A0A077Z2Z3_TRITR Loading...

protein-tyrosine-phosphatase

AlphaFold DB , UniProt , Accession A0A077Z2Z3, Species TRITR (Trichuris trichiura, Whipworm), Gene n/a, Length 676 aa.

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Site Residue pLDDT pLDDT confidence pLDDT10 pLDDT10 confidence SASA SASA [Ų] SASA10 SASA10 [Ų] RSA RSA unformatted RSA10 RSA10 unformatted Surface Surface10 (not used) Disorder (not used) Disorder Sec. str. Secondary structure Isomer Phi (φ) Psi (ψ) Omega (ω) Chi 1 (χ1) Chi 2 (χ2) Chi 3 (χ3) Chi 4 (χ4) Chi 5 (χ5) Tau (τ) Contacts (colored by PAE) Contact details
1M27.9Very low51.8Low170 Ų17052.1 Ų52.184%0.83729%0.287SS*.  0-37.80-78.4-167.3-154.300112.4S3 L4 M5M1-S3 VanDerWaalsContact C-N 3.35Å; M1-S3 PolarHBondContact O-N 3.38Å; M1-L4 WeakPolarHBondContact O-CB 3.44Å; M1-L4 PolarHBondContact O-N 2.92Å; M1-M5 PolarHBondContact O-N 2.9Å
2A28.2Very low54.6Low54 Ų5449.2 Ų49.245%0.44627%0.269SS..Hα-helixtrans-52.1-42.7179.700000114.8L4 M5 N6A2-L4 PolarHBondContact O-N 3.22Å; A2-M5 PolarHBondContact O-N 3.24Å; A2-N6 PolarHBondContact O-N 2.86Å; A2-N6 VanDerWaalsContact O-N 3.09Å
3S36.8Very low56.5Low71 Ų7147.3 Ų47.350%0.49726%0.261SS..Hα-helixtrans-68.8-31.2177.675.70000114M1 M5M1-S3 VanDerWaalsContact C-N 3.35Å; M1-S3 PolarHBondContact O-N 3.38Å; S3-M5 VanDerWaalsContact C-N 3.28Å; S3-M5 PolarHBondContact O-N 2.9Å
4L39.2Very low57.9Low55 Ų5547.9 Ų47.929%0.28827%0.269SS..Hα-helixtrans-69.8-25.7174.9-80.7154.9000111.8M1 A2 N552 Q555M1-L4 WeakPolarHBondContact O-CB 3.44Å; M1-L4 PolarHBondContact O-N 2.92Å; A2-L4 PolarHBondContact O-N 3.22Å; L4-N552 HydrophobicContact CD1-CB 4.39Å; L4-N552 WeakPolarHBondContact CD2-O 3.33Å; L4-Q555 HydrophobicContact CD2-CB 4.02Å
5M41.4Very low59.5Low27 Ų2745.9 Ų45.913%0.13326%0.257CS..Hα-helixtrans-91.2-24.9178.7-69.4-157.5-179.600114.5M1 A2 S3 S7 Q83 T86M1-M5 PolarHBondContact O-N 2.9Å; A2-M5 PolarHBondContact O-N 3.24Å; S3-M5 VanDerWaalsContact C-N 3.28Å; S3-M5 PolarHBondContact O-N 2.9Å; M5-S7 CarbonylContact O-C 3.59Å; M5-S7 PolarHBondContact O-N 2.85Å; M5-S7 VanDerWaalsContact O-N 3.15Å; M5-Q83 HydrophobicContact SD-CB 3.91Å; M5-Q83 HydrophobicContact SD-CG 3.74Å; M5-T86 HydrophobicContact CE-CG2 3.24Å
6N42.2Very low61Low90 Ų9044.9 Ų44.948%0.48125%0.253SS..Hα-helixtrans-60.4-22.4170.5-85.4-7.9000112.6A2 R8 Y120A2-N6 PolarHBondContact O-N 2.86Å; A2-N6 VanDerWaalsContact O-N 3.09Å; N6-R8 PolarHBondContact O-N 3.28Å; N6-R8 VanDerWaalsContact O-N 3.15Å; N6-Y120 WeakPolarHBondContact O-CE1 3.37Å; N6-Y120 VanDerWaalsContact O-CZ 3.23Å
7S53.2Low62.4Low19 Ų1943.3 Ų43.313%0.13325%0.249CC..SBendtrans-71.8100.9166.3151.50000109.6M5 R9M5-S7 CarbonylContact O-C 3.59Å; M5-S7 PolarHBondContact O-N 2.85Å; M5-S7 VanDerWaalsContact O-N 3.15Å; S7-R9 PolarHBondContact O-N 3.11Å; S7-R9 WeakPolarHBondContact OG-CB 3.32Å; S7-R9 WeakPolarHBondContact OG-CD 3.17Å; S7-R9 WeakPolarHBondContact OG-CG 3.3Å
8R60.6Low63.7Low37 Ų3747.2 Ų47.214%0.1427%0.267CS..G310 helixtrans-65.820.3173.7-66.3-175.2178.9169.11.1114.2N6 W10 F11 A79 Y120 Q145N6-R8 PolarHBondContact O-N 3.28Å; N6-R8 VanDerWaalsContact O-N 3.15Å; R8-W10 HydrophobicContact CB-CZ2 4.31Å; R8-W10 HydrophobicContact CG-CZ2 4.2Å; R8-W10 PolarHBondContact O-N 2.73Å; R8-W10 VanDerWaalsContact O-N 3.11Å; R8-F11 WeakPolarHBondContact O-CB 3.45Å; R8-F11 PolarHBondContact O-N 2.78Å; R8-A79 HydrophobicContact CG-CB 4.1Å; R8-Y120 HydrophobicContact CG-CE2 4.29Å; R8-Q145 PolarHBondContact NH1-O 3.41Å
9R71Confident64.8Low25 Ų2549 Ų499%0.09427%0.273CS..G310 helixtrans-62.8-19.6-174.3-73.6177.5-178.3-96.90.9113.7S7 F11 N107 A108 D110 N237S7-R9 PolarHBondContact O-N 3.11Å; S7-R9 WeakPolarHBondContact OG-CB 3.32Å; S7-R9 WeakPolarHBondContact OG-CD 3.17Å; S7-R9 WeakPolarHBondContact OG-CG 3.3Å; R9-F11 PolarHBondContact O-N 3.48Å; R9-F11 VanDerWaalsContact O-N 3.15Å; R9-N107 HydrophobicContact CB-CB 3.81Å; R9-N107 VanDerWaalsContact CB-CG 3.47Å; R9-N107 CarbonylContact O-C 3.5Å; R9-N107 VanDerWaalsContact O-CA 3.24Å; R9-N107 WeakPolarHBondContact O-CA 3.4Å; R9-A108 PolarHBondContact O-N 3.38Å; R9-D110 IonicContact CZ-OD1 2.62Å; R9-D110 IonicContact NH1-OD1 3.86Å; R9-D110 PolarHBondContact NH1-OD1 3.48Å; R9-D110 IonicContact NH1-OD2 2.64Å; R9-D110 IonicContact NH2-OD1 2.99Å; R9-D110 PolarHBondContact NH2-OD1 3.03Å; R9-N237 PolarHBondContact NH1-ND2 2.78Å
10W83.4Confident66Low8 Ų846.6 Ų46.63%0.0326%0.259CS..G310 helixtrans-66.7-7.2171.244.9-99.8000113.4R8 H12 F33 L34 V35 L78 A79 V82 P105 N107R8-W10 HydrophobicContact CB-CZ2 4.31Å; R8-W10 HydrophobicContact CG-CZ2 4.2Å; R8-W10 PolarHBondContact O-N 2.73Å; R8-W10 VanDerWaalsContact O-N 3.11Å; W10-H12 PolarHBondContact O-CD2 3.34Å; W10-F33 HydrophobicContact CB-CE2 4.03Å; W10-F33 HydrophobicContact CG-CE2 4.15Å; W10-L34 WeakPolarHBondContact O-CA 3.36Å; W10-V35 HydrophobicContact CD2-CG2 4.44Å; W10-V35 HydrophobicContact CE3-CB 3.47Å; W10-V35 VanDerWaalsContact CE3-CB 3.47Å; W10-V35 HydrophobicContact CE3-CG1 4.5Å; W10-V35 HydrophobicContact CE3-CG2 3.35Å; W10-V35 HydrophobicContact CZ3-CB 3.45Å; W10-V35 VanDerWaalsContact CZ3-CB 3.45Å; W10-V35 HydrophobicContact CZ3-CG1 4.01Å; W10-V35 HydrophobicContact CZ3-CG2 3.41Å; W10-V35 VanDerWaalsContact CZ3-CG2 3.41Å; W10-V35 PolarHBondContact O-N 3.45Å; W10-L78 HydrophobicContact CH2-CB 3.8Å; W10-L78 HydrophobicContact CZ3-CB 4.43Å; W10-A79 HydrophobicContact CZ2-CB 4.2Å; W10-V82 HydrophobicContact CD2-CG1 4.14Å; W10-V82 HydrophobicContact CD2-CG2 4.17Å; W10-V82 HydrophobicContact CE3-CG2 4.02Å; W10-V82 HydrophobicContact CG-CG1 4.4Å; W10-V82 HydrophobicContact CH2-CB 4.33Å; W10-V82 HydrophobicContact CH2-CG2 3.76Å; W10-V82 HydrophobicContact CZ2-CB 4Å; W10-V82 HydrophobicContact CZ2-CG1 4.34Å; W10-V82 HydrophobicContact CZ2-CG2 3.91Å; W10-V82 HydrophobicContact CZ3-CG2 3.8Å; W10-P105 HydrophobicContact CB-CB 4.09Å; W10-N107 PolarHBondContact N-OD1 2.64Å
11F86.1Confident67.2Low17 Ų1748 Ų488%0.07526%0.264CS..BIsolated β-bridgetrans-84.3125.1175.9-174.7-101.3000111.8R8 R9 P13 V35 P37 F45 A108 P148 G149R8-F11 WeakPolarHBondContact O-CB 3.45Å; R8-F11 PolarHBondContact O-N 2.78Å; R9-F11 PolarHBondContact O-N 3.48Å; R9-F11 VanDerWaalsContact O-N 3.15Å; F11-P13 HydrophobicContact CE1-CB 3.95Å; F11-V35 CarbonylContact C-O 3.57Å; F11-V35 WeakPolarHBondContact CA-O 3.46Å; F11-V35 HydrophobicContact CD2-CB 4.19Å; F11-V35 HydrophobicContact CD2-CG1 3.98Å; F11-V35 HydrophobicContact CE2-CG1 4.32Å; F11-P37 HydrophobicContact CZ-CG 3.96Å; F11-F45 AromaticContact CE2-CD1 3.55Å; F11-F45 HydrophobicContact CE2-CD1 3.55Å; F11-F45 AromaticContact CE2-CE1 3.55Å; F11-F45 HydrophobicContact CE2-CE1 3.55Å; F11-F45 HydrophobicContact CZ-CD1 4.15Å; F11-F45 AromaticContact CZ-CE1 3.75Å; F11-F45 HydrophobicContact CZ-CE1 3.75Å; F11-A108 WeakPolarHBondContact O-CB 3.47Å; F11-P148 HydrophobicContact CD1-CB 4.46Å; F11-P148 HydrophobicContact CE1-CB 4.34Å; F11-P148 HydrophobicContact CZ-CB 4.44Å; F11-G149 VanDerWaalsContact CE1-CA 3.5Å
12H85Confident69.9Low17 Ų1744.7 Ų44.78%0.07925%0.247CC..  trans-114.1108.8177.4-71.1-107.8000110.4W10 C14 L15 V35 R36 P37 F106 A108W10-H12 PolarHBondContact O-CD2 3.34Å; H12-C14 VanDerWaalsContact C-N 3.29Å; H12-C14 PolarHBondContact O-N 3.02Å; H12-L15 HydrophobicContact CB-CB 4.1Å; H12-L15 HydrophobicContact CB-CD1 3.53Å; H12-L15 HydrophobicContact CB-CG 3.64Å; H12-L15 VanDerWaalsContact CG-CD1 3.41Å; H12-L15 VanDerWaalsContact ND1-CD1 3.29Å; H12-L15 WeakPolarHBondContact ND1-CD1 3.4Å; H12-V35 PolarHBondContact N-O 3.1Å; H12-R36 WeakPolarHBondContact O-CA 3.39Å; H12-R36 WeakPolarHBondContact O-CB 3.37Å; H12-P37 WeakPolarHBondContact O-CD 3.48Å; H12-F106 AromaticContact CE1-CD1 3.82Å; H12-F106 AromaticContact NE2-CD1 3.7Å; H12-F106 PolarHBondContact NE2-O 3.1Å; H12-A108 VanDerWaalsContact CE1-CA 3.45Å; H12-A108 WeakPolarHBondContact CE1-CA 3.5Å; H12-A108 PolarHBondContact NE2-N 3.14Å
13P79.2Confident72.6Confident25 Ų2544.3 Ų44.316%0.16224%0.237CC..SBendtrans-71.5-22.7-17326-33.1000113.4F11 F168F11-P13 HydrophobicContact CE1-CB 3.95Å; P13-F168 HydrophobicContact CB-CD1 3.75Å; P13-F168 HydrophobicContact CB-CE1 3.98Å; P13-F168 HydrophobicContact CG-CD1 4.26Å; P13-F168 HydrophobicContact CG-CE1 4.28Å
14C76.3Confident75.1Confident55 Ų5540.9 Ų40.937%0.37221%0.213SC..SBendtrans-102.5-23.4-171.4-50.60000114.5H12 T16 R39 F168H12-C14 VanDerWaalsContact C-N 3.29Å; H12-C14 PolarHBondContact O-N 3.02Å; C14-T16 PolarHBondContact O-N 2.86Å; C14-R39 PolarHBondContact O-NH2 3.36Å; C14-F168 HydrophobicContact CB-CE1 4.43Å; C14-F168 WeakPolarHBondContact SG-CE1 3.36Å; C14-F168 WeakPolarHBondContact SG-CZ 3.27Å
15L82.1Confident77.2Confident18 Ų1841.7 Ų41.79%0.09422%0.216CC..  trans-66130.7-161.2-70.7-176.9000111.7H12 Q19 A20 L23 L34 R36H12-L15 HydrophobicContact CB-CB 4.1Å; H12-L15 HydrophobicContact CB-CD1 3.53Å; H12-L15 HydrophobicContact CB-CG 3.64Å; H12-L15 VanDerWaalsContact CG-CD1 3.41Å; H12-L15 VanDerWaalsContact ND1-CD1 3.29Å; H12-L15 WeakPolarHBondContact ND1-CD1 3.4Å; L15-Q19 HydrophobicContact CD2-CB 3.86Å; L15-A20 HydrophobicContact CB-CB 4.39Å; L15-A20 HydrophobicContact CD1-CB 4.33Å; L15-L23 HydrophobicContact CD1-CD1 3.61Å; L15-L23 HydrophobicContact CD2-CD1 3.38Å; L15-L23 HydrophobicContact CG-CD1 4.15Å; L15-L34 HydrophobicContact CD1-CD1 4.06Å; L15-L34 HydrophobicContact CD1-CD2 3.66Å; L15-R36 HydrophobicContact CB-CB 4.39Å; L15-R36 WeakPolarHBondContact O-CD 3.33Å
16T83.1Confident79.1Confident31 Ų3147.3 Ų47.319%0.1924%0.242CC..  trans-76.6165.816360.70000110.1C14 I18 Q19 A20C14-T16 PolarHBondContact O-N 2.86Å; T16-I18 VanDerWaalsContact C-N 3.31Å; T16-I18 PolarHBondContact O-N 2.87Å; T16-Q19 PolarHBondContact O-N 3.37Å; T16-Q19 WeakPolarHBondContact OG1-CB 3.17Å; T16-Q19 VanDerWaalsContact OG1-CD 3.3Å; T16-Q19 WeakPolarHBondContact OG1-CG 3.04Å; T16-Q19 PolarHBondContact OG1-N 3.17Å; T16-Q19 VanDerWaalsContact OG1-N 3.16Å; T16-Q19 PolarHBondContact OG1-OE1 2.81Å; T16-A20 VanDerWaalsContact O-CB 3.32Å; T16-A20 WeakPolarHBondContact O-CB 3.19Å; T16-A20 PolarHBondContact O-N 3.48Å
17G85.6Confident80.8Confident17 Ų1750.4 Ų50.418%0.17525%0.247CC..Hα-helixtrans-53.8-49.6172.600000111.8Q19 A20 E21G17-Q19 PolarHBondContact O-N 2.94Å; G17-A20 WeakPolarHBondContact O-CB 3.48Å; G17-A20 PolarHBondContact O-N 2.93Å; G17-E21 WeakPolarHBondContact O-CG 3.46Å; G17-E21 PolarHBondContact O-N 3.03Å
18I85.3Confident82Confident113 Ų11349.6 Ų49.658%0.57924%0.242SC*.Hα-helixtrans-62.7-43.8-179.7-60169.1000112T16 E21 Q22T16-I18 VanDerWaalsContact C-N 3.31Å; T16-I18 PolarHBondContact O-N 2.87Å; I18-E21 WeakPolarHBondContact O-CB 3.37Å; I18-E21 PolarHBondContact O-N 3.41Å; I18-Q22 WeakPolarHBondContact O-CG 3.44Å; I18-Q22 PolarHBondContact O-N 3.05Å
19Q85Confident83Confident82 Ų8249 Ų4938%0.38324%0.24SC..Hα-helixtrans-67.4-38177.5-71.5165.5-38.300111.8L15 T16 G17 E21 Q22 L23L15-Q19 HydrophobicContact CD2-CB 3.86Å; T16-Q19 PolarHBondContact O-N 3.37Å; T16-Q19 WeakPolarHBondContact OG1-CB 3.17Å; T16-Q19 VanDerWaalsContact OG1-CD 3.3Å; T16-Q19 WeakPolarHBondContact OG1-CG 3.04Å; T16-Q19 PolarHBondContact OG1-N 3.17Å; T16-Q19 VanDerWaalsContact OG1-N 3.16Å; T16-Q19 PolarHBondContact OG1-OE1 2.81Å; G17-Q19 PolarHBondContact O-N 2.94Å; Q19-E21 VanDerWaalsContact C-N 3.31Å; Q19-Q22 PolarHBondContact O-N 3.28Å; Q19-L23 WeakPolarHBondContact O-CB 3.44Å; Q19-L23 VanDerWaalsContact O-CG 3.3Å; Q19-L23 WeakPolarHBondContact O-CG 3.21Å; Q19-L23 PolarHBondContact O-N 3.32Å
20A88Confident83.7Confident0 Ų049.9 Ų49.90%025%0.247CC..Hα-helixtrans-62.2-42.4173.500000110.9L15 T16 G17 L23 L24 L34L15-A20 HydrophobicContact CB-CB 4.39Å; L15-A20 HydrophobicContact CD1-CB 4.33Å; T16-A20 VanDerWaalsContact O-CB 3.32Å; T16-A20 WeakPolarHBondContact O-CB 3.19Å; T16-A20 PolarHBondContact O-N 3.48Å; G17-A20 WeakPolarHBondContact O-CB 3.48Å; G17-A20 PolarHBondContact O-N 2.93Å; A20-L23 PolarHBondContact O-N 3.4Å; A20-L24 VanDerWaalsContact O-CB 3.24Å; A20-L24 WeakPolarHBondContact O-CB 3.48Å; A20-L24 VanDerWaalsContact O-CG 3.25Å; A20-L24 WeakPolarHBondContact O-CG 3.31Å; A20-L24 PolarHBondContact O-N 3.45Å; A20-L34 HydrophobicContact CB-CD1 3.95Å; A20-L34 HydrophobicContact CB-CD2 4.28Å
21E90.7Very high83.9Confident78 Ų7849.5 Ų49.536%0.36425%0.245SC..Hα-helixtrans-60.3-50.4174.1-69.8175.8-177.200111.5G17 I18 Q19 L23 L24 M25 I55 H57G17-E21 WeakPolarHBondContact O-CG 3.46Å; G17-E21 PolarHBondContact O-N 3.03Å; I18-E21 WeakPolarHBondContact O-CB 3.37Å; I18-E21 PolarHBondContact O-N 3.41Å; Q19-E21 VanDerWaalsContact C-N 3.31Å; E21-L23 PolarHBondContact O-N 2.73Å; E21-L24 PolarHBondContact O-N 3.44Å; E21-M25 VanDerWaalsContact O-CB 3.24Å; E21-M25 WeakPolarHBondContact O-CB 3.48Å; E21-M25 WeakPolarHBondContact O-CG 3.44Å; E21-M25 PolarHBondContact O-N 2.82Å; E21-I55 HydrophobicContact CB-CG1 4.08Å; E21-I55 HydrophobicContact CG-CB 3.86Å; E21-I55 HydrophobicContact CG-CG1 3.92Å; E21-I55 HydrophobicContact CG-CG2 3.99Å; E21-H57 IonicContact OE1-CD2 3.02Å; E21-H57 IonicContact OE1-NE2 2.61Å; E21-H57 PolarHBondContact OE1-NE2 3.15Å; E21-H57 VanDerWaalsContact OE1-NE2 3.12Å
22Q85.6Confident84.1Confident100 Ų10048.9 Ų48.947%0.46724%0.243SC..Hα-helixtrans-58.2-46.8178-73.2173.6-6.900112I18 Q19 M25 Q26I18-Q22 WeakPolarHBondContact O-CG 3.44Å; I18-Q22 PolarHBondContact O-N 3.05Å; Q19-Q22 PolarHBondContact O-N 3.28Å; Q22-M25 PolarHBondContact O-N 2.82Å; Q22-Q26 WeakPolarHBondContact O-CB 3.35Å; Q22-Q26 WeakPolarHBondContact O-CG 3.45Å; Q22-Q26 PolarHBondContact O-N 2.99Å
23L85Confident84.5Confident45 Ų4548.1 Ų48.124%0.23624%0.239CC..Hα-helixtrans-65.5-45.5-180-75.8171.4000112.2L15 Q19 A20 E21 Q26 R27 G28 F106L15-L23 HydrophobicContact CD1-CD1 3.61Å; L15-L23 HydrophobicContact CD2-CD1 3.38Å; L15-L23 HydrophobicContact CG-CD1 4.15Å; Q19-L23 WeakPolarHBondContact O-CB 3.44Å; Q19-L23 VanDerWaalsContact O-CG 3.3Å; Q19-L23 WeakPolarHBondContact O-CG 3.21Å; Q19-L23 PolarHBondContact O-N 3.32Å; A20-L23 PolarHBondContact O-N 3.4Å; E21-L23 PolarHBondContact O-N 2.73Å; L23-Q26 PolarHBondContact O-N 2.92Å; L23-R27 WeakPolarHBondContact O-CB 3.46Å; L23-R27 PolarHBondContact O-N 3.28Å; L23-G28 PolarHBondContact O-N 2.83Å; L23-F106 HydrophobicContact CB-CE1 4.13Å; L23-F106 HydrophobicContact CB-CZ 4.14Å
24L88.2Confident85.1Confident0 Ų046.9 Ų46.90%023%0.232CC..Hα-helixtrans-66.7-37.7178.4-73.2172.5000111.4A20 E21 G28 L34 R50 I55 F106A20-L24 VanDerWaalsContact O-CB 3.24Å; A20-L24 WeakPolarHBondContact O-CB 3.48Å; A20-L24 VanDerWaalsContact O-CG 3.25Å; A20-L24 WeakPolarHBondContact O-CG 3.31Å; A20-L24 PolarHBondContact O-N 3.45Å; E21-L24 PolarHBondContact O-N 3.44Å; L24-G28 CarbonylContact O-C 3.57Å; L24-G28 WeakPolarHBondContact O-CA 3.21Å; L24-G28 PolarHBondContact O-N 2.78Å; L24-L34 HydrophobicContact CD1-CD2 4.17Å; L24-L34 HydrophobicContact CD1-CG 4.24Å; L24-L34 HydrophobicContact CD2-CD2 4.08Å; L24-L34 HydrophobicContact CG-CD2 3.91Å; L24-L34 HydrophobicContact CG-CG 4.46Å; L24-R50 HydrophobicContact CB-CB 4.27Å; L24-R50 WeakPolarHBondContact O-CD 3.07Å; L24-R50 PolarHBondContact O-NH1 2.85Å; L24-I55 HydrophobicContact CB-CD1 3.68Å; L24-I55 HydrophobicContact CD1-CD1 4.27Å; L24-I55 HydrophobicContact CD1-CG2 4.11Å; L24-F106 HydrophobicContact CD2-CB 3.96Å; L24-F106 HydrophobicContact CD2-CD2 4.15Å; L24-F106 HydrophobicContact CD2-CG 4.01Å
25M84.9Confident85.9Confident71 Ų7144.3 Ų44.335%0.3521%0.214SC..Hα-helixtrans-71.1-40.4175.5-71.8-57.4-162.900112.9E21 Q22 R50 S53 I55E21-M25 VanDerWaalsContact O-CB 3.24Å; E21-M25 WeakPolarHBondContact O-CB 3.48Å; E21-M25 WeakPolarHBondContact O-CG 3.44Å; E21-M25 PolarHBondContact O-N 2.82Å; Q22-M25 PolarHBondContact O-N 2.82Å; M25-R50 PolarHBondContact O-NH1 3.07Å; M25-S53 WeakPolarHBondContact CE-O 3.37Å; M25-I55 HydrophobicContact CE-CD1 3.88Å; M25-I55 HydrophobicContact CE-CG1 3.69Å; M25-I55 HydrophobicContact CG-CD1 4.08Å; M25-I55 HydrophobicContact CG-CG1 4.17Å; M25-I55 HydrophobicContact SD-CD1 3.88Å; M25-I55 HydrophobicContact SD-CG1 4.25Å
26Q80.2Confident86.4Confident145 Ų14544 Ų4468%0.67821%0.212SC*.Hα-helixtrans-78.5-36.1-177.4-72.3173.69.400113Q22 L23Q22-Q26 WeakPolarHBondContact O-CB 3.35Å; Q22-Q26 WeakPolarHBondContact O-CG 3.45Å; Q22-Q26 PolarHBondContact O-N 2.99Å; L23-Q26 PolarHBondContact O-N 2.92Å
27R78.7Confident86.6Confident156 Ų15644 Ų4459%0.58921%0.212SC*.Hα-helixtrans-132.2-16.3-168.5-56.5-179.581.7-177.75.9114.1L23 F29 F106L23-R27 WeakPolarHBondContact O-CB 3.46Å; L23-R27 PolarHBondContact O-N 3.28Å; R27-F29 WeakPolarHBondContact O-CE2 3.43Å; R27-F106 HydrophobicContact CB-CE2 3.8Å; R27-F106 HydrophobicContact CB-CZ 4.04Å
28G78.8Confident86.7Confident2 Ų243.8 Ų43.82%0.02121%0.208CC..  trans-79-179172.700000111.4L23 L24 R50L23-G28 PolarHBondContact O-N 2.83Å; L24-G28 CarbonylContact O-C 3.57Å; L24-G28 WeakPolarHBondContact O-CA 3.21Å; L24-G28 PolarHBondContact O-N 2.78Å; G28-R50 PolarHBondContact O-NH1 3.03Å
29F81.4Confident86.5Confident25 Ų2543.5 Ų43.511%0.1120%0.199CC..  trans-136.9171.3178.3-55.1-79.8000110.2R27 G31 S32 R50 Y104 Q600 K603 E607R27-F29 WeakPolarHBondContact O-CE2 3.43Å; F29-G31 PolarHBondContact O-N 3.4Å; F29-S32 PolarHBondContact N-OG 3.41Å; F29-S32 WeakPolarHBondContact O-CA 3.42Å; F29-S32 WeakPolarHBondContact O-CB 3.44Å; F29-S32 PolarHBondContact O-N 3.13Å; F29-S32 PolarHBondContact O-OG 3.3Å; F29-R50 WeakPolarHBondContact O-CB 3.21Å; F29-R50 WeakPolarHBondContact O-CG 3.38Å; F29-Y104 HydrophobicContact CB-CD2 4.31Å; F29-Q600 HydrophobicContact CZ-CB 4.39Å; F29-Q600 HydrophobicContact CZ-CG 4.26Å; F29-K603 HydrophobicContact CB-CB 4.25Å; F29-K603 HydrophobicContact CB-CD 4.12Å; F29-K603 HydrophobicContact CD1-CB 3.08Å; F29-K603 HydrophobicContact CD1-CD 3.79Å; F29-K603 HydrophobicContact CD1-CG 4.09Å; F29-K603 HydrophobicContact CD2-CB 4.08Å; F29-K603 HydrophobicContact CD2-CD 3.11Å; F29-K603 HydrophobicContact CD2-CG 4.25Å; F29-K603 HydrophobicContact CE1-CB 3.21Å; F29-K603 HydrophobicContact CE1-CD 3.9Å; F29-K603 HydrophobicContact CE1-CG 4.23Å; F29-K603 HydrophobicContact CE2-CB 4.19Å; F29-K603 HydrophobicContact CE2-CD 3.25Å; F29-K603 HydrophobicContact CE2-CG 4.39Å; F29-K603 HydrophobicContact CG-CB 3.51Å; F29-K603 HydrophobicContact CG-CD 3.35Å; F29-K603 HydrophobicContact CG-CG 4.06Å; F29-K603 HydrophobicContact CZ-CB 3.77Å; F29-K603 HydrophobicContact CZ-CD 3.64Å; F29-K603 HydrophobicContact CZ-CG 4.36Å; F29-E607 WeakPolarHBondContact CA-OE1 3.43Å
30D86.1Confident86.4Confident43 Ų4343.7 Ų43.723%0.2321%0.21CC..THydrogen-bonded Turntrans-55.3123.4172.7-170.944.6000111.6S32 R51 G52 Y104 E607D30-S32 VanDerWaalsContact C-N 3.33Å; D30-R51 VanDerWaalsContact OD1-CA 3.25Å; D30-R51 WeakPolarHBondContact OD1-CA 3.09Å; D30-G52 PolarHBondContact OD1-N 2.92Å; D30-Y104 WeakPolarHBondContact O-CD2 3.38Å; D30-Y104 WeakPolarHBondContact O-CE2 3.44Å; D30-E607 PolarHBondContact N-OE1 3.47Å
31G87.5Confident86.3Confident0 Ų045.9 Ų45.90%022%0.223CC..THydrogen-bonded Turntrans805-171.300000115.4F29 R50 P101 K103 Y104F29-G31 PolarHBondContact O-N 3.4Å; G31-R50 WeakPolarHBondContact CA-O 3.39Å; G31-R50 PolarHBondContact N-O 3.36Å; G31-P101 VanDerWaalsContact CA-O 3.25Å; G31-P101 WeakPolarHBondContact CA-O 3.43Å; G31-K103 PolarHBondContact O-N 3.07Å; G31-Y104 PolarHBondContact O-N 2.8Å
32S89.8Confident86Confident3 Ų351.5 Ų51.52%0.02125%0.249CC..EExtended strand (participates in β ladder)trans-68.6141167.4-75.60000111.5F29 D30 V49 R50 Y104F29-S32 PolarHBondContact N-OG 3.41Å; F29-S32 WeakPolarHBondContact O-CA 3.42Å; F29-S32 WeakPolarHBondContact O-CB 3.44Å; F29-S32 PolarHBondContact O-N 3.13Å; F29-S32 PolarHBondContact O-OG 3.3Å; D30-S32 VanDerWaalsContact C-N 3.33Å; S32-V49 CarbonylContact O-C 3.55Å; S32-V49 WeakPolarHBondContact O-CA 3.24Å; S32-R50 PolarHBondContact O-N 2.82Å; S32-Y104 CarbonylContact C-O 3.55Å; S32-Y104 WeakPolarHBondContact CA-O 3.49Å
33F93.1Very high85.9Confident1 Ų149.2 Ų49.20%0.00425%0.253CS..EExtended strand (participates in β ladder)trans-144.5154.6-175.771.7-93.2000113.5W10 L47 S48 V49 V82 L102 Y104 P105 F106W10-F33 HydrophobicContact CB-CE2 4.03Å; W10-F33 HydrophobicContact CG-CE2 4.15Å; F33-L47 HydrophobicContact CB-CD1 4.08Å; F33-L47 HydrophobicContact CD2-CD1 3.89Å; F33-L47 HydrophobicContact CG-CD1 4.37Å; F33-S48 CarbonylContact C-O 3.58Å; F33-S48 WeakPolarHBondContact CA-O 3.3Å; F33-V49 HydrophobicContact CB-CG1 4.4Å; F33-V49 HydrophobicContact CB-CG2 4.07Å; F33-V82 HydrophobicContact CE2-CG1 3.59Å; F33-V82 HydrophobicContact CZ-CG1 3.87Å; F33-L102 HydrophobicContact CB-CD1 3.38Å; F33-L102 HydrophobicContact CD1-CB 4.48Å; F33-L102 HydrophobicContact CD1-CD1 3.35Å; F33-L102 HydrophobicContact CD1-CG 3.59Å; F33-L102 HydrophobicContact CD2-CD1 3.55Å; F33-L102 HydrophobicContact CD2-CG 4.18Å; F33-L102 HydrophobicContact CE1-CD1 3.87Å; F33-L102 HydrophobicContact CE1-CD2 4.49Å; F33-L102 HydrophobicContact CE1-CG 3.59Å; F33-L102 HydrophobicContact CE2-CD1 4.06Å; F33-L102 HydrophobicContact CE2-CD2 4.44Å; F33-L102 HydrophobicContact CE2-CG 4.2Å; F33-L102 HydrophobicContact CG-CD1 3.13Å; F33-L102 HydrophobicContact CG-CG 3.87Å; F33-L102 HydrophobicContact CZ-CD1 4.18Å; F33-L102 HydrophobicContact CZ-CD2 4.32Å; F33-L102 HydrophobicContact CZ-CG 3.89Å; F33-Y104 WeakPolarHBondContact CD1-O 3.41Å; F33-Y104 PolarHBondContact N-O 2.76Å; F33-P105 HydrophobicContact CE1-CB 4.12Å; F33-P105 HydrophobicContact CE1-CG 3.76Å; F33-P105 VanDerWaalsContact CE1-N 3.31Å; F33-P105 HydrophobicContact CE2-CB 4.28Å; F33-P105 HydrophobicContact CZ-CB 3.81Å; F33-P105 HydrophobicContact CZ-CG 3.59Å; F33-F106 WeakPolarHBondContact O-CA 3.18Å; F33-F106 WeakPolarHBondContact O-CB 3.44Å; F33-F106 PolarHBondContact O-N 2.79Å
34L92.8Very high86.2Confident0 Ų047.6 Ų47.60%024%0.244CC..EExtended strand (participates in β ladder)trans-142.9155.2167.959.287.8000110W10 L15 A20 L24 R36 S48 F106W10-L34 WeakPolarHBondContact O-CA 3.36Å; L15-L34 HydrophobicContact CD1-CD1 4.06Å; L15-L34 HydrophobicContact CD1-CD2 3.66Å; A20-L34 HydrophobicContact CB-CD1 3.95Å; A20-L34 HydrophobicContact CB-CD2 4.28Å; L24-L34 HydrophobicContact CD1-CD2 4.17Å; L24-L34 HydrophobicContact CD1-CG 4.24Å; L24-L34 HydrophobicContact CD2-CD2 4.08Å; L24-L34 HydrophobicContact CG-CD2 3.91Å; L24-L34 HydrophobicContact CG-CG 4.46Å; L34-R36 HydrophobicContact CD1-CB 4.16Å; L34-R36 HydrophobicContact CD1-CG 4.05Å; L34-S48 PolarHBondContact N-O 3.3Å; L34-S48 PolarHBondContact O-N 3.22Å; L34-F106 HydrophobicContact CB-CB 4.26Å; L34-F106 HydrophobicContact CD2-CD1 3.86Å; L34-F106 HydrophobicContact CD2-CG 4.43Å
35V93.1Very high86.4Confident0 Ų048.7 Ų48.70%025%0.249CC..EExtended strand (participates in β ladder)trans-106.5143.4169-178.40000108.5W10 F11 H12 F45 T46 L47 I60 V82W10-V35 HydrophobicContact CD2-CG2 4.44Å; W10-V35 HydrophobicContact CE3-CB 3.47Å; W10-V35 VanDerWaalsContact CE3-CB 3.47Å; W10-V35 HydrophobicContact CE3-CG1 4.5Å; W10-V35 HydrophobicContact CE3-CG2 3.35Å; W10-V35 HydrophobicContact CZ3-CB 3.45Å; W10-V35 VanDerWaalsContact CZ3-CB 3.45Å; W10-V35 HydrophobicContact CZ3-CG1 4.01Å; W10-V35 HydrophobicContact CZ3-CG2 3.41Å; W10-V35 VanDerWaalsContact CZ3-CG2 3.41Å; W10-V35 PolarHBondContact O-N 3.45Å; F11-V35 CarbonylContact C-O 3.57Å; F11-V35 WeakPolarHBondContact CA-O 3.46Å; F11-V35 HydrophobicContact CD2-CB 4.19Å; F11-V35 HydrophobicContact CD2-CG1 3.98Å; F11-V35 HydrophobicContact CE2-CG1 4.32Å; H12-V35 PolarHBondContact N-O 3.1Å; V35-F45 HydrophobicContact CG1-CB 4.05Å; V35-T46 WeakPolarHBondContact CA-O 3.49Å; V35-L47 HydrophobicContact CG2-CB 4.46Å; V35-L47 HydrophobicContact CG2-CD1 3.83Å; V35-I60 HydrophobicContact CG1-CD1 3.95Å; V35-I60 HydrophobicContact CG2-CD1 4.38Å; V35-V82 HydrophobicContact CG2-CG2 3.8Å
36R91.4Very high86.9Confident13 Ų1345.7 Ų45.75%0.04924%0.235CC..EExtended strand (participates in β ladder)trans-145.3161.1179.154.4173.1179.875.8-1.9110.2H12 L15 L34 F45 T46 S48 H57H12-R36 WeakPolarHBondContact O-CA 3.39Å; H12-R36 WeakPolarHBondContact O-CB 3.37Å; L15-R36 HydrophobicContact CB-CB 4.39Å; L15-R36 WeakPolarHBondContact O-CD 3.33Å; L34-R36 HydrophobicContact CD1-CB 4.16Å; L34-R36 HydrophobicContact CD1-CG 4.05Å; R36-F45 CarbonylContact O-C 3.57Å; R36-F45 WeakPolarHBondContact O-CA 3.33Å; R36-T46 WeakPolarHBondContact CG-O 3.48Å; R36-T46 PolarHBondContact N-O 2.9Å; R36-T46 PolarHBondContact O-N 3.11Å; R36-S48 PolarHBondContact NE-OG 2.8Å; R36-S48 VanDerWaalsContact NE-OG 3.09Å; R36-H57 PolarHBondContact NH2-ND1 2.85Å
37P88Confident87.6Confident31 Ų3138.8 Ų38.820%0.20120%0.202CC..EExtended strand (participates in β ladder)trans-55.6143168-25.935.7000112.1F11 H12F11-P37 HydrophobicContact CZ-CG 3.96Å; H12-P37 WeakPolarHBondContact O-CD 3.48Å
38S87.7Confident88.4Confident11 Ų1131.3 Ų31.38%0.07717%0.174CC..  trans-71.8136.5172.5177.50000109.7S40 T41 D44S38-S40 PolarHBondContact OG-N 2.9Å; S38-S40 PolarHBondContact OG-OG 2.77Å; S38-T41 WeakPolarHBondContact CB-O 3.36Å; S38-T41 PolarHBondContact OG-N 2.98Å; S38-T41 PolarHBondContact OG-O 3.31Å; S38-D44 VanDerWaalsContact CB-O 3.22Å; S38-D44 WeakPolarHBondContact CB-O 3.41Å; S38-D44 PolarHBondContact N-O 3.01Å
39R81.3Confident89.2Confident108 Ų10831.2 Ų31.241%0.40817%0.173SC..SBendtrans-98.6-12.5176.9-60.6-59-171.6178.52.6112.6C14C14-R39 PolarHBondContact O-NH2 3.36Å
40S83Confident89.7Confident86 Ų8631.2 Ų31.260%0.60117%0.172SC*.SBendtrans-94.5-27.3176.562.70000112.7S38 K59S38-S40 PolarHBondContact OG-N 2.9Å; S38-S40 PolarHBondContact OG-OG 2.77Å; S40-K59 PolarHBondContact OG-NZ 2.85Å
41T84.9Confident89.9Confident46 Ų4630.2 Ų30.228%0.28217%0.166SC..SBendtrans-133.8116.8-175.8-45.60000107.1S38 D44S38-T41 WeakPolarHBondContact CB-O 3.36Å; S38-T41 PolarHBondContact OG-N 2.98Å; S38-T41 PolarHBondContact OG-O 3.31Å; T41-D44 HydrophobicContact CG2-CB 4.07Å; T41-D44 WeakPolarHBondContact CG2-OD2 3.45Å
42E84.4Confident89.6Confident195 Ų19532.1 Ų32.191%0.91119%0.185SC*.THydrogen-bonded Turntrans-67.8143.1179-172.2169.9-171.100110.7D44E42-D44 PolarHBondContact O-N 2.82Å; E42-D44 VanDerWaalsContact O-N 3.16Å
43G84.7Confident89.4Confident52 Ų5237.4 Ų37.454%0.53622%0.222SC..THydrogen-bonded Turntrans80.7-25.6-176.500000115.3F45 S62G43-F45 WeakPolarHBondContact O-CE2 3.46Å; G43-S62 WeakPolarHBondContact O-CB 3.27Å
44D90.8Very high89.3Confident11 Ų1143.3 Ų43.36%0.05924%0.244CC..  trans-78.8168.3177.3-87.36.3000113.1S38 T41 E42 I60 Q61 S62 Y70S38-D44 VanDerWaalsContact CB-O 3.22Å; S38-D44 WeakPolarHBondContact CB-O 3.41Å; S38-D44 PolarHBondContact N-O 3.01Å; T41-D44 HydrophobicContact CG2-CB 4.07Å; T41-D44 WeakPolarHBondContact CG2-OD2 3.45Å; E42-D44 PolarHBondContact O-N 2.82Å; E42-D44 VanDerWaalsContact O-N 3.16Å; D44-I60 WeakPolarHBondContact CB-O 3.47Å; D44-Q61 WeakPolarHBondContact OD1-CA 3.42Å; D44-S62 PolarHBondContact OD1-N 3.24Å; D44-Y70 PolarHBondContact OD2-OH 2.81Å
45F92.6Very high89.3Confident23 Ų2344.4 Ų44.410%0.10125%0.25CC..EExtended strand (participates in β ladder)trans-119.7168.4177.2-58.5-84.4000111.8F11 V35 R36 G43 I60 Y67 L78F11-F45 AromaticContact CE2-CD1 3.55Å; F11-F45 HydrophobicContact CE2-CD1 3.55Å; F11-F45 AromaticContact CE2-CE1 3.55Å; F11-F45 HydrophobicContact CE2-CE1 3.55Å; F11-F45 HydrophobicContact CZ-CD1 4.15Å; F11-F45 AromaticContact CZ-CE1 3.75Å; F11-F45 HydrophobicContact CZ-CE1 3.75Å; V35-F45 HydrophobicContact CG1-CB 4.05Å; R36-F45 CarbonylContact O-C 3.57Å; R36-F45 WeakPolarHBondContact O-CA 3.33Å; G43-F45 WeakPolarHBondContact O-CE2 3.46Å; F45-I60 HydrophobicContact CB-CB 3.97Å; F45-I60 HydrophobicContact CB-CD1 4.14Å; F45-I60 HydrophobicContact CB-CG2 4.37Å; F45-I60 PolarHBondContact N-O 3.34Å; F45-I60 PolarHBondContact O-N 2.88Å; F45-Y67 HydrophobicContact CD2-CD1 4.29Å; F45-Y67 HydrophobicContact CD2-CE1 4Å; F45-Y67 HydrophobicContact CE2-CD1 4.42Å; F45-Y67 AromaticContact CE2-CE1 3.69Å; F45-Y67 HydrophobicContact CE2-CE1 3.69Å; F45-L78 HydrophobicContact CB-CD2 4.33Å; F45-L78 HydrophobicContact CD1-CD1 3.96Å; F45-L78 HydrophobicContact CD2-CD1 3.84Å; F45-L78 HydrophobicContact CD2-CD2 3.92Å; F45-L78 HydrophobicContact CD2-CG 4.34Å; F45-L78 HydrophobicContact CE1-CD1 3.93Å; F45-L78 HydrophobicContact CE2-CD1 3.88Å; F45-L78 HydrophobicContact CG-CD1 3.88Å; F45-L78 HydrophobicContact CG-CD2 4.15Å; F45-L78 HydrophobicContact CZ-CD1 3.89Å
46T94.4Very high89.3Confident8 Ų845.4 Ų45.45%0.04926%0.256CS..EExtended strand (participates in β ladder)trans-137.6122.8175.2-540000109.8V35 R36 H57 I58V35-T46 WeakPolarHBondContact CA-O 3.49Å; R36-T46 WeakPolarHBondContact CG-O 3.48Å; R36-T46 PolarHBondContact N-O 2.9Å; R36-T46 PolarHBondContact O-N 3.11Å; T46-H57 HydrophobicContact CG2-CB 3.79Å; T46-I58 CarbonylContact C-O 3.49Å; T46-I58 VanDerWaalsContact CA-O 3.3Å; T46-I58 WeakPolarHBondContact CA-O 3.27Å
47L94.8Very high89.4Confident0 Ų047.9 Ų47.90%027%0.268CS..EExtended strand (participates in β ladder)trans-84.2115.7168173.361.5000108.9F33 V35 V49 H57 I58 I60 L92 L102F33-L47 HydrophobicContact CB-CD1 4.08Å; F33-L47 HydrophobicContact CD2-CD1 3.89Å; F33-L47 HydrophobicContact CG-CD1 4.37Å; V35-L47 HydrophobicContact CG2-CB 4.46Å; V35-L47 HydrophobicContact CG2-CD1 3.83Å; L47-V49 HydrophobicContact CD1-CG2 4.12Å; L47-V49 HydrophobicContact CD2-CG2 4.26Å; L47-V49 HydrophobicContact CG-CG2 3.78Å; L47-H57 CarbonylContact O-C 3.59Å; L47-H57 WeakPolarHBondContact O-CA 3.4Å; L47-I58 HydrophobicContact CB-CB 4.25Å; L47-I58 HydrophobicContact CD2-CD1 4.14Å; L47-I58 PolarHBondContact N-O 3.06Å; L47-I58 PolarHBondContact O-N 3.18Å; L47-I60 HydrophobicContact CB-CD1 3.88Å; L47-I60 HydrophobicContact CB-CG1 4.42Å; L47-L92 HydrophobicContact CD2-CD2 4.04Å; L47-L102 HydrophobicContact CD1-CD1 3.82Å; L47-L102 HydrophobicContact CD2-CD1 4.01Å; L47-L102 HydrophobicContact CG-CD1 4.37Å
48S95.9Very high89.7Confident0 Ų047.6 Ų47.60%026%0.264CS..EExtended strand (participates in β ladder)trans-105.3120.5178.7-53.50000108.8F33 L34 R36 T56 H57F33-S48 CarbonylContact C-O 3.58Å; F33-S48 WeakPolarHBondContact CA-O 3.3Å; L34-S48 PolarHBondContact N-O 3.3Å; L34-S48 PolarHBondContact O-N 3.22Å; R36-S48 PolarHBondContact NE-OG 2.8Å; R36-S48 VanDerWaalsContact NE-OG 3.09Å; S48-T56 CarbonylContact C-O 3.58Å; S48-T56 WeakPolarHBondContact CA-O 3.43Å; S48-H57 WeakPolarHBondContact CB-ND1 3.29Å; S48-H57 PolarHBondContact OG-CE1 2.99Å; S48-H57 PolarHBondContact OG-ND1 3.17Å
49V95.3Very high89.9Confident0 Ų052 Ų520%028%0.282CS..EExtended strand (participates in β ladder)trans-124.4128.1-173.6-169.90000109.7S32 F33 L47 R51 I55 T56 I58 I100 P101 L102S32-V49 CarbonylContact O-C 3.55Å; S32-V49 WeakPolarHBondContact O-CA 3.24Å; F33-V49 HydrophobicContact CB-CG1 4.4Å; F33-V49 HydrophobicContact CB-CG2 4.07Å; L47-V49 HydrophobicContact CD1-CG2 4.12Å; L47-V49 HydrophobicContact CD2-CG2 4.26Å; L47-V49 HydrophobicContact CG-CG2 3.78Å; V49-R51 HydrophobicContact CG1-CG 4.41Å; V49-I55 CarbonylContact O-C 3.58Å; V49-I55 WeakPolarHBondContact O-CA 3.3Å; V49-T56 PolarHBondContact N-O 3.3Å; V49-T56 PolarHBondContact O-N 3.33Å; V49-I58 HydrophobicContact CG2-CD1 4.45Å; V49-I100 HydrophobicContact CB-CG2 4.08Å; V49-I100 HydrophobicContact CG1-CG2 3.96Å; V49-I100 HydrophobicContact CG2-CG2 4.01Å; V49-P101 WeakPolarHBondContact CG1-O 3.43Å; V49-L102 HydrophobicContact CG2-CD1 4.11Å
50R92.1Very high90.5Very high24 Ų2446.8 Ų46.89%0.09126%0.262CS..EExtended strand (participates in β ladder)trans-77.8128.3170.7177.7164.4175.3-170.9-10.5110.3L24 M25 G28 F29 G31 S32 G52 I55 E607L24-R50 HydrophobicContact CB-CB 4.27Å; L24-R50 WeakPolarHBondContact O-CD 3.07Å; L24-R50 PolarHBondContact O-NH1 2.85Å; M25-R50 PolarHBondContact O-NH1 3.07Å; G28-R50 PolarHBondContact O-NH1 3.03Å; F29-R50 WeakPolarHBondContact O-CB 3.21Å; F29-R50 WeakPolarHBondContact O-CG 3.38Å; G31-R50 WeakPolarHBondContact CA-O 3.39Å; G31-R50 PolarHBondContact N-O 3.36Å; S32-R50 PolarHBondContact O-N 2.82Å; R50-G52 PolarHBondContact NE-O 3.43Å; R50-I55 HydrophobicContact CB-CD1 3.59Å; R50-I55 HydrophobicContact CG-CD1 3.85Å; R50-E607 IonicContact CZ-OE1 3.74Å; R50-E607 VanDerWaalsContact CZ-OE1 3.27Å; R50-E607 IonicContact CZ-OE2 3.22Å; R50-E607 IonicContact NE-OE1 3.26Å; R50-E607 IonicContact NH1-OE1 3.25Å; R50-E607 IonicContact NH2-OE1 2.72Å; R50-E607 PolarHBondContact NH2-OE1 3.03Å; R50-E607 IonicContact NH2-OE2 3.45Å; R50-E607 PolarHBondContact NH2-OE2 3.16Å
51R89.5Confident91Very high23 Ų2345.7 Ų45.79%0.08725%0.248CC..EExtended strand (participates in β ladder)trans-130.896.8177.5-69.4169.474.6-153.59.1108.4D30 V49 S53 R54 T56 E94D30-R51 VanDerWaalsContact OD1-CA 3.25Å; D30-R51 WeakPolarHBondContact OD1-CA 3.09Å; V49-R51 HydrophobicContact CG1-CG 4.41Å; R51-S53 PolarHBondContact O-N 3.31Å; R51-S53 VanDerWaalsContact O-N 3.14Å; R51-R54 CarbonylContact C-O 3.53Å; R51-R54 HydrophobicContact CB-CG 4.18Å; R51-R54 VanDerWaalsContact CZ-NH2 3.27Å; R51-R54 PolarHBondContact N-O 3.48Å; R51-R54 VanDerWaalsContact NH1-NH2 3.12Å; R51-R54 VanDerWaalsContact NH2-NH2 3.11Å; R51-R54 WeakPolarHBondContact O-CG 3.49Å; R51-R54 PolarHBondContact O-N 2.88Å; R51-R54 VanDerWaalsContact O-O 3.09Å; R51-T56 WeakPolarHBondContact CD-OG1 3.19Å; R51-T56 PolarHBondContact NH1-OG1 3.16Å; R51-E94 IonicContact CZ-OE1 2.71Å; R51-E94 IonicContact CZ-OE2 3.27Å; R51-E94 IonicContact NH1-OE1 2.85Å; R51-E94 PolarHBondContact NH1-OE1 3.21Å; R51-E94 IonicContact NH1-OE2 4Å; R51-E94 PolarHBondContact NH1-OE2 3.46Å; R51-E94 IonicContact NH2-OE1 3.17Å; R51-E94 IonicContact NH2-OE2 2.88Å; R51-E94 PolarHBondContact NH2-OE2 3.37Å
52G83.2Confident91.2Very high39 Ų3945.1 Ų45.140%0.40225%0.245SC..THydrogen-bonded Turntrans54.6-116-172.200000111.7D30 R50D30-G52 PolarHBondContact OD1-N 2.92Å; R50-G52 PolarHBondContact NE-O 3.43Å
53S85.6Confident91.4Very high114 Ų11438.8 Ų38.880%0.79722%0.22SC*.THydrogen-bonded Turntrans-94.69.8179.459.70000114.4M25 R51M25-S53 WeakPolarHBondContact CE-O 3.37Å; R51-S53 PolarHBondContact O-N 3.31Å; R51-S53 VanDerWaalsContact O-N 3.14Å
54R90Very high91.3Very high125 Ų12539.8 Ų39.847%0.47223%0.231SC..EExtended strand (participates in β ladder)trans-125.5158175.367178.1-173-159.25.6112R51 E94R51-R54 CarbonylContact C-O 3.53Å; R51-R54 HydrophobicContact CB-CG 4.18Å; R51-R54 VanDerWaalsContact CZ-NH2 3.27Å; R51-R54 PolarHBondContact N-O 3.48Å; R51-R54 VanDerWaalsContact NH1-NH2 3.12Å; R51-R54 VanDerWaalsContact NH2-NH2 3.11Å; R51-R54 WeakPolarHBondContact O-CG 3.49Å; R51-R54 PolarHBondContact O-N 2.88Å; R51-R54 VanDerWaalsContact O-O 3.09Å; R54-E94 IonicContact NH2-OE2 2.89Å; R54-E94 PolarHBondContact NH2-OE2 3.18Å
55I92.9Very high91.1Very high24 Ų2447.2 Ų47.212%0.12327%0.265CS..EExtended strand (participates in β ladder)trans-112.7129.6171.8-53.6-61.2000107.7E21 L24 M25 V49 R50E21-I55 HydrophobicContact CB-CG1 4.08Å; E21-I55 HydrophobicContact CG-CB 3.86Å; E21-I55 HydrophobicContact CG-CG1 3.92Å; E21-I55 HydrophobicContact CG-CG2 3.99Å; L24-I55 HydrophobicContact CB-CD1 3.68Å; L24-I55 HydrophobicContact CD1-CD1 4.27Å; L24-I55 HydrophobicContact CD1-CG2 4.11Å; M25-I55 HydrophobicContact CE-CD1 3.88Å; M25-I55 HydrophobicContact CE-CG1 3.69Å; M25-I55 HydrophobicContact CG-CD1 4.08Å; M25-I55 HydrophobicContact CG-CG1 4.17Å; M25-I55 HydrophobicContact SD-CD1 3.88Å; M25-I55 HydrophobicContact SD-CG1 4.25Å; V49-I55 CarbonylContact O-C 3.58Å; V49-I55 WeakPolarHBondContact O-CA 3.3Å; R50-I55 HydrophobicContact CB-CD1 3.59Å; R50-I55 HydrophobicContact CG-CD1 3.85Å
56T93.2Very high91Very high20 Ų2048.1 Ų48.112%0.12327%0.269CS..EExtended strand (participates in β ladder)trans-102.8131.9174.2-62.70000108.9S48 V49 R51 I58 I100S48-T56 CarbonylContact C-O 3.58Å; S48-T56 WeakPolarHBondContact CA-O 3.43Å; V49-T56 PolarHBondContact N-O 3.3Å; V49-T56 PolarHBondContact O-N 3.33Å; R51-T56 WeakPolarHBondContact CD-OG1 3.19Å; R51-T56 PolarHBondContact NH1-OG1 3.16Å; T56-I58 HydrophobicContact CG2-CG1 4.11Å; T56-I100 HydrophobicContact CG2-CD1 4.19Å
57H93.8Very high90.8Very high65 Ų6549.6 Ų49.630%0.30127%0.274SS..EExtended strand (participates in β ladder)trans-109.8121.1176.2-63.1-61.2000109.8E21 R36 T46 L47 S48E21-H57 IonicContact OE1-CD2 3.02Å; E21-H57 IonicContact OE1-NE2 2.61Å; E21-H57 PolarHBondContact OE1-NE2 3.15Å; E21-H57 VanDerWaalsContact OE1-NE2 3.12Å; R36-H57 PolarHBondContact NH2-ND1 2.85Å; T46-H57 HydrophobicContact CG2-CB 3.79Å; L47-H57 CarbonylContact O-C 3.59Å; L47-H57 WeakPolarHBondContact O-CA 3.4Å; S48-H57 WeakPolarHBondContact CB-ND1 3.29Å; S48-H57 PolarHBondContact OG-CE1 2.99Å; S48-H57 PolarHBondContact OG-ND1 3.17Å
58I93.5Very high90.7Very high26 Ų2650.1 Ų50.113%0.13328%0.277CS..EExtended strand (participates in β ladder)trans-113.1122.1-178.1-52169.1000107.3T46 L47 V49 T56 L69 L92 I100T46-I58 CarbonylContact C-O 3.49Å; T46-I58 VanDerWaalsContact CA-O 3.3Å; T46-I58 WeakPolarHBondContact CA-O 3.27Å; L47-I58 HydrophobicContact CB-CB 4.25Å; L47-I58 HydrophobicContact CD2-CD1 4.14Å; L47-I58 PolarHBondContact N-O 3.06Å; L47-I58 PolarHBondContact O-N 3.18Å; V49-I58 HydrophobicContact CG2-CD1 4.45Å; T56-I58 HydrophobicContact CG2-CG1 4.11Å; I58-L69 HydrophobicContact CG2-CD1 4.25Å; I58-L69 HydrophobicContact CG2-CD2 3.99Å; I58-L92 HydrophobicContact CD1-CD1 4.08Å; I58-L92 HydrophobicContact CD1-CD2 3.82Å; I58-L92 HydrophobicContact CD1-CG 4.13Å; I58-I100 HydrophobicContact CD1-CD1 3.59Å; I58-I100 HydrophobicContact CD1-CG2 4.06Å; I58-I100 HydrophobicContact CG1-CD1 4.27Å
59K92.9Very high90.4Very high102 Ų10251.5 Ų51.544%0.44328%0.284SS..EExtended strand (participates in β ladder)trans-73.3135.7177.7-66.1-173178.5-175.50109.6S40 Y70S40-K59 PolarHBondContact OG-NZ 2.85Å; K59-Y70 HydrophobicContact CB-CD2 4.25Å; K59-Y70 HydrophobicContact CB-CE2 3.91Å
60I93.6Very high89.6Confident0 Ų056.2 Ų56.20%030%0.303CS..EExtended strand (participates in β ladder)trans-111.8119.6171.6-63157.8000106.3V35 D44 F45 L47 Y67 D68 L69 L78 L81V35-I60 HydrophobicContact CG1-CD1 3.95Å; V35-I60 HydrophobicContact CG2-CD1 4.38Å; D44-I60 WeakPolarHBondContact CB-O 3.47Å; F45-I60 HydrophobicContact CB-CB 3.97Å; F45-I60 HydrophobicContact CB-CD1 4.14Å; F45-I60 HydrophobicContact CB-CG2 4.37Å; F45-I60 PolarHBondContact N-O 3.34Å; F45-I60 PolarHBondContact O-N 2.88Å; L47-I60 HydrophobicContact CB-CD1 3.88Å; L47-I60 HydrophobicContact CB-CG1 4.42Å; I60-Y67 HydrophobicContact CG2-CD1 4.34Å; I60-D68 CarbonylContact C-O 3.51Å; I60-D68 WeakPolarHBondContact CA-O 3.38Å; I60-L69 HydrophobicContact CB-CD2 4.29Å; I60-L69 HydrophobicContact CG1-CD2 3.48Å; I60-L69 VanDerWaalsContact CG1-CD2 3.48Å; I60-L78 HydrophobicContact CD1-CD2 4.33Å; I60-L78 HydrophobicContact CG2-CD2 3.75Å; I60-L81 HydrophobicContact CD1-CD2 4.38Å; I60-L81 HydrophobicContact CG1-CD2 4.5Å; I60-L81 HydrophobicContact CG2-CD1 3.85Å
61Q92.6Very high88.8Confident62 Ų6261.5 Ų61.529%0.2934%0.342SS..EExtended strand (participates in β ladder)trans-75.8139.2175.3-16417417.200109.6D44 T63 Y67 D68 Y70D44-Q61 WeakPolarHBondContact OD1-CA 3.42Å; Q61-T63 HydrophobicContact CG-CG2 4.35Å; Q61-Y67 WeakPolarHBondContact O-CA 3.42Å; Q61-D68 VanDerWaalsContact CB-OD1 3.27Å; Q61-D68 WeakPolarHBondContact CB-OD1 3.09Å; Q61-D68 PolarHBondContact N-O 2.92Å; Q61-D68 PolarHBondContact O-N 2.81Å; Q61-D68 PolarHBondContact OE1-OD1 3.5Å; Q61-Y70 HydrophobicContact CB-CD2 3.98Å; Q61-Y70 HydrophobicContact CB-CE1 4.19Å; Q61-Y70 HydrophobicContact CB-CE2 3.56Å; Q61-Y70 HydrophobicContact CB-CG 4.44Å; Q61-Y70 HydrophobicContact CG-CE1 4.04Å; Q61-Y70 HydrophobicContact CG-CE2 4.18Å
62S90.6Very high88.3Confident34 Ų3462 Ų6224%0.23835%0.354CS..EExtended strand (participates in β ladder)trans-118.6108.7168.8176.90000109.6G43 D44G43-S62 WeakPolarHBondContact O-CB 3.27Å; D44-S62 PolarHBondContact OD1-N 3.24Å
63T87.9Confident88.6Confident62 Ų6265.9 Ų65.938%0.3836%0.361SS..  trans-86.1-10.517962.90000113.3Q61 E65 F66Q61-T63 HydrophobicContact CG-CG2 4.35Å; T63-E65 VanDerWaalsContact C-N 3.27Å; T63-E65 PolarHBondContact OG1-N 3.14Å; T63-F66 HydrophobicContact CG2-CD2 4.36Å; T63-F66 HydrophobicContact CG2-CE1 4.08Å; T63-F66 HydrophobicContact CG2-CE2 3.77Å; T63-F66 HydrophobicContact CG2-CZ 3.61Å; T63-F66 PolarHBondContact N-O 2.85Å; T63-F66 VanDerWaalsContact N-O 3.16Å; T63-F66 WeakPolarHBondContact OG1-CD1 3.19Å; T63-F66 WeakPolarHBondContact OG1-CE1 3.39Å; T63-F66 PolarHBondContact OG1-N 2.77Å; T63-F66 VanDerWaalsContact OG1-N 3.12Å; T63-F66 PolarHBondContact OG1-O 3.21Å
64G83.4Confident88.9Confident73 Ų7366.7 Ų66.775%0.75335%0.351SS*.SBendtrans89.9-21.1-16900000113.6
