A0A077Z078_TRITR Loading...

Bestrophin domain containing protein

AlphaFold DB , UniProt , Accession A0A077Z078, Species TRITR (Trichuris trichiura, Whipworm), Gene n/a, Length 788 aa.

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Site Residue pLDDT pLDDT confidence pLDDT10 pLDDT10 confidence SASA SASA [Ų] SASA10 SASA10 [Ų] RSA RSA unformatted RSA10 RSA10 unformatted Surface Surface10 (not used) Disorder (not used) Disorder Sec. str. Secondary structure Isomer Phi (φ) Psi (ψ) Omega (ω) Chi 1 (χ1) Chi 2 (χ2) Chi 3 (χ3) Chi 4 (χ4) Chi 5 (χ5) Tau (τ) Contacts (colored by PAE) Contact details
1M54.3Low66Low176 Ų17654.6 Ų54.687%0.86728%0.28SS*.  0130.50-84.6-162.4-86.500107.3I3 E306M1-I3 PolarHBondContact O-N 2.79Å; M1-E306 VanDerWaalsContact C-OE1 3.27Å; M1-E306 WeakPolarHBondContact CA-OE1 3.47Å; M1-E306 WeakPolarHBondContact CB-OE1 3.16Å; M1-E306 VanDerWaalsContact CG-OE1 3.3Å; M1-E306 WeakPolarHBondContact CG-OE1 3.36Å
2T65Low66.2Low20 Ų2052.1 Ų52.112%0.12327%0.268CS..  trans-58.8130.6178.7-52.60000109.3S4 D304 E306T2-S4 PolarHBondContact O-N 3.04Å; T2-D304 PolarHBondContact OG1-O 3.3Å; T2-D304 VanDerWaalsContact OG1-O 3.11Å; T2-E306 PolarHBondContact N-OE1 2.91Å
3I65.6Low66.8Low17 Ų1751.4 Ų51.49%0.08727%0.271CS..  trans-90.597.2-173.1-58.1-176.1000109.8M1 R23 R25 D302 L611M1-I3 PolarHBondContact O-N 2.79Å; I3-R23 VanDerWaalsContact CG2-NH1 3.27Å; I3-R25 HydrophobicContact CD1-CB 3.35Å; I3-R25 WeakPolarHBondContact CD1-O 3.48Å; I3-D302 HydrophobicContact CD1-CB 4.15Å; I3-L611 HydrophobicContact CG2-CD2 4.4Å
4S70.8Confident67.2Low50 Ų5052.8 Ų52.835%0.3528%0.278SS..  trans-72.1132.2172.8-175.30000111.3T2 R23T2-S4 PolarHBondContact O-N 3.04Å; S4-R23 PolarHBondContact O-NH1 2.94Å; S4-R23 PolarHBondContact O-NH2 3.34Å
5Y74.6Confident67.6Low2 Ų250 Ų501%0.00827%0.267CS..  trans-131.34.4172.165-90000112.5K7 E8 L20 P608 V609 L611 T614 L668Y5-K7 PolarHBondContact O-N 3.42Å; Y5-K7 VanDerWaalsContact O-N 3.15Å; Y5-E8 WeakPolarHBondContact O-CB 3.47Å; Y5-E8 PolarHBondContact O-N 2.93Å; Y5-L20 HydrophobicContact CD2-CD1 3.82Å; Y5-L20 HydrophobicContact CD2-CD2 3.94Å; Y5-L20 HydrophobicContact CE2-CD1 4.04Å; Y5-L20 HydrophobicContact CG-CD2 4.06Å; Y5-P608 HydrophobicContact CD1-CG 4.17Å; Y5-P608 HydrophobicContact CE1-CB 4.1Å; Y5-P608 HydrophobicContact CE1-CG 4Å; Y5-V609 WeakPolarHBondContact CE1-O 3.37Å; Y5-V609 VanDerWaalsContact CZ-O 3.29Å; Y5-V609 PolarHBondContact OH-O 2.96Å; Y5-L611 HydrophobicContact CD1-CB 4.14Å; Y5-L611 HydrophobicContact CD1-CD1 4.04Å; Y5-L611 HydrophobicContact CE1-CB 4Å; Y5-L611 HydrophobicContact CE1-CD1 4.22Å; Y5-L611 HydrophobicContact CG-CD1 4.29Å; Y5-T614 PolarHBondContact OH-OG1 3.44Å; Y5-L668 HydrophobicContact CD2-CD2 4.27Å; Y5-L668 HydrophobicContact CE2-CD1 4Å; Y5-L668 HydrophobicContact CE2-CD2 3.51Å; Y5-L668 HydrophobicContact CE2-CG 4.42Å
6T68.7Low68.2Low9 Ų947.4 Ų47.46%0.05525%0.253CS..G310 helixtrans-52.3-43-176-47.20000111.7E8 C9 A10 D605 N669T6-E8 VanDerWaalsContact C-N 3.28Å; T6-E8 PolarHBondContact O-N 3.46Å; T6-C9 CarbonylContact O-C 3.56Å; T6-C9 PolarHBondContact O-N 3.19Å; T6-A10 PolarHBondContact O-N 2.7Å; T6-D605 WeakPolarHBondContact CG2-OD1 3.17Å; T6-N669 HydrophobicContact CG2-CB 3.94Å; T6-N669 PolarHBondContact O-ND2 3.04Å
7K70.8Confident68.7Low176 Ų17644.7 Ų44.777%0.76524%0.239SC*.G310 helixtrans-56.7-36.1175.9176.5-177.8171.8-173.60113.8Y5 C9 A10Y5-K7 PolarHBondContact O-N 3.42Å; Y5-K7 VanDerWaalsContact O-N 3.15Å; K7-C9 PolarHBondContact O-N 2.68Å; K7-A10 VanDerWaalsContact O-CB 3.32Å; K7-A10 WeakPolarHBondContact O-CB 3.35Å; K7-A10 PolarHBondContact O-N 3.15Å
8E68.2Low69.3Low84 Ų8445.3 Ų45.339%0.39324%0.242SC..G310 helixtrans-71.8-17.7-179.5-63.6171.6-165.600111.9Y5 T6 L20 R23Y5-E8 WeakPolarHBondContact O-CB 3.47Å; Y5-E8 PolarHBondContact O-N 2.93Å; T6-E8 VanDerWaalsContact C-N 3.28Å; T6-E8 PolarHBondContact O-N 3.46Å; E8-L20 HydrophobicContact CB-CD2 4.44Å; E8-L20 WeakPolarHBondContact OE2-CD2 3.31Å; E8-R23 IonicContact OE1-NH1 2.79Å
9C63Low70Confident1 Ų151.7 Ų51.71%0.00726%0.262CS..G310 helixtrans-99.911175.9-60.30000113.4T6 K7 T11 L668 N669T6-C9 CarbonylContact O-C 3.56Å; T6-C9 PolarHBondContact O-N 3.19Å; K7-C9 PolarHBondContact O-N 2.68Å; C9-T11 PolarHBondContact O-N 3.44Å; C9-L668 HydrophobicContact CB-CD2 4.13Å; C9-N669 HydrophobicContact CB-CB 4.03Å
10A56.1Low70.5Confident8 Ų849.2 Ų49.27%0.06625%0.249CC..SBendtrans-69.8-13.9-176.500000115.2T6 K7 T518 N669 G672 E673T6-A10 PolarHBondContact O-N 2.7Å; K7-A10 VanDerWaalsContact O-CB 3.32Å; K7-A10 WeakPolarHBondContact O-CB 3.35Å; K7-A10 PolarHBondContact O-N 3.15Å; A10-T518 HydrophobicContact CB-CG2 3.68Å; A10-N669 VanDerWaalsContact CA-ND2 3.27Å; A10-N669 WeakPolarHBondContact CA-ND2 3.09Å; A10-N669 PolarHBondContact N-ND2 3.06Å; A10-G672 CarbonylContact O-C 3.26Å; A10-G672 WeakPolarHBondContact O-CA 3.39Å; A10-E673 PolarHBondContact O-N 3.4Å
11T68.7Low71.1Confident58 Ų5847.7 Ų47.736%0.35624%0.242SC..SBendtrans-140.3146.5164.950.60000108.7C9 S13 N16 E673 D674C9-T11 PolarHBondContact O-N 3.44Å; T11-S13 PolarHBondContact O-N 3.22Å; T11-N16 PolarHBondContact O-ND2 3.48Å; T11-E673 HydrophobicContact CG2-CB 3.88Å; T11-D674 WeakPolarHBondContact CA-OD2 3.24Å
12V69.1Low72.5Confident24 Ų2448 Ų4815%0.14524%0.238CC..  trans-80.6100.1169.8177.60000109.1I404 K662 Q665 V666 D674V12-I404 HydrophobicContact CG1-CB 4.18Å; V12-I404 HydrophobicContact CG1-CG2 4.41Å; V12-K662 HydrophobicContact CG1-CD 3.8Å; V12-Q665 HydrophobicContact CG2-CB 4.24Å; V12-Q665 HydrophobicContact CG2-CG 3.81Å; V12-V666 HydrophobicContact CB-CG2 4.3Å; V12-V666 HydrophobicContact CG2-CB 4.18Å; V12-V666 HydrophobicContact CG2-CG2 3.34Å; V12-D674 WeakPolarHBondContact CG2-OD2 3.36Å; V12-D674 PolarHBondContact N-OD1 2.82Å; V12-D674 PolarHBondContact N-OD2 3.01Å
13S73.2Confident73.4Confident43 Ų4350.6 Ų50.630%0.30125%0.246SC..  trans-119.7162.9168.4610000112.7T11 G15 N16T11-S13 PolarHBondContact O-N 3.22Å; S13-G15 PolarHBondContact O-N 3.31Å; S13-N16 PolarHBondContact N-ND2 2.89Å; S13-N16 PolarHBondContact O-N 3.21Å; S13-N16 PolarHBondContact OG-ND2 3.01Å; S13-N16 PolarHBondContact OG-OD1 2.59Å
14L72.6Confident74.3Confident71 Ų7156.5 Ų56.537%0.37227%0.268SS..THydrogen-bonded Turntrans-52.4123.6173.7-177.775.3000109.8K407 D408 I411L14-K407 HydrophobicContact CB-CD 4.44Å; L14-K407 HydrophobicContact CD1-CB 4.14Å; L14-D408 HydrophobicContact CD1-CB 4.36Å; L14-I411 HydrophobicContact CD1-CD1 3.64Å; L14-I411 HydrophobicContact CD2-CD1 3.37Å; L14-I411 HydrophobicContact CG-CD1 4.11Å
15G73.2Confident74.9Confident11 Ų1162.5 Ų62.511%0.11328%0.282CS..THydrogen-bonded Turntrans826.2172.200000117.5S13 L18 R19S13-G15 PolarHBondContact O-N 3.31Å; G15-L18 CarbonylContact O-C 3.31Å; G15-L18 WeakPolarHBondContact O-CB 3.34Å; G15-L18 PolarHBondContact O-N 2.81Å; G15-R19 WeakPolarHBondContact O-CG 3.4Å; G15-R19 PolarHBondContact O-N 3.45Å
16N76.7Confident75Confident8 Ų862.4 Ų62.44%0.04328%0.282CS..Hα-helixtrans-63.6-47179-71.5-3.4000112.8T11 S13 L18 R19 L20T11-N16 PolarHBondContact O-ND2 3.48Å; S13-N16 PolarHBondContact N-ND2 2.89Å; S13-N16 PolarHBondContact O-N 3.21Å; S13-N16 PolarHBondContact OG-ND2 3.01Å; S13-N16 PolarHBondContact OG-OD1 2.59Å; N16-L18 VanDerWaalsContact C-N 3.28Å; N16-L18 PolarHBondContact O-N 3.4Å; N16-R19 WeakPolarHBondContact O-CB 3.41Å; N16-R19 PolarHBondContact O-N 3.45Å; N16-R19 VanDerWaalsContact O-N 3.16Å; N16-L20 PolarHBondContact O-N 3.38Å; N16-L20 VanDerWaalsContact O-N 3.14Å
17F77.9Confident75.9Confident2 Ų262 Ų621%0.00928%0.279CS..Hα-helixtrans-65.5-31.1172.1-8616.9000112.7R19 L20 L21 F458 T614 T618 L661 Q665 L668F17-R19 VanDerWaalsContact C-N 3.35Å; F17-L20 HydrophobicContact CD1-CD1 3.74Å; F17-L20 HydrophobicContact CE1-CD1 4.06Å; F17-L20 HydrophobicContact CG-CD1 4.5Å; F17-L20 WeakPolarHBondContact O-CB 3.3Å; F17-L20 PolarHBondContact O-N 3.05Å; F17-L21 PolarHBondContact O-N 3.24Å; F17-F458 HydrophobicContact CE2-CE1 4.47Å; F17-T614 HydrophobicContact CD1-CG2 4.35Å; F17-T614 HydrophobicContact CD2-CG2 4.28Å; F17-T614 HydrophobicContact CE1-CG2 4Å; F17-T614 HydrophobicContact CE2-CG2 3.97Å; F17-T614 HydrophobicContact CG-CG2 4.47Å; F17-T614 HydrophobicContact CZ-CG2 3.8Å; F17-T618 HydrophobicContact CB-CG2 3.9Å; F17-T618 WeakPolarHBondContact CD2-OG1 3.46Å; F17-L661 HydrophobicContact CD2-CD1 3.84Å; F17-L661 HydrophobicContact CD2-CD2 4.38Å; F17-L661 HydrophobicContact CD2-CG 4Å; F17-L661 HydrophobicContact CE2-CD1 3.79Å; F17-L661 HydrophobicContact CE2-CG 4.21Å; F17-Q665 HydrophobicContact CD1-CB 4.26Å; F17-Q665 HydrophobicContact CD1-CG 3.76Å; F17-Q665 HydrophobicContact CD2-CB 4.49Å; F17-Q665 HydrophobicContact CE1-CB 3.69Å; F17-Q665 HydrophobicContact CE1-CG 3.4Å; F17-Q665 HydrophobicContact CE2-CB 3.92Å; F17-Q665 HydrophobicContact CE2-CG 4.46Å; F17-Q665 HydrophobicContact CG-CG 4.48Å; F17-Q665 HydrophobicContact CZ-CB 3.49Å; F17-Q665 VanDerWaalsContact CZ-CB 3.49Å; F17-Q665 HydrophobicContact CZ-CG 3.79Å; F17-L668 HydrophobicContact CZ-CD1 4.49Å
18L78.8Confident76.5Confident56 Ų5653.6 Ų53.629%0.29324%0.243SC..Hα-helixtrans-64.8-38.7171.7-67.4174.6000111.6G15 N16 L20 L21 F22 Y622G15-L18 CarbonylContact O-C 3.31Å; G15-L18 WeakPolarHBondContact O-CB 3.34Å; G15-L18 PolarHBondContact O-N 2.81Å; N16-L18 VanDerWaalsContact C-N 3.28Å; N16-L18 PolarHBondContact O-N 3.4Å; L18-L20 VanDerWaalsContact C-N 3.27Å; L18-L20 PolarHBondContact O-N 3.45Å; L18-L21 HydrophobicContact CD2-CD1 3.91Å; L18-L21 VanDerWaalsContact O-CB 3.25Å; L18-L21 WeakPolarHBondContact O-CB 3.33Å; L18-L21 PolarHBondContact O-N 3.44Å; L18-F22 WeakPolarHBondContact O-CD2 3.49Å; L18-Y622 HydrophobicContact CD1-CE1 4.06Å; L18-Y622 HydrophobicContact CD2-CD1 3.98Å; L18-Y622 HydrophobicContact CD2-CD2 3.85Å; L18-Y622 HydrophobicContact CD2-CE1 3.99Å; L18-Y622 HydrophobicContact CD2-CE2 3.86Å; L18-Y622 HydrophobicContact CD2-CG 3.92Å; L18-Y622 HydrophobicContact CG-CE1 4.17Å; L18-Y622 HydrophobicContact CG-CE2 4.12Å
19R82.6Confident77.4Confident167 Ų16753.4 Ų53.463%0.6324%0.239SC*.Hα-helixtrans-61.3-38.4173.4-71.2173.8-174.8169.81.2111.5G15 N16 F17 L21 F22G15-R19 WeakPolarHBondContact O-CG 3.4Å; G15-R19 PolarHBondContact O-N 3.45Å; N16-R19 WeakPolarHBondContact O-CB 3.41Å; N16-R19 PolarHBondContact O-N 3.45Å; N16-R19 VanDerWaalsContact O-N 3.16Å; F17-R19 VanDerWaalsContact C-N 3.35Å; R19-L21 PolarHBondContact O-N 2.88Å; R19-F22 PolarHBondContact O-N 3.32Å
20L81.1Confident78.6Confident1 Ų157.5 Ų57.51%0.00526%0.257CS..Hα-helixtrans-59.1-34.5174-63.8-178.9000111.7Y5 E8 N16 F17 L18 F22 R23 L611 T614 Q615Y5-L20 HydrophobicContact CD2-CD1 3.82Å; Y5-L20 HydrophobicContact CD2-CD2 3.94Å; Y5-L20 HydrophobicContact CE2-CD1 4.04Å; Y5-L20 HydrophobicContact CG-CD2 4.06Å; E8-L20 HydrophobicContact CB-CD2 4.44Å; E8-L20 WeakPolarHBondContact OE2-CD2 3.31Å; N16-L20 PolarHBondContact O-N 3.38Å; N16-L20 VanDerWaalsContact O-N 3.14Å; F17-L20 HydrophobicContact CD1-CD1 3.74Å; F17-L20 HydrophobicContact CE1-CD1 4.06Å; F17-L20 HydrophobicContact CG-CD1 4.5Å; F17-L20 WeakPolarHBondContact O-CB 3.3Å; F17-L20 PolarHBondContact O-N 3.05Å; L18-L20 VanDerWaalsContact C-N 3.27Å; L18-L20 PolarHBondContact O-N 3.45Å; L20-F22 PolarHBondContact O-N 2.88Å; L20-R23 WeakPolarHBondContact O-CB 3.42Å; L20-R23 PolarHBondContact O-N 3.4Å; L20-L611 HydrophobicContact CB-CD1 3.95Å; L20-L611 HydrophobicContact CD1-CD1 4.31Å; L20-L611 HydrophobicContact CD2-CD1 4.01Å; L20-L611 HydrophobicContact CG-CD1 4.32Å; L20-T614 HydrophobicContact CD1-CG2 3.8Å; L20-Q615 PolarHBondContact O-NE2 3.11Å
21L81.6Confident80Confident17 Ų1759 Ų599%0.08926%0.264CS..Hα-helixtrans-62.5-27.2174.4-57.9-175.1000113F17 L18 R19 R23 Y29 Q615 T618 I619F17-L21 PolarHBondContact O-N 3.24Å; L18-L21 HydrophobicContact CD2-CD1 3.91Å; L18-L21 VanDerWaalsContact O-CB 3.25Å; L18-L21 WeakPolarHBondContact O-CB 3.33Å; L18-L21 PolarHBondContact O-N 3.44Å; R19-L21 PolarHBondContact O-N 2.88Å; L21-R23 VanDerWaalsContact C-N 3.31Å; L21-R23 PolarHBondContact O-N 2.97Å; L21-Y29 WeakPolarHBondContact O-CE2 3.32Å; L21-Q615 HydrophobicContact CD2-CB 3.89Å; L21-Q615 HydrophobicContact CD2-CG 3.98Å; L21-T618 HydrophobicContact CD1-CG2 3.98Å; L21-T618 HydrophobicContact CD2-CG2 3.92Å; L21-T618 HydrophobicContact CG-CG2 3.99Å; L21-I619 HydrophobicContact CD1-CG1 4.11Å; L21-I619 HydrophobicContact CD2-CD1 4.1Å; L21-I619 HydrophobicContact CD2-CG1 3.62Å
22F84.3Confident81.1Confident182 Ų18256.3 Ų56.380%0.79825%0.247SC*.THydrogen-bonded Turntrans-87.61.1-178.8-64.8-70.7000113.9L18 R19 L20L18-F22 WeakPolarHBondContact O-CD2 3.49Å; R19-F22 PolarHBondContact O-N 3.32Å; L20-F22 PolarHBondContact O-N 2.88Å
23R84Confident82.2Confident76 Ų7660.1 Ų60.129%0.28727%0.266SS..  trans-78.3132.9174.9-156.2172.6-157.9176.8-1109.8I3 S4 E8 L20 L21 S27 L611I3-R23 VanDerWaalsContact CG2-NH1 3.27Å; S4-R23 PolarHBondContact O-NH1 2.94Å; S4-R23 PolarHBondContact O-NH2 3.34Å; E8-R23 IonicContact OE1-NH1 2.79Å; L20-R23 WeakPolarHBondContact O-CB 3.42Å; L20-R23 PolarHBondContact O-N 3.4Å; L21-R23 VanDerWaalsContact C-N 3.31Å; L21-R23 PolarHBondContact O-N 2.97Å; R23-S27 WeakPolarHBondContact O-CB 3.46Å; R23-S27 PolarHBondContact O-OG 3.4Å; R23-L611 HydrophobicContact CB-CD2 4.08Å; R23-L611 HydrophobicContact CG-CD2 4.2Å
24W85.4Confident83Confident141 Ų14167.5 Ų67.553%0.53429%0.287SS..  trans-90.3-47.5-177-178.8-111.1000114.4S27 K30 L33W24-S27 WeakPolarHBondContact O-CB 3.34Å; W24-S27 PolarHBondContact O-N 3.05Å; W24-S27 PolarHBondContact O-OG 2.94Å; W24-K30 HydrophobicContact CD2-CB 4.28Å; W24-K30 HydrophobicContact CH2-CB 4.33Å; W24-K30 HydrophobicContact CZ2-CB 4.04Å; W24-K30 HydrophobicContact CZ2-CG 4.25Å; W24-K30 WeakPolarHBondContact O-CB 3.49Å; W24-L33 HydrophobicContact CH2-CD2 4.15Å; W24-L33 HydrophobicContact CZ2-CD2 4.48Å
25R82.4Confident84Confident175 Ų17566.5 Ų66.566%0.6628%0.281SS*.THydrogen-bonded Turntrans-70.1139.9176.8-67.2-171.9177.7-179.8-1109.7I3 S27I3-R25 HydrophobicContact CD1-CB 3.35Å; I3-R25 WeakPolarHBondContact CD1-O 3.48Å; R25-S27 PolarHBondContact O-N 2.92Å
26G76.4Confident84.9Confident0 Ų067.5 Ų67.50%029%0.285CS..THydrogen-bonded Turntrans60.222.7-175.700000113.7D302G26-D302 WeakPolarHBondContact CA-OD2 3.33Å; G26-D302 PolarHBondContact N-OD2 3.17Å
27S87Confident85.7Confident0 Ų072.6 Ų72.60%031%0.311CS..  trans-98.3153.1-175.178.80000112.7R23 W24 R25 Y29 K30 I31R23-S27 WeakPolarHBondContact O-CB 3.46Å; R23-S27 PolarHBondContact O-OG 3.4Å; W24-S27 WeakPolarHBondContact O-CB 3.34Å; W24-S27 PolarHBondContact O-N 3.05Å; W24-S27 PolarHBondContact O-OG 2.94Å; R25-S27 PolarHBondContact O-N 2.92Å; S27-Y29 PolarHBondContact O-N 2.88Å; S27-Y29 PolarHBondContact OG-N 2.97Å; S27-K30 PolarHBondContact O-N 3.26Å; S27-K30 PolarHBondContact OG-N 3.33Å; S27-K30 VanDerWaalsContact OG-N 3.14Å; S27-I31 WeakPolarHBondContact O-CG1 3.47Å; S27-I31 PolarHBondContact O-N 2.88Å
28I85.2Confident86.5Confident1 Ų177.6 Ų77.61%0.00534%0.337CS..Hα-helixtrans-54.6-37.7170.2-163-170.4000111.6I31 L32 V612 Q615 V616 I619I28-I31 PolarHBondContact O-N 3.19Å; I28-L32 HydrophobicContact CD1-CD1 3.88Å; I28-L32 HydrophobicContact CG1-CD1 3.57Å; I28-L32 HydrophobicContact CG1-CG 4.14Å; I28-L32 VanDerWaalsContact O-CB 3.27Å; I28-L32 WeakPolarHBondContact O-CB 3.38Å; I28-L32 WeakPolarHBondContact O-CG 3.21Å; I28-L32 PolarHBondContact O-N 3.36Å; I28-V612 HydrophobicContact CB-CG2 3.99Å; I28-V612 HydrophobicContact CG1-CG2 4.24Å; I28-Q615 HydrophobicContact CB-CB 4.37Å; I28-Q615 HydrophobicContact CG2-CB 4.04Å; I28-V616 HydrophobicContact CD1-CB 4.4Å; I28-V616 HydrophobicContact CD1-CG2 3.41Å; I28-V616 VanDerWaalsContact CD1-CG2 3.41Å; I28-V616 HydrophobicContact CG1-CG2 4Å; I28-I619 HydrophobicContact CD1-CD1 4Å; I28-I619 HydrophobicContact CG2-CD1 3.71Å
29Y87.3Confident87.3Confident79 Ų7975.5 Ų75.531%0.3133%0.325SS..Hα-helixtrans-68.2-42.8-179-52.4-75.7000111.8L21 S27 I31 L33 I619L21-Y29 WeakPolarHBondContact O-CE2 3.32Å; S27-Y29 PolarHBondContact O-N 2.88Å; S27-Y29 PolarHBondContact OG-N 2.97Å; Y29-I31 VanDerWaalsContact C-N 3.3Å; Y29-I31 PolarHBondContact O-N 3.47Å; Y29-L33 WeakPolarHBondContact O-CB 3.36Å; Y29-L33 PolarHBondContact O-N 3.31Å; Y29-I619 HydrophobicContact CE1-CD1 4.34Å
30K87.5Confident87.8Confident88 Ų8869.1 Ų69.138%0.38331%0.305SS..Hα-helixtrans-61.1-42.9176.7179.1-174.5168.4-168.70110.7W24 S27 D302W24-K30 HydrophobicContact CD2-CB 4.28Å; W24-K30 HydrophobicContact CH2-CB 4.33Å; W24-K30 HydrophobicContact CZ2-CB 4.04Å; W24-K30 HydrophobicContact CZ2-CG 4.25Å; W24-K30 WeakPolarHBondContact O-CB 3.49Å; S27-K30 PolarHBondContact O-N 3.26Å; S27-K30 PolarHBondContact OG-N 3.33Å; S27-K30 VanDerWaalsContact OG-N 3.14Å; K30-D302 IonicContact NZ-OD1 2.91Å; K30-D302 PolarHBondContact NZ-OD1 3.44Å; K30-D302 IonicContact NZ-OD2 3.27Å; K30-D302 PolarHBondContact NZ-OD2 3.24Å
31I86Confident88.5Confident40 Ų4072.6 Ų72.621%0.20533%0.326CS..Hα-helixtrans-77.1-32.7-175.7-61.3160.8000111.9S27 I28 Y29 K289 V293 V612S27-I31 WeakPolarHBondContact O-CG1 3.47Å; S27-I31 PolarHBondContact O-N 2.88Å; I28-I31 PolarHBondContact O-N 3.19Å; Y29-I31 VanDerWaalsContact C-N 3.3Å; Y29-I31 PolarHBondContact O-N 3.47Å; I31-K289 HydrophobicContact CG2-CB 3.79Å; I31-K289 HydrophobicContact CG2-CD 3.81Å; I31-K289 HydrophobicContact CG2-CG 3.77Å; I31-V293 HydrophobicContact CD1-CG2 3.93Å; I31-V612 HydrophobicContact CD1-CB 4.49Å; I31-V612 HydrophobicContact CD1-CG2 4.27Å
32L91Very high89.1Confident1 Ų174.2 Ų74.21%0.00534%0.337CS..Hα-helixtrans-92-9.3-179.5-69.2179.9000114.7I28 R34 E35 T36 L282 M285 K289I28-L32 HydrophobicContact CD1-CD1 3.88Å; I28-L32 HydrophobicContact CG1-CD1 3.57Å; I28-L32 HydrophobicContact CG1-CG 4.14Å; I28-L32 VanDerWaalsContact O-CB 3.27Å; I28-L32 WeakPolarHBondContact O-CB 3.38Å; I28-L32 WeakPolarHBondContact O-CG 3.21Å; I28-L32 PolarHBondContact O-N 3.36Å; L32-R34 PolarHBondContact O-N 3.43Å; L32-R34 VanDerWaalsContact O-N 3.11Å; L32-E35 PolarHBondContact O-N 3.15Å; L32-E35 VanDerWaalsContact O-N 3.16Å; L32-T36 WeakPolarHBondContact O-CB 3.44Å; L32-T36 PolarHBondContact O-N 2.87Å; L32-T36 PolarHBondContact O-OG1 2.97Å; L32-T36 VanDerWaalsContact O-OG1 3.14Å; L32-L282 HydrophobicContact CD1-CD2 3.75Å; L32-M285 HydrophobicContact CD2-CB 3.84Å; L32-K289 HydrophobicContact CD2-CB 4.34Å; L32-K289 HydrophobicContact CD2-CG 3.53Å; L32-K289 HydrophobicContact CG-CG 4.46Å
33L91.4Very high89.6Confident103 Ų10365.6 Ų65.654%0.53930%0.299SS..Hα-helixtrans-50.9-44.5-170-178.665.1000112.9W24 Y29 L37W24-L33 HydrophobicContact CH2-CD2 4.15Å; W24-L33 HydrophobicContact CZ2-CD2 4.48Å; Y29-L33 WeakPolarHBondContact O-CB 3.36Å; Y29-L33 PolarHBondContact O-N 3.31Å; L33-L37 WeakPolarHBondContact O-CB 3.41Å; L33-L37 PolarHBondContact O-N 3.28Å; L33-L37 VanDerWaalsContact O-N 3.08Å
34R91.1Very high90Very high199 Ų19965.4 Ų65.475%0.75130%0.298SS*.Hα-helixtrans-70.5-48.4-177.4-66.8179.5178.4175.2-0.3111.1L32 L37 I38L32-R34 PolarHBondContact O-N 3.43Å; L32-R34 VanDerWaalsContact O-N 3.11Å; R34-L37 PolarHBondContact O-N 2.55Å; R34-I38 VanDerWaalsContact O-CG1 3.29Å; R34-I38 WeakPolarHBondContact O-CG1 3.28Å; R34-I38 PolarHBondContact O-N 3.42Å
35E92.6Very high90.5Very high50 Ų5063.6 Ų63.623%0.23430%0.299CS..Hα-helixtrans-63.2-43-179.6-70.283.5166.600111.3L32 I38 F39 F281 M285 K289L32-E35 PolarHBondContact O-N 3.15Å; L32-E35 VanDerWaalsContact O-N 3.16Å; E35-I38 PolarHBondContact O-N 3.44Å; E35-F39 WeakPolarHBondContact O-CB 3.4Å; E35-F39 PolarHBondContact O-N 2.91Å; E35-F281 HydrophobicContact CB-CE1 4.19Å; E35-F281 HydrophobicContact CB-CZ 4.01Å; E35-M285 HydrophobicContact CG-CE 4.39Å; E35-K289 WeakPolarHBondContact OE1-CE 3.5Å; E35-K289 IonicContact OE1-NZ 3.34Å; E35-K289 PolarHBondContact OE1-NZ 3.36Å
36T92.8Very high91Very high32 Ų3256.7 Ų56.720%0.19628%0.275CS..Hα-helixtrans-64.5-41.6175.4-60.40000111.5L32 T40L32-T36 WeakPolarHBondContact O-CB 3.44Å; L32-T36 PolarHBondContact O-N 2.87Å; L32-T36 PolarHBondContact O-OG1 2.97Å; L32-T36 VanDerWaalsContact O-OG1 3.14Å; T36-T40 VanDerWaalsContact O-CB 3.3Å; T36-T40 WeakPolarHBondContact O-CB 3.37Å; T36-T40 PolarHBondContact O-N 3.1Å; T36-T40 PolarHBondContact O-OG1 3.32Å
37L94Very high91.7Very high114 Ų11457.6 Ų57.660%0.59728%0.279SS*.Hα-helixtrans-62.1-49.9175.5-176.570.4000111.6L33 R34 F39 T40 V41L33-L37 WeakPolarHBondContact O-CB 3.41Å; L33-L37 PolarHBondContact O-N 3.28Å; L33-L37 VanDerWaalsContact O-N 3.08Å; R34-L37 PolarHBondContact O-N 2.55Å; L37-F39 PolarHBondContact O-N 2.7Å; L37-T40 PolarHBondContact O-N 3.28Å; L37-V41 VanDerWaalsContact O-CG2 3.31Å; L37-V41 WeakPolarHBondContact O-CG2 3.41Å; L37-V41 PolarHBondContact O-N 3.29Å
38I94.8Very high91.9Very high108 Ų10861.4 Ų61.455%0.55430%0.299SS*.Hα-helixtrans-59.1-49.3178-68.1165.4000110.1R34 E35 T40 V41 V42R34-I38 VanDerWaalsContact O-CG1 3.29Å; R34-I38 WeakPolarHBondContact O-CG1 3.28Å; R34-I38 PolarHBondContact O-N 3.42Å; E35-I38 PolarHBondContact O-N 3.44Å; I38-T40 VanDerWaalsContact C-N 3.29Å; I38-T40 PolarHBondContact O-N 3.39Å; I38-V41 PolarHBondContact O-N 3.26Å; I38-V42 HydrophobicContact CG2-CG2 4.23Å; I38-V42 WeakPolarHBondContact O-CB 3.46Å; I38-V42 VanDerWaalsContact O-CG2 3.27Å; I38-V42 WeakPolarHBondContact O-CG2 3.34Å; I38-V42 PolarHBondContact O-N 3.36Å
39F95Very high92.3Very high12 Ų1264.7 Ų64.75%0.05332%0.316CS..Hα-helixtrans-58.1-42.6179.4-178.5-97.4000112E35 L37 Y43 F251 L255 L277 L278 F281E35-F39 WeakPolarHBondContact O-CB 3.4Å; E35-F39 PolarHBondContact O-N 2.91Å; L37-F39 PolarHBondContact O-N 2.7Å; F39-Y43 WeakPolarHBondContact O-CB 3.36Å; F39-Y43 PolarHBondContact O-N 3.1Å; F39-F251 HydrophobicContact CD2-CB 4.45Å; F39-F251 HydrophobicContact CE2-CB 3.89Å; F39-F251 AromaticContact CE2-CD1 3.97Å; F39-F251 HydrophobicContact CE2-CD1 3.97Å; F39-F251 HydrophobicContact CE2-CG 4.26Å; F39-F251 HydrophobicContact CZ-CD1 4.09Å; F39-L255 HydrophobicContact CD2-CD1 4.32Å; F39-L255 HydrophobicContact CD2-CD2 3.85Å; F39-L255 HydrophobicContact CD2-CG 4.12Å; F39-L255 HydrophobicContact CE1-CD2 4.47Å; F39-L255 HydrophobicContact CE2-CD1 4.27Å; F39-L255 HydrophobicContact CE2-CD2 3.55Å; F39-L255 HydrophobicContact CE2-CG 3.64Å; F39-L255 HydrophobicContact CG-CD2 4.44Å; F39-L255 HydrophobicContact CZ-CD2 3.9Å; F39-L255 HydrophobicContact CZ-CG 4.29Å; F39-L277 HydrophobicContact CE1-CD2 3.93Å; F39-L277 HydrophobicContact CE1-CG 3.81Å; F39-L277 HydrophobicContact CZ-CD1 3.94Å; F39-L277 HydrophobicContact CZ-CD2 3.67Å; F39-L277 HydrophobicContact CZ-CG 3.65Å; F39-L278 HydrophobicContact CD1-CD2 3.99Å; F39-L278 HydrophobicContact CE1-CD2 4.2Å; F39-F281 HydrophobicContact CB-CD2 4.2Å; F39-F281 HydrophobicContact CB-CE1 4.28Å; F39-F281 HydrophobicContact CB-CE2 3.67Å; F39-F281 HydrophobicContact CB-CZ 3.69Å; F39-F281 HydrophobicContact CD1-CB 4.44Å; F39-F281 AromaticContact CD1-CD2 3.79Å; F39-F281 HydrophobicContact CD1-CD2 3.79Å; F39-F281 HydrophobicContact CD1-CE2 4.15Å; F39-F281 HydrophobicContact CD1-CG 4.03Å; F39-F281 AromaticContact CD2-CD2 3.53Å; F39-F281 HydrophobicContact CD2-CD2 3.53Å; F39-F281 AromaticContact CD2-CE2 3.37Å; F39-F281 HydrophobicContact CD2-CE2 3.37Å; F39-F281 HydrophobicContact CD2-CZ 4.27Å; F39-F281 HydrophobicContact CE1-CB 4.26Å; F39-F281 AromaticContact CE1-CD2 3.99Å; F39-F281 HydrophobicContact CE1-CD2 3.99Å; F39-F281 HydrophobicContact CE1-CG 4.25Å; F39-F281 AromaticContact CE2-CD2 3.73Å; F39-F281 HydrophobicContact CE2-CD2 3.73Å; F39-F281 HydrophobicContact CE2-CE2 4Å; F39-F281 AromaticContact CG-CD2 3.55Å; F39-F281 HydrophobicContact CG-CD2 3.55Å; F39-F281 AromaticContact CG-CE2 3.44Å; F39-F281 HydrophobicContact CG-CE2 3.44Å; F39-F281 VanDerWaalsContact CG-CE2 3.44Å; F39-F281 HydrophobicContact CG-CG 4.16Å; F39-F281 AromaticContact CG-CZ 3.98Å; F39-F281 HydrophobicContact CG-CZ 3.98Å; F39-F281 AromaticContact CZ-CD2 3.95Å; F39-F281 HydrophobicContact CZ-CD2 3.95Å
40T92.9Very high92.6Very high32 Ų3260.9 Ų60.920%0.19630%0.301CS..Hα-helixtrans-67.8-44.2179.4-55.90000111.3T36 L37 I38 Y43 Y44T36-T40 VanDerWaalsContact O-CB 3.3Å; T36-T40 WeakPolarHBondContact O-CB 3.37Å; T36-T40 PolarHBondContact O-N 3.1Å; T36-T40 PolarHBondContact O-OG1 3.32Å; L37-T40 PolarHBondContact O-N 3.28Å; I38-T40 VanDerWaalsContact C-N 3.29Å; I38-T40 PolarHBondContact O-N 3.39Å; T40-Y43 WeakPolarHBondContact O-CB 3.32Å; T40-Y43 PolarHBondContact O-N 3.16Å; T40-Y44 HydrophobicContact CG2-CD2 3.88Å; T40-Y44 HydrophobicContact CG2-CE2 3.6Å; T40-Y44 WeakPolarHBondContact O-CD2 3.17Å; T40-Y44 PolarHBondContact O-N 2.94Å; T40-Y44 VanDerWaalsContact O-N 3.12Å
41V95Very high92.7Very high75 Ų7560 Ų6046%0.45530%0.295SS..Hα-helixtrans-61.6-48.1176.4168.90000110.7L37 I38 Y43 Y44 L45L37-V41 VanDerWaalsContact O-CG2 3.31Å; L37-V41 WeakPolarHBondContact O-CG2 3.41Å; L37-V41 PolarHBondContact O-N 3.29Å; I38-V41 PolarHBondContact O-N 3.26Å; V41-Y43 VanDerWaalsContact C-N 3.32Å; V41-Y43 PolarHBondContact O-N 3.48Å; V41-Y44 PolarHBondContact O-N 2.66Å; V41-L45 HydrophobicContact CG1-CD1 3.95Å; V41-L45 HydrophobicContact CG1-CG 4.31Å; V41-L45 WeakPolarHBondContact O-CG 3.44Å; V41-L45 PolarHBondContact O-N 3.49Å
42V95.7Very high93Very high51 Ų5167.1 Ų67.131%0.30932%0.321SS..Hα-helixtrans-63.4-39.5179.1177.10000111.2I38 Y44 L45 I46 L255I38-V42 HydrophobicContact CG2-CG2 4.23Å; I38-V42 WeakPolarHBondContact O-CB 3.46Å; I38-V42 VanDerWaalsContact O-CG2 3.27Å; I38-V42 WeakPolarHBondContact O-CG2 3.34Å; I38-V42 PolarHBondContact O-N 3.36Å; V42-Y44 VanDerWaalsContact C-N 3.35Å; V42-Y44 PolarHBondContact O-N 3.28Å; V42-L45 PolarHBondContact O-N 3.44Å; V42-I46 HydrophobicContact CG1-CD1 3.91Å; V42-I46 HydrophobicContact CG1-CG1 4.45Å; V42-I46 WeakPolarHBondContact O-CG1 3.11Å; V42-I46 PolarHBondContact O-N 3.05Å; V42-L255 HydrophobicContact CB-CD1 4.34Å; V42-L255 HydrophobicContact CG1-CD1 3.66Å; V42-L255 HydrophobicContact CG1-CD2 4.37Å
43Y93.9Very high93.2Very high1 Ų172.6 Ų72.60%0.00435%0.35CS..Hα-helixtrans-55.9-49.3174.8-179.8-89.5000111.6F39 T40 V41 I46 N47 L255 R258 Q259 P274 L277F39-Y43 WeakPolarHBondContact O-CB 3.36Å; F39-Y43 PolarHBondContact O-N 3.1Å; T40-Y43 WeakPolarHBondContact O-CB 3.32Å; T40-Y43 PolarHBondContact O-N 3.16Å; V41-Y43 VanDerWaalsContact C-N 3.32Å; V41-Y43 PolarHBondContact O-N 3.48Å; Y43-I46 PolarHBondContact O-N 3.39Å; Y43-N47 WeakPolarHBondContact O-CB 3.45Å; Y43-N47 PolarHBondContact O-N 3.45Å; Y43-L255 HydrophobicContact CD2-CD2 4.21Å; Y43-R258 PolarHBondContact OH-O 3.23Å; Y43-Q259 PolarHBondContact O-NE2 3.14Å; Y43-P274 HydrophobicContact CD1-CB 4.33Å; Y43-P274 HydrophobicContact CD1-CG 3.73Å; Y43-P274 HydrophobicContact CD2-CB 4.49Å; Y43-P274 HydrophobicContact CD2-CG 4.46Å; Y43-P274 HydrophobicContact CE1-CB 3.78Å; Y43-P274 HydrophobicContact CE1-CG 3.57Å; Y43-P274 HydrophobicContact CE2-CB 3.96Å; Y43-P274 HydrophobicContact CE2-CG 4.34Å; Y43-P274 HydrophobicContact CG-CG 4.18Å; Y43-L277 HydrophobicContact CD2-CD2 3.8Å; Y43-L277 HydrophobicContact CE2-CD2 3.81Å
44Y93Very high93.4Very high71 Ų7169.5 Ų69.528%0.27833%0.333SS..Hα-helixtrans-72.2-29.6179.6-73-63.2000113.4T40 V41 V42 N47 I48 Y272T40-Y44 HydrophobicContact CG2-CD2 3.88Å; T40-Y44 HydrophobicContact CG2-CE2 3.6Å; T40-Y44 WeakPolarHBondContact O-CD2 3.17Å; T40-Y44 PolarHBondContact O-N 2.94Å; T40-Y44 VanDerWaalsContact O-N 3.12Å; V41-Y44 PolarHBondContact O-N 2.66Å; V42-Y44 VanDerWaalsContact C-N 3.35Å; V42-Y44 PolarHBondContact O-N 3.28Å; Y44-N47 WeakPolarHBondContact O-CB 3.06Å; Y44-N47 PolarHBondContact O-N 3.15Å; Y44-I48 VanDerWaalsContact O-CG1 3.28Å; Y44-I48 WeakPolarHBondContact O-CG1 3.42Å; Y44-I48 PolarHBondContact O-N 3.03Å; Y44-Y272 PolarHBondContact OH-O 3.29Å
45L95.2Very high93.5Very high104 Ų10464.1 Ų64.155%0.54532%0.319SS..Hα-helixtrans-64.5-42.8172.5-72.5174.7000111.7V41 V42 N47 I48 L49V41-L45 HydrophobicContact CG1-CD1 3.95Å; V41-L45 HydrophobicContact CG1-CG 4.31Å; V41-L45 WeakPolarHBondContact O-CG 3.44Å; V41-L45 PolarHBondContact O-N 3.49Å; V42-L45 PolarHBondContact O-N 3.44Å; L45-N47 VanDerWaalsContact C-N 3.31Å; L45-I48 PolarHBondContact O-N 3.21Å; L45-L49 WeakPolarHBondContact O-CB 3.35Å; L45-L49 PolarHBondContact O-N 3.06Å
46I93.9Very high93.5Very high30 Ų3067.5 Ų67.515%0.15434%0.335CS..Hα-helixtrans-66.4-38.3174.7-65166.4000110.4V42 Y43 L49 Y50 F62 L255 Q259V42-I46 HydrophobicContact CG1-CD1 3.91Å; V42-I46 HydrophobicContact CG1-CG1 4.45Å; V42-I46 WeakPolarHBondContact O-CG1 3.11Å; V42-I46 PolarHBondContact O-N 3.05Å; Y43-I46 PolarHBondContact O-N 3.39Å; I46-L49 WeakPolarHBondContact O-CB 3.42Å; I46-L49 PolarHBondContact O-N 2.68Å; I46-Y50 PolarHBondContact O-N 3.44Å; I46-F62 HydrophobicContact CG2-CE2 4.04Å; I46-F62 HydrophobicContact CG2-CZ 3.89Å; I46-L255 HydrophobicContact CD1-CB 3.8Å; I46-Q259 HydrophobicContact CG2-CG 3.76Å
47N91.2Very high93.5Very high18 Ų1871.8 Ų71.810%0.09635%0.353CS..Hα-helixtrans-59.2-49.3174.6-169.6-96.3000111.4Y43 Y44 L45 L49 Y50 W51 Q259 S260Y43-N47 WeakPolarHBondContact O-CB 3.45Å; Y43-N47 PolarHBondContact O-N 3.45Å; Y44-N47 WeakPolarHBondContact O-CB 3.06Å; Y44-N47 PolarHBondContact O-N 3.15Å; L45-N47 VanDerWaalsContact C-N 3.31Å; N47-L49 VanDerWaalsContact C-N 3.33Å; N47-L49 PolarHBondContact O-N 2.9Å; N47-Y50 PolarHBondContact O-N 3.28Å; N47-W51 VanDerWaalsContact O-CD1 3.24Å; N47-W51 PolarHBondContact O-N 3.43Å; N47-Q259 VanDerWaalsContact CA-OE1 3.3Å; N47-Q259 VanDerWaalsContact CB-OE1 3.29Å; N47-Q259 PolarHBondContact ND2-OE1 3.49Å; N47-Q259 VanDerWaalsContact ND2-OE1 3.13Å; N47-S260 PolarHBondContact ND2-OG 3.02Å
48I91.5Very high93.6Very high81 Ų8169.5 Ų69.542%0.41534%0.341SS..Hα-helixtrans-61.3-42.5177-70165.4000111.1Y44 L45 Y50 W51 Y52Y44-I48 VanDerWaalsContact O-CG1 3.28Å; Y44-I48 WeakPolarHBondContact O-CG1 3.42Å; Y44-I48 PolarHBondContact O-N 3.03Å; L45-I48 PolarHBondContact O-N 3.21Å; I48-Y50 PolarHBondContact O-N 2.99Å; I48-W51 PolarHBondContact O-N 3.21Å; I48-Y52 HydrophobicContact CB-CD2 4.43Å; I48-Y52 HydrophobicContact CG2-CD2 4.12Å; I48-Y52 WeakPolarHBondContact O-CB 3.49Å; I48-Y52 PolarHBondContact O-N 3.21Å
49L93.6Very high93.5Very high69 Ų6965 Ų6536%0.36132%0.318SS..Iπ-helixtrans-55.8-49.9175.9176.971.6000111.1L45 I46 N47 I53 L54L45-L49 WeakPolarHBondContact O-CB 3.35Å; L45-L49 PolarHBondContact O-N 3.06Å; I46-L49 WeakPolarHBondContact O-CB 3.42Å; I46-L49 PolarHBondContact O-N 2.68Å; N47-L49 VanDerWaalsContact C-N 3.33Å; N47-L49 PolarHBondContact O-N 2.9Å; L49-I53 HydrophobicContact CD1-CB 3.99Å; L49-I53 HydrophobicContact CD1-CD1 4.07Å; L49-I53 HydrophobicContact CD1-CG2 3.96Å; L49-I53 WeakPolarHBondContact O-CB 2.94Å; L49-I53 PolarHBondContact O-N 3.42Å; L49-I53 VanDerWaalsContact O-N 3.15Å; L49-L54 HydrophobicContact CD1-CD2 4.41Å; L49-L54 HydrophobicContact CG-CD2 4.48Å; L49-L54 HydrophobicContact CG-CG 4.37Å; L49-L54 WeakPolarHBondContact O-CG 3.44Å; L49-L54 PolarHBondContact O-N 2.98Å
50Y92.1Very high93.4Very high0 Ų067.8 Ų67.80%034%0.336CS..Iπ-helixtrans-64.2-47.1-179.6174.9-90.9000112.7I46 N47 I48 L54 K59 F62 E63 T261 Y262I46-Y50 PolarHBondContact O-N 3.44Å; N47-Y50 PolarHBondContact O-N 3.28Å; I48-Y50 PolarHBondContact O-N 2.99Å; Y50-L54 HydrophobicContact CD2-CD1 4.34Å; Y50-K59 HydrophobicContact CD2-CG 4.24Å; Y50-K59 HydrophobicContact CE2-CB 3.93Å; Y50-K59 HydrophobicContact CE2-CG 3.84Å; Y50-K59 WeakPolarHBondContact O-CE 3.17Å; Y50-F62 HydrophobicContact CD2-CB 4.33Å; Y50-F62 AromaticContact CD2-CD1 3.43Å; Y50-F62 HydrophobicContact CD2-CD1 3.43Å; Y50-F62 VanDerWaalsContact CD2-CD1 3.43Å; Y50-F62 AromaticContact CD2-CE1 3.87Å; Y50-F62 HydrophobicContact CD2-CE1 3.87Å; Y50-F62 AromaticContact CD2-CG 3.9Å; Y50-F62 HydrophobicContact CD2-CG 3.9Å; Y50-F62 AromaticContact CE2-CD1 3.85Å; Y50-F62 HydrophobicContact CE2-CD1 3.85Å; Y50-F62 HydrophobicContact CE2-CG 4.47Å; Y50-F62 HydrophobicContact CG-CD1 4.38Å; Y50-F62 HydrophobicContact CG-CE1 4.42Å; Y50-E63 HydrophobicContact CE2-CG 4.19Å; Y50-E63 PolarHBondContact OH-OE1 2.88Å; Y50-T261 HydrophobicContact CD2-CG2 4.19Å; Y50-T261 HydrophobicContact CE1-CG2 4.1Å; Y50-T261 HydrophobicContact CE2-CG2 3.68Å; Y50-T261 VanDerWaalsContact OH-CA 3.3Å; Y50-T261 WeakPolarHBondContact OH-CA 3.31Å; Y50-T261 VanDerWaalsContact OH-CB 3.31Å; Y50-T261 WeakPolarHBondContact OH-CB 3.38Å; Y50-Y262 HydrophobicContact CE1-CD2 4.18Å; Y50-Y262 WeakPolarHBondContact OH-CD2 3.05Å; Y50-Y262 PolarHBondContact OH-N 3.38Å
51W90.4Very high93.5Very high68 Ų6871.2 Ų71.226%0.25835%0.348SS..Iπ-helixtrans-79-33.8-172.3-76.4105000114.2N47 I48 S260 Y262N47-W51 VanDerWaalsContact O-CD1 3.24Å; N47-W51 PolarHBondContact O-N 3.43Å; I48-W51 PolarHBondContact O-N 3.21Å; W51-S260 PolarHBondContact NE1-O 3.32Å; W51-S260 PolarHBondContact NE1-OG 3.37Å; W51-S260 VanDerWaalsContact NE1-OG 3.1Å; W51-Y262 AromaticContact CE3-CE2 3.82Å; W51-Y262 HydrophobicContact CE3-CE2 3.82Å; W51-Y262 HydrophobicContact CH2-CD2 4.33Å; W51-Y262 HydrophobicContact CH2-CE2 4.28Å; W51-Y262 HydrophobicContact CH2-CG 4.45Å; W51-Y262 HydrophobicContact CZ3-CD1 4.29Å; W51-Y262 AromaticContact CZ3-CD2 3.95Å; W51-Y262 HydrophobicContact CZ3-CD2 3.95Å; W51-Y262 AromaticContact CZ3-CE1 3.88Å; W51-Y262 HydrophobicContact CZ3-CE1 3.88Å; W51-Y262 AromaticContact CZ3-CE2 3.46Å; W51-Y262 HydrophobicContact CZ3-CE2 3.46Å; W51-Y262 VanDerWaalsContact CZ3-CE2 3.46Å; W51-Y262 HydrophobicContact CZ3-CG 4.34Å; W51-Y262 AromaticContact CZ3-CZ 3.45Å; W51-Y262 VanDerWaalsContact CZ3-CZ 3.45Å
52Y92.4Very high93.5Very high190 Ų19069 Ų6975%0.74533%0.332SS*.Iπ-helixtrans-118.3-14-169.1-60.8-77.3000115.2I48I48-Y52 HydrophobicContact CB-CD2 4.43Å; I48-Y52 HydrophobicContact CG2-CD2 4.12Å; I48-Y52 WeakPolarHBondContact O-CB 3.49Å; I48-Y52 PolarHBondContact O-N 3.21Å
53I95.2Very high93.3Very high117 Ų11767.5 Ų67.560%0.632%0.322SS*.Iπ-helixtrans-116.1-43.2-172.7-54.6-178.7000111.8L49L49-I53 HydrophobicContact CD1-CB 3.99Å; L49-I53 HydrophobicContact CD1-CD1 4.07Å; L49-I53 HydrophobicContact CD1-CG2 3.96Å; L49-I53 WeakPolarHBondContact O-CB 2.94Å; L49-I53 PolarHBondContact O-N 3.42Å; L49-I53 VanDerWaalsContact O-N 3.15Å
54L94.7Very high93.3Very high38 Ų3873.7 Ų73.720%0.19935%0.35CS..  trans-69.8137.7-179.5-63.4-175.5000111.6L49 Y50 N58 K59 F62L49-L54 HydrophobicContact CD1-CD2 4.41Å; L49-L54 HydrophobicContact CG-CD2 4.48Å; L49-L54 HydrophobicContact CG-CG 4.37Å; L49-L54 WeakPolarHBondContact O-CG 3.44Å; L49-L54 PolarHBondContact O-N 2.98Å; Y50-L54 HydrophobicContact CD2-CD1 4.34Å; L54-N58 HydrophobicContact CB-CB 4.38Å; L54-N58 HydrophobicContact CD2-CB 4.05Å; L54-K59 HydrophobicContact CB-CG 3.86Å; L54-K59 VanDerWaalsContact O-CE 3.24Å; L54-K59 WeakPolarHBondContact O-CE 3.31Å; L54-F62 HydrophobicContact CD1-CB 4.08Å; L54-F62 HydrophobicContact CD1-CD2 4.24Å; L54-F62 HydrophobicContact CD1-CG 4.31Å
55D94.4Very high93.3Very high86 Ų8673.2 Ų73.246%0.4636%0.355SS..  trans-78.2172167.263.3-0.7000111.2E57 N58 K59D55-E57 VanDerWaalsContact C-N 3.31Å; D55-E57 PolarHBondContact O-N 3.42Å; D55-N58 PolarHBondContact O-N 3.19Å; D55-N58 WeakPolarHBondContact OD1-CB 3.33Å; D55-N58 VanDerWaalsContact OD1-CG 3.23Å; D55-N58 PolarHBondContact OD1-N 3.28Å; D55-N58 PolarHBondContact OD1-ND2 3.25Å; D55-K59 WeakPolarHBondContact O-CG 3.44Å; D55-K59 PolarHBondContact O-N 2.79Å
56E91.3Very high93.2Very high120 Ų12068.4 Ų68.456%0.56133%0.33SS*.Hα-helixtrans-60.5-37.9-174.6-65.2-54130.800113K59 V60E56-K59 PolarHBondContact O-N 2.91Å; E56-K59 IonicContact OE1-NZ 3.02Å; E56-K59 PolarHBondContact OE1-NZ 3.01Å; E56-V60 WeakPolarHBondContact O-CG2 3.32Å; E56-V60 PolarHBondContact O-N 3.44Å
57E94Very high92.9Very high122 Ų12271.6 Ų71.657%0.5735%0.351SS*.Hα-helixtrans-64.6-44.7177.5-166.8-169.2146.600111.7D55 V60 K61D55-E57 VanDerWaalsContact C-N 3.31Å; D55-E57 PolarHBondContact O-N 3.42Å; E57-V60 PolarHBondContact O-N 3.12Å; E57-K61 PolarHBondContact O-N 3.37Å; E57-K61 WeakPolarHBondContact OE1-CE 3.39Å; E57-K61 IonicContact OE1-NZ 3.64Å; E57-K61 PolarHBondContact OE1-NZ 3.47Å
58N95.3Very high93Very high66 Ų6677.1 Ų77.135%0.35337%0.372SS..Hα-helixtrans-76-27.5-179.6-67.4-53.1000113L54 D55 K61 F62L54-N58 HydrophobicContact CB-CB 4.38Å; L54-N58 HydrophobicContact CD2-CB 4.05Å; D55-N58 PolarHBondContact O-N 3.19Å; D55-N58 WeakPolarHBondContact OD1-CB 3.33Å; D55-N58 VanDerWaalsContact OD1-CG 3.23Å; D55-N58 PolarHBondContact OD1-N 3.28Å; D55-N58 PolarHBondContact OD1-ND2 3.25Å; N58-K61 PolarHBondContact O-N 3.37Å; N58-F62 WeakPolarHBondContact O-CB 3.49Å; N58-F62 PolarHBondContact O-N 2.92Å
59K93.8Very high93.1Very high13 Ų1375.9 Ų75.96%0.05736%0.363CS..Hα-helixtrans-60.2-45.4169.7-76.1175.8-175166.40111.6Y50 L54 D55 E56 K61 F62 E63 Y262Y50-K59 HydrophobicContact CD2-CG 4.24Å; Y50-K59 HydrophobicContact CE2-CB 3.93Å; Y50-K59 HydrophobicContact CE2-CG 3.84Å; Y50-K59 WeakPolarHBondContact O-CE 3.17Å; L54-K59 HydrophobicContact CB-CG 3.86Å; L54-K59 VanDerWaalsContact O-CE 3.24Å; L54-K59 WeakPolarHBondContact O-CE 3.31Å; D55-K59 WeakPolarHBondContact O-CG 3.44Å; D55-K59 PolarHBondContact O-N 2.79Å; E56-K59 PolarHBondContact O-N 2.91Å; E56-K59 IonicContact OE1-NZ 3.02Å; E56-K59 PolarHBondContact OE1-NZ 3.01Å; K59-K61 VanDerWaalsContact C-N 3.34Å; K59-K61 PolarHBondContact O-N 3.13Å; K59-F62 WeakPolarHBondContact O-CB 3.35Å; K59-F62 PolarHBondContact O-N 3.44Å; K59-E63 WeakPolarHBondContact O-CG 3.5Å; K59-E63 PolarHBondContact O-N 2.84Å; K59-Y262 HydrophobicContact CD-CD2 4.12Å; K59-Y262 HydrophobicContact CD-CE2 4.14Å
60V92.5Very high92.7Very high71 Ų7174 Ų7443%0.4336%0.356SS..Hα-helixtrans-61-43.2176.8172.90000111.2E56 E57 E63 H64E56-V60 WeakPolarHBondContact O-CG2 3.32Å; E56-V60 PolarHBondContact O-N 3.44Å; E57-V60 PolarHBondContact O-N 3.12Å; V60-E63 PolarHBondContact O-N 3.03Å; V60-H64 PolarHBondContact O-N 3.42Å; V60-H64 VanDerWaalsContact O-N 3.15Å; V60-H64 PolarHBondContact O-ND1 2.97Å
61K94.4Very high92.4Very high104 Ų10480 Ų8045%0.45238%0.382SS..Hα-helixtrans-61.8-44.1174.9-68.3173.9-170.8161.60111.7E57 N58 K59 E63 H64 V65E57-K61 PolarHBondContact O-N 3.37Å; E57-K61 WeakPolarHBondContact OE1-CE 3.39Å; E57-K61 IonicContact OE1-NZ 3.64Å; E57-K61 PolarHBondContact OE1-NZ 3.47Å; N58-K61 PolarHBondContact O-N 3.37Å; K59-K61 VanDerWaalsContact C-N 3.34Å; K59-K61 PolarHBondContact O-N 3.13Å; K61-E63 VanDerWaalsContact C-N 3.34Å; K61-E63 PolarHBondContact O-N 2.83Å; K61-H64 PolarHBondContact O-N 3.1Å; K61-V65 WeakPolarHBondContact O-CG2 3.38Å; K61-V65 PolarHBondContact O-N 3.16Å
62F94.6Very high92.3Very high30 Ų3080.3 Ų80.313%0.13239%0.385CS..Hα-helixtrans-59.2-44.4177.2-178.5-84.1000111.7I46 Y50 L54 N58 K59 H64 V65 A66 I256 Q259 T261I46-F62 HydrophobicContact CG2-CE2 4.04Å; I46-F62 HydrophobicContact CG2-CZ 3.89Å; Y50-F62 HydrophobicContact CD2-CB 4.33Å; Y50-F62 AromaticContact CD2-CD1 3.43Å; Y50-F62 HydrophobicContact CD2-CD1 3.43Å; Y50-F62 VanDerWaalsContact CD2-CD1 3.43Å; Y50-F62 AromaticContact CD2-CE1 3.87Å; Y50-F62 HydrophobicContact CD2-CE1 3.87Å; Y50-F62 AromaticContact CD2-CG 3.9Å; Y50-F62 HydrophobicContact CD2-CG 3.9Å; Y50-F62 AromaticContact CE2-CD1 3.85Å; Y50-F62 HydrophobicContact CE2-CD1 3.85Å; Y50-F62 HydrophobicContact CE2-CG 4.47Å; Y50-F62 HydrophobicContact CG-CD1 4.38Å; Y50-F62 HydrophobicContact CG-CE1 4.42Å; L54-F62 HydrophobicContact CD1-CB 4.08Å; L54-F62 HydrophobicContact CD1-CD2 4.24Å; L54-F62 HydrophobicContact CD1-CG 4.31Å; N58-F62 WeakPolarHBondContact O-CB 3.49Å; N58-F62 PolarHBondContact O-N 2.92Å; K59-F62 WeakPolarHBondContact O-CB 3.35Å; K59-F62 PolarHBondContact O-N 3.44Å; F62-H64 PolarHBondContact O-N 3.46Å; F62-V65 PolarHBondContact O-N 3.4Å; F62-A66 HydrophobicContact CE1-CB 4.32Å; F62-A66 WeakPolarHBondContact O-CB 3.44Å; F62-A66 PolarHBondContact O-N 2.75Å; F62-I256 HydrophobicContact CE1-CG2 4.3Å; F62-I256 HydrophobicContact CE2-CG1 4.5Å; F62-I256 HydrophobicContact CE2-CG2 3.92Å; F62-I256 HydrophobicContact CZ-CB 4.42Å; F62-I256 HydrophobicContact CZ-CG2 3.73Å; F62-Q259 HydrophobicContact CE1-CB 3.99Å; F62-Q259 HydrophobicContact CE1-CG 4.24Å; F62-Q259 HydrophobicContact CZ-CB 4.18Å; F62-Q259 HydrophobicContact CZ-CG 3.89Å; F62-T261 HydrophobicContact CD1-CG2 4.17Å; F62-T261 HydrophobicContact CE1-CG2 4.09Å
63E92.3Very high92Very high18 Ų1872.1 Ų72.18%0.08435%0.354CS..Hα-helixtrans-63.2-39.4179.4-75.1175.1-174.400113.2Y50 K59 V60 K61 V65 A66 T67 T261 Y262 S263Y50-E63 HydrophobicContact CE2-CG 4.19Å; Y50-E63 PolarHBondContact OH-OE1 2.88Å; K59-E63 WeakPolarHBondContact O-CG 3.5Å; K59-E63 PolarHBondContact O-N 2.84Å; V60-E63 PolarHBondContact O-N 3.03Å; K61-E63 VanDerWaalsContact C-N 3.34Å; K61-E63 PolarHBondContact O-N 2.83Å; E63-V65 VanDerWaalsContact C-N 3.34Å; E63-A66 PolarHBondContact O-N 2.85Å; E63-T67 WeakPolarHBondContact O-CB 3.26Å; E63-T67 PolarHBondContact O-N 3.01Å; E63-T67 PolarHBondContact O-OG1 2.84Å; E63-T261 HydrophobicContact CG-CG2 3.85Å; E63-Y262 PolarHBondContact OE1-N 3.18Å; E63-S263 PolarHBondContact OE1-N 3.47Å; E63-S263 WeakPolarHBondContact OE2-CB 3.45Å; E63-S263 PolarHBondContact OE2-OG 2.97Å
64H93.6Very high91.3Very high131 Ų13172.4 Ų72.461%0.60636%0.356SS*.Hα-helixtrans-61.1-43.9172.7-69.9144.1000111.7V60 K61 F62 T67 Y68V60-H64 PolarHBondContact O-N 3.42Å; V60-H64 VanDerWaalsContact O-N 3.15Å; V60-H64 PolarHBondContact O-ND1 2.97Å; K61-H64 PolarHBondContact O-N 3.1Å; F62-H64 PolarHBondContact O-N 3.46Å; H64-T67 PolarHBondContact O-N 3.32Å; H64-Y68 WeakPolarHBondContact O-CB 3.39Å; H64-Y68 PolarHBondContact O-N 3.2Å
65V94.1Very high90.9Very high61 Ų6175.7 Ų75.737%0.3737%0.371SS..Hα-helixtrans-65.1-44.7177.2175.40000111.1K61 F62 E63 T67 Y68 F69 I256K61-V65 WeakPolarHBondContact O-CG2 3.38Å; K61-V65 PolarHBondContact O-N 3.16Å; F62-V65 PolarHBondContact O-N 3.4Å; E63-V65 VanDerWaalsContact C-N 3.34Å; V65-T67 VanDerWaalsContact C-N 3.34Å; V65-T67 PolarHBondContact O-N 3.35Å; V65-Y68 PolarHBondContact O-N 3.18Å; V65-F69 HydrophobicContact CG1-CD2 3.79Å; V65-F69 HydrophobicContact CG1-CE2 3.42Å; V65-F69 VanDerWaalsContact CG1-CE2 3.42Å; V65-F69 HydrophobicContact CG1-CZ 3.88Å; V65-F69 PolarHBondContact O-N 2.94Å; V65-I256 HydrophobicContact CG1-CG2 4.24Å
66A91.6Very high90.4Very high4 Ų474.6 Ų74.63%0.03337%0.365CS..Hα-helixtrans-60.4-43.3177.900000111.8F62 E63 F69 S70 I256 A257F62-A66 HydrophobicContact CE1-CB 4.32Å; F62-A66 WeakPolarHBondContact O-CB 3.44Å; F62-A66 PolarHBondContact O-N 2.75Å; E63-A66 PolarHBondContact O-N 2.85Å; A66-F69 PolarHBondContact O-N 2.97Å; A66-S70 WeakPolarHBondContact O-CB 3.23Å; A66-S70 PolarHBondContact O-N 2.83Å; A66-I256 HydrophobicContact CB-CG2 4.03Å; A66-I256 WeakPolarHBondContact CB-O 3.38Å; A66-A257 WeakPolarHBondContact O-CA 3.47Å
67T89Confident90.2Very high97 Ų9772.2 Ų72.260%0.59536%0.36SS*.Hα-helixtrans-64.3-45176.7-57.40000111.3E63 H64 V65 F69 S70 F71E63-T67 WeakPolarHBondContact O-CB 3.26Å; E63-T67 PolarHBondContact O-N 3.01Å; E63-T67 PolarHBondContact O-OG1 2.84Å; H64-T67 PolarHBondContact O-N 3.32Å; V65-T67 VanDerWaalsContact C-N 3.34Å; V65-T67 PolarHBondContact O-N 3.35Å; T67-F69 PolarHBondContact O-N 2.98Å; T67-S70 WeakPolarHBondContact O-CB 3.46Å; T67-S70 PolarHBondContact O-N 3.35Å; T67-F71 PolarHBondContact O-N 3.4Å; T67-F71 VanDerWaalsContact O-N 3.09Å
68Y92.5Very high89.9Confident134 Ų13466.5 Ų66.553%0.52533%0.333SS..Hα-helixtrans-58.4-48.9176.3175.5-100.2000112.1H64 V65 S70 F71 K72H64-Y68 WeakPolarHBondContact O-CB 3.39Å; H64-Y68 PolarHBondContact O-N 3.2Å; V65-Y68 PolarHBondContact O-N 3.18Å; Y68-S70 PolarHBondContact O-N 3.43Å; Y68-F71 PolarHBondContact O-N 3.3Å; Y68-K72 HydrophobicContact CD2-CG 4.44Å; Y68-K72 HydrophobicContact CE1-CG 4.05Å; Y68-K72 HydrophobicContact CE2-CG 3.94Å; Y68-K72 PolarHBondContact O-N 3.37Å
69F93Very high89.4Confident54 Ų5464 Ų6424%0.23732%0.32CS..Hα-helixtrans-65.3-37.2176.7-71.9-22.4000112.8V65 A66 T67 F71 K72 N73 T253 I256 A257V65-F69 HydrophobicContact CG1-CD2 3.79Å; V65-F69 HydrophobicContact CG1-CE2 3.42Å; V65-F69 VanDerWaalsContact CG1-CE2 3.42Å; V65-F69 HydrophobicContact CG1-CZ 3.88Å; V65-F69 PolarHBondContact O-N 2.94Å; A66-F69 PolarHBondContact O-N 2.97Å; T67-F69 PolarHBondContact O-N 2.98Å; F69-F71 VanDerWaalsContact C-N 3.26Å; F69-F71 PolarHBondContact O-N 2.95Å; F69-K72 PolarHBondContact O-N 2.97Å; F69-N73 VanDerWaalsContact O-CB 3.31Å; F69-N73 WeakPolarHBondContact O-CB 3.43Å; F69-N73 PolarHBondContact O-N 2.77Å; F69-N73 PolarHBondContact O-ND2 2.72Å; F69-T253 HydrophobicContact CD1-CG2 4.1Å; F69-T253 HydrophobicContact CD2-CG2 4.38Å; F69-T253 HydrophobicContact CE1-CG2 4.25Å; F69-T253 HydrophobicContact CG-CG2 4.18Å; F69-T253 HydrophobicContact CZ-CG2 4.46Å; F69-I256 HydrophobicContact CD2-CB 4.1Å; F69-I256 HydrophobicContact CD2-CD1 4.38Å; F69-I256 HydrophobicContact CD2-CG2 4.11Å; F69-I256 HydrophobicContact CE2-CB 4.47Å; F69-I256 HydrophobicContact CE2-CD1 3.9Å; F69-I256 HydrophobicContact CE2-CG2 4.47Å; F69-A257 HydrophobicContact CB-CB 3.81Å
70S85.4Confident89.1Confident29 Ų2968.2 Ų68.220%0.20334%0.339CS..Hα-helixtrans-58.9-40.2175.8-172.60000111.5A66 T67 Y68A66-S70 WeakPolarHBondContact O-CB 3.23Å; A66-S70 PolarHBondContact O-N 2.83Å; T67-S70 WeakPolarHBondContact O-CB 3.46Å; T67-S70 PolarHBondContact O-N 3.35Å; Y68-S70 PolarHBondContact O-N 3.43Å
71F86.2Confident88.9Confident126 Ų12666.9 Ų66.955%0.55333%0.329SS*.Hα-helixtrans-70.9-49.6176.6-177.2-99.7000111.7T67 Y68 F69 N73 L74 E75T67-F71 PolarHBondContact O-N 3.4Å; T67-F71 VanDerWaalsContact O-N 3.09Å; Y68-F71 PolarHBondContact O-N 3.3Å; F69-F71 VanDerWaalsContact C-N 3.26Å; F69-F71 PolarHBondContact O-N 2.95Å; F71-N73 VanDerWaalsContact C-N 3.33Å; F71-N73 PolarHBondContact O-N 3.46Å; F71-L74 WeakPolarHBondContact O-CB 3.4Å; F71-L74 PolarHBondContact O-N 3.44Å; F71-L74 VanDerWaalsContact O-N 3.14Å; F71-E75 WeakPolarHBondContact CE1-OE1 3.33Å
72K88Confident88.6Confident75 Ų7561.9 Ų61.933%0.32631%0.307SS..Hα-helixtrans-66.7-29.8-176.7-72.4-60.3-179-167.10114.7Y68 F69 L74 E75Y68-K72 HydrophobicContact CD2-CG 4.44Å; Y68-K72 HydrophobicContact CE1-CG 4.05Å; Y68-K72 HydrophobicContact CE2-CG 3.94Å; Y68-K72 PolarHBondContact O-N 3.37Å; F69-K72 PolarHBondContact O-N 2.97Å; K72-L74 PolarHBondContact O-N 2.66Å; K72-E75 WeakPolarHBondContact CD-OE2 3.48Å; K72-E75 IonicContact NZ-OE1 2.78Å; K72-E75 PolarHBondContact NZ-OE1 2.93Å; K72-E75 IonicContact NZ-OE2 2.85Å; K72-E75 PolarHBondContact NZ-OE2 3.09Å; K72-E75 PolarHBondContact O-N 2.84Å; K72-E75 VanDerWaalsContact O-N 3.16Å
73N87.4Confident88.3Confident18 Ų1860.5 Ų60.510%0.09630%0.301CS..Hα-helixtrans-64.6-24.5175-76.9-15.4000113.3F69 F71 E75 F250 T253 N254F69-N73 VanDerWaalsContact O-CB 3.31Å; F69-N73 WeakPolarHBondContact O-CB 3.43Å; F69-N73 PolarHBondContact O-N 2.77Å; F69-N73 PolarHBondContact O-ND2 2.72Å; F71-N73 VanDerWaalsContact C-N 3.33Å; F71-N73 PolarHBondContact O-N 3.46Å; N73-E75 VanDerWaalsContact C-N 3.32Å; N73-F250 HydrophobicContact CB-CD2 4.21Å; N73-F250 HydrophobicContact CB-CE2 4.03Å; N73-T253 PolarHBondContact ND2-OG1 2.95Å; N73-T253 PolarHBondContact OD1-OG1 3.48Å; N73-N254 VanDerWaalsContact ND2-CG 3.3Å; N73-N254 PolarHBondContact ND2-ND2 3.34Å
74L79.8Confident88.2Confident123 Ų12365.2 Ų65.264%0.64432%0.321SS*.Hα-helixtrans-73.9-24.2176.3-62.1170.9000112.5F71 K72 L448F71-L74 WeakPolarHBondContact O-CB 3.4Å; F71-L74 PolarHBondContact O-N 3.44Å; F71-L74 VanDerWaalsContact O-N 3.14Å; K72-L74 PolarHBondContact O-N 2.66Å; L74-L448 HydrophobicContact CD2-CD2 4.17Å
75E85Confident88.2Confident108 Ų10859.1 Ų59.151%0.50529%0.293SS..Hα-helixtrans-79.1-19179.5-63.9177.2-173.200112.6F71 K72 N73 P77F71-E75 WeakPolarHBondContact CE1-OE1 3.33Å; K72-E75 WeakPolarHBondContact CD-OE2 3.48Å; K72-E75 IonicContact NZ-OE1 2.78Å; K72-E75 PolarHBondContact NZ-OE1 2.93Å; K72-E75 IonicContact NZ-OE2 2.85Å; K72-E75 PolarHBondContact NZ-OE2 3.09Å; K72-E75 PolarHBondContact O-N 2.84Å; K72-E75 VanDerWaalsContact O-N 3.16Å; N73-E75 VanDerWaalsContact C-N 3.32Å; E75-P77 VanDerWaalsContact O-CD 3.3Å; E75-P77 WeakPolarHBondContact O-CD 3.43Å
76L84.7Confident88Confident63 Ų6356.2 Ų56.233%0.3328%0.276SS..  trans-77.6116.6-176.3-174.869.5000110.8L78 F250L76-L78 HydrophobicContact CD2-CB 4.3Å; L76-L78 HydrophobicContact CG-CB 4.34Å; L76-L78 PolarHBondContact O-N 2.93Å; L76-F250 HydrophobicContact CD2-CB 3.92Å; L76-F250 HydrophobicContact CD2-CD2 4.09Å; L76-F250 HydrophobicContact CD2-CG 4.44Å
77P86.5Confident87.9Confident70 Ų7057.3 Ų57.346%0.45528%0.281SS..  trans-80.550.7-178.235.2-37.1000111.8E75 T79 F80 I81E75-P77 VanDerWaalsContact O-CD 3.3Å; E75-P77 WeakPolarHBondContact O-CD 3.43Å; P77-T79 PolarHBondContact O-N 3.33Å; P77-F80 HydrophobicContact CB-CB 4.49Å; P77-F80 HydrophobicContact CB-CD2 4.21Å; P77-F80 PolarHBondContact O-N 3.41Å; P77-I81 HydrophobicContact CG-CD1 4.16Å; P77-I81 PolarHBondContact O-N 2.88Å
78L88.2Confident88.1Confident2 Ų257.6 Ų57.61%0.0128%0.275CS..Hα-helixtrans-54.9-41.7-171.6-17660.2000111.8L76 F80 I81 M82 A246 F250 Y284L76-L78 HydrophobicContact CD2-CB 4.3Å; L76-L78 HydrophobicContact CG-CB 4.34Å; L76-L78 PolarHBondContact O-N 2.93Å; L78-F80 PolarHBondContact O-N 3.28Å; L78-I81 PolarHBondContact O-N 2.91Å; L78-M82 HydrophobicContact CD1-CG 3.95Å; L78-M82 HydrophobicContact CD1-SD 4.49Å; L78-M82 HydrophobicContact CG-CG 4.06Å; L78-M82 VanDerWaalsContact O-CB 3.28Å; L78-M82 WeakPolarHBondContact O-CB 3.5Å; L78-M82 WeakPolarHBondContact O-CG 3.27Å; L78-M82 PolarHBondContact O-N 3.34Å; L78-A246 HydrophobicContact CD1-CB 3.97Å; L78-F250 HydrophobicContact CD2-CB 4Å; L78-F250 HydrophobicContact CD2-CD1 3.8Å; L78-F250 HydrophobicContact CD2-CD2 4.3Å; L78-F250 HydrophobicContact CD2-CE1 4.34Å; L78-F250 HydrophobicContact CD2-CG 3.77Å; L78-Y284 HydrophobicContact CB-CE1 4.23Å; L78-Y284 HydrophobicContact CD2-CD1 3.61Å; L78-Y284 HydrophobicContact CD2-CD2 4.26Å; L78-Y284 HydrophobicContact CD2-CE1 3.92Å; L78-Y284 HydrophobicContact CD2-CG 3.79Å; L78-Y284 HydrophobicContact CG-CD1 3.84Å; L78-Y284 HydrophobicContact CG-CE1 3.94Å
79T85.7Confident88.1Confident14 Ų1451.2 Ų51.29%0.08625%0.25CS..Hα-helixtrans-56.9-45.5177.7-47.40000113.3P77 G83 Y284 W287 P450 F453P77-T79 PolarHBondContact O-N 3.33Å; T79-G83 PolarHBondContact O-N 2.92Å; T79-Y284 PolarHBondContact OG1-OH 3Å; T79-Y284 VanDerWaalsContact OG1-OH 3.1Å; T79-W287 HydrophobicContact CG2-CZ3 4.13Å; T79-P450 HydrophobicContact CG2-CB 3.43Å; T79-P450 VanDerWaalsContact CG2-CB 3.43Å; T79-P450 HydrophobicContact CG2-CG 3.47Å; T79-P450 VanDerWaalsContact CG2-CG 3.47Å; T79-P450 WeakPolarHBondContact OG1-CB 3.28Å; T79-P450 WeakPolarHBondContact OG1-CG 3.22Å; T79-F453 HydrophobicContact CG2-CB 3.49Å; T79-F453 VanDerWaalsContact CG2-CB 3.49Å; T79-F453 HydrophobicContact CG2-CD2 3.69Å; T79-F453 HydrophobicContact CG2-CG 3.72Å
80F86.7Confident88Confident100 Ų10048.9 Ų48.944%0.43924%0.24SC..Hα-helixtrans-66.5-47.1-179.3-76.9-86000110P77 L78 M82 G83 F84 F453P77-F80 HydrophobicContact CB-CB 4.49Å; P77-F80 HydrophobicContact CB-CD2 4.21Å; P77-F80 PolarHBondContact O-N 3.41Å; L78-F80 PolarHBondContact O-N 3.28Å; F80-M82 VanDerWaalsContact C-N 3.33Å; F80-M82 PolarHBondContact O-N 3.49Å; F80-G83 PolarHBondContact O-N 2.68Å; F80-F84 VanDerWaalsContact O-CD2 3.23Å; F80-F84 WeakPolarHBondContact O-CD2 3.47Å; F80-F84 PolarHBondContact O-N 3.28Å; F80-F453 HydrophobicContact CD1-CD1 4.41Å; F80-F453 AromaticContact CD1-CE1 3.97Å; F80-F453 HydrophobicContact CD1-CE1 3.97Å; F80-F453 HydrophobicContact CE1-CD1 4.1Å; F80-F453 AromaticContact CE1-CE1 3.24Å; F80-F453 HydrophobicContact CE1-CE1 3.24Å; F80-F453 AromaticContact CE1-CZ 3.65Å; F80-F453 HydrophobicContact CE1-CZ 3.65Å; F80-F453 HydrophobicContact CE2-CE1 4.07Å; F80-F453 HydrophobicContact CE2-CE2 4.19Å; F80-F453 AromaticContact CE2-CZ 3.65Å; F80-F453 HydrophobicContact CE2-CZ 3.65Å; F80-F453 HydrophobicContact CZ-CD1 4.38Å; F80-F453 AromaticContact CZ-CE1 3.32Å; F80-F453 HydrophobicContact CZ-CE1 3.32Å; F80-F453 HydrophobicContact CZ-CE2 4.12Å; F80-F453 AromaticContact CZ-CZ 3.15Å; F80-F453 HydrophobicContact CZ-CZ 3.15Å
81I88.7Confident88.3Confident43 Ų4349.4 Ų49.422%0.22124%0.244CC..Hα-helixtrans-56.2-49.6177.7-65.1168.9000110.3P77 L78 F85 V243P77-I81 HydrophobicContact CG-CD1 4.16Å; P77-I81 PolarHBondContact O-N 2.88Å; L78-I81 PolarHBondContact O-N 2.91Å; I81-F85 WeakPolarHBondContact O-CB 3.33Å; I81-F85 PolarHBondContact O-N 2.95Å; I81-F85 VanDerWaalsContact O-N 3.09Å; I81-V243 HydrophobicContact CG2-CB 4.29Å; I81-V243 HydrophobicContact CG2-CG1 4.32Å; I81-V243 HydrophobicContact CG2-CG2 3.69Å
82M88.1Confident88.5Confident0 Ų045.4 Ų45.40%023%0.225CC..Hα-helixtrans-63.5-45.7178.6-72.3-58-63.800112.4L78 F80 F85 V86 V243 T247 W287 L288L78-M82 HydrophobicContact CD1-CG 3.95Å; L78-M82 HydrophobicContact CD1-SD 4.49Å; L78-M82 HydrophobicContact CG-CG 4.06Å; L78-M82 VanDerWaalsContact O-CB 3.28Å; L78-M82 WeakPolarHBondContact O-CB 3.5Å; L78-M82 WeakPolarHBondContact O-CG 3.27Å; L78-M82 PolarHBondContact O-N 3.34Å; F80-M82 VanDerWaalsContact C-N 3.33Å; F80-M82 PolarHBondContact O-N 3.49Å; M82-F85 PolarHBondContact O-N 2.86Å; M82-V86 HydrophobicContact CE-CG2 4.46Å; M82-V86 WeakPolarHBondContact O-CB 3.2Å; M82-V86 VanDerWaalsContact O-CG2 3.23Å; M82-V86 WeakPolarHBondContact O-CG2 3.3Å; M82-V86 PolarHBondContact O-N 3.47Å; M82-V243 HydrophobicContact CE-CG1 4.46Å; M82-V243 HydrophobicContact SD-CG1 3.28Å; M82-V243 WeakPolarHBondContact SD-CG1 3.48Å; M82-T247 PolarHBondContact SD-OG1 3.45Å; M82-T247 VanDerWaalsContact SD-OG1 3.36Å; M82-W287 HydrophobicContact CB-CD2 4.25Å; M82-W287 HydrophobicContact CB-CE3 3.6Å; M82-W287 HydrophobicContact CB-CH2 4.48Å; M82-W287 HydrophobicContact CB-CZ3 3.73Å; M82-W287 HydrophobicContact CE-CB 3.98Å; M82-W287 HydrophobicContact CE-CG 4.44Å; M82-W287 HydrophobicContact CG-CE3 4.49Å; M82-L288 HydrophobicContact CE-CB 3.6Å; M82-L288 HydrophobicContact CE-CD1 4.18Å; M82-L288 HydrophobicContact SD-CD1 4.42Å
83G87.4Confident88.7Confident0 Ų042 Ų420%021%0.21CC..Hα-helixtrans-61.1-47.5-179.100000112.8T79 F80 N87T79-G83 PolarHBondContact O-N 2.92Å; F80-G83 PolarHBondContact O-N 2.68Å; G83-N87 WeakPolarHBondContact O-CB 3.39Å; G83-N87 PolarHBondContact O-N 3.44Å
84F90.6Very high88.8Confident117 Ų11742.1 Ų42.151%0.51321%0.212SC..Hα-helixtrans-62.6-43.4175-81.7-71.1000112.1F80 Q88F80-F84 VanDerWaalsContact O-CD2 3.23Å; F80-F84 WeakPolarHBondContact O-CD2 3.47Å; F80-F84 PolarHBondContact O-N 3.28Å; F84-Q88 VanDerWaalsContact O-CG 3.26Å; F84-Q88 WeakPolarHBondContact O-CG 3.49Å; F84-Q88 PolarHBondContact O-N 2.85Å; F84-Q88 VanDerWaalsContact O-N 3.12Å
85F93.5Very high89.4Confident4 Ų437.7 Ų37.72%0.01819%0.192CC..Hα-helixtrans-62.8-54.1-179.4-180-115.6000112I81 M82 N87 Q88 V89 L235 Y239 T240 V243 L288 A291 I295I81-F85 WeakPolarHBondContact O-CB 3.33Å; I81-F85 PolarHBondContact O-N 2.95Å; I81-F85 VanDerWaalsContact O-N 3.09Å; M82-F85 PolarHBondContact O-N 2.86Å; F85-N87 VanDerWaalsContact C-N 3.29Å; F85-N87 PolarHBondContact O-N 2.9Å; F85-Q88 PolarHBondContact O-N 3.42Å; F85-Q88 VanDerWaalsContact O-N 3.14Å; F85-V89 HydrophobicContact CD1-CG2 4.3Å; F85-V89 HydrophobicContact CD2-CG2 4.15Å; F85-V89 HydrophobicContact CE1-CG2 4.06Å; F85-V89 HydrophobicContact CE2-CG2 3.88Å; F85-V89 HydrophobicContact CG-CG2 4.36Å; F85-V89 HydrophobicContact CZ-CG2 3.83Å; F85-V89 WeakPolarHBondContact O-CG2 3.44Å; F85-V89 PolarHBondContact O-N 3.48Å; F85-L235 HydrophobicContact CE2-CD1 4.49Å; F85-Y239 HydrophobicContact CB-CE2 4.22Å; F85-Y239 HydrophobicContact CD2-CD1 4.24Å; F85-Y239 HydrophobicContact CD2-CD2 4.19Å; F85-Y239 HydrophobicContact CD2-CE1 4.15Å; F85-Y239 HydrophobicContact CD2-CE2 4.08Å; F85-Y239 HydrophobicContact CD2-CG 4.26Å; F85-Y239 PolarHBondContact N-OH 2.92Å; F85-T240 HydrophobicContact CZ-CG2 4.21Å; F85-V243 HydrophobicContact CB-CG1 4.25Å; F85-V243 HydrophobicContact CB-CG2 3.81Å; F85-V243 HydrophobicContact CD1-CB 4.28Å; F85-V243 HydrophobicContact CD1-CG1 3.75Å; F85-V243 HydrophobicContact CD1-CG2 4.25Å; F85-V243 HydrophobicContact CD2-CG2 3.97Å; F85-V243 HydrophobicContact CE1-CG1 4.3Å; F85-V243 HydrophobicContact CG-CB 4.29Å; F85-V243 HydrophobicContact CG-CG1 4.07Å; F85-V243 HydrophobicContact CG-CG2 3.76Å; F85-L288 HydrophobicContact CE1-CD1 4.47Å; F85-A291 HydrophobicContact CD1-CB 3.71Å; F85-A291 HydrophobicContact CE1-CB 3.39Å; F85-A291 HydrophobicContact CZ-CB 4.35Å; F85-I295 HydrophobicContact CZ-CD1 4.47Å
86V90.9Very high89.7Confident0 Ų032.9 Ų32.90%017%0.169CC..Hα-helixtrans-60.7-40.5-179.1175.60000111M82 Q88 V89 Y90 W287 V290 A291 Y613M82-V86 HydrophobicContact CE-CG2 4.46Å; M82-V86 WeakPolarHBondContact O-CB 3.2Å; M82-V86 VanDerWaalsContact O-CG2 3.23Å; M82-V86 WeakPolarHBondContact O-CG2 3.3Å; M82-V86 PolarHBondContact O-N 3.47Å; V86-Q88 VanDerWaalsContact C-N 3.34Å; V86-Q88 PolarHBondContact O-N 3.2Å; V86-V89 PolarHBondContact O-N 2.92Å; V86-Y90 WeakPolarHBondContact O-CB 3.33Å; V86-Y90 PolarHBondContact O-N 2.89Å; V86-W287 HydrophobicContact CG2-CD2 4.26Å; V86-W287 HydrophobicContact CG2-CG 3.95Å; V86-W287 WeakPolarHBondContact CG2-O 3.49Å; V86-V290 HydrophobicContact CG1-CG1 4.25Å; V86-A291 HydrophobicContact CG2-CB 3.94Å; V86-Y613 HydrophobicContact CG1-CE1 4.49Å
87N89.5Confident89.9Confident26 Ų2630.4 Ų30.414%0.13916%0.156CC..Hα-helixtrans-61.4-40.9177.8-173.364.6000112.6G83 F85 S91 F457 Q461G83-N87 WeakPolarHBondContact O-CB 3.39Å; G83-N87 PolarHBondContact O-N 3.44Å; F85-N87 VanDerWaalsContact C-N 3.29Å; F85-N87 PolarHBondContact O-N 2.9Å; N87-S91 WeakPolarHBondContact O-CB 3.35Å; N87-S91 PolarHBondContact O-N 3.29Å; N87-S91 PolarHBondContact O-OG 3Å; N87-F457 HydrophobicContact CB-CD1 4.03Å; N87-F457 HydrophobicContact CB-CE1 4.23Å; N87-Q461 PolarHBondContact OD1-NE2 3.38Å
88Q91.6Very high90.1Very high103 Ų10332 Ų3248%0.48116%0.156SC..Hα-helixtrans-70.9-41.6176.8-67.5-69.951.800112.1F84 F85 V86 S91 R92F84-Q88 VanDerWaalsContact O-CG 3.26Å; F84-Q88 WeakPolarHBondContact O-CG 3.49Å; F84-Q88 PolarHBondContact O-N 2.85Å; F84-Q88 VanDerWaalsContact O-N 3.12Å; F85-Q88 PolarHBondContact O-N 3.42Å; F85-Q88 VanDerWaalsContact O-N 3.14Å; V86-Q88 VanDerWaalsContact C-N 3.34Å; V86-Q88 PolarHBondContact O-N 3.2Å; Q88-S91 PolarHBondContact O-N 3.19Å; Q88-R92 WeakPolarHBondContact O-CB 3.46Å; Q88-R92 PolarHBondContact O-N 3.28Å
89V93.5Very high90.2Very high1 Ų132.7 Ų32.71%0.00616%0.161CC..Hα-helixtrans-60.4-49.8175.7179.90000110.3F85 V86 S91 R92 W93 L235 A291 L294 I295F85-V89 HydrophobicContact CD1-CG2 4.3Å; F85-V89 HydrophobicContact CD2-CG2 4.15Å; F85-V89 HydrophobicContact CE1-CG2 4.06Å; F85-V89 HydrophobicContact CE2-CG2 3.88Å; F85-V89 HydrophobicContact CG-CG2 4.36Å; F85-V89 HydrophobicContact CZ-CG2 3.83Å; F85-V89 WeakPolarHBondContact O-CG2 3.44Å; F85-V89 PolarHBondContact O-N 3.48Å; V86-V89 PolarHBondContact O-N 2.92Å; V89-S91 VanDerWaalsContact C-N 3.33Å; V89-S91 PolarHBondContact O-N 3.5Å; V89-R92 WeakPolarHBondContact O-CB 3.43Å; V89-R92 PolarHBondContact O-N 3.49Å; V89-W93 WeakPolarHBondContact O-CB 3.43Å; V89-W93 PolarHBondContact O-N 3.32Å; V89-L235 HydrophobicContact CB-CD1 4.4Å; V89-L235 HydrophobicContact CG2-CD1 3.6Å; V89-A291 HydrophobicContact CB-CB 4.39Å; V89-A291 HydrophobicContact CG1-CB 4.46Å; V89-A291 WeakPolarHBondContact CG1-O 3.47Å; V89-A291 HydrophobicContact CG2-CB 4.06Å; V89-L294 HydrophobicContact CG1-CB 3.68Å; V89-I295 HydrophobicContact CG1-CB 4.18Å
90Y90.7Very high90.5Very high5 Ų532.1 Ų32.12%0.0216%0.157CC..Hα-helixtrans-60.6-42.2178.3179.7-89.9000112.2V86 R92 W93 S94 L294 Q461 V609 Y613V86-Y90 WeakPolarHBondContact O-CB 3.33Å; V86-Y90 PolarHBondContact O-N 2.89Å; Y90-R92 VanDerWaalsContact C-N 3.29Å; Y90-R92 PolarHBondContact O-N 2.99Å; Y90-W93 HydrophobicContact CD2-CE3 4.26Å; Y90-W93 HydrophobicContact CE2-CE3 4.05Å; Y90-W93 AromaticContact CE2-CZ3 3.99Å; Y90-W93 HydrophobicContact CE2-CZ3 3.99Å; Y90-W93 PolarHBondContact O-N 2.98Å; Y90-S94 WeakPolarHBondContact O-CB 3.38Å; Y90-S94 PolarHBondContact O-N 3.31Å; Y90-L294 HydrophobicContact CD2-CD1 4.16Å; Y90-Q461 HydrophobicContact CD1-CB 4.21Å; Y90-Q461 VanDerWaalsContact CD1-CD 3.41Å; Y90-Q461 HydrophobicContact CD1-CG 3.83Å; Y90-Q461 HydrophobicContact CE1-CB 3.89Å; Y90-Q461 HydrophobicContact CE1-CG 4.01Å; Y90-V609 HydrophobicContact CE2-CG1 4.4Å; Y90-Y613 HydrophobicContact CD2-CD1 4.34Å; Y90-Y613 HydrophobicContact CD2-CE1 4.42Å
91S90.9Very high90.6Very high40 Ų4027.4 Ų27.428%0.2814%0.136SC..Hα-helixtrans-61.2-40.5177.5-63.10000111.6N87 Q88 V89 S95N87-S91 WeakPolarHBondContact O-CB 3.35Å; N87-S91 PolarHBondContact O-N 3.29Å; N87-S91 PolarHBondContact O-OG 3Å; Q88-S91 PolarHBondContact O-N 3.19Å; V89-S91 VanDerWaalsContact C-N 3.33Å; V89-S91 PolarHBondContact O-N 3.5Å; S91-S95 PolarHBondContact O-N 3.1Å; S91-S95 VanDerWaalsContact O-N 3.11Å; S91-S95 PolarHBondContact O-OG 3.48Å
92R91.5Very high90.7Very high41 Ų4128.1 Ų28.116%0.15514%0.136CC..Hα-helixtrans-69.3-43.8175.4-179.8179.9171.499.74.8112.6Q88 V89 Y90 S94 S95 N96 Y230 I233Q88-R92 WeakPolarHBondContact O-CB 3.46Å; Q88-R92 PolarHBondContact O-N 3.28Å; V89-R92 WeakPolarHBondContact O-CB 3.43Å; V89-R92 PolarHBondContact O-N 3.49Å; Y90-R92 VanDerWaalsContact C-N 3.29Å; Y90-R92 PolarHBondContact O-N 2.99Å; R92-S94 VanDerWaalsContact C-N 3.3Å; R92-S94 PolarHBondContact O-N 3.35Å; R92-S95 PolarHBondContact O-N 3.09Å; R92-S95 VanDerWaalsContact O-N 3.12Å; R92-N96 PolarHBondContact O-N 3.26Å; R92-N96 PolarHBondContact O-ND2 3.41Å; R92-Y230 HydrophobicContact CG-CD1 4.2Å; R92-Y230 HydrophobicContact CG-CE1 4.18Å; R92-Y230 VanDerWaalsContact NH2-C 3.33Å; R92-Y230 PolarHBondContact NH2-O 2.88Å; R92-I233 VanDerWaalsContact CZ-O 3.31Å; R92-I233 PolarHBondContact NH1-O 3.35Å; R92-I233 PolarHBondContact NH2-O 3.14Å
93W92.1Very high90.8Very high5 Ų528.1 Ų28.12%0.01914%0.136CC..Hα-helixtrans-54.9-48.1173.1174.195000110.7V89 Y90 S95 N96 F97 L294 F305 V607 P608 P610V89-W93 WeakPolarHBondContact O-CB 3.43Å; V89-W93 PolarHBondContact O-N 3.32Å; Y90-W93 HydrophobicContact CD2-CE3 4.26Å; Y90-W93 HydrophobicContact CE2-CE3 4.05Å; Y90-W93 AromaticContact CE2-CZ3 3.99Å; Y90-W93 HydrophobicContact CE2-CZ3 3.99Å; Y90-W93 PolarHBondContact O-N 2.98Å; W93-S95 VanDerWaalsContact C-N 3.28Å; W93-S95 PolarHBondContact O-N 2.97Å; W93-N96 PolarHBondContact O-N 3.48Å; W93-F97 PolarHBondContact O-N 3.25Å; W93-L294 HydrophobicContact CB-CB 4.26Å; W93-L294 VanDerWaalsContact CD1-CD2 3.48Å; W93-L294 HydrophobicContact CD2-CD2 4.07Å; W93-L294 HydrophobicContact CG-CB 4.25Å; W93-L294 HydrophobicContact CG-CD2 3.9Å; W93-F305 HydrophobicContact CD2-CE1 4.43Å; W93-F305 HydrophobicContact CD2-CZ 4.2Å; W93-F305 AromaticContact CE2-CE1 3.54Å; W93-F305 AromaticContact CE2-CZ 3.7Å; W93-F305 HydrophobicContact CG-CZ 4.36Å; W93-F305 HydrophobicContact CH2-CE1 4.47Å; W93-F305 AromaticContact CZ2-CE1 3.57Å; W93-F305 HydrophobicContact CZ2-CE1 3.57Å; W93-F305 HydrophobicContact CZ2-CZ 4.15Å; W93-F305 AromaticContact NE1-CE1 3.54Å; W93-F305 AromaticContact NE1-CZ 3.57Å; W93-V607 HydrophobicContact CH2-CG1 3.72Å; W93-V607 HydrophobicContact CZ2-CG1 3.73Å; W93-P608 WeakPolarHBondContact CH2-O 3.21Å; W93-P610 HydrophobicContact CH2-CG 4.42Å; W93-P610 HydrophobicContact CZ2-CG 4.32Å
94S89.9Confident91Very high19 Ų1928.2 Ų28.213%0.13314%0.137CC..Hα-helixtrans-60.4-36.1176.7-170.70000112.6Y90 R92 K98Y90-S94 WeakPolarHBondContact O-CB 3.38Å; Y90-S94 PolarHBondContact O-N 3.31Å; R92-S94 VanDerWaalsContact C-N 3.3Å; R92-S94 PolarHBondContact O-N 3.35Å; S94-K98 WeakPolarHBondContact O-CD 3.45Å; S94-K98 WeakPolarHBondContact O-CE 3.48Å; S94-K98 WeakPolarHBondContact O-CG 3.32Å; S94-K98 PolarHBondContact O-N 3.39Å; S94-K98 VanDerWaalsContact OG-CE 3.25Å; S94-K98 WeakPolarHBondContact OG-CE 3.48Å; S94-K98 PolarHBondContact OG-NZ 2.98Å
95S91.3Very high90.9Very high31 Ų3123.3 Ų23.322%0.21712%0.117CC..Hα-helixtrans-73.7-40.8177.3-66.70000112.6S91 R92 W93 F97 K98 S99 Y230S91-S95 PolarHBondContact O-N 3.1Å; S91-S95 VanDerWaalsContact O-N 3.11Å; S91-S95 PolarHBondContact O-OG 3.48Å; R92-S95 PolarHBondContact O-N 3.09Å; R92-S95 VanDerWaalsContact O-N 3.12Å; W93-S95 VanDerWaalsContact C-N 3.28Å; W93-S95 PolarHBondContact O-N 2.97Å; S95-F97 VanDerWaalsContact C-N 3.31Å; S95-F97 PolarHBondContact O-N 2.69Å; S95-K98 PolarHBondContact O-N 3.24Å; S95-K98 VanDerWaalsContact O-N 3.12Å; S95-S99 PolarHBondContact O-N 3.38Å; S95-S99 VanDerWaalsContact O-N 3.1Å; S95-S99 PolarHBondContact O-OG 3.17Å; S95-Y230 VanDerWaalsContact CB-OH 3.25Å; S95-Y230 WeakPolarHBondContact CB-OH 3.24Å
96N91.3Very high90.9Very high6 Ų623.2 Ų23.23%0.03212%0.116CC..Hα-helixtrans-57.4-45173.1-82.4-82.3000111.6R92 W93 K98 S99 L100 Y230 P297 F298 F305R92-N96 PolarHBondContact O-N 3.26Å; R92-N96 PolarHBondContact O-ND2 3.41Å; W93-N96 PolarHBondContact O-N 3.48Å; N96-K98 VanDerWaalsContact C-N 3.3Å; N96-K98 PolarHBondContact O-N 2.85Å; N96-S99 PolarHBondContact O-N 3.26Å; N96-S99 VanDerWaalsContact O-N 3.11Å; N96-L100 PolarHBondContact O-N 3.35Å; N96-Y230 WeakPolarHBondContact OD1-CB 3.43Å; N96-P297 HydrophobicContact CB-CG 4.13Å; N96-F298 HydrophobicContact CB-CE2 4.2Å; N96-F298 HydrophobicContact CB-CZ 4.15Å; N96-F305 HydrophobicContact CB-CE2 4.25Å
97F90.1Very high91.1Very high12 Ų1223.2 Ų23.25%0.05312%0.116CC..Hα-helixtrans-55.9-44.1175-176.5-116.8000112.7W93 S95 S99 L100 F305 L603 V607W93-F97 PolarHBondContact O-N 3.25Å; S95-F97 VanDerWaalsContact C-N 3.31Å; S95-F97 PolarHBondContact O-N 2.69Å; F97-S99 VanDerWaalsContact C-N 3.25Å; F97-S99 PolarHBondContact O-N 2.84Å; F97-L100 HydrophobicContact CD2-CD1 3.79Å; F97-L100 HydrophobicContact CE2-CD1 4.23Å; F97-L100 WeakPolarHBondContact O-CB 3.35Å; F97-L100 PolarHBondContact O-N 3.18Å; F97-F305 HydrophobicContact CB-CE1 4.02Å; F97-F305 HydrophobicContact CB-CE2 3.93Å; F97-F305 HydrophobicContact CB-CZ 3.47Å; F97-F305 VanDerWaalsContact CB-CZ 3.47Å; F97-F305 AromaticContact CD2-CD1 3.98Å; F97-F305 HydrophobicContact CD2-CD1 3.98Å; F97-F305 AromaticContact CD2-CE1 3.72Å; F97-F305 HydrophobicContact CD2-CE1 3.72Å; F97-F305 HydrophobicContact CD2-CE2 4.34Å; F97-F305 HydrophobicContact CD2-CG 4.43Å; F97-F305 AromaticContact CD2-CZ 3.95Å; F97-F305 HydrophobicContact CD2-CZ 3.95Å; F97-F305 HydrophobicContact CG-CE1 4.19Å; F97-F305 HydrophobicContact CG-CZ 4.13Å; F97-L603 HydrophobicContact CE1-CB 4.16Å; F97-L603 HydrophobicContact CZ-CB 3.81Å; F97-L603 WeakPolarHBondContact CZ-O 3.47Å; F97-V607 HydrophobicContact CD2-CB 4.32Å; F97-V607 HydrophobicContact CD2-CG1 4.26Å; F97-V607 HydrophobicContact CD2-CG2 4.17Å; F97-V607 HydrophobicContact CE1-CB 4.28Å; F97-V607 HydrophobicContact CE2-CB 3.7Å; F97-V607 HydrophobicContact CE2-CG1 4.13Å; F97-V607 HydrophobicContact CE2-CG2 3.32Å; F97-V607 HydrophobicContact CZ-CB 3.64Å; F97-V607 HydrophobicContact CZ-CG1 4.39Å; F97-V607 HydrophobicContact CZ-CG2 3.61Å
