A0A077Z036_TRITR Loading...

UDP-N-acetylglucosamine diphosphorylase

AlphaFold DB , UniProt , Accession A0A077Z036, Species TRITR (Trichuris trichiura, Whipworm), Gene n/a, Length 458 aa.

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Site Residue pLDDT pLDDT confidence pLDDT10 pLDDT10 confidence SASA SASA [Ų] SASA10 SASA10 [Ų] RSA RSA unformatted RSA10 RSA10 unformatted Surface Surface10 (not used) Disorder (not used) Disorder Sec. str. Secondary structure Isomer Phi (φ) Psi (ψ) Omega (ω) Chi 1 (χ1) Chi 2 (χ2) Chi 3 (χ3) Chi 4 (χ4) Chi 5 (χ5) Tau (τ) Contacts (colored by PAE) Contact details
1M42.4Very low63.6Low125 Ų12574.3 Ų74.362%0.61638%0.38SS*.  0143.10-160.8-176.790.600108.8L3 D292 L298M1-L3 HydrophobicContact CE-CD2 4.36Å; M1-L3 PolarHBondContact O-N 3.15Å; M1-D292 HydrophobicContact SD-CB 3.29Å; M1-D292 WeakPolarHBondContact SD-CB 3.27Å; M1-L298 HydrophobicContact CE-CD1 3.75Å; M1-L298 HydrophobicContact CE-CD2 3.23Å; M1-L298 HydrophobicContact CE-CG 4.15Å; M1-L298 HydrophobicContact SD-CD2 3.31Å; M1-L298 WeakPolarHBondContact SD-CD2 3.25Å
2K43.4Very low64.4Low181 Ų18171.1 Ų71.179%0.78737%0.368SS*.  trans-81.1107168.7-80.2-178.9176.31790107.4
3L50Low65.7Low30 Ų3068.6 Ų68.616%0.15736%0.364CS..  trans-60.6143.8162-76159.5000108.2M1 L41 V44 Q45 L298M1-L3 HydrophobicContact CE-CD2 4.36Å; M1-L3 PolarHBondContact O-N 3.15Å; L3-L41 HydrophobicContact CB-CD1 4.11Å; L3-L41 WeakPolarHBondContact O-CD1 3.32Å; L3-V44 HydrophobicContact CB-CG2 4.43Å; L3-V44 HydrophobicContact CD1-CB 3.92Å; L3-V44 HydrophobicContact CD1-CG2 3.54Å; L3-Q45 HydrophobicContact CB-CG 4.25Å; L3-Q45 PolarHBondContact O-NE2 3.07Å; L3-L298 HydrophobicContact CD2-CD1 3.78Å
4D65.4Low67.2Low82 Ų8268.1 Ų68.144%0.43936%0.358SS..  trans-97.4140.9170.9-169.80000109.7D6 E7 L8D4-D6 VanDerWaalsContact C-N 3.25Å; D4-D6 PolarHBondContact O-N 3.2Å; D4-D6 PolarHBondContact OD1-N 2.92Å; D4-E7 PolarHBondContact O-N 3.38Å; D4-L8 WeakPolarHBondContact O-CB 3.42Å; D4-L8 PolarHBondContact O-N 3.31Å; D4-L8 VanDerWaalsContact O-N 3.12Å
5I71Confident68.3Low24 Ų2477.5 Ų77.512%0.12339%0.386CS..Hα-helixtrans-67.4-30.2-177.4-166.366.2000111.8L8 L9 V10 K37 C40 L41I5-L8 HydrophobicContact CD1-CD2 4.22Å; I5-L8 PolarHBondContact O-N 3.49Å; I5-L9 HydrophobicContact CD1-CB 3.98Å; I5-L9 HydrophobicContact CD1-CD2 4.14Å; I5-L9 HydrophobicContact CG1-CB 4.31Å; I5-L9 HydrophobicContact CG1-CD2 4.36Å; I5-L9 WeakPolarHBondContact O-CB 3.47Å; I5-L9 PolarHBondContact O-N 2.83Å; I5-V10 PolarHBondContact O-N 3.35Å; I5-K37 HydrophobicContact CD1-CB 4.23Å; I5-K37 HydrophobicContact CD1-CG 4.47Å; I5-K37 WeakPolarHBondContact CD1-O 3.41Å; I5-K37 HydrophobicContact CG1-CB 3.82Å; I5-K37 HydrophobicContact CG1-CD 4.44Å; I5-K37 HydrophobicContact CG1-CG 3.89Å; I5-C40 HydrophobicContact CD1-CB 3.89Å; I5-L41 HydrophobicContact CB-CD1 4.18Å; I5-L41 HydrophobicContact CD1-CB 4.49Å; I5-L41 HydrophobicContact CD1-CD1 4.37Å
6D69.9Low69.5Low85 Ų8575.8 Ų75.846%0.45538%0.383SS..Iπ-helixtrans-69.1-37.4-179.1-81.4-17.1000112D4 V10 S11D4-D6 VanDerWaalsContact C-N 3.25Å; D4-D6 PolarHBondContact O-N 3.2Å; D4-D6 PolarHBondContact OD1-N 2.92Å; D6-V10 PolarHBondContact O-N 3.23Å; D6-V10 WeakPolarHBondContact OD1-CG2 3.39Å; D6-S11 VanDerWaalsContact O-CB 3.25Å; D6-S11 WeakPolarHBondContact O-CB 3.21Å; D6-S11 PolarHBondContact O-N 3.39Å; D6-S11 PolarHBondContact O-OG 3.47Å; D6-S11 VanDerWaalsContact O-OG 3.06Å
7E68Low70.6Confident110 Ų11075.4 Ų75.451%0.51438%0.376SS..Iπ-helixtrans-74.6-39.1174.2-68.9-171.8160.700112.4D4 P12D4-E7 PolarHBondContact O-N 3.38Å; E7-P12 VanDerWaalsContact O-CD 3.32Å; E7-P12 WeakPolarHBondContact O-CD 3.34Å; E7-P12 WeakPolarHBondContact O-CG 3.49Å
8L65Low71.9Confident45 Ų4577.3 Ų77.324%0.23640%0.397CS..Iπ-helixtrans-71-44.8-176.2-179.774.7000112.8D4 I5 L41 V44D4-L8 WeakPolarHBondContact O-CB 3.42Å; D4-L8 PolarHBondContact O-N 3.31Å; D4-L8 VanDerWaalsContact O-N 3.12Å; I5-L8 HydrophobicContact CD1-CD2 4.22Å; I5-L8 PolarHBondContact O-N 3.49Å; L8-L41 HydrophobicContact CD2-CD1 4.44Å; L8-V44 HydrophobicContact CD1-CB 4.43Å; L8-V44 HydrophobicContact CD1-CG1 4.18Å; L8-V44 HydrophobicContact CD1-CG2 4Å; L8-V44 HydrophobicContact CD2-CB 4.35Å; L8-V44 HydrophobicContact CD2-CG1 4.11Å; L8-V44 HydrophobicContact CD2-CG2 3.37Å; L8-V44 HydrophobicContact CG-CG2 4.3Å
9L73Confident72.9Confident40 Ų4081.4 Ų81.421%0.20942%0.415CS..Iπ-helixtrans-122.8-52.9-163.4-174.684.3000111.6I5 A13 L32 L35I5-L9 HydrophobicContact CD1-CB 3.98Å; I5-L9 HydrophobicContact CD1-CD2 4.14Å; I5-L9 HydrophobicContact CG1-CB 4.31Å; I5-L9 HydrophobicContact CG1-CD2 4.36Å; I5-L9 WeakPolarHBondContact O-CB 3.47Å; I5-L9 PolarHBondContact O-N 2.83Å; L9-A13 WeakPolarHBondContact O-CB 3.46Å; L9-A13 PolarHBondContact O-N 2.87Å; L9-A13 VanDerWaalsContact O-N 3.13Å; L9-L32 HydrophobicContact CD2-CD2 4.22Å; L9-L32 HydrophobicContact CG-CD2 4.19Å; L9-L35 HydrophobicContact CD1-CD1 4.07Å; L9-L35 HydrophobicContact CD2-CD1 3.78Å; L9-L35 HydrophobicContact CG-CD1 4.39Å
10V75.6Confident73.8Confident20 Ų2079.7 Ų79.712%0.12141%0.406CS..Iπ-helixtrans-72.8-50.6-167.2-176.60000111.6I5 D6 A13 K14I5-V10 PolarHBondContact O-N 3.35Å; D6-V10 PolarHBondContact O-N 3.23Å; D6-V10 WeakPolarHBondContact OD1-CG2 3.39Å; V10-A13 PolarHBondContact O-N 2.82Å; V10-K14 HydrophobicContact CG1-CD 4.06Å; V10-K14 HydrophobicContact CG1-CG 4.47Å; V10-K14 WeakPolarHBondContact O-CB 3.23Å; V10-K14 WeakPolarHBondContact O-CG 3.46Å; V10-K14 PolarHBondContact O-N 3.08Å
11S75.8Confident74.8Confident75 Ų7579.6 Ų79.652%0.52441%0.41SS..Hα-helixtrans-62.1-46.5-179.4-67.10000112.4D6 A13 K14 R15D6-S11 VanDerWaalsContact O-CB 3.25Å; D6-S11 WeakPolarHBondContact O-CB 3.21Å; D6-S11 PolarHBondContact O-N 3.39Å; D6-S11 PolarHBondContact O-OG 3.47Å; D6-S11 VanDerWaalsContact O-OG 3.06Å; S11-A13 PolarHBondContact O-N 2.99Å; S11-K14 PolarHBondContact O-N 2.69Å; S11-R15 PolarHBondContact O-N 3.25Å
12P73.5Confident77.3Confident36 Ų3679.9 Ų79.923%0.23441%0.414CS..Hα-helixtrans-61.6-41.9174.8-24.735.3000113.4E7 K14 R15E7-P12 VanDerWaalsContact O-CD 3.32Å; E7-P12 WeakPolarHBondContact O-CD 3.34Å; E7-P12 WeakPolarHBondContact O-CG 3.49Å; P12-K14 VanDerWaalsContact C-N 3.29Å; P12-K14 PolarHBondContact O-N 2.77Å; P12-R15 WeakPolarHBondContact O-CG 3.49Å; P12-R15 PolarHBondContact O-N 3.23Å
13A80.8Confident79.7Confident39 Ų3977.8 Ų77.832%0.32241%0.407SS..Hα-helixtrans-65.5-33.2179.800000112.4L9 V10 S11 L32L9-A13 WeakPolarHBondContact O-CB 3.46Å; L9-A13 PolarHBondContact O-N 2.87Å; L9-A13 VanDerWaalsContact O-N 3.13Å; V10-A13 PolarHBondContact O-N 2.82Å; S11-A13 PolarHBondContact O-N 2.99Å; A13-L32 HydrophobicContact CB-CD1 4.15Å; A13-L32 HydrophobicContact CB-CD2 3.74Å; A13-L32 HydrophobicContact CB-CG 4.41Å
14K86.7Confident81.9Confident62 Ų6279.8 Ų79.827%0.2742%0.415SS..THydrogen-bonded Turntrans-90.612-178.9-66.3-167.2174.1-172.10114.5V10 S11 P12 C16 W17 Q29 L32V10-K14 HydrophobicContact CG1-CD 4.06Å; V10-K14 HydrophobicContact CG1-CG 4.47Å; V10-K14 WeakPolarHBondContact O-CB 3.23Å; V10-K14 WeakPolarHBondContact O-CG 3.46Å; V10-K14 PolarHBondContact O-N 3.08Å; S11-K14 PolarHBondContact O-N 2.69Å; P12-K14 VanDerWaalsContact C-N 3.29Å; P12-K14 PolarHBondContact O-N 2.77Å; K14-C16 PolarHBondContact O-N 3.42Å; K14-C16 VanDerWaalsContact O-N 3.11Å; K14-W17 HydrophobicContact CB-CB 4.18Å; K14-W17 HydrophobicContact CB-CE3 4.18Å; K14-W17 HydrophobicContact CD-CD2 4.18Å; K14-W17 HydrophobicContact CD-CE3 3.77Å; K14-W17 HydrophobicContact CD-CZ3 4.06Å; K14-W17 HydrophobicContact CG-CD2 4.35Å; K14-W17 HydrophobicContact CG-CE3 3.63Å; K14-W17 HydrophobicContact CG-CZ3 4.1Å; K14-W17 WeakPolarHBondContact O-CB 3.45Å; K14-W17 PolarHBondContact O-N 2.98Å; K14-Q29 VanDerWaalsContact CE-OE1 3.24Å; K14-L32 HydrophobicContact CG-CD1 4.08Å
15R84.4Confident83.3Confident209 Ų20978 Ų7879%0.78940%0.404SS*.THydrogen-bonded Turntrans-57.5-29.7-177.374.5-178.1-173.9-169.6-1.9114.8S11 P12S11-R15 PolarHBondContact O-N 3.25Å; P12-R15 WeakPolarHBondContact O-CG 3.49Å; P12-R15 PolarHBondContact O-N 3.23Å
16C86.2Confident84.4Confident49 Ų4983.1 Ų83.133%0.33143%0.428SS..THydrogen-bonded Turntrans-104.215.7178.6-62.70000112.3K14 S18 E19K14-C16 PolarHBondContact O-N 3.42Å; K14-C16 VanDerWaalsContact O-N 3.11Å; C16-S18 VanDerWaalsContact C-N 3.26Å; C16-S18 PolarHBondContact O-N 3.37Å; C16-S18 VanDerWaalsContact O-N 3.14Å; C16-E19 WeakPolarHBondContact O-CB 3.36Å; C16-E19 PolarHBondContact O-N 2.9Å
17W89.8Confident85.6Confident70 Ų7085.3 Ų85.327%0.26543%0.43SS..G310 helixtrans-54.5-39.5-168.7-173.3-91.1000113.7K14 E19 L20 Q25 L28 Q29K14-W17 HydrophobicContact CB-CB 4.18Å; K14-W17 HydrophobicContact CB-CE3 4.18Å; K14-W17 HydrophobicContact CD-CD2 4.18Å; K14-W17 HydrophobicContact CD-CE3 3.77Å; K14-W17 HydrophobicContact CD-CZ3 4.06Å; K14-W17 HydrophobicContact CG-CD2 4.35Å; K14-W17 HydrophobicContact CG-CE3 3.63Å; K14-W17 HydrophobicContact CG-CZ3 4.1Å; K14-W17 WeakPolarHBondContact O-CB 3.45Å; K14-W17 PolarHBondContact O-N 2.98Å; W17-E19 VanDerWaalsContact C-N 3.25Å; W17-E19 PolarHBondContact O-N 3.4Å; W17-L20 PolarHBondContact O-N 3.25Å; W17-Q25 HydrophobicContact CD2-CG 4.12Å; W17-Q25 HydrophobicContact CE3-CG 4.47Å; W17-Q25 HydrophobicContact CH2-CB 3.81Å; W17-Q25 HydrophobicContact CH2-CG 4.29Å; W17-Q25 VanDerWaalsContact CH2-O 3.32Å; W17-Q25 WeakPolarHBondContact CH2-O 3.44Å; W17-Q25 HydrophobicContact CZ2-CB 3.69Å; W17-Q25 HydrophobicContact CZ2-CG 3.92Å; W17-Q25 HydrophobicContact CZ3-CB 4.34Å; W17-Q25 PolarHBondContact O-NE2 3.03Å; W17-L28 HydrophobicContact CE3-CD2 3.85Å; W17-L28 HydrophobicContact CZ3-CB 4.23Å; W17-L28 HydrophobicContact CZ3-CD2 3.88Å; W17-L28 HydrophobicContact CZ3-CG 4.12Å; W17-Q29 HydrophobicContact CH2-CB 4.11Å
18S92.5Very high86.7Confident109 Ų10981.7 Ų81.776%0.76241%0.414SS*.G310 helixtrans-69.2-17.8179.251.50000114.7C16C16-S18 VanDerWaalsContact C-N 3.26Å; C16-S18 PolarHBondContact O-N 3.37Å; C16-S18 VanDerWaalsContact O-N 3.14Å
19E92.5Very high88.1Confident155 Ų15582.1 Ų82.172%0.72441%0.414SS*.G310 helixtrans-93.1-12.5-179.9-62.5172-159.800112.4C16 W17C16-E19 WeakPolarHBondContact O-CB 3.36Å; C16-E19 PolarHBondContact O-N 2.9Å; W17-E19 VanDerWaalsContact C-N 3.25Å; W17-E19 PolarHBondContact O-N 3.4Å
20L90.4Very high89Confident47 Ų4786.6 Ų86.625%0.24643%0.434CS..SBendtrans-81.1140.7-178.8-62.3-177.3000111.2W17 E24 Q25 L28W17-L20 PolarHBondContact O-N 3.25Å; L20-E24 HydrophobicContact CB-CB 3.85Å; L20-E24 HydrophobicContact CD1-CB 4.45Å; L20-E24 HydrophobicContact CD2-CB 4.1Å; L20-E24 HydrophobicContact CG-CB 4.34Å; L20-Q25 HydrophobicContact CB-CG 3.65Å; L20-Q25 HydrophobicContact CD1-CG 4.4Å; L20-Q25 PolarHBondContact O-NE2 2.92Å; L20-L28 HydrophobicContact CD1-CD2 3.76Å
21T95.3Very high89.8Confident78 Ų7891.4 Ų91.448%0.47946%0.456SS..  trans-63.3160.8165.561.60000111E23 E24 Q25T21-E23 PolarHBondContact O-N 3.48Å; T21-E24 WeakPolarHBondContact CB-OE2 3.41Å; T21-E24 WeakPolarHBondContact CG2-OE2 3.37Å; T21-E24 PolarHBondContact N-OE2 2.89Å; T21-E24 WeakPolarHBondContact O-CB 3.29Å; T21-E24 PolarHBondContact O-N 3.05Å; T21-E24 VanDerWaalsContact OG1-CD 3.23Å; T21-E24 VanDerWaalsContact OG1-CG 3.24Å; T21-E24 WeakPolarHBondContact OG1-CG 3.27Å; T21-E24 PolarHBondContact OG1-N 2.85Å; T21-E24 PolarHBondContact OG1-OE2 3Å; T21-Q25 PolarHBondContact O-N 3.34Å
22N94.7Very high90.4Very high131 Ų13188.2 Ų88.270%0.70143%0.433SS*.Hα-helixtrans-56.1-38.1179.3-69.4-19.7000112.9Q26N22-Q26 PolarHBondContact O-N 3.04Å
23E93.9Very high91.1Very high137 Ų13790.8 Ų90.864%0.6444%0.444SS*.Hα-helixtrans-68.4-37.8176.3-72-174.6170.200112.4T21 R27T21-E23 PolarHBondContact O-N 3.48Å; E23-R27 WeakPolarHBondContact O-CB 3.37Å; E23-R27 VanDerWaalsContact O-CG 3.31Å; E23-R27 WeakPolarHBondContact O-CG 3.29Å; E23-R27 PolarHBondContact O-N 3.03Å; E23-R27 PolarHBondContact O-NE 3.47Å
24E95.2Very high91.5Very high73 Ų7393.5 Ų93.534%0.34146%0.461SS..Hα-helixtrans-67.6-42174.9-71.7166.5144.800112L20 T21 Q26 R27 L28L20-E24 HydrophobicContact CB-CB 3.85Å; L20-E24 HydrophobicContact CD1-CB 4.45Å; L20-E24 HydrophobicContact CD2-CB 4.1Å; L20-E24 HydrophobicContact CG-CB 4.34Å; T21-E24 WeakPolarHBondContact CB-OE2 3.41Å; T21-E24 WeakPolarHBondContact CG2-OE2 3.37Å; T21-E24 PolarHBondContact N-OE2 2.89Å; T21-E24 WeakPolarHBondContact O-CB 3.29Å; T21-E24 PolarHBondContact O-N 3.05Å; T21-E24 VanDerWaalsContact OG1-CD 3.23Å; T21-E24 VanDerWaalsContact OG1-CG 3.24Å; T21-E24 WeakPolarHBondContact OG1-CG 3.27Å; T21-E24 PolarHBondContact OG1-N 2.85Å; T21-E24 PolarHBondContact OG1-OE2 3Å; E24-Q26 PolarHBondContact O-N 3.34Å; E24-R27 PolarHBondContact O-N 3.23Å; E24-L28 WeakPolarHBondContact O-CB 3.4Å; E24-L28 PolarHBondContact O-N 3.19Å
25Q95.6Very high91.3Very high43 Ų4394 Ų9420%0.20147%0.466CS..Hα-helixtrans-59.7-45.8174.4-71.9-176.61.100111.4W17 L20 T21 L28 Q29W17-Q25 HydrophobicContact CD2-CG 4.12Å; W17-Q25 HydrophobicContact CE3-CG 4.47Å; W17-Q25 HydrophobicContact CH2-CB 3.81Å; W17-Q25 HydrophobicContact CH2-CG 4.29Å; W17-Q25 VanDerWaalsContact CH2-O 3.32Å; W17-Q25 WeakPolarHBondContact CH2-O 3.44Å; W17-Q25 HydrophobicContact CZ2-CB 3.69Å; W17-Q25 HydrophobicContact CZ2-CG 3.92Å; W17-Q25 HydrophobicContact CZ3-CB 4.34Å; W17-Q25 PolarHBondContact O-NE2 3.03Å; L20-Q25 HydrophobicContact CB-CG 3.65Å; L20-Q25 HydrophobicContact CD1-CG 4.4Å; L20-Q25 PolarHBondContact O-NE2 2.92Å; T21-Q25 PolarHBondContact O-N 3.34Å; Q25-L28 PolarHBondContact O-N 2.87Å; Q25-Q29 WeakPolarHBondContact O-CB 3.42Å; Q25-Q29 PolarHBondContact O-N 2.94Å
26Q93.7Very high91.3Very high133 Ų13388 Ų8862%0.62145%0.45SS*.Hα-helixtrans-61.8-44.4176.1-80.8-174.5-4.100112.1N22 E24 L28 Q29 Q30N22-Q26 PolarHBondContact O-N 3.04Å; E24-Q26 PolarHBondContact O-N 3.34Å; Q26-L28 PolarHBondContact O-N 3.35Å; Q26-Q29 PolarHBondContact O-N 2.65Å; Q26-Q30 WeakPolarHBondContact O-CB 3.47Å; Q26-Q30 WeakPolarHBondContact O-CG 3.31Å; Q26-Q30 PolarHBondContact O-N 3.39Å
27R95.6Very high90.8Very high130 Ų13089.1 Ų89.149%0.49145%0.449SS..Hα-helixtrans-61.9-42177.1-75.7-179-67.8-167.61.7112.3E23 E24 Q31E23-R27 WeakPolarHBondContact O-CB 3.37Å; E23-R27 VanDerWaalsContact O-CG 3.31Å; E23-R27 WeakPolarHBondContact O-CG 3.29Å; E23-R27 PolarHBondContact O-N 3.03Å; E23-R27 PolarHBondContact O-NE 3.47Å; E24-R27 PolarHBondContact O-N 3.23Å; R27-Q31 WeakPolarHBondContact O-CG 3.14Å; R27-Q31 PolarHBondContact O-N 2.9Å; R27-Q31 VanDerWaalsContact O-N 3.11Å; R27-Q31 PolarHBondContact O-NE2 2.88Å
28L91.5Very high89.9Confident34 Ų3488.2 Ų88.218%0.17845%0.453CS..Hα-helixtrans-67.1-41.4176.8179.458.9000111.4W17 L20 E24 Q25 Q26 Q31 L32W17-L28 HydrophobicContact CE3-CD2 3.85Å; W17-L28 HydrophobicContact CZ3-CB 4.23Å; W17-L28 HydrophobicContact CZ3-CD2 3.88Å; W17-L28 HydrophobicContact CZ3-CG 4.12Å; L20-L28 HydrophobicContact CD1-CD2 3.76Å; E24-L28 WeakPolarHBondContact O-CB 3.4Å; E24-L28 PolarHBondContact O-N 3.19Å; Q25-L28 PolarHBondContact O-N 2.87Å; Q26-L28 PolarHBondContact O-N 3.35Å; L28-Q31 WeakPolarHBondContact O-CB 3.48Å; L28-Q31 PolarHBondContact O-N 3.33Å; L28-L32 HydrophobicContact CD1-CG 4.47Å; L28-L32 HydrophobicContact CG-CD1 4.35Å; L28-L32 WeakPolarHBondContact O-CG 3.47Å; L28-L32 PolarHBondContact O-N 3.35Å
29Q93Very high88.7Confident54 Ų5491.3 Ų91.325%0.25245%0.448SS..Hα-helixtrans-62.7-44.9176.7-168.254.956.800111.6K14 W17 Q25 Q26 Q31 L32 D33K14-Q29 VanDerWaalsContact CE-OE1 3.24Å; W17-Q29 HydrophobicContact CH2-CB 4.11Å; Q25-Q29 WeakPolarHBondContact O-CB 3.42Å; Q25-Q29 PolarHBondContact O-N 2.94Å; Q26-Q29 PolarHBondContact O-N 2.65Å; Q29-Q31 VanDerWaalsContact C-N 3.3Å; Q29-Q31 PolarHBondContact O-N 2.89Å; Q29-L32 PolarHBondContact O-N 3.47Å; Q29-L32 VanDerWaalsContact O-N 3.15Å; Q29-D33 WeakPolarHBondContact CG-OD2 3.23Å; Q29-D33 PolarHBondContact NE2-OD1 3.09Å; Q29-D33 PolarHBondContact NE2-OD2 3.25Å; Q29-D33 WeakPolarHBondContact O-CB 3.36Å; Q29-D33 PolarHBondContact O-N 3.48Å
30Q92.5Very high87.4Confident135 Ų13585.6 Ų85.663%0.63143%0.425SS*.Hα-helixtrans-58.8-41.1175.5-77.7178.5-5.300112Q26 D33 S34Q26-Q30 WeakPolarHBondContact O-CB 3.47Å; Q26-Q30 WeakPolarHBondContact O-CG 3.31Å; Q26-Q30 PolarHBondContact O-N 3.39Å; Q30-D33 PolarHBondContact O-N 3.38Å; Q30-S34 VanDerWaalsContact O-CB 3.3Å; Q30-S34 WeakPolarHBondContact O-CB 3.44Å; Q30-S34 PolarHBondContact O-N 3.49Å
31Q92.7Very high86Confident121 Ų12185 Ų8557%0.56542%0.422SS*.Hα-helixtrans-62-48.7173.9-73.8173.56300111.2R27 L28 Q29 D33 S34 L35R27-Q31 WeakPolarHBondContact O-CG 3.14Å; R27-Q31 PolarHBondContact O-N 2.9Å; R27-Q31 VanDerWaalsContact O-N 3.11Å; R27-Q31 PolarHBondContact O-NE2 2.88Å; L28-Q31 WeakPolarHBondContact O-CB 3.48Å; L28-Q31 PolarHBondContact O-N 3.33Å; Q29-Q31 VanDerWaalsContact C-N 3.3Å; Q29-Q31 PolarHBondContact O-N 2.89Å; Q31-D33 VanDerWaalsContact C-N 3.3Å; Q31-D33 PolarHBondContact O-N 3.3Å; Q31-S34 PolarHBondContact O-N 3.35Å; Q31-S34 PolarHBondContact O-OG 2.99Å; Q31-L35 WeakPolarHBondContact O-CG 3.28Å; Q31-L35 PolarHBondContact O-N 3.38Å
32L87.3Confident84.2Confident8 Ų888.3 Ų88.34%0.04243%0.426CS..Hα-helixtrans-62.3-35179.3-72.3174.5000113.3L9 A13 K14 L28 Q29 L35 K37L9-L32 HydrophobicContact CD2-CD2 4.22Å; L9-L32 HydrophobicContact CG-CD2 4.19Å; A13-L32 HydrophobicContact CB-CD1 4.15Å; A13-L32 HydrophobicContact CB-CD2 3.74Å; A13-L32 HydrophobicContact CB-CG 4.41Å; K14-L32 HydrophobicContact CG-CD1 4.08Å; L28-L32 HydrophobicContact CD1-CG 4.47Å; L28-L32 HydrophobicContact CG-CD1 4.35Å; L28-L32 WeakPolarHBondContact O-CG 3.47Å; L28-L32 PolarHBondContact O-N 3.35Å; Q29-L32 PolarHBondContact O-N 3.47Å; Q29-L32 VanDerWaalsContact O-N 3.15Å; L32-L35 HydrophobicContact CD2-CD1 4.42Å; L32-K37 WeakPolarHBondContact O-CE 3.41Å
33D88.7Confident82.3Confident90 Ų9082.9 Ų82.948%0.48140%0.4SS..Hα-helixtrans-81.2-22.5178.6-66.9-27.8000113.1Q29 Q30 Q31 L35 K37Q29-D33 WeakPolarHBondContact CG-OD2 3.23Å; Q29-D33 PolarHBondContact NE2-OD1 3.09Å; Q29-D33 PolarHBondContact NE2-OD2 3.25Å; Q29-D33 WeakPolarHBondContact O-CB 3.36Å; Q29-D33 PolarHBondContact O-N 3.48Å; Q30-D33 PolarHBondContact O-N 3.38Å; Q31-D33 VanDerWaalsContact C-N 3.3Å; Q31-D33 PolarHBondContact O-N 3.3Å; D33-L35 PolarHBondContact O-N 3.19Å; D33-K37 IonicContact OD1-NZ 3.78Å; D33-K37 PolarHBondContact OD1-NZ 3.35Å
34S89Confident80.3Confident95 Ų9578.8 Ų78.866%0.66438%0.384SS*.Hα-helixtrans-71.9-17.3172.177.60000113.3Q30 Q31Q30-S34 VanDerWaalsContact O-CB 3.3Å; Q30-S34 WeakPolarHBondContact O-CB 3.44Å; Q30-S34 PolarHBondContact O-N 3.49Å; Q31-S34 PolarHBondContact O-N 3.35Å; Q31-S34 PolarHBondContact O-OG 2.99Å
35L83.3Confident78.1Confident73 Ų7377.5 Ų77.538%0.38238%0.378SS..SBendtrans-78.7131.9179.3-66.7170.4000111L9 Q31 L32 D33 K37L9-L35 HydrophobicContact CD1-CD1 4.07Å; L9-L35 HydrophobicContact CD2-CD1 3.78Å; L9-L35 HydrophobicContact CG-CD1 4.39Å; Q31-L35 WeakPolarHBondContact O-CG 3.28Å; Q31-L35 PolarHBondContact O-N 3.38Å; L32-L35 HydrophobicContact CD2-CD1 4.42Å; D33-L35 PolarHBondContact O-N 3.19Å; L35-K37 VanDerWaalsContact C-N 3.26Å; L35-K37 PolarHBondContact O-N 3.17Å
36D83.1Confident75.8Confident83 Ų8379 Ų7944%0.44439%0.389SS..  trans-70.287.1165.5-179.8-8.1000109.3S38 R39 C40D36-S38 PolarHBondContact O-N 2.93Å; D36-S38 WeakPolarHBondContact OD1-CB 3.39Å; D36-S38 PolarHBondContact OD1-N 3.11Å; D36-S38 VanDerWaalsContact OD1-N 3.1Å; D36-S38 PolarHBondContact OD1-OG 2.56Å; D36-R39 HydrophobicContact CB-CB 3.87Å; D36-R39 WeakPolarHBondContact O-CA 3.45Å; D36-R39 WeakPolarHBondContact O-CB 3.16Å; D36-R39 PolarHBondContact O-N 3.46Å; D36-R39 PolarHBondContact OD1-N 2.92Å; D36-R39 VanDerWaalsContact OD2-CB 3.27Å; D36-R39 WeakPolarHBondContact OD2-CB 3.34Å; D36-C40 PolarHBondContact O-N 2.81Å; D36-C40 PolarHBondContact O-SG 3.27Å
37K77.3Confident73.6Confident72 Ų7276.2 Ų76.231%0.31338%0.383SS..Hα-helixtrans-51.6-36.5178.5-74.4174.4-166.4168.70112.1I5 L32 D33 L35 L41I5-K37 HydrophobicContact CD1-CB 4.23Å; I5-K37 HydrophobicContact CD1-CG 4.47Å; I5-K37 WeakPolarHBondContact CD1-O 3.41Å; I5-K37 HydrophobicContact CG1-CB 3.82Å; I5-K37 HydrophobicContact CG1-CD 4.44Å; I5-K37 HydrophobicContact CG1-CG 3.89Å; L32-K37 WeakPolarHBondContact O-CE 3.41Å; D33-K37 IonicContact OD1-NZ 3.78Å; D33-K37 PolarHBondContact OD1-NZ 3.35Å; L35-K37 VanDerWaalsContact C-N 3.26Å; L35-K37 PolarHBondContact O-N 3.17Å; K37-L41 WeakPolarHBondContact O-CB 3.29Å; K37-L41 PolarHBondContact O-N 3.18Å
38S69.5Low71.3Confident52 Ų5278.5 Ų78.536%0.36440%0.404SS..Hα-helixtrans-67.7-40.2177.384.60000112D36 L41 R42D36-S38 PolarHBondContact O-N 2.93Å; D36-S38 WeakPolarHBondContact OD1-CB 3.39Å; D36-S38 PolarHBondContact OD1-N 3.11Å; D36-S38 VanDerWaalsContact OD1-N 3.1Å; D36-S38 PolarHBondContact OD1-OG 2.56Å; S38-L41 PolarHBondContact O-N 3.1Å; S38-R42 WeakPolarHBondContact O-CB 3.41Å; S38-R42 WeakPolarHBondContact O-CG 3.3Å; S38-R42 PolarHBondContact O-N 3.31Å; S38-R42 PolarHBondContact OG-NH2 3.4Å
39R67.7Low69.4Low173 Ų17377.8 Ų77.865%0.65340%0.402SS*.Hα-helixtrans-69.9-42.2176.2-179.4179176.9-174-1.6111.3D36 L41 R42 A43D36-R39 HydrophobicContact CB-CB 3.87Å; D36-R39 WeakPolarHBondContact O-CA 3.45Å; D36-R39 WeakPolarHBondContact O-CB 3.16Å; D36-R39 PolarHBondContact O-N 3.46Å; D36-R39 PolarHBondContact OD1-N 2.92Å; D36-R39 VanDerWaalsContact OD2-CB 3.27Å; D36-R39 WeakPolarHBondContact OD2-CB 3.34Å; R39-L41 VanDerWaalsContact C-N 3.3Å; R39-L41 PolarHBondContact O-N 3.02Å; R39-R42 PolarHBondContact O-N 3.01Å; R39-A43 VanDerWaalsContact O-CB 3.28Å; R39-A43 WeakPolarHBondContact O-CB 3.1Å; R39-A43 PolarHBondContact O-N 3.26Å
40C65Low68Low36 Ų3679.9 Ų79.924%0.24341%0.41CS..Hα-helixtrans-57-46.1172.6-65.90000111.1I5 D36 A43 V44I5-C40 HydrophobicContact CD1-CB 3.89Å; D36-C40 PolarHBondContact O-N 2.81Å; D36-C40 PolarHBondContact O-SG 3.27Å; C40-A43 PolarHBondContact O-N 3.04Å; C40-V44 PolarHBondContact O-N 2.93Å
41L61.7Low66.6Low35 Ų3577 Ų7718%0.18340%0.404CS..Hα-helixtrans-64.8-46.9178.9-156.667.3000112.1L3 I5 L8 K37 S38 R39 A43 V44 Q45L3-L41 HydrophobicContact CB-CD1 4.11Å; L3-L41 WeakPolarHBondContact O-CD1 3.32Å; I5-L41 HydrophobicContact CB-CD1 4.18Å; I5-L41 HydrophobicContact CD1-CB 4.49Å; I5-L41 HydrophobicContact CD1-CD1 4.37Å; L8-L41 HydrophobicContact CD2-CD1 4.44Å; K37-L41 WeakPolarHBondContact O-CB 3.29Å; K37-L41 PolarHBondContact O-N 3.18Å; S38-L41 PolarHBondContact O-N 3.1Å; R39-L41 VanDerWaalsContact C-N 3.3Å; R39-L41 PolarHBondContact O-N 3.02Å; L41-A43 VanDerWaalsContact C-N 3.25Å; L41-A43 PolarHBondContact O-N 2.85Å; L41-V44 VanDerWaalsContact O-CG2 3.27Å; L41-V44 WeakPolarHBondContact O-CG2 3.37Å; L41-V44 PolarHBondContact O-N 3.38Å; L41-Q45 VanDerWaalsContact CD2-NE2 3.29Å; L41-Q45 HydrophobicContact CG-CG 4.11Å; L41-Q45 VanDerWaalsContact O-CB 3.26Å; L41-Q45 WeakPolarHBondContact O-CB 3.3Å; L41-Q45 VanDerWaalsContact O-CG 3.24Å; L41-Q45 WeakPolarHBondContact O-CG 3.42Å; L41-Q45 PolarHBondContact O-N 3.43Å
42R58.5Low65.6Low146 Ų14671.7 Ų71.755%0.55138%0.38SS*.Hα-helixtrans-62.9-31.2175.8-76.4-172.5-62.5-108.5-7.1112.9S38 R39 V44S38-R42 WeakPolarHBondContact O-CB 3.41Å; S38-R42 WeakPolarHBondContact O-CG 3.3Å; S38-R42 PolarHBondContact O-N 3.31Å; S38-R42 PolarHBondContact OG-NH2 3.4Å; R39-R42 PolarHBondContact O-N 3.01Å; R42-V44 VanDerWaalsContact C-N 3.26Å; R42-V44 PolarHBondContact O-N 2.9Å
43A54.3Low65.1Low18 Ų1872.3 Ų72.315%0.14938%0.383CS..Hα-helixtrans-69.3-24.9179.300000112.9R39 C40 L41 D272R39-A43 VanDerWaalsContact O-CB 3.28Å; R39-A43 WeakPolarHBondContact O-CB 3.1Å; R39-A43 PolarHBondContact O-N 3.26Å; C40-A43 PolarHBondContact O-N 3.04Å; L41-A43 VanDerWaalsContact C-N 3.25Å; L41-A43 PolarHBondContact O-N 2.85Å; A43-D272 PolarHBondContact O-N 3.26Å; A43-D272 VanDerWaalsContact O-N 3.16Å
44V50.4Low64.6Low51 Ų5169.9 Ų69.931%0.30937%0.367SS..Hα-helixtrans-108-23.5178.5-60.30000114.1L3 L8 C40 L41 R42 V46L3-V44 HydrophobicContact CB-CG2 4.43Å; L3-V44 HydrophobicContact CD1-CB 3.92Å; L3-V44 HydrophobicContact CD1-CG2 3.54Å; L8-V44 HydrophobicContact CD1-CB 4.43Å; L8-V44 HydrophobicContact CD1-CG1 4.18Å; L8-V44 HydrophobicContact CD1-CG2 4Å; L8-V44 HydrophobicContact CD2-CB 4.35Å; L8-V44 HydrophobicContact CD2-CG1 4.11Å; L8-V44 HydrophobicContact CD2-CG2 3.37Å; L8-V44 HydrophobicContact CG-CG2 4.3Å; C40-V44 PolarHBondContact O-N 2.93Å; L41-V44 VanDerWaalsContact O-CG2 3.27Å; L41-V44 WeakPolarHBondContact O-CG2 3.37Å; L41-V44 PolarHBondContact O-N 3.38Å; R42-V44 VanDerWaalsContact C-N 3.26Å; R42-V44 PolarHBondContact O-N 2.9Å; V44-V46 PolarHBondContact O-N 3.32Å
45Q49.1Very low63.8Low45 Ų4571.2 Ų71.221%0.2136%0.363CS..SBendtrans-67.9130174.5-80.5-179.1-8.400108.3L3 L41 P47L3-Q45 HydrophobicContact CB-CG 4.25Å; L3-Q45 PolarHBondContact O-NE2 3.07Å; L41-Q45 VanDerWaalsContact CD2-NE2 3.29Å; L41-Q45 HydrophobicContact CG-CG 4.11Å; L41-Q45 VanDerWaalsContact O-CB 3.26Å; L41-Q45 WeakPolarHBondContact O-CB 3.3Å; L41-Q45 VanDerWaalsContact O-CG 3.24Å; L41-Q45 WeakPolarHBondContact O-CG 3.42Å; L41-Q45 PolarHBondContact O-N 3.43Å; Q45-P47 WeakPolarHBondContact O-CD 3.49Å
46V48.6Very low63.2Low74 Ų7474.3 Ų74.345%0.44837%0.374SS..  trans-78.797.5173-177.50000107.6V44 L48 Q270V44-V46 PolarHBondContact O-N 3.32Å; V46-L48 PolarHBondContact O-N 3.33Å; V46-Q270 HydrophobicContact CB-CG 4.46Å; V46-Q270 HydrophobicContact CG1-CG 4.22Å; V46-Q270 HydrophobicContact CG2-CG 4.45Å
47P46.9Very low62.5Low75 Ų7573.2 Ų73.249%0.48737%0.366SS..  trans-51.2138.2155.919-30.4000106.9Q45 C49 Q270Q45-P47 WeakPolarHBondContact O-CD 3.49Å; P47-C49 PolarHBondContact O-N 3.36Å; P47-Q270 VanDerWaalsContact CD-CD 3.41Å; P47-Q270 PolarHBondContact O-NE2 3.18Å
48L47.4Very low61.9Low178 Ų17877.2 Ų77.293%0.93238%0.383SS*.  trans-49.791.5-177.8-77124.6000109.7V46V46-L48 PolarHBondContact O-N 3.33Å
49C52.5Low61.5Low19 Ų1981.1 Ų81.113%0.12840%0.395CS..  trans-54148.6151.7173.80000105.1P47 C51 F367P47-C49 PolarHBondContact O-N 3.36Å; C49-C51 PolarHBondContact O-N 2.87Å; C49-F367 PolarHBondContact SG-O 3.49Å
50K62.4Low61Low99 Ų9976.6 Ų76.643%0.4339%0.39SS..EExtended strand (participates in β ladder)trans-64.182.1169.7-73.6-179.5179.8-171.30107.7M247 A368 V369K50-M247 HydrophobicContact CB-CE 3.66Å; K50-M247 HydrophobicContact CB-CG 4.46Å; K50-M247 HydrophobicContact CD-CB 3.84Å; K50-M247 HydrophobicContact CD-CE 3.76Å; K50-M247 HydrophobicContact CD-CG 4.07Å; K50-M247 HydrophobicContact CD-SD 3.88Å; K50-M247 HydrophobicContact CG-CE 3.79Å; K50-M247 PolarHBondContact NZ-O 2.99Å; K50-A368 HydrophobicContact CB-CB 4.26Å; K50-V369 PolarHBondContact O-N 3.25Å
51C63.4Low61.6Low74 Ų7477 Ų7750%0.539%0.39SS..EExtended strand (participates in β ladder)trans-92.8124.6176.6-66.50000107.9C49 V369C49-C51 PolarHBondContact O-N 2.87Å; C51-V369 VanDerWaalsContact CA-O 3.31Å; C51-V369 WeakPolarHBondContact CA-O 3.44Å
52C72.4Confident62.5Low9 Ų977.5 Ų77.56%0.06139%0.393CS..EExtended strand (participates in β ladder)trans-123.8137.2175.9174.50000107.9E57 F243 V369 L370 E371C52-E57 VanDerWaalsContact SG-CD 3.55Å; C52-E57 WeakPolarHBondContact SG-CG 3.37Å; C52-E57 PolarHBondContact SG-OE1 3.33Å; C52-F243 HydrophobicContact CB-CD2 4.08Å; C52-F243 HydrophobicContact CB-CE2 3.35Å; C52-F243 HydrophobicContact CB-CZ 3.9Å; C52-V369 PolarHBondContact N-O 3.47Å; C52-L370 HydrophobicContact CB-CD1 4.18Å; C52-E371 PolarHBondContact O-N 3.35Å
53N76Confident63.8Low22 Ų2276.2 Ų76.212%0.11839%0.393CS..EExtended strand (participates in β ladder)trans-104.7115.2168.7171.3-36.5000107E55 K56 E57 E371N53-E55 PolarHBondContact O-N 2.99Å; N53-E55 WeakPolarHBondContact OD1-CB 3.28Å; N53-E55 PolarHBondContact OD1-N 3.3Å; N53-K56 HydrophobicContact CB-CB 4.31Å; N53-K56 HydrophobicContact CB-CD 4.25Å; N53-K56 HydrophobicContact CB-CG 4.34Å; N53-K56 PolarHBondContact O-N 3.3Å; N53-K56 VanDerWaalsContact O-N 3.07Å; N53-K56 PolarHBondContact OD1-N 2.82Å; N53-E57 PolarHBondContact O-N 2.97Å; N53-E371 HydrophobicContact CB-CB 4.3Å; N53-E371 PolarHBondContact ND2-OE1 2.84Å
54R78.1Confident65.6Low38 Ų3878.7 Ų78.714%0.14340%0.401CS..G310 helixtrans-53.6-38.1-175-176175.8-17815313.6113.4R234 D237 W239 L370 E371 E377R54-R234 VanDerWaalsContact CZ-NH1 3.3Å; R54-R234 VanDerWaalsContact NH2-NH1 3.14Å; R54-D237 IonicContact NH1-OD1 2.9Å; R54-D237 IonicContact NH1-OD2 2.94Å; R54-D237 PolarHBondContact NH1-OD2 2.86Å; R54-D237 VanDerWaalsContact NH1-OD2 3.1Å; R54-W239 HydrophobicContact CB-CH2 4.12Å; R54-W239 HydrophobicContact CB-CZ2 4.3Å; R54-W239 HydrophobicContact CG-CD2 4.27Å; R54-W239 HydrophobicContact CG-CE3 4.46Å; R54-W239 HydrophobicContact CG-CH2 4.01Å; R54-W239 HydrophobicContact CG-CZ2 3.75Å; R54-W239 HydrophobicContact CG-CZ3 4.38Å; R54-W239 VanDerWaalsContact NH2-CB 3.28Å; R54-L370 HydrophobicContact CB-CD1 4.22Å; R54-E371 PolarHBondContact N-O 3.45Å; R54-E377 IonicContact CZ-OE1 3.09Å; R54-E377 IonicContact NH1-OE1 2.56Å; R54-E377 PolarHBondContact NH1-OE1 3.05Å
55E72.6Confident67.7Low124 Ų12476.7 Ų76.758%0.57939%0.388SS*.G310 helixtrans-74-28.2-177.7-60.3-171.7141.800113.3N53 N373N53-E55 PolarHBondContact O-N 2.99Å; N53-E55 WeakPolarHBondContact OD1-CB 3.28Å; N53-E55 PolarHBondContact OD1-N 3.3Å; E55-N373 HydrophobicContact CG-CB 4.43Å; E55-N373 WeakPolarHBondContact OE1-CB 3.22Å; E55-N373 PolarHBondContact OE1-ND2 2.89Å
56K69.5Low69.8Low138 Ų13876.7 Ų76.760%0.639%0.394SS*.G310 helixtrans-88.2-6.8-176.9-64.8-178.4-177.6176.50113N53N53-K56 HydrophobicContact CB-CB 4.31Å; N53-K56 HydrophobicContact CB-CD 4.25Å; N53-K56 HydrophobicContact CB-CG 4.34Å; N53-K56 PolarHBondContact O-N 3.3Å; N53-K56 VanDerWaalsContact O-N 3.07Å; N53-K56 PolarHBondContact OD1-N 2.82Å
57E68.6Low72Confident59 Ų5975.1 Ų75.128%0.27639%0.386SS..SBendtrans-75.4146.8179.8-69.7-55.9156.400112.6C52 N53 L61 W239C52-E57 VanDerWaalsContact SG-CD 3.55Å; C52-E57 WeakPolarHBondContact SG-CG 3.37Å; C52-E57 PolarHBondContact SG-OE1 3.33Å; N53-E57 PolarHBondContact O-N 2.97Å; E57-L61 WeakPolarHBondContact OE2-CD1 3.46Å; E57-W239 HydrophobicContact CG-CH2 4.45Å; E57-W239 HydrophobicContact CG-CZ2 4.49Å
58K64.7Low74.4Confident156 Ų15673.4 Ų73.468%0.67837%0.373SS*.  trans-64.3146.4177.2-65.2-179.9-179.6179.30110.5S60 L61 N62K58-S60 PolarHBondContact O-N 3.31Å; K58-S60 VanDerWaalsContact O-N 3.11Å; K58-L61 WeakPolarHBondContact O-CB 3.36Å; K58-L61 PolarHBondContact O-N 3.27Å; K58-N62 PolarHBondContact O-N 2.8Å
59H61.1Low76.8Confident134 Ų13465 Ų6562%0.6233%0.328SS*.Hα-helixtrans-50.2-40.4178.4-168.2-82000113.6L61 N62 E63H59-L61 VanDerWaalsContact C-N 3.31Å; H59-L61 PolarHBondContact O-N 3.43Å; H59-N62 WeakPolarHBondContact O-CB 3.43Å; H59-N62 PolarHBondContact O-N 2.88Å; H59-N62 VanDerWaalsContact O-N 3.1Å; H59-E63 IonicContact CE1-OE1 3.24Å; H59-E63 PolarHBondContact CE1-OE1 2.87Å; H59-E63 IonicContact ND1-OE1 3.39Å; H59-E63 PolarHBondContact O-N 3.19Å; H59-E63 VanDerWaalsContact O-N 3.17Å
60S58.3Low79Confident78 Ų7864.9 Ų64.955%0.54533%0.326SS..Hα-helixtrans-63.3-33.4178.658.80000113.6K58 E64K58-S60 PolarHBondContact O-N 3.31Å; K58-S60 VanDerWaalsContact O-N 3.11Å; S60-E64 PolarHBondContact O-N 3.4Å
61L77.4Confident80.6Confident44 Ų4462.5 Ų62.523%0.2332%0.318CS..Hα-helixtrans-74.3-32.2174.6-69.5168.8000111.3E57 K58 H59 E64 F65E57-L61 WeakPolarHBondContact OE2-CD1 3.46Å; K58-L61 WeakPolarHBondContact O-CB 3.36Å; K58-L61 PolarHBondContact O-N 3.27Å; H59-L61 VanDerWaalsContact C-N 3.31Å; H59-L61 PolarHBondContact O-N 3.43Å; L61-E64 PolarHBondContact O-N 2.89Å; L61-F65 HydrophobicContact CB-CE2 4.48Å; L61-F65 HydrophobicContact CB-CZ 4.38Å; L61-F65 HydrophobicContact CD2-CE1 4.41Å; L61-F65 HydrophobicContact CD2-CZ 4.28Å; L61-F65 WeakPolarHBondContact O-CG 3.01Å; L61-F65 PolarHBondContact O-N 3Å
62N79.7Confident82.3Confident46 Ų4659 Ų5925%0.24629%0.294CS..Hα-helixtrans-62.7-42.2175.7-75.8-31.8000112.5K58 H59 S66 W239K58-N62 PolarHBondContact O-N 2.8Å; H59-N62 WeakPolarHBondContact O-CB 3.43Å; H59-N62 PolarHBondContact O-N 2.88Å; H59-N62 VanDerWaalsContact O-N 3.1Å; N62-S66 WeakPolarHBondContact O-CB 3.2Å; N62-S66 PolarHBondContact O-N 3.42Å; N62-S66 PolarHBondContact O-OG 2.92Å; N62-W239 VanDerWaalsContact OD1-CZ2 3.3Å; N62-W239 WeakPolarHBondContact OD1-CZ2 3.35Å; N62-W239 PolarHBondContact OD1-NE1 3.39Å
63E86.6Confident83.5Confident120 Ų12058.7 Ų58.756%0.56129%0.292SS*.Hα-helixtrans-69.6-42175.4-69.4179.8165.300111.9H59 F65 S66 S67H59-E63 IonicContact CE1-OE1 3.24Å; H59-E63 PolarHBondContact CE1-OE1 2.87Å; H59-E63 IonicContact ND1-OE1 3.39Å; H59-E63 PolarHBondContact O-N 3.19Å; H59-E63 VanDerWaalsContact O-N 3.17Å; E63-F65 PolarHBondContact O-N 3.26Å; E63-S66 PolarHBondContact O-N 3.21Å; E63-S67 WeakPolarHBondContact O-CB 3.47Å; E63-S67 PolarHBondContact O-N 3.24Å
64E92.1Very high84.5Confident69 Ų6959 Ų5932%0.32230%0.298SS..Hα-helixtrans-57.3-50.5177.3-175.1-174.4161.100111.3S60 L61 S67 L68 R246S60-E64 PolarHBondContact O-N 3.4Å; L61-E64 PolarHBondContact O-N 2.89Å; E64-S67 WeakPolarHBondContact O-CB 3.3Å; E64-S67 PolarHBondContact O-N 3.27Å; E64-L68 HydrophobicContact CG-CD1 4.06Å; E64-L68 WeakPolarHBondContact O-CB 3.46Å; E64-L68 VanDerWaalsContact O-CG 3.31Å; E64-L68 WeakPolarHBondContact O-CG 3.3Å; E64-L68 PolarHBondContact O-N 3.49Å; E64-R246 VanDerWaalsContact OE1-CD 3.23Å; E64-R246 WeakPolarHBondContact OE1-CD 3.38Å; E64-R246 IonicContact OE1-NE 2.69Å; E64-R246 PolarHBondContact OE1-NE 3.46Å
65F93.7Very high85.4Confident9 Ų963.4 Ų63.44%0.03932%0.318CS..Hα-helixtrans-67.8-44.1-178-62-13.5000111.8L61 E63 S67 L68 G69 W239 G242 F243 R246L61-F65 HydrophobicContact CB-CE2 4.48Å; L61-F65 HydrophobicContact CB-CZ 4.38Å; L61-F65 HydrophobicContact CD2-CE1 4.41Å; L61-F65 HydrophobicContact CD2-CZ 4.28Å; L61-F65 WeakPolarHBondContact O-CG 3.01Å; L61-F65 PolarHBondContact O-N 3Å; E63-F65 PolarHBondContact O-N 3.26Å; F65-S67 VanDerWaalsContact C-N 3.28Å; F65-S67 PolarHBondContact O-N 2.99Å; F65-L68 PolarHBondContact O-N 2.91Å; F65-G69 PolarHBondContact O-N 2.86Å; F65-W239 HydrophobicContact CB-CD2 4.09Å; F65-W239 HydrophobicContact CB-CG 4.21Å; F65-W239 HydrophobicContact CD2-CD2 4.06Å; F65-W239 AromaticContact CD2-CE2 3.7Å; F65-W239 HydrophobicContact CD2-CE3 4.09Å; F65-W239 AromaticContact CD2-CH2 3.48Å; F65-W239 HydrophobicContact CD2-CH2 3.48Å; F65-W239 VanDerWaalsContact CD2-CH2 3.48Å; F65-W239 AromaticContact CD2-CZ2 3.45Å; F65-W239 HydrophobicContact CD2-CZ2 3.45Å; F65-W239 VanDerWaalsContact CD2-CZ2 3.45Å; F65-W239 AromaticContact CD2-CZ3 3.77Å; F65-W239 HydrophobicContact CD2-CZ3 3.77Å; F65-W239 AromaticContact CE2-CH2 3.76Å; F65-W239 HydrophobicContact CE2-CH2 3.76Å; F65-W239 AromaticContact CE2-CZ2 3.97Å; F65-W239 HydrophobicContact CE2-CZ2 3.97Å; F65-W239 HydrophobicContact CE2-CZ3 4.27Å; F65-G242 VanDerWaalsContact O-CA 3.3Å; F65-G242 WeakPolarHBondContact O-CA 3.22Å; F65-F243 HydrophobicContact CD2-CB 4.1Å; F65-F243 HydrophobicContact CE2-CB 4.44Å; F65-F243 HydrophobicContact CE2-CD2 4.11Å; F65-F243 HydrophobicContact CG-CB 4.4Å; F65-R246 HydrophobicContact CD1-CB 4.16Å; F65-R246 HydrophobicContact CE1-CB 3.72Å; F65-R246 HydrophobicContact CE1-CG 3.7Å; F65-R246 HydrophobicContact CZ-CG 4.39Å
66S93.5Very high86.6Confident46 Ų4658.2 Ų58.232%0.32230%0.298SS..Hα-helixtrans-58.1-43.8175.5-56.10000111.3N62 E63 G69 M70N62-S66 WeakPolarHBondContact O-CB 3.2Å; N62-S66 PolarHBondContact O-N 3.42Å; N62-S66 PolarHBondContact O-OG 2.92Å; E63-S66 PolarHBondContact O-N 3.21Å; S66-G69 PolarHBondContact O-N 3.46Å; S66-M70 WeakPolarHBondContact O-CB 3.43Å; S66-M70 VanDerWaalsContact O-CG 3.29Å; S66-M70 WeakPolarHBondContact O-CG 3.23Å; S66-M70 PolarHBondContact O-N 3.19Å
67S95.9Very high88Confident41 Ų4153 Ų5329%0.28728%0.276SS..Hα-helixtrans-61.5-49.6176.8177.90000112.2E63 E64 F65 G69 M70 D71 R128E63-S67 WeakPolarHBondContact O-CB 3.47Å; E63-S67 PolarHBondContact O-N 3.24Å; E64-S67 WeakPolarHBondContact O-CB 3.3Å; E64-S67 PolarHBondContact O-N 3.27Å; F65-S67 VanDerWaalsContact C-N 3.28Å; F65-S67 PolarHBondContact O-N 2.99Å; S67-G69 VanDerWaalsContact C-N 3.31Å; S67-G69 PolarHBondContact O-N 3.03Å; S67-M70 PolarHBondContact O-N 3.33Å; S67-D71 WeakPolarHBondContact O-CB 3.32Å; S67-D71 PolarHBondContact O-N 2.76Å; S67-R128 PolarHBondContact O-NH1 3.32Å; S67-R128 PolarHBondContact OG-NH2 3.23Å
68L97Very high89.4Confident39 Ų3950.3 Ų50.320%0.20426%0.264CS..Hα-helixtrans-62.2-37.9177.5-72173.6000112E64 F65 A72 R245 R246E64-L68 HydrophobicContact CG-CD1 4.06Å; E64-L68 WeakPolarHBondContact O-CB 3.46Å; E64-L68 VanDerWaalsContact O-CG 3.31Å; E64-L68 WeakPolarHBondContact O-CG 3.3Å; E64-L68 PolarHBondContact O-N 3.49Å; F65-L68 PolarHBondContact O-N 2.91Å; L68-A72 PolarHBondContact O-N 3.16Å; L68-R245 PolarHBondContact O-NH1 3Å; L68-R246 HydrophobicContact CD1-CB 4.45Å
69G97.6Very high91Very high0 Ų042.9 Ų42.90%023%0.231CC..Hα-helixtrans-63.4-52.3174.200000112.9F65 S66 S67 D71 A72 I73 P238F65-G69 PolarHBondContact O-N 2.86Å; S66-G69 PolarHBondContact O-N 3.46Å; S67-G69 VanDerWaalsContact C-N 3.31Å; S67-G69 PolarHBondContact O-N 3.03Å; G69-D71 VanDerWaalsContact C-N 3.26Å; G69-D71 PolarHBondContact O-N 3.09Å; G69-A72 WeakPolarHBondContact O-CB 3.28Å; G69-A72 PolarHBondContact O-N 3.16Å; G69-I73 PolarHBondContact O-N 3.14Å; G69-P238 WeakPolarHBondContact CA-O 3.46Å
70M97.3Very high92.8Very high17 Ų1736.5 Ų36.58%0.08420%0.202CC..Hα-helixtrans-61.5-36.5-179.8-74-58.3-66.500111.8S66 S67 A72 I73 A74 L121 M124 A125 R128 P238S66-M70 WeakPolarHBondContact O-CB 3.43Å; S66-M70 VanDerWaalsContact O-CG 3.29Å; S66-M70 WeakPolarHBondContact O-CG 3.23Å; S66-M70 PolarHBondContact O-N 3.19Å; S67-M70 PolarHBondContact O-N 3.33Å; M70-A72 VanDerWaalsContact C-N 3.33Å; M70-A72 PolarHBondContact O-N 3.09Å; M70-I73 PolarHBondContact O-N 3.24Å; M70-I73 HydrophobicContact SD-CD1 4.2Å; M70-A74 WeakPolarHBondContact O-CB 3.29Å; M70-A74 PolarHBondContact O-N 3.34Å; M70-L121 HydrophobicContact SD-CD2 4.33Å; M70-M124 HydrophobicContact CE-CB 3.87Å; M70-A125 HydrophobicContact CE-CB 3.76Å; M70-R128 VanDerWaalsContact CB-NH1 3.27Å; M70-P238 HydrophobicContact CG-CB 3.88Å; M70-P238 HydrophobicContact CG-CG 4.16Å; M70-P238 HydrophobicContact SD-CB 3.9Å; M70-P238 HydrophobicContact SD-CG 3.51Å; M70-P238 VanDerWaalsContact SD-CG 3.51Å
