A0A077Z0V3_TRITR Loading...

Aldehyde dehydrogenase, mitochondrial

AlphaFold DB , UniProt , Accession A0A077Z0V3, Species TRITR (Trichuris trichiura, Whipworm), Gene n/a, Length 518 aa.

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Site Residue pLDDT pLDDT confidence pLDDT10 pLDDT10 confidence SASA SASA [Ų] SASA10 SASA10 [Ų] RSA RSA unformatted RSA10 RSA10 unformatted Surface Surface10 (not used) Disorder (not used) Disorder Sec. str. Secondary structure Isomer Phi (φ) Psi (ψ) Omega (ω) Chi 1 (χ1) Chi 2 (χ2) Chi 3 (χ3) Chi 4 (χ4) Chi 5 (χ5) Tau (τ) Contacts (colored by PAE) Contact details
1M96.6Very high96.5Very high11 Ų1154.3 Ų54.35%0.05428%0.28CS..  0162.70-56.6172.8-71.900109.3W7 I8 D9 S10 Q31 A33 D37 P228M1-W7 WeakPolarHBondContact O-CA 3.45Å; M1-W7 VanDerWaalsContact O-CE3 3.28Å; M1-I8 PolarHBondContact N-O 2.82Å; M1-I8 PolarHBondContact O-N 3.41Å; M1-D9 VanDerWaalsContact CE-C 3.45Å; M1-D9 WeakPolarHBondContact CE-O 3.3Å; M1-S10 VanDerWaalsContact CE-CA 3.49Å; M1-Q31 HydrophobicContact CG-CB 4.03Å; M1-A33 HydrophobicContact CG-CB 4.43Å; M1-A33 HydrophobicContact SD-CB 3.41Å; M1-A33 WeakPolarHBondContact SD-CB 3.33Å; M1-D37 HydrophobicContact CE-CB 3.98Å; M1-D37 HydrophobicContact SD-CB 3.76Å; M1-P228 HydrophobicContact CG-CG 4.29Å
2F98Very high96.5Very high0 Ų057.2 Ų57.20%030%0.296CS..EExtended strand (participates in β ladder)trans-115.1107.2177.4-178.8-99.2000109.7N5 E6 W7 G184 A188 N225 I226F2-N5 HydrophobicContact CZ-CB 4.25Å; F2-E6 WeakPolarHBondContact CA-O 3.31Å; F2-W7 HydrophobicContact CB-CE3 4.25Å; F2-W7 HydrophobicContact CB-CH2 4.21Å; F2-W7 HydrophobicContact CB-CZ3 3.91Å; F2-W7 HydrophobicContact CD2-CD2 4.36Å; F2-W7 HydrophobicContact CD2-CH2 4.33Å; F2-W7 HydrophobicContact CD2-CZ2 4.12Å; F2-G184 WeakPolarHBondContact CE2-O 3.43Å; F2-G184 WeakPolarHBondContact CZ-O 3.36Å; F2-A188 HydrophobicContact CE2-CB 3.94Å; F2-A188 HydrophobicContact CZ-CB 3.99Å; F2-N225 CarbonylContact O-C 3.56Å; F2-N225 WeakPolarHBondContact O-CA 3.35Å; F2-I226 HydrophobicContact CB-CB 4.2Å; F2-I226 HydrophobicContact CB-CG1 4.47Å; F2-I226 HydrophobicContact CD1-CG1 4.36Å; F2-I226 PolarHBondContact N-O 2.67Å; F2-I226 PolarHBondContact O-N 3.44Å
3I97.7Very high96.5Very high0 Ų056.9 Ų56.90%032%0.316CS..EExtended strand (participates in β ladder)trans-135.6134-176.8-61.7173.2000107.8N5 E6 I8 K40 A41 A44 V227I3-N5 VanDerWaalsContact C-N 3.26Å; I3-N5 PolarHBondContact O-N 3.01Å; I3-E6 PolarHBondContact N-O 3.25Å; I3-E6 PolarHBondContact O-N 3.34Å; I3-I8 HydrophobicContact CB-CD1 3.86Å; I3-I8 HydrophobicContact CB-CG1 4.48Å; I3-I8 HydrophobicContact CG2-CD1 4.34Å; I3-K40 HydrophobicContact CG2-CG 4.32Å; I3-A41 HydrophobicContact CD1-CB 4.07Å; I3-A41 HydrophobicContact CG1-CB 4.13Å; I3-A41 HydrophobicContact CG2-CB 4.42Å; I3-A44 HydrophobicContact CG2-CB 4.3Å; I3-V227 HydrophobicContact CD1-CG1 4.07Å; I3-V227 HydrophobicContact CG1-CG1 4.29Å
4D95.1Very high96.6Very high65 Ų6554.8 Ų54.835%0.34831%0.307SS..THydrogen-bonded Turntrans57.336.1177.5-151.229.4000114.2E6 A44 P221 G222 N225D4-E6 PolarHBondContact O-N 3.41Å; D4-A44 HydrophobicContact CB-CB 4.19Å; D4-P221 WeakPolarHBondContact OD1-CA 3.44Å; D4-P221 WeakPolarHBondContact OD1-CB 3.46Å; D4-G222 PolarHBondContact OD1-N 3.44Å; D4-N225 PolarHBondContact N-OD1 2.8Å; D4-N225 VanDerWaalsContact N-OD1 3.16Å
5N93.6Very high96.7Very high36 Ų3654.7 Ų54.719%0.19331%0.312CS..THydrogen-bonded Turntrans61.516.1-171.3-67.6-7.6000115.6F2 I3 F219 P221F2-N5 HydrophobicContact CZ-CB 4.25Å; I3-N5 VanDerWaalsContact C-N 3.26Å; I3-N5 PolarHBondContact O-N 3.01Å; N5-F219 PolarHBondContact ND2-O 3.05Å; N5-F219 VanDerWaalsContact ND2-O 3.09Å; N5-P221 HydrophobicContact CB-CB 4.5Å
6E95.2Very high96.8Very high124 Ų12451.6 Ų51.658%0.57929%0.293SS*.EExtended strand (participates in β ladder)trans-117.8153.4177.7-62.7-172.1159.700112.4F2 I3 D4 I8F2-E6 WeakPolarHBondContact CA-O 3.31Å; I3-E6 PolarHBondContact N-O 3.25Å; I3-E6 PolarHBondContact O-N 3.34Å; D4-E6 PolarHBondContact O-N 3.41Å; E6-I8 HydrophobicContact CB-CD1 4.43Å; E6-I8 HydrophobicContact CB-CG1 4.2Å
7W97.3Very high96.9Very high145 Ų14551.1 Ų51.155%0.54929%0.293SS..EExtended strand (participates in β ladder)trans-88.2119.7170.4-68.2107.4000109.8M1 F2 L181M1-W7 WeakPolarHBondContact O-CA 3.45Å; M1-W7 VanDerWaalsContact O-CE3 3.28Å; F2-W7 HydrophobicContact CB-CE3 4.25Å; F2-W7 HydrophobicContact CB-CH2 4.21Å; F2-W7 HydrophobicContact CB-CZ3 3.91Å; F2-W7 HydrophobicContact CD2-CD2 4.36Å; F2-W7 HydrophobicContact CD2-CH2 4.33Å; F2-W7 HydrophobicContact CD2-CZ2 4.12Å; W7-L181 HydrophobicContact CH2-CB 4.17Å; W7-L181 HydrophobicContact CH2-CD2 4.49Å; W7-L181 WeakPolarHBondContact CH2-O 3.49Å; W7-L181 HydrophobicContact CZ3-CB 4.41Å; W7-L181 HydrophobicContact CZ3-CD2 4.01Å
8I96.1Very high96.9Very high33 Ų3348.3 Ų48.317%0.16928%0.277CS..  trans-128.9137.7-173.6-40.9-170.8000109.9M1 I3 E6 K40M1-I8 PolarHBondContact N-O 2.82Å; M1-I8 PolarHBondContact O-N 3.41Å; I3-I8 HydrophobicContact CB-CD1 3.86Å; I3-I8 HydrophobicContact CB-CG1 4.48Å; I3-I8 HydrophobicContact CG2-CD1 4.34Å; E6-I8 HydrophobicContact CB-CD1 4.43Å; E6-I8 HydrophobicContact CB-CG1 4.2Å; I8-K40 HydrophobicContact CD1-CD 4.47Å
9D97.7Very high97Very high109 Ų10949.1 Ų49.158%0.58328%0.279SS*.  trans-73.3158.7169.4-67.3-30.4000111.7M1 Q31M1-D9 VanDerWaalsContact CE-C 3.45Å; M1-D9 WeakPolarHBondContact CE-O 3.3Å; D9-Q31 PolarHBondContact OD1-NE2 3.41Å
10S97.6Very high97.1Very high8 Ų847.9 Ų47.96%0.05627%0.272CS..  trans-62.4143.4176.453.60000110.8M1 D12 G13 S14 Q31 E32M1-S10 VanDerWaalsContact CE-CA 3.49Å; S10-D12 PolarHBondContact O-N 3.27Å; S10-D12 VanDerWaalsContact O-N 3.09Å; S10-G13 PolarHBondContact O-N 3.5Å; S10-G13 VanDerWaalsContact OG-CA 3.25Å; S10-G13 WeakPolarHBondContact OG-CA 3.38Å; S10-G13 PolarHBondContact OG-N 2.99Å; S10-S14 WeakPolarHBondContact CB-O 3.48Å; S10-S14 PolarHBondContact OG-N 3.06Å; S10-S14 PolarHBondContact OG-O 3.1Å; S10-Q31 PolarHBondContact OG-OE1 3.17Å; S10-E32 VanDerWaalsContact CB-O 3.26Å; S10-E32 WeakPolarHBondContact CB-O 3.24Å
11A96.9Very high97.1Very high66 Ų6645.6 Ų45.655%0.54526%0.259SS..THydrogen-bonded Turntrans-60.8-22.6-17600000113.9K36 D37A11-K36 HydrophobicContact CB-CB 4.01Å; A11-K36 HydrophobicContact CB-CD 4.38Å; A11-D37 VanDerWaalsContact CB-OD1 3.27Å; A11-D37 WeakPolarHBondContact CB-OD1 3.14Å; A11-D37 PolarHBondContact N-OD1 2.97Å
12D96Very high97.2Very high89 Ų8946 Ų4648%0.47626%0.262SS..THydrogen-bonded Turntrans-107.62.7174.872.7-9.9000113.8S10 S14 K34S10-D12 PolarHBondContact O-N 3.27Å; S10-D12 VanDerWaalsContact O-N 3.09Å; D12-S14 VanDerWaalsContact C-N 3.31Å; D12-S14 PolarHBondContact O-N 2.78Å; D12-S14 PolarHBondContact OD1-N 3.36Å; D12-S14 PolarHBondContact OD1-OG 3.15Å; D12-K34 IonicContact OD1-NZ 2.64Å; D12-K34 VanDerWaalsContact OD2-CD 3.31Å; D12-K34 WeakPolarHBondContact OD2-CD 3.4Å; D12-K34 WeakPolarHBondContact OD2-CE 3.4Å; D12-K34 IonicContact OD2-NZ 2.77Å; D12-K34 PolarHBondContact OD2-NZ 3.46Å
13G96.7Very high97.2Very high54 Ų5448.3 Ų48.356%0.55728%0.276SS*.  trans75.38179.600000115.3S10S10-G13 PolarHBondContact O-N 3.5Å; S10-G13 VanDerWaalsContact OG-CA 3.25Å; S10-G13 WeakPolarHBondContact OG-CA 3.38Å; S10-G13 PolarHBondContact OG-N 2.99Å
14S97.5Very high97.1Very high27 Ų2749.8 Ų49.819%0.18929%0.291CS..  trans-75.9150177.778.60000113.3S10 D12 Q31 E32 K34S10-S14 WeakPolarHBondContact CB-O 3.48Å; S10-S14 PolarHBondContact OG-N 3.06Å; S10-S14 PolarHBondContact OG-O 3.1Å; D12-S14 VanDerWaalsContact C-N 3.31Å; D12-S14 PolarHBondContact O-N 2.78Å; D12-S14 PolarHBondContact OD1-N 3.36Å; D12-S14 PolarHBondContact OD1-OG 3.15Å; S14-Q31 PolarHBondContact O-OE1 3.18Å; S14-E32 WeakPolarHBondContact CB-OE2 3.33Å; S14-E32 PolarHBondContact O-N 3.39Å; S14-E32 WeakPolarHBondContact OG-CB 3.47Å; S14-E32 PolarHBondContact OG-OE2 2.92Å; S14-K34 VanDerWaalsContact OG-CE 3.24Å; S14-K34 WeakPolarHBondContact OG-CE 3.22Å; S14-K34 PolarHBondContact OG-NZ 3.34Å
15S98.2Very high97.2Very high54 Ų5451.1 Ų51.138%0.37830%0.299SS..EExtended strand (participates in β ladder)trans-141.5159.4176.260.20000110V30S15-V30 CarbonylContact C-O 3.57Å; S15-V30 WeakPolarHBondContact CA-O 3.4Å; S15-V30 VanDerWaalsContact CB-O 3.26Å; S15-V30 WeakPolarHBondContact CB-O 3.4Å
16F98.3Very high97.4Very high4 Ų453.4 Ų53.42%0.01831%0.31CS..EExtended strand (participates in β ladder)trans-128.3149.5177.767.2-87.6000110.8Y29 V30 E32 E174 P177 P228 Y230F16-Y29 WeakPolarHBondContact O-CA 3.48Å; F16-V30 WeakPolarHBondContact CD1-O 3.46Å; F16-V30 HydrophobicContact CE1-CB 4Å; F16-V30 HydrophobicContact CE1-CG1 4.01Å; F16-V30 HydrophobicContact CE2-CB 4.21Å; F16-V30 HydrophobicContact CZ-CB 3.8Å; F16-V30 HydrophobicContact CZ-CG1 3.9Å; F16-V30 PolarHBondContact N-O 3.41Å; F16-V30 PolarHBondContact O-N 3Å; F16-E32 HydrophobicContact CD1-CB 3.83Å; F16-E32 HydrophobicContact CD1-CG 4.11Å; F16-E32 HydrophobicContact CE1-CB 4.5Å; F16-E174 HydrophobicContact CE2-CB 4.18Å; F16-E174 WeakPolarHBondContact CE2-O 3.4Å; F16-P177 HydrophobicContact CE2-CG 4.22Å; F16-P177 HydrophobicContact CZ-CB 4.46Å; F16-P177 HydrophobicContact CZ-CG 4.2Å; F16-P228 HydrophobicContact CE1-CB 4.19Å; F16-P228 HydrophobicContact CZ-CB 4.05Å; F16-Y230 HydrophobicContact CB-CE2 3.93Å; F16-Y230 HydrophobicContact CG-CE2 4.43Å
17P98.3Very high97.6Very high44 Ų4449.9 Ų49.929%0.28630%0.295SS..EExtended strand (participates in β ladder)trans-77.2136.1176.531.2-33.1000110.8I26 C28 Y29P17-I26 HydrophobicContact CB-CD1 3.99Å; P17-I26 HydrophobicContact CB-CG1 3.99Å; P17-I26 HydrophobicContact CB-CG2 3.84Å; P17-C28 WeakPolarHBondContact CA-O 3.27Å; P17-Y29 HydrophobicContact CB-CD1 4.39Å; P17-Y29 HydrophobicContact CB-CE1 4.09Å; P17-Y29 HydrophobicContact CG-CE1 4.48Å
18T97.8Very high97.6Very high1 Ų145.3 Ų45.31%0.00628%0.284CS..EExtended strand (participates in β ladder)trans-90.3142.5155.4172.90000109.3I26 I27 C28 V30 D88 L178T18-I26 WeakPolarHBondContact O-CA 3.48Å; T18-I27 HydrophobicContact CG2-CB 4.03Å; T18-I27 PolarHBondContact O-N 2.85Å; T18-C28 WeakPolarHBondContact CG2-O 3.15Å; T18-C28 VanDerWaalsContact CG2-SG 3.51Å; T18-C28 PolarHBondContact N-O 3.03Å; T18-V30 HydrophobicContact CG2-CG2 4.35Å; T18-D88 PolarHBondContact OG1-OD1 3.47Å; T18-L178 HydrophobicContact CG2-CD1 4.15Å; T18-L178 HydrophobicContact CG2-CD2 4.01Å; T18-L178 HydrophobicContact CG2-CG 4.21Å
19I98.4Very high97.8Very high63 Ų6350.8 Ų50.832%0.32330%0.304SS..EExtended strand (participates in β ladder)trans-122.7131.5-168.7-61.2172.9000109P21 D25I19-P21 VanDerWaalsContact O-CD 3.24Å; I19-P21 WeakPolarHBondContact O-CD 3.33Å; I19-D25 CarbonylContact C-O 3.57Å; I19-D25 WeakPolarHBondContact CA-O 3.26Å
20N98.4Very high97.8Very high24 Ų2446.1 Ų46.113%0.12828%0.279CS..  trans-72114.3171.4-179.5-18000109.1T22 T23 G24 D25 I27 L87N20-T22 PolarHBondContact O-N 3.43Å; N20-T22 VanDerWaalsContact O-N 3.11Å; N20-T22 WeakPolarHBondContact OD1-CB 3.49Å; N20-T22 PolarHBondContact OD1-N 2.74Å; N20-T22 PolarHBondContact OD1-OG1 3.1Å; N20-T23 PolarHBondContact O-N 2.79Å; N20-G24 WeakPolarHBondContact O-CA 3.38Å; N20-G24 PolarHBondContact O-N 3.12Å; N20-D25 PolarHBondContact N-O 2.83Å; N20-I27 HydrophobicContact CB-CD1 3.98Å; N20-I27 HydrophobicContact CB-CG1 3.76Å; N20-L87 WeakPolarHBondContact ND2-CD1 3.19Å
21P98.5Very high97.8Very high0 Ų048.1 Ų48.10%029%0.288CS..THydrogen-bonded Turntrans-66-16.6-177.125.5-34.2000114.3I19 N89 P349 Q350 I351 G384 Y385I19-P21 VanDerWaalsContact O-CD 3.24Å; I19-P21 WeakPolarHBondContact O-CD 3.33Å; P21-N89 WeakPolarHBondContact CG-O 3.45Å; P21-P349 VanDerWaalsContact C-CG 3.49Å; P21-P349 HydrophobicContact CB-CB 4.2Å; P21-P349 HydrophobicContact CB-CG 3.69Å; P21-P349 HydrophobicContact CG-CG 3.93Å; P21-P349 VanDerWaalsContact O-CB 3.3Å; P21-P349 WeakPolarHBondContact O-CB 3.16Å; P21-P349 WeakPolarHBondContact O-CG 3.4Å; P21-Q350 VanDerWaalsContact CB-O 3.22Å; P21-Q350 WeakPolarHBondContact CB-O 3.47Å; P21-I351 WeakPolarHBondContact CB-O 3.26Å; P21-G384 CarbonylContact O-C 3.5Å; P21-G384 WeakPolarHBondContact O-CA 3.39Å; P21-Y385 HydrophobicContact CB-CD2 3.74Å; P21-Y385 HydrophobicContact CB-CE2 4.21Å; P21-Y385 PolarHBondContact O-N 2.91Å
22T98.2Very high97.9Very high20 Ų2045.9 Ų45.912%0.12327%0.266CS..THydrogen-bonded Turntrans-76.4-36.7-178.9-52.90000111.4N20 P340 G384 F386N20-T22 PolarHBondContact O-N 3.43Å; N20-T22 VanDerWaalsContact O-N 3.11Å; N20-T22 WeakPolarHBondContact OD1-CB 3.49Å; N20-T22 PolarHBondContact OD1-N 2.74Å; N20-T22 PolarHBondContact OD1-OG1 3.1Å; T22-P340 HydrophobicContact CG2-CG 4.43Å; T22-P340 WeakPolarHBondContact OG1-CD 3.48Å; T22-P340 WeakPolarHBondContact OG1-CG 3.39Å; T22-G384 WeakPolarHBondContact O-CA 3.31Å; T22-G384 PolarHBondContact O-N 2.99Å; T22-F386 HydrophobicContact CG2-CE2 4.27Å; T22-F386 HydrophobicContact CG2-CZ 4.03Å
23T97.1Very high98Very high48 Ų4841.6 Ų41.629%0.29424%0.243SC..THydrogen-bonded Turntrans-112.5-26.8-175.667.90000113N20 D25N20-T23 PolarHBondContact O-N 2.79Å; T23-D25 VanDerWaalsContact C-N 3.3Å; T23-D25 WeakPolarHBondContact CB-OD2 3.17Å; T23-D25 WeakPolarHBondContact OG1-CB 3.27Å; T23-D25 VanDerWaalsContact OG1-CG 3.26Å; T23-D25 PolarHBondContact OG1-N 3.36Å; T23-D25 VanDerWaalsContact OG1-N 3.16Å; T23-D25 PolarHBondContact OG1-OD2 3.39Å
24G96.4Very high98.1Very high31 Ų3141.7 Ų41.732%0.3223%0.228SC..  trans83.73.3-169.400000113.6N20N20-G24 WeakPolarHBondContact O-CA 3.38Å; N20-G24 PolarHBondContact O-N 3.12Å
25D97.5Very high98.1Very high93 Ų9344.6 Ų44.650%0.49724%0.239SC..  trans-83.1151.1-179.1-55.9-46.8000111.5I19 N20 T23 I27I19-D25 CarbonylContact C-O 3.57Å; I19-D25 WeakPolarHBondContact CA-O 3.26Å; N20-D25 PolarHBondContact N-O 2.83Å; T23-D25 VanDerWaalsContact C-N 3.3Å; T23-D25 WeakPolarHBondContact CB-OD2 3.17Å; T23-D25 WeakPolarHBondContact OG1-CB 3.27Å; T23-D25 VanDerWaalsContact OG1-CG 3.26Å; T23-D25 PolarHBondContact OG1-N 3.36Å; T23-D25 VanDerWaalsContact OG1-N 3.16Å; T23-D25 PolarHBondContact OG1-OD2 3.39Å; D25-I27 PolarHBondContact O-N 3.41Å
26I98.3Very high98.1Very high85 Ų8549.7 Ų49.744%0.43625%0.254SS..EExtended strand (participates in β ladder)trans-70.4127.3173.3-61.5173.8000108.9P17 T18 Y29P17-I26 HydrophobicContact CB-CD1 3.99Å; P17-I26 HydrophobicContact CB-CG1 3.99Å; P17-I26 HydrophobicContact CB-CG2 3.84Å; T18-I26 WeakPolarHBondContact O-CA 3.48Å; I26-Y29 HydrophobicContact CD1-CE2 4.36Å; I26-Y29 HydrophobicContact CG2-CD2 4.33Å; I26-Y29 HydrophobicContact CG2-CE2 4.03Å
27I98.4Very high98.1Very high50 Ų5049.8 Ų49.826%0.25626%0.255SS..EExtended strand (participates in β ladder)trans-78.1-55.4173.4-60.6158.6000109.4T18 N20 D25 L87 L178T18-I27 HydrophobicContact CG2-CB 4.03Å; T18-I27 PolarHBondContact O-N 2.85Å; N20-I27 HydrophobicContact CB-CD1 3.98Å; N20-I27 HydrophobicContact CB-CG1 3.76Å; D25-I27 PolarHBondContact O-N 3.41Å; I27-L87 HydrophobicContact CD1-CG 3.93Å; I27-L87 HydrophobicContact CG1-CD1 4.47Å; I27-L87 HydrophobicContact CG1-CD2 4.5Å; I27-L87 HydrophobicContact CG1-CG 4.19Å; I27-L87 HydrophobicContact CG2-CD2 3.85Å; I27-L87 HydrophobicContact CG2-CG 4.42Å; I27-L178 HydrophobicContact CD1-CD1 4.47Å; I27-L178 HydrophobicContact CG2-CD1 4.05Å
28C98.4Very high98.1Very high49 Ų4947.7 Ų47.733%0.33124%0.241SC..EExtended strand (participates in β ladder)trans-162.8176.817768.90000111P17 T18P17-C28 WeakPolarHBondContact CA-O 3.27Å; T18-C28 WeakPolarHBondContact CG2-O 3.15Å; T18-C28 VanDerWaalsContact CG2-SG 3.51Å; T18-C28 PolarHBondContact N-O 3.03Å
29Y98.5Very high98.2Very high147 Ų14750.7 Ų50.758%0.57626%0.257SS*.EExtended strand (participates in β ladder)trans-102.6136.6171.1-75.1-99.7000110.4F16 P17 I26F16-Y29 WeakPolarHBondContact O-CA 3.48Å; P17-Y29 HydrophobicContact CB-CD1 4.39Å; P17-Y29 HydrophobicContact CB-CE1 4.09Å; P17-Y29 HydrophobicContact CG-CE1 4.48Å; I26-Y29 HydrophobicContact CD1-CE2 4.36Å; I26-Y29 HydrophobicContact CG2-CD2 4.33Å; I26-Y29 HydrophobicContact CG2-CE2 4.03Å
30V98.5Very high98.2Very high11 Ų1152.6 Ų52.67%0.06726%0.263CS..EExtended strand (participates in β ladder)trans-118138.7178.9179.20000109.3S15 F16 T18 E32 P177 L178 L181 P228S15-V30 CarbonylContact C-O 3.57Å; S15-V30 WeakPolarHBondContact CA-O 3.4Å; S15-V30 VanDerWaalsContact CB-O 3.26Å; S15-V30 WeakPolarHBondContact CB-O 3.4Å; F16-V30 WeakPolarHBondContact CD1-O 3.46Å; F16-V30 HydrophobicContact CE1-CB 4Å; F16-V30 HydrophobicContact CE1-CG1 4.01Å; F16-V30 HydrophobicContact CE2-CB 4.21Å; F16-V30 HydrophobicContact CZ-CB 3.8Å; F16-V30 HydrophobicContact CZ-CG1 3.9Å; F16-V30 PolarHBondContact N-O 3.41Å; F16-V30 PolarHBondContact O-N 3Å; T18-V30 HydrophobicContact CG2-CG2 4.35Å; V30-E32 PolarHBondContact O-N 3.35Å; V30-P177 HydrophobicContact CB-CG 4.42Å; V30-P177 HydrophobicContact CG1-CB 4.42Å; V30-P177 HydrophobicContact CG1-CG 4.4Å; V30-P177 HydrophobicContact CG2-CG 3.87Å; V30-L178 HydrophobicContact CG2-CD2 4.08Å; V30-L181 HydrophobicContact CG1-CD1 3.81Å; V30-L181 HydrophobicContact CG2-CD1 4.42Å; V30-P228 HydrophobicContact CG1-CB 3.86Å; V30-P228 HydrophobicContact CG1-CG 3.59Å
31Q98.4Very high98.2Very high50 Ų5051.4 Ų51.423%0.23426%0.257CS..EExtended strand (participates in β ladder)trans-58129.1177.6-62.2-64.8-13.800111M1 D9 S10 S14M1-Q31 HydrophobicContact CG-CB 4.03Å; D9-Q31 PolarHBondContact OD1-NE2 3.41Å; S10-Q31 PolarHBondContact OG-OE1 3.17Å; S14-Q31 PolarHBondContact O-OE1 3.18Å
32E98.4Very high98.2Very high19 Ų1951.4 Ų51.49%0.08926%0.257CS..  trans-92.1105-176.8-171.1-163.3167.100110.4S10 S14 F16 V30 K34 Y230S10-E32 VanDerWaalsContact CB-O 3.26Å; S10-E32 WeakPolarHBondContact CB-O 3.24Å; S14-E32 WeakPolarHBondContact CB-OE2 3.33Å; S14-E32 PolarHBondContact O-N 3.39Å; S14-E32 WeakPolarHBondContact OG-CB 3.47Å; S14-E32 PolarHBondContact OG-OE2 2.92Å; F16-E32 HydrophobicContact CD1-CB 3.83Å; F16-E32 HydrophobicContact CD1-CG 4.11Å; F16-E32 HydrophobicContact CE1-CB 4.5Å; V30-E32 PolarHBondContact O-N 3.35Å; E32-K34 VanDerWaalsContact CD-CE 3.46Å; E32-K34 WeakPolarHBondContact OE1-CE 3.25Å; E32-K34 WeakPolarHBondContact OE2-CE 3.49Å; E32-K34 IonicContact OE2-NZ 3.17Å; E32-Y230 HydrophobicContact CG-CD2 4.29Å
33A98.5Very high98.2Very high0 Ų053.9 Ų53.90%028%0.275CS..  trans-68132175.700000111.2M1 D37 V227 P228 T234M1-A33 HydrophobicContact CG-CB 4.43Å; M1-A33 HydrophobicContact SD-CB 3.41Å; M1-A33 WeakPolarHBondContact SD-CB 3.33Å; A33-D37 HydrophobicContact CB-CB 4Å; A33-V227 HydrophobicContact CB-CB 3.67Å; A33-V227 HydrophobicContact CB-CG1 4.23Å; A33-P228 WeakPolarHBondContact CB-O 3.37Å; A33-P228 PolarHBondContact N-O 3.05Å; A33-T234 HydrophobicContact CB-CG2 3.71Å; A33-T234 WeakPolarHBondContact O-CB 3.17Å; A33-T234 PolarHBondContact O-OG1 2.98Å
34K98.1Very high98.3Very high56 Ų5652.2 Ų52.224%0.24327%0.266CS..  trans-118.8-168.6171.5-62.1-174.7-175.5162.80110.5D12 S14 E32 K36 D37 V38 I233D12-K34 IonicContact OD1-NZ 2.64Å; D12-K34 VanDerWaalsContact OD2-CD 3.31Å; D12-K34 WeakPolarHBondContact OD2-CD 3.4Å; D12-K34 WeakPolarHBondContact OD2-CE 3.4Å; D12-K34 IonicContact OD2-NZ 2.77Å; D12-K34 PolarHBondContact OD2-NZ 3.46Å; S14-K34 VanDerWaalsContact OG-CE 3.24Å; S14-K34 WeakPolarHBondContact OG-CE 3.22Å; S14-K34 PolarHBondContact OG-NZ 3.34Å; E32-K34 VanDerWaalsContact CD-CE 3.46Å; E32-K34 WeakPolarHBondContact OE1-CE 3.25Å; E32-K34 WeakPolarHBondContact OE2-CE 3.49Å; E32-K34 IonicContact OE2-NZ 3.17Å; K34-K36 VanDerWaalsContact C-N 3.31Å; K34-K36 PolarHBondContact O-N 2.93Å; K34-D37 PolarHBondContact N-OD2 3.12Å; K34-D37 PolarHBondContact O-N 3.18Å; K34-V38 PolarHBondContact O-N 2.8Å; K34-I233 HydrophobicContact CB-CG2 4.3Å; K34-I233 HydrophobicContact CG-CG2 4.01Å
35Q98Very high98.4Very high88 Ų8850.7 Ų50.741%0.41125%0.251SS..Hα-helixtrans-49.8-48.2-176.7-174.36556.400112.9D37 V38 D39 A237Q35-D37 VanDerWaalsContact C-N 3.3Å; Q35-D37 PolarHBondContact O-N 3.43Å; Q35-V38 PolarHBondContact O-N 3.14Å; Q35-D39 PolarHBondContact NE2-OD1 3.4Å; Q35-D39 PolarHBondContact O-N 3.12Å; Q35-A237 VanDerWaalsContact OE1-CB 3.23Å
36K98.1Very high98.4Very high160 Ų16049.2 Ų49.270%0.69624%0.238SC*.Hα-helixtrans-62.7-35.7-178.7-69-177.3180175.80113.1A11 K34 K40A11-K36 HydrophobicContact CB-CB 4.01Å; A11-K36 HydrophobicContact CB-CD 4.38Å; K34-K36 VanDerWaalsContact C-N 3.31Å; K34-K36 PolarHBondContact O-N 2.93Å; K36-K40 PolarHBondContact O-N 3.43Å; K36-K40 VanDerWaalsContact O-N 3.07Å
37D98.6Very high98.4Very high7 Ų750.1 Ų50.14%0.03724%0.243CC..Hα-helixtrans-72.8-39.5178.7-51.8-64.3000110.9M1 A11 A33 K34 Q35 K40 A41M1-D37 HydrophobicContact CE-CB 3.98Å; M1-D37 HydrophobicContact SD-CB 3.76Å; A11-D37 VanDerWaalsContact CB-OD1 3.27Å; A11-D37 WeakPolarHBondContact CB-OD1 3.14Å; A11-D37 PolarHBondContact N-OD1 2.97Å; A33-D37 HydrophobicContact CB-CB 4Å; K34-D37 PolarHBondContact N-OD2 3.12Å; K34-D37 PolarHBondContact O-N 3.18Å; Q35-D37 VanDerWaalsContact C-N 3.3Å; Q35-D37 PolarHBondContact O-N 3.43Å; D37-K40 PolarHBondContact O-N 3.41Å; D37-A41 WeakPolarHBondContact O-CB 3.09Å; D37-A41 PolarHBondContact O-N 3.18Å
38V98.7Very high98.4Very high0 Ų048.1 Ų48.10%023%0.234CC..Hα-helixtrans-62.6-44.1172175.10000110.7K34 Q35 K40 A41 V42 V227 T234 A237 V238K34-V38 PolarHBondContact O-N 2.8Å; Q35-V38 PolarHBondContact O-N 3.14Å; V38-K40 VanDerWaalsContact C-N 3.3Å; V38-K40 PolarHBondContact O-N 3.47Å; V38-A41 PolarHBondContact O-N 3.36Å; V38-V42 HydrophobicContact CG1-CG2 4.17Å; V38-V42 WeakPolarHBondContact O-CB 3.13Å; V38-V42 VanDerWaalsContact O-CG2 3.32Å; V38-V42 WeakPolarHBondContact O-CG2 3.37Å; V38-V42 PolarHBondContact O-N 2.99Å; V38-V227 HydrophobicContact CG2-CG2 4.41Å; V38-T234 HydrophobicContact CG2-CG2 3.81Å; V38-A237 HydrophobicContact CB-CB 4.13Å; V38-A237 HydrophobicContact CG1-CB 4.2Å; V38-A237 HydrophobicContact CG2-CB 3.96Å; V38-V238 HydrophobicContact CG1-CG2 3.78Å; V38-V238 HydrophobicContact CG2-CG2 4.08Å
39D98.5Very high98.3Very high63 Ų6346.2 Ų46.234%0.33722%0.223SC..Hα-helixtrans-59.1-42.8176.7-62.5-17.1000111Q35 V42 S43 H241Q35-D39 PolarHBondContact NE2-OD1 3.4Å; Q35-D39 PolarHBondContact O-N 3.12Å; D39-V42 PolarHBondContact O-N 3.26Å; D39-S43 VanDerWaalsContact O-CB 3.29Å; D39-S43 WeakPolarHBondContact O-CB 3.37Å; D39-S43 PolarHBondContact O-N 2.91Å; D39-H241 IonicContact OD1-CD2 2.85Å; D39-H241 PolarHBondContact OD1-CD2 3.17Å; D39-H241 IonicContact OD1-NE2 3.36Å; D39-H241 PolarHBondContact OD1-NE2 2.98Å
40K98.4Very high98.1Very high103 Ų10344.4 Ų44.445%0.44822%0.218SC..Hα-helixtrans-62.9-47.3175.5-172.2179.4179.7177.10111.5I3 I8 K36 D37 V38 S43 A44I3-K40 HydrophobicContact CG2-CG 4.32Å; I8-K40 HydrophobicContact CD1-CD 4.47Å; K36-K40 PolarHBondContact O-N 3.43Å; K36-K40 VanDerWaalsContact O-N 3.07Å; D37-K40 PolarHBondContact O-N 3.41Å; V38-K40 VanDerWaalsContact C-N 3.3Å; V38-K40 PolarHBondContact O-N 3.47Å; K40-S43 PolarHBondContact O-N 2.8Å; K40-A44 PolarHBondContact O-N 3.34Å
41A98.7Very high97.8Very high0 Ų049 Ų490%025%0.248CC..Hα-helixtrans-62.4-42.5178.100000112.4I3 D37 V38 A44 A45 V169 N225 V227I3-A41 HydrophobicContact CD1-CB 4.07Å; I3-A41 HydrophobicContact CG1-CB 4.13Å; I3-A41 HydrophobicContact CG2-CB 4.42Å; D37-A41 WeakPolarHBondContact O-CB 3.09Å; D37-A41 PolarHBondContact O-N 3.18Å; V38-A41 PolarHBondContact O-N 3.36Å; A41-A44 PolarHBondContact O-N 3.35Å; A41-A45 WeakPolarHBondContact O-CB 3.22Å; A41-A45 PolarHBondContact O-N 3.41Å; A41-V169 HydrophobicContact CB-CG1 3.94Å; A41-V169 HydrophobicContact CB-CG2 4.23Å; A41-N225 HydrophobicContact CB-CB 3.87Å; A41-V227 HydrophobicContact CB-CG1 3.79Å
42V98.8Very high97.5Very high0 Ų050.1 Ų50.10%027%0.272CS..Hα-helixtrans-67.5-40.8176.91750000110.9V38 D39 A44 A45 R46 V140 V169 H241 Q243 V244V38-V42 HydrophobicContact CG1-CG2 4.17Å; V38-V42 WeakPolarHBondContact O-CB 3.13Å; V38-V42 VanDerWaalsContact O-CG2 3.32Å; V38-V42 WeakPolarHBondContact O-CG2 3.37Å; V38-V42 PolarHBondContact O-N 2.99Å; D39-V42 PolarHBondContact O-N 3.26Å; V42-A44 PolarHBondContact O-N 3.01Å; V42-A45 PolarHBondContact O-N 3.46Å; V42-R46 HydrophobicContact CG1-CG 4.17Å; V42-R46 WeakPolarHBondContact O-CB 2.96Å; V42-R46 VanDerWaalsContact O-CG 3.24Å; V42-R46 WeakPolarHBondContact O-CG 3.43Å; V42-R46 PolarHBondContact O-N 2.85Å; V42-V140 HydrophobicContact CG1-CG1 4.45Å; V42-V169 HydrophobicContact CG2-CG2 3.98Å; V42-H241 WeakPolarHBondContact CG1-CE1 3.32Å; V42-H241 WeakPolarHBondContact CG1-ND1 3.41Å; V42-Q243 HydrophobicContact CG1-CB 3.79Å; V42-Q243 WeakPolarHBondContact CG1-O 3.43Å; V42-V244 HydrophobicContact CG1-CG2 4.37Å; V42-V244 HydrophobicContact CG2-CG2 3.83Å
43S98.5Very high97.3Very high72 Ų7249.8 Ų49.850%0.50327%0.273SS..Hα-helixtrans-59.2-45.4175.3-173.70000111.9D39 K40 R46 L47D39-S43 VanDerWaalsContact O-CB 3.29Å; D39-S43 WeakPolarHBondContact O-CB 3.37Å; D39-S43 PolarHBondContact O-N 2.91Å; K40-S43 PolarHBondContact O-N 2.8Å; S43-R46 PolarHBondContact O-N 3.35Å; S43-L47 PolarHBondContact O-N 3.41Å
44A98.5Very high97Very high12 Ų1254.3 Ų54.310%0.09930%0.296CS..Hα-helixtrans-60.6-47.217400000111.6I3 D4 K40 A41 V42 R46 L47 A48I3-A44 HydrophobicContact CG2-CB 4.3Å; D4-A44 HydrophobicContact CB-CB 4.19Å; K40-A44 PolarHBondContact O-N 3.34Å; A41-A44 PolarHBondContact O-N 3.35Å; V42-A44 PolarHBondContact O-N 3.01Å; A44-R46 VanDerWaalsContact C-N 3.28Å; A44-R46 PolarHBondContact O-N 2.76Å; A44-L47 PolarHBondContact O-N 2.82Å; A44-A48 WeakPolarHBondContact O-CB 3.35Å; A44-A48 PolarHBondContact O-N 3.41Å
45A98.7Very high96.8Very high0 Ų051.7 Ų51.70%029%0.285CS..Hα-helixtrans-59.8-36.7176.200000113A41 V42 G49 V140 T167 V169 G222A41-A45 WeakPolarHBondContact O-CB 3.22Å; A41-A45 PolarHBondContact O-N 3.41Å; V42-A45 PolarHBondContact O-N 3.46Å; A45-G49 PolarHBondContact O-N 3.16Å; A45-V140 HydrophobicContact CB-CB 4.49Å; A45-V140 HydrophobicContact CB-CG1 3.86Å; A45-V140 HydrophobicContact CB-CG2 3.78Å; A45-T167 WeakPolarHBondContact O-CB 3.38Å; A45-T167 WeakPolarHBondContact O-CG2 3.13Å; A45-T167 PolarHBondContact O-OG1 3.3Å; A45-V169 HydrophobicContact CB-CG2 3.96Å; A45-G222 VanDerWaalsContact CA-O 3.24Å; A45-G222 WeakPolarHBondContact CA-O 3Å
46R98.2Very high96.6Very high62 Ų6250.9 Ų50.923%0.23428%0.278CS..Hα-helixtrans-69.1-44.3176-73.5-67.8164.6-166.65.5112V42 S43 A44 A48 G49 K50 V140 Q243 D245V42-R46 HydrophobicContact CG1-CG 4.17Å; V42-R46 WeakPolarHBondContact O-CB 2.96Å; V42-R46 VanDerWaalsContact O-CG 3.24Å; V42-R46 WeakPolarHBondContact O-CG 3.43Å; V42-R46 PolarHBondContact O-N 2.85Å; S43-R46 PolarHBondContact O-N 3.35Å; A44-R46 VanDerWaalsContact C-N 3.28Å; A44-R46 PolarHBondContact O-N 2.76Å; R46-A48 VanDerWaalsContact C-N 3.33Å; R46-G49 PolarHBondContact O-N 3.44Å; R46-K50 PolarHBondContact O-N 2.96Å; R46-V140 VanDerWaalsContact CD-CG2 3.48Å; R46-V140 HydrophobicContact CG-CG2 3.82Å; R46-Q243 HydrophobicContact CG-CB 4.24Å; R46-Q243 PolarHBondContact NE-O 2.95Å; R46-Q243 PolarHBondContact NH2-O 3.02Å; R46-D245 IonicContact CZ-OD1 3.7Å; R46-D245 IonicContact CZ-OD2 2.64Å; R46-D245 IonicContact NH1-OD1 3.71Å; R46-D245 PolarHBondContact NH1-OD1 2.65Å; R46-D245 IonicContact NH1-OD2 2.8Å; R46-D245 PolarHBondContact NH1-OD2 2.82Å; R46-D245 IonicContact NH2-OD1 2.71Å; R46-D245 PolarHBondContact NH2-OD1 3.5Å; R46-D245 IonicContact NH2-OD2 3.64Å; R46-D245 PolarHBondContact NH2-OD2 3.41Å
47L97.9Very high96.3Very high103 Ų10347 Ų4754%0.53927%0.271SS..Hα-helixtrans-62.9-42.9177.9-177.161.8000111.3S43 A44 G49 K50S43-L47 PolarHBondContact O-N 3.41Å; A44-L47 PolarHBondContact O-N 2.82Å; L47-G49 VanDerWaalsContact C-N 3.35Å; L47-K50 HydrophobicContact CD1-CD 4.13Å; L47-K50 WeakPolarHBondContact O-CG 3.49Å
48A97.3Very high95.9Very high9 Ų948 Ų487%0.07428%0.276CS..Hα-helixtrans-69.5-29.1177.200000113.2A44 R46 S53 W55 T167 P221 V223A44-A48 WeakPolarHBondContact O-CB 3.35Å; A44-A48 PolarHBondContact O-N 3.41Å; R46-A48 VanDerWaalsContact C-N 3.33Å; A48-S53 WeakPolarHBondContact O-CB 3.48Å; A48-S53 PolarHBondContact O-OG 3.17Å; A48-W55 WeakPolarHBondContact O-CB 3.46Å; A48-T167 HydrophobicContact CB-CG2 4.06Å; A48-P221 VanDerWaalsContact CB-O 3.28Å; A48-P221 WeakPolarHBondContact CB-O 3.23Å; A48-V223 HydrophobicContact CB-CG2 3.96Å
49G96.5Very high95.6Very high9 Ų953.1 Ų53.19%0.09330%0.3CS..Hα-helixtrans-99.2-1.4-175.900000116.1A45 R46 L47 R56A45-G49 PolarHBondContact O-N 3.16Å; R46-G49 PolarHBondContact O-N 3.44Å; L47-G49 VanDerWaalsContact C-N 3.35Å; G49-R56 WeakPolarHBondContact O-CD 3.49Å; G49-R56 WeakPolarHBondContact O-CG 3.3Å; G49-R56 PolarHBondContact O-NH1 2.88Å
50K95.1Very high95.4Very high109 Ų10953 Ų5347%0.47430%0.303SS..SBendtrans-68.4150.3-177.974.3-175.1177.1-179.50112.1R46 L47 G52 S53 R56R46-K50 PolarHBondContact O-N 2.96Å; L47-K50 HydrophobicContact CD1-CD 4.13Å; L47-K50 WeakPolarHBondContact O-CG 3.49Å; K50-G52 PolarHBondContact O-N 2.94Å; K50-S53 WeakPolarHBondContact O-CB 3.31Å; K50-S53 PolarHBondContact O-N 3.29Å; K50-S53 PolarHBondContact O-OG 2.91Å; K50-R56 VanDerWaalsContact O-CG 3.27Å; K50-R56 WeakPolarHBondContact O-CG 3.42Å
51P92.8Very high95.1Very high108 Ų10851 Ų5170%0.70130%0.301SS*.THydrogen-bonded Turntrans-51.4134.1172.1-26.135.1000112S53P51-S53 VanDerWaalsContact C-N 3.29Å; P51-S53 PolarHBondContact O-N 2.65Å
52G90.5Very high94.8Very high72 Ų7254.1 Ų54.174%0.74231%0.313SS*.THydrogen-bonded Turntrans80.8-3.3-177.500000115.7K50K50-G52 PolarHBondContact O-N 2.94Å
53S94.1Very high94.7Very high13 Ų1355.5 Ų55.59%0.09132%0.318CS..SBendtrans-66.8158.8167.360.40000111.7A48 K50 P51 W55 R56 S57A48-S53 WeakPolarHBondContact O-CB 3.48Å; A48-S53 PolarHBondContact O-OG 3.17Å; K50-S53 WeakPolarHBondContact O-CB 3.31Å; K50-S53 PolarHBondContact O-N 3.29Å; K50-S53 PolarHBondContact O-OG 2.91Å; P51-S53 VanDerWaalsContact C-N 3.29Å; P51-S53 PolarHBondContact O-N 2.65Å; S53-W55 VanDerWaalsContact C-N 3.26Å; S53-W55 PolarHBondContact O-N 3.44Å; S53-R56 PolarHBondContact O-N 2.93Å; S53-R56 VanDerWaalsContact O-N 3.1Å; S53-R56 WeakPolarHBondContact OG-CB 3.23Å; S53-R56 WeakPolarHBondContact OG-CG 3.29Å; S53-R56 PolarHBondContact OG-N 3.45Å; S53-S57 PolarHBondContact O-N 2.86Å; S53-S57 PolarHBondContact O-OG 3.12Å
54L92.2Very high94.5Very high94 Ų9452.2 Ų52.249%0.49230%0.295SS..Hα-helixtrans-52.7-42.9177-176.661.7000112.1S57 L58 P220L54-S57 PolarHBondContact O-N 2.87Å; L54-S57 PolarHBondContact O-OG 2.85Å; L54-L58 VanDerWaalsContact O-CB 3.31Å; L54-L58 WeakPolarHBondContact O-CB 3.48Å; L54-L58 PolarHBondContact O-N 3.11Å; L54-P220 HydrophobicContact CB-CB 4.45Å; L54-P220 HydrophobicContact CB-CG 4.11Å; L54-P220 HydrophobicContact CD2-CB 4.17Å; L54-P220 HydrophobicContact CD2-CG 3.81Å; L54-P220 HydrophobicContact CG-CG 3.9Å
55W95.2Very high94.4Very high1 Ų155.1 Ų55.10%0.00431%0.309CS..Hα-helixtrans-67.1-39.1179.9-171.4-126.7000113A48 S53 L58 R63 L66 L162 G165 N166 F219 P220 V223A48-W55 WeakPolarHBondContact O-CB 3.46Å; S53-W55 VanDerWaalsContact C-N 3.26Å; S53-W55 PolarHBondContact O-N 3.44Å; W55-L58 HydrophobicContact CE3-CD2 3.81Å; W55-L58 HydrophobicContact CZ3-CD2 3.67Å; W55-R63 HydrophobicContact CE3-CG 4.43Å; W55-R63 HydrophobicContact CH2-CB 4.12Å; W55-R63 HydrophobicContact CH2-CG 3.71Å; W55-R63 HydrophobicContact CZ2-CG 4.16Å; W55-R63 HydrophobicContact CZ3-CG 3.87Å; W55-L66 HydrophobicContact CH2-CD1 4.47Å; W55-L66 HydrophobicContact CZ3-CD1 3.75Å; W55-L162 HydrophobicContact CZ2-CB 4.19Å; W55-L162 HydrophobicContact CZ2-CD2 3.92Å; W55-L162 WeakPolarHBondContact CZ2-O 3.47Å; W55-G165 PolarHBondContact NE1-O 2.87Å; W55-N166 PolarHBondContact NE1-O 3.47Å; W55-F219 HydrophobicContact CH2-CD1 4.19Å; W55-F219 HydrophobicContact CH2-CE1 4.02Å; W55-F219 HydrophobicContact CZ3-CD1 4.26Å; W55-F219 HydrophobicContact CZ3-CE1 4.47Å; W55-P220 HydrophobicContact CB-CG 4.13Å; W55-P220 HydrophobicContact CE3-CG 4.23Å; W55-V223 HydrophobicContact CB-CG2 3.74Å; W55-V223 HydrophobicContact CD2-CG1 3.91Å; W55-V223 HydrophobicContact CD2-CG2 3.74Å; W55-V223 HydrophobicContact CE3-CG1 4.36Å; W55-V223 HydrophobicContact CE3-CG2 4.18Å; W55-V223 HydrophobicContact CG-CG1 4.32Å; W55-V223 HydrophobicContact CG-CG2 3.51Å; W55-V223 HydrophobicContact CH2-CG1 4.33Å; W55-V223 HydrophobicContact CZ2-CG1 3.86Å
56R93.5Very high94.2Very high72 Ų7255.2 Ų55.227%0.27231%0.31SS..Hα-helixtrans-77-27.1179.8-69.6-62.7-62.6-96.26.5113.4G49 K50 S53 P137G49-R56 WeakPolarHBondContact O-CD 3.49Å; G49-R56 WeakPolarHBondContact O-CG 3.3Å; G49-R56 PolarHBondContact O-NH1 2.88Å; K50-R56 VanDerWaalsContact O-CG 3.27Å; K50-R56 WeakPolarHBondContact O-CG 3.42Å; S53-R56 PolarHBondContact O-N 2.93Å; S53-R56 VanDerWaalsContact O-N 3.1Å; S53-R56 WeakPolarHBondContact OG-CB 3.23Å; S53-R56 WeakPolarHBondContact OG-CG 3.29Å; S53-R56 PolarHBondContact OG-N 3.45Å; R56-P137 VanDerWaalsContact CZ-CG 3.45Å
57S91.3Very high94.2Very high79 Ų7952.3 Ų52.355%0.55230%0.299SS*.Hα-helixtrans-88.7-12.5174.460.30000113.3S53 L54 E59S53-S57 PolarHBondContact O-N 2.86Å; S53-S57 PolarHBondContact O-OG 3.12Å; L54-S57 PolarHBondContact O-N 2.87Å; L54-S57 PolarHBondContact O-OG 2.85Å; S57-E59 PolarHBondContact O-N 3.25Å
58L90.7Very high94.2Very high26 Ų2650.8 Ų50.814%0.13629%0.289CS..SBendtrans-61.3130.9179.8-170.262.2000110.7L54 W55 R62 R63 L66L54-L58 VanDerWaalsContact O-CB 3.31Å; L54-L58 WeakPolarHBondContact O-CB 3.48Å; L54-L58 PolarHBondContact O-N 3.11Å; W55-L58 HydrophobicContact CE3-CD2 3.81Å; W55-L58 HydrophobicContact CZ3-CD2 3.67Å; L58-R62 HydrophobicContact CD1-CB 3.59Å; L58-R62 HydrophobicContact CD1-CG 4.21Å; L58-R62 HydrophobicContact CD2-CB 4.18Å; L58-R62 HydrophobicContact CG-CB 3.74Å; L58-R63 HydrophobicContact CD2-CG 3.9Å; L58-R63 HydrophobicContact CG-CG 4.29Å; L58-R63 PolarHBondContact O-NH1 2.86Å; L58-L66 HydrophobicContact CD2-CD1 3.8Å
59E92.4Very high94.1Very high109 Ų10952 Ų5251%0.50929%0.291SS..  trans-54.6136.4176.5-63.5179.614600110.3S57 C61 R62 R63S57-E59 PolarHBondContact O-N 3.25Å; E59-C61 PolarHBondContact O-N 2.93Å; E59-C61 VanDerWaalsContact O-N 3.17Å; E59-R62 HydrophobicContact CB-CB 4.35Å; E59-R62 HydrophobicContact CB-CG 3.87Å; E59-R62 WeakPolarHBondContact O-CA 3.5Å; E59-R62 WeakPolarHBondContact O-CB 3.48Å; E59-R62 PolarHBondContact O-N 3.21Å; E59-R62 IonicContact OE2-NE 2.84Å; E59-R63 PolarHBondContact O-N 3.04Å
60P94Very high94.1Very high60 Ų6051.6 Ų51.639%0.3929%0.287SS..Hα-helixtrans-51.6-39.6179.5-30.136.7000114.7R62 R63 G64 A115 D116P60-R62 VanDerWaalsContact C-N 3.29Å; P60-R62 PolarHBondContact O-N 2.96Å; P60-R63 WeakPolarHBondContact O-CB 3.2Å; P60-R63 PolarHBondContact O-N 3.48Å; P60-G64 PolarHBondContact O-N 3.17Å; P60-A115 VanDerWaalsContact CB-O 3.32Å; P60-A115 WeakPolarHBondContact CB-O 3.05Å; P60-A115 VanDerWaalsContact O-CB 3.3Å; P60-A115 WeakPolarHBondContact O-CB 3.46Å; P60-D116 HydrophobicContact CB-CB 3.86Å
61C93.1Very high94.3Very high62 Ų6246.4 Ų46.442%0.41926%0.264SS..Hα-helixtrans-64.9-31176.8610000112.9E59 G64 L65 D116E59-C61 PolarHBondContact O-N 2.93Å; E59-C61 VanDerWaalsContact O-N 3.17Å; C61-G64 PolarHBondContact O-N 3.38Å; C61-L65 PolarHBondContact O-N 2.91Å; C61-D116 HydrophobicContact CB-CB 4.38Å
62R92.3Very high94.5Very high65 Ų6545 Ų4525%0.24525%0.251CS..Hα-helixtrans-73.9-31.8176.8-61-68.9-176.6174.53.9112L58 E59 P60 G64 L65 L66 A217L58-R62 HydrophobicContact CD1-CB 3.59Å; L58-R62 HydrophobicContact CD1-CG 4.21Å; L58-R62 HydrophobicContact CD2-CB 4.18Å; L58-R62 HydrophobicContact CG-CB 3.74Å; E59-R62 HydrophobicContact CB-CB 4.35Å; E59-R62 HydrophobicContact CB-CG 3.87Å; E59-R62 WeakPolarHBondContact O-CA 3.5Å; E59-R62 WeakPolarHBondContact O-CB 3.48Å; E59-R62 PolarHBondContact O-N 3.21Å; E59-R62 IonicContact OE2-NE 2.84Å; P60-R62 VanDerWaalsContact C-N 3.29Å; P60-R62 PolarHBondContact O-N 2.96Å; R62-G64 VanDerWaalsContact C-N 3.3Å; R62-L65 PolarHBondContact O-N 3.21Å; R62-L66 WeakPolarHBondContact O-CG 3.12Å; R62-L66 PolarHBondContact O-N 3.46Å; R62-L66 VanDerWaalsContact O-N 3.11Å; R62-A217 HydrophobicContact CB-CB 4.16Å
63R95.1Very high94.9Very high28 Ų2842.3 Ų42.311%0.10622%0.22CC..Hα-helixtrans-61.4-41.4166.9-64.9-163.9-57.9-82.1-2.4111W55 L58 E59 P60 L66 L67 A115 A163W55-R63 HydrophobicContact CE3-CG 4.43Å; W55-R63 HydrophobicContact CH2-CB 4.12Å; W55-R63 HydrophobicContact CH2-CG 3.71Å; W55-R63 HydrophobicContact CZ2-CG 4.16Å; W55-R63 HydrophobicContact CZ3-CG 3.87Å; L58-R63 HydrophobicContact CD2-CG 3.9Å; L58-R63 HydrophobicContact CG-CG 4.29Å; L58-R63 PolarHBondContact O-NH1 2.86Å; E59-R63 PolarHBondContact O-N 3.04Å; P60-R63 WeakPolarHBondContact O-CB 3.2Å; P60-R63 PolarHBondContact O-N 3.48Å; R63-L66 PolarHBondContact O-N 2.74Å; R63-L67 PolarHBondContact O-N 2.86Å; R63-A115 HydrophobicContact CB-CB 4.25Å; R63-A115 PolarHBondContact NH2-O 3.24Å; R63-A163 PolarHBondContact NE-O 3.34Å; R63-A163 PolarHBondContact NH2-O 2.98Å
64G96.1Very high95.1Very high3 Ų341.9 Ų41.93%0.03122%0.216CC..Hα-helixtrans-59.7-46.7173.200000112.6P60 C61 R62 L66 L67 H68 A112P60-G64 PolarHBondContact O-N 3.17Å; C61-G64 PolarHBondContact O-N 3.38Å; R62-G64 VanDerWaalsContact C-N 3.3Å; G64-L66 VanDerWaalsContact C-N 3.29Å; G64-L66 PolarHBondContact O-N 3.5Å; G64-L67 PolarHBondContact O-N 3.4Å; G64-L67 VanDerWaalsContact O-N 3.15Å; G64-H68 PolarHBondContact O-CD2 3.41Å; G64-H68 PolarHBondContact O-N 2.89Å; G64-A112 WeakPolarHBondContact CA-O 3.22Å; G64-A112 WeakPolarHBondContact O-CB 3.43Å
65L95.2Very high95.4Very high74 Ų7440.9 Ų40.939%0.38721%0.209SC..Hα-helixtrans-57.4-40.9176.8-17962.5000112.7C61 R62 H68 R69 I194 A217C61-L65 PolarHBondContact O-N 2.91Å; R62-L65 PolarHBondContact O-N 3.21Å; L65-H68 PolarHBondContact O-N 3.31Å; L65-R69 WeakPolarHBondContact O-CB 3.42Å; L65-R69 PolarHBondContact O-N 3.26Å; L65-I194 HydrophobicContact CD2-CD1 4.49Å; L65-A217 HydrophobicContact CD2-CB 4.37Å
66L95.4Very high95.5Very high2 Ų247 Ų471%0.0123%0.232CC..Hα-helixtrans-64.5-40.3176.9-77171.7000112.9W55 L58 R62 R63 G64 R69 L70 A217 S218 F219W55-L66 HydrophobicContact CH2-CD1 4.47Å; W55-L66 HydrophobicContact CZ3-CD1 3.75Å; L58-L66 HydrophobicContact CD2-CD1 3.8Å; R62-L66 WeakPolarHBondContact O-CG 3.12Å; R62-L66 PolarHBondContact O-N 3.46Å; R62-L66 VanDerWaalsContact O-N 3.11Å; R63-L66 PolarHBondContact O-N 2.74Å; G64-L66 VanDerWaalsContact C-N 3.29Å; G64-L66 PolarHBondContact O-N 3.5Å; L66-R69 PolarHBondContact O-N 2.79Å; L66-L70 PolarHBondContact O-N 2.91Å; L66-A217 HydrophobicContact CD1-CB 4.36Å; L66-A217 HydrophobicContact CD2-CB 4.27Å; L66-A217 VanDerWaalsContact CD2-O 3.29Å; L66-A217 WeakPolarHBondContact CD2-O 3.22Å; L66-A217 HydrophobicContact CG-CB 4.04Å; L66-S218 WeakPolarHBondContact CD1-O 3.45Å; L66-F219 HydrophobicContact CB-CD2 4.27Å; L66-F219 HydrophobicContact CB-CE1 4.18Å; L66-F219 HydrophobicContact CB-CE2 3.72Å; L66-F219 HydrophobicContact CB-CZ 3.68Å; L66-F219 HydrophobicContact CD1-CD1 4.46Å; L66-F219 HydrophobicContact CD1-CG 4.46Å; L66-F219 HydrophobicContact CD2-CD2 3.97Å; L66-F219 HydrophobicContact CD2-CE2 4.15Å; L66-F219 HydrophobicContact CG-CE2 4.45Å
67L97.4Very high95.8Very high0 Ų044.9 Ų44.90%023%0.226CC..Hα-helixtrans-67-42.1174.9-75.7171.5000112.3R63 G64 R69 L70 A71 L108 A112 L162 A163R63-L67 PolarHBondContact O-N 2.86Å; G64-L67 PolarHBondContact O-N 3.4Å; G64-L67 VanDerWaalsContact O-N 3.15Å; L67-R69 VanDerWaalsContact C-N 3.3Å; L67-R69 PolarHBondContact O-N 2.93Å; L67-L70 PolarHBondContact O-N 3.36Å; L67-A71 PolarHBondContact O-N 3.33Å; L67-L108 HydrophobicContact CD2-CD2 4.13Å; L67-A112 HydrophobicContact CB-CB 3.61Å; L67-A112 HydrophobicContact CD1-CB 4.5Å; L67-L162 HydrophobicContact CD1-CB 4.46Å; L67-L162 HydrophobicContact CD2-CB 4.03Å; L67-L162 HydrophobicContact CD2-CD1 4.02Å; L67-L162 HydrophobicContact CG-CB 4.48Å; L67-A163 HydrophobicContact CD1-CB 3.85Å
68H97.4Very high96.1Very high72 Ų7247.9 Ų47.933%0.33323%0.225SC..Hα-helixtrans-58-45.7172.5-83.3-56.9000111.3G64 L65 L70 A71 D72 A112G64-H68 PolarHBondContact O-CD2 3.41Å; G64-H68 PolarHBondContact O-N 2.89Å; L65-H68 PolarHBondContact O-N 3.31Å; H68-L70 PolarHBondContact O-N 3.27Å; H68-A71 WeakPolarHBondContact O-CA 3.44Å; H68-A71 WeakPolarHBondContact O-CB 3.39Å; H68-A71 PolarHBondContact O-N 2.83Å; H68-A71 VanDerWaalsContact O-N 3.09Å; H68-D72 VanDerWaalsContact O-CG 3.32Å; H68-D72 PolarHBondContact O-N 3.45Å; H68-A112 VanDerWaalsContact CD2-CB 3.44Å; H68-A112 WeakPolarHBondContact CD2-CB 3.33Å; H68-A112 WeakPolarHBondContact NE2-CB 3.12Å
69R95.3Very high96.5Very high34 Ų3450.6 Ų50.613%0.12824%0.243CC..Hα-helixtrans-65-38.7-179.9-174.6156.2175.4-117.2-37.5113.2L65 L66 L67 A71 D72 L73 E189 A190L65-R69 WeakPolarHBondContact O-CB 3.42Å; L65-R69 PolarHBondContact O-N 3.26Å; L66-R69 PolarHBondContact O-N 2.79Å; L67-R69 VanDerWaalsContact C-N 3.3Å; L67-R69 PolarHBondContact O-N 2.93Å; R69-A71 VanDerWaalsContact C-N 3.29Å; R69-A71 PolarHBondContact O-N 2.85Å; R69-D72 PolarHBondContact O-N 3.35Å; R69-L73 WeakPolarHBondContact O-CG 3.3Å; R69-L73 PolarHBondContact O-N 3.2Å; R69-E189 PolarHBondContact NH2-O 3.18Å; R69-A190 HydrophobicContact CG-CB 4.47Å; R69-A190 PolarHBondContact NH1-O 3.45Å; R69-A190 VanDerWaalsContact NH2-CA 3.31Å; R69-A190 PolarHBondContact NH2-O 3.46Å