98K89Confident91.2Very high104 Ų10422 Ų2245%0.45211%0.11SC..Hα-helixtrans-68.2-25.2-179.6-66.8162.4-155.81540112.8S94 S95 N96S94-K98 WeakPolarHBondContact O-CD 3.45Å; S94-K98 WeakPolarHBondContact O-CE 3.48Å; S94-K98 WeakPolarHBondContact O-CG 3.32Å; S94-K98 PolarHBondContact O-N 3.39Å; S94-K98 VanDerWaalsContact OG-CE 3.25Å; S94-K98 WeakPolarHBondContact OG-CE 3.48Å; S94-K98 PolarHBondContact OG-NZ 2.98Å; S95-K98 PolarHBondContact O-N 3.24Å; S95-K98 VanDerWaalsContact O-N 3.12Å; N96-K98 VanDerWaalsContact C-N 3.3Å; N96-K98 PolarHBondContact O-N 2.85Å
99S91.2Very high91.1Very high16 Ų1617.5 Ų17.511%0.1129%0.089CC..Hα-helixtrans-85.2-9.2-178.4-64.10000113.5S95 N96 F97 S223 T226S95-S99 PolarHBondContact O-N 3.38Å; S95-S99 VanDerWaalsContact O-N 3.1Å; S95-S99 PolarHBondContact O-OG 3.17Å; N96-S99 PolarHBondContact O-N 3.26Å; N96-S99 VanDerWaalsContact O-N 3.11Å; F97-S99 VanDerWaalsContact C-N 3.25Å; F97-S99 PolarHBondContact O-N 2.84Å; S99-S223 WeakPolarHBondContact O-CB 3.27Å; S99-T226 WeakPolarHBondContact OG-CG2 3.34Å
100L92.8Very high91.1Very high2 Ų217.5 Ų17.51%0.019%0.089CC..SBendtrans-55.4131174.7-74.3168000111.1N96 F97 W102 L140 L227 F298 F305 I307 I310N96-L100 PolarHBondContact O-N 3.35Å; F97-L100 HydrophobicContact CD2-CD1 3.79Å; F97-L100 HydrophobicContact CE2-CD1 4.23Å; F97-L100 WeakPolarHBondContact O-CB 3.35Å; F97-L100 PolarHBondContact O-N 3.18Å; L100-W102 PolarHBondContact O-N 2.96Å; L100-W102 PolarHBondContact O-NE1 3.1Å; L100-L140 HydrophobicContact CD2-CD2 4.32Å; L100-L227 HydrophobicContact CD2-CD1 4.48Å; L100-F298 HydrophobicContact CD2-CE1 3.93Å; L100-F305 HydrophobicContact CD1-CD2 3.96Å; L100-F305 HydrophobicContact CD1-CE2 4.5Å; L100-F305 HydrophobicContact CD1-CG 4.28Å; L100-I307 HydrophobicContact CD2-CD1 3.8Å; L100-I310 HydrophobicContact CD1-CD1 3.75Å; L100-I310 HydrophobicContact CD2-CD1 4.24Å; L100-I310 HydrophobicContact CG-CD1 4.46Å
101P88.1Confident91.2Very high1 Ų117.3 Ų17.31%0.0069%0.088CC..  trans-75.2120.9-174.728.7-33.9000111.7C136 V224 N314P101-C136 VanDerWaalsContact CB-SG 3.58Å; P101-C136 HydrophobicContact CG-CB 3.99Å; P101-V224 HydrophobicContact CB-CG1 4.36Å; P101-V224 HydrophobicContact CG-CG1 4.32Å; P101-N314 PolarHBondContact O-ND2 3.01Å
102W89.7Confident91Very high58 Ų5815.7 Ų15.722%0.228%0.076CC..  trans-112110.8172.6-63.993.9000109.6L100 I310 L603 W606L100-W102 PolarHBondContact O-N 2.96Å; L100-W102 PolarHBondContact O-NE1 3.1Å; W102-I310 HydrophobicContact CH2-CD1 4.49Å; W102-I310 HydrophobicContact CH2-CG1 4.01Å; W102-I310 HydrophobicContact CZ2-CD1 4.24Å; W102-I310 HydrophobicContact CZ2-CG1 4.24Å; W102-L603 HydrophobicContact CD2-CD1 3.85Å; W102-L603 HydrophobicContact CG-CD1 4.26Å; W102-L603 HydrophobicContact CH2-CD1 4.37Å; W102-L603 HydrophobicContact CH2-CD2 3.34Å; W102-L603 HydrophobicContact CH2-CG 4.42Å; W102-L603 HydrophobicContact CZ2-CD1 3.64Å; W102-L603 HydrophobicContact CZ2-CD2 3.15Å; W102-L603 HydrophobicContact CZ2-CG 4.01Å; W102-L603 HydrophobicContact CZ3-CD2 4.11Å; W102-L603 VanDerWaalsContact NE1-CD1 3.32Å; W102-W606 HydrophobicContact CH2-CZ3 4.34Å
103I92Very high91Very high0 Ų013.7 Ų13.70%07%0.069CC..  trans-93.7-3.6-163.563.2164.8000114.8S105 M106 M107 I132 N133 N314I103-S105 PolarHBondContact O-N 3.48Å; I103-M106 CarbonylContact O-C 3.46Å; I103-M106 WeakPolarHBondContact O-CA 3.43Å; I103-M106 VanDerWaalsContact O-CB 3.25Å; I103-M106 WeakPolarHBondContact O-CB 3.39Å; I103-M106 PolarHBondContact O-N 3.37Å; I103-M107 HydrophobicContact CB-CE 4.24Å; I103-M107 HydrophobicContact CB-CG 4.42Å; I103-M107 HydrophobicContact CD1-CE 4.05Å; I103-M107 HydrophobicContact CD1-CG 4.01Å; I103-M107 HydrophobicContact CD1-SD 4.49Å; I103-M107 HydrophobicContact CG1-CG 4.17Å; I103-M107 WeakPolarHBondContact O-CG 3.09Å; I103-M107 PolarHBondContact O-N 2.84Å; I103-I132 HydrophobicContact CB-CG2 4.45Å; I103-I132 HydrophobicContact CG2-CG2 3.91Å; I103-N133 WeakPolarHBondContact CD1-ND2 3.08Å; I103-N133 WeakPolarHBondContact CD1-OD1 3.48Å; I103-N314 HydrophobicContact CD1-CB 3.87Å; I103-N314 WeakPolarHBondContact CD1-O 3.49Å; I103-N314 HydrophobicContact CG1-CB 3.91Å
104D90.4Very high91Very high2 Ų213.6 Ų13.61%0.0117%0.068CC..Hα-helixtrans-67.5-34.7-168.68.4-22.3000113.1M106 M107 I108 R313 V317 M321 R595D104-M106 VanDerWaalsContact C-N 3.26Å; D104-M106 PolarHBondContact O-N 3.25Å; D104-M107 PolarHBondContact O-N 2.86Å; D104-I108 VanDerWaalsContact O-CG1 3.25Å; D104-I108 WeakPolarHBondContact O-CG1 3.13Å; D104-I108 PolarHBondContact O-N 3.08Å; D104-R313 IonicContact OD1-CZ 3.72Å; D104-R313 IonicContact OD1-NH1 3.3Å; D104-R313 PolarHBondContact OD1-NH1 2.7Å; D104-R313 IonicContact OD1-NH2 2.9Å; D104-R313 PolarHBondContact OD1-NH2 3.46Å; D104-R313 IonicContact OD2-CZ 2.62Å; D104-R313 IonicContact OD2-NH1 2.65Å; D104-R313 IonicContact OD2-NH2 3.65Å; D104-R313 PolarHBondContact OD2-NH2 3.12Å; D104-V317 HydrophobicContact CB-CG1 4.17Å; D104-M321 HydrophobicContact CB-CE 3.5Å; D104-M321 VanDerWaalsContact CB-CE 3.5Å; D104-M321 HydrophobicContact CB-SD 3.64Å; D104-R595 IonicContact OD1-NH1 3.56Å; D104-R595 PolarHBondContact OD1-NH1 3.48Å; D104-R595 IonicContact OD2-NH1 3.29Å; D104-R595 PolarHBondContact OD2-NH1 3.11Å
105S89.3Confident91.1Very high13 Ų1314.6 Ų14.69%0.0917%0.071CC..Hα-helixtrans-60.4-38.4169.7-85.90000112.2I103 R109 R595I103-S105 PolarHBondContact O-N 3.48Å; S105-R109 WeakPolarHBondContact O-CB 3.46Å; S105-R109 PolarHBondContact O-N 3.31Å; S105-R109 VanDerWaalsContact O-N 3.14Å; S105-R595 PolarHBondContact OG-NE 3.45Å; S105-R595 PolarHBondContact OG-NH2 3.37Å
106M92.9Very high90.9Very high2 Ų213.8 Ų13.81%0.017%0.067CC..Hα-helixtrans-67.4-40.6176.117262.7-168.100110.6I103 D104 R109 A110 L128 I132 L213 E216 I217I103-M106 CarbonylContact O-C 3.46Å; I103-M106 WeakPolarHBondContact O-CA 3.43Å; I103-M106 VanDerWaalsContact O-CB 3.25Å; I103-M106 WeakPolarHBondContact O-CB 3.39Å; I103-M106 PolarHBondContact O-N 3.37Å; D104-M106 VanDerWaalsContact C-N 3.26Å; D104-M106 PolarHBondContact O-N 3.25Å; M106-R109 PolarHBondContact O-N 2.82Å; M106-A110 WeakPolarHBondContact O-CB 3.33Å; M106-A110 PolarHBondContact O-N 2.83Å; M106-L128 HydrophobicContact CE-CD1 3.96Å; M106-L128 HydrophobicContact CE-CD2 3.79Å; M106-L128 HydrophobicContact CE-CG 3.91Å; M106-I132 HydrophobicContact CE-CD1 3.99Å; M106-I132 HydrophobicContact CE-CG1 3.98Å; M106-I132 HydrophobicContact CG-CG1 4.37Å; M106-I132 HydrophobicContact CG-CG2 4.44Å; M106-L213 HydrophobicContact CE-CD1 3.62Å; M106-L213 HydrophobicContact CE-CG 4.17Å; M106-L213 HydrophobicContact SD-CD1 3.87Å; M106-E216 HydrophobicContact CB-CB 4.07Å; M106-E216 HydrophobicContact CG-CB 4.3Å; M106-E216 HydrophobicContact SD-CB 3.33Å; M106-E216 WeakPolarHBondContact SD-CB 3.29Å; M106-E216 HydrophobicContact SD-CG 4.43Å; M106-I217 HydrophobicContact CE-CD1 4.12Å; M106-I217 HydrophobicContact CE-CG1 3.47Å; M106-I217 VanDerWaalsContact CE-CG1 3.47Å; M106-I217 HydrophobicContact SD-CG1 3.99Å
107M95.6Very high90.7Very high0 Ų021.1 Ų21.10%011%0.105CC..Hα-helixtrans-72.9-41.2-178.1-62.4-56.3130.400112.9I103 D104 R109 A110 A111 A129 I132 M321 V322I103-M107 HydrophobicContact CB-CE 4.24Å; I103-M107 HydrophobicContact CB-CG 4.42Å; I103-M107 HydrophobicContact CD1-CE 4.05Å; I103-M107 HydrophobicContact CD1-CG 4.01Å; I103-M107 HydrophobicContact CD1-SD 4.49Å; I103-M107 HydrophobicContact CG1-CG 4.17Å; I103-M107 WeakPolarHBondContact O-CG 3.09Å; I103-M107 PolarHBondContact O-N 2.84Å; D104-M107 PolarHBondContact O-N 2.86Å; M107-R109 VanDerWaalsContact C-N 3.25Å; M107-R109 PolarHBondContact O-N 2.89Å; M107-A110 PolarHBondContact O-N 2.9Å; M107-A111 WeakPolarHBondContact O-CB 3.3Å; M107-A111 PolarHBondContact O-N 3.11Å; M107-A129 HydrophobicContact CE-CB 4.32Å; M107-A129 HydrophobicContact SD-CB 3.48Å; M107-A129 WeakPolarHBondContact SD-CB 3.14Å; M107-I132 HydrophobicContact CE-CB 3.85Å; M107-I132 HydrophobicContact CE-CG1 4.08Å; M107-I132 HydrophobicContact CE-CG2 3.85Å; M107-M321 HydrophobicContact CB-CB 4.03Å; M107-M321 HydrophobicContact CB-SD 3.83Å; M107-V322 HydrophobicContact CB-CG1 4.01Å; M107-V322 HydrophobicContact SD-CG1 3.96Å
108I90.6Very high90.9Very high1 Ų123.8 Ų23.81%0.00512%0.121CC..Hα-helixtrans-57.7-44.5169.6-64.3164.2000109.4D104 A111 I112 M321 C566 L592 R595D104-I108 VanDerWaalsContact O-CG1 3.25Å; D104-I108 WeakPolarHBondContact O-CG1 3.13Å; D104-I108 PolarHBondContact O-N 3.08Å; I108-A111 PolarHBondContact O-N 3.36Å; I108-I112 WeakPolarHBondContact O-CG1 3.49Å; I108-I112 WeakPolarHBondContact O-CG2 3.17Å; I108-I112 PolarHBondContact O-N 3.07Å; I108-M321 HydrophobicContact CD1-CE 4.05Å; I108-M321 HydrophobicContact CD1-SD 4.45Å; I108-M321 HydrophobicContact CG1-CE 3.92Å; I108-M321 HydrophobicContact CG1-SD 3.75Å; I108-C566 HydrophobicContact CG2-CB 3.85Å; I108-C566 WeakPolarHBondContact CG2-SG 3.46Å; I108-L592 HydrophobicContact CB-CD2 3.78Å; I108-L592 HydrophobicContact CD1-CD2 3.69Å; I108-L592 HydrophobicContact CG1-CD2 4.34Å; I108-L592 HydrophobicContact CG2-CD2 3.66Å; I108-R595 HydrophobicContact CD1-CG 4.32Å
109R91Very high91.1Very high9 Ų924.6 Ų24.63%0.03413%0.126CC..Hα-helixtrans-66-39.8179.4-162.5177.7-61.2-101.513.6112.4S105 M106 M107 A111 I112 S113 K212 L213 E216 N589S105-R109 WeakPolarHBondContact O-CB 3.46Å; S105-R109 PolarHBondContact O-N 3.31Å; S105-R109 VanDerWaalsContact O-N 3.14Å; M106-R109 PolarHBondContact O-N 2.82Å; M107-R109 VanDerWaalsContact C-N 3.25Å; M107-R109 PolarHBondContact O-N 2.89Å; R109-A111 VanDerWaalsContact C-N 3.34Å; R109-I112 HydrophobicContact CG-CD1 4.38Å; R109-I112 VanDerWaalsContact O-CG1 3.25Å; R109-I112 WeakPolarHBondContact O-CG1 3.28Å; R109-I112 PolarHBondContact O-N 3.28Å; R109-S113 VanDerWaalsContact O-CB 3.25Å; R109-S113 WeakPolarHBondContact O-CB 3.29Å; R109-S113 PolarHBondContact O-N 2.82Å; R109-S113 PolarHBondContact O-OG 3.16Å; R109-K212 VanDerWaalsContact CD-O 3.27Å; R109-K212 WeakPolarHBondContact CD-O 3.32Å; R109-L213 HydrophobicContact CB-CD1 4.31Å; R109-L213 HydrophobicContact CG-CD1 4.22Å; R109-E216 HydrophobicContact CB-CG 4.31Å; R109-E216 VanDerWaalsContact CD-CG 3.49Å; R109-E216 IonicContact CZ-OE1 3.09Å; R109-E216 IonicContact NE-OE1 2.95Å; R109-E216 PolarHBondContact NE-OE1 3.41Å; R109-E216 IonicContact NH2-OE1 3.98Å; R109-E216 PolarHBondContact NH2-OE1 3.34Å; R109-N589 PolarHBondContact NH1-OD1 2.83Å; R109-N589 PolarHBondContact NH2-OD1 3.34Å
110A93.6Very high91.2Very high0 Ų027.4 Ų27.40%013%0.134CC..Hα-helixtrans-61.7-44.5173.600000111.4M106 M107 I112 S113 I114 L128 L213 V322M106-A110 WeakPolarHBondContact O-CB 3.33Å; M106-A110 PolarHBondContact O-N 2.83Å; M107-A110 PolarHBondContact O-N 2.9Å; A110-I112 PolarHBondContact O-N 3.27Å; A110-S113 PolarHBondContact O-N 3.14Å; A110-I114 WeakPolarHBondContact O-CB 3.31Å; A110-I114 PolarHBondContact O-N 3.16Å; A110-I114 VanDerWaalsContact O-N 3.1Å; A110-L128 HydrophobicContact CB-CD2 3.78Å; A110-L213 HydrophobicContact CB-CD1 4.12Å; A110-V322 HydrophobicContact CB-CG1 4.29Å
111A92.2Very high91.2Very high1 Ų127.3 Ų27.31%0.00813%0.134CC..Hα-helixtrans-61.6-42.8178.100000111.8M107 I108 R109 V322 Y326M107-A111 WeakPolarHBondContact O-CB 3.3Å; M107-A111 PolarHBondContact O-N 3.11Å; I108-A111 PolarHBondContact O-N 3.36Å; R109-A111 VanDerWaalsContact C-N 3.34Å; A111-V322 HydrophobicContact CB-CG1 4.49Å; A111-Y326 HydrophobicContact CB-CD2 4.33Å; A111-Y326 VanDerWaalsContact O-CD2 3.26Å; A111-Y326 WeakPolarHBondContact O-CD2 3.35Å; A111-Y326 WeakPolarHBondContact O-CE2 3.5Å
112I86.2Confident91.5Very high6 Ų631 Ų313%0.03115%0.147CC..Hα-helixtrans-80.1-24.3-178.966.4-179.4000114.5I108 R109 A110 H115 M209 C566 M588I108-I112 WeakPolarHBondContact O-CG1 3.49Å; I108-I112 WeakPolarHBondContact O-CG2 3.17Å; I108-I112 PolarHBondContact O-N 3.07Å; R109-I112 HydrophobicContact CG-CD1 4.38Å; R109-I112 VanDerWaalsContact O-CG1 3.25Å; R109-I112 WeakPolarHBondContact O-CG1 3.28Å; R109-I112 PolarHBondContact O-N 3.28Å; A110-I112 PolarHBondContact O-N 3.27Å; I112-H115 PolarHBondContact O-CE1 2.94Å; I112-M209 HydrophobicContact CD1-CE 4.34Å; I112-M209 HydrophobicContact CG1-CE 4.29Å; I112-C566 HydrophobicContact CG2-CB 4.17Å; I112-M588 HydrophobicContact CB-CE 4.41Å; I112-M588 HydrophobicContact CD1-CE 3.61Å; I112-M588 HydrophobicContact CD1-CG 3.32Å; I112-M588 HydrophobicContact CD1-SD 3.48Å; I112-M588 WeakPolarHBondContact CD1-SD 3.35Å; I112-M588 HydrophobicContact CG2-CE 4Å; I112-M588 HydrophobicContact CG2-SD 4.41Å
113S91Very high91.8Very high0 Ų032 Ų320%016%0.157CC..Hα-helixtrans-93.1-31.7-173.1-62.20000113.3R109 A110 M209R109-S113 VanDerWaalsContact O-CB 3.25Å; R109-S113 WeakPolarHBondContact O-CB 3.29Å; R109-S113 PolarHBondContact O-N 2.82Å; R109-S113 PolarHBondContact O-OG 3.16Å; A110-S113 PolarHBondContact O-N 3.14Å; S113-M209 VanDerWaalsContact OG-CE 3.22Å; S113-M209 WeakPolarHBondContact OG-CE 3.31Å
114I93.8Very high92Very high2 Ų232.1 Ų32.11%0.0116%0.157CC..SBendtrans-99.2105.9-176.5-59.8174.8000108.7A110 L124 R125 L128 I204 L213A110-I114 WeakPolarHBondContact O-CB 3.31Å; A110-I114 PolarHBondContact O-N 3.16Å; A110-I114 VanDerWaalsContact O-N 3.1Å; I114-L124 HydrophobicContact CG2-CB 3.82Å; I114-L124 HydrophobicContact CG2-CD1 4.22Å; I114-R125 HydrophobicContact CB-CG 3.75Å; I114-R125 HydrophobicContact CD1-CG 4.47Å; I114-R125 HydrophobicContact CG2-CG 3.79Å; I114-R125 PolarHBondContact O-NH1 3.37Å; I114-L128 HydrophobicContact CD1-CD2 3.59Å; I114-I204 HydrophobicContact CG1-CD1 4.33Å; I114-I204 HydrophobicContact CG1-CG1 4.17Å; I114-L213 HydrophobicContact CD1-CD2 4.04Å; I114-L213 HydrophobicContact CG1-CD2 4.16Å
115H90.9Very high92.3Very high41 Ų4132.2 Ų32.219%0.1916%0.157CC..  trans-85154.1-176-59.9-60.8000113.3I112 R203 D205 Y326I112-H115 PolarHBondContact O-CE1 2.94Å; H115-R203 WeakPolarHBondContact CB-O 3.33Å; H115-R203 PolarHBondContact CD2-O 3.07Å; H115-R203 PolarHBondContact N-O 3.01Å; H115-D205 IonicContact CD2-OD2 3.83Å; H115-D205 IonicContact CE1-OD2 3.7Å; H115-D205 IonicContact NE2-OD1 3.74Å; H115-D205 IonicContact NE2-OD2 3.34Å; H115-D205 PolarHBondContact NE2-OD2 2.93Å; H115-Y326 WeakPolarHBondContact CA-OH 3.5Å
116G87.6Confident92.6Very high13 Ų1334.8 Ų34.813%0.13417%0.165CC..  trans130.5119.317500000111.7D118 R125 Y326G116-D118 VanDerWaalsContact C-N 3.31Å; G116-D118 VanDerWaalsContact CA-OD1 3.28Å; G116-D118 WeakPolarHBondContact CA-OD1 3.33Å; G116-R125 PolarHBondContact O-NH1 2.88Å; G116-R125 PolarHBondContact O-NH2 2.65Å; G116-Y326 PolarHBondContact N-OH 3.13Å
117L87.6Confident92.8Very high160 Ų16035.4 Ų35.484%0.83817%0.169SC*.SBendtrans-86.2-9.3170.7-68.4169.1000112Y326L117-Y326 HydrophobicContact CD2-CD1 4.02Å; L117-Y326 HydrophobicContact CD2-CE1 3.67Å; L117-Y326 HydrophobicContact CG-CE1 4.36Å
118D93.1Very high92.9Very high69 Ų6935.4 Ų35.437%0.36917%0.169SC..SBendtrans-78.1166174.963.5-39.3000112G116 R120 G121 R122 R203G116-D118 VanDerWaalsContact C-N 3.31Å; G116-D118 VanDerWaalsContact CA-OD1 3.28Å; G116-D118 WeakPolarHBondContact CA-OD1 3.33Å; D118-R120 PolarHBondContact O-N 3.38Å; D118-R120 VanDerWaalsContact O-N 3.15Å; D118-G121 PolarHBondContact O-N 3.35Å; D118-G121 VanDerWaalsContact O-N 3.11Å; D118-R122 PolarHBondContact O-N 3.41Å; D118-R122 VanDerWaalsContact O-N 3.11Å; D118-R203 IonicContact OD1-CZ 3.47Å; D118-R203 IonicContact OD1-NH1 3.52Å; D118-R203 PolarHBondContact OD1-NH1 2.68Å; D118-R203 IonicContact OD1-NH2 2.68Å; D118-R203 IonicContact OD2-CZ 3.52Å; D118-R203 IonicContact OD2-NH1 3.56Å; D118-R203 PolarHBondContact OD2-NH1 2.92Å; D118-R203 IonicContact OD2-NH2 3.55Å; D118-R203 PolarHBondContact OD2-NH2 2.77Å
119E92.6Very high93.2Very high120 Ų12035.3 Ų35.356%0.56117%0.169SC*.Hα-helixtrans-59.4-31.3-176.8-168.657.7-153.600112.3R122 L123E119-R122 PolarHBondContact O-N 3.14Å; E119-R122 IonicContact OE1-NH1 3.52Å; E119-R122 PolarHBondContact OE1-NH1 3.07Å; E119-R122 IonicContact OE2-NH1 2.73Å; E119-L123 WeakPolarHBondContact O-CB 3.44Å; E119-L123 PolarHBondContact O-N 3.28Å
120R95.1Very high93.5Very high76 Ų7636.3 Ų36.329%0.28717%0.172SC..Hα-helixtrans-65.7-45.9176.6-179.460-178.3173.14.1112.2D118 R122 L123 L124 E201D118-R120 PolarHBondContact O-N 3.38Å; D118-R120 VanDerWaalsContact O-N 3.15Å; R120-R122 VanDerWaalsContact C-N 3.33Å; R120-L123 PolarHBondContact O-N 3.44Å; R120-L124 WeakPolarHBondContact O-CG 3.32Å; R120-L124 PolarHBondContact O-N 3.29Å; R120-E201 IonicContact CZ-OE1 2.66Å; R120-E201 IonicContact CZ-OE2 3.32Å; R120-E201 IonicContact NE-OE1 3.32Å; R120-E201 IonicContact NE-OE2 2.82Å; R120-E201 PolarHBondContact NE-OE2 3.29Å; R120-E201 IonicContact NH2-OE1 3.72Å; R120-E201 PolarHBondContact NH2-OE1 3.14Å; R120-E201 IonicContact NH2-OE2 3.04Å; R120-E201 PolarHBondContact NH2-OE2 2.93Å
121G92.6Very high93.7Very high0 Ų037.9 Ų37.90%018%0.178CC..Hα-helixtrans-62.3-43.3176.700000111.6D118 L124 R125D118-G121 PolarHBondContact O-N 3.35Å; D118-G121 VanDerWaalsContact O-N 3.11Å; G121-L124 PolarHBondContact O-N 2.84Å; G121-R125 PolarHBondContact O-N 3.04Å; G121-R125 VanDerWaalsContact O-N 3.15Å; G121-R125 PolarHBondContact O-NH1 3.35Å
122R94.4Very high94Very high77 Ų7737.9 Ų37.929%0.29118%0.178SC..Hα-helixtrans-60.3-46174.1-178.2176.8176.2-96.4-2.6112.3D118 E119 R120 L124 R125 R126 D323D118-R122 PolarHBondContact O-N 3.41Å; D118-R122 VanDerWaalsContact O-N 3.11Å; E119-R122 PolarHBondContact O-N 3.14Å; E119-R122 IonicContact OE1-NH1 3.52Å; E119-R122 PolarHBondContact OE1-NH1 3.07Å; E119-R122 IonicContact OE2-NH1 2.73Å; R120-R122 VanDerWaalsContact C-N 3.33Å; R122-L124 PolarHBondContact O-N 3.36Å; R122-R125 PolarHBondContact O-N 2.99Å; R122-R126 HydrophobicContact CG-CG 4.33Å; R122-R126 WeakPolarHBondContact O-CB 3.48Å; R122-R126 WeakPolarHBondContact O-CG 3.39Å; R122-R126 PolarHBondContact O-N 3.31Å; R122-D323 WeakPolarHBondContact CD-OD1 3.41Å; R122-D323 IonicContact CZ-OD1 3.38Å; R122-D323 IonicContact CZ-OD2 2.73Å; R122-D323 VanDerWaalsContact CZ-OD2 3.31Å; R122-D323 VanDerWaalsContact NE-CG 3.3Å; R122-D323 IonicContact NE-OD1 3.25Å; R122-D323 PolarHBondContact NE-OD1 2.88Å; R122-D323 IonicContact NE-OD2 3.23Å; R122-D323 PolarHBondContact NE-OD2 3.43Å; R122-D323 IonicContact NH2-OD2 2.75Å; R122-D323 PolarHBondContact NH2-OD2 3.37Å
123L95Very high94.5Very high80 Ų8037.8 Ų37.842%0.41918%0.178SC..Hα-helixtrans-60-45.1178.4179.265.8000111.7E119 R120 T127E119-L123 WeakPolarHBondContact O-CB 3.44Å; E119-L123 PolarHBondContact O-N 3.28Å; R120-L123 PolarHBondContact O-N 3.44Å; L123-T127 WeakPolarHBondContact O-CB 3.34Å; L123-T127 PolarHBondContact O-N 2.97Å; L123-T127 PolarHBondContact O-OG1 2.84Å
124L97.1Very high94.8Very high2 Ų237.8 Ų37.81%0.0118%0.178CC..Hα-helixtrans-59.8-48177.3-73172.5000111.6I114 R120 G121 R122 L128 L194 A198 R203I114-L124 HydrophobicContact CG2-CB 3.82Å; I114-L124 HydrophobicContact CG2-CD1 4.22Å; R120-L124 WeakPolarHBondContact O-CG 3.32Å; R120-L124 PolarHBondContact O-N 3.29Å; G121-L124 PolarHBondContact O-N 2.84Å; R122-L124 PolarHBondContact O-N 3.36Å; L124-L128 WeakPolarHBondContact O-CB 3.31Å; L124-L128 PolarHBondContact O-N 3.47Å; L124-L194 HydrophobicContact CD2-CD1 3.71Å; L124-L194 HydrophobicContact CD2-CG 4.21Å; L124-A198 HydrophobicContact CD1-CB 4.01Å; L124-A198 HydrophobicContact CD2-CB 4.37Å; L124-R203 HydrophobicContact CD1-CB 3.97Å; L124-R203 HydrophobicContact CD1-CG 3.7Å
125R96.3Very high95Very high5 Ų537.7 Ų37.72%0.01918%0.177CC..Hα-helixtrans-62.3-48.8178.9-80.2-167.5-58.7-84.5-2112.8I114 G116 G121 R122 L128 A129 V322I114-R125 HydrophobicContact CB-CG 3.75Å; I114-R125 HydrophobicContact CD1-CG 4.47Å; I114-R125 HydrophobicContact CG2-CG 3.79Å; I114-R125 PolarHBondContact O-NH1 3.37Å; G116-R125 PolarHBondContact O-NH1 2.88Å; G116-R125 PolarHBondContact O-NH2 2.65Å; G121-R125 PolarHBondContact O-N 3.04Å; G121-R125 VanDerWaalsContact O-N 3.15Å; G121-R125 PolarHBondContact O-NH1 3.35Å; R122-R125 PolarHBondContact O-N 2.99Å; R125-L128 PolarHBondContact O-N 3.17Å; R125-A129 PolarHBondContact O-N 3.46Å; R125-V322 HydrophobicContact CB-CB 4.07Å; R125-V322 HydrophobicContact CB-CG2 4.37Å; R125-V322 WeakPolarHBondContact CD-O 3.37Å; R125-V322 PolarHBondContact NE-O 3.42Å
126R95.1Very high95.3Very high67 Ų6735.9 Ų35.925%0.25317%0.169SC..Hα-helixtrans-66.5-40.3179.4-70.3-179.965.377.89.5112.2R122 A129 R130 Y319 V322 D323R122-R126 HydrophobicContact CG-CG 4.33Å; R122-R126 WeakPolarHBondContact O-CB 3.48Å; R122-R126 WeakPolarHBondContact O-CG 3.39Å; R122-R126 PolarHBondContact O-N 3.31Å; R126-A129 PolarHBondContact O-N 3.18Å; R126-R130 VanDerWaalsContact O-CB 3.28Å; R126-R130 WeakPolarHBondContact O-CB 3.32Å; R126-R130 PolarHBondContact O-N 3.17Å; R126-Y319 HydrophobicContact CB-CE1 4.34Å; R126-Y319 HydrophobicContact CG-CD1 4.38Å; R126-V322 HydrophobicContact CG-CG2 4.4Å; R126-D323 WeakPolarHBondContact CD-OD2 3.37Å; R126-D323 IonicContact CZ-OD2 2.59Å; R126-D323 IonicContact NE-OD2 3.72Å; R126-D323 IonicContact NH1-OD2 3.25Å; R126-D323 PolarHBondContact NH1-OD2 3.28Å
127T96.8Very high95.7Very high14 Ų1435.3 Ų35.39%0.08616%0.163CC..Hα-helixtrans-65.5-41.8177.3-57.80000110.8L123 R130 Y131 L194L123-T127 WeakPolarHBondContact O-CB 3.34Å; L123-T127 PolarHBondContact O-N 2.97Å; L123-T127 PolarHBondContact O-OG1 2.84Å; T127-R130 PolarHBondContact O-N 3.29Å; T127-Y131 HydrophobicContact CG2-CD1 4.33Å; T127-Y131 HydrophobicContact CG2-CD2 4.14Å; T127-Y131 HydrophobicContact CG2-CE1 3.8Å; T127-Y131 HydrophobicContact CG2-CE2 3.6Å; T127-Y131 HydrophobicContact CG2-CG 4.49Å; T127-Y131 VanDerWaalsContact CG2-CZ 3.41Å; T127-Y131 PolarHBondContact O-N 2.86Å; T127-L194 HydrophobicContact CG2-CD2 3.74Å
128L97.6Very high96.1Very high0 Ų027.7 Ų27.70%012%0.123CC..Hα-helixtrans-60.5-48.5173.9-178.359.4000111.7M106 A110 I114 L124 R125 R130 Y131 I132 A191 L194 V195 L213 I217M106-L128 HydrophobicContact CE-CD1 3.96Å; M106-L128 HydrophobicContact CE-CD2 3.79Å; M106-L128 HydrophobicContact CE-CG 3.91Å; A110-L128 HydrophobicContact CB-CD2 3.78Å; I114-L128 HydrophobicContact CD1-CD2 3.59Å; L124-L128 WeakPolarHBondContact O-CB 3.31Å; L124-L128 PolarHBondContact O-N 3.47Å; R125-L128 PolarHBondContact O-N 3.17Å; L128-R130 VanDerWaalsContact C-N 3.27Å; L128-R130 PolarHBondContact O-N 3.21Å; L128-Y131 PolarHBondContact O-N 3.37Å; L128-I132 HydrophobicContact CD1-CG1 4.34Å; L128-I132 VanDerWaalsContact O-CG1 3.25Å; L128-I132 WeakPolarHBondContact O-CG1 3.41Å; L128-I132 PolarHBondContact O-N 2.82Å; L128-I132 VanDerWaalsContact O-N 3.13Å; L128-A191 HydrophobicContact CD1-CB 3.62Å; L128-L194 HydrophobicContact CB-CD2 3.99Å; L128-V195 HydrophobicContact CD1-CG2 4.14Å; L128-V195 HydrophobicContact CD2-CG2 4.12Å; L128-L213 HydrophobicContact CD2-CD1 4.18Å; L128-L213 HydrophobicContact CD2-CD2 3.82Å; L128-L213 HydrophobicContact CD2-CG 4.23Å; L128-I217 HydrophobicContact CD1-CD1 4.36Å
129A97.2Very high96.2Very high0 Ų024.4 Ų24.40%011%0.106CC..Hα-helixtrans-56.7-43.1176.300000112M107 R125 R126 I132 N133 Y319 V322M107-A129 HydrophobicContact CE-CB 4.32Å; M107-A129 HydrophobicContact SD-CB 3.48Å; M107-A129 WeakPolarHBondContact SD-CB 3.14Å; R125-A129 PolarHBondContact O-N 3.46Å; R126-A129 PolarHBondContact O-N 3.18Å; A129-I132 PolarHBondContact O-N 3.49Å; A129-N133 PolarHBondContact O-N 3.23Å; A129-N133 PolarHBondContact O-ND2 2.95Å; A129-Y319 HydrophobicContact CB-CE1 4.39Å; A129-V322 HydrophobicContact CB-CG1 4.48Å; A129-V322 HydrophobicContact CB-CG2 4.11Å
130R96.8Very high96.3Very high29 Ų2918.8 Ų18.811%0.1098%0.08CC..Hα-helixtrans-65.2-45.3179.7-169.2162.75477.62.8112.4R126 T127 L128 I132 N133 L134 G161 I162 E167 Y319R126-R130 VanDerWaalsContact O-CB 3.28Å; R126-R130 WeakPolarHBondContact O-CB 3.32Å; R126-R130 PolarHBondContact O-N 3.17Å; T127-R130 PolarHBondContact O-N 3.29Å; L128-R130 VanDerWaalsContact C-N 3.27Å; L128-R130 PolarHBondContact O-N 3.21Å; R130-I132 PolarHBondContact O-N 3.44Å; R130-N133 PolarHBondContact O-N 3.43Å; R130-L134 WeakPolarHBondContact O-CB 3.36Å; R130-L134 PolarHBondContact O-N 3.13Å; R130-G161 WeakPolarHBondContact CD-O 3.26Å; R130-I162 WeakPolarHBondContact CG-O 3.42Å; R130-E167 IonicContact CZ-OE1 3.13Å; R130-E167 IonicContact CZ-OE2 3.04Å; R130-E167 IonicContact NH1-OE1 2.79Å; R130-E167 PolarHBondContact NH1-OE1 3.4Å; R130-E167 IonicContact NH1-OE2 3.76Å; R130-E167 PolarHBondContact NH1-OE2 3Å; R130-E167 IonicContact NH2-OE1 3.64Å; R130-E167 PolarHBondContact NH2-OE1 3.24Å; R130-E167 IonicContact NH2-OE2 3.14Å; R130-Y319 WeakPolarHBondContact CD-OH 3.47Å
131Y98.3Very high96.1Very high34 Ų3416.1 Ų16.113%0.1337%0.069CC..Hα-helixtrans-62-39.7176.5-69.6-10.7000113.4T127 L128 L134 C135 E167 P187 W190 A191 L194T127-Y131 HydrophobicContact CG2-CD1 4.33Å; T127-Y131 HydrophobicContact CG2-CD2 4.14Å; T127-Y131 HydrophobicContact CG2-CE1 3.8Å; T127-Y131 HydrophobicContact CG2-CE2 3.6Å; T127-Y131 HydrophobicContact CG2-CG 4.49Å; T127-Y131 VanDerWaalsContact CG2-CZ 3.41Å; T127-Y131 PolarHBondContact O-N 2.86Å; L128-Y131 PolarHBondContact O-N 3.37Å; Y131-L134 PolarHBondContact O-N 2.85Å; Y131-C135 PolarHBondContact O-N 2.91Å; Y131-E167 HydrophobicContact CE1-CG 4.44Å; Y131-E167 WeakPolarHBondContact CE1-OE1 3.32Å; Y131-P187 WeakPolarHBondContact O-CB 3.13Å; Y131-W190 HydrophobicContact CD1-CE3 4.38Å; Y131-W190 HydrophobicContact CD2-CB 3.72Å; Y131-W190 HydrophobicContact CE1-CE3 4.23Å; Y131-W190 HydrophobicContact CE2-CB 3.6Å; Y131-W190 HydrophobicContact CG-CB 4.4Å; Y131-A191 HydrophobicContact CD2-CB 4.4Å; Y131-L194 HydrophobicContact CD2-CD2 4.32Å; Y131-L194 HydrophobicContact CE2-CD2 4.24Å
132I98Very high96Very high0 Ų018.9 Ų18.90%08%0.084CC..Hα-helixtrans-65.7-47.8176.4-61.9-68.3000110.6I103 M106 M107 L128 A129 R130 L134 C135 C136 L188 A191 I217 V220I103-I132 HydrophobicContact CB-CG2 4.45Å; I103-I132 HydrophobicContact CG2-CG2 3.91Å; M106-I132 HydrophobicContact CE-CD1 3.99Å; M106-I132 HydrophobicContact CE-CG1 3.98Å; M106-I132 HydrophobicContact CG-CG1 4.37Å; M106-I132 HydrophobicContact CG-CG2 4.44Å; M107-I132 HydrophobicContact CE-CB 3.85Å; M107-I132 HydrophobicContact CE-CG1 4.08Å; M107-I132 HydrophobicContact CE-CG2 3.85Å; L128-I132 HydrophobicContact CD1-CG1 4.34Å; L128-I132 VanDerWaalsContact O-CG1 3.25Å; L128-I132 WeakPolarHBondContact O-CG1 3.41Å; L128-I132 PolarHBondContact O-N 2.82Å; L128-I132 VanDerWaalsContact O-N 3.13Å; A129-I132 PolarHBondContact O-N 3.49Å; R130-I132 PolarHBondContact O-N 3.44Å; I132-L134 VanDerWaalsContact C-N 3.33Å; I132-L134 PolarHBondContact O-N 2.78Å; I132-C135 PolarHBondContact O-N 3.34Å; I132-C136 PolarHBondContact O-N 3.28Å; I132-C136 PolarHBondContact O-SG 3.27Å; I132-C136 VanDerWaalsContact O-SG 3.35Å; I132-L188 HydrophobicContact CD1-CD2 3.64Å; I132-A191 HydrophobicContact CD1-CB 4.09Å; I132-I217 HydrophobicContact CD1-CB 4.4Å; I132-I217 HydrophobicContact CD1-CG1 3.93Å; I132-I217 HydrophobicContact CD1-CG2 4.08Å; I132-V220 HydrophobicContact CG2-CG1 4.27Å; I132-V220 HydrophobicContact CG2-CG2 4.18Å
133N97.4Very high95.7Very high4 Ų416.2 Ų16.22%0.0218%0.076CC..Hα-helixtrans-61.7-41.4175.1-80.3-66.8000111.8I103 A129 R130 C135 C136 V137 N314 V315 S318I103-N133 WeakPolarHBondContact CD1-ND2 3.08Å; I103-N133 WeakPolarHBondContact CD1-OD1 3.48Å; A129-N133 PolarHBondContact O-N 3.23Å; A129-N133 PolarHBondContact O-ND2 2.95Å; R130-N133 PolarHBondContact O-N 3.43Å; N133-C135 PolarHBondContact O-N 3.23Å; N133-C136 WeakPolarHBondContact O-CB 3.34Å; N133-C136 PolarHBondContact O-N 2.82Å; N133-C136 VanDerWaalsContact O-N 3.15Å; N133-V137 WeakPolarHBondContact O-CB 3.31Å; N133-V137 VanDerWaalsContact O-CG2 3.29Å; N133-V137 WeakPolarHBondContact O-CG2 3.46Å; N133-V137 PolarHBondContact O-N 3.43Å; N133-N314 WeakPolarHBondContact OD1-CB 3.43Å; N133-V315 HydrophobicContact CB-CG2 4.11Å; N133-V315 PolarHBondContact OD1-N 3.1Å; N133-S318 PolarHBondContact ND2-OG 3.34Å
134L97.3Very high95.4Very high0 Ų012.5 Ų12.50%06%0.057CC..Hα-helixtrans-59.7-46.3179.6176.361.5000111.6R130 Y131 I132 C136 V137 I138 L157 I162 M163 P187 W190R130-L134 WeakPolarHBondContact O-CB 3.36Å; R130-L134 PolarHBondContact O-N 3.13Å; Y131-L134 PolarHBondContact O-N 2.85Å; I132-L134 VanDerWaalsContact C-N 3.33Å; I132-L134 PolarHBondContact O-N 2.78Å; L134-C136 VanDerWaalsContact C-N 3.33Å; L134-C136 PolarHBondContact O-N 3.46Å; L134-V137 PolarHBondContact O-N 3.05Å; L134-I138 HydrophobicContact CD1-CD1 3.98Å; L134-I138 HydrophobicContact CD1-CG1 4.14Å; L134-I138 HydrophobicContact CG-CD1 3.98Å; L134-I138 VanDerWaalsContact O-CG1 3.28Å; L134-I138 WeakPolarHBondContact O-CG1 3.13Å; L134-I138 PolarHBondContact O-N 3.49Å; L134-L157 HydrophobicContact CD1-CD1 4.29Å; L134-I162 HydrophobicContact CB-CG2 4.19Å; L134-I162 HydrophobicContact CD1-CG2 3.97Å; L134-M163 HydrophobicContact CD1-CB 4.25Å; L134-M163 HydrophobicContact CD1-CG 4.22Å; L134-M163 HydrophobicContact CD1-SD 3.71Å; L134-M163 HydrophobicContact CD2-CB 4.5Å; L134-M163 HydrophobicContact CD2-CE 3.79Å; L134-M163 HydrophobicContact CD2-CG 3.83Å; L134-M163 HydrophobicContact CD2-SD 3.78Å; L134-M163 HydrophobicContact CG-SD 4.37Å; L134-P187 HydrophobicContact CB-CB 4.39Å; L134-P187 HydrophobicContact CD2-CB 4.08Å; L134-P187 HydrophobicContact CD2-CG 3.87Å; L134-P187 HydrophobicContact CG-CB 4.21Å; L134-P187 HydrophobicContact CG-CG 3.92Å; L134-W190 HydrophobicContact CD2-CZ3 4.32Å
135C97.5Very high94.8Very high0 Ų015 Ų150%08%0.078CC..Hα-helixtrans-56.9-47.3173.3175.50000111.8Y131 I132 N133 V137 I138 V139 Y184 P187 L188Y131-C135 PolarHBondContact O-N 2.91Å; I132-C135 PolarHBondContact O-N 3.34Å; N133-C135 PolarHBondContact O-N 3.23Å; C135-V137 VanDerWaalsContact C-N 3.33Å; C135-V137 PolarHBondContact O-N 3.03Å; C135-I138 PolarHBondContact O-N 3.39Å; C135-V139 WeakPolarHBondContact O-CG2 3.32Å; C135-V139 PolarHBondContact O-N 3.32Å; C135-V139 VanDerWaalsContact O-N 3.12Å; C135-Y184 PolarHBondContact SG-O 2.82Å; C135-Y184 VanDerWaalsContact SG-O 3.41Å; C135-P187 HydrophobicContact CB-CB 4.22Å; C135-L188 HydrophobicContact CB-CD1 4.4Å; C135-L188 HydrophobicContact CB-CD2 3.66Å; C135-L188 HydrophobicContact CB-CG 3.7Å; C135-L188 VanDerWaalsContact SG-CG 3.51Å
136C97.6Very high94.3Very high3 Ų316.6 Ų16.62%0.029%0.088CC..Hα-helixtrans-60.3-44.5178.3-66.10000111.1P101 I132 N133 L134 V139 L140P101-C136 VanDerWaalsContact CB-SG 3.58Å; P101-C136 HydrophobicContact CG-CB 3.99Å; I132-C136 PolarHBondContact O-N 3.28Å; I132-C136 PolarHBondContact O-SG 3.27Å; I132-C136 VanDerWaalsContact O-SG 3.35Å; N133-C136 WeakPolarHBondContact O-CB 3.34Å; N133-C136 PolarHBondContact O-N 2.82Å; N133-C136 VanDerWaalsContact O-N 3.15Å; L134-C136 VanDerWaalsContact C-N 3.33Å; L134-C136 PolarHBondContact O-N 3.46Å; C136-V139 PolarHBondContact O-N 2.75Å; C136-L140 VanDerWaalsContact O-CB 3.27Å; C136-L140 WeakPolarHBondContact O-CB 3.49Å; C136-L140 WeakPolarHBondContact O-CG 3.48Å; C136-L140 PolarHBondContact O-N 2.67Å
137V96.4Very high94Very high2 Ų213.4 Ų13.41%0.0128%0.076CC..Hα-helixtrans-67.1-39.2-179.2171.70000111.7N133 L134 C135 L140 R141 F151 L157 I162 V311N133-V137 WeakPolarHBondContact O-CB 3.31Å; N133-V137 VanDerWaalsContact O-CG2 3.29Å; N133-V137 WeakPolarHBondContact O-CG2 3.46Å; N133-V137 PolarHBondContact O-N 3.43Å; L134-V137 PolarHBondContact O-N 3.05Å; C135-V137 VanDerWaalsContact C-N 3.33Å; C135-V137 PolarHBondContact O-N 3.03Å; V137-L140 PolarHBondContact O-N 3.5Å; V137-R141 WeakPolarHBondContact O-CB 3.38Å; V137-R141 PolarHBondContact O-N 2.8Å; V137-F151 HydrophobicContact CG1-CD2 3.99Å; V137-F151 HydrophobicContact CG1-CE2 4.07Å; V137-L157 HydrophobicContact CG1-CD2 3.57Å; V137-I162 HydrophobicContact CG2-CD1 4.36Å; V137-V311 HydrophobicContact CG2-CG1 3.75Å; V137-V311 HydrophobicContact CG2-CG2 4.19Å
138I95.5Very high93.5Very high0 Ų016.6 Ų16.60%09%0.089CC..Hα-helixtrans-59.2-51.2174.5-71168.6000110.2L134 C135 R141 D142 W154 Y171 P187L134-I138 HydrophobicContact CD1-CD1 3.98Å; L134-I138 HydrophobicContact CD1-CG1 4.14Å; L134-I138 HydrophobicContact CG-CD1 3.98Å; L134-I138 VanDerWaalsContact O-CG1 3.28Å; L134-I138 WeakPolarHBondContact O-CG1 3.13Å; L134-I138 PolarHBondContact O-N 3.49Å; C135-I138 PolarHBondContact O-N 3.39Å; I138-R141 PolarHBondContact O-N 2.86Å; I138-D142 PolarHBondContact O-N 2.91Å; I138-D142 VanDerWaalsContact O-N 3.15Å; I138-W154 HydrophobicContact CD1-CH2 4.48Å; I138-W154 HydrophobicContact CD1-CZ3 4.14Å; I138-W154 HydrophobicContact CG1-CH2 4.21Å; I138-W154 HydrophobicContact CG1-CZ3 3.89Å; I138-W154 HydrophobicContact CG2-CH2 4.44Å; I138-Y171 HydrophobicContact CD1-CD2 4.47Å; I138-Y171 HydrophobicContact CD1-CE2 3.8Å; I138-P187 HydrophobicContact CD1-CG 3.9Å
139V95.8Very high93Very high0 Ų023.4 Ų23.40%012%0.119CC..Hα-helixtrans-63.6-46.9179.8175.10000111.1C135 C136 R141 D142 V143 Y184 V224 I228C135-V139 WeakPolarHBondContact O-CG2 3.32Å; C135-V139 PolarHBondContact O-N 3.32Å; C135-V139 VanDerWaalsContact O-N 3.12Å; C136-V139 PolarHBondContact O-N 2.75Å; V139-R141 VanDerWaalsContact C-N 3.32Å; V139-R141 PolarHBondContact O-N 3.49Å; V139-D142 PolarHBondContact O-N 2.79Å; V139-D142 VanDerWaalsContact O-N 3.14Å; V139-V143 HydrophobicContact CG1-CG1 4.41Å; V139-V143 WeakPolarHBondContact O-CG2 2.74Å; V139-V143 PolarHBondContact O-N 3.43Å; V139-Y184 HydrophobicContact CG2-CD2 3.55Å; V139-Y184 HydrophobicContact CG2-CE2 4.47Å; V139-Y184 HydrophobicContact CG2-CG 3.9Å; V139-V224 HydrophobicContact CB-CB 4.35Å; V139-V224 HydrophobicContact CG1-CB 4.21Å; V139-V224 HydrophobicContact CG2-CB 4.11Å; V139-V224 HydrophobicContact CG2-CG2 4.47Å; V139-I228 HydrophobicContact CG1-CD1 4.15Å; V139-I228 HydrophobicContact CG1-CG1 3.7Å; V139-I228 HydrophobicContact CG2-CD1 3.88Å; V139-I228 HydrophobicContact CG2-CG1 4.35Å
140L94.7Very high92.6Very high2 Ų227.2 Ų27.21%0.0113%0.133CC..Hα-helixtrans-63.3-37.2179.1-70.6173.5000112.3L100 C136 V137 D142 V143 S144 V147 L227 I307 V311L100-L140 HydrophobicContact CD2-CD2 4.32Å; C136-L140 VanDerWaalsContact O-CB 3.27Å; C136-L140 WeakPolarHBondContact O-CB 3.49Å; C136-L140 WeakPolarHBondContact O-CG 3.48Å; C136-L140 PolarHBondContact O-N 2.67Å; V137-L140 PolarHBondContact O-N 3.5Å; L140-D142 VanDerWaalsContact C-N 3.27Å; L140-D142 PolarHBondContact O-N 3.44Å; L140-V143 HydrophobicContact CD2-CG2 4.46Å; L140-V143 PolarHBondContact O-N 3.01Å; L140-S144 WeakPolarHBondContact O-CA 3.37Å; L140-S144 VanDerWaalsContact O-CB 3.23Å; L140-S144 WeakPolarHBondContact O-CB 3.44Å; L140-S144 PolarHBondContact O-N 2.78Å; L140-V147 HydrophobicContact CB-CG1 4.42Å; L140-V147 HydrophobicContact CB-CG2 4.38Å; L140-L227 HydrophobicContact CD2-CD1 4.29Å; L140-I307 HydrophobicContact CB-CG2 4.04Å; L140-I307 HydrophobicContact CD1-CG2 3.82Å; L140-I307 HydrophobicContact CD2-CG2 3.76Å; L140-I307 HydrophobicContact CG-CG2 4.07Å; L140-V311 HydrophobicContact CD1-CG2 3.84Å
141R91.5Very high92.3Very high19 Ų1926 Ų267%0.07213%0.128CC..Hα-helixtrans-61-36.6174.2175.8-174.4170.9-99.18.4111.9V137 I138 V139 V147 K148 F151 P152V137-R141 WeakPolarHBondContact O-CB 3.38Å; V137-R141 PolarHBondContact O-N 2.8Å; I138-R141 PolarHBondContact O-N 2.86Å; V139-R141 VanDerWaalsContact C-N 3.32Å; V139-R141 PolarHBondContact O-N 3.49Å; R141-V147 HydrophobicContact CB-CG1 3.94Å; R141-K148 HydrophobicContact CG-CD 3.68Å; R141-K148 VanDerWaalsContact CZ-NZ 3.29Å; R141-K148 VanDerWaalsContact NH1-NZ 3.15Å; R141-K148 WeakPolarHBondContact O-CB 3.42Å; R141-K148 WeakPolarHBondContact O-CD 3.37Å; R141-F151 VanDerWaalsContact CD-O 3.26Å; R141-F151 WeakPolarHBondContact CD-O 3.46Å; R141-F151 PolarHBondContact NE-O 2.64Å; R141-P152 PolarHBondContact NH2-O 3.46Å
142D89.6Confident91.8Very high59 Ų5927 Ų2732%0.31614%0.139SC..Hα-helixtrans-89.9-18.1-176.2-67.8-21.8000113.4I138 V139 L140 K148 Y182I138-D142 PolarHBondContact O-N 2.91Å; I138-D142 VanDerWaalsContact O-N 3.15Å; V139-D142 PolarHBondContact O-N 2.79Å; V139-D142 VanDerWaalsContact O-N 3.14Å; L140-D142 VanDerWaalsContact C-N 3.27Å; L140-D142 PolarHBondContact O-N 3.44Å; D142-K148 IonicContact OD1-NZ 2.82Å; D142-K148 PolarHBondContact OD1-NZ 3.19Å; D142-Y182 PolarHBondContact OD2-OH 2.9Å
143V89.3Confident91.4Very high20 Ų2030 Ų3012%0.12116%0.158CC..Hα-helixtrans-102.3-17.7174.6-530000114.8V139 L140 N231V139-V143 HydrophobicContact CG1-CG1 4.41Å; V139-V143 WeakPolarHBondContact O-CG2 2.74Å; V139-V143 PolarHBondContact O-N 3.43Å; L140-V143 HydrophobicContact CD2-CG2 4.46Å; L140-V143 PolarHBondContact O-N 3.01Å; V143-N231 HydrophobicContact CB-CB 4.33Å; V143-N231 HydrophobicContact CG1-CB 3.78Å
144S88.3Confident91.1Very high3 Ų332.3 Ų32.32%0.02117%0.166CC..  trans-118.9122.8-179.2178.40000112L140 V146 V147 K148 F298L140-S144 WeakPolarHBondContact O-CA 3.37Å; L140-S144 VanDerWaalsContact O-CB 3.23Å; L140-S144 WeakPolarHBondContact O-CB 3.44Å; L140-S144 PolarHBondContact O-N 2.78Å; S144-V146 VanDerWaalsContact C-N 3.28Å; S144-V146 PolarHBondContact O-N 2.98Å; S144-V147 PolarHBondContact O-N 2.88Å; S144-K148 PolarHBondContact O-N 3.44Å; S144-F298 PolarHBondContact OG-O 3.44Å
145A83.4Confident90.8Very high54 Ų5435.9 Ų35.945%0.44619%0.185SC..Hα-helixtrans-61-38.1177.400000112.1V147 K148 K149A145-V147 VanDerWaalsContact C-N 3.35Å; A145-V147 PolarHBondContact O-N 2.82Å; A145-K148 WeakPolarHBondContact O-CB 3.22Å; A145-K148 PolarHBondContact O-N 3.38Å; A145-K149 WeakPolarHBondContact O-CG 3.42Å; A145-K149 PolarHBondContact O-N 3.26Å
146V86.3Confident90.5Very high38 Ų3839 Ų3923%0.2320%0.2CC..Hα-helixtrans-63-40.8179.2175.10000111.9S144 R150 G299 E300 N308S144-V146 VanDerWaalsContact C-N 3.28Å; S144-V146 PolarHBondContact O-N 2.98Å; V146-R150 PolarHBondContact O-N 2.89Å; V146-G299 WeakPolarHBondContact CG2-O 3.31Å; V146-E300 HydrophobicContact CG2-CG 3.35Å; V146-N308 WeakPolarHBondContact CG1-ND2 3.42Å
147V87.9Confident90.2Very high0 Ų038.9 Ų38.90%020%0.199CC..Hα-helixtrans-73.3-35.9176-175.50000110.7L140 R141 S144 A145 K149 R150 F151 I307L140-V147 HydrophobicContact CB-CG1 4.42Å; L140-V147 HydrophobicContact CB-CG2 4.38Å; R141-V147 HydrophobicContact CB-CG1 3.94Å; S144-V147 PolarHBondContact O-N 2.88Å; A145-V147 VanDerWaalsContact C-N 3.35Å; A145-V147 PolarHBondContact O-N 2.82Å; V147-K149 VanDerWaalsContact C-N 3.34Å; V147-K149 PolarHBondContact O-N 3.14Å; V147-R150 PolarHBondContact O-N 3.45Å; V147-F151 HydrophobicContact CG1-CD2 3.7Å; V147-F151 HydrophobicContact CG1-CE2 4.14Å; V147-F151 PolarHBondContact O-N 3.16Å; V147-I307 HydrophobicContact CG2-CB 3.81Å; V147-I307 HydrophobicContact CG2-CG2 3.33Å
148K87.8Confident90Very high82 Ų8240.2 Ų40.236%0.35721%0.207SC..Hα-helixtrans-61.3-41173.2-164.568.7165.8-153.20112.3R141 D142 S144 A145 R150 F151 P152R141-K148 HydrophobicContact CG-CD 3.68Å; R141-K148 VanDerWaalsContact CZ-NZ 3.29Å; R141-K148 VanDerWaalsContact NH1-NZ 3.15Å; R141-K148 WeakPolarHBondContact O-CB 3.42Å; R141-K148 WeakPolarHBondContact O-CD 3.37Å; D142-K148 IonicContact OD1-NZ 2.82Å; D142-K148 PolarHBondContact OD1-NZ 3.19Å; S144-K148 PolarHBondContact O-N 3.44Å; A145-K148 WeakPolarHBondContact O-CB 3.22Å; A145-K148 PolarHBondContact O-N 3.38Å; K148-R150 VanDerWaalsContact C-N 3.31Å; K148-R150 PolarHBondContact O-N 3.15Å; K148-F151 CarbonylContact O-C 3.58Å; K148-F151 VanDerWaalsContact O-C 3.26Å; K148-F151 PolarHBondContact O-N 3.4Å; K148-P152 WeakPolarHBondContact O-CA 3.23Å
149K87.3Confident89.7Confident143 Ų14347.7 Ų47.762%0.62224%0.239SC*.Hα-helixtrans-63.5-36.9174.6-74.9180179.8-179.70111.9A145 V147 E300A145-K149 WeakPolarHBondContact O-CG 3.42Å; A145-K149 PolarHBondContact O-N 3.26Å; V147-K149 VanDerWaalsContact C-N 3.34Å; V147-K149 PolarHBondContact O-N 3.14Å; K149-E300 WeakPolarHBondContact CD-OE1 3.1Å; K149-E300 WeakPolarHBondContact CE-OE1 2.99Å; K149-E300 IonicContact NZ-OE1 2.82Å; K149-E300 PolarHBondContact NZ-OE1 3.4Å; K149-E300 IonicContact NZ-OE2 2.97Å; K149-E300 PolarHBondContact NZ-OE2 2.96Å
150R88.5Confident89.4Confident80 Ų8051.1 Ų51.130%0.30226%0.26SS..Hα-helixtrans-72.7-40.9177-175.9179.1174.9177.20.7113V146 V147 K148 P152 N308 D312V146-R150 PolarHBondContact O-N 2.89Å; V147-R150 PolarHBondContact O-N 3.45Å; K148-R150 VanDerWaalsContact C-N 3.31Å; K148-R150 PolarHBondContact O-N 3.15Å; R150-P152 VanDerWaalsContact C-CD 3.42Å; R150-P152 WeakPolarHBondContact O-CD 3.38Å; R150-N308 WeakPolarHBondContact CD-OD1 3.19Å; R150-N308 PolarHBondContact NH1-O 2.99Å; R150-D312 IonicContact CZ-OD1 3.3Å; R150-D312 VanDerWaalsContact CZ-OD1 3.29Å; R150-D312 IonicContact CZ-OD2 3.88Å; R150-D312 IonicContact NH1-OD1 2.78Å; R150-D312 PolarHBondContact NH1-OD1 3.25Å; R150-D312 IonicContact NH1-OD2 3.17Å; R150-D312 PolarHBondContact NH1-OD2 3.13Å; R150-D312 IonicContact NH2-OD1 2.69Å; R150-D312 PolarHBondContact NH2-OD1 2.8Å; R150-D312 IonicContact NH2-OD2 2.72Å
151F90.8Very high89.1Confident2 Ų253 Ų531%0.00928%0.28CS..SBendtrans-122.966.9-178.1-52.6-59.9000110.8V137 R141 V147 K148 T153 H156 L157 T160 I162 V311V137-F151 HydrophobicContact CG1-CD2 3.99Å; V137-F151 HydrophobicContact CG1-CE2 4.07Å; R141-F151 VanDerWaalsContact CD-O 3.26Å; R141-F151 WeakPolarHBondContact CD-O 3.46Å; R141-F151 PolarHBondContact NE-O 2.64Å; V147-F151 HydrophobicContact CG1-CD2 3.7Å; V147-F151 HydrophobicContact CG1-CE2 4.14Å; V147-F151 PolarHBondContact O-N 3.16Å; K148-F151 CarbonylContact O-C 3.58Å; K148-F151 VanDerWaalsContact O-C 3.26Å; K148-F151 PolarHBondContact O-N 3.4Å; F151-T153 VanDerWaalsContact C-N 3.31Å; F151-T153 PolarHBondContact O-N 2.88Å; F151-H156 HydrophobicContact CD1-CB 4.25Å; F151-L157 HydrophobicContact CB-CD2 3.84Å; F151-L157 HydrophobicContact CB-CG 4.43Å; F151-L157 HydrophobicContact CD1-CD2 3.76Å; F151-L157 HydrophobicContact CD2-CD2 4.03Å; F151-L157 HydrophobicContact CE1-CD2 4.28Å; F151-L157 HydrophobicContact CG-CD2 3.61Å; F151-T160 HydrophobicContact CE1-CG2 3.8Å; F151-I162 HydrophobicContact CE1-CD1 4.38Å; F151-I162 HydrophobicContact CZ-CD1 4.04Å; F151-V311 HydrophobicContact CE2-CG1 4.19Å; F151-V311 HydrophobicContact CZ-CG1 4.44Å
152P86.6Confident89.1Confident55 Ų5552.5 Ų52.536%0.35728%0.279SS..  trans-67.8-33.3-173.625.8-33.9000112.1R141 K148 R150R141-P152 PolarHBondContact NH2-O 3.46Å; K148-P152 WeakPolarHBondContact O-CA 3.23Å; R150-P152 VanDerWaalsContact C-CD 3.42Å; R150-P152 WeakPolarHBondContact O-CD 3.38Å
153T91Very high89.3Confident64 Ų6449.9 Ų49.939%0.39326%0.264SS..SBendtrans-125.2162.6-179.973.80000111.7F151 D155 H156F151-T153 VanDerWaalsContact C-N 3.31Å; F151-T153 PolarHBondContact O-N 2.88Å; T153-D155 VanDerWaalsContact C-N 3.25Å; T153-D155 PolarHBondContact O-N 3.27Å; T153-H156 WeakPolarHBondContact O-CB 3.38Å; T153-H156 PolarHBondContact O-N 3.26Å; T153-H156 VanDerWaalsContact O-N 3.14Å; T153-H156 PolarHBondContact OG1-CE1 2.97Å; T153-H156 PolarHBondContact OG1-ND1 3.47Å
154W90.7Very high89.6Confident53 Ų5351.2 Ų51.220%0.20127%0.273CS..Hα-helixtrans-62.3-32176.8-58.4103.8000112.9I138 H156 L157 V158 V168 Y171 L172I138-W154 HydrophobicContact CD1-CH2 4.48Å; I138-W154 HydrophobicContact CD1-CZ3 4.14Å; I138-W154 HydrophobicContact CG1-CH2 4.21Å; I138-W154 HydrophobicContact CG1-CZ3 3.89Å; I138-W154 HydrophobicContact CG2-CH2 4.44Å; W154-H156 PolarHBondContact O-N 3.05Å; W154-L157 HydrophobicContact CE3-CD1 3.79Å; W154-L157 HydrophobicContact CZ3-CD1 3.95Å; W154-L157 WeakPolarHBondContact O-CA 3.27Å; W154-L157 WeakPolarHBondContact O-CB 3.18Å; W154-L157 PolarHBondContact O-N 3.1Å; W154-V158 PolarHBondContact O-N 3.27Å; W154-V158 VanDerWaalsContact O-N 3.17Å; W154-V168 HydrophobicContact CB-CG1 3.96Å; W154-Y171 HydrophobicContact CE3-CD1 4.42Å; W154-Y171 HydrophobicContact CE3-CE1 4.45Å; W154-Y171 HydrophobicContact CH2-CD1 4.01Å; W154-Y171 AromaticContact CH2-CE1 3.26Å; W154-Y171 HydrophobicContact CH2-CE1 3.26Å; W154-Y171 AromaticContact CH2-CZ 3.93Å; W154-Y171 HydrophobicContact CZ2-CD1 4.35Å; W154-Y171 AromaticContact CZ2-CE1 3.7Å; W154-Y171 HydrophobicContact CZ2-CE1 3.7Å; W154-Y171 HydrophobicContact CZ3-CD1 4.03Å; W154-Y171 AromaticContact CZ3-CE1 3.68Å; W154-Y171 HydrophobicContact CZ3-CE1 3.68Å; W154-L172 HydrophobicContact CD2-CD2 4.2Å; W154-L172 HydrophobicContact CG-CD1 4.43Å; W154-L172 HydrophobicContact CG-CD2 4.06Å
155D90.2Very high89.8Confident75 Ų7557.7 Ų57.740%0.40130%0.303SS..Hα-helixtrans-57.5-33.9173.5174.670000112.6T153 L157 V158 K159T153-D155 VanDerWaalsContact C-N 3.25Å; T153-D155 PolarHBondContact O-N 3.27Å; D155-L157 VanDerWaalsContact C-N 3.3Å; D155-L157 PolarHBondContact O-N 3.48Å; D155-V158 WeakPolarHBondContact O-CB 3.49Å; D155-V158 PolarHBondContact O-N 3.31Å; D155-K159 WeakPolarHBondContact O-CG 2.92Å; D155-K159 PolarHBondContact O-N 2.99Å; D155-K159 IonicContact OD1-NZ 2.64Å; D155-K159 WeakPolarHBondContact OD2-CD 2.95Å; D155-K159 WeakPolarHBondContact OD2-CE 3.39Å; D155-K159 IonicContact OD2-NZ 2.92Å; D155-K159 PolarHBondContact OD2-NZ 3.47Å
156H92.3Very high90.4Very high66 Ų6658.9 Ų58.931%0.30631%0.308SS..Hα-helixtrans-66.5-32.6174.7-66.876.6000112.1F151 T153 W154 V158 T160F151-H156 HydrophobicContact CD1-CB 4.25Å; T153-H156 WeakPolarHBondContact O-CB 3.38Å; T153-H156 PolarHBondContact O-N 3.26Å; T153-H156 VanDerWaalsContact O-N 3.14Å; T153-H156 PolarHBondContact OG1-CE1 2.97Å; T153-H156 PolarHBondContact OG1-ND1 3.47Å; W154-H156 PolarHBondContact O-N 3.05Å; H156-V158 VanDerWaalsContact C-N 3.34Å; H156-T160 WeakPolarHBondContact O-CG2 3.42Å; H156-T160 PolarHBondContact O-N 3.31Å; H156-T160 VanDerWaalsContact O-N 3.14Å; H156-T160 PolarHBondContact O-OG1 2.81Å
157L91.3Very high90.8Very high0 Ų057.6 Ų57.60%030%0.299CS..Hα-helixtrans-71.4-32.2174.6-61.6-179.2000111.6L134 V137 F151 W154 D155 T160 G161 I162 M163L134-L157 HydrophobicContact CD1-CD1 4.29Å; V137-L157 HydrophobicContact CG1-CD2 3.57Å; F151-L157 HydrophobicContact CB-CD2 3.84Å; F151-L157 HydrophobicContact CB-CG 4.43Å; F151-L157 HydrophobicContact CD1-CD2 3.76Å; F151-L157 HydrophobicContact CD2-CD2 4.03Å; F151-L157 HydrophobicContact CE1-CD2 4.28Å; F151-L157 HydrophobicContact CG-CD2 3.61Å; W154-L157 HydrophobicContact CE3-CD1 3.79Å; W154-L157 HydrophobicContact CZ3-CD1 3.95Å; W154-L157 WeakPolarHBondContact O-CA 3.27Å; W154-L157 WeakPolarHBondContact O-CB 3.18Å; W154-L157 PolarHBondContact O-N 3.1Å; D155-L157 VanDerWaalsContact C-N 3.3Å; D155-L157 PolarHBondContact O-N 3.48Å; L157-T160 WeakPolarHBondContact CA-OG1 3.5Å; L157-T160 PolarHBondContact O-OG1 2.94Å; L157-T160 VanDerWaalsContact O-OG1 3.11Å; L157-G161 PolarHBondContact O-N 3.36Å; L157-I162 HydrophobicContact CD2-CD1 4.31Å; L157-I162 PolarHBondContact O-N 3.36Å; L157-M163 HydrophobicContact CB-CB 4.32Å; L157-M163 PolarHBondContact O-N 3.39Å
158V92.5Very high91.2Very high30 Ų3058.4 Ų58.418%0.18230%0.304CS..Hα-helixtrans-67.6-51.5172.6-177.40000110.9W154 D155 H156 T160 G161 M163 E165 V168W154-V158 PolarHBondContact O-N 3.27Å; W154-V158 VanDerWaalsContact O-N 3.17Å; D155-V158 WeakPolarHBondContact O-CB 3.49Å; D155-V158 PolarHBondContact O-N 3.31Å; H156-V158 VanDerWaalsContact C-N 3.34Å; V158-T160 PolarHBondContact O-N 2.82Å; V158-G161 WeakPolarHBondContact O-CA 3.25Å; V158-G161 PolarHBondContact O-N 3.16Å; V158-M163 WeakPolarHBondContact CA-O 3.46Å; V158-E165 HydrophobicContact CG1-CG 3.75Å; V158-V168 HydrophobicContact CG2-CB 4.18Å; V158-V168 HydrophobicContact CG2-CG2 3.35Å
159K88.8Confident91.6Very high156 Ų15660.7 Ų60.768%0.67832%0.318SS*.Hα-helixtrans-59.3-31.2-179.7-75.5173.7175.21620113.6D155 G161D155-K159 WeakPolarHBondContact O-CG 2.92Å; D155-K159 PolarHBondContact O-N 2.99Å; D155-K159 IonicContact OD1-NZ 2.64Å; D155-K159 WeakPolarHBondContact OD2-CD 2.95Å; D155-K159 WeakPolarHBondContact OD2-CE 3.39Å; D155-K159 IonicContact OD2-NZ 2.92Å; D155-K159 PolarHBondContact OD2-NZ 3.47Å; K159-G161 VanDerWaalsContact C-N 3.31Å
160T88.5Confident92Very high73 Ų7358.4 Ų58.445%0.44831%0.309SS..THydrogen-bonded Turntrans-83.2-5.517553.70000113.9F151 H156 L157 V158 I162F151-T160 HydrophobicContact CE1-CG2 3.8Å; H156-T160 WeakPolarHBondContact O-CG2 3.42Å; H156-T160 PolarHBondContact O-N 3.31Å; H156-T160 VanDerWaalsContact O-N 3.14Å; H156-T160 PolarHBondContact O-OG1 2.81Å; L157-T160 WeakPolarHBondContact CA-OG1 3.5Å; L157-T160 PolarHBondContact O-OG1 2.94Å; L157-T160 VanDerWaalsContact O-OG1 3.11Å; V158-T160 PolarHBondContact O-N 2.82Å; T160-I162 VanDerWaalsContact C-N 3.25Å; T160-I162 PolarHBondContact O-N 2.81Å
161G89.6Confident92.3Very high40 Ų4054.9 Ų54.941%0.41230%0.296SS..THydrogen-bonded Turntrans73.812.5-179.600000114.5R130 L157 V158 K159 M163R130-G161 WeakPolarHBondContact CD-O 3.26Å; L157-G161 PolarHBondContact O-N 3.36Å; V158-G161 WeakPolarHBondContact O-CA 3.25Å; V158-G161 PolarHBondContact O-N 3.16Å; K159-G161 VanDerWaalsContact C-N 3.31Å; G161-M163 VanDerWaalsContact C-N 3.27Å
162I90.9Very high92.6Very high10 Ų1057.3 Ų57.35%0.05131%0.309CS..SBendtrans-73.8-27.2174.6-61.3173.6000110R130 L134 V137 F151 L157 T160R130-I162 WeakPolarHBondContact CG-O 3.42Å; L134-I162 HydrophobicContact CB-CG2 4.19Å; L134-I162 HydrophobicContact CD1-CG2 3.97Å; V137-I162 HydrophobicContact CG2-CD1 4.36Å; F151-I162 HydrophobicContact CE1-CD1 4.38Å; F151-I162 HydrophobicContact CZ-CD1 4.04Å; L157-I162 HydrophobicContact CD2-CD1 4.31Å; L157-I162 PolarHBondContact O-N 3.36Å; T160-I162 VanDerWaalsContact C-N 3.25Å; T160-I162 PolarHBondContact O-N 2.81Å
163M93.5Very high93Very high3 Ų360.8 Ų60.82%0.01532%0.322CS..SBendtrans-134.5149.2176.6-151.3161-17500109.9L134 L157 V158 G161 E167 V168 Y171 W190L134-M163 HydrophobicContact CD1-CB 4.25Å; L134-M163 HydrophobicContact CD1-CG 4.22Å; L134-M163 HydrophobicContact CD1-SD 3.71Å; L134-M163 HydrophobicContact CD2-CB 4.5Å; L134-M163 HydrophobicContact CD2-CE 3.79Å; L134-M163 HydrophobicContact CD2-CG 3.83Å; L134-M163 HydrophobicContact CD2-SD 3.78Å; L134-M163 HydrophobicContact CG-SD 4.37Å; L157-M163 HydrophobicContact CB-CB 4.32Å; L157-M163 PolarHBondContact O-N 3.39Å; V158-M163 WeakPolarHBondContact CA-O 3.46Å; G161-M163 VanDerWaalsContact C-N 3.27Å; M163-E167 VanDerWaalsContact CE-C 3.41Å; M163-E167 HydrophobicContact CE-CB 3.99Å; M163-E167 WeakPolarHBondContact CE-O 3.47Å; M163-E167 HydrophobicContact CG-CB 3.81Å; M163-V168 HydrophobicContact CB-CG2 3.92Å; M163-V168 HydrophobicContact CE-CG2 4.15Å; M163-V168 HydrophobicContact CG-CG2 3.57Å; M163-V168 HydrophobicContact SD-CB 4.34Å; M163-V168 HydrophobicContact SD-CG2 3.35Å; M163-V168 WeakPolarHBondContact SD-CG2 3.15Å; M163-Y171 VanDerWaalsContact CE-CB 3.41Å; M163-Y171 HydrophobicContact CE-CD2 4.3Å; M163-Y171 HydrophobicContact CE-CG 3.88Å; M163-W190 HydrophobicContact CE-CH2 4.08Å; M163-W190 HydrophobicContact CE-CZ3 4.04Å
164T95.1Very high93.3Very high49 Ų4960.3 Ų60.330%0.30132%0.315SS..  trans-88.2164.4167.869.20000110.6S166 E167 V168T164-S166 VanDerWaalsContact C-N 3.32Å; T164-S166 PolarHBondContact O-N 3.42Å; T164-S166 PolarHBondContact OG1-OG 2.82Å; T164-E167 PolarHBondContact N-OE2 3.41Å; T164-E167 PolarHBondContact O-N 3.17Å; T164-E167 WeakPolarHBondContact OG1-CG 3.42Å; T164-E167 PolarHBondContact OG1-N 2.93Å; T164-E167 PolarHBondContact OG1-OE1 3.33Å; T164-E167 PolarHBondContact OG1-OE2 3.11Å; T164-V168 PolarHBondContact O-N 3.32Å
165E93.3Very high93.4Very high138 Ų13859.6 Ų59.665%0.64532%0.318SS*.Hα-helixtrans-57.7-45174.1-67.9-178.9-179.600111.9V158 E167 V168 M169V158-E165 HydrophobicContact CG1-CG 3.75Å; E165-E167 VanDerWaalsContact C-N 3.31Å; E165-E167 PolarHBondContact O-N 3.23Å; E165-V168 PolarHBondContact O-N 3.35Å; E165-M169 WeakPolarHBondContact O-CG 3.42Å; E165-M169 PolarHBondContact O-N 3.39Å
166S95.1Very high93.6Very high79 Ų7963.4 Ų63.455%0.55233%0.331SS*.Hα-helixtrans-60.9-40.3179.261.60000112.4T164 M169 E170T164-S166 VanDerWaalsContact C-N 3.32Å; T164-S166 PolarHBondContact O-N 3.42Å; T164-S166 PolarHBondContact OG1-OG 2.82Å; S166-M169 PolarHBondContact O-N 3.42Å; S166-E170 PolarHBondContact O-N 2.92Å
167E96.1Very high93.8Very high11 Ų1165.7 Ų65.75%0.05135%0.345CS..Hα-helixtrans-73.4-36.1179.9-67.9160.4-175.400112.2R130 Y131 M163 T164 E165 M169 E170 Y171 W190R130-E167 IonicContact CZ-OE1 3.13Å; R130-E167 IonicContact CZ-OE2 3.04Å; R130-E167 IonicContact NH1-OE1 2.79Å; R130-E167 PolarHBondContact NH1-OE1 3.4Å; R130-E167 IonicContact NH1-OE2 3.76Å; R130-E167 PolarHBondContact NH1-OE2 3Å; R130-E167 IonicContact NH2-OE1 3.64Å; R130-E167 PolarHBondContact NH2-OE1 3.24Å; R130-E167 IonicContact NH2-OE2 3.14Å; Y131-E167 HydrophobicContact CE1-CG 4.44Å; Y131-E167 WeakPolarHBondContact CE1-OE1 3.32Å; M163-E167 VanDerWaalsContact CE-C 3.41Å; M163-E167 HydrophobicContact CE-CB 3.99Å; M163-E167 WeakPolarHBondContact CE-O 3.47Å; M163-E167 HydrophobicContact CG-CB 3.81Å; T164-E167 PolarHBondContact N-OE2 3.41Å; T164-E167 PolarHBondContact O-N 3.17Å; T164-E167 WeakPolarHBondContact OG1-CG 3.42Å; T164-E167 PolarHBondContact OG1-N 2.93Å; T164-E167 PolarHBondContact OG1-OE1 3.33Å; T164-E167 PolarHBondContact OG1-OE2 3.11Å; E165-E167 VanDerWaalsContact C-N 3.31Å; E165-E167 PolarHBondContact O-N 3.23Å; E167-M169 VanDerWaalsContact C-N 3.29Å; E167-E170 PolarHBondContact O-N 2.96Å; E167-Y171 VanDerWaalsContact O-CB 3.28Å; E167-Y171 WeakPolarHBondContact O-CB 3.5Å; E167-Y171 PolarHBondContact O-N 2.97Å; E167-W190 HydrophobicContact CB-CH2 4.41Å; E167-W190 HydrophobicContact CB-CZ3 4.32Å
168V95.4Very high93.9Very high17 Ų1769.5 Ų69.510%0.10336%0.362CS..Hα-helixtrans-59.9-44.2171.1168.40000110.3W154 V158 M163 T164 E165 Y171 L172W154-V168 HydrophobicContact CB-CG1 3.96Å; V158-V168 HydrophobicContact CG2-CB 4.18Å; V158-V168 HydrophobicContact CG2-CG2 3.35Å; M163-V168 HydrophobicContact CB-CG2 3.92Å; M163-V168 HydrophobicContact CE-CG2 4.15Å; M163-V168 HydrophobicContact CG-CG2 3.57Å; M163-V168 HydrophobicContact SD-CB 4.34Å; M163-V168 HydrophobicContact SD-CG2 3.35Å; M163-V168 WeakPolarHBondContact SD-CG2 3.15Å; T164-V168 PolarHBondContact O-N 3.32Å; E165-V168 PolarHBondContact O-N 3.35Å; V168-Y171 PolarHBondContact O-N 2.83Å; V168-L172 HydrophobicContact CG1-CD1 3.59Å; V168-L172 HydrophobicContact CG1-CG 4.1Å; V168-L172 VanDerWaalsContact O-CB 3.32Å; V168-L172 WeakPolarHBondContact O-CB 3.47Å; V168-L172 WeakPolarHBondContact O-CG 3.47Å; V168-L172 PolarHBondContact O-N 2.86Å
169M95.9Very high93.9Very high131 Ų13176.6 Ų76.665%0.64539%0.391SS*.Hα-helixtrans-60-48.3177.4-68.6179.1-174.200111.5E165 S166 E167 L172 M173E165-M169 WeakPolarHBondContact O-CG 3.42Å; E165-M169 PolarHBondContact O-N 3.39Å; S166-M169 PolarHBondContact O-N 3.42Å; E167-M169 VanDerWaalsContact C-N 3.29Å; M169-L172 PolarHBondContact O-N 3.07Å; M169-M173 VanDerWaalsContact O-CB 3.31Å; M169-M173 WeakPolarHBondContact O-CB 3.38Å; M169-M173 PolarHBondContact O-N 3.1Å
170E95.7Very high94Very high95 Ų9578.5 Ų78.544%0.44440%0.402SS..Hα-helixtrans-61.3-49.4177.9-167.8179.3148.700111.5S166 E167 L172 M173 E174 W190S166-E170 PolarHBondContact O-N 2.92Å; E167-E170 PolarHBondContact O-N 2.96Å; E170-L172 PolarHBondContact O-N 2.77Å; E170-M173 WeakPolarHBondContact O-CB 3.27Å; E170-M173 PolarHBondContact O-N 3.01Å; E170-E174 WeakPolarHBondContact O-CG 3.31Å; E170-E174 PolarHBondContact O-N 3.33Å; E170-W190 HydrophobicContact CB-CZ2 4.12Å; E170-W190 HydrophobicContact CG-CZ2 3.89Å; E170-W190 PolarHBondContact OE1-NE1 2.73Å
171Y96.3Very high94.2Very high5 Ų578.3 Ų78.32%0.0240%0.401CS..Hα-helixtrans-57.7-46.8178.4-174-95.1000112.4I138 W154 M163 E167 V168 M173 E174 C175 M183 L186 P187 W190I138-Y171 HydrophobicContact CD1-CD2 4.47Å; I138-Y171 HydrophobicContact CD1-CE2 3.8Å; W154-Y171 HydrophobicContact CE3-CD1 4.42Å; W154-Y171 HydrophobicContact CE3-CE1 4.45Å; W154-Y171 HydrophobicContact CH2-CD1 4.01Å; W154-Y171 AromaticContact CH2-CE1 3.26Å; W154-Y171 HydrophobicContact CH2-CE1 3.26Å; W154-Y171 AromaticContact CH2-CZ 3.93Å; W154-Y171 HydrophobicContact CZ2-CD1 4.35Å; W154-Y171 AromaticContact CZ2-CE1 3.7Å; W154-Y171 HydrophobicContact CZ2-CE1 3.7Å; W154-Y171 HydrophobicContact CZ3-CD1 4.03Å; W154-Y171 AromaticContact CZ3-CE1 3.68Å; W154-Y171 HydrophobicContact CZ3-CE1 3.68Å; M163-Y171 VanDerWaalsContact CE-CB 3.41Å; M163-Y171 HydrophobicContact CE-CD2 4.3Å; M163-Y171 HydrophobicContact CE-CG 3.88Å; E167-Y171 VanDerWaalsContact O-CB 3.28Å; E167-Y171 WeakPolarHBondContact O-CB 3.5Å; E167-Y171 PolarHBondContact O-N 2.97Å; V168-Y171 PolarHBondContact O-N 2.83Å; Y171-M173 VanDerWaalsContact C-N 3.35Å; Y171-E174 PolarHBondContact O-N 2.89Å; Y171-C175 WeakPolarHBondContact CE1-SG 3.42Å; Y171-C175 WeakPolarHBondContact O-CB 3.5Å; Y171-C175 PolarHBondContact O-N 3.24Å; Y171-C175 PolarHBondContact O-SG 2.89Å; Y171-M183 HydrophobicContact CE2-CB 4.32Å; Y171-M183 VanDerWaalsContact CE2-O 3.24Å; Y171-M183 WeakPolarHBondContact CE2-O 3.22Å; Y171-M183 PolarHBondContact OH-O 3.38Å; Y171-L186 HydrophobicContact CD2-CB 4.33Å; Y171-L186 HydrophobicContact CD2-CD2 3.86Å; Y171-L186 HydrophobicContact CD2-CG 4.42Å; Y171-L186 HydrophobicContact CE2-CB 4.26Å; Y171-L186 HydrophobicContact CE2-CD2 4.44Å; Y171-P187 HydrophobicContact CE2-CG 4.44Å; Y171-W190 HydrophobicContact CD2-CH2 4.3Å
172L95.6Very high94.4Very high54 Ų5480.6 Ų80.628%0.28340%0.397SS..Hα-helixtrans-70.3-32.1-179.3-68.3179.9000112.5W154 V168 M169 E170 K176W154-L172 HydrophobicContact CD2-CD2 4.2Å; W154-L172 HydrophobicContact CG-CD1 4.43Å; W154-L172 HydrophobicContact CG-CD2 4.06Å; V168-L172 HydrophobicContact CG1-CD1 3.59Å; V168-L172 HydrophobicContact CG1-CG 4.1Å; V168-L172 VanDerWaalsContact O-CB 3.32Å; V168-L172 WeakPolarHBondContact O-CB 3.47Å; V168-L172 WeakPolarHBondContact O-CG 3.47Å; V168-L172 PolarHBondContact O-N 2.86Å; M169-L172 PolarHBondContact O-N 3.07Å; E170-L172 PolarHBondContact O-N 2.77Å; L172-K176 WeakPolarHBondContact O-CB 3.45Å; L172-K176 VanDerWaalsContact O-CG 3.26Å; L172-K176 WeakPolarHBondContact O-CG 3.24Å; L172-K176 PolarHBondContact O-N 2.79Å
173M96.6Very high94.6Very high128 Ų12880.8 Ų80.863%0.63140%0.398SS*.Hα-helixtrans-63.2-49172.6179170.8171.300110.7M169 E170 Y171 C175 K176 L177M169-M173 VanDerWaalsContact O-CB 3.31Å; M169-M173 WeakPolarHBondContact O-CB 3.38Å; M169-M173 PolarHBondContact O-N 3.1Å; E170-M173 WeakPolarHBondContact O-CB 3.27Å; E170-M173 PolarHBondContact O-N 3.01Å; Y171-M173 VanDerWaalsContact C-N 3.35Å; M173-C175 PolarHBondContact O-N 3Å; M173-K176 WeakPolarHBondContact O-CB 3.49Å; M173-K176 PolarHBondContact O-N 3.36Å; M173-K176 VanDerWaalsContact O-N 3.12Å; M173-L177 PolarHBondContact O-N 2.67Å
174E95.4Very high94.6Very high53 Ų5382.4 Ų82.425%0.24840%0.404CS..Hα-helixtrans-63-41.5177.4-67.6-56.1142.900112.4E170 Y171 K176 L177 H178 L186E170-E174 WeakPolarHBondContact O-CG 3.31Å; E170-E174 PolarHBondContact O-N 3.33Å; Y171-E174 PolarHBondContact O-N 2.89Å; E174-K176 VanDerWaalsContact C-N 3.28Å; E174-K176 PolarHBondContact O-N 2.88Å; E174-L177 PolarHBondContact O-N 2.76Å; E174-H178 PolarHBondContact O-N 3.36Å; E174-H178 IonicContact OE2-CD2 3.32Å; E174-H178 PolarHBondContact OE2-CD2 3.39Å; E174-H178 IonicContact OE2-NE2 2.8Å; E174-L186 HydrophobicContact CB-CD2 3.76Å; E174-L186 HydrophobicContact CG-CD2 3.88Å
175C93.2Very high94.6Very high38 Ų3883.7 Ų83.726%0.25741%0.406SS..Hα-helixtrans-60-36.8172.9-73.60000112.8Y171 M173Y171-C175 WeakPolarHBondContact CE1-SG 3.42Å; Y171-C175 WeakPolarHBondContact O-CB 3.5Å; Y171-C175 PolarHBondContact O-N 3.24Å; Y171-C175 PolarHBondContact O-SG 2.89Å; M173-C175 PolarHBondContact O-N 3Å
176K94.3Very high94.7Very high155 Ų15578 Ų7867%0.67438%0.38SS*.Hα-helixtrans-72.7-35.3177.1-77.3173.8-178.1179.90112.2L172 M173 E174 K179L172-K176 WeakPolarHBondContact O-CB 3.45Å; L172-K176 VanDerWaalsContact O-CG 3.26Å; L172-K176 WeakPolarHBondContact O-CG 3.24Å; L172-K176 PolarHBondContact O-N 2.79Å; M173-K176 WeakPolarHBondContact O-CB 3.49Å; M173-K176 PolarHBondContact O-N 3.36Å; M173-K176 VanDerWaalsContact O-N 3.12Å; E174-K176 VanDerWaalsContact C-N 3.28Å; E174-K176 PolarHBondContact O-N 2.88Å; K176-K179 VanDerWaalsContact O-CE 3.3Å; K176-K179 WeakPolarHBondContact O-CE 3.27Å; K176-K179 VanDerWaalsContact O-CG 3.3Å; K176-K179 WeakPolarHBondContact O-CG 3.43Å
177L96.6Very high94.9Very high114 Ų11474.3 Ų74.360%0.59735%0.354SS*.Hα-helixtrans-71.1-40.8178.4-175.960.5000111.3M173 E174M173-L177 PolarHBondContact O-N 2.67Å; E174-L177 PolarHBondContact O-N 2.76Å
178H94.6Very high94.9Very high81 Ų8174 Ų7438%0.37535%0.353SS..  trans-115.660.8-174.6-61.7-67.6000112.2E174 E180 V181 M183E174-H178 PolarHBondContact O-N 3.36Å; E174-H178 IonicContact OE2-CD2 3.32Å; E174-H178 PolarHBondContact OE2-CD2 3.39Å; E174-H178 IonicContact OE2-NE2 2.8Å; H178-E180 PolarHBondContact O-N 3.06Å; H178-V181 HydrophobicContact CB-CB 4.19Å; H178-V181 HydrophobicContact CB-CG2 4.29Å; H178-V181 PolarHBondContact O-N 3.3Å; H178-M183 HydrophobicContact CB-CE 3.26Å; H178-M183 WeakPolarHBondContact CD2-CE 3.49Å; H178-M183 VanDerWaalsContact CG-CE 3.46Å
179K90.9Very high95Very high179 Ų17977.3 Ų77.378%0.77837%0.367SS*.THydrogen-bonded Turntrans-58.6-23.9-173.4-61.3-179.5-177.2172.20115K176 V181K176-K179 VanDerWaalsContact O-CE 3.3Å; K176-K179 WeakPolarHBondContact O-CE 3.27Å; K176-K179 VanDerWaalsContact O-CG 3.3Å; K176-K179 WeakPolarHBondContact O-CG 3.43Å; K179-V181 VanDerWaalsContact C-N 3.34Å
180E92.2Very high95.1Very high195 Ų19572.1 Ų72.191%0.91134%0.34SS*.THydrogen-bonded Turntrans-85.7-8.6-179.8-61.4179.1177.600112.9H178H178-E180 PolarHBondContact O-N 3.06Å
181V92.9Very high95.3Very high69 Ų6967.6 Ų67.642%0.41832%0.319SS..SBendtrans-109.4125-175-178.10000109.9H178 K179 M183 F185H178-V181 HydrophobicContact CB-CB 4.19Å; H178-V181 HydrophobicContact CB-CG2 4.29Å; H178-V181 PolarHBondContact O-N 3.3Å; K179-V181 VanDerWaalsContact C-N 3.34Å; V181-M183 HydrophobicContact CB-CE 4.22Å; V181-M183 HydrophobicContact CG1-CE 4.12Å; V181-M183 HydrophobicContact CG1-SD 4.03Å; V181-M183 PolarHBondContact O-N 2.84Å; V181-F185 HydrophobicContact CG1-CE1 3.8Å; V181-F185 HydrophobicContact CG1-CZ 4.34Å
182Y92.9Very high95.3Very high89 Ų8968.1 Ų68.135%0.34932%0.323SS..  trans-7498.4170.9-178.5-146.9000110.4D142 Y184 I228D142-Y182 PolarHBondContact OD2-OH 2.9Å; Y182-Y184 AromaticContact CD1-CD1 3.41Å; Y182-Y184 HydrophobicContact CD1-CD1 3.41Å; Y182-Y184 VanDerWaalsContact CD1-CD1 3.41Å; Y182-Y184 HydrophobicContact CD1-CE1 4.2Å; Y182-Y184 HydrophobicContact CD1-CG 4.13Å; Y182-Y184 AromaticContact CE1-CD1 3.65Å; Y182-Y184 HydrophobicContact CE1-CD1 3.65Å; Y182-Y184 AromaticContact CE1-CG 3.91Å; Y182-Y184 HydrophobicContact CE1-CG 3.91Å; Y182-Y184 AromaticContact CG-CD1 3.96Å; Y182-Y184 HydrophobicContact CG-CD1 3.96Å; Y182-Y184 WeakPolarHBondContact O-CD1 3.2Å; Y182-Y184 PolarHBondContact O-N 3.45Å; Y182-I228 HydrophobicContact CD1-CD1 4.31Å; Y182-I228 HydrophobicContact CE1-CD1 3.77Å; Y182-I228 HydrophobicContact CE1-CG1 4.15Å; Y182-I228 HydrophobicContact CE1-CG2 4.49Å
183M94.7Very high95.4Very high13 Ų1369.6 Ų69.66%0.06433%0.331CS..G310 helixtrans-74.223.7-172.8-73.3-63.7-170.400115.3Y171 H178 V181 F185 L186Y171-M183 HydrophobicContact CE2-CB 4.32Å; Y171-M183 VanDerWaalsContact CE2-O 3.24Å; Y171-M183 WeakPolarHBondContact CE2-O 3.22Å; Y171-M183 PolarHBondContact OH-O 3.38Å; H178-M183 HydrophobicContact CB-CE 3.26Å; H178-M183 WeakPolarHBondContact CD2-CE 3.49Å; H178-M183 VanDerWaalsContact CG-CE 3.46Å; V181-M183 HydrophobicContact CB-CE 4.22Å; V181-M183 HydrophobicContact CG1-CE 4.12Å; V181-M183 HydrophobicContact CG1-SD 4.03Å; V181-M183 PolarHBondContact O-N 2.84Å; M183-F185 PolarHBondContact O-N 3.25Å; M183-F185 VanDerWaalsContact O-N 3.12Å; M183-F185 HydrophobicContact SD-CE1 3.81Å; M183-F185 HydrophobicContact SD-CZ 3.65Å; M183-L186 WeakPolarHBondContact O-CB 3.49Å; M183-L186 PolarHBondContact O-N 3.2Å; M183-L186 VanDerWaalsContact O-N 3.16Å
184Y93.4Very high95.5Very high37 Ų3764.6 Ų64.615%0.14531%0.307CS..G310 helixtrans-58.1-27.817880.6-86.1000113.3C135 V139 Y182 L186 P187 V224 I228C135-Y184 PolarHBondContact SG-O 2.82Å; C135-Y184 VanDerWaalsContact SG-O 3.41Å; V139-Y184 HydrophobicContact CG2-CD2 3.55Å; V139-Y184 HydrophobicContact CG2-CE2 4.47Å; V139-Y184 HydrophobicContact CG2-CG 3.9Å; Y182-Y184 AromaticContact CD1-CD1 3.41Å; Y182-Y184 HydrophobicContact CD1-CD1 3.41Å; Y182-Y184 VanDerWaalsContact CD1-CD1 3.41Å; Y182-Y184 HydrophobicContact CD1-CE1 4.2Å; Y182-Y184 HydrophobicContact CD1-CG 4.13Å; Y182-Y184 AromaticContact CE1-CD1 3.65Å; Y182-Y184 HydrophobicContact CE1-CD1 3.65Å; Y182-Y184 AromaticContact CE1-CG 3.91Å; Y182-Y184 HydrophobicContact CE1-CG 3.91Å; Y182-Y184 AromaticContact CG-CD1 3.96Å; Y182-Y184 HydrophobicContact CG-CD1 3.96Å; Y182-Y184 WeakPolarHBondContact O-CD1 3.2Å; Y182-Y184 PolarHBondContact O-N 3.45Å; Y184-L186 VanDerWaalsContact C-N 3.34Å; Y184-P187 WeakPolarHBondContact O-CD 3.5Å; Y184-V224 HydrophobicContact CD2-CG2 4.24Å; Y184-V224 HydrophobicContact CE2-CG2 3.82Å; Y184-I228 HydrophobicContact CD1-CD1 3.64Å; Y184-I228 HydrophobicContact CD2-CD1 3.69Å; Y184-I228 HydrophobicContact CE1-CD1 3.57Å; Y184-I228 HydrophobicContact CE2-CD1 3.63Å; Y184-I228 HydrophobicContact CG-CD1 3.7Å
185F94.8Very high95.6Very high77 Ų7762.1 Ų62.134%0.33830%0.296SS..G310 helixtrans-79.6-14.5-176.670-91.9000113.2V181 M183 L188 Q189V181-F185 HydrophobicContact CG1-CE1 3.8Å; V181-F185 HydrophobicContact CG1-CZ 4.34Å; M183-F185 PolarHBondContact O-N 3.25Å; M183-F185 VanDerWaalsContact O-N 3.12Å; M183-F185 HydrophobicContact SD-CE1 3.81Å; M183-F185 HydrophobicContact SD-CZ 3.65Å; F185-L188 WeakPolarHBondContact O-CA 3.44Å; F185-L188 WeakPolarHBondContact O-CB 3.22Å; F185-L188 PolarHBondContact O-N 2.99Å; F185-Q189 PolarHBondContact O-N 3.45Å