71D97.2Very high94.7Very high50 Ų5032.8 Ų32.827%0.26718%0.176SC..Hα-helixtrans-60.7-40.3172.6-84.922.4000112.6S67 G69 K75 R128S67-D71 WeakPolarHBondContact O-CB 3.32Å; S67-D71 PolarHBondContact O-N 2.76Å; G69-D71 VanDerWaalsContact C-N 3.26Å; G69-D71 PolarHBondContact O-N 3.09Å; D71-K75 WeakPolarHBondContact O-CB 3.5Å; D71-K75 WeakPolarHBondContact O-CD 3.25Å; D71-K75 VanDerWaalsContact O-CG 3.23Å; D71-K75 WeakPolarHBondContact O-CG 3.47Å; D71-K75 PolarHBondContact O-N 2.99Å; D71-R128 IonicContact OD1-CZ 3.44Å; D71-R128 IonicContact OD1-NH1 2.86Å; D71-R128 PolarHBondContact OD1-NH1 2.94Å; D71-R128 IonicContact OD1-NH2 3.25Å
72A97.9Very high95.8Very high0 Ų030.7 Ų30.70%017%0.165CC..Hα-helixtrans-69.4-39178.500000111.2L68 G69 M70 K75 G76 Q77 V78 Y222 I241L68-A72 PolarHBondContact O-N 3.16Å; G69-A72 WeakPolarHBondContact O-CB 3.28Å; G69-A72 PolarHBondContact O-N 3.16Å; M70-A72 VanDerWaalsContact C-N 3.33Å; M70-A72 PolarHBondContact O-N 3.09Å; A72-K75 PolarHBondContact O-N 3.45Å; A72-G76 PolarHBondContact O-N 2.83Å; A72-Q77 WeakPolarHBondContact O-CB 3.46Å; A72-Q77 PolarHBondContact O-N 2.84Å; A72-V78 HydrophobicContact CB-CG2 3.84Å; A72-Y222 HydrophobicContact CB-CD2 4.04Å; A72-Y222 HydrophobicContact CB-CE2 4.11Å; A72-I241 HydrophobicContact CB-CG2 3.98Å
73I98.1Very high96.6Very high2 Ų229.1 Ų29.11%0.0116%0.156CC..Hα-helixtrans-62.5-50.3173.5-64.9172.2000110.1G69 M70 K75 G76 V78 L121 A125 I136 P238 I241G69-I73 PolarHBondContact O-N 3.14Å; M70-I73 PolarHBondContact O-N 3.24Å; M70-I73 HydrophobicContact SD-CD1 4.2Å; I73-K75 PolarHBondContact O-N 3.01Å; I73-G76 PolarHBondContact O-N 3.04Å; I73-V78 HydrophobicContact CG1-CB 4.12Å; I73-V78 HydrophobicContact CG1-CG1 4.39Å; I73-V78 HydrophobicContact CG1-CG2 3.83Å; I73-L121 HydrophobicContact CD1-CD1 4.4Å; I73-L121 HydrophobicContact CD1-CD2 4.46Å; I73-A125 HydrophobicContact CB-CB 4.47Å; I73-A125 HydrophobicContact CG2-CB 3.74Å; I73-I136 HydrophobicContact CG2-CD1 3.94Å; I73-I136 HydrophobicContact CG2-CG1 4.11Å; I73-P238 HydrophobicContact CD1-CB 4.37Å; I73-P238 HydrophobicContact CD1-CG 3.82Å; I73-I241 HydrophobicContact CD1-CD1 4.5Å; I73-I241 HydrophobicContact CG1-CD1 4.46Å
74A97.5Very high97Very high30 Ų3023.5 Ų23.525%0.24813%0.13CC..Hα-helixtrans-61.4-32.4-178.900000113M70 G76 A125 V133M70-A74 WeakPolarHBondContact O-CB 3.29Å; M70-A74 PolarHBondContact O-N 3.34Å; A74-G76 PolarHBondContact O-N 2.89Å; A74-A125 HydrophobicContact CB-CB 4.38Å; A74-V133 HydrophobicContact CB-CG1 3.97Å
75K97Very high96.6Very high129 Ų12920.6 Ų20.656%0.56112%0.118SC*.THydrogen-bonded Turntrans-79.33.3174.3-70.5170.5-176.3169.30113.9D71 A72 I73 Q77D71-K75 WeakPolarHBondContact O-CB 3.5Å; D71-K75 WeakPolarHBondContact O-CD 3.25Å; D71-K75 VanDerWaalsContact O-CG 3.23Å; D71-K75 WeakPolarHBondContact O-CG 3.47Å; D71-K75 PolarHBondContact O-N 2.99Å; A72-K75 PolarHBondContact O-N 3.45Å; I73-K75 PolarHBondContact O-N 3.01Å; K75-Q77 VanDerWaalsContact C-N 3.3Å; K75-Q77 HydrophobicContact CB-CG 3.87Å; K75-Q77 PolarHBondContact O-N 2.79Å
76G97.5Very high96Very high15 Ų1522.3 Ų22.316%0.15514%0.139CC..THydrogen-bonded Turntrans66.328.3-178.900000113.7A72 I73 A74 I220A72-G76 PolarHBondContact O-N 2.83Å; I73-G76 PolarHBondContact O-N 3.04Å; A74-G76 PolarHBondContact O-N 2.89Å; G76-I220 WeakPolarHBondContact O-CD1 3.13Å
77Q98.5Very high95.4Very high29 Ų2923.6 Ų23.614%0.13614%0.14CC..  trans-97.44.4-173.7-62.1-178.2-24.200113.7A72 K75 R221 Y222A72-Q77 WeakPolarHBondContact O-CB 3.46Å; A72-Q77 PolarHBondContact O-N 2.84Å; K75-Q77 VanDerWaalsContact C-N 3.3Å; K75-Q77 HydrophobicContact CB-CG 3.87Å; K75-Q77 PolarHBondContact O-N 2.79Å; Q77-R221 HydrophobicContact CB-CB 4.24Å; Q77-R221 HydrophobicContact CB-CG 4.27Å; Q77-R221 HydrophobicContact CG-CG 4.38Å; Q77-R221 PolarHBondContact O-N 2.74Å; Q77-Y222 HydrophobicContact CB-CD2 4.48Å; Q77-Y222 PolarHBondContact O-N 3.36Å
78V98.7Very high94.6Very high3 Ų321.7 Ų21.72%0.01813%0.127CC..EExtended strand (participates in β ladder)trans-118.3130.3-171.3179.70000110.3A72 I73 Y222 A236 I241A72-V78 HydrophobicContact CB-CG2 3.84Å; I73-V78 HydrophobicContact CG1-CB 4.12Å; I73-V78 HydrophobicContact CG1-CG1 4.39Å; I73-V78 HydrophobicContact CG1-CG2 3.83Å; V78-Y222 WeakPolarHBondContact CA-O 3.4Å; V78-A236 HydrophobicContact CG1-CB 4.27Å; V78-I241 HydrophobicContact CB-CD1 4.47Å; V78-I241 HydrophobicContact CG1-CD1 3.67Å; V78-I241 HydrophobicContact CG2-CD1 3.94Å; V78-I241 HydrophobicContact CG2-CG2 4.37Å
79A98.9Very high93.8Very high0 Ų024.6 Ų24.60%015%0.146CC..EExtended strand (participates in β ladder)trans-125.2162.3167.400000109.8T137 L215 I220 Y222 V223 H224A79-T137 CarbonylContact C-O 3.56Å; A79-T137 VanDerWaalsContact CA-O 3.29Å; A79-T137 WeakPolarHBondContact CA-O 3.37Å; A79-T137 WeakPolarHBondContact CB-O 3.42Å; A79-L215 HydrophobicContact CB-CD2 3.68Å; A79-I220 HydrophobicContact CB-CD1 4.04Å; A79-I220 HydrophobicContact CB-CG1 4.14Å; A79-I220 HydrophobicContact CB-CG2 3.72Å; A79-Y222 PolarHBondContact N-O 3.46Å; A79-V223 WeakPolarHBondContact O-CA 3.46Å; A79-H224 PolarHBondContact O-N 3.36Å
80V98.8Very high92.9Very high0 Ų032.6 Ų32.60%018%0.177CC..EExtended strand (participates in β ladder)trans-123.7144172.8-61.10000110.8L118 I136 T137 W138 C139 H224 Y226 V235 A236V80-L118 HydrophobicContact CG1-CD2 4.4Å; V80-L118 HydrophobicContact CG2-CD1 4.14Å; V80-L118 HydrophobicContact CG2-CD2 4.13Å; V80-I136 HydrophobicContact CG1-CG2 4.32Å; V80-I136 HydrophobicContact CG2-CG2 4.48Å; V80-T137 PolarHBondContact N-O 2.55Å; V80-W138 HydrophobicContact CG2-CB 4.03Å; V80-W138 VanDerWaalsContact CG2-CD1 3.48Å; V80-W138 HydrophobicContact CG2-CG 3.8Å; V80-C139 PolarHBondContact O-N 2.83Å; V80-H224 CarbonylContact C-O 3.5Å; V80-H224 WeakPolarHBondContact CA-O 3.41Å; V80-H224 HydrophobicContact CG1-CB 4.22Å; V80-Y226 HydrophobicContact CB-CE1 4.12Å; V80-V235 HydrophobicContact CB-CG1 4.3Å; V80-V235 HydrophobicContact CG1-CG1 3.94Å; V80-V235 HydrophobicContact CG2-CG1 4.14Å; V80-A236 HydrophobicContact CG1-CB 3.6Å
81I98.8Very high92.1Very high0 Ų032.5 Ų32.50%018%0.176CC..EExtended strand (participates in β ladder)trans-116.4122.2171.1-60.2169.9000108.8L83 C139 F170 L202 L206 V223 H224 V225 Y226 L314I81-L83 HydrophobicContact CG2-CD2 4.28Å; I81-C139 CarbonylContact C-O 3.52Å; I81-C139 VanDerWaalsContact CA-O 3.26Å; I81-C139 WeakPolarHBondContact CA-O 3.35Å; I81-C139 HydrophobicContact CG1-CB 3.93Å; I81-F170 HydrophobicContact CG2-CE1 4.22Å; I81-F170 HydrophobicContact CG2-CZ 3.94Å; I81-L202 HydrophobicContact CD1-CD1 4.3Å; I81-L202 HydrophobicContact CG2-CD1 3.81Å; I81-L206 HydrophobicContact CD1-CD1 3.96Å; I81-L206 HydrophobicContact CD1-CD2 3.85Å; I81-L206 HydrophobicContact CD1-CG 4.47Å; I81-V223 HydrophobicContact CD1-CG1 3.38Å; I81-V223 HydrophobicContact CG1-CG1 3.58Å; I81-H224 PolarHBondContact N-O 3.26Å; I81-V225 HydrophobicContact CB-CB 4.35Å; I81-V225 HydrophobicContact CB-CG1 4Å; I81-V225 HydrophobicContact CB-CG2 4Å; I81-V225 HydrophobicContact CD1-CG2 4.01Å; I81-V225 HydrophobicContact CG1-CG2 4.37Å; I81-V225 HydrophobicContact CG2-CG1 4.11Å; I81-V225 WeakPolarHBondContact O-CA 3.48Å; I81-Y226 WeakPolarHBondContact O-CD1 3.48Å; I81-Y226 PolarHBondContact O-N 2.83Å; I81-L314 HydrophobicContact CD1-CD1 4.48Å
82L98.7Very high91.3Very high0 Ų033.7 Ų33.70%020%0.201CC..EExtended strand (participates in β ladder)trans-97.4121.7174176.155.8000110.9S84 F111 W138 C139 I140 M141 Y226 V228L82-S84 PolarHBondContact O-N 3.29Å; L82-F111 HydrophobicContact CD2-CD1 3.78Å; L82-F111 HydrophobicContact CD2-CE1 3.5Å; L82-W138 HydrophobicContact CD2-CZ2 3.73Å; L82-C139 PolarHBondContact N-O 2.8Å; L82-I140 HydrophobicContact CB-CG1 4.33Å; L82-I140 HydrophobicContact CD2-CD1 4.47Å; L82-I140 HydrophobicContact CD2-CG1 4.44Å; L82-I140 HydrophobicContact CD2-CG2 4.44Å; L82-M141 PolarHBondContact O-N 3.31Å; L82-Y226 HydrophobicContact CB-CE1 4.34Å; L82-Y226 HydrophobicContact CD1-CD2 4.04Å; L82-Y226 HydrophobicContact CD1-CE1 4.48Å; L82-Y226 HydrophobicContact CD1-CE2 3.53Å; L82-V228 VanDerWaalsContact CD1-CA 3.45Å; L82-V228 HydrophobicContact CD1-CB 3.57Å; L82-V228 HydrophobicContact CD1-CG2 4.09Å; L82-V228 HydrophobicContact CD2-CG2 4.27Å; L82-V228 HydrophobicContact CG-CB 4.32Å
83L97.6Very high90.6Very high13 Ų1335.4 Ų35.47%0.06821%0.212CC..EExtended strand (participates in β ladder)trans-83.899.8173.4-49.1173.1000109I81 M141 N199 L202 V225 Y226 V228 I357I81-L83 HydrophobicContact CG2-CD2 4.28Å; L83-M141 HydrophobicContact CB-CE 4.46Å; L83-M141 HydrophobicContact CD2-CE 3.58Å; L83-M141 HydrophobicContact CD2-SD 4.28Å; L83-N199 HydrophobicContact CD1-CB 4.18Å; L83-L202 HydrophobicContact CD2-CD1 4.22Å; L83-L202 HydrophobicContact CD2-CD2 4.21Å; L83-V225 HydrophobicContact CD1-CG1 4.04Å; L83-V225 HydrophobicContact CD2-CG1 3.8Å; L83-V225 HydrophobicContact CG-CG1 3.94Å; L83-Y226 WeakPolarHBondContact CG-O 3.31Å; L83-Y226 PolarHBondContact N-O 3.26Å; L83-V228 PolarHBondContact O-N 3.38Å; L83-I357 HydrophobicContact CD1-CD1 3.58Å; L83-I357 HydrophobicContact CD2-CD1 4.37Å
84S94.5Very high89.9Confident1 Ų138.8 Ų38.81%0.00724%0.24CC..  trans-129.131-176-171.20000113.1L82 G86 F111 M141 T146L82-S84 PolarHBondContact O-N 3.29Å; S84-G86 VanDerWaalsContact C-N 3.31Å; S84-G86 PolarHBondContact O-N 2.91Å; S84-F111 WeakPolarHBondContact OG-CZ 3.47Å; S84-M141 CarbonylContact C-O 3.34Å; S84-M141 VanDerWaalsContact CA-O 3.29Å; S84-M141 WeakPolarHBondContact CA-O 3.43Å; S84-M141 PolarHBondContact N-O 2.89Å; S84-T146 PolarHBondContact O-OG1 3.46Å
85G83.8Confident89.6Confident8 Ų841.6 Ų41.68%0.08225%0.249CC..  trans-73-19.1179.400000115M141 S143G85-M141 PolarHBondContact N-O 3.44Å; G85-S143 WeakPolarHBondContact O-CB 3.32Å; G85-S143 PolarHBondContact O-OG 2.88Å
86G81.9Confident89.3Confident46 Ų4635.7 Ų35.747%0.47422%0.223SC..SBendtrans-93.4151.3-174.900000115S84S84-G86 VanDerWaalsContact C-N 3.31Å; S84-G86 PolarHBondContact O-N 2.91Å
87Q81.3Confident89.1Confident73 Ų7336.3 Ų36.334%0.34122%0.222SC..BIsolated β-bridgetrans-87158.3170.6-67.5172.6-5900111.8T89 A94 T146Q87-T89 PolarHBondContact O-N 3.32Å; Q87-A94 PolarHBondContact NE2-O 3.01Å; Q87-T146 HydrophobicContact CG-CG2 3.97Å
88G78.8Confident89Confident1 Ų135 Ų351%0.0122%0.215CC..  trans-75.231.117500000114.8R90 L91 G92 S93 E95G88-R90 VanDerWaalsContact C-N 3.31Å; G88-R90 PolarHBondContact O-N 3.29Å; G88-L91 CarbonylContact O-C 3.11Å; G88-L91 VanDerWaalsContact O-CA 3.32Å; G88-L91 WeakPolarHBondContact O-CA 3.15Å; G88-L91 VanDerWaalsContact O-CB 3.25Å; G88-L91 WeakPolarHBondContact O-CB 3.36Å; G88-L91 PolarHBondContact O-N 3.22Å; G88-G92 PolarHBondContact O-N 3.45Å; G88-S93 CarbonylContact C-O 3.59Å; G88-S93 PolarHBondContact O-N 3.08Å; G88-S93 VanDerWaalsContact O-N 3.13Å; G88-E95 PolarHBondContact N-O 2.8Å
89T78.7Confident88.8Confident99 Ų9936.6 Ų36.661%0.60722%0.222SC*.G310 helixtrans-59.3-38.8-167.7-430000113.1Q87 L91 G92 S93Q87-T89 PolarHBondContact O-N 3.32Å; T89-L91 PolarHBondContact O-N 3.11Å; T89-G92 PolarHBondContact O-N 2.93Å; T89-S93 VanDerWaalsContact CA-O 3.3Å; T89-S93 WeakPolarHBondContact CA-O 3.47Å; T89-S93 PolarHBondContact N-O 3.11Å; T89-S93 VanDerWaalsContact N-O 3.13Å
90R78.7Confident88.6Confident169 Ų16939.2 Ų39.264%0.63823%0.233SC*.G310 helixtrans-68.1-19.3175.2-68.7-174-176.8-179.62.8113.7G88 G92 K382 A384G88-R90 VanDerWaalsContact C-N 3.31Å; G88-R90 PolarHBondContact O-N 3.29Å; R90-G92 VanDerWaalsContact C-N 3.28Å; R90-K382 WeakPolarHBondContact CB-O 3.4Å; R90-A384 PolarHBondContact O-N 3.13Å
91L81Confident88.4Confident14 Ų1442.6 Ų42.67%0.07325%0.251CS..G310 helixtrans-89.13.1174.1-52.5172.3000111.7G88 T89 K97 Y100 L381 N383G88-L91 CarbonylContact O-C 3.11Å; G88-L91 VanDerWaalsContact O-CA 3.32Å; G88-L91 WeakPolarHBondContact O-CA 3.15Å; G88-L91 VanDerWaalsContact O-CB 3.25Å; G88-L91 WeakPolarHBondContact O-CB 3.36Å; G88-L91 PolarHBondContact O-N 3.22Å; T89-L91 PolarHBondContact O-N 3.11Å; L91-K97 HydrophobicContact CD1-CD 4.31Å; L91-K97 HydrophobicContact CD1-CG 3.89Å; L91-Y100 HydrophobicContact CB-CD2 4.16Å; L91-Y100 HydrophobicContact CB-CE2 3.61Å; L91-Y100 HydrophobicContact CD1-CD2 3.57Å; L91-Y100 HydrophobicContact CD1-CE2 3.78Å; L91-Y100 HydrophobicContact CD1-CG 4Å; L91-Y100 HydrophobicContact CG-CD2 4.47Å; L91-Y100 HydrophobicContact CG-CE2 4.23Å; L91-L381 HydrophobicContact CD1-CD2 3.77Å; L91-L381 HydrophobicContact CD1-CG 3.88Å; L91-L381 HydrophobicContact CD2-CD1 3.94Å; L91-L381 HydrophobicContact CD2-CG 3.98Å; L91-N383 VanDerWaalsContact CD2-C 3.46Å; L91-N383 WeakPolarHBondContact CD2-O 3.44Å
92G80.3Confident88.2Confident76 Ų7642.8 Ų42.878%0.78425%0.252SS*.THydrogen-bonded Turntrans77.718.6-175.600000114.1G88 T89 R90G88-G92 PolarHBondContact O-N 3.45Å; T89-G92 PolarHBondContact O-N 2.93Å; R90-G92 VanDerWaalsContact C-N 3.28Å
93S83.1Confident88.1Confident35 Ų3544.8 Ų44.825%0.24527%0.272CS..  trans-119.2137.6-179.1-176.50000112.3G88 T89 E95G88-S93 CarbonylContact C-O 3.59Å; G88-S93 PolarHBondContact O-N 3.08Å; G88-S93 VanDerWaalsContact O-N 3.13Å; T89-S93 VanDerWaalsContact CA-O 3.3Å; T89-S93 WeakPolarHBondContact CA-O 3.47Å; T89-S93 PolarHBondContact N-O 3.11Å; T89-S93 VanDerWaalsContact N-O 3.13Å; S93-E95 VanDerWaalsContact C-N 3.28Å; S93-E95 WeakPolarHBondContact OG-CB 3.29Å; S93-E95 PolarHBondContact OG-N 2.68Å
94A83.6Confident88.1Confident73 Ų7344.6 Ų44.660%0.60327%0.271SS*.SBendtrans-81.1-11.4168.900000112.4Q87Q87-A94 PolarHBondContact NE2-O 3.01Å
95E90.9Very high88.2Confident90 Ų9047.5 Ų47.542%0.42129%0.29SS..SBendtrans-76157.9-177.9-65-60.4132.900112.2G88 S93 K97 F99G88-E95 PolarHBondContact N-O 2.8Å; S93-E95 VanDerWaalsContact C-N 3.28Å; S93-E95 WeakPolarHBondContact OG-CB 3.29Å; S93-E95 PolarHBondContact OG-N 2.68Å; E95-K97 PolarHBondContact O-N 3.34Å; E95-F99 HydrophobicContact CB-CD2 3.9Å; E95-F99 HydrophobicContact CB-CE2 4.49Å; E95-F99 HydrophobicContact CG-CD2 4.22Å; E95-F99 WeakPolarHBondContact OE2-CD2 3.35Å; E95-F99 WeakPolarHBondContact OE2-CE2 3.11Å
96P92.3Very high88.8Confident4 Ų448.9 Ų48.93%0.02630%0.299CS..BIsolated β-bridgetrans-53135.9167.9-22.732.8000110.9G98 F99 T146 S149 V150P96-G98 PolarHBondContact O-N 3.33Å; P96-G98 VanDerWaalsContact O-N 3.1Å; P96-F99 HydrophobicContact CB-CD1 4.23Å; P96-F99 HydrophobicContact CB-CE1 4.08Å; P96-F99 HydrophobicContact CB-CZ 4.37Å; P96-F99 HydrophobicContact CG-CE1 4.01Å; P96-F99 HydrophobicContact CG-CE2 4.19Å; P96-F99 HydrophobicContact CG-CZ 3.81Å; P96-F99 WeakPolarHBondContact O-CB 3.29Å; P96-F99 PolarHBondContact O-N 3.26Å; P96-T146 HydrophobicContact CB-CG2 4.28Å; P96-T146 HydrophobicContact CG-CG2 4.06Å; P96-S149 WeakPolarHBondContact CG-OG 3.49Å; P96-V150 HydrophobicContact CB-CG2 3.65Å; P96-V150 HydrophobicContact CG-CG2 3.63Å
97K93.2Very high89.5Confident29 Ų2948.3 Ų48.313%0.12629%0.292CS..G310 helixtrans-60.5-28.3-174.9-168.5-174.2-76.8-168.80113.2L91 E95 F99 Y100 V228 D229 L381L91-K97 HydrophobicContact CD1-CD 4.31Å; L91-K97 HydrophobicContact CD1-CG 3.89Å; E95-K97 PolarHBondContact O-N 3.34Å; K97-F99 PolarHBondContact O-N 2.86Å; K97-F99 VanDerWaalsContact O-N 3.16Å; K97-Y100 WeakPolarHBondContact O-CB 3.2Å; K97-Y100 PolarHBondContact O-N 3.04Å; K97-V228 HydrophobicContact CB-CG1 4.18Å; K97-V228 HydrophobicContact CD-CG1 4.4Å; K97-D229 HydrophobicContact CD-CB 3.48Å; K97-D229 VanDerWaalsContact CD-CB 3.48Å; K97-D229 IonicContact NZ-OD2 3.26Å; K97-D229 PolarHBondContact NZ-OD2 2.98Å; K97-L381 PolarHBondContact NZ-O 3.14Å
98G95.6Very high90.3Very high0 Ų045.2 Ų45.20%028%0.278CS..G310 helixtrans-63-17.5177.600000115P96 Y100 L110 F111P96-G98 PolarHBondContact O-N 3.33Å; P96-G98 VanDerWaalsContact O-N 3.1Å; G98-Y100 PolarHBondContact O-N 3.19Å; G98-L110 PolarHBondContact O-N 2.92Å; G98-F111 VanDerWaalsContact CA-CE2 3.49Å; G98-F111 WeakPolarHBondContact O-CD2 3.27Å; G98-F111 PolarHBondContact O-N 2.86Å
99F94Very high91.2Very high38 Ų3845.4 Ų45.417%0.16728%0.279CS..G310 helixtrans-74.3-18174.7-66.99.9000112E95 P96 K97 N101 F111 S149 V150 F153E95-F99 HydrophobicContact CB-CD2 3.9Å; E95-F99 HydrophobicContact CB-CE2 4.49Å; E95-F99 HydrophobicContact CG-CD2 4.22Å; E95-F99 WeakPolarHBondContact OE2-CD2 3.35Å; E95-F99 WeakPolarHBondContact OE2-CE2 3.11Å; P96-F99 HydrophobicContact CB-CD1 4.23Å; P96-F99 HydrophobicContact CB-CE1 4.08Å; P96-F99 HydrophobicContact CB-CZ 4.37Å; P96-F99 HydrophobicContact CG-CE1 4.01Å; P96-F99 HydrophobicContact CG-CE2 4.19Å; P96-F99 HydrophobicContact CG-CZ 3.81Å; P96-F99 WeakPolarHBondContact O-CB 3.29Å; P96-F99 PolarHBondContact O-N 3.26Å; K97-F99 PolarHBondContact O-N 2.86Å; K97-F99 VanDerWaalsContact O-N 3.16Å; F99-N101 PolarHBondContact O-N 3.05Å; F99-F111 AromaticContact CD1-CD2 3.77Å; F99-F111 HydrophobicContact CD1-CD2 3.77Å; F99-F111 AromaticContact CD1-CE2 3.54Å; F99-F111 HydrophobicContact CD1-CE2 3.54Å; F99-F111 HydrophobicContact CE1-CD2 4.13Å; F99-F111 AromaticContact CE1-CE2 3.66Å; F99-F111 HydrophobicContact CE1-CE2 3.66Å; F99-S149 WeakPolarHBondContact CZ-O 3.28Å; F99-V150 HydrophobicContact CE1-CG2 4.26Å; F99-F153 HydrophobicContact CB-CE2 4.43Å; F99-F153 HydrophobicContact CB-CZ 4.44Å; F99-F153 HydrophobicContact CD1-CB 4.13Å; F99-F153 AromaticContact CD1-CD1 3.62Å; F99-F153 HydrophobicContact CD1-CD1 3.62Å; F99-F153 AromaticContact CD1-CD2 3.87Å; F99-F153 HydrophobicContact CD1-CD2 3.87Å; F99-F153 AromaticContact CD1-CE1 3.87Å; F99-F153 HydrophobicContact CD1-CE1 3.87Å; F99-F153 HydrophobicContact CD1-CE2 4.14Å; F99-F153 AromaticContact CD1-CG 3.61Å; F99-F153 HydrophobicContact CD1-CG 3.61Å; F99-F153 HydrophobicContact CD1-CZ 4.14Å; F99-F153 HydrophobicContact CD2-CD2 4.01Å; F99-F153 HydrophobicContact CD2-CE2 4.3Å; F99-F153 HydrophobicContact CD2-CG 4.45Å; F99-F153 HydrophobicContact CE1-CB 3.3Å; F99-F153 AromaticContact CE1-CD1 3.59Å; F99-F153 HydrophobicContact CE1-CD1 3.59Å; F99-F153 AromaticContact CE1-CD2 3.86Å; F99-F153 HydrophobicContact CE1-CD2 3.86Å; F99-F153 HydrophobicContact CE1-CE1 4.31Å; F99-F153 AromaticContact CE1-CG 3.31Å; F99-F153 HydrophobicContact CE1-CG 3.31Å; F99-F153 HydrophobicContact CE2-CB 4.11Å; F99-F153 AromaticContact CE2-CD2 3.95Å; F99-F153 HydrophobicContact CE2-CD2 3.95Å; F99-F153 HydrophobicContact CE2-CG 4.17Å; F99-F153 HydrophobicContact CG-CD1 4.46Å; F99-F153 AromaticContact CG-CD2 4Å; F99-F153 HydrophobicContact CG-CD2 4Å; F99-F153 HydrophobicContact CG-CE1 4.47Å; F99-F153 HydrophobicContact CG-CE2 4.04Å; F99-F153 HydrophobicContact CG-CG 4.22Å; F99-F153 HydrophobicContact CG-CZ 4.29Å; F99-F153 HydrophobicContact CZ-CB 3.31Å; F99-F153 HydrophobicContact CZ-CD1 4.38Å; F99-F153 AromaticContact CZ-CD2 3.91Å; F99-F153 HydrophobicContact CZ-CD2 3.91Å; F99-F153 AromaticContact CZ-CG 3.64Å; F99-F153 HydrophobicContact CZ-CG 3.64Å
100Y94.7Very high92.1Very high55 Ų5540.8 Ų40.822%0.21625%0.251CS..  trans-63.3126.8-168-154.8-83.3000110.9L91 K97 G98 V102 L110 L381 P392L91-Y100 HydrophobicContact CB-CD2 4.16Å; L91-Y100 HydrophobicContact CB-CE2 3.61Å; L91-Y100 HydrophobicContact CD1-CD2 3.57Å; L91-Y100 HydrophobicContact CD1-CE2 3.78Å; L91-Y100 HydrophobicContact CD1-CG 4Å; L91-Y100 HydrophobicContact CG-CD2 4.47Å; L91-Y100 HydrophobicContact CG-CE2 4.23Å; K97-Y100 WeakPolarHBondContact O-CB 3.2Å; K97-Y100 PolarHBondContact O-N 3.04Å; G98-Y100 PolarHBondContact O-N 3.19Å; Y100-V102 HydrophobicContact CD1-CG1 3.96Å; Y100-V102 HydrophobicContact CE1-CG1 4.33Å; Y100-L110 PolarHBondContact O-N 3.43Å; Y100-L381 HydrophobicContact CD1-CD2 3.6Å; Y100-L381 HydrophobicContact CE1-CD2 4.22Å; Y100-L381 HydrophobicContact CG-CD2 3.87Å; Y100-P392 HydrophobicContact CE1-CB 4.12Å; Y100-P392 HydrophobicContact CE1-CG 3.61Å; Y100-P392 VanDerWaalsContact OH-CG 3.28Å; Y100-P392 WeakPolarHBondContact OH-CG 3.38Å
101N94.8Very high93Very high71 Ų7132.8 Ų32.838%0.3822%0.22SC..BIsolated β-bridgetrans-99117.7169.7172.1-0.7000107.5F99 G103 G107F99-N101 PolarHBondContact O-N 3.05Å; N101-G103 PolarHBondContact O-N 3.36Å; N101-G103 WeakPolarHBondContact OD1-CA 3.41Å; N101-G103 PolarHBondContact OD1-N 2.79Å; N101-G107 VanDerWaalsContact CG-O 3.3Å; N101-G107 VanDerWaalsContact ND2-CA 3.32Å; N101-G107 WeakPolarHBondContact ND2-CA 3.37Å; N101-G107 PolarHBondContact ND2-O 3.42Å
102V95.6Very high93.9Very high4 Ų434.3 Ų34.32%0.02423%0.227CC..  trans-81.410.2-179.3-58.30000113.3Y100 L104 I231 L381 P392 C395 R396Y100-V102 HydrophobicContact CD1-CG1 3.96Å; Y100-V102 HydrophobicContact CE1-CG1 4.33Å; V102-L104 HydrophobicContact CG2-CD1 4.38Å; V102-L104 HydrophobicContact CG2-CD2 3.93Å; V102-L104 HydrophobicContact CG2-CG 3.77Å; V102-I231 HydrophobicContact CG1-CD1 4.36Å; V102-I231 HydrophobicContact CG2-CD1 3.5Å; V102-I231 VanDerWaalsContact CG2-CD1 3.5Å; V102-L381 HydrophobicContact CG1-CD1 4.36Å; V102-L381 HydrophobicContact CG1-CD2 3.96Å; V102-P392 HydrophobicContact CB-CB 4.33Å; V102-C395 HydrophobicContact CG1-CB 4.37Å; V102-R396 HydrophobicContact CG2-CB 4.44Å; V102-R396 PolarHBondContact O-NH1 2.78Å
103G96.3Very high94.7Very high41 Ų4131 Ų3142%0.42319%0.191SC..  trans8036.3-179.500000113.8N101 R396N101-G103 PolarHBondContact O-N 3.36Å; N101-G103 WeakPolarHBondContact OD1-CA 3.41Å; N101-G103 PolarHBondContact OD1-N 2.79Å; G103-R396 WeakPolarHBondContact O-CD 3.28Å
104L97.5Very high95.5Very high9 Ų929.4 Ų29.45%0.04718%0.18CC..  trans-69.2154.1169.6-58.7179.6000110.4V102 S106 G107 L113 R396 L399 Y400V102-L104 HydrophobicContact CG2-CD1 4.38Å; V102-L104 HydrophobicContact CG2-CD2 3.93Å; V102-L104 HydrophobicContact CG2-CG 3.77Å; L104-S106 PolarHBondContact O-N 2.7Å; L104-G107 PolarHBondContact O-N 2.98Å; L104-L113 HydrophobicContact CD1-CD1 3.93Å; L104-L113 HydrophobicContact CD1-CD2 4.17Å; L104-R396 HydrophobicContact CD2-CB 4.47Å; L104-R396 HydrophobicContact CD2-CG 4Å; L104-L399 HydrophobicContact CD1-CD2 3.55Å; L104-L399 HydrophobicContact CD2-CD2 3.64Å; L104-L399 HydrophobicContact CG-CD2 4.26Å; L104-Y400 HydrophobicContact CD2-CE1 3.84Å
105P97Very high96.2Very high62 Ų6225.9 Ų25.940%0.40315%0.151SC..THydrogen-bonded Turntrans-54.1-35.1175.5-27.334.3000113.4G107 Y400 V423 E425 V450P105-G107 VanDerWaalsContact C-N 3.3Å; P105-G107 PolarHBondContact O-N 2.87Å; P105-Y400 WeakPolarHBondContact CD-OH 3.33Å; P105-V423 HydrophobicContact CG-CG1 3.75Å; P105-E425 WeakPolarHBondContact CB-OE2 3.32Å; P105-E425 WeakPolarHBondContact CD-OE2 3.44Å; P105-E425 HydrophobicContact CG-CB 4.46Å; P105-V450 HydrophobicContact CB-CG2 3.68Å; P105-V450 HydrophobicContact CG-CG2 3.99Å
106S96.2Very high96.5Very high38 Ų3822 Ų2227%0.26613%0.133SC..THydrogen-bonded Turntrans-70.6-19.9174.567.20000114.9L104 K108 E425L104-S106 PolarHBondContact O-N 2.7Å; S106-K108 PolarHBondContact O-N 3.28Å; S106-K108 WeakPolarHBondContact OG-CD 3.45Å; S106-K108 WeakPolarHBondContact OG-CG 3.43Å; S106-K108 PolarHBondContact OG-N 3Å; S106-E425 WeakPolarHBondContact CB-OE1 3.32Å; S106-E425 WeakPolarHBondContact CB-OE2 3.22Å; S106-E425 PolarHBondContact N-OE2 2.82Å; S106-E425 VanDerWaalsContact OG-CD 3.32Å; S106-E425 PolarHBondContact OG-OE1 2.95Å; S106-E425 PolarHBondContact OG-OE2 3.47Å
107G96.7Very high96.8Very high33 Ų3322.4 Ų22.434%0.3413%0.134SC..  trans67.412.4-172.700000115.1N101 L104 P105N101-G107 VanDerWaalsContact CG-O 3.3Å; N101-G107 VanDerWaalsContact ND2-CA 3.32Å; N101-G107 WeakPolarHBondContact ND2-CA 3.37Å; N101-G107 PolarHBondContact ND2-O 3.42Å; L104-G107 PolarHBondContact O-N 2.98Å; P105-G107 VanDerWaalsContact C-N 3.3Å; P105-G107 PolarHBondContact O-N 2.87Å
108K97.7Very high97.1Very high8 Ų821 Ų214%0.03513%0.128CC..  trans-63.1139.1-175.8-69.2175.5180177.30112.5S106 Q112 L113 E116 S427 E456S106-K108 PolarHBondContact O-N 3.28Å; S106-K108 WeakPolarHBondContact OG-CD 3.45Å; S106-K108 WeakPolarHBondContact OG-CG 3.43Å; S106-K108 PolarHBondContact OG-N 3Å; K108-Q112 HydrophobicContact CB-CB 4.37Å; K108-Q112 HydrophobicContact CB-CG 4.33Å; K108-Q112 HydrophobicContact CD-CG 4.37Å; K108-Q112 HydrophobicContact CG-CG 4.1Å; K108-L113 HydrophobicContact CB-CD2 3.89Å; K108-L113 HydrophobicContact CB-CG 4.01Å; K108-L113 HydrophobicContact CD-CD2 3.92Å; K108-E116 WeakPolarHBondContact CE-OE1 3.48Å; K108-E116 WeakPolarHBondContact CE-OE2 3.36Å; K108-E116 IonicContact NZ-OE1 2.73Å; K108-E116 PolarHBondContact NZ-OE1 3.08Å; K108-E116 IonicContact NZ-OE2 3.9Å; K108-E116 PolarHBondContact NZ-OE2 3.4Å; K108-S427 PolarHBondContact NZ-OG 3.37Å; K108-S427 VanDerWaalsContact NZ-OG 3.08Å; K108-E456 WeakPolarHBondContact CE-OE1 3.45Å; K108-E456 IonicContact NZ-OE1 2.76Å; K108-E456 PolarHBondContact NZ-OE1 2.46Å
109S97.6Very high97.2Very high6 Ų623 Ų234%0.04214%0.138CC..BIsolated β-bridgetrans-75.5162.8170.268.60000111.7F111 Q112 L113S109-F111 VanDerWaalsContact C-N 3.27Å; S109-F111 PolarHBondContact O-N 3.33Å; S109-Q112 PolarHBondContact O-N 2.98Å; S109-Q112 VanDerWaalsContact O-N 3.16Å; S109-Q112 WeakPolarHBondContact OG-CB 3.2Å; S109-Q112 PolarHBondContact OG-N 3.4Å; S109-Q112 VanDerWaalsContact OG-N 3.14Å; S109-L113 WeakPolarHBondContact O-CG 3.47Å; S109-L113 PolarHBondContact O-N 2.98Å
110L97.8Very high97.4Very high2 Ų222.6 Ų22.61%0.0114%0.136CC..Hα-helixtrans-58.1-38.8172.9-65.5178.5000112.4G98 Y100 L113 Q114 I231 L381G98-L110 PolarHBondContact O-N 2.92Å; Y100-L110 PolarHBondContact O-N 3.43Å; L110-L113 HydrophobicContact CD2-CD1 4.5Å; L110-Q114 VanDerWaalsContact O-CG 3.24Å; L110-Q114 WeakPolarHBondContact O-CG 3.44Å; L110-Q114 PolarHBondContact O-N 3.06Å; L110-I231 HydrophobicContact CD2-CB 4.24Å; L110-I231 HydrophobicContact CD2-CD1 4.46Å; L110-I231 HydrophobicContact CD2-CG1 4.09Å; L110-L381 HydrophobicContact CD1-CD2 3.93Å
111F98.1Very high97.5Very high0 Ų020 Ų200%013%0.125CC..Hα-helixtrans-62.6-43.9174.8-74-43.5000112.1L82 S84 G98 F99 S109 Q114 A115 V150 F153 F154 F160 V228L82-F111 HydrophobicContact CD2-CD1 3.78Å; L82-F111 HydrophobicContact CD2-CE1 3.5Å; S84-F111 WeakPolarHBondContact OG-CZ 3.47Å; G98-F111 VanDerWaalsContact CA-CE2 3.49Å; G98-F111 WeakPolarHBondContact O-CD2 3.27Å; G98-F111 PolarHBondContact O-N 2.86Å; F99-F111 AromaticContact CD1-CD2 3.77Å; F99-F111 HydrophobicContact CD1-CD2 3.77Å; F99-F111 AromaticContact CD1-CE2 3.54Å; F99-F111 HydrophobicContact CD1-CE2 3.54Å; F99-F111 HydrophobicContact CE1-CD2 4.13Å; F99-F111 AromaticContact CE1-CE2 3.66Å; F99-F111 HydrophobicContact CE1-CE2 3.66Å; S109-F111 VanDerWaalsContact C-N 3.27Å; S109-F111 PolarHBondContact O-N 3.33Å; F111-Q114 PolarHBondContact O-N 3.3Å; F111-A115 WeakPolarHBondContact O-CB 3.25Å; F111-A115 PolarHBondContact O-N 2.65Å; F111-V150 HydrophobicContact CE2-CG1 4.31Å; F111-V150 HydrophobicContact CE2-CG2 4.18Å; F111-V150 HydrophobicContact CZ-CG1 4.1Å; F111-V150 HydrophobicContact CZ-CG2 4.08Å; F111-F153 HydrophobicContact CB-CE1 4.36Å; F111-F153 AromaticContact CD2-CD1 3.88Å; F111-F153 HydrophobicContact CD2-CD1 3.88Å; F111-F153 AromaticContact CD2-CE1 3.92Å; F111-F153 HydrophobicContact CD2-CE1 3.92Å; F111-F154 HydrophobicContact CB-CE1 4.38Å; F111-F154 HydrophobicContact CB-CE2 4.43Å; F111-F154 HydrophobicContact CB-CZ 3.84Å; F111-F154 HydrophobicContact CD1-CE2 4.04Å; F111-F154 AromaticContact CD1-CZ 3.83Å; F111-F154 HydrophobicContact CD1-CZ 3.83Å; F111-F154 HydrophobicContact CD2-CE2 4.06Å; F111-F154 HydrophobicContact CD2-CZ 4.3Å; F111-F154 HydrophobicContact CE1-CE2 4.25Å; F111-F154 HydrophobicContact CE1-CZ 4.44Å; F111-F154 HydrophobicContact CE2-CE2 4.27Å; F111-F154 AromaticContact CG-CE2 3.95Å; F111-F154 HydrophobicContact CG-CE2 3.95Å; F111-F154 AromaticContact CG-CZ 3.76Å; F111-F154 HydrophobicContact CG-CZ 3.76Å; F111-F154 HydrophobicContact CZ-CE2 4.36Å; F111-F160 HydrophobicContact CB-CE2 4.13Å; F111-V228 HydrophobicContact CD1-CG2 4.23Å; F111-V228 HydrophobicContact CE1-CG2 3.9Å
112Q98.3Very high97.7Very high47 Ų4717.2 Ų17.222%0.2211%0.111CC..Hα-helixtrans-63.8-46.5179.2-177.5172.33.100111.7K108 S109 Q114 A115 E116 F160K108-Q112 HydrophobicContact CB-CB 4.37Å; K108-Q112 HydrophobicContact CB-CG 4.33Å; K108-Q112 HydrophobicContact CD-CG 4.37Å; K108-Q112 HydrophobicContact CG-CG 4.1Å; S109-Q112 PolarHBondContact O-N 2.98Å; S109-Q112 VanDerWaalsContact O-N 3.16Å; S109-Q112 WeakPolarHBondContact OG-CB 3.2Å; S109-Q112 PolarHBondContact OG-N 3.4Å; S109-Q112 VanDerWaalsContact OG-N 3.14Å; Q112-Q114 PolarHBondContact O-N 3.39Å; Q112-A115 PolarHBondContact O-N 3.32Å; Q112-E116 HydrophobicContact CG-CG 4.27Å; Q112-E116 VanDerWaalsContact CG-OE1 3.24Å; Q112-E116 WeakPolarHBondContact CG-OE1 3.32Å; Q112-E116 PolarHBondContact NE2-OE1 2.88Å; Q112-E116 WeakPolarHBondContact O-CB 3.29Å; Q112-E116 WeakPolarHBondContact O-CG 3.47Å; Q112-E116 PolarHBondContact O-N 3.31Å; Q112-F160 HydrophobicContact CB-CD1 3.7Å; Q112-F160 HydrophobicContact CB-CE1 3.77Å; Q112-F160 HydrophobicContact CB-CG 4.13Å; Q112-F160 HydrophobicContact CB-CZ 4.27Å; Q112-F160 HydrophobicContact CG-CB 4.5Å; Q112-F160 HydrophobicContact CG-CD1 3.62Å; Q112-F160 HydrophobicContact CG-CE1 4.09Å; Q112-F160 HydrophobicContact CG-CG 4.16Å
113L98.5Very high97.7Very high5 Ų519.4 Ų19.43%0.02613%0.126CC..Hα-helixtrans-55.7-41.5177-68.5171.5000111.7L104 K108 S109 L110 R117 I231 P428L104-L113 HydrophobicContact CD1-CD1 3.93Å; L104-L113 HydrophobicContact CD1-CD2 4.17Å; K108-L113 HydrophobicContact CB-CD2 3.89Å; K108-L113 HydrophobicContact CB-CG 4.01Å; K108-L113 HydrophobicContact CD-CD2 3.92Å; S109-L113 WeakPolarHBondContact O-CG 3.47Å; S109-L113 PolarHBondContact O-N 2.98Å; L110-L113 HydrophobicContact CD2-CD1 4.5Å; L113-R117 VanDerWaalsContact O-CG 3.28Å; L113-R117 WeakPolarHBondContact O-CG 3.25Å; L113-R117 PolarHBondContact O-N 3.45Å; L113-I231 HydrophobicContact CD1-CD1 4.28Å; L113-I231 HydrophobicContact CD1-CG1 4.01Å; L113-P428 HydrophobicContact CD2-CG 3.79Å
114Q98.4Very high97.8Very high2 Ų219.3 Ų19.31%0.00912%0.115CC..Hα-helixtrans-73.5-38179.4-67.7171.325.500112.6L110 F111 Q112 R117 L118 W138 Y226 V228 V233 V235L110-Q114 VanDerWaalsContact O-CG 3.24Å; L110-Q114 WeakPolarHBondContact O-CG 3.44Å; L110-Q114 PolarHBondContact O-N 3.06Å; F111-Q114 PolarHBondContact O-N 3.3Å; Q112-Q114 PolarHBondContact O-N 3.39Å; Q114-R117 PolarHBondContact O-N 3.3Å; Q114-L118 PolarHBondContact O-N 2.83Å; Q114-W138 HydrophobicContact CB-CH2 3.8Å; Q114-W138 HydrophobicContact CB-CZ2 3.85Å; Q114-Y226 HydrophobicContact CG-CE2 4.38Å; Q114-Y226 VanDerWaalsContact OE1-CE2 3.22Å; Q114-Y226 PolarHBondContact OE1-OH 3.11Å; Q114-V228 PolarHBondContact NE2-O 3.32Å; Q114-V233 HydrophobicContact CG-CG1 4.09Å; Q114-V235 HydrophobicContact CB-CG2 3.99Å; Q114-V235 HydrophobicContact CG-CG2 3.89Å
115A98.6Very high97.8Very high0 Ų018.9 Ų18.90%011%0.113CC..Hα-helixtrans-61.7-46.6175.900000111.4F111 Q112 R117 L118 L119 W138 F160 L162F111-A115 WeakPolarHBondContact O-CB 3.25Å; F111-A115 PolarHBondContact O-N 2.65Å; Q112-A115 PolarHBondContact O-N 3.32Å; A115-R117 VanDerWaalsContact C-N 3.33Å; A115-R117 PolarHBondContact O-N 3.49Å; A115-L118 WeakPolarHBondContact O-CB 3.4Å; A115-L118 PolarHBondContact O-N 2.92Å; A115-L118 VanDerWaalsContact O-N 3.13Å; A115-L119 PolarHBondContact O-N 3.21Å; A115-W138 HydrophobicContact CB-CH2 4.01Å; A115-W138 HydrophobicContact CB-CZ3 3.6Å; A115-F160 HydrophobicContact CB-CB 3.73Å; A115-F160 HydrophobicContact CB-CD2 4.22Å; A115-F160 HydrophobicContact CB-CG 4.3Å; A115-L162 HydrophobicContact CB-CD1 3.69Å; A115-L162 HydrophobicContact CB-CG 4.24Å
116E98.4Very high97.8Very high8 Ų817.1 Ų17.14%0.03710%0.102CC..Hα-helixtrans-66.2-34.8-180-71.5179.6-169.800112K108 Q112 L118 L119 R120 P428 L429K108-E116 WeakPolarHBondContact CE-OE1 3.48Å; K108-E116 WeakPolarHBondContact CE-OE2 3.36Å; K108-E116 IonicContact NZ-OE1 2.73Å; K108-E116 PolarHBondContact NZ-OE1 3.08Å; K108-E116 IonicContact NZ-OE2 3.9Å; K108-E116 PolarHBondContact NZ-OE2 3.4Å; Q112-E116 HydrophobicContact CG-CG 4.27Å; Q112-E116 VanDerWaalsContact CG-OE1 3.24Å; Q112-E116 WeakPolarHBondContact CG-OE1 3.32Å; Q112-E116 PolarHBondContact NE2-OE1 2.88Å; Q112-E116 WeakPolarHBondContact O-CB 3.29Å; Q112-E116 WeakPolarHBondContact O-CG 3.47Å; Q112-E116 PolarHBondContact O-N 3.31Å; E116-L118 VanDerWaalsContact C-N 3.33Å; E116-L118 PolarHBondContact O-N 3.01Å; E116-L119 PolarHBondContact O-N 2.69Å; E116-R120 WeakPolarHBondContact O-CB 3.45Å; E116-R120 PolarHBondContact O-N 3.1Å; E116-P428 HydrophobicContact CB-CB 3.79Å; E116-P428 HydrophobicContact CB-CG 4.26Å; E116-P428 WeakPolarHBondContact OE2-CD 3.09Å; E116-L429 HydrophobicContact CB-CD2 3.84Å; E116-L429 HydrophobicContact CB-CG 3.81Å; E116-L429 HydrophobicContact CG-CD1 4.1Å; E116-L429 HydrophobicContact CG-CD2 3.87Å; E116-L429 HydrophobicContact CG-CG 3.68Å
117R98.4Very high97.8Very high13 Ų1320.6 Ų20.65%0.04912%0.117CC..Hα-helixtrans-60.4-40.6171-74.6174.8-177.4151.68.4112.3L113 Q114 A115 R120 L121 I231 V233 P428 Y432L113-R117 VanDerWaalsContact O-CG 3.28Å; L113-R117 WeakPolarHBondContact O-CG 3.25Å; L113-R117 PolarHBondContact O-N 3.45Å; Q114-R117 PolarHBondContact O-N 3.3Å; A115-R117 VanDerWaalsContact C-N 3.33Å; A115-R117 PolarHBondContact O-N 3.49Å; R117-R120 PolarHBondContact O-N 2.78Å; R117-L121 PolarHBondContact O-N 3.18Å; R117-I231 PolarHBondContact NH1-O 3.04Å; R117-I231 PolarHBondContact NH2-O 3.05Å; R117-V233 WeakPolarHBondContact CD-O 3.49Å; R117-V233 PolarHBondContact NH1-O 3.1Å; R117-P428 HydrophobicContact CG-CB 3.73Å; R117-Y432 HydrophobicContact CB-CD2 4.02Å; R117-Y432 HydrophobicContact CB-CE2 4.06Å; R117-Y432 HydrophobicContact CG-CD2 4.28Å; R117-Y432 HydrophobicContact CG-CE2 4.48Å
118L98.6Very high97.7Very high0 Ų024.8 Ų24.80%012%0.123CC..Hα-helixtrans-66.1-45.3176-71.7171.9000111.5V80 Q114 A115 E116 R120 L121 Q122 I136 W138 L162 V235 A236V80-L118 HydrophobicContact CG1-CD2 4.4Å; V80-L118 HydrophobicContact CG2-CD1 4.14Å; V80-L118 HydrophobicContact CG2-CD2 4.13Å; Q114-L118 PolarHBondContact O-N 2.83Å; A115-L118 WeakPolarHBondContact O-CB 3.4Å; A115-L118 PolarHBondContact O-N 2.92Å; A115-L118 VanDerWaalsContact O-N 3.13Å; E116-L118 VanDerWaalsContact C-N 3.33Å; E116-L118 PolarHBondContact O-N 3.01Å; L118-R120 VanDerWaalsContact C-N 3.28Å; L118-R120 PolarHBondContact O-N 2.85Å; L118-L121 PolarHBondContact O-N 3.48Å; L118-Q122 VanDerWaalsContact O-CG 3.28Å; L118-Q122 WeakPolarHBondContact O-CG 3.36Å; L118-Q122 PolarHBondContact O-N 2.89Å; L118-I136 HydrophobicContact CD2-CB 4.09Å; L118-I136 HydrophobicContact CD2-CD1 4Å; L118-I136 HydrophobicContact CD2-CG2 3.75Å; L118-W138 HydrophobicContact CD1-CB 4.09Å; L118-W138 HydrophobicContact CD1-CD2 3.52Å; L118-W138 HydrophobicContact CD1-CE3 3.44Å; L118-W138 VanDerWaalsContact CD1-CE3 3.44Å; L118-W138 HydrophobicContact CD1-CG 3.89Å; L118-W138 HydrophobicContact CD1-CH2 4.5Å; L118-W138 HydrophobicContact CD1-CZ3 3.99Å; L118-L162 HydrophobicContact CB-CD2 4.34Å; L118-V235 HydrophobicContact CD1-CG1 4.36Å; L118-V235 HydrophobicContact CD2-CG1 3.66Å; L118-V235 HydrophobicContact CG-CG1 3.92Å; L118-A236 HydrophobicContact CD2-CB 4.09Å
119L98.1Very high97.5Very high41 Ų4126.5 Ų26.522%0.21514%0.136CC..Hα-helixtrans-56.4-44.9175-73.3172.7000111.3A115 E116 Q122 S123 F160 L162 L429A115-L119 PolarHBondContact O-N 3.21Å; E116-L119 PolarHBondContact O-N 2.69Å; L119-Q122 PolarHBondContact O-N 2.81Å; L119-S123 PolarHBondContact O-N 2.91Å; L119-F160 VanDerWaalsContact CD1-O 3.29Å; L119-F160 WeakPolarHBondContact CD1-O 3.41Å; L119-L162 HydrophobicContact CD1-CD2 4.49Å; L119-L162 HydrophobicContact CD2-CD2 3.71Å; L119-L162 HydrophobicContact CD2-CG 4.47Å; L119-L162 HydrophobicContact CG-CD2 3.69Å; L119-L162 HydrophobicContact CG-CG 4.38Å; L119-L429 HydrophobicContact CB-CD2 3.86Å; L119-L429 HydrophobicContact CD1-CD2 3.86Å
120R97.8Very high97.3Very high29 Ų2929.7 Ų29.711%0.10917%0.17CC..Hα-helixtrans-62.7-46.4178.8-179.351.8178.1173.3-20.5112.4E116 R117 L118 Q122 S123 M124 P428 L430 E435 N436E116-R120 WeakPolarHBondContact O-CB 3.45Å; E116-R120 PolarHBondContact O-N 3.1Å; R117-R120 PolarHBondContact O-N 2.78Å; L118-R120 VanDerWaalsContact C-N 3.28Å; L118-R120 PolarHBondContact O-N 2.85Å; R120-Q122 VanDerWaalsContact C-N 3.32Å; R120-Q122 PolarHBondContact O-N 3.12Å; R120-S123 WeakPolarHBondContact O-CB 3.38Å; R120-S123 PolarHBondContact O-N 3.19Å; R120-M124 HydrophobicContact CG-CG 4.4Å; R120-M124 HydrophobicContact CG-SD 3.84Å; R120-M124 VanDerWaalsContact O-CG 3.29Å; R120-M124 WeakPolarHBondContact O-CG 3.48Å; R120-M124 PolarHBondContact O-N 3.11Å; R120-P428 WeakPolarHBondContact CB-O 3.47Å; R120-P428 WeakPolarHBondContact CG-O 3.04Å; R120-L430 PolarHBondContact NE-O 2.88Å; R120-L430 PolarHBondContact NH2-O 3.24Å; R120-E435 IonicContact CZ-OE1 3.6Å; R120-E435 IonicContact NE-OE1 3.76Å; R120-E435 PolarHBondContact NE-OE1 2.95Å; R120-E435 IonicContact NH2-OE1 3.55Å; R120-N436 PolarHBondContact NH2-ND2 3.04Å
