F174 K178 T182 I183 A184	F174-Q180 HydrophobicContact CD1-CB 4.18Å; F174-Q180 VanDerWaalsContact CE1-OE1 3.29Å; F174-Q180 PolarHBondContact O-N 3.43Å; K178-Q180 HydrophobicContact CB-CB 4.31Å; K178-Q180 HydrophobicContact CB-CG 4.2Å; K178-Q180 PolarHBondContact O-N 3.35Å; Q180-T182 VanDerWaalsContact C-N 3.26Å; Q180-T182 PolarHBondContact O-N 3.02Å; Q180-I183 HydrophobicContact CB-CB 4.3Å; Q180-I183 HydrophobicContact CB-CD1 4.24Å; Q180-I183 HydrophobicContact CB-CG1 4.46Å; Q180-I183 HydrophobicContact CG-CD1 4.48Å; Q180-I183 PolarHBondContact O-N 3.39Å; Q180-A184 PolarHBondContact O-N 3.34Å
181	P	96.7	Very high	96.1	Very high	13 Å²	13	36.8 Å²	36.8	8%	0.084	18%	0.176	C	C	.	.	H	α-helix	trans	-63.9	-27.3	-172.8	26.6	-38	0	0	0	114	L175 R179 A185 Y208 R241	L175-P181 HydrophobicContact CD1-CB 3.78Å; R179-P181 WeakPolarHBondContact O-CD 3.39Å; P181-A185 WeakPolarHBondContact O-CB 3.41Å; P181-A185 PolarHBondContact O-N 3.38Å; P181-Y208 HydrophobicContact CB-CD1 4.2Å; P181-Y208 HydrophobicContact CB-CE1 4.1Å; P181-Y208 HydrophobicContact CG-CE1 3.97Å; P181-R241 VanDerWaalsContact CG-NH1 3.33Å
182	T	97.5	Very high	96.2	Very high	81 Å²	81	36.8 Å²	36.8	50%	0.497	18%	0.176	S	C	.	.	H	α-helix	trans	-69.8	-43.4	176.2	-53.8	0	0	0	0	111.6	Q180 A184 A185 L186 R241	Q180-T182 VanDerWaalsContact C-N 3.26Å; Q180-T182 PolarHBondContact O-N 3.02Å; T182-A184 VanDerWaalsContact C-N 3.33Å; T182-A185 PolarHBondContact O-N 3.11Å; T182-L186 PolarHBondContact O-N 2.95Å; T182-R241 PolarHBondContact OG1-NE 3.18Å
183	I	98.2	Very high	96.3	Very high	64 Å²	64	37.6 Å²	37.6	33%	0.328	18%	0.183	S	C	.	.	H	α-helix	trans	-67.8	-39.8	175.7	-61	174.9	0	0	0	109.7	F174 Q180 A185 L186 L187	F174-I183 HydrophobicContact CB-CG2 4.44Å; F174-I183 HydrophobicContact CD1-CB 3.83Å; F174-I183 HydrophobicContact CD1-CD1 4.2Å; F174-I183 HydrophobicContact CD1-CG2 3.41Å; F174-I183 VanDerWaalsContact CD1-CG2 3.41Å; F174-I183 HydrophobicContact CE1-CB 4.35Å; F174-I183 HydrophobicContact CE1-CD1 4.09Å; F174-I183 HydrophobicContact CE1-CG2 3.65Å; F174-I183 HydrophobicContact CG-CB 4.45Å; F174-I183 HydrophobicContact CG-CG2 3.88Å; F174-I183 HydrophobicContact CZ-CG2 4.29Å; Q180-I183 HydrophobicContact CB-CB 4.3Å; Q180-I183 HydrophobicContact CB-CD1 4.24Å; Q180-I183 HydrophobicContact CB-CG1 4.46Å; Q180-I183 HydrophobicContact CG-CD1 4.48Å; Q180-I183 PolarHBondContact O-N 3.39Å; I183-A185 VanDerWaalsContact C-N 3.31Å; I183-A185 PolarHBondContact O-N 3.41Å; I183-L186 PolarHBondContact O-N 2.67Å; I183-L187 HydrophobicContact CG2-CD1 3.97Å; I183-L187 HydrophobicContact CG2-CG 4.35Å; I183-L187 WeakPolarHBondContact O-CG 3.23Å; I183-L187 PolarHBondContact O-N 3.31Å
184	A	98.1	Very high	96.4	Very high	0 Å²	0	37.4 Å²	37.4	0%	0	18%	0.182	C	C	.	.	H	α-helix	trans	-58.1	-42	174.2	0	0	0	0	0	112.6	G171 F174 L175 Q180 T182 L186 L187 F188	G171-A184 WeakPolarHBondContact O-CB 3.32Å; F174-A184 HydrophobicContact CB-CB 4.21Å; L175-A184 HydrophobicContact CB-CB 3.71Å; L175-A184 HydrophobicContact CD1-CB 4.08Å; L175-A184 HydrophobicContact CG-CB 4.45Å; Q180-A184 PolarHBondContact O-N 3.34Å; T182-A184 VanDerWaalsContact C-N 3.33Å; A184-L186 VanDerWaalsContact C-N 3.35Å; A184-L186 PolarHBondContact O-N 2.72Å; A184-L187 PolarHBondContact O-N 3.47Å; A184-F188 HydrophobicContact CB-CD2 4.5Å; A184-F188 HydrophobicContact CB-CE2 4.19Å; A184-F188 WeakPolarHBondContact O-CB 3.33Å; A184-F188 WeakPolarHBondContact O-CD2 3.23Å; A184-F188 VanDerWaalsContact O-CG 3.28Å; A184-F188 WeakPolarHBondContact O-CG 3.29Å; A184-F188 PolarHBondContact O-N 3.08Å
185	A	98.6	Very high	96.4	Very high	1 Å²	1	36.7 Å²	36.7	1%	0.008	18%	0.178	C	C	.	.	H	α-helix	trans	-62.2	-39.4	176.1	0	0	0	0	0	112.7	P181 T182 I183 F188 S189 L205 R241 V244 V245	P181-A185 WeakPolarHBondContact O-CB 3.41Å; P181-A185 PolarHBondContact O-N 3.38Å; T182-A185 PolarHBondContact O-N 3.11Å; I183-A185 VanDerWaalsContact C-N 3.31Å; I183-A185 PolarHBondContact O-N 3.41Å; A185-F188 PolarHBondContact O-N 3.19Å; A185-S189 PolarHBondContact O-N 2.92Å; A185-L205 HydrophobicContact CB-CD1 4.19Å; A185-R241 HydrophobicContact CB-CB 3.84Å; A185-R241 HydrophobicContact CB-CG 4.13Å; A185-V244 HydrophobicContact CB-CG1 4.44Å; A185-V245 HydrophobicContact CB-CG2 4.14Å; A185-V245 WeakPolarHBondContact O-CG2 3.47Å
186	L	98.5	Very high	96.3	Very high	93 Å²	93	37.4 Å²	37.4	49%	0.487	18%	0.183	S	C	.	.	H	α-helix	trans	-65.8	-38.2	173.8	-66.9	170.2	0	0	0	112.2	T182 I183 A184 S189 L190 V244	T182-L186 PolarHBondContact O-N 2.95Å; I183-L186 PolarHBondContact O-N 2.67Å; A184-L186 VanDerWaalsContact C-N 3.35Å; A184-L186 PolarHBondContact O-N 2.72Å; L186-S189 PolarHBondContact O-N 3.15Å; L186-S189 PolarHBondContact O-OG 3.44Å; L186-L190 PolarHBondContact O-N 3.11Å; L186-V244 HydrophobicContact CD2-CG1 3.82Å
187	L	98.1	Very high	96.4	Very high	22 Å²	22	38.3 Å²	38.3	12%	0.115	19%	0.188	C	C	.	.	H	α-helix	trans	-70.8	-39.6	176.5	-63.5	167.8	0	0	0	111.1	W167 A170 F174 I183 A184 S189 L190 S191	W167-L187 WeakPolarHBondContact CB-O 3.3Å; W167-L187 HydrophobicContact CE3-CD2 3.62Å; W167-L187 HydrophobicContact CZ3-CD2 3.68Å; A170-L187 HydrophobicContact CB-CD1 4.02Å; A170-L187 HydrophobicContact CB-CD2 4.4Å; F174-L187 HydrophobicContact CB-CD1 4.09Å; F174-L187 HydrophobicContact CD2-CD1 3.46Å; F174-L187 VanDerWaalsContact CD2-CD1 3.46Å; F174-L187 HydrophobicContact CE2-CD1 4.01Å; F174-L187 HydrophobicContact CG-CD1 3.84Å; I183-L187 HydrophobicContact CG2-CD1 3.97Å; I183-L187 HydrophobicContact CG2-CG 4.35Å; I183-L187 WeakPolarHBondContact O-CG 3.23Å; I183-L187 PolarHBondContact O-N 3.31Å; A184-L187 PolarHBondContact O-N 3.47Å; L187-S189 VanDerWaalsContact C-N 3.31Å; L187-S189 PolarHBondContact O-N 3.21Å; L187-L190 WeakPolarHBondContact O-CB 3.38Å; L187-L190 PolarHBondContact O-N 2.98Å; L187-S191 PolarHBondContact O-N 3.41Å; L187-S191 VanDerWaalsContact O-N 3.13Å
188	F	98.4	Very high	96.7	Very high	0 Å²	0	34.3 Å²	34.3	0%	0	17%	0.173	C	C	.	.	H	α-helix	trans	-65	-33.6	172.9	-67	-39.7	0	0	0	112.3	S168 G171 M172 L175 A184 A185 L190 S191 V192 N201 F204 L205 V245	S168-F188 WeakPolarHBondContact O-CE1 3.3Å; G171-F188 VanDerWaalsContact C-CZ 3.46Å; M172-F188 HydrophobicContact CG-CE1 4.28Å; M172-F188 HydrophobicContact CG-CZ 4.32Å; L175-F188 HydrophobicContact CD2-CE2 4.19Å; L175-F188 HydrophobicContact CD2-CZ 4.47Å; A184-F188 HydrophobicContact CB-CD2 4.5Å; A184-F188 HydrophobicContact CB-CE2 4.19Å; A184-F188 WeakPolarHBondContact O-CB 3.33Å; A184-F188 WeakPolarHBondContact O-CD2 3.23Å; A184-F188 VanDerWaalsContact O-CG 3.28Å; A184-F188 WeakPolarHBondContact O-CG 3.29Å; A184-F188 PolarHBondContact O-N 3.08Å; A185-F188 PolarHBondContact O-N 3.19Å; F188-L190 VanDerWaalsContact C-N 3.32Å; F188-L190 PolarHBondContact O-N 3.06Å; F188-S191 WeakPolarHBondContact O-CB 3.38Å; F188-S191 PolarHBondContact O-N 2.94Å; F188-S191 VanDerWaalsContact O-N 3.11Å; F188-S191 PolarHBondContact O-OG 3.41Å; F188-V192 PolarHBondContact O-N 3.06Å; F188-N201 HydrophobicContact CB-CB 4.17Å; F188-N201 HydrophobicContact CD1-CB 3.59Å; F188-N201 HydrophobicContact CD2-CB 4.3Å; F188-N201 HydrophobicContact CE1-CB 3.96Å; F188-N201 HydrophobicContact CG-CB 3.78Å; F188-N201 HydrophobicContact CZ-CB 4.48Å; F188-F204 HydrophobicContact CE1-CD2 4.28Å; F188-F204 HydrophobicContact CE2-CB 4.21Å; F188-F204 HydrophobicContact CZ-CB 4.11Å; F188-F204 AromaticContact CZ-CD2 3.99Å; F188-F204 HydrophobicContact CZ-CD2 3.99Å; F188-F204 HydrophobicContact CZ-CG 4.39Å; F188-L205 HydrophobicContact CD2-CD2 4.34Å; F188-L205 HydrophobicContact CD2-CG 4.3Å; F188-L205 HydrophobicContact CE2-CD2 4.23Å; F188-L205 HydrophobicContact CE2-CG 4.37Å; F188-V245 HydrophobicContact CB-CG1 4.14Å; F188-V245 HydrophobicContact CB-CG2 3.77Å
189	S	98.4	Very high	97	Very high	15 Å²	15	32.8 Å²	32.8	11%	0.105	17%	0.168	C	C	.	.	H	α-helix	trans	-64.4	-37.4	174	80.1	0	0	0	0	111.7	A185 L186 L187 S191 V192 A193 V244 P248	A185-S189 PolarHBondContact O-N 2.92Å; L186-S189 PolarHBondContact O-N 3.15Å; L186-S189 PolarHBondContact O-OG 3.44Å; L187-S189 VanDerWaalsContact C-N 3.31Å; L187-S189 PolarHBondContact O-N 3.21Å; S189-S191 VanDerWaalsContact C-N 3.3Å; S189-S191 PolarHBondContact O-N 3.13Å; S189-V192 WeakPolarHBondContact O-CB 3.34Å; S189-V192 PolarHBondContact O-N 3.42Å; S189-V192 VanDerWaalsContact O-N 3.12Å; S189-A193 PolarHBondContact O-N 2.91Å; S189-V244 VanDerWaalsContact CB-O 3.25Å; S189-V244 WeakPolarHBondContact CB-O 3.47Å; S189-P248 WeakPolarHBondContact O-CG 3.24Å
190	L	97.7	Very high	97.2	Very high	57 Å²	57	28.3 Å²	28.3	30%	0.298	15%	0.154	S	C	.	.	H	α-helix	trans	-62.9	-35.3	171.2	-65.5	176.1	0	0	0	112.5	F95 W167 L186 L187 F188 V192 A193 A194	F95-L190 WeakPolarHBondContact CD1-O 3.4Å; F95-L190 HydrophobicContact CE1-CB 4.03Å; F95-L190 HydrophobicContact CE1-CD2 4.18Å; F95-L190 HydrophobicContact CZ-CD2 4.07Å; W167-L190 HydrophobicContact CB-CB 4.05Å; W167-L190 HydrophobicContact CD2-CB 3.98Å; W167-L190 HydrophobicContact CD2-CD1 3.85Å; W167-L190 HydrophobicContact CE3-CD1 3.75Å; W167-L190 HydrophobicContact CG-CB 3.74Å; W167-L190 HydrophobicContact CG-CD1 4.5Å; W167-L190 HydrophobicContact CH2-CD1 4.1Å; W167-L190 HydrophobicContact CZ2-CD1 4.19Å; W167-L190 HydrophobicContact CZ3-CD1 3.88Å; L186-L190 PolarHBondContact O-N 3.11Å; L187-L190 WeakPolarHBondContact O-CB 3.38Å; L187-L190 PolarHBondContact O-N 2.98Å; F188-L190 VanDerWaalsContact C-N 3.32Å; F188-L190 PolarHBondContact O-N 3.06Å; L190-V192 VanDerWaalsContact C-N 3.34Å; L190-A193 PolarHBondContact O-N 3.07Å; L190-A194 PolarHBondContact O-N 3.25Å
191	S	97.4	Very high	97.2	Very high	0 Å²	0	24.3 Å²	24.3	0%	0	14%	0.135	C	C	.	.	H	α-helix	trans	-64	-39.4	172.3	80.1	0	0	0	0	111.9	F164 S168 L187 F188 S189 A194 R195 N201	F164-S191 WeakPolarHBondContact CD2-O 3.45Å; S168-S191 WeakPolarHBondContact OG-CB 3.33Å; L187-S191 PolarHBondContact O-N 3.41Å; L187-S191 VanDerWaalsContact O-N 3.13Å; F188-S191 WeakPolarHBondContact O-CB 3.38Å; F188-S191 PolarHBondContact O-N 2.94Å; F188-S191 VanDerWaalsContact O-N 3.11Å; F188-S191 PolarHBondContact O-OG 3.41Å; S189-S191 VanDerWaalsContact C-N 3.3Å; S189-S191 PolarHBondContact O-N 3.13Å; S191-A194 WeakPolarHBondContact O-CB 3.33Å; S191-A194 PolarHBondContact O-N 3.19Å; S191-A194 VanDerWaalsContact O-N 3.17Å; S191-R195 PolarHBondContact O-N 3.35Å; S191-N201 PolarHBondContact OG-ND2 3.43Å
192	V	98.3	Very high	97.2	Very high	0 Å²	0	26 Å²	26	0%	0	14%	0.143	C	C	.	.	H	α-helix	trans	-65.1	-39.5	175.1	173.8	0	0	0	0	111.5	F93 F188 S189 L190 A194 R195 L199 V245 P248 F249	F93-V192 WeakPolarHBondContact CD1-O 3.06Å; F93-V192 WeakPolarHBondContact CE1-O 3.23Å; F188-V192 PolarHBondContact O-N 3.06Å; S189-V192 WeakPolarHBondContact O-CB 3.34Å; S189-V192 PolarHBondContact O-N 3.42Å; S189-V192 VanDerWaalsContact O-N 3.12Å; L190-V192 VanDerWaalsContact C-N 3.34Å; V192-A194 PolarHBondContact O-N 2.99Å; V192-R195 VanDerWaalsContact CA-O 3.31Å; V192-R195 WeakPolarHBondContact CA-O 3.28Å; V192-R195 CarbonylContact O-C 3.53Å; V192-R195 PolarHBondContact O-N 2.95Å; V192-L199 HydrophobicContact CG1-CD2 4.04Å; V192-L199 HydrophobicContact CG1-CG 4.37Å; V192-L199 HydrophobicContact CG2-CD2 4.01Å; V192-L199 HydrophobicContact CG2-CG 4.29Å; V192-V245 HydrophobicContact CG2-CG1 3.74Å; V192-V245 WeakPolarHBondContact CG2-O 3.04Å; V192-P248 HydrophobicContact CG1-CB 4.27Å; V192-F249 HydrophobicContact CG1-CB 3.66Å
193	A	97.6	Very high	97.1	Very high	17 Å²	17	24.3 Å²	24.3	14%	0.14	13%	0.13	C	C	.	.	H	α-helix	trans	-63.4	-26.4	175.7	0	0	0	0	0	112.6	F93 F95 S189 L190 P248	F93-A193 WeakPolarHBondContact CB-O 3.33Å; F95-A193 VanDerWaalsContact CB-C 3.45Å; F95-A193 HydrophobicContact CB-CB 3.96Å; F95-A193 WeakPolarHBondContact CB-O 3.49Å; F95-A193 HydrophobicContact CD1-CB 4.06Å; F95-A193 HydrophobicContact CG-CB 4.2Å; F95-A193 PolarHBondContact N-O 2.91Å; S189-A193 PolarHBondContact O-N 2.91Å; L190-A193 PolarHBondContact O-N 3.07Å; A193-P248 HydrophobicContact CB-CB 3.98Å
194	A	96.1	Very high	97	Very high	1 Å²	1	21.2 Å²	21.2	1%	0.008	12%	0.115	C	C	.	.	H	α-helix	trans	-81.8	-40.2	173.1	0	0	0	0	0	112.8	F93 F95 S160 L163 F164 L190 S191 V192	F93-A194 WeakPolarHBondContact CB-O 3.49Å; F95-A194 HydrophobicContact CD1-CB 4.03Å; S160-A194 WeakPolarHBondContact CB-O 3.42Å; S160-A194 PolarHBondContact OG-O 3.07Å; L163-A194 HydrophobicContact CB-CB 4.36Å; F164-A194 HydrophobicContact CB-CB 4Å; L190-A194 PolarHBondContact O-N 3.25Å; S191-A194 WeakPolarHBondContact O-CB 3.33Å; S191-A194 PolarHBondContact O-N 3.19Å; S191-A194 VanDerWaalsContact O-N 3.17Å; V192-A194 PolarHBondContact O-N 2.99Å
195	R	95.7	Very high	96.9	Very high	36 Å²	36	21.4 Å²	21.4	14%	0.136	12%	0.116	C	C	.	.			trans	-154.7	140.3	-177.4	-60.2	-178.2	77.3	93.8	-16.4	111.6	S160 E161 F164 S191 V192 N197 G198	S160-R195 WeakPolarHBondContact OG-CG 3.4Å; S160-R195 PolarHBondContact OG-NH1 3.32Å; E161-R195 VanDerWaalsContact CD-CZ 3.42Å; E161-R195 IonicContact OE1-CZ 3.49Å; E161-R195 IonicContact OE1-NH1 3.83Å; E161-R195 PolarHBondContact OE1-NH1 3.09Å; E161-R195 IonicContact OE1-NH2 3.63Å; E161-R195 PolarHBondContact OE1-NH2 3.12Å; E161-R195 IonicContact OE2-CZ 3.94Å; E161-R195 IonicContact OE2-NH1 3.54Å; E161-R195 PolarHBondContact OE2-NH1 3.2Å; F164-R195 HydrophobicContact CB-CB 4.46Å; F164-R195 HydrophobicContact CB-CG 3.96Å; F164-R195 HydrophobicContact CD2-CB 4.01Å; F164-R195 HydrophobicContact CD2-CG 4.4Å; F164-R195 HydrophobicContact CG-CB 4.24Å; F164-R195 HydrophobicContact CG-CG 4.15Å; S191-R195 PolarHBondContact O-N 3.35Å; V192-R195 VanDerWaalsContact CA-O 3.31Å; V192-R195 WeakPolarHBondContact CA-O 3.28Å; V192-R195 CarbonylContact O-C 3.53Å; V192-R195 PolarHBondContact O-N 2.95Å; R195-N197 PolarHBondContact NE-ND2 3.32Å; R195-N197 PolarHBondContact O-N 3.48Å; R195-N197 VanDerWaalsContact O-N 3.12Å; R195-G198 PolarHBondContact O-N 3.29Å
196	S	94.9	Very high	96.8	Very high	15 Å²	15	26.6 Å²	26.6	11%	0.105	14%	0.138	C	C	.	.	G	3₁₀ helix	trans	-53.2	-33.2	173.7	55.7	0	0	0	0	113.7	G198 L199 Y304	S196-G198 PolarHBondContact O-N 3.21Å; S196-L199 WeakPolarHBondContact O-CB 3.46Å; S196-L199 VanDerWaalsContact O-CG 3.27Å; S196-L199 WeakPolarHBondContact O-CG 3.45Å; S196-L199 PolarHBondContact O-N 3.18Å; S196-Y304 PolarHBondContact OG-OH 3.47Å
197	N	93.8	Very high	96.5	Very high	27 Å²	27	23.6 Å²	23.6	14%	0.144	12%	0.121	C	C	.	.	G	3₁₀ helix	trans	-54.6	-25	177.9	-39.5	-19.9	0	0	0	113	F164 R195 L199 V200 L383	F164-N197 HydrophobicContact CE2-CB 4.46Å; F164-N197 HydrophobicContact CZ-CB 4.33Å; R195-N197 PolarHBondContact NE-ND2 3.32Å; R195-N197 PolarHBondContact O-N 3.48Å; R195-N197 VanDerWaalsContact O-N 3.12Å; N197-L199 PolarHBondContact O-N 3.12Å; N197-L199 VanDerWaalsContact O-N 3.11Å; N197-V200 WeakPolarHBondContact O-CG2 3.41Å; N197-V200 PolarHBondContact O-N 2.89Å; N197-V200 VanDerWaalsContact O-N 3.11Å; N197-L383 HydrophobicContact CB-CD1 4.2Å; N197-L383 WeakPolarHBondContact ND2-CD1 3.41Å
198	G	96.5	Very high	96.2	Very high	0 Å²	0	23.7 Å²	23.7	0%	0	12%	0.12	C	C	.	.	G	3₁₀ helix	trans	-60.7	-16.4	175.8	0	0	0	0	0	114.3	R195 S196 V200 N201	R195-G198 PolarHBondContact O-N 3.29Å; S196-G198 PolarHBondContact O-N 3.21Å; G198-V200 PolarHBondContact O-N 3.42Å; G198-N201 WeakPolarHBondContact O-CB 3.27Å; G198-N201 PolarHBondContact O-N 3.3Å
199	L	97.1	Very high	96	Very high	45 Å²	45	25 Å²	25	24%	0.236	13%	0.126	C	C	.	.	G	3₁₀ helix	trans	-61.2	-29.9	174.2	-68.5	174.1	0	0	0	111.8	V192 S196 N197 N201 I202 L246 F249	V192-L199 HydrophobicContact CG1-CD2 4.04Å; V192-L199 HydrophobicContact CG1-CG 4.37Å; V192-L199 HydrophobicContact CG2-CD2 4.01Å; V192-L199 HydrophobicContact CG2-CG 4.29Å; S196-L199 WeakPolarHBondContact O-CB 3.46Å; S196-L199 VanDerWaalsContact O-CG 3.27Å; S196-L199 WeakPolarHBondContact O-CG 3.45Å; S196-L199 PolarHBondContact O-N 3.18Å; N197-L199 PolarHBondContact O-N 3.12Å; N197-L199 VanDerWaalsContact O-N 3.11Å; L199-N201 PolarHBondContact O-N 2.72Å; L199-I202 WeakPolarHBondContact O-CB 3.36Å; L199-I202 VanDerWaalsContact O-CG1 3.29Å; L199-I202 WeakPolarHBondContact O-CG1 3.46Å; L199-I202 PolarHBondContact O-N 3.3Å; L199-I202 VanDerWaalsContact O-N 3.12Å; L199-L246 HydrophobicContact CD2-CD1 3.58Å; L199-F249 HydrophobicContact CD1-CD1 4.26Å; L199-F249 HydrophobicContact CD1-CD2 3.94Å; L199-F249 HydrophobicContact CD1-CE2 4.26Å; L199-F249 HydrophobicContact CD1-CG 3.98Å; L199-F249 HydrophobicContact CD2-CB 4.23Å
200	V	96.5	Very high	95.6	Very high	24 Å²	24	29.4 Å²	29.4	15%	0.145	14%	0.143	C	C	.	.	G	3₁₀ helix	trans	-65.2	-21.8	177.2	-167.8	0	0	0	0	111.3	N197 G198 I202 L203 H363 F366 L367	N197-V200 WeakPolarHBondContact O-CG2 3.41Å; N197-V200 PolarHBondContact O-N 2.89Å; N197-V200 VanDerWaalsContact O-N 3.11Å; G198-V200 PolarHBondContact O-N 3.42Å; V200-I202 PolarHBondContact O-N 3.27Å; V200-I202 VanDerWaalsContact O-N 3.09Å; V200-L203 VanDerWaalsContact O-CB 3.22Å; V200-L203 WeakPolarHBondContact O-CB 3.4Å; V200-L203 PolarHBondContact O-N 2.69Å; V200-H363 WeakPolarHBondContact CG1-CD2 3.35Å; V200-F366 HydrophobicContact CB-CD1 4.49Å; V200-F366 HydrophobicContact CG1-CD1 3.64Å; V200-F366 HydrophobicContact CG1-CE1 4.08Å; V200-F366 HydrophobicContact CG1-CG 4.46Å; V200-F366 HydrophobicContact CG2-CD1 3.9Å; V200-F366 HydrophobicContact CG2-CE1 3.57Å; V200-L367 HydrophobicContact CG2-CD2 3.98Å
201	N	96.6	Very high	95	Very high	0 Å²	0	27.7 Å²	27.7	0%	0	13%	0.134	C	C	.	.	G	3₁₀ helix	trans	-63.8	-16	175.4	-65.7	-29.5	0	0	0	113.3	S168 F188 S191 G198 L199 L203 F204	S168-N201 PolarHBondContact OG-ND2 3.4Å; S168-N201 VanDerWaalsContact OG-ND2 3.07Å; F188-N201 HydrophobicContact CB-CB 4.17Å; F188-N201 HydrophobicContact CD1-CB 3.59Å; F188-N201 HydrophobicContact CD2-CB 4.3Å; F188-N201 HydrophobicContact CE1-CB 3.96Å; F188-N201 HydrophobicContact CG-CB 3.78Å; F188-N201 HydrophobicContact CZ-CB 4.48Å; S191-N201 PolarHBondContact OG-ND2 3.43Å; G198-N201 WeakPolarHBondContact O-CB 3.27Å; G198-N201 PolarHBondContact O-N 3.3Å; L199-N201 PolarHBondContact O-N 2.72Å; N201-L203 PolarHBondContact O-N 3.41Å; N201-F204 HydrophobicContact CB-CD2 3.98Å; N201-F204 HydrophobicContact CB-CE2 4.37Å; N201-F204 WeakPolarHBondContact O-CB 3.43Å; N201-F204 WeakPolarHBondContact O-CD2 3.43Å; N201-F204 PolarHBondContact O-N 3.48Å; N201-F204 VanDerWaalsContact OD1-CE2 3.3Å; N201-F204 WeakPolarHBondContact OD1-CE2 3.49Å
202	I	97.1	Very high	94.5	Very high	47 Å²	47	30.7 Å²	30.7	24%	0.241	15%	0.15	C	C	.	.	H	α-helix	trans	-57.9	-30.8	171.3	-65.8	172.7	0	0	0	111.1	L199 V200 F204 L205 F206 A242 V245	L199-I202 WeakPolarHBondContact O-CB 3.36Å; L199-I202 VanDerWaalsContact O-CG1 3.29Å; L199-I202 WeakPolarHBondContact O-CG1 3.46Å; L199-I202 PolarHBondContact O-N 3.3Å; L199-I202 VanDerWaalsContact O-N 3.12Å; V200-I202 PolarHBondContact O-N 3.27Å; V200-I202 VanDerWaalsContact O-N 3.09Å; I202-F204 PolarHBondContact O-N 3.07Å; I202-L205 WeakPolarHBondContact O-CB 3.27Å; I202-L205 PolarHBondContact O-N 3.48Å; I202-F206 PolarHBondContact O-N 3.21Å; I202-A242 HydrophobicContact CG2-CB 3.94Å; I202-V245 HydrophobicContact CD1-CB 4.32Å; I202-V245 HydrophobicContact CD1-CG1 4.16Å; I202-V245 HydrophobicContact CG1-CB 3.91Å; I202-V245 HydrophobicContact CG1-CG1 3.66Å
203	L	95.5	Very high	93.9	Very high	46 Å²	46	31.6 Å²	31.6	24%	0.241	16%	0.155	C	C	.	.	H	α-helix	trans	-57.4	-34.6	175.6	-177.6	61.5	0	0	0	112.1	V200 N201 F206 F207 L359 L362 H363	V200-L203 VanDerWaalsContact O-CB 3.22Å; V200-L203 WeakPolarHBondContact O-CB 3.4Å; V200-L203 PolarHBondContact O-N 2.69Å; N201-L203 PolarHBondContact O-N 3.41Å; L203-F206 PolarHBondContact O-N 3.34Å; L203-F207 WeakPolarHBondContact O-CB 3.45Å; L203-F207 PolarHBondContact O-N 3Å; L203-L359 HydrophobicContact CD1-CD1 4.39Å; L203-L359 HydrophobicContact CD2-CD1 4.19Å; L203-L359 HydrophobicContact CG-CD1 3.81Å; L203-L362 HydrophobicContact CD1-CD2 4.26Å; L203-L362 HydrophobicContact CD2-CD2 4.09Å; L203-L362 HydrophobicContact CD2-CG 4.08Å; L203-H363 HydrophobicContact CD2-CB 4.19Å
204	F	96.1	Very high	93.1	Very high	0 Å²	0	35.6 Å²	35.6	0%	0	17%	0.169	C	C	.	.	H	α-helix	trans	-65.2	-40.1	175.9	-60.6	-56.6	0	0	0	111.9	M172 L175 F176 F188 N201 I202 F207 Y208 L359 L360 H363	M172-F204 HydrophobicContact CE-CD2 4.36Å; M172-F204 HydrophobicContact CE-CE2 3.53Å; M172-F204 HydrophobicContact CE-CZ 3.64Å; L175-F204 HydrophobicContact CD2-CB 3.69Å; L175-F204 WeakPolarHBondContact CD2-O 3.39Å; F176-F204 HydrophobicContact CE2-CD1 4.31Å; F176-F204 HydrophobicContact CZ-CB 4.25Å; F176-F204 AromaticContact CZ-CD1 3.94Å; F176-F204 HydrophobicContact CZ-CD1 3.94Å; F176-F204 HydrophobicContact CZ-CG 4.4Å; F188-F204 HydrophobicContact CE1-CD2 4.28Å; F188-F204 HydrophobicContact CE2-CB 4.21Å; F188-F204 HydrophobicContact CZ-CB 4.11Å; F188-F204 AromaticContact CZ-CD2 3.99Å; F188-F204 HydrophobicContact CZ-CD2 3.99Å; F188-F204 HydrophobicContact CZ-CG 4.39Å; N201-F204 HydrophobicContact CB-CD2 3.98Å; N201-F204 HydrophobicContact CB-CE2 4.37Å; N201-F204 WeakPolarHBondContact O-CB 3.43Å; N201-F204 WeakPolarHBondContact O-CD2 3.43Å; N201-F204 PolarHBondContact O-N 3.48Å; N201-F204 VanDerWaalsContact OD1-CE2 3.3Å; N201-F204 WeakPolarHBondContact OD1-CE2 3.49Å; I202-F204 PolarHBondContact O-N 3.07Å; F204-F207 PolarHBondContact O-N 3.23Å; F204-Y208 WeakPolarHBondContact O-CB 3.28Å; F204-Y208 PolarHBondContact O-N 3.21Å; F204-L359 HydrophobicContact CD1-CD2 3.5Å; F204-L359 VanDerWaalsContact CD1-CD2 3.5Å; F204-L359 HydrophobicContact CD1-CG 3.79Å; F204-L359 HydrophobicContact CE1-CD2 4.08Å; F204-L359 HydrophobicContact CE1-CG 3.95Å; F204-L360 HydrophobicContact CE1-CD2 3.83Å; F204-L360 HydrophobicContact CZ-CD2 3.99Å; F204-H363 HydrophobicContact CE1-CB 4.33Å; F204-H363 AromaticContact CE2-CD2 3.63Å; F204-H363 AromaticContact CE2-NE2 3.72Å; F204-H363 HydrophobicContact CZ-CB 4.06Å; F204-H363 AromaticContact CZ-CD2 3.47Å; F204-H363 VanDerWaalsContact CZ-CD2 3.47Å; F204-H363 WeakPolarHBondContact CZ-CD2 3.49Å; F204-H363 AromaticContact CZ-CG 3.66Å; F204-H363 AromaticContact CZ-NE2 3.88Å
205	L	97	Very high	92.2	Very high	4 Å²	4	39.2 Å²	39.2	2%	0.021	19%	0.194	C	C	.	.	H	α-helix	trans	-66.4	-42.1	176	-62.9	176.5	0	0	0	111.6	L175 A185 F188 I202 Y208 F209 L238 R241 V245	L175-L205 HydrophobicContact CD1-CD2 3.88Å; L175-L205 HydrophobicContact CD2-CD2 4.37Å; A185-L205 HydrophobicContact CB-CD1 4.19Å; F188-L205 HydrophobicContact CD2-CD2 4.34Å; F188-L205 HydrophobicContact CD2-CG 4.3Å; F188-L205 HydrophobicContact CE2-CD2 4.23Å; F188-L205 HydrophobicContact CE2-CG 4.37Å; I202-L205 WeakPolarHBondContact O-CB 3.27Å; I202-L205 PolarHBondContact O-N 3.48Å; L205-Y208 PolarHBondContact O-N 3.08Å; L205-F209 PolarHBondContact O-N 2.9Å; L205-L238 HydrophobicContact CB-CD1 3.93Å; L205-R241 HydrophobicContact CD1-CB 4.02Å; L205-V245 HydrophobicContact CD1-CG2 3.88Å
206	F	95	Very high	90.8	Very high	109 Å²	109	47.2 Å²	47.2	48%	0.478	22%	0.224	S	C	.	.	H	α-helix	trans	-59.7	-46.7	176.2	-179.4	-95.5	0	0	0	111.4	I202 L203 Y208 F209 F210 L238	I202-F206 PolarHBondContact O-N 3.21Å; L203-F206 PolarHBondContact O-N 3.34Å; F206-Y208 PolarHBondContact O-N 3.27Å; F206-F209 WeakPolarHBondContact O-CB 3.36Å; F206-F209 PolarHBondContact O-N 2.92Å; F206-F210 PolarHBondContact O-N 3.43Å; F206-L238 HydrophobicContact CD2-CD2 3.98Å
207	F	92.9	Very high	89.1	Confident	30 Å²	30	52.9 Å²	52.9	13%	0.132	26%	0.261	C	S	.	.	H	α-helix	trans	-62.1	-43.4	175.8	171.7	-89.8	0	0	0	112.6	F176 L203 F204 F209 F210 Q211 N355 I356 L359	F176-F207 HydrophobicContact CE1-CD1 4.08Å; F176-F207 HydrophobicContact CE1-CE1 4.26Å; L203-F207 WeakPolarHBondContact O-CB 3.45Å; L203-F207 PolarHBondContact O-N 3Å; F204-F207 PolarHBondContact O-N 3.23Å; F207-F209 VanDerWaalsContact C-N 3.29Å; F207-F209 PolarHBondContact O-N 3.43Å; F207-F210 PolarHBondContact O-N 2.96Å; F207-F210 VanDerWaalsContact O-N 3.16Å; F207-Q211 HydrophobicContact CE1-CB 4.41Å; F207-Q211 VanDerWaalsContact CE1-OE1 3.31Å; F207-Q211 WeakPolarHBondContact O-CB 3.32Å; F207-Q211 PolarHBondContact O-N 3.19Å; F207-N355 HydrophobicContact CE2-CB 3.76Å; F207-N355 HydrophobicContact CZ-CB 3.45Å; F207-N355 VanDerWaalsContact CZ-CB 3.45Å; F207-I356 HydrophobicContact CE1-CG1 3.81Å; F207-I356 HydrophobicContact CZ-CG1 4.19Å; F207-L359 HydrophobicContact CB-CD1 3.58Å; F207-L359 HydrophobicContact CB-CD2 3.49Å; F207-L359 VanDerWaalsContact CB-CD2 3.49Å; F207-L359 HydrophobicContact CB-CG 4.12Å; F207-L359 HydrophobicContact CD1-CD2 3.35Å; F207-L359 HydrophobicContact CD2-CB 4.22Å; F207-L359 HydrophobicContact CD2-CD1 4.06Å; F207-L359 HydrophobicContact CD2-CD2 3.94Å; F207-L359 HydrophobicContact CD2-CG 4.32Å; F207-L359 HydrophobicContact CE1-CD2 4.03Å; F207-L359 HydrophobicContact CE2-CB 4.46Å; F207-L359 HydrophobicContact CG-CB 4.38Å; F207-L359 HydrophobicContact CG-CD1 3.91Å; F207-L359 HydrophobicContact CG-CD2 3.3Å; F207-L359 HydrophobicContact CG-CG 4.07Å
208	Y	92.6	Very high	87.5	Confident	24 Å²	24	55.5 Å²	55.5	9%	0.094	27%	0.271	C	S	.	.	H	α-helix	trans	-59.5	-42.8	177.3	-176.7	-88.6	0	0	0	111.3	L175 P181 F204 L205 F206 Q211 D212	L175-Y208 HydrophobicContact CD1-CD1 4.17Å; L175-Y208 HydrophobicContact CD1-CD2 3.7Å; L175-Y208 HydrophobicContact CD1-CE2 4.3Å; L175-Y208 HydrophobicContact CD1-CG 3.62Å; L175-Y208 HydrophobicContact CG-CD2 3.86Å; L175-Y208 HydrophobicContact CG-CG 4.13Å; L175-Y208 WeakPolarHBondContact O-CE2 3.28Å; P181-Y208 HydrophobicContact CB-CD1 4.2Å; P181-Y208 HydrophobicContact CB-CE1 4.1Å; P181-Y208 HydrophobicContact CG-CE1 3.97Å; F204-Y208 WeakPolarHBondContact O-CB 3.28Å; F204-Y208 PolarHBondContact O-N 3.21Å; L205-Y208 PolarHBondContact O-N 3.08Å; F206-Y208 PolarHBondContact O-N 3.27Å; Y208-Q211 PolarHBondContact O-N 3.09Å; Y208-D212 VanDerWaalsContact O-CB 3.26Å; Y208-D212 WeakPolarHBondContact O-CB 3.18Å; Y208-D212 PolarHBondContact O-N 3.18Å
