A0A077Z2V1_TRITR Loading...

Uncharacterized protein

AlphaFold DB , UniProt , Accession A0A077Z2V1, Species TRITR (Trichuris trichiura, Whipworm), Gene n/a, Length 448 aa.

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Site Residue pLDDT pLDDT confidence pLDDT10 pLDDT10 confidence SASA SASA [Ų] SASA10 SASA10 [Ų] RSA RSA unformatted RSA10 RSA10 unformatted Surface Surface10 (not used) Disorder (not used) Disorder Sec. str. Secondary structure Isomer Phi (φ) Psi (ψ) Omega (ω) Chi 1 (χ1) Chi 2 (χ2) Chi 3 (χ3) Chi 4 (χ4) Chi 5 (χ5) Tau (τ) Contacts (colored by PAE) Contact details
1M41.9Very low81.3Confident233 Ų23390.7 Ų90.7100%1.14850%0.497SS*.  01290-63.8178.8-162.200106.1V3M1-V3 PolarHBondContact O-N 3.38Å
2A57.8Low82.6Confident109 Ų10983.2 Ų83.290%0.90146%0.456SS*.  trans-64.9109.2173.700000107.1D4A2-D4 PolarHBondContact O-N 2.84Å
3V68.4Low83.8Confident82 Ų8276.8 Ų76.850%0.49742%0.421SS..  trans-73121179.3-169.50000107.5M1 H5 L8M1-V3 PolarHBondContact O-N 3.38Å; V3-H5 PolarHBondContact O-N 2.94Å; V3-H5 VanDerWaalsContact O-N 3.08Å; V3-H5 PolarHBondContact O-ND1 3.02Å; V3-L8 HydrophobicContact CB-CD1 4.09Å; V3-L8 HydrophobicContact CG1-CD1 3.27Å; V3-L8 HydrophobicContact CG1-CD2 4.01Å; V3-L8 HydrophobicContact CG1-CG 3.4Å; V3-L8 VanDerWaalsContact CG1-CG 3.4Å
4D86.1Confident84.7Confident91 Ų9182.4 Ų82.449%0.48744%0.439SS..  trans-64.3111.5175.8-177.8-3.9000108.7A2 A6 E7 L8A2-D4 PolarHBondContact O-N 2.84Å; D4-A6 PolarHBondContact O-N 2.72Å; D4-A6 WeakPolarHBondContact OD1-CB 3.28Å; D4-A6 PolarHBondContact OD1-N 3.03Å; D4-E7 HydrophobicContact CB-CB 3.91Å; D4-E7 PolarHBondContact O-N 2.69Å; D4-E7 VanDerWaalsContact O-N 3.12Å; D4-L8 PolarHBondContact O-N 3.16Å
5H87.1Confident85.6Confident70 Ų7077.3 Ų77.332%0.32441%0.413SS..Hα-helixtrans-60.7-32.9-179.2-75.856000111.4V3 L9V3-H5 PolarHBondContact O-N 2.94Å; V3-H5 VanDerWaalsContact O-N 3.08Å; V3-H5 PolarHBondContact O-ND1 3.02Å; H5-L9 VanDerWaalsContact O-CB 3.26Å; H5-L9 WeakPolarHBondContact O-CB 3.38Å; H5-L9 PolarHBondContact O-N 2.93Å
6A87.9Confident86.4Confident46 Ų4672.5 Ų72.538%0.3839%0.387SS..Hα-helixtrans-70-36.7178.200000111.2D4 K10D4-A6 PolarHBondContact O-N 2.72Å; D4-A6 WeakPolarHBondContact OD1-CB 3.28Å; D4-A6 PolarHBondContact OD1-N 3.03Å; A6-K10 VanDerWaalsContact O-CG 3.29Å; A6-K10 WeakPolarHBondContact O-CG 3.34Å; A6-K10 PolarHBondContact O-N 3.19Å; A6-K10 VanDerWaalsContact O-N 3.07Å
7E90.4Very high87.1Confident113 Ų11370.6 Ų70.653%0.52838%0.381SS..Hα-helixtrans-67.6-47.6174.6-169.2178.9-175.600111.2D4 L9 K10 L11D4-E7 HydrophobicContact CB-CB 3.91Å; D4-E7 PolarHBondContact O-N 2.69Å; D4-E7 VanDerWaalsContact O-N 3.12Å; E7-L9 VanDerWaalsContact C-N 3.28Å; E7-L9 PolarHBondContact O-N 2.71Å; E7-K10 WeakPolarHBondContact O-CB 3.35Å; E7-K10 PolarHBondContact O-N 3.08Å; E7-K10 VanDerWaalsContact O-N 3.17Å; E7-L11 HydrophobicContact CG-CD1 4.36Å; E7-L11 WeakPolarHBondContact O-CG 3.2Å; E7-L11 PolarHBondContact O-N 3.3Å
8L92.2Very high87.7Confident15 Ų1568.7 Ų68.78%0.07937%0.373CS..Hα-helixtrans-57.8-41.5174.7-82178.3000112.2V3 D4 L11 T12 L306 L309 L356V3-L8 HydrophobicContact CB-CD1 4.09Å; V3-L8 HydrophobicContact CG1-CD1 3.27Å; V3-L8 HydrophobicContact CG1-CD2 4.01Å; V3-L8 HydrophobicContact CG1-CG 3.4Å; V3-L8 VanDerWaalsContact CG1-CG 3.4Å; D4-L8 PolarHBondContact O-N 3.16Å; L8-L11 PolarHBondContact O-N 3.26Å; L8-T12 WeakPolarHBondContact O-CB 3.44Å; L8-T12 PolarHBondContact O-N 2.95Å; L8-T12 PolarHBondContact O-OG1 2.7Å; L8-L306 HydrophobicContact CD1-CD2 4.46Å; L8-L309 HydrophobicContact CD2-CD2 4.34Å; L8-L356 HydrophobicContact CB-CD1 4.09Å; L8-L356 HydrophobicContact CB-CD2 4.09Å; L8-L356 HydrophobicContact CD1-CD2 4.26Å
9L93.8Very high88.2Confident19 Ų1965.1 Ų65.110%0.09935%0.354CS..Hα-helixtrans-61.7-46.1177.3178.559000111.1H5 E7 L11 T12 I13 L62 I353 L356 A357H5-L9 VanDerWaalsContact O-CB 3.26Å; H5-L9 WeakPolarHBondContact O-CB 3.38Å; H5-L9 PolarHBondContact O-N 2.93Å; E7-L9 VanDerWaalsContact C-N 3.28Å; E7-L9 PolarHBondContact O-N 2.71Å; L9-L11 PolarHBondContact O-N 3.24Å; L9-T12 PolarHBondContact O-N 2.93Å; L9-I13 HydrophobicContact CD1-CD1 3.97Å; L9-I13 HydrophobicContact CD1-CG1 4.27Å; L9-I13 HydrophobicContact CG-CD1 4Å; L9-I13 VanDerWaalsContact O-CG1 3.29Å; L9-I13 WeakPolarHBondContact O-CG1 3.43Å; L9-I13 PolarHBondContact O-N 3.32Å; L9-L62 HydrophobicContact CD2-CD1 3.93Å; L9-L62 HydrophobicContact CD2-CD2 3.7Å; L9-L62 HydrophobicContact CD2-CG 4.46Å; L9-L62 HydrophobicContact CG-CD1 4.38Å; L9-I353 HydrophobicContact CD1-CB 4.3Å; L9-I353 HydrophobicContact CD1-CG1 4.39Å; L9-I353 HydrophobicContact CD1-CG2 3.93Å; L9-L356 HydrophobicContact CB-CB 4.23Å; L9-L356 HydrophobicContact CB-CD1 4.4Å; L9-L356 HydrophobicContact CD1-CB 4.07Å; L9-A357 HydrophobicContact CD2-CB 4.38Å
10K93.7Very high88.7Confident140 Ų14062.4 Ų62.461%0.60934%0.339SS*.Hα-helixtrans-60.6-44175.6-73.3170.4-176.3172.40112A6 E7 I13 K14A6-K10 VanDerWaalsContact O-CG 3.29Å; A6-K10 WeakPolarHBondContact O-CG 3.34Å; A6-K10 PolarHBondContact O-N 3.19Å; A6-K10 VanDerWaalsContact O-N 3.07Å; E7-K10 WeakPolarHBondContact O-CB 3.35Å; E7-K10 PolarHBondContact O-N 3.08Å; E7-K10 VanDerWaalsContact O-N 3.17Å; K10-I13 PolarHBondContact O-N 2.99Å; K10-K14 WeakPolarHBondContact O-CB 3.26Å; K10-K14 PolarHBondContact O-N 2.93Å
11L95.3Very high89.1Confident80 Ų8062.8 Ų62.842%0.41935%0.346SS..Hα-helixtrans-62.9-42.9176.9-71.5173.4000111.6E7 L8 L9 K14 A15 L313E7-L11 HydrophobicContact CG-CD1 4.36Å; E7-L11 WeakPolarHBondContact O-CG 3.2Å; E7-L11 PolarHBondContact O-N 3.3Å; L8-L11 PolarHBondContact O-N 3.26Å; L9-L11 PolarHBondContact O-N 3.24Å; L11-K14 PolarHBondContact O-N 3.38Å; L11-A15 WeakPolarHBondContact O-CB 2.95Å; L11-A15 PolarHBondContact O-N 3.25Å; L11-L313 HydrophobicContact CB-CD1 4.39Å
12T97Very high91.8Very high0 Ų052.1 Ų52.10%029%0.294CS..Hα-helixtrans-66-41.7179.3-50.50000111.5L8 L9 A15 L16 L309 L349 I353L8-T12 WeakPolarHBondContact O-CB 3.44Å; L8-T12 PolarHBondContact O-N 2.95Å; L8-T12 PolarHBondContact O-OG1 2.7Å; L9-T12 PolarHBondContact O-N 2.93Å; T12-A15 PolarHBondContact O-N 3.21Å; T12-L16 PolarHBondContact O-N 3.43Å; T12-L309 HydrophobicContact CG2-CD1 4.34Å; T12-L349 HydrophobicContact CG2-CB 4.26Å; T12-L349 HydrophobicContact CG2-CD2 3.72Å; T12-I353 HydrophobicContact CG2-CD1 4.31Å; T12-I353 HydrophobicContact CG2-CG1 3.62Å
13I97.1Very high93.6Very high1 Ų147 Ų471%0.00525%0.251CS..Hα-helixtrans-63.3-44.2173.8-66.8166.4000110.4L9 K10 A15 L16 C17 L62 Q65 L66 V69 I353L9-I13 HydrophobicContact CD1-CD1 3.97Å; L9-I13 HydrophobicContact CD1-CG1 4.27Å; L9-I13 HydrophobicContact CG-CD1 4Å; L9-I13 VanDerWaalsContact O-CG1 3.29Å; L9-I13 WeakPolarHBondContact O-CG1 3.43Å; L9-I13 PolarHBondContact O-N 3.32Å; K10-I13 PolarHBondContact O-N 2.99Å; I13-A15 VanDerWaalsContact C-N 3.34Å; I13-A15 PolarHBondContact O-N 2.7Å; I13-L16 PolarHBondContact O-N 2.76Å; I13-C17 PolarHBondContact O-N 3.39Å; I13-C17 PolarHBondContact O-SG 2.92Å; I13-L62 HydrophobicContact CD1-CD1 3.58Å; I13-Q65 HydrophobicContact CG2-CG 4.24Å; I13-L66 HydrophobicContact CD1-CD2 4.14Å; I13-L66 HydrophobicContact CG1-CD2 4.38Å; I13-V69 HydrophobicContact CG2-CG2 4.28Å; I13-I353 HydrophobicContact CG1-CD1 3.88Å; I13-I353 HydrophobicContact CG1-CG1 4.03Å; I13-I353 HydrophobicContact CG1-CG2 4.4Å
14K97.3Very high95Very high154 Ų15446.3 Ų46.367%0.6725%0.25SC*.Hα-helixtrans-60.7-42.9177-174.8-178.5177.6-174.70111.7K10 L11 C17 S18K10-K14 WeakPolarHBondContact O-CB 3.26Å; K10-K14 PolarHBondContact O-N 2.93Å; L11-K14 PolarHBondContact O-N 3.38Å; K14-C17 PolarHBondContact O-N 3.06Å; K14-S18 PolarHBondContact O-N 3.45Å
15A97.9Very high95.5Very high6 Ų648.3 Ų48.35%0.0526%0.261CS..Hα-helixtrans-60.3-45.4175.500000111.3L11 T12 I13 C17 S18 V19 L313 Q316 L349L11-A15 WeakPolarHBondContact O-CB 2.95Å; L11-A15 PolarHBondContact O-N 3.25Å; T12-A15 PolarHBondContact O-N 3.21Å; I13-A15 VanDerWaalsContact C-N 3.34Å; I13-A15 PolarHBondContact O-N 2.7Å; A15-C17 PolarHBondContact O-N 3.02Å; A15-S18 WeakPolarHBondContact O-CB 3.06Å; A15-S18 PolarHBondContact O-N 3.44Å; A15-S18 VanDerWaalsContact O-N 3.17Å; A15-V19 PolarHBondContact O-N 3.07Å; A15-L313 HydrophobicContact CB-CD2 3.6Å; A15-Q316 PolarHBondContact O-NE2 3.24Å; A15-L349 HydrophobicContact CB-CD1 4.09Å; A15-L349 HydrophobicContact CB-CD2 4.35Å
16L98.3Very high95.9Very high1 Ų147.9 Ų47.91%0.00526%0.259CS..Hα-helixtrans-60.7-45.7175.6-179.762.6000111.8T12 I13 S18 V19 L20 I41 V69 L349 V350 I353T12-L16 PolarHBondContact O-N 3.43Å; I13-L16 PolarHBondContact O-N 2.76Å; L16-S18 VanDerWaalsContact C-N 3.25Å; L16-S18 PolarHBondContact O-N 2.99Å; L16-V19 WeakPolarHBondContact O-CB 3.02Å; L16-V19 PolarHBondContact O-N 2.99Å; L16-V19 VanDerWaalsContact O-N 3.16Å; L16-L20 HydrophobicContact CD1-CG 4.49Å; L16-L20 HydrophobicContact CG-CD1 4.32Å; L16-L20 WeakPolarHBondContact O-CG 3.31Å; L16-L20 PolarHBondContact O-N 3.06Å; L16-I41 HydrophobicContact CD1-CD1 4.07Å; L16-I41 HydrophobicContact CD2-CG2 4.22Å; L16-V69 HydrophobicContact CD2-CG1 4.1Å; L16-L349 HydrophobicContact CB-CD1 4.44Å; L16-V350 HydrophobicContact CD1-CG2 4.34Å; L16-V350 HydrophobicContact CD2-CG2 3.56Å; L16-I353 HydrophobicContact CB-CD1 4.29Å; L16-I353 HydrophobicContact CD2-CD1 3.63Å
17C98.3Very high96.2Very high41 Ų4147.2 Ų47.228%0.27725%0.251SS..Hα-helixtrans-59.1-37.2175.4-67.80000112.5I13 K14 A15 L20 S21I13-C17 PolarHBondContact O-N 3.39Å; I13-C17 PolarHBondContact O-SG 2.92Å; K14-C17 PolarHBondContact O-N 3.06Å; A15-C17 PolarHBondContact O-N 3.02Å; C17-L20 PolarHBondContact O-N 2.99Å; C17-S21 WeakPolarHBondContact O-CB 3.04Å; C17-S21 PolarHBondContact O-N 3.12Å; C17-S21 PolarHBondContact O-OG 3.28Å
18S98.1Very high96.3Very high35 Ų3545.2 Ų45.225%0.24525%0.25CC..Hα-helixtrans-64.3-44.2174.9-163.80000111.5K14 A15 L16 L20 S21 F22 G320K14-S18 PolarHBondContact O-N 3.45Å; A15-S18 WeakPolarHBondContact O-CB 3.06Å; A15-S18 PolarHBondContact O-N 3.44Å; A15-S18 VanDerWaalsContact O-N 3.17Å; L16-S18 VanDerWaalsContact C-N 3.25Å; L16-S18 PolarHBondContact O-N 2.99Å; S18-L20 PolarHBondContact O-N 3.39Å; S18-S21 PolarHBondContact O-N 3.27Å; S18-F22 PolarHBondContact O-N 2.99Å; S18-G320 WeakPolarHBondContact OG-CA 3.29Å
19V97.7Very high96.4Very high0 Ų049.2 Ų49.20%027%0.268CS..Hα-helixtrans-58.3-48.1173.1178.10000111.3A15 L16 S21 F22 C23 Q316 G320 Y322 T342 L349A15-V19 PolarHBondContact O-N 3.07Å; L16-V19 WeakPolarHBondContact O-CB 3.02Å; L16-V19 PolarHBondContact O-N 2.99Å; L16-V19 VanDerWaalsContact O-N 3.16Å; V19-S21 VanDerWaalsContact C-N 3.29Å; V19-S21 PolarHBondContact O-N 3.19Å; V19-F22 WeakPolarHBondContact O-CB 3.02Å; V19-F22 PolarHBondContact O-N 3.39Å; V19-C23 PolarHBondContact O-N 3.19Å; V19-C23 PolarHBondContact O-SG 2.67Å; V19-C23 VanDerWaalsContact O-SG 3.4Å; V19-Q316 VanDerWaalsContact CG2-NE2 3.31Å; V19-G320 WeakPolarHBondContact CA-O 3.02Å; V19-G320 VanDerWaalsContact CG2-O 3.28Å; V19-G320 WeakPolarHBondContact CG2-O 3.4Å; V19-Y322 HydrophobicContact CG2-CD2 4.38Å; V19-Y322 HydrophobicContact CG2-CE2 3.86Å; V19-T342 HydrophobicContact CB-CG2 4.49Å; V19-T342 HydrophobicContact CG1-CG2 3.38Å; V19-L349 HydrophobicContact CG2-CD1 4.23Å
20L97.8Very high96.3Very high12 Ų1248.3 Ų48.36%0.06326%0.263CS..Hα-helixtrans-62.9-37.9-178.8-65.4175.1000111.7L16 C17 S18 C23 S24 F38 V69 V73 L76L16-L20 HydrophobicContact CD1-CG 4.49Å; L16-L20 HydrophobicContact CG-CD1 4.32Å; L16-L20 WeakPolarHBondContact O-CG 3.31Å; L16-L20 PolarHBondContact O-N 3.06Å; C17-L20 PolarHBondContact O-N 2.99Å; S18-L20 PolarHBondContact O-N 3.39Å; L20-C23 PolarHBondContact O-N 3.01Å; L20-S24 WeakPolarHBondContact O-CB 3.24Å; L20-S24 PolarHBondContact O-N 2.72Å; L20-F38 HydrophobicContact CD2-CD1 4.33Å; L20-F38 HydrophobicContact CD2-CE1 4.5Å; L20-V69 HydrophobicContact CD1-CG1 3.77Å; L20-V73 HydrophobicContact CD1-CB 4.15Å; L20-V73 HydrophobicContact CD2-CB 4.05Å; L20-V73 HydrophobicContact CD2-CG2 3.76Å; L20-L76 HydrophobicContact CB-CD2 4.5Å; L20-L76 HydrophobicContact CD2-CD2 3.91Å
21S97.7Very high96.1Very high70 Ų7044.8 Ų44.849%0.4925%0.249SC..Hα-helixtrans-65.1-43.7175.2-56.10000111.4C17 S18 V19 S24 N25C17-S21 WeakPolarHBondContact O-CB 3.04Å; C17-S21 PolarHBondContact O-N 3.12Å; C17-S21 PolarHBondContact O-OG 3.28Å; S18-S21 PolarHBondContact O-N 3.27Å; V19-S21 VanDerWaalsContact C-N 3.29Å; V19-S21 PolarHBondContact O-N 3.19Å; S21-S24 PolarHBondContact O-N 3.02Å; S21-N25 PolarHBondContact O-N 3.21Å; S21-N25 VanDerWaalsContact O-N 3.16Å; S21-N25 PolarHBondContact O-ND2 3.12Å
22F97.3Very high95.7Very high9 Ų941 Ų414%0.03923%0.229CC..Hα-helixtrans-57.4-52173.7172.7-103.3000111.6S18 V19 S24 N25 H26 T319 C321 C337 M339 T342S18-F22 PolarHBondContact O-N 2.99Å; V19-F22 WeakPolarHBondContact O-CB 3.02Å; V19-F22 PolarHBondContact O-N 3.39Å; F22-S24 VanDerWaalsContact C-N 3.29Å; F22-S24 PolarHBondContact O-N 3.14Å; F22-N25 PolarHBondContact O-N 2.68Å; F22-N25 VanDerWaalsContact O-N 3.12Å; F22-H26 AromaticContact CD2-CE1 3.66Å; F22-H26 AromaticContact CD2-ND1 3.61Å; F22-H26 AromaticContact CE2-CE1 3.36Å; F22-H26 WeakPolarHBondContact CE2-CE1 3.48Å; F22-H26 AromaticContact CE2-ND1 3.44Å; F22-H26 WeakPolarHBondContact CE2-ND1 3.31Å; F22-H26 AromaticContact CE2-NE2 3.9Å; F22-H26 AromaticContact CZ-ND1 3.93Å; F22-H26 PolarHBondContact O-N 3.41Å; F22-H26 VanDerWaalsContact O-N 3.17Å; F22-H26 PolarHBondContact O-ND1 3.37Å; F22-T319 WeakPolarHBondContact CB-O 3.38Å; F22-C321 HydrophobicContact CD1-CB 3.64Å; F22-C321 HydrophobicContact CD2-CB 3.84Å; F22-C321 HydrophobicContact CE1-CB 3.48Å; F22-C321 VanDerWaalsContact CE1-CB 3.48Å; F22-C321 HydrophobicContact CE2-CB 3.71Å; F22-C321 HydrophobicContact CG-CB 3.82Å; F22-C321 HydrophobicContact CZ-CB 3.54Å; F22-C337 HydrophobicContact CE1-CB 4.34Å; F22-C337 HydrophobicContact CE2-CB 4.1Å; F22-C337 HydrophobicContact CZ-CB 3.56Å; F22-M339 HydrophobicContact CD1-SD 4.44Å; F22-M339 HydrophobicContact CE1-SD 3.59Å; F22-M339 VanDerWaalsContact CE1-SD 3.59Å; F22-M339 HydrophobicContact CZ-SD 4.31Å; F22-T342 HydrophobicContact CD1-CG2 4.09Å; F22-T342 HydrophobicContact CE1-CG2 4.39Å
23C96.9Very high95Very high1 Ų141 Ų411%0.00723%0.229CC..Hα-helixtrans-65.3-32-179.1-67.90000112.7V19 L20 N25 H26 S27 F38 L76V19-C23 PolarHBondContact O-N 3.19Å; V19-C23 PolarHBondContact O-SG 2.67Å; V19-C23 VanDerWaalsContact O-SG 3.4Å; L20-C23 PolarHBondContact O-N 3.01Å; C23-N25 VanDerWaalsContact C-N 3.32Å; C23-H26 CarbonylContact O-C 3.59Å; C23-H26 VanDerWaalsContact O-C 3.27Å; C23-H26 PolarHBondContact O-N 2.98Å; C23-S27 WeakPolarHBondContact O-CA 3.48Å; C23-S27 PolarHBondContact O-N 3.23Å; C23-F38 HydrophobicContact CB-CE1 4.14Å; C23-F38 HydrophobicContact CB-CE2 4.41Å; C23-F38 HydrophobicContact CB-CZ 3.55Å; C23-L76 HydrophobicContact CB-CD2 3.82Å
24S96.6Very high94.7Very high68 Ų6841 Ų4148%0.47623%0.229SC..Hα-helixtrans-64-37.6173.1-170.90000112.4L20 S21 F22 H26L20-S24 WeakPolarHBondContact O-CB 3.24Å; L20-S24 PolarHBondContact O-N 2.72Å; S21-S24 PolarHBondContact O-N 3.02Å; F22-S24 VanDerWaalsContact C-N 3.29Å; F22-S24 PolarHBondContact O-N 3.14Å; S24-H26 VanDerWaalsContact C-N 3.27Å; S24-H26 PolarHBondContact O-N 3.28Å
25N96.7Very high94.4Very high133 Ų13333.6 Ų33.671%0.71120%0.197SC*.Hα-helixtrans-77.1-14.6177.5-66.9-25.4000113.1S21 F22 C23S21-N25 PolarHBondContact O-N 3.21Å; S21-N25 VanDerWaalsContact O-N 3.16Å; S21-N25 PolarHBondContact O-ND2 3.12Å; F22-N25 PolarHBondContact O-N 2.68Å; F22-N25 VanDerWaalsContact O-N 3.12Å; C23-N25 VanDerWaalsContact C-N 3.32Å
26H95.7Very high93.9Very high62 Ų6233.3 Ų33.329%0.28720%0.195SC..THydrogen-bonded Turntrans-124.236.4-179.2-57.478.9000110.9F22 C23 S24 S28 E29F22-H26 AromaticContact CD2-CE1 3.66Å; F22-H26 AromaticContact CD2-ND1 3.61Å; F22-H26 AromaticContact CE2-CE1 3.36Å; F22-H26 WeakPolarHBondContact CE2-CE1 3.48Å; F22-H26 AromaticContact CE2-ND1 3.44Å; F22-H26 WeakPolarHBondContact CE2-ND1 3.31Å; F22-H26 AromaticContact CE2-NE2 3.9Å; F22-H26 AromaticContact CZ-ND1 3.93Å; F22-H26 PolarHBondContact O-N 3.41Å; F22-H26 VanDerWaalsContact O-N 3.17Å; F22-H26 PolarHBondContact O-ND1 3.37Å; C23-H26 CarbonylContact O-C 3.59Å; C23-H26 VanDerWaalsContact O-C 3.27Å; C23-H26 PolarHBondContact O-N 2.98Å; S24-H26 VanDerWaalsContact C-N 3.27Å; S24-H26 PolarHBondContact O-N 3.28Å; H26-S28 PolarHBondContact O-N 3.15Å; H26-S28 VanDerWaalsContact O-N 3.15Å; H26-E29 IonicContact CD2-OE1 3.06Å; H26-E29 PolarHBondContact O-N 3.49Å
27S93.4Very high93.5Very high32 Ų3233.3 Ų33.322%0.22420%0.195CC..G310 helixtrans-59.6-29.4-174.564.60000113.1C23 E29 V30 H83C23-S27 WeakPolarHBondContact O-CA 3.48Å; C23-S27 PolarHBondContact O-N 3.23Å; S27-E29 VanDerWaalsContact C-N 3.26Å; S27-E29 PolarHBondContact O-N 2.86Å; S27-V30 WeakPolarHBondContact O-CB 3.42Å; S27-V30 WeakPolarHBondContact O-CG2 3.13Å; S27-V30 PolarHBondContact O-N 3.29Å; S27-H83 PolarHBondContact O-CD2 3.44Å; S27-H83 PolarHBondContact OG-NE2 3.48Å
28S93.5Very high93.3Very high70 Ų7031.3 Ų31.349%0.4918%0.181SC..G310 helixtrans-68.9-20.3176.355.90000114H26 N87H26-S28 PolarHBondContact O-N 3.15Å; H26-S28 VanDerWaalsContact O-N 3.15Å; S28-N87 PolarHBondContact O-ND2 2.96Å
29E93.8Very high93Very high100 Ų10029.9 Ų29.947%0.46717%0.17SC..G310 helixtrans-94-3.5178.2-61.3-175.7-154.200112.6H26 S27 Q31 M339H26-E29 IonicContact CD2-OE1 3.06Å; H26-E29 PolarHBondContact O-N 3.49Å; S27-E29 VanDerWaalsContact C-N 3.26Å; S27-E29 PolarHBondContact O-N 2.86Å; E29-Q31 PolarHBondContact O-N 3.23Å; E29-M339 HydrophobicContact CB-CG 4.14Å
30V92Very high92.6Very high0 Ų030.3 Ų30.30%017%0.172CC..  trans-66.4127.3-179.7178.50000109.7S27 L35 F38 A80 V84 M339S27-V30 WeakPolarHBondContact O-CB 3.42Å; S27-V30 WeakPolarHBondContact O-CG2 3.13Å; S27-V30 PolarHBondContact O-N 3.29Å; V30-L35 HydrophobicContact CG1-CB 4.48Å; V30-F38 HydrophobicContact CG1-CD2 4.46Å; V30-F38 HydrophobicContact CG1-CE2 3.74Å; V30-F38 HydrophobicContact CG2-CE2 4.08Å; V30-A80 HydrophobicContact CB-CB 4.16Å; V30-A80 HydrophobicContact CG1-CB 3.75Å; V30-A80 HydrophobicContact CG2-CB 4.43Å; V30-V84 HydrophobicContact CG1-CG2 4.01Å; V30-V84 WeakPolarHBondContact O-CG2 3.31Å; V30-M339 HydrophobicContact CB-CE 4.36Å; V30-M339 HydrophobicContact CG2-CE 3.67Å
31Q90Very high92.4Very high65 Ų6529.7 Ų29.730%0.30417%0.169SC..  trans-103.5173.3176.3-64.3-180-12.400111E29 S33 S34 L35E29-Q31 PolarHBondContact O-N 3.23Å; Q31-S33 PolarHBondContact O-N 3.4Å; Q31-S34 WeakPolarHBondContact O-CB 3.46Å; Q31-S34 PolarHBondContact O-N 2.86Å; Q31-L35 PolarHBondContact O-N 3.32Å
32S86.8Confident92.3Very high0 Ų026.9 Ų26.90%015%0.148CC..Hα-helixtrans-55.4-35.1177-62.10000113.2L36 V84 D88 L99S32-L36 WeakPolarHBondContact O-CB 3.16Å; S32-L36 PolarHBondContact O-N 2.74Å; S32-V84 WeakPolarHBondContact OG-CG1 2.96Å; S32-D88 VanDerWaalsContact CB-OD2 3.23Å; S32-D88 WeakPolarHBondContact CB-OD2 3.48Å; S32-D88 PolarHBondContact OG-OD2 3.42Å; S32-L99 WeakPolarHBondContact O-CD2 3.32Å
33S82.1Confident92Very high0 Ų026.6 Ų26.60%015%0.148CC..Hα-helixtrans-61.7-47174.242.40000112.3Q31 L36 A37 S199Q31-S33 PolarHBondContact O-N 3.4Å; S33-L36 WeakPolarHBondContact O-CB 2.99Å; S33-L36 PolarHBondContact O-N 2.93Å; S33-A37 PolarHBondContact O-N 2.96Å; S33-S199 WeakPolarHBondContact CA-OG 3.42Å; S33-S199 WeakPolarHBondContact CB-OG 3.45Å; S33-S199 PolarHBondContact N-OG 2.88Å; S33-S199 VanDerWaalsContact N-OG 3.15Å
34S90.1Very high91.7Very high1 Ų127 Ų271%0.00715%0.149CC..Hα-helixtrans-64.8-44.8178.2-54.20000111.2Q31 L36 A37 F38Q31-S34 WeakPolarHBondContact O-CB 3.46Å; Q31-S34 PolarHBondContact O-N 2.86Å; S34-L36 VanDerWaalsContact C-N 3.31Å; S34-L36 PolarHBondContact O-N 3.12Å; S34-A37 WeakPolarHBondContact O-CB 3.21Å; S34-A37 PolarHBondContact O-N 3.16Å; S34-F38 WeakPolarHBondContact O-CD1 3.2Å; S34-F38 WeakPolarHBondContact O-CD2 3.3Å; S34-F38 VanDerWaalsContact O-CG 3.23Å; S34-F38 WeakPolarHBondContact O-CG 3.16Å; S34-F38 PolarHBondContact O-N 2.87Å
35L91.7Very high91.5Very high0 Ų023.7 Ų23.70%013%0.127CC..Hα-helixtrans-61.7-39.9175.2178.559000112V30 Q31 A37 F38 R39 A77 A80 I81 V84 F92 L99V30-L35 HydrophobicContact CG1-CB 4.48Å; Q31-L35 PolarHBondContact O-N 3.32Å; L35-A37 VanDerWaalsContact C-N 3.34Å; L35-A37 PolarHBondContact O-N 3.03Å; L35-F38 PolarHBondContact O-N 2.87Å; L35-R39 HydrophobicContact CD1-CG 4.45Å; L35-R39 WeakPolarHBondContact O-CG 3.17Å; L35-R39 PolarHBondContact O-N 2.87Å; L35-A77 HydrophobicContact CD1-CB 3.93Å; L35-A77 WeakPolarHBondContact CD1-O 3.2Å; L35-A80 HydrophobicContact CD1-CB 4.44Å; L35-I81 HydrophobicContact CD1-CG1 4.46Å; L35-I81 HydrophobicContact CD2-CG1 4.02Å; L35-V84 HydrophobicContact CB-CG2 4.07Å; L35-V84 HydrophobicContact CD2-CB 4.26Å; L35-V84 HydrophobicContact CD2-CG1 4.27Å; L35-V84 HydrophobicContact CD2-CG2 4.1Å; L35-F92 HydrophobicContact CD2-CD2 4.15Å; L35-F92 HydrophobicContact CD2-CE2 3.82Å; L35-L99 HydrophobicContact CD2-CB 3.96Å; L35-L99 HydrophobicContact CD2-CD1 4.47Å; L35-L99 HydrophobicContact CG-CB 4.36Å; L35-L99 HydrophobicContact CG-CD2 4.41Å
36L86.9Confident91.3Very high0 Ų019 Ų190%010%0.104CC..Hα-helixtrans-60.2-45.4174.6179.764.7000111.4S32 S33 S34 F38 R39 F40 L99 Y103 P195 L196S32-L36 WeakPolarHBondContact O-CB 3.16Å; S32-L36 PolarHBondContact O-N 2.74Å; S33-L36 WeakPolarHBondContact O-CB 2.99Å; S33-L36 PolarHBondContact O-N 2.93Å; S34-L36 VanDerWaalsContact C-N 3.31Å; S34-L36 PolarHBondContact O-N 3.12Å; L36-F38 VanDerWaalsContact C-N 3.31Å; L36-F38 PolarHBondContact O-N 3.3Å; L36-R39 PolarHBondContact O-N 3.09Å; L36-F40 WeakPolarHBondContact O-CB 3.49Å; L36-F40 PolarHBondContact O-N 3.21Å; L36-L99 HydrophobicContact CB-CD2 3.65Å; L36-L99 HydrophobicContact CD1-CD2 4.16Å; L36-L99 HydrophobicContact CG-CD2 4.48Å; L36-Y103 HydrophobicContact CD1-CE2 3.53Å; L36-Y103 WeakPolarHBondContact CD1-OH 3.3Å; L36-P195 HydrophobicContact CD1-CG 4.24Å; L36-P195 HydrophobicContact CD2-CB 3.79Å; L36-P195 HydrophobicContact CD2-CG 3.9Å; L36-L196 HydrophobicContact CB-CD1 4.26Å; L36-L196 HydrophobicContact CB-CG 4.24Å; L36-L196 HydrophobicContact CD2-CB 3.51Å; L36-L196 HydrophobicContact CD2-CD1 3.57Å; L36-L196 HydrophobicContact CD2-CG 3.6Å; L36-L196 HydrophobicContact CG-CD1 3.82Å; L36-L196 HydrophobicContact CG-CG 4.15Å
37A90.1Very high90.9Very high0 Ų016.4 Ų16.40%09%0.092CC..Hα-helixtrans-60.1-41.917600000111.4S33 S34 L35 R39 F40 I41 A343 A347S33-A37 PolarHBondContact O-N 2.96Å; S34-A37 WeakPolarHBondContact O-CB 3.21Å; S34-A37 PolarHBondContact O-N 3.16Å; L35-A37 VanDerWaalsContact C-N 3.34Å; L35-A37 PolarHBondContact O-N 3.03Å; A37-R39 PolarHBondContact O-N 3Å; A37-F40 WeakPolarHBondContact O-CB 3.1Å; A37-F40 PolarHBondContact O-N 2.96Å; A37-I41 WeakPolarHBondContact O-CD1 3.36Å; A37-I41 WeakPolarHBondContact O-CG1 3.19Å; A37-I41 PolarHBondContact O-N 3.04Å; A37-A343 HydrophobicContact CB-CB 3.88Å; A37-A347 HydrophobicContact CB-CB 4.39Å
38F94.3Very high90.8Very high0 Ų014.9 Ų14.90%08%0.082CC..Hα-helixtrans-62.9-44177-57-26.6000112.5L20 C23 V30 S34 L35 L36 F40 I41 E42 V73 L76 A77L20-F38 HydrophobicContact CD2-CD1 4.33Å; L20-F38 HydrophobicContact CD2-CE1 4.5Å; C23-F38 HydrophobicContact CB-CE1 4.14Å; C23-F38 HydrophobicContact CB-CE2 4.41Å; C23-F38 HydrophobicContact CB-CZ 3.55Å; V30-F38 HydrophobicContact CG1-CD2 4.46Å; V30-F38 HydrophobicContact CG1-CE2 3.74Å; V30-F38 HydrophobicContact CG2-CE2 4.08Å; S34-F38 WeakPolarHBondContact O-CD1 3.2Å; S34-F38 WeakPolarHBondContact O-CD2 3.3Å; S34-F38 VanDerWaalsContact O-CG 3.23Å; S34-F38 WeakPolarHBondContact O-CG 3.16Å; S34-F38 PolarHBondContact O-N 2.87Å; L35-F38 PolarHBondContact O-N 2.87Å; L36-F38 VanDerWaalsContact C-N 3.31Å; L36-F38 PolarHBondContact O-N 3.3Å; F38-F40 VanDerWaalsContact C-N 3.29Å; F38-F40 PolarHBondContact O-N 3.36Å; F38-I41 HydrophobicContact CD1-CD1 4.4Å; F38-I41 PolarHBondContact O-N 3.16Å; F38-E42 VanDerWaalsContact O-CB 3.29Å; F38-E42 WeakPolarHBondContact O-CB 3.38Å; F38-E42 PolarHBondContact O-N 3.21Å; F38-V73 HydrophobicContact CB-CG2 3.78Å; F38-V73 HydrophobicContact CD1-CG2 4.42Å; F38-V73 HydrophobicContact CG-CG2 4.36Å; F38-V73 WeakPolarHBondContact O-CG2 3.42Å; F38-L76 HydrophobicContact CD1-CD2 4.31Å; F38-L76 HydrophobicContact CD2-CD2 4.2Å; F38-L76 HydrophobicContact CD2-CG 4.11Å; F38-L76 HydrophobicContact CE1-CD2 4.07Å; F38-L76 HydrophobicContact CE2-CD2 3.93Å; F38-L76 HydrophobicContact CE2-CG 4Å; F38-L76 HydrophobicContact CG-CD2 4.41Å; F38-L76 HydrophobicContact CZ-CD2 3.89Å; F38-L76 HydrophobicContact CZ-CG 4.46Å; F38-A77 HydrophobicContact CB-CB 3.94Å
39R92.8Very high90.6Very high4 Ų411.6 Ų11.62%0.0156%0.059CC..Hα-helixtrans-65-33.2175.1-69-53.5-172.6-169.9-4.9113.1L35 L36 A37 E42 G43 N78 L99 Q101 P102 Y103L35-R39 HydrophobicContact CD1-CG 4.45Å; L35-R39 WeakPolarHBondContact O-CG 3.17Å; L35-R39 PolarHBondContact O-N 2.87Å; L36-R39 PolarHBondContact O-N 3.09Å; A37-R39 PolarHBondContact O-N 3Å; R39-E42 WeakPolarHBondContact CD-OE2 3.48Å; R39-E42 IonicContact CZ-OE2 2.73Å; R39-E42 IonicContact NE-OE2 2.7Å; R39-E42 IonicContact NH1-OE1 2.99Å; R39-E42 IonicContact NH1-OE2 3.33Å; R39-E42 PolarHBondContact NH1-OE2 3.47Å; R39-G43 PolarHBondContact O-N 3.17Å; R39-G43 VanDerWaalsContact O-N 3.1Å; R39-N78 PolarHBondContact NH1-OD1 2.69Å; R39-N78 PolarHBondContact NH2-OD1 2.57Å; R39-L99 WeakPolarHBondContact CG-O 3.49Å; R39-L99 PolarHBondContact NE-O 3.06Å; R39-L99 VanDerWaalsContact NE-O 3.08Å; R39-Q101 WeakPolarHBondContact CB-O 3.38Å; R39-P102 WeakPolarHBondContact O-CA 3.45Å; R39-Y103 HydrophobicContact CB-CD2 3.98Å; R39-Y103 HydrophobicContact CB-CE2 3.24Å; R39-Y103 HydrophobicContact CG-CE2 4.44Å; R39-Y103 PolarHBondContact O-N 3.15Å; R39-Y103 VanDerWaalsContact O-N 3.16Å
40F88.9Confident90.4Very high9 Ų914.4 Ų14.44%0.0397%0.066CC..Hα-helixtrans-63.2-53.3170.8175.2-101.2000111.2L36 A37 F38 E42 G43 Q44 Y103 L293 H297 A347 V350L36-F40 WeakPolarHBondContact O-CB 3.49Å; L36-F40 PolarHBondContact O-N 3.21Å; A37-F40 WeakPolarHBondContact O-CB 3.1Å; A37-F40 PolarHBondContact O-N 2.96Å; F38-F40 VanDerWaalsContact C-N 3.29Å; F38-F40 PolarHBondContact O-N 3.36Å; F40-E42 VanDerWaalsContact C-N 3.32Å; F40-E42 PolarHBondContact O-N 2.94Å; F40-G43 PolarHBondContact O-N 3.07Å; F40-Q44 HydrophobicContact CD1-CG 4.38Å; F40-Q44 HydrophobicContact CD2-CG 3.99Å; F40-Q44 HydrophobicContact CE1-CG 4.05Å; F40-Q44 HydrophobicContact CE2-CG 3.58Å; F40-Q44 HydrophobicContact CG-CG 4.37Å; F40-Q44 HydrophobicContact CZ-CG 3.64Å; F40-Q44 VanDerWaalsContact O-CG 3.25Å; F40-Q44 WeakPolarHBondContact O-CG 3.29Å; F40-Q44 PolarHBondContact O-N 2.92Å; F40-Y103 HydrophobicContact CB-CD2 4.06Å; F40-Y103 HydrophobicContact CB-CE2 4.44Å; F40-L293 HydrophobicContact CE1-CD1 4.29Å; F40-H297 AromaticContact CD2-CD2 3.98Å; F40-H297 AromaticContact CD2-NE2 3.84Å; F40-H297 AromaticContact CE2-CD2 3.2Å; F40-H297 WeakPolarHBondContact CE2-CD2 2.9Å; F40-H297 AromaticContact CE2-NE2 3.28Å; F40-H297 VanDerWaalsContact CE2-NE2 3.28Å; F40-H297 WeakPolarHBondContact CE2-NE2 3.12Å; F40-H297 AromaticContact CZ-CD2 3.7Å; F40-A347 HydrophobicContact CD1-CB 3.77Å; F40-A347 HydrophobicContact CE1-CB 4.05Å; F40-V350 HydrophobicContact CE1-CG1 4.3Å
41I93.7Very high90.1Very high0 Ų016.1 Ų16.10%08%0.075CC..Hα-helixtrans-55.5-49.2176.7-64.6158.8000110.5L16 A37 F38 G43 Q44 L45 V73 S346 V350L16-I41 HydrophobicContact CD1-CD1 4.07Å; L16-I41 HydrophobicContact CD2-CG2 4.22Å; A37-I41 WeakPolarHBondContact O-CD1 3.36Å; A37-I41 WeakPolarHBondContact O-CG1 3.19Å; A37-I41 PolarHBondContact O-N 3.04Å; F38-I41 HydrophobicContact CD1-CD1 4.4Å; F38-I41 PolarHBondContact O-N 3.16Å; I41-G43 VanDerWaalsContact C-N 3.31Å; I41-G43 PolarHBondContact O-N 3.03Å; I41-Q44 PolarHBondContact O-N 3.46Å; I41-L45 HydrophobicContact CG2-CD1 3.68Å; I41-L45 HydrophobicContact CG2-CG 4.24Å; I41-L45 VanDerWaalsContact O-CG 3.25Å; I41-L45 WeakPolarHBondContact O-CG 3.41Å; I41-L45 PolarHBondContact O-N 3.48Å; I41-L45 VanDerWaalsContact O-N 3.14Å; I41-V73 HydrophobicContact CB-CG2 4.16Å; I41-V73 HydrophobicContact CG2-CB 4.27Å; I41-V73 HydrophobicContact CG2-CG1 4.09Å; I41-V73 HydrophobicContact CG2-CG2 3.99Å; I41-S346 WeakPolarHBondContact CD1-OG 3.29Å; I41-V350 HydrophobicContact CB-CG2 4.03Å; I41-V350 HydrophobicContact CG1-CB 4.42Å; I41-V350 HydrophobicContact CG1-CG2 3.64Å; I41-V350 HydrophobicContact CG2-CG2 3.75Å
42E94.5Very high89.7Confident11 Ų1113.1 Ų13.15%0.0516%0.06CC..Hα-helixtrans-55.5-42.2-180-171.7-172.8-174.700112.7F38 R39 F40 P46 Q70 V73 S74 P102F38-E42 VanDerWaalsContact O-CB 3.29Å; F38-E42 WeakPolarHBondContact O-CB 3.38Å; F38-E42 PolarHBondContact O-N 3.21Å; R39-E42 WeakPolarHBondContact CD-OE2 3.48Å; R39-E42 IonicContact CZ-OE2 2.73Å; R39-E42 IonicContact NE-OE2 2.7Å; R39-E42 IonicContact NH1-OE1 2.99Å; R39-E42 IonicContact NH1-OE2 3.33Å; R39-E42 PolarHBondContact NH1-OE2 3.47Å; F40-E42 VanDerWaalsContact C-N 3.32Å; F40-E42 PolarHBondContact O-N 2.94Å; E42-P46 WeakPolarHBondContact O-CD 3.31Å; E42-Q70 HydrophobicContact CG-CG 4.39Å; E42-V73 HydrophobicContact CB-CG1 3.76Å; E42-V73 HydrophobicContact CG-CG1 4.19Å; E42-S74 WeakPolarHBondContact OE1-CB 3.46Å; E42-S74 PolarHBondContact OE1-OG 2.95Å; E42-P102 HydrophobicContact CB-CB 3.97Å; E42-P102 HydrophobicContact CG-CB 3.74Å; E42-P102 HydrophobicContact CG-CG 4.4Å
43G91.1Very high89.4Confident2 Ų216.6 Ų16.62%0.0219%0.085CC..Hα-helixtrans-82.4-25.3-179.800000114.6R39 F40 I41 Y103 E104R39-G43 PolarHBondContact O-N 3.17Å; R39-G43 VanDerWaalsContact O-N 3.1Å; F40-G43 PolarHBondContact O-N 3.07Å; I41-G43 VanDerWaalsContact C-N 3.31Å; I41-G43 PolarHBondContact O-N 3.03Å; G43-Y103 CarbonylContact C-O 3.58Å; G43-Y103 WeakPolarHBondContact CA-O 3.46Å; G43-E104 WeakPolarHBondContact O-CG 3.03Å
44Q90.2Very high89.2Confident9 Ų922.3 Ų22.34%0.04212%0.115CC..Hα-helixtrans-78.1-36.4178.4-65.9-56.9-61.400112.9F40 I41 A47 I48 Y103 Y105 V350F40-Q44 HydrophobicContact CD1-CG 4.38Å; F40-Q44 HydrophobicContact CD2-CG 3.99Å; F40-Q44 HydrophobicContact CE1-CG 4.05Å; F40-Q44 HydrophobicContact CE2-CG 3.58Å; F40-Q44 HydrophobicContact CG-CG 4.37Å; F40-Q44 HydrophobicContact CZ-CG 3.64Å; F40-Q44 VanDerWaalsContact O-CG 3.25Å; F40-Q44 WeakPolarHBondContact O-CG 3.29Å; F40-Q44 PolarHBondContact O-N 2.92Å; I41-Q44 PolarHBondContact O-N 3.46Å; Q44-A47 VanDerWaalsContact O-CB 3.23Å; Q44-A47 WeakPolarHBondContact O-CB 3.33Å; Q44-A47 PolarHBondContact O-N 3.48Å; Q44-I48 HydrophobicContact CB-CD1 4.33Å; Q44-I48 VanDerWaalsContact O-CG1 3.31Å; Q44-I48 WeakPolarHBondContact O-CG1 3.14Å; Q44-I48 PolarHBondContact O-N 3.43Å; Q44-I48 VanDerWaalsContact O-N 3.11Å; Q44-Y103 PolarHBondContact NE2-O 2.64Å; Q44-Y105 PolarHBondContact OE1-O 3.3Å; Q44-V350 HydrophobicContact CB-CG1 3.51Å; Q44-V350 HydrophobicContact CG-CG1 4.02Å
45L94.3Very high88.3Confident0 Ų025.5 Ų25.50%013%0.131CC..Hα-helixtrans-59.5-43.7-173-70.9168.9000114.6I41 A47 I48 A49 L66 V69 Q70 V73I41-L45 HydrophobicContact CG2-CD1 3.68Å; I41-L45 HydrophobicContact CG2-CG 4.24Å; I41-L45 VanDerWaalsContact O-CG 3.25Å; I41-L45 WeakPolarHBondContact O-CG 3.41Å; I41-L45 PolarHBondContact O-N 3.48Å; I41-L45 VanDerWaalsContact O-N 3.14Å; L45-A47 PolarHBondContact O-N 3.34Å; L45-I48 PolarHBondContact O-N 2.9Å; L45-A49 WeakPolarHBondContact O-CB 3.01Å; L45-A49 PolarHBondContact O-N 2.81Å; L45-L66 HydrophobicContact CD2-CB 4.47Å; L45-L66 HydrophobicContact CD2-CD2 3.73Å; L45-V69 HydrophobicContact CD1-CB 4.04Å; L45-V69 HydrophobicContact CD1-CG1 3.65Å; L45-Q70 HydrophobicContact CB-CB 4.04Å; L45-Q70 HydrophobicContact CB-CG 4.44Å; L45-Q70 HydrophobicContact CD1-CB 4.09Å; L45-V73 HydrophobicContact CD1-CG1 4.32Å
46P91.5Very high86.8Confident35 Ų3537.8 Ų37.823%0.22718%0.178CC..Hα-helixtrans-60-36.8176.8-25.836.2000112.7E42 A49 Y50 Q70E42-P46 WeakPolarHBondContact O-CD 3.31Å; P46-A49 WeakPolarHBondContact O-CB 3.12Å; P46-A49 PolarHBondContact O-N 2.85Å; P46-Y50 WeakPolarHBondContact O-CB 3.36Å; P46-Y50 PolarHBondContact O-N 3.4Å; P46-Q70 HydrophobicContact CG-CG 3.93Å
47A87.6Confident85.5Confident6 Ų646.8 Ų46.85%0.0522%0.22CC..Hα-helixtrans-65.8-46.6177.400000112.6Q44 L45 A49 Y50 E51 Y106Q44-A47 VanDerWaalsContact O-CB 3.23Å; Q44-A47 WeakPolarHBondContact O-CB 3.33Å; Q44-A47 PolarHBondContact O-N 3.48Å; L45-A47 PolarHBondContact O-N 3.34Å; A47-A49 PolarHBondContact O-N 3.18Å; A47-Y50 PolarHBondContact O-N 3.48Å; A47-E51 WeakPolarHBondContact O-CB 3.48Å; A47-E51 WeakPolarHBondContact O-CG 3.45Å; A47-E51 PolarHBondContact O-N 2.64Å; A47-Y106 HydrophobicContact CB-CD1 4.02Å; A47-Y106 HydrophobicContact CB-CE1 2.98Å; A47-Y106 HydrophobicContact CB-CE2 4.46Å; A47-Y106 WeakPolarHBondContact CB-OH 3.37Å