121L97.6Very high97.2Very high0 Ų036.3 Ų36.30%020%0.201CC..Hα-helixtrans-59.4-40.7175.7-80.2178000113M70 I73 R117 L118 S123 M124 A125 I136 V235 A236 P238 Y432M70-L121 HydrophobicContact SD-CD2 4.33Å; I73-L121 HydrophobicContact CD1-CD1 4.4Å; I73-L121 HydrophobicContact CD1-CD2 4.46Å; R117-L121 PolarHBondContact O-N 3.18Å; L118-L121 PolarHBondContact O-N 3.48Å; L121-S123 VanDerWaalsContact C-N 3.35Å; L121-M124 HydrophobicContact CD2-SD 4.45Å; L121-M124 PolarHBondContact O-N 3.43Å; L121-A125 VanDerWaalsContact O-CB 3.29Å; L121-A125 WeakPolarHBondContact O-CB 3.34Å; L121-A125 PolarHBondContact O-N 3.25Å; L121-I136 HydrophobicContact CB-CD1 3.96Å; L121-I136 HydrophobicContact CD1-CD1 4.32Å; L121-V235 WeakPolarHBondContact CD1-O 3.17Å; L121-A236 HydrophobicContact CD1-CB 3.69Å; L121-P238 HydrophobicContact CD2-CG 3.73Å; L121-Y432 HydrophobicContact CD1-CD2 4.03Å; L121-Y432 HydrophobicContact CD1-CE2 3.4Å; L121-Y432 HydrophobicContact CD2-CD1 3.95Å; L121-Y432 HydrophobicContact CD2-CD2 3.92Å; L121-Y432 HydrophobicContact CD2-CE1 3.98Å; L121-Y432 HydrophobicContact CD2-CE2 3.93Å; L121-Y432 HydrophobicContact CD2-CG 3.92Å; L121-Y432 HydrophobicContact CG-CD1 4.5Å; L121-Y432 HydrophobicContact CG-CD2 3.57Å; L121-Y432 HydrophobicContact CG-CE1 4.47Å; L121-Y432 HydrophobicContact CG-CE2 3.5Å; L121-Y432 VanDerWaalsContact CG-CE2 3.5Å; L121-Y432 HydrophobicContact CG-CG 4.08Å
122Q97.9Very high97Very high14 Ų1445.2 Ų45.27%0.06524%0.24CC..Hα-helixtrans-63.7-40.7176.6-68.6169.9164.100111.8L118 L119 R120 S126 V133 I136L118-Q122 VanDerWaalsContact O-CG 3.28Å; L118-Q122 WeakPolarHBondContact O-CG 3.36Å; L118-Q122 PolarHBondContact O-N 2.89Å; L119-Q122 PolarHBondContact O-N 2.81Å; R120-Q122 VanDerWaalsContact C-N 3.32Å; R120-Q122 PolarHBondContact O-N 3.12Å; Q122-S126 WeakPolarHBondContact O-CB 3.31Å; Q122-S126 PolarHBondContact O-N 2.55Å; Q122-S126 PolarHBondContact O-OG 3.06Å; Q122-V133 HydrophobicContact CB-CG2 4.48Å; Q122-V133 WeakPolarHBondContact O-CG2 3.24Å; Q122-I136 HydrophobicContact CG-CD1 4.13Å; Q122-I136 HydrophobicContact CG-CG1 3.99Å
123S96.9Very high96.9Very high49 Ų4943.6 Ų43.634%0.34323%0.233SC..Hα-helixtrans-61.1-53.5173.4-173.90000110.4L119 R120 L121 A125 S126 D127L119-S123 PolarHBondContact O-N 2.91Å; R120-S123 WeakPolarHBondContact O-CB 3.38Å; R120-S123 PolarHBondContact O-N 3.19Å; L121-S123 VanDerWaalsContact C-N 3.35Å; S123-A125 VanDerWaalsContact C-N 3.27Å; S123-A125 PolarHBondContact O-N 2.87Å; S123-S126 WeakPolarHBondContact O-CA 3.5Å; S123-S126 WeakPolarHBondContact O-CB 3.32Å; S123-S126 PolarHBondContact O-N 3.04Å; S123-D127 VanDerWaalsContact O-CG 3.22Å; S123-D127 PolarHBondContact O-N 3.06Å
124M97.1Very high96.8Very high40 Ų4046.1 Ų46.120%0.19725%0.254CS..Hα-helixtrans-58.2-39.2-179.4-67.7166.76600112.4M70 R120 L121 R128 E435M70-M124 HydrophobicContact CE-CB 3.87Å; R120-M124 HydrophobicContact CG-CG 4.4Å; R120-M124 HydrophobicContact CG-SD 3.84Å; R120-M124 VanDerWaalsContact O-CG 3.29Å; R120-M124 WeakPolarHBondContact O-CG 3.48Å; R120-M124 PolarHBondContact O-N 3.11Å; L121-M124 HydrophobicContact CD2-SD 4.45Å; L121-M124 PolarHBondContact O-N 3.43Å; M124-R128 VanDerWaalsContact O-CB 3.27Å; M124-R128 WeakPolarHBondContact O-CB 3.49Å; M124-R128 PolarHBondContact O-N 3.07Å; M124-E435 HydrophobicContact CE-CG 3.85Å; M124-E435 HydrophobicContact SD-CG 4.27Å
125A97.4Very high96.7Very high0 Ų048.9 Ų48.90%027%0.269CS..Hα-helixtrans-70-34.2176.700000112.2M70 I73 A74 L121 S123 S129 V133M70-A125 HydrophobicContact CE-CB 3.76Å; I73-A125 HydrophobicContact CB-CB 4.47Å; I73-A125 HydrophobicContact CG2-CB 3.74Å; A74-A125 HydrophobicContact CB-CB 4.38Å; L121-A125 VanDerWaalsContact O-CB 3.29Å; L121-A125 WeakPolarHBondContact O-CB 3.34Å; L121-A125 PolarHBondContact O-N 3.25Å; S123-A125 VanDerWaalsContact C-N 3.27Å; S123-A125 PolarHBondContact O-N 2.87Å; A125-S129 WeakPolarHBondContact O-CB 3.42Å; A125-S129 PolarHBondContact O-N 2.68Å; A125-S129 VanDerWaalsContact O-N 3.08Å; A125-S129 PolarHBondContact O-OG 3.11Å; A125-V133 HydrophobicContact CB-CG1 4.05Å; A125-V133 HydrophobicContact CB-CG2 4.01Å
126S97.6Very high96.7Very high24 Ų2449 Ų4917%0.16827%0.27CS..Hα-helixtrans-66.5-48.1173.2-57.30000111.5Q122 S123 R128 S129 G130 Q131 V133Q122-S126 WeakPolarHBondContact O-CB 3.31Å; Q122-S126 PolarHBondContact O-N 2.55Å; Q122-S126 PolarHBondContact O-OG 3.06Å; S123-S126 WeakPolarHBondContact O-CA 3.5Å; S123-S126 WeakPolarHBondContact O-CB 3.32Å; S123-S126 PolarHBondContact O-N 3.04Å; S126-R128 VanDerWaalsContact C-N 3.32Å; S126-R128 PolarHBondContact O-N 3.3Å; S126-S129 PolarHBondContact O-N 3.11Å; S126-S129 PolarHBondContact O-OG 3.12Å; S126-G130 PolarHBondContact O-N 3.22Å; S126-Q131 WeakPolarHBondContact CA-O 3.35Å; S126-Q131 WeakPolarHBondContact CB-O 3.47Å; S126-Q131 PolarHBondContact O-N 2.77Å; S126-V133 PolarHBondContact OG-N 3.18Å
127D95.9Very high96.7Very high111 Ų11148.9 Ų48.959%0.59427%0.27SS*.Hα-helixtrans-59.3-45178.6-60.5-26.5000110.8S123 S129 G130S123-D127 VanDerWaalsContact O-CG 3.22Å; S123-D127 PolarHBondContact O-N 3.06Å; D127-S129 PolarHBondContact O-N 3.42Å; D127-G130 PolarHBondContact O-N 3.07Å
128R94.3Very high96.8Very high121 Ų12148.3 Ų48.346%0.45727%0.267SS..Hα-helixtrans-66.5-35.4179.3-174.5173.7-174.2-114-1.5113.6S67 M70 D71 M124 S126S67-R128 PolarHBondContact O-NH1 3.32Å; S67-R128 PolarHBondContact OG-NH2 3.23Å; M70-R128 VanDerWaalsContact CB-NH1 3.27Å; D71-R128 IonicContact OD1-CZ 3.44Å; D71-R128 IonicContact OD1-NH1 2.86Å; D71-R128 PolarHBondContact OD1-NH1 2.94Å; D71-R128 IonicContact OD1-NH2 3.25Å; M124-R128 VanDerWaalsContact O-CB 3.27Å; M124-R128 WeakPolarHBondContact O-CB 3.49Å; M124-R128 PolarHBondContact O-N 3.07Å; S126-R128 VanDerWaalsContact C-N 3.32Å; S126-R128 PolarHBondContact O-N 3.3Å
129S93.9Very high96.8Very high44 Ų4448.3 Ų48.331%0.30827%0.267SS..Hα-helixtrans-91.2-9.2-177.665.70000113.8A125 S126 D127 Q131 V133A125-S129 WeakPolarHBondContact O-CB 3.42Å; A125-S129 PolarHBondContact O-N 2.68Å; A125-S129 VanDerWaalsContact O-N 3.08Å; A125-S129 PolarHBondContact O-OG 3.11Å; S126-S129 PolarHBondContact O-N 3.11Å; S126-S129 PolarHBondContact O-OG 3.12Å; D127-S129 PolarHBondContact O-N 3.42Å; S129-Q131 PolarHBondContact O-N 3.05Å; S129-Q131 PolarHBondContact OG-O 2.82Å; S129-V133 WeakPolarHBondContact OG-CG1 3.49Å
130G94.2Very high96.8Very high74 Ų7446.3 Ų46.376%0.76326%0.257SS*.THydrogen-bonded Turntrans69.610.9-176.600000114.3S126 D127S126-G130 PolarHBondContact O-N 3.22Å; D127-G130 PolarHBondContact O-N 3.07Å
131Q94.7Very high96.8Very high140 Ų14045 Ų4565%0.65425%0.252SS*.SBendtrans-146.4155.3-178.963.8-174.2-36.700110.7S126 S129 V133S126-Q131 WeakPolarHBondContact CA-O 3.35Å; S126-Q131 WeakPolarHBondContact CB-O 3.47Å; S126-Q131 PolarHBondContact O-N 2.77Å; S129-Q131 PolarHBondContact O-N 3.05Å; S129-Q131 PolarHBondContact OG-O 2.82Å; Q131-V133 PolarHBondContact O-N 3.49Å
132K94.5Very high96.8Very high188 Ų18845 Ų4582%0.81725%0.252SS*.PPolyproline II helixtrans-63.4120.2175.7-174.9174.4-176.7174.60110.2
133V96.4Very high96.5Very high12 Ų1244.4 Ų44.47%0.07325%0.249CC..PPolyproline II helixtrans-83.1162.3177.7-55.70000111.7A74 Q122 A125 S126 S129 Q131A74-V133 HydrophobicContact CB-CG1 3.97Å; Q122-V133 HydrophobicContact CB-CG2 4.48Å; Q122-V133 WeakPolarHBondContact O-CG2 3.24Å; A125-V133 HydrophobicContact CB-CG1 4.05Å; A125-V133 HydrophobicContact CB-CG2 4.01Å; S126-V133 PolarHBondContact OG-N 3.18Å; S129-V133 WeakPolarHBondContact OG-CG1 3.49Å; Q131-V133 PolarHBondContact O-N 3.49Å
134A95.2Very high96.2Very high58 Ų5848.5 Ų48.548%0.47926%0.263SS..PPolyproline II helixtrans-64.8146.7169.600000110.9
135N97.8Very high95.7Very high60 Ų6051.5 Ų51.532%0.32128%0.28SS..PPolyproline II helixtrans-64.5140.1175-64.3-27.5000110.8T137 S163 Q166N135-T137 PolarHBondContact O-N 2.69Å; N135-S163 WeakPolarHBondContact ND2-CB 3.38Å; N135-Q166 HydrophobicContact CB-CB 3.72Å; N135-Q166 HydrophobicContact CB-CG 4.4Å
136I98.6Very high95.4Very high4 Ų451.5 Ų51.52%0.02128%0.28CS..PPolyproline II helixtrans-67.1120.9172.1-60.9172000107.2I73 V80 L118 L121 Q122 W138 Q166 A236I73-I136 HydrophobicContact CG2-CD1 3.94Å; I73-I136 HydrophobicContact CG2-CG1 4.11Å; V80-I136 HydrophobicContact CG1-CG2 4.32Å; V80-I136 HydrophobicContact CG2-CG2 4.48Å; L118-I136 HydrophobicContact CD2-CB 4.09Å; L118-I136 HydrophobicContact CD2-CD1 4Å; L118-I136 HydrophobicContact CD2-CG2 3.75Å; L121-I136 HydrophobicContact CB-CD1 3.96Å; L121-I136 HydrophobicContact CD1-CD1 4.32Å; Q122-I136 HydrophobicContact CG-CD1 4.13Å; Q122-I136 HydrophobicContact CG-CG1 3.99Å; I136-W138 PolarHBondContact O-N 3.08Å; I136-Q166 PolarHBondContact O-OE1 3.32Å; I136-A236 HydrophobicContact CD1-CB 4.15Å; I136-A236 HydrophobicContact CG2-CB 4.44Å
137T98.6Very high95.3Very high5 Ų553.2 Ų53.23%0.03129%0.285CS..EExtended strand (participates in β ladder)trans-71.2126.3179.7-60.90000109.5A79 V80 N135 Q166 I168 L215 K218A79-T137 CarbonylContact C-O 3.56Å; A79-T137 VanDerWaalsContact CA-O 3.29Å; A79-T137 WeakPolarHBondContact CA-O 3.37Å; A79-T137 WeakPolarHBondContact CB-O 3.42Å; V80-T137 PolarHBondContact N-O 2.55Å; N135-T137 PolarHBondContact O-N 2.69Å; T137-Q166 WeakPolarHBondContact CA-O 3.38Å; T137-I168 HydrophobicContact CG2-CD1 3.62Å; T137-I168 HydrophobicContact CG2-CG1 4.26Å; T137-L215 HydrophobicContact CG2-CD2 3.98Å; T137-K218 HydrophobicContact CG2-CD 4.27Å; T137-K218 WeakPolarHBondContact OG1-CD 3.36Å
138W98.8Very high95.2Very high0 Ų055.4 Ų55.40%029%0.291CS..EExtended strand (participates in β ladder)trans-111.5104.9179.1-167.21.9000110.6V80 L82 Q114 A115 L118 I136 I140 F154 L162 Q166 M167 I168 Y226V80-W138 HydrophobicContact CG2-CB 4.03Å; V80-W138 VanDerWaalsContact CG2-CD1 3.48Å; V80-W138 HydrophobicContact CG2-CG 3.8Å; L82-W138 HydrophobicContact CD2-CZ2 3.73Å; Q114-W138 HydrophobicContact CB-CH2 3.8Å; Q114-W138 HydrophobicContact CB-CZ2 3.85Å; A115-W138 HydrophobicContact CB-CH2 4.01Å; A115-W138 HydrophobicContact CB-CZ3 3.6Å; L118-W138 HydrophobicContact CD1-CB 4.09Å; L118-W138 HydrophobicContact CD1-CD2 3.52Å; L118-W138 HydrophobicContact CD1-CE3 3.44Å; L118-W138 VanDerWaalsContact CD1-CE3 3.44Å; L118-W138 HydrophobicContact CD1-CG 3.89Å; L118-W138 HydrophobicContact CD1-CH2 4.5Å; L118-W138 HydrophobicContact CD1-CZ3 3.99Å; I136-W138 PolarHBondContact O-N 3.08Å; W138-I140 HydrophobicContact CD2-CD1 4.25Å; W138-I140 HydrophobicContact CD2-CG1 4.39Å; W138-I140 HydrophobicContact CG-CG1 4.26Å; W138-F154 HydrophobicContact CH2-CE1 4.39Å; W138-F154 HydrophobicContact CH2-CZ 4.22Å; W138-F154 HydrophobicContact CZ3-CE1 4.06Å; W138-F154 HydrophobicContact CZ3-CZ 4.25Å; W138-L162 HydrophobicContact CE3-CD1 3.41Å; W138-L162 VanDerWaalsContact CE3-CD1 3.41Å; W138-L162 HydrophobicContact CZ3-CD1 3.43Å; W138-L162 VanDerWaalsContact CZ3-CD1 3.43Å; W138-Q166 PolarHBondContact N-O 3.34Å; W138-M167 HydrophobicContact CE3-CE 4.03Å; W138-M167 HydrophobicContact CZ3-CE 4.44Å; W138-M167 WeakPolarHBondContact O-CA 3.48Å; W138-I168 PolarHBondContact O-N 2.84Å; W138-Y226 WeakPolarHBondContact CZ2-OH 3.23Å; W138-Y226 PolarHBondContact NE1-OH 2.71Å
139C98.8Very high95.3Very high0 Ų051 Ų510%028%0.279CS..EExtended strand (participates in β ladder)trans-91127174-53.80000109.4V80 I81 L82 I168 F170 V211V80-C139 PolarHBondContact O-N 2.83Å; I81-C139 CarbonylContact C-O 3.52Å; I81-C139 VanDerWaalsContact CA-O 3.26Å; I81-C139 WeakPolarHBondContact CA-O 3.35Å; I81-C139 HydrophobicContact CG1-CB 3.93Å; L82-C139 PolarHBondContact N-O 2.8Å; C139-I168 CarbonylContact C-O 3.43Å; C139-I168 WeakPolarHBondContact CA-O 3.14Å; C139-I168 HydrophobicContact CB-CB 4.46Å; C139-F170 HydrophobicContact CB-CD1 4.22Å; C139-F170 HydrophobicContact CB-CE1 3.73Å; C139-V211 HydrophobicContact CB-CG1 4.43Å
140I98.6Very high95.4Very high0 Ų048.9 Ų48.90%026%0.264CS..EExtended strand (participates in β ladder)trans-114.3113.6179.7-57-174.8000108.3L82 W138 T142 V150 F154 M167 I168 F169 F170L82-I140 HydrophobicContact CB-CG1 4.33Å; L82-I140 HydrophobicContact CD2-CD1 4.47Å; L82-I140 HydrophobicContact CD2-CG1 4.44Å; L82-I140 HydrophobicContact CD2-CG2 4.44Å; W138-I140 HydrophobicContact CD2-CD1 4.25Å; W138-I140 HydrophobicContact CD2-CG1 4.39Å; W138-I140 HydrophobicContact CG-CG1 4.26Å; I140-T142 HydrophobicContact CG2-CG2 4.14Å; I140-V150 HydrophobicContact CG2-CG1 4.29Å; I140-F154 HydrophobicContact CD1-CD2 4.34Å; I140-F154 HydrophobicContact CD1-CE1 4.48Å; I140-F154 HydrophobicContact CD1-CE2 3.46Å; I140-F154 VanDerWaalsContact CD1-CE2 3.46Å; I140-F154 HydrophobicContact CD1-CZ 3.54Å; I140-M167 HydrophobicContact CD1-CE 3.36Å; I140-M167 HydrophobicContact CG1-CE 4.36Å; I140-I168 PolarHBondContact N-O 2.9Å; I140-F169 HydrophobicContact CB-CD1 3.98Å; I140-F169 HydrophobicContact CB-CE1 4.22Å; I140-F169 HydrophobicContact CD1-CD1 4.47Å; I140-F169 HydrophobicContact CD1-CE1 3.84Å; I140-F169 HydrophobicContact CD1-CZ 4.44Å; I140-F169 HydrophobicContact CG1-CE1 4.44Å; I140-F169 HydrophobicContact CG2-CD1 4.38Å; I140-F170 WeakPolarHBondContact O-CD1 3.34Å; I140-F170 PolarHBondContact O-N 3.06Å; I140-F170 VanDerWaalsContact O-N 3.08Å
141M98.2Very high95.6Very high1 Ų149.1 Ų49.11%0.00524%0.244CC..EExtended strand (participates in β ladder)trans-82.6115174.4-166.5173.876.600109.5L82 L83 S84 G85 F170 Q172 L202L82-M141 PolarHBondContact O-N 3.31Å; L83-M141 HydrophobicContact CB-CE 4.46Å; L83-M141 HydrophobicContact CD2-CE 3.58Å; L83-M141 HydrophobicContact CD2-SD 4.28Å; S84-M141 CarbonylContact C-O 3.34Å; S84-M141 VanDerWaalsContact CA-O 3.29Å; S84-M141 WeakPolarHBondContact CA-O 3.43Å; S84-M141 PolarHBondContact N-O 2.89Å; G85-M141 PolarHBondContact N-O 3.44Å; M141-F170 CarbonylContact C-O 3.56Å; M141-F170 WeakPolarHBondContact CA-O 3.15Å; M141-F170 HydrophobicContact CB-CE1 3.85Å; M141-F170 HydrophobicContact CB-CE2 3.81Å; M141-F170 HydrophobicContact CB-CZ 3.44Å; M141-F170 VanDerWaalsContact CB-CZ 3.44Å; M141-F170 HydrophobicContact CG-CD2 4.18Å; M141-F170 HydrophobicContact CG-CE2 3.59Å; M141-F170 HydrophobicContact CG-CZ 3.79Å; M141-F170 HydrophobicContact SD-CE2 3.95Å; M141-F170 HydrophobicContact SD-CZ 4.25Å; M141-Q172 HydrophobicContact CE-CB 4.48Å; M141-Q172 HydrophobicContact CG-CB 4.15Å; M141-Q172 HydrophobicContact SD-CB 4.07Å; M141-L202 HydrophobicContact CE-CB 4.41Å; M141-L202 VanDerWaalsContact SD-CA 3.54Å; M141-L202 HydrophobicContact SD-CB 3.87Å; M141-L202 HydrophobicContact SD-CD1 3.72Å; M141-L202 HydrophobicContact SD-CG 4.44Å
142T96.6Very high95.7Very high0 Ų044.2 Ų44.20%023%0.228CC..EExtended strand (participates in β ladder)trans-107.6174.7175.5510000111.2I140 E147 V150 F170 T171 Q172I140-T142 HydrophobicContact CG2-CG2 4.14Å; T142-E147 WeakPolarHBondContact OG1-CB 3.35Å; T142-V150 HydrophobicContact CG2-CB 4Å; T142-V150 HydrophobicContact CG2-CG1 4.02Å; T142-V150 HydrophobicContact CG2-CG2 4.12Å; T142-F170 PolarHBondContact N-O 2.83Å; T142-F170 PolarHBondContact OG1-O 3.41Å; T142-T171 WeakPolarHBondContact O-CA 3.48Å; T142-T171 PolarHBondContact OG1-OG1 3.23Å; T142-T171 VanDerWaalsContact OG1-OG1 3.1Å; T142-Q172 WeakPolarHBondContact O-CG 3.04Å; T142-Q172 PolarHBondContact O-N 3.42Å
143S93.3Very high95.9Very high1 Ų136.9 Ų36.91%0.00720%0.196CC..  trans-112.2169163.966.70000109.3G85 L145 T146 E147G85-S143 WeakPolarHBondContact O-CB 3.32Å; G85-S143 PolarHBondContact O-OG 2.88Å; S143-L145 PolarHBondContact O-N 3.18Å; S143-L145 PolarHBondContact OG-N 3.16Å; S143-T146 PolarHBondContact N-OG1 2.93Å; S143-T146 PolarHBondContact O-N 3.17Å; S143-T146 PolarHBondContact OG-OG1 3.32Å; S143-E147 WeakPolarHBondContact O-CB 3.45Å; S143-E147 PolarHBondContact O-N 3.43Å
144Q90.3Very high95.9Very high135 Ų13536.3 Ų36.363%0.63119%0.192SC*.THydrogen-bonded Turntrans-54.9-26.4173.5-65.2-172.412.400112.7T171 L174Q144-T171 HydrophobicContact CG-CG2 4.1Å; Q144-L174 HydrophobicContact CB-CD1 4.29Å; Q144-L174 HydrophobicContact CG-CD1 4Å; Q144-L174 HydrophobicContact CG-CG 4.4Å
145L86.2Confident96.1Very high104 Ų10440.5 Ų40.555%0.54520%0.2SC..THydrogen-bonded Turntrans-78-23.7177.9-59.1175.2000113.5S143S143-L145 PolarHBondContact O-N 3.18Å; S143-L145 PolarHBondContact OG-N 3.16Å
146T91.3Very high96.1Very high0 Ų042.9 Ų42.90%022%0.217CC..THydrogen-bonded Turntrans-116.6-16.8-17362.90000114S84 Q87 P96 S143 H148 S149 V150S84-T146 PolarHBondContact O-OG1 3.46Å; Q87-T146 HydrophobicContact CG-CG2 3.97Å; P96-T146 HydrophobicContact CB-CG2 4.28Å; P96-T146 HydrophobicContact CG-CG2 4.06Å; S143-T146 PolarHBondContact N-OG1 2.93Å; S143-T146 PolarHBondContact O-N 3.17Å; S143-T146 PolarHBondContact OG-OG1 3.32Å; T146-H148 PolarHBondContact O-N 3.14Å; T146-S149 PolarHBondContact O-N 3.11Å; T146-S149 PolarHBondContact O-OG 2.77Å; T146-S149 VanDerWaalsContact O-OG 3.08Å; T146-V150 VanDerWaalsContact O-CB 3.32Å; T146-V150 WeakPolarHBondContact O-CB 3.36Å; T146-V150 WeakPolarHBondContact O-CG2 3.36Å; T146-V150 PolarHBondContact O-N 2.82Å
147E94.5Very high96Very high59 Ų5946.6 Ų46.628%0.27623%0.234SC..Hα-helixtrans-57-52.8-172.3-177.7-177.5165.900113T142 S143 V150 K151 T171T142-E147 WeakPolarHBondContact OG1-CB 3.35Å; S143-E147 WeakPolarHBondContact O-CB 3.45Å; S143-E147 PolarHBondContact O-N 3.43Å; E147-V150 PolarHBondContact O-N 2.82Å; E147-K151 HydrophobicContact CG-CD 4.06Å; E147-K151 WeakPolarHBondContact O-CB 3.48Å; E147-K151 WeakPolarHBondContact O-CG 3.21Å; E147-K151 PolarHBondContact O-N 3.37Å; E147-K151 WeakPolarHBondContact OE1-CE 3.26Å; E147-K151 IonicContact OE1-NZ 2.69Å; E147-K151 PolarHBondContact OE1-NZ 2.87Å; E147-T171 PolarHBondContact OE2-OG1 3.28Å
148H95.4Very high96Very high157 Ų15752.7 Ų52.773%0.72727%0.266SS*.Hα-helixtrans-63-48.4-176.3179.1-87.9000111.6T146 K151 A152T146-H148 PolarHBondContact O-N 3.14Å; H148-K151 PolarHBondContact O-N 2.98Å; H148-A152 WeakPolarHBondContact O-CB 3.47Å; H148-A152 PolarHBondContact O-N 3.5Å
149S95.5Very high95.9Very high29 Ų2955.4 Ų55.420%0.20328%0.277CS..Hα-helixtrans-63.5-45.7179.749.80000110.9P96 F99 T146 K151 A152 F153P96-S149 WeakPolarHBondContact CG-OG 3.49Å; F99-S149 WeakPolarHBondContact CZ-O 3.28Å; T146-S149 PolarHBondContact O-N 3.11Å; T146-S149 PolarHBondContact O-OG 2.77Å; T146-S149 VanDerWaalsContact O-OG 3.08Å; S149-K151 PolarHBondContact O-N 3.2Å; S149-A152 PolarHBondContact O-N 3.34Å; S149-F153 WeakPolarHBondContact O-CB 3.5Å; S149-F153 PolarHBondContact O-N 3.39Å
150V96.9Very high95.9Very high0 Ų056.4 Ų56.40%028%0.281CS..Hα-helixtrans-59.1-48.6178.4171.30000111.4P96 F99 F111 I140 T142 T146 E147 A152 F153 F154 F169P96-V150 HydrophobicContact CB-CG2 3.65Å; P96-V150 HydrophobicContact CG-CG2 3.63Å; F99-V150 HydrophobicContact CE1-CG2 4.26Å; F111-V150 HydrophobicContact CE2-CG1 4.31Å; F111-V150 HydrophobicContact CE2-CG2 4.18Å; F111-V150 HydrophobicContact CZ-CG1 4.1Å; F111-V150 HydrophobicContact CZ-CG2 4.08Å; I140-V150 HydrophobicContact CG2-CG1 4.29Å; T142-V150 HydrophobicContact CG2-CB 4Å; T142-V150 HydrophobicContact CG2-CG1 4.02Å; T142-V150 HydrophobicContact CG2-CG2 4.12Å; T146-V150 VanDerWaalsContact O-CB 3.32Å; T146-V150 WeakPolarHBondContact O-CB 3.36Å; T146-V150 WeakPolarHBondContact O-CG2 3.36Å; T146-V150 PolarHBondContact O-N 2.82Å; E147-V150 PolarHBondContact O-N 2.82Å; V150-A152 PolarHBondContact O-N 2.87Å; V150-F153 PolarHBondContact O-N 3.45Å; V150-F154 HydrophobicContact CG1-CD2 3.97Å; V150-F154 HydrophobicContact CG1-CE2 3.94Å; V150-F154 WeakPolarHBondContact O-CD2 3.42Å; V150-F154 PolarHBondContact O-N 3.36Å; V150-F154 VanDerWaalsContact O-N 3.11Å; V150-F169 HydrophobicContact CG1-CD1 4.2Å; V150-F169 HydrophobicContact CG1-CE1 3.82Å
151K97.3Very high95.8Very high78 Ų7859.2 Ų59.234%0.33931%0.31SS..Hα-helixtrans-60.1-45.3177.3-75.6176.8174.5176.20112E147 H148 S149 F153 K155 F169E147-K151 HydrophobicContact CG-CD 4.06Å; E147-K151 WeakPolarHBondContact O-CB 3.48Å; E147-K151 WeakPolarHBondContact O-CG 3.21Å; E147-K151 PolarHBondContact O-N 3.37Å; E147-K151 WeakPolarHBondContact OE1-CE 3.26Å; E147-K151 IonicContact OE1-NZ 2.69Å; E147-K151 PolarHBondContact OE1-NZ 2.87Å; H148-K151 PolarHBondContact O-N 2.98Å; S149-K151 PolarHBondContact O-N 3.2Å; K151-F153 VanDerWaalsContact C-N 3.33Å; K151-F153 PolarHBondContact O-N 3.27Å; K151-K155 PolarHBondContact O-N 3.06Å; K151-K155 VanDerWaalsContact O-N 3.1Å; K151-F169 HydrophobicContact CD-CB 4.42Å; K151-F169 HydrophobicContact CD-CG 4.45Å; K151-F169 HydrophobicContact CG-CB 4.25Å; K151-F169 HydrophobicContact CG-CD1 3.95Å; K151-F169 HydrophobicContact CG-CD2 4.05Å; K151-F169 HydrophobicContact CG-CE1 4.32Å; K151-F169 HydrophobicContact CG-CE2 4.41Å; K151-F169 HydrophobicContact CG-CG 3.81Å
152A97.5Very high95.8Very high37 Ų3759.4 Ų59.431%0.30631%0.311SS..Hα-helixtrans-61.6-42.7177.600000111.4H148 S149 V150 K155 T156H148-A152 WeakPolarHBondContact O-CB 3.47Å; H148-A152 PolarHBondContact O-N 3.5Å; S149-A152 PolarHBondContact O-N 3.34Å; V150-A152 PolarHBondContact O-N 2.87Å; A152-K155 PolarHBondContact O-N 3.18Å; A152-T156 WeakPolarHBondContact O-CB 3.23Å; A152-T156 PolarHBondContact O-N 3.38Å; A152-T156 PolarHBondContact O-OG1 2.96Å
153F97.4Very high95.8Very high35 Ų3561.5 Ų61.515%0.15433%0.326CS..Hα-helixtrans-61.7-47.3-180-173.8-102.5000112.4F99 F111 S149 V150 K151 K155 T156 H157 F160F99-F153 HydrophobicContact CB-CE2 4.43Å; F99-F153 HydrophobicContact CB-CZ 4.44Å; F99-F153 HydrophobicContact CD1-CB 4.13Å; F99-F153 AromaticContact CD1-CD1 3.62Å; F99-F153 HydrophobicContact CD1-CD1 3.62Å; F99-F153 AromaticContact CD1-CD2 3.87Å; F99-F153 HydrophobicContact CD1-CD2 3.87Å; F99-F153 AromaticContact CD1-CE1 3.87Å; F99-F153 HydrophobicContact CD1-CE1 3.87Å; F99-F153 HydrophobicContact CD1-CE2 4.14Å; F99-F153 AromaticContact CD1-CG 3.61Å; F99-F153 HydrophobicContact CD1-CG 3.61Å; F99-F153 HydrophobicContact CD1-CZ 4.14Å; F99-F153 HydrophobicContact CD2-CD2 4.01Å; F99-F153 HydrophobicContact CD2-CE2 4.3Å; F99-F153 HydrophobicContact CD2-CG 4.45Å; F99-F153 HydrophobicContact CE1-CB 3.3Å; F99-F153 AromaticContact CE1-CD1 3.59Å; F99-F153 HydrophobicContact CE1-CD1 3.59Å; F99-F153 AromaticContact CE1-CD2 3.86Å; F99-F153 HydrophobicContact CE1-CD2 3.86Å; F99-F153 HydrophobicContact CE1-CE1 4.31Å; F99-F153 AromaticContact CE1-CG 3.31Å; F99-F153 HydrophobicContact CE1-CG 3.31Å; F99-F153 HydrophobicContact CE2-CB 4.11Å; F99-F153 AromaticContact CE2-CD2 3.95Å; F99-F153 HydrophobicContact CE2-CD2 3.95Å; F99-F153 HydrophobicContact CE2-CG 4.17Å; F99-F153 HydrophobicContact CG-CD1 4.46Å; F99-F153 AromaticContact CG-CD2 4Å; F99-F153 HydrophobicContact CG-CD2 4Å; F99-F153 HydrophobicContact CG-CE1 4.47Å; F99-F153 HydrophobicContact CG-CE2 4.04Å; F99-F153 HydrophobicContact CG-CG 4.22Å; F99-F153 HydrophobicContact CG-CZ 4.29Å; F99-F153 HydrophobicContact CZ-CB 3.31Å; F99-F153 HydrophobicContact CZ-CD1 4.38Å; F99-F153 AromaticContact CZ-CD2 3.91Å; F99-F153 HydrophobicContact CZ-CD2 3.91Å; F99-F153 AromaticContact CZ-CG 3.64Å; F99-F153 HydrophobicContact CZ-CG 3.64Å; F111-F153 HydrophobicContact CB-CE1 4.36Å; F111-F153 AromaticContact CD2-CD1 3.88Å; F111-F153 HydrophobicContact CD2-CD1 3.88Å; F111-F153 AromaticContact CD2-CE1 3.92Å; F111-F153 HydrophobicContact CD2-CE1 3.92Å; S149-F153 WeakPolarHBondContact O-CB 3.5Å; S149-F153 PolarHBondContact O-N 3.39Å; V150-F153 PolarHBondContact O-N 3.45Å; K151-F153 VanDerWaalsContact C-N 3.33Å; K151-F153 PolarHBondContact O-N 3.27Å; F153-K155 VanDerWaalsContact C-N 3.33Å; F153-K155 PolarHBondContact O-N 3.09Å; F153-T156 PolarHBondContact O-N 2.68Å; F153-H157 AromaticContact CD2-CE1 3.5Å; F153-H157 AromaticContact CD2-ND1 3.82Å; F153-H157 AromaticContact CE2-CE1 3.25Å; F153-H157 WeakPolarHBondContact CE2-CE1 3.5Å; F153-H157 AromaticContact CE2-ND1 3.85Å; F153-H157 AromaticContact CE2-NE2 3.98Å; F153-H157 AromaticContact CZ-CE1 3.74Å; F153-H157 PolarHBondContact O-N 3.23Å; F153-H157 PolarHBondContact O-ND1 3.34Å; F153-F160 HydrophobicContact CD1-CE2 4.21Å; F153-F160 AromaticContact CD1-CZ 3.97Å; F153-F160 HydrophobicContact CD1-CZ 3.97Å; F153-F160 AromaticContact CE1-CE2 3.97Å; F153-F160 HydrophobicContact CE1-CE2 3.97Å; F153-F160 AromaticContact CE1-CZ 3.44Å; F153-F160 HydrophobicContact CE1-CZ 3.44Å; F153-F160 VanDerWaalsContact CE1-CZ 3.44Å; F153-F160 HydrophobicContact CZ-CZ 4.09Å
154F98.1Very high96Very high0 Ų064.8 Ų64.80%035%0.347CS..Hα-helixtrans-61.2-42.6174.5-84-79.3000111.8F111 W138 I140 V150 H157 D158 Y159 F160 M167 F169F111-F154 HydrophobicContact CB-CE1 4.38Å; F111-F154 HydrophobicContact CB-CE2 4.43Å; F111-F154 HydrophobicContact CB-CZ 3.84Å; F111-F154 HydrophobicContact CD1-CE2 4.04Å; F111-F154 AromaticContact CD1-CZ 3.83Å; F111-F154 HydrophobicContact CD1-CZ 3.83Å; F111-F154 HydrophobicContact CD2-CE2 4.06Å; F111-F154 HydrophobicContact CD2-CZ 4.3Å; F111-F154 HydrophobicContact CE1-CE2 4.25Å; F111-F154 HydrophobicContact CE1-CZ 4.44Å; F111-F154 HydrophobicContact CE2-CE2 4.27Å; F111-F154 AromaticContact CG-CE2 3.95Å; F111-F154 HydrophobicContact CG-CE2 3.95Å; F111-F154 AromaticContact CG-CZ 3.76Å; F111-F154 HydrophobicContact CG-CZ 3.76Å; F111-F154 HydrophobicContact CZ-CE2 4.36Å; W138-F154 HydrophobicContact CH2-CE1 4.39Å; W138-F154 HydrophobicContact CH2-CZ 4.22Å; W138-F154 HydrophobicContact CZ3-CE1 4.06Å; W138-F154 HydrophobicContact CZ3-CZ 4.25Å; I140-F154 HydrophobicContact CD1-CD2 4.34Å; I140-F154 HydrophobicContact CD1-CE1 4.48Å; I140-F154 HydrophobicContact CD1-CE2 3.46Å; I140-F154 VanDerWaalsContact CD1-CE2 3.46Å; I140-F154 HydrophobicContact CD1-CZ 3.54Å; V150-F154 HydrophobicContact CG1-CD2 3.97Å; V150-F154 HydrophobicContact CG1-CE2 3.94Å; V150-F154 WeakPolarHBondContact O-CD2 3.42Å; V150-F154 PolarHBondContact O-N 3.36Å; V150-F154 VanDerWaalsContact O-N 3.11Å; F154-H157 CarbonylContact O-C 3.6Å; F154-H157 PolarHBondContact O-N 2.85Å; F154-D158 PolarHBondContact O-N 3.19Å; F154-Y159 HydrophobicContact CB-CD1 3.86Å; F154-Y159 HydrophobicContact CB-CE1 4.18Å; F154-Y159 WeakPolarHBondContact O-CA 3.3Å; F154-Y159 PolarHBondContact O-N 3.33Å; F154-F160 AromaticContact CD1-CD2 3.69Å; F154-F160 HydrophobicContact CD1-CD2 3.69Å; F154-F160 AromaticContact CD1-CE2 3.71Å; F154-F160 HydrophobicContact CD1-CE2 3.71Å; F154-F160 AromaticContact CE1-CD2 3.64Å; F154-F160 HydrophobicContact CE1-CD2 3.64Å; F154-F160 AromaticContact CE1-CE2 3.74Å; F154-F160 HydrophobicContact CE1-CE2 3.74Å; F154-F160 HydrophobicContact CG-CE2 4.44Å; F154-F160 HydrophobicContact CZ-CE2 4.47Å; F154-M167 HydrophobicContact CD1-CE 3.51Å; F154-M167 HydrophobicContact CD1-SD 3.87Å; F154-M167 HydrophobicContact CD2-CE 4.04Å; F154-M167 HydrophobicContact CE1-CE 3.39Å; F154-M167 HydrophobicContact CE1-SD 4.16Å; F154-M167 HydrophobicContact CE2-CE 3.96Å; F154-M167 HydrophobicContact CG-CE 3.84Å; F154-M167 HydrophobicContact CG-SD 4.37Å; F154-M167 HydrophobicContact CZ-CE 3.63Å; F154-F169 HydrophobicContact CB-CZ 4.21Å; F154-F169 AromaticContact CD2-CE1 3.79Å; F154-F169 HydrophobicContact CD2-CE1 3.79Å; F154-F169 AromaticContact CD2-CZ 3.82Å; F154-F169 HydrophobicContact CD2-CZ 3.82Å; F154-F169 HydrophobicContact CE2-CE1 4.18Å; F154-F169 HydrophobicContact CE2-CZ 4.48Å; F154-F169 HydrophobicContact CG-CZ 4.11Å
155K97.8Very high96.3Very high145 Ų14562.4 Ų62.463%0.6335%0.345SS*.Hα-helixtrans-63.4-43.9178.6-173.2178.3178.9-177.80112.6K151 A152 F153 H157 D158K151-K155 PolarHBondContact O-N 3.06Å; K151-K155 VanDerWaalsContact O-N 3.1Å; A152-K155 PolarHBondContact O-N 3.18Å; F153-K155 VanDerWaalsContact C-N 3.33Å; F153-K155 PolarHBondContact O-N 3.09Å; K155-H157 PolarHBondContact O-N 3.17Å; K155-D158 PolarHBondContact O-N 2.97Å
156T97.9Very high96.9Very high110 Ų11057.7 Ų57.768%0.67532%0.32SS*.Hα-helixtrans-65.4-24.1-179.9-60.80000112.9A152 F153A152-T156 WeakPolarHBondContact O-CB 3.23Å; A152-T156 PolarHBondContact O-N 3.38Å; A152-T156 PolarHBondContact O-OG1 2.96Å; F153-T156 PolarHBondContact O-N 2.68Å
157H97.6Very high97.2Very high83 Ų8358.4 Ų58.438%0.38432%0.324SS..THydrogen-bonded Turntrans-10624178.1-60.683.2000112.5F153 F154 K155 Y159 F160F153-H157 AromaticContact CD2-CE1 3.5Å; F153-H157 AromaticContact CD2-ND1 3.82Å; F153-H157 AromaticContact CE2-CE1 3.25Å; F153-H157 WeakPolarHBondContact CE2-CE1 3.5Å; F153-H157 AromaticContact CE2-ND1 3.85Å; F153-H157 AromaticContact CE2-NE2 3.98Å; F153-H157 AromaticContact CZ-CE1 3.74Å; F153-H157 PolarHBondContact O-N 3.23Å; F153-H157 PolarHBondContact O-ND1 3.34Å; F154-H157 CarbonylContact O-C 3.6Å; F154-H157 PolarHBondContact O-N 2.85Å; K155-H157 PolarHBondContact O-N 3.17Å; H157-Y159 PolarHBondContact O-N 2.84Å; H157-F160 HydrophobicContact CB-CD1 3.83Å; H157-F160 HydrophobicContact CB-CE1 3.3Å; H157-F160 HydrophobicContact CB-CE2 4.29Å; H157-F160 HydrophobicContact CB-CG 4.49Å; H157-F160 HydrophobicContact CB-CZ 3.55Å; H157-F160 AromaticContact CD2-CE1 3.83Å; H157-F160 AromaticContact CG-CE1 3.58Å; H157-F160 AromaticContact CG-CZ 3.71Å; H157-F160 PolarHBondContact O-N 3.49Å
158D97.6Very high97.4Very high132 Ų13257 Ų5771%0.70632%0.318SS*.G310 helixtrans48.141.1179.9-63.9-45.7000113.3F154 K155 F160 G161F154-D158 PolarHBondContact O-N 3.19Å; K155-D158 PolarHBondContact O-N 2.97Å; D158-F160 PolarHBondContact O-N 2.79Å; D158-G161 PolarHBondContact O-N 2.82Å; D158-G161 VanDerWaalsContact O-N 3.11Å
159Y97.9Very high97.5Very high57 Ų5751.5 Ų51.522%0.22429%0.292CS..G310 helixtrans5523.9-179.2-56.9-92.5000113.8F154 H157 G161 L162 P164 M167F154-Y159 HydrophobicContact CB-CD1 3.86Å; F154-Y159 HydrophobicContact CB-CE1 4.18Å; F154-Y159 WeakPolarHBondContact O-CA 3.3Å; F154-Y159 PolarHBondContact O-N 3.33Å; H157-Y159 PolarHBondContact O-N 2.84Å; Y159-G161 PolarHBondContact O-N 3.43Å; Y159-L162 WeakPolarHBondContact CB-O 3.23Å; Y159-L162 VanDerWaalsContact O-CB 3.28Å; Y159-L162 WeakPolarHBondContact O-CB 3.31Å; Y159-L162 WeakPolarHBondContact O-CG 3.39Å; Y159-L162 PolarHBondContact O-N 2.94Å; Y159-P164 HydrophobicContact CD2-CB 4.28Å; Y159-P164 HydrophobicContact CD2-CG 3.67Å; Y159-P164 HydrophobicContact CE1-CB 4.27Å; Y159-P164 HydrophobicContact CE2-CB 4Å; Y159-P164 HydrophobicContact CE2-CG 3.63Å; Y159-P164 HydrophobicContact CG-CG 4.23Å; Y159-M167 HydrophobicContact CD1-SD 3.59Å; Y159-M167 VanDerWaalsContact CD1-SD 3.59Å; Y159-M167 HydrophobicContact CE1-SD 4.45Å; Y159-M167 HydrophobicContact CG-SD 4.39Å
160F97.2Very high97.6Very high22 Ų2250.2 Ų50.210%0.09628%0.283CS..G310 helixtrans52.635.4-175.1-53-71.3000112.7F111 Q112 A115 L119 F153 F154 H157 D158 L162F111-F160 HydrophobicContact CB-CE2 4.13Å; Q112-F160 HydrophobicContact CB-CD1 3.7Å; Q112-F160 HydrophobicContact CB-CE1 3.77Å; Q112-F160 HydrophobicContact CB-CG 4.13Å; Q112-F160 HydrophobicContact CB-CZ 4.27Å; Q112-F160 HydrophobicContact CG-CB 4.5Å; Q112-F160 HydrophobicContact CG-CD1 3.62Å; Q112-F160 HydrophobicContact CG-CE1 4.09Å; Q112-F160 HydrophobicContact CG-CG 4.16Å; A115-F160 HydrophobicContact CB-CB 3.73Å; A115-F160 HydrophobicContact CB-CD2 4.22Å; A115-F160 HydrophobicContact CB-CG 4.3Å; L119-F160 VanDerWaalsContact CD1-O 3.29Å; L119-F160 WeakPolarHBondContact CD1-O 3.41Å; F153-F160 HydrophobicContact CD1-CE2 4.21Å; F153-F160 AromaticContact CD1-CZ 3.97Å; F153-F160 HydrophobicContact CD1-CZ 3.97Å; F153-F160 AromaticContact CE1-CE2 3.97Å; F153-F160 HydrophobicContact CE1-CE2 3.97Å; F153-F160 AromaticContact CE1-CZ 3.44Å; F153-F160 HydrophobicContact CE1-CZ 3.44Å; F153-F160 VanDerWaalsContact CE1-CZ 3.44Å; F153-F160 HydrophobicContact CZ-CZ 4.09Å; F154-F160 AromaticContact CD1-CD2 3.69Å; F154-F160 HydrophobicContact CD1-CD2 3.69Å; F154-F160 AromaticContact CD1-CE2 3.71Å; F154-F160 HydrophobicContact CD1-CE2 3.71Å; F154-F160 AromaticContact CE1-CD2 3.64Å; F154-F160 HydrophobicContact CE1-CD2 3.64Å; F154-F160 AromaticContact CE1-CE2 3.74Å; F154-F160 HydrophobicContact CE1-CE2 3.74Å; F154-F160 HydrophobicContact CG-CE2 4.44Å; F154-F160 HydrophobicContact CZ-CE2 4.47Å; H157-F160 HydrophobicContact CB-CD1 3.83Å; H157-F160 HydrophobicContact CB-CE1 3.3Å; H157-F160 HydrophobicContact CB-CE2 4.29Å; H157-F160 HydrophobicContact CB-CG 4.49Å; H157-F160 HydrophobicContact CB-CZ 3.55Å; H157-F160 AromaticContact CD2-CE1 3.83Å; H157-F160 AromaticContact CG-CE1 3.58Å; H157-F160 AromaticContact CG-CZ 3.71Å; H157-F160 PolarHBondContact O-N 3.49Å; D158-F160 PolarHBondContact O-N 2.79Å; F160-L162 VanDerWaalsContact C-N 3.31Å; F160-L162 PolarHBondContact O-N 2.63Å
161G96.6Very high97.6Very high59 Ų5950.9 Ų50.961%0.60829%0.287SS*.G310 helixtrans83.7-3-178.900000115D158 Y159D158-G161 PolarHBondContact O-N 2.82Å; D158-G161 VanDerWaalsContact O-N 3.11Å; Y159-G161 PolarHBondContact O-N 3.43Å
162L98Very high97.5Very high5 Ų547.7 Ų47.73%0.02627%0.273CS..  trans-73.7141.2173-62.7169.1000110.8A115 L118 L119 W138 Y159 F160 P164 Q166 M167A115-L162 HydrophobicContact CB-CD1 3.69Å; A115-L162 HydrophobicContact CB-CG 4.24Å; L118-L162 HydrophobicContact CB-CD2 4.34Å; L119-L162 HydrophobicContact CD1-CD2 4.49Å; L119-L162 HydrophobicContact CD2-CD2 3.71Å; L119-L162 HydrophobicContact CD2-CG 4.47Å; L119-L162 HydrophobicContact CG-CD2 3.69Å; L119-L162 HydrophobicContact CG-CG 4.38Å; W138-L162 HydrophobicContact CE3-CD1 3.41Å; W138-L162 VanDerWaalsContact CE3-CD1 3.41Å; W138-L162 HydrophobicContact CZ3-CD1 3.43Å; W138-L162 VanDerWaalsContact CZ3-CD1 3.43Å; Y159-L162 WeakPolarHBondContact CB-O 3.23Å; Y159-L162 VanDerWaalsContact O-CB 3.28Å; Y159-L162 WeakPolarHBondContact O-CB 3.31Å; Y159-L162 WeakPolarHBondContact O-CG 3.39Å; Y159-L162 PolarHBondContact O-N 2.94Å; F160-L162 VanDerWaalsContact C-N 3.31Å; F160-L162 PolarHBondContact O-N 2.63Å; L162-P164 WeakPolarHBondContact O-CD 3.47Å; L162-Q166 HydrophobicContact CB-CG 4.41Å; L162-M167 HydrophobicContact CD1-SD 4.2Å
163S97.7Very high97.3Very high43 Ų4346.7 Ų46.730%0.30126%0.264SS..  trans-56.4125.4164.3-1790000111N135 S165 Q166N135-S163 WeakPolarHBondContact ND2-CB 3.38Å; S163-S165 PolarHBondContact O-N 3.1Å; S163-S165 VanDerWaalsContact O-N 3.09Å; S163-S165 PolarHBondContact OG-OG 3.37Å; S163-Q166 VanDerWaalsContact O-CG 3.23Å; S163-Q166 WeakPolarHBondContact O-CG 3.2Å; S163-Q166 PolarHBondContact O-N 2.74Å; S163-Q166 PolarHBondContact O-NE2 2.87Å
164P97.7Very high97.1Very high71 Ų7147 Ų4746%0.46127%0.267SS..G310 helixtrans-55-32.5178-25.732.7000113.3Y159 L162 Q166 M167Y159-P164 HydrophobicContact CD2-CB 4.28Å; Y159-P164 HydrophobicContact CD2-CG 3.67Å; Y159-P164 HydrophobicContact CE1-CB 4.27Å; Y159-P164 HydrophobicContact CE2-CB 4Å; Y159-P164 HydrophobicContact CE2-CG 3.63Å; Y159-P164 HydrophobicContact CG-CG 4.23Å; L162-P164 WeakPolarHBondContact O-CD 3.47Å; P164-Q166 PolarHBondContact O-N 2.94Å; P164-M167 PolarHBondContact O-N 3.25Å; P164-M167 VanDerWaalsContact O-N 3.14Å
165S96.8Very high96.8Very high85 Ų8548.8 Ų48.859%0.59428%0.276SS*.G310 helixtrans-69.5-11.6179.664.30000115.1S163S163-S165 PolarHBondContact O-N 3.1Å; S163-S165 VanDerWaalsContact O-N 3.09Å; S163-S165 PolarHBondContact OG-OG 3.37Å
166Q97.5Very high96.6Very high4 Ų443.6 Ų43.62%0.01926%0.257CS..G310 helixtrans-89-11.5174.190.8-167.3-9700112.4N135 I136 T137 W138 L162 S163 P164N135-Q166 HydrophobicContact CB-CB 3.72Å; N135-Q166 HydrophobicContact CB-CG 4.4Å; I136-Q166 PolarHBondContact O-OE1 3.32Å; T137-Q166 WeakPolarHBondContact CA-O 3.38Å; W138-Q166 PolarHBondContact N-O 3.34Å; L162-Q166 HydrophobicContact CB-CG 4.41Å; S163-Q166 VanDerWaalsContact O-CG 3.23Å; S163-Q166 WeakPolarHBondContact O-CG 3.2Å; S163-Q166 PolarHBondContact O-N 2.74Å; S163-Q166 PolarHBondContact O-NE2 2.87Å; P164-Q166 PolarHBondContact O-N 2.94Å
167M98.3Very high96.4Very high15 Ų1538.5 Ų38.57%0.07423%0.226CC..EExtended strand (participates in β ladder)trans-99.2131-177-63.2-16673.400111.4W138 I140 F154 Y159 L162 P164 F169W138-M167 HydrophobicContact CE3-CE 4.03Å; W138-M167 HydrophobicContact CZ3-CE 4.44Å; W138-M167 WeakPolarHBondContact O-CA 3.48Å; I140-M167 HydrophobicContact CD1-CE 3.36Å; I140-M167 HydrophobicContact CG1-CE 4.36Å; F154-M167 HydrophobicContact CD1-CE 3.51Å; F154-M167 HydrophobicContact CD1-SD 3.87Å; F154-M167 HydrophobicContact CD2-CE 4.04Å; F154-M167 HydrophobicContact CE1-CE 3.39Å; F154-M167 HydrophobicContact CE1-SD 4.16Å; F154-M167 HydrophobicContact CE2-CE 3.96Å; F154-M167 HydrophobicContact CG-CE 3.84Å; F154-M167 HydrophobicContact CG-SD 4.37Å; F154-M167 HydrophobicContact CZ-CE 3.63Å; Y159-M167 HydrophobicContact CD1-SD 3.59Å; Y159-M167 VanDerWaalsContact CD1-SD 3.59Å; Y159-M167 HydrophobicContact CE1-SD 4.45Å; Y159-M167 HydrophobicContact CG-SD 4.39Å; L162-M167 HydrophobicContact CD1-SD 4.2Å; P164-M167 PolarHBondContact O-N 3.25Å; P164-M167 VanDerWaalsContact O-N 3.14Å; M167-F169 HydrophobicContact CB-CE2 4.09Å; M167-F169 HydrophobicContact CB-CZ 4.48Å; M167-F169 HydrophobicContact CE-CE1 4.19Å; M167-F169 HydrophobicContact CE-CE2 4.36Å; M167-F169 HydrophobicContact CE-CZ 3.63Å; M167-F169 HydrophobicContact SD-CZ 4.38Å
168I98.3Very high96.3Very high31 Ų3137 Ų3716%0.15922%0.218CC..EExtended strand (participates in β ladder)trans-124.5112.1177.6-58.8173.2000107.9T137 W138 C139 I140 V211 V214T137-I168 HydrophobicContact CG2-CD1 3.62Å; T137-I168 HydrophobicContact CG2-CG1 4.26Å; W138-I168 PolarHBondContact O-N 2.84Å; C139-I168 CarbonylContact C-O 3.43Å; C139-I168 WeakPolarHBondContact CA-O 3.14Å; C139-I168 HydrophobicContact CB-CB 4.46Å; I140-I168 PolarHBondContact N-O 2.9Å; I168-V211 HydrophobicContact CG2-CG2 4.23Å; I168-V214 HydrophobicContact CD1-CB 4.29Å; I168-V214 HydrophobicContact CD1-CG1 3.51Å
169F98.1Very high96Very high41 Ų4132.7 Ų32.718%0.1820%0.195CC..EExtended strand (participates in β ladder)trans-93.9132.4173.7-60.1-87.3000109.1I140 V150 K151 F154 M167I140-F169 HydrophobicContact CB-CD1 3.98Å; I140-F169 HydrophobicContact CB-CE1 4.22Å; I140-F169 HydrophobicContact CD1-CD1 4.47Å; I140-F169 HydrophobicContact CD1-CE1 3.84Å; I140-F169 HydrophobicContact CD1-CZ 4.44Å; I140-F169 HydrophobicContact CG1-CE1 4.44Å; I140-F169 HydrophobicContact CG2-CD1 4.38Å; V150-F169 HydrophobicContact CG1-CD1 4.2Å; V150-F169 HydrophobicContact CG1-CE1 3.82Å; K151-F169 HydrophobicContact CD-CB 4.42Å; K151-F169 HydrophobicContact CD-CG 4.45Å; K151-F169 HydrophobicContact CG-CB 4.25Å; K151-F169 HydrophobicContact CG-CD1 3.95Å; K151-F169 HydrophobicContact CG-CD2 4.05Å; K151-F169 HydrophobicContact CG-CE1 4.32Å; K151-F169 HydrophobicContact CG-CE2 4.41Å; K151-F169 HydrophobicContact CG-CG 3.81Å; F154-F169 HydrophobicContact CB-CZ 4.21Å; F154-F169 AromaticContact CD2-CE1 3.79Å; F154-F169 HydrophobicContact CD2-CE1 3.79Å; F154-F169 AromaticContact CD2-CZ 3.82Å; F154-F169 HydrophobicContact CD2-CZ 3.82Å; F154-F169 HydrophobicContact CE2-CE1 4.18Å; F154-F169 HydrophobicContact CE2-CZ 4.48Å; F154-F169 HydrophobicContact CG-CZ 4.11Å; M167-F169 HydrophobicContact CB-CE2 4.09Å; M167-F169 HydrophobicContact CB-CZ 4.48Å; M167-F169 HydrophobicContact CE-CE1 4.19Å; M167-F169 HydrophobicContact CE-CE2 4.36Å; M167-F169 HydrophobicContact CE-CZ 3.63Å; M167-F169 HydrophobicContact SD-CZ 4.38Å