70L97.7Very high96.7Very high0 Ų051.7 Ų51.70%024%0.243CC..Hα-helixtrans-60.1-43.1171.7179.259.8000111.1L66 L67 H68 D72 L73 M74 L108 I158 V183 L186 I187 F219L66-L70 PolarHBondContact O-N 2.91Å; L67-L70 PolarHBondContact O-N 3.36Å; H68-L70 PolarHBondContact O-N 3.27Å; L70-D72 VanDerWaalsContact C-N 3.34Å; L70-D72 PolarHBondContact O-N 3.13Å; L70-L73 PolarHBondContact O-N 2.99Å; L70-M74 HydrophobicContact CG-SD 4.35Å; L70-M74 WeakPolarHBondContact O-CG 3.43Å; L70-M74 PolarHBondContact O-N 3.29Å; L70-L108 HydrophobicContact CD2-CD1 4.06Å; L70-L108 HydrophobicContact CD2-CD2 4.47Å; L70-L108 HydrophobicContact CG-CD1 4.03Å; L70-I158 HydrophobicContact CD2-CD1 4.24Å; L70-V183 HydrophobicContact CD1-CG1 4.4Å; L70-L186 HydrophobicContact CD1-CB 3.88Å; L70-I187 HydrophobicContact CD1-CG1 3.77Å; L70-I187 HydrophobicContact CD2-CD1 4.36Å; L70-I187 HydrophobicContact CD2-CG1 3.93Å; L70-I187 HydrophobicContact CG-CG1 4.49Å; L70-F219 HydrophobicContact CB-CE2 4.47Å
71A98.4Very high97Very high0 Ų048.9 Ų48.90%023%0.225CC..Hα-helixtrans-61.9-40.6176.800000112.2L67 H68 R69 M74 E75 I105 L108 R109L67-A71 PolarHBondContact O-N 3.33Å; H68-A71 WeakPolarHBondContact O-CA 3.44Å; H68-A71 WeakPolarHBondContact O-CB 3.39Å; H68-A71 PolarHBondContact O-N 2.83Å; H68-A71 VanDerWaalsContact O-N 3.09Å; R69-A71 VanDerWaalsContact C-N 3.29Å; R69-A71 PolarHBondContact O-N 2.85Å; A71-M74 PolarHBondContact O-N 3.45Å; A71-E75 WeakPolarHBondContact O-CB 3.45Å; A71-E75 PolarHBondContact O-N 2.7Å; A71-I105 HydrophobicContact CB-CG2 4.26Å; A71-L108 HydrophobicContact CB-CB 3.99Å; A71-L108 HydrophobicContact CB-CD1 4.41Å; A71-R109 HydrophobicContact CB-CG 3.72Å
72D98.1Very high97.2Very high80 Ų8046 Ų4643%0.42821%0.205SC..Hα-helixtrans-67.6-36.6177.3-62-20.7000112.1H68 R69 L70 E75 R76 R109H68-D72 VanDerWaalsContact O-CG 3.32Å; H68-D72 PolarHBondContact O-N 3.45Å; R69-D72 PolarHBondContact O-N 3.35Å; L70-D72 VanDerWaalsContact C-N 3.34Å; L70-D72 PolarHBondContact O-N 3.13Å; D72-E75 PolarHBondContact O-N 3.37Å; D72-R76 WeakPolarHBondContact O-CB 3.35Å; D72-R76 PolarHBondContact O-N 3.31Å; D72-R109 IonicContact OD1-CZ 2.88Å; D72-R109 IonicContact OD1-NE 3.26Å; D72-R109 IonicContact OD1-NH2 3.63Å; D72-R109 PolarHBondContact OD1-NH2 2.96Å
73L97.8Very high97.5Very high15 Ų1544.6 Ų44.68%0.07921%0.206CC..Hα-helixtrans-67.6-38.2173.1-70.2174.2000112.1R69 L70 E75 R76 D77 L186 E189 A190R69-L73 WeakPolarHBondContact O-CG 3.3Å; R69-L73 PolarHBondContact O-N 3.2Å; L70-L73 PolarHBondContact O-N 2.99Å; L73-E75 VanDerWaalsContact C-N 3.34Å; L73-R76 WeakPolarHBondContact O-CB 3.49Å; L73-R76 PolarHBondContact O-N 2.96Å; L73-D77 PolarHBondContact O-N 3.4Å; L73-L186 HydrophobicContact CB-CB 4.3Å; L73-L186 HydrophobicContact CB-CD1 4.41Å; L73-L186 HydrophobicContact CB-CD2 4.35Å; L73-L186 HydrophobicContact CD1-CB 4.5Å; L73-L186 VanDerWaalsContact CD1-O 3.31Å; L73-L186 WeakPolarHBondContact CD1-O 3.23Å; L73-E189 HydrophobicContact CD1-CB 4.21Å; L73-E189 WeakPolarHBondContact CD2-OE1 3.34Å; L73-A190 HydrophobicContact CD1-CB 3.88Å
74M98.5Very high97.7Very high3 Ų344.4 Ų44.42%0.01521%0.206CC..Hα-helixtrans-65.6-38.4172.8-73.2178.657.300111.9L70 A71 D77 R78 L81 L101 A104 I105 L108 L151 V183 L186L70-M74 HydrophobicContact CG-SD 4.35Å; L70-M74 WeakPolarHBondContact O-CG 3.43Å; L70-M74 PolarHBondContact O-N 3.29Å; A71-M74 PolarHBondContact O-N 3.45Å; M74-D77 CarbonylContact O-C 3.6Å; M74-D77 PolarHBondContact O-N 2.87Å; M74-R78 WeakPolarHBondContact O-CA 3.49Å; M74-R78 PolarHBondContact O-N 3.04Å; M74-R78 VanDerWaalsContact O-N 3.09Å; M74-L81 HydrophobicContact CB-CD1 3.92Å; M74-L81 HydrophobicContact CG-CD1 3.95Å; M74-L101 HydrophobicContact CE-CD1 4.08Å; M74-A104 HydrophobicContact CE-CB 3.99Å; M74-I105 HydrophobicContact CB-CD1 4.41Å; M74-I105 HydrophobicContact CB-CG1 4.02Å; M74-I105 HydrophobicContact CE-CG1 4.37Å; M74-L108 HydrophobicContact CE-CD1 4.33Å; M74-L108 HydrophobicContact SD-CD1 3.35Å; M74-L108 WeakPolarHBondContact SD-CD1 3.26Å; M74-L151 HydrophobicContact CE-CD1 3.79Å; M74-L151 HydrophobicContact CE-CD2 4.22Å; M74-L151 HydrophobicContact CE-CG 4.11Å; M74-V183 HydrophobicContact SD-CG2 4.36Å; M74-L186 HydrophobicContact CG-CD1 3.82Å
75E98.4Very high97.8Very high73 Ų7344.3 Ų44.334%0.34121%0.205SC..Hα-helixtrans-66.9-40175.3-168.9168.6-116.800111.8A71 D72 L73 D77 R78 I105 R109A71-E75 WeakPolarHBondContact O-CB 3.45Å; A71-E75 PolarHBondContact O-N 2.7Å; D72-E75 PolarHBondContact O-N 3.37Å; L73-E75 VanDerWaalsContact C-N 3.34Å; E75-D77 VanDerWaalsContact C-N 3.33Å; E75-D77 PolarHBondContact O-N 3.39Å; E75-R78 VanDerWaalsContact O-CB 3.25Å; E75-R78 WeakPolarHBondContact O-CB 3.42Å; E75-R78 WeakPolarHBondContact O-CD 3.46Å; E75-R78 WeakPolarHBondContact O-CG 3.36Å; E75-R78 PolarHBondContact O-N 3.03Å; E75-I105 HydrophobicContact CB-CD1 3.92Å; E75-I105 HydrophobicContact CG-CD1 4.41Å; E75-R109 VanDerWaalsContact CD-NH2 3.33Å; E75-R109 IonicContact OE1-CZ 2.65Å; E75-R109 IonicContact OE1-NH1 2.64Å; E75-R109 PolarHBondContact OE1-NH1 2.92Å; E75-R109 IonicContact OE1-NH2 3.97Å; E75-R109 IonicContact OE2-CZ 2.71Å; E75-R109 IonicContact OE2-NH1 3.76Å; E75-R109 IonicContact OE2-NH2 3.91Å; E75-R109 PolarHBondContact OE2-NH2 3.5Å
76R98.2Very high98Very high130 Ų13040.8 Ų40.849%0.49119%0.187SC..Hα-helixtrans-56.9-47.2171.5-176.9-161.971.7-175.63.3111.1D72 L73 R78 E189D72-R76 WeakPolarHBondContact O-CB 3.35Å; D72-R76 PolarHBondContact O-N 3.31Å; L73-R76 WeakPolarHBondContact O-CB 3.49Å; L73-R76 PolarHBondContact O-N 2.96Å; R76-R78 VanDerWaalsContact C-N 3.26Å; R76-R78 PolarHBondContact O-N 3.22Å; R76-E189 IonicContact CZ-OE1 3.92Å; R76-E189 IonicContact CZ-OE2 2.59Å; R76-E189 IonicContact NH1-OE1 3.15Å; R76-E189 PolarHBondContact NH1-OE1 2.91Å; R76-E189 IonicContact NH1-OE2 3.81Å; R76-E189 PolarHBondContact NH1-OE2 3.22Å; R76-E189 IonicContact NH2-OE1 3.77Å; R76-E189 IonicContact NH2-OE2 2.78Å; R76-E189 PolarHBondContact NH2-OE2 2.78Å
77D98.4Very high98.1Very high28 Ų2843.2 Ų43.215%0.1520%0.199CC..THydrogen-bonded Turntrans-88.114.8-176.4-75.921.7000113.5L73 M74 E75 V79 Y80 L81 H182 L186L73-D77 PolarHBondContact O-N 3.4Å; M74-D77 CarbonylContact O-C 3.6Å; M74-D77 PolarHBondContact O-N 2.87Å; E75-D77 VanDerWaalsContact C-N 3.33Å; E75-D77 PolarHBondContact O-N 3.39Å; D77-V79 VanDerWaalsContact C-N 3.29Å; D77-V79 PolarHBondContact O-N 3.25Å; D77-V79 VanDerWaalsContact O-N 3.1Å; D77-Y80 WeakPolarHBondContact O-CB 3.47Å; D77-Y80 PolarHBondContact O-N 3.1Å; D77-L81 HydrophobicContact CB-CD1 4.28Å; D77-L81 HydrophobicContact CB-CG 4.41Å; D77-L81 PolarHBondContact O-N 3.29Å; D77-H182 IonicContact OD2-CD2 2.97Å; D77-H182 IonicContact OD2-CE1 2.66Å; D77-H182 IonicContact OD2-NE2 3.33Å; D77-H182 PolarHBondContact OD2-NE2 3.05Å; D77-L186 WeakPolarHBondContact OD2-CD2 3.4Å
78R98.4Very high98.1Very high142 Ų14243.2 Ų43.254%0.53620%0.199SC..Hα-helixtrans-52.1-41.4-169.763.7-176.2-169.7170.52.1115.3M74 E75 R76 A82 L97 L101M74-R78 WeakPolarHBondContact O-CA 3.49Å; M74-R78 PolarHBondContact O-N 3.04Å; M74-R78 VanDerWaalsContact O-N 3.09Å; E75-R78 VanDerWaalsContact O-CB 3.25Å; E75-R78 WeakPolarHBondContact O-CB 3.42Å; E75-R78 WeakPolarHBondContact O-CD 3.46Å; E75-R78 WeakPolarHBondContact O-CG 3.36Å; E75-R78 PolarHBondContact O-N 3.03Å; R76-R78 VanDerWaalsContact C-N 3.26Å; R76-R78 PolarHBondContact O-N 3.22Å; R78-A82 VanDerWaalsContact O-CB 3.23Å; R78-A82 WeakPolarHBondContact O-CB 3.16Å; R78-A82 PolarHBondContact O-N 2.88Å; R78-L97 HydrophobicContact CB-CD1 4.35Å; R78-L101 HydrophobicContact CB-CD2 3.25Å
79V98.2Very high98.2Very high82 Ų8239.8 Ų39.850%0.49718%0.184SC..Hα-helixtrans-68.1-41.9-179.3176.70000110.1D77 S83D77-V79 VanDerWaalsContact C-N 3.29Å; D77-V79 PolarHBondContact O-N 3.25Å; D77-V79 VanDerWaalsContact O-N 3.1Å; V79-S83 VanDerWaalsContact O-CB 3.31Å; V79-S83 WeakPolarHBondContact O-CB 3.3Å; V79-S83 PolarHBondContact O-N 3.25Å; V79-S83 PolarHBondContact O-OG 3.46Å
80Y98.5Very high98.3Very high133 Ų13338.1 Ų38.152%0.52218%0.177SC..Hα-helixtrans-68.4-49.5179.6-175.2-97.1000111.1D77 A82 S83 L84 H182D77-Y80 WeakPolarHBondContact O-CB 3.47Å; D77-Y80 PolarHBondContact O-N 3.1Å; Y80-A82 PolarHBondContact O-N 2.99Å; Y80-S83 PolarHBondContact O-N 2.77Å; Y80-L84 HydrophobicContact CE1-CD2 4.1Å; Y80-L84 WeakPolarHBondContact O-CB 3.32Å; Y80-L84 PolarHBondContact O-N 2.85Å; Y80-H182 AromaticContact CD1-CD2 3.76Å; Y80-H182 AromaticContact CD1-CE1 3.67Å; Y80-H182 AromaticContact CD1-CG 3.99Å; Y80-H182 AromaticContact CD1-ND1 3.96Å; Y80-H182 AromaticContact CD1-NE2 3.54Å; Y80-H182 HydrophobicContact CE1-CB 4.49Å; Y80-H182 AromaticContact CE1-CD2 3.95Å; Y80-H182 AromaticContact CE1-CE1 3.5Å; Y80-H182 VanDerWaalsContact CE1-CE1 3.5Å; Y80-H182 WeakPolarHBondContact CE1-CE1 3.22Å; Y80-H182 AromaticContact CE1-CG 3.69Å; Y80-H182 AromaticContact CE1-ND1 3.41Å; Y80-H182 WeakPolarHBondContact CE1-ND1 3.42Å; Y80-H182 AromaticContact CE1-NE2 3.82Å
81L98.7Very high98.3Very high0 Ų038.1 Ų38.10%018%0.177CC..Hα-helixtrans-58.5-46.9177.4-82169.5000112.2M74 D77 S83 L84 E85 L101 L151 T179 H182 V183 L186M74-L81 HydrophobicContact CB-CD1 3.92Å; M74-L81 HydrophobicContact CG-CD1 3.95Å; D77-L81 HydrophobicContact CB-CD1 4.28Å; D77-L81 HydrophobicContact CB-CG 4.41Å; D77-L81 PolarHBondContact O-N 3.29Å; L81-S83 VanDerWaalsContact C-N 3.34Å; L81-S83 PolarHBondContact O-N 2.78Å; L81-L84 PolarHBondContact O-N 2.85Å; L81-E85 WeakPolarHBondContact O-CB 3.25Å; L81-E85 PolarHBondContact O-N 3.11Å; L81-L101 HydrophobicContact CB-CD1 4.09Å; L81-L101 HydrophobicContact CD1-CD1 3.85Å; L81-L151 HydrophobicContact CB-CD2 4.32Å; L81-L151 HydrophobicContact CD2-CD1 4.36Å; L81-L151 HydrophobicContact CD2-CD2 4.35Å; L81-T179 HydrophobicContact CD2-CG2 4.46Å; L81-H182 HydrophobicContact CD2-CB 4.22Å; L81-V183 HydrophobicContact CD2-CG2 4.3Å; L81-L186 HydrophobicContact CD1-CD1 4.21Å
82A98.6Very high98.3Very high1 Ų138.2 Ų38.21%0.00818%0.178CC..Hα-helixtrans-66.1-36.7178.600000112.5R78 Y80 T86 Y93 L97R78-A82 VanDerWaalsContact O-CB 3.23Å; R78-A82 WeakPolarHBondContact O-CB 3.16Å; R78-A82 PolarHBondContact O-N 2.88Å; Y80-A82 PolarHBondContact O-N 2.99Å; A82-T86 WeakPolarHBondContact O-CB 3.37Å; A82-T86 PolarHBondContact O-N 3.41Å; A82-T86 PolarHBondContact O-OG1 3.31Å; A82-Y93 HydrophobicContact CB-CD2 4.36Å; A82-Y93 HydrophobicContact CB-CE2 3.75Å; A82-L97 HydrophobicContact CB-CB 3.83Å; A82-L97 HydrophobicContact CB-CD1 3.89Å; A82-L97 HydrophobicContact CB-CG 4.47Å
83S98.6Very high98.3Very high37 Ų3737 Ų3726%0.25917%0.168SC..Hα-helixtrans-67.1-41.9176.5-57.40000111.1V79 Y80 L81 T86 L87 Y93 F341V79-S83 VanDerWaalsContact O-CB 3.31Å; V79-S83 WeakPolarHBondContact O-CB 3.3Å; V79-S83 PolarHBondContact O-N 3.25Å; V79-S83 PolarHBondContact O-OG 3.46Å; Y80-S83 PolarHBondContact O-N 2.77Å; L81-S83 VanDerWaalsContact C-N 3.34Å; L81-S83 PolarHBondContact O-N 2.78Å; S83-T86 PolarHBondContact O-N 3.08Å; S83-L87 VanDerWaalsContact O-CB 3.3Å; S83-L87 WeakPolarHBondContact O-CB 3.19Å; S83-L87 PolarHBondContact O-N 2.79Å; S83-Y93 WeakPolarHBondContact OG-CE2 3.33Å; S83-F341 WeakPolarHBondContact O-CZ 3.45Å
84L98.4Very high98.3Very high23 Ų2340.1 Ų40.112%0.1219%0.187CC..Hα-helixtrans-65.7-43.9177.5-167.161.3000111.3Y80 L81 T86 L87 D88 L178 T179 H182Y80-L84 HydrophobicContact CE1-CD2 4.1Å; Y80-L84 WeakPolarHBondContact O-CB 3.32Å; Y80-L84 PolarHBondContact O-N 2.85Å; L81-L84 PolarHBondContact O-N 2.85Å; L84-T86 PolarHBondContact O-N 2.86Å; L84-L87 PolarHBondContact O-N 3.25Å; L84-D88 VanDerWaalsContact O-CB 3.31Å; L84-D88 WeakPolarHBondContact O-CB 3.44Å; L84-D88 PolarHBondContact O-N 3.03Å; L84-L178 HydrophobicContact CD1-CB 3.72Å; L84-L178 HydrophobicContact CD1-CD1 3.64Å; L84-L178 HydrophobicContact CD1-CG 4.31Å; L84-L178 HydrophobicContact CD2-CB 3.85Å; L84-L178 HydrophobicContact CG-CB 3.66Å; L84-L178 HydrophobicContact CG-CD1 4.43Å; L84-T179 HydrophobicContact CB-CG2 3.9Å; L84-T179 HydrophobicContact CD2-CG2 4.08Å; L84-T179 HydrophobicContact CG-CG2 3.94Å; L84-H182 HydrophobicContact CD2-CB 4.06Å
85E98.5Very high98.2Very high2 Ų241.4 Ų41.41%0.00919%0.193CC..Hα-helixtrans-59.4-46.4175.9-16582.6149.300110.9L81 N89 P150 L151 T179L81-E85 WeakPolarHBondContact O-CB 3.25Å; L81-E85 PolarHBondContact O-N 3.11Å; E85-N89 WeakPolarHBondContact O-CB 3.46Å; E85-N89 PolarHBondContact O-N 2.66Å; E85-P150 WeakPolarHBondContact OE1-CD 3.35Å; E85-L151 VanDerWaalsContact OE1-CB 3.24Å; E85-L151 WeakPolarHBondContact OE1-CB 3.46Å; E85-L151 PolarHBondContact OE1-N 2.96Å; E85-T179 HydrophobicContact CB-CG2 3.9Å; E85-T179 VanDerWaalsContact OE2-CB 3.28Å; E85-T179 WeakPolarHBondContact OE2-CB 3.29Å; E85-T179 WeakPolarHBondContact OE2-CG2 3.39Å; E85-T179 PolarHBondContact OE2-OG1 2.64Å
86T98.6Very high98.2Very high0 Ų038 Ų380%018%0.177CC..Hα-helixtrans-66.4-39.4177.9-78.60000113.2A82 S83 L84 G90 K91 Y93 S96 P340 F341A82-T86 WeakPolarHBondContact O-CB 3.37Å; A82-T86 PolarHBondContact O-N 3.41Å; A82-T86 PolarHBondContact O-OG1 3.31Å; S83-T86 PolarHBondContact O-N 3.08Å; L84-T86 PolarHBondContact O-N 2.86Å; T86-G90 VanDerWaalsContact O-CA 3.29Å; T86-G90 WeakPolarHBondContact O-CA 3.2Å; T86-G90 PolarHBondContact O-N 3.04Å; T86-K91 WeakPolarHBondContact CB-O 3.39Å; T86-K91 VanDerWaalsContact CG2-O 3.23Å; T86-K91 WeakPolarHBondContact CG2-O 3.25Å; T86-K91 PolarHBondContact OG1-O 3.49Å; T86-Y93 VanDerWaalsContact OG1-CA 3.26Å; T86-Y93 WeakPolarHBondContact OG1-CA 3.39Å; T86-Y93 PolarHBondContact OG1-N 3.01Å; T86-S96 WeakPolarHBondContact OG1-CB 3.33Å; T86-S96 PolarHBondContact OG1-OG 3.31Å; T86-P340 HydrophobicContact CG2-CB 3.49Å; T86-P340 VanDerWaalsContact CG2-CB 3.49Å; T86-F341 HydrophobicContact CG2-CD1 4.18Å; T86-F341 HydrophobicContact CG2-CD2 4.02Å; T86-F341 HydrophobicContact CG2-CE1 3.89Å; T86-F341 HydrophobicContact CG2-CE2 3.71Å; T86-F341 HydrophobicContact CG2-CG 4.25Å; T86-F341 HydrophobicContact CG2-CZ 3.65Å
87L98.5Very high98.2Very high52 Ų5234.4 Ų34.427%0.27217%0.167SC..Hα-helixtrans-63.7-43.4178.1-179.665.4000111.9N20 I27 S83 L84 F341N20-L87 WeakPolarHBondContact ND2-CD1 3.19Å; I27-L87 HydrophobicContact CD1-CG 3.93Å; I27-L87 HydrophobicContact CG1-CD1 4.47Å; I27-L87 HydrophobicContact CG1-CD2 4.5Å; I27-L87 HydrophobicContact CG1-CG 4.19Å; I27-L87 HydrophobicContact CG2-CD2 3.85Å; I27-L87 HydrophobicContact CG2-CG 4.42Å; S83-L87 VanDerWaalsContact O-CB 3.3Å; S83-L87 WeakPolarHBondContact O-CB 3.19Å; S83-L87 PolarHBondContact O-N 2.79Å; L84-L87 PolarHBondContact O-N 3.25Å; L87-F341 HydrophobicContact CB-CE2 4.44Å; L87-F341 HydrophobicContact CB-CZ 4.26Å
88D98.1Very high98.1Very high0 Ų036 Ų360%019%0.185CC..Hα-helixtrans-80.6-37-174.8-145.624000111.6T18 L84 T176 L178T18-D88 PolarHBondContact OG1-OD1 3.47Å; L84-D88 VanDerWaalsContact O-CB 3.31Å; L84-D88 WeakPolarHBondContact O-CB 3.44Å; L84-D88 PolarHBondContact O-N 3.03Å; D88-T176 HydrophobicContact CB-CG2 4.37Å; D88-T176 WeakPolarHBondContact OD2-CA 3.49Å; D88-L178 HydrophobicContact CB-CD1 4.14Å; D88-L178 HydrophobicContact CB-CG 4.45Å; D88-L178 WeakPolarHBondContact OD1-CD1 3.49Å; D88-L178 VanDerWaalsContact OD2-CB 3.25Å; D88-L178 WeakPolarHBondContact OD2-CB 3.28Å; D88-L178 WeakPolarHBondContact OD2-CG 3.36Å; D88-L178 PolarHBondContact OD2-N 3.24Å
89N97.7Very high98Very high0 Ų032.1 Ų32.10%017%0.174CC..Hα-helixtrans-99.8-28.1-174.8178.2-94.3000114.9P21 E85 K91 W147 T176P21-N89 WeakPolarHBondContact CG-O 3.45Å; E85-N89 WeakPolarHBondContact O-CB 3.46Å; E85-N89 PolarHBondContact O-N 2.66Å; N89-K91 VanDerWaalsContact CG-CE 3.47Å; N89-K91 WeakPolarHBondContact OD1-CB 3.46Å; N89-K91 WeakPolarHBondContact OD1-CE 3.42Å; N89-K91 PolarHBondContact OD1-N 3.37Å; N89-W147 PolarHBondContact ND2-O 3Å; N89-T176 HydrophobicContact CB-CG2 4.09Å
90G98.1Very high98Very high0 Ų028.2 Ų28.20%015%0.15CC..  trans82.34.9-177.400000115.7T86 Q304 P340 G348 P349T86-G90 VanDerWaalsContact O-CA 3.29Å; T86-G90 WeakPolarHBondContact O-CA 3.2Å; T86-G90 PolarHBondContact O-N 3.04Å; G90-Q304 PolarHBondContact O-NE2 3.14Å; G90-Q304 VanDerWaalsContact O-NE2 3.11Å; G90-P340 WeakPolarHBondContact O-CG 3.4Å; G90-G348 WeakPolarHBondContact O-CA 3.41Å; G90-P349 WeakPolarHBondContact O-CD 3.25Å
91K98.1Very high98Very high0 Ų022.1 Ų22.10%013%0.127CC..  trans-72.7147.6171.873.4-175.464.9-172.50111.7T86 N89 Y93 S96 D100 N148 N303 P340T86-K91 WeakPolarHBondContact CB-O 3.39Å; T86-K91 VanDerWaalsContact CG2-O 3.23Å; T86-K91 WeakPolarHBondContact CG2-O 3.25Å; T86-K91 PolarHBondContact OG1-O 3.49Å; N89-K91 VanDerWaalsContact CG-CE 3.47Å; N89-K91 WeakPolarHBondContact OD1-CB 3.46Å; N89-K91 WeakPolarHBondContact OD1-CE 3.42Å; N89-K91 PolarHBondContact OD1-N 3.37Å; K91-Y93 PolarHBondContact O-N 3.43Å; K91-S96 WeakPolarHBondContact CD-OG 3.44Å; K91-S96 WeakPolarHBondContact CG-OG 3.48Å; K91-D100 IonicContact NZ-OD1 3.97Å; K91-D100 IonicContact NZ-OD2 3.05Å; K91-D100 PolarHBondContact NZ-OD2 3.03Å; K91-N148 WeakPolarHBondContact CE-O 3.24Å; K91-N148 PolarHBondContact NZ-O 3.22Å; K91-N303 WeakPolarHBondContact CB-OD1 3.3Å; K91-N303 WeakPolarHBondContact CE-OD1 3.48Å; K91-P340 WeakPolarHBondContact O-CB 3.35Å
92P98.2Very high97.9Very high2 Ų225 Ų251%0.01314%0.14CC..  trans-48.8135.5175.4-29.135000113V94 H95 S96 P340 T345P92-V94 HydrophobicContact CB-CG1 4.3Å; P92-V94 PolarHBondContact O-N 3.45Å; P92-V94 VanDerWaalsContact O-N 3.17Å; P92-H95 WeakPolarHBondContact O-CA 3.47Å; P92-H95 WeakPolarHBondContact O-CB 3.22Å; P92-H95 PolarHBondContact O-N 3.13Å; P92-S96 PolarHBondContact O-N 3.38Å; P92-P340 CarbonylContact C-O 3.56Å; P92-P340 WeakPolarHBondContact CA-O 3.38Å; P92-T345 HydrophobicContact CG-CG2 4.36Å
93Y98.5Very high97.9Very high55 Ų5526.7 Ų26.722%0.21615%0.149CC..Hα-helixtrans-53-39.5-177176.6-101.5000112.9A82 S83 T86 K91 H95 S96 L97 P340 F341A82-Y93 HydrophobicContact CB-CD2 4.36Å; A82-Y93 HydrophobicContact CB-CE2 3.75Å; S83-Y93 WeakPolarHBondContact OG-CE2 3.33Å; T86-Y93 VanDerWaalsContact OG1-CA 3.26Å; T86-Y93 WeakPolarHBondContact OG1-CA 3.39Å; T86-Y93 PolarHBondContact OG1-N 3.01Å; K91-Y93 PolarHBondContact O-N 3.43Å; Y93-H95 PolarHBondContact O-N 3.01Å; Y93-S96 PolarHBondContact O-N 3.32Å; Y93-L97 HydrophobicContact CE1-CB 4.33Å; Y93-L97 HydrophobicContact CE1-CD2 3.8Å; Y93-L97 WeakPolarHBondContact O-CB 3.32Å; Y93-L97 PolarHBondContact O-N 3.11Å; Y93-P340 PolarHBondContact N-O 3.18Å; Y93-F341 HydrophobicContact CD2-CD1 4.13Å; Y93-F341 HydrophobicContact CD2-CE1 4Å; Y93-F341 HydrophobicContact CG-CD1 4.35Å
94V97.1Very high97.9Very high80 Ų8024.9 Ų24.949%0.48514%0.136SC..Hα-helixtrans-61.3-33.7177.770.30000112.3P92 A98P92-V94 HydrophobicContact CB-CG1 4.3Å; P92-V94 PolarHBondContact O-N 3.45Å; P92-V94 VanDerWaalsContact O-N 3.17Å; V94-A98 WeakPolarHBondContact O-CB 3.39Å; V94-A98 PolarHBondContact O-N 3.01Å
95H97.2Very high97.9Very high29 Ų2924 Ų2413%0.13413%0.131CC..Hα-helixtrans-71.2-46.1175.3-59.1163.9000110.8P92 Y93 L97 I99 D100 F302P92-H95 WeakPolarHBondContact O-CA 3.47Å; P92-H95 WeakPolarHBondContact O-CB 3.22Å; P92-H95 PolarHBondContact O-N 3.13Å; Y93-H95 PolarHBondContact O-N 3.01Å; H95-L97 VanDerWaalsContact C-N 3.3Å; H95-L97 PolarHBondContact O-N 2.88Å; H95-I99 HydrophobicContact CB-CD1 4.42Å; H95-I99 WeakPolarHBondContact O-CA 3.38Å; H95-I99 VanDerWaalsContact O-CB 3.3Å; H95-I99 WeakPolarHBondContact O-CB 3.45Å; H95-I99 PolarHBondContact O-N 3.21Å; H95-D100 PolarHBondContact O-N 3.35Å; H95-D100 VanDerWaalsContact O-N 3.13Å; H95-F302 HydrophobicContact CB-CE2 4.01Å; H95-F302 AromaticContact CD2-CE2 3.95Å; H95-F302 AromaticContact CE1-CD2 3.94Å; H95-F302 AromaticContact CG-CE2 3.64Å; H95-F302 AromaticContact ND1-CD2 3.96Å; H95-F302 AromaticContact ND1-CE2 3.7Å
96S98.2Very high97.9Very high1 Ų130.1 Ų30.11%0.00716%0.155CC..Iπ-helixtrans-58.4-42.5177.2-59.70000112.3T86 K91 P92 Y93 L101T86-S96 WeakPolarHBondContact OG1-CB 3.33Å; T86-S96 PolarHBondContact OG1-OG 3.31Å; K91-S96 WeakPolarHBondContact CD-OG 3.44Å; K91-S96 WeakPolarHBondContact CG-OG 3.48Å; P92-S96 PolarHBondContact O-N 3.38Å; Y93-S96 PolarHBondContact O-N 3.32Å; S96-L101 WeakPolarHBondContact O-CB 3.5Å; S96-L101 PolarHBondContact O-N 2.89Å
97L97.8Very high97.9Very high55 Ų5530.2 Ų30.229%0.28816%0.155SC..Iπ-helixtrans-76.9-51.7-177.9-17766.2000112.7R78 A82 Y93 H95 L101R78-L97 HydrophobicContact CB-CD1 4.35Å; A82-L97 HydrophobicContact CB-CB 3.83Å; A82-L97 HydrophobicContact CB-CD1 3.89Å; A82-L97 HydrophobicContact CB-CG 4.47Å; Y93-L97 HydrophobicContact CE1-CB 4.33Å; Y93-L97 HydrophobicContact CE1-CD2 3.8Å; Y93-L97 WeakPolarHBondContact O-CB 3.32Å; Y93-L97 PolarHBondContact O-N 3.11Å; H95-L97 VanDerWaalsContact C-N 3.3Å; H95-L97 PolarHBondContact O-N 2.88Å; L97-L101 HydrophobicContact CD1-CD2 4.31Å
98A96.3Very high97.9Very high62 Ų6227.8 Ų27.851%0.51214%0.142SC..Iπ-helixtrans-88.6-16.3-16900000114V94V94-A98 WeakPolarHBondContact O-CB 3.39Å; V94-A98 PolarHBondContact O-N 3.01Å
99I96.5Very high97.9Very high60 Ų6031.1 Ų31.131%0.30816%0.155SC..Iπ-helixtrans-118.3-68.1-176.5-56.2170.3000109.8H95 L101 E102 L103 F302H95-I99 HydrophobicContact CB-CD1 4.42Å; H95-I99 WeakPolarHBondContact O-CA 3.38Å; H95-I99 VanDerWaalsContact O-CB 3.3Å; H95-I99 WeakPolarHBondContact O-CB 3.45Å; H95-I99 PolarHBondContact O-N 3.21Å; I99-L101 PolarHBondContact O-N 2.89Å; I99-E102 PolarHBondContact O-N 2.98Å; I99-L103 HydrophobicContact CG2-CD1 3.83Å; I99-L103 VanDerWaalsContact O-CB 3.29Å; I99-L103 WeakPolarHBondContact O-CB 3.48Å; I99-L103 VanDerWaalsContact O-CG 3.23Å; I99-L103 WeakPolarHBondContact O-CG 3.46Å; I99-L103 PolarHBondContact O-N 2.89Å; I99-F302 HydrophobicContact CD1-CE2 3.49Å; I99-F302 VanDerWaalsContact CD1-CE2 3.49Å; I99-F302 HydrophobicContact CD1-CZ 3.78Å; I99-F302 HydrophobicContact CG2-CZ 4.16Å
100D97.6Very high98Very high1 Ų133.3 Ų33.31%0.00516%0.163CC..Iπ-helixtrans-59.8-55.1-171.3-72.829.3000112.5K91 H95 L103 A104 F149K91-D100 IonicContact NZ-OD1 3.97Å; K91-D100 IonicContact NZ-OD2 3.05Å; K91-D100 PolarHBondContact NZ-OD2 3.03Å; H95-D100 PolarHBondContact O-N 3.35Å; H95-D100 VanDerWaalsContact O-N 3.13Å; D100-L103 PolarHBondContact O-N 3.32Å; D100-A104 VanDerWaalsContact O-CB 3.29Å; D100-A104 WeakPolarHBondContact O-CB 3.4Å; D100-A104 PolarHBondContact O-N 3.47Å; D100-F149 VanDerWaalsContact OD1-CD1 3.31Å; D100-F149 WeakPolarHBondContact OD1-CD1 3.32Å; D100-F149 WeakPolarHBondContact OD1-CE1 3.23Å; D100-F149 VanDerWaalsContact OD2-CD1 3.31Å; D100-F149 WeakPolarHBondContact OD2-CD1 3.45Å
101L98Very high98Very high4 Ų433.3 Ų33.32%0.02116%0.163CC..Iπ-helixtrans-65.5-43.8-177.9-179.771.6000111.7M74 R78 L81 S96 L97 I99 L103 A104 I105 L151M74-L101 HydrophobicContact CE-CD1 4.08Å; R78-L101 HydrophobicContact CB-CD2 3.25Å; L81-L101 HydrophobicContact CB-CD1 4.09Å; L81-L101 HydrophobicContact CD1-CD1 3.85Å; S96-L101 WeakPolarHBondContact O-CB 3.5Å; S96-L101 PolarHBondContact O-N 2.89Å; L97-L101 HydrophobicContact CD1-CD2 4.31Å; I99-L101 PolarHBondContact O-N 2.89Å; L101-L103 PolarHBondContact O-N 3.36Å; L101-A104 WeakPolarHBondContact O-CB 3.36Å; L101-A104 PolarHBondContact O-N 3.5Å; L101-I105 HydrophobicContact CD1-CD1 4.03Å; L101-I105 HydrophobicContact CD1-CG1 4.33Å; L101-I105 HydrophobicContact CD2-CD1 4.3Å; L101-I105 HydrophobicContact CG-CD1 3.78Å; L101-I105 HydrophobicContact CG-CG1 4.42Å; L101-I105 WeakPolarHBondContact O-CB 3.41Å; L101-I105 VanDerWaalsContact O-CG1 3.31Å; L101-I105 WeakPolarHBondContact O-CG1 3.35Å; L101-I105 PolarHBondContact O-N 3.47Å; L101-L151 HydrophobicContact CB-CD2 4.43Å; L101-L151 HydrophobicContact CD1-CD2 3.52Å
102E97.8Very high98Very high61 Ų6133.5 Ų33.529%0.28517%0.165SC..Hα-helixtrans-60.9-46.5179.1-179.462-164.800111I99 A104 I105 R106I99-E102 PolarHBondContact O-N 2.98Å; E102-A104 VanDerWaalsContact C-N 3.34Å; E102-A104 PolarHBondContact O-N 2.97Å; E102-I105 PolarHBondContact O-N 3.37Å; E102-R106 WeakPolarHBondContact O-CB 3.31Å; E102-R106 VanDerWaalsContact O-CG 3.27Å; E102-R106 WeakPolarHBondContact O-CG 3.15Å; E102-R106 PolarHBondContact O-N 2.83Å; E102-R106 IonicContact OE1-CZ 3.6Å; E102-R106 IonicContact OE1-NE 3.93Å; E102-R106 PolarHBondContact OE1-NE 2.84Å; E102-R106 IonicContact OE1-NH2 2.66Å; E102-R106 PolarHBondContact OE1-NH2 3.1Å
103L98.2Very high98Very high36 Ų3634.7 Ų34.719%0.18818%0.178CC..Hα-helixtrans-66.4-35.5176.4-68.9176.3000112.1I99 D100 L101 C107 L152I99-L103 HydrophobicContact CG2-CD1 3.83Å; I99-L103 VanDerWaalsContact O-CB 3.29Å; I99-L103 WeakPolarHBondContact O-CB 3.48Å; I99-L103 VanDerWaalsContact O-CG 3.23Å; I99-L103 WeakPolarHBondContact O-CG 3.46Å; I99-L103 PolarHBondContact O-N 2.89Å; D100-L103 PolarHBondContact O-N 3.32Å; L101-L103 PolarHBondContact O-N 3.36Å; L103-C107 VanDerWaalsContact O-CB 3.24Å; L103-C107 WeakPolarHBondContact O-CB 2.85Å; L103-C107 PolarHBondContact O-N 2.92Å; L103-L152 HydrophobicContact CB-CD1 3.5Å; L103-L152 VanDerWaalsContact CB-CD1 3.5Å; L103-L152 HydrophobicContact CD1-CD2 4.35Å
104A98.6Very high98Very high0 Ų034.4 Ų34.40%018%0.177CC..Hα-helixtrans-64.2-48175.500000111.7M74 D100 L101 E102 C107 L108 L151 L152 A155M74-A104 HydrophobicContact CE-CB 3.99Å; D100-A104 VanDerWaalsContact O-CB 3.29Å; D100-A104 WeakPolarHBondContact O-CB 3.4Å; D100-A104 PolarHBondContact O-N 3.47Å; L101-A104 WeakPolarHBondContact O-CB 3.36Å; L101-A104 PolarHBondContact O-N 3.5Å; E102-A104 VanDerWaalsContact C-N 3.34Å; E102-A104 PolarHBondContact O-N 2.97Å; A104-C107 WeakPolarHBondContact O-CB 3.47Å; A104-C107 PolarHBondContact O-N 3.46Å; A104-L108 PolarHBondContact O-N 2.99Å; A104-L151 HydrophobicContact CB-CG 4.27Å; A104-L152 HydrophobicContact CB-CD1 4.28Å; A104-A155 HydrophobicContact CB-CB 3.75Å
105I98.7Very high98.1Very high3 Ų330.7 Ų30.72%0.01515%0.154CC..Hα-helixtrans-61.1-47.1176.8-70.4167.9000110.4A71 M74 E75 L101 E102 C107 L108 R109A71-I105 HydrophobicContact CB-CG2 4.26Å; M74-I105 HydrophobicContact CB-CD1 4.41Å; M74-I105 HydrophobicContact CB-CG1 4.02Å; M74-I105 HydrophobicContact CE-CG1 4.37Å; E75-I105 HydrophobicContact CB-CD1 3.92Å; E75-I105 HydrophobicContact CG-CD1 4.41Å; L101-I105 HydrophobicContact CD1-CD1 4.03Å; L101-I105 HydrophobicContact CD1-CG1 4.33Å; L101-I105 HydrophobicContact CD2-CD1 4.3Å; L101-I105 HydrophobicContact CG-CD1 3.78Å; L101-I105 HydrophobicContact CG-CG1 4.42Å; L101-I105 WeakPolarHBondContact O-CB 3.41Å; L101-I105 VanDerWaalsContact O-CG1 3.31Å; L101-I105 WeakPolarHBondContact O-CG1 3.35Å; L101-I105 PolarHBondContact O-N 3.47Å; E102-I105 PolarHBondContact O-N 3.37Å; I105-C107 VanDerWaalsContact C-N 3.32Å; I105-C107 PolarHBondContact O-N 2.59Å; I105-L108 PolarHBondContact O-N 2.75Å; I105-R109 VanDerWaalsContact CG2-NH1 3.31Å; I105-R109 WeakPolarHBondContact O-CG 3.12Å; I105-R109 PolarHBondContact O-N 3.1Å
106R98.4Very high98.1Very high132 Ų13232.8 Ų32.850%0.49817%0.166SC..Hα-helixtrans-60.3-40.8176.5-74.3179.7-174.4-167.47.1112.3E102 R109 Y110E102-R106 WeakPolarHBondContact O-CB 3.31Å; E102-R106 VanDerWaalsContact O-CG 3.27Å; E102-R106 WeakPolarHBondContact O-CG 3.15Å; E102-R106 PolarHBondContact O-N 2.83Å; E102-R106 IonicContact OE1-CZ 3.6Å; E102-R106 IonicContact OE1-NE 3.93Å; E102-R106 PolarHBondContact OE1-NE 2.84Å; E102-R106 IonicContact OE1-NH2 2.66Å; E102-R106 PolarHBondContact OE1-NH2 3.1Å; R106-R109 PolarHBondContact O-N 3.07Å; R106-Y110 VanDerWaalsContact O-CB 3.29Å; R106-Y110 WeakPolarHBondContact O-CB 3.25Å; R106-Y110 PolarHBondContact O-N 3.06Å
107C98.7Very high98.1Very high1 Ų137.4 Ų37.41%0.00719%0.187CC..Hα-helixtrans-62-46.4177.4-176.40000111.8L103 A104 I105 Y110 Y111 A155L103-C107 VanDerWaalsContact O-CB 3.24Å; L103-C107 WeakPolarHBondContact O-CB 2.85Å; L103-C107 PolarHBondContact O-N 2.92Å; A104-C107 WeakPolarHBondContact O-CB 3.47Å; A104-C107 PolarHBondContact O-N 3.46Å; I105-C107 VanDerWaalsContact C-N 3.32Å; I105-C107 PolarHBondContact O-N 2.59Å; C107-Y110 PolarHBondContact O-N 3.25Å; C107-Y111 WeakPolarHBondContact O-CD2 3.42Å; C107-Y111 PolarHBondContact O-N 2.95Å; C107-A155 HydrophobicContact CB-CB 4.49Å
108L98.7Very high98.1Very high1 Ų136.5 Ų36.51%0.00518%0.182CC..Hα-helixtrans-61.6-45.4175.6-68.5176.9000111.8L67 L70 A71 M74 A104 I105 Y110 Y111 A112 A155 I158L67-L108 HydrophobicContact CD2-CD2 4.13Å; L70-L108 HydrophobicContact CD2-CD1 4.06Å; L70-L108 HydrophobicContact CD2-CD2 4.47Å; L70-L108 HydrophobicContact CG-CD1 4.03Å; A71-L108 HydrophobicContact CB-CB 3.99Å; A71-L108 HydrophobicContact CB-CD1 4.41Å; M74-L108 HydrophobicContact CE-CD1 4.33Å; M74-L108 HydrophobicContact SD-CD1 3.35Å; M74-L108 WeakPolarHBondContact SD-CD1 3.26Å; A104-L108 PolarHBondContact O-N 2.99Å; I105-L108 PolarHBondContact O-N 2.75Å; L108-Y110 VanDerWaalsContact C-N 3.33Å; L108-Y110 PolarHBondContact O-N 3.32Å; L108-Y111 PolarHBondContact O-N 2.89Å; L108-A112 VanDerWaalsContact O-CB 3.3Å; L108-A112 WeakPolarHBondContact O-CB 3.31Å; L108-A112 PolarHBondContact O-N 3.15Å; L108-A155 HydrophobicContact CD2-CB 4.42Å; L108-A155 HydrophobicContact CG-CB 4.24Å; L108-I158 HydrophobicContact CD2-CG1 4.19Å
109R98.6Very high98.1Very high70 Ų7040 Ų4026%0.26419%0.187SC..Hα-helixtrans-62.1-39.5176.9-72.3176.4170.3156.4-2.5112.1A71 D72 E75 I105 R106 A112 G113A71-R109 HydrophobicContact CB-CG 3.72Å; D72-R109 IonicContact OD1-CZ 2.88Å; D72-R109 IonicContact OD1-NE 3.26Å; D72-R109 IonicContact OD1-NH2 3.63Å; D72-R109 PolarHBondContact OD1-NH2 2.96Å; E75-R109 VanDerWaalsContact CD-NH2 3.33Å; E75-R109 IonicContact OE1-CZ 2.65Å; E75-R109 IonicContact OE1-NH1 2.64Å; E75-R109 PolarHBondContact OE1-NH1 2.92Å; E75-R109 IonicContact OE1-NH2 3.97Å; E75-R109 IonicContact OE2-CZ 2.71Å; E75-R109 IonicContact OE2-NH1 3.76Å; E75-R109 IonicContact OE2-NH2 3.91Å; E75-R109 PolarHBondContact OE2-NH2 3.5Å; I105-R109 VanDerWaalsContact CG2-NH1 3.31Å; I105-R109 WeakPolarHBondContact O-CG 3.12Å; I105-R109 PolarHBondContact O-N 3.1Å; R106-R109 PolarHBondContact O-N 3.07Å; R109-A112 WeakPolarHBondContact O-CB 3.47Å; R109-G113 PolarHBondContact O-N 3.42Å
110Y98.7Very high98.1Very high46 Ų4638.6 Ų38.618%0.1819%0.187CC..Hα-helixtrans-62.5-50.9176.3173.5-102.7000111.6R106 C107 L108 A112 G113 W114 A467 T468 G484 Q485R106-Y110 VanDerWaalsContact O-CB 3.29Å; R106-Y110 WeakPolarHBondContact O-CB 3.25Å; R106-Y110 PolarHBondContact O-N 3.06Å; C107-Y110 PolarHBondContact O-N 3.25Å; L108-Y110 VanDerWaalsContact C-N 3.33Å; L108-Y110 PolarHBondContact O-N 3.32Å; Y110-A112 VanDerWaalsContact C-N 3.34Å; Y110-A112 PolarHBondContact O-N 3.31Å; Y110-G113 PolarHBondContact O-N 3.36Å; Y110-G113 VanDerWaalsContact O-N 3.15Å; Y110-W114 AromaticContact CE1-CD1 3.58Å; Y110-W114 AromaticContact CE1-NE1 3.46Å; Y110-W114 AromaticContact CE2-CD1 3.97Å; Y110-W114 AromaticContact CE2-NE1 3.39Å; Y110-W114 AromaticContact CZ-CD1 3.58Å; Y110-W114 AromaticContact CZ-NE1 2.97Å; Y110-W114 PolarHBondContact O-N 2.81Å; Y110-W114 PolarHBondContact OH-NE1 3.42Å; Y110-A467 HydrophobicContact CD1-CB 3.95Å; Y110-A467 WeakPolarHBondContact CD1-O 3.18Å; Y110-A467 HydrophobicContact CD2-CB 4.46Å; Y110-A467 WeakPolarHBondContact CE1-O 3.26Å; Y110-A467 HydrophobicContact CG-CB 3.78Å; Y110-T468 HydrophobicContact CD2-CG2 3.93Å; Y110-T468 HydrophobicContact CE2-CG2 3.6Å; Y110-G484 VanDerWaalsContact OH-C 3.31Å; Y110-G484 WeakPolarHBondContact OH-CA 3.27Å; Y110-Q485 PolarHBondContact OH-N 2.81Å
111Y98.7Very high98.1Very high0 Ų046 Ų460%022%0.219CC..Hα-helixtrans-71.8-27.1-180-78.1-60.2000113.8C107 L108 G113 W114 A115 P160 A163 L483 G484 L488C107-Y111 WeakPolarHBondContact O-CD2 3.42Å; C107-Y111 PolarHBondContact O-N 2.95Å; L108-Y111 PolarHBondContact O-N 2.89Å; Y111-G113 PolarHBondContact O-N 3.2Å; Y111-W114 PolarHBondContact O-N 3.27Å; Y111-A115 PolarHBondContact O-N 2.88Å; Y111-P160 HydrophobicContact CD1-CB 3.92Å; Y111-P160 HydrophobicContact CD2-CB 4.32Å; Y111-P160 HydrophobicContact CD2-CG 4.3Å; Y111-P160 HydrophobicContact CE1-CB 3.63Å; Y111-P160 HydrophobicContact CE1-CG 4.36Å; Y111-P160 HydrophobicContact CE2-CB 4.01Å; Y111-P160 VanDerWaalsContact CE2-CD 3.49Å; Y111-P160 HydrophobicContact CE2-CG 3.85Å; Y111-P160 HydrophobicContact CG-CB 4.24Å; Y111-A163 WeakPolarHBondContact O-CB 3.48Å; Y111-L483 HydrophobicContact CE2-CD2 4.36Å; Y111-L483 WeakPolarHBondContact OH-CA 3.47Å; Y111-L483 PolarHBondContact OH-N 3.45Å; Y111-L483 VanDerWaalsContact OH-N 3.14Å; Y111-L483 PolarHBondContact OH-O 2.64Å; Y111-G484 PolarHBondContact OH-O 2.82Å; Y111-L488 HydrophobicContact CD1-CD2 3.7Å; Y111-L488 HydrophobicContact CD1-CG 4.46Å; Y111-L488 HydrophobicContact CE1-CD2 3.61Å; Y111-L488 HydrophobicContact CE1-CG 3.99Å
112A98.4Very high98.1Very high4 Ų450.8 Ų50.83%0.03325%0.249CC..Hα-helixtrans-55.7-43.7167.800000111.3G64 L67 H68 L108 R109 Y110 W114 A115G64-A112 WeakPolarHBondContact CA-O 3.22Å; G64-A112 WeakPolarHBondContact O-CB 3.43Å; L67-A112 HydrophobicContact CB-CB 3.61Å; L67-A112 HydrophobicContact CD1-CB 4.5Å; H68-A112 VanDerWaalsContact CD2-CB 3.44Å; H68-A112 WeakPolarHBondContact CD2-CB 3.33Å; H68-A112 WeakPolarHBondContact NE2-CB 3.12Å; L108-A112 VanDerWaalsContact O-CB 3.3Å; L108-A112 WeakPolarHBondContact O-CB 3.31Å; L108-A112 PolarHBondContact O-N 3.15Å; R109-A112 WeakPolarHBondContact O-CB 3.47Å; Y110-A112 VanDerWaalsContact C-N 3.34Å; Y110-A112 PolarHBondContact O-N 3.31Å; A112-W114 PolarHBondContact O-N 3.09Å; A112-A115 WeakPolarHBondContact O-CB 3.26Å; A112-A115 PolarHBondContact O-N 3.48Å
113G98.3Very high98Very high28 Ų2850.9 Ų50.929%0.28925%0.251SS..Hα-helixtrans-65.5-20.6175.300000114.7R109 Y110 Y111 K117R109-G113 PolarHBondContact O-N 3.42Å; Y110-G113 PolarHBondContact O-N 3.36Å; Y110-G113 VanDerWaalsContact O-N 3.15Å; Y111-G113 PolarHBondContact O-N 3.2Å; G113-K117 WeakPolarHBondContact O-CD 3.16Å; G113-K117 WeakPolarHBondContact O-CE 3.43Å; G113-K117 PolarHBondContact O-NZ 3.02Å
114W98.5Very high97.7Very high49 Ų4955.7 Ų55.719%0.18629%0.285CS..Hα-helixtrans-88.5-18.7177-84.5103.2000114.4Y110 Y111 A112 D116 K117 I118 Q485 L488Y110-W114 AromaticContact CE1-CD1 3.58Å; Y110-W114 AromaticContact CE1-NE1 3.46Å; Y110-W114 AromaticContact CE2-CD1 3.97Å; Y110-W114 AromaticContact CE2-NE1 3.39Å; Y110-W114 AromaticContact CZ-CD1 3.58Å; Y110-W114 AromaticContact CZ-NE1 2.97Å; Y110-W114 PolarHBondContact O-N 2.81Å; Y110-W114 PolarHBondContact OH-NE1 3.42Å; Y111-W114 PolarHBondContact O-N 3.27Å; A112-W114 PolarHBondContact O-N 3.09Å; W114-D116 PolarHBondContact O-N 2.88Å; W114-K117 HydrophobicContact CE3-CB 3.74Å; W114-K117 HydrophobicContact CZ3-CB 4.08Å; W114-K117 PolarHBondContact O-N 2.9Å; W114-I118 WeakPolarHBondContact O-CG1 3.42Å; W114-Q485 HydrophobicContact CH2-CB 3.93Å; W114-Q485 HydrophobicContact CH2-CG 3.6Å; W114-Q485 HydrophobicContact CZ2-CB 3.81Å; W114-Q485 HydrophobicContact CZ2-CG 4.02Å; W114-Q485 HydrophobicContact CZ3-CG 4.12Å; W114-L488 HydrophobicContact CB-CD1 4.04Å; W114-L488 HydrophobicContact CB-CD2 4.44Å; W114-L488 HydrophobicContact CD2-CD1 3.58Å; W114-L488 HydrophobicContact CE3-CD1 3.58Å; W114-L488 HydrophobicContact CG-CD1 3.8Å; W114-L488 HydrophobicContact CZ3-CD1 4.27Å
115A97.9Very high97.4Very high2 Ų258.7 Ų58.72%0.01730%0.303CS..THydrogen-bonded Turntrans-53.5-32.9-169.100000113.4P60 R63 Y111 A112 A163P60-A115 VanDerWaalsContact CB-O 3.32Å; P60-A115 WeakPolarHBondContact CB-O 3.05Å; P60-A115 VanDerWaalsContact O-CB 3.3Å; P60-A115 WeakPolarHBondContact O-CB 3.46Å; R63-A115 HydrophobicContact CB-CB 4.25Å; R63-A115 PolarHBondContact NH2-O 3.24Å; Y111-A115 PolarHBondContact O-N 2.88Å; A112-A115 WeakPolarHBondContact O-CB 3.26Å; A112-A115 PolarHBondContact O-N 3.48Å; A115-A163 HydrophobicContact CB-CB 4.21Å
116D97.3Very high96.9Very high72 Ų7261.5 Ų61.539%0.38532%0.323SS..THydrogen-bonded Turntrans-105.27.6177.669.2-9.6000115.2P60 C61 W114P60-D116 HydrophobicContact CB-CB 3.86Å; C61-D116 HydrophobicContact CB-CB 4.38Å; W114-D116 PolarHBondContact O-N 2.88Å
117K98.1Very high96.3Very high99 Ų9961 Ų6143%0.4334%0.336SS..  trans-112.111.9179.9-68.1169.7-164.662.70113.2G113 W114 H119G113-K117 WeakPolarHBondContact O-CD 3.16Å; G113-K117 WeakPolarHBondContact O-CE 3.43Å; G113-K117 PolarHBondContact O-NZ 3.02Å; W114-K117 HydrophobicContact CE3-CB 3.74Å; W114-K117 HydrophobicContact CZ3-CB 4.08Å; W114-K117 PolarHBondContact O-N 2.9Å; K117-H119 PolarHBondContact O-N 3.37Å; K117-H119 PolarHBondContact O-ND1 3.06Å
118I97.2Very high95.6Very high36 Ų3662.8 Ų62.819%0.18534%0.344CS..  trans-87.199176.5-63.4156.6000108.7W114 R135 C164 L488 T492W114-I118 WeakPolarHBondContact O-CG1 3.42Å; I118-R135 HydrophobicContact CG2-CB 3.67Å; I118-R135 HydrophobicContact CG2-CG 4.44Å; I118-C164 HydrophobicContact CD1-CB 4.31Å; I118-C164 VanDerWaalsContact CD1-SG 3.56Å; I118-L488 HydrophobicContact CD1-CD2 4.33Å; I118-L488 HydrophobicContact CG1-CD1 4.2Å; I118-T492 HydrophobicContact CG2-CG2 3.97Å
119H97.1Very high95.2Very high134 Ų13466.7 Ų66.762%0.6236%0.36SS*.  trans-108.4146.9-173.5-53.7131.1000113.4K117 R135K117-H119 PolarHBondContact O-N 3.37Å; K117-H119 PolarHBondContact O-ND1 3.06Å; H119-R135 VanDerWaalsContact O-CG 3.26Å; H119-R135 WeakPolarHBondContact O-CG 3.3Å
120G96.8Very high94.9Very high31 Ų3167.3 Ų67.332%0.3236%0.364SS..  trans-77.1-165.7159.100000112.5T133G120-T133 VanDerWaalsContact CA-O 3.31Å; G120-T133 WeakPolarHBondContact CA-O 3.5Å
121K97.6Very high94.7Very high156 Ų15665.1 Ų65.168%0.67836%0.356SS*.  trans-134.3147.3178.9-61.4-176.2179.3-178.60110.2L123 Y132 T133K121-L123 HydrophobicContact CB-CD2 4.18Å; K121-Y132 CarbonylContact O-C 3.57Å; K121-Y132 WeakPolarHBondContact O-CA 3.36Å; K121-T133 PolarHBondContact N-OG1 3.5Å; K121-T133 PolarHBondContact O-N 3.18Å
122T97Very high94.6Very high106 Ų10668.9 Ų68.965%0.6537%0.371SS*.EExtended strand (participates in β ladder)trans-86.3137.1160.650.60000109.1F130T122-F130 HydrophobicContact CG2-CE2 4.27Å; T122-F130 HydrophobicContact CG2-CZ 4.41Å
123L95.7Very high94.6Very high62 Ų6269.8 Ų69.833%0.32538%0.375SS..EExtended strand (participates in β ladder)trans-111132.3-171.5-54.9178.8000111.1K121 V125 A131 T133K121-L123 HydrophobicContact CB-CD2 4.18Å; L123-V125 HydrophobicContact CB-CG1 4.19Å; L123-V125 PolarHBondContact O-N 3.46Å; L123-A131 HydrophobicContact CB-CB 4.07Å; L123-A131 HydrophobicContact CD1-CB 4.36Å; L123-A131 PolarHBondContact N-O 2.91Å; L123-T133 HydrophobicContact CD1-CG2 3.96Å; L123-T133 HydrophobicContact CD2-CG2 4.42Å; L123-T133 HydrophobicContact CG-CG2 4.38Å
124P93.9Very high94.6Very high138 Ų13874.2 Ų74.290%0.89638%0.384SS*.  trans-78.870.9178.134-35.6000110.8
125V90.5Very high94.5Very high63 Ų6375.5 Ų75.538%0.38239%0.388SS..  trans-81.1177.8174.1-63.10000110.9L123 Y129 A131L123-V125 HydrophobicContact CB-CG1 4.19Å; L123-V125 PolarHBondContact O-N 3.46Å; V125-Y129 WeakPolarHBondContact CG2-O 3.45Å; V125-A131 HydrophobicContact CB-CB 4.32Å; V125-A131 HydrophobicContact CG1-CB 3.67Å; V125-A131 HydrophobicContact CG2-CB 3.65Å
126S89.1Confident94.5Very high62 Ų6276.9 Ų76.943%0.43439%0.394SS..  trans-46.7138172.8171.20000111.2K128 Y129S126-K128 PolarHBondContact O-N 3Å; S126-Y129 PolarHBondContact O-N 2.79Å
127P84.9Confident94.5Very high120 Ų12074.4 Ų74.478%0.77938%0.382SS*.THydrogen-bonded Turntrans-53.9-23.3-175.8-28.334.7000115.3Y129 S501P127-Y129 PolarHBondContact O-N 2.71Å; P127-S501 PolarHBondContact O-OG 2.87Å
128K84.8Confident94.5Very high39 Ų3970.6 Ų70.617%0.1737%0.367CS..THydrogen-bonded Turntrans-63-19.6174.9-66.2174.9169.7-1790113.8S126 S501 V509 E513S126-K128 PolarHBondContact O-N 3Å; K128-S501 VanDerWaalsContact C-OG 3.29Å; K128-S501 WeakPolarHBondContact O-CB 3.49Å; K128-S501 PolarHBondContact O-N 3.38Å; K128-S501 PolarHBondContact O-OG 2.8Å; K128-V509 HydrophobicContact CD-CG1 4.16Å; K128-E513 IonicContact NZ-OE1 2.69Å; K128-E513 PolarHBondContact NZ-OE1 2.97Å
129Y89.4Confident94.6Very high84 Ų8469.3 Ų69.333%0.32936%0.363SS..EExtended strand (participates in β ladder)trans-124.8147-174.7-58.5-77.1000111.5V125 S126 P127 R499 I500 S501V125-Y129 WeakPolarHBondContact CG2-O 3.45Å; S126-Y129 PolarHBondContact O-N 2.79Å; P127-Y129 PolarHBondContact O-N 2.71Å; Y129-R499 CarbonylContact C-O 3.54Å; Y129-R499 VanDerWaalsContact CA-O 3.27Å; Y129-R499 WeakPolarHBondContact CA-O 3.49Å; Y129-I500 HydrophobicContact CD1-CG1 4.19Å; Y129-I500 HydrophobicContact CE1-CG1 3.92Å; Y129-S501 WeakPolarHBondContact CA-OG 3.44Å; Y129-S501 PolarHBondContact N-OG 2.99Å; Y129-S501 PolarHBondContact O-OG 2.89Å
130F92.2Very high94.6Very high83 Ų8363 Ų6336%0.36433%0.334SS..EExtended strand (participates in β ladder)trans-107.1121.6162.9172.8-111.3000108.4T122 Y132 S498 R499 S501T122-F130 HydrophobicContact CG2-CE2 4.27Å; T122-F130 HydrophobicContact CG2-CZ 4.41Å; F130-Y132 HydrophobicContact CD1-CD1 4.23Å; F130-Y132 AromaticContact CE1-CD1 3.62Å; F130-Y132 HydrophobicContact CE1-CD1 3.62Å; F130-Y132 HydrophobicContact CE1-CE1 4.24Å; F130-Y132 HydrophobicContact CE1-CG 4.4Å; F130-Y132 HydrophobicContact CZ-CD1 4.22Å; F130-S498 WeakPolarHBondContact O-CA 3.45Å; F130-R499 HydrophobicContact CB-CG 4.08Å; F130-R499 HydrophobicContact CD1-CG 4.1Å; F130-R499 PolarHBondContact N-O 3.23Å; F130-R499 PolarHBondContact O-N 2.87Å; F130-S501 PolarHBondContact N-OG 3.5Å