65E85.8Confident89Confident167 Ų16761.8 Ų61.878%0.7833%0.333SS*.SBendtrans-103.8-35.1174.2-65.3-175.1167.100112.4T63T63-E65 VanDerWaalsContact C-N 3.27Å; T63-E65 PolarHBondContact OG1-N 3.14Å
66F89.5Confident88.7Confident43 Ų4364.1 Ų64.119%0.18936%0.355CS..  trans-152169.5-178.562.2-92.7000111.9T63 D68 K74 F75T63-F66 HydrophobicContact CG2-CD2 4.36Å; T63-F66 HydrophobicContact CG2-CE1 4.08Å; T63-F66 HydrophobicContact CG2-CE2 3.77Å; T63-F66 HydrophobicContact CG2-CZ 3.61Å; T63-F66 PolarHBondContact N-O 2.85Å; T63-F66 VanDerWaalsContact N-O 3.16Å; T63-F66 WeakPolarHBondContact OG1-CD1 3.19Å; T63-F66 WeakPolarHBondContact OG1-CE1 3.39Å; T63-F66 PolarHBondContact OG1-N 2.77Å; T63-F66 VanDerWaalsContact OG1-N 3.12Å; T63-F66 PolarHBondContact OG1-O 3.21Å; F66-D68 HydrophobicContact CD2-CB 4.45Å; F66-D68 HydrophobicContact CE2-CB 4.47Å; F66-K74 HydrophobicContact CB-CB 4.31Å; F66-K74 HydrophobicContact CD1-CD 4.26Å; F66-K74 HydrophobicContact CD2-CB 3.9Å; F66-K74 HydrophobicContact CD2-CD 3.8Å; F66-K74 HydrophobicContact CD2-CG 3.68Å; F66-K74 HydrophobicContact CE1-CD 4.17Å; F66-K74 HydrophobicContact CE2-CD 3.69Å; F66-K74 HydrophobicContact CE2-CG 3.82Å; F66-K74 HydrophobicContact CG-CB 4.18Å; F66-K74 HydrophobicContact CG-CD 4.09Å; F66-K74 HydrophobicContact CG-CG 4.28Å; F66-K74 HydrophobicContact CZ-CD 3.89Å; F66-F75 CarbonylContact C-O 3.52Å; F66-F75 VanDerWaalsContact CA-O 3.31Å; F66-F75 WeakPolarHBondContact CA-O 3.13Å; F66-F75 WeakPolarHBondContact CB-O 3.38Å
67Y90.5Very high88.3Confident39 Ų3964.1 Ų64.115%0.15336%0.356CS..EExtended strand (participates in β ladder)trans-117.9137.6174.6-57.8-90.1000110.2F45 I60 Q61 F75 L78F45-Y67 HydrophobicContact CD2-CD1 4.29Å; F45-Y67 HydrophobicContact CD2-CE1 4Å; F45-Y67 HydrophobicContact CE2-CD1 4.42Å; F45-Y67 AromaticContact CE2-CE1 3.69Å; F45-Y67 HydrophobicContact CE2-CE1 3.69Å; I60-Y67 HydrophobicContact CG2-CD1 4.34Å; Q61-Y67 WeakPolarHBondContact O-CA 3.42Å; Y67-F75 PolarHBondContact N-O 2.85Å; Y67-F75 PolarHBondContact O-N 3.26Å; Y67-L78 HydrophobicContact CD1-CD2 3.42Å; Y67-L78 VanDerWaalsContact CD1-CD2 3.42Å; Y67-L78 HydrophobicContact CD1-CG 3.72Å; Y67-L78 HydrophobicContact CE1-CD1 4.26Å; Y67-L78 HydrophobicContact CE1-CD2 3.83Å; Y67-L78 HydrophobicContact CE1-CG 3.66Å; Y67-L78 HydrophobicContact CG-CD2 3.93Å; Y67-L78 HydrophobicContact CG-CG 4.16Å
68D92.1Very high88Confident11 Ų1161.1 Ų61.16%0.05934%0.342CS..EExtended strand (participates in β ladder)trans-147.5176.2173.583.8-7.3000112I60 Q61 F66 Y70 C71 E73 K74I60-D68 CarbonylContact C-O 3.51Å; I60-D68 WeakPolarHBondContact CA-O 3.38Å; Q61-D68 VanDerWaalsContact CB-OD1 3.27Å; Q61-D68 WeakPolarHBondContact CB-OD1 3.09Å; Q61-D68 PolarHBondContact N-O 2.92Å; Q61-D68 PolarHBondContact O-N 2.81Å; Q61-D68 PolarHBondContact OE1-OD1 3.5Å; F66-D68 HydrophobicContact CD2-CB 4.45Å; F66-D68 HydrophobicContact CE2-CB 4.47Å; D68-Y70 PolarHBondContact OD1-N 2.79Å; D68-C71 PolarHBondContact OD2-N 3.5Å; D68-E73 WeakPolarHBondContact CB-O 3.44Å; D68-K74 HydrophobicContact CB-CG 4.48Å
69L90.8Very high87.5Confident29 Ų2960.4 Ų60.415%0.15234%0.341CS..SBendtrans-102.339.1174.4-59.1-174000112.3I58 I60 L81 Y85 L92I58-L69 HydrophobicContact CG2-CD1 4.25Å; I58-L69 HydrophobicContact CG2-CD2 3.99Å; I60-L69 HydrophobicContact CB-CD2 4.29Å; I60-L69 HydrophobicContact CG1-CD2 3.48Å; I60-L69 VanDerWaalsContact CG1-CD2 3.48Å; L69-L81 HydrophobicContact CD2-CD1 4.3Å; L69-L81 HydrophobicContact CD2-CD2 4.36Å; L69-Y85 HydrophobicContact CD1-CD2 4.09Å; L69-Y85 HydrophobicContact CD1-CE1 4.26Å; L69-Y85 HydrophobicContact CD1-CE2 3.43Å; L69-Y85 VanDerWaalsContact CD1-CE2 3.43Å; L69-Y85 HydrophobicContact CG-CE2 3.91Å; L69-L92 HydrophobicContact CD1-CD1 3.33Å
70Y78.9Confident87.2Confident99 Ų9959.9 Ų59.939%0.38834%0.34SS..SBendtrans54.982.2-176.3-70.2-94.9000112.1D44 K59 Q61 D68D44-Y70 PolarHBondContact OD2-OH 2.81Å; K59-Y70 HydrophobicContact CB-CD2 4.25Å; K59-Y70 HydrophobicContact CB-CE2 3.91Å; Q61-Y70 HydrophobicContact CB-CD2 3.98Å; Q61-Y70 HydrophobicContact CB-CE1 4.19Å; Q61-Y70 HydrophobicContact CB-CE2 3.56Å; Q61-Y70 HydrophobicContact CB-CG 4.44Å; Q61-Y70 HydrophobicContact CG-CE1 4.04Å; Q61-Y70 HydrophobicContact CG-CE2 4.18Å; D68-Y70 PolarHBondContact OD1-N 2.79Å
71C74.3Confident87.1Confident135 Ų13559.9 Ų59.991%0.91234%0.34SS*.SBendtrans89.124.9-175.5-50.60000116.1D68D68-C71 PolarHBondContact OD2-N 3.5Å
72G79Confident86.9Confident33 Ų3357 Ų5734%0.3433%0.327SS..SBendtrans-103.6-168.5173.800000113.6
73E89.2Confident86.7Confident120 Ų12057.8 Ų57.856%0.56133%0.326SS*.  trans-56145.5163.5-70.1-65.215400110.5D68 F75 F84D68-E73 WeakPolarHBondContact CB-O 3.44Å; E73-F75 HydrophobicContact CB-CE1 4.3Å; E73-F75 HydrophobicContact CB-CE2 3.65Å; E73-F75 HydrophobicContact CB-CZ 3.46Å; E73-F75 VanDerWaalsContact CB-CZ 3.46Å; E73-F75 HydrophobicContact CG-CZ 4.46Å; E73-F75 WeakPolarHBondContact O-CD2 3.2Å; E73-F75 WeakPolarHBondContact O-CE2 3.43Å; E73-F84 HydrophobicContact CG-CE1 4.3Å; E73-F84 HydrophobicContact CG-CZ 4.06Å
74K92.7Very high86.8Confident132 Ų13257.3 Ų57.357%0.57432%0.319SS*.  trans-102.4132.9179.9-63.3179.9-179.8-178.80109.7F66 D68F66-K74 HydrophobicContact CB-CB 4.31Å; F66-K74 HydrophobicContact CD1-CD 4.26Å; F66-K74 HydrophobicContact CD2-CB 3.9Å; F66-K74 HydrophobicContact CD2-CD 3.8Å; F66-K74 HydrophobicContact CD2-CG 3.68Å; F66-K74 HydrophobicContact CE1-CD 4.17Å; F66-K74 HydrophobicContact CE2-CD 3.69Å; F66-K74 HydrophobicContact CE2-CG 3.82Å; F66-K74 HydrophobicContact CG-CB 4.18Å; F66-K74 HydrophobicContact CG-CD 4.09Å; F66-K74 HydrophobicContact CG-CG 4.28Å; F66-K74 HydrophobicContact CZ-CD 3.89Å; D68-K74 HydrophobicContact CB-CG 4.48Å
75F90.9Very high87.2Confident21 Ų2154.5 Ų54.59%0.09229%0.286CS..BIsolated β-bridgetrans-121.3143.7-176.6-57-83000111F66 Y67 E73 S77 E80 L81 F84 Y85F66-F75 CarbonylContact C-O 3.52Å; F66-F75 VanDerWaalsContact CA-O 3.31Å; F66-F75 WeakPolarHBondContact CA-O 3.13Å; F66-F75 WeakPolarHBondContact CB-O 3.38Å; Y67-F75 PolarHBondContact N-O 2.85Å; Y67-F75 PolarHBondContact O-N 3.26Å; E73-F75 HydrophobicContact CB-CE1 4.3Å; E73-F75 HydrophobicContact CB-CE2 3.65Å; E73-F75 HydrophobicContact CB-CZ 3.46Å; E73-F75 VanDerWaalsContact CB-CZ 3.46Å; E73-F75 HydrophobicContact CG-CZ 4.46Å; E73-F75 WeakPolarHBondContact O-CD2 3.2Å; E73-F75 WeakPolarHBondContact O-CE2 3.43Å; F75-S77 VanDerWaalsContact C-N 3.29Å; F75-S77 PolarHBondContact O-N 2.93Å; F75-E80 HydrophobicContact CB-CB 4.17Å; F75-E80 HydrophobicContact CD1-CB 4.07Å; F75-L81 HydrophobicContact CB-CB 3.94Å; F75-L81 HydrophobicContact CD1-CB 4.45Å; F75-L81 HydrophobicContact CD2-CB 3.55Å; F75-L81 HydrophobicContact CD2-CD1 3.83Å; F75-L81 HydrophobicContact CD2-CG 3.63Å; F75-L81 HydrophobicContact CE2-CB 4.16Å; F75-L81 HydrophobicContact CE2-CD1 4.37Å; F75-L81 HydrophobicContact CE2-CG 3.93Å; F75-L81 HydrophobicContact CG-CB 3.7Å; F75-L81 HydrophobicContact CG-CG 4.32Å; F75-F84 HydrophobicContact CD1-CB 4.4Å; F75-F84 HydrophobicContact CE1-CB 3.41Å; F75-F84 VanDerWaalsContact CE1-CB 3.41Å; F75-F84 HydrophobicContact CE1-CD1 4.07Å; F75-F84 HydrophobicContact CE1-CD2 4.01Å; F75-F84 AromaticContact CE1-CG 3.57Å; F75-F84 HydrophobicContact CE1-CG 3.57Å; F75-F84 HydrophobicContact CZ-CB 3.66Å; F75-F84 AromaticContact CZ-CD1 3.49Å; F75-F84 HydrophobicContact CZ-CD1 3.49Å; F75-F84 VanDerWaalsContact CZ-CD1 3.49Å; F75-F84 HydrophobicContact CZ-CD2 4.2Å; F75-F84 HydrophobicContact CZ-CE1 4.16Å; F75-F84 AromaticContact CZ-CG 3.51Å; F75-F84 HydrophobicContact CZ-CG 3.51Å; F75-Y85 AromaticContact CE2-CE2 3.98Å; F75-Y85 HydrophobicContact CE2-CE2 3.98Å; F75-Y85 HydrophobicContact CZ-CE2 4.32Å
76A86.9Confident87.3Confident73 Ų7347.9 Ų47.960%0.60326%0.257SS*.SBendtrans-74.3-25.2178.900000111.6E80A76-E80 WeakPolarHBondContact CB-OE2 3.13Å; A76-E80 PolarHBondContact N-OE2 2.65Å
77S85.3Confident87.2Confident20 Ų2050.6 Ų50.614%0.1427%0.27CS..SBendtrans-139.1155.1175.376.10000113.4F75 A79 E80 L81F75-S77 VanDerWaalsContact C-N 3.29Å; F75-S77 PolarHBondContact O-N 2.93Å; S77-A79 PolarHBondContact O-N 2.96Å; S77-A79 VanDerWaalsContact O-N 3.14Å; S77-A79 PolarHBondContact OG-N 2.8Å; S77-E80 PolarHBondContact N-OE2 2.82Å; S77-E80 PolarHBondContact O-N 2.82Å; S77-E80 PolarHBondContact OG-N 2.82Å; S77-L81 PolarHBondContact O-N 2.84Å; S77-L81 VanDerWaalsContact O-N 3.17Å
78L86.6Confident87.2Confident2 Ų251.7 Ų51.71%0.0128%0.279CS..Hα-helixtrans-55.4-29.1171.4-71.5173.6000112.8W10 F45 I60 Y67 V82 P148W10-L78 HydrophobicContact CH2-CB 3.8Å; W10-L78 HydrophobicContact CZ3-CB 4.43Å; F45-L78 HydrophobicContact CB-CD2 4.33Å; F45-L78 HydrophobicContact CD1-CD1 3.96Å; F45-L78 HydrophobicContact CD2-CD1 3.84Å; F45-L78 HydrophobicContact CD2-CD2 3.92Å; F45-L78 HydrophobicContact CD2-CG 4.34Å; F45-L78 HydrophobicContact CE1-CD1 3.93Å; F45-L78 HydrophobicContact CE2-CD1 3.88Å; F45-L78 HydrophobicContact CG-CD1 3.88Å; F45-L78 HydrophobicContact CG-CD2 4.15Å; F45-L78 HydrophobicContact CZ-CD1 3.89Å; I60-L78 HydrophobicContact CD1-CD2 4.33Å; I60-L78 HydrophobicContact CG2-CD2 3.75Å; Y67-L78 HydrophobicContact CD1-CD2 3.42Å; Y67-L78 VanDerWaalsContact CD1-CD2 3.42Å; Y67-L78 HydrophobicContact CD1-CG 3.72Å; Y67-L78 HydrophobicContact CE1-CD1 4.26Å; Y67-L78 HydrophobicContact CE1-CD2 3.83Å; Y67-L78 HydrophobicContact CE1-CG 3.66Å; Y67-L78 HydrophobicContact CG-CD2 3.93Å; Y67-L78 HydrophobicContact CG-CG 4.16Å; L78-V82 WeakPolarHBondContact O-CG2 3.49Å; L78-V82 PolarHBondContact O-N 3.44Å; L78-P148 HydrophobicContact CD1-CB 4.45Å; L78-P148 HydrophobicContact CD1-CG 4.27Å
79A83.7Confident86.8Confident12 Ų1254.1 Ų54.110%0.09930%0.295CS..Hα-helixtrans-69-43.1179.300000112.4R8 W10 S77 L81 V82 Q83R8-A79 HydrophobicContact CG-CB 4.1Å; W10-A79 HydrophobicContact CZ2-CB 4.2Å; S77-A79 PolarHBondContact O-N 2.96Å; S77-A79 VanDerWaalsContact O-N 3.14Å; S77-A79 PolarHBondContact OG-N 2.8Å; A79-L81 VanDerWaalsContact C-N 3.35Å; A79-V82 PolarHBondContact O-N 2.85Å; A79-Q83 VanDerWaalsContact O-CB 3.26Å; A79-Q83 WeakPolarHBondContact O-CB 3.42Å; A79-Q83 PolarHBondContact O-N 2.85Å
80E86.5Confident86.7Confident90 Ų9057.7 Ų57.742%0.42131%0.314SS..Hα-helixtrans-64-41.4174.5-69.8167.7-176.300111.2F75 A76 S77 Q83 F84F75-E80 HydrophobicContact CB-CB 4.17Å; F75-E80 HydrophobicContact CD1-CB 4.07Å; A76-E80 WeakPolarHBondContact CB-OE2 3.13Å; A76-E80 PolarHBondContact N-OE2 2.65Å; S77-E80 PolarHBondContact N-OE2 2.82Å; S77-E80 PolarHBondContact O-N 2.82Å; S77-E80 PolarHBondContact OG-N 2.82Å; E80-Q83 PolarHBondContact O-N 3.13Å; E80-F84 WeakPolarHBondContact O-CB 3.35Å; E80-F84 PolarHBondContact O-N 2.83Å
81L91.2Very high87.2Confident0 Ų058.7 Ų58.70%032%0.323CS..Hα-helixtrans-57.7-51.7175.2-175.4156.1000111.2I60 L69 F75 S77 A79 F84 Y85I60-L81 HydrophobicContact CD1-CD2 4.38Å; I60-L81 HydrophobicContact CG1-CD2 4.5Å; I60-L81 HydrophobicContact CG2-CD1 3.85Å; L69-L81 HydrophobicContact CD2-CD1 4.3Å; L69-L81 HydrophobicContact CD2-CD2 4.36Å; F75-L81 HydrophobicContact CB-CB 3.94Å; F75-L81 HydrophobicContact CD1-CB 4.45Å; F75-L81 HydrophobicContact CD2-CB 3.55Å; F75-L81 HydrophobicContact CD2-CD1 3.83Å; F75-L81 HydrophobicContact CD2-CG 3.63Å; F75-L81 HydrophobicContact CE2-CB 4.16Å; F75-L81 HydrophobicContact CE2-CD1 4.37Å; F75-L81 HydrophobicContact CE2-CG 3.93Å; F75-L81 HydrophobicContact CG-CB 3.7Å; F75-L81 HydrophobicContact CG-CG 4.32Å; S77-L81 PolarHBondContact O-N 2.84Å; S77-L81 VanDerWaalsContact O-N 3.17Å; A79-L81 VanDerWaalsContact C-N 3.35Å; L81-F84 PolarHBondContact O-N 2.83Å; L81-Y85 HydrophobicContact CD2-CD2 3.92Å; L81-Y85 HydrophobicContact CD2-CE2 4.17Å; L81-Y85 HydrophobicContact CG-CD2 4.18Å; L81-Y85 HydrophobicContact CG-CE2 4.09Å; L81-Y85 VanDerWaalsContact O-CD2 3.24Å; L81-Y85 WeakPolarHBondContact O-CD2 3.15Å; L81-Y85 PolarHBondContact O-N 2.97Å
82V89.8Confident88Confident3 Ų352.7 Ų52.72%0.01828%0.281CS..Hα-helixtrans-64.5-41.8-179.8168.90000111.3W10 F33 V35 L78 A79 T86 L102W10-V82 HydrophobicContact CD2-CG1 4.14Å; W10-V82 HydrophobicContact CD2-CG2 4.17Å; W10-V82 HydrophobicContact CE3-CG2 4.02Å; W10-V82 HydrophobicContact CG-CG1 4.4Å; W10-V82 HydrophobicContact CH2-CB 4.33Å; W10-V82 HydrophobicContact CH2-CG2 3.76Å; W10-V82 HydrophobicContact CZ2-CB 4Å; W10-V82 HydrophobicContact CZ2-CG1 4.34Å; W10-V82 HydrophobicContact CZ2-CG2 3.91Å; W10-V82 HydrophobicContact CZ3-CG2 3.8Å; F33-V82 HydrophobicContact CE2-CG1 3.59Å; F33-V82 HydrophobicContact CZ-CG1 3.87Å; V35-V82 HydrophobicContact CG2-CG2 3.8Å; L78-V82 WeakPolarHBondContact O-CG2 3.49Å; L78-V82 PolarHBondContact O-N 3.44Å; A79-V82 PolarHBondContact O-N 2.85Å; V82-T86 WeakPolarHBondContact O-CB 3.33Å; V82-T86 PolarHBondContact O-N 2.98Å; V82-T86 PolarHBondContact O-OG1 2.89Å; V82-L102 HydrophobicContact CG1-CD2 4.42Å
83Q85.8Confident88.5Confident49 Ų4956.1 Ų56.123%0.22929%0.287CS..Hα-helixtrans-60.1-49.3177.2177.51742.100111M5 A79 E80 Y85 T86 E87M5-Q83 HydrophobicContact SD-CB 3.91Å; M5-Q83 HydrophobicContact SD-CG 3.74Å; A79-Q83 VanDerWaalsContact O-CB 3.26Å; A79-Q83 WeakPolarHBondContact O-CB 3.42Å; A79-Q83 PolarHBondContact O-N 2.85Å; E80-Q83 PolarHBondContact O-N 3.13Å; Q83-Y85 PolarHBondContact O-N 2.86Å; Q83-T86 PolarHBondContact O-N 2.82Å; Q83-T86 VanDerWaalsContact O-N 3.09Å; Q83-E87 HydrophobicContact CG-CG 4.32Å; Q83-E87 WeakPolarHBondContact CG-OE1 3.35Å; Q83-E87 PolarHBondContact NE2-OE1 3.3Å; Q83-E87 PolarHBondContact O-N 3.3Å
84F89.7Confident88.4Confident53 Ų5353.2 Ų53.223%0.23227%0.273CS..Hα-helixtrans-55.1-51-179.9177-93.4000112.1E73 F75 E80 L81 T86 E87 N88 Q91E73-F84 HydrophobicContact CG-CE1 4.3Å; E73-F84 HydrophobicContact CG-CZ 4.06Å; F75-F84 HydrophobicContact CD1-CB 4.4Å; F75-F84 HydrophobicContact CE1-CB 3.41Å; F75-F84 VanDerWaalsContact CE1-CB 3.41Å; F75-F84 HydrophobicContact CE1-CD1 4.07Å; F75-F84 HydrophobicContact CE1-CD2 4.01Å; F75-F84 AromaticContact CE1-CG 3.57Å; F75-F84 HydrophobicContact CE1-CG 3.57Å; F75-F84 HydrophobicContact CZ-CB 3.66Å; F75-F84 AromaticContact CZ-CD1 3.49Å; F75-F84 HydrophobicContact CZ-CD1 3.49Å; F75-F84 VanDerWaalsContact CZ-CD1 3.49Å; F75-F84 HydrophobicContact CZ-CD2 4.2Å; F75-F84 HydrophobicContact CZ-CE1 4.16Å; F75-F84 AromaticContact CZ-CG 3.51Å; F75-F84 HydrophobicContact CZ-CG 3.51Å; E80-F84 WeakPolarHBondContact O-CB 3.35Å; E80-F84 PolarHBondContact O-N 2.83Å; L81-F84 PolarHBondContact O-N 2.83Å; F84-T86 VanDerWaalsContact C-N 3.28Å; F84-T86 PolarHBondContact O-N 3.46Å; F84-E87 PolarHBondContact O-N 3.39Å; F84-N88 VanDerWaalsContact O-CB 3.3Å; F84-N88 WeakPolarHBondContact O-CB 3.18Å; F84-N88 PolarHBondContact O-N 3.12Å; F84-N88 PolarHBondContact O-ND2 2.87Å; F84-Q91 HydrophobicContact CE1-CB 4.15Å; F84-Q91 HydrophobicContact CE1-CG 4.24Å; F84-Q91 HydrophobicContact CZ-CG 4.29Å
85Y92.3Very high88Confident14 Ų1457.7 Ų57.76%0.05529%0.293CS..Hα-helixtrans-74.3-16.7-179.3-70.9-65.5000113.9L69 F75 L81 Q83 Q91 L92L69-Y85 HydrophobicContact CD1-CD2 4.09Å; L69-Y85 HydrophobicContact CD1-CE1 4.26Å; L69-Y85 HydrophobicContact CD1-CE2 3.43Å; L69-Y85 VanDerWaalsContact CD1-CE2 3.43Å; L69-Y85 HydrophobicContact CG-CE2 3.91Å; F75-Y85 AromaticContact CE2-CE2 3.98Å; F75-Y85 HydrophobicContact CE2-CE2 3.98Å; F75-Y85 HydrophobicContact CZ-CE2 4.32Å; L81-Y85 HydrophobicContact CD2-CD2 3.92Å; L81-Y85 HydrophobicContact CD2-CE2 4.17Å; L81-Y85 HydrophobicContact CG-CD2 4.18Å; L81-Y85 HydrophobicContact CG-CE2 4.09Å; L81-Y85 VanDerWaalsContact O-CD2 3.24Å; L81-Y85 WeakPolarHBondContact O-CD2 3.15Å; L81-Y85 PolarHBondContact O-N 2.97Å; Q83-Y85 PolarHBondContact O-N 2.86Å; Y85-Q91 HydrophobicContact CD1-CB 4.05Å; Y85-Q91 HydrophobicContact CE1-CB 4.03Å; Y85-L92 HydrophobicContact CD1-CB 3.77Å; Y85-L92 HydrophobicContact CD1-CD1 4.05Å; Y85-L92 HydrophobicContact CD1-CG 4.41Å; Y85-L92 HydrophobicContact CE1-CB 4.36Å; Y85-L92 HydrophobicContact CE1-CD1 4.12Å; Y85-L92 HydrophobicContact CG-CB 4.37Å; Y85-L92 HydrophobicContact CG-CD1 4.35Å
86T87.6Confident87.8Confident28 Ų2861.8 Ų61.817%0.17232%0.316CS..Hα-helixtrans-80.5-40.4172.3-540000111.3M5 V82 Q83 F84 L102M5-T86 HydrophobicContact CE-CG2 3.24Å; V82-T86 WeakPolarHBondContact O-CB 3.33Å; V82-T86 PolarHBondContact O-N 2.98Å; V82-T86 PolarHBondContact O-OG1 2.89Å; Q83-T86 PolarHBondContact O-N 2.82Å; Q83-T86 VanDerWaalsContact O-N 3.09Å; F84-T86 VanDerWaalsContact C-N 3.28Å; F84-T86 PolarHBondContact O-N 3.46Å; T86-L102 WeakPolarHBondContact CG2-O 3.22Å; T86-L102 WeakPolarHBondContact OG1-CD2 3.21Å
87E87.5Confident87.8Confident100 Ų10060.3 Ų60.347%0.46731%0.307SS..Hα-helixtrans-78.4-22.5179.1-69.2177.3177.100112.5Q83 F84 P89Q83-E87 HydrophobicContact CG-CG 4.32Å; Q83-E87 WeakPolarHBondContact CG-OE1 3.35Å; Q83-E87 PolarHBondContact NE2-OE1 3.3Å; Q83-E87 PolarHBondContact O-N 3.3Å; F84-E87 PolarHBondContact O-N 3.39Å; E87-P89 VanDerWaalsContact C-CD 3.48Å; E87-P89 VanDerWaalsContact O-CD 3.28Å; E87-P89 WeakPolarHBondContact O-CD 3.34Å
88N89.7Confident88Confident62 Ų6262.9 Ų62.933%0.33232%0.32SS..  trans-118.871.5179.1-57.9-85.8000110.7F84 D90 Q91F84-N88 VanDerWaalsContact O-CB 3.3Å; F84-N88 WeakPolarHBondContact O-CB 3.18Å; F84-N88 PolarHBondContact O-N 3.12Å; F84-N88 PolarHBondContact O-ND2 2.87Å; N88-D90 PolarHBondContact O-N 2.86Å; N88-Q91 HydrophobicContact CB-CB 4.2Å; N88-Q91 HydrophobicContact CB-CG 3.67Å; N88-Q91 WeakPolarHBondContact O-CB 3.48Å; N88-Q91 PolarHBondContact O-N 3.48Å
89P85.3Confident88.1Confident61 Ų6165.6 Ų65.640%0.39634%0.336SS..THydrogen-bonded Turntrans-60.8-22.7-171.824.3-34.9000113.8E87 Q91 V99E87-P89 VanDerWaalsContact C-CD 3.48Å; E87-P89 VanDerWaalsContact O-CD 3.28Å; E87-P89 WeakPolarHBondContact O-CD 3.34Å; P89-Q91 VanDerWaalsContact C-N 3.33Å; P89-V99 WeakPolarHBondContact O-CG1 3.44Å
90D87.2Confident88.5Confident105 Ų10565.3 Ų65.356%0.56133%0.333SS*.THydrogen-bonded Turntrans-82.2-6.2179-62.3-46.2000114.1N88 K93N88-D90 PolarHBondContact O-N 2.86Å; D90-K93 WeakPolarHBondContact O-CD 3.3Å; D90-K93 WeakPolarHBondContact O-CE 3.35Å; D90-K93 PolarHBondContact O-NZ 2.9Å
91Q90.6Very high88.5Confident120 Ų12062 Ų6256%0.56132%0.319SS*.THydrogen-bonded Turntrans-87.5-25.7-176.8-68.9-68.1-15.800113.2F84 Y85 N88 P89 K93F84-Q91 HydrophobicContact CE1-CB 4.15Å; F84-Q91 HydrophobicContact CE1-CG 4.24Å; F84-Q91 HydrophobicContact CZ-CG 4.29Å; Y85-Q91 HydrophobicContact CD1-CB 4.05Å; Y85-Q91 HydrophobicContact CE1-CB 4.03Å; N88-Q91 HydrophobicContact CB-CB 4.2Å; N88-Q91 HydrophobicContact CB-CG 3.67Å; N88-Q91 WeakPolarHBondContact O-CB 3.48Å; N88-Q91 PolarHBondContact O-N 3.48Å; P89-Q91 VanDerWaalsContact C-N 3.33Å; Q91-K93 PolarHBondContact O-N 3.22Å
92L91Very high88.5Confident8 Ų862.1 Ų62.14%0.04232%0.32CS..  trans-93.3101.7179.4-165.363.8000110.2L47 I58 L69 Y85 I100L47-L92 HydrophobicContact CD2-CD2 4.04Å; I58-L92 HydrophobicContact CD1-CD1 4.08Å; I58-L92 HydrophobicContact CD1-CD2 3.82Å; I58-L92 HydrophobicContact CD1-CG 4.13Å; L69-L92 HydrophobicContact CD1-CD1 3.33Å; Y85-L92 HydrophobicContact CD1-CB 3.77Å; Y85-L92 HydrophobicContact CD1-CD1 4.05Å; Y85-L92 HydrophobicContact CD1-CG 4.41Å; Y85-L92 HydrophobicContact CE1-CB 4.36Å; Y85-L92 HydrophobicContact CE1-CD1 4.12Å; Y85-L92 HydrophobicContact CG-CB 4.37Å; Y85-L92 HydrophobicContact CG-CD1 4.35Å; L92-I100 HydrophobicContact CB-CB 4.4Å; L92-I100 HydrophobicContact CD2-CB 3.98Å; L92-I100 HydrophobicContact CD2-CG2 3.81Å; L92-I100 HydrophobicContact CG-CB 3.9Å; L92-I100 HydrophobicContact CG-CD1 4.37Å; L92-I100 HydrophobicContact CG-CG2 4.27Å; L92-I100 PolarHBondContact O-N 2.69Å
93K89.9Confident88.2Confident106 Ų10667.5 Ų67.546%0.46134%0.343SS..BIsolated β-bridgetrans-132.5150.2-174.2-72.6168.6171.5149.90112.4D90 Q91 D98 V99D90-K93 WeakPolarHBondContact O-CD 3.3Å; D90-K93 WeakPolarHBondContact O-CE 3.35Å; D90-K93 PolarHBondContact O-NZ 2.9Å; Q91-K93 PolarHBondContact O-N 3.22Å; K93-D98 CarbonylContact C-O 3.6Å; K93-D98 VanDerWaalsContact CA-O 3.32Å; K93-D98 WeakPolarHBondContact CA-O 3.29Å; K93-V99 HydrophobicContact CD-CG2 4.44Å; K93-V99 HydrophobicContact CG-CG2 3.99Å
94E87Confident88.1Confident59 Ų5968.5 Ų68.528%0.27635%0.345SS..  trans-75.1166.8165.7-73-177.1147.500111.3R51 R54 N96 G97 D98 I100R51-E94 IonicContact CZ-OE1 2.71Å; R51-E94 IonicContact CZ-OE2 3.27Å; R51-E94 IonicContact NH1-OE1 2.85Å; R51-E94 PolarHBondContact NH1-OE1 3.21Å; R51-E94 IonicContact NH1-OE2 4Å; R51-E94 PolarHBondContact NH1-OE2 3.46Å; R51-E94 IonicContact NH2-OE1 3.17Å; R51-E94 IonicContact NH2-OE2 2.88Å; R51-E94 PolarHBondContact NH2-OE2 3.37Å; R54-E94 IonicContact NH2-OE2 2.89Å; R54-E94 PolarHBondContact NH2-OE2 3.18Å; E94-N96 WeakPolarHBondContact CB-OD1 3.45Å; E94-N96 PolarHBondContact O-N 3.43Å; E94-N96 VanDerWaalsContact O-N 3.09Å; E94-G97 PolarHBondContact O-N 2.75Å; E94-D98 HydrophobicContact CB-CB 4.41Å; E94-D98 PolarHBondContact N-O 2.88Å; E94-I100 HydrophobicContact CG-CD1 3.92Å; E94-I100 HydrophobicContact CG-CG1 4.2Å
95K84.1Confident87.8Confident225 Ų22568.1 Ų68.198%0.97835%0.348SS*.THydrogen-bonded Turntrans-57.9-24.6179.4-68.8-173.1177.8-175.90114G97K95-G97 VanDerWaalsContact C-N 3.3Å
96N86.8Confident87.5Confident107 Ų10769 Ų6957%0.57235%0.352SS*.THydrogen-bonded Turntrans-85.4-0.1177.365.6-10.4000113.3E94 D98E94-N96 WeakPolarHBondContact CB-OD1 3.45Å; E94-N96 PolarHBondContact O-N 3.43Å; E94-N96 VanDerWaalsContact O-N 3.09Å; N96-D98 VanDerWaalsContact ND2-CG 3.32Å; N96-D98 PolarHBondContact ND2-OD2 3.29Å; N96-D98 WeakPolarHBondContact OD1-CB 3.32Å; N96-D98 PolarHBondContact OD1-N 3.47Å
97G86.8Confident87Confident42 Ų4268.9 Ų68.943%0.43335%0.351SS..SBendtrans91.1-4.7-17800000114.9E94 K95 V99E94-G97 PolarHBondContact O-N 2.75Å; K95-G97 VanDerWaalsContact C-N 3.3Å; G97-V99 PolarHBondContact O-N 2.62Å
98D88.8Confident86.3Confident75 Ų7565.1 Ų65.140%0.40134%0.337SS..  trans-64.6122179.4-73.3-21.2000110.7K93 E94 N96K93-D98 CarbonylContact C-O 3.6Å; K93-D98 VanDerWaalsContact CA-O 3.32Å; K93-D98 WeakPolarHBondContact CA-O 3.29Å; E94-D98 HydrophobicContact CB-CB 4.41Å; E94-D98 PolarHBondContact N-O 2.88Å; N96-D98 VanDerWaalsContact ND2-CG 3.32Å; N96-D98 PolarHBondContact ND2-OD2 3.29Å; N96-D98 WeakPolarHBondContact OD1-CB 3.32Å; N96-D98 PolarHBondContact OD1-N 3.47Å
99V89.7Confident85.5Confident58 Ų5867.6 Ų67.635%0.35235%0.354SS..BIsolated β-bridgetrans-67.4136.4176.9178.30000110.4P89 K93 G97 P101P89-V99 WeakPolarHBondContact O-CG1 3.44Å; K93-V99 HydrophobicContact CD-CG2 4.44Å; K93-V99 HydrophobicContact CG-CG2 3.99Å; G97-V99 PolarHBondContact O-N 2.62Å; V99-P101 WeakPolarHBondContact O-CD 3.45Å
100I91Very high85.3Confident6 Ų666.2 Ų66.23%0.03134%0.343CS..  trans-101.3101172.7-57.9-179.3000107.3V49 T56 I58 L92 E94 L102V49-I100 HydrophobicContact CB-CG2 4.08Å; V49-I100 HydrophobicContact CG1-CG2 3.96Å; V49-I100 HydrophobicContact CG2-CG2 4.01Å; T56-I100 HydrophobicContact CG2-CD1 4.19Å; I58-I100 HydrophobicContact CD1-CD1 3.59Å; I58-I100 HydrophobicContact CD1-CG2 4.06Å; I58-I100 HydrophobicContact CG1-CD1 4.27Å; L92-I100 HydrophobicContact CB-CB 4.4Å; L92-I100 HydrophobicContact CD2-CB 3.98Å; L92-I100 HydrophobicContact CD2-CG2 3.81Å; L92-I100 HydrophobicContact CG-CB 3.9Å; L92-I100 HydrophobicContact CG-CD1 4.37Å; L92-I100 HydrophobicContact CG-CG2 4.27Å; L92-I100 PolarHBondContact O-N 2.69Å; E94-I100 HydrophobicContact CG-CD1 3.92Å; E94-I100 HydrophobicContact CG-CG1 4.2Å; I100-L102 PolarHBondContact O-N 3.44Å
101P87.6Confident85.1Confident20 Ų2063.1 Ų63.113%0.1333%0.329CS..  trans-70.4118.8-176.927.6-33.5000110.9G31 V49 V99 K103G31-P101 VanDerWaalsContact CA-O 3.25Å; G31-P101 WeakPolarHBondContact CA-O 3.43Å; V49-P101 WeakPolarHBondContact CG1-O 3.43Å; V99-P101 WeakPolarHBondContact O-CD 3.45Å; P101-K103 HydrophobicContact CB-CD 4.02Å; P101-K103 HydrophobicContact CB-CG 4.03Å
102L89.3Confident84.8Confident4 Ų458.3 Ų58.32%0.02131%0.308CS..  trans-99.683.3172.1-16169.8000109.1F33 L47 V49 V82 T86 I100F33-L102 HydrophobicContact CB-CD1 3.38Å; F33-L102 HydrophobicContact CD1-CB 4.48Å; F33-L102 HydrophobicContact CD1-CD1 3.35Å; F33-L102 HydrophobicContact CD1-CG 3.59Å; F33-L102 HydrophobicContact CD2-CD1 3.55Å; F33-L102 HydrophobicContact CD2-CG 4.18Å; F33-L102 HydrophobicContact CE1-CD1 3.87Å; F33-L102 HydrophobicContact CE1-CD2 4.49Å; F33-L102 HydrophobicContact CE1-CG 3.59Å; F33-L102 HydrophobicContact CE2-CD1 4.06Å; F33-L102 HydrophobicContact CE2-CD2 4.44Å; F33-L102 HydrophobicContact CE2-CG 4.2Å; F33-L102 HydrophobicContact CG-CD1 3.13Å; F33-L102 HydrophobicContact CG-CG 3.87Å; F33-L102 HydrophobicContact CZ-CD1 4.18Å; F33-L102 HydrophobicContact CZ-CD2 4.32Å; F33-L102 HydrophobicContact CZ-CG 3.89Å; L47-L102 HydrophobicContact CD1-CD1 3.82Å; L47-L102 HydrophobicContact CD2-CD1 4.01Å; L47-L102 HydrophobicContact CG-CD1 4.37Å; V49-L102 HydrophobicContact CG2-CD1 4.11Å; V82-L102 HydrophobicContact CG1-CD2 4.42Å; T86-L102 WeakPolarHBondContact CG2-O 3.22Å; T86-L102 WeakPolarHBondContact OG1-CD2 3.21Å; I100-L102 PolarHBondContact O-N 3.44Å
103K83.9Confident84.5Confident116 Ų11661.2 Ų61.250%0.50433%0.326SS..  trans-109.1-48.1-166.7-70.4178.5178.3178.10114.4G31 P101G31-K103 PolarHBondContact O-N 3.07Å; P101-K103 HydrophobicContact CB-CD 4.02Å; P101-K103 HydrophobicContact CB-CG 4.03Å
104Y83.4Confident84.6Confident69 Ų6958.4 Ų58.427%0.27132%0.315SS..EExtended strand (participates in β ladder)trans-119.5101.7-171-50-67.4000110.7F29 D30 G31 S32 F33 F106F29-Y104 HydrophobicContact CB-CD2 4.31Å; D30-Y104 WeakPolarHBondContact O-CD2 3.38Å; D30-Y104 WeakPolarHBondContact O-CE2 3.44Å; G31-Y104 PolarHBondContact O-N 2.8Å; S32-Y104 CarbonylContact C-O 3.55Å; S32-Y104 WeakPolarHBondContact CA-O 3.49Å; F33-Y104 WeakPolarHBondContact CD1-O 3.41Å; F33-Y104 PolarHBondContact N-O 2.76Å; Y104-F106 PolarHBondContact O-N 2.91Å; Y104-F106 VanDerWaalsContact O-N 3.13Å
105P84.9Confident84.9Confident46 Ų4656.3 Ų56.330%0.29930%0.304SS..EExtended strand (participates in β ladder)trans-55.6120.9172-18.927.5000110.2W10 F33 N107W10-P105 HydrophobicContact CB-CB 4.09Å; F33-P105 HydrophobicContact CE1-CB 4.12Å; F33-P105 HydrophobicContact CE1-CG 3.76Å; F33-P105 VanDerWaalsContact CE1-N 3.31Å; F33-P105 HydrophobicContact CE2-CB 4.28Å; F33-P105 HydrophobicContact CZ-CB 3.81Å; F33-P105 HydrophobicContact CZ-CG 3.59Å; P105-N107 PolarHBondContact O-N 2.95Å
106F84.6Confident85.4Confident32 Ų3246.1 Ų46.114%0.1426%0.259CS..  trans-90.992.6174.4-169.4-85.9000107.4H12 L23 L24 R27 F33 L34 Y104H12-F106 AromaticContact CE1-CD1 3.82Å; H12-F106 AromaticContact NE2-CD1 3.7Å; H12-F106 PolarHBondContact NE2-O 3.1Å; L23-F106 HydrophobicContact CB-CE1 4.13Å; L23-F106 HydrophobicContact CB-CZ 4.14Å; L24-F106 HydrophobicContact CD2-CB 3.96Å; L24-F106 HydrophobicContact CD2-CD2 4.15Å; L24-F106 HydrophobicContact CD2-CG 4.01Å; R27-F106 HydrophobicContact CB-CE2 3.8Å; R27-F106 HydrophobicContact CB-CZ 4.04Å; F33-F106 WeakPolarHBondContact O-CA 3.18Å; F33-F106 WeakPolarHBondContact O-CB 3.44Å; F33-F106 PolarHBondContact O-N 2.79Å; L34-F106 HydrophobicContact CB-CB 4.26Å; L34-F106 HydrophobicContact CD2-CD1 3.86Å; L34-F106 HydrophobicContact CD2-CG 4.43Å; Y104-F106 PolarHBondContact O-N 2.91Å; Y104-F106 VanDerWaalsContact O-N 3.13Å
107N76.8Confident85.6Confident26 Ų2641.5 Ų41.514%0.13923%0.234CC..PPolyproline II helixtrans-75.5141.3-170.7-75-3.7000112.9R9 W10 P105 Q555R9-N107 HydrophobicContact CB-CB 3.81Å; R9-N107 VanDerWaalsContact CB-CG 3.47Å; R9-N107 CarbonylContact O-C 3.5Å; R9-N107 VanDerWaalsContact O-CA 3.24Å; R9-N107 WeakPolarHBondContact O-CA 3.4Å; W10-N107 PolarHBondContact N-OD1 2.64Å; P105-N107 PolarHBondContact O-N 2.95Å; N107-Q555 PolarHBondContact ND2-OE1 3.45Å
108A74.1Confident85.9Confident21 Ų2140.5 Ų40.517%0.17422%0.219CC..PPolyproline II helixtrans-66.8138.1167.600000109.6R9 F11 H12R9-A108 PolarHBondContact O-N 3.38Å; F11-A108 WeakPolarHBondContact O-CB 3.47Å; H12-A108 VanDerWaalsContact CE1-CA 3.45Å; H12-A108 WeakPolarHBondContact CE1-CA 3.5Å; H12-A108 PolarHBondContact NE2-N 3.14Å
109T71.7Confident85.7Confident113 Ų11337.1 Ų37.169%0.69320%0.201SC*.PPolyproline II helixtrans-67.4147.6169.349.70000109.5
110D81.1Confident85.4Confident32 Ų3237.6 Ų37.617%0.17120%0.197CC..PPolyproline II helixtrans-54.3139.9172.7-61.4-42.1000109.6R9 T112 F117 S240R9-D110 IonicContact CZ-OD1 2.62Å; R9-D110 IonicContact NH1-OD1 3.86Å; R9-D110 PolarHBondContact NH1-OD1 3.48Å; R9-D110 IonicContact NH1-OD2 2.64Å; R9-D110 IonicContact NH2-OD1 2.99Å; R9-D110 PolarHBondContact NH2-OD1 3.03Å; D110-T112 PolarHBondContact O-N 3.06Å; D110-F117 HydrophobicContact CB-CD1 4.44Å; D110-F117 HydrophobicContact CB-CE1 4.07Å; D110-S240 PolarHBondContact OD2-OG 2.96Å
111P83.2Confident85.2Confident40 Ų4037.8 Ų37.826%0.2620%0.198SC..SBendtrans-67-16.5-177.830.2-39.5000112.9F117 Y151 L205P111-F117 HydrophobicContact CG-CE1 4.12Å; P111-F117 HydrophobicContact CG-CE2 4.09Å; P111-F117 HydrophobicContact CG-CZ 3.81Å; P111-Y151 HydrophobicContact CG-CE1 3.69Å; P111-Y151 WeakPolarHBondContact CG-OH 3.42Å; P111-L205 HydrophobicContact CB-CD1 3.93Å; P111-L205 HydrophobicContact CG-CD1 3.58Å
112T85.5Confident85.2Confident20 Ų2037.9 Ų37.912%0.12320%0.199CC..  trans-155.5152.8179.8-173.40000110.4D110 E114 W116 F117 S206D110-T112 PolarHBondContact O-N 3.06Å; T112-E114 VanDerWaalsContact C-N 3.33Å; T112-E114 HydrophobicContact CG2-CB 4.08Å; T112-E114 WeakPolarHBondContact OG1-CB 3.47Å; T112-E114 VanDerWaalsContact OG1-CG 3.27Å; T112-E114 WeakPolarHBondContact OG1-CG 3.43Å; T112-E114 PolarHBondContact OG1-N 3.36Å; T112-W116 HydrophobicContact CG2-CH2 3.95Å; T112-W116 HydrophobicContact CG2-CZ3 4.24Å; T112-F117 HydrophobicContact CG2-CB 3.68Å; T112-F117 HydrophobicContact CG2-CD1 4.35Å; T112-F117 HydrophobicContact CG2-CG 3.94Å; T112-S206 PolarHBondContact OG1-OG 3.14Å
113T85.3Confident85.2Confident69 Ų6938.5 Ų38.542%0.42321%0.207SC..  trans-91.50.7172.153.60000112.4
114E91.3Very high85.6Confident46 Ų4642.5 Ų42.522%0.21522%0.219CC..  trans-63.8137.8-178.5-72.1-59.8138.600112.6T112 W116 F117 S206 K247T112-E114 VanDerWaalsContact C-N 3.33Å; T112-E114 HydrophobicContact CG2-CB 4.08Å; T112-E114 WeakPolarHBondContact OG1-CB 3.47Å; T112-E114 VanDerWaalsContact OG1-CG 3.27Å; T112-E114 WeakPolarHBondContact OG1-CG 3.43Å; T112-E114 PolarHBondContact OG1-N 3.36Å; E114-W116 VanDerWaalsContact C-N 3.29Å; E114-W116 HydrophobicContact CB-CD2 4.04Å; E114-W116 HydrophobicContact CB-CG 4.4Å; E114-W116 HydrophobicContact CB-CH2 4.3Å; E114-W116 HydrophobicContact CB-CZ2 3.56Å; E114-W116 HydrophobicContact CG-CZ2 3.72Å; E114-W116 PolarHBondContact O-N 3.49Å; E114-F117 WeakPolarHBondContact O-CB 3.4Å; E114-F117 PolarHBondContact O-N 2.98Å; E114-F117 VanDerWaalsContact O-N 3.09Å; E114-S206 WeakPolarHBondContact CG-OG 3.36Å; E114-K247 VanDerWaalsContact OE1-CE 3.29Å; E114-K247 WeakPolarHBondContact OE1-CE 3.14Å; E114-K247 IonicContact OE1-NZ 3.89Å; E114-K247 PolarHBondContact OE1-NZ 3.18Å; E114-K247 WeakPolarHBondContact OE2-CE 3.26Å; E114-K247 IonicContact OE2-NZ 3.34Å
115R92.4Very high86Confident16 Ų1643 Ų436%0.0622%0.224CC..THydrogen-bonded Turntrans-72.3-19.4-171.3-68.1172.168.3-143.7-2.7113.8F117 N232 T233 K247 E260 E261R115-F117 PolarHBondContact O-N 3.28Å; R115-N232 HydrophobicContact CB-CB 3.85Å; R115-N232 WeakPolarHBondContact CB-OD1 3.43Å; R115-N232 PolarHBondContact NH1-ND2 3.09Å; R115-N232 CarbonylContact O-C 3.51Å; R115-N232 WeakPolarHBondContact O-CA 3.44Å; R115-T233 PolarHBondContact O-N 3.45Å; R115-K247 HydrophobicContact CG-CG 4.41Å; R115-E260 IonicContact CZ-OE1 3.51Å; R115-E260 IonicContact CZ-OE2 3.03Å; R115-E260 IonicContact NH1-OE1 3.12Å; R115-E260 PolarHBondContact NH1-OE1 3.45Å; R115-E260 IonicContact NH1-OE2 3.89Å; R115-E260 PolarHBondContact NH1-OE2 3.23Å; R115-E260 IonicContact NH2-OE1 3.58Å; R115-E260 PolarHBondContact NH2-OE1 3.3Å; R115-E260 IonicContact NH2-OE2 2.85Å; R115-E261 IonicContact CZ-OE1 2.73Å; R115-E261 IonicContact NE-OE1 2.69Å; R115-E261 PolarHBondContact NE-OE1 3.16Å; R115-E261 IonicContact NH2-OE1 3.06Å; R115-E261 PolarHBondContact NH2-OE1 3.35Å
116W94.2Very high86.4Confident10 Ų1040.9 Ų40.94%0.03821%0.209CC..THydrogen-bonded Turntrans-74.9-5.6172.350.6-102.6000113.3T112 E114 H118 F139 L140 V141 L205 V209 P230T112-W116 HydrophobicContact CG2-CH2 3.95Å; T112-W116 HydrophobicContact CG2-CZ3 4.24Å; E114-W116 VanDerWaalsContact C-N 3.29Å; E114-W116 HydrophobicContact CB-CD2 4.04Å; E114-W116 HydrophobicContact CB-CG 4.4Å; E114-W116 HydrophobicContact CB-CH2 4.3Å; E114-W116 HydrophobicContact CB-CZ2 3.56Å; E114-W116 HydrophobicContact CG-CZ2 3.72Å; E114-W116 PolarHBondContact O-N 3.49Å; W116-H118 PolarHBondContact O-CD2 3.16Å; W116-F139 HydrophobicContact CB-CE2 4.11Å; W116-F139 HydrophobicContact CD2-CE2 4.47Å; W116-F139 HydrophobicContact CG-CE2 4.1Å; W116-L140 WeakPolarHBondContact O-CA 3.47Å; W116-V141 HydrophobicContact CE3-CB 3.55Å; W116-V141 HydrophobicContact CE3-CG2 3.39Å; W116-V141 HydrophobicContact CH2-CG2 4.49Å; W116-V141 HydrophobicContact CZ3-CB 3.5Å; W116-V141 HydrophobicContact CZ3-CG1 4.1Å; W116-V141 HydrophobicContact CZ3-CG2 3.37Å; W116-V141 PolarHBondContact O-N 2.95Å; W116-L205 HydrophobicContact CH2-CB 3.7Å; W116-L205 HydrophobicContact CZ3-CB 4.27Å; W116-V209 HydrophobicContact CD2-CG2 4.47Å; W116-V209 HydrophobicContact CE3-CG2 4.27Å; W116-V209 HydrophobicContact CH2-CB 4.44Å; W116-V209 HydrophobicContact CH2-CG2 3.77Å; W116-V209 HydrophobicContact CZ2-CB 4.16Å; W116-V209 HydrophobicContact CZ2-CG1 4.48Å; W116-V209 HydrophobicContact CZ2-CG2 3.94Å; W116-V209 HydrophobicContact CZ3-CG2 3.95Å; W116-P230 HydrophobicContact CB-CB 3.77Å; W116-P230 HydrophobicContact CG-CB 4.31Å
117F93Very high86.9Confident10 Ų1042.9 Ų42.94%0.04422%0.219CC..BIsolated β-bridgetrans-88.7113.3172.8-177.5-111.3000110.5D110 P111 T112 E114 R115 V141 E143 Y151 T233D110-F117 HydrophobicContact CB-CD1 4.44Å; D110-F117 HydrophobicContact CB-CE1 4.07Å; P111-F117 HydrophobicContact CG-CE1 4.12Å; P111-F117 HydrophobicContact CG-CE2 4.09Å; P111-F117 HydrophobicContact CG-CZ 3.81Å; T112-F117 HydrophobicContact CG2-CB 3.68Å; T112-F117 HydrophobicContact CG2-CD1 4.35Å; T112-F117 HydrophobicContact CG2-CG 3.94Å; E114-F117 WeakPolarHBondContact O-CB 3.4Å; E114-F117 PolarHBondContact O-N 2.98Å; E114-F117 VanDerWaalsContact O-N 3.09Å; R115-F117 PolarHBondContact O-N 3.28Å; F117-V141 CarbonylContact C-O 3.48Å; F117-V141 WeakPolarHBondContact CA-O 3.01Å; F117-V141 HydrophobicContact CD2-CB 4.22Å; F117-V141 HydrophobicContact CD2-CG1 4Å; F117-V141 HydrophobicContact CE2-CG1 4.42Å; F117-E143 HydrophobicContact CZ-CG 4.1Å; F117-Y151 AromaticContact CE2-CD1 3.8Å; F117-Y151 HydrophobicContact CE2-CD1 3.8Å; F117-Y151 AromaticContact CE2-CE1 3.85Å; F117-Y151 HydrophobicContact CE2-CE1 3.85Å; F117-Y151 HydrophobicContact CZ-CD1 4.4Å; F117-Y151 HydrophobicContact CZ-CE1 4.03Å; F117-T233 VanDerWaalsContact O-CG2 3.23Å; F117-T233 WeakPolarHBondContact O-CG2 3.4Å
118H91.3Very high87.7Confident22 Ų2246.5 Ų46.510%0.10224%0.235CC..  trans-92.6-0.1-176.7-75.7-124.3000113.5W116 I121 L140 V141 L231W116-H118 PolarHBondContact O-CD2 3.16Å; H118-I121 HydrophobicContact CB-CD1 3.55Å; H118-I121 HydrophobicContact CB-CG1 3.91Å; H118-I121 HydrophobicContact CB-CG2 4.48Å; H118-L140 HydrophobicContact CB-CD1 4.5Å; H118-V141 PolarHBondContact N-O 2.79Å; H118-L231 PolarHBondContact NE2-O 2.81Å
119G86.1Confident88.6Confident4 Ų447.6 Ų47.64%0.04124%0.238CC..  trans63.8-134.9-177.300000112.1I121 R142 E143G119-I121 PolarHBondContact O-N 3.38Å; G119-R142 CarbonylContact O-C 3.49Å; G119-R142 WeakPolarHBondContact O-CA 3.24Å; G119-R142 WeakPolarHBondContact O-CB 3.03Å; G119-E143 PolarHBondContact O-N 3.47Å
120Y81.8Confident89.7Confident67 Ų6742.2 Ų42.226%0.26321%0.205SC..SBendtrans-83.488.8-176.7-166.9-98.8000111.8N6 R8 E143 Q145N6-Y120 WeakPolarHBondContact O-CE1 3.37Å; N6-Y120 VanDerWaalsContact O-CZ 3.23Å; R8-Y120 HydrophobicContact CG-CE2 4.29Å; Y120-E143 HydrophobicContact CD2-CB 4.37Å; Y120-Q145 HydrophobicContact CE2-CG 3.9Å
121I86.8Confident90.3Very high11 Ų1144 Ų446%0.05621%0.214CC..  trans-128.6149.5167.862.1166000110.2H118 G119 E125 A126 L129 L140 R142H118-I121 HydrophobicContact CB-CD1 3.55Å; H118-I121 HydrophobicContact CB-CG1 3.91Å; H118-I121 HydrophobicContact CB-CG2 4.48Å; G119-I121 PolarHBondContact O-N 3.38Å; I121-E125 HydrophobicContact CB-CB 4.43Å; I121-A126 HydrophobicContact CD1-CB 3.83Å; I121-L129 HydrophobicContact CD1-CD1 4.09Å; I121-L140 HydrophobicContact CD1-CD1 3.93Å; I121-L140 HydrophobicContact CD1-CD2 4.21Å; I121-R142 HydrophobicContact CD1-CB 4.34Å; I121-R142 HydrophobicContact CG1-CB 3.64Å; I121-R142 HydrophobicContact CG1-CG 4.36Å; I121-R142 WeakPolarHBondContact O-CD 3.11Å; I121-R142 PolarHBondContact O-NH1 3.02Å
122S88.5Confident90.6Very high21 Ų2148.1 Ų48.115%0.14723%0.23CC..  trans-73164.5178.367.30000112.6R124 E125 A126 Q145S122-R124 VanDerWaalsContact C-N 3.31Å; S122-R124 PolarHBondContact O-N 2.88Å; S122-E125 VanDerWaalsContact CB-OE2 3.26Å; S122-E125 WeakPolarHBondContact CB-OE2 3.28Å; S122-E125 PolarHBondContact N-OE2 2.95Å; S122-E125 PolarHBondContact O-N 2.87Å; S122-E125 WeakPolarHBondContact OG-CB 3.38Å; S122-E125 VanDerWaalsContact OG-CG 3.24Å; S122-E125 WeakPolarHBondContact OG-CG 3.46Å; S122-E125 PolarHBondContact OG-N 3.1Å; S122-E125 VanDerWaalsContact OG-N 3.09Å; S122-E125 PolarHBondContact OG-OE2 3.31Å; S122-A126 WeakPolarHBondContact O-CB 3.26Å; S122-A126 PolarHBondContact O-N 3.29Å; S122-Q145 VanDerWaalsContact CA-OE1 3.25Å
123G90.3Very high90.7Very high17 Ų1752.7 Ų52.718%0.17525%0.25CS..Hα-helixtrans-54.6-50.3170.500000111.2E125 A126 E127 R142G123-E125 PolarHBondContact O-N 3.43Å; G123-A126 WeakPolarHBondContact O-CB 3.37Å; G123-A126 PolarHBondContact O-N 3.35Å; G123-A126 VanDerWaalsContact O-N 3.14Å; G123-E127 WeakPolarHBondContact O-CG 3.4Å; G123-E127 PolarHBondContact O-N 3.09Å; G123-R142 VanDerWaalsContact CA-NH2 3.33Å
124R91.7Very high90.9Very high201 Ų20150.1 Ų50.176%0.75824%0.237SC*.Hα-helixtrans-60.2-44.3-179.5-171.8178.7-179.6-179.90.2113.6S122 A126 E127 Q128S122-R124 VanDerWaalsContact C-N 3.31Å; S122-R124 PolarHBondContact O-N 2.88Å; R124-A126 VanDerWaalsContact C-N 3.34Å; R124-E127 PolarHBondContact O-N 3.43Å; R124-Q128 PolarHBondContact O-N 3.45Å
125E90.6Very high91Very high80 Ų8055 Ų5537%0.37425%0.254SS..Hα-helixtrans-64.5-40.7175.6-71.9162.8129.400111.3I121 S122 G123 E127 Q128 L129I121-E125 HydrophobicContact CB-CB 4.43Å; S122-E125 VanDerWaalsContact CB-OE2 3.26Å; S122-E125 WeakPolarHBondContact CB-OE2 3.28Å; S122-E125 PolarHBondContact N-OE2 2.95Å; S122-E125 PolarHBondContact O-N 2.87Å; S122-E125 WeakPolarHBondContact OG-CB 3.38Å; S122-E125 VanDerWaalsContact OG-CG 3.24Å; S122-E125 WeakPolarHBondContact OG-CG 3.46Å; S122-E125 PolarHBondContact OG-N 3.1Å; S122-E125 VanDerWaalsContact OG-N 3.09Å; S122-E125 PolarHBondContact OG-OE2 3.31Å; G123-E125 PolarHBondContact O-N 3.43Å; E125-E127 VanDerWaalsContact C-N 3.33Å; E125-E127 PolarHBondContact O-N 2.89Å; E125-Q128 PolarHBondContact O-N 3.28Å; E125-L129 WeakPolarHBondContact O-CB 3.45Å; E125-L129 VanDerWaalsContact O-CG 3.29Å; E125-L129 WeakPolarHBondContact O-CG 3.49Å; E125-L129 PolarHBondContact O-N 3.36Å
126A93.9Very high91Very high0 Ų057.9 Ų57.90%027%0.27CS..Hα-helixtrans-62.9-39.8175.400000112.1I121 S122 G123 R124 L130 L140I121-A126 HydrophobicContact CD1-CB 3.83Å; S122-A126 WeakPolarHBondContact O-CB 3.26Å; S122-A126 PolarHBondContact O-N 3.29Å; G123-A126 WeakPolarHBondContact O-CB 3.37Å; G123-A126 PolarHBondContact O-N 3.35Å; G123-A126 VanDerWaalsContact O-N 3.14Å; R124-A126 VanDerWaalsContact C-N 3.34Å; A126-L130 VanDerWaalsContact O-CB 3.3Å; A126-L130 WeakPolarHBondContact O-CB 3.39Å; A126-L130 WeakPolarHBondContact O-CD1 3.39Å; A126-L130 VanDerWaalsContact O-CG 3.29Å; A126-L130 WeakPolarHBondContact O-CG 3.44Å; A126-L130 PolarHBondContact O-N 3.47Å; A126-L140 HydrophobicContact CB-CD1 3.95Å; A126-L140 HydrophobicContact CB-CD2 4.2Å