48I90.7Very high83.9Confident0 Ų048.1 Ų48.10%023%0.234CC..Hα-helixtrans-63.6-41178.9-58.7162.8000108.3Q44 L45 Y50 E51 S52 L66 V350 I353 R354 A357Q44-I48 HydrophobicContact CB-CD1 4.33Å; Q44-I48 VanDerWaalsContact O-CG1 3.31Å; Q44-I48 WeakPolarHBondContact O-CG1 3.14Å; Q44-I48 PolarHBondContact O-N 3.43Å; Q44-I48 VanDerWaalsContact O-N 3.11Å; L45-I48 PolarHBondContact O-N 2.9Å; I48-Y50 VanDerWaalsContact C-N 3.35Å; I48-Y50 PolarHBondContact O-N 3.13Å; I48-E51 PolarHBondContact O-N 3.26Å; I48-S52 WeakPolarHBondContact O-CB 3.41Å; I48-S52 PolarHBondContact O-N 2.76Å; I48-S52 PolarHBondContact O-OG 3.34Å; I48-L66 HydrophobicContact CB-CD1 4.02Å; I48-L66 HydrophobicContact CG2-CD1 3.62Å; I48-V350 HydrophobicContact CD1-CG1 4.08Å; I48-I353 HydrophobicContact CD1-CG2 4.27Å; I48-I353 HydrophobicContact CG2-CG2 4.28Å; I48-R354 HydrophobicContact CD1-CB 3.66Å; I48-R354 HydrophobicContact CD1-CG 4.37Å; I48-R354 HydrophobicContact CG1-CB 3.71Å; I48-R354 HydrophobicContact CG1-CG 3.88Å; I48-A357 HydrophobicContact CG2-CB 3.78Å
49A90.1Very high82.5Confident2 Ų250.4 Ų50.42%0.01726%0.257CS..Hα-helixtrans-60.9-42.1174.600000112.3L45 P46 A47 S52 S53 P63 L66L45-A49 WeakPolarHBondContact O-CB 3.01Å; L45-A49 PolarHBondContact O-N 2.81Å; P46-A49 WeakPolarHBondContact O-CB 3.12Å; P46-A49 PolarHBondContact O-N 2.85Å; A47-A49 PolarHBondContact O-N 3.18Å; A49-S52 WeakPolarHBondContact CA-OG 3.37Å; A49-S52 PolarHBondContact O-OG 2.03Å; A49-S53 WeakPolarHBondContact O-CB 3.47Å; A49-S53 PolarHBondContact O-N 2.95Å; A49-S53 VanDerWaalsContact O-N 3.15Å; A49-P63 HydrophobicContact CB-CB 4.12Å; A49-L66 HydrophobicContact CB-CB 4.09Å; A49-L66 HydrophobicContact CB-CD1 4.22Å
50Y89Confident81.4Confident159 Ų15958.1 Ų58.162%0.62430%0.299SS*.Hα-helixtrans-66.1-51.2176.6177.4-98.9000111.7P46 A47 I48 S52 S53 L54P46-Y50 WeakPolarHBondContact O-CB 3.36Å; P46-Y50 PolarHBondContact O-N 3.4Å; A47-Y50 PolarHBondContact O-N 3.48Å; I48-Y50 VanDerWaalsContact C-N 3.35Å; I48-Y50 PolarHBondContact O-N 3.13Å; Y50-S52 PolarHBondContact O-N 2.67Å; Y50-S53 WeakPolarHBondContact O-CB 3.48Å; Y50-S53 PolarHBondContact O-N 3.16Å; Y50-S53 PolarHBondContact O-OG 3.32Å; Y50-L54 HydrophobicContact CE1-CD1 4.32Å
51E84.8Confident81.4Confident36 Ų3659.9 Ų59.917%0.16832%0.319CS..Hα-helixtrans-65.7-41.3-178.5-67.8171.4-166.700112A47 I48 S53 L54 R354 M358A47-E51 WeakPolarHBondContact O-CB 3.48Å; A47-E51 WeakPolarHBondContact O-CG 3.45Å; A47-E51 PolarHBondContact O-N 2.64Å; I48-E51 PolarHBondContact O-N 3.26Å; E51-S53 VanDerWaalsContact C-N 3.27Å; E51-S53 PolarHBondContact O-N 3.27Å; E51-L54 WeakPolarHBondContact O-CB 3.33Å; E51-L54 PolarHBondContact O-N 3.23Å; E51-L54 VanDerWaalsContact O-N 3.12Å; E51-R354 IonicContact OE1-CZ 3.97Å; E51-R354 IonicContact OE1-NH1 3.07Å; E51-R354 PolarHBondContact OE1-NH1 3.4Å; E51-R354 IonicContact OE1-NH2 2.92Å; E51-R354 PolarHBondContact OE1-NH2 3.2Å; E51-R354 IonicContact OE2-CZ 3.1Å; E51-R354 IonicContact OE2-NE 2.84Å; E51-R354 IonicContact OE2-NH1 3.85Å; E51-R354 PolarHBondContact OE2-NH1 2.64Å; E51-R354 IonicContact OE2-NH2 3.3Å; E51-R354 PolarHBondContact OE2-NH2 3.37Å; E51-M358 HydrophobicContact CB-CE 3.9Å; E51-M358 HydrophobicContact CB-SD 3.56Å; E51-M358 VanDerWaalsContact CB-SD 3.56Å
52S83.4Confident81.2Confident1 Ų160.6 Ų60.61%0.00732%0.323CS..Hα-helixtrans-67.2-27176.360.80000113.2I48 A49 Y50 L54 L55I48-S52 WeakPolarHBondContact O-CB 3.41Å; I48-S52 PolarHBondContact O-N 2.76Å; I48-S52 PolarHBondContact O-OG 3.34Å; A49-S52 WeakPolarHBondContact CA-OG 3.37Å; A49-S52 PolarHBondContact O-OG 2.03Å; Y50-S52 PolarHBondContact O-N 2.67Å; S52-L54 PolarHBondContact O-N 3.28Å; S52-L55 WeakPolarHBondContact O-CB 3.44Å; S52-L55 PolarHBondContact O-N 2.85Å
53S80.3Confident81Confident73 Ų7361 Ų6151%0.5133%0.326SS..Hα-helixtrans-66.2-20.1173.877.10000113.3A49 Y50 E51 L55A49-S53 WeakPolarHBondContact O-CB 3.47Å; A49-S53 PolarHBondContact O-N 2.95Å; A49-S53 VanDerWaalsContact O-N 3.15Å; Y50-S53 WeakPolarHBondContact O-CB 3.48Å; Y50-S53 PolarHBondContact O-N 3.16Å; Y50-S53 PolarHBondContact O-OG 3.32Å; E51-S53 VanDerWaalsContact C-N 3.27Å; E51-S53 PolarHBondContact O-N 3.27Å; S53-L55 VanDerWaalsContact C-N 3.33Å
54L77.1Confident81Confident121 Ų12169.1 Ų69.163%0.63436%0.356SS*.THydrogen-bonded Turntrans-82.1-14.5174.7-58.5173.9000112.3Y50 E51 S52Y50-L54 HydrophobicContact CE1-CD1 4.32Å; E51-L54 WeakPolarHBondContact O-CB 3.33Å; E51-L54 PolarHBondContact O-N 3.23Å; E51-L54 VanDerWaalsContact O-N 3.12Å; S52-L54 PolarHBondContact O-N 3.28Å
55L70.6Confident81.2Confident67 Ų6772.3 Ų72.335%0.35137%0.371SS..SBendtrans-88.3119.6-179.8-61.2173.6000109.5S52 S53 E57 G58 A357 M358S52-L55 WeakPolarHBondContact O-CB 3.44Å; S52-L55 PolarHBondContact O-N 2.85Å; S53-L55 VanDerWaalsContact C-N 3.33Å; L55-E57 PolarHBondContact O-N 3.27Å; L55-G58 PolarHBondContact O-N 2.99Å; L55-G58 VanDerWaalsContact O-N 3.09Å; L55-A357 WeakPolarHBondContact CD1-O 3.39Å; L55-M358 HydrophobicContact CD1-CE 4.48Å; L55-M358 HydrophobicContact CD1-SD 3.8Å
56R60.6Low81.2Confident258 Ų25872.3 Ų72.397%0.97437%0.371SS*.THydrogen-bonded Turntrans-51.7-29.4-179.4-89.9-178.3155.9-167.9-5.6113.8
57E60.2Low81.3Confident190 Ų19078.2 Ų78.289%0.88839%0.389SS*.THydrogen-bonded Turntrans-91.1-11.2-174.2-66.1-178.817200114.1L55 G59L55-E57 PolarHBondContact O-N 3.27Å; E57-G59 PolarHBondContact O-N 3.37Å
58G57.1Low81.8Confident28 Ų2882.4 Ų82.429%0.28941%0.407SS..SBendtrans-66-15.9-169.200000115.7L55 L62L55-G58 PolarHBondContact O-N 2.99Å; L55-G58 VanDerWaalsContact O-N 3.09Å; G58-L62 WeakPolarHBondContact O-CB 3.44Å
59G63.5Low82.1Confident48 Ų4882.7 Ų82.750%0.49541%0.409SS..THydrogen-bonded Turntrans62.3144.2-172.300000112.2E57 G61 L62E57-G59 PolarHBondContact O-N 3.37Å; G59-G61 PolarHBondContact O-N 2.94Å; G59-L62 PolarHBondContact O-N 3.02Å
60N70.9Confident82.4Confident166 Ų16685.3 Ų85.389%0.88842%0.421SS*.THydrogen-bonded Turntrans-61.1-10.3-179.9-65.5-20.5000113.7
61G87.1Confident82.8Confident45 Ų4580.2 Ų80.246%0.46441%0.412SS..Hα-helixtrans-79-36.9-178.700000114.9G59 R64 Q65G59-G61 PolarHBondContact O-N 2.94Å; G61-R64 PolarHBondContact O-N 3.01Å; G61-Q65 PolarHBondContact O-N 3.41Å
62L90.1Very high83.3Confident16 Ų1683.4 Ų83.48%0.08443%0.43CS..Hα-helixtrans-64.1-48.5-172.5175.467.9000112.6L9 I13 G58 G59 R64 Q65 L66 A357L9-L62 HydrophobicContact CD2-CD1 3.93Å; L9-L62 HydrophobicContact CD2-CD2 3.7Å; L9-L62 HydrophobicContact CD2-CG 4.46Å; L9-L62 HydrophobicContact CG-CD1 4.38Å; I13-L62 HydrophobicContact CD1-CD1 3.58Å; G58-L62 WeakPolarHBondContact O-CB 3.44Å; G59-L62 PolarHBondContact O-N 3.02Å; L62-R64 PolarHBondContact O-N 3.44Å; L62-Q65 PolarHBondContact O-N 3.35Å; L62-Q65 VanDerWaalsContact O-N 3.16Å; L62-L66 HydrophobicContact CD1-CD1 3.97Å; L62-L66 HydrophobicContact CD1-CD2 4.25Å; L62-L66 HydrophobicContact CD1-CG 3.89Å; L62-L66 HydrophobicContact CG-CD1 3.95Å; L62-L66 HydrophobicContact CG-CG 4.28Å; L62-L66 WeakPolarHBondContact O-CG 3.48Å; L62-L66 PolarHBondContact O-N 3.2Å; L62-A357 HydrophobicContact CD2-CB 4.16Å
63P90.7Very high84Confident18 Ų1883.3 Ų83.312%0.11743%0.43CS..Hα-helixtrans-59-36.4177.5-26.136000113.1A49 R67A49-P63 HydrophobicContact CB-CB 4.12Å; P63-R67 VanDerWaalsContact O-CG 3.29Å; P63-R67 WeakPolarHBondContact O-CG 3.27Å; P63-R67 PolarHBondContact O-N 2.58Å; P63-R67 VanDerWaalsContact O-N 3.13Å
64R91.5Very high84.8Confident173 Ų17381.1 Ų81.165%0.65341%0.414SS*.Hα-helixtrans-65.5-49.1175.5178.8179.7174.5163.83111G61 L62 L66 R67 E68G61-R64 PolarHBondContact O-N 3.01Å; L62-R64 PolarHBondContact O-N 3.44Å; R64-L66 VanDerWaalsContact C-N 3.33Å; R64-L66 PolarHBondContact O-N 2.88Å; R64-R67 PolarHBondContact O-N 3.26Å; R64-E68 WeakPolarHBondContact CG-OE1 3.26Å; R64-E68 IonicContact CZ-OE1 3.27Å; R64-E68 IonicContact NE-OE1 3.14Å; R64-E68 PolarHBondContact NE-OE1 3.3Å; R64-E68 IonicContact NH2-OE1 3.9Å; R64-E68 WeakPolarHBondContact O-CG 3.5Å; R64-E68 PolarHBondContact O-N 3.45Å
65Q93.6Very high85.7Confident76 Ų7680.1 Ų80.136%0.35541%0.413SS..Hα-helixtrans-58.9-44.7178.7-171.7178.416.700111.5I13 G61 L62 R67 E68 V69I13-Q65 HydrophobicContact CG2-CG 4.24Å; G61-Q65 PolarHBondContact O-N 3.41Å; L62-Q65 PolarHBondContact O-N 3.35Å; L62-Q65 VanDerWaalsContact O-N 3.16Å; Q65-R67 VanDerWaalsContact C-N 3.32Å; Q65-R67 PolarHBondContact O-N 2.67Å; Q65-E68 PolarHBondContact O-N 2.95Å; Q65-V69 WeakPolarHBondContact O-CG2 3.41Å; Q65-V69 PolarHBondContact O-N 3.28Å
66L95Very high87Confident1 Ų177.4 Ų77.41%0.00540%0.399CS..Hα-helixtrans-64.7-34.7178.5-65.5175.8000112.6I13 L45 I48 A49 L62 R64 V69 Q70 I353I13-L66 HydrophobicContact CD1-CD2 4.14Å; I13-L66 HydrophobicContact CG1-CD2 4.38Å; L45-L66 HydrophobicContact CD2-CB 4.47Å; L45-L66 HydrophobicContact CD2-CD2 3.73Å; I48-L66 HydrophobicContact CB-CD1 4.02Å; I48-L66 HydrophobicContact CG2-CD1 3.62Å; A49-L66 HydrophobicContact CB-CB 4.09Å; A49-L66 HydrophobicContact CB-CD1 4.22Å; L62-L66 HydrophobicContact CD1-CD1 3.97Å; L62-L66 HydrophobicContact CD1-CD2 4.25Å; L62-L66 HydrophobicContact CD1-CG 3.89Å; L62-L66 HydrophobicContact CG-CD1 3.95Å; L62-L66 HydrophobicContact CG-CG 4.28Å; L62-L66 WeakPolarHBondContact O-CG 3.48Å; L62-L66 PolarHBondContact O-N 3.2Å; R64-L66 VanDerWaalsContact C-N 3.33Å; R64-L66 PolarHBondContact O-N 2.88Å; L66-V69 PolarHBondContact O-N 2.8Å; L66-Q70 WeakPolarHBondContact O-CB 3.13Å; L66-Q70 PolarHBondContact O-N 3.1Å; L66-I353 HydrophobicContact CD2-CG2 3.83Å
67R94.2Very high88.7Confident158 Ų15865.1 Ų65.160%0.59635%0.352SS*.Hα-helixtrans-68.6-37.1173-73177-170.6177.64.1112.7P63 R64 Q65 Q70 A71P63-R67 VanDerWaalsContact O-CG 3.29Å; P63-R67 WeakPolarHBondContact O-CG 3.27Å; P63-R67 PolarHBondContact O-N 2.58Å; P63-R67 VanDerWaalsContact O-N 3.13Å; R64-R67 PolarHBondContact O-N 3.26Å; Q65-R67 VanDerWaalsContact C-N 3.32Å; Q65-R67 PolarHBondContact O-N 2.67Å; R67-Q70 WeakPolarHBondContact O-CB 3.23Å; R67-Q70 PolarHBondContact O-N 2.73Å; R67-A71 PolarHBondContact O-N 3.04Å
68E96.1Very high90.4Very high94 Ų9459.9 Ų59.944%0.43933%0.331SS..Hα-helixtrans-64.2-43.3173.9-70.7169.9-171.700110.6R64 Q65 Q70 A71 N72R64-E68 WeakPolarHBondContact CG-OE1 3.26Å; R64-E68 IonicContact CZ-OE1 3.27Å; R64-E68 IonicContact NE-OE1 3.14Å; R64-E68 PolarHBondContact NE-OE1 3.3Å; R64-E68 IonicContact NH2-OE1 3.9Å; R64-E68 WeakPolarHBondContact O-CG 3.5Å; R64-E68 PolarHBondContact O-N 3.45Å; Q65-E68 PolarHBondContact O-N 2.95Å; E68-Q70 VanDerWaalsContact C-N 3.34Å; E68-Q70 PolarHBondContact O-N 3.37Å; E68-A71 PolarHBondContact O-N 3.41Å; E68-N72 PolarHBondContact O-N 3.21Å; E68-N72 VanDerWaalsContact O-N 3.12Å
69V97.3Very high92.2Very high7 Ų761 Ų614%0.04234%0.337CS..Hα-helixtrans-63-40.3173.3-179.20000111.4I13 L16 L20 L45 Q65 L66 N72 V73I13-V69 HydrophobicContact CG2-CG2 4.28Å; L16-V69 HydrophobicContact CD2-CG1 4.1Å; L20-V69 HydrophobicContact CD1-CG1 3.77Å; L45-V69 HydrophobicContact CD1-CB 4.04Å; L45-V69 HydrophobicContact CD1-CG1 3.65Å; Q65-V69 WeakPolarHBondContact O-CG2 3.41Å; Q65-V69 PolarHBondContact O-N 3.28Å; L66-V69 PolarHBondContact O-N 2.8Å; V69-N72 PolarHBondContact O-N 3.26Å; V69-V73 WeakPolarHBondContact O-CG1 3Å; V69-V73 PolarHBondContact O-N 3.43Å
70Q96.8Very high93.7Very high57 Ų5758.7 Ų58.727%0.26631%0.314SS..Hα-helixtrans-60.2-45.5176.3-174.8-137.5-13.100111.8E42 L45 P46 L66 R67 E68 N72 V73 S74E42-Q70 HydrophobicContact CG-CG 4.39Å; L45-Q70 HydrophobicContact CB-CB 4.04Å; L45-Q70 HydrophobicContact CB-CG 4.44Å; L45-Q70 HydrophobicContact CD1-CB 4.09Å; P46-Q70 HydrophobicContact CG-CG 3.93Å; L66-Q70 WeakPolarHBondContact O-CB 3.13Å; L66-Q70 PolarHBondContact O-N 3.1Å; R67-Q70 WeakPolarHBondContact O-CB 3.23Å; R67-Q70 PolarHBondContact O-N 2.73Å; E68-Q70 VanDerWaalsContact C-N 3.34Å; E68-Q70 PolarHBondContact O-N 3.37Å; Q70-N72 VanDerWaalsContact C-N 3.33Å; Q70-N72 PolarHBondContact O-N 2.88Å; Q70-V73 WeakPolarHBondContact O-CG1 3.3Å; Q70-V73 PolarHBondContact O-N 3.13Å; Q70-S74 WeakPolarHBondContact O-CB 3.21Å; Q70-S74 PolarHBondContact O-N 2.81Å
71A97.1Very high94.9Very high51 Ų5152.6 Ų52.642%0.42128%0.281SS..Hα-helixtrans-60.4-45.117700000111.1R67 E68 S74 T75R67-A71 PolarHBondContact O-N 3.04Å; E68-A71 PolarHBondContact O-N 3.41Å; A71-S74 WeakPolarHBondContact O-CB 3.42Å; A71-S74 PolarHBondContact O-N 3.46Å; A71-T75 PolarHBondContact O-N 3.07Å; A71-T75 PolarHBondContact O-OG1 3.44Å
72N96.8Very high95.3Very high103 Ų10354.2 Ų54.255%0.55128%0.283SS*.Hα-helixtrans-62.3-45.8178.8-68.7-11.7000112.5E68 V69 Q70 S74 T75 L76E68-N72 PolarHBondContact O-N 3.21Å; E68-N72 VanDerWaalsContact O-N 3.12Å; V69-N72 PolarHBondContact O-N 3.26Å; Q70-N72 VanDerWaalsContact C-N 3.33Å; Q70-N72 PolarHBondContact O-N 2.88Å; N72-S74 VanDerWaalsContact C-N 3.31Å; N72-S74 PolarHBondContact O-N 3.46Å; N72-T75 PolarHBondContact O-N 3.12Å; N72-L76 PolarHBondContact O-N 2.99Å
73V96.9Very high95.5Very high0 Ų056 Ų560%029%0.291CS..Hα-helixtrans-67.8-32.3177.969.60000111.9L20 F38 I41 E42 L45 V69 Q70 L76 A77L20-V73 HydrophobicContact CD1-CB 4.15Å; L20-V73 HydrophobicContact CD2-CB 4.05Å; L20-V73 HydrophobicContact CD2-CG2 3.76Å; F38-V73 HydrophobicContact CB-CG2 3.78Å; F38-V73 HydrophobicContact CD1-CG2 4.42Å; F38-V73 HydrophobicContact CG-CG2 4.36Å; F38-V73 WeakPolarHBondContact O-CG2 3.42Å; I41-V73 HydrophobicContact CB-CG2 4.16Å; I41-V73 HydrophobicContact CG2-CB 4.27Å; I41-V73 HydrophobicContact CG2-CG1 4.09Å; I41-V73 HydrophobicContact CG2-CG2 3.99Å; E42-V73 HydrophobicContact CB-CG1 3.76Å; E42-V73 HydrophobicContact CG-CG1 4.19Å; L45-V73 HydrophobicContact CD1-CG1 4.32Å; V69-V73 WeakPolarHBondContact O-CG1 3Å; V69-V73 PolarHBondContact O-N 3.43Å; Q70-V73 WeakPolarHBondContact O-CG1 3.3Å; Q70-V73 PolarHBondContact O-N 3.13Å; V73-L76 PolarHBondContact O-N 2.93Å; V73-A77 VanDerWaalsContact O-CB 3.26Å; V73-A77 WeakPolarHBondContact O-CB 3.33Å; V73-A77 PolarHBondContact O-N 3.31Å
74S97.2Very high95.6Very high27 Ų2755.1 Ų55.119%0.18929%0.285CS..Hα-helixtrans-64.3-46.8174.8-167.40000111.1E42 Q70 A71 N72 L76 A77 N78E42-S74 WeakPolarHBondContact OE1-CB 3.46Å; E42-S74 PolarHBondContact OE1-OG 2.95Å; Q70-S74 WeakPolarHBondContact O-CB 3.21Å; Q70-S74 PolarHBondContact O-N 2.81Å; A71-S74 WeakPolarHBondContact O-CB 3.42Å; A71-S74 PolarHBondContact O-N 3.46Å; N72-S74 VanDerWaalsContact C-N 3.31Å; N72-S74 PolarHBondContact O-N 3.46Å; S74-L76 VanDerWaalsContact C-N 3.34Å; S74-L76 PolarHBondContact O-N 3.41Å; S74-A77 PolarHBondContact O-N 3.1Å; S74-N78 WeakPolarHBondContact O-CB 2.79Å; S74-N78 PolarHBondContact O-N 3.19Å; S74-N78 PolarHBondContact O-ND2 3.29Å
75T97.1Very high95.6Very high99 Ų9950 Ų5061%0.60727%0.27SS*.Hα-helixtrans-58.5-46174.2-62.20000111.4A71 N72 N78 A79A71-T75 PolarHBondContact O-N 3.07Å; A71-T75 PolarHBondContact O-OG1 3.44Å; N72-T75 PolarHBondContact O-N 3.12Å; T75-N78 PolarHBondContact O-N 3.24Å; T75-A79 WeakPolarHBondContact O-CB 3.44Å; T75-A79 PolarHBondContact O-N 2.83Å
76L96.9Very high95.7Very high10 Ų1053.7 Ų53.75%0.05229%0.287CS..Hα-helixtrans-61.4-48.6176.7176.159.9000112.3L20 C23 F38 N72 V73 S74 N78 A79 A80L20-L76 HydrophobicContact CB-CD2 4.5Å; L20-L76 HydrophobicContact CD2-CD2 3.91Å; C23-L76 HydrophobicContact CB-CD2 3.82Å; F38-L76 HydrophobicContact CD1-CD2 4.31Å; F38-L76 HydrophobicContact CD2-CD2 4.2Å; F38-L76 HydrophobicContact CD2-CG 4.11Å; F38-L76 HydrophobicContact CE1-CD2 4.07Å; F38-L76 HydrophobicContact CE2-CD2 3.93Å; F38-L76 HydrophobicContact CE2-CG 4Å; F38-L76 HydrophobicContact CG-CD2 4.41Å; F38-L76 HydrophobicContact CZ-CD2 3.89Å; F38-L76 HydrophobicContact CZ-CG 4.46Å; N72-L76 PolarHBondContact O-N 2.99Å; V73-L76 PolarHBondContact O-N 2.93Å; S74-L76 VanDerWaalsContact C-N 3.34Å; S74-L76 PolarHBondContact O-N 3.41Å; L76-N78 VanDerWaalsContact C-N 3.31Å; L76-N78 PolarHBondContact O-N 2.6Å; L76-A79 PolarHBondContact O-N 2.74Å; L76-A80 WeakPolarHBondContact O-CB 3.35Å; L76-A80 PolarHBondContact O-N 2.62Å
77A96.1Very high95.4Very high0 Ų058.1 Ų58.10%031%0.311CS..Hα-helixtrans-60.8-41.8-179.700000111.4L35 F38 V73 S74 A80 I81L35-A77 HydrophobicContact CD1-CB 3.93Å; L35-A77 WeakPolarHBondContact CD1-O 3.2Å; F38-A77 HydrophobicContact CB-CB 3.94Å; V73-A77 VanDerWaalsContact O-CB 3.26Å; V73-A77 WeakPolarHBondContact O-CB 3.33Å; V73-A77 PolarHBondContact O-N 3.31Å; S74-A77 PolarHBondContact O-N 3.1Å; A77-A80 PolarHBondContact O-N 3.12Å; A77-I81 PolarHBondContact O-N 3.47Å
78N96Very high95.1Very high80 Ų8052.2 Ų52.243%0.42829%0.292SS..Hα-helixtrans-67.6-41.4177.2-67.8-31.9000112.1R39 S74 T75 L76 A80 I81R39-N78 PolarHBondContact NH1-OD1 2.69Å; R39-N78 PolarHBondContact NH2-OD1 2.57Å; S74-N78 WeakPolarHBondContact O-CB 2.79Å; S74-N78 PolarHBondContact O-N 3.19Å; S74-N78 PolarHBondContact O-ND2 3.29Å; T75-N78 PolarHBondContact O-N 3.24Å; L76-N78 VanDerWaalsContact C-N 3.31Å; L76-N78 PolarHBondContact O-N 2.6Å; N78-A80 VanDerWaalsContact C-N 3.27Å; N78-A80 PolarHBondContact O-N 3.27Å; N78-I81 PolarHBondContact O-N 2.93Å
79A95.7Very high94.8Very high52 Ų5249.7 Ų49.743%0.4329%0.286SS..Hα-helixtrans-66.7-28.317600000112.9T75 L76 P82 H83T75-A79 WeakPolarHBondContact O-CB 3.44Å; T75-A79 PolarHBondContact O-N 2.83Å; L76-A79 PolarHBondContact O-N 2.74Å; A79-P82 WeakPolarHBondContact O-CD 3.32Å; A79-H83 PolarHBondContact O-CD2 3.07Å
80A95.2Very high94.3Very high0 Ų056.4 Ų56.40%032%0.315CS..Hα-helixtrans-77.4-22178.400000114.3V30 L35 L76 A77 N78 H83 V84V30-A80 HydrophobicContact CB-CB 4.16Å; V30-A80 HydrophobicContact CG1-CB 3.75Å; V30-A80 HydrophobicContact CG2-CB 4.43Å; L35-A80 HydrophobicContact CD1-CB 4.44Å; L76-A80 WeakPolarHBondContact O-CB 3.35Å; L76-A80 PolarHBondContact O-N 2.62Å; A77-A80 PolarHBondContact O-N 3.12Å; N78-A80 VanDerWaalsContact C-N 3.27Å; N78-A80 PolarHBondContact O-N 3.27Å; A80-H83 PolarHBondContact O-N 3.38Å; A80-H83 VanDerWaalsContact O-N 3.16Å; A80-V84 WeakPolarHBondContact O-CG2 3.01Å; A80-V84 PolarHBondContact O-N 3.5Å
81I95Very high93.5Very high38 Ų3854.6 Ų54.620%0.19531%0.308CS..Hα-helixtrans-54.1-49.9-176.2-75.4168.3000112.7L35 A77 N78 H83 V84 L85 F92L35-I81 HydrophobicContact CD1-CG1 4.46Å; L35-I81 HydrophobicContact CD2-CG1 4.02Å; A77-I81 PolarHBondContact O-N 3.47Å; N78-I81 PolarHBondContact O-N 2.93Å; I81-H83 VanDerWaalsContact C-N 3.31Å; I81-H83 PolarHBondContact O-N 3.24Å; I81-V84 PolarHBondContact O-N 2.83Å; I81-L85 HydrophobicContact CG2-CD1 3.81Å; I81-L85 HydrophobicContact CG2-CG 4.42Å; I81-L85 WeakPolarHBondContact O-CB 3.17Å; I81-L85 PolarHBondContact O-N 3.49Å; I81-F92 HydrophobicContact CG1-CE2 4.45Å; I81-F92 HydrophobicContact CG2-CE2 4.36Å; I81-F92 HydrophobicContact CG2-CZ 4.1Å
82P95.2Very high92.9Very high78 Ų7852.6 Ų52.651%0.50629%0.29SS..Hα-helixtrans-58.6-41.5179.2-25.335.4000112.8A79 L85 E86A79-P82 WeakPolarHBondContact O-CD 3.32Å; P82-L85 PolarHBondContact O-N 3.27Å; P82-E86 PolarHBondContact O-N 3.15Å
83H94.8Very high92.3Very high54 Ų5452.7 Ų52.725%0.2529%0.29CS..Hα-helixtrans-67.1-40.7178.8-59-55000112.3S27 A79 A80 I81 L85 E86 N87S27-H83 PolarHBondContact O-CD2 3.44Å; S27-H83 PolarHBondContact OG-NE2 3.48Å; A79-H83 PolarHBondContact O-CD2 3.07Å; A80-H83 PolarHBondContact O-N 3.38Å; A80-H83 VanDerWaalsContact O-N 3.16Å; I81-H83 VanDerWaalsContact C-N 3.31Å; I81-H83 PolarHBondContact O-N 3.24Å; H83-L85 VanDerWaalsContact C-N 3.34Å; H83-E86 PolarHBondContact O-N 3.2Å; H83-N87 WeakPolarHBondContact O-CB 3.14Å; H83-N87 PolarHBondContact O-N 2.66Å; H83-N87 PolarHBondContact O-ND2 2.92Å
84V92.3Very high91.4Very high0 Ų055 Ų550%030%0.3CS..Hα-helixtrans-66.9-38.1175.7174.90000111.2V30 S32 L35 A80 I81 E86 D88 F92V30-V84 HydrophobicContact CG1-CG2 4.01Å; V30-V84 WeakPolarHBondContact O-CG2 3.31Å; S32-V84 WeakPolarHBondContact OG-CG1 2.96Å; L35-V84 HydrophobicContact CB-CG2 4.07Å; L35-V84 HydrophobicContact CD2-CB 4.26Å; L35-V84 HydrophobicContact CD2-CG1 4.27Å; L35-V84 HydrophobicContact CD2-CG2 4.1Å; A80-V84 WeakPolarHBondContact O-CG2 3.01Å; A80-V84 PolarHBondContact O-N 3.5Å; I81-V84 PolarHBondContact O-N 2.83Å; V84-E86 VanDerWaalsContact C-N 3.3Å; V84-E86 PolarHBondContact O-N 2.82Å; V84-D88 CarbonylContact O-C 3.6Å; V84-D88 VanDerWaalsContact O-C 3.27Å; V84-D88 WeakPolarHBondContact O-CA 3.42Å; V84-D88 PolarHBondContact O-N 2.83Å; V84-F92 HydrophobicContact CG1-CB 4.21Å; V84-F92 HydrophobicContact CG1-CD2 3.77Å; V84-F92 HydrophobicContact CG1-CG 4.39Å
85L93.3Very high90.4Very high66 Ų6653.7 Ų53.735%0.34629%0.291SS..Hα-helixtrans-63.6-35.9173.9-83.6169.5000112.2I81 P82 H83 A89 F92I81-L85 HydrophobicContact CG2-CD1 3.81Å; I81-L85 HydrophobicContact CG2-CG 4.42Å; I81-L85 WeakPolarHBondContact O-CB 3.17Å; I81-L85 PolarHBondContact O-N 3.49Å; P82-L85 PolarHBondContact O-N 3.27Å; H83-L85 VanDerWaalsContact C-N 3.34Å; L85-A89 WeakPolarHBondContact O-CA 2.87Å; L85-A89 WeakPolarHBondContact O-CB 2.8Å; L85-A89 PolarHBondContact O-N 2.81Å; L85-F92 HydrophobicContact CD1-CE1 4.3Å; L85-F92 HydrophobicContact CD2-CB 4.35Å; L85-F92 HydrophobicContact CD2-CD1 3.22Å; L85-F92 HydrophobicContact CD2-CE1 3.57Å; L85-F92 HydrophobicContact CD2-CG 3.85Å; L85-F92 HydrophobicContact CD2-CZ 4.45Å; L85-F92 HydrophobicContact CG-CD1 3.89Å; L85-F92 HydrophobicContact CG-CE1 3.96Å; L85-F92 HydrophobicContact CG-CG 4.23Å; L85-F92 HydrophobicContact CG-CZ 4.37Å
86E94.3Very high89.8Confident152 Ų15253.3 Ų53.371%0.7128%0.281SS*.Hα-helixtrans-71.7-46.7176.5-174175.3-171.700111.8P82 H83 V84P82-E86 PolarHBondContact O-N 3.15Å; H83-E86 PolarHBondContact O-N 3.2Å; V84-E86 VanDerWaalsContact C-N 3.3Å; V84-E86 PolarHBondContact O-N 2.82Å
87N89.7Confident88.8Confident95 Ų9554.3 Ų54.351%0.50829%0.286SS..Hα-helixtrans-84.7-29-172.5-66.8-31.7000114S28 H83S28-N87 PolarHBondContact O-ND2 2.96Å; H83-N87 WeakPolarHBondContact O-CB 3.14Å; H83-N87 PolarHBondContact O-N 2.66Å; H83-N87 PolarHBondContact O-ND2 2.92Å
88D87.6Confident87.5Confident34 Ų3454.5 Ų54.518%0.18229%0.287CS..Hα-helixtrans-147.543.5-171.1-169.817000112.6S32 V84 K90 T91 F92S32-D88 VanDerWaalsContact CB-OD2 3.23Å; S32-D88 WeakPolarHBondContact CB-OD2 3.48Å; S32-D88 PolarHBondContact OG-OD2 3.42Å; V84-D88 CarbonylContact O-C 3.6Å; V84-D88 VanDerWaalsContact O-C 3.27Å; V84-D88 WeakPolarHBondContact O-CA 3.42Å; V84-D88 PolarHBondContact O-N 2.83Å; D88-K90 PolarHBondContact O-N 2.68Å; D88-K90 VanDerWaalsContact O-N 3.13Å; D88-T91 VanDerWaalsContact CG-CB 3.48Å; D88-T91 PolarHBondContact O-N 3.29Å; D88-T91 WeakPolarHBondContact OD1-CB 3.48Å; D88-T91 PolarHBondContact OD1-OG1 2.98Å; D88-T91 VanDerWaalsContact OD2-CB 3.25Å; D88-T91 WeakPolarHBondContact OD2-CB 3.37Å; D88-T91 PolarHBondContact OD2-OG1 3.46Å; D88-F92 WeakPolarHBondContact O-CB 3.15Å; D88-F92 PolarHBondContact O-N 2.97Å
89A89.2Confident86.8Confident40 Ų4050.7 Ų50.733%0.33127%0.266SS..Hα-helixtrans-49.5-42.1-179.300000113.1L85 F92 L93L85-A89 WeakPolarHBondContact O-CA 2.87Å; L85-A89 WeakPolarHBondContact O-CB 2.8Å; L85-A89 PolarHBondContact O-N 2.81Å; A89-F92 PolarHBondContact O-N 3.47Å; A89-L93 WeakPolarHBondContact O-CB 3.33Å; A89-L93 VanDerWaalsContact O-CG 3.22Å; A89-L93 WeakPolarHBondContact O-CG 3.44Å; A89-L93 PolarHBondContact O-N 3.28Å
90K87.3Confident86.1Confident149 Ų14950 Ų5065%0.64826%0.259SS*.Hα-helixtrans-64.4-45.2-173.9-176.6-178.2178.6-1770111.5D88 K94D88-K90 PolarHBondContact O-N 2.68Å; D88-K90 VanDerWaalsContact O-N 3.13Å; K90-K94 WeakPolarHBondContact O-CG 3.37Å
91T79.3Confident85.5Confident19 Ų1953.5 Ų53.512%0.11728%0.275CS..Hα-helixtrans-71.4-46.7177.3-49.80000109.1D88 L93 K94 V95D88-T91 VanDerWaalsContact CG-CB 3.48Å; D88-T91 PolarHBondContact O-N 3.29Å; D88-T91 WeakPolarHBondContact OD1-CB 3.48Å; D88-T91 PolarHBondContact OD1-OG1 2.98Å; D88-T91 VanDerWaalsContact OD2-CB 3.25Å; D88-T91 WeakPolarHBondContact OD2-CB 3.37Å; D88-T91 PolarHBondContact OD2-OG1 3.46Å; T91-L93 PolarHBondContact O-N 3.07Å; T91-K94 PolarHBondContact O-N 2.72Å; T91-K94 VanDerWaalsContact O-N 3.1Å; T91-V95 HydrophobicContact CG2-CG2 4.37Å; T91-V95 WeakPolarHBondContact O-CG2 3.31Å; T91-V95 PolarHBondContact O-N 3.45Å
92F84.4Confident85Confident8 Ų854.6 Ų54.64%0.03528%0.284CS..Hα-helixtrans-54.1-49.8-179.6-177.8-84000112.3L35 I81 V84 L85 D88 A89 K94 V95 K96 L99L35-F92 HydrophobicContact CD2-CD2 4.15Å; L35-F92 HydrophobicContact CD2-CE2 3.82Å; I81-F92 HydrophobicContact CG1-CE2 4.45Å; I81-F92 HydrophobicContact CG2-CE2 4.36Å; I81-F92 HydrophobicContact CG2-CZ 4.1Å; V84-F92 HydrophobicContact CG1-CB 4.21Å; V84-F92 HydrophobicContact CG1-CD2 3.77Å; V84-F92 HydrophobicContact CG1-CG 4.39Å; L85-F92 HydrophobicContact CD1-CE1 4.3Å; L85-F92 HydrophobicContact CD2-CB 4.35Å; L85-F92 HydrophobicContact CD2-CD1 3.22Å; L85-F92 HydrophobicContact CD2-CE1 3.57Å; L85-F92 HydrophobicContact CD2-CG 3.85Å; L85-F92 HydrophobicContact CD2-CZ 4.45Å; L85-F92 HydrophobicContact CG-CD1 3.89Å; L85-F92 HydrophobicContact CG-CE1 3.96Å; L85-F92 HydrophobicContact CG-CG 4.23Å; L85-F92 HydrophobicContact CG-CZ 4.37Å; D88-F92 WeakPolarHBondContact O-CB 3.15Å; D88-F92 PolarHBondContact O-N 2.97Å; A89-F92 PolarHBondContact O-N 3.47Å; F92-K94 VanDerWaalsContact C-N 3.29Å; F92-K94 PolarHBondContact O-N 3.47Å; F92-V95 CarbonylContact O-C 3.27Å; F92-V95 PolarHBondContact O-N 3.26Å; F92-V95 VanDerWaalsContact O-N 3.13Å; F92-K96 HydrophobicContact CE1-CB 4.27Å; F92-K96 HydrophobicContact CE1-CD 4.41Å; F92-K96 HydrophobicContact CE1-CG 3.84Å; F92-K96 HydrophobicContact CZ-CG 4.29Å; F92-K96 WeakPolarHBondContact O-CA 2.84Å; F92-K96 WeakPolarHBondContact O-CB 2.95Å; F92-K96 PolarHBondContact O-N 2.97Å; F92-L99 HydrophobicContact CB-CD1 4.25Å; F92-L99 HydrophobicContact CD2-CB 4.07Å; F92-L99 HydrophobicContact CD2-CD1 3.47Å; F92-L99 VanDerWaalsContact CD2-CD1 3.47Å; F92-L99 HydrophobicContact CD2-CG 4.43Å; F92-L99 HydrophobicContact CE2-CB 3.85Å; F92-L99 HydrophobicContact CE2-CD1 4.13Å; F92-L99 HydrophobicContact CG-CD1 4.13Å
93L85.5Confident84Confident106 Ų10651.1 Ų51.156%0.55526%0.261SS*.Hα-helixtrans-63.4-33.3-178.8-71.3172.9000112.8A89 T91 V95A89-L93 WeakPolarHBondContact O-CB 3.33Å; A89-L93 VanDerWaalsContact O-CG 3.22Å; A89-L93 WeakPolarHBondContact O-CG 3.44Å; A89-L93 PolarHBondContact O-N 3.28Å; T91-L93 PolarHBondContact O-N 3.07Å; L93-V95 VanDerWaalsContact C-N 3.3Å; L93-V95 PolarHBondContact O-N 3.38Å
94K78.5Confident83Confident48 Ų4853.2 Ų53.221%0.20927%0.271CS..Hα-helixtrans-70.5-27.1176.8-73.3-177.7176.9-161.10113.2K90 T91 F92 L142K90-K94 WeakPolarHBondContact O-CG 3.37Å; T91-K94 PolarHBondContact O-N 2.72Å; T91-K94 VanDerWaalsContact O-N 3.1Å; F92-K94 VanDerWaalsContact C-N 3.29Å; F92-K94 PolarHBondContact O-N 3.47Å; K94-L142 HydrophobicContact CD-CB 4.11Å; K94-L142 HydrophobicContact CD-CD1 4.33Å; K94-L142 HydrophobicContact CD-CD2 4.11Å; K94-L142 HydrophobicContact CD-CG 4.44Å
95V75.8Confident81.8Confident0 Ų054.5 Ų54.50%028%0.276CS..THydrogen-bonded Turntrans-12525.8-174.9-64.50000112.7T91 F92 L93 N97 F98 L99 L145 P195T91-V95 HydrophobicContact CG2-CG2 4.37Å; T91-V95 WeakPolarHBondContact O-CG2 3.31Å; T91-V95 PolarHBondContact O-N 3.45Å; F92-V95 CarbonylContact O-C 3.27Å; F92-V95 PolarHBondContact O-N 3.26Å; F92-V95 VanDerWaalsContact O-N 3.13Å; L93-V95 VanDerWaalsContact C-N 3.3Å; L93-V95 PolarHBondContact O-N 3.38Å; V95-N97 VanDerWaalsContact C-N 3.33Å; V95-N97 PolarHBondContact O-N 2.85Å; V95-F98 HydrophobicContact CB-CD2 3.87Å; V95-F98 HydrophobicContact CG1-CD2 4.2Å; V95-F98 WeakPolarHBondContact O-CA 3.47Å; V95-F98 WeakPolarHBondContact O-CB 3.36Å; V95-F98 PolarHBondContact O-N 3.23Å; V95-L99 HydrophobicContact CG2-CD1 3.62Å; V95-L99 HydrophobicContact CG2-CG 3.88Å; V95-L99 PolarHBondContact O-N 2.99Å; V95-L145 HydrophobicContact CG1-CB 4.37Å; V95-L145 HydrophobicContact CG1-CD1 3.81Å; V95-P195 HydrophobicContact CB-CB 4.16Å; V95-P195 HydrophobicContact CB-CG 3.97Å; V95-P195 HydrophobicContact CG1-CB 4.17Å; V95-P195 HydrophobicContact CG1-CG 3.99Å; V95-P195 HydrophobicContact CG2-CB 3.84Å; V95-P195 HydrophobicContact CG2-CG 4.19Å
96K84.2Confident80.5Confident91 Ų9155.4 Ų55.440%0.39628%0.276SS..Hα-helixtrans-56.3-44.7-170.7177.4-176.9174.1-170.90112.4F92 F98 L99 S100F92-K96 HydrophobicContact CE1-CB 4.27Å; F92-K96 HydrophobicContact CE1-CD 4.41Å; F92-K96 HydrophobicContact CE1-CG 3.84Å; F92-K96 HydrophobicContact CZ-CG 4.29Å; F92-K96 WeakPolarHBondContact O-CA 2.84Å; F92-K96 WeakPolarHBondContact O-CB 2.95Å; F92-K96 PolarHBondContact O-N 2.97Å; K96-F98 PolarHBondContact O-N 2.91Å; K96-L99 PolarHBondContact O-N 3.2Å; K96-S100 WeakPolarHBondContact O-CB 3.07Å; K96-S100 PolarHBondContact O-N 2.98Å; K96-S100 PolarHBondContact O-OG 3.21Å
97N76Confident79.2Confident30 Ų3049.3 Ų49.316%0.1625%0.249CC..Hα-helixtrans-68.1-23.5-178.9-70.7-28.4000112.8V95 S100 N149 M152 E153V95-N97 VanDerWaalsContact C-N 3.33Å; V95-N97 PolarHBondContact O-N 2.85Å; N97-S100 WeakPolarHBondContact CA-OG 3.45Å; N97-N149 WeakPolarHBondContact CB-OD1 3.08Å; N97-N149 PolarHBondContact N-OD1 3.47Å; N97-N149 PolarHBondContact ND2-O 3.32Å; N97-N149 PolarHBondContact ND2-OD1 3.27Å; N97-M152 HydrophobicContact CB-CB 4.45Å; N97-M152 HydrophobicContact CB-CE 3.43Å; N97-M152 VanDerWaalsContact CB-CE 3.43Å; N97-M152 HydrophobicContact CB-SD 4.26Å; N97-M152 WeakPolarHBondContact ND2-CB 3.46Å; N97-E153 WeakPolarHBondContact ND2-CG 3.32Å
98F69.3Low78.4Confident4 Ų451 Ų512%0.01826%0.258CS..Hα-helixtrans-71.2-65.5167-54.4-64.9000107.4V95 K96 S100 Q101 Y103 L145 M152 Y191 P195V95-F98 HydrophobicContact CB-CD2 3.87Å; V95-F98 HydrophobicContact CG1-CD2 4.2Å; V95-F98 WeakPolarHBondContact O-CA 3.47Å; V95-F98 WeakPolarHBondContact O-CB 3.36Å; V95-F98 PolarHBondContact O-N 3.23Å; K96-F98 PolarHBondContact O-N 2.91Å; F98-S100 PolarHBondContact O-N 3.05Å; F98-Q101 PolarHBondContact O-N 3.34Å; F98-Y103 HydrophobicContact CB-CE1 4.33Å; F98-Y103 WeakPolarHBondContact O-CE1 3.23Å; F98-Y103 PolarHBondContact O-OH 3.35Å; F98-L145 HydrophobicContact CE2-CD2 3.91Å; F98-L145 HydrophobicContact CZ-CD2 4.35Å; F98-M152 HydrophobicContact CD1-CE 4.29Å; F98-M152 HydrophobicContact CD2-CE 4.47Å; F98-M152 HydrophobicContact CE1-CE 3.59Å; F98-M152 HydrophobicContact CE1-SD 4.32Å; F98-M152 HydrophobicContact CE2-CE 3.87Å; F98-M152 HydrophobicContact CZ-CE 3.39Å; F98-Y191 WeakPolarHBondContact CD1-O 3.33Å; F98-Y191 HydrophobicContact CE1-CD2 4.19Å; F98-Y191 AromaticContact CE1-CG 3.83Å; F98-Y191 HydrophobicContact CE1-CG 3.83Å; F98-Y191 HydrophobicContact CZ-CG 4.35Å; F98-P195 HydrophobicContact CB-CG 4.21Å
99L81.1Confident77.9Confident0 Ų053.3 Ų53.30%026%0.264CS..Hα-helixtrans-61.9-16.4-171.3-60179.2000116.2S32 L35 L36 R39 F92 V95 K96 Y103S32-L99 WeakPolarHBondContact O-CD2 3.32Å; L35-L99 HydrophobicContact CD2-CB 3.96Å; L35-L99 HydrophobicContact CD2-CD1 4.47Å; L35-L99 HydrophobicContact CG-CB 4.36Å; L35-L99 HydrophobicContact CG-CD2 4.41Å; L36-L99 HydrophobicContact CB-CD2 3.65Å; L36-L99 HydrophobicContact CD1-CD2 4.16Å; L36-L99 HydrophobicContact CG-CD2 4.48Å; R39-L99 WeakPolarHBondContact CG-O 3.49Å; R39-L99 PolarHBondContact NE-O 3.06Å; R39-L99 VanDerWaalsContact NE-O 3.08Å; F92-L99 HydrophobicContact CB-CD1 4.25Å; F92-L99 HydrophobicContact CD2-CB 4.07Å; F92-L99 HydrophobicContact CD2-CD1 3.47Å; F92-L99 VanDerWaalsContact CD2-CD1 3.47Å; F92-L99 HydrophobicContact CD2-CG 4.43Å; F92-L99 HydrophobicContact CE2-CB 3.85Å; F92-L99 HydrophobicContact CE2-CD1 4.13Å; F92-L99 HydrophobicContact CG-CD1 4.13Å; V95-L99 HydrophobicContact CG2-CD1 3.62Å; V95-L99 HydrophobicContact CG2-CG 3.88Å; V95-L99 PolarHBondContact O-N 2.99Å; K96-L99 PolarHBondContact O-N 3.2Å; L99-Y103 PolarHBondContact N-OH 2.87Å
100S81.2Confident77.6Confident38 Ų3854.1 Ų54.127%0.26626%0.259SS..THydrogen-bonded Turntrans-87.5-13.8-177.956.50000115K96 N97 F98K96-S100 WeakPolarHBondContact O-CB 3.07Å; K96-S100 PolarHBondContact O-N 2.98Å; K96-S100 PolarHBondContact O-OG 3.21Å; N97-S100 WeakPolarHBondContact CA-OG 3.45Å; F98-S100 PolarHBondContact O-N 3.05Å
101Q80.8Confident77.6Confident73 Ų7349.6 Ų49.634%0.34125%0.246SC..SBendtrans-132.9146.3-173.4-63.4-175.15.200112.1R39 F98 Y103R39-Q101 WeakPolarHBondContact CB-O 3.38Å; F98-Q101 PolarHBondContact O-N 3.34Å; Q101-Y103 WeakPolarHBondContact O-CD1 3.36Å; Q101-Y103 WeakPolarHBondContact O-CE1 3.46Å
102P84.6Confident77.8Confident61 Ų6149.8 Ų49.840%0.39625%0.246SC..  trans-65.1153.6170.725.3-32.2000112.1R39 E42R39-P102 WeakPolarHBondContact O-CA 3.45Å; E42-P102 HydrophobicContact CB-CB 3.97Å; E42-P102 HydrophobicContact CG-CB 3.74Å; E42-P102 HydrophobicContact CG-CG 4.4Å
103Y74.3Confident77.7Confident6 Ų653.5 Ų53.52%0.02426%0.264CS..  trans-118.8121-177.6-33.7-68.9000114.3L36 R39 F40 G43 Q44 F98 L99 Q101 H192L36-Y103 HydrophobicContact CD1-CE2 3.53Å; L36-Y103 WeakPolarHBondContact CD1-OH 3.3Å; R39-Y103 HydrophobicContact CB-CD2 3.98Å; R39-Y103 HydrophobicContact CB-CE2 3.24Å; R39-Y103 HydrophobicContact CG-CE2 4.44Å; R39-Y103 PolarHBondContact O-N 3.15Å; R39-Y103 VanDerWaalsContact O-N 3.16Å; F40-Y103 HydrophobicContact CB-CD2 4.06Å; F40-Y103 HydrophobicContact CB-CE2 4.44Å; G43-Y103 CarbonylContact C-O 3.58Å; G43-Y103 WeakPolarHBondContact CA-O 3.46Å; Q44-Y103 PolarHBondContact NE2-O 2.64Å; F98-Y103 HydrophobicContact CB-CE1 4.33Å; F98-Y103 WeakPolarHBondContact O-CE1 3.23Å; F98-Y103 PolarHBondContact O-OH 3.35Å; L99-Y103 PolarHBondContact N-OH 2.87Å; Q101-Y103 WeakPolarHBondContact O-CD1 3.36Å; Q101-Y103 WeakPolarHBondContact O-CE1 3.46Å; Y103-H192 AromaticContact CD1-CE1 3.06Å; Y103-H192 WeakPolarHBondContact CD1-CE1 3.49Å; Y103-H192 AromaticContact CD1-CG 3.91Å; Y103-H192 AromaticContact CD1-ND1 3.02Å; Y103-H192 WeakPolarHBondContact CD1-ND1 3.43Å; Y103-H192 AromaticContact CD1-NE2 3.92Å; Y103-H192 HydrophobicContact CD2-CB 4.45Å; Y103-H192 AromaticContact CD2-ND1 3.88Å; Y103-H192 AromaticContact CE1-CE1 3.67Å; Y103-H192 AromaticContact CE1-ND1 3.43Å; Y103-H192 WeakPolarHBondContact CE1-ND1 2.94Å; Y103-H192 HydrophobicContact CG-CB 4.37Å; Y103-H192 AromaticContact CG-CE1 3.61Å; Y103-H192 AromaticContact CG-CG 3.67Å; Y103-H192 AromaticContact CG-ND1 3.25Å