170F98.1Very high95.7Very high2 Ų234.4 Ų34.41%0.00921%0.208CC..EExtended strand (participates in β ladder)trans-144.915217870.7-77.5000109.8I81 C139 I140 M141 T142 L202 A205 L206 E209 V211I81-F170 HydrophobicContact CG2-CE1 4.22Å; I81-F170 HydrophobicContact CG2-CZ 3.94Å; C139-F170 HydrophobicContact CB-CD1 4.22Å; C139-F170 HydrophobicContact CB-CE1 3.73Å; I140-F170 WeakPolarHBondContact O-CD1 3.34Å; I140-F170 PolarHBondContact O-N 3.06Å; I140-F170 VanDerWaalsContact O-N 3.08Å; M141-F170 CarbonylContact C-O 3.56Å; M141-F170 WeakPolarHBondContact CA-O 3.15Å; M141-F170 HydrophobicContact CB-CE1 3.85Å; M141-F170 HydrophobicContact CB-CE2 3.81Å; M141-F170 HydrophobicContact CB-CZ 3.44Å; M141-F170 VanDerWaalsContact CB-CZ 3.44Å; M141-F170 HydrophobicContact CG-CD2 4.18Å; M141-F170 HydrophobicContact CG-CE2 3.59Å; M141-F170 HydrophobicContact CG-CZ 3.79Å; M141-F170 HydrophobicContact SD-CE2 3.95Å; M141-F170 HydrophobicContact SD-CZ 4.25Å; T142-F170 PolarHBondContact N-O 2.83Å; T142-F170 PolarHBondContact OG1-O 3.41Å; F170-L202 HydrophobicContact CE2-CD1 3.98Å; F170-L202 HydrophobicContact CZ-CD1 3.75Å; F170-A205 HydrophobicContact CD2-CB 3.91Å; F170-A205 HydrophobicContact CE2-CB 3.95Å; F170-L206 HydrophobicContact CE2-CD2 3.98Å; F170-L206 HydrophobicContact CE2-CG 4.28Å; F170-L206 HydrophobicContact CZ-CD2 3.87Å; F170-L206 HydrophobicContact CZ-CG 4.48Å; F170-E209 HydrophobicContact CB-CB 3.91Å; F170-E209 HydrophobicContact CB-CG 4.06Å; F170-V211 HydrophobicContact CB-CG2 3.76Å; F170-V211 HydrophobicContact CD1-CG2 4.06Å; F170-V211 HydrophobicContact CD2-CG2 4.17Å; F170-V211 HydrophobicContact CG-CG2 3.74Å
171T96.8Very high95.5Very high14 Ų1439.5 Ų39.59%0.08624%0.237CC..EExtended strand (participates in β ladder)trans-114.5132.5-168.5-69.70000111.5T142 Q144 E147T142-T171 WeakPolarHBondContact O-CA 3.48Å; T142-T171 PolarHBondContact OG1-OG1 3.23Å; T142-T171 VanDerWaalsContact OG1-OG1 3.1Å; Q144-T171 HydrophobicContact CG-CG2 4.1Å; E147-T171 PolarHBondContact OE2-OG1 3.28Å
172Q95.3Very high95.1Very high10 Ų1039.1 Ų39.15%0.04723%0.233CC..  trans-73.4157.4174.872177.5107.300112.3M141 T142 P196 D197 G198M141-Q172 HydrophobicContact CE-CB 4.48Å; M141-Q172 HydrophobicContact CG-CB 4.15Å; M141-Q172 HydrophobicContact SD-CB 4.07Å; T142-Q172 WeakPolarHBondContact O-CG 3.04Å; T142-Q172 PolarHBondContact O-N 3.42Å; Q172-P196 HydrophobicContact CG-CB 4.33Å; Q172-D197 PolarHBondContact NE2-OD1 2.52Å; Q172-G198 PolarHBondContact NE2-O 2.87Å
173S93.2Very high94.9Very high17 Ų1745.4 Ų45.412%0.11926%0.26CS..  trans-68.4161177.1-730000111.8D197 E204S173-D197 PolarHBondContact O-N 3.49Å; S173-E204 PolarHBondContact OG-OE1 3.03Å
174L92.1Very high94.7Very high41 Ų4146.5 Ų46.522%0.21527%0.265CS..EExtended strand (participates in β ladder)trans-108.9149.8172.6-63.1178.9000109.5Q144 V194 A195 P196Q144-L174 HydrophobicContact CB-CD1 4.29Å; Q144-L174 HydrophobicContact CG-CD1 4Å; Q144-L174 HydrophobicContact CG-CG 4.4Å; L174-V194 HydrophobicContact CB-CB 4.24Å; L174-V194 HydrophobicContact CD1-CB 4.3Å; L174-V194 HydrophobicContact CD1-CG2 3.78Å; L174-A195 CarbonylContact C-O 3.46Å; L174-A195 WeakPolarHBondContact CA-O 3.31Å; L174-P196 HydrophobicContact CD2-CG 4.33Å
175M92.9Very high94.5Very high38 Ų3843.6 Ų43.619%0.18725%0.245CC..EExtended strand (participates in β ladder)trans-118.1142.6171.5-74.6-62.1-65.600110.8V194 A195 D197 Y326 L353M175-V194 CarbonylContact O-C 3.43Å; M175-V194 WeakPolarHBondContact O-CA 3.38Å; M175-A195 PolarHBondContact N-O 2.67Å; M175-A195 PolarHBondContact O-N 2.95Å; M175-D197 HydrophobicContact CB-CB 4.49Å; M175-D197 HydrophobicContact CG-CB 3.62Å; M175-Y326 HydrophobicContact CE-CE1 3.9Å; M175-Y326 HydrophobicContact CG-CE1 3.99Å; M175-Y326 HydrophobicContact SD-CE1 4.01Å; M175-L353 HydrophobicContact CE-CD1 3.95Å
176P93.4Very high94.3Very high36 Ų3643.4 Ų43.423%0.23424%0.237CC..EExtended strand (participates in β ladder)trans-57.8144.6168.9-22.533.3000111.6F178 V184 I192P176-F178 HydrophobicContact CB-CE2 4.09Å; P176-F178 HydrophobicContact CB-CZ 3.93Å; P176-F178 HydrophobicContact CG-CZ 4.44Å; P176-F178 WeakPolarHBondContact O-CD2 3.2Å; P176-F178 WeakPolarHBondContact O-CE2 3.4Å; P176-V184 HydrophobicContact CB-CG1 4.25Å; P176-V184 HydrophobicContact CB-CG2 4.26Å; P176-I192 HydrophobicContact CB-CD1 4.32Å; P176-I192 HydrophobicContact CG-CD1 4.2Å
177C93.3Very high94Very high2 Ų245.3 Ų45.31%0.01425%0.247CC..  trans-86.3142.2166.9-65.40000109.8V184 I185 A193 I333C177-V184 WeakPolarHBondContact O-CA 3.3Å; C177-I185 HydrophobicContact CB-CD1 4.42Å; C177-I185 PolarHBondContact O-N 2.98Å; C177-A193 HydrophobicContact CB-CB 4.02Å; C177-A193 WeakPolarHBondContact CB-O 3.44Å; C177-A193 PolarHBondContact N-O 3.23Å; C177-I333 HydrophobicContact CB-CD1 4.05Å; C177-I333 HydrophobicContact CB-CG2 3.91Å
178F95Very high93.7Very high51 Ų5146 Ų4622%0.22426%0.256CS..EExtended strand (participates in β ladder)trans-119.2144-177.3-60.2-88.5000111.4P176 K183 V184 G350 F351 L353P176-F178 HydrophobicContact CB-CE2 4.09Å; P176-F178 HydrophobicContact CB-CZ 3.93Å; P176-F178 HydrophobicContact CG-CZ 4.44Å; P176-F178 WeakPolarHBondContact O-CD2 3.2Å; P176-F178 WeakPolarHBondContact O-CE2 3.4Å; F178-K183 CarbonylContact C-O 3.47Å; F178-K183 VanDerWaalsContact CA-O 3.23Å; F178-K183 WeakPolarHBondContact CA-O 3.49Å; F178-V184 HydrophobicContact CD1-CG2 4.14Å; F178-V184 HydrophobicContact CE1-CG2 3.74Å; F178-G350 CarbonylContact O-C 3.38Å; F178-G350 WeakPolarHBondContact O-CA 3.44Å; F178-F351 PolarHBondContact N-O 2.92Å; F178-F351 PolarHBondContact O-N 3.18Å; F178-L353 HydrophobicContact CD2-CD1 4.16Å; F178-L353 HydrophobicContact CD2-CG 4.34Å; F178-L353 HydrophobicContact CE2-CD1 3.69Å; F178-L353 HydrophobicContact CE2-CG 4.27Å
179D92.4Very high93.3Very high42 Ų4254.1 Ų54.123%0.22528%0.284CS..EExtended strand (participates in β ladder)trans-75.3-179.5171.777.4-1.9000111.8N181 G182 K183 I185D179-N181 PolarHBondContact O-N 3.06Å; D179-N181 VanDerWaalsContact O-N 3.11Å; D179-N181 VanDerWaalsContact OD1-C 3.3Å; D179-N181 VanDerWaalsContact OD1-CA 3.29Å; D179-N181 WeakPolarHBondContact OD1-CA 3.18Å; D179-N181 WeakPolarHBondContact OD1-CB 3.4Å; D179-N181 PolarHBondContact OD1-N 2.83Å; D179-G182 PolarHBondContact O-N 2.67Å; D179-G182 VanDerWaalsContact O-N 3.09Å; D179-G182 PolarHBondContact OD1-N 2.88Å; D179-K183 PolarHBondContact N-O 3.41Å; D179-K183 PolarHBondContact OD1-N 2.62Å; D179-I185 HydrophobicContact CB-CD1 4.32Å; D179-I185 HydrophobicContact CB-CG1 4Å
180N91.3Very high93Very high93 Ų9359.2 Ų59.250%0.49731%0.313SS..THydrogen-bonded Turntrans-64.2-12.4178.4-70.4-36.9000114.7N349N180-N349 PolarHBondContact N-O 3.3Å
181N92.2Very high92.6Very high129 Ų12963.3 Ų63.369%0.6933%0.332SS*.THydrogen-bonded Turntrans-101.96.8177.7-55.2-55.2000112.5D179 K183D179-N181 PolarHBondContact O-N 3.06Å; D179-N181 VanDerWaalsContact O-N 3.11Å; D179-N181 VanDerWaalsContact OD1-C 3.3Å; D179-N181 VanDerWaalsContact OD1-CA 3.29Å; D179-N181 WeakPolarHBondContact OD1-CA 3.18Å; D179-N181 WeakPolarHBondContact OD1-CB 3.4Å; D179-N181 PolarHBondContact OD1-N 2.83Å; N181-K183 VanDerWaalsContact C-N 3.3Å; N181-K183 HydrophobicContact CB-CG 4.22Å; N181-K183 PolarHBondContact O-N 3.39Å
182G89.5Confident92.5Very high51 Ų5166 Ų6653%0.52635%0.345SS..SBendtrans72.120.6-177.200000113.8D179D179-G182 PolarHBondContact O-N 2.67Å; D179-G182 VanDerWaalsContact O-N 3.09Å; D179-G182 PolarHBondContact OD1-N 2.88Å
183K92.7Very high92.3Very high137 Ų13765.7 Ų65.760%0.59635%0.345SS*.PPolyproline II helixtrans-95.6145.5175.6-53.3-55.1179.6-174.20110.2F178 D179 N181 I185F178-K183 CarbonylContact C-O 3.47Å; F178-K183 VanDerWaalsContact CA-O 3.23Å; F178-K183 WeakPolarHBondContact CA-O 3.49Å; D179-K183 PolarHBondContact N-O 3.41Å; D179-K183 PolarHBondContact OD1-N 2.62Å; N181-K183 VanDerWaalsContact C-N 3.3Å; N181-K183 HydrophobicContact CB-CG 4.22Å; N181-K183 PolarHBondContact O-N 3.39Å; K183-I185 PolarHBondContact O-N 2.85Å
184V94.5Very high92.2Very high67 Ų6767.2 Ų67.241%0.40635%0.353SS..BIsolated β-bridgetrans-64.2136.2178.1178.80000109.6P176 C177 F178 I192P176-V184 HydrophobicContact CB-CG1 4.25Å; P176-V184 HydrophobicContact CB-CG2 4.26Å; C177-V184 WeakPolarHBondContact O-CA 3.3Å; F178-V184 HydrophobicContact CD1-CG2 4.14Å; F178-V184 HydrophobicContact CE1-CG2 3.74Å; V184-I192 HydrophobicContact CG1-CB 3.73Å; V184-I192 HydrophobicContact CG1-CD1 4.34Å; V184-I192 HydrophobicContact CG1-CG2 3.55Å
185I91.9Very high92.1Very high10 Ų1065.5 Ų65.55%0.05135%0.345CS..PPolyproline II helixtrans-84.8132.7175.2-64.8171.8000109C177 D179 K183 I192 A193 I333 F335C177-I185 HydrophobicContact CB-CD1 4.42Å; C177-I185 PolarHBondContact O-N 2.98Å; D179-I185 HydrophobicContact CB-CD1 4.32Å; D179-I185 HydrophobicContact CB-CG1 4Å; K183-I185 PolarHBondContact O-N 2.85Å; I185-I192 WeakPolarHBondContact O-CA 3.44Å; I185-A193 HydrophobicContact CB-CB 4.06Å; I185-A193 HydrophobicContact CG2-CB 3.87Å; I185-A193 PolarHBondContact O-N 2.78Å; I185-I333 HydrophobicContact CD1-CB 4.03Å; I185-I333 HydrophobicContact CD1-CD1 4.09Å; I185-I333 HydrophobicContact CD1-CG2 3.84Å; I185-I333 HydrophobicContact CG2-CG2 4.21Å; I185-F335 HydrophobicContact CG2-CB 3.48Å; I185-F335 VanDerWaalsContact CG2-CB 3.48Å
186L94.5Very high92.1Very high80 Ų8065.1 Ų65.142%0.41935%0.346SS..EExtended strand (participates in β ladder)trans-89.8138.4164.9-69.5172.4000109.3H191 I192 F335 L336L186-H191 WeakPolarHBondContact CA-O 3.19Å; L186-H191 WeakPolarHBondContact CD2-O 3.23Å; L186-I192 HydrophobicContact CD2-CG2 3.73Å; L186-F335 CarbonylContact O-C 3.39Å; L186-F335 WeakPolarHBondContact O-CA 3.44Å; L186-L336 HydrophobicContact CB-CB 4.11Å; L186-L336 PolarHBondContact O-N 3.42Å
187D90.7Very high92Very high44 Ų4463.5 Ų63.524%0.23534%0.335CS..EExtended strand (participates in β ladder)trans-113.2-11168.361.4-4000112.3H191 A193 L342D187-H191 VanDerWaalsContact CG-ND1 3.3Å; D187-H191 PolarHBondContact N-O 3.45Å; D187-H191 VanDerWaalsContact N-O 3.15Å; D187-H191 WeakPolarHBondContact OD1-CB 3.45Å; D187-H191 IonicContact OD1-CE1 2.94Å; D187-H191 IonicContact OD1-CG 2.74Å; D187-H191 IonicContact OD1-ND1 3.6Å; D187-H191 PolarHBondContact OD1-ND1 3.1Å; D187-H191 IonicContact OD2-CE1 2.74Å; D187-H191 IonicContact OD2-ND1 2.64Å; D187-H191 PolarHBondContact OD2-ND1 3.33Å; D187-A193 HydrophobicContact CB-CB 4.12Å; D187-L342 HydrophobicContact CB-CD1 4.16Å; D187-L342 WeakPolarHBondContact O-CD1 3.44Å
188A90.7Very high92Very high31 Ų3163.8 Ų63.826%0.25634%0.339SS..EExtended strand (participates in β ladder)trans-141.2172.516300000110.5D190 H191A188-D190 PolarHBondContact O-N 3.23Å; A188-H191 HydrophobicContact CB-CB 3.78Å; A188-H191 PolarHBondContact N-O 3.21Å; A188-H191 PolarHBondContact O-N 3.31Å; A188-H191 VanDerWaalsContact O-O 3.12Å
189R89.9Confident91.9Very high200 Ų20063.6 Ų63.676%0.75534%0.34SS*.THydrogen-bonded Turntrans-63.2-23.4180-68.9-178.9179.2-168.5-2.5112.9L336R189-L336 HydrophobicContact CG-CD2 3.96Å
190D92.1Very high92Very high148 Ų14861.7 Ų61.779%0.79133%0.33SS*.THydrogen-bonded Turntrans-124.89.3-17561-25.7000112.7A188A188-D190 PolarHBondContact O-N 3.23Å
191H90.9Very high92.1Very high88 Ų8857.2 Ų57.241%0.40731%0.306SS..EExtended strand (participates in β ladder)trans-136.7131.5-175.8-168.9-100.1000111.5L186 D187 A188L186-H191 WeakPolarHBondContact CA-O 3.19Å; L186-H191 WeakPolarHBondContact CD2-O 3.23Å; D187-H191 VanDerWaalsContact CG-ND1 3.3Å; D187-H191 PolarHBondContact N-O 3.45Å; D187-H191 VanDerWaalsContact N-O 3.15Å; D187-H191 WeakPolarHBondContact OD1-CB 3.45Å; D187-H191 IonicContact OD1-CE1 2.94Å; D187-H191 IonicContact OD1-CG 2.74Å; D187-H191 IonicContact OD1-ND1 3.6Å; D187-H191 PolarHBondContact OD1-ND1 3.1Å; D187-H191 IonicContact OD2-CE1 2.74Å; D187-H191 IonicContact OD2-ND1 2.64Å; D187-H191 PolarHBondContact OD2-ND1 3.33Å; A188-H191 HydrophobicContact CB-CB 3.78Å; A188-H191 PolarHBondContact N-O 3.21Å; A188-H191 PolarHBondContact O-N 3.31Å; A188-H191 VanDerWaalsContact O-O 3.12Å
192I93.8Very high92.3Very high70 Ų7051.1 Ų51.136%0.35927%0.273SS..EExtended strand (participates in β ladder)trans-87.4139.6171.154.8161.6000109.3P176 V184 I185 L186 V194P176-I192 HydrophobicContact CB-CD1 4.32Å; P176-I192 HydrophobicContact CG-CD1 4.2Å; V184-I192 HydrophobicContact CG1-CB 3.73Å; V184-I192 HydrophobicContact CG1-CD1 4.34Å; V184-I192 HydrophobicContact CG1-CG2 3.55Å; I185-I192 WeakPolarHBondContact O-CA 3.44Å; L186-I192 HydrophobicContact CD2-CG2 3.73Å; I192-V194 HydrophobicContact CD1-CG1 3.93Å; I192-V194 HydrophobicContact CG1-CG1 3.94Å; I192-V194 PolarHBondContact O-N 3.33Å
193A90.9Very high92.7Very high5 Ų549.1 Ų49.14%0.04125%0.25CS..  trans-64.4121.3172.300000109.2C177 I185 D187 I333C177-A193 HydrophobicContact CB-CB 4.02Å; C177-A193 WeakPolarHBondContact CB-O 3.44Å; C177-A193 PolarHBondContact N-O 3.23Å; I185-A193 HydrophobicContact CB-CB 4.06Å; I185-A193 HydrophobicContact CG2-CB 3.87Å; I185-A193 PolarHBondContact O-N 2.78Å; D187-A193 HydrophobicContact CB-CB 4.12Å; A193-I333 HydrophobicContact CB-CG2 3.98Å
194V92.5Very high92.7Very high48 Ų4846.4 Ų46.429%0.29124%0.24SC..EExtended strand (participates in β ladder)trans-124.3156-179.9-68.80000111L174 M175 I192L174-V194 HydrophobicContact CB-CB 4.24Å; L174-V194 HydrophobicContact CD1-CB 4.3Å; L174-V194 HydrophobicContact CD1-CG2 3.78Å; M175-V194 CarbonylContact O-C 3.43Å; M175-V194 WeakPolarHBondContact O-CA 3.38Å; I192-V194 HydrophobicContact CD1-CG1 3.93Å; I192-V194 HydrophobicContact CG1-CG1 3.94Å; I192-V194 PolarHBondContact O-N 3.33Å
195A89.9Confident92.8Very high6 Ų643.2 Ų43.25%0.0522%0.22CC..EExtended strand (participates in β ladder)trans-141.6156.7174.500000110.9L174 M175 D197 K352L174-A195 CarbonylContact C-O 3.46Å; L174-A195 WeakPolarHBondContact CA-O 3.31Å; M175-A195 PolarHBondContact N-O 2.67Å; M175-A195 PolarHBondContact O-N 2.95Å; A195-D197 PolarHBondContact O-N 3.11Å; A195-K352 HydrophobicContact CB-CD 3.61Å; A195-K352 HydrophobicContact CB-CG 4.17Å
196P92.1Very high93Very high30 Ų3042.8 Ų42.820%0.19522%0.218CC..EExtended strand (participates in β ladder)trans-53.9139.4171.1-2434.1000111.4Q172 L174 G198Q172-P196 HydrophobicContact CG-CB 4.33Å; L174-P196 HydrophobicContact CD2-CG 4.33Å; P196-G198 PolarHBondContact O-N 2.89Å
197D91.8Very high93Very high1 Ų143 Ų431%0.00522%0.215CC..  trans-77.223.7-175.772.5-29.4000114.5Q172 S173 M175 A195 G201 K355Q172-D197 PolarHBondContact NE2-OD1 2.52Å; S173-D197 PolarHBondContact O-N 3.49Å; M175-D197 HydrophobicContact CB-CB 4.49Å; M175-D197 HydrophobicContact CG-CB 3.62Å; A195-D197 PolarHBondContact O-N 3.11Å; D197-G201 WeakPolarHBondContact OD1-CA 3.26Å; D197-G201 WeakPolarHBondContact OD2-CA 3.47Å; D197-K355 PolarHBondContact O-N 3.28Å
198G92.1Very high93.2Very high9 Ų947.4 Ų47.49%0.09323%0.233CC..  trans82.4173.6-179.300000114.2Q172 P196 G200 G201 K355Q172-G198 PolarHBondContact NE2-O 2.87Å; P196-G198 PolarHBondContact O-N 2.89Å; G198-G200 PolarHBondContact O-N 2.89Å; G198-G201 PolarHBondContact O-N 2.64Å; G198-K355 CarbonylContact C-O 3.58Å
199N94.4Very high93.5Very high46 Ų4650.2 Ų50.225%0.24624%0.241CC..G310 helixtrans-72.6-17.4-178.962.516.5000113.2L83 G201 L202 K355 F356 I357L83-N199 HydrophobicContact CD1-CB 4.18Å; N199-G201 VanDerWaalsContact C-N 3.29Å; N199-L202 VanDerWaalsContact O-CB 3.31Å; N199-L202 WeakPolarHBondContact O-CB 3.31Å; N199-L202 PolarHBondContact O-N 3.31Å; N199-K355 PolarHBondContact N-O 2.8Å; N199-K355 PolarHBondContact OD1-O 2.79Å; N199-F356 VanDerWaalsContact OD1-CA 3.31Å; N199-F356 WeakPolarHBondContact OD1-CA 3.35Å; N199-I357 PolarHBondContact OD1-N 3.37Å
200G94.4Very high93.8Very high2 Ų241.8 Ų41.82%0.02122%0.216CC..G310 helixtrans-76.1-10.6171.300000114.3G198 L202 Y203 K355G198-G200 PolarHBondContact O-N 2.89Å; G200-L202 PolarHBondContact O-N 3.25Å; G200-L202 VanDerWaalsContact O-N 3.11Å; G200-Y203 WeakPolarHBondContact O-CD2 3.43Å; G200-K355 WeakPolarHBondContact CA-O 3.38Å; G200-K355 PolarHBondContact N-O 3.44Å
201G93.6Very high94.1Very high0 Ų034.9 Ų34.90%018%0.179CC..G310 helixtrans-60.9-12.7166.800000113.6D197 G198 N199 Y203 E204 A205D197-G201 WeakPolarHBondContact OD1-CA 3.26Å; D197-G201 WeakPolarHBondContact OD2-CA 3.47Å; G198-G201 PolarHBondContact O-N 2.64Å; N199-G201 VanDerWaalsContact C-N 3.29Å; G201-Y203 VanDerWaalsContact C-N 3.33Å; G201-Y203 PolarHBondContact O-N 3.17Å; G201-E204 PolarHBondContact O-N 2.99Å; G201-A205 WeakPolarHBondContact O-CB 3.3Å; G201-A205 PolarHBondContact O-N 2.85Å
202L96.4Very high94.4Very high0 Ų030.8 Ų30.80%016%0.16CC..Hα-helixtrans-45-51175.2174.165.2000113.6I81 L83 M141 F170 N199 G200 E204 A205 L206 V225 I357I81-L202 HydrophobicContact CD1-CD1 4.3Å; I81-L202 HydrophobicContact CG2-CD1 3.81Å; L83-L202 HydrophobicContact CD2-CD1 4.22Å; L83-L202 HydrophobicContact CD2-CD2 4.21Å; M141-L202 HydrophobicContact CE-CB 4.41Å; M141-L202 VanDerWaalsContact SD-CA 3.54Å; M141-L202 HydrophobicContact SD-CB 3.87Å; M141-L202 HydrophobicContact SD-CD1 3.72Å; M141-L202 HydrophobicContact SD-CG 4.44Å; F170-L202 HydrophobicContact CE2-CD1 3.98Å; F170-L202 HydrophobicContact CZ-CD1 3.75Å; N199-L202 VanDerWaalsContact O-CB 3.31Å; N199-L202 WeakPolarHBondContact O-CB 3.31Å; N199-L202 PolarHBondContact O-N 3.31Å; G200-L202 PolarHBondContact O-N 3.25Å; G200-L202 VanDerWaalsContact O-N 3.11Å; L202-E204 PolarHBondContact O-N 3.16Å; L202-A205 PolarHBondContact O-N 3.34Å; L202-L206 HydrophobicContact CD1-CD1 3.79Å; L202-L206 HydrophobicContact CD1-CD2 4.24Å; L202-L206 HydrophobicContact CD1-CG 3.75Å; L202-L206 HydrophobicContact CD2-CD1 4.44Å; L202-L206 HydrophobicContact CG-CD1 3.81Å; L202-L206 HydrophobicContact CG-CG 4.17Å; L202-L206 WeakPolarHBondContact O-CB 2.83Å; L202-L206 VanDerWaalsContact O-CG 3.23Å; L202-L206 WeakPolarHBondContact O-CG 3.36Å; L202-L206 PolarHBondContact O-N 2.85Å; L202-V225 HydrophobicContact CD2-CG1 3.87Å; L202-V225 HydrophobicContact CD2-CG2 4.49Å; L202-I357 HydrophobicContact CD2-CD1 3.78Å; L202-I357 HydrophobicContact CD2-CG1 4.26Å
203Y96.3Very high94.6Very high10 Ų1032 Ų324%0.03917%0.167CC..Hα-helixtrans-68-39.4-169.7-53.2-73.9000112.1G200 G201 K207 F309 L314 V317 A318 L324 I357 V360G200-Y203 WeakPolarHBondContact O-CD2 3.43Å; G201-Y203 VanDerWaalsContact C-N 3.33Å; G201-Y203 PolarHBondContact O-N 3.17Å; Y203-K207 PolarHBondContact O-N 2.87Å; Y203-F309 VanDerWaalsContact OH-CZ 3.3Å; Y203-F309 WeakPolarHBondContact OH-CZ 3.41Å; Y203-L314 HydrophobicContact CD1-CD2 4.02Å; Y203-L314 HydrophobicContact CE1-CD2 3.74Å; Y203-V317 HydrophobicContact CD1-CG2 3.55Å; Y203-V317 HydrophobicContact CE1-CG2 3.98Å; Y203-V317 HydrophobicContact CG-CG2 4.2Å; Y203-A318 WeakPolarHBondContact O-CB 3.32Å; Y203-L324 HydrophobicContact CD2-CD1 3.53Å; Y203-L324 HydrophobicContact CE2-CD1 3.76Å; Y203-I357 HydrophobicContact CE2-CG1 4.46Å; Y203-I357 WeakPolarHBondContact OH-CG1 3.41Å; Y203-I357 PolarHBondContact OH-O 2.77Å; Y203-V360 HydrophobicContact CD1-CG1 4.21Å; Y203-V360 HydrophobicContact CD2-CG1 3.69Å; Y203-V360 HydrophobicContact CE1-CG1 3.81Å; Y203-V360 HydrophobicContact CE1-CG2 4.23Å; Y203-V360 HydrophobicContact CE2-CB 4.33Å; Y203-V360 HydrophobicContact CE2-CG1 3.22Å; Y203-V360 HydrophobicContact CE2-CG2 4.28Å; Y203-V360 HydrophobicContact CG-CG1 4.16Å; Y203-V360 WeakPolarHBondContact OH-CG2 3.35Å
204E94.1Very high94.9Very high79 Ų7934.6 Ų34.637%0.36918%0.182SC..Hα-helixtrans-64.9-47173.6-173.7-174.2136.500110.6S173 G201 L202 L206 K207 K208 K355S173-E204 PolarHBondContact OG-OE1 3.03Å; G201-E204 PolarHBondContact O-N 2.99Å; L202-E204 PolarHBondContact O-N 3.16Å; E204-L206 PolarHBondContact O-N 3.48Å; E204-K207 PolarHBondContact O-N 3.08Å; E204-K208 VanDerWaalsContact O-CB 3.31Å; E204-K208 WeakPolarHBondContact O-CB 3.48Å; E204-K208 PolarHBondContact O-N 2.76Å; E204-K355 IonicContact OE2-NZ 3.21Å; E204-K355 PolarHBondContact OE2-NZ 3.02Å
205A95.4Very high95.2Very high0 Ų032.3 Ų32.30%017%0.169CC..Hα-helixtrans-61.2-42.2179.200000112.2F170 G201 L202 K207 K208 E209F170-A205 HydrophobicContact CD2-CB 3.91Å; F170-A205 HydrophobicContact CE2-CB 3.95Å; G201-A205 WeakPolarHBondContact O-CB 3.3Å; G201-A205 PolarHBondContact O-N 2.85Å; L202-A205 PolarHBondContact O-N 3.34Å; A205-K207 VanDerWaalsContact C-N 3.3Å; A205-K207 PolarHBondContact O-N 2.86Å; A205-K208 PolarHBondContact O-N 2.9Å; A205-E209 VanDerWaalsContact O-CB 3.23Å; A205-E209 WeakPolarHBondContact O-CB 3.4Å; A205-E209 VanDerWaalsContact O-CG 3.31Å; A205-E209 WeakPolarHBondContact O-CG 3.46Å; A205-E209 PolarHBondContact O-N 2.84Å
206L97.1Very high95.6Very high1 Ų134.9 Ų34.91%0.00519%0.186CC..Hα-helixtrans-59.5-37.8177.4-77.4176.6000113I81 F170 L202 E204 V211 L212 L314I81-L206 HydrophobicContact CD1-CD1 3.96Å; I81-L206 HydrophobicContact CD1-CD2 3.85Å; I81-L206 HydrophobicContact CD1-CG 4.47Å; F170-L206 HydrophobicContact CE2-CD2 3.98Å; F170-L206 HydrophobicContact CE2-CG 4.28Å; F170-L206 HydrophobicContact CZ-CD2 3.87Å; F170-L206 HydrophobicContact CZ-CG 4.48Å; L202-L206 HydrophobicContact CD1-CD1 3.79Å; L202-L206 HydrophobicContact CD1-CD2 4.24Å; L202-L206 HydrophobicContact CD1-CG 3.75Å; L202-L206 HydrophobicContact CD2-CD1 4.44Å; L202-L206 HydrophobicContact CG-CD1 3.81Å; L202-L206 HydrophobicContact CG-CG 4.17Å; L202-L206 WeakPolarHBondContact O-CB 2.83Å; L202-L206 VanDerWaalsContact O-CG 3.23Å; L202-L206 WeakPolarHBondContact O-CG 3.36Å; L202-L206 PolarHBondContact O-N 2.85Å; E204-L206 PolarHBondContact O-N 3.48Å; L206-V211 HydrophobicContact CD2-CB 3.7Å; L206-V211 HydrophobicContact CD2-CG1 3.54Å; L206-V211 HydrophobicContact CD2-CG2 4.34Å; L206-V211 PolarHBondContact O-N 3.5Å; L206-V211 VanDerWaalsContact O-N 3.11Å; L206-L212 HydrophobicContact CB-CD1 4.32Å; L206-L212 HydrophobicContact CB-CD2 4.08Å; L206-L212 HydrophobicContact CB-CG 3.92Å; L206-L212 HydrophobicContact CD1-CD2 4.18Å; L206-L212 PolarHBondContact O-N 3.33Å; L206-L314 HydrophobicContact CD1-CD1 4.31Å; L206-L314 HydrophobicContact CD1-CD2 4.35Å
207K94.8Very high95.9Very high84 Ų8437.9 Ų37.937%0.36521%0.214SC..Hα-helixtrans-75.3-51.2175.9171.6174.1170.1-176.60111Y203 E204 A205 E209 G210 A318 D321Y203-K207 PolarHBondContact O-N 2.87Å; E204-K207 PolarHBondContact O-N 3.08Å; A205-K207 VanDerWaalsContact C-N 3.3Å; A205-K207 PolarHBondContact O-N 2.86Å; K207-E209 PolarHBondContact O-N 3.32Å; K207-G210 PolarHBondContact O-N 3.27Å; K207-A318 HydrophobicContact CB-CB 4.17Å; K207-A318 WeakPolarHBondContact CD-O 3.48Å; K207-D321 IonicContact NZ-OD1 3.77Å; K207-D321 PolarHBondContact NZ-OD1 2.87Å; K207-D321 IonicContact NZ-OD2 2.92Å; K207-D321 PolarHBondContact NZ-OD2 3.18Å
208K94.4Very high96.2Very high138 Ų13842.4 Ų42.460%0.623%0.233SC*.Hα-helixtrans-61.6-42.4-175.5-179.1-175.9171.8-172.10112.6E204 A205 G210E204-K208 VanDerWaalsContact O-CB 3.31Å; E204-K208 WeakPolarHBondContact O-CB 3.48Å; E204-K208 PolarHBondContact O-N 2.76Å; A205-K208 PolarHBondContact O-N 2.9Å; K208-G210 VanDerWaalsContact C-N 3.28Å; K208-G210 PolarHBondContact O-N 2.94Å
209E96.1Very high96.5Very high90 Ų9044 Ų4442%0.42125%0.249SC..THydrogen-bonded Turntrans-88.68.2-176.1-57.7-70.6118.600112.4F170 A205 K207 V211F170-E209 HydrophobicContact CB-CB 3.91Å; F170-E209 HydrophobicContact CB-CG 4.06Å; A205-E209 VanDerWaalsContact O-CB 3.23Å; A205-E209 WeakPolarHBondContact O-CB 3.4Å; A205-E209 VanDerWaalsContact O-CG 3.31Å; A205-E209 WeakPolarHBondContact O-CG 3.46Å; A205-E209 PolarHBondContact O-N 2.84Å; K207-E209 PolarHBondContact O-N 3.32Å; E209-V211 HydrophobicContact CB-CG2 4.09Å; E209-V211 PolarHBondContact O-N 3.44Å; E209-V211 VanDerWaalsContact O-N 3.14Å
210G96.7Very high96.7Very high23 Ų2342.2 Ų42.224%0.23724%0.24CC..THydrogen-bonded Turntrans6810.6176.700000115.2K207 K208 L212 D213 V214K207-G210 PolarHBondContact O-N 3.27Å; K208-G210 VanDerWaalsContact C-N 3.28Å; K208-G210 PolarHBondContact O-N 2.94Å; G210-L212 VanDerWaalsContact C-N 3.3Å; G210-L212 PolarHBondContact O-N 2.8Å; G210-D213 PolarHBondContact O-N 3.45Å; G210-D213 VanDerWaalsContact O-N 3.14Å; G210-V214 PolarHBondContact O-N 3.42Å
211V98.1Very high96.9Very high2 Ų248.9 Ų48.91%0.01226%0.264CS..Hα-helixtrans-61.7-39.2-175.7-178.80000111.2C139 I168 F170 L206 E209 D213 V214 L215C139-V211 HydrophobicContact CB-CG1 4.43Å; I168-V211 HydrophobicContact CG2-CG2 4.23Å; F170-V211 HydrophobicContact CB-CG2 3.76Å; F170-V211 HydrophobicContact CD1-CG2 4.06Å; F170-V211 HydrophobicContact CD2-CG2 4.17Å; F170-V211 HydrophobicContact CG-CG2 3.74Å; L206-V211 HydrophobicContact CD2-CB 3.7Å; L206-V211 HydrophobicContact CD2-CG1 3.54Å; L206-V211 HydrophobicContact CD2-CG2 4.34Å; L206-V211 PolarHBondContact O-N 3.5Å; L206-V211 VanDerWaalsContact O-N 3.11Å; E209-V211 HydrophobicContact CB-CG2 4.09Å; E209-V211 PolarHBondContact O-N 3.44Å; E209-V211 VanDerWaalsContact O-N 3.14Å; V211-D213 VanDerWaalsContact C-N 3.26Å; V211-D213 PolarHBondContact O-N 3.17Å; V211-V214 PolarHBondContact O-N 3.43Å; V211-L215 HydrophobicContact CG1-CD1 4.15Å; V211-L215 HydrophobicContact CG1-CG 4.22Å; V211-L215 VanDerWaalsContact O-CG 3.32Å; V211-L215 WeakPolarHBondContact O-CG 3.36Å; V211-L215 PolarHBondContact O-N 3.05Å
212L97.8Very high97.1Very high3 Ų350.4 Ų50.42%0.01627%0.27CS..Hα-helixtrans-60.9-35.4178.1-64.1176.3000112.8L206 G210 S216 L311 L314 Q315 A318L206-L212 HydrophobicContact CB-CD1 4.32Å; L206-L212 HydrophobicContact CB-CD2 4.08Å; L206-L212 HydrophobicContact CB-CG 3.92Å; L206-L212 HydrophobicContact CD1-CD2 4.18Å; L206-L212 PolarHBondContact O-N 3.33Å; G210-L212 VanDerWaalsContact C-N 3.3Å; G210-L212 PolarHBondContact O-N 2.8Å; L212-S216 WeakPolarHBondContact O-CB 3.49Å; L212-S216 PolarHBondContact O-N 3.27Å; L212-L311 HydrophobicContact CD2-CD1 4.02Å; L212-L314 HydrophobicContact CD2-CB 3.88Å; L212-Q315 HydrophobicContact CB-CG 4.45Å; L212-Q315 HydrophobicContact CD1-CG 4.37Å; L212-A318 HydrophobicContact CD1-CB 3.69Å
213D97.9Very high97.2Very high94 Ų9450.4 Ų50.450%0.50327%0.27SS..Hα-helixtrans-74.5-38.3179.8-63-30.5000110.5G210 V211 S216 A217 K319G210-D213 PolarHBondContact O-N 3.45Å; G210-D213 VanDerWaalsContact O-N 3.14Å; V211-D213 VanDerWaalsContact C-N 3.26Å; V211-D213 PolarHBondContact O-N 3.17Å; D213-S216 PolarHBondContact O-N 2.9Å; D213-A217 WeakPolarHBondContact O-CB 3.21Å; D213-A217 PolarHBondContact O-N 2.9Å; D213-K319 IonicContact OD1-NZ 3.84Å
214V98.1Very high97.4Very high60 Ų6049.9 Ų49.936%0.36427%0.268SS..Hα-helixtrans-62.2-45.3172.6179.10000111.4I168 G210 V211 S216 A217 K218I168-V214 HydrophobicContact CD1-CB 4.29Å; I168-V214 HydrophobicContact CD1-CG1 3.51Å; G210-V214 PolarHBondContact O-N 3.42Å; V211-V214 PolarHBondContact O-N 3.43Å; V214-S216 VanDerWaalsContact C-N 3.32Å; V214-S216 PolarHBondContact O-N 2.84Å; V214-A217 PolarHBondContact O-N 3Å; V214-K218 HydrophobicContact CG1-CD 4.18Å; V214-K218 WeakPolarHBondContact O-CG 3.48Å; V214-K218 PolarHBondContact O-N 3.26Å; V214-K218 VanDerWaalsContact O-N 3.07Å
215L98.5Very high97.6Very high0 Ų046.1 Ų46.10%025%0.251CS..Hα-helixtrans-62.4-40.8176.1-67.1179.2000111.5A79 T137 V211 K218 G219 I220 V223 L311A79-L215 HydrophobicContact CB-CD2 3.68Å; T137-L215 HydrophobicContact CG2-CD2 3.98Å; V211-L215 HydrophobicContact CG1-CD1 4.15Å; V211-L215 HydrophobicContact CG1-CG 4.22Å; V211-L215 VanDerWaalsContact O-CG 3.32Å; V211-L215 WeakPolarHBondContact O-CG 3.36Å; V211-L215 PolarHBondContact O-N 3.05Å; L215-K218 PolarHBondContact O-N 2.72Å; L215-G219 PolarHBondContact O-N 3.12Å; L215-I220 HydrophobicContact CB-CB 4.12Å; L215-I220 HydrophobicContact CB-CG1 4.24Å; L215-I220 HydrophobicContact CD2-CB 4.45Å; L215-I220 HydrophobicContact CD2-CG1 3.93Å; L215-I220 HydrophobicContact CD2-CG2 4.46Å; L215-I220 VanDerWaalsContact O-CB 3.32Å; L215-I220 WeakPolarHBondContact O-CB 3.18Å; L215-I220 WeakPolarHBondContact O-CG1 3.46Å; L215-I220 PolarHBondContact O-N 3Å; L215-V223 HydrophobicContact CD1-CG2 4.21Å; L215-L311 HydrophobicContact CB-CD1 3.96Å; L215-L311 HydrophobicContact CB-CD2 4.28Å; L215-L311 HydrophobicContact CD1-CD1 4.24Å
216S98.2Very high97.7Very high60 Ų6046.2 Ų46.242%0.4225%0.251SS..Hα-helixtrans-63-46176.1-168.30000111.8L212 D213 V214 K218 G219L212-S216 WeakPolarHBondContact O-CB 3.49Å; L212-S216 PolarHBondContact O-N 3.27Å; D213-S216 PolarHBondContact O-N 2.9Å; V214-S216 VanDerWaalsContact C-N 3.32Å; V214-S216 PolarHBondContact O-N 2.84Å; S216-K218 PolarHBondContact O-N 3.32Å; S216-G219 PolarHBondContact O-N 3.11Å
217A98.1Very high97.7Very high93 Ų9347.3 Ų47.377%0.76926%0.258SS*.Hα-helixtrans-63.5-29.4178.500000112.8D213 V214 G219D213-A217 WeakPolarHBondContact O-CB 3.21Å; D213-A217 PolarHBondContact O-N 2.9Å; V214-A217 PolarHBondContact O-N 3Å; A217-G219 VanDerWaalsContact C-N 3.29Å
218K97.7Very high97.7Very high97 Ų9743.7 Ų43.742%0.42224%0.243SC..THydrogen-bonded Turntrans-80.4-3.3174.5-72.7175.8177.3-74.80114T137 V214 L215 S216 I220T137-K218 HydrophobicContact CG2-CD 4.27Å; T137-K218 WeakPolarHBondContact OG1-CD 3.36Å; V214-K218 HydrophobicContact CG1-CD 4.18Å; V214-K218 WeakPolarHBondContact O-CG 3.48Å; V214-K218 PolarHBondContact O-N 3.26Å; V214-K218 VanDerWaalsContact O-N 3.07Å; L215-K218 PolarHBondContact O-N 2.72Å; S216-K218 PolarHBondContact O-N 3.32Å; K218-I220 VanDerWaalsContact C-N 3.33Å; K218-I220 HydrophobicContact CB-CD1 4.46Å; K218-I220 HydrophobicContact CB-CG1 4.01Å
219G98.1Very high97.8Very high41 Ų4137.9 Ų37.942%0.42322%0.219SC..THydrogen-bonded Turntrans7519.3-17900000114.6L215 S216 A217L215-G219 PolarHBondContact O-N 3.12Å; S216-G219 PolarHBondContact O-N 3.11Å; A217-G219 VanDerWaalsContact C-N 3.29Å
220I98.7Very high97.8Very high9 Ų933.9 Ų33.95%0.04620%0.2CC..  trans-65139.1179.4-58.6-60000110.3G76 A79 L215 K218 V223 L311G76-I220 WeakPolarHBondContact O-CD1 3.13Å; A79-I220 HydrophobicContact CB-CD1 4.04Å; A79-I220 HydrophobicContact CB-CG1 4.14Å; A79-I220 HydrophobicContact CB-CG2 3.72Å; L215-I220 HydrophobicContact CB-CB 4.12Å; L215-I220 HydrophobicContact CB-CG1 4.24Å; L215-I220 HydrophobicContact CD2-CB 4.45Å; L215-I220 HydrophobicContact CD2-CG1 3.93Å; L215-I220 HydrophobicContact CD2-CG2 4.46Å; L215-I220 VanDerWaalsContact O-CB 3.32Å; L215-I220 WeakPolarHBondContact O-CB 3.18Å; L215-I220 WeakPolarHBondContact O-CG1 3.46Å; L215-I220 PolarHBondContact O-N 3Å; K218-I220 VanDerWaalsContact C-N 3.33Å; K218-I220 HydrophobicContact CB-CD1 4.46Å; K218-I220 HydrophobicContact CB-CG1 4.01Å; I220-V223 HydrophobicContact CG2-CG2 3.87Å; I220-L311 WeakPolarHBondContact O-CD2 3.29Å
221R98.5Very high97.9Very high142 Ų14232.9 Ų32.954%0.53619%0.189SC..  trans-120.5-36.5176.5-62.8-171175.7-162-2.3113Q77 T310 L311Q77-R221 HydrophobicContact CB-CB 4.24Å; Q77-R221 HydrophobicContact CB-CG 4.27Å; Q77-R221 HydrophobicContact CG-CG 4.38Å; Q77-R221 PolarHBondContact O-N 2.74Å; R221-T310 CarbonylContact O-C 3.55Å; R221-T310 VanDerWaalsContact O-CA 3.3Å; R221-T310 WeakPolarHBondContact O-CA 3.2Å; R221-L311 PolarHBondContact O-N 2.78Å
222Y98.8Very high97.9Very high32 Ų3232.9 Ų32.913%0.12519%0.189CC..EExtended strand (participates in β ladder)trans-119.7128.8-175.4-51-72.7000109.8A72 Q77 V78 A79 I241 R245 L308 T310A72-Y222 HydrophobicContact CB-CD2 4.04Å; A72-Y222 HydrophobicContact CB-CE2 4.11Å; Q77-Y222 HydrophobicContact CB-CD2 4.48Å; Q77-Y222 PolarHBondContact O-N 3.36Å; V78-Y222 WeakPolarHBondContact CA-O 3.4Å; A79-Y222 PolarHBondContact N-O 3.46Å; Y222-I241 HydrophobicContact CD2-CG2 4.17Å; Y222-I241 HydrophobicContact CG-CG2 4.23Å; Y222-R245 HydrophobicContact CE1-CG 3.77Å; Y222-R245 HydrophobicContact CE2-CG 3.89Å; Y222-R245 VanDerWaalsContact CZ-CG 3.42Å; Y222-R245 WeakPolarHBondContact OH-CG 3.29Å; Y222-L308 HydrophobicContact CD1-CD2 4.2Å; Y222-T310 HydrophobicContact CD1-CG2 4.45Å; Y222-T310 HydrophobicContact CE1-CG2 4.45Å
223V98.9Very high97.9Very high0 Ų032.8 Ų32.80%019%0.189CC..EExtended strand (participates in β ladder)trans-123.3108.8-177.2-173.90000108.5A79 I81 L215 I220 V225 L308 F309 L314A79-V223 WeakPolarHBondContact O-CA 3.46Å; I81-V223 HydrophobicContact CD1-CG1 3.38Å; I81-V223 HydrophobicContact CG1-CG1 3.58Å; L215-V223 HydrophobicContact CD1-CG2 4.21Å; I220-V223 HydrophobicContact CG2-CG2 3.87Å; V223-V225 HydrophobicContact CG1-CG2 4.11Å; V223-L308 WeakPolarHBondContact O-CA 3.47Å; V223-F309 PolarHBondContact N-O 2.86Å; V223-F309 PolarHBondContact O-N 2.87Å; V223-L314 HydrophobicContact CB-CD1 3.8Å; V223-L314 HydrophobicContact CG1-CD1 3.93Å; V223-L314 HydrophobicContact CG2-CD1 3.85Å
224H98.8Very high97.9Very high0 Ų029.2 Ų29.20%017%0.168CC..EExtended strand (participates in β ladder)trans-89.1115.8176.4171.2-169000109.5A79 V80 I81 R234 A236 N306 H307A79-H224 PolarHBondContact O-N 3.36Å; V80-H224 CarbonylContact C-O 3.5Å; V80-H224 WeakPolarHBondContact CA-O 3.41Å; V80-H224 HydrophobicContact CG1-CB 4.22Å; I81-H224 PolarHBondContact N-O 3.26Å; H224-R234 PolarHBondContact CE1-O 3.11Å; H224-A236 WeakPolarHBondContact ND1-CA 3.4Å; H224-A236 PolarHBondContact ND1-N 3.04Å; H224-N306 PolarHBondContact CD2-OD1 3.41Å; H224-N306 PolarHBondContact NE2-ND2 3.45Å; H224-N306 PolarHBondContact NE2-OD1 2.76Å; H224-H307 CarbonylContact C-O 3.59Å; H224-H307 VanDerWaalsContact CA-O 3.31Å; H224-H307 WeakPolarHBondContact CA-O 3.24Å; H224-H307 PolarHBondContact CD2-O 2.85Å
225V98.8Very high97.9Very high0 Ų026.4 Ų26.40%015%0.151CC..EExtended strand (participates in β ladder)trans-107.7128.7-177.5-168.80000110.9I81 L83 L202 V223 H307 F309 I357I81-V225 HydrophobicContact CB-CB 4.35Å; I81-V225 HydrophobicContact CB-CG1 4Å; I81-V225 HydrophobicContact CB-CG2 4Å; I81-V225 HydrophobicContact CD1-CG2 4.01Å; I81-V225 HydrophobicContact CG1-CG2 4.37Å; I81-V225 HydrophobicContact CG2-CG1 4.11Å; I81-V225 WeakPolarHBondContact O-CA 3.48Å; L83-V225 HydrophobicContact CD1-CG1 4.04Å; L83-V225 HydrophobicContact CD2-CG1 3.8Å; L83-V225 HydrophobicContact CG-CG1 3.94Å; L202-V225 HydrophobicContact CD2-CG1 3.87Å; L202-V225 HydrophobicContact CD2-CG2 4.49Å; V223-V225 HydrophobicContact CG1-CG2 4.11Å; V225-H307 HydrophobicContact CB-CB 4.49Å; V225-H307 PolarHBondContact N-O 3.28Å; V225-H307 PolarHBondContact O-N 2.87Å; V225-F309 HydrophobicContact CB-CD2 4.36Å; V225-F309 HydrophobicContact CB-CE2 4.09Å; V225-F309 HydrophobicContact CG2-CD2 3.52Å; V225-F309 HydrophobicContact CG2-CE2 3.69Å; V225-I357 HydrophobicContact CB-CD1 4.22Å; V225-I357 HydrophobicContact CG1-CD1 3.48Å; V225-I357 VanDerWaalsContact CG1-CD1 3.48Å
226Y98.5Very high97.9Very high2 Ų226.4 Ų26.41%0.00815%0.151CC..EExtended strand (participates in β ladder)trans-149.4159.9-174.970.1-77.8000113V80 I81 L82 L83 Q114 W138 V233 V235V80-Y226 HydrophobicContact CB-CE1 4.12Å; I81-Y226 WeakPolarHBondContact O-CD1 3.48Å; I81-Y226 PolarHBondContact O-N 2.83Å; L82-Y226 HydrophobicContact CB-CE1 4.34Å; L82-Y226 HydrophobicContact CD1-CD2 4.04Å; L82-Y226 HydrophobicContact CD1-CE1 4.48Å; L82-Y226 HydrophobicContact CD1-CE2 3.53Å; L83-Y226 WeakPolarHBondContact CG-O 3.31Å; L83-Y226 PolarHBondContact N-O 3.26Å; Q114-Y226 HydrophobicContact CG-CE2 4.38Å; Q114-Y226 VanDerWaalsContact OE1-CE2 3.22Å; Q114-Y226 PolarHBondContact OE1-OH 3.11Å; W138-Y226 WeakPolarHBondContact CZ2-OH 3.23Å; W138-Y226 PolarHBondContact NE1-OH 2.71Å; Y226-V233 HydrophobicContact CD2-CB 4.33Å; Y226-V233 HydrophobicContact CD2-CG1 4.07Å; Y226-V233 HydrophobicContact CD2-CG2 3.61Å; Y226-V233 HydrophobicContact CE2-CG1 3.99Å; Y226-V233 HydrophobicContact CE2-CG2 4.22Å; Y226-V233 HydrophobicContact CG-CG2 4Å; Y226-V235 HydrophobicContact CE1-CG1 3.81Å; Y226-V235 HydrophobicContact CE1-CG2 4.38Å; Y226-V235 HydrophobicContact CE2-CG2 3.94Å
227C96.1Very high97.9Very high23 Ų2323.7 Ų23.716%0.15513%0.132CC..EExtended strand (participates in β ladder)trans-85.3143.1176.4-67.50000112.1D229C227-D229 WeakPolarHBondContact CB-OD1 3.38Å; C227-D229 PolarHBondContact O-N 3.19Å; C227-D229 VanDerWaalsContact O-N 3.13Å
228V95.8Very high97.8Very high8 Ų819.7 Ų19.75%0.04810%0.098CC..THydrogen-bonded Turntrans-62.9-20.9-179.769.90000114.1L82 L83 K97 F111 Q114 N230L82-V228 VanDerWaalsContact CD1-CA 3.45Å; L82-V228 HydrophobicContact CD1-CB 3.57Å; L82-V228 HydrophobicContact CD1-CG2 4.09Å; L82-V228 HydrophobicContact CD2-CG2 4.27Å; L82-V228 HydrophobicContact CG-CB 4.32Å; L83-V228 PolarHBondContact O-N 3.38Å; K97-V228 HydrophobicContact CB-CG1 4.18Å; K97-V228 HydrophobicContact CD-CG1 4.4Å; F111-V228 HydrophobicContact CD1-CG2 4.23Å; F111-V228 HydrophobicContact CE1-CG2 3.9Å; Q114-V228 PolarHBondContact NE2-O 3.32Å; V228-N230 PolarHBondContact O-N 3.14Å
229D95.1Very high97.7Very high17 Ų1715.3 Ų15.39%0.0918%0.079CC..THydrogen-bonded Turntrans-90.18.9-167.357.612.3000116.2K97 C227 P380 L381 K382K97-D229 HydrophobicContact CD-CB 3.48Å; K97-D229 VanDerWaalsContact CD-CB 3.48Å; K97-D229 IonicContact NZ-OD2 3.26Å; K97-D229 PolarHBondContact NZ-OD2 2.98Å; C227-D229 WeakPolarHBondContact CB-OD1 3.38Å; C227-D229 PolarHBondContact O-N 3.19Å; C227-D229 VanDerWaalsContact O-N 3.13Å; D229-P380 CarbonylContact O-C 3.54Å; D229-P380 VanDerWaalsContact O-CA 3.29Å; D229-P380 WeakPolarHBondContact O-CA 3.36Å; D229-L381 HydrophobicContact CB-CB 4.46Å; D229-L381 WeakPolarHBondContact CB-O 3.42Å; D229-L381 PolarHBondContact O-N 3.45Å; D229-K382 IonicContact OD1-NZ 3.74Å; D229-K382 PolarHBondContact OD1-NZ 3.48Å; D229-K382 WeakPolarHBondContact OD2-CD 3.17Å; D229-K382 WeakPolarHBondContact OD2-CE 3.35Å; D229-K382 IonicContact OD2-NZ 2.77Å; D229-K382 PolarHBondContact OD2-NZ 2.74Å