209	F	92.8	Very high	85.2	Confident	29 Å²	29	62.8 Å²	62.8	13%	0.127	31%	0.307	C	S	.	.	H	α-helix	trans	-58	-49.4	172.8	161.6	-92.9	0	0	0	111.5	L205 F206 F207 Q211 D212 M213 L231 K234 L238	L205-F209 PolarHBondContact O-N 2.9Å; F206-F209 WeakPolarHBondContact O-CB 3.36Å; F206-F209 PolarHBondContact O-N 2.92Å; F207-F209 VanDerWaalsContact C-N 3.29Å; F207-F209 PolarHBondContact O-N 3.43Å; F209-Q211 PolarHBondContact O-N 3.33Å; F209-D212 PolarHBondContact O-N 3.36Å; F209-M213 VanDerWaalsContact O-CB 3.31Å; F209-M213 WeakPolarHBondContact O-CB 3.47Å; F209-M213 PolarHBondContact O-N 3.01Å; F209-L231 HydrophobicContact CZ-CD1 3.93Å; F209-K234 HydrophobicContact CD2-CB 3.84Å; F209-K234 HydrophobicContact CE2-CB 3.57Å; F209-L238 HydrophobicContact CB-CB 4.44Å; F209-L238 HydrophobicContact CB-CD1 4.23Å; F209-L238 HydrophobicContact CB-CD2 4Å; F209-L238 HydrophobicContact CB-CG 4.46Å; F209-L238 HydrophobicContact CD1-CD2 3.9Å; F209-L238 HydrophobicContact CD2-CB 4.23Å; F209-L238 HydrophobicContact CD2-CD2 4.29Å; F209-L238 HydrophobicContact CE1-CD2 4.47Å; F209-L238 HydrophobicContact CG-CB 4.4Å; F209-L238 HydrophobicContact CG-CD2 3.8Å
210	F	89.4	Confident	83.3	Confident	106 Å²	106	68.5 Å²	68.5	47%	0.465	34%	0.337	S	S	.	.	H	α-helix	trans	-61.2	-46.8	-179.4	-169.9	-91	0	0	0	111.3	F206 F207 D212 M213 F214	F206-F210 PolarHBondContact O-N 3.43Å; F207-F210 PolarHBondContact O-N 2.96Å; F207-F210 VanDerWaalsContact O-N 3.16Å; F210-D212 PolarHBondContact O-N 3.12Å; F210-M213 PolarHBondContact O-N 3.35Å; F210-F214 HydrophobicContact CD1-CD2 4Å; F210-F214 AromaticContact CD2-CD2 3.43Å; F210-F214 HydrophobicContact CD2-CD2 3.43Å; F210-F214 VanDerWaalsContact CD2-CD2 3.43Å; F210-F214 AromaticContact CD2-CE2 3.41Å; F210-F214 HydrophobicContact CD2-CE2 3.41Å; F210-F214 VanDerWaalsContact CD2-CE2 3.41Å; F210-F214 HydrophobicContact CE1-CB 4.44Å; F210-F214 AromaticContact CE1-CD2 3.94Å; F210-F214 HydrophobicContact CE1-CD2 3.94Å; F210-F214 HydrophobicContact CE1-CG 4.47Å; F210-F214 AromaticContact CE2-CD2 3.36Å; F210-F214 HydrophobicContact CE2-CD2 3.36Å; F210-F214 AromaticContact CE2-CE2 3.33Å; F210-F214 HydrophobicContact CE2-CE2 3.33Å; F210-F214 HydrophobicContact CE2-CG 4.33Å; F210-F214 HydrophobicContact CE2-CZ 4.25Å; F210-F214 AromaticContact CG-CD2 3.76Å; F210-F214 HydrophobicContact CG-CD2 3.76Å; F210-F214 HydrophobicContact CG-CE2 4.16Å; F210-F214 AromaticContact CZ-CD2 3.63Å; F210-F214 HydrophobicContact CZ-CD2 3.63Å; F210-F214 HydrophobicContact CZ-CE2 4.04Å; F210-F214 HydrophobicContact CZ-CG 4.22Å; F210-F214 VanDerWaalsContact O-CD2 3.25Å; F210-F214 WeakPolarHBondContact O-CD2 3.47Å; F210-F214 PolarHBondContact O-N 2.83Å
211	Q	86.8	Confident	81.4	Confident	22 Å²	22	77.5 Å²	77.5	10%	0.103	37%	0.368	C	S	.	.	H	α-helix	trans	-62.3	-42.5	177.8	-170.4	-178.6	-3.7	0	0	111.9	F207 Y208 F209 M213 S215 T352	F207-Q211 HydrophobicContact CE1-CB 4.41Å; F207-Q211 VanDerWaalsContact CE1-OE1 3.31Å; F207-Q211 WeakPolarHBondContact O-CB 3.32Å; F207-Q211 PolarHBondContact O-N 3.19Å; Y208-Q211 PolarHBondContact O-N 3.09Å; F209-Q211 PolarHBondContact O-N 3.33Å; Q211-M213 VanDerWaalsContact C-N 3.31Å; Q211-M213 PolarHBondContact O-N 3.31Å; Q211-S215 WeakPolarHBondContact O-CB 3.46Å; Q211-S215 PolarHBondContact O-N 3.11Å; Q211-S215 PolarHBondContact O-OG 3.49Å; Q211-T352 PolarHBondContact NE2-OG1 2.95Å
212	D	85.6	Confident	79.6	Confident	63 Å²	63	85 Å²	85	34%	0.337	40%	0.403	S	S	.	.	H	α-helix	trans	-70.7	-27.1	179	-170.5	56.2	0	0	0	112.7	Y208 F209 F210 K234	Y208-D212 VanDerWaalsContact O-CB 3.26Å; Y208-D212 WeakPolarHBondContact O-CB 3.18Å; Y208-D212 PolarHBondContact O-N 3.18Å; F209-D212 PolarHBondContact O-N 3.36Å; F210-D212 PolarHBondContact O-N 3.12Å; D212-K234 VanDerWaalsContact CG-NZ 3.33Å; D212-K234 PolarHBondContact O-NZ 2.93Å; D212-K234 IonicContact OD1-NZ 3.76Å; D212-K234 WeakPolarHBondContact OD2-CE 3.38Å; D212-K234 IonicContact OD2-NZ 3.83Å; D212-K234 PolarHBondContact OD2-NZ 2.99Å
213	M	85.2	Confident	78.6	Confident	19 Å²	19	89.8 Å²	89.8	9%	0.094	43%	0.428	C	S	.	.	H	α-helix	trans	-79.5	-43.3	177.4	-167.9	60.2	-159.7	0	0	112.6	F209 F210 Q211 F227 L231 K234	F209-M213 VanDerWaalsContact O-CB 3.31Å; F209-M213 WeakPolarHBondContact O-CB 3.47Å; F209-M213 PolarHBondContact O-N 3.01Å; F210-M213 PolarHBondContact O-N 3.35Å; Q211-M213 VanDerWaalsContact C-N 3.31Å; Q211-M213 PolarHBondContact O-N 3.31Å; M213-F227 HydrophobicContact CE-CD2 3.42Å; M213-F227 VanDerWaalsContact CE-CD2 3.42Å; M213-F227 HydrophobicContact CE-CE1 4.46Å; M213-F227 HydrophobicContact CE-CE2 3.05Å; M213-F227 HydrophobicContact CE-CG 4.32Å; M213-F227 HydrophobicContact CE-CZ 3.64Å; M213-L231 HydrophobicContact CE-CB 4.09Å; M213-L231 HydrophobicContact CE-CD1 4.37Å; M213-L231 HydrophobicContact CG-CD1 4.43Å; M213-L231 HydrophobicContact SD-CD1 4.49Å; M213-K234 HydrophobicContact SD-CD 3.89Å
214	F	81.9	Confident	77.9	Confident	100 Å²	100	89.6 Å²	89.6	44%	0.439	43%	0.431	S	S	.	.	H	α-helix	trans	-108.2	3.4	-169.1	-60.1	-74.2	0	0	0	114.8	F210 R216	F210-F214 HydrophobicContact CD1-CD2 4Å; F210-F214 AromaticContact CD2-CD2 3.43Å; F210-F214 HydrophobicContact CD2-CD2 3.43Å; F210-F214 VanDerWaalsContact CD2-CD2 3.43Å; F210-F214 AromaticContact CD2-CE2 3.41Å; F210-F214 HydrophobicContact CD2-CE2 3.41Å; F210-F214 VanDerWaalsContact CD2-CE2 3.41Å; F210-F214 HydrophobicContact CE1-CB 4.44Å; F210-F214 AromaticContact CE1-CD2 3.94Å; F210-F214 HydrophobicContact CE1-CD2 3.94Å; F210-F214 HydrophobicContact CE1-CG 4.47Å; F210-F214 AromaticContact CE2-CD2 3.36Å; F210-F214 HydrophobicContact CE2-CD2 3.36Å; F210-F214 AromaticContact CE2-CE2 3.33Å; F210-F214 HydrophobicContact CE2-CE2 3.33Å; F210-F214 HydrophobicContact CE2-CG 4.33Å; F210-F214 HydrophobicContact CE2-CZ 4.25Å; F210-F214 AromaticContact CG-CD2 3.76Å; F210-F214 HydrophobicContact CG-CD2 3.76Å; F210-F214 HydrophobicContact CG-CE2 4.16Å; F210-F214 AromaticContact CZ-CD2 3.63Å; F210-F214 HydrophobicContact CZ-CD2 3.63Å; F210-F214 HydrophobicContact CZ-CE2 4.04Å; F210-F214 HydrophobicContact CZ-CG 4.22Å; F210-F214 VanDerWaalsContact O-CD2 3.25Å; F210-F214 WeakPolarHBondContact O-CD2 3.47Å; F210-F214 PolarHBondContact O-N 2.83Å; F214-R216 VanDerWaalsContact C-N 3.28Å; F214-R216 PolarHBondContact O-N 3.05Å
215	S	76	Confident	77.5	Confident	78 Å²	78	96.6 Å²	96.6	55%	0.545	46%	0.463	S	S	.	.	S	Bend	trans	-71.2	-19.1	176.6	49.2	0	0	0	0	114.4	Q211	Q211-S215 WeakPolarHBondContact O-CB 3.46Å; Q211-S215 PolarHBondContact O-N 3.11Å; Q211-S215 PolarHBondContact O-OG 3.49Å
216	R	67.5	Low	76.9	Confident	203 Å²	203	100.3 Å²	100.3	77%	0.766	49%	0.489	S	S	*	.	S	Bend	trans	-86.1	133.3	172.6	-63.3	-172.5	-178	-167	-0.3	108.3	F214 F218	F214-R216 VanDerWaalsContact C-N 3.28Å; F214-R216 PolarHBondContact O-N 3.05Å; R216-F218 VanDerWaalsContact C-N 3.27Å; R216-F218 PolarHBondContact O-N 3.07Å
217	P	59.1	Low	76.4	Confident	135 Å²	135	96.7 Å²	96.7	88%	0.877	47%	0.474	S	S	*	.			trans	-61.9	95.4	176.3	24.4	-30.8	0	0	0	108.1	M219	P217-M219 PolarHBondContact O-N 3.11Å
218	F	59.2	Low	76.2	Confident	82 Å²	82	97.8 Å²	97.8	36%	0.36	48%	0.483	S	S	.	.			trans	-82.3	112.3	-179.6	-163.1	-99.7	0	0	0	106.5	R216 L220 F227	R216-F218 VanDerWaalsContact C-N 3.27Å; R216-F218 PolarHBondContact O-N 3.07Å; F218-L220 VanDerWaalsContact C-N 3.29Å; F218-L220 PolarHBondContact O-N 2.97Å; F218-F227 HydrophobicContact CD1-CD2 4.49Å; F218-F227 HydrophobicContact CD1-CE2 4.25Å; F218-F227 AromaticContact CD2-CD2 3.82Å; F218-F227 HydrophobicContact CD2-CD2 3.82Å; F218-F227 HydrophobicContact CD2-CE2 4.04Å; F218-F227 AromaticContact CE1-CD2 3.91Å; F218-F227 HydrophobicContact CE1-CD2 3.91Å; F218-F227 AromaticContact CE1-CE2 3.97Å; F218-F227 HydrophobicContact CE1-CE2 3.97Å; F218-F227 HydrophobicContact CE1-CG 4.21Å; F218-F227 HydrophobicContact CE1-CZ 4.42Å; F218-F227 HydrophobicContact CE2-CB 3.93Å; F218-F227 AromaticContact CE2-CD2 3.14Å; F218-F227 HydrophobicContact CE2-CD2 3.14Å; F218-F227 AromaticContact CE2-CE2 3.78Å; F218-F227 HydrophobicContact CE2-CE2 3.78Å; F218-F227 AromaticContact CE2-CG 3.77Å; F218-F227 HydrophobicContact CE2-CG 3.77Å; F218-F227 HydrophobicContact CG-CD2 4.46Å; F218-F227 HydrophobicContact CG-CE2 4.29Å; F218-F227 HydrophobicContact CZ-CB 3.68Å; F218-F227 HydrophobicContact CZ-CD1 4.18Å; F218-F227 AromaticContact CZ-CD2 3.2Å; F218-F227 HydrophobicContact CZ-CD2 3.2Å; F218-F227 AromaticContact CZ-CE2 3.74Å; F218-F227 HydrophobicContact CZ-CE2 3.74Å; F218-F227 AromaticContact CZ-CG 3.43Å; F218-F227 HydrophobicContact CZ-CG 3.43Å; F218-F227 VanDerWaalsContact CZ-CG 3.43Å; F218-F227 HydrophobicContact CZ-CZ 4.46Å
219	M	49.6	Very low	76.1	Confident	153 Å²	153	101.1 Å²	101.1	75%	0.754	50%	0.502	S	S	*	.			trans	-64.3	100.2	162.1	-94.9	-161.5	-68.6	0	0	106.7	P217 R221	P217-M219 PolarHBondContact O-N 3.11Å; M219-R221 PolarHBondContact O-N 3.32Å
220	L	57.5	Low	76	Confident	165 Å²	165	101.6 Å²	101.6	86%	0.864	51%	0.511	S	S	*	.	T	Hydrogen-bonded Turn	trans	-51	0.8	170.7	-88.8	154.5	0	0	0	114.5	F218 H222	F218-L220 VanDerWaalsContact C-N 3.29Å; F218-L220 PolarHBondContact O-N 2.97Å; L220-H222 PolarHBondContact O-N 2.76Å
221	R	55.3	Low	76.1	Confident	212 Å²	212	99.4 Å²	99.4	80%	0.8	50%	0.504	S	S	*	.	T	Hydrogen-bonded Turn	trans	-75	-18.3	-171.5	-94.5	-177.9	169.4	169.3	-3	114.8	M219	M219-R221 PolarHBondContact O-N 3.32Å
222	H	60	Low	76.4	Confident	159 Å²	159	103 Å²	103	74%	0.736	52%	0.524	S	S	*	.			trans	-149	128.6	168.4	-78.8	-67.8	0	0	0	112.8	L220 S224	L220-H222 PolarHBondContact O-N 2.76Å; H222-S224 PolarHBondContact O-N 2.99Å
223	L	74.4	Confident	76.8	Confident	146 Å²	146	109.8 Å²	109.8	76%	0.764	54%	0.544	S	S	*	.			trans	-64.3	83.3	160.4	-91.6	110.7	0	0	0	108.5	V228	L223-V228 HydrophobicContact CD2-CG2 3.99Å
224	S	82.4	Confident	77.2	Confident	42 Å²	42	111.7 Å²	111.7	29%	0.294	55%	0.552	S	S	.	*			trans	-68	145.6	173.2	71.5	0	0	0	0	109.9	H222 S226 F227 V228	H222-S224 PolarHBondContact O-N 2.99Å; S224-S226 PolarHBondContact O-N 2.89Å; S224-S226 VanDerWaalsContact O-N 3.16Å; S224-S226 PolarHBondContact OG-OG 3.36Å; S224-F227 WeakPolarHBondContact O-CB 3.37Å; S224-F227 PolarHBondContact O-N 2.86Å; S224-F227 WeakPolarHBondContact OG-CB 3.44Å; S224-F227 PolarHBondContact OG-N 2.91Å; S224-F227 VanDerWaalsContact OG-N 3.14Å; S224-V228 PolarHBondContact O-N 2.66Å
225	H	86.2	Confident	77.8	Confident	148 Å²	148	108.5 Å²	108.5	69%	0.685	54%	0.542	S	S	*	.	H	α-helix	trans	-52.9	-35.7	172.4	-179.7	-109.7	0	0	0	112	F227 V228 L229	H225-F227 PolarHBondContact O-N 2.94Å; H225-V228 PolarHBondContact O-N 3.11Å; H225-L229 WeakPolarHBondContact CE1-CD1 3.48Å; H225-L229 WeakPolarHBondContact ND1-CD1 3.45Å; H225-L229 WeakPolarHBondContact O-CB 3.42Å; H225-L229 PolarHBondContact O-N 3.37Å
226	S	85.6	Confident	78.8	Confident	81 Å²	81	110.3 Å²	110.3	57%	0.566	54%	0.544	S	S	*	.	H	α-helix	trans	-63.7	-37	175.4	53.9	0	0	0	0	113.6	S224 A230	S224-S226 PolarHBondContact O-N 2.89Å; S224-S226 VanDerWaalsContact O-N 3.16Å; S224-S226 PolarHBondContact OG-OG 3.36Å; S226-A230 WeakPolarHBondContact O-CB 3.37Å; S226-A230 PolarHBondContact O-N 3.43Å
227	F	84.9	Confident	80.2	Confident	33 Å²	33	102 Å²	102	15%	0.145	52%	0.518	C	S	.	.	H	α-helix	trans	-68	-45.3	175.3	173.8	-96.2	0	0	0	111.3	M213 F218 S224 H225 L229 A230 L231	M213-F227 HydrophobicContact CE-CD2 3.42Å; M213-F227 VanDerWaalsContact CE-CD2 3.42Å; M213-F227 HydrophobicContact CE-CE1 4.46Å; M213-F227 HydrophobicContact CE-CE2 3.05Å; M213-F227 HydrophobicContact CE-CG 4.32Å; M213-F227 HydrophobicContact CE-CZ 3.64Å; F218-F227 HydrophobicContact CD1-CD2 4.49Å; F218-F227 HydrophobicContact CD1-CE2 4.25Å; F218-F227 AromaticContact CD2-CD2 3.82Å; F218-F227 HydrophobicContact CD2-CD2 3.82Å; F218-F227 HydrophobicContact CD2-CE2 4.04Å; F218-F227 AromaticContact CE1-CD2 3.91Å; F218-F227 HydrophobicContact CE1-CD2 3.91Å; F218-F227 AromaticContact CE1-CE2 3.97Å; F218-F227 HydrophobicContact CE1-CE2 3.97Å; F218-F227 HydrophobicContact CE1-CG 4.21Å; F218-F227 HydrophobicContact CE1-CZ 4.42Å; F218-F227 HydrophobicContact CE2-CB 3.93Å; F218-F227 AromaticContact CE2-CD2 3.14Å; F218-F227 HydrophobicContact CE2-CD2 3.14Å; F218-F227 AromaticContact CE2-CE2 3.78Å; F218-F227 HydrophobicContact CE2-CE2 3.78Å; F218-F227 AromaticContact CE2-CG 3.77Å; F218-F227 HydrophobicContact CE2-CG 3.77Å; F218-F227 HydrophobicContact CG-CD2 4.46Å; F218-F227 HydrophobicContact CG-CE2 4.29Å; F218-F227 HydrophobicContact CZ-CB 3.68Å; F218-F227 HydrophobicContact CZ-CD1 4.18Å; F218-F227 AromaticContact CZ-CD2 3.2Å; F218-F227 HydrophobicContact CZ-CD2 3.2Å; F218-F227 AromaticContact CZ-CE2 3.74Å; F218-F227 HydrophobicContact CZ-CE2 3.74Å; F218-F227 AromaticContact CZ-CG 3.43Å; F218-F227 HydrophobicContact CZ-CG 3.43Å; F218-F227 VanDerWaalsContact CZ-CG 3.43Å; F218-F227 HydrophobicContact CZ-CZ 4.46Å; S224-F227 WeakPolarHBondContact O-CB 3.37Å; S224-F227 PolarHBondContact O-N 2.86Å; S224-F227 WeakPolarHBondContact OG-CB 3.44Å; S224-F227 PolarHBondContact OG-N 2.91Å; S224-F227 VanDerWaalsContact OG-N 3.14Å; H225-F227 PolarHBondContact O-N 2.94Å; F227-L229 PolarHBondContact O-N 3.21Å; F227-A230 PolarHBondContact O-N 3.16Å; F227-L231 HydrophobicContact CE1-CD2 4.3Å; F227-L231 WeakPolarHBondContact O-CB 3.16Å; F227-L231 PolarHBondContact O-N 3.24Å
228	V	88.3	Confident	82	Confident	54 Å²	54	96.8 Å²	96.8	33%	0.327	48%	0.482	S	S	.	.	H	α-helix	trans	-60.7	-46	178.8	177.7	0	0	0	0	110.7	L223 S224 H225 A230 L231 L232	L223-V228 HydrophobicContact CD2-CG2 3.99Å; S224-V228 PolarHBondContact O-N 2.66Å; H225-V228 PolarHBondContact O-N 3.11Å; V228-A230 PolarHBondContact O-N 3.32Å; V228-L231 PolarHBondContact O-N 3.21Å; V228-L232 HydrophobicContact CG1-CD1 4.06Å; V228-L232 HydrophobicContact CG1-CG 4.47Å; V228-L232 WeakPolarHBondContact O-CB 3.36Å; V228-L232 WeakPolarHBondContact O-CG 3.24Å; V228-L232 PolarHBondContact O-N 3.02Å
229	L	90.5	Very high	83.8	Confident	93 Å²	93	98.3 Å²	98.3	49%	0.487	49%	0.493	S	S	.	.	H	α-helix	trans	-60.1	-43.2	174.6	-80.8	166.7	0	0	0	112.6	H225 F227 L232 R233	H225-L229 WeakPolarHBondContact CE1-CD1 3.48Å; H225-L229 WeakPolarHBondContact ND1-CD1 3.45Å; H225-L229 WeakPolarHBondContact O-CB 3.42Å; H225-L229 PolarHBondContact O-N 3.37Å; F227-L229 PolarHBondContact O-N 3.21Å; L229-L232 PolarHBondContact O-N 3.11Å; L229-R233 WeakPolarHBondContact O-CB 3.36Å; L229-R233 PolarHBondContact O-N 3.39Å
230	A	89.6	Confident	86.1	Confident	39 Å²	39	94 Å²	94	32%	0.322	48%	0.478	S	S	.	.	H	α-helix	trans	-64.1	-43.1	177	0	0	0	0	0	111.7	S226 F227 V228 R233 K234	S226-A230 WeakPolarHBondContact O-CB 3.37Å; S226-A230 PolarHBondContact O-N 3.43Å; F227-A230 PolarHBondContact O-N 3.16Å; V228-A230 PolarHBondContact O-N 3.32Å; A230-R233 PolarHBondContact O-N 3.11Å; A230-K234 WeakPolarHBondContact O-CB 3.3Å; A230-K234 VanDerWaalsContact O-CG 3.31Å; A230-K234 WeakPolarHBondContact O-CG 3.43Å; A230-K234 PolarHBondContact O-N 2.95Å
231	L	91.5	Very high	88	Confident	60 Å²	60	88.7 Å²	88.7	31%	0.314	45%	0.446	S	S	.	.	H	α-helix	trans	-61.5	-48.5	176.8	179.5	62.7	0	0	0	111	F209 M213 F227 V228 K234 S235	F209-L231 HydrophobicContact CZ-CD1 3.93Å; M213-L231 HydrophobicContact CE-CB 4.09Å; M213-L231 HydrophobicContact CE-CD1 4.37Å; M213-L231 HydrophobicContact CG-CD1 4.43Å; M213-L231 HydrophobicContact SD-CD1 4.49Å; F227-L231 HydrophobicContact CE1-CD2 4.3Å; F227-L231 WeakPolarHBondContact O-CB 3.16Å; F227-L231 PolarHBondContact O-N 3.24Å; V228-L231 PolarHBondContact O-N 3.21Å; L231-K234 PolarHBondContact O-N 3.46Å; L231-S235 WeakPolarHBondContact O-CB 3.35Å; L231-S235 PolarHBondContact O-N 2.59Å; L231-S235 PolarHBondContact O-OG 3.47Å
232	L	94	Very high	90.1	Very high	99 Å²	99	79.6 Å²	79.6	52%	0.518	42%	0.416	S	S	.	.	H	α-helix	trans	-59.5	-50.6	176.9	-74.1	171.3	0	0	0	111.2	V228 L229 K234 S235 I236	V228-L232 HydrophobicContact CG1-CD1 4.06Å; V228-L232 HydrophobicContact CG1-CG 4.47Å; V228-L232 WeakPolarHBondContact O-CB 3.36Å; V228-L232 WeakPolarHBondContact O-CG 3.24Å; V228-L232 PolarHBondContact O-N 3.02Å; L229-L232 PolarHBondContact O-N 3.11Å; L232-K234 PolarHBondContact O-N 3.45Å; L232-S235 PolarHBondContact O-N 3.47Å; L232-I236 VanDerWaalsContact O-CG1 3.3Å; L232-I236 WeakPolarHBondContact O-CG1 3.21Å; L232-I236 PolarHBondContact O-N 2.9Å
233	R	94.1	Very high	91.9	Very high	204 Å²	204	74.2 Å²	74.2	77%	0.77	40%	0.4	S	S	*	.	H	α-helix	trans	-59.9	-45.2	179.9	-177.4	177.3	175.5	162.5	0.7	112.2	L229 A230 S237	L229-R233 WeakPolarHBondContact O-CB 3.36Å; L229-R233 PolarHBondContact O-N 3.39Å; A230-R233 PolarHBondContact O-N 3.11Å; R233-S237 WeakPolarHBondContact O-CB 3.29Å; R233-S237 PolarHBondContact O-N 3.46Å
234	K	93.3	Very high	93	Very high	59 Å²	59	69.5 Å²	69.5	26%	0.257	38%	0.377	S	S	.	.	H	α-helix	trans	-69.2	-35	178.4	-70.4	-170.2	-171.1	-163.1	0	111.8	F209 D212 M213 A230 L231 L232 S237 L238	F209-K234 HydrophobicContact CD2-CB 3.84Å; F209-K234 HydrophobicContact CE2-CB 3.57Å; D212-K234 VanDerWaalsContact CG-NZ 3.33Å; D212-K234 PolarHBondContact O-NZ 2.93Å; D212-K234 IonicContact OD1-NZ 3.76Å; D212-K234 WeakPolarHBondContact OD2-CE 3.38Å; D212-K234 IonicContact OD2-NZ 3.83Å; D212-K234 PolarHBondContact OD2-NZ 2.99Å; M213-K234 HydrophobicContact SD-CD 3.89Å; A230-K234 WeakPolarHBondContact O-CB 3.3Å; A230-K234 VanDerWaalsContact O-CG 3.31Å; A230-K234 WeakPolarHBondContact O-CG 3.43Å; A230-K234 PolarHBondContact O-N 2.95Å; L231-K234 PolarHBondContact O-N 3.46Å; L232-K234 PolarHBondContact O-N 3.45Å; K234-S237 CarbonylContact O-C 3.22Å; K234-S237 PolarHBondContact O-N 2.82Å; K234-L238 PolarHBondContact O-N 3.25Å
235	S	95.5	Very high	93.8	Very high	34 Å²	34	67.5 Å²	67.5	24%	0.238	36%	0.363	C	S	.	.	H	α-helix	trans	-67.5	-45.7	176.9	-59.1	0	0	0	0	111.5	L231 L232 S237 L238 I239	L231-S235 WeakPolarHBondContact O-CB 3.35Å; L231-S235 PolarHBondContact O-N 2.59Å; L231-S235 PolarHBondContact O-OG 3.47Å; L232-S235 PolarHBondContact O-N 3.47Å; S235-S237 PolarHBondContact O-N 3.39Å; S235-L238 WeakPolarHBondContact O-CB 3.39Å; S235-L238 PolarHBondContact O-N 2.7Å; S235-I239 WeakPolarHBondContact O-CG1 3.49Å; S235-I239 PolarHBondContact O-N 3.01Å
236	I	96.7	Very high	94.4	Very high	115 Å²	115	63.4 Å²	63.4	59%	0.59	35%	0.345	S	S	*	.	H	α-helix	trans	-57.3	-43.1	172.6	-67.6	165.3	0	0	0	110	L232 L238 I239 S240	L232-I236 VanDerWaalsContact O-CG1 3.3Å; L232-I236 WeakPolarHBondContact O-CG1 3.21Å; L232-I236 PolarHBondContact O-N 2.9Å; I236-L238 VanDerWaalsContact C-N 3.33Å; I236-L238 PolarHBondContact O-N 3.38Å; I236-I239 PolarHBondContact O-N 3.04Å; I236-S240 WeakPolarHBondContact O-CB 3.21Å; I236-S240 PolarHBondContact O-N 3.12Å; I236-S240 PolarHBondContact O-OG 3.49Å
237	S	96.1	Very high	94.9	Very high	30 Å²	30	63.2 Å²	63.2	21%	0.21	34%	0.338	C	S	.	.	H	α-helix	trans	-67.4	-29.7	177.2	-175.2	0	0	0	0	114	R233 K234 S235 S240 R241	R233-S237 WeakPolarHBondContact O-CB 3.29Å; R233-S237 PolarHBondContact O-N 3.46Å; K234-S237 CarbonylContact O-C 3.22Å; K234-S237 PolarHBondContact O-N 2.82Å; S235-S237 PolarHBondContact O-N 3.39Å; S237-S240 PolarHBondContact O-OG 2.98Å; S237-R241 VanDerWaalsContact O-CD 3.31Å; S237-R241 WeakPolarHBondContact O-CD 3.37Å; S237-R241 WeakPolarHBondContact O-CG 3.41Å; S237-R241 PolarHBondContact O-N 3.46Å; S237-R241 PolarHBondContact OG-NE 3.2Å; S237-R241 PolarHBondContact OG-NH1 2.89Å; S237-R241 PolarHBondContact OG-NH2 3.38Å
238	L	97.1	Very high	95.6	Very high	24 Å²	24	63.1 Å²	63.1	13%	0.126	34%	0.34	C	S	.	.	H	α-helix	trans	-71.8	-49	173.6	170.8	64	0	0	0	110	L205 F206 F209 K234 S235 I236 S240 R241 A242	L205-L238 HydrophobicContact CB-CD1 3.93Å; F206-L238 HydrophobicContact CD2-CD2 3.98Å; F209-L238 HydrophobicContact CB-CB 4.44Å; F209-L238 HydrophobicContact CB-CD1 4.23Å; F209-L238 HydrophobicContact CB-CD2 4Å; F209-L238 HydrophobicContact CB-CG 4.46Å; F209-L238 HydrophobicContact CD1-CD2 3.9Å; F209-L238 HydrophobicContact CD2-CB 4.23Å; F209-L238 HydrophobicContact CD2-CD2 4.29Å; F209-L238 HydrophobicContact CE1-CD2 4.47Å; F209-L238 HydrophobicContact CG-CB 4.4Å; F209-L238 HydrophobicContact CG-CD2 3.8Å; K234-L238 PolarHBondContact O-N 3.25Å; S235-L238 WeakPolarHBondContact O-CB 3.39Å; S235-L238 PolarHBondContact O-N 2.7Å; I236-L238 VanDerWaalsContact C-N 3.33Å; I236-L238 PolarHBondContact O-N 3.38Å; L238-S240 VanDerWaalsContact C-N 3.33Å; L238-S240 PolarHBondContact O-N 2.77Å; L238-R241 PolarHBondContact O-N 3.18Å; L238-A242 WeakPolarHBondContact O-CB 3.36Å; L238-A242 PolarHBondContact O-N 3.32Å
239	I	97.5	Very high	96	Very high	115 Å²	115	61.3 Å²	61.3	59%	0.59	33%	0.328	S	S	*	.	H	α-helix	trans	-59.3	-45.5	-179.8	-67.4	165.8	0	0	0	110.2	S235 I236 R241 A242 A243	S235-I239 WeakPolarHBondContact O-CG1 3.49Å; S235-I239 PolarHBondContact O-N 3.01Å; I236-I239 PolarHBondContact O-N 3.04Å; I239-R241 PolarHBondContact O-N 3.18Å; I239-A242 PolarHBondContact O-N 2.96Å; I239-A243 WeakPolarHBondContact O-CB 3Å; I239-A243 PolarHBondContact O-N 3.29Å
240	S	97.8	Very high	96.3	Very high	61 Å²	61	60.7 Å²	60.7	43%	0.427	33%	0.325	S	S	.	.	H	α-helix	trans	-62.6	-41.2	178.8	67.2	0	0	0	0	112.5	I236 S237 L238 A243 V244	I236-S240 WeakPolarHBondContact O-CB 3.21Å; I236-S240 PolarHBondContact O-N 3.12Å; I236-S240 PolarHBondContact O-OG 3.49Å; S237-S240 PolarHBondContact O-OG 2.98Å; L238-S240 VanDerWaalsContact C-N 3.33Å; L238-S240 PolarHBondContact O-N 2.77Å; S240-A243 PolarHBondContact O-N 2.98Å; S240-V244 WeakPolarHBondContact O-CG2 3.4Å; S240-V244 PolarHBondContact O-N 3.2Å
241	R	98.1	Very high	96.6	Very high	54 Å²	54	65.1 Å²	65.1	20%	0.204	34%	0.337	C	S	.	.	H	α-helix	trans	-69.1	-40.3	176.7	-70.9	172.2	-171.1	144.3	6.1	112.3	P181 T182 A185 L205 S237 L238 I239 A243 V244 V245	P181-R241 VanDerWaalsContact CG-NH1 3.33Å; T182-R241 PolarHBondContact OG1-NE 3.18Å; A185-R241 HydrophobicContact CB-CB 3.84Å; A185-R241 HydrophobicContact CB-CG 4.13Å; L205-R241 HydrophobicContact CD1-CB 4.02Å; S237-R241 VanDerWaalsContact O-CD 3.31Å; S237-R241 WeakPolarHBondContact O-CD 3.37Å; S237-R241 WeakPolarHBondContact O-CG 3.41Å; S237-R241 PolarHBondContact O-N 3.46Å; S237-R241 PolarHBondContact OG-NE 3.2Å; S237-R241 PolarHBondContact OG-NH1 2.89Å; S237-R241 PolarHBondContact OG-NH2 3.38Å; L238-R241 PolarHBondContact O-N 3.18Å; I239-R241 PolarHBondContact O-N 3.18Å; R241-A243 VanDerWaalsContact C-N 3.32Å; R241-V244 WeakPolarHBondContact O-CB 3.36Å; R241-V244 PolarHBondContact O-N 3.23Å; R241-V245 WeakPolarHBondContact O-CG2 3.43Å; R241-V245 PolarHBondContact O-N 3.27Å; R241-V245 VanDerWaalsContact O-N 3.12Å
242	A	98.3	Very high	96.9	Very high	21 Å²	21	62.7 Å²	62.7	17%	0.174	32%	0.324	C	S	.	.	H	α-helix	trans	-63.5	-39.9	174.7	0	0	0	0	0	111.2	I202 L238 I239 V244 V245 L246	I202-A242 HydrophobicContact CG2-CB 3.94Å; L238-A242 WeakPolarHBondContact O-CB 3.36Å; L238-A242 PolarHBondContact O-N 3.32Å; I239-A242 PolarHBondContact O-N 2.96Å; A242-V244 PolarHBondContact O-N 3.21Å; A242-V245 PolarHBondContact O-N 3.02Å; A242-L246 PolarHBondContact O-N 3.22Å
243	A	98.1	Very high	97	Very high	47 Å²	47	58.6 Å²	58.6	39%	0.388	30%	0.302	S	S	.	.	H	α-helix	trans	-60	-45.3	173.2	0	0	0	0	0	111.2	I239 S240 R241 V245 L246 L247	I239-A243 WeakPolarHBondContact O-CB 3Å; I239-A243 PolarHBondContact O-N 3.29Å; S240-A243 PolarHBondContact O-N 2.98Å; R241-A243 VanDerWaalsContact C-N 3.32Å; A243-V245 VanDerWaalsContact C-N 3.27Å; A243-V245 PolarHBondContact O-N 3.42Å; A243-L246 PolarHBondContact O-N 3.46Å; A243-L247 WeakPolarHBondContact O-CG 3.37Å; A243-L247 PolarHBondContact O-N 2.85Å
244	V	98.3	Very high	97	Very high	46 Å²	46	54 Å²	54	28%	0.279	29%	0.293	S	S	.	.	H	α-helix	trans	-56.5	-39.8	174.8	169	0	0	0	0	112.4	A185 L186 S189 S240 R241 A242	A185-V244 HydrophobicContact CB-CG1 4.44Å; L186-V244 HydrophobicContact CD2-CG1 3.82Å; S189-V244 VanDerWaalsContact CB-O 3.25Å; S189-V244 WeakPolarHBondContact CB-O 3.47Å; S240-V244 WeakPolarHBondContact O-CG2 3.4Å; S240-V244 PolarHBondContact O-N 3.2Å; R241-V244 WeakPolarHBondContact O-CB 3.36Å; R241-V244 PolarHBondContact O-N 3.23Å; A242-V244 PolarHBondContact O-N 3.21Å
245	V	98.6	Very high	97.1	Very high	0 Å²	0	55.2 Å²	55.2	0%	0	30%	0.298	C	S	.	.	H	α-helix	trans	-67.3	-37.9	176.1	178.2	0	0	0	0	111.6	A185 F188 V192 I202 L205 R241 A242 A243 P248	A185-V245 HydrophobicContact CB-CG2 4.14Å; A185-V245 WeakPolarHBondContact O-CG2 3.47Å; F188-V245 HydrophobicContact CB-CG1 4.14Å; F188-V245 HydrophobicContact CB-CG2 3.77Å; V192-V245 HydrophobicContact CG2-CG1 3.74Å; V192-V245 WeakPolarHBondContact CG2-O 3.04Å; I202-V245 HydrophobicContact CD1-CB 4.32Å; I202-V245 HydrophobicContact CD1-CG1 4.16Å; I202-V245 HydrophobicContact CG1-CB 3.91Å; I202-V245 HydrophobicContact CG1-CG1 3.66Å; L205-V245 HydrophobicContact CD1-CG2 3.88Å; R241-V245 WeakPolarHBondContact O-CG2 3.43Å; R241-V245 PolarHBondContact O-N 3.27Å; R241-V245 VanDerWaalsContact O-N 3.12Å; A242-V245 PolarHBondContact O-N 3.02Å; A243-V245 VanDerWaalsContact C-N 3.27Å; A243-V245 PolarHBondContact O-N 3.42Å; V245-P248 WeakPolarHBondContact O-CD 3.45Å