186L97.2Very high95.7Very high19 Ų1962.6 Ų62.610%0.09930%0.297CS..Hα-helixtrans-56.8-43.9-173.4177.860.4000112.9Y171 E174 M183 Y184 L188 Q189 W190Y171-L186 HydrophobicContact CD2-CB 4.33Å; Y171-L186 HydrophobicContact CD2-CD2 3.86Å; Y171-L186 HydrophobicContact CD2-CG 4.42Å; Y171-L186 HydrophobicContact CE2-CB 4.26Å; Y171-L186 HydrophobicContact CE2-CD2 4.44Å; E174-L186 HydrophobicContact CB-CD2 3.76Å; E174-L186 HydrophobicContact CG-CD2 3.88Å; M183-L186 WeakPolarHBondContact O-CB 3.49Å; M183-L186 PolarHBondContact O-N 3.2Å; M183-L186 VanDerWaalsContact O-N 3.16Å; Y184-L186 VanDerWaalsContact C-N 3.34Å; L186-L188 VanDerWaalsContact C-N 3.28Å; L186-L188 PolarHBondContact O-N 3.39Å; L186-Q189 CarbonylContact O-C 3.26Å; L186-Q189 WeakPolarHBondContact O-CA 3.3Å; L186-Q189 WeakPolarHBondContact O-CB 3.43Å; L186-Q189 PolarHBondContact O-N 2.85Å; L186-W190 HydrophobicContact CD1-CZ2 4.31Å; L186-W190 HydrophobicContact CD2-CH2 4.3Å; L186-W190 HydrophobicContact CD2-CZ2 3.67Å; L186-W190 HydrophobicContact CG-CD2 4.23Å; L186-W190 HydrophobicContact CG-CH2 4.36Å; L186-W190 HydrophobicContact CG-CZ2 3.71Å; L186-W190 PolarHBondContact O-N 3.31Å
187P97.9Very high95.8Very high0 Ų060.4 Ų60.40%029%0.288CS..Hα-helixtrans-60.9-32.4172.7-24.635.1000114.2Y131 L134 C135 I138 Y171 Y184 Q189 W190 A191Y131-P187 WeakPolarHBondContact O-CB 3.13Å; L134-P187 HydrophobicContact CB-CB 4.39Å; L134-P187 HydrophobicContact CD2-CB 4.08Å; L134-P187 HydrophobicContact CD2-CG 3.87Å; L134-P187 HydrophobicContact CG-CB 4.21Å; L134-P187 HydrophobicContact CG-CG 3.92Å; C135-P187 HydrophobicContact CB-CB 4.22Å; I138-P187 HydrophobicContact CD1-CG 3.9Å; Y171-P187 HydrophobicContact CE2-CG 4.44Å; Y184-P187 WeakPolarHBondContact O-CD 3.5Å; P187-Q189 VanDerWaalsContact C-N 3.34Å; P187-W190 HydrophobicContact CB-CE3 4.14Å; P187-W190 HydrophobicContact CG-CE3 4.3Å; P187-W190 HydrophobicContact CG-CZ3 4.28Å; P187-W190 PolarHBondContact O-N 2.89Å; P187-A191 WeakPolarHBondContact O-CB 3.23Å; P187-A191 PolarHBondContact O-N 3.38Å
188L97.2Very high95.9Very high5 Ų555 Ų553%0.02626%0.259CS..Hα-helixtrans-70.5-33.6173-61-175000111.6I132 C135 F185 L186 A191 C192 I217 R221I132-L188 HydrophobicContact CD1-CD2 3.64Å; C135-L188 HydrophobicContact CB-CD1 4.4Å; C135-L188 HydrophobicContact CB-CD2 3.66Å; C135-L188 HydrophobicContact CB-CG 3.7Å; C135-L188 VanDerWaalsContact SG-CG 3.51Å; F185-L188 WeakPolarHBondContact O-CA 3.44Å; F185-L188 WeakPolarHBondContact O-CB 3.22Å; F185-L188 PolarHBondContact O-N 2.99Å; L186-L188 VanDerWaalsContact C-N 3.28Å; L186-L188 PolarHBondContact O-N 3.39Å; L188-A191 WeakPolarHBondContact O-CB 3.34Å; L188-A191 PolarHBondContact O-N 3.26Å; L188-C192 PolarHBondContact O-N 3.4Å; L188-C192 PolarHBondContact O-SG 3.39Å; L188-C192 VanDerWaalsContact O-SG 3.37Å; L188-I217 HydrophobicContact CB-CG2 4.19Å; L188-I217 HydrophobicContact CD2-CG2 4.14Å; L188-R221 HydrophobicContact CD1-CB 3.66Å; L188-R221 HydrophobicContact CD1-CG 3.99Å
189Q97.2Very high95.9Very high87 Ų8754.4 Ų54.441%0.40725%0.254SS..Hα-helixtrans-66.5-43172.8-172.158.245.500111.2F185 L186 P187 A191 C192 N193F185-Q189 PolarHBondContact O-N 3.45Å; L186-Q189 CarbonylContact O-C 3.26Å; L186-Q189 WeakPolarHBondContact O-CA 3.3Å; L186-Q189 WeakPolarHBondContact O-CB 3.43Å; L186-Q189 PolarHBondContact O-N 2.85Å; P187-Q189 VanDerWaalsContact C-N 3.34Å; Q189-A191 VanDerWaalsContact C-N 3.28Å; Q189-A191 PolarHBondContact O-N 3.2Å; Q189-C192 WeakPolarHBondContact O-CB 3.48Å; Q189-C192 PolarHBondContact O-N 3.05Å; Q189-N193 PolarHBondContact NE2-OD1 3.4Å; Q189-N193 VanDerWaalsContact O-CG 3.26Å; Q189-N193 PolarHBondContact O-N 3.18Å; Q189-N193 PolarHBondContact O-OD1 3.26Å
190W98.4Very high96.2Very high21 Ų2154 Ų548%0.0825%0.252CS..Hα-helixtrans-59.1-40.4171.1-63.2-31.3000111.8Y131 L134 M163 E167 E170 Y171 L186 P187 N193 L194Y131-W190 HydrophobicContact CD1-CE3 4.38Å; Y131-W190 HydrophobicContact CD2-CB 3.72Å; Y131-W190 HydrophobicContact CE1-CE3 4.23Å; Y131-W190 HydrophobicContact CE2-CB 3.6Å; Y131-W190 HydrophobicContact CG-CB 4.4Å; L134-W190 HydrophobicContact CD2-CZ3 4.32Å; M163-W190 HydrophobicContact CE-CH2 4.08Å; M163-W190 HydrophobicContact CE-CZ3 4.04Å; E167-W190 HydrophobicContact CB-CH2 4.41Å; E167-W190 HydrophobicContact CB-CZ3 4.32Å; E170-W190 HydrophobicContact CB-CZ2 4.12Å; E170-W190 HydrophobicContact CG-CZ2 3.89Å; E170-W190 PolarHBondContact OE1-NE1 2.73Å; Y171-W190 HydrophobicContact CD2-CH2 4.3Å; L186-W190 HydrophobicContact CD1-CZ2 4.31Å; L186-W190 HydrophobicContact CD2-CH2 4.3Å; L186-W190 HydrophobicContact CD2-CZ2 3.67Å; L186-W190 HydrophobicContact CG-CD2 4.23Å; L186-W190 HydrophobicContact CG-CH2 4.36Å; L186-W190 HydrophobicContact CG-CZ2 3.71Å; L186-W190 PolarHBondContact O-N 3.31Å; P187-W190 HydrophobicContact CB-CE3 4.14Å; P187-W190 HydrophobicContact CG-CE3 4.3Å; P187-W190 HydrophobicContact CG-CZ3 4.28Å; P187-W190 PolarHBondContact O-N 2.89Å; W190-N193 PolarHBondContact O-N 3.32Å; W190-L194 VanDerWaalsContact O-CB 3.27Å; W190-L194 WeakPolarHBondContact O-CB 3.49Å; W190-L194 PolarHBondContact O-N 2.85Å
191A98.2Very high96.3Very high0 Ų047.7 Ų47.70%022%0.223CC..Hα-helixtrans-61-46.3174.100000112L128 Y131 I132 P187 L188 Q189 N193 L194 V195 I217L128-A191 HydrophobicContact CD1-CB 3.62Å; Y131-A191 HydrophobicContact CD2-CB 4.4Å; I132-A191 HydrophobicContact CD1-CB 4.09Å; P187-A191 WeakPolarHBondContact O-CB 3.23Å; P187-A191 PolarHBondContact O-N 3.38Å; L188-A191 WeakPolarHBondContact O-CB 3.34Å; L188-A191 PolarHBondContact O-N 3.26Å; Q189-A191 VanDerWaalsContact C-N 3.28Å; Q189-A191 PolarHBondContact O-N 3.2Å; A191-N193 PolarHBondContact O-N 2.99Å; A191-L194 PolarHBondContact O-N 3.4Å; A191-V195 WeakPolarHBondContact O-CG2 3.45Å; A191-V195 PolarHBondContact O-N 3.17Å; A191-I217 HydrophobicContact CB-CD1 4.07Å
192C97.6Very high96.4Very high16 Ų1652.2 Ų52.211%0.10824%0.239CC..Hα-helixtrans-58.8-46.6174.3-72.40000111.7L188 Q189 L194 V195 V196L188-C192 PolarHBondContact O-N 3.4Å; L188-C192 PolarHBondContact O-SG 3.39Å; L188-C192 VanDerWaalsContact O-SG 3.37Å; Q189-C192 WeakPolarHBondContact O-CB 3.48Å; Q189-C192 PolarHBondContact O-N 3.05Å; C192-L194 VanDerWaalsContact C-N 3.33Å; C192-L194 PolarHBondContact O-N 2.86Å; C192-V195 WeakPolarHBondContact O-CB 3.31Å; C192-V195 PolarHBondContact O-N 3.47Å; C192-V196 WeakPolarHBondContact O-CG2 3.14Å; C192-V196 PolarHBondContact O-N 3.38Å
193N97.9Very high96.5Very high85 Ų8550.8 Ų50.846%0.45523%0.233SC..Hα-helixtrans-63.8-38.8178.5-67.6-9.3000111.6Q189 W190 A191 V195 V196 K197Q189-N193 PolarHBondContact NE2-OD1 3.4Å; Q189-N193 VanDerWaalsContact O-CG 3.26Å; Q189-N193 PolarHBondContact O-N 3.18Å; Q189-N193 PolarHBondContact O-OD1 3.26Å; W190-N193 PolarHBondContact O-N 3.32Å; A191-N193 PolarHBondContact O-N 2.99Å; N193-V195 VanDerWaalsContact C-N 3.33Å; N193-V196 PolarHBondContact O-N 3.14Å; N193-K197 WeakPolarHBondContact O-CB 3.28Å; N193-K197 PolarHBondContact O-N 2.86Å
194L97.2Very high96.6Very high24 Ų2450.1 Ų50.113%0.12623%0.23CC..Hα-helixtrans-64.3-38.6176-171.369.6000111.6L124 T127 L128 Y131 W190 A191 C192 K197 A198L124-L194 HydrophobicContact CD2-CD1 3.71Å; L124-L194 HydrophobicContact CD2-CG 4.21Å; T127-L194 HydrophobicContact CG2-CD2 3.74Å; L128-L194 HydrophobicContact CB-CD2 3.99Å; Y131-L194 HydrophobicContact CD2-CD2 4.32Å; Y131-L194 HydrophobicContact CE2-CD2 4.24Å; W190-L194 VanDerWaalsContact O-CB 3.27Å; W190-L194 WeakPolarHBondContact O-CB 3.49Å; W190-L194 PolarHBondContact O-N 2.85Å; A191-L194 PolarHBondContact O-N 3.4Å; C192-L194 VanDerWaalsContact C-N 3.33Å; C192-L194 PolarHBondContact O-N 2.86Å; L194-K197 PolarHBondContact O-N 2.69Å; L194-A198 WeakPolarHBondContact O-CB 3.17Å; L194-A198 PolarHBondContact O-N 2.9Å
195V97.7Very high96.3Very high0 Ų052.1 Ų52.10%024%0.243CC..Hα-helixtrans-64.8-44.2174.5167.40000111.3L128 A191 C192 N193 K197 A198 R199 I204 M210 L213 M214 I217L128-V195 HydrophobicContact CD1-CG2 4.14Å; L128-V195 HydrophobicContact CD2-CG2 4.12Å; A191-V195 WeakPolarHBondContact O-CG2 3.45Å; A191-V195 PolarHBondContact O-N 3.17Å; C192-V195 WeakPolarHBondContact O-CB 3.31Å; C192-V195 PolarHBondContact O-N 3.47Å; N193-V195 VanDerWaalsContact C-N 3.33Å; V195-K197 VanDerWaalsContact C-N 3.32Å; V195-K197 PolarHBondContact O-N 2.84Å; V195-A198 PolarHBondContact O-N 3.42Å; V195-R199 PolarHBondContact O-N 3.34Å; V195-I204 HydrophobicContact CG1-CD1 3.94Å; V195-M210 HydrophobicContact CG1-CG 3.55Å; V195-L213 HydrophobicContact CB-CD2 4.38Å; V195-L213 HydrophobicContact CG1-CB 4.4Å; V195-L213 HydrophobicContact CG1-CD2 4.05Å; V195-L213 HydrophobicContact CG1-CG 4.48Å; V195-L213 HydrophobicContact CG2-CD2 3.45Å; V195-L213 VanDerWaalsContact CG2-CD2 3.45Å; V195-L213 HydrophobicContact CG2-CG 3.88Å; V195-M214 HydrophobicContact CG1-CE 4.32Å; V195-M214 HydrophobicContact CG1-CG 4.28Å; V195-I217 HydrophobicContact CG2-CD1 4.06Å
196V96.8Very high96Very high49 Ų4949.2 Ų49.230%0.29723%0.232SC..Hα-helixtrans-62.3-41.4173.9174.40000111C192 N193 R199 K200 M210 M214C192-V196 WeakPolarHBondContact O-CG2 3.14Å; C192-V196 PolarHBondContact O-N 3.38Å; N193-V196 PolarHBondContact O-N 3.14Å; V196-R199 PolarHBondContact O-N 3.23Å; V196-K200 HydrophobicContact CG1-CD 4.49Å; V196-K200 WeakPolarHBondContact O-CG 3.31Å; V196-K200 PolarHBondContact O-N 3.4Å; V196-M210 HydrophobicContact CG2-SD 4.4Å; V196-M214 HydrophobicContact CG2-CE 3.43Å; V196-M214 VanDerWaalsContact CG2-CE 3.43Å
197K96.3Very high95.7Very high108 Ų10852.6 Ų52.647%0.4725%0.251SS..Hα-helixtrans-63.3-45.8176.4-173.6175.1-176.7176.20111.6N193 L194 V195 R199 K200 E201N193-K197 WeakPolarHBondContact O-CB 3.28Å; N193-K197 PolarHBondContact O-N 2.86Å; L194-K197 PolarHBondContact O-N 2.69Å; V195-K197 VanDerWaalsContact C-N 3.32Å; V195-K197 PolarHBondContact O-N 2.84Å; K197-R199 PolarHBondContact O-N 2.72Å; K197-K200 PolarHBondContact O-N 3.31Å; K197-K200 VanDerWaalsContact O-N 3.15Å; K197-E201 WeakPolarHBondContact CE-OE1 3.2Å; K197-E201 WeakPolarHBondContact CG-OE1 3.3Å; K197-E201 WeakPolarHBondContact O-CB 3.37Å; K197-E201 WeakPolarHBondContact O-CG 3.34Å; K197-E201 PolarHBondContact O-N 2.94Å
198A97.3Very high95.4Very high0 Ų055 Ų550%026%0.263CS..Hα-helixtrans-60.4-35.1175.700000112.1L124 L194 V195 E201 E202 R203 I204L124-A198 HydrophobicContact CD1-CB 4.01Å; L124-A198 HydrophobicContact CD2-CB 4.37Å; L194-A198 WeakPolarHBondContact O-CB 3.17Å; L194-A198 PolarHBondContact O-N 2.9Å; V195-A198 PolarHBondContact O-N 3.42Å; A198-E201 PolarHBondContact O-N 2.98Å; A198-E202 PolarHBondContact O-N 3.22Å; A198-R203 HydrophobicContact CB-CB 4.38Å; A198-R203 WeakPolarHBondContact O-CA 3.19Å; A198-R203 WeakPolarHBondContact O-CB 3.49Å; A198-R203 PolarHBondContact O-N 2.92Å; A198-I204 HydrophobicContact CB-CD1 3.98Å; A198-I204 HydrophobicContact CB-CG1 4.07Å; A198-I204 PolarHBondContact O-N 3.32Å
199R96Very high95Very high70 Ų7055 Ų5526%0.26426%0.263SS..Hα-helixtrans-67.4-44.3172.9-179.557.7-179.5135.46.3112.5V195 V196 K197 E201 E202 I204 D205 D207 M210V195-R199 PolarHBondContact O-N 3.34Å; V196-R199 PolarHBondContact O-N 3.23Å; K197-R199 PolarHBondContact O-N 2.72Å; R199-E201 VanDerWaalsContact C-N 3.26Å; R199-E201 PolarHBondContact O-N 2.82Å; R199-E202 PolarHBondContact O-N 3.21Å; R199-I204 HydrophobicContact CB-CB 4.3Å; R199-I204 HydrophobicContact CB-CD1 4.5Å; R199-I204 WeakPolarHBondContact CD-O 3.11Å; R199-I204 PolarHBondContact NH1-O 2.95Å; R199-D205 PolarHBondContact NH1-O 3.19Å; R199-D205 VanDerWaalsContact NH1-O 3.07Å; R199-D207 IonicContact CZ-OD1 2.96Å; R199-D207 VanDerWaalsContact CZ-OD1 3.3Å; R199-D207 IonicContact NE-OD1 3.3Å; R199-D207 PolarHBondContact NE-OD1 3.4Å; R199-D207 IonicContact NH2-OD1 3.93Å; R199-D207 PolarHBondContact NH2-OD1 3.47Å; R199-M210 HydrophobicContact CB-CG 4.37Å; R199-M210 HydrophobicContact CB-SD 3.73Å; R199-M210 HydrophobicContact CG-SD 3.8Å
200K95.9Very high94.8Very high170 Ų17052.3 Ų52.374%0.73925%0.251SS*.Hα-helixtrans-63.1-32.4174.8-70.9179.2178.2-175.90112.9V196 K197 E202V196-K200 HydrophobicContact CG1-CD 4.49Å; V196-K200 WeakPolarHBondContact O-CG 3.31Å; V196-K200 PolarHBondContact O-N 3.4Å; K197-K200 PolarHBondContact O-N 3.31Å; K197-K200 VanDerWaalsContact O-N 3.15Å; K200-E202 PolarHBondContact O-N 2.85Å
201E95.5Very high94.6Very high62 Ų6254.4 Ų54.429%0.2927%0.266SS..THydrogen-bonded Turntrans-80.18.4173.7-68.9176.3-165.500113R120 K197 A198 R199 R203R120-E201 IonicContact CZ-OE1 2.66Å; R120-E201 IonicContact CZ-OE2 3.32Å; R120-E201 IonicContact NE-OE1 3.32Å; R120-E201 IonicContact NE-OE2 2.82Å; R120-E201 PolarHBondContact NE-OE2 3.29Å; R120-E201 IonicContact NH2-OE1 3.72Å; R120-E201 PolarHBondContact NH2-OE1 3.14Å; R120-E201 IonicContact NH2-OE2 3.04Å; R120-E201 PolarHBondContact NH2-OE2 2.93Å; K197-E201 WeakPolarHBondContact CE-OE1 3.2Å; K197-E201 WeakPolarHBondContact CG-OE1 3.3Å; K197-E201 WeakPolarHBondContact O-CB 3.37Å; K197-E201 WeakPolarHBondContact O-CG 3.34Å; K197-E201 PolarHBondContact O-N 2.94Å; A198-E201 PolarHBondContact O-N 2.98Å; R199-E201 VanDerWaalsContact C-N 3.26Å; R199-E201 PolarHBondContact O-N 2.82Å; E201-R203 HydrophobicContact CB-CG 4.01Å; E201-R203 PolarHBondContact O-N 2.89Å
202E95.3Very high94.2Very high165 Ų16555.8 Ų55.877%0.77127%0.272SS*.THydrogen-bonded Turntrans56.320.5-178.9-57-177.7167.400114A198 R199 K200 I204A198-E202 PolarHBondContact O-N 3.22Å; R199-E202 PolarHBondContact O-N 3.21Å; K200-E202 PolarHBondContact O-N 2.85Å; E202-I204 VanDerWaalsContact C-N 3.33Å
203R95.1Very high94Very high58 Ų5855 Ų5522%0.21927%0.267CS..  trans-80.3-19.7173.8-58.4-56-171.1137.8-0.6112.4H115 D118 L124 A198 E201H115-R203 WeakPolarHBondContact CB-O 3.33Å; H115-R203 PolarHBondContact CD2-O 3.07Å; H115-R203 PolarHBondContact N-O 3.01Å; D118-R203 IonicContact OD1-CZ 3.47Å; D118-R203 IonicContact OD1-NH1 3.52Å; D118-R203 PolarHBondContact OD1-NH1 2.68Å; D118-R203 IonicContact OD1-NH2 2.68Å; D118-R203 IonicContact OD2-CZ 3.52Å; D118-R203 IonicContact OD2-NH1 3.56Å; D118-R203 PolarHBondContact OD2-NH1 2.92Å; D118-R203 IonicContact OD2-NH2 3.55Å; D118-R203 PolarHBondContact OD2-NH2 2.77Å; L124-R203 HydrophobicContact CD1-CB 3.97Å; L124-R203 HydrophobicContact CD1-CG 3.7Å; A198-R203 HydrophobicContact CB-CB 4.38Å; A198-R203 WeakPolarHBondContact O-CA 3.19Å; A198-R203 WeakPolarHBondContact O-CB 3.49Å; A198-R203 PolarHBondContact O-N 2.92Å; E201-R203 HydrophobicContact CB-CG 4.01Å; E201-R203 PolarHBondContact O-N 2.89Å
204I95Very high93.8Very high0 Ų053.3 Ų53.30%026%0.257CS..SBendtrans-107121.6166.6-57.2176.9000106.6I114 V195 A198 R199 E202 S206 M209 M210 L213I114-I204 HydrophobicContact CG1-CD1 4.33Å; I114-I204 HydrophobicContact CG1-CG1 4.17Å; V195-I204 HydrophobicContact CG1-CD1 3.94Å; A198-I204 HydrophobicContact CB-CD1 3.98Å; A198-I204 HydrophobicContact CB-CG1 4.07Å; A198-I204 PolarHBondContact O-N 3.32Å; R199-I204 HydrophobicContact CB-CB 4.3Å; R199-I204 HydrophobicContact CB-CD1 4.5Å; R199-I204 WeakPolarHBondContact CD-O 3.11Å; R199-I204 PolarHBondContact NH1-O 2.95Å; E202-I204 VanDerWaalsContact C-N 3.33Å; I204-S206 WeakPolarHBondContact CG2-O 3.25Å; I204-M209 HydrophobicContact CG2-CB 3.82Å; I204-M210 HydrophobicContact CG2-CB 4.25Å; I204-L213 HydrophobicContact CD1-CD2 4.3Å
205D87.5Confident93.7Very high78 Ų7856.4 Ų56.442%0.41727%0.27SS..  trans-67.8-40.5-173391.8000113.4H115 R199H115-D205 IonicContact CD2-OD2 3.83Å; H115-D205 IonicContact CE1-OD2 3.7Å; H115-D205 IonicContact NE2-OD1 3.74Å; H115-D205 IonicContact NE2-OD2 3.34Å; H115-D205 PolarHBondContact NE2-OD2 2.93Å; R199-D205 PolarHBondContact NH1-O 3.19Å; R199-D205 VanDerWaalsContact NH1-O 3.07Å
206S88.8Confident93.5Very high16 Ų1656.9 Ų56.911%0.11227%0.273CS..  trans-139.1153.5179.270.10000114.8I204 L208 M209 M210 D581I204-S206 WeakPolarHBondContact CG2-O 3.25Å; S206-L208 PolarHBondContact O-N 3.41Å; S206-M209 WeakPolarHBondContact O-CB 3.34Å; S206-M209 PolarHBondContact O-N 3.34Å; S206-M210 PolarHBondContact O-N 2.64Å; S206-M210 VanDerWaalsContact O-N 3.16Å; S206-D581 VanDerWaalsContact CB-OD2 3.24Å; S206-D581 WeakPolarHBondContact CB-OD2 3.4Å; S206-D581 PolarHBondContact OG-OD2 3.08Å
207D91.2Very high93.4Very high91 Ų9154.5 Ų54.549%0.48726%0.258SS..Hα-helixtrans-61-29.7178.3-63-13.4000111.5R199 M209 M210 V211R199-D207 IonicContact CZ-OD1 2.96Å; R199-D207 VanDerWaalsContact CZ-OD1 3.3Å; R199-D207 IonicContact NE-OD1 3.3Å; R199-D207 PolarHBondContact NE-OD1 3.4Å; R199-D207 IonicContact NH2-OD1 3.93Å; R199-D207 PolarHBondContact NH2-OD1 3.47Å; D207-M209 VanDerWaalsContact C-N 3.33Å; D207-M209 PolarHBondContact O-N 3.38Å; D207-M210 WeakPolarHBondContact O-CB 3.33Å; D207-M210 PolarHBondContact O-N 2.82Å; D207-V211 WeakPolarHBondContact O-CG2 3.38Å; D207-V211 PolarHBondContact O-N 2.67Å
208L90.5Very high93.4Very high50 Ų5052.5 Ų52.526%0.26225%0.251SS..Hα-helixtrans-59.8-43.6173.6-177.260.4000111.6S206 K212 D581 K585S206-L208 PolarHBondContact O-N 3.41Å; L208-K212 WeakPolarHBondContact O-CB 3.12Å; L208-K212 WeakPolarHBondContact O-CG 3.39Å; L208-K212 PolarHBondContact O-N 3.42Å; L208-K212 VanDerWaalsContact O-N 3.07Å; L208-D581 HydrophobicContact CD2-CB 4.1Å; L208-K585 HydrophobicContact CD1-CD 3.71Å; L208-K585 HydrophobicContact CD2-CB 4.42Å; L208-K585 HydrophobicContact CD2-CD 3.79Å; L208-K585 HydrophobicContact CG-CD 3.84Å
209M88.9Confident93.3Very high4 Ų457.8 Ų57.82%0.0228%0.275CS..Hα-helixtrans-68.4-39177.8-63.5-57.1-66.600111.2I112 S113 I204 S206 D207 K212 L213 Y584I112-M209 HydrophobicContact CD1-CE 4.34Å; I112-M209 HydrophobicContact CG1-CE 4.29Å; S113-M209 VanDerWaalsContact OG-CE 3.22Å; S113-M209 WeakPolarHBondContact OG-CE 3.31Å; I204-M209 HydrophobicContact CG2-CB 3.82Å; S206-M209 WeakPolarHBondContact O-CB 3.34Å; S206-M209 PolarHBondContact O-N 3.34Å; D207-M209 VanDerWaalsContact C-N 3.33Å; D207-M209 PolarHBondContact O-N 3.38Å; M209-K212 PolarHBondContact O-N 3.48Å; M209-L213 PolarHBondContact O-N 3.28Å; M209-Y584 HydrophobicContact CE-CD1 4.43Å; M209-Y584 HydrophobicContact CE-CE1 3.63Å; M209-Y584 HydrophobicContact SD-CD1 4.06Å; M209-Y584 HydrophobicContact SD-CE1 3.84Å
210M93.9Very high93.3Very high32 Ų3254.9 Ų54.916%0.15827%0.265CS..Hα-helixtrans-59-53.6173.3-172.8-172.964.100111.8V195 V196 R199 I204 S206 D207 K212 L213 M214V195-M210 HydrophobicContact CG1-CG 3.55Å; V196-M210 HydrophobicContact CG2-SD 4.4Å; R199-M210 HydrophobicContact CB-CG 4.37Å; R199-M210 HydrophobicContact CB-SD 3.73Å; R199-M210 HydrophobicContact CG-SD 3.8Å; I204-M210 HydrophobicContact CG2-CB 4.25Å; S206-M210 PolarHBondContact O-N 2.64Å; S206-M210 VanDerWaalsContact O-N 3.16Å; D207-M210 WeakPolarHBondContact O-CB 3.33Å; D207-M210 PolarHBondContact O-N 2.82Å; M210-K212 PolarHBondContact O-N 3.26Å; M210-L213 WeakPolarHBondContact O-CB 3.11Å; M210-L213 PolarHBondContact O-N 2.8Å; M210-L213 VanDerWaalsContact O-N 3.11Å; M210-M214 HydrophobicContact CE-CE 4.35Å; M210-M214 HydrophobicContact CG-CE 4.04Å; M210-M214 WeakPolarHBondContact O-CG 3.37Å; M210-M214 PolarHBondContact O-N 3.4Å; M210-M214 HydrophobicContact SD-CE 4.04Å
211V93.9Very high93.3Very high65 Ų6551.8 Ų51.839%0.39425%0.248SC..Hα-helixtrans-58.7-38.1178.8169.40000111.1D207 M214 Q215D207-V211 WeakPolarHBondContact O-CG2 3.38Å; D207-V211 PolarHBondContact O-N 2.67Å; V211-M214 PolarHBondContact O-N 3.44Å; V211-Q215 WeakPolarHBondContact O-CG 3.4Å; V211-Q215 PolarHBondContact O-N 2.83Å
212K89.1Confident93.3Very high28 Ų2852.5 Ų52.512%0.12225%0.254CS..Hα-helixtrans-67.9-38.6178-73.9-73140.9-1760112.5R109 L208 M209 M210 Q215 E216 K585R109-K212 VanDerWaalsContact CD-O 3.27Å; R109-K212 WeakPolarHBondContact CD-O 3.32Å; L208-K212 WeakPolarHBondContact O-CB 3.12Å; L208-K212 WeakPolarHBondContact O-CG 3.39Å; L208-K212 PolarHBondContact O-N 3.42Å; L208-K212 VanDerWaalsContact O-N 3.07Å; M209-K212 PolarHBondContact O-N 3.48Å; M210-K212 PolarHBondContact O-N 3.26Å; K212-Q215 PolarHBondContact O-N 3.35Å; K212-E216 PolarHBondContact O-N 3.2Å; K212-K585 HydrophobicContact CD-CD 4.14Å; K212-K585 HydrophobicContact CD-CG 4.41Å; K212-K585 HydrophobicContact CG-CD 4.16Å; K212-K585 HydrophobicContact CG-CG 4.49Å
213L93.3Very high93.3Very high0 Ų046.3 Ų46.30%023%0.229CC..Hα-helixtrans-64.5-44.9174.1-165.858.1000110.3M106 R109 A110 I114 L128 V195 I204 M209 M210 Q215 E216 I217M106-L213 HydrophobicContact CE-CD1 3.62Å; M106-L213 HydrophobicContact CE-CG 4.17Å; M106-L213 HydrophobicContact SD-CD1 3.87Å; R109-L213 HydrophobicContact CB-CD1 4.31Å; R109-L213 HydrophobicContact CG-CD1 4.22Å; A110-L213 HydrophobicContact CB-CD1 4.12Å; I114-L213 HydrophobicContact CD1-CD2 4.04Å; I114-L213 HydrophobicContact CG1-CD2 4.16Å; L128-L213 HydrophobicContact CD2-CD1 4.18Å; L128-L213 HydrophobicContact CD2-CD2 3.82Å; L128-L213 HydrophobicContact CD2-CG 4.23Å; V195-L213 HydrophobicContact CB-CD2 4.38Å; V195-L213 HydrophobicContact CG1-CB 4.4Å; V195-L213 HydrophobicContact CG1-CD2 4.05Å; V195-L213 HydrophobicContact CG1-CG 4.48Å; V195-L213 HydrophobicContact CG2-CD2 3.45Å; V195-L213 VanDerWaalsContact CG2-CD2 3.45Å; V195-L213 HydrophobicContact CG2-CG 3.88Å; I204-L213 HydrophobicContact CD1-CD2 4.3Å; M209-L213 PolarHBondContact O-N 3.28Å; M210-L213 WeakPolarHBondContact O-CB 3.11Å; M210-L213 PolarHBondContact O-N 2.8Å; M210-L213 VanDerWaalsContact O-N 3.11Å; L213-Q215 VanDerWaalsContact C-N 3.3Å; L213-Q215 PolarHBondContact O-N 3.18Å; L213-E216 PolarHBondContact O-N 2.8Å; L213-E216 VanDerWaalsContact O-N 3.13Å; L213-I217 WeakPolarHBondContact O-CG1 3.26Å; L213-I217 PolarHBondContact O-N 3.29Å; L213-I217 VanDerWaalsContact O-N 3.09Å
214M94.8Very high93.3Very high50 Ų5043.6 Ų43.625%0.24622%0.219CC..Hα-helixtrans-57.9-39.6173.2-69.2-178.7174.500112.7V195 V196 M210 V211 E216 I217 M218V195-M214 HydrophobicContact CG1-CE 4.32Å; V195-M214 HydrophobicContact CG1-CG 4.28Å; V196-M214 HydrophobicContact CG2-CE 3.43Å; V196-M214 VanDerWaalsContact CG2-CE 3.43Å; M210-M214 HydrophobicContact CE-CE 4.35Å; M210-M214 HydrophobicContact CG-CE 4.04Å; M210-M214 WeakPolarHBondContact O-CG 3.37Å; M210-M214 PolarHBondContact O-N 3.4Å; M210-M214 HydrophobicContact SD-CE 4.04Å; V211-M214 PolarHBondContact O-N 3.44Å; M214-E216 VanDerWaalsContact C-N 3.35Å; M214-E216 PolarHBondContact O-N 2.9Å; M214-I217 WeakPolarHBondContact O-CB 3.48Å; M214-I217 PolarHBondContact O-N 2.86Å; M214-M218 WeakPolarHBondContact O-CG 3.43Å; M214-M218 PolarHBondContact O-N 3.42Å
215Q94.6Very high93.3Very high88 Ų8844.8 Ų44.841%0.41123%0.229SC..Hα-helixtrans-62.9-37.6176.3-76.7178.3-9.100113V211 K212 L213 M218 K219V211-Q215 WeakPolarHBondContact O-CG 3.4Å; V211-Q215 PolarHBondContact O-N 2.83Å; K212-Q215 PolarHBondContact O-N 3.35Å; L213-Q215 VanDerWaalsContact C-N 3.3Å; L213-Q215 PolarHBondContact O-N 3.18Å; Q215-M218 PolarHBondContact O-N 3.48Å; Q215-K219 WeakPolarHBondContact O-CG 3.27Å; Q215-K219 PolarHBondContact O-N 3.26Å
216E93.1Very high93.6Very high10 Ų1043.6 Ų43.65%0.04722%0.224CC..Hα-helixtrans-69.5-37.4174.5-64.9-60.3147.900111.8M106 R109 K212 L213 M214 M218 K219 V220M106-E216 HydrophobicContact CB-CB 4.07Å; M106-E216 HydrophobicContact CG-CB 4.3Å; M106-E216 HydrophobicContact SD-CB 3.33Å; M106-E216 WeakPolarHBondContact SD-CB 3.29Å; M106-E216 HydrophobicContact SD-CG 4.43Å; R109-E216 HydrophobicContact CB-CG 4.31Å; R109-E216 VanDerWaalsContact CD-CG 3.49Å; R109-E216 IonicContact CZ-OE1 3.09Å; R109-E216 IonicContact NE-OE1 2.95Å; R109-E216 PolarHBondContact NE-OE1 3.41Å; R109-E216 IonicContact NH2-OE1 3.98Å; R109-E216 PolarHBondContact NH2-OE1 3.34Å; K212-E216 PolarHBondContact O-N 3.2Å; L213-E216 PolarHBondContact O-N 2.8Å; L213-E216 VanDerWaalsContact O-N 3.13Å; M214-E216 VanDerWaalsContact C-N 3.35Å; M214-E216 PolarHBondContact O-N 2.9Å; E216-M218 VanDerWaalsContact C-N 3.28Å; E216-M218 PolarHBondContact O-N 3.1Å; E216-K219 VanDerWaalsContact CD-NZ 3.35Å; E216-K219 WeakPolarHBondContact O-CB 3.17Å; E216-K219 PolarHBondContact O-N 2.98Å; E216-K219 IonicContact OE1-NZ 2.66Å; E216-K219 PolarHBondContact OE1-NZ 3.47Å; E216-K219 WeakPolarHBondContact OE2-CD 3.25Å; E216-K219 IonicContact OE2-NZ 3.7Å; E216-K219 PolarHBondContact OE2-NZ 3.44Å; E216-V220 PolarHBondContact O-N 2.88Å; E216-V220 VanDerWaalsContact O-N 3.14Å
217I96.5Very high93.7Very high0 Ų042.8 Ų42.80%022%0.219CC..Hα-helixtrans-57.9-44.5170.7-58.7175.8000110M106 L128 I132 L188 A191 V195 L213 M214 K219 V220 R221M106-I217 HydrophobicContact CE-CD1 4.12Å; M106-I217 HydrophobicContact CE-CG1 3.47Å; M106-I217 VanDerWaalsContact CE-CG1 3.47Å; M106-I217 HydrophobicContact SD-CG1 3.99Å; L128-I217 HydrophobicContact CD1-CD1 4.36Å; I132-I217 HydrophobicContact CD1-CB 4.4Å; I132-I217 HydrophobicContact CD1-CG1 3.93Å; I132-I217 HydrophobicContact CD1-CG2 4.08Å; L188-I217 HydrophobicContact CB-CG2 4.19Å; L188-I217 HydrophobicContact CD2-CG2 4.14Å; A191-I217 HydrophobicContact CB-CD1 4.07Å; V195-I217 HydrophobicContact CG2-CD1 4.06Å; L213-I217 WeakPolarHBondContact O-CG1 3.26Å; L213-I217 PolarHBondContact O-N 3.29Å; L213-I217 VanDerWaalsContact O-N 3.09Å; M214-I217 WeakPolarHBondContact O-CB 3.48Å; M214-I217 PolarHBondContact O-N 2.86Å; I217-K219 VanDerWaalsContact C-N 3.34Å; I217-K219 PolarHBondContact O-N 3.02Å; I217-V220 PolarHBondContact O-N 3.25Å; I217-R221 PolarHBondContact O-N 3.06Å
218M95.9Very high93.7Very high65 Ų6540.1 Ų40.132%0.3220%0.204SC..Hα-helixtrans-67.1-31.4178.7-69.1-56.9101.200113.4M214 Q215 E216 R221 N222M214-M218 WeakPolarHBondContact O-CG 3.43Å; M214-M218 PolarHBondContact O-N 3.42Å; Q215-M218 PolarHBondContact O-N 3.48Å; E216-M218 VanDerWaalsContact C-N 3.28Å; E216-M218 PolarHBondContact O-N 3.1Å; M218-R221 HydrophobicContact CE-CB 4.49Å; M218-R221 WeakPolarHBondContact O-CB 3.23Å; M218-R221 PolarHBondContact O-N 3.27Å; M218-N222 VanDerWaalsContact O-CG 3.23Å; M218-N222 PolarHBondContact O-N 3.09Å; M218-N222 PolarHBondContact O-ND2 3.22Å
219K95.1Very high93.8Very high112 Ų11239.8 Ų39.849%0.48721%0.209SC..Hα-helixtrans-63.4-44.9171.6-72.3173.4-173.5172.90111.2Q215 E216 I217 R221 N222 S223Q215-K219 WeakPolarHBondContact O-CG 3.27Å; Q215-K219 PolarHBondContact O-N 3.26Å; E216-K219 VanDerWaalsContact CD-NZ 3.35Å; E216-K219 WeakPolarHBondContact O-CB 3.17Å; E216-K219 PolarHBondContact O-N 2.98Å; E216-K219 IonicContact OE1-NZ 2.66Å; E216-K219 PolarHBondContact OE1-NZ 3.47Å; E216-K219 WeakPolarHBondContact OE2-CD 3.25Å; E216-K219 IonicContact OE2-NZ 3.7Å; E216-K219 PolarHBondContact OE2-NZ 3.44Å; I217-K219 VanDerWaalsContact C-N 3.34Å; I217-K219 PolarHBondContact O-N 3.02Å; K219-R221 VanDerWaalsContact C-N 3.33Å; K219-R221 PolarHBondContact O-N 3.42Å; K219-N222 PolarHBondContact O-N 3.4Å; K219-S223 PolarHBondContact O-N 3.22Å; K219-S223 PolarHBondContact O-OG 3.02Å
220V95.8Very high93.8Very high9 Ų942.7 Ų42.76%0.05522%0.22CC..Hα-helixtrans-59.9-46.5174.5177.50000110.1I132 E216 I217 N222 S223 V224I132-V220 HydrophobicContact CG2-CG1 4.27Å; I132-V220 HydrophobicContact CG2-CG2 4.18Å; E216-V220 PolarHBondContact O-N 2.88Å; E216-V220 VanDerWaalsContact O-N 3.14Å; I217-V220 PolarHBondContact O-N 3.25Å; V220-N222 VanDerWaalsContact C-N 3.31Å; V220-N222 PolarHBondContact O-N 3.45Å; V220-S223 WeakPolarHBondContact O-CB 3.12Å; V220-S223 PolarHBondContact O-N 3.17Å; V220-S223 VanDerWaalsContact O-N 3.17Å; V220-V224 HydrophobicContact CG1-CG1 4.42Å; V220-V224 WeakPolarHBondContact O-CG2 3.22Å; V220-V224 PolarHBondContact O-N 3.26Å
221R96.1Very high93.4Very high104 Ų10445.5 Ų45.539%0.39224%0.236SC..Hα-helixtrans-53.2-47.7175.3-169-89.2-68.4179.6-4111.9L188 I217 M218 K219 V224 A225L188-R221 HydrophobicContact CD1-CB 3.66Å; L188-R221 HydrophobicContact CD1-CG 3.99Å; I217-R221 PolarHBondContact O-N 3.06Å; M218-R221 HydrophobicContact CE-CB 4.49Å; M218-R221 WeakPolarHBondContact O-CB 3.23Å; M218-R221 PolarHBondContact O-N 3.27Å; K219-R221 VanDerWaalsContact C-N 3.33Å; K219-R221 PolarHBondContact O-N 3.42Å; R221-V224 VanDerWaalsContact O-CG2 3.32Å; R221-V224 WeakPolarHBondContact O-CG2 3.32Å; R221-V224 PolarHBondContact O-N 2.89Å; R221-A225 WeakPolarHBondContact O-CB 3.31Å; R221-A225 PolarHBondContact O-N 3.35Å
222N95.6Very high93.1Very high77 Ų7752.2 Ų52.241%0.41225%0.254SS..Hα-helixtrans-64.9-41.5179.9-70.5-18.2000112.1M218 K219 V220 T226M218-N222 VanDerWaalsContact O-CG 3.23Å; M218-N222 PolarHBondContact O-N 3.09Å; M218-N222 PolarHBondContact O-ND2 3.22Å; K219-N222 PolarHBondContact O-N 3.4Å; V220-N222 VanDerWaalsContact C-N 3.31Å; V220-N222 PolarHBondContact O-N 3.45Å; N222-T226 WeakPolarHBondContact O-CB 3.08Å; N222-T226 PolarHBondContact O-N 2.82Å; N222-T226 PolarHBondContact O-OG1 3.05Å
223S95.4Very high93.1Very high36 Ų3656 Ų5625%0.25227%0.274SS..Hα-helixtrans-59-52.7175.1-75.40000111.6S99 K219 V220 T226 L227S99-S223 WeakPolarHBondContact O-CB 3.27Å; K219-S223 PolarHBondContact O-N 3.22Å; K219-S223 PolarHBondContact O-OG 3.02Å; V220-S223 WeakPolarHBondContact O-CB 3.12Å; V220-S223 PolarHBondContact O-N 3.17Å; V220-S223 VanDerWaalsContact O-N 3.17Å; S223-T226 WeakPolarHBondContact O-CB 3.38Å; S223-T226 PolarHBondContact O-N 3.29Å; S223-L227 PolarHBondContact O-N 2.84Å; S223-L227 VanDerWaalsContact O-N 3.12Å
224V95.1Very high92.6Very high0 Ų059.7 Ų59.70%030%0.3CS..Hα-helixtrans-69-35.9-179.3-59.60000112.6P101 V139 Y184 V220 R221 T226 L227 I228P101-V224 HydrophobicContact CB-CG1 4.36Å; P101-V224 HydrophobicContact CG-CG1 4.32Å; V139-V224 HydrophobicContact CB-CB 4.35Å; V139-V224 HydrophobicContact CG1-CB 4.21Å; V139-V224 HydrophobicContact CG2-CB 4.11Å; V139-V224 HydrophobicContact CG2-CG2 4.47Å; Y184-V224 HydrophobicContact CD2-CG2 4.24Å; Y184-V224 HydrophobicContact CE2-CG2 3.82Å; V220-V224 HydrophobicContact CG1-CG1 4.42Å; V220-V224 WeakPolarHBondContact O-CG2 3.22Å; V220-V224 PolarHBondContact O-N 3.26Å; R221-V224 VanDerWaalsContact O-CG2 3.32Å; R221-V224 WeakPolarHBondContact O-CG2 3.32Å; R221-V224 PolarHBondContact O-N 2.89Å; V224-T226 VanDerWaalsContact C-N 3.27Å; V224-T226 PolarHBondContact O-N 2.82Å; V224-L227 WeakPolarHBondContact O-CB 3.49Å; V224-L227 PolarHBondContact O-N 3.05Å; V224-I228 WeakPolarHBondContact O-CG1 3.25Å; V224-I228 PolarHBondContact O-N 3.37Å
225A93.9Very high92.2Very high26 Ų2658.7 Ų58.722%0.21530%0.296CS..Hα-helixtrans-62.7-36.6173.500000111.6R221 I228 A229R221-A225 WeakPolarHBondContact O-CB 3.31Å; R221-A225 PolarHBondContact O-N 3.35Å; A225-I228 PolarHBondContact O-N 3.48Å; A225-A229 VanDerWaalsContact O-CB 3.3Å; A225-A229 WeakPolarHBondContact O-CB 3.32Å; A225-A229 PolarHBondContact O-N 2.99Å
226T94.1Very high92Very high52 Ų5258.1 Ų58.132%0.31930%0.3SS..Hα-helixtrans-66.4-39.6175.3-54.80000111.3S99 N222 S223 V224 A229 Y230S99-T226 WeakPolarHBondContact OG-CG2 3.34Å; N222-T226 WeakPolarHBondContact O-CB 3.08Å; N222-T226 PolarHBondContact O-N 2.82Å; N222-T226 PolarHBondContact O-OG1 3.05Å; S223-T226 WeakPolarHBondContact O-CB 3.38Å; S223-T226 PolarHBondContact O-N 3.29Å; V224-T226 VanDerWaalsContact C-N 3.27Å; V224-T226 PolarHBondContact O-N 2.82Å; T226-A229 PolarHBondContact O-N 3.33Å; T226-Y230 HydrophobicContact CG2-CD2 3.8Å; T226-Y230 HydrophobicContact CG2-CE2 3.59Å; T226-Y230 VanDerWaalsContact O-CD2 3.27Å; T226-Y230 WeakPolarHBondContact O-CD2 3.2Å; T226-Y230 PolarHBondContact O-N 3.22Å
227L91.8Very high91.8Very high0 Ų063.1 Ų63.10%033%0.326CS..Hα-helixtrans-62.9-44.4174.1-67.5177.8000111.9L100 L140 S223 V224 Y230 N231 F298L100-L227 HydrophobicContact CD2-CD1 4.48Å; L140-L227 HydrophobicContact CD2-CD1 4.29Å; S223-L227 PolarHBondContact O-N 2.84Å; S223-L227 VanDerWaalsContact O-N 3.12Å; V224-L227 WeakPolarHBondContact O-CB 3.49Å; V224-L227 PolarHBondContact O-N 3.05Å; L227-Y230 PolarHBondContact O-N 3.38Å; L227-N231 WeakPolarHBondContact O-CB 3.37Å; L227-N231 PolarHBondContact O-N 3.28Å; L227-F298 HydrophobicContact CD2-CZ 3.77Å
228I91.1Very high91.6Very high34 Ų3467.5 Ų67.517%0.17435%0.353CS..Hα-helixtrans-61.3-46.4174.9-64.8163.4000110.1V139 Y182 Y184 V224 A225 Y230 N231 W232V139-I228 HydrophobicContact CG1-CD1 4.15Å; V139-I228 HydrophobicContact CG1-CG1 3.7Å; V139-I228 HydrophobicContact CG2-CD1 3.88Å; V139-I228 HydrophobicContact CG2-CG1 4.35Å; Y182-I228 HydrophobicContact CD1-CD1 4.31Å; Y182-I228 HydrophobicContact CE1-CD1 3.77Å; Y182-I228 HydrophobicContact CE1-CG1 4.15Å; Y182-I228 HydrophobicContact CE1-CG2 4.49Å; Y184-I228 HydrophobicContact CD1-CD1 3.64Å; Y184-I228 HydrophobicContact CD2-CD1 3.69Å; Y184-I228 HydrophobicContact CE1-CD1 3.57Å; Y184-I228 HydrophobicContact CE2-CD1 3.63Å; Y184-I228 HydrophobicContact CG-CD1 3.7Å; V224-I228 WeakPolarHBondContact O-CG1 3.25Å; V224-I228 PolarHBondContact O-N 3.37Å; A225-I228 PolarHBondContact O-N 3.48Å; I228-Y230 VanDerWaalsContact C-N 3.33Å; I228-Y230 PolarHBondContact O-N 3.25Å; I228-N231 PolarHBondContact O-N 3.15Å; I228-N231 VanDerWaalsContact O-N 3.12Å; I228-W232 WeakPolarHBondContact O-CB 3.48Å; I228-W232 PolarHBondContact O-N 2.89Å
229A91.7Very high91.4Very high44 Ų4467.9 Ų67.936%0.36435%0.351SS..Hα-helixtrans-61.7-40.5-179.800000112A225 T226 I233A225-A229 VanDerWaalsContact O-CB 3.3Å; A225-A229 WeakPolarHBondContact O-CB 3.32Å; A225-A229 PolarHBondContact O-N 2.99Å; T226-A229 PolarHBondContact O-N 3.33Å; A229-I233 WeakPolarHBondContact O-CB 3.14Å; A229-I233 PolarHBondContact O-N 3.27Å
230Y89.3Confident91.1Very high64 Ų6464 Ų6425%0.25134%0.337SS..Hα-helixtrans-64.7-46.2171.6-80.2-55.8000111R92 S95 N96 T226 L227 I228 W232 I233R92-Y230 HydrophobicContact CG-CD1 4.2Å; R92-Y230 HydrophobicContact CG-CE1 4.18Å; R92-Y230 VanDerWaalsContact NH2-C 3.33Å; R92-Y230 PolarHBondContact NH2-O 2.88Å; S95-Y230 VanDerWaalsContact CB-OH 3.25Å; S95-Y230 WeakPolarHBondContact CB-OH 3.24Å; N96-Y230 WeakPolarHBondContact OD1-CB 3.43Å; T226-Y230 HydrophobicContact CG2-CD2 3.8Å; T226-Y230 HydrophobicContact CG2-CE2 3.59Å; T226-Y230 VanDerWaalsContact O-CD2 3.27Å; T226-Y230 WeakPolarHBondContact O-CD2 3.2Å; T226-Y230 PolarHBondContact O-N 3.22Å; L227-Y230 PolarHBondContact O-N 3.38Å; I228-Y230 VanDerWaalsContact C-N 3.33Å; I228-Y230 PolarHBondContact O-N 3.25Å; Y230-W232 VanDerWaalsContact C-N 3.3Å; Y230-W232 PolarHBondContact O-N 2.61Å; Y230-I233 CarbonylContact O-C 3.6Å; Y230-I233 VanDerWaalsContact O-C 3.31Å; Y230-I233 VanDerWaalsContact O-O 3.04Å
231N85.1Confident91Very high92 Ų9268.1 Ų68.149%0.49236%0.356SS..Hα-helixtrans-61.7-38.7178.6-170.2-94000112.7V143 L227 I228V143-N231 HydrophobicContact CB-CB 4.33Å; V143-N231 HydrophobicContact CG1-CB 3.78Å; L227-N231 WeakPolarHBondContact O-CB 3.37Å; L227-N231 PolarHBondContact O-N 3.28Å; I228-N231 PolarHBondContact O-N 3.15Å; I228-N231 VanDerWaalsContact O-N 3.12Å
232W87.4Confident90.9Very high206 Ų20666.9 Ų66.978%0.7836%0.359SS*.Hα-helixtrans-71.7-47.1178.5-178.633.7000112.8I228 Y230 S234I228-W232 WeakPolarHBondContact O-CB 3.48Å; I228-W232 PolarHBondContact O-N 2.89Å; Y230-W232 VanDerWaalsContact C-N 3.3Å; Y230-W232 PolarHBondContact O-N 2.61Å; W232-S234 PolarHBondContact O-N 3.07Å
233I88.9Confident90.8Very high106 Ų10663.2 Ų63.254%0.54434%0.34SS..SBendtrans-100.984.1179.4-52.5174000107.8R92 A229 Y230R92-I233 VanDerWaalsContact CZ-O 3.31Å; R92-I233 PolarHBondContact NH1-O 3.35Å; R92-I233 PolarHBondContact NH2-O 3.14Å; A229-I233 WeakPolarHBondContact O-CB 3.14Å; A229-I233 PolarHBondContact O-N 3.27Å; Y230-I233 CarbonylContact O-C 3.6Å; Y230-I233 VanDerWaalsContact O-C 3.31Å; Y230-I233 VanDerWaalsContact O-O 3.04Å
234S83.8Confident90.7Very high78 Ų7863.7 Ų63.755%0.54534%0.341SS..PPolyproline II helixtrans-70.7166.7173.558.90000111.8W232W232-S234 PolarHBondContact O-N 3.07Å
235L85.8Confident90.7Very high30 Ų3068.7 Ų68.716%0.15737%0.367CS..SBendtrans-59.7133.6166.2-76173.1000108.1F85 V89 L237 I295F85-L235 HydrophobicContact CE2-CD1 4.49Å; V89-L235 HydrophobicContact CB-CD1 4.4Å; V89-L235 HydrophobicContact CG2-CD1 3.6Å; L235-L237 PolarHBondContact O-N 2.94Å; L235-I295 HydrophobicContact CB-CD1 4.44Å; L235-I295 HydrophobicContact CD1-CD1 4.13Å; L235-I295 HydrophobicContact CD1-CG1 4.2Å
236P90Very high90.7Very high76 Ų7668.1 Ų68.149%0.49436%0.362SS..PPolyproline II helixtrans-51127.7-176.7-29.235.1000111.4V238 Y239 T240P236-V238 HydrophobicContact CB-CG1 4.04Å; P236-V238 PolarHBondContact O-N 3.34Å; P236-Y239 WeakPolarHBondContact O-CB 3.48Å; P236-Y239 PolarHBondContact O-N 3.33Å; P236-T240 PolarHBondContact O-N 2.83Å
237L88.9Confident90.6Very high115 Ų11565.6 Ų65.660%0.60235%0.347SS*.Hα-helixtrans-54.6-39.7-177.8178.161000111.2L235 Y239 T240 Q241L235-L237 PolarHBondContact O-N 2.94Å; L237-Y239 PolarHBondContact O-N 2.94Å; L237-T240 PolarHBondContact O-N 3.33Å; L237-T240 VanDerWaalsContact O-N 3.16Å; L237-Q241 HydrophobicContact CD1-CG 4.1Å; L237-Q241 HydrophobicContact CG-CG 4.04Å; L237-Q241 WeakPolarHBondContact O-CB 3.44Å; L237-Q241 WeakPolarHBondContact O-CG 3.2Å; L237-Q241 PolarHBondContact O-N 3.24Å
238V93.1Very high90.8Very high91 Ų9169.7 Ų69.755%0.55237%0.366SS*.Hα-helixtrans-56.2-35.6176.266.70000112.7P236 Q241 V242P236-V238 HydrophobicContact CB-CG1 4.04Å; P236-V238 PolarHBondContact O-N 3.34Å; V238-Q241 PolarHBondContact O-N 3.5Å; V238-V242 HydrophobicContact CG2-CG2 4.23Å; V238-V242 WeakPolarHBondContact O-CB 3.28Å; V238-V242 WeakPolarHBondContact O-CG2 3.4Å; V238-V242 PolarHBondContact O-N 3.41Å
239Y91.1Very high90.9Very high73 Ų7370.9 Ų70.929%0.28638%0.377SS..Hα-helixtrans-69.6-47.2178.7-168-174.3000110.4F85 P236 L237 Q241 V242 V243F85-Y239 HydrophobicContact CB-CE2 4.22Å; F85-Y239 HydrophobicContact CD2-CD1 4.24Å; F85-Y239 HydrophobicContact CD2-CD2 4.19Å; F85-Y239 HydrophobicContact CD2-CE1 4.15Å; F85-Y239 HydrophobicContact CD2-CE2 4.08Å; F85-Y239 HydrophobicContact CD2-CG 4.26Å; F85-Y239 PolarHBondContact N-OH 2.92Å; P236-Y239 WeakPolarHBondContact O-CB 3.48Å; P236-Y239 PolarHBondContact O-N 3.33Å; L237-Y239 PolarHBondContact O-N 2.94Å; Y239-Q241 VanDerWaalsContact C-N 3.3Å; Y239-Q241 PolarHBondContact O-N 3.46Å; Y239-V242 PolarHBondContact O-N 3.29Å; Y239-V243 HydrophobicContact CD2-CG2 3.7Å; Y239-V243 HydrophobicContact CE2-CG2 3.66Å; Y239-V243 WeakPolarHBondContact O-CG2 3.15Å; Y239-V243 PolarHBondContact O-N 3.13Å
240T90Very high90.9Very high32 Ų3269.4 Ų69.420%0.19636%0.362CS..Hα-helixtrans-58.9-43.2174.1-52.30000111.1F85 P236 L237 T244F85-T240 HydrophobicContact CZ-CG2 4.21Å; P236-T240 PolarHBondContact O-N 2.83Å; L237-T240 PolarHBondContact O-N 3.33Å; L237-T240 VanDerWaalsContact O-N 3.16Å; T240-T244 WeakPolarHBondContact O-CB 3.49Å; T240-T244 PolarHBondContact O-N 2.95Å; T240-T244 PolarHBondContact O-OG1 3.2Å
241Q93.6Very high91.2Very high94 Ų9466.6 Ų66.644%0.43935%0.351SS..Hα-helixtrans-63.5-48.5177.6-75.2174.2-31.300112L237 V238 Y239 V243 T244 I245L237-Q241 HydrophobicContact CD1-CG 4.1Å; L237-Q241 HydrophobicContact CG-CG 4.04Å; L237-Q241 WeakPolarHBondContact O-CB 3.44Å; L237-Q241 WeakPolarHBondContact O-CG 3.2Å; L237-Q241 PolarHBondContact O-N 3.24Å; V238-Q241 PolarHBondContact O-N 3.5Å; Y239-Q241 VanDerWaalsContact C-N 3.3Å; Y239-Q241 PolarHBondContact O-N 3.46Å; Q241-V243 VanDerWaalsContact C-N 3.34Å; Q241-V243 PolarHBondContact O-N 2.8Å; Q241-T244 PolarHBondContact O-N 2.89Å; Q241-I245 HydrophobicContact CB-CD1 4.49Å; Q241-I245 VanDerWaalsContact O-CB 3.3Å; Q241-I245 WeakPolarHBondContact O-CB 3.47Å; Q241-I245 WeakPolarHBondContact O-CG1 3.23Å; Q241-I245 PolarHBondContact O-N 3.3Å
242V93.6Very high91.7Very high78 Ų7866.6 Ų66.647%0.47336%0.355SS..Hα-helixtrans-59.2-45.9179.3166.10000110.9V238 Y239 A246V238-V242 HydrophobicContact CG2-CG2 4.23Å; V238-V242 WeakPolarHBondContact O-CB 3.28Å; V238-V242 WeakPolarHBondContact O-CG2 3.4Å; V238-V242 PolarHBondContact O-N 3.41Å; Y239-V242 PolarHBondContact O-N 3.29Å; V242-A246 VanDerWaalsContact O-CB 3.23Å; V242-A246 WeakPolarHBondContact O-CB 3.36Å; V242-A246 PolarHBondContact O-N 3.23Å
243V93.5Very high92Very high0 Ų058 Ų580%033%0.325CS..Hα-helixtrans-65.4-44.4178.7179.50000110.5I81 M82 F85 Y239 Q241 A246 T247 L288I81-V243 HydrophobicContact CG2-CB 4.29Å; I81-V243 HydrophobicContact CG2-CG1 4.32Å; I81-V243 HydrophobicContact CG2-CG2 3.69Å; M82-V243 HydrophobicContact CE-CG1 4.46Å; M82-V243 HydrophobicContact SD-CG1 3.28Å; M82-V243 WeakPolarHBondContact SD-CG1 3.48Å; F85-V243 HydrophobicContact CB-CG1 4.25Å; F85-V243 HydrophobicContact CB-CG2 3.81Å; F85-V243 HydrophobicContact CD1-CB 4.28Å; F85-V243 HydrophobicContact CD1-CG1 3.75Å; F85-V243 HydrophobicContact CD1-CG2 4.25Å; F85-V243 HydrophobicContact CD2-CG2 3.97Å; F85-V243 HydrophobicContact CE1-CG1 4.3Å; F85-V243 HydrophobicContact CG-CB 4.29Å; F85-V243 HydrophobicContact CG-CG1 4.07Å; F85-V243 HydrophobicContact CG-CG2 3.76Å; Y239-V243 HydrophobicContact CD2-CG2 3.7Å; Y239-V243 HydrophobicContact CE2-CG2 3.66Å; Y239-V243 WeakPolarHBondContact O-CG2 3.15Å; Y239-V243 PolarHBondContact O-N 3.13Å; Q241-V243 VanDerWaalsContact C-N 3.34Å; Q241-V243 PolarHBondContact O-N 2.8Å; V243-A246 PolarHBondContact O-N 3.44Å; V243-T247 PolarHBondContact O-N 3.45Å; V243-T247 PolarHBondContact O-OG1 3.15Å; V243-L288 HydrophobicContact CG1-CD1 4.08Å
244T93.3Very high92.2Very high47 Ų4753 Ų5329%0.28830%0.299SS..Hα-helixtrans-63-47.5178.6-58.70000111.4T240 Q241 T247 H248T240-T244 WeakPolarHBondContact O-CB 3.49Å; T240-T244 PolarHBondContact O-N 2.95Å; T240-T244 PolarHBondContact O-OG1 3.2Å; Q241-T244 PolarHBondContact O-N 2.89Å; T244-T247 PolarHBondContact O-N 3.47Å; T244-H248 WeakPolarHBondContact CG2-ND1 3.45Å; T244-H248 WeakPolarHBondContact O-CB 3.41Å; T244-H248 PolarHBondContact O-N 3.04Å; T244-H248 PolarHBondContact O-ND1 3.21Å
245I94.2Very high92.6Very high105 Ų10550 Ų5054%0.53828%0.277SS..Hα-helixtrans-62.5-43.4177.3-69.8166.6000110Q241 T247 H248 S249Q241-I245 HydrophobicContact CB-CD1 4.49Å; Q241-I245 VanDerWaalsContact O-CB 3.3Å; Q241-I245 WeakPolarHBondContact O-CB 3.47Å; Q241-I245 WeakPolarHBondContact O-CG1 3.23Å; Q241-I245 PolarHBondContact O-N 3.3Å; I245-T247 PolarHBondContact O-N 2.99Å; I245-H248 PolarHBondContact O-N 2.84Å; I245-S249 WeakPolarHBondContact O-CB 3.5Å; I245-S249 PolarHBondContact O-N 3.19Å; I245-S249 PolarHBondContact O-OG 3.16Å
246A93.7Very high93Very high13 Ų1350.6 Ų50.611%0.10728%0.28CS..Hα-helixtrans-59.6-48.6177.900000111.5L78 V242 V243 F250L78-A246 HydrophobicContact CD1-CB 3.97Å; V242-A246 VanDerWaalsContact O-CB 3.23Å; V242-A246 WeakPolarHBondContact O-CB 3.36Å; V242-A246 PolarHBondContact O-N 3.23Å; V243-A246 PolarHBondContact O-N 3.44Å; A246-F250 VanDerWaalsContact O-CB 3.23Å; A246-F250 WeakPolarHBondContact O-CB 3.03Å; A246-F250 PolarHBondContact O-N 3.16Å
247T93.4Very high92.9Very high0 Ų047 Ų470%026%0.256CS..Hα-helixtrans-64.9-47.4178.6-52.80000112.1M82 V243 T244 I245 F250 F251 M285 L288M82-T247 PolarHBondContact SD-OG1 3.45Å; M82-T247 VanDerWaalsContact SD-OG1 3.36Å; V243-T247 PolarHBondContact O-N 3.45Å; V243-T247 PolarHBondContact O-OG1 3.15Å; T244-T247 PolarHBondContact O-N 3.47Å; I245-T247 PolarHBondContact O-N 2.99Å; T247-F250 WeakPolarHBondContact O-CB 3.46Å; T247-F250 PolarHBondContact O-N 3.27Å; T247-F251 HydrophobicContact CG2-CD2 4.07Å; T247-F251 HydrophobicContact CG2-CE2 3.91Å; T247-F251 WeakPolarHBondContact O-CD2 3.23Å; T247-F251 PolarHBondContact O-N 3.24Å; T247-F251 VanDerWaalsContact O-N 3.16Å; T247-M285 HydrophobicContact CG2-CG 4.43Å; T247-M285 HydrophobicContact CG2-SD 3.57Å; T247-M285 VanDerWaalsContact CG2-SD 3.57Å; T247-L288 HydrophobicContact CG2-CD2 4.04Å
248H94.5Very high92.9Very high86 Ų8642.9 Ų42.940%0.39823%0.233SC..Hα-helixtrans-69.2-41.7-178.2-72.977.5000111.7T244 I245 F250 F251 V252T244-H248 WeakPolarHBondContact CG2-ND1 3.45Å; T244-H248 WeakPolarHBondContact O-CB 3.41Å; T244-H248 PolarHBondContact O-N 3.04Å; T244-H248 PolarHBondContact O-ND1 3.21Å; I245-H248 PolarHBondContact O-N 2.84Å; H248-F250 VanDerWaalsContact C-N 3.31Å; H248-F250 PolarHBondContact O-N 3.26Å; H248-F251 PolarHBondContact O-N 2.9Å; H248-F251 VanDerWaalsContact O-N 3.14Å; H248-V252 WeakPolarHBondContact O-CB 3.13Å; H248-V252 VanDerWaalsContact O-CG2 3.31Å; H248-V252 WeakPolarHBondContact O-CG2 3.39Å; H248-V252 PolarHBondContact O-N 2.85Å
249S93.2Very high92.7Very high58 Ų5838.6 Ų38.641%0.40621%0.207SC..Hα-helixtrans-62.3-41.6176.6-56.10000110.9I245 F251 V252 T253I245-S249 WeakPolarHBondContact O-CB 3.5Å; I245-S249 PolarHBondContact O-N 3.19Å; I245-S249 PolarHBondContact O-OG 3.16Å; S249-F251 VanDerWaalsContact C-N 3.29Å; S249-F251 PolarHBondContact O-N 3.18Å; S249-V252 PolarHBondContact O-N 3.18Å; S249-T253 WeakPolarHBondContact O-CG2 3.4Å; S249-T253 PolarHBondContact O-N 3.4Å; S249-T253 PolarHBondContact O-OG1 2.79Å
250F93.7Very high92.3Very high13 Ų1335.2 Ų35.26%0.05719%0.194CC..Hα-helixtrans-56.4-42.1173.7177.4-95.7000112.2N73 L76 L78 A246 T247 H248 T253 N254 Y284N73-F250 HydrophobicContact CB-CD2 4.21Å; N73-F250 HydrophobicContact CB-CE2 4.03Å; L76-F250 HydrophobicContact CD2-CB 3.92Å; L76-F250 HydrophobicContact CD2-CD2 4.09Å; L76-F250 HydrophobicContact CD2-CG 4.44Å; L78-F250 HydrophobicContact CD2-CB 4Å; L78-F250 HydrophobicContact CD2-CD1 3.8Å; L78-F250 HydrophobicContact CD2-CD2 4.3Å; L78-F250 HydrophobicContact CD2-CE1 4.34Å; L78-F250 HydrophobicContact CD2-CG 3.77Å; A246-F250 VanDerWaalsContact O-CB 3.23Å; A246-F250 WeakPolarHBondContact O-CB 3.03Å; A246-F250 PolarHBondContact O-N 3.16Å; T247-F250 WeakPolarHBondContact O-CB 3.46Å; T247-F250 PolarHBondContact O-N 3.27Å; H248-F250 VanDerWaalsContact C-N 3.31Å; H248-F250 PolarHBondContact O-N 3.26Å; F250-T253 PolarHBondContact O-OG1 3.11Å; F250-N254 WeakPolarHBondContact CE1-ND2 3.15Å; F250-N254 WeakPolarHBondContact CE2-ND2 3.32Å; F250-N254 VanDerWaalsContact CZ-ND2 3.32Å; F250-N254 WeakPolarHBondContact CZ-ND2 3.34Å; F250-N254 VanDerWaalsContact O-CB 3.31Å; F250-N254 WeakPolarHBondContact O-CB 3.25Å; F250-N254 PolarHBondContact O-N 2.85Å; F250-N254 VanDerWaalsContact O-N 3.07Å; F250-N254 PolarHBondContact O-ND2 3.4Å; F250-Y284 HydrophobicContact CE1-CD2 4.19Å; F250-Y284 HydrophobicContact CE1-CE2 4.29Å; F250-Y284 HydrophobicContact CZ-CE2 4.45Å
251F94.7Very high92Very high6 Ų634.3 Ų34.33%0.02619%0.188CC..Hα-helixtrans-78.1-35.8178.5-76.2-60.4000113.8F39 T247 H248 S249 N254 L255 L277 Q280 F281 Y284 M285F39-F251 HydrophobicContact CD2-CB 4.45Å; F39-F251 HydrophobicContact CE2-CB 3.89Å; F39-F251 AromaticContact CE2-CD1 3.97Å; F39-F251 HydrophobicContact CE2-CD1 3.97Å; F39-F251 HydrophobicContact CE2-CG 4.26Å; F39-F251 HydrophobicContact CZ-CD1 4.09Å; T247-F251 HydrophobicContact CG2-CD2 4.07Å; T247-F251 HydrophobicContact CG2-CE2 3.91Å; T247-F251 WeakPolarHBondContact O-CD2 3.23Å; T247-F251 PolarHBondContact O-N 3.24Å; T247-F251 VanDerWaalsContact O-N 3.16Å; H248-F251 PolarHBondContact O-N 2.9Å; H248-F251 VanDerWaalsContact O-N 3.14Å; S249-F251 VanDerWaalsContact C-N 3.29Å; S249-F251 PolarHBondContact O-N 3.18Å; F251-N254 PolarHBondContact O-N 3.2Å; F251-L255 WeakPolarHBondContact O-CG 3.33Å; F251-L255 PolarHBondContact O-N 3.14Å; F251-L277 HydrophobicContact CD1-CD1 4.44Å; F251-L277 HydrophobicContact CE1-CD1 4.48Å; F251-Q280 HydrophobicContact CE1-CB 4.41Å; F251-Q280 WeakPolarHBondContact CZ-O 3.37Å; F251-F281 HydrophobicContact CB-CD2 4.4Å; F251-F281 HydrophobicContact CB-CE2 4.48Å; F251-F281 HydrophobicContact CD1-CB 4.36Å; F251-F281 AromaticContact CD1-CD2 3.63Å; F251-F281 HydrophobicContact CD1-CD2 3.63Å; F251-F281 HydrophobicContact CD1-CE2 4.47Å; F251-F281 HydrophobicContact CD1-CG 4.48Å; F251-F281 HydrophobicContact CD2-CD2 4.02Å; F251-F281 HydrophobicContact CD2-CE2 4.32Å; F251-F281 VanDerWaalsContact CE1-CA 3.47Å; F251-F281 HydrophobicContact CE1-CB 3.86Å; F251-F281 AromaticContact CE1-CD2 3.88Å; F251-F281 HydrophobicContact CE1-CD2 3.88Å; F251-F281 HydrophobicContact CE1-CG 4.33Å; F251-F281 HydrophobicContact CE2-CD2 4.24Å; F251-F281 AromaticContact CG-CD2 3.73Å; F251-F281 HydrophobicContact CG-CD2 3.73Å; F251-F281 HydrophobicContact CG-CE2 4.16Å; F251-F281 HydrophobicContact CZ-CB 4.2Å; F251-F281 HydrophobicContact CZ-CD2 4.2Å; F251-Y284 HydrophobicContact CZ-CD2 4.03Å; F251-Y284 HydrophobicContact CZ-CG 4.35Å; F251-M285 HydrophobicContact CD2-CG 3.87Å; F251-M285 HydrophobicContact CD2-SD 4.13Å; F251-M285 HydrophobicContact CE2-CG 3.75Å; F251-M285 HydrophobicContact CE2-SD 4.36Å
252V94.7Very high91.3Very high92 Ų9236.2 Ų36.256%0.55819%0.192SC*.Hα-helixtrans-61.9-44.8174.2169.50000111.1H248 S249 L255H248-V252 WeakPolarHBondContact O-CB 3.13Å; H248-V252 VanDerWaalsContact O-CG2 3.31Å; H248-V252 WeakPolarHBondContact O-CG2 3.39Å; H248-V252 PolarHBondContact O-N 2.85Å; S249-V252 PolarHBondContact O-N 3.18Å; V252-L255 WeakPolarHBondContact O-CB 3.41Å; V252-L255 PolarHBondContact O-N 3.12Å
253T94.8Very high90.4Very high25 Ų2537 Ų3715%0.15320%0.201CC..Hα-helixtrans-68.7-37175.956.40000111.3F69 N73 S249 F250 L255 I256 A257F69-T253 HydrophobicContact CD1-CG2 4.1Å; F69-T253 HydrophobicContact CD2-CG2 4.38Å; F69-T253 HydrophobicContact CE1-CG2 4.25Å; F69-T253 HydrophobicContact CG-CG2 4.18Å; F69-T253 HydrophobicContact CZ-CG2 4.46Å; N73-T253 PolarHBondContact ND2-OG1 2.95Å; N73-T253 PolarHBondContact OD1-OG1 3.48Å; S249-T253 WeakPolarHBondContact O-CG2 3.4Å; S249-T253 PolarHBondContact O-N 3.4Å; S249-T253 PolarHBondContact O-OG1 2.79Å; F250-T253 PolarHBondContact O-OG1 3.11Å; T253-L255 VanDerWaalsContact C-N 3.32Å; T253-L255 PolarHBondContact O-N 3.43Å; T253-I256 PolarHBondContact O-N 3.33Å; T253-A257 WeakPolarHBondContact O-CB 3.15Å; T253-A257 PolarHBondContact O-N 3.06Å
254N92.4Very high89.1Confident1 Ų138.5 Ų38.51%0.00521%0.213CC..Hα-helixtrans-67.6-27.3175.9-87.3-69.7000113.6N73 F250 F251 I256 A257 R258 L277N73-N254 VanDerWaalsContact ND2-CG 3.3Å; N73-N254 PolarHBondContact ND2-ND2 3.34Å; F250-N254 WeakPolarHBondContact CE1-ND2 3.15Å; F250-N254 WeakPolarHBondContact CE2-ND2 3.32Å; F250-N254 VanDerWaalsContact CZ-ND2 3.32Å; F250-N254 WeakPolarHBondContact CZ-ND2 3.34Å; F250-N254 VanDerWaalsContact O-CB 3.31Å; F250-N254 WeakPolarHBondContact O-CB 3.25Å; F250-N254 PolarHBondContact O-N 2.85Å; F250-N254 VanDerWaalsContact O-N 3.07Å; F250-N254 PolarHBondContact O-ND2 3.4Å; F251-N254 PolarHBondContact O-N 3.2Å; N254-I256 PolarHBondContact O-N 3.37Å; N254-A257 PolarHBondContact O-N 3.14Å; N254-R258 HydrophobicContact CB-CG 4.17Å; N254-R258 VanDerWaalsContact O-CB 3.24Å; N254-R258 WeakPolarHBondContact O-CB 3.18Å; N254-R258 WeakPolarHBondContact O-CG 3.3Å; N254-R258 PolarHBondContact O-N 3.46Å; N254-R258 WeakPolarHBondContact OD1-CG 3.15Å; N254-R258 PolarHBondContact OD1-NE 2.93Å; N254-L277 HydrophobicContact CB-CD1 3.79Å
255L93Very high87.5Confident15 Ų1538.6 Ų38.68%0.07922%0.224CC..Hα-helixtrans-58.3-27.5172.3-78.2169.6000112.7F39 V42 Y43 I46 F251 V252 T253 Q259F39-L255 HydrophobicContact CD2-CD1 4.32Å; F39-L255 HydrophobicContact CD2-CD2 3.85Å; F39-L255 HydrophobicContact CD2-CG 4.12Å; F39-L255 HydrophobicContact CE1-CD2 4.47Å; F39-L255 HydrophobicContact CE2-CD1 4.27Å; F39-L255 HydrophobicContact CE2-CD2 3.55Å; F39-L255 HydrophobicContact CE2-CG 3.64Å; F39-L255 HydrophobicContact CG-CD2 4.44Å; F39-L255 HydrophobicContact CZ-CD2 3.9Å; F39-L255 HydrophobicContact CZ-CG 4.29Å; V42-L255 HydrophobicContact CB-CD1 4.34Å; V42-L255 HydrophobicContact CG1-CD1 3.66Å; V42-L255 HydrophobicContact CG1-CD2 4.37Å; Y43-L255 HydrophobicContact CD2-CD2 4.21Å; I46-L255 HydrophobicContact CD1-CB 3.8Å; F251-L255 WeakPolarHBondContact O-CG 3.33Å; F251-L255 PolarHBondContact O-N 3.14Å; V252-L255 WeakPolarHBondContact O-CB 3.41Å; V252-L255 PolarHBondContact O-N 3.12Å; T253-L255 VanDerWaalsContact C-N 3.32Å; T253-L255 PolarHBondContact O-N 3.43Å; L255-Q259 VanDerWaalsContact O-CG 3.26Å; L255-Q259 WeakPolarHBondContact O-CG 2.89Å; L255-Q259 PolarHBondContact O-NE2 2.8Å
256I92.7Very high85.6Confident42 Ų4239.8 Ų39.822%0.21523%0.232CC..Hα-helixtrans-95.6-48.9174.6-64168.1000110F62 V65 A66 F69 T253 N254 R258 Q259F62-I256 HydrophobicContact CE1-CG2 4.3Å; F62-I256 HydrophobicContact CE2-CG1 4.5Å; F62-I256 HydrophobicContact CE2-CG2 3.92Å; F62-I256 HydrophobicContact CZ-CB 4.42Å; F62-I256 HydrophobicContact CZ-CG2 3.73Å; V65-I256 HydrophobicContact CG1-CG2 4.24Å; A66-I256 HydrophobicContact CB-CG2 4.03Å; A66-I256 WeakPolarHBondContact CB-O 3.38Å; F69-I256 HydrophobicContact CD2-CB 4.1Å; F69-I256 HydrophobicContact CD2-CD1 4.38Å; F69-I256 HydrophobicContact CD2-CG2 4.11Å; F69-I256 HydrophobicContact CE2-CB 4.47Å; F69-I256 HydrophobicContact CE2-CD1 3.9Å; F69-I256 HydrophobicContact CE2-CG2 4.47Å; T253-I256 PolarHBondContact O-N 3.33Å; N254-I256 PolarHBondContact O-N 3.37Å; I256-R258 PolarHBondContact O-N 3.27Å; I256-R258 VanDerWaalsContact O-N 3.1Å; I256-Q259 PolarHBondContact O-N 2.68Å; I256-Q259 VanDerWaalsContact O-N 3.16Å
257A89.7Confident83.9Confident0 Ų041.8 Ų41.80%024%0.236CC..Hα-helixtrans-60.3-25.9-174.700000114.2A66 F69 T253 N254 R267A66-A257 WeakPolarHBondContact O-CA 3.47Å; F69-A257 HydrophobicContact CB-CB 3.81Å; T253-A257 WeakPolarHBondContact O-CB 3.15Å; T253-A257 PolarHBondContact O-N 3.06Å; N254-A257 PolarHBondContact O-N 3.14Å; A257-R267 PolarHBondContact O-NH1 3.12Å
258R87.8Confident82.1Confident30 Ų3048.8 Ų48.811%0.11327%0.269CS..THydrogen-bonded Turntrans-10716.4-176.8-58.3-68.1-175.9156.4-6.7113.6Y43 N254 I256 L277Y43-R258 PolarHBondContact OH-O 3.23Å; N254-R258 HydrophobicContact CB-CG 4.17Å; N254-R258 VanDerWaalsContact O-CB 3.24Å; N254-R258 WeakPolarHBondContact O-CB 3.18Å; N254-R258 WeakPolarHBondContact O-CG 3.3Å; N254-R258 PolarHBondContact O-N 3.46Å; N254-R258 WeakPolarHBondContact OD1-CG 3.15Å; N254-R258 PolarHBondContact OD1-NE 2.93Å; I256-R258 PolarHBondContact O-N 3.27Å; I256-R258 VanDerWaalsContact O-N 3.1Å; R258-L277 HydrophobicContact CB-CD2 3.91Å; R258-L277 HydrophobicContact CG-CD1 4.24Å; R258-L277 HydrophobicContact CG-CD2 4.29Å
259Q89.1Confident80.4Confident0 Ų047.8 Ų47.80%027%0.266CS..  trans-70.9148.9169.2-68.1-63.1-27.300110.9Y43 I46 N47 F62 L255 I256 T261 R267Y43-Q259 PolarHBondContact O-NE2 3.14Å; I46-Q259 HydrophobicContact CG2-CG 3.76Å; N47-Q259 VanDerWaalsContact CA-OE1 3.3Å; N47-Q259 VanDerWaalsContact CB-OE1 3.29Å; N47-Q259 PolarHBondContact ND2-OE1 3.49Å; N47-Q259 VanDerWaalsContact ND2-OE1 3.13Å; F62-Q259 HydrophobicContact CE1-CB 3.99Å; F62-Q259 HydrophobicContact CE1-CG 4.24Å; F62-Q259 HydrophobicContact CZ-CB 4.18Å; F62-Q259 HydrophobicContact CZ-CG 3.89Å; L255-Q259 VanDerWaalsContact O-CG 3.26Å; L255-Q259 WeakPolarHBondContact O-CG 2.89Å; L255-Q259 PolarHBondContact O-NE2 2.8Å; I256-Q259 PolarHBondContact O-N 2.68Å; I256-Q259 VanDerWaalsContact O-N 3.16Å; Q259-T261 HydrophobicContact CB-CG2 4.49Å; Q259-R267 PolarHBondContact O-NH1 3.46Å
260S82.7Confident79.1Confident2 Ų245.4 Ų45.41%0.01425%0.248CC..  trans-73.8131.7164.655.10000108.8N47 W51 S271N47-S260 PolarHBondContact ND2-OG 3.02Å; W51-S260 PolarHBondContact NE1-O 3.32Å; W51-S260 PolarHBondContact NE1-OG 3.37Å; W51-S260 VanDerWaalsContact NE1-OG 3.1Å; S260-S271 VanDerWaalsContact CB-CB 3.49Å; S260-S271 WeakPolarHBondContact CB-OG 3.42Å; S260-S271 VanDerWaalsContact OG-CB 3.32Å; S260-S271 WeakPolarHBondContact OG-CB 3.09Å; S260-S271 PolarHBondContact OG-OG 3Å
261T83.6Confident77.7Confident13 Ų1346 Ų468%0.0825%0.254CS..  trans-137.9154.8-177.9580000110.2Y50 F62 E63 Q259 S263 A264Y50-T261 HydrophobicContact CD2-CG2 4.19Å; Y50-T261 HydrophobicContact CE1-CG2 4.1Å; Y50-T261 HydrophobicContact CE2-CG2 3.68Å; Y50-T261 VanDerWaalsContact OH-CA 3.3Å; Y50-T261 WeakPolarHBondContact OH-CA 3.31Å; Y50-T261 VanDerWaalsContact OH-CB 3.31Å; Y50-T261 WeakPolarHBondContact OH-CB 3.38Å; F62-T261 HydrophobicContact CD1-CG2 4.17Å; F62-T261 HydrophobicContact CE1-CG2 4.09Å; E63-T261 HydrophobicContact CG-CG2 3.85Å; Q259-T261 HydrophobicContact CB-CG2 4.49Å; T261-S263 VanDerWaalsContact C-N 3.34Å; T261-S263 PolarHBondContact O-N 3Å; T261-A264 PolarHBondContact O-N 2.97Å; T261-A264 VanDerWaalsContact O-N 3.16Å; T261-A264 WeakPolarHBondContact OG1-CB 3.44Å
262Y79.1Confident76.4Confident135 Ų13555.1 Ų55.153%0.52929%0.29SS..SBendtrans-54.6-46.2-179.3-83.4-79.6000111.9Y50 W51 K59 E63 A264Y50-Y262 HydrophobicContact CE1-CD2 4.18Å; Y50-Y262 WeakPolarHBondContact OH-CD2 3.05Å; Y50-Y262 PolarHBondContact OH-N 3.38Å; W51-Y262 AromaticContact CE3-CE2 3.82Å; W51-Y262 HydrophobicContact CE3-CE2 3.82Å; W51-Y262 HydrophobicContact CH2-CD2 4.33Å; W51-Y262 HydrophobicContact CH2-CE2 4.28Å; W51-Y262 HydrophobicContact CH2-CG 4.45Å; W51-Y262 HydrophobicContact CZ3-CD1 4.29Å; W51-Y262 AromaticContact CZ3-CD2 3.95Å; W51-Y262 HydrophobicContact CZ3-CD2 3.95Å; W51-Y262 AromaticContact CZ3-CE1 3.88Å; W51-Y262 HydrophobicContact CZ3-CE1 3.88Å; W51-Y262 AromaticContact CZ3-CE2 3.46Å; W51-Y262 HydrophobicContact CZ3-CE2 3.46Å; W51-Y262 VanDerWaalsContact CZ3-CE2 3.46Å; W51-Y262 HydrophobicContact CZ3-CG 4.34Å; W51-Y262 AromaticContact CZ3-CZ 3.45Å; W51-Y262 VanDerWaalsContact CZ3-CZ 3.45Å; K59-Y262 HydrophobicContact CD-CD2 4.12Å; K59-Y262 HydrophobicContact CD-CE2 4.14Å; E63-Y262 PolarHBondContact OE1-N 3.18Å; Y262-A264 VanDerWaalsContact C-N 3.33Å; Y262-A264 PolarHBondContact O-N 3.4Å
263S73.8Confident75.7Confident94 Ų9456.3 Ų56.366%0.65729%0.288SS*.THydrogen-bonded Turntrans-71.5-25.7-179.8-61.60000113.6E63 T261 G265E63-S263 PolarHBondContact OE1-N 3.47Å; E63-S263 WeakPolarHBondContact OE2-CB 3.45Å; E63-S263 PolarHBondContact OE2-OG 2.97Å; T261-S263 VanDerWaalsContact C-N 3.34Å; T261-S263 PolarHBondContact O-N 3Å; S263-G265 PolarHBondContact O-N 2.84Å; S263-G265 VanDerWaalsContact O-N 3.15Å
264A67.4Low75.3Confident31 Ų3155.2 Ų55.226%0.25628%0.281SS..THydrogen-bonded Turntrans-88.138.1-17600000113T261 Y262 D266 R267T261-A264 PolarHBondContact O-N 2.97Å; T261-A264 VanDerWaalsContact O-N 3.16Å; T261-A264 WeakPolarHBondContact OG1-CB 3.44Å; Y262-A264 VanDerWaalsContact C-N 3.33Å; Y262-A264 PolarHBondContact O-N 3.4Å; A264-D266 PolarHBondContact O-N 3.47Å; A264-R267 HydrophobicContact CB-CG 4.48Å; A264-R267 PolarHBondContact O-N 3.26Å
265G60Low74.9Confident50 Ų5056.4 Ų56.452%0.51529%0.291SS..G310 helixtrans-40.4-18.1-164.900000119S263 R267S263-G265 PolarHBondContact O-N 2.84Å; S263-G265 VanDerWaalsContact O-N 3.15Å; G265-R267 VanDerWaalsContact C-N 3.31Å; G265-R267 PolarHBondContact O-N 3.48Å
266D54.6Low74.4Confident130 Ų13056 Ų5670%0.69529%0.289SS*.G310 helixtrans-72.9-9.5171.5-70-14.8000115.4A264A264-D266 PolarHBondContact O-N 3.47Å
267R56.6Low74.2Confident54 Ų5454 Ų5420%0.20428%0.279CS..G310 helixtrans-99.412.9-173.1-65.6-171.4-171.1173.8-3115.5A257 Q259 A264 G265 I269 E270 S271A257-R267 PolarHBondContact O-NH1 3.12Å; Q259-R267 PolarHBondContact O-NH1 3.46Å; A264-R267 HydrophobicContact CB-CG 4.48Å; A264-R267 PolarHBondContact O-N 3.26Å; G265-R267 VanDerWaalsContact C-N 3.31Å; G265-R267 PolarHBondContact O-N 3.48Å; R267-I269 PolarHBondContact O-N 3.43Å; R267-I269 VanDerWaalsContact O-N 3.14Å; R267-E270 PolarHBondContact O-N 3.23Å; R267-E270 VanDerWaalsContact O-N 3.1Å; R267-S271 PolarHBondContact O-N 3.36Å
268E56.4Low74.2Confident148 Ų14855 Ų5569%0.69228%0.284SS*.Hα-helixtrans-53.6-36.3177.4-73-172.2171.200112.6S271 Y272E268-S271 WeakPolarHBondContact O-CB 3.35Å; E268-S271 PolarHBondContact O-N 2.99Å; E268-Y272 WeakPolarHBondContact O-CD2 3.14Å
269I58.3Low74.1Confident64 Ų6455.3 Ų55.333%0.32829%0.287SS..Hα-helixtrans-69.5-42.1179.6-62.7154.1000111.6R267 S271 Y272 A437 V438 L441R267-I269 PolarHBondContact O-N 3.43Å; R267-I269 VanDerWaalsContact O-N 3.14Å; I269-S271 PolarHBondContact O-N 3.4Å; I269-Y272 PolarHBondContact O-N 3.26Å; I269-A437 HydrophobicContact CD1-CB 4.17Å; I269-V438 HydrophobicContact CD1-CB 4.29Å; I269-V438 HydrophobicContact CD1-CG2 3.46Å; I269-V438 VanDerWaalsContact CD1-CG2 3.46Å; I269-V438 HydrophobicContact CG1-CG2 4.31Å; I269-L441 HydrophobicContact CB-CD2 3.92Å; I269-L441 HydrophobicContact CG2-CD2 3.81Å
270E66.4Low74.1Confident8 Ų855.3 Ų55.34%0.03729%0.288CS..Hα-helixtrans-67-24.4175-69.3-166.614000111.9R267 Y272 F273 L441R267-E270 PolarHBondContact O-N 3.23Å; R267-E270 VanDerWaalsContact O-N 3.1Å; E270-Y272 PolarHBondContact O-N 3.28Å; E270-F273 CarbonylContact O-C 3.55Å; E270-F273 PolarHBondContact O-N 2.72Å; E270-L441 HydrophobicContact CG-CD1 3.64Å; E270-L441 HydrophobicContact CG-CD2 3.7Å; E270-L441 HydrophobicContact CG-CG 4.23Å
271S64.1Low74.5Confident26 Ų2655.7 Ų55.718%0.18229%0.289CS..Hα-helixtrans-55.7-37.7178.5-158.30000112.8S260 R267 E268 I269S260-S271 VanDerWaalsContact CB-CB 3.49Å; S260-S271 WeakPolarHBondContact CB-OG 3.42Å; S260-S271 VanDerWaalsContact OG-CB 3.32Å; S260-S271 WeakPolarHBondContact OG-CB 3.09Å; S260-S271 PolarHBondContact OG-OG 3Å; R267-S271 PolarHBondContact O-N 3.36Å; E268-S271 WeakPolarHBondContact O-CB 3.35Å; E268-S271 PolarHBondContact O-N 2.99Å; I269-S271 PolarHBondContact O-N 3.4Å
272Y68.1Low74.7Confident197 Ų19756.9 Ų56.977%0.77329%0.294SS*.Hα-helixtrans-81.5-37.7-179.3-65.8-79.6000112.9Y44 E268 I269 E270Y44-Y272 PolarHBondContact OH-O 3.29Å; E268-Y272 WeakPolarHBondContact O-CD2 3.14Å; I269-Y272 PolarHBondContact O-N 3.26Å; E270-Y272 PolarHBondContact O-N 3.28Å
273F80.3Confident75.1Confident117 Ų11750.7 Ų50.751%0.51327%0.27SS..  trans-156.9116.2-177.4-174.4-109.4000111.8E270 A275 L278E270-F273 CarbonylContact O-C 3.55Å; E270-F273 PolarHBondContact O-N 2.72Å; F273-A275 HydrophobicContact CD1-CB 3.78Å; F273-A275 HydrophobicContact CE1-CB 3.82Å; F273-A275 PolarHBondContact O-N 2.75Å; F273-L278 HydrophobicContact CE1-CD1 4.29Å; F273-L278 HydrophobicContact CE2-CD1 3.73Å; F273-L278 HydrophobicContact CZ-CD1 3.56Å
274P86Confident75.8Confident2 Ų247 Ų471%0.01324%0.242CC..  trans-81.559.6-17435.6-39.4000112.6Y43 I276 L277 L278Y43-P274 HydrophobicContact CD1-CB 4.33Å; Y43-P274 HydrophobicContact CD1-CG 3.73Å; Y43-P274 HydrophobicContact CD2-CB 4.49Å; Y43-P274 HydrophobicContact CD2-CG 4.46Å; Y43-P274 HydrophobicContact CE1-CB 3.78Å; Y43-P274 HydrophobicContact CE1-CG 3.57Å; Y43-P274 HydrophobicContact CE2-CB 3.96Å; Y43-P274 HydrophobicContact CE2-CG 4.34Å; Y43-P274 HydrophobicContact CG-CG 4.18Å; P274-I276 PolarHBondContact O-N 2.85Å; P274-L277 HydrophobicContact CB-CB 4.22Å; P274-L277 HydrophobicContact CB-CD2 4.46Å; P274-L277 PolarHBondContact O-N 3.27Å; P274-L278 HydrophobicContact CG-CD1 4.23Å; P274-L278 HydrophobicContact CG-CG 4.27Å; P274-L278 WeakPolarHBondContact O-CG 3.19Å; P274-L278 PolarHBondContact O-N 2.62Å
275A82.7Confident77.1Confident26 Ų2645.7 Ų45.722%0.21523%0.231CC..Hα-helixtrans-55-47.4-172.100000113.6F273 L277 L278 I279F273-A275 HydrophobicContact CD1-CB 3.78Å; F273-A275 HydrophobicContact CE1-CB 3.82Å; F273-A275 PolarHBondContact O-N 2.75Å; A275-L277 PolarHBondContact O-N 2.94Å; A275-L278 PolarHBondContact O-N 2.87Å; A275-I279 WeakPolarHBondContact O-CG1 3.01Å; A275-I279 PolarHBondContact O-N 2.69Å
276I82.2Confident78.5Confident6 Ų643.3 Ų43.33%0.03121%0.206CC..Hα-helixtrans-63.3-43.9-177.7-69.1165.5000110.9P274 I279 Q280 L441 F442 G445 L448P274-I276 PolarHBondContact O-N 2.85Å; I276-I279 PolarHBondContact O-N 3.32Å; I276-Q280 VanDerWaalsContact CG2-NE2 3.27Å; I276-Q280 PolarHBondContact O-N 3.29Å; I276-L441 HydrophobicContact CD1-CD1 4Å; I276-L441 HydrophobicContact CD1-CG 3.86Å; I276-L441 WeakPolarHBondContact CD1-O 3.4Å; I276-F442 HydrophobicContact CD1-CD1 3.82Å; I276-F442 HydrophobicContact CD1-CE1 4.31Å; I276-F442 HydrophobicContact CG1-CD1 3.82Å; I276-F442 HydrophobicContact CG1-CE1 4.04Å; I276-G445 VanDerWaalsContact CG2-CA 3.49Å; I276-L448 HydrophobicContact CG2-CD1 4.21Å
277L88.5Confident80.1Confident2 Ų237.1 Ų37.11%0.0117%0.173CC..Hα-helixtrans-65.9-40.6178.7179.359.9000111.3F39 Y43 F251 N254 R258 P274 A275 Q280 F281F39-L277 HydrophobicContact CE1-CD2 3.93Å; F39-L277 HydrophobicContact CE1-CG 3.81Å; F39-L277 HydrophobicContact CZ-CD1 3.94Å; F39-L277 HydrophobicContact CZ-CD2 3.67Å; F39-L277 HydrophobicContact CZ-CG 3.65Å; Y43-L277 HydrophobicContact CD2-CD2 3.8Å; Y43-L277 HydrophobicContact CE2-CD2 3.81Å; F251-L277 HydrophobicContact CD1-CD1 4.44Å; F251-L277 HydrophobicContact CE1-CD1 4.48Å; N254-L277 HydrophobicContact CB-CD1 3.79Å; R258-L277 HydrophobicContact CB-CD2 3.91Å; R258-L277 HydrophobicContact CG-CD1 4.24Å; R258-L277 HydrophobicContact CG-CD2 4.29Å; P274-L277 HydrophobicContact CB-CB 4.22Å; P274-L277 HydrophobicContact CB-CD2 4.46Å; P274-L277 PolarHBondContact O-N 3.27Å; A275-L277 PolarHBondContact O-N 2.94Å; L277-Q280 PolarHBondContact O-N 2.9Å; L277-F281 WeakPolarHBondContact O-CB 3.19Å; L277-F281 PolarHBondContact O-N 3.02Å
278L90Very high81.9Confident19 Ų1934.9 Ų34.910%0.09917%0.165CC..Hα-helixtrans-65.2-38.6175.8-71.4173000112.2F39 F273 P274 A275 F281 L282F39-L278 HydrophobicContact CD1-CD2 3.99Å; F39-L278 HydrophobicContact CE1-CD2 4.2Å; F273-L278 HydrophobicContact CE1-CD1 4.29Å; F273-L278 HydrophobicContact CE2-CD1 3.73Å; F273-L278 HydrophobicContact CZ-CD1 3.56Å; P274-L278 HydrophobicContact CG-CD1 4.23Å; P274-L278 HydrophobicContact CG-CG 4.27Å; P274-L278 WeakPolarHBondContact O-CG 3.19Å; P274-L278 PolarHBondContact O-N 2.62Å; A275-L278 PolarHBondContact O-N 2.87Å; L278-F281 WeakPolarHBondContact O-CB 2.89Å; L278-F281 PolarHBondContact O-N 3.09Å; L278-L282 VanDerWaalsContact O-CG 3.32Å; L278-L282 WeakPolarHBondContact O-CG 3.18Å; L278-L282 PolarHBondContact O-N 3Å
279I86.9Confident83.5Confident37 Ų3728.8 Ų28.819%0.1914%0.136CC..Hα-helixtrans-63-46.1174.5-69.7165.9000110.7A275 I276 F281 L282 F283 I449 L627A275-I279 WeakPolarHBondContact O-CG1 3.01Å; A275-I279 PolarHBondContact O-N 2.69Å; I276-I279 PolarHBondContact O-N 3.32Å; I279-F281 VanDerWaalsContact C-N 3.3Å; I279-F281 PolarHBondContact O-N 3.26Å; I279-L282 PolarHBondContact O-N 3.32Å; I279-F283 WeakPolarHBondContact O-CB 3.3Å; I279-F283 PolarHBondContact O-N 3.21Å; I279-I449 HydrophobicContact CG2-CD1 3.76Å; I279-I449 HydrophobicContact CG2-CG1 4.49Å; I279-L627 HydrophobicContact CD1-CD2 4.43Å
280Q88.3Confident85Confident1 Ų125.7 Ų25.71%0.00512%0.121CC..Hα-helixtrans-60.9-40.9174.5-77.8164.236.500112.1F251 I276 L277 F283 Y284 L448F251-Q280 HydrophobicContact CE1-CB 4.41Å; F251-Q280 WeakPolarHBondContact CZ-O 3.37Å; I276-Q280 VanDerWaalsContact CG2-NE2 3.27Å; I276-Q280 PolarHBondContact O-N 3.29Å; L277-Q280 PolarHBondContact O-N 2.9Å; Q280-F283 PolarHBondContact O-N 3.07Å; Q280-Y284 HydrophobicContact CB-CD2 4.41Å; Q280-Y284 WeakPolarHBondContact O-CD2 3.26Å; Q280-Y284 PolarHBondContact O-N 3.39Å; Q280-L448 HydrophobicContact CG-CB 4.11Å