230N97.3Very high97.7Very high5 Ų513.3 Ų13.33%0.0276%0.059CC..BIsolated β-bridgetrans-101.4109.3174.5178.211.7000110.4V228 L232 V233 E377 S379V228-N230 PolarHBondContact O-N 3.14Å; N230-L232 PolarHBondContact O-N 3.11Å; N230-L232 PolarHBondContact OD1-N 3.33Å; N230-L232 VanDerWaalsContact OD1-N 3.12Å; N230-V233 HydrophobicContact CB-CB 4.15Å; N230-V233 WeakPolarHBondContact O-CB 3.31Å; N230-V233 WeakPolarHBondContact O-CG1 3.23Å; N230-V233 PolarHBondContact O-N 2.99Å; N230-E377 PolarHBondContact ND2-O 3.14Å; N230-S379 PolarHBondContact OD1-N 2.66Å; N230-S379 PolarHBondContact OD1-O 3.49Å
231I98Very high97.7Very high2 Ų212.9 Ų12.91%0.016%0.057CC..THydrogen-bonded Turntrans-67.4-26.9-178-164.2168.8000112.4V102 L110 L113 R117 V233 S379 C395 L399V102-I231 HydrophobicContact CG1-CD1 4.36Å; V102-I231 HydrophobicContact CG2-CD1 3.5Å; V102-I231 VanDerWaalsContact CG2-CD1 3.5Å; L110-I231 HydrophobicContact CD2-CB 4.24Å; L110-I231 HydrophobicContact CD2-CD1 4.46Å; L110-I231 HydrophobicContact CD2-CG1 4.09Å; L113-I231 HydrophobicContact CD1-CD1 4.28Å; L113-I231 HydrophobicContact CD1-CG1 4.01Å; R117-I231 PolarHBondContact NH1-O 3.04Å; R117-I231 PolarHBondContact NH2-O 3.05Å; I231-V233 VanDerWaalsContact C-N 3.33Å; I231-S379 PolarHBondContact N-O 3.01Å; I231-S379 VanDerWaalsContact N-O 3.15Å; I231-C395 HydrophobicContact CB-CB 4.44Å; I231-C395 HydrophobicContact CD1-CB 4.28Å; I231-C395 HydrophobicContact CG2-CB 3.88Å; I231-L399 HydrophobicContact CD1-CB 4.42Å; I231-L399 HydrophobicContact CD1-CD2 4.05Å; I231-L399 HydrophobicContact CG1-CD1 4.49Å; I231-L399 HydrophobicContact CG1-CD2 4.41Å
232L98.4Very high97.6Very high3 Ų36.1 Ų6.12%0.0163%0.031CC..THydrogen-bonded Turntrans-89.97-179.6-56.2-174.3000113.2N230 R234 D398 L399 L402N230-L232 PolarHBondContact O-N 3.11Å; N230-L232 PolarHBondContact OD1-N 3.33Å; N230-L232 VanDerWaalsContact OD1-N 3.12Å; L232-R234 PolarHBondContact O-N 3.34Å; L232-D398 HydrophobicContact CD1-CB 4.3Å; L232-L399 HydrophobicContact CD2-CB 4.2Å; L232-L399 HydrophobicContact CD2-CD1 3.68Å; L232-L402 HydrophobicContact CD2-CD2 3.89Å
233V98.3Very high97.5Very high1 Ų14.7 Ų4.71%0.0063%0.025CC..  trans-60.1122.6-175.765.40000112.7Q114 R117 Y226 N230 I231 V235Q114-V233 HydrophobicContact CG-CG1 4.09Å; R117-V233 WeakPolarHBondContact CD-O 3.49Å; R117-V233 PolarHBondContact NH1-O 3.1Å; Y226-V233 HydrophobicContact CD2-CB 4.33Å; Y226-V233 HydrophobicContact CD2-CG1 4.07Å; Y226-V233 HydrophobicContact CD2-CG2 3.61Å; Y226-V233 HydrophobicContact CE2-CG1 3.99Å; Y226-V233 HydrophobicContact CE2-CG2 4.22Å; Y226-V233 HydrophobicContact CG-CG2 4Å; N230-V233 HydrophobicContact CB-CB 4.15Å; N230-V233 WeakPolarHBondContact O-CB 3.31Å; N230-V233 WeakPolarHBondContact O-CG1 3.23Å; N230-V233 PolarHBondContact O-N 2.99Å; I231-V233 VanDerWaalsContact C-N 3.33Å; V233-V235 VanDerWaalsContact C-N 3.33Å; V233-V235 HydrophobicContact CG1-CG2 3.79Å; V233-V235 HydrophobicContact CG2-CG2 4.37Å; V233-V235 PolarHBondContact O-N 2.97Å
234R97.3Very high97.3Very high19 Ų194.7 Ų4.77%0.0723%0.025CC..  trans-79.479.2168.9-66.3-169.5-175.8-171.24.9110.2R54 H224 L232 A236 D237 E376 E377 Y432R54-R234 VanDerWaalsContact CZ-NH1 3.3Å; R54-R234 VanDerWaalsContact NH2-NH1 3.14Å; H224-R234 PolarHBondContact CE1-O 3.11Å; L232-R234 PolarHBondContact O-N 3.34Å; R234-A236 PolarHBondContact O-N 2.63Å; R234-D237 HydrophobicContact CB-CB 3.87Å; R234-D237 WeakPolarHBondContact O-CB 3.34Å; R234-D237 PolarHBondContact O-N 3.22Å; R234-D237 VanDerWaalsContact O-N 3.08Å; R234-E376 IonicContact CZ-OE2 4Å; R234-E376 IonicContact NH2-OE2 3.53Å; R234-E376 PolarHBondContact NH2-OE2 3.38Å; R234-E377 HydrophobicContact CG-CG 4.31Å; R234-Y432 WeakPolarHBondContact CB-OH 3.4Å; R234-Y432 PolarHBondContact O-OH 3.04Å
235V98Very high97.1Very high0 Ų07.8 Ų7.80%04%0.037CC..THydrogen-bonded Turntrans-56.8132.3-179.2-173.50000109.8V80 Q114 L118 L121 Y226 V233 D237 Y432V80-V235 HydrophobicContact CB-CG1 4.3Å; V80-V235 HydrophobicContact CG1-CG1 3.94Å; V80-V235 HydrophobicContact CG2-CG1 4.14Å; Q114-V235 HydrophobicContact CB-CG2 3.99Å; Q114-V235 HydrophobicContact CG-CG2 3.89Å; L118-V235 HydrophobicContact CD1-CG1 4.36Å; L118-V235 HydrophobicContact CD2-CG1 3.66Å; L118-V235 HydrophobicContact CG-CG1 3.92Å; L121-V235 WeakPolarHBondContact CD1-O 3.17Å; Y226-V235 HydrophobicContact CE1-CG1 3.81Å; Y226-V235 HydrophobicContact CE1-CG2 4.38Å; Y226-V235 HydrophobicContact CE2-CG2 3.94Å; V233-V235 VanDerWaalsContact C-N 3.33Å; V233-V235 HydrophobicContact CG1-CG2 3.79Å; V233-V235 HydrophobicContact CG2-CG2 4.37Å; V233-V235 PolarHBondContact O-N 2.97Å; V235-D237 VanDerWaalsContact C-N 3.28Å; V235-D237 PolarHBondContact O-N 2.71Å; V235-Y432 WeakPolarHBondContact O-CE2 3.29Å; V235-Y432 PolarHBondContact O-OH 3.09Å
236A98.2Very high96.8Very high0 Ų014.2 Ų14.20%06%0.062CC..THydrogen-bonded Turntrans53.436-174.100000115V78 V80 L118 L121 I136 H224 R234 P238 I241V78-A236 HydrophobicContact CG1-CB 4.27Å; V80-A236 HydrophobicContact CG1-CB 3.6Å; L118-A236 HydrophobicContact CD2-CB 4.09Å; L121-A236 HydrophobicContact CD1-CB 3.69Å; I136-A236 HydrophobicContact CD1-CB 4.15Å; I136-A236 HydrophobicContact CG2-CB 4.44Å; H224-A236 WeakPolarHBondContact ND1-CA 3.4Å; H224-A236 PolarHBondContact ND1-N 3.04Å; R234-A236 PolarHBondContact O-N 2.63Å; A236-P238 WeakPolarHBondContact O-CD 3.18Å; A236-I241 WeakPolarHBondContact O-CD1 3.46Å
237D98Very high96.4Very high3 Ų316.3 Ų16.32%0.0167%0.072CC..  trans-47.1110.1-177.6-174.4-3.9000114R54 R234 V235 W239 F240 I241 K254 Y432R54-D237 IonicContact NH1-OD1 2.9Å; R54-D237 IonicContact NH1-OD2 2.94Å; R54-D237 PolarHBondContact NH1-OD2 2.86Å; R54-D237 VanDerWaalsContact NH1-OD2 3.1Å; R234-D237 HydrophobicContact CB-CB 3.87Å; R234-D237 WeakPolarHBondContact O-CB 3.34Å; R234-D237 PolarHBondContact O-N 3.22Å; R234-D237 VanDerWaalsContact O-N 3.08Å; V235-D237 VanDerWaalsContact C-N 3.28Å; V235-D237 PolarHBondContact O-N 2.71Å; D237-W239 VanDerWaalsContact C-N 3.27Å; D237-W239 PolarHBondContact O-N 3.42Å; D237-W239 WeakPolarHBondContact OD1-CB 3.44Å; D237-W239 PolarHBondContact OD1-N 3.25Å; D237-F240 HydrophobicContact CB-CB 3.9Å; D237-F240 PolarHBondContact O-N 3.32Å; D237-I241 WeakPolarHBondContact O-CD1 3.47Å; D237-I241 VanDerWaalsContact O-CG1 3.32Å; D237-I241 WeakPolarHBondContact O-CG1 3.31Å; D237-I241 PolarHBondContact O-N 3.05Å; D237-K254 IonicContact OD2-NZ 3.24Å; D237-K254 PolarHBondContact OD2-NZ 2.91Å; D237-Y432 VanDerWaalsContact CA-OH 3.27Å; D237-Y432 WeakPolarHBondContact CA-OH 3.49Å; D237-Y432 PolarHBondContact N-OH 2.82Å
238P97.5Very high96.4Very high10 Ų1019.8 Ų19.87%0.0659%0.089CC..Hα-helixtrans-57.3-39.9178-22.932.3000112.4G69 M70 I73 L121 A236 F240 I241 G242G69-P238 WeakPolarHBondContact CA-O 3.46Å; M70-P238 HydrophobicContact CG-CB 3.88Å; M70-P238 HydrophobicContact CG-CG 4.16Å; M70-P238 HydrophobicContact SD-CB 3.9Å; M70-P238 HydrophobicContact SD-CG 3.51Å; M70-P238 VanDerWaalsContact SD-CG 3.51Å; I73-P238 HydrophobicContact CD1-CB 4.37Å; I73-P238 HydrophobicContact CD1-CG 3.82Å; L121-P238 HydrophobicContact CD2-CG 3.73Å; A236-P238 WeakPolarHBondContact O-CD 3.18Å; P238-F240 VanDerWaalsContact C-N 3.34Å; P238-F240 PolarHBondContact O-N 3.48Å; P238-I241 PolarHBondContact O-N 2.97Å; P238-G242 PolarHBondContact O-N 2.9Å
239W95.7Very high96.4Very high4 Ų419.5 Ų19.52%0.0159%0.088CC..Hα-helixtrans-63.6-44.4-178.8-160.8106.8000110.4R54 E57 N62 F65 D237 I241 G242 F243 L370R54-W239 HydrophobicContact CB-CH2 4.12Å; R54-W239 HydrophobicContact CB-CZ2 4.3Å; R54-W239 HydrophobicContact CG-CD2 4.27Å; R54-W239 HydrophobicContact CG-CE3 4.46Å; R54-W239 HydrophobicContact CG-CH2 4.01Å; R54-W239 HydrophobicContact CG-CZ2 3.75Å; R54-W239 HydrophobicContact CG-CZ3 4.38Å; R54-W239 VanDerWaalsContact NH2-CB 3.28Å; E57-W239 HydrophobicContact CG-CH2 4.45Å; E57-W239 HydrophobicContact CG-CZ2 4.49Å; N62-W239 VanDerWaalsContact OD1-CZ2 3.3Å; N62-W239 WeakPolarHBondContact OD1-CZ2 3.35Å; N62-W239 PolarHBondContact OD1-NE1 3.39Å; F65-W239 HydrophobicContact CB-CD2 4.09Å; F65-W239 HydrophobicContact CB-CG 4.21Å; F65-W239 HydrophobicContact CD2-CD2 4.06Å; F65-W239 AromaticContact CD2-CE2 3.7Å; F65-W239 HydrophobicContact CD2-CE3 4.09Å; F65-W239 AromaticContact CD2-CH2 3.48Å; F65-W239 HydrophobicContact CD2-CH2 3.48Å; F65-W239 VanDerWaalsContact CD2-CH2 3.48Å; F65-W239 AromaticContact CD2-CZ2 3.45Å; F65-W239 HydrophobicContact CD2-CZ2 3.45Å; F65-W239 VanDerWaalsContact CD2-CZ2 3.45Å; F65-W239 AromaticContact CD2-CZ3 3.77Å; F65-W239 HydrophobicContact CD2-CZ3 3.77Å; F65-W239 AromaticContact CE2-CH2 3.76Å; F65-W239 HydrophobicContact CE2-CH2 3.76Å; F65-W239 AromaticContact CE2-CZ2 3.97Å; F65-W239 HydrophobicContact CE2-CZ2 3.97Å; F65-W239 HydrophobicContact CE2-CZ3 4.27Å; D237-W239 VanDerWaalsContact C-N 3.27Å; D237-W239 PolarHBondContact O-N 3.42Å; D237-W239 WeakPolarHBondContact OD1-CB 3.44Å; D237-W239 PolarHBondContact OD1-N 3.25Å; W239-I241 PolarHBondContact O-N 3.25Å; W239-G242 PolarHBondContact O-N 3.31Å; W239-F243 HydrophobicContact CE3-CB 4.01Å; W239-F243 HydrophobicContact CZ3-CB 3.78Å; W239-F243 HydrophobicContact CZ3-CD2 4.31Å; W239-F243 HydrophobicContact CZ3-CG 4.15Å; W239-F243 WeakPolarHBondContact O-CB 3.14Å; W239-F243 PolarHBondContact O-N 2.89Å; W239-L370 HydrophobicContact CE3-CD1 4.29Å; W239-L370 HydrophobicContact CE3-CD2 3.66Å; W239-L370 HydrophobicContact CH2-CD1 3.84Å; W239-L370 HydrophobicContact CZ3-CD1 3.33Å; W239-L370 HydrophobicContact CZ3-CD2 3.52Å; W239-L370 HydrophobicContact CZ3-CG 4.06Å
240F97.5Very high96.5Very high0 Ų019.7 Ų19.70%09%0.089CC..Hα-helixtrans-64.1-41.2177-174.8-147.4000112.3D237 P238 F243 C244 A252 K254 L308 L370D237-F240 HydrophobicContact CB-CB 3.9Å; D237-F240 PolarHBondContact O-N 3.32Å; P238-F240 VanDerWaalsContact C-N 3.34Å; P238-F240 PolarHBondContact O-N 3.48Å; F240-F243 HydrophobicContact CD2-CD1 4.16Å; F240-F243 HydrophobicContact CE2-CD1 4.38Å; F240-F243 PolarHBondContact O-N 3.36Å; F240-C244 PolarHBondContact O-N 3.42Å; F240-C244 PolarHBondContact O-SG 3.39Å; F240-A252 HydrophobicContact CE2-CB 3.76Å; F240-A252 HydrophobicContact CZ-CB 3.88Å; F240-K254 VanDerWaalsContact CB-CE 3.47Å; F240-K254 HydrophobicContact CD1-CD 4.3Å; F240-K254 VanDerWaalsContact CD1-CE 3.43Å; F240-K254 HydrophobicContact CD1-CG 4.15Å; F240-K254 HydrophobicContact CD2-CG 4.23Å; F240-K254 HydrophobicContact CE1-CG 3.98Å; F240-K254 HydrophobicContact CE2-CG 4.08Å; F240-K254 HydrophobicContact CG-CD 4.46Å; F240-K254 HydrophobicContact CG-CG 4.27Å; F240-K254 HydrophobicContact CZ-CG 3.96Å; F240-L308 HydrophobicContact CD1-CB 4.07Å; F240-L308 HydrophobicContact CD1-CD1 4.46Å; F240-L308 HydrophobicContact CE1-CB 3.49Å; F240-L308 VanDerWaalsContact CE1-CB 3.49Å; F240-L308 HydrophobicContact CE2-CB 4.42Å; F240-L308 HydrophobicContact CZ-CB 3.69Å; F240-L370 HydrophobicContact CB-CD2 4.23Å; F240-L370 HydrophobicContact CD2-CB 4.26Å; F240-L370 HydrophobicContact CD2-CD2 3.61Å; F240-L370 HydrophobicContact CE2-CB 4.21Å; F240-L370 HydrophobicContact CE2-CD2 4.37Å; F240-L370 HydrophobicContact CG-CD2 4.25Å
241I98.4Very high96.5Very high0 Ų019.5 Ų19.50%09%0.087CC..Hα-helixtrans-62.3-47.5175.4-64.7158.1000110.4A72 I73 V78 Y222 A236 D237 P238 W239 C244 R245 L308A72-I241 HydrophobicContact CB-CG2 3.98Å; I73-I241 HydrophobicContact CD1-CD1 4.5Å; I73-I241 HydrophobicContact CG1-CD1 4.46Å; V78-I241 HydrophobicContact CB-CD1 4.47Å; V78-I241 HydrophobicContact CG1-CD1 3.67Å; V78-I241 HydrophobicContact CG2-CD1 3.94Å; V78-I241 HydrophobicContact CG2-CG2 4.37Å; Y222-I241 HydrophobicContact CD2-CG2 4.17Å; Y222-I241 HydrophobicContact CG-CG2 4.23Å; A236-I241 WeakPolarHBondContact O-CD1 3.46Å; D237-I241 WeakPolarHBondContact O-CD1 3.47Å; D237-I241 VanDerWaalsContact O-CG1 3.32Å; D237-I241 WeakPolarHBondContact O-CG1 3.31Å; D237-I241 PolarHBondContact O-N 3.05Å; P238-I241 PolarHBondContact O-N 2.97Å; W239-I241 PolarHBondContact O-N 3.25Å; I241-C244 PolarHBondContact O-N 2.8Å; I241-R245 HydrophobicContact CG2-CG 4.45Å; I241-R245 VanDerWaalsContact O-CG 3.28Å; I241-R245 WeakPolarHBondContact O-CG 3.33Å; I241-R245 PolarHBondContact O-N 2.99Å; I241-L308 HydrophobicContact CB-CD1 4.11Å; I241-L308 HydrophobicContact CG1-CD1 3.62Å
242G97.1Very high96.5Very high0 Ų019.4 Ų19.40%09%0.087CC..Hα-helixtrans-62.8-41.617800000113.5F65 P238 W239 C244 R245 R246F65-G242 VanDerWaalsContact O-CA 3.3Å; F65-G242 WeakPolarHBondContact O-CA 3.22Å; P238-G242 PolarHBondContact O-N 2.9Å; W239-G242 PolarHBondContact O-N 3.31Å; G242-C244 PolarHBondContact O-N 3.24Å; G242-R245 WeakPolarHBondContact O-CB 3.31Å; G242-R245 PolarHBondContact O-N 2.97Å; G242-R246 WeakPolarHBondContact O-CB 3.33Å; G242-R246 PolarHBondContact O-N 2.96Å
243F95Very high96.5Very high1 Ų119.2 Ų19.20%0.0049%0.086CC..Hα-helixtrans-55.7-50.2171.4166.7-103.2000111.2C52 F65 W239 F240 R245 R246 M247 A368 L370C52-F243 HydrophobicContact CB-CD2 4.08Å; C52-F243 HydrophobicContact CB-CE2 3.35Å; C52-F243 HydrophobicContact CB-CZ 3.9Å; F65-F243 HydrophobicContact CD2-CB 4.1Å; F65-F243 HydrophobicContact CE2-CB 4.44Å; F65-F243 HydrophobicContact CE2-CD2 4.11Å; F65-F243 HydrophobicContact CG-CB 4.4Å; W239-F243 HydrophobicContact CE3-CB 4.01Å; W239-F243 HydrophobicContact CZ3-CB 3.78Å; W239-F243 HydrophobicContact CZ3-CD2 4.31Å; W239-F243 HydrophobicContact CZ3-CG 4.15Å; W239-F243 WeakPolarHBondContact O-CB 3.14Å; W239-F243 PolarHBondContact O-N 2.89Å; F240-F243 HydrophobicContact CD2-CD1 4.16Å; F240-F243 HydrophobicContact CE2-CD1 4.38Å; F240-F243 PolarHBondContact O-N 3.36Å; F243-R245 VanDerWaalsContact C-N 3.32Å; F243-R245 PolarHBondContact O-N 3.48Å; F243-R246 PolarHBondContact O-N 3.46Å; F243-M247 HydrophobicContact CD2-CG 3.96Å; F243-M247 HydrophobicContact CE2-CE 4.26Å; F243-M247 HydrophobicContact CE2-CG 3.56Å; F243-M247 HydrophobicContact CZ-CG 3.9Å; F243-M247 WeakPolarHBondContact O-CB 3.43Å; F243-M247 WeakPolarHBondContact O-CG 3.39Å; F243-M247 PolarHBondContact O-N 3.44Å; F243-A368 HydrophobicContact CE1-CB 3.75Å; F243-A368 HydrophobicContact CZ-CB 3.93Å; F243-L370 HydrophobicContact CD1-CB 4.16Å; F243-L370 HydrophobicContact CD1-CD2 4.41Å; F243-L370 HydrophobicContact CE1-CB 3.96Å
244C96Very high96.4Very high0 Ų019.2 Ų19.20%09%0.086CC..Hα-helixtrans-63.2-39.5179.2-64.70000112.1F240 I241 G242 M247 D248 A249 A252 L308F240-C244 PolarHBondContact O-N 3.42Å; F240-C244 PolarHBondContact O-SG 3.39Å; I241-C244 PolarHBondContact O-N 2.8Å; G242-C244 PolarHBondContact O-N 3.24Å; C244-M247 PolarHBondContact O-N 3.43Å; C244-D248 PolarHBondContact O-N 2.95Å; C244-A249 HydrophobicContact CB-CB 4.26Å; C244-A249 PolarHBondContact O-N 2.92Å; C244-A252 WeakPolarHBondContact SG-CB 3.47Å; C244-L308 HydrophobicContact CB-CD1 4.01Å; C244-L308 HydrophobicContact CB-CD2 3.63Å; C244-L308 HydrophobicContact CB-CG 4.35Å
245R95Very high96.4Very high65 Ų6518.3 Ų18.325%0.2458%0.082CC..Hα-helixtrans-60.5-46.8174-72.5-175.571.2-154.8-8.1111.6L68 Y222 I241 G242 F243 M247 D248L68-R245 PolarHBondContact O-NH1 3Å; Y222-R245 HydrophobicContact CE1-CG 3.77Å; Y222-R245 HydrophobicContact CE2-CG 3.89Å; Y222-R245 VanDerWaalsContact CZ-CG 3.42Å; Y222-R245 WeakPolarHBondContact OH-CG 3.29Å; I241-R245 HydrophobicContact CG2-CG 4.45Å; I241-R245 VanDerWaalsContact O-CG 3.28Å; I241-R245 WeakPolarHBondContact O-CG 3.33Å; I241-R245 PolarHBondContact O-N 2.99Å; G242-R245 WeakPolarHBondContact O-CB 3.31Å; G242-R245 PolarHBondContact O-N 2.97Å; F243-R245 VanDerWaalsContact C-N 3.32Å; F243-R245 PolarHBondContact O-N 3.48Å; R245-M247 VanDerWaalsContact C-N 3.32Å; R245-M247 PolarHBondContact O-N 3.05Å; R245-D248 PolarHBondContact O-N 2.64Å
246R92Very high96.2Very high136 Ų13618.3 Ų18.351%0.5138%0.082SC..Hα-helixtrans-64.6-39.7179.6-175.465.4162.878.93.2112.2E64 F65 L68 G242 F243 D248E64-R246 VanDerWaalsContact OE1-CD 3.23Å; E64-R246 WeakPolarHBondContact OE1-CD 3.38Å; E64-R246 IonicContact OE1-NE 2.69Å; E64-R246 PolarHBondContact OE1-NE 3.46Å; F65-R246 HydrophobicContact CD1-CB 4.16Å; F65-R246 HydrophobicContact CE1-CB 3.72Å; F65-R246 HydrophobicContact CE1-CG 3.7Å; F65-R246 HydrophobicContact CZ-CG 4.39Å; L68-R246 HydrophobicContact CD1-CB 4.45Å; G242-R246 WeakPolarHBondContact O-CB 3.33Å; G242-R246 PolarHBondContact O-N 2.96Å; F243-R246 PolarHBondContact O-N 3.46Å; R246-D248 PolarHBondContact O-N 3.28Å
247M90.6Very high95.9Very high45 Ų4520.6 Ų20.622%0.2229%0.093CC..Hα-helixtrans-80.3-6-179.9-65.9-42.1-126.800113.6K50 F243 C244 R245 A249K50-M247 HydrophobicContact CB-CE 3.66Å; K50-M247 HydrophobicContact CB-CG 4.46Å; K50-M247 HydrophobicContact CD-CB 3.84Å; K50-M247 HydrophobicContact CD-CE 3.76Å; K50-M247 HydrophobicContact CD-CG 4.07Å; K50-M247 HydrophobicContact CD-SD 3.88Å; K50-M247 HydrophobicContact CG-CE 3.79Å; K50-M247 PolarHBondContact NZ-O 2.99Å; F243-M247 HydrophobicContact CD2-CG 3.96Å; F243-M247 HydrophobicContact CE2-CE 4.26Å; F243-M247 HydrophobicContact CE2-CG 3.56Å; F243-M247 HydrophobicContact CZ-CG 3.9Å; F243-M247 WeakPolarHBondContact O-CB 3.43Å; F243-M247 WeakPolarHBondContact O-CG 3.39Å; F243-M247 PolarHBondContact O-N 3.44Å; C244-M247 PolarHBondContact O-N 3.43Å; R245-M247 VanDerWaalsContact C-N 3.32Å; R245-M247 PolarHBondContact O-N 3.05Å; M247-A249 HydrophobicContact CB-CB 4.34Å; M247-A249 PolarHBondContact O-N 3.46Å
248D94.9Very high95.6Very high96 Ų9620.8 Ų20.851%0.5139%0.094SC..THydrogen-bonded Turntrans5141.6-171.6-168.931.9000110.7C244 R245 R246 K366C244-D248 PolarHBondContact O-N 2.95Å; R245-D248 PolarHBondContact O-N 2.64Å; R246-D248 PolarHBondContact O-N 3.28Å; D248-K366 HydrophobicContact CB-CD 4.39Å; D248-K366 VanDerWaalsContact O-CB 3.3Å; D248-K366 WeakPolarHBondContact O-CB 3.4Å; D248-K366 WeakPolarHBondContact O-CD 3.5Å; D248-K366 IonicContact OD2-NZ 3.19Å; D248-K366 PolarHBondContact OD2-NZ 3.46Å
249A96.2Very high95Very high3 Ų326.8 Ų26.83%0.02512%0.121CC..  trans-80125.4-175.400000110C244 M247 A252 T310 K366 A368C244-A249 HydrophobicContact CB-CB 4.26Å; C244-A249 PolarHBondContact O-N 2.92Å; M247-A249 HydrophobicContact CB-CB 4.34Å; M247-A249 PolarHBondContact O-N 3.46Å; A249-A252 HydrophobicContact CB-CB 4.34Å; A249-T310 WeakPolarHBondContact O-CG2 3.4Å; A249-K366 WeakPolarHBondContact CA-O 3.3Å; A249-K366 WeakPolarHBondContact CB-O 3.45Å; A249-A368 HydrophobicContact CB-CB 3.79Å
250D97.4Very high94.7Very high21 Ų2130.4 Ų30.411%0.11214%0.14CC..SBendtrans-83.1-26.4175.162.40.4000112T310 F313 S364 K365 K366D250-T310 PolarHBondContact O-N 3.36Å; D250-T310 PolarHBondContact O-OG1 2.95Å; D250-F313 HydrophobicContact CB-CB 4.22Å; D250-F313 HydrophobicContact CB-CD2 4.39Å; D250-F313 WeakPolarHBondContact O-CB 3.44Å; D250-S364 WeakPolarHBondContact OD1-CB 3.41Å; D250-S364 PolarHBondContact OD1-OG 3Å; D250-K365 WeakPolarHBondContact OD2-CB 3.45Å; D250-K365 PolarHBondContact OD2-N 3.42Å; D250-K366 PolarHBondContact N-O 3.34Å; D250-K366 PolarHBondContact OD1-N 2.92Å; D250-K366 VanDerWaalsContact OD1-N 3.12Å; D250-K366 PolarHBondContact OD2-N 3.27Å
251C97.8Very high94.3Very high0 Ų031.7 Ų31.70%015%0.148CC..EExtended strand (participates in β ladder)trans-143.1129.9175.4175.20000109.2L308 F309 F313 F367 A368C251-L308 CarbonylContact C-O 3.52Å; C251-L308 WeakPolarHBondContact CA-O 3.29Å; C251-F309 HydrophobicContact CB-CD1 4.06Å; C251-F309 HydrophobicContact CB-CE1 4.34Å; C251-F309 WeakPolarHBondContact SG-CE1 3.47Å; C251-F313 HydrophobicContact CB-CD1 4.31Å; C251-F313 HydrophobicContact CB-CE1 4.05Å; C251-F313 HydrophobicContact CB-CE2 4.39Å; C251-F313 HydrophobicContact CB-CZ 4.09Å; C251-F367 HydrophobicContact CB-CD2 4.12Å; C251-F367 VanDerWaalsContact O-CA 3.32Å; C251-F367 WeakPolarHBondContact O-CA 3.29Å; C251-A368 PolarHBondContact O-N 2.83Å; C251-A368 VanDerWaalsContact O-N 3.11Å
252A97.7Very high93.9Very high0 Ų036.5 Ų36.50%017%0.17CC..EExtended strand (participates in β ladder)trans-138.9156174.700000111.5F240 C244 A249 H307 L308 A368F240-A252 HydrophobicContact CE2-CB 3.76Å; F240-A252 HydrophobicContact CZ-CB 3.88Å; C244-A252 WeakPolarHBondContact SG-CB 3.47Å; A249-A252 HydrophobicContact CB-CB 4.34Å; A252-H307 CarbonylContact O-C 3.41Å; A252-H307 WeakPolarHBondContact O-CA 3.29Å; A252-L308 PolarHBondContact N-O 3.09Å; A252-L308 PolarHBondContact O-N 2.79Å; A252-A368 WeakPolarHBondContact CA-O 3.05Å; A252-A368 HydrophobicContact CB-CB 4.08Å
253V97.7Very high93.6Very high0 Ų037.9 Ų37.90%018%0.176CC..EExtended strand (participates in β ladder)trans-133.8141.9178.864.30000110.2I268 N303 N306 F361 F367 A368 V369 L370V253-I268 HydrophobicContact CB-CD1 4.46Å; V253-I268 HydrophobicContact CG1-CD1 3.56Å; V253-I268 HydrophobicContact CG1-CG1 4.17Å; V253-I268 HydrophobicContact CG2-CD1 4.02Å; V253-N303 VanDerWaalsContact CG2-OD1 3.32Å; V253-N303 WeakPolarHBondContact CG2-OD1 3.44Å; V253-N306 CarbonylContact C-O 3.49Å; V253-N306 WeakPolarHBondContact CA-O 3.41Å; V253-F361 HydrophobicContact CB-CE2 4.36Å; V253-F361 HydrophobicContact CB-CZ 3.94Å; V253-F361 HydrophobicContact CG1-CE2 4.31Å; V253-F361 HydrophobicContact CG1-CZ 4.37Å; V253-F361 HydrophobicContact CG2-CE2 4.47Å; V253-F361 HydrophobicContact CG2-CZ 4.04Å; V253-F367 HydrophobicContact CB-CZ 4.29Å; V253-F367 HydrophobicContact CG1-CE1 4.13Å; V253-F367 HydrophobicContact CG1-CE2 4.28Å; V253-F367 HydrophobicContact CG1-CZ 3.48Å; V253-F367 VanDerWaalsContact CG1-CZ 3.48Å; V253-A368 PolarHBondContact N-O 3.14Å; V253-V369 HydrophobicContact CG1-CB 4.47Å; V253-V369 HydrophobicContact CG1-CG1 4.43Å; V253-V369 HydrophobicContact CG1-CG2 3.89Å; V253-V369 WeakPolarHBondContact O-CA 3.47Å; V253-L370 PolarHBondContact O-N 3.3Å
254K97.5Very high93.4Very high0 Ų041.7 Ų41.70%020%0.201CC..EExtended strand (participates in β ladder)trans-84.1138165.7-63.6-174.2174.4-176.60110.4D237 F240 I304 N306 L370 V372 E377D237-K254 IonicContact OD2-NZ 3.24Å; D237-K254 PolarHBondContact OD2-NZ 2.91Å; F240-K254 VanDerWaalsContact CB-CE 3.47Å; F240-K254 HydrophobicContact CD1-CD 4.3Å; F240-K254 VanDerWaalsContact CD1-CE 3.43Å; F240-K254 HydrophobicContact CD1-CG 4.15Å; F240-K254 HydrophobicContact CD2-CG 4.23Å; F240-K254 HydrophobicContact CE1-CG 3.98Å; F240-K254 HydrophobicContact CE2-CG 4.08Å; F240-K254 HydrophobicContact CG-CD 4.46Å; F240-K254 HydrophobicContact CG-CG 4.27Å; F240-K254 HydrophobicContact CZ-CG 3.96Å; K254-I304 HydrophobicContact CB-CD1 3.92Å; K254-I304 HydrophobicContact CB-CG1 4.05Å; K254-I304 WeakPolarHBondContact O-CG1 3.19Å; K254-N306 HydrophobicContact CB-CB 4.16Å; K254-N306 HydrophobicContact CD-CB 4.32Å; K254-N306 WeakPolarHBondContact CD-OD1 3.33Å; K254-N306 HydrophobicContact CG-CB 4.43Å; K254-N306 PolarHBondContact N-O 3.47Å; K254-L370 CarbonylContact C-O 3.51Å; K254-L370 VanDerWaalsContact CA-O 3.23Å; K254-L370 WeakPolarHBondContact CA-O 3.41Å; K254-V372 HydrophobicContact CB-CG1 4.44Å; K254-V372 HydrophobicContact CB-CG2 4.37Å; K254-V372 HydrophobicContact CD-CG1 3.97Å; K254-V372 HydrophobicContact CD-CG2 4.47Å; K254-V372 HydrophobicContact CG-CG1 4.23Å; K254-E377 IonicContact NZ-OE1 3.69Å; K254-E377 IonicContact NZ-OE2 3.04Å; K254-E377 PolarHBondContact NZ-OE2 3.01Å
255S96.1Very high93.2Very high0 Ų042.2 Ų42.20%020%0.204CC..EExtended strand (participates in β ladder)trans-120.4158.5173.5640000111.3Q301 G302 V369 L370 E371 V372S255-Q301 VanDerWaalsContact CB-OE1 3.25Å; S255-Q301 PolarHBondContact OG-OE1 3.22Å; S255-G302 WeakPolarHBondContact CA-O 3.32Å; S255-G302 WeakPolarHBondContact CB-O 3.33Å; S255-V369 WeakPolarHBondContact OG-CG1 3.32Å; S255-L370 PolarHBondContact N-O 3.44Å; S255-E371 WeakPolarHBondContact O-CA 3.35Å; S255-E371 VanDerWaalsContact OG-CA 3.3Å; S255-E371 WeakPolarHBondContact OG-CA 3.25Å; S255-V372 WeakPolarHBondContact O-CG2 3.45Å; S255-V372 PolarHBondContact O-N 2.8Å
256V94.6Very high93.1Very high0 Ų039.3 Ų39.30%019%0.194CC..EExtended strand (participates in β ladder)trans-123.6150.4166.4-64.60000109.2R258 I265 G302 I304 V372 R374 F378V256-R258 PolarHBondContact O-N 3.19Å; V256-I265 HydrophobicContact CG2-CD1 4.22Å; V256-G302 PolarHBondContact N-O 3.49Å; V256-G302 PolarHBondContact O-N 2.94Å; V256-I304 HydrophobicContact CB-CG2 4.2Å; V256-I304 HydrophobicContact CG1-CD1 4.29Å; V256-I304 HydrophobicContact CG1-CG2 3.78Å; V256-I304 HydrophobicContact CG2-CG2 3.48Å; V256-I304 VanDerWaalsContact CG2-CG2 3.48Å; V256-V372 HydrophobicContact CG1-CG2 4Å; V256-R374 HydrophobicContact CB-CB 4.29Å; V256-R374 HydrophobicContact CG1-CB 4.2Å; V256-F378 HydrophobicContact CG1-CB 3.86Å; V256-F378 HydrophobicContact CG1-CD1 4.43Å; V256-F378 HydrophobicContact CG1-CG 4.37Å; V256-F378 HydrophobicContact CG2-CD1 3.93Å; V256-F378 HydrophobicContact CG2-CE1 4.35Å
257E92.3Very high93.1Very high48 Ų4832.9 Ų32.922%0.22417%0.17CC..EExtended strand (participates in β ladder)trans-65.1128.4170.7-172.3166.2-161.700109.5R296 S300 R374E257-R296 IonicContact OE1-CZ 3.84Å; E257-R296 IonicContact OE1-NE 3.49Å; E257-R296 PolarHBondContact OE1-NE 3.47Å; E257-R296 IonicContact OE1-NH2 2.78Å; E257-R296 PolarHBondContact OE1-NH2 3.19Å; E257-R296 IonicContact OE2-CZ 3.06Å; E257-R296 IonicContact OE2-NH2 3.63Å; E257-R296 PolarHBondContact OE2-NH2 2.86Å; E257-S300 WeakPolarHBondContact CA-O 3.37Å; E257-R374 PolarHBondContact O-NE 3.06Å; E257-R374 PolarHBondContact O-NH2 3.42Å
258R90.8Very high93.1Very high7 Ų731.6 Ų31.63%0.02616%0.164CC..  trans-76.7122.6171.7-68.1174.766.2-1467.4109.2V256 N260 P261 E263 I265 L297 L299 S300V256-R258 PolarHBondContact O-N 3.19Å; R258-N260 PolarHBondContact NH2-O 2.62Å; R258-P261 PolarHBondContact NH2-O 2.86Å; R258-E263 PolarHBondContact NH2-O 3.35Å; R258-I265 HydrophobicContact CG-CG2 3.71Å; R258-L297 HydrophobicContact CB-CD1 4.35Å; R258-L299 WeakPolarHBondContact CD-O 3.18Å; R258-L299 PolarHBondContact NH1-O 3.28Å; R258-S300 WeakPolarHBondContact CG-O 3.32Å; R258-S300 PolarHBondContact N-O 3.1Å
259H84.9Confident92.7Very high136 Ų13628.1 Ų28.163%0.6315%0.146SC*.SBendtrans-87.8-20.1175.8-57.5-66000112.2R374H259-R374 PolarHBondContact CD2-NE 3.04Å; H259-R374 PolarHBondContact NE2-NE 2.87Å
260N89.5Confident92.1Very high80 Ų8029 Ų2943%0.42815%0.15SC..SBendtrans-123.7124.3179.9-176.5-15.3000110.2R258 F262 E263R258-N260 PolarHBondContact NH2-O 2.62Å; N260-F262 PolarHBondContact O-N 3.1Å; N260-F262 PolarHBondContact OD1-N 3.03Å; N260-E263 HydrophobicContact CB-CB 4.23Å; N260-E263 VanDerWaalsContact O-CB 3.29Å; N260-E263 WeakPolarHBondContact O-CB 3.41Å; N260-E263 PolarHBondContact O-N 3.32Å
261P88.2Confident91.1Very high27 Ų2734 Ų3418%0.17517%0.171CC..THydrogen-bonded Turntrans-49-26.3171-31.937.7000115.2R258 A288 Q289 L297R258-P261 PolarHBondContact NH2-O 2.86Å; P261-A288 HydrophobicContact CB-CB 4.44Å; P261-A288 WeakPolarHBondContact CB-O 3.26Å; P261-A288 WeakPolarHBondContact O-CB 3.36Å; P261-Q289 HydrophobicContact CB-CG 3.81Å; P261-Q289 HydrophobicContact CG-CG 4.13Å; P261-L297 HydrophobicContact CG-CD1 4.07Å; P261-L297 HydrophobicContact CG-CD2 3.8Å
262F91.2Very high90.3Very high102 Ų10239.7 Ų39.745%0.44720%0.201SC..THydrogen-bonded Turntrans-110.613.5-176.9-49.9-62.8000112.8N260 Q285 A288 Q289N260-F262 PolarHBondContact O-N 3.1Å; N260-F262 PolarHBondContact OD1-N 3.03Å; F262-Q285 HydrophobicContact CE1-CB 4.05Å; F262-Q285 HydrophobicContact CE1-CG 3.95Å; F262-A288 HydrophobicContact CE1-CB 4.48Å; F262-Q289 HydrophobicContact CE1-CG 4.21Å; F262-Q289 HydrophobicContact CE2-CG 4.27Å; F262-Q289 HydrophobicContact CZ-CG 3.65Å
263E91.3Very high89.4Confident28 Ų2841.8 Ų41.813%0.13122%0.223CC..  trans-56.6128.3169.6-171.6178178.100109.2R258 N260 I265 R374R258-E263 PolarHBondContact NH2-O 3.35Å; N260-E263 HydrophobicContact CB-CB 4.23Å; N260-E263 VanDerWaalsContact O-CB 3.29Å; N260-E263 WeakPolarHBondContact O-CB 3.41Å; N260-E263 PolarHBondContact O-N 3.32Å; E263-I265 HydrophobicContact CB-CG2 4.05Å; E263-I265 HydrophobicContact CG-CB 4.29Å; E263-I265 HydrophobicContact CG-CG2 3.78Å; E263-I265 PolarHBondContact O-N 3.16Å; E263-R374 VanDerWaalsContact CD-NH2 3.32Å; E263-R374 IonicContact OE1-CZ 2.71Å; E263-R374 VanDerWaalsContact OE1-CZ 3.24Å; E263-R374 IonicContact OE1-NH1 2.63Å; E263-R374 PolarHBondContact OE1-NH1 2.9Å; E263-R374 IonicContact OE1-NH2 2.68Å; E263-R374 PolarHBondContact OE1-NH2 3.07Å; E263-R374 IonicContact OE2-CZ 2.69Å; E263-R374 IonicContact OE2-NH2 3.38Å; E263-R374 PolarHBondContact OE2-NH2 3.13Å
264P90.6Very high89Confident81 Ų8147.2 Ų47.253%0.52625%0.246SC..SBendtrans-7861.5-175.334-37.2000111.5Y280P264-Y280 VanDerWaalsContact C-CD1 3.41Å; P264-Y280 HydrophobicContact CB-CD1 4.12Å; P264-Y280 HydrophobicContact CB-CD2 4.11Å; P264-Y280 HydrophobicContact CB-CE1 3.95Å; P264-Y280 HydrophobicContact CB-CE2 3.95Å; P264-Y280 HydrophobicContact CB-CG 4.2Å
265I91.6Very high88.7Confident12 Ų1248.1 Ų48.16%0.06225%0.252CS..  trans-129.4133.2-178.3-168.5168000109V256 R258 E263 N303 I304 F378V256-I265 HydrophobicContact CG2-CD1 4.22Å; R258-I265 HydrophobicContact CG-CG2 3.71Å; E263-I265 HydrophobicContact CB-CG2 4.05Å; E263-I265 HydrophobicContact CG-CB 4.29Å; E263-I265 HydrophobicContact CG-CG2 3.78Å; E263-I265 PolarHBondContact O-N 3.16Å; I265-N303 VanDerWaalsContact CG1-O 3.31Å; I265-N303 WeakPolarHBondContact CG1-O 3.41Å; I265-I304 HydrophobicContact CD1-CG2 4Å; I265-F378 HydrophobicContact CD1-CE1 4.02Å; I265-F378 HydrophobicContact CD1-CZ 4.11Å
266G92.5Very high88.5Confident4 Ų448.8 Ų48.84%0.04126%0.257CS..  trans-61.6146.7173.500000110.9V278 N303G266-V278 CarbonylContact C-O 3.53Å; G266-V278 WeakPolarHBondContact CA-O 3.12Å; G266-N303 WeakPolarHBondContact O-CB 3.31Å; G266-N303 PolarHBondContact O-N 3.05Å
267V91.5Very high88.4Confident1 Ų149.4 Ų49.41%0.00626%0.261CS..EExtended strand (participates in β ladder)trans-107.6126.9-177.7-178.30000110C269 V277 V278 I283 L299 Q301V267-C269 PolarHBondContact O-N 3.1Å; V267-V277 VanDerWaalsContact O-CA 3.28Å; V267-V277 WeakPolarHBondContact O-CA 3.35Å; V267-V278 PolarHBondContact N-O 3.44Å; V267-V278 PolarHBondContact O-N 3.32Å; V267-I283 HydrophobicContact CB-CD1 4.11Å; V267-I283 HydrophobicContact CG2-CD1 3.6Å; V267-L299 HydrophobicContact CG1-CB 3.85Å; V267-L299 HydrophobicContact CG1-CD2 4.08Å; V267-L299 HydrophobicContact CG1-CG 4.44Å; V267-L299 HydrophobicContact CG2-CB 4.31Å; V267-Q301 WeakPolarHBondContact CA-O 3.42Å
268I92Very high88.2Confident18 Ų1848.7 Ų48.79%0.09226%0.26CS..EExtended strand (participates in β ladder)trans-71.2124.1172.3-59.7152.3000108.4V253 V277 Q301 N303 F367 V369V253-I268 HydrophobicContact CB-CD1 4.46Å; V253-I268 HydrophobicContact CG1-CD1 3.56Å; V253-I268 HydrophobicContact CG1-CG1 4.17Å; V253-I268 HydrophobicContact CG2-CD1 4.02Å; I268-V277 HydrophobicContact CG1-CG2 4.11Å; I268-Q301 HydrophobicContact CB-CB 4.22Å; I268-Q301 PolarHBondContact N-O 3.33Å; I268-N303 HydrophobicContact CD1-CB 4.25Å; I268-N303 HydrophobicContact CG1-CB 3.94Å; I268-F367 HydrophobicContact CG2-CE1 4.25Å; I268-V369 HydrophobicContact CD1-CG1 4.27Å; I268-V369 HydrophobicContact CG2-CG2 3.87Å
269C85.9Confident88.1Confident22 Ų2250 Ų5015%0.14927%0.267CS..EExtended strand (participates in β ladder)trans-146.2-170-17970.70000110.5V267 A276 V278V267-C269 PolarHBondContact O-N 3.1Å; C269-A276 PolarHBondContact N-O 3.45Å; C269-A276 PolarHBondContact O-N 3.21Å; C269-A276 VanDerWaalsContact O-O 3.13Å; C269-V278 WeakPolarHBondContact SG-CG2 3.36Å
270Q82.7Confident88.1Confident22 Ų2248.9 Ų48.910%0.10326%0.258CS..EExtended strand (participates in β ladder)trans-116138.6163.7-64-15915.600110.4V46 P47 K274V46-Q270 HydrophobicContact CB-CG 4.46Å; V46-Q270 HydrophobicContact CG1-CG 4.22Å; V46-Q270 HydrophobicContact CG2-CG 4.45Å; P47-Q270 VanDerWaalsContact CD-CD 3.41Å; P47-Q270 PolarHBondContact O-NE2 3.18Å; Q270-K274 CarbonylContact C-O 3.55Å; Q270-K274 VanDerWaalsContact CA-O 3.26Å; Q270-K274 WeakPolarHBondContact CA-O 3.37Å
271K77.9Confident87.8Confident126 Ų12649.4 Ų49.455%0.54827%0.268SS..EExtended strand (participates in β ladder)trans-126.8119.3175.3-175.2177-179.9177.60107.2G273 K274 A276K271-G273 PolarHBondContact O-N 3.48Å; K271-K274 PolarHBondContact N-O 3.03Å; K271-K274 PolarHBondContact O-N 2.95Å; K271-A276 HydrophobicContact CB-CB 3.87Å
272D80.1Confident87.5Confident120 Ų12053.5 Ų53.564%0.64228%0.284SS*.THydrogen-bonded Turntrans55.338.7-178.6-56.6-51.2000113.3A43 K274A43-D272 PolarHBondContact O-N 3.26Å; A43-D272 VanDerWaalsContact O-N 3.16Å; D272-K274 PolarHBondContact O-N 2.89Å
273G79.4Confident87Confident43 Ų4349.7 Ų49.744%0.44327%0.268SS..THydrogen-bonded Turntrans72.89.5179.900000115K271K271-G273 PolarHBondContact O-N 3.48Å
274K88.3Confident86.7Confident115 Ų11551.5 Ų51.550%0.528%0.284SS..EExtended strand (participates in β ladder)trans-114.7145.7175.3-64.9-169.8179.7-172.70110.8Q270 K271 D272 A276 P362Q270-K274 CarbonylContact C-O 3.55Å; Q270-K274 VanDerWaalsContact CA-O 3.26Å; Q270-K274 WeakPolarHBondContact CA-O 3.37Å; K271-K274 PolarHBondContact N-O 3.03Å; K271-K274 PolarHBondContact O-N 2.95Å; D272-K274 PolarHBondContact O-N 2.89Å; K274-A276 PolarHBondContact O-N 2.91Å; K274-P362 HydrophobicContact CB-CB 4.1Å; K274-P362 HydrophobicContact CD-CB 3.77Å
275P92Very high86.6Confident19 Ų1954.6 Ų54.612%0.12329%0.291CS..EExtended strand (participates in β ladder)trans-63.8136.317529.1-35.5000110.2F361 P362 F367P275-F361 HydrophobicContact CB-CB 4.19Å; P275-F361 HydrophobicContact CG-CB 4.15Å; P275-F361 WeakPolarHBondContact CG-O 3.09Å; P275-F361 WeakPolarHBondContact O-CB 3.48Å; P275-P362 WeakPolarHBondContact O-CD 3.47Å; P275-P362 WeakPolarHBondContact O-CG 3.24Å; P275-F367 HydrophobicContact CB-CB 4.21Å; P275-F367 HydrophobicContact CB-CD1 3.37Å; P275-F367 HydrophobicContact CB-CD2 4.22Å; P275-F367 HydrophobicContact CB-CE1 3.64Å; P275-F367 HydrophobicContact CB-CE2 4.45Å; P275-F367 HydrophobicContact CB-CG 3.67Å; P275-F367 HydrophobicContact CB-CZ 4.18Å; P275-F367 HydrophobicContact CG-CB 3.83Å; P275-F367 HydrophobicContact CG-CD1 3.97Å; P275-F367 HydrophobicContact CG-CD2 4.19Å; P275-F367 HydrophobicContact CG-CG 3.74Å
276A91.8Very high86.3Confident13 Ų1359 Ų5911%0.10731%0.312CS..EExtended strand (participates in β ladder)trans-148.8169.9-177.900000110.2C269 K271 K274C269-A276 PolarHBondContact N-O 3.45Å; C269-A276 PolarHBondContact O-N 3.21Å; C269-A276 VanDerWaalsContact O-O 3.13Å; K271-A276 HydrophobicContact CB-CB 3.87Å; K274-A276 PolarHBondContact O-N 2.91Å
277V92Very high86Confident13 Ų1361.5 Ų61.58%0.07932%0.324CS..EExtended strand (participates in β ladder)trans-120132.2164.2177.30000107.1V267 I268 N303 F358 F361V267-V277 VanDerWaalsContact O-CA 3.28Å; V267-V277 WeakPolarHBondContact O-CA 3.35Å; I268-V277 HydrophobicContact CG1-CG2 4.11Å; V277-N303 HydrophobicContact CG1-CB 4.15Å; V277-N303 HydrophobicContact CG2-CB 4.22Å; V277-F358 HydrophobicContact CB-CB 4.22Å; V277-F358 HydrophobicContact CB-CD1 4.16Å; V277-F358 HydrophobicContact CB-CD2 3.55Å; V277-F358 HydrophobicContact CB-CE1 4.37Å; V277-F358 HydrophobicContact CB-CE2 3.81Å; V277-F358 HydrophobicContact CB-CG 3.72Å; V277-F358 HydrophobicContact CB-CZ 4.2Å; V277-F358 HydrophobicContact CG1-CD1 4.24Å; V277-F358 HydrophobicContact CG1-CD2 4.3Å; V277-F358 HydrophobicContact CG1-CE1 4.11Å; V277-F358 HydrophobicContact CG1-CE2 4.19Å; V277-F358 HydrophobicContact CG1-CG 4.3Å; V277-F358 HydrophobicContact CG1-CZ 4.07Å; V277-F358 HydrophobicContact CG2-CB 3.7Å; V277-F358 HydrophobicContact CG2-CD1 4.25Å; V277-F358 HydrophobicContact CG2-CD2 4.03Å; V277-F358 HydrophobicContact CG2-CG 3.74Å; V277-F361 HydrophobicContact CG2-CD2 3.99Å; V277-F361 HydrophobicContact CG2-CE2 3.53Å
278V88.1Confident85.6Confident34 Ų3461.7 Ų61.721%0.20633%0.326CS..EExtended strand (participates in β ladder)trans-103.3123170.9177.20000107.1G266 V267 C269 E282 I283G266-V278 CarbonylContact C-O 3.53Å; G266-V278 WeakPolarHBondContact CA-O 3.12Å; V267-V278 PolarHBondContact N-O 3.44Å; V267-V278 PolarHBondContact O-N 3.32Å; C269-V278 WeakPolarHBondContact SG-CG2 3.36Å; V278-E282 HydrophobicContact CG1-CB 3.82Å; V278-I283 HydrophobicContact CB-CG1 4.41Å; V278-I283 HydrophobicContact CG1-CD1 4.29Å; V278-I283 HydrophobicContact CG1-CG1 3.6Å
279E87.8Confident85.6Confident35 Ų3565.7 Ų65.716%0.16434%0.344CS..  trans-67.8147.6179.8-80-62.112500110.7S281 E282 F356 F358E279-S281 PolarHBondContact O-N 3.43Å; E279-E282 HydrophobicContact CB-CG 4.25Å; E279-E282 WeakPolarHBondContact O-CB 3.38Å; E279-E282 PolarHBondContact O-N 2.95Å; E279-F356 HydrophobicContact CG-CD2 4.5Å; E279-F356 HydrophobicContact CG-CE2 4.03Å; E279-F358 HydrophobicContact CG-CZ 4.05Å; E279-F358 VanDerWaalsContact OE1-CE1 3.31Å; E279-F358 WeakPolarHBondContact OE1-CE1 3.23Å; E279-F358 WeakPolarHBondContact OE1-CZ 3.34Å
280Y85.4Confident85.6Confident112 Ų11266.3 Ų66.344%0.43935%0.345SS..G310 helixtrans-57.3-29.1-176.366.9-87.9000113.1P264 E282 I283P264-Y280 VanDerWaalsContact C-CD1 3.41Å; P264-Y280 HydrophobicContact CB-CD1 4.12Å; P264-Y280 HydrophobicContact CB-CD2 4.11Å; P264-Y280 HydrophobicContact CB-CE1 3.95Å; P264-Y280 HydrophobicContact CB-CE2 3.95Å; P264-Y280 HydrophobicContact CB-CG 4.2Å; Y280-E282 PolarHBondContact O-N 3.27Å; Y280-I283 PolarHBondContact O-N 3.41Å
281S83.4Confident85.8Confident91 Ų9171.6 Ų71.664%0.63637%0.367SS*.G310 helixtrans-71.7-15176.651.20000114E279E279-S281 PolarHBondContact O-N 3.43Å