246	L	97.8	Very high	97.1	Very high	62 Å²	62	53.6 Å²	53.6	33%	0.325	29%	0.287	S	S	.	.	H	α-helix	trans	-74.9	-27.4	-179	-177.5	62.1	0	0	0	113.4	L199 A242 A243 F249 L250	L199-L246 HydrophobicContact CD2-CD1 3.58Å; A242-L246 PolarHBondContact O-N 3.22Å; A243-L246 PolarHBondContact O-N 3.46Å; L246-F249 HydrophobicContact CD1-CB 4.43Å; L246-F249 HydrophobicContact CD1-CD1 4.26Å; L246-F249 WeakPolarHBondContact O-CB 3.19Å; L246-F249 PolarHBondContact O-N 3.46Å; L246-F249 VanDerWaalsContact O-N 3.1Å; L246-L250 HydrophobicContact CD1-CG 4.37Å; L246-L250 HydrophobicContact CD2-CD1 4Å; L246-L250 HydrophobicContact CD2-CG 4.43Å; L246-L250 HydrophobicContact CG-CD1 3.88Å; L246-L250 HydrophobicContact CG-CD2 4.47Å; L246-L250 HydrophobicContact CG-CG 3.93Å; L246-L250 PolarHBondContact O-N 3.39Å
247	L	97.5	Very high	97	Very high	77 Å²	77	51.3 Å²	51.3	40%	0.403	27%	0.271	S	S	.	.	H	α-helix	trans	-51.4	-49.1	-173.4	-81.3	174.9	0	0	0	114.5	A243 F249 L250 F251	A243-L247 WeakPolarHBondContact O-CG 3.37Å; A243-L247 PolarHBondContact O-N 2.85Å; L247-F249 PolarHBondContact O-N 3.39Å; L247-L250 PolarHBondContact O-N 3.14Å; L247-L250 VanDerWaalsContact O-N 3.16Å; L247-F251 HydrophobicContact CB-CD2 4.21Å; L247-F251 HydrophobicContact CB-CE2 4.18Å; L247-F251 HydrophobicContact CD2-CD2 4.46Å; L247-F251 HydrophobicContact CD2-CE2 3.86Å; L247-F251 HydrophobicContact CG-CE2 4.44Å; L247-F251 VanDerWaalsContact O-CD2 3.23Å; L247-F251 WeakPolarHBondContact O-CD2 3.31Å; L247-F251 PolarHBondContact O-N 3.16Å
248	P	97.8	Very high	96.8	Very high	31 Å²	31	55.9 Å²	55.9	20%	0.201	28%	0.284	C	S	.	.	H	α-helix	trans	-60.5	-34	-178.7	-25.3	36.8	0	0	0	113.2	S189 V192 A193 V245 Y252	S189-P248 WeakPolarHBondContact O-CG 3.24Å; V192-P248 HydrophobicContact CG1-CB 4.27Å; A193-P248 HydrophobicContact CB-CB 3.98Å; V245-P248 WeakPolarHBondContact O-CD 3.45Å; P248-Y252 VanDerWaalsContact O-CB 3.23Å; P248-Y252 WeakPolarHBondContact O-CB 3.33Å; P248-Y252 PolarHBondContact O-N 2.81Å
249	F	97.3	Very high	96.6	Very high	16 Å²	16	56.6 Å²	56.6	7%	0.07	29%	0.285	C	S	.	.	H	α-helix	trans	-65.7	-48	176.1	-177.6	-96	0	0	0	111.2	F93 V192 L199 L246 L247 Y252 Q253 F302	F93-F249 AromaticContact CE1-CD2 3.8Å; F93-F249 HydrophobicContact CE1-CD2 3.8Å; F93-F249 HydrophobicContact CE1-CE2 4.43Å; F93-F249 AromaticContact CZ-CD2 3.5Å; F93-F249 HydrophobicContact CZ-CD2 3.5Å; F93-F249 VanDerWaalsContact CZ-CD2 3.5Å; F93-F249 AromaticContact CZ-CE2 3.68Å; F93-F249 HydrophobicContact CZ-CE2 3.68Å; V192-F249 HydrophobicContact CG1-CB 3.66Å; L199-F249 HydrophobicContact CD1-CD1 4.26Å; L199-F249 HydrophobicContact CD1-CD2 3.94Å; L199-F249 HydrophobicContact CD1-CE2 4.26Å; L199-F249 HydrophobicContact CD1-CG 3.98Å; L199-F249 HydrophobicContact CD2-CB 4.23Å; L246-F249 HydrophobicContact CD1-CB 4.43Å; L246-F249 HydrophobicContact CD1-CD1 4.26Å; L246-F249 WeakPolarHBondContact O-CB 3.19Å; L246-F249 PolarHBondContact O-N 3.46Å; L246-F249 VanDerWaalsContact O-N 3.1Å; L247-F249 PolarHBondContact O-N 3.39Å; F249-Y252 PolarHBondContact O-N 2.98Å; F249-Q253 HydrophobicContact CD1-CG 4.31Å; F249-Q253 HydrophobicContact CE1-CG 3.93Å; F249-Q253 HydrophobicContact CZ-CG 4Å; F249-Q253 WeakPolarHBondContact O-CG 3.35Å; F249-Q253 PolarHBondContact O-N 3.22Å; F249-F302 AromaticContact CE1-CE2 3.55Å; F249-F302 HydrophobicContact CE1-CE2 3.55Å; F249-F302 AromaticContact CE1-CZ 3.78Å; F249-F302 HydrophobicContact CE1-CZ 3.78Å; F249-F302 AromaticContact CZ-CE2 3.58Å; F249-F302 HydrophobicContact CZ-CE2 3.58Å; F249-F302 AromaticContact CZ-CZ 3.45Å; F249-F302 HydrophobicContact CZ-CZ 3.45Å; F249-F302 VanDerWaalsContact CZ-CZ 3.45Å
250	L	96.8	Very high	96.3	Very high	80 Å²	80	51.3 Å²	51.3	42%	0.419	26%	0.257	S	S	.	.	H	α-helix	trans	-64.4	-46.2	179.3	-62.8	177.1	0	0	0	111.8	L246 L247 Y252 Q253 L254	L246-L250 HydrophobicContact CD1-CG 4.37Å; L246-L250 HydrophobicContact CD2-CD1 4Å; L246-L250 HydrophobicContact CD2-CG 4.43Å; L246-L250 HydrophobicContact CG-CD1 3.88Å; L246-L250 HydrophobicContact CG-CD2 4.47Å; L246-L250 HydrophobicContact CG-CG 3.93Å; L246-L250 PolarHBondContact O-N 3.39Å; L247-L250 PolarHBondContact O-N 3.14Å; L247-L250 VanDerWaalsContact O-N 3.16Å; L250-Y252 VanDerWaalsContact C-N 3.28Å; L250-Y252 PolarHBondContact O-N 3.39Å; L250-Q253 PolarHBondContact O-N 2.9Å; L250-L254 WeakPolarHBondContact O-CB 3.24Å; L250-L254 WeakPolarHBondContact O-CG 3.26Å; L250-L254 PolarHBondContact O-N 2.99Å
251	F	96.8	Very high	96	Very high	133 Å²	133	49.4 Å²	49.4	58%	0.583	24%	0.244	S	C	*	.	H	α-helix	trans	-59.8	-41	176.3	-80.3	-59.6	0	0	0	111.8	L247 L254 F255	L247-F251 HydrophobicContact CB-CD2 4.21Å; L247-F251 HydrophobicContact CB-CE2 4.18Å; L247-F251 HydrophobicContact CD2-CD2 4.46Å; L247-F251 HydrophobicContact CD2-CE2 3.86Å; L247-F251 HydrophobicContact CG-CE2 4.44Å; L247-F251 VanDerWaalsContact O-CD2 3.23Å; L247-F251 WeakPolarHBondContact O-CD2 3.31Å; L247-F251 PolarHBondContact O-N 3.16Å; F251-L254 PolarHBondContact O-N 3.42Å; F251-F255 VanDerWaalsContact O-CB 3.32Å; F251-F255 WeakPolarHBondContact O-CB 3.17Å; F251-F255 PolarHBondContact O-N 3.42Å
252	Y	97	Very high	95.7	Very high	8 Å²	8	52 Å²	52	3%	0.031	26%	0.261	C	S	.	.	H	α-helix	trans	-65.4	-44.1	177.1	178.3	-119.7	0	0	0	112.4	Y84 A90 F92 F93 P94 P248 F249 L250 L254 F255 I256	Y84-Y252 HydrophobicContact CE1-CE2 4.24Å; Y84-Y252 VanDerWaalsContact CE1-OH 3.32Å; Y84-Y252 WeakPolarHBondContact CE1-OH 3.26Å; Y84-Y252 HydrophobicContact CE2-CE2 4.36Å; Y84-Y252 AromaticContact CZ-CE2 3.78Å; Y84-Y252 WeakPolarHBondContact OH-CE2 3.28Å; Y84-Y252 PolarHBondContact OH-OH 2.96Å; A90-Y252 WeakPolarHBondContact CA-OH 3.41Å; A90-Y252 PolarHBondContact O-OH 3.12Å; F92-Y252 PolarHBondContact O-OH 3.42Å; F93-Y252 HydrophobicContact CD1-CD1 4.08Å; F93-Y252 HydrophobicContact CD1-CE1 4.48Å; F93-Y252 HydrophobicContact CD2-CD1 4.16Å; F93-Y252 AromaticContact CD2-CE1 3.81Å; F93-Y252 HydrophobicContact CD2-CE1 3.81Å; F93-Y252 AromaticContact CE1-CD1 3.88Å; F93-Y252 HydrophobicContact CE1-CD1 3.88Å; F93-Y252 HydrophobicContact CE1-CE1 4.49Å; F93-Y252 AromaticContact CE2-CD1 3.95Å; F93-Y252 HydrophobicContact CE2-CD1 3.95Å; F93-Y252 AromaticContact CE2-CE1 3.8Å; F93-Y252 HydrophobicContact CE2-CE1 3.8Å; F93-Y252 HydrophobicContact CG-CD1 4.21Å; F93-Y252 HydrophobicContact CG-CE1 4.15Å; F93-Y252 AromaticContact CZ-CD1 3.79Å; F93-Y252 HydrophobicContact CZ-CD1 3.79Å; F93-Y252 HydrophobicContact CZ-CE1 4.14Å; P94-Y252 HydrophobicContact CB-CD2 4.22Å; P94-Y252 HydrophobicContact CB-CE2 4.25Å; P94-Y252 VanDerWaalsContact CD-CD2 3.49Å; P94-Y252 HydrophobicContact CG-CD2 3.61Å; P94-Y252 HydrophobicContact CG-CE2 4.04Å; P94-Y252 HydrophobicContact CG-CG 4.19Å; P248-Y252 VanDerWaalsContact O-CB 3.23Å; P248-Y252 WeakPolarHBondContact O-CB 3.33Å; P248-Y252 PolarHBondContact O-N 2.81Å; F249-Y252 PolarHBondContact O-N 2.98Å; L250-Y252 VanDerWaalsContact C-N 3.28Å; L250-Y252 PolarHBondContact O-N 3.39Å; Y252-L254 VanDerWaalsContact C-N 3.34Å; Y252-L254 PolarHBondContact O-N 3.24Å; Y252-F255 HydrophobicContact CD2-CD1 4.21Å; Y252-F255 HydrophobicContact CE2-CD1 4.34Å; Y252-F255 WeakPolarHBondContact O-CB 3.49Å; Y252-F255 PolarHBondContact O-N 2.99Å; Y252-I256 HydrophobicContact CD2-CG1 4.09Å; Y252-I256 HydrophobicContact CE1-CG1 4.17Å; Y252-I256 HydrophobicContact CE2-CD1 3.72Å; Y252-I256 HydrophobicContact CE2-CG1 3.59Å; Y252-I256 WeakPolarHBondContact O-CG1 3.2Å; Y252-I256 PolarHBondContact O-N 3.2Å
253	Q	96	Very high	95	Very high	14 Å²	14	52.7 Å²	52.7	7%	0.065	27%	0.265	C	S	.	.	H	α-helix	trans	-61.8	-42.6	176.3	-69.9	-60.9	-66.3	0	0	111.8	F249 L250 I256 Y257 F302 S303	F249-Q253 HydrophobicContact CD1-CG 4.31Å; F249-Q253 HydrophobicContact CE1-CG 3.93Å; F249-Q253 HydrophobicContact CZ-CG 4Å; F249-Q253 WeakPolarHBondContact O-CG 3.35Å; F249-Q253 PolarHBondContact O-N 3.22Å; L250-Q253 PolarHBondContact O-N 2.9Å; Q253-I256 PolarHBondContact O-N 3.25Å; Q253-Y257 WeakPolarHBondContact O-CB 3.32Å; Q253-Y257 PolarHBondContact O-N 2.8Å; Q253-F302 HydrophobicContact CG-CD2 4.34Å; Q253-F302 HydrophobicContact CG-CE2 4.02Å; Q253-S303 PolarHBondContact OE1-OG 3.27Å; Q253-S303 VanDerWaalsContact OE1-OG 3.1Å
254	L	95.4	Very high	93.9	Very high	108 Å²	108	53.8 Å²	53.8	57%	0.565	27%	0.269	S	S	*	.	H	α-helix	trans	-63.5	-40.7	174.7	-70.4	172.2	0	0	0	112.1	L250 F251 Y252 Y257 W258	L250-L254 WeakPolarHBondContact O-CB 3.24Å; L250-L254 WeakPolarHBondContact O-CG 3.26Å; L250-L254 PolarHBondContact O-N 2.99Å; F251-L254 PolarHBondContact O-N 3.42Å; Y252-L254 VanDerWaalsContact C-N 3.34Å; Y252-L254 PolarHBondContact O-N 3.24Å; L254-Y257 PolarHBondContact O-N 3.38Å; L254-W258 WeakPolarHBondContact O-CB 3.33Å; L254-W258 PolarHBondContact O-N 3.28Å
255	F	95.2	Very high	92.8	Very high	84 Å²	84	52.5 Å²	52.5	37%	0.368	26%	0.262	S	S	.	.	H	α-helix	trans	-61.8	-46.5	176	165.4	-99.3	0	0	0	111.9	Y84 F251 Y252 W258 R259	Y84-F255 AromaticContact CD2-CE1 3.59Å; Y84-F255 HydrophobicContact CD2-CE1 3.59Å; Y84-F255 HydrophobicContact CD2-CZ 4.07Å; Y84-F255 AromaticContact CE2-CE1 3.74Å; Y84-F255 HydrophobicContact CE2-CE1 3.74Å; Y84-F255 HydrophobicContact CE2-CZ 4.45Å; Y84-F255 HydrophobicContact CG-CE1 4.43Å; F251-F255 VanDerWaalsContact O-CB 3.32Å; F251-F255 WeakPolarHBondContact O-CB 3.17Å; F251-F255 PolarHBondContact O-N 3.42Å; Y252-F255 HydrophobicContact CD2-CD1 4.21Å; Y252-F255 HydrophobicContact CE2-CD1 4.34Å; Y252-F255 WeakPolarHBondContact O-CB 3.49Å; Y252-F255 PolarHBondContact O-N 2.99Å; F255-W258 PolarHBondContact O-N 3.11Å; F255-R259 VanDerWaalsContact O-CB 3.25Å; F255-R259 WeakPolarHBondContact O-CB 3.31Å; F255-R259 PolarHBondContact O-N 2.64Å
256	I	94.8	Very high	91.5	Very high	0 Å²	0	54 Å²	54	0%	0	27%	0.274	C	S	.	.	H	α-helix	trans	-64.1	-43.5	177.5	-68.4	-57	0	0	0	111	Y84 A90 Y252 Q253 R259 F260 W295 S303	Y84-I256 HydrophobicContact CD1-CD1 3.89Å; Y84-I256 HydrophobicContact CD2-CD1 4.33Å; Y84-I256 HydrophobicContact CE1-CD1 4.14Å; Y84-I256 HydrophobicContact CG-CD1 3.98Å; A90-I256 HydrophobicContact CB-CD1 3.69Å; A90-I256 HydrophobicContact CB-CG1 4.01Å; A90-I256 HydrophobicContact CB-CG2 3.72Å; Y252-I256 HydrophobicContact CD2-CG1 4.09Å; Y252-I256 HydrophobicContact CE1-CG1 4.17Å; Y252-I256 HydrophobicContact CE2-CD1 3.72Å; Y252-I256 HydrophobicContact CE2-CG1 3.59Å; Y252-I256 WeakPolarHBondContact O-CG1 3.2Å; Y252-I256 PolarHBondContact O-N 3.2Å; Q253-I256 PolarHBondContact O-N 3.25Å; I256-R259 PolarHBondContact O-N 2.96Å; I256-F260 HydrophobicContact CD1-CE2 4.5Å; I256-F260 HydrophobicContact CG2-CD2 4.06Å; I256-F260 PolarHBondContact O-N 3.13Å; I256-W295 HydrophobicContact CG2-CH2 3.77Å; I256-W295 HydrophobicContact CG2-CZ2 4.3Å; I256-W295 HydrophobicContact CG2-CZ3 4.49Å; I256-S303 WeakPolarHBondContact CG2-OG 3.19Å
257	Y	94.2	Very high	90	Very high	67 Å²	67	60.5 Å²	60.5	26%	0.263	30%	0.303	S	S	.	.	H	α-helix	trans	-59.3	-48.7	175.1	174.5	-110	0	0	0	111.8	Q253 L254 R259 C261 L262 W295 P301	Q253-Y257 WeakPolarHBondContact O-CB 3.32Å; Q253-Y257 PolarHBondContact O-N 2.8Å; L254-Y257 PolarHBondContact O-N 3.38Å; Y257-R259 VanDerWaalsContact C-N 3.32Å; Y257-R259 PolarHBondContact O-N 2.94Å; Y257-C261 HydrophobicContact CD2-CB 3.69Å; Y257-C261 WeakPolarHBondContact CD2-SG 3.5Å; Y257-C261 HydrophobicContact CE2-CB 3.57Å; Y257-C261 WeakPolarHBondContact O-CA 3.46Å; Y257-C261 WeakPolarHBondContact O-CB 3.48Å; Y257-C261 PolarHBondContact O-N 3.34Å; Y257-L262 HydrophobicContact CD1-CD1 4.1Å; Y257-L262 HydrophobicContact CD1-CG 4.35Å; Y257-L262 HydrophobicContact CE1-CD1 3.66Å; Y257-L262 HydrophobicContact CE1-CD2 4.15Å; Y257-L262 HydrophobicContact CE1-CG 3.86Å; Y257-W295 HydrophobicContact CD2-CZ3 4.12Å; Y257-P301 HydrophobicContact CD1-CG 4.43Å; Y257-P301 HydrophobicContact CD2-CB 3.44Å; Y257-P301 VanDerWaalsContact CD2-CB 3.44Å; Y257-P301 HydrophobicContact CD2-CG 3.47Å; Y257-P301 VanDerWaalsContact CD2-CG 3.47Å; Y257-P301 HydrophobicContact CE1-CG 4.42Å; Y257-P301 HydrophobicContact CE2-CB 3.5Å; Y257-P301 VanDerWaalsContact CE2-CB 3.5Å; Y257-P301 HydrophobicContact CE2-CG 3.47Å; Y257-P301 VanDerWaalsContact CE2-CG 3.47Å; Y257-P301 HydrophobicContact CG-CB 4.35Å; Y257-P301 HydrophobicContact CG-CG 3.98Å
258	W	93	Very high	88.7	Confident	125 Å²	125	64 Å²	64	47%	0.473	32%	0.317	S	S	.	.	I	π-helix	trans	-59.2	-44.9	176.3	175.5	78.8	0	0	0	111.7	L254 F255 L262 S263	L254-W258 WeakPolarHBondContact O-CB 3.33Å; L254-W258 PolarHBondContact O-N 3.28Å; F255-W258 PolarHBondContact O-N 3.11Å; W258-L262 PolarHBondContact O-N 2.86Å; W258-S263 PolarHBondContact O-N 3.05Å
259	R	91.6	Very high	87.7	Confident	40 Å²	40	63 Å²	63	15%	0.151	31%	0.31	C	S	.	.	I	π-helix	trans	-69.6	-37.3	-176.3	-177.3	59.6	179.4	-175.7	6.5	113.6	F255 I256 Y257 S263 L287	F255-R259 VanDerWaalsContact O-CB 3.25Å; F255-R259 WeakPolarHBondContact O-CB 3.31Å; F255-R259 PolarHBondContact O-N 2.64Å; I256-R259 PolarHBondContact O-N 2.96Å; Y257-R259 VanDerWaalsContact C-N 3.32Å; Y257-R259 PolarHBondContact O-N 2.94Å; R259-S263 CarbonylContact C-O 3.58Å; R259-L287 HydrophobicContact CG-CD1 3.93Å; R259-L287 WeakPolarHBondContact O-CD1 3.05Å
260	F	92.1	Very high	86.7	Confident	3 Å²	3	64.8 Å²	64.8	1%	0.013	33%	0.332	C	S	.	.	I	π-helix	trans	-97	-33.1	-176.6	-82.3	-94.4	0	0	0	113.5	F86 E87 A90 I256 L287 L293 W295	F86-F260 WeakPolarHBondContact O-CZ 3.37Å; E87-F260 HydrophobicContact CB-CE1 4.28Å; A90-F260 HydrophobicContact CB-CE2 4.38Å; I256-F260 HydrophobicContact CD1-CE2 4.5Å; I256-F260 HydrophobicContact CG2-CD2 4.06Å; I256-F260 PolarHBondContact O-N 3.13Å; F260-L287 HydrophobicContact CD1-CD1 4.15Å; F260-L287 HydrophobicContact CD2-CD1 4.46Å; F260-L287 HydrophobicContact CE1-CD1 4.23Å; F260-L287 HydrophobicContact CG-CD1 4.26Å; F260-L287 HydrophobicContact CZ-CD1 4.43Å; F260-L293 HydrophobicContact CB-CD1 4.13Å; F260-L293 HydrophobicContact CD1-CD1 4.05Å; F260-L293 HydrophobicContact CD1-CD2 4.46Å; F260-W295 HydrophobicContact CB-CH2 3.72Å; F260-W295 HydrophobicContact CB-CZ2 3.83Å; F260-W295 HydrophobicContact CG-CH2 4.4Å; F260-W295 HydrophobicContact CG-CZ2 4.22Å
261	C	92.1	Very high	86.1	Confident	22 Å²	22	65.1 Å²	65.1	15%	0.149	33%	0.334	C	S	.	.	I	π-helix	trans	-103.4	-31.2	-171.4	-48.8	0	0	0	0	113.9	Y257 L290 W295 C296	Y257-C261 HydrophobicContact CD2-CB 3.69Å; Y257-C261 WeakPolarHBondContact CD2-SG 3.5Å; Y257-C261 HydrophobicContact CE2-CB 3.57Å; Y257-C261 WeakPolarHBondContact O-CA 3.46Å; Y257-C261 WeakPolarHBondContact O-CB 3.48Å; Y257-C261 PolarHBondContact O-N 3.34Å; C261-L290 HydrophobicContact CB-CD1 4.23Å; C261-W295 VanDerWaalsContact SG-CH2 3.51Å; C261-W295 WeakPolarHBondContact SG-CZ3 3.07Å; C261-C296 HydrophobicContact CB-CB 3.72Å; C261-C296 WeakPolarHBondContact CB-SG 3.39Å; C261-C296 VanDerWaalsContact SG-CA 3.53Å; C261-C296 WeakPolarHBondContact SG-CB 3.26Å; C261-C296 CovalentContact SG-SG 2.03Å; C261-C296 PolarHBondContact SG-SG 3.13Å
262	L	90.3	Very high	85.6	Confident	108 Å²	108	62.5 Å²	62.5	57%	0.565	32%	0.321	S	S	*	.	I	π-helix	trans	-107.6	-42.8	-173	-59.6	-177.5	0	0	0	113.8	Y257 W258	Y257-L262 HydrophobicContact CD1-CD1 4.1Å; Y257-L262 HydrophobicContact CD1-CG 4.35Å; Y257-L262 HydrophobicContact CE1-CD1 3.66Å; Y257-L262 HydrophobicContact CE1-CD2 4.15Å; Y257-L262 HydrophobicContact CE1-CG 3.86Å; W258-L262 PolarHBondContact O-N 2.86Å
263	S	84.5	Confident	85.1	Confident	36 Å²	36	66.3 Å²	66.3	25%	0.252	35%	0.349	S	S	.	.			trans	-118.4	106.9	-174.3	-174.4	0	0	0	0	109.5	W258 R259 P265	W258-S263 PolarHBondContact O-N 3.05Å; R259-S263 CarbonylContact C-O 3.58Å; S263-P265 VanDerWaalsContact C-CD 3.42Å; S263-P265 WeakPolarHBondContact O-CD 3.48Å
264	C	75.9	Confident	84.9	Confident	70 Å²	70	68.3 Å²	68.3	47%	0.473	36%	0.36	S	S	.	.			trans	-108.1	86.2	179.6	159.9	0	0	0	0	110.2	A266 C288	C264-A266 PolarHBondContact O-N 2.92Å; C264-C288 VanDerWaalsContact CA-SG 3.52Å; C264-C288 HydrophobicContact CB-CB 3.88Å; C264-C288 WeakPolarHBondContact CB-SG 3.49Å; C264-C288 WeakPolarHBondContact SG-CB 3.31Å; C264-C288 CovalentContact SG-SG 1.98Å; C264-C288 PolarHBondContact SG-SG 3.45Å
265	P	73.7	Confident	84.7	Confident	19 Å²	19	63.8 Å²	63.8	12%	0.123	34%	0.335	C	S	.	.			trans	-86.5	67.6	171.5	33.1	-33.3	0	0	0	109.6	S263 E267 E268	S263-P265 VanDerWaalsContact C-CD 3.42Å; S263-P265 WeakPolarHBondContact O-CD 3.48Å; P265-E267 PolarHBondContact O-N 2.77Å; P265-E268 HydrophobicContact CB-CB 3.97Å; P265-E268 VanDerWaalsContact CB-CD 3.45Å; P265-E268 HydrophobicContact CB-CG 3.72Å; P265-E268 WeakPolarHBondContact CB-OE2 3.41Å; P265-E268 PolarHBondContact O-N 2.84Å
266	A	71.2	Confident	84.5	Confident	31 Å²	31	63.4 Å²	63.4	26%	0.256	33%	0.333	S	S	.	.	T	Hydrogen-bonded Turn	trans	-57.3	-35.6	173.9	0	0	0	0	0	111.3	C264 E268 L269 Y272	C264-A266 PolarHBondContact O-N 2.92Å; A266-E268 VanDerWaalsContact C-N 3.34Å; A266-E268 PolarHBondContact O-N 2.8Å; A266-L269 WeakPolarHBondContact O-CB 3.25Å; A266-L269 PolarHBondContact O-N 3.49Å; A266-Y272 HydrophobicContact CB-CD2 4.45Å; A266-Y272 HydrophobicContact CB-CE2 4.23Å
267	E	67.4	Low	84.4	Confident	199 Å²	199	66 Å²	66	93%	0.93	36%	0.355	S	S	*	.	T	Hydrogen-bonded Turn	trans	-68.2	-28.5	179.6	-63.8	-176.7	175.6	0	0	113.4	P265 L269	P265-E267 PolarHBondContact O-N 2.77Å; E267-L269 PolarHBondContact O-N 3.34Å
268	E	69.9	Low	84.4	Confident	149 Å²	149	63.9 Å²	63.9	70%	0.696	35%	0.347	S	S	*	.	T	Hydrogen-bonded Turn	trans	-75	-16.2	175.5	-66.2	178.5	175	0	0	112.3	P265 A266 G270	P265-E268 HydrophobicContact CB-CB 3.97Å; P265-E268 VanDerWaalsContact CB-CD 3.45Å; P265-E268 HydrophobicContact CB-CG 3.72Å; P265-E268 WeakPolarHBondContact CB-OE2 3.41Å; P265-E268 PolarHBondContact O-N 2.84Å; A266-E268 VanDerWaalsContact C-N 3.34Å; A266-E268 PolarHBondContact O-N 2.8Å; E268-G270 VanDerWaalsContact C-N 3.27Å; E268-G270 PolarHBondContact O-N 2.76Å
269	L	77.1	Confident	84.4	Confident	12 Å²	12	58 Å²	58	6%	0.063	33%	0.325	C	S	.	.	S	Bend	trans	-79.9	79.3	179.2	-148.2	77.4	0	0	0	109.6	V82 T85 A266 E267 N271 Y272 Y275 L286	V82-L269 HydrophobicContact CG1-CD1 4.38Å; T85-L269 HydrophobicContact CG2-CD1 3.49Å; T85-L269 VanDerWaalsContact CG2-CD1 3.49Å; T85-L269 HydrophobicContact CG2-CD2 4.23Å; T85-L269 HydrophobicContact CG2-CG 4.41Å; A266-L269 WeakPolarHBondContact O-CB 3.25Å; A266-L269 PolarHBondContact O-N 3.49Å; E267-L269 PolarHBondContact O-N 3.34Å; L269-N271 PolarHBondContact O-N 3.28Å; L269-Y272 HydrophobicContact CB-CD2 4.35Å; L269-Y272 HydrophobicContact CD2-CD2 4.13Å; L269-Y272 WeakPolarHBondContact O-CA 3.34Å; L269-Y272 WeakPolarHBondContact O-CB 3.46Å; L269-Y272 PolarHBondContact O-N 3.37Å; L269-Y275 HydrophobicContact CD2-CD2 3.5Å; L269-Y275 HydrophobicContact CD2-CE2 4.2Å; L269-Y275 HydrophobicContact CD2-CG 4.24Å; L269-Y275 HydrophobicContact CG-CD2 3.83Å; L269-Y275 HydrophobicContact CG-CE2 4.05Å; L269-L286 HydrophobicContact CD2-CD1 4.47Å
270	G	75.9	Confident	84.4	Confident	52 Å²	52	62.5 Å²	62.5	54%	0.536	35%	0.348	S	S	.	.	T	Hydrogen-bonded Turn	trans	-47.5	134.2	168.6	0	0	0	0	0	109.9	E268 Y275	E268-G270 VanDerWaalsContact C-N 3.27Å; E268-G270 PolarHBondContact O-N 2.76Å; G270-Y275 VanDerWaalsContact O-CE2 3.27Å; G270-Y275 WeakPolarHBondContact O-CE2 3.1Å
271	N	83.1	Confident	84.5	Confident	87 Å²	87	68.9 Å²	68.9	47%	0.465	38%	0.378	S	S	.	.	T	Hydrogen-bonded Turn	trans	65.8	29.8	-171.9	-53.9	-19.3	0	0	0	115.3	Q50 L269 S273 I274 Y275	Q50-N271 PolarHBondContact OE1-ND2 3.5Å; L269-N271 PolarHBondContact O-N 3.28Å; N271-S273 PolarHBondContact O-N 2.95Å; N271-S273 VanDerWaalsContact O-N 3.09Å; N271-I274 HydrophobicContact CB-CB 4.34Å; N271-I274 HydrophobicContact CB-CD1 4.06Å; N271-I274 HydrophobicContact CB-CG1 4.3Å; N271-I274 WeakPolarHBondContact O-CB 3.37Å; N271-I274 PolarHBondContact O-N 2.96Å; N271-Y275 HydrophobicContact CB-CE2 4.36Å; N271-Y275 WeakPolarHBondContact O-CD2 3.35Å; N271-Y275 PolarHBondContact O-N 3.38Å
272	Y	86.3	Confident	84.5	Confident	78 Å²	78	71.4 Å²	71.4	31%	0.306	38%	0.384	S	S	.	.	H	α-helix	trans	-44.9	-43.4	175.7	-177.9	-90.5	0	0	0	113.5	A266 L269 I274 Y275 F276 L286	A266-Y272 HydrophobicContact CB-CD2 4.45Å; A266-Y272 HydrophobicContact CB-CE2 4.23Å; L269-Y272 HydrophobicContact CB-CD2 4.35Å; L269-Y272 HydrophobicContact CD2-CD2 4.13Å; L269-Y272 WeakPolarHBondContact O-CA 3.34Å; L269-Y272 WeakPolarHBondContact O-CB 3.46Å; L269-Y272 PolarHBondContact O-N 3.37Å; Y272-I274 VanDerWaalsContact C-N 3.27Å; Y272-I274 PolarHBondContact O-N 3.03Å; Y272-Y275 PolarHBondContact O-N 3.22Å; Y272-F276 HydrophobicContact CD1-CB 4.26Å; Y272-F276 HydrophobicContact CE1-CB 3.95Å; Y272-F276 HydrophobicContact CE1-CD2 4Å; Y272-F276 HydrophobicContact CE1-CG 4.19Å; Y272-F276 VanDerWaalsContact O-CB 3.28Å; Y272-F276 WeakPolarHBondContact O-CB 3.39Å; Y272-F276 PolarHBondContact O-N 2.83Å; Y272-L286 HydrophobicContact CD2-CD2 4.11Å; Y272-L286 HydrophobicContact CE2-CD2 3.53Å
273	S	87.8	Confident	84.6	Confident	88 Å²	88	68.6 Å²	68.6	62%	0.615	38%	0.381	S	S	*	.	H	α-helix	trans	-58.3	-36.6	180	53.7	0	0	0	0	113.4	N271 A277	N271-S273 PolarHBondContact O-N 2.95Å; N271-S273 VanDerWaalsContact O-N 3.09Å; S273-A277 WeakPolarHBondContact O-CB 3.48Å; S273-A277 PolarHBondContact O-N 3.41Å
274	I	90.7	Very high	85.1	Confident	57 Å²	57	68.2 Å²	68.2	29%	0.292	37%	0.374	S	S	.	.	H	α-helix	trans	-72.6	-44.8	179.6	-58.8	-176.8	0	0	0	110.1	P49 Q50 N271 Y272 F276 A277 Y278	P49-I274 HydrophobicContact CB-CG2 4.27Å; Q50-I274 VanDerWaalsContact CD-CD1 3.47Å; Q50-I274 HydrophobicContact CG-CG2 4.38Å; N271-I274 HydrophobicContact CB-CB 4.34Å; N271-I274 HydrophobicContact CB-CD1 4.06Å; N271-I274 HydrophobicContact CB-CG1 4.3Å; N271-I274 WeakPolarHBondContact O-CB 3.37Å; N271-I274 PolarHBondContact O-N 2.96Å; Y272-I274 VanDerWaalsContact C-N 3.27Å; Y272-I274 PolarHBondContact O-N 3.03Å; I274-F276 VanDerWaalsContact C-N 3.32Å; I274-F276 PolarHBondContact O-N 3.04Å; I274-A277 PolarHBondContact O-N 3.48Å; I274-Y278 WeakPolarHBondContact O-CB 3.45Å; I274-Y278 PolarHBondContact O-N 2.9Å
275	Y	91.5	Very high	85.9	Confident	13 Å²	13	65 Å²	65	5%	0.051	35%	0.352	C	S	.	.	H	α-helix	trans	-65.7	-37.6	176.1	-60.1	-49.9	0	0	0	112	P49 H78 V82 F86 L269 G270 N271 Y272 Y278 A279	P49-Y275 HydrophobicContact CG-CD1 3.66Å; P49-Y275 HydrophobicContact CG-CE1 3.88Å; H78-Y275 AromaticContact CE1-CE1 3.92Å; V82-Y275 HydrophobicContact CG1-CE2 4.16Å; V82-Y275 WeakPolarHBondContact CG2-OH 3.42Å; F86-Y275 HydrophobicContact CE2-CD1 4.32Å; F86-Y275 AromaticContact CZ-CD1 3.96Å; F86-Y275 HydrophobicContact CZ-CD1 3.96Å; F86-Y275 HydrophobicContact CZ-CG 4.42Å; L269-Y275 HydrophobicContact CD2-CD2 3.5Å; L269-Y275 HydrophobicContact CD2-CE2 4.2Å; L269-Y275 HydrophobicContact CD2-CG 4.24Å; L269-Y275 HydrophobicContact CG-CD2 3.83Å; L269-Y275 HydrophobicContact CG-CE2 4.05Å; G270-Y275 VanDerWaalsContact O-CE2 3.27Å; G270-Y275 WeakPolarHBondContact O-CE2 3.1Å; N271-Y275 HydrophobicContact CB-CE2 4.36Å; N271-Y275 WeakPolarHBondContact O-CD2 3.35Å; N271-Y275 PolarHBondContact O-N 3.38Å; Y272-Y275 PolarHBondContact O-N 3.22Å; Y275-Y278 PolarHBondContact O-N 3.34Å; Y275-A279 VanDerWaalsContact O-CB 3.22Å; Y275-A279 WeakPolarHBondContact O-CB 3.35Å; Y275-A279 PolarHBondContact O-N 3.47Å
276	F	90.9	Very high	86.7	Confident	75 Å²	75	64 Å²	64	33%	0.329	35%	0.346	S	S	.	.	H	α-helix	trans	-65.2	-47.2	176.1	-177	-91.6	0	0	0	111.7	Y272 I274 Y278 A279 Q280 L286	Y272-F276 HydrophobicContact CD1-CB 4.26Å; Y272-F276 HydrophobicContact CE1-CB 3.95Å; Y272-F276 HydrophobicContact CE1-CD2 4Å; Y272-F276 HydrophobicContact CE1-CG 4.19Å; Y272-F276 VanDerWaalsContact O-CB 3.28Å; Y272-F276 WeakPolarHBondContact O-CB 3.39Å; Y272-F276 PolarHBondContact O-N 2.83Å; I274-F276 VanDerWaalsContact C-N 3.32Å; I274-F276 PolarHBondContact O-N 3.04Å; F276-Y278 VanDerWaalsContact C-N 3.34Å; F276-Y278 PolarHBondContact O-N 3.44Å; F276-A279 WeakPolarHBondContact O-CB 3.17Å; F276-A279 PolarHBondContact O-N 3.49Å; F276-Q280 WeakPolarHBondContact O-CB 3.12Å; F276-Q280 PolarHBondContact O-N 3.16Å; F276-L286 HydrophobicContact CB-CD2 4.21Å; F276-L286 HydrophobicContact CD2-CD2 4.42Å
277	A	92.9	Very high	87.5	Confident	55 Å²	55	62.6 Å²	62.6	46%	0.455	33%	0.334	S	S	.	.	H	α-helix	trans	-59.6	-45.2	175.8	0	0	0	0	0	111.5	S273 I274 Q280 E281	S273-A277 WeakPolarHBondContact O-CB 3.48Å; S273-A277 PolarHBondContact O-N 3.41Å; I274-A277 PolarHBondContact O-N 3.48Å; A277-Q280 PolarHBondContact O-N 2.96Å; A277-E281 PolarHBondContact O-N 3.17Å
278	Y	93.7	Very high	88.1	Confident	23 Å²	23	54.9 Å²	54.9	9%	0.09	30%	0.301	C	S	.	.	H	α-helix	trans	-63.4	-43	176.4	-176.6	-97.8	0	0	0	112.5	F46 R47 P49 F86 I274 Y275 F276 Q280 E281 R282 Y284	F46-Y278 AromaticContact CD2-CE1 3.99Å; F46-Y278 HydrophobicContact CD2-CE1 3.99Å; F46-Y278 AromaticContact CE2-CE1 3.85Å; F46-Y278 HydrophobicContact CE2-CE1 3.85Å; R47-Y278 PolarHBondContact N-OH 2.96Å; R47-Y278 PolarHBondContact O-OH 2.87Å; P49-Y278 HydrophobicContact CB-CD2 4.25Å; P49-Y278 HydrophobicContact CB-CG 4.19Å; P49-Y278 HydrophobicContact CG-CD1 3.96Å; P49-Y278 HydrophobicContact CG-CD2 4.32Å; P49-Y278 HydrophobicContact CG-CG 3.85Å; F86-Y278 AromaticContact CE1-CD1 3.86Å; F86-Y278 HydrophobicContact CE1-CD1 3.86Å; F86-Y278 HydrophobicContact CE2-CD1 4.38Å; F86-Y278 AromaticContact CZ-CD1 3.62Å; F86-Y278 HydrophobicContact CZ-CD1 3.62Å; F86-Y278 HydrophobicContact CZ-CE1 4.29Å; I274-Y278 WeakPolarHBondContact O-CB 3.45Å; I274-Y278 PolarHBondContact O-N 2.9Å; Y275-Y278 PolarHBondContact O-N 3.34Å; F276-Y278 VanDerWaalsContact C-N 3.34Å; F276-Y278 PolarHBondContact O-N 3.44Å; Y278-Q280 VanDerWaalsContact C-N 3.3Å; Y278-Q280 PolarHBondContact O-N 3.33Å; Y278-E281 PolarHBondContact O-N 3.18Å; Y278-R282 HydrophobicContact CD1-CG 4.48Å; Y278-R282 HydrophobicContact CD2-CG 4.34Å; Y278-R282 HydrophobicContact CE1-CG 4.05Å; Y278-R282 HydrophobicContact CE2-CG 3.89Å; Y278-R282 WeakPolarHBondContact O-CB 3.5Å; Y278-R282 PolarHBondContact O-N 3.49Å; Y278-Y284 HydrophobicContact CD1-CD2 4.5Å; Y278-Y284 AromaticContact CE1-CD2 3.99Å; Y278-Y284 HydrophobicContact CE1-CD2 3.99Å; Y278-Y284 AromaticContact CE1-CE2 3.95Å; Y278-Y284 HydrophobicContact CE1-CE2 3.95Å