104E73.8Confident77.2Confident98 Ų9851.7 Ų51.746%0.45826%0.264SS..  trans-99.6114176.4-73.4-164.2-154.900110.7G43 Y106 P189G43-E104 WeakPolarHBondContact O-CG 3.03Å; E104-Y106 HydrophobicContact CB-CE2 3.94Å; E104-Y106 WeakPolarHBondContact CB-OH 3.42Å; E104-Y106 VanDerWaalsContact CG-OH 3.24Å; E104-Y106 WeakPolarHBondContact CG-OH 3.42Å; E104-Y106 PolarHBondContact OE2-OH 2.95Å; E104-P189 HydrophobicContact CB-CB 4.31Å; E104-P189 WeakPolarHBondContact O-CB 3.27Å
105Y67Low77.1Confident26 Ų2653.3 Ų53.310%0.10228%0.281CS..  trans-138.8122.6-178.9-179-109.6000113.7Q44 P107 H297 F428 L432Q44-Y105 PolarHBondContact OE1-O 3.3Å; Y105-P107 VanDerWaalsContact CD1-CD 3.44Å; Y105-P107 HydrophobicContact CD1-CG 3.85Å; Y105-P107 HydrophobicContact CE1-CB 3.74Å; Y105-P107 VanDerWaalsContact CE1-CD 3.41Å; Y105-P107 HydrophobicContact CE1-CG 3.28Å; Y105-P107 HydrophobicContact CE2-CB 4.26Å; Y105-P107 WeakPolarHBondContact OH-CB 3.44Å; Y105-H297 AromaticContact CD1-CE1 2.95Å; Y105-H297 WeakPolarHBondContact CD1-CE1 3.39Å; Y105-H297 AromaticContact CD1-ND1 3.15Å; Y105-H297 WeakPolarHBondContact CD1-ND1 3.06Å; Y105-H297 AromaticContact CE1-CE1 3.48Å; Y105-H297 VanDerWaalsContact CE1-CE1 3.48Å; Y105-H297 WeakPolarHBondContact CE1-CE1 3.41Å; Y105-H297 AromaticContact CE1-ND1 3.32Å; Y105-H297 VanDerWaalsContact CE1-ND1 3.32Å; Y105-H297 WeakPolarHBondContact CE1-ND1 3.49Å; Y105-H297 VanDerWaalsContact CE1-O 3.27Å; Y105-H297 WeakPolarHBondContact CE1-O 3.11Å; Y105-H297 AromaticContact CG-CE1 3.62Å; Y105-F428 HydrophobicContact CE1-CE2 4.27Å; Y105-F428 HydrophobicContact CE1-CZ 4.19Å; Y105-L432 HydrophobicContact CD2-CD2 3.76Å; Y105-L432 HydrophobicContact CE1-CD2 4.19Å; Y105-L432 HydrophobicContact CE2-CD2 2.99Å; Y105-L432 HydrophobicContact CE2-CG 4.5Å; Y105-L432 VanDerWaalsContact OH-CD2 3.24Å; Y105-L432 WeakPolarHBondContact OH-CD2 3.14Å
106Y65.8Low77Confident86 Ų8655.9 Ų55.934%0.33729%0.292SS..  trans-132.881.6-170.7-41.3-55.9000112A47 E104 R354A47-Y106 HydrophobicContact CB-CD1 4.02Å; A47-Y106 HydrophobicContact CB-CE1 2.98Å; A47-Y106 HydrophobicContact CB-CE2 4.46Å; A47-Y106 WeakPolarHBondContact CB-OH 3.37Å; E104-Y106 HydrophobicContact CB-CE2 3.94Å; E104-Y106 WeakPolarHBondContact CB-OH 3.42Å; E104-Y106 VanDerWaalsContact CG-OH 3.24Å; E104-Y106 WeakPolarHBondContact CG-OH 3.42Å; E104-Y106 PolarHBondContact OE2-OH 2.95Å; Y106-R354 VanDerWaalsContact CD1-NH1 3.3Å
107P68.8Low76.3Confident24 Ų2454.8 Ų54.816%0.15629%0.286CS..PPolyproline II helixtrans-89.9144.8176.739-39000111.2Y105 R109 S299 R435Y105-P107 VanDerWaalsContact CD1-CD 3.44Å; Y105-P107 HydrophobicContact CD1-CG 3.85Å; Y105-P107 HydrophobicContact CE1-CB 3.74Å; Y105-P107 VanDerWaalsContact CE1-CD 3.41Å; Y105-P107 HydrophobicContact CE1-CG 3.28Å; Y105-P107 HydrophobicContact CE2-CB 4.26Å; Y105-P107 WeakPolarHBondContact OH-CB 3.44Å; P107-R109 PolarHBondContact O-N 3.21Å; P107-S299 WeakPolarHBondContact CB-OG 3.49Å; P107-S299 WeakPolarHBondContact CG-OG 3.15Å; P107-R435 VanDerWaalsContact CB-NH1 3.33Å
108N72.2Confident75.7Confident129 Ų12958.6 Ų58.669%0.6930%0.298SS*.PPolyproline II helixtrans-54.6130.8168.3-63.8-2.3000110.5S299N108-S299 WeakPolarHBondContact O-CB 3.38Å; N108-S299 PolarHBondContact O-OG 3.47Å
109R77.7Confident74.7Confident83 Ų8366.7 Ų66.731%0.31333%0.328SS..PPolyproline II helixtrans-55.1148.9176.4-66.9-111.9-174.2172.514111.5P107 S299 D360P107-R109 PolarHBondContact O-N 3.21Å; R109-S299 CarbonylContact C-O 3.43Å; R109-D360 WeakPolarHBondContact CD-OD2 3.3Å; R109-D360 IonicContact CZ-OD1 3.37Å; R109-D360 IonicContact CZ-OD2 3.08Å; R109-D360 IonicContact NE-OD1 3.45Å; R109-D360 IonicContact NE-OD2 2.98Å; R109-D360 PolarHBondContact NE-OD2 2.79Å; R109-D360 PolarHBondContact NH1-O 3.37Å; R109-D360 IonicContact NH1-OD1 3.3Å; R109-D360 IonicContact NH1-OD2 3.85Å; R109-D360 VanDerWaalsContact NH2-CB 3.27Å; R109-D360 VanDerWaalsContact NH2-CG 3.35Å; R109-D360 PolarHBondContact NH2-O 2.66Å; R109-D360 IonicContact NH2-OD2 3.82Å; R109-D360 PolarHBondContact NH2-OD2 3.47Å; R109-D360 VanDerWaalsContact NH2-OD2 3.13Å
110R82.3Confident72.8Confident57 Ų5771.5 Ų71.522%0.21535%0.352CS..BIsolated β-bridgetrans-137.7153.9-177-66.9179.9170.1-157.8-1.4109.1E257 R260 S299 F300 K301 R435R110-E257 IonicContact CZ-OE2 3.13Å; R110-E257 IonicContact NH1-OE2 3.82Å; R110-E257 PolarHBondContact NH1-OE2 2.93Å; R110-E257 IonicContact NH2-OE1 3.72Å; R110-E257 PolarHBondContact NH2-OE1 3.11Å; R110-E257 IonicContact NH2-OE2 2.64Å; R110-E257 PolarHBondContact NH2-OE2 2.61Å; R110-R260 VanDerWaalsContact CZ-CZ 3.46Å; R110-R260 VanDerWaalsContact NH1-NH2 3.15Å; R110-S299 PolarHBondContact N-O 3.12Å; R110-F300 HydrophobicContact CB-CD1 4.1Å; R110-F300 HydrophobicContact CB-CE1 4.04Å; R110-F300 HydrophobicContact CB-CZ 4.43Å; R110-F300 WeakPolarHBondContact O-CA 3.22Å; R110-K301 PolarHBondContact O-N 3.12Å; R110-R435 VanDerWaalsContact NE-NH2 3.13Å
111S87Confident70.7Confident55 Ų5574.4 Ų74.439%0.38536%0.363SS..  trans-106.6149.2166.2-89.10000111.1K301 E302S111-K301 VanDerWaalsContact OG-CE 3.24Å; S111-K301 WeakPolarHBondContact OG-CE 3.37Å; S111-E302 WeakPolarHBondContact CA-OE1 3.39Å; S111-E302 WeakPolarHBondContact CB-OE1 3.07Å; S111-E302 PolarHBondContact OG-OE1 3.07Å
112I83.9Confident68.5Low22 Ų2277.9 Ų77.911%0.11338%0.379CS..  trans-60.9147.6167.1-70.4175.6000109.1F268 Y269 F300 E302 F303I112-F268 HydrophobicContact CD1-CB 3.19Å; I112-F268 HydrophobicContact CD1-CD1 3.55Å; I112-F268 HydrophobicContact CD1-CD2 3.36Å; I112-F268 HydrophobicContact CD1-CE1 4.16Å; I112-F268 HydrophobicContact CD1-CE2 4Å; I112-F268 HydrophobicContact CD1-CG 3.07Å; I112-F268 HydrophobicContact CD1-CZ 4.32Å; I112-F268 HydrophobicContact CG1-CB 4.45Å; I112-F268 HydrophobicContact CG2-CD1 4.5Å; I112-Y269 HydrophobicContact CG2-CE2 4.45Å; I112-F300 HydrophobicContact CG1-CB 4.45Å; I112-F300 HydrophobicContact CG1-CD1 3.82Å; I112-F300 HydrophobicContact CG1-CG 4.49Å; I112-E302 HydrophobicContact CB-CG 4.4Å; I112-E302 HydrophobicContact CD1-CB 3.62Å; I112-E302 HydrophobicContact CD1-CG 4.02Å; I112-E302 HydrophobicContact CG1-CB 4.28Å; I112-E302 HydrophobicContact CG1-CG 4.27Å; I112-E302 VanDerWaalsContact N-CD 3.35Å; I112-E302 PolarHBondContact N-OE1 2.85Å; I112-E302 PolarHBondContact N-OE2 2.96Å; I112-F303 HydrophobicContact CD1-CD2 4.2Å; I112-F303 HydrophobicContact CD1-CE2 3.83Å; I112-F303 HydrophobicContact CG1-CE2 4.49Å
113Q81.1Confident66.4Low87 Ų8780.1 Ų80.141%0.40739%0.388SS..  trans-118.5110.9174.8-73.4-178.519.200109.3S115 K116 L261 S265Q113-S115 PolarHBondContact O-N 2.9Å; Q113-S115 VanDerWaalsContact O-N 3.14Å; Q113-K116 HydrophobicContact CB-CB 4.13Å; Q113-K116 HydrophobicContact CB-CG 3.88Å; Q113-K116 WeakPolarHBondContact O-CA 3.48Å; Q113-K116 WeakPolarHBondContact O-CB 3.43Å; Q113-K116 PolarHBondContact O-N 2.89Å; Q113-L261 HydrophobicContact CB-CD1 4.08Å; Q113-L261 HydrophobicContact CB-CG 4.41Å; Q113-L261 HydrophobicContact CG-CD1 3.94Å; Q113-L261 HydrophobicContact CG-CD2 4.28Å; Q113-L261 HydrophobicContact CG-CG 4.49Å; Q113-S265 PolarHBondContact N-OG 2.84Å; Q113-S265 PolarHBondContact O-OG 3.26Å
114A76Confident64.6Low67 Ų6787.5 Ų87.555%0.55442%0.423SS*.G310 helixtrans-54.8-32.5175.200000112.1K116 R117 Y269A114-K116 PolarHBondContact O-N 2.8Å; A114-R117 WeakPolarHBondContact O-CB 3.26Å; A114-R117 PolarHBondContact O-N 3.35Å; A114-R117 VanDerWaalsContact O-N 3.12Å; A114-Y269 WeakPolarHBondContact CB-OH 3.42Å
115S76.3Confident62.9Low82 Ų8288.5 Ų88.557%0.57343%0.431SS*.G310 helixtrans-65.6-18.9175.760.20000114.5Q113Q113-S115 PolarHBondContact O-N 2.9Å; Q113-S115 VanDerWaalsContact O-N 3.14Å
116K72.8Confident61.7Low54 Ų5490.6 Ų90.624%0.23544%0.443CS..G310 helixtrans-96.83.7176.6-65.8-67.3-169.3178.10112.9Q113 A114 E258 L261 N266Q113-K116 HydrophobicContact CB-CB 4.13Å; Q113-K116 HydrophobicContact CB-CG 3.88Å; Q113-K116 WeakPolarHBondContact O-CA 3.48Å; Q113-K116 WeakPolarHBondContact O-CB 3.43Å; Q113-K116 PolarHBondContact O-N 2.89Å; A114-K116 PolarHBondContact O-N 2.8Å; K116-E258 IonicContact NZ-OE1 2.82Å; K116-E258 PolarHBondContact NZ-OE1 3.16Å; K116-L261 HydrophobicContact CB-CG 4.33Å; K116-L261 HydrophobicContact CG-CD2 3.89Å; K116-L261 HydrophobicContact CG-CG 3.96Å; K116-N266 PolarHBondContact O-ND2 2.85Å
117R70.4Confident60.6Low68 Ų6893.2 Ų93.226%0.25746%0.463SS..SBendtrans-59.4143.2168.2-171.2175.2178.3-160.3-4.8109.3A114 R119 Y269A114-R117 WeakPolarHBondContact O-CB 3.26Å; A114-R117 PolarHBondContact O-N 3.35Å; A114-R117 VanDerWaalsContact O-N 3.12Å; R117-R119 PolarHBondContact O-N 3.43Å; R117-Y269 HydrophobicContact CB-CE2 4.36Å; R117-Y269 HydrophobicContact CG-CD2 4.12Å; R117-Y269 HydrophobicContact CG-CE2 4.33Å
118W63.1Low59.4Low110 Ų11095.4 Ų95.442%0.41748%0.483SS..  trans-57.6106.3168.4-65-22.3000108.1M120 E262 N266 F420W118-M120 PolarHBondContact O-N 3.46Å; W118-E262 PolarHBondContact NE1-OE1 2.84Å; W118-N266 WeakPolarHBondContact CB-OD1 3.25Å; W118-N266 HydrophobicContact CD2-CB 4.2Å; W118-N266 HydrophobicContact CE3-CB 4.42Å; W118-N266 VanDerWaalsContact CG-CG 3.46Å; W118-N266 VanDerWaalsContact CG-OD1 3.27Å; W118-N266 PolarHBondContact N-ND2 3.37Å; W118-N266 PolarHBondContact N-OD1 3.46Å; W118-N266 PolarHBondContact NE1-ND2 2.93Å; W118-F420 HydrophobicContact CH2-CD2 4.07Å; W118-F420 AromaticContact CH2-CE2 3.16Å; W118-F420 HydrophobicContact CH2-CE2 3.16Å; W118-F420 AromaticContact CH2-CZ 3.72Å; W118-F420 HydrophobicContact CH2-CZ 3.72Å; W118-F420 HydrophobicContact CZ2-CE2 4.08Å; W118-F420 HydrophobicContact CZ2-CZ 4.22Å; W118-F420 AromaticContact CZ3-CE2 3.6Å; W118-F420 HydrophobicContact CZ3-CE2 3.6Å; W118-F420 HydrophobicContact CZ3-CZ 4.3Å
119R48.9Very low58.1Low174 Ų17496.4 Ų96.466%0.65748%0.481SS*.  trans-69.1120.8152.6-59.1-174.6-162.4-177.44.1103.4R117 I121 Y376R117-R119 PolarHBondContact O-N 3.43Å; R119-I121 PolarHBondContact O-N 3.05Å; R119-Y376 PolarHBondContact NH1-OH 2.06Å
120M40.3Very low56.6Low102 Ų10297.6 Ų97.650%0.50250%0.5SS..  trans-26.7109.9179.4-90.1-176.8-81.300110.4W118 H122 Q398W118-M120 PolarHBondContact O-N 3.46Å; M120-H122 PolarHBondContact O-N 2.9Å; M120-Q398 PolarHBondContact SD-NE2 3.45Å
121I38Very low55Low98 Ų98100.7 Ų100.750%0.50353%0.53SS..  trans-68.4123.7171.6-57.4175.5000104.6R119 L125R119-I121 PolarHBondContact O-N 3.05Å; I121-L125 HydrophobicContact CG2-CB 4.18Å; I121-L125 HydrophobicContact CG2-CD1 3.37Å; I121-L125 HydrophobicContact CG2-CG 4.33Å
122H33.5Very low53.1Low146 Ų146100.5 Ų100.568%0.67653%0.527SS*.  trans-40.1142.9-179.6-77.2-68.8000111.2M120 E124 L125M120-H122 PolarHBondContact O-N 2.9Å; H122-E124 HydrophobicContact CB-CG 4.33Å; H122-E124 PolarHBondContact O-N 3.31Å; H122-L125 PolarHBondContact O-N 2.91Å; H122-L125 VanDerWaalsContact O-N 3.17Å
123N40.6Very low51.7Low109 Ų109103.5 Ų103.558%0.58354%0.543SS*.G310 helixtrans-43.6-21.8-179.5-69.4-23.3000114.5L125 L126N123-L125 PolarHBondContact O-N 3.44Å; N123-L125 VanDerWaalsContact O-N 3.12Å; N123-L126 WeakPolarHBondContact O-CB 3.5Å; N123-L126 PolarHBondContact O-N 2.88Å
124E37.1Very low50.2Low160 Ų160100.2 Ų100.275%0.74853%0.533SS*.G310 helixtrans-49.2-31.6174.7-60.5176.5175.700115.1H122H122-E124 HydrophobicContact CB-CG 4.33Å; H122-E124 PolarHBondContact O-N 3.31Å
125L37.6Very low49.3Very low119 Ų119100.6 Ų100.662%0.62353%0.531SS*.G310 helixtrans-84.9-15.6176.9-99.8158000113.9I121 H122 N123I121-L125 HydrophobicContact CG2-CB 4.18Å; I121-L125 HydrophobicContact CG2-CD1 3.37Å; I121-L125 HydrophobicContact CG2-CG 4.33Å; H122-L125 PolarHBondContact O-N 2.91Å; H122-L125 VanDerWaalsContact O-N 3.17Å; N123-L125 PolarHBondContact O-N 3.44Å; N123-L125 VanDerWaalsContact O-N 3.12Å
126L43Very low48.2Very low70 Ų7099.3 Ų99.337%0.36652%0.52SS..THydrogen-bonded Turntrans-80.1-22.2178.4-62.8174.8000112.3N123 A128 M405N123-L126 WeakPolarHBondContact O-CB 3.5Å; N123-L126 PolarHBondContact O-N 2.88Å; L126-A128 VanDerWaalsContact C-N 3.3Å; L126-A128 PolarHBondContact O-N 3.22Å; L126-M405 HydrophobicContact CB-CE 3.57Å; L126-M405 HydrophobicContact CD1-CE 4.14Å; L126-M405 HydrophobicContact CD2-CE 3.46Å; L126-M405 VanDerWaalsContact CD2-CE 3.46Å; L126-M405 HydrophobicContact CG-CE 3.88Å
127D42.3Very low47Very low142 Ų14298.1 Ų98.176%0.75952%0.516SS*.SBendtrans-74.1-22.3-179.2-69.6-28.9000112.9K129D127-K129 PolarHBondContact O-N 3.13Å
128A42.6Very low46.1Very low69 Ų6996.3 Ų96.357%0.5751%0.513SS*.SBendtrans-85.795.8175.300000110.2L126 P130L126-A128 VanDerWaalsContact C-N 3.3Å; L126-A128 PolarHBondContact O-N 3.22Å; A128-P130 WeakPolarHBondContact O-CD 3.48Å
129K45.8Very low46.1Very low151 Ų15193.9 Ų93.966%0.65751%0.512SS*.  trans-50.9126.2166.6-79.9-176.5-176.9-178.90109D127 S131 V407D127-K129 PolarHBondContact O-N 3.13Å; K129-S131 PolarHBondContact O-N 3.1Å; K129-V407 HydrophobicContact CD-CG2 4.4Å
130P45.6Very low46.5Very low108 Ų10893 Ų9370%0.70151%0.509SS*.  trans-58.7117.4170.520.9-28.1000108.1A128 T132A128-P130 WeakPolarHBondContact O-CD 3.48Å; P130-T132 PolarHBondContact O-N 2.83Å
131S48.5Very low47Very low122 Ų12288.5 Ų88.585%0.85349%0.487SS*.  trans-74-5-174.460.40000113.6K129K129-S131 PolarHBondContact O-N 3.1Å
132T47.1Very low48.1Very low50 Ų5084.9 Ų84.931%0.30747%0.468SS..SBendtrans-108.5122.7-170.4-18.70000109.4P130 V136 W419P130-T132 PolarHBondContact O-N 2.83Å; T132-V136 HydrophobicContact CG2-CB 4.22Å; T132-V136 HydrophobicContact CG2-CG1 3.81Å; T132-W419 WeakPolarHBondContact O-CH2 3.5Å; T132-W419 WeakPolarHBondContact O-CZ2 3.44Å
133D54.1Low49.7Very low85 Ų8582.4 Ų82.446%0.45546%0.46SS..  trans-72.4158.2174.49342.4000111.5S135 V136 L137D133-S135 VanDerWaalsContact C-N 3.33Å; D133-S135 PolarHBondContact O-N 2.96Å; D133-S135 WeakPolarHBondContact OD1-CA 3.42Å; D133-S135 WeakPolarHBondContact OD1-CB 3.26Å; D133-S135 PolarHBondContact OD1-N 2.86Å; D133-S135 PolarHBondContact OD1-OG 2.79Å; D133-S135 PolarHBondContact OD2-OG 3.26Å; D133-V136 PolarHBondContact O-N 3.3Å; D133-V136 PolarHBondContact OD1-N 2.93Å; D133-L137 PolarHBondContact O-N 3.28Å
134G49.6Very low50.7Low19 Ų1979.3 Ų79.320%0.19645%0.446CS..Hα-helixtrans-65.9-30.4-177.200000114.2T138 W419G134-T138 VanDerWaalsContact O-CB 3.28Å; G134-T138 WeakPolarHBondContact O-CB 3.39Å; G134-T138 PolarHBondContact O-N 3.33Å; G134-T138 PolarHBondContact O-OG1 2.85Å; G134-W419 VanDerWaalsContact CA-CZ2 3.44Å
135S58.6Low51.6Low74 Ų7471.9 Ų71.952%0.51741%0.412SS..Hα-helixtrans-69.2-37.6174.483.40000112.4D133 T138 S139D133-S135 VanDerWaalsContact C-N 3.33Å; D133-S135 PolarHBondContact O-N 2.96Å; D133-S135 WeakPolarHBondContact OD1-CA 3.42Å; D133-S135 WeakPolarHBondContact OD1-CB 3.26Å; D133-S135 PolarHBondContact OD1-N 2.86Å; D133-S135 PolarHBondContact OD1-OG 2.79Å; D133-S135 PolarHBondContact OD2-OG 3.26Å; S135-T138 PolarHBondContact O-N 3.34Å; S135-S139 VanDerWaalsContact O-CB 3.31Å; S135-S139 WeakPolarHBondContact O-CB 3.18Å; S135-S139 PolarHBondContact O-N 3.49Å; S135-S139 PolarHBondContact O-OG 3.43Å
136V53.2Low53Low55 Ų5568.3 Ų68.333%0.33340%0.397SS..Hα-helixtrans-64.2-46175173.10000109.8T132 D133 S139 R140T132-V136 HydrophobicContact CG2-CB 4.22Å; T132-V136 HydrophobicContact CG2-CG1 3.81Å; D133-V136 PolarHBondContact O-N 3.3Å; D133-V136 PolarHBondContact OD1-N 2.93Å; V136-S139 WeakPolarHBondContact O-CB 2.92Å; V136-S139 PolarHBondContact O-N 3.19Å; V136-R140 WeakPolarHBondContact O-CG 2.98Å; V136-R140 PolarHBondContact O-N 3.34Å
137L47.3Very low54.3Low30 Ų3068.3 Ų68.316%0.15740%0.395CS..Hα-helixtrans-67.5-44.6177.4-174.766.1000111.7D133 S139 R140 I141 W419 L422 L426D133-L137 PolarHBondContact O-N 3.28Å; L137-S139 PolarHBondContact O-N 2.97Å; L137-R140 HydrophobicContact CD1-CB 4.46Å; L137-R140 WeakPolarHBondContact O-CB 3.46Å; L137-R140 PolarHBondContact O-N 2.84Å; L137-I141 HydrophobicContact CD1-CD1 4.32Å; L137-I141 HydrophobicContact CD1-CG1 4.37Å; L137-I141 HydrophobicContact CD2-CD1 4.13Å; L137-I141 HydrophobicContact CG-CD1 3.83Å; L137-I141 HydrophobicContact CG-CG1 4.3Å; L137-I141 WeakPolarHBondContact O-CB 3.14Å; L137-I141 WeakPolarHBondContact O-CG1 2.93Å; L137-I141 PolarHBondContact O-N 2.75Å; L137-W419 HydrophobicContact CB-CH2 3.74Å; L137-W419 HydrophobicContact CB-CZ3 3.83Å; L137-W419 HydrophobicContact CD2-CE3 3.6Å; L137-W419 HydrophobicContact CD2-CH2 3.97Å; L137-W419 HydrophobicContact CD2-CZ3 3.13Å; L137-W419 HydrophobicContact CG-CH2 4.45Å; L137-W419 HydrophobicContact CG-CZ3 4.02Å; L137-L422 HydrophobicContact CD2-CD2 3.33Å; L137-L422 HydrophobicContact CD2-CG 4.15Å; L137-L422 HydrophobicContact CG-CD2 3.9Å; L137-L426 HydrophobicContact CD1-CD1 4.38Å; L137-L426 HydrophobicContact CD2-CD1 4.33Å
138T52.2Low55Low30 Ų3062.4 Ų62.418%0.18436%0.363CS..Hα-helixtrans-54.9-41.9175.6-58.70000110.5G134 S135 I141 L142 Y418G134-T138 VanDerWaalsContact O-CB 3.28Å; G134-T138 WeakPolarHBondContact O-CB 3.39Å; G134-T138 PolarHBondContact O-N 3.33Å; G134-T138 PolarHBondContact O-OG1 2.85Å; S135-T138 PolarHBondContact O-N 3.34Å; T138-I141 PolarHBondContact O-N 3.31Å; T138-L142 HydrophobicContact CG2-CD1 4.09Å; T138-L142 HydrophobicContact CG2-CG 4.43Å; T138-L142 WeakPolarHBondContact O-CB 3.14Å; T138-L142 VanDerWaalsContact O-CG 3.31Å; T138-L142 WeakPolarHBondContact O-CG 3.26Å; T138-L142 PolarHBondContact O-N 3.18Å; T138-Y418 PolarHBondContact OG1-OH 3.13Å
139S61.7Low55.9Low58 Ų5859.4 Ų59.441%0.40634%0.338SS..Hα-helixtrans-63.8-45.7174.5-60.80000112.3S135 V136 L137 I141 L142 N143S135-S139 VanDerWaalsContact O-CB 3.31Å; S135-S139 WeakPolarHBondContact O-CB 3.18Å; S135-S139 PolarHBondContact O-N 3.49Å; S135-S139 PolarHBondContact O-OG 3.43Å; V136-S139 WeakPolarHBondContact O-CB 2.92Å; V136-S139 PolarHBondContact O-N 3.19Å; L137-S139 PolarHBondContact O-N 2.97Å; S139-I141 VanDerWaalsContact C-N 3.29Å; S139-I141 PolarHBondContact O-N 3.31Å; S139-L142 PolarHBondContact O-N 2.87Å; S139-N143 WeakPolarHBondContact O-CB 3.48Å; S139-N143 PolarHBondContact O-N 3Å; S139-N143 PolarHBondContact O-ND2 2.81Å; S139-N143 PolarHBondContact O-OD1 3.17Å
140R57.4Low57Low156 Ų15655.1 Ų55.159%0.58932%0.317SS*.Hα-helixtrans-59.4-40.9175.7-74177.8179.6-170.90.3112.2V136 L137 N143 C144V136-R140 WeakPolarHBondContact O-CG 2.98Å; V136-R140 PolarHBondContact O-N 3.34Å; L137-R140 HydrophobicContact CD1-CB 4.46Å; L137-R140 WeakPolarHBondContact O-CB 3.46Å; L137-R140 PolarHBondContact O-N 2.84Å; R140-N143 PolarHBondContact O-N 3.04Å; R140-C144 WeakPolarHBondContact O-CB 2.74Å; R140-C144 PolarHBondContact O-N 2.75Å
141I51.9Low57.7Low8 Ų851.8 Ų51.84%0.04129%0.294CS..Hα-helixtrans-67.5-50.1178.5-75.1171.7000111L137 T138 S139 N143 C144 L145 L194 L422 L426L137-I141 HydrophobicContact CD1-CD1 4.32Å; L137-I141 HydrophobicContact CD1-CG1 4.37Å; L137-I141 HydrophobicContact CD2-CD1 4.13Å; L137-I141 HydrophobicContact CG-CD1 3.83Å; L137-I141 HydrophobicContact CG-CG1 4.3Å; L137-I141 WeakPolarHBondContact O-CB 3.14Å; L137-I141 WeakPolarHBondContact O-CG1 2.93Å; L137-I141 PolarHBondContact O-N 2.75Å; T138-I141 PolarHBondContact O-N 3.31Å; S139-I141 VanDerWaalsContact C-N 3.29Å; S139-I141 PolarHBondContact O-N 3.31Å; I141-N143 PolarHBondContact O-N 2.79Å; I141-C144 PolarHBondContact O-N 3.11Å; I141-C144 VanDerWaalsContact O-N 3.13Å; I141-L145 HydrophobicContact CG2-CD1 4.27Å; I141-L145 WeakPolarHBondContact O-CB 3.45Å; I141-L145 PolarHBondContact O-N 2.79Å; I141-L194 HydrophobicContact CG2-CD2 3.19Å; I141-L194 HydrophobicContact CG2-CG 4.39Å; I141-L422 HydrophobicContact CD1-CD1 3.28Å; I141-L422 HydrophobicContact CD1-CD2 3.57Å; I141-L422 HydrophobicContact CD1-CG 3.34Å; I141-L426 HydrophobicContact CD1-CD1 3.71Å; I141-L426 HydrophobicContact CD1-CD2 4.38Å; I141-L426 HydrophobicContact CD1-CG 3.83Å; I141-L426 HydrophobicContact CG1-CD1 4.05Å; I141-L426 HydrophobicContact CG1-CD2 4Å; I141-L426 HydrophobicContact CG1-CG 4.01Å
142L60.1Low58.1Low22 Ų2247.7 Ų47.712%0.11526%0.261CS..Hα-helixtrans-59.8-34.1176.2-76.5177.9000111.6K94 T138 S139 L145 S146 A198K94-L142 HydrophobicContact CD-CB 4.11Å; K94-L142 HydrophobicContact CD-CD1 4.33Å; K94-L142 HydrophobicContact CD-CD2 4.11Å; K94-L142 HydrophobicContact CD-CG 4.44Å; T138-L142 HydrophobicContact CG2-CD1 4.09Å; T138-L142 HydrophobicContact CG2-CG 4.43Å; T138-L142 WeakPolarHBondContact O-CB 3.14Å; T138-L142 VanDerWaalsContact O-CG 3.31Å; T138-L142 WeakPolarHBondContact O-CG 3.26Å; T138-L142 PolarHBondContact O-N 3.18Å; S139-L142 PolarHBondContact O-N 2.87Å; L142-L145 HydrophobicContact CD2-CD1 4.48Å; L142-S146 WeakPolarHBondContact O-CB 3.47Å; L142-S146 PolarHBondContact O-N 2.98Å; L142-A198 HydrophobicContact CD2-CB 3.97Å
143N66.9Low59Low93 Ų9349.4 Ų49.450%0.49727%0.266SS..Hα-helixtrans-68.8-46.3174-68.7-8.4000111.1S139 R140 I141 L145 S146 E147S139-N143 WeakPolarHBondContact O-CB 3.48Å; S139-N143 PolarHBondContact O-N 3Å; S139-N143 PolarHBondContact O-ND2 2.81Å; S139-N143 PolarHBondContact O-OD1 3.17Å; R140-N143 PolarHBondContact O-N 3.04Å; I141-N143 PolarHBondContact O-N 2.79Å; N143-L145 VanDerWaalsContact C-N 3.32Å; N143-L145 PolarHBondContact O-N 2.67Å; N143-S146 WeakPolarHBondContact O-CB 3.29Å; N143-S146 PolarHBondContact O-N 2.65Å; N143-E147 WeakPolarHBondContact O-CG 3Å; N143-E147 PolarHBondContact O-N 2.6Å
144C61.3Low59.4Low44 Ų4452.7 Ų52.730%0.29727%0.273SS..Hα-helixtrans-59.1-43.3175.5-174.30000111.9R140 I141 E147 L148R140-C144 WeakPolarHBondContact O-CB 2.74Å; R140-C144 PolarHBondContact O-N 2.75Å; I141-C144 PolarHBondContact O-N 3.11Å; I141-C144 VanDerWaalsContact O-N 3.13Å; C144-E147 PolarHBondContact O-N 2.58Å; C144-L148 PolarHBondContact O-N 3.16Å
145L57.8Low60Low4 Ų454.7 Ų54.72%0.02128%0.284CS..Hα-helixtrans-63.6-43.1174.3-78.9177.9000112.7V95 F98 I141 L142 N143 E147 L148 N149 L194V95-L145 HydrophobicContact CG1-CB 4.37Å; V95-L145 HydrophobicContact CG1-CD1 3.81Å; F98-L145 HydrophobicContact CE2-CD2 3.91Å; F98-L145 HydrophobicContact CZ-CD2 4.35Å; I141-L145 HydrophobicContact CG2-CD1 4.27Å; I141-L145 WeakPolarHBondContact O-CB 3.45Å; I141-L145 PolarHBondContact O-N 2.79Å; L142-L145 HydrophobicContact CD2-CD1 4.48Å; N143-L145 VanDerWaalsContact C-N 3.32Å; N143-L145 PolarHBondContact O-N 2.67Å; L145-E147 VanDerWaalsContact C-N 3.3Å; L145-E147 PolarHBondContact O-N 3.48Å; L145-L148 WeakPolarHBondContact O-CB 3.49Å; L145-L148 PolarHBondContact O-N 2.99Å; L145-N149 WeakPolarHBondContact O-CB 3.43Å; L145-N149 PolarHBondContact O-N 3.42Å; L145-L194 HydrophobicContact CD1-CB 4.14Å; L145-L194 HydrophobicContact CD1-CD2 3.38Å; L145-L194 HydrophobicContact CD1-CG 4.31Å; L145-L194 HydrophobicContact CD2-CB 4.19Å; L145-L194 HydrophobicContact CD2-CD2 3.73Å; L145-L194 HydrophobicContact CG-CD2 3.52Å
146S66.6Low60Low45 Ų4554.3 Ų54.332%0.31528%0.282SS..Hα-helixtrans-61.2-40.8176.7-174.70000111L142 N143 N149 R150L142-S146 WeakPolarHBondContact O-CB 3.47Å; L142-S146 PolarHBondContact O-N 2.98Å; N143-S146 WeakPolarHBondContact O-CB 3.29Å; N143-S146 PolarHBondContact O-N 2.65Å; S146-N149 WeakPolarHBondContact O-CB 3.36Å; S146-N149 PolarHBondContact O-N 3.25Å; S146-R150 WeakPolarHBondContact O-CB 3.41Å; S146-R150 PolarHBondContact O-N 2.9Å
147E69.2Low60.4Low69 Ų6954 Ų5432%0.32229%0.29SS..Hα-helixtrans-66.5-42.4175.3-71.4-53.1138.900112.1N143 C144 L145 N149 R150 L151N143-E147 WeakPolarHBondContact O-CG 3Å; N143-E147 PolarHBondContact O-N 2.6Å; C144-E147 PolarHBondContact O-N 2.58Å; L145-E147 VanDerWaalsContact C-N 3.3Å; L145-E147 PolarHBondContact O-N 3.48Å; E147-N149 VanDerWaalsContact C-N 3.32Å; E147-N149 PolarHBondContact O-N 3.13Å; E147-R150 PolarHBondContact O-N 3.45Å; E147-R150 IonicContact OE2-CZ 3.07Å; E147-R150 VanDerWaalsContact OE2-CZ 3.27Å; E147-R150 IonicContact OE2-NE 2.65Å; E147-R150 PolarHBondContact OE2-NE 3.44Å; E147-R150 IonicContact OE2-NH2 2.83Å; E147-R150 PolarHBondContact OE2-NH2 3.4Å; E147-L151 WeakPolarHBondContact O-CG 3.31Å; E147-L151 PolarHBondContact O-N 2.98Å
148L57Low60.7Low18 Ų1860.4 Ų60.49%0.09432%0.324CS..Hα-helixtrans-59.7-43.3171.7-85.7153.8000111.6C144 L145 L151 M152 Y191 V236C144-L148 PolarHBondContact O-N 3.16Å; L145-L148 WeakPolarHBondContact O-CB 3.49Å; L145-L148 PolarHBondContact O-N 2.99Å; L148-L151 PolarHBondContact O-N 3.19Å; L148-M152 WeakPolarHBondContact O-CG 2.96Å; L148-M152 PolarHBondContact O-N 2.97Å; L148-Y191 HydrophobicContact CD2-CE1 4.02Å; L148-V236 HydrophobicContact CD2-CG1 4.38Å
149N62.9Low60.8Low7 Ų764 Ų644%0.03734%0.342CS..Hα-helixtrans-60.7-48177-172.376.8000110.9N97 L145 S146 E147 L151 M152 E153N97-N149 WeakPolarHBondContact CB-OD1 3.08Å; N97-N149 PolarHBondContact N-OD1 3.47Å; N97-N149 PolarHBondContact ND2-O 3.32Å; N97-N149 PolarHBondContact ND2-OD1 3.27Å; L145-N149 WeakPolarHBondContact O-CB 3.43Å; L145-N149 PolarHBondContact O-N 3.42Å; S146-N149 WeakPolarHBondContact O-CB 3.36Å; S146-N149 PolarHBondContact O-N 3.25Å; E147-N149 VanDerWaalsContact C-N 3.32Å; E147-N149 PolarHBondContact O-N 3.13Å; N149-L151 VanDerWaalsContact C-N 3.31Å; N149-L151 PolarHBondContact O-N 3.18Å; N149-M152 WeakPolarHBondContact O-CB 3.23Å; N149-M152 PolarHBondContact O-N 3.2Å; N149-M152 VanDerWaalsContact O-N 3.12Å; N149-E153 PolarHBondContact ND2-OE1 2.87Å; N149-E153 VanDerWaalsContact ND2-OE1 3.16Å; N149-E153 PolarHBondContact O-N 3.32Å
150R67Low60.4Low60 Ų6065.3 Ų65.323%0.22635%0.351CS..Hα-helixtrans-56.7-43.7176.7-174.6172.572.1123.7-6.4111.8S146 E147 M152 E153 Y154 D232S146-R150 WeakPolarHBondContact O-CB 3.41Å; S146-R150 PolarHBondContact O-N 2.9Å; E147-R150 PolarHBondContact O-N 3.45Å; E147-R150 IonicContact OE2-CZ 3.07Å; E147-R150 VanDerWaalsContact OE2-CZ 3.27Å; E147-R150 IonicContact OE2-NE 2.65Å; E147-R150 PolarHBondContact OE2-NE 3.44Å; E147-R150 IonicContact OE2-NH2 2.83Å; E147-R150 PolarHBondContact OE2-NH2 3.4Å; R150-M152 PolarHBondContact O-N 2.9Å; R150-E153 PolarHBondContact O-N 3.14Å; R150-Y154 HydrophobicContact CG-CD2 4.08Å; R150-Y154 HydrophobicContact CG-CE2 3.71Å; R150-Y154 WeakPolarHBondContact O-CD2 3.37Å; R150-Y154 PolarHBondContact O-N 3.11Å; R150-Y154 VanDerWaalsContact O-N 3.12Å; R150-D232 VanDerWaalsContact CZ-CG 3.43Å; R150-D232 IonicContact CZ-OD1 2.61Å; R150-D232 IonicContact CZ-OD2 2.72Å; R150-D232 VanDerWaalsContact NH1-CG 3.31Å; R150-D232 IonicContact NH1-OD1 3.26Å; R150-D232 PolarHBondContact NH1-OD1 2.92Å; R150-D232 IonicContact NH1-OD2 2.72Å; R150-D232 PolarHBondContact NH1-OD2 3.12Å; R150-D232 IonicContact NH2-OD1 2.81Å; R150-D232 PolarHBondContact NH2-OD1 3.41Å; R150-D232 IonicContact NH2-OD2 3.9Å; R150-D232 PolarHBondContact NH2-OD2 2.88Å
151L60.4Low60.1Low39 Ų3962 Ų6220%0.20435%0.349CS..Hα-helixtrans-65.1-38.2176.3-73.8177.7000113.5E147 L148 N149 E153 Y154 S155 D232 V236E147-L151 WeakPolarHBondContact O-CG 3.31Å; E147-L151 PolarHBondContact O-N 2.98Å; L148-L151 PolarHBondContact O-N 3.19Å; N149-L151 VanDerWaalsContact C-N 3.31Å; N149-L151 PolarHBondContact O-N 3.18Å; L151-E153 VanDerWaalsContact C-N 3.34Å; L151-Y154 PolarHBondContact O-N 3.47Å; L151-S155 PolarHBondContact O-N 3.18Å; L151-D232 HydrophobicContact CD2-CB 3.93Å; L151-V236 HydrophobicContact CD1-CB 3.47Å; L151-V236 VanDerWaalsContact CD1-CB 3.47Å; L151-V236 HydrophobicContact CD1-CG1 4Å; L151-V236 HydrophobicContact CD1-CG2 3.19Å; L151-V236 HydrophobicContact CG-CG2 4.46Å
152M57.7Low60.1Low35 Ų3564.2 Ų64.217%0.17237%0.368CS..Hα-helixtrans-64.2-40.2175.5-72.9-169.2-6800111.4N97 F98 L148 N149 R150 Y154 S155 S156N97-M152 HydrophobicContact CB-CB 4.45Å; N97-M152 HydrophobicContact CB-CE 3.43Å; N97-M152 VanDerWaalsContact CB-CE 3.43Å; N97-M152 HydrophobicContact CB-SD 4.26Å; N97-M152 WeakPolarHBondContact ND2-CB 3.46Å; F98-M152 HydrophobicContact CD1-CE 4.29Å; F98-M152 HydrophobicContact CD2-CE 4.47Å; F98-M152 HydrophobicContact CE1-CE 3.59Å; F98-M152 HydrophobicContact CE1-SD 4.32Å; F98-M152 HydrophobicContact CE2-CE 3.87Å; F98-M152 HydrophobicContact CZ-CE 3.39Å; L148-M152 WeakPolarHBondContact O-CG 2.96Å; L148-M152 PolarHBondContact O-N 2.97Å; N149-M152 WeakPolarHBondContact O-CB 3.23Å; N149-M152 PolarHBondContact O-N 3.2Å; N149-M152 VanDerWaalsContact O-N 3.12Å; R150-M152 PolarHBondContact O-N 2.9Å; M152-Y154 PolarHBondContact O-N 3.25Å; M152-S155 PolarHBondContact O-N 3.3Å; M152-S155 PolarHBondContact O-OG 3.43Å; M152-S156 PolarHBondContact O-N 3.45Å; M152-S156 VanDerWaalsContact O-N 3.16Å; M152-S156 PolarHBondContact O-OG 3.33Å
153E65.2Low59.3Low86 Ų8671.4 Ų71.440%0.40239%0.393SS..Hα-helixtrans-59-46.2174.4-66.6179.7176.600111.1N97 N149 R150 L151 S155 S156 G157N97-E153 WeakPolarHBondContact ND2-CG 3.32Å; N149-E153 PolarHBondContact ND2-OE1 2.87Å; N149-E153 VanDerWaalsContact ND2-OE1 3.16Å; N149-E153 PolarHBondContact O-N 3.32Å; R150-E153 PolarHBondContact O-N 3.14Å; L151-E153 VanDerWaalsContact C-N 3.34Å; E153-S155 VanDerWaalsContact C-N 3.3Å; E153-S155 PolarHBondContact O-N 3.3Å; E153-S156 PolarHBondContact O-N 2.97Å; E153-S156 VanDerWaalsContact O-N 3.11Å; E153-S156 PolarHBondContact O-OG 2.96Å; E153-G157 PolarHBondContact O-N 3.41Å
154Y64.4Low58.1Low154 Ų15475.8 Ų75.860%0.60441%0.408SS*.Hα-helixtrans-60.3-37.1175.6-79.9-62.9000113.4R150 L151 M152 S156 G157R150-Y154 HydrophobicContact CG-CD2 4.08Å; R150-Y154 HydrophobicContact CG-CE2 3.71Å; R150-Y154 WeakPolarHBondContact O-CD2 3.37Å; R150-Y154 PolarHBondContact O-N 3.11Å; R150-Y154 VanDerWaalsContact O-N 3.12Å; L151-Y154 PolarHBondContact O-N 3.47Å; M152-Y154 PolarHBondContact O-N 3.25Å; Y154-S156 VanDerWaalsContact C-N 3.26Å; Y154-S156 PolarHBondContact O-N 3.17Å; Y154-G157 PolarHBondContact O-N 2.79Å
155S60.2Low57Low61 Ų6180.6 Ų80.643%0.42743%0.431SS..Hα-helixtrans-69.8-24.3178.375.80000113.5L151 M152 E153L151-S155 PolarHBondContact O-N 3.18Å; M152-S155 PolarHBondContact O-N 3.3Å; M152-S155 PolarHBondContact O-OG 3.43Å; E153-S155 VanDerWaalsContact C-N 3.3Å; E153-S155 PolarHBondContact O-N 3.3Å
156S59.1Low56.1Low67 Ų6783.6 Ų83.647%0.46945%0.449SS..Hα-helixtrans-89.6-14.9179.263.40000114.1M152 E153 Y154 D158M152-S156 PolarHBondContact O-N 3.45Å; M152-S156 VanDerWaalsContact O-N 3.16Å; M152-S156 PolarHBondContact O-OG 3.33Å; E153-S156 PolarHBondContact O-N 2.97Å; E153-S156 VanDerWaalsContact O-N 3.11Å; E153-S156 PolarHBondContact O-OG 2.96Å; Y154-S156 VanDerWaalsContact C-N 3.26Å; Y154-S156 PolarHBondContact O-N 3.17Å; S156-D158 PolarHBondContact O-N 2.95Å; S156-D158 VanDerWaalsContact O-N 3.1Å
157G61.3Low54.5Low49 Ų4986.8 Ų86.851%0.50546%0.463SS..  trans-65.7109.217300000109.7E153 Y154 D159E153-G157 PolarHBondContact O-N 3.41Å; Y154-G157 PolarHBondContact O-N 2.79Å; G157-D159 PolarHBondContact O-N 3.49Å
158D54.8Low52.8Low163 Ų16386.8 Ų86.887%0.87247%0.47SS*.  trans-69.824178.2-126-4.3000113S156 S160S156-D158 PolarHBondContact O-N 2.95Å; S156-D158 VanDerWaalsContact O-N 3.1Å; D158-S160 PolarHBondContact O-N 3.24Å
159D53Low51.5Low105 Ų10594.2 Ų94.256%0.56150%0.504SS*.  trans-7774.4-173.9-145.316.2000109.1G157 T161 A162G157-D159 PolarHBondContact O-N 3.49Å; D159-T161 PolarHBondContact O-N 3.43Å; D159-T161 VanDerWaalsContact O-N 3.11Å; D159-T161 PolarHBondContact OD1-OG1 3.46Å; D159-A162 HydrophobicContact CB-CB 4.27Å; D159-A162 WeakPolarHBondContact O-CB 3.25Å; D159-A162 PolarHBondContact O-N 3.16Å
160S54.7Low50.1Low86 Ų8697.3 Ų97.360%0.60154%0.538SS*.THydrogen-bonded Turntrans-55.9-22.1177.661.40000113D158 R163D158-S160 PolarHBondContact O-N 3.24Å; S160-R163 PolarHBondContact O-N 3.28Å
161T51.8Low48.3Very low88 Ų8898.7 Ų98.754%0.5455%0.548SS..THydrogen-bonded Turntrans-70.7-38172.946.80000112D159 R163 K164D159-T161 PolarHBondContact O-N 3.43Å; D159-T161 VanDerWaalsContact O-N 3.11Å; D159-T161 PolarHBondContact OD1-OG1 3.46Å; T161-R163 PolarHBondContact O-N 2.96Å; T161-K164 PolarHBondContact O-N 3Å; T161-K164 VanDerWaalsContact O-N 3.15Å
162A50.5Low46.8Very low54 Ų54102.6 Ų102.645%0.44658%0.579SS.*THydrogen-bonded Turntrans-67.7-16.3176.400000113.2D159D159-A162 HydrophobicContact CB-CB 4.27Å; D159-A162 WeakPolarHBondContact O-CB 3.25Å; D159-A162 PolarHBondContact O-N 3.16Å
163R42.7Very low45.5Very low172 Ų172104.8 Ų104.865%0.64960%0.603SS**THydrogen-bonded Turntrans-76.8-22.6173.2-82.5-176.1-179.5157.54.8114S160 T161S160-R163 PolarHBondContact O-N 3.28Å; T161-R163 PolarHBondContact O-N 2.96Å
164K43.7Very low43.9Very low185 Ų185106.9 Ų106.980%0.80462%0.621SS**THydrogen-bonded Turntrans-83.7-27.1-174.9-80.3-172.9176-179.50114.3T161 V166T161-K164 PolarHBondContact O-N 3Å; T161-K164 VanDerWaalsContact O-N 3.15Å; K164-V166 VanDerWaalsContact C-N 3.35Å