282E81.2Confident85.9Confident113 Ų11367.5 Ų67.553%0.52835%0.351SS..G310 helixtrans-98.6-8.2-179.5-56.5178.4163.500112.2V278 E279 Y280V278-E282 HydrophobicContact CG1-CB 3.82Å; E279-E282 HydrophobicContact CB-CG 4.25Å; E279-E282 WeakPolarHBondContact O-CB 3.38Å; E279-E282 PolarHBondContact O-N 2.95Å; Y280-E282 PolarHBondContact O-N 3.27Å
283I81.8Confident86Confident22 Ų2267.2 Ų67.211%0.11336%0.359CS..SBendtrans-93.2125.7-178.8-53173.2000108.9V267 V278 Y280 L287 A288 L299V267-I283 HydrophobicContact CB-CD1 4.11Å; V267-I283 HydrophobicContact CG2-CD1 3.6Å; V278-I283 HydrophobicContact CB-CG1 4.41Å; V278-I283 HydrophobicContact CG1-CD1 4.29Å; V278-I283 HydrophobicContact CG1-CG1 3.6Å; Y280-I283 PolarHBondContact O-N 3.41Å; I283-L287 HydrophobicContact CG2-CB 4.09Å; I283-L287 HydrophobicContact CG2-CD2 4.12Å; I283-L287 HydrophobicContact CG2-CG 4.02Å; I283-A288 HydrophobicContact CG2-CB 3.81Å; I283-L299 HydrophobicContact CD1-CD1 4.08Å; I283-L299 HydrophobicContact CG1-CD1 4.49Å; I283-L299 HydrophobicContact CG2-CD1 3.76Å
284S85Confident86.1Confident66 Ų6671.3 Ų71.346%0.46237%0.371SS..  trans-65.2149.5174.173.80000111.1Q286 L287 A288S284-Q286 PolarHBondContact O-N 3.43Å; S284-L287 PolarHBondContact O-N 3.36Å; S284-L287 VanDerWaalsContact O-N 3.13Å; S284-L287 VanDerWaalsContact OG-CB 3.28Å; S284-L287 WeakPolarHBondContact OG-CB 3.39Å; S284-L287 PolarHBondContact OG-N 3.02Å; S284-A288 WeakPolarHBondContact O-CB 3.24Å; S284-A288 PolarHBondContact O-N 2.78Å
285Q88.2Confident85.9Confident145 Ų14567.7 Ų67.768%0.67837%0.366SS*.Hα-helixtrans-55.5-42.4179.2-69.2-175.7-15.400112.2F262 A288 Q289F262-Q285 HydrophobicContact CE1-CB 4.05Å; F262-Q285 HydrophobicContact CE1-CG 3.95Å; Q285-A288 PolarHBondContact O-N 2.82Å; Q285-Q289 WeakPolarHBondContact O-CG 3.42Å; Q285-Q289 PolarHBondContact O-N 3.5Å; Q285-Q289 VanDerWaalsContact O-N 3.16Å; Q285-Q289 PolarHBondContact O-OE1 3.47Å
286Q86.5Confident85.5Confident105 Ų10571.1 Ų71.149%0.49138%0.376SS..Hα-helixtrans-58.2-51.4177-175.1-179.76.400111.1S284 A288 Q289 Q290S284-Q286 PolarHBondContact O-N 3.43Å; Q286-A288 VanDerWaalsContact C-N 3.32Å; Q286-A288 PolarHBondContact O-N 2.79Å; Q286-Q289 PolarHBondContact O-N 2.92Å; Q286-Q290 WeakPolarHBondContact O-CG 3.26Å; Q286-Q290 PolarHBondContact O-N 3.39Å
287L84.5Confident85.2Confident57 Ų5771.2 Ų71.230%0.29838%0.375SS..Hα-helixtrans-64.7-37.7-179.8179.559000111.8I283 S284 Q289 Q290 L299I283-L287 HydrophobicContact CG2-CB 4.09Å; I283-L287 HydrophobicContact CG2-CD2 4.12Å; I283-L287 HydrophobicContact CG2-CG 4.02Å; S284-L287 PolarHBondContact O-N 3.36Å; S284-L287 VanDerWaalsContact O-N 3.13Å; S284-L287 VanDerWaalsContact OG-CB 3.28Å; S284-L287 WeakPolarHBondContact OG-CB 3.39Å; S284-L287 PolarHBondContact OG-N 3.02Å; L287-Q289 VanDerWaalsContact C-N 3.25Å; L287-Q289 PolarHBondContact O-N 3.28Å; L287-Q290 VanDerWaalsContact CD1-OE1 3.23Å; L287-Q290 PolarHBondContact O-N 3.3Å; L287-L299 HydrophobicContact CD1-CD1 4.22Å; L287-L299 HydrophobicContact CD2-CD1 4.05Å; L287-L299 HydrophobicContact CG-CD1 3.7Å
288A84.8Confident84.7Confident5 Ų572.6 Ų72.64%0.04138%0.382CS..Hα-helixtrans-63.5-31.5179.200000113P261 F262 I283 S284 Q285 Q286P261-A288 HydrophobicContact CB-CB 4.44Å; P261-A288 WeakPolarHBondContact CB-O 3.26Å; P261-A288 WeakPolarHBondContact O-CB 3.36Å; F262-A288 HydrophobicContact CE1-CB 4.48Å; I283-A288 HydrophobicContact CG2-CB 3.81Å; S284-A288 WeakPolarHBondContact O-CB 3.24Å; S284-A288 PolarHBondContact O-N 2.78Å; Q285-A288 PolarHBondContact O-N 2.82Å; Q286-A288 VanDerWaalsContact C-N 3.32Å; Q286-A288 PolarHBondContact O-N 2.79Å
289Q90.2Very high84.6Confident101 Ų10172.5 Ų72.547%0.47238%0.38SS..Hα-helixtrans-91.6-10.1-178.8-67.5177.1-61.800114.1P261 F262 Q285 Q286 L287 K291P261-Q289 HydrophobicContact CB-CG 3.81Å; P261-Q289 HydrophobicContact CG-CG 4.13Å; F262-Q289 HydrophobicContact CE1-CG 4.21Å; F262-Q289 HydrophobicContact CE2-CG 4.27Å; F262-Q289 HydrophobicContact CZ-CG 3.65Å; Q285-Q289 WeakPolarHBondContact O-CG 3.42Å; Q285-Q289 PolarHBondContact O-N 3.5Å; Q285-Q289 VanDerWaalsContact O-N 3.16Å; Q285-Q289 PolarHBondContact O-OE1 3.47Å; Q286-Q289 PolarHBondContact O-N 2.92Å; L287-Q289 VanDerWaalsContact C-N 3.25Å; L287-Q289 PolarHBondContact O-N 3.28Å; Q289-K291 PolarHBondContact O-N 3.24Å
290Q87.1Confident84.5Confident36 Ų3671.9 Ų71.917%0.16838%0.379CS..  trans-59.3138.8-179.7-80.3179.8-12.800111.3Q286 L287 L297 L298Q286-Q290 WeakPolarHBondContact O-CG 3.26Å; Q286-Q290 PolarHBondContact O-N 3.39Å; L287-Q290 VanDerWaalsContact CD1-OE1 3.23Å; L287-Q290 PolarHBondContact O-N 3.3Å; Q290-L297 WeakPolarHBondContact O-CA 3.44Å; Q290-L298 HydrophobicContact CB-CB 4.5Å; Q290-L298 HydrophobicContact CB-CD1 3.75Å; Q290-L298 HydrophobicContact CB-CG 4.04Å; Q290-L298 PolarHBondContact O-N 2.82Å
291K85.7Confident84.8Confident133 Ų13368.4 Ų68.458%0.57837%0.367SS*.BIsolated β-bridgetrans-122.8152.3-177.9-71175.5171.7-161.60111.3Q289 G295 R296 L297Q289-K291 PolarHBondContact O-N 3.24Å; K291-G295 VanDerWaalsContact CD-O 3.3Å; K291-G295 WeakPolarHBondContact CD-O 3.49Å; K291-R296 CarbonylContact C-O 3.6Å; K291-R296 WeakPolarHBondContact CA-O 3.38Å; K291-R296 WeakPolarHBondContact CB-O 3.32Å; K291-L297 HydrophobicContact CG-CD2 4Å
292D81.7Confident85.3Confident39 Ų3964 Ų6421%0.20934%0.337CS..  trans-77177.7169.171.18.6000111.7M1 N294 G295 R296 L298M1-D292 HydrophobicContact SD-CB 3.29Å; M1-D292 WeakPolarHBondContact SD-CB 3.27Å; D292-N294 PolarHBondContact O-N 3.01Å; D292-N294 VanDerWaalsContact O-N 3.09Å; D292-N294 VanDerWaalsContact OD1-C 3.3Å; D292-N294 VanDerWaalsContact OD1-CA 3.29Å; D292-N294 WeakPolarHBondContact OD1-CA 3.36Å; D292-N294 WeakPolarHBondContact OD1-CB 3.43Å; D292-N294 PolarHBondContact OD1-N 3.15Å; D292-G295 PolarHBondContact O-N 3.46Å; D292-G295 PolarHBondContact OD1-N 2.71Å; D292-R296 PolarHBondContact N-O 3.13Å; D292-R296 PolarHBondContact OD1-N 2.62Å; D292-L298 HydrophobicContact CB-CD2 3.65Å; D292-L298 VanDerWaalsContact N-CD2 3.34Å
293S81.4Confident86.1Confident115 Ų11559.3 Ų59.380%0.80432%0.315SS*.THydrogen-bonded Turntrans-60.5-16176.559.70000114.3
294N81Confident86.7Confident129 Ų12958.8 Ų58.869%0.6931%0.313SS*.THydrogen-bonded Turntrans-97.44.3177.4-53-53.9000112D292 R296D292-N294 PolarHBondContact O-N 3.01Å; D292-N294 VanDerWaalsContact O-N 3.09Å; D292-N294 VanDerWaalsContact OD1-C 3.3Å; D292-N294 VanDerWaalsContact OD1-CA 3.29Å; D292-N294 WeakPolarHBondContact OD1-CA 3.36Å; D292-N294 WeakPolarHBondContact OD1-CB 3.43Å; D292-N294 PolarHBondContact OD1-N 3.15Å; N294-R296 VanDerWaalsContact C-N 3.3Å; N294-R296 PolarHBondContact O-N 2.89Å
295G83.9Confident87.3Confident39 Ų3956.4 Ų56.440%0.40230%0.297SS..SBendtrans78.28.3-178.600000114.9K291 D292K291-G295 VanDerWaalsContact CD-O 3.3Å; K291-G295 WeakPolarHBondContact CD-O 3.49Å; D292-G295 PolarHBondContact O-N 3.46Å; D292-G295 PolarHBondContact OD1-N 2.71Å
296R84.4Confident87.7Confident90 Ų9049.7 Ų49.734%0.3427%0.266SS..  trans-84.9147.7175.8-66.3-176.3134.8-153.9-15.7110.5E257 K291 D292 N294 L298E257-R296 IonicContact OE1-CZ 3.84Å; E257-R296 IonicContact OE1-NE 3.49Å; E257-R296 PolarHBondContact OE1-NE 3.47Å; E257-R296 IonicContact OE1-NH2 2.78Å; E257-R296 PolarHBondContact OE1-NH2 3.19Å; E257-R296 IonicContact OE2-CZ 3.06Å; E257-R296 IonicContact OE2-NH2 3.63Å; E257-R296 PolarHBondContact OE2-NH2 2.86Å; K291-R296 CarbonylContact C-O 3.6Å; K291-R296 WeakPolarHBondContact CA-O 3.38Å; K291-R296 WeakPolarHBondContact CB-O 3.32Å; D292-R296 PolarHBondContact N-O 3.13Å; D292-R296 PolarHBondContact OD1-N 2.62Å; N294-R296 VanDerWaalsContact C-N 3.3Å; N294-R296 PolarHBondContact O-N 2.89Å; R296-L298 PolarHBondContact O-N 3.46Å
297L84.4Confident88.3Confident15 Ų1544.7 Ų44.78%0.07924%0.242CC..BIsolated β-bridgetrans-62.3135.2176.9-61.8175.9000110.8R258 P261 Q290 K291 L299 S300R258-L297 HydrophobicContact CB-CD1 4.35Å; P261-L297 HydrophobicContact CG-CD1 4.07Å; P261-L297 HydrophobicContact CG-CD2 3.8Å; Q290-L297 WeakPolarHBondContact O-CA 3.44Å; K291-L297 HydrophobicContact CG-CD2 4Å; L297-L299 VanDerWaalsContact C-N 3.28Å; L297-L299 PolarHBondContact O-N 3.21Å; L297-S300 WeakPolarHBondContact O-CB 3.34Å; L297-S300 PolarHBondContact O-N 3.36Å; L297-S300 PolarHBondContact O-OG 3.2Å
298L82.9Confident89Confident43 Ų4342 Ų4223%0.22523%0.228CC..THydrogen-bonded Turntrans-62.1-42.7173.7-63-169.8000110.9M1 L3 Q290 D292 R296 S300M1-L298 HydrophobicContact CE-CD1 3.75Å; M1-L298 HydrophobicContact CE-CD2 3.23Å; M1-L298 HydrophobicContact CE-CG 4.15Å; M1-L298 HydrophobicContact SD-CD2 3.31Å; M1-L298 WeakPolarHBondContact SD-CD2 3.25Å; L3-L298 HydrophobicContact CD2-CD1 3.78Å; Q290-L298 HydrophobicContact CB-CB 4.5Å; Q290-L298 HydrophobicContact CB-CD1 3.75Å; Q290-L298 HydrophobicContact CB-CG 4.04Å; Q290-L298 PolarHBondContact O-N 2.82Å; D292-L298 HydrophobicContact CB-CD2 3.65Å; D292-L298 VanDerWaalsContact N-CD2 3.34Å; R296-L298 PolarHBondContact O-N 3.46Å; L298-S300 VanDerWaalsContact C-N 3.3Å; L298-S300 PolarHBondContact O-N 2.8Å
299L84.7Confident89.6Confident32 Ų3241.8 Ų41.817%0.16823%0.226CC..THydrogen-bonded Turntrans-94.456.7175.6-66.7-167.9000110.6R258 V267 I283 L287 L297R258-L299 WeakPolarHBondContact CD-O 3.18Å; R258-L299 PolarHBondContact NH1-O 3.28Å; V267-L299 HydrophobicContact CG1-CB 3.85Å; V267-L299 HydrophobicContact CG1-CD2 4.08Å; V267-L299 HydrophobicContact CG1-CG 4.44Å; V267-L299 HydrophobicContact CG2-CB 4.31Å; I283-L299 HydrophobicContact CD1-CD1 4.08Å; I283-L299 HydrophobicContact CG1-CD1 4.49Å; I283-L299 HydrophobicContact CG2-CD1 3.76Å; L287-L299 HydrophobicContact CD1-CD1 4.22Å; L287-L299 HydrophobicContact CD2-CD1 4.05Å; L287-L299 HydrophobicContact CG-CD1 3.7Å; L297-L299 VanDerWaalsContact C-N 3.28Å; L297-L299 PolarHBondContact O-N 3.21Å
300S87.4Confident90Very high21 Ų2137.9 Ų37.915%0.14721%0.209CC..  trans-84.9-23-175.642.30000114.6E257 R258 L297 L298 G302E257-S300 WeakPolarHBondContact CA-O 3.37Å; R258-S300 WeakPolarHBondContact CG-O 3.32Å; R258-S300 PolarHBondContact N-O 3.1Å; L297-S300 WeakPolarHBondContact O-CB 3.34Å; L297-S300 PolarHBondContact O-N 3.36Å; L297-S300 PolarHBondContact O-OG 3.2Å; L298-S300 VanDerWaalsContact C-N 3.3Å; L298-S300 PolarHBondContact O-N 2.8Å; S300-G302 PolarHBondContact O-N 2.9Å; S300-G302 VanDerWaalsContact O-N 3.09Å
301Q91.1Very high90.5Very high39 Ų3936.7 Ų36.718%0.18220%0.204CC..EExtended strand (participates in β ladder)trans-82.387.8-171.4-62.5-65.80.900112.2S255 V267 I268 E371S255-Q301 VanDerWaalsContact CB-OE1 3.25Å; S255-Q301 PolarHBondContact OG-OE1 3.22Å; V267-Q301 WeakPolarHBondContact CA-O 3.42Å; I268-Q301 HydrophobicContact CB-CB 4.22Å; I268-Q301 PolarHBondContact N-O 3.33Å; Q301-E371 PolarHBondContact NE2-OE2 3.06Å; Q301-E371 PolarHBondContact OE1-OE2 3.41Å
302G94.5Very high91.1Very high0 Ų034.1 Ų34.10%020%0.203CC..EExtended strand (participates in β ladder)trans-73.1125.7177.500000112.2S255 V256 S300 I304S255-G302 WeakPolarHBondContact CA-O 3.32Å; S255-G302 WeakPolarHBondContact CB-O 3.33Å; V256-G302 PolarHBondContact N-O 3.49Å; V256-G302 PolarHBondContact O-N 2.94Å; S300-G302 PolarHBondContact O-N 2.9Å; S300-G302 VanDerWaalsContact O-N 3.09Å; G302-I304 PolarHBondContact O-N 2.88Å
303N96Very high91.9Very high13 Ų1332.3 Ų32.37%0.0719%0.193CC..EExtended strand (participates in β ladder)trans-74.6113.4174.3179.622.2000110.9V253 I265 G266 I268 V277 A305 F358V253-N303 VanDerWaalsContact CG2-OD1 3.32Å; V253-N303 WeakPolarHBondContact CG2-OD1 3.44Å; I265-N303 VanDerWaalsContact CG1-O 3.31Å; I265-N303 WeakPolarHBondContact CG1-O 3.41Å; G266-N303 WeakPolarHBondContact O-CB 3.31Å; G266-N303 PolarHBondContact O-N 3.05Å; I268-N303 HydrophobicContact CD1-CB 4.25Å; I268-N303 HydrophobicContact CG1-CB 3.94Å; V277-N303 HydrophobicContact CG1-CB 4.15Å; V277-N303 HydrophobicContact CG2-CB 4.22Å; N303-A305 VanDerWaalsContact C-N 3.32Å; N303-A305 PolarHBondContact OD1-N 2.73Å; N303-F358 VanDerWaalsContact ND2-CD1 3.32Å; N303-F358 WeakPolarHBondContact ND2-CD1 3.5Å
304I96.3Very high92.7Very high12 Ų1226.9 Ų26.96%0.06216%0.155CC..EExtended strand (participates in β ladder)trans-93.313.1177.963.1164.9000113.7K254 V256 I265 G302 N306 V372 F378K254-I304 HydrophobicContact CB-CD1 3.92Å; K254-I304 HydrophobicContact CB-CG1 4.05Å; K254-I304 WeakPolarHBondContact O-CG1 3.19Å; V256-I304 HydrophobicContact CB-CG2 4.2Å; V256-I304 HydrophobicContact CG1-CD1 4.29Å; V256-I304 HydrophobicContact CG1-CG2 3.78Å; V256-I304 HydrophobicContact CG2-CG2 3.48Å; V256-I304 VanDerWaalsContact CG2-CG2 3.48Å; I265-I304 HydrophobicContact CD1-CG2 4Å; G302-I304 PolarHBondContact O-N 2.88Å; I304-N306 HydrophobicContact CD1-CB 4.18Å; I304-N306 HydrophobicContact CG1-CB 4.02Å; I304-N306 PolarHBondContact O-N 3.48Å; I304-V372 HydrophobicContact CD1-CG2 4.23Å; I304-F378 HydrophobicContact CB-CD2 3.62Å; I304-F378 HydrophobicContact CB-CE2 3.73Å; I304-F378 HydrophobicContact CB-CG 4.16Å; I304-F378 HydrophobicContact CB-CZ 4.34Å; I304-F378 HydrophobicContact CD1-CB 4.36Å; I304-F378 HydrophobicContact CD1-CD2 4.4Å; I304-F378 HydrophobicContact CG2-CB 4.2Å; I304-F378 HydrophobicContact CG2-CD1 3.74Å; I304-F378 HydrophobicContact CG2-CD2 3.48Å; I304-F378 VanDerWaalsContact CG2-CD2 3.48Å; I304-F378 HydrophobicContact CG2-CE1 3.87Å; I304-F378 HydrophobicContact CG2-CE2 3.63Å; I304-F378 HydrophobicContact CG2-CG 3.54Å; I304-F378 HydrophobicContact CG2-CZ 3.82Å
305A95.8Very high93.4Very high16 Ų1622.9 Ų22.913%0.13213%0.132CC..EExtended strand (participates in β ladder)trans54.838.2179.800000113.9N303 H307N303-A305 VanDerWaalsContact C-N 3.32Å; N303-A305 PolarHBondContact OD1-N 2.73Å; A305-H307 VanDerWaalsContact C-CE1 3.4Å; A305-H307 WeakPolarHBondContact CA-CE1 3.32Å
306N97.9Very high93.9Very high4 Ų423.7 Ų23.72%0.02113%0.126CC..EExtended strand (participates in β ladder)trans-117.6110.1175.6-170.4-61.4000108H224 V253 K254 I304H224-N306 PolarHBondContact CD2-OD1 3.41Å; H224-N306 PolarHBondContact NE2-ND2 3.45Å; H224-N306 PolarHBondContact NE2-OD1 2.76Å; V253-N306 CarbonylContact C-O 3.49Å; V253-N306 WeakPolarHBondContact CA-O 3.41Å; K254-N306 HydrophobicContact CB-CB 4.16Å; K254-N306 HydrophobicContact CD-CB 4.32Å; K254-N306 WeakPolarHBondContact CD-OD1 3.33Å; K254-N306 HydrophobicContact CG-CB 4.43Å; K254-N306 PolarHBondContact N-O 3.47Å; I304-N306 HydrophobicContact CD1-CB 4.18Å; I304-N306 HydrophobicContact CG1-CB 4.02Å; I304-N306 PolarHBondContact O-N 3.48Å
307H98.4Very high94.4Very high0 Ų019.6 Ų19.60%011%0.11CC..EExtended strand (participates in β ladder)trans-125.3151.5-167.3-46.795.6000110.7H224 V225 A252 A305 F309 I357 F361H224-H307 CarbonylContact C-O 3.59Å; H224-H307 VanDerWaalsContact CA-O 3.31Å; H224-H307 WeakPolarHBondContact CA-O 3.24Å; H224-H307 PolarHBondContact CD2-O 2.85Å; V225-H307 HydrophobicContact CB-CB 4.49Å; V225-H307 PolarHBondContact N-O 3.28Å; V225-H307 PolarHBondContact O-N 2.87Å; A252-H307 CarbonylContact O-C 3.41Å; A252-H307 WeakPolarHBondContact O-CA 3.29Å; A305-H307 VanDerWaalsContact C-CE1 3.4Å; A305-H307 WeakPolarHBondContact CA-CE1 3.32Å; H307-F309 HydrophobicContact CB-CD2 4.36Å; H307-F309 HydrophobicContact CB-CE1 4.38Å; H307-F309 HydrophobicContact CB-CE2 3.69Å; H307-F309 HydrophobicContact CB-CZ 3.7Å; H307-I357 VanDerWaalsContact CE1-CG2 3.47Å; H307-I357 WeakPolarHBondContact CE1-CG2 3.4Å; H307-F361 AromaticContact CD2-CE1 3.65Å; H307-F361 AromaticContact CD2-CZ 3.47Å; H307-F361 VanDerWaalsContact CD2-CZ 3.47Å; H307-F361 WeakPolarHBondContact CD2-CZ 3.4Å; H307-F361 AromaticContact NE2-CZ 3.57Å
308L98.7Very high94.8Very high0 Ų019.2 Ų19.20%011%0.109CC..EExtended strand (participates in β ladder)trans-120.8125.1164.3-176.3152.1000108.5Y222 V223 F240 I241 C244 C251 A252Y222-L308 HydrophobicContact CD1-CD2 4.2Å; V223-L308 WeakPolarHBondContact O-CA 3.47Å; F240-L308 HydrophobicContact CD1-CB 4.07Å; F240-L308 HydrophobicContact CD1-CD1 4.46Å; F240-L308 HydrophobicContact CE1-CB 3.49Å; F240-L308 VanDerWaalsContact CE1-CB 3.49Å; F240-L308 HydrophobicContact CE2-CB 4.42Å; F240-L308 HydrophobicContact CZ-CB 3.69Å; I241-L308 HydrophobicContact CB-CD1 4.11Å; I241-L308 HydrophobicContact CG1-CD1 3.62Å; C244-L308 HydrophobicContact CB-CD1 4.01Å; C244-L308 HydrophobicContact CB-CD2 3.63Å; C244-L308 HydrophobicContact CB-CG 4.35Å; C251-L308 CarbonylContact C-O 3.52Å; C251-L308 WeakPolarHBondContact CA-O 3.29Å; A252-L308 PolarHBondContact N-O 3.09Å; A252-L308 PolarHBondContact O-N 2.79Å
309F98.6Very high94.6Very high0 Ų022 Ų220%012%0.12CC..EExtended strand (participates in β ladder)trans-114.9142172.1-55.1-69.2000109.6Y203 V223 V225 C251 H307 F313 L314 I357 V360Y203-F309 VanDerWaalsContact OH-CZ 3.3Å; Y203-F309 WeakPolarHBondContact OH-CZ 3.41Å; V223-F309 PolarHBondContact N-O 2.86Å; V223-F309 PolarHBondContact O-N 2.87Å; V225-F309 HydrophobicContact CB-CD2 4.36Å; V225-F309 HydrophobicContact CB-CE2 4.09Å; V225-F309 HydrophobicContact CG2-CD2 3.52Å; V225-F309 HydrophobicContact CG2-CE2 3.69Å; C251-F309 HydrophobicContact CB-CD1 4.06Å; C251-F309 HydrophobicContact CB-CE1 4.34Å; C251-F309 WeakPolarHBondContact SG-CE1 3.47Å; H307-F309 HydrophobicContact CB-CD2 4.36Å; H307-F309 HydrophobicContact CB-CE1 4.38Å; H307-F309 HydrophobicContact CB-CE2 3.69Å; H307-F309 HydrophobicContact CB-CZ 3.7Å; F309-F313 HydrophobicContact CB-CD1 4.11Å; F309-F313 AromaticContact CD1-CD1 3.49Å; F309-F313 HydrophobicContact CD1-CD1 3.49Å; F309-F313 VanDerWaalsContact CD1-CD1 3.49Å; F309-F313 AromaticContact CD1-CE1 3.47Å; F309-F313 HydrophobicContact CD1-CE1 3.47Å; F309-F313 VanDerWaalsContact CD1-CE1 3.47Å; F309-F313 HydrophobicContact CE1-CD1 4.27Å; F309-F313 AromaticContact CE1-CE1 3.78Å; F309-F313 HydrophobicContact CE1-CE1 3.78Å; F309-F313 HydrophobicContact CG-CD1 4.11Å; F309-F313 HydrophobicContact CG-CE1 4.42Å; F309-L314 HydrophobicContact CB-CD1 4.12Å; F309-L314 HydrophobicContact CB-CD2 3.74Å; F309-L314 HydrophobicContact CB-CG 3.63Å; F309-L314 HydrophobicContact CD2-CD2 3.68Å; F309-L314 HydrophobicContact CD2-CG 4.41Å; F309-L314 HydrophobicContact CE2-CD2 4.42Å; F309-L314 HydrophobicContact CG-CD2 3.75Å; F309-L314 HydrophobicContact CG-CG 4.23Å; F309-I357 HydrophobicContact CE2-CD1 4.41Å; F309-I357 HydrophobicContact CZ-CG1 4.48Å; F309-V360 HydrophobicContact CE1-CG2 3.87Å; F309-V360 HydrophobicContact CZ-CG2 4.16Å
310T98.7Very high94.5Very high20 Ų2025.8 Ų25.812%0.12314%0.14CC..EExtended strand (participates in β ladder)trans-69.2147.2161.555.90000109.6R221 Y222 A249 D250 S312 F313 L314R221-T310 CarbonylContact O-C 3.55Å; R221-T310 VanDerWaalsContact O-CA 3.3Å; R221-T310 WeakPolarHBondContact O-CA 3.2Å; Y222-T310 HydrophobicContact CD1-CG2 4.45Å; Y222-T310 HydrophobicContact CE1-CG2 4.45Å; A249-T310 WeakPolarHBondContact O-CG2 3.4Å; D250-T310 PolarHBondContact O-N 3.36Å; D250-T310 PolarHBondContact O-OG1 2.95Å; T310-S312 PolarHBondContact O-N 3.47Å; T310-S312 PolarHBondContact OG1-OG 3.16Å; T310-F313 WeakPolarHBondContact O-CB 3.5Å; T310-F313 PolarHBondContact O-N 2.96Å; T310-F313 VanDerWaalsContact O-N 3.1Å; T310-F313 WeakPolarHBondContact OG1-CB 3.33Å; T310-F313 PolarHBondContact OG1-N 2.94Å; T310-L314 PolarHBondContact O-N 2.9Å
311L98.4Very high93.7Very high11 Ų1130 Ų306%0.05816%0.161CC..Hα-helixtrans-59-37.5176.3-179.561.6000111.2L212 L215 I220 R221 F313 L314 Q315L212-L311 HydrophobicContact CD2-CD1 4.02Å; L215-L311 HydrophobicContact CB-CD1 3.96Å; L215-L311 HydrophobicContact CB-CD2 4.28Å; L215-L311 HydrophobicContact CD1-CD1 4.24Å; I220-L311 WeakPolarHBondContact O-CD2 3.29Å; R221-L311 PolarHBondContact O-N 2.78Å; L311-F313 PolarHBondContact O-N 3.39Å; L311-L314 PolarHBondContact O-N 3.32Å; L311-Q315 HydrophobicContact CD1-CG 4.41Å; L311-Q315 HydrophobicContact CG-CG 4.42Å; L311-Q315 WeakPolarHBondContact O-CB 3.35Å; L311-Q315 VanDerWaalsContact O-CG 3.29Å; L311-Q315 WeakPolarHBondContact O-CG 3.31Å; L311-Q315 PolarHBondContact O-N 3.46Å
312S97.6Very high93.2Very high78 Ų7829.4 Ų29.455%0.54516%0.161SC..Hα-helixtrans-62.3-39.8175.450.60000112.5T310 Q315 Q316T310-S312 PolarHBondContact O-N 3.47Å; T310-S312 PolarHBondContact OG1-OG 3.16Å; S312-Q315 PolarHBondContact O-N 3.05Å; S312-Q316 WeakPolarHBondContact O-CB 3.47Å; S312-Q316 PolarHBondContact O-N 3.41Å
313F97.9Very high92.5Very high2 Ų237.6 Ų37.61%0.00920%0.199CC..Hα-helixtrans-63.8-46.7173.5178.8-98.3000111.7D250 C251 F309 T310 L311 Q315 Q316 V317 V360D250-F313 HydrophobicContact CB-CB 4.22Å; D250-F313 HydrophobicContact CB-CD2 4.39Å; D250-F313 WeakPolarHBondContact O-CB 3.44Å; C251-F313 HydrophobicContact CB-CD1 4.31Å; C251-F313 HydrophobicContact CB-CE1 4.05Å; C251-F313 HydrophobicContact CB-CE2 4.39Å; C251-F313 HydrophobicContact CB-CZ 4.09Å; F309-F313 HydrophobicContact CB-CD1 4.11Å; F309-F313 AromaticContact CD1-CD1 3.49Å; F309-F313 HydrophobicContact CD1-CD1 3.49Å; F309-F313 VanDerWaalsContact CD1-CD1 3.49Å; F309-F313 AromaticContact CD1-CE1 3.47Å; F309-F313 HydrophobicContact CD1-CE1 3.47Å; F309-F313 VanDerWaalsContact CD1-CE1 3.47Å; F309-F313 HydrophobicContact CE1-CD1 4.27Å; F309-F313 AromaticContact CE1-CE1 3.78Å; F309-F313 HydrophobicContact CE1-CE1 3.78Å; F309-F313 HydrophobicContact CG-CD1 4.11Å; F309-F313 HydrophobicContact CG-CE1 4.42Å; T310-F313 WeakPolarHBondContact O-CB 3.5Å; T310-F313 PolarHBondContact O-N 2.96Å; T310-F313 VanDerWaalsContact O-N 3.1Å; T310-F313 WeakPolarHBondContact OG1-CB 3.33Å; T310-F313 PolarHBondContact OG1-N 2.94Å; L311-F313 PolarHBondContact O-N 3.39Å; F313-Q315 VanDerWaalsContact C-N 3.31Å; F313-Q315 PolarHBondContact O-N 2.97Å; F313-Q316 WeakPolarHBondContact O-CB 3.4Å; F313-Q316 PolarHBondContact O-N 3.09Å; F313-Q316 VanDerWaalsContact O-N 3.11Å; F313-V317 HydrophobicContact CD1-CG1 4.46Å; F313-V317 HydrophobicContact CD2-CG1 4.37Å; F313-V317 HydrophobicContact CE1-CG1 3.96Å; F313-V317 HydrophobicContact CE1-CG2 4.42Å; F313-V317 HydrophobicContact CE2-CG1 3.82Å; F313-V317 HydrophobicContact CZ-CG1 3.61Å; F313-V317 WeakPolarHBondContact O-CG2 3.45Å; F313-V317 PolarHBondContact O-N 3.44Å; F313-V360 HydrophobicContact CE1-CB 4.3Å; F313-V360 HydrophobicContact CE1-CG2 3.92Å; F313-V360 HydrophobicContact CZ-CB 4.14Å; F313-V360 HydrophobicContact CZ-CG2 4.09Å
314L97.8Very high92.3Very high0 Ų037.8 Ų37.80%020%0.2CC..Hα-helixtrans-58.8-43.5176-70.6179.2000111.9I81 Y203 L206 L212 V223 F309 T310 L311 Q316 V317 A318I81-L314 HydrophobicContact CD1-CD1 4.48Å; Y203-L314 HydrophobicContact CD1-CD2 4.02Å; Y203-L314 HydrophobicContact CE1-CD2 3.74Å; L206-L314 HydrophobicContact CD1-CD1 4.31Å; L206-L314 HydrophobicContact CD1-CD2 4.35Å; L212-L314 HydrophobicContact CD2-CB 3.88Å; V223-L314 HydrophobicContact CB-CD1 3.8Å; V223-L314 HydrophobicContact CG1-CD1 3.93Å; V223-L314 HydrophobicContact CG2-CD1 3.85Å; F309-L314 HydrophobicContact CB-CD1 4.12Å; F309-L314 HydrophobicContact CB-CD2 3.74Å; F309-L314 HydrophobicContact CB-CG 3.63Å; F309-L314 HydrophobicContact CD2-CD2 3.68Å; F309-L314 HydrophobicContact CD2-CG 4.41Å; F309-L314 HydrophobicContact CE2-CD2 4.42Å; F309-L314 HydrophobicContact CG-CD2 3.75Å; F309-L314 HydrophobicContact CG-CG 4.23Å; T310-L314 PolarHBondContact O-N 2.9Å; L311-L314 PolarHBondContact O-N 3.32Å; L314-Q316 VanDerWaalsContact C-N 3.35Å; L314-V317 WeakPolarHBondContact O-CG2 3.21Å; L314-V317 PolarHBondContact O-N 2.78Å; L314-A318 WeakPolarHBondContact O-CB 3.31Å; L314-A318 PolarHBondContact O-N 2.88Å
315Q96.5Very high92.1Very high45 Ų4540.5 Ų40.521%0.2122%0.218CC..Hα-helixtrans-62.3-41.7174.7-73.2173.8-22.800111.6L212 L311 S312 F313 K319L212-Q315 HydrophobicContact CB-CG 4.45Å; L212-Q315 HydrophobicContact CD1-CG 4.37Å; L311-Q315 HydrophobicContact CD1-CG 4.41Å; L311-Q315 HydrophobicContact CG-CG 4.42Å; L311-Q315 WeakPolarHBondContact O-CB 3.35Å; L311-Q315 VanDerWaalsContact O-CG 3.29Å; L311-Q315 WeakPolarHBondContact O-CG 3.31Å; L311-Q315 PolarHBondContact O-N 3.46Å; S312-Q315 PolarHBondContact O-N 3.05Å; F313-Q315 VanDerWaalsContact C-N 3.31Å; F313-Q315 PolarHBondContact O-N 2.97Å; Q315-K319 HydrophobicContact CB-CD 4.45Å; Q315-K319 WeakPolarHBondContact O-CA 3.4Å; Q315-K319 WeakPolarHBondContact O-CB 3.49Å; Q315-K319 VanDerWaalsContact O-CG 3.25Å; Q315-K319 WeakPolarHBondContact O-CG 3.28Å; Q315-K319 PolarHBondContact O-N 2.86Å
316Q95.1Very high91.8Very high57 Ų5744.5 Ų44.527%0.26623%0.231SC..Hα-helixtrans-60.5-52.6176.9-175.6-169.5-54.900111.2S312 F313 L314 N320S312-Q316 WeakPolarHBondContact O-CB 3.47Å; S312-Q316 PolarHBondContact O-N 3.41Å; F313-Q316 WeakPolarHBondContact O-CB 3.4Å; F313-Q316 PolarHBondContact O-N 3.09Å; F313-Q316 VanDerWaalsContact O-N 3.11Å; L314-Q316 VanDerWaalsContact C-N 3.35Å; Q316-N320 WeakPolarHBondContact O-CB 3.18Å; Q316-N320 PolarHBondContact O-N 3.12Å; Q316-N320 VanDerWaalsContact O-N 3.1Å; Q316-N320 PolarHBondContact O-ND2 3.45Å
317V95Very high91.4Very high4 Ų446.1 Ų46.12%0.02424%0.238CC..Hα-helixtrans-71.7-33.6-174.9-59.70000112.7Y203 F313 L314 C322 V360 Y363Y203-V317 HydrophobicContact CD1-CG2 3.55Å; Y203-V317 HydrophobicContact CE1-CG2 3.98Å; Y203-V317 HydrophobicContact CG-CG2 4.2Å; F313-V317 HydrophobicContact CD1-CG1 4.46Å; F313-V317 HydrophobicContact CD2-CG1 4.37Å; F313-V317 HydrophobicContact CE1-CG1 3.96Å; F313-V317 HydrophobicContact CE1-CG2 4.42Å; F313-V317 HydrophobicContact CE2-CG1 3.82Å; F313-V317 HydrophobicContact CZ-CG1 3.61Å; F313-V317 WeakPolarHBondContact O-CG2 3.45Å; F313-V317 PolarHBondContact O-N 3.44Å; L314-V317 WeakPolarHBondContact O-CG2 3.21Å; L314-V317 PolarHBondContact O-N 2.78Å; V317-C322 HydrophobicContact CB-CB 4.46Å; V317-C322 WeakPolarHBondContact O-CB 3.31Å; V317-C322 PolarHBondContact O-N 2.96Å; V317-V360 HydrophobicContact CB-CG1 4.32Å; V317-V360 HydrophobicContact CG1-CB 4.42Å; V317-V360 HydrophobicContact CG1-CG1 4.46Å; V317-V360 HydrophobicContact CG2-CG1 4.27Å; V317-Y363 HydrophobicContact CG1-CG 4.5Å
318A92.6Very high91Very high6 Ų652.1 Ų52.15%0.0527%0.268CS..Hα-helixtrans-79.8-40.8178.500000112.7Y203 K207 L212 L314Y203-A318 WeakPolarHBondContact O-CB 3.32Å; K207-A318 HydrophobicContact CB-CB 4.17Å; K207-A318 WeakPolarHBondContact CD-O 3.48Å; L212-A318 HydrophobicContact CD1-CB 3.69Å; L314-A318 WeakPolarHBondContact O-CB 3.31Å; L314-A318 PolarHBondContact O-N 2.88Å
319K78.8Confident90.4Very high102 Ų10253.2 Ų53.244%0.44328%0.277SS..Hα-helixtrans-79-32.3-176.5-65.6-176.8175.9-1750113D213 Q315 D321D213-K319 IonicContact OD1-NZ 3.84Å; Q315-K319 HydrophobicContact CB-CD 4.45Å; Q315-K319 WeakPolarHBondContact O-CA 3.4Å; Q315-K319 WeakPolarHBondContact O-CB 3.49Å; Q315-K319 VanDerWaalsContact O-CG 3.25Å; Q315-K319 WeakPolarHBondContact O-CG 3.28Å; Q315-K319 PolarHBondContact O-N 2.86Å; K319-D321 PolarHBondContact O-N 2.91Å
320N80.8Confident90.1Very high112 Ų11261.8 Ų61.860%0.59931%0.309SS*.THydrogen-bonded Turntrans-80.910.1178.3-62.7-13000113.4Q316 C322Q316-N320 WeakPolarHBondContact O-CB 3.18Å; Q316-N320 PolarHBondContact O-N 3.12Å; Q316-N320 VanDerWaalsContact O-N 3.1Å; Q316-N320 PolarHBondContact O-ND2 3.45Å; N320-C322 PolarHBondContact O-N 3.46Å; N320-C322 VanDerWaalsContact O-N 3.14Å
321D71.9Confident89.7Confident108 Ų10864.5 Ų64.558%0.57832%0.319SS*.THydrogen-bonded Turntrans47.244.4-178.7-62.7-41.9000112K207 K319 Q323K207-D321 IonicContact NZ-OD1 3.77Å; K207-D321 PolarHBondContact NZ-OD1 2.87Å; K207-D321 IonicContact NZ-OD2 2.92Å; K207-D321 PolarHBondContact NZ-OD2 3.18Å; K319-D321 PolarHBondContact O-N 2.91Å; D321-Q323 PolarHBondContact O-N 3.1Å
322C79.5Confident89.5Confident27 Ų2770.1 Ų70.118%0.18234%0.343CS..  trans-55.2113.4177.5-72.70000108.9V317 N320 L324 Y363V317-C322 HydrophobicContact CB-CB 4.46Å; V317-C322 WeakPolarHBondContact O-CB 3.31Å; V317-C322 PolarHBondContact O-N 2.96Å; N320-C322 PolarHBondContact O-N 3.46Å; N320-C322 VanDerWaalsContact O-N 3.14Å; C322-L324 PolarHBondContact O-N 3.41Å; C322-L324 VanDerWaalsContact O-N 3.11Å; C322-Y363 HydrophobicContact CB-CD1 4.36Å; C322-Y363 HydrophobicContact CB-CE1 3.89Å; C322-Y363 HydrophobicContact CB-CE2 4.13Å; C322-Y363 VanDerWaalsContact SG-CE1 3.55Å
323Q80.9Confident89.3Confident173 Ų17366.6 Ų66.681%0.80832%0.318SS*.  trans-76.2107.3-177.5-62.6-140.7-10.200109.4D321 Y363D321-Q323 PolarHBondContact O-N 3.1Å; Q323-Y363 PolarHBondContact O-OH 2.66Å
324L91.5Very high89.1Confident17 Ų1769.1 Ų69.19%0.08934%0.335CS..PPolyproline II helixtrans-81.3139.3170-57-172.8000109.3Y203 C322 K355 D359 V360 Y363Y203-L324 HydrophobicContact CD2-CD1 3.53Å; Y203-L324 HydrophobicContact CE2-CD1 3.76Å; C322-L324 PolarHBondContact O-N 3.41Å; C322-L324 VanDerWaalsContact O-N 3.11Å; L324-K355 HydrophobicContact CB-CD 4.25Å; L324-K355 HydrophobicContact CB-CG 4.29Å; L324-D359 HydrophobicContact CB-CB 4.33Å; L324-D359 HydrophobicContact CD1-CB 4.43Å; L324-D359 HydrophobicContact CD2-CB 3.95Å; L324-D359 HydrophobicContact CG-CB 4.46Å; L324-V360 HydrophobicContact CD1-CG1 3.92Å; L324-V360 HydrophobicContact CD2-CG1 3.81Å; L324-V360 HydrophobicContact CG-CG1 4.44Å; L324-Y363 HydrophobicContact CD2-CE2 4.04Å
325P91Very high89Confident69 Ų6972.2 Ų72.245%0.44835%0.348SS..PPolyproline II helixtrans-63.5149.3177.629.2-34.6000110.7D359P325-D359 HydrophobicContact CG-CB 4.33Å
326Y90Very high88.9Confident99 Ų9971.9 Ų71.939%0.38835%0.348SS..PPolyproline II helixtrans-88.8130.3166-74-78000109.7M175 L353 K355M175-Y326 HydrophobicContact CE-CE1 3.9Å; M175-Y326 HydrophobicContact CG-CE1 3.99Å; M175-Y326 HydrophobicContact SD-CE1 4.01Å; Y326-L353 HydrophobicContact CD1-CB 3.74Å; Y326-L353 HydrophobicContact CE1-CB 4.4Å; Y326-L353 HydrophobicContact CG-CB 4.29Å; Y326-K355 HydrophobicContact CD1-CG 4.06Å; Y326-K355 HydrophobicContact CE1-CD 4.35Å; Y326-K355 HydrophobicContact CE1-CG 4.02Å; Y326-K355 VanDerWaalsContact CZ-CE 3.5Å; Y326-K355 WeakPolarHBondContact OH-CE 3.19Å
327H89.7Confident88.7Confident39 Ų3970.3 Ų70.318%0.18134%0.343CS..EExtended strand (participates in β ladder)trans-97.6129.6172.8-59.4-89.9000109.2E354 F356 D359H327-E354 WeakPolarHBondContact CB-O 3.14Å; H327-E354 PolarHBondContact CD2-O 2.64Å; H327-E354 PolarHBondContact N-O 3.18Å; H327-E354 PolarHBondContact O-N 2.97Å; H327-F356 HydrophobicContact CB-CD2 4.34Å; H327-F356 HydrophobicContact CB-CE2 3.71Å; H327-F356 HydrophobicContact CB-CZ 3.94Å; H327-F356 AromaticContact CD2-CD2 3.24Å; H327-F356 WeakPolarHBondContact CD2-CD2 3.39Å; H327-F356 AromaticContact CD2-CE2 3.53Å; H327-F356 AromaticContact CD2-CG 3.83Å; H327-F356 AromaticContact CE1-CD2 3.58Å; H327-F356 AromaticContact CE1-CE2 3.83Å; H327-F356 AromaticContact CG-CD2 3.54Å; H327-F356 AromaticContact CG-CE2 3.3Å; H327-F356 AromaticContact ND1-CD2 3.78Å; H327-F356 AromaticContact ND1-CE2 3.55Å; H327-F356 AromaticContact NE2-CD2 3.26Å; H327-F356 VanDerWaalsContact NE2-CD2 3.26Å; H327-F356 WeakPolarHBondContact NE2-CD2 3.44Å; H327-F356 AromaticContact NE2-CE2 3.84Å; H327-D359 IonicContact CD2-OD2 3.9Å; H327-D359 PolarHBondContact CD2-OD2 2.85Å; H327-D359 IonicContact CE1-OD2 3.42Å; H327-D359 IonicContact NE2-OD1 3.35Å; H327-D359 IonicContact NE2-OD2 2.65Å; H327-D359 PolarHBondContact NE2-OD2 3.49Å
328M89.3Confident88.4Confident126 Ų12677.6 Ų77.662%0.62139%0.388SS*.EExtended strand (participates in β ladder)trans-91118.2-178-76.2170.64400111.2F351 L353M328-F351 HydrophobicContact CB-CD1 4.29Å; M328-F351 HydrophobicContact CE-CD1 3.54Å; M328-F351 HydrophobicContact CE-CD2 4.47Å; M328-F351 HydrophobicContact CE-CE1 3.48Å; M328-F351 VanDerWaalsContact CE-CE1 3.48Å; M328-F351 HydrophobicContact CE-CE2 4.42Å; M328-F351 HydrophobicContact CE-CG 4.05Å; M328-F351 HydrophobicContact CE-CZ 3.96Å; M328-L353 HydrophobicContact CB-CD2 4.5Å; M328-L353 HydrophobicContact CG-CD2 3.53Å
329A87.1Confident88.4Confident23 Ų2381.4 Ų81.419%0.1941%0.407CS..EExtended strand (participates in β ladder)trans-108.7115.5175.100000111K331 F351 K352A329-K331 PolarHBondContact O-N 3.47Å; A329-F351 WeakPolarHBondContact O-CA 3.43Å; A329-K352 PolarHBondContact N-O 3Å; A329-K352 PolarHBondContact O-N 3.48Å
330R90.9Very high88.9Confident179 Ų17977.6 Ų77.668%0.67540%0.397SS*.EExtended strand (participates in β ladder)trans-68.4126.5172.5-79.7-173176.5171.73.9110.8A348 G350 F351R330-A348 HydrophobicContact CB-CB 4.37Å; R330-G350 WeakPolarHBondContact CA-O 3.34Å; R330-F351 HydrophobicContact CG-CD1 3.49Å; R330-F351 VanDerWaalsContact CG-CD1 3.49Å; R330-F351 HydrophobicContact CG-CE1 3.23Å; R330-F351 HydrophobicContact CG-CZ 4.12Å; R330-F351 VanDerWaalsContact NE-CE1 3.26Å
331K91.2Very high89.5Confident78 Ų7880.3 Ų80.334%0.33940%0.399SS..EExtended strand (participates in β ladder)trans-141162.1-177.2-60.9-67.6178.2-177.60111.6A329 I333 A348 N349 G350 K352A329-K331 PolarHBondContact O-N 3.47Å; K331-I333 HydrophobicContact CB-CD1 4.33Å; K331-I333 HydrophobicContact CB-CG1 4.03Å; K331-A348 VanDerWaalsContact O-CA 3.29Å; K331-A348 WeakPolarHBondContact O-CA 3.27Å; K331-N349 PolarHBondContact O-N 3.08Å; K331-N349 PolarHBondContact O-OD1 3.41Å; K331-G350 PolarHBondContact N-O 2.81Å; K331-G350 PolarHBondContact O-N 3.02Å; K331-K352 HydrophobicContact CB-CG 4.49Å; K331-K352 HydrophobicContact CG-CD 4.08Å; K331-K352 HydrophobicContact CG-CG 4.14Å
332K93.5Very high90.6Very high129 Ų12980.4 Ų80.456%0.56140%0.399SS*.  trans-79.8108.1162.9-61.2-179.5-175.2-165.40106.9P345 D346K332-P345 HydrophobicContact CB-CG 4.05Å; K332-P345 WeakPolarHBondContact CD-O 3.39Å; K332-D346 WeakPolarHBondContact CE-O 3.28Å; K332-D346 PolarHBondContact NZ-O 3.08Å
333I93.2Very high91.3Very high4 Ų481.6 Ų81.62%0.02141%0.405CS..  trans-113.7118.2-176.7-63.6152.7000107.1C177 I185 A193 K331 F335 P345 N349 K352C177-I333 HydrophobicContact CB-CD1 4.05Å; C177-I333 HydrophobicContact CB-CG2 3.91Å; I185-I333 HydrophobicContact CD1-CB 4.03Å; I185-I333 HydrophobicContact CD1-CD1 4.09Å; I185-I333 HydrophobicContact CD1-CG2 3.84Å; I185-I333 HydrophobicContact CG2-CG2 4.21Å; A193-I333 HydrophobicContact CB-CG2 3.98Å; K331-I333 HydrophobicContact CB-CD1 4.33Å; K331-I333 HydrophobicContact CB-CG1 4.03Å; I333-F335 PolarHBondContact O-N 3.04Å; I333-P345 WeakPolarHBondContact O-CG 3.43Å; I333-N349 PolarHBondContact N-OD1 3.47Å; I333-N349 PolarHBondContact O-ND2 3.26Å; I333-N349 PolarHBondContact O-OD1 2.78Å; I333-K352 HydrophobicContact CD1-CG 4.22Å; I333-K352 HydrophobicContact CG1-CG 4.48Å
334P94.7Very high92Very high54 Ų5478.4 Ų78.435%0.35140%0.398SS..  trans-52.6137.5172.9-25.635000110.9L342 V343P334-L342 HydrophobicContact CB-CD1 3.77Å; P334-V343 VanDerWaalsContact CA-O 3.31Å; P334-V343 WeakPolarHBondContact CA-O 3.1Å
335F95.1Very high92Very high65 Ų6578.3 Ų78.329%0.28540%0.398SS..EExtended strand (participates in β ladder)trans-142.3156.2-175.671.5-77.8000111.5I185 L186 I333 V343 P345 N349I185-F335 HydrophobicContact CG2-CB 3.48Å; I185-F335 VanDerWaalsContact CG2-CB 3.48Å; L186-F335 CarbonylContact O-C 3.39Å; L186-F335 WeakPolarHBondContact O-CA 3.44Å; I333-F335 PolarHBondContact O-N 3.04Å; F335-V343 HydrophobicContact CD1-CB 4.28Å; F335-V343 HydrophobicContact CE1-CB 3.82Å; F335-V343 HydrophobicContact CE1-CG1 3.7Å; F335-V343 HydrophobicContact CE2-CB 4.45Å; F335-V343 HydrophobicContact CZ-CB 3.92Å; F335-V343 HydrophobicContact CZ-CG1 3.86Å; F335-V343 PolarHBondContact N-O 3.17Å; F335-V343 PolarHBondContact O-N 3.03Å; F335-P345 HydrophobicContact CD1-CG 4.46Å; F335-P345 HydrophobicContact CE1-CB 4.09Å; F335-P345 HydrophobicContact CE1-CG 4.49Å; F335-N349 WeakPolarHBondContact CD1-ND2 3.49Å
336L94.3Very high92.1Very high39 Ų3981.9 Ų81.920%0.20441%0.413CS..EExtended strand (participates in β ladder)trans-82.4120.4174.4-159.975.3000109.4L186 R189 G340 R341L186-L336 HydrophobicContact CB-CB 4.11Å; L186-L336 PolarHBondContact O-N 3.42Å; R189-L336 HydrophobicContact CG-CD2 3.96Å; L336-G340 WeakPolarHBondContact CD1-O 3.45Å; L336-R341 WeakPolarHBondContact CA-O 3.29Å
337S92.2Very high92.3Very high24 Ų2485.4 Ų85.417%0.16843%0.431CS..  trans-68.7167.8172.352.40000111.8D339 G340 R341S337-D339 VanDerWaalsContact CB-OD1 3.24Å; S337-D339 WeakPolarHBondContact CB-OD1 3.48Å; S337-D339 PolarHBondContact O-N 2.94Å; S337-D339 PolarHBondContact OG-OD1 3.01Å; S337-G340 WeakPolarHBondContact O-CA 3.14Å; S337-G340 PolarHBondContact O-N 3.27Å; S337-R341 PolarHBondContact N-O 3.45Å; S337-R341 WeakPolarHBondContact OG-CB 3.31Å; S337-R341 PolarHBondContact OG-N 2.7Å; S337-R341 VanDerWaalsContact OG-N 3.16Å; S337-R341 PolarHBondContact OG-O 2.81Å
338T88.4Confident92.5Very high157 Ų15786 Ų8696%0.96344%0.442SS*.THydrogen-bonded Turntrans-61.3-26.8179.947.60000113.8G340T338-G340 VanDerWaalsContact C-N 3.27Å
339D91.2Very high92.8Very high85 Ų8581.5 Ų81.546%0.45542%0.42SS..THydrogen-bonded Turntrans-83.92.7172.465.8-21.8000113.4S337 R341S337-D339 VanDerWaalsContact CB-OD1 3.24Å; S337-D339 WeakPolarHBondContact CB-OD1 3.48Å; S337-D339 PolarHBondContact O-N 2.94Å; S337-D339 PolarHBondContact OG-OD1 3.01Å; D339-R341 VanDerWaalsContact OD2-CD 3.23Å; D339-R341 WeakPolarHBondContact OD2-CD 3.46Å; D339-R341 IonicContact OD2-CZ 2.78Å; D339-R341 VanDerWaalsContact OD2-CZ 3.26Å; D339-R341 IonicContact OD2-NE 3.83Å; D339-R341 PolarHBondContact OD2-NE 3.43Å; D339-R341 IonicContact OD2-NH1 3.76Å; D339-R341 PolarHBondContact OD2-NH1 2.91Å
340G90.5Very high93.1Very high22 Ų2280.4 Ų80.423%0.22741%0.411CS..SBendtrans80.427.417500000114.5L336 S337 T338L336-G340 WeakPolarHBondContact CD1-O 3.45Å; S337-G340 WeakPolarHBondContact O-CA 3.14Å; S337-G340 PolarHBondContact O-N 3.27Å; T338-G340 VanDerWaalsContact C-N 3.27Å
341R93.9Very high93.2Very high170 Ų17073.2 Ų73.264%0.64239%0.385SS*.  trans-103.8144.3176-61.2179.7176.8147.7-11.7110.7L336 S337 D339 V343L336-R341 WeakPolarHBondContact CA-O 3.29Å; S337-R341 PolarHBondContact N-O 3.45Å; S337-R341 WeakPolarHBondContact OG-CB 3.31Å; S337-R341 PolarHBondContact OG-N 2.7Å; S337-R341 VanDerWaalsContact OG-N 3.16Å; S337-R341 PolarHBondContact OG-O 2.81Å; D339-R341 VanDerWaalsContact OD2-CD 3.23Å; D339-R341 WeakPolarHBondContact OD2-CD 3.46Å; D339-R341 IonicContact OD2-CZ 2.78Å; D339-R341 VanDerWaalsContact OD2-CZ 3.26Å; D339-R341 IonicContact OD2-NE 3.83Å; D339-R341 PolarHBondContact OD2-NE 3.43Å; D339-R341 IonicContact OD2-NH1 3.76Å; D339-R341 PolarHBondContact OD2-NH1 2.91Å; R341-V343 PolarHBondContact O-N 2.94Å