131A95.4Very high94.7Very high0 Ų061.5 Ų61.50%032%0.319CS..EExtended strand (participates in β ladder)trans-123.7138.5179.900000111.6L123 V125 V497L123-A131 HydrophobicContact CB-CB 4.07Å; L123-A131 HydrophobicContact CD1-CB 4.36Å; L123-A131 PolarHBondContact N-O 2.91Å; V125-A131 HydrophobicContact CB-CB 4.32Å; V125-A131 HydrophobicContact CG1-CB 3.67Å; V125-A131 HydrophobicContact CG2-CB 3.65Å; A131-V497 WeakPolarHBondContact CA-O 3.27Å
132Y97.4Very high94.8Very high79 Ų7954.1 Ų54.131%0.3129%0.286SS..EExtended strand (participates in β ladder)trans-144.5161.3174.970.9-81.8000111.1K121 F130 R134 V497K121-Y132 CarbonylContact O-C 3.57Å; K121-Y132 WeakPolarHBondContact O-CA 3.36Å; F130-Y132 HydrophobicContact CD1-CD1 4.23Å; F130-Y132 AromaticContact CE1-CD1 3.62Å; F130-Y132 HydrophobicContact CE1-CD1 3.62Å; F130-Y132 HydrophobicContact CE1-CE1 4.24Å; F130-Y132 HydrophobicContact CE1-CG 4.4Å; F130-Y132 HydrophobicContact CZ-CD1 4.22Å; Y132-R134 HydrophobicContact CD2-CG 4.28Å; Y132-R134 HydrophobicContact CE2-CG 3.8Å; Y132-V497 HydrophobicContact CD1-CB 4.14Å; Y132-V497 HydrophobicContact CD1-CG1 4.47Å; Y132-V497 HydrophobicContact CE1-CB 3.62Å; Y132-V497 HydrophobicContact CE1-CG1 3.62Å; Y132-V497 HydrophobicContact CE1-CG2 4.47Å; Y132-V497 HydrophobicContact CE2-CB 4.19Å; Y132-V497 HydrophobicContact CE2-CG2 4.28Å; Y132-V497 PolarHBondContact N-O 3.49Å; Y132-V497 PolarHBondContact O-N 3.25Å
133T98.3Very high94.9Very high22 Ų2249 Ų4914%0.13526%0.255CS..EExtended strand (participates in β ladder)trans-110.8155.3172.566.10000111.8G120 K121 L123 V494 K495G120-T133 VanDerWaalsContact CA-O 3.31Å; G120-T133 WeakPolarHBondContact CA-O 3.5Å; K121-T133 PolarHBondContact N-OG1 3.5Å; K121-T133 PolarHBondContact O-N 3.18Å; L123-T133 HydrophobicContact CD1-CG2 3.96Å; L123-T133 HydrophobicContact CD2-CG2 4.42Å; L123-T133 HydrophobicContact CG-CG2 4.38Å; T133-V494 HydrophobicContact CG2-CG1 4.15Å; T133-K495 CarbonylContact C-O 3.4Å; T133-K495 WeakPolarHBondContact CA-O 3.33Å
134R97.1Very high95Very high122 Ų12246.7 Ų46.746%0.4624%0.243SC..EExtended strand (participates in β ladder)trans-119.5144.5167.3-69.7162.556.3120.70.7108.6Y132 E136 V494 K495Y132-R134 HydrophobicContact CD2-CG 4.28Å; Y132-R134 HydrophobicContact CE2-CG 3.8Å; R134-E136 HydrophobicContact CB-CG 4.09Å; R134-E136 IonicContact CZ-OE1 2.86Å; R134-E136 IonicContact NE-OE1 2.85Å; R134-E136 PolarHBondContact NE-OE1 2.86Å; R134-E136 IonicContact NH2-OE1 3.33Å; R134-E136 PolarHBondContact NH2-OE1 2.79Å; R134-V494 WeakPolarHBondContact O-CA 3.46Å; R134-K495 HydrophobicContact CB-CB 4.43Å; R134-K495 PolarHBondContact N-O 2.95Å; R134-K495 PolarHBondContact O-N 2.87Å
135R97.3Very high95.3Very high76 Ų7640.3 Ų40.329%0.28720%0.201SC..EExtended strand (participates in β ladder)trans-105.193.2171.7-66.3-77.2-83.2-162.8-14.7107.3I118 H119 D489 T492I118-R135 HydrophobicContact CG2-CB 3.67Å; I118-R135 HydrophobicContact CG2-CG 4.44Å; H119-R135 VanDerWaalsContact O-CG 3.26Å; H119-R135 WeakPolarHBondContact O-CG 3.3Å; R135-D489 IonicContact CZ-OD1 3.99Å; R135-D489 IonicContact NH1-OD1 3.77Å; R135-D489 IonicContact NH2-OD1 2.59Å; R135-D489 PolarHBondContact NH2-OD1 3.45Å; R135-T492 HydrophobicContact CB-CG2 4.33Å; R135-T492 PolarHBondContact NE-OG1 2.82Å; R135-T492 VanDerWaalsContact NE-OG1 3.14Å; R135-T492 PolarHBondContact NH1-OG1 2.83Å; R135-T492 PolarHBondContact NH2-OG1 3.46Å
136E97.1Very high95.6Very high30 Ų3038 Ų3814%0.1419%0.187CC..EExtended strand (participates in β ladder)trans-90153.9-177.8-58.9-169.1165.300109.8R134 T492 E493 K495R134-E136 HydrophobicContact CB-CG 4.09Å; R134-E136 IonicContact CZ-OE1 2.86Å; R134-E136 IonicContact NE-OE1 2.85Å; R134-E136 PolarHBondContact NE-OE1 2.86Å; R134-E136 IonicContact NH2-OE1 3.33Å; R134-E136 PolarHBondContact NH2-OE1 2.79Å; E136-T492 CarbonylContact O-C 3.47Å; E136-T492 WeakPolarHBondContact O-CA 3.16Å; E136-E493 PolarHBondContact N-O 3.46Å; E136-E493 PolarHBondContact O-N 2.82Å; E136-K495 IonicContact OE1-NZ 2.67Å; E136-K495 PolarHBondContact OE1-NZ 3.08Å; E136-K495 VanDerWaalsContact OE2-CE 3.3Å; E136-K495 WeakPolarHBondContact OE2-CE 3.34Å; E136-K495 IonicContact OE2-NZ 3.51Å; E136-K495 PolarHBondContact OE2-NZ 3.26Å
137P98Very high96.1Very high20 Ų2036.9 Ų36.913%0.1317%0.174CC..EExtended strand (participates in β ladder)trans-56.8146.7166.622.7-32000110.1R56 G139 C164 G165 N166R56-P137 VanDerWaalsContact CZ-CG 3.45Å; P137-G139 VanDerWaalsContact C-N 3.28Å; P137-G139 PolarHBondContact O-N 2.93Å; P137-C164 WeakPolarHBondContact CB-O 3.34Å; P137-G165 VanDerWaalsContact CB-C 3.49Å; P137-G165 WeakPolarHBondContact CB-O 3.4Å; P137-N166 HydrophobicContact CB-CB 4.49Å; P137-N166 WeakPolarHBondContact CB-OD1 2.88Å
138V98.1Very high96.7Very high20 Ų2031.5 Ų31.512%0.12114%0.138CC..  trans-60.7-41.6172.5-163.60000111N166 D245 K246 Y491V138-N166 WeakPolarHBondContact CA-OD1 3.39Å; V138-N166 PolarHBondContact N-OD1 2.98Å; V138-D245 HydrophobicContact CG1-CB 3.74Å; V138-K246 HydrophobicContact CG1-CB 4.05Å; V138-K246 HydrophobicContact CG2-CD 4.4Å; V138-Y491 WeakPolarHBondContact CG2-O 3.31Å
139G98.3Very high97.4Very high9 Ų930.4 Ų30.49%0.09313%0.134CC..SBendtrans130.7-118.8179.200000111.5P137 N166 T167 D245P137-G139 VanDerWaalsContact C-N 3.28Å; P137-G139 PolarHBondContact O-N 2.93Å; G139-N166 PolarHBondContact N-OD1 2.8Å; G139-N166 WeakPolarHBondContact O-CA 3.47Å; G139-N166 WeakPolarHBondContact O-CB 3.31Å; G139-N166 PolarHBondContact O-OD1 2.7Å; G139-T167 PolarHBondContact O-N 3.27Å; G139-D245 WeakPolarHBondContact CA-OD2 3.49Å
140V98.7Very high97.8Very high1 Ų126.5 Ų26.51%0.00612%0.118CC..EExtended strand (participates in β ladder)trans-87.8119.9176.6178.40000110V42 A45 R46 T167 V169 V244 D245 K246V42-V140 HydrophobicContact CG1-CG1 4.45Å; A45-V140 HydrophobicContact CB-CB 4.49Å; A45-V140 HydrophobicContact CB-CG1 3.86Å; A45-V140 HydrophobicContact CB-CG2 3.78Å; R46-V140 VanDerWaalsContact CD-CG2 3.48Å; R46-V140 HydrophobicContact CG-CG2 3.82Å; V140-T167 WeakPolarHBondContact CA-O 3.43Å; V140-T167 WeakPolarHBondContact CG2-OG1 3.01Å; V140-V169 HydrophobicContact CG1-CG2 4.2Å; V140-V244 HydrophobicContact CG1-CG2 4.29Å; V140-D245 PolarHBondContact N-OD2 3.21Å; V140-D245 PolarHBondContact O-N 3.3Å; V140-K246 PolarHBondContact O-N 2.78Å
141C98.8Very high98.1Very high0 Ų022.7 Ų22.70%010%0.102CC..EExtended strand (participates in β ladder)trans-103.9117.6177.4-61.10000110.7V143 T167 V168 V169 K246 Y491C141-V143 HydrophobicContact CB-CG2 4.44Å; C141-T167 PolarHBondContact N-O 3.5Å; C141-V168 HydrophobicContact CB-CG1 4.28Å; C141-V168 VanDerWaalsContact O-CA 3.32Å; C141-V168 WeakPolarHBondContact O-CA 3.48Å; C141-V169 PolarHBondContact O-N 2.98Å; C141-K246 CarbonylContact C-O 3.39Å; C141-K246 VanDerWaalsContact CA-O 3.32Å; C141-K246 WeakPolarHBondContact CA-O 3.35Å; C141-Y491 HydrophobicContact CB-CE1 4.31Å
142G98.8Very high98.2Very high0 Ų023.2 Ų23.20%010%0.104CC..EExtended strand (participates in β ladder)trans-75.3124.2164.800000110V169 K246 V247 A248G142-V169 WeakPolarHBondContact CA-O 3.41Å; G142-K246 PolarHBondContact N-O 3.36Å; G142-V247 CarbonylContact O-C 3.51Å; G142-V247 VanDerWaalsContact O-CA 3.29Å; G142-V247 WeakPolarHBondContact O-CA 3.41Å; G142-A248 PolarHBondContact O-N 2.85Å
143V98.7Very high98.3Very high0 Ų020.1 Ų20.10%09%0.093CC..EExtended strand (participates in β ladder)trans-121.5109.4-172.3170.70000108C141 I145 K157 V168 V169 V170 K171C141-V143 HydrophobicContact CB-CG2 4.44Å; V143-I145 HydrophobicContact CG1-CG2 4.12Å; V143-K157 HydrophobicContact CG1-CB 3.56Å; V143-K157 HydrophobicContact CG1-CD 3.51Å; V143-K157 HydrophobicContact CG1-CG 4.16Å; V143-K157 HydrophobicContact CG2-CB 4.35Å; V143-V168 HydrophobicContact CG2-CB 4.27Å; V143-V168 HydrophobicContact CG2-CG1 4.23Å; V143-V169 PolarHBondContact N-O 2.69Å; V143-V170 HydrophobicContact CB-CB 4.46Å; V143-V170 HydrophobicContact CB-CG2 4.05Å; V143-V170 HydrophobicContact CG1-CG1 4.19Å; V143-V170 HydrophobicContact CG1-CG2 4.12Å; V143-V170 CarbonylContact O-C 3.49Å; V143-V170 VanDerWaalsContact O-CA 3.29Å; V143-V170 WeakPolarHBondContact O-CA 3.37Å; V143-K171 PolarHBondContact O-N 3.48Å
144I98.8Very high98.3Very high12 Ų1219.2 Ų19.26%0.0629%0.088CC..EExtended strand (participates in β ladder)trans-113.3117.4-179-56.9170.8000108K171 V238 V247 A248 F249 T250 I259I144-K171 HydrophobicContact CG1-CB 4.29Å; I144-K171 HydrophobicContact CG2-CD 4.22Å; I144-V238 HydrophobicContact CD1-CG1 4.47Å; I144-V238 HydrophobicContact CG1-CG1 4.45Å; I144-V247 HydrophobicContact CD1-CG1 4.35Å; I144-A248 PolarHBondContact N-O 3.02Å; I144-F249 HydrophobicContact CB-CD2 3.87Å; I144-F249 HydrophobicContact CD1-CD2 4.46Å; I144-F249 HydrophobicContact CG2-CD2 3.66Å; I144-F249 HydrophobicContact CG2-CE2 4Å; I144-T250 PolarHBondContact O-N 3.4Å; I144-I259 HydrophobicContact CD1-CD1 3.86Å
145I98.6Very high98.4Very high4 Ų413.5 Ų13.52%0.0217%0.066CC..  trans-113.4146.3-174.558.9178000111.9V143 M153 L154 K157 V170 K171 P172 A173V143-I145 HydrophobicContact CG1-CG2 4.12Å; I145-M153 HydrophobicContact CB-CB 4.04Å; I145-M153 HydrophobicContact CG2-CB 3.97Å; I145-L154 HydrophobicContact CD1-CB 3.92Å; I145-L154 HydrophobicContact CD1-CD1 4.3Å; I145-K157 HydrophobicContact CG2-CD 3.6Å; I145-V170 HydrophobicContact CD1-CG1 4.37Å; I145-K171 PolarHBondContact N-O 2.75Å; I145-K171 VanDerWaalsContact N-O 3.17Å; I145-P172 HydrophobicContact CD1-CB 4.12Å; I145-P172 HydrophobicContact CG1-CB 4.21Å; I145-A173 PolarHBondContact O-N 3.32Å
146P98.6Very high98.5Very high14 Ų1410.4 Ų10.49%0.0916%0.055CC..  trans-82.8173.1-179.236.9-39.4000110.8N148 M153 T250P146-N148 WeakPolarHBondContact CB-OD1 3.43Å; P146-N148 WeakPolarHBondContact CG-OD1 3.47Å; P146-M153 HydrophobicContact CG-CB 4.48Å; P146-M153 HydrophobicContact CG-CG 3.85Å; P146-T250 WeakPolarHBondContact CD-O 3.31Å; P146-T250 HydrophobicContact CG-CG2 3.82Å
147W98.6Very high98.5Very high40 Ų409 Ų915%0.1525%0.048CC..SBendtrans-86.1-12.5-176.248.2-104.1000114.8N89 P150 A173 Q175 T176 Q306 I351 H355 F407N89-W147 PolarHBondContact ND2-O 3Å; W147-P150 VanDerWaalsContact O-CD 3.3Å; W147-P150 WeakPolarHBondContact O-CD 3.49Å; W147-P150 VanDerWaalsContact O-CG 3.32Å; W147-P150 WeakPolarHBondContact O-CG 3.27Å; W147-A173 HydrophobicContact CB-CB 3.63Å; W147-A173 HydrophobicContact CG-CB 4.45Å; W147-Q175 HydrophobicContact CB-CB 4.03Å; W147-T176 WeakPolarHBondContact CA-OG1 3.41Å; W147-T176 HydrophobicContact CB-CG2 4.13Å; W147-T176 WeakPolarHBondContact CB-OG1 3.21Å; W147-Q306 HydrophobicContact CH2-CB 3.86Å; W147-Q306 HydrophobicContact CH2-CG 3.86Å; W147-Q306 HydrophobicContact CZ3-CB 3.69Å; W147-Q306 VanDerWaalsContact CZ3-CD 3.42Å; W147-Q306 HydrophobicContact CZ3-CG 3.88Å; W147-I351 HydrophobicContact CB-CD1 4.48Å; W147-I351 HydrophobicContact CB-CG1 4.15Å; W147-I351 HydrophobicContact CD2-CB 3.97Å; W147-I351 HydrophobicContact CD2-CG1 3.83Å; W147-I351 HydrophobicContact CD2-CG2 3.7Å; W147-I351 HydrophobicContact CE3-CB 3.47Å; W147-I351 VanDerWaalsContact CE3-CB 3.47Å; W147-I351 HydrophobicContact CE3-CD1 4.23Å; W147-I351 HydrophobicContact CE3-CG1 3.61Å; W147-I351 HydrophobicContact CE3-CG2 3.59Å; W147-I351 HydrophobicContact CG-CG1 4.05Å; W147-I351 HydrophobicContact CG-CG2 4.48Å; W147-I351 HydrophobicContact CH2-CB 4.13Å; W147-I351 HydrophobicContact CH2-CG2 3.52Å; W147-I351 HydrophobicContact CZ2-CG2 3.65Å; W147-I351 HydrophobicContact CZ3-CB 3.57Å; W147-I351 HydrophobicContact CZ3-CG1 4.25Å; W147-I351 HydrophobicContact CZ3-CG2 3.51Å; W147-H355 AromaticContact CH2-CD2 3.76Å; W147-H355 AromaticContact CH2-NE2 3.85Å; W147-F407 AromaticContact CH2-CD1 3.57Å; W147-F407 HydrophobicContact CH2-CD1 3.57Å; W147-F407 AromaticContact CH2-CE1 3.42Å; W147-F407 HydrophobicContact CH2-CE1 3.42Å; W147-F407 VanDerWaalsContact CH2-CE1 3.42Å; W147-F407 AromaticContact CZ2-CD1 3.87Å; W147-F407 HydrophobicContact CZ2-CD1 3.87Å; W147-F407 AromaticContact CZ2-CE1 3.71Å; W147-F407 HydrophobicContact CZ2-CE1 3.71Å; W147-F407 HydrophobicContact CZ3-CE1 4.11Å
148N98.3Very high98.5Very high7 Ų78.2 Ų8.24%0.0374%0.043CC..SBendtrans-82.8-30.7-16765.9-40.4000114.3K91 P146 N303 Q306 F407K91-N148 WeakPolarHBondContact CE-O 3.24Å; K91-N148 PolarHBondContact NZ-O 3.22Å; P146-N148 WeakPolarHBondContact CB-OD1 3.43Å; P146-N148 WeakPolarHBondContact CG-OD1 3.47Å; N148-N303 PolarHBondContact O-ND2 2.77Å; N148-Q306 HydrophobicContact CB-CB 4.33Å; N148-Q306 WeakPolarHBondContact CB-O 3.44Å; N148-Q306 PolarHBondContact ND2-O 3.41Å; N148-F407 HydrophobicContact CB-CE1 4.09Å; N148-F407 HydrophobicContact CB-CZ 4.23Å; N148-F407 WeakPolarHBondContact ND2-CZ 3.27Å
149F98.5Very high98.6Very high16 Ų167.2 Ų7.27%0.074%0.037CC..SBendtrans-138.364.7169.1-62.9-93.1000110.7D100 L151 L152 M153 F302 N303 V307D100-F149 VanDerWaalsContact OD1-CD1 3.31Å; D100-F149 WeakPolarHBondContact OD1-CD1 3.32Å; D100-F149 WeakPolarHBondContact OD1-CE1 3.23Å; D100-F149 VanDerWaalsContact OD2-CD1 3.31Å; D100-F149 WeakPolarHBondContact OD2-CD1 3.45Å; F149-L151 PolarHBondContact O-N 2.81Å; F149-L152 HydrophobicContact CB-CB 3.99Å; F149-L152 HydrophobicContact CB-CD2 4.4Å; F149-L152 HydrophobicContact CD1-CD2 4.35Å; F149-L152 PolarHBondContact O-N 3.3Å; F149-M153 HydrophobicContact CB-CG 4.23Å; F149-M153 WeakPolarHBondContact O-CB 3.41Å; F149-M153 VanDerWaalsContact O-CG 3.22Å; F149-M153 WeakPolarHBondContact O-CG 3.29Å; F149-M153 PolarHBondContact O-N 3.13Å; F149-F302 AromaticContact CE1-CE1 3.74Å; F149-F302 HydrophobicContact CE1-CE1 3.74Å; F149-F302 HydrophobicContact CE1-CZ 4.05Å; F149-F302 HydrophobicContact CZ-CD1 4.32Å; F149-F302 AromaticContact CZ-CE1 3.6Å; F149-F302 HydrophobicContact CZ-CE1 3.6Å; F149-F302 HydrophobicContact CZ-CZ 4.33Å; F149-N303 HydrophobicContact CE1-CB 4.4Å; F149-N303 HydrophobicContact CE2-CB 4.45Å; F149-N303 WeakPolarHBondContact CE2-ND2 3.19Å; F149-N303 HydrophobicContact CZ-CB 3.75Å; F149-N303 WeakPolarHBondContact CZ-ND2 3.5Å; F149-V307 HydrophobicContact CE2-CB 4.35Å; F149-V307 HydrophobicContact CE2-CG1 4.1Å; F149-V307 HydrophobicContact CE2-CG2 3.99Å; F149-V307 HydrophobicContact CZ-CG1 4.38Å; F149-V307 HydrophobicContact CZ-CG2 3.93Å
150P98.5Very high98.6Very high1 Ų16.9 Ų6.91%0.0063%0.033CC..Hα-helixtrans-53.3-50.7-168.9-24.932.1000113.8E85 W147 L154 T176E85-P150 WeakPolarHBondContact OE1-CD 3.35Å; W147-P150 VanDerWaalsContact O-CD 3.3Å; W147-P150 WeakPolarHBondContact O-CD 3.49Å; W147-P150 VanDerWaalsContact O-CG 3.32Å; W147-P150 WeakPolarHBondContact O-CG 3.27Å; P150-L154 WeakPolarHBondContact O-CB 3.43Å; P150-L154 PolarHBondContact O-N 3.08Å; P150-T176 VanDerWaalsContact CG-CB 3.41Å; P150-T176 HydrophobicContact CG-CG2 3.92Å; P150-T176 VanDerWaalsContact CG-OG1 3.27Å; P150-T176 WeakPolarHBondContact CG-OG1 3.17Å
151L98.3Very high98.6Very high3 Ų36.8 Ų6.82%0.0163%0.032CC..Hα-helixtrans-68.9-40.7-177.2-175.461000112.3M74 L81 E85 L101 A104 F149 L154 A155 V183M74-L151 HydrophobicContact CE-CD1 3.79Å; M74-L151 HydrophobicContact CE-CD2 4.22Å; M74-L151 HydrophobicContact CE-CG 4.11Å; L81-L151 HydrophobicContact CB-CD2 4.32Å; L81-L151 HydrophobicContact CD2-CD1 4.36Å; L81-L151 HydrophobicContact CD2-CD2 4.35Å; E85-L151 VanDerWaalsContact OE1-CB 3.24Å; E85-L151 WeakPolarHBondContact OE1-CB 3.46Å; E85-L151 PolarHBondContact OE1-N 2.96Å; L101-L151 HydrophobicContact CB-CD2 4.43Å; L101-L151 HydrophobicContact CD1-CD2 3.52Å; A104-L151 HydrophobicContact CB-CG 4.27Å; F149-L151 PolarHBondContact O-N 2.81Å; L151-L154 WeakPolarHBondContact O-CB 3.46Å; L151-L154 PolarHBondContact O-N 3.06Å; L151-A155 PolarHBondContact O-N 3.44Å; L151-A155 VanDerWaalsContact O-N 3.1Å; L151-V183 HydrophobicContact CD1-CG2 3.52Å
152L98.4Very high98.6Very high11 Ų116.8 Ų6.86%0.0583%0.032CC..Hα-helixtrans-66.7-46.9179.2-176.260000111.5L103 A104 F149 L154 A155 W156L103-L152 HydrophobicContact CB-CD1 3.5Å; L103-L152 VanDerWaalsContact CB-CD1 3.5Å; L103-L152 HydrophobicContact CD1-CD2 4.35Å; A104-L152 HydrophobicContact CB-CD1 4.28Å; F149-L152 HydrophobicContact CB-CB 3.99Å; F149-L152 HydrophobicContact CB-CD2 4.4Å; F149-L152 HydrophobicContact CD1-CD2 4.35Å; F149-L152 PolarHBondContact O-N 3.3Å; L152-L154 VanDerWaalsContact C-N 3.28Å; L152-L154 PolarHBondContact O-N 3.39Å; L152-A155 PolarHBondContact O-N 3.11Å; L152-W156 HydrophobicContact CD2-CZ2 4.27Å; L152-W156 HydrophobicContact CG-CZ2 4.4Å; L152-W156 PolarHBondContact O-N 2.95Å
153M98.6Very high98.5Very high14 Ų146.8 Ų6.87%0.0693%0.032CC..Hα-helixtrans-66.1-32.6178.8-66.3-6399.600111.9I145 P146 F149 W156 K157 T250I145-M153 HydrophobicContact CB-CB 4.04Å; I145-M153 HydrophobicContact CG2-CB 3.97Å; P146-M153 HydrophobicContact CG-CB 4.48Å; P146-M153 HydrophobicContact CG-CG 3.85Å; F149-M153 HydrophobicContact CB-CG 4.23Å; F149-M153 WeakPolarHBondContact O-CB 3.41Å; F149-M153 VanDerWaalsContact O-CG 3.22Å; F149-M153 WeakPolarHBondContact O-CG 3.29Å; F149-M153 PolarHBondContact O-N 3.13Å; M153-W156 HydrophobicContact CE-CD2 3.73Å; M153-W156 HydrophobicContact CE-CE3 3.61Å; M153-W156 HydrophobicContact CE-CG 4.26Å; M153-W156 HydrophobicContact CE-CH2 4.22Å; M153-W156 HydrophobicContact CE-CZ2 4.32Å; M153-W156 HydrophobicContact CE-CZ3 3.87Å; M153-W156 HydrophobicContact SD-CE3 4.48Å; M153-K157 WeakPolarHBondContact O-CG 3.29Å; M153-K157 PolarHBondContact O-N 2.87Å; M153-T250 HydrophobicContact SD-CG2 4.06Å
154L98.7Very high98.5Very high4 Ų47.1 Ų7.12%0.0214%0.035CC..Hα-helixtrans-59.1-54.4169.517966.2000110.6I145 P150 L151 L152 W156 K157 I158 V170 A180 V183I145-L154 HydrophobicContact CD1-CB 3.92Å; I145-L154 HydrophobicContact CD1-CD1 4.3Å; P150-L154 WeakPolarHBondContact O-CB 3.43Å; P150-L154 PolarHBondContact O-N 3.08Å; L151-L154 WeakPolarHBondContact O-CB 3.46Å; L151-L154 PolarHBondContact O-N 3.06Å; L152-L154 VanDerWaalsContact C-N 3.28Å; L152-L154 PolarHBondContact O-N 3.39Å; L154-W156 VanDerWaalsContact C-N 3.35Å; L154-W156 PolarHBondContact O-N 3.43Å; L154-K157 PolarHBondContact O-N 2.96Å; L154-K157 VanDerWaalsContact O-N 3.16Å; L154-I158 HydrophobicContact CD1-CD1 4.35Å; L154-I158 HydrophobicContact CD1-CG2 3.74Å; L154-I158 HydrophobicContact CG-CD1 4.08Å; L154-I158 HydrophobicContact CG-CG2 4.41Å; L154-I158 WeakPolarHBondContact O-CG1 3.42Å; L154-I158 PolarHBondContact O-N 3.3Å; L154-V170 HydrophobicContact CD1-CG1 3.7Å; L154-V170 HydrophobicContact CD1-CG2 4.16Å; L154-A180 HydrophobicContact CD2-CB 4.1Å; L154-V183 HydrophobicContact CD2-CB 3.82Å; L154-V183 HydrophobicContact CD2-CG1 3.78Å; L154-V183 HydrophobicContact CD2-CG2 4.02Å
155A98.6Very high98.5Very high2 Ų26.8 Ų6.82%0.0173%0.034CC..Hα-helixtrans-59.5-42.4-178.800000112.7A104 C107 L108 L151 L152 K157 G159A104-A155 HydrophobicContact CB-CB 3.75Å; C107-A155 HydrophobicContact CB-CB 4.49Å; L108-A155 HydrophobicContact CD2-CB 4.42Å; L108-A155 HydrophobicContact CG-CB 4.24Å; L151-A155 PolarHBondContact O-N 3.44Å; L151-A155 VanDerWaalsContact O-N 3.1Å; L152-A155 PolarHBondContact O-N 3.11Å; A155-K157 PolarHBondContact O-N 3.46Å; A155-G159 PolarHBondContact O-N 2.87Å
156W98.5Very high98.5Very high11 Ų116.6 Ų6.64%0.0423%0.033CC..Hα-helixtrans-61-28.3178.3-77.228.1000113.4L152 M153 L154 P160 F465 F471 E482 L483L152-W156 HydrophobicContact CD2-CZ2 4.27Å; L152-W156 HydrophobicContact CG-CZ2 4.4Å; L152-W156 PolarHBondContact O-N 2.95Å; M153-W156 HydrophobicContact CE-CD2 3.73Å; M153-W156 HydrophobicContact CE-CE3 3.61Å; M153-W156 HydrophobicContact CE-CG 4.26Å; M153-W156 HydrophobicContact CE-CH2 4.22Å; M153-W156 HydrophobicContact CE-CZ2 4.32Å; M153-W156 HydrophobicContact CE-CZ3 3.87Å; M153-W156 HydrophobicContact SD-CE3 4.48Å; L154-W156 VanDerWaalsContact C-N 3.35Å; L154-W156 PolarHBondContact O-N 3.43Å; W156-P160 WeakPolarHBondContact O-CD 3.29Å; W156-P160 WeakPolarHBondContact O-CG 3.37Å; W156-F465 AromaticContact CH2-CD1 3.62Å; W156-F465 HydrophobicContact CH2-CD1 3.62Å; W156-F465 AromaticContact CH2-CE1 3.8Å; W156-F465 HydrophobicContact CH2-CE1 3.8Å; W156-F465 HydrophobicContact CH2-CG 4.47Å; W156-F465 HydrophobicContact CZ2-CD1 4.05Å; W156-F471 HydrophobicContact CH2-CD1 4.13Å; W156-F471 HydrophobicContact CH2-CG 4.28Å; W156-F471 HydrophobicContact CZ3-CB 4.3Å; W156-F471 AromaticContact CZ3-CD1 3.55Å; W156-F471 HydrophobicContact CZ3-CD1 3.55Å; W156-F471 HydrophobicContact CZ3-CE1 4.12Å; W156-F471 HydrophobicContact CZ3-CG 4.05Å; W156-E482 HydrophobicContact CE3-CB 4.19Å; W156-L483 HydrophobicContact CD2-CD1 4.13Å; W156-L483 HydrophobicContact CD2-CD2 3.77Å; W156-L483 HydrophobicContact CD2-CG 3.96Å; W156-L483 HydrophobicContact CE3-CD1 4.31Å; W156-L483 HydrophobicContact CE3-CD2 4.4Å; W156-L483 HydrophobicContact CE3-CG 4.12Å; W156-L483 HydrophobicContact CG-CD2 3.8Å; W156-L483 HydrophobicContact CG-CG 4.48Å; W156-L483 HydrophobicContact CH2-CD1 3.79Å; W156-L483 HydrophobicContact CH2-CG 4.47Å; W156-L483 HydrophobicContact CZ2-CD1 3.57Å; W156-L483 HydrophobicContact CZ2-CG 4.32Å; W156-L483 HydrophobicContact CZ3-CD1 4.16Å; W156-L483 HydrophobicContact CZ3-CG 4.38Å
157K98.6Very high98.5Very high0 Ų06 Ų60%03%0.029CC..Hα-helixtrans-95.2-45.9-179.9-64.2-177.8-166.9-64.20112.6V143 I145 M153 L154 A155 A161 A248 T250 E482 Y491V143-K157 HydrophobicContact CG1-CB 3.56Å; V143-K157 HydrophobicContact CG1-CD 3.51Å; V143-K157 HydrophobicContact CG1-CG 4.16Å; V143-K157 HydrophobicContact CG2-CB 4.35Å; I145-K157 HydrophobicContact CG2-CD 3.6Å; M153-K157 WeakPolarHBondContact O-CG 3.29Å; M153-K157 PolarHBondContact O-N 2.87Å; L154-K157 PolarHBondContact O-N 2.96Å; L154-K157 VanDerWaalsContact O-N 3.16Å; A155-K157 PolarHBondContact O-N 3.46Å; K157-A161 VanDerWaalsContact O-CB 3.25Å; K157-A161 WeakPolarHBondContact O-CB 3.46Å; K157-A161 PolarHBondContact O-N 2.96Å; K157-A248 HydrophobicContact CD-CB 4.24Å; K157-T250 VanDerWaalsContact CE-OG1 3.28Å; K157-T250 WeakPolarHBondContact CE-OG1 3.33Å; K157-T250 PolarHBondContact NZ-OG1 3.18Å; K157-E482 IonicContact NZ-OE1 2.79Å; K157-E482 PolarHBondContact NZ-OE1 2.72Å; K157-E482 IonicContact NZ-OE2 3.49Å; K157-Y491 PolarHBondContact O-OH 3.1Å
158I98.5Very high98.5Very high3 Ų34 Ų42%0.0152%0.021CC..Hα-helixtrans-74.4-33.1-177.573.8176.2000112.2L70 L108 L154 A161 L162 V168 V170L70-I158 HydrophobicContact CD2-CD1 4.24Å; L108-I158 HydrophobicContact CD2-CG1 4.19Å; L154-I158 HydrophobicContact CD1-CD1 4.35Å; L154-I158 HydrophobicContact CD1-CG2 3.74Å; L154-I158 HydrophobicContact CG-CD1 4.08Å; L154-I158 HydrophobicContact CG-CG2 4.41Å; L154-I158 WeakPolarHBondContact O-CG1 3.42Å; L154-I158 PolarHBondContact O-N 3.3Å; I158-A161 PolarHBondContact O-N 3.46Å; I158-L162 HydrophobicContact CB-CD1 4.05Å; I158-L162 HydrophobicContact CG1-CD1 4.37Å; I158-L162 VanDerWaalsContact O-CB 3.25Å; I158-L162 WeakPolarHBondContact O-CB 3.25Å; I158-L162 WeakPolarHBondContact O-CG 3.49Å; I158-L162 PolarHBondContact O-N 3.47Å; I158-V168 HydrophobicContact CG2-CG2 4.3Å; I158-V170 HydrophobicContact CG2-CG2 4.04Å
159G98.5Very high98.5Very high0 Ų03.7 Ų3.70%02%0.02CC..Hα-helixtrans-52.6-63.1178.200000112.9A155 A161 A163A155-G159 PolarHBondContact O-N 2.87Å; G159-A161 PolarHBondContact O-N 3.33Å; G159-A163 VanDerWaalsContact O-CB 3.31Å; G159-A163 WeakPolarHBondContact O-CB 3.12Å; G159-A163 PolarHBondContact O-N 2.95Å
160P98.6Very high98.6Very high1 Ų13 Ų31%0.0062%0.016CC..Hα-helixtrans-67.1-36.2178.823.5-29.3000112.6Y111 W156 L162 A163 C164 L488 Y491Y111-P160 HydrophobicContact CD1-CB 3.92Å; Y111-P160 HydrophobicContact CD2-CB 4.32Å; Y111-P160 HydrophobicContact CD2-CG 4.3Å; Y111-P160 HydrophobicContact CE1-CB 3.63Å; Y111-P160 HydrophobicContact CE1-CG 4.36Å; Y111-P160 HydrophobicContact CE2-CB 4.01Å; Y111-P160 VanDerWaalsContact CE2-CD 3.49Å; Y111-P160 HydrophobicContact CE2-CG 3.85Å; Y111-P160 HydrophobicContact CG-CB 4.24Å; W156-P160 WeakPolarHBondContact O-CD 3.29Å; W156-P160 WeakPolarHBondContact O-CG 3.37Å; P160-L162 PolarHBondContact O-N 2.99Å; P160-A163 PolarHBondContact O-N 3.1Å; P160-C164 WeakPolarHBondContact O-CB 3.48Å; P160-C164 PolarHBondContact O-N 3.01Å; P160-C164 PolarHBondContact O-SG 2.62Å; P160-L488 HydrophobicContact CB-CD2 4.19Å; P160-Y491 HydrophobicContact CB-CD2 3.68Å; P160-Y491 HydrophobicContact CB-CE2 3.99Å; P160-Y491 HydrophobicContact CB-CG 4.43Å; P160-Y491 HydrophobicContact CG-CD2 3.85Å; P160-Y491 HydrophobicContact CG-CE2 3.59Å
161A98.7Very high98.6Very high0 Ų03.1 Ų3.10%02%0.017CC..Hα-helixtrans-58.9-50.7179.300000111.5K157 I158 G159 C164 G165 N166 V168 Y491K157-A161 VanDerWaalsContact O-CB 3.25Å; K157-A161 WeakPolarHBondContact O-CB 3.46Å; K157-A161 PolarHBondContact O-N 2.96Å; I158-A161 PolarHBondContact O-N 3.46Å; G159-A161 PolarHBondContact O-N 3.33Å; A161-C164 PolarHBondContact O-N 3.31Å; A161-G165 PolarHBondContact O-N 2.92Å; A161-N166 HydrophobicContact CB-CB 4.34Å; A161-N166 VanDerWaalsContact O-CB 3.25Å; A161-N166 WeakPolarHBondContact O-CB 3.4Å; A161-N166 PolarHBondContact O-N 2.72Å; A161-N166 PolarHBondContact O-ND2 3.06Å; A161-V168 HydrophobicContact CB-CG1 3.62Å; A161-Y491 HydrophobicContact CB-CD1 3.62Å; A161-Y491 HydrophobicContact CB-CE1 3.55Å; A161-Y491 HydrophobicContact CB-CG 4.35Å
162L98.5Very high98.6Very high0 Ų03 Ų30%02%0.016CC..Hα-helixtrans-71.5-38.9-178.4-64.6171.8000111.7W55 L67 I158 P160 C164 G165 F219 V223 V224W55-L162 HydrophobicContact CZ2-CB 4.19Å; W55-L162 HydrophobicContact CZ2-CD2 3.92Å; W55-L162 WeakPolarHBondContact CZ2-O 3.47Å; L67-L162 HydrophobicContact CD1-CB 4.46Å; L67-L162 HydrophobicContact CD2-CB 4.03Å; L67-L162 HydrophobicContact CD2-CD1 4.02Å; L67-L162 HydrophobicContact CG-CB 4.48Å; I158-L162 HydrophobicContact CB-CD1 4.05Å; I158-L162 HydrophobicContact CG1-CD1 4.37Å; I158-L162 VanDerWaalsContact O-CB 3.25Å; I158-L162 WeakPolarHBondContact O-CB 3.25Å; I158-L162 WeakPolarHBondContact O-CG 3.49Å; I158-L162 PolarHBondContact O-N 3.47Å; P160-L162 PolarHBondContact O-N 2.99Å; L162-C164 VanDerWaalsContact C-N 3.28Å; L162-C164 PolarHBondContact O-N 3.3Å; L162-G165 PolarHBondContact O-N 3.39Å; L162-F219 HydrophobicContact CD1-CE1 3.89Å; L162-F219 HydrophobicContact CD1-CZ 4.35Å; L162-F219 HydrophobicContact CD2-CE1 4.37Å; L162-V223 HydrophobicContact CD2-CG1 3.5Å; L162-V223 VanDerWaalsContact CD2-CG1 3.5Å; L162-V224 HydrophobicContact CD1-CG2 4.05Å; L162-V224 HydrophobicContact CD2-CG2 3.92Å
163A98.3Very high98.6Very high0 Ų02.7 Ų2.70%02%0.015CC..Hα-helixtrans-57.1-43.4174.700000111.5R63 L67 Y111 A115 G159 P160 G165R63-A163 PolarHBondContact NE-O 3.34Å; R63-A163 PolarHBondContact NH2-O 2.98Å; L67-A163 HydrophobicContact CD1-CB 3.85Å; Y111-A163 WeakPolarHBondContact O-CB 3.48Å; A115-A163 HydrophobicContact CB-CB 4.21Å; G159-A163 VanDerWaalsContact O-CB 3.31Å; G159-A163 WeakPolarHBondContact O-CB 3.12Å; G159-A163 PolarHBondContact O-N 2.95Å; P160-A163 PolarHBondContact O-N 3.1Å; A163-G165 PolarHBondContact O-N 3.5Å
164C98.3Very high98.6Very high7 Ų73.9 Ų3.95%0.0472%0.021CC..THydrogen-bonded Turntrans-71.9-8.5175.9-68.30000114.4I118 P137 P160 A161 L162 N166 Y491 T492I118-C164 HydrophobicContact CD1-CB 4.31Å; I118-C164 VanDerWaalsContact CD1-SG 3.56Å; P137-C164 WeakPolarHBondContact CB-O 3.34Å; P160-C164 WeakPolarHBondContact O-CB 3.48Å; P160-C164 PolarHBondContact O-N 3.01Å; P160-C164 PolarHBondContact O-SG 2.62Å; A161-C164 PolarHBondContact O-N 3.31Å; L162-C164 VanDerWaalsContact C-N 3.28Å; L162-C164 PolarHBondContact O-N 3.3Å; C164-N166 VanDerWaalsContact CB-ND2 3.32Å; C164-N166 WeakPolarHBondContact CB-ND2 3.49Å; C164-Y491 WeakPolarHBondContact CB-O 3.16Å; C164-T492 HydrophobicContact CB-CG2 4.04Å; C164-T492 VanDerWaalsContact SG-CG2 3.56Å
165G97.8Very high98.6Very high4 Ų45.8 Ų5.84%0.0413%0.03CC..THydrogen-bonded Turntrans84.222179.300000114.8W55 P137 A161 L162 A163W55-G165 PolarHBondContact NE1-O 2.87Å; P137-G165 VanDerWaalsContact CB-C 3.49Å; P137-G165 WeakPolarHBondContact CB-O 3.4Å; A161-G165 PolarHBondContact O-N 2.92Å; L162-G165 PolarHBondContact O-N 3.39Å; A163-G165 PolarHBondContact O-N 3.5Å
166N98.7Very high98.6Very high1 Ų15.7 Ų5.71%0.0053%0.029CC..  trans-78.6163.5172.1-59.3-81.9000110.7W55 P137 V138 G139 A161 C164 Y491W55-N166 PolarHBondContact NE1-O 3.47Å; P137-N166 HydrophobicContact CB-CB 4.49Å; P137-N166 WeakPolarHBondContact CB-OD1 2.88Å; V138-N166 WeakPolarHBondContact CA-OD1 3.39Å; V138-N166 PolarHBondContact N-OD1 2.98Å; G139-N166 PolarHBondContact N-OD1 2.8Å; G139-N166 WeakPolarHBondContact O-CA 3.47Å; G139-N166 WeakPolarHBondContact O-CB 3.31Å; G139-N166 PolarHBondContact O-OD1 2.7Å; A161-N166 HydrophobicContact CB-CB 4.34Å; A161-N166 VanDerWaalsContact O-CB 3.25Å; A161-N166 WeakPolarHBondContact O-CB 3.4Å; A161-N166 PolarHBondContact O-N 2.72Å; A161-N166 PolarHBondContact O-ND2 3.06Å; C164-N166 VanDerWaalsContact CB-ND2 3.32Å; C164-N166 WeakPolarHBondContact CB-ND2 3.49Å; N166-Y491 PolarHBondContact ND2-O 3.29Å
167T98.8Very high98.6Very high0 Ų05.1 Ų5.10%03%0.027CC..EExtended strand (participates in β ladder)trans-107.5152.4164.155.10000109A45 A48 G139 V140 C141 V223A45-T167 WeakPolarHBondContact O-CB 3.38Å; A45-T167 WeakPolarHBondContact O-CG2 3.13Å; A45-T167 PolarHBondContact O-OG1 3.3Å; A48-T167 HydrophobicContact CB-CG2 4.06Å; G139-T167 PolarHBondContact O-N 3.27Å; V140-T167 WeakPolarHBondContact CA-O 3.43Å; V140-T167 WeakPolarHBondContact CG2-OG1 3.01Å; C141-T167 PolarHBondContact N-O 3.5Å; T167-V223 CarbonylContact C-O 3.49Å; T167-V223 WeakPolarHBondContact CA-O 3.22Å; T167-V223 HydrophobicContact CG2-CB 4.39Å; T167-V223 HydrophobicContact CG2-CG1 4.47Å; T167-V223 HydrophobicContact CG2-CG2 4.1Å
168V98.9Very high98.6Very high0 Ų06 Ų60%03%0.031CC..EExtended strand (participates in β ladder)trans-127.2143.4-171.5-58.50000112.6C141 V143 I158 A161 V170 V223 V224 N225C141-V168 HydrophobicContact CB-CG1 4.28Å; C141-V168 VanDerWaalsContact O-CA 3.32Å; C141-V168 WeakPolarHBondContact O-CA 3.48Å; V143-V168 HydrophobicContact CG2-CB 4.27Å; V143-V168 HydrophobicContact CG2-CG1 4.23Å; I158-V168 HydrophobicContact CG2-CG2 4.3Å; A161-V168 HydrophobicContact CB-CG1 3.62Å; V168-V170 HydrophobicContact CB-CG2 4.35Å; V168-V170 HydrophobicContact CG2-CG2 4.01Å; V168-V223 PolarHBondContact N-O 3.03Å; V168-V224 HydrophobicContact CG2-CB 4.03Å; V168-V224 HydrophobicContact CG2-CG1 3.83Å; V168-V224 HydrophobicContact CG2-CG2 3.83Å; V168-N225 PolarHBondContact O-N 3.16Å; V168-N225 PolarHBondContact O-ND2 3.01Å; V168-N225 VanDerWaalsContact O-ND2 3.11Å
169V98.9Very high98.6Very high0 Ų05.9 Ų5.90%03%0.031CC..EExtended strand (participates in β ladder)trans-119.7106.1166.5179.90000107A41 V42 A45 V140 C141 G142 V143 N225 V227 V238A41-V169 HydrophobicContact CB-CG1 3.94Å; A41-V169 HydrophobicContact CB-CG2 4.23Å; V42-V169 HydrophobicContact CG2-CG2 3.98Å; A45-V169 HydrophobicContact CB-CG2 3.96Å; V140-V169 HydrophobicContact CG1-CG2 4.2Å; C141-V169 PolarHBondContact O-N 2.98Å; G142-V169 WeakPolarHBondContact CA-O 3.41Å; V143-V169 PolarHBondContact N-O 2.69Å; V169-N225 CarbonylContact C-O 3.51Å; V169-N225 WeakPolarHBondContact CA-O 3.37Å; V169-N225 HydrophobicContact CG2-CB 4.42Å; V169-V227 HydrophobicContact CG1-CG2 3.63Å; V169-V238 HydrophobicContact CG1-CG2 4.3Å
170V98.9Very high98.6Very high0 Ų05.9 Ų5.90%03%0.031CC..EExtended strand (participates in β ladder)trans-97.1125.2-173.3-176.80000110V143 I145 L154 I158 V168 N225 I226 V227V143-V170 HydrophobicContact CB-CB 4.46Å; V143-V170 HydrophobicContact CB-CG2 4.05Å; V143-V170 HydrophobicContact CG1-CG1 4.19Å; V143-V170 HydrophobicContact CG1-CG2 4.12Å; V143-V170 CarbonylContact O-C 3.49Å; V143-V170 VanDerWaalsContact O-CA 3.29Å; V143-V170 WeakPolarHBondContact O-CA 3.37Å; I145-V170 HydrophobicContact CD1-CG1 4.37Å; L154-V170 HydrophobicContact CD1-CG1 3.7Å; L154-V170 HydrophobicContact CD1-CG2 4.16Å; I158-V170 HydrophobicContact CG2-CG2 4.04Å; V168-V170 HydrophobicContact CB-CG2 4.35Å; V168-V170 HydrophobicContact CG2-CG2 4.01Å; V170-N225 PolarHBondContact N-O 3.48Å; V170-I226 HydrophobicContact CB-CG1 4.35Å; V170-I226 CarbonylContact O-C 3.49Å; V170-I226 WeakPolarHBondContact O-CA 3.19Å; V170-V227 WeakPolarHBondContact O-CG2 3.46Å; V170-V227 PolarHBondContact O-N 3.21Å
171K98.7Very high98.6Very high4 Ų46.9 Ų6.92%0.0174%0.036CC..EExtended strand (participates in β ladder)trans-107.6102.3167.6-171-87.7165.6-157.40108.1V143 I144 I145 E174 V227 G229 T234V143-K171 PolarHBondContact O-N 3.48Å; I144-K171 HydrophobicContact CG1-CB 4.29Å; I144-K171 HydrophobicContact CG2-CD 4.22Å; I145-K171 PolarHBondContact N-O 2.75Å; I145-K171 VanDerWaalsContact N-O 3.17Å; K171-E174 IonicContact NZ-OE2 3.13Å; K171-E174 PolarHBondContact NZ-OE2 3.39Å; K171-V227 HydrophobicContact CB-CG2 4.49Å; K171-G229 WeakPolarHBondContact CE-O 3.38Å; K171-G229 PolarHBondContact NZ-O 2.8Å; K171-T234 HydrophobicContact CG-CG2 3.86Å
172P98.8Very high98.5Very high0 Ų08.4 Ų8.40%04%0.043CC..  trans-70157169.731.3-34.9000111.4I145 P177 A180 I226 P228I145-P172 HydrophobicContact CD1-CB 4.12Å; I145-P172 HydrophobicContact CG1-CB 4.21Å; P172-P177 HydrophobicContact CG-CB 4.22Å; P172-A180 HydrophobicContact CB-CB 3.88Å; P172-A180 HydrophobicContact CG-CB 4.19Å; P172-I226 HydrophobicContact CG-CG2 4.14Å; P172-P228 HydrophobicContact CG-CB 3.98Å
173A98.5Very high98.5Very high5 Ų58.5 Ų8.54%0.0414%0.043CC..  trans-59.7139.5172.700000110.6I145 W147 Q175 T176I145-A173 PolarHBondContact O-N 3.32Å; W147-A173 HydrophobicContact CB-CB 3.63Å; W147-A173 HydrophobicContact CG-CB 4.45Å; A173-Q175 PolarHBondContact O-N 3.49Å; A173-T176 CarbonylContact O-C 3.51Å; A173-T176 PolarHBondContact O-N 2.9Å
174E98.1Very high98.5Very high39 Ų398.5 Ų8.518%0.1824%0.043CC..THydrogen-bonded Turntrans-61.9-26.4-179.654.1-90.9-140.200112.4F16 K171 T176 Y230 G231F16-E174 HydrophobicContact CE2-CB 4.18Å; F16-E174 WeakPolarHBondContact CE2-O 3.4Å; K171-E174 IonicContact NZ-OE2 3.13Å; K171-E174 PolarHBondContact NZ-OE2 3.39Å; E174-T176 VanDerWaalsContact C-N 3.32Å; E174-Y230 HydrophobicContact CB-CD1 4.1Å; E174-Y230 HydrophobicContact CB-CE1 4.27Å; E174-Y230 HydrophobicContact CG-CD1 3.76Å; E174-Y230 HydrophobicContact CG-CE1 4.02Å; E174-G231 PolarHBondContact OE1-N 3.15Å
175Q98.3Very high98.4Very high44 Ų449.9 Ų9.921%0.2065%0.053CC..THydrogen-bonded Turntrans-72.1-26.4174.8-61.182.8-4.100112.9W147 A173 I351 D352W147-Q175 HydrophobicContact CB-CB 4.03Å; A173-Q175 PolarHBondContact O-N 3.49Å; Q175-I351 HydrophobicContact CB-CD1 4.08Å; Q175-I351 HydrophobicContact CB-CG1 3.75Å; Q175-I351 HydrophobicContact CG-CG1 4.01Å; Q175-D352 PolarHBondContact NE2-OD2 3.28Å
176T98.5Very high98.4Very high0 Ų09.7 Ų9.70%05%0.051CC..  trans-141.857.1-169.348.50000114.3D88 N89 W147 P150 A173 E174 I351D88-T176 HydrophobicContact CB-CG2 4.37Å; D88-T176 WeakPolarHBondContact OD2-CA 3.49Å; N89-T176 HydrophobicContact CB-CG2 4.09Å; W147-T176 WeakPolarHBondContact CA-OG1 3.41Å; W147-T176 HydrophobicContact CB-CG2 4.13Å; W147-T176 WeakPolarHBondContact CB-OG1 3.21Å; P150-T176 VanDerWaalsContact CG-CB 3.41Å; P150-T176 HydrophobicContact CG-CG2 3.92Å; P150-T176 VanDerWaalsContact CG-OG1 3.27Å; P150-T176 WeakPolarHBondContact CG-OG1 3.17Å; A173-T176 CarbonylContact O-C 3.51Å; A173-T176 PolarHBondContact O-N 2.9Å; E174-T176 VanDerWaalsContact C-N 3.32Å; T176-I351 HydrophobicContact CG2-CD1 3.74Å
177P98.6Very high98.3Very high0 Ų09.7 Ų9.70%05%0.051CC..  trans-78.6-16.9-176.433.6-37000114F16 V30 P172 A180 L181 P228F16-P177 HydrophobicContact CE2-CG 4.22Å; F16-P177 HydrophobicContact CZ-CB 4.46Å; F16-P177 HydrophobicContact CZ-CG 4.2Å; V30-P177 HydrophobicContact CB-CG 4.42Å; V30-P177 HydrophobicContact CG1-CB 4.42Å; V30-P177 HydrophobicContact CG1-CG 4.4Å; V30-P177 HydrophobicContact CG2-CG 3.87Å; P172-P177 HydrophobicContact CG-CB 4.22Å; P177-A180 PolarHBondContact O-N 2.93Å; P177-L181 HydrophobicContact CB-CD1 4.25Å; P177-L181 WeakPolarHBondContact O-CG 3.25Å; P177-L181 PolarHBondContact O-N 3.11Å; P177-L181 VanDerWaalsContact O-N 3.16Å; P177-P228 HydrophobicContact CB-CB 3.99Å
178L98.7Very high98Very high18 Ų1810.5 Ų10.59%0.0946%0.058CC..Hα-helixtrans-70.5-44.3-156.7-61.3-177.6000113.7T18 I27 V30 L84 D88 A180 L181 H182T18-L178 HydrophobicContact CG2-CD1 4.15Å; T18-L178 HydrophobicContact CG2-CD2 4.01Å; T18-L178 HydrophobicContact CG2-CG 4.21Å; I27-L178 HydrophobicContact CD1-CD1 4.47Å; I27-L178 HydrophobicContact CG2-CD1 4.05Å; V30-L178 HydrophobicContact CG2-CD2 4.08Å; L84-L178 HydrophobicContact CD1-CB 3.72Å; L84-L178 HydrophobicContact CD1-CD1 3.64Å; L84-L178 HydrophobicContact CD1-CG 4.31Å; L84-L178 HydrophobicContact CD2-CB 3.85Å; L84-L178 HydrophobicContact CG-CB 3.66Å; L84-L178 HydrophobicContact CG-CD1 4.43Å; D88-L178 HydrophobicContact CB-CD1 4.14Å; D88-L178 HydrophobicContact CB-CG 4.45Å; D88-L178 WeakPolarHBondContact OD1-CD1 3.49Å; D88-L178 VanDerWaalsContact OD2-CB 3.25Å; D88-L178 WeakPolarHBondContact OD2-CB 3.28Å; D88-L178 WeakPolarHBondContact OD2-CG 3.36Å; D88-L178 PolarHBondContact OD2-N 3.24Å; L178-A180 PolarHBondContact O-N 2.68Å; L178-L181 PolarHBondContact O-N 2.97Å; L178-H182 PolarHBondContact O-N 3.29Å
179T98.6Very high97.7Very high0 Ų013.4 Ų13.40%07%0.071CC..Hα-helixtrans-68.5-35.4-180500000112.5L81 L84 E85 L181 H182 V183L81-T179 HydrophobicContact CD2-CG2 4.46Å; L84-T179 HydrophobicContact CB-CG2 3.9Å; L84-T179 HydrophobicContact CD2-CG2 4.08Å; L84-T179 HydrophobicContact CG-CG2 3.94Å; E85-T179 HydrophobicContact CB-CG2 3.9Å; E85-T179 VanDerWaalsContact OE2-CB 3.28Å; E85-T179 WeakPolarHBondContact OE2-CB 3.29Å; E85-T179 WeakPolarHBondContact OE2-CG2 3.39Å; E85-T179 PolarHBondContact OE2-OG1 2.64Å; T179-L181 VanDerWaalsContact C-N 3.34Å; T179-L181 PolarHBondContact O-N 2.64Å; T179-H182 PolarHBondContact O-N 3.05Å; T179-V183 WeakPolarHBondContact O-CG2 3.32Å; T179-V183 PolarHBondContact O-N 3Å
180A98.7Very high97.3Very high0 Ų013.4 Ų13.40%07%0.071CC..Hα-helixtrans-62.1-42.5173.100000111.7L154 P172 P177 L178 V183 G184 I226L154-A180 HydrophobicContact CD2-CB 4.1Å; P172-A180 HydrophobicContact CB-CB 3.88Å; P172-A180 HydrophobicContact CG-CB 4.19Å; P177-A180 PolarHBondContact O-N 2.93Å; L178-A180 PolarHBondContact O-N 2.68Å; A180-V183 PolarHBondContact O-N 2.97Å; A180-G184 PolarHBondContact O-N 3.33Å; A180-I226 HydrophobicContact CB-CG2 4.39Å; A180-I226 WeakPolarHBondContact O-CD1 3.43Å
181L98.5Very high96.4Very high22 Ų2214.1 Ų14.112%0.1158%0.077CC..Hα-helixtrans-64-43.1175.5-64.6168.8000111.4W7 V30 P177 L178 T179 V183 G184 S185 I226 P228W7-L181 HydrophobicContact CH2-CB 4.17Å; W7-L181 HydrophobicContact CH2-CD2 4.49Å; W7-L181 WeakPolarHBondContact CH2-O 3.49Å; W7-L181 HydrophobicContact CZ3-CB 4.41Å; W7-L181 HydrophobicContact CZ3-CD2 4.01Å; V30-L181 HydrophobicContact CG1-CD1 3.81Å; V30-L181 HydrophobicContact CG2-CD1 4.42Å; P177-L181 HydrophobicContact CB-CD1 4.25Å; P177-L181 WeakPolarHBondContact O-CG 3.25Å; P177-L181 PolarHBondContact O-N 3.11Å; P177-L181 VanDerWaalsContact O-N 3.16Å; L178-L181 PolarHBondContact O-N 2.97Å; T179-L181 VanDerWaalsContact C-N 3.34Å; T179-L181 PolarHBondContact O-N 2.64Å; L181-V183 VanDerWaalsContact C-N 3.32Å; L181-V183 PolarHBondContact O-N 2.86Å; L181-G184 WeakPolarHBondContact O-CA 3.31Å; L181-G184 PolarHBondContact O-N 3.34Å; L181-S185 PolarHBondContact O-N 2.89Å; L181-I226 HydrophobicContact CD2-CG2 4.13Å; L181-P228 HydrophobicContact CD2-CG 4.09Å
182H98.4Very high95.1Very high32 Ų3220 Ų2015%0.14810%0.104CC..Hα-helixtrans-60.3-42.3175.3-166.462.6000111.9D77 Y80 L81 L84 L178 T179 G184 S185 L186D77-H182 IonicContact OD2-CD2 2.97Å; D77-H182 IonicContact OD2-CE1 2.66Å; D77-H182 IonicContact OD2-NE2 3.33Å; D77-H182 PolarHBondContact OD2-NE2 3.05Å; Y80-H182 AromaticContact CD1-CD2 3.76Å; Y80-H182 AromaticContact CD1-CE1 3.67Å; Y80-H182 AromaticContact CD1-CG 3.99Å; Y80-H182 AromaticContact CD1-ND1 3.96Å; Y80-H182 AromaticContact CD1-NE2 3.54Å; Y80-H182 HydrophobicContact CE1-CB 4.49Å; Y80-H182 AromaticContact CE1-CD2 3.95Å; Y80-H182 AromaticContact CE1-CE1 3.5Å; Y80-H182 VanDerWaalsContact CE1-CE1 3.5Å; Y80-H182 WeakPolarHBondContact CE1-CE1 3.22Å; Y80-H182 AromaticContact CE1-CG 3.69Å; Y80-H182 AromaticContact CE1-ND1 3.41Å; Y80-H182 WeakPolarHBondContact CE1-ND1 3.42Å; Y80-H182 AromaticContact CE1-NE2 3.82Å; L81-H182 HydrophobicContact CD2-CB 4.22Å; L84-H182 HydrophobicContact CD2-CB 4.06Å; L178-H182 PolarHBondContact O-N 3.29Å; T179-H182 PolarHBondContact O-N 3.05Å; H182-G184 VanDerWaalsContact C-N 3.25Å; H182-G184 PolarHBondContact O-N 3Å; H182-S185 WeakPolarHBondContact O-CA 3.06Å; H182-S185 VanDerWaalsContact O-CB 3.31Å; H182-S185 WeakPolarHBondContact O-CB 3.17Å; H182-S185 PolarHBondContact O-N 3.22Å; H182-S185 PolarHBondContact O-OG 2.82Å; H182-L186 PolarHBondContact O-N 3.13Å; H182-L186 VanDerWaalsContact O-N 3.11Å
183V98.3Very high93.1Very high2 Ų225.4 Ų25.41%0.01213%0.128CC..Hα-helixtrans-60.4-35.1173.5171.20000111.8L70 M74 L81 L151 L154 T179 A180 L181 S185 L186 I187L70-V183 HydrophobicContact CD1-CG1 4.4Å; M74-V183 HydrophobicContact SD-CG2 4.36Å; L81-V183 HydrophobicContact CD2-CG2 4.3Å; L151-V183 HydrophobicContact CD1-CG2 3.52Å; L154-V183 HydrophobicContact CD2-CB 3.82Å; L154-V183 HydrophobicContact CD2-CG1 3.78Å; L154-V183 HydrophobicContact CD2-CG2 4.02Å; T179-V183 WeakPolarHBondContact O-CG2 3.32Å; T179-V183 PolarHBondContact O-N 3Å; A180-V183 PolarHBondContact O-N 2.97Å; L181-V183 VanDerWaalsContact C-N 3.32Å; L181-V183 PolarHBondContact O-N 2.86Å; V183-S185 VanDerWaalsContact C-N 3.3Å; V183-S185 PolarHBondContact O-N 2.71Å; V183-L186 PolarHBondContact O-N 2.86Å; V183-L186 VanDerWaalsContact O-N 3.14Å; V183-I187 HydrophobicContact CG1-CD1 3.96Å; V183-I187 HydrophobicContact CG1-CG1 4.4Å; V183-I187 WeakPolarHBondContact O-CG1 3.27Å; V183-I187 PolarHBondContact O-N 2.99Å