279	A	93	Very high	88.9	Confident	2 Å²	2	49.2 Å²	49.2	2%	0.017	28%	0.275	C	S	.	.	H	α-helix	trans	-59	-43.5	175.5	0	0	0	0	0	111.3	F86 Y275 F276 R282 G283 Y284 L286	F86-A279 HydrophobicContact CD1-CB 4.23Å; F86-A279 HydrophobicContact CE1-CB 3.94Å; Y275-A279 VanDerWaalsContact O-CB 3.22Å; Y275-A279 WeakPolarHBondContact O-CB 3.35Å; Y275-A279 PolarHBondContact O-N 3.47Å; F276-A279 WeakPolarHBondContact O-CB 3.17Å; F276-A279 PolarHBondContact O-N 3.49Å; A279-R282 PolarHBondContact O-N 3.47Å; A279-G283 CarbonylContact O-C 3.54Å; A279-G283 WeakPolarHBondContact O-CA 3.33Å; A279-G283 PolarHBondContact O-N 2.89Å; A279-Y284 WeakPolarHBondContact CB-O 3.36Å; A279-Y284 PolarHBondContact O-N 2.86Å; A279-L286 HydrophobicContact CB-CB 4.22Å
280	Q	92.9	Very high	89.2	Confident	134 Å²	134	51.8 Å²	51.8	63%	0.626	29%	0.288	S	S	*	.	H	α-helix	trans	-67.4	-43.2	178.9	-172.4	175.5	-2.4	0	0	112.1	F276 A277 Y278 R282	F276-Q280 WeakPolarHBondContact O-CB 3.12Å; F276-Q280 PolarHBondContact O-N 3.16Å; A277-Q280 PolarHBondContact O-N 2.96Å; Y278-Q280 VanDerWaalsContact C-N 3.3Å; Y278-Q280 PolarHBondContact O-N 3.33Å; Q280-R282 VanDerWaalsContact C-N 3.33Å; Q280-R282 PolarHBondContact O-N 3.04Å
281	E	93.8	Very high	89.7	Confident	137 Å²	137	56.7 Å²	56.7	64%	0.64	30%	0.303	S	S	*	.	H	α-helix	trans	-59.8	-43.9	176.1	-174.1	-161.7	131.9	0	0	111.5	A277 Y278	A277-E281 PolarHBondContact O-N 3.17Å; Y278-E281 PolarHBondContact O-N 3.18Å
282	R	92.4	Very high	90	Very high	75 Å²	75	58.4 Å²	58.4	28%	0.283	30%	0.302	S	S	.	.	H	α-helix	trans	-92	-4.2	-174.5	-63.6	-65.2	177.2	142	-4.3	114.8	Y278 A279 Q280 Y284	Y278-R282 HydrophobicContact CD1-CG 4.48Å; Y278-R282 HydrophobicContact CD2-CG 4.34Å; Y278-R282 HydrophobicContact CE1-CG 4.05Å; Y278-R282 HydrophobicContact CE2-CG 3.89Å; Y278-R282 WeakPolarHBondContact O-CB 3.5Å; Y278-R282 PolarHBondContact O-N 3.49Å; A279-R282 PolarHBondContact O-N 3.47Å; Q280-R282 VanDerWaalsContact C-N 3.33Å; Q280-R282 PolarHBondContact O-N 3.04Å; R282-Y284 VanDerWaalsContact C-N 3.26Å; R282-Y284 HydrophobicContact CB-CD2 3.49Å; R282-Y284 VanDerWaalsContact CB-CD2 3.49Å; R282-Y284 HydrophobicContact CB-CE2 3.43Å; R282-Y284 VanDerWaalsContact CB-CE2 3.43Å; R282-Y284 HydrophobicContact CB-CG 4.08Å; R282-Y284 HydrophobicContact CG-CD2 4.31Å; R282-Y284 HydrophobicContact CG-CE2 3.97Å; R282-Y284 PolarHBondContact O-N 3.35Å
283	G	92.3	Very high	90.3	Very high	48 Å²	48	54.7 Å²	54.7	50%	0.495	29%	0.288	S	S	.	.	T	Hydrogen-bonded Turn	trans	66.5	25.8	-175	0	0	0	0	0	113.9	A279	A279-G283 CarbonylContact O-C 3.54Å; A279-G283 WeakPolarHBondContact O-CA 3.33Å; A279-G283 PolarHBondContact O-N 2.89Å
284	Y	93.9	Very high	90.3	Very high	28 Å²	28	54.5 Å²	54.5	11%	0.11	28%	0.28	C	S	.	.	P	Polyproline II helix	trans	-84.7	146.7	174.6	-61.4	-37.9	0	0	0	111.1	F46 N88 Y278 A279 R282 Y311	F46-Y284 HydrophobicContact CD2-CD2 4.28Å; F46-Y284 AromaticContact CD2-CE2 3.71Å; F46-Y284 HydrophobicContact CD2-CE2 3.71Å; N88-Y284 WeakPolarHBondContact ND2-CE1 3.23Å; Y278-Y284 HydrophobicContact CD1-CD2 4.5Å; Y278-Y284 AromaticContact CE1-CD2 3.99Å; Y278-Y284 HydrophobicContact CE1-CD2 3.99Å; Y278-Y284 AromaticContact CE1-CE2 3.95Å; Y278-Y284 HydrophobicContact CE1-CE2 3.95Å; A279-Y284 WeakPolarHBondContact CB-O 3.36Å; A279-Y284 PolarHBondContact O-N 2.86Å; R282-Y284 VanDerWaalsContact C-N 3.26Å; R282-Y284 HydrophobicContact CB-CD2 3.49Å; R282-Y284 VanDerWaalsContact CB-CD2 3.49Å; R282-Y284 HydrophobicContact CB-CE2 3.43Å; R282-Y284 VanDerWaalsContact CB-CE2 3.43Å; R282-Y284 HydrophobicContact CB-CG 4.08Å; R282-Y284 HydrophobicContact CG-CD2 4.31Å; R282-Y284 HydrophobicContact CG-CE2 3.97Å; R282-Y284 PolarHBondContact O-N 3.35Å; Y284-Y311 HydrophobicContact CD1-CD1 4.02Å; Y284-Y311 AromaticContact CD1-CE1 3.6Å; Y284-Y311 HydrophobicContact CD1-CE1 3.6Å; Y284-Y311 HydrophobicContact CE1-CD1 4.12Å; Y284-Y311 HydrophobicContact CE1-CE1 4.18Å
285	N	93.2	Very high	90.5	Very high	2 Å²	2	51.9 Å²	51.9	1%	0.011	27%	0.266	C	S	.	.	P	Polyproline II helix	trans	-82.5	128.7	169	-68.1	-23.6	0	0	0	109.4	F86 E87 R292 L293 R310 Y311	F86-N285 WeakPolarHBondContact CA-O 3.25Å; E87-N285 HydrophobicContact CB-CB 3.84Å; E87-N285 PolarHBondContact N-O 3.26Å; E87-N285 WeakPolarHBondContact OE2-CB 3.49Å; E87-N285 PolarHBondContact OE2-ND2 2.98Å; N285-R292 PolarHBondContact ND2-O 3.1Å; N285-R292 WeakPolarHBondContact OD1-CB 3.32Å; N285-R292 WeakPolarHBondContact OD1-CD 3.46Å; N285-L293 HydrophobicContact CB-CD2 3.96Å; N285-R310 PolarHBondContact ND2-NH2 3.4Å; N285-R310 PolarHBondContact OD1-NH2 2.97Å; N285-Y311 PolarHBondContact N-OH 2.84Å
286	L	90.7	Very high	90.5	Very high	0 Å²	0	52 Å²	52	0%	0	27%	0.269	C	S	.	.	B	Isolated β-bridge	trans	-90.9	157.3	173.1	-165.8	66.6	0	0	0	109.8	F86 L269 Y272 F276 A279 Q289	F86-L286 HydrophobicContact CD1-CD1 3.79Å; F86-L286 HydrophobicContact CE1-CD1 3.78Å; F86-L286 HydrophobicContact CZ-CD1 4.47Å; L269-L286 HydrophobicContact CD2-CD1 4.47Å; Y272-L286 HydrophobicContact CD2-CD2 4.11Å; Y272-L286 HydrophobicContact CE2-CD2 3.53Å; F276-L286 HydrophobicContact CB-CD2 4.21Å; F276-L286 HydrophobicContact CD2-CD2 4.42Å; A279-L286 HydrophobicContact CB-CB 4.22Å; L286-Q289 HydrophobicContact CB-CG 4.47Å; L286-Q289 WeakPolarHBondContact O-CB 3.33Å; L286-Q289 PolarHBondContact O-N 3.17Å
287	L	88.4	Confident	90.5	Very high	1 Å²	1	54.4 Å²	54.4	1%	0.005	28%	0.281	C	S	.	.	T	Hydrogen-bonded Turn	trans	-40.1	143.4	163.3	-163.4	86.2	0	0	0	110.5	T85 R259 F260 Q289	T85-L287 PolarHBondContact O-N 3.17Å; R259-L287 HydrophobicContact CG-CD1 3.93Å; R259-L287 WeakPolarHBondContact O-CD1 3.05Å; F260-L287 HydrophobicContact CD1-CD1 4.15Å; F260-L287 HydrophobicContact CD2-CD1 4.46Å; F260-L287 HydrophobicContact CE1-CD1 4.23Å; F260-L287 HydrophobicContact CG-CD1 4.26Å; F260-L287 HydrophobicContact CZ-CD1 4.43Å; L287-Q289 VanDerWaalsContact C-N 3.25Å; L287-Q289 PolarHBondContact O-N 3.29Å
288	C	80.6	Confident	90.5	Very high	36 Å²	36	57.8 Å²	57.8	24%	0.243	28%	0.283	C	S	.	.	T	Hydrogen-bonded Turn	trans	74.2	-2.6	176.7	-50.9	0	0	0	0	117	C264 L290	C264-C288 VanDerWaalsContact CA-SG 3.52Å; C264-C288 HydrophobicContact CB-CB 3.88Å; C264-C288 WeakPolarHBondContact CB-SG 3.49Å; C264-C288 WeakPolarHBondContact SG-CB 3.31Å; C264-C288 CovalentContact SG-SG 1.98Å; C264-C288 PolarHBondContact SG-SG 3.45Å; C288-L290 PolarHBondContact O-N 3.06Å; C288-L290 VanDerWaalsContact O-N 3.09Å
289	Q	86.1	Confident	90.3	Very high	30 Å²	30	65 Å²	65	14%	0.14	32%	0.322	C	S	.	.			trans	-86.9	62.4	174.8	-62.8	-175.2	-36.2	0	0	110.6	L286 L287 D291 R292 L293	L286-Q289 HydrophobicContact CB-CG 4.47Å; L286-Q289 WeakPolarHBondContact O-CB 3.33Å; L286-Q289 PolarHBondContact O-N 3.17Å; L287-Q289 VanDerWaalsContact C-N 3.25Å; L287-Q289 PolarHBondContact O-N 3.29Å; Q289-D291 PolarHBondContact O-N 2.93Å; Q289-D291 VanDerWaalsContact O-N 3.17Å; Q289-R292 HydrophobicContact CB-CB 4.31Å; Q289-R292 HydrophobicContact CB-CG 4.4Å; Q289-R292 PolarHBondContact O-N 3.01Å; Q289-L293 WeakPolarHBondContact O-CG 3.36Å; Q289-L293 PolarHBondContact O-N 3.24Å
290	L	84.2	Confident	90.1	Very high	66 Å²	66	71 Å²	71	35%	0.346	35%	0.352	S	S	.	.	G	3₁₀ helix	trans	-53.8	-40.5	-171.6	-157.6	77.6	0	0	0	112.3	C261 C288 R292 L293 C296	C261-L290 HydrophobicContact CB-CD1 4.23Å; C288-L290 PolarHBondContact O-N 3.06Å; C288-L290 VanDerWaalsContact O-N 3.09Å; L290-R292 PolarHBondContact O-N 3.03Å; L290-L293 PolarHBondContact O-N 3.26Å; L290-C296 HydrophobicContact CD1-CB 4.1Å
291	D	86.1	Confident	89.9	Confident	156 Å²	156	66.3 Å²	66.3	83%	0.834	33%	0.333	S	S	*	.	G	3₁₀ helix	trans	-60.2	-18.1	178.2	-53.8	-29.8	0	0	0	114.1	Q289	Q289-D291 PolarHBondContact O-N 2.93Å; Q289-D291 VanDerWaalsContact O-N 3.17Å
292	R	89.1	Confident	89.7	Confident	123 Å²	123	63.3 Å²	63.3	46%	0.464	32%	0.319	S	S	.	.	G	3₁₀ helix	trans	-101.5	-5.8	177.8	-61	-173	168.7	-172.7	-3.9	113.4	N285 Q289 L290	N285-R292 PolarHBondContact ND2-O 3.1Å; N285-R292 WeakPolarHBondContact OD1-CB 3.32Å; N285-R292 WeakPolarHBondContact OD1-CD 3.46Å; Q289-R292 HydrophobicContact CB-CB 4.31Å; Q289-R292 HydrophobicContact CB-CG 4.4Å; Q289-R292 PolarHBondContact O-N 3.01Å; L290-R292 PolarHBondContact O-N 3.03Å
293	L	91.2	Very high	89.8	Confident	0 Å²	0	59.8 Å²	59.8	0%	0	31%	0.305	C	S	.	.			trans	-104.7	72.8	-174.2	-63.3	172.3	0	0	0	110.5	E87 F260 N285 Q289 L290 W295 C296	E87-L293 HydrophobicContact CB-CD2 4.06Å; E87-L293 VanDerWaalsContact CD-CD2 3.47Å; E87-L293 HydrophobicContact CG-CD2 3.86Å; E87-L293 WeakPolarHBondContact OE1-CD2 3.23Å; F260-L293 HydrophobicContact CB-CD1 4.13Å; F260-L293 HydrophobicContact CD1-CD1 4.05Å; F260-L293 HydrophobicContact CD1-CD2 4.46Å; N285-L293 HydrophobicContact CB-CD2 3.96Å; Q289-L293 WeakPolarHBondContact O-CG 3.36Å; Q289-L293 PolarHBondContact O-N 3.24Å; L290-L293 PolarHBondContact O-N 3.26Å; L293-W295 PolarHBondContact O-N 2.91Å; L293-C296 HydrophobicContact CB-CB 4.5Å; L293-C296 WeakPolarHBondContact O-CB 3.08Å; L293-C296 PolarHBondContact O-N 3.12Å
294	D	89.7	Confident	89.8	Confident	84 Å²	84	58.7 Å²	58.7	45%	0.449	29%	0.286	S	S	.	.	G	3₁₀ helix	trans	-50.1	-37.6	-174	-54.8	-36.5	0	0	0	113.6	C296 H297 Y298	D294-C296 PolarHBondContact O-N 3.41Å; D294-H297 PolarHBondContact O-N 3.34Å; D294-Y298 HydrophobicContact CB-CE1 4.35Å
295	W	93.1	Very high	89.6	Confident	2 Å²	2	60.6 Å²	60.6	1%	0.008	30%	0.303	C	S	.	.	G	3₁₀ helix	trans	-69.9	-16	-177	60.7	-92.8	0	0	0	114.2	E87 I256 Y257 F260 C261 L293 H297 Y298 P301 A306	E87-W295 VanDerWaalsContact OE1-CD1 3.26Å; E87-W295 PolarHBondContact OE1-NE1 2.88Å; I256-W295 HydrophobicContact CG2-CH2 3.77Å; I256-W295 HydrophobicContact CG2-CZ2 4.3Å; I256-W295 HydrophobicContact CG2-CZ3 4.49Å; Y257-W295 HydrophobicContact CD2-CZ3 4.12Å; F260-W295 HydrophobicContact CB-CH2 3.72Å; F260-W295 HydrophobicContact CB-CZ2 3.83Å; F260-W295 HydrophobicContact CG-CH2 4.4Å; F260-W295 HydrophobicContact CG-CZ2 4.22Å; C261-W295 VanDerWaalsContact SG-CH2 3.51Å; C261-W295 WeakPolarHBondContact SG-CZ3 3.07Å; L293-W295 PolarHBondContact O-N 2.91Å; W295-H297 PolarHBondContact O-N 3.23Å; W295-Y298 VanDerWaalsContact CA-CD2 3.5Å; W295-Y298 HydrophobicContact CB-CD2 3.87Å; W295-Y298 HydrophobicContact CB-CE2 3.81Å; W295-P301 HydrophobicContact CE3-CB 4.42Å; W295-P301 WeakPolarHBondContact O-CA 3.25Å; W295-P301 WeakPolarHBondContact O-CB 3.37Å; W295-A306 HydrophobicContact CB-CB 3.62Å; W295-A306 HydrophobicContact CG-CB 4.03Å
296	C	92.8	Very high	89.6	Confident	14 Å²	14	61.5 Å²	61.5	10%	0.095	31%	0.312	C	S	.	.	G	3₁₀ helix	trans	-66.4	-23.5	169.9	-67.3	0	0	0	0	112.1	C261 L290 L293 D294	C261-C296 HydrophobicContact CB-CB 3.72Å; C261-C296 WeakPolarHBondContact CB-SG 3.39Å; C261-C296 VanDerWaalsContact SG-CA 3.53Å; C261-C296 WeakPolarHBondContact SG-CB 3.26Å; C261-C296 CovalentContact SG-SG 2.03Å; C261-C296 PolarHBondContact SG-SG 3.13Å; L290-C296 HydrophobicContact CD1-CB 4.1Å; L293-C296 HydrophobicContact CB-CB 4.5Å; L293-C296 WeakPolarHBondContact O-CB 3.08Å; L293-C296 PolarHBondContact O-N 3.12Å; D294-C296 PolarHBondContact O-N 3.41Å
297	H	91.3	Very high	89.7	Confident	127 Å²	127	61.5 Å²	61.5	59%	0.588	31%	0.312	S	S	*	.	G	3₁₀ helix	trans	-100.3	-0.9	-176.1	-58.1	-65.4	0	0	0	113.9	D294 W295	D294-H297 PolarHBondContact O-N 3.34Å; W295-H297 PolarHBondContact O-N 3.23Å
298	Y	91.6	Very high	89.8	Confident	125 Å²	125	63.4 Å²	63.4	49%	0.49	32%	0.32	S	S	.	.	S	Bend	trans	-74.1	150.8	175.3	-62	-20	0	0	0	111.5	D294 W295 I300 A306	D294-Y298 HydrophobicContact CB-CE1 4.35Å; W295-Y298 VanDerWaalsContact CA-CD2 3.5Å; W295-Y298 HydrophobicContact CB-CD2 3.87Å; W295-Y298 HydrophobicContact CB-CE2 3.81Å; Y298-I300 WeakPolarHBondContact CB-O 3.4Å; Y298-I300 PolarHBondContact O-N 3.23Å; Y298-A306 HydrophobicContact CE2-CB 4.34Å
299	L	89.8	Confident	90.3	Very high	176 Å²	176	68.7 Å²	68.7	92%	0.921	34%	0.339	S	S	*	.	S	Bend	trans	-52.9	-40.3	176.2	-179.5	67.8	0	0	0	112
300	I	89.4	Confident	90.5	Very high	127 Å²	127	72.7 Å²	72.7	65%	0.651	35%	0.353	S	S	*	.	S	Bend	trans	-116.5	108.7	168.8	-56.9	177.9	0	0	0	105.8	Y298 F302	Y298-I300 WeakPolarHBondContact CB-O 3.4Å; Y298-I300 PolarHBondContact O-N 3.23Å; I300-F302 HydrophobicContact CG2-CB 4.48Å; I300-F302 PolarHBondContact O-N 3.44Å
301	P	88.5	Confident	90.8	Very high	35 Å²	35	72 Å²	72	23%	0.227	35%	0.346	C	S	.	.			trans	-78.2	66.7	-172.3	31.8	-36.5	0	0	0	111.5	Y257 W295 S303	Y257-P301 HydrophobicContact CD1-CG 4.43Å; Y257-P301 HydrophobicContact CD2-CB 3.44Å; Y257-P301 VanDerWaalsContact CD2-CB 3.44Å; Y257-P301 HydrophobicContact CD2-CG 3.47Å; Y257-P301 VanDerWaalsContact CD2-CG 3.47Å; Y257-P301 HydrophobicContact CE1-CG 4.42Å; Y257-P301 HydrophobicContact CE2-CB 3.5Å; Y257-P301 VanDerWaalsContact CE2-CB 3.5Å; Y257-P301 HydrophobicContact CE2-CG 3.47Å; Y257-P301 VanDerWaalsContact CE2-CG 3.47Å; Y257-P301 HydrophobicContact CG-CB 4.35Å; Y257-P301 HydrophobicContact CG-CG 3.98Å; W295-P301 HydrophobicContact CE3-CB 4.42Å; W295-P301 WeakPolarHBondContact O-CA 3.25Å; W295-P301 WeakPolarHBondContact O-CB 3.37Å; P301-S303 PolarHBondContact O-N 3.38Å
302	F	90.5	Very high	90.9	Very high	75 Å²	75	68.3 Å²	68.3	33%	0.329	32%	0.321	S	S	.	.			trans	-85.1	96	-173.9	-165	-115.2	0	0	0	111.1	F249 Q253 I300 S305	F249-F302 AromaticContact CE1-CE2 3.55Å; F249-F302 HydrophobicContact CE1-CE2 3.55Å; F249-F302 AromaticContact CE1-CZ 3.78Å; F249-F302 HydrophobicContact CE1-CZ 3.78Å; F249-F302 AromaticContact CZ-CE2 3.58Å; F249-F302 HydrophobicContact CZ-CE2 3.58Å; F249-F302 AromaticContact CZ-CZ 3.45Å; F249-F302 HydrophobicContact CZ-CZ 3.45Å; F249-F302 VanDerWaalsContact CZ-CZ 3.45Å; Q253-F302 HydrophobicContact CG-CD2 4.34Å; Q253-F302 HydrophobicContact CG-CE2 4.02Å; I300-F302 HydrophobicContact CG2-CB 4.48Å; I300-F302 PolarHBondContact O-N 3.44Å; F302-S305 VanDerWaalsContact CE1-OG 3.27Å; F302-S305 WeakPolarHBondContact CE1-OG 3.31Å
303	S	93.4	Very high	90.7	Very high	0 Å²	0	67 Å²	67	0%	0	32%	0.323	C	S	.	.	H	α-helix	trans	-66	-41.1	-173	67.2	0	0	0	0	112.5	Q253 I256 P301 S305 A306 I307	Q253-S303 PolarHBondContact OE1-OG 3.27Å; Q253-S303 VanDerWaalsContact OE1-OG 3.1Å; I256-S303 WeakPolarHBondContact CG2-OG 3.19Å; P301-S303 PolarHBondContact O-N 3.38Å; S303-S305 PolarHBondContact O-N 2.96Å; S303-A306 PolarHBondContact O-N 2.91Å; S303-I307 WeakPolarHBondContact O-CB 3.03Å; S303-I307 WeakPolarHBondContact O-CD1 3.13Å; S303-I307 WeakPolarHBondContact O-CG1 3.28Å; S303-I307 PolarHBondContact O-N 3.38Å
304	Y	92.1	Very high	90.3	Very high	26 Å²	26	67.8 Å²	67.8	10%	0.102	33%	0.328	C	S	.	.	H	α-helix	trans	-56.8	-52.6	-169.5	-170.2	-102.3	0	0	0	113.2	F93 S196 A306 Q308	F93-Y304 AromaticContact CE2-CD2 3.97Å; F93-Y304 HydrophobicContact CE2-CD2 3.97Å; F93-Y304 AromaticContact CE2-CE2 3.77Å; F93-Y304 HydrophobicContact CE2-CE2 3.77Å; S196-Y304 PolarHBondContact OG-OH 3.47Å; Y304-A306 PolarHBondContact O-N 2.94Å; Y304-Q308 HydrophobicContact CD1-CG 4.41Å; Y304-Q308 VanDerWaalsContact CE1-CD 3.4Å; Y304-Q308 HydrophobicContact CE1-CG 4.16Å; Y304-Q308 HydrophobicContact CE2-CG 4.5Å; Y304-Q308 VanDerWaalsContact O-CB 3.23Å; Y304-Q308 WeakPolarHBondContact O-CB 3.31Å; Y304-Q308 VanDerWaalsContact O-CG 3.31Å; Y304-Q308 WeakPolarHBondContact O-CG 3.22Å; Y304-Q308 PolarHBondContact O-N 3.16Å; Y304-Q308 PolarHBondContact OH-NE2 3.33Å
305	S	90.1	Very high	89.8	Confident	67 Å²	67	65.3 Å²	65.3	47%	0.469	32%	0.322	S	S	.	.	H	α-helix	trans	-67.6	-36.1	-180	-65.8	0	0	0	0	113	F302 S303 K309	F302-S305 VanDerWaalsContact CE1-OG 3.27Å; F302-S305 WeakPolarHBondContact CE1-OG 3.31Å; S303-S305 PolarHBondContact O-N 2.96Å; S305-K309 WeakPolarHBondContact O-CB 3.38Å; S305-K309 PolarHBondContact O-N 3.24Å
306	A	92.2	Very high	89.5	Confident	22 Å²	22	71.7 Å²	71.7	18%	0.182	36%	0.355	C	S	.	.	H	α-helix	trans	-66	-46.2	178.6	0	0	0	0	0	111.4	W295 Y298 S303 Y304 K309 R310	W295-A306 HydrophobicContact CB-CB 3.62Å; W295-A306 HydrophobicContact CG-CB 4.03Å; Y298-A306 HydrophobicContact CE2-CB 4.34Å; S303-A306 PolarHBondContact O-N 2.91Å; Y304-A306 PolarHBondContact O-N 2.94Å; A306-K309 PolarHBondContact O-N 3.1Å; A306-R310 WeakPolarHBondContact O-CB 3.35Å; A306-R310 PolarHBondContact O-N 2.93Å
307	I	93.6	Very high	88.9	Confident	0 Å²	0	76.1 Å²	76.1	0%	0	38%	0.378	C	S	.	.	H	α-helix	trans	-64.2	-46.8	178.6	-70.1	169	0	0	0	110.7	E87 A90 A91 S303 K309 R310 Y311 W312	E87-I307 HydrophobicContact CG-CD1 3.97Å; E87-I307 HydrophobicContact CG-CG1 3.76Å; E87-I307 WeakPolarHBondContact O-CD1 3.37Å; A90-I307 HydrophobicContact CB-CD1 3.72Å; A91-I307 HydrophobicContact CB-CG2 4.06Å; S303-I307 WeakPolarHBondContact O-CB 3.03Å; S303-I307 WeakPolarHBondContact O-CD1 3.13Å; S303-I307 WeakPolarHBondContact O-CG1 3.28Å; S303-I307 PolarHBondContact O-N 3.38Å; I307-K309 VanDerWaalsContact C-N 3.32Å; I307-K309 PolarHBondContact O-N 2.99Å; I307-R310 PolarHBondContact O-N 2.8Å; I307-Y311 HydrophobicContact CG2-CD2 3.98Å; I307-Y311 HydrophobicContact CG2-CE2 4.42Å; I307-Y311 WeakPolarHBondContact O-CD2 3.19Å; I307-Y311 PolarHBondContact O-N 3.35Å; I307-W312 HydrophobicContact CG2-CZ3 3.83Å
308	Q	91	Very high	88.1	Confident	41 Å²	41	71.6 Å²	71.6	19%	0.192	37%	0.365	C	S	.	.	H	α-helix	trans	-56.4	-47.6	175.8	-83.8	-152	-36.6	0	0	111.3	Y304 R310 W312 N313 V314	Y304-Q308 HydrophobicContact CD1-CG 4.41Å; Y304-Q308 VanDerWaalsContact CE1-CD 3.4Å; Y304-Q308 HydrophobicContact CE1-CG 4.16Å; Y304-Q308 HydrophobicContact CE2-CG 4.5Å; Y304-Q308 VanDerWaalsContact O-CB 3.23Å; Y304-Q308 WeakPolarHBondContact O-CB 3.31Å; Y304-Q308 VanDerWaalsContact O-CG 3.31Å; Y304-Q308 WeakPolarHBondContact O-CG 3.22Å; Y304-Q308 PolarHBondContact O-N 3.16Å; Y304-Q308 PolarHBondContact OH-NE2 3.33Å; Q308-R310 PolarHBondContact O-N 3.24Å; Q308-W312 PolarHBondContact O-N 3.02Å; Q308-N313 PolarHBondContact O-N 3.44Å; Q308-V314 HydrophobicContact CB-CG2 3.49Å; Q308-V314 VanDerWaalsContact CB-CG2 3.49Å; Q308-V314 HydrophobicContact CG-CG2 4.32Å; Q308-V314 WeakPolarHBondContact O-CG2 3.29Å
309	K	90.1	Very high	87.5	Confident	147 Å²	147	66.3 Å²	66.3	64%	0.639	35%	0.345	S	S	*	.	H	α-helix	trans	-61.1	-44.4	176.6	-174.5	179.6	177.8	-175.4	0	112.5	S305 A306 I307 N313 V314	S305-K309 WeakPolarHBondContact O-CB 3.38Å; S305-K309 PolarHBondContact O-N 3.24Å; A306-K309 PolarHBondContact O-N 3.1Å; I307-K309 VanDerWaalsContact C-N 3.32Å; I307-K309 PolarHBondContact O-N 2.99Å; K309-N313 VanDerWaalsContact O-CA 3.23Å; K309-N313 WeakPolarHBondContact O-CA 3.36Å; K309-N313 PolarHBondContact O-N 3.26Å; K309-V314 WeakPolarHBondContact CA-O 3.33Å
310	R	91.2	Very high	87.2	Confident	114 Å²	114	63.4 Å²	63.4	43%	0.43	32%	0.322	S	S	.	.	H	α-helix	trans	-67.5	-49.9	-175.7	-177.4	173.2	-178.6	123.4	-3.5	113.2	E87 N285 A306 I307 Q308	E87-R310 IonicContact OE2-NE 3.7Å; N285-R310 PolarHBondContact ND2-NH2 3.4Å; N285-R310 PolarHBondContact OD1-NH2 2.97Å; A306-R310 WeakPolarHBondContact O-CB 3.35Å; A306-R310 PolarHBondContact O-N 2.93Å; I307-R310 PolarHBondContact O-N 2.8Å; Q308-R310 PolarHBondContact O-N 3.24Å
311	Y	90.7	Very high	87	Confident	51 Å²	51	62.1 Å²	62.1	20%	0.2	31%	0.314	C	S	.	.	H	α-helix	trans	-97.1	-22.3	-169.6	-63.3	-74.4	0	0	0	114.1	E87 N88 Y284 N285 I307	E87-Y311 HydrophobicContact CB-CE2 4.29Å; E87-Y311 HydrophobicContact CG-CE2 4.01Å; E87-Y311 VanDerWaalsContact OE2-CE2 3.26Å; E87-Y311 WeakPolarHBondContact OE2-CE2 3.46Å; E87-Y311 VanDerWaalsContact OE2-CZ 3.31Å; E87-Y311 PolarHBondContact OE2-OH 3.45Å; N88-Y311 HydrophobicContact CB-CD1 4.19Å; N88-Y311 HydrophobicContact CB-CD2 3.79Å; N88-Y311 HydrophobicContact CB-CE1 4.33Å; N88-Y311 HydrophobicContact CB-CE2 3.92Å; N88-Y311 HydrophobicContact CB-CG 3.91Å; Y284-Y311 HydrophobicContact CD1-CD1 4.02Å; Y284-Y311 AromaticContact CD1-CE1 3.6Å; Y284-Y311 HydrophobicContact CD1-CE1 3.6Å; Y284-Y311 HydrophobicContact CE1-CD1 4.12Å; Y284-Y311 HydrophobicContact CE1-CE1 4.18Å; N285-Y311 PolarHBondContact N-OH 2.84Å; I307-Y311 HydrophobicContact CG2-CD2 3.98Å; I307-Y311 HydrophobicContact CG2-CE2 4.42Å; I307-Y311 WeakPolarHBondContact O-CD2 3.19Å; I307-Y311 PolarHBondContact O-N 3.35Å
312	W	87.9	Confident	86.8	Confident	79 Å²	79	71.5 Å²	71.5	30%	0.299	35%	0.345	S	S	.	.	H	α-helix	trans	-117.4	2.2	-179.7	-67.4	-88.3	0	0	0	113.6	N88 A91 F92 I307 Q308 V314 N376	N88-W312 HydrophobicContact CB-CH2 4.28Å; A91-W312 HydrophobicContact CB-CH2 3.67Å; A91-W312 HydrophobicContact CB-CZ3 3.75Å; F92-W312 HydrophobicContact CE2-CH2 4Å; F92-W312 HydrophobicContact CE2-CZ2 4.03Å; F92-W312 HydrophobicContact CZ-CH2 4.42Å; F92-W312 HydrophobicContact CZ-CZ2 4.04Å; I307-W312 HydrophobicContact CG2-CZ3 3.83Å; Q308-W312 PolarHBondContact O-N 3.02Å; W312-V314 HydrophobicContact CB-CG1 4.47Å; W312-V314 HydrophobicContact CB-CG2 4.08Å; W312-V314 PolarHBondContact O-N 3.29Å; W312-V314 VanDerWaalsContact O-N 3.12Å; W312-N376 PolarHBondContact O-OD1 2.94Å
313	N	84.5	Confident	86.6	Confident	95 Å²	95	76.8 Å²	76.8	51%	0.508	37%	0.367	S	S	.	.			trans	50.4	34	-178.7	-166.1	38.8	0	0	0	113.2	Q308 K309	Q308-N313 PolarHBondContact O-N 3.44Å; K309-N313 VanDerWaalsContact O-CA 3.23Å; K309-N313 WeakPolarHBondContact O-CA 3.36Å; K309-N313 PolarHBondContact O-N 3.26Å
314	V	82.7	Confident	86.3	Confident	17 Å²	17	80.1 Å²	80.1	10%	0.103	38%	0.382	C	S	.	.			trans	-85.4	135.1	177.6	-81.4	0	0	0	0	110.2	Q308 K309 W312 C374 N376	Q308-V314 HydrophobicContact CB-CG2 3.49Å; Q308-V314 VanDerWaalsContact CB-CG2 3.49Å; Q308-V314 HydrophobicContact CG-CG2 4.32Å; Q308-V314 WeakPolarHBondContact O-CG2 3.29Å; K309-V314 WeakPolarHBondContact CA-O 3.33Å; W312-V314 HydrophobicContact CB-CG1 4.47Å; W312-V314 HydrophobicContact CB-CG2 4.08Å; W312-V314 PolarHBondContact O-N 3.29Å; W312-V314 VanDerWaalsContact O-N 3.12Å; V314-C374 WeakPolarHBondContact CB-O 3.48Å; V314-N376 WeakPolarHBondContact CG1-OD1 3.08Å
315	G	80.3	Confident	86.3	Confident	32 Å²	32	83 Å²	83	33%	0.33	40%	0.399	S	S	.	.	S	Bend	trans	-178.6	170.6	-175.8	0	0	0	0	0	109.4	L317 G318	G315-L317 PolarHBondContact O-N 2.9Å; G315-G318 PolarHBondContact O-N 3.12Å
316	L	85.4	Confident	86.3	Confident	135 Å²	135	83.9 Å²	83.9	71%	0.707	40%	0.403	S	S	*	.	T	Hydrogen-bonded Turn	trans	-59.9	110.9	-178.3	-172.7	67.4	0	0	0	110.3	G318 A373	L316-G318 PolarHBondContact O-N 3.32Å; L316-G318 VanDerWaalsContact O-N 3.08Å; L316-A373 CarbonylContact C-O 3.48Å; L316-A373 WeakPolarHBondContact CA-O 3.49Å; L316-A373 HydrophobicContact CD1-CB 4.17Å
317	L	80.9	Confident	86.2	Confident	108 Å²	108	84 Å²	84	57%	0.565	40%	0.402	S	S	*	.	T	Hydrogen-bonded Turn	trans	57.6	14.5	-178.1	-54.5	175.4	0	0	0	115.3	G315 Y319 Y320 A373	G315-L317 PolarHBondContact O-N 2.9Å; L317-Y319 PolarHBondContact O-N 3Å; L317-Y320 HydrophobicContact CB-CD2 4.26Å; L317-Y320 HydrophobicContact CB-CE2 4.47Å; L317-Y320 HydrophobicContact CD2-CD2 4.18Å; L317-Y320 HydrophobicContact CD2-CE2 3.6Å; L317-A373 PolarHBondContact N-O 3.37Å
318	G	74.1	Confident	86.2	Confident	32 Å²	32	86 Å²	86	33%	0.33	41%	0.411	S	S	.	.	T	Hydrogen-bonded Turn	trans	-69.6	-15.8	-178	0	0	0	0	0	114.7	G315 L316	G315-G318 PolarHBondContact O-N 3.12Å; L316-G318 PolarHBondContact O-N 3.32Å; L316-G318 VanDerWaalsContact O-N 3.08Å
319	Y	78.7	Confident	86.3	Confident	14 Å²	14	89 Å²	89	6%	0.055	43%	0.428	C	S	.	.	T	Hydrogen-bonded Turn	trans	-85.6	-15.6	-173.6	-172.1	-104.7	0	0	0	114.6	L317 Q321 K324 C327 F328 N376 V377 E378	L317-Y319 PolarHBondContact O-N 3Å; Y319-Q321 PolarHBondContact O-N 3.17Å; Y319-K324 HydrophobicContact CD2-CG 4.43Å; Y319-K324 HydrophobicContact CE1-CB 3.97Å; Y319-K324 HydrophobicContact CE1-CG 4.3Å; Y319-K324 HydrophobicContact CE2-CB 4.49Å; Y319-K324 HydrophobicContact CE2-CD 3.84Å; Y319-K324 HydrophobicContact CE2-CG 3.96Å; Y319-C327 WeakPolarHBondContact OH-CB 3.42Å; Y319-C327 PolarHBondContact OH-SG 3.16Å; Y319-C327 VanDerWaalsContact OH-SG 3.41Å; Y319-F328 AromaticContact CD1-CE2 3.83Å; Y319-F328 HydrophobicContact CD1-CE2 3.83Å; Y319-F328 AromaticContact CD1-CZ 3.9Å; Y319-F328 HydrophobicContact CD1-CZ 3.9Å; Y319-F328 HydrophobicContact CE1-CD2 4.35Å; Y319-F328 AromaticContact CE1-CE2 3.7Å; Y319-F328 HydrophobicContact CE1-CE2 3.7Å; Y319-F328 HydrophobicContact CE1-CZ 4.12Å; Y319-N376 HydrophobicContact CD2-CB 3.95Å; Y319-N376 WeakPolarHBondContact CD2-OD1 3.38Å; Y319-N376 HydrophobicContact CE2-CB 3.48Å; Y319-N376 VanDerWaalsContact CE2-CB 3.48Å; Y319-N376 VanDerWaalsContact CE2-OD1 3.22Å; Y319-N376 WeakPolarHBondContact CE2-OD1 3.47Å; Y319-V377 HydrophobicContact CD1-CB 4.3Å; Y319-V377 HydrophobicContact CD1-CG2 3.9Å; Y319-V377 HydrophobicContact CE1-CB 3.88Å; Y319-V377 HydrophobicContact CE1-CG2 4Å; Y319-E378 PolarHBondContact OH-OE2 3.02Å
320	Y	83.7	Confident	86.4	Confident	115 Å²	115	83.9 Å²	83.9	45%	0.451	41%	0.407	S	S	.	.			trans	-75.6	90.6	-172.7	-69.2	-98.2	0	0	0	111.1	L317 F328 Y372	L317-Y320 HydrophobicContact CB-CD2 4.26Å; L317-Y320 HydrophobicContact CB-CE2 4.47Å; L317-Y320 HydrophobicContact CD2-CD2 4.18Å; L317-Y320 HydrophobicContact CD2-CE2 3.6Å; Y320-F328 HydrophobicContact CD1-CE1 4.35Å; Y320-F328 AromaticContact CD1-CZ 3.81Å; Y320-F328 HydrophobicContact CD1-CZ 3.81Å; Y320-F328 AromaticContact CE1-CE1 3.87Å; Y320-F328 HydrophobicContact CE1-CE1 3.87Å; Y320-F328 AromaticContact CE1-CZ 3.74Å; Y320-F328 HydrophobicContact CE1-CZ 3.74Å; Y320-F328 HydrophobicContact CG-CZ 4.43Å; Y320-Y372 VanDerWaalsContact CE2-O 3.26Å; Y320-Y372 WeakPolarHBondContact CE2-O 3.34Å; Y320-Y372 PolarHBondContact OH-O 2.95Å