342L94.5Very high93.2Very high110 Ų11072.4 Ų72.458%0.57638%0.382SS*.EExtended strand (participates in β ladder)trans-75.5124174.2-179.959.3000109.7D187 P334D187-L342 HydrophobicContact CB-CD1 4.16Å; D187-L342 WeakPolarHBondContact O-CD1 3.44Å; P334-L342 HydrophobicContact CB-CD1 3.77Å
343V95Very high93.1Very high52 Ų5267.7 Ų67.732%0.31536%0.362SS..EExtended strand (participates in β ladder)trans-118127.3-179.5179.90000109.6P334 F335 R341P334-V343 VanDerWaalsContact CA-O 3.31Å; P334-V343 WeakPolarHBondContact CA-O 3.1Å; F335-V343 HydrophobicContact CD1-CB 4.28Å; F335-V343 HydrophobicContact CE1-CB 3.82Å; F335-V343 HydrophobicContact CE1-CG1 3.7Å; F335-V343 HydrophobicContact CE2-CB 4.45Å; F335-V343 HydrophobicContact CZ-CB 3.92Å; F335-V343 HydrophobicContact CZ-CG1 3.86Å; F335-V343 PolarHBondContact N-O 3.17Å; F335-V343 PolarHBondContact O-N 3.03Å; R341-V343 PolarHBondContact O-N 2.94Å
344T93.8Very high93Very high106 Ų10670.1 Ų70.165%0.6537%0.374SS*.  trans-91.2117.3167.2-61.20000108.6
345P93.2Very high93Very high15 Ų1568.6 Ų68.610%0.09736%0.362CS..  trans-78.5146.4-173.129.9-34.3000112.9K332 I333 F335 K347 N349K332-P345 HydrophobicContact CB-CG 4.05Å; K332-P345 WeakPolarHBondContact CD-O 3.39Å; I333-P345 WeakPolarHBondContact O-CG 3.43Å; F335-P345 HydrophobicContact CD1-CG 4.46Å; F335-P345 HydrophobicContact CE1-CB 4.09Å; F335-P345 HydrophobicContact CE1-CG 4.49Å; P345-K347 VanDerWaalsContact C-N 3.33Å; P345-K347 WeakPolarHBondContact CB-O 3.3Å; P345-N349 HydrophobicContact CB-CB 4.32Å; P345-N349 HydrophobicContact CG-CB 4.36Å; P345-N349 WeakPolarHBondContact CG-OD1 3.29Å
346D93Very high92.9Very high144 Ų14467.3 Ų67.377%0.7736%0.356SS*.SBendtrans-74.9-22.8176.7-63.5-39.9000113.5K332K332-D346 WeakPolarHBondContact CE-O 3.28Å; K332-D346 PolarHBondContact NZ-O 3.08Å
347K93.7Very high93Very high173 Ų17365.4 Ų65.475%0.75235%0.346SS*.SBendtrans-128160.3-179.7-64-178.9-177176.40110.2P345 N349P345-K347 VanDerWaalsContact C-N 3.33Å; P345-K347 WeakPolarHBondContact CB-O 3.3Å; K347-N349 PolarHBondContact O-N 3.01Å
348A93.7Very high93.2Very high51 Ų5164.8 Ų64.842%0.42134%0.34SS..  trans-60.7124.7175.400000110.1R330 K331R330-A348 HydrophobicContact CB-CB 4.37Å; K331-A348 VanDerWaalsContact O-CA 3.29Å; K331-A348 WeakPolarHBondContact O-CA 3.27Å
349N95.1Very high93.5Very high31 Ų3158.6 Ų58.617%0.16630%0.301CS..  trans-116.8-5.6-17465.4-42.6000113.2N180 K331 I333 F335 P345 K347N180-N349 PolarHBondContact N-O 3.3Å; K331-N349 PolarHBondContact O-N 3.08Å; K331-N349 PolarHBondContact O-OD1 3.41Å; I333-N349 PolarHBondContact N-OD1 3.47Å; I333-N349 PolarHBondContact O-ND2 3.26Å; I333-N349 PolarHBondContact O-OD1 2.78Å; F335-N349 WeakPolarHBondContact CD1-ND2 3.49Å; P345-N349 HydrophobicContact CB-CB 4.32Å; P345-N349 HydrophobicContact CG-CB 4.36Å; P345-N349 WeakPolarHBondContact CG-OD1 3.29Å; K347-N349 PolarHBondContact O-N 3.01Å
350G93.9Very high93.7Very high0 Ų054.6 Ų54.60%028%0.28CS..EExtended strand (participates in β ladder)trans-166.8-168.3-178.200000113.7F178 R330 K331F178-G350 CarbonylContact O-C 3.38Å; F178-G350 WeakPolarHBondContact O-CA 3.44Å; R330-G350 WeakPolarHBondContact CA-O 3.34Å; K331-G350 PolarHBondContact N-O 2.81Å; K331-G350 PolarHBondContact O-N 3.02Å
351F93.3Very high93.9Very high29 Ų2953.6 Ų53.613%0.12727%0.269CS..EExtended strand (participates in β ladder)trans-125.5140.5-173.2-53.8-88.7000111.4F178 M328 A329 R330F178-F351 PolarHBondContact N-O 2.92Å; F178-F351 PolarHBondContact O-N 3.18Å; M328-F351 HydrophobicContact CB-CD1 4.29Å; M328-F351 HydrophobicContact CE-CD1 3.54Å; M328-F351 HydrophobicContact CE-CD2 4.47Å; M328-F351 HydrophobicContact CE-CE1 3.48Å; M328-F351 VanDerWaalsContact CE-CE1 3.48Å; M328-F351 HydrophobicContact CE-CE2 4.42Å; M328-F351 HydrophobicContact CE-CG 4.05Å; M328-F351 HydrophobicContact CE-CZ 3.96Å; A329-F351 WeakPolarHBondContact O-CA 3.43Å; R330-F351 HydrophobicContact CG-CD1 3.49Å; R330-F351 VanDerWaalsContact CG-CD1 3.49Å; R330-F351 HydrophobicContact CG-CE1 3.23Å; R330-F351 HydrophobicContact CG-CZ 4.12Å; R330-F351 VanDerWaalsContact NE-CE1 3.26Å
352K91.9Very high93.9Very high60 Ų6047.6 Ų47.626%0.26125%0.252SS..EExtended strand (participates in β ladder)trans-101.7145.9160.6-61.4-170.9174.8-166.60108.7A195 A329 K331 I333A195-K352 HydrophobicContact CB-CD 3.61Å; A195-K352 HydrophobicContact CB-CG 4.17Å; A329-K352 PolarHBondContact N-O 3Å; A329-K352 PolarHBondContact O-N 3.48Å; K331-K352 HydrophobicContact CB-CG 4.49Å; K331-K352 HydrophobicContact CG-CD 4.08Å; K331-K352 HydrophobicContact CG-CG 4.14Å; I333-K352 HydrophobicContact CD1-CG 4.22Å; I333-K352 HydrophobicContact CG1-CG 4.48Å
353L90.9Very high93.8Very high30 Ų3046.3 Ų46.316%0.15724%0.24CC..EExtended strand (participates in β ladder)trans-105.6124.3175.3-59.1-177.4000109.1M175 F178 Y326 M328M175-L353 HydrophobicContact CE-CD1 3.95Å; F178-L353 HydrophobicContact CD2-CD1 4.16Å; F178-L353 HydrophobicContact CD2-CG 4.34Å; F178-L353 HydrophobicContact CE2-CD1 3.69Å; F178-L353 HydrophobicContact CE2-CG 4.27Å; Y326-L353 HydrophobicContact CD1-CB 3.74Å; Y326-L353 HydrophobicContact CE1-CB 4.4Å; Y326-L353 HydrophobicContact CG-CB 4.29Å; M328-L353 HydrophobicContact CB-CD2 4.5Å; M328-L353 HydrophobicContact CG-CD2 3.53Å
354E91Very high93.8Very high55 Ų5544.6 Ų44.626%0.25723%0.231SC..EExtended strand (participates in β ladder)trans-128.2138.3-178.5-65.9178.7-168.100109.6H327H327-E354 WeakPolarHBondContact CB-O 3.14Å; H327-E354 PolarHBondContact CD2-O 2.64Å; H327-E354 PolarHBondContact N-O 3.18Å; H327-E354 PolarHBondContact O-N 2.97Å
355K93.3Very high93.8Very high23 Ų2347.4 Ų47.410%0.123%0.234CC..  trans-92.1146.2165.4-67.9171-178.9164.80108.6D197 G198 N199 G200 E204 L324 Y326D197-K355 PolarHBondContact O-N 3.28Å; G198-K355 CarbonylContact C-O 3.58Å; N199-K355 PolarHBondContact N-O 2.8Å; N199-K355 PolarHBondContact OD1-O 2.79Å; G200-K355 WeakPolarHBondContact CA-O 3.38Å; G200-K355 PolarHBondContact N-O 3.44Å; E204-K355 IonicContact OE2-NZ 3.21Å; E204-K355 PolarHBondContact OE2-NZ 3.02Å; L324-K355 HydrophobicContact CB-CD 4.25Å; L324-K355 HydrophobicContact CB-CG 4.29Å; Y326-K355 HydrophobicContact CD1-CG 4.06Å; Y326-K355 HydrophobicContact CE1-CD 4.35Å; Y326-K355 HydrophobicContact CE1-CG 4.02Å; Y326-K355 VanDerWaalsContact CZ-CE 3.5Å; Y326-K355 WeakPolarHBondContact OH-CE 3.19Å
356F94.7Very high93.8Very high37 Ų3751.6 Ų51.616%0.16225%0.251CS..  trans-102.7140.5173.4-63.1-41.2000112.8N199 E279 H327 F358 D359N199-F356 VanDerWaalsContact OD1-CA 3.31Å; N199-F356 WeakPolarHBondContact OD1-CA 3.35Å; E279-F356 HydrophobicContact CG-CD2 4.5Å; E279-F356 HydrophobicContact CG-CE2 4.03Å; H327-F356 HydrophobicContact CB-CD2 4.34Å; H327-F356 HydrophobicContact CB-CE2 3.71Å; H327-F356 HydrophobicContact CB-CZ 3.94Å; H327-F356 AromaticContact CD2-CD2 3.24Å; H327-F356 WeakPolarHBondContact CD2-CD2 3.39Å; H327-F356 AromaticContact CD2-CE2 3.53Å; H327-F356 AromaticContact CD2-CG 3.83Å; H327-F356 AromaticContact CE1-CD2 3.58Å; H327-F356 AromaticContact CE1-CE2 3.83Å; H327-F356 AromaticContact CG-CD2 3.54Å; H327-F356 AromaticContact CG-CE2 3.3Å; H327-F356 AromaticContact ND1-CD2 3.78Å; H327-F356 AromaticContact ND1-CE2 3.55Å; H327-F356 AromaticContact NE2-CD2 3.26Å; H327-F356 VanDerWaalsContact NE2-CD2 3.26Å; H327-F356 WeakPolarHBondContact NE2-CD2 3.44Å; H327-F356 AromaticContact NE2-CE2 3.84Å; F356-F358 HydrophobicContact CB-CD1 4.09Å; F356-F358 HydrophobicContact CB-CD2 3.97Å; F356-F358 HydrophobicContact CB-CE1 3.69Å; F356-F358 HydrophobicContact CB-CE2 3.55Å; F356-F358 HydrophobicContact CB-CG 4.24Å; F356-F358 HydrophobicContact CB-CZ 3.42Å; F356-F358 VanDerWaalsContact CB-CZ 3.42Å; F356-F358 HydrophobicContact CD2-CE1 4.21Å; F356-F358 AromaticContact CD2-CE2 3.75Å; F356-F358 HydrophobicContact CD2-CE2 3.75Å; F356-F358 AromaticContact CD2-CZ 3.34Å; F356-F358 HydrophobicContact CD2-CZ 3.34Å; F356-F358 HydrophobicContact CE2-CZ 4.23Å; F356-F358 AromaticContact CG-CE1 3.97Å; F356-F358 HydrophobicContact CG-CE1 3.97Å; F356-F358 HydrophobicContact CG-CE2 4.02Å; F356-F358 AromaticContact CG-CZ 3.52Å; F356-F358 HydrophobicContact CG-CZ 3.52Å; F356-F358 PolarHBondContact O-N 3.18Å; F356-D359 PolarHBondContact N-OD2 2.92Å; F356-D359 WeakPolarHBondContact O-CB 3.09Å; F356-D359 PolarHBondContact O-N 2.8Å; F356-D359 VanDerWaalsContact O-N 3.1Å
357I95.8Very high93.9Very high0 Ų045.9 Ų45.90%022%0.219CC..G310 helixtrans-58.9-32.2-178.1-173.6169.6000112.3L83 N199 L202 Y203 V225 H307 F309 D359 V360L83-I357 HydrophobicContact CD1-CD1 3.58Å; L83-I357 HydrophobicContact CD2-CD1 4.37Å; N199-I357 PolarHBondContact OD1-N 3.37Å; L202-I357 HydrophobicContact CD2-CD1 3.78Å; L202-I357 HydrophobicContact CD2-CG1 4.26Å; Y203-I357 HydrophobicContact CE2-CG1 4.46Å; Y203-I357 WeakPolarHBondContact OH-CG1 3.41Å; Y203-I357 PolarHBondContact OH-O 2.77Å; V225-I357 HydrophobicContact CB-CD1 4.22Å; V225-I357 HydrophobicContact CG1-CD1 3.48Å; V225-I357 VanDerWaalsContact CG1-CD1 3.48Å; H307-I357 VanDerWaalsContact CE1-CG2 3.47Å; H307-I357 WeakPolarHBondContact CE1-CG2 3.4Å; F309-I357 HydrophobicContact CE2-CD1 4.41Å; F309-I357 HydrophobicContact CZ-CG1 4.48Å; I357-D359 VanDerWaalsContact C-N 3.32Å; I357-D359 PolarHBondContact O-N 3.43Å; I357-V360 WeakPolarHBondContact O-CG2 3.19Å
358F95.7Very high94Very high11 Ų1137.7 Ų37.75%0.04818%0.183CC..G310 helixtrans-80.4-9.5-178.452.1-110.7000113.8V277 E279 N303 F356 V360 F361V277-F358 HydrophobicContact CB-CB 4.22Å; V277-F358 HydrophobicContact CB-CD1 4.16Å; V277-F358 HydrophobicContact CB-CD2 3.55Å; V277-F358 HydrophobicContact CB-CE1 4.37Å; V277-F358 HydrophobicContact CB-CE2 3.81Å; V277-F358 HydrophobicContact CB-CG 3.72Å; V277-F358 HydrophobicContact CB-CZ 4.2Å; V277-F358 HydrophobicContact CG1-CD1 4.24Å; V277-F358 HydrophobicContact CG1-CD2 4.3Å; V277-F358 HydrophobicContact CG1-CE1 4.11Å; V277-F358 HydrophobicContact CG1-CE2 4.19Å; V277-F358 HydrophobicContact CG1-CG 4.3Å; V277-F358 HydrophobicContact CG1-CZ 4.07Å; V277-F358 HydrophobicContact CG2-CB 3.7Å; V277-F358 HydrophobicContact CG2-CD1 4.25Å; V277-F358 HydrophobicContact CG2-CD2 4.03Å; V277-F358 HydrophobicContact CG2-CG 3.74Å; E279-F358 HydrophobicContact CG-CZ 4.05Å; E279-F358 VanDerWaalsContact OE1-CE1 3.31Å; E279-F358 WeakPolarHBondContact OE1-CE1 3.23Å; E279-F358 WeakPolarHBondContact OE1-CZ 3.34Å; N303-F358 VanDerWaalsContact ND2-CD1 3.32Å; N303-F358 WeakPolarHBondContact ND2-CD1 3.5Å; F356-F358 HydrophobicContact CB-CD1 4.09Å; F356-F358 HydrophobicContact CB-CD2 3.97Å; F356-F358 HydrophobicContact CB-CE1 3.69Å; F356-F358 HydrophobicContact CB-CE2 3.55Å; F356-F358 HydrophobicContact CB-CG 4.24Å; F356-F358 HydrophobicContact CB-CZ 3.42Å; F356-F358 VanDerWaalsContact CB-CZ 3.42Å; F356-F358 HydrophobicContact CD2-CE1 4.21Å; F356-F358 AromaticContact CD2-CE2 3.75Å; F356-F358 HydrophobicContact CD2-CE2 3.75Å; F356-F358 AromaticContact CD2-CZ 3.34Å; F356-F358 HydrophobicContact CD2-CZ 3.34Å; F356-F358 HydrophobicContact CE2-CZ 4.23Å; F356-F358 AromaticContact CG-CE1 3.97Å; F356-F358 HydrophobicContact CG-CE1 3.97Å; F356-F358 HydrophobicContact CG-CE2 4.02Å; F356-F358 AromaticContact CG-CZ 3.52Å; F356-F358 HydrophobicContact CG-CZ 3.52Å; F356-F358 PolarHBondContact O-N 3.18Å; F358-V360 PolarHBondContact O-N 2.81Å; F358-F361 HydrophobicContact CB-CD1 4.35Å; F358-F361 HydrophobicContact CB-CD2 4.05Å; F358-F361 HydrophobicContact CB-CE1 3.91Å; F358-F361 HydrophobicContact CB-CE2 3.6Å; F358-F361 HydrophobicContact CB-CG 4.41Å; F358-F361 HydrophobicContact CB-CZ 3.5Å; F358-F361 WeakPolarHBondContact O-CB 3.16Å; F358-F361 WeakPolarHBondContact O-CD1 3.37Å; F358-F361 WeakPolarHBondContact O-CG 3.15Å; F358-F361 PolarHBondContact O-N 3.06Å
359D94.9Very high94Very high27 Ų2735.5 Ų35.514%0.14417%0.165CC..G310 helixtrans-66.3-9.5179.2-69.9-34.2000112.8L324 P325 H327 F356 I357 P362L324-D359 HydrophobicContact CB-CB 4.33Å; L324-D359 HydrophobicContact CD1-CB 4.43Å; L324-D359 HydrophobicContact CD2-CB 3.95Å; L324-D359 HydrophobicContact CG-CB 4.46Å; P325-D359 HydrophobicContact CG-CB 4.33Å; H327-D359 IonicContact CD2-OD2 3.9Å; H327-D359 PolarHBondContact CD2-OD2 2.85Å; H327-D359 IonicContact CE1-OD2 3.42Å; H327-D359 IonicContact NE2-OD1 3.35Å; H327-D359 IonicContact NE2-OD2 2.65Å; H327-D359 PolarHBondContact NE2-OD2 3.49Å; F356-D359 PolarHBondContact N-OD2 2.92Å; F356-D359 WeakPolarHBondContact O-CB 3.09Å; F356-D359 PolarHBondContact O-N 2.8Å; F356-D359 VanDerWaalsContact O-N 3.1Å; I357-D359 VanDerWaalsContact C-N 3.32Å; I357-D359 PolarHBondContact O-N 3.43Å; D359-P362 WeakPolarHBondContact O-CD 3.24Å
360V95.9Very high94Very high1 Ų134 Ų341%0.00616%0.157CC..G310 helixtrans-79.1-14.9171-62.80000114Y203 F309 F313 V317 L324 I357 F358 P362 Y363Y203-V360 HydrophobicContact CD1-CG1 4.21Å; Y203-V360 HydrophobicContact CD2-CG1 3.69Å; Y203-V360 HydrophobicContact CE1-CG1 3.81Å; Y203-V360 HydrophobicContact CE1-CG2 4.23Å; Y203-V360 HydrophobicContact CE2-CB 4.33Å; Y203-V360 HydrophobicContact CE2-CG1 3.22Å; Y203-V360 HydrophobicContact CE2-CG2 4.28Å; Y203-V360 HydrophobicContact CG-CG1 4.16Å; Y203-V360 WeakPolarHBondContact OH-CG2 3.35Å; F309-V360 HydrophobicContact CE1-CG2 3.87Å; F309-V360 HydrophobicContact CZ-CG2 4.16Å; F313-V360 HydrophobicContact CE1-CB 4.3Å; F313-V360 HydrophobicContact CE1-CG2 3.92Å; F313-V360 HydrophobicContact CZ-CB 4.14Å; F313-V360 HydrophobicContact CZ-CG2 4.09Å; V317-V360 HydrophobicContact CB-CG1 4.32Å; V317-V360 HydrophobicContact CG1-CB 4.42Å; V317-V360 HydrophobicContact CG1-CG1 4.46Å; V317-V360 HydrophobicContact CG2-CG1 4.27Å; L324-V360 HydrophobicContact CD1-CG1 3.92Å; L324-V360 HydrophobicContact CD2-CG1 3.81Å; L324-V360 HydrophobicContact CG-CG1 4.44Å; I357-V360 WeakPolarHBondContact O-CG2 3.19Å; F358-V360 PolarHBondContact O-N 2.81Å; V360-P362 VanDerWaalsContact C-N 3.28Å; V360-Y363 WeakPolarHBondContact O-CB 3.26Å; V360-Y363 WeakPolarHBondContact O-CD2 3.36Å; V360-Y363 PolarHBondContact O-N 2.86Å
361F95.4Very high93.9Very high0 Ų034.9 Ų34.90%016%0.161CC..G310 helixtrans-52.8-41-174.9-65.3-4.4000112.9V253 P275 V277 H307 F358 Y363 S364 F367V253-F361 HydrophobicContact CB-CE2 4.36Å; V253-F361 HydrophobicContact CB-CZ 3.94Å; V253-F361 HydrophobicContact CG1-CE2 4.31Å; V253-F361 HydrophobicContact CG1-CZ 4.37Å; V253-F361 HydrophobicContact CG2-CE2 4.47Å; V253-F361 HydrophobicContact CG2-CZ 4.04Å; P275-F361 HydrophobicContact CB-CB 4.19Å; P275-F361 HydrophobicContact CG-CB 4.15Å; P275-F361 WeakPolarHBondContact CG-O 3.09Å; P275-F361 WeakPolarHBondContact O-CB 3.48Å; V277-F361 HydrophobicContact CG2-CD2 3.99Å; V277-F361 HydrophobicContact CG2-CE2 3.53Å; H307-F361 AromaticContact CD2-CE1 3.65Å; H307-F361 AromaticContact CD2-CZ 3.47Å; H307-F361 VanDerWaalsContact CD2-CZ 3.47Å; H307-F361 WeakPolarHBondContact CD2-CZ 3.4Å; H307-F361 AromaticContact NE2-CZ 3.57Å; F358-F361 HydrophobicContact CB-CD1 4.35Å; F358-F361 HydrophobicContact CB-CD2 4.05Å; F358-F361 HydrophobicContact CB-CE1 3.91Å; F358-F361 HydrophobicContact CB-CE2 3.6Å; F358-F361 HydrophobicContact CB-CG 4.41Å; F358-F361 HydrophobicContact CB-CZ 3.5Å; F358-F361 WeakPolarHBondContact O-CB 3.16Å; F358-F361 WeakPolarHBondContact O-CD1 3.37Å; F358-F361 WeakPolarHBondContact O-CG 3.15Å; F358-F361 PolarHBondContact O-N 3.06Å; F361-Y363 PolarHBondContact O-N 3.3Å; F361-S364 VanDerWaalsContact O-CB 3.26Å; F361-S364 WeakPolarHBondContact O-CB 3.42Å; F361-S364 PolarHBondContact O-N 3.48Å; F361-F367 HydrophobicContact CB-CD2 4.37Å; F361-F367 HydrophobicContact CB-CE2 3.95Å; F361-F367 HydrophobicContact CB-CZ 4.41Å; F361-F367 HydrophobicContact CD1-CD2 4.5Å; F361-F367 AromaticContact CD1-CE2 3.63Å; F361-F367 HydrophobicContact CD1-CE2 3.63Å; F361-F367 HydrophobicContact CD1-CZ 4.32Å; F361-F367 HydrophobicContact CD2-CE1 4.49Å; F361-F367 AromaticContact CD2-CE2 3.62Å; F361-F367 HydrophobicContact CD2-CE2 3.62Å; F361-F367 AromaticContact CD2-CZ 3.46Å; F361-F367 HydrophobicContact CD2-CZ 3.46Å; F361-F367 VanDerWaalsContact CD2-CZ 3.46Å; F361-F367 AromaticContact CE1-CE2 3.98Å; F361-F367 HydrophobicContact CE1-CE2 3.98Å; F361-F367 HydrophobicContact CE1-CZ 4.48Å; F361-F367 AromaticContact CE2-CE2 3.94Å; F361-F367 HydrophobicContact CE2-CE2 3.94Å; F361-F367 AromaticContact CE2-CZ 3.65Å; F361-F367 HydrophobicContact CE2-CZ 3.65Å; F361-F367 HydrophobicContact CG-CD2 4.31Å; F361-F367 AromaticContact CG-CE2 3.45Å; F361-F367 HydrophobicContact CG-CE2 3.45Å; F361-F367 VanDerWaalsContact CG-CE2 3.45Å; F361-F367 AromaticContact CG-CZ 3.83Å; F361-F367 HydrophobicContact CG-CZ 3.83Å; F361-F367 HydrophobicContact CZ-CE2 4.13Å; F361-F367 HydrophobicContact CZ-CZ 4.18Å
362P92.6Very high94Very high44 Ų4433.8 Ų33.829%0.28616%0.157SC..G310 helixtrans-59.9-13.4176.7-26.236.7000116K274 P275 D359 V360K274-P362 HydrophobicContact CB-CB 4.1Å; K274-P362 HydrophobicContact CD-CB 3.77Å; P275-P362 WeakPolarHBondContact O-CD 3.47Å; P275-P362 WeakPolarHBondContact O-CG 3.24Å; D359-P362 WeakPolarHBondContact O-CD 3.24Å; V360-P362 VanDerWaalsContact C-N 3.28Å
363Y93.9Very high94.1Very high83 Ų8332.5 Ų32.533%0.32515%0.153SC..G310 helixtrans-92.1-10.7176.6-60.1-87.1000113.3V317 C322 Q323 L324 V360 F361V317-Y363 HydrophobicContact CG1-CG 4.5Å; C322-Y363 HydrophobicContact CB-CD1 4.36Å; C322-Y363 HydrophobicContact CB-CE1 3.89Å; C322-Y363 HydrophobicContact CB-CE2 4.13Å; C322-Y363 VanDerWaalsContact SG-CE1 3.55Å; Q323-Y363 PolarHBondContact O-OH 2.66Å; L324-Y363 HydrophobicContact CD2-CE2 4.04Å; V360-Y363 WeakPolarHBondContact O-CB 3.26Å; V360-Y363 WeakPolarHBondContact O-CD2 3.36Å; V360-Y363 PolarHBondContact O-N 2.86Å; F361-Y363 PolarHBondContact O-N 3.3Å
364S94.6Very high94.3Very high17 Ų1733.1 Ų33.112%0.11915%0.153CC..  trans-68.3136.9176.1170.70000110.5D250 F361 K366 F367D250-S364 WeakPolarHBondContact OD1-CB 3.41Å; D250-S364 PolarHBondContact OD1-OG 3Å; F361-S364 VanDerWaalsContact O-CB 3.26Å; F361-S364 WeakPolarHBondContact O-CB 3.42Å; F361-S364 PolarHBondContact O-N 3.48Å; S364-K366 VanDerWaalsContact OG-C 3.3Å; S364-K366 PolarHBondContact OG-N 3.02Å; S364-F367 VanDerWaalsContact OG-CA 3.31Å; S364-F367 WeakPolarHBondContact OG-CA 3.35Å; S364-F367 WeakPolarHBondContact OG-CB 3.38Å; S364-F367 PolarHBondContact OG-N 3.34Å
365K92.6Very high94.6Very high164 Ų16436.5 Ų36.571%0.71317%0.169SC*.SBendtrans-91.9-25.2172.3-63.8176.3-177.7170.40111.2D250D250-K365 WeakPolarHBondContact OD2-CB 3.45Å; D250-K365 PolarHBondContact OD2-N 3.42Å
366K94.3Very high94.7Very high104 Ų10437.6 Ų37.645%0.45217%0.174SC..SBendtrans-137.270.6-176.2-65.4179.3-177.1169.50109.7D248 A249 D250 S364D248-K366 HydrophobicContact CB-CD 4.39Å; D248-K366 VanDerWaalsContact O-CB 3.3Å; D248-K366 WeakPolarHBondContact O-CB 3.4Å; D248-K366 WeakPolarHBondContact O-CD 3.5Å; D248-K366 IonicContact OD2-NZ 3.19Å; D248-K366 PolarHBondContact OD2-NZ 3.46Å; A249-K366 WeakPolarHBondContact CA-O 3.3Å; A249-K366 WeakPolarHBondContact CB-O 3.45Å; D250-K366 PolarHBondContact N-O 3.34Å; D250-K366 PolarHBondContact OD1-N 2.92Å; D250-K366 VanDerWaalsContact OD1-N 3.12Å; D250-K366 PolarHBondContact OD2-N 3.27Å; S364-K366 VanDerWaalsContact OG-C 3.3Å; S364-K366 PolarHBondContact OG-N 3.02Å
367F95.6Very high94.8Very high24 Ų2436 Ų3611%0.10517%0.167CC..EExtended strand (participates in β ladder)trans-78135.4-179.6-169.9-105.7000111.7C49 C251 V253 I268 P275 F361 S364 V369C49-F367 PolarHBondContact SG-O 3.49Å; C251-F367 HydrophobicContact CB-CD2 4.12Å; C251-F367 VanDerWaalsContact O-CA 3.32Å; C251-F367 WeakPolarHBondContact O-CA 3.29Å; V253-F367 HydrophobicContact CB-CZ 4.29Å; V253-F367 HydrophobicContact CG1-CE1 4.13Å; V253-F367 HydrophobicContact CG1-CE2 4.28Å; V253-F367 HydrophobicContact CG1-CZ 3.48Å; V253-F367 VanDerWaalsContact CG1-CZ 3.48Å; I268-F367 HydrophobicContact CG2-CE1 4.25Å; P275-F367 HydrophobicContact CB-CB 4.21Å; P275-F367 HydrophobicContact CB-CD1 3.37Å; P275-F367 HydrophobicContact CB-CD2 4.22Å; P275-F367 HydrophobicContact CB-CE1 3.64Å; P275-F367 HydrophobicContact CB-CE2 4.45Å; P275-F367 HydrophobicContact CB-CG 3.67Å; P275-F367 HydrophobicContact CB-CZ 4.18Å; P275-F367 HydrophobicContact CG-CB 3.83Å; P275-F367 HydrophobicContact CG-CD1 3.97Å; P275-F367 HydrophobicContact CG-CD2 4.19Å; P275-F367 HydrophobicContact CG-CG 3.74Å; F361-F367 HydrophobicContact CB-CD2 4.37Å; F361-F367 HydrophobicContact CB-CE2 3.95Å; F361-F367 HydrophobicContact CB-CZ 4.41Å; F361-F367 HydrophobicContact CD1-CD2 4.5Å; F361-F367 AromaticContact CD1-CE2 3.63Å; F361-F367 HydrophobicContact CD1-CE2 3.63Å; F361-F367 HydrophobicContact CD1-CZ 4.32Å; F361-F367 HydrophobicContact CD2-CE1 4.49Å; F361-F367 AromaticContact CD2-CE2 3.62Å; F361-F367 HydrophobicContact CD2-CE2 3.62Å; F361-F367 AromaticContact CD2-CZ 3.46Å; F361-F367 HydrophobicContact CD2-CZ 3.46Å; F361-F367 VanDerWaalsContact CD2-CZ 3.46Å; F361-F367 AromaticContact CE1-CE2 3.98Å; F361-F367 HydrophobicContact CE1-CE2 3.98Å; F361-F367 HydrophobicContact CE1-CZ 4.48Å; F361-F367 AromaticContact CE2-CE2 3.94Å; F361-F367 HydrophobicContact CE2-CE2 3.94Å; F361-F367 AromaticContact CE2-CZ 3.65Å; F361-F367 HydrophobicContact CE2-CZ 3.65Å; F361-F367 HydrophobicContact CG-CD2 4.31Å; F361-F367 AromaticContact CG-CE2 3.45Å; F361-F367 HydrophobicContact CG-CE2 3.45Å; F361-F367 VanDerWaalsContact CG-CE2 3.45Å; F361-F367 AromaticContact CG-CZ 3.83Å; F361-F367 HydrophobicContact CG-CZ 3.83Å; F361-F367 HydrophobicContact CZ-CE2 4.13Å; F361-F367 HydrophobicContact CZ-CZ 4.18Å; S364-F367 VanDerWaalsContact OG-CA 3.31Å; S364-F367 WeakPolarHBondContact OG-CA 3.35Å; S364-F367 WeakPolarHBondContact OG-CB 3.38Å; S364-F367 PolarHBondContact OG-N 3.34Å; F367-V369 HydrophobicContact CD1-CG2 4.17Å; F367-V369 HydrophobicContact CE1-CG2 3.5Å; F367-V369 HydrophobicContact CZ-CG2 4.27Å
368A94.9Very high94.9Very high0 Ų037 Ų370%017%0.172CC..EExtended strand (participates in β ladder)trans-129.5148.5176.500000112.1K50 F243 A249 C251 A252 V253K50-A368 HydrophobicContact CB-CB 4.26Å; F243-A368 HydrophobicContact CE1-CB 3.75Å; F243-A368 HydrophobicContact CZ-CB 3.93Å; A249-A368 HydrophobicContact CB-CB 3.79Å; C251-A368 PolarHBondContact O-N 2.83Å; C251-A368 VanDerWaalsContact O-N 3.11Å; A252-A368 WeakPolarHBondContact CA-O 3.05Å; A252-A368 HydrophobicContact CB-CB 4.08Å; V253-A368 PolarHBondContact N-O 3.14Å
369V94Very high95Very high5 Ų536.6 Ų36.63%0.0317%0.17CC..EExtended strand (participates in β ladder)trans-122.8128.3176.4178.90000108.5K50 C51 C52 V253 S255 I268 F367K50-V369 PolarHBondContact O-N 3.25Å; C51-V369 VanDerWaalsContact CA-O 3.31Å; C51-V369 WeakPolarHBondContact CA-O 3.44Å; C52-V369 PolarHBondContact N-O 3.47Å; V253-V369 HydrophobicContact CG1-CB 4.47Å; V253-V369 HydrophobicContact CG1-CG1 4.43Å; V253-V369 HydrophobicContact CG1-CG2 3.89Å; V253-V369 WeakPolarHBondContact O-CA 3.47Å; S255-V369 WeakPolarHBondContact OG-CG1 3.32Å; I268-V369 HydrophobicContact CD1-CG1 4.27Å; I268-V369 HydrophobicContact CG2-CG2 3.87Å; F367-V369 HydrophobicContact CD1-CG2 4.17Å; F367-V369 HydrophobicContact CE1-CG2 3.5Å; F367-V369 HydrophobicContact CZ-CG2 4.27Å
370L93.9Very high95.1Very high0 Ų035.6 Ų35.60%017%0.165CC..EExtended strand (participates in β ladder)trans-111.8106.8174.2176.757.1000109.9C52 R54 W239 F240 F243 V253 K254 S255 V372C52-L370 HydrophobicContact CB-CD1 4.18Å; R54-L370 HydrophobicContact CB-CD1 4.22Å; W239-L370 HydrophobicContact CE3-CD1 4.29Å; W239-L370 HydrophobicContact CE3-CD2 3.66Å; W239-L370 HydrophobicContact CH2-CD1 3.84Å; W239-L370 HydrophobicContact CZ3-CD1 3.33Å; W239-L370 HydrophobicContact CZ3-CD2 3.52Å; W239-L370 HydrophobicContact CZ3-CG 4.06Å; F240-L370 HydrophobicContact CB-CD2 4.23Å; F240-L370 HydrophobicContact CD2-CB 4.26Å; F240-L370 HydrophobicContact CD2-CD2 3.61Å; F240-L370 HydrophobicContact CE2-CB 4.21Å; F240-L370 HydrophobicContact CE2-CD2 4.37Å; F240-L370 HydrophobicContact CG-CD2 4.25Å; F243-L370 HydrophobicContact CD1-CB 4.16Å; F243-L370 HydrophobicContact CD1-CD2 4.41Å; F243-L370 HydrophobicContact CE1-CB 3.96Å; V253-L370 PolarHBondContact O-N 3.3Å; K254-L370 CarbonylContact C-O 3.51Å; K254-L370 VanDerWaalsContact CA-O 3.23Å; K254-L370 WeakPolarHBondContact CA-O 3.41Å; S255-L370 PolarHBondContact N-O 3.44Å; L370-V372 HydrophobicContact CD2-CG1 4.03Å; L370-V372 HydrophobicContact CG-CG1 3.81Å; L370-V372 PolarHBondContact O-N 2.93Å
371E93.4Very high95Very high18 Ų1835.5 Ų35.58%0.08417%0.165CC..EExtended strand (participates in β ladder)trans-74.7119.6170.1-172.8179.8103.200109.1C52 N53 R54 S255 Q301C52-E371 PolarHBondContact O-N 3.35Å; N53-E371 HydrophobicContact CB-CB 4.3Å; N53-E371 PolarHBondContact ND2-OE1 2.84Å; R54-E371 PolarHBondContact N-O 3.45Å; S255-E371 WeakPolarHBondContact O-CA 3.35Å; S255-E371 VanDerWaalsContact OG-CA 3.3Å; S255-E371 WeakPolarHBondContact OG-CA 3.25Å; Q301-E371 PolarHBondContact NE2-OE2 3.06Å; Q301-E371 PolarHBondContact OE1-OE2 3.41Å
372V94.6Very high94.9Very high7 Ų738.9 Ų38.94%0.04218%0.179CC..  trans-112.3158.9179.4-60.60000111.2K254 S255 V256 I304 L370 R374 E377K254-V372 HydrophobicContact CB-CG1 4.44Å; K254-V372 HydrophobicContact CB-CG2 4.37Å; K254-V372 HydrophobicContact CD-CG1 3.97Å; K254-V372 HydrophobicContact CD-CG2 4.47Å; K254-V372 HydrophobicContact CG-CG1 4.23Å; S255-V372 WeakPolarHBondContact O-CG2 3.45Å; S255-V372 PolarHBondContact O-N 2.8Å; V256-V372 HydrophobicContact CG1-CG2 4Å; I304-V372 HydrophobicContact CD1-CG2 4.23Å; L370-V372 HydrophobicContact CD2-CG1 4.03Å; L370-V372 HydrophobicContact CG-CG1 3.81Å; L370-V372 PolarHBondContact O-N 2.93Å; V372-R374 PolarHBondContact O-N 3.45Å; V372-E377 HydrophobicContact CB-CB 4.31Å; V372-E377 HydrophobicContact CB-CG 4.24Å; V372-E377 WeakPolarHBondContact CG1-OE1 3.36Å; V372-E377 HydrophobicContact CG2-CB 3.76Å; V372-E377 HydrophobicContact CG2-CG 4.24Å
373N94Very high94.9Very high33 Ų3339 Ų3918%0.17618%0.177CC..  trans-68.4123.4173.1-177-41000109.8E55 E375 E376 E377E55-N373 HydrophobicContact CG-CB 4.43Å; E55-N373 WeakPolarHBondContact OE1-CB 3.22Å; E55-N373 PolarHBondContact OE1-ND2 2.89Å; N373-E375 PolarHBondContact O-N 3.44Å; N373-E375 WeakPolarHBondContact OD1-CA 3.3Å; N373-E375 VanDerWaalsContact OD1-CB 3.3Å; N373-E375 WeakPolarHBondContact OD1-CB 3.46Å; N373-E375 PolarHBondContact OD1-N 3.24Å; N373-E376 HydrophobicContact CB-CB 4.24Å; N373-E376 HydrophobicContact CB-CG 4.16Å; N373-E376 PolarHBondContact O-N 3.43Å; N373-E376 PolarHBondContact OD1-N 2.82Å; N373-E377 PolarHBondContact O-N 3.2Å; N373-E377 VanDerWaalsContact O-N 3.11Å
374R95.5Very high94.8Very high42 Ų4236.5 Ų36.516%0.15817%0.174CC..Hα-helixtrans-56.4-47.3177.7175.6-178.8-68.1-97.96.1112.5V256 E257 H259 E263 V372 E376 E377 F378V256-R374 HydrophobicContact CB-CB 4.29Å; V256-R374 HydrophobicContact CG1-CB 4.2Å; E257-R374 PolarHBondContact O-NE 3.06Å; E257-R374 PolarHBondContact O-NH2 3.42Å; H259-R374 PolarHBondContact CD2-NE 3.04Å; H259-R374 PolarHBondContact NE2-NE 2.87Å; E263-R374 VanDerWaalsContact CD-NH2 3.32Å; E263-R374 IonicContact OE1-CZ 2.71Å; E263-R374 VanDerWaalsContact OE1-CZ 3.24Å; E263-R374 IonicContact OE1-NH1 2.63Å; E263-R374 PolarHBondContact OE1-NH1 2.9Å; E263-R374 IonicContact OE1-NH2 2.68Å; E263-R374 PolarHBondContact OE1-NH2 3.07Å; E263-R374 IonicContact OE2-CZ 2.69Å; E263-R374 IonicContact OE2-NH2 3.38Å; E263-R374 PolarHBondContact OE2-NH2 3.13Å; V372-R374 PolarHBondContact O-N 3.45Å; R374-E376 PolarHBondContact O-N 2.93Å; R374-E376 VanDerWaalsContact O-N 3.14Å; R374-E377 PolarHBondContact O-N 3.22Å; R374-F378 HydrophobicContact CG-CB 4.37Å; R374-F378 HydrophobicContact CG-CD1 4.39Å; R374-F378 CarbonylContact O-C 3.5Å; R374-F378 WeakPolarHBondContact O-CA 3.33Å; R374-F378 PolarHBondContact O-N 2.65Å; R374-F378 VanDerWaalsContact O-O 3.11Å
375E96.2Very high94.7Very high126 Ų12639 Ų3959%0.58919%0.186SC*.Hα-helixtrans-65.9-14.3-177.6-54.7-179.2174.600112.9N373 R405N373-E375 PolarHBondContact O-N 3.44Å; N373-E375 WeakPolarHBondContact OD1-CA 3.3Å; N373-E375 VanDerWaalsContact OD1-CB 3.3Å; N373-E375 WeakPolarHBondContact OD1-CB 3.46Å; N373-E375 PolarHBondContact OD1-N 3.24Å; E375-R405 PolarHBondContact O-NH2 3.03Å
376E96.6Very high94.7Very high47 Ų4736.5 Ų36.522%0.2219%0.189CC..Hα-helixtrans-103-24177.1-65.6-163.7177.600114.4R234 N373 R374 L402 R405R234-E376 IonicContact CZ-OE2 4Å; R234-E376 IonicContact NH2-OE2 3.53Å; R234-E376 PolarHBondContact NH2-OE2 3.38Å; N373-E376 HydrophobicContact CB-CB 4.24Å; N373-E376 HydrophobicContact CB-CG 4.16Å; N373-E376 PolarHBondContact O-N 3.43Å; N373-E376 PolarHBondContact OD1-N 2.82Å; R374-E376 PolarHBondContact O-N 2.93Å; R374-E376 VanDerWaalsContact O-N 3.14Å; E376-L402 HydrophobicContact CB-CD1 4.37Å; E376-L402 HydrophobicContact CG-CD1 4.07Å; E376-R405 IonicContact OE1-NH1 2.97Å; E376-R405 PolarHBondContact OE1-NH1 3.32Å
377E97.4Very high94.5Very high2 Ų233.8 Ų33.81%0.00919%0.187CC..Hα-helixtrans-136.8-6.1-165.2-62.7-151-138.700114.6R54 N230 R234 K254 V372 N373 R374R54-E377 IonicContact CZ-OE1 3.09Å; R54-E377 IonicContact NH1-OE1 2.56Å; R54-E377 PolarHBondContact NH1-OE1 3.05Å; N230-E377 PolarHBondContact ND2-O 3.14Å; R234-E377 HydrophobicContact CG-CG 4.31Å; K254-E377 IonicContact NZ-OE1 3.69Å; K254-E377 IonicContact NZ-OE2 3.04Å; K254-E377 PolarHBondContact NZ-OE2 3.01Å; V372-E377 HydrophobicContact CB-CB 4.31Å; V372-E377 HydrophobicContact CB-CG 4.24Å; V372-E377 WeakPolarHBondContact CG1-OE1 3.36Å; V372-E377 HydrophobicContact CG2-CB 3.76Å; V372-E377 HydrophobicContact CG2-CG 4.24Å; N373-E377 PolarHBondContact O-N 3.2Å; N373-E377 VanDerWaalsContact O-N 3.11Å; R374-E377 PolarHBondContact O-N 3.22Å
378F97.7Very high94.2Very high23 Ų2340.8 Ų40.810%0.10122%0.217CC..  trans-143.9105.5-177.3-171.7-121.6000114.1V256 I265 I304 R374 P380V256-F378 HydrophobicContact CG1-CB 3.86Å; V256-F378 HydrophobicContact CG1-CD1 4.43Å; V256-F378 HydrophobicContact CG1-CG 4.37Å; V256-F378 HydrophobicContact CG2-CD1 3.93Å; V256-F378 HydrophobicContact CG2-CE1 4.35Å; I265-F378 HydrophobicContact CD1-CE1 4.02Å; I265-F378 HydrophobicContact CD1-CZ 4.11Å; I304-F378 HydrophobicContact CB-CD2 3.62Å; I304-F378 HydrophobicContact CB-CE2 3.73Å; I304-F378 HydrophobicContact CB-CG 4.16Å; I304-F378 HydrophobicContact CB-CZ 4.34Å; I304-F378 HydrophobicContact CD1-CB 4.36Å; I304-F378 HydrophobicContact CD1-CD2 4.4Å; I304-F378 HydrophobicContact CG2-CB 4.2Å; I304-F378 HydrophobicContact CG2-CD1 3.74Å; I304-F378 HydrophobicContact CG2-CD2 3.48Å; I304-F378 VanDerWaalsContact CG2-CD2 3.48Å; I304-F378 HydrophobicContact CG2-CE1 3.87Å; I304-F378 HydrophobicContact CG2-CE2 3.63Å; I304-F378 HydrophobicContact CG2-CG 3.54Å; I304-F378 HydrophobicContact CG2-CZ 3.82Å; R374-F378 HydrophobicContact CG-CB 4.37Å; R374-F378 HydrophobicContact CG-CD1 4.39Å; R374-F378 CarbonylContact O-C 3.5Å; R374-F378 WeakPolarHBondContact O-CA 3.33Å; R374-F378 PolarHBondContact O-N 2.65Å; R374-F378 VanDerWaalsContact O-O 3.11Å; F378-P380 HydrophobicContact CE1-CG 4.02Å; F378-P380 HydrophobicContact CE2-CB 3.91Å; F378-P380 HydrophobicContact CE2-CG 3.94Å; F378-P380 HydrophobicContact CZ-CB 4Å; F378-P380 HydrophobicContact CZ-CG 3.57Å
379S97.3Very high94Very high1 Ų144.9 Ų44.91%0.00724%0.242CC..  trans-14197.2163.9-176.70000108.9N230 I231 C395 D398N230-S379 PolarHBondContact OD1-N 2.66Å; N230-S379 PolarHBondContact OD1-O 3.49Å; I231-S379 PolarHBondContact N-O 3.01Å; I231-S379 VanDerWaalsContact N-O 3.15Å; S379-C395 WeakPolarHBondContact OG-CA 3.28Å; S379-D398 WeakPolarHBondContact CB-OD2 3.3Å; S379-D398 PolarHBondContact OG-OD2 2.86Å
380P96Very high94Very high6 Ų646.4 Ų46.44%0.03925%0.25CC..BIsolated β-bridgetrans-82.2143.4-172.633.5-35.7000112.5D229 F378 K382 D390 C395D229-P380 CarbonylContact O-C 3.54Å; D229-P380 VanDerWaalsContact O-CA 3.29Å; D229-P380 WeakPolarHBondContact O-CA 3.36Å; F378-P380 HydrophobicContact CE1-CG 4.02Å; F378-P380 HydrophobicContact CE2-CB 3.91Å; F378-P380 HydrophobicContact CE2-CG 3.94Å; F378-P380 HydrophobicContact CZ-CB 4Å; F378-P380 HydrophobicContact CZ-CG 3.57Å; P380-K382 HydrophobicContact CB-CG 4.12Å; P380-D390 HydrophobicContact CG-CB 4.12Å; P380-D390 WeakPolarHBondContact CG-OD1 3.32Å; P380-D390 CarbonylContact O-C 3.52Å; P380-D390 VanDerWaalsContact O-C 3.3Å; P380-D390 WeakPolarHBondContact O-CA 3.32Å; P380-D390 VanDerWaalsContact O-CB 3.24Å; P380-D390 WeakPolarHBondContact O-CB 3.25Å; P380-C395 PolarHBondContact O-SG 3.47Å
381L95.3Very high94.1Very high0 Ų046.5 Ų46.50%025%0.25CS..  trans-102.594.6174.7-177.167.2000109.7L91 K97 Y100 V102 L110 D229 P392L91-L381 HydrophobicContact CD1-CD2 3.77Å; L91-L381 HydrophobicContact CD1-CG 3.88Å; L91-L381 HydrophobicContact CD2-CD1 3.94Å; L91-L381 HydrophobicContact CD2-CG 3.98Å; K97-L381 PolarHBondContact NZ-O 3.14Å; Y100-L381 HydrophobicContact CD1-CD2 3.6Å; Y100-L381 HydrophobicContact CE1-CD2 4.22Å; Y100-L381 HydrophobicContact CG-CD2 3.87Å; V102-L381 HydrophobicContact CG1-CD1 4.36Å; V102-L381 HydrophobicContact CG1-CD2 3.96Å; L110-L381 HydrophobicContact CD1-CD2 3.93Å; D229-L381 HydrophobicContact CB-CB 4.46Å; D229-L381 WeakPolarHBondContact CB-O 3.42Å; D229-L381 PolarHBondContact O-N 3.45Å; L381-P392 HydrophobicContact CD1-CB 4.49Å; L381-P392 HydrophobicContact CD1-CG 3.94Å
382K91.7Very high94.2Very high70 Ų7045.8 Ų45.830%0.30425%0.247SC..  trans-116.8-33.7-174.6-58.4-65.1-176.3175.20113.1R90 D229 P380 D390R90-K382 WeakPolarHBondContact CB-O 3.4Å; D229-K382 IonicContact OD1-NZ 3.74Å; D229-K382 PolarHBondContact OD1-NZ 3.48Å; D229-K382 WeakPolarHBondContact OD2-CD 3.17Å; D229-K382 WeakPolarHBondContact OD2-CE 3.35Å; D229-K382 IonicContact OD2-NZ 2.77Å; D229-K382 PolarHBondContact OD2-NZ 2.74Å; P380-K382 HydrophobicContact CB-CG 4.12Å; K382-D390 HydrophobicContact CB-CB 4.11Å; K382-D390 HydrophobicContact CG-CB 4.24Å; K382-D390 PolarHBondContact N-O 2.92Å
383N92.5Very high94.3Very high46 Ų4648.6 Ų48.625%0.24627%0.265CS..SBendtrans-126.8157.3-167-51.7-52.3000111.8L91 A387 V389 D390 C391 P392L91-N383 VanDerWaalsContact CD2-C 3.46Å; L91-N383 WeakPolarHBondContact CD2-O 3.44Å; N383-A387 HydrophobicContact CB-CB 3.49Å; N383-A387 VanDerWaalsContact CB-CB 3.49Å; N383-V389 PolarHBondContact ND2-O 2.85Å; N383-V389 VanDerWaalsContact ND2-O 3.15Å; N383-D390 PolarHBondContact N-O 3.25Å; N383-C391 VanDerWaalsContact O-CA 3.25Å; N383-C391 WeakPolarHBondContact O-CA 3.44Å; N383-C391 WeakPolarHBondContact O-CB 3.04Å; N383-P392 WeakPolarHBondContact O-CD 3.16Å
384A91.7Very high94.4Very high32 Ų3247.3 Ų47.326%0.26426%0.258SS..  trans-65.7162.816700000111.4R90 S386 A387 C391R90-A384 PolarHBondContact O-N 3.13Å; A384-S386 PolarHBondContact O-N 2.88Å; A384-A387 WeakPolarHBondContact O-CB 3.21Å; A384-A387 PolarHBondContact O-N 2.97Å; A384-C391 WeakPolarHBondContact O-CB 3.25Å
385D93.7Very high94.5Very high69 Ų6945.3 Ų45.337%0.36925%0.25SS..G310 helixtrans-58.2-23.3-178.3-81.8-53.8000114.4A387 K388 C391 T393D385-A387 PolarHBondContact O-N 2.88Å; D385-A387 VanDerWaalsContact O-N 3.14Å; D385-K388 PolarHBondContact O-N 3.46Å; D385-C391 PolarHBondContact OD1-SG 2.89Å; D385-T393 VanDerWaalsContact CG-OG1 3.31Å; D385-T393 WeakPolarHBondContact OD1-CB 3.34Å; D385-T393 PolarHBondContact OD1-N 3.28Å; D385-T393 PolarHBondContact OD1-OG1 3.15Å
386S92.2Very high94.6Very high111 Ų11142.2 Ų42.278%0.77623%0.233SC*.G310 helixtrans-58.1-25.1173.855.20000113.5A384A384-S386 PolarHBondContact O-N 2.88Å
387A90Very high94.6Very high48 Ų4845.4 Ų45.440%0.39724%0.243SC..G310 helixtrans-79.7-15.4176.900000113.8N383 A384 D385 V389N383-A387 HydrophobicContact CB-CB 3.49Å; N383-A387 VanDerWaalsContact CB-CB 3.49Å; A384-A387 WeakPolarHBondContact O-CB 3.21Å; A384-A387 PolarHBondContact O-N 2.97Å; D385-A387 PolarHBondContact O-N 2.88Å; D385-A387 VanDerWaalsContact O-N 3.14Å; A387-V389 PolarHBondContact O-N 3.4Å
388K90.6Very high94.6Very high170 Ų17047 Ų4774%0.73925%0.252SS*.SBendtrans59.8-7.6-178.1-54.7-179.4178.6-179.40116.8D385D385-K388 PolarHBondContact O-N 3.46Å
389V90.5Very high94.6Very high86 Ų8645.9 Ų45.952%0.52125%0.247SC..SBendtrans-133141.4-178-1770000108.7N383 A387 C391N383-V389 PolarHBondContact ND2-O 2.85Å; N383-V389 VanDerWaalsContact ND2-O 3.15Å; A387-V389 PolarHBondContact O-N 3.4Å; V389-C391 PolarHBondContact O-N 3.44Å
390D93.8Very high94.7Very high38 Ų3846.6 Ų46.620%0.20325%0.25CC..SBendtrans51.643.2-177.9-53.9-24.8000112.1P380 K382 N383 S394P380-D390 HydrophobicContact CG-CB 4.12Å; P380-D390 WeakPolarHBondContact CG-OD1 3.32Å; P380-D390 CarbonylContact O-C 3.52Å; P380-D390 VanDerWaalsContact O-C 3.3Å; P380-D390 WeakPolarHBondContact O-CA 3.32Å; P380-D390 VanDerWaalsContact O-CB 3.24Å; P380-D390 WeakPolarHBondContact O-CB 3.25Å; K382-D390 HydrophobicContact CB-CB 4.11Å; K382-D390 HydrophobicContact CG-CB 4.24Å; K382-D390 PolarHBondContact N-O 2.92Å; N383-D390 PolarHBondContact N-O 3.25Å; D390-S394 PolarHBondContact N-OG 3.16Å
391C95.3Very high94.7Very high1 Ų149.2 Ų49.21%0.00726%0.263CS..SBendtrans-126170-172.574.70000111.5N383 A384 D385 V389 T393 S394 C395N383-C391 VanDerWaalsContact O-CA 3.25Å; N383-C391 WeakPolarHBondContact O-CA 3.44Å; N383-C391 WeakPolarHBondContact O-CB 3.04Å; A384-C391 WeakPolarHBondContact O-CB 3.25Å; D385-C391 PolarHBondContact OD1-SG 2.89Å; V389-C391 PolarHBondContact O-N 3.44Å; C391-T393 PolarHBondContact O-N 3.33Å; C391-T393 VanDerWaalsContact O-N 3.17Å; C391-S394 PolarHBondContact N-OG 3.13Å; C391-S394 PolarHBondContact O-N 2.89Å; C391-S394 VanDerWaalsContact O-N 3.08Å; C391-S394 PolarHBondContact O-OG 3.13Å; C391-C395 WeakPolarHBondContact O-CB 3.39Å; C391-C395 PolarHBondContact O-N 3.29Å; C391-C395 PolarHBondContact O-SG 3.25Å