165D38.1Very low42.3Very low146 Ų146103.3 Ų103.378%0.78162%0.623SS**SBendtrans-94.712.6180-69.1-21000113.6D167D165-D167 PolarHBondContact O-N 2.72Å
166V38.2Very low41Very low67 Ų67103.3 Ų103.341%0.40662%0.622SS.*  trans-7786.4163.7-1750000106.5K164 C168K164-V166 VanDerWaalsContact C-N 3.35Å; V166-C168 VanDerWaalsContact C-N 3.26Å; V166-C168 PolarHBondContact O-N 3.13Å; V166-C168 PolarHBondContact O-SG 3.12Å; V166-C168 VanDerWaalsContact O-SG 3.39Å
167D33.2Very low39.8Very low111 Ų111103.5 Ų103.559%0.59462%0.623SS**  trans-62.889.4173.1-167.40.6000109.3D165 Q169D165-D167 PolarHBondContact O-N 2.72Å; D167-Q169 PolarHBondContact O-N 3.1Å; D167-Q169 VanDerWaalsContact O-N 3.11Å; D167-Q169 WeakPolarHBondContact OD1-CB 3.37Å; D167-Q169 WeakPolarHBondContact OD1-CG 3.24Å; D167-Q169 PolarHBondContact OD1-N 3.32Å
168C32.3Very low38.7Very low70 Ų70105.8 Ų105.847%0.47363%0.631SS.*G310 helixtrans-67.1-1.3-179.9-70.70000112.8V166 G170 I171V166-C168 VanDerWaalsContact C-N 3.26Å; V166-C168 PolarHBondContact O-N 3.13Å; V166-C168 PolarHBondContact O-SG 3.12Å; V166-C168 VanDerWaalsContact O-SG 3.39Å; C168-G170 PolarHBondContact O-N 3.16Å; C168-I171 PolarHBondContact O-N 2.97Å
169Q30.7Very low37.7Very low174 Ų174102.3 Ų102.381%0.81361%0.61SS**G310 helixtrans-67.3-18.6178.7-69.4-169.7-1.300113.3D167 I171D167-Q169 PolarHBondContact O-N 3.1Å; D167-Q169 VanDerWaalsContact O-N 3.11Å; D167-Q169 WeakPolarHBondContact OD1-CB 3.37Å; D167-Q169 WeakPolarHBondContact OD1-CG 3.24Å; D167-Q169 PolarHBondContact OD1-N 3.32Å; Q169-I171 VanDerWaalsContact C-N 3.27Å; Q169-I171 PolarHBondContact O-N 3.48Å
170G33Very low36.6Very low72 Ų72102.5 Ų102.574%0.74261%0.607SS**G310 helixtrans-77.6-6.3170.700000115C168C168-G170 PolarHBondContact O-N 3.16Å
171I29.4Very low35.4Very low88 Ų88101 Ų10145%0.45160%0.597SS.*  trans-111.767.7-177.2-47.8176.9000109.1C168 Q169C168-I171 PolarHBondContact O-N 2.97Å; Q169-I171 VanDerWaalsContact C-N 3.27Å; Q169-I171 PolarHBondContact O-N 3.48Å
172S29.1Very low34.4Very low122 Ų122105.5 Ų105.585%0.85360%0.604SS**  trans-84.8102.4145.373.90000104.7
173A31.3Very low33.4Very low80 Ų80105.1 Ų105.166%0.66159%0.592SS**SBendcis-146.7152.642.100000109.5
174V31.5Very low32.7Very low131 Ų131101 Ų10179%0.79458%0.583SS**  trans8073.8178-1600000113.3
175A30.8Very low32.1Very low78 Ų7896.3 Ų96.365%0.64557%0.573SS**PPolyproline II helixtrans-63.7126.8164.600000110.1
176P32.9Very low31.7Very low62 Ų6292.6 Ų92.640%0.40356%0.562SS.*PPolyproline II helixtrans-80.5129179.428.7-30.6000111.6E180P176-E180 HydrophobicContact CB-CB 4.26Å; P176-E180 HydrophobicContact CB-CG 3.94Å; P176-E180 WeakPolarHBondContact CB-OE1 3.27Å; P176-E180 WeakPolarHBondContact CB-OE2 3.48Å
177S33.2Very low31.2Very low71 Ų7190.4 Ų90.450%0.49755%0.548SS..PPolyproline II helixtrans-71.2161.5178.468.90000111.3E179 E180S177-E179 PolarHBondContact O-N 3.42Å; S177-E180 PolarHBondContact O-N 3.37Å
178S37.6Very low31.3Very low96 Ų9691.2 Ų91.267%0.67154%0.543SS*.THydrogen-bonded Turntrans-50.9-15.1177.567.50000115.4E180 C181S178-E180 VanDerWaalsContact C-N 3.34Å; S178-C181 PolarHBondContact O-N 2.97Å
179E33.7Very low31.3Very low91 Ų9190 Ų9043%0.42553%0.534SS..Hα-helixtrans-67.6-27.8172.7-77.5179.315500112.7S177 C181 R182 F183 K447S177-E179 PolarHBondContact O-N 3.42Å; E179-C181 VanDerWaalsContact C-N 3.32Å; E179-C181 PolarHBondContact O-N 2.91Å; E179-R182 CarbonylContact O-C 3.32Å; E179-R182 WeakPolarHBondContact O-CB 3.32Å; E179-R182 PolarHBondContact O-N 2.89Å; E179-R182 VanDerWaalsContact O-N 3.08Å; E179-F183 WeakPolarHBondContact O-CB 2.95Å; E179-F183 PolarHBondContact O-N 3Å; E179-K447 IonicContact OE1-NZ 3.88Å; E179-K447 PolarHBondContact OE1-NZ 2.72Å
180E30.8Very low31.2Very low108 Ų10882.1 Ų82.151%0.50550%0.499SS..Hα-helixtrans-69.9-26.2177.4-74.9-166-175.800113.6P176 S177 S178 F183 L184P176-E180 HydrophobicContact CB-CB 4.26Å; P176-E180 HydrophobicContact CB-CG 3.94Å; P176-E180 WeakPolarHBondContact CB-OE1 3.27Å; P176-E180 WeakPolarHBondContact CB-OE2 3.48Å; S177-E180 PolarHBondContact O-N 3.37Å; S178-E180 VanDerWaalsContact C-N 3.34Å; E180-F183 WeakPolarHBondContact O-CB 3.15Å; E180-F183 PolarHBondContact O-N 2.95Å; E180-L184 PolarHBondContact O-N 3.07Å
181C28.7Very low31.5Very low56 Ų5679.9 Ų79.938%0.37847%0.468SS..Hα-helixtrans-72.8-32.8170-780000111.7S178 E179S178-C181 PolarHBondContact O-N 2.97Å; E179-C181 VanDerWaalsContact C-N 3.32Å; E179-C181 PolarHBondContact O-N 2.91Å
182R30.5Very low32.4Very low181 Ų18176 Ų7668%0.68345%0.448SS*.Hα-helixtrans-71.4-34.4171.6-69.3-175-171.5174.82.8111.4E179 L184 S185 A186E179-R182 CarbonylContact O-C 3.32Å; E179-R182 WeakPolarHBondContact O-CB 3.32Å; E179-R182 PolarHBondContact O-N 2.89Å; E179-R182 VanDerWaalsContact O-N 3.08Å; R182-L184 VanDerWaalsContact C-N 3.32Å; R182-L184 PolarHBondContact O-N 3.31Å; R182-S185 PolarHBondContact O-N 3.29Å; R182-S185 VanDerWaalsContact O-N 3.11Å; R182-S185 PolarHBondContact O-OG 3.44Å; R182-A186 PolarHBondContact O-N 3.2Å
183F30.7Very low33Very low47 Ų4770.5 Ų70.521%0.20641%0.409CS..Hα-helixtrans-56.6-42.8175.3178.3-110.4000112.1E179 E180 S185 A186 I187 V436 R437 D440E179-F183 WeakPolarHBondContact O-CB 2.95Å; E179-F183 PolarHBondContact O-N 3Å; E180-F183 WeakPolarHBondContact O-CB 3.15Å; E180-F183 PolarHBondContact O-N 2.95Å; F183-S185 VanDerWaalsContact C-N 3.29Å; F183-S185 PolarHBondContact O-N 2.93Å; F183-A186 PolarHBondContact O-N 2.98Å; F183-A186 VanDerWaalsContact O-N 3.09Å; F183-I187 HydrophobicContact CD1-CD1 3.51Å; F183-I187 HydrophobicContact CD2-CD1 4.36Å; F183-I187 HydrophobicContact CE1-CD1 3.28Å; F183-I187 HydrophobicContact CE1-CG1 4.37Å; F183-I187 HydrophobicContact CE2-CD1 4.18Å; F183-I187 HydrophobicContact CE2-CG1 4.49Å; F183-I187 HydrophobicContact CG-CD1 4.04Å; F183-I187 HydrophobicContact CZ-CD1 3.65Å; F183-I187 HydrophobicContact CZ-CG1 4.32Å; F183-I187 WeakPolarHBondContact O-CD1 3.37Å; F183-I187 VanDerWaalsContact O-CG1 3.26Å; F183-I187 WeakPolarHBondContact O-CG1 3.46Å; F183-I187 PolarHBondContact O-N 3.43Å; F183-V436 HydrophobicContact CD2-CG1 3.95Å; F183-V436 HydrophobicContact CE2-CB 4.16Å; F183-V436 HydrophobicContact CE2-CG1 3.24Å; F183-V436 HydrophobicContact CZ-CB 4.28Å; F183-V436 HydrophobicContact CZ-CG1 3.71Å; F183-R437 HydrophobicContact CZ-CG 4.24Å; F183-D440 WeakPolarHBondContact CD2-OD2 3.47Å; F183-D440 WeakPolarHBondContact CE2-OD2 3.45Å
184L27.7Very low33.4Very low86 Ų8667 Ų6745%0.4538%0.379SS..Hα-helixtrans-62.9-32.3176.8-71.9171.3000113.4E180 R182 A186 I187E180-L184 PolarHBondContact O-N 3.07Å; R182-L184 VanDerWaalsContact C-N 3.32Å; R182-L184 PolarHBondContact O-N 3.31Å; L184-A186 VanDerWaalsContact C-N 3.33Å; L184-I187 HydrophobicContact CD2-CD1 4.3Å
185S31.8Very low33.7Very low85 Ų8560.8 Ų60.859%0.59434%0.342SS*.Hα-helixtrans-70.8-28.717573.30000113.2R182 F183R182-S185 PolarHBondContact O-N 3.29Å; R182-S185 VanDerWaalsContact O-N 3.11Å; R182-S185 PolarHBondContact O-OG 3.44Å; F183-S185 VanDerWaalsContact C-N 3.29Å; F183-S185 PolarHBondContact O-N 2.93Å
186A28.9Very low34.1Very low68 Ų6857.3 Ų57.356%0.56231%0.312SS*.Hα-helixtrans-81.9-12.1-179.800000114R182 F183 L184R182-A186 PolarHBondContact O-N 3.2Å; F183-A186 PolarHBondContact O-N 2.98Å; F183-A186 VanDerWaalsContact O-N 3.09Å; L184-A186 VanDerWaalsContact C-N 3.33Å
187I28.1Very low34.3Very low21 Ų2154.4 Ų54.411%0.10829%0.293CS..THydrogen-bonded Turntrans-88.8-14.8-176.1-66.8161.7000113.3F183 L184 P189 A190 Y191 V436F183-I187 HydrophobicContact CD1-CD1 3.51Å; F183-I187 HydrophobicContact CD2-CD1 4.36Å; F183-I187 HydrophobicContact CE1-CD1 3.28Å; F183-I187 HydrophobicContact CE1-CG1 4.37Å; F183-I187 HydrophobicContact CE2-CD1 4.18Å; F183-I187 HydrophobicContact CE2-CG1 4.49Å; F183-I187 HydrophobicContact CG-CD1 4.04Å; F183-I187 HydrophobicContact CZ-CD1 3.65Å; F183-I187 HydrophobicContact CZ-CG1 4.32Å; F183-I187 WeakPolarHBondContact O-CD1 3.37Å; F183-I187 VanDerWaalsContact O-CG1 3.26Å; F183-I187 WeakPolarHBondContact O-CG1 3.46Å; F183-I187 PolarHBondContact O-N 3.43Å; L184-I187 HydrophobicContact CD2-CD1 4.3Å; I187-P189 VanDerWaalsContact C-N 3.3Å; I187-P189 VanDerWaalsContact O-N 3.08Å; I187-A190 PolarHBondContact O-N 3.48Å; I187-Y191 HydrophobicContact CG2-CE2 3.8Å; I187-Y191 VanDerWaalsContact CG2-OH 3.29Å; I187-Y191 WeakPolarHBondContact CG2-OH 3.47Å; I187-Y191 WeakPolarHBondContact O-CE2 3.48Å; I187-V436 HydrophobicContact CB-CG1 4.44Å; I187-V436 HydrophobicContact CD1-CG1 4.05Å; I187-V436 HydrophobicContact CG1-CB 3.97Å; I187-V436 HydrophobicContact CG1-CG1 3.24Å; I187-V436 HydrophobicContact CG1-CG2 4.06Å
188R35.7Very low34.5Very low129 Ų12952.1 Ų52.149%0.48728%0.278SS..THydrogen-bonded Turntrans-44.7-40.2-176.6-117.6178.9-159.41685.8115.9A190R188-A190 PolarHBondContact O-N 2.81Å
189P32.1Very low34.5Very low44 Ų4448 Ų4829%0.28625%0.25SS..THydrogen-bonded Turntrans-92.325.6-168.7-9.128.6000116.3E104 I187 H192E104-P189 HydrophobicContact CB-CB 4.31Å; E104-P189 WeakPolarHBondContact O-CB 3.27Å; I187-P189 VanDerWaalsContact C-N 3.3Å; I187-P189 VanDerWaalsContact O-N 3.08Å; P189-H192 VanDerWaalsContact CA-NE2 3.29Å; P189-H192 WeakPolarHBondContact CA-NE2 3.42Å; P189-H192 PolarHBondContact O-CD2 2.71Å; P189-H192 PolarHBondContact O-NE2 2.9Å
190A28.3Very low34.7Very low9 Ų945.3 Ų45.37%0.07424%0.238CC..  trans-120.537.9-169.200000115.1I187 R188 H192 L432I187-A190 PolarHBondContact O-N 3.48Å; R188-A190 PolarHBondContact O-N 2.81Å; A190-H192 PolarHBondContact N-NE2 2.84Å; A190-L432 HydrophobicContact CB-CB 3.67Å; A190-L432 HydrophobicContact CB-CD2 3.92Å; A190-L432 HydrophobicContact CB-CG 4.25Å; A190-L432 WeakPolarHBondContact O-CB 3.4Å; A190-L432 WeakPolarHBondContact O-CD1 3.06Å; A190-L432 VanDerWaalsContact O-CG 3.27Å; A190-L432 WeakPolarHBondContact O-CG 3.39Å
191Y38.2Very low34.8Very low25 Ų2542 Ų4210%0.09823%0.226CC..  trans-149.659.5-172.4-59.6-79.9000114.8F98 L148 I187F98-Y191 WeakPolarHBondContact CD1-O 3.33Å; F98-Y191 HydrophobicContact CE1-CD2 4.19Å; F98-Y191 AromaticContact CE1-CG 3.83Å; F98-Y191 HydrophobicContact CE1-CG 3.83Å; F98-Y191 HydrophobicContact CZ-CG 4.35Å; L148-Y191 HydrophobicContact CD2-CE1 4.02Å; I187-Y191 HydrophobicContact CG2-CE2 3.8Å; I187-Y191 VanDerWaalsContact CG2-OH 3.29Å; I187-Y191 WeakPolarHBondContact CG2-OH 3.47Å; I187-Y191 WeakPolarHBondContact O-CE2 3.48Å
192H48.5Very low35.1Very low6 Ų642.1 Ų42.13%0.02823%0.23CC..  trans-126.720.4-149.6-59.2-50.8000121Y103 P189 A190Y103-H192 AromaticContact CD1-CE1 3.06Å; Y103-H192 WeakPolarHBondContact CD1-CE1 3.49Å; Y103-H192 AromaticContact CD1-CG 3.91Å; Y103-H192 AromaticContact CD1-ND1 3.02Å; Y103-H192 WeakPolarHBondContact CD1-ND1 3.43Å; Y103-H192 AromaticContact CD1-NE2 3.92Å; Y103-H192 HydrophobicContact CD2-CB 4.45Å; Y103-H192 AromaticContact CD2-ND1 3.88Å; Y103-H192 AromaticContact CE1-CE1 3.67Å; Y103-H192 AromaticContact CE1-ND1 3.43Å; Y103-H192 WeakPolarHBondContact CE1-ND1 2.94Å; Y103-H192 HydrophobicContact CG-CB 4.37Å; Y103-H192 AromaticContact CG-CE1 3.61Å; Y103-H192 AromaticContact CG-CG 3.67Å; Y103-H192 AromaticContact CG-ND1 3.25Å; P189-H192 VanDerWaalsContact CA-NE2 3.29Å; P189-H192 WeakPolarHBondContact CA-NE2 3.42Å; P189-H192 PolarHBondContact O-CD2 2.71Å; P189-H192 PolarHBondContact O-NE2 2.9Å; A190-H192 PolarHBondContact N-NE2 2.84Å
193V41.3Very low35Very low6 Ų637 Ų374%0.03623%0.227CC..SBendtrans-128-12.6168.5-168.80000113.3L196 L425 F428V193-L196 PolarHBondContact O-N 3.05Å; V193-L425 HydrophobicContact CB-CD2 3.44Å; V193-L425 VanDerWaalsContact CB-CD2 3.44Å; V193-L425 HydrophobicContact CG1-CD2 3.64Å; V193-L425 WeakPolarHBondContact O-CD2 3.48Å; V193-F428 HydrophobicContact CB-CD1 4.39Å; V193-F428 HydrophobicContact CG2-CD1 4.13Å; V193-F428 HydrophobicContact CG2-CE1 3.9Å
194L40.9Very low35.1Very low7 Ų738.3 Ų38.34%0.03724%0.236CC..Hα-helixtrans-62.9-39.5-168.4-127105.6000115.7I141 L145 L196 A198 L425 V429I141-L194 HydrophobicContact CG2-CD2 3.19Å; I141-L194 HydrophobicContact CG2-CG 4.39Å; L145-L194 HydrophobicContact CD1-CB 4.14Å; L145-L194 HydrophobicContact CD1-CD2 3.38Å; L145-L194 HydrophobicContact CD1-CG 4.31Å; L145-L194 HydrophobicContact CD2-CB 4.19Å; L145-L194 HydrophobicContact CD2-CD2 3.73Å; L145-L194 HydrophobicContact CG-CD2 3.52Å; L194-L196 VanDerWaalsContact C-N 3.33Å; L194-L196 PolarHBondContact O-N 2.89Å; L194-A198 PolarHBondContact O-N 3.34Å; L194-L425 HydrophobicContact CB-CD2 4.31Å; L194-L425 HydrophobicContact CD1-CB 3.72Å; L194-L425 HydrophobicContact CD1-CD2 4.03Å; L194-L425 HydrophobicContact CD1-CG 4.42Å; L194-L425 WeakPolarHBondContact CD1-O 3.48Å; L194-L425 HydrophobicContact CG-CB 4.21Å; L194-L425 HydrophobicContact CG-CD1 4.43Å; L194-L425 HydrophobicContact CG-CD2 4.21Å; L194-V429 HydrophobicContact CB-CG2 4.31Å; L194-V429 HydrophobicContact CD1-CB 3.89Å; L194-V429 HydrophobicContact CD1-CG2 3.28Å; L194-V429 HydrophobicContact CG-CG2 4.28Å
195P37.4Very low35.3Very low0 Ų036.7 Ų36.70%023%0.225CC..Hα-helixtrans-70.5-24.1178.5-12.222.9000114.5L36 V95 F98 I197 A198 S199L36-P195 HydrophobicContact CD1-CG 4.24Å; L36-P195 HydrophobicContact CD2-CB 3.79Å; L36-P195 HydrophobicContact CD2-CG 3.9Å; V95-P195 HydrophobicContact CB-CB 4.16Å; V95-P195 HydrophobicContact CB-CG 3.97Å; V95-P195 HydrophobicContact CG1-CB 4.17Å; V95-P195 HydrophobicContact CG1-CG 3.99Å; V95-P195 HydrophobicContact CG2-CB 3.84Å; V95-P195 HydrophobicContact CG2-CG 4.19Å; F98-P195 HydrophobicContact CB-CG 4.21Å; P195-I197 PolarHBondContact O-N 3.3Å; P195-A198 PolarHBondContact O-N 3.45Å; P195-S199 PolarHBondContact O-N 3.41Å; P195-S199 VanDerWaalsContact O-N 3.12Å; P195-S199 PolarHBondContact O-OG 2.93Å
196L39.5Very low35.1Very low5 Ų539.1 Ų39.13%0.02622%0.222CC..Hα-helixtrans-63.6-32.2-175.4-118.8145.7000111.3L36 V193 L194 S199 F340 V344L36-L196 HydrophobicContact CB-CD1 4.26Å; L36-L196 HydrophobicContact CB-CG 4.24Å; L36-L196 HydrophobicContact CD2-CB 3.51Å; L36-L196 HydrophobicContact CD2-CD1 3.57Å; L36-L196 HydrophobicContact CD2-CG 3.6Å; L36-L196 HydrophobicContact CG-CD1 3.82Å; L36-L196 HydrophobicContact CG-CG 4.15Å; V193-L196 PolarHBondContact O-N 3.05Å; L194-L196 VanDerWaalsContact C-N 3.33Å; L194-L196 PolarHBondContact O-N 2.89Å; L196-S199 PolarHBondContact O-OG 2.87Å; L196-F340 HydrophobicContact CD2-CE2 3.91Å; L196-F340 WeakPolarHBondContact O-CE2 3.48Å; L196-V344 HydrophobicContact CD2-CG2 4.18Å
197I37.4Very low35.1Very low2 Ų241.3 Ų41.31%0.0123%0.23CC..Hα-helixtrans-96.3-33.4-178-65.8178.3000111.2P195 S199 M200 Y418 V421 L425P195-I197 PolarHBondContact O-N 3.3Å; I197-S199 PolarHBondContact O-N 2.02Å; I197-M200 HydrophobicContact CB-SD 4.39Å; I197-M200 HydrophobicContact CG1-CE 4.36Å; I197-M200 HydrophobicContact CG1-SD 4.4Å; I197-M200 HydrophobicContact CG2-SD 3.95Å; I197-M200 WeakPolarHBondContact O-CB 3.28Å; I197-M200 PolarHBondContact O-N 3.36Å; I197-M200 VanDerWaalsContact O-N 3.1Å; I197-Y418 HydrophobicContact CG2-CD2 3.77Å; I197-Y418 HydrophobicContact CG2-CE2 3.44Å; I197-Y418 VanDerWaalsContact CG2-CE2 3.44Å; I197-V421 HydrophobicContact CD1-CB 4.05Å; I197-V421 HydrophobicContact CD1-CG1 3.1Å; I197-L425 HydrophobicContact CB-CD1 3.47Å; I197-L425 VanDerWaalsContact CB-CD1 3.47Å; I197-L425 HydrophobicContact CD1-CD1 3.32Å; I197-L425 HydrophobicContact CD1-CG 3.95Å; I197-L425 HydrophobicContact CG1-CD1 3.75Å; I197-L425 HydrophobicContact CG2-CD1 3.94Å
198A37.8Very low35.2Very low22 Ų2247.6 Ų47.618%0.18226%0.264CS..Hα-helixtrans-62.3-24.6173.100000112.8L142 L194 P195L142-A198 HydrophobicContact CD2-CB 3.97Å; L194-A198 PolarHBondContact O-N 3.34Å; P195-A198 PolarHBondContact O-N 3.45Å
199S36.8Very low34.8Very low11 Ų1147.2 Ų47.28%0.07727%0.271CS..THydrogen-bonded Turntrans-93.16.8175.561.90000114.8S33 P195 L196 I197 P201S33-S199 WeakPolarHBondContact CA-OG 3.42Å; S33-S199 WeakPolarHBondContact CB-OG 3.45Å; S33-S199 PolarHBondContact N-OG 2.88Å; S33-S199 VanDerWaalsContact N-OG 3.15Å; P195-S199 PolarHBondContact O-N 3.41Å; P195-S199 VanDerWaalsContact O-N 3.12Å; P195-S199 PolarHBondContact O-OG 2.93Å; L196-S199 PolarHBondContact O-OG 2.87Å; I197-S199 PolarHBondContact O-N 2.02Å; S199-P201 VanDerWaalsContact O-CD 3.3Å; S199-P201 WeakPolarHBondContact O-CD 3.08Å
200M36.7Very low34.8Very low34 Ų3452.4 Ų52.417%0.16730%0.296CS..  trans-62122.4176.4-79.8175.1154.100110I197 A202 F205 L290 F340I197-M200 HydrophobicContact CB-SD 4.39Å; I197-M200 HydrophobicContact CG1-CE 4.36Å; I197-M200 HydrophobicContact CG1-SD 4.4Å; I197-M200 HydrophobicContact CG2-SD 3.95Å; I197-M200 WeakPolarHBondContact O-CB 3.28Å; I197-M200 PolarHBondContact O-N 3.36Å; I197-M200 VanDerWaalsContact O-N 3.1Å; M200-A202 PolarHBondContact O-N 3.48Å; M200-F205 HydrophobicContact CB-CE2 3.91Å; M200-F205 HydrophobicContact CB-CZ 4.41Å; M200-F205 HydrophobicContact CE-CZ 4.43Å; M200-F205 HydrophobicContact CG-CE2 4.5Å; M200-F205 HydrophobicContact SD-CE2 3.98Å; M200-F205 HydrophobicContact SD-CZ 3.71Å; M200-L290 HydrophobicContact CE-CD1 3.42Å; M200-L290 VanDerWaalsContact CE-CD1 3.42Å; M200-F340 HydrophobicContact CE-CE1 3.55Å; M200-F340 HydrophobicContact CE-CE2 4.06Å; M200-F340 HydrophobicContact CE-CZ 3.19Å; M200-F340 HydrophobicContact CG-CE2 3.92Å; M200-F340 HydrophobicContact CG-CZ 3.99Å; M200-F340 HydrophobicContact SD-CZ 4.42Å
201P34.7Very low35Very low38 Ų3857.4 Ų57.425%0.24734%0.338CS..  trans-60.2127.7176.8-21.831.2000110.7S199 A203 L204S199-P201 VanDerWaalsContact O-CD 3.3Å; S199-P201 WeakPolarHBondContact O-CD 3.08Å; P201-A203 HydrophobicContact CB-CB 4.43Å; P201-A203 PolarHBondContact O-N 2.96Å; P201-L204 PolarHBondContact O-N 3.04Å
202A34.7Very low34.6Very low58 Ų5860.7 Ų60.748%0.47936%0.364SS..G310 helixtrans-54.3-24.4171.500000112.4M200 L204 F205 W206M200-A202 PolarHBondContact O-N 3.48Å; A202-L204 VanDerWaalsContact C-N 3.3Å; A202-L204 PolarHBondContact O-N 2.91Å; A202-F205 CarbonylContact O-C 3.57Å; A202-F205 PolarHBondContact O-N 3.19Å; A202-W206 HydrophobicContact CB-CE3 4.42Å; A202-W206 PolarHBondContact O-N 2.83Å
203A26.9Very low33.7Very low75 Ų7569.4 Ų69.462%0.6241%0.405SS*.G310 helixtrans-64.9-24.8176.200000114.5P201 F205P201-A203 HydrophobicContact CB-CB 4.43Å; P201-A203 PolarHBondContact O-N 2.96Å; A203-F205 PolarHBondContact O-N 3.44Å
204L34.1Very low33.1Very low74 Ų7477.1 Ų77.139%0.38745%0.446SS..G310 helixtrans-69.4-19.6170.4-79.4170000111.9P201 A202 F340P201-L204 PolarHBondContact O-N 3.04Å; A202-L204 VanDerWaalsContact C-N 3.3Å; A202-L204 PolarHBondContact O-N 2.91Å; L204-F340 HydrophobicContact CD1-CD1 4.45Å
205F32Very low32.5Very low51 Ų5185.1 Ų85.122%0.22449%0.487CS..THydrogen-bonded Turntrans-110.3-22.4-174.9-55.1-44.2000113.1M200 A202 A203 D414M200-F205 HydrophobicContact CB-CE2 3.91Å; M200-F205 HydrophobicContact CB-CZ 4.41Å; M200-F205 HydrophobicContact CE-CZ 4.43Å; M200-F205 HydrophobicContact CG-CE2 4.5Å; M200-F205 HydrophobicContact SD-CE2 3.98Å; M200-F205 HydrophobicContact SD-CZ 3.71Å; A202-F205 CarbonylContact O-C 3.57Å; A202-F205 PolarHBondContact O-N 3.19Å; A203-F205 PolarHBondContact O-N 3.44Å; F205-D414 HydrophobicContact CD1-CB 3.14Å; F205-D414 WeakPolarHBondContact CD1-OD2 3.47Å; F205-D414 HydrophobicContact CE1-CB 3.13Å; F205-D414 HydrophobicContact CG-CB 3.92Å; F205-D414 HydrophobicContact CZ-CB 3.96Å
206W27.8Very low31.9Very low137 Ų13790.6 Ų90.652%0.51953%0.525SS..  trans-139.885-177.8-68-33.1000112A202 N208 L209A202-W206 HydrophobicContact CB-CE3 4.42Å; A202-W206 PolarHBondContact O-N 2.83Å; W206-N208 PolarHBondContact O-N 2.9Å; W206-L209 HydrophobicContact CB-CD1 3.87Å; W206-L209 HydrophobicContact CD2-CD1 3.41Å; W206-L209 VanDerWaalsContact CD2-CD1 3.41Å; W206-L209 HydrophobicContact CE3-CD1 3.25Å; W206-L209 HydrophobicContact CG-CD1 3.72Å; W206-L209 HydrophobicContact CZ3-CD1 3.87Å
207P28.6Very low31.2Very low113 Ų11398.7 Ų98.773%0.73457%0.568SS**THydrogen-bonded Turntrans-68.61.1176.324.4-30.3000114.4
208N28.9Very low30.6Very low153 Ų153106.8 Ų106.882%0.81861%0.608SS**THydrogen-bonded Turntrans-140.753.7-175.7-81.8-36.3000114.5W206W206-N208 PolarHBondContact O-N 2.9Å
209L29Very low30Very low121 Ų121113.9 Ų113.963%0.63464%0.642SS**  trans-114.9108.2166.1-86.8161.3000110.9W206W206-L209 HydrophobicContact CB-CD1 3.87Å; W206-L209 HydrophobicContact CD2-CD1 3.41Å; W206-L209 VanDerWaalsContact CD2-CD1 3.41Å; W206-L209 HydrophobicContact CE3-CD1 3.25Å; W206-L209 HydrophobicContact CG-CD1 3.72Å; W206-L209 HydrophobicContact CZ3-CD1 3.87Å
210N31Very low29.5Very low154 Ų154119.3 Ų119.382%0.82468%0.679SS**  trans-57133.6174.1-79.4-26000111S212N210-S212 PolarHBondContact O-N 3Å
211A33.4Very low29.1Very low114 Ų114125 Ų12594%0.94271%0.71SS**SBendtrans-71.430.7-169.300000116.2
212S30Very low28.7Very low94 Ų94133.5 Ų133.566%0.65774%0.743SS**  trans-123.266-17471.80000113.3N210N210-S212 PolarHBondContact O-N 3Å
213Q29.5Very low28.6Very low188 Ų188137.6 Ų137.688%0.87976%0.755SS**SBendtrans-169.455163.1-110.716529.600113.9
214N27.4Very low28.7Very low168 Ų168143.8 Ų143.890%0.89877%0.768SS**  trans-146.532.4176.5-107-28.3000117
215I28Very low28.7Very low175 Ų175150.1 Ų150.190%0.89779%0.793SS**  trans-127.582.6174.3-51.5175.8000109.3
216S25.1Very low28.7Very low116 Ų116157.1 Ų157.181%0.81182%0.823SS**SBendtrans-174.540.3152.8-149.70000114.9
217L25.2Very low29.6Very low175 Ų175156 Ų15692%0.91683%0.833SS**  trans-14751.8175.8-114.5151.5000112.2
218M24.7Very low30.2Very low172 Ų172157.4 Ų157.485%0.84783%0.83SS**  trans-144.4123.5160.7-86.6-143.5-91.400107.9
219L26.4Very low31Very low171 Ų171161.2 Ų161.290%0.89583%0.833SS**  trans121.373.6168.6-71.6144.6000113.9
220S25.3Very low31.4Very low124 Ų124162.5 Ų162.587%0.86784%0.837SS**  trans-16662.7146-83.10000111.1
221L27.6Very low32.1Very low155 Ų155157.7 Ų157.781%0.81282%0.819SS**  trans-124.674.1162.7-87.2162.3000108.4I223L221-I223 HydrophobicContact CD2-CD1 3.61Å; L221-I223 HydrophobicContact CD2-CG1 4.08Å
222K26.2Very low32.5Very low215 Ų215153.1 Ų153.194%0.93578%0.779SS**  trans-87.188.9159.1-87.6-177.7176.1175.10107.1
223I33.6Very low33Very low145 Ų145157.8 Ų157.874%0.74478%0.782SS**  trans-110.1125.5168.7-61.5-178.1000108.6L221L221-I223 HydrophobicContact CD2-CD1 3.61Å; L221-I223 HydrophobicContact CD2-CG1 4.08Å
224K29.9Very low33.5Very low205 Ų205154 Ų15489%0.89177%0.768SS**  trans-66.1142.4-174.5-86.8173169.3174.50111.9
225K32.6Very low34.3Very low207 Ų207148.6 Ų148.690%0.974%0.741SS**  trans-46.3128171.4-70.1175.1170.41790115
226K33.3Very low35Very low197 Ų197141 Ų14186%0.85770%0.702SS**  trans147.7155138.7-92.8-175.4171.3-177.30111.7
227P45.7Very low36.1Very low113 Ų113137.8 Ų137.873%0.73468%0.68SS**  -109.7110.9-68.731.2-12.3000110.8R229P227-R229 VanDerWaalsContact C-N 3.32Å; P227-R229 PolarHBondContact O-N 3.28Å
228E42.1Very low37.1Very low144 Ų144133 Ų13367%0.67365%0.654SS**  trans-83.522.4-171.2-70178.1150.100115.9M230 A231E228-M230 VanDerWaalsContact C-N 3.32Å; E228-M230 PolarHBondContact O-N 3.47Å; E228-M230 VanDerWaalsContact O-N 3.16Å; E228-A231 PolarHBondContact O-N 3.46Å
229R45Very low38.5Very low232 Ų232127.2 Ų127.288%0.87563%0.631SS**THydrogen-bonded Turntrans-71-15.1-166.6-72-172.1-172.4174.91.1116.4P227P227-R229 VanDerWaalsContact C-N 3.32Å; P227-R229 PolarHBondContact O-N 3.28Å
230M38.2Very low39.8Very low148 Ų148119.3 Ų119.373%0.72959%0.59SS**THydrogen-bonded Turntrans-106.8-13.9177.9-77.8-169.8-178.100114.7E228 D232E228-M230 VanDerWaalsContact C-N 3.32Å; E228-M230 PolarHBondContact O-N 3.47Å; E228-M230 VanDerWaalsContact O-N 3.16Å; M230-D232 VanDerWaalsContact C-N 3.33Å; M230-D232 PolarHBondContact O-N 2.72Å
231A45.2Very low41.5Very low54 Ų54115.8 Ų115.845%0.44657%0.565SS.*Hα-helixtrans-68.5-34.6-175.600000112.1E228 R233 L234 T235E228-A231 PolarHBondContact O-N 3.46Å; A231-R233 PolarHBondContact O-N 2.72Å; A231-L234 PolarHBondContact O-N 2.64Å; A231-T235 PolarHBondContact O-N 2.69Å; A231-T235 PolarHBondContact O-OG1 3.27Å
232D42.5Very low42.9Very low18 Ų18112.8 Ų112.810%0.09655%0.55CS..Hα-helixtrans-73.6-34.2-163.5-66-9.3000114.5R150 L151 M230 T235R150-D232 VanDerWaalsContact CZ-CG 3.43Å; R150-D232 IonicContact CZ-OD1 2.61Å; R150-D232 IonicContact CZ-OD2 2.72Å; R150-D232 VanDerWaalsContact NH1-CG 3.31Å; R150-D232 IonicContact NH1-OD1 3.26Å; R150-D232 PolarHBondContact NH1-OD1 2.92Å; R150-D232 IonicContact NH1-OD2 2.72Å; R150-D232 PolarHBondContact NH1-OD2 3.12Å; R150-D232 IonicContact NH2-OD1 2.81Å; R150-D232 PolarHBondContact NH2-OD1 3.41Å; R150-D232 IonicContact NH2-OD2 3.9Å; R150-D232 PolarHBondContact NH2-OD2 2.88Å; L151-D232 HydrophobicContact CD2-CB 3.93Å; M230-D232 VanDerWaalsContact C-N 3.33Å; M230-D232 PolarHBondContact O-N 2.72Å; D232-T235 WeakPolarHBondContact CA-OG1 3.36Å; D232-T235 PolarHBondContact O-N 3.29Å; D232-T235 PolarHBondContact O-OG1 3.27Å
233R40.5Very low44.2Very low191 Ų191104.8 Ų104.872%0.72152%0.515SS*.Hα-helixtrans-70.4-34.7175.6-74.9-171-174.1-174.84.1112A231A231-R233 PolarHBondContact O-N 2.72Å
234L39.7Very low45.5Very low110 Ų11098.9 Ų98.958%0.57648%0.484SS*.Hα-helixtrans-65.4-42174.3-105.2102000110.6A231 V236 S237 L238A231-L234 PolarHBondContact O-N 2.64Å; L234-V236 PolarHBondContact O-N 3.41Å; L234-S237 PolarHBondContact O-N 3.33Å; L234-S237 PolarHBondContact O-OG 3.49Å; L234-L238 HydrophobicContact CB-CD1 4.32Å; L234-L238 WeakPolarHBondContact O-CD1 3.24Å; L234-L238 WeakPolarHBondContact O-CG 3.29Å; L234-L238 PolarHBondContact O-N 2.95Å
235T44.6Very low47.1Very low54 Ų5492.2 Ų92.233%0.33146%0.461SS..Hα-helixtrans-60.4-39.9-170.7-20.20000113.8A231 D232 L238 C239A231-T235 PolarHBondContact O-N 2.69Å; A231-T235 PolarHBondContact O-OG1 3.27Å; D232-T235 WeakPolarHBondContact CA-OG1 3.36Å; D232-T235 PolarHBondContact O-N 3.29Å; D232-T235 PolarHBondContact O-OG1 3.27Å; T235-L238 WeakPolarHBondContact O-CB 3.34Å; T235-L238 PolarHBondContact O-N 3.22Å; T235-C239 PolarHBondContact O-N 3.35Å; T235-C239 PolarHBondContact O-SG 3.49Å; T235-C239 VanDerWaalsContact O-SG 3.4Å
236V41.8Very low48.1Very low15 Ų1586.1 Ų86.19%0.09144%0.438CS..Hα-helixtrans-83.7-27.2-179.5164.30000112.6L148 L151 L234 L238 C239 T240 R433L148-V236 HydrophobicContact CD2-CG1 4.38Å; L151-V236 HydrophobicContact CD1-CB 3.47Å; L151-V236 VanDerWaalsContact CD1-CB 3.47Å; L151-V236 HydrophobicContact CD1-CG1 4Å; L151-V236 HydrophobicContact CD1-CG2 3.19Å; L151-V236 HydrophobicContact CG-CG2 4.46Å; L234-V236 PolarHBondContact O-N 3.41Å; V236-L238 PolarHBondContact O-N 3.13Å; V236-C239 PolarHBondContact O-N 3.19Å; V236-T240 PolarHBondContact O-N 3.4Å; V236-R433 PolarHBondContact O-NH1 3.43Å; V236-R433 PolarHBondContact O-NH2 3.33Å
237S47.8Very low49Very low48 Ų4876.9 Ų76.934%0.33640%0.397SS..Hα-helixtrans-60.2-39.3165.181.40000110.9L234 T240 S241L234-S237 PolarHBondContact O-N 3.33Å; L234-S237 PolarHBondContact O-OG 3.49Å; S237-T240 PolarHBondContact O-N 3.24Å; S237-S241 WeakPolarHBondContact O-CB 3.05Å; S237-S241 PolarHBondContact O-N 3.31Å; S237-S241 PolarHBondContact O-OG 3.46Å
238L47.2Very low50Low74 Ų7478.6 Ų78.639%0.38739%0.389SS..Hα-helixtrans-62-49.5176-69.1160000110.7L234 T235 V236 T240 S241 D242L234-L238 HydrophobicContact CB-CD1 4.32Å; L234-L238 WeakPolarHBondContact O-CD1 3.24Å; L234-L238 WeakPolarHBondContact O-CG 3.29Å; L234-L238 PolarHBondContact O-N 2.95Å; T235-L238 WeakPolarHBondContact O-CB 3.34Å; T235-L238 PolarHBondContact O-N 3.22Å; V236-L238 PolarHBondContact O-N 3.13Å; L238-T240 VanDerWaalsContact C-N 3.32Å; L238-T240 PolarHBondContact O-N 3.12Å; L238-T240 VanDerWaalsContact O-N 3.16Å; L238-S241 WeakPolarHBondContact CA-OG 3.02Å; L238-S241 PolarHBondContact O-N 2.92Å; L238-S241 PolarHBondContact O-OG 3.47Å; L238-D242 WeakPolarHBondContact O-CB 3.46Å; L238-D242 PolarHBondContact O-N 3.44Å
239C53Low51.1Low52 Ų5278.3 Ų78.335%0.35139%0.388SS..Hα-helixtrans-56.5-40.8-179.2-660000114.4T235 V236 F243T235-C239 PolarHBondContact O-N 3.35Å; T235-C239 PolarHBondContact O-SG 3.49Å; T235-C239 VanDerWaalsContact O-SG 3.4Å; V236-C239 PolarHBondContact O-N 3.19Å; C239-F243 WeakPolarHBondContact O-CB 3.04Å; C239-F243 PolarHBondContact O-N 2.82Å; C239-F243 VanDerWaalsContact O-N 3.13Å
240T53.5Low51.3Low5 Ų572.1 Ų72.13%0.03137%0.372CS..Hα-helixtrans-78.9-40.2178.9-59.40000112.2V236 S237 L238 D242 F243 E244 F256 R433V236-T240 PolarHBondContact O-N 3.4Å; S237-T240 PolarHBondContact O-N 3.24Å; L238-T240 VanDerWaalsContact C-N 3.32Å; L238-T240 PolarHBondContact O-N 3.12Å; L238-T240 VanDerWaalsContact O-N 3.16Å; T240-D242 VanDerWaalsContact C-N 3.29Å; T240-D242 PolarHBondContact O-N 3.35Å; T240-F243 PolarHBondContact O-N 3.47Å; T240-E244 HydrophobicContact CG2-CG 4.46Å; T240-E244 WeakPolarHBondContact O-CG 3.4Å; T240-E244 PolarHBondContact O-N 2.94Å; T240-F256 HydrophobicContact CG2-CE2 4.21Å; T240-R433 WeakPolarHBondContact OG1-CD 3.12Å; T240-R433 PolarHBondContact OG1-NH1 2.73Å
241S60.8Low52.9Low50 Ų5073.6 Ų73.635%0.3537%0.374SS..Hα-helixtrans-63-40.1175.158.60000111.3S237 L238 F243 E244 T245S237-S241 WeakPolarHBondContact O-CB 3.05Å; S237-S241 PolarHBondContact O-N 3.31Å; S237-S241 PolarHBondContact O-OG 3.46Å; L238-S241 WeakPolarHBondContact CA-OG 3.02Å; L238-S241 PolarHBondContact O-N 2.92Å; L238-S241 PolarHBondContact O-OG 3.47Å; S241-F243 VanDerWaalsContact C-N 3.34Å; S241-E244 PolarHBondContact O-N 3.3Å; S241-T245 WeakPolarHBondContact O-CB 3.45Å; S241-T245 PolarHBondContact O-N 3.14Å; S241-T245 PolarHBondContact O-OG1 3.17Å
242D59Low53.6Low92 Ų9272.8 Ų72.849%0.49236%0.36SS..Hα-helixtrans-65.1-42.7179.5-64.9-10.1000109.9L238 T240 T245 L246L238-D242 WeakPolarHBondContact O-CB 3.46Å; L238-D242 PolarHBondContact O-N 3.44Å; T240-D242 VanDerWaalsContact C-N 3.29Å; T240-D242 PolarHBondContact O-N 3.35Å; D242-T245 PolarHBondContact O-N 3.3Å; D242-L246 WeakPolarHBondContact O-CB 3.42Å; D242-L246 PolarHBondContact O-N 2.96Å
243F52.4Low55Low46 Ų4682.9 Ų82.920%0.20240%0.397CS..Hα-helixtrans-72.2-40.7177.4-161.1-75.7000112.9C239 T240 S241 T245 L246 L247 F256 L430C239-F243 WeakPolarHBondContact O-CB 3.04Å; C239-F243 PolarHBondContact O-N 2.82Å; C239-F243 VanDerWaalsContact O-N 3.13Å; T240-F243 PolarHBondContact O-N 3.47Å; S241-F243 VanDerWaalsContact C-N 3.34Å; F243-T245 PolarHBondContact O-N 3.37Å; F243-L246 CarbonylContact O-C 3.27Å; F243-L246 WeakPolarHBondContact O-CB 3.27Å; F243-L246 PolarHBondContact O-N 3.23Å; F243-L247 HydrophobicContact CD1-CD1 3.74Å; F243-L247 HydrophobicContact CD1-CD2 4.25Å; F243-L247 HydrophobicContact CD1-CG 3.57Å; F243-L247 HydrophobicContact CE1-CD1 3.62Å; F243-L247 HydrophobicContact CE1-CD2 3.65Å; F243-L247 HydrophobicContact CE1-CG 3.47Å; F243-L247 VanDerWaalsContact CE1-CG 3.47Å; F243-L247 HydrophobicContact CZ-CD2 4.44Å; F243-L247 WeakPolarHBondContact O-CB 3.5Å; F243-L247 WeakPolarHBondContact O-CG 3.46Å; F243-L247 PolarHBondContact O-N 3Å; F243-F256 HydrophobicContact CB-CZ 4.01Å; F243-F256 HydrophobicContact CD1-CD1 4.33Å; F243-F256 AromaticContact CD1-CE1 3.09Å; F243-F256 HydrophobicContact CD1-CE1 3.09Å; F243-F256 HydrophobicContact CD1-CE2 4.42Å; F243-F256 AromaticContact CD1-CZ 3.14Å; F243-F256 HydrophobicContact CD1-CZ 3.14Å; F243-F256 HydrophobicContact CE1-CD1 4.21Å; F243-F256 AromaticContact CE1-CE1 3.21Å; F243-F256 HydrophobicContact CE1-CE1 3.21Å; F243-F256 AromaticContact CE1-CZ 3.82Å; F243-F256 HydrophobicContact CE1-CZ 3.82Å; F243-F256 HydrophobicContact CG-CE1 4.1Å; F243-F256 AromaticContact CG-CZ 3.88Å; F243-F256 HydrophobicContact CG-CZ 3.88Å; F243-F256 HydrophobicContact CZ-CE1 4.32Å; F243-L430 HydrophobicContact CB-CD1 4.01Å; F243-L430 HydrophobicContact CB-CD2 4.34Å; F243-L430 HydrophobicContact CD1-CD1 3.39Å; F243-L430 HydrophobicContact CD2-CD1 3.43Å; F243-L430 VanDerWaalsContact CD2-CD1 3.43Å; F243-L430 HydrophobicContact CE1-CD1 3.48Å; F243-L430 VanDerWaalsContact CE1-CD1 3.48Å; F243-L430 HydrophobicContact CE2-CD1 3.55Å; F243-L430 HydrophobicContact CG-CD1 3.32Å; F243-L430 HydrophobicContact CZ-CD1 3.54Å
244E60.5Low56.5Low22 Ų2277 Ų7710%0.10339%0.385CS..Hα-helixtrans-60.5-39.4171.9-76.1-171.3-152.700111.6T240 S241 L246 L247 R248 F256 M434T240-E244 HydrophobicContact CG2-CG 4.46Å; T240-E244 WeakPolarHBondContact O-CG 3.4Å; T240-E244 PolarHBondContact O-N 2.94Å; S241-E244 PolarHBondContact O-N 3.3Å; E244-L246 VanDerWaalsContact C-N 3.34Å; E244-L247 PolarHBondContact O-N 3.23Å; E244-R248 WeakPolarHBondContact O-CB 3.44Å; E244-R248 VanDerWaalsContact O-CG 3.26Å; E244-R248 WeakPolarHBondContact O-CG 3.26Å; E244-R248 PolarHBondContact O-N 3.44Å; E244-R248 IonicContact OE2-CZ 3.15Å; E244-R248 IonicContact OE2-NH2 3.42Å; E244-R248 PolarHBondContact OE2-NH2 3.38Å; E244-F256 HydrophobicContact CB-CE2 4.48Å; E244-F256 HydrophobicContact CG-CD2 3.94Å; E244-F256 HydrophobicContact CG-CE2 3.34Å; E244-F256 HydrophobicContact CG-CZ 4.2Å; E244-M434 WeakPolarHBondContact OE1-CE 3.38Å