184G97.6Very high90.9Very high0 Ų026.5 Ų26.50%013%0.133CC..Hα-helixtrans-55.7-42.8169.700000112.7F2 A180 L181 H182 L186 I187 A188F2-G184 WeakPolarHBondContact CE2-O 3.43Å; F2-G184 WeakPolarHBondContact CZ-O 3.36Å; A180-G184 PolarHBondContact O-N 3.33Å; L181-G184 WeakPolarHBondContact O-CA 3.31Å; L181-G184 PolarHBondContact O-N 3.34Å; H182-G184 VanDerWaalsContact C-N 3.25Å; H182-G184 PolarHBondContact O-N 3Å; G184-L186 PolarHBondContact O-N 3.45Å; G184-I187 PolarHBondContact O-N 2.93Å; G184-A188 PolarHBondContact O-N 3.3Å; G184-A188 VanDerWaalsContact O-N 3.12Å
185S96.6Very high88.5Confident36 Ų3627.9 Ų27.925%0.25215%0.147SC..Hα-helixtrans-63-40.4174.684.90000112.4L181 H182 V183 I187 A188 E189L181-S185 PolarHBondContact O-N 2.89Å; H182-S185 WeakPolarHBondContact O-CA 3.06Å; H182-S185 VanDerWaalsContact O-CB 3.31Å; H182-S185 WeakPolarHBondContact O-CB 3.17Å; H182-S185 PolarHBondContact O-N 3.22Å; H182-S185 PolarHBondContact O-OG 2.82Å; V183-S185 VanDerWaalsContact C-N 3.3Å; V183-S185 PolarHBondContact O-N 2.71Å; S185-I187 VanDerWaalsContact C-N 3.33Å; S185-I187 PolarHBondContact O-N 3.31Å; S185-A188 PolarHBondContact O-N 2.91Å; S185-E189 PolarHBondContact O-N 2.99Å
186L97Very high86Confident1 Ų131.9 Ų31.91%0.00517%0.165CC..Hα-helixtrans-68.6-32.5178.2-58.2-176.6000112L70 L73 M74 D77 L81 H182 V183 G184 E189 A190L70-L186 HydrophobicContact CD1-CB 3.88Å; L73-L186 HydrophobicContact CB-CB 4.3Å; L73-L186 HydrophobicContact CB-CD1 4.41Å; L73-L186 HydrophobicContact CB-CD2 4.35Å; L73-L186 HydrophobicContact CD1-CB 4.5Å; L73-L186 VanDerWaalsContact CD1-O 3.31Å; L73-L186 WeakPolarHBondContact CD1-O 3.23Å; M74-L186 HydrophobicContact CG-CD1 3.82Å; D77-L186 WeakPolarHBondContact OD2-CD2 3.4Å; L81-L186 HydrophobicContact CD1-CD1 4.21Å; H182-L186 PolarHBondContact O-N 3.13Å; H182-L186 VanDerWaalsContact O-N 3.11Å; V183-L186 PolarHBondContact O-N 2.86Å; V183-L186 VanDerWaalsContact O-N 3.14Å; G184-L186 PolarHBondContact O-N 3.45Å; L186-E189 PolarHBondContact O-N 3.16Å; L186-A190 VanDerWaalsContact O-CB 3.29Å; L186-A190 WeakPolarHBondContact O-CB 3.49Å; L186-A190 PolarHBondContact O-N 3.35Å
187I95.9Very high83.7Confident1 Ų135.7 Ų35.71%0.00519%0.185CC..Hα-helixtrans-65.8-42.4173.2-71.3163.6000110.6L70 V183 G184 S185 A190 S191 F219 V224L70-I187 HydrophobicContact CD1-CG1 3.77Å; L70-I187 HydrophobicContact CD2-CD1 4.36Å; L70-I187 HydrophobicContact CD2-CG1 3.93Å; L70-I187 HydrophobicContact CG-CG1 4.49Å; V183-I187 HydrophobicContact CG1-CD1 3.96Å; V183-I187 HydrophobicContact CG1-CG1 4.4Å; V183-I187 WeakPolarHBondContact O-CG1 3.27Å; V183-I187 PolarHBondContact O-N 2.99Å; G184-I187 PolarHBondContact O-N 2.93Å; S185-I187 VanDerWaalsContact C-N 3.33Å; S185-I187 PolarHBondContact O-N 3.31Å; I187-A190 WeakPolarHBondContact O-CB 3.15Å; I187-A190 PolarHBondContact O-N 2.72Å; I187-S191 PolarHBondContact O-N 3Å; I187-S191 PolarHBondContact O-OG 3.46Å; I187-F219 HydrophobicContact CG2-CB 3.97Å; I187-F219 HydrophobicContact CG2-CD2 3.99Å; I187-F219 HydrophobicContact CG2-CG 3.94Å; I187-V224 HydrophobicContact CD1-CB 4.05Å; I187-V224 HydrophobicContact CD1-CG1 3.72Å; I187-V224 HydrophobicContact CD1-CG2 4.03Å; I187-V224 HydrophobicContact CG2-CB 4.32Å; I187-V224 HydrophobicContact CG2-CG2 4.36Å
188A93.2Very high81.2Confident17 Ų1737.3 Ų37.314%0.1419%0.193CC..Hα-helixtrans-63.8-40.8173.600000111.8F2 G184 S185 S191F2-A188 HydrophobicContact CE2-CB 3.94Å; F2-A188 HydrophobicContact CZ-CB 3.99Å; G184-A188 PolarHBondContact O-N 3.3Å; G184-A188 VanDerWaalsContact O-N 3.12Å; S185-A188 PolarHBondContact O-N 2.91Å; A188-S191 VanDerWaalsContact O-CB 3.28Å; A188-S191 WeakPolarHBondContact O-CB 3.3Å; A188-S191 PolarHBondContact O-N 3.49Å
189E93.3Very high78.8Confident60 Ų6039.9 Ų39.928%0.2821%0.212SC..Hα-helixtrans-64.9-40.7175.6-164.7-167.3145.900111.9R69 L73 R76 S185 L186 S191 Q192R69-E189 PolarHBondContact NH2-O 3.18Å; L73-E189 HydrophobicContact CD1-CB 4.21Å; L73-E189 WeakPolarHBondContact CD2-OE1 3.34Å; R76-E189 IonicContact CZ-OE1 3.92Å; R76-E189 IonicContact CZ-OE2 2.59Å; R76-E189 IonicContact NH1-OE1 3.15Å; R76-E189 PolarHBondContact NH1-OE1 2.91Å; R76-E189 IonicContact NH1-OE2 3.81Å; R76-E189 PolarHBondContact NH1-OE2 3.22Å; R76-E189 IonicContact NH2-OE1 3.77Å; R76-E189 IonicContact NH2-OE2 2.78Å; R76-E189 PolarHBondContact NH2-OE2 2.78Å; S185-E189 PolarHBondContact O-N 2.99Å; L186-E189 PolarHBondContact O-N 3.16Å; E189-S191 PolarHBondContact O-N 3.32Å; E189-Q192 PolarHBondContact O-N 3.09Å
190A90.2Very high76.5Confident0 Ų044.2 Ų44.20%024%0.239CC..Hα-helixtrans-55.7-21.517200000111.9R69 L73 L186 I187 F219R69-A190 HydrophobicContact CG-CB 4.47Å; R69-A190 PolarHBondContact NH1-O 3.45Å; R69-A190 VanDerWaalsContact NH2-CA 3.31Å; R69-A190 PolarHBondContact NH2-O 3.46Å; L73-A190 HydrophobicContact CD1-CB 3.88Å; L186-A190 VanDerWaalsContact O-CB 3.29Å; L186-A190 WeakPolarHBondContact O-CB 3.49Å; L186-A190 PolarHBondContact O-N 3.35Å; I187-A190 WeakPolarHBondContact O-CB 3.15Å; I187-A190 PolarHBondContact O-N 2.72Å; A190-F219 HydrophobicContact CB-CD2 3.91Å; A190-F219 HydrophobicContact CB-CE2 4.07Å
191S80Confident74.1Confident16 Ų1649.4 Ų49.411%0.11226%0.263CS..Hα-helixtrans-83.4-21.6174.8-63.10000115.3I187 A188 E189 S218 F219I187-S191 PolarHBondContact O-N 3Å; I187-S191 PolarHBondContact O-OG 3.46Å; A188-S191 VanDerWaalsContact O-CB 3.28Å; A188-S191 WeakPolarHBondContact O-CB 3.3Å; A188-S191 PolarHBondContact O-N 3.49Å; E189-S191 PolarHBondContact O-N 3.32Å; S191-S218 WeakPolarHBondContact O-CB 3.33Å; S191-F219 WeakPolarHBondContact OG-CA 3.42Å; S191-F219 WeakPolarHBondContact OG-CB 3.34Å; S191-F219 PolarHBondContact OG-N 3.49Å; S191-F219 PolarHBondContact OG-O 2.93Å
192Q71.9Confident71.8Confident127 Ų12756.5 Ų56.559%0.59329%0.293SS*.Hα-helixtrans-92.7-33-167.5-67.3177.71.700115.7E189 I194 S195E189-Q192 PolarHBondContact O-N 3.09Å; Q192-I194 PolarHBondContact O-N 3.04Å; Q192-S195 WeakPolarHBondContact O-CB 3.45Å; Q192-S195 PolarHBondContact O-N 3.44Å
193F56Low69.8Low113 Ų11360.5 Ų60.550%0.49632%0.32SS..Hα-helixtrans-68.6-33-167.1-174.4-105000114.8S195 Q196 I197F193-S195 VanDerWaalsContact C-N 3.27Å; F193-S195 PolarHBondContact O-N 3.32Å; F193-Q196 PolarHBondContact O-N 3.42Å; F193-Q196 VanDerWaalsContact O-N 3.17Å; F193-I197 HydrophobicContact CD1-CD1 4.08Å; F193-I197 HydrophobicContact CE1-CD1 3.76Å
194I52.9Low67.7Low29 Ų2965.5 Ų65.515%0.14935%0.35CS..Hα-helixtrans-75.7-22.7-177.2-47.8-177.1000111.1L65 Q192 Q196 I197 I198 S216 A217L65-I194 HydrophobicContact CD2-CD1 4.49Å; Q192-I194 PolarHBondContact O-N 3.04Å; I194-Q196 PolarHBondContact O-N 3.06Å; I194-I197 PolarHBondContact O-N 3.28Å; I194-I198 HydrophobicContact CG2-CD1 4.29Å; I194-I198 HydrophobicContact CG2-CG1 4.46Å; I194-I198 WeakPolarHBondContact O-CG1 3.37Å; I194-I198 PolarHBondContact O-N 2.75Å; I194-S216 VanDerWaalsContact CB-CB 3.43Å; I194-S216 VanDerWaalsContact CG2-CA 3.44Å; I194-S216 VanDerWaalsContact CG2-CB 3.44Å; I194-A217 HydrophobicContact CD1-CB 4.16Å; I194-A217 VanDerWaalsContact CD1-O 3.29Å; I194-A217 WeakPolarHBondContact CD1-O 3.02Å
195S47.3Very low65.3Low67 Ų6770 Ų7047%0.46938%0.378SS..Hα-helixtrans-59.8-30.6170.4-49.60000112.1Q192 F193 S199Q192-S195 WeakPolarHBondContact O-CB 3.45Å; Q192-S195 PolarHBondContact O-N 3.44Å; F193-S195 VanDerWaalsContact C-N 3.27Å; F193-S195 PolarHBondContact O-N 3.32Å; S195-S199 PolarHBondContact O-N 2.97Å
196Q46.4Very low62.9Low128 Ų12878.8 Ų78.860%0.59841%0.412SS*.Hα-helixtrans-78.1-40.6179.5-66.3-176.9-8.900112.7F193 I194 I198 S199 V200F193-Q196 PolarHBondContact O-N 3.42Å; F193-Q196 VanDerWaalsContact O-N 3.17Å; I194-Q196 PolarHBondContact O-N 3.06Å; Q196-I198 VanDerWaalsContact C-N 3.33Å; Q196-I198 PolarHBondContact O-N 2.91Å; Q196-S199 PolarHBondContact O-N 3.05Å; Q196-S199 VanDerWaalsContact O-N 3.15Å; Q196-S199 PolarHBondContact O-OG 2.84Å; Q196-V200 PolarHBondContact O-N 3.38Å
197I49.1Very low60.5Low80 Ų8084.5 Ų84.541%0.4144%0.441SS..Hα-helixtrans-61.7-42178.2-64.7177.4000110.9F193 I194 S199 V200 E201F193-I197 HydrophobicContact CD1-CD1 4.08Å; F193-I197 HydrophobicContact CE1-CD1 3.76Å; I194-I197 PolarHBondContact O-N 3.28Å; I197-S199 VanDerWaalsContact C-N 3.27Å; I197-S199 PolarHBondContact O-N 2.71Å; I197-V200 PolarHBondContact O-N 2.87Å; I197-E201 PolarHBondContact O-N 2.91Å
198I47.6Very low57.8Low35 Ų3594.1 Ų94.118%0.17949%0.486CS..Hα-helixtrans-65.5-31.6178.2-63.3170.3000111.7I194 Q196 V200 K202 F214I194-I198 HydrophobicContact CG2-CD1 4.29Å; I194-I198 HydrophobicContact CG2-CG1 4.46Å; I194-I198 WeakPolarHBondContact O-CG1 3.37Å; I194-I198 PolarHBondContact O-N 2.75Å; Q196-I198 VanDerWaalsContact C-N 3.33Å; Q196-I198 PolarHBondContact O-N 2.91Å; I198-V200 VanDerWaalsContact C-N 3.3Å; I198-V200 PolarHBondContact O-N 2.9Å; I198-K202 HydrophobicContact CG2-CD 4.24Å; I198-K202 HydrophobicContact CG2-CG 4.5Å; I198-K202 WeakPolarHBondContact O-CG 3.24Å; I198-K202 PolarHBondContact O-N 2.78Å; I198-F214 WeakPolarHBondContact CD1-O 3.28Å
199S46.9Very low55.1Low71 Ų71100.6 Ų100.650%0.49751%0.513SS..Hα-helixtrans-66.9-32.617883.20000112.5S195 Q196 I197S195-S199 PolarHBondContact O-N 2.97Å; Q196-S199 PolarHBondContact O-N 3.05Å; Q196-S199 VanDerWaalsContact O-N 3.15Å; Q196-S199 PolarHBondContact O-OG 2.84Å; I197-S199 VanDerWaalsContact C-N 3.27Å; I197-S199 PolarHBondContact O-N 2.71Å
200V50.3Low52.5Low91 Ų91103 Ų10355%0.55253%0.534SS*.Hα-helixtrans-76.2-42.4179.3179.60000110.9Q196 I197 I198 K202 T203 T204Q196-V200 PolarHBondContact O-N 3.38Å; I197-V200 PolarHBondContact O-N 2.87Å; I198-V200 VanDerWaalsContact C-N 3.3Å; I198-V200 PolarHBondContact O-N 2.9Å; V200-K202 VanDerWaalsContact C-N 3.35Å; V200-K202 PolarHBondContact O-N 3Å; V200-T203 PolarHBondContact O-N 3.42Å; V200-T203 PolarHBondContact O-OG1 3.36Å; V200-T204 PolarHBondContact O-OG1 2.59Å
201E49.4Very low49.9Very low110 Ų110110.4 Ų110.451%0.51457%0.574SS.*Hα-helixtrans-65.7-36.7179.3-75.9-173.2154.700112.7I197 T203 T204 T205I197-E201 PolarHBondContact O-N 2.91Å; E201-T203 PolarHBondContact O-N 3.44Å; E201-T203 VanDerWaalsContact O-N 3.14Å; E201-T204 PolarHBondContact O-N 3.35Å; E201-T204 VanDerWaalsContact O-N 3.1Å; E201-T204 PolarHBondContact O-OG1 2.81Å; E201-T205 PolarHBondContact O-OG1 2.85Å
202K50.5Low47.8Very low170 Ų170117.9 Ų117.974%0.73960%0.604SS**THydrogen-bonded Turntrans-62.5-20177.2-76.8-177.4178.8-1790113.8I198 V200I198-K202 HydrophobicContact CG2-CD 4.24Å; I198-K202 HydrophobicContact CG2-CG 4.5Å; I198-K202 WeakPolarHBondContact O-CG 3.24Å; I198-K202 PolarHBondContact O-N 2.78Å; V200-K202 VanDerWaalsContact C-N 3.35Å; V200-K202 PolarHBondContact O-N 3Å
203T54.6Low46.2Very low116 Ų116118.4 Ų118.471%0.71261%0.607SS**THydrogen-bonded Turntrans-86.2-11.9176.236.70000114.8V200 E201V200-T203 PolarHBondContact O-N 3.42Å; V200-T203 PolarHBondContact O-OG1 3.36Å; E201-T203 PolarHBondContact O-N 3.44Å; E201-T203 VanDerWaalsContact O-N 3.14Å
204T54.4Low45.6Very low107 Ų107118.9 Ų118.966%0.65661%0.609SS**THydrogen-bonded Turntrans-119.7-7.6-166.932.10000117V200 E201V200-T204 PolarHBondContact O-OG1 2.59Å; E201-T204 PolarHBondContact O-N 3.35Å; E201-T204 VanDerWaalsContact O-N 3.1Å; E201-T204 PolarHBondContact O-OG1 2.81Å
205T47.2Very low45.4Very low94 Ų94121.9 Ų121.958%0.57763%0.625SS**  trans-139.2107.5-177.5390000113.6E201 I207E201-T205 PolarHBondContact O-OG1 2.85Å; T205-I207 PolarHBondContact O-N 2.91Å
206K46Very low45.7Very low221 Ų221120.2 Ų120.296%0.96161%0.614SS**  trans-82.358162.7-76.5-172.9175.6-178.80110.9
207I48.5Very low46.4Very low121 Ų121114.2 Ų114.262%0.62159%0.586SS**  trans-120.8110.6173.7-56.5179.3000107.6T205 Q209T205-I207 PolarHBondContact O-N 2.91Å; I207-Q209 VanDerWaalsContact C-N 3.25Å; I207-Q209 HydrophobicContact CG2-CG 3.82Å; I207-Q209 PolarHBondContact O-N 3.48Å
208E39Very low48Very low203 Ų203111.6 Ų111.695%0.94958%0.575SS**  trans-65.486.7166.8-71.3-178.8164.100108.6
209Q36.2Very low50.1Low153 Ų153110 Ų11072%0.71557%0.566SS**  trans-90.2144.5161.3-70.5-144.9-12.500108.9I207 N211I207-Q209 VanDerWaalsContact C-N 3.25Å; I207-Q209 HydrophobicContact CG2-CG 3.82Å; I207-Q209 PolarHBondContact O-N 3.48Å; Q209-N211 PolarHBondContact O-N 3.46Å
210P38.7Very low52.3Low110 Ų110107 Ų10771%0.71455%0.545SS*.  trans-54.4131.5179.924.3-33000108.7F212P210-F212 PolarHBondContact O-N 2.9Å
211N34.4Very low54.5Low156 Ų156106 Ų10683%0.83454%0.541SS*.  trans-40.567.6-174.7-68.7-27.7000115.8Q209 Q213Q209-N211 PolarHBondContact O-N 3.46Å; N211-Q213 PolarHBondContact O-N 3.35Å
212F37.3Very low56.7Low173 Ų173100.8 Ų100.876%0.75952%0.516SS*.  trans-76.676.2149.6-87-82.8000105P210 F214P210-F212 PolarHBondContact O-N 2.9Å; F212-F214 HydrophobicContact CB-CE2 4.33Å; F212-F214 WeakPolarHBondContact O-CD2 3.19Å; F212-F214 PolarHBondContact O-N 3.18Å
213Q37.4Very low59Low138 Ų13892.7 Ų92.765%0.64548%0.481SS*.  trans-62.397.7162.1-145.4173.5-37.800104.1N211 D215N211-Q213 PolarHBondContact O-N 3.35Å; Q213-D215 WeakPolarHBondContact CG-OD1 3.36Å; Q213-D215 PolarHBondContact NE2-OD1 3.31Å; Q213-D215 PolarHBondContact O-N 2.87Å
214F42.9Very low61.1Low124 Ų12487.2 Ų87.254%0.54445%0.448SS..  trans-63.968.6160.5-73.3-89.9000105.8I198 F212 S216I198-F214 WeakPolarHBondContact CD1-O 3.28Å; F212-F214 HydrophobicContact CB-CE2 4.33Å; F212-F214 WeakPolarHBondContact O-CD2 3.19Å; F212-F214 PolarHBondContact O-N 3.18Å; F214-S216 PolarHBondContact O-N 2.87Å
215D49Very low63.2Low91 Ų9182.1 Ų82.149%0.48742%0.417SS..  trans-58.5118.2175-94.1-17.1000105.3Q213 A217Q213-D215 WeakPolarHBondContact CG-OD1 3.36Å; Q213-D215 PolarHBondContact NE2-OD1 3.31Å; Q213-D215 PolarHBondContact O-N 2.87Å; D215-A217 PolarHBondContact O-N 2.86Å
216S54.6Low65.6Low32 Ų3277.8 Ų77.822%0.22439%0.39CS..  trans-47109.3179.139.50000108.6I194 F214 S218I194-S216 VanDerWaalsContact CB-CB 3.43Å; I194-S216 VanDerWaalsContact CG2-CA 3.44Å; I194-S216 VanDerWaalsContact CG2-CB 3.44Å; F214-S216 PolarHBondContact O-N 2.87Å; S216-S218 PolarHBondContact O-N 3.38Å
217A60.5Low68.2Low2 Ų267.2 Ų67.22%0.01734%0.344CS..  trans-62.6109.9171.500000107.4R62 L65 L66 I194 D215R62-A217 HydrophobicContact CB-CB 4.16Å; L65-A217 HydrophobicContact CD2-CB 4.37Å; L66-A217 HydrophobicContact CD1-CB 4.36Å; L66-A217 HydrophobicContact CD2-CB 4.27Å; L66-A217 VanDerWaalsContact CD2-O 3.29Å; L66-A217 WeakPolarHBondContact CD2-O 3.22Å; L66-A217 HydrophobicContact CG-CB 4.04Å; I194-A217 HydrophobicContact CD1-CB 4.16Å; I194-A217 VanDerWaalsContact CD1-O 3.29Å; I194-A217 WeakPolarHBondContact CD1-O 3.02Å; D215-A217 PolarHBondContact O-N 2.86Å
218S83Confident70.5Confident25 Ų2561.5 Ų61.518%0.17531%0.314CS..  trans-122.3150.4172.759.20000108.2L66 S191 S216 P220L66-S218 WeakPolarHBondContact CD1-O 3.45Å; S191-S218 WeakPolarHBondContact O-CB 3.33Å; S216-S218 PolarHBondContact O-N 3.38Å; S218-P220 WeakPolarHBondContact O-CD 3.44Å; S218-P220 VanDerWaalsContact O-N 3.16Å
219F91.6Very high73.4Confident1 Ų151.8 Ų51.80%0.00427%0.269CS..  trans-66.8110.5162.9-76.6-79.4000108.1N5 W55 L66 L70 L162 I187 A190 S191 V223N5-F219 PolarHBondContact ND2-O 3.05Å; N5-F219 VanDerWaalsContact ND2-O 3.09Å; W55-F219 HydrophobicContact CH2-CD1 4.19Å; W55-F219 HydrophobicContact CH2-CE1 4.02Å; W55-F219 HydrophobicContact CZ3-CD1 4.26Å; W55-F219 HydrophobicContact CZ3-CE1 4.47Å; L66-F219 HydrophobicContact CB-CD2 4.27Å; L66-F219 HydrophobicContact CB-CE1 4.18Å; L66-F219 HydrophobicContact CB-CE2 3.72Å; L66-F219 HydrophobicContact CB-CZ 3.68Å; L66-F219 HydrophobicContact CD1-CD1 4.46Å; L66-F219 HydrophobicContact CD1-CG 4.46Å; L66-F219 HydrophobicContact CD2-CD2 3.97Å; L66-F219 HydrophobicContact CD2-CE2 4.15Å; L66-F219 HydrophobicContact CG-CE2 4.45Å; L70-F219 HydrophobicContact CB-CE2 4.47Å; L162-F219 HydrophobicContact CD1-CE1 3.89Å; L162-F219 HydrophobicContact CD1-CZ 4.35Å; L162-F219 HydrophobicContact CD2-CE1 4.37Å; I187-F219 HydrophobicContact CG2-CB 3.97Å; I187-F219 HydrophobicContact CG2-CD2 3.99Å; I187-F219 HydrophobicContact CG2-CG 3.94Å; A190-F219 HydrophobicContact CB-CD2 3.91Å; A190-F219 HydrophobicContact CB-CE2 4.07Å; S191-F219 WeakPolarHBondContact OG-CA 3.42Å; S191-F219 WeakPolarHBondContact OG-CB 3.34Å; S191-F219 PolarHBondContact OG-N 3.49Å; S191-F219 PolarHBondContact OG-O 2.93Å; F219-V223 HydrophobicContact CD1-CG1 4.17Å
220P93.3Very high76.3Confident8 Ų848.8 Ų48.85%0.05225%0.252CS..  trans-59.5146.2177.9-20.734.4000110.3L54 W55 S218 G222 V223L54-P220 HydrophobicContact CB-CB 4.45Å; L54-P220 HydrophobicContact CB-CG 4.11Å; L54-P220 HydrophobicContact CD2-CB 4.17Å; L54-P220 HydrophobicContact CD2-CG 3.81Å; L54-P220 HydrophobicContact CG-CG 3.9Å; W55-P220 HydrophobicContact CB-CG 4.13Å; W55-P220 HydrophobicContact CE3-CG 4.23Å; S218-P220 WeakPolarHBondContact O-CD 3.44Å; S218-P220 VanDerWaalsContact O-N 3.16Å; P220-G222 PolarHBondContact O-N 2.87Å; P220-V223 HydrophobicContact CB-CG2 4.05Å; P220-V223 HydrophobicContact CG-CG2 4.14Å; P220-V223 WeakPolarHBondContact O-CB 3.49Å; P220-V223 WeakPolarHBondContact O-CG2 3.17Å; P220-V223 PolarHBondContact O-N 3.24Å; P220-V223 VanDerWaalsContact O-N 3.17Å
221P95.1Very high79.2Confident71 Ų7144.9 Ų44.946%0.46123%0.231SC..THydrogen-bonded Turntrans-47.8134.5171.7-28.736.6000111.5D4 N5 A48 V223D4-P221 WeakPolarHBondContact OD1-CA 3.44Å; D4-P221 WeakPolarHBondContact OD1-CB 3.46Å; N5-P221 HydrophobicContact CB-CB 4.5Å; A48-P221 VanDerWaalsContact CB-O 3.28Å; A48-P221 WeakPolarHBondContact CB-O 3.23Å; P221-V223 VanDerWaalsContact C-N 3.34Å; P221-V223 PolarHBondContact O-N 3.19Å
222G97.1Very high82.2Confident0 Ų042.1 Ų42.10%022%0.222CC..THydrogen-bonded Turntrans87.6-7.9177.200000114.6D4 A45 P220 V224 N225D4-G222 PolarHBondContact OD1-N 3.44Å; A45-G222 VanDerWaalsContact CA-O 3.24Å; A45-G222 WeakPolarHBondContact CA-O 3Å; P220-G222 PolarHBondContact O-N 2.87Å; G222-V224 VanDerWaalsContact C-N 3.34Å; G222-V224 PolarHBondContact O-N 3.41Å; G222-N225 PolarHBondContact O-ND2 3.33Å
223V98Very high85.1Confident0 Ų037.4 Ų37.40%020%0.204CC..SBendtrans-65.6-37.8176.9170.30000112.3A48 W55 L162 T167 V168 F219 P220 P221A48-V223 HydrophobicContact CB-CG2 3.96Å; W55-V223 HydrophobicContact CB-CG2 3.74Å; W55-V223 HydrophobicContact CD2-CG1 3.91Å; W55-V223 HydrophobicContact CD2-CG2 3.74Å; W55-V223 HydrophobicContact CE3-CG1 4.36Å; W55-V223 HydrophobicContact CE3-CG2 4.18Å; W55-V223 HydrophobicContact CG-CG1 4.32Å; W55-V223 HydrophobicContact CG-CG2 3.51Å; W55-V223 HydrophobicContact CH2-CG1 4.33Å; W55-V223 HydrophobicContact CZ2-CG1 3.86Å; L162-V223 HydrophobicContact CD2-CG1 3.5Å; L162-V223 VanDerWaalsContact CD2-CG1 3.5Å; T167-V223 CarbonylContact C-O 3.49Å; T167-V223 WeakPolarHBondContact CA-O 3.22Å; T167-V223 HydrophobicContact CG2-CB 4.39Å; T167-V223 HydrophobicContact CG2-CG1 4.47Å; T167-V223 HydrophobicContact CG2-CG2 4.1Å; V168-V223 PolarHBondContact N-O 3.03Å; F219-V223 HydrophobicContact CD1-CG1 4.17Å; P220-V223 HydrophobicContact CB-CG2 4.05Å; P220-V223 HydrophobicContact CG-CG2 4.14Å; P220-V223 WeakPolarHBondContact O-CB 3.49Å; P220-V223 WeakPolarHBondContact O-CG2 3.17Å; P220-V223 PolarHBondContact O-N 3.24Å; P220-V223 VanDerWaalsContact O-N 3.17Å; P221-V223 VanDerWaalsContact C-N 3.34Å; P221-V223 PolarHBondContact O-N 3.19Å
224V98.5Very high88Confident2 Ų230.8 Ų30.81%0.01217%0.173CC..EExtended strand (participates in β ladder)trans-124.6128172.8-1780000109.2L162 V168 I187 G222 I226L162-V224 HydrophobicContact CD1-CG2 4.05Å; L162-V224 HydrophobicContact CD2-CG2 3.92Å; V168-V224 HydrophobicContact CG2-CB 4.03Å; V168-V224 HydrophobicContact CG2-CG1 3.83Å; V168-V224 HydrophobicContact CG2-CG2 3.83Å; I187-V224 HydrophobicContact CD1-CB 4.05Å; I187-V224 HydrophobicContact CD1-CG1 3.72Å; I187-V224 HydrophobicContact CD1-CG2 4.03Å; I187-V224 HydrophobicContact CG2-CB 4.32Å; I187-V224 HydrophobicContact CG2-CG2 4.36Å; G222-V224 VanDerWaalsContact C-N 3.34Å; G222-V224 PolarHBondContact O-N 3.41Å; V224-I226 HydrophobicContact CG1-CG1 4.25Å
225N98.7Very high90.6Very high0 Ų025.1 Ų25.10%015%0.149CC..EExtended strand (participates in β ladder)trans-130.5137.3176.3-48-89.8000108.3F2 D4 A41 V168 V169 V170 G222F2-N225 CarbonylContact O-C 3.56Å; F2-N225 WeakPolarHBondContact O-CA 3.35Å; D4-N225 PolarHBondContact N-OD1 2.8Å; D4-N225 VanDerWaalsContact N-OD1 3.16Å; A41-N225 HydrophobicContact CB-CB 3.87Å; V168-N225 PolarHBondContact O-N 3.16Å; V168-N225 PolarHBondContact O-ND2 3.01Å; V168-N225 VanDerWaalsContact O-ND2 3.11Å; V169-N225 CarbonylContact C-O 3.51Å; V169-N225 WeakPolarHBondContact CA-O 3.37Å; V169-N225 HydrophobicContact CG2-CB 4.42Å; V170-N225 PolarHBondContact N-O 3.48Å; G222-N225 PolarHBondContact O-ND2 3.33Å
226I98.8Very high93Very high2 Ų226.3 Ų26.31%0.0115%0.152CC..EExtended strand (participates in β ladder)trans-125.9115.2-176.4-47.8-177.3000109.2F2 V170 P172 A180 L181 V224 P228F2-I226 HydrophobicContact CB-CB 4.2Å; F2-I226 HydrophobicContact CB-CG1 4.47Å; F2-I226 HydrophobicContact CD1-CG1 4.36Å; F2-I226 PolarHBondContact N-O 2.67Å; F2-I226 PolarHBondContact O-N 3.44Å; V170-I226 HydrophobicContact CB-CG1 4.35Å; V170-I226 CarbonylContact O-C 3.49Å; V170-I226 WeakPolarHBondContact O-CA 3.19Å; P172-I226 HydrophobicContact CG-CG2 4.14Å; A180-I226 HydrophobicContact CB-CG2 4.39Å; A180-I226 WeakPolarHBondContact O-CD1 3.43Å; L181-I226 HydrophobicContact CD2-CG2 4.13Å; V224-I226 HydrophobicContact CG1-CG1 4.25Å; I226-P228 WeakPolarHBondContact O-CD 3.31Å
227V98.7Very high95.1Very high0 Ų024.9 Ų24.90%014%0.142CC..  trans-120.878.6-172.9-73.40000110.1I3 A33 V38 A41 V169 V170 K171 T234I3-V227 HydrophobicContact CD1-CG1 4.07Å; I3-V227 HydrophobicContact CG1-CG1 4.29Å; A33-V227 HydrophobicContact CB-CB 3.67Å; A33-V227 HydrophobicContact CB-CG1 4.23Å; V38-V227 HydrophobicContact CG2-CG2 4.41Å; A41-V227 HydrophobicContact CB-CG1 3.79Å; V169-V227 HydrophobicContact CG1-CG2 3.63Å; V170-V227 WeakPolarHBondContact O-CG2 3.46Å; V170-V227 PolarHBondContact O-N 3.21Å; K171-V227 HydrophobicContact CB-CG2 4.49Å; V227-T234 HydrophobicContact CB-CG2 4.34Å; V227-T234 HydrophobicContact CG2-CG2 4.3Å; V227-T234 WeakPolarHBondContact O-CG2 3.23Å
228P98.7Very high96.9Very high0 Ų024.8 Ų24.80%014%0.141CC..  trans-63.1146173.327.8-36.8000111.7M1 F16 V30 A33 P172 P177 L181 I226M1-P228 HydrophobicContact CG-CG 4.29Å; F16-P228 HydrophobicContact CE1-CB 4.19Å; F16-P228 HydrophobicContact CZ-CB 4.05Å; V30-P228 HydrophobicContact CG1-CB 3.86Å; V30-P228 HydrophobicContact CG1-CG 3.59Å; A33-P228 WeakPolarHBondContact CB-O 3.37Å; A33-P228 PolarHBondContact N-O 3.05Å; P172-P228 HydrophobicContact CG-CB 3.98Å; P177-P228 HydrophobicContact CB-CB 3.99Å; L181-P228 HydrophobicContact CD2-CG 4.09Å; I226-P228 WeakPolarHBondContact O-CD 3.31Å
229G98.4Very high97.6Very high0 Ų023.7 Ų23.70%013%0.133CC..  trans164.7-174.1177.400000111.1K171 T234K171-G229 WeakPolarHBondContact CE-O 3.38Å; K171-G229 PolarHBondContact NZ-O 2.8Å; G229-T234 VanDerWaalsContact CA-OG1 3.26Å; G229-T234 WeakPolarHBondContact CA-OG1 3.35Å
230Y98.4Very high97.9Very high90 Ų9024.9 Ų24.935%0.35314%0.141SC..  trans-77.1143.4-176.1-71.1-76000112.9F16 E32 E174 I233 T234 G235F16-Y230 HydrophobicContact CB-CE2 3.93Å; F16-Y230 HydrophobicContact CG-CE2 4.43Å; E32-Y230 HydrophobicContact CG-CD2 4.29Å; E174-Y230 HydrophobicContact CB-CD1 4.1Å; E174-Y230 HydrophobicContact CB-CE1 4.27Å; E174-Y230 HydrophobicContact CG-CD1 3.76Å; E174-Y230 HydrophobicContact CG-CE1 4.02Å; Y230-I233 PolarHBondContact O-N 3.29Å; Y230-I233 VanDerWaalsContact O-N 3.14Å; Y230-T234 PolarHBondContact N-OG1 2.87Å; Y230-T234 WeakPolarHBondContact O-CB 3.35Å; Y230-T234 PolarHBondContact O-N 2.94Å; Y230-T234 PolarHBondContact O-OG1 3.12Å; Y230-G235 PolarHBondContact O-N 3.47Å
231G97.9Very high98.2Very high27 Ų2725.6 Ų25.628%0.27814%0.144SC..Iπ-helixtrans-50.6-53.7177.300000114.2E174 I233 G235 E236E174-G231 PolarHBondContact OE1-N 3.15Å; G231-I233 PolarHBondContact O-N 3.45Å; G231-I233 VanDerWaalsContact O-N 3.09Å; G231-G235 CarbonylContact O-C 3.55Å; G231-G235 WeakPolarHBondContact O-CA 3.5Å; G231-G235 PolarHBondContact O-N 3.3Å; G231-E236 PolarHBondContact O-N 2.9Å
232P97.7Very high98.3Very high98 Ų9832.5 Ų32.564%0.63616%0.161SC*.Iπ-helixtrans-65.4-7.9-179.9-24.635.4000116
233I98.2Very high98.3Very high74 Ų7437.4 Ų37.438%0.37918%0.184SC..Iπ-helixtrans-115.6-65.3-179.8-58.7174000109K34 Y230 G231 A237K34-I233 HydrophobicContact CB-CG2 4.3Å; K34-I233 HydrophobicContact CG-CG2 4.01Å; Y230-I233 PolarHBondContact O-N 3.29Å; Y230-I233 VanDerWaalsContact O-N 3.14Å; G231-I233 PolarHBondContact O-N 3.45Å; G231-I233 VanDerWaalsContact O-N 3.09Å; I233-A237 VanDerWaalsContact O-CB 3.24Å; I233-A237 WeakPolarHBondContact O-CB 3.17Å; I233-A237 PolarHBondContact O-N 3.05Å
234T98.6Very high98.3Very high0 Ų037.5 Ų37.50%019%0.185CC..Iπ-helixtrans-74-43-176.7-36.40000111.8A33 V38 K171 V227 G229 Y230 A237 V238A33-T234 HydrophobicContact CB-CG2 3.71Å; A33-T234 WeakPolarHBondContact O-CB 3.17Å; A33-T234 PolarHBondContact O-OG1 2.98Å; V38-T234 HydrophobicContact CG2-CG2 3.81Å; K171-T234 HydrophobicContact CG-CG2 3.86Å; V227-T234 HydrophobicContact CB-CG2 4.34Å; V227-T234 HydrophobicContact CG2-CG2 4.3Å; V227-T234 WeakPolarHBondContact O-CG2 3.23Å; G229-T234 VanDerWaalsContact CA-OG1 3.26Å; G229-T234 WeakPolarHBondContact CA-OG1 3.35Å; Y230-T234 PolarHBondContact N-OG1 2.87Å; Y230-T234 WeakPolarHBondContact O-CB 3.35Å; Y230-T234 PolarHBondContact O-N 2.94Å; Y230-T234 PolarHBondContact O-OG1 3.12Å; T234-A237 PolarHBondContact O-N 3.37Å; T234-V238 WeakPolarHBondContact O-CG2 3.29Å; T234-V238 PolarHBondContact O-N 3.25Å
235G98.3Very high98.3Very high4 Ų439.9 Ų39.94%0.04120%0.197CC..Iπ-helixtrans-66.6-43.5179.700000111.9Y230 G231 V238 A239Y230-G235 PolarHBondContact O-N 3.47Å; G231-G235 CarbonylContact O-C 3.55Å; G231-G235 WeakPolarHBondContact O-CA 3.5Å; G231-G235 PolarHBondContact O-N 3.3Å; G235-V238 PolarHBondContact O-N 3.07Å; G235-A239 PolarHBondContact O-N 2.78Å
236E98.1Very high98.3Very high117 Ų11740 Ų4055%0.54720%0.198SC..Hα-helixtrans-60.1-47.4172.1-174.8173.2-14300111.2G231 V238 A239 C240G231-E236 PolarHBondContact O-N 2.9Å; E236-V238 VanDerWaalsContact C-N 3.3Å; E236-V238 PolarHBondContact O-N 3.48Å; E236-A239 PolarHBondContact O-N 3.14Å; E236-A239 VanDerWaalsContact O-N 3.11Å; E236-C240 WeakPolarHBondContact O-CB 3.35Å; E236-C240 PolarHBondContact O-N 3.41Å; E236-C240 PolarHBondContact O-SG 3Å; E236-C240 VanDerWaalsContact O-SG 3.38Å
237A98.6Very high98.3Very high2 Ų239.9 Ų39.92%0.01720%0.197CC..Hα-helixtrans-54.8-44.5176.200000112.2Q35 V38 I233 T234 H241Q35-A237 VanDerWaalsContact OE1-CB 3.23Å; V38-A237 HydrophobicContact CB-CB 4.13Å; V38-A237 HydrophobicContact CG1-CB 4.2Å; V38-A237 HydrophobicContact CG2-CB 3.96Å; I233-A237 VanDerWaalsContact O-CB 3.24Å; I233-A237 WeakPolarHBondContact O-CB 3.17Å; I233-A237 PolarHBondContact O-N 3.05Å; T234-A237 PolarHBondContact O-N 3.37Å; A237-H241 VanDerWaalsContact O-CB 3.29Å; A237-H241 WeakPolarHBondContact O-CB 3.31Å; A237-H241 PolarHBondContact O-N 2.87Å
238V98.6Very high98.3Very high0 Ų039.9 Ų39.90%020%0.197CC..Hα-helixtrans-63.5-45.1176.3171.40000111.7V38 I144 V169 T234 G235 E236V38-V238 HydrophobicContact CG1-CG2 3.78Å; V38-V238 HydrophobicContact CG2-CG2 4.08Å; I144-V238 HydrophobicContact CD1-CG1 4.47Å; I144-V238 HydrophobicContact CG1-CG1 4.45Å; V169-V238 HydrophobicContact CG1-CG2 4.3Å; T234-V238 WeakPolarHBondContact O-CG2 3.29Å; T234-V238 PolarHBondContact O-N 3.25Å; G235-V238 PolarHBondContact O-N 3.07Å; E236-V238 VanDerWaalsContact C-N 3.3Å; E236-V238 PolarHBondContact O-N 3.48Å
239A98.3Very high98.3Very high1 Ų140.5 Ų40.51%0.00820%0.2CC..Hα-helixtrans-68.2-38.2-178.100000112.8G235 E236 I259 A262 K269G235-A239 PolarHBondContact O-N 2.78Å; E236-A239 PolarHBondContact O-N 3.14Å; E236-A239 VanDerWaalsContact O-N 3.11Å; A239-I259 HydrophobicContact CB-CD1 3.77Å; A239-A262 HydrophobicContact CB-CB 3.91Å; A239-K269 WeakPolarHBondContact O-CE 3.13Å; A239-K269 PolarHBondContact O-NZ 3.34Å
240C98.3Very high98.3Very high26 Ų2641 Ų4118%0.17620%0.203CC..Hα-helixtrans-82.5-17.2-179.1-64.50000113.1E236 R242 H266E236-C240 WeakPolarHBondContact O-CB 3.35Å; E236-C240 PolarHBondContact O-N 3.41Å; E236-C240 PolarHBondContact O-SG 3Å; E236-C240 VanDerWaalsContact O-SG 3.38Å; C240-R242 PolarHBondContact O-N 3.35Å; C240-H266 WeakPolarHBondContact O-CB 3.42Å; C240-H266 PolarHBondContact SG-CD2 3.24Å
241H98.5Very high98.3Very high24 Ų2437.8 Ų37.811%0.11120%0.197CC..  trans-62.3119.7-174.6-162.5-78.5000112.8D39 V42 A237 Q243 V244 K269D39-H241 IonicContact OD1-CD2 2.85Å; D39-H241 PolarHBondContact OD1-CD2 3.17Å; D39-H241 IonicContact OD1-NE2 3.36Å; D39-H241 PolarHBondContact OD1-NE2 2.98Å; V42-H241 WeakPolarHBondContact CG1-CE1 3.32Å; V42-H241 WeakPolarHBondContact CG1-ND1 3.41Å; A237-H241 VanDerWaalsContact O-CB 3.29Å; A237-H241 WeakPolarHBondContact O-CB 3.31Å; A237-H241 PolarHBondContact O-N 2.87Å; H241-Q243 PolarHBondContact ND1-N 3.39Å; H241-Q243 VanDerWaalsContact ND1-N 3.14Å; H241-Q243 PolarHBondContact O-N 3.41Å; H241-Q243 VanDerWaalsContact O-N 3.15Å; H241-V244 HydrophobicContact CB-CG2 3.89Å; H241-V244 PolarHBondContact O-N 3.17Å; H241-K269 WeakPolarHBondContact O-CE 3.4Å; H241-K269 PolarHBondContact O-NZ 3.47Å
242R97Very high98.3Very high215 Ų21538.8 Ų38.881%0.81120%0.2SC*.THydrogen-bonded Turntrans-64-23.4-174.5-69-174.1177.5-166.1-1.3114.7C240 V244C240-R242 PolarHBondContact O-N 3.35Å; R242-V244 VanDerWaalsContact C-N 3.35Å
243Q97.6Very high98.3Very high103 Ų10334.7 Ų34.748%0.48117%0.173SC..THydrogen-bonded Turntrans-97.632.9174.3-51-180-34.700112V42 R46 H241V42-Q243 HydrophobicContact CG1-CB 3.79Å; V42-Q243 WeakPolarHBondContact CG1-O 3.43Å; R46-Q243 HydrophobicContact CG-CB 4.24Å; R46-Q243 PolarHBondContact NE-O 2.95Å; R46-Q243 PolarHBondContact NH2-O 3.02Å; H241-Q243 PolarHBondContact ND1-N 3.39Å; H241-Q243 VanDerWaalsContact ND1-N 3.14Å; H241-Q243 PolarHBondContact O-N 3.41Å; H241-Q243 VanDerWaalsContact O-N 3.15Å
244V98.6Very high98.3Very high3 Ų338.3 Ų38.32%0.01819%0.188CC..  trans-111.2125.2162.8169.80000106.7V42 V140 H241 R242 K246 V247 K269V42-V244 HydrophobicContact CG1-CG2 4.37Å; V42-V244 HydrophobicContact CG2-CG2 3.83Å; V140-V244 HydrophobicContact CG1-CG2 4.29Å; H241-V244 HydrophobicContact CB-CG2 3.89Å; H241-V244 PolarHBondContact O-N 3.17Å; R242-V244 VanDerWaalsContact C-N 3.35Å; V244-K246 WeakPolarHBondContact CG1-O 3.24Å; V244-V247 HydrophobicContact CG1-CG2 4Å; V244-K269 HydrophobicContact CB-CD 4.25Å; V244-K269 HydrophobicContact CG1-CD 4.22Å; V244-K269 WeakPolarHBondContact O-CD 3.37Å; V244-K269 WeakPolarHBondContact O-CE 3.33Å; V244-K269 WeakPolarHBondContact O-CG 3.48Å
245D98.4Very high98.3Very high52 Ų5241 Ų4128%0.27821%0.205SC..  trans-86.9-28.3-176.5-53.2-49.3000112.1R46 V138 G139 V140 R270R46-D245 IonicContact CZ-OD1 3.7Å; R46-D245 IonicContact CZ-OD2 2.64Å; R46-D245 IonicContact NH1-OD1 3.71Å; R46-D245 PolarHBondContact NH1-OD1 2.65Å; R46-D245 IonicContact NH1-OD2 2.8Å; R46-D245 PolarHBondContact NH1-OD2 2.82Å; R46-D245 IonicContact NH2-OD1 2.71Å; R46-D245 PolarHBondContact NH2-OD1 3.5Å; R46-D245 IonicContact NH2-OD2 3.64Å; R46-D245 PolarHBondContact NH2-OD2 3.41Å; V138-D245 HydrophobicContact CG1-CB 3.74Å; G139-D245 WeakPolarHBondContact CA-OD2 3.49Å; V140-D245 PolarHBondContact N-OD2 3.21Å; V140-D245 PolarHBondContact O-N 3.3Å; D245-R270 PolarHBondContact O-N 3.43Å
246K98.6Very high98.3Very high2 Ų240.8 Ų40.81%0.00920%0.203CC..EExtended strand (participates in β ladder)trans-140.1142-178.5169.6170.5173.958.50111.1V138 V140 C141 G142 V244 R270 S272 S490 Y491V138-K246 HydrophobicContact CG1-CB 4.05Å; V138-K246 HydrophobicContact CG2-CD 4.4Å; V140-K246 PolarHBondContact O-N 2.78Å; C141-K246 CarbonylContact C-O 3.39Å; C141-K246 VanDerWaalsContact CA-O 3.32Å; C141-K246 WeakPolarHBondContact CA-O 3.35Å; G142-K246 PolarHBondContact N-O 3.36Å; V244-K246 WeakPolarHBondContact CG1-O 3.24Å; K246-R270 CarbonylContact C-O 3.4Å; K246-R270 WeakPolarHBondContact CA-O 3.24Å; K246-R270 HydrophobicContact CB-CB 4.03Å; K246-R270 HydrophobicContact CG-CB 4.21Å; K246-S272 PolarHBondContact NZ-OG 3.1Å; K246-S490 WeakPolarHBondContact CD-O 3.06Å; K246-S490 WeakPolarHBondContact CE-O 3.38Å; K246-Y491 HydrophobicContact CD-CD1 4.04Å; K246-Y491 HydrophobicContact CD-CE1 4.08Å
247V98.7Very high98.3Very high0 Ų040.8 Ų40.80%020%0.201CC..EExtended strand (participates in β ladder)trans-113139163.4-179.40000109.6G142 I144 V244 I259 K269 R270 L271 S272G142-V247 CarbonylContact O-C 3.51Å; G142-V247 VanDerWaalsContact O-CA 3.29Å; G142-V247 WeakPolarHBondContact O-CA 3.41Å; I144-V247 HydrophobicContact CD1-CG1 4.35Å; V244-V247 HydrophobicContact CG1-CG2 4Å; V247-I259 HydrophobicContact CG1-CG2 3.8Å; V247-K269 HydrophobicContact CG2-CD 4.14Å; V247-R270 PolarHBondContact N-O 2.8Å; V247-L271 HydrophobicContact CB-CD1 3.96Å; V247-L271 HydrophobicContact CG1-CD1 4.18Å; V247-L271 WeakPolarHBondContact O-CA 3.39Å; V247-L271 WeakPolarHBondContact O-CD1 3.33Å; V247-S272 PolarHBondContact O-N 2.99Å; V247-S272 VanDerWaalsContact O-N 3.13Å
248A98.8Very high98.3Very high0 Ų046.1 Ų46.10%023%0.228CC..EExtended strand (participates in β ladder)trans-122.8115.7169.200000108G142 I144 K157 Y491G142-A248 PolarHBondContact O-N 2.85Å; I144-A248 PolarHBondContact N-O 3.02Å; K157-A248 HydrophobicContact CD-CB 4.24Å; A248-Y491 WeakPolarHBondContact CB-OH 3.3Å
249F98.8Very high98.3Very high13 Ų1346.6 Ų46.66%0.05723%0.231CC..EExtended strand (participates in β ladder)trans-123.1133.7-175.2171.1-94.2000110.2I144 V255 I259 S272 L273 E274 L275I144-F249 HydrophobicContact CB-CD2 3.87Å; I144-F249 HydrophobicContact CD1-CD2 4.46Å; I144-F249 HydrophobicContact CG2-CD2 3.66Å; I144-F249 HydrophobicContact CG2-CE2 4Å; F249-V255 HydrophobicContact CE1-CB 4.38Å; F249-V255 HydrophobicContact CE1-CG1 4.28Å; F249-V255 HydrophobicContact CE2-CB 4.46Å; F249-V255 HydrophobicContact CE2-CG1 3.65Å; F249-V255 HydrophobicContact CZ-CB 3.74Å; F249-V255 HydrophobicContact CZ-CG1 3.41Å; F249-V255 VanDerWaalsContact CZ-CG1 3.41Å; F249-I259 HydrophobicContact CB-CG1 4.49Å; F249-I259 HydrophobicContact CB-CG2 4.28Å; F249-I259 HydrophobicContact CD2-CD1 4.46Å; F249-I259 HydrophobicContact CD2-CG1 3.97Å; F249-I259 HydrophobicContact CE2-CG1 4.36Å; F249-I259 HydrophobicContact CG-CG1 4.09Å; F249-S272 PolarHBondContact N-O 3.35Å; F249-L273 HydrophobicContact CB-CD2 3.91Å; F249-L273 HydrophobicContact CD1-CD2 3.99Å; F249-L273 HydrophobicContact CG-CD2 4.39Å; F249-L273 WeakPolarHBondContact O-CA 2.99Å; F249-E274 PolarHBondContact O-N 2.94Å; F249-L275 HydrophobicContact CD1-CD2 3.82Å; F249-L275 HydrophobicContact CE1-CD2 3.72Å
250T98.8Very high98.3Very high10 Ų1051.5 Ų51.56%0.06126%0.255CS..EExtended strand (participates in β ladder)trans-120.4130.6164.4-55.80000109.2I144 P146 M153 K157 E274I144-T250 PolarHBondContact O-N 3.4Å; P146-T250 WeakPolarHBondContact CD-O 3.31Å; P146-T250 HydrophobicContact CG-CG2 3.82Å; M153-T250 HydrophobicContact SD-CG2 4.06Å; K157-T250 VanDerWaalsContact CE-OG1 3.28Å; K157-T250 WeakPolarHBondContact CE-OG1 3.33Å; K157-T250 PolarHBondContact NZ-OG1 3.18Å; T250-E274 WeakPolarHBondContact CA-O 3.42Å; T250-E274 HydrophobicContact CG2-CB 3.9Å; T250-E274 WeakPolarHBondContact CG2-O 3.29Å; T250-E274 WeakPolarHBondContact OG1-CB 3.37Å
251G98.3Very high98.3Very high22 Ų2253.8 Ų53.823%0.22727%0.268CS..SBendtrans165.2-152.8-177.700000113.3E274 L275 G276G251-E274 PolarHBondContact N-O 3.1Å; G251-E274 VanDerWaalsContact N-O 3.12Å; G251-L275 VanDerWaalsContact O-CA 3.29Å; G251-L275 WeakPolarHBondContact O-CA 3.45Å; G251-G276 PolarHBondContact O-N 3.43Å
252S97.7Very high98.2Very high49 Ų4953.1 Ų53.134%0.34327%0.267SS..  trans-73.2151.5-177.473.10000112.6E254 V255 G256S252-E254 PolarHBondContact O-N 3.33Å; S252-V255 PolarHBondContact O-N 2.93Å; S252-V255 WeakPolarHBondContact OG-CG2 3.33Å; S252-V255 PolarHBondContact OG-N 3.42Å; S252-G256 PolarHBondContact O-N 2.93Å
253T98Very high98.3Very high11 Ų1143 Ų437%0.06723%0.229CC..Hα-helixtrans-61.3-32175.3-61.60000112.8K257 L275 Y431 M476T253-K257 WeakPolarHBondContact O-CG 3.38Å; T253-K257 PolarHBondContact O-N 3.14Å; T253-L275 HydrophobicContact CG2-CD1 4.37Å; T253-Y431 WeakPolarHBondContact OG1-CE1 3.29Å; T253-M476 HydrophobicContact CG2-CB 4.06Å; T253-M476 HydrophobicContact CG2-CE 3.91Å; T253-M476 PolarHBondContact OG1-O 3.47Å
254E97.5Very high98.3Very high150 Ų15039.8 Ų39.870%0.70122%0.224SC*.Hα-helixtrans-62.5-52.3175.3-175.5-179.3178.500111.6S252 G256 K257 L258S252-E254 PolarHBondContact O-N 3.33Å; E254-G256 VanDerWaalsContact C-N 3.33Å; E254-G256 PolarHBondContact O-N 2.72Å; E254-K257 WeakPolarHBondContact O-CB 3.21Å; E254-K257 PolarHBondContact O-N 3.5Å; E254-L258 PolarHBondContact O-N 2.91Å
255V98.4Very high98.2Very high57 Ų5746.3 Ų46.335%0.34525%0.254SS..Hα-helixtrans-68.2-35.6178.5177.20000110.9F249 S252 K257 L258 I259F249-V255 HydrophobicContact CE1-CB 4.38Å; F249-V255 HydrophobicContact CE1-CG1 4.28Å; F249-V255 HydrophobicContact CE2-CB 4.46Å; F249-V255 HydrophobicContact CE2-CG1 3.65Å; F249-V255 HydrophobicContact CZ-CB 3.74Å; F249-V255 HydrophobicContact CZ-CG1 3.41Å; F249-V255 VanDerWaalsContact CZ-CG1 3.41Å; S252-V255 PolarHBondContact O-N 2.93Å; S252-V255 WeakPolarHBondContact OG-CG2 3.33Å; S252-V255 PolarHBondContact OG-N 3.42Å; V255-K257 PolarHBondContact O-N 2.77Å; V255-L258 WeakPolarHBondContact O-CB 3.2Å; V255-L258 PolarHBondContact O-N 2.98Å; V255-I259 HydrophobicContact CG1-CG1 4.23Å; V255-I259 WeakPolarHBondContact O-CG1 3.39Å; V255-I259 PolarHBondContact O-N 2.98Å
256G98.4Very high98.1Very high0 Ų047 Ų470%026%0.255CS..Hα-helixtrans-55.5-37.1174.400000113.4S252 E254 M260S252-G256 PolarHBondContact O-N 2.93Å; E254-G256 VanDerWaalsContact C-N 3.33Å; E254-G256 PolarHBondContact O-N 2.72Å; G256-M260 WeakPolarHBondContact O-CB 3.18Å; G256-M260 PolarHBondContact O-N 3.29Å
257K98.3Very high97.8Very high117 Ų11749.6 Ų49.651%0.50928%0.283SS..Hα-helixtrans-65.9-42.8173.3-69.4171.7-177.9178.10112T253 E254 V255 M260 T261T253-K257 WeakPolarHBondContact O-CG 3.38Å; T253-K257 PolarHBondContact O-N 3.14Å; E254-K257 WeakPolarHBondContact O-CB 3.21Å; E254-K257 PolarHBondContact O-N 3.5Å; V255-K257 PolarHBondContact O-N 2.77Å; K257-M260 WeakPolarHBondContact O-CB 3.38Å; K257-M260 PolarHBondContact O-N 3.22Å; K257-T261 PolarHBondContact O-N 3.46Å; K257-T261 PolarHBondContact O-OG1 3.22Å
258L98.4Very high97.7Very high113 Ų11356.7 Ų56.759%0.59232%0.32SS*.Hα-helixtrans-61.8-43.9176.8-59.3177.6000111.3E254 V255 M260 T261 A262E254-L258 PolarHBondContact O-N 2.91Å; V255-L258 WeakPolarHBondContact O-CB 3.2Å; V255-L258 PolarHBondContact O-N 2.98Å; L258-M260 VanDerWaalsContact C-N 3.32Å; L258-M260 PolarHBondContact O-N 3.4Å; L258-T261 PolarHBondContact O-N 3.35Å; L258-A262 WeakPolarHBondContact O-CB 3.28Å; L258-A262 PolarHBondContact O-N 3.15Å
259I98.4Very high97.7Very high11 Ų1157.5 Ų57.56%0.05632%0.324CS..Hα-helixtrans-60.8-42174.9-63.7-64.5000111.1I144 A239 V247 F249 V255 A262 C263 L271 L273I144-I259 HydrophobicContact CD1-CD1 3.86Å; A239-I259 HydrophobicContact CB-CD1 3.77Å; V247-I259 HydrophobicContact CG1-CG2 3.8Å; F249-I259 HydrophobicContact CB-CG1 4.49Å; F249-I259 HydrophobicContact CB-CG2 4.28Å; F249-I259 HydrophobicContact CD2-CD1 4.46Å; F249-I259 HydrophobicContact CD2-CG1 3.97Å; F249-I259 HydrophobicContact CE2-CG1 4.36Å; F249-I259 HydrophobicContact CG-CG1 4.09Å; V255-I259 HydrophobicContact CG1-CG1 4.23Å; V255-I259 WeakPolarHBondContact O-CG1 3.39Å; V255-I259 PolarHBondContact O-N 2.98Å; I259-A262 PolarHBondContact O-N 3.36Å; I259-C263 WeakPolarHBondContact O-CB 3.29Å; I259-C263 PolarHBondContact O-N 3.42Å; I259-C263 PolarHBondContact O-SG 3.36Å; I259-L271 HydrophobicContact CG2-CD1 3.83Å; I259-L271 HydrophobicContact CG2-CD2 4.48Å; I259-L273 HydrophobicContact CG2-CD2 4.42Å
260M98Very high97.6Very high103 Ų10360.5 Ų60.551%0.50733%0.334SS..Hα-helixtrans-62.7-45.1177.1-174.3173.9179.600112.2G256 K257 L258 C263 G264 L271 F479G256-M260 WeakPolarHBondContact O-CB 3.18Å; G256-M260 PolarHBondContact O-N 3.29Å; K257-M260 WeakPolarHBondContact O-CB 3.38Å; K257-M260 PolarHBondContact O-N 3.22Å; L258-M260 VanDerWaalsContact C-N 3.32Å; L258-M260 PolarHBondContact O-N 3.4Å; M260-C263 PolarHBondContact O-N 3.45Å; M260-G264 PolarHBondContact O-N 2.92Å; M260-L271 HydrophobicContact CB-CD2 3.76Å; M260-L271 HydrophobicContact CG-CD2 4Å; M260-F479 HydrophobicContact SD-CE1 4.09Å; M260-F479 HydrophobicContact SD-CZ 4.45Å
261T98.2Very high97.6Very high74 Ų7461.2 Ų61.245%0.45434%0.338SS..Hα-helixtrans-58.1-51.7174.1-59.90000110.9K257 L258 C263 G264 E265K257-T261 PolarHBondContact O-N 3.46Å; K257-T261 PolarHBondContact O-OG1 3.22Å; L258-T261 PolarHBondContact O-N 3.35Å; T261-C263 VanDerWaalsContact C-N 3.34Å; T261-C263 PolarHBondContact O-N 3.26Å; T261-G264 PolarHBondContact O-N 3.36Å; T261-G264 VanDerWaalsContact O-N 3.1Å; T261-E265 HydrophobicContact CG2-CG 4.25Å; T261-E265 WeakPolarHBondContact CG2-OE1 3.17Å; T261-E265 WeakPolarHBondContact O-CG 3.26Å; T261-E265 PolarHBondContact O-N 2.97Å