321	Q	85.5	Confident	86.5	Confident	100 Å²	100	78.5 Å²	78.5	47%	0.467	39%	0.387	S	S	.	.			trans	-132	144.7	175.3	-61	-176.8	-5.3	0	0	109.9	Y319 K323 K324	Y319-Q321 PolarHBondContact O-N 3.17Å; Q321-K323 PolarHBondContact O-N 2.89Å; Q321-K323 VanDerWaalsContact O-N 3.15Å; Q321-K324 HydrophobicContact CB-CG 4.44Å; Q321-K324 WeakPolarHBondContact O-CB 3.34Å; Q321-K324 PolarHBondContact O-N 3.39Å
322	W	84.5	Confident	86.7	Confident	232 Å²	232	79.8 Å²	79.8	88%	0.879	40%	0.397	S	S	*	.	G	3₁₀ helix	trans	-55.3	-34.9	177.4	-71.6	106.7	0	0	0	113.2	K324 L325	W322-K324 PolarHBondContact O-N 3.15Å; W322-K324 VanDerWaalsContact O-N 3.15Å; W322-L325 WeakPolarHBondContact O-CB 3.48Å; W322-L325 PolarHBondContact O-N 3.3Å; W322-L325 VanDerWaalsContact O-N 3.17Å
323	K	86.7	Confident	87.1	Confident	185 Å²	185	77.9 Å²	77.9	80%	0.804	40%	0.395	S	S	*	.	G	3₁₀ helix	trans	-61.4	-20.9	176.4	-64.2	-176.1	-179.8	-178.2	0	113.6	Q321	Q321-K323 PolarHBondContact O-N 2.89Å; Q321-K323 VanDerWaalsContact O-N 3.15Å
324	K	87	Confident	87.6	Confident	71 Å²	71	73.4 Å²	73.4	31%	0.309	37%	0.37	S	S	.	.	G	3₁₀ helix	trans	-94.7	2.2	-179.1	-64.2	-62.7	-169	173.8	0	113.5	Y319 Q321 W322 P326 C327 F328	Y319-K324 HydrophobicContact CD2-CG 4.43Å; Y319-K324 HydrophobicContact CE1-CB 3.97Å; Y319-K324 HydrophobicContact CE1-CG 4.3Å; Y319-K324 HydrophobicContact CE2-CB 4.49Å; Y319-K324 HydrophobicContact CE2-CD 3.84Å; Y319-K324 HydrophobicContact CE2-CG 3.96Å; Q321-K324 HydrophobicContact CB-CG 4.44Å; Q321-K324 WeakPolarHBondContact O-CB 3.34Å; Q321-K324 PolarHBondContact O-N 3.39Å; W322-K324 PolarHBondContact O-N 3.15Å; W322-K324 VanDerWaalsContact O-N 3.15Å; K324-P326 VanDerWaalsContact C-N 3.3Å; K324-C327 VanDerWaalsContact O-CB 3.27Å; K324-C327 WeakPolarHBondContact O-CB 3.26Å; K324-C327 PolarHBondContact O-N 2.88Å; K324-F328 HydrophobicContact CB-CE2 4.37Å; K324-F328 WeakPolarHBondContact O-CD2 3.45Å; K324-F328 PolarHBondContact O-N 3.36Å
325	L	90.4	Very high	88.3	Confident	86 Å²	86	74.9 Å²	74.9	45%	0.45	38%	0.376	S	S	.	.	H	α-helix	trans	-50.7	-41.2	177.7	-176.9	64.3	0	0	0	113.8	W322 C327 F328 L329	W322-L325 WeakPolarHBondContact O-CB 3.48Å; W322-L325 PolarHBondContact O-N 3.3Å; W322-L325 VanDerWaalsContact O-N 3.17Å; L325-C327 PolarHBondContact O-N 3.21Å; L325-F328 WeakPolarHBondContact O-CB 3.32Å; L325-F328 PolarHBondContact O-N 2.91Å; L325-F328 VanDerWaalsContact O-N 3.14Å; L325-L329 PolarHBondContact O-N 2.76Å
326	P	91.1	Very high	89	Confident	86 Å²	86	76.5 Å²	76.5	56%	0.558	38%	0.381	S	S	*	.	H	α-helix	trans	-57.6	-36.1	175.6	-26	36.3	0	0	0	113.5	K324 L329 L330	K324-P326 VanDerWaalsContact C-N 3.3Å; P326-L329 PolarHBondContact O-N 3.22Å; P326-L330 WeakPolarHBondContact O-CB 3.13Å; P326-L330 PolarHBondContact O-N 2.96Å
327	C	90.8	Very high	89.5	Confident	25 Å²	25	70.5 Å²	70.5	17%	0.169	35%	0.35	C	S	.	.	H	α-helix	trans	-68.2	-37.7	178.5	-56.8	0	0	0	0	112	Y319 K324 L325 L330 S331 E378	Y319-C327 WeakPolarHBondContact OH-CB 3.42Å; Y319-C327 PolarHBondContact OH-SG 3.16Å; Y319-C327 VanDerWaalsContact OH-SG 3.41Å; K324-C327 VanDerWaalsContact O-CB 3.27Å; K324-C327 WeakPolarHBondContact O-CB 3.26Å; K324-C327 PolarHBondContact O-N 2.88Å; L325-C327 PolarHBondContact O-N 3.21Å; C327-L330 PolarHBondContact O-N 3.1Å; C327-S331 PolarHBondContact O-N 3.49Å; C327-S331 VanDerWaalsContact O-N 3.13Å; C327-E378 HydrophobicContact CB-CB 4.14Å; C327-E378 PolarHBondContact SG-OE2 2.64Å
328	F	92	Very high	90.2	Very high	40 Å²	40	65.8 Å²	65.8	18%	0.175	33%	0.325	C	S	.	.	H	α-helix	trans	-63.3	-45.3	172.6	-76.8	-90.9	0	0	0	111.1	Y319 Y320 K324 L325 L330 S331 L332 Y372 V377	Y319-F328 AromaticContact CD1-CE2 3.83Å; Y319-F328 HydrophobicContact CD1-CE2 3.83Å; Y319-F328 AromaticContact CD1-CZ 3.9Å; Y319-F328 HydrophobicContact CD1-CZ 3.9Å; Y319-F328 HydrophobicContact CE1-CD2 4.35Å; Y319-F328 AromaticContact CE1-CE2 3.7Å; Y319-F328 HydrophobicContact CE1-CE2 3.7Å; Y319-F328 HydrophobicContact CE1-CZ 4.12Å; Y320-F328 HydrophobicContact CD1-CE1 4.35Å; Y320-F328 AromaticContact CD1-CZ 3.81Å; Y320-F328 HydrophobicContact CD1-CZ 3.81Å; Y320-F328 AromaticContact CE1-CE1 3.87Å; Y320-F328 HydrophobicContact CE1-CE1 3.87Å; Y320-F328 AromaticContact CE1-CZ 3.74Å; Y320-F328 HydrophobicContact CE1-CZ 3.74Å; Y320-F328 HydrophobicContact CG-CZ 4.43Å; K324-F328 HydrophobicContact CB-CE2 4.37Å; K324-F328 WeakPolarHBondContact O-CD2 3.45Å; K324-F328 PolarHBondContact O-N 3.36Å; L325-F328 WeakPolarHBondContact O-CB 3.32Å; L325-F328 PolarHBondContact O-N 2.91Å; L325-F328 VanDerWaalsContact O-N 3.14Å; F328-L330 VanDerWaalsContact C-N 3.28Å; F328-L330 PolarHBondContact O-N 3.08Å; F328-S331 PolarHBondContact O-N 3.42Å; F328-S331 VanDerWaalsContact O-N 3.14Å; F328-S331 PolarHBondContact O-OG 3.44Å; F328-L332 PolarHBondContact O-N 3.43Å; F328-Y372 HydrophobicContact CD1-CE1 4.2Å; F328-Y372 HydrophobicContact CE1-CD1 4.35Å; F328-Y372 HydrophobicContact CE1-CE1 4.03Å; F328-V377 HydrophobicContact CD1-CB 4.23Å; F328-V377 HydrophobicContact CD1-CG1 3.85Å; F328-V377 HydrophobicContact CD1-CG2 4.22Å; F328-V377 HydrophobicContact CE1-CB 4.1Å; F328-V377 HydrophobicContact CE1-CG1 4.08Å; F328-V377 HydrophobicContact CE1-CG2 3.6Å; F328-V377 HydrophobicContact CG-CG1 4.39Å; F328-V377 HydrophobicContact CZ-CB 4.34Å; F328-V377 HydrophobicContact CZ-CG2 3.79Å
329	L	93	Very high	91.2	Very high	106 Å²	106	67.1 Å²	67.1	56%	0.555	32%	0.324	S	S	*	.	H	α-helix	trans	-60.3	-38.5	176.3	-65.9	176.2	0	0	0	111.9	L325 P326 S331 L332 P333	L325-L329 PolarHBondContact O-N 2.76Å; P326-L329 PolarHBondContact O-N 3.22Å; L329-S331 VanDerWaalsContact C-N 3.31Å; L329-S331 PolarHBondContact O-N 3.06Å; L329-L332 WeakPolarHBondContact O-CB 3.39Å; L329-L332 PolarHBondContact O-N 3.16Å; L329-P333 WeakPolarHBondContact O-CD 3.47Å
330	L	92.4	Very high	91.9	Very high	39 Å²	39	68.2 Å²	68.2	20%	0.204	33%	0.333	C	S	.	.	H	α-helix	trans	-66.1	-32.5	177.3	-163.9	68.2	0	0	0	112.7	P326 C327 F328 Y437 W451 T452	P326-L330 WeakPolarHBondContact O-CB 3.13Å; P326-L330 PolarHBondContact O-N 2.96Å; C327-L330 PolarHBondContact O-N 3.1Å; F328-L330 VanDerWaalsContact C-N 3.28Å; F328-L330 PolarHBondContact O-N 3.08Å; L330-Y437 HydrophobicContact CD1-CE1 4.16Å; L330-Y437 HydrophobicContact CG-CE1 4.41Å; L330-Y437 WeakPolarHBondContact O-CE1 3.27Å; L330-Y437 PolarHBondContact O-OH 3.43Å; L330-W451 HydrophobicContact CD1-CE3 4.12Å; L330-W451 HydrophobicContact CD1-CH2 4.16Å; L330-W451 HydrophobicContact CD1-CZ3 3.74Å; L330-W451 HydrophobicContact CD2-CE3 4.42Å; L330-T452 HydrophobicContact CD1-CG2 4.49Å; L330-T452 HydrophobicContact CD2-CG2 3.52Å; L330-T452 HydrophobicContact CG-CG2 3.65Å
331	S	94.1	Very high	92.2	Very high	0 Å²	0	62.8 Å²	62.8	0%	0	31%	0.312	C	S	.	.	H	α-helix	trans	-84.2	-18	177	78.5	0	0	0	0	114.1	C327 F328 L329 T334 F335 V377	C327-S331 PolarHBondContact O-N 3.49Å; C327-S331 VanDerWaalsContact O-N 3.13Å; F328-S331 PolarHBondContact O-N 3.42Å; F328-S331 VanDerWaalsContact O-N 3.14Å; F328-S331 PolarHBondContact O-OG 3.44Å; L329-S331 VanDerWaalsContact C-N 3.31Å; L329-S331 PolarHBondContact O-N 3.06Å; S331-T334 WeakPolarHBondContact O-CB 3.37Å; S331-T334 PolarHBondContact O-N 3.25Å; S331-T334 VanDerWaalsContact O-N 3.15Å; S331-F335 PolarHBondContact O-N 3.3Å; S331-F335 VanDerWaalsContact O-N 3.08Å; S331-V377 WeakPolarHBondContact CB-O 3.36Å; S331-V377 WeakPolarHBondContact OG-CG1 3.46Å
332	L	95	Very high	92.5	Very high	78 Å²	78	61.6 Å²	61.6	41%	0.408	31%	0.309	S	S	.	.	H	α-helix	trans	-58.2	-44.5	-168	-179.8	65.4	0	0	0	113.4	F328 L329 T334 F335 C336	F328-L332 PolarHBondContact O-N 3.43Å; L329-L332 WeakPolarHBondContact O-CB 3.39Å; L329-L332 PolarHBondContact O-N 3.16Å; L332-T334 VanDerWaalsContact C-N 3.31Å; L332-T334 PolarHBondContact O-N 2.92Å; L332-F335 PolarHBondContact O-N 3.39Å; L332-F335 VanDerWaalsContact O-N 3.13Å; L332-C336 PolarHBondContact O-N 3.36Å; L332-C336 PolarHBondContact O-SG 2.8Å; L332-C336 VanDerWaalsContact O-SG 3.33Å
333	P	95.8	Very high	92.4	Very high	40 Å²	40	58.8 Å²	58.8	26%	0.26	30%	0.303	S	S	.	.	H	α-helix	trans	-59.5	-40.3	178.1	-26.9	37.4	0	0	0	113.2	L329 C336 L337 W433	L329-P333 WeakPolarHBondContact O-CD 3.47Å; P333-C336 PolarHBondContact O-N 3.09Å; P333-L337 PolarHBondContact O-N 3.08Å; P333-W433 HydrophobicContact CB-CD2 3.71Å; P333-W433 HydrophobicContact CB-CE3 4.38Å; P333-W433 HydrophobicContact CB-CG 3.95Å; P333-W433 HydrophobicContact CB-CH2 4.4Å; P333-W433 HydrophobicContact CB-CZ2 3.76Å
334	T	96.2	Very high	91.7	Very high	0 Å²	0	51.5 Å²	51.5	0%	0	27%	0.273	C	S	.	.	H	α-helix	trans	-62.3	-45.2	175	-55.3	0	0	0	0	110.6	S331 L332 L337 F338 L380 T381 L384 F385 L391 W433	S331-T334 WeakPolarHBondContact O-CB 3.37Å; S331-T334 PolarHBondContact O-N 3.25Å; S331-T334 VanDerWaalsContact O-N 3.15Å; L332-T334 VanDerWaalsContact C-N 3.31Å; L332-T334 PolarHBondContact O-N 2.92Å; T334-L337 PolarHBondContact O-N 3.33Å; T334-F338 WeakPolarHBondContact O-CB 3.48Å; T334-F338 PolarHBondContact O-N 3.42Å; T334-L380 HydrophobicContact CG2-CG 4.39Å; T334-T381 PolarHBondContact OG1-OG1 3.04Å; T334-L384 HydrophobicContact CG2-CB 4.39Å; T334-L384 HydrophobicContact CG2-CD1 3.93Å; T334-F385 HydrophobicContact CG2-CE2 4.24Å; T334-L391 HydrophobicContact CG2-CD1 3.78Å; T334-W433 WeakPolarHBondContact OG1-CZ2 3.41Å
335	F	96.2	Very high	90.5	Very high	49 Å²	49	57.5 Å²	57.5	22%	0.215	30%	0.299	C	S	.	.	H	α-helix	trans	-63.4	-43.6	178.2	-175.6	-115.7	0	0	0	111.9	S331 L332 L337 F338 L339 V368 Y372 L380	S331-F335 PolarHBondContact O-N 3.3Å; S331-F335 VanDerWaalsContact O-N 3.08Å; L332-F335 PolarHBondContact O-N 3.39Å; L332-F335 VanDerWaalsContact O-N 3.13Å; F335-L337 PolarHBondContact O-N 3.21Å; F335-F338 HydrophobicContact CD2-CD1 4.28Å; F335-F338 HydrophobicContact CE2-CD1 4.33Å; F335-F338 WeakPolarHBondContact O-CB 3.37Å; F335-F338 PolarHBondContact O-N 2.93Å; F335-L339 HydrophobicContact CD1-CD1 3.93Å; F335-L339 HydrophobicContact CD1-CG 4.33Å; F335-L339 HydrophobicContact CE1-CD1 3.53Å; F335-L339 HydrophobicContact CE1-CD2 4.41Å; F335-L339 HydrophobicContact CE1-CG 4.03Å; F335-L339 HydrophobicContact CE2-CD2 4.31Å; F335-L339 HydrophobicContact CE2-CG 4.35Å; F335-L339 HydrophobicContact CZ-CD1 3.97Å; F335-L339 HydrophobicContact CZ-CD2 3.98Å; F335-L339 HydrophobicContact CZ-CG 4.03Å; F335-L339 WeakPolarHBondContact O-CG 3.32Å; F335-L339 PolarHBondContact O-N 3.27Å; F335-V368 HydrophobicContact CD2-CG1 4.03Å; F335-V368 HydrophobicContact CE2-CG1 3.71Å; F335-Y372 AromaticContact CD2-CE2 3.79Å; F335-Y372 HydrophobicContact CD2-CE2 3.79Å; F335-Y372 HydrophobicContact CE2-CE2 4.05Å; F335-Y372 HydrophobicContact CG-CE2 4.34Å; F335-L380 HydrophobicContact CB-CD2 4Å; F335-L380 HydrophobicContact CD2-CD2 4.46Å
336	C	95.7	Very high	89.1	Confident	65 Å²	65	54.9 Å²	54.9	44%	0.439	28%	0.284	S	S	.	.	H	α-helix	trans	-61.4	-42.9	175.1	-70	0	0	0	0	112.2	L332 P333 F338 L339 S340	L332-C336 PolarHBondContact O-N 3.36Å; L332-C336 PolarHBondContact O-SG 2.8Å; L332-C336 VanDerWaalsContact O-SG 3.33Å; P333-C336 PolarHBondContact O-N 3.09Å; C336-F338 VanDerWaalsContact C-N 3.33Å; C336-F338 PolarHBondContact O-N 3.26Å; C336-L339 PolarHBondContact O-N 3.29Å; C336-S340 PolarHBondContact O-N 3.02Å
337	L	95.2	Very high	87.3	Confident	10 Å²	10	55.2 Å²	55.2	5%	0.052	29%	0.286	C	S	.	.	H	α-helix	trans	-63	-42.1	175.1	-175.2	65.6	0	0	0	110.9	P333 T334 F335 S340 S341 F385 L391 Q394 A395 L398 W433 F434	P333-L337 PolarHBondContact O-N 3.08Å; T334-L337 PolarHBondContact O-N 3.33Å; F335-L337 PolarHBondContact O-N 3.21Å; L337-S340 PolarHBondContact O-N 2.59Å; L337-S340 PolarHBondContact O-OG 3.18Å; L337-S341 PolarHBondContact O-N 3.24Å; L337-F385 HydrophobicContact CD2-CZ 4.39Å; L337-L391 HydrophobicContact CB-CD2 4.23Å; L337-L391 HydrophobicContact CD2-CB 4.18Å; L337-L391 HydrophobicContact CD2-CD2 3.94Å; L337-L391 HydrophobicContact CG-CD2 3.89Å; L337-Q394 HydrophobicContact CD1-CB 4.48Å; L337-Q394 HydrophobicContact CD1-CG 3.79Å; L337-Q394 HydrophobicContact CG-CG 4.31Å; L337-A395 HydrophobicContact CD1-CB 4.4Å; L337-A395 HydrophobicContact CD2-CB 4.04Å; L337-L398 HydrophobicContact CD1-CD1 3.91Å; L337-W433 HydrophobicContact CB-CZ3 4.4Å; L337-W433 HydrophobicContact CD2-CH2 4.33Å; L337-W433 HydrophobicContact CD2-CZ3 3.85Å; L337-F434 HydrophobicContact CD2-CE2 4.41Å
338	F	95.9	Very high	85.6	Confident	8 Å²	8	55.3 Å²	55.3	4%	0.035	28%	0.284	C	S	.	.	H	α-helix	trans	-60.8	-47.6	173.6	165.4	-101.8	0	0	0	112	T334 F335 C336 S340 S341 L342 L361 C365 V368 L384 L391	T334-F338 WeakPolarHBondContact O-CB 3.48Å; T334-F338 PolarHBondContact O-N 3.42Å; F335-F338 HydrophobicContact CD2-CD1 4.28Å; F335-F338 HydrophobicContact CE2-CD1 4.33Å; F335-F338 WeakPolarHBondContact O-CB 3.37Å; F335-F338 PolarHBondContact O-N 2.93Å; C336-F338 VanDerWaalsContact C-N 3.33Å; C336-F338 PolarHBondContact O-N 3.26Å; F338-S340 VanDerWaalsContact C-N 3.26Å; F338-S340 PolarHBondContact O-N 3.22Å; F338-S341 WeakPolarHBondContact O-CA 3.38Å; F338-S341 VanDerWaalsContact O-CB 3.27Å; F338-S341 WeakPolarHBondContact O-CB 3.49Å; F338-S341 PolarHBondContact O-N 3.18Å; F338-S341 PolarHBondContact O-OG 3.46Å; F338-L342 HydrophobicContact CE1-CD1 4.36Å; F338-L342 HydrophobicContact CZ-CD2 4.24Å; F338-L361 HydrophobicContact CE2-CD1 4.33Å; F338-C365 HydrophobicContact CZ-CB 4.28Å; F338-V368 HydrophobicContact CD1-CB 4.49Å; F338-V368 HydrophobicContact CD1-CG1 4.28Å; F338-V368 HydrophobicContact CD1-CG2 3.73Å; F338-V368 HydrophobicContact CD2-CG2 4.12Å; F338-V368 HydrophobicContact CE1-CB 4.13Å; F338-V368 HydrophobicContact CE1-CG1 4Å; F338-V368 HydrophobicContact CE1-CG2 3.76Å; F338-V368 HydrophobicContact CE2-CG2 4.15Å; F338-V368 HydrophobicContact CG-CG2 3.91Å; F338-V368 HydrophobicContact CZ-CB 4.37Å; F338-V368 HydrophobicContact CZ-CG2 3.97Å; F338-L384 HydrophobicContact CB-CD1 4.41Å; F338-L391 HydrophobicContact CB-CD2 4.09Å
339	L	95.2	Very high	83.6	Confident	61 Å²	61	60.8 Å²	60.8	32%	0.319	32%	0.315	S	S	.	.	H	α-helix	trans	-58.4	-40.1	177.7	-73.4	179.4	0	0	0	111.7	F335 C336 S341 L342 F343	F335-L339 HydrophobicContact CD1-CD1 3.93Å; F335-L339 HydrophobicContact CD1-CG 4.33Å; F335-L339 HydrophobicContact CE1-CD1 3.53Å; F335-L339 HydrophobicContact CE1-CD2 4.41Å; F335-L339 HydrophobicContact CE1-CG 4.03Å; F335-L339 HydrophobicContact CE2-CD2 4.31Å; F335-L339 HydrophobicContact CE2-CG 4.35Å; F335-L339 HydrophobicContact CZ-CD1 3.97Å; F335-L339 HydrophobicContact CZ-CD2 3.98Å; F335-L339 HydrophobicContact CZ-CG 4.03Å; F335-L339 WeakPolarHBondContact O-CG 3.32Å; F335-L339 PolarHBondContact O-N 3.27Å; C336-L339 PolarHBondContact O-N 3.29Å; L339-S341 PolarHBondContact O-N 3.11Å; L339-S341 VanDerWaalsContact O-N 3.14Å; L339-L342 HydrophobicContact CD2-CD1 3.79Å; L339-L342 WeakPolarHBondContact O-CB 3.48Å; L339-L342 PolarHBondContact O-N 3.3Å; L339-F343 VanDerWaalsContact O-CD2 3.23Å; L339-F343 WeakPolarHBondContact O-CD2 3.4Å; L339-F343 WeakPolarHBondContact O-CE2 3.08Å
340	S	92.5	Very high	82.2	Confident	36 Å²	36	58.1 Å²	58.1	25%	0.252	31%	0.313	S	S	.	.	H	α-helix	trans	-60.1	-25.5	175.8	81	0	0	0	0	112.7	C336 L337 F338 L342 Q394	C336-S340 PolarHBondContact O-N 3.02Å; L337-S340 PolarHBondContact O-N 2.59Å; L337-S340 PolarHBondContact O-OG 3.18Å; F338-S340 VanDerWaalsContact C-N 3.26Å; F338-S340 PolarHBondContact O-N 3.22Å; S340-L342 VanDerWaalsContact C-N 3.32Å; S340-L342 PolarHBondContact O-N 3.37Å; S340-Q394 PolarHBondContact O-NE2 3.11Å; S340-Q394 WeakPolarHBondContact OG-CG 3.42Å; S340-Q394 PolarHBondContact OG-NE2 3.25Å
341	S	91.4	Very high	81.3	Confident	1 Å²	1	62.1 Å²	62.1	1%	0.007	33%	0.33	C	S	.	.	H	α-helix	trans	-73.1	-21.1	176.8	80.2	0	0	0	0	114.5	L337 F338 L339 F343 L361	L337-S341 PolarHBondContact O-N 3.24Å; F338-S341 WeakPolarHBondContact O-CA 3.38Å; F338-S341 VanDerWaalsContact O-CB 3.27Å; F338-S341 WeakPolarHBondContact O-CB 3.49Å; F338-S341 PolarHBondContact O-N 3.18Å; F338-S341 PolarHBondContact O-OG 3.46Å; L339-S341 PolarHBondContact O-N 3.11Å; L339-S341 VanDerWaalsContact O-N 3.14Å; S341-F343 VanDerWaalsContact C-N 3.32Å; S341-F343 PolarHBondContact O-N 3.37Å; S341-L361 VanDerWaalsContact OG-CD1 3.31Å; S341-L361 WeakPolarHBondContact OG-CD1 3.24Å
342	L	91	Very high	80.5	Confident	75 Å²	75	64.2 Å²	64.2	39%	0.393	34%	0.343	S	S	.	.	H	α-helix	trans	-71.8	-26.3	177	-61.1	169.9	0	0	0	112.6	F338 L339 S340 L361	F338-L342 HydrophobicContact CE1-CD1 4.36Å; F338-L342 HydrophobicContact CZ-CD2 4.24Å; L339-L342 HydrophobicContact CD2-CD1 3.79Å; L339-L342 WeakPolarHBondContact O-CB 3.48Å; L339-L342 PolarHBondContact O-N 3.3Å; S340-L342 VanDerWaalsContact C-N 3.32Å; S340-L342 PolarHBondContact O-N 3.37Å; L342-L361 HydrophobicContact CD2-CD1 3.76Å; L342-L361 HydrophobicContact CD2-CD2 4.1Å; L342-L361 HydrophobicContact CD2-CG 4.04Å; L342-L361 HydrophobicContact CG-CD1 4.5Å
343	F	83.1	Confident	79.8	Confident	174 Å²	174	64.1 Å²	64.1	76%	0.763	34%	0.337	S	S	*	.	T	Hydrogen-bonded Turn	trans	-92.4	7.2	-173.8	-62	-75.5	0	0	0	114.1	L339 S341 K345	L339-F343 VanDerWaalsContact O-CD2 3.23Å; L339-F343 WeakPolarHBondContact O-CD2 3.4Å; L339-F343 WeakPolarHBondContact O-CE2 3.08Å; S341-F343 VanDerWaalsContact C-N 3.32Å; S341-F343 PolarHBondContact O-N 3.37Å; F343-K345 PolarHBondContact O-N 3.39Å
344	I	71	Confident	79	Confident	31 Å²	31	67 Å²	67	16%	0.159	34%	0.343	C	S	.	.			trans	-79.4	122.7	-173	-59	175.3	0	0	0	111.2	F346 W393	I344-F346 HydrophobicContact CB-CE1 4.48Å; I344-F346 HydrophobicContact CG2-CD1 4.02Å; I344-F346 HydrophobicContact CG2-CE1 4.24Å; I344-F346 PolarHBondContact O-N 3.03Å; I344-W393 HydrophobicContact CD1-CE3 4.33Å; I344-W393 HydrophobicContact CD1-CH2 4.25Å; I344-W393 HydrophobicContact CD1-CZ3 3.46Å; I344-W393 VanDerWaalsContact CD1-CZ3 3.46Å; I344-W393 HydrophobicContact CG2-CH2 4.08Å; I344-W393 HydrophobicContact CG2-CZ3 4.26Å
345	K	61.7	Low	78.5	Confident	197 Å²	197	69.3 Å²	69.3	86%	0.857	36%	0.355	S	S	*	.			trans	-79.1	99.9	162.2	-69.9	-172.2	179.1	-178.7	0	108.9	F343 P347	F343-K345 PolarHBondContact O-N 3.39Å; K345-P347 WeakPolarHBondContact O-CD 3.45Å
346	F	61.1	Low	78.1	Confident	32 Å²	32	67 Å²	67	14%	0.14	35%	0.346	C	S	.	.			trans	-59.7	102.7	-177.8	-61.5	-67.3	0	0	0	112.8	I344 L348 R354 Q357 W393	I344-F346 HydrophobicContact CB-CE1 4.48Å; I344-F346 HydrophobicContact CG2-CD1 4.02Å; I344-F346 HydrophobicContact CG2-CE1 4.24Å; I344-F346 PolarHBondContact O-N 3.03Å; F346-L348 VanDerWaalsContact C-N 3.26Å; F346-L348 PolarHBondContact O-N 2.89Å; F346-L348 VanDerWaalsContact O-N 3.09Å; F346-R354 HydrophobicContact CB-CG 3.97Å; F346-R354 HydrophobicContact CD2-CG 4.09Å; F346-R354 HydrophobicContact CG-CG 4.26Å; F346-R354 PolarHBondContact O-NH2 2.9Å; F346-Q357 HydrophobicContact CD1-CB 4.11Å; F346-Q357 HydrophobicContact CE1-CB 3.67Å; F346-Q357 HydrophobicContact CE1-CG 4.4Å; F346-Q357 HydrophobicContact CZ-CB 4.09Å; F346-W393 HydrophobicContact CD1-CH2 4.45Å
347	P	53.8	Low	77.6	Confident	93 Å²	93	64.1 Å²	64.1	60%	0.604	33%	0.325	S	S	*	.			trans	-90.5	68.9	177.7	32.1	-16.5	0	0	0	107.1	K345	K345-P347 WeakPolarHBondContact O-CD 3.45Å
348	L	54.6	Low	77.3	Confident	26 Å²	26	66 Å²	66	14%	0.136	34%	0.34	C	S	.	.			trans	-119.9	139	-177.7	-73.7	-170.6	0	0	0	112.8	L132 F346 G350 R353 Q357	L132-L348 WeakPolarHBondContact O-CD1 3.34Å; F346-L348 VanDerWaalsContact C-N 3.26Å; F346-L348 PolarHBondContact O-N 2.89Å; F346-L348 VanDerWaalsContact O-N 3.09Å; L348-G350 PolarHBondContact O-N 2.87Å; L348-R353 HydrophobicContact CD1-CB 3.98Å; L348-Q357 HydrophobicContact CD1-CG 4.27Å
349	L	50.6	Low	77.1	Confident	156 Å²	156	66 Å²	66	82%	0.817	34%	0.34	S	S	*	.	S	Bend	trans	-66.1	103.5	170.5	-77.5	150.2	0	0	0	109.8
350	G	62.8	Low	77	Confident	49 Å²	49	63.3 Å²	63.3	51%	0.505	33%	0.326	S	S	.	.	S	Bend	trans	100.7	137.3	166.8	0	0	0	0	0	115.5	L348 T352 R353	L348-G350 PolarHBondContact O-N 2.87Å; G350-T352 VanDerWaalsContact C-N 3.29Å; G350-T352 PolarHBondContact O-N 2.76Å; G350-R353 PolarHBondContact O-N 2.75Å
351	Q	74.1	Confident	77	Confident	123 Å²	123	62.9 Å²	62.9	58%	0.575	32%	0.321	S	S	*	.	H	α-helix	trans	-55.2	-39.5	-175.3	-168.9	64.3	30.2	0	0	113.4	R353 R354 N355	Q351-R353 PolarHBondContact O-N 3.18Å; Q351-R354 PolarHBondContact O-N 2.98Å; Q351-N355 PolarHBondContact NE2-OD1 2.94Å; Q351-N355 PolarHBondContact O-N 2.84Å; Q351-N355 PolarHBondContact O-OD1 3.32Å
352	T	77.9	Confident	77.1	Confident	45 Å²	45	67.4 Å²	67.4	28%	0.276	34%	0.344	S	S	.	.	H	α-helix	trans	-58.7	-46.4	-178.3	-61.5	0	0	0	0	112.8	Q211 G350 N355 I356	Q211-T352 PolarHBondContact NE2-OG1 2.95Å; G350-T352 VanDerWaalsContact C-N 3.29Å; G350-T352 PolarHBondContact O-N 2.76Å; T352-N355 PolarHBondContact O-N 2.99Å; T352-I356 HydrophobicContact CG2-CD1 3.96Å; T352-I356 WeakPolarHBondContact O-CG1 3.3Å; T352-I356 PolarHBondContact O-N 2.03Å; T352-I356 VanDerWaalsContact O-N 3.09Å
353	R	79.9	Confident	77.3	Confident	75 Å²	75	63.9 Å²	63.9	28%	0.283	33%	0.326	S	S	.	.	H	α-helix	trans	-68.4	-41.9	-176.2	-69.3	176.1	173.9	-176.3	5.3	111.2	F131 L132 L348 G350 Q351 N355 I356 Q357	F131-R353 PolarHBondContact O-NE 3.46Å; F131-R353 VanDerWaalsContact O-NE 3.11Å; L132-R353 WeakPolarHBondContact O-CD 3.25Å; L348-R353 HydrophobicContact CD1-CB 3.98Å; G350-R353 PolarHBondContact O-N 2.75Å; Q351-R353 PolarHBondContact O-N 3.18Å; R353-N355 VanDerWaalsContact C-N 3.31Å; R353-N355 PolarHBondContact O-N 3.32Å; R353-I356 PolarHBondContact O-N 3.49Å; R353-Q357 PolarHBondContact O-N 3.28Å
354	R	79.8	Confident	77.9	Confident	101 Å²	101	55.7 Å²	55.7	38%	0.381	29%	0.29	S	S	.	.	H	α-helix	trans	-59.4	-42	174.5	-173.6	179.4	-72.6	174	-4.5	111.8	F346 Q351 Q357 S358	F346-R354 HydrophobicContact CB-CG 3.97Å; F346-R354 HydrophobicContact CD2-CG 4.09Å; F346-R354 HydrophobicContact CG-CG 4.26Å; F346-R354 PolarHBondContact O-NH2 2.9Å; Q351-R354 PolarHBondContact O-N 2.98Å; R354-Q357 PolarHBondContact O-N 2.91Å; R354-S358 PolarHBondContact O-N 3.39Å; R354-S358 PolarHBondContact O-OG 2.94Å
355	N	84.4	Confident	79.1	Confident	48 Å²	48	55.9 Å²	55.9	26%	0.257	29%	0.294	S	S	.	.	H	α-helix	trans	-65.5	-39.2	177.9	-66.2	-4.2	0	0	0	111.9	F207 Q351 T352 R353 S358 L359	F207-N355 HydrophobicContact CE2-CB 3.76Å; F207-N355 HydrophobicContact CZ-CB 3.45Å; F207-N355 VanDerWaalsContact CZ-CB 3.45Å; Q351-N355 PolarHBondContact NE2-OD1 2.94Å; Q351-N355 PolarHBondContact O-N 2.84Å; Q351-N355 PolarHBondContact O-OD1 3.32Å; T352-N355 PolarHBondContact O-N 2.99Å; R353-N355 VanDerWaalsContact C-N 3.31Å; R353-N355 PolarHBondContact O-N 3.32Å; N355-S358 WeakPolarHBondContact O-CB 3.45Å; N355-S358 PolarHBondContact O-N 3.43Å; N355-L359 WeakPolarHBondContact O-CB 3.23Å; N355-L359 PolarHBondContact O-N 3.4Å
356	I	87.6	Confident	80.7	Confident	2 Å²	2	51.8 Å²	51.8	1%	0.01	28%	0.276	C	S	.	.	H	α-helix	trans	-68.4	-37.5	177.8	-63	165.4	0	0	0	111.4	F131 L132 F176 F207 T352 R353 L359 L360	F131-I356 HydrophobicContact CE1-CD1 3.62Å; F131-I356 HydrophobicContact CZ-CD1 4.31Å; L132-I356 HydrophobicContact CD2-CB 3.95Å; L132-I356 HydrophobicContact CD2-CG2 3.49Å; L132-I356 VanDerWaalsContact CD2-CG2 3.49Å; F176-I356 HydrophobicContact CB-CD1 4.09Å; F176-I356 HydrophobicContact CD1-CD1 3.63Å; F176-I356 HydrophobicContact CD1-CG1 3.96Å; F176-I356 HydrophobicContact CD1-CG2 4.47Å; F176-I356 HydrophobicContact CD2-CG2 4.07Å; F176-I356 HydrophobicContact CE1-CD1 4.2Å; F176-I356 HydrophobicContact CE1-CG1 4Å; F176-I356 HydrophobicContact CE1-CG2 4.3Å; F176-I356 HydrophobicContact CE2-CG2 3.87Å; F176-I356 HydrophobicContact CG-CD1 3.86Å; F176-I356 HydrophobicContact CG-CG1 4.45Å; F176-I356 HydrophobicContact CG-CG2 4.38Å; F176-I356 HydrophobicContact CZ-CG2 4Å; F207-I356 HydrophobicContact CE1-CG1 3.81Å; F207-I356 HydrophobicContact CZ-CG1 4.19Å; T352-I356 HydrophobicContact CG2-CD1 3.96Å; T352-I356 WeakPolarHBondContact O-CG1 3.3Å; T352-I356 PolarHBondContact O-N 2.03Å; T352-I356 VanDerWaalsContact O-N 3.09Å; R353-I356 PolarHBondContact O-N 3.49Å; I356-L359 WeakPolarHBondContact O-CB 3.07Å; I356-L359 PolarHBondContact O-N 2.93Å; I356-L360 WeakPolarHBondContact O-CG 3.05Å; I356-L360 PolarHBondContact O-N 3.23Å
357	Q	86.3	Confident	82.4	Confident	3 Å²	3	50.4 Å²	50.4	1%	0.014	27%	0.271	C	S	.	.	H	α-helix	trans	-64.4	-41.2	172.7	-71.4	-175.8	-42.1	0	0	112.3	F346 L348 R353 R354 L359 L360 L361	F346-Q357 HydrophobicContact CD1-CB 4.11Å; F346-Q357 HydrophobicContact CE1-CB 3.67Å; F346-Q357 HydrophobicContact CE1-CG 4.4Å; F346-Q357 HydrophobicContact CZ-CB 4.09Å; L348-Q357 HydrophobicContact CD1-CG 4.27Å; R353-Q357 PolarHBondContact O-N 3.28Å; R354-Q357 PolarHBondContact O-N 2.91Å; Q357-L359 PolarHBondContact O-N 2.86Å; Q357-L360 PolarHBondContact O-N 3.4Å; Q357-L360 VanDerWaalsContact O-N 3.16Å; Q357-L361 PolarHBondContact O-N 2.85Å
358	S	88.2	Confident	84.4	Confident	51 Å²	51	46.4 Å²	46.4	36%	0.357	24%	0.244	S	C	.	.	H	α-helix	trans	-61.1	-34.2	174.9	-54.5	0	0	0	0	111.6	R354 N355 L361 L362	R354-S358 PolarHBondContact O-N 3.39Å; R354-S358 PolarHBondContact O-OG 2.94Å; N355-S358 WeakPolarHBondContact O-CB 3.45Å; N355-S358 PolarHBondContact O-N 3.43Å; S358-L361 WeakPolarHBondContact O-CB 3.39Å; S358-L361 PolarHBondContact O-N 2.88Å; S358-L362 WeakPolarHBondContact O-CB 3.21Å; S358-L362 PolarHBondContact O-N 3.03Å