127E95.8Very high91Very high74 Ų7457.6 Ų57.635%0.34627%0.27SS..Hα-helixtrans-60.7-49.2174.2-66.1-177.7155.800111.2G123 R124 E125 L129 L130 L131 V161 H163G123-E127 WeakPolarHBondContact O-CG 3.4Å; G123-E127 PolarHBondContact O-N 3.09Å; R124-E127 PolarHBondContact O-N 3.43Å; E125-E127 VanDerWaalsContact C-N 3.33Å; E125-E127 PolarHBondContact O-N 2.89Å; E127-L129 PolarHBondContact O-N 2.8Å; E127-L130 PolarHBondContact O-N 3.48Å; E127-L131 WeakPolarHBondContact O-CB 3.38Å; E127-L131 VanDerWaalsContact O-CG 3.24Å; E127-L131 WeakPolarHBondContact O-CG 3.34Å; E127-L131 PolarHBondContact O-N 3.22Å; E127-V161 HydrophobicContact CB-CB 4.37Å; E127-V161 HydrophobicContact CB-CG2 4.35Å; E127-V161 HydrophobicContact CG-CB 3.86Å; E127-V161 HydrophobicContact CG-CG1 3.95Å; E127-V161 HydrophobicContact CG-CG2 4.38Å; E127-H163 WeakPolarHBondContact CG-NE2 3.38Å; E127-H163 IonicContact OE1-CD2 3.39Å; E127-H163 IonicContact OE1-NE2 3.44Å; E127-H163 PolarHBondContact OE1-NE2 3.41Å
128Q93.1Very high91.1Very high102 Ų10257.3 Ų57.348%0.47727%0.27SS..Hα-helixtrans-58.1-50.5178.7-174.81752.400111.6R124 E125 L130 L131 E132R124-Q128 PolarHBondContact O-N 3.45Å; E125-Q128 PolarHBondContact O-N 3.28Å; Q128-L130 PolarHBondContact O-N 3.19Å; Q128-L131 PolarHBondContact O-N 2.72Å; Q128-E132 HydrophobicContact CG-CG 4.27Å; Q128-E132 WeakPolarHBondContact CG-OE1 3.48Å; Q128-E132 PolarHBondContact NE2-OE1 2.82Å; Q128-E132 WeakPolarHBondContact O-CB 3.37Å; Q128-E132 WeakPolarHBondContact O-CG 3.23Å; Q128-E132 PolarHBondContact O-N 3.25Å
129L92.5Very high91.4Very high45 Ų4556.3 Ų56.324%0.23627%0.265CS..Hα-helixtrans-58.6-45.3178.3-72.1172.1000112.2I121 E125 E127 Q133 G134 L231I121-L129 HydrophobicContact CD1-CD1 4.09Å; E125-L129 WeakPolarHBondContact O-CB 3.45Å; E125-L129 VanDerWaalsContact O-CG 3.29Å; E125-L129 WeakPolarHBondContact O-CG 3.49Å; E125-L129 PolarHBondContact O-N 3.36Å; E127-L129 PolarHBondContact O-N 2.8Å; L129-Q133 WeakPolarHBondContact O-CB 3.38Å; L129-Q133 PolarHBondContact O-N 3.42Å; L129-G134 PolarHBondContact O-N 3.28Å; L129-L231 HydrophobicContact CB-CD2 4.05Å
130L95.4Very high92Very high0 Ų056.1 Ų56.10%026%0.263CS..Hα-helixtrans-66.9-37.9-180-79.1169.6000112.6A126 E127 Q128 G134 L140 R156 V161 L231A126-L130 VanDerWaalsContact O-CB 3.3Å; A126-L130 WeakPolarHBondContact O-CB 3.39Å; A126-L130 WeakPolarHBondContact O-CD1 3.39Å; A126-L130 VanDerWaalsContact O-CG 3.29Å; A126-L130 WeakPolarHBondContact O-CG 3.44Å; A126-L130 PolarHBondContact O-N 3.47Å; E127-L130 PolarHBondContact O-N 3.48Å; Q128-L130 PolarHBondContact O-N 3.19Å; L130-G134 CarbonylContact O-C 3.53Å; L130-G134 WeakPolarHBondContact O-CA 3.12Å; L130-G134 PolarHBondContact O-N 3.29Å; L130-L140 HydrophobicContact CD1-CD2 4.29Å; L130-L140 HydrophobicContact CD1-CG 4.31Å; L130-L140 HydrophobicContact CD2-CD2 4.36Å; L130-L140 HydrophobicContact CG-CD2 3.97Å; L130-L140 HydrophobicContact CG-CG 4.41Å; L130-R156 HydrophobicContact CB-CB 4.25Å; L130-R156 HydrophobicContact CD2-CB 4.46Å; L130-R156 WeakPolarHBondContact O-CD 3.22Å; L130-R156 PolarHBondContact O-NH1 2.98Å; L130-V161 HydrophobicContact CB-CG2 4.02Å; L130-V161 HydrophobicContact CD1-CG1 3.7Å; L130-V161 HydrophobicContact CD1-CG2 4.24Å; L130-L231 HydrophobicContact CD2-CB 4.32Å; L130-L231 HydrophobicContact CD2-CD2 4.05Å; L130-L231 HydrophobicContact CG-CD2 4.38Å
131L93.4Very high92.7Very high69 Ų6953 Ų5336%0.36125%0.251SS..Hα-helixtrans-75.4-37.7179.7-69.5172.9000112.5E127 Q128 R156 V161E127-L131 WeakPolarHBondContact O-CB 3.38Å; E127-L131 VanDerWaalsContact O-CG 3.24Å; E127-L131 WeakPolarHBondContact O-CG 3.34Å; E127-L131 PolarHBondContact O-N 3.22Å; Q128-L131 PolarHBondContact O-N 2.72Å; L131-R156 PolarHBondContact O-NH1 2.81Å; L131-V161 HydrophobicContact CD2-CG2 4.24Å; L131-V161 HydrophobicContact CG-CG2 4.07Å
132E89.5Confident93Very high127 Ų12753.4 Ų53.459%0.59325%0.251SS*.Hα-helixtrans-81.3-42.2-178.6-70.3176.7-178.200113.4Q128Q128-E132 HydrophobicContact CG-CG 4.27Å; Q128-E132 WeakPolarHBondContact CG-OE1 3.48Å; Q128-E132 PolarHBondContact NE2-OE1 2.82Å; Q128-E132 WeakPolarHBondContact O-CB 3.37Å; Q128-E132 WeakPolarHBondContact O-CG 3.23Å; Q128-E132 PolarHBondContact O-N 3.25Å
133Q88.5Confident93.1Very high116 Ų11654 Ų5454%0.54225%0.252SS..THydrogen-bonded Turntrans-113-23.6-170.8-56.2177.627.700112.9L129 L231L129-Q133 WeakPolarHBondContact O-CB 3.38Å; L129-Q133 PolarHBondContact O-N 3.42Å; Q133-L231 HydrophobicContact CB-CD1 4.08Å
134G89.4Confident92.9Very high15 Ų1553.5 Ų53.516%0.15525%0.246CC..  trans-78.2173.2176.300000113L129 L130 R156L129-G134 PolarHBondContact O-N 3.28Å; L130-G134 CarbonylContact O-C 3.53Å; L130-G134 WeakPolarHBondContact O-CA 3.12Å; L130-G134 PolarHBondContact O-N 3.29Å; G134-R156 PolarHBondContact O-NH1 3.41Å
135R92.1Very high92.4Very high149 Ų14946.9 Ų46.956%0.56222%0.223SC*.  trans-123.4170.9165.157.3-176.9176.5-168.1-3.9110.2G137 S138 F229R135-G137 PolarHBondContact O-N 3.43Å; R135-S138 WeakPolarHBondContact CG-OG 3.41Å; R135-S138 PolarHBondContact N-OG 3.32Å; R135-S138 WeakPolarHBondContact O-CB 3.3Å; R135-S138 PolarHBondContact O-N 3.06Å; R135-S138 PolarHBondContact O-OG 3.02Å; R135-F229 HydrophobicContact CG-CD2 3.61Å; R135-F229 HydrophobicContact CG-CE2 4.03Å; R135-F229 HydrophobicContact CG-CG 4.25Å; R135-F229 VanDerWaalsContact NE-CG 3.29Å
136N93.5Very high91.9Very high76 Ų7647.4 Ų47.441%0.40624%0.236SC..THydrogen-bonded Turntrans-54.4131.4177.5-172.831000111.9S138 R156 Q157 N158 F229N136-S138 VanDerWaalsContact C-N 3.32Å; N136-R156 PolarHBondContact OD1-O 2.93Å; N136-Q157 WeakPolarHBondContact OD1-CA 3.29Å; N136-N158 PolarHBondContact ND2-OD1 2.78Å; N136-N158 PolarHBondContact OD1-N 3.16Å; N136-F229 WeakPolarHBondContact O-CE2 3.25Å
137G93.4Very high91.2Very high3 Ų350 Ų503%0.03125%0.252CS..THydrogen-bonded Turntrans80.37.8-171.500000114.6R135 R156 K228 F229R135-G137 PolarHBondContact O-N 3.43Å; G137-R156 PolarHBondContact N-O 2.95Å; G137-K228 WeakPolarHBondContact O-CA 3.43Å; G137-K228 PolarHBondContact O-N 3.01Å; G137-F229 PolarHBondContact O-N 2.66Å
138S96.4Very high90.2Very high5 Ų547.8 Ų47.84%0.03524%0.244CC..EExtended strand (participates in β ladder)trans-75145.4171.5-54.90000111R135 N136 V155 R156 F229R135-S138 WeakPolarHBondContact CG-OG 3.41Å; R135-S138 PolarHBondContact N-OG 3.32Å; R135-S138 WeakPolarHBondContact O-CB 3.3Å; R135-S138 PolarHBondContact O-N 3.06Å; R135-S138 PolarHBondContact O-OG 3.02Å; N136-S138 VanDerWaalsContact C-N 3.32Å; S138-V155 WeakPolarHBondContact O-CA 3.49Å; S138-R156 PolarHBondContact O-N 3.4Å; S138-F229 CarbonylContact C-O 3.57Å; S138-F229 WeakPolarHBondContact CA-O 3.19Å
139F97.5Very high89.6Confident0 Ų043.7 Ų43.70%023%0.23CC..EExtended strand (participates in β ladder)trans-143.6158.2-176.971.9-87.5000112.4W116 L153 S154 V155 V209 R213 L227 F229 P230 L231W116-F139 HydrophobicContact CB-CE2 4.11Å; W116-F139 HydrophobicContact CD2-CE2 4.47Å; W116-F139 HydrophobicContact CG-CE2 4.1Å; F139-L153 HydrophobicContact CB-CD1 4.21Å; F139-L153 HydrophobicContact CD2-CD1 3.84Å; F139-L153 HydrophobicContact CG-CD1 4.4Å; F139-S154 CarbonylContact C-O 3.52Å; F139-S154 WeakPolarHBondContact CA-O 3.14Å; F139-V155 HydrophobicContact CB-CB 4.49Å; F139-V155 HydrophobicContact CB-CG1 4.37Å; F139-V155 HydrophobicContact CB-CG2 4.09Å; F139-V209 HydrophobicContact CE2-CG1 3.66Å; F139-V209 HydrophobicContact CZ-CG1 3.79Å; F139-R213 HydrophobicContact CZ-CG 4.45Å; F139-L227 HydrophobicContact CB-CD2 3.91Å; F139-L227 HydrophobicContact CD1-CB 3.82Å; F139-L227 HydrophobicContact CD1-CD2 4.34Å; F139-L227 HydrophobicContact CE1-CB 3.95Å; F139-L227 HydrophobicContact CG-CB 4.28Å; F139-L227 HydrophobicContact CG-CD2 4.03Å; F139-F229 WeakPolarHBondContact CD1-O 3.45Å; F139-F229 PolarHBondContact N-O 3.46Å; F139-P230 HydrophobicContact CE1-CB 4.06Å; F139-P230 HydrophobicContact CE2-CB 4.3Å; F139-P230 HydrophobicContact CZ-CB 3.76Å; F139-P230 HydrophobicContact CZ-CG 4.47Å; F139-L231 PolarHBondContact O-N 3.26Å
140L97.4Very high89.5Confident0 Ų042.8 Ų42.80%023%0.225CC..EExtended strand (participates in β ladder)trans-144.5158.1168.664.583.1000110W116 H118 I121 A126 L130 R142 S154 L231W116-L140 WeakPolarHBondContact O-CA 3.47Å; H118-L140 HydrophobicContact CB-CD1 4.5Å; I121-L140 HydrophobicContact CD1-CD1 3.93Å; I121-L140 HydrophobicContact CD1-CD2 4.21Å; A126-L140 HydrophobicContact CB-CD1 3.95Å; A126-L140 HydrophobicContact CB-CD2 4.2Å; L130-L140 HydrophobicContact CD1-CD2 4.29Å; L130-L140 HydrophobicContact CD1-CG 4.31Å; L130-L140 HydrophobicContact CD2-CD2 4.36Å; L130-L140 HydrophobicContact CG-CD2 3.97Å; L130-L140 HydrophobicContact CG-CG 4.41Å; L140-R142 HydrophobicContact CD1-CB 4.14Å; L140-R142 HydrophobicContact CD1-CG 4.26Å; L140-S154 PolarHBondContact N-O 2.76Å; L140-S154 PolarHBondContact O-N 2.91Å; L140-L231 HydrophobicContact CD2-CD2 4.19Å
141V96.9Very high89.4Confident1 Ų143.7 Ų43.71%0.00623%0.228CC..EExtended strand (participates in β ladder)trans-112.3140.5170.8-178.90000108.9W116 F117 H118 A152 L153 L205 V209W116-V141 HydrophobicContact CE3-CB 3.55Å; W116-V141 HydrophobicContact CE3-CG2 3.39Å; W116-V141 HydrophobicContact CH2-CG2 4.49Å; W116-V141 HydrophobicContact CZ3-CB 3.5Å; W116-V141 HydrophobicContact CZ3-CG1 4.1Å; W116-V141 HydrophobicContact CZ3-CG2 3.37Å; W116-V141 PolarHBondContact O-N 2.95Å; F117-V141 CarbonylContact C-O 3.48Å; F117-V141 WeakPolarHBondContact CA-O 3.01Å; F117-V141 HydrophobicContact CD2-CB 4.22Å; F117-V141 HydrophobicContact CD2-CG1 4Å; F117-V141 HydrophobicContact CE2-CG1 4.42Å; H118-V141 PolarHBondContact N-O 2.79Å; V141-A152 WeakPolarHBondContact CA-O 3.44Å; V141-L153 HydrophobicContact CG2-CB 4.48Å; V141-L153 HydrophobicContact CG2-CD1 3.74Å; V141-L205 HydrophobicContact CG1-CD1 4.39Å; V141-V209 HydrophobicContact CG2-CG2 4.06Å
142R93.8Very high89.5Confident20 Ų2040.6 Ų40.68%0.07521%0.213CC..EExtended strand (participates in β ladder)trans-139.7163.1-179.461.6-173.9-178.478.20.8110.4G119 I121 G123 L140 Y151 A152 S154G119-R142 CarbonylContact O-C 3.49Å; G119-R142 WeakPolarHBondContact O-CA 3.24Å; G119-R142 WeakPolarHBondContact O-CB 3.03Å; I121-R142 HydrophobicContact CD1-CB 4.34Å; I121-R142 HydrophobicContact CG1-CB 3.64Å; I121-R142 HydrophobicContact CG1-CG 4.36Å; I121-R142 WeakPolarHBondContact O-CD 3.11Å; I121-R142 PolarHBondContact O-NH1 3.02Å; G123-R142 VanDerWaalsContact CA-NH2 3.33Å; L140-R142 HydrophobicContact CD1-CB 4.14Å; L140-R142 HydrophobicContact CD1-CG 4.26Å; R142-Y151 CarbonylContact O-C 3.57Å; R142-Y151 VanDerWaalsContact O-CA 3.27Å; R142-Y151 WeakPolarHBondContact O-CA 3.24Å; R142-Y151 WeakPolarHBondContact O-CB 3.43Å; R142-A152 HydrophobicContact CG-CB 3.97Å; R142-A152 PolarHBondContact N-O 2.86Å; R142-A152 PolarHBondContact O-N 2.82Å; R142-S154 PolarHBondContact NE-OG 2.84Å; R142-S154 VanDerWaalsContact NE-OG 3.16Å
143E89.2Confident89.8Confident33 Ų3334.5 Ų34.515%0.15418%0.184CC..EExtended strand (participates in β ladder)trans-65.5144.4167.6-68.2179.4-16400110.6F117 G119 Y120 Q145 Y151F117-E143 HydrophobicContact CZ-CG 4.1Å; G119-E143 PolarHBondContact O-N 3.47Å; Y120-E143 HydrophobicContact CD2-CB 4.37Å; E143-Q145 PolarHBondContact O-N 2.94Å; E143-Y151 HydrophobicContact CG-CD1 4.31Å; E143-Y151 HydrophobicContact CG-CE1 4.07Å
144S88Confident90.2Very high7 Ų729 Ų295%0.04916%0.159CC..  trans-77.7120.2173.3-178.20000110.1S146 T147 D150S144-S146 PolarHBondContact OG-OG 2.82Å; S144-T147 WeakPolarHBondContact CB-O 3.17Å; S144-T147 PolarHBondContact OG-N 2.89Å; S144-T147 VanDerWaalsContact OG-N 3.1Å; S144-D150 VanDerWaalsContact CB-O 3.26Å; S144-D150 WeakPolarHBondContact CB-O 3.5Å; S144-D150 PolarHBondContact N-O 3.43Å
145Q81.4Confident90.6Very high62 Ų6228.3 Ų28.329%0.2915%0.152SC..SBendtrans-76.6-28.5174.7-72.2-173.8-27.600112.3R8 Y120 S122 E143R8-Q145 PolarHBondContact NH1-O 3.41Å; Y120-Q145 HydrophobicContact CE2-CG 3.9Å; S122-Q145 VanDerWaalsContact CA-OE1 3.25Å; E143-Q145 PolarHBondContact O-N 2.94Å
146S78.9Confident90.7Very high92 Ų9223.2 Ų23.264%0.64313%0.132SC*.SBendtrans-79.8-33.1178.157.10000112.7S144S144-S146 PolarHBondContact OG-OG 2.82Å
147T79.6Confident90.6Very high54 Ų5420.3 Ų20.333%0.33112%0.116SC..SBendtrans-128.695.5-173.3-460000110.2S144 G149 D150S144-T147 WeakPolarHBondContact CB-O 3.17Å; S144-T147 PolarHBondContact OG-N 2.89Å; S144-T147 VanDerWaalsContact OG-N 3.1Å; T147-G149 PolarHBondContact O-N 2.91Å; T147-D150 HydrophobicContact CG2-CB 4.12Å; T147-D150 WeakPolarHBondContact CG2-OD2 3.25Å; T147-D150 PolarHBondContact O-N 3.4Å; T147-D150 VanDerWaalsContact O-N 3.14Å
148P75.4Confident90.2Very high27 Ų2725.2 Ų25.218%0.17514%0.142CC..THydrogen-bonded Turntrans-55.6129.3-178.1-24.832.8000113.2F11 L78 D150F11-P148 HydrophobicContact CD1-CB 4.46Å; F11-P148 HydrophobicContact CE1-CB 4.34Å; F11-P148 HydrophobicContact CZ-CB 4.44Å; L78-P148 HydrophobicContact CD1-CB 4.45Å; L78-P148 HydrophobicContact CD1-CG 4.27Å; P148-D150 VanDerWaalsContact C-N 3.32Å
149G79.1Confident89.7Confident17 Ų1731.9 Ų31.918%0.17518%0.177CC..THydrogen-bonded Turntrans93.8-20.8-178.700000114.9F11 T147 Y151 F168F11-G149 VanDerWaalsContact CE1-CA 3.5Å; T147-G149 PolarHBondContact O-N 2.91Å; G149-Y151 VanDerWaalsContact O-CE2 3.3Å; G149-Y151 WeakPolarHBondContact O-CE2 3.39Å; G149-F168 WeakPolarHBondContact O-CB 3.35Å
150D90.1Very high89.5Confident26 Ų2637.7 Ų37.714%0.13920%0.199CC..  trans-88.3170.4172.8-72.5-14.6000111S144 T147 P148 M165 R167 F168S144-D150 VanDerWaalsContact CB-O 3.26Å; S144-D150 WeakPolarHBondContact CB-O 3.5Å; S144-D150 PolarHBondContact N-O 3.43Å; T147-D150 HydrophobicContact CG2-CB 4.12Å; T147-D150 WeakPolarHBondContact CG2-OD2 3.25Å; T147-D150 PolarHBondContact O-N 3.4Å; T147-D150 VanDerWaalsContact O-N 3.14Å; P148-D150 VanDerWaalsContact C-N 3.32Å; D150-M165 HydrophobicContact CB-SD 4.13Å; D150-R167 WeakPolarHBondContact OD1-CA 3.36Å; D150-F168 PolarHBondContact OD1-N 3.11Å
151Y94.1Very high89.3Confident18 Ų1838.6 Ų38.67%0.07120%0.204CC..EExtended strand (participates in β ladder)trans-126.2165.4-177-58.3-87000110.1P111 F117 R142 E143 G149 V166 F168 Y194 L205P111-Y151 HydrophobicContact CG-CE1 3.69Å; P111-Y151 WeakPolarHBondContact CG-OH 3.42Å; F117-Y151 AromaticContact CE2-CD1 3.8Å; F117-Y151 HydrophobicContact CE2-CD1 3.8Å; F117-Y151 AromaticContact CE2-CE1 3.85Å; F117-Y151 HydrophobicContact CE2-CE1 3.85Å; F117-Y151 HydrophobicContact CZ-CD1 4.4Å; F117-Y151 HydrophobicContact CZ-CE1 4.03Å; R142-Y151 CarbonylContact O-C 3.57Å; R142-Y151 VanDerWaalsContact O-CA 3.27Å; R142-Y151 WeakPolarHBondContact O-CA 3.24Å; R142-Y151 WeakPolarHBondContact O-CB 3.43Å; E143-Y151 HydrophobicContact CG-CD1 4.31Å; E143-Y151 HydrophobicContact CG-CE1 4.07Å; G149-Y151 VanDerWaalsContact O-CE2 3.3Å; G149-Y151 WeakPolarHBondContact O-CE2 3.39Å; Y151-V166 PolarHBondContact N-O 2.9Å; Y151-V166 PolarHBondContact O-N 3.15Å; Y151-F168 HydrophobicContact CE2-CB 4.35Å; Y151-Y194 HydrophobicContact CD2-CD1 4.19Å; Y151-Y194 AromaticContact CD2-CE1 3.88Å; Y151-Y194 HydrophobicContact CD2-CE1 3.88Å; Y151-Y194 HydrophobicContact CE2-CD1 4.31Å; Y151-Y194 AromaticContact CE2-CE1 3.56Å; Y151-Y194 HydrophobicContact CE2-CE1 3.56Å; Y151-L205 HydrophobicContact CD1-CD1 4.13Å; Y151-L205 HydrophobicContact CD2-CD1 4.41Å; Y151-L205 HydrophobicContact CD2-CD2 4.26Å; Y151-L205 HydrophobicContact CE1-CD1 4.19Å; Y151-L205 HydrophobicContact CE2-CD1 4.49Å; Y151-L205 HydrophobicContact CG-CD1 4.23Å; Y151-L205 HydrophobicContact CG-CD2 4.33Å
152A94.7Very high89.2Confident4 Ų439.7 Ų39.73%0.03321%0.211CC..EExtended strand (participates in β ladder)trans-129.5131.1172.200000109.8V141 R142 V164V141-A152 WeakPolarHBondContact CA-O 3.44Å; R142-A152 HydrophobicContact CG-CB 3.97Å; R142-A152 PolarHBondContact N-O 2.86Å; R142-A152 PolarHBondContact O-N 2.82Å; A152-V164 CarbonylContact C-O 3.46Å; A152-V164 WeakPolarHBondContact CA-O 3.24Å
153L96Very high89.1Confident0 Ų042 Ų420%022%0.222CC..EExtended strand (participates in β ladder)trans-95.4108.4170.7171.862.3000108F139 V141 V155 V164 V166 M217 L227F139-L153 HydrophobicContact CB-CD1 4.21Å; F139-L153 HydrophobicContact CD2-CD1 3.84Å; F139-L153 HydrophobicContact CG-CD1 4.4Å; V141-L153 HydrophobicContact CG2-CB 4.48Å; V141-L153 HydrophobicContact CG2-CD1 3.74Å; L153-V155 HydrophobicContact CD1-CG2 4.26Å; L153-V155 HydrophobicContact CG-CG2 3.95Å; L153-V164 HydrophobicContact CB-CB 4.28Å; L153-V164 PolarHBondContact N-O 2.91Å; L153-V164 PolarHBondContact O-N 3.27Å; L153-V166 HydrophobicContact CB-CG2 3.91Å; L153-M217 HydrophobicContact CD2-CE 3.54Å; L153-L227 HydrophobicContact CD1-CD1 4.38Å; L153-L227 HydrophobicContact CD1-CD2 4.08Å; L153-L227 HydrophobicContact CD2-CD1 3.81Å; L153-L227 HydrophobicContact CD2-CD2 3.99Å; L153-L227 HydrophobicContact CD2-CG 4.5Å; L153-L227 HydrophobicContact CG-CD2 4.27Å
154S97.3Very high89.3Confident0 Ų041.7 Ų41.70%022%0.223CC..EExtended strand (participates in β ladder)trans-97.6127.3-180-48.60000109.2F139 L140 R142 T162 H163F139-S154 CarbonylContact C-O 3.52Å; F139-S154 WeakPolarHBondContact CA-O 3.14Å; L140-S154 PolarHBondContact N-O 2.76Å; L140-S154 PolarHBondContact O-N 2.91Å; R142-S154 PolarHBondContact NE-OG 2.84Å; R142-S154 VanDerWaalsContact NE-OG 3.16Å; S154-T162 CarbonylContact C-O 3.55Å; S154-T162 WeakPolarHBondContact CA-O 3.45Å; S154-H163 WeakPolarHBondContact CB-ND1 3.43Å; S154-H163 PolarHBondContact OG-ND1 3.09Å
155V96.9Very high89.6Confident1 Ų144.9 Ų44.91%0.00624%0.238CC..EExtended strand (participates in β ladder)trans-131.1125.6-172.8-169.50000110.3S138 F139 L153 Q157 V161 T162 V225 L227S138-V155 WeakPolarHBondContact O-CA 3.49Å; F139-V155 HydrophobicContact CB-CB 4.49Å; F139-V155 HydrophobicContact CB-CG1 4.37Å; F139-V155 HydrophobicContact CB-CG2 4.09Å; L153-V155 HydrophobicContact CD1-CG2 4.26Å; L153-V155 HydrophobicContact CG-CG2 3.95Å; V155-Q157 PolarHBondContact O-N 2.8Å; V155-V161 CarbonylContact O-C 3.56Å; V155-V161 WeakPolarHBondContact O-CA 3.3Å; V155-T162 PolarHBondContact N-O 3.35Å; V155-T162 PolarHBondContact O-N 2.75Å; V155-V225 HydrophobicContact CB-CG1 3.89Å; V155-V225 HydrophobicContact CG1-CG1 3.84Å; V155-V225 HydrophobicContact CG2-CG1 3.78Å; V155-L227 HydrophobicContact CB-CD2 4.41Å; V155-L227 HydrophobicContact CG1-CD2 4.08Å; V155-L227 HydrophobicContact CG2-CD2 3.41Å; V155-L227 VanDerWaalsContact CG2-CD2 3.41Å
156R95.7Very high90.2Very high41 Ų4141.9 Ų41.916%0.15522%0.224CC..EExtended strand (participates in β ladder)trans-75.8120.5172.5-178.4168.6174.51744.8110.7L130 L131 G134 N136 G137 S138 N158 V161L130-R156 HydrophobicContact CB-CB 4.25Å; L130-R156 HydrophobicContact CD2-CB 4.46Å; L130-R156 WeakPolarHBondContact O-CD 3.22Å; L130-R156 PolarHBondContact O-NH1 2.98Å; L131-R156 PolarHBondContact O-NH1 2.81Å; G134-R156 PolarHBondContact O-NH1 3.41Å; N136-R156 PolarHBondContact OD1-O 2.93Å; G137-R156 PolarHBondContact N-O 2.95Å; S138-R156 PolarHBondContact O-N 3.4Å; R156-N158 PolarHBondContact NE-O 2.81Å; R156-V161 HydrophobicContact CB-CG2 4.48Å
157Q91.1Very high90.8Very high16 Ų1643 Ų438%0.07521%0.214CC..EExtended strand (participates in β ladder)trans-117102.1170.2-66.7179.9-12.800108.8N136 V155 N159 R160 T162 E219 V225N136-Q157 WeakPolarHBondContact OD1-CA 3.29Å; V155-Q157 PolarHBondContact O-N 2.8Å; Q157-N159 PolarHBondContact O-N 3.42Å; Q157-R160 CarbonylContact C-O 3.5Å; Q157-R160 HydrophobicContact CB-CG 4.19Å; Q157-R160 PolarHBondContact N-O 3.3Å; Q157-R160 WeakPolarHBondContact O-CG 3.43Å; Q157-R160 PolarHBondContact O-N 2.72Å; Q157-R160 VanDerWaalsContact O-O 3.06Å; Q157-R160 VanDerWaalsContact OE1-NE 3.1Å; Q157-T162 PolarHBondContact OE1-OG1 2.7Å; Q157-T162 VanDerWaalsContact OE1-OG1 3.13Å; Q157-E219 PolarHBondContact NE2-OE1 3.32Å; Q157-E219 VanDerWaalsContact NE2-OE1 3.11Å; Q157-E219 PolarHBondContact OE1-OE1 3.32Å; Q157-V225 VanDerWaalsContact NE2-CG2 3.31Å
158N85.6Confident91.2Very high105 Ų10541.5 Ų41.556%0.56120%0.203SC*.THydrogen-bonded Turntrans54.6-106.2-176.5-56.5-36.6000111.5N136 R156N136-N158 PolarHBondContact ND2-OD1 2.78Å; N136-N158 PolarHBondContact OD1-N 3.16Å; R156-N158 PolarHBondContact NE-O 2.81Å
159N85.7Confident91.7Very high145 Ų14542.8 Ų42.878%0.77521%0.21SC*.THydrogen-bonded Turntrans-107.19.1-178.1-67.9-11.2000113.6Q157Q157-N159 PolarHBondContact O-N 3.42Å
160R91.6Very high91.8Very high123 Ų12343.9 Ų43.946%0.46421%0.214SC..EExtended strand (participates in β ladder)trans-124.6162.8173.570.1178.6-168.6-17310.8110.6Q157 E219Q157-R160 CarbonylContact C-O 3.5Å; Q157-R160 HydrophobicContact CB-CG 4.19Å; Q157-R160 PolarHBondContact N-O 3.3Å; Q157-R160 WeakPolarHBondContact O-CG 3.43Å; Q157-R160 PolarHBondContact O-N 2.72Å; Q157-R160 VanDerWaalsContact O-O 3.06Å; Q157-R160 VanDerWaalsContact OE1-NE 3.1Å; R160-E219 IonicContact NH2-OE1 2.85Å; R160-E219 IonicContact NH2-OE2 3.52Å; R160-E219 PolarHBondContact NH2-OE2 2.98Å
161V94.6Very high91.3Very high19 Ų1946.4 Ų46.412%0.11522%0.223CC..EExtended strand (participates in β ladder)trans-119.4126.7173.5172.50000107.9E127 L130 L131 V155 R156E127-V161 HydrophobicContact CB-CB 4.37Å; E127-V161 HydrophobicContact CB-CG2 4.35Å; E127-V161 HydrophobicContact CG-CB 3.86Å; E127-V161 HydrophobicContact CG-CG1 3.95Å; E127-V161 HydrophobicContact CG-CG2 4.38Å; L130-V161 HydrophobicContact CB-CG2 4.02Å; L130-V161 HydrophobicContact CD1-CG1 3.7Å; L130-V161 HydrophobicContact CD1-CG2 4.24Å; L131-V161 HydrophobicContact CD2-CG2 4.24Å; L131-V161 HydrophobicContact CG-CG2 4.07Å; V155-V161 CarbonylContact O-C 3.56Å; V155-V161 WeakPolarHBondContact O-CA 3.3Å; R156-V161 HydrophobicContact CB-CG2 4.48Å
162T93.3Very high90.5Very high23 Ų2352.6 Ų52.614%0.14125%0.25CS..EExtended strand (participates in β ladder)trans-96.4133.3174.3-60.80000108.2S154 V155 Q157 V164 E219S154-T162 CarbonylContact C-O 3.55Å; S154-T162 WeakPolarHBondContact CA-O 3.45Å; V155-T162 PolarHBondContact N-O 3.35Å; V155-T162 PolarHBondContact O-N 2.75Å; Q157-T162 PolarHBondContact OE1-OG1 2.7Å; Q157-T162 VanDerWaalsContact OE1-OG1 3.13Å; T162-V164 HydrophobicContact CG2-CG2 4.27Å; T162-E219 VanDerWaalsContact CG2-OE1 3.3Å; T162-E219 WeakPolarHBondContact CG2-OE1 3.48Å; T162-E219 PolarHBondContact OG1-OE1 3.14Å
163H93.6Very high89.6Confident68 Ų6854.7 Ų54.732%0.31526%0.263SS..EExtended strand (participates in β ladder)trans-106.4120172.5-58.8-70.8000109.9E127 S154E127-H163 WeakPolarHBondContact CG-NE2 3.38Å; E127-H163 IonicContact OE1-CD2 3.39Å; E127-H163 IonicContact OE1-NE2 3.44Å; E127-H163 PolarHBondContact OE1-NE2 3.41Å; S154-H163 WeakPolarHBondContact CB-ND1 3.43Å; S154-H163 PolarHBondContact OG-ND1 3.09Å
164V92.9Very high88.7Confident28 Ų2858.5 Ų58.517%0.1728%0.283CS..EExtended strand (participates in β ladder)trans-103.9124175.5-177.90000108.6A152 L153 T162 V166 V196 M217A152-V164 CarbonylContact C-O 3.46Å; A152-V164 WeakPolarHBondContact CA-O 3.24Å; L153-V164 HydrophobicContact CB-CB 4.28Å; L153-V164 PolarHBondContact N-O 2.91Å; L153-V164 PolarHBondContact O-N 3.27Å; T162-V164 HydrophobicContact CG2-CG2 4.27Å; V164-V166 PolarHBondContact O-N 2.96Å; V164-V196 HydrophobicContact CG1-CB 4.05Å; V164-V196 HydrophobicContact CG1-CG1 3.99Å; V164-M217 HydrophobicContact CG1-SD 3.96Å; V164-M217 HydrophobicContact CG2-CE 4.2Å; V164-M217 HydrophobicContact CG2-SD 4.38Å
165M93.2Very high87.7Confident73 Ų7364.5 Ų64.536%0.3631%0.306SS..EExtended strand (participates in β ladder)trans-69.7130.9174.8-170.564.172.400109.8D150 R167D150-M165 HydrophobicContact CB-SD 4.13Å; M165-R167 HydrophobicContact CG-CG 4.24Å
166V94.2Very high86.7Confident0 Ų068.8 Ų68.80%033%0.328CS..EExtended strand (participates in β ladder)trans-113102.6173.9176.70000106.9Y151 L153 V164 Y194 D195 V196 L205 L208Y151-V166 PolarHBondContact N-O 2.9Å; Y151-V166 PolarHBondContact O-N 3.15Å; L153-V166 HydrophobicContact CB-CG2 3.91Å; V164-V166 PolarHBondContact O-N 2.96Å; V166-Y194 HydrophobicContact CG1-CD1 4.28Å; V166-D195 CarbonylContact C-O 3.59Å; V166-D195 WeakPolarHBondContact CA-O 3.43Å; V166-V196 HydrophobicContact CG2-CG1 3.93Å; V166-L205 HydrophobicContact CG1-CD2 3.78Å; V166-L208 HydrophobicContact CG1-CD1 3.69Å; V166-L208 HydrophobicContact CG2-CD2 4.46Å
167R91.4Very high85.4Confident115 Ų11570.5 Ų70.543%0.43434%0.339SS..EExtended strand (participates in β ladder)trans-77.6139.5-179.6-63.5-175.9-61.3-172.10.9110.3D150 M165 V169 Y194 D195D150-R167 WeakPolarHBondContact OD1-CA 3.36Å; M165-R167 HydrophobicContact CG-CG 4.24Å; R167-V169 HydrophobicContact CB-CG2 4.21Å; R167-Y194 WeakPolarHBondContact O-CA 3.29Å; R167-D195 IonicContact CZ-OD1 3.41Å; R167-D195 VanDerWaalsContact CZ-OD1 3.32Å; R167-D195 PolarHBondContact N-O 3.41Å; R167-D195 IonicContact NE-OD1 3.7Å; R167-D195 PolarHBondContact NE-OD1 3.33Å; R167-D195 IonicContact NE-OD2 2.72Å; R167-D195 IonicContact NH2-OD1 3.08Å; R167-D195 PolarHBondContact NH2-OD1 3.26Å; R167-D195 PolarHBondContact O-N 2.96Å
168F88.4Confident84.2Confident22 Ų2277.6 Ų77.610%0.09638%0.377CS..EExtended strand (participates in β ladder)trans-104.5107.3170.9-178.7-99.7000110.3P13 C14 G149 D150 Y151 V170 R193 Y194P13-F168 HydrophobicContact CB-CD1 3.75Å; P13-F168 HydrophobicContact CB-CE1 3.98Å; P13-F168 HydrophobicContact CG-CD1 4.26Å; P13-F168 HydrophobicContact CG-CE1 4.28Å; C14-F168 HydrophobicContact CB-CE1 4.43Å; C14-F168 WeakPolarHBondContact SG-CE1 3.36Å; C14-F168 WeakPolarHBondContact SG-CZ 3.27Å; G149-F168 WeakPolarHBondContact O-CB 3.35Å; D150-F168 PolarHBondContact OD1-N 3.11Å; Y151-F168 HydrophobicContact CE2-CB 4.35Å; F168-V170 HydrophobicContact CE1-CG2 3.88Å; F168-R193 CarbonylContact C-O 3.59Å; F168-R193 WeakPolarHBondContact CA-O 3.31Å; F168-R193 WeakPolarHBondContact CD2-O 3.18Å; F168-Y194 HydrophobicContact CB-CD1 4.43Å; F168-Y194 HydrophobicContact CB-CE1 4.39Å; F168-Y194 AromaticContact CD2-CD1 3.69Å; F168-Y194 HydrophobicContact CD2-CD1 3.69Å; F168-Y194 HydrophobicContact CD2-CD2 4.32Å; F168-Y194 AromaticContact CD2-CE1 3.33Å; F168-Y194 HydrophobicContact CD2-CE1 3.33Å; F168-Y194 AromaticContact CD2-CE2 3.99Å; F168-Y194 HydrophobicContact CD2-CE2 3.99Å; F168-Y194 HydrophobicContact CD2-CG 4.18Å; F168-Y194 AromaticContact CD2-CZ 3.49Å; F168-Y194 VanDerWaalsContact CD2-CZ 3.49Å; F168-Y194 HydrophobicContact CE2-CD2 4.48Å; F168-Y194 AromaticContact CE2-CE1 3.99Å; F168-Y194 HydrophobicContact CE2-CE1 3.99Å; F168-Y194 AromaticContact CE2-CE2 3.9Å; F168-Y194 HydrophobicContact CE2-CE2 3.9Å; F168-Y194 AromaticContact CE2-CZ 3.62Å; F168-Y194 HydrophobicContact CG-CE1 4.22Å
169V85.4Confident83Confident55 Ų5574.9 Ų74.933%0.33337%0.366SS..EExtended strand (participates in β ladder)trans-112.8125.4-173.9-176.90000110.4R167 K171 R193 D195R167-V169 HydrophobicContact CB-CG2 4.21Å; V169-K171 HydrophobicContact CG1-CG 4.31Å; V169-K171 PolarHBondContact O-N 3.18Å; V169-R193 PolarHBondContact N-O 3.01Å; V169-R193 PolarHBondContact O-N 2.89Å; V169-D195 VanDerWaalsContact CG2-OD2 3.24Å; V169-D195 WeakPolarHBondContact CG2-OD2 3.31Å
170V81.3Confident82Confident40 Ų4073.6 Ų73.624%0.24238%0.376CS..EExtended strand (participates in β ladder)trans-83.9106.4174.1-179.60000109.4F168 Q190F168-V170 HydrophobicContact CE1-CG2 3.88Å; V170-Q190 HydrophobicContact CG1-CB 3.95Å; V170-Q190 HydrophobicContact CG1-CG 4.44Å
171K80.2Confident80.9Confident79 Ų7977.4 Ų77.434%0.34340%0.396SS..EExtended strand (participates in β ladder)trans-92.6131.7177.2-65.7-166.4-177.6-176.90111.4V169 Q190 N191 R193 D201V169-K171 HydrophobicContact CG1-CG 4.31Å; V169-K171 PolarHBondContact O-N 3.18Å; K171-Q190 WeakPolarHBondContact O-CA 3.49Å; K171-N191 PolarHBondContact N-O 3.32Å; K171-N191 PolarHBondContact O-N 3.15Å; K171-N191 VanDerWaalsContact O-N 3.1Å; K171-R193 HydrophobicContact CB-CG 4.3Å; K171-R193 HydrophobicContact CD-CG 4.1Å; K171-R193 HydrophobicContact CG-CG 4.08Å; K171-D201 VanDerWaalsContact NZ-CG 3.32Å; K171-D201 IonicContact NZ-OD1 2.64Å; K171-D201 IonicContact NZ-OD2 3.5Å; K171-D201 PolarHBondContact NZ-OD2 2.75Å
172K76.9Confident79.4Confident147 Ų14779.9 Ų79.964%0.63941%0.411SS*.EExtended strand (participates in β ladder)trans-80.1118.9167.3-76.8177-178.31750109.1W188 Q190K172-W188 HydrophobicContact CB-CE3 4.14Å; K172-W188 HydrophobicContact CB-CZ3 4.44Å; K172-Q190 HydrophobicContact CG-CG 3.78Å
173T76.2Confident78.2Confident48 Ų4886.9 Ų86.929%0.29445%0.447SS..EExtended strand (participates in β ladder)trans-122.1127.7178.8-49.30000109.9R175 T189T173-R175 PolarHBondContact O-N 2.98Å; T173-T189 PolarHBondContact N-O 2.9Å; T173-T189 PolarHBondContact O-N 2.84Å; T173-T189 PolarHBondContact O-OG1 3.34Å; T173-T189 VanDerWaalsContact O-OG1 3.11Å
174L77.9Confident76.8Confident80 Ų8089.2 Ų89.242%0.41946%0.461SS..EExtended strand (participates in β ladder)trans-74.1117.2172.3-165.970.5000109.3F186 W188L174-F186 HydrophobicContact CD1-CB 3.62Å; L174-F186 HydrophobicContact CD1-CG 4.45Å; L174-F186 HydrophobicContact CD2-CB 4.02Å; L174-F186 HydrophobicContact CD2-CD1 3.92Å; L174-F186 HydrophobicContact CD2-CG 3.99Å; L174-F186 HydrophobicContact CG-CB 3.72Å; L174-F186 HydrophobicContact CG-CD1 3.88Å; L174-F186 HydrophobicContact CG-CG 4.06Å; L174-W188 HydrophobicContact CB-CD2 4.47Å; L174-W188 HydrophobicContact CB-CE3 4.09Å; L174-W188 HydrophobicContact CB-CH2 4.23Å; L174-W188 HydrophobicContact CB-CZ3 3.97Å; L174-W188 HydrophobicContact CD1-CD2 3.75Å; L174-W188 HydrophobicContact CD1-CE3 4.23Å; L174-W188 HydrophobicContact CD1-CG 4.08Å; L174-W188 HydrophobicContact CD1-CH2 4.45Å; L174-W188 HydrophobicContact CD1-CZ2 3.99Å
175R74.8Confident75.7Confident127 Ų12791 Ų9148%0.47947%0.473SS..EExtended strand (participates in β ladder)trans-109134.9173.6-78.1-164.9-164.9-1366.1110.8T173 F186 I187 T189 N191T173-R175 PolarHBondContact O-N 2.98Å; R175-F186 CarbonylContact O-C 3.56Å; R175-F186 VanDerWaalsContact O-CA 3.3Å; R175-F186 WeakPolarHBondContact O-CA 3.31Å; R175-I187 PolarHBondContact N-O 2.92Å; R175-I187 PolarHBondContact O-N 3.43Å; R175-T189 HydrophobicContact CB-CG2 4.07Å; R175-T189 HydrophobicContact CG-CG2 4.05Å; R175-N191 PolarHBondContact NH2-ND2 3.12Å
176L77.4Confident74.7Confident90 Ų9092.3 Ų92.347%0.47148%0.477SS..EExtended strand (participates in β ladder)trans-73.3124.3165.6-173.576.3000108.8L178 P185 F186L176-L178 HydrophobicContact CD2-CD2 3.94Å; L176-L178 HydrophobicContact CD2-CG 4.15Å; L176-L178 HydrophobicContact CG-CD2 4.48Å; L176-P185 CarbonylContact C-O 3.56Å; L176-P185 VanDerWaalsContact CA-O 3.32Å; L176-P185 WeakPolarHBondContact CA-O 3.21Å; L176-P185 HydrophobicContact CD1-CB 3.71Å; L176-P185 WeakPolarHBondContact CD1-O 3.47Å; L176-F186 HydrophobicContact CB-CD1 3.95Å; L176-F186 HydrophobicContact CB-CE1 3.73Å; L176-F186 HydrophobicContact CD1-CD1 3.98Å; L176-F186 HydrophobicContact CD1-CD2 4.34Å; L176-F186 HydrophobicContact CD1-CE1 3.59Å; L176-F186 HydrophobicContact CD1-CE2 3.95Å; L176-F186 HydrophobicContact CD1-CG 4.34Å; L176-F186 HydrophobicContact CD1-CZ 3.56Å; L176-F186 HydrophobicContact CG-CE1 4.24Å
177I68.6Low73.7Confident78 Ų7896 Ų9640%0.450%0.496SS..  trans-103.8107.7167.9-57.2-170.5000107.5S179 P185 I187I177-S179 PolarHBondContact O-N 3.46Å; I177-P185 PolarHBondContact N-O 2.88Å; I177-I187 HydrophobicContact CD1-CB 4.18Å; I177-I187 HydrophobicContact CD1-CD1 3.45Å; I177-I187 VanDerWaalsContact CD1-CD1 3.45Å; I177-I187 HydrophobicContact CD1-CG1 3.84Å; I177-I187 HydrophobicContact CG1-CD1 4.38Å; I177-I187 HydrophobicContact CG1-CG1 4.29Å
178L64.8Low72.5Confident164 Ų16498.7 Ų98.786%0.85951%0.506SS*.  trans-73.282.5167.8-66.9171.5000108.4L176L176-L178 HydrophobicContact CD2-CD2 3.94Å; L176-L178 HydrophobicContact CD2-CG 4.15Å; L176-L178 HydrophobicContact CG-CD2 4.48Å
179S61.6Low71.5Confident49 Ų4999.2 Ų99.234%0.34351%0.511SS..  trans-121.9128164.289.70000108.9I177 K181 V182I177-S179 PolarHBondContact O-N 3.46Å; S179-K181 PolarHBondContact O-N 3.39Å; S179-V182 PolarHBondContact O-N 2.84Å; S179-V182 WeakPolarHBondContact OG-CB 3.47Å; S179-V182 WeakPolarHBondContact OG-CG2 3.09Å
180A64.4Low70.6Confident118 Ų118100.7 Ų100.798%0.97551%0.514SS*.THydrogen-bonded Turntrans-63.6-0.3-178.400000114.4
181K67.4Low70.4Confident202 Ų202101.2 Ų101.288%0.87852%0.516SS*.THydrogen-bonded Turntrans-118.3-0.6-174.1-71.7-173176.2-179.20114.7S179S179-K181 PolarHBondContact O-N 3.39Å
182V62.8Low70.5Confident72 Ų7298.5 Ų98.544%0.43651%0.51SS..  trans-116.3115.7-176.5-179.90000110.1S179 I184S179-V182 PolarHBondContact O-N 2.84Å; S179-V182 WeakPolarHBondContact OG-CB 3.47Å; S179-V182 WeakPolarHBondContact OG-CG2 3.09Å; V182-I184 HydrophobicContact CG1-CB 4.32Å; V182-I184 WeakPolarHBondContact CG1-O 3.4Å; V182-I184 PolarHBondContact O-N 2.75Å
183N68.1Low71.2Confident169 Ų16994 Ų9490%0.90449%0.489SS*.SBendtrans-70-6.3178.8-78.1-22.5000114.2P185N183-P185 WeakPolarHBondContact O-CD 3.38Å
184I65Low72Confident117 Ų11792.7 Ų92.760%0.648%0.479SS*.  trans-107.2101.8175.3-56.9170.4000107.9V182 F186V182-I184 HydrophobicContact CG1-CB 4.32Å; V182-I184 WeakPolarHBondContact CG1-O 3.4Å; V182-I184 PolarHBondContact O-N 2.75Å; I184-F186 WeakPolarHBondContact CG2-O 3.44Å; I184-F186 PolarHBondContact O-N 2.7Å
185P69.8Low72.7Confident67 Ų6789.5 Ų89.544%0.43546%0.462SS..  trans-67.1-24-172.520-27.6000113.2L176 I177 N183L176-P185 CarbonylContact C-O 3.56Å; L176-P185 VanDerWaalsContact CA-O 3.32Å; L176-P185 WeakPolarHBondContact CA-O 3.21Å; L176-P185 HydrophobicContact CD1-CB 3.71Å; L176-P185 WeakPolarHBondContact CD1-O 3.47Å; I177-P185 PolarHBondContact N-O 2.88Å; N183-P185 WeakPolarHBondContact O-CD 3.38Å
186F73.2Confident73.5Confident99 Ų9984.9 Ų84.943%0.43445%0.448SS..EExtended strand (participates in β ladder)trans-119.6130.7-174.7-62.9-84.5000113.2L174 R175 L176 I184L174-F186 HydrophobicContact CD1-CB 3.62Å; L174-F186 HydrophobicContact CD1-CG 4.45Å; L174-F186 HydrophobicContact CD2-CB 4.02Å; L174-F186 HydrophobicContact CD2-CD1 3.92Å; L174-F186 HydrophobicContact CD2-CG 3.99Å; L174-F186 HydrophobicContact CG-CB 3.72Å; L174-F186 HydrophobicContact CG-CD1 3.88Å; L174-F186 HydrophobicContact CG-CG 4.06Å; R175-F186 CarbonylContact O-C 3.56Å; R175-F186 VanDerWaalsContact O-CA 3.3Å; R175-F186 WeakPolarHBondContact O-CA 3.31Å; L176-F186 HydrophobicContact CB-CD1 3.95Å; L176-F186 HydrophobicContact CB-CE1 3.73Å; L176-F186 HydrophobicContact CD1-CD1 3.98Å; L176-F186 HydrophobicContact CD1-CD2 4.34Å; L176-F186 HydrophobicContact CD1-CE1 3.59Å; L176-F186 HydrophobicContact CD1-CE2 3.95Å; L176-F186 HydrophobicContact CD1-CG 4.34Å; L176-F186 HydrophobicContact CD1-CZ 3.56Å; L176-F186 HydrophobicContact CG-CE1 4.24Å; I184-F186 WeakPolarHBondContact CG2-O 3.44Å; I184-F186 PolarHBondContact O-N 2.7Å
187I72Confident73.8Confident77 Ų7782.9 Ų82.940%0.39545%0.45SS..EExtended strand (participates in β ladder)trans-115.8133.7171.9-55.4-166000109.2R175 I177 T189R175-I187 PolarHBondContact N-O 2.92Å; R175-I187 PolarHBondContact O-N 3.43Å; I177-I187 HydrophobicContact CD1-CB 4.18Å; I177-I187 HydrophobicContact CD1-CD1 3.45Å; I177-I187 VanDerWaalsContact CD1-CD1 3.45Å; I177-I187 HydrophobicContact CD1-CG1 3.84Å; I177-I187 HydrophobicContact CG1-CD1 4.38Å; I177-I187 HydrophobicContact CG1-CG1 4.29Å; I187-T189 PolarHBondContact O-N 2.83Å
188W67Low74.3Confident173 Ų17382 Ų8266%0.65546%0.46SS*.EExtended strand (participates in β ladder)trans-68.9116167.8-69.7101.2000109.8K172 L174K172-W188 HydrophobicContact CB-CE3 4.14Å; K172-W188 HydrophobicContact CB-CZ3 4.44Å; L174-W188 HydrophobicContact CB-CD2 4.47Å; L174-W188 HydrophobicContact CB-CE3 4.09Å; L174-W188 HydrophobicContact CB-CH2 4.23Å; L174-W188 HydrophobicContact CB-CZ3 3.97Å; L174-W188 HydrophobicContact CD1-CD2 3.75Å; L174-W188 HydrophobicContact CD1-CE3 4.23Å; L174-W188 HydrophobicContact CD1-CG 4.08Å; L174-W188 HydrophobicContact CD1-CH2 4.45Å; L174-W188 HydrophobicContact CD1-CZ2 3.99Å
189T66.2Low75.2Confident33 Ų3377.6 Ų77.620%0.20245%0.454CS..EExtended strand (participates in β ladder)trans-104.1138.117263.70000109.5T173 R175 I187T173-T189 PolarHBondContact N-O 2.9Å; T173-T189 PolarHBondContact O-N 2.84Å; T173-T189 PolarHBondContact O-OG1 3.34Å; T173-T189 VanDerWaalsContact O-OG1 3.11Å; R175-T189 HydrophobicContact CB-CG2 4.07Å; R175-T189 HydrophobicContact CG-CG2 4.05Å; I187-T189 PolarHBondContact O-N 2.83Å
190Q67.7Low76.6Confident85 Ų8579.1 Ų79.140%0.39746%0.458SS..EExtended strand (participates in β ladder)trans-104118.4174-71.4-17917.700108.4V170 K171 K172V170-Q190 HydrophobicContact CG1-CB 3.95Å; V170-Q190 HydrophobicContact CG1-CG 4.44Å; K171-Q190 WeakPolarHBondContact O-CA 3.49Å; K172-Q190 HydrophobicContact CG-CG 3.78Å
191N76.2Confident77.9Confident51 Ų5175.4 Ų75.427%0.27342%0.422SS..EExtended strand (participates in β ladder)trans-121.7132.1177.7-59.5-42.6000108.8K171 R175K171-N191 PolarHBondContact N-O 3.32Å; K171-N191 PolarHBondContact O-N 3.15Å; K171-N191 VanDerWaalsContact O-N 3.1Å; R175-N191 PolarHBondContact NH2-ND2 3.12Å
192G83.2Confident79.1Confident22 Ų2267 Ų6723%0.22739%0.385CS..EExtended strand (participates in β ladder)trans-60.5137.2167.200000111.2
193R90.4Very high80.5Confident53 Ų5371.1 Ų71.120%0.239%0.393CS..EExtended strand (participates in β ladder)trans-132149.6174-58.6-68.4-163124.50.4109.5F168 V169 K171 D201 F202F168-R193 CarbonylContact C-O 3.59Å; F168-R193 WeakPolarHBondContact CA-O 3.31Å; F168-R193 WeakPolarHBondContact CD2-O 3.18Å; V169-R193 PolarHBondContact N-O 3.01Å; V169-R193 PolarHBondContact O-N 2.89Å; K171-R193 HydrophobicContact CB-CG 4.3Å; K171-R193 HydrophobicContact CD-CG 4.1Å; K171-R193 HydrophobicContact CG-CG 4.08Å; R193-D201 HydrophobicContact CB-CB 4.1Å; R193-D201 WeakPolarHBondContact CB-OD1 3.26Å; R193-D201 WeakPolarHBondContact CD-OD1 3.33Å; R193-D201 WeakPolarHBondContact CG-OD1 3.43Å; R193-D201 IonicContact CZ-OD1 3.73Å; R193-D201 VanDerWaalsContact CZ-OD1 3.24Å; R193-D201 IonicContact NE-OD1 3.24Å; R193-D201 PolarHBondContact NE-OD1 2.82Å; R193-D201 IonicContact NH1-OD1 2.73Å; R193-D201 PolarHBondContact NH1-OD1 3.4Å; R193-F202 CarbonylContact C-O 3.55Å; R193-F202 WeakPolarHBondContact CA-O 3.36Å
194Y93.4Very high81.6Confident20 Ų2065.7 Ų65.78%0.07837%0.366CS..EExtended strand (participates in β ladder)trans-111131.7177.2-59.9-89.8000109.5Y151 V166 R167 F168 D201 F202 R203 L205Y151-Y194 HydrophobicContact CD2-CD1 4.19Å; Y151-Y194 AromaticContact CD2-CE1 3.88Å; Y151-Y194 HydrophobicContact CD2-CE1 3.88Å; Y151-Y194 HydrophobicContact CE2-CD1 4.31Å; Y151-Y194 AromaticContact CE2-CE1 3.56Å; Y151-Y194 HydrophobicContact CE2-CE1 3.56Å; V166-Y194 HydrophobicContact CG1-CD1 4.28Å; R167-Y194 WeakPolarHBondContact O-CA 3.29Å; F168-Y194 HydrophobicContact CB-CD1 4.43Å; F168-Y194 HydrophobicContact CB-CE1 4.39Å; F168-Y194 AromaticContact CD2-CD1 3.69Å; F168-Y194 HydrophobicContact CD2-CD1 3.69Å; F168-Y194 HydrophobicContact CD2-CD2 4.32Å; F168-Y194 AromaticContact CD2-CE1 3.33Å; F168-Y194 HydrophobicContact CD2-CE1 3.33Å; F168-Y194 AromaticContact CD2-CE2 3.99Å; F168-Y194 HydrophobicContact CD2-CE2 3.99Å; F168-Y194 HydrophobicContact CD2-CG 4.18Å; F168-Y194 AromaticContact CD2-CZ 3.49Å; F168-Y194 VanDerWaalsContact CD2-CZ 3.49Å; F168-Y194 HydrophobicContact CE2-CD2 4.48Å; F168-Y194 AromaticContact CE2-CE1 3.99Å; F168-Y194 HydrophobicContact CE2-CE1 3.99Å; F168-Y194 AromaticContact CE2-CE2 3.9Å; F168-Y194 HydrophobicContact CE2-CE2 3.9Å; F168-Y194 AromaticContact CE2-CZ 3.62Å; F168-Y194 HydrophobicContact CG-CE1 4.22Å; Y194-D201 CarbonylContact O-C 3.58Å; Y194-D201 WeakPolarHBondContact O-CA 3.24Å; Y194-F202 PolarHBondContact N-O 3.45Å; Y194-F202 PolarHBondContact O-N 2.76Å; Y194-R203 WeakPolarHBondContact CE2-O 3.47Å; Y194-L205 HydrophobicContact CD1-CD2 3.27Å; Y194-L205 HydrophobicContact CD1-CG 3.71Å; Y194-L205 HydrophobicContact CE1-CD1 4.15Å; Y194-L205 HydrophobicContact CE1-CD2 3.57Å; Y194-L205 HydrophobicContact CE1-CG 3.51Å; Y194-L205 HydrophobicContact CE2-CG 4.4Å; Y194-L205 HydrophobicContact CG-CD2 3.86Å; Y194-L205 HydrophobicContact CG-CG 4.21Å
195D92.9Very high82.9Confident13 Ų1360.1 Ų60.17%0.0734%0.338CS..EExtended strand (participates in β ladder)trans-141.8156.5177.17885.4000112.2V166 R167 V169 G197 D200 D201V166-D195 CarbonylContact C-O 3.59Å; V166-D195 WeakPolarHBondContact CA-O 3.43Å; R167-D195 IonicContact CZ-OD1 3.41Å; R167-D195 VanDerWaalsContact CZ-OD1 3.32Å; R167-D195 PolarHBondContact N-O 3.41Å; R167-D195 IonicContact NE-OD1 3.7Å; R167-D195 PolarHBondContact NE-OD1 3.33Å; R167-D195 IonicContact NE-OD2 2.72Å; R167-D195 IonicContact NH2-OD1 3.08Å; R167-D195 PolarHBondContact NH2-OD1 3.26Å; R167-D195 PolarHBondContact O-N 2.96Å; V169-D195 VanDerWaalsContact CG2-OD2 3.24Å; V169-D195 WeakPolarHBondContact CG2-OD2 3.31Å; D195-G197 PolarHBondContact OD1-N 3.17Å; D195-D200 WeakPolarHBondContact CB-O 3.33Å; D195-D201 HydrophobicContact CB-CB 4.29Å