262A98Very high97.6Very high11 Ų1160.3 Ų60.39%0.09133%0.328CS..Hα-helixtrans-58.7-42.1178.800000112.9A239 L258 I259 G264 H266A239-A262 HydrophobicContact CB-CB 3.91Å; L258-A262 WeakPolarHBondContact O-CB 3.28Å; L258-A262 PolarHBondContact O-N 3.15Å; I259-A262 PolarHBondContact O-N 3.36Å; A262-G264 VanDerWaalsContact C-N 3.34Å; A262-G264 PolarHBondContact O-N 3.39Å; A262-H266 WeakPolarHBondContact O-CB 3.19Å; A262-H266 PolarHBondContact O-CD2 2.83Å; A262-H266 VanDerWaalsContact O-CD2 3.31Å; A262-H266 PolarHBondContact O-N 2.95Å
263C97.7Very high97.6Very high3 Ų358.2 Ų58.22%0.0231%0.313CS..Hα-helixtrans-63.8-40176.5-71.60000112.1I259 M260 T261 L268 K269 L271I259-C263 WeakPolarHBondContact O-CB 3.29Å; I259-C263 PolarHBondContact O-N 3.42Å; I259-C263 PolarHBondContact O-SG 3.36Å; M260-C263 PolarHBondContact O-N 3.45Å; T261-C263 VanDerWaalsContact C-N 3.34Å; T261-C263 PolarHBondContact O-N 3.26Å; C263-L268 WeakPolarHBondContact O-CA 3.34Å; C263-L268 PolarHBondContact O-N 2.96Å; C263-K269 HydrophobicContact CB-CB 4.08Å; C263-K269 PolarHBondContact O-N 2.74Å; C263-K269 VanDerWaalsContact O-N 3.13Å; C263-L271 HydrophobicContact CB-CD2 4.41Å
264G97.6Very high97.7Very high35 Ų3558 Ų5836%0.36131%0.311SS..Hα-helixtrans-64.9-52.4176.700000112.2M260 T261 A262 H266 L268M260-G264 PolarHBondContact O-N 2.92Å; T261-G264 PolarHBondContact O-N 3.36Å; T261-G264 VanDerWaalsContact O-N 3.1Å; A262-G264 VanDerWaalsContact C-N 3.34Å; A262-G264 PolarHBondContact O-N 3.39Å; G264-H266 PolarHBondContact O-N 3.23Å; G264-L268 PolarHBondContact O-N 2.73Å
265E97.4Very high97.7Very high140 Ų14051.3 Ų51.365%0.65428%0.28SS*.Hα-helixtrans-67.9-35.4-175.8-70.2-179.1170.600113.2T261T261-E265 HydrophobicContact CG2-CG 4.25Å; T261-E265 WeakPolarHBondContact CG2-OE1 3.17Å; T261-E265 WeakPolarHBondContact O-CG 3.26Å; T261-E265 PolarHBondContact O-N 2.97Å
266H96.2Very high97.5Very high65 Ų6548.7 Ų48.730%0.30127%0.265SS..THydrogen-bonded Turntrans-108.222.7-170.9-60.4-77.4000114.8C240 A262 G264 K269C240-H266 WeakPolarHBondContact O-CB 3.42Å; C240-H266 PolarHBondContact SG-CD2 3.24Å; A262-H266 WeakPolarHBondContact O-CB 3.19Å; A262-H266 PolarHBondContact O-CD2 2.83Å; A262-H266 VanDerWaalsContact O-CD2 3.31Å; A262-H266 PolarHBondContact O-N 2.95Å; G264-H266 PolarHBondContact O-N 3.23Å; H266-K269 PolarHBondContact O-NZ 3.01Å
267G92.9Very high97.5Very high57 Ų5748.9 Ų48.959%0.58827%0.266SS*.THydrogen-bonded Turntrans148.311.6168.400000117.5K269G267-K269 PolarHBondContact O-N 3.35Å
268L96.6Very high97.5Very high150 Ų15043.4 Ų43.479%0.78524%0.242SC*.  trans4844.8-173.7-62.1177.3000111.9C263 G264C263-L268 WeakPolarHBondContact O-CA 3.34Å; C263-L268 PolarHBondContact O-N 2.96Å; G264-L268 PolarHBondContact O-N 2.73Å
269K97.8Very high97.5Very high17 Ų1738.1 Ų38.17%0.07422%0.215CC..  trans-63.1147.4-175.3-55-177.5176.877.90110A239 H241 V244 V247 C263 H266 G267A239-K269 WeakPolarHBondContact O-CE 3.13Å; A239-K269 PolarHBondContact O-NZ 3.34Å; H241-K269 WeakPolarHBondContact O-CE 3.4Å; H241-K269 PolarHBondContact O-NZ 3.47Å; V244-K269 HydrophobicContact CB-CD 4.25Å; V244-K269 HydrophobicContact CG1-CD 4.22Å; V244-K269 WeakPolarHBondContact O-CD 3.37Å; V244-K269 WeakPolarHBondContact O-CE 3.33Å; V244-K269 WeakPolarHBondContact O-CG 3.48Å; V247-K269 HydrophobicContact CG2-CD 4.14Å; C263-K269 HydrophobicContact CB-CB 4.08Å; C263-K269 PolarHBondContact O-N 2.74Å; C263-K269 VanDerWaalsContact O-N 3.13Å; H266-K269 PolarHBondContact O-NZ 3.01Å; G267-K269 PolarHBondContact O-N 3.35Å
270R97.5Very high97.5Very high75 Ų7537.9 Ų37.928%0.28321%0.214SC..EExtended strand (participates in β ladder)trans-62.4142168.4-75150.4159.5-121.2-21.3109.4D245 K246 V247 T492 E493D245-R270 PolarHBondContact O-N 3.43Å; K246-R270 CarbonylContact C-O 3.4Å; K246-R270 WeakPolarHBondContact CA-O 3.24Å; K246-R270 HydrophobicContact CB-CB 4.03Å; K246-R270 HydrophobicContact CG-CB 4.21Å; V247-R270 PolarHBondContact N-O 2.8Å; R270-T492 PolarHBondContact NH1-O 2.84Å; R270-T492 PolarHBondContact NH2-O 3.13Å; R270-E493 IonicContact CZ-OE1 3.66Å; R270-E493 IonicContact CZ-OE2 2.86Å; R270-E493 IonicContact NE-OE2 3.03Å; R270-E493 PolarHBondContact NE-OE2 2.88Å; R270-E493 IonicContact NH1-OE2 2.7Å; R270-E493 IonicContact NH2-OE1 3.71Å; R270-E493 PolarHBondContact NH2-OE1 3.41Å; R270-E493 IonicContact NH2-OE2 3.59Å; R270-E493 PolarHBondContact NH2-OE2 3.49Å
271L98Very high97.5Very high26 Ų2633 Ų3314%0.13619%0.19CC..EExtended strand (participates in β ladder)trans-135.6138.1-175.1-175.754.8000110V247 I259 M260 C263 L273 F479V247-L271 HydrophobicContact CB-CD1 3.96Å; V247-L271 HydrophobicContact CG1-CD1 4.18Å; V247-L271 WeakPolarHBondContact O-CA 3.39Å; V247-L271 WeakPolarHBondContact O-CD1 3.33Å; I259-L271 HydrophobicContact CG2-CD1 3.83Å; I259-L271 HydrophobicContact CG2-CD2 4.48Å; M260-L271 HydrophobicContact CB-CD2 3.76Å; M260-L271 HydrophobicContact CG-CD2 4Å; C263-L271 HydrophobicContact CB-CD2 4.41Å; L271-L273 HydrophobicContact CD1-CD2 3.6Å; L271-L273 HydrophobicContact CD1-CG 4.16Å; L271-L273 HydrophobicContact CD2-CD1 4.09Å; L271-L273 HydrophobicContact CD2-CD2 3.98Å; L271-L273 HydrophobicContact CD2-CG 4.01Å; L271-L273 HydrophobicContact CG-CD1 4.45Å; L271-L273 HydrophobicContact CG-CD2 3.84Å; L271-L273 HydrophobicContact CG-CG 3.84Å; L271-F479 HydrophobicContact CB-CE2 4.04Å; L271-F479 HydrophobicContact CB-CZ 4.06Å; L271-F479 HydrophobicContact CD2-CZ 3.84Å; L271-F479 HydrophobicContact CG-CE2 4.17Å; L271-F479 HydrophobicContact CG-CZ 3.84Å; L271-F479 VanDerWaalsContact O-CE2 3.28Å; L271-F479 WeakPolarHBondContact O-CE2 3.36Å
272S98.4Very high97.6Very high3 Ų329.4 Ų29.42%0.02117%0.168CC..EExtended strand (participates in β ladder)trans-127.7131.4161.654.50000108.1K246 V247 F249 F479K246-S272 PolarHBondContact NZ-OG 3.1Å; V247-S272 PolarHBondContact O-N 2.99Å; V247-S272 VanDerWaalsContact O-N 3.13Å; F249-S272 PolarHBondContact N-O 3.35Å; S272-F479 WeakPolarHBondContact CA-O 3.04Å
273L98.6Very high97.6Very high4 Ų428.9 Ų28.92%0.02116%0.164CC..EExtended strand (participates in β ladder)trans-121.5125-177.3-63.3-177.9000108.6F249 I259 L271 L275 G478 F479F249-L273 HydrophobicContact CB-CD2 3.91Å; F249-L273 HydrophobicContact CD1-CD2 3.99Å; F249-L273 HydrophobicContact CG-CD2 4.39Å; F249-L273 WeakPolarHBondContact O-CA 2.99Å; I259-L273 HydrophobicContact CG2-CD2 4.42Å; L271-L273 HydrophobicContact CD1-CD2 3.6Å; L271-L273 HydrophobicContact CD1-CG 4.16Å; L271-L273 HydrophobicContact CD2-CD1 4.09Å; L271-L273 HydrophobicContact CD2-CD2 3.98Å; L271-L273 HydrophobicContact CD2-CG 4.01Å; L271-L273 HydrophobicContact CG-CD1 4.45Å; L271-L273 HydrophobicContact CG-CD2 3.84Å; L271-L273 HydrophobicContact CG-CG 3.84Å; L273-L275 HydrophobicContact CB-CD1 4.1Å; L273-L275 HydrophobicContact CB-CD2 4.08Å; L273-L275 HydrophobicContact CB-CG 3.95Å; L273-L275 HydrophobicContact CD1-CD1 4.13Å; L273-G478 CarbonylContact O-C 3.41Å; L273-G478 WeakPolarHBondContact O-CA 3.29Å; L273-F479 HydrophobicContact CB-CE1 4.46Å; L273-F479 HydrophobicContact CD1-CD1 4.14Å; L273-F479 HydrophobicContact CD1-CE1 3.45Å; L273-F479 VanDerWaalsContact CD1-CE1 3.45Å; L273-F479 HydrophobicContact CD1-CZ 3.98Å; L273-F479 HydrophobicContact CG-CD1 4.47Å; L273-F479 HydrophobicContact CG-CE1 3.94Å; L273-F479 HydrophobicContact CG-CZ 4.12Å; L273-F479 PolarHBondContact N-O 3.36Å; L273-F479 PolarHBondContact O-N 3.16Å; L273-F479 VanDerWaalsContact O-N 3.07Å
274E98.6Very high97.6Very high7 Ų729 Ų293%0.03316%0.164CC..EExtended strand (participates in β ladder)trans-112.7106.7165.3-74.1-57.6141.600107.9F249 T250 G251 G472 E482F249-E274 PolarHBondContact O-N 2.94Å; T250-E274 WeakPolarHBondContact CA-O 3.42Å; T250-E274 HydrophobicContact CG2-CB 3.9Å; T250-E274 WeakPolarHBondContact CG2-O 3.29Å; T250-E274 WeakPolarHBondContact OG1-CB 3.37Å; G251-E274 PolarHBondContact N-O 3.1Å; G251-E274 VanDerWaalsContact N-O 3.12Å; E274-G472 VanDerWaalsContact CD-CA 3.43Å; E274-G472 WeakPolarHBondContact OE1-CA 2.83Å; E274-G472 WeakPolarHBondContact OE2-CA 3.19Å; E274-E482 HydrophobicContact CG-CG 3.88Å
275L98.5Very high97.6Very high10 Ų1028.8 Ų28.85%0.05216%0.159CC..  trans-112.2-176.2-169.4-50.9173.4000111F249 G251 T253 L273 M476 S477F249-L275 HydrophobicContact CD1-CD2 3.82Å; F249-L275 HydrophobicContact CE1-CD2 3.72Å; G251-L275 VanDerWaalsContact O-CA 3.29Å; G251-L275 WeakPolarHBondContact O-CA 3.45Å; T253-L275 HydrophobicContact CG2-CD1 4.37Å; L273-L275 HydrophobicContact CB-CD1 4.1Å; L273-L275 HydrophobicContact CB-CD2 4.08Å; L273-L275 HydrophobicContact CB-CG 3.95Å; L273-L275 HydrophobicContact CD1-CD1 4.13Å; L275-M476 WeakPolarHBondContact CD1-O 3.34Å; L275-S477 PolarHBondContact N-O 2.97Å
276G95.1Very high97.6Very high2 Ų224.4 Ų24.42%0.02114%0.14CC..  trans-61.8171.8-179.600000114.5G251 E405 Y431 S477G251-G276 PolarHBondContact O-N 3.43Å; G276-E405 WeakPolarHBondContact CA-OE1 3.47Å; G276-E405 WeakPolarHBondContact CA-OE2 3.28Å; G276-Y431 WeakPolarHBondContact O-CD1 3.47Å; G276-S477 WeakPolarHBondContact O-CB 3.46Å; G276-S477 PolarHBondContact O-OG 3.44Å
277G97.6Very high97.7Very high3 Ų321.6 Ų21.63%0.03113%0.128CC..  trans-138.5161.9-178.700000113.6C308 E405G277-C308 WeakPolarHBondContact CA-O 3.41Å; G277-C308 PolarHBondContact N-O 3.44Å; G277-E405 PolarHBondContact N-OE1 3.38Å; G277-E405 WeakPolarHBondContact O-CG 3.41Å
278K98.5Very high97.8Very high2 Ų223.2 Ų23.21%0.00912%0.123CC..  trans-133.259.1164.3-161.465.4177175.30109.4R313 V401 A402 E404 Y431K278-R313 HydrophobicContact CD-CG 4.29Å; K278-R313 HydrophobicContact CG-CG 3.92Å; K278-R313 PolarHBondContact O-NE 3.48Å; K278-R313 PolarHBondContact O-NH2 3.42Å; K278-V401 WeakPolarHBondContact CE-O 3.41Å; K278-V401 PolarHBondContact NZ-O 2.9Å; K278-A402 VanDerWaalsContact CE-C 3.45Å; K278-A402 WeakPolarHBondContact CE-O 3.28Å; K278-A402 VanDerWaalsContact CG-O 3.32Å; K278-A402 WeakPolarHBondContact CG-O 3.18Å; K278-E404 WeakPolarHBondContact CD-O 2.99Å; K278-E404 VanDerWaalsContact CE-O 3.23Å; K278-E404 WeakPolarHBondContact CE-O 3.18Å; K278-E404 PolarHBondContact NZ-O 3.47Å; K278-Y431 HydrophobicContact CB-CD2 3.51Å; K278-Y431 HydrophobicContact CB-CE2 4.25Å; K278-Y431 HydrophobicContact CB-CG 4.19Å
279S98.6Very high97.6Very high2 Ų217 Ų171%0.0149%0.091CC..  trans-64.5123.6-164.6-74.10000112.5R313 A434 Y462S279-R313 PolarHBondContact O-N 3.24Å; S279-A434 WeakPolarHBondContact CA-O 3.39Å; S279-A434 WeakPolarHBondContact CB-O 3.34Å; S279-A434 PolarHBondContact OG-N 2.93Å; S279-A434 PolarHBondContact OG-O 2.98Å; S279-Y462 WeakPolarHBondContact CB-OH 3.32Å
280P98.4Very high97.5Very high6 Ų620 Ų204%0.03911%0.108CC..EExtended strand (participates in β ladder)trans-73.4140.417431.1-33.2000110.4I282 R313 F315 A426 A434 A435 G436 I452P280-I282 HydrophobicContact CB-CG1 4.38Å; P280-R313 CarbonylContact C-O 3.5Å; P280-R313 WeakPolarHBondContact CA-O 3.35Å; P280-F315 HydrophobicContact CB-CD2 3.9Å; P280-F315 HydrophobicContact CB-CE2 3.72Å; P280-A426 HydrophobicContact CB-CB 3.97Å; P280-A426 HydrophobicContact CG-CB 4.16Å; P280-A434 WeakPolarHBondContact CD-O 3.32Å; P280-A435 HydrophobicContact CG-CB 3.75Å; P280-A435 CarbonylContact O-C 3.58Å; P280-A435 VanDerWaalsContact O-CA 3.24Å; P280-A435 WeakPolarHBondContact O-CA 3.35Å; P280-G436 PolarHBondContact O-N 2.95Å; P280-I452 HydrophobicContact CG-CG2 4.24Å
281N98.4Very high97.4Very high0 Ų020.8 Ų20.80%012%0.115CC..EExtended strand (participates in β ladder)trans-125.1110.5171.2-172.38.2000108.8A296 R313 V314 F315 F438 Y462N281-A296 WeakPolarHBondContact ND2-CA 3.29Å; N281-A296 WeakPolarHBondContact ND2-CB 3.41Å; N281-R313 PolarHBondContact N-O 2.89Å; N281-V314 CarbonylContact O-C 3.59Å; N281-V314 VanDerWaalsContact O-CA 3.29Å; N281-V314 WeakPolarHBondContact O-CA 3.04Å; N281-F315 PolarHBondContact O-N 3.4Å; N281-F438 WeakPolarHBondContact OD1-CD2 3.45Å; N281-F438 WeakPolarHBondContact OD1-CE2 3.42Å; N281-Y462 HydrophobicContact CB-CE2 3.84Å
282I98.5Very high97.3Very high0 Ų019.6 Ų19.60%011%0.109CC..EExtended strand (participates in β ladder)trans-108.4124.8-161.8-60.5170.7000109.7P280 F284 F315 F416 L422 A426 G436 V437 F438 V448 I452P280-I282 HydrophobicContact CB-CG1 4.38Å; I282-F284 HydrophobicContact CG2-CD2 4.16Å; I282-F284 HydrophobicContact CG2-CE2 3.65Å; I282-F284 HydrophobicContact CG2-CZ 4.13Å; I282-F315 CarbonylContact C-O 3.2Å; I282-F315 WeakPolarHBondContact CA-O 3.42Å; I282-F315 HydrophobicContact CG1-CB 4.33Å; I282-F315 HydrophobicContact CG1-CD2 4.44Å; I282-F416 HydrophobicContact CG2-CE1 4.3Å; I282-F416 HydrophobicContact CG2-CZ 4.41Å; I282-L422 HydrophobicContact CD1-CD1 4.07Å; I282-L422 HydrophobicContact CD1-CD2 4.4Å; I282-L422 HydrophobicContact CD1-CG 4.36Å; I282-L422 HydrophobicContact CG1-CD1 4.02Å; I282-L422 HydrophobicContact CG2-CD1 3.91Å; I282-L422 HydrophobicContact CG2-CD2 3.57Å; I282-L422 HydrophobicContact CG2-CG 4.3Å; I282-A426 HydrophobicContact CD1-CB 4.4Å; I282-G436 WeakPolarHBondContact CB-O 3.45Å; I282-G436 PolarHBondContact N-O 3.02Å; I282-V437 HydrophobicContact CB-CB 4.47Å; I282-V437 HydrophobicContact CB-CG2 4.43Å; I282-V437 HydrophobicContact CG2-CG2 4.35Å; I282-V437 CarbonylContact O-C 3.49Å; I282-V437 WeakPolarHBondContact O-CA 3.49Å; I282-F438 PolarHBondContact O-N 3.46Å; I282-V448 HydrophobicContact CD1-CG1 3.62Å; I282-I452 HydrophobicContact CD1-CD1 4.31Å; I282-I452 HydrophobicContact CD1-CG1 4.31Å
283I98.4Very high97.3Very high0 Ų019.5 Ų19.50%011%0.108CC..EExtended strand (participates in β ladder)trans-121.6108.9-174.8-41.7-62.1000109.7A287 A292 V314 F315 V316 E317 I320 F324 F438I283-A287 HydrophobicContact CG2-CB 4.5Å; I283-A292 HydrophobicContact CD1-CB 4.2Å; I283-A292 HydrophobicContact CG2-CB 3.79Å; I283-V314 HydrophobicContact CG1-CG1 4.07Å; I283-F315 PolarHBondContact N-O 3.06Å; I283-V316 HydrophobicContact CB-CG2 4.37Å; I283-V316 HydrophobicContact CG1-CG2 4.3Å; I283-E317 PolarHBondContact O-N 3.46Å; I283-I320 HydrophobicContact CG2-CD1 4.02Å; I283-F324 HydrophobicContact CB-CE2 4.43Å; I283-F324 HydrophobicContact CD1-CE2 4.43Å; I283-F324 HydrophobicContact CG1-CE2 3.82Å; I283-F324 HydrophobicContact CG1-CZ 4.25Å; I283-F324 HydrophobicContact CG2-CD2 4.3Å; I283-F324 HydrophobicContact CG2-CE2 4.21Å; I283-F438 HydrophobicContact CD1-CB 3.96Å; I283-F438 HydrophobicContact CD1-CD2 3.43Å; I283-F438 VanDerWaalsContact CD1-CD2 3.43Å; I283-F438 HydrophobicContact CD1-CE2 4.21Å; I283-F438 HydrophobicContact CD1-CG 3.85Å
284F98.2Very high97.2Very high6 Ų623.6 Ų23.63%0.02613%0.127CC..  trans-83.7155.6173.2-71.1-84.3000111.9I282 D286 A287 E317 F416 M419 L422 V437 F438 T439 K444 V448I282-F284 HydrophobicContact CG2-CD2 4.16Å; I282-F284 HydrophobicContact CG2-CE2 3.65Å; I282-F284 HydrophobicContact CG2-CZ 4.13Å; F284-D286 VanDerWaalsContact CB-OD1 3.25Å; F284-D286 WeakPolarHBondContact CB-OD1 3.38Å; F284-D286 PolarHBondContact O-N 2.86Å; F284-A287 WeakPolarHBondContact O-CB 3.09Å; F284-A287 PolarHBondContact O-N 3.44Å; F284-A287 VanDerWaalsContact O-N 3.1Å; F284-E317 WeakPolarHBondContact CA-OE2 3.32Å; F284-E317 WeakPolarHBondContact CD1-OE2 3.41Å; F284-F416 AromaticContact CD1-CE2 3.98Å; F284-F416 HydrophobicContact CD1-CE2 3.98Å; F284-F416 AromaticContact CD1-CZ 3.78Å; F284-F416 HydrophobicContact CD1-CZ 3.78Å; F284-F416 AromaticContact CE1-CE2 3.69Å; F284-F416 HydrophobicContact CE1-CE2 3.69Å; F284-F416 AromaticContact CE1-CZ 3.77Å; F284-F416 HydrophobicContact CE1-CZ 3.77Å; F284-F416 HydrophobicContact CG-CZ 4.31Å; F284-F416 HydrophobicContact CZ-CE2 4.41Å; F284-F416 HydrophobicContact CZ-CZ 4.29Å; F284-M419 HydrophobicContact CE1-CE 3.57Å; F284-M419 HydrophobicContact CE1-SD 4.25Å; F284-M419 HydrophobicContact CE2-CE 4.27Å; F284-M419 HydrophobicContact CZ-CE 3.28Å; F284-M419 HydrophobicContact CZ-SD 3.71Å; F284-L422 HydrophobicContact CE1-CD2 4.13Å; F284-L422 HydrophobicContact CE2-CD2 4.3Å; F284-L422 HydrophobicContact CZ-CD2 3.54Å; F284-V437 HydrophobicContact CD2-CG2 4.07Å; F284-V437 HydrophobicContact CE2-CG2 3.74Å; F284-F438 PolarHBondContact N-O 3.32Å; F284-T439 HydrophobicContact CD2-CG2 4.31Å; F284-K444 HydrophobicContact CD1-CD 3.89Å; F284-K444 HydrophobicContact CE1-CD 4.09Å; F284-K444 HydrophobicContact CG-CD 4.14Å; F284-V448 HydrophobicContact CE2-CG2 3.99Å; F284-V448 HydrophobicContact CZ-CG2 3.99Å
285A97.5Very high97.1Very high30 Ų3025.5 Ų25.525%0.24814%0.136CC..THydrogen-bonded Turntrans-63.2-25.8-179.300000113.6A287 E317 S319 I320A285-A287 VanDerWaalsContact C-N 3.33Å; A285-E317 HydrophobicContact CB-CB 4.25Å; A285-E317 HydrophobicContact CB-CG 4.21Å; A285-E317 WeakPolarHBondContact CB-OE2 3.19Å; A285-E317 PolarHBondContact N-OE2 3.29Å; A285-S319 WeakPolarHBondContact CB-OG 3.45Å; A285-I320 HydrophobicContact CB-CG1 4.32Å; A285-I320 HydrophobicContact CB-CG2 3.97Å
286D97.6Very high97.1Very high47 Ų4725 Ų2525%0.25113%0.133SC..THydrogen-bonded Turntrans-84.4-6.3178.370.9-70.9000113.6F284 T439 K440 D441 K444F284-D286 VanDerWaalsContact CB-OD1 3.25Å; F284-D286 WeakPolarHBondContact CB-OD1 3.38Å; F284-D286 PolarHBondContact O-N 2.86Å; D286-T439 VanDerWaalsContact CG-OG1 3.27Å; D286-T439 PolarHBondContact OD1-OG1 2.81Å; D286-T439 PolarHBondContact OD2-OG1 3.09Å; D286-K440 WeakPolarHBondContact O-CD 3.41Å; D286-K440 VanDerWaalsContact O-CE 3.25Å; D286-K440 WeakPolarHBondContact O-CE 3.08Å; D286-K440 WeakPolarHBondContact O-CG 3.46Å; D286-K440 WeakPolarHBondContact OD2-CA 3.47Å; D286-K440 PolarHBondContact OD2-N 3.18Å; D286-D441 PolarHBondContact OD2-N 3.49Å; D286-D441 VanDerWaalsContact OD2-N 3.08Å; D286-K444 IonicContact OD1-NZ 2.7Å; D286-K444 PolarHBondContact OD1-NZ 3.07Å
287A97.8Very high97.2Very high7 Ų725.4 Ų25.46%0.05814%0.135CC..SBendtrans-60.5161.417400000111.9I283 F284 A285 V289 A292 F438I283-A287 HydrophobicContact CG2-CB 4.5Å; F284-A287 WeakPolarHBondContact O-CB 3.09Å; F284-A287 PolarHBondContact O-N 3.44Å; F284-A287 VanDerWaalsContact O-N 3.1Å; A285-A287 VanDerWaalsContact C-N 3.33Å; A287-V289 VanDerWaalsContact C-N 3.34Å; A287-V289 PolarHBondContact O-N 3.15Å; A287-A292 HydrophobicContact CB-CB 4.33Å; A287-F438 HydrophobicContact CB-CB 4.07Å
288D95.5Very high97.1Very high91 Ų9127.5 Ų27.549%0.48715%0.152SC..  trans-68.399.3158.3-170-36.7000107.9D290 E291 A292D288-D290 VanDerWaalsContact C-N 3.29Å; D288-D290 PolarHBondContact O-N 3.29Å; D288-D290 PolarHBondContact OD1-N 3.1Å; D288-E291 HydrophobicContact CB-CB 4.09Å; D288-E291 PolarHBondContact O-N 3.15Å; D288-E291 PolarHBondContact OD1-N 3.42Å; D288-A292 WeakPolarHBondContact O-CB 3.46Å; D288-A292 PolarHBondContact O-N 3.21Å
289V93.1Very high97.1Very high18 Ų1827.5 Ų27.511%0.10915%0.152CC..Hα-helixtrans-61.2-39-169.9177.30000111.5A287 A292 I293 I320 K323A287-V289 VanDerWaalsContact C-N 3.34Å; A287-V289 PolarHBondContact O-N 3.15Å; V289-A292 PolarHBondContact O-N 3.45Å; V289-I293 HydrophobicContact CG1-CD1 3.75Å; V289-I293 HydrophobicContact CG1-CG1 4.42Å; V289-I293 VanDerWaalsContact O-CD1 3.27Å; V289-I293 WeakPolarHBondContact O-CD1 3.44Å; V289-I293 WeakPolarHBondContact O-CG1 3.44Å; V289-I293 PolarHBondContact O-N 3.01Å; V289-I320 HydrophobicContact CG2-CD1 4.09Å; V289-I320 HydrophobicContact CG2-CG2 4.33Å; V289-K323 HydrophobicContact CG1-CD 4.23Å
290D93.9Very high97.1Very high82 Ų8227.5 Ų27.544%0.43915%0.152SC..Hα-helixtrans-72-43.1-175.7-63-19.6000110.3D288 I293 H294 K323D288-D290 VanDerWaalsContact C-N 3.29Å; D288-D290 PolarHBondContact O-N 3.29Å; D288-D290 PolarHBondContact OD1-N 3.1Å; D290-I293 PolarHBondContact O-N 3.41Å; D290-H294 PolarHBondContact O-CD2 2.79Å; D290-H294 PolarHBondContact O-N 2.94Å; D290-H294 VanDerWaalsContact O-N 3.12Å; D290-K323 IonicContact OD1-NZ 3.17Å; D290-K323 PolarHBondContact OD1-NZ 3.32Å; D290-K323 VanDerWaalsContact OD1-NZ 3.15Å
291E95.6Very high97.1Very high90 Ų9027.2 Ų27.242%0.42115%0.15SC..Hα-helixtrans-64-42.5172.8-179.957.6-156.400111.9D288 I293 H294 Q295D288-E291 HydrophobicContact CB-CB 4.09Å; D288-E291 PolarHBondContact O-N 3.15Å; D288-E291 PolarHBondContact OD1-N 3.42Å; E291-I293 VanDerWaalsContact C-N 3.3Å; E291-I293 PolarHBondContact O-N 3.08Å; E291-H294 PolarHBondContact O-N 3.17Å; E291-H294 VanDerWaalsContact O-N 3.14Å; E291-Q295 HydrophobicContact CG-CG 4.29Å; E291-Q295 WeakPolarHBondContact O-CB 3.38Å; E291-Q295 WeakPolarHBondContact O-CG 3.32Å; E291-Q295 PolarHBondContact O-N 2.78Å; E291-Q295 VanDerWaalsContact OE1-CG 3.24Å; E291-Q295 WeakPolarHBondContact OE1-CG 3.29Å; E291-Q295 PolarHBondContact OE1-NE2 2.9Å
292A97.1Very high97Very high1 Ų128.7 Ų28.71%0.00816%0.157CC..Hα-helixtrans-61.9-37.717900000112.1I283 A287 D288 V289 A296 F438I283-A292 HydrophobicContact CD1-CB 4.2Å; I283-A292 HydrophobicContact CG2-CB 3.79Å; A287-A292 HydrophobicContact CB-CB 4.33Å; D288-A292 WeakPolarHBondContact O-CB 3.46Å; D288-A292 PolarHBondContact O-N 3.21Å; V289-A292 PolarHBondContact O-N 3.45Å; A292-A296 WeakPolarHBondContact O-CB 3.41Å; A292-A296 PolarHBondContact O-N 2.73Å; A292-F438 HydrophobicContact CB-CB 4.04Å; A292-F438 HydrophobicContact CB-CD1 3.99Å; A292-F438 HydrophobicContact CB-CG 4.08Å
293I97.3Very high96.9Very high1 Ų128.7 Ų28.71%0.00516%0.157CC..Hα-helixtrans-64.5-47.7172.8-67.5157.8000110.3V289 D290 E291 Q295 A296 H297 F324 R327 L331V289-I293 HydrophobicContact CG1-CD1 3.75Å; V289-I293 HydrophobicContact CG1-CG1 4.42Å; V289-I293 VanDerWaalsContact O-CD1 3.27Å; V289-I293 WeakPolarHBondContact O-CD1 3.44Å; V289-I293 WeakPolarHBondContact O-CG1 3.44Å; V289-I293 PolarHBondContact O-N 3.01Å; D290-I293 PolarHBondContact O-N 3.41Å; E291-I293 VanDerWaalsContact C-N 3.3Å; E291-I293 PolarHBondContact O-N 3.08Å; I293-Q295 VanDerWaalsContact C-N 3.33Å; I293-Q295 PolarHBondContact O-N 3.15Å; I293-A296 PolarHBondContact O-N 2.72Å; I293-H297 PolarHBondContact O-CD2 3.18Å; I293-H297 PolarHBondContact O-N 2.92Å; I293-F324 HydrophobicContact CB-CD2 4.49Å; I293-F324 HydrophobicContact CB-CE2 4.15Å; I293-F324 HydrophobicContact CD1-CD2 4.12Å; I293-F324 HydrophobicContact CG1-CD2 3.28Å; I293-F324 HydrophobicContact CG1-CE2 3.37Å; I293-F324 HydrophobicContact CG1-CG 3.98Å; I293-F324 HydrophobicContact CG1-CZ 4.13Å; I293-R327 HydrophobicContact CD1-CB 3.86Å; I293-R327 HydrophobicContact CD1-CG 3.81Å; I293-R327 HydrophobicContact CG2-CG 4.11Å; I293-L331 HydrophobicContact CG2-CD1 3.55Å
294H96.5Very high96.9Very high90 Ų9028.7 Ų28.742%0.41716%0.157SC..Hα-helixtrans-59.1-43.6178.3-79.8-64.6000112.3D290 E291 H297 A298D290-H294 PolarHBondContact O-CD2 2.79Å; D290-H294 PolarHBondContact O-N 2.94Å; D290-H294 VanDerWaalsContact O-N 3.12Å; E291-H294 PolarHBondContact O-N 3.17Å; E291-H294 VanDerWaalsContact O-N 3.14Å; H294-H297 PolarHBondContact O-N 3.05Å; H294-A298 PolarHBondContact O-N 2.97Å
295Q97.1Very high96.9Very high47 Ų4728.4 Ų28.422%0.2216%0.156CC..Hα-helixtrans-67.1-37.3176.6-69-72.9-19.500112.5E291 I293 H297 A298 G299 F438E291-Q295 HydrophobicContact CG-CG 4.29Å; E291-Q295 WeakPolarHBondContact O-CB 3.38Å; E291-Q295 WeakPolarHBondContact O-CG 3.32Å; E291-Q295 PolarHBondContact O-N 2.78Å; E291-Q295 VanDerWaalsContact OE1-CG 3.24Å; E291-Q295 WeakPolarHBondContact OE1-CG 3.29Å; E291-Q295 PolarHBondContact OE1-NE2 2.9Å; I293-Q295 VanDerWaalsContact C-N 3.33Å; I293-Q295 PolarHBondContact O-N 3.15Å; Q295-H297 VanDerWaalsContact C-N 3.34Å; Q295-H297 PolarHBondContact O-N 3.46Å; Q295-A298 PolarHBondContact O-N 3.04Å; Q295-G299 PolarHBondContact O-N 3.05Å; Q295-F438 HydrophobicContact CB-CE1 3.51Å; Q295-F438 HydrophobicContact CB-CE2 4.46Å; Q295-F438 HydrophobicContact CB-CZ 3.43Å; Q295-F438 VanDerWaalsContact CB-CZ 3.43Å; Q295-F438 HydrophobicContact CG-CE1 3.75Å; Q295-F438 HydrophobicContact CG-CZ 4.08Å
296A98Very high97Very high0 Ų027 Ų270%014%0.144CC..Hα-helixtrans-64.7-38.6173.800000112.4N281 A292 I293 G299 L300 F324 M411N281-A296 WeakPolarHBondContact ND2-CA 3.29Å; N281-A296 WeakPolarHBondContact ND2-CB 3.41Å; A292-A296 WeakPolarHBondContact O-CB 3.41Å; A292-A296 PolarHBondContact O-N 2.73Å; I293-A296 PolarHBondContact O-N 2.72Å; A296-G299 PolarHBondContact O-N 2.96Å; A296-L300 PolarHBondContact O-N 3.28Å; A296-F324 HydrophobicContact CB-CE2 4.48Å; A296-F324 HydrophobicContact CB-CZ 3.81Å; A296-M411 HydrophobicContact CB-CE 4.49Å
297H97.9Very high97Very high10 Ų1025.1 Ų25.15%0.04613%0.134CC..Hα-helixtrans-65.7-44.3173.5-85.5-106.6000112.1I293 H294 Q295 L300 F301 S328I293-H297 PolarHBondContact O-CD2 3.18Å; I293-H297 PolarHBondContact O-N 2.92Å; H294-H297 PolarHBondContact O-N 3.05Å; Q295-H297 VanDerWaalsContact C-N 3.34Å; Q295-H297 PolarHBondContact O-N 3.46Å; H297-L300 PolarHBondContact O-N 3.23Å; H297-F301 HydrophobicContact CB-CD2 4.22Å; H297-F301 AromaticContact CE1-CE2 3.71Å; H297-F301 AromaticContact ND1-CD2 3.58Å; H297-F301 AromaticContact ND1-CE2 3.49Å; H297-F301 WeakPolarHBondContact ND1-CE2 3.2Å; H297-F301 WeakPolarHBondContact O-CB 3.38Å; H297-F301 PolarHBondContact O-N 3.28Å; H297-S328 PolarHBondContact CE1-O 2.8Å; H297-S328 VanDerWaalsContact NE2-CA 3.27Å; H297-S328 WeakPolarHBondContact NE2-CA 3.48Å; H297-S328 WeakPolarHBondContact NE2-CB 3.44Å; H297-S328 PolarHBondContact NE2-O 2.79Å; H297-S328 PolarHBondContact NE2-OG 3.33Å
298A96.2Very high97Very high48 Ų4826.2 Ų26.240%0.39714%0.141SC..Hα-helixtrans-63.2-42.6174.600000111.6H294 Q295 L300 F302H294-A298 PolarHBondContact O-N 2.97Å; Q295-A298 PolarHBondContact O-N 3.04Å; A298-L300 PolarHBondContact O-N 2.65Å; A298-F302 WeakPolarHBondContact O-CB 3.28Å; A298-F302 PolarHBondContact O-N 2.74Å
299G97.3Very high97.1Very high1 Ų121.9 Ų21.91%0.0112%0.117CC..Hα-helixtrans-62.5-23.2-17900000114.5Q295 A296 A310 G311 Y462 N463Q295-G299 PolarHBondContact O-N 3.05Å; A296-G299 PolarHBondContact O-N 2.96Å; G299-A310 WeakPolarHBondContact O-CA 3.29Å; G299-G311 PolarHBondContact O-N 2.82Å; G299-Y462 VanDerWaalsContact CA-CD1 3.42Å; G299-N463 PolarHBondContact O-ND2 3.44Å
300L98.4Very high97.4Very high2 Ų221.4 Ų21.41%0.0112%0.115CC..Hα-helixtrans-110.7-53.5178.3175.465000113.8A296 H297 A298 F302 G305 A310 M411A296-L300 PolarHBondContact O-N 3.28Å; H297-L300 PolarHBondContact O-N 3.23Å; A298-L300 PolarHBondContact O-N 2.65Å; L300-F302 PolarHBondContact O-N 2.94Å; L300-G305 WeakPolarHBondContact O-CA 3.44Å; L300-G305 PolarHBondContact O-N 3.12Å; L300-A310 HydrophobicContact CD1-CB 4.02Å; L300-M411 HydrophobicContact CB-CE 4.39Å; L300-M411 HydrophobicContact CD2-CB 3.3Å; L300-M411 HydrophobicContact CD2-CE 3.95Å; L300-M411 HydrophobicContact CD2-CG 3.73Å
301F98.3Very high97.6Very high0 Ų017.5 Ų17.50%010%0.095CC..Hα-helixtrans-79-7.2-171.4-63.8-68.8000113.3H297 Q304 A332 R335 P389 V391 P409 M411H297-F301 HydrophobicContact CB-CD2 4.22Å; H297-F301 AromaticContact CE1-CE2 3.71Å; H297-F301 AromaticContact ND1-CD2 3.58Å; H297-F301 AromaticContact ND1-CE2 3.49Å; H297-F301 WeakPolarHBondContact ND1-CE2 3.2Å; H297-F301 WeakPolarHBondContact O-CB 3.38Å; H297-F301 PolarHBondContact O-N 3.28Å; F301-Q304 PolarHBondContact O-N 2.92Å; F301-A332 HydrophobicContact CE2-CB 4.5Å; F301-A332 HydrophobicContact CZ-CB 4.35Å; F301-R335 PolarHBondContact O-NH2 2.81Å; F301-P389 HydrophobicContact CD1-CB 3.99Å; F301-P389 HydrophobicContact CE1-CB 3.59Å; F301-P389 HydrophobicContact CZ-CB 4.06Å; F301-V391 HydrophobicContact CZ-CG2 4.31Å; F301-P409 HydrophobicContact CD1-CB 3.76Å; F301-P409 HydrophobicContact CE1-CB 4.06Å; F301-P409 WeakPolarHBondContact CE1-O 3.32Å; F301-M411 HydrophobicContact CD2-CE 4.45Å; F301-M411 HydrophobicContact CE2-CE 3.83Å; F301-M411 HydrophobicContact CZ-CB 4.22Å
302F96.8Very high97.7Very high32 Ų3213.8 Ų13.814%0.148%0.079CC..G310 helixtrans-57.9138.7167.8177.5-111.8000110.9H95 I99 F149 A298 L300 Q304 G305 V307H95-F302 HydrophobicContact CB-CE2 4.01Å; H95-F302 AromaticContact CD2-CE2 3.95Å; H95-F302 AromaticContact CE1-CD2 3.94Å; H95-F302 AromaticContact CG-CE2 3.64Å; H95-F302 AromaticContact ND1-CD2 3.96Å; H95-F302 AromaticContact ND1-CE2 3.7Å; I99-F302 HydrophobicContact CD1-CE2 3.49Å; I99-F302 VanDerWaalsContact CD1-CE2 3.49Å; I99-F302 HydrophobicContact CD1-CZ 3.78Å; I99-F302 HydrophobicContact CG2-CZ 4.16Å; F149-F302 AromaticContact CE1-CE1 3.74Å; F149-F302 HydrophobicContact CE1-CE1 3.74Å; F149-F302 HydrophobicContact CE1-CZ 4.05Å; F149-F302 HydrophobicContact CZ-CD1 4.32Å; F149-F302 AromaticContact CZ-CE1 3.6Å; F149-F302 HydrophobicContact CZ-CE1 3.6Å; F149-F302 HydrophobicContact CZ-CZ 4.33Å; A298-F302 WeakPolarHBondContact O-CB 3.28Å; A298-F302 PolarHBondContact O-N 2.74Å; L300-F302 PolarHBondContact O-N 2.94Å; F302-Q304 PolarHBondContact O-N 3.09Å; F302-Q304 VanDerWaalsContact O-N 3.1Å; F302-G305 PolarHBondContact O-N 3.49Å; F302-V307 HydrophobicContact CD1-CG2 3.98Å; F302-V307 WeakPolarHBondContact O-CG2 3.33Å
303N97.6Very high97.8Very high0 Ų013.8 Ų13.80%08%0.079CC..G310 helixtrans48.536.2-175.3-157.345.5000113.5K91 N148 F149 G305 Q306 V307K91-N303 WeakPolarHBondContact CB-OD1 3.3Å; K91-N303 WeakPolarHBondContact CE-OD1 3.48Å; N148-N303 PolarHBondContact O-ND2 2.77Å; F149-N303 HydrophobicContact CE1-CB 4.4Å; F149-N303 HydrophobicContact CE2-CB 4.45Å; F149-N303 WeakPolarHBondContact CE2-ND2 3.19Å; F149-N303 HydrophobicContact CZ-CB 3.75Å; F149-N303 WeakPolarHBondContact CZ-ND2 3.5Å; N303-G305 PolarHBondContact O-N 2.81Å; N303-G305 VanDerWaalsContact O-N 3.15Å; N303-Q306 PolarHBondContact ND2-O 3.24Å; N303-Q306 VanDerWaalsContact O-CB 3.26Å; N303-Q306 WeakPolarHBondContact O-CB 3.47Å; N303-Q306 PolarHBondContact O-N 3.17Å; N303-Q306 PolarHBondContact O-NE2 2.79Å; N303-V307 HydrophobicContact CB-CG2 3.74Å
304Q98Very high97.8Very high0 Ų013.8 Ų13.80%08%0.078CC..G310 helixtrans60.622.2-179.1-64.976.4-6200113.7G90 F301 F302 Q306 Q347 G348 P349 G408 P409G90-Q304 PolarHBondContact O-NE2 3.14Å; G90-Q304 VanDerWaalsContact O-NE2 3.11Å; F301-Q304 PolarHBondContact O-N 2.92Å; F302-Q304 PolarHBondContact O-N 3.09Å; F302-Q304 VanDerWaalsContact O-N 3.1Å; Q304-Q306 HydrophobicContact CB-CG 4.35Å; Q304-Q306 PolarHBondContact O-N 3.19Å; Q304-Q347 HydrophobicContact CB-CG 4.46Å; Q304-Q347 HydrophobicContact CG-CG 3.65Å; Q304-G348 VanDerWaalsContact CD-N 3.34Å; Q304-G348 WeakPolarHBondContact CG-O 3.43Å; Q304-G348 PolarHBondContact NE2-O 3.4Å; Q304-P349 WeakPolarHBondContact CG-O 3.36Å; Q304-P349 PolarHBondContact NE2-O 3.19Å; Q304-G408 CarbonylContact O-C 3.55Å; Q304-G408 WeakPolarHBondContact O-CA 3.24Å; Q304-P409 WeakPolarHBondContact O-CD 3.49Å
305G98.2Very high97.9Very high0 Ų09.5 Ų9.50%06%0.059CC..G310 helixtrans75.57.3-172.600000114.8L300 F302 N303 V307 F407 G408L300-G305 WeakPolarHBondContact O-CA 3.44Å; L300-G305 PolarHBondContact O-N 3.12Å; F302-G305 PolarHBondContact O-N 3.49Å; N303-G305 PolarHBondContact O-N 2.81Å; N303-G305 VanDerWaalsContact O-N 3.15Å; G305-V307 PolarHBondContact O-N 2.91Å; G305-F407 CarbonylContact O-C 3.51Å; G305-F407 VanDerWaalsContact O-C 3.22Å; G305-F407 WeakPolarHBondContact O-CA 3.4Å; G305-G408 PolarHBondContact O-N 3.47Å
306Q98.7Very high98Very high0 Ų07.3 Ų7.30%05%0.048CC..  trans-84.257.1175.3-54.1174.5120.400109.8W147 N148 N303 Q304 H355 F407W147-Q306 HydrophobicContact CH2-CB 3.86Å; W147-Q306 HydrophobicContact CH2-CG 3.86Å; W147-Q306 HydrophobicContact CZ3-CB 3.69Å; W147-Q306 VanDerWaalsContact CZ3-CD 3.42Å; W147-Q306 HydrophobicContact CZ3-CG 3.88Å; N148-Q306 HydrophobicContact CB-CB 4.33Å; N148-Q306 WeakPolarHBondContact CB-O 3.44Å; N148-Q306 PolarHBondContact ND2-O 3.41Å; N303-Q306 PolarHBondContact ND2-O 3.24Å; N303-Q306 VanDerWaalsContact O-CB 3.26Å; N303-Q306 WeakPolarHBondContact O-CB 3.47Å; N303-Q306 PolarHBondContact O-N 3.17Å; N303-Q306 PolarHBondContact O-NE2 2.79Å; Q304-Q306 HydrophobicContact CB-CG 4.35Å; Q304-Q306 PolarHBondContact O-N 3.19Å; Q306-H355 PolarHBondContact OE1-CD2 2.95Å; Q306-F407 HydrophobicContact CB-CD1 3.97Å; Q306-F407 HydrophobicContact CB-CE1 3.81Å; Q306-F407 HydrophobicContact CG-CD1 4.36Å
307V98.3Very high98Very high8 Ų89.5 Ų9.55%0.0486%0.059CC..  trans-134.6128.1-176.3-167.10000108.2F149 F302 N303 G305 T309 A310 F407F149-V307 HydrophobicContact CE2-CB 4.35Å; F149-V307 HydrophobicContact CE2-CG1 4.1Å; F149-V307 HydrophobicContact CE2-CG2 3.99Å; F149-V307 HydrophobicContact CZ-CG1 4.38Å; F149-V307 HydrophobicContact CZ-CG2 3.93Å; F302-V307 HydrophobicContact CD1-CG2 3.98Å; F302-V307 WeakPolarHBondContact O-CG2 3.33Å; N303-V307 HydrophobicContact CB-CG2 3.74Å; G305-V307 PolarHBondContact O-N 2.91Å; V307-T309 WeakPolarHBondContact CG1-OG1 3.36Å; V307-T309 PolarHBondContact O-N 3.36Å; V307-A310 HydrophobicContact CB-CB 4.24Å; V307-A310 WeakPolarHBondContact O-CB 3.3Å; V307-A310 PolarHBondContact O-N 2.64Å; V307-F407 VanDerWaalsContact C-CE2 3.4Å
308C97.4Very high97.9Very high29 Ų2910.8 Ų10.820%0.1967%0.071CC..THydrogen-bonded Turntrans-61.1-29.7-179.552.70000112.6G277 F407 L433G277-C308 WeakPolarHBondContact CA-O 3.41Å; G277-C308 PolarHBondContact N-O 3.44Å; C308-F407 HydrophobicContact CB-CE2 4.42Å; C308-L433 HydrophobicContact CB-CD2 3.5Å; C308-L433 VanDerWaalsContact CB-CD2 3.5Å; C308-L433 WeakPolarHBondContact O-CD2 3.24Å
309T98.1Very high97.9Very high0 Ų012.9 Ų12.90%08%0.083CC..THydrogen-bonded Turntrans-90.87.9176.557.70000113.9V307 G311 L433 A434 W458 Y462 N463 F465 F471V307-T309 WeakPolarHBondContact CG1-OG1 3.36Å; V307-T309 PolarHBondContact O-N 3.36Å; T309-G311 PolarHBondContact O-N 3.16Å; T309-L433 HydrophobicContact CG2-CD2 3.84Å; T309-L433 HydrophobicContact CG2-CG 4.12Å; T309-A434 HydrophobicContact CG2-CB 3.68Å; T309-W458 HydrophobicContact CG2-CH2 3.98Å; T309-Y462 VanDerWaalsContact O-CE1 3.31Å; T309-Y462 WeakPolarHBondContact O-CE1 3.46Å; T309-Y462 PolarHBondContact O-OH 3.24Å; T309-N463 PolarHBondContact OG1-OD1 2.77Å; T309-F465 HydrophobicContact CG2-CZ 3.98Å; T309-F471 HydrophobicContact CG2-CE2 3.61Å; T309-F471 HydrophobicContact CG2-CZ 3.43Å; T309-F471 VanDerWaalsContact CG2-CZ 3.43Å
310A98.3Very high97.9Very high8 Ų814 Ų147%0.0669%0.088CC..  trans-51.4125.6-174.500000111.6G299 L300 V307 S312G299-A310 WeakPolarHBondContact O-CA 3.29Å; L300-A310 HydrophobicContact CD1-CB 4.02Å; V307-A310 HydrophobicContact CB-CB 4.24Å; V307-A310 WeakPolarHBondContact O-CB 3.3Å; V307-A310 PolarHBondContact O-N 2.64Å; A310-S312 PolarHBondContact O-N 2.87Å; A310-S312 PolarHBondContact O-OG 2.7Å
311G98.1Very high97.9Very high0 Ų014 Ų140%09%0.088CC..  trans-71.356.8179.300000112.8G299 T309 Y462G299-G311 PolarHBondContact O-N 2.82Å; T309-G311 PolarHBondContact O-N 3.16Å; G311-Y462 WeakPolarHBondContact CA-OH 3.4Å; G311-Y462 PolarHBondContact N-OH 2.74Å
312S98Very high97.9Very high13 Ų1319.1 Ų19.19%0.09112%0.115CC..  trans-74.6-27.5-168.951.70000113A310 Q412A310-S312 PolarHBondContact O-N 2.87Å; A310-S312 PolarHBondContact O-OG 2.7Å; S312-Q412 WeakPolarHBondContact O-CB 3.29Å; S312-Q412 PolarHBondContact O-N 3.25Å; S312-Q412 PolarHBondContact O-OE1 3.22Å
313R98.4Very high97.9Very high1 Ų122.8 Ų22.80%0.00413%0.131CC..EExtended strand (participates in β ladder)trans-101.399.2172.4-65-167.1-67.2156.63.9110.6K278 S279 P280 N281 F315 A402 M414 K425 A426K278-R313 HydrophobicContact CD-CG 4.29Å; K278-R313 HydrophobicContact CG-CG 3.92Å; K278-R313 PolarHBondContact O-NE 3.48Å; K278-R313 PolarHBondContact O-NH2 3.42Å; S279-R313 PolarHBondContact O-N 3.24Å; P280-R313 CarbonylContact C-O 3.5Å; P280-R313 WeakPolarHBondContact CA-O 3.35Å; N281-R313 PolarHBondContact N-O 2.89Å; R313-F315 HydrophobicContact CB-CD2 4.4Å; R313-F315 HydrophobicContact CB-CE2 3.76Å; R313-F315 HydrophobicContact CB-CZ 4.41Å; R313-A402 VanDerWaalsContact CD-O 3.29Å; R313-A402 WeakPolarHBondContact CD-O 3.48Å; R313-M414 HydrophobicContact CB-CE 4.07Å; R313-M414 HydrophobicContact CB-SD 4.4Å; R313-M414 HydrophobicContact CG-CE 3.67Å; R313-K425 PolarHBondContact NH1-O 3.08Å; R313-A426 PolarHBondContact NH2-O 2.85Å
314V98.6Very high97.9Very high0 Ų022.8 Ų22.80%013%0.131CC..EExtended strand (participates in β ladder)trans-93.4112.1178.1-170.90000109.1N281 I283 V316 F324 M411 Q412 I413 M414N281-V314 CarbonylContact O-C 3.59Å; N281-V314 VanDerWaalsContact O-CA 3.29Å; N281-V314 WeakPolarHBondContact O-CA 3.04Å; I283-V314 HydrophobicContact CG1-CG1 4.07Å; V314-V316 HydrophobicContact CG1-CG2 3.83Å; V314-F324 HydrophobicContact CG1-CE1 3.73Å; V314-F324 HydrophobicContact CG1-CZ 3.62Å; V314-M411 HydrophobicContact CG2-CE 4.25Å; V314-M411 HydrophobicContact CG2-CG 3.85Å; V314-M411 HydrophobicContact CG2-SD 4.13Å; V314-Q412 PolarHBondContact N-O 2.82Å; V314-I413 CarbonylContact O-C 3.55Å; V314-I413 WeakPolarHBondContact O-CA 3.42Å; V314-M414 PolarHBondContact O-N 3.34Å
315F98.5Very high98Very high1 Ų123.3 Ų23.30%0.00413%0.134CC..EExtended strand (participates in β ladder)trans-96.4121.1175.6-67.7-88.2000108.9P280 N281 I282 I283 R313 M414 F416 L422 K425 A426P280-F315 HydrophobicContact CB-CD2 3.9Å; P280-F315 HydrophobicContact CB-CE2 3.72Å; N281-F315 PolarHBondContact O-N 3.4Å; I282-F315 CarbonylContact C-O 3.2Å; I282-F315 WeakPolarHBondContact CA-O 3.42Å; I282-F315 HydrophobicContact CG1-CB 4.33Å; I282-F315 HydrophobicContact CG1-CD2 4.44Å; I283-F315 PolarHBondContact N-O 3.06Å; R313-F315 HydrophobicContact CB-CD2 4.4Å; R313-F315 HydrophobicContact CB-CE2 3.76Å; R313-F315 HydrophobicContact CB-CZ 4.41Å; F315-M414 WeakPolarHBondContact CA-O 3.43Å; F315-M414 HydrophobicContact CD1-CB 3.82Å; F315-M414 HydrophobicContact CD1-SD 4.12Å; F315-M414 HydrophobicContact CE1-CB 3.99Å; F315-M414 HydrophobicContact CE1-CG 4.34Å; F315-M414 HydrophobicContact CE1-SD 3.4Å; F315-M414 WeakPolarHBondContact CE1-SD 3.03Å; F315-M414 HydrophobicContact CE2-SD 4.14Å; F315-M414 HydrophobicContact CG-CB 4.5Å; F315-M414 HydrophobicContact CZ-SD 3.42Å; F315-M414 WeakPolarHBondContact CZ-SD 3.36Å; F315-F416 HydrophobicContact CB-CD1 3.88Å; F315-F416 HydrophobicContact CB-CE1 4.28Å; F315-L422 HydrophobicContact CB-CD1 3.71Å; F315-L422 HydrophobicContact CD1-CD1 4.23Å; F315-L422 HydrophobicContact CG-CD1 3.97Å; F315-K425 HydrophobicContact CE1-CB 3.86Å; F315-K425 HydrophobicContact CZ-CB 4.31Å; F315-A426 HydrophobicContact CE2-CB 4.36Å
316V98.4Very high97.9Very high0 Ų028.5 Ų28.50%016%0.162CC..EExtended strand (participates in β ladder)trans-122134-176.2-1740000110.2I283 V314 I320 Y321 F324 I413 M414 R415 F416I283-V316 HydrophobicContact CB-CG2 4.37Å; I283-V316 HydrophobicContact CG1-CG2 4.3Å; V314-V316 HydrophobicContact CG1-CG2 3.83Å; V316-I320 HydrophobicContact CG1-CD1 3.92Å; V316-I320 HydrophobicContact CG1-CG1 3.77Å; V316-Y321 HydrophobicContact CB-CD2 4.17Å; V316-F324 HydrophobicContact CG1-CB 3.85Å; V316-F324 HydrophobicContact CG1-CD2 4.29Å; V316-F324 HydrophobicContact CG1-CG 4.02Å; V316-F324 HydrophobicContact CG2-CB 4.37Å; V316-F324 HydrophobicContact CG2-CD1 3.65Å; V316-F324 HydrophobicContact CG2-CD2 4.09Å; V316-F324 HydrophobicContact CG2-CE1 3.93Å; V316-F324 HydrophobicContact CG2-CE2 4.34Å; V316-F324 HydrophobicContact CG2-CG 3.76Å; V316-F324 HydrophobicContact CG2-CZ 4.28Å; V316-I413 HydrophobicContact CG2-CG2 3.92Å; V316-M414 PolarHBondContact N-O 3.02Å; V316-R415 WeakPolarHBondContact O-CA 3.43Å; V316-F416 WeakPolarHBondContact O-CD1 3.12Å; V316-F416 PolarHBondContact O-N 2.93Å; V316-F416 VanDerWaalsContact O-N 3.08Å
317E97.8Very high97.9Very high46 Ų4632.8 Ų32.822%0.21518%0.178CC..EExtended strand (participates in β ladder)trans-63135.9178.2-166.8174.9160.100110.5I283 F284 A285 S319 I320 Y321 F416I283-E317 PolarHBondContact O-N 3.46Å; F284-E317 WeakPolarHBondContact CA-OE2 3.32Å; F284-E317 WeakPolarHBondContact CD1-OE2 3.41Å; A285-E317 HydrophobicContact CB-CB 4.25Å; A285-E317 HydrophobicContact CB-CG 4.21Å; A285-E317 WeakPolarHBondContact CB-OE2 3.19Å; A285-E317 PolarHBondContact N-OE2 3.29Å; E317-S319 PolarHBondContact O-N 2.96Å; E317-I320 HydrophobicContact CB-CG1 4.41Å; E317-I320 WeakPolarHBondContact O-CG1 3.25Å; E317-I320 PolarHBondContact O-N 2.83Å; E317-Y321 PolarHBondContact O-N 2.92Å; E317-F416 HydrophobicContact CB-CE1 4.04Å; E317-F416 HydrophobicContact CB-CE2 3.95Å; E317-F416 HydrophobicContact CB-CZ 3.59Å; E317-F416 HydrophobicContact CG-CE2 4.02Å; E317-F416 HydrophobicContact CG-CZ 4.18Å
318A97Very high97.9Very high37 Ų3732.4 Ų32.431%0.30618%0.176SC..G310 helixtrans-50.8-37.4-169.800000114.8I320 Y321 R415 F416 D417A318-I320 VanDerWaalsContact C-N 3.26Å; A318-I320 PolarHBondContact O-N 3.23Å; A318-Y321 PolarHBondContact O-N 3.11Å; A318-R415 HydrophobicContact CB-CG 3.9Å; A318-F416 PolarHBondContact N-O 3.32Å; A318-D417 WeakPolarHBondContact CB-OD1 3.45Å
319S96.9Very high98Very high92 Ų9231.8 Ų31.864%0.64317%0.171SC*.G310 helixtrans-67.8-20.2-176.657.60000114.7A285 E317A285-S319 WeakPolarHBondContact CB-OG 3.45Å; E317-S319 PolarHBondContact O-N 2.96Å