359	L	91.8	Very high	86.3	Confident	7 Å²	7	49.2 Å²	49.2	4%	0.037	27%	0.265	C	S	.	.	H	α-helix	trans	-70	-41.4	174.1	178.4	68.7	0	0	0	112.9	F176 L203 F204 F207 N355 I356 Q357 L361 L362 H363	F176-L359 HydrophobicContact CE1-CD2 4.28Å; F176-L359 HydrophobicContact CZ-CD2 3.82Å; L203-L359 HydrophobicContact CD1-CD1 4.39Å; L203-L359 HydrophobicContact CD2-CD1 4.19Å; L203-L359 HydrophobicContact CG-CD1 3.81Å; F204-L359 HydrophobicContact CD1-CD2 3.5Å; F204-L359 VanDerWaalsContact CD1-CD2 3.5Å; F204-L359 HydrophobicContact CD1-CG 3.79Å; F204-L359 HydrophobicContact CE1-CD2 4.08Å; F204-L359 HydrophobicContact CE1-CG 3.95Å; F207-L359 HydrophobicContact CB-CD1 3.58Å; F207-L359 HydrophobicContact CB-CD2 3.49Å; F207-L359 VanDerWaalsContact CB-CD2 3.49Å; F207-L359 HydrophobicContact CB-CG 4.12Å; F207-L359 HydrophobicContact CD1-CD2 3.35Å; F207-L359 HydrophobicContact CD2-CB 4.22Å; F207-L359 HydrophobicContact CD2-CD1 4.06Å; F207-L359 HydrophobicContact CD2-CD2 3.94Å; F207-L359 HydrophobicContact CD2-CG 4.32Å; F207-L359 HydrophobicContact CE1-CD2 4.03Å; F207-L359 HydrophobicContact CE2-CB 4.46Å; F207-L359 HydrophobicContact CG-CB 4.38Å; F207-L359 HydrophobicContact CG-CD1 3.91Å; F207-L359 HydrophobicContact CG-CD2 3.3Å; F207-L359 HydrophobicContact CG-CG 4.07Å; N355-L359 WeakPolarHBondContact O-CB 3.23Å; N355-L359 PolarHBondContact O-N 3.4Å; I356-L359 WeakPolarHBondContact O-CB 3.07Å; I356-L359 PolarHBondContact O-N 2.93Å; Q357-L359 PolarHBondContact O-N 2.86Å; L359-L361 PolarHBondContact O-N 3.46Å; L359-L362 PolarHBondContact O-N 3.41Å; L359-H363 VanDerWaalsContact O-CB 3.28Å; L359-H363 WeakPolarHBondContact O-CB 3.44Å; L359-H363 PolarHBondContact O-N 3.14Å
360	L	93.6	Very high	88.3	Confident	4 Å²	4	45.9 Å²	45.9	2%	0.021	24%	0.242	C	C	.	.	H	α-helix	trans	-62.4	-35.9	173	-68.5	173.4	0	0	0	111.3	L132 M172 F204 I356 Q357 S364 P389 L390	L132-L360 HydrophobicContact CD1-CD1 3.59Å; M172-L360 HydrophobicContact CE-CD2 4.45Å; M172-L360 HydrophobicContact SD-CD2 4.21Å; F204-L360 HydrophobicContact CE1-CD2 3.83Å; F204-L360 HydrophobicContact CZ-CD2 3.99Å; I356-L360 WeakPolarHBondContact O-CG 3.05Å; I356-L360 PolarHBondContact O-N 3.23Å; Q357-L360 PolarHBondContact O-N 3.4Å; Q357-L360 VanDerWaalsContact O-N 3.16Å; L360-S364 WeakPolarHBondContact O-CB 3.32Å; L360-S364 PolarHBondContact O-N 3.33Å; L360-S364 PolarHBondContact O-OG 3.46Å; L360-P389 HydrophobicContact CD1-CG 4.23Å; L360-P389 HydrophobicContact CD2-CG 4.4Å; L360-L390 HydrophobicContact CB-CB 4.43Å
361	L	93.4	Very high	89.8	Confident	27 Å²	27	43.6 Å²	43.6	14%	0.141	22%	0.218	C	C	.	.	H	α-helix	trans	-64.1	-52.2	172.8	-169	63	0	0	0	110.8	F338 S341 L342 Q357 S358 L359 H363 S364 C365 L390	F338-L361 HydrophobicContact CE2-CD1 4.33Å; S341-L361 VanDerWaalsContact OG-CD1 3.31Å; S341-L361 WeakPolarHBondContact OG-CD1 3.24Å; L342-L361 HydrophobicContact CD2-CD1 3.76Å; L342-L361 HydrophobicContact CD2-CD2 4.1Å; L342-L361 HydrophobicContact CD2-CG 4.04Å; L342-L361 HydrophobicContact CG-CD1 4.5Å; Q357-L361 PolarHBondContact O-N 2.85Å; S358-L361 WeakPolarHBondContact O-CB 3.39Å; S358-L361 PolarHBondContact O-N 2.88Å; L359-L361 PolarHBondContact O-N 3.46Å; L361-H363 VanDerWaalsContact C-N 3.32Å; L361-H363 PolarHBondContact O-N 3.46Å; L361-S364 CarbonylContact O-C 3.58Å; L361-S364 PolarHBondContact O-N 2.97Å; L361-S364 VanDerWaalsContact O-N 3.08Å; L361-C365 PolarHBondContact O-N 2.84Å; L361-C365 PolarHBondContact O-SG 2.87Å; L361-L390 HydrophobicContact CD1-CD2 3.89Å
362	L	93.2	Very high	90.7	Very high	96 Å²	96	39.9 Å²	39.9	50%	0.503	20%	0.199	S	C	.	.	H	α-helix	trans	-56.7	-45.2	177.4	179.3	63.6	0	0	0	112.2	L203 S358 L359 S364 C365 F366	L203-L362 HydrophobicContact CD1-CD2 4.26Å; L203-L362 HydrophobicContact CD2-CD2 4.09Å; L203-L362 HydrophobicContact CD2-CG 4.08Å; S358-L362 WeakPolarHBondContact O-CB 3.21Å; S358-L362 PolarHBondContact O-N 3.03Å; L359-L362 PolarHBondContact O-N 3.41Å; L362-S364 VanDerWaalsContact C-N 3.33Å; L362-S364 PolarHBondContact O-N 3.15Å; L362-C365 WeakPolarHBondContact O-CB 3.35Å; L362-C365 PolarHBondContact O-N 3.34Å; L362-F366 PolarHBondContact O-N 3.32Å
363	H	95.3	Very high	91.4	Very high	1 Å²	1	39.1 Å²	39.1	1%	0.005	20%	0.198	C	C	.	.	H	α-helix	trans	-57.9	-45.4	175.2	178.6	-88.4	0	0	0	111.6	V200 L203 F204 L359 L361 F366 L367	V200-H363 WeakPolarHBondContact CG1-CD2 3.35Å; L203-H363 HydrophobicContact CD2-CB 4.19Å; F204-H363 HydrophobicContact CE1-CB 4.33Å; F204-H363 AromaticContact CE2-CD2 3.63Å; F204-H363 AromaticContact CE2-NE2 3.72Å; F204-H363 HydrophobicContact CZ-CB 4.06Å; F204-H363 AromaticContact CZ-CD2 3.47Å; F204-H363 VanDerWaalsContact CZ-CD2 3.47Å; F204-H363 WeakPolarHBondContact CZ-CD2 3.49Å; F204-H363 AromaticContact CZ-CG 3.66Å; F204-H363 AromaticContact CZ-NE2 3.88Å; L359-H363 VanDerWaalsContact O-CB 3.28Å; L359-H363 WeakPolarHBondContact O-CB 3.44Å; L359-H363 PolarHBondContact O-N 3.14Å; L361-H363 VanDerWaalsContact C-N 3.32Å; L361-H363 PolarHBondContact O-N 3.46Å; H363-F366 PolarHBondContact O-N 3.45Å; H363-L367 VanDerWaalsContact CE1-CD1 3.49Å; H363-L367 WeakPolarHBondContact CE1-CD1 3.44Å; H363-L367 WeakPolarHBondContact O-CG 3.41Å; H363-L367 PolarHBondContact O-N 3.36Å; H363-L367 VanDerWaalsContact O-N 3.15Å
364	S	95.4	Very high	91.9	Very high	2 Å²	2	37.3 Å²	37.3	1%	0.014	20%	0.196	C	C	.	.	H	α-helix	trans	-71.4	-36.7	179.6	-51.3	0	0	0	0	111.9	L360 L361 L362 F366 L367 V368 S388 L390	L360-S364 WeakPolarHBondContact O-CB 3.32Å; L360-S364 PolarHBondContact O-N 3.33Å; L360-S364 PolarHBondContact O-OG 3.46Å; L361-S364 CarbonylContact O-C 3.58Å; L361-S364 PolarHBondContact O-N 2.97Å; L361-S364 VanDerWaalsContact O-N 3.08Å; L362-S364 VanDerWaalsContact C-N 3.33Å; L362-S364 PolarHBondContact O-N 3.15Å; S364-F366 VanDerWaalsContact C-N 3.34Å; S364-F366 PolarHBondContact O-N 3.48Å; S364-L367 PolarHBondContact O-N 2.92Å; S364-V368 WeakPolarHBondContact O-CB 3.43Å; S364-V368 VanDerWaalsContact O-CG2 3.24Å; S364-V368 WeakPolarHBondContact O-CG2 3.46Å; S364-V368 PolarHBondContact O-N 2.97Å; S364-S388 PolarHBondContact OG-OG 2.95Å; S364-L390 WeakPolarHBondContact OG-CD2 3.1Å
365	C	95.6	Very high	92.4	Very high	36 Å²	36	32.9 Å²	32.9	24%	0.243	18%	0.181	C	C	.	.	H	α-helix	trans	-57.9	-46.9	171.8	-67.7	0	0	0	0	111.1	F338 L361 L362 L367 V368 C369	F338-C365 HydrophobicContact CZ-CB 4.28Å; L361-C365 PolarHBondContact O-N 2.84Å; L361-C365 PolarHBondContact O-SG 2.87Å; L362-C365 WeakPolarHBondContact O-CB 3.35Å; L362-C365 PolarHBondContact O-N 3.34Å; C365-L367 VanDerWaalsContact C-N 3.34Å; C365-L367 PolarHBondContact O-N 2.91Å; C365-V368 PolarHBondContact O-N 2.86Å; C365-C369 WeakPolarHBondContact O-CB 3.21Å; C365-C369 PolarHBondContact O-N 3.42Å; C365-C369 PolarHBondContact O-SG 2.85Å
366	F	95.8	Very high	92.7	Very high	110 Å²	110	31.4 Å²	31.4	48%	0.482	17%	0.173	S	C	.	.	H	α-helix	trans	-58	-47.8	177.1	175.7	-92.3	0	0	0	111.3	V200 L362 H363 S364 C369 Y370	V200-F366 HydrophobicContact CB-CD1 4.49Å; V200-F366 HydrophobicContact CG1-CD1 3.64Å; V200-F366 HydrophobicContact CG1-CE1 4.08Å; V200-F366 HydrophobicContact CG1-CG 4.46Å; V200-F366 HydrophobicContact CG2-CD1 3.9Å; V200-F366 HydrophobicContact CG2-CE1 3.57Å; L362-F366 PolarHBondContact O-N 3.32Å; H363-F366 PolarHBondContact O-N 3.45Å; S364-F366 VanDerWaalsContact C-N 3.34Å; S364-F366 PolarHBondContact O-N 3.48Å; F366-C369 PolarHBondContact O-N 2.97Å; F366-Y370 VanDerWaalsContact O-CB 3.3Å; F366-Y370 WeakPolarHBondContact O-CB 3.42Å; F366-Y370 PolarHBondContact O-N 3.48Å
367	L	95.7	Very high	92.9	Very high	4 Å²	4	31.4 Å²	31.4	2%	0.021	17%	0.173	C	C	.	.	H	α-helix	trans	-63.7	-41.8	179.1	-68.7	173.5	0	0	0	112.5	V200 H363 S364 C365 Y370 V371 L383 L384 C387	V200-L367 HydrophobicContact CG2-CD2 3.98Å; H363-L367 VanDerWaalsContact CE1-CD1 3.49Å; H363-L367 WeakPolarHBondContact CE1-CD1 3.44Å; H363-L367 WeakPolarHBondContact O-CG 3.41Å; H363-L367 PolarHBondContact O-N 3.36Å; H363-L367 VanDerWaalsContact O-N 3.15Å; S364-L367 PolarHBondContact O-N 2.92Å; C365-L367 VanDerWaalsContact C-N 3.34Å; C365-L367 PolarHBondContact O-N 2.91Å; L367-Y370 PolarHBondContact O-N 3.41Å; L367-V371 WeakPolarHBondContact O-CG2 3.4Å; L367-V371 PolarHBondContact O-N 3.38Å; L367-L383 HydrophobicContact CB-CD2 4.28Å; L367-L383 HydrophobicContact CD2-CD2 4.27Å; L367-L384 HydrophobicContact CB-CD2 3.96Å; L367-L384 HydrophobicContact CD1-CD2 4.28Å; L367-C387 HydrophobicContact CD1-CB 3.45Å; L367-C387 VanDerWaalsContact CD1-CB 3.45Å
368	V	96.1	Very high	93.1	Very high	9 Å²	9	33.3 Å²	33.3	6%	0.055	18%	0.182	C	C	.	.	H	α-helix	trans	-61.3	-50.4	176.1	169.4	0	0	0	0	110.5	F335 F338 S364 C365 Y370 V371 Y372 L380 L384	F335-V368 HydrophobicContact CD2-CG1 4.03Å; F335-V368 HydrophobicContact CE2-CG1 3.71Å; F338-V368 HydrophobicContact CD1-CB 4.49Å; F338-V368 HydrophobicContact CD1-CG1 4.28Å; F338-V368 HydrophobicContact CD1-CG2 3.73Å; F338-V368 HydrophobicContact CD2-CG2 4.12Å; F338-V368 HydrophobicContact CE1-CB 4.13Å; F338-V368 HydrophobicContact CE1-CG1 4Å; F338-V368 HydrophobicContact CE1-CG2 3.76Å; F338-V368 HydrophobicContact CE2-CG2 4.15Å; F338-V368 HydrophobicContact CG-CG2 3.91Å; F338-V368 HydrophobicContact CZ-CB 4.37Å; F338-V368 HydrophobicContact CZ-CG2 3.97Å; S364-V368 WeakPolarHBondContact O-CB 3.43Å; S364-V368 VanDerWaalsContact O-CG2 3.24Å; S364-V368 WeakPolarHBondContact O-CG2 3.46Å; S364-V368 PolarHBondContact O-N 2.97Å; C365-V368 PolarHBondContact O-N 2.86Å; V368-Y370 VanDerWaalsContact C-N 3.29Å; V368-Y370 PolarHBondContact O-N 3.08Å; V368-V371 PolarHBondContact O-N 3.26Å; V368-Y372 HydrophobicContact CG1-CD2 4.04Å; V368-Y372 HydrophobicContact CG1-CE2 4.29Å; V368-Y372 WeakPolarHBondContact O-CD2 3.38Å; V368-Y372 PolarHBondContact O-N 3.35Å; V368-L380 HydrophobicContact CG2-CD1 4.14Å; V368-L384 HydrophobicContact CG2-CD1 3.79Å; V368-L384 HydrophobicContact CG2-CD2 4.17Å
369	C	95.3	Very high	93.3	Very high	85 Å²	85	32.4 Å²	32.4	57%	0.574	17%	0.172	S	C	*	.	H	α-helix	trans	-59.3	-43.3	177.5	-69	0	0	0	0	111.3	C365 F366 A373	C365-C369 WeakPolarHBondContact O-CB 3.21Å; C365-C369 PolarHBondContact O-N 3.42Å; C365-C369 PolarHBondContact O-SG 2.85Å; F366-C369 PolarHBondContact O-N 2.97Å; C369-A373 WeakPolarHBondContact O-CB 3.31Å; C369-A373 PolarHBondContact O-N 3.44Å
370	Y	93.3	Very high	93.5	Very high	86 Å²	86	32 Å²	32	34%	0.337	17%	0.171	S	C	.	.	H	α-helix	trans	-61.9	-44.6	177.6	178.7	-109.1	0	0	0	112.1	F366 L367 V368 A373 C374 C375	F366-Y370 VanDerWaalsContact O-CB 3.3Å; F366-Y370 WeakPolarHBondContact O-CB 3.42Å; F366-Y370 PolarHBondContact O-N 3.48Å; L367-Y370 PolarHBondContact O-N 3.41Å; V368-Y370 VanDerWaalsContact C-N 3.29Å; V368-Y370 PolarHBondContact O-N 3.08Å; Y370-A373 PolarHBondContact O-N 3.45Å; Y370-C374 HydrophobicContact CD2-CB 4.06Å; Y370-C374 HydrophobicContact CE2-CB 3.79Å; Y370-C374 WeakPolarHBondContact O-CB 3.2Å; Y370-C374 PolarHBondContact O-N 3.29Å; Y370-C375 WeakPolarHBondContact CE1-SG 3.44Å
371	V	94	Very high	93.6	Very high	0 Å²	0	31.9 Å²	31.9	0%	0	17%	0.17	C	C	.	.	H	α-helix	trans	-63.2	-50.2	178.5	169.3	0	0	0	0	111.3	L367 V368 A373 C375 I379 L380 L383	L367-V371 WeakPolarHBondContact O-CG2 3.4Å; L367-V371 PolarHBondContact O-N 3.38Å; V368-V371 PolarHBondContact O-N 3.26Å; V371-A373 VanDerWaalsContact C-N 3.26Å; V371-A373 PolarHBondContact O-N 2.94Å; V371-C375 HydrophobicContact CB-CB 4.5Å; V371-C375 HydrophobicContact CG1-CB 4.4Å; V371-C375 CarbonylContact O-C 3.56Å; V371-C375 PolarHBondContact O-N 2.89Å; V371-I379 HydrophobicContact CG1-CG1 4.36Å; V371-I379 HydrophobicContact CG2-CD1 4.45Å; V371-I379 HydrophobicContact CG2-CG1 4.25Å; V371-L380 HydrophobicContact CB-CD1 4.09Å; V371-L380 HydrophobicContact CG1-CB 4.13Å; V371-L380 HydrophobicContact CG1-CD1 4.09Å; V371-L380 HydrophobicContact CG2-CD1 4.2Å; V371-L383 HydrophobicContact CG2-CD2 3.29Å
372	Y	92.2	Very high	93.6	Very high	45 Å²	45	32.2 Å²	32.2	18%	0.176	17%	0.169	C	C	.	.	H	α-helix	trans	-68.7	-25.2	-178.8	-86.1	-93.7	0	0	0	113.3	Y320 F328 F335 V368 V377 L380	Y320-Y372 VanDerWaalsContact CE2-O 3.26Å; Y320-Y372 WeakPolarHBondContact CE2-O 3.34Å; Y320-Y372 PolarHBondContact OH-O 2.95Å; F328-Y372 HydrophobicContact CD1-CE1 4.2Å; F328-Y372 HydrophobicContact CE1-CD1 4.35Å; F328-Y372 HydrophobicContact CE1-CE1 4.03Å; F335-Y372 AromaticContact CD2-CE2 3.79Å; F335-Y372 HydrophobicContact CD2-CE2 3.79Å; F335-Y372 HydrophobicContact CE2-CE2 4.05Å; F335-Y372 HydrophobicContact CG-CE2 4.34Å; V368-Y372 HydrophobicContact CG1-CD2 4.04Å; V368-Y372 HydrophobicContact CG1-CE2 4.29Å; V368-Y372 WeakPolarHBondContact O-CD2 3.38Å; V368-Y372 PolarHBondContact O-N 3.35Å; Y372-V377 HydrophobicContact CD1-CG2 4.24Å; Y372-V377 HydrophobicContact CE1-CG1 4.13Å; Y372-V377 HydrophobicContact CE1-CG2 4.4Å; Y372-V377 HydrophobicContact CE2-CG1 4.42Å; Y372-L380 HydrophobicContact CE2-CD2 3.75Å
373	A	92.3	Very high	93.7	Very high	29 Å²	29	27.9 Å²	27.9	24%	0.24	15%	0.147	C	C	.	.	H	α-helix	trans	-86.1	-40.5	178	0	0	0	0	0	112.5	L316 L317 C369 Y370 V371	L316-A373 CarbonylContact C-O 3.48Å; L316-A373 WeakPolarHBondContact CA-O 3.49Å; L316-A373 HydrophobicContact CD1-CB 4.17Å; L317-A373 PolarHBondContact N-O 3.37Å; C369-A373 WeakPolarHBondContact O-CB 3.31Å; C369-A373 PolarHBondContact O-N 3.44Å; Y370-A373 PolarHBondContact O-N 3.45Å; V371-A373 VanDerWaalsContact C-N 3.26Å; V371-A373 PolarHBondContact O-N 2.94Å
374	C	91	Very high	93.8	Very high	37 Å²	37	27.9 Å²	27.9	25%	0.25	15%	0.147	C	C	.	.	H	α-helix	trans	-130.3	-8.5	-161.2	-61.9	0	0	0	0	114.8	V314 Y370	V314-C374 WeakPolarHBondContact CB-O 3.48Å; Y370-C374 HydrophobicContact CD2-CB 4.06Å; Y370-C374 HydrophobicContact CE2-CB 3.79Å; Y370-C374 WeakPolarHBondContact O-CB 3.2Å; Y370-C374 PolarHBondContact O-N 3.29Å
375	C	90.3	Very high	93.8	Very high	9 Å²	9	27.8 Å²	27.8	6%	0.061	15%	0.146	C	C	.	.	S	Bend	trans	-124.7	170.4	-174.6	-54.6	0	0	0	0	112.9	Y370 V371 V377 I379	Y370-C375 WeakPolarHBondContact CE1-SG 3.44Å; V371-C375 HydrophobicContact CB-CB 4.5Å; V371-C375 HydrophobicContact CG1-CB 4.4Å; V371-C375 CarbonylContact O-C 3.56Å; V371-C375 PolarHBondContact O-N 2.89Å; C375-V377 PolarHBondContact O-N 3.45Å; C375-I379 HydrophobicContact CB-CD1 3.64Å; C375-I379 HydrophobicContact CB-CG1 4.5Å
376	N	90.3	Very high	93.7	Very high	17 Å²	17	26.1 Å²	26.1	9%	0.091	13%	0.134	C	C	.	.			trans	-70.4	124.1	168	-62.4	-11.5	0	0	0	109.1	W312 V314 Y319 E378 I379	W312-N376 PolarHBondContact O-OD1 2.94Å; V314-N376 WeakPolarHBondContact CG1-OD1 3.08Å; Y319-N376 HydrophobicContact CD2-CB 3.95Å; Y319-N376 WeakPolarHBondContact CD2-OD1 3.38Å; Y319-N376 HydrophobicContact CE2-CB 3.48Å; Y319-N376 VanDerWaalsContact CE2-CB 3.48Å; Y319-N376 VanDerWaalsContact CE2-OD1 3.22Å; Y319-N376 WeakPolarHBondContact CE2-OD1 3.47Å; N376-E378 HydrophobicContact CB-CG 3.96Å; N376-E378 PolarHBondContact O-N 3.27Å; N376-I379 VanDerWaalsContact O-CG1 3.29Å; N376-I379 WeakPolarHBondContact O-CG1 3.21Å; N376-I379 PolarHBondContact O-N 2.74Å
377	V	91.8	Very high	93.7	Very high	1 Å²	1	20.9 Å²	20.9	1%	0.006	11%	0.112	C	C	.	.	G	3₁₀ helix	trans	-66.1	-23.5	-169.9	173.9	0	0	0	0	113.4	Y319 F328 S331 Y372 C375 I379 L380	Y319-V377 HydrophobicContact CD1-CB 4.3Å; Y319-V377 HydrophobicContact CD1-CG2 3.9Å; Y319-V377 HydrophobicContact CE1-CB 3.88Å; Y319-V377 HydrophobicContact CE1-CG2 4Å; F328-V377 HydrophobicContact CD1-CB 4.23Å; F328-V377 HydrophobicContact CD1-CG1 3.85Å; F328-V377 HydrophobicContact CD1-CG2 4.22Å; F328-V377 HydrophobicContact CE1-CB 4.1Å; F328-V377 HydrophobicContact CE1-CG1 4.08Å; F328-V377 HydrophobicContact CE1-CG2 3.6Å; F328-V377 HydrophobicContact CG-CG1 4.39Å; F328-V377 HydrophobicContact CZ-CB 4.34Å; F328-V377 HydrophobicContact CZ-CG2 3.79Å; S331-V377 WeakPolarHBondContact CB-O 3.36Å; S331-V377 WeakPolarHBondContact OG-CG1 3.46Å; Y372-V377 HydrophobicContact CD1-CG2 4.24Å; Y372-V377 HydrophobicContact CE1-CG1 4.13Å; Y372-V377 HydrophobicContact CE1-CG2 4.4Å; Y372-V377 HydrophobicContact CE2-CG1 4.42Å; C375-V377 PolarHBondContact O-N 3.45Å; V377-I379 PolarHBondContact O-N 3.32Å; V377-I379 VanDerWaalsContact O-N 3.16Å; V377-L380 VanDerWaalsContact O-CB 3.24Å; V377-L380 WeakPolarHBondContact O-CB 3.3Å; V377-L380 PolarHBondContact O-N 3.44Å; V377-L380 VanDerWaalsContact O-N 3.1Å
378	E	90.1	Very high	93.4	Very high	44 Å²	44	20.8 Å²	20.8	21%	0.206	11%	0.111	C	C	.	.	G	3₁₀ helix	trans	-50.4	-37.4	173.3	59.7	-145.6	-159.8	0	0	113.1	Y319 C327 N376 L380 T452	Y319-E378 PolarHBondContact OH-OE2 3.02Å; C327-E378 HydrophobicContact CB-CB 4.14Å; C327-E378 PolarHBondContact SG-OE2 2.64Å; N376-E378 HydrophobicContact CB-CG 3.96Å; N376-E378 PolarHBondContact O-N 3.27Å; E378-L380 PolarHBondContact O-N 3.34Å; E378-L380 VanDerWaalsContact O-N 3.08Å; E378-T452 VanDerWaalsContact CB-OXT 3.32Å; E378-T452 WeakPolarHBondContact CB-OXT 3.39Å; E378-T452 WeakPolarHBondContact CG-OXT 3.38Å; E378-T452 WeakPolarHBondContact O-CB 3.48Å
379	I	92.9	Very high	93.3	Very high	31 Å²	31	20.3 Å²	20.3	16%	0.159	11%	0.109	C	C	.	.	G	3₁₀ helix	trans	-71	-11.1	-175.3	81.2	-175.1	0	0	0	113.5	V371 C375 N376 V377 T381 R382 L383 T452	V371-I379 HydrophobicContact CG1-CG1 4.36Å; V371-I379 HydrophobicContact CG2-CD1 4.45Å; V371-I379 HydrophobicContact CG2-CG1 4.25Å; C375-I379 HydrophobicContact CB-CD1 3.64Å; C375-I379 HydrophobicContact CB-CG1 4.5Å; N376-I379 VanDerWaalsContact O-CG1 3.29Å; N376-I379 WeakPolarHBondContact O-CG1 3.21Å; N376-I379 PolarHBondContact O-N 2.74Å; V377-I379 PolarHBondContact O-N 3.32Å; V377-I379 VanDerWaalsContact O-N 3.16Å; I379-T381 PolarHBondContact O-N 3.1Å; I379-R382 HydrophobicContact CB-CG 4.3Å; I379-R382 VanDerWaalsContact O-CG 3.24Å; I379-R382 WeakPolarHBondContact O-CG 3.24Å; I379-R382 PolarHBondContact O-N 2.92Å; I379-L383 VanDerWaalsContact O-CB 3.23Å; I379-L383 WeakPolarHBondContact O-CB 3.2Å; I379-L383 PolarHBondContact O-N 2.68Å; I379-T452 PolarHBondContact N-OXT 3.34Å
380	L	95.7	Very high	93.2	Very high	0 Å²	0	16.6 Å²	16.6	0%	0	8%	0.083	C	C	.	.	H	α-helix	trans	-55.3	-41.8	-174	-175.3	67.7	0	0	0	112.2	T334 F335 V368 V371 Y372 V377 E378 L383 L384	T334-L380 HydrophobicContact CG2-CG 4.39Å; F335-L380 HydrophobicContact CB-CD2 4Å; F335-L380 HydrophobicContact CD2-CD2 4.46Å; V368-L380 HydrophobicContact CG2-CD1 4.14Å; V371-L380 HydrophobicContact CB-CD1 4.09Å; V371-L380 HydrophobicContact CG1-CB 4.13Å; V371-L380 HydrophobicContact CG1-CD1 4.09Å; V371-L380 HydrophobicContact CG2-CD1 4.2Å; Y372-L380 HydrophobicContact CE2-CD2 3.75Å; V377-L380 VanDerWaalsContact O-CB 3.24Å; V377-L380 WeakPolarHBondContact O-CB 3.3Å; V377-L380 PolarHBondContact O-N 3.44Å; V377-L380 VanDerWaalsContact O-N 3.1Å; E378-L380 PolarHBondContact O-N 3.34Å; E378-L380 VanDerWaalsContact O-N 3.08Å; L380-L383 PolarHBondContact O-N 2.89Å; L380-L384 HydrophobicContact CD1-CD1 3.75Å; L380-L384 HydrophobicContact CD1-CG 3.97Å; L380-L384 HydrophobicContact CG-CD1 4.02Å; L380-L384 HydrophobicContact CG-CG 4.43Å; L380-L384 PolarHBondContact O-N 2.89Å
381	T	95.5	Very high	93.3	Very high	0 Å²	0	12.7 Å²	12.7	0%	0	7%	0.068	C	C	.	.	H	α-helix	trans	-61.5	-58.3	179.9	-57.7	0	0	0	0	110.5	P150 T334 I379 L383 F385 Y437 T452	P150-T381 HydrophobicContact CB-CG2 3.64Å; T334-T381 PolarHBondContact OG1-OG1 3.04Å; I379-T381 PolarHBondContact O-N 3.1Å; T381-L383 VanDerWaalsContact C-N 3.26Å; T381-L383 PolarHBondContact O-N 3.49Å; T381-F385 HydrophobicContact CG2-CD2 4.1Å; T381-F385 HydrophobicContact CG2-CE2 4.29Å; T381-F385 VanDerWaalsContact O-CD2 3.31Å; T381-F385 WeakPolarHBondContact O-CD2 3.26Å; T381-F385 PolarHBondContact O-N 3.03Å; T381-Y437 HydrophobicContact CG2-CD1 4.39Å; T381-T452 HydrophobicContact CG2-CG2 4.37Å
382	R	94.7	Very high	93.4	Very high	34 Å²	34	12.7 Å²	12.7	13%	0.128	7%	0.068	C	C	.	.	H	α-helix	trans	-62.4	-34	179.9	65.1	177.7	-179.4	163.1	-2.9	112.6	D72 F154 E161 I379 S386	D72-R382 IonicContact OD2-CZ 3.88Å; D72-R382 IonicContact OD2-NH1 3.16Å; D72-R382 PolarHBondContact OD2-NH1 3.47Å; D72-R382 IonicContact OD2-NH2 2.69Å; F154-R382 HydrophobicContact CD2-CB 3.53Å; F154-R382 HydrophobicContact CE2-CB 3.81Å; F154-R382 HydrophobicContact CG-CB 3.99Å; F154-R382 HydrophobicContact CZ-CB 4.46Å; E161-R382 IonicContact OE1-NH1 3.32Å; I379-R382 HydrophobicContact CB-CG 4.3Å; I379-R382 VanDerWaalsContact O-CG 3.24Å; I379-R382 WeakPolarHBondContact O-CG 3.24Å; I379-R382 PolarHBondContact O-N 2.92Å; R382-S386 WeakPolarHBondContact O-CB 3.2Å; R382-S386 PolarHBondContact O-N 2.9Å; R382-S386 PolarHBondContact O-OG 3.42Å
383	L	95.5	Very high	93.4	Very high	6 Å²	6	10.8 Å²	10.8	3%	0.031	6%	0.06	C	C	.	.	H	α-helix	trans	-67.8	-55.8	179.7	-174	71.2	0	0	0	111.8	N197 L367 V371 I379 L380 T381 F385 S386 C387	N197-L383 HydrophobicContact CB-CD1 4.2Å; N197-L383 WeakPolarHBondContact ND2-CD1 3.41Å; L367-L383 HydrophobicContact CB-CD2 4.28Å; L367-L383 HydrophobicContact CD2-CD2 4.27Å; V371-L383 HydrophobicContact CG2-CD2 3.29Å; I379-L383 VanDerWaalsContact O-CB 3.23Å; I379-L383 WeakPolarHBondContact O-CB 3.2Å; I379-L383 PolarHBondContact O-N 2.68Å; L380-L383 PolarHBondContact O-N 2.89Å; T381-L383 VanDerWaalsContact C-N 3.26Å; T381-L383 PolarHBondContact O-N 3.49Å; L383-F385 PolarHBondContact O-N 3.46Å; L383-S386 PolarHBondContact O-N 3.2Å; L383-S386 PolarHBondContact O-OG 2.96Å; L383-S386 VanDerWaalsContact O-OG 3.08Å; L383-C387 WeakPolarHBondContact CD1-SG 3.45Å; L383-C387 VanDerWaalsContact O-CB 3.25Å; L383-C387 WeakPolarHBondContact O-CB 3.23Å; L383-C387 PolarHBondContact O-N 3Å; L383-C387 PolarHBondContact O-SG 3.2Å
384	L	96.1	Very high	93.5	Very high	1 Å²	1	9.7 Å²	9.7	1%	0.005	5%	0.05	C	C	.	.	H	α-helix	trans	-68.1	-36.9	-173	-69.9	-179.2	0	0	0	112.9	T334 F338 L367 V368 L380 S386 S388 L391	T334-L384 HydrophobicContact CG2-CB 4.39Å; T334-L384 HydrophobicContact CG2-CD1 3.93Å; F338-L384 HydrophobicContact CB-CD1 4.41Å; L367-L384 HydrophobicContact CB-CD2 3.96Å; L367-L384 HydrophobicContact CD1-CD2 4.28Å; V368-L384 HydrophobicContact CG2-CD1 3.79Å; V368-L384 HydrophobicContact CG2-CD2 4.17Å; L380-L384 HydrophobicContact CD1-CD1 3.75Å; L380-L384 HydrophobicContact CD1-CG 3.97Å; L380-L384 HydrophobicContact CG-CD1 4.02Å; L380-L384 HydrophobicContact CG-CG 4.43Å; L380-L384 PolarHBondContact O-N 2.89Å; L384-S386 VanDerWaalsContact C-N 3.28Å; L384-S386 PolarHBondContact O-N 3.46Å; L384-S388 PolarHBondContact O-N 3.01Å; L384-L391 HydrophobicContact CB-CD1 3.4Å; L384-L391 VanDerWaalsContact CB-CD1 3.4Å; L384-L391 HydrophobicContact CB-CG 4.39Å; L384-L391 HydrophobicContact CD1-CD1 4.08Å; L384-L391 HydrophobicContact CG-CD1 4.4Å
385	F	95.6	Very high	93.7	Very high	0 Å²	0	8 Å²	8	0%	0	4%	0.038	C	C	.	.	H	α-helix	trans	-71.1	-20.1	178.4	-81.7	-71.7	0	0	0	113.9	P150 A151 Y169 T334 L337 T381 L383 L391 Y392 W433 F434	P150-F385 HydrophobicContact CB-CD2 4.37Å; P150-F385 HydrophobicContact CB-CE2 3.96Å; P150-F385 HydrophobicContact CG-CD2 4.39Å; P150-F385 HydrophobicContact CG-CE2 3.62Å; P150-F385 HydrophobicContact CG-CZ 3.71Å; A151-F385 HydrophobicContact CB-CB 3.84Å; A151-F385 HydrophobicContact CB-CG 4.5Å; Y169-F385 PolarHBondContact OH-O 2.94Å; T334-F385 HydrophobicContact CG2-CE2 4.24Å; L337-F385 HydrophobicContact CD2-CZ 4.39Å; T381-F385 HydrophobicContact CG2-CD2 4.1Å; T381-F385 HydrophobicContact CG2-CE2 4.29Å; T381-F385 VanDerWaalsContact O-CD2 3.31Å; T381-F385 WeakPolarHBondContact O-CD2 3.26Å; T381-F385 PolarHBondContact O-N 3.03Å; L383-F385 PolarHBondContact O-N 3.46Å; F385-L391 HydrophobicContact CD1-CB 4.11Å; F385-L391 HydrophobicContact CD1-CD1 4.35Å; F385-L391 HydrophobicContact CD2-CD1 4.08Å; F385-L391 HydrophobicContact CE1-CB 3.78Å; F385-L391 HydrophobicContact CE1-CD1 4.28Å; F385-L391 HydrophobicContact CE2-CD1 3.97Å; F385-L391 HydrophobicContact CG-CD1 4.28Å; F385-L391 HydrophobicContact CZ-CB 4.17Å; F385-L391 HydrophobicContact CZ-CD1 4.09Å; F385-Y392 HydrophobicContact CD1-CD1 4.03Å; F385-Y392 AromaticContact CD1-CE1 3.44Å; F385-Y392 HydrophobicContact CD1-CE1 3.44Å; F385-Y392 VanDerWaalsContact CD1-CE1 3.44Å; F385-Y392 HydrophobicContact CD1-CE2 4.09Å; F385-Y392 AromaticContact CD1-CZ 3.49Å; F385-Y392 VanDerWaalsContact CD1-CZ 3.49Å; F385-Y392 HydrophobicContact CE1-CD1 4.03Å; F385-Y392 AromaticContact CE1-CE1 3.75Å; F385-Y392 HydrophobicContact CE1-CE1 3.75Å; F385-Y392 WeakPolarHBondContact O-CE2 3.46Å; F385-Y392 PolarHBondContact O-OH 3.34Å; F385-W433 AromaticContact CE2-CH2 3.7Å; F385-W433 HydrophobicContact CE2-CH2 3.7Å; F385-W433 HydrophobicContact CE2-CZ2 4.19Å; F385-W433 AromaticContact CZ-CH2 3.69Å; F385-W433 HydrophobicContact CZ-CH2 3.69Å; F385-W433 HydrophobicContact CZ-CZ3 4.24Å; F385-F434 HydrophobicContact CE1-CE1 4.14Å; F385-F434 AromaticContact CE1-CZ 3.79Å; F385-F434 HydrophobicContact CE1-CZ 3.79Å; F385-F434 HydrophobicContact CZ-CE1 4.39Å; F385-F434 HydrophobicContact CZ-CE2 4.28Å; F385-F434 AromaticContact CZ-CZ 3.79Å; F385-F434 HydrophobicContact CZ-CZ 3.79Å
386	S	94.5	Very high	93.8	Very high	0 Å²	0	7.5 Å²	7.5	0%	0	4%	0.035	C	C	.	.	H	α-helix	trans	-97	-31.8	175.7	61.6	0	0	0	0	113.2	A165 R382 L383 L384	A165-S386 WeakPolarHBondContact CA-O 3.24Å; A165-S386 VanDerWaalsContact CB-O 3.28Å; A165-S386 WeakPolarHBondContact CB-O 3.33Å; R382-S386 WeakPolarHBondContact O-CB 3.2Å; R382-S386 PolarHBondContact O-N 2.9Å; R382-S386 PolarHBondContact O-OG 3.42Å; L383-S386 PolarHBondContact O-N 3.2Å; L383-S386 PolarHBondContact O-OG 2.96Å; L383-S386 VanDerWaalsContact O-OG 3.08Å; L384-S386 VanDerWaalsContact C-N 3.28Å; L384-S386 PolarHBondContact O-N 3.46Å
387	C	94.1	Very high	93.8	Very high	1 Å²	1	8.6 Å²	8.6	1%	0.007	4%	0.04	C	C	.	.	H	α-helix	trans	-80.8	-27.7	-177	-70.9	0	0	0	0	114.6	F164 L367 L383	F164-C387 HydrophobicContact CE1-CB 4.03Å; F164-C387 WeakPolarHBondContact CE1-SG 3.37Å; F164-C387 HydrophobicContact CZ-CB 4.2Å; F164-C387 WeakPolarHBondContact CZ-SG 3.4Å; L367-C387 HydrophobicContact CD1-CB 3.45Å; L367-C387 VanDerWaalsContact CD1-CB 3.45Å; L383-C387 WeakPolarHBondContact CD1-SG 3.45Å; L383-C387 VanDerWaalsContact O-CB 3.25Å; L383-C387 WeakPolarHBondContact O-CB 3.23Å; L383-C387 PolarHBondContact O-N 3Å; L383-C387 PolarHBondContact O-SG 3.2Å