196V90.8Very high84.1Confident30 Ų3058.2 Ų58.218%0.18233%0.326CS..  trans-109.813.5173.3-60.20000112.1V164 V166 L208 Y212 M217V164-V196 HydrophobicContact CG1-CB 4.05Å; V164-V196 HydrophobicContact CG1-CG1 3.99Å; V166-V196 HydrophobicContact CG2-CG1 3.93Å; V196-L208 HydrophobicContact CG1-CD1 4.26Å; V196-L208 HydrophobicContact CG1-CD2 4.44Å; V196-Y212 HydrophobicContact CG1-CE2 4.16Å; V196-Y212 HydrophobicContact CG2-CE1 4.26Å; V196-Y212 HydrophobicContact CG2-CE2 3.63Å; V196-Y212 WeakPolarHBondContact CG2-OH 3.41Å; V196-M217 HydrophobicContact CG1-SD 4.39Å; V196-M217 HydrophobicContact CG2-SD 4.19Å
197G85.2Confident85.1Confident49 Ų4957.3 Ų57.351%0.50532%0.323SS..SBendtrans86.54-178.300000117D195D195-G197 PolarHBondContact OD1-N 3.17Å
198G79.2Confident86.3Confident60 Ų6053.7 Ų53.762%0.61930%0.304SS*.SBendtrans-87.83.2-177.800000116.7
199G83Confident87.6Confident70 Ų7045.5 Ų45.572%0.72227%0.274SS*.SBendtrans99.7-33.2-175.800000114
200D90.5Very high88.9Confident81 Ų8147.7 Ų47.743%0.43328%0.284SS..  trans-77141.9173.5-65.1-42.8000112.2D195 F202 H211D195-D200 WeakPolarHBondContact CB-O 3.33Å; D200-F202 HydrophobicContact CB-CE2 3.99Å; D200-F202 HydrophobicContact CB-CZ 3.88Å; D200-H211 IonicContact OD2-CE1 3.99Å
201D91.8Very high90.2Very high41 Ų4146.3 Ų46.322%0.21928%0.277CS..  trans-136144.8173.876.787.6000112.2K171 R193 Y194 D195K171-D201 VanDerWaalsContact NZ-CG 3.32Å; K171-D201 IonicContact NZ-OD1 2.64Å; K171-D201 IonicContact NZ-OD2 3.5Å; K171-D201 PolarHBondContact NZ-OD2 2.75Å; R193-D201 HydrophobicContact CB-CB 4.1Å; R193-D201 WeakPolarHBondContact CB-OD1 3.26Å; R193-D201 WeakPolarHBondContact CD-OD1 3.33Å; R193-D201 WeakPolarHBondContact CG-OD1 3.43Å; R193-D201 IonicContact CZ-OD1 3.73Å; R193-D201 VanDerWaalsContact CZ-OD1 3.24Å; R193-D201 IonicContact NE-OD1 3.24Å; R193-D201 PolarHBondContact NE-OD1 2.82Å; R193-D201 IonicContact NH1-OD1 2.73Å; R193-D201 PolarHBondContact NH1-OD1 3.4Å; Y194-D201 CarbonylContact O-C 3.58Å; Y194-D201 WeakPolarHBondContact O-CA 3.24Å; D195-D201 HydrophobicContact CB-CB 4.29Å
202F93.7Very high91.1Very high24 Ų2444.5 Ų44.511%0.10527%0.267CS..BIsolated β-bridgetrans-123.1154.8-170.4-56.3-83.7000111.5R193 Y194 D200 E207 L208 H211 Y212R193-F202 CarbonylContact C-O 3.55Å; R193-F202 WeakPolarHBondContact CA-O 3.36Å; Y194-F202 PolarHBondContact N-O 3.45Å; Y194-F202 PolarHBondContact O-N 2.76Å; D200-F202 HydrophobicContact CB-CE2 3.99Å; D200-F202 HydrophobicContact CB-CZ 3.88Å; F202-E207 HydrophobicContact CB-CB 3.99Å; F202-E207 HydrophobicContact CD1-CB 4.1Å; F202-E207 HydrophobicContact CG-CB 4.42Å; F202-L208 HydrophobicContact CB-CB 3.94Å; F202-L208 HydrophobicContact CD2-CB 3.57Å; F202-L208 HydrophobicContact CD2-CD1 3.9Å; F202-L208 HydrophobicContact CD2-CG 3.7Å; F202-L208 HydrophobicContact CE2-CB 4.29Å; F202-L208 HydrophobicContact CE2-CG 4.11Å; F202-L208 HydrophobicContact CG-CB 3.78Å; F202-L208 HydrophobicContact CG-CG 4.42Å; F202-H211 HydrophobicContact CD1-CB 4.33Å; F202-H211 HydrophobicContact CE1-CB 3.41Å; F202-H211 VanDerWaalsContact CE1-CB 3.41Å; F202-H211 AromaticContact CE1-CD2 3.95Å; F202-H211 AromaticContact CE1-CG 3.56Å; F202-H211 HydrophobicContact CZ-CB 3.54Å; F202-H211 AromaticContact CZ-CD2 3.94Å; F202-H211 AromaticContact CZ-CG 3.35Å; F202-H211 AromaticContact CZ-ND1 3.46Å; F202-H211 WeakPolarHBondContact CZ-ND1 3.4Å; F202-Y212 AromaticContact CE2-CE2 3.83Å; F202-Y212 HydrophobicContact CE2-CE2 3.83Å; F202-Y212 HydrophobicContact CZ-CE2 4.37Å
203R90.5Very high91.6Very high160 Ų16048.5 Ų48.560%0.60428%0.275SS*.SBendtrans-80.7-28.8-179.8-58.7177.9-176176.34.9112.4Y194 E207Y194-R203 WeakPolarHBondContact CE2-O 3.47Å; R203-E207 WeakPolarHBondContact CB-OE2 3.36Å; R203-E207 PolarHBondContact N-OE2 3.48Å
204T91.7Very high91.7Very high54 Ų5454.4 Ų54.433%0.33130%0.302SS..SBendtrans-132.8155.5-179.568.30000110.5S206 E207 L208T204-S206 PolarHBondContact O-N 3.46Å; T204-E207 PolarHBondContact O-N 3.01Å; T204-E207 WeakPolarHBondContact OG1-CG 3.49Å; T204-E207 PolarHBondContact OG1-N 3.29Å; T204-L208 PolarHBondContact O-N 3.48Å
205L93.5Very high91.6Very high1 Ų156.3 Ų56.31%0.00532%0.319CS..Hα-helixtrans-59.6-31.8170.8-70.9172.1000111.5P111 W116 V141 Y151 V166 Y194 L208 V209P111-L205 HydrophobicContact CB-CD1 3.93Å; P111-L205 HydrophobicContact CG-CD1 3.58Å; W116-L205 HydrophobicContact CH2-CB 3.7Å; W116-L205 HydrophobicContact CZ3-CB 4.27Å; V141-L205 HydrophobicContact CG1-CD1 4.39Å; Y151-L205 HydrophobicContact CD1-CD1 4.13Å; Y151-L205 HydrophobicContact CD2-CD1 4.41Å; Y151-L205 HydrophobicContact CD2-CD2 4.26Å; Y151-L205 HydrophobicContact CE1-CD1 4.19Å; Y151-L205 HydrophobicContact CE2-CD1 4.49Å; Y151-L205 HydrophobicContact CG-CD1 4.23Å; Y151-L205 HydrophobicContact CG-CD2 4.33Å; V166-L205 HydrophobicContact CG1-CD2 3.78Å; Y194-L205 HydrophobicContact CD1-CD2 3.27Å; Y194-L205 HydrophobicContact CD1-CG 3.71Å; Y194-L205 HydrophobicContact CE1-CD1 4.15Å; Y194-L205 HydrophobicContact CE1-CD2 3.57Å; Y194-L205 HydrophobicContact CE1-CG 3.51Å; Y194-L205 HydrophobicContact CE2-CG 4.4Å; Y194-L205 HydrophobicContact CG-CD2 3.86Å; Y194-L205 HydrophobicContact CG-CG 4.21Å; L205-L208 PolarHBondContact O-N 2.88Å; L205-V209 WeakPolarHBondContact O-CB 3.34Å; L205-V209 WeakPolarHBondContact O-CG2 3.34Å; L205-V209 PolarHBondContact O-N 3.48Å
206S93.8Very high91.4Very high26 Ų2658 Ų5818%0.18233%0.33CS..Hα-helixtrans-63.9-46.8176.8-58.10000112.1T112 E114 T204 L208 V209 D210T112-S206 PolarHBondContact OG1-OG 3.14Å; E114-S206 WeakPolarHBondContact CG-OG 3.36Å; T204-S206 PolarHBondContact O-N 3.46Å; S206-L208 VanDerWaalsContact C-N 3.31Å; S206-L208 PolarHBondContact O-N 2.71Å; S206-V209 PolarHBondContact O-N 3.4Å; S206-D210 WeakPolarHBondContact O-CB 3.24Å; S206-D210 VanDerWaalsContact O-CG 3.29Å; S206-D210 PolarHBondContact O-N 3.09Å
207E95.3Very high91.3Very high80 Ų8057.5 Ų57.537%0.37433%0.326SS..Hα-helixtrans-59.3-42.2174.4-75.3172.4-167.600111.8F202 R203 T204 D210 H211F202-E207 HydrophobicContact CB-CB 3.99Å; F202-E207 HydrophobicContact CD1-CB 4.1Å; F202-E207 HydrophobicContact CG-CB 4.42Å; R203-E207 WeakPolarHBondContact CB-OE2 3.36Å; R203-E207 PolarHBondContact N-OE2 3.48Å; T204-E207 PolarHBondContact O-N 3.01Å; T204-E207 WeakPolarHBondContact OG1-CG 3.49Å; T204-E207 PolarHBondContact OG1-N 3.29Å; E207-D210 PolarHBondContact O-N 3.44Å; E207-H211 WeakPolarHBondContact O-CB 3.22Å; E207-H211 PolarHBondContact O-N 3.09Å
208L95.5Very high91.4Very high2 Ų259.9 Ų59.91%0.0133%0.33CS..Hα-helixtrans-60.9-49.8176.8-177.8153.4000111.3V166 V196 F202 T204 L205 S206 H211 Y212V166-L208 HydrophobicContact CG1-CD1 3.69Å; V166-L208 HydrophobicContact CG2-CD2 4.46Å; V196-L208 HydrophobicContact CG1-CD1 4.26Å; V196-L208 HydrophobicContact CG1-CD2 4.44Å; F202-L208 HydrophobicContact CB-CB 3.94Å; F202-L208 HydrophobicContact CD2-CB 3.57Å; F202-L208 HydrophobicContact CD2-CD1 3.9Å; F202-L208 HydrophobicContact CD2-CG 3.7Å; F202-L208 HydrophobicContact CE2-CB 4.29Å; F202-L208 HydrophobicContact CE2-CG 4.11Å; F202-L208 HydrophobicContact CG-CB 3.78Å; F202-L208 HydrophobicContact CG-CG 4.42Å; T204-L208 PolarHBondContact O-N 3.48Å; L205-L208 PolarHBondContact O-N 2.88Å; S206-L208 VanDerWaalsContact C-N 3.31Å; S206-L208 PolarHBondContact O-N 2.71Å; L208-H211 PolarHBondContact O-N 3.11Å; L208-Y212 HydrophobicContact CD2-CD2 3.8Å; L208-Y212 HydrophobicContact CD2-CE2 4.23Å; L208-Y212 HydrophobicContact CG-CD2 3.94Å; L208-Y212 HydrophobicContact CG-CE2 3.99Å; L208-Y212 WeakPolarHBondContact O-CD2 3.25Å; L208-Y212 PolarHBondContact O-N 3.28Å
209V95.1Very high91.5Very high1 Ų159.1 Ų59.11%0.00631%0.311CS..Hα-helixtrans-62.3-47.9179.2168.30000110W116 F139 V141 L205 S206 H211 Y212 R213W116-V209 HydrophobicContact CD2-CG2 4.47Å; W116-V209 HydrophobicContact CE3-CG2 4.27Å; W116-V209 HydrophobicContact CH2-CB 4.44Å; W116-V209 HydrophobicContact CH2-CG2 3.77Å; W116-V209 HydrophobicContact CZ2-CB 4.16Å; W116-V209 HydrophobicContact CZ2-CG1 4.48Å; W116-V209 HydrophobicContact CZ2-CG2 3.94Å; W116-V209 HydrophobicContact CZ3-CG2 3.95Å; F139-V209 HydrophobicContact CE2-CG1 3.66Å; F139-V209 HydrophobicContact CZ-CG1 3.79Å; V141-V209 HydrophobicContact CG2-CG2 4.06Å; L205-V209 WeakPolarHBondContact O-CB 3.34Å; L205-V209 WeakPolarHBondContact O-CG2 3.34Å; L205-V209 PolarHBondContact O-N 3.48Å; S206-V209 PolarHBondContact O-N 3.4Å; V209-H211 VanDerWaalsContact C-N 3.29Å; V209-H211 PolarHBondContact O-N 2.94Å; V209-Y212 CarbonylContact O-C 3.45Å; V209-Y212 PolarHBondContact O-N 3.33Å; V209-Y212 VanDerWaalsContact O-N 3.15Å; V209-R213 HydrophobicContact CG1-CG 4.11Å; V209-R213 WeakPolarHBondContact O-CB 3.42Å; V209-R213 WeakPolarHBondContact O-CG 3.33Å; V209-R213 PolarHBondContact O-N 3.25Å
210D94.4Very high91.5Very high78 Ų7863.5 Ų63.542%0.41732%0.324SS..Hα-helixtrans-61.6-36.2-179.6-73.9-20.8000112.9S206 E207 K214S206-D210 WeakPolarHBondContact O-CB 3.24Å; S206-D210 VanDerWaalsContact O-CG 3.29Å; S206-D210 PolarHBondContact O-N 3.09Å; E207-D210 PolarHBondContact O-N 3.44Å; D210-K214 WeakPolarHBondContact O-CG 3.42Å; D210-K214 PolarHBondContact O-N 3Å
211H94.3Very high91.2Very high56 Ų5663.6 Ų63.626%0.25933%0.331SS..Hα-helixtrans-61.5-54.8171.3178.5-94.5000111.1D200 F202 E207 L208 V209 R213 K214 S215D200-H211 IonicContact OD2-CE1 3.99Å; F202-H211 HydrophobicContact CD1-CB 4.33Å; F202-H211 HydrophobicContact CE1-CB 3.41Å; F202-H211 VanDerWaalsContact CE1-CB 3.41Å; F202-H211 AromaticContact CE1-CD2 3.95Å; F202-H211 AromaticContact CE1-CG 3.56Å; F202-H211 HydrophobicContact CZ-CB 3.54Å; F202-H211 AromaticContact CZ-CD2 3.94Å; F202-H211 AromaticContact CZ-CG 3.35Å; F202-H211 AromaticContact CZ-ND1 3.46Å; F202-H211 WeakPolarHBondContact CZ-ND1 3.4Å; E207-H211 WeakPolarHBondContact O-CB 3.22Å; E207-H211 PolarHBondContact O-N 3.09Å; L208-H211 PolarHBondContact O-N 3.11Å; V209-H211 VanDerWaalsContact C-N 3.29Å; V209-H211 PolarHBondContact O-N 2.94Å; H211-R213 VanDerWaalsContact C-N 3.25Å; H211-R213 PolarHBondContact O-N 3.49Å; H211-K214 PolarHBondContact O-N 2.93Å; H211-S215 PolarHBondContact O-N 2.9Å
212Y94.2Very high90.8Very high14 Ų1464 Ų646%0.05534%0.344CS..Hα-helixtrans-73.9-12.5-176.4-71.9-62.5000114.6V196 F202 L208 V209 S215 M217V196-Y212 HydrophobicContact CG1-CE2 4.16Å; V196-Y212 HydrophobicContact CG2-CE1 4.26Å; V196-Y212 HydrophobicContact CG2-CE2 3.63Å; V196-Y212 WeakPolarHBondContact CG2-OH 3.41Å; F202-Y212 AromaticContact CE2-CE2 3.83Å; F202-Y212 HydrophobicContact CE2-CE2 3.83Å; F202-Y212 HydrophobicContact CZ-CE2 4.37Å; L208-Y212 HydrophobicContact CD2-CD2 3.8Å; L208-Y212 HydrophobicContact CD2-CE2 4.23Å; L208-Y212 HydrophobicContact CG-CD2 3.94Å; L208-Y212 HydrophobicContact CG-CE2 3.99Å; L208-Y212 WeakPolarHBondContact O-CD2 3.25Å; L208-Y212 PolarHBondContact O-N 3.28Å; V209-Y212 CarbonylContact O-C 3.45Å; V209-Y212 PolarHBondContact O-N 3.33Å; V209-Y212 VanDerWaalsContact O-N 3.15Å; Y212-S215 WeakPolarHBondContact CA-O 3.37Å; Y212-S215 VanDerWaalsContact CD1-O 3.31Å; Y212-S215 WeakPolarHBondContact CD1-O 3.26Å; Y212-M217 HydrophobicContact CD1-CB 4.47Å; Y212-M217 HydrophobicContact CD1-CG 3.19Å; Y212-M217 HydrophobicContact CD1-SD 4.04Å; Y212-M217 HydrophobicContact CD2-SD 4.42Å; Y212-M217 HydrophobicContact CE1-CG 3.4Å; Y212-M217 VanDerWaalsContact CE1-CG 3.4Å; Y212-M217 HydrophobicContact CE1-SD 4.23Å; Y212-M217 HydrophobicContact CG-CE 4.46Å; Y212-M217 HydrophobicContact CG-CG 3.86Å; Y212-M217 HydrophobicContact CG-SD 4.15Å
213R93.9Very high90.5Very high105 Ų10565.2 Ų65.240%0.39635%0.354SS..Hα-helixtrans-71-33.9164.9-72.7-178.278.91724.4112.3F139 V209 H211 L227F139-R213 HydrophobicContact CZ-CG 4.45Å; V209-R213 HydrophobicContact CG1-CG 4.11Å; V209-R213 WeakPolarHBondContact O-CB 3.42Å; V209-R213 WeakPolarHBondContact O-CG 3.33Å; V209-R213 PolarHBondContact O-N 3.25Å; H211-R213 VanDerWaalsContact C-N 3.25Å; H211-R213 PolarHBondContact O-N 3.49Å; R213-L227 HydrophobicContact CG-CB 3.73Å; R213-L227 HydrophobicContact CG-CD1 4.47Å; R213-L227 WeakPolarHBondContact CG-O 3.25Å
214K93.5Very high90.4Very high177 Ų17760.6 Ų60.677%0.7734%0.344SS*.Hα-helixtrans-90.2-36.1179.7-65.5172.3-174.9172.50112.4D210 H211D210-K214 WeakPolarHBondContact O-CG 3.42Å; D210-K214 PolarHBondContact O-N 3Å; H211-K214 PolarHBondContact O-N 2.93Å
215S91.5Very high90.3Very high61 Ų6158.1 Ų58.143%0.42733%0.328SS..SBendtrans-122.287.7-177.8-60.10000109.5H211 Y212H211-S215 PolarHBondContact O-N 2.9Å; Y212-S215 WeakPolarHBondContact CA-O 3.37Å; Y212-S215 VanDerWaalsContact CD1-O 3.31Å; Y212-S215 WeakPolarHBondContact CD1-O 3.26Å
216P88Confident90.2Very high49 Ų4961.8 Ų61.832%0.31835%0.345SS..  trans-58.8145.7-174.6-2635.9000113.8V224 H226P216-V224 HydrophobicContact CB-CG1 3.48Å; P216-V224 VanDerWaalsContact CB-CG1 3.48Å; P216-V224 HydrophobicContact CG-CG1 4.35Å; P216-H226 WeakPolarHBondContact CG-ND1 3.2Å
217M88.7Confident90.3Very high19 Ų1960.8 Ų60.89%0.09434%0.338CS..EExtended strand (participates in β ladder)trans-75.4157.6174.3-60.3169.6-76.900110.8L153 V164 V196 Y212 V224 V225 L227L153-M217 HydrophobicContact CD2-CE 3.54Å; V164-M217 HydrophobicContact CG1-SD 3.96Å; V164-M217 HydrophobicContact CG2-CE 4.2Å; V164-M217 HydrophobicContact CG2-SD 4.38Å; V196-M217 HydrophobicContact CG1-SD 4.39Å; V196-M217 HydrophobicContact CG2-SD 4.19Å; Y212-M217 HydrophobicContact CD1-CB 4.47Å; Y212-M217 HydrophobicContact CD1-CG 3.19Å; Y212-M217 HydrophobicContact CD1-SD 4.04Å; Y212-M217 HydrophobicContact CD2-SD 4.42Å; Y212-M217 HydrophobicContact CE1-CG 3.4Å; Y212-M217 VanDerWaalsContact CE1-CG 3.4Å; Y212-M217 HydrophobicContact CE1-SD 4.23Å; Y212-M217 HydrophobicContact CG-CE 4.46Å; Y212-M217 HydrophobicContact CG-CG 3.86Å; Y212-M217 HydrophobicContact CG-SD 4.15Å; M217-V224 CarbonylContact O-C 3.58Å; M217-V224 WeakPolarHBondContact O-CA 3.47Å; M217-V225 HydrophobicContact CB-CB 4.23Å; M217-V225 HydrophobicContact CB-CG2 4.49Å; M217-V225 HydrophobicContact CE-CB 4.39Å; M217-V225 HydrophobicContact CE-CG1 4.09Å; M217-V225 PolarHBondContact N-O 2.99Å; M217-V225 PolarHBondContact O-N 2.76Å; M217-L227 HydrophobicContact CE-CD2 4.36Å
218V86.9Confident90.1Very high98 Ų9861.9 Ų61.959%0.59434%0.341SS*.EExtended strand (participates in β ladder)trans-123124.1175-172.80000108.8V224V218-V224 HydrophobicContact CG2-CG2 4.36Å
219E82.6Confident90.1Very high45 Ų4565.1 Ų65.121%0.2136%0.355CS..  trans-65.9160.2172.6-71.9175.2-165.800111Q157 R160 T162 S221 G222 T223 V225Q157-E219 PolarHBondContact NE2-OE1 3.32Å; Q157-E219 VanDerWaalsContact NE2-OE1 3.11Å; Q157-E219 PolarHBondContact OE1-OE1 3.32Å; R160-E219 IonicContact NH2-OE1 2.85Å; R160-E219 IonicContact NH2-OE2 3.52Å; R160-E219 PolarHBondContact NH2-OE2 2.98Å; T162-E219 VanDerWaalsContact CG2-OE1 3.3Å; T162-E219 WeakPolarHBondContact CG2-OE1 3.48Å; T162-E219 PolarHBondContact OG1-OE1 3.14Å; E219-S221 WeakPolarHBondContact CB-OG 3.43Å; E219-S221 PolarHBondContact O-N 2.92Å; E219-S221 PolarHBondContact OE2-OG 3.42Å; E219-S221 VanDerWaalsContact OE2-OG 3.13Å; E219-G222 WeakPolarHBondContact O-CA 3.13Å; E219-G222 PolarHBondContact O-N 3.48Å; E219-T223 PolarHBondContact N-O 3.25Å; E219-V225 HydrophobicContact CG-CG2 3.8Å
220T81.8Confident90Very high162 Ų16267 Ų6799%0.99437%0.368SS*.THydrogen-bonded Turntrans-57.5-24.2173.4-18.30000113G222T220-G222 PolarHBondContact O-N 2.88Å
221S84.2Confident90Very high82 Ų8264.3 Ų64.357%0.57335%0.353SS*.THydrogen-bonded Turntrans-72.1-10173.665.90000113.8E219 T223E219-S221 WeakPolarHBondContact CB-OG 3.43Å; E219-S221 PolarHBondContact O-N 2.92Å; E219-S221 PolarHBondContact OE2-OG 3.42Å; E219-S221 VanDerWaalsContact OE2-OG 3.13Å; S221-T223 VanDerWaalsContact C-N 3.34Å; S221-T223 WeakPolarHBondContact OG-CB 3.21Å; S221-T223 PolarHBondContact OG-N 2.73Å; S221-T223 PolarHBondContact OG-OG1 2.8Å
222G84.6Confident89.9Confident49 Ų4963.7 Ų63.751%0.50535%0.352SS..SBendtrans85.8-1.4-169.200000114.2E219 T220 V224E219-G222 WeakPolarHBondContact O-CA 3.13Å; E219-G222 PolarHBondContact O-N 3.48Å; T220-G222 PolarHBondContact O-N 2.88Å; G222-V224 PolarHBondContact O-N 2.92Å
223T86.5Confident89.7Confident51 Ų5163.6 Ų63.631%0.31335%0.353SS..  trans-72.4126.1-179.8-54.30000111.1E219 S221E219-T223 PolarHBondContact N-O 3.25Å; S221-T223 VanDerWaalsContact C-N 3.34Å; S221-T223 WeakPolarHBondContact OG-CB 3.21Å; S221-T223 PolarHBondContact OG-N 2.73Å; S221-T223 PolarHBondContact OG-OG1 2.8Å
224V88.6Confident89.5Confident63 Ų6359 Ų5938%0.38234%0.337SS..EExtended strand (participates in β ladder)trans-80.9124.5178-172.50000110.9P216 M217 V218 G222 H226P216-V224 HydrophobicContact CB-CG1 3.48Å; P216-V224 VanDerWaalsContact CB-CG1 3.48Å; P216-V224 HydrophobicContact CG-CG1 4.35Å; M217-V224 CarbonylContact O-C 3.58Å; M217-V224 WeakPolarHBondContact O-CA 3.47Å; V218-V224 HydrophobicContact CG2-CG2 4.36Å; G222-V224 PolarHBondContact O-N 2.92Å; V224-H226 WeakPolarHBondContact CG1-NE2 3.4Å
225V90.3Very high89.3Confident2 Ų254.3 Ų54.31%0.01232%0.316CS..EExtended strand (participates in β ladder)trans-94.7103.4179.2-172.70000109.1V155 Q157 M217 E219V155-V225 HydrophobicContact CB-CG1 3.89Å; V155-V225 HydrophobicContact CG1-CG1 3.84Å; V155-V225 HydrophobicContact CG2-CG1 3.78Å; Q157-V225 VanDerWaalsContact NE2-CG2 3.31Å; M217-V225 HydrophobicContact CB-CB 4.23Å; M217-V225 HydrophobicContact CB-CG2 4.49Å; M217-V225 HydrophobicContact CE-CB 4.39Å; M217-V225 HydrophobicContact CE-CG1 4.09Å; M217-V225 PolarHBondContact N-O 2.99Å; M217-V225 PolarHBondContact O-N 2.76Å; E219-V225 HydrophobicContact CG-CG2 3.8Å
226H91.6Very high89.1Confident77 Ų7751.6 Ų51.636%0.35630%0.297SS..  trans-94.1123.8-180-64.5-83.2000112.8P216 V224 K228P216-H226 WeakPolarHBondContact CG-ND1 3.2Å; V224-H226 WeakPolarHBondContact CG1-NE2 3.4Å; H226-K228 HydrophobicContact CB-CD 4.27Å; H226-K228 HydrophobicContact CB-CG 3.86Å; H226-K228 PolarHBondContact O-N 2.97Å
227L93.9Very high88.8Confident6 Ų649.6 Ų49.63%0.03128%0.283CS..  trans-89.785.1170.2-52.5-172.9000110F139 L153 V155 R213 M217F139-L227 HydrophobicContact CB-CD2 3.91Å; F139-L227 HydrophobicContact CD1-CB 3.82Å; F139-L227 HydrophobicContact CD1-CD2 4.34Å; F139-L227 HydrophobicContact CE1-CB 3.95Å; F139-L227 HydrophobicContact CG-CB 4.28Å; F139-L227 HydrophobicContact CG-CD2 4.03Å; L153-L227 HydrophobicContact CD1-CD1 4.38Å; L153-L227 HydrophobicContact CD1-CD2 4.08Å; L153-L227 HydrophobicContact CD2-CD1 3.81Å; L153-L227 HydrophobicContact CD2-CD2 3.99Å; L153-L227 HydrophobicContact CD2-CG 4.5Å; L153-L227 HydrophobicContact CG-CD2 4.27Å; V155-L227 HydrophobicContact CB-CD2 4.41Å; V155-L227 HydrophobicContact CG1-CD2 4.08Å; V155-L227 HydrophobicContact CG2-CD2 3.41Å; V155-L227 VanDerWaalsContact CG2-CD2 3.41Å; R213-L227 HydrophobicContact CG-CB 3.73Å; R213-L227 HydrophobicContact CG-CD1 4.47Å; R213-L227 WeakPolarHBondContact CG-O 3.25Å; M217-L227 HydrophobicContact CE-CD2 4.36Å
228K93Very high88.7Confident102 Ų10248.7 Ų48.744%0.44328%0.279SS..  trans-93.5-51.9-175.1-60-172.9179.3-179.60112G137 H226G137-K228 WeakPolarHBondContact O-CA 3.43Å; G137-K228 PolarHBondContact O-N 3.01Å; H226-K228 HydrophobicContact CB-CD 4.27Å; H226-K228 HydrophobicContact CB-CG 3.86Å; H226-K228 PolarHBondContact O-N 2.97Å
229F93.6Very high88.5Confident70 Ų7047.2 Ų47.231%0.30727%0.27SS..EExtended strand (participates in β ladder)trans-125108-166.8-49.8-64000111.2R135 N136 G137 S138 F139 L231R135-F229 HydrophobicContact CG-CD2 3.61Å; R135-F229 HydrophobicContact CG-CE2 4.03Å; R135-F229 HydrophobicContact CG-CG 4.25Å; R135-F229 VanDerWaalsContact NE-CG 3.29Å; N136-F229 WeakPolarHBondContact O-CE2 3.25Å; G137-F229 PolarHBondContact O-N 2.66Å; S138-F229 CarbonylContact C-O 3.57Å; S138-F229 WeakPolarHBondContact CA-O 3.19Å; F139-F229 WeakPolarHBondContact CD1-O 3.45Å; F139-F229 PolarHBondContact N-O 3.46Å; F229-L231 PolarHBondContact O-N 2.85Å
230P94Very high88.6Confident42 Ų4246.2 Ų46.227%0.27327%0.268SS..EExtended strand (participates in β ladder)trans-62.2126.8173.824.5-31.3000109.7W116 F139 N232W116-P230 HydrophobicContact CB-CB 3.77Å; W116-P230 HydrophobicContact CG-CB 4.31Å; F139-P230 HydrophobicContact CE1-CB 4.06Å; F139-P230 HydrophobicContact CE2-CB 4.3Å; F139-P230 HydrophobicContact CZ-CB 3.76Å; F139-P230 HydrophobicContact CZ-CG 4.47Å; P230-N232 PolarHBondContact O-N 3.3Å
231L93.4Very high89.1Confident20 Ų2038.6 Ų38.611%0.10522%0.222CC..  trans-84.9108167.6-175.765.3000107.6H118 L129 L130 Q133 F139 L140 F229H118-L231 PolarHBondContact NE2-O 2.81Å; L129-L231 HydrophobicContact CB-CD2 4.05Å; L130-L231 HydrophobicContact CD2-CB 4.32Å; L130-L231 HydrophobicContact CD2-CD2 4.05Å; L130-L231 HydrophobicContact CG-CD2 4.38Å; Q133-L231 HydrophobicContact CB-CD1 4.08Å; F139-L231 PolarHBondContact O-N 3.26Å; L140-L231 HydrophobicContact CD2-CD2 4.19Å; F229-L231 PolarHBondContact O-N 2.85Å
232N92.4Very high89.4Confident44 Ų4437.8 Ų37.824%0.23521%0.211CC..  trans-81.3135.6-174.3-69.1-28.4000111.8R115 P230 E260R115-N232 HydrophobicContact CB-CB 3.85Å; R115-N232 WeakPolarHBondContact CB-OD1 3.43Å; R115-N232 PolarHBondContact NH1-ND2 3.09Å; R115-N232 CarbonylContact O-C 3.51Å; R115-N232 WeakPolarHBondContact O-CA 3.44Å; P230-N232 PolarHBondContact O-N 3.3Å; N232-E260 PolarHBondContact ND2-OE1 2.83Å
233T91.1Very high89.6Confident12 Ų1236.1 Ų36.17%0.07419%0.194CC..  trans-90141172.9-166.70000112.1R115 F117 K235 R244R115-T233 PolarHBondContact O-N 3.45Å; F117-T233 VanDerWaalsContact O-CG2 3.23Å; F117-T233 WeakPolarHBondContact O-CG2 3.4Å; T233-K235 PolarHBondContact OG1-N 2.79Å; T233-R244 PolarHBondContact O-NH1 3.34Å
234T88.9Confident89.8Confident9 Ų934.8 Ų34.86%0.05518%0.183CC..  trans-95.6-7.3169.753.30000113.4E261 D559 R561T234-E261 HydrophobicContact CG2-CG 4.25Å; T234-D559 WeakPolarHBondContact CB-OD1 3.42Å; T234-D559 PolarHBondContact OG1-OD1 3.34Å; T234-D559 PolarHBondContact OG1-OD2 3.43Å; T234-R561 HydrophobicContact CG2-CB 3.79Å; T234-R561 HydrophobicContact CG2-CG 4.23Å; T234-R561 VanDerWaalsContact CG2-NE 3.26Å; T234-R561 PolarHBondContact OG1-NE 3.21Å; T234-R561 VanDerWaalsContact OG1-NE 3.13Å; T234-R561 PolarHBondContact OG1-NH2 2.8Å
235K89.9Confident90Very high78 Ų7832.6 Ų32.634%0.33917%0.17SC..EExtended strand (participates in β ladder)trans-72.4138.6173.1-65.7-176.5178.9-176.80110.3T233 R244 T557 D559T233-K235 PolarHBondContact OG1-N 2.79Å; K235-R244 PolarHBondContact O-NH2 3.02Å; K235-T557 HydrophobicContact CB-CG2 3.78Å; K235-T557 HydrophobicContact CD-CG2 4.24Å; K235-T557 HydrophobicContact CG-CG2 4.13Å; K235-D559 HydrophobicContact CG-CB 4.29Å; K235-D559 PolarHBondContact N-OD2 3.41Å
236I87.6Confident90.1Very high4 Ų438.1 Ų38.12%0.02119%0.194CC..EExtended strand (participates in β ladder)trans-137.8137.4-173.4-59.9154.7000109.2I241 R244 I558 Y585I236-I241 HydrophobicContact CG2-CB 4.22Å; I236-I241 HydrophobicContact CG2-CG1 4.35Å; I236-R244 HydrophobicContact CD1-CG 3.83Å; I236-R244 HydrophobicContact CG1-CG 3.95Å; I236-R244 VanDerWaalsContact CG1-CZ 3.47Å; I236-R244 HydrophobicContact CG2-CB 4.46Å; I236-I558 HydrophobicContact CB-CD1 4.5Å; I236-I558 HydrophobicContact CB-CG1 3.93Å; I236-I558 HydrophobicContact CG2-CD1 4.45Å; I236-I558 HydrophobicContact CG2-CG1 4.32Å; I236-I558 PolarHBondContact N-O 2.79Å; I236-I558 WeakPolarHBondContact O-CG1 3.29Å; I236-I558 PolarHBondContact O-N 3.38Å; I236-Y585 HydrophobicContact CD1-CD1 4.35Å; I236-Y585 HydrophobicContact CD1-CE1 3.39Å
237N82.2Confident89.9Confident6 Ų636.9 Ų36.93%0.03219%0.187CC..  trans-77.7127.8160.5-179.4-33000108.5R9 T239 S240 I241 L554R9-N237 PolarHBondContact NH1-ND2 2.78Å; N237-T239 PolarHBondContact ND2-OG1 2.94Å; N237-T239 PolarHBondContact O-N 3.13Å; N237-T239 VanDerWaalsContact O-N 3.12Å; N237-T239 WeakPolarHBondContact OD1-CB 3.32Å; N237-T239 PolarHBondContact OD1-N 2.71Å; N237-T239 PolarHBondContact OD1-OG1 2.97Å; N237-S240 PolarHBondContact O-N 3.37Å; N237-I241 PolarHBondContact O-N 3.44Å; N237-L554 PolarHBondContact OD1-O 3.1Å
238P85.9Confident89.7Confident0 Ų036.8 Ų36.80%019%0.187CC..G310 helixtrans-43.5-45.1173.8-31.836.5000113.8S240 I241 V549 L554 C556 I558 I592P238-S240 PolarHBondContact O-N 2.7Å; P238-I241 WeakPolarHBondContact O-CB 3.46Å; P238-I241 WeakPolarHBondContact O-CG2 3.43Å; P238-I241 PolarHBondContact O-N 3.41Å; P238-I241 VanDerWaalsContact O-N 3.14Å; P238-V549 HydrophobicContact CG-CG2 4.27Å; P238-L554 HydrophobicContact CB-CD2 4.1Å; P238-C556 WeakPolarHBondContact CD-O 3.12Å; P238-I558 HydrophobicContact CG-CG1 4.48Å; P238-I558 HydrophobicContact CG-CG2 4.03Å; P238-I592 HydrophobicContact CB-CD1 3.62Å; P238-I592 HydrophobicContact CB-CG1 4.04Å; P238-I592 HydrophobicContact CB-CG2 4.26Å; P238-I592 HydrophobicContact CG-CD1 4.5Å; P238-I592 WeakPolarHBondContact O-CG2 3.37Å
239T81.9Confident89.6Confident68 Ų6836.9 Ų36.942%0.41719%0.189SC..G310 helixtrans-65.3-21.8-179.7620000114.5N237 L554N237-T239 PolarHBondContact ND2-OG1 2.94Å; N237-T239 PolarHBondContact O-N 3.13Å; N237-T239 VanDerWaalsContact O-N 3.12Å; N237-T239 WeakPolarHBondContact OD1-CB 3.32Å; N237-T239 PolarHBondContact OD1-N 2.71Å; N237-T239 PolarHBondContact OD1-OG1 2.97Å; T239-L554 HydrophobicContact CG2-CB 4.1Å
240S86.1Confident89.1Confident24 Ų2439.3 Ų39.317%0.16820%0.201CC..G310 helixtrans-97.33.3178.7-54.80000112.7D110 N237 P238 D242 G243 R244D110-S240 PolarHBondContact OD2-OG 2.96Å; N237-S240 PolarHBondContact O-N 3.37Å; P238-S240 PolarHBondContact O-N 2.7Å; S240-D242 VanDerWaalsContact C-N 3.33Å; S240-D242 PolarHBondContact O-N 3.21Å; S240-G243 PolarHBondContact O-N 3.12Å; S240-R244 PolarHBondContact O-N 3.14Å; S240-R244 VanDerWaalsContact O-N 3.09Å
241I90.8Very high88Confident2 Ų238.6 Ų38.61%0.0120%0.201CC..Hα-helixtrans-63.1-35-171.6-163.3171.7000113.2I236 N237 P238 G243 R244 V245 I558 V588 H589 I592I236-I241 HydrophobicContact CG2-CB 4.22Å; I236-I241 HydrophobicContact CG2-CG1 4.35Å; N237-I241 PolarHBondContact O-N 3.44Å; P238-I241 WeakPolarHBondContact O-CB 3.46Å; P238-I241 WeakPolarHBondContact O-CG2 3.43Å; P238-I241 PolarHBondContact O-N 3.41Å; P238-I241 VanDerWaalsContact O-N 3.14Å; I241-G243 PolarHBondContact O-N 2.8Å; I241-R244 WeakPolarHBondContact O-CB 3.35Å; I241-R244 PolarHBondContact O-N 3.23Å; I241-R244 VanDerWaalsContact O-N 3.16Å; I241-V245 HydrophobicContact CG1-CG2 4.25Å; I241-V245 VanDerWaalsContact O-CG2 3.31Å; I241-V245 WeakPolarHBondContact O-CG2 3.41Å; I241-V245 PolarHBondContact O-N 3.41Å; I241-I558 HydrophobicContact CD1-CD1 4.03Å; I241-V588 HydrophobicContact CD1-CB 4.07Å; I241-V588 HydrophobicContact CD1-CG1 3.59Å; I241-H589 HydrophobicContact CD1-CB 4.14Å; I241-H589 HydrophobicContact CG1-CB 4.33Å; I241-H589 HydrophobicContact CG2-CB 3.99Å; I241-I592 HydrophobicContact CB-CD1 4.33Å; I241-I592 HydrophobicContact CD1-CD1 3.87Å; I241-I592 HydrophobicContact CG2-CB 4.45Å; I241-I592 HydrophobicContact CG2-CD1 3.93Å; I241-I592 HydrophobicContact CG2-CG2 4.33Å
242D91.2Very high86.3Confident64 Ų6446.9 Ų46.934%0.34224%0.239SC..Hα-helixtrans-58.1-48.1176.5174.664000111.3S240 R244 V245 K246 H589S240-D242 VanDerWaalsContact C-N 3.33Å; S240-D242 PolarHBondContact O-N 3.21Å; D242-R244 VanDerWaalsContact C-N 3.33Å; D242-R244 PolarHBondContact O-N 2.72Å; D242-V245 PolarHBondContact O-N 3.36Å; D242-K246 WeakPolarHBondContact O-CG 3.47Å; D242-K246 PolarHBondContact O-N 3.21Å; D242-K246 WeakPolarHBondContact OD1-CE 3.43Å; D242-K246 IonicContact OD1-NZ 3.32Å; D242-K246 PolarHBondContact OD1-NZ 2.87Å; D242-K246 WeakPolarHBondContact OD2-CE 2.9Å; D242-K246 IonicContact OD2-NZ 3.03Å; D242-K246 PolarHBondContact OD2-NZ 3.48Å; D242-H589 IonicContact OD1-CE1 3.76Å; D242-H589 PolarHBondContact OD1-CE1 3Å; D242-H589 IonicContact OD1-NE2 3.68Å
243G88.6Confident84.8Confident15 Ų1550.3 Ų50.316%0.15526%0.258CS..Hα-helixtrans-62.2-39.8175.700000112.3S240 I241 K246 K247S240-G243 PolarHBondContact O-N 3.12Å; I241-G243 PolarHBondContact O-N 2.8Å; G243-K246 PolarHBondContact O-N 3.04Å; G243-K247 WeakPolarHBondContact O-CB 3.48Å; G243-K247 PolarHBondContact O-N 3.14Å
244R90.7Very high83.5Confident22 Ų2257.5 Ų57.58%0.08329%0.29CS..Hα-helixtrans-62.9-45.2175.117961.864.9906.9112.2T233 K235 I236 S240 I241 D242 K247 L248 Y585T233-R244 PolarHBondContact O-NH1 3.34Å; K235-R244 PolarHBondContact O-NH2 3.02Å; I236-R244 HydrophobicContact CD1-CG 3.83Å; I236-R244 HydrophobicContact CG1-CG 3.95Å; I236-R244 VanDerWaalsContact CG1-CZ 3.47Å; I236-R244 HydrophobicContact CG2-CB 4.46Å; S240-R244 PolarHBondContact O-N 3.14Å; S240-R244 VanDerWaalsContact O-N 3.09Å; I241-R244 WeakPolarHBondContact O-CB 3.35Å; I241-R244 PolarHBondContact O-N 3.23Å; I241-R244 VanDerWaalsContact O-N 3.16Å; D242-R244 VanDerWaalsContact C-N 3.33Å; D242-R244 PolarHBondContact O-N 2.72Å; R244-K247 PolarHBondContact O-N 3.17Å; R244-L248 HydrophobicContact CG-CD1 3.93Å; R244-L248 HydrophobicContact CG-CG 4.39Å; R244-L248 WeakPolarHBondContact O-CG 3.22Å; R244-L248 PolarHBondContact O-N 3.35Å; R244-Y585 HydrophobicContact CG-CE1 4.04Å
245V92.7Very high82.4Confident18 Ų1861 Ų6111%0.10932%0.316CS..Hα-helixtrans-61.1-45.7179.2170.10000110.4I241 D242 K247 L248 Q249 F258 Y585 H589I241-V245 HydrophobicContact CG1-CG2 4.25Å; I241-V245 VanDerWaalsContact O-CG2 3.31Å; I241-V245 WeakPolarHBondContact O-CG2 3.41Å; I241-V245 PolarHBondContact O-N 3.41Å; D242-V245 PolarHBondContact O-N 3.36Å; V245-K247 PolarHBondContact O-N 3.42Å; V245-L248 PolarHBondContact O-N 2.88Å; V245-Q249 WeakPolarHBondContact O-CB 3.31Å; V245-Q249 PolarHBondContact O-N 3.43Å; V245-F258 HydrophobicContact CG1-CZ 4.45Å; V245-Y585 HydrophobicContact CG2-CD1 4.22Å; V245-H589 HydrophobicContact CG2-CB 4.46Å
246K92.5Very high82Confident117 Ų11759.2 Ų59.251%0.50931%0.313SS..Hα-helixtrans-58.2-48175-72.4169.2179.9164.20111.4D242 G243 L248 Q249 E250D242-K246 WeakPolarHBondContact O-CG 3.47Å; D242-K246 PolarHBondContact O-N 3.21Å; D242-K246 WeakPolarHBondContact OD1-CE 3.43Å; D242-K246 IonicContact OD1-NZ 3.32Å; D242-K246 PolarHBondContact OD1-NZ 2.87Å; D242-K246 WeakPolarHBondContact OD2-CE 2.9Å; D242-K246 IonicContact OD2-NZ 3.03Å; D242-K246 PolarHBondContact OD2-NZ 3.48Å; G243-K246 PolarHBondContact O-N 3.04Å; K246-L248 VanDerWaalsContact C-N 3.35Å; K246-L248 PolarHBondContact O-N 3.5Å; K246-Q249 WeakPolarHBondContact O-CB 3.35Å; K246-Q249 PolarHBondContact O-N 3.15Å; K246-Q249 VanDerWaalsContact O-N 3.1Å; K246-E250 PolarHBondContact O-N 3.15Å; K246-E250 VanDerWaalsContact O-N 3.14Å
247K88.1Confident82Confident52 Ų5259.2 Ų59.223%0.22631%0.314CS..Hα-helixtrans-62-38.6179.6-168.371.7-1631740113.4E114 R115 G243 R244 V245 Q249 E250E114-K247 VanDerWaalsContact OE1-CE 3.29Å; E114-K247 WeakPolarHBondContact OE1-CE 3.14Å; E114-K247 IonicContact OE1-NZ 3.89Å; E114-K247 PolarHBondContact OE1-NZ 3.18Å; E114-K247 WeakPolarHBondContact OE2-CE 3.26Å; E114-K247 IonicContact OE2-NZ 3.34Å; R115-K247 HydrophobicContact CG-CG 4.41Å; G243-K247 WeakPolarHBondContact O-CB 3.48Å; G243-K247 PolarHBondContact O-N 3.14Å; R244-K247 PolarHBondContact O-N 3.17Å; V245-K247 PolarHBondContact O-N 3.42Å; K247-Q249 VanDerWaalsContact C-N 3.3Å; K247-E250 WeakPolarHBondContact CD-OE2 3.49Å; K247-E250 IonicContact NZ-OE2 3.38Å; K247-E250 PolarHBondContact NZ-OE2 2.8Å
248L90.1Very high82.5Confident3 Ų359.1 Ų59.12%0.01631%0.313CS..Hα-helixtrans-73.5-23.4177.3-70.4173.1000112.8R244 V245 K246 G257 F258 E261 Y585R244-L248 HydrophobicContact CG-CD1 3.93Å; R244-L248 HydrophobicContact CG-CG 4.39Å; R244-L248 WeakPolarHBondContact O-CG 3.22Å; R244-L248 PolarHBondContact O-N 3.35Å; V245-L248 PolarHBondContact O-N 2.88Å; K246-L248 VanDerWaalsContact C-N 3.35Å; K246-L248 PolarHBondContact O-N 3.5Å; L248-G257 VanDerWaalsContact O-CA 3.28Å; L248-G257 WeakPolarHBondContact O-CA 3.28Å; L248-F258 HydrophobicContact CB-CD1 4.03Å; L248-F258 HydrophobicContact CB-CD2 3.76Å; L248-F258 HydrophobicContact CB-CE1 3.79Å; L248-F258 HydrophobicContact CB-CE2 3.52Å; L248-F258 HydrophobicContact CB-CG 4.01Å; L248-F258 HydrophobicContact CB-CZ 3.54Å; L248-F258 HydrophobicContact CD1-CD1 3.92Å; L248-F258 HydrophobicContact CD1-CE1 3.54Å; L248-F258 HydrophobicContact CD1-CZ 4.02Å; L248-F258 HydrophobicContact CG-CE1 4.31Å; L248-F258 HydrophobicContact CG-CZ 4.45Å; L248-F258 WeakPolarHBondContact O-CD2 3.43Å; L248-F258 PolarHBondContact O-N 2.89Å; L248-E261 HydrophobicContact CD2-CG 4.38Å; L248-Y585 HydrophobicContact CD1-CD1 4.19Å; L248-Y585 HydrophobicContact CD1-CE1 3.59Å; L248-Y585 HydrophobicContact CD1-CE2 4.28Å
249Q89.7Confident82.6Confident105 Ų10562.9 Ų62.949%0.49133%0.327SS..Hα-helixtrans-80-26.7176.6-164.5104.9-5.500113V245 K246 K247 G251 F258V245-Q249 WeakPolarHBondContact O-CB 3.31Å; V245-Q249 PolarHBondContact O-N 3.43Å; K246-Q249 WeakPolarHBondContact O-CB 3.35Å; K246-Q249 PolarHBondContact O-N 3.15Å; K246-Q249 VanDerWaalsContact O-N 3.1Å; K247-Q249 VanDerWaalsContact C-N 3.3Å; Q249-G251 PolarHBondContact O-N 2.9Å; Q249-F258 HydrophobicContact CB-CE2 4.44Å
250E83.6Confident83Confident121 Ų12161.3 Ų61.357%0.56532%0.315SS*.  trans-62.7-15.4176.7-74.1169.3-165.700113.5K246 K247 E252K246-E250 PolarHBondContact O-N 3.15Å; K246-E250 VanDerWaalsContact O-N 3.14Å; K247-E250 WeakPolarHBondContact CD-OE2 3.49Å; K247-E250 IonicContact NZ-OE2 3.38Å; K247-E250 PolarHBondContact NZ-OE2 2.8Å; E250-E252 PolarHBondContact O-N 2.91Å
251G70.7Confident83.2Confident27 Ų2760.2 Ų60.228%0.27831%0.307SS..  trans-65.5101.817500000111.2Q249 S256Q249-G251 PolarHBondContact O-N 2.9Å; G251-S256 WeakPolarHBondContact CA-OG 3.37Å
252E58.2Low83.3Confident193 Ų19360.3 Ų60.390%0.90231%0.308SS*.  trans-75.6-30.8177.1-64.5-172.8162.100112E250E250-E252 PolarHBondContact O-N 2.91Å
253D59.5Low83.2Confident116 Ų11660.2 Ų60.262%0.6231%0.305SS*.SBendtrans-98151.9-177.8-70-26.5000112.7S255 S256D253-S255 WeakPolarHBondContact CB-OG 3.42Å; D253-S255 PolarHBondContact O-N 3.22Å; D253-S256 PolarHBondContact O-N 3.33Å
254Q64.2Low83.2Confident163 Ų16363 Ų6376%0.76231%0.314SS*.THydrogen-bonded Turntrans-62.918.8166.5-63.3179.513.300113.6W259Q254-W259 VanDerWaalsContact C-CD1 3.49Å; Q254-W259 HydrophobicContact CB-CG 4.4Å; Q254-W259 PolarHBondContact O-NE1 3.13Å
255S66.1Low83.1Confident84 Ų8462 Ų6259%0.58731%0.311SS*.THydrogen-bonded Turntrans-114.4-3.3177.9670000113D253D253-S255 WeakPolarHBondContact CB-OG 3.42Å; D253-S255 PolarHBondContact O-N 3.22Å
256S81.3Confident82.7Confident39 Ų3964.8 Ų64.827%0.27332%0.322SS..SBendtrans-144.4174.5-174.668.30000112.7G251 D253 E260G251-S256 WeakPolarHBondContact CA-OG 3.37Å; D253-S256 PolarHBondContact O-N 3.33Å; S256-E260 PolarHBondContact O-N 3.06Å
257G88Confident82.3Confident4 Ų464.8 Ų64.84%0.04132%0.324CS..Hα-helixtrans71.2-142.117100000114.2L248 W259 E260 E261L248-G257 VanDerWaalsContact O-CA 3.28Å; L248-G257 WeakPolarHBondContact O-CA 3.28Å; G257-W259 VanDerWaalsContact C-N 3.31Å; G257-W259 PolarHBondContact O-N 2.96Å; G257-E260 PolarHBondContact O-N 3.18Å; G257-E261 PolarHBondContact O-N 3.34Å
258F91.7Very high81.6Confident5 Ų564.4 Ų64.42%0.02232%0.323CS..Hα-helixtrans-59.9-40.1179.3-72.6-69.8000112.7V245 L248 Q249 E261 F262 E578 Y581 K582 Y585V245-F258 HydrophobicContact CG1-CZ 4.45Å; L248-F258 HydrophobicContact CB-CD1 4.03Å; L248-F258 HydrophobicContact CB-CD2 3.76Å; L248-F258 HydrophobicContact CB-CE1 3.79Å; L248-F258 HydrophobicContact CB-CE2 3.52Å; L248-F258 HydrophobicContact CB-CG 4.01Å; L248-F258 HydrophobicContact CB-CZ 3.54Å; L248-F258 HydrophobicContact CD1-CD1 3.92Å; L248-F258 HydrophobicContact CD1-CE1 3.54Å; L248-F258 HydrophobicContact CD1-CZ 4.02Å; L248-F258 HydrophobicContact CG-CE1 4.31Å; L248-F258 HydrophobicContact CG-CZ 4.45Å; L248-F258 WeakPolarHBondContact O-CD2 3.43Å; L248-F258 PolarHBondContact O-N 2.89Å; Q249-F258 HydrophobicContact CB-CE2 4.44Å; F258-E261 PolarHBondContact O-N 3.43Å; F258-F262 VanDerWaalsContact O-CB 3.31Å; F258-F262 WeakPolarHBondContact O-CB 3.15Å; F258-F262 PolarHBondContact O-N 3.17Å; F258-E578 HydrophobicContact CB-CG 4.14Å; F258-E578 WeakPolarHBondContact CB-OE1 3.2Å; F258-Y581 HydrophobicContact CD1-CD1 4.4Å; F258-K582 HydrophobicContact CD1-CB 4.07Å; F258-K582 HydrophobicContact CD1-CG 4.3Å; F258-K582 HydrophobicContact CD2-CB 4.4Å; F258-K582 HydrophobicContact CD2-CD 3.98Å; F258-K582 HydrophobicContact CD2-CG 4.02Å; F258-K582 HydrophobicContact CE1-CB 4.32Å; F258-K582 HydrophobicContact CE1-CG 4.19Å; F258-K582 HydrophobicContact CE2-CD 4.08Å; F258-K582 HydrophobicContact CE2-CG 3.89Å; F258-K582 HydrophobicContact CG-CB 4.12Å; F258-K582 HydrophobicContact CG-CD 4.46Å; F258-K582 HydrophobicContact CG-CG 4.22Å; F258-K582 HydrophobicContact CZ-CG 3.98Å; F258-Y585 HydrophobicContact CD1-CD2 4.12Å; F258-Y585 HydrophobicContact CD1-CE2 4.33Å; F258-Y585 HydrophobicContact CE1-CD1 4.14Å; F258-Y585 AromaticContact CE1-CD2 3.61Å; F258-Y585 HydrophobicContact CE1-CD2 3.61Å; F258-Y585 HydrophobicContact CE1-CE2 4.08Å; F258-Y585 AromaticContact CE1-CG 3.65Å; F258-Y585 HydrophobicContact CE1-CG 3.65Å; F258-Y585 HydrophobicContact CZ-CG 4.43Å
259W89.6Confident80.8Confident78 Ų7867.3 Ų67.330%0.29534%0.337SS..Hα-helixtrans-63.5-42.8178.9-176.2-91.6000111.9Q254 G257 E261 F262 E263 E578Q254-W259 VanDerWaalsContact C-CD1 3.49Å; Q254-W259 HydrophobicContact CB-CG 4.4Å; Q254-W259 PolarHBondContact O-NE1 3.13Å; G257-W259 VanDerWaalsContact C-N 3.31Å; G257-W259 PolarHBondContact O-N 2.96Å; W259-E261 PolarHBondContact O-N 2.79Å; W259-F262 PolarHBondContact O-N 3.49Å; W259-E263 WeakPolarHBondContact O-CB 3.41Å; W259-E263 PolarHBondContact O-N 2.99Å; W259-E578 HydrophobicContact CB-CG 4.45Å; W259-E578 HydrophobicContact CE3-CB 3.73Å; W259-E578 HydrophobicContact CE3-CG 3.95Å; W259-E578 HydrophobicContact CZ3-CB 4.03Å; W259-E578 PolarHBondContact N-OE1 2.94Å
260E89.6Confident79.4Confident36 Ų3666.6 Ų66.617%0.16834%0.342CS..Hα-helixtrans-57.6-49.2175.2179-150.5140.600112R115 N232 S256 G257 F262 E263 Q264R115-E260 IonicContact CZ-OE1 3.51Å; R115-E260 IonicContact CZ-OE2 3.03Å; R115-E260 IonicContact NH1-OE1 3.12Å; R115-E260 PolarHBondContact NH1-OE1 3.45Å; R115-E260 IonicContact NH1-OE2 3.89Å; R115-E260 PolarHBondContact NH1-OE2 3.23Å; R115-E260 IonicContact NH2-OE1 3.58Å; R115-E260 PolarHBondContact NH2-OE1 3.3Å; R115-E260 IonicContact NH2-OE2 2.85Å; N232-E260 PolarHBondContact ND2-OE1 2.83Å; S256-E260 PolarHBondContact O-N 3.06Å; G257-E260 PolarHBondContact O-N 3.18Å; E260-F262 VanDerWaalsContact C-N 3.32Å; E260-F262 PolarHBondContact O-N 3.5Å; E260-E263 PolarHBondContact O-N 3.41Å; E260-Q264 WeakPolarHBondContact O-CG 3.38Å; E260-Q264 PolarHBondContact O-N 2.66Å; E260-Q264 VanDerWaalsContact O-N 3.09Å; E260-Q264 PolarHBondContact OE1-NE2 2.92Å
261E91.3Very high78.5Confident0 Ų068.6 Ų68.60%035%0.349CS..Hα-helixtrans-64.1-38.7178.8-68-168.4173.400112.1R115 T234 L248 G257 F258 W259 L265 Y581 Y585R115-E261 IonicContact CZ-OE1 2.73Å; R115-E261 IonicContact NE-OE1 2.69Å; R115-E261 PolarHBondContact NE-OE1 3.16Å; R115-E261 IonicContact NH2-OE1 3.06Å; R115-E261 PolarHBondContact NH2-OE1 3.35Å; T234-E261 HydrophobicContact CG2-CG 4.25Å; L248-E261 HydrophobicContact CD2-CG 4.38Å; G257-E261 PolarHBondContact O-N 3.34Å; F258-E261 PolarHBondContact O-N 3.43Å; W259-E261 PolarHBondContact O-N 2.79Å; E261-L265 PolarHBondContact O-N 3.37Å; E261-Y581 HydrophobicContact CB-CE1 3.88Å; E261-Y581 PolarHBondContact OE2-OH 3.01Å; E261-Y585 PolarHBondContact OE2-OH 2.7Å
262F91.8Very high78.3Confident4 Ų469.5 Ų69.52%0.01835%0.346CS..Hα-helixtrans-71.4-39.5178.7-174.5-108.2000112.5F258 W259 E260 Q264 L265 Q266 V575 E578 Y581F258-F262 VanDerWaalsContact O-CB 3.31Å; F258-F262 WeakPolarHBondContact O-CB 3.15Å; F258-F262 PolarHBondContact O-N 3.17Å; W259-F262 PolarHBondContact O-N 3.49Å; E260-F262 VanDerWaalsContact C-N 3.32Å; E260-F262 PolarHBondContact O-N 3.5Å; F262-Q264 VanDerWaalsContact C-N 3.34Å; F262-Q264 PolarHBondContact O-N 3.28Å; F262-L265 VanDerWaalsContact O-CB 3.31Å; F262-L265 WeakPolarHBondContact O-CB 3.35Å; F262-L265 PolarHBondContact O-N 3.46Å; F262-L265 VanDerWaalsContact O-N 3.13Å; F262-Q266 HydrophobicContact CD1-CG 4.38Å; F262-Q266 HydrophobicContact CE1-CG 4.12Å; F262-Q266 WeakPolarHBondContact O-CG 3.28Å; F262-Q266 PolarHBondContact O-N 3.08Å; F262-Q266 VanDerWaalsContact O-N 3.14Å; F262-V575 HydrophobicContact CE2-CG1 4.45Å; F262-E578 HydrophobicContact CD1-CB 4.13Å; F262-E578 HydrophobicContact CG-CB 4.46Å; F262-Y581 HydrophobicContact CB-CD1 4.1Å; F262-Y581 HydrophobicContact CB-CG 4.31Å; F262-Y581 HydrophobicContact CD2-CD1 4.43Å; F262-Y581 HydrophobicContact CD2-CD2 4.06Å; F262-Y581 AromaticContact CD2-CG 3.79Å; F262-Y581 HydrophobicContact CD2-CG 3.79Å; F262-Y581 HydrophobicContact CG-CG 4.44Å