320I97.4Very high98Very high24 Ų2437 Ų3712%0.12320%0.195CC..G310 helixtrans-117.7317959.2155.9000113I283 A285 V289 V316 E317 A318 D322 K323 F324I283-I320 HydrophobicContact CG2-CD1 4.02Å; A285-I320 HydrophobicContact CB-CG1 4.32Å; A285-I320 HydrophobicContact CB-CG2 3.97Å; V289-I320 HydrophobicContact CG2-CD1 4.09Å; V289-I320 HydrophobicContact CG2-CG2 4.33Å; V316-I320 HydrophobicContact CG1-CD1 3.92Å; V316-I320 HydrophobicContact CG1-CG1 3.77Å; E317-I320 HydrophobicContact CB-CG1 4.41Å; E317-I320 WeakPolarHBondContact O-CG1 3.25Å; E317-I320 PolarHBondContact O-N 2.83Å; A318-I320 VanDerWaalsContact C-N 3.26Å; A318-I320 PolarHBondContact O-N 3.23Å; I320-D322 PolarHBondContact O-N 3Å; I320-K323 PolarHBondContact O-N 2.97Å; I320-F324 WeakPolarHBondContact O-CB 3.44Å; I320-F324 PolarHBondContact O-N 3.35Å
321Y98Very high97.9Very high4 Ų437.8 Ų37.82%0.01620%0.199CC..Hα-helixtrans-56.9-52.7-172.2180-90.2000113.1V316 E317 A318 K323 F324 V325 D394 I413 R415V316-Y321 HydrophobicContact CB-CD2 4.17Å; E317-Y321 PolarHBondContact O-N 2.92Å; A318-Y321 PolarHBondContact O-N 3.11Å; Y321-K323 PolarHBondContact O-N 3.32Å; Y321-F324 WeakPolarHBondContact O-CB 3.45Å; Y321-F324 PolarHBondContact O-N 3.15Å; Y321-F324 VanDerWaalsContact O-N 3.17Å; Y321-V325 HydrophobicContact CD1-CG2 4.05Å; Y321-V325 HydrophobicContact CE1-CG2 3.75Å; Y321-V325 HydrophobicContact CE2-CG2 4.25Å; Y321-V325 HydrophobicContact CG-CG2 4.47Å; Y321-V325 WeakPolarHBondContact O-CG2 3.24Å; Y321-V325 PolarHBondContact O-N 3.04Å; Y321-D394 WeakPolarHBondContact OH-CA 3.33Å; Y321-D394 PolarHBondContact OH-N 3.3Å; Y321-D394 PolarHBondContact OH-OD1 2.6Å; Y321-I413 HydrophobicContact CD2-CG2 4.39Å; Y321-I413 HydrophobicContact CE2-CG2 3.8Å; Y321-R415 HydrophobicContact CD2-CB 3.77Å; Y321-R415 HydrophobicContact CD2-CG 4.04Å; Y321-R415 HydrophobicContact CE2-CB 3.83Å; Y321-R415 HydrophobicContact CG-CB 4.49Å; Y321-R415 HydrophobicContact CG-CG 4.37Å
322D97.6Very high97.9Very high106 Ų10638 Ų3857%0.56720%0.2SC*.Hα-helixtrans-63.3-43.5-175.9-64.8-26.5000111.2I320 F324 V325 D326 R415I320-D322 PolarHBondContact O-N 3Å; D322-F324 VanDerWaalsContact C-N 3.33Å; D322-F324 PolarHBondContact O-N 3.17Å; D322-V325 PolarHBondContact O-N 3.5Å; D322-D326 PolarHBondContact O-N 2.9Å; D322-R415 IonicContact OD1-NH2 2.8Å
323K97.1Very high97.9Very high110 Ų11044.3 Ų44.348%0.47823%0.226SC..Hα-helixtrans-58.2-45.4174.6-176.2-174.2173.7-162.40111.3V289 D290 I320 Y321 R327V289-K323 HydrophobicContact CG1-CD 4.23Å; D290-K323 IonicContact OD1-NZ 3.17Å; D290-K323 PolarHBondContact OD1-NZ 3.32Å; D290-K323 VanDerWaalsContact OD1-NZ 3.15Å; I320-K323 PolarHBondContact O-N 2.97Å; Y321-K323 PolarHBondContact O-N 3.32Å; K323-R327 WeakPolarHBondContact O-CB 3.49Å; K323-R327 PolarHBondContact O-N 2.78Å
324F98.3Very high97.9Very high0 Ų047.9 Ų47.90%025%0.251CS..Hα-helixtrans-63-43.6179.7-172.7-78.3000111.6I283 I293 A296 V314 V316 I320 Y321 D322 S328 I413I283-F324 HydrophobicContact CB-CE2 4.43Å; I283-F324 HydrophobicContact CD1-CE2 4.43Å; I283-F324 HydrophobicContact CG1-CE2 3.82Å; I283-F324 HydrophobicContact CG1-CZ 4.25Å; I283-F324 HydrophobicContact CG2-CD2 4.3Å; I283-F324 HydrophobicContact CG2-CE2 4.21Å; I293-F324 HydrophobicContact CB-CD2 4.49Å; I293-F324 HydrophobicContact CB-CE2 4.15Å; I293-F324 HydrophobicContact CD1-CD2 4.12Å; I293-F324 HydrophobicContact CG1-CD2 3.28Å; I293-F324 HydrophobicContact CG1-CE2 3.37Å; I293-F324 HydrophobicContact CG1-CG 3.98Å; I293-F324 HydrophobicContact CG1-CZ 4.13Å; A296-F324 HydrophobicContact CB-CE2 4.48Å; A296-F324 HydrophobicContact CB-CZ 3.81Å; V314-F324 HydrophobicContact CG1-CE1 3.73Å; V314-F324 HydrophobicContact CG1-CZ 3.62Å; V316-F324 HydrophobicContact CG1-CB 3.85Å; V316-F324 HydrophobicContact CG1-CD2 4.29Å; V316-F324 HydrophobicContact CG1-CG 4.02Å; V316-F324 HydrophobicContact CG2-CB 4.37Å; V316-F324 HydrophobicContact CG2-CD1 3.65Å; V316-F324 HydrophobicContact CG2-CD2 4.09Å; V316-F324 HydrophobicContact CG2-CE1 3.93Å; V316-F324 HydrophobicContact CG2-CE2 4.34Å; V316-F324 HydrophobicContact CG2-CG 3.76Å; V316-F324 HydrophobicContact CG2-CZ 4.28Å; I320-F324 WeakPolarHBondContact O-CB 3.44Å; I320-F324 PolarHBondContact O-N 3.35Å; Y321-F324 WeakPolarHBondContact O-CB 3.45Å; Y321-F324 PolarHBondContact O-N 3.15Å; Y321-F324 VanDerWaalsContact O-N 3.17Å; D322-F324 VanDerWaalsContact C-N 3.33Å; D322-F324 PolarHBondContact O-N 3.17Å; F324-S328 VanDerWaalsContact CE1-OG 3.26Å; F324-S328 WeakPolarHBondContact CE1-OG 3.39Å; F324-S328 WeakPolarHBondContact O-CB 3.48Å; F324-S328 PolarHBondContact O-N 3.03Å; F324-S328 PolarHBondContact O-OG 2.79Å; F324-I413 HydrophobicContact CD1-CD1 4.18Å; F324-I413 HydrophobicContact CD1-CG2 4.31Å; F324-I413 HydrophobicContact CE1-CD1 4.15Å
325V98.3Very high97.9Very high11 Ų1150.1 Ų50.17%0.06726%0.259CS..Hα-helixtrans-62.5-52.5179.5168.10000110.9Y321 D322 R327 S328 V329 L374 A393 I413Y321-V325 HydrophobicContact CD1-CG2 4.05Å; Y321-V325 HydrophobicContact CE1-CG2 3.75Å; Y321-V325 HydrophobicContact CE2-CG2 4.25Å; Y321-V325 HydrophobicContact CG-CG2 4.47Å; Y321-V325 WeakPolarHBondContact O-CG2 3.24Å; Y321-V325 PolarHBondContact O-N 3.04Å; D322-V325 PolarHBondContact O-N 3.5Å; V325-R327 PolarHBondContact O-N 3.49Å; V325-S328 WeakPolarHBondContact O-CB 3.5Å; V325-S328 PolarHBondContact O-N 3.47Å; V325-V329 WeakPolarHBondContact O-CG2 3.36Å; V325-V329 PolarHBondContact O-N 2.95Å; V325-L374 HydrophobicContact CG1-CD1 3.23Å; V325-A393 HydrophobicContact CG1-CB 4.21Å; V325-A393 HydrophobicContact CG2-CB 4.34Å; V325-I413 HydrophobicContact CG2-CD1 4.07Å; V325-I413 HydrophobicContact CG2-CG2 3.99Å
326D98Very high97.8Very high108 Ų10853.9 Ų53.958%0.57828%0.279SS*.Hα-helixtrans-58.7-49.6-177.6-74.6-18.6000111.2D322 S328 V329 E330D322-D326 PolarHBondContact O-N 2.9Å; D326-S328 VanDerWaalsContact C-N 3.31Å; D326-S328 PolarHBondContact O-N 3.39Å; D326-V329 PolarHBondContact O-N 2.83Å; D326-E330 PolarHBondContact O-N 3.35Å; D326-E330 VanDerWaalsContact O-N 3.1Å
327R97.7Very high97.8Very high91 Ų9155.2 Ų55.234%0.34329%0.285SS..Hα-helixtrans-66.3-34.4179.5-174.458.7177.6157.52.4112.4I293 K323 V325 V329 E330 L331I293-R327 HydrophobicContact CD1-CB 3.86Å; I293-R327 HydrophobicContact CD1-CG 3.81Å; I293-R327 HydrophobicContact CG2-CG 4.11Å; K323-R327 WeakPolarHBondContact O-CB 3.49Å; K323-R327 PolarHBondContact O-N 2.78Å; V325-R327 PolarHBondContact O-N 3.49Å; R327-V329 VanDerWaalsContact C-N 3.34Å; R327-E330 VanDerWaalsContact CD-OE2 3.3Å; R327-E330 WeakPolarHBondContact CD-OE2 3.15Å; R327-E330 IonicContact CZ-OE2 3.88Å; R327-E330 IonicContact NE-OE2 2.93Å; R327-E330 IonicContact NH1-OE2 2.99Å; R327-E330 PolarHBondContact NH1-OE2 3.3Å; R327-E330 PolarHBondContact O-N 2.94Å; R327-L331 WeakPolarHBondContact O-CG 3.46Å; R327-L331 PolarHBondContact O-N 3.2Å
328S98.2Very high97.7Very high0 Ų053.6 Ų53.60%028%0.281CS..Hα-helixtrans-64.3-39.5174.6-71.50000112.2H297 F324 V325 D326 L331 A332H297-S328 PolarHBondContact CE1-O 2.8Å; H297-S328 VanDerWaalsContact NE2-CA 3.27Å; H297-S328 WeakPolarHBondContact NE2-CA 3.48Å; H297-S328 WeakPolarHBondContact NE2-CB 3.44Å; H297-S328 PolarHBondContact NE2-O 2.79Å; H297-S328 PolarHBondContact NE2-OG 3.33Å; F324-S328 VanDerWaalsContact CE1-OG 3.26Å; F324-S328 WeakPolarHBondContact CE1-OG 3.39Å; F324-S328 WeakPolarHBondContact O-CB 3.48Å; F324-S328 PolarHBondContact O-N 3.03Å; F324-S328 PolarHBondContact O-OG 2.79Å; V325-S328 WeakPolarHBondContact O-CB 3.5Å; V325-S328 PolarHBondContact O-N 3.47Å; D326-S328 VanDerWaalsContact C-N 3.31Å; D326-S328 PolarHBondContact O-N 3.39Å; S328-L331 PolarHBondContact O-N 3.47Å; S328-A332 VanDerWaalsContact O-CB 3.31Å; S328-A332 WeakPolarHBondContact O-CB 2.75Å; S328-A332 PolarHBondContact O-N 3.05Å
329V98.5Very high97.8Very high16 Ų1656 Ų5610%0.09729%0.289CS..Hα-helixtrans-64.9-41.5175.9171.70000111.3V325 D326 R327 K333 L374 C375 V391V325-V329 WeakPolarHBondContact O-CG2 3.36Å; V325-V329 PolarHBondContact O-N 2.95Å; D326-V329 PolarHBondContact O-N 2.83Å; R327-V329 VanDerWaalsContact C-N 3.34Å; V329-K333 HydrophobicContact CG1-CD 3.97Å; V329-K333 WeakPolarHBondContact O-CB 3.26Å; V329-K333 VanDerWaalsContact O-CG 3.31Å; V329-K333 WeakPolarHBondContact O-CG 3.38Å; V329-K333 PolarHBondContact O-N 3.23Å; V329-L374 HydrophobicContact CG2-CB 3.54Å; V329-L374 HydrophobicContact CG2-CD1 3.65Å; V329-L374 HydrophobicContact CG2-CG 4.26Å; V329-C375 HydrophobicContact CG1-CB 4.11Å; V329-V391 HydrophobicContact CG2-CB 4.49Å; V329-V391 HydrophobicContact CG2-CG1 4.32Å
330E98.2Very high97.8Very high108 Ų10851.7 Ų51.751%0.50526%0.259SS..Hα-helixtrans-59.1-51.5175.6-69.5178.2170.600111.9D326 R327 A332 K333 S334D326-E330 PolarHBondContact O-N 3.35Å; D326-E330 VanDerWaalsContact O-N 3.1Å; R327-E330 VanDerWaalsContact CD-OE2 3.3Å; R327-E330 WeakPolarHBondContact CD-OE2 3.15Å; R327-E330 IonicContact CZ-OE2 3.88Å; R327-E330 IonicContact NE-OE2 2.93Å; R327-E330 IonicContact NH1-OE2 2.99Å; R327-E330 PolarHBondContact NH1-OE2 3.3Å; R327-E330 PolarHBondContact O-N 2.94Å; E330-A332 PolarHBondContact O-N 3.24Å; E330-K333 PolarHBondContact O-N 3.3Å; E330-S334 WeakPolarHBondContact O-CB 3.36Å; E330-S334 PolarHBondContact O-N 3.41Å; E330-S334 PolarHBondContact O-OG 3.14Å
331L97.8Very high97.9Very high26 Ų2654.7 Ų54.714%0.13627%0.271CS..Hα-helixtrans-62.2-44-179.6-71.2178.7000111.8I293 R327 S328 K333 S334 R335I293-L331 HydrophobicContact CG2-CD1 3.55Å; R327-L331 WeakPolarHBondContact O-CG 3.46Å; R327-L331 PolarHBondContact O-N 3.2Å; S328-L331 PolarHBondContact O-N 3.47Å; L331-K333 VanDerWaalsContact C-N 3.33Å; L331-K333 PolarHBondContact O-N 3.4Å; L331-S334 WeakPolarHBondContact CA-OG 3.33Å; L331-S334 PolarHBondContact O-N 3.36Å; L331-S334 PolarHBondContact O-OG 2.92Å; L331-R335 PolarHBondContact O-N 2.81Å
332A98.3Very high97.8Very high3 Ų357.8 Ų57.83%0.02529%0.288CS..Hα-helixtrans-60.4-41.4177.400000112.1F301 S328 E330 S334 P389 V391F301-A332 HydrophobicContact CE2-CB 4.5Å; F301-A332 HydrophobicContact CZ-CB 4.35Å; S328-A332 VanDerWaalsContact O-CB 3.31Å; S328-A332 WeakPolarHBondContact O-CB 2.75Å; S328-A332 PolarHBondContact O-N 3.05Å; E330-A332 PolarHBondContact O-N 3.24Å; A332-S334 VanDerWaalsContact C-N 3.35Å; A332-P389 HydrophobicContact CB-CB 4.02Å; A332-P389 WeakPolarHBondContact O-CB 3.49Å; A332-P389 WeakPolarHBondContact O-CG 3.34Å; A332-V391 HydrophobicContact CB-CG2 3.73Å
333K98.2Very high97.7Very high147 Ų14758.5 Ų58.564%0.63930%0.298SS*.Hα-helixtrans-69.4-30.3176.6-74.3174.4179.8172.10113.2V329 E330 L331 R335 C375V329-K333 HydrophobicContact CG1-CD 3.97Å; V329-K333 WeakPolarHBondContact O-CB 3.26Å; V329-K333 VanDerWaalsContact O-CG 3.31Å; V329-K333 WeakPolarHBondContact O-CG 3.38Å; V329-K333 PolarHBondContact O-N 3.23Å; E330-K333 PolarHBondContact O-N 3.3Å; L331-K333 VanDerWaalsContact C-N 3.33Å; L331-K333 PolarHBondContact O-N 3.4Å; K333-R335 VanDerWaalsContact C-N 3.34Å; K333-C375 HydrophobicContact CD-CB 4.39Å; K333-C375 HydrophobicContact CG-CB 3.96Å
334S97.6Very high97.7Very high76 Ų7657 Ų5753%0.53130%0.299SS..Hα-helixtrans-81.2-10.4-178.872.20000114.4E330 L331 A332 I336E330-S334 WeakPolarHBondContact O-CB 3.36Å; E330-S334 PolarHBondContact O-N 3.41Å; E330-S334 PolarHBondContact O-OG 3.14Å; L331-S334 WeakPolarHBondContact CA-OG 3.33Å; L331-S334 PolarHBondContact O-N 3.36Å; L331-S334 PolarHBondContact O-OG 2.92Å; A332-S334 VanDerWaalsContact C-N 3.35Å; S334-I336 PolarHBondContact O-N 2.84Å
335R97.5Very high97.7Very high46 Ų4657.3 Ų57.317%0.17430%0.3CS..  trans-67.1127.8-175.4-166.3176.2-168.6925.7111.6F301 L331 K333 M337 Q346 Q347 P389F301-R335 PolarHBondContact O-NH2 2.81Å; L331-R335 PolarHBondContact O-N 2.81Å; K333-R335 VanDerWaalsContact C-N 3.34Å; R335-M337 PolarHBondContact O-N 3.02Å; R335-Q346 HydrophobicContact CG-CB 3.84Å; R335-Q346 PolarHBondContact NE-O 3.09Å; R335-Q346 PolarHBondContact NH2-O 3.14Å; R335-Q347 HydrophobicContact CG-CB 4.33Å; R335-P389 HydrophobicContact CB-CG 4.01Å; R335-P389 HydrophobicContact CG-CG 4.47Å
336I97.5Very high97.7Very high81 Ų8160.9 Ų60.942%0.41532%0.316SS..  trans-82.2115.8-178-56174.9000109.7S334 Q346 Q347S334-I336 PolarHBondContact O-N 2.84Å; I336-Q346 VanDerWaalsContact N-OE1 3.11Å; I336-Q346 PolarHBondContact O-N 2.59Å; I336-Q347 PolarHBondContact O-N 3.34Å; I336-Q347 VanDerWaalsContact O-N 3.12Å
337M97.8Very high97.7Very high27 Ų2755.8 Ų55.813%0.13329%0.289CS..BIsolated β-bridgetrans-99.8146.4170.8-64.1174.9-65.500110.1R335 Q347 W380 F386 K388R335-M337 PolarHBondContact O-N 3.02Å; M337-Q347 VanDerWaalsContact CA-O 3.26Å; M337-Q347 WeakPolarHBondContact CA-O 3.36Å; M337-Q347 HydrophobicContact CG-CB 3.98Å; M337-Q347 HydrophobicContact CG-CG 4.38Å; M337-W380 HydrophobicContact CB-CD2 4.4Å; M337-W380 HydrophobicContact CB-CE3 4.31Å; M337-W380 HydrophobicContact CB-CZ3 4.42Å; M337-W380 HydrophobicContact CE-CB 3.77Å; M337-W380 HydrophobicContact CE-CD2 3.77Å; M337-W380 HydrophobicContact CE-CG 3.34Å; M337-W380 HydrophobicContact SD-CB 4.15Å; M337-W380 HydrophobicContact SD-CD2 4.49Å; M337-W380 HydrophobicContact SD-CG 4.2Å; M337-F386 HydrophobicContact CB-CD1 4.47Å; M337-K388 HydrophobicContact CE-CG 4.11Å
338G97.2Very high97.7Very high12 Ų1251.4 Ų51.412%0.12427%0.273CS..SBendtrans170.7-157.5178.900000113.8P340 Q347 F386G338-P340 WeakPolarHBondContact O-CD 3.29Å; G338-Q347 PolarHBondContact N-O 3.02Å; G338-F386 WeakPolarHBondContact O-CE1 3.25Å; G338-F386 WeakPolarHBondContact O-CZ 3.45Å
339D97.3Very high97.7Very high88 Ų8851.4 Ų51.447%0.47127%0.273SS..  trans-57.9122173.6-175.7-12.6000109.6F341 D342 T345D339-F341 PolarHBondContact O-N 2.79Å; D339-F341 VanDerWaalsContact O-N 3.1Å; D339-F341 PolarHBondContact OD1-N 2.9Å; D339-D342 HydrophobicContact CB-CB 4.37Å; D339-D342 WeakPolarHBondContact O-CB 3.43Å; D339-D342 PolarHBondContact O-N 2.89Å; D339-T345 WeakPolarHBondContact O-CB 3.29Å; D339-T345 PolarHBondContact O-OG1 2.83Å
340P98.1Very high97.7Very high2 Ų250.7 Ų50.71%0.01327%0.268CS..THydrogen-bonded Turntrans-57.2-20.7176.8-28.538.6000115T22 T86 G90 K91 P92 Y93 G338T22-P340 HydrophobicContact CG2-CG 4.43Å; T22-P340 WeakPolarHBondContact OG1-CD 3.48Å; T22-P340 WeakPolarHBondContact OG1-CG 3.39Å; T86-P340 HydrophobicContact CG2-CB 3.49Å; T86-P340 VanDerWaalsContact CG2-CB 3.49Å; G90-P340 WeakPolarHBondContact O-CG 3.4Å; K91-P340 WeakPolarHBondContact O-CB 3.35Å; P92-P340 CarbonylContact C-O 3.56Å; P92-P340 WeakPolarHBondContact CA-O 3.38Å; Y93-P340 PolarHBondContact N-O 3.18Å; G338-P340 WeakPolarHBondContact O-CD 3.29Å
341F98.2Very high97.8Very high86 Ų8645.8 Ų45.838%0.37725%0.245SC..THydrogen-bonded Turntrans-85.9-12.4175.8-71.4-79.1000114.1S83 T86 L87 Y93 D339S83-F341 WeakPolarHBondContact O-CZ 3.45Å; T86-F341 HydrophobicContact CG2-CD1 4.18Å; T86-F341 HydrophobicContact CG2-CD2 4.02Å; T86-F341 HydrophobicContact CG2-CE1 3.89Å; T86-F341 HydrophobicContact CG2-CE2 3.71Å; T86-F341 HydrophobicContact CG2-CG 4.25Å; T86-F341 HydrophobicContact CG2-CZ 3.65Å; L87-F341 HydrophobicContact CB-CE2 4.44Å; L87-F341 HydrophobicContact CB-CZ 4.26Å; Y93-F341 HydrophobicContact CD2-CD1 4.13Å; Y93-F341 HydrophobicContact CD2-CE1 4Å; Y93-F341 HydrophobicContact CG-CD1 4.35Å; D339-F341 PolarHBondContact O-N 2.79Å; D339-F341 VanDerWaalsContact O-N 3.1Å; D339-F341 PolarHBondContact OD1-N 2.9Å
342D97.6Very high97.8Very high69 Ų6946.2 Ų46.237%0.36925%0.248SC..SBendtrans-71.8123172.1-174.3-38.9000109.2D339 T344 T345D339-D342 HydrophobicContact CB-CB 4.37Å; D339-D342 WeakPolarHBondContact O-CB 3.43Å; D339-D342 PolarHBondContact O-N 2.89Å; D342-T344 PolarHBondContact O-N 3.09Å; D342-T344 WeakPolarHBondContact OD1-CB 3.2Å; D342-T344 PolarHBondContact OD1-N 3.4Å; D342-T344 PolarHBondContact OD1-OG1 2.96Å; D342-T345 WeakPolarHBondContact O-CB 3.5Å; D342-T345 PolarHBondContact O-N 2.83Å
343P95.5Very high97.7Very high122 Ų12251.9 Ų51.979%0.79227%0.272SS*.THydrogen-bonded Turntrans-63.4-14-177.726.9-35.8000114
344T97Very high97.7Very high79 Ų7949.8 Ų49.849%0.48527%0.271SS..THydrogen-bonded Turntrans-89.8-15.9176.270.80000113.2D342 Q346D342-T344 PolarHBondContact O-N 3.09Å; D342-T344 WeakPolarHBondContact OD1-CB 3.2Å; D342-T344 PolarHBondContact OD1-N 3.4Å; D342-T344 PolarHBondContact OD1-OG1 2.96Å; T344-Q346 PolarHBondContact O-N 2.66Å
345T97.8Very high97.7Very high6 Ų646.7 Ų46.74%0.03725%0.249CC..  trans-66.8124.1179.2-69.90000110.7P92 D339 D342 Q347P92-T345 HydrophobicContact CG-CG2 4.36Å; D339-T345 WeakPolarHBondContact O-CB 3.29Å; D339-T345 PolarHBondContact O-OG1 2.83Å; D342-T345 WeakPolarHBondContact O-CB 3.5Å; D342-T345 PolarHBondContact O-N 2.83Å; T345-Q347 WeakPolarHBondContact CG2-O 3.4Å
346Q97.3Very high97.8Very high86 Ų8646 Ų4640%0.40225%0.247SC..SBendtrans-100.4-16.4176.8-63.3176.5-39.700112.5R335 I336 T344R335-Q346 HydrophobicContact CG-CB 3.84Å; R335-Q346 PolarHBondContact NE-O 3.09Å; R335-Q346 PolarHBondContact NH2-O 3.14Å; I336-Q346 VanDerWaalsContact N-OE1 3.11Å; I336-Q346 PolarHBondContact O-N 2.59Å; T344-Q346 PolarHBondContact O-N 2.66Å
347Q98.4Very high97.8Very high0 Ų046.9 Ų46.90%025%0.249CC..BIsolated β-bridgetrans-148.2120-177.3-168176.2-73.900111.6Q304 R335 I336 M337 G338 T345 I387Q304-Q347 HydrophobicContact CB-CG 4.46Å; Q304-Q347 HydrophobicContact CG-CG 3.65Å; R335-Q347 HydrophobicContact CG-CB 4.33Å; I336-Q347 PolarHBondContact O-N 3.34Å; I336-Q347 VanDerWaalsContact O-N 3.12Å; M337-Q347 VanDerWaalsContact CA-O 3.26Å; M337-Q347 WeakPolarHBondContact CA-O 3.36Å; M337-Q347 HydrophobicContact CG-CB 3.98Å; M337-Q347 HydrophobicContact CG-CG 4.38Å; G338-Q347 PolarHBondContact N-O 3.02Å; T345-Q347 WeakPolarHBondContact CG2-O 3.4Å; Q347-I387 PolarHBondContact NE2-O 3.17Å
348G98.3Very high97.8Very high0 Ų050.5 Ų50.50%026%0.261CS..  trans-88.4-161.5172.200000113.6G90 Q304 F386G90-G348 WeakPolarHBondContact O-CA 3.41Å; Q304-G348 VanDerWaalsContact CD-N 3.34Å; Q304-G348 WeakPolarHBondContact CG-O 3.43Å; Q304-G348 PolarHBondContact NE2-O 3.4Å; G348-F386 WeakPolarHBondContact O-CD1 3.4Å
349P98.6Very high97.9Very high0 Ų049.9 Ų49.90%026%0.255CS..  trans-77.8169.3175.635.5-41.9000113.2P21 G90 Q304 F386P21-P349 VanDerWaalsContact C-CG 3.49Å; P21-P349 HydrophobicContact CB-CB 4.2Å; P21-P349 HydrophobicContact CB-CG 3.69Å; P21-P349 HydrophobicContact CG-CG 3.93Å; P21-P349 VanDerWaalsContact O-CB 3.3Å; P21-P349 WeakPolarHBondContact O-CB 3.16Å; P21-P349 WeakPolarHBondContact O-CG 3.4Å; G90-P349 WeakPolarHBondContact O-CD 3.25Å; Q304-P349 WeakPolarHBondContact CG-O 3.36Å; Q304-P349 PolarHBondContact NE2-O 3.19Å; P349-F386 HydrophobicContact CB-CD1 4.24Å; P349-F386 HydrophobicContact CB-CD2 4.06Å; P349-F386 HydrophobicContact CB-CE1 4.24Å; P349-F386 HydrophobicContact CB-CE2 4.04Å; P349-F386 HydrophobicContact CB-CG 4.16Å; P349-F386 HydrophobicContact CB-CZ 4.14Å; P349-F386 HydrophobicContact CG-CZ 4.33Å
350Q98.7Very high98Very high0 Ų047.5 Ų47.50%024%0.242CC..  trans-72.4162.5161.1-52.8-50.6-60.900110.4P21 D352 K356 I359 Y385 I387P21-Q350 VanDerWaalsContact CB-O 3.22Å; P21-Q350 WeakPolarHBondContact CB-O 3.47Å; Q350-D352 PolarHBondContact O-N 3.06Å; Q350-K356 HydrophobicContact CB-CB 4.42Å; Q350-K356 HydrophobicContact CG-CB 4.47Å; Q350-I359 HydrophobicContact CG-CD1 3.78Å; Q350-I359 VanDerWaalsContact OE1-CD1 3.23Å; Q350-Y385 WeakPolarHBondContact CB-O 2.96Å; Q350-Y385 WeakPolarHBondContact CG-O 3.25Å; Q350-Y385 PolarHBondContact N-O 2.83Å; Q350-Y385 WeakPolarHBondContact O-CB 3.34Å; Q350-I387 HydrophobicContact CG-CD1 3.76Å; Q350-I387 HydrophobicContact CG-CG1 3.98Å
351I98.6Very high98Very high6 Ų651.4 Ų51.43%0.03126%0.263CS..SBendtrans-64.6-38.4-172.2-171.359.4000114.9P21 W147 Q175 T176 H355P21-I351 WeakPolarHBondContact CB-O 3.26Å; W147-I351 HydrophobicContact CB-CD1 4.48Å; W147-I351 HydrophobicContact CB-CG1 4.15Å; W147-I351 HydrophobicContact CD2-CB 3.97Å; W147-I351 HydrophobicContact CD2-CG1 3.83Å; W147-I351 HydrophobicContact CD2-CG2 3.7Å; W147-I351 HydrophobicContact CE3-CB 3.47Å; W147-I351 VanDerWaalsContact CE3-CB 3.47Å; W147-I351 HydrophobicContact CE3-CD1 4.23Å; W147-I351 HydrophobicContact CE3-CG1 3.61Å; W147-I351 HydrophobicContact CE3-CG2 3.59Å; W147-I351 HydrophobicContact CG-CG1 4.05Å; W147-I351 HydrophobicContact CG-CG2 4.48Å; W147-I351 HydrophobicContact CH2-CB 4.13Å; W147-I351 HydrophobicContact CH2-CG2 3.52Å; W147-I351 HydrophobicContact CZ2-CG2 3.65Å; W147-I351 HydrophobicContact CZ3-CB 3.57Å; W147-I351 HydrophobicContact CZ3-CG1 4.25Å; W147-I351 HydrophobicContact CZ3-CG2 3.51Å; Q175-I351 HydrophobicContact CB-CD1 4.08Å; Q175-I351 HydrophobicContact CB-CG1 3.75Å; Q175-I351 HydrophobicContact CG-CG1 4.01Å; T176-I351 HydrophobicContact CG2-CD1 3.74Å; I351-H355 HydrophobicContact CG2-CB 4Å
352D98.1Very high98Very high34 Ų3447.8 Ų47.818%0.18225%0.247CC..  trans-152.1171.3-178.168.634.3000111.8Q175 Q350 T354 H355 K356 Y385Q175-D352 PolarHBondContact NE2-OD2 3.28Å; Q350-D352 PolarHBondContact O-N 3.06Å; D352-T354 PolarHBondContact OD1-N 2.75Å; D352-T354 VanDerWaalsContact OD1-N 3.1Å; D352-H355 VanDerWaalsContact OD1-CB 3.28Å; D352-H355 WeakPolarHBondContact OD1-CB 3.28Å; D352-H355 PolarHBondContact OD1-N 3.48Å; D352-K356 PolarHBondContact O-N 3.01Å; D352-Y385 VanDerWaalsContact CA-CD2 3.45Å
353K97.4Very high98.1Very high122 Ų12244.5 Ų44.553%0.5323%0.23SC..Hα-helixtrans-61.4-44179.7-178.2177.2171.7-179.30112H355 K356 E357 Y385K353-H355 VanDerWaalsContact C-N 3.34Å; K353-H355 PolarHBondContact O-N 3.06Å; K353-K356 PolarHBondContact O-N 3.16Å; K353-E357 WeakPolarHBondContact CE-OE1 3.47Å; K353-E357 IonicContact NZ-OE1 3.61Å; K353-E357 WeakPolarHBondContact O-CG 3.47Å; K353-E357 PolarHBondContact O-N 3.44Å; K353-Y385 HydrophobicContact CB-CD1 4.18Å; K353-Y385 HydrophobicContact CB-CE1 3.75Å
354T97.7Very high98.2Very high103 Ų10342.5 Ų42.563%0.63221%0.21SC*.Hα-helixtrans-62.3-42.9-177.8-61.20000111.2D352 E357 R358D352-T354 PolarHBondContact OD1-N 2.75Å; D352-T354 VanDerWaalsContact OD1-N 3.1Å; T354-E357 PolarHBondContact O-N 3.26Å; T354-R358 WeakPolarHBondContact O-CB 3.34Å; T354-R358 PolarHBondContact O-N 2.92Å
355H98.3Very high98.3Very high12 Ų1241.9 Ų41.96%0.05620%0.2CC..Hα-helixtrans-68.2-41.2177.7-16846.2000111.6W147 Q306 I351 D352 K353 E357 R358 I359 F407W147-H355 AromaticContact CH2-CD2 3.76Å; W147-H355 AromaticContact CH2-NE2 3.85Å; Q306-H355 PolarHBondContact OE1-CD2 2.95Å; I351-H355 HydrophobicContact CG2-CB 4Å; D352-H355 VanDerWaalsContact OD1-CB 3.28Å; D352-H355 WeakPolarHBondContact OD1-CB 3.28Å; D352-H355 PolarHBondContact OD1-N 3.48Å; K353-H355 VanDerWaalsContact C-N 3.34Å; K353-H355 PolarHBondContact O-N 3.06Å; H355-E357 PolarHBondContact O-N 3.3Å; H355-R358 WeakPolarHBondContact O-CB 3.37Å; H355-R358 PolarHBondContact O-N 3.01Å; H355-I359 WeakPolarHBondContact NE2-CD1 3.49Å; H355-I359 WeakPolarHBondContact O-CG1 3.21Å; H355-I359 PolarHBondContact O-N 3.25Å; H355-F407 PolarHBondContact CE1-O 3.11Å; H355-F407 AromaticContact NE2-CD1 3.92Å; H355-F407 PolarHBondContact NE2-O 3.3Å
356K98.2Very high98.3Very high31 Ų3141.6 Ų41.614%0.13520%0.199CC..Hα-helixtrans-57.1-48.7172.4168.8174.2179179.90112.1Q350 D352 K353 R358 I359 L360 S379 G384 Y385 I387Q350-K356 HydrophobicContact CB-CB 4.42Å; Q350-K356 HydrophobicContact CG-CB 4.47Å; D352-K356 PolarHBondContact O-N 3.01Å; K353-K356 PolarHBondContact O-N 3.16Å; K356-R358 VanDerWaalsContact C-N 3.34Å; K356-R358 PolarHBondContact O-N 3.47Å; K356-I359 PolarHBondContact O-N 2.89Å; K356-L360 HydrophobicContact CG-CD1 4.1Å; K356-L360 WeakPolarHBondContact O-CG 3.42Å; K356-L360 PolarHBondContact O-N 2.96Å; K356-S379 WeakPolarHBondContact CE-OG 3.48Å; K356-S379 PolarHBondContact NZ-OG 3.3Å; K356-G384 PolarHBondContact NZ-O 3.22Å; K356-Y385 HydrophobicContact CD-CD1 4.45Å; K356-I387 HydrophobicContact CB-CD1 4.34Å; K356-I387 HydrophobicContact CG-CD1 3.99Å; K356-I387 HydrophobicContact CG-CG1 4.01Å
357E98.2Very high98.3Very high100 Ų10041 Ų4147%0.46719%0.194SC..Hα-helixtrans-63-40.9179.1-72.7171.5173.800111.7K353 T354 H355 I359 L360 N361K353-E357 WeakPolarHBondContact CE-OE1 3.47Å; K353-E357 IonicContact NZ-OE1 3.61Å; K353-E357 WeakPolarHBondContact O-CG 3.47Å; K353-E357 PolarHBondContact O-N 3.44Å; T354-E357 PolarHBondContact O-N 3.26Å; H355-E357 PolarHBondContact O-N 3.3Å; E357-I359 PolarHBondContact O-N 3.44Å; E357-L360 PolarHBondContact O-N 3.17Å; E357-N361 WeakPolarHBondContact O-CB 3.45Å; E357-N361 PolarHBondContact O-N 3.36Å
358R98.4Very high98.3Very high102 Ų10248.2 Ų48.239%0.38523%0.228SC..Hα-helixtrans-58.1-46.3174.2178.9177.1173.1-111.8-8.3111.9T354 H355 K356 N361 F362 E405T354-R358 WeakPolarHBondContact O-CB 3.34Å; T354-R358 PolarHBondContact O-N 2.92Å; H355-R358 WeakPolarHBondContact O-CB 3.37Å; H355-R358 PolarHBondContact O-N 3.01Å; K356-R358 VanDerWaalsContact C-N 3.34Å; K356-R358 PolarHBondContact O-N 3.47Å; R358-N361 WeakPolarHBondContact O-CB 3.14Å; R358-N361 PolarHBondContact O-N 2.81Å; R358-F362 HydrophobicContact CG-CD2 4.15Å; R358-F362 HydrophobicContact CG-CE2 3.88Å; R358-F362 VanDerWaalsContact O-CD2 3.29Å; R358-F362 WeakPolarHBondContact O-CD2 3.38Å; R358-F362 PolarHBondContact O-N 3.11Å; R358-F362 VanDerWaalsContact O-N 3.1Å; R358-E405 PolarHBondContact NH2-O 3.01Å
359I98.7Very high98.3Very high0 Ų052.5 Ų52.50%025%0.248CC..Hα-helixtrans-63.4-45.9178.1-67.1160.3000111Q350 H355 K356 E357 N361 F362 I363 I387 I406 V410Q350-I359 HydrophobicContact CG-CD1 3.78Å; Q350-I359 VanDerWaalsContact OE1-CD1 3.23Å; H355-I359 WeakPolarHBondContact NE2-CD1 3.49Å; H355-I359 WeakPolarHBondContact O-CG1 3.21Å; H355-I359 PolarHBondContact O-N 3.25Å; K356-I359 PolarHBondContact O-N 2.89Å; E357-I359 PolarHBondContact O-N 3.44Å; I359-N361 VanDerWaalsContact C-N 3.27Å; I359-N361 PolarHBondContact O-N 3Å; I359-F362 WeakPolarHBondContact O-CB 3.36Å; I359-F362 PolarHBondContact O-N 3.48Å; I359-F362 VanDerWaalsContact O-N 3.14Å; I359-I363 HydrophobicContact CG2-CD1 3.99Å; I359-I363 WeakPolarHBondContact O-CG1 3.16Å; I359-I363 PolarHBondContact O-N 2.83Å; I359-I387 HydrophobicContact CB-CD1 3.57Å; I359-I387 HydrophobicContact CD1-CD1 3.88Å; I359-I387 HydrophobicContact CG1-CD1 4.35Å; I359-I387 HydrophobicContact CG2-CD1 3.48Å; I359-I387 VanDerWaalsContact CG2-CD1 3.48Å; I359-I387 HydrophobicContact CG2-CG2 4.46Å; I359-I406 HydrophobicContact CB-CG2 4.34Å; I359-I406 HydrophobicContact CG1-CG2 4.08Å; I359-I406 HydrophobicContact CG2-CG2 3.98Å; I359-V410 HydrophobicContact CG2-CG2 3.85Å
360L98.6Very high98.3Very high38 Ų3855 Ų5520%0.19927%0.274CS..Hα-helixtrans-60.6-38.3178-68.2171.5000111.6K356 E357 I363 E364 I387K356-L360 HydrophobicContact CG-CD1 4.1Å; K356-L360 WeakPolarHBondContact O-CG 3.42Å; K356-L360 PolarHBondContact O-N 2.96Å; E357-L360 PolarHBondContact O-N 3.17Å; L360-I363 HydrophobicContact CD2-CD1 4.37Å; L360-I363 WeakPolarHBondContact O-CB 3.25Å; L360-I363 PolarHBondContact O-N 3.05Å; L360-E364 PolarHBondContact O-N 2.86Å; L360-I387 HydrophobicContact CD2-CD1 4.46Å; L360-I387 HydrophobicContact CG-CD1 4.27Å
361N98.6Very high98.2Very high84 Ų8455.3 Ų55.345%0.44928%0.277SS..Hα-helixtrans-63.5-40.9174.3-17548.6000112.5E357 R358 I359 I363 E364 K365E357-N361 WeakPolarHBondContact O-CB 3.45Å; E357-N361 PolarHBondContact O-N 3.36Å; R358-N361 WeakPolarHBondContact O-CB 3.14Å; R358-N361 PolarHBondContact O-N 2.81Å; I359-N361 VanDerWaalsContact C-N 3.27Å; I359-N361 PolarHBondContact O-N 3Å; N361-I363 VanDerWaalsContact C-N 3.32Å; N361-I363 PolarHBondContact O-N 3.01Å; N361-E364 PolarHBondContact O-N 2.85Å; N361-K365 WeakPolarHBondContact O-CG 3.29Å; N361-K365 PolarHBondContact O-N 2.84Å
362F98.6Very high98.2Very high9 Ų960.5 Ų60.54%0.03930%0.299CS..Hα-helixtrans-62-40173.2-84.2-67.3000112.5R358 I359 K365 G366 I400 V401 E404 I406R358-F362 HydrophobicContact CG-CD2 4.15Å; R358-F362 HydrophobicContact CG-CE2 3.88Å; R358-F362 VanDerWaalsContact O-CD2 3.29Å; R358-F362 WeakPolarHBondContact O-CD2 3.38Å; R358-F362 PolarHBondContact O-N 3.11Å; R358-F362 VanDerWaalsContact O-N 3.1Å; I359-F362 WeakPolarHBondContact O-CB 3.36Å; I359-F362 PolarHBondContact O-N 3.48Å; I359-F362 VanDerWaalsContact O-N 3.14Å; F362-K365 PolarHBondContact O-N 3.48Å; F362-G366 PolarHBondContact O-N 2.9Å; F362-I400 HydrophobicContact CD1-CD1 4.17Å; F362-I400 HydrophobicContact CD1-CG1 4.29Å; F362-I400 HydrophobicContact CD1-CG2 4.43Å; F362-I400 HydrophobicContact CE1-CD1 3.77Å; F362-I400 HydrophobicContact CE1-CG1 3.93Å; F362-V401 WeakPolarHBondContact O-CG1 3.48Å; F362-E404 HydrophobicContact CE1-CB 3.72Å; F362-E404 HydrophobicContact CE1-CG 4.45Å; F362-E404 WeakPolarHBondContact CE1-OE2 3.47Å; F362-E404 HydrophobicContact CZ-CB 4.02Å; F362-E404 VanDerWaalsContact CZ-OE2 3.29Å; F362-E404 WeakPolarHBondContact CZ-OE2 3.42Å; F362-I406 HydrophobicContact CB-CD1 4.24Å; F362-I406 HydrophobicContact CB-CG1 3.99Å; F362-I406 HydrophobicContact CB-CG2 4.12Å; F362-I406 HydrophobicContact CD1-CG1 4.22Å; F362-I406 HydrophobicContact CD2-CB 4.38Å; F362-I406 HydrophobicContact CD2-CG1 4.23Å; F362-I406 HydrophobicContact CD2-CG2 4.19Å; F362-I406 HydrophobicContact CG-CG1 3.91Å; F362-I406 HydrophobicContact CG-CG2 4.38Å
363I98.7Very high98.2Very high0 Ų061.7 Ų61.70%031%0.305CS..Hα-helixtrans-61-45.7176.1-69.3164.4000110.3I359 L360 N361 G366 K367 I387 T390 F392 V410I359-I363 HydrophobicContact CG2-CD1 3.99Å; I359-I363 WeakPolarHBondContact O-CG1 3.16Å; I359-I363 PolarHBondContact O-N 2.83Å; L360-I363 HydrophobicContact CD2-CD1 4.37Å; L360-I363 WeakPolarHBondContact O-CB 3.25Å; L360-I363 PolarHBondContact O-N 3.05Å; N361-I363 VanDerWaalsContact C-N 3.32Å; N361-I363 PolarHBondContact O-N 3.01Å; I363-G366 PolarHBondContact O-N 3.2Å; I363-K367 WeakPolarHBondContact O-CG 3.32Å; I363-K367 PolarHBondContact O-N 2.96Å; I363-K367 VanDerWaalsContact O-N 3.13Å; I363-I387 HydrophobicContact CD1-CG2 4.33Å; I363-T390 HydrophobicContact CD1-CG2 4.36Å; I363-T390 HydrophobicContact CG1-CG2 4.34Å; I363-F392 HydrophobicContact CG1-CE2 4.46Å; I363-F392 HydrophobicContact CG2-CE2 4.41Å; I363-F392 HydrophobicContact CG2-CZ 4.14Å; I363-F392 WeakPolarHBondContact O-CZ 3.31Å; I363-V410 HydrophobicContact CD1-CG2 3.92Å; I363-V410 HydrophobicContact CG1-CG1 4.24Å; I363-V410 HydrophobicContact CG1-CG2 3.95Å
364E98.6Very high98.3Very high80 Ų8058 Ų5837%0.37429%0.291SS..Hα-helixtrans-63.1-43.7177.3-68.5-49.6128.100112.4L360 N361 G366 K367 Q368L360-E364 PolarHBondContact O-N 2.86Å; N361-E364 PolarHBondContact O-N 2.85Å; E364-G366 VanDerWaalsContact C-N 3.33Å; E364-G366 PolarHBondContact O-N 2.83Å; E364-K367 WeakPolarHBondContact O-CB 2.96Å; E364-K367 PolarHBondContact O-N 3.3Å; E364-K367 IonicContact OE1-NZ 3.57Å; E364-K367 PolarHBondContact OE1-NZ 2.99Å; E364-K367 IonicContact OE2-NZ 3.94Å; E364-Q368 WeakPolarHBondContact O-CG 3.13Å; E364-Q368 PolarHBondContact O-N 3.07Å
365K98.3Very high98.3Very high67 Ų6753.7 Ų53.729%0.29127%0.265SS..Hα-helixtrans-61.3-41175-68178.5178.9-1770112.2N361 F362 K367 Q368 E369 I400N361-K365 WeakPolarHBondContact O-CG 3.29Å; N361-K365 PolarHBondContact O-N 2.84Å; F362-K365 PolarHBondContact O-N 3.48Å; K365-K367 VanDerWaalsContact C-N 3.31Å; K365-K367 PolarHBondContact O-N 3.31Å; K365-Q368 WeakPolarHBondContact O-CB 3.16Å; K365-Q368 PolarHBondContact O-N 3.49Å; K365-Q368 VanDerWaalsContact O-N 3.11Å; K365-E369 WeakPolarHBondContact O-CG 3.22Å; K365-E369 PolarHBondContact O-N 3.39Å; K365-I400 HydrophobicContact CB-CG2 3.66Å; K365-I400 HydrophobicContact CD-CD1 3.61Å; K365-I400 HydrophobicContact CD-CG2 4.19Å
366G98.3Very high98.3Very high0 Ų054.4 Ų54.40%028%0.275CS..Hα-helixtrans-57.1-43.217500000112.6F362 I363 E364 E369 G370 A371F362-G366 PolarHBondContact O-N 2.9Å; I363-G366 PolarHBondContact O-N 3.2Å; E364-G366 VanDerWaalsContact C-N 3.33Å; E364-G366 PolarHBondContact O-N 2.83Å; G366-E369 PolarHBondContact O-N 2.94Å; G366-G370 PolarHBondContact O-N 2.79Å; G366-A371 VanDerWaalsContact O-CB 3.25Å; G366-A371 WeakPolarHBondContact O-CB 3.35Å; G366-A371 PolarHBondContact O-N 3.46Å
367K98Very high98.3Very high72 Ų7253 Ų5331%0.31327%0.27SS..Hα-helixtrans-62.5-44.2173.6-64.2168-176.2168.60111.9I363 E364 K365 E369 G370 L373 F392I363-K367 WeakPolarHBondContact O-CG 3.32Å; I363-K367 PolarHBondContact O-N 2.96Å; I363-K367 VanDerWaalsContact O-N 3.13Å; E364-K367 WeakPolarHBondContact O-CB 2.96Å; E364-K367 PolarHBondContact O-N 3.3Å; E364-K367 IonicContact OE1-NZ 3.57Å; E364-K367 PolarHBondContact OE1-NZ 2.99Å; E364-K367 IonicContact OE2-NZ 3.94Å; K365-K367 VanDerWaalsContact C-N 3.31Å; K365-K367 PolarHBondContact O-N 3.31Å; K367-E369 VanDerWaalsContact C-N 3.31Å; K367-E369 PolarHBondContact O-N 3.35Å; K367-G370 PolarHBondContact O-N 3.34Å; K367-L373 HydrophobicContact CD-CD2 4.47Å; K367-L373 HydrophobicContact CG-CB 4.46Å; K367-F392 HydrophobicContact CG-CE1 4.15Å; K367-F392 HydrophobicContact CG-CZ 4.25Å
368Q98.1Very high98.3Very high153 Ų15351.2 Ų51.272%0.71527%0.266SS*.Hα-helixtrans-64.7-35-178.4-71169.55.400112.6E364 K365 G370E364-Q368 WeakPolarHBondContact O-CG 3.13Å; E364-Q368 PolarHBondContact O-N 3.07Å; K365-Q368 WeakPolarHBondContact O-CB 3.16Å; K365-Q368 PolarHBondContact O-N 3.49Å; K365-Q368 VanDerWaalsContact O-N 3.11Å; Q368-G370 VanDerWaalsContact C-N 3.26Å; Q368-G370 PolarHBondContact O-N 3.48Å
369E98.1Very high98.2Very high89 Ų8948.5 Ų48.542%0.41626%0.262SS..THydrogen-bonded Turntrans-82.9-1.4178.4-67.6176176.400113.5K365 G366 K367 M399 I400K365-E369 WeakPolarHBondContact O-CG 3.22Å; K365-E369 PolarHBondContact O-N 3.39Å; G366-E369 PolarHBondContact O-N 2.94Å; K367-E369 VanDerWaalsContact C-N 3.31Å; K367-E369 PolarHBondContact O-N 3.35Å; E369-M399 HydrophobicContact CB-CG 4.14Å; E369-M399 WeakPolarHBondContact O-CE 3.39Å; E369-M399 WeakPolarHBondContact OE2-CA 3.13Å; E369-M399 WeakPolarHBondContact OE2-CB 3.49Å; E369-I400 WeakPolarHBondContact OE2-CG2 3.26Å; E369-I400 PolarHBondContact OE2-N 2.94Å
370G97.5Very high98.2Very high53 Ų5353.3 Ų53.355%0.54628%0.281SS..THydrogen-bonded Turntrans97.57.5172.600000115.5G366 K367 Q368 K372G366-G370 PolarHBondContact O-N 2.79Å; K367-G370 PolarHBondContact O-N 3.34Å; Q368-G370 VanDerWaalsContact C-N 3.26Å; Q368-G370 PolarHBondContact O-N 3.48Å; G370-K372 PolarHBondContact O-N 3.27Å
371A98Very high97.9Very high6 Ų653.8 Ų53.85%0.0529%0.294CS..  trans-65133.9171.400000110.1G366 L373 F392 V395 M399 V401G366-A371 VanDerWaalsContact O-CB 3.25Å; G366-A371 WeakPolarHBondContact O-CB 3.35Å; G366-A371 PolarHBondContact O-N 3.46Å; A371-L373 PolarHBondContact O-N 3.46Å; A371-F392 HydrophobicContact CB-CB 4.33Å; A371-F392 HydrophobicContact CB-CD1 3.54Å; A371-F392 HydrophobicContact CB-CE1 4.03Å; A371-F392 HydrophobicContact CB-CG 4.09Å; A371-V395 HydrophobicContact CB-CG2 4.18Å; A371-M399 HydrophobicContact CB-CE 4.43Å; A371-M399 HydrophobicContact CB-SD 3.87Å; A371-V401 HydrophobicContact CB-CG2 4.33Å
372K98.4Very high97.6Very high116 Ų11658.2 Ų58.250%0.50432%0.318SS..EExtended strand (participates in β ladder)trans-81.7104.1-175.2-172.2-177.9178.7-175.20110.7G370 L374 F392 A393 D394G370-K372 PolarHBondContact O-N 3.27Å; K372-L374 HydrophobicContact CD-CD2 3.84Å; K372-L374 HydrophobicContact CG-CD2 3.84Å; K372-L374 PolarHBondContact O-N 2.81Å; K372-F392 WeakPolarHBondContact O-CA 3.31Å; K372-A393 WeakPolarHBondContact CB-O 3.45Å; K372-A393 PolarHBondContact N-O 3.05Å; K372-A393 PolarHBondContact O-N 3.41Å; K372-D394 WeakPolarHBondContact CD-OD2 3.27Å
373L98.6Very high97.4Very high58 Ų5864.8 Ų64.830%0.30435%0.347SS..EExtended strand (participates in β ladder)trans-71119.8174-179.366.5000110.5K367 A371 C375 T390 F392K367-L373 HydrophobicContact CD-CD2 4.47Å; K367-L373 HydrophobicContact CG-CB 4.46Å; A371-L373 PolarHBondContact O-N 3.46Å; L373-C375 VanDerWaalsContact CD1-O 3.3Å; L373-C375 WeakPolarHBondContact CD1-O 3.35Å; L373-T390 HydrophobicContact CD1-CG2 3.53Å; L373-F392 HydrophobicContact CB-CD1 4.07Å; L373-F392 HydrophobicContact CB-CE1 3.66Å; L373-F392 HydrophobicContact CB-CZ 4.4Å; L373-F392 HydrophobicContact CD1-CD1 4.34Å; L373-F392 HydrophobicContact CD1-CE1 4Å; L373-F392 HydrophobicContact CD1-CE2 4.43Å; L373-F392 HydrophobicContact CD1-CZ 4.04Å; L373-F392 HydrophobicContact CG-CE1 4.41Å
374L98.5Very high97.3Very high46 Ų4665.4 Ų65.424%0.24135%0.353CS..EExtended strand (participates in β ladder)trans-102.9-33.1-178.6-60.3-179.2000113.9V325 V329 K372 V391 A393V325-L374 HydrophobicContact CG1-CD1 3.23Å; V329-L374 HydrophobicContact CG2-CB 3.54Å; V329-L374 HydrophobicContact CG2-CD1 3.65Å; V329-L374 HydrophobicContact CG2-CG 4.26Å; K372-L374 HydrophobicContact CD-CD2 3.84Å; K372-L374 HydrophobicContact CG-CD2 3.84Å; K372-L374 PolarHBondContact O-N 2.81Å; L374-V391 HydrophobicContact CD1-CG1 4.44Å; L374-V391 PolarHBondContact N-O 3.23Å; L374-A393 HydrophobicContact CD1-CB 3.51Å; L374-A393 HydrophobicContact CG-CB 4.1Å
375C98.4Very high97.3Very high12 Ų1263.4 Ų63.48%0.08134%0.342CS..EExtended strand (participates in β ladder)trans-157.8165.2174.269.80000112V329 K333 L373 T390 V391V329-C375 HydrophobicContact CG1-CB 4.11Å; K333-C375 HydrophobicContact CD-CB 4.39Å; K333-C375 HydrophobicContact CG-CB 3.96Å; L373-C375 VanDerWaalsContact CD1-O 3.3Å; L373-C375 WeakPolarHBondContact CD1-O 3.35Å; C375-T390 WeakPolarHBondContact O-CA 3.45Å; C375-V391 PolarHBondContact O-N 3.01Å
376G98.2Very high97.3Very high26 Ų2660.6 Ų60.627%0.26833%0.33SS..  trans78.2-126.7177.700000112.7T378 P389G376-T378 VanDerWaalsContact C-N 3.27Å; G376-T378 PolarHBondContact O-N 2.71Å; G376-T378 PolarHBondContact O-OG1 2.84Å; G376-P389 WeakPolarHBondContact CA-O 3.34Å
377G97.5Very high97.3Very high2 Ų260.6 Ų60.62%0.02133%0.33CS..  trans73.911.7172.900000115.5T390G377-T390 PolarHBondContact N-OG1 3.14Å
378T97.9Very high97.3Very high63 Ų6360.9 Ų60.939%0.38733%0.331SS..SBendtrans-146.9163.7-173.348.50000111.5G376 K388G376-T378 VanDerWaalsContact C-N 3.27Å; G376-T378 PolarHBondContact O-N 2.71Å; G376-T378 PolarHBondContact O-OG1 2.84Å; T378-K388 PolarHBondContact O-N 3.4Å; T378-K388 WeakPolarHBondContact OG1-CD 3.42Å; T378-K388 PolarHBondContact OG1-NZ 3.06Å
379S97.5Very high97.3Very high45 Ų4554 Ų5432%0.31530%0.299SS..BIsolated β-bridgetrans-65.3164.5168.9-62.70000111.8K356 F386 K388K356-S379 WeakPolarHBondContact CE-OG 3.48Å; K356-S379 PolarHBondContact NZ-OG 3.3Å; S379-F386 WeakPolarHBondContact CA-O 3.49Å; S379-K388 WeakPolarHBondContact O-CE 3.07Å
380W97.6Very high97.4Very high101 Ų10149.7 Ų49.738%0.38328%0.28SS..  trans-132.4141.3172.2-178.489.5000110.9M337 F386 K388M337-W380 HydrophobicContact CB-CD2 4.4Å; M337-W380 HydrophobicContact CB-CE3 4.31Å; M337-W380 HydrophobicContact CB-CZ3 4.42Å; M337-W380 HydrophobicContact CE-CB 3.77Å; M337-W380 HydrophobicContact CE-CD2 3.77Å; M337-W380 HydrophobicContact CE-CG 3.34Å; M337-W380 HydrophobicContact SD-CB 4.15Å; M337-W380 HydrophobicContact SD-CD2 4.49Å; M337-W380 HydrophobicContact SD-CG 4.2Å; W380-F386 HydrophobicContact CB-CB 4.15Å; W380-F386 HydrophobicContact CE3-CB 4.09Å; W380-F386 HydrophobicContact CE3-CD1 4.13Å; W380-F386 HydrophobicContact CE3-CD2 4.32Å; W380-F386 AromaticContact CE3-CG 3.94Å; W380-F386 HydrophobicContact CE3-CG 3.94Å; W380-F386 HydrophobicContact CZ3-CD1 4.42Å; W380-F386 HydrophobicContact CZ3-CE1 4.49Å; W380-F386 HydrophobicContact CZ3-CG 4.45Å; W380-F386 PolarHBondContact N-O 3.25Å; W380-F386 WeakPolarHBondContact O-CB 3.3Å; W380-K388 HydrophobicContact CB-CG 3.97Å
381G93.6Very high97.4Very high47 Ų4747.2 Ų47.249%0.48525%0.254SS..SBendtrans69.5171.2-177.800000114.7
382D91.4Very high97.5Very high178 Ų17846.9 Ų46.995%0.95225%0.251SS*.SBendtrans-97-11.1-178.7-58.7-38.8000113.2
383K93.5Very high97.5Very high147 Ų14741.5 Ų41.564%0.63923%0.228SC*.SBendtrans-127.6156.2179.9-67.7-169.9177.9-171.40111.2
384G96.7Very high97.4Very high12 Ų1242 Ų4212%0.12423%0.231CC..SBendtrans68.6-177.3179.800000114.5P21 T22 K356 F386P21-G384 CarbonylContact O-C 3.5Å; P21-G384 WeakPolarHBondContact O-CA 3.39Å; T22-G384 WeakPolarHBondContact O-CA 3.31Å; T22-G384 PolarHBondContact O-N 2.99Å; K356-G384 PolarHBondContact NZ-O 3.22Å; G384-F386 PolarHBondContact O-N 3.37Å
385Y98.3Very high97.4Very high39 Ų3940 Ų4015%0.15322%0.221CC..SBendtrans-104.240.9-170.3-47.7-50.3000113.1P21 Q350 D352 K353 K356P21-Y385 HydrophobicContact CB-CD2 3.74Å; P21-Y385 HydrophobicContact CB-CE2 4.21Å; P21-Y385 PolarHBondContact O-N 2.91Å; Q350-Y385 WeakPolarHBondContact CB-O 2.96Å; Q350-Y385 WeakPolarHBondContact CG-O 3.25Å; Q350-Y385 PolarHBondContact N-O 2.83Å; Q350-Y385 WeakPolarHBondContact O-CB 3.34Å; D352-Y385 VanDerWaalsContact CA-CD2 3.45Å; K353-Y385 HydrophobicContact CB-CD1 4.18Å; K353-Y385 HydrophobicContact CB-CE1 3.75Å; K356-Y385 HydrophobicContact CD-CD1 4.45Å
386F98.6Very high97.3Very high8 Ų843.4 Ų43.44%0.03524%0.241CC..  trans-74.2143.5-178.8-64-94.2000113.7T22 M337 G338 G348 P349 S379 W380 G384T22-F386 HydrophobicContact CG2-CE2 4.27Å; T22-F386 HydrophobicContact CG2-CZ 4.03Å; M337-F386 HydrophobicContact CB-CD1 4.47Å; G338-F386 WeakPolarHBondContact O-CE1 3.25Å; G338-F386 WeakPolarHBondContact O-CZ 3.45Å; G348-F386 WeakPolarHBondContact O-CD1 3.4Å; P349-F386 HydrophobicContact CB-CD1 4.24Å; P349-F386 HydrophobicContact CB-CD2 4.06Å; P349-F386 HydrophobicContact CB-CE1 4.24Å; P349-F386 HydrophobicContact CB-CE2 4.04Å; P349-F386 HydrophobicContact CB-CG 4.16Å; P349-F386 HydrophobicContact CB-CZ 4.14Å; P349-F386 HydrophobicContact CG-CZ 4.33Å; S379-F386 WeakPolarHBondContact CA-O 3.49Å; W380-F386 HydrophobicContact CB-CB 4.15Å; W380-F386 HydrophobicContact CE3-CB 4.09Å; W380-F386 HydrophobicContact CE3-CD1 4.13Å; W380-F386 HydrophobicContact CE3-CD2 4.32Å; W380-F386 AromaticContact CE3-CG 3.94Å; W380-F386 HydrophobicContact CE3-CG 3.94Å; W380-F386 HydrophobicContact CZ3-CD1 4.42Å; W380-F386 HydrophobicContact CZ3-CE1 4.49Å; W380-F386 HydrophobicContact CZ3-CG 4.45Å; W380-F386 PolarHBondContact N-O 3.25Å; W380-F386 WeakPolarHBondContact O-CB 3.3Å; G384-F386 PolarHBondContact O-N 3.37Å