281F91.4Very high86.2Confident9 Ų925.3 Ų25.34%0.03912%0.119CC..Hα-helixtrans-58.6-56.1176-172.7-88.3000111E35 F39 F251 L277 L278 I279 F283 Y284 M285E35-F281 HydrophobicContact CB-CE1 4.19Å; E35-F281 HydrophobicContact CB-CZ 4.01Å; F39-F281 HydrophobicContact CB-CD2 4.2Å; F39-F281 HydrophobicContact CB-CE1 4.28Å; F39-F281 HydrophobicContact CB-CE2 3.67Å; F39-F281 HydrophobicContact CB-CZ 3.69Å; F39-F281 HydrophobicContact CD1-CB 4.44Å; F39-F281 AromaticContact CD1-CD2 3.79Å; F39-F281 HydrophobicContact CD1-CD2 3.79Å; F39-F281 HydrophobicContact CD1-CE2 4.15Å; F39-F281 HydrophobicContact CD1-CG 4.03Å; F39-F281 AromaticContact CD2-CD2 3.53Å; F39-F281 HydrophobicContact CD2-CD2 3.53Å; F39-F281 AromaticContact CD2-CE2 3.37Å; F39-F281 HydrophobicContact CD2-CE2 3.37Å; F39-F281 HydrophobicContact CD2-CZ 4.27Å; F39-F281 HydrophobicContact CE1-CB 4.26Å; F39-F281 AromaticContact CE1-CD2 3.99Å; F39-F281 HydrophobicContact CE1-CD2 3.99Å; F39-F281 HydrophobicContact CE1-CG 4.25Å; F39-F281 AromaticContact CE2-CD2 3.73Å; F39-F281 HydrophobicContact CE2-CD2 3.73Å; F39-F281 HydrophobicContact CE2-CE2 4Å; F39-F281 AromaticContact CG-CD2 3.55Å; F39-F281 HydrophobicContact CG-CD2 3.55Å; F39-F281 AromaticContact CG-CE2 3.44Å; F39-F281 HydrophobicContact CG-CE2 3.44Å; F39-F281 VanDerWaalsContact CG-CE2 3.44Å; F39-F281 HydrophobicContact CG-CG 4.16Å; F39-F281 AromaticContact CG-CZ 3.98Å; F39-F281 HydrophobicContact CG-CZ 3.98Å; F39-F281 AromaticContact CZ-CD2 3.95Å; F39-F281 HydrophobicContact CZ-CD2 3.95Å; F251-F281 HydrophobicContact CB-CD2 4.4Å; F251-F281 HydrophobicContact CB-CE2 4.48Å; F251-F281 HydrophobicContact CD1-CB 4.36Å; F251-F281 AromaticContact CD1-CD2 3.63Å; F251-F281 HydrophobicContact CD1-CD2 3.63Å; F251-F281 HydrophobicContact CD1-CE2 4.47Å; F251-F281 HydrophobicContact CD1-CG 4.48Å; F251-F281 HydrophobicContact CD2-CD2 4.02Å; F251-F281 HydrophobicContact CD2-CE2 4.32Å; F251-F281 VanDerWaalsContact CE1-CA 3.47Å; F251-F281 HydrophobicContact CE1-CB 3.86Å; F251-F281 AromaticContact CE1-CD2 3.88Å; F251-F281 HydrophobicContact CE1-CD2 3.88Å; F251-F281 HydrophobicContact CE1-CG 4.33Å; F251-F281 HydrophobicContact CE2-CD2 4.24Å; F251-F281 AromaticContact CG-CD2 3.73Å; F251-F281 HydrophobicContact CG-CD2 3.73Å; F251-F281 HydrophobicContact CG-CE2 4.16Å; F251-F281 HydrophobicContact CZ-CB 4.2Å; F251-F281 HydrophobicContact CZ-CD2 4.2Å; L277-F281 WeakPolarHBondContact O-CB 3.19Å; L277-F281 PolarHBondContact O-N 3.02Å; L278-F281 WeakPolarHBondContact O-CB 2.89Å; L278-F281 PolarHBondContact O-N 3.09Å; I279-F281 VanDerWaalsContact C-N 3.3Å; I279-F281 PolarHBondContact O-N 3.26Å; F281-F283 PolarHBondContact O-N 3.25Å; F281-F283 VanDerWaalsContact O-N 3.15Å; F281-Y284 PolarHBondContact O-N 3.44Å; F281-M285 HydrophobicContact CD1-CB 4.33Å; F281-M285 HydrophobicContact CD1-CG 4.25Å; F281-M285 HydrophobicContact CD2-CG 3.88Å; F281-M285 HydrophobicContact CE1-CB 4.13Å; F281-M285 HydrophobicContact CE1-CG 3.97Å; F281-M285 HydrophobicContact CE2-CG 3.57Å; F281-M285 HydrophobicContact CG-CG 4.22Å; F281-M285 HydrophobicContact CZ-CB 4.27Å; F281-M285 HydrophobicContact CZ-CG 3.63Å; F281-M285 WeakPolarHBondContact O-CA 3.11Å; F281-M285 WeakPolarHBondContact O-CB 3.37Å; F281-M285 PolarHBondContact O-N 3.19Å
282L88.7Confident87.4Confident38 Ų3829 Ų2920%0.19913%0.133CC..Hα-helixtrans-54.4-37.3177.4-71174.1000111.9L32 L278 I279 G286L32-L282 HydrophobicContact CD1-CD2 3.75Å; L278-L282 VanDerWaalsContact O-CG 3.32Å; L278-L282 WeakPolarHBondContact O-CG 3.18Å; L278-L282 PolarHBondContact O-N 3Å; I279-L282 PolarHBondContact O-N 3.32Å; L282-G286 WeakPolarHBondContact O-CA 3.45Å; L282-G286 PolarHBondContact O-N 3.29Å
283F85.9Confident88.3Confident5 Ų519.9 Ų19.92%0.02210%0.098CC..Hα-helixtrans-70.4-62.1178.8175.3-99.9000113.4I279 Q280 F281 G286 W287 P450 V454 V616 A620I279-F283 WeakPolarHBondContact O-CB 3.3Å; I279-F283 PolarHBondContact O-N 3.21Å; Q280-F283 PolarHBondContact O-N 3.07Å; F281-F283 PolarHBondContact O-N 3.25Å; F281-F283 VanDerWaalsContact O-N 3.15Å; F283-G286 PolarHBondContact O-N 3.45Å; F283-W287 HydrophobicContact CE1-CE3 4.45Å; F283-W287 HydrophobicContact CZ-CE3 4.41Å; F283-W287 WeakPolarHBondContact O-CB 3.35Å; F283-W287 PolarHBondContact O-N 3.27Å; F283-P450 VanDerWaalsContact CE1-CD 3.41Å; F283-P450 HydrophobicContact CE1-CG 3.39Å; F283-P450 HydrophobicContact CZ-CG 3.59Å; F283-V454 HydrophobicContact CE1-CG2 4.23Å; F283-V454 HydrophobicContact CE2-CB 3.95Å; F283-V454 HydrophobicContact CE2-CG1 4.04Å; F283-V454 HydrophobicContact CE2-CG2 3.45Å; F283-V454 VanDerWaalsContact CE2-CG2 3.45Å; F283-V454 HydrophobicContact CZ-CB 3.99Å; F283-V454 HydrophobicContact CZ-CG2 3.16Å; F283-V616 HydrophobicContact CD2-CG1 4.4Å; F283-A620 HydrophobicContact CD2-CB 3.53Å; F283-A620 HydrophobicContact CE2-CB 3.42Å; F283-A620 VanDerWaalsContact CE2-CB 3.42Å
284Y90Very high88.7Confident16 Ų1614.4 Ų14.46%0.0637%0.074CC..Hα-helixtrans-72.4-42.2-174.1-72.5-70.9000111.9L78 T79 F250 F251 Q280 F281 G286 W287 L288 P450L78-Y284 HydrophobicContact CB-CE1 4.23Å; L78-Y284 HydrophobicContact CD2-CD1 3.61Å; L78-Y284 HydrophobicContact CD2-CD2 4.26Å; L78-Y284 HydrophobicContact CD2-CE1 3.92Å; L78-Y284 HydrophobicContact CD2-CG 3.79Å; L78-Y284 HydrophobicContact CG-CD1 3.84Å; L78-Y284 HydrophobicContact CG-CE1 3.94Å; T79-Y284 PolarHBondContact OG1-OH 3Å; T79-Y284 VanDerWaalsContact OG1-OH 3.1Å; F250-Y284 HydrophobicContact CE1-CD2 4.19Å; F250-Y284 HydrophobicContact CE1-CE2 4.29Å; F250-Y284 HydrophobicContact CZ-CE2 4.45Å; F251-Y284 HydrophobicContact CZ-CD2 4.03Å; F251-Y284 HydrophobicContact CZ-CG 4.35Å; Q280-Y284 HydrophobicContact CB-CD2 4.41Å; Q280-Y284 WeakPolarHBondContact O-CD2 3.26Å; Q280-Y284 PolarHBondContact O-N 3.39Å; F281-Y284 PolarHBondContact O-N 3.44Å; Y284-G286 VanDerWaalsContact C-N 3.34Å; Y284-W287 PolarHBondContact O-N 2.92Å; Y284-L288 PolarHBondContact O-N 3.46Å; Y284-P450 HydrophobicContact CE1-CG 4.2Å; Y284-P450 WeakPolarHBondContact OH-CD 3.36Å; Y284-P450 WeakPolarHBondContact OH-CG 3.48Å
285M93.1Very high88.8Confident5 Ų516.4 Ų16.43%0.0258%0.084CC..Hα-helixtrans-67.6-38.2172.8-71.2-63.2-63.900110.9L32 E35 T247 F251 F281 W287 L288 K289L32-M285 HydrophobicContact CD2-CB 3.84Å; E35-M285 HydrophobicContact CG-CE 4.39Å; T247-M285 HydrophobicContact CG2-CG 4.43Å; T247-M285 HydrophobicContact CG2-SD 3.57Å; T247-M285 VanDerWaalsContact CG2-SD 3.57Å; F251-M285 HydrophobicContact CD2-CG 3.87Å; F251-M285 HydrophobicContact CD2-SD 4.13Å; F251-M285 HydrophobicContact CE2-CG 3.75Å; F251-M285 HydrophobicContact CE2-SD 4.36Å; F281-M285 HydrophobicContact CD1-CB 4.33Å; F281-M285 HydrophobicContact CD1-CG 4.25Å; F281-M285 HydrophobicContact CD2-CG 3.88Å; F281-M285 HydrophobicContact CE1-CB 4.13Å; F281-M285 HydrophobicContact CE1-CG 3.97Å; F281-M285 HydrophobicContact CE2-CG 3.57Å; F281-M285 HydrophobicContact CG-CG 4.22Å; F281-M285 HydrophobicContact CZ-CB 4.27Å; F281-M285 HydrophobicContact CZ-CG 3.63Å; F281-M285 WeakPolarHBondContact O-CA 3.11Å; F281-M285 WeakPolarHBondContact O-CB 3.37Å; F281-M285 PolarHBondContact O-N 3.19Å; M285-W287 VanDerWaalsContact C-N 3.33Å; M285-W287 PolarHBondContact O-N 3.32Å; M285-L288 HydrophobicContact CE-CD2 4.42Å; M285-L288 WeakPolarHBondContact O-CB 3.39Å; M285-L288 PolarHBondContact O-N 3.12Å; M285-L288 HydrophobicContact SD-CD2 4.21Å; M285-K289 WeakPolarHBondContact O-CB 3.27Å; M285-K289 WeakPolarHBondContact O-CG 3.28Å; M285-K289 PolarHBondContact O-N 3.05Å
286G89.4Confident88.8Confident0 Ų020.5 Ų20.50%010%0.101CC..Hα-helixtrans-59.1-44.7173.500000112.3L282 F283 Y284 L288 K289 V290L282-G286 WeakPolarHBondContact O-CA 3.45Å; L282-G286 PolarHBondContact O-N 3.29Å; F283-G286 PolarHBondContact O-N 3.45Å; Y284-G286 VanDerWaalsContact C-N 3.34Å; G286-L288 VanDerWaalsContact C-N 3.32Å; G286-L288 PolarHBondContact O-N 3.45Å; G286-K289 CarbonylContact O-C 3.44Å; G286-K289 PolarHBondContact O-N 3.34Å; G286-V290 VanDerWaalsContact O-CG2 3.31Å; G286-V290 WeakPolarHBondContact O-CG2 3.33Å; G286-V290 PolarHBondContact O-N 3.44Å
287W89.8Confident89.1Confident0 Ų020.5 Ų20.50%010%0.101CC..Hα-helixtrans-66.8-34.8178.1-150.313.8000112.2T79 M82 V86 F283 Y284 M285 V290 A291 V454 F457 Y613 V616T79-W287 HydrophobicContact CG2-CZ3 4.13Å; M82-W287 HydrophobicContact CB-CD2 4.25Å; M82-W287 HydrophobicContact CB-CE3 3.6Å; M82-W287 HydrophobicContact CB-CH2 4.48Å; M82-W287 HydrophobicContact CB-CZ3 3.73Å; M82-W287 HydrophobicContact CE-CB 3.98Å; M82-W287 HydrophobicContact CE-CG 4.44Å; M82-W287 HydrophobicContact CG-CE3 4.49Å; V86-W287 HydrophobicContact CG2-CD2 4.26Å; V86-W287 HydrophobicContact CG2-CG 3.95Å; V86-W287 WeakPolarHBondContact CG2-O 3.49Å; F283-W287 HydrophobicContact CE1-CE3 4.45Å; F283-W287 HydrophobicContact CZ-CE3 4.41Å; F283-W287 WeakPolarHBondContact O-CB 3.35Å; F283-W287 PolarHBondContact O-N 3.27Å; Y284-W287 PolarHBondContact O-N 2.92Å; M285-W287 VanDerWaalsContact C-N 3.33Å; M285-W287 PolarHBondContact O-N 3.32Å; W287-V290 WeakPolarHBondContact O-CB 3.27Å; W287-V290 PolarHBondContact O-N 3.44Å; W287-A291 PolarHBondContact O-N 3.47Å; W287-V454 HydrophobicContact CD2-CG2 3.78Å; W287-V454 HydrophobicContact CE3-CG2 3.49Å; W287-V454 VanDerWaalsContact CE3-CG2 3.49Å; W287-V454 HydrophobicContact CH2-CB 4.34Å; W287-V454 HydrophobicContact CH2-CG2 3.24Å; W287-V454 HydrophobicContact CZ2-CB 4.39Å; W287-V454 HydrophobicContact CZ2-CG2 3.51Å; W287-V454 HydrophobicContact CZ3-CG2 3.23Å; W287-F457 HydrophobicContact CH2-CD2 4.36Å; W287-F457 HydrophobicContact CZ2-CD2 4.36Å; W287-Y613 AromaticContact NE1-CE2 3.82Å; W287-V616 HydrophobicContact CB-CG1 4.23Å; W287-V616 HydrophobicContact CG-CG1 4.41Å
288L93Very high88.9Confident6 Ų621 Ų213%0.03110%0.104CC..Hα-helixtrans-64.2-44.4170.7-176.363.2000111.5M82 F85 V243 T247 Y284 M285 G286 V290 A291 E292M82-L288 HydrophobicContact CE-CB 3.6Å; M82-L288 HydrophobicContact CE-CD1 4.18Å; M82-L288 HydrophobicContact SD-CD1 4.42Å; F85-L288 HydrophobicContact CE1-CD1 4.47Å; V243-L288 HydrophobicContact CG1-CD1 4.08Å; T247-L288 HydrophobicContact CG2-CD2 4.04Å; Y284-L288 PolarHBondContact O-N 3.46Å; M285-L288 HydrophobicContact CE-CD2 4.42Å; M285-L288 WeakPolarHBondContact O-CB 3.39Å; M285-L288 PolarHBondContact O-N 3.12Å; M285-L288 HydrophobicContact SD-CD2 4.21Å; G286-L288 VanDerWaalsContact C-N 3.32Å; G286-L288 PolarHBondContact O-N 3.45Å; L288-V290 VanDerWaalsContact C-N 3.34Å; L288-V290 PolarHBondContact O-N 3.32Å; L288-A291 PolarHBondContact O-N 3.47Å; L288-A291 VanDerWaalsContact O-N 3.1Å; L288-E292 PolarHBondContact O-N 3.2Å
289K91Very high88.6Confident20 Ų2020.9 Ų20.99%0.08711%0.107CC..Hα-helixtrans-64.9-34.4175.9-72.7-54.6-170179.50113.2I31 L32 E35 M285 G286 A291 E292 V293I31-K289 HydrophobicContact CG2-CB 3.79Å; I31-K289 HydrophobicContact CG2-CD 3.81Å; I31-K289 HydrophobicContact CG2-CG 3.77Å; L32-K289 HydrophobicContact CD2-CB 4.34Å; L32-K289 HydrophobicContact CD2-CG 3.53Å; L32-K289 HydrophobicContact CG-CG 4.46Å; E35-K289 WeakPolarHBondContact OE1-CE 3.5Å; E35-K289 IonicContact OE1-NZ 3.34Å; E35-K289 PolarHBondContact OE1-NZ 3.36Å; M285-K289 WeakPolarHBondContact O-CB 3.27Å; M285-K289 WeakPolarHBondContact O-CG 3.28Å; M285-K289 PolarHBondContact O-N 3.05Å; G286-K289 CarbonylContact O-C 3.44Å; G286-K289 PolarHBondContact O-N 3.34Å; K289-A291 VanDerWaalsContact C-N 3.32Å; K289-A291 PolarHBondContact O-N 2.85Å; K289-E292 HydrophobicContact CD-CB 4.48Å; K289-E292 WeakPolarHBondContact CD-OE2 3.41Å; K289-E292 WeakPolarHBondContact CE-OE2 3.43Å; K289-E292 VanDerWaalsContact NZ-CD 3.32Å; K289-E292 IonicContact NZ-OE1 3.38Å; K289-E292 PolarHBondContact NZ-OE1 2.98Å; K289-E292 VanDerWaalsContact NZ-OE1 3.1Å; K289-E292 IonicContact NZ-OE2 2.66Å; K289-E292 PolarHBondContact NZ-OE2 3.44Å; K289-E292 PolarHBondContact O-N 3.48Å; K289-V293 WeakPolarHBondContact O-CG2 3.37Å; K289-V293 PolarHBondContact O-N 3.27Å
290V89.7Confident88.3Confident0 Ų024.3 Ų24.30%012%0.123CC..Hα-helixtrans-57.2-48169.4172.40000109.9V86 G286 W287 L288 L294 V612 Y613 V616V86-V290 HydrophobicContact CG1-CG1 4.25Å; G286-V290 VanDerWaalsContact O-CG2 3.31Å; G286-V290 WeakPolarHBondContact O-CG2 3.33Å; G286-V290 PolarHBondContact O-N 3.44Å; W287-V290 WeakPolarHBondContact O-CB 3.27Å; W287-V290 PolarHBondContact O-N 3.44Å; L288-V290 VanDerWaalsContact C-N 3.34Å; L288-V290 PolarHBondContact O-N 3.32Å; V290-L294 HydrophobicContact CG1-CD1 3.86Å; V290-L294 WeakPolarHBondContact O-CB 3.24Å; V290-L294 WeakPolarHBondContact O-CD1 3.01Å; V290-L294 WeakPolarHBondContact O-CG 3.4Å; V290-L294 PolarHBondContact O-N 3.2Å; V290-V612 HydrophobicContact CG2-CB 4.26Å; V290-V612 HydrophobicContact CG2-CG1 3.95Å; V290-V612 HydrophobicContact CG2-CG2 3.68Å; V290-Y613 HydrophobicContact CG1-CD1 4.37Å; V290-Y613 HydrophobicContact CG1-CD2 4.34Å; V290-Y613 HydrophobicContact CG1-CG 3.96Å; V290-V616 HydrophobicContact CG2-CB 4.46Å; V290-V616 HydrophobicContact CG2-CG2 3.73Å
291A90.9Very high88Confident0 Ų028.5 Ų28.50%015%0.145CC..Hα-helixtrans-67.2-39177.700000112.4F85 V86 V89 W287 L288 K289 L294 I295F85-A291 HydrophobicContact CD1-CB 3.71Å; F85-A291 HydrophobicContact CE1-CB 3.39Å; F85-A291 HydrophobicContact CZ-CB 4.35Å; V86-A291 HydrophobicContact CG2-CB 3.94Å; V89-A291 HydrophobicContact CB-CB 4.39Å; V89-A291 HydrophobicContact CG1-CB 4.46Å; V89-A291 WeakPolarHBondContact CG1-O 3.47Å; V89-A291 HydrophobicContact CG2-CB 4.06Å; W287-A291 PolarHBondContact O-N 3.47Å; L288-A291 PolarHBondContact O-N 3.47Å; L288-A291 VanDerWaalsContact O-N 3.1Å; K289-A291 VanDerWaalsContact C-N 3.32Å; K289-A291 PolarHBondContact O-N 2.85Å; A291-L294 PolarHBondContact O-N 3.18Å; A291-I295 WeakPolarHBondContact O-CB 2.99Å; A291-I295 PolarHBondContact O-N 3.49Å
292E89.3Confident87.6Confident103 Ų10329.7 Ų29.748%0.48115%0.152SC..Hα-helixtrans-58-50178-170.5179.7143.700111.5L288 K289 L294 I295L288-E292 PolarHBondContact O-N 3.2Å; K289-E292 HydrophobicContact CD-CB 4.48Å; K289-E292 WeakPolarHBondContact CD-OE2 3.41Å; K289-E292 WeakPolarHBondContact CE-OE2 3.43Å; K289-E292 VanDerWaalsContact NZ-CD 3.32Å; K289-E292 IonicContact NZ-OE1 3.38Å; K289-E292 PolarHBondContact NZ-OE1 2.98Å; K289-E292 VanDerWaalsContact NZ-OE1 3.1Å; K289-E292 IonicContact NZ-OE2 2.66Å; K289-E292 PolarHBondContact NZ-OE2 3.44Å; K289-E292 PolarHBondContact O-N 3.48Å; E292-L294 VanDerWaalsContact C-N 3.28Å; E292-L294 PolarHBondContact O-N 2.86Å; E292-I295 WeakPolarHBondContact O-CG2 3.19Å; E292-I295 PolarHBondContact O-N 3.2Å
293V86.6Confident87.2Confident6 Ų628.3 Ų28.34%0.03615%0.145CC..Hα-helixtrans-65-32.3179173.50000111.9I31 K289 D301 D303I31-V293 HydrophobicContact CD1-CG2 3.93Å; K289-V293 WeakPolarHBondContact O-CG2 3.37Å; K289-V293 PolarHBondContact O-N 3.27Å; V293-D301 HydrophobicContact CG1-CB 4.16Å; V293-D303 HydrophobicContact CG1-CB 3.77Å
294L90Very high87.2Confident2 Ų228.5 Ų28.51%0.0115%0.146CC..Hα-helixtrans-86.3-14.8-176.7-62.4176.3000114.6V89 Y90 W93 V290 A291 E292 I296 P610V89-L294 HydrophobicContact CG1-CB 3.68Å; Y90-L294 HydrophobicContact CD2-CD1 4.16Å; W93-L294 HydrophobicContact CB-CB 4.26Å; W93-L294 VanDerWaalsContact CD1-CD2 3.48Å; W93-L294 HydrophobicContact CD2-CD2 4.07Å; W93-L294 HydrophobicContact CG-CB 4.25Å; W93-L294 HydrophobicContact CG-CD2 3.9Å; V290-L294 HydrophobicContact CG1-CD1 3.86Å; V290-L294 WeakPolarHBondContact O-CB 3.24Å; V290-L294 WeakPolarHBondContact O-CD1 3.01Å; V290-L294 WeakPolarHBondContact O-CG 3.4Å; V290-L294 PolarHBondContact O-N 3.2Å; A291-L294 PolarHBondContact O-N 3.18Å; E292-L294 VanDerWaalsContact C-N 3.28Å; E292-L294 PolarHBondContact O-N 2.86Å; L294-I296 VanDerWaalsContact C-N 3.32Å; L294-I296 PolarHBondContact O-N 2.98Å; L294-P610 HydrophobicContact CD1-CG 3.99Å; L294-P610 HydrophobicContact CD2-CB 4.08Å; L294-P610 HydrophobicContact CD2-CG 3.31Å; L294-P610 HydrophobicContact CG-CG 4.2Å
295I86.7Confident87.1Confident43 Ų4328.2 Ų28.222%0.22115%0.145CC..Hα-helixtrans-71.2-29.3-175.8-157.5168.3000112.3F85 V89 L235 A291 E292F85-I295 HydrophobicContact CZ-CD1 4.47Å; V89-I295 HydrophobicContact CG1-CB 4.18Å; L235-I295 HydrophobicContact CB-CD1 4.44Å; L235-I295 HydrophobicContact CD1-CD1 4.13Å; L235-I295 HydrophobicContact CD1-CG1 4.2Å; A291-I295 WeakPolarHBondContact O-CB 2.99Å; A291-I295 PolarHBondContact O-N 3.49Å; E292-I295 WeakPolarHBondContact O-CG2 3.19Å; E292-I295 PolarHBondContact O-N 3.2Å
296I83.8Confident86.8Confident113 Ų11330.2 Ų30.258%0.57915%0.154SC*.  trans-126.277.6179.5-56.2168.4000109.3L294 F298 G299L294-I296 VanDerWaalsContact C-N 3.32Å; L294-I296 PolarHBondContact O-N 2.98Å; I296-F298 PolarHBondContact O-N 3.36Å; I296-G299 PolarHBondContact O-N 3.27Å
297P87.7Confident86.7Confident5 Ų530.3 Ų30.33%0.03216%0.155CC..THydrogen-bonded Turntrans-71.44.2-175.529.3-36000115.5N96 D304 F305N96-P297 HydrophobicContact CB-CG 4.13Å; P297-D304 VanDerWaalsContact C-OD1 3.26Å; P297-D304 WeakPolarHBondContact CA-OD1 3.44Å; P297-F305 HydrophobicContact CB-CD2 3.78Å; P297-F305 HydrophobicContact CB-CE1 4.36Å; P297-F305 HydrophobicContact CB-CE2 3.44Å; P297-F305 VanDerWaalsContact CB-CE2 3.44Å; P297-F305 HydrophobicContact CB-CG 4.36Å; P297-F305 HydrophobicContact CB-CZ 3.72Å; P297-F305 HydrophobicContact CG-CD2 4.34Å; P297-F305 HydrophobicContact CG-CE2 3.82Å; P297-F305 HydrophobicContact CG-CZ 4.38Å; P297-F305 PolarHBondContact O-N 2.87Å
298F85.7Confident86.7Confident13 Ų1332.5 Ų32.56%0.05717%0.166CC..THydrogen-bonded Turntrans-111.813.3-174.8-60-73.5000112.3N96 L100 S144 L227 I296 F305 I307N96-F298 HydrophobicContact CB-CE2 4.2Å; N96-F298 HydrophobicContact CB-CZ 4.15Å; L100-F298 HydrophobicContact CD2-CE1 3.93Å; S144-F298 PolarHBondContact OG-O 3.44Å; L227-F298 HydrophobicContact CD2-CZ 3.77Å; I296-F298 PolarHBondContact O-N 3.36Å; F298-F305 HydrophobicContact CD1-CD2 4.45Å; F298-F305 HydrophobicContact CE1-CD2 4.06Å; F298-F305 HydrophobicContact CZ-CD2 4.4Å; F298-I307 HydrophobicContact CD1-CD1 3.71Å; F298-I307 HydrophobicContact CD1-CG1 3.89Å; F298-I307 HydrophobicContact CE1-CD1 3.89Å
299G82.7Confident86.5Confident17 Ų1736.2 Ų36.218%0.17518%0.18CC..SBendtrans-84.6-143.4-179.400000113.4V146 I296 D304V146-G299 WeakPolarHBondContact CG2-O 3.31Å; I296-G299 PolarHBondContact O-N 3.27Å; G299-D304 WeakPolarHBondContact CA-OD2 3.38Å; G299-D304 PolarHBondContact N-OD2 3.05Å
300E81.2Confident86.5Confident109 Ų10935.2 Ų35.251%0.50918%0.176SC..SBendtrans-124.68.9-175.5-74.7173.2-155.500113.5V146 K149 D304V146-E300 HydrophobicContact CG2-CG 3.35Å; K149-E300 WeakPolarHBondContact CD-OE1 3.1Å; K149-E300 WeakPolarHBondContact CE-OE1 2.99Å; K149-E300 IonicContact NZ-OE1 2.82Å; K149-E300 PolarHBondContact NZ-OE1 3.4Å; K149-E300 IonicContact NZ-OE2 2.97Å; K149-E300 PolarHBondContact NZ-OE2 2.96Å; E300-D304 PolarHBondContact N-OD2 3.33Å
301D82.4Confident86.5Confident88 Ų8835.4 Ų35.447%0.47118%0.177SC..SBendtrans-72.5162.4178.6-69.8-32.1000111.4V293 D303 D304V293-D301 HydrophobicContact CG1-CB 4.16Å; D301-D303 PolarHBondContact O-N 2.85Å; D301-D304 PolarHBondContact N-OD2 3.39Å; D301-D304 WeakPolarHBondContact O-CB 3.17Å; D301-D304 PolarHBondContact O-N 2.93Å
302D81.4Confident86.5Confident35 Ų3538 Ų3819%0.18719%0.191CC..THydrogen-bonded Turntrans-62.8-27-175.8-71.6-20.7000112.8I3 G26 K30I3-D302 HydrophobicContact CD1-CB 4.15Å; G26-D302 WeakPolarHBondContact CA-OD2 3.33Å; G26-D302 PolarHBondContact N-OD2 3.17Å; K30-D302 IonicContact NZ-OD1 2.91Å; K30-D302 PolarHBondContact NZ-OD1 3.44Å; K30-D302 IonicContact NZ-OD2 3.27Å; K30-D302 PolarHBondContact NZ-OD2 3.24Å
303D81.5Confident86.5Confident9 Ų933.8 Ų33.85%0.04817%0.171CC..THydrogen-bonded Turntrans-96.80.1-178.6-64.6-78.3000113.5V293 D301V293-D303 HydrophobicContact CG1-CB 3.77Å; D301-D303 PolarHBondContact O-N 2.85Å
304D85.2Confident86.9Confident9 Ų933.6 Ų33.65%0.04817%0.17CC..SBendtrans-70.4156.4179-76.4-29.9000112.7T2 P297 G299 E300 D301T2-D304 PolarHBondContact OG1-O 3.3Å; T2-D304 VanDerWaalsContact OG1-O 3.11Å; P297-D304 VanDerWaalsContact C-OD1 3.26Å; P297-D304 WeakPolarHBondContact CA-OD1 3.44Å; G299-D304 WeakPolarHBondContact CA-OD2 3.38Å; G299-D304 PolarHBondContact N-OD2 3.05Å; E300-D304 PolarHBondContact N-OD2 3.33Å; D301-D304 PolarHBondContact N-OD2 3.39Å; D301-D304 WeakPolarHBondContact O-CB 3.17Å; D301-D304 PolarHBondContact O-N 2.93Å
305F88.8Confident87Confident10 Ų1034.8 Ų34.84%0.04418%0.177CC..  trans-70.6135.6179.2-58-31000111W93 N96 F97 L100 P297 F298 I307 V607W93-F305 HydrophobicContact CD2-CE1 4.43Å; W93-F305 HydrophobicContact CD2-CZ 4.2Å; W93-F305 AromaticContact CE2-CE1 3.54Å; W93-F305 AromaticContact CE2-CZ 3.7Å; W93-F305 HydrophobicContact CG-CZ 4.36Å; W93-F305 HydrophobicContact CH2-CE1 4.47Å; W93-F305 AromaticContact CZ2-CE1 3.57Å; W93-F305 HydrophobicContact CZ2-CE1 3.57Å; W93-F305 HydrophobicContact CZ2-CZ 4.15Å; W93-F305 AromaticContact NE1-CE1 3.54Å; W93-F305 AromaticContact NE1-CZ 3.57Å; N96-F305 HydrophobicContact CB-CE2 4.25Å; F97-F305 HydrophobicContact CB-CE1 4.02Å; F97-F305 HydrophobicContact CB-CE2 3.93Å; F97-F305 HydrophobicContact CB-CZ 3.47Å; F97-F305 VanDerWaalsContact CB-CZ 3.47Å; F97-F305 AromaticContact CD2-CD1 3.98Å; F97-F305 HydrophobicContact CD2-CD1 3.98Å; F97-F305 AromaticContact CD2-CE1 3.72Å; F97-F305 HydrophobicContact CD2-CE1 3.72Å; F97-F305 HydrophobicContact CD2-CE2 4.34Å; F97-F305 HydrophobicContact CD2-CG 4.43Å; F97-F305 AromaticContact CD2-CZ 3.95Å; F97-F305 HydrophobicContact CD2-CZ 3.95Å; F97-F305 HydrophobicContact CG-CE1 4.19Å; F97-F305 HydrophobicContact CG-CZ 4.13Å; L100-F305 HydrophobicContact CD1-CD2 3.96Å; L100-F305 HydrophobicContact CD1-CE2 4.5Å; L100-F305 HydrophobicContact CD1-CG 4.28Å; P297-F305 HydrophobicContact CB-CD2 3.78Å; P297-F305 HydrophobicContact CB-CE1 4.36Å; P297-F305 HydrophobicContact CB-CE2 3.44Å; P297-F305 VanDerWaalsContact CB-CE2 3.44Å; P297-F305 HydrophobicContact CB-CG 4.36Å; P297-F305 HydrophobicContact CB-CZ 3.72Å; P297-F305 HydrophobicContact CG-CD2 4.34Å; P297-F305 HydrophobicContact CG-CE2 3.82Å; P297-F305 HydrophobicContact CG-CZ 4.38Å; P297-F305 PolarHBondContact O-N 2.87Å; F298-F305 HydrophobicContact CD1-CD2 4.45Å; F298-F305 HydrophobicContact CE1-CD2 4.06Å; F298-F305 HydrophobicContact CZ-CD2 4.4Å; F305-I307 VanDerWaalsContact C-N 3.29Å; F305-I307 HydrophobicContact CB-CD1 3.55Å; F305-I307 HydrophobicContact CB-CG1 4.38Å; F305-I307 WeakPolarHBondContact O-CG1 3.44Å; F305-I307 PolarHBondContact O-N 3.12Å; F305-V607 HydrophobicContact CD1-CG1 4.2Å; F305-V607 HydrophobicContact CE1-CG1 3.93Å
306E86.1Confident87.2Confident47 Ų4736 Ų3622%0.2218%0.182CC..  trans-77.574.9178.1-59.8-169.9-167.700112.5M1 T2 N308 Y309 I310 W606M1-E306 VanDerWaalsContact C-OE1 3.27Å; M1-E306 WeakPolarHBondContact CA-OE1 3.47Å; M1-E306 WeakPolarHBondContact CB-OE1 3.16Å; M1-E306 VanDerWaalsContact CG-OE1 3.3Å; M1-E306 WeakPolarHBondContact CG-OE1 3.36Å; T2-E306 PolarHBondContact N-OE1 2.91Å; E306-N308 PolarHBondContact O-N 3.18Å; E306-Y309 PolarHBondContact O-N 3.36Å; E306-I310 PolarHBondContact O-N 2.81Å; E306-W606 HydrophobicContact CB-CH2 3.97Å; E306-W606 HydrophobicContact CB-CZ2 3.81Å; E306-W606 HydrophobicContact CG-CZ2 4.15Å
307I88.3Confident87.5Confident2 Ų230.7 Ų30.71%0.0115%0.154CC..Hα-helixtrans-66.4-35.1-173.3-51.6-52.1000112.8L100 L140 V147 F298 F305 Y309 I310 V311L100-I307 HydrophobicContact CD2-CD1 3.8Å; L140-I307 HydrophobicContact CB-CG2 4.04Å; L140-I307 HydrophobicContact CD1-CG2 3.82Å; L140-I307 HydrophobicContact CD2-CG2 3.76Å; L140-I307 HydrophobicContact CG-CG2 4.07Å; V147-I307 HydrophobicContact CG2-CB 3.81Å; V147-I307 HydrophobicContact CG2-CG2 3.33Å; F298-I307 HydrophobicContact CD1-CD1 3.71Å; F298-I307 HydrophobicContact CD1-CG1 3.89Å; F298-I307 HydrophobicContact CE1-CD1 3.89Å; F305-I307 VanDerWaalsContact C-N 3.29Å; F305-I307 HydrophobicContact CB-CD1 3.55Å; F305-I307 HydrophobicContact CB-CG1 4.38Å; F305-I307 WeakPolarHBondContact O-CG1 3.44Å; F305-I307 PolarHBondContact O-N 3.12Å; I307-Y309 VanDerWaalsContact C-N 3.33Å; I307-Y309 PolarHBondContact O-N 2.92Å; I307-I310 HydrophobicContact CD1-CD1 4.15Å; I307-I310 WeakPolarHBondContact O-CB 3.4Å; I307-I310 PolarHBondContact O-N 3.44Å; I307-I310 VanDerWaalsContact O-N 3.14Å; I307-V311 HydrophobicContact CG2-CG2 4.49Å; I307-V311 WeakPolarHBondContact O-CG2 3.21Å; I307-V311 PolarHBondContact O-N 3.04Å
308N89.3Confident87.8Confident45 Ų4530.4 Ų30.424%0.24115%0.153CC..Hα-helixtrans-60.6-43.4176.1-87.3-22.5000111.8V146 R150 E306 I310 V311 D312V146-N308 WeakPolarHBondContact CG1-ND2 3.42Å; R150-N308 WeakPolarHBondContact CD-OD1 3.19Å; R150-N308 PolarHBondContact NH1-O 2.99Å; E306-N308 PolarHBondContact O-N 3.18Å; N308-I310 VanDerWaalsContact C-N 3.32Å; N308-I310 PolarHBondContact O-N 3.4Å; N308-V311 PolarHBondContact O-N 3.39Å; N308-D312 PolarHBondContact O-N 2.93Å; N308-D312 VanDerWaalsContact O-OD2 3.13Å
309Y88.5Confident88.1Confident84 Ų8431.9 Ų31.933%0.32916%0.158SC..Hα-helixtrans-60.4-43.5173.8166.8-99.2000111.1E306 I307 V311 D312 R313 W606E306-Y309 PolarHBondContact O-N 3.36Å; I307-Y309 VanDerWaalsContact C-N 3.33Å; I307-Y309 PolarHBondContact O-N 2.92Å; Y309-V311 VanDerWaalsContact C-N 3.33Å; Y309-V311 PolarHBondContact O-N 3.49Å; Y309-D312 PolarHBondContact O-N 3.49Å; Y309-R313 HydrophobicContact CE1-CB 4.38Å; Y309-R313 HydrophobicContact CE2-CB 4.23Å; Y309-R313 WeakPolarHBondContact O-CB 3.11Å; Y309-R313 PolarHBondContact O-N 2.6Å; Y309-W606 AromaticContact CD1-CH2 3.43Å; Y309-W606 HydrophobicContact CD1-CH2 3.43Å; Y309-W606 VanDerWaalsContact CD1-CH2 3.43Å; Y309-W606 AromaticContact CD1-CZ2 3.59Å; Y309-W606 HydrophobicContact CD1-CZ2 3.59Å; Y309-W606 HydrophobicContact CD1-CZ3 4.27Å; Y309-W606 AromaticContact CE1-CH2 3.85Å; Y309-W606 HydrophobicContact CE1-CH2 3.85Å; Y309-W606 AromaticContact CE1-CZ2 3.94Å; Y309-W606 HydrophobicContact CE1-CZ2 3.94Å; Y309-W606 HydrophobicContact CE1-CZ3 4.32Å; Y309-W606 HydrophobicContact CG-CH2 4.5Å; Y309-W606 HydrophobicContact CG-CZ2 4.42Å
310I90Very high88.5Confident0 Ų031.4 Ų31.40%015%0.152CC..Hα-helixtrans-60.6-43.3178-65.9170.1000111.2L100 W102 E306 I307 N308 N314 W606L100-I310 HydrophobicContact CD1-CD1 3.75Å; L100-I310 HydrophobicContact CD2-CD1 4.24Å; L100-I310 HydrophobicContact CG-CD1 4.46Å; W102-I310 HydrophobicContact CH2-CD1 4.49Å; W102-I310 HydrophobicContact CH2-CG1 4.01Å; W102-I310 HydrophobicContact CZ2-CD1 4.24Å; W102-I310 HydrophobicContact CZ2-CG1 4.24Å; E306-I310 PolarHBondContact O-N 2.81Å; I307-I310 HydrophobicContact CD1-CD1 4.15Å; I307-I310 WeakPolarHBondContact O-CB 3.4Å; I307-I310 PolarHBondContact O-N 3.44Å; I307-I310 VanDerWaalsContact O-N 3.14Å; N308-I310 VanDerWaalsContact C-N 3.32Å; N308-I310 PolarHBondContact O-N 3.4Å; I310-N314 WeakPolarHBondContact O-CB 3.49Å; I310-N314 VanDerWaalsContact O-CG 3.23Å; I310-N314 PolarHBondContact O-N 2.87Å; I310-N314 PolarHBondContact O-ND2 2.77Å; I310-W606 HydrophobicContact CD1-CH2 4.38Å; I310-W606 HydrophobicContact CD1-CZ3 4.28Å; I310-W606 HydrophobicContact CG1-CH2 4.11Å; I310-W606 HydrophobicContact CG1-CZ3 4.21Å
311V90.1Very high89Confident4 Ų426.2 Ų26.22%0.02413%0.127CC..Hα-helixtrans-59.8-52.3175.6169.80000110.5V137 L140 F151 I307 N308 Y309 R313 N314 V315V137-V311 HydrophobicContact CG2-CG1 3.75Å; V137-V311 HydrophobicContact CG2-CG2 4.19Å; L140-V311 HydrophobicContact CD1-CG2 3.84Å; F151-V311 HydrophobicContact CE2-CG1 4.19Å; F151-V311 HydrophobicContact CZ-CG1 4.44Å; I307-V311 HydrophobicContact CG2-CG2 4.49Å; I307-V311 WeakPolarHBondContact O-CG2 3.21Å; I307-V311 PolarHBondContact O-N 3.04Å; N308-V311 PolarHBondContact O-N 3.39Å; Y309-V311 VanDerWaalsContact C-N 3.33Å; Y309-V311 PolarHBondContact O-N 3.49Å; V311-R313 PolarHBondContact O-N 3.05Å; V311-N314 PolarHBondContact O-N 3.44Å; V311-V315 WeakPolarHBondContact O-CG2 3.41Å; V311-V315 PolarHBondContact O-N 2.83Å
312D90.7Very high89.5Confident54 Ų5422 Ų2229%0.28911%0.105SC..Hα-helixtrans-60.5-49.7-178.7-73.7-37.8000112R150 N308 Y309 N314 V315 Q316R150-D312 IonicContact CZ-OD1 3.3Å; R150-D312 VanDerWaalsContact CZ-OD1 3.29Å; R150-D312 IonicContact CZ-OD2 3.88Å; R150-D312 IonicContact NH1-OD1 2.78Å; R150-D312 PolarHBondContact NH1-OD1 3.25Å; R150-D312 IonicContact NH1-OD2 3.17Å; R150-D312 PolarHBondContact NH1-OD2 3.13Å; R150-D312 IonicContact NH2-OD1 2.69Å; R150-D312 PolarHBondContact NH2-OD1 2.8Å; R150-D312 IonicContact NH2-OD2 2.72Å; N308-D312 PolarHBondContact O-N 2.93Å; N308-D312 VanDerWaalsContact O-OD2 3.13Å; Y309-D312 PolarHBondContact O-N 3.49Å; D312-N314 VanDerWaalsContact C-N 3.33Å; D312-N314 PolarHBondContact O-N 2.65Å; D312-V315 PolarHBondContact O-N 3.27Å; D312-Q316 WeakPolarHBondContact O-CB 3.47Å; D312-Q316 WeakPolarHBondContact O-CG 3.4Å; D312-Q316 PolarHBondContact O-N 2.97Å
313R90.8Very high89.9Confident15 Ų1521.8 Ų21.86%0.05710%0.104CC..Hα-helixtrans-59.5-45.2179-179-85.4-176.9-168.5-3.1110.7D104 Y309 V311 V317D104-R313 IonicContact OD1-CZ 3.72Å; D104-R313 IonicContact OD1-NH1 3.3Å; D104-R313 PolarHBondContact OD1-NH1 2.7Å; D104-R313 IonicContact OD1-NH2 2.9Å; D104-R313 PolarHBondContact OD1-NH2 3.46Å; D104-R313 IonicContact OD2-CZ 2.62Å; D104-R313 IonicContact OD2-NH1 2.65Å; D104-R313 IonicContact OD2-NH2 3.65Å; D104-R313 PolarHBondContact OD2-NH2 3.12Å; Y309-R313 HydrophobicContact CE1-CB 4.38Å; Y309-R313 HydrophobicContact CE2-CB 4.23Å; Y309-R313 WeakPolarHBondContact O-CB 3.11Å; Y309-R313 PolarHBondContact O-N 2.6Å; V311-R313 PolarHBondContact O-N 3.05Å; R313-V317 HydrophobicContact CG-CG2 4.22Å; R313-V317 VanDerWaalsContact O-CB 3.24Å; R313-V317 WeakPolarHBondContact O-CB 3.21Å; R313-V317 VanDerWaalsContact O-CG2 3.24Å; R313-V317 WeakPolarHBondContact O-CG2 3.23Å; R313-V317 PolarHBondContact O-N 2.8Å
314N93.9Very high90.1Very high2 Ų224.2 Ų24.21%0.01112%0.117CC..Hα-helixtrans-63.6-48.6-179.8-80.8-14000111P101 I103 N133 I310 V311 D312 Q316 S318P101-N314 PolarHBondContact O-ND2 3.01Å; I103-N314 HydrophobicContact CD1-CB 3.87Å; I103-N314 WeakPolarHBondContact CD1-O 3.49Å; I103-N314 HydrophobicContact CG1-CB 3.91Å; N133-N314 WeakPolarHBondContact OD1-CB 3.43Å; I310-N314 WeakPolarHBondContact O-CB 3.49Å; I310-N314 VanDerWaalsContact O-CG 3.23Å; I310-N314 PolarHBondContact O-N 2.87Å; I310-N314 PolarHBondContact O-ND2 2.77Å; V311-N314 PolarHBondContact O-N 3.44Å; D312-N314 VanDerWaalsContact C-N 3.33Å; D312-N314 PolarHBondContact O-N 2.65Å; N314-Q316 PolarHBondContact O-N 2.98Å; N314-S318 WeakPolarHBondContact O-CB 3.46Å; N314-S318 PolarHBondContact O-N 3.3Å; N314-S318 PolarHBondContact O-OG 3.47Å
315V92.7Very high90.1Very high27 Ų2724.2 Ų24.216%0.16412%0.116CC..Hα-helixtrans-59.1-49.6177.8174.20000110.7N133 V311 D312 S318 Y319N133-V315 HydrophobicContact CB-CG2 4.11Å; N133-V315 PolarHBondContact OD1-N 3.1Å; V311-V315 WeakPolarHBondContact O-CG2 3.41Å; V311-V315 PolarHBondContact O-N 2.83Å; D312-V315 PolarHBondContact O-N 3.27Å; V315-S318 PolarHBondContact O-N 3.15Å; V315-S318 PolarHBondContact O-OG 3.42Å; V315-Y319 HydrophobicContact CG1-CD2 3.92Å; V315-Y319 HydrophobicContact CG1-CE2 3.6Å; V315-Y319 WeakPolarHBondContact O-CD2 3.41Å; V315-Y319 PolarHBondContact O-N 3.46Å
316Q90.7Very high90.1Very high68 Ų6825.2 Ų25.232%0.31812%0.12SC..Hα-helixtrans-60.2-57.3179.4-69.9170.425.900111.7D312 N314 S318 Y319 L320 V555D312-Q316 WeakPolarHBondContact O-CB 3.47Å; D312-Q316 WeakPolarHBondContact O-CG 3.4Å; D312-Q316 PolarHBondContact O-N 2.97Å; N314-Q316 PolarHBondContact O-N 2.98Å; Q316-S318 PolarHBondContact O-N 3.38Å; Q316-Y319 PolarHBondContact O-N 2.88Å; Q316-L320 VanDerWaalsContact O-CG 3.29Å; Q316-L320 WeakPolarHBondContact O-CG 3.35Å; Q316-L320 PolarHBondContact O-N 2.81Å; Q316-V555 HydrophobicContact CB-CG2 4.42Å
317V88.9Confident89.9Confident1 Ų125.4 Ų25.41%0.00613%0.134CC..Hα-helixtrans-59.6-34.5-178.7173.10000111.5D104 R313 L320 M321 V555 W559D104-V317 HydrophobicContact CB-CG1 4.17Å; R313-V317 HydrophobicContact CG-CG2 4.22Å; R313-V317 VanDerWaalsContact O-CB 3.24Å; R313-V317 WeakPolarHBondContact O-CB 3.21Å; R313-V317 VanDerWaalsContact O-CG2 3.24Å; R313-V317 WeakPolarHBondContact O-CG2 3.23Å; R313-V317 PolarHBondContact O-N 2.8Å; V317-L320 PolarHBondContact O-N 3.1Å; V317-M321 HydrophobicContact CG1-CE 3.72Å; V317-M321 HydrophobicContact CG1-CG 4.26Å; V317-M321 HydrophobicContact CG1-SD 3.8Å; V317-M321 WeakPolarHBondContact O-CB 3.37Å; V317-M321 VanDerWaalsContact O-CG 3.31Å; V317-M321 WeakPolarHBondContact O-CG 3.34Å; V317-M321 PolarHBondContact O-N 2.92Å; V317-V555 HydrophobicContact CG2-CG1 3.87Å; V317-W559 HydrophobicContact CG1-CZ2 4.21Å
318S94Very high89.8Confident0 Ų031.2 Ų31.20%016%0.159CC..Hα-helixtrans-63.5-48.9177.672.10000113.2N133 N314 V315 Q316 L320 M321 V322N133-S318 PolarHBondContact ND2-OG 3.34Å; N314-S318 WeakPolarHBondContact O-CB 3.46Å; N314-S318 PolarHBondContact O-N 3.3Å; N314-S318 PolarHBondContact O-OG 3.47Å; V315-S318 PolarHBondContact O-N 3.15Å; V315-S318 PolarHBondContact O-OG 3.42Å; Q316-S318 PolarHBondContact O-N 3.38Å; S318-L320 VanDerWaalsContact C-N 3.34Å; S318-M321 PolarHBondContact O-N 3.36Å; S318-V322 WeakPolarHBondContact O-CG1 3.49Å; S318-V322 VanDerWaalsContact O-CG2 3.25Å; S318-V322 WeakPolarHBondContact O-CG2 3.5Å; S318-V322 PolarHBondContact O-N 3.41Å; S318-V322 VanDerWaalsContact O-N 3.1Å
319Y93.6Very high89.6Confident44 Ų4431 Ų3117%0.17316%0.158CC..Hα-helixtrans-67.8-36.7178.3-68.6-46.1000111.7R126 A129 R130 V315 Q316 M321 D323R126-Y319 HydrophobicContact CB-CE1 4.34Å; R126-Y319 HydrophobicContact CG-CD1 4.38Å; A129-Y319 HydrophobicContact CB-CE1 4.39Å; R130-Y319 WeakPolarHBondContact CD-OH 3.47Å; V315-Y319 HydrophobicContact CG1-CD2 3.92Å; V315-Y319 HydrophobicContact CG1-CE2 3.6Å; V315-Y319 WeakPolarHBondContact O-CD2 3.41Å; V315-Y319 PolarHBondContact O-N 3.46Å; Q316-Y319 PolarHBondContact O-N 2.88Å; Y319-M321 PolarHBondContact O-N 2.95Å; Y319-D323 WeakPolarHBondContact O-CA 3.34Å; Y319-D323 WeakPolarHBondContact O-CB 3.2Å; Y319-D323 PolarHBondContact O-N 2.96Å
320L90.3Very high89.5Confident7 Ų727.2 Ų27.24%0.03714%0.143CC..Iπ-helixtrans-56.4-50.7172.8-69178.6000112Q316 V317 S318 D324 Y325 Y551 V555 W559Q316-L320 VanDerWaalsContact O-CG 3.29Å; Q316-L320 WeakPolarHBondContact O-CG 3.35Å; Q316-L320 PolarHBondContact O-N 2.81Å; V317-L320 PolarHBondContact O-N 3.1Å; S318-L320 VanDerWaalsContact C-N 3.34Å; L320-D324 HydrophobicContact CD2-CB 4.17Å; L320-D324 VanDerWaalsContact CD2-OD2 3.27Å; L320-D324 WeakPolarHBondContact CD2-OD2 3.23Å; L320-D324 PolarHBondContact O-N 3.39Å; L320-Y325 HydrophobicContact CB-CD2 4.04Å; L320-Y325 HydrophobicContact CB-CE2 4.16Å; L320-Y325 HydrophobicContact CD2-CE2 4.31Å; L320-Y325 VanDerWaalsContact O-CD2 3.31Å; L320-Y325 WeakPolarHBondContact O-CD2 3.42Å; L320-Y325 PolarHBondContact O-N 3.41Å; L320-Y551 HydrophobicContact CD2-CE1 3.63Å; L320-Y551 HydrophobicContact CD2-CE2 3.97Å; L320-Y551 WeakPolarHBondContact CD2-OH 3.45Å; L320-V555 HydrophobicContact CD1-CG1 3.97Å; L320-V555 HydrophobicContact CD1-CG2 4.17Å; L320-W559 HydrophobicContact CB-CH2 3.93Å; L320-W559 HydrophobicContact CB-CZ2 4.26Å; L320-W559 HydrophobicContact CD1-CH2 4.38Å; L320-W559 HydrophobicContact CD1-CZ2 3.97Å
321M91.6Very high89.3Confident0 Ų032.6 Ų32.60%018%0.176CC..Iπ-helixtrans-67-42.3-176.1-73.8177.2165.800112.9D104 M107 I108 V317 S318 Y319 W559D104-M321 HydrophobicContact CB-CE 3.5Å; D104-M321 VanDerWaalsContact CB-CE 3.5Å; D104-M321 HydrophobicContact CB-SD 3.64Å; M107-M321 HydrophobicContact CB-CB 4.03Å; M107-M321 HydrophobicContact CB-SD 3.83Å; I108-M321 HydrophobicContact CD1-CE 4.05Å; I108-M321 HydrophobicContact CD1-SD 4.45Å; I108-M321 HydrophobicContact CG1-CE 3.92Å; I108-M321 HydrophobicContact CG1-SD 3.75Å; V317-M321 HydrophobicContact CG1-CE 3.72Å; V317-M321 HydrophobicContact CG1-CG 4.26Å; V317-M321 HydrophobicContact CG1-SD 3.8Å; V317-M321 WeakPolarHBondContact O-CB 3.37Å; V317-M321 VanDerWaalsContact O-CG 3.31Å; V317-M321 WeakPolarHBondContact O-CG 3.34Å; V317-M321 PolarHBondContact O-N 2.92Å; S318-M321 PolarHBondContact O-N 3.36Å; Y319-M321 PolarHBondContact O-N 2.95Å; M321-W559 HydrophobicContact CE-CB 4.14Å; M321-W559 HydrophobicContact CE-CD2 3.41Å; M321-W559 VanDerWaalsContact CE-CD2 3.41Å; M321-W559 HydrophobicContact CE-CE3 3.2Å; M321-W559 HydrophobicContact CE-CG 3.83Å; M321-W559 HydrophobicContact CE-CH2 4.43Å; M321-W559 HydrophobicContact CE-CZ3 3.77Å; M321-W559 HydrophobicContact CG-CE3 4.13Å; M321-W559 HydrophobicContact CG-CH2 4.01Å; M321-W559 HydrophobicContact CG-CZ3 3.68Å
322V92.5Very high89Confident0 Ų033.7 Ų33.70%018%0.182CC..Iπ-helixtrans-90-14.1-171.8-52.40000114.3M107 A110 A111 R125 R126 A129 S318M107-V322 HydrophobicContact CB-CG1 4.01Å; M107-V322 HydrophobicContact SD-CG1 3.96Å; A110-V322 HydrophobicContact CB-CG1 4.29Å; A111-V322 HydrophobicContact CB-CG1 4.49Å; R125-V322 HydrophobicContact CB-CB 4.07Å; R125-V322 HydrophobicContact CB-CG2 4.37Å; R125-V322 WeakPolarHBondContact CD-O 3.37Å; R125-V322 PolarHBondContact NE-O 3.42Å; R126-V322 HydrophobicContact CG-CG2 4.4Å; A129-V322 HydrophobicContact CB-CG1 4.48Å; A129-V322 HydrophobicContact CB-CG2 4.11Å; S318-V322 WeakPolarHBondContact O-CG1 3.49Å; S318-V322 VanDerWaalsContact O-CG2 3.25Å; S318-V322 WeakPolarHBondContact O-CG2 3.5Å; S318-V322 PolarHBondContact O-N 3.41Å; S318-V322 VanDerWaalsContact O-N 3.1Å
323D90Very high88.6Confident30 Ų3032.8 Ų32.816%0.1619%0.185CC..Iπ-helixtrans-121.1-75.9-178.6-1576000109.9R122 R126 Y319 Y325 Y326R122-D323 WeakPolarHBondContact CD-OD1 3.41Å; R122-D323 IonicContact CZ-OD1 3.38Å; R122-D323 IonicContact CZ-OD2 2.73Å; R122-D323 VanDerWaalsContact CZ-OD2 3.31Å; R122-D323 VanDerWaalsContact NE-CG 3.3Å; R122-D323 IonicContact NE-OD1 3.25Å; R122-D323 PolarHBondContact NE-OD1 2.88Å; R122-D323 IonicContact NE-OD2 3.23Å; R122-D323 PolarHBondContact NE-OD2 3.43Å; R122-D323 IonicContact NH2-OD2 2.75Å; R122-D323 PolarHBondContact NH2-OD2 3.37Å; R126-D323 WeakPolarHBondContact CD-OD2 3.37Å; R126-D323 IonicContact CZ-OD2 2.59Å; R126-D323 IonicContact NE-OD2 3.72Å; R126-D323 IonicContact NH1-OD2 3.25Å; R126-D323 PolarHBondContact NH1-OD2 3.28Å; Y319-D323 WeakPolarHBondContact O-CA 3.34Å; Y319-D323 WeakPolarHBondContact O-CB 3.2Å; Y319-D323 PolarHBondContact O-N 2.96Å; D323-Y325 VanDerWaalsContact C-N 3.28Å; D323-Y325 PolarHBondContact O-N 3.36Å; D323-Y325 VanDerWaalsContact O-N 3.15Å; D323-Y326 WeakPolarHBondContact O-CB 3.44Å; D323-Y326 PolarHBondContact O-N 3.34Å; D323-Y326 VanDerWaalsContact O-N 3.15Å
324D86.5Confident88.5Confident60 Ų6038.2 Ų38.232%0.32121%0.206SC..Iπ-helixtrans-62.8-31.2-169.2-66-2.1000113.5L320 K328 Y551L320-D324 HydrophobicContact CD2-CB 4.17Å; L320-D324 VanDerWaalsContact CD2-OD2 3.27Å; L320-D324 WeakPolarHBondContact CD2-OD2 3.23Å; L320-D324 PolarHBondContact O-N 3.39Å; D324-K328 VanDerWaalsContact O-CD 3.22Å; D324-K328 WeakPolarHBondContact O-CD 3.29Å; D324-K328 WeakPolarHBondContact O-CE 3.41Å; D324-K328 PolarHBondContact O-NZ 3.31Å; D324-Y551 PolarHBondContact OD2-OH 3.47Å
325Y84.2Confident88.1Confident8 Ų838.4 Ų38.43%0.03121%0.207CC..THydrogen-bonded Turntrans-111.28.5179.9-65.7-70.9000114.4L320 D323 G327 K328 K547 W559 L560 N567L320-Y325 HydrophobicContact CB-CD2 4.04Å; L320-Y325 HydrophobicContact CB-CE2 4.16Å; L320-Y325 HydrophobicContact CD2-CE2 4.31Å; L320-Y325 VanDerWaalsContact O-CD2 3.31Å; L320-Y325 WeakPolarHBondContact O-CD2 3.42Å; L320-Y325 PolarHBondContact O-N 3.41Å; D323-Y325 VanDerWaalsContact C-N 3.28Å; D323-Y325 PolarHBondContact O-N 3.36Å; D323-Y325 VanDerWaalsContact O-N 3.15Å; Y325-G327 PolarHBondContact O-N 3.39Å; Y325-G327 VanDerWaalsContact O-N 3.09Å; Y325-K328 PolarHBondContact O-N 2.64Å; Y325-K547 HydrophobicContact CE1-CG 4.4Å; Y325-K547 WeakPolarHBondContact OH-CB 3.25Å; Y325-K547 VanDerWaalsContact OH-CG 3.25Å; Y325-K547 WeakPolarHBondContact OH-CG 3.38Å; Y325-W559 AromaticContact CD2-CH2 3.7Å; Y325-W559 HydrophobicContact CD2-CH2 3.7Å; Y325-W559 HydrophobicContact CD2-CZ3 4.09Å; Y325-W559 AromaticContact CE2-CH2 3.75Å; Y325-W559 HydrophobicContact CE2-CH2 3.75Å; Y325-W559 HydrophobicContact CE2-CZ3 4.42Å; Y325-L560 HydrophobicContact CD1-CD1 3.61Å; Y325-L560 HydrophobicContact CD2-CD1 4.28Å; Y325-L560 HydrophobicContact CE1-CD1 3.43Å; Y325-L560 VanDerWaalsContact CE1-CD1 3.43Å; Y325-L560 HydrophobicContact CE1-CD2 4.2Å; Y325-L560 HydrophobicContact CE1-CG 4.48Å; Y325-L560 HydrophobicContact CE2-CD1 4.14Å; Y325-L560 HydrophobicContact CG-CD1 4.03Å; Y325-N567 PolarHBondContact O-ND2 2.77Å
326Y89Confident87.8Confident31 Ų3143.1 Ų43.112%0.12223%0.225CC..THydrogen-bonded Turntrans-60.3117.4176.8172.9-107000110.6A111 H115 G116 L117 D323 K328A111-Y326 HydrophobicContact CB-CD2 4.33Å; A111-Y326 VanDerWaalsContact O-CD2 3.26Å; A111-Y326 WeakPolarHBondContact O-CD2 3.35Å; A111-Y326 WeakPolarHBondContact O-CE2 3.5Å; H115-Y326 WeakPolarHBondContact CA-OH 3.5Å; G116-Y326 PolarHBondContact N-OH 3.13Å; L117-Y326 HydrophobicContact CD2-CD1 4.02Å; L117-Y326 HydrophobicContact CD2-CE1 3.67Å; L117-Y326 HydrophobicContact CG-CE1 4.36Å; D323-Y326 WeakPolarHBondContact O-CB 3.44Å; D323-Y326 PolarHBondContact O-N 3.34Å; D323-Y326 VanDerWaalsContact O-N 3.15Å; Y326-K328 PolarHBondContact O-N 3.29Å; Y326-K328 VanDerWaalsContact O-N 3.09Å
327G82.6Confident87.6Confident51 Ų5140 Ų4053%0.52621%0.211SC..THydrogen-bonded Turntrans69.50.1176.300000116.5Y325Y325-G327 PolarHBondContact O-N 3.39Å; Y325-G327 VanDerWaalsContact O-N 3.09Å
328K85.6Confident87.4Confident124 Ų12440.4 Ų40.454%0.53921%0.212SC..  trans-84.3131.9-178-61.5-173.8-171.2164.30111.8D324 Y325 Y326 N567D324-K328 VanDerWaalsContact O-CD 3.22Å; D324-K328 WeakPolarHBondContact O-CD 3.29Å; D324-K328 WeakPolarHBondContact O-CE 3.41Å; D324-K328 PolarHBondContact O-NZ 3.31Å; Y325-K328 PolarHBondContact O-N 2.64Å; Y326-K328 PolarHBondContact O-N 3.29Å; Y326-K328 VanDerWaalsContact O-N 3.09Å; K328-N567 PolarHBondContact N-ND2 3.03Å; K328-N567 PolarHBondContact O-ND2 3.18Å
329I85.8Confident87Confident42 Ų4248.2 Ų48.222%0.21525%0.246CC..  trans-133.6148.2171.155.5173000110.2L332 W564 N567 L568 K571I329-L332 HydrophobicContact CD1-CD1 4.46Å; I329-W564 WeakPolarHBondContact CG2-O 3.42Å; I329-N567 HydrophobicContact CG2-CB 3.33Å; I329-L568 HydrophobicContact CD1-CD1 4.15Å; I329-L568 HydrophobicContact CG2-CB 4.35Å; I329-K571 HydrophobicContact CD1-CD 3.38Å
330P86.4Confident86.3Confident3 Ų349.9 Ų49.92%0.01926%0.256CS..PPolyproline II helixtrans-58.8158.2167.1-24.135.5000112.4L332 E540 I543 W564P330-L332 PolarHBondContact O-N 3.04Å; P330-E540 HydrophobicContact CB-CG 3.55Å; P330-E540 HydrophobicContact CG-CG 3.89Å; P330-I543 HydrophobicContact CB-CD1 3.87Å; P330-I543 HydrophobicContact CG-CD1 4.19Å; P330-W564 HydrophobicContact CG-CD2 3.59Å; P330-W564 HydrophobicContact CG-CE3 3.8Å; P330-W564 HydrophobicContact CG-CG 4.05Å; P330-W564 HydrophobicContact CG-CH2 4.16Å; P330-W564 HydrophobicContact CG-CZ2 3.97Å; P330-W564 HydrophobicContact CG-CZ3 4.09Å
331T85Confident85.2Confident113 Ų11356.1 Ų56.169%0.69329%0.285SS*.PPolyproline II helixtrans-62125.3175.5-52.80000110.2
332L84.7Confident84.1Confident28 Ų2859.6 Ų59.615%0.14731%0.305CS..PPolyproline II helixtrans-76.1131.7178.9-65.3168.6000110.4I329 P330 R493 M496 T500 L568I329-L332 HydrophobicContact CD1-CD1 4.46Å; P330-L332 PolarHBondContact O-N 3.04Å; L332-R493 VanDerWaalsContact CD1-CZ 3.47Å; L332-M496 HydrophobicContact CB-CG 4.37Å; L332-M496 HydrophobicContact CB-SD 3.71Å; L332-T500 HydrophobicContact CD2-CG2 3.79Å; L332-L568 HydrophobicContact CD1-CD1 3.65Å; L332-L568 HydrophobicContact CD2-CD1 3.98Å; L332-L568 HydrophobicContact CD2-CD2 4.01Å; L332-L568 HydrophobicContact CG-CD1 4.37Å
333G82.4Confident83Confident34 Ų3459.6 Ų59.635%0.35131%0.306SS..  trans-150.8174.8176.600000111.4D335G333-D335 PolarHBondContact O-N 3.36Å
334R87.8Confident82.3Confident129 Ų12961 Ų6149%0.48732%0.315SS..  trans-64.3129.5175.1-64.2-179.3176.9172.1-0.9109.4W338 E492 M496R334-W338 HydrophobicContact CB-CB 4.17Å; R334-W338 HydrophobicContact CB-CD2 3.82Å; R334-W338 HydrophobicContact CB-CE3 4.03Å; R334-W338 HydrophobicContact CB-CG 3.88Å; R334-W338 HydrophobicContact CG-CD2 3.75Å; R334-W338 HydrophobicContact CG-CE3 4.24Å; R334-W338 HydrophobicContact CG-CG 3.97Å; R334-W338 HydrophobicContact CG-CZ2 4.26Å; R334-E492 IonicContact CZ-OE1 3.64Å; R334-E492 IonicContact CZ-OE2 3.73Å; R334-E492 IonicContact NE-OE1 3.75Å; R334-E492 PolarHBondContact NE-OE1 2.97Å; R334-E492 IonicContact NH2-OE1 2.7Å; R334-E492 PolarHBondContact NH2-OE1 3.48Å; R334-E492 IonicContact NH2-OE2 2.82Å; R334-E492 PolarHBondContact NH2-OE2 2.96Å; R334-M496 HydrophobicContact CG-CE 4.37Å
335D85.9Confident82Confident7 Ų758.2 Ų58.24%0.03730%0.3CS..  trans-75.5167.8173.770.786.7000111.7G333 H337 W338 R499G333-D335 PolarHBondContact O-N 3.36Å; D335-H337 PolarHBondContact O-N 3.01Å; D335-H337 VanDerWaalsContact O-N 3.15Å; D335-H337 WeakPolarHBondContact OD1-CA 3.45Å; D335-H337 WeakPolarHBondContact OD1-CB 3.44Å; D335-H337 PolarHBondContact OD1-N 3.12Å; D335-W338 VanDerWaalsContact O-CB 3.31Å; D335-W338 WeakPolarHBondContact O-CB 3.23Å; D335-W338 PolarHBondContact O-N 3.5Å; D335-W338 PolarHBondContact OD1-N 3.28Å; D335-R499 IonicContact OD1-CZ 3.77Å; D335-R499 IonicContact OD1-NH2 3.15Å; D335-R499 PolarHBondContact OD1-NH2 3.39Å; D335-R499 IonicContact OD2-CZ 2.77Å; D335-R499 VanDerWaalsContact OD2-CZ 3.25Å; D335-R499 IonicContact OD2-NE 2.86Å; D335-R499 PolarHBondContact OD2-NE 3.03Å; D335-R499 IonicContact OD2-NH2 3.41Å; D335-R499 PolarHBondContact OD2-NH2 3.38Å
336K87Confident81.8Confident125 Ų12561 Ų6154%0.54332%0.319SS..THydrogen-bonded Turntrans-57.8-31.6-177-176.8168.3-176.8166.30113.7W338 H532K336-W338 VanDerWaalsContact C-N 3.34Å; K336-H532 WeakPolarHBondContact CD-O 3.46Å; K336-H532 WeakPolarHBondContact CE-O 3.32Å; K336-H532 PolarHBondContact NZ-O 2.6Å
337H85.3Confident81.2Confident4 Ų461.1 Ų61.12%0.01932%0.321CS..THydrogen-bonded Turntrans-98.122-175.4-60.2-68.7000112.7D335 F339 E340 T343 R499 S533 Y692D335-H337 PolarHBondContact O-N 3.01Å; D335-H337 VanDerWaalsContact O-N 3.15Å; D335-H337 WeakPolarHBondContact OD1-CA 3.45Å; D335-H337 WeakPolarHBondContact OD1-CB 3.44Å; D335-H337 PolarHBondContact OD1-N 3.12Å; H337-F339 PolarHBondContact O-N 3.24Å; H337-F339 VanDerWaalsContact O-N 3.09Å; H337-E340 HydrophobicContact CB-CB 4.41Å; H337-E340 IonicContact CE1-OE2 2.61Å; H337-E340 IonicContact CG-OE2 2.67Å; H337-E340 VanDerWaalsContact ND1-CD 3.28Å; H337-E340 IonicContact ND1-OE1 3.44Å; H337-E340 PolarHBondContact ND1-OE1 3.35Å; H337-E340 IonicContact ND1-OE2 2.98Å; H337-E340 PolarHBondContact ND1-OE2 2.9Å; H337-E340 PolarHBondContact O-N 2.98Å; H337-E340 VanDerWaalsContact O-N 3.12Å; H337-T343 HydrophobicContact CB-CG2 3.41Å; H337-T343 VanDerWaalsContact CB-CG2 3.41Å; H337-R499 VanDerWaalsContact C-NH2 3.29Å; H337-R499 PolarHBondContact O-NH2 3.3Å; H337-S533 PolarHBondContact NE2-O 3.49Å; H337-S533 VanDerWaalsContact NE2-O 3.11Å; H337-Y692 HydrophobicContact CB-CE2 4.16Å
338W85.4Confident80.6Confident8 Ų860 Ų603%0.0330%0.304CS..THydrogen-bonded Turntrans-56.9-29.3-171.9-166.6-103000114.7R334 D335 K336 E492 R495 M496R334-W338 HydrophobicContact CB-CB 4.17Å; R334-W338 HydrophobicContact CB-CD2 3.82Å; R334-W338 HydrophobicContact CB-CE3 4.03Å; R334-W338 HydrophobicContact CB-CG 3.88Å; R334-W338 HydrophobicContact CG-CD2 3.75Å; R334-W338 HydrophobicContact CG-CE3 4.24Å; R334-W338 HydrophobicContact CG-CG 3.97Å; R334-W338 HydrophobicContact CG-CZ2 4.26Å; D335-W338 VanDerWaalsContact O-CB 3.31Å; D335-W338 WeakPolarHBondContact O-CB 3.23Å; D335-W338 PolarHBondContact O-N 3.5Å; D335-W338 PolarHBondContact OD1-N 3.28Å; K336-W338 VanDerWaalsContact C-N 3.34Å; W338-E492 HydrophobicContact CH2-CG 4.49Å; W338-E492 HydrophobicContact CZ2-CG 3.72Å; W338-R495 HydrophobicContact CH2-CB 4.25Å; W338-R495 HydrophobicContact CH2-CG 3.94Å; W338-R495 HydrophobicContact CZ2-CG 4.2Å; W338-R495 PolarHBondContact O-NH1 3.2Å; W338-R495 PolarHBondContact O-NH2 3.41Å; W338-M496 HydrophobicContact CH2-CB 3.78Å; W338-M496 HydrophobicContact CH2-CE 4.46Å; W338-M496 HydrophobicContact CH2-CG 4.35Å; W338-M496 HydrophobicContact CZ3-CB 4.28Å; W338-M496 HydrophobicContact CZ3-CG 4.46Å
339F85.4Confident79.9Confident165 Ų16560.8 Ų60.872%0.72432%0.319SS*.THydrogen-bonded Turntrans-109.86.9-177.3-56.7-70.6000113.4H337H337-F339 PolarHBondContact O-N 3.24Å; H337-F339 VanDerWaalsContact O-N 3.09Å
340E78.1Confident78.7Confident79 Ų7962.1 Ų62.137%0.36934%0.336SS..  trans-95.9124.8178.8-66.5176.5-15900110.5H337 T343H337-E340 HydrophobicContact CB-CB 4.41Å; H337-E340 IonicContact CE1-OE2 2.61Å; H337-E340 IonicContact CG-OE2 2.67Å; H337-E340 VanDerWaalsContact ND1-CD 3.28Å; H337-E340 IonicContact ND1-OE1 3.44Å; H337-E340 PolarHBondContact ND1-OE1 3.35Å; H337-E340 IonicContact ND1-OE2 2.98Å; H337-E340 PolarHBondContact ND1-OE2 2.9Å; H337-E340 PolarHBondContact O-N 2.98Å; H337-E340 VanDerWaalsContact O-N 3.12Å; E340-T343 HydrophobicContact CB-CG2 4.25Å; E340-T343 WeakPolarHBondContact OE2-CA 3.28Å
341E68.2Low77.8Confident138 Ų13862 Ų6265%0.64534%0.335SS*.SBendtrans-70.3-41173.5-67.6174.4-174.400111.5L693E341-L693 WeakPolarHBondContact O-CD2 3.48Å
342V67.9Low77.2Confident72 Ų7261.2 Ų61.244%0.43633%0.325SS..SBendtrans-127.6110176.4-178.80000109.4
343T70.7Confident76.3Confident1 Ų162.1 Ų62.11%0.00634%0.341CS..  trans-72.6137.1-174.958.20000112.3H337 E340 Q689 Y692H337-T343 HydrophobicContact CB-CG2 3.41Å; H337-T343 VanDerWaalsContact CB-CG2 3.41Å; E340-T343 HydrophobicContact CB-CG2 4.25Å; E340-T343 WeakPolarHBondContact OE2-CA 3.28Å; T343-Q689 VanDerWaalsContact O-CG 3.26Å; T343-Q689 WeakPolarHBondContact O-CG 3.47Å; T343-Q689 PolarHBondContact O-NE2 3.41Å; T343-Q689 WeakPolarHBondContact OG1-CG 3.36Å; T343-Y692 HydrophobicContact CG2-CD2 3.49Å; T343-Y692 VanDerWaalsContact CG2-CD2 3.49Å; T343-Y692 HydrophobicContact CG2-CE2 3.92Å
344T74Confident75.7Confident59 Ų5961.2 Ų61.236%0.36233%0.328SS..  trans-120.3107.8173.8-57.50000109.6R727T344-R727 PolarHBondContact OG1-NH1 2.82Å; T344-R727 VanDerWaalsContact OG1-NH1 3.1Å; T344-R727 PolarHBondContact OG1-NH2 3.33Å
345I80.5Confident74.9Confident1 Ų159.5 Ų59.51%0.00532%0.324CS..  trans-80.6131.2-178.7-60.8155.3000109.5R523 F524 S533 F535 D685 L688I345-R523 VanDerWaalsContact CB-NH2 3.28Å; I345-R523 PolarHBondContact O-NH2 2.88Å; I345-F524 HydrophobicContact CG2-CE1 4.13Å; I345-F524 HydrophobicContact CG2-CZ 4.1Å; I345-S533 WeakPolarHBondContact CG2-OG 3.28Å; I345-F535 HydrophobicContact CD1-CE2 3.77Å; I345-F535 HydrophobicContact CD1-CZ 3.59Å; I345-F535 HydrophobicContact CG1-CE2 4.22Å; I345-F535 HydrophobicContact CG1-CZ 4.46Å; I345-F535 HydrophobicContact CG2-CE2 4.03Å; I345-D685 WeakPolarHBondContact CD1-OD1 3.37Å; I345-L688 HydrophobicContact CD1-CB 4.18Å; I345-L688 HydrophobicContact CD1-CD2 3.7Å; I345-L688 HydrophobicContact CG1-CD2 4.01Å
346P80.2Confident73.9Confident66 Ų6660.7 Ų60.743%0.42933%0.328SS..  trans-65.1160.9-179.625.6-33.5000113.2R523P346-R523 PolarHBondContact O-NE 3.1Å; P346-R523 PolarHBondContact O-NH2 3.32Å
347H75.5Confident72.9Confident35 Ų3561 Ų6116%0.16233%0.329CS..  trans-119.1143.8171.4-81.4-101.8000109.2S351 M352 R523H347-S351 WeakPolarHBondContact CB-OG 3.18Å; H347-S351 PolarHBondContact ND1-O 2.82Å; H347-S351 VanDerWaalsContact ND1-O 3.16Å; H347-S351 PolarHBondContact ND1-OG 2.65Å; H347-M352 HydrophobicContact CB-SD 4.3Å; H347-R523 PolarHBondContact CE1-NE 3.21Å; H347-R523 PolarHBondContact NE2-NH2 2.94Å
348T69.9Low71.7Confident27 Ų2764.6 Ų64.617%0.16635%0.353CS..  trans-68.5161.7164.158.30000110.7A350 S351 M352 K522 R523 P525 H529T348-A350 VanDerWaalsContact C-N 3.25Å; T348-A350 PolarHBondContact O-N 3.28Å; T348-S351 PolarHBondContact N-OG 3.08Å; T348-S351 CarbonylContact O-C 3.6Å; T348-S351 PolarHBondContact O-N 3.24Å; T348-S351 PolarHBondContact O-OG 2.73Å; T348-S351 VanDerWaalsContact O-OG 3.13Å; T348-S351 WeakPolarHBondContact OG1-CB 3.15Å; T348-S351 PolarHBondContact OG1-N 3.16Å; T348-S351 PolarHBondContact OG1-OG 3.47Å; T348-M352 PolarHBondContact O-N 3.31Å; T348-K522 PolarHBondContact OG1-O 3.21Å; T348-R523 VanDerWaalsContact CG2-O 3.28Å; T348-R523 WeakPolarHBondContact CG2-O 3.33Å; T348-P525 HydrophobicContact CG2-CG 4.41Å; T348-H529 VanDerWaalsContact CG2-CD2 3.44Å; T348-H529 WeakPolarHBondContact CG2-CD2 3.45Å; T348-H529 WeakPolarHBondContact CG2-NE2 3.31Å
349V71.7Confident70.5Confident141 Ų14169 Ų6986%0.85537%0.372SS*.G310 helixtrans-53.9-44.7173.2-179.50000111.1S351 M352V349-S351 VanDerWaalsContact C-N 3.27Å; V349-S351 PolarHBondContact O-N 2.67Å; V349-M352 WeakPolarHBondContact O-CB 3.31Å; V349-M352 PolarHBondContact O-N 2.99Å
350A60.4Low69.1Low69 Ų6962.6 Ų62.657%0.5735%0.35SS*.G310 helixtrans-64.6-27178.900000113.9T348 K522T348-A350 VanDerWaalsContact C-N 3.25Å; T348-A350 PolarHBondContact O-N 3.28Å; A350-K522 HydrophobicContact CB-CB 4.44Å
351S68.5Low67.9Low0 Ų059.6 Ų59.60%034%0.337CS..G310 helixtrans-100.4-1.4179.266.70000113.9H347 T348 V349 G353 L354 K355 R523H347-S351 WeakPolarHBondContact CB-OG 3.18Å; H347-S351 PolarHBondContact ND1-O 2.82Å; H347-S351 VanDerWaalsContact ND1-O 3.16Å; H347-S351 PolarHBondContact ND1-OG 2.65Å; T348-S351 PolarHBondContact N-OG 3.08Å; T348-S351 CarbonylContact O-C 3.6Å; T348-S351 PolarHBondContact O-N 3.24Å; T348-S351 PolarHBondContact O-OG 2.73Å; T348-S351 VanDerWaalsContact O-OG 3.13Å; T348-S351 WeakPolarHBondContact OG1-CB 3.15Å; T348-S351 PolarHBondContact OG1-N 3.16Å; T348-S351 PolarHBondContact OG1-OG 3.47Å; V349-S351 VanDerWaalsContact C-N 3.27Å; V349-S351 PolarHBondContact O-N 2.67Å; S351-G353 VanDerWaalsContact C-N 3.28Å; S351-G353 PolarHBondContact O-N 3.43Å; S351-L354 CarbonylContact O-C 3.54Å; S351-L354 WeakPolarHBondContact O-CA 3.37Å; S351-L354 WeakPolarHBondContact O-CB 3.43Å; S351-L354 PolarHBondContact O-N 3.16Å; S351-K355 PolarHBondContact O-N 3.17Å; S351-R523 WeakPolarHBondContact OG-CA 3.48Å
352M71.3Confident67.1Low98 Ų9854.6 Ų54.648%0.48332%0.318SS..G310 helixtrans-61.8-37.4-176.9-167.465.7-104.500111.8H347 T348 V349 L354 K355H347-M352 HydrophobicContact CB-SD 4.3Å; T348-M352 PolarHBondContact O-N 3.31Å; V349-M352 WeakPolarHBondContact O-CB 3.31Å; V349-M352 PolarHBondContact O-N 2.99Å; M352-L354 PolarHBondContact O-N 3.42Å; M352-K355 HydrophobicContact CE-CB 3.71Å; M352-K355 HydrophobicContact CE-CD 3.35Å; M352-K355 HydrophobicContact CE-CG 4.16Å; M352-K355 WeakPolarHBondContact O-CB 3.44Å; M352-K355 PolarHBondContact O-N 3.02Å
353G66.9Low66.3Low46 Ų4652.7 Ų52.747%0.47431%0.306SS..G310 helixtrans-70.2-15.1173.400000114.6S351 R356S351-G353 VanDerWaalsContact C-N 3.28Å; S351-G353 PolarHBondContact O-N 3.43Å; G353-R356 PolarHBondContact O-NH1 3.22Å; G353-R356 PolarHBondContact O-NH2 3.29Å
354L69.5Low65.5Low15 Ų1554.8 Ų54.88%0.07932%0.324CS..G310 helixtrans-95.5-4.3177.1-56.1174000112.4S351 M352 R356 M374 A519 K522S351-L354 CarbonylContact O-C 3.54Å; S351-L354 WeakPolarHBondContact O-CA 3.37Å; S351-L354 WeakPolarHBondContact O-CB 3.43Å; S351-L354 PolarHBondContact O-N 3.16Å; M352-L354 PolarHBondContact O-N 3.42Å; L354-R356 PolarHBondContact O-N 3.24Å; L354-M374 HydrophobicContact CD2-CE 4.4Å; L354-M374 HydrophobicContact CD2-SD 4.25Å; L354-A519 HydrophobicContact CD1-CB 3.92Å; L354-K522 HydrophobicContact CD1-CD 4.32Å
355K70Confident64.3Low93 Ų9356 Ų5640%0.40433%0.328SS..  trans-64.6134.3171.4-173.3174.5-174.6175.50109.7S351 M352S351-K355 PolarHBondContact O-N 3.17Å; M352-K355 HydrophobicContact CE-CB 3.71Å; M352-K355 HydrophobicContact CE-CD 3.35Å; M352-K355 HydrophobicContact CE-CG 4.16Å; M352-K355 WeakPolarHBondContact O-CB 3.44Å; M352-K355 PolarHBondContact O-N 3.02Å
356R66.4Low62.8Low33 Ų3361.8 Ų61.813%0.12536%0.358CS..  trans-120155.6-180-59.6-66168.5-113.2-1.2110.8G353 L354 M374 E679G353-R356 PolarHBondContact O-NH1 3.22Å; G353-R356 PolarHBondContact O-NH2 3.29Å; L354-R356 PolarHBondContact O-N 3.24Å; R356-M374 PolarHBondContact NH2-SD 3.41Å; R356-M374 VanDerWaalsContact NH2-SD 3.36Å; R356-E679 WeakPolarHBondContact CD-OE1 3.22Å; R356-E679 VanDerWaalsContact CG-OE2 3.28Å; R356-E679 WeakPolarHBondContact CG-OE2 3.43Å; R356-E679 IonicContact NE-OE1 3.74Å; R356-E679 PolarHBondContact NE-OE1 2.99Å; R356-E679 VanDerWaalsContact NE-OE1 3.14Å; R356-E679 IonicContact NE-OE2 2.93Å; R356-E679 PolarHBondContact NE-OE2 3.19Å; R356-E679 VanDerWaalsContact NE-OE2 3.13Å
357K65.2Low61Low130 Ų13067.8 Ų67.857%0.56538%0.378SS*.PPolyproline II helixtrans-75.9160.5164.6-68.6-172.1179.3-174.20109F359 Q371K357-F359 PolarHBondContact O-N 3.39Å; K357-Q371 VanDerWaalsContact CD-OE1 3.29Å; K357-Q371 VanDerWaalsContact CE-OE1 3.29Å
358P60.8Low59.1Low80 Ų8075.6 Ų75.652%0.51941%0.407SS..PPolyproline II helixtrans-50.3142.5171.3-2634.7000111.7A360 Y682P358-A360 PolarHBondContact O-N 3.32Å; P358-Y682 VanDerWaalsContact CA-CE2 3.46Å; P358-Y682 HydrophobicContact CB-CE2 4.2Å
359F60Low57.5Low100 Ų10083.2 Ų83.244%0.43944%0.438SS..PPolyproline II helixtrans-53.9124177.5167.8-105.4000110.3K357 P361 Y682K357-F359 PolarHBondContact O-N 3.39Å; F359-P361 HydrophobicContact CE1-CB 3.67Å; F359-P361 HydrophobicContact CZ-CB 3.98Å; F359-Y682 HydrophobicContact CB-CD1 4.44Å; F359-Y682 HydrophobicContact CB-CE1 3.57Å; F359-Y682 WeakPolarHBondContact CB-OH 3.44Å; F359-Y682 VanDerWaalsContact N-CZ 3.32Å; F359-Y682 PolarHBondContact N-OH 3.11Å
360A54.3Low55.9Low31 Ų3183.6 Ų83.626%0.25644%0.435SS..PPolyproline II helixtrans-99.312016900000107.7P358P358-A360 PolarHBondContact O-N 3.32Å
361P54Low55.1Low16 Ų1686.5 Ų86.510%0.10444%0.437CS..PPolyproline II helixtrans-72155.5179.333.2-38000110.9F359 T363 A364 S733F359-P361 HydrophobicContact CE1-CB 3.67Å; F359-P361 HydrophobicContact CZ-CB 3.98Å; P361-T363 VanDerWaalsContact C-N 3.29Å; P361-T363 PolarHBondContact O-N 3.15Å; P361-A364 HydrophobicContact CG-CB 4.16Å; P361-A364 VanDerWaalsContact O-CB 3.23Å; P361-A364 WeakPolarHBondContact O-CB 3.28Å; P361-A364 PolarHBondContact O-N 3.41Å; P361-S733 VanDerWaalsContact CG-CB 3.49Å
362S50.8Low54.2Low33 Ų3393.8 Ų93.823%0.23147%0.468CS..THydrogen-bonded Turntrans-53.5-35.6-161.761.60000115.8S380S362-S380 WeakPolarHBondContact O-CB 3.48Å; S362-S380 PolarHBondContact O-OG 3.37Å
363T51.5Low53.2Low33 Ų3391.8 Ų91.820%0.20246%0.459CS..THydrogen-bonded Turntrans-88.4-3.9179.772.20000114.6P361 D365 S733P361-T363 VanDerWaalsContact C-N 3.29Å; P361-T363 PolarHBondContact O-N 3.15Å; T363-D365 VanDerWaalsContact C-N 3.27Å; T363-D365 PolarHBondContact O-N 3.28Å; T363-S733 CarbonylContact C-O 3.56Å; T363-S733 VanDerWaalsContact C-O 3.26Å; T363-S733 VanDerWaalsContact OG1-CA 3.32Å; T363-S733 WeakPolarHBondContact OG1-CA 3.5Å; T363-S733 WeakPolarHBondContact OG1-CB 3.33Å; T363-S733 PolarHBondContact OG1-O 3.34Å; T363-S733 PolarHBondContact OG1-OG 2.89Å
364A54.4Low52.5Low45 Ų4590.2 Ų90.237%0.37244%0.439SS..THydrogen-bonded Turntrans-66.7-30.6173.700000112.1P361 L366P361-A364 HydrophobicContact CG-CB 4.16Å; P361-A364 VanDerWaalsContact O-CB 3.23Å; P361-A364 WeakPolarHBondContact O-CB 3.28Å; P361-A364 PolarHBondContact O-N 3.41Å; A364-L366 PolarHBondContact O-N 3.17Å
365D49Very low52.2Low83 Ų8392 Ų9244%0.44445%0.451SS..THydrogen-bonded Turntrans-94.119.7-173.9-82.3-22.6000114.5T363 K367 Y368T363-D365 VanDerWaalsContact C-N 3.27Å; T363-D365 PolarHBondContact O-N 3.28Å; D365-K367 PolarHBondContact O-N 3.38Å; D365-Y368 PolarHBondContact O-N 2.68Å
366L48.2Very low51.9Low123 Ų12389 Ų8964%0.64444%0.44SS*.THydrogen-bonded Turntrans-60.26.5174.6-95.1163.8000114.5A364 L737A364-L366 PolarHBondContact O-N 3.17Å; L366-L737 HydrophobicContact CD1-CD1 4.38Å
367K41.7Very low51.9Low192 Ų19290.1 Ų90.184%0.83545%0.451SS*.THydrogen-bonded Turntrans-133.20.7169.8-90.6-174.3176.6177.30118.2D365D365-K367 PolarHBondContact O-N 3.38Å
368Y37.5Very low51.9Low199 Ų19989.5 Ų89.578%0.7845%0.446SS*.  trans-142.9137.7-179.7-93.3-85.9000115.2D365D365-Y368 PolarHBondContact O-N 2.68Å
369F36.3Very low52.1Low187 Ų18789.1 Ų89.182%0.8245%0.445SS*.  trans-79.1137.6-177.5-113.4-106.1000112.4
370L36.8Very low52Low149 Ų14986 Ų8678%0.7844%0.435SS*.  trans41.495.3149.7-58.4176.9000117.9
371Q43.9Very low52.4Low131 Ų13186.8 Ų86.861%0.61244%0.439SS*.  trans-119.5153.7163.6-150.115553.300111.8K357 I373K357-Q371 VanDerWaalsContact CD-OE1 3.29Å; K357-Q371 VanDerWaalsContact CE-OE1 3.29Å; Q371-I373 VanDerWaalsContact C-N 3.31Å; Q371-I373 PolarHBondContact O-N 2.89Å
372K48.7Very low52.7Low153 Ų15387.6 Ų87.667%0.66545%0.445SS*.  trans-68.967.2-165.5-161.6-179.1-174.6-179.20114
373I50.3Low52.9Low55 Ų5590.1 Ų90.128%0.28246%0.462SS..  trans-95.4136170.3-52.9173.7000108Q371 T375 R398Q371-I373 VanDerWaalsContact C-N 3.31Å; Q371-I373 PolarHBondContact O-N 2.89Å; I373-T375 VanDerWaalsContact CG2-O 3.28Å; I373-T375 WeakPolarHBondContact CG2-O 3.38Å; I373-R398 PolarHBondContact O-NH1 3.49Å; I373-R398 PolarHBondContact O-NH2 3.46Å
374M54.1Low53.1Low13 Ų1392.9 Ų92.96%0.06448%0.479CS..SBendtrans-60.2-57.6173.1-54.7-138.1-6900109L354 R356 V376 R398 D675 E679L354-M374 HydrophobicContact CD2-CE 4.4Å; L354-M374 HydrophobicContact CD2-SD 4.25Å; R356-M374 PolarHBondContact NH2-SD 3.41Å; R356-M374 VanDerWaalsContact NH2-SD 3.36Å; M374-V376 PolarHBondContact O-N 3.18Å; M374-V376 VanDerWaalsContact O-N 3.12Å; M374-R398 VanDerWaalsContact CA-NH2 3.3Å; M374-D675 CarbonylContact C-O 3.59Å; M374-D675 CarbonylContact O-C 3.55Å; M374-E679 WeakPolarHBondContact CA-OE1 3.15Å; M374-E679 WeakPolarHBondContact CB-OE1 3.32Å; M374-E679 WeakPolarHBondContact CG-OE1 3.5Å; M374-E679 PolarHBondContact N-OE1 2.89Å
375T62.9Low53.4Low52 Ų5295.7 Ų95.732%0.31950%0.503SS..SBendtrans-61.4115.2178.6-440000110.6I373 T377 D675 D677 E679I373-T375 VanDerWaalsContact CG2-O 3.28Å; I373-T375 WeakPolarHBondContact CG2-O 3.38Å; T375-T377 PolarHBondContact O-N 3.14Å; T375-D675 WeakPolarHBondContact CA-O 3.35Å; T375-D675 PolarHBondContact N-O 3.36Å; T375-D677 PolarHBondContact OG1-O 3.03Å; T375-E679 PolarHBondContact N-OE1 2.79Å; T375-E679 WeakPolarHBondContact OG1-CG 3.46Å
376V63.8Low54.4Low31 Ų3195.1 Ų95.119%0.18850%0.502CS..  trans-79.599.9177.3-179.30000108.7M374 Y378 L396 R398M374-V376 PolarHBondContact O-N 3.18Å; M374-V376 VanDerWaalsContact O-N 3.12Å; V376-Y378 VanDerWaalsContact O-CD1 3.31Å; V376-Y378 WeakPolarHBondContact O-CD1 3.43Å; V376-Y378 PolarHBondContact O-N 3.27Å; V376-L396 HydrophobicContact CG1-CD1 4.24Å; V376-R398 HydrophobicContact CG2-CB 4Å; V376-R398 HydrophobicContact CG2-CG 3.74Å
377T64.8Low55.3Low56 Ų5698 Ų9834%0.34452%0.517SS..  trans-78.3105.9177.456.10000110.6T375T375-T377 PolarHBondContact O-N 3.14Å
378Y66.4Low56.7Low118 Ų11891.3 Ų91.346%0.46350%0.495SS..  trans-108.9-2178.159.2-96.7000114V376 S380 S381 C382 L393V376-Y378 VanDerWaalsContact O-CD1 3.31Å; V376-Y378 WeakPolarHBondContact O-CD1 3.43Å; V376-Y378 PolarHBondContact O-N 3.27Å; Y378-S380 PolarHBondContact O-N 3.37Å; Y378-S380 VanDerWaalsContact O-N 3.1Å; Y378-S381 WeakPolarHBondContact O-CA 3.09Å; Y378-S381 VanDerWaalsContact O-CB 3.32Å; Y378-S381 WeakPolarHBondContact O-CB 3.44Å; Y378-S381 PolarHBondContact O-N 2.78Å; Y378-C382 PolarHBondContact O-N 2.88Å; Y378-C382 VanDerWaalsContact O-N 3.13Å; Y378-L393 HydrophobicContact CD2-CD1 3.64Å; Y378-L393 HydrophobicContact CD2-CD2 4.48Å; Y378-L393 HydrophobicContact CE2-CD1 4.16Å; Y378-L393 HydrophobicContact CG-CD1 3.97Å; Y378-L393 HydrophobicContact CG-CD2 4.24Å
379S64.3Low58.1Low71 Ų7182.1 Ų82.150%0.49746%0.46SS..THydrogen-bonded Turntrans-57.1-32.5-173.1-43.80000113.7C382 S383S379-C382 CarbonylContact O-C 3.56Å; S379-C382 PolarHBondContact O-N 3.14Å; S379-S383 PolarHBondContact O-N 3.15Å
380S59.4Low59.8Low34 Ų3480.6 Ų80.624%0.23845%0.453CS..THydrogen-bonded Turntrans-76.8-27174.8480000113.5S362 Y378 C382 S383S362-S380 WeakPolarHBondContact O-CB 3.48Å; S362-S380 PolarHBondContact O-OG 3.37Å; Y378-S380 PolarHBondContact O-N 3.37Å; Y378-S380 VanDerWaalsContact O-N 3.1Å; S380-C382 PolarHBondContact O-N 2.71Å; S380-S383 PolarHBondContact O-N 3.42Å; S380-S383 PolarHBondContact O-OG 3.14Å; S380-S383 VanDerWaalsContact O-OG 3.05Å
381S61.4Low61.7Low49 Ų4976 Ų7634%0.34343%0.433SS..THydrogen-bonded Turntrans-70.7-24.5171.8-63.40000111.4Y378 R392Y378-S381 WeakPolarHBondContact O-CA 3.09Å; Y378-S381 VanDerWaalsContact O-CB 3.32Å; Y378-S381 WeakPolarHBondContact O-CB 3.44Å; Y378-S381 PolarHBondContact O-N 2.78Å; S381-R392 PolarHBondContact O-NH2 2.97Å
382C59.6Low63Low33 Ų3375.4 Ų75.422%0.22343%0.425CS..THydrogen-bonded Turntrans-104.66.5176.7-640000114.4Y378 S379 S380 T384 L393Y378-C382 PolarHBondContact O-N 2.88Å; Y378-C382 VanDerWaalsContact O-N 3.13Å; S379-C382 CarbonylContact O-C 3.56Å; S379-C382 PolarHBondContact O-N 3.14Å; S380-C382 PolarHBondContact O-N 2.71Å; C382-T384 PolarHBondContact O-N 3.48Å; C382-L393 VanDerWaalsContact SG-CD1 3.55Å
383S56.6Low64.4Low85 Ų8569.7 Ų69.759%0.59440%0.402SS*.SBendtrans-64.4-25.2-176.261.80000112.7S379 S380S379-S383 PolarHBondContact O-N 3.15Å; S380-S383 PolarHBondContact O-N 3.42Å; S380-S383 PolarHBondContact O-OG 3.14Å; S380-S383 VanDerWaalsContact O-OG 3.05Å
384T55.4Low65.9Low91 Ų9172 Ų7256%0.55841%0.414SS*.SBendtrans-116.1122174.7-39.10000108.3C382 T386 S389C382-T384 PolarHBondContact O-N 3.48Å; T384-T386 HydrophobicContact CG2-CG2 4.23Å; T384-T386 PolarHBondContact O-N 2.66Å; T384-T386 VanDerWaalsContact O-N 3.11Å; T384-S389 PolarHBondContact O-OG 2.78Å
385A60.6Low67.3Low105 Ų10578.6 Ų78.687%0.86845%0.449SS*.  trans-71104.4173.200000109.1
386T70Confident68.1Low71 Ų7179.1 Ų79.144%0.43645%0.45SS..  trans-123.8159.1171.169.90000108T384 S388 S389T384-T386 HydrophobicContact CG2-CG2 4.23Å; T384-T386 PolarHBondContact O-N 2.66Å; T384-T386 VanDerWaalsContact O-N 3.11Å; T386-S388 PolarHBondContact O-N 3.48Å; T386-S389 PolarHBondContact N-OG 2.84Å; T386-S389 VanDerWaalsContact N-OG 3.08Å; T386-S389 PolarHBondContact O-N 3.01Å; T386-S389 PolarHBondContact O-OG 3.46Å; T386-S389 PolarHBondContact OG1-N 3.42Å; T386-S389 PolarHBondContact OG1-OG 3.36Å
387L67.2Low69.1Low182 Ų18284.6 Ų84.695%0.95347%0.467SS*.THydrogen-bonded Turntrans-50.6-33.4177-175.169.1000112.2
388S70.9Confident69.7Low53 Ų5385.6 Ų85.637%0.37147%0.465SS..THydrogen-bonded Turntrans-95.90.4-177.2-170.70000114.9T386 S391 R392T386-S388 PolarHBondContact O-N 3.48Å; S388-S391 WeakPolarHBondContact CA-OG 3.49Å; S388-S391 PolarHBondContact O-N 2.9Å; S388-S391 PolarHBondContact O-OG 3.12Å; S388-S391 PolarHBondContact OG-OG 2.57Å; S388-R392 WeakPolarHBondContact O-CG 3.44Å; S388-R392 PolarHBondContact O-N 3.4Å; S388-R392 PolarHBondContact O-NE 3.41Å