245T63.7Low57.8Low65 Ų6572.1 Ų72.140%0.39936%0.36SS..Hα-helixtrans-63-45.5176.6-60.40000109.8S241 D242 F243 L247 R248 Q249S241-T245 WeakPolarHBondContact O-CB 3.45Å; S241-T245 PolarHBondContact O-N 3.14Å; S241-T245 PolarHBondContact O-OG1 3.17Å; D242-T245 PolarHBondContact O-N 3.3Å; F243-T245 PolarHBondContact O-N 3.37Å; T245-L247 VanDerWaalsContact C-N 3.35Å; T245-L247 PolarHBondContact O-N 3.1Å; T245-R248 PolarHBondContact O-N 3.37Å; T245-Q249 VanDerWaalsContact O-CG 3.29Å; T245-Q249 WeakPolarHBondContact O-CG 3.39Å; T245-Q249 PolarHBondContact O-N 2.96Å
246L53.1Low58.6Low79 Ų7969.5 Ų69.541%0.41435%0.345SS..Hα-helixtrans-60.3-42.9173.8-173.167.5000111.6D242 F243 E244 R248 Q249 L250D242-L246 WeakPolarHBondContact O-CB 3.42Å; D242-L246 PolarHBondContact O-N 2.96Å; F243-L246 CarbonylContact O-C 3.27Å; F243-L246 WeakPolarHBondContact O-CB 3.27Å; F243-L246 PolarHBondContact O-N 3.23Å; E244-L246 VanDerWaalsContact C-N 3.34Å; L246-R248 PolarHBondContact O-N 3.48Å; L246-Q249 WeakPolarHBondContact O-CB 3.32Å; L246-Q249 PolarHBondContact O-N 3.29Å; L246-L250 HydrophobicContact CG-CD1 4.29Å; L246-L250 WeakPolarHBondContact O-CB 3.34Å; L246-L250 VanDerWaalsContact O-CG 3.28Å; L246-L250 WeakPolarHBondContact O-CG 3.44Å; L246-L250 PolarHBondContact O-N 2.9Å
247L52.5Low60Low2 Ų270.9 Ų70.91%0.0135%0.35CS..Hα-helixtrans-63.9-40.5176.3-76.5-174.6000112.6F243 E244 T245 Q249 L250 K251 Y252 F256 L259F243-L247 HydrophobicContact CD1-CD1 3.74Å; F243-L247 HydrophobicContact CD1-CD2 4.25Å; F243-L247 HydrophobicContact CD1-CG 3.57Å; F243-L247 HydrophobicContact CE1-CD1 3.62Å; F243-L247 HydrophobicContact CE1-CD2 3.65Å; F243-L247 HydrophobicContact CE1-CG 3.47Å; F243-L247 VanDerWaalsContact CE1-CG 3.47Å; F243-L247 HydrophobicContact CZ-CD2 4.44Å; F243-L247 WeakPolarHBondContact O-CB 3.5Å; F243-L247 WeakPolarHBondContact O-CG 3.46Å; F243-L247 PolarHBondContact O-N 3Å; E244-L247 PolarHBondContact O-N 3.23Å; T245-L247 VanDerWaalsContact C-N 3.35Å; T245-L247 PolarHBondContact O-N 3.1Å; L247-Q249 VanDerWaalsContact C-N 3.32Å; L247-L250 CarbonylContact O-C 3.42Å; L247-L250 VanDerWaalsContact O-C 3.25Å; L247-L250 WeakPolarHBondContact O-CA 3.32Å; L247-L250 PolarHBondContact O-N 3.06Å; L247-L250 VanDerWaalsContact O-N 3.16Å; L247-K251 PolarHBondContact O-N 3.02Å; L247-K251 VanDerWaalsContact O-N 3.14Å; L247-Y252 HydrophobicContact CD2-CD2 3.91Å; L247-Y252 HydrophobicContact CD2-CG 4.43Å; L247-Y252 WeakPolarHBondContact O-CB 3.35Å; L247-Y252 PolarHBondContact O-N 3.46Å; L247-F256 HydrophobicContact CD1-CD1 3.51Å; L247-F256 HydrophobicContact CD1-CD2 4.35Å; L247-F256 HydrophobicContact CD1-CE1 3.4Å; L247-F256 VanDerWaalsContact CD1-CE1 3.4Å; L247-F256 HydrophobicContact CD1-CE2 4.35Å; L247-F256 HydrophobicContact CD1-CG 3.97Å; L247-F256 HydrophobicContact CD1-CZ 3.86Å; L247-F256 HydrophobicContact CG-CE1 4.42Å; L247-L259 HydrophobicContact CD2-CD2 3.51Å
248R67.2Low61Low150 Ų15070.3 Ų70.357%0.56634%0.342SS*.Hα-helixtrans-65.1-38.7174.7-71.3174.4-161.4168.29.8111E244 T245 L246 L250 K251E244-R248 WeakPolarHBondContact O-CB 3.44Å; E244-R248 VanDerWaalsContact O-CG 3.26Å; E244-R248 WeakPolarHBondContact O-CG 3.26Å; E244-R248 PolarHBondContact O-N 3.44Å; E244-R248 IonicContact OE2-CZ 3.15Å; E244-R248 IonicContact OE2-NH2 3.42Å; E244-R248 PolarHBondContact OE2-NH2 3.38Å; T245-R248 PolarHBondContact O-N 3.37Å; L246-R248 PolarHBondContact O-N 3.48Å; R248-L250 VanDerWaalsContact C-N 3.29Å; R248-L250 PolarHBondContact O-N 3.28Å; R248-K251 WeakPolarHBondContact O-CA 3.26Å; R248-K251 PolarHBondContact O-N 3.46Å
249Q64.9Low61.9Low137 Ų13768.1 Ų68.164%0.6433%0.331SS*.Hα-helixtrans-61.8-38.8171.5-71.5171-2.100111.2T245 L246 L247 K251T245-Q249 VanDerWaalsContact O-CG 3.29Å; T245-Q249 WeakPolarHBondContact O-CG 3.39Å; T245-Q249 PolarHBondContact O-N 2.96Å; L246-Q249 WeakPolarHBondContact O-CB 3.32Å; L246-Q249 PolarHBondContact O-N 3.29Å; L247-Q249 VanDerWaalsContact C-N 3.32Å; Q249-K251 PolarHBondContact O-N 3.46Å
250L50.2Low62.8Low103 Ų10365.8 Ų65.854%0.53932%0.315SS..THydrogen-bonded Turntrans-77.113.4172-64.3173.3000113.7L246 L247 R248 Y252L246-L250 HydrophobicContact CG-CD1 4.29Å; L246-L250 WeakPolarHBondContact O-CB 3.34Å; L246-L250 VanDerWaalsContact O-CG 3.28Å; L246-L250 WeakPolarHBondContact O-CG 3.44Å; L246-L250 PolarHBondContact O-N 2.9Å; L247-L250 CarbonylContact O-C 3.42Å; L247-L250 VanDerWaalsContact O-C 3.25Å; L247-L250 WeakPolarHBondContact O-CA 3.32Å; L247-L250 PolarHBondContact O-N 3.06Å; L247-L250 VanDerWaalsContact O-N 3.16Å; R248-L250 VanDerWaalsContact C-N 3.29Å; R248-L250 PolarHBondContact O-N 3.28Å; L250-Y252 VanDerWaalsContact C-N 3.28Å; L250-Y252 HydrophobicContact CB-CD2 3.85Å; L250-Y252 HydrophobicContact CB-CE2 4.09Å; L250-Y252 PolarHBondContact O-N 2.87Å
251K71.2Confident63.9Low179 Ų17966.6 Ų66.678%0.77832%0.319SS*.THydrogen-bonded Turntrans67.512.5176.1-55.2178.7178.91740116.4L247 R248 Q249 R253L247-K251 PolarHBondContact O-N 3.02Å; L247-K251 VanDerWaalsContact O-N 3.14Å; R248-K251 WeakPolarHBondContact O-CA 3.26Å; R248-K251 PolarHBondContact O-N 3.46Å; Q249-K251 PolarHBondContact O-N 3.46Å; K251-R253 PolarHBondContact O-N 3.28Å
252Y60.4Low64.4Low36 Ų3665.8 Ų65.814%0.14131%0.309CS..  trans-78.287.7169.9-66.6-78.9000110.5L247 L250 S254 G255 E258 L259 E262L247-Y252 HydrophobicContact CD2-CD2 3.91Å; L247-Y252 HydrophobicContact CD2-CG 4.43Å; L247-Y252 WeakPolarHBondContact O-CB 3.35Å; L247-Y252 PolarHBondContact O-N 3.46Å; L250-Y252 VanDerWaalsContact C-N 3.28Å; L250-Y252 HydrophobicContact CB-CD2 3.85Å; L250-Y252 HydrophobicContact CB-CE2 4.09Å; L250-Y252 PolarHBondContact O-N 2.87Å; Y252-S254 VanDerWaalsContact C-N 3.34Å; Y252-S254 PolarHBondContact O-N 3.5Å; Y252-G255 WeakPolarHBondContact O-CA 3.3Å; Y252-G255 PolarHBondContact O-N 2.73Å; Y252-E258 HydrophobicContact CD1-CB 3.87Å; Y252-E258 HydrophobicContact CD1-CG 3.93Å; Y252-L259 HydrophobicContact CD1-CB 3.66Å; Y252-L259 HydrophobicContact CD2-CB 4.43Å; Y252-L259 HydrophobicContact CE1-CB 3.54Å; Y252-L259 HydrophobicContact CE1-CD1 3.99Å; Y252-L259 HydrophobicContact CE1-CG 4.32Å; Y252-L259 HydrophobicContact CE2-CB 4.37Å; Y252-L259 HydrophobicContact CE2-CD1 4.28Å; Y252-L259 HydrophobicContact CE2-CD2 4.49Å; Y252-L259 HydrophobicContact CG-CB 4.09Å; Y252-L259 WeakPolarHBondContact OH-CD1 3.24Å; Y252-E262 VanDerWaalsContact CE1-OE2 3.26Å; Y252-E262 WeakPolarHBondContact CE1-OE2 3.5Å; Y252-E262 PolarHBondContact OH-OE1 2.78Å
253R71.8Confident65.1Low231 Ų23161.9 Ų61.987%0.87229%0.288SS*.THydrogen-bonded Turntrans-64.5-37.6-174.3-67.1-174.4179.9-174.80.4112.8K251 G255 E258K251-R253 PolarHBondContact O-N 3.28Å; R253-G255 PolarHBondContact O-N 3.24Å; R253-E258 PolarHBondContact N-OE2 3.4Å; R253-E258 VanDerWaalsContact N-OE2 3.1Å
254S71.4Confident66.5Low68 Ų6860 Ų6048%0.47628%0.28SS..THydrogen-bonded Turntrans-88.812.5174.351.80000113.1Y252 F256 E257 E258Y252-S254 VanDerWaalsContact C-N 3.34Å; Y252-S254 PolarHBondContact O-N 3.5Å; S254-F256 PolarHBondContact O-N 3.32Å; S254-E257 PolarHBondContact O-N 3.2Å; S254-E258 PolarHBondContact N-OE2 3.22Å; S254-E258 VanDerWaalsContact OG-CB 3.23Å; S254-E258 WeakPolarHBondContact OG-CB 3.19Å; S254-E258 PolarHBondContact OG-OE2 3.37Å
255G67.7Low67.5Low6 Ų658.9 Ų58.96%0.06228%0.275CS..G310 helixtrans56.8-127.5174.700000111.9Y252 R253 E257 E258 L259Y252-G255 WeakPolarHBondContact O-CA 3.3Å; Y252-G255 PolarHBondContact O-N 2.73Å; R253-G255 PolarHBondContact O-N 3.24Å; G255-E257 PolarHBondContact O-N 2.84Å; G255-E257 VanDerWaalsContact O-N 3.12Å; G255-E258 PolarHBondContact O-N 3.21Å; G255-E258 VanDerWaalsContact O-N 3.13Å; G255-L259 PolarHBondContact O-N 2.7Å
256F61.7Low68.1Low0 Ų056.3 Ų56.30%026%0.259CS..G310 helixtrans-65.8-7.9-176.8-65.7-66.5000116.6T240 F243 E244 L247 S254 F427 L430 T431 M434T240-F256 HydrophobicContact CG2-CE2 4.21Å; F243-F256 HydrophobicContact CB-CZ 4.01Å; F243-F256 HydrophobicContact CD1-CD1 4.33Å; F243-F256 AromaticContact CD1-CE1 3.09Å; F243-F256 HydrophobicContact CD1-CE1 3.09Å; F243-F256 HydrophobicContact CD1-CE2 4.42Å; F243-F256 AromaticContact CD1-CZ 3.14Å; F243-F256 HydrophobicContact CD1-CZ 3.14Å; F243-F256 HydrophobicContact CE1-CD1 4.21Å; F243-F256 AromaticContact CE1-CE1 3.21Å; F243-F256 HydrophobicContact CE1-CE1 3.21Å; F243-F256 AromaticContact CE1-CZ 3.82Å; F243-F256 HydrophobicContact CE1-CZ 3.82Å; F243-F256 HydrophobicContact CG-CE1 4.1Å; F243-F256 AromaticContact CG-CZ 3.88Å; F243-F256 HydrophobicContact CG-CZ 3.88Å; F243-F256 HydrophobicContact CZ-CE1 4.32Å; E244-F256 HydrophobicContact CB-CE2 4.48Å; E244-F256 HydrophobicContact CG-CD2 3.94Å; E244-F256 HydrophobicContact CG-CE2 3.34Å; E244-F256 HydrophobicContact CG-CZ 4.2Å; L247-F256 HydrophobicContact CD1-CD1 3.51Å; L247-F256 HydrophobicContact CD1-CD2 4.35Å; L247-F256 HydrophobicContact CD1-CE1 3.4Å; L247-F256 VanDerWaalsContact CD1-CE1 3.4Å; L247-F256 HydrophobicContact CD1-CE2 4.35Å; L247-F256 HydrophobicContact CD1-CG 3.97Å; L247-F256 HydrophobicContact CD1-CZ 3.86Å; L247-F256 HydrophobicContact CG-CE1 4.42Å; S254-F256 PolarHBondContact O-N 3.32Å; F256-F427 HydrophobicContact CB-CZ 4.36Å; F256-F427 HydrophobicContact CD1-CD2 4.36Å; F256-F427 AromaticContact CD1-CE2 3.88Å; F256-F427 HydrophobicContact CD1-CE2 3.88Å; F256-F427 HydrophobicContact CD1-CZ 4.41Å; F256-F427 WeakPolarHBondContact O-CE1 3.1Å; F256-F427 WeakPolarHBondContact O-CZ 3.34Å; F256-L430 HydrophobicContact CD1-CB 3.4Å; F256-L430 VanDerWaalsContact CD1-CB 3.4Å; F256-L430 HydrophobicContact CD1-CD1 4.4Å; F256-L430 HydrophobicContact CD2-CB 4.29Å; F256-L430 HydrophobicContact CE1-CB 2.96Å; F256-L430 HydrophobicContact CE1-CD1 3.34Å; F256-L430 HydrophobicContact CE1-CD2 4.32Å; F256-L430 HydrophobicContact CE1-CG 3.67Å; F256-L430 HydrophobicContact CE2-CB 3.87Å; F256-L430 HydrophobicContact CG-CB 4.06Å; F256-L430 HydrophobicContact CZ-CB 3.23Å; F256-L430 HydrophobicContact CZ-CD1 3.64Å; F256-L430 HydrophobicContact CZ-CD2 3.9Å; F256-L430 HydrophobicContact CZ-CG 3.77Å; F256-T431 HydrophobicContact CB-CG2 4.29Å; F256-T431 WeakPolarHBondContact O-CG2 3.32Å; F256-T431 PolarHBondContact O-OG1 3.11Å; F256-M434 HydrophobicContact CB-CG 4.27Å; F256-M434 HydrophobicContact CD2-CG 3.6Å; F256-M434 HydrophobicContact CD2-SD 4.42Å; F256-M434 HydrophobicContact CE2-CG 4.44Å; F256-M434 HydrophobicContact CG-CG 4.34Å
257E69.8Low69.3Low44 Ų4452.8 Ų52.821%0.20624%0.241CC..G310 helixtrans-90.5-28.8173.8-65.5-65.7-161.900111.3R110 S254 G255 R260 L261 R435R110-E257 IonicContact CZ-OE2 3.13Å; R110-E257 IonicContact NH1-OE2 3.82Å; R110-E257 PolarHBondContact NH1-OE2 2.93Å; R110-E257 IonicContact NH2-OE1 3.72Å; R110-E257 PolarHBondContact NH2-OE1 3.11Å; R110-E257 IonicContact NH2-OE2 2.64Å; R110-E257 PolarHBondContact NH2-OE2 2.61Å; S254-E257 PolarHBondContact O-N 3.2Å; G255-E257 PolarHBondContact O-N 2.84Å; G255-E257 VanDerWaalsContact O-N 3.12Å; E257-R260 VanDerWaalsContact CD-NH2 3.29Å; E257-R260 IonicContact OE1-NH2 3.34Å; E257-R260 PolarHBondContact OE1-NH2 2.91Å; E257-R260 IonicContact OE2-CZ 3.45Å; E257-R260 VanDerWaalsContact OE2-CZ 3.3Å; E257-R260 IonicContact OE2-NE 2.68Å; E257-R260 PolarHBondContact OE2-NE 2.94Å; E257-R260 VanDerWaalsContact OE2-NE 3.1Å; E257-R260 IonicContact OE2-NH2 2.83Å; E257-R260 PolarHBondContact OE2-NH2 3.42Å; E257-L261 WeakPolarHBondContact O-CB 3.43Å; E257-L261 PolarHBondContact O-N 3.36Å; E257-R435 IonicContact OE1-NE 3.79Å; E257-R435 PolarHBondContact OE1-NE 3.42Å
258E69.7Low70.8Confident35 Ų3553 Ų5316%0.16424%0.241CC..Hα-helixtrans-73.8-53.8-179.4-157.1155-17300112.6K116 Y252 R253 S254 G255 R260 L261 E262K116-E258 IonicContact NZ-OE1 2.82Å; K116-E258 PolarHBondContact NZ-OE1 3.16Å; Y252-E258 HydrophobicContact CD1-CB 3.87Å; Y252-E258 HydrophobicContact CD1-CG 3.93Å; R253-E258 PolarHBondContact N-OE2 3.4Å; R253-E258 VanDerWaalsContact N-OE2 3.1Å; S254-E258 PolarHBondContact N-OE2 3.22Å; S254-E258 VanDerWaalsContact OG-CB 3.23Å; S254-E258 WeakPolarHBondContact OG-CB 3.19Å; S254-E258 PolarHBondContact OG-OE2 3.37Å; G255-E258 PolarHBondContact O-N 3.21Å; G255-E258 VanDerWaalsContact O-N 3.13Å; E258-R260 PolarHBondContact O-N 3.36Å; E258-R260 VanDerWaalsContact O-N 3.13Å; E258-L261 WeakPolarHBondContact O-CB 3.2Å; E258-L261 PolarHBondContact O-N 3.08Å; E258-E262 WeakPolarHBondContact O-CB 3.13Å; E258-E262 PolarHBondContact O-N 2.83Å
259L66.5Low71.4Confident28 Ų2848 Ų4815%0.14722%0.223CC..Hα-helixtrans-64.7-20.6179.9167.265.6000110.6L247 Y252 G255 L263 F427L247-L259 HydrophobicContact CD2-CD2 3.51Å; Y252-L259 HydrophobicContact CD1-CB 3.66Å; Y252-L259 HydrophobicContact CD2-CB 4.43Å; Y252-L259 HydrophobicContact CE1-CB 3.54Å; Y252-L259 HydrophobicContact CE1-CD1 3.99Å; Y252-L259 HydrophobicContact CE1-CG 4.32Å; Y252-L259 HydrophobicContact CE2-CB 4.37Å; Y252-L259 HydrophobicContact CE2-CD1 4.28Å; Y252-L259 HydrophobicContact CE2-CD2 4.49Å; Y252-L259 HydrophobicContact CG-CB 4.09Å; Y252-L259 WeakPolarHBondContact OH-CD1 3.24Å; G255-L259 PolarHBondContact O-N 2.7Å; L259-L263 WeakPolarHBondContact O-CB 3.44Å; L259-L263 PolarHBondContact O-N 3.35Å; L259-F427 HydrophobicContact CB-CD2 3.87Å; L259-F427 HydrophobicContact CB-CE2 3.16Å; L259-F427 HydrophobicContact CB-CZ 3.63Å; L259-F427 HydrophobicContact CD1-CD2 4.5Å; L259-F427 HydrophobicContact CD2-CD2 3.09Å; L259-F427 HydrophobicContact CD2-CE2 3.26Å; L259-F427 HydrophobicContact CD2-CG 4.16Å; L259-F427 HydrophobicContact CD2-CZ 4.4Å; L259-F427 HydrophobicContact CG-CD2 3.21Å; L259-F427 HydrophobicContact CG-CE2 3.09Å; L259-F427 HydrophobicContact CG-CG 4.02Å; L259-F427 HydrophobicContact CG-CZ 3.83Å
260R70.2Confident71.8Confident4 Ų443.8 Ų43.82%0.01521%0.206CC..Hα-helixtrans-69.2-52.4178-163154.554.4148.8-32.7110.3R110 E257 E258 E262 L263 C264 A298 F300 F427 T431R110-R260 VanDerWaalsContact CZ-CZ 3.46Å; R110-R260 VanDerWaalsContact NH1-NH2 3.15Å; E257-R260 VanDerWaalsContact CD-NH2 3.29Å; E257-R260 IonicContact OE1-NH2 3.34Å; E257-R260 PolarHBondContact OE1-NH2 2.91Å; E257-R260 IonicContact OE2-CZ 3.45Å; E257-R260 VanDerWaalsContact OE2-CZ 3.3Å; E257-R260 IonicContact OE2-NE 2.68Å; E257-R260 PolarHBondContact OE2-NE 2.94Å; E257-R260 VanDerWaalsContact OE2-NE 3.1Å; E257-R260 IonicContact OE2-NH2 2.83Å; E257-R260 PolarHBondContact OE2-NH2 3.42Å; E258-R260 PolarHBondContact O-N 3.36Å; E258-R260 VanDerWaalsContact O-N 3.13Å; R260-E262 VanDerWaalsContact C-N 3.32Å; R260-L263 PolarHBondContact O-N 3.5Å; R260-C264 WeakPolarHBondContact O-CB 3.18Å; R260-C264 PolarHBondContact O-N 3.46Å; R260-A298 PolarHBondContact NH1-O 2.93Å; R260-F300 HydrophobicContact CG-CE2 3.89Å; R260-F300 HydrophobicContact CG-CZ 4.22Å; R260-F427 HydrophobicContact CB-CD1 4.13Å; R260-F427 HydrophobicContact CB-CE1 3.09Å; R260-F427 HydrophobicContact CB-CZ 3.56Å; R260-F427 HydrophobicContact CG-CD1 4.18Å; R260-F427 HydrophobicContact CG-CE1 3.5Å; R260-F427 VanDerWaalsContact CG-CE1 3.5Å; R260-F427 HydrophobicContact CG-CZ 4.44Å; R260-T431 VanDerWaalsContact NH2-CG2 3.29Å
261L77.7Confident73.1Confident22 Ų2238.9 Ų38.912%0.11518%0.181CC..Hα-helixtrans-63.1-46.7-178.8176.461.7000108.9Q113 K116 E257 E258 S265 F300Q113-L261 HydrophobicContact CB-CD1 4.08Å; Q113-L261 HydrophobicContact CB-CG 4.41Å; Q113-L261 HydrophobicContact CG-CD1 3.94Å; Q113-L261 HydrophobicContact CG-CD2 4.28Å; Q113-L261 HydrophobicContact CG-CG 4.49Å; K116-L261 HydrophobicContact CB-CG 4.33Å; K116-L261 HydrophobicContact CG-CD2 3.89Å; K116-L261 HydrophobicContact CG-CG 3.96Å; E257-L261 WeakPolarHBondContact O-CB 3.43Å; E257-L261 PolarHBondContact O-N 3.36Å; E258-L261 WeakPolarHBondContact O-CB 3.2Å; E258-L261 PolarHBondContact O-N 3.08Å; L261-S265 WeakPolarHBondContact O-CB 2.79Å; L261-S265 PolarHBondContact O-N 3.28Å; L261-S265 PolarHBondContact O-OG 3.48Å; L261-F300 HydrophobicContact CB-CZ 4.48Å; L261-F300 HydrophobicContact CD1-CE1 3.7Å; L261-F300 HydrophobicContact CD1-CZ 4.23Å
262E71.7Confident73.4Confident32 Ų3230.8 Ų30.815%0.1515%0.146CC..Hα-helixtrans-59.5-51.7174.7-179.5164.9156.200111.8W118 Y252 E258 R260 S265 N266W118-E262 PolarHBondContact NE1-OE1 2.84Å; Y252-E262 VanDerWaalsContact CE1-OE2 3.26Å; Y252-E262 WeakPolarHBondContact CE1-OE2 3.5Å; Y252-E262 PolarHBondContact OH-OE1 2.78Å; E258-E262 WeakPolarHBondContact O-CB 3.13Å; E258-E262 PolarHBondContact O-N 2.83Å; R260-E262 VanDerWaalsContact C-N 3.32Å; E262-S265 PolarHBondContact O-N 3.49Å; E262-N266 PolarHBondContact O-N 3.16Å; E262-N266 PolarHBondContact O-ND2 3.25Å
263L73.4Confident73.9Confident11 Ų1132.4 Ų32.46%0.05815%0.154CC..Hα-helixtrans-62.4-51.1-177.1-169.278.1000112.7L259 R260 S265 N266 L267 F420 A424L259-L263 WeakPolarHBondContact O-CB 3.44Å; L259-L263 PolarHBondContact O-N 3.35Å; R260-L263 PolarHBondContact O-N 3.5Å; L263-S265 VanDerWaalsContact C-N 3.3Å; L263-S265 PolarHBondContact O-N 3.01Å; L263-N266 PolarHBondContact O-N 3.14Å; L263-L267 HydrophobicContact CG-CD1 4.36Å; L263-L267 WeakPolarHBondContact O-CG 2.9Å; L263-L267 PolarHBondContact O-N 3.33Å; L263-F420 HydrophobicContact CD1-CD1 3.94Å; L263-F420 HydrophobicContact CD1-CE1 3.14Å; L263-F420 HydrophobicContact CD1-CE2 4.41Å; L263-F420 HydrophobicContact CD1-CZ 3.46Å; L263-F420 VanDerWaalsContact CD1-CZ 3.46Å; L263-F420 HydrophobicContact CD2-CE1 4.49Å; L263-F420 HydrophobicContact CG-CE1 3.71Å; L263-F420 HydrophobicContact CG-CZ 4.27Å; L263-A424 HydrophobicContact CD2-CB 3.3Å; L263-A424 HydrophobicContact CG-CB 4.45Å
264C81.1Confident73.8Confident5 Ų525 Ų253%0.03413%0.126CC..Hα-helixtrans-68.1-31.6179.2-77.60000112.1R260 N266 F268 C295 F300 F303R260-C264 WeakPolarHBondContact O-CB 3.18Å; R260-C264 PolarHBondContact O-N 3.46Å; C264-N266 VanDerWaalsContact C-N 3.33Å; C264-N266 PolarHBondContact O-N 2.7Å; C264-F268 WeakPolarHBondContact O-CB 3.37Å; C264-F268 PolarHBondContact O-N 2.97Å; C264-C295 WeakPolarHBondContact CA-SG 3.42Å; C264-C295 HydrophobicContact CB-CB 3.85Å; C264-C295 WeakPolarHBondContact CB-SG 3.44Å; C264-C295 VanDerWaalsContact SG-CA 3.58Å; C264-C295 WeakPolarHBondContact SG-CB 3.26Å; C264-C295 CovalentContact SG-SG 2.06Å; C264-C295 PolarHBondContact SG-SG 3.33Å; C264-F300 HydrophobicContact CB-CD1 4.19Å; C264-F300 HydrophobicContact CB-CD2 3.53Å; C264-F300 HydrophobicContact CB-CE1 4.19Å; C264-F300 HydrophobicContact CB-CE2 3.56Å; C264-F300 HydrophobicContact CB-CG 3.87Å; C264-F300 HydrophobicContact CB-CZ 3.9Å; C264-F303 HydrophobicContact CB-CE2 4.08Å; C264-F303 HydrophobicContact CB-CZ 4.5Å; C264-F303 VanDerWaalsContact O-CE2 3.27Å; C264-F303 WeakPolarHBondContact O-CE2 3.36Å; C264-F303 WeakPolarHBondContact O-CZ 3.39Å
265S81.1Confident73.7Confident0 Ų021.8 Ų21.80%010%0.104CC..Hα-helixtrans-62.3-42.6171.8-59.80000111.1Q113 L261 E262 L263 Y269Q113-S265 PolarHBondContact N-OG 2.84Å; Q113-S265 PolarHBondContact O-OG 3.26Å; L261-S265 WeakPolarHBondContact O-CB 2.79Å; L261-S265 PolarHBondContact O-N 3.28Å; L261-S265 PolarHBondContact O-OG 3.48Å; E262-S265 PolarHBondContact O-N 3.49Å; L263-S265 VanDerWaalsContact C-N 3.3Å; L263-S265 PolarHBondContact O-N 3.01Å; S265-Y269 WeakPolarHBondContact O-CD2 3.37Å
266N76.4Confident73.6Confident11 Ų1124.4 Ų24.46%0.05912%0.119CC..Hα-helixtrans-71.5-43.5178.2-75.4-73.4000113K116 W118 E262 L263 C264 F268 Y269 V270K116-N266 PolarHBondContact O-ND2 2.85Å; W118-N266 WeakPolarHBondContact CB-OD1 3.25Å; W118-N266 HydrophobicContact CD2-CB 4.2Å; W118-N266 HydrophobicContact CE3-CB 4.42Å; W118-N266 VanDerWaalsContact CG-CG 3.46Å; W118-N266 VanDerWaalsContact CG-OD1 3.27Å; W118-N266 PolarHBondContact N-ND2 3.37Å; W118-N266 PolarHBondContact N-OD1 3.46Å; W118-N266 PolarHBondContact NE1-ND2 2.93Å; E262-N266 PolarHBondContact O-N 3.16Å; E262-N266 PolarHBondContact O-ND2 3.25Å; L263-N266 PolarHBondContact O-N 3.14Å; C264-N266 VanDerWaalsContact C-N 3.33Å; C264-N266 PolarHBondContact O-N 2.7Å; N266-F268 PolarHBondContact O-N 3.35Å; N266-Y269 PolarHBondContact O-N 3.17Å; N266-V270 WeakPolarHBondContact O-CG2 3.18Å; N266-V270 PolarHBondContact O-N 3.28Å
267L79Confident73.6Confident4 Ų427.4 Ų27.42%0.02114%0.14CC..Hα-helixtrans-56.9-37.2175.8-80.8177.3000112.2L263 V270 M271 M291 F303 F420L263-L267 HydrophobicContact CG-CD1 4.36Å; L263-L267 WeakPolarHBondContact O-CG 2.9Å; L263-L267 PolarHBondContact O-N 3.33Å; L267-V270 PolarHBondContact O-N 2.94Å; L267-M271 VanDerWaalsContact O-CB 3.23Å; L267-M271 WeakPolarHBondContact O-CB 3.45Å; L267-M271 PolarHBondContact O-N 3.11Å; L267-M291 HydrophobicContact CD2-CE 3.83Å; L267-M291 HydrophobicContact CD2-CG 3.97Å; L267-M291 HydrophobicContact CD2-SD 3.93Å; L267-F303 HydrophobicContact CB-CE1 4.2Å; L267-F303 HydrophobicContact CB-CZ 3.8Å; L267-F420 HydrophobicContact CD1-CD1 4.3Å; L267-F420 HydrophobicContact CD1-CE1 3.81Å; L267-F420 HydrophobicContact CD2-CD1 3.51Å; L267-F420 HydrophobicContact CD2-CE1 3.17Å; L267-F420 HydrophobicContact CD2-CG 4.47Å; L267-F420 HydrophobicContact CD2-CZ 3.84Å; L267-F420 HydrophobicContact CG-CD1 4.03Å; L267-F420 HydrophobicContact CG-CE1 3.29Å; L267-F420 HydrophobicContact CG-CZ 3.96Å
268F83.6Confident73.2Confident7 Ų728.3 Ų28.33%0.03115%0.146CC..Hα-helixtrans-62.3-48.2179.4175.5-103.2000111.7I112 C264 N266 V270 M271 E272 E302 F303 R305 W308I112-F268 HydrophobicContact CD1-CB 3.19Å; I112-F268 HydrophobicContact CD1-CD1 3.55Å; I112-F268 HydrophobicContact CD1-CD2 3.36Å; I112-F268 HydrophobicContact CD1-CE1 4.16Å; I112-F268 HydrophobicContact CD1-CE2 4Å; I112-F268 HydrophobicContact CD1-CG 3.07Å; I112-F268 HydrophobicContact CD1-CZ 4.32Å; I112-F268 HydrophobicContact CG1-CB 4.45Å; I112-F268 HydrophobicContact CG2-CD1 4.5Å; C264-F268 WeakPolarHBondContact O-CB 3.37Å; C264-F268 PolarHBondContact O-N 2.97Å; N266-F268 PolarHBondContact O-N 3.35Å; F268-V270 VanDerWaalsContact C-N 3.31Å; F268-V270 PolarHBondContact O-N 2.75Å; F268-M271 HydrophobicContact CD2-CE 3.85Å; F268-M271 HydrophobicContact CE2-CE 4.46Å; F268-M271 PolarHBondContact O-N 3.43Å; F268-E272 WeakPolarHBondContact O-CB 3.39Å; F268-E272 PolarHBondContact O-N 2.79Å; F268-E302 HydrophobicContact CD2-CB 3.97Å; F268-E302 HydrophobicContact CE2-CB 3.48Å; F268-E302 VanDerWaalsContact CE2-CB 3.48Å; F268-E302 WeakPolarHBondContact CE2-O 3.47Å; F268-E302 HydrophobicContact CZ-CB 3.92Å; F268-F303 VanDerWaalsContact CA-CZ 3.47Å; F268-F303 HydrophobicContact CB-CE1 4.27Å; F268-F303 HydrophobicContact CB-CE2 3.7Å; F268-F303 HydrophobicContact CB-CZ 3.55Å; F268-F303 HydrophobicContact CD2-CD2 4.34Å; F268-F303 HydrophobicContact CD2-CE2 4.24Å; F268-F303 HydrophobicContact CD2-CZ 4.43Å; F268-F303 HydrophobicContact CG-CE2 4.44Å; F268-F303 VanDerWaalsContact N-CZ 3.3Å; F268-R305 VanDerWaalsContact CZ-CZ 3.47Å; F268-W308 HydrophobicContact CD2-CH2 4.19Å; F268-W308 AromaticContact CE2-CH2 3.74Å; F268-W308 HydrophobicContact CE2-CH2 3.74Å
269Y79.3Confident72.5Confident46 Ų4629.8 Ų29.818%0.1817%0.171CC..Hα-helixtrans-66.9-33.2178.1-67.9-66.4000112.5I112 A114 R117 S265 N266 H273I112-Y269 HydrophobicContact CG2-CE2 4.45Å; A114-Y269 WeakPolarHBondContact CB-OH 3.42Å; R117-Y269 HydrophobicContact CB-CE2 4.36Å; R117-Y269 HydrophobicContact CG-CD2 4.12Å; R117-Y269 HydrophobicContact CG-CE2 4.33Å; S265-Y269 WeakPolarHBondContact O-CD2 3.37Å; N266-Y269 PolarHBondContact O-N 3.17Å; Y269-H273 WeakPolarHBondContact O-CB 3.28Å; Y269-H273 PolarHBondContact O-N 2.82Å
270V74.2Confident71.9Confident47 Ų4729.2 Ų29.229%0.28517%0.171SC..Hα-helixtrans-64.7-48.2173.3171.80000110.8N266 L267 F268 H273 R274 M291N266-V270 WeakPolarHBondContact O-CG2 3.18Å; N266-V270 PolarHBondContact O-N 3.28Å; L267-V270 PolarHBondContact O-N 2.94Å; F268-V270 VanDerWaalsContact C-N 3.31Å; F268-V270 PolarHBondContact O-N 2.75Å; V270-H273 PolarHBondContact O-N 3.36Å; V270-R274 WeakPolarHBondContact O-CG 3.37Å; V270-R274 PolarHBondContact O-N 2.84Å; V270-M291 HydrophobicContact CG1-CE 4.23Å
271M77.7Confident71Confident0 Ų030.9 Ų30.90%018%0.182CC..Hα-helixtrans-67.6-45.8-179.8176-166.759.500111.4L267 F268 H273 R274 V275 A288 M291 Q292 F303 W308L267-M271 VanDerWaalsContact O-CB 3.23Å; L267-M271 WeakPolarHBondContact O-CB 3.45Å; L267-M271 PolarHBondContact O-N 3.11Å; F268-M271 HydrophobicContact CD2-CE 3.85Å; F268-M271 HydrophobicContact CE2-CE 4.46Å; F268-M271 PolarHBondContact O-N 3.43Å; M271-H273 VanDerWaalsContact C-N 3.31Å; M271-H273 PolarHBondContact O-N 3.36Å; M271-R274 WeakPolarHBondContact O-CB 3.2Å; M271-R274 PolarHBondContact O-N 2.85Å; M271-R274 VanDerWaalsContact O-N 3.1Å; M271-V275 HydrophobicContact CG-CG2 4.35Å; M271-V275 WeakPolarHBondContact O-CB 3.45Å; M271-V275 VanDerWaalsContact O-CG2 3.3Å; M271-V275 WeakPolarHBondContact O-CG2 3.31Å; M271-V275 PolarHBondContact O-N 3.38Å; M271-A288 HydrophobicContact CG-CB 4.34Å; M271-M291 HydrophobicContact CB-SD 4.01Å; M271-M291 HydrophobicContact SD-CB 4.35Å; M271-Q292 HydrophobicContact CE-CG 4.36Å; M271-Q292 HydrophobicContact SD-CB 4.42Å; M271-Q292 HydrophobicContact SD-CG 3.26Å; M271-Q292 WeakPolarHBondContact SD-CG 3.2Å; M271-F303 HydrophobicContact CE-CD1 3.3Å; M271-F303 HydrophobicContact CE-CE1 3.48Å; M271-F303 VanDerWaalsContact CE-CE1 3.48Å; M271-F303 HydrophobicContact CE-CG 4.19Å; M271-F303 HydrophobicContact CE-CZ 4.45Å; M271-F303 HydrophobicContact SD-CD1 3.68Å; M271-F303 HydrophobicContact SD-CE1 3.9Å; M271-W308 HydrophobicContact CE-CE3 4.23Å; M271-W308 HydrophobicContact CE-CH2 3.12Å; M271-W308 HydrophobicContact CE-CZ2 4.16Å; M271-W308 HydrophobicContact CE-CZ3 3.17Å; M271-W308 HydrophobicContact SD-CH2 4.28Å; M271-W308 HydrophobicContact SD-CZ3 3.97Å
272E77.6Confident69.9Low10 Ų1031.7 Ų31.75%0.04720%0.197CC..Hα-helixtrans-56.1-48.7175.1178.3168.6-120.900109.9F268 R274 V275 V276 R305 F367 G368F268-E272 WeakPolarHBondContact O-CB 3.39Å; F268-E272 PolarHBondContact O-N 2.79Å; E272-R274 PolarHBondContact O-N 2.68Å; E272-V275 PolarHBondContact O-N 3.27Å; E272-V276 HydrophobicContact CG-CG2 4.27Å; E272-V276 WeakPolarHBondContact O-CG2 3.23Å; E272-V276 PolarHBondContact O-N 2.79Å; E272-R305 IonicContact OE1-CZ 3.37Å; E272-R305 IonicContact OE1-NH1 3.19Å; E272-R305 PolarHBondContact OE1-NH1 3.06Å; E272-R305 IonicContact OE1-NH2 3.38Å; E272-R305 PolarHBondContact OE1-NH2 3.01Å; E272-F367 HydrophobicContact CG-CB 4.44Å; E272-F367 HydrophobicContact CG-CD1 4.07Å; E272-F367 WeakPolarHBondContact OE1-CA 3.5Å; E272-G368 PolarHBondContact OE1-N 2.71Å
273H70.8Confident69.5Low69 Ų6936.3 Ų36.332%0.31922%0.216SC..Hα-helixtrans-57.1-46.6174-178.7-79000111.8Y269 V270 M271 V275 V276 S277Y269-H273 WeakPolarHBondContact O-CB 3.28Å; Y269-H273 PolarHBondContact O-N 2.82Å; V270-H273 PolarHBondContact O-N 3.36Å; M271-H273 VanDerWaalsContact C-N 3.31Å; M271-H273 PolarHBondContact O-N 3.36Å; H273-V275 PolarHBondContact O-N 3.29Å; H273-V276 PolarHBondContact O-N 3.45Å; H273-S277 WeakPolarHBondContact O-CB 3.32Å; H273-S277 PolarHBondContact O-N 3.41Å; H273-S277 PolarHBondContact O-OG 2.77Å
274R69.4Low69.4Low76 Ų7636.2 Ų36.229%0.28722%0.215SC..Hα-helixtrans-60.3-43.4177.6-78.3-179.2171.9-127.70.7112.6V270 M271 E272 V276 S277 N278 D285V270-R274 WeakPolarHBondContact O-CG 3.37Å; V270-R274 PolarHBondContact O-N 2.84Å; M271-R274 WeakPolarHBondContact O-CB 3.2Å; M271-R274 PolarHBondContact O-N 2.85Å; M271-R274 VanDerWaalsContact O-N 3.1Å; E272-R274 PolarHBondContact O-N 2.68Å; R274-V276 VanDerWaalsContact C-N 3.34Å; R274-S277 PolarHBondContact O-OG 3.23Å; R274-N278 WeakPolarHBondContact O-CB 3.23Å; R274-N278 PolarHBondContact O-N 2.72Å; R274-N278 PolarHBondContact O-ND2 3.02Å; R274-D285 IonicContact NH1-OD1 3.64Å; R274-D285 IonicContact NH1-OD2 2.72Å; R274-D285 PolarHBondContact NH1-OD2 2.82Å
275V69Low69.3Low1 Ų137.8 Ų37.81%0.00622%0.223CC..Hα-helixtrans-64.4-40.4178.3167.60000110.8M271 E272 H273 G280 P281 Q284M271-V275 HydrophobicContact CG-CG2 4.35Å; M271-V275 WeakPolarHBondContact O-CB 3.45Å; M271-V275 VanDerWaalsContact O-CG2 3.3Å; M271-V275 WeakPolarHBondContact O-CG2 3.31Å; M271-V275 PolarHBondContact O-N 3.38Å; E272-V275 PolarHBondContact O-N 3.27Å; H273-V275 PolarHBondContact O-N 3.29Å; V275-G280 CarbonylContact O-C 3.56Å; V275-G280 WeakPolarHBondContact O-CA 3.33Å; V275-G280 PolarHBondContact O-N 3.27Å; V275-G280 VanDerWaalsContact O-N 3.15Å; V275-P281 HydrophobicContact CG1-CB 3.82Å; V275-Q284 HydrophobicContact CG2-CG 3.72Å
276V65.3Low69.2Low61 Ų6138.6 Ų38.637%0.3723%0.228SC..Hα-helixtrans-68.6-56.2175.1-177.30000110.5E272 H273 R274 N278 G279 G280 F367E272-V276 HydrophobicContact CG-CG2 4.27Å; E272-V276 WeakPolarHBondContact O-CG2 3.23Å; E272-V276 PolarHBondContact O-N 2.79Å; H273-V276 PolarHBondContact O-N 3.45Å; R274-V276 VanDerWaalsContact C-N 3.34Å; V276-N278 VanDerWaalsContact C-N 3.3Å; V276-N278 PolarHBondContact O-N 3.31Å; V276-G279 PolarHBondContact O-N 3.04Å; V276-G279 VanDerWaalsContact O-N 3.16Å; V276-G280 PolarHBondContact O-N 3.45Å; V276-F367 HydrophobicContact CB-CD1 4.4Å; V276-F367 HydrophobicContact CB-CE1 4.14Å; V276-F367 HydrophobicContact CB-CZ 4.29Å; V276-F367 HydrophobicContact CG1-CE2 4.33Å; V276-F367 HydrophobicContact CG1-CZ 4.35Å; V276-F367 HydrophobicContact CG2-CB 4.27Å; V276-F367 HydrophobicContact CG2-CD1 3.06Å; V276-F367 HydrophobicContact CG2-CD2 3.99Å; V276-F367 HydrophobicContact CG2-CE1 3.13Å; V276-F367 HydrophobicContact CG2-CE2 4.06Å; V276-F367 HydrophobicContact CG2-CG 3.5Å; V276-F367 VanDerWaalsContact CG2-CG 3.5Å; V276-F367 HydrophobicContact CG2-CZ 3.65Å
277S63Low69.2Low63 Ų6338.9 Ų38.944%0.44123%0.23SC..Hα-helixtrans-67.4-30.9-167.768.20000112.5H273 R274 G279H273-S277 WeakPolarHBondContact O-CB 3.32Å; H273-S277 PolarHBondContact O-N 3.41Å; H273-S277 PolarHBondContact O-OG 2.77Å; R274-S277 PolarHBondContact O-OG 3.23Å; S277-G279 PolarHBondContact O-N 2.69Å; S277-G279 VanDerWaalsContact O-N 3.12Å
278N60.4Low69.3Low62 Ų6238.8 Ų38.833%0.33223%0.229SC..THydrogen-bonded Turntrans-777.9179.8-66.8-9.1000113R274 V276 K283R274-N278 WeakPolarHBondContact O-CB 3.23Å; R274-N278 PolarHBondContact O-N 2.72Å; R274-N278 PolarHBondContact O-ND2 3.02Å; V276-N278 VanDerWaalsContact C-N 3.3Å; V276-N278 PolarHBondContact O-N 3.31Å; N278-K283 HydrophobicContact CB-CB 3.85Å; N278-K283 HydrophobicContact CB-CD 4.47Å; N278-K283 WeakPolarHBondContact O-CD 3.39Å; N278-K283 WeakPolarHBondContact O-CE 3.42Å; N278-K283 PolarHBondContact O-NZ 2.63Å
279G54.3Low69.4Low67 Ų6738.6 Ų38.669%0.69123%0.229SC*.THydrogen-bonded Turntrans89.630.917900000112.6V276 S277V276-G279 PolarHBondContact O-N 3.04Å; V276-G279 VanDerWaalsContact O-N 3.16Å; S277-G279 PolarHBondContact O-N 2.69Å; S277-G279 VanDerWaalsContact O-N 3.12Å
280G54.9Low69.5Low15 Ų1536.6 Ų36.616%0.15522%0.221CC..SBendtrans102.5175.4175.900000114.1V275 V276 G282 K283V275-G280 CarbonylContact O-C 3.56Å; V275-G280 WeakPolarHBondContact O-CA 3.33Å; V275-G280 PolarHBondContact O-N 3.27Å; V275-G280 VanDerWaalsContact O-N 3.15Å; V276-G280 PolarHBondContact O-N 3.45Å; G280-G282 PolarHBondContact O-N 2.71Å; G280-K283 PolarHBondContact O-N 2.66Å
281P50.3Low69.8Low39 Ų3934.5 Ų34.525%0.25321%0.208SC..G310 helixtrans-66.1-11.4-169.331.7-38.3000113.5V275 K283 P311V275-P281 HydrophobicContact CG1-CB 3.82Å; P281-K283 PolarHBondContact O-N 3.25Å; P281-K283 VanDerWaalsContact O-N 3.13Å; P281-P311 VanDerWaalsContact C-CB 3.4Å; P281-P311 VanDerWaalsContact C-CG 3.47Å; P281-P311 HydrophobicContact CB-CB 4.33Å; P281-P311 HydrophobicContact CB-CG 3.38Å; P281-P311 HydrophobicContact CG-CG 3.76Å; P281-P311 WeakPolarHBondContact O-CB 3.02Å; P281-P311 WeakPolarHBondContact O-CG 2.78Å
282G55.6Low70.3Confident40 Ų4034.5 Ų34.541%0.41221%0.208SC..G310 helixtrans-69.38.2171.100000117G280 H315G280-G282 PolarHBondContact O-N 2.71Å; G282-H315 PolarHBondContact O-CE1 3.38Å; G282-H315 PolarHBondContact O-NE2 3.38Å; G282-H315 VanDerWaalsContact O-NE2 3.12Å
283K62.9Low70.7Confident129 Ų12934.2 Ų34.256%0.56121%0.207SC*.G310 helixtrans-135.835.6174.4-60.4-162.2-155.8145.50113.1N278 G280 P281 D285N278-K283 HydrophobicContact CB-CB 3.85Å; N278-K283 HydrophobicContact CB-CD 4.47Å; N278-K283 WeakPolarHBondContact O-CD 3.39Å; N278-K283 WeakPolarHBondContact O-CE 3.42Å; N278-K283 PolarHBondContact O-NZ 2.63Å; G280-K283 PolarHBondContact O-N 2.66Å; P281-K283 PolarHBondContact O-N 3.25Å; P281-K283 VanDerWaalsContact O-N 3.13Å; K283-D285 PolarHBondContact O-N 3.43Å
284Q72Confident71.1Confident9 Ų931.6 Ų31.64%0.04220%0.196CC..  trans-66.6122.5171.5-73.5-179.811.900109.4V275 A288 W289 Q292V275-Q284 HydrophobicContact CG2-CG 3.72Å; Q284-A288 HydrophobicContact CB-CB 4.14Å; Q284-A288 HydrophobicContact CG-CB 4.23Å; Q284-W289 VanDerWaalsContact CB-NE1 3.32Å; Q284-W289 VanDerWaalsContact OE1-CD1 3.28Å; Q284-Q292 VanDerWaalsContact CD-NE2 3.27Å
285D78.2Confident71.9Confident37 Ų3728 Ų2820%0.19818%0.183CC..  trans-81.1167.3170.458.910.2000110.4R274 K283 L287 A288 W289 A325R274-D285 IonicContact NH1-OD1 3.64Å; R274-D285 IonicContact NH1-OD2 2.72Å; R274-D285 PolarHBondContact NH1-OD2 2.82Å; K283-D285 PolarHBondContact O-N 3.43Å; D285-L287 PolarHBondContact O-N 3.19Å; D285-L287 WeakPolarHBondContact OD1-CB 3.46Å; D285-A288 WeakPolarHBondContact O-CB 3.45Å; D285-A288 PolarHBondContact O-N 2.61Å; D285-A288 WeakPolarHBondContact OD1-CB 3.22Å; D285-A288 PolarHBondContact OD1-N 3.26Å; D285-W289 PolarHBondContact O-N 3.39Å; D285-A325 HydrophobicContact CB-CB 4Å