263E89.9Confident79.1Confident63 Ų6367 Ų6729%0.29434%0.338SS..Hα-helixtrans-66.2-36.6177.7-178.855.6-152.500111.3W259 E260 L265 Q266 Q267W259-E263 WeakPolarHBondContact O-CB 3.41Å; W259-E263 PolarHBondContact O-N 2.99Å; E260-E263 PolarHBondContact O-N 3.41Å; E263-L265 VanDerWaalsContact C-N 3.28Å; E263-L265 PolarHBondContact O-N 2.69Å; E263-Q266 WeakPolarHBondContact O-CB 3.44Å; E263-Q266 PolarHBondContact O-N 2.98Å; E263-Q266 VanDerWaalsContact O-N 3.11Å; E263-Q267 WeakPolarHBondContact O-CG 3.48Å; E263-Q267 PolarHBondContact O-N 2.83Å; E263-Q267 PolarHBondContact OE1-NE2 3.21Å
264Q87.8Confident80.5Confident72 Ų7264.7 Ų64.734%0.33632%0.321SS..Hα-helixtrans-60.2-37.2171.1-72.6173.518.300112.4E260 F262 Q266 Q267 Q268E260-Q264 WeakPolarHBondContact O-CG 3.38Å; E260-Q264 PolarHBondContact O-N 2.66Å; E260-Q264 VanDerWaalsContact O-N 3.09Å; E260-Q264 PolarHBondContact OE1-NE2 2.92Å; F262-Q264 VanDerWaalsContact C-N 3.34Å; F262-Q264 PolarHBondContact O-N 3.28Å; Q264-Q266 VanDerWaalsContact C-N 3.34Å; Q264-Q267 PolarHBondContact O-N 3.36Å; Q264-Q268 WeakPolarHBondContact O-CG 3.32Å; Q264-Q268 PolarHBondContact O-N 3.14Å; Q264-Q268 VanDerWaalsContact O-N 3.1Å
265L87.8Confident81.9Confident2 Ų259.3 Ų59.31%0.0130%0.302CS..Hα-helixtrans-64.9-38.3173.7-75167.2000112.1E261 F262 E263 Q268 E269 R561 V564 Q565 R568 Y581E261-L265 PolarHBondContact O-N 3.37Å; F262-L265 VanDerWaalsContact O-CB 3.31Å; F262-L265 WeakPolarHBondContact O-CB 3.35Å; F262-L265 PolarHBondContact O-N 3.46Å; F262-L265 VanDerWaalsContact O-N 3.13Å; E263-L265 VanDerWaalsContact C-N 3.28Å; E263-L265 PolarHBondContact O-N 2.69Å; L265-Q268 PolarHBondContact O-N 3.48Å; L265-E269 PolarHBondContact O-N 3.27Å; L265-R561 HydrophobicContact CD1-CG 3.9Å; L265-R561 HydrophobicContact CD2-CG 3.71Å; L265-R561 WeakPolarHBondContact CD2-O 3.43Å; L265-R561 HydrophobicContact CG-CG 3.65Å; L265-V564 HydrophobicContact CD1-CB 4.06Å; L265-V564 HydrophobicContact CD1-CG1 3.89Å; L265-Q565 HydrophobicContact CD2-CB 3.8Å; L265-R568 PolarHBondContact O-NH1 3.44Å; L265-Y581 HydrophobicContact CD1-CD2 4.02Å; L265-Y581 HydrophobicContact CD1-CE2 3.52Å
266Q85.7Confident83.3Confident76 Ų7659.2 Ų59.236%0.35529%0.288SS..Hα-helixtrans-63.3-44176.8-60.4-88.487.800110.7F262 E263 Q264 Q268 E269F262-Q266 HydrophobicContact CD1-CG 4.38Å; F262-Q266 HydrophobicContact CE1-CG 4.12Å; F262-Q266 WeakPolarHBondContact O-CG 3.28Å; F262-Q266 PolarHBondContact O-N 3.08Å; F262-Q266 VanDerWaalsContact O-N 3.14Å; E263-Q266 WeakPolarHBondContact O-CB 3.44Å; E263-Q266 PolarHBondContact O-N 2.98Å; E263-Q266 VanDerWaalsContact O-N 3.11Å; Q264-Q266 VanDerWaalsContact C-N 3.34Å; Q266-Q268 VanDerWaalsContact C-N 3.28Å; Q266-Q268 PolarHBondContact O-N 3.13Å; Q266-E269 PolarHBondContact O-N 3.13Å
267Q83.2Confident84Confident117 Ų11764.2 Ų64.255%0.54731%0.305SS..Hα-helixtrans-68-26.9178.7-67.5172.614.800112.9E263 Q264 C270E263-Q267 WeakPolarHBondContact O-CG 3.48Å; E263-Q267 PolarHBondContact O-N 2.83Å; E263-Q267 PolarHBondContact OE1-NE2 3.21Å; Q264-Q267 PolarHBondContact O-N 3.36Å; Q267-C270 PolarHBondContact O-SG 3.34Å
268Q74.9Confident84.5Confident45 Ų4566.3 Ų66.321%0.2131%0.314CS..Hα-helixtrans-75.8-24.8175.7-74.4173.7-5.300113.2Q264 L265 Q266 C270 K271 Q565Q264-Q268 WeakPolarHBondContact O-CG 3.32Å; Q264-Q268 PolarHBondContact O-N 3.14Å; Q264-Q268 VanDerWaalsContact O-N 3.1Å; L265-Q268 PolarHBondContact O-N 3.48Å; Q266-Q268 VanDerWaalsContact C-N 3.28Å; Q266-Q268 PolarHBondContact O-N 3.13Å; Q268-C270 PolarHBondContact O-N 3.38Å; Q268-C270 VanDerWaalsContact O-N 3.16Å; Q268-K271 WeakPolarHBondContact O-CB 3.47Å; Q268-K271 PolarHBondContact O-N 3.1Å; Q268-Q565 VanDerWaalsContact OE1-OE1 3.09Å
269E71.9Confident84.8Confident64 Ų6466.1 Ų66.130%0.29931%0.313SS..Hα-helixtrans-60-28.4178.8-69.7-166.7152.100112.6L265 Q266 K271 H272 R568 G573L265-E269 PolarHBondContact O-N 3.27Å; Q266-E269 PolarHBondContact O-N 3.13Å; E269-K271 PolarHBondContact O-N 3.43Å; E269-H272 PolarHBondContact O-N 3.35Å; E269-H272 VanDerWaalsContact O-N 3.14Å; E269-R568 WeakPolarHBondContact OE1-CD 3.46Å; E269-R568 IonicContact OE1-CZ 3.79Å; E269-R568 IonicContact OE1-NE 3.98Å; E269-R568 PolarHBondContact OE1-NE 2.95Å; E269-R568 IonicContact OE1-NH1 3.79Å; E269-R568 PolarHBondContact OE1-NH1 3Å; E269-R568 IonicContact OE1-NH2 3.79Å; E269-R568 IonicContact OE2-NH1 2.76Å; E269-G573 WeakPolarHBondContact OE1-CA 3.5Å; E269-G573 PolarHBondContact OE1-N 3.25Å
270C61.7Low85.2Confident89 Ų8967.2 Ų67.260%0.60132%0.322SS*.THydrogen-bonded Turntrans-68.5-18.3177.1780000113.3Q267 Q268Q267-C270 PolarHBondContact O-SG 3.34Å; Q268-C270 PolarHBondContact O-N 3.38Å; Q268-C270 VanDerWaalsContact O-N 3.16Å
271K63.9Low85.6Confident163 Ų16369.6 Ų69.671%0.70933%0.329SS*.THydrogen-bonded Turntrans-78.8-22.8174.3-61.4-174.7176.9-1770112.3Q268 E269Q268-K271 WeakPolarHBondContact O-CB 3.47Å; Q268-K271 PolarHBondContact O-N 3.1Å; E269-K271 PolarHBondContact O-N 3.43Å
272H66.2Low85.9Confident46 Ų4673.9 Ų73.921%0.21336%0.357CS..  trans-108.259.2-173.3-67.9165.8000111.3E269 Y274 E381E269-H272 PolarHBondContact O-N 3.35Å; E269-H272 VanDerWaalsContact O-N 3.14Å; H272-Y274 HydrophobicContact CB-CD2 3.96Å; H272-Y274 HydrophobicContact CB-CE2 3.55Å; H272-Y274 AromaticContact CG-CE2 3.89Å; H272-Y274 PolarHBondContact O-N 2.85Å; H272-E381 IonicContact CE1-OE1 3.81Å; H272-E381 PolarHBondContact CE1-OE1 3.05Å
273L75.4Confident86.2Confident140 Ų14077.9 Ų77.973%0.73338%0.376SS*.  trans-75.761.3175.9-66.7172.9000111.6
274Y89.1Confident86.5Confident69 Ų6974.9 Ų74.927%0.27136%0.362SS..  trans-66.6146.9175.6-60.5-64.2000111.6H272 F296 H298 S569H272-Y274 HydrophobicContact CB-CD2 3.96Å; H272-Y274 HydrophobicContact CB-CE2 3.55Å; H272-Y274 AromaticContact CG-CE2 3.89Å; H272-Y274 PolarHBondContact O-N 2.85Å; Y274-F296 HydrophobicContact CD2-CD2 4.04Å; Y274-F296 HydrophobicContact CD2-CE1 4.3Å; Y274-F296 AromaticContact CD2-CE2 3.7Å; Y274-F296 HydrophobicContact CD2-CE2 3.7Å; Y274-F296 HydrophobicContact CD2-CG 4.49Å; Y274-F296 AromaticContact CD2-CZ 3.84Å; Y274-F296 HydrophobicContact CD2-CZ 3.84Å; Y274-F296 HydrophobicContact CE2-CE2 4.47Å; Y274-F296 HydrophobicContact CG-CD2 4.5Å; Y274-H298 AromaticContact CD1-CE1 3.64Å; Y274-H298 AromaticContact CD2-CE1 3.84Å; Y274-H298 AromaticContact CG-CE1 3.44Å; Y274-H298 VanDerWaalsContact CG-CE1 3.44Å; Y274-S569 WeakPolarHBondContact CE2-O 3.28Å
275S93.5Very high87Confident50 Ų5079.3 Ų79.335%0.3538%0.375SS..  trans-65142.5-179.2-171.90000111.1K277 F296 D297S275-K277 WeakPolarHBondContact OG-CG 3.38Å; S275-F296 WeakPolarHBondContact O-CA 3.37Å; S275-D297 WeakPolarHBondContact CB-OD2 3.49Å; S275-D297 PolarHBondContact O-N 3.01Å; S275-D297 PolarHBondContact OG-OD2 3.46Å
276R95.3Very high87.5Confident82 Ų8283.5 Ų83.531%0.30940%0.403SS..  trans-13526178.5-69.1165.3-78-176.5-1.4110.7E278 G279 Q280 L294 P295 F296 D297R276-E278 VanDerWaalsContact C-N 3.3Å; R276-E278 PolarHBondContact O-N 3.13Å; R276-G279 PolarHBondContact O-N 2.96Å; R276-Q280 WeakPolarHBondContact O-CG 3.16Å; R276-Q280 PolarHBondContact O-N 2.77Å; R276-L294 HydrophobicContact CB-CB 4.1Å; R276-L294 HydrophobicContact CB-CD1 4.4Å; R276-L294 HydrophobicContact CG-CB 4.34Å; R276-P295 WeakPolarHBondContact CG-O 3.31Å; R276-F296 HydrophobicContact CG-CD1 3.8Å; R276-F296 HydrophobicContact CG-CE1 4.4Å; R276-D297 VanDerWaalsContact C-OD1 3.28Å; R276-D297 WeakPolarHBondContact CA-OD1 3.48Å; R276-D297 PolarHBondContact N-OD2 2.82Å
277K96.8Very high88.1Confident143 Ų14381.6 Ų81.662%0.62239%0.393SS*.Hα-helixtrans-63.5-37.9-169.9-72.8174.8-176.4179.80110.9S275 G279 Q280 R281 D297S275-K277 WeakPolarHBondContact OG-CG 3.38Å; K277-G279 VanDerWaalsContact C-N 3.31Å; K277-G279 PolarHBondContact O-N 3.41Å; K277-Q280 PolarHBondContact O-N 2.86Å; K277-R281 PolarHBondContact O-N 3.24Å; K277-D297 PolarHBondContact N-OD1 3.28Å; K277-D297 VanDerWaalsContact N-OD1 3.13Å; K277-D297 PolarHBondContact N-OD2 3.28Å
278E97.7Very high88.8Confident48 Ų4876.8 Ų76.822%0.22437%0.372CS..Hα-helixtrans-62.2-41.2-179.6-66.8-55.5136.100111.3R276 Q280 R281 N284 D297 Y315R276-E278 VanDerWaalsContact C-N 3.3Å; R276-E278 PolarHBondContact O-N 3.13Å; E278-Q280 VanDerWaalsContact C-N 3.25Å; E278-Q280 PolarHBondContact O-N 2.9Å; E278-R281 WeakPolarHBondContact O-CB 3.33Å; E278-R281 PolarHBondContact O-N 3.2Å; E278-R281 WeakPolarHBondContact OE2-CD 3.45Å; E278-R281 IonicContact OE2-CZ 2.79Å; E278-R281 IonicContact OE2-NE 3.51Å; E278-R281 IonicContact OE2-NH1 2.71Å; E278-R281 PolarHBondContact OE2-NH1 3.22Å; E278-N284 WeakPolarHBondContact O-CB 3.41Å; E278-N284 PolarHBondContact O-ND2 3.36Å; E278-D297 WeakPolarHBondContact CB-OD1 3.19Å; E278-D297 PolarHBondContact N-OD1 3.01Å; E278-Y315 HydrophobicContact CB-CD2 4.31Å; E278-Y315 HydrophobicContact CB-CE2 4.43Å
279G97.6Very high89.9Confident1 Ų176.7 Ų76.71%0.0137%0.369CS..Hα-helixtrans-69.6-19.2175.700000114.7R276 K277 N288 Y315R276-G279 PolarHBondContact O-N 2.96Å; K277-G279 VanDerWaalsContact C-N 3.31Å; K277-G279 PolarHBondContact O-N 3.41Å; G279-N288 PolarHBondContact O-ND2 3.07Å; G279-Y315 VanDerWaalsContact CA-CE2 3.49Å; G279-Y315 VanDerWaalsContact CA-OH 3.25Å; G279-Y315 WeakPolarHBondContact CA-OH 3.28Å
280Q97.5Very high91.1Very high102 Ų10277.2 Ų77.248%0.47737%0.369SS..Hα-helixtrans-87.9-12.3179.9-68.5174.2-13.400113.7R276 K277 E278 R285 L294R276-Q280 WeakPolarHBondContact O-CG 3.16Å; R276-Q280 PolarHBondContact O-N 2.77Å; K277-Q280 PolarHBondContact O-N 2.86Å; E278-Q280 VanDerWaalsContact C-N 3.25Å; E278-Q280 PolarHBondContact O-N 2.9Å; Q280-R285 PolarHBondContact O-NE 3.27Å; Q280-R285 PolarHBondContact O-NH2 3.11Å; Q280-L294 HydrophobicContact CG-CD1 3.47Å; Q280-L294 VanDerWaalsContact CG-CD1 3.47Å
281R98.1Very high92.7Very high85 Ų8582.3 Ų82.332%0.32138%0.381SS..SBendtrans-57.6139.8-179.7-69.3176.365.41762111.5K277 E278 E283 N284 R285K277-R281 PolarHBondContact O-N 3.24Å; E278-R281 WeakPolarHBondContact O-CB 3.33Å; E278-R281 PolarHBondContact O-N 3.2Å; E278-R281 WeakPolarHBondContact OE2-CD 3.45Å; E278-R281 IonicContact OE2-CZ 2.79Å; E278-R281 IonicContact OE2-NE 3.51Å; E278-R281 IonicContact OE2-NH1 2.71Å; E278-R281 PolarHBondContact OE2-NH1 3.22Å; R281-E283 IonicContact NE-OE2 3.57Å; R281-E283 PolarHBondContact O-N 3.18Å; R281-E283 VanDerWaalsContact O-N 3.14Å; R281-N284 HydrophobicContact CB-CB 4.26Å; R281-N284 PolarHBondContact O-N 2.93Å; R281-R285 WeakPolarHBondContact O-CG 3.32Å; R281-R285 PolarHBondContact O-N 3.22Å; R281-R285 VanDerWaalsContact O-N 3.08Å
282P98Very high94Very high91 Ų9180 Ų8059%0.59138%0.376SS*.THydrogen-bonded Turntrans-50.9-39.1-177.8-28.135.8000114P286P282-P286 WeakPolarHBondContact O-CD 3.19Å
283E97.4Very high95.4Very high88 Ų8878.8 Ų78.841%0.41137%0.371SS..THydrogen-bonded Turntrans-76.3-25.5-176.3-48.888172.500112.5R281 P311R281-E283 IonicContact NE-OE2 3.57Å; R281-E283 PolarHBondContact O-N 3.18Å; R281-E283 VanDerWaalsContact O-N 3.14Å; E283-P311 HydrophobicContact CB-CB 4.4Å; E283-P311 HydrophobicContact CG-CB 3.98Å
284N98.3Very high96.4Very high0 Ų072.6 Ų72.60%034%0.339CS..THydrogen-bonded Turntrans-91.4-21.5-179.3-68.7-19.7000113.1E278 R281 P286 K287 N288 G312 Y315E278-N284 WeakPolarHBondContact O-CB 3.41Å; E278-N284 PolarHBondContact O-ND2 3.36Å; R281-N284 HydrophobicContact CB-CB 4.26Å; R281-N284 PolarHBondContact O-N 2.93Å; N284-P286 VanDerWaalsContact C-CD 3.48Å; N284-K287 WeakPolarHBondContact O-CB 3.42Å; N284-K287 PolarHBondContact O-N 3.33Å; N284-N288 PolarHBondContact O-ND2 3.09Å; N284-G312 WeakPolarHBondContact OD1-CA 3.4Å; N284-Y315 HydrophobicContact CB-CD1 3.57Å; N284-Y315 HydrophobicContact CB-CD2 4.19Å; N284-Y315 HydrophobicContact CB-CE1 3.76Å; N284-Y315 HydrophobicContact CB-CE2 4.36Å; N284-Y315 HydrophobicContact CB-CG 3.8Å; N284-Y315 VanDerWaalsContact CG-CB 3.44Å; N284-Y315 WeakPolarHBondContact ND2-CB 3.27Å; N284-Y315 WeakPolarHBondContact ND2-CD2 3.49Å; N284-Y315 WeakPolarHBondContact OD1-CB 3.36Å
285R97.8Very high96.8Very high164 Ų16469.3 Ų69.362%0.61933%0.326SS*.G310 helixtrans-52-44.9179-76.4174-171.9-169.9-0.2113.8Q280 R281 K287 N288Q280-R285 PolarHBondContact O-NE 3.27Å; Q280-R285 PolarHBondContact O-NH2 3.11Å; R281-R285 WeakPolarHBondContact O-CG 3.32Å; R281-R285 PolarHBondContact O-N 3.22Å; R281-R285 VanDerWaalsContact O-N 3.08Å; R285-K287 PolarHBondContact O-N 2.73Å; R285-N288 PolarHBondContact O-N 2.9Å; R285-N288 VanDerWaalsContact O-N 3.15Å
286P97.9Very high97Very high91 Ų9167.1 Ų67.159%0.59131%0.31SS*.G310 helixtrans-67.2-19.7179-20.134000114P282 N284 N288P282-P286 WeakPolarHBondContact O-CD 3.19Å; N284-P286 VanDerWaalsContact C-CD 3.48Å; P286-N288 VanDerWaalsContact C-N 3.29Å
287K98.3Very high97.1Very high35 Ų3564.9 Ų64.915%0.15230%0.304CS..G310 helixtrans-81-9.5176.5-60.3-176.3168.8-1570112.5N284 R285 G312 Y315 Q396 T402 D405N284-K287 WeakPolarHBondContact O-CB 3.42Å; N284-K287 PolarHBondContact O-N 3.33Å; R285-K287 PolarHBondContact O-N 2.73Å; K287-G312 PolarHBondContact NZ-O 2.8Å; K287-Y315 HydrophobicContact CB-CD1 4.14Å; K287-Y315 HydrophobicContact CB-CE1 4.12Å; K287-Y315 HydrophobicContact CD-CD1 3.96Å; K287-Y315 PolarHBondContact NZ-O 2.9Å; K287-Q396 PolarHBondContact O-NE2 3.23Å; K287-T402 HydrophobicContact CB-CG2 3.97Å; K287-T402 HydrophobicContact CG-CG2 4.36Å; K287-D405 WeakPolarHBondContact CE-OD2 3.21Å; K287-D405 IonicContact NZ-OD1 3.91Å; K287-D405 IonicContact NZ-OD2 3.64Å; K287-D405 PolarHBondContact NZ-OD2 2.92Å
288N98.4Very high97Very high17 Ų1763.2 Ų63.29%0.09130%0.299CS..  trans-93.7125.9179.4-63.6-44.2000111.5G279 N284 R285 P286 Y290 L294 Y315 N317G279-N288 PolarHBondContact O-ND2 3.07Å; N284-N288 PolarHBondContact O-ND2 3.09Å; R285-N288 PolarHBondContact O-N 2.9Å; R285-N288 VanDerWaalsContact O-N 3.15Å; P286-N288 VanDerWaalsContact C-N 3.29Å; N288-Y290 VanDerWaalsContact C-N 3.28Å; N288-Y290 PolarHBondContact O-N 2.96Å; N288-L294 HydrophobicContact CB-CD2 4.15Å; N288-L294 VanDerWaalsContact ND2-CD2 3.26Å; N288-L294 WeakPolarHBondContact ND2-CD2 3.32Å; N288-Y315 PolarHBondContact ND2-OH 3.45Å; N288-Y315 WeakPolarHBondContact OD1-CE1 3.33Å; N288-Y315 PolarHBondContact OD1-OH 3.26Å; N288-N317 PolarHBondContact OD1-ND2 3.44Å
289R97.6Very high97Very high42 Ų4262 Ų6216%0.15830%0.295CS..SBendtrans-65.7-34.2174.3-179.4178.9-70.8-79.6-4.5112.1G397 C398 L399 S430 K431 S530R289-G397 VanDerWaalsContact CZ-O 3.32Å; R289-G397 PolarHBondContact NE-O 3.39Å; R289-G397 PolarHBondContact NH2-O 3.32Å; R289-C398 PolarHBondContact NH2-O 2.81Å; R289-L399 HydrophobicContact CB-CD1 4.48Å; R289-L399 HydrophobicContact CB-CD2 4.15Å; R289-L399 HydrophobicContact CB-CG 4.45Å; R289-L399 HydrophobicContact CG-CD2 4.24Å; R289-S430 PolarHBondContact NH1-O 3.39Å; R289-K431 PolarHBondContact NE-O 3.07Å; R289-K431 PolarHBondContact NH1-O 3.38Å; R289-K431 PolarHBondContact NH2-O 3.02Å; R289-S530 VanDerWaalsContact CD-O 3.32Å; R289-S530 WeakPolarHBondContact CD-O 3.47Å
290Y97.1Very high97Very high76 Ų7664 Ų6430%0.29830%0.302SS..SBendtrans-129.6128.3-179.9-60.7-79.4000110.3N288 N292 I293 S530 A531N288-Y290 VanDerWaalsContact C-N 3.28Å; N288-Y290 PolarHBondContact O-N 2.96Å; Y290-N292 PolarHBondContact O-N 3.45Å; Y290-N292 VanDerWaalsContact O-N 3.1Å; Y290-I293 HydrophobicContact CD2-CD1 3.92Å; Y290-I293 HydrophobicContact CG-CD1 3.91Å; Y290-I293 HydrophobicContact CG-CG1 4.44Å; Y290-I293 PolarHBondContact O-N 3.28Å; Y290-S530 PolarHBondContact OH-OG 2.89Å; Y290-A531 HydrophobicContact CD2-CB 3.85Å; Y290-A531 HydrophobicContact CE2-CB 3.61Å
291K94.5Very high97Very high196 Ų19659.5 Ų59.585%0.85228%0.281SS*.THydrogen-bonded Turntrans-58.8-25-177.665.2179.4-178.9178.40114.6
292N91.2Very high97Very high113 Ų11358.7 Ų58.760%0.60429%0.285SS*.THydrogen-bonded Turntrans-113.54.4-173.964.9-42000113.8Y290Y290-N292 PolarHBondContact O-N 3.45Å; Y290-N292 VanDerWaalsContact O-N 3.1Å
293I95.3Very high97.1Very high21 Ų2154.6 Ų54.611%0.10826%0.258CS..  trans-117.690.1176.8-52.3176.8000106.7Y290 N317 A531 I533Y290-I293 HydrophobicContact CD2-CD1 3.92Å; Y290-I293 HydrophobicContact CG-CD1 3.91Å; Y290-I293 HydrophobicContact CG-CG1 4.44Å; Y290-I293 PolarHBondContact O-N 3.28Å; I293-N317 PolarHBondContact O-ND2 3.05Å; I293-A531 HydrophobicContact CD1-CB 3.63Å; I293-I533 HydrophobicContact CD1-CD1 3.91Å; I293-I533 HydrophobicContact CG1-CD1 4.32Å; I293-I533 HydrophobicContact CG2-CD1 3.92Å; I293-I533 HydrophobicContact CG2-CG1 4.38Å; I293-I533 HydrophobicContact CG2-CG2 4.1Å
294L97Very high97Very high10 Ų1056.5 Ų56.55%0.05226%0.262CS..  trans-116.8148.9-173.5-57.3-179.4000109.3R276 Q280 N288R276-L294 HydrophobicContact CB-CB 4.1Å; R276-L294 HydrophobicContact CB-CD1 4.4Å; R276-L294 HydrophobicContact CG-CB 4.34Å; Q280-L294 HydrophobicContact CG-CD1 3.47Å; Q280-L294 VanDerWaalsContact CG-CD1 3.47Å; N288-L294 HydrophobicContact CB-CD2 4.15Å; N288-L294 VanDerWaalsContact ND2-CD2 3.26Å; N288-L294 WeakPolarHBondContact ND2-CD2 3.32Å
295P98Very high96.6Very high0 Ų062.5 Ų62.50%029%0.294CS..  trans-67.9146.8175.932.5-35.7000110.2R276 R300 Y315 N319R276-P295 WeakPolarHBondContact CG-O 3.31Å; P295-R300 HydrophobicContact CB-CB 4.1Å; P295-R300 HydrophobicContact CG-CB 4.4Å; P295-Y315 VanDerWaalsContact CD-OH 3.26Å; P295-Y315 WeakPolarHBondContact CD-OH 3.44Å; P295-Y315 HydrophobicContact CG-CE2 3.9Å; P295-N319 WeakPolarHBondContact CA-OD1 3.39Å; P295-N319 WeakPolarHBondContact CB-OD1 3.29Å
296F96.7Very high96.2Very high5 Ų555.5 Ų55.52%0.02227%0.273CS..  trans-66.9139.1165.3-63.2-36.7000110.7Y274 S275 R276 H298 T299 R300 N319 R568 Q570 S572Y274-F296 HydrophobicContact CD2-CD2 4.04Å; Y274-F296 HydrophobicContact CD2-CE1 4.3Å; Y274-F296 AromaticContact CD2-CE2 3.7Å; Y274-F296 HydrophobicContact CD2-CE2 3.7Å; Y274-F296 HydrophobicContact CD2-CG 4.49Å; Y274-F296 AromaticContact CD2-CZ 3.84Å; Y274-F296 HydrophobicContact CD2-CZ 3.84Å; Y274-F296 HydrophobicContact CE2-CE2 4.47Å; Y274-F296 HydrophobicContact CG-CD2 4.5Å; S275-F296 WeakPolarHBondContact O-CA 3.37Å; R276-F296 HydrophobicContact CG-CD1 3.8Å; R276-F296 HydrophobicContact CG-CE1 4.4Å; F296-H298 VanDerWaalsContact C-N 3.3Å; F296-H298 VanDerWaalsContact CB-CE1 3.48Å; F296-H298 WeakPolarHBondContact CB-CE1 3.4Å; F296-H298 AromaticContact CD2-CE1 3.71Å; F296-H298 AromaticContact CG-CE1 3.83Å; F296-H298 PolarHBondContact O-N 2.91Å; F296-T299 PolarHBondContact O-N 3.09Å; F296-R300 WeakPolarHBondContact O-CB 3.24Å; F296-R300 PolarHBondContact O-N 2.99Å; F296-N319 PolarHBondContact N-ND2 3.49Å; F296-N319 VanDerWaalsContact N-ND2 3.14Å; F296-N319 PolarHBondContact O-ND2 3.27Å; F296-R568 VanDerWaalsContact CE2-O 3.27Å; F296-R568 WeakPolarHBondContact CE2-O 3.41Å; F296-Q570 WeakPolarHBondContact CD2-O 3.42Å; F296-S572 VanDerWaalsContact CE2-N 3.34Å; F296-S572 VanDerWaalsContact CZ-CB 3.49Å; F296-S572 VanDerWaalsContact CZ-N 3.34Å
297D97.3Very high95.9Very high35 Ų3553.1 Ų53.119%0.18726%0.257CS..THydrogen-bonded Turntrans-65.4-32.8-174.7-63.3-27.3000112.2S275 R276 K277 E278 R300S275-D297 WeakPolarHBondContact CB-OD2 3.49Å; S275-D297 PolarHBondContact O-N 3.01Å; S275-D297 PolarHBondContact OG-OD2 3.46Å; R276-D297 VanDerWaalsContact C-OD1 3.28Å; R276-D297 WeakPolarHBondContact CA-OD1 3.48Å; R276-D297 PolarHBondContact N-OD2 2.82Å; K277-D297 PolarHBondContact N-OD1 3.28Å; K277-D297 VanDerWaalsContact N-OD1 3.13Å; K277-D297 PolarHBondContact N-OD2 3.28Å; E278-D297 WeakPolarHBondContact CB-OD1 3.19Å; E278-D297 PolarHBondContact N-OD1 3.01Å; D297-R300 WeakPolarHBondContact O-CG 3.48Å
298H95.5Very high95.4Very high108 Ų10857.7 Ų57.750%0.529%0.291SS..THydrogen-bonded Turntrans-78.6-20.8-175.465.4-73.9000114.4Y274 F296 S569Y274-H298 AromaticContact CD1-CE1 3.64Å; Y274-H298 AromaticContact CD2-CE1 3.84Å; Y274-H298 AromaticContact CG-CE1 3.44Å; Y274-H298 VanDerWaalsContact CG-CE1 3.44Å; F296-H298 VanDerWaalsContact C-N 3.3Å; F296-H298 VanDerWaalsContact CB-CE1 3.48Å; F296-H298 WeakPolarHBondContact CB-CE1 3.4Å; F296-H298 AromaticContact CD2-CE1 3.71Å; F296-H298 AromaticContact CG-CE1 3.83Å; F296-H298 PolarHBondContact O-N 2.91Å; H298-S569 PolarHBondContact NE2-O 3.28Å
299T96.8Very high95.1Very high23 Ų2363.1 Ų63.114%0.14132%0.319CS..THydrogen-bonded Turntrans-118.45.6178.351.50000112.4F296 N319 L320 Q570F296-T299 PolarHBondContact O-N 3.09Å; T299-N319 CarbonylContact O-C 3.54Å; T299-N319 VanDerWaalsContact O-CA 3.24Å; T299-N319 WeakPolarHBondContact O-CA 3.24Å; T299-N319 PolarHBondContact O-ND2 2.98Å; T299-N319 PolarHBondContact OG1-ND2 3.34Å; T299-L320 PolarHBondContact O-N 3.11Å; T299-Q570 HydrophobicContact CG2-CB 4.37Å; T299-Q570 PolarHBondContact OG1-O 3.08Å
300R98.1Very high94.9Very high43 Ų4364.4 Ų64.416%0.16233%0.332CS..EExtended strand (participates in β ladder)trans-63.6148.5-178.873.9-178.1-179.297.8-11.5110.6P295 F296 D297 V302 D314 A318 N319P295-R300 HydrophobicContact CB-CB 4.1Å; P295-R300 HydrophobicContact CG-CB 4.4Å; F296-R300 WeakPolarHBondContact O-CB 3.24Å; F296-R300 PolarHBondContact O-N 2.99Å; D297-R300 WeakPolarHBondContact O-CG 3.48Å; R300-V302 HydrophobicContact CG-CG2 4.23Å; R300-D314 IonicContact CZ-OD2 2.9Å; R300-D314 PolarHBondContact NH1-O 3.24Å; R300-D314 IonicContact NH1-OD2 2.8Å; R300-D314 PolarHBondContact NH1-OD2 2.9Å; R300-D314 IonicContact NH2-OD2 3.34Å; R300-D314 PolarHBondContact NH2-OD2 3.23Å; R300-A318 VanDerWaalsContact CA-O 3.3Å; R300-A318 WeakPolarHBondContact CA-O 3.38Å; R300-N319 PolarHBondContact N-ND2 2.91Å
301I98.6Very high94.8Very high6 Ų664.6 Ų64.63%0.03134%0.343CS..EExtended strand (participates in β ladder)trans-74.7128.9165.2-56-62000108.9I316 A318 L320 I393 M409 E413I301-I316 HydrophobicContact CB-CG2 4.05Å; I301-I316 HydrophobicContact CG2-CG2 4.28Å; I301-A318 HydrophobicContact CB-CB 4.26Å; I301-A318 HydrophobicContact CG1-CB 3.95Å; I301-A318 PolarHBondContact N-O 3.19Å; I301-L320 HydrophobicContact CD1-CB 3.8Å; I301-L320 HydrophobicContact CD1-CD1 4.46Å; I301-I393 HydrophobicContact CD1-CD1 4.11Å; I301-I393 HydrophobicContact CD1-CG1 4.05Å; I301-I393 HydrophobicContact CG1-CD1 4.46Å; I301-I393 HydrophobicContact CG1-CG1 4.42Å; I301-I393 HydrophobicContact CG1-CG2 4.04Å; I301-M409 HydrophobicContact CB-SD 4.31Å; I301-M409 HydrophobicContact CG1-SD 4.17Å; I301-M409 HydrophobicContact CG2-CG 3.95Å; I301-M409 HydrophobicContact CG2-SD 4.23Å; I301-E413 HydrophobicContact CG2-CG 4.4Å
302V98.3Very high94.8Very high68 Ų6855.4 Ų55.441%0.41230%0.304SS..EExtended strand (participates in β ladder)trans-102.2115.6174.8-171.40000107.8R300 D314 Q412R300-V302 HydrophobicContact CG-CG2 4.23Å; V302-D314 HydrophobicContact CG1-CB 3.93Å; V302-Q412 PolarHBondContact O-NE2 2.72Å
303L98.4Very high95.1Very high6 Ų651 Ų513%0.03128%0.281CS..  trans-69.8134.9176.6-60.6-178.6000110.3D314 I316 D405 M409 F447L303-D314 PolarHBondContact N-O 2.82Å; L303-I316 HydrophobicContact CD1-CB 4.09Å; L303-I316 HydrophobicContact CD1-CG2 4.36Å; L303-I316 HydrophobicContact CD2-CB 4.44Å; L303-I316 HydrophobicContact CD2-CG2 3.89Å; L303-I316 HydrophobicContact CG-CB 4.22Å; L303-I316 HydrophobicContact CG-CG2 3.94Å; L303-D405 HydrophobicContact CD1-CB 3.73Å; L303-M409 HydrophobicContact CD2-CB 3.82Å; L303-F447 HydrophobicContact CB-CE2 4.17Å; L303-F447 HydrophobicContact CB-CZ 3.88Å; L303-F447 HydrophobicContact CD1-CE1 4.33Å; L303-F447 HydrophobicContact CD1-CZ 3.72Å; L303-F447 HydrophobicContact CG-CZ 4.43Å
304R95.5Very high95.2Very high128 Ų12851.9 Ų51.948%0.48329%0.286SS..SBendtrans-105.8149.2-177.8-67.4176.1-89.3175.3-4.8109.3G306 Q412 E413 F447R304-G306 PolarHBondContact O-N 2.79Å; R304-Q412 PolarHBondContact NH2-O 3.38Å; R304-E413 IonicContact CZ-OE1 3.62Å; R304-E413 IonicContact NH2-OE1 2.71Å; R304-E413 PolarHBondContact NH2-OE1 3.05Å; R304-E413 IonicContact NH2-OE2 3.47Å; R304-F447 WeakPolarHBondContact O-CE2 3.07Å
305N90Very high95.2Very high125 Ų12551.4 Ų51.467%0.66828%0.284SS*.SBendtrans6324.2178.6-45.5-54.5000115F447N305-F447 WeakPolarHBondContact O-CD2 3.3Å
306G90.2Very high95.3Very high18 Ų1851.8 Ų51.819%0.18629%0.286CS..  trans-66.3161.9167.900000112.1R304 F447R304-G306 PolarHBondContact O-N 2.79Å; G306-F447 VanDerWaalsContact N-CE2 3.29Å
307P90.2Very high95.4Very high41 Ų4151.6 Ų51.627%0.26629%0.285SS..  trans-55.7122.2173-22.732.8000110.2D309 V310 S313P307-D309 WeakPolarHBondContact CB-OD1 3.21Å; P307-D309 PolarHBondContact O-N 3.48Å; P307-V310 HydrophobicContact CB-CB 4.03Å; P307-V310 HydrophobicContact CB-CG2 3.68Å; P307-V310 HydrophobicContact CG-CG2 4.31Å; P307-V310 PolarHBondContact O-N 2.91Å; P307-S313 WeakPolarHBondContact O-CB 3.25Å; P307-S313 PolarHBondContact O-OG 3.43Å
308P88.7Confident95.4Very high131 Ų13150 Ų5085%0.85128%0.276SS*.THydrogen-bonded Turntrans-70.3-22.2-173.128.4-35.1000112.9
309D92.3Very high95.6Very high130 Ų13044.8 Ų44.870%0.69525%0.252SS*.THydrogen-bonded Turntrans-86.8-7.8179.361.8-50.4000113.5P307 P311P307-D309 WeakPolarHBondContact CB-OD1 3.21Å; P307-D309 PolarHBondContact O-N 3.48Å; D309-P311 WeakPolarHBondContact O-CD 3.42Å
310V92.7Very high95.7Very high69 Ų6945.7 Ų45.742%0.41826%0.256SS..SBendtrans-101.7107.1-179.6178.60000109.7P307 G312 S313P307-V310 HydrophobicContact CB-CB 4.03Å; P307-V310 HydrophobicContact CB-CG2 3.68Å; P307-V310 HydrophobicContact CG-CG2 4.31Å; P307-V310 PolarHBondContact O-N 2.91Å; V310-G312 PolarHBondContact O-N 2.86Å; V310-S313 VanDerWaalsContact O-CB 3.25Å; V310-S313 WeakPolarHBondContact O-CB 3.47Å; V310-S313 PolarHBondContact O-N 3.08Å; V310-S313 VanDerWaalsContact O-N 3.16Å; V310-S313 PolarHBondContact O-OG 2.76Å; V310-S313 VanDerWaalsContact O-OG 3.08Å
311P94.7Very high95.6Very high81 Ų8143.6 Ų43.653%0.52625%0.248SC..THydrogen-bonded Turntrans-59.1135.4175.2-23.134.3000111.5E283 D309 S313E283-P311 HydrophobicContact CB-CB 4.4Å; E283-P311 HydrophobicContact CG-CB 3.98Å; D309-P311 WeakPolarHBondContact O-CD 3.42Å; P311-S313 VanDerWaalsContact C-N 3.32Å
312G95.9Very high95.3Very high3 Ų348 Ų483%0.03127%0.268CS..THydrogen-bonded Turntrans79.111.6-177.400000114.5N284 K287 V310 D314 Y315N284-G312 WeakPolarHBondContact OD1-CA 3.4Å; K287-G312 PolarHBondContact NZ-O 2.8Å; V310-G312 PolarHBondContact O-N 2.86Å; G312-D314 PolarHBondContact O-N 3.46Å; G312-Y315 WeakPolarHBondContact O-CB 3.43Å; G312-Y315 PolarHBondContact O-N 3.02Å; G312-Y315 VanDerWaalsContact O-N 3.16Å
313S96.3Very high94.8Very high20 Ų2044.7 Ų44.714%0.1425%0.249CC..THydrogen-bonded Turntrans-64.2-23.117261.90000113P307 V310 P311 Y315 F447P307-S313 WeakPolarHBondContact O-CB 3.25Å; P307-S313 PolarHBondContact O-OG 3.43Å; V310-S313 VanDerWaalsContact O-CB 3.25Å; V310-S313 WeakPolarHBondContact O-CB 3.47Å; V310-S313 PolarHBondContact O-N 3.08Å; V310-S313 VanDerWaalsContact O-N 3.16Å; V310-S313 PolarHBondContact O-OG 2.76Å; V310-S313 VanDerWaalsContact O-OG 3.08Å; P311-S313 VanDerWaalsContact C-N 3.32Å; S313-Y315 VanDerWaalsContact C-N 3.31Å; S313-F447 WeakPolarHBondContact O-CZ 3.3Å
314D97.5Very high93.6Very high39 Ų3947.4 Ų47.421%0.20927%0.268CS..THydrogen-bonded Turntrans-83-5.8175.377.7-53.4000113.5R300 V302 L303 G312R300-D314 IonicContact CZ-OD2 2.9Å; R300-D314 PolarHBondContact NH1-O 3.24Å; R300-D314 IonicContact NH1-OD2 2.8Å; R300-D314 PolarHBondContact NH1-OD2 2.9Å; R300-D314 IonicContact NH2-OD2 3.34Å; R300-D314 PolarHBondContact NH2-OD2 3.23Å; V302-D314 HydrophobicContact CG1-CB 3.93Å; L303-D314 PolarHBondContact N-O 2.82Å; G312-D314 PolarHBondContact O-N 3.46Å
315Y98.5Very high91.9Very high0 Ų044.3 Ų44.30%026%0.257CS..EExtended strand (participates in β ladder)trans-99.4130.6-170.2-179.2-94.8000113.2E278 G279 N284 K287 N288 P295 G312 S313E278-Y315 HydrophobicContact CB-CD2 4.31Å; E278-Y315 HydrophobicContact CB-CE2 4.43Å; G279-Y315 VanDerWaalsContact CA-CE2 3.49Å; G279-Y315 VanDerWaalsContact CA-OH 3.25Å; G279-Y315 WeakPolarHBondContact CA-OH 3.28Å; N284-Y315 HydrophobicContact CB-CD1 3.57Å; N284-Y315 HydrophobicContact CB-CD2 4.19Å; N284-Y315 HydrophobicContact CB-CE1 3.76Å; N284-Y315 HydrophobicContact CB-CE2 4.36Å; N284-Y315 HydrophobicContact CB-CG 3.8Å; N284-Y315 VanDerWaalsContact CG-CB 3.44Å; N284-Y315 WeakPolarHBondContact ND2-CB 3.27Å; N284-Y315 WeakPolarHBondContact ND2-CD2 3.49Å; N284-Y315 WeakPolarHBondContact OD1-CB 3.36Å; K287-Y315 HydrophobicContact CB-CD1 4.14Å; K287-Y315 HydrophobicContact CB-CE1 4.12Å; K287-Y315 HydrophobicContact CD-CD1 3.96Å; K287-Y315 PolarHBondContact NZ-O 2.9Å; N288-Y315 PolarHBondContact ND2-OH 3.45Å; N288-Y315 WeakPolarHBondContact OD1-CE1 3.33Å; N288-Y315 PolarHBondContact OD1-OH 3.26Å; P295-Y315 VanDerWaalsContact CD-OH 3.26Å; P295-Y315 WeakPolarHBondContact CD-OH 3.44Å; P295-Y315 HydrophobicContact CG-CE2 3.9Å; G312-Y315 WeakPolarHBondContact O-CB 3.43Å; G312-Y315 PolarHBondContact O-N 3.02Å; G312-Y315 VanDerWaalsContact O-N 3.16Å; S313-Y315 VanDerWaalsContact C-N 3.31Å
316I98.6Very high89.9Confident8 Ų844.8 Ų44.84%0.04126%0.255CS..EExtended strand (participates in β ladder)trans-139.4145.6162-173.5167.8000109.3I301 L303 A318 D405 F406 M409I301-I316 HydrophobicContact CB-CG2 4.05Å; I301-I316 HydrophobicContact CG2-CG2 4.28Å; L303-I316 HydrophobicContact CD1-CB 4.09Å; L303-I316 HydrophobicContact CD1-CG2 4.36Å; L303-I316 HydrophobicContact CD2-CB 4.44Å; L303-I316 HydrophobicContact CD2-CG2 3.89Å; L303-I316 HydrophobicContact CG-CB 4.22Å; L303-I316 HydrophobicContact CG-CG2 3.94Å; I316-A318 HydrophobicContact CG2-CB 4.17Å; I316-A318 PolarHBondContact O-N 3.14Å; I316-D405 HydrophobicContact CD1-CB 4.17Å; I316-F406 HydrophobicContact CD1-CB 4.48Å; I316-M409 HydrophobicContact CD1-CB 4.17Å; I316-M409 HydrophobicContact CD1-CE 4.23Å; I316-M409 HydrophobicContact CD1-SD 3.92Å; I316-M409 HydrophobicContact CG2-SD 4.22Å
317N98.7Very high87.6Confident2 Ų249.8 Ų49.81%0.01127%0.274CS..EExtended strand (participates in β ladder)trans-77.575.5175.5-170.3-35.4000111.3N288 I293 T395 Q396 R571N288-N317 PolarHBondContact OD1-ND2 3.44Å; I293-N317 PolarHBondContact O-ND2 3.05Å; N317-T395 PolarHBondContact O-OG1 3.4Å; N317-Q396 HydrophobicContact CB-CG 4.13Å; N317-Q396 PolarHBondContact ND2-OE1 2.9Å; N317-Q396 PolarHBondContact O-N 3.46Å; N317-R571 PolarHBondContact OD1-NH1 3.33Å; N317-R571 PolarHBondContact OD1-NH2 2.97Å
318A98.8Very high85.2Confident0 Ų052.9 Ų52.90%028%0.283CS..EExtended strand (participates in β ladder)trans-145.4148.1178.100000110.8R300 I301 I316 I393 S394 M409R300-A318 VanDerWaalsContact CA-O 3.3Å; R300-A318 WeakPolarHBondContact CA-O 3.38Å; I301-A318 HydrophobicContact CB-CB 4.26Å; I301-A318 HydrophobicContact CG1-CB 3.95Å; I301-A318 PolarHBondContact N-O 3.19Å; I316-A318 HydrophobicContact CG2-CB 4.17Å; I316-A318 PolarHBondContact O-N 3.14Å; A318-I393 HydrophobicContact CB-CG2 3.93Å; A318-S394 CarbonylContact C-O 3.56Å; A318-S394 VanDerWaalsContact CA-O 3.3Å; A318-S394 WeakPolarHBondContact CA-O 3.3Å; A318-M409 HydrophobicContact CB-SD 3.66Å
319N98.6Very high82.5Confident0 Ų051 Ų510%027%0.273CS..EExtended strand (participates in β ladder)trans-120.8139.1170-66.795.2000110.4P295 F296 T299 R300 I393 S394 R571P295-N319 WeakPolarHBondContact CA-OD1 3.39Å; P295-N319 WeakPolarHBondContact CB-OD1 3.29Å; F296-N319 PolarHBondContact N-ND2 3.49Å; F296-N319 VanDerWaalsContact N-ND2 3.14Å; F296-N319 PolarHBondContact O-ND2 3.27Å; T299-N319 CarbonylContact O-C 3.54Å; T299-N319 VanDerWaalsContact O-CA 3.24Å; T299-N319 WeakPolarHBondContact O-CA 3.24Å; T299-N319 PolarHBondContact O-ND2 2.98Å; T299-N319 PolarHBondContact OG1-ND2 3.34Å; R300-N319 PolarHBondContact N-ND2 2.91Å; N319-I393 WeakPolarHBondContact O-CA 3.35Å; N319-S394 PolarHBondContact N-O 3.41Å; N319-S394 PolarHBondContact O-N 2.9Å; N319-R571 HydrophobicContact CB-CB 4.07Å; N319-R571 HydrophobicContact CB-CG 4.36Å; N319-R571 WeakPolarHBondContact OD1-CG 3.38Å; N319-R571 PolarHBondContact OD1-NH1 2.84Å
320L98.3Very high79.6Confident41 Ų4149.1 Ų49.122%0.21527%0.269CS..EExtended strand (participates in β ladder)trans-67.9134.6161-173.464.6000108.7T299 I301 E322 S391 I393 P524T299-L320 PolarHBondContact O-N 3.11Å; I301-L320 HydrophobicContact CD1-CB 3.8Å; I301-L320 HydrophobicContact CD1-CD1 4.46Å; L320-E322 HydrophobicContact CD1-CG 4.2Å; L320-E322 HydrophobicContact CD2-CG 3.95Å; L320-E322 HydrophobicContact CG-CG 3.89Å; L320-S391 WeakPolarHBondContact CD1-OG 3.08Å; L320-I393 HydrophobicContact CD1-CG1 4.26Å; L320-P524 HydrophobicContact CD1-CB 4.48Å; L320-P524 HydrophobicContact CD1-CG 4.26Å
321I97.1Very high76.5Confident0 Ų053 Ų530%028%0.284CS..EExtended strand (participates in β ladder)trans-122.6105.3172.5-61.1178.8000106.8S391 Y392 I540 L567 Q570 M574I321-S391 CarbonylContact O-C 3.56Å; I321-S391 WeakPolarHBondContact O-CA 3.49Å; I321-Y392 HydrophobicContact CG2-CD2 4.35Å; I321-Y392 PolarHBondContact N-O 3.01Å; I321-Y392 PolarHBondContact O-N 3.05Å; I321-I540 HydrophobicContact CD1-CD1 3.91Å; I321-L567 HydrophobicContact CD1-CD2 4.34Å; I321-L567 HydrophobicContact CG2-CD2 3.62Å; I321-Q570 HydrophobicContact CG1-CB 4.17Å; I321-M574 HydrophobicContact CD1-CE 3.66Å
322E92.8Very high73.5Confident97 Ų9754.1 Ų54.145%0.45329%0.29SS..EExtended strand (participates in β ladder)trans-107.5130.8177.4-79.2-176.614500110.7L320 Q570L320-E322 HydrophobicContact CD1-CG 4.2Å; L320-E322 HydrophobicContact CD2-CG 3.95Å; L320-E322 HydrophobicContact CG-CG 3.89Å; E322-Q570 PolarHBondContact O-NE2 3.04Å; E322-Q570 PolarHBondContact O-OE1 2.82Å
323V87.1Confident70.6Confident0 Ų064.7 Ų64.70%033%0.33CS..EExtended strand (participates in β ladder)trans-113.5103.2165.4179.50000105.6F385 K389 R390 L544 M566V323-F385 HydrophobicContact CG1-CB 3.45Å; V323-F385 VanDerWaalsContact CG1-CB 3.45Å; V323-F385 HydrophobicContact CG1-CD1 3.98Å; V323-F385 HydrophobicContact CG1-CD2 3.84Å; V323-F385 HydrophobicContact CG1-CG 3.48Å; V323-F385 VanDerWaalsContact CG1-CG 3.48Å; V323-K389 CarbonylContact O-C 3.57Å; V323-K389 VanDerWaalsContact O-CA 3.28Å; V323-K389 WeakPolarHBondContact O-CA 3.25Å; V323-R390 PolarHBondContact N-O 2.7Å; V323-R390 PolarHBondContact O-N 2.77Å; V323-L544 HydrophobicContact CB-CD2 3.97Å; V323-L544 HydrophobicContact CG1-CD2 4.3Å; V323-L544 HydrophobicContact CG2-CD1 3.78Å; V323-L544 HydrophobicContact CG2-CD2 3.63Å; V323-L544 HydrophobicContact CG2-CG 4.37Å; V323-M566 HydrophobicContact CG2-CE 3.61Å; V323-M566 HydrophobicContact CG2-SD 3.96Å
324S73.8Confident67.6Low63 Ų6367.5 Ų67.544%0.44135%0.347SS..EExtended strand (participates in β ladder)trans-131.1118.7169.5710000108.8
325Y59.5Low64.5Low62 Ų6269.7 Ų69.724%0.24336%0.359CS..  trans-100.6109.3165-173.5-93.1000107.1E327 V378 N386Y325-E327 HydrophobicContact CD1-CG 4.19Å; Y325-E327 HydrophobicContact CE1-CB 4.29Å; Y325-E327 HydrophobicContact CE1-CG 3.59Å; Y325-V378 HydrophobicContact CE2-CG1 4.23Å; Y325-N386 HydrophobicContact CD1-CB 3.93Å; Y325-N386 WeakPolarHBondContact CD1-OD1 3.42Å; Y325-N386 HydrophobicContact CE1-CB 3.98Å; Y325-N386 WeakPolarHBondContact CE1-OD1 3.37Å; Y325-N386 HydrophobicContact CG-CB 4.34Å
326Q46.7Very low61.5Low135 Ų13574.3 Ų74.363%0.63139%0.387SS*.  trans-82.7118.6158.9-70.6-176.8-12.300105.8F328Q326-F328 PolarHBondContact O-N 3.09Å
327E42.4Very low58.5Low124 Ų12480.5 Ų80.558%0.57942%0.415SS*.  trans-56.3101151.8-82.3-179.4171.200104Y325 S329 N386Y325-E327 HydrophobicContact CD1-CG 4.19Å; Y325-E327 HydrophobicContact CE1-CB 4.29Å; Y325-E327 HydrophobicContact CE1-CG 3.59Å; E327-S329 PolarHBondContact O-N 3.03Å; E327-N386 PolarHBondContact OE1-ND2 2.88Å
328F39.5Very low55.7Low106 Ų10687.5 Ų87.547%0.46545%0.448SS..  trans-61.986.5145.1-65-75.8000102.7Q326 C330 F376 V378Q326-F328 PolarHBondContact O-N 3.09Å; F328-C330 VanDerWaalsContact C-N 3.31Å; F328-C330 PolarHBondContact O-N 2.9Å; F328-F376 AromaticContact CE1-CD1 3.68Å; F328-F376 HydrophobicContact CE1-CD1 3.68Å; F328-F376 AromaticContact CE1-CE1 3.75Å; F328-F376 HydrophobicContact CE1-CE1 3.75Å; F328-F376 HydrophobicContact CE2-CD1 4.05Å; F328-F376 AromaticContact CZ-CD1 3.39Å; F328-F376 HydrophobicContact CZ-CD1 3.39Å; F328-F376 AromaticContact CZ-CE1 3.67Å; F328-F376 HydrophobicContact CZ-CE1 3.67Å; F328-V378 HydrophobicContact CD2-CG2 4.45Å
329S32.5Very low53Low91 Ų9194.2 Ų94.264%0.63648%0.483SS*.  trans-37114.1151.1157.50000102.7E327 M331E327-S329 PolarHBondContact O-N 3.03Å; S329-M331 VanDerWaalsContact C-N 3.31Å; S329-M331 PolarHBondContact O-N 3.38Å
330C30.9Very low50.1Low90 Ų9099.8 Ų99.861%0.60851%0.507SS*.  trans-31.7107171.6173.50000105.2F328 T332F328-C330 VanDerWaalsContact C-N 3.31Å; F328-C330 PolarHBondContact O-N 2.9Å; C330-T332 WeakPolarHBondContact O-CA 3.35Å; C330-T332 PolarHBondContact O-N 3.22Å
331M29.4Very low47.4Very low151 Ų151102.3 Ų102.374%0.74452%0.52SS*.  trans-59.497.2170.6-96.6-80.8176.100100.7S329 Y333 V334S329-M331 VanDerWaalsContact C-N 3.31Å; S329-M331 PolarHBondContact O-N 3.38Å; M331-Y333 PolarHBondContact O-N 3.39Å; M331-V334 HydrophobicContact SD-CB 4.34Å; M331-V334 HydrophobicContact SD-CG2 3.9Å
332T31.8Very low44.7Very low105 Ų105107.4 Ų107.464%0.64455%0.553SS**  trans-61.985.4-165.334.30000106.3C330 V334C330-T332 WeakPolarHBondContact O-CA 3.35Å; C330-T332 PolarHBondContact O-N 3.22Å; T332-V334 WeakPolarHBondContact O-CA 3.49Å; T332-V334 PolarHBondContact O-N 3.42Å
333Y34.3Very low42.2Very low224 Ų224112.5 Ų112.588%0.87857%0.57SS**  trans28.751.3-175.9-91.6-97.7000110.8M331 N335M331-Y333 PolarHBondContact O-N 3.39Å; Y333-N335 PolarHBondContact O-N 2.88Å
334V32.8Very low39.9Very low80 Ų80120 Ų12049%0.48560%0.603SS.*  trans-69.7104.3-176.4176.40000103M331 T332 V336M331-V334 HydrophobicContact SD-CB 4.34Å; M331-V334 HydrophobicContact SD-CG2 3.9Å; T332-V334 WeakPolarHBondContact O-CA 3.49Å; T332-V334 PolarHBondContact O-N 3.42Å; V334-V336 PolarHBondContact O-N 3.45Å
335N32.2Very low38.2Very low85 Ų85120.6 Ų120.646%0.45562%0.619SS.*  trans-32.6100.6-163.7-149.5-19.8000110.2Y333 Q337 H338Y333-N335 PolarHBondContact O-N 2.88Å; N335-Q337 PolarHBondContact O-N 3.24Å; N335-Q337 WeakPolarHBondContact OD1-CB 3.44Å; N335-Q337 WeakPolarHBondContact OD1-CG 3.41Å; N335-Q337 PolarHBondContact OD1-OE1 3.36Å; N335-H338 PolarHBondContact O-N 2.96Å
336V35.4Very low37.1Very low97 Ų97121.3 Ų121.359%0.58863%0.629SS**Hα-helixtrans-57.2-14.7-179.3-177.30000110.3V334 H338 F340V334-V336 PolarHBondContact O-N 3.45Å; V336-H338 VanDerWaalsContact C-N 3.33Å; V336-H338 PolarHBondContact O-N 3.36Å; V336-F340 HydrophobicContact CG1-CD2 3.93Å; V336-F340 HydrophobicContact CG1-CE2 3.7Å; V336-F340 VanDerWaalsContact O-CD2 3.29Å; V336-F340 WeakPolarHBondContact O-CD2 3.13Å
337Q35.8Very low36.7Very low138 Ų138117 Ų11765%0.64562%0.622SS**Hα-helixtrans-60.7-32.2169.7-63.4-176.9-25.100114.3N335N335-Q337 PolarHBondContact O-N 3.24Å; N335-Q337 WeakPolarHBondContact OD1-CB 3.44Å; N335-Q337 WeakPolarHBondContact OD1-CG 3.41Å; N335-Q337 PolarHBondContact OD1-OE1 3.36Å
338H39.7Very low37Very low149 Ų149115.1 Ų115.169%0.6963%0.627SS**Hα-helixtrans-87.2-21-172.4-103.3-78000115.2N335 V336N335-H338 PolarHBondContact O-N 2.96Å; V336-H338 VanDerWaalsContact C-N 3.33Å; V336-H338 PolarHBondContact O-N 3.36Å
339L41.9Very low37.1Very low141 Ų141118.6 Ų118.674%0.73865%0.645SS**Hα-helixtrans-82.5-15.1176.9-90.6152.1000113.1
340F39.3Very low37.6Very low116 Ų116119.1 Ų119.151%0.50964%0.641SS.*Hα-helixtrans-95.7-19.3-172.3-88.9-93.4000115.2V336V336-F340 HydrophobicContact CG1-CD2 3.93Å; V336-F340 HydrophobicContact CG1-CE2 3.7Å; V336-F340 VanDerWaalsContact O-CD2 3.29Å; V336-F340 WeakPolarHBondContact O-CD2 3.13Å
341L40.7Very low38.2Very low94 Ų94121.1 Ų121.149%0.49264%0.644SS.*SBendtrans-78.3-34.3-171.5-69.7170.9000115.8
342P40Very low38.7Very low107 Ų107120.8 Ų120.870%0.69565%0.646SS**SBendtrans-81-19.1-177-13.328.9000114.6
343Y40Very low38.8Very low204 Ų204122.8 Ų122.880%0.865%0.652SS**SBendtrans-87.1-16.2-166.6-133.6-90.8000114.6
344F40.3Very low38.9Very low158 Ų158115.9 Ų115.969%0.69364%0.642SS**SBendtrans-118.85.4-179.5-74.9-77.6000114.4V346F344-V346 HydrophobicContact CB-CG2 4.13Å; F344-V346 VanDerWaalsContact O-CG2 3.25Å; F344-V346 WeakPolarHBondContact O-CG2 3.23Å; F344-V346 PolarHBondContact O-N 3.2Å
345G37.4Very low39Very low75 Ų75122 Ų12277%0.77366%0.657SS**  trans59.122.5171.200000114.7
346V36.9Very low39.2Very low77 Ų77128.5 Ų128.547%0.46768%0.677SS.*  trans-96.7114.7179.1-162.60000107.6F344 D350F344-V346 HydrophobicContact CB-CG2 4.13Å; F344-V346 VanDerWaalsContact O-CG2 3.25Å; F344-V346 WeakPolarHBondContact O-CG2 3.23Å; F344-V346 PolarHBondContact O-N 3.2Å; V346-D350 HydrophobicContact CG1-CB 3.75Å