389S66.4Low70.3Confident5 Ų581.3 Ų81.34%0.03546%0.456CS..Hα-helixtrans-63.3-48.3-173.7-650000112.4T384 T386T384-S389 PolarHBondContact O-OG 2.78Å; T386-S389 PolarHBondContact N-OG 2.84Å; T386-S389 VanDerWaalsContact N-OG 3.08Å; T386-S389 PolarHBondContact O-N 3.01Å; T386-S389 PolarHBondContact O-OG 3.46Å; T386-S389 PolarHBondContact OG1-N 3.42Å; T386-S389 PolarHBondContact OG1-OG 3.36Å
390F72.1Confident71.4Confident155 Ų15578.5 Ų78.568%0.6844%0.437SS*.Hα-helixtrans-77-30.3174.8-69.7-45.3000113.4R392 L393 L394F390-R392 VanDerWaalsContact C-N 3.25Å; F390-R392 PolarHBondContact O-N 2.78Å; F390-L393 HydrophobicContact CD1-CD1 4.02Å; F390-L393 WeakPolarHBondContact O-CB 3.36Å; F390-L393 PolarHBondContact O-N 2.94Å; F390-L394 PolarHBondContact O-N 3.02Å
391S76.4Confident72.7Confident53 Ų5378.7 Ų78.737%0.37144%0.437SS..Hα-helixtrans-63.6-33177.670.60000112.3S388 L393 L394S388-S391 WeakPolarHBondContact CA-OG 3.49Å; S388-S391 PolarHBondContact O-N 2.9Å; S388-S391 PolarHBondContact O-OG 3.12Å; S388-S391 PolarHBondContact OG-OG 2.57Å; S391-L393 VanDerWaalsContact C-N 3.3Å; S391-L393 PolarHBondContact O-N 2.77Å; S391-L394 WeakPolarHBondContact O-CB 3.26Å; S391-L394 PolarHBondContact O-N 2.85Å
392R71.6Confident74.1Confident118 Ų11880.3 Ų80.345%0.44544%0.436SS..Hα-helixtrans-64-33.5171.8-74.3-177.9-68.6161.90.2112.8S381 S388 F390 L394 L395S381-R392 PolarHBondContact O-NH2 2.97Å; S388-R392 WeakPolarHBondContact O-CG 3.44Å; S388-R392 PolarHBondContact O-N 3.4Å; S388-R392 PolarHBondContact O-NE 3.41Å; F390-R392 VanDerWaalsContact C-N 3.25Å; F390-R392 PolarHBondContact O-N 2.78Å; R392-L394 VanDerWaalsContact C-N 3.32Å; R392-L395 PolarHBondContact O-N 2.83Å
393L78.5Confident75.5Confident34 Ų3482.1 Ų82.118%0.17844%0.44CS..Hα-helixtrans-68.5-33.3176.4-57.6-164.4000112.1Y378 C382 F390 S391 L395 L396Y378-L393 HydrophobicContact CD2-CD1 3.64Å; Y378-L393 HydrophobicContact CD2-CD2 4.48Å; Y378-L393 HydrophobicContact CE2-CD1 4.16Å; Y378-L393 HydrophobicContact CG-CD1 3.97Å; Y378-L393 HydrophobicContact CG-CD2 4.24Å; C382-L393 VanDerWaalsContact SG-CD1 3.55Å; F390-L393 HydrophobicContact CD1-CD1 4.02Å; F390-L393 WeakPolarHBondContact O-CB 3.36Å; F390-L393 PolarHBondContact O-N 2.94Å; S391-L393 VanDerWaalsContact C-N 3.3Å; S391-L393 PolarHBondContact O-N 2.77Å; L393-L395 PolarHBondContact O-N 3.04Å; L393-L396 HydrophobicContact CD2-CD1 3.94Å; L393-L396 WeakPolarHBondContact O-CB 3.07Å; L393-L396 PolarHBondContact O-N 2.96Å; L393-L396 VanDerWaalsContact O-N 3.09Å
394L81.9Confident77Confident102 Ų10279.5 Ų79.553%0.53442%0.419SS..Hα-helixtrans-62.3-21.2174.9-62176.1000112.4F390 S391 R392 Y402F390-L394 PolarHBondContact O-N 3.02Å; S391-L394 WeakPolarHBondContact O-CB 3.26Å; S391-L394 PolarHBondContact O-N 2.85Å; R392-L394 VanDerWaalsContact C-N 3.32Å; L394-Y402 WeakPolarHBondContact O-CE2 3.27Å
395L82.5Confident78.7Confident152 Ų15275.3 Ų75.380%0.79639%0.393SS*.THydrogen-bonded Turntrans-90.2-5.3178.1-61.4176.9000113.3R392 L393R392-L395 PolarHBondContact O-N 2.83Å; L393-L395 PolarHBondContact O-N 3.04Å
396L80Confident80.3Confident64 Ų6474.7 Ų74.734%0.33537%0.371SS..  trans-72.6130.9174.6-64.8175000109.3V376 L393 S400V376-L396 HydrophobicContact CG1-CD1 4.24Å; L393-L396 HydrophobicContact CD2-CD1 3.94Å; L393-L396 WeakPolarHBondContact O-CB 3.07Å; L393-L396 PolarHBondContact O-N 2.96Å; L393-L396 VanDerWaalsContact O-N 3.09Å; L396-S400 WeakPolarHBondContact O-CB 3.33Å; L396-S400 PolarHBondContact O-OG 3.42Å
397W84.7Confident81.3Confident146 Ų14676.5 Ų76.555%0.55337%0.373SS*.  trans-84.4-40174.3-178.6-109.5000112.1S400 K403 F406W397-S400 PolarHBondContact O-OG 3.29Å; W397-K403 HydrophobicContact CD2-CB 4.15Å; W397-K403 HydrophobicContact CH2-CB 4.42Å; W397-K403 HydrophobicContact CZ2-CB 4.03Å; W397-K403 HydrophobicContact CZ2-CG 4.22Å; W397-K403 WeakPolarHBondContact O-CB 3.38Å; W397-F406 HydrophobicContact CH2-CB 4.2Å; W397-F406 HydrophobicContact CH2-CD1 4.08Å; W397-F406 HydrophobicContact CH2-CG 4.15Å; W397-F406 HydrophobicContact CZ2-CD1 4.16Å; W397-F406 HydrophobicContact CZ2-CE1 4.39Å
398R78.7Confident82.5Confident76 Ų7668.3 Ų68.329%0.28733%0.33SS..THydrogen-bonded Turntrans-77.4139.8179.8-163.5177.9-169.5-179.3-2.8110.2I373 M374 V376 S400 D675I373-R398 PolarHBondContact O-NH1 3.49Å; I373-R398 PolarHBondContact O-NH2 3.46Å; M374-R398 VanDerWaalsContact CA-NH2 3.3Å; V376-R398 HydrophobicContact CG2-CB 4Å; V376-R398 HydrophobicContact CG2-CG 3.74Å; R398-S400 PolarHBondContact O-N 3.29Å; R398-D675 HydrophobicContact CG-CB 4.38Å; R398-D675 VanDerWaalsContact CG-CG 3.43Å; R398-D675 WeakPolarHBondContact CG-OD1 3.49Å; R398-D675 WeakPolarHBondContact CG-OD2 3.48Å; R398-D675 IonicContact CZ-OD1 3.57Å; R398-D675 IonicContact NE-OD1 3.69Å; R398-D675 PolarHBondContact NE-OD1 3.35Å; R398-D675 IonicContact NH2-OD1 3.59Å
399G77.4Confident83.7Confident28 Ų2867.2 Ų67.229%0.28932%0.32SS..THydrogen-bonded Turntrans62.916.2-177.300000114D675G399-D675 PolarHBondContact N-OD2 2.85Å
400S87.8Confident85Confident12 Ų1274 Ų748%0.08435%0.349CS..SBendtrans-103.1154.1-176.378.20000113L396 W397 R398 Y402 K403 I404L396-S400 WeakPolarHBondContact O-CB 3.33Å; L396-S400 PolarHBondContact O-OG 3.42Å; W397-S400 PolarHBondContact O-OG 3.29Å; R398-S400 PolarHBondContact O-N 3.29Å; S400-Y402 PolarHBondContact O-N 2.92Å; S400-K403 PolarHBondContact O-N 2.91Å; S400-K403 VanDerWaalsContact O-N 3.13Å; S400-I404 PolarHBondContact O-N 2.91Å
401V87.7Confident86.1Confident39 Ų3970 Ų7024%0.23633%0.334CS..Hα-helixtrans-55.1-36.4176.171.90000111.3K403 I404 I405 I655 G659V401-K403 PolarHBondContact O-N 2.8Å; V401-I404 WeakPolarHBondContact O-CG1 3.48Å; V401-I404 PolarHBondContact O-N 3.34Å; V401-I405 HydrophobicContact CG2-CD1 4.37Å; V401-I405 HydrophobicContact CG2-CG2 4.18Å; V401-I405 VanDerWaalsContact O-CG1 3.25Å; V401-I405 WeakPolarHBondContact O-CG1 3.45Å; V401-I405 WeakPolarHBondContact O-CG2 3.49Å; V401-I405 PolarHBondContact O-N 3.32Å; V401-I405 VanDerWaalsContact O-N 3.08Å; V401-I655 HydrophobicContact CG1-CG2 4.29Å; V401-G659 VanDerWaalsContact CG2-CA 3.42Å
402Y89.2Confident86.9Confident82 Ų8268 Ų6832%0.32232%0.318SS..Hα-helixtrans-62.3-43.9179.8-51.1-69.7000112.1L394 S400 I404 I405 F406L394-Y402 WeakPolarHBondContact O-CE2 3.27Å; S400-Y402 PolarHBondContact O-N 2.92Å; Y402-I404 VanDerWaalsContact C-N 3.31Å; Y402-I404 PolarHBondContact O-N 3.14Å; Y402-I405 PolarHBondContact O-N 3.12Å; Y402-F406 WeakPolarHBondContact O-CB 3.27Å; Y402-F406 PolarHBondContact O-N 3.38Å
403K89.2Confident88Confident71 Ų7164.1 Ų64.131%0.30931%0.306SS..Hα-helixtrans-65.5-32.6179.6176.5-173.1169.4-165.80112.8W397 S400 V401 F406 D675W397-K403 HydrophobicContact CD2-CB 4.15Å; W397-K403 HydrophobicContact CH2-CB 4.42Å; W397-K403 HydrophobicContact CZ2-CB 4.03Å; W397-K403 HydrophobicContact CZ2-CG 4.22Å; W397-K403 WeakPolarHBondContact O-CB 3.38Å; S400-K403 PolarHBondContact O-N 2.91Å; S400-K403 VanDerWaalsContact O-N 3.13Å; V401-K403 PolarHBondContact O-N 2.8Å; K403-F406 WeakPolarHBondContact O-CD1 3.37Å; K403-F406 VanDerWaalsContact O-CE1 3.31Å; K403-F406 WeakPolarHBondContact O-CE1 3.25Å; K403-D675 VanDerWaalsContact NZ-CG 3.29Å; K403-D675 IonicContact NZ-OD1 3.1Å; K403-D675 PolarHBondContact NZ-OD1 3.48Å; K403-D675 IonicContact NZ-OD2 2.71Å; K403-D675 PolarHBondContact NZ-OD2 3.48Å
404I88.4Confident88.8Confident31 Ų3164.6 Ų64.616%0.15932%0.315CS..Hα-helixtrans-85.6-22.8-17962.7-177.7000112.9V12 S400 V401 Y402 K662V12-I404 HydrophobicContact CG1-CB 4.18Å; V12-I404 HydrophobicContact CG1-CG2 4.41Å; S400-I404 PolarHBondContact O-N 2.91Å; V401-I404 WeakPolarHBondContact O-CG1 3.48Å; V401-I404 PolarHBondContact O-N 3.34Å; Y402-I404 VanDerWaalsContact C-N 3.31Å; Y402-I404 PolarHBondContact O-N 3.14Å; I404-K662 HydrophobicContact CB-CB 4.41Å; I404-K662 HydrophobicContact CD1-CB 3.58Å; I404-K662 HydrophobicContact CG1-CB 3.94Å
405I92.1Very high89.3Confident2 Ų263.3 Ų63.31%0.0131%0.308CS..Hα-helixtrans-102.4-16.5-179.774.9-175.9000114.7V401 Y402 K407 D408 L409 I655 I658 K662V401-I405 HydrophobicContact CG2-CD1 4.37Å; V401-I405 HydrophobicContact CG2-CG2 4.18Å; V401-I405 VanDerWaalsContact O-CG1 3.25Å; V401-I405 WeakPolarHBondContact O-CG1 3.45Å; V401-I405 WeakPolarHBondContact O-CG2 3.49Å; V401-I405 PolarHBondContact O-N 3.32Å; V401-I405 VanDerWaalsContact O-N 3.08Å; Y402-I405 PolarHBondContact O-N 3.12Å; I405-K407 PolarHBondContact O-N 3.36Å; I405-D408 PolarHBondContact O-N 3.4Å; I405-L409 WeakPolarHBondContact O-CB 3.42Å; I405-L409 PolarHBondContact O-N 3.17Å; I405-I655 HydrophobicContact CD1-CB 4.08Å; I405-I655 HydrophobicContact CD1-CG1 3.69Å; I405-I655 HydrophobicContact CD1-CG2 4.18Å; I405-I658 HydrophobicContact CB-CG2 4.34Å; I405-I658 HydrophobicContact CG2-CG2 3.91Å; I405-K662 HydrophobicContact CG2-CG 4.13Å
406F92.9Very high89.7Confident92 Ų9256.3 Ų56.340%0.40427%0.271SS..Hα-helixtrans-57.2-34-166.778.7-80.6000113.7W397 Y402 K403 F410W397-F406 HydrophobicContact CH2-CB 4.2Å; W397-F406 HydrophobicContact CH2-CD1 4.08Å; W397-F406 HydrophobicContact CH2-CG 4.15Å; W397-F406 HydrophobicContact CZ2-CD1 4.16Å; W397-F406 HydrophobicContact CZ2-CE1 4.39Å; Y402-F406 WeakPolarHBondContact O-CB 3.27Å; Y402-F406 PolarHBondContact O-N 3.38Å; K403-F406 WeakPolarHBondContact O-CD1 3.37Å; K403-F406 VanDerWaalsContact O-CE1 3.31Å; K403-F406 WeakPolarHBondContact O-CE1 3.25Å; F406-F410 WeakPolarHBondContact O-CB 3.2Å; F406-F410 PolarHBondContact O-N 3.19Å
407K92.6Very high90.2Very high109 Ų10957.2 Ų57.247%0.47427%0.271SS..Hα-helixtrans-69.2-46.7176.7-64.1-175.2-179.6179.30111.3L14 I405 L409 F410 I411L14-K407 HydrophobicContact CB-CD 4.44Å; L14-K407 HydrophobicContact CD1-CB 4.14Å; I405-K407 PolarHBondContact O-N 3.36Å; K407-L409 VanDerWaalsContact C-N 3.32Å; K407-F410 PolarHBondContact O-N 3.1Å; K407-I411 WeakPolarHBondContact O-CG1 3.45Å; K407-I411 PolarHBondContact O-N 3.13Å
408D92.6Very high90.6Very high11 Ų1154.3 Ų54.36%0.05927%0.269CS..Hα-helixtrans-61.5-43.4176.5-57.6-106.3000110.3L14 I405 I411 F412 Y622 F654 I658 K662L14-D408 HydrophobicContact CD1-CB 4.36Å; I405-D408 PolarHBondContact O-N 3.4Å; D408-I411 PolarHBondContact O-N 3.4Å; D408-F412 WeakPolarHBondContact O-CB 3.25Å; D408-F412 PolarHBondContact O-N 3.32Å; D408-Y622 PolarHBondContact OD1-OH 3.34Å; D408-F654 VanDerWaalsContact C-CZ 3.48Å; D408-F654 HydrophobicContact CB-CE1 4.03Å; D408-F654 HydrophobicContact CB-CZ 3.84Å; D408-F654 WeakPolarHBondContact O-CZ 3.19Å; D408-I658 HydrophobicContact CB-CG2 4.35Å; D408-K662 VanDerWaalsContact CG-NZ 3.3Å; D408-K662 WeakPolarHBondContact OD1-CE 3.13Å; D408-K662 IonicContact OD1-NZ 2.72Å; D408-K662 PolarHBondContact OD1-NZ 3.11Å; D408-K662 VanDerWaalsContact OD2-CE 3.25Å; D408-K662 WeakPolarHBondContact OD2-CE 2.99Å; D408-K662 IonicContact OD2-NZ 2.78Å; D408-K662 PolarHBondContact OD2-NZ 3.26Å
409L94.5Very high91.1Very high30 Ų3053 Ų5316%0.15727%0.268CS..Hα-helixtrans-65.1-42.6177.2-179.762.6000111.8I405 K407 I411 F412 L413 I651 F654I405-L409 WeakPolarHBondContact O-CB 3.42Å; I405-L409 PolarHBondContact O-N 3.17Å; K407-L409 VanDerWaalsContact C-N 3.32Å; L409-I411 PolarHBondContact O-N 3.11Å; L409-F412 PolarHBondContact O-N 3.23Å; L409-L413 HydrophobicContact CD1-CD1 4.21Å; L409-L413 HydrophobicContact CD1-CG 4.16Å; L409-L413 HydrophobicContact CG-CD1 4.08Å; L409-L413 HydrophobicContact CG-CG 4.43Å; L409-L413 WeakPolarHBondContact O-CB 3.18Å; L409-L413 VanDerWaalsContact O-CG 3.31Å; L409-L413 WeakPolarHBondContact O-CG 3.41Å; L409-L413 PolarHBondContact O-N 3.31Å; L409-I651 HydrophobicContact CD1-CG1 4.49Å; L409-I651 HydrophobicContact CD1-CG2 4.34Å; L409-I651 HydrophobicContact CD2-CG2 4.44Å; L409-F654 HydrophobicContact CB-CD1 4.05Å; L409-F654 HydrophobicContact CB-CE1 3.79Å; L409-F654 HydrophobicContact CD1-CB 4.3Å; L409-F654 HydrophobicContact CD1-CD1 3.75Å; L409-F654 HydrophobicContact CD1-CE1 4.22Å; L409-F654 HydrophobicContact CD1-CG 3.98Å; L409-F654 HydrophobicContact CG-CD1 4.47Å
410F95.2Very high91.5Very high147 Ų14753 Ų5365%0.64526%0.261SS*.Hα-helixtrans-60.6-45.1176.4176.9-96.6000111.4F406 K407 L413 A414F406-F410 WeakPolarHBondContact O-CB 3.2Å; F406-F410 PolarHBondContact O-N 3.19Å; K407-F410 PolarHBondContact O-N 3.1Å; F410-L413 PolarHBondContact O-N 3.11Å; F410-A414 VanDerWaalsContact O-CB 3.3Å; F410-A414 WeakPolarHBondContact O-CB 3.21Å; F410-A414 PolarHBondContact O-N 2.93Å
411I94.2Very high91.5Very high70 Ų7056.8 Ų56.836%0.35928%0.28SS..Hα-helixtrans-64.3-44.6177.1-70.6164.4000110.7L14 K407 D408 L409 L413 A414 I415L14-I411 HydrophobicContact CD1-CD1 3.64Å; L14-I411 HydrophobicContact CD2-CD1 3.37Å; L14-I411 HydrophobicContact CG-CD1 4.11Å; K407-I411 WeakPolarHBondContact O-CG1 3.45Å; K407-I411 PolarHBondContact O-N 3.13Å; D408-I411 PolarHBondContact O-N 3.4Å; L409-I411 PolarHBondContact O-N 3.11Å; I411-L413 PolarHBondContact O-N 3.35Å; I411-A414 PolarHBondContact O-N 3.44Å; I411-I415 HydrophobicContact CG2-CD1 3.86Å; I411-I415 WeakPolarHBondContact O-CG1 3.25Å; I411-I415 PolarHBondContact O-N 3.49Å
412F94.1Very high91.5Very high11 Ų1157.3 Ų57.35%0.04828%0.283CS..Hα-helixtrans-57.5-48.4176.1177.9-92.8000111.5D408 L409 I415 Y416 F625 C628 L629 V650 F654D408-F412 WeakPolarHBondContact O-CB 3.25Å; D408-F412 PolarHBondContact O-N 3.32Å; L409-F412 PolarHBondContact O-N 3.23Å; F412-I415 PolarHBondContact O-N 3.28Å; F412-Y416 VanDerWaalsContact O-CB 3.29Å; F412-Y416 WeakPolarHBondContact O-CB 3.22Å; F412-Y416 PolarHBondContact O-N 3.38Å; F412-F625 HydrophobicContact CD2-CB 4.23Å; F412-F625 HydrophobicContact CE2-CB 3.92Å; F412-F625 AromaticContact CE2-CD1 3.98Å; F412-F625 HydrophobicContact CE2-CD1 3.98Å; F412-F625 HydrophobicContact CE2-CG 4.37Å; F412-F625 HydrophobicContact CZ-CD1 4.28Å; F412-C628 HydrophobicContact CZ-CB 4.43Å; F412-L629 HydrophobicContact CD2-CD1 4.49Å; F412-L629 HydrophobicContact CD2-CD2 3.79Å; F412-L629 HydrophobicContact CD2-CG 4.05Å; F412-L629 HydrophobicContact CE1-CD2 4.5Å; F412-L629 HydrophobicContact CE2-CD1 4.46Å; F412-L629 HydrophobicContact CE2-CD2 3.53Å; F412-L629 HydrophobicContact CE2-CG 3.62Å; F412-L629 HydrophobicContact CG-CD2 4.39Å; F412-L629 HydrophobicContact CZ-CD2 3.9Å; F412-L629 HydrophobicContact CZ-CG 4.31Å; F412-V650 HydrophobicContact CE1-CG1 3.7Å; F412-V650 HydrophobicContact CZ-CG1 3.54Å; F412-F654 HydrophobicContact CB-CD2 4.13Å; F412-F654 HydrophobicContact CB-CE2 3.48Å; F412-F654 VanDerWaalsContact CB-CE2 3.48Å; F412-F654 HydrophobicContact CB-CZ 3.93Å; F412-F654 AromaticContact CD1-CD2 3.99Å; F412-F654 HydrophobicContact CD1-CD2 3.99Å; F412-F654 HydrophobicContact CD1-CE2 4.22Å; F412-F654 AromaticContact CD2-CD2 3.92Å; F412-F654 HydrophobicContact CD2-CD2 3.92Å; F412-F654 AromaticContact CD2-CE2 3.67Å; F412-F654 HydrophobicContact CD2-CE2 3.67Å; F412-F654 HydrophobicContact CE1-CD2 4.44Å; F412-F654 HydrophobicContact CE2-CD2 4.35Å; F412-F654 HydrophobicContact CE2-CE2 4.48Å; F412-F654 AromaticContact CG-CD2 3.73Å; F412-F654 HydrophobicContact CG-CD2 3.73Å; F412-F654 AromaticContact CG-CE2 3.51Å; F412-F654 HydrophobicContact CG-CE2 3.51Å; F412-F654 HydrophobicContact CG-CZ 4.41Å
413L93.7Very high91.4Very high38 Ų3853.9 Ų53.920%0.19927%0.269CS..Hα-helixtrans-65.3-39.4177.6-70.8176000112.2L409 F410 I411 I415 Y416 Y417 P647 I651L409-L413 HydrophobicContact CD1-CD1 4.21Å; L409-L413 HydrophobicContact CD1-CG 4.16Å; L409-L413 HydrophobicContact CG-CD1 4.08Å; L409-L413 HydrophobicContact CG-CG 4.43Å; L409-L413 WeakPolarHBondContact O-CB 3.18Å; L409-L413 VanDerWaalsContact O-CG 3.31Å; L409-L413 WeakPolarHBondContact O-CG 3.41Å; L409-L413 PolarHBondContact O-N 3.31Å; F410-L413 PolarHBondContact O-N 3.11Å; I411-L413 PolarHBondContact O-N 3.35Å; L413-I415 PolarHBondContact O-N 3.27Å; L413-Y416 PolarHBondContact O-N 3.07Å; L413-Y417 HydrophobicContact CB-CD2 4.3Å; L413-Y417 HydrophobicContact CB-CE2 4.3Å; L413-Y417 HydrophobicContact CD2-CE2 4.2Å; L413-Y417 WeakPolarHBondContact O-CB 3.42Å; L413-Y417 WeakPolarHBondContact O-CD2 3.35Å; L413-Y417 PolarHBondContact O-N 3.08Å; L413-P647 HydrophobicContact CD2-CG 4.16Å; L413-I651 HydrophobicContact CD2-CD1 4.06Å; L413-I651 HydrophobicContact CD2-CG1 4.01Å
414A94.6Very high91.1Very high44 Ų4454.1 Ų54.136%0.36427%0.272SS..Hα-helixtrans-60.3-45.417600000111.2F410 I411 T418F410-A414 VanDerWaalsContact O-CB 3.3Å; F410-A414 WeakPolarHBondContact O-CB 3.21Å; F410-A414 PolarHBondContact O-N 2.93Å; I411-A414 PolarHBondContact O-N 3.44Å; A414-T418 VanDerWaalsContact O-CB 3.28Å; A414-T418 WeakPolarHBondContact O-CB 3.29Å; A414-T418 PolarHBondContact O-N 3.24Å; A414-T418 PolarHBondContact O-OG1 3.07Å
415I94.1Very high91.1Very high75 Ų7559.8 Ų59.839%0.38530%0.297SS..Hα-helixtrans-66.6-44.9175.9-62166.5000110.4I411 F412 L413 Y417 T418 L419 L629I411-I415 HydrophobicContact CG2-CD1 3.86Å; I411-I415 WeakPolarHBondContact O-CG1 3.25Å; I411-I415 PolarHBondContact O-N 3.49Å; F412-I415 PolarHBondContact O-N 3.28Å; L413-I415 PolarHBondContact O-N 3.27Å; I415-Y417 PolarHBondContact O-N 3.18Å; I415-T418 PolarHBondContact O-N 2.98Å; I415-L419 HydrophobicContact CG2-CD1 4.12Å; I415-L419 HydrophobicContact CG2-CG 4.46Å; I415-L419 WeakPolarHBondContact O-CG 3.41Å; I415-L419 PolarHBondContact O-N 3.45Å; I415-L629 HydrophobicContact CB-CD1 4.35Å; I415-L629 HydrophobicContact CB-CD2 4.22Å; I415-L629 HydrophobicContact CG2-CD1 3.73Å; I415-L629 HydrophobicContact CG2-CD2 4.03Å; I415-L629 HydrophobicContact CG2-CG 4.45Å
416Y91Very high91.1Very high5 Ų564 Ų642%0.0233%0.325CS..Hα-helixtrans-56-51.5178.9-177.6-90.3000111.6F412 L413 L419 N420 L629 R632 Q633 P647F412-Y416 VanDerWaalsContact O-CB 3.29Å; F412-Y416 WeakPolarHBondContact O-CB 3.22Å; F412-Y416 PolarHBondContact O-N 3.38Å; L413-Y416 PolarHBondContact O-N 3.07Å; Y416-L419 PolarHBondContact O-N 3.35Å; Y416-N420 WeakPolarHBondContact O-CB 3.37Å; Y416-N420 PolarHBondContact O-N 3.31Å; Y416-L629 HydrophobicContact CD2-CD2 4.37Å; Y416-R632 PolarHBondContact OH-O 3.45Å; Y416-Q633 HydrophobicContact CE2-CG 4.49Å; Y416-Q633 PolarHBondContact O-NE2 2.86Å; Y416-Q633 VanDerWaalsContact O-NE2 3.09Å; Y416-P647 HydrophobicContact CD1-CG 3.93Å; Y416-P647 HydrophobicContact CE1-CB 3.96Å; Y416-P647 HydrophobicContact CE1-CG 3.65Å; Y416-P647 HydrophobicContact CE2-CB 4.2Å; Y416-P647 HydrophobicContact CE2-CG 4.37Å; Y416-P647 HydrophobicContact CG-CG 4.41Å
417Y90.5Very high90.8Very high83 Ų8362.5 Ų62.533%0.32532%0.319SS..Hα-helixtrans-71.3-31.7179.1-73-61.3000112.7L413 I415 L419 N420 L421L413-Y417 HydrophobicContact CB-CD2 4.3Å; L413-Y417 HydrophobicContact CB-CE2 4.3Å; L413-Y417 HydrophobicContact CD2-CE2 4.2Å; L413-Y417 WeakPolarHBondContact O-CB 3.42Å; L413-Y417 WeakPolarHBondContact O-CD2 3.35Å; L413-Y417 PolarHBondContact O-N 3.08Å; I415-Y417 PolarHBondContact O-N 3.18Å; Y417-L419 VanDerWaalsContact C-N 3.35Å; Y417-N420 PolarHBondContact O-N 3.1Å; Y417-L421 WeakPolarHBondContact O-CB 3.34Å; Y417-L421 VanDerWaalsContact O-CG 3.22Å; Y417-L421 WeakPolarHBondContact O-CG 3.48Å; Y417-L421 PolarHBondContact O-N 3.35Å
418T91.6Very high90.8Very high84 Ų8461.1 Ų61.152%0.51532%0.32SS..Hα-helixtrans-61.7-45.5173.1-60.40000110.7A414 I415 T422A414-T418 VanDerWaalsContact O-CB 3.28Å; A414-T418 WeakPolarHBondContact O-CB 3.29Å; A414-T418 PolarHBondContact O-N 3.24Å; A414-T418 PolarHBondContact O-OG1 3.07Å; I415-T418 PolarHBondContact O-N 2.98Å; T418-T422 VanDerWaalsContact O-CB 3.31Å; T418-T422 WeakPolarHBondContact O-CB 3.44Å; T418-T422 PolarHBondContact O-N 3.48Å; T418-T422 PolarHBondContact O-OG1 3.11Å
419L88.8Confident90.6Very high49 Ų4967.9 Ų67.926%0.25735%0.351SS..Hα-helixtrans-63.6-44.4175.6-72.5172.5000111.5I415 Y416 Y417 T422 Y423 L629 L630I415-L419 HydrophobicContact CG2-CD1 4.12Å; I415-L419 HydrophobicContact CG2-CG 4.46Å; I415-L419 WeakPolarHBondContact O-CG 3.41Å; I415-L419 PolarHBondContact O-N 3.45Å; Y416-L419 PolarHBondContact O-N 3.35Å; Y417-L419 VanDerWaalsContact C-N 3.35Å; L419-T422 PolarHBondContact O-N 3.06Å; L419-Y423 WeakPolarHBondContact O-CB 3.45Å; L419-Y423 PolarHBondContact O-N 3.47Å; L419-L629 HydrophobicContact CD1-CB 4.19Å; L419-L630 HydrophobicContact CD1-CD2 4.25Å
420N86.8Confident90.2Very high27 Ų2773.7 Ų73.714%0.14438%0.375CS..Hα-helixtrans-59.8-48.9177.7-174.7-92.6000112.1Y416 Y417 Y423 H424Y416-N420 WeakPolarHBondContact O-CB 3.37Å; Y416-N420 PolarHBondContact O-N 3.31Å; Y417-N420 PolarHBondContact O-N 3.1Å; N420-Y423 WeakPolarHBondContact O-CB 3.38Å; N420-Y423 PolarHBondContact O-N 2.94Å; N420-H424 PolarHBondContact O-CD2 3.36Å; N420-H424 PolarHBondContact O-N 3.16Å; N420-H424 PolarHBondContact OD1-CD2 3.04Å
421L87.9Confident89.9Confident93 Ų9371 Ų7149%0.48737%0.365SS..Hα-helixtrans-64.4-41.8177.8-70.8171.5000111.9Y417 Y423 H424 H425Y417-L421 WeakPolarHBondContact O-CB 3.34Å; Y417-L421 VanDerWaalsContact O-CG 3.22Å; Y417-L421 WeakPolarHBondContact O-CG 3.48Å; Y417-L421 PolarHBondContact O-N 3.35Å; L421-Y423 VanDerWaalsContact C-N 3.3Å; L421-Y423 PolarHBondContact O-N 3.16Å; L421-H424 PolarHBondContact O-N 2.99Å; L421-H425 WeakPolarHBondContact O-CB 3.46Å; L421-H425 PolarHBondContact O-CD2 3.31Å; L421-H425 PolarHBondContact O-N 3.33Å
422T88.6Confident89.5Confident49 Ų4969.7 Ų69.730%0.30136%0.357SS..Hα-helixtrans-61.3-42.4176.1-56.20000110.7T418 L419 C426 F427T418-T422 VanDerWaalsContact O-CB 3.31Å; T418-T422 WeakPolarHBondContact O-CB 3.44Å; T418-T422 PolarHBondContact O-N 3.48Å; T418-T422 PolarHBondContact O-OG1 3.11Å; L419-T422 PolarHBondContact O-N 3.06Å; T422-C426 HydrophobicContact CG2-CB 3.96Å; T422-C426 CarbonylContact O-C 3.51Å; T422-C426 WeakPolarHBondContact O-CA 3.41Å; T422-C426 WeakPolarHBondContact O-CB 3.48Å; T422-C426 PolarHBondContact O-N 3.38Å; T422-F427 HydrophobicContact CG2-CD1 4.08Å; T422-F427 HydrophobicContact CG2-CE1 3.61Å; T422-F427 HydrophobicContact CG2-CZ 4.23Å; T422-F427 PolarHBondContact O-N 3.44Å
423Y85.5Confident89Confident10 Ų1075.1 Ų75.14%0.03938%0.383CS..Hα-helixtrans-63-46176.2167.9-84000112.5L419 N420 L421 F427 Q432 F435 K436 F634L419-Y423 WeakPolarHBondContact O-CB 3.45Å; L419-Y423 PolarHBondContact O-N 3.47Å; N420-Y423 WeakPolarHBondContact O-CB 3.38Å; N420-Y423 PolarHBondContact O-N 2.94Å; L421-Y423 VanDerWaalsContact C-N 3.3Å; L421-Y423 PolarHBondContact O-N 3.16Å; Y423-F427 AromaticContact CD2-CD2 3.92Å; Y423-F427 HydrophobicContact CD2-CD2 3.92Å; Y423-F427 HydrophobicContact CD2-CE2 4.42Å; Y423-F427 HydrophobicContact CG-CD2 4.39Å; Y423-F427 WeakPolarHBondContact O-CB 3.44Å; Y423-Q432 HydrophobicContact CD2-CB 4.26Å; Y423-Q432 HydrophobicContact CD2-CG 3.95Å; Y423-Q432 HydrophobicContact CE1-CG 4.35Å; Y423-Q432 HydrophobicContact CE2-CB 3.54Å; Y423-Q432 HydrophobicContact CE2-CG 3.61Å; Y423-Q432 HydrophobicContact CG-CG 4.46Å; Y423-Q432 PolarHBondContact O-NE2 2.88Å; Y423-F435 HydrophobicContact CD2-CB 4.23Å; Y423-F435 AromaticContact CD2-CD1 3.99Å; Y423-F435 HydrophobicContact CD2-CD1 3.99Å; Y423-F435 HydrophobicContact CD2-CG 4.24Å; Y423-F435 HydrophobicContact CE2-CB 4.49Å; Y423-F435 HydrophobicContact CE2-CD1 4.43Å; Y423-K436 WeakPolarHBondContact OH-CE 3.41Å; Y423-F634 HydrophobicContact CD1-CD1 4.42Å; Y423-F634 AromaticContact CD1-CE1 3.31Å; Y423-F634 HydrophobicContact CD1-CE1 3.31Å; Y423-F634 AromaticContact CD1-CE2 4Å; Y423-F634 HydrophobicContact CD1-CE2 4Å; Y423-F634 AromaticContact CD1-CZ 3.07Å; Y423-F634 HydrophobicContact CD1-CZ 3.07Å; Y423-F634 HydrophobicContact CD2-CD2 4.43Å; Y423-F634 HydrophobicContact CD2-CE1 4.27Å; Y423-F634 AromaticContact CD2-CE2 3.44Å; Y423-F634 HydrophobicContact CD2-CE2 3.44Å; Y423-F634 VanDerWaalsContact CD2-CE2 3.44Å; Y423-F634 AromaticContact CD2-CZ 3.4Å; Y423-F634 HydrophobicContact CD2-CZ 3.4Å; Y423-F634 VanDerWaalsContact CD2-CZ 3.4Å; Y423-F634 AromaticContact CE1-CD1 4Å; Y423-F634 HydrophobicContact CE1-CD1 4Å; Y423-F634 AromaticContact CE1-CE1 3.26Å; Y423-F634 HydrophobicContact CE1-CE1 3.26Å; Y423-F634 HydrophobicContact CE1-CE2 4.16Å; Y423-F634 AromaticContact CE1-CZ 3.41Å; Y423-F634 HydrophobicContact CE1-CZ 3.41Å; Y423-F634 VanDerWaalsContact CE1-CZ 3.41Å; Y423-F634 HydrophobicContact CE2-CD2 4.18Å; Y423-F634 HydrophobicContact CE2-CE1 4.21Å; Y423-F634 AromaticContact CE2-CE2 3.6Å; Y423-F634 HydrophobicContact CE2-CE2 3.6Å; Y423-F634 AromaticContact CE2-CZ 3.68Å; Y423-F634 HydrophobicContact CE2-CZ 3.68Å; Y423-F634 AromaticContact CG-CE1 3.86Å; Y423-F634 HydrophobicContact CG-CE1 3.86Å; Y423-F634 AromaticContact CG-CE2 3.66Å; Y423-F634 HydrophobicContact CG-CE2 3.66Å; Y423-F634 AromaticContact CG-CZ 3.09Å; Y423-F634 HydrophobicContact CG-CZ 3.09Å; Y423-F634 AromaticContact CZ-CE1 3.74Å; Y423-F634 AromaticContact CZ-CE2 3.97Å; Y423-F634 AromaticContact CZ-CZ 3.7Å
424H84.6Confident88.5Confident77 Ų7777.8 Ų77.836%0.35640%0.397SS..Hα-helixtrans-76.9-32.4-175.6-77.3-66.9000113.5N420 L421 F634N420-H424 PolarHBondContact O-CD2 3.36Å; N420-H424 PolarHBondContact O-N 3.16Å; N420-H424 PolarHBondContact OD1-CD2 3.04Å; L421-H424 PolarHBondContact O-N 2.99Å; H424-F634 AromaticContact NE2-CE1 3.82Å
425H87.9Confident88Confident149 Ų14977 Ų7769%0.6939%0.385SS*.Hα-helixtrans-113.8-19.9-170.4-60-60.6000114.9L421L421-H425 WeakPolarHBondContact O-CB 3.46Å; L421-H425 PolarHBondContact O-CD2 3.31Å; L421-H425 PolarHBondContact O-N 3.33Å
426C90.7Very high87.4Confident90 Ų9077.9 Ų77.961%0.60839%0.386SS*.THydrogen-bonded Turntrans-113.4-27.4-176.8-53.70000113.3T422T422-C426 HydrophobicContact CG2-CB 3.96Å; T422-C426 CarbonylContact O-C 3.51Å; T422-C426 WeakPolarHBondContact O-CA 3.41Å; T422-C426 WeakPolarHBondContact O-CB 3.48Å; T422-C426 PolarHBondContact O-N 3.38Å
427F88.1Confident86.8Confident62 Ų6280 Ų8027%0.27241%0.405SS..  trans-80.4136-178.6-72.41.5000112.4T422 Y423 Q431 Q432 F435T422-F427 HydrophobicContact CG2-CD1 4.08Å; T422-F427 HydrophobicContact CG2-CE1 3.61Å; T422-F427 HydrophobicContact CG2-CZ 4.23Å; T422-F427 PolarHBondContact O-N 3.44Å; Y423-F427 AromaticContact CD2-CD2 3.92Å; Y423-F427 HydrophobicContact CD2-CD2 3.92Å; Y423-F427 HydrophobicContact CD2-CE2 4.42Å; Y423-F427 HydrophobicContact CG-CD2 4.39Å; Y423-F427 WeakPolarHBondContact O-CB 3.44Å; F427-Q431 HydrophobicContact CB-CB 3.83Å; F427-Q431 HydrophobicContact CD1-CB 4.48Å; F427-Q431 HydrophobicContact CD2-CB 4.22Å; F427-Q431 HydrophobicContact CG-CB 3.95Å; F427-Q432 HydrophobicContact CB-CG 3.68Å; F427-F435 HydrophobicContact CD2-CB 4.29Å; F427-F435 HydrophobicContact CE2-CB 3.96Å; F427-F435 AromaticContact CE2-CD2 3.72Å; F427-F435 HydrophobicContact CE2-CD2 3.72Å; F427-F435 HydrophobicContact CE2-CE2 4.49Å; F427-F435 AromaticContact CE2-CG 3.97Å; F427-F435 HydrophobicContact CE2-CG 3.97Å; F427-F435 HydrophobicContact CZ-CD2 4.39Å
428T92.6Very high86.4Confident80 Ų8077.7 Ų77.749%0.49140%0.399SS..  trans-68.1161.1164.961.20000110.7K430 Q431 Q432T428-K430 PolarHBondContact O-N 2.78Å; T428-Q431 WeakPolarHBondContact O-CA 3.44Å; T428-Q431 WeakPolarHBondContact O-CB 3.14Å; T428-Q431 PolarHBondContact O-N 2.82Å; T428-Q431 WeakPolarHBondContact OG1-CG 3.1Å; T428-Q431 PolarHBondContact OG1-N 3.38Å; T428-Q431 PolarHBondContact OG1-OE1 3.01Å; T428-Q431 VanDerWaalsContact OG1-OE1 3.04Å; T428-Q432 WeakPolarHBondContact O-CG 3.47Å; T428-Q432 PolarHBondContact O-N 2.8Å
429E87Confident86Confident153 Ų15373.9 Ų73.972%0.71538%0.376SS*.Hα-helixtrans-53.9-40.9179.2-64.2-174.1166.800112.8Q432 Q433E429-Q432 PolarHBondContact O-N 3.28Å; E429-Q433 WeakPolarHBondContact O-CG 3.28Å; E429-Q433 PolarHBondContact O-N 2.99Å
430K87.8Confident85.5Confident151 Ų15174.3 Ų74.366%0.65738%0.381SS*.Hα-helixtrans-62.9-42.7175.4-173.8174.6-178.3176.20112T428 Q433 N434T428-K430 PolarHBondContact O-N 2.78Å; K430-Q433 PolarHBondContact O-N 3.42Å; K430-N434 VanDerWaalsContact O-CG 3.32Å; K430-N434 PolarHBondContact O-N 3.47Å; K430-N434 PolarHBondContact O-OD1 3.09Å
431Q88.5Confident85.1Confident91 Ų9173.9 Ų73.943%0.42538%0.378SS..Hα-helixtrans-66.8-37.9176.6-73.5168.8-38.700112F427 T428 N434 F435F427-Q431 HydrophobicContact CB-CB 3.83Å; F427-Q431 HydrophobicContact CD1-CB 4.48Å; F427-Q431 HydrophobicContact CD2-CB 4.22Å; F427-Q431 HydrophobicContact CG-CB 3.95Å; T428-Q431 WeakPolarHBondContact O-CA 3.44Å; T428-Q431 WeakPolarHBondContact O-CB 3.14Å; T428-Q431 PolarHBondContact O-N 2.82Å; T428-Q431 WeakPolarHBondContact OG1-CG 3.1Å; T428-Q431 PolarHBondContact OG1-N 3.38Å; T428-Q431 PolarHBondContact OG1-OE1 3.01Å; T428-Q431 VanDerWaalsContact OG1-OE1 3.04Å; Q431-N434 PolarHBondContact O-N 3.26Å; Q431-F435 WeakPolarHBondContact O-CB 3.41Å; Q431-F435 PolarHBondContact O-N 2.96Å
432Q85.9Confident84.9Confident42 Ų4270.9 Ų70.920%0.19636%0.362CS..Hα-helixtrans-63.2-42.5174.6-69.9-177.8-4.200111.8Y423 F427 T428 E429 F435 K436Y423-Q432 HydrophobicContact CD2-CB 4.26Å; Y423-Q432 HydrophobicContact CD2-CG 3.95Å; Y423-Q432 HydrophobicContact CE1-CG 4.35Å; Y423-Q432 HydrophobicContact CE2-CB 3.54Å; Y423-Q432 HydrophobicContact CE2-CG 3.61Å; Y423-Q432 HydrophobicContact CG-CG 4.46Å; Y423-Q432 PolarHBondContact O-NE2 2.88Å; F427-Q432 HydrophobicContact CB-CG 3.68Å; T428-Q432 WeakPolarHBondContact O-CG 3.47Å; T428-Q432 PolarHBondContact O-N 2.8Å; E429-Q432 PolarHBondContact O-N 3.28Å; Q432-F435 PolarHBondContact O-N 3.17Å; Q432-K436 WeakPolarHBondContact O-CG 3.45Å; Q432-K436 PolarHBondContact O-N 3.38Å
433Q82.4Confident84.6Confident126 Ų12673 Ų7359%0.58937%0.369SS*.Hα-helixtrans-60.8-46.7174.6-72.1172.23.200111.6E429 K430 F435 K436 A437E429-Q433 WeakPolarHBondContact O-CG 3.28Å; E429-Q433 PolarHBondContact O-N 2.99Å; K430-Q433 PolarHBondContact O-N 3.42Å; Q433-F435 VanDerWaalsContact C-N 3.34Å; Q433-F435 PolarHBondContact O-N 2.77Å; Q433-K436 WeakPolarHBondContact O-CB 2.96Å; Q433-K436 PolarHBondContact O-N 3.22Å; Q433-A437 PolarHBondContact O-N 3.48Å; Q433-A437 VanDerWaalsContact O-N 3.11Å
434N82.7Confident84.1Confident93 Ų9377.4 Ų77.450%0.49739%0.389SS..Hα-helixtrans-60.2-44175.7-69.7-4.6000111.7K430 Q431 K436 A437 V438K430-N434 VanDerWaalsContact O-CG 3.32Å; K430-N434 PolarHBondContact O-N 3.47Å; K430-N434 PolarHBondContact O-OD1 3.09Å; Q431-N434 PolarHBondContact O-N 3.26Å; N434-K436 VanDerWaalsContact C-N 3.33Å; N434-K436 PolarHBondContact O-N 3.13Å; N434-A437 WeakPolarHBondContact O-CB 3.44Å; N434-A437 PolarHBondContact O-N 3.09Å; N434-V438 WeakPolarHBondContact O-CG2 3.39Å; N434-V438 PolarHBondContact O-N 3.41Å
435F84.9Confident83.7Confident27 Ų2773.8 Ų73.812%0.11837%0.372CS..Hα-helixtrans-64.7-36.5178.5-168.8-84000112.2Y423 F427 Q431 Q432 Q433 A437 V438 S439 L630 Q633 F634Y423-F435 HydrophobicContact CD2-CB 4.23Å; Y423-F435 AromaticContact CD2-CD1 3.99Å; Y423-F435 HydrophobicContact CD2-CD1 3.99Å; Y423-F435 HydrophobicContact CD2-CG 4.24Å; Y423-F435 HydrophobicContact CE2-CB 4.49Å; Y423-F435 HydrophobicContact CE2-CD1 4.43Å; F427-F435 HydrophobicContact CD2-CB 4.29Å; F427-F435 HydrophobicContact CE2-CB 3.96Å; F427-F435 AromaticContact CE2-CD2 3.72Å; F427-F435 HydrophobicContact CE2-CD2 3.72Å; F427-F435 HydrophobicContact CE2-CE2 4.49Å; F427-F435 AromaticContact CE2-CG 3.97Å; F427-F435 HydrophobicContact CE2-CG 3.97Å; F427-F435 HydrophobicContact CZ-CD2 4.39Å; Q431-F435 WeakPolarHBondContact O-CB 3.41Å; Q431-F435 PolarHBondContact O-N 2.96Å; Q432-F435 PolarHBondContact O-N 3.17Å; Q433-F435 VanDerWaalsContact C-N 3.34Å; Q433-F435 PolarHBondContact O-N 2.77Å; F435-A437 VanDerWaalsContact C-N 3.35Å; F435-V438 WeakPolarHBondContact O-CB 3.38Å; F435-V438 PolarHBondContact O-N 3.13Å; F435-S439 WeakPolarHBondContact O-CB 3.35Å; F435-S439 PolarHBondContact O-N 3.1Å; F435-L630 HydrophobicContact CE2-CD2 4.14Å; F435-L630 HydrophobicContact CZ-CD2 4.05Å; F435-Q633 HydrophobicContact CE1-CB 4.05Å; F435-Q633 HydrophobicContact CE1-CG 4.06Å; F435-Q633 HydrophobicContact CZ-CG 4.21Å; F435-F634 AromaticContact CD1-CD2 3.9Å; F435-F634 HydrophobicContact CD1-CD2 3.9Å; F435-F634 AromaticContact CD1-CE2 3.41Å; F435-F634 HydrophobicContact CD1-CE2 3.41Å; F435-F634 VanDerWaalsContact CD1-CE2 3.41Å; F435-F634 AromaticContact CE1-CD2 3.94Å; F435-F634 HydrophobicContact CE1-CD2 3.94Å; F435-F634 AromaticContact CE1-CE2 3.38Å; F435-F634 HydrophobicContact CE1-CE2 3.38Å; F435-F634 HydrophobicContact CE1-CZ 4.47Å
436K82.1Confident83.4Confident94 Ų9467.2 Ų67.241%0.40934%0.342SS..Hα-helixtrans-61.4-42.7172.9-75.3176.8-174.7176.30111.9Y423 Q432 Q433 N434 V438 S439 V440Y423-K436 WeakPolarHBondContact OH-CE 3.41Å; Q432-K436 WeakPolarHBondContact O-CG 3.45Å; Q432-K436 PolarHBondContact O-N 3.38Å; Q433-K436 WeakPolarHBondContact O-CB 2.96Å; Q433-K436 PolarHBondContact O-N 3.22Å; N434-K436 VanDerWaalsContact C-N 3.33Å; N434-K436 PolarHBondContact O-N 3.13Å; K436-V438 VanDerWaalsContact C-N 3.34Å; K436-V438 PolarHBondContact O-N 3.47Å; K436-S439 WeakPolarHBondContact O-CB 3.49Å; K436-S439 PolarHBondContact O-N 2.73Å; K436-V440 WeakPolarHBondContact O-CG2 3.43Å; K436-V440 PolarHBondContact O-N 3.14Å
437A78.6Confident82.7Confident51 Ų5170.7 Ų70.742%0.42135%0.349SS..Hα-helixtrans-60.4-44.8175.200000111.4I269 Q433 N434 F435 S439 V440 L441I269-A437 HydrophobicContact CD1-CB 4.17Å; Q433-A437 PolarHBondContact O-N 3.48Å; Q433-A437 VanDerWaalsContact O-N 3.11Å; N434-A437 WeakPolarHBondContact O-CB 3.44Å; N434-A437 PolarHBondContact O-N 3.09Å; F435-A437 VanDerWaalsContact C-N 3.35Å; A437-S439 PolarHBondContact O-N 3.48Å; A437-V440 PolarHBondContact O-N 2.98Å; A437-L441 PolarHBondContact O-N 3.48Å
438V81Confident82.1Confident33 Ų3369 Ų6920%0.234%0.343CS..Hα-helixtrans-58.8-44.2173.3174.70000111.8I269 N434 F435 K436 L441 F442I269-V438 HydrophobicContact CD1-CB 4.29Å; I269-V438 HydrophobicContact CD1-CG2 3.46Å; I269-V438 VanDerWaalsContact CD1-CG2 3.46Å; I269-V438 HydrophobicContact CG1-CG2 4.31Å; N434-V438 WeakPolarHBondContact O-CG2 3.39Å; N434-V438 PolarHBondContact O-N 3.41Å; F435-V438 WeakPolarHBondContact O-CB 3.38Å; F435-V438 PolarHBondContact O-N 3.13Å; K436-V438 VanDerWaalsContact C-N 3.34Å; K436-V438 PolarHBondContact O-N 3.47Å; V438-L441 WeakPolarHBondContact O-CB 3.29Å; V438-L441 PolarHBondContact O-N 3.18Å; V438-F442 HydrophobicContact CG1-CD2 3.49Å; V438-F442 VanDerWaalsContact CG1-CD2 3.49Å; V438-F442 HydrophobicContact CG1-CE2 3.33Å; V438-F442 VanDerWaalsContact O-CD2 3.23Å; V438-F442 WeakPolarHBondContact O-CD2 3.48Å; V438-F442 PolarHBondContact O-N 2.85Å
439S82.6Confident81.4Confident4 Ų465.7 Ų65.73%0.02832%0.322CS..Hα-helixtrans-60.6-47.6178.8-174.50000111.8F435 K436 A437 L441 F442 M443 L630 S631F435-S439 WeakPolarHBondContact O-CB 3.35Å; F435-S439 PolarHBondContact O-N 3.1Å; K436-S439 WeakPolarHBondContact O-CB 3.49Å; K436-S439 PolarHBondContact O-N 2.73Å; A437-S439 PolarHBondContact O-N 3.48Å; S439-L441 VanDerWaalsContact C-N 3.3Å; S439-L441 PolarHBondContact O-N 3.5Å; S439-F442 PolarHBondContact O-N 2.97Å; S439-M443 WeakPolarHBondContact O-CB 3.5Å; S439-M443 PolarHBondContact O-N 3.11Å; S439-L630 WeakPolarHBondContact CB-O 3.46Å; S439-L630 PolarHBondContact OG-O 3.32Å; S439-S631 WeakPolarHBondContact O-CA 3.46Å; S439-S631 WeakPolarHBondContact OG-CA 3.47Å; S439-S631 PolarHBondContact OG-O 3.19Å
440V79.9Confident81Confident58 Ų5859.2 Ų59.235%0.35229%0.293SS..Hα-helixtrans-62-40.5178.1171.70000111K436 A437 M443 K444K436-V440 WeakPolarHBondContact O-CG2 3.43Å; K436-V440 PolarHBondContact O-N 3.14Å; A437-V440 PolarHBondContact O-N 2.98Å; V440-M443 WeakPolarHBondContact O-CB 3.28Å; V440-M443 PolarHBondContact O-N 2.88Å; V440-K444 PolarHBondContact O-N 3.18Å
441L78.7Confident80.9Confident18 Ų1852.3 Ų52.39%0.09426%0.264CS..Hα-helixtrans-60.1-52176.1174.363.2000111.7I269 E270 I276 A437 V438 S439 M443 K444 G445I269-L441 HydrophobicContact CB-CD2 3.92Å; I269-L441 HydrophobicContact CG2-CD2 3.81Å; E270-L441 HydrophobicContact CG-CD1 3.64Å; E270-L441 HydrophobicContact CG-CD2 3.7Å; E270-L441 HydrophobicContact CG-CG 4.23Å; I276-L441 HydrophobicContact CD1-CD1 4Å; I276-L441 HydrophobicContact CD1-CG 3.86Å; I276-L441 WeakPolarHBondContact CD1-O 3.4Å; A437-L441 PolarHBondContact O-N 3.48Å; V438-L441 WeakPolarHBondContact O-CB 3.29Å; V438-L441 PolarHBondContact O-N 3.18Å; S439-L441 VanDerWaalsContact C-N 3.3Å; S439-L441 PolarHBondContact O-N 3.5Å; L441-M443 VanDerWaalsContact C-N 3.26Å; L441-M443 PolarHBondContact O-N 3.12Å; L441-K444 PolarHBondContact O-N 3.18Å; L441-G445 PolarHBondContact O-N 2.86Å; L441-G445 VanDerWaalsContact O-N 3.1Å
442F83Confident80.8Confident31 Ų3150.8 Ų50.814%0.13626%0.261CS..Hα-helixtrans-68.1-25.5-179.9-73.4-56.3000113.4I276 V438 S439 G445 N446 L627 L630I276-F442 HydrophobicContact CD1-CD1 3.82Å; I276-F442 HydrophobicContact CD1-CE1 4.31Å; I276-F442 HydrophobicContact CG1-CD1 3.82Å; I276-F442 HydrophobicContact CG1-CE1 4.04Å; V438-F442 HydrophobicContact CG1-CD2 3.49Å; V438-F442 VanDerWaalsContact CG1-CD2 3.49Å; V438-F442 HydrophobicContact CG1-CE2 3.33Å; V438-F442 VanDerWaalsContact O-CD2 3.23Å; V438-F442 WeakPolarHBondContact O-CD2 3.48Å; V438-F442 PolarHBondContact O-N 2.85Å; S439-F442 PolarHBondContact O-N 2.97Å; F442-G445 WeakPolarHBondContact O-CA 3.46Å; F442-G445 PolarHBondContact O-N 3.39Å; F442-G445 VanDerWaalsContact O-N 3.17Å; F442-N446 PolarHBondContact O-N 3.06Å; F442-L627 HydrophobicContact CB-CD2 4.34Å; F442-L627 HydrophobicContact CD1-CD2 3.3Å; F442-L627 HydrophobicContact CE1-CD2 3.79Å; F442-L627 HydrophobicContact CG-CD2 4.07Å; F442-L630 HydrophobicContact CB-CB 4.41Å; F442-L630 HydrophobicContact CD2-CB 3.71Å; F442-L630 HydrophobicContact CD2-CD1 3.6Å; F442-L630 HydrophobicContact CD2-CG 4.3Å; F442-L630 HydrophobicContact CE2-CB 4.33Å; F442-L630 HydrophobicContact CE2-CD1 3.35Å; F442-L630 HydrophobicContact CE2-CG 4.46Å; F442-L630 HydrophobicContact CG-CB 4.32Å; F442-L630 HydrophobicContact CG-CD1 4.39Å; F442-L630 HydrophobicContact CZ-CD1 3.97Å
443M81.3Confident80.8Confident92 Ų9252 Ų5245%0.45327%0.265SS..Hα-helixtrans-61.9-47.1173.1-170179.972.200110.8S439 V440 L441 G445 N446 S631S439-M443 WeakPolarHBondContact O-CB 3.5Å; S439-M443 PolarHBondContact O-N 3.11Å; V440-M443 WeakPolarHBondContact O-CB 3.28Å; V440-M443 PolarHBondContact O-N 2.88Å; L441-M443 VanDerWaalsContact C-N 3.26Å; L441-M443 PolarHBondContact O-N 3.12Å; M443-G445 VanDerWaalsContact C-N 3.25Å; M443-G445 PolarHBondContact O-N 3.11Å; M443-N446 WeakPolarHBondContact O-CB 3.42Å; M443-N446 PolarHBondContact O-N 3.19Å; M443-N446 VanDerWaalsContact O-N 3.17Å; M443-S631 VanDerWaalsContact CA-CB 3.45Å
444K76.4Confident80.9Confident104 Ų10446 Ų4645%0.45224%0.238SC..Hα-helixtrans-61.9-34.9172.7-64176.4-177.3174.30111.7V440 L441 N446 L448V440-K444 PolarHBondContact O-N 3.18Å; L441-K444 PolarHBondContact O-N 3.18Å; K444-N446 VanDerWaalsContact C-N 3.31Å; K444-N446 PolarHBondContact O-N 3.17Å; K444-L448 WeakPolarHBondContact O-CD1 3.36Å
445G76.6Confident81.3Confident1 Ų141.7 Ų41.71%0.0121%0.214CC..Hα-helixtrans-63.4-34.9175.300000114I276 L441 F442 M443 L448I276-G445 VanDerWaalsContact CG2-CA 3.49Å; L441-G445 PolarHBondContact O-N 2.86Å; L441-G445 VanDerWaalsContact O-N 3.1Å; F442-G445 WeakPolarHBondContact O-CA 3.46Å; F442-G445 PolarHBondContact O-N 3.39Å; F442-G445 VanDerWaalsContact O-N 3.17Å; M443-G445 VanDerWaalsContact C-N 3.25Å; M443-G445 PolarHBondContact O-N 3.11Å; G445-L448 WeakPolarHBondContact O-CB 3.17Å; G445-L448 PolarHBondContact O-N 3.2Å
446N79.7Confident81.5Confident11 Ų1143.6 Ų43.66%0.05923%0.231CC..Hα-helixtrans-68.5-36.2-174.5-154.332.1000113.1F442 M443 K444 L448 I449 F624 C628F442-N446 PolarHBondContact O-N 3.06Å; M443-N446 WeakPolarHBondContact O-CB 3.42Å; M443-N446 PolarHBondContact O-N 3.19Å; M443-N446 VanDerWaalsContact O-N 3.17Å; K444-N446 VanDerWaalsContact C-N 3.31Å; K444-N446 PolarHBondContact O-N 3.17Å; N446-L448 PolarHBondContact O-N 3.35Å; N446-I449 PolarHBondContact O-N 3.41Å; N446-F624 VanDerWaalsContact CG-CE2 3.47Å; N446-F624 VanDerWaalsContact ND2-CE2 3.32Å; N446-F624 WeakPolarHBondContact ND2-CE2 3.33Å; N446-F624 WeakPolarHBondContact OD1-CD2 3.46Å; N446-F624 WeakPolarHBondContact OD1-CE2 3.3Å; N446-C628 PolarHBondContact ND2-SG 3.24Å
447E77.1Confident81.9Confident162 Ų16241 Ų4176%0.75722%0.22SC*.THydrogen-bonded Turntrans-64.9-17.5178.4-65.2179.2170.900113.1
448L74.7Confident82.6Confident27 Ų2738.6 Ų38.614%0.14120%0.2CC..THydrogen-bonded Turntrans-92.4-5.7-174.3-60.3160.7000113L74 I276 Q280 K444 G445 N446 P450L74-L448 HydrophobicContact CD2-CD2 4.17Å; I276-L448 HydrophobicContact CG2-CD1 4.21Å; Q280-L448 HydrophobicContact CG-CB 4.11Å; K444-L448 WeakPolarHBondContact O-CD1 3.36Å; G445-L448 WeakPolarHBondContact O-CB 3.17Å; G445-L448 PolarHBondContact O-N 3.2Å; N446-L448 PolarHBondContact O-N 3.35Å; L448-P450 WeakPolarHBondContact O-CD 3.44Å
449I78.1Confident83.2Confident10 Ų1038 Ų385%0.05120%0.196CC..  trans-100.6104.7175.8-49.2179.8000108.8I279 N446 I451 A620 L627I279-I449 HydrophobicContact CG2-CD1 3.76Å; I279-I449 HydrophobicContact CG2-CG1 4.49Å; N446-I449 PolarHBondContact O-N 3.41Å; I449-I451 VanDerWaalsContact C-N 3.29Å; I449-I451 HydrophobicContact CB-CG1 4.38Å; I449-I451 HydrophobicContact CG2-CD1 4.26Å; I449-I451 HydrophobicContact CG2-CG1 3.7Å; I449-I451 PolarHBondContact O-N 2.87Å; I449-A620 HydrophobicContact CG2-CB 4.37Å; I449-L627 HydrophobicContact CD1-CD1 3.68Å
450P79.1Confident83.7Confident18 Ų1840.8 Ų40.812%0.11721%0.211CC..  trans-85.766.1-17339-42.7000112.2T79 F283 Y284 L448 T452 F453 V454T79-P450 HydrophobicContact CG2-CB 3.43Å; T79-P450 VanDerWaalsContact CG2-CB 3.43Å; T79-P450 HydrophobicContact CG2-CG 3.47Å; T79-P450 VanDerWaalsContact CG2-CG 3.47Å; T79-P450 WeakPolarHBondContact OG1-CB 3.28Å; T79-P450 WeakPolarHBondContact OG1-CG 3.22Å; F283-P450 VanDerWaalsContact CE1-CD 3.41Å; F283-P450 HydrophobicContact CE1-CG 3.39Å; F283-P450 HydrophobicContact CZ-CG 3.59Å; Y284-P450 HydrophobicContact CE1-CG 4.2Å; Y284-P450 WeakPolarHBondContact OH-CD 3.36Å; Y284-P450 WeakPolarHBondContact OH-CG 3.48Å; L448-P450 WeakPolarHBondContact O-CD 3.44Å; P450-T452 VanDerWaalsContact C-N 3.32Å; P450-T452 PolarHBondContact O-N 3.42Å; P450-F453 HydrophobicContact CB-CD2 4.26Å; P450-F453 PolarHBondContact O-N 2.81Å; P450-V454 PolarHBondContact O-N 3.24Å
451I85Confident84.2Confident6 Ų638.7 Ų38.73%0.03120%0.197CC..Hα-helixtrans-63.5-38.4-170.4-62.7151.9000112.5I449 F453 V454 L455 V621 F624 Y657I449-I451 VanDerWaalsContact C-N 3.29Å; I449-I451 HydrophobicContact CB-CG1 4.38Å; I449-I451 HydrophobicContact CG2-CD1 4.26Å; I449-I451 HydrophobicContact CG2-CG1 3.7Å; I449-I451 PolarHBondContact O-N 2.87Å; I451-F453 PolarHBondContact O-N 3.15Å; I451-V454 PolarHBondContact O-N 3.12Å; I451-L455 HydrophobicContact CG2-CB 4.25Å; I451-L455 HydrophobicContact CG2-CD2 4.24Å; I451-L455 WeakPolarHBondContact O-CB 3.17Å; I451-L455 PolarHBondContact O-N 3.46Å; I451-V621 HydrophobicContact CG2-CG2 3.85Å; I451-F624 HydrophobicContact CD1-CB 3.1Å; I451-F624 HydrophobicContact CD1-CD1 3.61Å; I451-F624 HydrophobicContact CD1-CD2 3Å; I451-F624 HydrophobicContact CD1-CE1 4.22Å; I451-F624 HydrophobicContact CD1-CE2 3.69Å; I451-F624 HydrophobicContact CD1-CG 2.95Å; I451-F624 HydrophobicContact CD1-CZ 4.25Å; I451-F624 HydrophobicContact CG1-CB 4.18Å; I451-F624 HydrophobicContact CG1-CD2 4.38Å; I451-F624 HydrophobicContact CG1-CG 4.36Å; I451-Y657 HydrophobicContact CD1-CD2 4.45Å; I451-Y657 HydrophobicContact CG2-CD1 4.31Å; I451-Y657 HydrophobicContact CG2-CD2 4.3Å; I451-Y657 HydrophobicContact CG2-CG 4.08Å
452T87.4Confident84.9Confident59 Ų5937.9 Ų37.936%0.36219%0.193SC..Hα-helixtrans-52.2-46.4-178.149.50000110.8P450 S456 Y657P450-T452 VanDerWaalsContact C-N 3.32Å; P450-T452 PolarHBondContact O-N 3.42Å; T452-S456 WeakPolarHBondContact O-CB 3.24Å; T452-S456 PolarHBondContact O-N 3.4Å; T452-S456 VanDerWaalsContact O-N 3.07Å; T452-S456 PolarHBondContact O-OG 3.19Å; T452-Y657 HydrophobicContact CG2-CE1 3.84Å; T452-Y657 WeakPolarHBondContact CG2-OH 3.42Å
453F84.7Confident85.4Confident67 Ų6738.1 Ų38.129%0.29420%0.2SC..Hα-helixtrans-69.7-54.3-179.9-64.9-77.8000112T79 F80 P450 I451 L455 S456 F457T79-F453 HydrophobicContact CG2-CB 3.49Å; T79-F453 VanDerWaalsContact CG2-CB 3.49Å; T79-F453 HydrophobicContact CG2-CD2 3.69Å; T79-F453 HydrophobicContact CG2-CG 3.72Å; F80-F453 HydrophobicContact CD1-CD1 4.41Å; F80-F453 AromaticContact CD1-CE1 3.97Å; F80-F453 HydrophobicContact CD1-CE1 3.97Å; F80-F453 HydrophobicContact CE1-CD1 4.1Å; F80-F453 AromaticContact CE1-CE1 3.24Å; F80-F453 HydrophobicContact CE1-CE1 3.24Å; F80-F453 AromaticContact CE1-CZ 3.65Å; F80-F453 HydrophobicContact CE1-CZ 3.65Å; F80-F453 HydrophobicContact CE2-CE1 4.07Å; F80-F453 HydrophobicContact CE2-CE2 4.19Å; F80-F453 AromaticContact CE2-CZ 3.65Å; F80-F453 HydrophobicContact CE2-CZ 3.65Å; F80-F453 HydrophobicContact CZ-CD1 4.38Å; F80-F453 AromaticContact CZ-CE1 3.32Å; F80-F453 HydrophobicContact CZ-CE1 3.32Å; F80-F453 HydrophobicContact CZ-CE2 4.12Å; F80-F453 AromaticContact CZ-CZ 3.15Å; F80-F453 HydrophobicContact CZ-CZ 3.15Å; P450-F453 HydrophobicContact CB-CD2 4.26Å; P450-F453 PolarHBondContact O-N 2.81Å; I451-F453 PolarHBondContact O-N 3.15Å; F453-L455 VanDerWaalsContact C-N 3.33Å; F453-L455 PolarHBondContact O-N 3.48Å; F453-S456 PolarHBondContact O-N 3.4Å; F453-F457 WeakPolarHBondContact O-CD2 3.17Å; F453-F457 PolarHBondContact O-N 3.4Å
454V84.8Confident86Confident1 Ų139.1 Ų39.11%0.00620%0.202CC..Hα-helixtrans-59.9-45.4-176.7165.30000112.1F283 W287 P450 I451 F458 V617F283-V454 HydrophobicContact CE1-CG2 4.23Å; F283-V454 HydrophobicContact CE2-CB 3.95Å; F283-V454 HydrophobicContact CE2-CG1 4.04Å; F283-V454 HydrophobicContact CE2-CG2 3.45Å; F283-V454 VanDerWaalsContact CE2-CG2 3.45Å; F283-V454 HydrophobicContact CZ-CB 3.99Å; F283-V454 HydrophobicContact CZ-CG2 3.16Å; W287-V454 HydrophobicContact CD2-CG2 3.78Å; W287-V454 HydrophobicContact CE3-CG2 3.49Å; W287-V454 VanDerWaalsContact CE3-CG2 3.49Å; W287-V454 HydrophobicContact CH2-CB 4.34Å; W287-V454 HydrophobicContact CH2-CG2 3.24Å; W287-V454 HydrophobicContact CZ2-CB 4.39Å; W287-V454 HydrophobicContact CZ2-CG2 3.51Å; W287-V454 HydrophobicContact CZ3-CG2 3.23Å; P450-V454 PolarHBondContact O-N 3.24Å; I451-V454 PolarHBondContact O-N 3.12Å; V454-F458 WeakPolarHBondContact O-CB 3.44Å; V454-F458 PolarHBondContact O-N 2.83Å; V454-V617 HydrophobicContact CG1-CB 4.12Å; V454-V617 HydrophobicContact CG1-CG1 4.23Å; V454-V617 HydrophobicContact CG1-CG2 3.55Å
455L92.2Very high86.8Confident2 Ų235.1 Ų35.11%0.0118%0.184CC..Hα-helixtrans-66.3-41.6179.4-173.257.8000111.4I451 F453 F458 V459 V617 V621 Y657 L660 L661I451-L455 HydrophobicContact CG2-CB 4.25Å; I451-L455 HydrophobicContact CG2-CD2 4.24Å; I451-L455 WeakPolarHBondContact O-CB 3.17Å; I451-L455 PolarHBondContact O-N 3.46Å; F453-L455 VanDerWaalsContact C-N 3.33Å; F453-L455 PolarHBondContact O-N 3.48Å; L455-F458 PolarHBondContact O-N 3.36Å; L455-V459 HydrophobicContact CD1-CG2 4.1Å; L455-V459 HydrophobicContact CG-CG2 4.3Å; L455-V459 WeakPolarHBondContact O-CB 3.18Å; L455-V459 WeakPolarHBondContact O-CG2 3.35Å; L455-V459 PolarHBondContact O-N 2.95Å; L455-V617 HydrophobicContact CD1-CG1 3.85Å; L455-V621 HydrophobicContact CD1-CG2 4.31Å; L455-V621 HydrophobicContact CD2-CG2 4.23Å; L455-Y657 HydrophobicContact CD2-CD1 4.39Å; L455-Y657 WeakPolarHBondContact CD2-O 3.33Å; L455-L660 HydrophobicContact CD1-CB 4.39Å; L455-L660 HydrophobicContact CD2-CB 3.6Å; L455-L660 HydrophobicContact CD2-CD1 4.18Å; L455-L660 HydrophobicContact CG-CB 3.93Å; L455-L661 HydrophobicContact CD1-CB 4.1Å; L455-L661 HydrophobicContact CD1-CD1 4.15Å
456S89.6Confident87.6Confident66 Ų6637.7 Ų37.746%0.46219%0.194SC..Hα-helixtrans-63.9-45.3178.9-62.20000112.2T452 F453 F458 V459 D460T452-S456 WeakPolarHBondContact O-CB 3.24Å; T452-S456 PolarHBondContact O-N 3.4Å; T452-S456 VanDerWaalsContact O-N 3.07Å; T452-S456 PolarHBondContact O-OG 3.19Å; F453-S456 PolarHBondContact O-N 3.4Å; S456-F458 VanDerWaalsContact C-N 3.34Å; S456-F458 PolarHBondContact O-N 3Å; S456-V459 PolarHBondContact O-N 3.48Å; S456-D460 WeakPolarHBondContact O-CB 3.38Å; S456-D460 PolarHBondContact O-N 3.33Å
457F89Confident88.2Confident40 Ų4044 Ų4418%0.17522%0.217CC..Hα-helixtrans-63.6-40.4176.8-78.1-68000111.9N87 W287 F453 Q461N87-F457 HydrophobicContact CB-CD1 4.03Å; N87-F457 HydrophobicContact CB-CE1 4.23Å; W287-F457 HydrophobicContact CH2-CD2 4.36Å; W287-F457 HydrophobicContact CZ2-CD2 4.36Å; F453-F457 WeakPolarHBondContact O-CD2 3.17Å; F453-F457 PolarHBondContact O-N 3.4Å; F457-Q461 WeakPolarHBondContact O-CG 3.22Å; F457-Q461 PolarHBondContact O-N 3.12Å; F457-Q461 VanDerWaalsContact O-N 3.14Å
458F93Very high88.9Confident0 Ų038.3 Ų38.30%019%0.19CC..Hα-helixtrans-64.7-49.4177.3-179.2-110.3000111.9F17 V454 L455 S456 D460 Q461 V462 V609 Y613 T614 V617 A664 L668F17-F458 HydrophobicContact CE2-CE1 4.47Å; V454-F458 WeakPolarHBondContact O-CB 3.44Å; V454-F458 PolarHBondContact O-N 2.83Å; L455-F458 PolarHBondContact O-N 3.36Å; S456-F458 VanDerWaalsContact C-N 3.34Å; S456-F458 PolarHBondContact O-N 3Å; F458-D460 VanDerWaalsContact C-N 3.33Å; F458-D460 PolarHBondContact O-N 3.5Å; F458-Q461 PolarHBondContact O-N 3.21Å; F458-V462 HydrophobicContact CD1-CG2 4.39Å; F458-V462 HydrophobicContact CD2-CG2 4.3Å; F458-V462 HydrophobicContact CE1-CG2 4.08Å; F458-V462 HydrophobicContact CE2-CG2 3.97Å; F458-V462 HydrophobicContact CZ-CG2 3.85Å; F458-V462 WeakPolarHBondContact O-CG2 3.2Å; F458-V462 PolarHBondContact O-N 2.87Å; F458-V609 HydrophobicContact CE2-CG1 4.14Å; F458-Y613 HydrophobicContact CB-CE2 4.26Å; F458-Y613 HydrophobicContact CD2-CD1 4.21Å; F458-Y613 HydrophobicContact CD2-CD2 4.01Å; F458-Y613 HydrophobicContact CD2-CE1 4.19Å; F458-Y613 AromaticContact CD2-CE2 3.97Å; F458-Y613 HydrophobicContact CD2-CE2 3.97Å; F458-Y613 HydrophobicContact CD2-CG 4.12Å; F458-Y613 HydrophobicContact CE2-CG 4.4Å; F458-T614 HydrophobicContact CZ-CG2 4.29Å; F458-V617 HydrophobicContact CB-CB 4.48Å; F458-V617 HydrophobicContact CB-CG1 4.13Å; F458-V617 HydrophobicContact CB-CG2 3.63Å; F458-V617 HydrophobicContact CD1-CB 4.3Å; F458-V617 HydrophobicContact CD1-CG1 3.84Å; F458-V617 HydrophobicContact CD1-CG2 4.21Å; F458-V617 HydrophobicContact CD2-CG2 3.83Å; F458-V617 HydrophobicContact CE1-CG1 4.47Å; F458-V617 HydrophobicContact CG-CB 4.23Å; F458-V617 HydrophobicContact CG-CG1 4.07Å; F458-V617 HydrophobicContact CG-CG2 3.63Å; F458-A664 HydrophobicContact CD1-CB 3.76Å; F458-A664 HydrophobicContact CE1-CB 3.56Å; F458-L668 HydrophobicContact CZ-CD1 4.29Å
459V94.2Very high89.8Confident22 Ų2237.3 Ų37.313%0.13318%0.184CC..Hα-helixtrans-58.3-44.7178.4171.60000110.9L455 S456 Q461 V462 A463 L660 A664L455-V459 HydrophobicContact CD1-CG2 4.1Å; L455-V459 HydrophobicContact CG-CG2 4.3Å; L455-V459 WeakPolarHBondContact O-CB 3.18Å; L455-V459 WeakPolarHBondContact O-CG2 3.35Å; L455-V459 PolarHBondContact O-N 2.95Å; S456-V459 PolarHBondContact O-N 3.48Å; V459-Q461 PolarHBondContact O-N 2.71Å; V459-V462 PolarHBondContact O-N 3.46Å; V459-A463 VanDerWaalsContact O-CB 3.27Å; V459-A463 WeakPolarHBondContact O-CB 3.24Å; V459-A463 PolarHBondContact O-N 3.35Å; V459-L660 HydrophobicContact CG2-CB 4.32Å; V459-L660 HydrophobicContact CG2-CD2 4.47Å; V459-A664 HydrophobicContact CG2-CB 3.96Å
460D92.2Very high90.4Very high62 Ų6240.1 Ų40.133%0.33220%0.196SC..Hα-helixtrans-59.6-45.4177.7174.863.8000112S456 F458 A463 K464S456-D460 WeakPolarHBondContact O-CB 3.38Å; S456-D460 PolarHBondContact O-N 3.33Å; F458-D460 VanDerWaalsContact C-N 3.33Å; F458-D460 PolarHBondContact O-N 3.5Å; D460-A463 PolarHBondContact O-N 2.89Å; D460-K464 WeakPolarHBondContact O-CG 3.37Å; D460-K464 PolarHBondContact O-N 2.87Å; D460-K464 WeakPolarHBondContact OD1-CE 3.3Å; D460-K464 IonicContact OD1-NZ 3.06Å; D460-K464 PolarHBondContact OD1-NZ 3.37Å; D460-K464 WeakPolarHBondContact OD2-CE 3.46Å; D460-K464 IonicContact OD2-NZ 2.67Å; D460-K464 PolarHBondContact OD2-NZ 3.48Å
461Q91.1Very high91.1Very high14 Ų1444.4 Ų44.47%0.06522%0.218CC..Hα-helixtrans-66.8-39.7179.3-71.7-61.4-16.500112.9N87 Y90 F457 F458 V459 R465N87-Q461 PolarHBondContact OD1-NE2 3.38Å; Y90-Q461 HydrophobicContact CD1-CB 4.21Å; Y90-Q461 VanDerWaalsContact CD1-CD 3.41Å; Y90-Q461 HydrophobicContact CD1-CG 3.83Å; Y90-Q461 HydrophobicContact CE1-CB 3.89Å; Y90-Q461 HydrophobicContact CE1-CG 4.01Å; F457-Q461 WeakPolarHBondContact O-CG 3.22Å; F457-Q461 PolarHBondContact O-N 3.12Å; F457-Q461 VanDerWaalsContact O-N 3.14Å; F458-Q461 PolarHBondContact O-N 3.21Å; V459-Q461 PolarHBondContact O-N 2.71Å; Q461-R465 WeakPolarHBondContact O-CB 3.49Å; Q461-R465 PolarHBondContact O-N 2.95Å; Q461-R465 VanDerWaalsContact O-N 3.12Å
462V93.9Very high91.5Very high1 Ų144.2 Ų44.21%0.00622%0.217CC..Hα-helixtrans-66.8-43.6175.3176.80000110.7F458 V459 K464 R465 W466 A664 L667 L668F458-V462 HydrophobicContact CD1-CG2 4.39Å; F458-V462 HydrophobicContact CD2-CG2 4.3Å; F458-V462 HydrophobicContact CE1-CG2 4.08Å; F458-V462 HydrophobicContact CE2-CG2 3.97Å; F458-V462 HydrophobicContact CZ-CG2 3.85Å; F458-V462 WeakPolarHBondContact O-CG2 3.2Å; F458-V462 PolarHBondContact O-N 2.87Å; V459-V462 PolarHBondContact O-N 3.46Å; V462-K464 PolarHBondContact O-N 2.88Å; V462-R465 WeakPolarHBondContact O-CB 3.29Å; V462-R465 PolarHBondContact O-N 2.81Å; V462-R465 VanDerWaalsContact O-N 3.15Å; V462-W466 WeakPolarHBondContact O-CB 3.38Å; V462-W466 PolarHBondContact O-N 2.73Å; V462-A664 WeakPolarHBondContact CG1-O 3.41Å; V462-L667 HydrophobicContact CG1-CB 3.63Å; V462-L668 HydrophobicContact CG1-CB 4.18Å
463A93.6Very high91.8Very high35 Ų3541.7 Ų41.729%0.28920%0.201SC..Hα-helixtrans-62.4-42.6178.300000112.6V459 D460 R465 W466 W467 L667V459-A463 VanDerWaalsContact O-CB 3.27Å; V459-A463 WeakPolarHBondContact O-CB 3.24Å; V459-A463 PolarHBondContact O-N 3.35Å; D460-A463 PolarHBondContact O-N 2.89Å; A463-R465 VanDerWaalsContact C-N 3.3Å; A463-R465 PolarHBondContact O-N 3.3Å; A463-W466 WeakPolarHBondContact O-CB 3.43Å; A463-W466 PolarHBondContact O-N 3.25Å; A463-W467 PolarHBondContact O-N 3.41Å; A463-L667 HydrophobicContact CB-CD1 4.13Å
464K94Very high92Very high113 Ų11338.7 Ų38.749%0.49119%0.188SC..Hα-helixtrans-60.5-40.4173.6-75.7169.7178.8163.60111.9D460 V462 K468D460-K464 WeakPolarHBondContact O-CG 3.37Å; D460-K464 PolarHBondContact O-N 2.87Å; D460-K464 WeakPolarHBondContact OD1-CE 3.3Å; D460-K464 IonicContact OD1-NZ 3.06Å; D460-K464 PolarHBondContact OD1-NZ 3.37Å; D460-K464 WeakPolarHBondContact OD2-CE 3.46Å; D460-K464 IonicContact OD2-NZ 2.67Å; D460-K464 PolarHBondContact OD2-NZ 3.48Å; V462-K464 PolarHBondContact O-N 2.88Å; K464-K468 WeakPolarHBondContact O-CB 3.13Å; K464-K468 PolarHBondContact O-N 3.26Å; K464-K468 VanDerWaalsContact O-N 3.16Å
465R92.7Very high92.3Very high21 Ų2143.4 Ų43.48%0.07921%0.206CC..Hα-helixtrans-65.4-46.4175.4-173.7-176179.793.73.6111.1Q461 V462 A463 W467 K468 I469 L604 V607Q461-R465 WeakPolarHBondContact O-CB 3.49Å; Q461-R465 PolarHBondContact O-N 2.95Å; Q461-R465 VanDerWaalsContact O-N 3.12Å; V462-R465 WeakPolarHBondContact O-CB 3.29Å; V462-R465 PolarHBondContact O-N 2.81Å; V462-R465 VanDerWaalsContact O-N 3.15Å; A463-R465 VanDerWaalsContact C-N 3.3Å; A463-R465 PolarHBondContact O-N 3.3Å; R465-W467 PolarHBondContact O-N 2.66Å; R465-K468 WeakPolarHBondContact O-CB 3.42Å; R465-K468 PolarHBondContact O-N 3.33Å; R465-K468 VanDerWaalsContact O-N 3.16Å; R465-I469 HydrophobicContact CG-CD1 4.18Å; R465-I469 WeakPolarHBondContact O-CG1 3.36Å; R465-I469 PolarHBondContact O-N 3.1Å; R465-L604 PolarHBondContact NH2-O 3.41Å; R465-V607 PolarHBondContact NH1-O 3.16Å; R465-V607 PolarHBondContact NH2-O 2.61Å
466W93.8Very high92.5Very high55 Ų5543.5 Ų43.521%0.20821%0.207CC..Hα-helixtrans-55-49.4177.3-178.793.7000112V462 A463 K468 I469 F470 L667 F678V462-W466 WeakPolarHBondContact O-CB 3.38Å; V462-W466 PolarHBondContact O-N 2.73Å; A463-W466 WeakPolarHBondContact O-CB 3.43Å; A463-W466 PolarHBondContact O-N 3.25Å; W466-K468 VanDerWaalsContact C-N 3.3Å; W466-K468 PolarHBondContact O-N 2.91Å; W466-I469 WeakPolarHBondContact O-CB 3.46Å; W466-I469 PolarHBondContact O-N 3.02Å; W466-I469 VanDerWaalsContact O-N 3.11Å; W466-F470 PolarHBondContact O-N 3.36Å; W466-L667 HydrophobicContact CB-CB 4.23Å; W466-L667 HydrophobicContact CB-CD2 4.38Å; W466-L667 HydrophobicContact CD2-CD2 3.85Å; W466-L667 HydrophobicContact CG-CB 4.25Å; W466-L667 HydrophobicContact CG-CD2 3.7Å; W466-F678 HydrophobicContact CD2-CE1 4.37Å; W466-F678 HydrophobicContact CD2-CZ 4.11Å; W466-F678 AromaticContact CE2-CE1 3.55Å; W466-F678 AromaticContact CE2-CZ 3.63Å; W466-F678 HydrophobicContact CG-CZ 4.47Å; W466-F678 AromaticContact CH2-CE1 3.95Å; W466-F678 HydrophobicContact CH2-CE1 3.95Å; W466-F678 HydrophobicContact CZ2-CD1 4.26Å; W466-F678 AromaticContact CZ2-CE1 3.31Å; W466-F678 HydrophobicContact CZ2-CE1 3.31Å; W466-F678 AromaticContact CZ2-CZ 3.89Å; W466-F678 HydrophobicContact CZ2-CZ 3.89Å; W466-F678 AromaticContact NE1-CE1 3.89Å; W466-F678 AromaticContact NE1-CZ 3.75Å
467W92.9Very high92.7Very high142 Ų14242.4 Ų42.454%0.53820%0.196SC..Hα-helixtrans-61.9-39.3178-167.5-116000112.4A463 R465 I469 F470 L471A463-W467 PolarHBondContact O-N 3.41Å; R465-W467 PolarHBondContact O-N 2.66Å; W467-I469 VanDerWaalsContact C-N 3.33Å; W467-I469 PolarHBondContact O-N 3.26Å; W467-F470 HydrophobicContact CE3-CD1 4.41Å; W467-F470 HydrophobicContact CH2-CD1 4.46Å; W467-F470 HydrophobicContact CZ3-CD1 4.19Å; W467-F470 WeakPolarHBondContact O-CB 3.34Å; W467-F470 PolarHBondContact O-N 3.28Å; W467-L471 WeakPolarHBondContact O-CG 3.24Å; W467-L471 PolarHBondContact O-N 3.32Å
468K91.9Very high92.9Very high44 Ų4447.4 Ų47.419%0.19121%0.213CC..Hα-helixtrans-63.6-39.1175.3-174.7-170.9179.7-155.30111.9K464 R465 W466 T472 K600K464-K468 WeakPolarHBondContact O-CB 3.13Å; K464-K468 PolarHBondContact O-N 3.26Å; K464-K468 VanDerWaalsContact O-N 3.16Å; R465-K468 WeakPolarHBondContact O-CB 3.42Å; R465-K468 PolarHBondContact O-N 3.33Å; R465-K468 VanDerWaalsContact O-N 3.16Å; W466-K468 VanDerWaalsContact C-N 3.3Å; W466-K468 PolarHBondContact O-N 2.91Å; K468-T472 WeakPolarHBondContact O-CB 3.4Å; K468-T472 PolarHBondContact O-N 2.87Å; K468-T472 PolarHBondContact O-OG1 2.94Å; K468-K600 VanDerWaalsContact CE-CE 3.45Å
469I93.7Very high93.1Very high5 Ų547.5 Ų47.53%0.02621%0.214CC..Hα-helixtrans-62.5-49175.8-65.8167.2000109.3R465 W466 W467 L471 T472 I473 L601 L604 P670 F671 F678R465-I469 HydrophobicContact CG-CD1 4.18Å; R465-I469 WeakPolarHBondContact O-CG1 3.36Å; R465-I469 PolarHBondContact O-N 3.1Å; W466-I469 WeakPolarHBondContact O-CB 3.46Å; W466-I469 PolarHBondContact O-N 3.02Å; W466-I469 VanDerWaalsContact O-N 3.11Å; W467-I469 VanDerWaalsContact C-N 3.33Å; W467-I469 PolarHBondContact O-N 3.26Å; I469-L471 PolarHBondContact O-N 2.98Å; I469-T472 WeakPolarHBondContact O-CB 3.34Å; I469-T472 PolarHBondContact O-N 3.42Å; I469-I473 PolarHBondContact O-N 3.26Å; I469-L601 HydrophobicContact CG2-CD1 3.99Å; I469-L604 HydrophobicContact CG1-CB 4.39Å; I469-L604 HydrophobicContact CG1-CD1 4.03Å; I469-P670 HydrophobicContact CB-CG 4.36Å; I469-P670 HydrophobicContact CD1-CG 3.92Å; I469-P670 HydrophobicContact CG2-CG 3.92Å; I469-F671 HydrophobicContact CG2-CE1 3.92Å; I469-F671 HydrophobicContact CG2-CE2 3.7Å; I469-F671 HydrophobicContact CG2-CZ 3.2Å; I469-F678 HydrophobicContact CB-CE2 4.32Å; I469-F678 HydrophobicContact CG2-CE2 3.8Å
470F90.6Very high93.2Very high69 Ų6946.4 Ų46.430%0.30321%0.208SC..Hα-helixtrans-53.5-50.9177.3-178.7-108.8000112.5W466 W467 T472 I473 F678W466-F470 PolarHBondContact O-N 3.36Å; W467-F470 HydrophobicContact CE3-CD1 4.41Å; W467-F470 HydrophobicContact CH2-CD1 4.46Å; W467-F470 HydrophobicContact CZ3-CD1 4.19Å; W467-F470 WeakPolarHBondContact O-CB 3.34Å; W467-F470 PolarHBondContact O-N 3.28Å; F470-T472 PolarHBondContact O-N 2.92Å; F470-T472 VanDerWaalsContact O-N 3.15Å; F470-I473 HydrophobicContact CD2-CD1 4.26Å; F470-I473 WeakPolarHBondContact O-CB 3.45Å; F470-I473 PolarHBondContact O-N 2.72Å; F470-I473 VanDerWaalsContact O-N 3.13Å; F470-F678 HydrophobicContact CB-CE1 3.89Å; F470-F678 HydrophobicContact CB-CE2 4.17Å; F470-F678 HydrophobicContact CB-CZ 3.5Å; F470-F678 VanDerWaalsContact CB-CZ 3.5Å; F470-F678 AromaticContact CD2-CD1 3.88Å; F470-F678 HydrophobicContact CD2-CD1 3.88Å; F470-F678 AromaticContact CD2-CE1 3.54Å; F470-F678 HydrophobicContact CD2-CE1 3.54Å; F470-F678 AromaticContact CD2-CZ 3.96Å; F470-F678 HydrophobicContact CD2-CZ 3.96Å; F470-F678 HydrophobicContact CE2-CE1 4.5Å; F470-F678 HydrophobicContact CG-CE1 4.1Å; F470-F678 HydrophobicContact CG-CZ 4.19Å
471L92.3Very high93.3Very high109 Ų10946.6 Ų46.657%0.57121%0.214SC*.Hα-helixtrans-67.6-12.4179.7-66.9177.4000114W467 I469W467-L471 WeakPolarHBondContact O-CG 3.24Å; W467-L471 PolarHBondContact O-N 3.32Å; I469-L471 PolarHBondContact O-N 2.98Å
472T93.7Very high93.5Very high2 Ų247.1 Ų47.11%0.01222%0.217CC..Hα-helixtrans-93.4-13.4177.5-55.60000111.9K468 I469 F470 S474 N597 K600 L601K468-T472 WeakPolarHBondContact O-CB 3.4Å; K468-T472 PolarHBondContact O-N 2.87Å; K468-T472 PolarHBondContact O-OG1 2.94Å; I469-T472 WeakPolarHBondContact O-CB 3.34Å; I469-T472 PolarHBondContact O-N 3.42Å; F470-T472 PolarHBondContact O-N 2.92Å; F470-T472 VanDerWaalsContact O-N 3.15Å; T472-S474 PolarHBondContact O-N 3.18Å; T472-N597 HydrophobicContact CG2-CB 4.39Å; T472-N597 WeakPolarHBondContact CG2-O 3.5Å; T472-K600 HydrophobicContact CG2-CB 3.88Å; T472-K600 HydrophobicContact CG2-CD 3.92Å; T472-K600 HydrophobicContact CG2-CG 3.97Å; T472-L601 HydrophobicContact CG2-CB 4.23Å; T472-L601 HydrophobicContact CG2-CD1 4.12Å
473I93.4Very high93.7Very high5 Ų547.1 Ų47.13%0.02622%0.217CC..SBendtrans-58131.2174-64.2173.8000109.4I469 F470 F678 L680 I683I469-I473 PolarHBondContact O-N 3.26Å; F470-I473 HydrophobicContact CD2-CD1 4.26Å; F470-I473 WeakPolarHBondContact O-CB 3.45Å; F470-I473 PolarHBondContact O-N 2.72Å; F470-I473 VanDerWaalsContact O-N 3.13Å; I473-F678 HydrophobicContact CD1-CB 4.29Å; I473-F678 HydrophobicContact CD1-CD2 3.63Å; I473-F678 HydrophobicContact CD1-CE2 4.13Å; I473-F678 HydrophobicContact CD1-CG 3.98Å; I473-L680 HydrophobicContact CD1-CD2 4.06Å; I473-I683 HydrophobicContact CG2-CD1 4.28Å; I473-I683 HydrophobicContact CG2-CG2 4.32Å
474S89.4Confident93.7Very high4 Ų446.1 Ų46.13%0.02821%0.207CC..  trans-82.2126.6-174.2-67.90000111.9T472 I598 N687T472-S474 PolarHBondContact O-N 3.18Å; S474-I598 VanDerWaalsContact OG-CG2 3.24Å; S474-I598 WeakPolarHBondContact OG-CG2 3.14Å; S474-N687 PolarHBondContact O-ND2 3.43Å
475W92.1Very high93.6Very high101 Ų10146.5 Ų46.538%0.38322%0.215SC..  trans-113.4108.6176.1-63.393.4000108.9D477 I683W475-D477 VanDerWaalsContact C-N 3.26Å; W475-D477 PolarHBondContact O-N 3.28Å; W475-I683 HydrophobicContact CH2-CD1 3.97Å; W475-I683 HydrophobicContact CH2-CG1 3.84Å; W475-I683 HydrophobicContact CH2-CG2 4.24Å; W475-I683 HydrophobicContact CZ2-CD1 4.01Å; W475-I683 HydrophobicContact CZ2-CG1 4.38Å; W475-I683 HydrophobicContact CZ3-CG1 4.45Å; W475-I683 HydrophobicContact CZ3-CG2 4.23Å
476P95Very high93.8Very high4 Ų448.3 Ų48.33%0.02622%0.222CC..  trans-83.35.8-170.734.2-36.2000114R478 A479 A480 I505 N687 C691P476-R478 PolarHBondContact O-N 3.35Å; P476-A479 CarbonylContact O-C 3.31Å; P476-A479 WeakPolarHBondContact O-CA 3.38Å; P476-A479 WeakPolarHBondContact O-CB 3.39Å; P476-A479 PolarHBondContact O-N 2.83Å; P476-A479 VanDerWaalsContact O-N 3.13Å; P476-A480 WeakPolarHBondContact O-CB 3.1Å; P476-A480 PolarHBondContact O-N 3.48Å; P476-I505 HydrophobicContact CB-CG2 3.88Å; P476-N687 WeakPolarHBondContact CD-ND2 3.28Å; P476-N687 HydrophobicContact CG-CB 3.7Å; P476-C691 VanDerWaalsContact CG-SG 3.51Å
477D93.3Very high93.9Very high42 Ų4245.7 Ų45.723%0.22521%0.212CC..Hα-helixtrans-51.9-54-177.8-60.4-117.6000112.9W475 A479 A480 S481 R686 L690W475-D477 VanDerWaalsContact C-N 3.26Å; W475-D477 PolarHBondContact O-N 3.28Å; D477-A479 PolarHBondContact O-N 2.92Å; D477-A480 PolarHBondContact O-N 3.2Å; D477-A480 VanDerWaalsContact O-N 3.11Å; D477-S481 PolarHBondContact O-N 2.92Å; D477-S481 PolarHBondContact O-OG 3.47Å; D477-R686 IonicContact OD1-CZ 2.72Å; D477-R686 IonicContact OD1-NH1 2.83Å; D477-R686 PolarHBondContact OD1-NH1 3.12Å; D477-R686 IonicContact OD1-NH2 3.69Å; D477-R686 PolarHBondContact OD1-NH2 3.45Å; D477-R686 IonicContact OD2-CZ 3.27Å; D477-R686 IonicContact OD2-NH1 2.66Å; D477-R686 PolarHBondContact OD2-NH1 3.36Å; D477-R686 IonicContact OD2-NH2 3.63Å; D477-L690 HydrophobicContact CB-CD2 4.16Å; D477-L690 WeakPolarHBondContact OD1-CD1 3.44Å; D477-L690 WeakPolarHBondContact OD1-CD2 3.39Å
478R94.9Very high93.7Very high145 Ų14543.5 Ų43.555%0.54721%0.206SC..Hα-helixtrans-63-38.1-178.3-172.2165.861.6889110.3P476 I482 E590P476-R478 PolarHBondContact O-N 3.35Å; R478-I482 HydrophobicContact CG-CD1 3.97Å; R478-I482 WeakPolarHBondContact O-CB 3.22Å; R478-I482 WeakPolarHBondContact O-CD1 3.42Å; R478-I482 WeakPolarHBondContact O-CG1 3.46Å; R478-I482 PolarHBondContact O-N 3.29Å; R478-E590 IonicContact CZ-OE1 3Å; R478-E590 IonicContact CZ-OE2 2.89Å; R478-E590 IonicContact NE-OE1 3.34Å; R478-E590 PolarHBondContact NE-OE1 3.08Å; R478-E590 IonicContact NE-OE2 3.22Å; R478-E590 IonicContact NH1-OE1 2.66Å; R478-E590 IonicContact NH1-OE2 2.7Å; R478-E590 PolarHBondContact NH1-OE2 2.72Å; R478-E590 IonicContact NH2-OE1 3.58Å; R478-E590 PolarHBondContact NH2-OE1 3.34Å; R478-E590 IonicContact NH2-OE2 3.97Å; R478-E590 PolarHBondContact NH2-OE2 3.46Å
479A96.2Very high93.5Very high2 Ų242.3 Ų42.32%0.01721%0.206CC..Hα-helixtrans-63.6-45.1172.500000112.7P476 D477 I482 V483 I505 E590 I594P476-A479 CarbonylContact O-C 3.31Å; P476-A479 WeakPolarHBondContact O-CA 3.38Å; P476-A479 WeakPolarHBondContact O-CB 3.39Å; P476-A479 PolarHBondContact O-N 2.83Å; P476-A479 VanDerWaalsContact O-N 3.13Å; D477-A479 PolarHBondContact O-N 2.92Å; A479-I482 PolarHBondContact O-N 3.34Å; A479-V483 VanDerWaalsContact O-CB 3.29Å; A479-V483 WeakPolarHBondContact O-CB 3.5Å; A479-V483 WeakPolarHBondContact O-CG2 3.33Å; A479-V483 PolarHBondContact O-N 2.69Å; A479-I505 HydrophobicContact CB-CD1 3.88Å; A479-E590 VanDerWaalsContact CA-CG 3.49Å; A479-E590 HydrophobicContact CB-CG 3.47Å; A479-E590 VanDerWaalsContact CB-CG 3.47Å; A479-I594 HydrophobicContact CB-CD1 3.76Å