388	S	90.1	Very high	93.8	Very high	1 Å²	1	11 Å²	11	1%	0.007	5%	0.052	C	C	.	.			trans	-149.2	137	-169.3	-179.8	0	0	0	0	111.8	Y169 S364 L384 L390	Y169-S388 VanDerWaalsContact OH-C 3.25Å; Y169-S388 PolarHBondContact OH-O 3.05Å; S364-S388 PolarHBondContact OG-OG 2.95Å; L384-S388 PolarHBondContact O-N 3.01Å; S388-L390 PolarHBondContact O-N 3.42Å; S388-L390 VanDerWaalsContact OG-CB 3.27Å; S388-L390 WeakPolarHBondContact OG-CB 3.26Å; S388-L390 PolarHBondContact OG-N 3.48Å
389	P	93.5	Very high	93.8	Very high	0 Å²	0	8.9 Å²	8.9	0%	0	4%	0.043	C	C	.	.	T	Hydrogen-bonded Turn	trans	-78.1	1.5	174.7	36.8	-38.2	0	0	0	113	L125 V128 M129 Y169 M172 L360 L391 Y392 W393	L125-P389 HydrophobicContact CD1-CB 3.53Å; V128-P389 HydrophobicContact CG1-CG 4.21Å; M129-P389 HydrophobicContact CE-CB 3.34Å; M129-P389 HydrophobicContact CE-CG 3.52Å; M129-P389 HydrophobicContact SD-CB 4.29Å; Y169-P389 HydrophobicContact CE1-CB 4.3Å; Y169-P389 HydrophobicContact CE1-CG 4.34Å; M172-P389 HydrophobicContact SD-CG 4.48Å; L360-P389 HydrophobicContact CD1-CG 4.23Å; L360-P389 HydrophobicContact CD2-CG 4.4Å; P389-L391 VanDerWaalsContact C-N 3.34Å; P389-L391 PolarHBondContact O-N 3.35Å; P389-Y392 PolarHBondContact O-N 3.4Å; P389-W393 PolarHBondContact O-N 2.73Å
390	L	94.1	Very high	93.7	Very high	6 Å²	6	8.5 Å²	8.5	3%	0.031	4%	0.039	C	C	.	.	H	α-helix	trans	-56.5	-43.9	-177.1	179.1	68.2	0	0	0	112.7	L360 L361 S364 S388 W393 Q394	L360-L390 HydrophobicContact CB-CB 4.43Å; L361-L390 HydrophobicContact CD1-CD2 3.89Å; S364-L390 WeakPolarHBondContact OG-CD2 3.1Å; S388-L390 PolarHBondContact O-N 3.42Å; S388-L390 VanDerWaalsContact OG-CB 3.27Å; S388-L390 WeakPolarHBondContact OG-CB 3.26Å; S388-L390 PolarHBondContact OG-N 3.48Å; L390-W393 PolarHBondContact O-N 2.91Å; L390-Q394 WeakPolarHBondContact O-CB 3.48Å; L390-Q394 PolarHBondContact O-N 3.22Å
391	L	95	Very high	93.2	Very high	4 Å²	4	17 Å²	17	2%	0.021	7%	0.071	C	C	.	.	H	α-helix	trans	-68.6	-38.4	-178.1	-70.9	-179.8	0	0	0	112	T334 L337 F338 L384 F385 P389 W393 Q394 A395	T334-L391 HydrophobicContact CG2-CD1 3.78Å; L337-L391 HydrophobicContact CB-CD2 4.23Å; L337-L391 HydrophobicContact CD2-CB 4.18Å; L337-L391 HydrophobicContact CD2-CD2 3.94Å; L337-L391 HydrophobicContact CG-CD2 3.89Å; F338-L391 HydrophobicContact CB-CD2 4.09Å; L384-L391 HydrophobicContact CB-CD1 3.4Å; L384-L391 VanDerWaalsContact CB-CD1 3.4Å; L384-L391 HydrophobicContact CB-CG 4.39Å; L384-L391 HydrophobicContact CD1-CD1 4.08Å; L384-L391 HydrophobicContact CG-CD1 4.4Å; F385-L391 HydrophobicContact CD1-CB 4.11Å; F385-L391 HydrophobicContact CD1-CD1 4.35Å; F385-L391 HydrophobicContact CD2-CD1 4.08Å; F385-L391 HydrophobicContact CE1-CB 3.78Å; F385-L391 HydrophobicContact CE1-CD1 4.28Å; F385-L391 HydrophobicContact CE2-CD1 3.97Å; F385-L391 HydrophobicContact CG-CD1 4.28Å; F385-L391 HydrophobicContact CZ-CB 4.17Å; F385-L391 HydrophobicContact CZ-CD1 4.09Å; P389-L391 VanDerWaalsContact C-N 3.34Å; P389-L391 PolarHBondContact O-N 3.35Å; L391-W393 VanDerWaalsContact C-N 3.34Å; L391-Q394 PolarHBondContact O-N 3.37Å; L391-A395 WeakPolarHBondContact O-CB 3.03Å; L391-A395 PolarHBondContact O-N 2.92Å
392	Y	95.3	Very high	92.6	Very high	0 Å²	0	19 Å²	19	0%	0	8%	0.082	C	C	.	.	H	α-helix	trans	-63.1	-43.8	172.7	-62.7	-58.5	0	0	0	111.2	L125 L145 H146 S149 F155 F385 P389 Q394 A396	L125-Y392 HydrophobicContact CD1-CD2 4.12Å; L125-Y392 HydrophobicContact CD2-CD2 4.09Å; L125-Y392 HydrophobicContact CD2-CE2 4.43Å; L125-Y392 HydrophobicContact CD2-CG 4.47Å; L145-Y392 HydrophobicContact CB-CD1 4.2Å; H146-Y392 VanDerWaalsContact CA-CE1 3.44Å; H146-Y392 HydrophobicContact CB-CD1 4.25Å; H146-Y392 HydrophobicContact CB-CE1 3.88Å; H146-Y392 HydrophobicContact CB-CE2 4.37Å; H146-Y392 AromaticContact ND1-CZ 3.72Å; H146-Y392 PolarHBondContact ND1-OH 3.36Å; S149-Y392 WeakPolarHBondContact CB-OH 3.3Å; S149-Y392 PolarHBondContact OG-OH 2.96Å; F155-Y392 WeakPolarHBondContact CE2-OH 3.36Å; F385-Y392 HydrophobicContact CD1-CD1 4.03Å; F385-Y392 AromaticContact CD1-CE1 3.44Å; F385-Y392 HydrophobicContact CD1-CE1 3.44Å; F385-Y392 VanDerWaalsContact CD1-CE1 3.44Å; F385-Y392 HydrophobicContact CD1-CE2 4.09Å; F385-Y392 AromaticContact CD1-CZ 3.49Å; F385-Y392 VanDerWaalsContact CD1-CZ 3.49Å; F385-Y392 HydrophobicContact CE1-CD1 4.03Å; F385-Y392 AromaticContact CE1-CE1 3.75Å; F385-Y392 HydrophobicContact CE1-CE1 3.75Å; F385-Y392 WeakPolarHBondContact O-CE2 3.46Å; F385-Y392 PolarHBondContact O-OH 3.34Å; P389-Y392 PolarHBondContact O-N 3.4Å; Y392-Q394 VanDerWaalsContact C-N 3.33Å; Y392-Q394 PolarHBondContact O-N 3.32Å; Y392-A396 WeakPolarHBondContact O-CB 3.35Å; Y392-A396 PolarHBondContact O-N 2.87Å
393	W	93.7	Very high	91.8	Very high	6 Å²	6	17.5 Å²	17.5	2%	0.023	8%	0.077	C	C	.	.	H	α-helix	trans	-60.2	-43.6	175.2	-173.2	89.7	0	0	0	111.3	M129 D133 F138 I344 F346 P389 L390 L391 A396 Q397	M129-W393 HydrophobicContact SD-CB 3.98Å; M129-W393 HydrophobicContact SD-CG 4.41Å; D133-W393 PolarHBondContact OD2-NE1 2.76Å; F138-W393 AromaticContact CE1-CD1 3.28Å; F138-W393 HydrophobicContact CE1-CG 4.08Å; F138-W393 AromaticContact CE1-NE1 3.39Å; F138-W393 AromaticContact CZ-CD1 3.56Å; F138-W393 HydrophobicContact CZ-CD2 4.3Å; F138-W393 AromaticContact CZ-CE2 3.97Å; F138-W393 HydrophobicContact CZ-CG 4Å; F138-W393 AromaticContact CZ-NE1 3.45Å; F138-W393 WeakPolarHBondContact CZ-O 3.21Å; I344-W393 HydrophobicContact CD1-CE3 4.33Å; I344-W393 HydrophobicContact CD1-CH2 4.25Å; I344-W393 HydrophobicContact CD1-CZ3 3.46Å; I344-W393 VanDerWaalsContact CD1-CZ3 3.46Å; I344-W393 HydrophobicContact CG2-CH2 4.08Å; I344-W393 HydrophobicContact CG2-CZ3 4.26Å; F346-W393 HydrophobicContact CD1-CH2 4.45Å; P389-W393 PolarHBondContact O-N 2.73Å; L390-W393 PolarHBondContact O-N 2.91Å; L391-W393 VanDerWaalsContact C-N 3.34Å; W393-A396 PolarHBondContact O-N 3.32Å; W393-Q397 HydrophobicContact CH2-CG 4.31Å; W393-Q397 WeakPolarHBondContact O-CB 3.48Å; W393-Q397 PolarHBondContact O-N 3.35Å
394	Q	93.5	Very high	90.7	Very high	6 Å²	6	23 Å²	23	3%	0.028	10%	0.102	C	C	.	.	H	α-helix	trans	-70.4	-43.9	-178.2	176.1	54.9	-3.7	0	0	113	L337 S340 L390 L391 Y392 A396 Q397 L398	L337-Q394 HydrophobicContact CD1-CB 4.48Å; L337-Q394 HydrophobicContact CD1-CG 3.79Å; L337-Q394 HydrophobicContact CG-CG 4.31Å; S340-Q394 PolarHBondContact O-NE2 3.11Å; S340-Q394 WeakPolarHBondContact OG-CG 3.42Å; S340-Q394 PolarHBondContact OG-NE2 3.25Å; L390-Q394 WeakPolarHBondContact O-CB 3.48Å; L390-Q394 PolarHBondContact O-N 3.22Å; L391-Q394 PolarHBondContact O-N 3.37Å; Y392-Q394 VanDerWaalsContact C-N 3.33Å; Y392-Q394 PolarHBondContact O-N 3.32Å; Q394-A396 VanDerWaalsContact C-N 3.31Å; Q394-A396 PolarHBondContact O-N 2.9Å; Q394-Q397 PolarHBondContact O-N 3.29Å; Q394-L398 HydrophobicContact CG-CD1 4.41Å; Q394-L398 WeakPolarHBondContact O-CG 3.35Å; Q394-L398 PolarHBondContact O-N 3.4Å
395	A	94.4	Very high	89.6	Confident	0 Å²	0	31 Å²	31	0%	0	14%	0.14	C	C	.	.	H	α-helix	trans	-60.8	-43.1	173.8	0	0	0	0	0	111	L145 L337 L391 Q397 L398 I399 I430 F434	L145-A395 HydrophobicContact CD1-CB 3.82Å; L337-A395 HydrophobicContact CD1-CB 4.4Å; L337-A395 HydrophobicContact CD2-CB 4.04Å; L391-A395 WeakPolarHBondContact O-CB 3.03Å; L391-A395 PolarHBondContact O-N 2.92Å; A395-Q397 VanDerWaalsContact C-N 3.32Å; A395-Q397 PolarHBondContact O-N 2.99Å; A395-L398 PolarHBondContact O-N 3.31Å; A395-I399 WeakPolarHBondContact O-CG1 3.32Å; A395-I399 PolarHBondContact O-N 2.88Å; A395-I399 VanDerWaalsContact O-N 3.13Å; A395-I430 HydrophobicContact CB-CG2 4.18Å; A395-F434 HydrophobicContact CB-CE2 4.04Å; A395-F434 HydrophobicContact CB-CZ 3.75Å
396	A	93	Very high	89	Confident	0 Å²	0	31.5 Å²	31.5	0%	0	14%	0.142	C	C	.	.	H	α-helix	trans	-61.8	-39.7	174.7	0	0	0	0	0	111.8	F138 L141 C142 L145 Y392 W393 Q394 I399 Y400	F138-A396 HydrophobicContact CD2-CB 4.38Å; F138-A396 HydrophobicContact CE1-CB 4.18Å; F138-A396 HydrophobicContact CE2-CB 3.77Å; F138-A396 HydrophobicContact CZ-CB 3.65Å; L141-A396 HydrophobicContact CD2-CB 3.94Å; L141-A396 HydrophobicContact CG-CB 3.97Å; C142-A396 VanDerWaalsContact SG-CB 3.53Å; L145-A396 HydrophobicContact CD1-CB 3.86Å; Y392-A396 WeakPolarHBondContact O-CB 3.35Å; Y392-A396 PolarHBondContact O-N 2.87Å; W393-A396 PolarHBondContact O-N 3.32Å; Q394-A396 VanDerWaalsContact C-N 3.31Å; Q394-A396 PolarHBondContact O-N 2.9Å; A396-I399 PolarHBondContact O-N 3.16Å; A396-Y400 WeakPolarHBondContact O-CA 3.31Å; A396-Y400 WeakPolarHBondContact O-CB 3.16Å; A396-Y400 PolarHBondContact O-N 2.97Å
397	Q	91	Very high	88.5	Confident	40 Å²	40	36.9 Å²	36.9	19%	0.187	17%	0.171	C	C	.	.	H	α-helix	trans	-64.2	-40.7	178.8	-173.1	68.5	4.8	0	0	112.6	F138 W393 Q394 A395 R401	F138-Q397 HydrophobicContact CE2-CB 4.18Å; F138-Q397 HydrophobicContact CZ-CB 4.37Å; W393-Q397 HydrophobicContact CH2-CG 4.31Å; W393-Q397 WeakPolarHBondContact O-CB 3.48Å; W393-Q397 PolarHBondContact O-N 3.35Å; Q394-Q397 PolarHBondContact O-N 3.29Å; A395-Q397 VanDerWaalsContact C-N 3.32Å; A395-Q397 PolarHBondContact O-N 2.99Å; Q397-R401 WeakPolarHBondContact O-CB 3.41Å; Q397-R401 PolarHBondContact O-N 3.09Å; Q397-R401 VanDerWaalsContact O-N 3.1Å
398	L	90.9	Very high	88.3	Confident	51 Å²	51	37.3 Å²	37.3	27%	0.267	17%	0.173	S	C	.	.	H	α-helix	trans	-65.5	-46.2	176.9	-67.5	169.7	0	0	0	111.2	L337 Q394 A395 S427 I430	L337-L398 HydrophobicContact CD1-CD1 3.91Å; Q394-L398 HydrophobicContact CG-CD1 4.41Å; Q394-L398 WeakPolarHBondContact O-CG 3.35Å; Q394-L398 PolarHBondContact O-N 3.4Å; A395-L398 PolarHBondContact O-N 3.31Å; L398-S427 PolarHBondContact O-OG 3.32Å; L398-I430 HydrophobicContact CB-CD1 3.82Å; L398-I430 HydrophobicContact CD1-CD1 3.44Å; L398-I430 VanDerWaalsContact CD1-CD1 3.44Å; L398-I430 HydrophobicContact CG-CD1 4.25Å
399	I	91.5	Very high	88.3	Confident	0 Å²	0	39.1 Å²	39.1	0%	0	19%	0.185	C	C	.	.	H	α-helix	trans	-68.4	-43.2	178.9	-64.7	168	0	0	0	111.6	L141 L145 A395 A396 R401 D402 C403 S427	L141-I399 HydrophobicContact CD1-CG2 4.44Å; L141-I399 HydrophobicContact CD2-CB 4.16Å; L141-I399 HydrophobicContact CD2-CG2 4.01Å; L145-I399 HydrophobicContact CD1-CD1 4.3Å; L145-I399 HydrophobicContact CD2-CD1 3.92Å; A395-I399 WeakPolarHBondContact O-CG1 3.32Å; A395-I399 PolarHBondContact O-N 2.88Å; A395-I399 VanDerWaalsContact O-N 3.13Å; A396-I399 PolarHBondContact O-N 3.16Å; I399-R401 VanDerWaalsContact C-N 3.32Å; I399-R401 PolarHBondContact O-N 2.81Å; I399-D402 PolarHBondContact O-N 3.24Å; I399-C403 PolarHBondContact O-N 2.94Å; I399-S427 WeakPolarHBondContact CA-OG 3.48Å
400	Y	89.5	Confident	88.2	Confident	22 Å²	22	42.8 Å²	42.8	9%	0.086	20%	0.204	C	C	.	.	H	α-helix	trans	-69.7	-29.3	-176.2	-168	-88.5	0	0	0	112.6	R135 K137 F138 L141 A396 D402 C403 H404	R135-Y400 VanDerWaalsContact NH1-CD1 3.27Å; K137-Y400 HydrophobicContact CB-CE2 4.27Å; F138-Y400 HydrophobicContact CB-CD2 4.46Å; F138-Y400 HydrophobicContact CD2-CD1 4.32Å; F138-Y400 HydrophobicContact CD2-CD2 4.25Å; F138-Y400 AromaticContact CD2-CG 3.91Å; F138-Y400 HydrophobicContact CD2-CG 3.91Å; L141-Y400 HydrophobicContact CD2-CD2 4.48Å; A396-Y400 WeakPolarHBondContact O-CA 3.31Å; A396-Y400 WeakPolarHBondContact O-CB 3.16Å; A396-Y400 PolarHBondContact O-N 2.97Å; Y400-D402 PolarHBondContact O-N 2.87Å; Y400-C403 CarbonylContact O-C 3.54Å; Y400-C403 VanDerWaalsContact O-C 3.22Å; Y400-C403 PolarHBondContact O-N 2.77Å; Y400-C403 VanDerWaalsContact O-N 3.14Å; Y400-H404 AromaticContact CE1-ND1 3.6Å; Y400-H404 PolarHBondContact O-N 3.17Å; Y400-H404 PolarHBondContact OH-O 3.42Å; Y400-H404 VanDerWaalsContact OH-O 3.08Å
401	R	85.3	Confident	88.1	Confident	179 Å²	179	45.1 Å²	45.1	68%	0.675	22%	0.217	S	C	*	.	H	α-helix	trans	-60.6	-35.4	175.2	-167.7	-177.9	84.8	168.5	7.9	111.9	Q397 I399	Q397-R401 WeakPolarHBondContact O-CB 3.41Å; Q397-R401 PolarHBondContact O-N 3.09Å; Q397-R401 VanDerWaalsContact O-N 3.1Å; I399-R401 VanDerWaalsContact C-N 3.32Å; I399-R401 PolarHBondContact O-N 2.81Å
402	D	82.2	Confident	88	Confident	43 Å²	43	45.2 Å²	45.2	23%	0.23	22%	0.217	C	C	.	.	H	α-helix	trans	-82.5	-20.8	179.2	-59.7	-18	0	0	0	111.7	I399 Y400 T424 S427	I399-D402 PolarHBondContact O-N 3.24Å; Y400-D402 PolarHBondContact O-N 2.87Å; D402-T424 HydrophobicContact CB-CG2 3.98Å; D402-T424 WeakPolarHBondContact OD2-CB 3.5Å; D402-T424 VanDerWaalsContact OD2-CG2 3.31Å; D402-T424 WeakPolarHBondContact OD2-CG2 3.22Å; D402-T424 PolarHBondContact OD2-N 3.07Å; D402-T424 PolarHBondContact OD2-OG1 2.83Å; D402-S427 WeakPolarHBondContact OD2-CB 3.48Å; D402-S427 PolarHBondContact OD2-OG 3.46Å
403	C	79.3	Confident	87.9	Confident	2 Å²	2	49.8 Å²	49.8	1%	0.014	25%	0.245	C	C	.	.			trans	-136.5	71.5	-170.6	-70.9	0	0	0	0	113.7	I399 Y400 E405 L406 C422	I399-C403 PolarHBondContact O-N 2.94Å; Y400-C403 CarbonylContact O-C 3.54Å; Y400-C403 VanDerWaalsContact O-C 3.22Å; Y400-C403 PolarHBondContact O-N 2.77Å; Y400-C403 VanDerWaalsContact O-N 3.14Å; C403-E405 PolarHBondContact O-N 3.31Å; C403-L406 HydrophobicContact CB-CB 4.27Å; C403-L406 HydrophobicContact CB-CD1 3.51Å; C403-L406 HydrophobicContact CB-CG 4.46Å; C403-L406 WeakPolarHBondContact O-CB 3.45Å; C403-L406 PolarHBondContact O-N 3.39Å; C403-C422 WeakPolarHBondContact CA-SG 3.45Å; C403-C422 HydrophobicContact CB-CB 4.16Å; C403-C422 WeakPolarHBondContact CB-SG 3.38Å; C403-C422 WeakPolarHBondContact SG-CA 3.39Å; C403-C422 WeakPolarHBondContact SG-CB 3.42Å; C403-C422 PolarHBondContact SG-O 3.06Å; C403-C422 CovalentContact SG-SG 2.01Å; C403-C422 PolarHBondContact SG-SG 3.22Å
404	H	72.7	Confident	87.9	Confident	120 Å²	120	55.6 Å²	55.6	56%	0.556	27%	0.27	S	S	*	.	T	Hydrogen-bonded Turn	trans	-62.3	-29	-179.7	-83	-81.8	0	0	0	113.9	Y400	Y400-H404 AromaticContact CE1-ND1 3.6Å; Y400-H404 PolarHBondContact O-N 3.17Å; Y400-H404 PolarHBondContact OH-O 3.42Å; Y400-H404 VanDerWaalsContact OH-O 3.08Å
405	E	72	Confident	87.9	Confident	171 Å²	171	55.3 Å²	55.3	80%	0.799	27%	0.269	S	S	*	.	T	Hydrogen-bonded Turn	trans	-93.8	17.3	-178.2	-61.9	-151.3	155.4	0	0	115	C403 N407	C403-E405 PolarHBondContact O-N 3.31Å; E405-N407 PolarHBondContact O-N 2.72Å
406	L	82.5	Confident	87.8	Confident	10 Å²	10	57.4 Å²	57.4	5%	0.052	28%	0.28	C	S	.	.			trans	-59.2	105.5	-175.8	-147.5	87.7	0	0	0	112.4	L141 C403 L408 I418 M419 C422	L141-L406 HydrophobicContact CD1-CD2 4.09Å; L141-L406 HydrophobicContact CD2-CD2 4.34Å; C403-L406 HydrophobicContact CB-CB 4.27Å; C403-L406 HydrophobicContact CB-CD1 3.51Å; C403-L406 HydrophobicContact CB-CG 4.46Å; C403-L406 WeakPolarHBondContact O-CB 3.45Å; C403-L406 PolarHBondContact O-N 3.39Å; L406-L408 HydrophobicContact CD2-CD1 3.92Å; L406-L408 HydrophobicContact CD2-CD2 3.76Å; L406-L408 HydrophobicContact CD2-CG 3.78Å; L406-L408 HydrophobicContact CG-CD2 4.24Å; L406-L408 HydrophobicContact CG-CG 4.28Å; L406-I418 HydrophobicContact CD1-CG2 4.35Å; L406-M419 HydrophobicContact CD2-CG 4.03Å; L406-C422 HydrophobicContact CD1-CB 4.36Å
407	N	85.3	Confident	87.9	Confident	112 Å²	112	61 Å²	61	60%	0.599	30%	0.303	S	S	*	.			trans	-102.8	93.8	173.3	-83.5	-22.7	0	0	0	109.4	K137 E405	K137-N407 WeakPolarHBondContact CE-OD1 3.49Å; K137-N407 PolarHBondContact NZ-OD1 3.27Å; E405-N407 PolarHBondContact O-N 2.72Å
408	L	89.6	Confident	87.9	Confident	11 Å²	11	62 Å²	62	6%	0.058	31%	0.309	C	S	.	.			trans	-76.7	135.1	-179.4	-66.4	168.3	0	0	0	111.1	R140 L141 V144 L406 C415 M419	R140-L408 PolarHBondContact NH1-O 3.08Å; R140-L408 PolarHBondContact NH2-O 2.9Å; L141-L408 HydrophobicContact CB-CD1 4.02Å; L141-L408 HydrophobicContact CD1-CD1 4.09Å; V144-L408 HydrophobicContact CG2-CD1 4.05Å; L406-L408 HydrophobicContact CD2-CD1 3.92Å; L406-L408 HydrophobicContact CD2-CD2 3.76Å; L406-L408 HydrophobicContact CD2-CG 3.78Å; L406-L408 HydrophobicContact CG-CD2 4.24Å; L406-L408 HydrophobicContact CG-CG 4.28Å; L408-C415 HydrophobicContact CD2-CB 3.87Å; L408-M419 HydrophobicContact CD2-CG 4.01Å
409	P	90.8	Very high	87.9	Confident	39 Å²	39	59.5 Å²	59.5	25%	0.253	30%	0.296	S	S	.	.			trans	-80.2	168.8	174.1	31.6	-35	0	0	0	111.9	R140 N411 K414 C415 I418	R140-P409 PolarHBondContact NH2-O 2.8Å; P409-N411 PolarHBondContact O-N 3.38Å; P409-K414 HydrophobicContact CG-CB 3.66Å; P409-C415 PolarHBondContact O-SG 2.98Å; P409-C415 VanDerWaalsContact O-SG 3.42Å; P409-I418 VanDerWaalsContact CD-CD1 3.48Å; P409-I418 HydrophobicContact CG-CD1 3.85Å
410	N	90	Very high	87.9	Confident	76 Å²	76	64.9 Å²	64.9	41%	0.406	32%	0.316	S	S	.	.	S	Bend	trans	-77.7	35.8	170.3	-78.3	-17.3	0	0	0	112.4	T15 P18 Q22 R140	T15-N410 PolarHBondContact O-OD1 2.66Å; P18-N410 HydrophobicContact CB-CB 4.21Å; P18-N410 HydrophobicContact CG-CB 4.34Å; Q22-N410 PolarHBondContact NE2-O 2.85Å; R140-N410 PolarHBondContact NH2-OD1 2.82Å
411	N	92.3	Very high	87.8	Confident	55 Å²	55	67.9 Å²	67.9	29%	0.294	34%	0.34	S	S	.	.			trans	-138.6	110.7	179.6	-177.7	-54.8	0	0	0	108.8	Q22 P409 V413 K414 C415	Q22-N411 VanDerWaalsContact OE1-CA 3.28Å; P409-N411 PolarHBondContact O-N 3.38Å; N411-V413 VanDerWaalsContact C-N 3.31Å; N411-V413 PolarHBondContact O-N 2.94Å; N411-V413 PolarHBondContact OD1-N 3.44Å; N411-V413 VanDerWaalsContact OD1-N 3.14Å; N411-K414 HydrophobicContact CB-CB 4.05Å; N411-K414 HydrophobicContact CB-CD 4.09Å; N411-K414 HydrophobicContact CB-CG 4.1Å; N411-K414 PolarHBondContact O-N 3.3Å; N411-K414 VanDerWaalsContact O-N 3.12Å; N411-K414 PolarHBondContact OD1-N 2.92Å; N411-C415 PolarHBondContact O-N 2.82Å; N411-C415 PolarHBondContact O-SG 3.48Å
412	L	93.1	Very high	87.8	Confident	7 Å²	7	62.1 Å²	62.1	4%	0.037	33%	0.327	C	S	.	.	H	α-helix	trans	-60.5	-41.6	-173.6	-176.3	62.9	0	0	0	111.5	L19 Q22 V144 C147 L148 K414 C415	L19-L412 HydrophobicContact CD2-CB 4.15Å; Q22-L412 HydrophobicContact CB-CB 4.19Å; V144-L412 HydrophobicContact CG1-CD1 4.08Å; C147-L412 HydrophobicContact CB-CD1 3.7Å; C147-L412 HydrophobicContact CB-CD2 3.86Å; C147-L412 HydrophobicContact CB-CG 4.46Å; L148-L412 HydrophobicContact CD1-CD1 4.49Å; L148-L412 HydrophobicContact CD2-CD1 4.07Å; L148-L412 HydrophobicContact CD2-CD2 4.18Å; L148-L412 HydrophobicContact CD2-CG 4.17Å; L148-L412 HydrophobicContact CG-CD1 4.12Å; L412-K414 VanDerWaalsContact C-N 3.31Å; L412-K414 PolarHBondContact O-N 3.28Å; L412-C415 WeakPolarHBondContact O-CB 3.42Å; L412-C415 PolarHBondContact O-N 3.45Å; L412-C415 VanDerWaalsContact O-N 3.16Å
413	V	92.5	Very high	87.9	Confident	96 Å²	96	60.3 Å²	60.3	58%	0.582	32%	0.318	S	S	*	.	H	α-helix	trans	-64.1	-38.1	177.9	-178	0	0	0	0	110.9	N411 P417	N411-V413 VanDerWaalsContact C-N 3.31Å; N411-V413 PolarHBondContact O-N 2.94Å; N411-V413 PolarHBondContact OD1-N 3.44Å; N411-V413 VanDerWaalsContact OD1-N 3.14Å; V413-P417 WeakPolarHBondContact O-CD 3.41Å
414	K	93.8	Very high	88.4	Confident	128 Å²	128	63.3 Å²	63.3	56%	0.557	34%	0.336	S	S	*	.	H	α-helix	trans	-73.9	-24.4	175.6	-66.9	-175.4	-179.1	-175.1	0	113.3	P409 N411 L412 I416 P417 I418	P409-K414 HydrophobicContact CG-CB 3.66Å; N411-K414 HydrophobicContact CB-CB 4.05Å; N411-K414 HydrophobicContact CB-CD 4.09Å; N411-K414 HydrophobicContact CB-CG 4.1Å; N411-K414 PolarHBondContact O-N 3.3Å; N411-K414 VanDerWaalsContact O-N 3.12Å; N411-K414 PolarHBondContact OD1-N 2.92Å; L412-K414 VanDerWaalsContact C-N 3.31Å; L412-K414 PolarHBondContact O-N 3.28Å; K414-I416 VanDerWaalsContact C-N 3.3Å; K414-I416 PolarHBondContact O-N 3.02Å; K414-P417 WeakPolarHBondContact O-CD 3.48Å; K414-P417 WeakPolarHBondContact O-CG 3.27Å; K414-I418 VanDerWaalsContact O-CD1 3.3Å; K414-I418 WeakPolarHBondContact O-CD1 3.27Å; K414-I418 VanDerWaalsContact O-CG1 3.3Å; K414-I418 WeakPolarHBondContact O-CG1 3.25Å
415	C	93.5	Very high	89.2	Confident	0 Å²	0	63.6 Å²	63.6	0%	0	34%	0.341	C	S	.	.	H	α-helix	trans	-63	-37.3	174.7	-67.9	0	0	0	0	112	V144 L408 P409 N411 L412 I418 M419	V144-C415 HydrophobicContact CG1-CB 4.01Å; V144-C415 HydrophobicContact CG2-CB 4.45Å; L408-C415 HydrophobicContact CD2-CB 3.87Å; P409-C415 PolarHBondContact O-SG 2.98Å; P409-C415 VanDerWaalsContact O-SG 3.42Å; N411-C415 PolarHBondContact O-N 2.82Å; N411-C415 PolarHBondContact O-SG 3.48Å; L412-C415 WeakPolarHBondContact O-CB 3.42Å; L412-C415 PolarHBondContact O-N 3.45Å; L412-C415 VanDerWaalsContact O-N 3.16Å; C415-I418 PolarHBondContact O-N 3.03Å; C415-M419 HydrophobicContact CB-CE 4.31Å; C415-M419 WeakPolarHBondContact O-CG 3.29Å; C415-M419 PolarHBondContact O-N 2.69Å
416	I	93.6	Very high	90	Very high	44 Å²	44	59.3 Å²	59.3	23%	0.226	33%	0.33	C	S	.	.	H	α-helix	trans	-58.8	-56.9	-177.1	-61.9	167	0	0	0	112.7	L148 K414 I418 M419 W420 L435	L148-I416 HydrophobicContact CD1-CD1 4.5Å; L148-I416 HydrophobicContact CD1-CG1 4Å; L148-I416 HydrophobicContact CD2-CD1 4.41Å; K414-I416 VanDerWaalsContact C-N 3.3Å; K414-I416 PolarHBondContact O-N 3.02Å; I416-I418 VanDerWaalsContact C-N 3.27Å; I416-I418 PolarHBondContact O-N 2.82Å; I416-M419 PolarHBondContact O-N 3.44Å; I416-W420 WeakPolarHBondContact O-CB 3.3Å; I416-W420 PolarHBondContact O-N 3.5Å; I416-L435 HydrophobicContact CD1-CD2 3.7Å; I416-L435 HydrophobicContact CG1-CD2 4.22Å; I416-L435 HydrophobicContact CG2-CD1 3.81Å
417	P	93.4	Very high	90.4	Very high	75 Å²	75	59 Å²	59	49%	0.487	33%	0.328	S	S	.	.	H	α-helix	trans	-65.3	-30.6	-179.4	25.4	-34.5	0	0	0	112.6	V413 K414 W420 S421	V413-P417 WeakPolarHBondContact O-CD 3.41Å; K414-P417 WeakPolarHBondContact O-CD 3.48Å; K414-P417 WeakPolarHBondContact O-CG 3.27Å; P417-W420 PolarHBondContact O-N 2.98Å; P417-S421 WeakPolarHBondContact O-CB 2.98Å; P417-S421 PolarHBondContact O-N 3.18Å; P417-S421 PolarHBondContact O-OG 3.31Å
418	I	91.1	Very high	90.8	Very high	60 Å²	60	57.7 Å²	57.7	31%	0.308	32%	0.315	S	S	.	.	H	α-helix	trans	-66.9	-44.3	175.8	-67.2	169.4	0	0	0	110.9	L406 P409 K414 C415 I416 W420 S421	L406-I418 HydrophobicContact CD1-CG2 4.35Å; P409-I418 VanDerWaalsContact CD-CD1 3.48Å; P409-I418 HydrophobicContact CG-CD1 3.85Å; K414-I418 VanDerWaalsContact O-CD1 3.3Å; K414-I418 WeakPolarHBondContact O-CD1 3.27Å; K414-I418 VanDerWaalsContact O-CG1 3.3Å; K414-I418 WeakPolarHBondContact O-CG1 3.25Å; C415-I418 PolarHBondContact O-N 3.03Å; I416-I418 VanDerWaalsContact C-N 3.27Å; I416-I418 PolarHBondContact O-N 2.82Å; I418-W420 VanDerWaalsContact C-N 3.34Å; I418-S421 PolarHBondContact O-OG 3.42Å
419	M	91.3	Very high	91	Very high	0 Å²	0	62.3 Å²	62.3	0%	0	34%	0.34	C	S	.	.	H	α-helix	trans	-63.4	-43.9	173.6	-70.4	-176.5	-62.6	0	0	110.4	L141 V144 L148 L406 L408 C415 I416 S423 L431	L141-M419 HydrophobicContact CD1-CG 4.38Å; L141-M419 HydrophobicContact CD1-SD 3.49Å; L141-M419 WeakPolarHBondContact CD1-SD 3.3Å; V144-M419 HydrophobicContact CG1-CE 3.72Å; V144-M419 HydrophobicContact CG1-SD 4.06Å; L148-M419 HydrophobicContact CD1-CE 4Å; L406-M419 HydrophobicContact CD2-CG 4.03Å; L408-M419 HydrophobicContact CD2-CG 4.01Å; C415-M419 HydrophobicContact CB-CE 4.31Å; C415-M419 WeakPolarHBondContact O-CG 3.29Å; C415-M419 PolarHBondContact O-N 2.69Å; I416-M419 PolarHBondContact O-N 3.44Å; M419-S423 WeakPolarHBondContact O-CB 3.2Å; M419-S423 PolarHBondContact O-N 2.77Å; M419-S423 VanDerWaalsContact O-N 3.11Å; M419-S423 PolarHBondContact O-OG 3.29Å; M419-L431 HydrophobicContact CB-CD2 3.75Å; M419-L431 HydrophobicContact CE-CD1 3.68Å; M419-L431 HydrophobicContact CE-CD2 4.31Å
420	W	91.6	Very high	91.2	Very high	112 Å²	112	61.6 Å²	61.6	42%	0.424	33%	0.333	S	S	.	.	H	α-helix	trans	-62.8	-46.4	-177.3	-172.6	-89.9	0	0	0	113.5	I416 P417 I418 C422 S423 R428 L431 C432	I416-W420 WeakPolarHBondContact O-CB 3.3Å; I416-W420 PolarHBondContact O-N 3.5Å; P417-W420 PolarHBondContact O-N 2.98Å; I418-W420 VanDerWaalsContact C-N 3.34Å; W420-C422 VanDerWaalsContact C-N 3.31Å; W420-C422 PolarHBondContact O-N 3.19Å; W420-S423 PolarHBondContact O-N 2.86Å; W420-R428 HydrophobicContact CD2-CG 4Å; W420-R428 HydrophobicContact CE3-CB 4.18Å; W420-R428 HydrophobicContact CE3-CG 4.01Å; W420-R428 HydrophobicContact CH2-CB 3.98Å; W420-R428 HydrophobicContact CH2-CG 4.33Å; W420-R428 HydrophobicContact CZ2-CB 4.4Å; W420-R428 HydrophobicContact CZ2-CG 4.32Å; W420-R428 HydrophobicContact CZ3-CB 3.86Å; W420-R428 HydrophobicContact CZ3-CG 4.17Å; W420-R428 PolarHBondContact O-NE 2.96Å; W420-R428 PolarHBondContact O-NH2 3.45Å; W420-L431 HydrophobicContact CB-CD2 4.38Å; W420-L431 HydrophobicContact CE3-CD2 4.14Å; W420-C432 HydrophobicContact CZ3-CB 4.34Å
421	S	88.5	Confident	91.4	Very high	85 Å²	85	58 Å²	58	59%	0.594	31%	0.314	S	S	*	.	H	α-helix	trans	-64.2	-37.5	-175.1	61.6	0	0	0	0	112.3	P417 I418	P417-S421 WeakPolarHBondContact O-CB 2.98Å; P417-S421 PolarHBondContact O-N 3.18Å; P417-S421 PolarHBondContact O-OG 3.31Å; I418-S421 PolarHBondContact O-OG 3.42Å
422	C	83.7	Confident	91.6	Very high	59 Å²	59	57.5 Å²	57.5	40%	0.399	31%	0.314	S	S	.	.	H	α-helix	trans	-88.2	-19.6	-176.6	177.5	0	0	0	0	113	C403 L406 W420	C403-C422 WeakPolarHBondContact CA-SG 3.45Å; C403-C422 HydrophobicContact CB-CB 4.16Å; C403-C422 WeakPolarHBondContact CB-SG 3.38Å; C403-C422 WeakPolarHBondContact SG-CA 3.39Å; C403-C422 WeakPolarHBondContact SG-CB 3.42Å; C403-C422 PolarHBondContact SG-O 3.06Å; C403-C422 CovalentContact SG-SG 2.01Å; C403-C422 PolarHBondContact SG-SG 3.22Å; L406-C422 HydrophobicContact CD1-CB 4.36Å; W420-C422 VanDerWaalsContact C-N 3.31Å; W420-C422 PolarHBondContact O-N 3.19Å
423	S	84.3	Confident	91.7	Very high	5 Å²	5	58.5 Å²	58.5	4%	0.035	32%	0.318	C	S	.	.			trans	-75.2	145.3	-174.5	-73.6	0	0	0	0	114.6	M419 W420 R428	M419-S423 WeakPolarHBondContact O-CB 3.2Å; M419-S423 PolarHBondContact O-N 2.77Å; M419-S423 VanDerWaalsContact O-N 3.11Å; M419-S423 PolarHBondContact O-OG 3.29Å; W420-S423 PolarHBondContact O-N 2.86Å; S423-R428 PolarHBondContact O-NE 3.4Å; S423-R428 VanDerWaalsContact O-NE 3.13Å; S423-R428 PolarHBondContact O-NH2 3.19Å