392P96.4Very high94.8Very high4 Ų449.4 Ų49.43%0.02626%0.264CS..Hα-helixtrans-51.6-42.4-178.7-2733.9000113.3Y100 V102 L381 N383 R396Y100-P392 HydrophobicContact CE1-CB 4.12Å; Y100-P392 HydrophobicContact CE1-CG 3.61Å; Y100-P392 VanDerWaalsContact OH-CG 3.28Å; Y100-P392 WeakPolarHBondContact OH-CG 3.38Å; V102-P392 HydrophobicContact CB-CB 4.33Å; L381-P392 HydrophobicContact CD1-CB 4.49Å; L381-P392 HydrophobicContact CD1-CG 3.94Å; N383-P392 WeakPolarHBondContact O-CD 3.16Å; P392-R396 VanDerWaalsContact O-CB 3.23Å; P392-R396 WeakPolarHBondContact O-CB 3.42Å; P392-R396 PolarHBondContact O-N 3.4Å
393T96.7Very high95.2Very high66 Ų6646.4 Ų46.441%0.40525%0.251SS..Hα-helixtrans-66-42.4178-61.70000113D385 C391 R396 R397D385-T393 VanDerWaalsContact CG-OG1 3.31Å; D385-T393 WeakPolarHBondContact OD1-CB 3.34Å; D385-T393 PolarHBondContact OD1-N 3.28Å; D385-T393 PolarHBondContact OD1-OG1 3.15Å; C391-T393 PolarHBondContact O-N 3.33Å; C391-T393 VanDerWaalsContact O-N 3.17Å; T393-R396 PolarHBondContact OG1-NH2 3.36Å; T393-R397 WeakPolarHBondContact O-CB 3.36Å; T393-R397 PolarHBondContact O-N 2.96Å
394S96.1Very high95.3Very high5 Ų547.3 Ų47.34%0.03525%0.251CS..Hα-helixtrans-68.6-43.4177.566.80000111.1D390 C391 R396 R397 D398D390-S394 PolarHBondContact N-OG 3.16Å; C391-S394 PolarHBondContact N-OG 3.13Å; C391-S394 PolarHBondContact O-N 2.89Å; C391-S394 VanDerWaalsContact O-N 3.08Å; C391-S394 PolarHBondContact O-OG 3.13Å; S394-R396 PolarHBondContact O-N 2.68Å; S394-R397 PolarHBondContact O-N 3.15Å; S394-D398 WeakPolarHBondContact O-CB 3.46Å; S394-D398 PolarHBondContact O-N 3.29Å
395C97.7Very high95.6Very high0 Ų048.7 Ų48.70%025%0.25CC..Hα-helixtrans-57.6-46.1175.6-710000112.4V102 I231 S379 P380 C391 D398 L399V102-C395 HydrophobicContact CG1-CB 4.37Å; I231-C395 HydrophobicContact CB-CB 4.44Å; I231-C395 HydrophobicContact CD1-CB 4.28Å; I231-C395 HydrophobicContact CG2-CB 3.88Å; S379-C395 WeakPolarHBondContact OG-CA 3.28Å; P380-C395 PolarHBondContact O-SG 3.47Å; C391-C395 WeakPolarHBondContact O-CB 3.39Å; C391-C395 PolarHBondContact O-N 3.29Å; C391-C395 PolarHBondContact O-SG 3.25Å; C395-D398 PolarHBondContact O-N 3.33Å; C395-L399 WeakPolarHBondContact O-CB 3.35Å; C395-L399 PolarHBondContact O-N 3Å
396R97.3Very high95.8Very high61 Ų6146.6 Ų46.623%0.2324%0.237CC..Hα-helixtrans-63.3-46.8178.1-179.8167.969.9-106.9-4.6111.7V102 G103 L104 P392 T393 S394 D398 L399 Y400V102-R396 HydrophobicContact CG2-CB 4.44Å; V102-R396 PolarHBondContact O-NH1 2.78Å; G103-R396 WeakPolarHBondContact O-CD 3.28Å; L104-R396 HydrophobicContact CD2-CB 4.47Å; L104-R396 HydrophobicContact CD2-CG 4Å; P392-R396 VanDerWaalsContact O-CB 3.23Å; P392-R396 WeakPolarHBondContact O-CB 3.42Å; P392-R396 PolarHBondContact O-N 3.4Å; T393-R396 PolarHBondContact OG1-NH2 3.36Å; S394-R396 PolarHBondContact O-N 2.68Å; R396-D398 PolarHBondContact O-N 3.23Å; R396-L399 PolarHBondContact O-N 3.11Å; R396-Y400 VanDerWaalsContact CD-OH 3.29Å; R396-Y400 WeakPolarHBondContact CD-OH 3.38Å; R396-Y400 HydrophobicContact CG-CD1 4.47Å; R396-Y400 HydrophobicContact CG-CD2 4.16Å; R396-Y400 HydrophobicContact CG-CE1 3.84Å; R396-Y400 HydrophobicContact CG-CE2 3.48Å; R396-Y400 VanDerWaalsContact CG-CE2 3.48Å; R396-Y400 WeakPolarHBondContact CG-OH 3.44Å; R396-Y400 WeakPolarHBondContact O-CD1 3.39Å; R396-Y400 PolarHBondContact O-N 2.9Å
397R96.8Very high96Very high114 Ų11441.3 Ų41.343%0.4320%0.2SC..Hα-helixtrans-57.9-47175.5178.3-159.965.2-157.8-3.7111.6T393 S394 L399 Y400 N401T393-R397 WeakPolarHBondContact O-CB 3.36Å; T393-R397 PolarHBondContact O-N 2.96Å; S394-R397 PolarHBondContact O-N 3.15Å; R397-L399 VanDerWaalsContact C-N 3.35Å; R397-L399 PolarHBondContact O-N 3.38Å; R397-Y400 PolarHBondContact O-N 3.13Å; R397-N401 PolarHBondContact O-N 3.15Å; R397-N401 PolarHBondContact O-ND2 3.2Å
398D97.6Very high96.3Very high35 Ų3540.4 Ų40.419%0.18719%0.187CC..Hα-helixtrans-66.9-39.1-176.3-59.8-15.6000111L232 S379 S394 C395 R396 N401 L402L232-D398 HydrophobicContact CD1-CB 4.3Å; S379-D398 WeakPolarHBondContact CB-OD2 3.3Å; S379-D398 PolarHBondContact OG-OD2 2.86Å; S394-D398 WeakPolarHBondContact O-CB 3.46Å; S394-D398 PolarHBondContact O-N 3.29Å; C395-D398 PolarHBondContact O-N 3.33Å; R396-D398 PolarHBondContact O-N 3.23Å; D398-N401 PolarHBondContact O-N 3.41Å; D398-L402 PolarHBondContact O-N 3.21Å
399L98.3Very high96.5Very high0 Ų036.4 Ų36.40%019%0.186CC..Hα-helixtrans-63.9-43.2172.9-169.975000111.9L104 I231 L232 C395 R396 R397 N401 L402 H403L104-L399 HydrophobicContact CD1-CD2 3.55Å; L104-L399 HydrophobicContact CD2-CD2 3.64Å; L104-L399 HydrophobicContact CG-CD2 4.26Å; I231-L399 HydrophobicContact CD1-CB 4.42Å; I231-L399 HydrophobicContact CD1-CD2 4.05Å; I231-L399 HydrophobicContact CG1-CD1 4.49Å; I231-L399 HydrophobicContact CG1-CD2 4.41Å; L232-L399 HydrophobicContact CD2-CB 4.2Å; L232-L399 HydrophobicContact CD2-CD1 3.68Å; C395-L399 WeakPolarHBondContact O-CB 3.35Å; C395-L399 PolarHBondContact O-N 3Å; R396-L399 PolarHBondContact O-N 3.11Å; R397-L399 VanDerWaalsContact C-N 3.35Å; R397-L399 PolarHBondContact O-N 3.38Å; L399-N401 VanDerWaalsContact C-N 3.32Å; L399-N401 PolarHBondContact O-N 3.46Å; L399-L402 PolarHBondContact O-N 2.84Å; L399-H403 WeakPolarHBondContact O-CB 3.18Å; L399-H403 PolarHBondContact O-N 2.86Å
400Y97.8Very high96.7Very high17 Ų1734.3 Ų34.37%0.06718%0.177CC..Hα-helixtrans-61.1-41.7175.6-65.9-13.3000112.1L104 P105 R396 R397 L402 H403 R404 V423 C424L104-Y400 HydrophobicContact CD2-CE1 3.84Å; P105-Y400 WeakPolarHBondContact CD-OH 3.33Å; R396-Y400 VanDerWaalsContact CD-OH 3.29Å; R396-Y400 WeakPolarHBondContact CD-OH 3.38Å; R396-Y400 HydrophobicContact CG-CD1 4.47Å; R396-Y400 HydrophobicContact CG-CD2 4.16Å; R396-Y400 HydrophobicContact CG-CE1 3.84Å; R396-Y400 HydrophobicContact CG-CE2 3.48Å; R396-Y400 VanDerWaalsContact CG-CE2 3.48Å; R396-Y400 WeakPolarHBondContact CG-OH 3.44Å; R396-Y400 WeakPolarHBondContact O-CD1 3.39Å; R396-Y400 PolarHBondContact O-N 2.9Å; R397-Y400 PolarHBondContact O-N 3.13Å; Y400-L402 PolarHBondContact O-N 3.26Å; Y400-H403 PolarHBondContact O-N 3.05Å; Y400-R404 WeakPolarHBondContact O-CB 3.5Å; Y400-R404 PolarHBondContact O-N 3.06Å; Y400-V423 HydrophobicContact CD2-CG2 4.39Å; Y400-V423 HydrophobicContact CE1-CG1 4.26Å; Y400-V423 HydrophobicContact CE2-CB 4.18Å; Y400-V423 HydrophobicContact CE2-CG1 4Å; Y400-V423 HydrophobicContact CE2-CG2 3.86Å; Y400-C424 WeakPolarHBondContact CA-O 3.44Å; Y400-C424 VanDerWaalsContact CD1-O 3.23Å; Y400-C424 WeakPolarHBondContact CD1-O 3.14Å
401N97Very high96.7Very high60 Ų6033.7 Ų33.732%0.32118%0.178SC..Hα-helixtrans-63.9-40.6177-74.7-22.4000112R397 D398 L399 R405R397-N401 PolarHBondContact O-N 3.15Å; R397-N401 PolarHBondContact O-ND2 3.2Å; D398-N401 PolarHBondContact O-N 3.41Å; L399-N401 VanDerWaalsContact C-N 3.32Å; L399-N401 PolarHBondContact O-N 3.46Å; N401-R405 WeakPolarHBondContact O-CG 3.48Å; N401-R405 PolarHBondContact O-N 3.14Å; N401-R405 VanDerWaalsContact O-N 3.11Å
402L98.1Very high96.6Very high5 Ų537 Ų373%0.02621%0.212CC..Hα-helixtrans-61.5-52.2174.6177.761.5000111.2L232 E376 D398 L399 Y400 R404 R405 W406L232-L402 HydrophobicContact CD2-CD2 3.89Å; E376-L402 HydrophobicContact CB-CD1 4.37Å; E376-L402 HydrophobicContact CG-CD1 4.07Å; D398-L402 PolarHBondContact O-N 3.21Å; L399-L402 PolarHBondContact O-N 2.84Å; Y400-L402 PolarHBondContact O-N 3.26Å; L402-R404 VanDerWaalsContact C-N 3.35Å; L402-R404 PolarHBondContact O-N 2.81Å; L402-R405 WeakPolarHBondContact O-CB 3.38Å; L402-R405 PolarHBondContact O-N 2.65Å; L402-W406 HydrophobicContact CD1-CZ2 3.83Å; L402-W406 HydrophobicContact CD2-CH2 4.09Å; L402-W406 HydrophobicContact CD2-CZ2 3.67Å; L402-W406 HydrophobicContact CG-CD2 4.37Å; L402-W406 HydrophobicContact CG-CH2 4.32Å; L402-W406 HydrophobicContact CG-CZ2 3.68Å; L402-W406 PolarHBondContact O-N 3Å; L402-W406 VanDerWaalsContact O-N 3.09Å
403H98.2Very high96.5Very high6 Ų641.4 Ų41.43%0.02823%0.228CC..Hα-helixtrans-65.3-36.9-178.8-69.9170.8000112.8L399 Y400 W406 V407 C424 E425 V426L399-H403 WeakPolarHBondContact O-CB 3.18Å; L399-H403 PolarHBondContact O-N 2.86Å; Y400-H403 PolarHBondContact O-N 3.05Å; H403-W406 AromaticContact CD2-CE3 3.59Å; H403-W406 AromaticContact CD2-CZ3 3.5Å; H403-W406 VanDerWaalsContact CD2-CZ3 3.5Å; H403-W406 WeakPolarHBondContact CD2-CZ3 3.32Å; H403-W406 AromaticContact NE2-CZ3 3.76Å; H403-W406 PolarHBondContact O-N 3.4Å; H403-V407 WeakPolarHBondContact O-CG2 3.49Å; H403-V407 PolarHBondContact O-N 2.92Å; H403-C424 HydrophobicContact CB-CB 4.36Å; H403-C424 WeakPolarHBondContact CB-O 3.49Å; H403-E425 WeakPolarHBondContact ND1-CA 3.37Å; H403-V426 HydrophobicContact CB-CB 4.4Å; H403-V426 HydrophobicContact CB-CG2 3.99Å; H403-V426 PolarHBondContact CE1-N 2.79Å; H403-V426 PolarHBondContact CE1-O 3.5Å; H403-V426 PolarHBondContact ND1-N 3.48Å
404R96.5Very high96.2Very high66 Ų6642.3 Ų42.325%0.24924%0.238CC..Hα-helixtrans-56-50.6170.7-176.4-174.96985.45.4110.5Y400 L402 W406 V407 E408 F415 I422 C424Y400-R404 WeakPolarHBondContact O-CB 3.5Å; Y400-R404 PolarHBondContact O-N 3.06Å; L402-R404 VanDerWaalsContact C-N 3.35Å; L402-R404 PolarHBondContact O-N 2.81Å; R404-W406 VanDerWaalsContact C-N 3.29Å; R404-W406 PolarHBondContact O-N 2.8Å; R404-V407 PolarHBondContact O-N 2.75Å; R404-E408 HydrophobicContact CG-CG 4.24Å; R404-E408 IonicContact CZ-OE1 3.1Å; R404-E408 IonicContact CZ-OE2 2.64Å; R404-E408 IonicContact NH1-OE1 4Å; R404-E408 PolarHBondContact NH1-OE1 2.99Å; R404-E408 IonicContact NH1-OE2 3.49Å; R404-E408 PolarHBondContact NH1-OE2 3.38Å; R404-E408 WeakPolarHBondContact O-CB 3.43Å; R404-E408 VanDerWaalsContact O-CG 3.3Å; R404-E408 WeakPolarHBondContact O-CG 3.37Å; R404-E408 PolarHBondContact O-N 3.38Å; R404-F415 HydrophobicContact CB-CE2 4.41Å; R404-F415 HydrophobicContact CG-CD2 3.59Å; R404-F415 HydrophobicContact CG-CE2 3.75Å; R404-F415 HydrophobicContact CG-CG 4.45Å; R404-I422 HydrophobicContact CG-CG2 4.39Å; R404-C424 HydrophobicContact CB-CB 4.23Å
405R96.2Very high96Very high61 Ų6142.7 Ų42.723%0.2324%0.238CC..Hα-helixtrans-59-39.9178.5-74-174.1-67.9133.2-8.7112.2E375 E376 N401 L402 A409E375-R405 PolarHBondContact O-NH2 3.03Å; E376-R405 IonicContact OE1-NH1 2.97Å; E376-R405 PolarHBondContact OE1-NH1 3.32Å; N401-R405 WeakPolarHBondContact O-CG 3.48Å; N401-R405 PolarHBondContact O-N 3.14Å; N401-R405 VanDerWaalsContact O-N 3.11Å; L402-R405 WeakPolarHBondContact O-CB 3.38Å; L402-R405 PolarHBondContact O-N 2.65Å; R405-A409 VanDerWaalsContact O-CB 3.25Å; R405-A409 WeakPolarHBondContact O-CB 3.49Å; R405-A409 PolarHBondContact O-N 3.33Å
406W97.7Very high95.3Very high25 Ų2550 Ų5010%0.09527%0.273CS..Hα-helixtrans-64.1-45.3176.4-63.3-12.7000112.5L402 H403 R404 A409 A410 V426 G434 I437L402-W406 HydrophobicContact CD1-CZ2 3.83Å; L402-W406 HydrophobicContact CD2-CH2 4.09Å; L402-W406 HydrophobicContact CD2-CZ2 3.67Å; L402-W406 HydrophobicContact CG-CD2 4.37Å; L402-W406 HydrophobicContact CG-CH2 4.32Å; L402-W406 HydrophobicContact CG-CZ2 3.68Å; L402-W406 PolarHBondContact O-N 3Å; L402-W406 VanDerWaalsContact O-N 3.09Å; H403-W406 AromaticContact CD2-CE3 3.59Å; H403-W406 AromaticContact CD2-CZ3 3.5Å; H403-W406 VanDerWaalsContact CD2-CZ3 3.5Å; H403-W406 WeakPolarHBondContact CD2-CZ3 3.32Å; H403-W406 AromaticContact NE2-CZ3 3.76Å; H403-W406 PolarHBondContact O-N 3.4Å; R404-W406 VanDerWaalsContact C-N 3.29Å; R404-W406 PolarHBondContact O-N 2.8Å; W406-A409 PolarHBondContact O-N 3.05Å; W406-A410 WeakPolarHBondContact O-CB 3.45Å; W406-A410 PolarHBondContact O-N 2.99Å; W406-V426 HydrophobicContact CE3-CB 4.38Å; W406-V426 HydrophobicContact CE3-CG1 4.5Å; W406-G434 VanDerWaalsContact CD2-CA 3.41Å; W406-I437 HydrophobicContact CB-CD1 3.62Å; W406-I437 HydrophobicContact CE3-CD1 4.48Å
407V97.4Very high94.1Very high0 Ų052.2 Ų52.20%030%0.304CS..Hα-helixtrans-64.2-44.8177.7163.80000111.7H403 R404 A409 A410 A411 F415 V426 I437 L439 L445 M449 L451H403-V407 WeakPolarHBondContact O-CG2 3.49Å; H403-V407 PolarHBondContact O-N 2.92Å; R404-V407 PolarHBondContact O-N 2.75Å; V407-A409 PolarHBondContact O-N 3.41Å; V407-A410 PolarHBondContact O-N 3.36Å; V407-A411 WeakPolarHBondContact O-CB 3.23Å; V407-A411 PolarHBondContact O-N 2.97Å; V407-F415 HydrophobicContact CB-CE2 3.99Å; V407-F415 HydrophobicContact CB-CZ 4.34Å; V407-F415 HydrophobicContact CG1-CE2 3.52Å; V407-F415 HydrophobicContact CG1-CZ 3.73Å; V407-V426 HydrophobicContact CG2-CG2 3.98Å; V407-I437 HydrophobicContact CG2-CG2 4.49Å; V407-L439 HydrophobicContact CG1-CD1 3.7Å; V407-L445 HydrophobicContact CG1-CD2 3.76Å; V407-M449 HydrophobicContact CG1-SD 3.83Å; V407-M449 HydrophobicContact CG2-SD 4.43Å; V407-L451 HydrophobicContact CG2-CD1 3.79Å
408E95.5Very high93Very high29 Ų2949.3 Ų49.314%0.13631%0.31CS..Hα-helixtrans-64.6-40.4178.7-68.4-180162.400111.8R404 A411 G412 R413 F415R404-E408 HydrophobicContact CG-CG 4.24Å; R404-E408 IonicContact CZ-OE1 3.1Å; R404-E408 IonicContact CZ-OE2 2.64Å; R404-E408 IonicContact NH1-OE1 4Å; R404-E408 PolarHBondContact NH1-OE1 2.99Å; R404-E408 IonicContact NH1-OE2 3.49Å; R404-E408 PolarHBondContact NH1-OE2 3.38Å; R404-E408 WeakPolarHBondContact O-CB 3.43Å; R404-E408 VanDerWaalsContact O-CG 3.3Å; R404-E408 WeakPolarHBondContact O-CG 3.37Å; R404-E408 PolarHBondContact O-N 3.38Å; E408-A411 PolarHBondContact O-N 3.03Å; E408-G412 WeakPolarHBondContact O-CA 3.49Å; E408-G412 PolarHBondContact O-N 3.3Å; E408-R413 VanDerWaalsContact CA-O 3.23Å; E408-R413 WeakPolarHBondContact CA-O 3.49Å; E408-R413 VanDerWaalsContact CB-O 3.31Å; E408-R413 WeakPolarHBondContact CB-O 3.49Å; E408-R413 WeakPolarHBondContact CG-O 3.44Å; E408-R413 PolarHBondContact O-N 3.31Å; E408-F415 HydrophobicContact CG-CD2 3.76Å; E408-F415 HydrophobicContact CG-CE2 4.17Å; E408-F415 PolarHBondContact OE1-N 2.89Å; E408-F415 VanDerWaalsContact OE1-N 3.17Å
409A95.2Very high91.5Very high85 Ų8556.7 Ų56.770%0.70235%0.349SS*.Hα-helixtrans-63.6-41.2174.700000112R405 W406 V407R405-A409 VanDerWaalsContact O-CB 3.25Å; R405-A409 WeakPolarHBondContact O-CB 3.49Å; R405-A409 PolarHBondContact O-N 3.33Å; W406-A409 PolarHBondContact O-N 3.05Å; V407-A409 PolarHBondContact O-N 3.41Å
410A95.6Very high90.6Very high42 Ų4260.9 Ų60.935%0.34738%0.379SS..Hα-helixtrans-69.4-36.2177.400000113W406 V407 I437W406-A410 WeakPolarHBondContact O-CB 3.45Å; W406-A410 PolarHBondContact O-N 2.99Å; V407-A410 PolarHBondContact O-N 3.36Å; A410-I437 HydrophobicContact CB-CB 3.8Å; A410-I437 HydrophobicContact CB-CG2 3.62Å; A410-I437 WeakPolarHBondContact CB-O 3.48Å
411A94.3Very high90Very high26 Ų2664.1 Ų64.122%0.21540%0.4CS..Hα-helixtrans-82.6-24179.900000113.6V407 E408 R413 L439 L445V407-A411 WeakPolarHBondContact O-CB 3.23Å; V407-A411 PolarHBondContact O-N 2.97Å; E408-A411 PolarHBondContact O-N 3.03Å; A411-R413 HydrophobicContact CB-CG 4.45Å; A411-R413 WeakPolarHBondContact O-CG 3.38Å; A411-R413 PolarHBondContact O-N 2.88Å; A411-L439 HydrophobicContact CB-CD1 4.25Å; A411-L445 HydrophobicContact CB-CD1 3.83Å; A411-L445 HydrophobicContact CB-CD2 4.31Å
412G93.1Very high89.8Confident71 Ų7162.8 Ų62.873%0.73239%0.393SS*.THydrogen-bonded Turntrans69.117.1-169.100000113.7E408E408-G412 WeakPolarHBondContact O-CA 3.49Å; E408-G412 PolarHBondContact O-N 3.3Å
413R93.1Very high89.6Confident95 Ų9564.2 Ų64.236%0.35840%0.402SS..SBendtrans-140.7159.7-177.6-32-171-96.7106.5-6.2110.1E408 A411 E441 T443 L445E408-R413 VanDerWaalsContact CA-O 3.23Å; E408-R413 WeakPolarHBondContact CA-O 3.49Å; E408-R413 VanDerWaalsContact CB-O 3.31Å; E408-R413 WeakPolarHBondContact CB-O 3.49Å; E408-R413 WeakPolarHBondContact CG-O 3.44Å; E408-R413 PolarHBondContact O-N 3.31Å; A411-R413 HydrophobicContact CB-CG 4.45Å; A411-R413 WeakPolarHBondContact O-CG 3.38Å; A411-R413 PolarHBondContact O-N 2.88Å; R413-E441 PolarHBondContact NE-O 2.83Å; R413-E441 PolarHBondContact NH2-O 3.48Å; R413-T443 PolarHBondContact NH2-O 3.36Å; R413-L445 HydrophobicContact CB-CD1 4.14Å
414S91.8Very high89.6Confident86 Ų8664 Ų6460%0.60140%0.4SS*.PPolyproline II helixtrans-92.7154.9174.5-59.70000112
415F91.7Very high89.6Confident12 Ų1261 Ų615%0.05339%0.389CS..PPolyproline II helixtrans-58.8149.4163.5-79.6-101.9000110.1R404 V407 E408 A417 I422 C424 L445 M449R404-F415 HydrophobicContact CB-CE2 4.41Å; R404-F415 HydrophobicContact CG-CD2 3.59Å; R404-F415 HydrophobicContact CG-CE2 3.75Å; R404-F415 HydrophobicContact CG-CG 4.45Å; V407-F415 HydrophobicContact CB-CE2 3.99Å; V407-F415 HydrophobicContact CB-CZ 4.34Å; V407-F415 HydrophobicContact CG1-CE2 3.52Å; V407-F415 HydrophobicContact CG1-CZ 3.73Å; E408-F415 HydrophobicContact CG-CD2 3.76Å; E408-F415 HydrophobicContact CG-CE2 4.17Å; E408-F415 PolarHBondContact OE1-N 2.89Å; E408-F415 VanDerWaalsContact OE1-N 3.17Å; F415-A417 PolarHBondContact O-N 3.49Å; F415-I422 HydrophobicContact CB-CD1 3.53Å; F415-I422 HydrophobicContact CB-CG1 4.34Å; F415-I422 HydrophobicContact CD1-CG2 3.67Å; F415-I422 HydrophobicContact CD2-CG2 4.41Å; F415-I422 HydrophobicContact CE1-CG2 3.86Å; F415-I422 HydrophobicContact CG-CD1 4.08Å; F415-I422 HydrophobicContact CG-CG2 3.96Å; F415-I422 HydrophobicContact CZ-CG2 4.31Å; F415-C424 HydrophobicContact CZ-CB 4.2Å; F415-L445 HydrophobicContact CD1-CB 4.07Å; F415-L445 WeakPolarHBondContact CD1-O 3.38Å; F415-L445 HydrophobicContact CD2-CB 4.43Å; F415-L445 HydrophobicContact CE1-CB 4.33Å; F415-L445 HydrophobicContact CG-CB 4.13Å; F415-M449 HydrophobicContact CE1-CB 3.95Å; F415-M449 HydrophobicContact CE1-SD 4.21Å; F415-M449 HydrophobicContact CZ-CB 4.12Å; F415-M449 HydrophobicContact CZ-SD 3.84Å
416E83.1Confident89.7Confident154 Ų15458 Ų5872%0.7238%0.378SS*.PPolyproline II helixtrans-61.5129.2173.5-66.6-177179.700110.2G418E416-G418 PolarHBondContact O-N 3.05Å
417A71.3Confident89.8Confident108 Ų10857 Ų5789%0.89338%0.375SS*.PPolyproline II helixtrans-67.3121.8178.900000109.7F415F415-A417 PolarHBondContact O-N 3.49Å
418G72.8Confident89.8Confident53 Ų5357.3 Ų57.355%0.54638%0.377SS..  trans-132.6167.6170.400000111.1E416 S420E416-G418 PolarHBondContact O-N 3.05Å; G418-S420 PolarHBondContact O-N 3.19Å
419D67.9Low89.9Confident189 Ų18958 Ų58100%1.01138%0.381SS*.SBendtrans-67.8-3-176.4-67.1-26.5000114.4
420S78.4Confident90Very high89 Ų8955.9 Ų55.962%0.62236%0.358SS*.SBendtrans-119.1158.1-171.867.80000112.9G418 I422G418-S420 PolarHBondContact O-N 3.19Å; S420-I422 PolarHBondContact O-N 3.45Å
421T84.4Confident90.1Very high84 Ų8454 Ų5452%0.51534%0.342SS..  trans-63.4123.9175.9-56.40000109.4V423T421-V423 PolarHBondContact O-N 2.91Å
422I92.9Very high90.3Very high32 Ų3253.3 Ų53.316%0.16433%0.334CS..  trans-63.2122.3176-67159.7000109R404 F415 S420 C424R404-I422 HydrophobicContact CG-CG2 4.39Å; F415-I422 HydrophobicContact CB-CD1 3.53Å; F415-I422 HydrophobicContact CB-CG1 4.34Å; F415-I422 HydrophobicContact CD1-CG2 3.67Å; F415-I422 HydrophobicContact CD2-CG2 4.41Å; F415-I422 HydrophobicContact CE1-CG2 3.86Å; F415-I422 HydrophobicContact CG-CD1 4.08Å; F415-I422 HydrophobicContact CG-CG2 3.96Å; F415-I422 HydrophobicContact CZ-CG2 4.31Å; S420-I422 PolarHBondContact O-N 3.45Å; I422-C424 HydrophobicContact CG2-CB 4.25Å; I422-C424 PolarHBondContact O-N 3.27Å
423V95.7Very high90.4Very high36 Ų3651.5 Ų51.522%0.21831%0.312CS..  trans-88.3105.8173176.50000107.2P105 Y400 T421 S447 P448 M449P105-V423 HydrophobicContact CG-CG1 3.75Å; Y400-V423 HydrophobicContact CD2-CG2 4.39Å; Y400-V423 HydrophobicContact CE1-CG1 4.26Å; Y400-V423 HydrophobicContact CE2-CB 4.18Å; Y400-V423 HydrophobicContact CE2-CG1 4Å; Y400-V423 HydrophobicContact CE2-CG2 3.86Å; T421-V423 PolarHBondContact O-N 2.91Å; V423-S447 PolarHBondContact N-OG 2.97Å; V423-P448 HydrophobicContact CB-CB 3.85Å; V423-P448 HydrophobicContact CG1-CB 3.73Å; V423-P448 CarbonylContact O-C 3.3Å; V423-P448 VanDerWaalsContact O-CA 3.31Å; V423-P448 WeakPolarHBondContact O-CA 3.46Å; V423-M449 PolarHBondContact O-N 2.8Å
424C96.8Very high90.6Very high0 Ų048.1 Ų48.10%031%0.307CS..EExtended strand (participates in β ladder)trans-129.3118.3176.8-173.60000109.6Y400 H403 R404 F415 I422 M449Y400-C424 WeakPolarHBondContact CA-O 3.44Å; Y400-C424 VanDerWaalsContact CD1-O 3.23Å; Y400-C424 WeakPolarHBondContact CD1-O 3.14Å; H403-C424 HydrophobicContact CB-CB 4.36Å; H403-C424 WeakPolarHBondContact CB-O 3.49Å; R404-C424 HydrophobicContact CB-CB 4.23Å; F415-C424 HydrophobicContact CZ-CB 4.2Å; I422-C424 HydrophobicContact CG2-CB 4.25Å; I422-C424 PolarHBondContact O-N 3.27Å; C424-M449 CarbonylContact C-O 3.51Å; C424-M449 VanDerWaalsContact CA-O 3.31Å; C424-M449 WeakPolarHBondContact CA-O 3.45Å
425E97.9Very high90.7Very high3 Ų346 Ų461%0.01429%0.287CS..EExtended strand (participates in β ladder)trans-123.4119.1176-172.8-178.6-165.300110.6P105 S106 H403 M449 V450 L451P105-E425 WeakPolarHBondContact CB-OE2 3.32Å; P105-E425 WeakPolarHBondContact CD-OE2 3.44Å; P105-E425 HydrophobicContact CG-CB 4.46Å; S106-E425 WeakPolarHBondContact CB-OE1 3.32Å; S106-E425 WeakPolarHBondContact CB-OE2 3.22Å; S106-E425 PolarHBondContact N-OE2 2.82Å; S106-E425 VanDerWaalsContact OG-CD 3.32Å; S106-E425 PolarHBondContact OG-OE1 2.95Å; S106-E425 PolarHBondContact OG-OE2 3.47Å; H403-E425 WeakPolarHBondContact ND1-CA 3.37Å; E425-M449 PolarHBondContact N-O 3.36Å; E425-V450 HydrophobicContact CB-CG1 4.35Å; E425-V450 HydrophobicContact CB-CG2 4.41Å; E425-V450 CarbonylContact O-C 3.56Å; E425-V450 VanDerWaalsContact O-CA 3.29Å; E425-V450 WeakPolarHBondContact O-CA 3.41Å; E425-L451 PolarHBondContact O-N 3.34Å
426V98.4Very high90.8Very high0 Ų050 Ų500%031%0.309CS..EExtended strand (participates in β ladder)trans-102.3126169.2-179.80000108H403 W406 V407 L430 I437 L451H403-V426 HydrophobicContact CB-CB 4.4Å; H403-V426 HydrophobicContact CB-CG2 3.99Å; H403-V426 PolarHBondContact CE1-N 2.79Å; H403-V426 PolarHBondContact CE1-O 3.5Å; H403-V426 PolarHBondContact ND1-N 3.48Å; W406-V426 HydrophobicContact CE3-CB 4.38Å; W406-V426 HydrophobicContact CE3-CG1 4.5Å; V407-V426 HydrophobicContact CG2-CG2 3.98Å; V426-L430 HydrophobicContact CG1-CD2 4.24Å; V426-I437 HydrophobicContact CG1-CD1 4.1Å; V426-I437 HydrophobicContact CG1-CG1 4.4Å; V426-I437 HydrophobicContact CG2-CD1 4.05Å; V426-L451 HydrophobicContact CG2-CB 4.43Å; V426-L451 HydrophobicContact CG2-CD1 4.21Å; V426-L451 HydrophobicContact CG2-CG 4.5Å
427S98Very high91.4Very high3 Ų343.3 Ų43.32%0.02128%0.278CS..  trans-62.9134177.1178.40000111.3K108 L429 L430 S431 L451 E456K108-S427 PolarHBondContact NZ-OG 3.37Å; K108-S427 VanDerWaalsContact NZ-OG 3.08Å; S427-L429 PolarHBondContact O-N 3.17Å; S427-L429 PolarHBondContact OG-N 3.49Å; S427-L430 WeakPolarHBondContact O-CB 3.39Å; S427-L430 PolarHBondContact O-N 3.24Å; S427-S431 PolarHBondContact O-N 3.43Å; S427-S431 VanDerWaalsContact O-N 3.11Å; S427-L451 WeakPolarHBondContact CB-O 3.24Å; S427-L451 PolarHBondContact N-O 2.74Å; S427-E456 WeakPolarHBondContact CB-OE2 3.24Å; S427-E456 PolarHBondContact OG-OE1 2.77Å; S427-E456 PolarHBondContact OG-OE2 2.99Å
428P97.9Very high92.4Very high6 Ų645.4 Ų45.44%0.03927%0.273CS..THydrogen-bonded Turntrans-63-20.2174.7-16.626.3000114.3L113 E116 R117 R120 L430 S431L113-P428 HydrophobicContact CD2-CG 3.79Å; E116-P428 HydrophobicContact CB-CB 3.79Å; E116-P428 HydrophobicContact CB-CG 4.26Å; E116-P428 WeakPolarHBondContact OE2-CD 3.09Å; R117-P428 HydrophobicContact CG-CB 3.73Å; R120-P428 WeakPolarHBondContact CB-O 3.47Å; R120-P428 WeakPolarHBondContact CG-O 3.04Å; P428-L430 VanDerWaalsContact C-N 3.3Å; P428-S431 WeakPolarHBondContact CA-O 3.49Å
429L97Very high93.3Very high45 Ų4544.4 Ų44.424%0.23626%0.255CS..THydrogen-bonded Turntrans-71.5-25.6171.4-70.4176.2000112.8E116 L119 S427 A453 E456E116-L429 HydrophobicContact CB-CD2 3.84Å; E116-L429 HydrophobicContact CB-CG 3.81Å; E116-L429 HydrophobicContact CG-CD1 4.1Å; E116-L429 HydrophobicContact CG-CD2 3.87Å; E116-L429 HydrophobicContact CG-CG 3.68Å; L119-L429 HydrophobicContact CB-CD2 3.86Å; L119-L429 HydrophobicContact CD1-CD2 3.86Å; S427-L429 PolarHBondContact O-N 3.17Å; S427-L429 PolarHBondContact OG-N 3.49Å; L429-A453 HydrophobicContact CB-CB 3.62Å; L429-E456 HydrophobicContact CD1-CG 3.83Å
430L97.4Very high94.2Very high40 Ų4037.6 Ų37.621%0.20923%0.229CC..THydrogen-bonded Turntrans-84.8-47.6178.2176.862.7000110.8R120 V426 S427 P428 L451 A453R120-L430 PolarHBondContact NE-O 2.88Å; R120-L430 PolarHBondContact NH2-O 3.24Å; V426-L430 HydrophobicContact CG1-CD2 4.24Å; S427-L430 WeakPolarHBondContact O-CB 3.39Å; S427-L430 PolarHBondContact O-N 3.24Å; P428-L430 VanDerWaalsContact C-N 3.3Å; L430-L451 HydrophobicContact CD2-CB 3.65Å; L430-A453 HydrophobicContact CB-CB 4.27Å
431S98.1Very high94.5Very high2 Ų242 Ų421%0.01424%0.24CC..  trans-142.3128.8-173.3-165.20000111.6S427 P428 G434 E435S427-S431 PolarHBondContact O-N 3.43Å; S427-S431 VanDerWaalsContact O-N 3.11Å; P428-S431 WeakPolarHBondContact CA-O 3.49Å; S431-G434 WeakPolarHBondContact OG-CA 3.31Å; S431-G434 PolarHBondContact OG-N 3.11Å; S431-E435 WeakPolarHBondContact CA-OE1 3.29Å; S431-E435 VanDerWaalsContact CB-O 3.29Å; S431-E435 WeakPolarHBondContact CB-O 3.5Å; S431-E435 PolarHBondContact OG-N 3.11Å; S431-E435 PolarHBondContact OG-O 2.94Å; S431-E435 PolarHBondContact OG-OE2 3.14Å
432Y97.8Very high94.5Very high11 Ų1146.9 Ų46.94%0.04326%0.257CS..SBendtrans-83.6-42.5177.1175.4-97.2000112.2R117 L121 R234 V235 D237 E435R117-Y432 HydrophobicContact CB-CD2 4.02Å; R117-Y432 HydrophobicContact CB-CE2 4.06Å; R117-Y432 HydrophobicContact CG-CD2 4.28Å; R117-Y432 HydrophobicContact CG-CE2 4.48Å; L121-Y432 HydrophobicContact CD1-CD2 4.03Å; L121-Y432 HydrophobicContact CD1-CE2 3.4Å; L121-Y432 HydrophobicContact CD2-CD1 3.95Å; L121-Y432 HydrophobicContact CD2-CD2 3.92Å; L121-Y432 HydrophobicContact CD2-CE1 3.98Å; L121-Y432 HydrophobicContact CD2-CE2 3.93Å; L121-Y432 HydrophobicContact CD2-CG 3.92Å; L121-Y432 HydrophobicContact CG-CD1 4.5Å; L121-Y432 HydrophobicContact CG-CD2 3.57Å; L121-Y432 HydrophobicContact CG-CE1 4.47Å; L121-Y432 HydrophobicContact CG-CE2 3.5Å; L121-Y432 VanDerWaalsContact CG-CE2 3.5Å; L121-Y432 HydrophobicContact CG-CG 4.08Å; R234-Y432 WeakPolarHBondContact CB-OH 3.4Å; R234-Y432 PolarHBondContact O-OH 3.04Å; V235-Y432 WeakPolarHBondContact O-CE2 3.29Å; V235-Y432 PolarHBondContact O-OH 3.09Å; D237-Y432 VanDerWaalsContact CA-OH 3.27Å; D237-Y432 WeakPolarHBondContact CA-OH 3.49Å; D237-Y432 PolarHBondContact N-OH 2.82Å; Y432-E435 VanDerWaalsContact N-CD 3.28Å; Y432-E435 PolarHBondContact N-OE1 3.47Å; Y432-E435 PolarHBondContact N-OE2 2.81Å
433A96.3Very high94.4Very high34 Ų3447.7 Ų47.728%0.28126%0.263SS..SBendtrans-145.632.4-174.300000112.7E435A433-E435 PolarHBondContact N-OE2 3.3Å
434G96.7Very high94.1Very high23 Ų2349.7 Ų49.724%0.23728%0.277CS..SBendtrans91.90.6179.800000114.5W406 S431W406-G434 VanDerWaalsContact CD2-CA 3.41Å; S431-G434 WeakPolarHBondContact OG-CA 3.31Å; S431-G434 PolarHBondContact OG-N 3.11Å
435E94.9Very high94Very high42 Ų4249.9 Ų49.920%0.19628%0.278CS..THydrogen-bonded Turntrans-72.8156.6174.784.7-65.3162.100112.4R120 M124 S431 Y432 A433 I437R120-E435 IonicContact CZ-OE1 3.6Å; R120-E435 IonicContact NE-OE1 3.76Å; R120-E435 PolarHBondContact NE-OE1 2.95Å; R120-E435 IonicContact NH2-OE1 3.55Å; M124-E435 HydrophobicContact CE-CG 3.85Å; M124-E435 HydrophobicContact SD-CG 4.27Å; S431-E435 WeakPolarHBondContact CA-OE1 3.29Å; S431-E435 VanDerWaalsContact CB-O 3.29Å; S431-E435 WeakPolarHBondContact CB-O 3.5Å; S431-E435 PolarHBondContact OG-N 3.11Å; S431-E435 PolarHBondContact OG-O 2.94Å; S431-E435 PolarHBondContact OG-OE2 3.14Å; Y432-E435 VanDerWaalsContact N-CD 3.28Å; Y432-E435 PolarHBondContact N-OE1 3.47Å; Y432-E435 PolarHBondContact N-OE2 2.81Å; A433-E435 PolarHBondContact N-OE2 3.3Å; E435-I437 PolarHBondContact O-N 3.4Å; E435-I437 VanDerWaalsContact O-N 3.08Å
436N92.6Very high93.7Very high96 Ų9655 Ų5551%0.51330%0.303SS..THydrogen-bonded Turntrans58.320.6171.6-63.1-37.5000115.5R120 I438R120-N436 PolarHBondContact NH2-ND2 3.04Å; N436-I438 PolarHBondContact O-N 2.9Å
437I96.2Very high93.4Very high14 Ų1457.6 Ų57.67%0.07232%0.322CS..  trans-79.6113.4164.7-60175.6000107W406 V407 A410 V426 E435 L439 L451W406-I437 HydrophobicContact CB-CD1 3.62Å; W406-I437 HydrophobicContact CE3-CD1 4.48Å; V407-I437 HydrophobicContact CG2-CG2 4.49Å; A410-I437 HydrophobicContact CB-CB 3.8Å; A410-I437 HydrophobicContact CB-CG2 3.62Å; A410-I437 WeakPolarHBondContact CB-O 3.48Å; V426-I437 HydrophobicContact CG1-CD1 4.1Å; V426-I437 HydrophobicContact CG1-CG1 4.4Å; V426-I437 HydrophobicContact CG2-CD1 4.05Å; E435-I437 PolarHBondContact O-N 3.4Å; E435-I437 VanDerWaalsContact O-N 3.08Å; I437-L439 HydrophobicContact CG2-CD1 4.11Å; I437-L439 HydrophobicContact CG2-CG 4.09Å; I437-L451 HydrophobicContact CG2-CD1 3.86Å
438I92.8Very high93.2Very high152 Ų15262.1 Ų62.178%0.77935%0.351SS*.  trans-119.4117.7179.3-56.9173.5000107.2N436N436-I438 PolarHBondContact O-N 2.9Å
439L91Very high93Very high32 Ų3262.8 Ų62.817%0.16835%0.354CS..  trans-123.4131.6178.5-61.7170.9000107.7V407 A411 I437 T443 L445 L451V407-L439 HydrophobicContact CG1-CD1 3.7Å; A411-L439 HydrophobicContact CB-CD1 4.25Å; I437-L439 HydrophobicContact CG2-CD1 4.11Å; I437-L439 HydrophobicContact CG2-CG 4.09Å; L439-T443 HydrophobicContact CD2-CG2 4.25Å; L439-L445 HydrophobicContact CD1-CD2 4.06Å; L439-L451 HydrophobicContact CD2-CD1 4.22Å; L439-L451 HydrophobicContact CD2-CD2 4.3Å
440G87Confident93Very high46 Ų4663 Ų6347%0.47436%0.357SS..  trans-65.5150.4172.900000110.4E442 T443G440-E442 PolarHBondContact O-N 3.21Å; G440-E442 VanDerWaalsContact O-N 3.11Å; G440-T443 WeakPolarHBondContact CA-OG1 3.44Å; G440-T443 PolarHBondContact N-OG1 2.86Å; G440-T443 VanDerWaalsContact O-CB 3.25Å; G440-T443 WeakPolarHBondContact O-CB 3.31Å; G440-T443 PolarHBondContact O-N 3.44Å; G440-T443 PolarHBondContact O-OG1 2.93Å
441E84.2Confident92.9Very high181 Ų18162.5 Ų62.585%0.84635%0.354SS*.THydrogen-bonded Turntrans-51.5-39.2-177.2-68.2-175.8170.400112.6R413R413-E441 PolarHBondContact NE-O 2.83Å; R413-E441 PolarHBondContact NH2-O 3.48Å
442E86Confident92.8Very high186 Ų18668.3 Ų68.387%0.86938%0.376SS*.THydrogen-bonded Turntrans-83-4.8-179.2-59.3-172166.700114.5G440 P444G440-E442 PolarHBondContact O-N 3.21Å; G440-E442 VanDerWaalsContact O-N 3.11Å; E442-P444 WeakPolarHBondContact O-CD 3.41Å; E442-P444 VanDerWaalsContact O-N 3.12Å
443T90.2Very high92.6Very high49 Ų4968.3 Ų68.330%0.30138%0.378SS..  trans-63.4114.2-176.3-50.90000110.1R413 L439 G440 L445 M449R413-T443 PolarHBondContact NH2-O 3.36Å; L439-T443 HydrophobicContact CD2-CG2 4.25Å; G440-T443 WeakPolarHBondContact CA-OG1 3.44Å; G440-T443 PolarHBondContact N-OG1 2.86Å; G440-T443 VanDerWaalsContact O-CB 3.25Å; G440-T443 WeakPolarHBondContact O-CB 3.31Å; G440-T443 PolarHBondContact O-N 3.44Å; G440-T443 PolarHBondContact O-OG1 2.93Å; T443-L445 PolarHBondContact O-N 2.73Å; T443-M449 HydrophobicContact CG2-CE 4.36Å
444P90Very high92.3Very high79 Ų7970.6 Ų70.651%0.51340%0.397SS..  trans-63.3131-177.3-23.435.5000111.5E442 M446 M449E442-P444 WeakPolarHBondContact O-CD 3.41Å; E442-P444 VanDerWaalsContact O-N 3.12Å; P444-M446 HydrophobicContact CB-CE 4.01Å; P444-M446 HydrophobicContact CB-CG 3.97Å; P444-M446 HydrophobicContact CB-SD 4.26Å; P444-M446 PolarHBondContact O-N 3.47Å; P444-M449 WeakPolarHBondContact O-CE 3.37Å
445L92.8Very high91.7Very high4 Ų473.8 Ų73.82%0.02142%0.421CS..  trans-92.381.3175.6-61-172.9000109.3V407 A411 R413 F415 L439 T443 M449V407-L445 HydrophobicContact CG1-CD2 3.76Å; A411-L445 HydrophobicContact CB-CD1 3.83Å; A411-L445 HydrophobicContact CB-CD2 4.31Å; R413-L445 HydrophobicContact CB-CD1 4.14Å; F415-L445 HydrophobicContact CD1-CB 4.07Å; F415-L445 WeakPolarHBondContact CD1-O 3.38Å; F415-L445 HydrophobicContact CD2-CB 4.43Å; F415-L445 HydrophobicContact CE1-CB 4.33Å; F415-L445 HydrophobicContact CG-CB 4.13Å; L439-L445 HydrophobicContact CD1-CD2 4.06Å; T443-L445 PolarHBondContact O-N 2.73Å; L445-M449 HydrophobicContact CD2-CE 4.05Å; L445-M449 HydrophobicContact CD2-SD 4.2Å
446M91.9Very high91.4Very high109 Ų10974 Ų7454%0.53742%0.422SS..  trans-117.3150-175.5-60.6-167.9-60.700112.1P444 P448 M449P444-M446 HydrophobicContact CB-CE 4.01Å; P444-M446 HydrophobicContact CB-CG 3.97Å; P444-M446 HydrophobicContact CB-SD 4.26Å; P444-M446 PolarHBondContact O-N 3.47Å; M446-P448 CarbonylContact O-C 2.99Å; M446-M449 WeakPolarHBondContact O-CB 3.05Å; M446-M449 PolarHBondContact O-N 2.73Å
447S92.8Very high90.9Very high55 Ų5575.5 Ų75.539%0.38543%0.429SS..SBendtrans-91.2134.7173.4-179.30000110.6V423V423-S447 PolarHBondContact N-OG 2.97Å
448P93.3Very high89.2Confident98 Ų9881 Ų8164%0.63649%0.49SS*.SBendcis-78.5139.6-532.4-34.1000112.6V423 M446V423-P448 HydrophobicContact CB-CB 3.85Å; V423-P448 HydrophobicContact CG1-CB 3.73Å; V423-P448 CarbonylContact O-C 3.3Å; V423-P448 VanDerWaalsContact O-CA 3.31Å; V423-P448 WeakPolarHBondContact O-CA 3.46Å; M446-P448 CarbonylContact O-C 2.99Å
449M94.9Very high89Confident20 Ų2077.5 Ų77.510%0.09948%0.475CS..EExtended strand (participates in β ladder)trans-112.6121.4169.7179.4165.9-99.900109.8V407 F415 V423 C424 E425 T443 P444 L445 M446 L451V407-M449 HydrophobicContact CG1-SD 3.83Å; V407-M449 HydrophobicContact CG2-SD 4.43Å; F415-M449 HydrophobicContact CE1-CB 3.95Å; F415-M449 HydrophobicContact CE1-SD 4.21Å; F415-M449 HydrophobicContact CZ-CB 4.12Å; F415-M449 HydrophobicContact CZ-SD 3.84Å; V423-M449 PolarHBondContact O-N 2.8Å; C424-M449 CarbonylContact C-O 3.51Å; C424-M449 VanDerWaalsContact CA-O 3.31Å; C424-M449 WeakPolarHBondContact CA-O 3.45Å; E425-M449 PolarHBondContact N-O 3.36Å; T443-M449 HydrophobicContact CG2-CE 4.36Å; P444-M449 WeakPolarHBondContact O-CE 3.37Å; L445-M449 HydrophobicContact CD2-CE 4.05Å; L445-M449 HydrophobicContact CD2-SD 4.2Å; M446-M449 WeakPolarHBondContact O-CB 3.05Å; M446-M449 PolarHBondContact O-N 2.73Å; M449-L451 HydrophobicContact CG-CD2 3.96Å; M449-L451 HydrophobicContact CG-CG 4.23Å; M449-L451 HydrophobicContact SD-CD2 4.25Å
450V96Very high88.9Confident50 Ų5079.8 Ų79.830%0.30349%0.492SS..EExtended strand (participates in β ladder)trans-124.7108.5177.9-175.60000108.8P105 E425 R452P105-V450 HydrophobicContact CB-CG2 3.68Å; P105-V450 HydrophobicContact CG-CG2 3.99Å; E425-V450 HydrophobicContact CB-CG1 4.35Å; E425-V450 HydrophobicContact CB-CG2 4.41Å; E425-V450 CarbonylContact O-C 3.56Å; E425-V450 VanDerWaalsContact O-CA 3.29Å; E425-V450 WeakPolarHBondContact O-CA 3.41Å; V450-R452 HydrophobicContact CG1-CG 4.17Å
451L96.5Very high89Confident30 Ų3081.7 Ų81.716%0.15749%0.493CS..EExtended strand (participates in β ladder)trans-94.7119.5177.4-55.7-172.3000109.6V407 E425 V426 S427 L430 I437 L439 M449V407-L451 HydrophobicContact CG2-CD1 3.79Å; E425-L451 PolarHBondContact O-N 3.34Å; V426-L451 HydrophobicContact CG2-CB 4.43Å; V426-L451 HydrophobicContact CG2-CD1 4.21Å; V426-L451 HydrophobicContact CG2-CG 4.5Å; S427-L451 WeakPolarHBondContact CB-O 3.24Å; S427-L451 PolarHBondContact N-O 2.74Å; L430-L451 HydrophobicContact CD2-CB 3.65Å; I437-L451 HydrophobicContact CG2-CD1 3.86Å; L439-L451 HydrophobicContact CD2-CD1 4.22Å; L439-L451 HydrophobicContact CD2-CD2 4.3Å; M449-L451 HydrophobicContact CG-CD2 3.96Å; M449-L451 HydrophobicContact CG-CG 4.23Å; M449-L451 HydrophobicContact SD-CD2 4.25Å
452R95.5Very high89.3Confident124 Ų12475.9 Ų75.947%0.46847%0.472SS..  trans-110.5149.8-179.3-63.9-175.5-178.4179.80.4110.6V450 E456 L457V450-R452 HydrophobicContact CG1-CG 4.17Å; R452-E456 HydrophobicContact CB-CB 4.17Å; R452-L457 HydrophobicContact CB-CD2 4.09Å
453A93.6Very high89.5Confident10 Ų1069 Ų698%0.08345%0.447CS..  trans-69.2153.2166.500000109.8L429 L430 A455 E456L429-A453 HydrophobicContact CB-CB 3.62Å; L430-A453 HydrophobicContact CB-CB 4.27Å; A453-A455 PolarHBondContact O-N 2.86Å; A453-A455 VanDerWaalsContact O-N 3.16Å; A453-E456 HydrophobicContact CB-CG 4.45Å; A453-E456 WeakPolarHBondContact CB-OE2 3.23Å; A453-E456 PolarHBondContact N-OE2 2.81Å; A453-E456 WeakPolarHBondContact O-CB 3.49Å; A453-E456 PolarHBondContact O-N 3.23Å
454A88.5Confident89.5Confident83 Ų8370.3 Ų70.369%0.68646%0.457SS*.G310 helixtrans-55-36.3178.600000112.5E456 L457A454-E456 PolarHBondContact O-N 3.16Å; A454-E456 VanDerWaalsContact O-N 3.09Å; A454-L457 PolarHBondContact O-N 3.35Å; A454-L457 VanDerWaalsContact O-N 3.16Å
455A85.2Confident89.4Confident90 Ų9069.7 Ų69.774%0.74445%0.453SS*.G310 helixtrans-63.3-12.1177.400000114.7A453A453-A455 PolarHBondContact O-N 2.86Å; A453-A455 VanDerWaalsContact O-N 3.16Å
456E88.2Confident89.2Confident46 Ų4674.8 Ų74.822%0.21549%0.486CS..G310 helixtrans-100-1.6179.4-61.3174.492.200113.3K108 S427 L429 R452 A453 A454K108-E456 WeakPolarHBondContact CE-OE1 3.45Å; K108-E456 IonicContact NZ-OE1 2.76Å; K108-E456 PolarHBondContact NZ-OE1 2.46Å; S427-E456 WeakPolarHBondContact CB-OE2 3.24Å; S427-E456 PolarHBondContact OG-OE1 2.77Å; S427-E456 PolarHBondContact OG-OE2 2.99Å; L429-E456 HydrophobicContact CD1-CG 3.83Å; R452-E456 HydrophobicContact CB-CB 4.17Å; A453-E456 HydrophobicContact CB-CG 4.45Å; A453-E456 WeakPolarHBondContact CB-OE2 3.23Å; A453-E456 PolarHBondContact N-OE2 2.81Å; A453-E456 WeakPolarHBondContact O-CB 3.49Å; A453-E456 PolarHBondContact O-N 3.23Å; A454-E456 PolarHBondContact O-N 3.16Å; A454-E456 VanDerWaalsContact O-N 3.09Å
457L81.8Confident88.9Confident127 Ų12771.9 Ų71.967%0.66548%0.482SS*.  trans-92.35-174.9-63.2178.2000113.8R452 A454R452-L457 HydrophobicContact CB-CD2 4.09Å; A454-L457 PolarHBondContact O-N 3.35Å; A454-L457 VanDerWaalsContact O-N 3.16Å
458G61Low88.6Confident130 Ų13073.5 Ų73.5100%1.3449%0.49SS*.  trans85.80-168.800000111.6

Retrieved 458 of 458 residues in 169.4 ms (Link to these results)