286T79.2Confident72.8Confident17 Ų1728.6 Ų28.610%0.10419%0.187CC..Hα-helixtrans-54.9-28.8177.9-48.50000112.2W289 L290 F340 A341 V344T286-W289 PolarHBondContact O-N 3.47Å; T286-L290 WeakPolarHBondContact O-CG 2.83Å; T286-L290 PolarHBondContact O-N 3.45Å; T286-F340 HydrophobicContact CG2-CD1 3.82Å; T286-F340 HydrophobicContact CG2-CE1 3.61Å; T286-A341 HydrophobicContact CG2-CB 4.06Å; T286-V344 HydrophobicContact CG2-CB 4.44Å; T286-V344 HydrophobicContact CG2-CG2 4.34Å
287L76Confident73.5Confident18 Ų1826.3 Ų26.39%0.09417%0.172CC..Hα-helixtrans-66.8-47.9175.6176.867.4000112.5D285 W289 L290 M291 L417 V421D285-L287 PolarHBondContact O-N 3.19Å; D285-L287 WeakPolarHBondContact OD1-CB 3.46Å; L287-W289 PolarHBondContact O-N 3.39Å; L287-L290 WeakPolarHBondContact O-CA 3.42Å; L287-L290 WeakPolarHBondContact O-CB 3.43Å; L287-L290 PolarHBondContact O-N 3.01Å; L287-M291 HydrophobicContact CD1-CE 3.99Å; L287-M291 HydrophobicContact CD2-CE 3.63Å; L287-M291 HydrophobicContact CG-CE 3.7Å; L287-M291 HydrophobicContact CG-SD 4.46Å; L287-M291 WeakPolarHBondContact O-CG 3.49Å; L287-M291 PolarHBondContact O-N 3.26Å; L287-L417 HydrophobicContact CB-CD2 4.31Å; L287-L417 HydrophobicContact CD1-CD1 3.69Å; L287-L417 HydrophobicContact CD1-CD2 3.38Å; L287-L417 HydrophobicContact CD1-CG 3.48Å; L287-L417 VanDerWaalsContact CD1-CG 3.48Å; L287-L417 HydrophobicContact CD2-CD1 3.54Å; L287-L417 HydrophobicContact CD2-CD2 3.07Å; L287-L417 HydrophobicContact CD2-CG 3.75Å; L287-L417 HydrophobicContact CG-CD1 4.05Å; L287-L417 HydrophobicContact CG-CD2 3.61Å; L287-L417 HydrophobicContact CG-CG 4.09Å; L287-V421 HydrophobicContact CD1-CG2 4.09Å
288A81.9Confident74.2Confident1 Ų123.5 Ų23.51%0.00815%0.153CC..Hα-helixtrans-56.1-40.1176.300000110.3M271 Q284 D285 M291 Q292M271-A288 HydrophobicContact CG-CB 4.34Å; Q284-A288 HydrophobicContact CB-CB 4.14Å; Q284-A288 HydrophobicContact CG-CB 4.23Å; D285-A288 WeakPolarHBondContact O-CB 3.45Å; D285-A288 PolarHBondContact O-N 2.61Å; D285-A288 WeakPolarHBondContact OD1-CB 3.22Å; D285-A288 PolarHBondContact OD1-N 3.26Å; A288-M291 PolarHBondContact O-N 2.99Å; A288-Q292 WeakPolarHBondContact O-CG 3.14Å; A288-Q292 PolarHBondContact O-N 3.44Å
289W85.5Confident75.2Confident4 Ų420.8 Ų20.82%0.01514%0.139CC..Hα-helixtrans-64.9-38.8174.3-58-22.1000113Q284 D285 T286 L287 M291 Q292 L293 L312 H315 Y322 A341 V344 A345 L348Q284-W289 VanDerWaalsContact CB-NE1 3.32Å; Q284-W289 VanDerWaalsContact OE1-CD1 3.28Å; D285-W289 PolarHBondContact O-N 3.39Å; T286-W289 PolarHBondContact O-N 3.47Å; L287-W289 PolarHBondContact O-N 3.39Å; W289-M291 VanDerWaalsContact C-N 3.34Å; W289-Q292 PolarHBondContact O-N 2.72Å; W289-L293 VanDerWaalsContact O-CB 3.29Å; W289-L293 WeakPolarHBondContact O-CB 3.39Å; W289-L293 PolarHBondContact O-N 3.08Å; W289-L312 HydrophobicContact CD2-CD1 4.09Å; W289-L312 HydrophobicContact CG-CD1 4.45Å; W289-L312 HydrophobicContact CZ2-CD1 3.99Å; W289-H315 HydrophobicContact CH2-CB 4.41Å; W289-H315 HydrophobicContact CZ2-CB 4.26Å; W289-Y322 AromaticContact CH2-CD1 3.57Å; W289-Y322 HydrophobicContact CH2-CD1 3.57Å; W289-Y322 HydrophobicContact CH2-CE1 4.25Å; W289-Y322 HydrophobicContact CH2-CG 4.33Å; W289-Y322 HydrophobicContact CZ2-CD1 4.37Å; W289-Y322 AromaticContact CZ3-CD1 3.93Å; W289-Y322 HydrophobicContact CZ3-CD1 3.93Å; W289-Y322 HydrophobicContact CZ3-CG 4.27Å; W289-A341 HydrophobicContact CZ3-CB 4.22Å; W289-V344 HydrophobicContact CB-CG1 3.65Å; W289-A345 HydrophobicContact CE3-CB 4.2Å; W289-A345 HydrophobicContact CZ3-CB 4.26Å; W289-L348 HydrophobicContact CB-CD2 3.96Å; W289-L348 HydrophobicContact CG-CD2 4.15Å
290L80.6Confident76.7Confident4 Ų417.6 Ų17.62%0.02111%0.106CC..Hα-helixtrans-63.3-39.4173.7-77.6168.5000112.4M200 T286 L287 S294 F340 V344M200-L290 HydrophobicContact CE-CD1 3.42Å; M200-L290 VanDerWaalsContact CE-CD1 3.42Å; T286-L290 WeakPolarHBondContact O-CG 2.83Å; T286-L290 PolarHBondContact O-N 3.45Å; L287-L290 WeakPolarHBondContact O-CA 3.42Å; L287-L290 WeakPolarHBondContact O-CB 3.43Å; L287-L290 PolarHBondContact O-N 3.01Å; L290-S294 VanDerWaalsContact O-CB 3.24Å; L290-S294 WeakPolarHBondContact O-CB 3.47Å; L290-S294 PolarHBondContact O-N 3.47Å; L290-S294 PolarHBondContact O-OG 3.4Å; L290-F340 HydrophobicContact CD1-CE1 4.03Å; L290-F340 HydrophobicContact CD1-CZ 3.94Å; L290-F340 HydrophobicContact CD2-CZ 4.09Å; L290-F340 HydrophobicContact CG-CZ 4.43Å; L290-V344 HydrophobicContact CD2-CB 4.41Å; L290-V344 HydrophobicContact CD2-CG1 3.91Å; L290-V344 HydrophobicContact CD2-CG2 3.53Å; L290-V344 HydrophobicContact CG-CG1 3.94Å; L290-V344 HydrophobicContact CG-CG2 4.02Å
291M80.8Confident78.3Confident3 Ų320.3 Ų20.32%0.01511%0.114CC..Hα-helixtrans-64.3-46.2174.7-66.2176.817900110.6L267 V270 M271 L287 A288 W289 S294 C295 F303 L417L267-M291 HydrophobicContact CD2-CE 3.83Å; L267-M291 HydrophobicContact CD2-CG 3.97Å; L267-M291 HydrophobicContact CD2-SD 3.93Å; V270-M291 HydrophobicContact CG1-CE 4.23Å; M271-M291 HydrophobicContact CB-SD 4.01Å; M271-M291 HydrophobicContact SD-CB 4.35Å; L287-M291 HydrophobicContact CD1-CE 3.99Å; L287-M291 HydrophobicContact CD2-CE 3.63Å; L287-M291 HydrophobicContact CG-CE 3.7Å; L287-M291 HydrophobicContact CG-SD 4.46Å; L287-M291 WeakPolarHBondContact O-CG 3.49Å; L287-M291 PolarHBondContact O-N 3.26Å; A288-M291 PolarHBondContact O-N 2.99Å; W289-M291 VanDerWaalsContact C-N 3.34Å; M291-S294 PolarHBondContact O-N 2.96Å; M291-C295 PolarHBondContact O-N 2.81Å; M291-F303 HydrophobicContact CB-CE1 4.34Å; M291-L417 HydrophobicContact CE-CD1 3.64Å
292Q87.9Confident80.2Confident0 Ų019.5 Ų19.50%011%0.106CC..Hα-helixtrans-56.8-53.9174-71.1-18046.400111.6M271 Q284 A288 W289 S294 S296 F303 W308 L348 Y352M271-Q292 HydrophobicContact CE-CG 4.36Å; M271-Q292 HydrophobicContact SD-CB 4.42Å; M271-Q292 HydrophobicContact SD-CG 3.26Å; M271-Q292 WeakPolarHBondContact SD-CG 3.2Å; Q284-Q292 VanDerWaalsContact CD-NE2 3.27Å; A288-Q292 WeakPolarHBondContact O-CG 3.14Å; A288-Q292 PolarHBondContact O-N 3.44Å; W289-Q292 PolarHBondContact O-N 2.72Å; Q292-S294 PolarHBondContact O-N 3.16Å; Q292-S296 WeakPolarHBondContact O-CB 3.36Å; Q292-S296 PolarHBondContact O-N 3.43Å; Q292-S296 PolarHBondContact O-OG 3.45Å; Q292-F303 HydrophobicContact CG-CD1 4.42Å; Q292-F303 WeakPolarHBondContact CG-O 2.99Å; Q292-W308 HydrophobicContact CG-CE3 4.31Å; Q292-W308 HydrophobicContact CG-CZ3 4.47Å; Q292-L348 HydrophobicContact CB-CD1 3.67Å; Q292-L348 HydrophobicContact CB-CD2 3.97Å; Q292-Y352 PolarHBondContact OE1-OH 3Å
293L86.6Confident81.9Confident4 Ų417.6 Ų17.62%0.0219%0.087CC..Hα-helixtrans-57.4-50.3-179.7176.660.5000111.1F40 W289 C295 S296 H297 V344 A347F40-L293 HydrophobicContact CE1-CD1 4.29Å; W289-L293 VanDerWaalsContact O-CB 3.29Å; W289-L293 WeakPolarHBondContact O-CB 3.39Å; W289-L293 PolarHBondContact O-N 3.08Å; L293-C295 PolarHBondContact O-N 3.32Å; L293-S296 PolarHBondContact O-OG 3.49Å; L293-H297 WeakPolarHBondContact O-CB 3.42Å; L293-H297 PolarHBondContact O-N 3.41Å; L293-V344 HydrophobicContact CD2-CG1 4.42Å; L293-A347 HydrophobicContact CD1-CB 3.72Å; L293-A347 HydrophobicContact CD2-CB 3.7Å; L293-A347 HydrophobicContact CG-CB 4.37Å
294S80.4Confident83.3Confident14 Ų1412 Ų1210%0.0986%0.063CC..Hα-helixtrans-62.7-47.6-175-58.70000112.1L290 M291 Q292 A298L290-S294 VanDerWaalsContact O-CB 3.24Å; L290-S294 WeakPolarHBondContact O-CB 3.47Å; L290-S294 PolarHBondContact O-N 3.47Å; L290-S294 PolarHBondContact O-OG 3.4Å; M291-S294 PolarHBondContact O-N 2.96Å; Q292-S294 PolarHBondContact O-N 3.16Å; S294-A298 WeakPolarHBondContact O-CB 3.27Å; S294-A298 PolarHBondContact O-N 2.66Å
295C85.5Confident84.1Confident1 Ų112 Ų121%0.0076%0.062CC..Hα-helixtrans-83.3-31.3-175.7-75.20000113.4C264 M291 L293 A298 S299 F300 F303C264-C295 WeakPolarHBondContact CA-SG 3.42Å; C264-C295 HydrophobicContact CB-CB 3.85Å; C264-C295 WeakPolarHBondContact CB-SG 3.44Å; C264-C295 VanDerWaalsContact SG-CA 3.58Å; C264-C295 WeakPolarHBondContact SG-CB 3.26Å; C264-C295 CovalentContact SG-SG 2.06Å; C264-C295 PolarHBondContact SG-SG 3.33Å; M291-C295 PolarHBondContact O-N 2.81Å; L293-C295 PolarHBondContact O-N 3.32Å; C295-A298 CarbonylContact O-C 3.53Å; C295-A298 VanDerWaalsContact O-C 3.27Å; C295-A298 WeakPolarHBondContact O-CA 3.47Å; C295-A298 WeakPolarHBondContact O-CB 3.47Å; C295-A298 PolarHBondContact O-N 2.99Å; C295-A298 VanDerWaalsContact O-N 3.11Å; C295-S299 PolarHBondContact O-N 3.21Å; C295-F300 HydrophobicContact CB-CB 4.44Å; C295-F300 HydrophobicContact CB-CD2 4.38Å; C295-F300 WeakPolarHBondContact O-CB 3.45Å; C295-F300 WeakPolarHBondContact O-CD2 3.28Å; C295-F300 PolarHBondContact O-N 2.84Å; C295-F303 HydrophobicContact CB-CB 4.38Å; C295-F303 HydrophobicContact CB-CD1 3.84Å; C295-F303 HydrophobicContact CB-CD2 3.29Å; C295-F303 HydrophobicContact CB-CE1 3.76Å; C295-F303 HydrophobicContact CB-CE2 3.2Å; C295-F303 HydrophobicContact CB-CG 3.57Å; C295-F303 HydrophobicContact CB-CZ 3.41Å; C295-F303 VanDerWaalsContact CB-CZ 3.41Å
296S87Confident84.7Confident13 Ų1311.3 Ų11.39%0.0916%0.059CC..Hα-helixtrans-65.1-43170.864.80000111.6Q292 L293 A298 S299 L304Q292-S296 WeakPolarHBondContact O-CB 3.36Å; Q292-S296 PolarHBondContact O-N 3.43Å; Q292-S296 PolarHBondContact O-OG 3.45Å; L293-S296 PolarHBondContact O-OG 3.49Å; S296-A298 PolarHBondContact O-N 3.24Å; S296-S299 VanDerWaalsContact O-CA 3.32Å; S296-S299 WeakPolarHBondContact O-CA 3.27Å; S296-S299 PolarHBondContact O-N 2.96Å; S296-L304 VanDerWaalsContact CB-CG 3.42Å
297H80.2Confident85Confident12 Ų1212.6 Ų12.66%0.0567%0.068CC..Hα-helixtrans-61.5-34.9170.8-172.1-34000110.5F40 Y105 L293 S299 F428F40-H297 AromaticContact CD2-CD2 3.98Å; F40-H297 AromaticContact CD2-NE2 3.84Å; F40-H297 AromaticContact CE2-CD2 3.2Å; F40-H297 WeakPolarHBondContact CE2-CD2 2.9Å; F40-H297 AromaticContact CE2-NE2 3.28Å; F40-H297 VanDerWaalsContact CE2-NE2 3.28Å; F40-H297 WeakPolarHBondContact CE2-NE2 3.12Å; F40-H297 AromaticContact CZ-CD2 3.7Å; Y105-H297 AromaticContact CD1-CE1 2.95Å; Y105-H297 WeakPolarHBondContact CD1-CE1 3.39Å; Y105-H297 AromaticContact CD1-ND1 3.15Å; Y105-H297 WeakPolarHBondContact CD1-ND1 3.06Å; Y105-H297 AromaticContact CE1-CE1 3.48Å; Y105-H297 VanDerWaalsContact CE1-CE1 3.48Å; Y105-H297 WeakPolarHBondContact CE1-CE1 3.41Å; Y105-H297 AromaticContact CE1-ND1 3.32Å; Y105-H297 VanDerWaalsContact CE1-ND1 3.32Å; Y105-H297 WeakPolarHBondContact CE1-ND1 3.49Å; Y105-H297 VanDerWaalsContact CE1-O 3.27Å; Y105-H297 WeakPolarHBondContact CE1-O 3.11Å; Y105-H297 AromaticContact CG-CE1 3.62Å; L293-H297 WeakPolarHBondContact O-CB 3.42Å; L293-H297 PolarHBondContact O-N 3.41Å; H297-S299 PolarHBondContact O-N 3.47Å; H297-S299 VanDerWaalsContact O-N 3.12Å; H297-F428 AromaticContact CE1-CZ 3.31Å; H297-F428 WeakPolarHBondContact CE1-CZ 3.31Å; H297-F428 AromaticContact ND1-CE2 3.79Å; H297-F428 AromaticContact ND1-CZ 3.39Å; H297-F428 WeakPolarHBondContact ND1-CZ 3.49Å; H297-F428 AromaticContact NE2-CZ 3.99Å
298A77.6Confident85.6Confident4 Ų411.9 Ų11.93%0.0336%0.064CC..THydrogen-bonded Turntrans-74.913.6170.800000114.8R260 S294 C295 S296 F300 F428R260-A298 PolarHBondContact NH1-O 2.93Å; S294-A298 WeakPolarHBondContact O-CB 3.27Å; S294-A298 PolarHBondContact O-N 2.66Å; C295-A298 CarbonylContact O-C 3.53Å; C295-A298 VanDerWaalsContact O-C 3.27Å; C295-A298 WeakPolarHBondContact O-CA 3.47Å; C295-A298 WeakPolarHBondContact O-CB 3.47Å; C295-A298 PolarHBondContact O-N 2.99Å; C295-A298 VanDerWaalsContact O-N 3.11Å; S296-A298 PolarHBondContact O-N 3.24Å; A298-F300 HydrophobicContact CB-CD2 4.01Å; A298-F300 HydrophobicContact CB-CE2 4.08Å; A298-F300 WeakPolarHBondContact O-CD2 3.47Å; A298-F300 WeakPolarHBondContact O-CE2 3.36Å; A298-F428 HydrophobicContact CB-CD2 4.35Å; A298-F428 HydrophobicContact CB-CE2 4.43Å
299S82.3Confident86.1Confident6 Ų611.8 Ų11.84%0.0426%0.064CC..THydrogen-bonded Turntrans77.48.9175.1-14.90000117.1P107 N108 R109 R110 C295 S296 H297 K301P107-S299 WeakPolarHBondContact CB-OG 3.49Å; P107-S299 WeakPolarHBondContact CG-OG 3.15Å; N108-S299 WeakPolarHBondContact O-CB 3.38Å; N108-S299 PolarHBondContact O-OG 3.47Å; R109-S299 CarbonylContact C-O 3.43Å; R110-S299 PolarHBondContact N-O 3.12Å; C295-S299 PolarHBondContact O-N 3.21Å; S296-S299 VanDerWaalsContact O-CA 3.32Å; S296-S299 WeakPolarHBondContact O-CA 3.27Å; S296-S299 PolarHBondContact O-N 2.96Å; H297-S299 PolarHBondContact O-N 3.47Å; H297-S299 VanDerWaalsContact O-N 3.12Å; S299-K301 PolarHBondContact O-N 3.48Å
300F86.5Confident86.3Confident0 Ų014 Ų140%08%0.079CC..BIsolated β-bridgetrans-81105.9177.2-65.2-88.4000109.6R110 I112 R260 L261 C264 C295 A298 E302 F303R110-F300 HydrophobicContact CB-CD1 4.1Å; R110-F300 HydrophobicContact CB-CE1 4.04Å; R110-F300 HydrophobicContact CB-CZ 4.43Å; R110-F300 WeakPolarHBondContact O-CA 3.22Å; I112-F300 HydrophobicContact CG1-CB 4.45Å; I112-F300 HydrophobicContact CG1-CD1 3.82Å; I112-F300 HydrophobicContact CG1-CG 4.49Å; R260-F300 HydrophobicContact CG-CE2 3.89Å; R260-F300 HydrophobicContact CG-CZ 4.22Å; L261-F300 HydrophobicContact CB-CZ 4.48Å; L261-F300 HydrophobicContact CD1-CE1 3.7Å; L261-F300 HydrophobicContact CD1-CZ 4.23Å; C264-F300 HydrophobicContact CB-CD1 4.19Å; C264-F300 HydrophobicContact CB-CD2 3.53Å; C264-F300 HydrophobicContact CB-CE1 4.19Å; C264-F300 HydrophobicContact CB-CE2 3.56Å; C264-F300 HydrophobicContact CB-CG 3.87Å; C264-F300 HydrophobicContact CB-CZ 3.9Å; C295-F300 HydrophobicContact CB-CB 4.44Å; C295-F300 HydrophobicContact CB-CD2 4.38Å; C295-F300 WeakPolarHBondContact O-CB 3.45Å; C295-F300 WeakPolarHBondContact O-CD2 3.28Å; C295-F300 PolarHBondContact O-N 2.84Å; A298-F300 HydrophobicContact CB-CD2 4.01Å; A298-F300 HydrophobicContact CB-CE2 4.08Å; A298-F300 WeakPolarHBondContact O-CD2 3.47Å; A298-F300 WeakPolarHBondContact O-CE2 3.36Å; F300-E302 PolarHBondContact O-N 3.38Å; F300-F303 HydrophobicContact CB-CD2 3.69Å; F300-F303 HydrophobicContact CB-CE2 4.15Å; F300-F303 PolarHBondContact O-N 3.37Å
301K88.6Confident86.6Confident72 Ų7214.4 Ų14.431%0.3138%0.081SC..G310 helixtrans-66.5-27.3-172.966-179.9-176.7173.40112.9R110 S111 S299 F303 L304R110-K301 PolarHBondContact O-N 3.12Å; S111-K301 VanDerWaalsContact OG-CE 3.24Å; S111-K301 WeakPolarHBondContact OG-CE 3.37Å; S299-K301 PolarHBondContact O-N 3.48Å; K301-F303 PolarHBondContact O-N 3.25Å; K301-F303 VanDerWaalsContact O-N 3.16Å; K301-L304 PolarHBondContact O-N 3.17Å
302E89.6Confident87.2Confident22 Ų2214.2 Ų14.210%0.1038%0.08CC..G310 helixtrans-63.7-20179.6-60.783.2174.400112.3S111 I112 F268 F300 L304 R305 W308 D362S111-E302 WeakPolarHBondContact CA-OE1 3.39Å; S111-E302 WeakPolarHBondContact CB-OE1 3.07Å; S111-E302 PolarHBondContact OG-OE1 3.07Å; I112-E302 HydrophobicContact CB-CG 4.4Å; I112-E302 HydrophobicContact CD1-CB 3.62Å; I112-E302 HydrophobicContact CD1-CG 4.02Å; I112-E302 HydrophobicContact CG1-CB 4.28Å; I112-E302 HydrophobicContact CG1-CG 4.27Å; I112-E302 VanDerWaalsContact N-CD 3.35Å; I112-E302 PolarHBondContact N-OE1 2.85Å; I112-E302 PolarHBondContact N-OE2 2.96Å; F268-E302 HydrophobicContact CD2-CB 3.97Å; F268-E302 HydrophobicContact CE2-CB 3.48Å; F268-E302 VanDerWaalsContact CE2-CB 3.48Å; F268-E302 WeakPolarHBondContact CE2-O 3.47Å; F268-E302 HydrophobicContact CZ-CB 3.92Å; F300-E302 PolarHBondContact O-N 3.38Å; E302-L304 PolarHBondContact O-N 3.18Å; E302-R305 WeakPolarHBondContact O-CG 3.39Å; E302-W308 WeakPolarHBondContact O-CZ3 2.91Å; E302-D362 WeakPolarHBondContact CA-OD2 3.35Å
303F91Very high87.4Confident0 Ų015.6 Ų15.60%09%0.087CC..G310 helixtrans-77-6.5173.5-78-91.5000114I112 C264 L267 F268 M271 M291 Q292 C295 F300 K301I112-F303 HydrophobicContact CD1-CD2 4.2Å; I112-F303 HydrophobicContact CD1-CE2 3.83Å; I112-F303 HydrophobicContact CG1-CE2 4.49Å; C264-F303 HydrophobicContact CB-CE2 4.08Å; C264-F303 HydrophobicContact CB-CZ 4.5Å; C264-F303 VanDerWaalsContact O-CE2 3.27Å; C264-F303 WeakPolarHBondContact O-CE2 3.36Å; C264-F303 WeakPolarHBondContact O-CZ 3.39Å; L267-F303 HydrophobicContact CB-CE1 4.2Å; L267-F303 HydrophobicContact CB-CZ 3.8Å; F268-F303 VanDerWaalsContact CA-CZ 3.47Å; F268-F303 HydrophobicContact CB-CE1 4.27Å; F268-F303 HydrophobicContact CB-CE2 3.7Å; F268-F303 HydrophobicContact CB-CZ 3.55Å; F268-F303 HydrophobicContact CD2-CD2 4.34Å; F268-F303 HydrophobicContact CD2-CE2 4.24Å; F268-F303 HydrophobicContact CD2-CZ 4.43Å; F268-F303 HydrophobicContact CG-CE2 4.44Å; F268-F303 VanDerWaalsContact N-CZ 3.3Å; M271-F303 HydrophobicContact CE-CD1 3.3Å; M271-F303 HydrophobicContact CE-CE1 3.48Å; M271-F303 VanDerWaalsContact CE-CE1 3.48Å; M271-F303 HydrophobicContact CE-CG 4.19Å; M271-F303 HydrophobicContact CE-CZ 4.45Å; M271-F303 HydrophobicContact SD-CD1 3.68Å; M271-F303 HydrophobicContact SD-CE1 3.9Å; M291-F303 HydrophobicContact CB-CE1 4.34Å; Q292-F303 HydrophobicContact CG-CD1 4.42Å; Q292-F303 WeakPolarHBondContact CG-O 2.99Å; C295-F303 HydrophobicContact CB-CB 4.38Å; C295-F303 HydrophobicContact CB-CD1 3.84Å; C295-F303 HydrophobicContact CB-CD2 3.29Å; C295-F303 HydrophobicContact CB-CE1 3.76Å; C295-F303 HydrophobicContact CB-CE2 3.2Å; C295-F303 HydrophobicContact CB-CG 3.57Å; C295-F303 HydrophobicContact CB-CZ 3.41Å; C295-F303 VanDerWaalsContact CB-CZ 3.41Å; F300-F303 HydrophobicContact CB-CD2 3.69Å; F300-F303 HydrophobicContact CB-CE2 4.15Å; F300-F303 PolarHBondContact O-N 3.37Å; K301-F303 PolarHBondContact O-N 3.25Å; K301-F303 VanDerWaalsContact O-N 3.16Å
304L91.3Very high87.6Confident10 Ų1021.7 Ų21.75%0.05212%0.12CC..G310 helixtrans-118.851.1176.6-60177.4000110.5S296 K301 E302 L348 C351 Y352 C355 D362S296-L304 VanDerWaalsContact CB-CG 3.42Å; K301-L304 PolarHBondContact O-N 3.17Å; E302-L304 PolarHBondContact O-N 3.18Å; L304-L348 HydrophobicContact CD2-CD1 3.86Å; L304-C351 HydrophobicContact CD1-CB 4.05Å; L304-C351 HydrophobicContact CD2-CB 3.81Å; L304-Y352 HydrophobicContact CB-CD1 4.36Å; L304-Y352 HydrophobicContact CB-CE1 4Å; L304-Y352 HydrophobicContact CD2-CD1 4.29Å; L304-Y352 HydrophobicContact CD2-CD2 4.12Å; L304-Y352 HydrophobicContact CD2-CE1 4.14Å; L304-Y352 HydrophobicContact CD2-CE2 3.95Å; L304-Y352 HydrophobicContact CD2-CG 4.28Å; L304-C355 HydrophobicContact CB-CB 4.5Å; L304-C355 HydrophobicContact CD1-CB 3.76Å; L304-D362 PolarHBondContact O-N 3.23Å
305R90.4Very high88.1Confident11 Ų1123.9 Ų23.94%0.04213%0.128CC..BIsolated β-bridgetrans-65.8132.4173.2-82.8173.2172.5179.2-8.5110.9F268 E272 E302 S307 W308 Y352 D362 G366F268-R305 VanDerWaalsContact CZ-CZ 3.47Å; E272-R305 IonicContact OE1-CZ 3.37Å; E272-R305 IonicContact OE1-NH1 3.19Å; E272-R305 PolarHBondContact OE1-NH1 3.06Å; E272-R305 IonicContact OE1-NH2 3.38Å; E272-R305 PolarHBondContact OE1-NH2 3.01Å; E302-R305 WeakPolarHBondContact O-CG 3.39Å; R305-S307 PolarHBondContact O-N 3.44Å; R305-W308 HydrophobicContact CB-CD2 3.82Å; R305-W308 HydrophobicContact CB-CE3 3.9Å; R305-W308 HydrophobicContact CB-CG 4.16Å; R305-W308 HydrophobicContact CB-CZ3 4.24Å; R305-W308 HydrophobicContact CG-CH2 4.43Å; R305-W308 HydrophobicContact CG-CZ3 4.41Å; R305-W308 PolarHBondContact O-N 3.45Å; R305-Y352 PolarHBondContact O-OH 3.41Å; R305-D362 WeakPolarHBondContact CA-O 3.35Å; R305-D362 HydrophobicContact CG-CB 3.81Å; R305-D362 VanDerWaalsContact CG-OD2 3.31Å; R305-D362 WeakPolarHBondContact CG-OD2 3.26Å; R305-D362 IonicContact NE-OD2 2.9Å; R305-D362 PolarHBondContact NE-OD2 3.41Å; R305-G366 PolarHBondContact NH1-O 2.71Å; R305-G366 PolarHBondContact NH2-O 3.34Å
306L89.2Confident88.5Confident22 Ų2225.7 Ų25.712%0.11514%0.137CC..G310 helixtrans-60.3-31.7179-71.9-176.6000112.6L8 W308 L309 P310 L356 C361 D362 T363L8-L306 HydrophobicContact CD1-CD2 4.46Å; L306-W308 PolarHBondContact O-N 2.92Å; L306-L309 PolarHBondContact O-N 3.22Å; L306-P310 WeakPolarHBondContact O-CD 3.4Å; L306-L356 HydrophobicContact CD2-CD2 3.62Å; L306-L356 HydrophobicContact CD2-CG 4.47Å; L306-C361 HydrophobicContact CD1-CB 4.18Å; L306-C361 HydrophobicContact CD2-CB 3.39Å; L306-C361 HydrophobicContact CG-CB 3.54Å; L306-D362 PolarHBondContact N-O 2.93Å; L306-T363 HydrophobicContact CD1-CG2 3.9Å
307S86.9Confident88.8Confident43 Ų4328.4 Ų28.430%0.30115%0.148SC..G310 helixtrans-66.1-14.217757.40000114.2R305R305-S307 PolarHBondContact O-N 3.44Å
308W88.7Confident89.4Confident3 Ų333.6 Ų33.61%0.01118%0.183CC..G310 helixtrans-96.6-16.5177.9-63.4-11.3000113.9F268 M271 Q292 E302 R305 L306 P311 L312F268-W308 HydrophobicContact CD2-CH2 4.19Å; F268-W308 AromaticContact CE2-CH2 3.74Å; F268-W308 HydrophobicContact CE2-CH2 3.74Å; M271-W308 HydrophobicContact CE-CE3 4.23Å; M271-W308 HydrophobicContact CE-CH2 3.12Å; M271-W308 HydrophobicContact CE-CZ2 4.16Å; M271-W308 HydrophobicContact CE-CZ3 3.17Å; M271-W308 HydrophobicContact SD-CH2 4.28Å; M271-W308 HydrophobicContact SD-CZ3 3.97Å; Q292-W308 HydrophobicContact CG-CE3 4.31Å; Q292-W308 HydrophobicContact CG-CZ3 4.47Å; E302-W308 WeakPolarHBondContact O-CZ3 2.91Å; R305-W308 HydrophobicContact CB-CD2 3.82Å; R305-W308 HydrophobicContact CB-CE3 3.9Å; R305-W308 HydrophobicContact CB-CG 4.16Å; R305-W308 HydrophobicContact CB-CZ3 4.24Å; R305-W308 HydrophobicContact CG-CH2 4.43Å; R305-W308 HydrophobicContact CG-CZ3 4.41Å; R305-W308 PolarHBondContact O-N 3.45Å; L306-W308 PolarHBondContact O-N 2.92Å; W308-P311 WeakPolarHBondContact O-CD 3.4Å; W308-P311 WeakPolarHBondContact O-CG 3.48Å; W308-L312 PolarHBondContact O-N 2.83Å
309L91.5Very high90.3Very high0 Ų036.8 Ų36.80%020%0.202CC..Hα-helixtrans-68.2-48178.917562.3000113L8 T12 L306 L312 L313 L349 Y352 L356L8-L309 HydrophobicContact CD2-CD2 4.34Å; T12-L309 HydrophobicContact CG2-CD1 4.34Å; L306-L309 PolarHBondContact O-N 3.22Å; L309-L312 HydrophobicContact CD1-CD2 4.41Å; L309-L312 WeakPolarHBondContact O-CA 3.1Å; L309-L312 WeakPolarHBondContact O-CB 3.49Å; L309-L312 PolarHBondContact O-N 3.24Å; L309-L313 HydrophobicContact CD1-CD1 4.1Å; L309-L313 HydrophobicContact CD1-CD2 4.15Å; L309-L313 HydrophobicContact CD1-CG 3.89Å; L309-L313 HydrophobicContact CG-CD1 3.96Å; L309-L313 HydrophobicContact CG-CG 4.21Å; L309-L313 WeakPolarHBondContact O-CG 3.29Å; L309-L313 PolarHBondContact O-N 3.38Å; L309-L349 HydrophobicContact CD1-CD2 4.39Å; L309-Y352 HydrophobicContact CB-CD1 3.99Å; L309-Y352 HydrophobicContact CB-CE1 3.84Å; L309-Y352 HydrophobicContact CB-CG 4.45Å; L309-Y352 HydrophobicContact CD1-CD1 4.18Å; L309-Y352 HydrophobicContact CD1-CD2 3.91Å; L309-Y352 HydrophobicContact CD1-CE2 4.39Å; L309-Y352 HydrophobicContact CD1-CG 3.8Å; L309-Y352 HydrophobicContact CD2-CD1 4.11Å; L309-Y352 HydrophobicContact CD2-CG 4.36Å; L309-Y352 HydrophobicContact CG-CD1 4.33Å; L309-Y352 HydrophobicContact CG-CG 4.43Å; L309-L356 HydrophobicContact CD2-CD1 3.8Å
310P90.2Very high90.9Very high51 Ų5136.5 Ų36.533%0.33120%0.2SC..Hα-helixtrans-52.6-48.5179.9-24.630.9000113.6L306 L312 L313 D314L306-P310 WeakPolarHBondContact O-CD 3.4Å; P310-L312 VanDerWaalsContact C-N 3.34Å; P310-L312 PolarHBondContact O-N 3.4Å; P310-L313 CarbonylContact O-C 3.57Å; P310-L313 WeakPolarHBondContact O-CA 3.15Å; P310-L313 WeakPolarHBondContact O-CB 3.26Å; P310-L313 PolarHBondContact O-N 2.66Å; P310-D314 PolarHBondContact O-N 2.97Å
311P87.4Confident91.3Very high11 Ų1136.5 Ų36.57%0.07120%0.2CC..Hα-helixtrans-65.3-34.4176.112.5-18.4000113.7P281 W308 L313 D314 H315P281-P311 VanDerWaalsContact C-CB 3.4Å; P281-P311 VanDerWaalsContact C-CG 3.47Å; P281-P311 HydrophobicContact CB-CB 4.33Å; P281-P311 HydrophobicContact CB-CG 3.38Å; P281-P311 HydrophobicContact CG-CG 3.76Å; P281-P311 WeakPolarHBondContact O-CB 3.02Å; P281-P311 WeakPolarHBondContact O-CG 2.78Å; W308-P311 WeakPolarHBondContact O-CD 3.4Å; W308-P311 WeakPolarHBondContact O-CG 3.48Å; P311-L313 PolarHBondContact O-N 2.83Å; P311-D314 PolarHBondContact O-N 3.15Å; P311-H315 PolarHBondContact O-N 3.15Å; P311-H315 PolarHBondContact O-ND1 3.13Å
312L91.8Very high91.5Very high0 Ų033 Ų330%019%0.185CC..Hα-helixtrans-59.6-36.9170.5176.366.4000111.5W289 W308 L309 P310 Y322 A345 L348 L349 Y352W289-L312 HydrophobicContact CD2-CD1 4.09Å; W289-L312 HydrophobicContact CG-CD1 4.45Å; W289-L312 HydrophobicContact CZ2-CD1 3.99Å; W308-L312 PolarHBondContact O-N 2.83Å; L309-L312 HydrophobicContact CD1-CD2 4.41Å; L309-L312 WeakPolarHBondContact O-CA 3.1Å; L309-L312 WeakPolarHBondContact O-CB 3.49Å; L309-L312 PolarHBondContact O-N 3.24Å; P310-L312 VanDerWaalsContact C-N 3.34Å; P310-L312 PolarHBondContact O-N 3.4Å; L312-Y322 HydrophobicContact CD1-CE1 3.97Å; L312-Y322 WeakPolarHBondContact O-CE1 3.2Å; L312-Y322 PolarHBondContact O-OH 2.85Å; L312-A345 HydrophobicContact CD1-CB 4.07Å; L312-L348 HydrophobicContact CD1-CD2 4.46Å; L312-L348 HydrophobicContact CD2-CB 4.44Å; L312-L348 HydrophobicContact CD2-CD2 3.77Å; L312-L348 HydrophobicContact CD2-CG 3.87Å; L312-L349 HydrophobicContact CD2-CD2 3.95Å; L312-L349 HydrophobicContact CD2-CG 4.32Å; L312-L349 HydrophobicContact CG-CD2 4.36Å; L312-Y352 HydrophobicContact CD2-CD2 4.09Å; L312-Y352 HydrophobicContact CD2-CE2 4.02Å
313L93.7Very high91.4Very high28 Ų2833.6 Ų33.615%0.14719%0.19CC..Hα-helixtrans-71.9-42175.4-61.2174.4000111.5L11 A15 L309 P310 P311 H315 Q316 L349L11-L313 HydrophobicContact CB-CD1 4.39Å; A15-L313 HydrophobicContact CB-CD2 3.6Å; L309-L313 HydrophobicContact CD1-CD1 4.1Å; L309-L313 HydrophobicContact CD1-CD2 4.15Å; L309-L313 HydrophobicContact CD1-CG 3.89Å; L309-L313 HydrophobicContact CG-CD1 3.96Å; L309-L313 HydrophobicContact CG-CG 4.21Å; L309-L313 WeakPolarHBondContact O-CG 3.29Å; L309-L313 PolarHBondContact O-N 3.38Å; P310-L313 CarbonylContact O-C 3.57Å; P310-L313 WeakPolarHBondContact O-CA 3.15Å; P310-L313 WeakPolarHBondContact O-CB 3.26Å; P310-L313 PolarHBondContact O-N 2.66Å; P311-L313 PolarHBondContact O-N 2.83Å; L313-H315 VanDerWaalsContact C-N 3.28Å; L313-H315 PolarHBondContact O-N 3Å; L313-Q316 VanDerWaalsContact O-CB 3.27Å; L313-Q316 WeakPolarHBondContact O-CB 3.16Å; L313-Q316 PolarHBondContact O-N 2.88Å; L313-Q316 VanDerWaalsContact O-N 3.1Å; L313-L349 HydrophobicContact CD2-CD2 3.72Å
314D90.3Very high90.7Very high132 Ų13235 Ų3571%0.70620%0.201SC*.Hα-helixtrans-68-25.5-178.8-64.3-26.2000113P310 P311 Q316P310-D314 PolarHBondContact O-N 2.97Å; P311-D314 PolarHBondContact O-N 3.15Å; D314-Q316 PolarHBondContact O-N 3.25Å
315H89.9Confident89.5Confident60 Ų6037.8 Ų37.828%0.27823%0.226SC..THydrogen-bonded Turntrans-75.5-10.6174.3-7968.9000113.5G282 W289 P311 L313 H317 Y322G282-H315 PolarHBondContact O-CE1 3.38Å; G282-H315 PolarHBondContact O-NE2 3.38Å; G282-H315 VanDerWaalsContact O-NE2 3.12Å; W289-H315 HydrophobicContact CH2-CB 4.41Å; W289-H315 HydrophobicContact CZ2-CB 4.26Å; P311-H315 PolarHBondContact O-N 3.15Å; P311-H315 PolarHBondContact O-ND1 3.13Å; L313-H315 VanDerWaalsContact C-N 3.28Å; L313-H315 PolarHBondContact O-N 3Å; H315-H317 PolarHBondContact O-N 3.12Å; H315-Y322 HydrophobicContact CB-CD1 4.18Å; H315-Y322 HydrophobicContact CB-CE1 4.1Å
316Q93.6Very high87.7Confident39 Ų3941.7 Ų41.718%0.18225%0.247CC..SBendtrans-71.1123.8179-166.9175.939.700109.9A15 V19 L313 D314 G320 Y322A15-Q316 PolarHBondContact O-NE2 3.24Å; V19-Q316 VanDerWaalsContact CG2-NE2 3.31Å; L313-Q316 VanDerWaalsContact O-CB 3.27Å; L313-Q316 WeakPolarHBondContact O-CB 3.16Å; L313-Q316 PolarHBondContact O-N 2.88Å; L313-Q316 VanDerWaalsContact O-N 3.1Å; D314-Q316 PolarHBondContact O-N 3.25Å; Q316-G320 PolarHBondContact NE2-O 2.98Å; Q316-Y322 HydrophobicContact CB-CE1 4.01Å; Q316-Y322 HydrophobicContact CB-CE2 4.21Å; Q316-Y322 HydrophobicContact CG-CE2 3.94Å
317H93.7Very high85.9Confident71 Ų7145.8 Ų45.833%0.32928%0.277SS..  trans-65.2152.2173.6-169.6-97.3000110.3H315 T319 G320 C321H315-H317 PolarHBondContact O-N 3.12Å; H317-T319 PolarHBondContact ND1-N 2.99Å; H317-T319 PolarHBondContact ND1-OG1 3.38Å; H317-T319 PolarHBondContact O-N 3.1Å; H317-G320 WeakPolarHBondContact O-CA 3.06Å; H317-G320 PolarHBondContact O-N 2.76Å; H317-C321 WeakPolarHBondContact CB-O 3.27Å; H317-C321 PolarHBondContact N-O 3.3Å
318P94Very high83.8Confident121 Ų12151 Ų5179%0.78631%0.307SS*.THydrogen-bonded Turntrans-54.3-22.2177.4-31.236.7000115.7G320P318-G320 VanDerWaalsContact C-N 3.27Å
319T94.8Very high81.8Confident70 Ų7053.8 Ų53.843%0.42934%0.337SS..THydrogen-bonded Turntrans-75.8-13.6174.454.10000113.5F22 H317 C321F22-T319 WeakPolarHBondContact CB-O 3.38Å; H317-T319 PolarHBondContact ND1-N 2.99Å; H317-T319 PolarHBondContact ND1-OG1 3.38Å; H317-T319 PolarHBondContact O-N 3.1Å; T319-C321 PolarHBondContact OG1-SG 3.39Å
320G95.3Very high79.8Confident0 Ų057.8 Ų57.80%037%0.365CS..SBendtrans100-8.4-175.300000114.8S18 V19 Q316 H317 P318S18-G320 WeakPolarHBondContact OG-CA 3.29Å; V19-G320 WeakPolarHBondContact CA-O 3.02Å; V19-G320 VanDerWaalsContact CG2-O 3.28Å; V19-G320 WeakPolarHBondContact CG2-O 3.4Å; Q316-G320 PolarHBondContact NE2-O 2.98Å; H317-G320 WeakPolarHBondContact O-CA 3.06Å; H317-G320 PolarHBondContact O-N 2.76Å; P318-G320 VanDerWaalsContact C-N 3.27Å
321C95.2Very high77.8Confident0 Ų062.9 Ų62.90%039%0.39CS..  trans-83.9170-17981.50000113F22 H317 T319 C337F22-C321 HydrophobicContact CD1-CB 3.64Å; F22-C321 HydrophobicContact CD2-CB 3.84Å; F22-C321 HydrophobicContact CE1-CB 3.48Å; F22-C321 VanDerWaalsContact CE1-CB 3.48Å; F22-C321 HydrophobicContact CE2-CB 3.71Å; F22-C321 HydrophobicContact CG-CB 3.82Å; F22-C321 HydrophobicContact CZ-CB 3.54Å; H317-C321 WeakPolarHBondContact CB-O 3.27Å; H317-C321 PolarHBondContact N-O 3.3Å; T319-C321 PolarHBondContact OG1-SG 3.39Å; C321-C337 HydrophobicContact CB-CB 3.53Å; C321-C337 WeakPolarHBondContact CB-SG 2.86Å; C321-C337 VanDerWaalsContact SG-CA 3.56Å; C321-C337 WeakPolarHBondContact SG-CB 3.49Å; C321-C337 CovalentContact SG-SG 2.02Å; C321-C337 PolarHBondContact SG-SG 3Å
322Y92.9Very high76Confident0 Ų074.1 Ų74.10%043%0.431CS..  trans-118.8149.7170.2-72.6-92.9000110.4V19 W289 L312 H315 Q316 D338 T342 A345V19-Y322 HydrophobicContact CG2-CD2 4.38Å; V19-Y322 HydrophobicContact CG2-CE2 3.86Å; W289-Y322 AromaticContact CH2-CD1 3.57Å; W289-Y322 HydrophobicContact CH2-CD1 3.57Å; W289-Y322 HydrophobicContact CH2-CE1 4.25Å; W289-Y322 HydrophobicContact CH2-CG 4.33Å; W289-Y322 HydrophobicContact CZ2-CD1 4.37Å; W289-Y322 AromaticContact CZ3-CD1 3.93Å; W289-Y322 HydrophobicContact CZ3-CD1 3.93Å; W289-Y322 HydrophobicContact CZ3-CG 4.27Å; L312-Y322 HydrophobicContact CD1-CE1 3.97Å; L312-Y322 WeakPolarHBondContact O-CE1 3.2Å; L312-Y322 PolarHBondContact O-OH 2.85Å; H315-Y322 HydrophobicContact CB-CD1 4.18Å; H315-Y322 HydrophobicContact CB-CE1 4.1Å; Q316-Y322 HydrophobicContact CB-CE1 4.01Å; Q316-Y322 HydrophobicContact CB-CE2 4.21Å; Q316-Y322 HydrophobicContact CG-CE2 3.94Å; Y322-D338 PolarHBondContact O-N 3.03Å; Y322-T342 PolarHBondContact N-OG1 3.23Å; Y322-T342 PolarHBondContact O-OG1 2.95Å; Y322-A345 HydrophobicContact CD1-CB 4.02Å; Y322-A345 HydrophobicContact CD2-CB 3.45Å; Y322-A345 VanDerWaalsContact CD2-CB 3.45Å; Y322-A345 HydrophobicContact CE1-CB 4.04Å; Y322-A345 HydrophobicContact CE2-CB 3.48Å; Y322-A345 VanDerWaalsContact CE2-CB 3.48Å; Y322-A345 HydrophobicContact CG-CB 3.71Å
323T87.4Confident74.3Confident34 Ų3481.2 Ų81.221%0.20946%0.462CS..PPolyproline II helixtrans-102.9137174.857.70000110A325 P335 K336T323-A325 PolarHBondContact O-N 3Å; T323-P335 HydrophobicContact CG2-CB 3.63Å; T323-K336 VanDerWaalsContact CG2-O 3.26Å; T323-K336 WeakPolarHBondContact CG2-O 3.39Å
324A76.5Confident72.7Confident29 Ų2985.6 Ų85.624%0.2449%0.49CS..PPolyproline II helixtrans-59.5136.6164.800000108.6I326 D338A324-I326 PolarHBondContact O-N 2.85Å; A324-D338 HydrophobicContact CB-CB 3.99Å
325A65.5Low71.6Confident69 Ų6982.6 Ų82.657%0.5748%0.478SS*.PPolyproline II helixtrans-52.4116.117800000109.5D285 T323 S327D285-A325 HydrophobicContact CB-CB 4Å; T323-A325 PolarHBondContact O-N 3Å; A325-S327 PolarHBondContact O-N 3.09Å
326I53.5Low71.3Confident92 Ų9288.1 Ų88.147%0.47250%0.501SS..PPolyproline II helixtrans-69.9120.1-175-59.4173.5000107.6A324 T328 P335A324-I326 PolarHBondContact O-N 2.85Å; I326-T328 PolarHBondContact O-N 2.64Å; I326-T328 VanDerWaalsContact O-N 3.11Å; I326-P335 HydrophobicContact CD1-CB 4.33Å
327S49.9Very low71.2Confident108 Ų10888 Ų8876%0.75550%0.504SS*.PPolyproline II helixtrans-48.5119.8166.4173.80000108.3A325 G329A325-S327 PolarHBondContact O-N 3.09Å; S327-G329 PolarHBondContact O-N 3.3Å
328T44.6Very low71Confident152 Ų15286.2 Ų86.293%0.93350%0.497SS*.SBendtrans-67.329.9-166.246.10000115.2I326I326-T328 PolarHBondContact O-N 2.64Å; I326-T328 VanDerWaalsContact O-N 3.11Å
329G45.7Very low70.8Confident63 Ų6381.2 Ų81.265%0.64946%0.463SS*.  trans-131.472.7-177.300000112.7S327S327-G329 PolarHBondContact O-N 3.3Å
330S49.5Very low70.4Confident84 Ų8478.3 Ų78.359%0.58745%0.445SS*.SBendtrans170.4126.7143.2-1750000110.3
331N48.9Very low70.1Confident157 Ų15778.3 Ų78.384%0.8445%0.445SS*.THydrogen-bonded Turntrans-59.5133.3-178.5-75.5-37.3000112.2