347G38.6Very low39.1Very low46 Ų46129.3 Ų129.347%0.47469%0.686SS.*  trans-60.8149.8174.400000110.5E349 D350G347-E349 PolarHBondContact O-N 3.22Å; G347-D350 PolarHBondContact O-N 3.48Å
348A47Very low39Very low83 Ų83125.6 Ų125.669%0.68669%0.685SS**THydrogen-bonded Turntrans-57.4-12.1-177.900000114.4
349E43.3Very low39.1Very low179 Ų179125.4 Ų125.484%0.83669%0.689SS**THydrogen-bonded Turntrans-84.8-17.4-177.4-61.8-171.8168.800114.1G347 L351G347-E349 PolarHBondContact O-N 3.22Å; E349-L351 PolarHBondContact O-N 2.86Å
350D42.1Very low38.8Very low103 Ų103124.8 Ų124.855%0.55169%0.686SS**G310 helixtrans-86.7-3.4-174.6-73.5-38.9000114.9V346 G347 N352 N353V346-D350 HydrophobicContact CG1-CB 3.75Å; G347-D350 PolarHBondContact O-N 3.48Å; D350-N352 PolarHBondContact O-N 3.03Å; D350-N353 PolarHBondContact O-N 3.37Å
351L43.7Very low38.8Very low131 Ų131123.5 Ų123.569%0.68669%0.687SS**G310 helixtrans-68.8-15.7179.8-86.6161.4000114E349E349-L351 PolarHBondContact O-N 2.86Å
352N39.2Very low38.8Very low145 Ų145127.1 Ų127.178%0.77570%0.699SS**G310 helixtrans-79.9-14.5179.4-83.2-21.8000114.3D350D350-N352 PolarHBondContact O-N 3.03Å
353N35.3Very low38.8Very low147 Ų147128 Ų12879%0.78670%0.695SS**SBendtrans-111.71.6-175.6-81.6-19.1000115.3D350 Y355D350-N353 PolarHBondContact O-N 3.37Å; N353-Y355 PolarHBondContact O-N 3.24Å; N353-Y355 VanDerWaalsContact O-N 3.1Å
354A36.4Very low38.8Very low79 Ų79125.2 Ų125.265%0.65369%0.687SS**THydrogen-bonded Turntrans-85.636.5-179.600000114.3Y356A354-Y356 VanDerWaalsContact C-N 3.35Å
355Y34.5Very low39Very low208 Ų208123 Ų12382%0.81668%0.682SS**THydrogen-bonded Turntrans-88.51.4168.6-90.3-79.9000113.8N353N353-Y355 PolarHBondContact O-N 3.24Å; N353-Y355 VanDerWaalsContact O-N 3.1Å
356Y36.6Very low39.5Very low221 Ų221121.9 Ų121.987%0.86766%0.662SS**SBendtrans-134.571179.6-73-83.6000112.4A354A354-Y356 VanDerWaalsContact C-N 3.35Å
357C31.8Very low40.1Very low114 Ų114123.1 Ų123.177%0.7767%0.665SS**  trans-154.9109.6151-156.90000109.6
358G34.3Very low40.2Very low61 Ų61130.2 Ų130.263%0.62968%0.678SS**  trans-71.9145.8-16800000115.7L360G358-L360 VanDerWaalsContact C-N 3.28Å; G358-L360 PolarHBondContact O-N 3.4Å
359D42.3Very low40.2Very low144 Ų144131.2 Ų131.277%0.7767%0.671SS**SBendtrans51.4-24149.2-64.6-24.3000122.4
360L35.6Very low40.4Very low128 Ų128127 Ų12767%0.6765%0.653SS**Hα-helixtrans-82.9-31.4-177.1-121.180000113.7G358 F364G358-L360 VanDerWaalsContact C-N 3.28Å; G358-L360 PolarHBondContact O-N 3.4Å; L360-F364 WeakPolarHBondContact O-CD2 3.22Å
361T39.7Very low40.4Very low89 Ų89125.4 Ų125.455%0.54665%0.65SS.*Hα-helixtrans-79.2-32.9-175.445.30000113.3Q363 F364 L365T361-Q363 VanDerWaalsContact C-N 3.35Å; T361-Q363 PolarHBondContact O-N 3.19Å; T361-F364 PolarHBondContact O-N 3.3Å; T361-L365 WeakPolarHBondContact O-CD1 3.41Å; T361-L365 PolarHBondContact O-N 3.08Å
362F39.5Very low40.5Very low170 Ų170125.7 Ų125.775%0.74665%0.646SS**Hα-helixtrans-68.5-31.3178.6-104.8-88.6000113.2S366F362-S366 WeakPolarHBondContact O-CB 3.4Å; F362-S366 PolarHBondContact O-N 2.83Å; F362-S366 PolarHBondContact O-OG 3.45Å
363Q40.4Very low40.7Very low127 Ų127123.7 Ų123.759%0.59363%0.634SS**Hα-helixtrans-70.4-35.6-179.7-131.1172.6-3.500112.1T361 S366 L367T361-Q363 VanDerWaalsContact C-N 3.35Å; T361-Q363 PolarHBondContact O-N 3.19Å; Q363-S366 PolarHBondContact O-OG 3.09Å; Q363-L367 WeakPolarHBondContact O-CD1 3.49Å; Q363-L367 PolarHBondContact O-N 3.04Å
364F39.6Very low41Very low144 Ų144124.1 Ų124.163%0.63263%0.629SS**Hα-helixtrans-77.1-34.4175.5-77-79.5000113.4L360 T361 R368L360-F364 WeakPolarHBondContact O-CD2 3.22Å; T361-F364 PolarHBondContact O-N 3.3Å; F364-R368 PolarHBondContact O-N 3.49Å; F364-R368 VanDerWaalsContact O-N 3.14Å
365L44Very low41.2Very low112 Ų112129.1 Ų129.159%0.58664%0.636SS**Hα-helixtrans-65.5-42.8173.8-101.796.5000112T361 L369T361-L365 WeakPolarHBondContact O-CD1 3.41Å; T361-L365 PolarHBondContact O-N 3.08Å; L365-L369 VanDerWaalsContact O-CB 3.31Å; L365-L369 WeakPolarHBondContact O-CB 3.43Å; L365-L369 PolarHBondContact O-N 2.7Å
366S49.6Very low41.4Very low51 Ų51123.9 Ų123.936%0.35762%0.618SS.*Hα-helixtrans-66.2-45.6179.158.50000112F362 Q363 R368 L369 I370F362-S366 WeakPolarHBondContact O-CB 3.4Å; F362-S366 PolarHBondContact O-N 2.83Å; F362-S366 PolarHBondContact O-OG 3.45Å; Q363-S366 PolarHBondContact O-OG 3.09Å; S366-R368 PolarHBondContact O-N 3.17Å; S366-L369 PolarHBondContact O-N 3.46Å; S366-I370 VanDerWaalsContact O-CB 3.25Å; S366-I370 WeakPolarHBondContact O-CB 3.47Å; S366-I370 VanDerWaalsContact O-CD1 3.3Å; S366-I370 WeakPolarHBondContact O-CD1 3.27Å; S366-I370 WeakPolarHBondContact O-CG1 3.33Å; S366-I370 PolarHBondContact O-N 2.99Å
367L47.7Very low41.6Very low103 Ų103116.1 Ų116.154%0.53960%0.596SS.*Hα-helixtrans-64.2-38.9178-101.1124.6000112.9Q363 C371Q363-L367 WeakPolarHBondContact O-CD1 3.49Å; Q363-L367 PolarHBondContact O-N 3.04Å; L367-C371 VanDerWaalsContact O-CB 3.26Å; L367-C371 WeakPolarHBondContact O-CB 3.39Å; L367-C371 PolarHBondContact O-N 3.43Å; L367-C371 PolarHBondContact O-SG 2.97Å
368R42.4Very low42.2Very low196 Ų196113.6 Ų113.674%0.7458%0.577SS**Hα-helixtrans-73.6-37.4178.3-74.3-165177.6-176.32.2112.7F364 S366 C371 F372F364-R368 PolarHBondContact O-N 3.49Å; F364-R368 VanDerWaalsContact O-N 3.14Å; S366-R368 PolarHBondContact O-N 3.17Å; R368-C371 PolarHBondContact O-N 2.82Å; R368-F372 VanDerWaalsContact O-CB 3.29Å; R368-F372 WeakPolarHBondContact O-CB 3.26Å; R368-F372 PolarHBondContact O-N 3.03Å
369L47.1Very low43Very low104 Ų104115.3 Ų115.355%0.54557%0.571SS.*Hα-helixtrans-67-41.2174.1-164.877000111.2L365 S366 F372 I373L365-L369 VanDerWaalsContact O-CB 3.31Å; L365-L369 WeakPolarHBondContact O-CB 3.43Å; L365-L369 PolarHBondContact O-N 2.7Å; S366-L369 PolarHBondContact O-N 3.46Å; L369-F372 PolarHBondContact O-N 3.27Å; L369-I373 HydrophobicContact CD2-CD1 4.47Å; L369-I373 HydrophobicContact CG-CD1 4.12Å; L369-I373 WeakPolarHBondContact O-CB 3.39Å; L369-I373 VanDerWaalsContact O-CG1 3.26Å; L369-I373 WeakPolarHBondContact O-CG1 3.34Å; L369-I373 PolarHBondContact O-N 2.87Å
370I47.5Very low43.6Very low89 Ų89112.8 Ų112.846%0.45656%0.563SS.*Hα-helixtrans-62.2-47.7173.7-69.2164.3000109.8S366 F372 I373 F374S366-I370 VanDerWaalsContact O-CB 3.25Å; S366-I370 WeakPolarHBondContact O-CB 3.47Å; S366-I370 VanDerWaalsContact O-CD1 3.3Å; S366-I370 WeakPolarHBondContact O-CD1 3.27Å; S366-I370 WeakPolarHBondContact O-CG1 3.33Å; S366-I370 PolarHBondContact O-N 2.99Å; I370-F372 VanDerWaalsContact C-N 3.3Å; I370-F372 PolarHBondContact O-N 3.23Å; I370-I373 PolarHBondContact O-N 3.24Å; I370-F374 HydrophobicContact CG2-CD2 3.7Å; I370-F374 HydrophobicContact CG2-CE2 3.98Å; I370-F374 WeakPolarHBondContact O-CB 3.31Å; I370-F374 WeakPolarHBondContact O-CD2 3.49Å; I370-F374 PolarHBondContact O-N 3.32Å
371C42.2Very low44.6Very low71 Ų71107.6 Ų107.648%0.4854%0.535SS..Hα-helixtrans-61.6-37.7175.5-760000112.2L367 R368 F374 F375L367-C371 VanDerWaalsContact O-CB 3.26Å; L367-C371 WeakPolarHBondContact O-CB 3.39Å; L367-C371 PolarHBondContact O-N 3.43Å; L367-C371 PolarHBondContact O-SG 2.97Å; R368-C371 PolarHBondContact O-N 2.82Å; C371-F374 PolarHBondContact O-N 2.87Å; C371-F375 WeakPolarHBondContact O-CB 3.17Å; C371-F375 PolarHBondContact O-N 2.69Å
372F43.9Very low45.7Very low137 Ų137105.1 Ų105.160%0.60152%0.517SS*.Hα-helixtrans-67.6-44177-147.6-95.3000111R368 L369 I370 F374 F375 F376R368-F372 VanDerWaalsContact O-CB 3.29Å; R368-F372 WeakPolarHBondContact O-CB 3.26Å; R368-F372 PolarHBondContact O-N 3.03Å; L369-F372 PolarHBondContact O-N 3.27Å; I370-F372 VanDerWaalsContact C-N 3.3Å; I370-F372 PolarHBondContact O-N 3.23Å; F372-F374 VanDerWaalsContact C-N 3.34Å; F372-F374 PolarHBondContact O-N 2.91Å; F372-F375 PolarHBondContact O-N 2.88Å; F372-F376 AromaticContact CD1-CD2 3.73Å; F372-F376 HydrophobicContact CD1-CD2 3.73Å; F372-F376 AromaticContact CD1-CE2 3.94Å; F372-F376 HydrophobicContact CD1-CE2 3.94Å; F372-F376 HydrophobicContact CD2-CE2 4.42Å; F372-F376 AromaticContact CE1-CD2 3.69Å; F372-F376 HydrophobicContact CE1-CD2 3.69Å; F372-F376 AromaticContact CE1-CE2 3.48Å; F372-F376 HydrophobicContact CE1-CE2 3.48Å; F372-F376 VanDerWaalsContact CE1-CE2 3.48Å; F372-F376 HydrophobicContact CE1-CZ 4.47Å; F372-F376 HydrophobicContact CE2-CE2 4.03Å; F372-F376 HydrophobicContact CG-CD2 4.27Å; F372-F376 HydrophobicContact CG-CE2 4.39Å; F372-F376 HydrophobicContact CZ-CD2 4.2Å; F372-F376 AromaticContact CZ-CE2 3.54Å; F372-F376 HydrophobicContact CZ-CE2 3.54Å; F372-F376 HydrophobicContact CZ-CZ 4.39Å; F372-F376 VanDerWaalsContact O-CD2 3.31Å; F372-F376 WeakPolarHBondContact O-CD2 3.37Å; F372-F376 PolarHBondContact O-N 3.15Å; F372-F376 VanDerWaalsContact O-N 3.1Å
373I44.3Very low46.7Very low102 Ų102102 Ų10252%0.52350%0.504SS..Hα-helixtrans-64.7-38174.5-66.8167.3000110.8L369 I370 S377L369-I373 HydrophobicContact CD2-CD1 4.47Å; L369-I373 HydrophobicContact CG-CD1 4.12Å; L369-I373 WeakPolarHBondContact O-CB 3.39Å; L369-I373 VanDerWaalsContact O-CG1 3.26Å; L369-I373 WeakPolarHBondContact O-CG1 3.34Å; L369-I373 PolarHBondContact O-N 2.87Å; I370-I373 PolarHBondContact O-N 3.24Å; I373-S377 WeakPolarHBondContact O-CB 3.37Å; I373-S377 PolarHBondContact O-N 3.11Å; I373-S377 PolarHBondContact O-OG 3.3Å
374F41.8Very low48.2Very low156 Ų15696.8 Ų96.868%0.68448%0.48SS*.Hα-helixtrans-72.4-33.3176.4-94.1-86.1000113.5I370 C371 F372 F376 S377I370-F374 HydrophobicContact CG2-CD2 3.7Å; I370-F374 HydrophobicContact CG2-CE2 3.98Å; I370-F374 WeakPolarHBondContact O-CB 3.31Å; I370-F374 WeakPolarHBondContact O-CD2 3.49Å; I370-F374 PolarHBondContact O-N 3.32Å; C371-F374 PolarHBondContact O-N 2.87Å; F372-F374 VanDerWaalsContact C-N 3.34Å; F372-F374 PolarHBondContact O-N 2.91Å; F374-F376 VanDerWaalsContact C-N 3.33Å; F374-S377 VanDerWaalsContact CA-OG 3.26Å; F374-S377 WeakPolarHBondContact CA-OG 3.46Å; F374-S377 PolarHBondContact O-OG 2.85Å
375F40.8Very low49.9Very low185 Ų18590 Ų9081%0.81145%0.451SS*.Hα-helixtrans-72.2-28.9175.7-121.6-93.4000112.3C371 F372C371-F375 WeakPolarHBondContact O-CB 3.17Å; C371-F375 PolarHBondContact O-N 2.69Å; F372-F375 PolarHBondContact O-N 2.88Å
376F37.5Very low51Low98 Ų9886.1 Ų86.143%0.4343%0.43SS..Hα-helixtrans-103.2-7.8-179.4-76.3-76.1000114.5F328 F372 F374 V378F328-F376 AromaticContact CE1-CD1 3.68Å; F328-F376 HydrophobicContact CE1-CD1 3.68Å; F328-F376 AromaticContact CE1-CE1 3.75Å; F328-F376 HydrophobicContact CE1-CE1 3.75Å; F328-F376 HydrophobicContact CE2-CD1 4.05Å; F328-F376 AromaticContact CZ-CD1 3.39Å; F328-F376 HydrophobicContact CZ-CD1 3.39Å; F328-F376 AromaticContact CZ-CE1 3.67Å; F328-F376 HydrophobicContact CZ-CE1 3.67Å; F372-F376 AromaticContact CD1-CD2 3.73Å; F372-F376 HydrophobicContact CD1-CD2 3.73Å; F372-F376 AromaticContact CD1-CE2 3.94Å; F372-F376 HydrophobicContact CD1-CE2 3.94Å; F372-F376 HydrophobicContact CD2-CE2 4.42Å; F372-F376 AromaticContact CE1-CD2 3.69Å; F372-F376 HydrophobicContact CE1-CD2 3.69Å; F372-F376 AromaticContact CE1-CE2 3.48Å; F372-F376 HydrophobicContact CE1-CE2 3.48Å; F372-F376 VanDerWaalsContact CE1-CE2 3.48Å; F372-F376 HydrophobicContact CE1-CZ 4.47Å; F372-F376 HydrophobicContact CE2-CE2 4.03Å; F372-F376 HydrophobicContact CG-CD2 4.27Å; F372-F376 HydrophobicContact CG-CE2 4.39Å; F372-F376 HydrophobicContact CZ-CD2 4.2Å; F372-F376 AromaticContact CZ-CE2 3.54Å; F372-F376 HydrophobicContact CZ-CE2 3.54Å; F372-F376 HydrophobicContact CZ-CZ 4.39Å; F372-F376 VanDerWaalsContact O-CD2 3.31Å; F372-F376 WeakPolarHBondContact O-CD2 3.37Å; F372-F376 PolarHBondContact O-N 3.15Å; F372-F376 VanDerWaalsContact O-N 3.1Å; F374-F376 VanDerWaalsContact C-N 3.33Å; F376-V378 PolarHBondContact O-N 3.42Å
377S41.2Very low52.1Low57 Ų5784.9 Ų84.940%0.39943%0.426SS..SBendtrans-70.8105.3167.925.80000107.4I373 F374 L379I373-S377 WeakPolarHBondContact O-CB 3.37Å; I373-S377 PolarHBondContact O-N 3.11Å; I373-S377 PolarHBondContact O-OG 3.3Å; F374-S377 VanDerWaalsContact CA-OG 3.26Å; F374-S377 WeakPolarHBondContact CA-OG 3.46Å; F374-S377 PolarHBondContact O-OG 2.85Å; S377-L379 PolarHBondContact O-N 3.14Å; S377-L379 VanDerWaalsContact O-N 3.09Å
378V45.5Very low53.7Low62 Ų6280.3 Ų80.338%0.37640%0.402SS..  trans-44.4119.4171.8177.90000108Y325 F328 F376 F382Y325-V378 HydrophobicContact CE2-CG1 4.23Å; F328-V378 HydrophobicContact CD2-CG2 4.45Å; F376-V378 PolarHBondContact O-N 3.42Å; V378-F382 HydrophobicContact CG1-CB 4.18Å
379L51.5Low55.8Low96 Ų9679.3 Ų79.350%0.50340%0.403SS..  trans-54.7127.8172.6-69.5176.4000106.9S377 E381 F382S377-L379 PolarHBondContact O-N 3.14Å; S377-L379 VanDerWaalsContact O-N 3.09Å; L379-E381 PolarHBondContact O-N 3.16Å; L379-F382 HydrophobicContact CB-CD2 3.91Å; L379-F382 HydrophobicContact CB-CE2 4.18Å; L379-F382 HydrophobicContact CD1-CE2 4.15Å; L379-F382 PolarHBondContact O-N 3.15Å
380P54Low57.9Low92 Ų9275.3 Ų75.360%0.59738%0.381SS*.G310 helixtrans-48.9-33.6-173.1-29.233000112.7F382 E383 Q562P380-F382 PolarHBondContact O-N 3.28Å; P380-F382 VanDerWaalsContact O-N 3.11Å; P380-E383 WeakPolarHBondContact O-CB 3.48Å; P380-E383 PolarHBondContact O-N 2.97Å; P380-E383 VanDerWaalsContact O-N 3.15Å; P380-Q562 VanDerWaalsContact C-NE2 3.31Å; P380-Q562 PolarHBondContact O-NE2 2.85Å
381E57.1Low60.2Low19 Ų1971.9 Ų71.99%0.08937%0.365CS..G310 helixtrans-50.8-26.8176.9-62.8168.8177.400115.5H272 L379 Q565 M566H272-E381 IonicContact CE1-OE1 3.81Å; H272-E381 PolarHBondContact CE1-OE1 3.05Å; L379-E381 PolarHBondContact O-N 3.16Å; E381-Q565 HydrophobicContact CG-CG 4.41Å; E381-Q565 PolarHBondContact OE1-NE2 2.79Å; E381-M566 HydrophobicContact CB-CB 4.25Å
382F61.5Low62.9Low37 Ų3768.7 Ų68.716%0.16234%0.342CS..G310 helixtrans-95.2-13.2-178.2-68.5-93.4000114.4V378 L379 P380 I384 F385 M566V378-F382 HydrophobicContact CG1-CB 4.18Å; L379-F382 HydrophobicContact CB-CD2 3.91Å; L379-F382 HydrophobicContact CB-CE2 4.18Å; L379-F382 HydrophobicContact CD1-CE2 4.15Å; L379-F382 PolarHBondContact O-N 3.15Å; P380-F382 PolarHBondContact O-N 3.28Å; P380-F382 VanDerWaalsContact O-N 3.11Å; F382-I384 PolarHBondContact O-N 3.47Å; F382-I384 VanDerWaalsContact O-N 3.16Å; F382-F385 PolarHBondContact O-N 3.12Å; F382-M566 HydrophobicContact CD1-CG 4.25Å; F382-M566 HydrophobicContact CE1-CG 3.86Å; F382-M566 HydrophobicContact CE1-SD 4.34Å; F382-M566 HydrophobicContact CE2-CG 4.39Å; F382-M566 HydrophobicContact CZ-CG 3.95Å
383E62Low65.5Low103 Ų10362.1 Ų62.148%0.48131%0.314SS..G310 helixtrans-59-33.4-170.8-166.9-174.9-18000113.2P380 F385P380-E383 WeakPolarHBondContact O-CB 3.48Å; P380-E383 PolarHBondContact O-N 2.97Å; P380-E383 VanDerWaalsContact O-N 3.15Å; E383-F385 PolarHBondContact O-N 3.35Å
384I70.8Confident68.1Low19 Ų1957.3 Ų57.310%0.09729%0.289CS..G310 helixtrans-69.2-1918062.6172.1000113.6F382 N386 L548 D559 Q562F382-I384 PolarHBondContact O-N 3.47Å; F382-I384 VanDerWaalsContact O-N 3.16Å; I384-N386 VanDerWaalsContact C-N 3.29Å; I384-N386 PolarHBondContact O-N 3.49Å; I384-L548 VanDerWaalsContact O-CD1 3.25Å; I384-L548 WeakPolarHBondContact O-CD1 3.25Å; I384-L548 WeakPolarHBondContact O-CD2 3.21Å; I384-D559 HydrophobicContact CD1-CB 4.05Å; I384-D559 HydrophobicContact CG2-CB 4.31Å; I384-Q562 HydrophobicContact CD1-CB 4.1Å; I384-Q562 HydrophobicContact CD1-CG 4.13Å
385F74.8Confident70.9Confident1 Ų150 Ų500%0.00426%0.257CS..G310 helixtrans-92.725.4-176.8-63.5-68.4000113.1V323 F382 E383 G387 V388 L544 T563 M566V323-F385 HydrophobicContact CG1-CB 3.45Å; V323-F385 VanDerWaalsContact CG1-CB 3.45Å; V323-F385 HydrophobicContact CG1-CD1 3.98Å; V323-F385 HydrophobicContact CG1-CD2 3.84Å; V323-F385 HydrophobicContact CG1-CG 3.48Å; V323-F385 VanDerWaalsContact CG1-CG 3.48Å; F382-F385 PolarHBondContact O-N 3.12Å; E383-F385 PolarHBondContact O-N 3.35Å; F385-G387 PolarHBondContact O-N 2.95Å; F385-G387 VanDerWaalsContact O-N 3.15Å; F385-V388 HydrophobicContact CB-CB 4.38Å; F385-V388 WeakPolarHBondContact O-CB 3.36Å; F385-V388 PolarHBondContact O-N 2.68Å; F385-L544 HydrophobicContact CE1-CB 3.95Å; F385-L544 HydrophobicContact CE1-CD1 4.5Å; F385-L544 HydrophobicContact CZ-CD1 4.42Å; F385-T563 HydrophobicContact CZ-CG2 3.84Å; F385-T563 WeakPolarHBondContact CZ-OG1 3.43Å; F385-M566 HydrophobicContact CD2-CE 4.46Å; F385-M566 HydrophobicContact CE2-CE 3.61Å; F385-M566 HydrophobicContact CE2-CG 4.43Å; F385-M566 HydrophobicContact CZ-CE 3.85Å
386N68.7Low73.6Confident30 Ų3041.5 Ų41.516%0.1622%0.22CC..THydrogen-bonded Turntrans-52.5125.1-178.1-170.9-3.7000111.7Y325 E327 I384 V388 N552Y325-N386 HydrophobicContact CD1-CB 3.93Å; Y325-N386 WeakPolarHBondContact CD1-OD1 3.42Å; Y325-N386 HydrophobicContact CE1-CB 3.98Å; Y325-N386 WeakPolarHBondContact CE1-OD1 3.37Å; Y325-N386 HydrophobicContact CG-CB 4.34Å; E327-N386 PolarHBondContact OE1-ND2 2.88Å; I384-N386 VanDerWaalsContact C-N 3.29Å; I384-N386 PolarHBondContact O-N 3.49Å; N386-V388 PolarHBondContact O-N 2.71Å; N386-N552 PolarHBondContact O-ND2 3.23Å; N386-N552 VanDerWaalsContact O-ND2 3.12Å
387G71.4Confident76.5Confident25 Ų2536.8 Ų36.826%0.25820%0.199SC..THydrogen-bonded Turntrans78-13.8-17800000114.4F385 K389 K551F385-G387 PolarHBondContact O-N 2.95Å; F385-G387 VanDerWaalsContact O-N 3.15Å; G387-K389 PolarHBondContact O-N 3.25Å; G387-K551 WeakPolarHBondContact O-CD 3.46Å; G387-K551 WeakPolarHBondContact O-CE 3.35Å; G387-K551 PolarHBondContact O-NZ 3.24Å
388V82.1Confident79.3Confident7 Ų734.2 Ų34.24%0.04218%0.181CC..  trans-80.2119.6177.8-177.90000108.8F385 N386 R390 C547 L548 K551F385-V388 HydrophobicContact CB-CB 4.38Å; F385-V388 WeakPolarHBondContact O-CB 3.36Å; F385-V388 PolarHBondContact O-N 2.68Å; N386-V388 PolarHBondContact O-N 2.71Å; V388-R390 HydrophobicContact CG1-CB 4.46Å; V388-C547 HydrophobicContact CG1-CB 4.27Å; V388-L548 HydrophobicContact CG2-CB 4.22Å; V388-L548 HydrophobicContact CG2-CD1 3.85Å; V388-K551 HydrophobicContact CG2-CD 4.29Å
389K86.7Confident81.8Confident176 Ų17632.8 Ų32.877%0.76517%0.171SC*.EExtended strand (participates in β ladder)trans-113.7119168.3-174.8178179.2-179.30108.2V323 G387V323-K389 CarbonylContact O-C 3.57Å; V323-K389 VanDerWaalsContact O-CA 3.28Å; V323-K389 WeakPolarHBondContact O-CA 3.25Å; G387-K389 PolarHBondContact O-N 3.25Å
390R91.7Very high84Confident20 Ų2032.2 Ų32.28%0.07518%0.18CC..EExtended strand (participates in β ladder)trans-153.9144.8-179.9-152.7148.8176.376.33.5111.2V323 V388 Y392 N513 E516 D543 L544 C547V323-R390 PolarHBondContact N-O 2.7Å; V323-R390 PolarHBondContact O-N 2.77Å; V388-R390 HydrophobicContact CG1-CB 4.46Å; R390-Y392 HydrophobicContact CB-CE2 4.14Å; R390-Y392 WeakPolarHBondContact CD-OH 2.9Å; R390-Y392 HydrophobicContact CG-CE1 4.39Å; R390-Y392 HydrophobicContact CG-CE2 3.8Å; R390-Y392 WeakPolarHBondContact CG-OH 3.08Å; R390-Y392 PolarHBondContact NE-OH 2.99Å; R390-Y392 VanDerWaalsContact NE-OH 3.09Å; R390-N513 PolarHBondContact NH2-OD1 3.05Å; R390-E516 IonicContact CZ-OE1 2.84Å; R390-E516 IonicContact CZ-OE2 3.91Å; R390-E516 IonicContact NH1-OE1 3.73Å; R390-E516 PolarHBondContact NH1-OE1 3.12Å; R390-E516 IonicContact NH1-OE2 3.89Å; R390-E516 PolarHBondContact NH1-OE2 2.94Å; R390-E516 IonicContact NH2-OE2 2.87Å; R390-E516 PolarHBondContact NH2-OE2 2.78Å; R390-D543 IonicContact CZ-OD2 3.83Å; R390-D543 IonicContact NE-OD2 2.74Å; R390-D543 PolarHBondContact NE-OD2 3.47Å; R390-D543 IonicContact NH2-OD2 3.42Å; R390-D543 PolarHBondContact NH2-OD2 3.36Å; R390-D543 VanDerWaalsContact NH2-OD2 3.08Å; R390-L544 HydrophobicContact CB-CD2 4.15Å; R390-C547 PolarHBondContact NE-SG 2.89Å
391S96Very high86Confident17 Ų1731.5 Ų31.512%0.11918%0.176CC..EExtended strand (participates in β ladder)trans-132.8138.9-178.2-172.70000110.6L320 I321 P524 I525L320-S391 WeakPolarHBondContact CD1-OG 3.08Å; I321-S391 CarbonylContact O-C 3.56Å; I321-S391 WeakPolarHBondContact O-CA 3.49Å; S391-P524 WeakPolarHBondContact O-CA 3.4Å; S391-I525 PolarHBondContact O-N 3.22Å; S391-I525 VanDerWaalsContact O-N 3.08Å
392Y98.5Very high88Confident3 Ų330.9 Ų30.91%0.01217%0.174CC..EExtended strand (participates in β ladder)trans-134.7159.1177.6-48.9-95.3000110.1I321 R390 I525 V527 I540 D543 L544I321-Y392 HydrophobicContact CG2-CD2 4.35Å; I321-Y392 PolarHBondContact N-O 3.01Å; I321-Y392 PolarHBondContact O-N 3.05Å; R390-Y392 HydrophobicContact CB-CE2 4.14Å; R390-Y392 WeakPolarHBondContact CD-OH 2.9Å; R390-Y392 HydrophobicContact CG-CE1 4.39Å; R390-Y392 HydrophobicContact CG-CE2 3.8Å; R390-Y392 WeakPolarHBondContact CG-OH 3.08Å; R390-Y392 PolarHBondContact NE-OH 2.99Å; R390-Y392 VanDerWaalsContact NE-OH 3.09Å; Y392-I525 CarbonylContact C-O 3.52Å; Y392-I525 WeakPolarHBondContact CA-O 3.37Å; Y392-I525 WeakPolarHBondContact CB-O 3.26Å; Y392-I525 HydrophobicContact CD1-CB 3.99Å; Y392-I525 HydrophobicContact CE1-CD1 4.42Å; Y392-V527 HydrophobicContact CD1-CG2 4.14Å; Y392-I540 HydrophobicContact CD1-CG1 4.13Å; Y392-I540 HydrophobicContact CD1-CG2 4.46Å; Y392-I540 HydrophobicContact CD2-CG2 3.84Å; Y392-I540 HydrophobicContact CE1-CG2 4.47Å; Y392-I540 HydrophobicContact CE2-CG2 3.83Å; Y392-I540 HydrophobicContact CG-CD1 4.23Å; Y392-I540 HydrophobicContact CG-CG1 4.25Å; Y392-I540 HydrophobicContact CG-CG2 4.15Å; Y392-D543 PolarHBondContact OH-OD2 2.74Å; Y392-L544 HydrophobicContact CE2-CD1 4.36Å; Y392-L544 HydrophobicContact CE2-CD2 3.74Å; Y392-L544 HydrophobicContact CE2-CG 3.89Å
393I98.8Very high89.8Confident0 Ų030.6 Ų30.60%018%0.175CC..EExtended strand (participates in β ladder)trans-117.5116.8164.3-65.8170000107.7I301 A318 N319 L320 M409 E413 P524 I525 I526 V527I301-I393 HydrophobicContact CD1-CD1 4.11Å; I301-I393 HydrophobicContact CD1-CG1 4.05Å; I301-I393 HydrophobicContact CG1-CD1 4.46Å; I301-I393 HydrophobicContact CG1-CG1 4.42Å; I301-I393 HydrophobicContact CG1-CG2 4.04Å; A318-I393 HydrophobicContact CB-CG2 3.93Å; N319-I393 WeakPolarHBondContact O-CA 3.35Å; L320-I393 HydrophobicContact CD1-CG1 4.26Å; I393-M409 HydrophobicContact CD1-CG 4.45Å; I393-M409 HydrophobicContact CG2-CE 3.95Å; I393-M409 HydrophobicContact CG2-SD 3.69Å; I393-E413 HydrophobicContact CD1-CB 3.78Å; I393-E413 HydrophobicContact CD1-CG 3.7Å; I393-P524 HydrophobicContact CD1-CB 3.9Å; I393-P524 HydrophobicContact CD1-CG 4.41Å; I393-P524 HydrophobicContact CG1-CB 3.74Å; I393-I525 PolarHBondContact N-O 2.62Å; I393-I526 HydrophobicContact CB-CG1 3.94Å; I393-I526 HydrophobicContact CD1-CG1 4.14Å; I393-I526 HydrophobicContact CG2-CG1 4.39Å; I393-I526 CarbonylContact O-C 3.51Å; I393-I526 WeakPolarHBondContact O-CA 3.31Å; I393-V527 PolarHBondContact O-N 2.86Å
394S98.8Very high91.5Very high0 Ų027.5 Ų27.50%016%0.162CC..EExtended strand (participates in β ladder)trans-95.5117.8174.9-173.10000109.8A318 N319 V527 G532 T536 R571A318-S394 CarbonylContact C-O 3.56Å; A318-S394 VanDerWaalsContact CA-O 3.3Å; A318-S394 WeakPolarHBondContact CA-O 3.3Å; N319-S394 PolarHBondContact N-O 3.41Å; N319-S394 PolarHBondContact O-N 2.9Å; S394-V527 WeakPolarHBondContact CA-O 3.47Å; S394-G532 PolarHBondContact OG-O 2.98Å; S394-T536 WeakPolarHBondContact OG-CG2 3.32Å; S394-R571 VanDerWaalsContact OG-CD 3.24Å; S394-R571 WeakPolarHBondContact OG-CD 3.28Å
395T98.8Very high92.8Very high2 Ų227.2 Ų27.21%0.01216%0.161CC..EExtended strand (participates in β ladder)trans-135.2161-174.9-1720000112.5N317 F406 M409 I526 V527 H528 G532N317-T395 PolarHBondContact O-OG1 3.4Å; T395-F406 HydrophobicContact CG2-CD2 4.46Å; T395-F406 HydrophobicContact CG2-CE2 4.05Å; T395-M409 HydrophobicContact CG2-CE 4.15Å; T395-I526 HydrophobicContact CG2-CG2 3.93Å; T395-V527 PolarHBondContact N-O 2.83Å; T395-H528 HydrophobicContact CG2-CB 3.63Å; T395-H528 WeakPolarHBondContact O-CA 3.37Å; T395-H528 WeakPolarHBondContact O-CB 3.28Å; T395-G532 WeakPolarHBondContact O-CA 3.49Å
396Q98.6Very high93.9Very high7 Ų727.2 Ų27.23%0.03316%0.161CC..PPolyproline II helixtrans-70.7161.9172.269.1178.635.200111.5K287 N317 C398K287-Q396 PolarHBondContact O-NE2 3.23Å; N317-Q396 HydrophobicContact CB-CG 4.13Å; N317-Q396 PolarHBondContact ND2-OE1 2.9Å; N317-Q396 PolarHBondContact O-N 3.46Å; Q396-C398 PolarHBondContact O-N 3.47Å
397G98.6Very high95.3Very high0 Ų025.8 Ų25.80%015%0.153CC..PPolyproline II helixtrans-65.7133.716700000110.6R289 L399 C529 S530R289-G397 VanDerWaalsContact CZ-O 3.32Å; R289-G397 PolarHBondContact NE-O 3.39Å; R289-G397 PolarHBondContact NH2-O 3.32Å; G397-L399 PolarHBondContact O-N 2.62Å; G397-C529 WeakPolarHBondContact CA-O 3.44Å; G397-C529 PolarHBondContact N-O 3.49Å; G397-C529 VanDerWaalsContact N-O 3.11Å; G397-S530 PolarHBondContact N-O 3.23Å
398C98.7Very high96.6Very high2 Ų224.6 Ų24.61%0.01414%0.141CC..PPolyproline II helixtrans-51.7136-176.6-65.30000112.9R289 Q396 V403 F406 C432 V433 Y435R289-C398 PolarHBondContact NH2-O 2.81Å; Q396-C398 PolarHBondContact O-N 3.47Å; C398-V403 HydrophobicContact CB-CG2 4.44Å; C398-F406 VanDerWaalsContact SG-CD2 3.53Å; C398-F406 WeakPolarHBondContact SG-CG 3.47Å; C398-C432 PolarHBondContact N-SG 3.34Å; C398-V433 HydrophobicContact CB-CG2 3.97Å; C398-V433 WeakPolarHBondContact O-CG2 3.46Å; C398-V433 PolarHBondContact O-N 3.28Å; C398-Y435 HydrophobicContact CB-CD1 3.95Å; C398-Y435 HydrophobicContact CB-CG 4.38Å
399L98.4Very high97.4Very high33 Ų3324.3 Ų24.317%0.17314%0.139CC..PPolyproline II helixtrans-91.9162.4162.7-59.6170.8000108.5R289 G397 C401 T402 V403R289-L399 HydrophobicContact CB-CD1 4.48Å; R289-L399 HydrophobicContact CB-CD2 4.15Å; R289-L399 HydrophobicContact CB-CG 4.45Å; R289-L399 HydrophobicContact CG-CD2 4.24Å; G397-L399 PolarHBondContact O-N 2.62Å; L399-C401 PolarHBondContact O-N 2.87Å; L399-T402 HydrophobicContact CB-CG2 4.18Å; L399-T402 HydrophobicContact CD1-CG2 4.33Å; L399-T402 PolarHBondContact N-OG1 2.84Å; L399-T402 PolarHBondContact O-N 3.5Å; L399-T402 PolarHBondContact O-OG1 2.81Å; L399-V403 WeakPolarHBondContact O-CG2 3.22Å; L399-V403 PolarHBondContact O-N 3.39Å
400A98.1Very high97.9Very high84 Ų8416 Ų1669%0.69410%0.103SC*.G310 helixtrans-54.8-38.8175.800000112.2T402A400-T402 VanDerWaalsContact C-N 3.33Å; A400-T402 PolarHBondContact O-N 2.93Å
401C97Very high98.2Very high76 Ų7616.2 Ų16.251%0.51410%0.104SC..G310 helixtrans-77.8-7.3178.5580000115.2L399L399-C401 PolarHBondContact O-N 2.87Å
402T98.2Very high98.3Very high7 Ų716.4 Ų16.44%0.04310%0.103CC..G310 helixtrans-116.98.4-177.170.70000113.1K287 L399 A400 D404 F406K287-T402 HydrophobicContact CB-CG2 3.97Å; K287-T402 HydrophobicContact CG-CG2 4.36Å; L399-T402 HydrophobicContact CB-CG2 4.18Å; L399-T402 HydrophobicContact CD1-CG2 4.33Å; L399-T402 PolarHBondContact N-OG1 2.84Å; L399-T402 PolarHBondContact O-N 3.5Å; L399-T402 PolarHBondContact O-OG1 2.81Å; A400-T402 VanDerWaalsContact C-N 3.33Å; A400-T402 PolarHBondContact O-N 2.93Å; T402-D404 VanDerWaalsContact C-N 3.34Å; T402-F406 WeakPolarHBondContact O-CB 3.25Å; T402-F406 PolarHBondContact O-N 3.36Å
403V98.5Very high98.2Very high30 Ų3018 Ų1818%0.18211%0.11CC..Hα-helixtrans-63.7-42.1178.5173.40000110.8C398 L399 F406 W407 V433C398-V403 HydrophobicContact CB-CG2 4.44Å; L399-V403 WeakPolarHBondContact O-CG2 3.22Å; L399-V403 PolarHBondContact O-N 3.39Å; V403-F406 PolarHBondContact O-N 3.46Å; V403-W407 VanDerWaalsContact O-CD1 3.29Å; V403-W407 PolarHBondContact O-N 3.22Å; V403-W407 VanDerWaalsContact O-N 3.15Å; V403-V433 HydrophobicContact CG2-CG2 3.78Å
404D97.7Very high98.1Very high39 Ų3921.6 Ų21.621%0.20913%0.127CC..Hα-helixtrans-65.3-49178.1-67.9-47.5000111.3T402 F406 W407 E408 T445 G446 K449T402-D404 VanDerWaalsContact C-N 3.34Å; D404-F406 VanDerWaalsContact C-N 3.26Å; D404-F406 PolarHBondContact O-N 3.22Å; D404-W407 PolarHBondContact O-N 3.06Å; D404-E408 PolarHBondContact O-N 2.93Å; D404-T445 VanDerWaalsContact OD1-CA 3.28Å; D404-T445 WeakPolarHBondContact OD1-CA 3.26Å; D404-T445 PolarHBondContact OD1-OG1 3.4Å; D404-G446 WeakPolarHBondContact O-CA 3.25Å; D404-G446 PolarHBondContact OD1-N 3.48Å; D404-G446 VanDerWaalsContact OD1-N 3.1Å; D404-K449 IonicContact OD1-NZ 3.98Å; D404-K449 PolarHBondContact OD1-NZ 2.95Å; D404-K449 WeakPolarHBondContact OD2-CE 3.31Å; D404-K449 IonicContact OD2-NZ 2.62Å; D404-K449 PolarHBondContact OD2-NZ 3.09Å
405D98.2Very high98.1Very high12 Ų1221.6 Ų21.66%0.06413%0.127CC..Hα-helixtrans-54.2-42.5174.9-68-7.6000111.7K287 L303 I316 E408 M409 F447K287-D405 WeakPolarHBondContact CE-OD2 3.21Å; K287-D405 IonicContact NZ-OD1 3.91Å; K287-D405 IonicContact NZ-OD2 3.64Å; K287-D405 PolarHBondContact NZ-OD2 2.92Å; L303-D405 HydrophobicContact CD1-CB 3.73Å; I316-D405 HydrophobicContact CD1-CB 4.17Å; D405-E408 PolarHBondContact O-N 3.35Å; D405-M409 PolarHBondContact O-N 2.86Å; D405-F447 WeakPolarHBondContact OD1-CE1 3.45Å
406F98.7Very high98.1Very high1 Ų124.6 Ų24.60%0.00414%0.138CC..Hα-helixtrans-64.1-45.7179.5177.6-93000112.4I316 T395 C398 T402 V403 D404 E408 M409 V410 I418 Y435 I526I316-F406 HydrophobicContact CD1-CB 4.48Å; T395-F406 HydrophobicContact CG2-CD2 4.46Å; T395-F406 HydrophobicContact CG2-CE2 4.05Å; C398-F406 VanDerWaalsContact SG-CD2 3.53Å; C398-F406 WeakPolarHBondContact SG-CG 3.47Å; T402-F406 WeakPolarHBondContact O-CB 3.25Å; T402-F406 PolarHBondContact O-N 3.36Å; V403-F406 PolarHBondContact O-N 3.46Å; D404-F406 VanDerWaalsContact C-N 3.26Å; D404-F406 PolarHBondContact O-N 3.22Å; F406-E408 VanDerWaalsContact C-N 3.34Å; F406-M409 HydrophobicContact CD2-CE 3.91Å; F406-M409 HydrophobicContact CE2-CE 4.04Å; F406-M409 WeakPolarHBondContact O-CB 3.09Å; F406-M409 PolarHBondContact O-N 3.36Å; F406-V410 HydrophobicContact CD1-CG2 4.1Å; F406-V410 HydrophobicContact CE1-CG2 3.71Å; F406-V410 HydrophobicContact CZ-CG2 4.06Å; F406-V410 VanDerWaalsContact O-CG2 3.28Å; F406-V410 WeakPolarHBondContact O-CG2 3.3Å; F406-V410 PolarHBondContact O-N 3.37Å; F406-I418 HydrophobicContact CE1-CD1 4.03Å; F406-I418 HydrophobicContact CZ-CD1 4.05Å; F406-I418 HydrophobicContact CZ-CG2 4.14Å; F406-Y435 AromaticContact CD1-CD2 3.85Å; F406-Y435 HydrophobicContact CD1-CD2 3.85Å; F406-Y435 HydrophobicContact CD1-CE2 4.17Å; F406-Y435 HydrophobicContact CD1-CG 4.36Å; F406-Y435 AromaticContact CE1-CD2 3.5Å; F406-Y435 HydrophobicContact CE1-CD2 3.5Å; F406-Y435 AromaticContact CE1-CE2 3.35Å; F406-Y435 HydrophobicContact CE1-CE2 3.35Å; F406-Y435 HydrophobicContact CE1-CG 4.31Å; F406-Y435 HydrophobicContact CZ-CD2 4.3Å; F406-Y435 AromaticContact CZ-CE2 3.79Å; F406-Y435 HydrophobicContact CZ-CE2 3.79Å; F406-I526 HydrophobicContact CE2-CG2 4.06Å; F406-I526 HydrophobicContact CZ-CG2 4.27Å
407W98.3Very high98.1Very high0 Ų024.5 Ų24.50%014%0.138CC..Hα-helixtrans-73.3-28.5178.9-77.1109.9000113.1V403 D404 V410 W411 I418 Y435 T445 I451 L453 L469 L471V403-W407 VanDerWaalsContact O-CD1 3.29Å; V403-W407 PolarHBondContact O-N 3.22Å; V403-W407 VanDerWaalsContact O-N 3.15Å; D404-W407 PolarHBondContact O-N 3.06Å; W407-V410 HydrophobicContact CE3-CB 3.92Å; W407-V410 HydrophobicContact CE3-CG1 3.99Å; W407-V410 HydrophobicContact CE3-CG2 3.96Å; W407-V410 HydrophobicContact CZ3-CB 4.27Å; W407-V410 HydrophobicContact CZ3-CG1 3.9Å; W407-V410 HydrophobicContact CZ3-CG2 4.17Å; W407-V410 PolarHBondContact O-N 3.31Å; W407-W411 WeakPolarHBondContact O-CB 3.22Å; W407-W411 PolarHBondContact O-N 3.46Å; W407-I418 HydrophobicContact CH2-CD1 4.01Å; W407-I418 HydrophobicContact CZ3-CD1 4.11Å; W407-Y435 AromaticContact CE2-CD2 3.97Å; W407-Y435 AromaticContact CZ2-CD2 3.69Å; W407-Y435 HydrophobicContact CZ2-CD2 3.69Å; W407-Y435 HydrophobicContact CZ2-CE2 4.09Å; W407-Y435 AromaticContact NE1-CD2 3.95Å; W407-Y435 PolarHBondContact NE1-O 3.04Å; W407-T445 HydrophobicContact CB-CG2 3.53Å; W407-T445 HydrophobicContact CD2-CG2 4.32Å; W407-T445 HydrophobicContact CG-CG2 3.51Å; W407-I451 HydrophobicContact CB-CD1 4.44Å; W407-L453 HydrophobicContact CD2-CD2 4.09Å; W407-L453 HydrophobicContact CH2-CD1 3.85Å; W407-L453 HydrophobicContact CH2-CD2 4.01Å; W407-L453 HydrophobicContact CZ2-CD1 4.03Å; W407-L453 HydrophobicContact CZ2-CD2 3.3Å; W407-L453 HydrophobicContact CZ2-CG 4.32Å; W407-L453 HydrophobicContact CZ3-CD1 4.1Å; W407-L469 HydrophobicContact CH2-CD1 3.56Å; W407-L469 HydrophobicContact CZ2-CD1 4.11Å; W407-L471 HydrophobicContact CE3-CD1 4.45Å; W407-L471 HydrophobicContact CE3-CD2 3.71Å; W407-L471 HydrophobicContact CE3-CG 4.16Å; W407-L471 HydrophobicContact CH2-CD1 4.39Å; W407-L471 HydrophobicContact CZ3-CD1 3.78Å; W407-L471 HydrophobicContact CZ3-CD2 3.72Å; W407-L471 HydrophobicContact CZ3-CG 3.99Å
408E97.7Very high98.1Very high1 Ų124.5 Ų24.51%0.00514%0.138CC..Hα-helixtrans-63.9-44.2169.3-163.870.6-140.900110.9D404 D405 F406 V410 W411 Q412 F447 K473D404-E408 PolarHBondContact O-N 2.93Å; D405-E408 PolarHBondContact O-N 3.35Å; F406-E408 VanDerWaalsContact C-N 3.34Å; E408-V410 PolarHBondContact O-N 2.94Å; E408-W411 PolarHBondContact O-N 3.07Å; E408-Q412 WeakPolarHBondContact O-CG 3.27Å; E408-Q412 PolarHBondContact O-N 2.92Å; E408-F447 HydrophobicContact CB-CD2 4.33Å; E408-F447 HydrophobicContact CB-CE2 4.24Å; E408-F447 HydrophobicContact CB-CZ 4.39Å; E408-F447 HydrophobicContact CG-CD2 3.53Å; E408-F447 HydrophobicContact CG-CE2 3.51Å; E408-F447 HydrophobicContact CG-CG 4.2Å; E408-F447 HydrophobicContact CG-CZ 4.14Å; E408-F447 PolarHBondContact OE2-N 3.46Å; E408-F447 VanDerWaalsContact OE2-N 3.07Å; E408-K473 IonicContact OE1-NZ 2.95Å; E408-K473 PolarHBondContact OE1-NZ 3.45Å; E408-K473 IonicContact OE2-NZ 2.88Å; E408-K473 PolarHBondContact OE2-NZ 2.94Å
409M98.5Very high98.1Very high0 Ų024.6 Ų24.60%014%0.139CC..Hα-helixtrans-55.6-50.4172.9-177.3178.971.400111.8I301 L303 I316 A318 I393 T395 D405 F406 W411 Q412 E413 I526I301-M409 HydrophobicContact CB-SD 4.31Å; I301-M409 HydrophobicContact CG1-SD 4.17Å; I301-M409 HydrophobicContact CG2-CG 3.95Å; I301-M409 HydrophobicContact CG2-SD 4.23Å; L303-M409 HydrophobicContact CD2-CB 3.82Å; I316-M409 HydrophobicContact CD1-CB 4.17Å; I316-M409 HydrophobicContact CD1-CE 4.23Å; I316-M409 HydrophobicContact CD1-SD 3.92Å; I316-M409 HydrophobicContact CG2-SD 4.22Å; A318-M409 HydrophobicContact CB-SD 3.66Å; I393-M409 HydrophobicContact CD1-CG 4.45Å; I393-M409 HydrophobicContact CG2-CE 3.95Å; I393-M409 HydrophobicContact CG2-SD 3.69Å; T395-M409 HydrophobicContact CG2-CE 4.15Å; D405-M409 PolarHBondContact O-N 2.86Å; F406-M409 HydrophobicContact CD2-CE 3.91Å; F406-M409 HydrophobicContact CE2-CE 4.04Å; F406-M409 WeakPolarHBondContact O-CB 3.09Å; F406-M409 PolarHBondContact O-N 3.36Å; M409-W411 VanDerWaalsContact C-N 3.25Å; M409-W411 PolarHBondContact O-N 2.79Å; M409-Q412 WeakPolarHBondContact O-CG 3.44Å; M409-Q412 PolarHBondContact O-N 3.26Å; M409-E413 HydrophobicContact CG-CG 4.31Å; M409-E413 WeakPolarHBondContact O-CB 3.42Å; M409-E413 WeakPolarHBondContact O-CG 3.4Å; M409-E413 PolarHBondContact O-N 3.05Å; M409-I526 HydrophobicContact CE-CD1 4.08Å; M409-I526 HydrophobicContact CE-CG1 4.38Å; M409-I526 HydrophobicContact CE-CG2 4.39Å
410V98.6Very high98.1Very high2 Ų223 Ų231%0.01213%0.13CC..Hα-helixtrans-57.3-41.8178.1175.80000110.9F406 W407 E408 E414 S415 I418 L471 V485 I526F406-V410 HydrophobicContact CD1-CG2 4.1Å; F406-V410 HydrophobicContact CE1-CG2 3.71Å; F406-V410 HydrophobicContact CZ-CG2 4.06Å; F406-V410 VanDerWaalsContact O-CG2 3.28Å; F406-V410 WeakPolarHBondContact O-CG2 3.3Å; F406-V410 PolarHBondContact O-N 3.37Å; W407-V410 HydrophobicContact CE3-CB 3.92Å; W407-V410 HydrophobicContact CE3-CG1 3.99Å; W407-V410 HydrophobicContact CE3-CG2 3.96Å; W407-V410 HydrophobicContact CZ3-CB 4.27Å; W407-V410 HydrophobicContact CZ3-CG1 3.9Å; W407-V410 HydrophobicContact CZ3-CG2 4.17Å; W407-V410 PolarHBondContact O-N 3.31Å; E408-V410 PolarHBondContact O-N 2.94Å; V410-E414 PolarHBondContact O-N 3.41Å; V410-S415 PolarHBondContact O-N 2.68Å; V410-I418 HydrophobicContact CG1-CD1 4.45Å; V410-I418 HydrophobicContact CG2-CD1 3.96Å; V410-L471 HydrophobicContact CG1-CD2 3.84Å; V410-V485 HydrophobicContact CG1-CG2 4.04Å; V410-I526 HydrophobicContact CB-CD1 4.21Å; V410-I526 HydrophobicContact CG2-CD1 3.46Å; V410-I526 VanDerWaalsContact CG2-CD1 3.46Å
411W97.7Very high98.1Very high25 Ų2519 Ų1910%0.09510%0.097CC..Hα-helixtrans-68.6-51.9179.5-175.4-87.4000112.3W407 E408 M409 E413 E414 I451 L471 K473 E481 R483W407-W411 WeakPolarHBondContact O-CB 3.22Å; W407-W411 PolarHBondContact O-N 3.46Å; E408-W411 PolarHBondContact O-N 3.07Å; M409-W411 VanDerWaalsContact C-N 3.25Å; M409-W411 PolarHBondContact O-N 2.79Å; W411-E413 PolarHBondContact O-N 3.32Å; W411-E414 PolarHBondContact O-N 3.08Å; W411-I451 HydrophobicContact CB-CD1 3.77Å; W411-I451 HydrophobicContact CG-CD1 4.15Å; W411-L471 HydrophobicContact CE3-CB 4.25Å; W411-L471 HydrophobicContact CE3-CD2 4.39Å; W411-L471 HydrophobicContact CZ3-CB 4.12Å; W411-K473 HydrophobicContact CD2-CB 4.04Å; W411-K473 HydrophobicContact CD2-CD 3.88Å; W411-K473 HydrophobicContact CE3-CB 4.04Å; W411-K473 HydrophobicContact CG-CD 4.07Å; W411-K473 HydrophobicContact CH2-CB 3.36Å; W411-K473 HydrophobicContact CZ2-CB 3.35Å; W411-K473 HydrophobicContact CZ2-CD 4.05Å; W411-K473 HydrophobicContact CZ2-CG 4.26Å; W411-K473 HydrophobicContact CZ3-CB 3.71Å; W411-E481 HydrophobicContact CH2-CB 3.9Å; W411-E481 HydrophobicContact CH2-CG 3.98Å; W411-E481 WeakPolarHBondContact CH2-O 3.09Å; W411-E481 HydrophobicContact CZ2-CB 4.1Å; W411-E481 HydrophobicContact CZ2-CG 4.2Å; W411-R483 HydrophobicContact CH2-CG 4.45Å; W411-R483 HydrophobicContact CZ3-CG 4.34Å; W411-R483 PolarHBondContact O-NH1 3.17Å
412Q97.3Very high98Very high20 Ų2015.5 Ų15.59%0.0937%0.073CC..Hα-helixtrans-70.1-32.2-173.873.5171.645.800113.3V302 R304 E408 M409V302-Q412 PolarHBondContact O-NE2 2.72Å; R304-Q412 PolarHBondContact NH2-O 3.38Å; E408-Q412 WeakPolarHBondContact O-CG 3.27Å; E408-Q412 PolarHBondContact O-N 2.92Å; M409-Q412 WeakPolarHBondContact O-CG 3.44Å; M409-Q412 PolarHBondContact O-N 3.26Å
413E97.6Very high97.9Very high37 Ų3719.3 Ų19.317%0.1739%0.09CC..THydrogen-bonded Turntrans-87.6-1.1178.5-59.2-50.9131.100111.7I301 R304 I393 M409 W411 S415I301-E413 HydrophobicContact CG2-CG 4.4Å; R304-E413 IonicContact CZ-OE1 3.62Å; R304-E413 IonicContact NH2-OE1 2.71Å; R304-E413 PolarHBondContact NH2-OE1 3.05Å; R304-E413 IonicContact NH2-OE2 3.47Å; I393-E413 HydrophobicContact CD1-CB 3.78Å; I393-E413 HydrophobicContact CD1-CG 3.7Å; M409-E413 HydrophobicContact CG-CG 4.31Å; M409-E413 WeakPolarHBondContact O-CB 3.42Å; M409-E413 WeakPolarHBondContact O-CG 3.4Å; M409-E413 PolarHBondContact O-N 3.05Å; W411-E413 PolarHBondContact O-N 3.32Å; E413-S415 PolarHBondContact O-N 2.96Å
414E97Very high97.9Very high75 Ų7521.2 Ų21.235%0.3510%0.096SC..THydrogen-bonded Turntrans55.923.5179.1-52.5174.9-102.600113.2V410 W411 R416 K523V410-E414 PolarHBondContact O-N 3.41Å; W411-E414 PolarHBondContact O-N 3.08Å; E414-R416 WeakPolarHBondContact O-CD 3.35Å; E414-R416 WeakPolarHBondContact O-CG 3.35Å; E414-R416 PolarHBondContact O-N 3.27Å; E414-K523 HydrophobicContact CB-CD 3.96Å; E414-K523 HydrophobicContact CB-CG 4.13Å; E414-K523 IonicContact OE1-NZ 3.96Å; E414-K523 PolarHBondContact OE1-NZ 3.49Å; E414-K523 IonicContact OE2-NZ 3.16Å; E414-K523 PolarHBondContact OE2-NZ 2.77Å
415S98.2Very high97.8Very high1 Ų124.6 Ų24.61%0.00711%0.113CC..  trans-60.1123.9-178.8-70.20000110.7V410 E413 P524 I526V410-S415 PolarHBondContact O-N 2.68Å; E413-S415 PolarHBondContact O-N 2.96Å; S415-P524 VanDerWaalsContact CB-O 3.28Å; S415-P524 WeakPolarHBondContact CB-O 3.14Å; S415-P524 PolarHBondContact OG-O 2.74Å; S415-I526 VanDerWaalsContact CB-CD1 3.46Å
416R97.9Very high97.6Very high64 Ų6424.6 Ų24.624%0.24211%0.113CC..  trans-97.7-16.2-178.7-56.2-54.3-62.4-121.2-12.8113.4E414 F484 V485 Y486 L519E414-R416 WeakPolarHBondContact O-CD 3.35Å; E414-R416 WeakPolarHBondContact O-CG 3.35Å; E414-R416 PolarHBondContact O-N 3.27Å; R416-F484 PolarHBondContact NE-O 3.25Å; R416-F484 PolarHBondContact NH2-O 3.33Å; R416-V485 CarbonylContact O-C 3.55Å; R416-V485 WeakPolarHBondContact O-CA 3.02Å; R416-Y486 PolarHBondContact O-N 3.1Å; R416-L519 HydrophobicContact CB-CD1 3.59Å; R416-L519 HydrophobicContact CG-CD1 4.16Å