424	T	89.9	Confident	91.9	Very high	65 Å²	65	53.9 Å²	53.9	40%	0.399	29%	0.29	S	S	.	.			trans	-69.3	173.6	163.7	69.2	0	0	0	0	111.5	D402 S426 S427 R428	D402-T424 HydrophobicContact CB-CG2 3.98Å; D402-T424 WeakPolarHBondContact OD2-CB 3.5Å; D402-T424 VanDerWaalsContact OD2-CG2 3.31Å; D402-T424 WeakPolarHBondContact OD2-CG2 3.22Å; D402-T424 PolarHBondContact OD2-N 3.07Å; D402-T424 PolarHBondContact OD2-OG1 2.83Å; T424-S426 VanDerWaalsContact C-N 3.3Å; T424-S426 PolarHBondContact O-N 3.39Å; T424-S427 PolarHBondContact O-N 2.89Å; T424-R428 WeakPolarHBondContact O-CG 3.37Å; T424-R428 PolarHBondContact O-N 3.36Å
425	L	90.9	Very high	92	Very high	126 Å²	126	49.4 Å²	49.4	66%	0.66	27%	0.272	S	S	*	.	H	α-helix	trans	-52.8	-45.7	176	-178.7	62.7	0	0	0	112.3	S427 R428 L429	L425-S427 PolarHBondContact O-N 3.22Å; L425-R428 PolarHBondContact O-N 2.68Å; L425-L429 HydrophobicContact CG-CD1 4.37Å; L425-L429 WeakPolarHBondContact O-CG 3.2Å; L425-L429 PolarHBondContact O-N 3.11Å
426	S	88.6	Confident	92.2	Very high	81 Å²	81	53.5 Å²	53.5	57%	0.566	29%	0.293	S	S	*	.	H	α-helix	trans	-61.5	-44.6	-179.9	-57.9	0	0	0	0	112.1	T424 L429 I430	T424-S426 VanDerWaalsContact C-N 3.3Å; T424-S426 PolarHBondContact O-N 3.39Å; S426-L429 PolarHBondContact O-N 2.8Å; S426-I430 WeakPolarHBondContact O-CG1 3.34Å; S426-I430 PolarHBondContact O-N 2.95Å; S426-I430 VanDerWaalsContact O-N 3.17Å
427	S	90.7	Very high	92.3	Very high	2 Å²	2	52.5 Å²	52.5	1%	0.014	29%	0.286	C	S	.	.	H	α-helix	trans	-67.9	-35.7	178	-69.6	0	0	0	0	112.2	L398 I399 D402 T424 L425 I430 L431	L398-S427 PolarHBondContact O-OG 3.32Å; I399-S427 WeakPolarHBondContact CA-OG 3.48Å; D402-S427 WeakPolarHBondContact OD2-CB 3.48Å; D402-S427 PolarHBondContact OD2-OG 3.46Å; T424-S427 PolarHBondContact O-N 2.89Å; L425-S427 PolarHBondContact O-N 3.22Å; S427-I430 PolarHBondContact O-N 3.47Å; S427-L431 PolarHBondContact O-N 2.91Å
428	R	93.6	Very high	92.4	Very high	86 Å²	86	49.4 Å²	49.4	33%	0.325	27%	0.267	S	S	.	.	H	α-helix	trans	-65.2	-38.7	172.4	-71.6	178.1	-173.8	163.1	7.8	112.4	W420 S423 T424 L425 L431 C432	W420-R428 HydrophobicContact CD2-CG 4Å; W420-R428 HydrophobicContact CE3-CB 4.18Å; W420-R428 HydrophobicContact CE3-CG 4.01Å; W420-R428 HydrophobicContact CH2-CB 3.98Å; W420-R428 HydrophobicContact CH2-CG 4.33Å; W420-R428 HydrophobicContact CZ2-CB 4.4Å; W420-R428 HydrophobicContact CZ2-CG 4.32Å; W420-R428 HydrophobicContact CZ3-CB 3.86Å; W420-R428 HydrophobicContact CZ3-CG 4.17Å; W420-R428 PolarHBondContact O-NE 2.96Å; W420-R428 PolarHBondContact O-NH2 3.45Å; S423-R428 PolarHBondContact O-NE 3.4Å; S423-R428 VanDerWaalsContact O-NE 3.13Å; S423-R428 PolarHBondContact O-NH2 3.19Å; T424-R428 WeakPolarHBondContact O-CG 3.37Å; T424-R428 PolarHBondContact O-N 3.36Å; L425-R428 PolarHBondContact O-N 2.68Å; R428-L431 PolarHBondContact O-N 3.13Å; R428-C432 WeakPolarHBondContact O-CB 3.41Å; R428-C432 PolarHBondContact O-N 3.29Å
429	L	94.1	Very high	92.7	Very high	108 Å²	108	50 Å²	50	57%	0.565	27%	0.27	S	S	*	.	H	α-helix	trans	-62.9	-42.1	175.5	-71.8	172.1	0	0	0	111.7	L425 S426 C432 W433	L425-L429 HydrophobicContact CG-CD1 4.37Å; L425-L429 WeakPolarHBondContact O-CG 3.2Å; L425-L429 PolarHBondContact O-N 3.11Å; S426-L429 PolarHBondContact O-N 2.8Å; L429-C432 PolarHBondContact O-N 3.39Å; L429-W433 WeakPolarHBondContact O-CB 3.47Å; L429-W433 PolarHBondContact O-N 2.89Å
430	I	94.2	Very high	92.9	Very high	24 Å²	24	52.7 Å²	52.7	12%	0.123	29%	0.286	C	S	.	.	H	α-helix	trans	-63.1	-48.4	175.5	-64.4	168.9	0	0	0	110.4	A395 L398 S426 S427 C432 W433 F434	A395-I430 HydrophobicContact CB-CG2 4.18Å; L398-I430 HydrophobicContact CB-CD1 3.82Å; L398-I430 HydrophobicContact CD1-CD1 3.44Å; L398-I430 VanDerWaalsContact CD1-CD1 3.44Å; L398-I430 HydrophobicContact CG-CD1 4.25Å; S426-I430 WeakPolarHBondContact O-CG1 3.34Å; S426-I430 PolarHBondContact O-N 2.95Å; S426-I430 VanDerWaalsContact O-N 3.17Å; S427-I430 PolarHBondContact O-N 3.47Å; I430-C432 VanDerWaalsContact C-N 3.32Å; I430-C432 PolarHBondContact O-N 2.94Å; I430-W433 PolarHBondContact O-N 3.37Å; I430-F434 HydrophobicContact CG2-CD2 3.89Å; I430-F434 HydrophobicContact CG2-CE2 3.76Å; I430-F434 VanDerWaalsContact O-CD2 3.28Å; I430-F434 WeakPolarHBondContact O-CD2 2.77Å; I430-F434 PolarHBondContact O-N 1.98Å
431	L	94.7	Very high	93.1	Very high	0 Å²	0	47.4 Å²	47.4	0%	0	27%	0.266	C	S	.	.	H	α-helix	trans	-62.2	-41.3	179.4	-178	59.3	0	0	0	111.8	L148 M419 W420 S427 R428 F434 L435	L148-L431 HydrophobicContact CD1-CD1 4.32Å; M419-L431 HydrophobicContact CB-CD2 3.75Å; M419-L431 HydrophobicContact CE-CD1 3.68Å; M419-L431 HydrophobicContact CE-CD2 4.31Å; W420-L431 HydrophobicContact CB-CD2 4.38Å; W420-L431 HydrophobicContact CE3-CD2 4.14Å; S427-L431 PolarHBondContact O-N 2.91Å; R428-L431 PolarHBondContact O-N 3.13Å; L431-F434 PolarHBondContact O-N 3.36Å; L431-L435 HydrophobicContact CD1-CD1 4.29Å; L431-L435 HydrophobicContact CD1-CG 4.37Å; L431-L435 HydrophobicContact CG-CD1 4.12Å; L431-L435 VanDerWaalsContact O-CG 3.3Å; L431-L435 WeakPolarHBondContact O-CG 3.43Å; L431-L435 PolarHBondContact O-N 3.42Å
432	C	95.7	Very high	93.4	Very high	45 Å²	45	43.4 Å²	43.4	30%	0.304	24%	0.238	S	C	.	.	H	α-helix	trans	-60.7	-45.6	175.3	-172.1	0	0	0	0	111.1	W420 R428 L429 I430 L435 I436	W420-C432 HydrophobicContact CZ3-CB 4.34Å; R428-C432 WeakPolarHBondContact O-CB 3.41Å; R428-C432 PolarHBondContact O-N 3.29Å; L429-C432 PolarHBondContact O-N 3.39Å; I430-C432 VanDerWaalsContact C-N 3.32Å; I430-C432 PolarHBondContact O-N 2.94Å; C432-L435 PolarHBondContact O-N 2.81Å; C432-I436 WeakPolarHBondContact O-CB 3.09Å; C432-I436 VanDerWaalsContact O-CG1 3.27Å; C432-I436 WeakPolarHBondContact O-CG1 3.22Å; C432-I436 PolarHBondContact O-N 3.46Å; C432-I436 VanDerWaalsContact SG-CD1 3.52Å
433	W	96	Very high	94.1	Very high	27 Å²	27	41.1 Å²	41.1	10%	0.102	22%	0.223	C	C	.	.	H	α-helix	trans	-59.5	-47.9	175.7	166.7	54.9	0	0	0	112.6	P150 P333 T334 L337 F385 L429 I430 L435 I436 Y437	P150-W433 HydrophobicContact CB-CZ2 3.91Å; P150-W433 HydrophobicContact CG-CD2 4.33Å; P150-W433 HydrophobicContact CG-CE3 4.49Å; P150-W433 HydrophobicContact CG-CH2 3.72Å; P150-W433 HydrophobicContact CG-CZ2 3.46Å; P150-W433 VanDerWaalsContact CG-CZ2 3.46Å; P150-W433 HydrophobicContact CG-CZ3 4.22Å; P333-W433 HydrophobicContact CB-CD2 3.71Å; P333-W433 HydrophobicContact CB-CE3 4.38Å; P333-W433 HydrophobicContact CB-CG 3.95Å; P333-W433 HydrophobicContact CB-CH2 4.4Å; P333-W433 HydrophobicContact CB-CZ2 3.76Å; T334-W433 WeakPolarHBondContact OG1-CZ2 3.41Å; L337-W433 HydrophobicContact CB-CZ3 4.4Å; L337-W433 HydrophobicContact CD2-CH2 4.33Å; L337-W433 HydrophobicContact CD2-CZ3 3.85Å; F385-W433 AromaticContact CE2-CH2 3.7Å; F385-W433 HydrophobicContact CE2-CH2 3.7Å; F385-W433 HydrophobicContact CE2-CZ2 4.19Å; F385-W433 AromaticContact CZ-CH2 3.69Å; F385-W433 HydrophobicContact CZ-CH2 3.69Å; F385-W433 HydrophobicContact CZ-CZ3 4.24Å; L429-W433 WeakPolarHBondContact O-CB 3.47Å; L429-W433 PolarHBondContact O-N 2.89Å; I430-W433 PolarHBondContact O-N 3.37Å; W433-L435 PolarHBondContact O-N 3.34Å; W433-I436 PolarHBondContact O-N 3.5Å; W433-Y437 AromaticContact CD1-CD2 3.24Å; W433-Y437 AromaticContact CD1-CE2 3.28Å; W433-Y437 AromaticContact CD1-CG 3.89Å; W433-Y437 AromaticContact CD1-CZ 3.92Å; W433-Y437 HydrophobicContact CG-CD2 4.43Å; W433-Y437 AromaticContact NE1-CD1 3.65Å; W433-Y437 AromaticContact NE1-CD2 3.24Å; W433-Y437 AromaticContact NE1-CE1 3.61Å; W433-Y437 AromaticContact NE1-CE2 3.21Å; W433-Y437 AromaticContact NE1-CG 3.46Å; W433-Y437 AromaticContact NE1-CZ 3.39Å; W433-Y437 WeakPolarHBondContact O-CB 3.33Å; W433-Y437 PolarHBondContact O-N 2.8Å
434	F	96.8	Very high	94.6	Very high	0 Å²	0	43.1 Å²	43.1	0%	0	23%	0.234	C	C	.	.	H	α-helix	trans	-55.2	-49.9	176.2	-90.4	-119.6	0	0	0	111.3	L145 L148 P150 L337 F385 A395 I430 L431 Y437 A438	L145-F434 HydrophobicContact CB-CD1 4.38Å; L145-F434 HydrophobicContact CB-CE1 3.87Å; L145-F434 HydrophobicContact CD2-CD1 3.96Å; L145-F434 HydrophobicContact CD2-CE1 3.98Å; L145-F434 HydrophobicContact CG-CE1 4.46Å; L145-F434 WeakPolarHBondContact O-CE1 3.16Å; L148-F434 CarbonylContact O-C 3.38Å; L148-F434 WeakPolarHBondContact O-CB 3.26Å; L148-F434 WeakPolarHBondContact O-CD1 3.01Å; P150-F434 HydrophobicContact CG-CD1 4.4Å; P150-F434 HydrophobicContact CG-CD2 4.16Å; P150-F434 HydrophobicContact CG-CE2 4.36Å; P150-F434 HydrophobicContact CG-CG 4.2Å; L337-F434 HydrophobicContact CD2-CE2 4.41Å; F385-F434 HydrophobicContact CE1-CE1 4.14Å; F385-F434 AromaticContact CE1-CZ 3.79Å; F385-F434 HydrophobicContact CE1-CZ 3.79Å; F385-F434 HydrophobicContact CZ-CE1 4.39Å; F385-F434 HydrophobicContact CZ-CE2 4.28Å; F385-F434 AromaticContact CZ-CZ 3.79Å; F385-F434 HydrophobicContact CZ-CZ 3.79Å; A395-F434 HydrophobicContact CB-CE2 4.04Å; A395-F434 HydrophobicContact CB-CZ 3.75Å; I430-F434 HydrophobicContact CG2-CD2 3.89Å; I430-F434 HydrophobicContact CG2-CE2 3.76Å; I430-F434 VanDerWaalsContact O-CD2 3.28Å; I430-F434 WeakPolarHBondContact O-CD2 2.77Å; I430-F434 PolarHBondContact O-N 1.98Å; L431-F434 PolarHBondContact O-N 3.36Å; F434-Y437 PolarHBondContact O-N 3.09Å; F434-A438 VanDerWaalsContact O-CB 3.3Å; F434-A438 WeakPolarHBondContact O-CB 3.35Å; F434-A438 PolarHBondContact O-N 2.84Å
435	L	96.3	Very high	94.9	Very high	34 Å²	34	40.1 Å²	40.1	18%	0.178	22%	0.215	C	C	.	.	H	α-helix	trans	-65.4	-45	-179.1	-69	171.3	0	0	0	112.8	L148 I416 L431 C432 W433 A438 I439	L148-L435 HydrophobicContact CD1-CD2 4.09Å; L148-L435 HydrophobicContact CD2-CD2 3.96Å; L148-L435 HydrophobicContact CG-CD2 4.44Å; I416-L435 HydrophobicContact CD1-CD2 3.7Å; I416-L435 HydrophobicContact CG1-CD2 4.22Å; I416-L435 HydrophobicContact CG2-CD1 3.81Å; L431-L435 HydrophobicContact CD1-CD1 4.29Å; L431-L435 HydrophobicContact CD1-CG 4.37Å; L431-L435 HydrophobicContact CG-CD1 4.12Å; L431-L435 VanDerWaalsContact O-CG 3.3Å; L431-L435 WeakPolarHBondContact O-CG 3.43Å; L431-L435 PolarHBondContact O-N 3.42Å; C432-L435 PolarHBondContact O-N 2.81Å; W433-L435 PolarHBondContact O-N 3.34Å; L435-A438 PolarHBondContact O-N 2.95Å; L435-I439 WeakPolarHBondContact O-CG1 3.3Å; L435-I439 PolarHBondContact O-N 3.28Å
436	I	96.3	Very high	95.1	Very high	85 Å²	85	34.1 Å²	34.1	44%	0.436	18%	0.184	S	C	.	.	H	α-helix	trans	-60	-49.1	178	-72.4	170.6	0	0	0	109.4	C432 W433 A438 I439 V440	C432-I436 WeakPolarHBondContact O-CB 3.09Å; C432-I436 VanDerWaalsContact O-CG1 3.27Å; C432-I436 WeakPolarHBondContact O-CG1 3.22Å; C432-I436 PolarHBondContact O-N 3.46Å; C432-I436 VanDerWaalsContact SG-CD1 3.52Å; W433-I436 PolarHBondContact O-N 3.5Å; I436-A438 PolarHBondContact O-N 3.31Å; I436-I439 PolarHBondContact O-N 2.96Å; I436-V440 HydrophobicContact CG2-CG2 3.98Å; I436-V440 WeakPolarHBondContact O-CB 3.4Å; I436-V440 VanDerWaalsContact O-CG2 3.3Å; I436-V440 WeakPolarHBondContact O-CG2 3.47Å; I436-V440 PolarHBondContact O-N 3.27Å
437	Y	96.4	Very high	95.4	Very high	23 Å²	23	30.3 Å²	30.3	9%	0.09	16%	0.157	C	C	.	.	H	α-helix	trans	-67.2	-37.4	-178.5	-87.7	-126.8	0	0	0	112.3	P150 L330 T381 W433 F434 G441 W451 T452	P150-Y437 HydrophobicContact CB-CD1 3.85Å; P150-Y437 HydrophobicContact CB-CG 4.08Å; L330-Y437 HydrophobicContact CD1-CE1 4.16Å; L330-Y437 HydrophobicContact CG-CE1 4.41Å; L330-Y437 WeakPolarHBondContact O-CE1 3.27Å; L330-Y437 PolarHBondContact O-OH 3.43Å; T381-Y437 HydrophobicContact CG2-CD1 4.39Å; W433-Y437 AromaticContact CD1-CD2 3.24Å; W433-Y437 AromaticContact CD1-CE2 3.28Å; W433-Y437 AromaticContact CD1-CG 3.89Å; W433-Y437 AromaticContact CD1-CZ 3.92Å; W433-Y437 HydrophobicContact CG-CD2 4.43Å; W433-Y437 AromaticContact NE1-CD1 3.65Å; W433-Y437 AromaticContact NE1-CD2 3.24Å; W433-Y437 AromaticContact NE1-CE1 3.61Å; W433-Y437 AromaticContact NE1-CE2 3.21Å; W433-Y437 AromaticContact NE1-CG 3.46Å; W433-Y437 AromaticContact NE1-CZ 3.39Å; W433-Y437 WeakPolarHBondContact O-CB 3.33Å; W433-Y437 PolarHBondContact O-N 2.8Å; F434-Y437 PolarHBondContact O-N 3.09Å; Y437-G441 VanDerWaalsContact O-CA 3.24Å; Y437-G441 WeakPolarHBondContact O-CA 3.26Å; Y437-G441 PolarHBondContact O-N 2.96Å; Y437-W451 AromaticContact CD1-CH2 3.83Å; Y437-W451 HydrophobicContact CD1-CH2 3.83Å; Y437-W451 AromaticContact CD1-CZ2 3.49Å; Y437-W451 HydrophobicContact CD1-CZ2 3.49Å; Y437-W451 VanDerWaalsContact CD1-CZ2 3.49Å; Y437-W451 HydrophobicContact CD2-CH2 4.01Å; Y437-W451 HydrophobicContact CD2-CZ2 4.36Å; Y437-W451 HydrophobicContact CE1-CH2 4.17Å; Y437-W451 HydrophobicContact CE1-CZ2 4.14Å; Y437-W451 HydrophobicContact CE2-CH2 4.32Å; Y437-W451 AromaticContact CG-CH2 3.76Å; Y437-W451 HydrophobicContact CG-CH2 3.76Å; Y437-W451 AromaticContact CG-CZ2 3.64Å; Y437-W451 HydrophobicContact CG-CZ2 3.64Å; Y437-W451 WeakPolarHBondContact O-CZ2 3.31Å; Y437-T452 HydrophobicContact CE1-CG2 4.23Å
438	A	95.8	Very high	95.6	Very high	10 Å²	10	30.2 Å²	30.2	8%	0.083	16%	0.156	C	C	.	.	H	α-helix	trans	-63.1	-46	176.1	0	0	0	0	0	111.8	F434 L435 I436 I442	F434-A438 VanDerWaalsContact O-CB 3.3Å; F434-A438 WeakPolarHBondContact O-CB 3.35Å; F434-A438 PolarHBondContact O-N 2.84Å; L435-A438 PolarHBondContact O-N 2.95Å; I436-A438 PolarHBondContact O-N 3.31Å; A438-I442 VanDerWaalsContact O-CD1 3.29Å; A438-I442 WeakPolarHBondContact O-CD1 3.29Å; A438-I442 WeakPolarHBondContact O-CG1 3.48Å; A438-I442 PolarHBondContact O-N 3.24Å
439	I	96.7	Very high	95.6	Very high	74 Å²	74	29.6 Å²	29.6	38%	0.379	16%	0.156	S	C	.	.	H	α-helix	trans	-77.8	-53.4	-176.7	-62.3	169.1	0	0	0	111.4	L30 F34 L435 I436 G441 I442 A443	L30-I439 HydrophobicContact CD1-CG1 4.18Å; F34-I439 HydrophobicContact CE2-CG2 4.07Å; F34-I439 HydrophobicContact CZ-CG2 3.99Å; L435-I439 WeakPolarHBondContact O-CG1 3.3Å; L435-I439 PolarHBondContact O-N 3.28Å; I436-I439 PolarHBondContact O-N 2.96Å; I439-G441 VanDerWaalsContact C-N 3.29Å; I439-G441 PolarHBondContact O-N 3.31Å; I439-I442 PolarHBondContact O-N 2.95Å; I439-A443 PolarHBondContact O-N 3.11Å
440	V	96.4	Very high	95.3	Very high	56 Å²	56	28.7 Å²	28.7	34%	0.339	16%	0.156	S	C	.	.	H	α-helix	trans	-66	-36	-178.3	178.1	0	0	0	0	110.4	I436 I442 A443 L444 W451	I436-V440 HydrophobicContact CG2-CG2 3.98Å; I436-V440 WeakPolarHBondContact O-CB 3.4Å; I436-V440 VanDerWaalsContact O-CG2 3.3Å; I436-V440 WeakPolarHBondContact O-CG2 3.47Å; I436-V440 PolarHBondContact O-N 3.27Å; V440-I442 PolarHBondContact O-N 3.16Å; V440-A443 PolarHBondContact O-N 3.37Å; V440-L444 HydrophobicContact CG1-CD1 3.62Å; V440-L444 HydrophobicContact CG1-CG 3.87Å; V440-L444 WeakPolarHBondContact O-CB 3.29Å; V440-L444 WeakPolarHBondContact O-CG 3.28Å; V440-L444 PolarHBondContact O-N 3.29Å; V440-W451 HydrophobicContact CB-CH2 4.35Å; V440-W451 HydrophobicContact CB-CZ3 4.47Å; V440-W451 HydrophobicContact CG1-CH2 4.29Å; V440-W451 HydrophobicContact CG1-CZ3 3.92Å
441	G	95.5	Very high	94.9	Very high	0 Å²	0	29.1 Å²	29.1	0%	0	16%	0.157	C	C	.	.	H	α-helix	trans	-62.3	-41.1	175.9	0	0	0	0	0	113.3	Y437 I439 H445 W451	Y437-G441 VanDerWaalsContact O-CA 3.24Å; Y437-G441 WeakPolarHBondContact O-CA 3.26Å; Y437-G441 PolarHBondContact O-N 2.96Å; I439-G441 VanDerWaalsContact C-N 3.29Å; I439-G441 PolarHBondContact O-N 3.31Å; G441-H445 WeakPolarHBondContact O-CB 3.45Å; G441-H445 PolarHBondContact O-N 3.2Å; G441-W451 VanDerWaalsContact CA-NE1 3.29Å
442	I	95.8	Very high	93.8	Very high	2 Å²	2	29.5 Å²	29.5	1%	0.01	16%	0.159	C	C	.	.	H	α-helix	trans	-64.5	-47.5	172.5	-67.3	167.5	0	0	0	110.2	A27 L30 Q31 F34 T152 V153 A438 I439 V440 L444 S446	A27-I442 HydrophobicContact CB-CD1 3.98Å; L30-I442 HydrophobicContact CB-CD1 4.34Å; L30-I442 HydrophobicContact CB-CG2 4.02Å; L30-I442 HydrophobicContact CD1-CD1 4.15Å; Q31-I442 HydrophobicContact CB-CG2 3.75Å; F34-I442 HydrophobicContact CD2-CG2 4.29Å; T152-I442 HydrophobicContact CG2-CD1 4.15Å; V153-I442 HydrophobicContact CB-CG1 4.04Å; V153-I442 HydrophobicContact CG2-CG1 4.23Å; A438-I442 VanDerWaalsContact O-CD1 3.29Å; A438-I442 WeakPolarHBondContact O-CD1 3.29Å; A438-I442 WeakPolarHBondContact O-CG1 3.48Å; A438-I442 PolarHBondContact O-N 3.24Å; I439-I442 PolarHBondContact O-N 2.95Å; V440-I442 PolarHBondContact O-N 3.16Å; I442-L444 PolarHBondContact O-N 3.18Å; I442-S446 VanDerWaalsContact O-CB 3.26Å; I442-S446 WeakPolarHBondContact O-CB 3.36Å; I442-S446 PolarHBondContact O-N 3.26Å; I442-S446 PolarHBondContact O-OG 2.73Å
443	A	96.9	Very high	93.7	Very high	10 Å²	10	28.7 Å²	28.7	8%	0.083	15%	0.151	C	C	.	.	H	α-helix	trans	-58	-49.7	-178.8	0	0	0	0	0	112.8	F34 L38 I439 V440 N447	F34-A443 HydrophobicContact CB-CB 4.26Å; F34-A443 HydrophobicContact CD1-CB 3.87Å; F34-A443 VanDerWaalsContact CD2-CA 3.47Å; F34-A443 HydrophobicContact CD2-CB 3.49Å; F34-A443 VanDerWaalsContact CD2-CB 3.49Å; F34-A443 HydrophobicContact CE1-CB 4.03Å; F34-A443 HydrophobicContact CE2-CB 3.64Å; F34-A443 HydrophobicContact CG-CB 3.61Å; F34-A443 HydrophobicContact CZ-CB 3.92Å; L38-A443 HydrophobicContact CD1-CB 4.29Å; I439-A443 PolarHBondContact O-N 3.11Å; V440-A443 PolarHBondContact O-N 3.37Å; A443-N447 PolarHBondContact O-ND2 3.15Å
444	L	96	Very high	93.6	Very high	48 Å²	48	28.8 Å²	28.8	25%	0.251	15%	0.154	S	C	.	.	H	α-helix	trans	-71.7	-48.1	-176.8	-66.6	-176.5	0	0	0	111.6	V440 I442 S446 N447 F448 F449 W451	V440-L444 HydrophobicContact CG1-CD1 3.62Å; V440-L444 HydrophobicContact CG1-CG 3.87Å; V440-L444 WeakPolarHBondContact O-CB 3.29Å; V440-L444 WeakPolarHBondContact O-CG 3.28Å; V440-L444 PolarHBondContact O-N 3.29Å; I442-L444 PolarHBondContact O-N 3.18Å; L444-S446 VanDerWaalsContact C-N 3.32Å; L444-S446 PolarHBondContact O-N 3.17Å; L444-N447 CarbonylContact O-C 3.59Å; L444-N447 PolarHBondContact O-N 3.42Å; L444-N447 VanDerWaalsContact O-N 3.17Å; L444-F448 PolarHBondContact O-N 3.46Å; L444-F449 HydrophobicContact CB-CB 3.71Å; L444-F449 HydrophobicContact CD2-CB 3.64Å; L444-F449 HydrophobicContact CD2-CD1 4.44Å; L444-F449 HydrophobicContact CD2-CD2 4.24Å; L444-F449 HydrophobicContact CD2-CG 3.87Å; L444-F449 HydrophobicContact CG-CB 4.17Å; L444-F449 WeakPolarHBondContact O-CB 3.35Å; L444-F449 PolarHBondContact O-N 3.32Å; L444-W451 HydrophobicContact CB-CB 4.35Å; L444-W451 HydrophobicContact CD1-CE3 3.63Å; L444-W451 HydrophobicContact CD1-CZ3 4.02Å
445	H	95	Very high	93.4	Very high	2 Å²	2	30.4 Å²	30.4	1%	0.009	16%	0.163	C	C	.	.	H	α-helix	trans	-60.6	-42.4	-179.8	-179.1	-79.2	0	0	0	111.9	R70 W71 V153 Y159 G441 N447 F448	R70-H445 VanDerWaalsContact CB-O 3.23Å; R70-H445 WeakPolarHBondContact CB-O 3.48Å; R70-H445 WeakPolarHBondContact CG-O 3.47Å; R70-H445 PolarHBondContact O-CE1 2.65Å; W71-H445 AromaticContact CD1-CD2 3.51Å; W71-H445 AromaticContact CD1-CG 3.92Å; W71-H445 AromaticContact CD1-NE2 3.69Å; V153-H445 HydrophobicContact CG1-CB 4.41Å; V153-H445 HydrophobicContact CG2-CB 3.65Å; Y159-H445 AromaticContact CE2-CE1 3.84Å; Y159-H445 AromaticContact CE2-NE2 3.31Å; Y159-H445 VanDerWaalsContact CE2-NE2 3.31Å; Y159-H445 WeakPolarHBondContact CE2-NE2 3.27Å; Y159-H445 AromaticContact CZ-NE2 3.52Å; Y159-H445 PolarHBondContact OH-NE2 2.95Å; Y159-H445 VanDerWaalsContact OH-NE2 3.1Å; G441-H445 WeakPolarHBondContact O-CB 3.45Å; G441-H445 PolarHBondContact O-N 3.2Å; H445-N447 PolarHBondContact O-N 3.31Å; H445-N447 VanDerWaalsContact O-N 3.12Å; H445-F448 PolarHBondContact O-N 3.06Å
446	S	94.7	Very high	93.2	Very high	0 Å²	0	30.2 Å²	30.2	0%	0	16%	0.162	C	C	.	.	H	α-helix	trans	-64.8	-16.2	-178.6	-70.7	0	0	0	0	114.7	Q31 N35 G67 R70 I442 L444	Q31-S446 WeakPolarHBondContact CG-OG 3.4Å; N35-S446 PolarHBondContact OD1-O 3.2Å; G67-S446 WeakPolarHBondContact O-CA 3.43Å; G67-S446 WeakPolarHBondContact O-CB 3.42Å; G67-S446 PolarHBondContact O-OG 3.42Å; R70-S446 VanDerWaalsContact CG-O 3.31Å; R70-S446 WeakPolarHBondContact CG-O 3.5Å; R70-S446 PolarHBondContact NE-O 3.48Å; I442-S446 VanDerWaalsContact O-CB 3.26Å; I442-S446 WeakPolarHBondContact O-CB 3.36Å; I442-S446 PolarHBondContact O-N 3.26Å; I442-S446 PolarHBondContact O-OG 2.73Å; L444-S446 VanDerWaalsContact C-N 3.32Å; L444-S446 PolarHBondContact O-N 3.17Å
447	N	95.6	Very high	93	Very high	0 Å²	0	26.8 Å²	26.8	0%	0	15%	0.145	C	C	.	.	T	Hydrogen-bonded Turn	trans	-120.8	27.9	-177.4	-63.1	-81.1	0	0	0	112.5	F34 L38 D40 H41 A443 L444 H445 F449	F34-N447 PolarHBondContact O-ND2 2.52Å; F34-N447 VanDerWaalsContact O-ND2 3.15Å; F34-N447 PolarHBondContact O-OD1 2.91Å; L38-N447 HydrophobicContact CB-CB 4.37Å; L38-N447 PolarHBondContact O-OD1 2.92Å; L38-N447 VanDerWaalsContact O-OD1 3.14Å; D40-N447 WeakPolarHBondContact OD1-CA 3.25Å; H41-N447 PolarHBondContact N-O 3Å; A443-N447 PolarHBondContact O-ND2 3.15Å; L444-N447 CarbonylContact O-C 3.59Å; L444-N447 PolarHBondContact O-N 3.42Å; L444-N447 VanDerWaalsContact O-N 3.17Å; H445-N447 PolarHBondContact O-N 3.31Å; H445-N447 VanDerWaalsContact O-N 3.12Å; N447-F449 HydrophobicContact CB-CD2 3.85Å; N447-F449 HydrophobicContact CB-CE2 4.06Å; N447-F449 WeakPolarHBondContact O-CD2 3.42Å; N447-F449 PolarHBondContact O-N 3.14Å
448	F	94.5	Very high	92.8	Very high	1 Å²	1	27 Å²	27	0%	0.004	15%	0.148	C	C	.	.	T	Hydrogen-bonded Turn	trans	57.3	18.6	179.5	-79.2	-70	0	0	0	115.6	D40 H41 A43 A45 R47 R70 W71 L444 H445	D40-F448 HydrophobicContact CB-CD2 4.5Å; H41-F448 HydrophobicContact CB-CB 4.38Å; H41-F448 PolarHBondContact CD2-O 3.33Å; H41-F448 WeakPolarHBondContact O-CB 3.31Å; A43-F448 HydrophobicContact CB-CB 4.17Å; A43-F448 HydrophobicContact CB-CD1 4.38Å; A45-F448 HydrophobicContact CB-CD1 4.48Å; A45-F448 HydrophobicContact CB-CE1 4.33Å; R47-F448 HydrophobicContact CG-CZ 4.22Å; R47-F448 VanDerWaalsContact CZ-CE2 3.43Å; R70-F448 HydrophobicContact CB-CD1 4.02Å; R70-F448 HydrophobicContact CB-CD2 4.46Å; R70-F448 HydrophobicContact CB-CE1 3.96Å; R70-F448 HydrophobicContact CB-CE2 4.45Å; R70-F448 HydrophobicContact CB-CG 4.28Å; R70-F448 HydrophobicContact CB-CZ 4.18Å; R70-F448 VanDerWaalsContact CD-CE2 3.43Å; R70-F448 HydrophobicContact CG-CD2 4.22Å; R70-F448 HydrophobicContact CG-CE2 4.27Å; R70-F448 HydrophobicContact CG-CG 4.42Å; R70-F448 HydrophobicContact CG-CZ 4.45Å; W71-F448 HydrophobicContact CD2-CD1 4.45Å; W71-F448 WeakPolarHBondContact CZ2-O 3.44Å; L444-F448 PolarHBondContact O-N 3.46Å; H445-F448 PolarHBondContact O-N 3.06Å
449	F	94.1	Very high	92.6	Very high	73 Å²	73	28.2 Å²	28.2	32%	0.32	15%	0.153	S	C	.	.			trans	-78.6	142.7	170.7	-74	-89	0	0	0	110.2	H41 W71 L444 N447 W451	H41-F449 HydrophobicContact CB-CD1 3.95Å; H41-F449 HydrophobicContact CB-CD2 4Å; H41-F449 HydrophobicContact CB-CE1 3.94Å; H41-F449 HydrophobicContact CB-CE2 3.98Å; H41-F449 HydrophobicContact CB-CG 3.99Å; H41-F449 HydrophobicContact CB-CZ 3.95Å; W71-F449 VanDerWaalsContact CZ2-C 3.44Å; W71-F449 WeakPolarHBondContact CZ2-O 3.47Å; W71-F449 PolarHBondContact NE1-O 2.93Å; L444-F449 HydrophobicContact CB-CB 3.71Å; L444-F449 HydrophobicContact CD2-CB 3.64Å; L444-F449 HydrophobicContact CD2-CD1 4.44Å; L444-F449 HydrophobicContact CD2-CD2 4.24Å; L444-F449 HydrophobicContact CD2-CG 3.87Å; L444-F449 HydrophobicContact CG-CB 4.17Å; L444-F449 WeakPolarHBondContact O-CB 3.35Å; L444-F449 PolarHBondContact O-N 3.32Å; N447-F449 HydrophobicContact CB-CD2 3.85Å; N447-F449 HydrophobicContact CB-CE2 4.06Å; N447-F449 WeakPolarHBondContact O-CD2 3.42Å; N447-F449 PolarHBondContact O-N 3.14Å; F449-W451 PolarHBondContact O-N 3.42Å
450	P	87.5	Confident	92.3	Very high	88 Å²	88	24.7 Å²	24.7	57%	0.571	14%	0.135	S	C	*	.			trans	-60.9	124.8	-178.4	23.6	-32.4	0	0	0	109.9	W71	W71-P450 HydrophobicContact CH2-CB 4.49Å
451	W	87.3	Confident	92	Very high	34 Å²	34	22.1 Å²	22.1	13%	0.129	12%	0.118	C	C	.	.			trans	-141.7	151.4	175.4	-172.2	-106.9	0	0	0	108.4	F154 L330 Y437 V440 G441 L444 F449	F154-W451 AromaticContact CZ-CD1 3.94Å; L330-W451 HydrophobicContact CD1-CE3 4.12Å; L330-W451 HydrophobicContact CD1-CH2 4.16Å; L330-W451 HydrophobicContact CD1-CZ3 3.74Å; L330-W451 HydrophobicContact CD2-CE3 4.42Å; Y437-W451 AromaticContact CD1-CH2 3.83Å; Y437-W451 HydrophobicContact CD1-CH2 3.83Å; Y437-W451 AromaticContact CD1-CZ2 3.49Å; Y437-W451 HydrophobicContact CD1-CZ2 3.49Å; Y437-W451 VanDerWaalsContact CD1-CZ2 3.49Å; Y437-W451 HydrophobicContact CD2-CH2 4.01Å; Y437-W451 HydrophobicContact CD2-CZ2 4.36Å; Y437-W451 HydrophobicContact CE1-CH2 4.17Å; Y437-W451 HydrophobicContact CE1-CZ2 4.14Å; Y437-W451 HydrophobicContact CE2-CH2 4.32Å; Y437-W451 AromaticContact CG-CH2 3.76Å; Y437-W451 HydrophobicContact CG-CH2 3.76Å; Y437-W451 AromaticContact CG-CZ2 3.64Å; Y437-W451 HydrophobicContact CG-CZ2 3.64Å; Y437-W451 WeakPolarHBondContact O-CZ2 3.31Å; V440-W451 HydrophobicContact CB-CH2 4.35Å; V440-W451 HydrophobicContact CB-CZ3 4.47Å; V440-W451 HydrophobicContact CG1-CH2 4.29Å; V440-W451 HydrophobicContact CG1-CZ3 3.92Å; G441-W451 VanDerWaalsContact CA-NE1 3.29Å; L444-W451 HydrophobicContact CB-CB 4.35Å; L444-W451 HydrophobicContact CD1-CE3 3.63Å; L444-W451 HydrophobicContact CD1-CZ3 4.02Å; F449-W451 PolarHBondContact O-N 3.42Å
452	T	70.6	Confident	91.6	Very high	7 Å²	7	24.1 Å²	24.1	4%	0.043	13%	0.129	C	C	.	.			trans	-22.5	0	-170.4	55.5	0	0	0	0	117.8	F154 L330 E378 I379 T381 Y437	F154-T452 WeakPolarHBondContact CE2-OG1 3.24Å; F154-T452 WeakPolarHBondContact CZ-O 3.33Å; F154-T452 VanDerWaalsContact CZ-OG1 3.27Å; F154-T452 WeakPolarHBondContact CZ-OG1 3.37Å; L330-T452 HydrophobicContact CD1-CG2 4.49Å; L330-T452 HydrophobicContact CD2-CG2 3.52Å; L330-T452 HydrophobicContact CG-CG2 3.65Å; E378-T452 VanDerWaalsContact CB-OXT 3.32Å; E378-T452 WeakPolarHBondContact CB-OXT 3.39Å; E378-T452 WeakPolarHBondContact CG-OXT 3.38Å; E378-T452 WeakPolarHBondContact O-CB 3.48Å; I379-T452 PolarHBondContact N-OXT 3.34Å; T381-T452 HydrophobicContact CG2-CG2 4.37Å; Y437-T452 HydrophobicContact CE1-CG2 4.23Å

Retrieved 452 of 452 residues in 355.4 ms (Link to these results)

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