332R49.8Very low70.1Confident247 Ų24778.3 Ų78.393%0.93245%0.445SS*.THydrogen-bonded Turntrans76.536.7168.6-60.1-174.2-178.1176.21.2119.2T334R332-T334 PolarHBondContact O-N 3.32Å
333F55.3Low70Confident149 Ų14978.4 Ų78.465%0.65445%0.445SS*.  trans-81.9116.5158.8-79.9-80.7000110.3
334T60.5Low70Confident120 Ų12076.8 Ų76.874%0.73644%0.435SS*.  trans-54.5125.6162.846.40000107.7R332 K336R332-T334 PolarHBondContact O-N 3.32Å; T334-K336 PolarHBondContact O-N 3.11Å
335P67.8Low70.8Confident70 Ų7075.4 Ų75.446%0.45542%0.424SS..  trans-57108.2-177.722.2-31.9000109.1T323 I326T323-P335 HydrophobicContact CG2-CB 3.63Å; I326-P335 HydrophobicContact CD1-CB 4.33Å
336K83.8Confident72.3Confident175 Ų17572.1 Ų72.176%0.76140%0.397SS*.  trans-82130.2179.5-168.2178.6178.5-177.20108.1T323 T334 D338T323-K336 VanDerWaalsContact CG2-O 3.26Å; T323-K336 WeakPolarHBondContact CG2-O 3.39Å; T334-K336 PolarHBondContact O-N 3.11Å; K336-D338 PolarHBondContact O-N 3.39Å
337C89.8Confident74.2Confident37 Ų3767.8 Ų67.825%0.2538%0.375CS..  trans-52.9132.7170-650000110F22 C321F22-C337 HydrophobicContact CE1-CB 4.34Å; F22-C337 HydrophobicContact CE2-CB 4.1Å; F22-C337 HydrophobicContact CZ-CB 3.56Å; C321-C337 HydrophobicContact CB-CB 3.53Å; C321-C337 WeakPolarHBondContact CB-SG 2.86Å; C321-C337 VanDerWaalsContact SG-CA 3.56Å; C321-C337 WeakPolarHBondContact SG-CB 3.49Å; C321-C337 CovalentContact SG-SG 2.02Å; C321-C337 PolarHBondContact SG-SG 3Å
338D90Very high76.3Confident34 Ų3462.6 Ų62.618%0.18234%0.339CS..  trans-112.5117.6175.8-179.1-109.6000109.3Y322 A324 K336 F340 A341 T342Y322-D338 PolarHBondContact O-N 3.03Å; A324-D338 HydrophobicContact CB-CB 3.99Å; K336-D338 PolarHBondContact O-N 3.39Å; D338-F340 PolarHBondContact O-N 3.32Å; D338-F340 WeakPolarHBondContact OD1-CB 3.48Å; D338-F340 PolarHBondContact OD1-N 2.83Å; D338-A341 HydrophobicContact CB-CB 4Å; D338-A341 PolarHBondContact O-N 3.37Å; D338-A341 VanDerWaalsContact OD1-CB 3.26Å; D338-A341 WeakPolarHBondContact OD1-CB 3.05Å; D338-A341 PolarHBondContact OD1-N 3.08Å; D338-T342 VanDerWaalsContact O-CB 3.27Å; D338-T342 WeakPolarHBondContact O-CB 3.37Å; D338-T342 PolarHBondContact O-N 3.47Å; D338-T342 PolarHBondContact O-OG1 3.4Å
339M90.2Very high78.8Confident16 Ų1655.4 Ų55.48%0.07929%0.294CS..Hα-helixtrans-64.2-31.4-176.2-77.4-61.9-72.200112.5F22 E29 V30 A343F22-M339 HydrophobicContact CD1-SD 4.44Å; F22-M339 HydrophobicContact CE1-SD 3.59Å; F22-M339 VanDerWaalsContact CE1-SD 3.59Å; F22-M339 HydrophobicContact CZ-SD 4.31Å; E29-M339 HydrophobicContact CB-CG 4.14Å; V30-M339 HydrophobicContact CB-CE 4.36Å; V30-M339 HydrophobicContact CG2-CE 3.67Å; M339-A343 WeakPolarHBondContact O-CB 3.43Å; M339-A343 PolarHBondContact O-N 2.96Å
340F86.8Confident81.1Confident9 Ų952.4 Ų52.44%0.03926%0.264CS..Hα-helixtrans-71.7-51.3178.5177.5-99.3000111.4L196 M200 L204 T286 L290 D338 T342 A343 V344L196-F340 HydrophobicContact CD2-CE2 3.91Å; L196-F340 WeakPolarHBondContact O-CE2 3.48Å; M200-F340 HydrophobicContact CE-CE1 3.55Å; M200-F340 HydrophobicContact CE-CE2 4.06Å; M200-F340 HydrophobicContact CE-CZ 3.19Å; M200-F340 HydrophobicContact CG-CE2 3.92Å; M200-F340 HydrophobicContact CG-CZ 3.99Å; M200-F340 HydrophobicContact SD-CZ 4.42Å; L204-F340 HydrophobicContact CD1-CD1 4.45Å; T286-F340 HydrophobicContact CG2-CD1 3.82Å; T286-F340 HydrophobicContact CG2-CE1 3.61Å; L290-F340 HydrophobicContact CD1-CE1 4.03Å; L290-F340 HydrophobicContact CD1-CZ 3.94Å; L290-F340 HydrophobicContact CD2-CZ 4.09Å; L290-F340 HydrophobicContact CG-CZ 4.43Å; D338-F340 PolarHBondContact O-N 3.32Å; D338-F340 WeakPolarHBondContact OD1-CB 3.48Å; D338-F340 PolarHBondContact OD1-N 2.83Å; F340-T342 VanDerWaalsContact C-N 3.25Å; F340-T342 PolarHBondContact O-N 3.45Å; F340-A343 WeakPolarHBondContact O-CB 3.49Å; F340-A343 PolarHBondContact O-N 3.35Å; F340-A343 VanDerWaalsContact O-N 3.11Å; F340-V344 HydrophobicContact CD1-CG2 4.37Å; F340-V344 HydrophobicContact CE1-CG2 3.8Å; F340-V344 HydrophobicContact CE2-CG2 4.07Å; F340-V344 HydrophobicContact CZ-CG2 3.6Å; F340-V344 WeakPolarHBondContact O-CG2 3.23Å; F340-V344 PolarHBondContact O-N 3.37Å
341A89.5Confident83.2Confident0 Ų049 Ų490%024%0.24CC..Hα-helixtrans-57.4-41.9174.700000111.3T286 W289 D338 A343 V344 A345T286-A341 HydrophobicContact CG2-CB 4.06Å; W289-A341 HydrophobicContact CZ3-CB 4.22Å; D338-A341 HydrophobicContact CB-CB 4Å; D338-A341 PolarHBondContact O-N 3.37Å; D338-A341 VanDerWaalsContact OD1-CB 3.26Å; D338-A341 WeakPolarHBondContact OD1-CB 3.05Å; D338-A341 PolarHBondContact OD1-N 3.08Å; A341-A343 PolarHBondContact O-N 3.38Å; A341-V344 PolarHBondContact O-N 3.04Å; A341-A345 VanDerWaalsContact O-CB 3.27Å; A341-A345 WeakPolarHBondContact O-CB 3.09Å; A341-A345 PolarHBondContact O-N 3.08Å
342T94Very high85.4Confident0 Ų041.6 Ų41.60%020%0.2CC..Hα-helixtrans-61.2-43175.8-57.90000111.7V19 F22 Y322 D338 F340 S346V19-T342 HydrophobicContact CB-CG2 4.49Å; V19-T342 HydrophobicContact CG1-CG2 3.38Å; F22-T342 HydrophobicContact CD1-CG2 4.09Å; F22-T342 HydrophobicContact CE1-CG2 4.39Å; Y322-T342 PolarHBondContact N-OG1 3.23Å; Y322-T342 PolarHBondContact O-OG1 2.95Å; D338-T342 VanDerWaalsContact O-CB 3.27Å; D338-T342 WeakPolarHBondContact O-CB 3.37Å; D338-T342 PolarHBondContact O-N 3.47Å; D338-T342 PolarHBondContact O-OG1 3.4Å; F340-T342 VanDerWaalsContact C-N 3.25Å; F340-T342 PolarHBondContact O-N 3.45Å; T342-S346 WeakPolarHBondContact O-CB 3.46Å; T342-S346 PolarHBondContact O-N 3.48Å; T342-S346 PolarHBondContact O-OG 3.26Å
343A91.3Very high87.5Confident1 Ų129.8 Ų29.81%0.00816%0.156CC..Hα-helixtrans-63.7-47.717600000112.1A37 M339 F340 A341 A345 S346 A347A37-A343 HydrophobicContact CB-CB 3.88Å; M339-A343 WeakPolarHBondContact O-CB 3.43Å; M339-A343 PolarHBondContact O-N 2.96Å; F340-A343 WeakPolarHBondContact O-CB 3.49Å; F340-A343 PolarHBondContact O-N 3.35Å; F340-A343 VanDerWaalsContact O-N 3.11Å; A341-A343 PolarHBondContact O-N 3.38Å; A343-A345 PolarHBondContact O-N 2.77Å; A343-S346 PolarHBondContact O-N 3.39Å; A343-S346 PolarHBondContact O-OG 3.38Å; A343-A347 PolarHBondContact O-N 2.91Å; A343-A347 VanDerWaalsContact O-N 3.07Å
344V87.9Confident89.3Confident0 Ų024.8 Ų24.80%013%0.132CC..Hα-helixtrans-60.6-47.8177.9174.50000111L196 T286 W289 L290 L293 F340 A341 S346 A347 L348L196-V344 HydrophobicContact CD2-CG2 4.18Å; T286-V344 HydrophobicContact CG2-CB 4.44Å; T286-V344 HydrophobicContact CG2-CG2 4.34Å; W289-V344 HydrophobicContact CB-CG1 3.65Å; L290-V344 HydrophobicContact CD2-CB 4.41Å; L290-V344 HydrophobicContact CD2-CG1 3.91Å; L290-V344 HydrophobicContact CD2-CG2 3.53Å; L290-V344 HydrophobicContact CG-CG1 3.94Å; L290-V344 HydrophobicContact CG-CG2 4.02Å; L293-V344 HydrophobicContact CD2-CG1 4.42Å; F340-V344 HydrophobicContact CD1-CG2 4.37Å; F340-V344 HydrophobicContact CE1-CG2 3.8Å; F340-V344 HydrophobicContact CE2-CG2 4.07Å; F340-V344 HydrophobicContact CZ-CG2 3.6Å; F340-V344 WeakPolarHBondContact O-CG2 3.23Å; F340-V344 PolarHBondContact O-N 3.37Å; A341-V344 PolarHBondContact O-N 3.04Å; V344-S346 VanDerWaalsContact C-N 3.34Å; V344-S346 PolarHBondContact O-N 2.91Å; V344-A347 PolarHBondContact O-N 2.85Å; V344-L348 WeakPolarHBondContact O-CB 3.44Å; V344-L348 PolarHBondContact O-N 3.03Å
345A93.7Very high90.7Very high0 Ų019.1 Ų19.10%010%0.097CC..Hα-helixtrans-60.1-43.1177.800000111.4W289 L312 Y322 A341 A343 A347 L348 L349W289-A345 HydrophobicContact CE3-CB 4.2Å; W289-A345 HydrophobicContact CZ3-CB 4.26Å; L312-A345 HydrophobicContact CD1-CB 4.07Å; Y322-A345 HydrophobicContact CD1-CB 4.02Å; Y322-A345 HydrophobicContact CD2-CB 3.45Å; Y322-A345 VanDerWaalsContact CD2-CB 3.45Å; Y322-A345 HydrophobicContact CE1-CB 4.04Å; Y322-A345 HydrophobicContact CE2-CB 3.48Å; Y322-A345 VanDerWaalsContact CE2-CB 3.48Å; Y322-A345 HydrophobicContact CG-CB 3.71Å; A341-A345 VanDerWaalsContact O-CB 3.27Å; A341-A345 WeakPolarHBondContact O-CB 3.09Å; A341-A345 PolarHBondContact O-N 3.08Å; A343-A345 PolarHBondContact O-N 2.77Å; A345-A347 PolarHBondContact O-N 3.24Å; A345-L348 CarbonylContact O-C 3.55Å; A345-L348 PolarHBondContact O-N 3.19Å; A345-L349 VanDerWaalsContact O-CG 3.3Å; A345-L349 WeakPolarHBondContact O-CG 3.45Å; A345-L349 PolarHBondContact O-N 3.3Å
346S95.6Very high91.9Very high0 Ų016.1 Ų16.10%08%0.077CC..Hα-helixtrans-62.3-40.117871.30000113.6I41 T342 A343 V344 L349 V350I41-S346 WeakPolarHBondContact CD1-OG 3.29Å; T342-S346 WeakPolarHBondContact O-CB 3.46Å; T342-S346 PolarHBondContact O-N 3.48Å; T342-S346 PolarHBondContact O-OG 3.26Å; A343-S346 PolarHBondContact O-N 3.39Å; A343-S346 PolarHBondContact O-OG 3.38Å; V344-S346 VanDerWaalsContact C-N 3.34Å; V344-S346 PolarHBondContact O-N 2.91Å; S346-L349 PolarHBondContact O-N 3.42Å; S346-V350 PolarHBondContact O-N 2.75Å
347A94Very high92.1Very high1 Ų18.3 Ų8.31%0.0085%0.045CC..Hα-helixtrans-66.7-40.6175.100000111.1A37 F40 L293 A343 V344 A345 V350 C351A37-A347 HydrophobicContact CB-CB 4.39Å; F40-A347 HydrophobicContact CD1-CB 3.77Å; F40-A347 HydrophobicContact CE1-CB 4.05Å; L293-A347 HydrophobicContact CD1-CB 3.72Å; L293-A347 HydrophobicContact CD2-CB 3.7Å; L293-A347 HydrophobicContact CG-CB 4.37Å; A343-A347 PolarHBondContact O-N 2.91Å; A343-A347 VanDerWaalsContact O-N 3.07Å; V344-A347 PolarHBondContact O-N 2.85Å; A345-A347 PolarHBondContact O-N 3.24Å; A347-V350 PolarHBondContact O-N 2.71Å; A347-C351 PolarHBondContact O-N 3.16Å; A347-C351 PolarHBondContact O-SG 3.47Å
348L93.8Very high91.9Very high0 Ų09.2 Ų9.20%05%0.047CC..Hα-helixtrans-65.5-39.6175.8-17857.8000112.3W289 Q292 L304 L312 V344 A345 V350 C351 Y352W289-L348 HydrophobicContact CB-CD2 3.96Å; W289-L348 HydrophobicContact CG-CD2 4.15Å; Q292-L348 HydrophobicContact CB-CD1 3.67Å; Q292-L348 HydrophobicContact CB-CD2 3.97Å; L304-L348 HydrophobicContact CD2-CD1 3.86Å; L312-L348 HydrophobicContact CD1-CD2 4.46Å; L312-L348 HydrophobicContact CD2-CB 4.44Å; L312-L348 HydrophobicContact CD2-CD2 3.77Å; L312-L348 HydrophobicContact CD2-CG 3.87Å; V344-L348 WeakPolarHBondContact O-CB 3.44Å; V344-L348 PolarHBondContact O-N 3.03Å; A345-L348 CarbonylContact O-C 3.55Å; A345-L348 PolarHBondContact O-N 3.19Å; L348-V350 VanDerWaalsContact C-N 3.27Å; L348-V350 PolarHBondContact O-N 2.97Å; L348-C351 HydrophobicContact CD1-CB 4.48Å; L348-C351 WeakPolarHBondContact O-CA 3.47Å; L348-C351 VanDerWaalsContact O-CB 3.32Å; L348-C351 WeakPolarHBondContact O-CB 3.36Å; L348-C351 PolarHBondContact O-N 3.5Å; L348-Y352 HydrophobicContact CD1-CD2 4.1Å; L348-Y352 HydrophobicContact CD1-CE2 3.78Å; L348-Y352 HydrophobicContact CD2-CE2 4.25Å; L348-Y352 HydrophobicContact CG-CD2 3.99Å; L348-Y352 HydrophobicContact CG-CE2 3.77Å; L348-Y352 WeakPolarHBondContact O-CD2 3.37Å; L348-Y352 PolarHBondContact O-N 3.45Å
349L96.6Very high91.7Very high0 Ų011.3 Ų11.30%07%0.069CC..Hα-helixtrans-57.4-40.2173.9-73.7171.8000111.2T12 A15 L16 V19 L309 L312 L313 A345 S346 Y352 I353T12-L349 HydrophobicContact CG2-CB 4.26Å; T12-L349 HydrophobicContact CG2-CD2 3.72Å; A15-L349 HydrophobicContact CB-CD1 4.09Å; A15-L349 HydrophobicContact CB-CD2 4.35Å; L16-L349 HydrophobicContact CB-CD1 4.44Å; V19-L349 HydrophobicContact CG2-CD1 4.23Å; L309-L349 HydrophobicContact CD1-CD2 4.39Å; L312-L349 HydrophobicContact CD2-CD2 3.95Å; L312-L349 HydrophobicContact CD2-CG 4.32Å; L312-L349 HydrophobicContact CG-CD2 4.36Å; L313-L349 HydrophobicContact CD2-CD2 3.72Å; A345-L349 VanDerWaalsContact O-CG 3.3Å; A345-L349 WeakPolarHBondContact O-CG 3.45Å; A345-L349 PolarHBondContact O-N 3.3Å; S346-L349 PolarHBondContact O-N 3.42Å; L349-Y352 CarbonylContact O-C 3.25Å; L349-Y352 PolarHBondContact O-N 3.27Å; L349-I353 VanDerWaalsContact O-CG1 3.31Å; L349-I353 WeakPolarHBondContact O-CG1 3.26Å; L349-I353 PolarHBondContact O-N 3.02Å
350V95.2Very high91.5Very high1 Ų113.4 Ų13.41%0.0068%0.08CC..Hα-helixtrans-64.9-38174.3165.70000112.7L16 F40 I41 Q44 I48 S346 A347 L348 Y352 I353 R354L16-V350 HydrophobicContact CD1-CG2 4.34Å; L16-V350 HydrophobicContact CD2-CG2 3.56Å; F40-V350 HydrophobicContact CE1-CG1 4.3Å; I41-V350 HydrophobicContact CB-CG2 4.03Å; I41-V350 HydrophobicContact CG1-CB 4.42Å; I41-V350 HydrophobicContact CG1-CG2 3.64Å; I41-V350 HydrophobicContact CG2-CG2 3.75Å; Q44-V350 HydrophobicContact CB-CG1 3.51Å; Q44-V350 HydrophobicContact CG-CG1 4.02Å; I48-V350 HydrophobicContact CD1-CG1 4.08Å; S346-V350 PolarHBondContact O-N 2.75Å; A347-V350 PolarHBondContact O-N 2.71Å; L348-V350 VanDerWaalsContact C-N 3.27Å; L348-V350 PolarHBondContact O-N 2.97Å; V350-Y352 VanDerWaalsContact C-N 3.3Å; V350-Y352 PolarHBondContact O-N 3.47Å; V350-I353 PolarHBondContact O-N 2.76Å; V350-R354 PolarHBondContact O-N 3.32Å
351C93.4Very high91.5Very high13 Ų1313.5 Ų13.59%0.0888%0.082CC..Hα-helixtrans-60.3-42.4172.4-630000111.1L304 A347 L348 R354 C355L304-C351 HydrophobicContact CD1-CB 4.05Å; L304-C351 HydrophobicContact CD2-CB 3.81Å; A347-C351 PolarHBondContact O-N 3.16Å; A347-C351 PolarHBondContact O-SG 3.47Å; L348-C351 HydrophobicContact CD1-CB 4.48Å; L348-C351 WeakPolarHBondContact O-CA 3.47Å; L348-C351 VanDerWaalsContact O-CB 3.32Å; L348-C351 WeakPolarHBondContact O-CB 3.36Å; L348-C351 PolarHBondContact O-N 3.5Å; C351-R354 PolarHBondContact O-N 3.33Å; C351-C355 WeakPolarHBondContact O-CB 3.47Å; C351-C355 PolarHBondContact O-N 2.96Å
352Y94.7Very high91.3Very high0 Ų014.3 Ų14.30%09%0.086CC..Hα-helixtrans-66.4-40.4173.8-80.8-72.9000113.1Q292 L304 R305 L309 L312 L348 L349 V350 R354 C355 L356Q292-Y352 PolarHBondContact OE1-OH 3Å; L304-Y352 HydrophobicContact CB-CD1 4.36Å; L304-Y352 HydrophobicContact CB-CE1 4Å; L304-Y352 HydrophobicContact CD2-CD1 4.29Å; L304-Y352 HydrophobicContact CD2-CD2 4.12Å; L304-Y352 HydrophobicContact CD2-CE1 4.14Å; L304-Y352 HydrophobicContact CD2-CE2 3.95Å; L304-Y352 HydrophobicContact CD2-CG 4.28Å; R305-Y352 PolarHBondContact O-OH 3.41Å; L309-Y352 HydrophobicContact CB-CD1 3.99Å; L309-Y352 HydrophobicContact CB-CE1 3.84Å; L309-Y352 HydrophobicContact CB-CG 4.45Å; L309-Y352 HydrophobicContact CD1-CD1 4.18Å; L309-Y352 HydrophobicContact CD1-CD2 3.91Å; L309-Y352 HydrophobicContact CD1-CE2 4.39Å; L309-Y352 HydrophobicContact CD1-CG 3.8Å; L309-Y352 HydrophobicContact CD2-CD1 4.11Å; L309-Y352 HydrophobicContact CD2-CG 4.36Å; L309-Y352 HydrophobicContact CG-CD1 4.33Å; L309-Y352 HydrophobicContact CG-CG 4.43Å; L312-Y352 HydrophobicContact CD2-CD2 4.09Å; L312-Y352 HydrophobicContact CD2-CE2 4.02Å; L348-Y352 HydrophobicContact CD1-CD2 4.1Å; L348-Y352 HydrophobicContact CD1-CE2 3.78Å; L348-Y352 HydrophobicContact CD2-CE2 4.25Å; L348-Y352 HydrophobicContact CG-CD2 3.99Å; L348-Y352 HydrophobicContact CG-CE2 3.77Å; L348-Y352 WeakPolarHBondContact O-CD2 3.37Å; L348-Y352 PolarHBondContact O-N 3.45Å; L349-Y352 CarbonylContact O-C 3.25Å; L349-Y352 PolarHBondContact O-N 3.27Å; V350-Y352 VanDerWaalsContact C-N 3.3Å; V350-Y352 PolarHBondContact O-N 3.47Å; Y352-R354 VanDerWaalsContact C-N 3.33Å; Y352-R354 PolarHBondContact O-N 3.01Å; Y352-C355 WeakPolarHBondContact O-CB 3.25Å; Y352-C355 PolarHBondContact O-N 3.04Å; Y352-L356 WeakPolarHBondContact O-CB 3.34Å; Y352-L356 VanDerWaalsContact O-CG 3.31Å; Y352-L356 WeakPolarHBondContact O-CG 3.19Å; Y352-L356 PolarHBondContact O-N 3.23Å
353I94.5Very high90.7Very high0 Ų018.6 Ų18.60%011%0.113CC..Hα-helixtrans-57.3-48.4174.8-72167.1000110.1L9 T12 I13 L16 I48 L66 L349 V350 C355 L356 A357L9-I353 HydrophobicContact CD1-CB 4.3Å; L9-I353 HydrophobicContact CD1-CG1 4.39Å; L9-I353 HydrophobicContact CD1-CG2 3.93Å; T12-I353 HydrophobicContact CG2-CD1 4.31Å; T12-I353 HydrophobicContact CG2-CG1 3.62Å; I13-I353 HydrophobicContact CG1-CD1 3.88Å; I13-I353 HydrophobicContact CG1-CG1 4.03Å; I13-I353 HydrophobicContact CG1-CG2 4.4Å; L16-I353 HydrophobicContact CB-CD1 4.29Å; L16-I353 HydrophobicContact CD2-CD1 3.63Å; I48-I353 HydrophobicContact CD1-CG2 4.27Å; I48-I353 HydrophobicContact CG2-CG2 4.28Å; L66-I353 HydrophobicContact CD2-CG2 3.83Å; L349-I353 VanDerWaalsContact O-CG1 3.31Å; L349-I353 WeakPolarHBondContact O-CG1 3.26Å; L349-I353 PolarHBondContact O-N 3.02Å; V350-I353 PolarHBondContact O-N 2.76Å; I353-C355 VanDerWaalsContact C-N 3.32Å; I353-C355 PolarHBondContact O-N 3.4Å; I353-L356 PolarHBondContact O-N 2.6Å; I353-A357 WeakPolarHBondContact O-CB 3.29Å; I353-A357 PolarHBondContact O-N 3.23Å
354R91.6Very high89.9Confident44 Ų4421.9 Ų21.917%0.16613%0.133CC..Hα-helixtrans-58.6-48176-177169.8179.5100.56.6111.3I48 E51 Y106 V350 C351 Y352 A357 M358I48-R354 HydrophobicContact CD1-CB 3.66Å; I48-R354 HydrophobicContact CD1-CG 4.37Å; I48-R354 HydrophobicContact CG1-CB 3.71Å; I48-R354 HydrophobicContact CG1-CG 3.88Å; E51-R354 IonicContact OE1-CZ 3.97Å; E51-R354 IonicContact OE1-NH1 3.07Å; E51-R354 PolarHBondContact OE1-NH1 3.4Å; E51-R354 IonicContact OE1-NH2 2.92Å; E51-R354 PolarHBondContact OE1-NH2 3.2Å; E51-R354 IonicContact OE2-CZ 3.1Å; E51-R354 IonicContact OE2-NE 2.84Å; E51-R354 IonicContact OE2-NH1 3.85Å; E51-R354 PolarHBondContact OE2-NH1 2.64Å; E51-R354 IonicContact OE2-NH2 3.3Å; E51-R354 PolarHBondContact OE2-NH2 3.37Å; Y106-R354 VanDerWaalsContact CD1-NH1 3.3Å; V350-R354 PolarHBondContact O-N 3.32Å; C351-R354 PolarHBondContact O-N 3.33Å; Y352-R354 VanDerWaalsContact C-N 3.33Å; Y352-R354 PolarHBondContact O-N 3.01Å; R354-A357 PolarHBondContact O-N 2.86Å; R354-M358 WeakPolarHBondContact O-CB 3.17Å; R354-M358 WeakPolarHBondContact O-CG 3.39Å; R354-M358 PolarHBondContact O-N 3.38Å
355C90.8Very high88.7Confident0 Ų028.8 Ų28.80%017%0.17CC..Hα-helixtrans-59.5-47.4-178.1-179.60000112.6L304 C351 Y352 I353 M358 A359 D360 C361L304-C355 HydrophobicContact CB-CB 4.5Å; L304-C355 HydrophobicContact CD1-CB 3.76Å; C351-C355 WeakPolarHBondContact O-CB 3.47Å; C351-C355 PolarHBondContact O-N 2.96Å; Y352-C355 WeakPolarHBondContact O-CB 3.25Å; Y352-C355 PolarHBondContact O-N 3.04Å; I353-C355 VanDerWaalsContact C-N 3.32Å; I353-C355 PolarHBondContact O-N 3.4Å; C355-M358 PolarHBondContact O-N 3.29Å; C355-A359 PolarHBondContact O-N 3.39Å; C355-D360 PolarHBondContact O-N 3.26Å; C355-C361 HydrophobicContact CB-CB 4.46Å; C355-C361 WeakPolarHBondContact CB-SG 3.39Å; C355-C361 WeakPolarHBondContact SG-CA 3.42Å; C355-C361 WeakPolarHBondContact SG-CB 3.22Å; C355-C361 PolarHBondContact SG-N 2.89Å; C355-C361 VanDerWaalsContact SG-N 3.44Å; C355-C361 CovalentContact SG-SG 2.03Å; C355-C361 PolarHBondContact SG-SG 3.03Å
356L91.9Very high86.9Confident7 Ų730.7 Ų30.74%0.03719%0.189CC..Hα-helixtrans-68.9-45.5177.7-73.7166.9000111.8L8 L9 L306 L309 Y352 I353 M358 A359 C361L8-L356 HydrophobicContact CB-CD1 4.09Å; L8-L356 HydrophobicContact CB-CD2 4.09Å; L8-L356 HydrophobicContact CD1-CD2 4.26Å; L9-L356 HydrophobicContact CB-CB 4.23Å; L9-L356 HydrophobicContact CB-CD1 4.4Å; L9-L356 HydrophobicContact CD1-CB 4.07Å; L306-L356 HydrophobicContact CD2-CD2 3.62Å; L306-L356 HydrophobicContact CD2-CG 4.47Å; L309-L356 HydrophobicContact CD2-CD1 3.8Å; Y352-L356 WeakPolarHBondContact O-CB 3.34Å; Y352-L356 VanDerWaalsContact O-CG 3.31Å; Y352-L356 WeakPolarHBondContact O-CG 3.19Å; Y352-L356 PolarHBondContact O-N 3.23Å; I353-L356 PolarHBondContact O-N 2.6Å; L356-M358 PolarHBondContact O-N 3.39Å; L356-A359 PolarHBondContact O-N 2.87Å; L356-C361 PolarHBondContact N-SG 3.33Å; L356-C361 VanDerWaalsContact N-SG 3.4Å
357A89.5Confident84.9Confident11 Ų1136.2 Ų36.29%0.09121%0.213CC..Hα-helixtrans-58.8-32.5177.800000111.6L9 I48 L55 L62 I353 R354L9-A357 HydrophobicContact CD2-CB 4.38Å; I48-A357 HydrophobicContact CG2-CB 3.78Å; L55-A357 WeakPolarHBondContact CD1-O 3.39Å; L62-A357 HydrophobicContact CD2-CB 4.16Å; I353-A357 WeakPolarHBondContact O-CB 3.29Å; I353-A357 PolarHBondContact O-N 3.23Å; R354-A357 PolarHBondContact O-N 2.86Å
358M85.8Confident82.9Confident57 Ų5737.3 Ų37.328%0.28123%0.225SC..THydrogen-bonded Turntrans-93.23.1179.1-60.4-57.8-70.900114.3E51 L55 R354 C355 L356 D360E51-M358 HydrophobicContact CB-CE 3.9Å; E51-M358 HydrophobicContact CB-SD 3.56Å; E51-M358 VanDerWaalsContact CB-SD 3.56Å; L55-M358 HydrophobicContact CD1-CE 4.48Å; L55-M358 HydrophobicContact CD1-SD 3.8Å; R354-M358 WeakPolarHBondContact O-CB 3.17Å; R354-M358 WeakPolarHBondContact O-CG 3.39Å; R354-M358 PolarHBondContact O-N 3.38Å; C355-M358 PolarHBondContact O-N 3.29Å; L356-M358 PolarHBondContact O-N 3.39Å; M358-D360 HydrophobicContact CB-CB 4.22Å; M358-D360 PolarHBondContact O-N 2.84Å; M358-D360 VanDerWaalsContact O-N 3.16Å
359A85.5Confident80.6Confident78 Ų7845.1 Ų45.165%0.64526%0.262SS*.THydrogen-bonded Turntrans48.738.1-174.700000113.3C355 L356C355-A359 PolarHBondContact O-N 3.39Å; L356-A359 PolarHBondContact O-N 2.87Å
360D85.8Confident78.1Confident59 Ų5950 Ų5032%0.31629%0.293SS..  trans-128.832.1-169.8-175.917.5000109.8R109 C355 M358R109-D360 WeakPolarHBondContact CD-OD2 3.3Å; R109-D360 IonicContact CZ-OD1 3.37Å; R109-D360 IonicContact CZ-OD2 3.08Å; R109-D360 IonicContact NE-OD1 3.45Å; R109-D360 IonicContact NE-OD2 2.98Å; R109-D360 PolarHBondContact NE-OD2 2.79Å; R109-D360 PolarHBondContact NH1-O 3.37Å; R109-D360 IonicContact NH1-OD1 3.3Å; R109-D360 IonicContact NH1-OD2 3.85Å; R109-D360 VanDerWaalsContact NH2-CB 3.27Å; R109-D360 VanDerWaalsContact NH2-CG 3.35Å; R109-D360 PolarHBondContact NH2-O 2.66Å; R109-D360 IonicContact NH2-OD2 3.82Å; R109-D360 PolarHBondContact NH2-OD2 3.47Å; R109-D360 VanDerWaalsContact NH2-OD2 3.13Å; C355-D360 PolarHBondContact O-N 3.26Å; M358-D360 HydrophobicContact CB-CB 4.22Å; M358-D360 PolarHBondContact O-N 2.84Å; M358-D360 VanDerWaalsContact O-N 3.16Å
361C86.6Confident75.6Confident12 Ų1251.8 Ų51.88%0.08131%0.308CS..SBendtrans-79.5150.9168.8-64.10000111.6L306 C355 L356 T363L306-C361 HydrophobicContact CD1-CB 4.18Å; L306-C361 HydrophobicContact CD2-CB 3.39Å; L306-C361 HydrophobicContact CG-CB 3.54Å; C355-C361 HydrophobicContact CB-CB 4.46Å; C355-C361 WeakPolarHBondContact CB-SG 3.39Å; C355-C361 WeakPolarHBondContact SG-CA 3.42Å; C355-C361 WeakPolarHBondContact SG-CB 3.22Å; C355-C361 PolarHBondContact SG-N 2.89Å; C355-C361 VanDerWaalsContact SG-N 3.44Å; C355-C361 CovalentContact SG-SG 2.03Å; C355-C361 PolarHBondContact SG-SG 3.03Å; L356-C361 PolarHBondContact N-SG 3.33Å; L356-C361 VanDerWaalsContact N-SG 3.4Å; C361-T363 PolarHBondContact O-N 2.84Å
362D84.7Confident73Confident16 Ų1654.8 Ų54.89%0.08633%0.326CS..BIsolated β-bridgetrans-70.7108.1172.2-1758.7000108.1E302 L304 R305 L306 T364E302-D362 WeakPolarHBondContact CA-OD2 3.35Å; L304-D362 PolarHBondContact O-N 3.23Å; R305-D362 WeakPolarHBondContact CA-O 3.35Å; R305-D362 HydrophobicContact CG-CB 3.81Å; R305-D362 VanDerWaalsContact CG-OD2 3.31Å; R305-D362 WeakPolarHBondContact CG-OD2 3.26Å; R305-D362 IonicContact NE-OD2 2.9Å; R305-D362 PolarHBondContact NE-OD2 3.41Å; L306-D362 PolarHBondContact N-O 2.93Å; D362-T364 VanDerWaalsContact C-N 3.26Å; D362-T364 VanDerWaalsContact OD1-CB 3.31Å; D362-T364 WeakPolarHBondContact OD1-CB 3.48Å; D362-T364 VanDerWaalsContact OD1-CG2 3.28Å; D362-T364 WeakPolarHBondContact OD1-CG2 3.4Å; D362-T364 PolarHBondContact OD1-N 2.58Å; D362-T364 PolarHBondContact OD1-OG1 2.64Å; D362-T364 PolarHBondContact OD2-OG1 3.49Å
363T81.3Confident70.3Confident91 Ų9157 Ų5756%0.55834%0.344SS*.  trans-88.87.7177.967.10000111.8L306 C361 D365L306-T363 HydrophobicContact CD1-CG2 3.9Å; C361-T363 PolarHBondContact O-N 2.84Å; T363-D365 PolarHBondContact O-N 3.29Å
364T75.1Confident67.7Low69 Ų6963.9 Ų63.942%0.42337%0.371SS..  trans-64.5104.8176.954.20000109.8D362 G366D362-T364 VanDerWaalsContact C-N 3.26Å; D362-T364 VanDerWaalsContact OD1-CB 3.31Å; D362-T364 WeakPolarHBondContact OD1-CB 3.48Å; D362-T364 VanDerWaalsContact OD1-CG2 3.28Å; D362-T364 WeakPolarHBondContact OD1-CG2 3.4Å; D362-T364 PolarHBondContact OD1-N 2.58Å; D362-T364 PolarHBondContact OD1-OG1 2.64Å; D362-T364 PolarHBondContact OD2-OG1 3.49Å; T364-G366 PolarHBondContact O-N 2.92Å
365D63.1Low65.1Low146 Ų14665.8 Ų65.878%0.78138%0.384SS*.  trans-76.8100.2164.7-72.5-26.3000107.1T363T363-D365 PolarHBondContact O-N 3.29Å
366G54.8Low62.8Low40 Ų4072.9 Ų72.941%0.41241%0.412SS..SBendtrans152.2147.9178.700000112.4R305 T364R305-G366 PolarHBondContact NH1-O 2.71Å; R305-G366 PolarHBondContact NH2-O 3.34Å; T364-G366 PolarHBondContact O-N 2.92Å
367F53.3Low60.9Low115 Ų11580.1 Ų80.150%0.50445%0.451SS..  trans-74.1131.8167.2-53.5-65.7000107.1E272 V276E272-F367 HydrophobicContact CG-CB 4.44Å; E272-F367 HydrophobicContact CG-CD1 4.07Å; E272-F367 WeakPolarHBondContact OE1-CA 3.5Å; V276-F367 HydrophobicContact CB-CD1 4.4Å; V276-F367 HydrophobicContact CB-CE1 4.14Å; V276-F367 HydrophobicContact CB-CZ 4.29Å; V276-F367 HydrophobicContact CG1-CE2 4.33Å; V276-F367 HydrophobicContact CG1-CZ 4.35Å; V276-F367 HydrophobicContact CG2-CB 4.27Å; V276-F367 HydrophobicContact CG2-CD1 3.06Å; V276-F367 HydrophobicContact CG2-CD2 3.99Å; V276-F367 HydrophobicContact CG2-CE1 3.13Å; V276-F367 HydrophobicContact CG2-CE2 4.06Å; V276-F367 HydrophobicContact CG2-CG 3.5Å; V276-F367 VanDerWaalsContact CG2-CG 3.5Å; V276-F367 HydrophobicContact CG2-CZ 3.65Å
368G52.2Low58.8Low24 Ų2481.4 Ų81.425%0.24746%0.461CS..  trans-50.5149.8168.700000108.7E272 P370E272-G368 PolarHBondContact OE1-N 2.71Å; G368-P370 VanDerWaalsContact O-N 3.15Å
369E45.9Very low56.6Low165 Ų16583 Ų8377%0.77149%0.493SS*.SBendtrans-39.7126.2-174.9-73.6-169.515800110.9A371E369-A371 PolarHBondContact O-N 3.07Å
370P45.1Very low54.4Low103 Ų10381.6 Ų81.667%0.66949%0.485SS*.  trans-53.7142.7-178.522.2-31.9000108.3G368 V372G368-P370 VanDerWaalsContact O-N 3.15Å; P370-V372 PolarHBondContact O-N 3.47Å
371A42.3Very low52.3Low38 Ų3883.4 Ų83.431%0.31451%0.509SS..  trans-48.398.3-17600000113E369 A373E369-A371 PolarHBondContact O-N 3.07Å; A371-A373 PolarHBondContact O-N 3.04Å
372V39.4Very low50.1Low75 Ų7586.4 Ų86.446%0.45553%0.53SS..  trans-71106.7171.7-174.30000107.1P370 Y374P370-V372 PolarHBondContact O-N 3.47Å; V372-Y374 HydrophobicContact CB-CE2 4.45Å; V372-Y374 HydrophobicContact CG1-CE2 4.4Å; V372-Y374 PolarHBondContact O-N 3.49Å
373A37.8Very low48Very low46 Ų4694.4 Ų94.438%0.3857%0.567SS.*  trans-71.3117.7166.900000107.6A371 D375 N392A371-A373 PolarHBondContact O-N 3.04Å; A373-D375 PolarHBondContact O-N 3.12Å; A373-N392 WeakPolarHBondContact CB-OD1 3.46Å
374Y38.5Very low46Very low146 Ų14695.3 Ų95.357%0.57357%0.568SS**  trans-82.3110.6169.2-69.6-88.3000107.6V372 Y376V372-Y374 HydrophobicContact CB-CE2 4.45Å; V372-Y374 HydrophobicContact CG1-CE2 4.4Å; V372-Y374 PolarHBondContact O-N 3.49Å; Y374-Y376 HydrophobicContact CG-CE2 4.48Å; Y374-Y376 PolarHBondContact O-N 3.35Å
375D38.7Very low44.4Very low84 Ų8496.8 Ų96.845%0.44957%0.573SS.*  trans-76101.2164.3-174.2-3.9000108A373 N377 L384A373-D375 PolarHBondContact O-N 3.12Å; D375-N377 VanDerWaalsContact C-N 3.28Å; D375-N377 WeakPolarHBondContact OD1-CB 3.41Å; D375-N377 PolarHBondContact OD1-N 3.03Å; D375-L384 HydrophobicContact CB-CD1 4.48Å
376Y42.3Very low43.6Very low148 Ų14894.4 Ų94.458%0.5857%0.568SS**SBendtrans-77.7-12.8179.7-79.7-80.4000113.2R119 Y374 A378R119-Y376 PolarHBondContact NH1-OH 2.06Å; Y374-Y376 HydrophobicContact CG-CE2 4.48Å; Y374-Y376 PolarHBondContact O-N 3.35Å; Y376-A378 VanDerWaalsContact C-N 3.34Å
377N50.2Low42.9Very low160 Ų16098.8 Ų98.886%0.85658%0.582SS**SBendtrans-76.1-28.4176.3-69.9-21.6000111.2D375 G379D375-N377 VanDerWaalsContact C-N 3.28Å; D375-N377 WeakPolarHBondContact OD1-CB 3.41Å; D375-N377 PolarHBondContact OD1-N 3.03Å; N377-G379 PolarHBondContact O-N 2.78Å
378A46.4Very low42Very low37 Ų3797.5 Ų97.531%0.30658%0.58SS.*SBendtrans-79.5101.116400000107.9Y376 G380Y376-A378 VanDerWaalsContact C-N 3.34Å; A378-G380 PolarHBondContact O-N 3.39Å
379G40.5Very low41.1Very low92 Ų92104.5 Ų104.595%0.94861%0.608SS**SBendtrans-65.452-176.700000115.9N377N377-G379 PolarHBondContact O-N 2.78Å
380G39.4Very low40.5Very low47 Ų47104.2 Ų104.249%0.48560%0.6SS.*SBendtrans-177.8149.4179.600000109.7A378 S382A378-G380 PolarHBondContact O-N 3.39Å; G380-S382 PolarHBondContact O-N 2.94Å
381A41.8Very low40.1Very low98 Ų98105 Ų10581%0.8160%0.598SS**  trans-7054.2178.300000112.1Q383A381-Q383 VanDerWaalsContact C-N 3.32Å; A381-Q383 PolarHBondContact O-N 3.49Å
382S40.3Very low40.1Very low75 Ų75104.2 Ų104.252%0.52459%0.589SS.*  trans-68.695.5169.351.10000107.9G380 L384G380-S382 PolarHBondContact O-N 2.94Å; S382-L384 PolarHBondContact O-N 2.81Å
383Q39.9Very low39.8Very low184 Ų184107.8 Ų107.886%0.8659%0.594SS**  trans-53.1106.6163-163.4175.51800106.6A381 D385A381-Q383 VanDerWaalsContact C-N 3.32Å; A381-Q383 PolarHBondContact O-N 3.49Å; Q383-D385 PolarHBondContact O-N 3.16Å
384L39.8Very low39.8Very low109 Ų109108.3 Ų108.357%0.57159%0.593SS**  trans-60.3133.9-178.2-90.6117000109.7D375 S382D375-L384 HydrophobicContact CB-CD1 4.48Å; S382-L384 PolarHBondContact O-N 2.81Å
385D41.8Very low39.7Very low100 Ų100103.9 Ų103.954%0.53558%0.581SS.*  trans-48.4135.4-174.3-172.22.3000112.3Q383 N387 N388Q383-D385 PolarHBondContact O-N 3.16Å; D385-N387 PolarHBondContact O-N 3.33Å; D385-N388 WeakPolarHBondContact O-CB 3.34Å; D385-N388 PolarHBondContact O-N 3.37Å
386S45Very low39.6Very low96 Ų96104.3 Ų104.367%0.67158%0.582SS**THydrogen-bonded Turntrans-48.4-23.9-177.557.30000115.8N388S386-N388 VanDerWaalsContact C-N 3.32Å
387N39.8Very low39.3Very low133 Ų133100 Ų10071%0.71157%0.568SS**THydrogen-bonded Turntrans-78.6-17.3177.7-67.6-37.4000113.4D385 M389D385-N387 PolarHBondContact O-N 3.33Å; N387-M389 PolarHBondContact O-N 3.47Å; N387-M389 VanDerWaalsContact O-N 3.16Å
388N36.1Very low38.6Very low88 Ų8895 Ų9547%0.47154%0.539SS..  trans-87.867.9169.6-85.9-25.3000108.6D385 S386 W390D385-N388 WeakPolarHBondContact O-CB 3.34Å; D385-N388 PolarHBondContact O-N 3.37Å; S386-N388 VanDerWaalsContact C-N 3.32Å; N388-W390 PolarHBondContact O-N 2.77Å; N388-W390 PolarHBondContact OD1-NE1 2.94Å
389M33.2Very low38.2Very low170 Ų17097.4 Ų97.484%0.83755%0.547SS*.  trans-62.659.3158.9-87.1-169.8-65.800110.1N387 L391N387-M389 PolarHBondContact O-N 3.47Å; N387-M389 VanDerWaalsContact O-N 3.16Å; M389-L391 PolarHBondContact O-N 3.34Å
390W31.9Very low38.1Very low160 Ų16096.5 Ų96.561%0.60652%0.518SS*.  trans-8774.9160.1-6481.1000105N388 N392 R393N388-W390 PolarHBondContact O-N 2.77Å; N388-W390 PolarHBondContact OD1-NE1 2.94Å; W390-N392 PolarHBondContact O-N 2.89Å; W390-R393 HydrophobicContact CE3-CB 4.07Å; W390-R393 HydrophobicContact CZ3-CB 4.43Å
391L36.7Very low37.8Very low118 Ų11896.2 Ų96.262%0.61851%0.511SS*.  trans-63.288.3162.1-122.4150.7000105.6M389 R393M389-L391 PolarHBondContact O-N 3.34Å; L391-R393 VanDerWaalsContact C-N 3.32Å; L391-R393 PolarHBondContact O-N 3.28Å
392N42Very low37.5Very low22 Ų2295 Ų9512%0.11849%0.49CS..  trans16.772.9178.2-90.4-41.5000112.5A373 W390 T394 V395 L396A373-N392 WeakPolarHBondContact CB-OD1 3.46Å; W390-N392 PolarHBondContact O-N 2.89Å; N392-T394 PolarHBondContact O-N 3.29Å; N392-T394 PolarHBondContact OD1-OG1 3.4Å; N392-V395 HydrophobicContact CB-CB 3.66Å; N392-V395 HydrophobicContact CB-CG2 3.63Å; N392-V395 PolarHBondContact O-N 3Å; N392-L396 PolarHBondContact O-N 3.35Å
393R33.7Very low37.1Very low150 Ų15093.5 Ų93.557%0.56648%0.479SS*.Hα-helixtrans-48.4-28.5159.5-150.3-174.7-176.1166.64.1108.5W390 L391 L396 E397W390-R393 HydrophobicContact CE3-CB 4.07Å; W390-R393 HydrophobicContact CZ3-CB 4.43Å; L391-R393 VanDerWaalsContact C-N 3.32Å; L391-R393 PolarHBondContact O-N 3.28Å; R393-L396 CarbonylContact O-C 3.13Å; R393-E397 WeakPolarHBondContact CD-OE1 3.1Å; R393-E397 HydrophobicContact CG-CG 4.11Å; R393-E397 VanDerWaalsContact CG-OE1 3.3Å; R393-E397 WeakPolarHBondContact CG-OE1 3.49Å; R393-E397 IonicContact NE-OE1 2.68Å; R393-E397 PolarHBondContact NE-OE1 3.2Å; R393-E397 WeakPolarHBondContact O-CA 3.39Å; R393-E397 WeakPolarHBondContact O-CB 3.47Å; R393-E397 VanDerWaalsContact O-CD 3.27Å; R393-E397 WeakPolarHBondContact O-CG 3.35Å; R393-E397 PolarHBondContact O-N 3.42Å
394T38.6Very low36.6Very low58 Ų5891.5 Ų91.536%0.35646%0.464SS..Hα-helixtrans-74.4-26.3170.950.70000118N392 E397 Q398N392-T394 PolarHBondContact O-N 3.29Å; N392-T394 PolarHBondContact OD1-OG1 3.4Å; T394-E397 CarbonylContact O-C 3.46Å; T394-Q398 VanDerWaalsContact O-CA 3.31Å; T394-Q398 WeakPolarHBondContact O-CA 3.29Å; T394-Q398 WeakPolarHBondContact O-CB 3.34Å; T394-Q398 WeakPolarHBondContact O-CG 3.37Å; T394-Q398 PolarHBondContact O-N 3.18Å
395V35.3Very low36Very low53 Ų5390 Ų9032%0.32146%0.455SS..Hα-helixtrans-85.5-38173172.70000109.1N392 Q398 L399N392-V395 HydrophobicContact CB-CB 3.66Å; N392-V395 HydrophobicContact CB-CG2 3.63Å; N392-V395 PolarHBondContact O-N 3Å; V395-Q398 PolarHBondContact O-N 2.95Å; V395-L399 HydrophobicContact CG1-CD1 4.36Å; V395-L399 WeakPolarHBondContact O-CB 3.35Å; V395-L399 WeakPolarHBondContact O-CG 3.47Å; V395-L399 PolarHBondContact O-N 3.36Å
396L36.2Very low35.2Very low92 Ų9294 Ų9448%0.48247%0.47SS..Hα-helixtrans-68.4-36.1166.7-101.3157.7000111.3N392 R393 Q398 L399 E400N392-L396 PolarHBondContact O-N 3.35Å; R393-L396 CarbonylContact O-C 3.13Å; L396-Q398 VanDerWaalsContact C-N 3.33Å; L396-L399 CarbonylContact O-C 3.09Å; L396-E400 WeakPolarHBondContact O-CA 3.45Å; L396-E400 WeakPolarHBondContact O-CB 3.47Å; L396-E400 PolarHBondContact O-N 2.95Å