417I98.7Very high97.2Very high5 Ų531.8 Ų31.83%0.02614%0.14CC..EExtended strand (participates in β ladder)trans-129.3130.4-174.6-55.1177000109V419 Y486 Y488 I512 L515 E516 L519 I525 I526I417-V419 HydrophobicContact CG2-CG2 4.35Å; I417-Y486 WeakPolarHBondContact CA-O 3.46Å; I417-Y488 HydrophobicContact CG2-CD2 4.13Å; I417-Y488 HydrophobicContact CG2-CE2 4.49Å; I417-I512 HydrophobicContact CD1-CG2 4.31Å; I417-I512 HydrophobicContact CG2-CG2 4.04Å; I417-L515 HydrophobicContact CD1-CD2 4.02Å; I417-L515 HydrophobicContact CD1-CG 4.21Å; I417-L515 HydrophobicContact CG1-CD2 4.09Å; I417-E516 HydrophobicContact CD1-CB 3.76Å; I417-E516 HydrophobicContact CD1-CG 4.27Å; I417-L519 HydrophobicContact CD1-CD1 4.13Å; I417-L519 HydrophobicContact CG1-CD1 4.19Å; I417-I525 HydrophobicContact CB-CG1 4.43Å; I417-I525 HydrophobicContact CB-CG2 4.24Å; I417-I525 HydrophobicContact CG2-CG2 4.02Å; I417-I526 PolarHBondContact O-N 2.99Å
418I98.9Very high96.9Very high0 Ų035.2 Ų35.20%018%0.176CC..EExtended strand (participates in β ladder)trans-122.1127174.2-57.2169.6000108.4F406 W407 V410 Y435 V485 Y486 H487 Y488 I526F406-I418 HydrophobicContact CE1-CD1 4.03Å; F406-I418 HydrophobicContact CZ-CD1 4.05Å; F406-I418 HydrophobicContact CZ-CG2 4.14Å; W407-I418 HydrophobicContact CH2-CD1 4.01Å; W407-I418 HydrophobicContact CZ3-CD1 4.11Å; V410-I418 HydrophobicContact CG1-CD1 4.45Å; V410-I418 HydrophobicContact CG2-CD1 3.96Å; I418-Y435 WeakPolarHBondContact CG2-OH 3.47Å; I418-V485 HydrophobicContact CD1-CG1 3.58Å; I418-V485 HydrophobicContact CG1-CG1 3.87Å; I418-Y486 PolarHBondContact N-O 3.37Å; I418-H487 CarbonylContact O-C 3.56Å; I418-Y488 PolarHBondContact O-N 2.86Å; I418-I526 CarbonylContact C-O 3.43Å; I418-I526 WeakPolarHBondContact CA-O 3.45Å; I418-I526 HydrophobicContact CG1-CB 4.25Å; I418-I526 HydrophobicContact CG1-CD1 4.26Å; I418-I526 HydrophobicContact CG2-CB 4.44Å; I418-I526 HydrophobicContact CG2-CG2 4.21Å
419V98.8Very high96.8Very high4 Ų442.1 Ų42.12%0.02421%0.206CC..EExtended strand (participates in β ladder)trans-110.9113.2177.1178.60000109.3I417 Y488 F508 I512 I525 I526 V527 H528I417-V419 HydrophobicContact CG2-CG2 4.35Å; V419-Y488 CarbonylContact C-O 3.58Å; V419-Y488 WeakPolarHBondContact CA-O 3.2Å; V419-F508 HydrophobicContact CG1-CE1 3.68Å; V419-F508 HydrophobicContact CG1-CZ 3.91Å; V419-I512 HydrophobicContact CG2-CD1 3.6Å; V419-I525 HydrophobicContact CG2-CG2 3.93Å; V419-I526 PolarHBondContact N-O 3.28Å; V419-V527 HydrophobicContact CB-CB 4.36Å; V419-V527 HydrophobicContact CB-CG1 4.05Å; V419-V527 HydrophobicContact CB-CG2 4.16Å; V419-V527 HydrophobicContact CG1-CG1 4Å; V419-V527 HydrophobicContact CG2-CG2 4.46Å; V419-V527 CarbonylContact O-C 3.52Å; V419-V527 WeakPolarHBondContact O-CA 3.18Å; V419-H528 PolarHBondContact O-N 3.43Å
420M98.7Very high96.7Very high0 Ų045.3 Ų45.30%023%0.228CC..EExtended strand (participates in β ladder)trans-104.9112.9176.8177.8169179.900110.1T422 E424 C432 Y435 W436 Y488 H489 F490 H528M420-T422 HydrophobicContact CE-CG2 4.14Å; M420-T422 WeakPolarHBondContact CE-O 3.44Å; M420-E424 HydrophobicContact CE-CG 4.36Å; M420-C432 HydrophobicContact CE-CB 3.74Å; M420-Y435 HydrophobicContact SD-CE1 4.18Å; M420-W436 HydrophobicContact CE-CH2 3.92Å; M420-W436 HydrophobicContact CE-CZ3 4.16Å; M420-W436 HydrophobicContact SD-CH2 3.62Å; M420-W436 HydrophobicContact SD-CZ3 3.54Å; M420-W436 VanDerWaalsContact SD-CZ3 3.54Å; M420-Y488 PolarHBondContact N-O 2.76Å; M420-H489 HydrophobicContact CB-CB 4.42Å; M420-H489 CarbonylContact O-C 3.58Å; M420-H489 WeakPolarHBondContact O-CA 3.34Å; M420-H489 PolarHBondContact O-CD2 3.46Å; M420-F490 PolarHBondContact O-N 2.88Å; M420-H528 WeakPolarHBondContact CB-NE2 3.39Å; M420-H528 VanDerWaalsContact CG-CE1 3.45Å; M420-H528 WeakPolarHBondContact CG-CE1 3.37Å
421A97.4Very high96.6Very high0 Ų047.4 Ų47.40%024%0.237CC..  trans-104.329.8-175.800000113.7H528 C529 R535 F539A421-H528 PolarHBondContact N-O 2.72Å; A421-C529 HydrophobicContact CB-CB 4.17Å; A421-R535 HydrophobicContact CB-CB 4.07Å; A421-R535 WeakPolarHBondContact O-CD 3.31Å; A421-R535 PolarHBondContact O-NH1 2.81Å; A421-F539 HydrophobicContact CB-CD2 3.86Å; A421-F539 HydrophobicContact CB-CE2 3.6Å
422T96.4Very high96.6Very high2 Ų246.2 Ų46.21%0.01223%0.233CC..SBendtrans-150150.7178.7-165.30000110.3M420 E426 K431 C432 H489 C529 R535M420-T422 HydrophobicContact CE-CG2 4.14Å; M420-T422 WeakPolarHBondContact CE-O 3.44Å; T422-E426 PolarHBondContact OG1-OE1 2.91Å; T422-K431 HydrophobicContact CG2-CB 4.18Å; T422-K431 WeakPolarHBondContact OG1-CB 3.38Å; T422-C432 HydrophobicContact CG2-CB 4.15Å; T422-H489 PolarHBondContact O-NE2 3.3Å; T422-C529 VanDerWaalsContact CG2-C 3.44Å; T422-R535 PolarHBondContact OG1-NH1 3.35Å
423K96.3Very high96.7Very high88 Ų8847 Ų4738%0.38324%0.239SC..  trans-75.1161.7166.8-63.4173.3-174.7171.20109.2I425 E426 K431 L491K423-I425 VanDerWaalsContact C-N 3.26Å; K423-I425 PolarHBondContact O-N 3.04Å; K423-E426 HydrophobicContact CB-CG 4.01Å; K423-E426 PolarHBondContact N-OE1 2.97Å; K423-E426 VanDerWaalsContact N-OE1 3.08Å; K423-K431 WeakPolarHBondContact O-CB 3.24Å; K423-L491 WeakPolarHBondContact CE-O 3.25Å; K423-L491 HydrophobicContact CG-CD2 4.46Å
424E96.8Very high96.7Very high69 Ų6949.1 Ų49.132%0.32225%0.245SC..SBendtrans-61.1-39.5176.9-67.8179.4-115.400111.8M420 K431 C432 R434 W436M420-E424 HydrophobicContact CE-CG 4.36Å; E424-K431 PolarHBondContact O-N 3.41Å; E424-C432 VanDerWaalsContact CA-O 3.32Å; E424-C432 WeakPolarHBondContact CA-O 3.4Å; E424-C432 WeakPolarHBondContact CB-O 3.44Å; E424-C432 PolarHBondContact O-N 2.89Å; E424-R434 VanDerWaalsContact OE2-CB 3.31Å; E424-R434 WeakPolarHBondContact OE2-CB 3.37Å; E424-R434 PolarHBondContact OE2-N 3.36Å; E424-W436 HydrophobicContact CG-CH2 4.29Å
425I96.2Very high96.7Very high110 Ų11045.9 Ų45.956%0.56423%0.23SC*.EExtended strand (participates in β ladder)trans-127.9130.9177.4-57.6174.8000108.6K423 K429K423-I425 VanDerWaalsContact C-N 3.26Å; K423-I425 PolarHBondContact O-N 3.04Å; I425-K429 WeakPolarHBondContact CA-O 3.17Å
426E93.8Very high96.7Very high13 Ų1346.3 Ų46.36%0.06123%0.231CC..EExtended strand (participates in β ladder)trans-129.6122.3170.7-64.2173.9-169.600107.4T422 K423 G428 K429 K431 R535T422-E426 PolarHBondContact OG1-OE1 2.91Å; K423-E426 HydrophobicContact CB-CG 4.01Å; K423-E426 PolarHBondContact N-OE1 2.97Å; K423-E426 VanDerWaalsContact N-OE1 3.08Å; E426-G428 VanDerWaalsContact C-N 3.35Å; E426-G428 PolarHBondContact O-N 3.38Å; E426-K429 PolarHBondContact N-O 3.48Å; E426-K429 PolarHBondContact O-N 3.49Å; E426-K429 VanDerWaalsContact O-N 3.07Å; E426-K431 HydrophobicContact CB-CD 4.45Å; E426-K431 HydrophobicContact CB-CG 3.85Å; E426-K431 HydrophobicContact CG-CG 3.87Å; E426-R535 IonicContact OE1-CZ 2.97Å; E426-R535 IonicContact OE1-NH1 3.46Å; E426-R535 PolarHBondContact OE1-NH1 3.49Å; E426-R535 IonicContact OE1-NH2 2.66Å; E426-R535 IonicContact OE2-CZ 3.92Å; E426-R535 IonicContact OE2-NH1 2.9Å; E426-R535 PolarHBondContact OE2-NH1 3.03Å; E426-R535 IonicContact OE2-NH2 3.93Å; E426-R535 PolarHBondContact OE2-NH2 3.23Å
427R90.1Very high96.7Very high151 Ų15143.3 Ų43.357%0.5722%0.22SC*.THydrogen-bonded Turntrans54.444.6-176.6-54.3-176.4171.2-162.8-2.8114.4K429 D495 H496R427-K429 PolarHBondContact O-N 3.12Å; R427-D495 VanDerWaalsContact CG-OD2 3.27Å; R427-D495 WeakPolarHBondContact CG-OD2 3.39Å; R427-D495 IonicContact NE-OD2 2.92Å; R427-H496 PolarHBondContact NH1-CE1 3.25Å; R427-H496 PolarHBondContact NH1-NE2 2.66Å; R427-H496 PolarHBondContact NH2-CD2 2.71Å; R427-H496 PolarHBondContact NH2-CE1 3.39Å; R427-H496 VanDerWaalsContact NH2-CG 3.35Å; R427-H496 PolarHBondContact NH2-NE2 3.1Å
428G92.9Very high96.6Very high73 Ų7347.4 Ų47.475%0.75324%0.239SC*.THydrogen-bonded Turntrans683.3-178.300000114.6E426E426-G428 VanDerWaalsContact C-N 3.35Å; E426-G428 PolarHBondContact O-N 3.38Å
429K94.6Very high96.3Very high145 Ų14550.1 Ų50.163%0.6326%0.262SS*.EExtended strand (participates in β ladder)trans-102.1129.5176.3-63.7-174.1-179.4-1780110I425 E426 R427 K431I425-K429 WeakPolarHBondContact CA-O 3.17Å; E426-K429 PolarHBondContact N-O 3.48Å; E426-K429 PolarHBondContact O-N 3.49Å; E426-K429 VanDerWaalsContact O-N 3.07Å; R427-K429 PolarHBondContact O-N 3.12Å; K429-K431 PolarHBondContact O-N 3.06Å
430S96.6Very high96Very high68 Ų6857.6 Ų57.648%0.47630%0.302SS..EExtended strand (participates in β ladder)trans-62.6124.1171.5176.70000110.5R289R289-S430 PolarHBondContact NH1-O 3.39Å
431K96.8Very high95.9Very high45 Ų4562.6 Ų62.620%0.19633%0.325CS..SBendtrans-106.2-31.8176.7-61.6-56.3-172.2173.50112.5R289 T422 K423 E424 E426 K429 S530R289-K431 PolarHBondContact NE-O 3.07Å; R289-K431 PolarHBondContact NH1-O 3.38Å; R289-K431 PolarHBondContact NH2-O 3.02Å; T422-K431 HydrophobicContact CG2-CB 4.18Å; T422-K431 WeakPolarHBondContact OG1-CB 3.38Å; K423-K431 WeakPolarHBondContact O-CB 3.24Å; E424-K431 PolarHBondContact O-N 3.41Å; E426-K431 HydrophobicContact CB-CD 4.45Å; E426-K431 HydrophobicContact CB-CG 3.85Å; E426-K431 HydrophobicContact CG-CG 3.87Å; K429-K431 PolarHBondContact O-N 3.06Å; K431-S530 WeakPolarHBondContact CA-OG 3.32Å; K431-S530 WeakPolarHBondContact O-CA 3.27Å; K431-S530 PolarHBondContact O-OG 3.08Å
432C98.2Very high95.8Very high1 Ų166.1 Ų66.11%0.00735%0.348CS..  trans-157.1139.5176.7-169.30000107.8C398 M420 T422 E424C398-C432 PolarHBondContact N-SG 3.34Å; M420-C432 HydrophobicContact CE-CB 3.74Å; T422-C432 HydrophobicContact CG2-CB 4.15Å; E424-C432 VanDerWaalsContact CA-O 3.32Å; E424-C432 WeakPolarHBondContact CA-O 3.4Å; E424-C432 WeakPolarHBondContact CB-O 3.44Å; E424-C432 PolarHBondContact O-N 2.89Å
433V98.1Very high95.8Very high37 Ų3768.8 Ų68.822%0.22436%0.364CS..  trans-79.3153.1166-52.90000109.4C398 V403 Y435C398-V433 HydrophobicContact CB-CG2 3.97Å; C398-V433 WeakPolarHBondContact O-CG2 3.46Å; C398-V433 PolarHBondContact O-N 3.28Å; V403-V433 HydrophobicContact CG2-CG2 3.78Å; V433-Y435 WeakPolarHBondContact O-CD1 3.3Å; V433-Y435 PolarHBondContact O-N 2.99Å
434R98.2Very high95.9Very high81 Ų8168.6 Ų68.631%0.30637%0.371SS..  trans-59.7120.4166.4-148.9166.28092.1-6.6109.6E424 W436 P437 E438E424-R434 VanDerWaalsContact OE2-CB 3.31Å; E424-R434 WeakPolarHBondContact OE2-CB 3.37Å; E424-R434 PolarHBondContact OE2-N 3.36Å; R434-W436 HydrophobicContact CG-CD2 3.88Å; R434-W436 HydrophobicContact CG-CE3 4.32Å; R434-W436 HydrophobicContact CG-CG 4.35Å; R434-W436 HydrophobicContact CG-CH2 4.19Å; R434-W436 HydrophobicContact CG-CZ2 3.74Å; R434-W436 HydrophobicContact CG-CZ3 4.45Å; R434-W436 VanDerWaalsContact CZ-O 3.22Å; R434-W436 PolarHBondContact NH1-O 3.4Å; R434-P437 PolarHBondContact NH1-O 3.29Å; R434-E438 IonicContact CZ-OE1 2.71Å; R434-E438 IonicContact NE-OE1 3.13Å; R434-E438 VanDerWaalsContact NH2-CD 3.27Å; R434-E438 VanDerWaalsContact NH2-N 3.18Å; R434-E438 IonicContact NH2-OE1 2.69Å; R434-E438 PolarHBondContact NH2-OE1 3.03Å
435Y98.2Very high95.9Very high6 Ų665.5 Ų65.52%0.02436%0.356CS..  trans-114.61.8177.360.1-95.1000112.4C398 F406 W407 I418 M420 V433 H487 H528C398-Y435 HydrophobicContact CB-CD1 3.95Å; C398-Y435 HydrophobicContact CB-CG 4.38Å; F406-Y435 AromaticContact CD1-CD2 3.85Å; F406-Y435 HydrophobicContact CD1-CD2 3.85Å; F406-Y435 HydrophobicContact CD1-CE2 4.17Å; F406-Y435 HydrophobicContact CD1-CG 4.36Å; F406-Y435 AromaticContact CE1-CD2 3.5Å; F406-Y435 HydrophobicContact CE1-CD2 3.5Å; F406-Y435 AromaticContact CE1-CE2 3.35Å; F406-Y435 HydrophobicContact CE1-CE2 3.35Å; F406-Y435 HydrophobicContact CE1-CG 4.31Å; F406-Y435 HydrophobicContact CZ-CD2 4.3Å; F406-Y435 AromaticContact CZ-CE2 3.79Å; F406-Y435 HydrophobicContact CZ-CE2 3.79Å; W407-Y435 AromaticContact CE2-CD2 3.97Å; W407-Y435 AromaticContact CZ2-CD2 3.69Å; W407-Y435 HydrophobicContact CZ2-CD2 3.69Å; W407-Y435 HydrophobicContact CZ2-CE2 4.09Å; W407-Y435 AromaticContact NE1-CD2 3.95Å; W407-Y435 PolarHBondContact NE1-O 3.04Å; I418-Y435 WeakPolarHBondContact CG2-OH 3.47Å; M420-Y435 HydrophobicContact SD-CE1 4.18Å; V433-Y435 WeakPolarHBondContact O-CD1 3.3Å; V433-Y435 PolarHBondContact O-N 2.99Å; Y435-H487 AromaticContact CZ-CD2 3.98Å; Y435-H487 AromaticContact CZ-NE2 3.59Å; Y435-H487 PolarHBondContact OH-CD2 3.1Å; Y435-H487 PolarHBondContact OH-NE2 2.81Å; Y435-H528 AromaticContact CE1-CE1 3.77Å; Y435-H528 AromaticContact CE1-NE2 3.67Å; Y435-H528 AromaticContact CZ-NE2 3.63Å; Y435-H528 PolarHBondContact OH-NE2 3.03Å
436W98.1Very high95.8Very high11 Ų1160.3 Ų60.34%0.04233%0.33CS..SBendtrans-109.4156174.359.792.1000110.5M420 E424 R434 L469 H487M420-W436 HydrophobicContact CE-CH2 3.92Å; M420-W436 HydrophobicContact CE-CZ3 4.16Å; M420-W436 HydrophobicContact SD-CH2 3.62Å; M420-W436 HydrophobicContact SD-CZ3 3.54Å; M420-W436 VanDerWaalsContact SD-CZ3 3.54Å; E424-W436 HydrophobicContact CG-CH2 4.29Å; R434-W436 HydrophobicContact CG-CD2 3.88Å; R434-W436 HydrophobicContact CG-CE3 4.32Å; R434-W436 HydrophobicContact CG-CG 4.35Å; R434-W436 HydrophobicContact CG-CH2 4.19Å; R434-W436 HydrophobicContact CG-CZ2 3.74Å; R434-W436 HydrophobicContact CG-CZ3 4.45Å; R434-W436 VanDerWaalsContact CZ-O 3.22Å; R434-W436 PolarHBondContact NH1-O 3.4Å; W436-L469 HydrophobicContact CB-CD1 4.21Å; W436-L469 HydrophobicContact CB-CD2 4.35Å; W436-H487 AromaticContact CE3-CE1 3.76Å; W436-H487 AromaticContact CE3-NE2 3.99Å; W436-H487 AromaticContact CZ3-CE1 3.76Å; W436-H487 AromaticContact CZ3-NE2 3.97Å
437P97.4Very high95.8Very high1 Ų160.4 Ų60.41%0.00633%0.33CS..PPolyproline II helixtrans-74163.3-179.929.2-37000112.4R434 Q441 T443 L453 L455R434-P437 PolarHBondContact NH1-O 3.29Å; P437-Q441 WeakPolarHBondContact CB-O 3.5Å; P437-T443 HydrophobicContact CB-CG2 4.06Å; P437-L453 VanDerWaalsContact CD-CG 3.5Å; P437-L453 HydrophobicContact CG-CD2 4.33Å; P437-L453 HydrophobicContact CG-CG 3.93Å; P437-L455 HydrophobicContact CG-CB 4.16Å
438E95.4Very high95.9Very high90 Ų9061.7 Ų61.742%0.42134%0.335SS..BIsolated β-bridgetrans-79.9163.6166.8-106.8155-114.500110.7R434 N440 Q441R434-E438 IonicContact CZ-OE1 2.71Å; R434-E438 IonicContact NE-OE1 3.13Å; R434-E438 VanDerWaalsContact NH2-CD 3.27Å; R434-E438 VanDerWaalsContact NH2-N 3.18Å; R434-E438 IonicContact NH2-OE1 2.69Å; R434-E438 PolarHBondContact NH2-OE1 3.03Å; E438-N440 PolarHBondContact O-N 3.4Å; E438-Q441 HydrophobicContact CB-CB 4.13Å; E438-Q441 HydrophobicContact CB-CG 4.28Å; E438-Q441 PolarHBondContact O-N 3.41Å; E438-Q441 VanDerWaalsContact O-N 3.15Å; E438-Q441 PolarHBondContact OE2-NE2 3.16Å; E438-Q441 VanDerWaalsContact OE2-NE2 3.14Å
439A93.1Very high95.9Very high58 Ų5863 Ų6348%0.47932%0.32SS..THydrogen-bonded Turntrans-57.4135.1172.800000109.8Q441 L455A439-Q441 PolarHBondContact O-N 3.13Å; A439-Q441 VanDerWaalsContact O-N 3.14Å; A439-L455 HydrophobicContact CB-CD2 4.23Å
440N92.6Very high95.8Very high161 Ų16158.9 Ų58.986%0.86130%0.303SS*.THydrogen-bonded Turntrans60.815.4-178.7-50-46.1000115.4E438E438-N440 PolarHBondContact O-N 3.4Å
441Q96.2Very high95.8Very high105 Ų10555.7 Ų55.749%0.49128%0.28SS..BIsolated β-bridgetrans-126.177176.9-64.3179.321.300111.2P437 E438 A439P437-Q441 WeakPolarHBondContact CB-O 3.5Å; E438-Q441 HydrophobicContact CB-CB 4.13Å; E438-Q441 HydrophobicContact CB-CG 4.28Å; E438-Q441 PolarHBondContact O-N 3.41Å; E438-Q441 VanDerWaalsContact O-N 3.15Å; E438-Q441 PolarHBondContact OE2-NE2 3.16Å; E438-Q441 VanDerWaalsContact OE2-NE2 3.14Å; A439-Q441 PolarHBondContact O-N 3.13Å; A439-Q441 VanDerWaalsContact O-N 3.14Å
442P95.8Very high95.8Very high73 Ų7358 Ų5847%0.47429%0.29SS..  trans-59.5141.1176.6-20.132.2000111.7L453 T454P442-L453 WeakPolarHBondContact CA-O 3.27Å; P442-T454 HydrophobicContact CG-CG2 4.32Å
443T97Very high95.8Very high58 Ų5857.9 Ų57.936%0.35629%0.29SS..EExtended strand (participates in β ladder)trans-122.6154179.8560000111.1P437 L453P437-T443 HydrophobicContact CB-CG2 4.06Å; T443-L453 PolarHBondContact N-O 2.89Å; T443-L453 PolarHBondContact O-N 3.3Å
444T97.2Very high95.8Very high85 Ų8558 Ų5852%0.52129%0.291SS..EExtended strand (participates in β ladder)trans-104.4141.7170.454.60000111.1I451T444-I451 CarbonylContact C-O 3.58Å; T444-I451 VanDerWaalsContact CA-O 3.32Å; T444-I451 WeakPolarHBondContact CA-O 3.1Å
445T96.7Very high95.8Very high3 Ų355.3 Ų55.32%0.01828%0.282CS..EExtended strand (participates in β ladder)trans-153.2-177-171.7-169.60000110.8D404 W407 K449 E450 I451 L453D404-T445 VanDerWaalsContact OD1-CA 3.28Å; D404-T445 WeakPolarHBondContact OD1-CA 3.26Å; D404-T445 PolarHBondContact OD1-OG1 3.4Å; W407-T445 HydrophobicContact CB-CG2 3.53Å; W407-T445 HydrophobicContact CD2-CG2 4.32Å; W407-T445 HydrophobicContact CG-CG2 3.51Å; T445-K449 CarbonylContact O-C 3.52Å; T445-K449 VanDerWaalsContact O-C 3.27Å; T445-K449 VanDerWaalsContact O-CA 3.3Å; T445-K449 WeakPolarHBondContact O-CA 3.33Å; T445-E450 PolarHBondContact O-N 2.92Å; T445-I451 HydrophobicContact CG2-CB 3.92Å; T445-I451 HydrophobicContact CG2-CG2 3.97Å; T445-I451 PolarHBondContact N-O 3.25Å; T445-I451 WeakPolarHBondContact O-CB 3.37Å; T445-I451 PolarHBondContact O-N 3.19Å; T445-L453 HydrophobicContact CG2-CB 4.44Å
446G95.1Very high95.8Very high1 Ų159 Ų591%0.0131%0.305CS..SBendtrans78.2-179-177.200000111.9D404 R448 K449D404-G446 WeakPolarHBondContact O-CA 3.25Å; D404-G446 PolarHBondContact OD1-N 3.48Å; D404-G446 VanDerWaalsContact OD1-N 3.1Å; G446-R448 PolarHBondContact O-N 3.16Å; G446-K449 PolarHBondContact O-N 2.86Å; G446-K449 VanDerWaalsContact O-N 3.09Å
447F92.9Very high95.8Very high16 Ų1660.9 Ų60.97%0.0732%0.323CS..G310 helixtrans-60.3135.5177.5-62.8-35.3000110.9L303 R304 N305 G306 S313 D405 E408 K449 E450L303-F447 HydrophobicContact CB-CE2 4.17Å; L303-F447 HydrophobicContact CB-CZ 3.88Å; L303-F447 HydrophobicContact CD1-CE1 4.33Å; L303-F447 HydrophobicContact CD1-CZ 3.72Å; L303-F447 HydrophobicContact CG-CZ 4.43Å; R304-F447 WeakPolarHBondContact O-CE2 3.07Å; N305-F447 WeakPolarHBondContact O-CD2 3.3Å; G306-F447 VanDerWaalsContact N-CE2 3.29Å; S313-F447 WeakPolarHBondContact O-CZ 3.3Å; D405-F447 WeakPolarHBondContact OD1-CE1 3.45Å; E408-F447 HydrophobicContact CB-CD2 4.33Å; E408-F447 HydrophobicContact CB-CE2 4.24Å; E408-F447 HydrophobicContact CB-CZ 4.39Å; E408-F447 HydrophobicContact CG-CD2 3.53Å; E408-F447 HydrophobicContact CG-CE2 3.51Å; E408-F447 HydrophobicContact CG-CG 4.2Å; E408-F447 HydrophobicContact CG-CZ 4.14Å; E408-F447 PolarHBondContact OE2-N 3.46Å; E408-F447 VanDerWaalsContact OE2-N 3.07Å; F447-K449 PolarHBondContact O-N 3.01Å; F447-E450 PolarHBondContact O-N 3.02Å
448R92Very high95.8Very high177 Ų17765.6 Ų65.667%0.66835%0.345SS*.G310 helixtrans54.518.6-177.3-54.5170.6-65.7-165.13.9114.1G446 E450G446-R448 PolarHBondContact O-N 3.16Å; R448-E450 VanDerWaalsContact C-N 3.28Å; R448-E450 HydrophobicContact CB-CG 4.1Å; R448-E450 IonicContact CZ-OE1 3.09Å; R448-E450 IonicContact CZ-OE2 3.02Å; R448-E450 IonicContact NE-OE1 3.51Å; R448-E450 PolarHBondContact NE-OE1 3.22Å; R448-E450 IonicContact NE-OE2 3.71Å; R448-E450 VanDerWaalsContact NH2-CD 3.31Å; R448-E450 IonicContact NH2-OE1 2.98Å; R448-E450 PolarHBondContact NH2-OE1 2.62Å; R448-E450 IonicContact NH2-OE2 3.97Å; R448-E450 PolarHBondContact NH2-OE2 3.35Å; R448-E450 PolarHBondContact O-N 2.85Å
449K93.7Very high95.9Very high101 Ų10167.2 Ų67.244%0.43935%0.347SS..G310 helixtrans60.431.7-178.8-55.4-64.9-179.8-179.20114.2D404 T445 G446 F447D404-K449 IonicContact OD1-NZ 3.98Å; D404-K449 PolarHBondContact OD1-NZ 2.95Å; D404-K449 WeakPolarHBondContact OD2-CE 3.31Å; D404-K449 IonicContact OD2-NZ 2.62Å; D404-K449 PolarHBondContact OD2-NZ 3.09Å; T445-K449 CarbonylContact O-C 3.52Å; T445-K449 VanDerWaalsContact O-C 3.27Å; T445-K449 VanDerWaalsContact O-CA 3.3Å; T445-K449 WeakPolarHBondContact O-CA 3.33Å; G446-K449 PolarHBondContact O-N 2.86Å; G446-K449 VanDerWaalsContact O-N 3.09Å; F447-K449 PolarHBondContact O-N 3.01Å
450E93.3Very high96Very high59 Ų5969 Ų6928%0.27635%0.352SS..  trans-80-12.4-175.4-70.3175169.100114.7T445 F447 R448 K473T445-E450 PolarHBondContact O-N 2.92Å; F447-E450 PolarHBondContact O-N 3.02Å; R448-E450 VanDerWaalsContact C-N 3.28Å; R448-E450 HydrophobicContact CB-CG 4.1Å; R448-E450 IonicContact CZ-OE1 3.09Å; R448-E450 IonicContact CZ-OE2 3.02Å; R448-E450 IonicContact NE-OE1 3.51Å; R448-E450 PolarHBondContact NE-OE1 3.22Å; R448-E450 IonicContact NE-OE2 3.71Å; R448-E450 VanDerWaalsContact NH2-CD 3.31Å; R448-E450 IonicContact NH2-OE1 2.98Å; R448-E450 PolarHBondContact NH2-OE1 2.62Å; R448-E450 IonicContact NH2-OE2 3.97Å; R448-E450 PolarHBondContact NH2-OE2 3.35Å; R448-E450 PolarHBondContact O-N 2.85Å; E450-K473 HydrophobicContact CB-CG 4.38Å
451I96Very high96.1Very high0 Ų064.7 Ų64.70%033%0.329CS..EExtended strand (participates in β ladder)trans-97.6116.8179.3-57.7172.9000108.6W407 W411 T444 T445 L471 K473W407-I451 HydrophobicContact CB-CD1 4.44Å; W411-I451 HydrophobicContact CB-CD1 3.77Å; W411-I451 HydrophobicContact CG-CD1 4.15Å; T444-I451 CarbonylContact C-O 3.58Å; T444-I451 VanDerWaalsContact CA-O 3.32Å; T444-I451 WeakPolarHBondContact CA-O 3.1Å; T445-I451 HydrophobicContact CG2-CB 3.92Å; T445-I451 HydrophobicContact CG2-CG2 3.97Å; T445-I451 PolarHBondContact N-O 3.25Å; T445-I451 WeakPolarHBondContact O-CB 3.37Å; T445-I451 PolarHBondContact O-N 3.19Å; I451-L471 HydrophobicContact CG2-CB 4.45Å; I451-L471 HydrophobicContact CG2-CG 4.46Å; I451-K473 HydrophobicContact CG1-CB 4.4Å; I451-K473 HydrophobicContact CG1-CD 3.92Å; I451-K473 HydrophobicContact CG1-CG 4.07Å
452K96.9Very high95.9Very high93 Ų9364.8 Ų64.840%0.40434%0.341SS..EExtended strand (participates in β ladder)trans-87129169.4-176.3179.7179.2-179.50109.5L471 S472 W480K452-L471 CarbonylContact O-C 3.48Å; K452-L471 WeakPolarHBondContact O-CA 3.37Å; K452-S472 PolarHBondContact N-O 2.79Å; K452-S472 PolarHBondContact O-N 3.21Å; K452-W480 HydrophobicContact CB-CZ3 4.35Å
453L97.9Very high95.8Very high0 Ų063.7 Ų63.70%033%0.331CS..EExtended strand (participates in β ladder)trans-120.1125.9-177.6-175.763.6000110.1W407 P437 P442 T443 T445 L469 C470 L471W407-L453 HydrophobicContact CD2-CD2 4.09Å; W407-L453 HydrophobicContact CH2-CD1 3.85Å; W407-L453 HydrophobicContact CH2-CD2 4.01Å; W407-L453 HydrophobicContact CZ2-CD1 4.03Å; W407-L453 HydrophobicContact CZ2-CD2 3.3Å; W407-L453 HydrophobicContact CZ2-CG 4.32Å; W407-L453 HydrophobicContact CZ3-CD1 4.1Å; P437-L453 VanDerWaalsContact CD-CG 3.5Å; P437-L453 HydrophobicContact CG-CD2 4.33Å; P437-L453 HydrophobicContact CG-CG 3.93Å; P442-L453 WeakPolarHBondContact CA-O 3.27Å; T443-L453 PolarHBondContact N-O 2.89Å; T443-L453 PolarHBondContact O-N 3.3Å; T445-L453 HydrophobicContact CG2-CB 4.44Å; L453-L469 HydrophobicContact CD1-CB 3.98Å; L453-L469 HydrophobicContact CD1-CD1 4.36Å; L453-C470 WeakPolarHBondContact CA-O 3.43Å; L453-L471 HydrophobicContact CD1-CD1 3.48Å; L453-L471 VanDerWaalsContact CD1-CD1 3.48Å; L453-L471 HydrophobicContact CD1-CG 3.88Å
454T97.8Very high95.8Very high39 Ų3961.3 Ų61.324%0.23932%0.316CS..EExtended strand (participates in β ladder)trans-130.9133.4-178.9-52.40000110.7P442 L469 C470P442-T454 HydrophobicContact CG-CG2 4.32Å; T454-L469 CarbonylContact O-C 3.27Å; T454-L469 WeakPolarHBondContact O-CA 3.11Å; T454-C470 PolarHBondContact N-O 2.82Å; T454-C470 PolarHBondContact O-N 2.86Å
455L98.4Very high95.9Very high24 Ų2457.4 Ų57.413%0.12629%0.292CS..EExtended strand (participates in β ladder)trans-79.5119.5170.2179.862.2000109.5P437 A439 A457 R467 L469P437-L455 HydrophobicContact CG-CB 4.16Å; A439-L455 HydrophobicContact CB-CD2 4.23Å; L455-A457 WeakPolarHBondContact CD1-O 3.3Å; L455-R467 HydrophobicContact CD1-CB 3.73Å; L455-R467 HydrophobicContact CD1-CG 4.04Å; L455-L469 HydrophobicContact CB-CD2 4.28Å; L455-L469 HydrophobicContact CD1-CD2 3.72Å
456V97.7Very high95.9Very high84 Ų8457.4 Ų57.451%0.50929%0.292SS..EExtended strand (participates in β ladder)trans-98.1-42.4-176.8178.90000111.4T468 C470 F484V456-T468 HydrophobicContact CB-CG2 4.41Å; V456-T468 WeakPolarHBondContact CB-O 3.24Å; V456-T468 PolarHBondContact N-O 2.81Å; V456-C470 HydrophobicContact CG2-CB 3.74Å; V456-F484 HydrophobicContact CG2-CE1 4.21Å
457A97.7Very high96.1Very high50 Ų5058.6 Ų58.641%0.41330%0.296SS..EExtended strand (participates in β ladder)trans-150.8150.8179.300000110.3L455 R467 T468L455-A457 WeakPolarHBondContact CD1-O 3.3Å; A457-R467 CarbonylContact O-C 3.52Å; A457-R467 WeakPolarHBondContact O-CA 3.42Å; A457-T468 PolarHBondContact N-O 3.49Å; A457-T468 PolarHBondContact O-N 3.28Å
458E97.9Very high96.4Very high101 Ų10159.2 Ų59.247%0.47230%0.302SS..EExtended strand (participates in β ladder)trans-136.7134.1172.1-178.8171.6-128.700108.8V460 V466 R467E458-V460 HydrophobicContact CG-CG2 4.13Å; E458-V466 CarbonylContact C-O 3.58Å; E458-V466 WeakPolarHBondContact CA-O 3.24Å; E458-R467 HydrophobicContact CB-CG 4.31Å; E458-R467 HydrophobicContact CG-CG 3.97Å; E458-R467 IonicContact OE1-CZ 3.15Å; E458-R467 IonicContact OE1-NE 3.95Å; E458-R467 PolarHBondContact OE1-NE 2.89Å; E458-R467 IonicContact OE1-NH2 2.82Å; E458-R467 PolarHBondContact OE1-NH2 3.02Å
459R97Very high96.7Very high124 Ų12450.8 Ų50.847%0.46827%0.27SS..EExtended strand (participates in β ladder)trans-124.4142.9167.462.4172.5-178.8-117.7-1.5109.2A465 V466 Y488 E511R459-A465 CarbonylContact O-C 3.59Å; R459-A465 VanDerWaalsContact O-CA 3.28Å; R459-A465 WeakPolarHBondContact O-CA 3.47Å; R459-V466 HydrophobicContact CG-CB 3.66Å; R459-V466 HydrophobicContact CG-CG2 4.12Å; R459-V466 PolarHBondContact N-O 3.04Å; R459-V466 PolarHBondContact O-N 2.87Å; R459-Y488 PolarHBondContact NH2-OH 3.38Å; R459-E511 IonicContact CZ-OE1 3.34Å; R459-E511 IonicContact NE-OE1 3.87Å; R459-E511 IonicContact NH2-OE1 2.7Å; R459-E511 PolarHBondContact NH2-OE1 3.02Å
460V96.6Very high96.9Very high95 Ų9547 Ų4758%0.57626%0.256SS*.EExtended strand (participates in β ladder)trans-132.9130.5177.8-1720000108.4E458 A465 L491E458-V460 HydrophobicContact CG-CG2 4.13Å; V460-A465 HydrophobicContact CB-CB 4.45Å; V460-A465 HydrophobicContact CG1-CB 4.29Å; V460-A465 HydrophobicContact CG2-CB 3.89Å; V460-L491 HydrophobicContact CG1-CD1 4.4Å
461N94Very high97.1Very high70 Ų7044.3 Ų44.337%0.37424%0.243SC..  trans-119.5-172.6168.968.431.5000109.9D463 F464N461-D463 PolarHBondContact O-N 3.08Å; N461-D463 PolarHBondContact OD1-N 3.38Å; N461-F464 PolarHBondContact N-O 2.82Å; N461-F464 WeakPolarHBondContact ND2-CE1 3.48Å; N461-F464 WeakPolarHBondContact ND2-CE2 3.44Å; N461-F464 WeakPolarHBondContact ND2-CZ 3.49Å; N461-F464 WeakPolarHBondContact OD1-CD1 3.23Å; N461-F464 PolarHBondContact OD1-N 3.24Å; N461-F464 PolarHBondContact OD1-O 3.44Å; N461-F464 VanDerWaalsContact OD1-O 3.04Å
462S91.5Very high97.1Very high108 Ų10845.1 Ų45.176%0.75525%0.249SC*.SBendtrans-62.5-28.9-178.153.80000113.9
463D94.8Very high97Very high49 Ų4941.7 Ų41.726%0.26223%0.234SC..SBendtrans-103.8-33.1-170.2-67.4-29.1000113.1N461 L491 A492N461-D463 PolarHBondContact O-N 3.08Å; N461-D463 PolarHBondContact OD1-N 3.38Å; D463-L491 WeakPolarHBondContact O-CA 3.17Å; D463-L491 PolarHBondContact O-N 3.48Å; D463-A492 HydrophobicContact CB-CB 4.18Å; D463-A492 PolarHBondContact O-N 3.41Å
464F97.1Very high96.5Very high9 Ų948.8 Ų48.84%0.03926%0.261CS..EExtended strand (participates in β ladder)trans-156.4159.8-173.959.3-90.2000113.5N461 V466 H489 F490 F508 E511N461-F464 PolarHBondContact N-O 2.82Å; N461-F464 WeakPolarHBondContact ND2-CE1 3.48Å; N461-F464 WeakPolarHBondContact ND2-CE2 3.44Å; N461-F464 WeakPolarHBondContact ND2-CZ 3.49Å; N461-F464 WeakPolarHBondContact OD1-CD1 3.23Å; N461-F464 PolarHBondContact OD1-N 3.24Å; N461-F464 PolarHBondContact OD1-O 3.44Å; N461-F464 VanDerWaalsContact OD1-O 3.04Å; F464-V466 HydrophobicContact CD2-CG2 3.56Å; F464-V466 HydrophobicContact CE2-CG2 3.59Å; F464-H489 CarbonylContact C-O 3.37Å; F464-H489 WeakPolarHBondContact CA-O 3.48Å; F464-H489 VanDerWaalsContact CB-O 3.23Å; F464-H489 WeakPolarHBondContact CB-O 3.43Å; F464-F490 HydrophobicContact CB-CD2 4.33Å; F464-F508 HydrophobicContact CB-CD2 3.78Å; F464-F508 HydrophobicContact CB-CE2 3.76Å; F464-F508 HydrophobicContact CD1-CB 4.32Å; F464-F508 AromaticContact CD1-CD2 3.57Å; F464-F508 HydrophobicContact CD1-CD2 3.57Å; F464-F508 HydrophobicContact CD1-CE2 4.38Å; F464-F508 HydrophobicContact CD1-CG 4.41Å; F464-F508 AromaticContact CD2-CD2 3.9Å; F464-F508 HydrophobicContact CD2-CD2 3.9Å; F464-F508 HydrophobicContact CD2-CE2 4.11Å; F464-F508 HydrophobicContact CE1-CB 4.33Å; F464-F508 HydrophobicContact CE1-CD2 4.04Å; F464-F508 HydrophobicContact CE2-CD2 4.33Å; F464-F508 AromaticContact CG-CD2 3.49Å; F464-F508 HydrophobicContact CG-CD2 3.49Å; F464-F508 VanDerWaalsContact CG-CD2 3.49Å; F464-F508 AromaticContact CG-CE2 3.86Å; F464-F508 HydrophobicContact CG-CE2 3.86Å; F464-F508 HydrophobicContact CZ-CD2 4.39Å; F464-E511 WeakPolarHBondContact CE2-OE1 3.43Å; F464-E511 VanDerWaalsContact CZ-OE2 3.3Å; F464-E511 WeakPolarHBondContact CZ-OE2 3.33Å
465A97.9Very high95.9Very high2 Ų253.1 Ų53.12%0.01727%0.273CS..EExtended strand (participates in β ladder)trans-107.6147.3167.200000110.2R459 V460 H489 L491R459-A465 CarbonylContact O-C 3.59Å; R459-A465 VanDerWaalsContact O-CA 3.28Å; R459-A465 WeakPolarHBondContact O-CA 3.47Å; V460-A465 HydrophobicContact CB-CB 4.45Å; V460-A465 HydrophobicContact CG1-CB 4.29Å; V460-A465 HydrophobicContact CG2-CB 3.89Å; A465-H489 HydrophobicContact CB-CB 4.32Å; A465-H489 PolarHBondContact N-O 3.27Å; A465-H489 PolarHBondContact O-N 3.3Å; A465-L491 HydrophobicContact CB-CD1 4.16Å
466V98.4Very high95.1Very high4 Ų460.4 Ų60.42%0.02431%0.312CS..EExtended strand (participates in β ladder)trans-127127.1172.4-170.10000109E458 R459 F464 H487 Y488E458-V466 CarbonylContact C-O 3.58Å; E458-V466 WeakPolarHBondContact CA-O 3.24Å; R459-V466 HydrophobicContact CG-CB 3.66Å; R459-V466 HydrophobicContact CG-CG2 4.12Å; R459-V466 PolarHBondContact N-O 3.04Å; R459-V466 PolarHBondContact O-N 2.87Å; F464-V466 HydrophobicContact CD2-CG2 3.56Å; F464-V466 HydrophobicContact CE2-CG2 3.59Å; V466-H487 CarbonylContact C-O 3.58Å; V466-H487 VanDerWaalsContact CA-O 3.32Å; V466-H487 WeakPolarHBondContact CA-O 3.47Å; V466-Y488 HydrophobicContact CB-CD1 4.49Å; V466-Y488 HydrophobicContact CB-CE1 4.43Å; V466-Y488 HydrophobicContact CG1-CD1 4.2Å; V466-Y488 HydrophobicContact CG1-CD2 4.17Å; V466-Y488 HydrophobicContact CG1-CE1 3.97Å; V466-Y488 HydrophobicContact CG1-CE2 3.93Å; V466-Y488 HydrophobicContact CG1-CG 4.29Å; V466-Y488 HydrophobicContact CG2-CD1 3.57Å; V466-Y488 HydrophobicContact CG2-CE1 3.55Å; V466-Y488 HydrophobicContact CG2-CG 4.29Å
467R98.5Very high94.6Very high25 Ų2561 Ų619%0.09431%0.312CS..EExtended strand (participates in β ladder)trans-115.9134.1176.2-60176.1-176.7959.1110.1L455 A457 E458 L469 H487 H489L455-R467 HydrophobicContact CD1-CB 3.73Å; L455-R467 HydrophobicContact CD1-CG 4.04Å; A457-R467 CarbonylContact O-C 3.52Å; A457-R467 WeakPolarHBondContact O-CA 3.42Å; E458-R467 HydrophobicContact CB-CG 4.31Å; E458-R467 HydrophobicContact CG-CG 3.97Å; E458-R467 IonicContact OE1-CZ 3.15Å; E458-R467 IonicContact OE1-NE 3.95Å; E458-R467 PolarHBondContact OE1-NE 2.89Å; E458-R467 IonicContact OE1-NH2 2.82Å; E458-R467 PolarHBondContact OE1-NH2 3.02Å; R467-L469 HydrophobicContact CB-CD2 4.4Å; R467-H487 HydrophobicContact CB-CB 4.16Å; R467-H487 PolarHBondContact N-O 3.48Å; R467-H487 PolarHBondContact NH1-CE1 3.3Å; R467-H487 VanDerWaalsContact NH1-CE1 3.28Å; R467-H487 PolarHBondContact NH1-ND1 3.33Å; R467-H487 PolarHBondContact O-N 2.9Å; R467-H489 PolarHBondContact NH1-ND1 2.77Å
468T98.3Very high93.8Very high29 Ų2965.8 Ų65.818%0.17833%0.326CS..EExtended strand (participates in β ladder)trans-97.6117.3168.9-56.50000108V456 A457 F484 Y486V456-T468 HydrophobicContact CB-CG2 4.41Å; V456-T468 WeakPolarHBondContact CB-O 3.24Å; V456-T468 PolarHBondContact N-O 2.81Å; A457-T468 PolarHBondContact N-O 3.49Å; A457-T468 PolarHBondContact O-N 3.28Å; T468-F484 HydrophobicContact CG2-CD1 3.87Å; T468-Y486 HydrophobicContact CG2-CD1 4.35Å; T468-Y486 HydrophobicContact CG2-CE1 4.09Å
469L98.5Very high93.4Very high0 Ų063 Ų630%032%0.318CS..EExtended strand (participates in β ladder)trans-109.7136.1-178-57.5173.7000109.4W407 W436 L453 T454 L455 R467 L471 F484 V485 H487W407-L469 HydrophobicContact CH2-CD1 3.56Å; W407-L469 HydrophobicContact CZ2-CD1 4.11Å; W436-L469 HydrophobicContact CB-CD1 4.21Å; W436-L469 HydrophobicContact CB-CD2 4.35Å; L453-L469 HydrophobicContact CD1-CB 3.98Å; L453-L469 HydrophobicContact CD1-CD1 4.36Å; T454-L469 CarbonylContact O-C 3.27Å; T454-L469 WeakPolarHBondContact O-CA 3.11Å; L455-L469 HydrophobicContact CB-CD2 4.28Å; L455-L469 HydrophobicContact CD1-CD2 3.72Å; R467-L469 HydrophobicContact CB-CD2 4.4Å; L469-L471 HydrophobicContact CB-CD1 4.06Å; L469-F484 CarbonylContact O-C 3.59Å; L469-F484 VanDerWaalsContact O-CA 3.29Å; L469-F484 WeakPolarHBondContact O-CA 3.41Å; L469-V485 HydrophobicContact CB-CB 4.46Å; L469-V485 PolarHBondContact N-O 3.08Å; L469-V485 PolarHBondContact O-N 3.34Å; L469-H487 HydrophobicContact CD1-CB 4.02Å
470C97.9Very high93.1Very high22 Ų2264.2 Ų64.215%0.14932%0.322CS..EExtended strand (participates in β ladder)trans-99.3118.2168.4-173.50000108.8L453 T454 V456 F484L453-C470 WeakPolarHBondContact CA-O 3.43Å; T454-C470 PolarHBondContact N-O 2.82Å; T454-C470 PolarHBondContact O-N 2.86Å; V456-C470 HydrophobicContact CG2-CB 3.74Å; C470-F484 HydrophobicContact CB-CD1 4.38Å; C470-F484 HydrophobicContact CB-CE1 4.21Å
471L97.7Very high93Very high2 Ų262.8 Ų62.81%0.0131%0.31CS..EExtended strand (participates in β ladder)trans-100.4125.6172.2-75.964.3000107.6W407 V410 W411 I451 K452 L453 L469 S482 R483 V485W407-L471 HydrophobicContact CE3-CD1 4.45Å; W407-L471 HydrophobicContact CE3-CD2 3.71Å; W407-L471 HydrophobicContact CE3-CG 4.16Å; W407-L471 HydrophobicContact CH2-CD1 4.39Å; W407-L471 HydrophobicContact CZ3-CD1 3.78Å; W407-L471 HydrophobicContact CZ3-CD2 3.72Å; W407-L471 HydrophobicContact CZ3-CG 3.99Å; V410-L471 HydrophobicContact CG1-CD2 3.84Å; W411-L471 HydrophobicContact CE3-CB 4.25Å; W411-L471 HydrophobicContact CE3-CD2 4.39Å; W411-L471 HydrophobicContact CZ3-CB 4.12Å; I451-L471 HydrophobicContact CG2-CB 4.45Å; I451-L471 HydrophobicContact CG2-CG 4.46Å; K452-L471 CarbonylContact O-C 3.48Å; K452-L471 WeakPolarHBondContact O-CA 3.37Å; L453-L471 HydrophobicContact CD1-CD1 3.48Å; L453-L471 VanDerWaalsContact CD1-CD1 3.48Å; L453-L471 HydrophobicContact CD1-CG 3.88Å; L469-L471 HydrophobicContact CB-CD1 4.06Å; L471-S482 CarbonylContact O-C 3.53Å; L471-S482 WeakPolarHBondContact O-CA 3.4Å; L471-R483 PolarHBondContact N-O 2.85Å; L471-R483 PolarHBondContact O-N 3.35Å; L471-V485 HydrophobicContact CD1-CB 3.67Å; L471-V485 HydrophobicContact CD1-CG2 3.48Å; L471-V485 VanDerWaalsContact CD1-CG2 3.48Å; L471-V485 HydrophobicContact CD2-CG2 3.76Å; L471-V485 HydrophobicContact CG-CG2 4.22Å
472S97.1Very high93.1Very high17 Ų1762.7 Ų62.712%0.11932%0.315CS..EExtended strand (participates in β ladder)trans-125.7127.4175-54.10000109.9K452 E481 S482K452-S472 PolarHBondContact N-O 2.79Å; K452-S472 PolarHBondContact O-N 3.21Å; S472-E481 CarbonylContact C-O 3.54Å; S472-E481 VanDerWaalsContact CA-O 3.23Å; S472-E481 WeakPolarHBondContact CA-O 3.41Å; S472-S482 WeakPolarHBondContact CB-OG 3.13Å; S472-S482 PolarHBondContact OG-OG 3.49Å
473K95Very high93.3Very high21 Ų2159 Ų599%0.09128%0.284CS..EExtended strand (participates in β ladder)trans-124.1139.4174.8-162.1176.8-174.4167.90109.4E408 W411 E450 I451 E481E408-K473 IonicContact OE1-NZ 2.95Å; E408-K473 PolarHBondContact OE1-NZ 3.45Å; E408-K473 IonicContact OE2-NZ 2.88Å; E408-K473 PolarHBondContact OE2-NZ 2.94Å; W411-K473 HydrophobicContact CD2-CB 4.04Å; W411-K473 HydrophobicContact CD2-CD 3.88Å; W411-K473 HydrophobicContact CE3-CB 4.04Å; W411-K473 HydrophobicContact CG-CD 4.07Å; W411-K473 HydrophobicContact CH2-CB 3.36Å; W411-K473 HydrophobicContact CZ2-CB 3.35Å; W411-K473 HydrophobicContact CZ2-CD 4.05Å; W411-K473 HydrophobicContact CZ2-CG 4.26Å; W411-K473 HydrophobicContact CZ3-CB 3.71Å; E450-K473 HydrophobicContact CB-CG 4.38Å; I451-K473 HydrophobicContact CG1-CB 4.4Å; I451-K473 HydrophobicContact CG1-CD 3.92Å; I451-K473 HydrophobicContact CG1-CG 4.07Å; K473-E481 PolarHBondContact N-O 3.31Å; K473-E481 PolarHBondContact O-N 3.15Å
474R86.6Confident93.4Very high150 Ų15061.2 Ų61.257%0.56629%0.292SS*.EExtended strand (participates in β ladder)trans-76.6132.5176.3-166.9176.465172.70.2110W480R474-W480 HydrophobicContact CB-CD2 4.47Å; R474-W480 HydrophobicContact CB-CE3 4.48Å; R474-W480 HydrophobicContact CB-CH2 4.47Å; R474-W480 HydrophobicContact CB-CZ2 4.42Å; R474-W480 HydrophobicContact CB-CZ3 4.49Å
475R84.9Confident93.5Very high130 Ų13060.9 Ų60.949%0.49129%0.29SS..  trans-85.9168.9174.7-6717974-144.88.5110.5D477 E478 S479 E481R475-D477 WeakPolarHBondContact CB-OD1 3.14Å; R475-D477 IonicContact CZ-OD2 2.79Å; R475-D477 IonicContact NH1-OD1 3.57Å; R475-D477 IonicContact NH1-OD2 3.38Å; R475-D477 PolarHBondContact NH1-OD2 2.62Å; R475-D477 PolarHBondContact O-N 2.71Å; R475-E478 PolarHBondContact O-N 3.4Å; R475-E478 VanDerWaalsContact O-N 3.1Å; R475-S479 WeakPolarHBondContact CB-O 3.2Å; R475-S479 WeakPolarHBondContact CD-OG 3.46Å; R475-S479 PolarHBondContact N-O 3.09Å; R475-S479 PolarHBondContact NH1-OG 3.05Å; R475-E481 HydrophobicContact CG-CB 4.2Å
476N81.9Confident93.5Very high177 Ų17763.4 Ų63.495%0.94730%0.3SS*.THydrogen-bonded Turntrans-64.5-26.4179-67.1-10.4000113E478N476-E478 PolarHBondContact O-N 3.31Å
477D87.3Confident93.5Very high96 Ų9663.2 Ų63.251%0.51330%0.299SS..THydrogen-bonded Turntrans-8416.5175.563.7-0.9000112.7R475 S479R475-D477 WeakPolarHBondContact CB-OD1 3.14Å; R475-D477 IonicContact CZ-OD2 2.79Å; R475-D477 IonicContact NH1-OD1 3.57Å; R475-D477 IonicContact NH1-OD2 3.38Å; R475-D477 PolarHBondContact NH1-OD2 2.62Å; R475-D477 PolarHBondContact O-N 2.71Å; D477-S479 PolarHBondContact O-N 2.79Å; D477-S479 VanDerWaalsContact OD1-CB 3.27Å; D477-S479 WeakPolarHBondContact OD1-CB 3.48Å; D477-S479 PolarHBondContact OD1-N 2.82Å; D477-S479 PolarHBondContact OD1-OG 2.86Å; D477-S479 PolarHBondContact OD2-OG 3.4Å
478E80.9Confident93.5Very high150 Ų15062.2 Ų62.270%0.70130%0.295SS*.SBendtrans62.1-1-174.7-52.8-168151.200115.7R475 N476R475-E478 PolarHBondContact O-N 3.4Å; R475-E478 VanDerWaalsContact O-N 3.1Å; N476-E478 PolarHBondContact O-N 3.31Å
479S89Confident93.5Very high43 Ų4361.2 Ų61.230%0.30129%0.288SS..PPolyproline II helixtrans-71.8155.4174.473.80000111.4R475 D477R475-S479 WeakPolarHBondContact CB-O 3.2Å; R475-S479 WeakPolarHBondContact CD-OG 3.46Å; R475-S479 PolarHBondContact N-O 3.09Å; R475-S479 PolarHBondContact NH1-OG 3.05Å; D477-S479 PolarHBondContact O-N 2.79Å; D477-S479 VanDerWaalsContact OD1-CB 3.27Å; D477-S479 WeakPolarHBondContact OD1-CB 3.48Å; D477-S479 PolarHBondContact OD1-N 2.82Å; D477-S479 PolarHBondContact OD1-OG 2.86Å; D477-S479 PolarHBondContact OD2-OG 3.4Å
480W90.5Very high93.5Very high149 Ų14961.3 Ų61.356%0.56429%0.288SS*.EExtended strand (participates in β ladder)trans-100.4124.9176.7-74.284.2000110.4K452 R474K452-W480 HydrophobicContact CB-CZ3 4.35Å; R474-W480 HydrophobicContact CB-CD2 4.47Å; R474-W480 HydrophobicContact CB-CE3 4.48Å; R474-W480 HydrophobicContact CB-CH2 4.47Å; R474-W480 HydrophobicContact CB-CZ2 4.42Å; R474-W480 HydrophobicContact CB-CZ3 4.49Å
481E95Very high93.4Very high66 Ų6662.6 Ų62.631%0.30829%0.293SS..EExtended strand (participates in β ladder)trans-92.8131.6165.6-172.1-177.6166.500108.6W411 S472 K473 R475 R483W411-E481 HydrophobicContact CH2-CB 3.9Å; W411-E481 HydrophobicContact CH2-CG 3.98Å; W411-E481 WeakPolarHBondContact CH2-O 3.09Å; W411-E481 HydrophobicContact CZ2-CB 4.1Å; W411-E481 HydrophobicContact CZ2-CG 4.2Å; S472-E481 CarbonylContact C-O 3.54Å; S472-E481 VanDerWaalsContact CA-O 3.23Å; S472-E481 WeakPolarHBondContact CA-O 3.41Å; K473-E481 PolarHBondContact N-O 3.31Å; K473-E481 PolarHBondContact O-N 3.15Å; R475-E481 HydrophobicContact CG-CB 4.2Å; E481-R483 IonicContact OE1-CZ 3.03Å; E481-R483 IonicContact OE1-NE 3.67Å; E481-R483 PolarHBondContact OE1-NE 2.99Å; E481-R483 IonicContact OE1-NH2 3.42Å; E481-R483 PolarHBondContact OE1-NH2 3.11Å; E481-R483 IonicContact OE2-NH2 3.23Å
482S96.2Very high93.3Very high68 Ų6864.1 Ų64.148%0.47631%0.306SS..EExtended strand (participates in β ladder)trans-126.1141.7177.9-62.70000112.3L471 S472L471-S482 CarbonylContact O-C 3.53Å; L471-S482 WeakPolarHBondContact O-CA 3.4Å; S472-S482 WeakPolarHBondContact CB-OG 3.13Å; S472-S482 PolarHBondContact OG-OG 3.49Å
483R95.9Very high93.2Very high30 Ų3063.5 Ų63.511%0.11330%0.302CS..EExtended strand (participates in β ladder)trans-137.9137.2-177-58.7177.9-173.2172.30.1109.9W411 L471 E481W411-R483 HydrophobicContact CH2-CG 4.45Å; W411-R483 HydrophobicContact CZ3-CG 4.34Å; W411-R483 PolarHBondContact O-NH1 3.17Å; L471-R483 PolarHBondContact N-O 2.85Å; L471-R483 PolarHBondContact O-N 3.35Å; E481-R483 IonicContact OE1-CZ 3.03Å; E481-R483 IonicContact OE1-NE 3.67Å; E481-R483 PolarHBondContact OE1-NE 2.99Å; E481-R483 IonicContact OE1-NH2 3.42Å; E481-R483 PolarHBondContact OE1-NH2 3.11Å; E481-R483 IonicContact OE2-NH2 3.23Å