480A95.9Very high93.1Very high0 Ų048.7 Ų48.70%025%0.245CC..Hα-helixtrans-63.6-43.5178.200000111.7P476 D477 V483 S484 V502 C691 V694 V695P476-A480 WeakPolarHBondContact O-CB 3.1Å; P476-A480 PolarHBondContact O-N 3.48Å; D477-A480 PolarHBondContact O-N 3.2Å; D477-A480 VanDerWaalsContact O-N 3.11Å; A480-V483 PolarHBondContact O-N 3.45Å; A480-S484 VanDerWaalsContact O-CB 3.26Å; A480-S484 WeakPolarHBondContact O-CB 3.41Å; A480-S484 PolarHBondContact O-N 3.15Å; A480-V502 HydrophobicContact CB-CG1 3.99Å; A480-C691 HydrophobicContact CB-CB 4.31Å; A480-V694 HydrophobicContact CB-CB 4.17Å; A480-V694 HydrophobicContact CB-CG1 4.02Å; A480-V695 HydrophobicContact CB-CG1 4.28Å
481S94.2Very high93.2Very high66 Ų6648.6 Ų48.646%0.46225%0.248SC..Hα-helixtrans-62.7-45175.5-62.30000111.8D477 S484 L485D477-S481 PolarHBondContact O-N 2.92Å; D477-S481 PolarHBondContact O-OG 3.47Å; S481-S484 PolarHBondContact O-N 3.28Å; S481-L485 VanDerWaalsContact O-CB 3.28Å; S481-L485 WeakPolarHBondContact O-CB 3.23Å; S481-L485 PolarHBondContact O-N 3.35Å
482I96.7Very high93.1Very high24 Ų2447.6 Ų47.612%0.12324%0.241CC..Hα-helixtrans-64.9-43.2177.9-73.3169.3000111.2R478 A479 L485 Y486 T586 V587 E590R478-I482 HydrophobicContact CG-CD1 3.97Å; R478-I482 WeakPolarHBondContact O-CB 3.22Å; R478-I482 WeakPolarHBondContact O-CD1 3.42Å; R478-I482 WeakPolarHBondContact O-CG1 3.46Å; R478-I482 PolarHBondContact O-N 3.29Å; A479-I482 PolarHBondContact O-N 3.34Å; I482-L485 PolarHBondContact O-N 3.17Å; I482-Y486 HydrophobicContact CG2-CD2 3.65Å; I482-Y486 HydrophobicContact CG2-CE2 3.96Å; I482-Y486 WeakPolarHBondContact O-CB 3.44Å; I482-Y486 PolarHBondContact O-N 2.84Å; I482-T586 HydrophobicContact CD1-CG2 4.15Å; I482-T586 HydrophobicContact CG2-CG2 4.26Å; I482-V587 HydrophobicContact CG2-CB 4.38Å; I482-V587 HydrophobicContact CG2-CG2 3.85Å; I482-E590 HydrophobicContact CD1-CB 4.49Å; I482-E590 HydrophobicContact CD1-CG 4.31Å
483V97.3Very high93.1Very high2 Ų250.7 Ų50.71%0.01225%0.252CS..Hα-helixtrans-63.7-43.2175.8165.90000110.8A479 A480 L485 I487 R498 L501 V502 V587 V695A479-V483 VanDerWaalsContact O-CB 3.29Å; A479-V483 WeakPolarHBondContact O-CB 3.5Å; A479-V483 WeakPolarHBondContact O-CG2 3.33Å; A479-V483 PolarHBondContact O-N 2.69Å; A480-V483 PolarHBondContact O-N 3.45Å; V483-L485 VanDerWaalsContact C-N 3.31Å; V483-L485 PolarHBondContact O-N 3.13Å; V483-I487 HydrophobicContact CG1-CG1 4.03Å; V483-I487 VanDerWaalsContact O-CB 3.29Å; V483-I487 WeakPolarHBondContact O-CB 2.98Å; V483-I487 WeakPolarHBondContact O-CG1 3.26Å; V483-I487 PolarHBondContact O-N 3.12Å; V483-R498 HydrophobicContact CG1-CB 3.91Å; V483-R498 HydrophobicContact CG1-CG 3.9Å; V483-L501 HydrophobicContact CG1-CB 4.22Å; V483-L501 HydrophobicContact CG1-CD1 3.96Å; V483-L501 HydrophobicContact CG2-CB 4.34Å; V483-L501 HydrophobicContact CG2-CD1 4.16Å; V483-V502 HydrophobicContact CG1-CG1 4.47Å; V483-V587 HydrophobicContact CG2-CG1 4.11Å; V483-V695 HydrophobicContact CB-CG1 4.5Å; V483-V695 HydrophobicContact CG1-CG1 4.11Å
484S94.3Very high93.1Very high13 Ų1350.4 Ų50.49%0.09125%0.251CS..Hα-helixtrans-62.8-38.8176-167.40000111.9A480 S481 V694 H699A480-S484 VanDerWaalsContact O-CB 3.26Å; A480-S484 WeakPolarHBondContact O-CB 3.41Å; A480-S484 PolarHBondContact O-N 3.15Å; S481-S484 PolarHBondContact O-N 3.28Å; S484-V694 WeakPolarHBondContact CB-O 3.23Å; S484-V694 PolarHBondContact OG-O 2.85Å; S484-H699 PolarHBondContact O-CE1 2.78Å; S484-H699 PolarHBondContact O-ND1 3.14Å; S484-H699 PolarHBondContact OG-ND1 3.2Å; S484-H699 VanDerWaalsContact OG-ND1 3.14Å
485L92.3Very high93.3Very high122 Ų12253 Ų5364%0.63926%0.26SS*.Hα-helixtrans-75-42.8-179-176.262.6000113.2S481 I482 V483S481-L485 VanDerWaalsContact O-CB 3.28Å; S481-L485 WeakPolarHBondContact O-CB 3.23Å; S481-L485 PolarHBondContact O-N 3.35Å; I482-L485 PolarHBondContact O-N 3.17Å; V483-L485 VanDerWaalsContact C-N 3.31Å; V483-L485 PolarHBondContact O-N 3.13Å
486Y95.7Very high93.4Very high59 Ų5949.1 Ų49.123%0.23125%0.246CC..Hα-helixtrans-102-15.2-167.8-64-24.7000115.4I482 Q583 T586 V587I482-Y486 HydrophobicContact CG2-CD2 3.65Å; I482-Y486 HydrophobicContact CG2-CE2 3.96Å; I482-Y486 WeakPolarHBondContact O-CB 3.44Å; I482-Y486 PolarHBondContact O-N 2.84Å; Y486-Q583 HydrophobicContact CD1-CB 4.2Å; Y486-Q583 HydrophobicContact CD1-CG 3.64Å; Y486-Q583 HydrophobicContact CD2-CB 4.03Å; Y486-Q583 HydrophobicContact CD2-CG 4.24Å; Y486-Q583 HydrophobicContact CE1-CG 3.87Å; Y486-Q583 HydrophobicContact CE2-CG 4.45Å; Y486-Q583 HydrophobicContact CG-CB 3.87Å; Y486-Q583 HydrophobicContact CG-CG 3.86Å; Y486-T586 HydrophobicContact CE2-CG2 3.76Å; Y486-V587 HydrophobicContact CD2-CG2 3.98Å
487I95.5Very high93.5Very high0 Ų049 Ų490%025%0.245CC..SBendtrans-94.5102.4172.5-52.8-55.4000109.2V483 I497 R498 L501 A572 I578V483-I487 HydrophobicContact CG1-CG1 4.03Å; V483-I487 VanDerWaalsContact O-CB 3.29Å; V483-I487 WeakPolarHBondContact O-CB 2.98Å; V483-I487 WeakPolarHBondContact O-CG1 3.26Å; V483-I487 PolarHBondContact O-N 3.12Å; I487-I497 HydrophobicContact CG2-CB 4.16Å; I487-I497 HydrophobicContact CG2-CG2 3.69Å; I487-R498 HydrophobicContact CB-CG 3.65Å; I487-R498 HydrophobicContact CG1-CG 4.37Å; I487-R498 HydrophobicContact CG2-CG 3.7Å; I487-R498 PolarHBondContact O-NH1 2.87Å; I487-L501 HydrophobicContact CD1-CD1 4.21Å; I487-L501 HydrophobicContact CG1-CD1 3.95Å; I487-A572 HydrophobicContact CD1-CB 4.39Å; I487-I578 HydrophobicContact CD1-CD1 3.51Å; I487-I578 HydrophobicContact CD1-CG1 3.61Å
488K90.2Very high93.7Very high95 Ų9547.2 Ų47.241%0.41324%0.236SC..  trans-73.6156-178.6-69.4-170.7164.8-166.30113.8R577 E579K488-R577 WeakPolarHBondContact CB-O 3.4Å; K488-R577 PolarHBondContact N-O 3.3Å; K488-R577 PolarHBondContact O-NH1 2.81Å; K488-E579 HydrophobicContact CD-CG 3.97Å; K488-E579 VanDerWaalsContact CE-CG 3.45Å; K488-E579 WeakPolarHBondContact CE-OE1 3.43Å; K488-E579 IonicContact NZ-OE1 2.52Å; K488-E579 PolarHBondContact NZ-OE1 2.74Å; K488-E579 IonicContact NZ-OE2 3.91Å
489G86.4Confident93.7Very high19 Ų1940.4 Ų40.420%0.19621%0.21CC..  trans122.4115.7172.800000112D491 R498G489-D491 WeakPolarHBondContact CA-OD1 3.3Å; G489-R498 PolarHBondContact O-NH1 3.01Å; G489-R498 PolarHBondContact O-NH2 3.05Å
490T86.6Confident93.8Very high139 Ų13940.3 Ų40.385%0.85321%0.209SC*.SBendtrans-82.9-6.2166.851.60000111.7
491D91.8Very high93.9Very high67 Ų6740.3 Ų40.336%0.35821%0.209SC..SBendtrans-73.6165.317566.4-38.7000112.4G489 R493 G494 R495 R577G489-D491 WeakPolarHBondContact CA-OD1 3.3Å; D491-R493 PolarHBondContact O-N 3.17Å; D491-R493 WeakPolarHBondContact OD2-CB 3.3Å; D491-G494 PolarHBondContact O-N 2.91Å; D491-G494 VanDerWaalsContact O-N 3.16Å; D491-G494 PolarHBondContact OD1-N 2.86Å; D491-R495 PolarHBondContact O-N 3.19Å; D491-R495 VanDerWaalsContact O-N 3.07Å; D491-R577 IonicContact OD1-CZ 2.79Å; D491-R577 IonicContact OD1-NH1 2.86Å; D491-R577 PolarHBondContact OD1-NH1 3.39Å; D491-R577 IonicContact OD1-NH2 3.9Å; D491-R577 IonicContact OD2-CZ 3.31Å; D491-R577 IonicContact OD2-NH1 3.74Å; D491-R577 PolarHBondContact OD2-NH1 3.14Å; D491-R577 IonicContact OD2-NH2 3Å; D491-R577 PolarHBondContact OD2-NH2 3.2Å
492E90.5Very high94Very high88 Ų8837.2 Ų37.241%0.41119%0.188SC..Hα-helixtrans-57.4-37.9-178.1-163.6-179.5158.500112.1R334 W338 R495 M496R334-E492 IonicContact CZ-OE1 3.64Å; R334-E492 IonicContact CZ-OE2 3.73Å; R334-E492 IonicContact NE-OE1 3.75Å; R334-E492 PolarHBondContact NE-OE1 2.97Å; R334-E492 IonicContact NH2-OE1 2.7Å; R334-E492 PolarHBondContact NH2-OE1 3.48Å; R334-E492 IonicContact NH2-OE2 2.82Å; R334-E492 PolarHBondContact NH2-OE2 2.96Å; W338-E492 HydrophobicContact CH2-CG 4.49Å; W338-E492 HydrophobicContact CZ2-CG 3.72Å; E492-R495 PolarHBondContact O-N 3.41Å; E492-M496 VanDerWaalsContact O-CB 3.28Å; E492-M496 WeakPolarHBondContact O-CB 3.47Å; E492-M496 PolarHBondContact O-N 3.41Å
493R93.8Very high94.1Very high67 Ų6736.2 Ų36.225%0.25318%0.182SC..Hα-helixtrans-66.9-43.5179.1175.859.7171.3-160-3112.1L332 D491 M496 I497 E575L332-R493 VanDerWaalsContact CD1-CZ 3.47Å; D491-R493 PolarHBondContact O-N 3.17Å; D491-R493 WeakPolarHBondContact OD2-CB 3.3Å; R493-M496 PolarHBondContact O-N 2.67Å; R493-I497 HydrophobicContact CG-CD1 4.23Å; R493-I497 WeakPolarHBondContact O-CG1 3.35Å; R493-I497 PolarHBondContact O-N 3.24Å; R493-E575 IonicContact CZ-OE1 2.82Å; R493-E575 IonicContact CZ-OE2 3.49Å; R493-E575 IonicContact NE-OE1 2.75Å; R493-E575 IonicContact NE-OE2 3.16Å; R493-E575 PolarHBondContact NE-OE2 3.01Å; R493-E575 VanDerWaalsContact NE-OE2 3.09Å; R493-E575 IonicContact NH2-OE1 3.51Å; R493-E575 PolarHBondContact NH2-OE1 3.39Å; R493-E575 IonicContact NH2-OE2 3.68Å
494G93.4Very high94.1Very high0 Ų036.2 Ų36.20%018%0.182CC..Hα-helixtrans-59.8-47.5174.800000111.6D491 M496 I497 R498D491-G494 PolarHBondContact O-N 2.91Å; D491-G494 VanDerWaalsContact O-N 3.16Å; D491-G494 PolarHBondContact OD1-N 2.86Å; G494-M496 VanDerWaalsContact C-N 3.33Å; G494-M496 PolarHBondContact O-N 2.77Å; G494-I497 PolarHBondContact O-N 3.18Å; G494-R498 WeakPolarHBondContact O-CG 3.2Å; G494-R498 PolarHBondContact O-N 3.49Å; G494-R498 VanDerWaalsContact O-N 3.13Å; G494-R498 PolarHBondContact O-NH1 3.38Å
495R93.7Very high94.3Very high57 Ų5735.6 Ų35.622%0.21518%0.178CC..Hα-helixtrans-56.9-44.7174.2-174.1-177.8-174.6-139.4-1.8111.9W338 D491 E492 R498 R499 D696W338-R495 HydrophobicContact CH2-CB 4.25Å; W338-R495 HydrophobicContact CH2-CG 3.94Å; W338-R495 HydrophobicContact CZ2-CG 4.2Å; W338-R495 PolarHBondContact O-NH1 3.2Å; W338-R495 PolarHBondContact O-NH2 3.41Å; D491-R495 PolarHBondContact O-N 3.19Å; D491-R495 VanDerWaalsContact O-N 3.07Å; E492-R495 PolarHBondContact O-N 3.41Å; R495-R498 PolarHBondContact O-N 2.72Å; R495-R499 HydrophobicContact CG-CG 4.43Å; R495-R499 WeakPolarHBondContact O-CB 3.32Å; R495-R499 WeakPolarHBondContact O-CG 3.47Å; R495-R499 PolarHBondContact O-N 2.72Å; R495-D696 WeakPolarHBondContact CD-OD1 3.47Å; R495-D696 IonicContact CZ-OD1 3.97Å; R495-D696 IonicContact CZ-OD2 2.71Å; R495-D696 VanDerWaalsContact CZ-OD2 3.23Å; R495-D696 IonicContact NE-OD1 2.68Å; R495-D696 PolarHBondContact NE-OD1 3.22Å; R495-D696 IonicContact NE-OD2 3.53Å; R495-D696 PolarHBondContact NE-OD2 3.49Å; R495-D696 IonicContact NH2-OD1 3.49Å; R495-D696 IonicContact NH2-OD2 2.91Å; R495-D696 PolarHBondContact NH2-OD2 3.02Å
496M94.8Very high94.5Very high20 Ų2030.2 Ų30.210%0.09915%0.149CC..Hα-helixtrans-63.4-44.2-178.6-171.8178.8-69.200112.4L332 R334 W338 E492 R493 G494 T500L332-M496 HydrophobicContact CB-CG 4.37Å; L332-M496 HydrophobicContact CB-SD 3.71Å; R334-M496 HydrophobicContact CG-CE 4.37Å; W338-M496 HydrophobicContact CH2-CB 3.78Å; W338-M496 HydrophobicContact CH2-CE 4.46Å; W338-M496 HydrophobicContact CH2-CG 4.35Å; W338-M496 HydrophobicContact CZ3-CB 4.28Å; W338-M496 HydrophobicContact CZ3-CG 4.46Å; E492-M496 VanDerWaalsContact O-CB 3.28Å; E492-M496 WeakPolarHBondContact O-CB 3.47Å; E492-M496 PolarHBondContact O-N 3.41Å; R493-M496 PolarHBondContact O-N 2.67Å; G494-M496 VanDerWaalsContact C-N 3.33Å; G494-M496 PolarHBondContact O-N 2.77Å; M496-T500 VanDerWaalsContact O-CB 3.24Å; M496-T500 WeakPolarHBondContact O-CB 3.35Å; M496-T500 PolarHBondContact O-N 3.22Å; M496-T500 PolarHBondContact O-OG1 2.93Å
497I97.1Very high94.7Very high1 Ų127.4 Ų27.41%0.00514%0.138CC..Hα-helixtrans-61.5-50.3177.2-67.2167.8000109.7I487 R493 G494 R499 T500 L501 L568 A572I487-I497 HydrophobicContact CG2-CB 4.16Å; I487-I497 HydrophobicContact CG2-CG2 3.69Å; R493-I497 HydrophobicContact CG-CD1 4.23Å; R493-I497 WeakPolarHBondContact O-CG1 3.35Å; R493-I497 PolarHBondContact O-N 3.24Å; G494-I497 PolarHBondContact O-N 3.18Å; I497-R499 PolarHBondContact O-N 3.21Å; I497-T500 PolarHBondContact O-N 2.85Å; I497-L501 HydrophobicContact CG2-CD1 3.97Å; I497-L501 HydrophobicContact CG2-CG 4.41Å; I497-L501 VanDerWaalsContact O-CG 3.31Å; I497-L501 WeakPolarHBondContact O-CG 3.16Å; I497-L501 PolarHBondContact O-N 3.37Å; I497-L568 HydrophobicContact CG1-CD1 4.32Å; I497-L568 HydrophobicContact CG2-CD1 4.37Å; I497-L568 HydrophobicContact CG2-CD2 4.45Å; I497-L568 HydrophobicContact CG2-CG 4.2Å; I497-A572 HydrophobicContact CD1-CB 4.3Å; I497-A572 HydrophobicContact CG2-CB 4.07Å
498R96.6Very high94.7Very high6 Ų627.4 Ų27.42%0.02314%0.138CC..Hα-helixtrans-60.4-48.2-178.5-70-168-66.2-81.1-1.2112.9V483 I487 G489 G494 R495 T500 L501 V502 V695 H699V483-R498 HydrophobicContact CG1-CB 3.91Å; V483-R498 HydrophobicContact CG1-CG 3.9Å; I487-R498 HydrophobicContact CB-CG 3.65Å; I487-R498 HydrophobicContact CG1-CG 4.37Å; I487-R498 HydrophobicContact CG2-CG 3.7Å; I487-R498 PolarHBondContact O-NH1 2.87Å; G489-R498 PolarHBondContact O-NH1 3.01Å; G489-R498 PolarHBondContact O-NH2 3.05Å; G494-R498 WeakPolarHBondContact O-CG 3.2Å; G494-R498 PolarHBondContact O-N 3.49Å; G494-R498 VanDerWaalsContact O-N 3.13Å; G494-R498 PolarHBondContact O-NH1 3.38Å; R495-R498 PolarHBondContact O-N 2.72Å; R498-T500 VanDerWaalsContact C-N 3.34Å; R498-T500 PolarHBondContact O-N 2.93Å; R498-L501 PolarHBondContact O-N 3.45Å; R498-V502 PolarHBondContact O-N 3.25Å; R498-V695 HydrophobicContact CB-CB 3.9Å; R498-V695 HydrophobicContact CB-CG1 4.41Å; R498-V695 HydrophobicContact CB-CG2 4.29Å; R498-V695 PolarHBondContact NE-O 3.2Å; R498-H699 VanDerWaalsContact CZ-CD2 3.47Å; R498-H699 PolarHBondContact NH1-NE2 3.37Å; R498-H699 PolarHBondContact NH2-CD2 3.46Å; R498-H699 PolarHBondContact NH2-NE2 3.48Å
499R95.2Very high95.1Very high1 Ų123.3 Ų23.30%0.00412%0.122CC..Hα-helixtrans-62.3-41.3178.5-71.8178.664.293.43.9111.8D335 H337 R495 I497 V502 R503 Y692 V695 D696D335-R499 IonicContact OD1-CZ 3.77Å; D335-R499 IonicContact OD1-NH2 3.15Å; D335-R499 PolarHBondContact OD1-NH2 3.39Å; D335-R499 IonicContact OD2-CZ 2.77Å; D335-R499 VanDerWaalsContact OD2-CZ 3.25Å; D335-R499 IonicContact OD2-NE 2.86Å; D335-R499 PolarHBondContact OD2-NE 3.03Å; D335-R499 IonicContact OD2-NH2 3.41Å; D335-R499 PolarHBondContact OD2-NH2 3.38Å; H337-R499 VanDerWaalsContact C-NH2 3.29Å; H337-R499 PolarHBondContact O-NH2 3.3Å; R495-R499 HydrophobicContact CG-CG 4.43Å; R495-R499 WeakPolarHBondContact O-CB 3.32Å; R495-R499 WeakPolarHBondContact O-CG 3.47Å; R495-R499 PolarHBondContact O-N 2.72Å; I497-R499 PolarHBondContact O-N 3.21Å; R499-V502 VanDerWaalsContact O-CG2 3.3Å; R499-V502 WeakPolarHBondContact O-CG2 3.42Å; R499-R503 VanDerWaalsContact O-CB 3.23Å; R499-R503 WeakPolarHBondContact O-CB 3.24Å; R499-R503 PolarHBondContact O-N 3.47Å; R499-Y692 HydrophobicContact CB-CD1 4.47Å; R499-Y692 HydrophobicContact CB-CE1 4.15Å; R499-Y692 HydrophobicContact CG-CD1 4.24Å; R499-Y692 HydrophobicContact CG-CE1 4.38Å; R499-V695 HydrophobicContact CG-CG2 3.99Å; R499-D696 IonicContact CZ-OD2 3.7Å; R499-D696 IonicContact NH1-OD2 3.51Å; R499-D696 PolarHBondContact NH1-OD2 3.25Å
500T97.4Very high95.5Very high1 Ų122.5 Ų22.51%0.00611%0.113CC..Hα-helixtrans-65.6-41.8178.2-57.90000111.9L332 M496 I497 R498 R503 Y504 L568L332-T500 HydrophobicContact CD2-CG2 3.79Å; M496-T500 VanDerWaalsContact O-CB 3.24Å; M496-T500 WeakPolarHBondContact O-CB 3.35Å; M496-T500 PolarHBondContact O-N 3.22Å; M496-T500 PolarHBondContact O-OG1 2.93Å; I497-T500 PolarHBondContact O-N 2.85Å; R498-T500 VanDerWaalsContact C-N 3.34Å; R498-T500 PolarHBondContact O-N 2.93Å; T500-R503 PolarHBondContact O-N 3.04Å; T500-Y504 HydrophobicContact CG2-CD1 4.32Å; T500-Y504 HydrophobicContact CG2-CD2 3.91Å; T500-Y504 HydrophobicContact CG2-CE1 3.89Å; T500-Y504 HydrophobicContact CG2-CE2 3.44Å; T500-Y504 VanDerWaalsContact CG2-CE2 3.44Å; T500-Y504 HydrophobicContact CG2-CG 4.33Å; T500-Y504 VanDerWaalsContact CG2-CZ 3.41Å; T500-Y504 PolarHBondContact O-N 3.48Å; T500-L568 HydrophobicContact CG2-CD2 3.67Å
501L98.2Very high95.9Very high0 Ų016.1 Ų16.10%07%0.073CC..Hα-helixtrans-59.2-50.8178.2-74.5172.6000112.2V483 I487 I497 R498 R503 Y504 I505 A565 L568 V569V483-L501 HydrophobicContact CG1-CB 4.22Å; V483-L501 HydrophobicContact CG1-CD1 3.96Å; V483-L501 HydrophobicContact CG2-CB 4.34Å; V483-L501 HydrophobicContact CG2-CD1 4.16Å; I487-L501 HydrophobicContact CD1-CD1 4.21Å; I487-L501 HydrophobicContact CG1-CD1 3.95Å; I497-L501 HydrophobicContact CG2-CD1 3.97Å; I497-L501 HydrophobicContact CG2-CG 4.41Å; I497-L501 VanDerWaalsContact O-CG 3.31Å; I497-L501 WeakPolarHBondContact O-CG 3.16Å; I497-L501 PolarHBondContact O-N 3.37Å; R498-L501 PolarHBondContact O-N 3.45Å; L501-R503 VanDerWaalsContact C-N 3.31Å; L501-R503 PolarHBondContact O-N 3.41Å; L501-Y504 PolarHBondContact O-N 2.96Å; L501-I505 WeakPolarHBondContact O-CG1 3.28Å; L501-I505 PolarHBondContact O-N 3.06Å; L501-I505 VanDerWaalsContact O-N 3.11Å; L501-A565 HydrophobicContact CD2-CB 3.98Å; L501-A565 WeakPolarHBondContact CD2-O 3.41Å; L501-L568 HydrophobicContact CD2-CB 4.05Å; L501-L568 HydrophobicContact CD2-CD2 3.86Å; L501-L568 HydrophobicContact CD2-CG 4.01Å; L501-L568 HydrophobicContact CG-CD2 3.91Å; L501-L568 HydrophobicContact CG-CG 4.32Å; L501-V569 HydrophobicContact CD1-CG2 4.03Å; L501-V569 HydrophobicContact CD2-CG2 3.6Å; L501-V569 HydrophobicContact CG-CG2 4.5Å
502V97.5Very high96.1Very high1 Ų113 Ų131%0.0066%0.056CC..Hα-helixtrans-68.8-31.6179-62.90000112.3A480 V483 R498 R499 I505 N506 C691 Y692 V695A480-V502 HydrophobicContact CB-CG1 3.99Å; V483-V502 HydrophobicContact CG1-CG1 4.47Å; R498-V502 PolarHBondContact O-N 3.25Å; R499-V502 VanDerWaalsContact O-CG2 3.3Å; R499-V502 WeakPolarHBondContact O-CG2 3.42Å; V502-I505 PolarHBondContact O-N 3.01Å; V502-N506 PolarHBondContact O-N 2.86Å; V502-N506 PolarHBondContact O-ND2 2.95Å; V502-C691 HydrophobicContact CB-CB 3.71Å; V502-C691 HydrophobicContact CG1-CB 4.19Å; V502-C691 HydrophobicContact CG2-CB 3.81Å; V502-Y692 HydrophobicContact CG2-CD1 4.04Å; V502-Y692 HydrophobicContact CG2-CE1 4.09Å; V502-V695 HydrophobicContact CG1-CG1 3.66Å; V502-V695 HydrophobicContact CG2-CG1 4.39Å; V502-V695 HydrophobicContact CG2-CG2 3.95Å
503R97.3Very high96.2Very high3 Ų39 Ų91%0.0114%0.038CC..Hα-helixtrans-65.7-43.8174.1-175.3174.658.579.9-4.3111.8R499 T500 L501 I505 N506 L507 G534 F535 E540 Y692R499-R503 VanDerWaalsContact O-CB 3.23Å; R499-R503 WeakPolarHBondContact O-CB 3.24Å; R499-R503 PolarHBondContact O-N 3.47Å; T500-R503 PolarHBondContact O-N 3.04Å; L501-R503 VanDerWaalsContact C-N 3.31Å; L501-R503 PolarHBondContact O-N 3.41Å; R503-I505 PolarHBondContact O-N 3.36Å; R503-N506 PolarHBondContact O-N 3.31Å; R503-L507 VanDerWaalsContact O-CB 3.26Å; R503-L507 WeakPolarHBondContact O-CB 3.08Å; R503-L507 PolarHBondContact O-N 3.31Å; R503-G534 VanDerWaalsContact CD-O 3.29Å; R503-G534 WeakPolarHBondContact CD-O 3.45Å; R503-F535 WeakPolarHBondContact CD-O 3.41Å; R503-F535 VanDerWaalsContact CG-O 3.22Å; R503-F535 WeakPolarHBondContact CG-O 3.4Å; R503-F535 PolarHBondContact NH1-O 3.12Å; R503-E540 IonicContact CZ-OE1 3.81Å; R503-E540 IonicContact CZ-OE2 2.95Å; R503-E540 IonicContact NH1-OE1 2.7Å; R503-E540 IonicContact NH1-OE2 2.88Å; R503-E540 PolarHBondContact NH1-OE2 3.27Å; R503-E540 IonicContact NH2-OE1 3.42Å; R503-E540 PolarHBondContact NH2-OE1 2.79Å; R503-E540 IonicContact NH2-OE2 2.64Å; R503-E540 PolarHBondContact NH2-OE2 3.05Å; R503-Y692 WeakPolarHBondContact CD-OH 3.15Å
504Y98.4Very high96.1Very high1 Ų17 Ų70%0.0043%0.03CC..Hα-helixtrans-63.2-39175.3-73.1-12.8000113.3T500 L501 L507 S508 E540 P561 W564 A565T500-Y504 HydrophobicContact CG2-CD1 4.32Å; T500-Y504 HydrophobicContact CG2-CD2 3.91Å; T500-Y504 HydrophobicContact CG2-CE1 3.89Å; T500-Y504 HydrophobicContact CG2-CE2 3.44Å; T500-Y504 VanDerWaalsContact CG2-CE2 3.44Å; T500-Y504 HydrophobicContact CG2-CG 4.33Å; T500-Y504 VanDerWaalsContact CG2-CZ 3.41Å; T500-Y504 PolarHBondContact O-N 3.48Å; L501-Y504 PolarHBondContact O-N 2.96Å; Y504-L507 PolarHBondContact O-N 3.03Å; Y504-S508 PolarHBondContact O-N 3.12Å; Y504-E540 WeakPolarHBondContact CE1-OE1 3.47Å; Y504-E540 VanDerWaalsContact CZ-OE1 3.31Å; Y504-E540 PolarHBondContact OH-OE1 3.35Å; Y504-P561 WeakPolarHBondContact CB-O 3.16Å; Y504-P561 HydrophobicContact CG-CB 4.45Å; Y504-W564 HydrophobicContact CD1-CE3 4.41Å; Y504-W564 HydrophobicContact CD2-CB 3.81Å; Y504-W564 HydrophobicContact CE1-CE3 4.01Å; Y504-W564 HydrophobicContact CE2-CB 3.56Å; Y504-W564 HydrophobicContact CE2-CE3 4.44Å; Y504-A565 HydrophobicContact CD2-CB 4.14Å
505I98.1Very high95.9Very high1 Ų110.3 Ų10.31%0.0055%0.048CC..Hα-helixtrans-59.5-48.6173.1-70.2168.6000110.9P476 A479 L501 V502 R503 T509 L562 I591 I594P476-I505 HydrophobicContact CB-CG2 3.88Å; A479-I505 HydrophobicContact CB-CD1 3.88Å; L501-I505 WeakPolarHBondContact O-CG1 3.28Å; L501-I505 PolarHBondContact O-N 3.06Å; L501-I505 VanDerWaalsContact O-N 3.11Å; V502-I505 PolarHBondContact O-N 3.01Å; R503-I505 PolarHBondContact O-N 3.36Å; I505-T509 PolarHBondContact O-N 2.94Å; I505-T509 PolarHBondContact O-OG1 3.16Å; I505-L562 HydrophobicContact CG1-CD2 4.13Å; I505-I591 HydrophobicContact CD1-CG1 4.2Å; I505-I594 HydrophobicContact CD1-CD1 4.31Å; I505-I594 HydrophobicContact CG2-CD1 3.61Å; I505-I594 HydrophobicContact CG2-CG2 4.16Å
506N97.6Very high95.7Very high8 Ų88.3 Ų8.34%0.0434%0.041CC..Hα-helixtrans-67.6-39.1179-79.3-71.4000112.3V502 R503 T509 L510 F535 N687 L688 C691V502-N506 PolarHBondContact O-N 2.86Å; V502-N506 PolarHBondContact O-ND2 2.95Å; R503-N506 PolarHBondContact O-N 3.31Å; N506-T509 PolarHBondContact O-N 3.44Å; N506-L510 WeakPolarHBondContact O-CB 3.33Å; N506-L510 PolarHBondContact O-N 3.43Å; N506-F535 HydrophobicContact CB-CD1 4.36Å; N506-F535 HydrophobicContact CB-CE1 4.13Å; N506-N687 WeakPolarHBondContact OD1-CB 3.29Å; N506-L688 HydrophobicContact CB-CD1 4.25Å; N506-C691 PolarHBondContact ND2-SG 2.95Å; N506-C691 VanDerWaalsContact ND2-SG 3.41Å
507L97.9Very high95.4Very high0 Ų07.5 Ų7.50%04%0.038CC..Hα-helixtrans-61.8-47.2177.9174.662.1000111.9R503 Y504 T509 L510 F511 L530 F535 I536 P561R503-L507 VanDerWaalsContact O-CB 3.26Å; R503-L507 WeakPolarHBondContact O-CB 3.08Å; R503-L507 PolarHBondContact O-N 3.31Å; Y504-L507 PolarHBondContact O-N 3.03Å; L507-T509 VanDerWaalsContact C-N 3.32Å; L507-T509 PolarHBondContact O-N 2.96Å; L507-L510 PolarHBondContact O-N 3.33Å; L507-L510 VanDerWaalsContact O-N 3.17Å; L507-F511 HydrophobicContact CD1-CD1 4.31Å; L507-F511 HydrophobicContact CD1-CE1 3.78Å; L507-F511 HydrophobicContact CD1-CE2 4.29Å; L507-F511 HydrophobicContact CD1-CZ 3.77Å; L507-F511 HydrophobicContact CD2-CZ 4.41Å; L507-F511 HydrophobicContact CG-CE1 4.47Å; L507-F511 HydrophobicContact CG-CE2 4.11Å; L507-F511 HydrophobicContact CG-CZ 4.05Å; L507-F511 PolarHBondContact O-N 3.42Å; L507-L530 HydrophobicContact CD1-CD2 3.61Å; L507-F535 HydrophobicContact CD1-CB 3.99Å; L507-I536 HydrophobicContact CD1-CB 4.02Å; L507-I536 HydrophobicContact CD2-CB 3.86Å; L507-I536 HydrophobicContact CD2-CD1 4Å; L507-I536 HydrophobicContact CD2-CG1 3.9Å; L507-P561 HydrophobicContact CD2-CB 4.06Å; L507-P561 HydrophobicContact CD2-CG 3.82Å; L507-P561 HydrophobicContact CG-CB 4.34Å; L507-P561 HydrophobicContact CG-CG 3.98Å
508S97.4Very high94.7Very high0 Ų09.4 Ų9.40%05%0.049CC..Hα-helixtrans-63.2-39.5177.3-175.90000112.1Y504 F511 V512 F558 L562 I598Y504-S508 PolarHBondContact O-N 3.12Å; S508-F511 PolarHBondContact O-N 3.41Å; S508-V512 PolarHBondContact O-N 3.47Å; S508-F558 WeakPolarHBondContact CB-O 3.31Å; S508-F558 PolarHBondContact OG-O 3.45Å; S508-L562 WeakPolarHBondContact OG-CD1 3.47Å; S508-L562 WeakPolarHBondContact OG-CG 3.36Å; S508-I598 WeakPolarHBondContact OG-CD1 3.43Å
509T97.2Very high93.9Very high10 Ų109.4 Ų9.46%0.0615%0.051CC..Hα-helixtrans-62.4-44.2172.7-55.10000110.9I505 N506 L507 F511 V512 L513 I598I505-T509 PolarHBondContact O-N 2.94Å; I505-T509 PolarHBondContact O-OG1 3.16Å; N506-T509 PolarHBondContact O-N 3.44Å; L507-T509 VanDerWaalsContact C-N 3.32Å; L507-T509 PolarHBondContact O-N 2.96Å; T509-F511 PolarHBondContact O-N 3.25Å; T509-V512 PolarHBondContact O-N 3.42Å; T509-L513 HydrophobicContact CG2-CD1 3.93Å; T509-L513 HydrophobicContact CG2-CG 4.21Å; T509-L513 WeakPolarHBondContact O-CG 3.46Å; T509-L513 PolarHBondContact O-N 2.68Å; T509-I598 HydrophobicContact CG2-CG2 4.26Å
510L96.2Very high93.5Very high2 Ų29.4 Ų9.41%0.015%0.05CC..Hα-helixtrans-64.7-36.9179.9179.457.5000112.6N506 L507 V512 L513 R514 V520 F524 L530 F535 I684N506-L510 WeakPolarHBondContact O-CB 3.33Å; N506-L510 PolarHBondContact O-N 3.43Å; L507-L510 PolarHBondContact O-N 3.33Å; L507-L510 VanDerWaalsContact O-N 3.17Å; L510-V512 VanDerWaalsContact C-N 3.33Å; L510-V512 PolarHBondContact O-N 3.48Å; L510-L513 PolarHBondContact O-N 2.77Å; L510-R514 WeakPolarHBondContact O-CB 3.36Å; L510-R514 PolarHBondContact O-N 2.94Å; L510-V520 HydrophobicContact CD1-CG1 3.75Å; L510-F524 HydrophobicContact CD1-CD2 3.68Å; L510-F524 HydrophobicContact CD1-CE2 3.72Å; L510-F524 HydrophobicContact CD1-CG 4.38Å; L510-F524 HydrophobicContact CD1-CZ 4.46Å; L510-F524 HydrophobicContact CD2-CD2 4.44Å; L510-F524 HydrophobicContact CD2-CE1 4.42Å; L510-F524 HydrophobicContact CD2-CE2 4.34Å; L510-F524 HydrophobicContact CD2-CZ 4.33Å; L510-L530 HydrophobicContact CD2-CD2 3.63Å; L510-L530 HydrophobicContact CD2-CG 4.1Å; L510-L530 HydrophobicContact CG-CD2 3.98Å; L510-F535 HydrophobicContact CD2-CB 4.25Å; L510-F535 HydrophobicContact CD2-CD1 3.87Å; L510-F535 HydrophobicContact CD2-CD2 3.54Å; L510-F535 HydrophobicContact CD2-CE1 4.05Å; L510-F535 HydrophobicContact CD2-CE2 3.74Å; L510-F535 HydrophobicContact CD2-CG 3.61Å; L510-F535 HydrophobicContact CD2-CZ 4Å; L510-I684 HydrophobicContact CD1-CD1 3.69Å; L510-I684 HydrophobicContact CD1-CG1 4.33Å; L510-I684 HydrophobicContact CD1-CG2 4.5Å
511F94.5Very high93Very high5 Ų513 Ų132%0.0227%0.066CC..Hα-helixtrans-55.1-50.2173.4-73.6-28.2000111.4L507 S508 T509 D515 M527 L530 I536 F544 F558 P561L507-F511 HydrophobicContact CD1-CD1 4.31Å; L507-F511 HydrophobicContact CD1-CE1 3.78Å; L507-F511 HydrophobicContact CD1-CE2 4.29Å; L507-F511 HydrophobicContact CD1-CZ 3.77Å; L507-F511 HydrophobicContact CD2-CZ 4.41Å; L507-F511 HydrophobicContact CG-CE1 4.47Å; L507-F511 HydrophobicContact CG-CE2 4.11Å; L507-F511 HydrophobicContact CG-CZ 4.05Å; L507-F511 PolarHBondContact O-N 3.42Å; S508-F511 PolarHBondContact O-N 3.41Å; T509-F511 PolarHBondContact O-N 3.25Å; F511-D515 PolarHBondContact O-N 3.06Å; F511-M527 HydrophobicContact CD1-CE 4.38Å; F511-M527 HydrophobicContact CD1-SD 4.5Å; F511-M527 HydrophobicContact CE1-CE 4.21Å; F511-M527 HydrophobicContact CE1-SD 3.76Å; F511-L530 HydrophobicContact CD1-CD2 3.95Å; F511-L530 HydrophobicContact CE1-CD2 3.77Å; F511-I536 HydrophobicContact CZ-CD1 4.49Å; F511-F544 HydrophobicContact CD2-CE2 4.41Å; F511-F544 HydrophobicContact CE2-CD2 4.13Å; F511-F544 AromaticContact CE2-CE2 3.58Å; F511-F544 HydrophobicContact CE2-CE2 3.58Å; F511-F544 AromaticContact CE2-CZ 3.9Å; F511-F544 HydrophobicContact CE2-CZ 3.9Å; F511-F544 HydrophobicContact CZ-CD2 4.23Å; F511-F544 HydrophobicContact CZ-CE1 4.3Å; F511-F544 AromaticContact CZ-CE2 3.9Å; F511-F544 HydrophobicContact CZ-CE2 3.9Å; F511-F544 AromaticContact CZ-CZ 3.94Å; F511-F544 HydrophobicContact CZ-CZ 3.94Å; F511-F558 HydrophobicContact CB-CB 4.11Å; F511-P561 HydrophobicContact CD2-CG 4.1Å; F511-P561 HydrophobicContact CE2-CG 3.58Å
512V94.6Very high92.2Very high0 Ų017.1 Ų17.10%08%0.084CC..Hα-helixtrans-64.7-48.9177.9178.70000111.6S508 T509 L510 R514 D515 I516 Y556 F558 I598 L601S508-V512 PolarHBondContact O-N 3.47Å; T509-V512 PolarHBondContact O-N 3.42Å; L510-V512 VanDerWaalsContact C-N 3.33Å; L510-V512 PolarHBondContact O-N 3.48Å; V512-R514 VanDerWaalsContact C-N 3.3Å; V512-R514 PolarHBondContact O-N 3.2Å; V512-D515 PolarHBondContact O-N 3.39Å; V512-D515 VanDerWaalsContact O-N 3.1Å; V512-I516 HydrophobicContact CG1-CD1 4.05Å; V512-I516 HydrophobicContact CG1-CG2 4.41Å; V512-I516 WeakPolarHBondContact O-CG1 3.43Å; V512-I516 PolarHBondContact O-N 3.35Å; V512-I516 VanDerWaalsContact O-N 3.1Å; V512-Y556 WeakPolarHBondContact CA-OH 3.32Å; V512-F558 HydrophobicContact CG2-CB 3.74Å; V512-F558 HydrophobicContact CG2-CD1 4.41Å; V512-F558 HydrophobicContact CG2-CD2 3.64Å; V512-F558 HydrophobicContact CG2-CE2 4.4Å; V512-F558 HydrophobicContact CG2-CG 3.66Å; V512-I598 HydrophobicContact CG2-CB 4.34Å; V512-L601 HydrophobicContact CG1-CB 4.43Å; V512-L601 HydrophobicContact CG1-CD2 4.37Å
513L94.3Very high91.6Very high4 Ų417.2 Ų17.22%0.0218%0.084CC..Hα-helixtrans-61.6-37.8-178.6-67.8-177.8000112.6T509 L510 D515 I516 S517 V520 L601 L680 I684T509-L513 HydrophobicContact CG2-CD1 3.93Å; T509-L513 HydrophobicContact CG2-CG 4.21Å; T509-L513 WeakPolarHBondContact O-CG 3.46Å; T509-L513 PolarHBondContact O-N 2.68Å; L510-L513 PolarHBondContact O-N 2.77Å; L513-D515 VanDerWaalsContact C-N 3.27Å; L513-D515 PolarHBondContact O-N 2.85Å; L513-I516 HydrophobicContact CD2-CD1 4.39Å; L513-S517 VanDerWaalsContact O-CB 3.23Å; L513-S517 WeakPolarHBondContact O-CB 3.37Å; L513-S517 PolarHBondContact O-N 2.86Å; L513-V520 HydrophobicContact CB-CG1 4.3Å; L513-V520 HydrophobicContact CB-CG2 4.42Å; L513-L601 HydrophobicContact CD2-CD2 3.76Å; L513-L680 HydrophobicContact CD1-CD2 4.43Å; L513-L680 HydrophobicContact CD2-CD1 3.89Å; L513-L680 HydrophobicContact CD2-CD2 4.03Å; L513-I684 HydrophobicContact CD1-CD1 4.06Å; L513-I684 HydrophobicContact CD1-CG1 3.9Å
514R90.8Very high91.1Very high27 Ų2717 Ų1710%0.1028%0.084CC..Hα-helixtrans-60.8-37.9175.7174.4-175.2165.4-99.19.3111.5L510 V512 V520 K521 F524 P525L510-R514 WeakPolarHBondContact O-CB 3.36Å; L510-R514 PolarHBondContact O-N 2.94Å; V512-R514 VanDerWaalsContact C-N 3.3Å; V512-R514 PolarHBondContact O-N 3.2Å; R514-V520 HydrophobicContact CB-CG1 4.2Å; R514-K521 HydrophobicContact CG-CD 3.73Å; R514-K521 WeakPolarHBondContact O-CB 3.44Å; R514-K521 WeakPolarHBondContact O-CD 3.04Å; R514-F524 WeakPolarHBondContact CD-O 3.28Å; R514-F524 HydrophobicContact CG-CB 4.49Å; R514-F524 WeakPolarHBondContact CG-O 3.2Å; R514-F524 PolarHBondContact NE-O 3.17Å; R514-P525 PolarHBondContact NH2-O 3.32Å
515D88.9Confident90.3Very high69 Ų6919.4 Ų19.437%0.36910%0.099SC..Hα-helixtrans-88.6-19.9-173.2-67-23.6000113.5F511 V512 L513 K521F511-D515 PolarHBondContact O-N 3.06Å; V512-D515 PolarHBondContact O-N 3.39Å; V512-D515 VanDerWaalsContact O-N 3.1Å; L513-D515 VanDerWaalsContact C-N 3.27Å; L513-D515 PolarHBondContact O-N 2.85Å; D515-K521 IonicContact OD1-NZ 2.6Å; D515-K521 PolarHBondContact OD1-NZ 3.02Å
516I90.1Very high89.7Confident15 Ų1522 Ų228%0.07712%0.115CC..Hα-helixtrans-102.9-18.417773.8-176.7000114.4V512 L513 L601 D605 F671V512-I516 HydrophobicContact CG1-CD1 4.05Å; V512-I516 HydrophobicContact CG1-CG2 4.41Å; V512-I516 WeakPolarHBondContact O-CG1 3.43Å; V512-I516 PolarHBondContact O-N 3.35Å; V512-I516 VanDerWaalsContact O-N 3.1Å; L513-I516 HydrophobicContact CD2-CD1 4.39Å; I516-L601 HydrophobicContact CD1-CD2 3.76Å; I516-L601 HydrophobicContact CD1-CG 3.74Å; I516-D605 HydrophobicContact CB-CB 4.1Å; I516-D605 HydrophobicContact CG2-CB 3.6Å; I516-F671 HydrophobicContact CB-CD2 4.41Å; I516-F671 HydrophobicContact CD1-CD2 3.94Å; I516-F671 HydrophobicContact CD1-CE1 4.19Å; I516-F671 HydrophobicContact CD1-CE2 3.54Å; I516-F671 HydrophobicContact CD1-CG 4.42Å; I516-F671 HydrophobicContact CD1-CZ 3.65Å; I516-F671 HydrophobicContact CG1-CD2 4.01Å; I516-F671 HydrophobicContact CG1-CE2 4.14Å; I516-F671 HydrophobicContact CG1-CG 4.27Å; I516-F671 HydrophobicContact CG1-CZ 4.48Å; I516-F671 WeakPolarHBondContact O-CB 3.32Å
517S88.6Confident89.3Confident3 Ų323.9 Ų23.92%0.02112%0.124CC..  trans-111.9125-179.2177.80000112.7L513 A519 V520 K521 F671L513-S517 VanDerWaalsContact O-CB 3.23Å; L513-S517 WeakPolarHBondContact O-CB 3.37Å; L513-S517 PolarHBondContact O-N 2.86Å; S517-A519 VanDerWaalsContact C-N 3.33Å; S517-A519 PolarHBondContact O-N 3.49Å; S517-A519 PolarHBondContact OG-N 3.34Å; S517-V520 PolarHBondContact O-N 2.95Å; S517-V520 PolarHBondContact OG-N 3.25Å; S517-K521 WeakPolarHBondContact O-CB 3.27Å; S517-K521 PolarHBondContact O-N 3.17Å; S517-F671 WeakPolarHBondContact CA-O 3.13Å; S517-F671 WeakPolarHBondContact CB-O 3.14Å; S517-F671 PolarHBondContact OG-O 2.9Å
518T82.3Confident88.8Confident41 Ų4129.8 Ų29.825%0.25215%0.152SC..Hα-helixtrans-63.9-40.417554.60000111.4A10 V520 K521 K522 F671 E673A10-T518 HydrophobicContact CB-CG2 3.68Å; T518-V520 VanDerWaalsContact C-N 3.34Å; T518-V520 PolarHBondContact O-N 2.85Å; T518-K521 PolarHBondContact O-N 3.35Å; T518-K522 WeakPolarHBondContact O-CG 3.29Å; T518-K522 PolarHBondContact O-N 3.01Å; T518-F671 PolarHBondContact N-O 2.98Å; T518-E673 PolarHBondContact OG1-OE1 3.15Å
519A80.6Confident88.4Confident6 Ų632.5 Ų32.55%0.0516%0.164CC..Hα-helixtrans-61.3-39.7177.500000112.7L354 S517 E673 N681L354-A519 HydrophobicContact CD1-CB 3.92Å; S517-A519 VanDerWaalsContact C-N 3.33Å; S517-A519 PolarHBondContact O-N 3.49Å; S517-A519 PolarHBondContact OG-N 3.34Å; A519-E673 HydrophobicContact CB-CG 4.1Å; A519-N681 PolarHBondContact O-ND2 2.91Å
520V86.4Confident88.2Confident0 Ų032 Ų320%016%0.161CC..Hα-helixtrans-77.2-39177.4-1770000110.8L510 L513 R514 S517 T518 K522 R523 F524 L680 I684L510-V520 HydrophobicContact CD1-CG1 3.75Å; L513-V520 HydrophobicContact CB-CG1 4.3Å; L513-V520 HydrophobicContact CB-CG2 4.42Å; R514-V520 HydrophobicContact CB-CG1 4.2Å; S517-V520 PolarHBondContact O-N 2.95Å; S517-V520 PolarHBondContact OG-N 3.25Å; T518-V520 VanDerWaalsContact C-N 3.34Å; T518-V520 PolarHBondContact O-N 2.85Å; V520-K522 VanDerWaalsContact C-N 3.29Å; V520-K522 PolarHBondContact O-N 2.97Å; V520-R523 WeakPolarHBondContact O-CA 3.49Å; V520-R523 WeakPolarHBondContact O-CB 3.36Å; V520-R523 PolarHBondContact O-N 3.46Å; V520-F524 HydrophobicContact CG1-CD2 3.78Å; V520-F524 HydrophobicContact CG1-CE2 4.23Å; V520-F524 PolarHBondContact O-N 2.86Å; V520-L680 HydrophobicContact CG2-CB 3.6Å; V520-L680 HydrophobicContact CG2-CD1 3.98Å; V520-L680 HydrophobicContact CG2-CG 4.49Å; V520-I684 HydrophobicContact CB-CD1 4.46Å; V520-I684 HydrophobicContact CG1-CD1 3.69Å; V520-I684 HydrophobicContact CG2-CD1 3.84Å
521K86.2Confident88Confident78 Ų7832.9 Ų32.934%0.33917%0.167SC..Hα-helixtrans-59.5-39175-166.865.1161.2-156.40112.4R514 D515 S517 T518 R523 F524 P525R514-K521 HydrophobicContact CG-CD 3.73Å; R514-K521 WeakPolarHBondContact O-CB 3.44Å; R514-K521 WeakPolarHBondContact O-CD 3.04Å; D515-K521 IonicContact OD1-NZ 2.6Å; D515-K521 PolarHBondContact OD1-NZ 3.02Å; S517-K521 WeakPolarHBondContact O-CB 3.27Å; S517-K521 PolarHBondContact O-N 3.17Å; T518-K521 PolarHBondContact O-N 3.35Å; K521-R523 PolarHBondContact O-N 2.99Å; K521-F524 CarbonylContact O-C 3.55Å; K521-F524 VanDerWaalsContact O-C 3.31Å; K521-F524 PolarHBondContact O-N 3.46Å; K521-P525 VanDerWaalsContact O-CA 3.23Å; K521-P525 WeakPolarHBondContact O-CA 3.49Å; K521-P525 VanDerWaalsContact O-N 3.09Å
522K81.9Confident87.5Confident85 Ų8538.1 Ų38.137%0.3719%0.191SC..Hα-helixtrans-61.7-32.4173.7-77.3177.1177.8175.70112.4T348 A350 L354 T518 V520 E673T348-K522 PolarHBondContact OG1-O 3.21Å; A350-K522 HydrophobicContact CB-CB 4.44Å; L354-K522 HydrophobicContact CD1-CD 4.32Å; T518-K522 WeakPolarHBondContact O-CG 3.29Å; T518-K522 PolarHBondContact O-N 3.01Å; V520-K522 VanDerWaalsContact C-N 3.29Å; V520-K522 PolarHBondContact O-N 2.97Å; K522-E673 VanDerWaalsContact CE-OE1 3.24Å; K522-E673 WeakPolarHBondContact CE-OE1 3.11Å; K522-E673 IonicContact NZ-OE1 2.65Å; K522-E673 PolarHBondContact NZ-OE1 2.95Å; K522-E673 IonicContact NZ-OE2 3.58Å; K522-E673 PolarHBondContact NZ-OE2 2.64Å
523R85Confident87.2Confident3 Ų338.3 Ų38.31%0.01119%0.193CC..Hα-helixtrans-80.8-38.5178.1-172.9175.1179-168.17.7113I345 P346 H347 T348 S351 V520 K521 P525 N681 D685I345-R523 VanDerWaalsContact CB-NH2 3.28Å; I345-R523 PolarHBondContact O-NH2 2.88Å; P346-R523 PolarHBondContact O-NE 3.1Å; P346-R523 PolarHBondContact O-NH2 3.32Å; H347-R523 PolarHBondContact CE1-NE 3.21Å; H347-R523 PolarHBondContact NE2-NH2 2.94Å; T348-R523 VanDerWaalsContact CG2-O 3.28Å; T348-R523 WeakPolarHBondContact CG2-O 3.33Å; S351-R523 WeakPolarHBondContact OG-CA 3.48Å; V520-R523 WeakPolarHBondContact O-CA 3.49Å; V520-R523 WeakPolarHBondContact O-CB 3.36Å; V520-R523 PolarHBondContact O-N 3.46Å; K521-R523 PolarHBondContact O-N 2.99Å; R523-P525 VanDerWaalsContact C-CD 3.41Å; R523-P525 WeakPolarHBondContact O-CD 3.31Å; R523-N681 WeakPolarHBondContact CD-OD1 3.25Å; R523-N681 PolarHBondContact NH1-O 2.98Å; R523-D685 IonicContact CZ-OD1 2.68Å; R523-D685 IonicContact CZ-OD2 3.01Å; R523-D685 IonicContact NH1-OD1 3.83Å; R523-D685 PolarHBondContact NH1-OD1 3.3Å; R523-D685 IonicContact NH1-OD2 3.59Å; R523-D685 IonicContact NH2-OD1 2.97Å; R523-D685 PolarHBondContact NH2-OD1 3.33Å; R523-D685 IonicContact NH2-OD2 3.93Å; R523-D685 PolarHBondContact NH2-OD2 3.41Å
524F86.5Confident87Confident0 Ų038.3 Ų38.30%019%0.193CC..SBendtrans-124.566.7-178.4-52-79.4000110.8I345 L510 R514 V520 K521 H529 L530 S533 F535 I684I345-F524 HydrophobicContact CG2-CE1 4.13Å; I345-F524 HydrophobicContact CG2-CZ 4.1Å; L510-F524 HydrophobicContact CD1-CD2 3.68Å; L510-F524 HydrophobicContact CD1-CE2 3.72Å; L510-F524 HydrophobicContact CD1-CG 4.38Å; L510-F524 HydrophobicContact CD1-CZ 4.46Å; L510-F524 HydrophobicContact CD2-CD2 4.44Å; L510-F524 HydrophobicContact CD2-CE1 4.42Å; L510-F524 HydrophobicContact CD2-CE2 4.34Å; L510-F524 HydrophobicContact CD2-CZ 4.33Å; R514-F524 WeakPolarHBondContact CD-O 3.28Å; R514-F524 HydrophobicContact CG-CB 4.49Å; R514-F524 WeakPolarHBondContact CG-O 3.2Å; R514-F524 PolarHBondContact NE-O 3.17Å; V520-F524 HydrophobicContact CG1-CD2 3.78Å; V520-F524 HydrophobicContact CG1-CE2 4.23Å; V520-F524 PolarHBondContact O-N 2.86Å; K521-F524 CarbonylContact O-C 3.55Å; K521-F524 VanDerWaalsContact O-C 3.31Å; K521-F524 PolarHBondContact O-N 3.46Å; F524-H529 HydrophobicContact CB-CB 4.48Å; F524-H529 HydrophobicContact CD1-CB 4.32Å; F524-L530 HydrophobicContact CB-CD1 4.4Å; F524-S533 WeakPolarHBondContact CE1-OG 3.41Å; F524-F535 HydrophobicContact CE1-CD2 4.44Å; F524-F535 HydrophobicContact CE1-CE2 4.15Å; F524-F535 HydrophobicContact CZ-CE2 4.06Å; F524-I684 HydrophobicContact CE2-CD1 4.31Å; F524-I684 HydrophobicContact CE2-CG2 4.42Å; F524-I684 HydrophobicContact CZ-CG2 4.4Å
525P81.5Confident87.2Confident50 Ų5037.1 Ų37.133%0.32519%0.189SC..  trans-66.8-41.2-17424.6-33.6000112.2T348 R514 K521 R523T348-P525 HydrophobicContact CG2-CG 4.41Å; R514-P525 PolarHBondContact NH2-O 3.32Å; K521-P525 VanDerWaalsContact O-CA 3.23Å; K521-P525 WeakPolarHBondContact O-CA 3.49Å; K521-P525 VanDerWaalsContact O-N 3.09Å; R523-P525 VanDerWaalsContact C-CD 3.41Å; R523-P525 WeakPolarHBondContact O-CD 3.31Å
526T86.3Confident87.5Confident57 Ų5734 Ų3435%0.3517%0.172SC..SBendtrans-115.9163.4-178.573.80000111.7E528 H529 L530T526-E528 PolarHBondContact O-N 2.96Å; T526-H529 WeakPolarHBondContact O-CB 3.37Å; T526-H529 PolarHBondContact O-N 3.04Å; T526-H529 VanDerWaalsContact O-N 3.17Å; T526-H529 PolarHBondContact OG1-ND1 3.22Å; T526-L530 WeakPolarHBondContact O-CD1 3.23Å
527M87.7Confident87.7Confident46 Ų4634.8 Ų34.823%0.22718%0.178CC..Hα-helixtrans-63.3-30.6176-71-64.6131.300113F511 H529 L530 V531 L541F511-M527 HydrophobicContact CD1-CE 4.38Å; F511-M527 HydrophobicContact CD1-SD 4.5Å; F511-M527 HydrophobicContact CE1-CE 4.21Å; F511-M527 HydrophobicContact CE1-SD 3.76Å; M527-H529 PolarHBondContact O-N 2.92Å; M527-L530 HydrophobicContact CE-CD1 4.23Å; M527-L530 WeakPolarHBondContact O-CB 3.25Å; M527-L530 PolarHBondContact O-N 2.8Å; M527-L530 HydrophobicContact SD-CD1 3.99Å; M527-V531 PolarHBondContact O-N 3.48Å; M527-L541 HydrophobicContact CB-CD1 3.68Å; M527-L541 HydrophobicContact CB-CD2 4.06Å; M527-L541 HydrophobicContact CG-CD1 4.09Å; M527-L541 HydrophobicContact SD-CD1 4.48Å
528E88.7Confident87.9Confident125 Ų12541.8 Ų41.858%0.58421%0.21SC*.Hα-helixtrans-59.6-33174.5-61.7171.4158.500112.1T526 L530 V531 H532T526-E528 PolarHBondContact O-N 2.96Å; E528-L530 PolarHBondContact O-N 3.07Å; E528-V531 WeakPolarHBondContact O-CB 3.39Å; E528-V531 PolarHBondContact O-N 2.9Å; E528-V531 VanDerWaalsContact O-N 3.12Å; E528-H532 PolarHBondContact O-CD2 3.1Å; E528-H532 PolarHBondContact O-N 3.25Å
529H87.7Confident88.4Confident56 Ų5643.4 Ų43.426%0.25922%0.22SC..Hα-helixtrans-63.9-33.2175.1-69.672.7000111.3T348 F524 T526 M527 S533T348-H529 VanDerWaalsContact CG2-CD2 3.44Å; T348-H529 WeakPolarHBondContact CG2-CD2 3.45Å; T348-H529 WeakPolarHBondContact CG2-NE2 3.31Å; F524-H529 HydrophobicContact CB-CB 4.48Å; F524-H529 HydrophobicContact CD1-CB 4.32Å; T526-H529 WeakPolarHBondContact O-CB 3.37Å; T526-H529 PolarHBondContact O-N 3.04Å; T526-H529 VanDerWaalsContact O-N 3.17Å; T526-H529 PolarHBondContact OG1-ND1 3.22Å; M527-H529 PolarHBondContact O-N 2.92Å; H529-S533 WeakPolarHBondContact O-CB 3.34Å; H529-S533 PolarHBondContact O-N 3.05Å; H529-S533 PolarHBondContact O-OG 3.04Å
530L92.7Very high89.1Confident0 Ų043.2 Ų43.20%022%0.218CC..Hα-helixtrans-69.7-34.1174.7-6896.5000111.9L507 L510 F511 F524 T526 M527 E528 G534 F535 I536L507-L530 HydrophobicContact CD1-CD2 3.61Å; L510-L530 HydrophobicContact CD2-CD2 3.63Å; L510-L530 HydrophobicContact CD2-CG 4.1Å; L510-L530 HydrophobicContact CG-CD2 3.98Å; F511-L530 HydrophobicContact CD1-CD2 3.95Å; F511-L530 HydrophobicContact CE1-CD2 3.77Å; F524-L530 HydrophobicContact CB-CD1 4.4Å; T526-L530 WeakPolarHBondContact O-CD1 3.23Å; M527-L530 HydrophobicContact CE-CD1 4.23Å; M527-L530 WeakPolarHBondContact O-CB 3.25Å; M527-L530 PolarHBondContact O-N 2.8Å; M527-L530 HydrophobicContact SD-CD1 3.99Å; E528-L530 PolarHBondContact O-N 3.07Å; L530-G534 PolarHBondContact O-N 3.03Å; L530-F535 HydrophobicContact CB-CB 4.38Å; L530-F535 PolarHBondContact O-N 3.27Å; L530-I536 HydrophobicContact CB-CG2 3.79Å; L530-I536 PolarHBondContact O-N 3.34Å
531V91.9Very high89.5Confident21 Ų2144.3 Ų44.313%0.12722%0.224CC..Hα-helixtrans-66.6-52.6173.6177.40000110.4M527 E528 S533 G534 I536 E538 L541M527-V531 PolarHBondContact O-N 3.48Å; E528-V531 WeakPolarHBondContact O-CB 3.39Å; E528-V531 PolarHBondContact O-N 2.9Å; E528-V531 VanDerWaalsContact O-N 3.12Å; V531-S533 PolarHBondContact O-N 2.94Å; V531-G534 PolarHBondContact O-N 2.9Å; V531-I536 WeakPolarHBondContact CA-O 3.25Å; V531-I536 HydrophobicContact CB-CG2 4.49Å; V531-I536 HydrophobicContact CG2-CG2 3.65Å; V531-E538 HydrophobicContact CG1-CG 3.71Å; V531-L541 HydrophobicContact CG2-CB 4.12Å; V531-L541 HydrophobicContact CG2-CD2 3.48Å; V531-L541 VanDerWaalsContact CG2-CD2 3.48Å; V531-L541 HydrophobicContact CG2-CG 4.4Å
532H85.6Confident89.8Confident115 Ų11543.9 Ų43.953%0.53223%0.231SC..Hα-helixtrans-61.8-29.4178.2-68.8-48.3000112.7K336 E528 G534K336-H532 WeakPolarHBondContact CD-O 3.46Å; K336-H532 WeakPolarHBondContact CE-O 3.32Å; K336-H532 PolarHBondContact NZ-O 2.6Å; E528-H532 PolarHBondContact O-CD2 3.1Å; E528-H532 PolarHBondContact O-N 3.25Å; H532-G534 VanDerWaalsContact C-N 3.34Å
533S88.6Confident90.2Very high4 Ų442.3 Ų42.33%0.02823%0.226CC..THydrogen-bonded Turntrans-84.5-1.6174.4-72.10000114.7H337 I345 F524 H529 V531 F535H337-S533 PolarHBondContact NE2-O 3.49Å; H337-S533 VanDerWaalsContact NE2-O 3.11Å; I345-S533 WeakPolarHBondContact CG2-OG 3.28Å; F524-S533 WeakPolarHBondContact CE1-OG 3.41Å; H529-S533 WeakPolarHBondContact O-CB 3.34Å; H529-S533 PolarHBondContact O-N 3.05Å; H529-S533 PolarHBondContact O-OG 3.04Å; V531-S533 PolarHBondContact O-N 2.94Å; S533-F535 VanDerWaalsContact C-N 3.33Å; S533-F535 PolarHBondContact O-N 3.11Å
534G90Very high90.4Very high4 Ų443.1 Ų43.14%0.04123%0.23CC..THydrogen-bonded Turntrans75.115.2175.500000115.4R503 L530 V531 H532R503-G534 VanDerWaalsContact CD-O 3.29Å; R503-G534 WeakPolarHBondContact CD-O 3.45Å; L530-G534 PolarHBondContact O-N 3.03Å; V531-G534 PolarHBondContact O-N 2.9Å; H532-G534 VanDerWaalsContact C-N 3.34Å
535F94.7Very high90.5Very high1 Ų145.8 Ų45.80%0.00425%0.248CC..SBendtrans-78.9-33.5175.1-77.7-82.4000112.2I345 R503 N506 L507 L510 F524 L530 S533 I684 L688I345-F535 HydrophobicContact CD1-CE2 3.77Å; I345-F535 HydrophobicContact CD1-CZ 3.59Å; I345-F535 HydrophobicContact CG1-CE2 4.22Å; I345-F535 HydrophobicContact CG1-CZ 4.46Å; I345-F535 HydrophobicContact CG2-CE2 4.03Å; R503-F535 WeakPolarHBondContact CD-O 3.41Å; R503-F535 VanDerWaalsContact CG-O 3.22Å; R503-F535 WeakPolarHBondContact CG-O 3.4Å; R503-F535 PolarHBondContact NH1-O 3.12Å; N506-F535 HydrophobicContact CB-CD1 4.36Å; N506-F535 HydrophobicContact CB-CE1 4.13Å; L507-F535 HydrophobicContact CD1-CB 3.99Å; L510-F535 HydrophobicContact CD2-CB 4.25Å; L510-F535 HydrophobicContact CD2-CD1 3.87Å; L510-F535 HydrophobicContact CD2-CD2 3.54Å; L510-F535 HydrophobicContact CD2-CE1 4.05Å; L510-F535 HydrophobicContact CD2-CE2 3.74Å; L510-F535 HydrophobicContact CD2-CG 3.61Å; L510-F535 HydrophobicContact CD2-CZ 4Å; F524-F535 HydrophobicContact CE1-CD2 4.44Å; F524-F535 HydrophobicContact CE1-CE2 4.15Å; F524-F535 HydrophobicContact CZ-CE2 4.06Å; L530-F535 HydrophobicContact CB-CB 4.38Å; L530-F535 PolarHBondContact O-N 3.27Å; S533-F535 VanDerWaalsContact C-N 3.33Å; S533-F535 PolarHBondContact O-N 3.11Å; F535-I684 HydrophobicContact CE1-CG2 4.27Å; F535-I684 HydrophobicContact CE2-CG2 4.23Å; F535-I684 HydrophobicContact CZ-CG2 3.5Å; F535-I684 VanDerWaalsContact CZ-CG2 3.5Å; F535-L688 HydrophobicContact CD1-CD2 4.45Å; F535-L688 HydrophobicContact CE1-CB 4.32Å; F535-L688 HydrophobicContact CE1-CD1 4.21Å; F535-L688 HydrophobicContact CE1-CD2 3.92Å; F535-L688 HydrophobicContact CE1-CG 4.38Å; F535-L688 HydrophobicContact CE2-CD2 4.39Å; F535-L688 HydrophobicContact CZ-CB 4.43Å; F535-L688 HydrophobicContact CZ-CD2 3.88Å
536I95.6Very high90.8Very high3 Ų348.8 Ų48.82%0.01526%0.258CS..SBendtrans-133.8144.9178.7-165.5171.7000109.1L507 F511 L530 V531 E540 L541L507-I536 HydrophobicContact CD1-CB 4.02Å; L507-I536 HydrophobicContact CD2-CB 3.86Å; L507-I536 HydrophobicContact CD2-CD1 4Å; L507-I536 HydrophobicContact CD2-CG1 3.9Å; F511-I536 HydrophobicContact CZ-CD1 4.49Å; L530-I536 HydrophobicContact CB-CG2 3.79Å; L530-I536 PolarHBondContact O-N 3.34Å; V531-I536 WeakPolarHBondContact CA-O 3.25Å; V531-I536 HydrophobicContact CB-CG2 4.49Å; V531-I536 HydrophobicContact CG2-CG2 3.65Å; I536-E540 HydrophobicContact CD1-CB 4.05Å; I536-E540 HydrophobicContact CG1-CB 3.47Å; I536-E540 VanDerWaalsContact CG1-CB 3.47Å; I536-L541 HydrophobicContact CD1-CB 4.04Å; I536-L541 HydrophobicContact CD1-CD1 4.35Å; I536-L541 HydrophobicContact CG1-CB 4.39Å; I536-L541 HydrophobicContact CG2-CB 4.46Å
537T94.5Very high90.5Very high33 Ų3348.8 Ų48.820%0.20225%0.253CS..  trans-83.5164.2172.368.10000110.7T539 E540 L541T537-T539 VanDerWaalsContact C-N 3.29Å; T537-T539 PolarHBondContact O-N 3.41Å; T537-T539 PolarHBondContact OG1-OG1 3.32Å; T537-E540 PolarHBondContact N-OE2 3.48Å; T537-E540 PolarHBondContact O-N 2.9Å; T537-E540 WeakPolarHBondContact OG1-CB 3.05Å; T537-E540 WeakPolarHBondContact OG1-CG 3.45Å; T537-E540 PolarHBondContact OG1-N 3.02Å; T537-E540 VanDerWaalsContact OG1-N 3.11Å; T537-E540 PolarHBondContact OG1-OE2 2.92Å; T537-L541 WeakPolarHBondContact O-CB 3.37Å; T537-L541 PolarHBondContact O-N 3.2Å
538E92.3Very high90.2Very high150 Ų15048.2 Ų48.270%0.70125%0.252SS*.Hα-helixtrans-59.8-40.7174.6-68.8174.1-174.100112V531 E540 L541 S542V531-E538 HydrophobicContact CG1-CG 3.71Å; E538-E540 PolarHBondContact O-N 3.43Å; E538-L541 PolarHBondContact O-N 3.26Å; E538-S542 PolarHBondContact O-N 3.42Å
539T92.4Very high89.9Confident74 Ų7445.9 Ų45.945%0.45425%0.254SS..Hα-helixtrans-65.5-36.6176.852.20000112.8T537 S542 I543T537-T539 VanDerWaalsContact C-N 3.29Å; T537-T539 PolarHBondContact O-N 3.41Å; T537-T539 PolarHBondContact OG1-OG1 3.32Å; T539-S542 PolarHBondContact O-OG 3.04Å; T539-I543 WeakPolarHBondContact O-CD1 3.22Å; T539-I543 VanDerWaalsContact O-CG1 3.28Å; T539-I543 WeakPolarHBondContact O-CG1 3.46Å; T539-I543 PolarHBondContact O-N 2.85Å
540E95.4Very high89.5Confident2 Ų247.2 Ų47.21%0.00927%0.266CS..Hα-helixtrans-73.7-36.7175.9-72.4164169.700111.4P330 R503 Y504 I536 T537 E538 I543 F544 W564P330-E540 HydrophobicContact CB-CG 3.55Å; P330-E540 HydrophobicContact CG-CG 3.89Å; R503-E540 IonicContact CZ-OE1 3.81Å; R503-E540 IonicContact CZ-OE2 2.95Å; R503-E540 IonicContact NH1-OE1 2.7Å; R503-E540 IonicContact NH1-OE2 2.88Å; R503-E540 PolarHBondContact NH1-OE2 3.27Å; R503-E540 IonicContact NH2-OE1 3.42Å; R503-E540 PolarHBondContact NH2-OE1 2.79Å; R503-E540 IonicContact NH2-OE2 2.64Å; R503-E540 PolarHBondContact NH2-OE2 3.05Å; Y504-E540 WeakPolarHBondContact CE1-OE1 3.47Å; Y504-E540 VanDerWaalsContact CZ-OE1 3.31Å; Y504-E540 PolarHBondContact OH-OE1 3.35Å; I536-E540 HydrophobicContact CD1-CB 4.05Å; I536-E540 HydrophobicContact CG1-CB 3.47Å; I536-E540 VanDerWaalsContact CG1-CB 3.47Å; T537-E540 PolarHBondContact N-OE2 3.48Å; T537-E540 PolarHBondContact O-N 2.9Å; T537-E540 WeakPolarHBondContact OG1-CB 3.05Å; T537-E540 WeakPolarHBondContact OG1-CG 3.45Å; T537-E540 PolarHBondContact OG1-N 3.02Å; T537-E540 VanDerWaalsContact OG1-N 3.11Å; T537-E540 PolarHBondContact OG1-OE2 2.92Å; E538-E540 PolarHBondContact O-N 3.43Å; E540-I543 PolarHBondContact O-N 2.95Å; E540-F544 WeakPolarHBondContact O-CB 3.29Å; E540-F544 PolarHBondContact O-N 3.11Å; E540-W564 HydrophobicContact CB-CH2 4.48Å; E540-W564 HydrophobicContact CB-CZ3 4.26Å
541L94.3Very high88.6Confident24 Ų2449.9 Ų49.913%0.12628%0.277CS..Hα-helixtrans-66.8-38176.3179.460.6000111.6M527 V531 I536 T537 E538 F544 S545M527-L541 HydrophobicContact CB-CD1 3.68Å; M527-L541 HydrophobicContact CB-CD2 4.06Å; M527-L541 HydrophobicContact CG-CD1 4.09Å; M527-L541 HydrophobicContact SD-CD1 4.48Å; V531-L541 HydrophobicContact CG2-CB 4.12Å; V531-L541 HydrophobicContact CG2-CD2 3.48Å; V531-L541 VanDerWaalsContact CG2-CD2 3.48Å; V531-L541 HydrophobicContact CG2-CG 4.4Å; I536-L541 HydrophobicContact CD1-CB 4.04Å; I536-L541 HydrophobicContact CD1-CD1 4.35Å; I536-L541 HydrophobicContact CG1-CB 4.39Å; I536-L541 HydrophobicContact CG2-CB 4.46Å; T537-L541 WeakPolarHBondContact O-CB 3.37Å; T537-L541 PolarHBondContact O-N 3.2Å; E538-L541 PolarHBondContact O-N 3.26Å; L541-F544 PolarHBondContact O-N 3.28Å; L541-S545 VanDerWaalsContact O-CB 3.29Å; L541-S545 WeakPolarHBondContact O-CB 3.36Å; L541-S545 PolarHBondContact O-N 3.44Å; L541-S545 PolarHBondContact O-OG 3.41Å
542S92.5Very high87.3Confident69 Ų6954.6 Ų54.648%0.48330%0.301SS..Hα-helixtrans-63.4-46.5176.166.30000111.3E538 T539 F544 S545 E546E538-S542 PolarHBondContact O-N 3.42Å; T539-S542 PolarHBondContact O-OG 3.04Å; S542-F544 VanDerWaalsContact C-N 3.34Å; S542-F544 PolarHBondContact O-N 3.43Å; S542-S545 PolarHBondContact O-N 2.66Å; S542-E546 WeakPolarHBondContact O-CB 3.11Å; S542-E546 PolarHBondContact O-N 3.13Å
543I89.9Confident86.5Confident51 Ų5155.6 Ų55.626%0.26231%0.31SS..Hα-helixtrans-59.2-45.5174.5-64.6165.7000110.5P330 T539 E540 K547 W564P330-I543 HydrophobicContact CB-CD1 3.87Å; P330-I543 HydrophobicContact CG-CD1 4.19Å; T539-I543 WeakPolarHBondContact O-CD1 3.22Å; T539-I543 VanDerWaalsContact O-CG1 3.28Å; T539-I543 WeakPolarHBondContact O-CG1 3.46Å; T539-I543 PolarHBondContact O-N 2.85Å; E540-I543 PolarHBondContact O-N 2.95Å; I543-K547 VanDerWaalsContact O-CG 3.23Å; I543-K547 WeakPolarHBondContact O-CG 3.26Å; I543-K547 PolarHBondContact O-N 3.41Å; I543-W564 HydrophobicContact CG2-CZ2 4Å
544F90.2Very high85.6Confident21 Ų2161.9 Ų61.99%0.09234%0.337CS..Hα-helixtrans-61-47.6178-176.3-93.2000111.7F511 E540 L541 S542 K547 V548 M557 L560 W564F511-F544 HydrophobicContact CD2-CE2 4.41Å; F511-F544 HydrophobicContact CE2-CD2 4.13Å; F511-F544 AromaticContact CE2-CE2 3.58Å; F511-F544 HydrophobicContact CE2-CE2 3.58Å; F511-F544 AromaticContact CE2-CZ 3.9Å; F511-F544 HydrophobicContact CE2-CZ 3.9Å; F511-F544 HydrophobicContact CZ-CD2 4.23Å; F511-F544 HydrophobicContact CZ-CE1 4.3Å; F511-F544 AromaticContact CZ-CE2 3.9Å; F511-F544 HydrophobicContact CZ-CE2 3.9Å; F511-F544 AromaticContact CZ-CZ 3.94Å; F511-F544 HydrophobicContact CZ-CZ 3.94Å; E540-F544 WeakPolarHBondContact O-CB 3.29Å; E540-F544 PolarHBondContact O-N 3.11Å; L541-F544 PolarHBondContact O-N 3.28Å; S542-F544 VanDerWaalsContact C-N 3.34Å; S542-F544 PolarHBondContact O-N 3.43Å; F544-K547 PolarHBondContact O-N 3.47Å; F544-V548 HydrophobicContact CD1-CG2 3.92Å; F544-V548 HydrophobicContact CE1-CG2 3.51Å; F544-V548 HydrophobicContact CE2-CG2 4.4Å; F544-V548 HydrophobicContact CZ-CG2 3.77Å; F544-V548 WeakPolarHBondContact O-CG2 3.33Å; F544-V548 PolarHBondContact O-N 3.34Å; F544-M557 HydrophobicContact CE2-CB 3.96Å; F544-M557 HydrophobicContact CZ-CB 4.18Å; F544-L560 HydrophobicContact CD2-CD2 3.91Å; F544-L560 HydrophobicContact CE2-CD2 4.43Å; F544-W564 HydrophobicContact CB-CH2 4.18Å; F544-W564 HydrophobicContact CD2-CH2 4.49Å
545S89Confident84.8Confident55 Ų5562.1 Ų62.139%0.38534%0.338SS..Hα-helixtrans-69.5-42.8-174-55.40000112.4L541 S542 K547 V548 A549L541-S545 VanDerWaalsContact O-CB 3.29Å; L541-S545 WeakPolarHBondContact O-CB 3.36Å; L541-S545 PolarHBondContact O-N 3.44Å; L541-S545 PolarHBondContact O-OG 3.41Å; S542-S545 PolarHBondContact O-N 2.66Å; S545-K547 PolarHBondContact O-N 2.87Å; S545-V548 PolarHBondContact O-N 2.96Å; S545-A549 WeakPolarHBondContact O-CB 3.23Å; S545-A549 PolarHBondContact O-N 2.82Å
546E88Confident84.3Confident114 Ų11465.6 Ų65.653%0.53335%0.351SS..Hα-helixtrans-54.4-41.6173.2-173.8-155.2126.800110.7S542 T550S542-E546 WeakPolarHBondContact O-CB 3.11Å; S542-E546 PolarHBondContact O-N 3.13Å; E546-T550 PolarHBondContact O-N 2.97Å; E546-T550 VanDerWaalsContact O-N 3.13Å; E546-T550 PolarHBondContact O-OG1 3.01Å
547K80Confident83.9Confident56 Ų5665.8 Ų65.824%0.24335%0.352CS..Hα-helixtrans-76.2-40.9-178.9-63.4-61174.8-136.50113.1Y325 I543 F544 S545 A549 T550 Y551 M557Y325-K547 HydrophobicContact CE1-CG 4.4Å; Y325-K547 WeakPolarHBondContact OH-CB 3.25Å; Y325-K547 VanDerWaalsContact OH-CG 3.25Å; Y325-K547 WeakPolarHBondContact OH-CG 3.38Å; I543-K547 VanDerWaalsContact O-CG 3.23Å; I543-K547 WeakPolarHBondContact O-CG 3.26Å; I543-K547 PolarHBondContact O-N 3.41Å; F544-K547 PolarHBondContact O-N 3.47Å; S545-K547 PolarHBondContact O-N 2.87Å; K547-A549 VanDerWaalsContact C-N 3.26Å; K547-A549 PolarHBondContact O-N 3.32Å; K547-T550 WeakPolarHBondContact O-CB 3.18Å; K547-T550 PolarHBondContact O-N 3.1Å; K547-T550 VanDerWaalsContact O-N 3.11Å; K547-Y551 WeakPolarHBondContact O-CD2 3.42Å; K547-Y551 PolarHBondContact O-N 2.62Å; K547-M557 HydrophobicContact CB-CE 4.41Å; K547-M557 HydrophobicContact CB-SD 4.25Å; K547-M557 WeakPolarHBondContact O-CE 3.49Å
548V79.7Confident83.7Confident35 Ų3564.5 Ų64.521%0.21234%0.344CS..Hα-helixtrans-57.7-43.4172.7170.70000110.7F544 S545 T550 Y551 D552 M557F544-V548 HydrophobicContact CD1-CG2 3.92Å; F544-V548 HydrophobicContact CE1-CG2 3.51Å; F544-V548 HydrophobicContact CE2-CG2 4.4Å; F544-V548 HydrophobicContact CZ-CG2 3.77Å; F544-V548 WeakPolarHBondContact O-CG2 3.33Å; F544-V548 PolarHBondContact O-N 3.34Å; S545-V548 PolarHBondContact O-N 2.96Å; V548-T550 VanDerWaalsContact C-N 3.29Å; V548-T550 PolarHBondContact O-N 3.07Å; V548-Y551 PolarHBondContact O-N 2.88Å; V548-D552 PolarHBondContact O-N 3.23Å; V548-M557 HydrophobicContact CG2-CB 4.39Å; V548-M557 HydrophobicContact CG2-CG 4.33Å; V548-M557 HydrophobicContact CG2-SD 3.87Å
549A82.5Confident83.6Confident75 Ų7557.4 Ų57.462%0.6231%0.311SS*.Hα-helixtrans-61.9-34.6176.200000113.1S545 K547 Y551 D552S545-A549 WeakPolarHBondContact O-CB 3.23Å; S545-A549 PolarHBondContact O-N 2.82Å; K547-A549 VanDerWaalsContact C-N 3.26Å; K547-A549 PolarHBondContact O-N 3.32Å; A549-Y551 VanDerWaalsContact C-N 3.27Å; A549-Y551 PolarHBondContact O-N 2.76Å; A549-D552 PolarHBondContact O-N 2.76Å
550T80Confident83.6Confident84 Ų8453.9 Ų53.952%0.51529%0.289SS..Hα-helixtrans-62.8-32179.7-55.70000112.8E546 K547 V548E546-T550 PolarHBondContact O-N 2.97Å; E546-T550 VanDerWaalsContact O-N 3.13Å; E546-T550 PolarHBondContact O-OG1 3.01Å; K547-T550 WeakPolarHBondContact O-CB 3.18Å; K547-T550 PolarHBondContact O-N 3.1Å; K547-T550 VanDerWaalsContact O-N 3.11Å; V548-T550 VanDerWaalsContact C-N 3.29Å; V548-T550 PolarHBondContact O-N 3.07Å
551Y73Confident83.6Confident57 Ų5753.8 Ų53.822%0.22429%0.288CS..THydrogen-bonded Turntrans-108.511.1-176.5-56.3-87.5000113.6L320 D324 K547 V548 A549 D553 K554 V555 M557L320-Y551 HydrophobicContact CD2-CE1 3.63Å; L320-Y551 HydrophobicContact CD2-CE2 3.97Å; L320-Y551 WeakPolarHBondContact CD2-OH 3.45Å; D324-Y551 PolarHBondContact OD2-OH 3.47Å; K547-Y551 WeakPolarHBondContact O-CD2 3.42Å; K547-Y551 PolarHBondContact O-N 2.62Å; V548-Y551 PolarHBondContact O-N 2.88Å; A549-Y551 VanDerWaalsContact C-N 3.27Å; A549-Y551 PolarHBondContact O-N 2.76Å; Y551-D553 VanDerWaalsContact C-N 3.34Å; Y551-D553 PolarHBondContact O-N 3.04Å; Y551-K554 WeakPolarHBondContact O-CB 3.41Å; Y551-K554 VanDerWaalsContact O-CG 3.25Å; Y551-K554 WeakPolarHBondContact O-CG 3.26Å; Y551-K554 PolarHBondContact O-N 3.16Å; Y551-V555 HydrophobicContact CG-CG2 4.39Å; Y551-M557 HydrophobicContact CD2-CE 3.24Å; Y551-M557 HydrophobicContact CE2-CE 3.84Å; Y551-M557 HydrophobicContact CG-CE 4.04Å
552D66.4Low83.7Confident119 Ų11952.7 Ų52.764%0.63628%0.283SS*.THydrogen-bonded Turntrans4751.3169.6-167.138.9000113.2V548 A549 K554V548-D552 PolarHBondContact O-N 3.23Å; A549-D552 PolarHBondContact O-N 2.76Å; D552-K554 PolarHBondContact O-N 2.95Å
553D67.7Low83.8Confident137 Ų13749.4 Ų49.473%0.73326%0.26SS*.THydrogen-bonded Turntrans59.44.9-177.7-64.6-33.9000116.8Y551 V555Y551-D553 VanDerWaalsContact C-N 3.34Å; Y551-D553 PolarHBondContact O-N 3.04Å; D553-V555 PolarHBondContact O-N 3.4Å
554K69.5Low84.1Confident135 Ų13547.1 Ų47.159%0.58725%0.248SC*.  trans-66.7-24.9179.1-62.3172-173.11720113Y551 D552Y551-K554 WeakPolarHBondContact O-CB 3.41Å; Y551-K554 VanDerWaalsContact O-CG 3.25Å; Y551-K554 WeakPolarHBondContact O-CG 3.26Å; Y551-K554 PolarHBondContact O-N 3.16Å; D552-K554 PolarHBondContact O-N 2.95Å
555V73.9Confident84.5Confident9 Ų946.1 Ų46.16%0.05524%0.244CC..SBendtrans-117.6115.4-176.8-176.70000109.9Q316 V317 L320 Y551 D553 M557 W559Q316-V555 HydrophobicContact CB-CG2 4.42Å; V317-V555 HydrophobicContact CG2-CG1 3.87Å; L320-V555 HydrophobicContact CD1-CG1 3.97Å; L320-V555 HydrophobicContact CD1-CG2 4.17Å; Y551-V555 HydrophobicContact CG-CG2 4.39Å; D553-V555 PolarHBondContact O-N 3.4Å; V555-M557 HydrophobicContact CB-CE 4.32Å; V555-M557 HydrophobicContact CB-CG 4.41Å; V555-M557 HydrophobicContact CG1-CE 4.49Å; V555-M557 HydrophobicContact CG1-CG 4.09Å; V555-M557 WeakPolarHBondContact O-CG 2.83Å; V555-M557 PolarHBondContact O-N 3Å; V555-W559 HydrophobicContact CG1-CZ2 4.37Å
556Y84.4Confident84.9Confident75 Ų7543.5 Ų43.529%0.29423%0.225SC..  trans-73.4101.1172.5-176.5-148.3000111V512 F558 W559V512-Y556 WeakPolarHBondContact CA-OH 3.32Å; Y556-F558 VanDerWaalsContact C-N 3.33Å; Y556-F558 AromaticContact CD1-CD1 3.36Å; Y556-F558 HydrophobicContact CD1-CD1 3.36Å; Y556-F558 AromaticContact CD1-CE1 3.83Å; Y556-F558 HydrophobicContact CD1-CE1 3.83Å; Y556-F558 HydrophobicContact CD1-CG 4.42Å; Y556-F558 HydrophobicContact CD2-CD1 4.36Å; Y556-F558 HydrophobicContact CE1-CB 4.26Å; Y556-F558 AromaticContact CE1-CD1 3.38Å; Y556-F558 HydrophobicContact CE1-CD1 3.38Å; Y556-F558 HydrophobicContact CE1-CE1 4.03Å; Y556-F558 HydrophobicContact CE1-CG 4.09Å; Y556-F558 HydrophobicContact CE2-CB 4.08Å; Y556-F558 HydrophobicContact CE2-CD1 4.37Å; Y556-F558 AromaticContact CG-CD1 3.87Å; Y556-F558 HydrophobicContact CG-CD1 3.87Å; Y556-F558 AromaticContact CZ-CD1 3.91Å; Y556-F558 PolarHBondContact O-N 2.92Å; Y556-W559 PolarHBondContact O-NE1 2.68Å
557M87Confident85.2Confident6 Ų638.5 Ų38.53%0.0320%0.202CC..G310 helixtrans-86.723-167.5-64.7-160.217800115.9F544 K547 V548 Y551 V555 W559 L560F544-M557 HydrophobicContact CE2-CB 3.96Å; F544-M557 HydrophobicContact CZ-CB 4.18Å; K547-M557 HydrophobicContact CB-CE 4.41Å; K547-M557 HydrophobicContact CB-SD 4.25Å; K547-M557 WeakPolarHBondContact O-CE 3.49Å; V548-M557 HydrophobicContact CG2-CB 4.39Å; V548-M557 HydrophobicContact CG2-CG 4.33Å; V548-M557 HydrophobicContact CG2-SD 3.87Å; Y551-M557 HydrophobicContact CD2-CE 3.24Å; Y551-M557 HydrophobicContact CE2-CE 3.84Å; Y551-M557 HydrophobicContact CG-CE 4.04Å; V555-M557 HydrophobicContact CB-CE 4.32Å; V555-M557 HydrophobicContact CB-CG 4.41Å; V555-M557 HydrophobicContact CG1-CE 4.49Å; V555-M557 HydrophobicContact CG1-CG 4.09Å; V555-M557 WeakPolarHBondContact O-CG 2.83Å; V555-M557 PolarHBondContact O-N 3Å; M557-W559 PolarHBondContact O-N 3.49Å; M557-L560 WeakPolarHBondContact O-CB 3.29Å; M557-L560 PolarHBondContact O-N 2.91Å; M557-L560 VanDerWaalsContact O-N 3.1Å; M557-L560 HydrophobicContact SD-CD2 4.35Å
558F90.1Very high86Confident7 Ų735.9 Ų35.93%0.03119%0.191CC..G310 helixtrans-56.2-26.9178.374.7-89.1000113.2S508 F511 V512 Y556 L560 P561 I598S508-F558 WeakPolarHBondContact CB-O 3.31Å; S508-F558 PolarHBondContact OG-O 3.45Å; F511-F558 HydrophobicContact CB-CB 4.11Å; V512-F558 HydrophobicContact CG2-CB 3.74Å; V512-F558 HydrophobicContact CG2-CD1 4.41Å; V512-F558 HydrophobicContact CG2-CD2 3.64Å; V512-F558 HydrophobicContact CG2-CE2 4.4Å; V512-F558 HydrophobicContact CG2-CG 3.66Å; Y556-F558 VanDerWaalsContact C-N 3.33Å; Y556-F558 AromaticContact CD1-CD1 3.36Å; Y556-F558 HydrophobicContact CD1-CD1 3.36Å; Y556-F558 AromaticContact CD1-CE1 3.83Å; Y556-F558 HydrophobicContact CD1-CE1 3.83Å; Y556-F558 HydrophobicContact CD1-CG 4.42Å; Y556-F558 HydrophobicContact CD2-CD1 4.36Å; Y556-F558 HydrophobicContact CE1-CB 4.26Å; Y556-F558 AromaticContact CE1-CD1 3.38Å; Y556-F558 HydrophobicContact CE1-CD1 3.38Å; Y556-F558 HydrophobicContact CE1-CE1 4.03Å; Y556-F558 HydrophobicContact CE1-CG 4.09Å; Y556-F558 HydrophobicContact CE2-CB 4.08Å; Y556-F558 HydrophobicContact CE2-CD1 4.37Å; Y556-F558 AromaticContact CG-CD1 3.87Å; Y556-F558 HydrophobicContact CG-CD1 3.87Å; Y556-F558 AromaticContact CZ-CD1 3.91Å; Y556-F558 PolarHBondContact O-N 2.92Å; F558-L560 VanDerWaalsContact C-N 3.35Å; F558-P561 WeakPolarHBondContact O-CD 3.39Å; F558-I598 HydrophobicContact CD2-CD1 3.66Å; F558-I598 HydrophobicContact CD2-CG1 4.09Å; F558-I598 HydrophobicContact CE2-CD1 3.79Å; F558-I598 HydrophobicContact CE2-CG1 3.79Å
559W90.3Very high86.9Confident0 Ų034.2 Ų34.20%018%0.181CC..G310 helixtrans-76.7-16.2-176.957.4-95.8000114V317 L320 M321 Y325 V555 Y556 M557 L562 Q563V317-W559 HydrophobicContact CG1-CZ2 4.21Å; L320-W559 HydrophobicContact CB-CH2 3.93Å; L320-W559 HydrophobicContact CB-CZ2 4.26Å; L320-W559 HydrophobicContact CD1-CH2 4.38Å; L320-W559 HydrophobicContact CD1-CZ2 3.97Å; M321-W559 HydrophobicContact CE-CB 4.14Å; M321-W559 HydrophobicContact CE-CD2 3.41Å; M321-W559 VanDerWaalsContact CE-CD2 3.41Å; M321-W559 HydrophobicContact CE-CE3 3.2Å; M321-W559 HydrophobicContact CE-CG 3.83Å; M321-W559 HydrophobicContact CE-CH2 4.43Å; M321-W559 HydrophobicContact CE-CZ3 3.77Å; M321-W559 HydrophobicContact CG-CE3 4.13Å; M321-W559 HydrophobicContact CG-CH2 4.01Å; M321-W559 HydrophobicContact CG-CZ3 3.68Å; Y325-W559 AromaticContact CD2-CH2 3.7Å; Y325-W559 HydrophobicContact CD2-CH2 3.7Å; Y325-W559 HydrophobicContact CD2-CZ3 4.09Å; Y325-W559 AromaticContact CE2-CH2 3.75Å; Y325-W559 HydrophobicContact CE2-CH2 3.75Å; Y325-W559 HydrophobicContact CE2-CZ3 4.42Å; V555-W559 HydrophobicContact CG1-CZ2 4.37Å; Y556-W559 PolarHBondContact O-NE1 2.68Å; M557-W559 PolarHBondContact O-N 3.49Å; W559-L562 WeakPolarHBondContact O-CB 3.45Å; W559-L562 PolarHBondContact O-N 3.48Å; W559-Q563 HydrophobicContact CE3-CB 4.1Å; W559-Q563 HydrophobicContact CZ3-CB 4.09Å; W559-Q563 HydrophobicContact CZ3-CG 4.42Å; W559-Q563 PolarHBondContact O-N 3.25Å; W559-Q563 VanDerWaalsContact O-N 3.1Å
560L92.4Very high87.4Confident0 Ų031.7 Ų31.70%016%0.157CC..Hα-helixtrans-60.2-44.2-171.7179.657.2000113.4Y325 F544 M557 F558 L562 Q563 W564Y325-L560 HydrophobicContact CD1-CD1 3.61Å; Y325-L560 HydrophobicContact CD2-CD1 4.28Å; Y325-L560 HydrophobicContact CE1-CD1 3.43Å; Y325-L560 VanDerWaalsContact CE1-CD1 3.43Å; Y325-L560 HydrophobicContact CE1-CD2 4.2Å; Y325-L560 HydrophobicContact CE1-CG 4.48Å; Y325-L560 HydrophobicContact CE2-CD1 4.14Å; Y325-L560 HydrophobicContact CG-CD1 4.03Å; F544-L560 HydrophobicContact CD2-CD2 3.91Å; F544-L560 HydrophobicContact CE2-CD2 4.43Å; M557-L560 WeakPolarHBondContact O-CB 3.29Å; M557-L560 PolarHBondContact O-N 2.91Å; M557-L560 VanDerWaalsContact O-N 3.1Å; M557-L560 HydrophobicContact SD-CD2 4.35Å; F558-L560 VanDerWaalsContact C-N 3.35Å; L560-L562 PolarHBondContact O-N 2.58Å; L560-Q563 WeakPolarHBondContact O-CB 3.32Å; L560-Q563 PolarHBondContact O-N 2.78Å; L560-Q563 VanDerWaalsContact O-N 3.07Å; L560-W564 HydrophobicContact CD1-CZ2 4.28Å; L560-W564 HydrophobicContact CD2-CH2 4.37Å; L560-W564 HydrophobicContact CD2-CZ2 3.68Å; L560-W564 HydrophobicContact CG-CD2 4.35Å; L560-W564 HydrophobicContact CG-CH2 4.36Å; L560-W564 HydrophobicContact CG-CZ2 3.66Å; L560-W564 PolarHBondContact O-N 3Å
561P96Very high88Confident0 Ų031.8 Ų31.80%015%0.151CC..Hα-helixtrans-60.7-30.9174-23.133.5000114Y504 L507 F511 F558 W564 A565Y504-P561 WeakPolarHBondContact CB-O 3.16Å; Y504-P561 HydrophobicContact CG-CB 4.45Å; L507-P561 HydrophobicContact CD2-CB 4.06Å; L507-P561 HydrophobicContact CD2-CG 3.82Å; L507-P561 HydrophobicContact CG-CB 4.34Å; L507-P561 HydrophobicContact CG-CG 3.98Å; F511-P561 HydrophobicContact CD2-CG 4.1Å; F511-P561 HydrophobicContact CE2-CG 3.58Å; F558-P561 WeakPolarHBondContact O-CD 3.39Å; P561-W564 HydrophobicContact CB-CE3 4.13Å; P561-W564 HydrophobicContact CG-CE3 4.39Å; P561-W564 HydrophobicContact CG-CZ3 4.33Å; P561-W564 WeakPolarHBondContact O-CB 3.37Å; P561-W564 PolarHBondContact O-N 2.97Å; P561-A565 WeakPolarHBondContact O-CB 3.43Å; P561-A565 PolarHBondContact O-N 3.42Å
562L96.4Very high89.1Confident1 Ų129 Ų291%0.00514%0.14CC..Hα-helixtrans-72.5-35175.2-61.1178.6000111.5I505 S508 W559 L560 W564 A565 C566 I591 R595 I598I505-L562 HydrophobicContact CG1-CD2 4.13Å; S508-L562 WeakPolarHBondContact OG-CD1 3.47Å; S508-L562 WeakPolarHBondContact OG-CG 3.36Å; W559-L562 WeakPolarHBondContact O-CB 3.45Å; W559-L562 PolarHBondContact O-N 3.48Å; L560-L562 PolarHBondContact O-N 2.58Å; L562-W564 VanDerWaalsContact C-N 3.33Å; L562-A565 WeakPolarHBondContact O-CB 3.44Å; L562-A565 PolarHBondContact O-N 3.29Å; L562-C566 PolarHBondContact O-N 2.88Å; L562-C566 PolarHBondContact O-SG 2.98Å; L562-I591 HydrophobicContact CB-CG2 4.22Å; L562-I591 HydrophobicContact CD2-CG2 4.11Å; L562-R595 HydrophobicContact CD1-CB 3.52Å; L562-R595 HydrophobicContact CD1-CG 3.82Å; L562-I598 HydrophobicContact CD1-CD1 3.53Å; L562-I598 HydrophobicContact CD1-CG1 4.45Å