387I98.6Very high97.1Very high0 Ų044.4 Ų44.40%024%0.24CC..BIsolated β-bridgetrans-132.4134.8171.8-60.7-179.1000107.9Q347 Q350 K356 I359 L360 I363 P409Q347-I387 PolarHBondContact NE2-O 3.17Å; Q350-I387 HydrophobicContact CG-CD1 3.76Å; Q350-I387 HydrophobicContact CG-CG1 3.98Å; K356-I387 HydrophobicContact CB-CD1 4.34Å; K356-I387 HydrophobicContact CG-CD1 3.99Å; K356-I387 HydrophobicContact CG-CG1 4.01Å; I359-I387 HydrophobicContact CB-CD1 3.57Å; I359-I387 HydrophobicContact CD1-CD1 3.88Å; I359-I387 HydrophobicContact CG1-CD1 4.35Å; I359-I387 HydrophobicContact CG2-CD1 3.48Å; I359-I387 VanDerWaalsContact CG2-CD1 3.48Å; I359-I387 HydrophobicContact CG2-CG2 4.46Å; L360-I387 HydrophobicContact CD2-CD1 4.46Å; L360-I387 HydrophobicContact CG-CD1 4.27Å; I363-I387 HydrophobicContact CD1-CG2 4.33Å; I387-P409 HydrophobicContact CB-CG 4.15Å; I387-P409 HydrophobicContact CG2-CG 4.15Å
388K98.5Very high97Very high77 Ų7749.8 Ų49.834%0.33528%0.275SS..  trans-64.9143.3178.1-64.6-176.1-174.8160.50111.3M337 T378 S379 W380 T390M337-K388 HydrophobicContact CE-CG 4.11Å; T378-K388 PolarHBondContact O-N 3.4Å; T378-K388 WeakPolarHBondContact OG1-CD 3.42Å; T378-K388 PolarHBondContact OG1-NZ 3.06Å; S379-K388 WeakPolarHBondContact O-CE 3.07Å; W380-K388 HydrophobicContact CB-CG 3.97Å; K388-T390 PolarHBondContact O-N 3.26Å; K388-T390 VanDerWaalsContact O-N 3.12Å; K388-T390 PolarHBondContact O-OG1 3.25Å
389P98.6Very high97Very high8 Ų847.7 Ų47.75%0.05226%0.261CS..  trans-51.9119.9168.8-22.331.3000110.4F301 A332 R335 G376F301-P389 HydrophobicContact CD1-CB 3.99Å; F301-P389 HydrophobicContact CE1-CB 3.59Å; F301-P389 HydrophobicContact CZ-CB 4.06Å; A332-P389 HydrophobicContact CB-CB 4.02Å; A332-P389 WeakPolarHBondContact O-CB 3.49Å; A332-P389 WeakPolarHBondContact O-CG 3.34Å; R335-P389 HydrophobicContact CB-CG 4.01Å; R335-P389 HydrophobicContact CG-CG 4.47Å; G376-P389 WeakPolarHBondContact CA-O 3.34Å
390T98.9Very high97Very high0 Ų046.3 Ų46.30%025%0.25CC..EExtended strand (participates in β ladder)trans-113.1134-170.7-59.20000110I363 L373 C375 G377 K388 F392 P409 V410 M411I363-T390 HydrophobicContact CD1-CG2 4.36Å; I363-T390 HydrophobicContact CG1-CG2 4.34Å; L373-T390 HydrophobicContact CD1-CG2 3.53Å; C375-T390 WeakPolarHBondContact O-CA 3.45Å; G377-T390 PolarHBondContact N-OG1 3.14Å; K388-T390 PolarHBondContact O-N 3.26Å; K388-T390 VanDerWaalsContact O-N 3.12Å; K388-T390 PolarHBondContact O-OG1 3.25Å; T390-F392 HydrophobicContact CG2-CD2 4.35Å; T390-F392 HydrophobicContact CG2-CE2 4.12Å; T390-P409 PolarHBondContact N-O 3Å; T390-V410 HydrophobicContact CG2-CG1 3.86Å; T390-V410 CarbonylContact O-C 3.55Å; T390-V410 WeakPolarHBondContact O-CA 3.38Å; T390-M411 PolarHBondContact O-N 3.4Å
391V98.8Very high97.1Very high0 Ų041.5 Ų41.50%023%0.232CC..EExtended strand (participates in β ladder)trans-126.4120.8177.2-179.60000109.2F301 V329 A332 L374 C375 M411 I413F301-V391 HydrophobicContact CZ-CG2 4.31Å; V329-V391 HydrophobicContact CG2-CB 4.49Å; V329-V391 HydrophobicContact CG2-CG1 4.32Å; A332-V391 HydrophobicContact CB-CG2 3.73Å; L374-V391 HydrophobicContact CD1-CG1 4.44Å; L374-V391 PolarHBondContact N-O 3.23Å; C375-V391 PolarHBondContact O-N 3.01Å; V391-M411 HydrophobicContact CG2-CB 4.24Å; V391-I413 HydrophobicContact CG1-CD1 3.63Å; V391-I413 HydrophobicContact CG1-CG1 4.29Å
392F98.8Very high97.3Very high0 Ų039.3 Ų39.30%021%0.209CC..EExtended strand (participates in β ladder)trans-101.3134.2165.8-76.6-74.2000109.9I363 K367 A371 K372 L373 T390 V395 V410 M411 I413I363-F392 HydrophobicContact CG1-CE2 4.46Å; I363-F392 HydrophobicContact CG2-CE2 4.41Å; I363-F392 HydrophobicContact CG2-CZ 4.14Å; I363-F392 WeakPolarHBondContact O-CZ 3.31Å; K367-F392 HydrophobicContact CG-CE1 4.15Å; K367-F392 HydrophobicContact CG-CZ 4.25Å; A371-F392 HydrophobicContact CB-CB 4.33Å; A371-F392 HydrophobicContact CB-CD1 3.54Å; A371-F392 HydrophobicContact CB-CE1 4.03Å; A371-F392 HydrophobicContact CB-CG 4.09Å; K372-F392 WeakPolarHBondContact O-CA 3.31Å; L373-F392 HydrophobicContact CB-CD1 4.07Å; L373-F392 HydrophobicContact CB-CE1 3.66Å; L373-F392 HydrophobicContact CB-CZ 4.4Å; L373-F392 HydrophobicContact CD1-CD1 4.34Å; L373-F392 HydrophobicContact CD1-CE1 4Å; L373-F392 HydrophobicContact CD1-CE2 4.43Å; L373-F392 HydrophobicContact CD1-CZ 4.04Å; L373-F392 HydrophobicContact CG-CE1 4.41Å; T390-F392 HydrophobicContact CG2-CD2 4.35Å; T390-F392 HydrophobicContact CG2-CE2 4.12Å; F392-V395 HydrophobicContact CB-CG2 3.63Å; F392-V410 HydrophobicContact CD2-CG1 3.81Å; F392-V410 HydrophobicContact CE2-CG1 3.91Å; F392-M411 PolarHBondContact N-O 3.11Å; F392-I413 PolarHBondContact O-N 3.28Å
393A98.4Very high97.6Very high2 Ų232.9 Ų32.92%0.01717%0.173CC..EExtended strand (participates in β ladder)trans-109.8170165.800000110.5V325 K372 L374 V395V325-A393 HydrophobicContact CG1-CB 4.21Å; V325-A393 HydrophobicContact CG2-CB 4.34Å; K372-A393 WeakPolarHBondContact CB-O 3.45Å; K372-A393 PolarHBondContact N-O 3.05Å; K372-A393 PolarHBondContact O-N 3.41Å; L374-A393 HydrophobicContact CD1-CB 3.51Å; L374-A393 HydrophobicContact CG-CB 4.1Å; A393-V395 PolarHBondContact O-N 2.86Å
394D96.6Very high97.8Very high69 Ų6930 Ų3037%0.36916%0.162SC..SBendtrans57.432.8177.9-50.1-34.7000111.5Y321 K372 I413Y321-D394 WeakPolarHBondContact OH-CA 3.33Å; Y321-D394 PolarHBondContact OH-N 3.3Å; Y321-D394 PolarHBondContact OH-OD1 2.6Å; K372-D394 WeakPolarHBondContact CD-OD2 3.27Å; D394-I413 PolarHBondContact N-O 3.26Å
395V98.2Very high97.9Very high3 Ų330.3 Ų30.32%0.01816%0.16CC..  trans-75132176.6-174.50000108.5A371 F392 A393 M399 V401 A402 Q412 I413 M414A371-V395 HydrophobicContact CB-CG2 4.18Å; F392-V395 HydrophobicContact CB-CG2 3.63Å; A393-V395 PolarHBondContact O-N 2.86Å; V395-M399 HydrophobicContact CB-SD 4.48Å; V395-M399 HydrophobicContact CG1-SD 3.98Å; V395-V401 HydrophobicContact CG1-CG2 4.06Å; V395-A402 HydrophobicContact CG1-CB 3.78Å; V395-Q412 HydrophobicContact CB-CB 4.22Å; V395-Q412 HydrophobicContact CG1-CB 4.13Å; V395-Q412 HydrophobicContact CG1-CG 4.27Å; V395-Q412 HydrophobicContact CG2-CB 3.89Å; V395-Q412 HydrophobicContact CG2-CG 4.17Å; V395-I413 PolarHBondContact N-O 2.99Å; V395-M414 HydrophobicContact CB-CE 4.3Å; V395-M414 HydrophobicContact CB-CG 4.08Å; V395-M414 HydrophobicContact CG1-CE 3.76Å; V395-M414 HydrophobicContact CG1-CG 4.49Å; V395-M414 WeakPolarHBondContact O-CG 3.46Å
396V96.5Very high97.9Very high84 Ų8428.7 Ų28.751%0.50915%0.154SC..  trans-130.2154.7178-63.90000110.5M399V396-M399 HydrophobicContact CG2-CE 3.6Å; V396-M399 HydrophobicContact CG2-CG 4.37Å; V396-M399 HydrophobicContact CG2-SD 4.07Å; V396-M399 PolarHBondContact N-SD 3.34Å; V396-M399 VanDerWaalsContact N-SD 3.45Å; V396-M399 VanDerWaalsContact O-CB 3.23Å; V396-M399 WeakPolarHBondContact O-CB 3.15Å; V396-M399 WeakPolarHBondContact O-CG 3.26Å; V396-M399 PolarHBondContact O-N 3.44Å
397D94.7Very high97.9Very high47 Ų4729.8 Ų29.825%0.25116%0.159SC..THydrogen-bonded Turntrans-69.5144.5166.4-74-21.9000110Q403 N428D397-Q403 VanDerWaalsContact CG-NE2 3.3Å; D397-Q403 PolarHBondContact OD1-NE2 3.23Å; D397-N428 PolarHBondContact OD2-ND2 3.06Å
398P95.8Very high97.9Very high115 Ų11530 Ų3075%0.74716%0.16SC*.THydrogen-bonded Turncis-102.142.82.940.5-35.3000113.2I400P398-I400 PolarHBondContact O-N 3.23Å
399M98Very high97.9Very high19 Ų1926.3 Ų26.39%0.09414%0.144CC..  trans-54.6141177-69170.3175.100110.9E369 A371 V395 V396 V401 A402 Q403E369-M399 HydrophobicContact CB-CG 4.14Å; E369-M399 WeakPolarHBondContact O-CE 3.39Å; E369-M399 WeakPolarHBondContact OE2-CA 3.13Å; E369-M399 WeakPolarHBondContact OE2-CB 3.49Å; A371-M399 HydrophobicContact CB-CE 4.43Å; A371-M399 HydrophobicContact CB-SD 3.87Å; V395-M399 HydrophobicContact CB-SD 4.48Å; V395-M399 HydrophobicContact CG1-SD 3.98Å; V396-M399 HydrophobicContact CG2-CE 3.6Å; V396-M399 HydrophobicContact CG2-CG 4.37Å; V396-M399 HydrophobicContact CG2-SD 4.07Å; V396-M399 PolarHBondContact N-SD 3.34Å; V396-M399 VanDerWaalsContact N-SD 3.45Å; V396-M399 VanDerWaalsContact O-CB 3.23Å; V396-M399 WeakPolarHBondContact O-CB 3.15Å; V396-M399 WeakPolarHBondContact O-CG 3.26Å; V396-M399 PolarHBondContact O-N 3.44Å; M399-V401 HydrophobicContact CB-CG2 4.17Å; M399-V401 PolarHBondContact O-N 3.34Å; M399-A402 HydrophobicContact CB-CB 4.35Å; M399-A402 WeakPolarHBondContact O-CA 3.38Å; M399-A402 WeakPolarHBondContact O-CB 3.48Å; M399-A402 PolarHBondContact O-N 3.5Å; M399-Q403 PolarHBondContact O-N 2.85Å; M399-Q403 VanDerWaalsContact O-N 3.07Å
400I97.8Very high97.9Very high17 Ų1726 Ų269%0.08714%0.142CC..Hα-helixtrans-59.6-37.3-177.8-161178.7000111.7F362 K365 E369 P398 A402 Q403 E404F362-I400 HydrophobicContact CD1-CD1 4.17Å; F362-I400 HydrophobicContact CD1-CG1 4.29Å; F362-I400 HydrophobicContact CD1-CG2 4.43Å; F362-I400 HydrophobicContact CE1-CD1 3.77Å; F362-I400 HydrophobicContact CE1-CG1 3.93Å; K365-I400 HydrophobicContact CB-CG2 3.66Å; K365-I400 HydrophobicContact CD-CD1 3.61Å; K365-I400 HydrophobicContact CD-CG2 4.19Å; E369-I400 WeakPolarHBondContact OE2-CG2 3.26Å; E369-I400 PolarHBondContact OE2-N 2.94Å; P398-I400 PolarHBondContact O-N 3.23Å; I400-A402 PolarHBondContact O-N 3Å; I400-Q403 PolarHBondContact O-N 3.07Å; I400-Q403 VanDerWaalsContact O-N 3.15Å; I400-E404 HydrophobicContact CG1-CB 4.2Å; I400-E404 HydrophobicContact CG1-CG 3.89Å; I400-E404 WeakPolarHBondContact CG1-OE1 3.49Å; I400-E404 PolarHBondContact O-N 3.39Å
401V98.2Very high97.9Very high0 Ų026 Ų260%014%0.142CC..Hα-helixtrans-66.8-22.2176-65.50000112.2K278 F362 A371 V395 M399 I406 Q412K278-V401 WeakPolarHBondContact CE-O 3.41Å; K278-V401 PolarHBondContact NZ-O 2.9Å; F362-V401 WeakPolarHBondContact O-CG1 3.48Å; A371-V401 HydrophobicContact CB-CG2 4.33Å; V395-V401 HydrophobicContact CG1-CG2 4.06Å; M399-V401 HydrophobicContact CB-CG2 4.17Å; M399-V401 PolarHBondContact O-N 3.34Å; V401-I406 HydrophobicContact CB-CD1 4.14Å; V401-I406 HydrophobicContact CG1-CD1 4.06Å; V401-Q412 HydrophobicContact CB-CG 4.04Å; V401-Q412 HydrophobicContact CG2-CG 4.18Å; V401-Q412 VanDerWaalsContact O-CD 3.26Å; V401-Q412 VanDerWaalsContact O-CG 3.3Å; V401-Q412 WeakPolarHBondContact O-CG 3.49Å; V401-Q412 PolarHBondContact O-OE1 3.34Å; V401-Q412 VanDerWaalsContact O-OE1 3.13Å
402A98.1Very high97.9Very high0 Ų026 Ų260%014%0.142CC..Hα-helixtrans-82.6-33.1172.300000112.2K278 R313 V395 M399 I400 M414K278-A402 VanDerWaalsContact CE-C 3.45Å; K278-A402 WeakPolarHBondContact CE-O 3.28Å; K278-A402 VanDerWaalsContact CG-O 3.32Å; K278-A402 WeakPolarHBondContact CG-O 3.18Å; R313-A402 VanDerWaalsContact CD-O 3.29Å; R313-A402 WeakPolarHBondContact CD-O 3.48Å; V395-A402 HydrophobicContact CG1-CB 3.78Å; M399-A402 HydrophobicContact CB-CB 4.35Å; M399-A402 WeakPolarHBondContact O-CA 3.38Å; M399-A402 WeakPolarHBondContact O-CB 3.48Å; M399-A402 PolarHBondContact O-N 3.5Å; I400-A402 PolarHBondContact O-N 3Å; A402-M414 HydrophobicContact CB-CE 3.5Å; A402-M414 VanDerWaalsContact CB-CE 3.5Å
403Q98Very high97.9Very high43 Ų4326 Ų2620%0.20114%0.142CC..Hα-helixtrans-99.2-34.7-169.1-69.9-64.2-43.800114.3D397 M399 I400 N428D397-Q403 VanDerWaalsContact CG-NE2 3.3Å; D397-Q403 PolarHBondContact OD1-NE2 3.23Å; M399-Q403 PolarHBondContact O-N 2.85Å; M399-Q403 VanDerWaalsContact O-N 3.07Å; I400-Q403 PolarHBondContact O-N 3.07Å; I400-Q403 VanDerWaalsContact O-N 3.15Å; Q403-N428 PolarHBondContact NE2-O 2.92Å; Q403-N428 PolarHBondContact OE1-O 3.01Å
404E98Very high97.9Very high88 Ų8826.2 Ų26.241%0.41114%0.143SC..SBendtrans-100.3148-175-67.3-169.8-153.100113.3K278 F362 I400 I406K278-E404 WeakPolarHBondContact CD-O 2.99Å; K278-E404 VanDerWaalsContact CE-O 3.23Å; K278-E404 WeakPolarHBondContact CE-O 3.18Å; K278-E404 PolarHBondContact NZ-O 3.47Å; F362-E404 HydrophobicContact CE1-CB 3.72Å; F362-E404 HydrophobicContact CE1-CG 4.45Å; F362-E404 WeakPolarHBondContact CE1-OE2 3.47Å; F362-E404 HydrophobicContact CZ-CB 4.02Å; F362-E404 VanDerWaalsContact CZ-OE2 3.29Å; F362-E404 WeakPolarHBondContact CZ-OE2 3.42Å; I400-E404 HydrophobicContact CG1-CB 4.2Å; I400-E404 HydrophobicContact CG1-CG 3.89Å; I400-E404 WeakPolarHBondContact CG1-OE1 3.49Å; I400-E404 PolarHBondContact O-N 3.39Å; E404-I406 PolarHBondContact O-N 2.85Å
405E98.4Very high97.9Very high18 Ų1828.3 Ų28.38%0.08415%0.146CC..  trans-74.7106.5175.7-176-177.7-127.500110.4G276 G277 R358 F407G276-E405 WeakPolarHBondContact CA-OE1 3.47Å; G276-E405 WeakPolarHBondContact CA-OE2 3.28Å; G277-E405 PolarHBondContact N-OE1 3.38Å; G277-E405 WeakPolarHBondContact O-CG 3.41Å; R358-E405 PolarHBondContact NH2-O 3.01Å; E405-F407 HydrophobicContact CG-CB 4.14Å; E405-F407 HydrophobicContact CG-CD2 4Å; E405-F407 WeakPolarHBondContact OE1-CD2 3.43Å
406I98.5Very high97.9Very high5 Ų528.3 Ų28.33%0.02615%0.146CC..  trans-73.5-39176.7-57.8175.1000110.7I359 F362 V401 E404 G408 V410I359-I406 HydrophobicContact CB-CG2 4.34Å; I359-I406 HydrophobicContact CG1-CG2 4.08Å; I359-I406 HydrophobicContact CG2-CG2 3.98Å; F362-I406 HydrophobicContact CB-CD1 4.24Å; F362-I406 HydrophobicContact CB-CG1 3.99Å; F362-I406 HydrophobicContact CB-CG2 4.12Å; F362-I406 HydrophobicContact CD1-CG1 4.22Å; F362-I406 HydrophobicContact CD2-CB 4.38Å; F362-I406 HydrophobicContact CD2-CG1 4.23Å; F362-I406 HydrophobicContact CD2-CG2 4.19Å; F362-I406 HydrophobicContact CG-CG1 3.91Å; F362-I406 HydrophobicContact CG-CG2 4.38Å; V401-I406 HydrophobicContact CB-CD1 4.14Å; V401-I406 HydrophobicContact CG1-CD1 4.06Å; E404-I406 PolarHBondContact O-N 2.85Å; I406-G408 VanDerWaalsContact C-N 3.34Å; I406-G408 PolarHBondContact O-N 3.44Å; I406-V410 HydrophobicContact CD1-CB 4.07Å; I406-V410 HydrophobicContact CD1-CG1 4.02Å; I406-V410 HydrophobicContact CG2-CB 4.36Å; I406-V410 HydrophobicContact CG2-CG2 3.99Å
407F98.6Very high97.8Very high31 Ų3129.6 Ų29.614%0.13615%0.15CC..  trans5941.1-178.7-147.2-108.2000113.6W147 N148 G305 Q306 V307 C308 H355 E405W147-F407 AromaticContact CH2-CD1 3.57Å; W147-F407 HydrophobicContact CH2-CD1 3.57Å; W147-F407 AromaticContact CH2-CE1 3.42Å; W147-F407 HydrophobicContact CH2-CE1 3.42Å; W147-F407 VanDerWaalsContact CH2-CE1 3.42Å; W147-F407 AromaticContact CZ2-CD1 3.87Å; W147-F407 HydrophobicContact CZ2-CD1 3.87Å; W147-F407 AromaticContact CZ2-CE1 3.71Å; W147-F407 HydrophobicContact CZ2-CE1 3.71Å; W147-F407 HydrophobicContact CZ3-CE1 4.11Å; N148-F407 HydrophobicContact CB-CE1 4.09Å; N148-F407 HydrophobicContact CB-CZ 4.23Å; N148-F407 WeakPolarHBondContact ND2-CZ 3.27Å; G305-F407 CarbonylContact O-C 3.51Å; G305-F407 VanDerWaalsContact O-C 3.22Å; G305-F407 WeakPolarHBondContact O-CA 3.4Å; Q306-F407 HydrophobicContact CB-CD1 3.97Å; Q306-F407 HydrophobicContact CB-CE1 3.81Å; Q306-F407 HydrophobicContact CG-CD1 4.36Å; V307-F407 VanDerWaalsContact C-CE2 3.4Å; C308-F407 HydrophobicContact CB-CE2 4.42Å; H355-F407 PolarHBondContact CE1-O 3.11Å; H355-F407 AromaticContact NE2-CD1 3.92Å; H355-F407 PolarHBondContact NE2-O 3.3Å; E405-F407 HydrophobicContact CG-CB 4.14Å; E405-F407 HydrophobicContact CG-CD2 4Å; E405-F407 WeakPolarHBondContact OE1-CD2 3.43Å
408G98.6Very high97.7Very high3 Ų331.1 Ų31.13%0.03116%0.161CC..SBendtrans-150.8-178.9-17900000111.5Q304 G305 I406 V410Q304-G408 CarbonylContact O-C 3.55Å; Q304-G408 WeakPolarHBondContact O-CA 3.24Å; G305-G408 PolarHBondContact O-N 3.47Å; I406-G408 VanDerWaalsContact C-N 3.34Å; I406-G408 PolarHBondContact O-N 3.44Å; G408-V410 PolarHBondContact O-N 2.82Å
409P98.6Very high97.6Very high0 Ų028 Ų280%014%0.137CC..SBendtrans-82.563.9-169.533.9-34000110.6F301 Q304 I387 T390F301-P409 HydrophobicContact CD1-CB 3.76Å; F301-P409 HydrophobicContact CE1-CB 4.06Å; F301-P409 WeakPolarHBondContact CE1-O 3.32Å; Q304-P409 WeakPolarHBondContact O-CD 3.49Å; I387-P409 HydrophobicContact CB-CG 4.15Å; I387-P409 HydrophobicContact CG2-CG 4.15Å; T390-P409 PolarHBondContact N-O 3Å
410V98.8Very high97.2Very high1 Ų133.7 Ų33.71%0.00616%0.161CC..EExtended strand (participates in β ladder)trans-132.3110.7-173.3-167.40000109.9I359 I363 T390 F392 I406 G408 Q412I359-V410 HydrophobicContact CG2-CG2 3.85Å; I363-V410 HydrophobicContact CD1-CG2 3.92Å; I363-V410 HydrophobicContact CG1-CG1 4.24Å; I363-V410 HydrophobicContact CG1-CG2 3.95Å; T390-V410 HydrophobicContact CG2-CG1 3.86Å; T390-V410 CarbonylContact O-C 3.55Å; T390-V410 WeakPolarHBondContact O-CA 3.38Å; F392-V410 HydrophobicContact CD2-CG1 3.81Å; F392-V410 HydrophobicContact CE2-CG1 3.91Å; I406-V410 HydrophobicContact CD1-CB 4.07Å; I406-V410 HydrophobicContact CD1-CG1 4.02Å; I406-V410 HydrophobicContact CG2-CB 4.36Å; I406-V410 HydrophobicContact CG2-CG2 3.99Å; G408-V410 PolarHBondContact O-N 2.82Å; V410-Q412 VanDerWaalsContact C-NE2 3.3Å; V410-Q412 PolarHBondContact O-NE2 2.94Å
411M98.7Very high96.9Very high0 Ų035 Ų350%017%0.168CC..EExtended strand (participates in β ladder)trans-91.2134.9-179.4-167.7174.3-88.500110.7A296 L300 F301 V314 T390 V391 F392 I413A296-M411 HydrophobicContact CB-CE 4.49Å; L300-M411 HydrophobicContact CB-CE 4.39Å; L300-M411 HydrophobicContact CD2-CB 3.3Å; L300-M411 HydrophobicContact CD2-CE 3.95Å; L300-M411 HydrophobicContact CD2-CG 3.73Å; F301-M411 HydrophobicContact CD2-CE 4.45Å; F301-M411 HydrophobicContact CE2-CE 3.83Å; F301-M411 HydrophobicContact CZ-CB 4.22Å; V314-M411 HydrophobicContact CG2-CE 4.25Å; V314-M411 HydrophobicContact CG2-CG 3.85Å; V314-M411 HydrophobicContact CG2-SD 4.13Å; T390-M411 PolarHBondContact O-N 3.4Å; V391-M411 HydrophobicContact CG2-CB 4.24Å; F392-M411 PolarHBondContact N-O 3.11Å; M411-I413 HydrophobicContact CG-CG1 3.99Å; M411-I413 HydrophobicContact SD-CD1 4.07Å; M411-I413 HydrophobicContact SD-CG1 4.02Å
412Q98.6Very high96.9Very high0 Ų035 Ų350%017%0.168CC..EExtended strand (participates in β ladder)trans-113.2112.9170.8-65.180.463.300109S312 V314 V395 V401 V410 M414S312-Q412 WeakPolarHBondContact O-CB 3.29Å; S312-Q412 PolarHBondContact O-N 3.25Å; S312-Q412 PolarHBondContact O-OE1 3.22Å; V314-Q412 PolarHBondContact N-O 2.82Å; V395-Q412 HydrophobicContact CB-CB 4.22Å; V395-Q412 HydrophobicContact CG1-CB 4.13Å; V395-Q412 HydrophobicContact CG1-CG 4.27Å; V395-Q412 HydrophobicContact CG2-CB 3.89Å; V395-Q412 HydrophobicContact CG2-CG 4.17Å; V401-Q412 HydrophobicContact CB-CG 4.04Å; V401-Q412 HydrophobicContact CG2-CG 4.18Å; V401-Q412 VanDerWaalsContact O-CD 3.26Å; V401-Q412 VanDerWaalsContact O-CG 3.3Å; V401-Q412 WeakPolarHBondContact O-CG 3.49Å; V401-Q412 PolarHBondContact O-OE1 3.34Å; V401-Q412 VanDerWaalsContact O-OE1 3.13Å; V410-Q412 VanDerWaalsContact C-NE2 3.3Å; V410-Q412 PolarHBondContact O-NE2 2.94Å; Q412-M414 HydrophobicContact CB-CE 4.16Å
413I98.6Very high96.8Very high0 Ų035.7 Ų35.70%017%0.173CC..EExtended strand (participates in β ladder)trans-99.8127.2177.9-50.4175.8000108.9V314 V316 Y321 F324 V325 V391 F392 D394 V395 M411V314-I413 CarbonylContact O-C 3.55Å; V314-I413 WeakPolarHBondContact O-CA 3.42Å; V316-I413 HydrophobicContact CG2-CG2 3.92Å; Y321-I413 HydrophobicContact CD2-CG2 4.39Å; Y321-I413 HydrophobicContact CE2-CG2 3.8Å; F324-I413 HydrophobicContact CD1-CD1 4.18Å; F324-I413 HydrophobicContact CD1-CG2 4.31Å; F324-I413 HydrophobicContact CE1-CD1 4.15Å; V325-I413 HydrophobicContact CG2-CD1 4.07Å; V325-I413 HydrophobicContact CG2-CG2 3.99Å; V391-I413 HydrophobicContact CG1-CD1 3.63Å; V391-I413 HydrophobicContact CG1-CG1 4.29Å; F392-I413 PolarHBondContact O-N 3.28Å; D394-I413 PolarHBondContact N-O 3.26Å; V395-I413 PolarHBondContact N-O 2.99Å; M411-I413 HydrophobicContact CG-CG1 3.99Å; M411-I413 HydrophobicContact SD-CD1 4.07Å; M411-I413 HydrophobicContact SD-CG1 4.02Å
414M98.3Very high96.7Very high8 Ų839.1 Ų39.14%0.03919%0.188CC..EExtended strand (participates in β ladder)trans-125145.3-176.1-54.2177.5-176.900109R313 V314 F315 V316 V395 A402 Q412R313-M414 HydrophobicContact CB-CE 4.07Å; R313-M414 HydrophobicContact CB-SD 4.4Å; R313-M414 HydrophobicContact CG-CE 3.67Å; V314-M414 PolarHBondContact O-N 3.34Å; F315-M414 WeakPolarHBondContact CA-O 3.43Å; F315-M414 HydrophobicContact CD1-CB 3.82Å; F315-M414 HydrophobicContact CD1-SD 4.12Å; F315-M414 HydrophobicContact CE1-CB 3.99Å; F315-M414 HydrophobicContact CE1-CG 4.34Å; F315-M414 HydrophobicContact CE1-SD 3.4Å; F315-M414 WeakPolarHBondContact CE1-SD 3.03Å; F315-M414 HydrophobicContact CE2-SD 4.14Å; F315-M414 HydrophobicContact CG-CB 4.5Å; F315-M414 HydrophobicContact CZ-SD 3.42Å; F315-M414 WeakPolarHBondContact CZ-SD 3.36Å; V316-M414 PolarHBondContact N-O 3.02Å; V395-M414 HydrophobicContact CB-CE 4.3Å; V395-M414 HydrophobicContact CB-CG 4.08Å; V395-M414 HydrophobicContact CG1-CE 3.76Å; V395-M414 HydrophobicContact CG1-CG 4.49Å; V395-M414 WeakPolarHBondContact O-CG 3.46Å; A402-M414 HydrophobicContact CB-CE 3.5Å; A402-M414 VanDerWaalsContact CB-CE 3.5Å; Q412-M414 HydrophobicContact CB-CE 4.16Å
415R97.4Very high96.7Very high113 Ų11338.1 Ų38.143%0.42618%0.183SC..EExtended strand (participates in β ladder)trans-94.3143.7176.2-168.5179.4-65.1167-1.9110.9V316 A318 Y321 D322V316-R415 WeakPolarHBondContact O-CA 3.43Å; A318-R415 HydrophobicContact CB-CG 3.9Å; Y321-R415 HydrophobicContact CD2-CB 3.77Å; Y321-R415 HydrophobicContact CD2-CG 4.04Å; Y321-R415 HydrophobicContact CE2-CB 3.83Å; Y321-R415 HydrophobicContact CG-CB 4.49Å; Y321-R415 HydrophobicContact CG-CG 4.37Å; D322-R415 IonicContact OD1-NH2 2.8Å
416F97.2Very high96.6Very high3 Ų337.4 Ų37.41%0.01318%0.18CC..EExtended strand (participates in β ladder)trans-132.7151.4165.174.4-90.2000111.6I282 F284 F315 V316 E317 A318 L422I282-F416 HydrophobicContact CG2-CE1 4.3Å; I282-F416 HydrophobicContact CG2-CZ 4.41Å; F284-F416 AromaticContact CD1-CE2 3.98Å; F284-F416 HydrophobicContact CD1-CE2 3.98Å; F284-F416 AromaticContact CD1-CZ 3.78Å; F284-F416 HydrophobicContact CD1-CZ 3.78Å; F284-F416 AromaticContact CE1-CE2 3.69Å; F284-F416 HydrophobicContact CE1-CE2 3.69Å; F284-F416 AromaticContact CE1-CZ 3.77Å; F284-F416 HydrophobicContact CE1-CZ 3.77Å; F284-F416 HydrophobicContact CG-CZ 4.31Å; F284-F416 HydrophobicContact CZ-CE2 4.41Å; F284-F416 HydrophobicContact CZ-CZ 4.29Å; F315-F416 HydrophobicContact CB-CD1 3.88Å; F315-F416 HydrophobicContact CB-CE1 4.28Å; V316-F416 WeakPolarHBondContact O-CD1 3.12Å; V316-F416 PolarHBondContact O-N 2.93Å; V316-F416 VanDerWaalsContact O-N 3.08Å; E317-F416 HydrophobicContact CB-CE1 4.04Å; E317-F416 HydrophobicContact CB-CE2 3.95Å; E317-F416 HydrophobicContact CB-CZ 3.59Å; E317-F416 HydrophobicContact CG-CE2 4.02Å; E317-F416 HydrophobicContact CG-CZ 4.18Å; A318-F416 PolarHBondContact N-O 3.32Å; F416-L422 HydrophobicContact CB-CB 4.2Å; F416-L422 HydrophobicContact CB-CD1 4.33Å; F416-L422 HydrophobicContact CD1-CD1 3.84Å; F416-L422 HydrophobicContact CD2-CB 3.92Å; F416-L422 HydrophobicContact CD2-CD1 4.38Å; F416-L422 HydrophobicContact CD2-CD2 4.16Å; F416-L422 HydrophobicContact CD2-CG 4.38Å; F416-L422 HydrophobicContact CE1-CD1 4.17Å; F416-L422 HydrophobicContact CE1-CD2 4.45Å; F416-L422 HydrophobicContact CE2-CD2 3.95Å; F416-L422 HydrophobicContact CG-CB 4.06Å; F416-L422 HydrophobicContact CG-CD1 3.93Å; F416-L422 HydrophobicContact CG-CG 4.39Å; F416-L422 HydrophobicContact CZ-CD2 4.08Å
417D94Very high96.6Very high111 Ų11138.5 Ų38.559%0.59419%0.186SC*.  trans-112.8-31.8-177.8-57.8-70.2000112.8A318A318-D417 WeakPolarHBondContact CB-OD1 3.45Å
418T94Very high96.6Very high79 Ų7941.1 Ų41.149%0.48520%0.201SC..SBendtrans-135.4153.9-177.274.10000111.7K420 D421 L422T418-K420 VanDerWaalsContact C-N 3.29Å; T418-K420 PolarHBondContact O-N 3.31Å; T418-D421 PolarHBondContact O-N 3.44Å; T418-D421 WeakPolarHBondContact OG1-CB 3.12Å; T418-D421 PolarHBondContact OG1-N 3.15Å; T418-L422 WeakPolarHBondContact O-CB 3.46Å; T418-L422 PolarHBondContact O-N 2.94Å
419M93.1Very high96.5Very high48 Ų4841.7 Ų41.724%0.23620%0.204CC..Hα-helixtrans-59.2-38.3177.7-174.86676.600112.8F284 L422 V423 K444 Y447 V448F284-M419 HydrophobicContact CE1-CE 3.57Å; F284-M419 HydrophobicContact CE1-SD 4.25Å; F284-M419 HydrophobicContact CE2-CE 4.27Å; F284-M419 HydrophobicContact CZ-CE 3.28Å; F284-M419 HydrophobicContact CZ-SD 3.71Å; M419-L422 HydrophobicContact SD-CD2 4.03Å; M419-V423 WeakPolarHBondContact O-CG2 3.34Å; M419-V423 PolarHBondContact O-N 2.92Å; M419-V423 VanDerWaalsContact O-N 3.1Å; M419-K444 HydrophobicContact CE-CB 3.89Å; M419-K444 HydrophobicContact CE-CD 4.31Å; M419-K444 HydrophobicContact CE-CG 3.8Å; M419-Y447 HydrophobicContact CE-CD1 4.39Å; M419-Y447 HydrophobicContact CG-CD1 3.5Å; M419-Y447 HydrophobicContact CG-CE1 3.37Å; M419-Y447 HydrophobicContact SD-CD1 3.7Å; M419-Y447 HydrophobicContact SD-CE1 4.07Å; M419-V448 HydrophobicContact CE-CG2 4.11Å; M419-V448 HydrophobicContact SD-CG2 3.55Å; M419-V448 VanDerWaalsContact SD-CG2 3.55Å
420K90.7Very high96.5Very high140 Ų14045.9 Ų45.961%0.60923%0.226SC*.Hα-helixtrans-65.7-51.2-179.5-176.8-177.9173.9-1740111.3T418 L422 V423 E424T418-K420 VanDerWaalsContact C-N 3.29Å; T418-K420 PolarHBondContact O-N 3.31Å; K420-L422 VanDerWaalsContact C-N 3.3Å; K420-L422 PolarHBondContact O-N 3.22Å; K420-V423 PolarHBondContact O-N 3.22Å; K420-E424 WeakPolarHBondContact CE-OE1 3.31Å; K420-E424 PolarHBondContact O-N 2.79Å; K420-E424 VanDerWaalsContact O-N 3.15Å
421D91.4Very high96.5Very high43 Ų4347.2 Ų47.223%0.2323%0.231CC..Hα-helixtrans-58.7-42.4177.1173.463.7000111.7T418 E424 K425T418-D421 PolarHBondContact O-N 3.44Å; T418-D421 WeakPolarHBondContact OG1-CB 3.12Å; T418-D421 PolarHBondContact OG1-N 3.15Å; D421-E424 PolarHBondContact O-N 2.97Å; D421-K425 VanDerWaalsContact CG-NZ 3.26Å; D421-K425 WeakPolarHBondContact O-CB 3.41Å; D421-K425 WeakPolarHBondContact O-CG 3.34Å; D421-K425 PolarHBondContact O-N 3.16Å; D421-K425 WeakPolarHBondContact OD1-CE 3.49Å; D421-K425 IonicContact OD1-NZ 2.83Å; D421-K425 PolarHBondContact OD1-NZ 2.9Å; D421-K425 WeakPolarHBondContact OD2-CE 3.35Å; D421-K425 IonicContact OD2-NZ 3.98Å; D421-K425 PolarHBondContact OD2-NZ 2.87Å
422L96.3Very high96.5Very high0 Ų047.5 Ų47.50%023%0.234CC..Hα-helixtrans-56.5-51.9175.6168.667.5000112.5I282 F284 F315 F416 T418 M419 K420 E424 K425 A426 V448I282-L422 HydrophobicContact CD1-CD1 4.07Å; I282-L422 HydrophobicContact CD1-CD2 4.4Å; I282-L422 HydrophobicContact CD1-CG 4.36Å; I282-L422 HydrophobicContact CG1-CD1 4.02Å; I282-L422 HydrophobicContact CG2-CD1 3.91Å; I282-L422 HydrophobicContact CG2-CD2 3.57Å; I282-L422 HydrophobicContact CG2-CG 4.3Å; F284-L422 HydrophobicContact CE1-CD2 4.13Å; F284-L422 HydrophobicContact CE2-CD2 4.3Å; F284-L422 HydrophobicContact CZ-CD2 3.54Å; F315-L422 HydrophobicContact CB-CD1 3.71Å; F315-L422 HydrophobicContact CD1-CD1 4.23Å; F315-L422 HydrophobicContact CG-CD1 3.97Å; F416-L422 HydrophobicContact CB-CB 4.2Å; F416-L422 HydrophobicContact CB-CD1 4.33Å; F416-L422 HydrophobicContact CD1-CD1 3.84Å; F416-L422 HydrophobicContact CD2-CB 3.92Å; F416-L422 HydrophobicContact CD2-CD1 4.38Å; F416-L422 HydrophobicContact CD2-CD2 4.16Å; F416-L422 HydrophobicContact CD2-CG 4.38Å; F416-L422 HydrophobicContact CE1-CD1 4.17Å; F416-L422 HydrophobicContact CE1-CD2 4.45Å; F416-L422 HydrophobicContact CE2-CD2 3.95Å; F416-L422 HydrophobicContact CG-CB 4.06Å; F416-L422 HydrophobicContact CG-CD1 3.93Å; F416-L422 HydrophobicContact CG-CG 4.39Å; F416-L422 HydrophobicContact CZ-CD2 4.08Å; T418-L422 WeakPolarHBondContact O-CB 3.46Å; T418-L422 PolarHBondContact O-N 2.94Å; M419-L422 HydrophobicContact SD-CD2 4.03Å; K420-L422 VanDerWaalsContact C-N 3.3Å; K420-L422 PolarHBondContact O-N 3.22Å; L422-E424 PolarHBondContact O-N 2.77Å; L422-K425 PolarHBondContact O-N 2.85Å; L422-A426 WeakPolarHBondContact O-CB 3.38Å; L422-A426 PolarHBondContact O-N 3.05Å; L422-V448 HydrophobicContact CD2-CG2 4.46Å
423V97.1Very high96.5Very high16 Ų1647.5 Ų47.510%0.09723%0.234CC..Hα-helixtrans-64.8-41-177.3168.60000111.2M419 K420 N427 Y447 N451 I452M419-V423 WeakPolarHBondContact O-CG2 3.34Å; M419-V423 PolarHBondContact O-N 2.92Å; M419-V423 VanDerWaalsContact O-N 3.1Å; K420-V423 PolarHBondContact O-N 3.22Å; V423-N427 WeakPolarHBondContact O-CB 3.47Å; V423-N427 PolarHBondContact O-N 3.34Å; V423-N427 PolarHBondContact O-ND2 3.32Å; V423-Y447 HydrophobicContact CG2-CE1 4.04Å; V423-N451 HydrophobicContact CG1-CB 3.9Å; V423-N451 HydrophobicContact CG2-CB 4.31Å; V423-I452 HydrophobicContact CG1-CD1 4.48Å; V423-I452 HydrophobicContact CG2-CD1 4.39Å
424E96.2Very high96.5Very high114 Ų11447.6 Ų47.653%0.53323%0.234SC..Hα-helixtrans-60.5-50.7176.5-72.6176.3-171.500110.8K420 D421 L422 N427 N428K420-E424 WeakPolarHBondContact CE-OE1 3.31Å; K420-E424 PolarHBondContact O-N 2.79Å; K420-E424 VanDerWaalsContact O-N 3.15Å; D421-E424 PolarHBondContact O-N 2.97Å; L422-E424 PolarHBondContact O-N 2.77Å; E424-N427 PolarHBondContact O-N 2.79Å; E424-N428 WeakPolarHBondContact O-CB 3.32Å; E424-N428 PolarHBondContact O-N 3.13Å
425K96.8Very high96.5Very high67 Ų6747.2 Ų47.229%0.29123%0.232SC..Hα-helixtrans-63.8-43.6177.7-72.8171.7173.1164.90113.2R313 F315 D421 L422 N427 N428R313-K425 PolarHBondContact NH1-O 3.08Å; F315-K425 HydrophobicContact CE1-CB 3.86Å; F315-K425 HydrophobicContact CZ-CB 4.31Å; D421-K425 VanDerWaalsContact CG-NZ 3.26Å; D421-K425 WeakPolarHBondContact O-CB 3.41Å; D421-K425 WeakPolarHBondContact O-CG 3.34Å; D421-K425 PolarHBondContact O-N 3.16Å; D421-K425 WeakPolarHBondContact OD1-CE 3.49Å; D421-K425 IonicContact OD1-NZ 2.83Å; D421-K425 PolarHBondContact OD1-NZ 2.9Å; D421-K425 WeakPolarHBondContact OD2-CE 3.35Å; D421-K425 IonicContact OD2-NZ 3.98Å; D421-K425 PolarHBondContact OD2-NZ 2.87Å; L422-K425 PolarHBondContact O-N 2.85Å; K425-N427 VanDerWaalsContact C-N 3.26Å; K425-N427 PolarHBondContact O-N 3.47Å; K425-N428 WeakPolarHBondContact O-CB 3.25Å; K425-N428 PolarHBondContact O-N 2.99Å; K425-N428 VanDerWaalsContact O-N 3.13Å
426A98Very high96.5Very high3 Ų341.8 Ų41.83%0.02521%0.212CC..Hα-helixtrans-63.5-34.8179.100000111.5P280 I282 R313 F315 L422 I452P280-A426 HydrophobicContact CB-CB 3.97Å; P280-A426 HydrophobicContact CG-CB 4.16Å; I282-A426 HydrophobicContact CD1-CB 4.4Å; R313-A426 PolarHBondContact NH2-O 2.85Å; F315-A426 HydrophobicContact CE2-CB 4.36Å; L422-A426 WeakPolarHBondContact O-CB 3.38Å; L422-A426 PolarHBondContact O-N 3.05Å; A426-I452 HydrophobicContact CB-CD1 3.42Å; A426-I452 VanDerWaalsContact CB-CD1 3.42Å
427N98.2Very high96.6Very high28 Ų2841.7 Ų41.715%0.1521%0.211CC..Hα-helixtrans-83.7-13.7174.8-74-33.8000114.4V423 E424 K425 T429 N451 Q453 K475V423-N427 WeakPolarHBondContact O-CB 3.47Å; V423-N427 PolarHBondContact O-N 3.34Å; V423-N427 PolarHBondContact O-ND2 3.32Å; E424-N427 PolarHBondContact O-N 2.79Å; K425-N427 VanDerWaalsContact C-N 3.26Å; K425-N427 PolarHBondContact O-N 3.47Å; N427-T429 PolarHBondContact O-N 3.24Å; N427-N451 PolarHBondContact ND2-O 3.31Å; N427-Q453 PolarHBondContact OD1-N 3.49Å; N427-K475 PolarHBondContact O-NZ 3.36Å
428N97.7Very high96.8Very high87 Ų8736.6 Ų36.647%0.46518%0.184SC..  trans-7566.3179.6-172.138.4000112.4D397 Q403 E424 K425D397-N428 PolarHBondContact OD2-ND2 3.06Å; Q403-N428 PolarHBondContact NE2-O 2.92Å; Q403-N428 PolarHBondContact OE1-O 3.01Å; E424-N428 WeakPolarHBondContact O-CB 3.32Å; E424-N428 PolarHBondContact O-N 3.13Å; K425-N428 WeakPolarHBondContact O-CB 3.25Å; K425-N428 PolarHBondContact O-N 2.99Å; K425-N428 VanDerWaalsContact O-N 3.13Å
429T97.9Very high97Very high15 Ų1533 Ų339%0.09216%0.162CC..SBendtrans-158.4155.3173.4-179.30000108.9N427 Y431 K475N427-T429 PolarHBondContact O-N 3.24Å; T429-Y431 WeakPolarHBondContact CG2-O 3.3Å; T429-Y431 PolarHBondContact O-N 3.5Å; T429-Y431 WeakPolarHBondContact OG1-CD2 3.45Å; T429-Y431 PolarHBondContact OG1-N 2.93Å; T429-K475 PolarHBondContact O-NZ 3.01Å
430I97.9Very high97.2Very high87 Ų8738 Ų3845%0.44618%0.183SC..SBendtrans-69-16.7175.266.1170.1000112.8K475 M476I430-K475 WeakPolarHBondContact O-CB 3.32Å; I430-M476 HydrophobicContact CB-CB 4.47Å; I430-M476 HydrophobicContact CB-CG 4.25Å; I430-M476 HydrophobicContact CB-SD 3.92Å; I430-M476 HydrophobicContact CD1-SD 3.99Å; I430-M476 HydrophobicContact CG1-SD 4.43Å; I430-M476 HydrophobicContact CG2-SD 4.39Å; I430-M476 WeakPolarHBondContact O-CB 3.47Å; I430-M476 PolarHBondContact O-N 2.94Å
431Y98.6Very high97.6Very high29 Ų2934.3 Ų34.311%0.11417%0.169CC..  trans-91.1164.2-176-60.1-71.8000112.9T253 G276 K278 T429 K475 S477T253-Y431 WeakPolarHBondContact OG1-CE1 3.29Å; G276-Y431 WeakPolarHBondContact O-CD1 3.47Å; K278-Y431 HydrophobicContact CB-CD2 3.51Å; K278-Y431 HydrophobicContact CB-CE2 4.25Å; K278-Y431 HydrophobicContact CB-CG 4.19Å; T429-Y431 WeakPolarHBondContact CG2-O 3.3Å; T429-Y431 PolarHBondContact O-N 3.5Å; T429-Y431 WeakPolarHBondContact OG1-CD2 3.45Å; T429-Y431 PolarHBondContact OG1-N 2.93Å; Y431-K475 WeakPolarHBondContact O-CD 3.29Å; Y431-K475 PolarHBondContact O-NZ 3.18Å; Y431-S477 WeakPolarHBondContact CA-OG 3.1Å; Y431-S477 WeakPolarHBondContact CB-OG 3.16Å
432G98.5Very high97.9Very high6 Ų637.9 Ų37.96%0.06219%0.187CC..  trans-166.241.9179.200000113.1Q453 A454 G455 Y474 S477G432-Q453 VanDerWaalsContact CA-O 3.26Å; G432-Q453 WeakPolarHBondContact CA-O 3.18Å; G432-A454 WeakPolarHBondContact O-CA 3.24Å; G432-G455 PolarHBondContact O-N 3.1Å; G432-Y474 WeakPolarHBondContact O-CB 3.34Å; G432-Y474 PolarHBondContact O-N 3.44Å; G432-S477 PolarHBondContact N-OG 2.98Å
433L98.5Very high98Very high1 Ų143.7 Ų43.71%0.00522%0.218CC..SBendtrans-77.5-64-176.1-169.860.1000112.8C308 T309 G455 T456 F471 S477C308-L433 HydrophobicContact CB-CD2 3.5Å; C308-L433 VanDerWaalsContact CB-CD2 3.5Å; C308-L433 WeakPolarHBondContact O-CD2 3.24Å; T309-L433 HydrophobicContact CG2-CD2 3.84Å; T309-L433 HydrophobicContact CG2-CG 4.12Å; L433-G455 VanDerWaalsContact O-CA 3.28Å; L433-G455 WeakPolarHBondContact O-CA 3.33Å; L433-G455 PolarHBondContact O-N 3.24Å; L433-T456 PolarHBondContact O-N 2.76Å; L433-F471 HydrophobicContact CD1-CE1 4Å; L433-F471 HydrophobicContact CD1-CE2 4.5Å; L433-F471 HydrophobicContact CD1-CZ 3.77Å; L433-F471 HydrophobicContact CD2-CZ 3.96Å; L433-F471 HydrophobicContact CG-CZ 3.84Å; L433-S477 PolarHBondContact N-OG 2.8Å
434A98.4Very high98Very high1 Ų145.5 Ų45.51%0.00823%0.225CC..EExtended strand (participates in β ladder)trans-139.7165.2-178.200000112.1S279 P280 T309 T456 W458S279-A434 WeakPolarHBondContact CA-O 3.39Å; S279-A434 WeakPolarHBondContact CB-O 3.34Å; S279-A434 PolarHBondContact OG-N 2.93Å; S279-A434 PolarHBondContact OG-O 2.98Å; P280-A434 WeakPolarHBondContact CD-O 3.32Å; T309-A434 HydrophobicContact CG2-CB 3.68Å; A434-T456 CarbonylContact C-O 3.54Å; A434-T456 WeakPolarHBondContact CA-O 3.44Å; A434-W458 HydrophobicContact CB-CE3 4.43Å; A434-W458 HydrophobicContact CB-CH2 3.68Å; A434-W458 HydrophobicContact CB-CZ3 3.56Å
435A98.7Very high98.1Very high0 Ų040.3 Ų40.30%020%0.201CC..EExtended strand (participates in β ladder)trans-148.6160172.300000111.1P280 I452 A454 T456 V457 W458P280-A435 HydrophobicContact CG-CB 3.75Å; P280-A435 CarbonylContact O-C 3.58Å; P280-A435 VanDerWaalsContact O-CA 3.24Å; P280-A435 WeakPolarHBondContact O-CA 3.35Å; A435-I452 HydrophobicContact CB-CG2 3.77Å; A435-A454 HydrophobicContact CB-CB 4Å; A435-T456 PolarHBondContact N-O 3.12Å; A435-V457 HydrophobicContact CB-CG1 4.33Å; A435-V457 HydrophobicContact CB-CG2 4.28Å; A435-V457 WeakPolarHBondContact O-CA 3.49Å; A435-W458 PolarHBondContact O-N 2.89Å
436G98.3Very high98.1Very high0 Ų041.5 Ų41.50%021%0.21CC..EExtended strand (participates in β ladder)trans-129.3148.8170.800000111.6P280 I282 W458P280-G436 PolarHBondContact O-N 2.95Å; I282-G436 WeakPolarHBondContact CB-O 3.45Å; I282-G436 PolarHBondContact N-O 3.02Å; G436-W458 CarbonylContact C-O 3.57Å; G436-W458 WeakPolarHBondContact CA-O 3.37Å
437V98.3Very high98.1Very high0 Ų046.4 Ų46.40%023%0.229CC..EExtended strand (participates in β ladder)trans-138132.4173.7610000111I282 F284 T439 V448 V457 W458 V459 N460I282-V437 HydrophobicContact CB-CB 4.47Å; I282-V437 HydrophobicContact CB-CG2 4.43Å; I282-V437 HydrophobicContact CG2-CG2 4.35Å; I282-V437 CarbonylContact O-C 3.49Å; I282-V437 WeakPolarHBondContact O-CA 3.49Å; F284-V437 HydrophobicContact CD2-CG2 4.07Å; F284-V437 HydrophobicContact CE2-CG2 3.74Å; V437-T439 HydrophobicContact CG2-CG2 4.27Å; V437-V448 HydrophobicContact CB-CB 4.48Å; V437-V448 HydrophobicContact CB-CG1 4.01Å; V437-V448 HydrophobicContact CG1-CG1 4.47Å; V437-V448 HydrophobicContact CG2-CB 4.14Å; V437-V448 HydrophobicContact CG2-CG1 4.06Å; V437-V448 HydrophobicContact CG2-CG2 4.27Å; V437-V457 HydrophobicContact CG1-CG1 4.37Å; V437-W458 PolarHBondContact N-O 3.1Å; V437-V459 HydrophobicContact CG1-CB 4.22Å; V437-V459 HydrophobicContact CG1-CG1 4.32Å; V437-V459 HydrophobicContact CG1-CG2 3.73Å; V437-V459 CarbonylContact O-C 3.58Å; V437-V459 WeakPolarHBondContact O-CA 3.28Å; V437-N460 PolarHBondContact O-N 3.34Å
438F98.5Very high98.1Very high5 Ų545.1 Ų45.12%0.02222%0.222CC..EExtended strand (participates in β ladder)trans-121.7117.1-178.9-68.1-96.9000109.9N281 I282 I283 F284 A287 A292 Q295 N460 C461 Y462N281-F438 WeakPolarHBondContact OD1-CD2 3.45Å; N281-F438 WeakPolarHBondContact OD1-CE2 3.42Å; I282-F438 PolarHBondContact O-N 3.46Å; I283-F438 HydrophobicContact CD1-CB 3.96Å; I283-F438 HydrophobicContact CD1-CD2 3.43Å; I283-F438 VanDerWaalsContact CD1-CD2 3.43Å; I283-F438 HydrophobicContact CD1-CE2 4.21Å; I283-F438 HydrophobicContact CD1-CG 3.85Å; F284-F438 PolarHBondContact N-O 3.32Å; A287-F438 HydrophobicContact CB-CB 4.07Å; A292-F438 HydrophobicContact CB-CB 4.04Å; A292-F438 HydrophobicContact CB-CD1 3.99Å; A292-F438 HydrophobicContact CB-CG 4.08Å; Q295-F438 HydrophobicContact CB-CE1 3.51Å; Q295-F438 HydrophobicContact CB-CE2 4.46Å; Q295-F438 HydrophobicContact CB-CZ 3.43Å; Q295-F438 VanDerWaalsContact CB-CZ 3.43Å; Q295-F438 HydrophobicContact CG-CE1 3.75Å; Q295-F438 HydrophobicContact CG-CZ 4.08Å; F438-N460 VanDerWaalsContact CA-OD1 3.29Å; F438-N460 WeakPolarHBondContact CA-OD1 3.37Å; F438-C461 WeakPolarHBondContact CZ-O 3.39Å; F438-Y462 HydrophobicContact CE2-CD2 4.41Å
439T98.3Very high98.1Very high2 Ų242.3 Ų42.31%0.01221%0.211CC..  trans-168.9153.3-177.7-179.40000109.8F284 D286 V437 D441 K444 A445 N460F284-T439 HydrophobicContact CD2-CG2 4.31Å; D286-T439 VanDerWaalsContact CG-OG1 3.27Å; D286-T439 PolarHBondContact OD1-OG1 2.81Å; D286-T439 PolarHBondContact OD2-OG1 3.09Å; V437-T439 HydrophobicContact CG2-CG2 4.27Å; T439-D441 VanDerWaalsContact CG2-O 3.25Å; T439-D441 WeakPolarHBondContact CG2-O 3.36Å; T439-D441 PolarHBondContact OG1-N 3.24Å; T439-D441 VanDerWaalsContact OG1-N 3.11Å; T439-K444 HydrophobicContact CG2-CB 4.18Å; T439-A445 HydrophobicContact CG2-CB 3.75Å; T439-N460 PolarHBondContact N-OD1 3.04Å; T439-N460 PolarHBondContact O-ND2 3.29Å; T439-N460 PolarHBondContact O-OD1 2.66Å; T439-N460 VanDerWaalsContact O-OD1 3.08Å
440K98.2Very high98.1Very high155 Ų15547.7 Ų47.767%0.67424%0.239SC*.SBendtrans-89-13.1170.1-66.9177.9-168.81740111.7D286D286-K440 WeakPolarHBondContact O-CD 3.41Å; D286-K440 VanDerWaalsContact O-CE 3.25Å; D286-K440 WeakPolarHBondContact O-CE 3.08Å; D286-K440 WeakPolarHBondContact O-CG 3.46Å; D286-K440 WeakPolarHBondContact OD2-CA 3.47Å; D286-K440 PolarHBondContact OD2-N 3.18Å
441D98Very high98.1Very high61 Ų6146.8 Ų46.833%0.32624%0.235SC..  trans-87.4112.5178.2-173-29.6000111.4D286 T439 D443 K444 A445D286-D441 PolarHBondContact OD2-N 3.49Å; D286-D441 VanDerWaalsContact OD2-N 3.08Å; T439-D441 VanDerWaalsContact CG2-O 3.25Å; T439-D441 WeakPolarHBondContact CG2-O 3.36Å; T439-D441 PolarHBondContact OG1-N 3.24Å; T439-D441 VanDerWaalsContact OG1-N 3.11Å; D441-D443 VanDerWaalsContact C-N 3.31Å; D441-D443 PolarHBondContact O-N 3.32Å; D441-D443 WeakPolarHBondContact OD1-CA 3.32Å; D441-D443 WeakPolarHBondContact OD1-CB 3.45Å; D441-D443 PolarHBondContact OD1-N 3.29Å; D441-K444 HydrophobicContact CB-CB 4.1Å; D441-K444 HydrophobicContact CB-CD 3.9Å; D441-K444 HydrophobicContact CB-CG 3.91Å; D441-K444 PolarHBondContact O-N 3.48Å; D441-K444 PolarHBondContact OD1-N 3.34Å; D441-K444 WeakPolarHBondContact OD2-CE 3.46Å; D441-A445 PolarHBondContact O-N 3.14Å
442I97.4Very high98Very high119 Ų11945.9 Ų45.961%0.6123%0.232SC*.Hα-helixtrans-67.4-30.8-179.4-166.4163.7000112.8A445 L446I442-A445 PolarHBondContact O-N 2.59Å; I442-L446 HydrophobicContact CG1-CD1 4.02Å; I442-L446 HydrophobicContact CG1-CG 4.17Å; I442-L446 WeakPolarHBondContact O-CB 3.33Å; I442-L446 VanDerWaalsContact O-CG 3.29Å; I442-L446 WeakPolarHBondContact O-CG 3.32Å; I442-L446 PolarHBondContact O-N 2.78Å
443D97.9Very high98Very high122 Ų12250 Ų5065%0.65225%0.25SS*.Hα-helixtrans-69.5-40.4178.8-70.1-31.7000109.9D441 Y447D441-D443 VanDerWaalsContact C-N 3.31Å; D441-D443 PolarHBondContact O-N 3.32Å; D441-D443 WeakPolarHBondContact OD1-CA 3.32Å; D441-D443 WeakPolarHBondContact OD1-CB 3.45Å; D441-D443 PolarHBondContact OD1-N 3.29Å; D443-Y447 WeakPolarHBondContact O-CB 3.4Å; D443-Y447 PolarHBondContact O-N 3.33Å