397E36.9Very low34.3Very low59 Ų5992.1 Ų92.128%0.27646%0.455SS..Hα-helixtrans-80.7-6.8169.8-73.5162.1172.700111.3R393 T394 E400 A401R393-E397 WeakPolarHBondContact CD-OE1 3.1Å; R393-E397 HydrophobicContact CG-CG 4.11Å; R393-E397 VanDerWaalsContact CG-OE1 3.3Å; R393-E397 WeakPolarHBondContact CG-OE1 3.49Å; R393-E397 IonicContact NE-OE1 2.68Å; R393-E397 PolarHBondContact NE-OE1 3.2Å; R393-E397 WeakPolarHBondContact O-CA 3.39Å; R393-E397 WeakPolarHBondContact O-CB 3.47Å; R393-E397 VanDerWaalsContact O-CD 3.27Å; R393-E397 WeakPolarHBondContact O-CG 3.35Å; R393-E397 PolarHBondContact O-N 3.42Å; T394-E397 CarbonylContact O-C 3.46Å; E397-E400 CarbonylContact O-C 3.5Å; E397-A401 WeakPolarHBondContact O-CA 3.42Å; E397-A401 WeakPolarHBondContact O-CB 3.14Å; E397-A401 PolarHBondContact O-N 3.32Å
398Q36Very low33.7Very low53 Ų5397.4 Ų97.425%0.24847%0.465CS..Hα-helixtrans-96.6-36.2167.8-86.9176.9500109.5M120 T394 V395 L396 A401 I402M120-Q398 PolarHBondContact SD-NE2 3.45Å; T394-Q398 VanDerWaalsContact O-CA 3.31Å; T394-Q398 WeakPolarHBondContact O-CA 3.29Å; T394-Q398 WeakPolarHBondContact O-CB 3.34Å; T394-Q398 WeakPolarHBondContact O-CG 3.37Å; T394-Q398 PolarHBondContact O-N 3.18Å; V395-Q398 PolarHBondContact O-N 2.95Å; L396-Q398 VanDerWaalsContact C-N 3.33Å; Q398-A401 PolarHBondContact O-N 3.29Å; Q398-I402 WeakPolarHBondContact O-CA 3.43Å; Q398-I402 WeakPolarHBondContact O-CB 3.41Å; Q398-I402 WeakPolarHBondContact O-CD1 3.45Å; Q398-I402 WeakPolarHBondContact O-CG1 3.48Å; Q398-I402 PolarHBondContact O-N 3.13Å
399L38.1Very low33.3Very low89 Ų89101 Ų10147%0.46648%0.476SS..Hα-helixtrans-66.2-34.8162.6-74.3166.7000110.2V395 L396 I402 S403V395-L399 HydrophobicContact CG1-CD1 4.36Å; V395-L399 WeakPolarHBondContact O-CB 3.35Å; V395-L399 WeakPolarHBondContact O-CG 3.47Å; V395-L399 PolarHBondContact O-N 3.36Å; L396-L399 CarbonylContact O-C 3.09Å; L399-I402 CarbonylContact O-C 3.59Å; L399-S403 VanDerWaalsContact O-CB 3.26Å; L399-S403 WeakPolarHBondContact O-CB 3.09Å; L399-S403 PolarHBondContact O-N 3.16Å
400E37.4Very low32.9Very low73 Ų7396.5 Ų96.534%0.34147%0.474SS..Hα-helixtrans-87.1-19.1176.2-171.1-171.6-168.500111.6L396 E397 S403 R404L396-E400 WeakPolarHBondContact O-CA 3.45Å; L396-E400 WeakPolarHBondContact O-CB 3.47Å; L396-E400 PolarHBondContact O-N 2.95Å; E397-E400 CarbonylContact O-C 3.5Å; E400-S403 WeakPolarHBondContact CA-OG 3.28Å; E400-S403 WeakPolarHBondContact CG-OG 3.31Å; E400-S403 CarbonylContact O-C 3.55Å; E400-S403 PolarHBondContact O-N 3.37Å; E400-S403 PolarHBondContact O-OG 3.33Å; E400-R404 HydrophobicContact CG-CG 3.88Å; E400-R404 VanDerWaalsContact O-CA 3.26Å; E400-R404 WeakPolarHBondContact O-CA 3.45Å; E400-R404 WeakPolarHBondContact O-CB 3.4Å; E400-R404 WeakPolarHBondContact O-CD 3.25Å; E400-R404 WeakPolarHBondContact O-CG 3.23Å; E400-R404 PolarHBondContact O-N 3Å; E400-R404 IonicContact OE1-CZ 3.81Å; E400-R404 IonicContact OE1-NE 3.51Å; E400-R404 PolarHBondContact OE1-NE 3.35Å; E400-R404 IonicContact OE1-NH2 3.82Å; E400-R404 PolarHBondContact OE1-NH2 2.92Å; E400-R404 IonicContact OE2-CZ 2.72Å; E400-R404 IonicContact OE2-NE 3.3Å; E400-R404 IonicContact OE2-NH2 2.97Å; E400-R404 PolarHBondContact OE2-NH2 2.87Å; E400-R404 VanDerWaalsContact OE2-NH2 3.07Å
401A33.8Very low32.8Very low41 Ų4197.5 Ų97.534%0.33949%0.485SS..Hα-helixtrans-86.5-27.216500000110.5E397 Q398 R404 M405E397-A401 WeakPolarHBondContact O-CA 3.42Å; E397-A401 WeakPolarHBondContact O-CB 3.14Å; E397-A401 PolarHBondContact O-N 3.32Å; Q398-A401 PolarHBondContact O-N 3.29Å; A401-R404 CarbonylContact O-C 3.27Å; A401-M405 VanDerWaalsContact O-CA 3.3Å; A401-M405 WeakPolarHBondContact O-CA 3.5Å; A401-M405 WeakPolarHBondContact O-CB 3.16Å; A401-M405 WeakPolarHBondContact O-CG 3.48Å; A401-M405 PolarHBondContact O-N 3.41Å
402I34.7Very low32.6Very low71 Ų7197.8 Ų97.836%0.36449%0.486SS..Hα-helixtrans-67.6-29.4162.3-70.1162.9000108.8Q398 L399 T416Q398-I402 WeakPolarHBondContact O-CA 3.43Å; Q398-I402 WeakPolarHBondContact O-CB 3.41Å; Q398-I402 WeakPolarHBondContact O-CD1 3.45Å; Q398-I402 WeakPolarHBondContact O-CG1 3.48Å; Q398-I402 PolarHBondContact O-N 3.13Å; L399-I402 CarbonylContact O-C 3.59Å; I402-T416 HydrophobicContact CG2-CG2 3.85Å
403S32.7Very low32.5Very low44 Ų4498.4 Ų98.431%0.30849%0.492SS..Hα-helixtrans-85.2-28.7171.189.60000115.3L399 E400 L412L399-S403 VanDerWaalsContact O-CB 3.26Å; L399-S403 WeakPolarHBondContact O-CB 3.09Å; L399-S403 PolarHBondContact O-N 3.16Å; E400-S403 WeakPolarHBondContact CA-OG 3.28Å; E400-S403 WeakPolarHBondContact CG-OG 3.31Å; E400-S403 CarbonylContact O-C 3.55Å; E400-S403 PolarHBondContact O-N 3.37Å; E400-S403 PolarHBondContact O-OG 3.33Å; S403-L412 VanDerWaalsContact CB-CG 3.48Å
404R28.6Very low32.8Very low142 Ų14294.5 Ų94.554%0.53648%0.483SS..Hα-helixtrans-97.62.6177.9-70.2169.7-177.8173.75.2110.6E400 A401 Q406E400-R404 HydrophobicContact CG-CG 3.88Å; E400-R404 VanDerWaalsContact O-CA 3.26Å; E400-R404 WeakPolarHBondContact O-CA 3.45Å; E400-R404 WeakPolarHBondContact O-CB 3.4Å; E400-R404 WeakPolarHBondContact O-CD 3.25Å; E400-R404 WeakPolarHBondContact O-CG 3.23Å; E400-R404 PolarHBondContact O-N 3Å; E400-R404 IonicContact OE1-CZ 3.81Å; E400-R404 IonicContact OE1-NE 3.51Å; E400-R404 PolarHBondContact OE1-NE 3.35Å; E400-R404 IonicContact OE1-NH2 3.82Å; E400-R404 PolarHBondContact OE1-NH2 2.92Å; E400-R404 IonicContact OE2-CZ 2.72Å; E400-R404 IonicContact OE2-NE 3.3Å; E400-R404 IonicContact OE2-NH2 2.97Å; E400-R404 PolarHBondContact OE2-NH2 2.87Å; E400-R404 VanDerWaalsContact OE2-NH2 3.07Å; A401-R404 CarbonylContact O-C 3.27Å; R404-Q406 WeakPolarHBondContact O-CG 3.17Å; R404-Q406 PolarHBondContact O-N 3.19Å
405M27.2Very low32.6Very low77 Ų7794 Ų9438%0.37948%0.479SS..SBendtrans-59.693.9161.4-99.6176.5-157.600103.7L126 A401 V407L126-M405 HydrophobicContact CB-CE 3.57Å; L126-M405 HydrophobicContact CD1-CE 4.14Å; L126-M405 HydrophobicContact CD2-CE 3.46Å; L126-M405 VanDerWaalsContact CD2-CE 3.46Å; L126-M405 HydrophobicContact CG-CE 3.88Å; A401-M405 VanDerWaalsContact O-CA 3.3Å; A401-M405 WeakPolarHBondContact O-CA 3.5Å; A401-M405 WeakPolarHBondContact O-CB 3.16Å; A401-M405 WeakPolarHBondContact O-CG 3.48Å; A401-M405 PolarHBondContact O-N 3.41Å; M405-V407 PolarHBondContact O-N 2.99Å
406Q25.2Very low32.9Very low184 Ų18495 Ų9586%0.8649%0.486SS*.  trans-67.943.4-173.7-78.6-176.2-14.600111.1R404 R408R404-Q406 WeakPolarHBondContact O-CG 3.17Å; R404-Q406 PolarHBondContact O-N 3.19Å; Q406-R408 PolarHBondContact O-N 3.1Å
407V27Very low33.2Very low57 Ų5792.5 Ų92.535%0.34547%0.473SS..SBendtrans-65.9111.1146.9-161.90000103.9K129 M405 F409K129-V407 HydrophobicContact CD-CG2 4.4Å; M405-V407 PolarHBondContact O-N 2.99Å; V407-F409 HydrophobicContact CB-CD2 4.08Å; V407-F409 HydrophobicContact CB-CE2 4.49Å; V407-F409 HydrophobicContact CG1-CD2 3.46Å; V407-F409 VanDerWaalsContact CG1-CD2 3.46Å; V407-F409 HydrophobicContact CG1-CE2 3.42Å; V407-F409 VanDerWaalsContact CG1-CE2 3.42Å; V407-F409 PolarHBondContact O-N 3.48Å
408R26.2Very low33.5Very low245 Ų24591.4 Ų91.493%0.92547%0.466SS*.SBendtrans-57.268.6-178.5-74.6-178.6175.7170.6-3.4112.5Q406Q406-R408 PolarHBondContact O-N 3.1Å
409F27.2Very low33.7Very low163 Ų16392 Ų9272%0.71547%0.467SS*.  trans-121.386.8167-68.5-65.4000104.6V407 H411V407-F409 HydrophobicContact CB-CD2 4.08Å; V407-F409 HydrophobicContact CB-CE2 4.49Å; V407-F409 HydrophobicContact CG1-CD2 3.46Å; V407-F409 VanDerWaalsContact CG1-CD2 3.46Å; V407-F409 HydrophobicContact CG1-CE2 3.42Å; V407-F409 VanDerWaalsContact CG1-CE2 3.42Å; V407-F409 PolarHBondContact O-N 3.48Å; F409-H411 PolarHBondContact O-N 2.87Å
410G24.7Very low34.2Very low76 Ų7689.9 Ų89.978%0.78445%0.453SS*.  trans-56.1133.6176.200000109.7
411H31.1Very low34.6Very low180 Ų18086.8 Ų86.883%0.83344%0.44SS*.SBendtrans70116.6-168.9-77.4-84.2000114.4F409 S413F409-H411 PolarHBondContact O-N 2.87Å; H411-S413 PolarHBondContact O-N 3.19Å
412L32.7Very low35.2Very low125 Ų12585.1 Ų85.165%0.65443%0.425SS*.  trans-39.591.2159.2-94.3138.1000108.9S403S403-L412 VanDerWaalsContact CB-CG 3.48Å
413S40.1Very low35.9Very low35 Ų3583.9 Ų83.925%0.24543%0.425CS..  trans-74.5143.3168.758.90000105.8H411 V415H411-S413 PolarHBondContact O-N 3.19Å; S413-V415 PolarHBondContact O-N 2.83Å; S413-V415 WeakPolarHBondContact OG-CB 3.17Å; S413-V415 WeakPolarHBondContact OG-CG2 2.91Å
414D39.3Very low36.6Very low67 Ų6782.2 Ų82.236%0.35841%0.414SS..THydrogen-bonded Turntrans-48.62.7169.7-60-83.2000114.8F205 Y418F205-D414 HydrophobicContact CD1-CB 3.14Å; F205-D414 WeakPolarHBondContact CD1-OD2 3.47Å; F205-D414 HydrophobicContact CE1-CB 3.13Å; F205-D414 HydrophobicContact CG-CB 3.92Å; F205-D414 HydrophobicContact CZ-CB 3.96Å; D414-Y418 WeakPolarHBondContact O-CA 3.44Å; D414-Y418 WeakPolarHBondContact O-CB 3.45Å; D414-Y418 PolarHBondContact O-N 3.46Å
415V35.1Very low37.5Very low48 Ų4875.6 Ų75.629%0.29139%0.39SS..Hα-helixtrans-60.1-47.7176176.60000113.1S413 L417 Y418 W419S413-V415 PolarHBondContact O-N 2.83Å; S413-V415 WeakPolarHBondContact OG-CB 3.17Å; S413-V415 WeakPolarHBondContact OG-CG2 2.91Å; V415-L417 VanDerWaalsContact C-N 3.31Å; V415-L417 PolarHBondContact O-N 3.4Å; V415-Y418 CarbonylContact O-C 3.54Å; V415-Y418 WeakPolarHBondContact O-CB 3.13Å; V415-Y418 PolarHBondContact O-N 2.91Å; V415-W419 PolarHBondContact O-N 3.24Å
416T40.4Very low38.4Very low75 Ų7573.8 Ų73.846%0.4638%0.381SS..Hα-helixtrans-68.8-35.7-178.9-43.80000112.1I402 W419 F420I402-T416 HydrophobicContact CG2-CG2 3.85Å; T416-W419 WeakPolarHBondContact O-CB 3.37Å; T416-W419 PolarHBondContact O-N 3.27Å; T416-F420 PolarHBondContact O-N 3.38Å
417L43.6Very low39.4Very low38 Ų3865.3 Ų65.320%0.19934%0.341CS..Hα-helixtrans-71.3-41.1173.7-178.463.8000111.2L287 M291 V415 W419 F420 V421L287-L417 HydrophobicContact CB-CD2 4.31Å; L287-L417 HydrophobicContact CD1-CD1 3.69Å; L287-L417 HydrophobicContact CD1-CD2 3.38Å; L287-L417 HydrophobicContact CD1-CG 3.48Å; L287-L417 VanDerWaalsContact CD1-CG 3.48Å; L287-L417 HydrophobicContact CD2-CD1 3.54Å; L287-L417 HydrophobicContact CD2-CD2 3.07Å; L287-L417 HydrophobicContact CD2-CG 3.75Å; L287-L417 HydrophobicContact CG-CD1 4.05Å; L287-L417 HydrophobicContact CG-CD2 3.61Å; L287-L417 HydrophobicContact CG-CG 4.09Å; M291-L417 HydrophobicContact CE-CD1 3.64Å; V415-L417 VanDerWaalsContact C-N 3.31Å; V415-L417 PolarHBondContact O-N 3.4Å; L417-W419 VanDerWaalsContact C-N 3.31Å; L417-W419 PolarHBondContact O-N 2.91Å; L417-F420 CarbonylContact O-C 3.6Å; L417-F420 WeakPolarHBondContact O-CA 3.43Å; L417-F420 WeakPolarHBondContact O-CB 3.5Å; L417-F420 PolarHBondContact O-N 3.37Å; L417-V421 VanDerWaalsContact O-CG2 3.32Å; L417-V421 WeakPolarHBondContact O-CG2 3.19Å; L417-V421 PolarHBondContact O-N 2.8Å
418Y42Very low40.3Very low36 Ų3663.1 Ų63.114%0.14133%0.327CS..Hα-helixtrans-57.3-44.4169.6175-95.2000109.9T138 I197 D414 V415 F420 V421 L422T138-Y418 PolarHBondContact OG1-OH 3.13Å; I197-Y418 HydrophobicContact CG2-CD2 3.77Å; I197-Y418 HydrophobicContact CG2-CE2 3.44Å; I197-Y418 VanDerWaalsContact CG2-CE2 3.44Å; D414-Y418 WeakPolarHBondContact O-CA 3.44Å; D414-Y418 WeakPolarHBondContact O-CB 3.45Å; D414-Y418 PolarHBondContact O-N 3.46Å; V415-Y418 CarbonylContact O-C 3.54Å; V415-Y418 WeakPolarHBondContact O-CB 3.13Å; V415-Y418 PolarHBondContact O-N 2.91Å; Y418-F420 VanDerWaalsContact C-N 3.26Å; Y418-F420 PolarHBondContact O-N 2.9Å; Y418-V421 PolarHBondContact O-N 3.47Å; Y418-L422 HydrophobicContact CD1-CD2 4.19Å; Y418-L422 HydrophobicContact CE1-CD2 3.61Å; Y418-L422 HydrophobicContact CE1-CG 4.5Å; Y418-L422 WeakPolarHBondContact O-CA 3.49Å; Y418-L422 WeakPolarHBondContact O-CB 3.46Å; Y418-L422 PolarHBondContact O-N 3.24Å
419W40.8Very low41.3Very low67 Ų6752.1 Ų52.125%0.25429%0.287SS..Hα-helixtrans-57.1-40.8172.5-77.8111.7000111.8T132 G134 L137 V415 T416 L417 A423T132-W419 WeakPolarHBondContact O-CH2 3.5Å; T132-W419 WeakPolarHBondContact O-CZ2 3.44Å; G134-W419 VanDerWaalsContact CA-CZ2 3.44Å; L137-W419 HydrophobicContact CB-CH2 3.74Å; L137-W419 HydrophobicContact CB-CZ3 3.83Å; L137-W419 HydrophobicContact CD2-CE3 3.6Å; L137-W419 HydrophobicContact CD2-CH2 3.97Å; L137-W419 HydrophobicContact CD2-CZ3 3.13Å; L137-W419 HydrophobicContact CG-CH2 4.45Å; L137-W419 HydrophobicContact CG-CZ3 4.02Å; V415-W419 PolarHBondContact O-N 3.24Å; T416-W419 WeakPolarHBondContact O-CB 3.37Å; T416-W419 PolarHBondContact O-N 3.27Å; L417-W419 VanDerWaalsContact C-N 3.31Å; L417-W419 PolarHBondContact O-N 2.91Å; W419-A423 WeakPolarHBondContact O-CB 3.43Å; W419-A423 PolarHBondContact O-N 3.42Å
420F47.7Very low42.1Very low43 Ų4345.1 Ų45.119%0.18926%0.257CS..Hα-helixtrans-69.5-46.6178.9-159.6-63.4000111.6W118 L263 L267 T416 L417 Y418 L422 A423 A424W118-F420 HydrophobicContact CH2-CD2 4.07Å; W118-F420 AromaticContact CH2-CE2 3.16Å; W118-F420 HydrophobicContact CH2-CE2 3.16Å; W118-F420 AromaticContact CH2-CZ 3.72Å; W118-F420 HydrophobicContact CH2-CZ 3.72Å; W118-F420 HydrophobicContact CZ2-CE2 4.08Å; W118-F420 HydrophobicContact CZ2-CZ 4.22Å; W118-F420 AromaticContact CZ3-CE2 3.6Å; W118-F420 HydrophobicContact CZ3-CE2 3.6Å; W118-F420 HydrophobicContact CZ3-CZ 4.3Å; L263-F420 HydrophobicContact CD1-CD1 3.94Å; L263-F420 HydrophobicContact CD1-CE1 3.14Å; L263-F420 HydrophobicContact CD1-CE2 4.41Å; L263-F420 HydrophobicContact CD1-CZ 3.46Å; L263-F420 VanDerWaalsContact CD1-CZ 3.46Å; L263-F420 HydrophobicContact CD2-CE1 4.49Å; L263-F420 HydrophobicContact CG-CE1 3.71Å; L263-F420 HydrophobicContact CG-CZ 4.27Å; L267-F420 HydrophobicContact CD1-CD1 4.3Å; L267-F420 HydrophobicContact CD1-CE1 3.81Å; L267-F420 HydrophobicContact CD2-CD1 3.51Å; L267-F420 HydrophobicContact CD2-CE1 3.17Å; L267-F420 HydrophobicContact CD2-CG 4.47Å; L267-F420 HydrophobicContact CD2-CZ 3.84Å; L267-F420 HydrophobicContact CG-CD1 4.03Å; L267-F420 HydrophobicContact CG-CE1 3.29Å; L267-F420 HydrophobicContact CG-CZ 3.96Å; T416-F420 PolarHBondContact O-N 3.38Å; L417-F420 CarbonylContact O-C 3.6Å; L417-F420 WeakPolarHBondContact O-CA 3.43Å; L417-F420 WeakPolarHBondContact O-CB 3.5Å; L417-F420 PolarHBondContact O-N 3.37Å; Y418-F420 VanDerWaalsContact C-N 3.26Å; Y418-F420 PolarHBondContact O-N 2.9Å; F420-L422 VanDerWaalsContact C-N 3.32Å; F420-A423 WeakPolarHBondContact O-CB 3.33Å; F420-A423 PolarHBondContact O-N 2.86Å; F420-A424 WeakPolarHBondContact O-CB 3.42Å; F420-A424 PolarHBondContact O-N 3.38Å
421V46.2Very low43Very low9 Ų941.6 Ų41.66%0.05522%0.22CC..Hα-helixtrans-71.1-32.5178.5-166.20000110.8I197 L287 L417 Y418 A424 L425I197-V421 HydrophobicContact CD1-CB 4.05Å; I197-V421 HydrophobicContact CD1-CG1 3.1Å; L287-V421 HydrophobicContact CD1-CG2 4.09Å; L417-V421 VanDerWaalsContact O-CG2 3.32Å; L417-V421 WeakPolarHBondContact O-CG2 3.19Å; L417-V421 PolarHBondContact O-N 2.8Å; Y418-V421 PolarHBondContact O-N 3.47Å; V421-A424 CarbonylContact O-C 3.57Å; V421-A424 VanDerWaalsContact O-CB 3.32Å; V421-A424 WeakPolarHBondContact O-CB 3.22Å; V421-A424 PolarHBondContact O-N 2.64Å; V421-L425 VanDerWaalsContact O-CB 3.27Å; V421-L425 WeakPolarHBondContact O-CB 3.39Å; V421-L425 VanDerWaalsContact O-CG 3.31Å; V421-L425 WeakPolarHBondContact O-CG 3.21Å; V421-L425 PolarHBondContact O-N 3.33Å
422L47.5Very low43.7Very low5 Ų533.2 Ų33.23%0.02618%0.182CC..Hα-helixtrans-69.7-38.6173.7-167.969000111.4L137 I141 Y418 F420 L425 L426L137-L422 HydrophobicContact CD2-CD2 3.33Å; L137-L422 HydrophobicContact CD2-CG 4.15Å; L137-L422 HydrophobicContact CG-CD2 3.9Å; I141-L422 HydrophobicContact CD1-CD1 3.28Å; I141-L422 HydrophobicContact CD1-CD2 3.57Å; I141-L422 HydrophobicContact CD1-CG 3.34Å; Y418-L422 HydrophobicContact CD1-CD2 4.19Å; Y418-L422 HydrophobicContact CE1-CD2 3.61Å; Y418-L422 HydrophobicContact CE1-CG 4.5Å; Y418-L422 WeakPolarHBondContact O-CA 3.49Å; Y418-L422 WeakPolarHBondContact O-CB 3.46Å; Y418-L422 PolarHBondContact O-N 3.24Å; F420-L422 VanDerWaalsContact C-N 3.32Å; L422-L425 HydrophobicContact CD1-CD1 4.43Å; L422-L425 WeakPolarHBondContact O-CB 3.45Å; L422-L425 PolarHBondContact O-N 2.86Å; L422-L426 WeakPolarHBondContact O-CB 3.35Å; L422-L426 PolarHBondContact O-N 3.13Å
423A48Very low44.1Very low45 Ų4529.5 Ų29.537%0.37216%0.159SC..Hα-helixtrans-61.4-49.416800000109W419 F420 L425 L426 F427W419-A423 WeakPolarHBondContact O-CB 3.43Å; W419-A423 PolarHBondContact O-N 3.42Å; F420-A423 WeakPolarHBondContact O-CB 3.33Å; F420-A423 PolarHBondContact O-N 2.86Å; A423-L425 PolarHBondContact O-N 3.1Å; A423-L425 VanDerWaalsContact O-N 3.17Å; A423-L426 PolarHBondContact O-N 3.27Å; A423-F427 WeakPolarHBondContact O-CA 3.35Å; A423-F427 WeakPolarHBondContact O-CB 3.13Å; A423-F427 PolarHBondContact O-N 2.84Å
424A48.5Very low44Very low10 Ų1030.6 Ų30.68%0.08316%0.161CC..Hα-helixtrans-54.2-35.4174.100000113.5L263 F420 V421 F427 F428L263-A424 HydrophobicContact CD2-CB 3.3Å; L263-A424 HydrophobicContact CG-CB 4.45Å; F420-A424 WeakPolarHBondContact O-CB 3.42Å; F420-A424 PolarHBondContact O-N 3.38Å; V421-A424 CarbonylContact O-C 3.57Å; V421-A424 VanDerWaalsContact O-CB 3.32Å; V421-A424 WeakPolarHBondContact O-CB 3.22Å; V421-A424 PolarHBondContact O-N 2.64Å; A424-F427 WeakPolarHBondContact O-CB 3.35Å; A424-F428 WeakPolarHBondContact O-CB 3.31Å; A424-F428 PolarHBondContact O-N 3.05Å
425L47.2Very low44.2Very low3 Ų330.5 Ų30.52%0.01616%0.156CC..Hα-helixtrans-74.1-53.9179-91.2-179.5000113.9V193 L194 I197 V421 L422 A423 F427 F428 V429V193-L425 HydrophobicContact CB-CD2 3.44Å; V193-L425 VanDerWaalsContact CB-CD2 3.44Å; V193-L425 HydrophobicContact CG1-CD2 3.64Å; V193-L425 WeakPolarHBondContact O-CD2 3.48Å; L194-L425 HydrophobicContact CB-CD2 4.31Å; L194-L425 HydrophobicContact CD1-CB 3.72Å; L194-L425 HydrophobicContact CD1-CD2 4.03Å; L194-L425 HydrophobicContact CD1-CG 4.42Å; L194-L425 WeakPolarHBondContact CD1-O 3.48Å; L194-L425 HydrophobicContact CG-CB 4.21Å; L194-L425 HydrophobicContact CG-CD1 4.43Å; L194-L425 HydrophobicContact CG-CD2 4.21Å; I197-L425 HydrophobicContact CB-CD1 3.47Å; I197-L425 VanDerWaalsContact CB-CD1 3.47Å; I197-L425 HydrophobicContact CD1-CD1 3.32Å; I197-L425 HydrophobicContact CD1-CG 3.95Å; I197-L425 HydrophobicContact CG1-CD1 3.75Å; I197-L425 HydrophobicContact CG2-CD1 3.94Å; V421-L425 VanDerWaalsContact O-CB 3.27Å; V421-L425 WeakPolarHBondContact O-CB 3.39Å; V421-L425 VanDerWaalsContact O-CG 3.31Å; V421-L425 WeakPolarHBondContact O-CG 3.21Å; V421-L425 PolarHBondContact O-N 3.33Å; L422-L425 HydrophobicContact CD1-CD1 4.43Å; L422-L425 WeakPolarHBondContact O-CB 3.45Å; L422-L425 PolarHBondContact O-N 2.86Å; A423-L425 PolarHBondContact O-N 3.1Å; A423-L425 VanDerWaalsContact O-N 3.17Å; L425-F427 PolarHBondContact O-N 3.39Å; L425-F428 WeakPolarHBondContact O-CB 3.34Å; L425-F428 PolarHBondContact O-N 3.46Å; L425-F428 VanDerWaalsContact O-N 3.08Å; L425-V429 PolarHBondContact O-N 2.73Å
426L46.7Very low44.5Very low38 Ų3829.4 Ų29.420%0.19915%0.149CC..Hα-helixtrans-52-43.7172.4-92.9166.8000109.4L137 I141 L422 A423 V429 L430L137-L426 HydrophobicContact CD1-CD1 4.38Å; L137-L426 HydrophobicContact CD2-CD1 4.33Å; I141-L426 HydrophobicContact CD1-CD1 3.71Å; I141-L426 HydrophobicContact CD1-CD2 4.38Å; I141-L426 HydrophobicContact CD1-CG 3.83Å; I141-L426 HydrophobicContact CG1-CD1 4.05Å; I141-L426 HydrophobicContact CG1-CD2 4Å; I141-L426 HydrophobicContact CG1-CG 4.01Å; L422-L426 WeakPolarHBondContact O-CB 3.35Å; L422-L426 PolarHBondContact O-N 3.13Å; A423-L426 PolarHBondContact O-N 3.27Å; L426-V429 PolarHBondContact O-N 3.46Å; L426-L430 VanDerWaalsContact O-CD1 3.25Å; L426-L430 WeakPolarHBondContact O-CD1 3.36Å; L426-L430 VanDerWaalsContact O-CG 3.26Å; L426-L430 WeakPolarHBondContact O-CG 3.43Å; L426-L430 PolarHBondContact O-N 3.19Å
427F45.2Very low44.6Very low6 Ų631.7 Ų31.73%0.02615%0.15CC..Hα-helixtrans-62.9-43.1179.1-170.7-86.7000113.1F256 L259 R260 A423 A424 L425 L430 T431F256-F427 HydrophobicContact CB-CZ 4.36Å; F256-F427 HydrophobicContact CD1-CD2 4.36Å; F256-F427 AromaticContact CD1-CE2 3.88Å; F256-F427 HydrophobicContact CD1-CE2 3.88Å; F256-F427 HydrophobicContact CD1-CZ 4.41Å; F256-F427 WeakPolarHBondContact O-CE1 3.1Å; F256-F427 WeakPolarHBondContact O-CZ 3.34Å; L259-F427 HydrophobicContact CB-CD2 3.87Å; L259-F427 HydrophobicContact CB-CE2 3.16Å; L259-F427 HydrophobicContact CB-CZ 3.63Å; L259-F427 HydrophobicContact CD1-CD2 4.5Å; L259-F427 HydrophobicContact CD2-CD2 3.09Å; L259-F427 HydrophobicContact CD2-CE2 3.26Å; L259-F427 HydrophobicContact CD2-CG 4.16Å; L259-F427 HydrophobicContact CD2-CZ 4.4Å; L259-F427 HydrophobicContact CG-CD2 3.21Å; L259-F427 HydrophobicContact CG-CE2 3.09Å; L259-F427 HydrophobicContact CG-CG 4.02Å; L259-F427 HydrophobicContact CG-CZ 3.83Å; R260-F427 HydrophobicContact CB-CD1 4.13Å; R260-F427 HydrophobicContact CB-CE1 3.09Å; R260-F427 HydrophobicContact CB-CZ 3.56Å; R260-F427 HydrophobicContact CG-CD1 4.18Å; R260-F427 HydrophobicContact CG-CE1 3.5Å; R260-F427 VanDerWaalsContact CG-CE1 3.5Å; R260-F427 HydrophobicContact CG-CZ 4.44Å; A423-F427 WeakPolarHBondContact O-CA 3.35Å; A423-F427 WeakPolarHBondContact O-CB 3.13Å; A423-F427 PolarHBondContact O-N 2.84Å; A424-F427 WeakPolarHBondContact O-CB 3.35Å; L425-F427 PolarHBondContact O-N 3.39Å; F427-L430 PolarHBondContact O-N 3.42Å; F427-T431 VanDerWaalsContact CE1-OG1 3.23Å; F427-T431 WeakPolarHBondContact CE1-OG1 3.17Å; F427-T431 PolarHBondContact O-N 3.11Å; F427-T431 VanDerWaalsContact O-N 3.11Å; F427-T431 PolarHBondContact O-OG1 3.03Å
428F46.7Very low44.3Very low11 Ų1139 Ų395%0.04818%0.175CC..Hα-helixtrans-63.5-48175.2-176.2-109.4000111.9Y105 V193 H297 A298 A424 L425 L430 T431 L432Y105-F428 HydrophobicContact CE1-CE2 4.27Å; Y105-F428 HydrophobicContact CE1-CZ 4.19Å; V193-F428 HydrophobicContact CB-CD1 4.39Å; V193-F428 HydrophobicContact CG2-CD1 4.13Å; V193-F428 HydrophobicContact CG2-CE1 3.9Å; H297-F428 AromaticContact CE1-CZ 3.31Å; H297-F428 WeakPolarHBondContact CE1-CZ 3.31Å; H297-F428 AromaticContact ND1-CE2 3.79Å; H297-F428 AromaticContact ND1-CZ 3.39Å; H297-F428 WeakPolarHBondContact ND1-CZ 3.49Å; H297-F428 AromaticContact NE2-CZ 3.99Å; A298-F428 HydrophobicContact CB-CD2 4.35Å; A298-F428 HydrophobicContact CB-CE2 4.43Å; A424-F428 WeakPolarHBondContact O-CB 3.31Å; A424-F428 PolarHBondContact O-N 3.05Å; L425-F428 WeakPolarHBondContact O-CB 3.34Å; L425-F428 PolarHBondContact O-N 3.46Å; L425-F428 VanDerWaalsContact O-N 3.08Å; F428-L430 PolarHBondContact O-N 3.45Å; F428-T431 PolarHBondContact O-N 3.16Å; F428-L432 HydrophobicContact CD1-CD1 3.58Å; F428-L432 HydrophobicContact CD2-CD1 4.28Å; F428-L432 HydrophobicContact CE1-CD1 3.28Å; F428-L432 HydrophobicContact CE1-CG 4.46Å; F428-L432 HydrophobicContact CE2-CD1 4Å; F428-L432 HydrophobicContact CE2-CD2 4.47Å; F428-L432 HydrophobicContact CE2-CG 4.44Å; F428-L432 HydrophobicContact CG-CD1 4.06Å; F428-L432 HydrophobicContact CZ-CD1 3.46Å; F428-L432 VanDerWaalsContact CZ-CD1 3.46Å; F428-L432 HydrophobicContact CZ-CD2 4.2Å; F428-L432 HydrophobicContact CZ-CG 4.24Å; F428-L432 VanDerWaalsContact O-CD1 3.23Å; F428-L432 WeakPolarHBondContact O-CD1 3.34Å; F428-L432 WeakPolarHBondContact O-CG 3.22Å; F428-L432 PolarHBondContact O-N 3.12Å
429V47.2Very low44.2Very low14 Ų1445.5 Ų45.59%0.08520%0.203CC..Hα-helixtrans-57.4-36.3179.4152.10000112.4L194 L425 L426L194-V429 HydrophobicContact CB-CG2 4.31Å; L194-V429 HydrophobicContact CD1-CB 3.89Å; L194-V429 HydrophobicContact CD1-CG2 3.28Å; L194-V429 HydrophobicContact CG-CG2 4.28Å; L425-V429 PolarHBondContact O-N 2.73Å; L426-V429 PolarHBondContact O-N 3.46Å
430L43.4Very low44.2Very low16 Ų1645.5 Ų45.58%0.08421%0.208CC..Hα-helixtrans-84.3-30.6-176.6-65.3160.8000113.3F243 F256 L426 F427 F428 L432 R433F243-L430 HydrophobicContact CB-CD1 4.01Å; F243-L430 HydrophobicContact CB-CD2 4.34Å; F243-L430 HydrophobicContact CD1-CD1 3.39Å; F243-L430 HydrophobicContact CD2-CD1 3.43Å; F243-L430 VanDerWaalsContact CD2-CD1 3.43Å; F243-L430 HydrophobicContact CE1-CD1 3.48Å; F243-L430 VanDerWaalsContact CE1-CD1 3.48Å; F243-L430 HydrophobicContact CE2-CD1 3.55Å; F243-L430 HydrophobicContact CG-CD1 3.32Å; F243-L430 HydrophobicContact CZ-CD1 3.54Å; F256-L430 HydrophobicContact CD1-CB 3.4Å; F256-L430 VanDerWaalsContact CD1-CB 3.4Å; F256-L430 HydrophobicContact CD1-CD1 4.4Å; F256-L430 HydrophobicContact CD2-CB 4.29Å; F256-L430 HydrophobicContact CE1-CB 2.96Å; F256-L430 HydrophobicContact CE1-CD1 3.34Å; F256-L430 HydrophobicContact CE1-CD2 4.32Å; F256-L430 HydrophobicContact CE1-CG 3.67Å; F256-L430 HydrophobicContact CE2-CB 3.87Å; F256-L430 HydrophobicContact CG-CB 4.06Å; F256-L430 HydrophobicContact CZ-CB 3.23Å; F256-L430 HydrophobicContact CZ-CD1 3.64Å; F256-L430 HydrophobicContact CZ-CD2 3.9Å; F256-L430 HydrophobicContact CZ-CG 3.77Å; L426-L430 VanDerWaalsContact O-CD1 3.25Å; L426-L430 WeakPolarHBondContact O-CD1 3.36Å; L426-L430 VanDerWaalsContact O-CG 3.26Å; L426-L430 WeakPolarHBondContact O-CG 3.43Å; L426-L430 PolarHBondContact O-N 3.19Å; F427-L430 PolarHBondContact O-N 3.42Å; F428-L430 PolarHBondContact O-N 3.45Å; L430-L432 VanDerWaalsContact C-N 3.26Å; L430-L432 PolarHBondContact O-N 3.32Å; L430-R433 PolarHBondContact O-N 3.31Å
431T43.1Very low43.9Very low2 Ų251.3 Ų51.31%0.01223%0.233CC..Hα-helixtrans-64.8-33.6176.5-49.20000112.5F256 R260 F427 F428 R433 M434F256-T431 HydrophobicContact CB-CG2 4.29Å; F256-T431 WeakPolarHBondContact O-CG2 3.32Å; F256-T431 PolarHBondContact O-OG1 3.11Å; R260-T431 VanDerWaalsContact NH2-CG2 3.29Å; F427-T431 VanDerWaalsContact CE1-OG1 3.23Å; F427-T431 WeakPolarHBondContact CE1-OG1 3.17Å; F427-T431 PolarHBondContact O-N 3.11Å; F427-T431 VanDerWaalsContact O-N 3.11Å; F427-T431 PolarHBondContact O-OG1 3.03Å; F428-T431 PolarHBondContact O-N 3.16Å; T431-R433 VanDerWaalsContact C-N 3.35Å; T431-R433 PolarHBondContact O-N 3.33Å; T431-M434 PolarHBondContact O-N 3.17Å
432L45.4Very low43.9Very low5 Ų556 Ų563%0.02626%0.257CS..Hα-helixtrans-65.6-38.3-178.9-73.4158.8000112.4Y105 A190 F428 L430 M434 R435Y105-L432 HydrophobicContact CD2-CD2 3.76Å; Y105-L432 HydrophobicContact CE1-CD2 4.19Å; Y105-L432 HydrophobicContact CE2-CD2 2.99Å; Y105-L432 HydrophobicContact CE2-CG 4.5Å; Y105-L432 VanDerWaalsContact OH-CD2 3.24Å; Y105-L432 WeakPolarHBondContact OH-CD2 3.14Å; A190-L432 HydrophobicContact CB-CB 3.67Å; A190-L432 HydrophobicContact CB-CD2 3.92Å; A190-L432 HydrophobicContact CB-CG 4.25Å; A190-L432 WeakPolarHBondContact O-CB 3.4Å; A190-L432 WeakPolarHBondContact O-CD1 3.06Å; A190-L432 VanDerWaalsContact O-CG 3.27Å; A190-L432 WeakPolarHBondContact O-CG 3.39Å; F428-L432 HydrophobicContact CD1-CD1 3.58Å; F428-L432 HydrophobicContact CD2-CD1 4.28Å; F428-L432 HydrophobicContact CE1-CD1 3.28Å; F428-L432 HydrophobicContact CE1-CG 4.46Å; F428-L432 HydrophobicContact CE2-CD1 4Å; F428-L432 HydrophobicContact CE2-CD2 4.47Å; F428-L432 HydrophobicContact CE2-CG 4.44Å; F428-L432 HydrophobicContact CG-CD1 4.06Å; F428-L432 HydrophobicContact CZ-CD1 3.46Å; F428-L432 VanDerWaalsContact CZ-CD1 3.46Å; F428-L432 HydrophobicContact CZ-CD2 4.2Å; F428-L432 HydrophobicContact CZ-CG 4.24Å; F428-L432 VanDerWaalsContact O-CD1 3.23Å; F428-L432 WeakPolarHBondContact O-CD1 3.34Å; F428-L432 WeakPolarHBondContact O-CG 3.22Å; F428-L432 PolarHBondContact O-N 3.12Å; L430-L432 VanDerWaalsContact C-N 3.26Å; L430-L432 PolarHBondContact O-N 3.32Å; L432-M434 VanDerWaalsContact C-N 3.3Å; L432-M434 PolarHBondContact O-N 3.03Å; L432-R435 PolarHBondContact O-N 3.49Å
433R42.6Very low43.9Very low47 Ų4758.4 Ų58.418%0.17728%0.278CS..Hα-helixtrans-64.9-32.8176.4-165.8178.1-179.1165.33.1113V236 T240 L430 T431 R435V236-R433 PolarHBondContact O-NH1 3.43Å; V236-R433 PolarHBondContact O-NH2 3.33Å; T240-R433 WeakPolarHBondContact OG1-CD 3.12Å; T240-R433 PolarHBondContact OG1-NH1 2.73Å; L430-R433 PolarHBondContact O-N 3.31Å; T431-R433 VanDerWaalsContact C-N 3.35Å; T431-R433 PolarHBondContact O-N 3.33Å; R433-R435 PolarHBondContact O-N 2.7Å
434M38.3Very low44Very low58 Ų5859.8 Ų59.829%0.28628%0.282SS..Hα-helixtrans-67-34.1-178.5-75.7-64.2-9600113.6E244 F256 T431 L432E244-M434 WeakPolarHBondContact OE1-CE 3.38Å; F256-M434 HydrophobicContact CB-CG 4.27Å; F256-M434 HydrophobicContact CD2-CG 3.6Å; F256-M434 HydrophobicContact CD2-SD 4.42Å; F256-M434 HydrophobicContact CE2-CG 4.44Å; F256-M434 HydrophobicContact CG-CG 4.34Å; T431-M434 PolarHBondContact O-N 3.17Å; L432-M434 VanDerWaalsContact C-N 3.3Å; L432-M434 PolarHBondContact O-N 3.03Å
435R42.5Very low44Very low64 Ų6467.6 Ų67.624%0.24231%0.313CS..Hα-helixtrans-76.3-31.1-178.8-76.7-165.7-172.3178.34.5113.1P107 R110 E257 L432 R433 R437 R438P107-R435 VanDerWaalsContact CB-NH1 3.33Å; R110-R435 VanDerWaalsContact NE-NH2 3.13Å; E257-R435 IonicContact OE1-NE 3.79Å; E257-R435 PolarHBondContact OE1-NE 3.42Å; L432-R435 PolarHBondContact O-N 3.49Å; R433-R435 PolarHBondContact O-N 2.7Å; R435-R437 VanDerWaalsContact C-N 3.33Å; R435-R437 PolarHBondContact O-N 2.99Å; R435-R438 PolarHBondContact O-N 2.74Å; R435-R438 VanDerWaalsContact O-N 3.14Å
436V41.8Very low44.2Very low26 Ų2675.1 Ų75.116%0.15835%0.348CS..Hα-helixtrans-64.1-42.2177.7-167.90000110.3F183 I187 R438 K439F183-V436 HydrophobicContact CD2-CG1 3.95Å; F183-V436 HydrophobicContact CE2-CB 4.16Å; F183-V436 HydrophobicContact CE2-CG1 3.24Å; F183-V436 HydrophobicContact CZ-CB 4.28Å; F183-V436 HydrophobicContact CZ-CG1 3.71Å; I187-V436 HydrophobicContact CB-CG1 4.44Å; I187-V436 HydrophobicContact CD1-CG1 4.05Å; I187-V436 HydrophobicContact CG1-CB 3.97Å; I187-V436 HydrophobicContact CG1-CG1 3.24Å; I187-V436 HydrophobicContact CG1-CG2 4.06Å; V436-R438 PolarHBondContact O-N 3.26Å; V436-K439 PolarHBondContact O-N 3.11Å
437R41.3Very low44.2Very low123 Ų12380.9 Ų80.946%0.46437%0.372SS..Hα-helixtrans-62.9-23175.2-76.8-174.5170170.4-3.9114.8F183 R435F183-R437 HydrophobicContact CZ-CG 4.24Å; R435-R437 VanDerWaalsContact C-N 3.33Å; R435-R437 PolarHBondContact O-N 2.99Å
438R39.3Very low44.1Very low192 Ų19290.9 Ų90.973%0.72542%0.421SS*.Hα-helixtrans-82.3-28.3-176.1-132.1-178.3-163.3-178.95.3112.8R435 V436 D440R435-R438 PolarHBondContact O-N 2.74Å; R435-R438 VanDerWaalsContact O-N 3.14Å; V436-R438 PolarHBondContact O-N 3.26Å; R438-D440 VanDerWaalsContact C-N 3.27Å; R438-D440 PolarHBondContact O-N 3.15Å
439K39.8Very low43.9Very low171 Ų17194.9 Ų94.974%0.74344%0.44SS*.Hα-helixtrans-64.1-34.6175.5-82.8-170.3173.4-177.70111.5V436 I442 A443V436-K439 PolarHBondContact O-N 3.11Å; K439-I442 PolarHBondContact O-N 3.49Å; K439-A443 PolarHBondContact O-N 2.96Å; K439-A443 VanDerWaalsContact O-N 3.13Å
440D40.1Very low43.8Very low68 Ų6899.1 Ų99.136%0.36446%0.458SS..Hα-helixtrans-73-36.3-177.7-53.6-31.1000113.2F183 R438 I442 A443 V444F183-D440 WeakPolarHBondContact CD2-OD2 3.47Å; F183-D440 WeakPolarHBondContact CE2-OD2 3.45Å; R438-D440 VanDerWaalsContact C-N 3.27Å; R438-D440 PolarHBondContact O-N 3.15Å; D440-I442 PolarHBondContact O-N 2.76Å; D440-A443 PolarHBondContact O-N 3.2Å; D440-V444 WeakPolarHBondContact O-CG2 3.42Å; D440-V444 PolarHBondContact O-N 2.82Å
441K41.4Very low43.8Very low164 Ų164103.7 Ų103.771%0.71348%0.479SS*.Hα-helixtrans-64.8-25.9177.1-73.7-165.5176.1-173.70113
442I46.6Very low43.8Very low108 Ų108109.7 Ų109.755%0.55451%0.507SS*.Hα-helixtrans-81.5-39.9175.7-60172.4000109.9K439 D440 V444 K445 H446K439-I442 PolarHBondContact O-N 3.49Å; D440-I442 PolarHBondContact O-N 2.76Å; I442-V444 PolarHBondContact O-N 3.11Å; I442-K445 PolarHBondContact O-N 2.97Å; I442-H446 PolarHBondContact O-N 3.27Å
443A47.3Very low43.7Very low55 Ų55116.3 Ų116.346%0.45554%0.537SS..Hα-helixtrans-64.8-38.6178.100000112.9K439 D440 H446 K447K439-A443 PolarHBondContact O-N 2.96Å; K439-A443 VanDerWaalsContact O-N 3.13Å; D440-A443 PolarHBondContact O-N 3.2Å; A443-H446 PolarHBondContact O-N 3.38Å; A443-K447 PolarHBondContact O-N 3.16Å
444V50Low43.8Very low75 Ų75120.9 Ų120.946%0.45556%0.561SS.*Hα-helixtrans-68.4-35177.3175.80000111.7D440 I442 H446 K447 M448D440-V444 WeakPolarHBondContact O-CG2 3.42Å; D440-V444 PolarHBondContact O-N 2.82Å; I442-V444 PolarHBondContact O-N 3.11Å; V444-H446 PolarHBondContact O-N 3.44Å; V444-K447 PolarHBondContact O-N 3.19Å; V444-M448 PolarHBondContact O-N 2.89Å
445K49.2Very low44.2Very low173 Ų173125.4 Ų125.475%0.75258%0.58SS**Hα-helixtrans-69-14.8175.5-89-167.8174.5-169.30114.6I442I442-K445 PolarHBondContact O-N 2.97Å
446H49.5Very low44.3Very low162 Ų162130.1 Ų130.175%0.7561%0.606SS**THydrogen-bonded Turntrans-96.7-7.5174.9-87.6-59.8000113.6I442 A443 V444I442-H446 PolarHBondContact O-N 3.27Å; A443-H446 PolarHBondContact O-N 3.38Å; V444-H446 PolarHBondContact O-N 3.44Å
447K48.2Very low44.5Very low159 Ų159138.8 Ų138.869%0.69164%0.644SS**THydrogen-bonded Turntrans-107.2-8.1176.8-76.4-173.8-178.4177.80113.9E179 A443 V444E179-K447 IonicContact OE1-NZ 3.88Å; E179-K447 PolarHBondContact OE1-NZ 2.72Å; A443-K447 PolarHBondContact O-N 3.16Å; V444-K447 PolarHBondContact O-N 3.19Å
448M42Very low44.8Very low215 Ų215140.2 Ų140.2100%1.05966%0.66SS**  trans-99.80164.7-73.5-177.9162.700108.5V444V444-M448 PolarHBondContact O-N 2.89Å

Retrieved 448 of 448 residues in 1058.3 ms (Link to these results)