563Q93.9Very high90.5Very high0 Ų026 Ų260%012%0.121CC..Hα-helixtrans-62.2-42.6170-176.963.862.600110.9W559 L560 A565 C566 N567W559-Q563 HydrophobicContact CE3-CB 4.1Å; W559-Q563 HydrophobicContact CZ3-CB 4.09Å; W559-Q563 HydrophobicContact CZ3-CG 4.42Å; W559-Q563 PolarHBondContact O-N 3.25Å; W559-Q563 VanDerWaalsContact O-N 3.1Å; L560-Q563 WeakPolarHBondContact O-CB 3.32Å; L560-Q563 PolarHBondContact O-N 2.78Å; L560-Q563 VanDerWaalsContact O-N 3.07Å; Q563-A565 VanDerWaalsContact C-N 3.31Å; Q563-A565 PolarHBondContact O-N 2.92Å; Q563-C566 PolarHBondContact O-N 2.89Å; Q563-N567 PolarHBondContact NE2-OD1 3.36Å; Q563-N567 WeakPolarHBondContact O-CB 3.44Å; Q563-N567 VanDerWaalsContact O-CG 3.26Å; Q563-N567 PolarHBondContact O-N 2.92Å
564W96.6Very high91.6Very high4 Ų426.6 Ų26.62%0.01512%0.117CC..Hα-helixtrans-60.6-41172.5-60.8-25000112I329 P330 Y504 E540 I543 F544 L560 P561 L562 N567 L568I329-W564 WeakPolarHBondContact CG2-O 3.42Å; P330-W564 HydrophobicContact CG-CD2 3.59Å; P330-W564 HydrophobicContact CG-CE3 3.8Å; P330-W564 HydrophobicContact CG-CG 4.05Å; P330-W564 HydrophobicContact CG-CH2 4.16Å; P330-W564 HydrophobicContact CG-CZ2 3.97Å; P330-W564 HydrophobicContact CG-CZ3 4.09Å; Y504-W564 HydrophobicContact CD1-CE3 4.41Å; Y504-W564 HydrophobicContact CD2-CB 3.81Å; Y504-W564 HydrophobicContact CE1-CE3 4.01Å; Y504-W564 HydrophobicContact CE2-CB 3.56Å; Y504-W564 HydrophobicContact CE2-CE3 4.44Å; E540-W564 HydrophobicContact CB-CH2 4.48Å; E540-W564 HydrophobicContact CB-CZ3 4.26Å; I543-W564 HydrophobicContact CG2-CZ2 4Å; F544-W564 HydrophobicContact CB-CH2 4.18Å; F544-W564 HydrophobicContact CD2-CH2 4.49Å; L560-W564 HydrophobicContact CD1-CZ2 4.28Å; L560-W564 HydrophobicContact CD2-CH2 4.37Å; L560-W564 HydrophobicContact CD2-CZ2 3.68Å; L560-W564 HydrophobicContact CG-CD2 4.35Å; L560-W564 HydrophobicContact CG-CH2 4.36Å; L560-W564 HydrophobicContact CG-CZ2 3.66Å; L560-W564 PolarHBondContact O-N 3Å; P561-W564 HydrophobicContact CB-CE3 4.13Å; P561-W564 HydrophobicContact CG-CE3 4.39Å; P561-W564 HydrophobicContact CG-CZ3 4.33Å; P561-W564 WeakPolarHBondContact O-CB 3.37Å; P561-W564 PolarHBondContact O-N 2.97Å; L562-W564 VanDerWaalsContact C-N 3.33Å; W564-N567 PolarHBondContact O-N 3Å; W564-L568 VanDerWaalsContact O-CB 3.26Å; W564-L568 WeakPolarHBondContact O-CB 3.37Å; W564-L568 PolarHBondContact O-N 3.37Å
565A97.7Very high92.8Very high0 Ų023.3 Ų23.30%010%0.104CC..Hα-helixtrans-61.4-46.8175.600000111.3L501 Y504 P561 L562 Q563 N567 L568 V569 I591L501-A565 HydrophobicContact CD2-CB 3.98Å; L501-A565 WeakPolarHBondContact CD2-O 3.41Å; Y504-A565 HydrophobicContact CD2-CB 4.14Å; P561-A565 WeakPolarHBondContact O-CB 3.43Å; P561-A565 PolarHBondContact O-N 3.42Å; L562-A565 WeakPolarHBondContact O-CB 3.44Å; L562-A565 PolarHBondContact O-N 3.29Å; Q563-A565 VanDerWaalsContact C-N 3.31Å; Q563-A565 PolarHBondContact O-N 2.92Å; A565-N567 PolarHBondContact O-N 2.86Å; A565-L568 WeakPolarHBondContact O-CB 3.46Å; A565-L568 PolarHBondContact O-N 2.92Å; A565-V569 WeakPolarHBondContact O-CG2 3.25Å; A565-V569 PolarHBondContact O-N 3.27Å; A565-I591 HydrophobicContact CB-CD1 4.1Å; A565-I591 HydrophobicContact CB-CG2 4.36Å
566C96.7Very high93.8Very high0 Ų030.9 Ų30.90%014%0.139CC..Hα-helixtrans-59.3-47.3176.2-67.10000111.9I108 I112 L562 Q563 L568 V569 T570 M588I108-C566 HydrophobicContact CG2-CB 3.85Å; I108-C566 WeakPolarHBondContact CG2-SG 3.46Å; I112-C566 HydrophobicContact CG2-CB 4.17Å; L562-C566 PolarHBondContact O-N 2.88Å; L562-C566 PolarHBondContact O-SG 2.98Å; Q563-C566 PolarHBondContact O-N 2.89Å; C566-L568 VanDerWaalsContact C-N 3.28Å; C566-L568 PolarHBondContact O-N 2.89Å; C566-V569 PolarHBondContact O-N 3.13Å; C566-T570 PolarHBondContact O-N 3.47Å; C566-T570 PolarHBondContact O-OG1 2.74Å; C566-M588 HydrophobicContact CB-CE 4.04Å; C566-M588 HydrophobicContact CB-SD 3.7Å; C566-M588 PolarHBondContact SG-SD 2.79Å
567N95.5Very high94.3Very high9 Ų929.2 Ų29.25%0.04813%0.132CC..Hα-helixtrans-63.3-35.5177.4-67.5-14000111.7Y325 K328 I329 Q563 W564 A565 T570 K571Y325-N567 PolarHBondContact O-ND2 2.77Å; K328-N567 PolarHBondContact N-ND2 3.03Å; K328-N567 PolarHBondContact O-ND2 3.18Å; I329-N567 HydrophobicContact CG2-CB 3.33Å; Q563-N567 PolarHBondContact NE2-OD1 3.36Å; Q563-N567 WeakPolarHBondContact O-CB 3.44Å; Q563-N567 VanDerWaalsContact O-CG 3.26Å; Q563-N567 PolarHBondContact O-N 2.92Å; W564-N567 PolarHBondContact O-N 3Å; A565-N567 PolarHBondContact O-N 2.86Å; N567-T570 PolarHBondContact O-N 2.92Å; N567-K571 PolarHBondContact O-N 3.41Å
568L97.2Very high94.7Very high1 Ų129 Ų291%0.00513%0.131CC..Hα-helixtrans-67.9-38.4175.4179.957.8000112.1I329 L332 I497 T500 L501 W564 A565 C566 K571 A572I329-L568 HydrophobicContact CD1-CD1 4.15Å; I329-L568 HydrophobicContact CG2-CB 4.35Å; L332-L568 HydrophobicContact CD1-CD1 3.65Å; L332-L568 HydrophobicContact CD2-CD1 3.98Å; L332-L568 HydrophobicContact CD2-CD2 4.01Å; L332-L568 HydrophobicContact CG-CD1 4.37Å; I497-L568 HydrophobicContact CG1-CD1 4.32Å; I497-L568 HydrophobicContact CG2-CD1 4.37Å; I497-L568 HydrophobicContact CG2-CD2 4.45Å; I497-L568 HydrophobicContact CG2-CG 4.2Å; T500-L568 HydrophobicContact CG2-CD2 3.67Å; L501-L568 HydrophobicContact CD2-CB 4.05Å; L501-L568 HydrophobicContact CD2-CD2 3.86Å; L501-L568 HydrophobicContact CD2-CG 4.01Å; L501-L568 HydrophobicContact CG-CD2 3.91Å; L501-L568 HydrophobicContact CG-CG 4.32Å; W564-L568 VanDerWaalsContact O-CB 3.26Å; W564-L568 WeakPolarHBondContact O-CB 3.37Å; W564-L568 PolarHBondContact O-N 3.37Å; A565-L568 WeakPolarHBondContact O-CB 3.46Å; A565-L568 PolarHBondContact O-N 2.92Å; C566-L568 VanDerWaalsContact C-N 3.28Å; C566-L568 PolarHBondContact O-N 2.89Å; L568-K571 PolarHBondContact O-N 3.34Å; L568-A572 WeakPolarHBondContact O-CB 3.48Å; L568-A572 PolarHBondContact O-N 2.93Å
569V97.2Very high94.8Very high0 Ų034 Ų340%015%0.154CC..Hα-helixtrans-63.4-43.2172.5178.20000110.5L501 A565 C566 K571 A572 K573 I578 Y584 V587 M588 I591L501-V569 HydrophobicContact CD1-CG2 4.03Å; L501-V569 HydrophobicContact CD2-CG2 3.6Å; L501-V569 HydrophobicContact CG-CG2 4.5Å; A565-V569 WeakPolarHBondContact O-CG2 3.25Å; A565-V569 PolarHBondContact O-N 3.27Å; C566-V569 PolarHBondContact O-N 3.13Å; V569-K571 VanDerWaalsContact C-N 3.31Å; V569-K571 PolarHBondContact O-N 3.22Å; V569-A572 PolarHBondContact O-N 3.24Å; V569-K573 PolarHBondContact O-N 3.35Å; V569-I578 HydrophobicContact CG1-CD1 3.73Å; V569-Y584 HydrophobicContact CB-CE2 4.47Å; V569-Y584 HydrophobicContact CG1-CD2 3.6Å; V569-Y584 HydrophobicContact CG1-CE2 3.69Å; V569-V587 HydrophobicContact CG1-CB 4.19Å; V569-V587 HydrophobicContact CG1-CG1 4.03Å; V569-V587 HydrophobicContact CG2-CG1 3.64Å; V569-M588 HydrophobicContact CB-CE 4.07Å; V569-M588 HydrophobicContact CG1-CE 4.12Å; V569-I591 HydrophobicContact CG2-CD1 3.71Å
570T93.2Very high94.8Very high21 Ų2136 Ų3613%0.12917%0.169CC..Hα-helixtrans-60.9-41.1174.8-54.20000111.4C566 N567 K573 K574 Y584C566-T570 PolarHBondContact O-N 3.47Å; C566-T570 PolarHBondContact O-OG1 2.74Å; N567-T570 PolarHBondContact O-N 2.92Å; T570-K573 PolarHBondContact O-N 3Å; T570-K574 WeakPolarHBondContact O-CG 3.46Å; T570-K574 PolarHBondContact O-N 2.91Å; T570-K574 VanDerWaalsContact O-N 3.12Å; T570-Y584 PolarHBondContact OG1-OH 2.73Å
571K93.9Very high94.7Very high86 Ų8638.6 Ų38.637%0.37418%0.182SC..Hα-helixtrans-64.4-43.4174.6-170.4174.9-177169.30112I329 N567 L568 V569 K573 K574 E575I329-K571 HydrophobicContact CD1-CD 3.38Å; N567-K571 PolarHBondContact O-N 3.41Å; L568-K571 PolarHBondContact O-N 3.34Å; V569-K571 VanDerWaalsContact C-N 3.31Å; V569-K571 PolarHBondContact O-N 3.22Å; K571-K573 VanDerWaalsContact C-N 3.28Å; K571-K573 PolarHBondContact O-N 3.43Å; K571-K574 PolarHBondContact O-N 3.15Å; K571-K574 VanDerWaalsContact O-N 3.13Å; K571-E575 WeakPolarHBondContact CE-OE1 3.45Å; K571-E575 WeakPolarHBondContact CG-OE1 3.46Å; K571-E575 WeakPolarHBondContact O-CG 3.48Å; K571-E575 PolarHBondContact O-N 2.87Å
572A96.1Very high94.4Very high0 Ų043.4 Ų43.40%021%0.207CC..Hα-helixtrans-61.4-36176.400000112.4I487 I497 L568 V569 E575 E576 R577 I578I487-A572 HydrophobicContact CD1-CB 4.39Å; I497-A572 HydrophobicContact CD1-CB 4.3Å; I497-A572 HydrophobicContact CG2-CB 4.07Å; L568-A572 WeakPolarHBondContact O-CB 3.48Å; L568-A572 PolarHBondContact O-N 2.93Å; V569-A572 PolarHBondContact O-N 3.24Å; A572-E575 CarbonylContact O-C 2.79Å; A572-E575 PolarHBondContact O-N 3.27Å; A572-E576 PolarHBondContact O-N 3.09Å; A572-R577 HydrophobicContact CB-CB 4.41Å; A572-R577 WeakPolarHBondContact O-CB 3.35Å; A572-R577 PolarHBondContact O-N 3.37Å; A572-I578 HydrophobicContact CB-CD1 4.18Å; A572-I578 HydrophobicContact CB-CG1 4.34Å
573K94.2Very high94.3Very high54 Ų5444.7 Ų44.724%0.23521%0.214CC..Hα-helixtrans-64.4-42.9172.8179.957.4-178.8164.10111.9V569 T570 K571 E575 E576 I578 E579 D581 Y584V569-K573 PolarHBondContact O-N 3.35Å; T570-K573 PolarHBondContact O-N 3Å; K571-K573 VanDerWaalsContact C-N 3.28Å; K571-K573 PolarHBondContact O-N 3.43Å; K573-E575 VanDerWaalsContact C-N 3.31Å; K573-E575 PolarHBondContact O-N 3.49Å; K573-E576 PolarHBondContact O-N 3.42Å; K573-E576 VanDerWaalsContact O-N 3.07Å; K573-I578 HydrophobicContact CB-CB 4.4Å; K573-I578 HydrophobicContact CB-CD1 4.3Å; K573-I578 HydrophobicContact CD-CB 3.93Å; K573-I578 HydrophobicContact CD-CG2 4.29Å; K573-I578 VanDerWaalsContact CD-O 3.22Å; K573-I578 WeakPolarHBondContact CD-O 3.33Å; K573-I578 PolarHBondContact NZ-O 3.17Å; K573-E579 PolarHBondContact NZ-O 3.15Å; K573-D581 WeakPolarHBondContact CE-OD1 3.44Å; K573-D581 IonicContact NZ-OD1 2.73Å; K573-Y584 HydrophobicContact CB-CD2 3.9Å; K573-Y584 HydrophobicContact CB-CE2 4.3Å; K573-Y584 HydrophobicContact CG-CD2 4.27Å; K573-Y584 HydrophobicContact CG-CG 4.45Å
574K91.4Very high94.3Very high151 Ų15145 Ų4566%0.65722%0.215SC*.Hα-helixtrans-66.6-31175.6-68.7-179.9179.8-175.20113T570 K571 E576T570-K574 WeakPolarHBondContact O-CG 3.46Å; T570-K574 PolarHBondContact O-N 2.91Å; T570-K574 VanDerWaalsContact O-N 3.12Å; K571-K574 PolarHBondContact O-N 3.15Å; K571-K574 VanDerWaalsContact O-N 3.13Å; K574-E576 PolarHBondContact O-N 3.01Å
575E94.5Very high93.9Very high65 Ų6546.6 Ų46.630%0.30422%0.222SC..THydrogen-bonded Turntrans-78.910.6171.6-67.6177-157.900112.7R493 K571 A572 K573 R577R493-E575 IonicContact CZ-OE1 2.82Å; R493-E575 IonicContact CZ-OE2 3.49Å; R493-E575 IonicContact NE-OE1 2.75Å; R493-E575 IonicContact NE-OE2 3.16Å; R493-E575 PolarHBondContact NE-OE2 3.01Å; R493-E575 VanDerWaalsContact NE-OE2 3.09Å; R493-E575 IonicContact NH2-OE1 3.51Å; R493-E575 PolarHBondContact NH2-OE1 3.39Å; R493-E575 IonicContact NH2-OE2 3.68Å; K571-E575 WeakPolarHBondContact CE-OE1 3.45Å; K571-E575 WeakPolarHBondContact CG-OE1 3.46Å; K571-E575 WeakPolarHBondContact O-CG 3.48Å; K571-E575 PolarHBondContact O-N 2.87Å; A572-E575 CarbonylContact O-C 2.79Å; A572-E575 PolarHBondContact O-N 3.27Å; K573-E575 VanDerWaalsContact C-N 3.31Å; K573-E575 PolarHBondContact O-N 3.49Å; E575-R577 HydrophobicContact CB-CG 4.22Å; E575-R577 PolarHBondContact O-N 3.22Å; E575-R577 IonicContact OE2-NE 3.33Å
576E94.9Very high93.8Very high168 Ų16848.4 Ų48.479%0.78523%0.233SC*.THydrogen-bonded Turntrans57.520.2-179.3-57.6-176164.900114.7A572 K573 K574 I578A572-E576 PolarHBondContact O-N 3.09Å; K573-E576 PolarHBondContact O-N 3.42Å; K573-E576 VanDerWaalsContact O-N 3.07Å; K574-E576 PolarHBondContact O-N 3.01Å; E576-I578 PolarHBondContact O-N 3Å
577R95.5Very high93.8Very high40 Ų4048.5 Ų48.515%0.15123%0.233CC..  trans-81.9-5.1176.6-63.6-177.9177.9-84.8-5.5113.4K488 D491 A572 E575K488-R577 WeakPolarHBondContact CB-O 3.4Å; K488-R577 PolarHBondContact N-O 3.3Å; K488-R577 PolarHBondContact O-NH1 2.81Å; D491-R577 IonicContact OD1-CZ 2.79Å; D491-R577 IonicContact OD1-NH1 2.86Å; D491-R577 PolarHBondContact OD1-NH1 3.39Å; D491-R577 IonicContact OD1-NH2 3.9Å; D491-R577 IonicContact OD2-CZ 3.31Å; D491-R577 IonicContact OD2-NH1 3.74Å; D491-R577 PolarHBondContact OD2-NH1 3.14Å; D491-R577 IonicContact OD2-NH2 3Å; D491-R577 PolarHBondContact OD2-NH2 3.2Å; A572-R577 HydrophobicContact CB-CB 4.41Å; A572-R577 WeakPolarHBondContact O-CB 3.35Å; A572-R577 PolarHBondContact O-N 3.37Å; E575-R577 HydrophobicContact CB-CG 4.22Å; E575-R577 PolarHBondContact O-N 3.22Å; E575-R577 IonicContact OE2-NE 3.33Å
578I95.9Very high93.7Very high1 Ų148.1 Ų48.11%0.00523%0.231CC..SBendtrans-126116.9173.9-54.4179.5000107.2I487 V569 A572 K573 E576 Q583 Y584I487-I578 HydrophobicContact CD1-CD1 3.51Å; I487-I578 HydrophobicContact CD1-CG1 3.61Å; V569-I578 HydrophobicContact CG1-CD1 3.73Å; A572-I578 HydrophobicContact CB-CD1 4.18Å; A572-I578 HydrophobicContact CB-CG1 4.34Å; K573-I578 HydrophobicContact CB-CB 4.4Å; K573-I578 HydrophobicContact CB-CD1 4.3Å; K573-I578 HydrophobicContact CD-CB 3.93Å; K573-I578 HydrophobicContact CD-CG2 4.29Å; K573-I578 VanDerWaalsContact CD-O 3.22Å; K573-I578 WeakPolarHBondContact CD-O 3.33Å; K573-I578 PolarHBondContact NZ-O 3.17Å; E576-I578 PolarHBondContact O-N 3Å; I578-Q583 HydrophobicContact CG2-CB 3.67Å; I578-Y584 HydrophobicContact CD1-CD2 4.21Å
579E91Very high93.5Very high112 Ų11250.1 Ų50.152%0.52324%0.242SC..  trans-70.3-47.2-168.6-58.6173.3122.500111.8K488 K573 Q583K488-E579 HydrophobicContact CD-CG 3.97Å; K488-E579 VanDerWaalsContact CE-CG 3.45Å; K488-E579 WeakPolarHBondContact CE-OE1 3.43Å; K488-E579 IonicContact NZ-OE1 2.52Å; K488-E579 PolarHBondContact NZ-OE1 2.74Å; K488-E579 IonicContact NZ-OE2 3.91Å; K573-E579 PolarHBondContact NZ-O 3.15Å; E579-Q583 PolarHBondContact OE2-NE2 2.87Å
580S91.3Very high93.4Very high44 Ų4450.6 Ų50.631%0.30824%0.244SC..  trans-123.1155.1-170.768.70000113.2L582 Q583 Y584S580-L582 PolarHBondContact O-N 2.84Å; S580-Q583 PolarHBondContact O-N 2.97Å; S580-Q583 WeakPolarHBondContact OG-CG 3.22Å; S580-Q583 PolarHBondContact OG-N 2.89Å; S580-Y584 PolarHBondContact O-N 2.91Å
581D89.8Confident93.6Very high53 Ų5349.7 Ų49.728%0.28324%0.239SC..Hα-helixtrans-61.9-28.4174.2-72.94.5000112S206 L208 K573 K585S206-D581 VanDerWaalsContact CB-OD2 3.24Å; S206-D581 WeakPolarHBondContact CB-OD2 3.4Å; S206-D581 PolarHBondContact OG-OD2 3.08Å; L208-D581 HydrophobicContact CD2-CB 4.1Å; K573-D581 WeakPolarHBondContact CE-OD1 3.44Å; K573-D581 IonicContact NZ-OD1 2.73Å; D581-K585 WeakPolarHBondContact O-CB 3.48Å; D581-K585 PolarHBondContact O-N 3.35Å
582L90.4Very high93.6Very high101 Ų10145.9 Ų45.953%0.52922%0.222SC..Hα-helixtrans-66.4-44175-177.961.9000111.7S580 K585 T586S580-L582 PolarHBondContact O-N 2.84Å; L582-K585 HydrophobicContact CD1-CD 4.5Å; L582-T586 WeakPolarHBondContact O-CB 3.14Å; L582-T586 PolarHBondContact O-N 3.46Å; L582-T586 PolarHBondContact O-OG1 3.09Å
583Q94.3Very high93.5Very high29 Ų2947.9 Ų47.914%0.13624%0.239CC..Hα-helixtrans-63.4-49.5175.3-71169.7-3.900110.4Y486 I578 E579 S580 K585 T586 V587Y486-Q583 HydrophobicContact CD1-CB 4.2Å; Y486-Q583 HydrophobicContact CD1-CG 3.64Å; Y486-Q583 HydrophobicContact CD2-CB 4.03Å; Y486-Q583 HydrophobicContact CD2-CG 4.24Å; Y486-Q583 HydrophobicContact CE1-CG 3.87Å; Y486-Q583 HydrophobicContact CE2-CG 4.45Å; Y486-Q583 HydrophobicContact CG-CB 3.87Å; Y486-Q583 HydrophobicContact CG-CG 3.86Å; I578-Q583 HydrophobicContact CG2-CB 3.67Å; E579-Q583 PolarHBondContact OE2-NE2 2.87Å; S580-Q583 PolarHBondContact O-N 2.97Å; S580-Q583 WeakPolarHBondContact OG-CG 3.22Å; S580-Q583 PolarHBondContact OG-N 2.89Å; Q583-K585 VanDerWaalsContact C-N 3.35Å; Q583-K585 PolarHBondContact O-N 2.94Å; Q583-T586 PolarHBondContact O-N 3.3Å; Q583-V587 WeakPolarHBondContact O-CG2 3.37Å; Q583-V587 PolarHBondContact O-N 3.37Å
584Y93.5Very high93.5Very high7 Ų745.6 Ų45.63%0.02723%0.229CC..Hα-helixtrans-52.3-51.7176.1171.2-109.1000111.8M209 V569 T570 K573 I578 S580 T586 V587 M588M209-Y584 HydrophobicContact CE-CD1 4.43Å; M209-Y584 HydrophobicContact CE-CE1 3.63Å; M209-Y584 HydrophobicContact SD-CD1 4.06Å; M209-Y584 HydrophobicContact SD-CE1 3.84Å; V569-Y584 HydrophobicContact CB-CE2 4.47Å; V569-Y584 HydrophobicContact CG1-CD2 3.6Å; V569-Y584 HydrophobicContact CG1-CE2 3.69Å; T570-Y584 PolarHBondContact OG1-OH 2.73Å; K573-Y584 HydrophobicContact CB-CD2 3.9Å; K573-Y584 HydrophobicContact CB-CE2 4.3Å; K573-Y584 HydrophobicContact CG-CD2 4.27Å; K573-Y584 HydrophobicContact CG-CG 4.45Å; I578-Y584 HydrophobicContact CD1-CD2 4.21Å; S580-Y584 PolarHBondContact O-N 2.91Å; Y584-T586 VanDerWaalsContact C-N 3.28Å; Y584-T586 PolarHBondContact O-N 3.14Å; Y584-V587 PolarHBondContact O-N 3.33Å; Y584-M588 HydrophobicContact CE2-CE 3.91Å; Y584-M588 WeakPolarHBondContact O-CB 3.48Å; Y584-M588 PolarHBondContact O-N 2.88Å
585K89Confident93.6Very high37 Ų3739.4 Ų39.416%0.16120%0.201CC..Hα-helixtrans-56.8-40.6175.2166.9-172.6151.3-170.40112.3L208 K212 D581 L582 Q583 M588 N589L208-K585 HydrophobicContact CD1-CD 3.71Å; L208-K585 HydrophobicContact CD2-CB 4.42Å; L208-K585 HydrophobicContact CD2-CD 3.79Å; L208-K585 HydrophobicContact CG-CD 3.84Å; K212-K585 HydrophobicContact CD-CD 4.14Å; K212-K585 HydrophobicContact CD-CG 4.41Å; K212-K585 HydrophobicContact CG-CD 4.16Å; K212-K585 HydrophobicContact CG-CG 4.49Å; D581-K585 WeakPolarHBondContact O-CB 3.48Å; D581-K585 PolarHBondContact O-N 3.35Å; L582-K585 HydrophobicContact CD1-CD 4.5Å; Q583-K585 VanDerWaalsContact C-N 3.35Å; Q583-K585 PolarHBondContact O-N 2.94Å; K585-M588 PolarHBondContact O-N 3.22Å; K585-N589 WeakPolarHBondContact CG-ND2 3.31Å; K585-N589 WeakPolarHBondContact O-CB 3.43Å; K585-N589 PolarHBondContact O-N 2.89Å; K585-N589 PolarHBondContact O-ND2 2.86Å
586T94.1Very high93.5Very high38 Ų3837.4 Ų37.423%0.23320%0.198CC..Hα-helixtrans-69.6-44.6-175.5-58.40000111I482 Y486 L582 Q583 Y584 M588 N589 E590I482-T586 HydrophobicContact CD1-CG2 4.15Å; I482-T586 HydrophobicContact CG2-CG2 4.26Å; Y486-T586 HydrophobicContact CE2-CG2 3.76Å; L582-T586 WeakPolarHBondContact O-CB 3.14Å; L582-T586 PolarHBondContact O-N 3.46Å; L582-T586 PolarHBondContact O-OG1 3.09Å; Q583-T586 PolarHBondContact O-N 3.3Å; Y584-T586 VanDerWaalsContact C-N 3.28Å; Y584-T586 PolarHBondContact O-N 3.14Å; T586-M588 VanDerWaalsContact C-N 3.3Å; T586-M588 PolarHBondContact O-N 3.03Å; T586-N589 PolarHBondContact O-N 3.27Å; T586-E590 PolarHBondContact O-N 3.37Å
587V96.7Very high93.5Very high1 Ų132.4 Ų32.41%0.00618%0.177CC..Hα-helixtrans-57.8-46.3171.7-176.10000110.2I482 V483 Y486 V569 Q583 Y584 E590 I591I482-V587 HydrophobicContact CG2-CB 4.38Å; I482-V587 HydrophobicContact CG2-CG2 3.85Å; V483-V587 HydrophobicContact CG2-CG1 4.11Å; Y486-V587 HydrophobicContact CD2-CG2 3.98Å; V569-V587 HydrophobicContact CG1-CB 4.19Å; V569-V587 HydrophobicContact CG1-CG1 4.03Å; V569-V587 HydrophobicContact CG2-CG1 3.64Å; Q583-V587 WeakPolarHBondContact O-CG2 3.37Å; Q583-V587 PolarHBondContact O-N 3.37Å; Y584-V587 PolarHBondContact O-N 3.33Å; V587-E590 WeakPolarHBondContact O-CB 3.25Å; V587-E590 PolarHBondContact O-N 3.23Å; V587-I591 HydrophobicContact CG1-CD1 4.23Å; V587-I591 PolarHBondContact O-N 2.66Å
588M94Very high93.4Very high2 Ų230.5 Ų30.51%0.0117%0.17CC..Hα-helixtrans-63.6-45.7-177.9-169.464.663.800113.3I112 C566 V569 Y584 K585 T586 E590 I591 L592I112-M588 HydrophobicContact CB-CE 4.41Å; I112-M588 HydrophobicContact CD1-CE 3.61Å; I112-M588 HydrophobicContact CD1-CG 3.32Å; I112-M588 HydrophobicContact CD1-SD 3.48Å; I112-M588 WeakPolarHBondContact CD1-SD 3.35Å; I112-M588 HydrophobicContact CG2-CE 4Å; I112-M588 HydrophobicContact CG2-SD 4.41Å; C566-M588 HydrophobicContact CB-CE 4.04Å; C566-M588 HydrophobicContact CB-SD 3.7Å; C566-M588 PolarHBondContact SG-SD 2.79Å; V569-M588 HydrophobicContact CB-CE 4.07Å; V569-M588 HydrophobicContact CG1-CE 4.12Å; Y584-M588 HydrophobicContact CE2-CE 3.91Å; Y584-M588 WeakPolarHBondContact O-CB 3.48Å; Y584-M588 PolarHBondContact O-N 2.88Å; K585-M588 PolarHBondContact O-N 3.22Å; T586-M588 VanDerWaalsContact C-N 3.3Å; T586-M588 PolarHBondContact O-N 3.03Å; M588-E590 PolarHBondContact O-N 3.5Å; M588-I591 PolarHBondContact O-N 3.42Å; M588-L592 HydrophobicContact CG-CD1 4.17Å; M588-L592 VanDerWaalsContact O-CG 3.31Å; M588-L592 WeakPolarHBondContact O-CG 3.33Å; M588-L592 PolarHBondContact O-N 3.33Å
589N93.3Very high93.2Very high43 Ų4331 Ų3123%0.2318%0.175CC..Hα-helixtrans-60.1-31.2178-72.5-28.2000111.7R109 K585 T586 L592 A593R109-N589 PolarHBondContact NH1-OD1 2.83Å; R109-N589 PolarHBondContact NH2-OD1 3.34Å; K585-N589 WeakPolarHBondContact CG-ND2 3.31Å; K585-N589 WeakPolarHBondContact O-CB 3.43Å; K585-N589 PolarHBondContact O-N 2.89Å; K585-N589 PolarHBondContact O-ND2 2.86Å; T586-N589 PolarHBondContact O-N 3.27Å; N589-L592 PolarHBondContact O-N 2.95Å; N589-A593 WeakPolarHBondContact O-CB 3.41Å; N589-A593 PolarHBondContact O-N 2.65Å
590E94.5Very high93.2Very high10 Ų1029.5 Ų29.55%0.04717%0.167CC..Hα-helixtrans-70.8-45.5179.7-167.256.3-163.300113.1R478 A479 I482 T586 V587 M588 L592 A593 I594R478-E590 IonicContact CZ-OE1 3Å; R478-E590 IonicContact CZ-OE2 2.89Å; R478-E590 IonicContact NE-OE1 3.34Å; R478-E590 PolarHBondContact NE-OE1 3.08Å; R478-E590 IonicContact NE-OE2 3.22Å; R478-E590 IonicContact NH1-OE1 2.66Å; R478-E590 IonicContact NH1-OE2 2.7Å; R478-E590 PolarHBondContact NH1-OE2 2.72Å; R478-E590 IonicContact NH2-OE1 3.58Å; R478-E590 PolarHBondContact NH2-OE1 3.34Å; R478-E590 IonicContact NH2-OE2 3.97Å; R478-E590 PolarHBondContact NH2-OE2 3.46Å; A479-E590 VanDerWaalsContact CA-CG 3.49Å; A479-E590 HydrophobicContact CB-CG 3.47Å; A479-E590 VanDerWaalsContact CB-CG 3.47Å; I482-E590 HydrophobicContact CD1-CB 4.49Å; I482-E590 HydrophobicContact CD1-CG 4.31Å; T586-E590 PolarHBondContact O-N 3.37Å; V587-E590 WeakPolarHBondContact O-CB 3.25Å; V587-E590 PolarHBondContact O-N 3.23Å; M588-E590 PolarHBondContact O-N 3.5Å; E590-L592 VanDerWaalsContact C-N 3.28Å; E590-L592 PolarHBondContact O-N 3.27Å; E590-A593 PolarHBondContact O-N 2.65Å; E590-I594 PolarHBondContact O-N 2.71Å; E590-I594 VanDerWaalsContact O-N 3.08Å
591I96.8Very high93.3Very high2 Ų227.4 Ų27.41%0.0115%0.152CC..Hα-helixtrans-59.7-43.5173.6-63.1169.2000109.9I505 L562 A565 V569 V587 M588 I594 R595I505-I591 HydrophobicContact CD1-CG1 4.2Å; L562-I591 HydrophobicContact CB-CG2 4.22Å; L562-I591 HydrophobicContact CD2-CG2 4.11Å; A565-I591 HydrophobicContact CB-CD1 4.1Å; A565-I591 HydrophobicContact CB-CG2 4.36Å; V569-I591 HydrophobicContact CG2-CD1 3.71Å; V587-I591 HydrophobicContact CG1-CD1 4.23Å; V587-I591 PolarHBondContact O-N 2.66Å; M588-I591 PolarHBondContact O-N 3.42Å; I591-I594 PolarHBondContact O-N 2.87Å; I591-R595 PolarHBondContact O-N 2.95Å
592L94.5Very high93.2Very high6 Ų625.7 Ų25.73%0.03114%0.144CC..Hα-helixtrans-68.5-32.8179.3-68.5178.4000113.6I108 M588 N589 E590 G596I108-L592 HydrophobicContact CB-CD2 3.78Å; I108-L592 HydrophobicContact CD1-CD2 3.69Å; I108-L592 HydrophobicContact CG1-CD2 4.34Å; I108-L592 HydrophobicContact CG2-CD2 3.66Å; M588-L592 HydrophobicContact CG-CD1 4.17Å; M588-L592 VanDerWaalsContact O-CG 3.31Å; M588-L592 WeakPolarHBondContact O-CG 3.33Å; M588-L592 PolarHBondContact O-N 3.33Å; N589-L592 PolarHBondContact O-N 2.95Å; E590-L592 VanDerWaalsContact C-N 3.28Å; E590-L592 PolarHBondContact O-N 3.27Å; L592-G596 PolarHBondContact O-N 2.88Å
593A93.5Very high93Very high41 Ų4121.9 Ų21.934%0.33913%0.125SC..Hα-helixtrans-65.7-45.6173.900000110.9N589 E590 G596 N597N589-A593 WeakPolarHBondContact O-CB 3.41Å; N589-A593 PolarHBondContact O-N 2.65Å; E590-A593 PolarHBondContact O-N 2.65Å; A593-G596 PolarHBondContact O-N 2.8Å; A593-N597 PolarHBondContact O-N 3.28Å
594I95.3Very high92.7Very high6 Ų620.9 Ų20.93%0.03112%0.12CC..Hα-helixtrans-61.7-46.1174.9-67.5164.6000110.7A479 I505 E590 I591 G596 N597 I598A479-I594 HydrophobicContact CB-CD1 3.76Å; I505-I594 HydrophobicContact CD1-CD1 4.31Å; I505-I594 HydrophobicContact CG2-CD1 3.61Å; I505-I594 HydrophobicContact CG2-CG2 4.16Å; E590-I594 PolarHBondContact O-N 2.71Å; E590-I594 VanDerWaalsContact O-N 3.08Å; I591-I594 PolarHBondContact O-N 2.87Å; I594-G596 VanDerWaalsContact C-N 3.25Å; I594-G596 PolarHBondContact O-N 3.46Å; I594-N597 PolarHBondContact O-N 2.78Å; I594-I598 HydrophobicContact CG2-CG2 4.27Å; I594-I598 WeakPolarHBondContact O-CG1 3.16Å; I594-I598 PolarHBondContact O-N 3.13Å
595R94Very high92.4Very high21 Ų2122.3 Ų22.38%0.07913%0.128CC..Hα-helixtrans-51.6-46174.1-172.3-128.554.9120.7-8.9111.8D104 S105 I108 L562 I591 I598 G599D104-R595 IonicContact OD1-NH1 3.56Å; D104-R595 PolarHBondContact OD1-NH1 3.48Å; D104-R595 IonicContact OD2-NH1 3.29Å; D104-R595 PolarHBondContact OD2-NH1 3.11Å; S105-R595 PolarHBondContact OG-NE 3.45Å; S105-R595 PolarHBondContact OG-NH2 3.37Å; I108-R595 HydrophobicContact CD1-CG 4.32Å; L562-R595 HydrophobicContact CD1-CB 3.52Å; L562-R595 HydrophobicContact CD1-CG 3.82Å; I591-R595 PolarHBondContact O-N 2.95Å; R595-I598 VanDerWaalsContact O-CG1 3.32Å; R595-I598 WeakPolarHBondContact O-CG1 3.47Å; R595-G599 PolarHBondContact O-N 3.33Å
596G91.9Very high92.1Very high23 Ų2323.4 Ų23.424%0.23713%0.131CC..Hα-helixtrans-61.2-42.9177.600000112.6L592 A593 I594 K600L592-G596 PolarHBondContact O-N 2.88Å; A593-G596 PolarHBondContact O-N 2.8Å; I594-G596 VanDerWaalsContact C-N 3.25Å; I594-G596 PolarHBondContact O-N 3.46Å; G596-K600 VanDerWaalsContact O-CB 3.3Å; G596-K600 WeakPolarHBondContact O-CB 3.35Å; G596-K600 PolarHBondContact O-N 3.13Å
597N94.6Very high91.7Very high63 Ų6321.7 Ų21.734%0.33712%0.121SC..Hα-helixtrans-67.5-48.2179-75.4-10.9000112.5T472 A593 I594 G599 K600 L601T472-N597 HydrophobicContact CG2-CB 4.39Å; T472-N597 WeakPolarHBondContact CG2-O 3.5Å; A593-N597 PolarHBondContact O-N 3.28Å; I594-N597 PolarHBondContact O-N 2.78Å; N597-G599 VanDerWaalsContact C-N 3.31Å; N597-G599 PolarHBondContact O-N 2.99Å; N597-K600 WeakPolarHBondContact O-CB 3.33Å; N597-K600 PolarHBondContact O-N 3.41Å; N597-L601 PolarHBondContact O-N 2.97Å
598I94.1Very high91.3Very high1 Ų122 Ų221%0.00512%0.123CC..Hα-helixtrans-66.2-34.5178.565.4173.8000112.1S474 S508 T509 V512 F558 L562 I594 R595 L601 S602S474-I598 VanDerWaalsContact OG-CG2 3.24Å; S474-I598 WeakPolarHBondContact OG-CG2 3.14Å; S508-I598 WeakPolarHBondContact OG-CD1 3.43Å; T509-I598 HydrophobicContact CG2-CG2 4.26Å; V512-I598 HydrophobicContact CG2-CB 4.34Å; F558-I598 HydrophobicContact CD2-CD1 3.66Å; F558-I598 HydrophobicContact CD2-CG1 4.09Å; F558-I598 HydrophobicContact CE2-CD1 3.79Å; F558-I598 HydrophobicContact CE2-CG1 3.79Å; L562-I598 HydrophobicContact CD1-CD1 3.53Å; L562-I598 HydrophobicContact CD1-CG1 4.45Å; I594-I598 HydrophobicContact CG2-CG2 4.27Å; I594-I598 WeakPolarHBondContact O-CG1 3.16Å; I594-I598 PolarHBondContact O-N 3.13Å; R595-I598 VanDerWaalsContact O-CG1 3.32Å; R595-I598 WeakPolarHBondContact O-CG1 3.47Å; I598-L601 WeakPolarHBondContact O-CB 3.45Å; I598-L601 PolarHBondContact O-N 3.4Å; I598-S602 PolarHBondContact O-N 3.17Å
599G90.6Very high91Very high11 Ų1122 Ų2211%0.11312%0.123CC..Hα-helixtrans-65.2-42.8172.400000111.1R595 N597 L601 S602 L603R595-G599 PolarHBondContact O-N 3.33Å; N597-G599 VanDerWaalsContact C-N 3.31Å; N597-G599 PolarHBondContact O-N 2.99Å; G599-L601 VanDerWaalsContact C-N 3.26Å; G599-L601 PolarHBondContact O-N 2.6Å; G599-S602 PolarHBondContact O-N 3.15Å; G599-S602 PolarHBondContact O-OG 2.93Å; G599-L603 WeakPolarHBondContact O-CG 3.5Å; G599-L603 PolarHBondContact O-N 3Å
600K91.9Very high90.7Very high80 Ų8020.1 Ų20.135%0.34811%0.113SC..Hα-helixtrans-63-33.6173.6-174-177.9176.5-166.90112.5K468 T472 G596 N597 L603 L604K468-K600 VanDerWaalsContact CE-CE 3.45Å; T472-K600 HydrophobicContact CG2-CB 3.88Å; T472-K600 HydrophobicContact CG2-CD 3.92Å; T472-K600 HydrophobicContact CG2-CG 3.97Å; G596-K600 VanDerWaalsContact O-CB 3.3Å; G596-K600 WeakPolarHBondContact O-CB 3.35Å; G596-K600 PolarHBondContact O-N 3.13Å; N597-K600 WeakPolarHBondContact O-CB 3.33Å; N597-K600 PolarHBondContact O-N 3.41Å; K600-L603 PolarHBondContact O-N 3.48Å; K600-L604 HydrophobicContact CG-CD1 4.34Å; K600-L604 VanDerWaalsContact O-CG 3.29Å; K600-L604 WeakPolarHBondContact O-CG 3.46Å; K600-L604 PolarHBondContact O-N 3.33Å; K600-L604 VanDerWaalsContact O-N 3.08Å
601L92.4Very high90.3Very high1 Ų119.7 Ų19.71%0.00511%0.111CC..Hα-helixtrans-65.3-46.7176.7-15967.8000111.5I469 T472 V512 L513 I516 N597 I598 G599 L603 L604 D605 F671I469-L601 HydrophobicContact CG2-CD1 3.99Å; T472-L601 HydrophobicContact CG2-CB 4.23Å; T472-L601 HydrophobicContact CG2-CD1 4.12Å; V512-L601 HydrophobicContact CG1-CB 4.43Å; V512-L601 HydrophobicContact CG1-CD2 4.37Å; L513-L601 HydrophobicContact CD2-CD2 3.76Å; I516-L601 HydrophobicContact CD1-CD2 3.76Å; I516-L601 HydrophobicContact CD1-CG 3.74Å; N597-L601 PolarHBondContact O-N 2.97Å; I598-L601 WeakPolarHBondContact O-CB 3.45Å; I598-L601 PolarHBondContact O-N 3.4Å; G599-L601 VanDerWaalsContact C-N 3.26Å; G599-L601 PolarHBondContact O-N 2.6Å; L601-L603 VanDerWaalsContact C-N 3.31Å; L601-L603 PolarHBondContact O-N 2.86Å; L601-L604 PolarHBondContact O-N 3.06Å; L601-D605 PolarHBondContact O-N 3.48Å; L601-F671 HydrophobicContact CD1-CZ 3.69Å; L601-F671 HydrophobicContact CD2-CZ 4.33Å; L601-F671 HydrophobicContact CG-CZ 4.03Å
602S88.5Confident89.7Confident17 Ų1719.6 Ų19.612%0.11911%0.111CC..Hα-helixtrans-64.5-36.7176.563.60000112.2I598 G599 L604 D605 W606I598-S602 PolarHBondContact O-N 3.17Å; G599-S602 PolarHBondContact O-N 3.15Å; G599-S602 PolarHBondContact O-OG 2.93Å; S602-L604 VanDerWaalsContact C-N 3.33Å; S602-L604 PolarHBondContact O-N 2.78Å; S602-D605 PolarHBondContact O-N 3.41Å; S602-D605 VanDerWaalsContact O-N 3.13Å; S602-W606 WeakPolarHBondContact O-CB 3.48Å; S602-W606 PolarHBondContact O-N 3.12Å
603L86.4Confident89.4Confident21 Ų2119.3 Ų19.311%0.1111%0.109CC..Hα-helixtrans-64.9-35.1175.1-68.8174.3000113.6F97 W102 G599 K600 L601 D605 W606 V607F97-L603 HydrophobicContact CE1-CB 4.16Å; F97-L603 HydrophobicContact CZ-CB 3.81Å; F97-L603 WeakPolarHBondContact CZ-O 3.47Å; W102-L603 HydrophobicContact CD2-CD1 3.85Å; W102-L603 HydrophobicContact CG-CD1 4.26Å; W102-L603 HydrophobicContact CH2-CD1 4.37Å; W102-L603 HydrophobicContact CH2-CD2 3.34Å; W102-L603 HydrophobicContact CH2-CG 4.42Å; W102-L603 HydrophobicContact CZ2-CD1 3.64Å; W102-L603 HydrophobicContact CZ2-CD2 3.15Å; W102-L603 HydrophobicContact CZ2-CG 4.01Å; W102-L603 HydrophobicContact CZ3-CD2 4.11Å; W102-L603 VanDerWaalsContact NE1-CD1 3.32Å; G599-L603 WeakPolarHBondContact O-CG 3.5Å; G599-L603 PolarHBondContact O-N 3Å; K600-L603 PolarHBondContact O-N 3.48Å; L601-L603 VanDerWaalsContact C-N 3.31Å; L601-L603 PolarHBondContact O-N 2.86Å; L603-D605 VanDerWaalsContact C-N 3.25Å; L603-D605 PolarHBondContact O-N 2.94Å; L603-W606 HydrophobicContact CD2-CE3 3.83Å; L603-W606 HydrophobicContact CD2-CZ3 4.3Å; L603-W606 PolarHBondContact O-N 3.09Å; L603-V607 PolarHBondContact O-N 2.88Å
604L87.8Confident89.3Confident8 Ų817.4 Ų17.44%0.0429%0.093CC..Hα-helixtrans-73.4-16.3174.5-72167.9000112.8R465 I469 K600 L601 S602R465-L604 PolarHBondContact NH2-O 3.41Å; I469-L604 HydrophobicContact CG1-CB 4.39Å; I469-L604 HydrophobicContact CG1-CD1 4.03Å; K600-L604 HydrophobicContact CG-CD1 4.34Å; K600-L604 VanDerWaalsContact O-CG 3.29Å; K600-L604 WeakPolarHBondContact O-CG 3.46Å; K600-L604 PolarHBondContact O-N 3.33Å; K600-L604 VanDerWaalsContact O-N 3.08Å; L601-L604 PolarHBondContact O-N 3.06Å; S602-L604 VanDerWaalsContact C-N 3.33Å; S602-L604 PolarHBondContact O-N 2.78Å
605D86Confident89Confident36 Ų3617.1 Ų17.119%0.1939%0.091CC..Hα-helixtrans-86-41.4168.1-177.765.5000111.2T6 I516 L601 S602 L603 V607T6-D605 WeakPolarHBondContact CG2-OD1 3.17Å; I516-D605 HydrophobicContact CB-CB 4.1Å; I516-D605 HydrophobicContact CG2-CB 3.6Å; L601-D605 PolarHBondContact O-N 3.48Å; S602-D605 PolarHBondContact O-N 3.41Å; S602-D605 VanDerWaalsContact O-N 3.13Å; L603-D605 VanDerWaalsContact C-N 3.25Å; L603-D605 PolarHBondContact O-N 2.94Å; D605-V607 PolarHBondContact O-N 2.98Å
606W84.1Confident88.7Confident61 Ų6116.1 Ų16.123%0.2319%0.088CC..Hα-helixtrans-63.8-41.9-177.7-177.543.2000113.6W102 E306 Y309 I310 S602 L603 P608W102-W606 HydrophobicContact CH2-CZ3 4.34Å; E306-W606 HydrophobicContact CB-CH2 3.97Å; E306-W606 HydrophobicContact CB-CZ2 3.81Å; E306-W606 HydrophobicContact CG-CZ2 4.15Å; Y309-W606 AromaticContact CD1-CH2 3.43Å; Y309-W606 HydrophobicContact CD1-CH2 3.43Å; Y309-W606 VanDerWaalsContact CD1-CH2 3.43Å; Y309-W606 AromaticContact CD1-CZ2 3.59Å; Y309-W606 HydrophobicContact CD1-CZ2 3.59Å; Y309-W606 HydrophobicContact CD1-CZ3 4.27Å; Y309-W606 AromaticContact CE1-CH2 3.85Å; Y309-W606 HydrophobicContact CE1-CH2 3.85Å; Y309-W606 AromaticContact CE1-CZ2 3.94Å; Y309-W606 HydrophobicContact CE1-CZ2 3.94Å; Y309-W606 HydrophobicContact CE1-CZ3 4.32Å; Y309-W606 HydrophobicContact CG-CH2 4.5Å; Y309-W606 HydrophobicContact CG-CZ2 4.42Å; I310-W606 HydrophobicContact CD1-CH2 4.38Å; I310-W606 HydrophobicContact CD1-CZ3 4.28Å; I310-W606 HydrophobicContact CG1-CH2 4.11Å; I310-W606 HydrophobicContact CG1-CZ3 4.21Å; S602-W606 WeakPolarHBondContact O-CB 3.48Å; S602-W606 PolarHBondContact O-N 3.12Å; L603-W606 HydrophobicContact CD2-CE3 3.83Å; L603-W606 HydrophobicContact CD2-CZ3 4.3Å; L603-W606 PolarHBondContact O-N 3.09Å; W606-P608 WeakPolarHBondContact O-CD 3.23Å
607V85.9Confident88.7Confident2 Ų215 Ų151%0.0128%0.077CC..SBendtrans-110.888.6178.3-176.40000109.5W93 F97 F305 R465 L603 D605W93-V607 HydrophobicContact CH2-CG1 3.72Å; W93-V607 HydrophobicContact CZ2-CG1 3.73Å; F97-V607 HydrophobicContact CD2-CB 4.32Å; F97-V607 HydrophobicContact CD2-CG1 4.26Å; F97-V607 HydrophobicContact CD2-CG2 4.17Å; F97-V607 HydrophobicContact CE1-CB 4.28Å; F97-V607 HydrophobicContact CE2-CB 3.7Å; F97-V607 HydrophobicContact CE2-CG1 4.13Å; F97-V607 HydrophobicContact CE2-CG2 3.32Å; F97-V607 HydrophobicContact CZ-CB 3.64Å; F97-V607 HydrophobicContact CZ-CG1 4.39Å; F97-V607 HydrophobicContact CZ-CG2 3.61Å; F305-V607 HydrophobicContact CD1-CG1 4.2Å; F305-V607 HydrophobicContact CE1-CG1 3.93Å; R465-V607 PolarHBondContact NH1-O 3.16Å; R465-V607 PolarHBondContact NH2-O 2.61Å; L603-V607 PolarHBondContact O-N 2.88Å; D605-V607 PolarHBondContact O-N 2.98Å
608P86.5Confident88.6Confident7 Ų712.1 Ų12.15%0.0456%0.061CC..  trans-71.6-177.5-179.132.5-38000111.9Y5 W93 W606Y5-P608 HydrophobicContact CD1-CG 4.17Å; Y5-P608 HydrophobicContact CE1-CB 4.1Å; Y5-P608 HydrophobicContact CE1-CG 4Å; W93-P608 WeakPolarHBondContact CH2-O 3.21Å; W606-P608 WeakPolarHBondContact O-CD 3.23Å
609V88.7Confident88.3Confident3 Ų312.7 Ų12.72%0.0186%0.064CC..SBendtrans-58.6143.2162.4178.60000107.8Y5 Y90 F458 L611 Y613 L668Y5-V609 WeakPolarHBondContact CE1-O 3.37Å; Y5-V609 VanDerWaalsContact CZ-O 3.29Å; Y5-V609 PolarHBondContact OH-O 2.96Å; Y90-V609 HydrophobicContact CE2-CG1 4.4Å; F458-V609 HydrophobicContact CE2-CG1 4.14Å; V609-L611 PolarHBondContact O-N 3.04Å; V609-Y613 HydrophobicContact CG1-CD1 4.4Å; V609-L668 HydrophobicContact CB-CD1 4.44Å
610P85.9Confident88.3Confident3 Ų312.2 Ų12.22%0.0196%0.059CC..  trans-58.4136.4179-26.334.4000112.2W93 L294 V612 Y613 T614W93-P610 HydrophobicContact CH2-CG 4.42Å; W93-P610 HydrophobicContact CZ2-CG 4.32Å; L294-P610 HydrophobicContact CD1-CG 3.99Å; L294-P610 HydrophobicContact CD2-CB 4.08Å; L294-P610 HydrophobicContact CD2-CG 3.31Å; L294-P610 HydrophobicContact CG-CG 4.2Å; P610-V612 VanDerWaalsContact C-N 3.31Å; P610-V612 HydrophobicContact CB-CG1 4.11Å; P610-V612 PolarHBondContact O-N 3.35Å; P610-Y613 PolarHBondContact O-N 2.94Å; P610-Y613 VanDerWaalsContact O-N 3.17Å; P610-T614 PolarHBondContact O-N 2.76Å
611L86.9Confident88.3Confident1 Ų18.5 Ų8.51%0.0054%0.043CC..Hα-helixtrans-62.5-42.9-176.4176.461000110.9I3 Y5 L20 R23 V609 Y613 T614 Q615I3-L611 HydrophobicContact CG2-CD2 4.4Å; Y5-L611 HydrophobicContact CD1-CB 4.14Å; Y5-L611 HydrophobicContact CD1-CD1 4.04Å; Y5-L611 HydrophobicContact CE1-CB 4Å; Y5-L611 HydrophobicContact CE1-CD1 4.22Å; Y5-L611 HydrophobicContact CG-CD1 4.29Å; L20-L611 HydrophobicContact CB-CD1 3.95Å; L20-L611 HydrophobicContact CD1-CD1 4.31Å; L20-L611 HydrophobicContact CD2-CD1 4.01Å; L20-L611 HydrophobicContact CG-CD1 4.32Å; R23-L611 HydrophobicContact CB-CD2 4.08Å; R23-L611 HydrophobicContact CG-CD2 4.2Å; V609-L611 PolarHBondContact O-N 3.04Å; L611-Y613 PolarHBondContact O-N 3.13Å; L611-T614 WeakPolarHBondContact O-CA 3.39Å; L611-T614 WeakPolarHBondContact O-CB 3.31Å; L611-T614 PolarHBondContact O-N 2.84Å; L611-Q615 HydrophobicContact CD1-CG 4.11Å; L611-Q615 HydrophobicContact CG-CG 4.14Å; L611-Q615 WeakPolarHBondContact O-CG 3.37Å; L611-Q615 PolarHBondContact O-N 3.06Å
612V84.1Confident88.3Confident0 Ų010.3 Ų10.30%05%0.05CC..Hα-helixtrans-53.8-38.4177.1610000112.3I28 I31 V290 P610 Q615 V616I28-V612 HydrophobicContact CB-CG2 3.99Å; I28-V612 HydrophobicContact CG1-CG2 4.24Å; I31-V612 HydrophobicContact CD1-CB 4.49Å; I31-V612 HydrophobicContact CD1-CG2 4.27Å; V290-V612 HydrophobicContact CG2-CB 4.26Å; V290-V612 HydrophobicContact CG2-CG1 3.95Å; V290-V612 HydrophobicContact CG2-CG2 3.68Å; P610-V612 VanDerWaalsContact C-N 3.31Å; P610-V612 HydrophobicContact CB-CG1 4.11Å; P610-V612 PolarHBondContact O-N 3.35Å; V612-Q615 PolarHBondContact O-N 3.09Å; V612-V616 VanDerWaalsContact O-CG2 3.31Å; V612-V616 WeakPolarHBondContact O-CG2 3.37Å; V612-V616 PolarHBondContact O-N 2.74Å
613Y88.7Confident88.3Confident0 Ų010.5 Ų10.50%05%0.051CC..Hα-helixtrans-68-44.4178.1-165.1-178.6000111V86 Y90 W287 V290 F458 V609 P610 L611 Q615 V616 V617V86-Y613 HydrophobicContact CG1-CE1 4.49Å; Y90-Y613 HydrophobicContact CD2-CD1 4.34Å; Y90-Y613 HydrophobicContact CD2-CE1 4.42Å; W287-Y613 AromaticContact NE1-CE2 3.82Å; V290-Y613 HydrophobicContact CG1-CD1 4.37Å; V290-Y613 HydrophobicContact CG1-CD2 4.34Å; V290-Y613 HydrophobicContact CG1-CG 3.96Å; F458-Y613 HydrophobicContact CB-CE2 4.26Å; F458-Y613 HydrophobicContact CD2-CD1 4.21Å; F458-Y613 HydrophobicContact CD2-CD2 4.01Å; F458-Y613 HydrophobicContact CD2-CE1 4.19Å; F458-Y613 AromaticContact CD2-CE2 3.97Å; F458-Y613 HydrophobicContact CD2-CE2 3.97Å; F458-Y613 HydrophobicContact CD2-CG 4.12Å; F458-Y613 HydrophobicContact CE2-CG 4.4Å; V609-Y613 HydrophobicContact CG1-CD1 4.4Å; P610-Y613 PolarHBondContact O-N 2.94Å; P610-Y613 VanDerWaalsContact O-N 3.17Å; L611-Y613 PolarHBondContact O-N 3.13Å; Y613-Q615 VanDerWaalsContact C-N 3.28Å; Y613-Q615 PolarHBondContact O-N 3.48Å; Y613-V616 PolarHBondContact O-N 2.91Å; Y613-V617 HydrophobicContact CD2-CG2 3.82Å; Y613-V617 HydrophobicContact CE2-CG2 3.79Å; Y613-V617 VanDerWaalsContact O-CG2 3.25Å; Y613-V617 WeakPolarHBondContact O-CG2 3.46Å; Y613-V617 PolarHBondContact O-N 3.22Å
614T90.4Very high88.6Confident0 Ų010 Ų100%05%0.048CC..Hα-helixtrans-59.7-41.2174.5-54.40000111.2Y5 F17 L20 F458 P610 L611 T618Y5-T614 PolarHBondContact OH-OG1 3.44Å; F17-T614 HydrophobicContact CD1-CG2 4.35Å; F17-T614 HydrophobicContact CD2-CG2 4.28Å; F17-T614 HydrophobicContact CE1-CG2 4Å; F17-T614 HydrophobicContact CE2-CG2 3.97Å; F17-T614 HydrophobicContact CG-CG2 4.47Å; F17-T614 HydrophobicContact CZ-CG2 3.8Å; L20-T614 HydrophobicContact CD1-CG2 3.8Å; F458-T614 HydrophobicContact CZ-CG2 4.29Å; P610-T614 PolarHBondContact O-N 2.76Å; L611-T614 WeakPolarHBondContact O-CA 3.39Å; L611-T614 WeakPolarHBondContact O-CB 3.31Å; L611-T614 PolarHBondContact O-N 2.84Å; T614-T618 VanDerWaalsContact O-CB 3.25Å; T614-T618 WeakPolarHBondContact O-CB 3.45Å; T614-T618 PolarHBondContact O-N 2.98Å; T614-T618 PolarHBondContact O-OG1 2.96Å
615Q89.8Confident88.8Confident0 Ų010 Ų100%05%0.048CC..Hα-helixtrans-68.1-45.2179.1-69.5-179.4-25.600112.5L20 L21 I28 L611 V612 Y613 V617 T618 I619L20-Q615 PolarHBondContact O-NE2 3.11Å; L21-Q615 HydrophobicContact CD2-CB 3.89Å; L21-Q615 HydrophobicContact CD2-CG 3.98Å; I28-Q615 HydrophobicContact CB-CB 4.37Å; I28-Q615 HydrophobicContact CG2-CB 4.04Å; L611-Q615 HydrophobicContact CD1-CG 4.11Å; L611-Q615 HydrophobicContact CG-CG 4.14Å; L611-Q615 WeakPolarHBondContact O-CG 3.37Å; L611-Q615 PolarHBondContact O-N 3.06Å; V612-Q615 PolarHBondContact O-N 3.09Å; Y613-Q615 VanDerWaalsContact C-N 3.28Å; Y613-Q615 PolarHBondContact O-N 3.48Å; Q615-V617 VanDerWaalsContact C-N 3.33Å; Q615-V617 PolarHBondContact O-N 3.41Å; Q615-T618 PolarHBondContact O-N 2.8Å; Q615-I619 WeakPolarHBondContact O-CB 3.16Å; Q615-I619 VanDerWaalsContact O-CG1 3.26Å; Q615-I619 WeakPolarHBondContact O-CG1 3.44Å; Q615-I619 PolarHBondContact O-N 3.01Å
616V88.4Confident89Confident1 Ų111.9 Ų11.91%0.0066%0.063CC..Hα-helixtrans-55.8-48.6176.7167.80000110.8I28 F283 W287 V290 V612 Y613 I619 A620I28-V616 HydrophobicContact CD1-CB 4.4Å; I28-V616 HydrophobicContact CD1-CG2 3.41Å; I28-V616 VanDerWaalsContact CD1-CG2 3.41Å; I28-V616 HydrophobicContact CG1-CG2 4Å; F283-V616 HydrophobicContact CD2-CG1 4.4Å; W287-V616 HydrophobicContact CB-CG1 4.23Å; W287-V616 HydrophobicContact CG-CG1 4.41Å; V290-V616 HydrophobicContact CG2-CB 4.46Å; V290-V616 HydrophobicContact CG2-CG2 3.73Å; V612-V616 VanDerWaalsContact O-CG2 3.31Å; V612-V616 WeakPolarHBondContact O-CG2 3.37Å; V612-V616 PolarHBondContact O-N 2.74Å; Y613-V616 PolarHBondContact O-N 2.91Å; V616-I619 PolarHBondContact O-N 3.47Å; V616-A620 WeakPolarHBondContact O-CB 3.18Å; V616-A620 PolarHBondContact O-N 2.98Å
617V91.1Very high89.3Confident0 Ų09.2 Ų9.20%05%0.053CC..Hα-helixtrans-66.5-41.8-178.81790000110.7V454 L455 F458 Y613 Q615 A620 V621 L661V454-V617 HydrophobicContact CG1-CB 4.12Å; V454-V617 HydrophobicContact CG1-CG1 4.23Å; V454-V617 HydrophobicContact CG1-CG2 3.55Å; L455-V617 HydrophobicContact CD1-CG1 3.85Å; F458-V617 HydrophobicContact CB-CB 4.48Å; F458-V617 HydrophobicContact CB-CG1 4.13Å; F458-V617 HydrophobicContact CB-CG2 3.63Å; F458-V617 HydrophobicContact CD1-CB 4.3Å; F458-V617 HydrophobicContact CD1-CG1 3.84Å; F458-V617 HydrophobicContact CD1-CG2 4.21Å; F458-V617 HydrophobicContact CD2-CG2 3.83Å; F458-V617 HydrophobicContact CE1-CG1 4.47Å; F458-V617 HydrophobicContact CG-CB 4.23Å; F458-V617 HydrophobicContact CG-CG1 4.07Å; F458-V617 HydrophobicContact CG-CG2 3.63Å; Y613-V617 HydrophobicContact CD2-CG2 3.82Å; Y613-V617 HydrophobicContact CE2-CG2 3.79Å; Y613-V617 VanDerWaalsContact O-CG2 3.25Å; Y613-V617 WeakPolarHBondContact O-CG2 3.46Å; Y613-V617 PolarHBondContact O-N 3.22Å; Q615-V617 VanDerWaalsContact C-N 3.33Å; Q615-V617 PolarHBondContact O-N 3.41Å; V617-A620 WeakPolarHBondContact O-CB 3.25Å; V617-A620 PolarHBondContact O-N 3.3Å; V617-V621 WeakPolarHBondContact O-CG2 3.18Å; V617-V621 PolarHBondContact O-N 3.3Å; V617-V621 VanDerWaalsContact O-N 3.11Å; V617-L661 HydrophobicContact CG1-CD1 3.92Å
618T91.7Very high89.4Confident1 Ų19.1 Ų9.11%0.0065%0.053CC..Hα-helixtrans-63.6-48.2177.8-60.30000111F17 L21 T614 Q615 A620 V621 Y622F17-T618 HydrophobicContact CB-CG2 3.9Å; F17-T618 WeakPolarHBondContact CD2-OG1 3.46Å; L21-T618 HydrophobicContact CD1-CG2 3.98Å; L21-T618 HydrophobicContact CD2-CG2 3.92Å; L21-T618 HydrophobicContact CG-CG2 3.99Å; T614-T618 VanDerWaalsContact O-CB 3.25Å; T614-T618 WeakPolarHBondContact O-CB 3.45Å; T614-T618 PolarHBondContact O-N 2.98Å; T614-T618 PolarHBondContact O-OG1 2.96Å; Q615-T618 PolarHBondContact O-N 2.8Å; T618-A620 VanDerWaalsContact C-N 3.3Å; T618-A620 PolarHBondContact O-N 3.48Å; T618-V621 PolarHBondContact O-N 3.45Å; T618-Y622 HydrophobicContact CG2-CD2 3.51Å; T618-Y622 HydrophobicContact CG2-CE2 3.7Å; T618-Y622 WeakPolarHBondContact O-CB 3.16Å; T618-Y622 VanDerWaalsContact O-CD2 3.31Å; T618-Y622 WeakPolarHBondContact O-CD2 3.27Å; T618-Y622 PolarHBondContact O-N 2.7Å
619I89.6Confident89.6Confident13 Ų139.8 Ų9.87%0.0676%0.056CC..Hα-helixtrans-58.5-43.8176.4-70.2166.7000110.2L21 I28 Y29 Q615 V616 V621 S623L21-I619 HydrophobicContact CD1-CG1 4.11Å; L21-I619 HydrophobicContact CD2-CD1 4.1Å; L21-I619 HydrophobicContact CD2-CG1 3.62Å; I28-I619 HydrophobicContact CD1-CD1 4Å; I28-I619 HydrophobicContact CG2-CD1 3.71Å; Y29-I619 HydrophobicContact CE1-CD1 4.34Å; Q615-I619 WeakPolarHBondContact O-CB 3.16Å; Q615-I619 VanDerWaalsContact O-CG1 3.26Å; Q615-I619 WeakPolarHBondContact O-CG1 3.44Å; Q615-I619 PolarHBondContact O-N 3.01Å; V616-I619 PolarHBondContact O-N 3.47Å; I619-V621 PolarHBondContact O-N 3.42Å; I619-S623 WeakPolarHBondContact O-CA 3.33Å; I619-S623 WeakPolarHBondContact O-CB 3.33Å; I619-S623 PolarHBondContact O-N 2.91Å; I619-S623 PolarHBondContact O-OG 3.33Å
620A89.1Confident89.5Confident2 Ų211.9 Ų11.92%0.0177%0.067CC..Hα-helixtrans-57.4-51.2179.200000112.1F283 I449 V616 V617 T618 F624F283-A620 HydrophobicContact CD2-CB 3.53Å; F283-A620 HydrophobicContact CE2-CB 3.42Å; F283-A620 VanDerWaalsContact CE2-CB 3.42Å; I449-A620 HydrophobicContact CG2-CB 4.37Å; V616-A620 WeakPolarHBondContact O-CB 3.18Å; V616-A620 PolarHBondContact O-N 2.98Å; V617-A620 WeakPolarHBondContact O-CB 3.25Å; V617-A620 PolarHBondContact O-N 3.3Å; T618-A620 VanDerWaalsContact C-N 3.3Å; T618-A620 PolarHBondContact O-N 3.48Å; A620-F624 WeakPolarHBondContact O-CB 3.48Å; A620-F624 PolarHBondContact O-N 3.11Å; A620-F624 VanDerWaalsContact O-N 3.13Å
621V92.7Very high89.4Confident1 Ų111.9 Ų11.91%0.0067%0.067CC..Hα-helixtrans-67.9-47.7-177.41770000111.1I451 L455 V617 T618 I619 F624 F625 I658 L661I451-V621 HydrophobicContact CG2-CG2 3.85Å; L455-V621 HydrophobicContact CD1-CG2 4.31Å; L455-V621 HydrophobicContact CD2-CG2 4.23Å; V617-V621 WeakPolarHBondContact O-CG2 3.18Å; V617-V621 PolarHBondContact O-N 3.3Å; V617-V621 VanDerWaalsContact O-N 3.11Å; T618-V621 PolarHBondContact O-N 3.45Å; I619-V621 PolarHBondContact O-N 3.42Å; V621-F624 WeakPolarHBondContact O-CB 3.45Å; V621-F624 PolarHBondContact O-N 3.33Å; V621-F625 HydrophobicContact CG1-CD2 4.08Å; V621-F625 HydrophobicContact CG1-CE2 3.95Å; V621-F625 VanDerWaalsContact O-CD2 3.22Å; V621-F625 WeakPolarHBondContact O-CD2 3.48Å; V621-F625 PolarHBondContact O-N 3.29Å; V621-I658 HydrophobicContact CG1-CD1 3.53Å; V621-I658 HydrophobicContact CG1-CG1 4.27Å; V621-L661 HydrophobicContact CB-CD2 3.99Å; V621-L661 HydrophobicContact CG1-CD2 3.94Å; V621-L661 HydrophobicContact CG2-CD2 4.31Å
622Y92Very high89.2Confident40 Ų4015 Ų1516%0.1578%0.078CC..Hα-helixtrans-69.1-38.1-179.1-81.4-81.2000112.1L18 D408 T618 F624 F625 C626 I658 L661L18-Y622 HydrophobicContact CD1-CE1 4.06Å; L18-Y622 HydrophobicContact CD2-CD1 3.98Å; L18-Y622 HydrophobicContact CD2-CD2 3.85Å; L18-Y622 HydrophobicContact CD2-CE1 3.99Å; L18-Y622 HydrophobicContact CD2-CE2 3.86Å; L18-Y622 HydrophobicContact CD2-CG 3.92Å; L18-Y622 HydrophobicContact CG-CE1 4.17Å; L18-Y622 HydrophobicContact CG-CE2 4.12Å; D408-Y622 PolarHBondContact OD1-OH 3.34Å; T618-Y622 HydrophobicContact CG2-CD2 3.51Å; T618-Y622 HydrophobicContact CG2-CE2 3.7Å; T618-Y622 WeakPolarHBondContact O-CB 3.16Å; T618-Y622 VanDerWaalsContact O-CD2 3.31Å; T618-Y622 WeakPolarHBondContact O-CD2 3.27Å; T618-Y622 PolarHBondContact O-N 2.7Å; Y622-F624 VanDerWaalsContact C-N 3.32Å; Y622-F624 PolarHBondContact O-N 3.15Å; Y622-F625 PolarHBondContact O-N 3.1Å; Y622-C626 WeakPolarHBondContact O-CB 3.41Å; Y622-C626 PolarHBondContact O-N 2.82Å; Y622-C626 PolarHBondContact O-SG 3.46Å; Y622-I658 HydrophobicContact CE1-CD1 4.44Å; Y622-L661 HydrophobicContact CD2-CD2 4.3Å; Y622-L661 HydrophobicContact CE2-CD2 3.88Å
623S89.2Confident88.8Confident20 Ų2015.2 Ų15.214%0.148%0.079CC..Hα-helixtrans-61.7-42.2176.1-58.70000111.1I619 F625 C626 L627I619-S623 WeakPolarHBondContact O-CA 3.33Å; I619-S623 WeakPolarHBondContact O-CB 3.33Å; I619-S623 PolarHBondContact O-N 2.91Å; I619-S623 PolarHBondContact O-OG 3.33Å; S623-F625 PolarHBondContact O-N 3.47Å; S623-C626 WeakPolarHBondContact O-CB 3.45Å; S623-C626 PolarHBondContact O-N 3.37Å; S623-L627 VanDerWaalsContact O-CG 3.31Å; S623-L627 WeakPolarHBondContact O-CG 3.4Å; S623-L627 PolarHBondContact O-N 2.91Å
624F91.6Very high87.9Confident12 Ų1216.3 Ų16.35%0.0538%0.084CC..Hα-helixtrans-57.3-47.2173.7174.6-97.1000113.1N446 I451 A620 V621 Y622 C626 L627 C628 E653 Y657N446-F624 VanDerWaalsContact CG-CE2 3.47Å; N446-F624 VanDerWaalsContact ND2-CE2 3.32Å; N446-F624 WeakPolarHBondContact ND2-CE2 3.33Å; N446-F624 WeakPolarHBondContact OD1-CD2 3.46Å; N446-F624 WeakPolarHBondContact OD1-CE2 3.3Å; I451-F624 HydrophobicContact CD1-CB 3.1Å; I451-F624 HydrophobicContact CD1-CD1 3.61Å; I451-F624 HydrophobicContact CD1-CD2 3Å; I451-F624 HydrophobicContact CD1-CE1 4.22Å; I451-F624 HydrophobicContact CD1-CE2 3.69Å; I451-F624 HydrophobicContact CD1-CG 2.95Å; I451-F624 HydrophobicContact CD1-CZ 4.25Å; I451-F624 HydrophobicContact CG1-CB 4.18Å; I451-F624 HydrophobicContact CG1-CD2 4.38Å; I451-F624 HydrophobicContact CG1-CG 4.36Å; A620-F624 WeakPolarHBondContact O-CB 3.48Å; A620-F624 PolarHBondContact O-N 3.11Å; A620-F624 VanDerWaalsContact O-N 3.13Å; V621-F624 WeakPolarHBondContact O-CB 3.45Å; V621-F624 PolarHBondContact O-N 3.33Å; Y622-F624 VanDerWaalsContact C-N 3.32Å; Y622-F624 PolarHBondContact O-N 3.15Å; F624-C626 VanDerWaalsContact C-N 3.35Å; F624-C626 PolarHBondContact O-N 3.44Å; F624-L627 CarbonylContact O-C 3.53Å; F624-L627 WeakPolarHBondContact O-CB 3Å; F624-L627 PolarHBondContact O-N 3.13Å; F624-L627 VanDerWaalsContact O-N 3.17Å; F624-C628 PolarHBondContact O-N 3.44Å; F624-C628 PolarHBondContact O-SG 2.82Å; F624-C628 VanDerWaalsContact O-SG 3.37Å; F624-E653 VanDerWaalsContact CZ-OE2 3.27Å; F624-E653 WeakPolarHBondContact CZ-OE2 3.38Å; F624-Y657 HydrophobicContact CD1-CD2 4.12Å; F624-Y657 HydrophobicContact CD1-CE2 4.48Å; F624-Y657 AromaticContact CE1-CD2 3.66Å; F624-Y657 HydrophobicContact CE1-CD2 3.66Å; F624-Y657 AromaticContact CE1-CE2 3.72Å; F624-Y657 HydrophobicContact CE1-CE2 3.72Å; F624-Y657 HydrophobicContact CZ-CD2 4.18Å; F624-Y657 AromaticContact CZ-CE2 3.75Å; F624-Y657 HydrophobicContact CZ-CE2 3.75Å
625F93Very high86.2Confident6 Ų621.6 Ų21.63%0.02611%0.113CC..Hα-helixtrans-69.8-33.3177.9-73.9-66.2000112.6F412 V621 Y622 S623 L627 C628 L629 E653 F654 Y657 I658F412-F625 HydrophobicContact CD2-CB 4.23Å; F412-F625 HydrophobicContact CE2-CB 3.92Å; F412-F625 AromaticContact CE2-CD1 3.98Å; F412-F625 HydrophobicContact CE2-CD1 3.98Å; F412-F625 HydrophobicContact CE2-CG 4.37Å; F412-F625 HydrophobicContact CZ-CD1 4.28Å; V621-F625 HydrophobicContact CG1-CD2 4.08Å; V621-F625 HydrophobicContact CG1-CE2 3.95Å; V621-F625 VanDerWaalsContact O-CD2 3.22Å; V621-F625 WeakPolarHBondContact O-CD2 3.48Å; V621-F625 PolarHBondContact O-N 3.29Å; Y622-F625 PolarHBondContact O-N 3.1Å; S623-F625 PolarHBondContact O-N 3.47Å; F625-L627 VanDerWaalsContact C-N 3.31Å; F625-L627 PolarHBondContact O-N 3.22Å; F625-C628 HydrophobicContact CD1-CB 4.48Å; F625-C628 WeakPolarHBondContact O-CB 3.35Å; F625-C628 PolarHBondContact O-N 3.5Å; F625-L629 WeakPolarHBondContact O-CG 3.25Å; F625-L629 PolarHBondContact O-N 3.09Å; F625-E653 HydrophobicContact CE1-CB 4.44Å; F625-F654 HydrophobicContact CD1-CB 4.43Å; F625-F654 AromaticContact CD1-CD2 3.56Å; F625-F654 HydrophobicContact CD1-CD2 3.56Å; F625-F654 HydrophobicContact CD1-CE2 4.29Å; F625-F654 HydrophobicContact CD1-CG 4.42Å; F625-F654 HydrophobicContact CD2-CD2 4.28Å; F625-F654 VanDerWaalsContact CE1-CA 3.49Å; F625-F654 HydrophobicContact CE1-CB 3.75Å; F625-F654 AromaticContact CE1-CD2 3.71Å; F625-F654 HydrophobicContact CE1-CD2 3.71Å; F625-F654 HydrophobicContact CE1-CG 4.13Å; F625-F654 HydrophobicContact CE2-CD2 4.41Å; F625-F654 AromaticContact CG-CD2 3.89Å; F625-F654 HydrophobicContact CG-CD2 3.89Å; F625-F654 HydrophobicContact CG-CE2 4.2Å; F625-F654 HydrophobicContact CZ-CB 4.07Å; F625-F654 HydrophobicContact CZ-CD2 4.17Å; F625-F654 HydrophobicContact CZ-CG 4.37Å; F625-Y657 HydrophobicContact CE2-CD2 4.27Å; F625-Y657 AromaticContact CZ-CD2 3.89Å; F625-Y657 HydrophobicContact CZ-CD2 3.89Å; F625-Y657 HydrophobicContact CZ-CG 4.4Å; F625-I658 HydrophobicContact CD2-CD1 3.87Å; F625-I658 HydrophobicContact CD2-CG1 3.79Å; F625-I658 HydrophobicContact CE2-CD1 4.05Å; F625-I658 HydrophobicContact CE2-CG1 3.59Å; F625-I658 HydrophobicContact CZ-CG1 4.36Å
626C90.4Very high84.4Confident76 Ų7626.3 Ų26.351%0.51415%0.151SC..Hα-helixtrans-59.6-41.2168.7-71.40000111.8Y622 S623 F624 L629Y622-C626 WeakPolarHBondContact O-CB 3.41Å; Y622-C626 PolarHBondContact O-N 2.82Å; Y622-C626 PolarHBondContact O-SG 3.46Å; S623-C626 WeakPolarHBondContact O-CB 3.45Å; S623-C626 PolarHBondContact O-N 3.37Å; F624-C626 VanDerWaalsContact C-N 3.35Å; F624-C626 PolarHBondContact O-N 3.44Å; C626-L629 WeakPolarHBondContact O-CB 3.37Å; C626-L629 PolarHBondContact O-N 3.06Å
627L88.9Confident82.6Confident6 Ų629.8 Ų29.83%0.03119%0.187CC..Hα-helixtrans-67-39.6173.6-66.7-173.4000111.9I279 F442 I449 S623 F624 F625 L629 L630 S631I279-L627 HydrophobicContact CD1-CD2 4.43Å; F442-L627 HydrophobicContact CB-CD2 4.34Å; F442-L627 HydrophobicContact CD1-CD2 3.3Å; F442-L627 HydrophobicContact CE1-CD2 3.79Å; F442-L627 HydrophobicContact CG-CD2 4.07Å; I449-L627 HydrophobicContact CD1-CD1 3.68Å; S623-L627 VanDerWaalsContact O-CG 3.31Å; S623-L627 WeakPolarHBondContact O-CG 3.4Å; S623-L627 PolarHBondContact O-N 2.91Å; F624-L627 CarbonylContact O-C 3.53Å; F624-L627 WeakPolarHBondContact O-CB 3Å; F624-L627 PolarHBondContact O-N 3.13Å; F624-L627 VanDerWaalsContact O-N 3.17Å; F625-L627 VanDerWaalsContact C-N 3.31Å; F625-L627 PolarHBondContact O-N 3.22Å; L627-L629 VanDerWaalsContact C-N 3.3Å; L627-L629 PolarHBondContact O-N 3.33Å; L627-L630 PolarHBondContact O-N 3.34Å; L627-S631 VanDerWaalsContact O-CB 3.27Å; L627-S631 WeakPolarHBondContact O-CB 3.26Å; L627-S631 PolarHBondContact O-N 2.91Å; L627-S631 PolarHBondContact O-OG 3.38Å
628C89.7Confident80.5Confident0 Ų031.7 Ų31.70%020%0.201CC..Hα-helixtrans-60.8-35.6175.2-74.50000112.7F412 N446 F624 F625 L630 S631 R632 V650F412-C628 HydrophobicContact CZ-CB 4.43Å; N446-C628 PolarHBondContact ND2-SG 3.24Å; F624-C628 PolarHBondContact O-N 3.44Å; F624-C628 PolarHBondContact O-SG 2.82Å; F624-C628 VanDerWaalsContact O-SG 3.37Å; F625-C628 HydrophobicContact CD1-CB 4.48Å; F625-C628 WeakPolarHBondContact O-CB 3.35Å; F625-C628 PolarHBondContact O-N 3.5Å; C628-L630 PolarHBondContact O-N 2.8Å; C628-S631 WeakPolarHBondContact CA-OG 3.27Å; C628-R632 WeakPolarHBondContact O-CB 3.49Å; C628-R632 PolarHBondContact O-N 2.94Å; C628-R632 VanDerWaalsContact O-N 3.1Å; C628-V650 HydrophobicContact CB-CG1 4.21Å
629L89.9Confident78.4Confident20 Ų2041.7 Ų41.711%0.10524%0.244CC..Hα-helixtrans-60.3-27.1176.6-74.6172.5000113.3F412 I415 Y416 L419 F625 C626 L627 Q633F412-L629 HydrophobicContact CD2-CD1 4.49Å; F412-L629 HydrophobicContact CD2-CD2 3.79Å; F412-L629 HydrophobicContact CD2-CG 4.05Å; F412-L629 HydrophobicContact CE1-CD2 4.5Å; F412-L629 HydrophobicContact CE2-CD1 4.46Å; F412-L629 HydrophobicContact CE2-CD2 3.53Å; F412-L629 HydrophobicContact CE2-CG 3.62Å; F412-L629 HydrophobicContact CG-CD2 4.39Å; F412-L629 HydrophobicContact CZ-CD2 3.9Å; F412-L629 HydrophobicContact CZ-CG 4.31Å; I415-L629 HydrophobicContact CB-CD1 4.35Å; I415-L629 HydrophobicContact CB-CD2 4.22Å; I415-L629 HydrophobicContact CG2-CD1 3.73Å; I415-L629 HydrophobicContact CG2-CD2 4.03Å; I415-L629 HydrophobicContact CG2-CG 4.45Å; Y416-L629 HydrophobicContact CD2-CD2 4.37Å; L419-L629 HydrophobicContact CD1-CB 4.19Å; F625-L629 WeakPolarHBondContact O-CG 3.25Å; F625-L629 PolarHBondContact O-N 3.09Å; C626-L629 WeakPolarHBondContact O-CB 3.37Å; C626-L629 PolarHBondContact O-N 3.06Å; L627-L629 VanDerWaalsContact C-N 3.3Å; L627-L629 PolarHBondContact O-N 3.33Å; L629-Q633 WeakPolarHBondContact O-CG 3.25Å; L629-Q633 PolarHBondContact O-NE2 2.98Å
630L86.4Confident76.3Confident47 Ų4745.8 Ų45.825%0.24628%0.28CS..Hα-helixtrans-101.4-41.8-179.9-61175.6000111.8L419 F435 S439 F442 L627 C628L419-L630 HydrophobicContact CD1-CD2 4.25Å; F435-L630 HydrophobicContact CE2-CD2 4.14Å; F435-L630 HydrophobicContact CZ-CD2 4.05Å; S439-L630 WeakPolarHBondContact CB-O 3.46Å; S439-L630 PolarHBondContact OG-O 3.32Å; F442-L630 HydrophobicContact CB-CB 4.41Å; F442-L630 HydrophobicContact CD2-CB 3.71Å; F442-L630 HydrophobicContact CD2-CD1 3.6Å; F442-L630 HydrophobicContact CD2-CG 4.3Å; F442-L630 HydrophobicContact CE2-CB 4.33Å; F442-L630 HydrophobicContact CE2-CD1 3.35Å; F442-L630 HydrophobicContact CE2-CG 4.46Å; F442-L630 HydrophobicContact CG-CB 4.32Å; F442-L630 HydrophobicContact CG-CD1 4.39Å; F442-L630 HydrophobicContact CZ-CD1 3.97Å; L627-L630 PolarHBondContact O-N 3.34Å; C628-L630 PolarHBondContact O-N 2.8Å
631S83.8Confident74.1Confident3 Ų352.3 Ų52.32%0.02131%0.314CS..Hα-helixtrans-78.8-28.6-172.358.30000115.1S439 M443 L627 C628S439-S631 WeakPolarHBondContact O-CA 3.46Å; S439-S631 WeakPolarHBondContact OG-CA 3.47Å; S439-S631 PolarHBondContact OG-O 3.19Å; M443-S631 VanDerWaalsContact CA-CB 3.45Å; L627-S631 VanDerWaalsContact O-CB 3.27Å; L627-S631 WeakPolarHBondContact O-CB 3.26Å; L627-S631 PolarHBondContact O-N 2.91Å; L627-S631 PolarHBondContact O-OG 3.38Å; C628-S631 WeakPolarHBondContact CA-OG 3.27Å
632R81.9Confident71.9Confident67 Ų6754.7 Ų54.725%0.25333%0.325SS..THydrogen-bonded Turntrans-108.523-174-56.4-171.2-179.3-164.76.4112.7Y416 C628 V650 E653Y416-R632 PolarHBondContact OH-O 3.45Å; C628-R632 WeakPolarHBondContact O-CB 3.49Å; C628-R632 PolarHBondContact O-N 2.94Å; C628-R632 VanDerWaalsContact O-N 3.1Å; R632-V650 HydrophobicContact CB-CG2 4Å; R632-V650 HydrophobicContact CG-CG2 4.37Å; R632-E653 IonicContact CZ-OE1 2.68Å; R632-E653 IonicContact CZ-OE2 2.79Å; R632-E653 IonicContact NH1-OE1 2.95Å; R632-E653 PolarHBondContact NH1-OE1 2.97Å; R632-E653 IonicContact NH1-OE2 2.82Å; R632-E653 PolarHBondContact NH1-OE2 2.99Å; R632-E653 VanDerWaalsContact NH2-CD 3.3Å; R632-E653 IonicContact NH2-OE1 3.34Å; R632-E653 PolarHBondContact NH2-OE1 2.76Å; R632-E653 IonicContact NH2-OE2 3.1Å; R632-E653 PolarHBondContact NH2-OE2 3.32Å
633Q77.7Confident69.9Low4 Ų458.4 Ų58.42%0.01936%0.357CS..SBendtrans-74.2-35.3172.6-70.5-72.1-1000111.3Y416 F435 L629Y416-Q633 HydrophobicContact CE2-CG 4.49Å; Y416-Q633 PolarHBondContact O-NE2 2.86Å; Y416-Q633 VanDerWaalsContact O-NE2 3.09Å; F435-Q633 HydrophobicContact CE1-CB 4.05Å; F435-Q633 HydrophobicContact CE1-CG 4.06Å; F435-Q633 HydrophobicContact CZ-CG 4.21Å; L629-Q633 WeakPolarHBondContact O-CG 3.25Å; L629-Q633 PolarHBondContact O-NE2 2.98Å
634F68.7Low68.1Low24 Ų2464 Ų6411%0.10538%0.384CS..  trans-138.2127-171-53.8-64.8000111.7Y423 H424 F435Y423-F634 HydrophobicContact CD1-CD1 4.42Å; Y423-F634 AromaticContact CD1-CE1 3.31Å; Y423-F634 HydrophobicContact CD1-CE1 3.31Å; Y423-F634 AromaticContact CD1-CE2 4Å; Y423-F634 HydrophobicContact CD1-CE2 4Å; Y423-F634 AromaticContact CD1-CZ 3.07Å; Y423-F634 HydrophobicContact CD1-CZ 3.07Å; Y423-F634 HydrophobicContact CD2-CD2 4.43Å; Y423-F634 HydrophobicContact CD2-CE1 4.27Å; Y423-F634 AromaticContact CD2-CE2 3.44Å; Y423-F634 HydrophobicContact CD2-CE2 3.44Å; Y423-F634 VanDerWaalsContact CD2-CE2 3.44Å; Y423-F634 AromaticContact CD2-CZ 3.4Å; Y423-F634 HydrophobicContact CD2-CZ 3.4Å; Y423-F634 VanDerWaalsContact CD2-CZ 3.4Å; Y423-F634 AromaticContact CE1-CD1 4Å; Y423-F634 HydrophobicContact CE1-CD1 4Å; Y423-F634 AromaticContact CE1-CE1 3.26Å; Y423-F634 HydrophobicContact CE1-CE1 3.26Å; Y423-F634 HydrophobicContact CE1-CE2 4.16Å; Y423-F634 AromaticContact CE1-CZ 3.41Å; Y423-F634 HydrophobicContact CE1-CZ 3.41Å; Y423-F634 VanDerWaalsContact CE1-CZ 3.41Å; Y423-F634 HydrophobicContact CE2-CD2 4.18Å; Y423-F634 HydrophobicContact CE2-CE1 4.21Å; Y423-F634 AromaticContact CE2-CE2 3.6Å; Y423-F634 HydrophobicContact CE2-CE2 3.6Å; Y423-F634 AromaticContact CE2-CZ 3.68Å; Y423-F634 HydrophobicContact CE2-CZ 3.68Å; Y423-F634 AromaticContact CG-CE1 3.86Å; Y423-F634 HydrophobicContact CG-CE1 3.86Å; Y423-F634 AromaticContact CG-CE2 3.66Å; Y423-F634 HydrophobicContact CG-CE2 3.66Å; Y423-F634 AromaticContact CG-CZ 3.09Å; Y423-F634 HydrophobicContact CG-CZ 3.09Å; Y423-F634 AromaticContact CZ-CE1 3.74Å; Y423-F634 AromaticContact CZ-CE2 3.97Å; Y423-F634 AromaticContact CZ-CZ 3.7Å; H424-F634 AromaticContact NE2-CE1 3.82Å; F435-F634 AromaticContact CD1-CD2 3.9Å; F435-F634 HydrophobicContact CD1-CD2 3.9Å; F435-F634 AromaticContact CD1-CE2 3.41Å; F435-F634 HydrophobicContact CD1-CE2 3.41Å; F435-F634 VanDerWaalsContact CD1-CE2 3.41Å; F435-F634 AromaticContact CE1-CD2 3.94Å; F435-F634 HydrophobicContact CE1-CD2 3.94Å; F435-F634 AromaticContact CE1-CE2 3.38Å; F435-F634 HydrophobicContact CE1-CE2 3.38Å; F435-F634 HydrophobicContact CE1-CZ 4.47Å
635N55.9Low66.9Low111 Ų11165.5 Ų65.559%0.59439%0.392SS*.  trans-90.7111.3162.9-74.4-19.6000106.9G637 S638N635-G637 PolarHBondContact O-N 3.47Å; N635-S638 PolarHBondContact O-N 3.39Å
636A51.1Low66.1Low98 Ų9869.1 Ų69.181%0.8142%0.415SS*.THydrogen-bonded Turntrans-61.49.1-169.200000116.7
637G49.6Very low65.8Low74 Ų7466 Ų6676%0.76339%0.394SS*.THydrogen-bonded Turntrans-133.80.1-175.900000117.3N635N635-G637 PolarHBondContact O-N 3.47Å
638S47.4Very low65.6Low41 Ų4171.7 Ų71.729%0.28742%0.418SS..  trans-114.766.4-167.762.50000115.5N635 A640 E642N635-S638 PolarHBondContact O-N 3.39Å; S638-A640 PolarHBondContact O-N 3.38Å; S638-E642 WeakPolarHBondContact CA-OE1 3.44Å; S638-E642 PolarHBondContact N-OE1 3.01Å; S638-E642 WeakPolarHBondContact O-CG 3.35Å; S638-E642 PolarHBondContact OG-OE1 3.2Å
639K48.7Very low65.3Low210 Ų21079 Ų7991%0.91345%0.45SS*.THydrogen-bonded Turntrans-48.9-19.9179.6-72.9-172.2177.7-178.60116.6
640A45.4Very low65.3Low100 Ų10078.4 Ų78.483%0.82645%0.448SS*.THydrogen-bonded Turntrans-104.5-21.5-165.600000116.5S638S638-A640 PolarHBondContact O-N 3.38Å
641L41.9Very low65.6Low138 Ų13877.6 Ų77.672%0.72344%0.443SS*.THydrogen-bonded Turntrans-98.3-3.7179.7-144.376.1000113S643 N645L641-S643 PolarHBondContact O-N 3.37Å; L641-N645 PolarHBondContact O-OD1 3.31Å
642E47.4Very low65.9Low51 Ų5180 Ų8024%0.23846%0.456CS..G310 helixtrans-80.4-11.7-156.1-83.9168.9-165.400117.6S638 I644 N645S638-E642 WeakPolarHBondContact CA-OE1 3.44Å; S638-E642 PolarHBondContact N-OE1 3.01Å; S638-E642 WeakPolarHBondContact O-CG 3.35Å; S638-E642 PolarHBondContact OG-OE1 3.2Å; E642-I644 VanDerWaalsContact C-N 3.32Å; E642-I644 PolarHBondContact O-N 3.18Å; E642-N645 WeakPolarHBondContact CG-ND2 3.44Å
643S49.9Very low66.4Low119 Ų11978.8 Ų78.883%0.83245%0.453SS*.G310 helixtrans-74.9-18.8-172.7650000114.5L641L641-S643 PolarHBondContact O-N 3.37Å
644I51.7Low67.2Low136 Ų13678.9 Ų78.970%0.69745%0.453SS*.G310 helixtrans-145.358.4177.5-48.3175.9000108.8E642 V646E642-I644 VanDerWaalsContact C-N 3.32Å; E642-I644 PolarHBondContact O-N 3.18Å; I644-V646 VanDerWaalsContact C-N 3.35Å; I644-V646 PolarHBondContact O-N 3.22Å
645N65.7Low68.4Low44 Ų4479.1 Ų79.124%0.23546%0.455CS..  trans-74.287.9-179.9-88-16.8000110.5L641 E642 P647L641-N645 PolarHBondContact O-OD1 3.31Å; E642-N645 WeakPolarHBondContact CG-ND2 3.44Å; N645-P647 VanDerWaalsContact O-CD 3.28Å; N645-P647 WeakPolarHBondContact O-CD 3.48Å
646V75.5Confident70.1Confident82 Ų8279.6 Ų79.650%0.49745%0.452SS..  trans-59.6118.2161177.40000107I644 F648 I651I644-V646 VanDerWaalsContact C-N 3.35Å; I644-V646 PolarHBondContact O-N 3.22Å; V646-F648 PolarHBondContact O-N 3.01Å; V646-I651 HydrophobicContact CG1-CD1 3.79Å
647P84.4Confident72.2Confident12 Ų1277.2 Ų77.28%0.07842%0.423CS..  trans-78.468-17333.4-37.5000110.8L413 Y416 N645 F649 V650 I651L413-P647 HydrophobicContact CD2-CG 4.16Å; Y416-P647 HydrophobicContact CD1-CG 3.93Å; Y416-P647 HydrophobicContact CE1-CB 3.96Å; Y416-P647 HydrophobicContact CE1-CG 3.65Å; Y416-P647 HydrophobicContact CE2-CB 4.2Å; Y416-P647 HydrophobicContact CE2-CG 4.37Å; Y416-P647 HydrophobicContact CG-CG 4.41Å; N645-P647 VanDerWaalsContact O-CD 3.28Å; N645-P647 WeakPolarHBondContact O-CD 3.48Å; P647-F649 PolarHBondContact O-N 3.4Å; P647-V650 HydrophobicContact CB-CB 4.02Å; P647-V650 HydrophobicContact CB-CG2 3.95Å; P647-V650 WeakPolarHBondContact O-CB 3.4Å; P647-V650 PolarHBondContact O-N 3.43Å; P647-I651 HydrophobicContact CG-CD1 4.2Å; P647-I651 HydrophobicContact CG-CG1 4.27Å; P647-I651 WeakPolarHBondContact O-CG1 3.47Å; P647-I651 PolarHBondContact O-N 3.46Å
648F83.9Confident74.3Confident124 Ų12473.8 Ų73.854%0.54439%0.387SS..Hα-helixtrans-54-50.6-167.4178.9-99.8000113.4V646 V650 I651 L652V646-F648 PolarHBondContact O-N 3.01Å; F648-V650 VanDerWaalsContact C-N 3.32Å; F648-V650 PolarHBondContact O-N 2.88Å; F648-I651 WeakPolarHBondContact O-CB 3.44Å; F648-I651 PolarHBondContact O-N 3.3Å; F648-L652 HydrophobicContact CD1-CD1 4Å; F648-L652 HydrophobicContact CE1-CD1 3.37Å; F648-L652 HydrophobicContact CE1-CG 4.14Å; F648-L652 HydrophobicContact CZ-CD1 3.71Å; F648-L652 HydrophobicContact CZ-CG 4.19Å; F648-L652 PolarHBondContact O-N 3.19Å
649F84.8Confident76.5Confident153 Ų15371.9 Ų71.967%0.67137%0.374SS*.Hα-helixtrans-66.5-34.1179.3-70-72.4000112.8P647 L652 E653P647-F649 PolarHBondContact O-N 3.4Å; F649-L652 PolarHBondContact O-N 2.91Å; F649-E653 WeakPolarHBondContact O-CG 3.35Å; F649-E653 PolarHBondContact O-N 3.24Å
650V89.5Confident78.7Confident8 Ų865.2 Ų65.25%0.04835%0.348CS..Hα-helixtrans-67.4-40.3175.4-169.40000110.5F412 C628 R632 P647 F648 L652 E653 F654F412-V650 HydrophobicContact CE1-CG1 3.7Å; F412-V650 HydrophobicContact CZ-CG1 3.54Å; C628-V650 HydrophobicContact CB-CG1 4.21Å; R632-V650 HydrophobicContact CB-CG2 4Å; R632-V650 HydrophobicContact CG-CG2 4.37Å; P647-V650 HydrophobicContact CB-CB 4.02Å; P647-V650 HydrophobicContact CB-CG2 3.95Å; P647-V650 WeakPolarHBondContact O-CB 3.4Å; P647-V650 PolarHBondContact O-N 3.43Å; F648-V650 VanDerWaalsContact C-N 3.32Å; F648-V650 PolarHBondContact O-N 2.88Å; V650-L652 VanDerWaalsContact C-N 3.34Å; V650-E653 PolarHBondContact O-N 3.21Å; V650-F654 VanDerWaalsContact O-CB 3.27Å; V650-F654 WeakPolarHBondContact O-CB 3.4Å; V650-F654 PolarHBondContact O-N 3.26Å
651I91.9Very high81.1Confident31 Ų3160.5 Ų60.516%0.15931%0.309CS..Hα-helixtrans-62-43.3174.4-66.9164.8000110.2L409 L413 V646 P647 F648 F654 I655L409-I651 HydrophobicContact CD1-CG1 4.49Å; L409-I651 HydrophobicContact CD1-CG2 4.34Å; L409-I651 HydrophobicContact CD2-CG2 4.44Å; L413-I651 HydrophobicContact CD2-CD1 4.06Å; L413-I651 HydrophobicContact CD2-CG1 4.01Å; V646-I651 HydrophobicContact CG1-CD1 3.79Å; P647-I651 HydrophobicContact CG-CD1 4.2Å; P647-I651 HydrophobicContact CG-CG1 4.27Å; P647-I651 WeakPolarHBondContact O-CG1 3.47Å; P647-I651 PolarHBondContact O-N 3.46Å; F648-I651 WeakPolarHBondContact O-CB 3.44Å; F648-I651 PolarHBondContact O-N 3.3Å; I651-F654 WeakPolarHBondContact O-CB 3.24Å; I651-F654 PolarHBondContact O-N 2.73Å; I651-I655 HydrophobicContact CG2-CD1 3.92Å; I651-I655 VanDerWaalsContact O-CG1 3.24Å; I651-I655 WeakPolarHBondContact O-CG1 3.26Å; I651-I655 PolarHBondContact O-N 2.85Å