444K97.6Very high98Very high54 Ų5450.4 Ų50.424%0.23525%0.254CS..Hα-helixtrans-61.5-47.9171.1-68.3-175.5-159.91730111.6F284 D286 M419 T439 D441 L446 Y447 V448F284-K444 HydrophobicContact CD1-CD 3.89Å; F284-K444 HydrophobicContact CE1-CD 4.09Å; F284-K444 HydrophobicContact CG-CD 4.14Å; D286-K444 IonicContact OD1-NZ 2.7Å; D286-K444 PolarHBondContact OD1-NZ 3.07Å; M419-K444 HydrophobicContact CE-CB 3.89Å; M419-K444 HydrophobicContact CE-CD 4.31Å; M419-K444 HydrophobicContact CE-CG 3.8Å; T439-K444 HydrophobicContact CG2-CB 4.18Å; D441-K444 HydrophobicContact CB-CB 4.1Å; D441-K444 HydrophobicContact CB-CD 3.9Å; D441-K444 HydrophobicContact CB-CG 3.91Å; D441-K444 PolarHBondContact O-N 3.48Å; D441-K444 PolarHBondContact OD1-N 3.34Å; D441-K444 WeakPolarHBondContact OD2-CE 3.46Å; K444-L446 PolarHBondContact O-N 3.47Å; K444-Y447 PolarHBondContact O-N 3.38Å; K444-V448 WeakPolarHBondContact O-CG2 3Å; K444-V448 PolarHBondContact O-N 3.14Å
445A97.9Very high98Very high5 Ų551.5 Ų51.54%0.04127%0.265CS..Hα-helixtrans-58.4-48.7-179.200000111.6T439 D441 I442 V448 A449 V459T439-A445 HydrophobicContact CG2-CB 3.75Å; D441-A445 PolarHBondContact O-N 3.14Å; I442-A445 PolarHBondContact O-N 2.59Å; A445-V448 PolarHBondContact O-N 3.26Å; A445-A449 VanDerWaalsContact O-CB 3.28Å; A445-A449 WeakPolarHBondContact O-CB 3.33Å; A445-A449 PolarHBondContact O-N 3.17Å; A445-V459 HydrophobicContact CB-CG1 3.69Å; A445-V459 HydrophobicContact CB-CG2 4.36Å
446L97.7Very high98Very high91 Ų9153 Ų5348%0.47627%0.274SS..Hα-helixtrans-67.8-39.1178.7-69176.5000111.9I442 K444 A449 N450I442-L446 HydrophobicContact CG1-CD1 4.02Å; I442-L446 HydrophobicContact CG1-CG 4.17Å; I442-L446 WeakPolarHBondContact O-CB 3.33Å; I442-L446 VanDerWaalsContact O-CG 3.29Å; I442-L446 WeakPolarHBondContact O-CG 3.32Å; I442-L446 PolarHBondContact O-N 2.78Å; K444-L446 PolarHBondContact O-N 3.47Å; L446-A449 PolarHBondContact O-N 3.18Å; L446-N450 WeakPolarHBondContact O-CB 3.48Å; L446-N450 PolarHBondContact O-N 3.03Å; L446-N450 PolarHBondContact O-ND2 2.89Å
447Y97.8Very high98Very high106 Ų10654.9 Ų54.942%0.41629%0.285SS..Hα-helixtrans-59.7-49.5175.8-176.7-88.1000111.1M419 V423 D443 K444 N450 N451M419-Y447 HydrophobicContact CE-CD1 4.39Å; M419-Y447 HydrophobicContact CG-CD1 3.5Å; M419-Y447 HydrophobicContact CG-CE1 3.37Å; M419-Y447 HydrophobicContact SD-CD1 3.7Å; M419-Y447 HydrophobicContact SD-CE1 4.07Å; V423-Y447 HydrophobicContact CG2-CE1 4.04Å; D443-Y447 WeakPolarHBondContact O-CB 3.4Å; D443-Y447 PolarHBondContact O-N 3.33Å; K444-Y447 PolarHBondContact O-N 3.38Å; Y447-N450 PolarHBondContact O-N 3.25Å; Y447-N451 WeakPolarHBondContact O-CB 3.43Å; Y447-N451 PolarHBondContact O-N 3.26Å; Y447-N451 VanDerWaalsContact O-N 3.17Å; Y447-N451 PolarHBondContact O-ND2 2.95Å
448V97.6Very high98Very high1 Ų155.6 Ų55.61%0.00629%0.288CS..Hα-helixtrans-61.6-49.6176.9173.10000110.5I282 F284 M419 L422 V437 K444 A445 N450 N451 I452I282-V448 HydrophobicContact CD1-CG1 3.62Å; F284-V448 HydrophobicContact CE2-CG2 3.99Å; F284-V448 HydrophobicContact CZ-CG2 3.99Å; M419-V448 HydrophobicContact CE-CG2 4.11Å; M419-V448 HydrophobicContact SD-CG2 3.55Å; M419-V448 VanDerWaalsContact SD-CG2 3.55Å; L422-V448 HydrophobicContact CD2-CG2 4.46Å; V437-V448 HydrophobicContact CB-CB 4.48Å; V437-V448 HydrophobicContact CB-CG1 4.01Å; V437-V448 HydrophobicContact CG1-CG1 4.47Å; V437-V448 HydrophobicContact CG2-CB 4.14Å; V437-V448 HydrophobicContact CG2-CG1 4.06Å; V437-V448 HydrophobicContact CG2-CG2 4.27Å; K444-V448 WeakPolarHBondContact O-CG2 3Å; K444-V448 PolarHBondContact O-N 3.14Å; A445-V448 PolarHBondContact O-N 3.26Å; V448-N450 VanDerWaalsContact C-N 3.25Å; V448-N450 PolarHBondContact O-N 2.86Å; V448-N451 PolarHBondContact O-N 3.15Å; V448-N451 VanDerWaalsContact O-N 3.08Å; V448-I452 HydrophobicContact CG1-CG1 3.64Å; V448-I452 WeakPolarHBondContact O-CG1 2.99Å; V448-I452 PolarHBondContact O-N 3.01Å
449A97.7Very high98Very high28 Ų2858.3 Ų58.323%0.23131%0.305CS..Hα-helixtrans-59-34.2-177.800000113.7A445 L446 V457A445-A449 VanDerWaalsContact O-CB 3.28Å; A445-A449 WeakPolarHBondContact O-CB 3.33Å; A445-A449 PolarHBondContact O-N 3.17Å; L446-A449 PolarHBondContact O-N 3.18Å; A449-V457 HydrophobicContact CB-CB 4.28Å; A449-V457 HydrophobicContact CB-CG1 4.01Å
450N97.6Very high97.9Very high129 Ų12962.1 Ų62.169%0.6933%0.325SS*.Hα-helixtrans-84-18.5178.4-75.1-76000114.1L446 Y447 V448L446-N450 WeakPolarHBondContact O-CB 3.48Å; L446-N450 PolarHBondContact O-N 3.03Å; L446-N450 PolarHBondContact O-ND2 2.89Å; Y447-N450 PolarHBondContact O-N 3.25Å; V448-N450 VanDerWaalsContact C-N 3.25Å; V448-N450 PolarHBondContact O-N 2.86Å
451N98Very high97.8Very high67 Ų6756.5 Ų56.536%0.35831%0.305SS..Hα-helixtrans-108.7-14.9-175.5-71.6-84000113.9V423 N427 Y447 V448V423-N451 HydrophobicContact CG1-CB 3.9Å; V423-N451 HydrophobicContact CG2-CB 4.31Å; N427-N451 PolarHBondContact ND2-O 3.31Å; Y447-N451 WeakPolarHBondContact O-CB 3.43Å; Y447-N451 PolarHBondContact O-N 3.26Å; Y447-N451 VanDerWaalsContact O-N 3.17Å; Y447-N451 PolarHBondContact O-ND2 2.95Å; V448-N451 PolarHBondContact O-N 3.15Å; V448-N451 VanDerWaalsContact O-N 3.08Å
452I97.8Very high97.8Very high10 Ų1054.1 Ų54.15%0.05129%0.292CS..SBendtrans-80.1128.1170.6-62.6-56.5000110.2P280 I282 V423 A426 A435 V448 A454P280-I452 HydrophobicContact CG-CG2 4.24Å; I282-I452 HydrophobicContact CD1-CD1 4.31Å; I282-I452 HydrophobicContact CD1-CG1 4.31Å; V423-I452 HydrophobicContact CG1-CD1 4.48Å; V423-I452 HydrophobicContact CG2-CD1 4.39Å; A426-I452 HydrophobicContact CB-CD1 3.42Å; A426-I452 VanDerWaalsContact CB-CD1 3.42Å; A435-I452 HydrophobicContact CB-CG2 3.77Å; V448-I452 HydrophobicContact CG1-CG1 3.64Å; V448-I452 WeakPolarHBondContact O-CG1 2.99Å; V448-I452 PolarHBondContact O-N 3.01Å; I452-A454 VanDerWaalsContact C-N 3.29Å; I452-A454 HydrophobicContact CG2-CB 3.98Å; I452-A454 PolarHBondContact O-N 3.42Å
453Q98.2Very high97.6Very high94 Ų9450 Ų5044%0.43927%0.27SS..  trans-84.769.5-179.8-63.3176.6-9.200110.5N427 G432 Y474N427-Q453 PolarHBondContact OD1-N 3.49Å; G432-Q453 VanDerWaalsContact CA-O 3.26Å; G432-Q453 WeakPolarHBondContact CA-O 3.18Å; Q453-Y474 HydrophobicContact CB-CD2 4.25Å
454A98.5Very high97.5Very high9 Ų948.5 Ų48.57%0.07427%0.266CS..  trans-126.8151.8177.200000111.9G432 A435 I452 T456 V457 Y474G432-A454 WeakPolarHBondContact O-CA 3.24Å; A435-A454 HydrophobicContact CB-CB 4Å; I452-A454 VanDerWaalsContact C-N 3.29Å; I452-A454 HydrophobicContact CG2-CB 3.98Å; I452-A454 PolarHBondContact O-N 3.42Å; A454-T456 VanDerWaalsContact C-N 3.35Å; A454-V457 HydrophobicContact CB-CG2 4.36Å; A454-Y474 WeakPolarHBondContact O-CE1 3.44Å
455G98Very high97.3Very high24 Ų2448.1 Ų48.125%0.24726%0.264CS..SBendtrans-65.6-33.9175.700000115.1G432 L433 G472G432-G455 PolarHBondContact O-N 3.1Å; L433-G455 VanDerWaalsContact O-CA 3.28Å; L433-G455 WeakPolarHBondContact O-CA 3.33Å; L433-G455 PolarHBondContact O-N 3.24Å; G455-G472 WeakPolarHBondContact CA-O 3.35Å
456T98.4Very high97.3Very high31 Ų3151.6 Ų51.619%0.1928%0.282CS..EExtended strand (participates in β ladder)trans-137.4133.7178.1-56.20000109.1L433 A434 A435 A454 W458L433-T456 PolarHBondContact O-N 2.76Å; A434-T456 CarbonylContact C-O 3.54Å; A434-T456 WeakPolarHBondContact CA-O 3.44Å; A435-T456 PolarHBondContact N-O 3.12Å; A454-T456 VanDerWaalsContact C-N 3.35Å; T456-W458 HydrophobicContact CG2-CD2 4.25Å; T456-W458 HydrophobicContact CG2-CZ2 3.96Å
457V98.5Very high97.2Very high39 Ų3947.9 Ų47.924%0.23627%0.265CS..EExtended strand (participates in β ladder)trans-123118.5172.3-172.90000108.7A435 V437 A449 A454A435-V457 HydrophobicContact CB-CG1 4.33Å; A435-V457 HydrophobicContact CB-CG2 4.28Å; A435-V457 WeakPolarHBondContact O-CA 3.49Å; V437-V457 HydrophobicContact CG1-CG1 4.37Å; A449-V457 HydrophobicContact CB-CB 4.28Å; A449-V457 HydrophobicContact CB-CG1 4.01Å; A454-V457 HydrophobicContact CB-CG2 4.36Å
458W98.2Very high97.2Very high16 Ų1647 Ų476%0.06127%0.27CS..EExtended strand (participates in β ladder)trans-92.2136174.4-59.9-69.7000110.7T309 A434 A435 G436 V437 T456 C461 Y462 V464 F465T309-W458 HydrophobicContact CG2-CH2 3.98Å; A434-W458 HydrophobicContact CB-CE3 4.43Å; A434-W458 HydrophobicContact CB-CH2 3.68Å; A434-W458 HydrophobicContact CB-CZ3 3.56Å; A435-W458 PolarHBondContact O-N 2.89Å; G436-W458 CarbonylContact C-O 3.57Å; G436-W458 WeakPolarHBondContact CA-O 3.37Å; V437-W458 PolarHBondContact N-O 3.1Å; T456-W458 HydrophobicContact CG2-CD2 4.25Å; T456-W458 HydrophobicContact CG2-CZ2 3.96Å; W458-C461 WeakPolarHBondContact CB-O 3.45Å; W458-Y462 HydrophobicContact CE3-CD1 4.04Å; W458-Y462 HydrophobicContact CE3-CD2 4Å; W458-Y462 HydrophobicContact CE3-CE1 4.08Å; W458-Y462 HydrophobicContact CE3-CE2 4.05Å; W458-Y462 AromaticContact CE3-CG 3.99Å; W458-Y462 HydrophobicContact CE3-CG 3.99Å; W458-Y462 AromaticContact CZ3-CD1 3.87Å; W458-Y462 HydrophobicContact CZ3-CD1 3.87Å; W458-Y462 HydrophobicContact CZ3-CD2 4.5Å; W458-Y462 AromaticContact CZ3-CE1 3.61Å; W458-Y462 HydrophobicContact CZ3-CE1 3.61Å; W458-Y462 HydrophobicContact CZ3-CE2 4.29Å; W458-Y462 HydrophobicContact CZ3-CG 4.3Å; W458-Y462 AromaticContact CZ3-CZ 3.82Å; W458-V464 PolarHBondContact NE1-O 3.13Å; W458-F465 HydrophobicContact CH2-CZ 4.26Å; W458-F465 HydrophobicContact CZ2-CE2 4.24Å; W458-F465 HydrophobicContact CZ2-CZ 4.11Å
459V97.8Very high97.2Very high61 Ų6149.1 Ų49.137%0.3729%0.288SS..EExtended strand (participates in β ladder)trans-110.6123176.1-179.10000108.4V437 A445 C461V437-V459 HydrophobicContact CG1-CB 4.22Å; V437-V459 HydrophobicContact CG1-CG1 4.32Å; V437-V459 HydrophobicContact CG1-CG2 3.73Å; V437-V459 CarbonylContact O-C 3.58Å; V437-V459 WeakPolarHBondContact O-CA 3.28Å; A445-V459 HydrophobicContact CB-CG1 3.69Å; A445-V459 HydrophobicContact CB-CG2 4.36Å; V459-C461 PolarHBondContact O-N 2.75Å; V459-C461 VanDerWaalsContact O-N 3.13Å; V459-C461 PolarHBondContact O-SG 2.79Å
460N96.8Very high97.2Very high83 Ų8350.5 Ų50.544%0.44430%0.295SS..SBendtrans54.127.5-178.7-63-36.8000114.7V437 F438 T439V437-N460 PolarHBondContact O-N 3.34Å; F438-N460 VanDerWaalsContact CA-OD1 3.29Å; F438-N460 WeakPolarHBondContact CA-OD1 3.37Å; T439-N460 PolarHBondContact N-OD1 3.04Å; T439-N460 PolarHBondContact O-ND2 3.29Å; T439-N460 PolarHBondContact O-OD1 2.66Å; T439-N460 VanDerWaalsContact O-OD1 3.08Å
461C96.3Very high97.3Very high37 Ų3744.7 Ų44.725%0.2526%0.263CS..  trans-159.2173.2173.355.70000109F438 W458 V459 V464F438-C461 WeakPolarHBondContact CZ-O 3.39Å; W458-C461 WeakPolarHBondContact CB-O 3.45Å; V459-C461 PolarHBondContact O-N 2.75Å; V459-C461 VanDerWaalsContact O-N 3.13Å; V459-C461 PolarHBondContact O-SG 2.79Å; C461-V464 HydrophobicContact CB-CG2 3.95Å
462Y97.2Very high97.3Very high11 Ų1141.5 Ų41.54%0.04325%0.246CC..SBendtrans-149.4149.6175.9-148.9-86.1000111S279 N281 G299 T309 G311 F438 W458 V464S279-Y462 WeakPolarHBondContact CB-OH 3.32Å; N281-Y462 HydrophobicContact CB-CE2 3.84Å; G299-Y462 VanDerWaalsContact CA-CD1 3.42Å; T309-Y462 VanDerWaalsContact O-CE1 3.31Å; T309-Y462 WeakPolarHBondContact O-CE1 3.46Å; T309-Y462 PolarHBondContact O-OH 3.24Å; G311-Y462 WeakPolarHBondContact CA-OH 3.4Å; G311-Y462 PolarHBondContact N-OH 2.74Å; F438-Y462 HydrophobicContact CE2-CD2 4.41Å; W458-Y462 HydrophobicContact CE3-CD1 4.04Å; W458-Y462 HydrophobicContact CE3-CD2 4Å; W458-Y462 HydrophobicContact CE3-CE1 4.08Å; W458-Y462 HydrophobicContact CE3-CE2 4.05Å; W458-Y462 AromaticContact CE3-CG 3.99Å; W458-Y462 HydrophobicContact CE3-CG 3.99Å; W458-Y462 AromaticContact CZ3-CD1 3.87Å; W458-Y462 HydrophobicContact CZ3-CD1 3.87Å; W458-Y462 HydrophobicContact CZ3-CD2 4.5Å; W458-Y462 AromaticContact CZ3-CE1 3.61Å; W458-Y462 HydrophobicContact CZ3-CE1 3.61Å; W458-Y462 HydrophobicContact CZ3-CE2 4.29Å; W458-Y462 HydrophobicContact CZ3-CG 4.3Å; W458-Y462 AromaticContact CZ3-CZ 3.82Å; Y462-V464 PolarHBondContact O-N 2.89Å
463N94.1Very high97.3Very high31 Ų3141.2 Ų41.217%0.16625%0.245CC..SBendtrans5532.5179.1-73.2-22.2000114.7G299 T309 F465G299-N463 PolarHBondContact O-ND2 3.44Å; T309-N463 PolarHBondContact OG1-OD1 2.77Å; N463-F465 HydrophobicContact CB-CE2 4.15Å; N463-F465 VanDerWaalsContact O-CD2 3.27Å; N463-F465 WeakPolarHBondContact O-CD2 3.34Å
464V95.1Very high97.3Very high91 Ų9142.2 Ų42.255%0.55225%0.246SC*.  trans-87.4111.6173.3-178.40000108.9W458 C461 Y462W458-V464 PolarHBondContact NE1-O 3.13Å; C461-V464 HydrophobicContact CB-CG2 3.95Å; Y462-V464 PolarHBondContact O-N 2.89Å
465F94.8Very high97.2Very high47 Ų4745.7 Ų45.721%0.20626%0.259CS..  trans-111142.8178.3-66.1-93000110.8W156 T309 W458 N463 F471W156-F465 AromaticContact CH2-CD1 3.62Å; W156-F465 HydrophobicContact CH2-CD1 3.62Å; W156-F465 AromaticContact CH2-CE1 3.8Å; W156-F465 HydrophobicContact CH2-CE1 3.8Å; W156-F465 HydrophobicContact CH2-CG 4.47Å; W156-F465 HydrophobicContact CZ2-CD1 4.05Å; T309-F465 HydrophobicContact CG2-CZ 3.98Å; W458-F465 HydrophobicContact CH2-CZ 4.26Å; W458-F465 HydrophobicContact CZ2-CE2 4.24Å; W458-F465 HydrophobicContact CZ2-CZ 4.11Å; N463-F465 HydrophobicContact CB-CE2 4.15Å; N463-F465 VanDerWaalsContact O-CD2 3.27Å; N463-F465 WeakPolarHBondContact O-CD2 3.34Å; F465-F471 HydrophobicContact CD1-CD2 4.09Å; F465-F471 HydrophobicContact CD1-CE2 4.41Å; F465-F471 AromaticContact CE1-CD2 3.5Å; F465-F471 HydrophobicContact CE1-CD2 3.5Å; F465-F471 VanDerWaalsContact CE1-CD2 3.5Å; F465-F471 HydrophobicContact CE1-CE1 4.47Å; F465-F471 AromaticContact CE1-CE2 3.41Å; F465-F471 HydrophobicContact CE1-CE2 3.41Å; F465-F471 VanDerWaalsContact CE1-CE2 3.41Å; F465-F471 HydrophobicContact CE1-CG 4.09Å; F465-F471 AromaticContact CE1-CZ 3.91Å; F465-F471 HydrophobicContact CE1-CZ 3.91Å; F465-F471 HydrophobicContact CZ-CE2 4.04Å; F465-F471 HydrophobicContact CZ-CZ 4.4Å
466D96Very high97.3Very high77 Ų7747.7 Ų47.741%0.41226%0.263SS..  trans-140.8137.8172.4-170.1-76.7000109.3T468 A469D466-T468 PolarHBondContact O-N 3.21Å; D466-T468 VanDerWaalsContact O-N 3.09Å; D466-T468 WeakPolarHBondContact OD1-CB 3.43Å; D466-T468 WeakPolarHBondContact OD1-CG2 3.36Å; D466-T468 PolarHBondContact OD1-N 3Å; D466-T468 PolarHBondContact OD1-OG1 3.39Å; D466-A469 PolarHBondContact O-N 2.95Å
467A97.4Very high97.3Very high14 Ų1446.2 Ų46.212%0.11625%0.254CS..THydrogen-bonded Turntrans-61.7-20.1-177.800000113.1Y110 G484Y110-A467 HydrophobicContact CD1-CB 3.95Å; Y110-A467 WeakPolarHBondContact CD1-O 3.18Å; Y110-A467 HydrophobicContact CD2-CB 4.46Å; Y110-A467 WeakPolarHBondContact CE1-O 3.26Å; Y110-A467 HydrophobicContact CG-CB 3.78Å; A467-G484 WeakPolarHBondContact O-CA 3.33Å; A467-G484 PolarHBondContact O-N 2.63Å
468T97.4Very high97.3Very high86 Ų8644.7 Ų44.753%0.52825%0.246SC..THydrogen-bonded Turntrans-78.4-23.4177.367.40000113.5Y110 D466 G484Y110-T468 HydrophobicContact CD2-CG2 3.93Å; Y110-T468 HydrophobicContact CE2-CG2 3.6Å; D466-T468 PolarHBondContact O-N 3.21Å; D466-T468 VanDerWaalsContact O-N 3.09Å; D466-T468 WeakPolarHBondContact OD1-CB 3.43Å; D466-T468 WeakPolarHBondContact OD1-CG2 3.36Å; D466-T468 PolarHBondContact OD1-N 3Å; D466-T468 PolarHBondContact OD1-OG1 3.39Å; T468-G484 VanDerWaalsContact O-CA 3.25Å; T468-G484 WeakPolarHBondContact O-CA 3.4Å
469A97.8Very high97.2Very high47 Ų4748 Ų4839%0.38826%0.261SS..SBendtrans-93.4134.1-178.400000110.6D466 L483D466-A469 PolarHBondContact O-N 2.95Å; A469-L483 WeakPolarHBondContact O-CB 3.45Å
470P98.1Very high97Very high56 Ų5646.4 Ų46.436%0.36426%0.257SS..  trans-68.4141.317530.8-34.5000110.4R481 E482 Y486P470-R481 HydrophobicContact CB-CB 4.24Å; P470-R481 HydrophobicContact CB-CG 4.35Å; P470-E482 CarbonylContact C-O 3.52Å; P470-E482 WeakPolarHBondContact CA-O 3.36Å; P470-Y486 HydrophobicContact CG-CD2 4.34Å
471F98.6Very high97.1Very high8 Ų845.5 Ų45.54%0.03525%0.248CC..BIsolated β-bridgetrans-122.3137.6175.7-178.3-98.4000110W156 T309 L433 F465 R481 E482 L483W156-F471 HydrophobicContact CH2-CD1 4.13Å; W156-F471 HydrophobicContact CH2-CG 4.28Å; W156-F471 HydrophobicContact CZ3-CB 4.3Å; W156-F471 AromaticContact CZ3-CD1 3.55Å; W156-F471 HydrophobicContact CZ3-CD1 3.55Å; W156-F471 HydrophobicContact CZ3-CE1 4.12Å; W156-F471 HydrophobicContact CZ3-CG 4.05Å; T309-F471 HydrophobicContact CG2-CE2 3.61Å; T309-F471 HydrophobicContact CG2-CZ 3.43Å; T309-F471 VanDerWaalsContact CG2-CZ 3.43Å; L433-F471 HydrophobicContact CD1-CE1 4Å; L433-F471 HydrophobicContact CD1-CE2 4.5Å; L433-F471 HydrophobicContact CD1-CZ 3.77Å; L433-F471 HydrophobicContact CD2-CZ 3.96Å; L433-F471 HydrophobicContact CG-CZ 3.84Å; F465-F471 HydrophobicContact CD1-CD2 4.09Å; F465-F471 HydrophobicContact CD1-CE2 4.41Å; F465-F471 AromaticContact CE1-CD2 3.5Å; F465-F471 HydrophobicContact CE1-CD2 3.5Å; F465-F471 VanDerWaalsContact CE1-CD2 3.5Å; F465-F471 HydrophobicContact CE1-CE1 4.47Å; F465-F471 AromaticContact CE1-CE2 3.41Å; F465-F471 HydrophobicContact CE1-CE2 3.41Å; F465-F471 VanDerWaalsContact CE1-CE2 3.41Å; F465-F471 HydrophobicContact CE1-CG 4.09Å; F465-F471 AromaticContact CE1-CZ 3.91Å; F465-F471 HydrophobicContact CE1-CZ 3.91Å; F465-F471 HydrophobicContact CZ-CE2 4.04Å; F465-F471 HydrophobicContact CZ-CZ 4.4Å; F471-R481 CarbonylContact O-C 3.22Å; F471-R481 VanDerWaalsContact O-CA 3.32Å; F471-R481 WeakPolarHBondContact O-CA 3.46Å; F471-R481 WeakPolarHBondContact O-CD 3.17Å; F471-E482 PolarHBondContact N-O 2.74Å; F471-E482 PolarHBondContact O-N 3.2Å; F471-L483 HydrophobicContact CB-CD1 4.29Å
472G97.8Very high97.2Very high0 Ų044 Ų440%024%0.237CC..  trans155.8163.316900000115.9E274 G455 R481E274-G472 VanDerWaalsContact CD-CA 3.43Å; E274-G472 WeakPolarHBondContact OE1-CA 2.83Å; E274-G472 WeakPolarHBondContact OE2-CA 3.19Å; G455-G472 WeakPolarHBondContact CA-O 3.35Å; G472-R481 VanDerWaalsContact O-CZ 3.26Å; G472-R481 PolarHBondContact O-NH1 3.37Å
473G97.5Very high97.2Very high3 Ų343.6 Ų43.63%0.03124%0.235CC..  trans-79.2159.8-164.700000117.9R481G473-R481 PolarHBondContact O-NH1 2.7Å; G473-R481 PolarHBondContact O-NH2 3.05Å
474Y97.9Very high97.4Very high115 Ų11542.1 Ų42.145%0.45123%0.228SC..SBendtrans-94.3165.6155.8-80.448.6000109.2G432 Q453 A454 M476 S477G432-Y474 WeakPolarHBondContact O-CB 3.34Å; G432-Y474 PolarHBondContact O-N 3.44Å; Q453-Y474 HydrophobicContact CB-CD2 4.25Å; A454-Y474 WeakPolarHBondContact O-CE1 3.44Å; Y474-M476 PolarHBondContact O-N 2.64Å; Y474-S477 WeakPolarHBondContact O-CB 3.41Å; Y474-S477 PolarHBondContact O-N 3.36Å; Y474-S477 VanDerWaalsContact O-N 3.08Å
475K98.2Very high97.5Very high82 Ų8243.2 Ų43.236%0.35723%0.227SC..G310 helixtrans52.7-129.8173.8-52.7177.8-172.2164.90112.2N427 T429 I430 Y431 S477N427-K475 PolarHBondContact O-NZ 3.36Å; T429-K475 PolarHBondContact O-NZ 3.01Å; I430-K475 WeakPolarHBondContact O-CB 3.32Å; Y431-K475 WeakPolarHBondContact O-CD 3.29Å; Y431-K475 PolarHBondContact O-NZ 3.18Å; K475-S477 VanDerWaalsContact C-N 3.29Å; K475-S477 PolarHBondContact O-N 3.48Å
476M98.3Very high97.6Very high66 Ų6648.3 Ų48.333%0.32525%0.246SC..G310 helixtrans-85.94.8-179-54.9-166.170.300113.9T253 L275 I430 Y474 G478T253-M476 HydrophobicContact CG2-CB 4.06Å; T253-M476 HydrophobicContact CG2-CE 3.91Å; T253-M476 PolarHBondContact OG1-O 3.47Å; L275-M476 WeakPolarHBondContact CD1-O 3.34Å; I430-M476 HydrophobicContact CB-CB 4.47Å; I430-M476 HydrophobicContact CB-CG 4.25Å; I430-M476 HydrophobicContact CB-SD 3.92Å; I430-M476 HydrophobicContact CD1-SD 3.99Å; I430-M476 HydrophobicContact CG1-SD 4.43Å; I430-M476 HydrophobicContact CG2-SD 4.39Å; I430-M476 WeakPolarHBondContact O-CB 3.47Å; I430-M476 PolarHBondContact O-N 2.94Å; Y474-M476 PolarHBondContact O-N 2.64Å; M476-G478 PolarHBondContact O-N 2.86Å
477S98.7Very high97.7Very high0 Ų044.7 Ų44.70%023%0.226CC..G310 helixtrans-79.7-1.7171-70.10000113.1L275 G276 Y431 G432 L433 Y474 K475L275-S477 PolarHBondContact N-O 2.97Å; G276-S477 WeakPolarHBondContact O-CB 3.46Å; G276-S477 PolarHBondContact O-OG 3.44Å; Y431-S477 WeakPolarHBondContact CA-OG 3.1Å; Y431-S477 WeakPolarHBondContact CB-OG 3.16Å; G432-S477 PolarHBondContact N-OG 2.98Å; L433-S477 PolarHBondContact N-OG 2.8Å; Y474-S477 WeakPolarHBondContact O-CB 3.41Å; Y474-S477 PolarHBondContact O-N 3.36Å; Y474-S477 VanDerWaalsContact O-N 3.08Å; K475-S477 VanDerWaalsContact C-N 3.29Å; K475-S477 PolarHBondContact O-N 3.48Å
478G98.1Very high97.8Very high7 Ų744.2 Ų44.27%0.07222%0.222CC..EExtended strand (participates in β ladder)trans131.2-177.5171.800000114.3L273 M476L273-G478 CarbonylContact O-C 3.41Å; L273-G478 WeakPolarHBondContact O-CA 3.29Å; M476-G478 PolarHBondContact O-N 2.86Å
479F96.5Very high97.7Very high86 Ų8643.7 Ų43.738%0.37722%0.216SC..EExtended strand (participates in β ladder)trans-152.4155.7174.362.6-97.2000110.7M260 L271 S272 L273M260-F479 HydrophobicContact SD-CE1 4.09Å; M260-F479 HydrophobicContact SD-CZ 4.45Å; L271-F479 HydrophobicContact CB-CE2 4.04Å; L271-F479 HydrophobicContact CB-CZ 4.06Å; L271-F479 HydrophobicContact CD2-CZ 3.84Å; L271-F479 HydrophobicContact CG-CE2 4.17Å; L271-F479 HydrophobicContact CG-CZ 3.84Å; L271-F479 VanDerWaalsContact O-CE2 3.28Å; L271-F479 WeakPolarHBondContact O-CE2 3.36Å; S272-F479 WeakPolarHBondContact CA-O 3.04Å; L273-F479 HydrophobicContact CB-CE1 4.46Å; L273-F479 HydrophobicContact CD1-CD1 4.14Å; L273-F479 HydrophobicContact CD1-CE1 3.45Å; L273-F479 VanDerWaalsContact CD1-CE1 3.45Å; L273-F479 HydrophobicContact CD1-CZ 3.98Å; L273-F479 HydrophobicContact CG-CD1 4.47Å; L273-F479 HydrophobicContact CG-CE1 3.94Å; L273-F479 HydrophobicContact CG-CZ 4.12Å; L273-F479 PolarHBondContact N-O 3.36Å; L273-F479 PolarHBondContact O-N 3.16Å; L273-F479 VanDerWaalsContact O-N 3.07Å
480G94.8Very high97.7Very high28 Ų2842.5 Ų42.529%0.28921%0.205SC..SBendtrans85.2179-15800000110.6
481R98Very high97.7Very high63 Ų6340 Ų4024%0.23819%0.188CC..  trans-137148.5171.6-65.4-65.6178.4-101.99.3108.6P470 F471 G472 G473 G487 S490P470-R481 HydrophobicContact CB-CB 4.24Å; P470-R481 HydrophobicContact CB-CG 4.35Å; F471-R481 CarbonylContact O-C 3.22Å; F471-R481 VanDerWaalsContact O-CA 3.32Å; F471-R481 WeakPolarHBondContact O-CA 3.46Å; F471-R481 WeakPolarHBondContact O-CD 3.17Å; G472-R481 VanDerWaalsContact O-CZ 3.26Å; G472-R481 PolarHBondContact O-NH1 3.37Å; G473-R481 PolarHBondContact O-NH1 2.7Å; G473-R481 PolarHBondContact O-NH2 3.05Å; R481-G487 WeakPolarHBondContact O-CA 3.38Å; R481-S490 PolarHBondContact O-OG 2.67Å
482E98Very high97.7Very high6 Ų639.7 Ų39.73%0.02819%0.187CC..BIsolated β-bridgetrans-102.8166.4163.7-58.2-165.5148.500108.9W156 K157 E274 P470 F471W156-E482 HydrophobicContact CE3-CB 4.19Å; K157-E482 IonicContact NZ-OE1 2.79Å; K157-E482 PolarHBondContact NZ-OE1 2.72Å; K157-E482 IonicContact NZ-OE2 3.49Å; E274-E482 HydrophobicContact CG-CG 3.88Å; P470-E482 CarbonylContact C-O 3.52Å; P470-E482 WeakPolarHBondContact CA-O 3.36Å; F471-E482 PolarHBondContact N-O 2.74Å; F471-E482 PolarHBondContact O-N 3.2Å
483L98.2Very high97.7Very high2 Ų243.8 Ų43.81%0.0121%0.206CC..SBendtrans60.3175.6-177.4-53.8-174.8000114.3Y111 W156 A469 F471 G487Y111-L483 HydrophobicContact CE2-CD2 4.36Å; Y111-L483 WeakPolarHBondContact OH-CA 3.47Å; Y111-L483 PolarHBondContact OH-N 3.45Å; Y111-L483 VanDerWaalsContact OH-N 3.14Å; Y111-L483 PolarHBondContact OH-O 2.64Å; W156-L483 HydrophobicContact CD2-CD1 4.13Å; W156-L483 HydrophobicContact CD2-CD2 3.77Å; W156-L483 HydrophobicContact CD2-CG 3.96Å; W156-L483 HydrophobicContact CE3-CD1 4.31Å; W156-L483 HydrophobicContact CE3-CD2 4.4Å; W156-L483 HydrophobicContact CE3-CG 4.12Å; W156-L483 HydrophobicContact CG-CD2 3.8Å; W156-L483 HydrophobicContact CG-CG 4.48Å; W156-L483 HydrophobicContact CH2-CD1 3.79Å; W156-L483 HydrophobicContact CH2-CG 4.47Å; W156-L483 HydrophobicContact CZ2-CD1 3.57Å; W156-L483 HydrophobicContact CZ2-CG 4.32Å; W156-L483 HydrophobicContact CZ3-CD1 4.16Å; W156-L483 HydrophobicContact CZ3-CG 4.38Å; A469-L483 WeakPolarHBondContact O-CB 3.45Å; F471-L483 HydrophobicContact CB-CD1 4.29Å; L483-G487 VanDerWaalsContact O-CA 3.25Å; L483-G487 WeakPolarHBondContact O-CA 3.22Å; L483-G487 PolarHBondContact O-N 2.88Å
484G98Very high97.7Very high0 Ų047 Ų470%023%0.225CC..THydrogen-bonded Turntrans58.4-173.2178.900000114.4Y110 Y111 A467 T468 Y486Y110-G484 VanDerWaalsContact OH-C 3.31Å; Y110-G484 WeakPolarHBondContact OH-CA 3.27Å; Y111-G484 PolarHBondContact OH-O 2.82Å; A467-G484 WeakPolarHBondContact O-CA 3.33Å; A467-G484 PolarHBondContact O-N 2.63Å; T468-G484 VanDerWaalsContact O-CA 3.25Å; T468-G484 WeakPolarHBondContact O-CA 3.4Å; G484-Y486 VanDerWaalsContact C-N 3.34Å
485Q97.8Very high97.7Very high115 Ų11546 Ų4654%0.53722%0.223SC..THydrogen-bonded Turntrans-66.5-38.6173.3-177.11805.200111.4Y110 W114 G487 L488Y110-Q485 PolarHBondContact OH-N 2.81Å; W114-Q485 HydrophobicContact CH2-CB 3.93Å; W114-Q485 HydrophobicContact CH2-CG 3.6Å; W114-Q485 HydrophobicContact CZ2-CB 3.81Å; W114-Q485 HydrophobicContact CZ2-CG 4.02Å; W114-Q485 HydrophobicContact CZ3-CG 4.12Å; Q485-G487 VanDerWaalsContact C-N 3.25Å; Q485-G487 PolarHBondContact O-N 2.77Å; Q485-L488 WeakPolarHBondContact O-CB 3.14Å; Q485-L488 PolarHBondContact O-N 3.49Å; Q485-L488 VanDerWaalsContact O-N 3.11Å
486Y97.3Very high97.6Very high153 Ų15345.5 Ų45.560%0.623%0.23SC*.G310 helixtrans-62.7-29.6-179-74.6-89.6000112.7P470 G484 L488 D489P470-Y486 HydrophobicContact CG-CD2 4.34Å; G484-Y486 VanDerWaalsContact C-N 3.34Å; Y486-L488 PolarHBondContact O-N 3.48Å; Y486-D489 VanDerWaalsContact O-CB 3.3Å; Y486-D489 WeakPolarHBondContact O-CB 3.11Å; Y486-D489 PolarHBondContact O-N 2.86Å; Y486-D489 VanDerWaalsContact O-N 3.14Å
487G97.8Very high97.6Very high1 Ų144.5 Ų44.51%0.0123%0.227CC..G310 helixtrans-63.8-25.1175.500000114.1R481 L483 Q485 D489 S490R481-G487 WeakPolarHBondContact O-CA 3.38Å; L483-G487 VanDerWaalsContact O-CA 3.25Å; L483-G487 WeakPolarHBondContact O-CA 3.22Å; L483-G487 PolarHBondContact O-N 2.88Å; Q485-G487 VanDerWaalsContact C-N 3.25Å; Q485-G487 PolarHBondContact O-N 2.77Å; G487-D489 VanDerWaalsContact C-N 3.26Å; G487-D489 PolarHBondContact O-N 2.85Å; G487-S490 WeakPolarHBondContact O-CB 3.45Å; G487-S490 PolarHBondContact O-N 2.85Å
488L98.1Very high97.3Very high5 Ų548.1 Ų48.13%0.02625%0.253CS..G310 helixtrans-67.4-27.3175.6-61.5168.3000112.2Y111 W114 I118 P160 Q485 Y486 S490 Y491 T492Y111-L488 HydrophobicContact CD1-CD2 3.7Å; Y111-L488 HydrophobicContact CD1-CG 4.46Å; Y111-L488 HydrophobicContact CE1-CD2 3.61Å; Y111-L488 HydrophobicContact CE1-CG 3.99Å; W114-L488 HydrophobicContact CB-CD1 4.04Å; W114-L488 HydrophobicContact CB-CD2 4.44Å; W114-L488 HydrophobicContact CD2-CD1 3.58Å; W114-L488 HydrophobicContact CE3-CD1 3.58Å; W114-L488 HydrophobicContact CG-CD1 3.8Å; W114-L488 HydrophobicContact CZ3-CD1 4.27Å; I118-L488 HydrophobicContact CD1-CD2 4.33Å; I118-L488 HydrophobicContact CG1-CD1 4.2Å; P160-L488 HydrophobicContact CB-CD2 4.19Å; Q485-L488 WeakPolarHBondContact O-CB 3.14Å; Q485-L488 PolarHBondContact O-N 3.49Å; Q485-L488 VanDerWaalsContact O-N 3.11Å; Y486-L488 PolarHBondContact O-N 3.48Å; L488-S490 PolarHBondContact O-N 3.03Å; L488-Y491 CarbonylContact O-C 3.44Å; L488-Y491 PolarHBondContact O-N 2.93Å; L488-T492 PolarHBondContact O-N 2.88Å; L488-T492 PolarHBondContact O-OG1 3.4Å
489D96.7Very high96.8Very high74 Ų7454.2 Ų54.240%0.39627%0.274SS..G310 helixtrans-59.1-40.3179-67.4-9.6000110.7R135 Y486 G487 Y491 T492R135-D489 IonicContact CZ-OD1 3.99Å; R135-D489 IonicContact NH1-OD1 3.77Å; R135-D489 IonicContact NH2-OD1 2.59Å; R135-D489 PolarHBondContact NH2-OD1 3.45Å; Y486-D489 VanDerWaalsContact O-CB 3.3Å; Y486-D489 WeakPolarHBondContact O-CB 3.11Å; Y486-D489 PolarHBondContact O-N 2.86Å; Y486-D489 VanDerWaalsContact O-N 3.14Å; G487-D489 VanDerWaalsContact C-N 3.26Å; G487-D489 PolarHBondContact O-N 2.85Å; D489-Y491 PolarHBondContact O-N 2.94Å; D489-Y491 VanDerWaalsContact O-N 3.12Å; D489-T492 PolarHBondContact O-N 2.89Å
490S96.8Very high96.3Very high22 Ų2252.3 Ų52.315%0.15427%0.267CS..G310 helixtrans-60.7-22176.9-63.10000112.9K246 R481 G487 L488K246-S490 WeakPolarHBondContact CD-O 3.06Å; K246-S490 WeakPolarHBondContact CE-O 3.38Å; R481-S490 PolarHBondContact O-OG 2.67Å; G487-S490 WeakPolarHBondContact O-CB 3.45Å; G487-S490 PolarHBondContact O-N 2.85Å; L488-S490 PolarHBondContact O-N 3.03Å
491Y98.6Very high95.6Very high4 Ų452.3 Ų52.32%0.01626%0.262CS..G310 helixtrans-114.313.7-174-70.3-77.6000113.8V138 C141 K157 P160 A161 C164 N166 K246 A248 L488 D489V138-Y491 WeakPolarHBondContact CG2-O 3.31Å; C141-Y491 HydrophobicContact CB-CE1 4.31Å; K157-Y491 PolarHBondContact O-OH 3.1Å; P160-Y491 HydrophobicContact CB-CD2 3.68Å; P160-Y491 HydrophobicContact CB-CE2 3.99Å; P160-Y491 HydrophobicContact CB-CG 4.43Å; P160-Y491 HydrophobicContact CG-CD2 3.85Å; P160-Y491 HydrophobicContact CG-CE2 3.59Å; A161-Y491 HydrophobicContact CB-CD1 3.62Å; A161-Y491 HydrophobicContact CB-CE1 3.55Å; A161-Y491 HydrophobicContact CB-CG 4.35Å; C164-Y491 WeakPolarHBondContact CB-O 3.16Å; N166-Y491 PolarHBondContact ND2-O 3.29Å; K246-Y491 HydrophobicContact CD-CD1 4.04Å; K246-Y491 HydrophobicContact CD-CE1 4.08Å; A248-Y491 WeakPolarHBondContact CB-OH 3.3Å; L488-Y491 CarbonylContact O-C 3.44Å; L488-Y491 PolarHBondContact O-N 2.93Å; D489-Y491 PolarHBondContact O-N 2.94Å; D489-Y491 VanDerWaalsContact O-N 3.12Å
492T98.3Very high94.2Very high2 Ų255.4 Ų55.41%0.01229%0.288CS..EExtended strand (participates in β ladder)trans-131.1145.1176.855.80000113.3I118 R135 E136 C164 R270 L488 D489I118-T492 HydrophobicContact CG2-CG2 3.97Å; R135-T492 HydrophobicContact CB-CG2 4.33Å; R135-T492 PolarHBondContact NE-OG1 2.82Å; R135-T492 VanDerWaalsContact NE-OG1 3.14Å; R135-T492 PolarHBondContact NH1-OG1 2.83Å; R135-T492 PolarHBondContact NH2-OG1 3.46Å; E136-T492 CarbonylContact O-C 3.47Å; E136-T492 WeakPolarHBondContact O-CA 3.16Å; C164-T492 HydrophobicContact CB-CG2 4.04Å; C164-T492 VanDerWaalsContact SG-CG2 3.56Å; R270-T492 PolarHBondContact NH1-O 2.84Å; R270-T492 PolarHBondContact NH2-O 3.13Å; L488-T492 PolarHBondContact O-N 2.88Å; L488-T492 PolarHBondContact O-OG1 3.4Å; D489-T492 PolarHBondContact O-N 2.89Å
493E97.6Very high92.8Very high85 Ų8559 Ų5940%0.39733%0.326SS..EExtended strand (participates in β ladder)trans-104.7131.1172.1-174.763.7-90.500109.9E136 R270E136-E493 PolarHBondContact N-O 3.46Å; E136-E493 PolarHBondContact O-N 2.82Å; R270-E493 IonicContact CZ-OE1 3.66Å; R270-E493 IonicContact CZ-OE2 2.86Å; R270-E493 IonicContact NE-OE2 3.03Å; R270-E493 PolarHBondContact NE-OE2 2.88Å; R270-E493 IonicContact NH1-OE2 2.7Å; R270-E493 IonicContact NH2-OE1 3.71Å; R270-E493 PolarHBondContact NH2-OE1 3.41Å; R270-E493 IonicContact NH2-OE2 3.59Å; R270-E493 PolarHBondContact NH2-OE2 3.49Å
494V98Very high91.1Very high71 Ų7162 Ų6243%0.4334%0.34SS..EExtended strand (participates in β ladder)trans-92.4112.1-177.8-176.50000108.8T133 R134T133-V494 HydrophobicContact CG2-CG1 4.15Å; R134-V494 WeakPolarHBondContact O-CA 3.46Å
495K97.8Very high89.5Confident94 Ų9465.7 Ų65.741%0.40936%0.36SS..EExtended strand (participates in β ladder)trans-101.5120172.5-177.4178.6-67.4163.50109.8T133 R134 E136 V497T133-K495 CarbonylContact C-O 3.4Å; T133-K495 WeakPolarHBondContact CA-O 3.33Å; R134-K495 HydrophobicContact CB-CB 4.43Å; R134-K495 PolarHBondContact N-O 2.95Å; R134-K495 PolarHBondContact O-N 2.87Å; E136-K495 IonicContact OE1-NZ 2.67Å; E136-K495 PolarHBondContact OE1-NZ 3.08Å; E136-K495 VanDerWaalsContact OE2-CE 3.3Å; E136-K495 WeakPolarHBondContact OE2-CE 3.34Å; E136-K495 IonicContact OE2-NZ 3.51Å; E136-K495 PolarHBondContact OE2-NZ 3.26Å; K495-V497 HydrophobicContact CD-CG2 4.33Å; K495-V497 HydrophobicContact CG-CG2 4.16Å
496S97.3Very high88Confident72 Ų7265 Ų6550%0.50336%0.359SS..EExtended strand (participates in β ladder)trans-88.5133.9169.4-170.70000110.2
497V96.4Very high86.3Confident44 Ų4465.4 Ų65.427%0.26736%0.364SS..EExtended strand (participates in β ladder)trans-127.8120.9177.2-1770000108.3A131 Y132 K495A131-V497 WeakPolarHBondContact CA-O 3.27Å; Y132-V497 HydrophobicContact CD1-CB 4.14Å; Y132-V497 HydrophobicContact CD1-CG1 4.47Å; Y132-V497 HydrophobicContact CE1-CB 3.62Å; Y132-V497 HydrophobicContact CE1-CG1 3.62Å; Y132-V497 HydrophobicContact CE1-CG2 4.47Å; Y132-V497 HydrophobicContact CE2-CB 4.19Å; Y132-V497 HydrophobicContact CE2-CG2 4.28Å; Y132-V497 PolarHBondContact N-O 3.49Å; Y132-V497 PolarHBondContact O-N 3.25Å; K495-V497 HydrophobicContact CD-CG2 4.33Å; K495-V497 HydrophobicContact CG-CG2 4.16Å
498S93.6Very high84.5Confident77 Ų7769.7 Ų69.754%0.53838%0.384SS..EExtended strand (participates in β ladder)trans-117136.7175.5-610000109.6F130F130-S498 WeakPolarHBondContact O-CA 3.45Å
499R88.3Confident82.7Confident134 Ų13469.5 Ų69.551%0.50638%0.383SS..EExtended strand (participates in β ladder)trans-131.2158.3170.868.3172.7-172.5167.80.4110.4Y129 F130 S501Y129-R499 CarbonylContact C-O 3.54Å; Y129-R499 VanDerWaalsContact CA-O 3.27Å; Y129-R499 WeakPolarHBondContact CA-O 3.49Å; F130-R499 HydrophobicContact CB-CG 4.08Å; F130-R499 HydrophobicContact CD1-CG 4.1Å; F130-R499 PolarHBondContact N-O 3.23Å; F130-R499 PolarHBondContact O-N 2.87Å; R499-S501 PolarHBondContact O-N 3.13Å
500I85.7Confident81.2Confident47 Ų4771.4 Ų71.424%0.24139%0.389CS..EExtended strand (participates in β ladder)trans-62.2135.2168-67.5169.2000108.6Y129 E504 I506Y129-I500 HydrophobicContact CD1-CG1 4.19Å; Y129-I500 HydrophobicContact CE1-CG1 3.92Å; I500-E504 HydrophobicContact CG2-CB 3.57Å; I500-E504 WeakPolarHBondContact CG2-O 3.45Å; I500-I506 HydrophobicContact CD1-CB 4.09Å; I500-I506 HydrophobicContact CD1-CD1 4.05Å; I500-I506 HydrophobicContact CD1-CG1 3.59Å; I500-I506 HydrophobicContact CD1-CG2 4.01Å
501S80.2Confident79.5Confident27 Ų2775 Ų7519%0.18941%0.406CS..PPolyproline II helixtrans-60.2142.5179.6-71.20000110.8P127 K128 Y129 F130 R499 G503 E504P127-S501 PolarHBondContact O-OG 2.87Å; K128-S501 VanDerWaalsContact C-OG 3.29Å; K128-S501 WeakPolarHBondContact O-CB 3.49Å; K128-S501 PolarHBondContact O-N 3.38Å; K128-S501 PolarHBondContact O-OG 2.8Å; Y129-S501 WeakPolarHBondContact CA-OG 3.44Å; Y129-S501 PolarHBondContact N-OG 2.99Å; Y129-S501 PolarHBondContact O-OG 2.89Å; F130-S501 PolarHBondContact N-OG 3.5Å; R499-S501 PolarHBondContact O-N 3.13Å; S501-G503 PolarHBondContact O-N 2.91Å; S501-G503 VanDerWaalsContact O-N 3.13Å; S501-E504 PolarHBondContact O-N 3.1Å; S501-E504 VanDerWaalsContact O-N 3.1Å
502V68.5Low77.7Confident128 Ų12881.3 Ų81.378%0.77643%0.43SS*.THydrogen-bonded Turntrans-61.4117.9176.6179.90000108.4
503G67.6Low76Confident81 Ų8185 Ų8584%0.83545%0.447SS*.THydrogen-bonded Turntrans114.5-16.5-176.400000114.7S501S501-G503 PolarHBondContact O-N 2.91Å; S501-G503 VanDerWaalsContact O-N 3.13Å
504E62.9Low74.2Confident65 Ų6586.7 Ų86.730%0.30446%0.455SS..  trans-91.1122.7174.3-71.3-73155.800110.2I500 S501 V509I500-E504 HydrophobicContact CG2-CB 3.57Å; I500-E504 WeakPolarHBondContact CG2-O 3.45Å; S501-E504 PolarHBondContact O-N 3.1Å; S501-E504 VanDerWaalsContact O-N 3.1Å; E504-V509 HydrophobicContact CB-CG2 3.85Å; E504-V509 HydrophobicContact CG-CG2 4.42Å; E504-V509 VanDerWaalsContact OE2-CG2 3.29Å; E504-V509 WeakPolarHBondContact OE2-CG2 3.33Å
505N64.6Low72.4Confident79 Ų7990.2 Ų90.242%0.42247%0.465SS..  trans-79.7123.9174.3-177.5-14.3000109.3K507 E508 V509N505-K507 PolarHBondContact O-N 3.12Å; N505-K507 VanDerWaalsContact O-N 3.07Å; N505-K507 PolarHBondContact OD1-N 3.07Å; N505-K507 VanDerWaalsContact OD1-N 3.12Å; N505-E508 HydrophobicContact CB-CB 4.07Å; N505-E508 HydrophobicContact CB-CG 4Å; N505-E508 WeakPolarHBondContact O-CA 3.29Å; N505-E508 PolarHBondContact O-N 2.69Å; N505-V509 WeakPolarHBondContact O-CG2 3.4Å; N505-V509 PolarHBondContact O-N 2.84Å
506I65.8Low70.5Confident100 Ų10095.7 Ų95.751%0.51348%0.483SS..Hα-helixtrans-48.4-42.3-179.5-50.3-167.8000111.5I500 H510I500-I506 HydrophobicContact CD1-CB 4.09Å; I500-I506 HydrophobicContact CD1-CD1 4.05Å; I500-I506 HydrophobicContact CD1-CG1 3.59Å; I500-I506 HydrophobicContact CD1-CG2 4.01Å; I506-H510 PolarHBondContact O-N 3.15Å; I506-H510 VanDerWaalsContact O-N 3.15Å; I506-H510 PolarHBondContact O-ND1 2.87Å
507K61.6Low68.5Low162 Ų16296.8 Ų96.870%0.70449%0.49SS*.Hα-helixtrans-67.5-41.2179.5-68-173.8177.8-177.80112N505 L511N505-K507 PolarHBondContact O-N 3.12Å; N505-K507 VanDerWaalsContact O-N 3.07Å; N505-K507 PolarHBondContact OD1-N 3.07Å; N505-K507 VanDerWaalsContact OD1-N 3.12Å; K507-L511 VanDerWaalsContact O-CB 3.32Å; K507-L511 WeakPolarHBondContact O-CB 3.5Å; K507-L511 WeakPolarHBondContact O-CD1 3.49Å; K507-L511 WeakPolarHBondContact O-CG 3.2Å; K507-L511 PolarHBondContact O-N 3.29Å
508E61.1Low66.4Low90 Ų90102.9 Ų102.942%0.42152%0.52SS..Hα-helixtrans-69.6-37.1178.1-70.7-174.5-167.400112.4N505 L511 R512N505-E508 HydrophobicContact CB-CB 4.07Å; N505-E508 HydrophobicContact CB-CG 4Å; N505-E508 WeakPolarHBondContact O-CA 3.29Å; N505-E508 PolarHBondContact O-N 2.69Å; E508-L511 PolarHBondContact O-N 3.27Å; E508-R512 WeakPolarHBondContact O-CB 3.45Å; E508-R512 VanDerWaalsContact O-CG 3.28Å; E508-R512 WeakPolarHBondContact O-CG 3.28Å; E508-R512 PolarHBondContact O-N 2.92Å; E508-R512 IonicContact OE2-NH2 3.59Å
509V60.1Low65Low1 Ų1104.2 Ų104.21%0.00652%0.519CS..Hα-helixtrans-60.9-48.3175.4176.30000110.3K128 E504 N505 E513K128-V509 HydrophobicContact CD-CG1 4.16Å; E504-V509 HydrophobicContact CB-CG2 3.85Å; E504-V509 HydrophobicContact CG-CG2 4.42Å; E504-V509 VanDerWaalsContact OE2-CG2 3.29Å; E504-V509 WeakPolarHBondContact OE2-CG2 3.33Å; N505-V509 WeakPolarHBondContact O-CG2 3.4Å; N505-V509 PolarHBondContact O-N 2.84Å; V509-E513 WeakPolarHBondContact O-CG 3.32Å; V509-E513 PolarHBondContact O-N 2.9Å; V509-E513 VanDerWaalsContact O-N 3.14Å
510H64.8Low63.8Low115 Ų115102.6 Ų102.653%0.53252%0.52SS..Hα-helixtrans-66.2-41.9178.9-75.367.5000111.9I506 E513 H514I506-H510 PolarHBondContact O-N 3.15Å; I506-H510 VanDerWaalsContact O-N 3.15Å; I506-H510 PolarHBondContact O-ND1 2.87Å; H510-E513 PolarHBondContact O-N 3.14Å; H510-H514 WeakPolarHBondContact O-CB 3.48Å; H510-H514 PolarHBondContact O-N 3.31Å
511L59.9Low62.5Low97 Ų97105.7 Ų105.751%0.50854%0.536SS..Hα-helixtrans-63.2-47.4177.2-76.4165.1000111.6K507 E508 E513 H514 F515K507-L511 VanDerWaalsContact O-CB 3.32Å; K507-L511 WeakPolarHBondContact O-CB 3.5Å; K507-L511 WeakPolarHBondContact O-CD1 3.49Å; K507-L511 WeakPolarHBondContact O-CG 3.2Å; K507-L511 PolarHBondContact O-N 3.29Å; E508-L511 PolarHBondContact O-N 3.27Å; L511-E513 PolarHBondContact O-N 3.44Å; L511-H514 PolarHBondContact O-N 3.36Å; L511-F515 HydrophobicContact CD2-CE2 4.34Å; L511-F515 WeakPolarHBondContact O-CD2 3.18Å; L511-F515 PolarHBondContact O-N 3.1Å
512R61.7Low61.5Low137 Ų137110.3 Ų110.352%0.51756%0.556SS.*Hα-helixtrans-62.3-30.6178.4-74.4178.2-173.6178.76.7112.8E508 R516E508-R512 WeakPolarHBondContact O-CB 3.45Å; E508-R512 VanDerWaalsContact O-CG 3.28Å; E508-R512 WeakPolarHBondContact O-CG 3.28Å; E508-R512 PolarHBondContact O-N 2.92Å; E508-R512 IonicContact OE2-NH2 3.59Å; R512-R516 WeakPolarHBondContact O-CG 3.41Å; R512-R516 PolarHBondContact O-N 2.93Å
513E63.4Low61.1Low79 Ų79109.2 Ų109.237%0.36954%0.542SS..Hα-helixtrans-75-42.2174.6-75.2180-177.400111.7K128 V509 H510 L511 F515 R516 S517K128-E513 IonicContact NZ-OE1 2.69Å; K128-E513 PolarHBondContact NZ-OE1 2.97Å; V509-E513 WeakPolarHBondContact O-CG 3.32Å; V509-E513 PolarHBondContact O-N 2.9Å; V509-E513 VanDerWaalsContact O-N 3.14Å; H510-E513 PolarHBondContact O-N 3.14Å; L511-E513 PolarHBondContact O-N 3.44Å; E513-F515 VanDerWaalsContact C-N 3.31Å; E513-F515 PolarHBondContact O-N 2.97Å; E513-R516 PolarHBondContact O-N 3.2Å; E513-R516 VanDerWaalsContact O-N 3.1Å; E513-S517 PolarHBondContact O-N 3.36Å; E513-S517 VanDerWaalsContact O-N 3.09Å; E513-S517 PolarHBondContact O-OG 3.39Å
514H59.8Low60.6Low120 Ų120111.1 Ų111.156%0.55652%0.523SS*.Hα-helixtrans-61-39.5175.5-15866.6000112.3H510 L511 R516 S517 L518H510-H514 WeakPolarHBondContact O-CB 3.48Å; H510-H514 PolarHBondContact O-N 3.31Å; L511-H514 PolarHBondContact O-N 3.36Å; H514-R516 VanDerWaalsContact C-N 3.35Å; H514-S517 PolarHBondContact O-N 3.49Å; H514-S517 PolarHBondContact O-OG 2.95Å; H514-L518 PolarHBondContact O-N 3.09Å
515F59Low60.5Low146 Ų146114.4 Ų114.464%0.6454%0.538SS*.Hα-helixtrans-75.8-14.6175.4-79.3-70000114.8L511 E513L511-F515 HydrophobicContact CD2-CE2 4.34Å; L511-F515 WeakPolarHBondContact O-CD2 3.18Å; L511-F515 PolarHBondContact O-N 3.1Å; E513-F515 VanDerWaalsContact C-N 3.31Å; E513-F515 PolarHBondContact O-N 2.97Å
516R59Low60.2Low209 Ų209117.1 Ų117.179%0.78955%0.547SS*.Hα-helixtrans-91.8-19.5173.1-83.1-176.5177.6-172.9-0.3113R512 E513 H514R512-R516 WeakPolarHBondContact O-CG 3.41Å; R512-R516 PolarHBondContact O-N 2.93Å; E513-R516 PolarHBondContact O-N 3.2Å; E513-R516 VanDerWaalsContact O-N 3.1Å; H514-R516 VanDerWaalsContact C-N 3.35Å
517S55.7Low59.7Low95 Ų95118.5 Ų118.566%0.66455%0.55SS**Hα-helixtrans-89.1-16.9176.159.10000114E513 H514E513-S517 PolarHBondContact O-N 3.36Å; E513-S517 VanDerWaalsContact O-N 3.09Å; E513-S517 PolarHBondContact O-OG 3.39Å; H514-S517 PolarHBondContact O-N 3.49Å; H514-S517 PolarHBondContact O-OG 2.95Å
518L50.4Low59.5Low171 Ų171114.5 Ų114.590%0.89554%0.536SS*.  trans-850163.7-72.6164.8000108.9H514H514-L518 PolarHBondContact O-N 3.09Å

Retrieved 518 of 518 residues in 472.6 ms (Link to these results)