652L91.1Very high83.5Confident53 Ų5354 Ų5428%0.27727%0.274SS..Hα-helixtrans-62.4-48175.9-73.9-179.8000112.4F648 F649 V650 F654 I655 F656F648-L652 HydrophobicContact CD1-CD1 4Å; F648-L652 HydrophobicContact CE1-CD1 3.37Å; F648-L652 HydrophobicContact CE1-CG 4.14Å; F648-L652 HydrophobicContact CZ-CD1 3.71Å; F648-L652 HydrophobicContact CZ-CG 4.19Å; F648-L652 PolarHBondContact O-N 3.19Å; F649-L652 PolarHBondContact O-N 2.91Å; V650-L652 VanDerWaalsContact C-N 3.34Å; L652-F654 VanDerWaalsContact C-N 3.28Å; L652-F654 PolarHBondContact O-N 3.26Å; L652-I655 WeakPolarHBondContact O-CB 3.31Å; L652-I655 PolarHBondContact O-N 3.36Å; L652-F656 HydrophobicContact CB-CE2 4.24Å; L652-F656 WeakPolarHBondContact O-CD2 3.34Å; L652-F656 VanDerWaalsContact O-CG 3.32Å; L652-F656 WeakPolarHBondContact O-CG 3.48Å; L652-F656 PolarHBondContact O-N 3.48Å
653E91.5Very high85.6Confident42 Ų4254.1 Ų54.120%0.19628%0.279CS..Hα-helixtrans-60.2-39.4175.2-74.2175-161.300111.9F624 F625 R632 F649 V650 F656 Y657F624-E653 VanDerWaalsContact CZ-OE2 3.27Å; F624-E653 WeakPolarHBondContact CZ-OE2 3.38Å; F625-E653 HydrophobicContact CE1-CB 4.44Å; R632-E653 IonicContact CZ-OE1 2.68Å; R632-E653 IonicContact CZ-OE2 2.79Å; R632-E653 IonicContact NH1-OE1 2.95Å; R632-E653 PolarHBondContact NH1-OE1 2.97Å; R632-E653 IonicContact NH1-OE2 2.82Å; R632-E653 PolarHBondContact NH1-OE2 2.99Å; R632-E653 VanDerWaalsContact NH2-CD 3.3Å; R632-E653 IonicContact NH2-OE1 3.34Å; R632-E653 PolarHBondContact NH2-OE1 2.76Å; R632-E653 IonicContact NH2-OE2 3.1Å; R632-E653 PolarHBondContact NH2-OE2 3.32Å; F649-E653 WeakPolarHBondContact O-CG 3.35Å; F649-E653 PolarHBondContact O-N 3.24Å; V650-E653 PolarHBondContact O-N 3.21Å; E653-F656 PolarHBondContact O-N 2.59Å; E653-Y657 HydrophobicContact CB-CD2 4.38Å; E653-Y657 HydrophobicContact CB-CE2 4.26Å; E653-Y657 HydrophobicContact CG-CE2 4.4Å; E653-Y657 PolarHBondContact O-N 2.82Å
654F94.4Very high87.7Confident6 Ų648.4 Ų48.43%0.02624%0.239CC..Hα-helixtrans-59-49.4173.7-163.4-77.7000111D408 L409 F412 F625 V650 I651 L652 F656 I658D408-F654 VanDerWaalsContact C-CZ 3.48Å; D408-F654 HydrophobicContact CB-CE1 4.03Å; D408-F654 HydrophobicContact CB-CZ 3.84Å; D408-F654 WeakPolarHBondContact O-CZ 3.19Å; L409-F654 HydrophobicContact CB-CD1 4.05Å; L409-F654 HydrophobicContact CB-CE1 3.79Å; L409-F654 HydrophobicContact CD1-CB 4.3Å; L409-F654 HydrophobicContact CD1-CD1 3.75Å; L409-F654 HydrophobicContact CD1-CE1 4.22Å; L409-F654 HydrophobicContact CD1-CG 3.98Å; L409-F654 HydrophobicContact CG-CD1 4.47Å; F412-F654 HydrophobicContact CB-CD2 4.13Å; F412-F654 HydrophobicContact CB-CE2 3.48Å; F412-F654 VanDerWaalsContact CB-CE2 3.48Å; F412-F654 HydrophobicContact CB-CZ 3.93Å; F412-F654 AromaticContact CD1-CD2 3.99Å; F412-F654 HydrophobicContact CD1-CD2 3.99Å; F412-F654 HydrophobicContact CD1-CE2 4.22Å; F412-F654 AromaticContact CD2-CD2 3.92Å; F412-F654 HydrophobicContact CD2-CD2 3.92Å; F412-F654 AromaticContact CD2-CE2 3.67Å; F412-F654 HydrophobicContact CD2-CE2 3.67Å; F412-F654 HydrophobicContact CE1-CD2 4.44Å; F412-F654 HydrophobicContact CE2-CD2 4.35Å; F412-F654 HydrophobicContact CE2-CE2 4.48Å; F412-F654 AromaticContact CG-CD2 3.73Å; F412-F654 HydrophobicContact CG-CD2 3.73Å; F412-F654 AromaticContact CG-CE2 3.51Å; F412-F654 HydrophobicContact CG-CE2 3.51Å; F412-F654 HydrophobicContact CG-CZ 4.41Å; F625-F654 HydrophobicContact CD1-CB 4.43Å; F625-F654 AromaticContact CD1-CD2 3.56Å; F625-F654 HydrophobicContact CD1-CD2 3.56Å; F625-F654 HydrophobicContact CD1-CE2 4.29Å; F625-F654 HydrophobicContact CD1-CG 4.42Å; F625-F654 HydrophobicContact CD2-CD2 4.28Å; F625-F654 VanDerWaalsContact CE1-CA 3.49Å; F625-F654 HydrophobicContact CE1-CB 3.75Å; F625-F654 AromaticContact CE1-CD2 3.71Å; F625-F654 HydrophobicContact CE1-CD2 3.71Å; F625-F654 HydrophobicContact CE1-CG 4.13Å; F625-F654 HydrophobicContact CE2-CD2 4.41Å; F625-F654 AromaticContact CG-CD2 3.89Å; F625-F654 HydrophobicContact CG-CD2 3.89Å; F625-F654 HydrophobicContact CG-CE2 4.2Å; F625-F654 HydrophobicContact CZ-CB 4.07Å; F625-F654 HydrophobicContact CZ-CD2 4.17Å; F625-F654 HydrophobicContact CZ-CG 4.37Å; V650-F654 VanDerWaalsContact O-CB 3.27Å; V650-F654 WeakPolarHBondContact O-CB 3.4Å; V650-F654 PolarHBondContact O-N 3.26Å; I651-F654 WeakPolarHBondContact O-CB 3.24Å; I651-F654 PolarHBondContact O-N 2.73Å; L652-F654 VanDerWaalsContact C-N 3.28Å; L652-F654 PolarHBondContact O-N 3.26Å; F654-F656 VanDerWaalsContact C-N 3.26Å; F654-F656 PolarHBondContact O-N 2.96Å; F654-I658 HydrophobicContact CD1-CB 3.96Å; F654-I658 HydrophobicContact CD1-CG1 3.95Å; F654-I658 HydrophobicContact CD1-CG2 4.44Å; F654-I658 HydrophobicContact CD2-CG1 4.05Å; F654-I658 HydrophobicContact CE1-CB 3.81Å; F654-I658 HydrophobicContact CE1-CG1 3.75Å; F654-I658 HydrophobicContact CE1-CG2 3.84Å; F654-I658 HydrophobicContact CE2-CG1 3.84Å; F654-I658 HydrophobicContact CG-CG1 4.1Å; F654-I658 HydrophobicContact CZ-CB 4.24Å; F654-I658 HydrophobicContact CZ-CD1 4.4Å; F654-I658 HydrophobicContact CZ-CG1 3.69Å; F654-I658 HydrophobicContact CZ-CG2 4.24Å; F654-I658 WeakPolarHBondContact O-CA 3.46Å; F654-I658 VanDerWaalsContact O-CB 3.23Å; F654-I658 WeakPolarHBondContact O-CB 3.21Å; F654-I658 PolarHBondContact O-N 3.11Å
655I93.9Very high89.6Confident28 Ų2842 Ų4214%0.14421%0.206CC..Hα-helixtrans-56.9-41.9176.1-67.2162.2000110.8V401 I405 I651 L652 G659V401-I655 HydrophobicContact CG1-CG2 4.29Å; I405-I655 HydrophobicContact CD1-CB 4.08Å; I405-I655 HydrophobicContact CD1-CG1 3.69Å; I405-I655 HydrophobicContact CD1-CG2 4.18Å; I651-I655 HydrophobicContact CG2-CD1 3.92Å; I651-I655 VanDerWaalsContact O-CG1 3.24Å; I651-I655 WeakPolarHBondContact O-CG1 3.26Å; I651-I655 PolarHBondContact O-N 2.85Å; L652-I655 WeakPolarHBondContact O-CB 3.31Å; L652-I655 PolarHBondContact O-N 3.36Å; I655-G659 WeakPolarHBondContact O-CA 3.31Å; I655-G659 PolarHBondContact O-N 3.44Å
656F92.4Very high90.7Very high121 Ų12140.1 Ų40.153%0.53120%0.196SC..Hα-helixtrans-73.9-52.7-178.6-60.9-36000113.3L652 E653 F654 L660L652-F656 HydrophobicContact CB-CE2 4.24Å; L652-F656 WeakPolarHBondContact O-CD2 3.34Å; L652-F656 VanDerWaalsContact O-CG 3.32Å; L652-F656 WeakPolarHBondContact O-CG 3.48Å; L652-F656 PolarHBondContact O-N 3.48Å; E653-F656 PolarHBondContact O-N 2.59Å; F654-F656 VanDerWaalsContact C-N 3.26Å; F654-F656 PolarHBondContact O-N 2.96Å; F656-L660 VanDerWaalsContact O-CB 3.27Å; F656-L660 WeakPolarHBondContact O-CB 3.21Å; F656-L660 VanDerWaalsContact O-CG 3.26Å; F656-L660 WeakPolarHBondContact O-CG 3.29Å; F656-L660 PolarHBondContact O-N 3.32Å
657Y94.6Very high91.5Very high49 Ų4937.6 Ų37.619%0.19218%0.18CC..Hα-helixtrans-79.6-45.4-173.1-59.5-27.6000112.7I451 T452 L455 F624 F625 E653 G659 L661I451-Y657 HydrophobicContact CD1-CD2 4.45Å; I451-Y657 HydrophobicContact CG2-CD1 4.31Å; I451-Y657 HydrophobicContact CG2-CD2 4.3Å; I451-Y657 HydrophobicContact CG2-CG 4.08Å; T452-Y657 HydrophobicContact CG2-CE1 3.84Å; T452-Y657 WeakPolarHBondContact CG2-OH 3.42Å; L455-Y657 HydrophobicContact CD2-CD1 4.39Å; L455-Y657 WeakPolarHBondContact CD2-O 3.33Å; F624-Y657 HydrophobicContact CD1-CD2 4.12Å; F624-Y657 HydrophobicContact CD1-CE2 4.48Å; F624-Y657 AromaticContact CE1-CD2 3.66Å; F624-Y657 HydrophobicContact CE1-CD2 3.66Å; F624-Y657 AromaticContact CE1-CE2 3.72Å; F624-Y657 HydrophobicContact CE1-CE2 3.72Å; F624-Y657 HydrophobicContact CZ-CD2 4.18Å; F624-Y657 AromaticContact CZ-CE2 3.75Å; F624-Y657 HydrophobicContact CZ-CE2 3.75Å; F625-Y657 HydrophobicContact CE2-CD2 4.27Å; F625-Y657 AromaticContact CZ-CD2 3.89Å; F625-Y657 HydrophobicContact CZ-CD2 3.89Å; F625-Y657 HydrophobicContact CZ-CG 4.4Å; E653-Y657 HydrophobicContact CB-CD2 4.38Å; E653-Y657 HydrophobicContact CB-CE2 4.26Å; E653-Y657 HydrophobicContact CG-CE2 4.4Å; E653-Y657 PolarHBondContact O-N 2.82Å; Y657-G659 VanDerWaalsContact C-N 3.3Å; Y657-L661 WeakPolarHBondContact O-CB 3.35Å; Y657-L661 PolarHBondContact O-N 3.37Å
658I94.7Very high91.7Very high1 Ų137.4 Ų37.41%0.00518%0.178CC..Hα-helixtrans-69-36.4172.7-62.3-74.1000109.4I405 D408 V621 Y622 F625 F654 L661 K662I405-I658 HydrophobicContact CB-CG2 4.34Å; I405-I658 HydrophobicContact CG2-CG2 3.91Å; D408-I658 HydrophobicContact CB-CG2 4.35Å; V621-I658 HydrophobicContact CG1-CD1 3.53Å; V621-I658 HydrophobicContact CG1-CG1 4.27Å; Y622-I658 HydrophobicContact CE1-CD1 4.44Å; F625-I658 HydrophobicContact CD2-CD1 3.87Å; F625-I658 HydrophobicContact CD2-CG1 3.79Å; F625-I658 HydrophobicContact CE2-CD1 4.05Å; F625-I658 HydrophobicContact CE2-CG1 3.59Å; F625-I658 HydrophobicContact CZ-CG1 4.36Å; F654-I658 HydrophobicContact CD1-CB 3.96Å; F654-I658 HydrophobicContact CD1-CG1 3.95Å; F654-I658 HydrophobicContact CD1-CG2 4.44Å; F654-I658 HydrophobicContact CD2-CG1 4.05Å; F654-I658 HydrophobicContact CE1-CB 3.81Å; F654-I658 HydrophobicContact CE1-CG1 3.75Å; F654-I658 HydrophobicContact CE1-CG2 3.84Å; F654-I658 HydrophobicContact CE2-CG1 3.84Å; F654-I658 HydrophobicContact CG-CG1 4.1Å; F654-I658 HydrophobicContact CZ-CB 4.24Å; F654-I658 HydrophobicContact CZ-CD1 4.4Å; F654-I658 HydrophobicContact CZ-CG1 3.69Å; F654-I658 HydrophobicContact CZ-CG2 4.24Å; F654-I658 WeakPolarHBondContact O-CA 3.46Å; F654-I658 VanDerWaalsContact O-CB 3.23Å; F654-I658 WeakPolarHBondContact O-CB 3.21Å; F654-I658 PolarHBondContact O-N 3.11Å; I658-L661 PolarHBondContact O-N 3.36Å; I658-K662 HydrophobicContact CG2-CG 4.02Å; I658-K662 WeakPolarHBondContact O-CB 3.34Å; I658-K662 WeakPolarHBondContact O-CG 3.43Å; I658-K662 PolarHBondContact O-N 2.99Å
659G93.5Very high91.9Very high2 Ų231.7 Ų31.72%0.02115%0.153CC..Hα-helixtrans-57.9-51.417400000112.8V401 I655 Y657 L661 K662 V663V401-G659 VanDerWaalsContact CG2-CA 3.42Å; I655-G659 WeakPolarHBondContact O-CA 3.31Å; I655-G659 PolarHBondContact O-N 3.44Å; Y657-G659 VanDerWaalsContact C-N 3.3Å; G659-L661 PolarHBondContact O-N 2.96Å; G659-K662 PolarHBondContact O-N 3.48Å; G659-V663 VanDerWaalsContact O-CG2 3.3Å; G659-V663 WeakPolarHBondContact O-CG2 3.3Å; G659-V663 PolarHBondContact O-N 2.87Å
660L94.8Very high92.2Very high69 Ų6924.4 Ų24.436%0.36112%0.121SC..Hα-helixtrans-62.8-39.2176.5-79.6172.4000112.6L455 V459 F656 K662 V663 A664L455-L660 HydrophobicContact CD1-CB 4.39Å; L455-L660 HydrophobicContact CD2-CB 3.6Å; L455-L660 HydrophobicContact CD2-CD1 4.18Å; L455-L660 HydrophobicContact CG-CB 3.93Å; V459-L660 HydrophobicContact CG2-CB 4.32Å; V459-L660 HydrophobicContact CG2-CD2 4.47Å; F656-L660 VanDerWaalsContact O-CB 3.27Å; F656-L660 WeakPolarHBondContact O-CB 3.21Å; F656-L660 VanDerWaalsContact O-CG 3.26Å; F656-L660 WeakPolarHBondContact O-CG 3.29Å; F656-L660 PolarHBondContact O-N 3.32Å; L660-K662 VanDerWaalsContact C-N 3.34Å; L660-K662 PolarHBondContact O-N 2.97Å; L660-V663 PolarHBondContact O-N 2.73Å; L660-A664 PolarHBondContact O-N 2.75Å
661L95.4Very high92.1Very high1 Ų124.2 Ų24.21%0.00512%0.12CC..Hα-helixtrans-62.1-42.8175-176.366.3000111.4F17 L455 V617 V621 Y622 Y657 I658 G659 A664 Q665F17-L661 HydrophobicContact CD2-CD1 3.84Å; F17-L661 HydrophobicContact CD2-CD2 4.38Å; F17-L661 HydrophobicContact CD2-CG 4Å; F17-L661 HydrophobicContact CE2-CD1 3.79Å; F17-L661 HydrophobicContact CE2-CG 4.21Å; L455-L661 HydrophobicContact CD1-CB 4.1Å; L455-L661 HydrophobicContact CD1-CD1 4.15Å; V617-L661 HydrophobicContact CG1-CD1 3.92Å; V621-L661 HydrophobicContact CB-CD2 3.99Å; V621-L661 HydrophobicContact CG1-CD2 3.94Å; V621-L661 HydrophobicContact CG2-CD2 4.31Å; Y622-L661 HydrophobicContact CD2-CD2 4.3Å; Y622-L661 HydrophobicContact CE2-CD2 3.88Å; Y657-L661 WeakPolarHBondContact O-CB 3.35Å; Y657-L661 PolarHBondContact O-N 3.37Å; I658-L661 PolarHBondContact O-N 3.36Å; G659-L661 PolarHBondContact O-N 2.96Å; L661-A664 PolarHBondContact O-N 3Å; L661-Q665 PolarHBondContact O-N 2.66Å
662K92.7Very high91.7Very high1 Ų122.8 Ų22.80%0.00411%0.113CC..Hα-helixtrans-69.4-36176.8-66.1-73.6-175.7171.40111.9V12 I404 I405 D408 I658 G659 L660 A664 Q665 V666V12-K662 HydrophobicContact CG1-CD 3.8Å; I404-K662 HydrophobicContact CB-CB 4.41Å; I404-K662 HydrophobicContact CD1-CB 3.58Å; I404-K662 HydrophobicContact CG1-CB 3.94Å; I405-K662 HydrophobicContact CG2-CG 4.13Å; D408-K662 VanDerWaalsContact CG-NZ 3.3Å; D408-K662 WeakPolarHBondContact OD1-CE 3.13Å; D408-K662 IonicContact OD1-NZ 2.72Å; D408-K662 PolarHBondContact OD1-NZ 3.11Å; D408-K662 VanDerWaalsContact OD2-CE 3.25Å; D408-K662 WeakPolarHBondContact OD2-CE 2.99Å; D408-K662 IonicContact OD2-NZ 2.78Å; D408-K662 PolarHBondContact OD2-NZ 3.26Å; I658-K662 HydrophobicContact CG2-CG 4.02Å; I658-K662 WeakPolarHBondContact O-CB 3.34Å; I658-K662 WeakPolarHBondContact O-CG 3.43Å; I658-K662 PolarHBondContact O-N 2.99Å; G659-K662 PolarHBondContact O-N 3.48Å; L660-K662 VanDerWaalsContact C-N 3.34Å; L660-K662 PolarHBondContact O-N 2.97Å; K662-A664 VanDerWaalsContact C-N 3.35Å; K662-Q665 WeakPolarHBondContact O-CB 3.36Å; K662-Q665 PolarHBondContact O-N 3.45Å; K662-Q665 VanDerWaalsContact O-N 3.14Å; K662-V666 WeakPolarHBondContact O-CG2 3.26Å; K662-V666 PolarHBondContact O-N 2.82Å
663V92.2Very high91.2Very high54 Ų5422.6 Ų22.633%0.32711%0.11SC..Hα-helixtrans-58.8-48.3170.8168.10000109.9G659 L660 Q665 V666 L667G659-V663 VanDerWaalsContact O-CG2 3.3Å; G659-V663 WeakPolarHBondContact O-CG2 3.3Å; G659-V663 PolarHBondContact O-N 2.87Å; L660-V663 PolarHBondContact O-N 2.73Å; V663-Q665 VanDerWaalsContact C-N 3.26Å; V663-Q665 PolarHBondContact O-N 2.96Å; V663-V666 PolarHBondContact O-N 3.36Å; V663-L667 HydrophobicContact CG1-CD1 3.87Å; V663-L667 HydrophobicContact CG1-CG 4.33Å; V663-L667 VanDerWaalsContact O-CG 3.28Å; V663-L667 WeakPolarHBondContact O-CG 3.27Å; V663-L667 PolarHBondContact O-N 3.3Å
664A93.1Very high90.8Very high0 Ų021.6 Ų21.60%011%0.106CC..Hα-helixtrans-59.9-38.1174.700000112.1F458 V459 V462 L660 L661 K662 L667 L668F458-A664 HydrophobicContact CD1-CB 3.76Å; F458-A664 HydrophobicContact CE1-CB 3.56Å; V459-A664 HydrophobicContact CG2-CB 3.96Å; V462-A664 WeakPolarHBondContact CG1-O 3.41Å; L660-A664 PolarHBondContact O-N 2.75Å; L661-A664 PolarHBondContact O-N 3Å; K662-A664 VanDerWaalsContact C-N 3.35Å; A664-L667 PolarHBondContact O-N 2.92Å; A664-L668 WeakPolarHBondContact O-CB 3.44Å; A664-L668 PolarHBondContact O-N 2.85Å
665Q90.9Very high90.1Very high1 Ų122.1 Ų22.11%0.00511%0.109CC..Hα-helixtrans-60.3-47.8175.3-176.3-178-15.300112.7V12 F17 L661 K662 V663 L668V12-Q665 HydrophobicContact CG2-CB 4.24Å; V12-Q665 HydrophobicContact CG2-CG 3.81Å; F17-Q665 HydrophobicContact CD1-CB 4.26Å; F17-Q665 HydrophobicContact CD1-CG 3.76Å; F17-Q665 HydrophobicContact CD2-CB 4.49Å; F17-Q665 HydrophobicContact CE1-CB 3.69Å; F17-Q665 HydrophobicContact CE1-CG 3.4Å; F17-Q665 HydrophobicContact CE2-CB 3.92Å; F17-Q665 HydrophobicContact CE2-CG 4.46Å; F17-Q665 HydrophobicContact CG-CG 4.48Å; F17-Q665 HydrophobicContact CZ-CB 3.49Å; F17-Q665 VanDerWaalsContact CZ-CB 3.49Å; F17-Q665 HydrophobicContact CZ-CG 3.79Å; L661-Q665 PolarHBondContact O-N 2.66Å; K662-Q665 WeakPolarHBondContact O-CB 3.36Å; K662-Q665 PolarHBondContact O-N 3.45Å; K662-Q665 VanDerWaalsContact O-N 3.14Å; V663-Q665 VanDerWaalsContact C-N 3.26Å; V663-Q665 PolarHBondContact O-N 2.96Å; Q665-L668 PolarHBondContact O-N 3.17Å
666V89.2Confident89.6Confident4 Ų423.3 Ų23.32%0.02412%0.116CC..Hα-helixtrans-58.9-49.2175.8178.20000110.1V12 K662 V663 L668 N669 D674 D676V12-V666 HydrophobicContact CB-CG2 4.3Å; V12-V666 HydrophobicContact CG2-CB 4.18Å; V12-V666 HydrophobicContact CG2-CG2 3.34Å; K662-V666 WeakPolarHBondContact O-CG2 3.26Å; K662-V666 PolarHBondContact O-N 2.82Å; V663-V666 PolarHBondContact O-N 3.36Å; V666-L668 PolarHBondContact O-N 3.31Å; V666-N669 CarbonylContact O-C 3.46Å; V666-N669 PolarHBondContact O-N 3.01Å; V666-D674 HydrophobicContact CG1-CB 4.22Å; V666-D676 HydrophobicContact CG1-CB 3.88Å
667L92.3Very high89.3Confident29 Ų2917.6 Ų17.615%0.1529%0.091CC..Hα-helixtrans-68.8-20.5-175.7-63.8179000113.5V462 A463 W466 V663 A664V462-L667 HydrophobicContact CG1-CB 3.63Å; A463-L667 HydrophobicContact CB-CD1 4.13Å; W466-L667 HydrophobicContact CB-CB 4.23Å; W466-L667 HydrophobicContact CB-CD2 4.38Å; W466-L667 HydrophobicContact CD2-CD2 3.85Å; W466-L667 HydrophobicContact CG-CB 4.25Å; W466-L667 HydrophobicContact CG-CD2 3.7Å; V663-L667 HydrophobicContact CG1-CD1 3.87Å; V663-L667 HydrophobicContact CG1-CG 4.33Å; V663-L667 VanDerWaalsContact O-CG 3.28Å; V663-L667 WeakPolarHBondContact O-CG 3.27Å; V663-L667 PolarHBondContact O-N 3.3Å; A664-L667 PolarHBondContact O-N 2.92Å
668L89.8Confident89Confident8 Ų816 Ų164%0.0429%0.085CC..Hα-helixtrans-69.1-34.4-178.4-166.2144.8000112.1Y5 C9 F17 F458 V462 V609 A664 Q665 V666Y5-L668 HydrophobicContact CD2-CD2 4.27Å; Y5-L668 HydrophobicContact CE2-CD1 4Å; Y5-L668 HydrophobicContact CE2-CD2 3.51Å; Y5-L668 HydrophobicContact CE2-CG 4.42Å; C9-L668 HydrophobicContact CB-CD2 4.13Å; F17-L668 HydrophobicContact CZ-CD1 4.49Å; F458-L668 HydrophobicContact CZ-CD1 4.29Å; V462-L668 HydrophobicContact CG1-CB 4.18Å; V609-L668 HydrophobicContact CB-CD1 4.44Å; A664-L668 WeakPolarHBondContact O-CB 3.44Å; A664-L668 PolarHBondContact O-N 2.85Å; Q665-L668 PolarHBondContact O-N 3.17Å; V666-L668 PolarHBondContact O-N 3.31Å
669N88.3Confident88.4Confident4 Ų417.1 Ų17.12%0.0219%0.09CC..  trans-128.186.7173.8-176.33.8000111.6T6 C9 A10 V666 F671 G672T6-N669 HydrophobicContact CG2-CB 3.94Å; T6-N669 PolarHBondContact O-ND2 3.04Å; C9-N669 HydrophobicContact CB-CB 4.03Å; A10-N669 VanDerWaalsContact CA-ND2 3.27Å; A10-N669 WeakPolarHBondContact CA-ND2 3.09Å; A10-N669 PolarHBondContact N-ND2 3.06Å; V666-N669 CarbonylContact O-C 3.46Å; V666-N669 PolarHBondContact O-N 3.01Å; N669-F671 PolarHBondContact O-N 2.74Å; N669-F671 VanDerWaalsContact O-N 3.12Å; N669-F671 PolarHBondContact OD1-N 2.7Å; N669-F671 VanDerWaalsContact OD1-N 3.1Å; N669-G672 PolarHBondContact O-N 3.41Å
670P90.6Very high88.1Confident1 Ų117.1 Ų17.11%0.0069%0.09CC..THydrogen-bonded Turntrans-75.63-179.833.8-38.4000115I469 D677 F678I469-P670 HydrophobicContact CB-CG 4.36Å; I469-P670 HydrophobicContact CD1-CG 3.92Å; I469-P670 HydrophobicContact CG2-CG 3.92Å; P670-D677 VanDerWaalsContact CA-OD1 3.29Å; P670-D677 WeakPolarHBondContact CA-OD1 3.39Å; P670-D677 WeakPolarHBondContact O-CB 3.4Å; P670-F678 HydrophobicContact CB-CD2 3.66Å; P670-F678 HydrophobicContact CB-CE1 4.34Å; P670-F678 HydrophobicContact CB-CE2 3.35Å; P670-F678 HydrophobicContact CB-CG 4.28Å; P670-F678 HydrophobicContact CB-CZ 3.7Å; P670-F678 HydrophobicContact CG-CD2 4.06Å; P670-F678 HydrophobicContact CG-CE2 3.54Å; P670-F678 HydrophobicContact CG-CZ 4.17Å; P670-F678 PolarHBondContact O-N 3.45Å
671F88.1Confident87.6Confident4 Ų414.1 Ų14.12%0.0187%0.074CC..THydrogen-bonded Turntrans-102.210.4-179.5-58.5-53.5000112.9I469 I516 S517 T518 L601 N669 F678 L680I469-F671 HydrophobicContact CG2-CE1 3.92Å; I469-F671 HydrophobicContact CG2-CE2 3.7Å; I469-F671 HydrophobicContact CG2-CZ 3.2Å; I516-F671 HydrophobicContact CB-CD2 4.41Å; I516-F671 HydrophobicContact CD1-CD2 3.94Å; I516-F671 HydrophobicContact CD1-CE1 4.19Å; I516-F671 HydrophobicContact CD1-CE2 3.54Å; I516-F671 HydrophobicContact CD1-CG 4.42Å; I516-F671 HydrophobicContact CD1-CZ 3.65Å; I516-F671 HydrophobicContact CG1-CD2 4.01Å; I516-F671 HydrophobicContact CG1-CE2 4.14Å; I516-F671 HydrophobicContact CG1-CG 4.27Å; I516-F671 HydrophobicContact CG1-CZ 4.48Å; I516-F671 WeakPolarHBondContact O-CB 3.32Å; S517-F671 WeakPolarHBondContact CA-O 3.13Å; S517-F671 WeakPolarHBondContact CB-O 3.14Å; S517-F671 PolarHBondContact OG-O 2.9Å; T518-F671 PolarHBondContact N-O 2.98Å; L601-F671 HydrophobicContact CD1-CZ 3.69Å; L601-F671 HydrophobicContact CD2-CZ 4.33Å; L601-F671 HydrophobicContact CG-CZ 4.03Å; N669-F671 PolarHBondContact O-N 2.74Å; N669-F671 VanDerWaalsContact O-N 3.12Å; N669-F671 PolarHBondContact OD1-N 2.7Å; N669-F671 VanDerWaalsContact OD1-N 3.1Å; F671-F678 HydrophobicContact CD1-CD2 4.16Å; F671-F678 AromaticContact CE1-CD2 3.95Å; F671-F678 HydrophobicContact CE1-CD2 3.95Å; F671-F678 HydrophobicContact CE1-CE2 4.49Å; F671-L680 HydrophobicContact CD1-CD1 3.56Å; F671-L680 HydrophobicContact CD1-CG 4.39Å; F671-L680 HydrophobicContact CE1-CD1 4.14Å; F671-L680 HydrophobicContact CG-CD1 4.45Å
672G82.7Confident87.1Confident1 Ų116.1 Ų16.11%0.018%0.082CC..SBendtrans-77-147.2-18000000114.6A10 N669 D677A10-G672 CarbonylContact O-C 3.26Å; A10-G672 WeakPolarHBondContact O-CA 3.39Å; N669-G672 PolarHBondContact O-N 3.41Å; G672-D677 WeakPolarHBondContact CA-OD2 3.28Å; G672-D677 PolarHBondContact N-OD2 3.45Å
673E79.4Confident86.9Confident49 Ų4916.7 Ų16.723%0.2299%0.085CC..SBendtrans-129.717.7178.1-61.4171.7-122.900113.7A10 T11 T518 A519 K522 D677A10-E673 PolarHBondContact O-N 3.4Å; T11-E673 HydrophobicContact CG2-CB 3.88Å; T518-E673 PolarHBondContact OG1-OE1 3.15Å; A519-E673 HydrophobicContact CB-CG 4.1Å; K522-E673 VanDerWaalsContact CE-OE1 3.24Å; K522-E673 WeakPolarHBondContact CE-OE1 3.11Å; K522-E673 IonicContact NZ-OE1 2.65Å; K522-E673 PolarHBondContact NZ-OE1 2.95Å; K522-E673 IonicContact NZ-OE2 3.58Å; K522-E673 PolarHBondContact NZ-OE2 2.64Å; E673-D677 PolarHBondContact N-OD2 3.11Å
674D83.6Confident86.8Confident21 Ų2114.5 Ų14.511%0.1127%0.071CC..SBendtrans-70.6166.2172.4-67.9-49.6000111.7T11 V12 V666 D676 D677T11-D674 WeakPolarHBondContact CA-OD2 3.24Å; V12-D674 WeakPolarHBondContact CG2-OD2 3.36Å; V12-D674 PolarHBondContact N-OD1 2.82Å; V12-D674 PolarHBondContact N-OD2 3.01Å; V666-D674 HydrophobicContact CG1-CB 4.22Å; D674-D676 PolarHBondContact O-N 2.88Å; D674-D677 WeakPolarHBondContact CB-OD2 3.48Å; D674-D677 PolarHBondContact N-OD2 2.7Å; D674-D677 PolarHBondContact O-N 3.32Å
675D80.3Confident86.5Confident16 Ų1615.3 Ų15.39%0.0868%0.075CC..THydrogen-bonded Turntrans-62.7-32.9-178.8-72.1-38000111.5M374 T375 R398 G399 K403M374-D675 CarbonylContact C-O 3.59Å; M374-D675 CarbonylContact O-C 3.55Å; T375-D675 WeakPolarHBondContact CA-O 3.35Å; T375-D675 PolarHBondContact N-O 3.36Å; R398-D675 HydrophobicContact CG-CB 4.38Å; R398-D675 VanDerWaalsContact CG-CG 3.43Å; R398-D675 WeakPolarHBondContact CG-OD1 3.49Å; R398-D675 WeakPolarHBondContact CG-OD2 3.48Å; R398-D675 IonicContact CZ-OD1 3.57Å; R398-D675 IonicContact NE-OD1 3.69Å; R398-D675 PolarHBondContact NE-OD1 3.35Å; R398-D675 IonicContact NH2-OD1 3.59Å; G399-D675 PolarHBondContact N-OD2 2.85Å; K403-D675 VanDerWaalsContact NZ-CG 3.29Å; K403-D675 IonicContact NZ-OD1 3.1Å; K403-D675 PolarHBondContact NZ-OD1 3.48Å; K403-D675 IonicContact NZ-OD2 2.71Å; K403-D675 PolarHBondContact NZ-OD2 3.48Å
676D82.8Confident86.4Confident54 Ų5417.8 Ų17.829%0.2899%0.085SC..THydrogen-bonded Turntrans-93.72.7-174.9-53.1-71.4000114V666 D674V666-D676 HydrophobicContact CG1-CB 3.88Å; D674-D676 PolarHBondContact O-N 2.88Å
677D85.8Confident86.6Confident0 Ų017.8 Ų17.80%09%0.085CC..SBendtrans-71.2157.4-179.8-73-24.3000112.9T375 P670 G672 E673 D674 E679T375-D677 PolarHBondContact OG1-O 3.03Å; P670-D677 VanDerWaalsContact CA-OD1 3.29Å; P670-D677 WeakPolarHBondContact CA-OD1 3.39Å; P670-D677 WeakPolarHBondContact O-CB 3.4Å; G672-D677 WeakPolarHBondContact CA-OD2 3.28Å; G672-D677 PolarHBondContact N-OD2 3.45Å; E673-D677 PolarHBondContact N-OD2 3.11Å; D674-D677 WeakPolarHBondContact CB-OD2 3.48Å; D674-D677 PolarHBondContact N-OD2 2.7Å; D674-D677 PolarHBondContact O-N 3.32Å; D677-E679 PolarHBondContact O-N 3.23Å
678F88.7Confident86.5Confident17 Ų1716.4 Ų16.48%0.0758%0.077CC..  trans-68.2130.2-178.9-58.6-36.4000111.3W466 I469 F470 I473 P670 F671 L680W466-F678 HydrophobicContact CD2-CE1 4.37Å; W466-F678 HydrophobicContact CD2-CZ 4.11Å; W466-F678 AromaticContact CE2-CE1 3.55Å; W466-F678 AromaticContact CE2-CZ 3.63Å; W466-F678 HydrophobicContact CG-CZ 4.47Å; W466-F678 AromaticContact CH2-CE1 3.95Å; W466-F678 HydrophobicContact CH2-CE1 3.95Å; W466-F678 HydrophobicContact CZ2-CD1 4.26Å; W466-F678 AromaticContact CZ2-CE1 3.31Å; W466-F678 HydrophobicContact CZ2-CE1 3.31Å; W466-F678 AromaticContact CZ2-CZ 3.89Å; W466-F678 HydrophobicContact CZ2-CZ 3.89Å; W466-F678 AromaticContact NE1-CE1 3.89Å; W466-F678 AromaticContact NE1-CZ 3.75Å; I469-F678 HydrophobicContact CB-CE2 4.32Å; I469-F678 HydrophobicContact CG2-CE2 3.8Å; F470-F678 HydrophobicContact CB-CE1 3.89Å; F470-F678 HydrophobicContact CB-CE2 4.17Å; F470-F678 HydrophobicContact CB-CZ 3.5Å; F470-F678 VanDerWaalsContact CB-CZ 3.5Å; F470-F678 AromaticContact CD2-CD1 3.88Å; F470-F678 HydrophobicContact CD2-CD1 3.88Å; F470-F678 AromaticContact CD2-CE1 3.54Å; F470-F678 HydrophobicContact CD2-CE1 3.54Å; F470-F678 AromaticContact CD2-CZ 3.96Å; F470-F678 HydrophobicContact CD2-CZ 3.96Å; F470-F678 HydrophobicContact CE2-CE1 4.5Å; F470-F678 HydrophobicContact CG-CE1 4.1Å; F470-F678 HydrophobicContact CG-CZ 4.19Å; I473-F678 HydrophobicContact CD1-CB 4.29Å; I473-F678 HydrophobicContact CD1-CD2 3.63Å; I473-F678 HydrophobicContact CD1-CE2 4.13Å; I473-F678 HydrophobicContact CD1-CG 3.98Å; P670-F678 HydrophobicContact CB-CD2 3.66Å; P670-F678 HydrophobicContact CB-CE1 4.34Å; P670-F678 HydrophobicContact CB-CE2 3.35Å; P670-F678 HydrophobicContact CB-CG 4.28Å; P670-F678 HydrophobicContact CB-CZ 3.7Å; P670-F678 HydrophobicContact CG-CD2 4.06Å; P670-F678 HydrophobicContact CG-CE2 3.54Å; P670-F678 HydrophobicContact CG-CZ 4.17Å; P670-F678 PolarHBondContact O-N 3.45Å; F671-F678 HydrophobicContact CD1-CD2 4.16Å; F671-F678 AromaticContact CE1-CD2 3.95Å; F671-F678 HydrophobicContact CE1-CD2 3.95Å; F671-F678 HydrophobicContact CE1-CE2 4.49Å; F678-L680 HydrophobicContact CB-CD2 4.1Å; F678-L680 HydrophobicContact CB-CG 4.22Å; F678-L680 PolarHBondContact O-N 2.86Å
679E81.7Confident86.5Confident23 Ų2318 Ų1811%0.1079%0.085CC..  trans-75.861.2179.5-66.6-79.9-156.900112.1R356 M374 T375 D677 N681 Y682 I683R356-E679 WeakPolarHBondContact CD-OE1 3.22Å; R356-E679 VanDerWaalsContact CG-OE2 3.28Å; R356-E679 WeakPolarHBondContact CG-OE2 3.43Å; R356-E679 IonicContact NE-OE1 3.74Å; R356-E679 PolarHBondContact NE-OE1 2.99Å; R356-E679 VanDerWaalsContact NE-OE1 3.14Å; R356-E679 IonicContact NE-OE2 2.93Å; R356-E679 PolarHBondContact NE-OE2 3.19Å; R356-E679 VanDerWaalsContact NE-OE2 3.13Å; M374-E679 WeakPolarHBondContact CA-OE1 3.15Å; M374-E679 WeakPolarHBondContact CB-OE1 3.32Å; M374-E679 WeakPolarHBondContact CG-OE1 3.5Å; M374-E679 PolarHBondContact N-OE1 2.89Å; T375-E679 PolarHBondContact N-OE1 2.79Å; T375-E679 WeakPolarHBondContact OG1-CG 3.46Å; D677-E679 PolarHBondContact O-N 3.23Å; E679-N681 VanDerWaalsContact C-N 3.29Å; E679-N681 PolarHBondContact O-N 3.29Å; E679-Y682 WeakPolarHBondContact O-CB 3.4Å; E679-Y682 PolarHBondContact O-N 3.27Å; E679-Y682 VanDerWaalsContact O-N 3.09Å; E679-I683 PolarHBondContact O-N 2.72Å; E679-I683 VanDerWaalsContact O-N 3.09Å
680L87.9Confident86.5Confident2 Ų220 Ų201%0.0110%0.095CC..Hα-helixtrans-61.2-34.1-173.1-65.5-179000113.2I473 L513 V520 F671 F678 Y682 I683 I684I473-L680 HydrophobicContact CD1-CD2 4.06Å; L513-L680 HydrophobicContact CD1-CD2 4.43Å; L513-L680 HydrophobicContact CD2-CD1 3.89Å; L513-L680 HydrophobicContact CD2-CD2 4.03Å; V520-L680 HydrophobicContact CG2-CB 3.6Å; V520-L680 HydrophobicContact CG2-CD1 3.98Å; V520-L680 HydrophobicContact CG2-CG 4.49Å; F671-L680 HydrophobicContact CD1-CD1 3.56Å; F671-L680 HydrophobicContact CD1-CG 4.39Å; F671-L680 HydrophobicContact CE1-CD1 4.14Å; F671-L680 HydrophobicContact CG-CD1 4.45Å; F678-L680 HydrophobicContact CB-CD2 4.1Å; F678-L680 HydrophobicContact CB-CG 4.22Å; F678-L680 PolarHBondContact O-N 2.86Å; L680-Y682 VanDerWaalsContact C-N 3.3Å; L680-Y682 PolarHBondContact O-N 2.81Å; L680-I683 HydrophobicContact CD2-CD1 4.31Å; L680-I683 PolarHBondContact O-N 3.16Å; L680-I684 WeakPolarHBondContact O-CB 3.2Å; L680-I684 WeakPolarHBondContact O-CD1 3.42Å; L680-I684 VanDerWaalsContact O-CG1 3.22Å; L680-I684 WeakPolarHBondContact O-CG1 3.4Å; L680-I684 PolarHBondContact O-N 3.07Å
681N85.2Confident86.7Confident6 Ų619.9 Ų19.93%0.03210%0.095CC..Hα-helixtrans-61.2-39.8176.2-79.3-56.1000112A519 R523 E679 D685A519-N681 PolarHBondContact O-ND2 2.91Å; R523-N681 WeakPolarHBondContact CD-OD1 3.25Å; R523-N681 PolarHBondContact NH1-O 2.98Å; E679-N681 VanDerWaalsContact C-N 3.29Å; E679-N681 PolarHBondContact O-N 3.29Å; N681-D685 PolarHBondContact O-N 3.38Å
682Y83.7Confident86.9Confident44 Ų4420 Ų2017%0.17310%0.095CC..Hα-helixtrans-67.3-45.4172.8163.2-109.3000111.3P358 F359 E679 L680 I684 D685 R686P358-Y682 VanDerWaalsContact CA-CE2 3.46Å; P358-Y682 HydrophobicContact CB-CE2 4.2Å; F359-Y682 HydrophobicContact CB-CD1 4.44Å; F359-Y682 HydrophobicContact CB-CE1 3.57Å; F359-Y682 WeakPolarHBondContact CB-OH 3.44Å; F359-Y682 VanDerWaalsContact N-CZ 3.32Å; F359-Y682 PolarHBondContact N-OH 3.11Å; E679-Y682 WeakPolarHBondContact O-CB 3.4Å; E679-Y682 PolarHBondContact O-N 3.27Å; E679-Y682 VanDerWaalsContact O-N 3.09Å; L680-Y682 VanDerWaalsContact C-N 3.3Å; L680-Y682 PolarHBondContact O-N 2.81Å; Y682-I684 VanDerWaalsContact C-N 3.3Å; Y682-I684 PolarHBondContact O-N 2.87Å; Y682-D685 PolarHBondContact O-N 2.91Å; Y682-R686 HydrophobicContact CD2-CB 4.3Å; Y682-R686 HydrophobicContact CE1-CB 4.47Å; Y682-R686 HydrophobicContact CE2-CB 3.76Å; Y682-R686 HydrophobicContact CE2-CG 4.2Å; Y682-R686 VanDerWaalsContact O-CB 3.23Å; Y682-R686 WeakPolarHBondContact O-CB 3.48Å; Y682-R686 PolarHBondContact O-N 3.35Å
683I88.8Confident87.1Confident12 Ų1222 Ų226%0.06211%0.105CC..Hα-helixtrans-58.6-44-180-65.7176.3000110.5I473 W475 E679 L680 N687I473-I683 HydrophobicContact CG2-CD1 4.28Å; I473-I683 HydrophobicContact CG2-CG2 4.32Å; W475-I683 HydrophobicContact CH2-CD1 3.97Å; W475-I683 HydrophobicContact CH2-CG1 3.84Å; W475-I683 HydrophobicContact CH2-CG2 4.24Å; W475-I683 HydrophobicContact CZ2-CD1 4.01Å; W475-I683 HydrophobicContact CZ2-CG1 4.38Å; W475-I683 HydrophobicContact CZ3-CG1 4.45Å; W475-I683 HydrophobicContact CZ3-CG2 4.23Å; E679-I683 PolarHBondContact O-N 2.72Å; E679-I683 VanDerWaalsContact O-N 3.09Å; L680-I683 HydrophobicContact CD2-CD1 4.31Å; L680-I683 PolarHBondContact O-N 3.16Å; I683-N687 WeakPolarHBondContact CG2-ND2 3.15Å; I683-N687 WeakPolarHBondContact O-CB 3.4Å; I683-N687 PolarHBondContact O-N 3.27Å; I683-N687 PolarHBondContact O-ND2 3.37Å; I683-N687 PolarHBondContact O-OD1 3.42Å
684I90.1Very high87.7Confident8 Ų821.2 Ų21.24%0.04110%0.103CC..Hα-helixtrans-58.2-49176-70.9159.8000111.1L510 L513 V520 F524 F535 L680 Y682 N687 L688L510-I684 HydrophobicContact CD1-CD1 3.69Å; L510-I684 HydrophobicContact CD1-CG1 4.33Å; L510-I684 HydrophobicContact CD1-CG2 4.5Å; L513-I684 HydrophobicContact CD1-CD1 4.06Å; L513-I684 HydrophobicContact CD1-CG1 3.9Å; V520-I684 HydrophobicContact CB-CD1 4.46Å; V520-I684 HydrophobicContact CG1-CD1 3.69Å; V520-I684 HydrophobicContact CG2-CD1 3.84Å; F524-I684 HydrophobicContact CE2-CD1 4.31Å; F524-I684 HydrophobicContact CE2-CG2 4.42Å; F524-I684 HydrophobicContact CZ-CG2 4.4Å; F535-I684 HydrophobicContact CE1-CG2 4.27Å; F535-I684 HydrophobicContact CE2-CG2 4.23Å; F535-I684 HydrophobicContact CZ-CG2 3.5Å; F535-I684 VanDerWaalsContact CZ-CG2 3.5Å; L680-I684 WeakPolarHBondContact O-CB 3.2Å; L680-I684 WeakPolarHBondContact O-CD1 3.42Å; L680-I684 VanDerWaalsContact O-CG1 3.22Å; L680-I684 WeakPolarHBondContact O-CG1 3.4Å; L680-I684 PolarHBondContact O-N 3.07Å; Y682-I684 VanDerWaalsContact C-N 3.3Å; Y682-I684 PolarHBondContact O-N 2.87Å; I684-N687 PolarHBondContact O-N 3.36Å; I684-L688 PolarHBondContact O-N 3.33Å; I684-L688 VanDerWaalsContact O-N 3.13Å
685D86.6Confident88.1Confident17 Ų1720.2 Ų20.29%0.09110%0.098CC..Hα-helixtrans-63.2-50.3-179.5-74.2-3.1000111.9I345 R523 N681 Y682 N687 L688 Q689I345-D685 WeakPolarHBondContact CD1-OD1 3.37Å; R523-D685 IonicContact CZ-OD1 2.68Å; R523-D685 IonicContact CZ-OD2 3.01Å; R523-D685 IonicContact NH1-OD1 3.83Å; R523-D685 PolarHBondContact NH1-OD1 3.3Å; R523-D685 IonicContact NH1-OD2 3.59Å; R523-D685 IonicContact NH2-OD1 2.97Å; R523-D685 PolarHBondContact NH2-OD1 3.33Å; R523-D685 IonicContact NH2-OD2 3.93Å; R523-D685 PolarHBondContact NH2-OD2 3.41Å; N681-D685 PolarHBondContact O-N 3.38Å; Y682-D685 PolarHBondContact O-N 2.91Å; D685-N687 VanDerWaalsContact C-N 3.3Å; D685-N687 PolarHBondContact O-N 2.92Å; D685-L688 PolarHBondContact O-N 3.17Å; D685-Q689 WeakPolarHBondContact O-CB 3.49Å; D685-Q689 VanDerWaalsContact O-CG 3.23Å; D685-Q689 WeakPolarHBondContact O-CG 3.44Å; D685-Q689 PolarHBondContact O-N 2.98Å
686R88.4Confident88.4Confident53 Ų5321.2 Ų21.220%0.210%0.103CC..Hα-helixtrans-59.8-44.6-179.6178.2-86.5-176.5-169.1-3.1110.6D477 Y682 L690D477-R686 IonicContact OD1-CZ 2.72Å; D477-R686 IonicContact OD1-NH1 2.83Å; D477-R686 PolarHBondContact OD1-NH1 3.12Å; D477-R686 IonicContact OD1-NH2 3.69Å; D477-R686 PolarHBondContact OD1-NH2 3.45Å; D477-R686 IonicContact OD2-CZ 3.27Å; D477-R686 IonicContact OD2-NH1 2.66Å; D477-R686 PolarHBondContact OD2-NH1 3.36Å; D477-R686 IonicContact OD2-NH2 3.63Å; Y682-R686 HydrophobicContact CD2-CB 4.3Å; Y682-R686 HydrophobicContact CE1-CB 4.47Å; Y682-R686 HydrophobicContact CE2-CB 3.76Å; Y682-R686 HydrophobicContact CE2-CG 4.2Å; Y682-R686 VanDerWaalsContact O-CB 3.23Å; Y682-R686 WeakPolarHBondContact O-CB 3.48Å; Y682-R686 PolarHBondContact O-N 3.35Å; R686-L690 WeakPolarHBondContact O-CB 3.36Å; R686-L690 PolarHBondContact O-N 3.44Å
687N93.1Very high88.4Confident4 Ų421.4 Ų21.42%0.02110%0.103CC..Hα-helixtrans-65.1-45.3-177-77-4.9000111.2S474 P476 N506 I683 I684 D685 C691S474-N687 PolarHBondContact O-ND2 3.43Å; P476-N687 WeakPolarHBondContact CD-ND2 3.28Å; P476-N687 HydrophobicContact CG-CB 3.7Å; N506-N687 WeakPolarHBondContact OD1-CB 3.29Å; I683-N687 WeakPolarHBondContact CG2-ND2 3.15Å; I683-N687 WeakPolarHBondContact O-CB 3.4Å; I683-N687 PolarHBondContact O-N 3.27Å; I683-N687 PolarHBondContact O-ND2 3.37Å; I683-N687 PolarHBondContact O-OD1 3.42Å; I684-N687 PolarHBondContact O-N 3.36Å; D685-N687 VanDerWaalsContact C-N 3.3Å; D685-N687 PolarHBondContact O-N 2.92Å; N687-C691 WeakPolarHBondContact O-CB 3.48Å; N687-C691 PolarHBondContact O-N 2.88Å; N687-C691 PolarHBondContact O-SG 3Å
688L91.8Very high88.3Confident0 Ų028.3 Ų28.30%013%0.13CC..Hα-helixtrans-66.5-45.5177.5-169.367.9000111.9I345 N506 F535 I684 D685 C691 Y692I345-L688 HydrophobicContact CD1-CB 4.18Å; I345-L688 HydrophobicContact CD1-CD2 3.7Å; I345-L688 HydrophobicContact CG1-CD2 4.01Å; N506-L688 HydrophobicContact CB-CD1 4.25Å; F535-L688 HydrophobicContact CD1-CD2 4.45Å; F535-L688 HydrophobicContact CE1-CB 4.32Å; F535-L688 HydrophobicContact CE1-CD1 4.21Å; F535-L688 HydrophobicContact CE1-CD2 3.92Å; F535-L688 HydrophobicContact CE1-CG 4.38Å; F535-L688 HydrophobicContact CE2-CD2 4.39Å; F535-L688 HydrophobicContact CZ-CB 4.43Å; F535-L688 HydrophobicContact CZ-CD2 3.88Å; I684-L688 PolarHBondContact O-N 3.33Å; I684-L688 VanDerWaalsContact O-N 3.13Å; D685-L688 PolarHBondContact O-N 3.17Å; L688-C691 PolarHBondContact O-N 2.84Å; L688-Y692 HydrophobicContact CD1-CD2 4.39Å; L688-Y692 HydrophobicContact CD1-CE1 4.38Å; L688-Y692 HydrophobicContact CD1-CE2 3.81Å; L688-Y692 HydrophobicContact CD2-CE2 4.06Å; L688-Y692 HydrophobicContact CG-CD2 4.11Å; L688-Y692 HydrophobicContact CG-CE2 3.75Å; L688-Y692 PolarHBondContact O-N 3.09Å
689Q88.1Confident88.2Confident43 Ų4329.2 Ų29.220%0.20113%0.134CC..Hα-helixtrans-59.5-51178.4-75.4169.19.300111.7T343 D685 C691 Y692 L693T343-Q689 VanDerWaalsContact O-CG 3.26Å; T343-Q689 WeakPolarHBondContact O-CG 3.47Å; T343-Q689 PolarHBondContact O-NE2 3.41Å; T343-Q689 WeakPolarHBondContact OG1-CG 3.36Å; D685-Q689 WeakPolarHBondContact O-CB 3.49Å; D685-Q689 VanDerWaalsContact O-CG 3.23Å; D685-Q689 WeakPolarHBondContact O-CG 3.44Å; D685-Q689 PolarHBondContact O-N 2.98Å; Q689-C691 VanDerWaalsContact C-N 3.35Å; Q689-C691 PolarHBondContact O-N 3.23Å; Q689-Y692 PolarHBondContact O-N 3.05Å; Q689-L693 WeakPolarHBondContact O-CG 3.37Å; Q689-L693 PolarHBondContact O-N 2.99Å
690L88.7Confident88.1Confident44 Ų4431.5 Ų31.523%0.2316%0.164CC..Hα-helixtrans-63.4-42.9179.9179.7141.2000111.3D477 R686 Y692 L693 V694D477-L690 HydrophobicContact CB-CD2 4.16Å; D477-L690 WeakPolarHBondContact OD1-CD1 3.44Å; D477-L690 WeakPolarHBondContact OD1-CD2 3.39Å; R686-L690 WeakPolarHBondContact O-CB 3.36Å; R686-L690 PolarHBondContact O-N 3.44Å; L690-Y692 VanDerWaalsContact C-N 3.33Å; L690-Y692 PolarHBondContact O-N 3.47Å; L690-L693 PolarHBondContact O-N 2.89Å; L690-V694 HydrophobicContact CD2-CG2 4.04Å; L690-V694 HydrophobicContact CG-CG2 4.19Å; L690-V694 WeakPolarHBondContact O-CB 3.5Å; L690-V694 VanDerWaalsContact O-CG2 3.27Å; L690-V694 WeakPolarHBondContact O-CG2 3.47Å; L690-V694 PolarHBondContact O-N 3.38Å
691C94.3Very high87.6Confident0 Ų038.5 Ų38.50%019%0.19CC..Hα-helixtrans-54.8-50.9176.2-80.20000111.2P476 A480 V502 N506 N687 L688 Q689 V694 V695P476-C691 VanDerWaalsContact CG-SG 3.51Å; A480-C691 HydrophobicContact CB-CB 4.31Å; V502-C691 HydrophobicContact CB-CB 3.71Å; V502-C691 HydrophobicContact CG1-CB 4.19Å; V502-C691 HydrophobicContact CG2-CB 3.81Å; N506-C691 PolarHBondContact ND2-SG 2.95Å; N506-C691 VanDerWaalsContact ND2-SG 3.41Å; N687-C691 WeakPolarHBondContact O-CB 3.48Å; N687-C691 PolarHBondContact O-N 2.88Å; N687-C691 PolarHBondContact O-SG 3Å; L688-C691 PolarHBondContact O-N 2.84Å; Q689-C691 VanDerWaalsContact C-N 3.35Å; Q689-C691 PolarHBondContact O-N 3.23Å; C691-V694 PolarHBondContact O-N 3.26Å; C691-V695 VanDerWaalsContact O-CG2 3.31Å; C691-V695 WeakPolarHBondContact O-CG2 3.46Å; C691-V695 PolarHBondContact O-N 3.4Å
692Y92.5Very high87.1Confident5 Ų544 Ų442%0.0222%0.224CC..Hα-helixtrans-65-41.6179-70.4-28.4000113.1H337 T343 R499 V502 R503 L688 Q689 L690 V694 V695 D696H337-Y692 HydrophobicContact CB-CE2 4.16Å; T343-Y692 HydrophobicContact CG2-CD2 3.49Å; T343-Y692 VanDerWaalsContact CG2-CD2 3.49Å; T343-Y692 HydrophobicContact CG2-CE2 3.92Å; R499-Y692 HydrophobicContact CB-CD1 4.47Å; R499-Y692 HydrophobicContact CB-CE1 4.15Å; R499-Y692 HydrophobicContact CG-CD1 4.24Å; R499-Y692 HydrophobicContact CG-CE1 4.38Å; V502-Y692 HydrophobicContact CG2-CD1 4.04Å; V502-Y692 HydrophobicContact CG2-CE1 4.09Å; R503-Y692 WeakPolarHBondContact CD-OH 3.15Å; L688-Y692 HydrophobicContact CD1-CD2 4.39Å; L688-Y692 HydrophobicContact CD1-CE1 4.38Å; L688-Y692 HydrophobicContact CD1-CE2 3.81Å; L688-Y692 HydrophobicContact CD2-CE2 4.06Å; L688-Y692 HydrophobicContact CG-CD2 4.11Å; L688-Y692 HydrophobicContact CG-CE2 3.75Å; L688-Y692 PolarHBondContact O-N 3.09Å; Q689-Y692 PolarHBondContact O-N 3.05Å; L690-Y692 VanDerWaalsContact C-N 3.33Å; L690-Y692 PolarHBondContact O-N 3.47Å; Y692-V694 VanDerWaalsContact C-N 3.3Å; Y692-V694 PolarHBondContact O-N 2.86Å; Y692-V695 HydrophobicContact CD1-CG2 4.48Å; Y692-V695 PolarHBondContact O-N 3.39Å; Y692-D696 WeakPolarHBondContact O-CB 3.4Å; Y692-D696 PolarHBondContact O-N 3.43Å
693L88.6Confident86.6Confident45 Ų4547.5 Ų47.524%0.23625%0.252CS..Iπ-helixtrans-57-44.8173.8-73.4171.2000111.7E341 Q689 L690 E697 Y698E341-L693 WeakPolarHBondContact O-CD2 3.48Å; Q689-L693 WeakPolarHBondContact O-CG 3.37Å; Q689-L693 PolarHBondContact O-N 2.99Å; L690-L693 PolarHBondContact O-N 2.89Å; L693-E697 HydrophobicContact CD2-CB 4.14Å; L693-E697 HydrophobicContact CD2-CG 4.39Å; L693-E697 PolarHBondContact O-N 3.33Å; L693-Y698 HydrophobicContact CB-CD2 4.07Å; L693-Y698 HydrophobicContact CB-CE2 4.16Å; L693-Y698 HydrophobicContact CD2-CE2 4.33Å; L693-Y698 WeakPolarHBondContact O-CD2 3.37Å; L693-Y698 PolarHBondContact O-N 3.03Å
694V90.4Very high85.6Confident31 Ų3151.8 Ų51.819%0.18829%0.289CS..Iπ-helixtrans-70.3-41.8-177.6171.40000112.6A480 S484 L690 C691 Y692A480-V694 HydrophobicContact CB-CB 4.17Å; A480-V694 HydrophobicContact CB-CG1 4.02Å; S484-V694 WeakPolarHBondContact CB-O 3.23Å; S484-V694 PolarHBondContact OG-O 2.85Å; L690-V694 HydrophobicContact CD2-CG2 4.04Å; L690-V694 HydrophobicContact CG-CG2 4.19Å; L690-V694 WeakPolarHBondContact O-CB 3.5Å; L690-V694 VanDerWaalsContact O-CG2 3.27Å; L690-V694 WeakPolarHBondContact O-CG2 3.47Å; L690-V694 PolarHBondContact O-N 3.38Å; C691-V694 PolarHBondContact O-N 3.26Å; Y692-V694 VanDerWaalsContact C-N 3.3Å; Y692-V694 PolarHBondContact O-N 2.86Å
695V91.8Very high84.1Confident0 Ų058 Ų580%033%0.327CS..Iπ-helixtrans-86.3-9.5-175.7-58.80000114.8A480 V483 R498 R499 V502 C691 Y692 H699A480-V695 HydrophobicContact CB-CG1 4.28Å; V483-V695 HydrophobicContact CB-CG1 4.5Å; V483-V695 HydrophobicContact CG1-CG1 4.11Å; R498-V695 HydrophobicContact CB-CB 3.9Å; R498-V695 HydrophobicContact CB-CG1 4.41Å; R498-V695 HydrophobicContact CB-CG2 4.29Å; R498-V695 PolarHBondContact NE-O 3.2Å; R499-V695 HydrophobicContact CG-CG2 3.99Å; V502-V695 HydrophobicContact CG1-CG1 3.66Å; V502-V695 HydrophobicContact CG2-CG1 4.39Å; V502-V695 HydrophobicContact CG2-CG2 3.95Å; C691-V695 VanDerWaalsContact O-CG2 3.31Å; C691-V695 WeakPolarHBondContact O-CG2 3.46Å; C691-V695 PolarHBondContact O-N 3.4Å; Y692-V695 HydrophobicContact CD1-CG2 4.48Å; Y692-V695 PolarHBondContact O-N 3.39Å; V695-H699 WeakPolarHBondContact O-CB 3.49Å
696D87.1Confident82.5Confident37 Ų3760 Ų6020%0.19835%0.352CS..Iπ-helixtrans-125.6-77-172.5-157.10.7000110.9R495 R499 Y692 Y698 H699R495-D696 WeakPolarHBondContact CD-OD1 3.47Å; R495-D696 IonicContact CZ-OD1 3.97Å; R495-D696 IonicContact CZ-OD2 2.71Å; R495-D696 VanDerWaalsContact CZ-OD2 3.23Å; R495-D696 IonicContact NE-OD1 2.68Å; R495-D696 PolarHBondContact NE-OD1 3.22Å; R495-D696 IonicContact NE-OD2 3.53Å; R495-D696 PolarHBondContact NE-OD2 3.49Å; R495-D696 IonicContact NH2-OD1 3.49Å; R495-D696 IonicContact NH2-OD2 2.91Å; R495-D696 PolarHBondContact NH2-OD2 3.02Å; R499-D696 IonicContact CZ-OD2 3.7Å; R499-D696 IonicContact NH1-OD2 3.51Å; R499-D696 PolarHBondContact NH1-OD2 3.25Å; Y692-D696 WeakPolarHBondContact O-CB 3.4Å; Y692-D696 PolarHBondContact O-N 3.43Å; D696-Y698 PolarHBondContact O-N 3.45Å; D696-H699 WeakPolarHBondContact O-CB 3.49Å; D696-H699 PolarHBondContact O-N 3.07Å
697E82.7Confident80.7Confident59 Ų5964.2 Ų64.228%0.27638%0.383SS..Iπ-helixtrans-64.7-38.8-172.4-179.757.6-167.300112.8L693 R701L693-E697 HydrophobicContact CD2-CB 4.14Å; L693-E697 HydrophobicContact CD2-CG 4.39Å; L693-E697 PolarHBondContact O-N 3.33Å; E697-R701 VanDerWaalsContact CD-NH1 3.27Å; E697-R701 WeakPolarHBondContact O-CD 3.44Å; E697-R701 PolarHBondContact O-NE 2.94Å; E697-R701 PolarHBondContact O-NH1 3.13Å; E697-R701 PolarHBondContact O-NH2 2.7Å; E697-R701 IonicContact OE1-CZ 3.62Å; E697-R701 IonicContact OE1-NH1 2.74Å; E697-R701 PolarHBondContact OE1-NH1 2.89Å; E697-R701 IonicContact OE1-NH2 2.78Å; E697-R701 IonicContact OE2-CZ 2.75Å; E697-R701 IonicContact OE2-NH1 3.73Å; E697-R701 IonicContact OE2-NH2 2.58Å; E697-R701 PolarHBondContact OE2-NH2 3.21Å
698Y84.9Confident78.2Confident145 Ų14570.2 Ų70.257%0.56942%0.42SS*.THydrogen-bonded Turntrans-99.84.3179-64-67.1000113.7L693 D696 G700 R701L693-Y698 HydrophobicContact CB-CD2 4.07Å; L693-Y698 HydrophobicContact CB-CE2 4.16Å; L693-Y698 HydrophobicContact CD2-CE2 4.33Å; L693-Y698 WeakPolarHBondContact O-CD2 3.37Å; L693-Y698 PolarHBondContact O-N 3.03Å; D696-Y698 PolarHBondContact O-N 3.45Å; Y698-G700 PolarHBondContact O-N 3.46Å; Y698-R701 PolarHBondContact O-N 2.89Å
699H86.6Confident75.8Confident36 Ų3675.2 Ų75.217%0.16746%0.462CS..THydrogen-bonded Turntrans-63.6120.5178.3175.870.2000110.8S484 R498 V695 D696 R701S484-H699 PolarHBondContact O-CE1 2.78Å; S484-H699 PolarHBondContact O-ND1 3.14Å; S484-H699 PolarHBondContact OG-ND1 3.2Å; S484-H699 VanDerWaalsContact OG-ND1 3.14Å; R498-H699 VanDerWaalsContact CZ-CD2 3.47Å; R498-H699 PolarHBondContact NH1-NE2 3.37Å; R498-H699 PolarHBondContact NH2-CD2 3.46Å; R498-H699 PolarHBondContact NH2-NE2 3.48Å; V695-H699 WeakPolarHBondContact O-CB 3.49Å; D696-H699 WeakPolarHBondContact O-CB 3.49Å; D696-H699 PolarHBondContact O-N 3.07Å; H699-R701 PolarHBondContact O-N 2.95Å; H699-R701 VanDerWaalsContact O-N 3.09Å
700G79.1Confident73.5Confident71 Ų7176.3 Ų76.373%0.73249%0.485SS*.THydrogen-bonded Turntrans67.52.6179.600000115.1Y698Y698-G700 PolarHBondContact O-N 3.46Å
701R78.1Confident71.1Confident148 Ų14882 Ų8256%0.55851%0.51SS*.  trans-89.2120.4178.8-61.9-161.9-169.416117110.1E697 Y698 H699E697-R701 VanDerWaalsContact CD-NH1 3.27Å; E697-R701 WeakPolarHBondContact O-CD 3.44Å; E697-R701 PolarHBondContact O-NE 2.94Å; E697-R701 PolarHBondContact O-NH1 3.13Å; E697-R701 PolarHBondContact O-NH2 2.7Å; E697-R701 IonicContact OE1-CZ 3.62Å; E697-R701 IonicContact OE1-NH1 2.74Å; E697-R701 PolarHBondContact OE1-NH1 2.89Å; E697-R701 IonicContact OE1-NH2 2.78Å; E697-R701 IonicContact OE2-CZ 2.75Å; E697-R701 IonicContact OE2-NH1 3.73Å; E697-R701 IonicContact OE2-NH2 2.58Å; E697-R701 PolarHBondContact OE2-NH2 3.21Å; Y698-R701 PolarHBondContact O-N 2.89Å; H699-R701 PolarHBondContact O-N 2.95Å; H699-R701 VanDerWaalsContact O-N 3.09Å
702V74.3Confident68.5Low123 Ų12388.3 Ų88.375%0.74555%0.551SS**  trans-114145.9166.6-68.70000108.7
703P71.9Confident66.1Low116 Ų11696 Ų9675%0.75359%0.587SS**  trans-54147169.9-23.433.8000110.5V705P703-V705 PolarHBondContact O-N 2.71Å; P703-V705 VanDerWaalsContact O-N 3.07Å
704A69.2Low63.7Low102 Ų10296.8 Ų96.884%0.84361%0.605SS**  trans-54.3119.9175.300000109.3G706A704-G706 PolarHBondContact O-N 3.23Å
705V58Low61Low138 Ų138105.1 Ų105.184%0.83664%0.642SS**  trans-76.678.3173.9-174.50000106.5P703 V707P703-V705 PolarHBondContact O-N 2.71Å; P703-V705 VanDerWaalsContact O-N 3.07Å; V705-V707 PolarHBondContact O-N 3.36Å
706G52.6Low58.3Low61 Ų61111.2 Ų111.263%0.62968%0.68SS**PPolyproline II helixtrans-67.7122.4177.500000109.8A704 T708A704-G706 PolarHBondContact O-N 3.23Å; G706-T708 PolarHBondContact O-N 3.27Å
707V50.7Low55.8Low140 Ų140114.3 Ų114.385%0.84871%0.71SS**PPolyproline II helixtrans-59.3126157.5-174.50000105.9V705 A709V705-V707 PolarHBondContact O-N 3.36Å; V707-A709 PolarHBondContact O-N 3.17Å; V707-A709 VanDerWaalsContact O-N 3.14Å
708T41.7Very low53.6Low130 Ų130117.7 Ų117.780%0.79874%0.735SS**SBendtrans-51.3119.7-177.844.70000111.5G706G706-T708 PolarHBondContact O-N 3.27Å
709A39.7Very low51.2Low105 Ų105114.8 Ų114.887%0.86874%0.741SS**SBendtrans51.586.6155.200000117.3V707V707-A709 PolarHBondContact O-N 3.17Å; V707-A709 VanDerWaalsContact O-N 3.14Å
710G39.8Very low48.7Very low67 Ų67122.4 Ų122.469%0.69178%0.776SS**  trans-163.3120.3155.900000108.8
711E38.9Very low46.6Very low163 Ų163129 Ų12976%0.76278%0.779SS**  trans89.6112.8167-55-178.817700118H713E711-H713 PolarHBondContact O-N 2.91Å
712P39.8Very low44.4Very low132 Ų132132 Ų13286%0.85780%0.796SS**  trans-82.696.5175.732.5-28.9000109.6G714P712-G714 PolarHBondContact O-N 3.45Å
713H41.3Very low42.6Very low168 Ų168132.7 Ų132.778%0.77880%0.8SS**  trans-84.3111.1170.8-80.5-57.6000111.7E711E711-H713 PolarHBondContact O-N 2.91Å
714G38.5Very low40.9Very low60 Ų60132.3 Ų132.362%0.61980%0.8SS**  trans28.2113.514000000118.4P712 T716P712-G714 PolarHBondContact O-N 3.45Å; G714-T716 PolarHBondContact O-N 3.02Å
715E33.4Very low39.3Very low206 Ų206135.4 Ų135.496%0.96380%0.797SS**  trans-38.496.9165.7-61.8173.3161.600112.9A717E715-A717 PolarHBondContact O-N 3.45Å
716T36.4Very low38.1Very low128 Ų128139.2 Ų139.279%0.78580%0.802SS**  trans-84.9110.1163.116.90000107.7G714 V718G714-T716 PolarHBondContact O-N 3.02Å; T716-V718 PolarHBondContact O-N 2.68Å
717A33.4Very low37.7Very low102 Ų102143.5 Ų143.584%0.84380%0.8SS**  trans-5794.7176.900000110.8E715 A719E715-A717 PolarHBondContact O-N 3.45Å; A717-A719 PolarHBondContact O-N 2.79Å; A717-A719 VanDerWaalsContact O-N 3.14Å
718V36.4Very low37Very low131 Ų131143 Ų14379%0.79480%0.797SS**  trans-69.1111.4170.4178.70000107.5T716 Q720T716-V718 PolarHBondContact O-N 2.68Å; V718-Q720 PolarHBondContact O-N 3.1Å; V718-Q720 VanDerWaalsContact O-N 3.1Å
719A35.6Very low37.1Very low83 Ų83141.2 Ų141.269%0.68679%0.788SS**  trans-47.2117175.600000110.6A717 R721A717-A719 PolarHBondContact O-N 2.79Å; A717-A719 VanDerWaalsContact O-N 3.14Å; A719-R721 VanDerWaalsContact C-N 3.27Å; A719-R721 PolarHBondContact O-N 3.28Å
720Q33Very low37.2Very low196 Ų196142.4 Ų142.492%0.91677%0.774SS**  trans-65.382177.7-68.6177.7-14.100110.2V718 K722V718-Q720 PolarHBondContact O-N 3.1Å; V718-Q720 VanDerWaalsContact O-N 3.1Å; Q720-K722 PolarHBondContact O-N 2.89Å
721R35.1Very low37.3Very low210 Ų210143.9 Ų143.979%0.79276%0.761SS**  trans-69.9124165.3-86.7-176.8174.2175.50108.4A719 V723A719-R721 VanDerWaalsContact C-N 3.27Å; A719-R721 PolarHBondContact O-N 3.28Å; R721-V723 PolarHBondContact O-N 3.42Å
722K33.3Very low37.3Very low211 Ų211139.3 Ų139.392%0.91775%0.745SS**  trans-51.4101.2177.1-75.9176.3174.7175.10110.2Q720 S724Q720-K722 PolarHBondContact O-N 2.89Å; K722-S724 PolarHBondContact O-N 3.49Å; K722-S724 VanDerWaalsContact O-N 3.09Å
723V36.4Very low37.6Very low137 Ų137134.6 Ų134.683%0.8372%0.716SS**  trans-67.4105.2175.4178.50000108.6R721 H725R721-V723 PolarHBondContact O-N 3.42Å; V723-H725 PolarHBondContact O-N 3.15Å; V723-H725 VanDerWaalsContact O-N 3.16Å
724S36.4Very low37.5Very low108 Ų108130.8 Ų130.876%0.75571%0.705SS**  trans-68.7110.9171.766.30000109.6K722K722-S724 PolarHBondContact O-N 3.49Å; K722-S724 VanDerWaalsContact O-N 3.09Å
725H34.4Very low37.8Very low168 Ų168131 Ų13178%0.77870%0.7SS**  trans56.6106.8159.1-77.628.3000117.5V723 R727V723-H725 PolarHBondContact O-N 3.15Å; V723-H725 VanDerWaalsContact O-N 3.16Å; H725-R727 PolarHBondContact O-N 2.98Å
726K33Very low38.3Very low217 Ų217127.5 Ų127.594%0.94368%0.684SS**  trans-30.794.6159.3-69173.8174.8176.80112.7
727R44.2Very low38.8Very low151 Ų151125.9 Ų125.957%0.5767%0.67SS**  trans-103.7111.9158.5-72.5-174.7-178.8177.45.5106.4T344 H725 P729T344-R727 PolarHBondContact OG1-NH1 2.82Å; T344-R727 VanDerWaalsContact OG1-NH1 3.1Å; T344-R727 PolarHBondContact OG1-NH2 3.33Å; H725-R727 PolarHBondContact O-N 2.98Å; R727-P729 VanDerWaalsContact O-CD 3.29Å; R727-P729 WeakPolarHBondContact O-CD 3.21Å
728T37.3Very low39.5Very low129 Ų129131.8 Ų131.879%0.79167%0.67SS**  trans-63.2118.5174.141.60000108.2
729P42.3Very low39.9Very low94 Ų94129.4 Ų129.461%0.6165%0.652SS**  trans-67.1166-177.526.1-33.2000111.8R727 K731R727-P729 VanDerWaalsContact O-CD 3.29Å; R727-P729 WeakPolarHBondContact O-CD 3.21Å; P729-K731 PolarHBondContact O-N 3.28Å; P729-K731 VanDerWaalsContact O-N 3.07Å
730F43.1Very low40.6Very low130 Ų130128.4 Ų128.457%0.5764%0.639SS**  trans-51.4114.7164.4169.7-101.6000109.2P732F730-P732 HydrophobicContact CE1-CB 4.3Å; F730-P732 HydrophobicContact CE1-CG 4.33Å; F730-P732 HydrophobicContact CZ-CB 4.14Å
731K40.6Very low41.4Very low97 Ų97126.2 Ų126.242%0.42263%0.633SS.*  trans-112.1119.3165.1-74.7-172-177.4-1760106.7P729 A735 E736P729-K731 PolarHBondContact O-N 3.28Å; P729-K731 VanDerWaalsContact O-N 3.07Å; K731-A735 HydrophobicContact CB-CB 4.2Å; K731-E736 HydrophobicContact CD-CG 3.97Å; K731-E736 WeakPolarHBondContact CD-OE1 3.22Å; K731-E736 WeakPolarHBondContact CE-OE1 3.46Å; K731-E736 IonicContact NZ-OE1 3.75Å; K731-E736 PolarHBondContact NZ-OE1 3Å
732P39.7Very low41.9Very low67 Ų67126.4 Ų126.444%0.43563%0.633SS.*  trans-57.2155.7173.119.9-26000109.7F730 T734 A735F730-P732 HydrophobicContact CE1-CB 4.3Å; F730-P732 HydrophobicContact CE1-CG 4.33Å; F730-P732 HydrophobicContact CZ-CB 4.14Å; P732-T734 PolarHBondContact O-N 3.04Å; P732-A735 HydrophobicContact CG-CB 4.17Å; P732-A735 WeakPolarHBondContact O-CB 3.49Å; P732-A735 PolarHBondContact O-N 3Å
733S45.3Very low42.6Very low34 Ų34122.1 Ų122.124%0.23862%0.62CS.*THydrogen-bonded Turntrans-62.7-25.1-15677.70000114.4P361 T363P361-S733 VanDerWaalsContact CG-CB 3.49Å; T363-S733 CarbonylContact C-O 3.56Å; T363-S733 VanDerWaalsContact C-O 3.26Å; T363-S733 VanDerWaalsContact OG1-CA 3.32Å; T363-S733 WeakPolarHBondContact OG1-CA 3.5Å; T363-S733 WeakPolarHBondContact OG1-CB 3.33Å; T363-S733 PolarHBondContact OG1-O 3.34Å; T363-S733 PolarHBondContact OG1-OG 2.89Å
734T40.7Very low43Very low88 Ų88121 Ų12154%0.5461%0.605SS.*THydrogen-bonded Turntrans-101.6-0.3179.253.20000113.3P732 E736 L737P732-T734 PolarHBondContact O-N 3.04Å; T734-E736 PolarHBondContact O-N 3.38Å; T734-E736 VanDerWaalsContact O-N 3.16Å; T734-L737 HydrophobicContact CG2-CD2 4.35Å; T734-L737 WeakPolarHBondContact O-CB 3.24Å; T734-L737 PolarHBondContact O-N 2.79Å
735A43.5Very low43.1Very low63 Ų63119.4 Ų119.452%0.52160%0.599SS.*THydrogen-bonded Turntrans-62.4-27.8-174.500000113.2K731 P732K731-A735 HydrophobicContact CB-CB 4.2Å; P732-A735 HydrophobicContact CG-CB 4.17Å; P732-A735 WeakPolarHBondContact O-CB 3.49Å; P732-A735 PolarHBondContact O-N 3Å
736E44.9Very low43.1Very low133 Ų133117 Ų11762%0.62160%0.596SS**THydrogen-bonded Turntrans-106.74.2174.6-60.7-166174.100113.4K731 T734 R738K731-E736 HydrophobicContact CD-CG 3.97Å; K731-E736 WeakPolarHBondContact CD-OE1 3.22Å; K731-E736 WeakPolarHBondContact CE-OE1 3.46Å; K731-E736 IonicContact NZ-OE1 3.75Å; K731-E736 PolarHBondContact NZ-OE1 3Å; T734-E736 PolarHBondContact O-N 3.38Å; T734-E736 VanDerWaalsContact O-N 3.16Å; E736-R738 PolarHBondContact O-N 3.41Å
737L46.9Very low43.2Very low94 Ų94113.6 Ų113.649%0.49259%0.593SS.*  trans-71.381.3176.8-168.978.7000108.9L366 T734 I739L366-L737 HydrophobicContact CD1-CD1 4.38Å; T734-L737 HydrophobicContact CG2-CD2 4.35Å; T734-L737 WeakPolarHBondContact O-CB 3.24Å; T734-L737 PolarHBondContact O-N 2.79Å; L737-I739 PolarHBondContact O-N 3.46Å
738R46.7Very low42.7Very low227 Ų227114.4 Ų114.486%0.85760%0.604SS**  trans-70.599.8165.6-73.3-173.8178.8-173.2-0.7107.4E736 P740E736-R738 PolarHBondContact O-N 3.41Å; R738-P740 VanDerWaalsContact O-CD 3.25Å; R738-P740 WeakPolarHBondContact O-CD 3.41Å; R738-P740 VanDerWaalsContact O-N 3.17Å
739I45.3Very low42.3Very low80 Ų80117.1 Ų117.141%0.4161%0.607SS.*  trans-57.2118162.9-56.2177.9000105.6L737 L741 L743 Q744L737-I739 PolarHBondContact O-N 3.46Å; I739-L741 PolarHBondContact O-N 3.21Å; I739-L743 HydrophobicContact CG2-CB 3.51Å; I739-Q744 HydrophobicContact CB-CG 3.63Å; I739-Q744 HydrophobicContact CG2-CG 3.5Å; I739-Q744 PolarHBondContact O-NE2 2.82Å
740P50.9Low41.6Very low63 Ų63117.5 Ų117.541%0.40962%0.618SS.*  trans-50136.1175.8-25.632.8000109.4R738 R742 L743 Q744R738-P740 VanDerWaalsContact O-CD 3.25Å; R738-P740 WeakPolarHBondContact O-CD 3.41Å; R738-P740 VanDerWaalsContact O-N 3.17Å; P740-R742 HydrophobicContact CB-CG 4.06Å; P740-R742 PolarHBondContact O-N 2.86Å; P740-L743 HydrophobicContact CG-CD1 4.27Å; P740-L743 WeakPolarHBondContact O-CA 3.41Å; P740-L743 WeakPolarHBondContact O-CB 3.43Å; P740-L743 PolarHBondContact O-N 3.13Å; P740-Q744 PolarHBondContact O-N 3.49Å
741L48.9Very low40.9Very low149 Ų149117.5 Ų117.578%0.7863%0.629SS**Hα-helixtrans-46.4-36.2-177.9-94.7150.7000113.2I739 L743 Q744I739-L741 PolarHBondContact O-N 3.21Å; L741-L743 PolarHBondContact O-N 3.07Å; L741-L743 VanDerWaalsContact O-N 3.13Å; L741-Q744 PolarHBondContact O-N 3.05Å
742R46.1Very low40.3Very low214 Ų214117.3 Ų117.381%0.80864%0.64SS**Hα-helixtrans-60.3-19.3175.373.6178.6-175.9176.61.7115.5P740P740-R742 HydrophobicContact CB-CG 4.06Å; P740-R742 PolarHBondContact O-N 2.86Å
743L47.8Very low39.7Very low122 Ų122122.2 Ų122.264%0.63966%0.661SS**Hα-helixtrans-106.3-4.5178.6-67.9178.7000112.4I739 P740 L741I739-L743 HydrophobicContact CG2-CB 3.51Å; P740-L743 HydrophobicContact CG-CD1 4.27Å; P740-L743 WeakPolarHBondContact O-CA 3.41Å; P740-L743 WeakPolarHBondContact O-CB 3.43Å; P740-L743 PolarHBondContact O-N 3.13Å; L741-L743 PolarHBondContact O-N 3.07Å; L741-L743 VanDerWaalsContact O-N 3.13Å
744Q45.2Very low38.9Very low112 Ų112129.4 Ų129.452%0.52369%0.691SS.*Hα-helixtrans-94-11.4176.8-64.9-175.7-1100112.8I739 P740 L741 V746I739-Q744 HydrophobicContact CB-CG 3.63Å; I739-Q744 HydrophobicContact CG2-CG 3.5Å; I739-Q744 PolarHBondContact O-NE2 2.82Å; P740-Q744 PolarHBondContact O-N 3.49Å; L741-Q744 PolarHBondContact O-N 3.05Å; Q744-V746 PolarHBondContact O-N 3.18Å
745A38.2Very low38.2Very low76 Ų76135 Ų13563%0.62871%0.708SS**  trans-75.2121.6-175.400000111
746V35.2Very low37.4Very low116 Ų116143 Ų14370%0.70373%0.725SS**  trans-56.8141.2151.8178.70000106.7Q744 E748Q744-V746 PolarHBondContact O-N 3.18Å; V746-E748 PolarHBondContact O-N 3.28Å
747V33.8Very low36.6Very low147 Ų147146 Ų14689%0.89174%0.739SS**SBendtrans-65.184.8179.1-1780000108.7
748E34.8Very low36Very low168 Ų168151 Ų15179%0.78576%0.76SS**  trans-118.1134.2164-73.9-176.5173.300107.1V746V746-E748 PolarHBondContact O-N 3.28Å
749Q29.3Very low35.3Very low185 Ų185143.6 Ų143.686%0.86475%0.754SS**  trans-57.3140.2-159.5-70.5162.8-22.500113.6V751Q749-V751 PolarHBondContact O-N 2.72Å
750A26.6Very low34.8Very low103 Ų103149.2 Ų149.285%0.85178%0.778SS**  trans-17.1107.4163.500000116.6
751V29.1Very low34.3Very low129 Ų129157.8 Ų157.878%0.78280%0.802SS**  trans-127.695.4155.7-176.60000108.5Q749Q749-V751 PolarHBondContact O-N 2.72Å
752S28.2Very low33.9Very low94 Ų94156.1 Ų156.166%0.65780%0.801SS**  trans25.6106.4146.844.80000117.9
753L26.9Very low34.3Very low170 Ų170154 Ų15489%0.8980%0.797SS**  29.589.388.3-78.4161.4000113.6
754Q27.1Very low34.5Very low184 Ų184155.4 Ų155.486%0.8680%0.802SS**  trans-173.826.2148.4-112.7175.615.400120.9
755K27.5Very low35.2Very low207 Ų207153 Ų15390%0.980%0.802SS**SBendtrans-126.786.9168.6-73-173.7179.41760113.3
756R26.8Very low36.1Very low229 Ų229154.4 Ų154.486%0.86480%0.799SS**  trans49.5103.7133.7-65175.9176.3178.1-2.9115.3
757Q28.2Very low37.1Very low197 Ų197152.5 Ų152.592%0.92179%0.788SS**  37.582.283.1-70.2-1680.700113.9
758E32.9Very low38.4Very low200 Ų200149.3 Ų149.394%0.93577%0.768SS**  trans-122.795.8145.7-80.9-175.4172.400107.1
759G31.7Very low39.4Very low71 Ų71146.8 Ų146.873%0.73276%0.76SS**  trans-105122.7-178.300000111
760Q35.4Very low40.8Very low197 Ų197144.6 Ų144.692%0.92175%0.75SS**  trans-141.7107.6148.4-82.4-172.9-2.500107.9
761R40.4Very low42.5Very low243 Ų243143.3 Ų143.392%0.91773%0.731SS**PPolyproline II helixtrans-88.9136.2170.4-81.1-178.9174.8178.3-0.8108.8
762P40.8Very low44.2Very low115 Ų115142.8 Ų142.875%0.74772%0.722SS**PPolyproline II helixtrans-65.4145.7176.924.2-30.8000111.9
763K53.8Low45.6Very low168 Ų168147.5 Ų147.573%0.7373%0.725SS**PPolyproline II helixtrans-73.1137.6-175.5-69-179.3179.1178.40111.1A765 D766K763-A765 PolarHBondContact O-N 2.7Å; K763-A765 VanDerWaalsContact O-N 3.12Å; K763-D766 PolarHBondContact O-N 3.39Å
764M51.7Low47Very low152 Ų152144.8 Ų144.875%0.74971%0.711SS**Hα-helixtrans-56.6-28.8-177.6-163.570.8145.900113.8D766 V767 V768M764-D766 VanDerWaalsContact C-N 3.3Å; M764-D766 PolarHBondContact O-N 2.9Å; M764-V767 PolarHBondContact O-N 3.38Å; M764-V768 WeakPolarHBondContact O-CG2 3.32Å; M764-V768 PolarHBondContact O-N 3.37Å
765A61.1Low48.6Very low63 Ų63144.2 Ų144.252%0.52170%0.701SS.*Hα-helixtrans-60.9-36.7179.500000113K763 V767 V768 N769K763-A765 PolarHBondContact O-N 2.7Å; K763-A765 VanDerWaalsContact O-N 3.12Å; A765-V767 VanDerWaalsContact C-N 3.34Å; A765-V767 PolarHBondContact O-N 2.92Å; A765-V768 PolarHBondContact O-N 3.43Å; A765-N769 PolarHBondContact O-N 3.04Å; A765-N769 VanDerWaalsContact O-N 3.15Å
766D55.9Low49.9Very low105 Ų105142.9 Ų142.956%0.56169%0.69SS**Hα-helixtrans-69.6-36.1-179.4-62.8-34.7000111.3K763 M764 Q770K763-D766 PolarHBondContact O-N 3.39Å; M764-D766 VanDerWaalsContact C-N 3.3Å; M764-D766 PolarHBondContact O-N 2.9Å; D766-Q770 PolarHBondContact O-N 3.31Å
767V56.6Low51.4Low76 Ų76136.3 Ų136.346%0.46167%0.671SS.*Hα-helixtrans-66.9-43.3176.9-177.70000110.8M764 A765 Q770 V771M764-V767 PolarHBondContact O-N 3.38Å; A765-V767 VanDerWaalsContact C-N 3.34Å; A765-V767 PolarHBondContact O-N 2.92Å; V767-Q770 PolarHBondContact O-N 2.75Å; V767-V771 WeakPolarHBondContact O-CG2 3.46Å; V767-V771 PolarHBondContact O-N 3.28Å; V767-V771 VanDerWaalsContact O-N 3.16Å
768V61.1Low52.5Low80 Ų80133.6 Ų133.649%0.48566%0.658SS.*Hα-helixtrans-65.2-42.4-179.5174.60000111.5M764 A765 Q770 V771 M772M764-V768 WeakPolarHBondContact O-CG2 3.32Å; M764-V768 PolarHBondContact O-N 3.37Å; A765-V768 PolarHBondContact O-N 3.43Å; V768-Q770 VanDerWaalsContact C-N 3.3Å; V768-Q770 PolarHBondContact O-N 3.34Å; V768-V771 PolarHBondContact O-N 2.87Å; V768-M772 WeakPolarHBondContact O-CG 3.28Å; V768-M772 PolarHBondContact O-N 3.16Å
769N56.5Low53.6Low114 Ų114130.2 Ų130.261%0.6164%0.642SS**Hα-helixtrans-62.7-36.7177.4-83.9-21.4000112.5A765 R773A765-N769 PolarHBondContact O-N 3.04Å; A765-N769 VanDerWaalsContact O-N 3.15Å; N769-R773 PolarHBondContact O-N 3.33Å
770Q57.6Low54.9Low140 Ų140131.3 Ų131.365%0.65463%0.632SS**Hα-helixtrans-68.2-39.9177.9-135.11769.400112.2D766 V767 V768 R773 L774D766-Q770 PolarHBondContact O-N 3.31Å; V767-Q770 PolarHBondContact O-N 2.75Å; V768-Q770 VanDerWaalsContact C-N 3.3Å; V768-Q770 PolarHBondContact O-N 3.34Å; Q770-R773 PolarHBondContact O-N 2.82Å; Q770-L774 WeakPolarHBondContact O-CG 3.47Å; Q770-L774 PolarHBondContact O-N 2.78Å
771V62.6Low55.5Low76 Ų76127 Ų12746%0.46161%0.614SS.*Hα-helixtrans-66.6-41.5177.6173.30000111.6V767 V768 R773 L774 R775V767-V771 WeakPolarHBondContact O-CG2 3.46Å; V767-V771 PolarHBondContact O-N 3.28Å; V767-V771 VanDerWaalsContact O-N 3.16Å; V768-V771 PolarHBondContact O-N 2.87Å; V771-R773 VanDerWaalsContact C-N 3.32Å; V771-R773 PolarHBondContact O-N 3.22Å; V771-L774 PolarHBondContact O-N 3.25Å; V771-R775 PolarHBondContact O-N 2.88Å; V771-R775 VanDerWaalsContact O-N 3.12Å
772M66.4Low56Low118 Ų118120.4 Ų120.458%0.58160%0.601SS**Hα-helixtrans-62.5-39.1177.2-75.9-76-98.100112V768 R775 R776V768-M772 WeakPolarHBondContact O-CG 3.28Å; V768-M772 PolarHBondContact O-N 3.16Å; M772-R775 PolarHBondContact O-N 3.09Å; M772-R776 PolarHBondContact O-N 3.14Å
773R55.8Low56.3Low193 Ų193123 Ų12373%0.72860%0.6SS**Hα-helixtrans-65.8-39.5178-156.8178.7-172.5-155.72.1112.2N769 Q770 V771 R776 I777N769-R773 PolarHBondContact O-N 3.33Å; Q770-R773 PolarHBondContact O-N 2.82Å; V771-R773 VanDerWaalsContact C-N 3.32Å; V771-R773 PolarHBondContact O-N 3.22Å; R773-R776 PolarHBondContact O-N 2.86Å; R773-I777 WeakPolarHBondContact O-CG1 3.15Å; R773-I777 PolarHBondContact O-N 3.37Å
774L57.9Low56Low113 Ų113121.1 Ų121.159%0.59260%0.598SS**Hα-helixtrans-67.7-39.3177.9-74166.5000112.6Q770 V771 R776 I777 Q778Q770-L774 WeakPolarHBondContact O-CG 3.47Å; Q770-L774 PolarHBondContact O-N 2.78Å; V771-L774 PolarHBondContact O-N 3.25Å; L774-R776 VanDerWaalsContact C-N 3.33Å; L774-R776 PolarHBondContact O-N 2.99Å; L774-I777 PolarHBondContact O-N 2.98Å; L774-Q778 PolarHBondContact O-N 2.75Å
775R59.4Low55.7Low172 Ų172120.6 Ų120.665%0.64960%0.599SS**Hα-helixtrans-62.9-38.1175.6-84.5-172.5177.2-177.1-0.3112.8V771 M772 Q778 Q779V771-R775 PolarHBondContact O-N 2.88Å; V771-R775 VanDerWaalsContact O-N 3.12Å; M772-R775 PolarHBondContact O-N 3.09Å; R775-Q778 PolarHBondContact O-N 2.96Å; R775-Q779 PolarHBondContact O-N 3.33Å; R775-Q779 VanDerWaalsContact O-N 3.16Å
776R55.6Low54.6Low179 Ų179121.1 Ų121.168%0.67561%0.61SS**Hα-helixtrans-65.7-43.6-180-155.3-180-76.1-179.6-4.6111.4M772 R773 L774 Q778 Q779 D780M772-R776 PolarHBondContact O-N 3.14Å; R773-R776 PolarHBondContact O-N 2.86Å; L774-R776 VanDerWaalsContact C-N 3.33Å; L774-R776 PolarHBondContact O-N 2.99Å; R776-Q778 VanDerWaalsContact C-N 3.27Å; R776-Q778 PolarHBondContact O-N 3.07Å; R776-Q779 PolarHBondContact O-N 2.93Å; R776-D780 PolarHBondContact O-N 2.85Å; R776-D780 VanDerWaalsContact O-N 3.15Å
777I58Low53.5Low91 Ų91120.6 Ų120.647%0.46761%0.614SS.*Hα-helixtrans-60.5-37.6175.1-64.6166.8000111.4R773 L774 D780 I781R773-I777 WeakPolarHBondContact O-CG1 3.15Å; R773-I777 PolarHBondContact O-N 3.37Å; L774-I777 PolarHBondContact O-N 2.98Å; I777-D780 PolarHBondContact O-N 2.52Å; I777-I781 HydrophobicContact CG2-CD1 4.07Å; I777-I781 WeakPolarHBondContact O-CG1 3.2Å; I777-I781 PolarHBondContact O-N 3.07Å
778Q50.7Low52.7Low139 Ų139127.2 Ų127.265%0.6566%0.655SS**Hα-helixtrans-70.1-32.3-179.6-137.6173.4-1.700112.9L774 R775 R776 T782L774-Q778 PolarHBondContact O-N 2.75Å; R775-Q778 PolarHBondContact O-N 2.96Å; R776-Q778 VanDerWaalsContact C-N 3.27Å; R776-Q778 PolarHBondContact O-N 3.07Å; Q778-T782 PolarHBondContact O-N 2.87Å; Q778-T782 PolarHBondContact O-OG1 2.94Å
779Q57.7Low52.3Low129 Ų129129.6 Ų129.660%0.60366%0.663SS**Hα-helixtrans-74.2-33.4175.3-76.3-177.7-23.500112.9R775 R776 I781 T782 K783R775-Q779 PolarHBondContact O-N 3.33Å; R775-Q779 VanDerWaalsContact O-N 3.16Å; R776-Q779 PolarHBondContact O-N 2.93Å; Q779-I781 VanDerWaalsContact C-N 3.34Å; Q779-T782 PolarHBondContact O-N 3.45Å; Q779-T782 PolarHBondContact O-OG1 2.9Å; Q779-K783 PolarHBondContact O-N 3.36Å
780D57.3Low52Low95 Ų95130.4 Ų130.451%0.50867%0.666SS.*Hα-helixtrans-69.9-33.8177.3-69-24.2000111.6R776 I777 K783 N784R776-D780 PolarHBondContact O-N 2.85Å; R776-D780 VanDerWaalsContact O-N 3.15Å; I777-D780 PolarHBondContact O-N 2.52Å; D780-K783 PolarHBondContact O-N 3.33Å; D780-N784 PolarHBondContact O-N 3.14Å
781I49.2Very low51.7Low105 Ų105129.9 Ų129.954%0.53867%0.667SS.*Hα-helixtrans-68.6-35.4176.5-66.1166.5000111.8I777 Q779I777-I781 HydrophobicContact CG2-CD1 4.07Å; I777-I781 WeakPolarHBondContact O-CG1 3.2Å; I777-I781 PolarHBondContact O-N 3.07Å; Q779-I781 VanDerWaalsContact C-N 3.34Å
782T50.9Low51.1Low105 Ų105133.1 Ų133.164%0.64468%0.679SS**Hα-helixtrans-75.9-27178.539.40000113.4Q778 Q779Q778-T782 PolarHBondContact O-N 2.87Å; Q778-T782 PolarHBondContact O-OG1 2.94Å; Q779-T782 PolarHBondContact O-N 3.45Å; Q779-T782 PolarHBondContact O-OG1 2.9Å
783K47Very low50.1Low169 Ų169134 Ų13474%0.73569%0.685SS**Hα-helixtrans-74.5-35175.9-81.8-173.9174.9-177.60113.5Q779 D780 N785 G786Q779-K783 PolarHBondContact O-N 3.36Å; D780-K783 PolarHBondContact O-N 3.33Å; K783-N785 VanDerWaalsContact C-N 3.29Å; K783-N785 PolarHBondContact O-N 3.26Å; K783-G786 PolarHBondContact O-N 3.39Å
784N46.9Very low49.8Very low130 Ų130130.1 Ų130.170%0.69568%0.682SS**THydrogen-bonded Turntrans-77.7-7.9-177-80.4-3.1000115D780D780-N784 PolarHBondContact O-N 3.14Å
785N44.7Very low49.2Very low141 Ų141131.3 Ų131.375%0.75469%0.688SS**THydrogen-bonded Turntrans-93.75.9176.1-76.6-10.4000113.8K783K783-N785 VanDerWaalsContact C-N 3.29Å; K783-N785 PolarHBondContact O-N 3.26Å
786G39.3Very low48.4Very low73 Ų73128.2 Ų128.275%0.75369%0.691SS**SBendtrans-98.73.9-179.800000115.4K783K783-G786 PolarHBondContact O-N 3.39Å
787S33.2Very low47.8Very low94 Ų94123.9 Ų123.966%0.65769%0.693SS**  trans-129.965.2-17661.80000112.2
788V38.7Very low46.9Very low216 Ų216126.9 Ų126.9100%1.30971%0.713SS**  trans-145.10152.2-177.10000108.3

Retrieved 788 of 788 residues in 565.2 ms (Link to these results)