484F97.4Very high93.1Very high96 Ų9664.6 Ų64.642%0.42131%0.311SS..EExtended strand (participates in β ladder)trans-88.1121.9171-70.6-72000111.3R416 V456 T468 L469 C470R416-F484 PolarHBondContact NE-O 3.25Å; R416-F484 PolarHBondContact NH2-O 3.33Å; V456-F484 HydrophobicContact CG2-CE1 4.21Å; T468-F484 HydrophobicContact CG2-CD1 3.87Å; L469-F484 CarbonylContact O-C 3.59Å; L469-F484 VanDerWaalsContact O-CA 3.29Å; L469-F484 WeakPolarHBondContact O-CA 3.41Å; C470-F484 HydrophobicContact CB-CD1 4.38Å; C470-F484 HydrophobicContact CB-CE1 4.21Å
485V98.3Very high92.6Very high2 Ų260.6 Ų60.61%0.01230%0.3CS..EExtended strand (participates in β ladder)trans-110131.5173.9174.50000109.3V410 R416 I418 L469 L471V410-V485 HydrophobicContact CG1-CG2 4.04Å; R416-V485 CarbonylContact O-C 3.55Å; R416-V485 WeakPolarHBondContact O-CA 3.02Å; I418-V485 HydrophobicContact CD1-CG1 3.58Å; I418-V485 HydrophobicContact CG1-CG1 3.87Å; L469-V485 HydrophobicContact CB-CB 4.46Å; L469-V485 PolarHBondContact N-O 3.08Å; L469-V485 PolarHBondContact O-N 3.34Å; L471-V485 HydrophobicContact CD1-CB 3.67Å; L471-V485 HydrophobicContact CD1-CG2 3.48Å; L471-V485 VanDerWaalsContact CD1-CG2 3.48Å; L471-V485 HydrophobicContact CD2-CG2 3.76Å; L471-V485 HydrophobicContact CG-CG2 4.22Å
486Y98.5Very high92.4Very high55 Ų5560.6 Ų60.622%0.21631%0.306CS..EExtended strand (participates in β ladder)trans-100.5112.9179.1-56.5-87000109.4R416 I417 I418 T468 L515 L519R416-Y486 PolarHBondContact O-N 3.1Å; I417-Y486 WeakPolarHBondContact CA-O 3.46Å; I418-Y486 PolarHBondContact N-O 3.37Å; T468-Y486 HydrophobicContact CG2-CD1 4.35Å; T468-Y486 HydrophobicContact CG2-CE1 4.09Å; Y486-L515 HydrophobicContact CD1-CD1 4.5Å; Y486-L515 HydrophobicContact CD1-CD2 4.08Å; Y486-L515 HydrophobicContact CD2-CD1 4.13Å; Y486-L515 HydrophobicContact CD2-CD2 3.63Å; Y486-L515 HydrophobicContact CD2-CG 4.32Å; Y486-L515 HydrophobicContact CE1-CD1 4.3Å; Y486-L515 HydrophobicContact CE2-CD1 3.92Å; Y486-L515 HydrophobicContact CE2-CD2 4.28Å; Y486-L515 HydrophobicContact CG-CD1 4.4Å; Y486-L515 HydrophobicContact CG-CD2 3.5Å; Y486-L515 VanDerWaalsContact CG-CD2 3.5Å; Y486-L519 HydrophobicContact CE2-CD2 4.15Å
487H98.7Very high92.8Very high0 Ų054.2 Ų54.20%028%0.282CS..EExtended strand (participates in β ladder)trans-99106179.9175.2-107.1000109.8I418 Y435 W436 V466 R467 L469I418-H487 CarbonylContact O-C 3.56Å; Y435-H487 AromaticContact CZ-CD2 3.98Å; Y435-H487 AromaticContact CZ-NE2 3.59Å; Y435-H487 PolarHBondContact OH-CD2 3.1Å; Y435-H487 PolarHBondContact OH-NE2 2.81Å; W436-H487 AromaticContact CE3-CE1 3.76Å; W436-H487 AromaticContact CE3-NE2 3.99Å; W436-H487 AromaticContact CZ3-CE1 3.76Å; W436-H487 AromaticContact CZ3-NE2 3.97Å; V466-H487 CarbonylContact C-O 3.58Å; V466-H487 VanDerWaalsContact CA-O 3.32Å; V466-H487 WeakPolarHBondContact CA-O 3.47Å; R467-H487 HydrophobicContact CB-CB 4.16Å; R467-H487 PolarHBondContact N-O 3.48Å; R467-H487 PolarHBondContact NH1-CE1 3.3Å; R467-H487 VanDerWaalsContact NH1-CE1 3.28Å; R467-H487 PolarHBondContact NH1-ND1 3.33Å; R467-H487 PolarHBondContact O-N 2.9Å; L469-H487 HydrophobicContact CD1-CB 4.02Å
488Y98.7Very high93.2Very high4 Ų451.4 Ų51.42%0.01627%0.269CS..EExtended strand (participates in β ladder)trans-94.8115.4176-78.1-99000109.8I417 I418 V419 M420 R459 V466 F508 E511 I512 L515I417-Y488 HydrophobicContact CG2-CD2 4.13Å; I417-Y488 HydrophobicContact CG2-CE2 4.49Å; I418-Y488 PolarHBondContact O-N 2.86Å; V419-Y488 CarbonylContact C-O 3.58Å; V419-Y488 WeakPolarHBondContact CA-O 3.2Å; M420-Y488 PolarHBondContact N-O 2.76Å; R459-Y488 PolarHBondContact NH2-OH 3.38Å; V466-Y488 HydrophobicContact CB-CD1 4.49Å; V466-Y488 HydrophobicContact CB-CE1 4.43Å; V466-Y488 HydrophobicContact CG1-CD1 4.2Å; V466-Y488 HydrophobicContact CG1-CD2 4.17Å; V466-Y488 HydrophobicContact CG1-CE1 3.97Å; V466-Y488 HydrophobicContact CG1-CE2 3.93Å; V466-Y488 HydrophobicContact CG1-CG 4.29Å; V466-Y488 HydrophobicContact CG2-CD1 3.57Å; V466-Y488 HydrophobicContact CG2-CE1 3.55Å; V466-Y488 HydrophobicContact CG2-CG 4.29Å; Y488-F508 HydrophobicContact CD1-CD2 4.36Å; Y488-F508 AromaticContact CD1-CE2 3.85Å; Y488-F508 HydrophobicContact CD1-CE2 3.85Å; Y488-F508 HydrophobicContact CD1-CZ 4.41Å; Y488-F508 HydrophobicContact CG-CE2 4.29Å; Y488-F508 HydrophobicContact CG-CZ 4.47Å; Y488-E511 HydrophobicContact CE1-CG 4.03Å; Y488-E511 WeakPolarHBondContact CE1-OE1 3.46Å; Y488-I512 HydrophobicContact CD1-CD1 4.17Å; Y488-I512 HydrophobicContact CD1-CG1 3.71Å; Y488-I512 HydrophobicContact CD2-CG1 4Å; Y488-I512 HydrophobicContact CE1-CG1 3.89Å; Y488-I512 HydrophobicContact CE2-CG1 4.17Å; Y488-I512 HydrophobicContact CG-CD1 4.1Å; Y488-I512 HydrophobicContact CG-CG1 3.78Å; Y488-L515 HydrophobicContact CE2-CD2 3.55Å
489H98.5Very high93.9Very high8 Ų844.6 Ų44.64%0.03724%0.237CC..EExtended strand (participates in β ladder)trans-112.9102-177.8-173.7178.5000110M420 T422 F464 A465 R467 L491M420-H489 HydrophobicContact CB-CB 4.42Å; M420-H489 CarbonylContact O-C 3.58Å; M420-H489 WeakPolarHBondContact O-CA 3.34Å; M420-H489 PolarHBondContact O-CD2 3.46Å; T422-H489 PolarHBondContact O-NE2 3.3Å; F464-H489 CarbonylContact C-O 3.37Å; F464-H489 WeakPolarHBondContact CA-O 3.48Å; F464-H489 VanDerWaalsContact CB-O 3.23Å; F464-H489 WeakPolarHBondContact CB-O 3.43Å; A465-H489 HydrophobicContact CB-CB 4.32Å; A465-H489 PolarHBondContact N-O 3.27Å; A465-H489 PolarHBondContact O-N 3.3Å; R467-H489 PolarHBondContact NH1-ND1 2.77Å; H489-L491 PolarHBondContact O-N 3.01Å
490F98.1Very high94Very high1 Ų147.6 Ų47.60%0.00427%0.265CS..EExtended strand (participates in β ladder)trans-76.9114.7178.2-168.2-100.6000111M420 F464 A492 W493 P499 V505 F508 F539M420-F490 PolarHBondContact O-N 2.88Å; F464-F490 HydrophobicContact CB-CD2 4.33Å; F490-A492 HydrophobicContact CE1-CB 4.17Å; F490-A492 HydrophobicContact CZ-CB 3.96Å; F490-W493 HydrophobicContact CD1-CB 3.86Å; F490-W493 HydrophobicContact CD1-CE3 4.17Å; F490-W493 HydrophobicContact CE1-CB 3.88Å; F490-W493 AromaticContact CE1-CE3 3.98Å; F490-W493 HydrophobicContact CE1-CE3 3.98Å; F490-P499 HydrophobicContact CE1-CG 4.2Å; F490-V505 HydrophobicContact CE1-CG2 4.06Å; F490-V505 HydrophobicContact CE2-CG2 4.23Å; F490-V505 HydrophobicContact CZ-CG2 3.62Å; F490-F508 HydrophobicContact CB-CE1 4.22Å; F490-F508 HydrophobicContact CB-CE2 4.09Å; F490-F508 HydrophobicContact CB-CZ 3.85Å; F490-F508 HydrophobicContact CD2-CB 4.11Å; F490-F508 HydrophobicContact CD2-CD1 4.09Å; F490-F508 AromaticContact CD2-CD2 3.84Å; F490-F508 HydrophobicContact CD2-CD2 3.84Å; F490-F508 HydrophobicContact CD2-CE1 4.39Å; F490-F508 HydrophobicContact CD2-CE2 4.15Å; F490-F508 AromaticContact CD2-CG 3.75Å; F490-F508 HydrophobicContact CD2-CG 3.75Å; F490-F508 HydrophobicContact CD2-CZ 4.4Å; F490-F508 HydrophobicContact CE2-CB 4.18Å; F490-F508 HydrophobicContact CE2-CG 4.32Å; F490-F539 HydrophobicContact CB-CZ 4.1Å; F490-F539 HydrophobicContact CD1-CE2 4.28Å; F490-F539 AromaticContact CD1-CZ 3.72Å; F490-F539 HydrophobicContact CD1-CZ 3.72Å; F490-F539 HydrophobicContact CD2-CZ 4.16Å; F490-F539 HydrophobicContact CE1-CZ 4.13Å; F490-F539 AromaticContact CG-CZ 3.72Å; F490-F539 HydrophobicContact CG-CZ 3.72Å
491L96.3Very high94.2Very high49 Ų4945 Ų4526%0.25726%0.261SS..  trans-101.8-23-171.3-63.1174.1000113.2K423 V460 D463 A465 H489 W493K423-L491 WeakPolarHBondContact CE-O 3.25Å; K423-L491 HydrophobicContact CG-CD2 4.46Å; V460-L491 HydrophobicContact CG1-CD1 4.4Å; D463-L491 WeakPolarHBondContact O-CA 3.17Å; D463-L491 PolarHBondContact O-N 3.48Å; A465-L491 HydrophobicContact CB-CD1 4.16Å; H489-L491 PolarHBondContact O-N 3.01Å; L491-W493 VanDerWaalsContact C-N 3.27Å; L491-W493 PolarHBondContact O-N 2.93Å
492A95.1Very high94.2Very high34 Ų3442.4 Ų42.428%0.28125%0.251SS..  trans-78.3-0.3-177.600000114.9D463 F490 P494D463-A492 HydrophobicContact CB-CB 4.18Å; D463-A492 PolarHBondContact O-N 3.41Å; F490-A492 HydrophobicContact CE1-CB 4.17Å; F490-A492 HydrophobicContact CZ-CB 3.96Å; A492-P494 WeakPolarHBondContact O-CD 3.4Å
493W95.1Very high94.2Very high5 Ų539.2 Ų39.22%0.01923%0.229CC..  trans-71.8123.1174.2-156.1-64.2000110.4F490 L491 G497 V498 P499 V505 R535 T538 F539 F583F490-W493 HydrophobicContact CD1-CB 3.86Å; F490-W493 HydrophobicContact CD1-CE3 4.17Å; F490-W493 HydrophobicContact CE1-CB 3.88Å; F490-W493 AromaticContact CE1-CE3 3.98Å; F490-W493 HydrophobicContact CE1-CE3 3.98Å; L491-W493 VanDerWaalsContact C-N 3.27Å; L491-W493 PolarHBondContact O-N 2.93Å; W493-G497 PolarHBondContact NE1-O 3.27Å; W493-V498 HydrophobicContact CZ2-CG1 4.31Å; W493-P499 HydrophobicContact CD2-CG 3.99Å; W493-P499 HydrophobicContact CE3-CG 3.91Å; W493-P499 HydrophobicContact CG-CG 4.36Å; W493-P499 HydrophobicContact CZ3-CG 4.35Å; W493-V505 HydrophobicContact CZ3-CG2 4.39Å; W493-R535 HydrophobicContact CD2-CB 4.35Å; W493-R535 HydrophobicContact CD2-CG 3.96Å; W493-R535 HydrophobicContact CE3-CB 4.48Å; W493-R535 HydrophobicContact CG-CG 4.34Å; W493-R535 HydrophobicContact CH2-CB 4.25Å; W493-R535 HydrophobicContact CH2-CG 4.4Å; W493-R535 HydrophobicContact CZ2-CB 4.15Å; W493-R535 HydrophobicContact CZ2-CG 3.8Å; W493-R535 HydrophobicContact CZ3-CB 4.43Å; W493-T538 HydrophobicContact CH2-CG2 3.77Å; W493-F539 HydrophobicContact CE3-CD2 4.29Å; W493-F539 AromaticContact CE3-CE2 3.39Å; W493-F539 HydrophobicContact CE3-CE2 3.39Å; W493-F539 AromaticContact CE3-CZ 3.97Å; W493-F539 HydrophobicContact CE3-CZ 3.97Å; W493-F539 HydrophobicContact CH2-CE2 4.42Å; W493-F539 AromaticContact CZ3-CD2 3.76Å; W493-F539 HydrophobicContact CZ3-CD2 3.76Å; W493-F539 AromaticContact CZ3-CE2 3.25Å; W493-F539 HydrophobicContact CZ3-CE2 3.25Å; W493-F539 AromaticContact CZ3-CZ 3.94Å; W493-F539 HydrophobicContact CZ3-CZ 3.94Å; W493-F583 HydrophobicContact CH2-CD1 4.48Å; W493-F583 HydrophobicContact CH2-CE1 4.47Å
494P91.7Very high94.1Very high44 Ų4438.2 Ų38.229%0.28623%0.226SC..  trans-73.1159.1-176.928.8-35.2000113.7A492 H496 V498 R535A492-P494 WeakPolarHBondContact O-CD 3.4Å; P494-H496 WeakPolarHBondContact CB-O 3.04Å; P494-H496 VanDerWaalsContact CG-O 3.29Å; P494-H496 WeakPolarHBondContact CG-O 3.15Å; P494-H496 PolarHBondContact O-N 2.88Å; P494-V498 WeakPolarHBondContact CG-O 3.27Å; P494-R535 PolarHBondContact O-NH2 2.82Å
495D77.6Confident94.1Very high65 Ų6533.6 Ų33.635%0.34821%0.206SC..SBendtrans-61.4-28.9176.5-73.64.6000113.2R427R427-D495 VanDerWaalsContact CG-OD2 3.27Å; R427-D495 WeakPolarHBondContact CG-OD2 3.39Å; R427-D495 IonicContact NE-OD2 2.92Å
496H79.5Confident94.1Very high130 Ų13033.7 Ų33.760%0.60221%0.206SC*.SBendtrans-126.1143.9175-78.6-23.3000111.2R427 P494R427-H496 PolarHBondContact NH1-CE1 3.25Å; R427-H496 PolarHBondContact NH1-NE2 2.66Å; R427-H496 PolarHBondContact NH2-CD2 2.71Å; R427-H496 PolarHBondContact NH2-CE1 3.39Å; R427-H496 VanDerWaalsContact NH2-CG 3.35Å; R427-H496 PolarHBondContact NH2-NE2 3.1Å; P494-H496 WeakPolarHBondContact CB-O 3.04Å; P494-H496 VanDerWaalsContact CG-O 3.29Å; P494-H496 WeakPolarHBondContact CG-O 3.15Å; P494-H496 PolarHBondContact O-N 2.88Å
497G90.2Very high93.9Very high44 Ų4435.4 Ų35.445%0.45422%0.219SC..SBendtrans68.1-134.2176.600000112.7W493W493-G497 PolarHBondContact NE1-O 3.27Å
498V95.6Very high93.9Very high37 Ų3735.4 Ų35.422%0.22422%0.219CC..  trans-136158.4-168.3-63.30000109.9W493 P494 A500 A579 Q580 F583W493-V498 HydrophobicContact CZ2-CG1 4.31Å; P494-V498 WeakPolarHBondContact CG-O 3.27Å; V498-A500 PolarHBondContact O-N 3.43Å; V498-A579 HydrophobicContact CG1-CB 4.42Å; V498-A579 WeakPolarHBondContact CG1-O 3.45Å; V498-Q580 HydrophobicContact CG1-CB 4.47Å; V498-Q580 HydrophobicContact CG1-CG 3.96Å; V498-F583 HydrophobicContact CB-CB 3.88Å; V498-F583 HydrophobicContact CB-CD1 4.4Å; V498-F583 HydrophobicContact CB-CD2 3.75Å; V498-F583 HydrophobicContact CB-CE2 4.41Å; V498-F583 HydrophobicContact CB-CG 3.74Å; V498-F583 HydrophobicContact CG1-CB 3.75Å; V498-F583 HydrophobicContact CG1-CG 4.07Å; V498-F583 HydrophobicContact CG2-CB 3.97Å; V498-F583 HydrophobicContact CG2-CD2 3.71Å; V498-F583 HydrophobicContact CG2-CG 4.04Å
499P95.7Very high93.8Very high7 Ų735.6 Ų35.65%0.04522%0.22CC..  trans-52.4136.9174.9-25.834.9000112F490 W493 V505 F583F490-P499 HydrophobicContact CE1-CG 4.2Å; W493-P499 HydrophobicContact CD2-CG 3.99Å; W493-P499 HydrophobicContact CE3-CG 3.91Å; W493-P499 HydrophobicContact CG-CG 4.36Å; W493-P499 HydrophobicContact CZ3-CG 4.35Å; P499-V505 HydrophobicContact CG-CG2 3.96Å; P499-F583 HydrophobicContact CB-CE2 4.08Å; P499-F583 HydrophobicContact CB-CZ 3.88Å; P499-F583 HydrophobicContact CG-CE1 4.36Å; P499-F583 HydrophobicContact CG-CE2 4.4Å; P499-F583 HydrophobicContact CG-CZ 3.88Å; P499-F583 WeakPolarHBondContact O-CE2 3.24Å
500A91.7Very high93.7Very high106 Ų10637.1 Ų37.188%0.87623%0.228SC*.SBendtrans-68.8-36-179.100000112.5V498V498-A500 PolarHBondContact O-N 3.43Å
501N93.6Very high93.6Very high93 Ų9339.7 Ų39.750%0.49724%0.24SC..  trans-103.2115.1174.9-178.96.8000109.7G503 S504N501-G503 PolarHBondContact O-N 2.84Å; N501-G503 PolarHBondContact OD1-N 3.41Å; N501-S504 PolarHBondContact O-N 3.14Å; N501-S504 PolarHBondContact O-OG 2.7Å
502P95.6Very high93.6Very high13 Ų1337.4 Ų37.48%0.08423%0.228CC..Hα-helixtrans-62.7-25.1175.2-19.931.4000113.8S504 V505 V506 F583 M586 A587P502-S504 VanDerWaalsContact C-N 3.26Å; P502-S504 PolarHBondContact O-N 2.81Å; P502-V505 PolarHBondContact O-N 2.68Å; P502-V506 PolarHBondContact O-N 2.85Å; P502-V506 VanDerWaalsContact O-N 3.14Å; P502-F583 HydrophobicContact CB-CE2 4.15Å; P502-F583 HydrophobicContact CB-CZ 4.37Å; P502-F583 HydrophobicContact CG-CE2 4.16Å; P502-M586 HydrophobicContact CG-CB 3.91Å; P502-M586 HydrophobicContact CG-CE 4.3Å; P502-A587 HydrophobicContact CB-CB 4.2Å
503G95.4Very high93.6Very high1 Ų136.1 Ų36.11%0.0122%0.216CC..Hα-helixtrans-60.8-29.6-179.300000114.2N501 V505 V506 N507N501-G503 PolarHBondContact O-N 2.84Å; N501-G503 PolarHBondContact OD1-N 3.41Å; G503-V505 VanDerWaalsContact C-N 3.34Å; G503-V505 PolarHBondContact O-N 3.38Å; G503-V506 PolarHBondContact O-N 3.41Å; G503-N507 VanDerWaalsContact O-CB 3.3Å; G503-N507 WeakPolarHBondContact O-CB 3.41Å; G503-N507 PolarHBondContact O-N 3.24Å; G503-N507 PolarHBondContact O-ND2 3.27Å
504S95.7Very high93.6Very high8 Ų840.4 Ų40.46%0.05624%0.236CC..Hα-helixtrans-64.9-38.5177.360.50000112.1N501 P502 F508N501-S504 PolarHBondContact O-N 3.14Å; N501-S504 PolarHBondContact O-OG 2.7Å; P502-S504 VanDerWaalsContact C-N 3.26Å; P502-S504 PolarHBondContact O-N 2.81Å; S504-F508 WeakPolarHBondContact O-CB 3.32Å; S504-F508 PolarHBondContact O-N 2.82Å
505V97.5Very high93.8Very high0 Ų039.6 Ų39.60%023%0.229CC..Hα-helixtrans-73.5-42.7176.1170.90000111.3F490 W493 P499 P502 G503 F508 L509 F539 I542 F583F490-V505 HydrophobicContact CE1-CG2 4.06Å; F490-V505 HydrophobicContact CE2-CG2 4.23Å; F490-V505 HydrophobicContact CZ-CG2 3.62Å; W493-V505 HydrophobicContact CZ3-CG2 4.39Å; P499-V505 HydrophobicContact CG-CG2 3.96Å; P502-V505 PolarHBondContact O-N 2.68Å; G503-V505 VanDerWaalsContact C-N 3.34Å; G503-V505 PolarHBondContact O-N 3.38Å; V505-F508 PolarHBondContact O-N 3.1Å; V505-L509 HydrophobicContact CG1-CD1 4.1Å; V505-L509 WeakPolarHBondContact O-CG 3.47Å; V505-L509 PolarHBondContact O-N 3.48Å; V505-F539 HydrophobicContact CB-CE1 4.5Å; V505-F539 HydrophobicContact CG1-CD1 4.11Å; V505-F539 HydrophobicContact CG1-CE1 3.75Å; V505-F539 HydrophobicContact CG1-CZ 4.29Å; V505-F539 HydrophobicContact CG2-CE1 4.37Å; V505-F539 HydrophobicContact CG2-CZ 4.16Å; V505-I542 HydrophobicContact CG1-CD1 3.92Å; V505-F583 HydrophobicContact CB-CE1 4.29Å; V505-F583 HydrophobicContact CB-CZ 4.3Å; V505-F583 HydrophobicContact CG1-CE1 4.46Å; V505-F583 HydrophobicContact CG2-CE1 3.91Å; V505-F583 HydrophobicContact CG2-CZ 3.89Å
506V97Very high94.6Very high4 Ų437.4 Ų37.42%0.02422%0.217CC..Hα-helixtrans-63-48.6179.7173.30000111P502 G503 F508 L509 E510 L546 A587 Y590 Y591P502-V506 PolarHBondContact O-N 2.85Å; P502-V506 VanDerWaalsContact O-N 3.14Å; G503-V506 PolarHBondContact O-N 3.41Å; V506-F508 VanDerWaalsContact C-N 3.31Å; V506-F508 PolarHBondContact O-N 2.8Å; V506-L509 PolarHBondContact O-N 3.3Å; V506-E510 WeakPolarHBondContact O-CG 3.46Å; V506-E510 PolarHBondContact O-N 2.83Å; V506-L546 HydrophobicContact CG1-CD1 4.28Å; V506-A587 HydrophobicContact CG2-CB 4.18Å; V506-A587 WeakPolarHBondContact CG2-O 3.41Å; V506-Y590 HydrophobicContact CB-CD1 4.07Å; V506-Y590 HydrophobicContact CB-CE1 4.32Å; V506-Y590 HydrophobicContact CG1-CD1 4.19Å; V506-Y590 HydrophobicContact CG1-CE1 4.36Å; V506-Y590 HydrophobicContact CG2-CD1 3.98Å; V506-Y591 HydrophobicContact CG1-CD2 3.77Å; V506-Y591 HydrophobicContact CG1-CG 4.41Å
507N95.2Very high95.2Very high91 Ų9136.8 Ų36.849%0.48722%0.222SC..Hα-helixtrans-62.8-38.9178.8-66.7-19.1000112G503 E510 E511G503-N507 VanDerWaalsContact O-CB 3.3Å; G503-N507 WeakPolarHBondContact O-CB 3.41Å; G503-N507 PolarHBondContact O-N 3.24Å; G503-N507 PolarHBondContact O-ND2 3.27Å; N507-E510 PolarHBondContact O-N 3.39Å; N507-E511 PolarHBondContact O-N 2.82Å; N507-E511 VanDerWaalsContact O-N 3.08Å
508F97.7Very high95.3Very high0 Ų041.1 Ų41.10%024%0.235CC..Hα-helixtrans-61.5-44.7175.1174.2-97.9000112.3V419 F464 Y488 F490 S504 V505 V506 E511 I512 F539V419-F508 HydrophobicContact CG1-CE1 3.68Å; V419-F508 HydrophobicContact CG1-CZ 3.91Å; F464-F508 HydrophobicContact CB-CD2 3.78Å; F464-F508 HydrophobicContact CB-CE2 3.76Å; F464-F508 HydrophobicContact CD1-CB 4.32Å; F464-F508 AromaticContact CD1-CD2 3.57Å; F464-F508 HydrophobicContact CD1-CD2 3.57Å; F464-F508 HydrophobicContact CD1-CE2 4.38Å; F464-F508 HydrophobicContact CD1-CG 4.41Å; F464-F508 AromaticContact CD2-CD2 3.9Å; F464-F508 HydrophobicContact CD2-CD2 3.9Å; F464-F508 HydrophobicContact CD2-CE2 4.11Å; F464-F508 HydrophobicContact CE1-CB 4.33Å; F464-F508 HydrophobicContact CE1-CD2 4.04Å; F464-F508 HydrophobicContact CE2-CD2 4.33Å; F464-F508 AromaticContact CG-CD2 3.49Å; F464-F508 HydrophobicContact CG-CD2 3.49Å; F464-F508 VanDerWaalsContact CG-CD2 3.49Å; F464-F508 AromaticContact CG-CE2 3.86Å; F464-F508 HydrophobicContact CG-CE2 3.86Å; F464-F508 HydrophobicContact CZ-CD2 4.39Å; Y488-F508 HydrophobicContact CD1-CD2 4.36Å; Y488-F508 AromaticContact CD1-CE2 3.85Å; Y488-F508 HydrophobicContact CD1-CE2 3.85Å; Y488-F508 HydrophobicContact CD1-CZ 4.41Å; Y488-F508 HydrophobicContact CG-CE2 4.29Å; Y488-F508 HydrophobicContact CG-CZ 4.47Å; F490-F508 HydrophobicContact CB-CE1 4.22Å; F490-F508 HydrophobicContact CB-CE2 4.09Å; F490-F508 HydrophobicContact CB-CZ 3.85Å; F490-F508 HydrophobicContact CD2-CB 4.11Å; F490-F508 HydrophobicContact CD2-CD1 4.09Å; F490-F508 AromaticContact CD2-CD2 3.84Å; F490-F508 HydrophobicContact CD2-CD2 3.84Å; F490-F508 HydrophobicContact CD2-CE1 4.39Å; F490-F508 HydrophobicContact CD2-CE2 4.15Å; F490-F508 AromaticContact CD2-CG 3.75Å; F490-F508 HydrophobicContact CD2-CG 3.75Å; F490-F508 HydrophobicContact CD2-CZ 4.4Å; F490-F508 HydrophobicContact CE2-CB 4.18Å; F490-F508 HydrophobicContact CE2-CG 4.32Å; S504-F508 WeakPolarHBondContact O-CB 3.32Å; S504-F508 PolarHBondContact O-N 2.82Å; V505-F508 PolarHBondContact O-N 3.1Å; V506-F508 VanDerWaalsContact C-N 3.31Å; V506-F508 PolarHBondContact O-N 2.8Å; F508-E511 PolarHBondContact O-N 3.43Å; F508-I512 HydrophobicContact CD1-CD1 3.72Å; F508-I512 HydrophobicContact CE1-CD1 3.36Å; F508-I512 HydrophobicContact CE2-CD1 4.27Å; F508-I512 HydrophobicContact CG-CD1 4.35Å; F508-I512 HydrophobicContact CZ-CD1 3.69Å; F508-I512 WeakPolarHBondContact O-CG1 3.41Å; F508-I512 PolarHBondContact O-N 2.85Å; F508-F539 HydrophobicContact CD1-CD1 4.24Å; F508-F539 AromaticContact CD1-CE1 3.49Å; F508-F539 HydrophobicContact CD1-CE1 3.49Å; F508-F539 VanDerWaalsContact CD1-CE1 3.49Å; F508-F539 HydrophobicContact CD1-CZ 4.3Å; F508-F539 HydrophobicContact CE1-CD1 4.2Å; F508-F539 AromaticContact CE1-CE1 3.61Å; F508-F539 HydrophobicContact CE1-CE1 3.61Å; F508-F539 HydrophobicContact CE1-CZ 4.25Å
509L97.7Very high95.2Very high7 Ų740.7 Ų40.74%0.03723%0.232CC..Hα-helixtrans-67.9-37.3176.2-74.8174.3000112.4V505 V506 E511 I512 N513 F539 I542 D543 L546V505-L509 HydrophobicContact CG1-CD1 4.1Å; V505-L509 WeakPolarHBondContact O-CG 3.47Å; V505-L509 PolarHBondContact O-N 3.48Å; V506-L509 PolarHBondContact O-N 3.3Å; L509-E511 VanDerWaalsContact C-N 3.35Å; L509-E511 PolarHBondContact O-N 3.04Å; L509-I512 PolarHBondContact O-N 2.86Å; L509-N513 WeakPolarHBondContact O-CB 3.26Å; L509-N513 PolarHBondContact O-N 3.43Å; L509-N513 PolarHBondContact O-ND2 2.99Å; L509-F539 HydrophobicContact CD1-CD1 4.28Å; L509-F539 HydrophobicContact CD2-CD1 3.91Å; L509-F539 HydrophobicContact CG-CD1 4.1Å; L509-I542 HydrophobicContact CD1-CB 3.97Å; L509-I542 HydrophobicContact CD1-CG2 3.55Å; L509-D543 HydrophobicContact CD1-CB 4.14Å; L509-D543 HydrophobicContact CD2-CB 4Å; L509-L546 HydrophobicContact CD1-CD1 4.49Å
510E94.9Very high94.8Very high41 Ų4146.1 Ų46.119%0.19227%0.267CS..Hα-helixtrans-59.9-42.8173.8-74.8-5912600112.1V506 N507 I512 N513 Q514 R550 Y591V506-E510 WeakPolarHBondContact O-CG 3.46Å; V506-E510 PolarHBondContact O-N 2.83Å; N507-E510 PolarHBondContact O-N 3.39Å; E510-I512 PolarHBondContact O-N 3.23Å; E510-N513 PolarHBondContact O-N 3.14Å; E510-Q514 WeakPolarHBondContact O-CB 3.48Å; E510-Q514 VanDerWaalsContact O-CG 3.27Å; E510-Q514 WeakPolarHBondContact O-CG 3.45Å; E510-Q514 PolarHBondContact O-N 3.44Å; E510-R550 IonicContact OE1-CZ 3.38Å; E510-R550 IonicContact OE1-NE 2.97Å; E510-R550 IonicContact OE1-NH2 2.84Å; E510-R550 PolarHBondContact OE1-NH2 3.25Å; E510-R550 IonicContact OE2-NH2 3.42Å; E510-Y591 WeakPolarHBondContact OE1-CE2 3.48Å
511E96.5Very high94.6Very high54 Ų5445.9 Ų45.925%0.25225%0.251SS..Hα-helixtrans-62.8-41.9177.5-170.9173.4129.700111.9R459 F464 Y488 N507 F508 L509 Q514 L515R459-E511 IonicContact CZ-OE1 3.34Å; R459-E511 IonicContact NE-OE1 3.87Å; R459-E511 IonicContact NH2-OE1 2.7Å; R459-E511 PolarHBondContact NH2-OE1 3.02Å; F464-E511 WeakPolarHBondContact CE2-OE1 3.43Å; F464-E511 VanDerWaalsContact CZ-OE2 3.3Å; F464-E511 WeakPolarHBondContact CZ-OE2 3.33Å; Y488-E511 HydrophobicContact CE1-CG 4.03Å; Y488-E511 WeakPolarHBondContact CE1-OE1 3.46Å; N507-E511 PolarHBondContact O-N 2.82Å; N507-E511 VanDerWaalsContact O-N 3.08Å; F508-E511 PolarHBondContact O-N 3.43Å; L509-E511 VanDerWaalsContact C-N 3.35Å; L509-E511 PolarHBondContact O-N 3.04Å; E511-Q514 PolarHBondContact O-N 3.02Å; E511-L515 PolarHBondContact O-N 3.32Å
512I97.6Very high94.3Very high2 Ų245.4 Ų45.41%0.0126%0.255CS..Hα-helixtrans-62.7-46.4175-71.4161.3000111I417 V419 Y488 F508 L509 E510 Q514 L515 E516 I525I417-I512 HydrophobicContact CD1-CG2 4.31Å; I417-I512 HydrophobicContact CG2-CG2 4.04Å; V419-I512 HydrophobicContact CG2-CD1 3.6Å; Y488-I512 HydrophobicContact CD1-CD1 4.17Å; Y488-I512 HydrophobicContact CD1-CG1 3.71Å; Y488-I512 HydrophobicContact CD2-CG1 4Å; Y488-I512 HydrophobicContact CE1-CG1 3.89Å; Y488-I512 HydrophobicContact CE2-CG1 4.17Å; Y488-I512 HydrophobicContact CG-CD1 4.1Å; Y488-I512 HydrophobicContact CG-CG1 3.78Å; F508-I512 HydrophobicContact CD1-CD1 3.72Å; F508-I512 HydrophobicContact CE1-CD1 3.36Å; F508-I512 HydrophobicContact CE2-CD1 4.27Å; F508-I512 HydrophobicContact CG-CD1 4.35Å; F508-I512 HydrophobicContact CZ-CD1 3.69Å; F508-I512 WeakPolarHBondContact O-CG1 3.41Å; F508-I512 PolarHBondContact O-N 2.85Å; L509-I512 PolarHBondContact O-N 2.86Å; E510-I512 PolarHBondContact O-N 3.23Å; I512-Q514 VanDerWaalsContact C-N 3.34Å; I512-Q514 PolarHBondContact O-N 3.49Å; I512-L515 WeakPolarHBondContact O-CB 3.4Å; I512-L515 PolarHBondContact O-N 3Å; I512-E516 PolarHBondContact O-N 3.46Å; I512-I525 HydrophobicContact CG2-CD1 4.22Å
513N95.1Very high94.3Very high7 Ų747.7 Ų47.74%0.03726%0.263CS..Hα-helixtrans-63.5-38.7-179.8-76.1-36.4000112.3R390 L509 E510 T517 D543 R550R390-N513 PolarHBondContact NH2-OD1 3.05Å; L509-N513 WeakPolarHBondContact O-CB 3.26Å; L509-N513 PolarHBondContact O-N 3.43Å; L509-N513 PolarHBondContact O-ND2 2.99Å; E510-N513 PolarHBondContact O-N 3.14Å; N513-T517 WeakPolarHBondContact O-CB 3.26Å; N513-T517 PolarHBondContact O-N 2.78Å; N513-T517 VanDerWaalsContact O-N 3.07Å; N513-T517 PolarHBondContact O-OG1 3.24Å; N513-D543 PolarHBondContact ND2-OD1 3.03Å; N513-D543 PolarHBondContact OD1-OD1 3.01Å; N513-R550 PolarHBondContact ND2-NH2 2.82Å
514Q94.9Very high94.4Very high94 Ų9448.3 Ų48.344%0.43927%0.267SS..Hα-helixtrans-65.5-43.8174-73.4172.42000111.7E510 E511 I512 T517 N518E510-Q514 WeakPolarHBondContact O-CB 3.48Å; E510-Q514 VanDerWaalsContact O-CG 3.27Å; E510-Q514 WeakPolarHBondContact O-CG 3.45Å; E510-Q514 PolarHBondContact O-N 3.44Å; E511-Q514 PolarHBondContact O-N 3.02Å; I512-Q514 VanDerWaalsContact C-N 3.34Å; I512-Q514 PolarHBondContact O-N 3.49Å; Q514-T517 PolarHBondContact O-N 2.61Å; Q514-N518 PolarHBondContact O-N 3.03Å; Q514-N518 PolarHBondContact O-ND2 3.48Å
515L96.1Very high94.5Very high27 Ų2748.1 Ų48.114%0.14127%0.266CS..Hα-helixtrans-59.4-49.8175.8170.865.4000111.1I417 Y486 Y488 E511 I512 T517 N518 L519I417-L515 HydrophobicContact CD1-CD2 4.02Å; I417-L515 HydrophobicContact CD1-CG 4.21Å; I417-L515 HydrophobicContact CG1-CD2 4.09Å; Y486-L515 HydrophobicContact CD1-CD1 4.5Å; Y486-L515 HydrophobicContact CD1-CD2 4.08Å; Y486-L515 HydrophobicContact CD2-CD1 4.13Å; Y486-L515 HydrophobicContact CD2-CD2 3.63Å; Y486-L515 HydrophobicContact CD2-CG 4.32Å; Y486-L515 HydrophobicContact CE1-CD1 4.3Å; Y486-L515 HydrophobicContact CE2-CD1 3.92Å; Y486-L515 HydrophobicContact CE2-CD2 4.28Å; Y486-L515 HydrophobicContact CG-CD1 4.4Å; Y486-L515 HydrophobicContact CG-CD2 3.5Å; Y486-L515 VanDerWaalsContact CG-CD2 3.5Å; Y488-L515 HydrophobicContact CE2-CD2 3.55Å; E511-L515 PolarHBondContact O-N 3.32Å; I512-L515 WeakPolarHBondContact O-CB 3.4Å; I512-L515 PolarHBondContact O-N 3Å; L515-T517 VanDerWaalsContact C-N 3.3Å; L515-T517 PolarHBondContact O-N 2.77Å; L515-N518 WeakPolarHBondContact O-CB 3.39Å; L515-N518 PolarHBondContact O-N 2.93Å; L515-L519 PolarHBondContact O-N 2.8Å
516E94.5Very high94.6Very high20 Ų2048.1 Ų48.19%0.09327%0.266CS..Hα-helixtrans-61.4-39.5-178.5-170.8-163.8171.500112.5R390 I417 I512 N518 L519 S522R390-E516 IonicContact CZ-OE1 2.84Å; R390-E516 IonicContact CZ-OE2 3.91Å; R390-E516 IonicContact NH1-OE1 3.73Å; R390-E516 PolarHBondContact NH1-OE1 3.12Å; R390-E516 IonicContact NH1-OE2 3.89Å; R390-E516 PolarHBondContact NH1-OE2 2.94Å; R390-E516 IonicContact NH2-OE2 2.87Å; R390-E516 PolarHBondContact NH2-OE2 2.78Å; I417-E516 HydrophobicContact CD1-CB 3.76Å; I417-E516 HydrophobicContact CD1-CG 4.27Å; I512-E516 PolarHBondContact O-N 3.46Å; E516-N518 PolarHBondContact O-N 3.46Å; E516-L519 WeakPolarHBondContact O-CB 3.31Å; E516-L519 PolarHBondContact O-N 2.78Å; E516-S522 PolarHBondContact OE1-OG 3.34Å
517T91.3Very high94.7Very high116 Ų11648.1 Ų48.171%0.71227%0.266SS*.Hα-helixtrans-60.1-27176.3-56.80000112.2N513 Q514 L515N513-T517 WeakPolarHBondContact O-CB 3.26Å; N513-T517 PolarHBondContact O-N 2.78Å; N513-T517 VanDerWaalsContact O-N 3.07Å; N513-T517 PolarHBondContact O-OG1 3.24Å; Q514-T517 PolarHBondContact O-N 2.61Å; L515-T517 VanDerWaalsContact C-N 3.3Å; L515-T517 PolarHBondContact O-N 2.77Å
518N93.2Very high94.9Very high135 Ų13543.8 Ų43.872%0.72224%0.243SC*.THydrogen-bonded Turntrans-89.2-4.6177-66.8-43.9000113.5Q514 L515 E516Q514-N518 PolarHBondContact O-N 3.03Å; Q514-N518 PolarHBondContact O-ND2 3.48Å; L515-N518 WeakPolarHBondContact O-CB 3.39Å; L515-N518 PolarHBondContact O-N 2.93Å; E516-N518 PolarHBondContact O-N 3.46Å
519L93.2Very high94.8Very high29 Ų2944.1 Ų44.115%0.15225%0.245CC..SBendtrans-83.4146.8173.9-65.4176.8000110.2R416 I417 Y486 L515 E516 D521R416-L519 HydrophobicContact CB-CD1 3.59Å; R416-L519 HydrophobicContact CG-CD1 4.16Å; I417-L519 HydrophobicContact CD1-CD1 4.13Å; I417-L519 HydrophobicContact CG1-CD1 4.19Å; Y486-L519 HydrophobicContact CE2-CD2 4.15Å; L515-L519 PolarHBondContact O-N 2.8Å; E516-L519 WeakPolarHBondContact O-CB 3.31Å; E516-L519 PolarHBondContact O-N 2.78Å; L519-D521 VanDerWaalsContact C-N 3.29Å; L519-D521 PolarHBondContact O-N 3.07Å
520P86.9Confident94.8Very high121 Ų12144.3 Ų44.379%0.78625%0.246SC*.SBendtrans-65.5-32.6-175.725.3-34.2000112.9
521D86.7Confident94.9Very high101 Ų10142.8 Ų42.854%0.5424%0.241SC..SBendtrans-130.3138.4-175-62.2-55.8000111.1L519 K523L519-D521 VanDerWaalsContact C-N 3.29Å; L519-D521 PolarHBondContact O-N 3.07Å; D521-K523 HydrophobicContact CB-CG 4.36Å; D521-K523 PolarHBondContact O-N 2.77Å
522S87.5Confident94.9Very high83 Ų8340.2 Ų40.258%0.5823%0.229SC*.  trans-79.8111.2169.6-171.60000108.9E516E516-S522 PolarHBondContact OE1-OG 3.34Å
523K95.7Very high94.9Very high60 Ų6040.4 Ų40.426%0.26123%0.23SC..  trans-119.8157.9176.4-61.6-66.4-173169.30109.3E414 D521 I525E414-K523 HydrophobicContact CB-CD 3.96Å; E414-K523 HydrophobicContact CB-CG 4.13Å; E414-K523 IonicContact OE1-NZ 3.96Å; E414-K523 PolarHBondContact OE1-NZ 3.49Å; E414-K523 IonicContact OE2-NZ 3.16Å; E414-K523 PolarHBondContact OE2-NZ 2.77Å; D521-K523 HydrophobicContact CB-CG 4.36Å; D521-K523 PolarHBondContact O-N 2.77Å; K523-I525 PolarHBondContact O-N 2.64Å
524P97.8Very high95Very high14 Ų1440.1 Ų40.19%0.09123%0.229CC..PPolyproline II helixtrans-58.8130.3-174.2-22.432.2000112.5L320 S391 I393 S415 I526L320-P524 HydrophobicContact CD1-CB 4.48Å; L320-P524 HydrophobicContact CD1-CG 4.26Å; S391-P524 WeakPolarHBondContact O-CA 3.4Å; I393-P524 HydrophobicContact CD1-CB 3.9Å; I393-P524 HydrophobicContact CD1-CG 4.41Å; I393-P524 HydrophobicContact CG1-CB 3.74Å; S415-P524 VanDerWaalsContact CB-O 3.28Å; S415-P524 WeakPolarHBondContact CB-O 3.14Å; S415-P524 PolarHBondContact OG-O 2.74Å; P524-I526 PolarHBondContact O-N 3.29Å
525I98.5Very high95.1Very high5 Ų537 Ų373%0.02621%0.213CC..EExtended strand (participates in β ladder)trans-78.9119.9172.2-59174.9000108.1S391 Y392 I393 I417 V419 I512 K523 V527S391-I525 PolarHBondContact O-N 3.22Å; S391-I525 VanDerWaalsContact O-N 3.08Å; Y392-I525 CarbonylContact C-O 3.52Å; Y392-I525 WeakPolarHBondContact CA-O 3.37Å; Y392-I525 WeakPolarHBondContact CB-O 3.26Å; Y392-I525 HydrophobicContact CD1-CB 3.99Å; Y392-I525 HydrophobicContact CE1-CD1 4.42Å; I393-I525 PolarHBondContact N-O 2.62Å; I417-I525 HydrophobicContact CB-CG1 4.43Å; I417-I525 HydrophobicContact CB-CG2 4.24Å; I417-I525 HydrophobicContact CG2-CG2 4.02Å; V419-I525 HydrophobicContact CG2-CG2 3.93Å; I512-I525 HydrophobicContact CG2-CD1 4.22Å; K523-I525 PolarHBondContact O-N 2.64Å; I525-V527 HydrophobicContact CG2-CG2 4Å; I525-V527 PolarHBondContact O-N 2.85Å
526I98.9Very high95.2Very high0 Ų035.8 Ų35.80%021%0.206CC..EExtended strand (participates in β ladder)trans-77.8123.7175.7-66.7163.5000107.9I393 T395 F406 M409 V410 S415 I417 I418 V419 P524I393-I526 HydrophobicContact CB-CG1 3.94Å; I393-I526 HydrophobicContact CD1-CG1 4.14Å; I393-I526 HydrophobicContact CG2-CG1 4.39Å; I393-I526 CarbonylContact O-C 3.51Å; I393-I526 WeakPolarHBondContact O-CA 3.31Å; T395-I526 HydrophobicContact CG2-CG2 3.93Å; F406-I526 HydrophobicContact CE2-CG2 4.06Å; F406-I526 HydrophobicContact CZ-CG2 4.27Å; M409-I526 HydrophobicContact CE-CD1 4.08Å; M409-I526 HydrophobicContact CE-CG1 4.38Å; M409-I526 HydrophobicContact CE-CG2 4.39Å; V410-I526 HydrophobicContact CB-CD1 4.21Å; V410-I526 HydrophobicContact CG2-CD1 3.46Å; V410-I526 VanDerWaalsContact CG2-CD1 3.46Å; S415-I526 VanDerWaalsContact CB-CD1 3.46Å; I417-I526 PolarHBondContact O-N 2.99Å; I418-I526 CarbonylContact C-O 3.43Å; I418-I526 WeakPolarHBondContact CA-O 3.45Å; I418-I526 HydrophobicContact CG1-CB 4.25Å; I418-I526 HydrophobicContact CG1-CD1 4.26Å; I418-I526 HydrophobicContact CG2-CB 4.44Å; I418-I526 HydrophobicContact CG2-CG2 4.21Å; V419-I526 PolarHBondContact N-O 3.28Å; P524-I526 PolarHBondContact O-N 3.29Å
527V98.9Very high95.4Very high4 Ų434.8 Ų34.82%0.02420%0.202CC..EExtended strand (participates in β ladder)trans-123.8126.5175.9-168.80000108.6Y392 I393 S394 T395 V419 I525 T536 F539 I540Y392-V527 HydrophobicContact CD1-CG2 4.14Å; I393-V527 PolarHBondContact O-N 2.86Å; S394-V527 WeakPolarHBondContact CA-O 3.47Å; T395-V527 PolarHBondContact N-O 2.83Å; V419-V527 HydrophobicContact CB-CB 4.36Å; V419-V527 HydrophobicContact CB-CG1 4.05Å; V419-V527 HydrophobicContact CB-CG2 4.16Å; V419-V527 HydrophobicContact CG1-CG1 4Å; V419-V527 HydrophobicContact CG2-CG2 4.46Å; V419-V527 CarbonylContact O-C 3.52Å; V419-V527 WeakPolarHBondContact O-CA 3.18Å; I525-V527 HydrophobicContact CG2-CG2 4Å; I525-V527 PolarHBondContact O-N 2.85Å; V527-T536 HydrophobicContact CB-CG2 3.94Å; V527-T536 HydrophobicContact CG1-CG2 3.79Å; V527-T536 VanDerWaalsContact O-CG2 3.27Å; V527-T536 WeakPolarHBondContact O-CG2 3.45Å; V527-F539 HydrophobicContact CG1-CB 4.28Å; V527-I540 HydrophobicContact CB-CD1 4.15Å; V527-I540 HydrophobicContact CB-CG1 4.19Å; V527-I540 HydrophobicContact CG1-CG1 4.36Å; V527-I540 HydrophobicContact CG2-CD1 4.25Å; V527-I540 HydrophobicContact CG2-CG1 3.99Å
528H98.8Very high95.8Very high0 Ų029.3 Ų29.30%017%0.168CC..EExtended strand (participates in β ladder)trans-143.3156.6178.779.994.6000112.2T395 V419 M420 A421 Y435 T536T395-H528 HydrophobicContact CG2-CB 3.63Å; T395-H528 WeakPolarHBondContact O-CA 3.37Å; T395-H528 WeakPolarHBondContact O-CB 3.28Å; V419-H528 PolarHBondContact O-N 3.43Å; M420-H528 WeakPolarHBondContact CB-NE2 3.39Å; M420-H528 VanDerWaalsContact CG-CE1 3.45Å; M420-H528 WeakPolarHBondContact CG-CE1 3.37Å; A421-H528 PolarHBondContact N-O 2.72Å; Y435-H528 AromaticContact CE1-CE1 3.77Å; Y435-H528 AromaticContact CE1-NE2 3.67Å; Y435-H528 AromaticContact CZ-NE2 3.63Å; Y435-H528 PolarHBondContact OH-NE2 3.03Å; H528-T536 VanDerWaalsContact C-OG1 3.25Å; H528-T536 WeakPolarHBondContact CA-OG1 3.38Å
529C97Very high96Very high7 Ų723 Ų235%0.04713%0.134CC..  trans-129.4-129.5168.366.30000107.7G397 A421 T422 G532 R535 T536G397-C529 WeakPolarHBondContact CA-O 3.44Å; G397-C529 PolarHBondContact N-O 3.49Å; G397-C529 VanDerWaalsContact N-O 3.11Å; A421-C529 HydrophobicContact CB-CB 4.17Å; T422-C529 VanDerWaalsContact CG2-C 3.44Å; C529-G532 PolarHBondContact SG-N 2.88Å; C529-R535 HydrophobicContact CB-CB 3.97Å; C529-T536 PolarHBondContact N-OG1 3.29Å; C529-T536 VanDerWaalsContact N-OG1 3.1Å; C529-T536 PolarHBondContact SG-OG1 2.88Å; C529-T536 VanDerWaalsContact SG-OG1 3.37Å
530S96.9Very high96.3Very high10 Ų1021.7 Ų21.77%0.0713%0.127CC..SBendtrans-84-59.6169.6-165.50000111.7R289 Y290 G397 K431R289-S530 VanDerWaalsContact CD-O 3.32Å; R289-S530 WeakPolarHBondContact CD-O 3.47Å; Y290-S530 PolarHBondContact OH-OG 2.89Å; G397-S530 PolarHBondContact N-O 3.23Å; K431-S530 WeakPolarHBondContact CA-OG 3.32Å; K431-S530 WeakPolarHBondContact O-CA 3.27Å; K431-S530 PolarHBondContact O-OG 3.08Å
531A96.7Very high96.8Very high9 Ų915.9 Ų15.97%0.0749%0.09CC..SBendtrans-86.2-18.1177.900000113.9Y290 I293 I533 R571Y290-A531 HydrophobicContact CD2-CB 3.85Å; Y290-A531 HydrophobicContact CE2-CB 3.61Å; I293-A531 HydrophobicContact CD1-CB 3.63Å; A531-I533 HydrophobicContact CB-CG1 3.93Å; A531-R571 PolarHBondContact O-NH2 3.14Å
532G97.8Very high97.4Very high0 Ų011.1 Ų11.10%06%0.064CC..SBendtrans73.330.2-176.200000114.3S394 T395 C529 T536 R571S394-G532 PolarHBondContact OG-O 2.98Å; T395-G532 WeakPolarHBondContact O-CA 3.49Å; C529-G532 PolarHBondContact SG-N 2.88Å; G532-T536 WeakPolarHBondContact CA-OG1 3.41Å; G532-R571 PolarHBondContact O-NE 3.4Å
533I97.4Very high97.9Very high7 Ų77.3 Ų7.34%0.0364%0.037CC..SBendtrans-137.9-46.8-178.658.6168.3000114.4I293 A531 G537 R571 S572 M574 V575 Q576I293-I533 HydrophobicContact CD1-CD1 3.91Å; I293-I533 HydrophobicContact CG1-CD1 4.32Å; I293-I533 HydrophobicContact CG2-CD1 3.92Å; I293-I533 HydrophobicContact CG2-CG1 4.38Å; I293-I533 HydrophobicContact CG2-CG2 4.1Å; A531-I533 HydrophobicContact CB-CG1 3.93Å; I533-G537 WeakPolarHBondContact O-CA 3.39Å; I533-G537 PolarHBondContact O-N 2.79Å; I533-R571 HydrophobicContact CG2-CG 4.07Å; I533-S572 WeakPolarHBondContact CG2-O 3.35Å; I533-M574 HydrophobicContact CB-SD 4.2Å; I533-M574 HydrophobicContact CG2-SD 4.17Å; I533-M574 WeakPolarHBondContact O-CA 3.49Å; I533-V575 PolarHBondContact O-N 3.41Å; I533-Q576 HydrophobicContact CD1-CG 4.01Å; I533-Q576 HydrophobicContact CG1-CG 4.02Å
534G96.4Very high97.9Very high1 Ų14.4 Ų4.41%0.013%0.025CC..Hα-helixtrans-70.9-80.4-178.400000113.7T536 G537 T538G534-T536 VanDerWaalsContact C-N 3.3Å; G534-T536 PolarHBondContact O-N 2.88Å; G534-G537 PolarHBondContact O-N 2.85Å; G534-T538 PolarHBondContact O-N 2.96Å; G534-T538 PolarHBondContact O-OG1 3.27Å
535R97.7Very high97.8Very high29 Ų293.8 Ų3.811%0.1092%0.021CC..Hα-helixtrans-58.1-43.8177.4-54.7-177.7-177.5156.72.8111.5A421 T422 E426 W493 P494 C529 G537 T538 F539A421-R535 HydrophobicContact CB-CB 4.07Å; A421-R535 WeakPolarHBondContact O-CD 3.31Å; A421-R535 PolarHBondContact O-NH1 2.81Å; T422-R535 PolarHBondContact OG1-NH1 3.35Å; E426-R535 IonicContact OE1-CZ 2.97Å; E426-R535 IonicContact OE1-NH1 3.46Å; E426-R535 PolarHBondContact OE1-NH1 3.49Å; E426-R535 IonicContact OE1-NH2 2.66Å; E426-R535 IonicContact OE2-CZ 3.92Å; E426-R535 IonicContact OE2-NH1 2.9Å; E426-R535 PolarHBondContact OE2-NH1 3.03Å; E426-R535 IonicContact OE2-NH2 3.93Å; E426-R535 PolarHBondContact OE2-NH2 3.23Å; W493-R535 HydrophobicContact CD2-CB 4.35Å; W493-R535 HydrophobicContact CD2-CG 3.96Å; W493-R535 HydrophobicContact CE3-CB 4.48Å; W493-R535 HydrophobicContact CG-CG 4.34Å; W493-R535 HydrophobicContact CH2-CB 4.25Å; W493-R535 HydrophobicContact CH2-CG 4.4Å; W493-R535 HydrophobicContact CZ2-CB 4.15Å; W493-R535 HydrophobicContact CZ2-CG 3.8Å; W493-R535 HydrophobicContact CZ3-CB 4.43Å; P494-R535 PolarHBondContact O-NH2 2.82Å; C529-R535 HydrophobicContact CB-CB 3.97Å; R535-G537 PolarHBondContact O-N 2.95Å; R535-T538 WeakPolarHBondContact O-CB 3.42Å; R535-T538 PolarHBondContact O-N 2.69Å; R535-T538 VanDerWaalsContact O-N 3.1Å; R535-F539 WeakPolarHBondContact O-CD2 3.46Å; R535-F539 PolarHBondContact O-N 2.84Å
536T98.5Very high97.5Very high0 Ų03.6 Ų3.60%02%0.02CC..Hα-helixtrans-53.6-52.4175.2-60.40000112.4S394 V527 H528 C529 G532 G534 T538 F539 I540 M574S394-T536 WeakPolarHBondContact OG-CG2 3.32Å; V527-T536 HydrophobicContact CB-CG2 3.94Å; V527-T536 HydrophobicContact CG1-CG2 3.79Å; V527-T536 VanDerWaalsContact O-CG2 3.27Å; V527-T536 WeakPolarHBondContact O-CG2 3.45Å; H528-T536 VanDerWaalsContact C-OG1 3.25Å; H528-T536 WeakPolarHBondContact CA-OG1 3.38Å; C529-T536 PolarHBondContact N-OG1 3.29Å; C529-T536 VanDerWaalsContact N-OG1 3.1Å; C529-T536 PolarHBondContact SG-OG1 2.88Å; C529-T536 VanDerWaalsContact SG-OG1 3.37Å; G532-T536 WeakPolarHBondContact CA-OG1 3.41Å; G534-T536 VanDerWaalsContact C-N 3.3Å; G534-T536 PolarHBondContact O-N 2.88Å; T536-T538 VanDerWaalsContact C-N 3.25Å; T536-T538 PolarHBondContact O-N 3.5Å; T536-F539 PolarHBondContact O-N 3.4Å; T536-I540 HydrophobicContact CG2-CD1 4.01Å; T536-I540 WeakPolarHBondContact O-CG1 3.47Å; T536-I540 PolarHBondContact O-N 3.03Å; T536-M574 HydrophobicContact CG2-CE 4.42Å
537G98.3Very high97.2Very high0 Ų04.2 Ų4.20%02%0.024CC..Hα-helixtrans-65.7-29.8177.800000113.5I533 G534 R535 A541I533-G537 WeakPolarHBondContact O-CA 3.39Å; I533-G537 PolarHBondContact O-N 2.79Å; G534-G537 PolarHBondContact O-N 2.85Å; R535-G537 PolarHBondContact O-N 2.95Å; G537-A541 WeakPolarHBondContact O-CB 3.28Å; G537-A541 PolarHBondContact O-N 2.89Å
538T98.4Very high96.7Very high0 Ų04 Ų40%02%0.023CC..Hα-helixtrans-65.7-46.9174.6-480000111.1W493 G534 R535 T536 A541 I542 F583 V584W493-T538 HydrophobicContact CH2-CG2 3.77Å; G534-T538 PolarHBondContact O-N 2.96Å; G534-T538 PolarHBondContact O-OG1 3.27Å; R535-T538 WeakPolarHBondContact O-CB 3.42Å; R535-T538 PolarHBondContact O-N 2.69Å; R535-T538 VanDerWaalsContact O-N 3.1Å; T536-T538 VanDerWaalsContact C-N 3.25Å; T536-T538 PolarHBondContact O-N 3.5Å; T538-A541 PolarHBondContact O-N 2.81Å; T538-I542 HydrophobicContact CG2-CD1 3.93Å; T538-I542 WeakPolarHBondContact O-CD1 3.11Å; T538-I542 WeakPolarHBondContact O-CG1 3.4Å; T538-I542 PolarHBondContact O-N 3.15Å; T538-F583 HydrophobicContact CG2-CD1 3.92Å; T538-V584 HydrophobicContact CG2-CG2 3.86Å
539F98.4Very high96.2Very high3 Ų34 Ų41%0.0132%0.023CC..Hα-helixtrans-60.7-48.6175.5-88.1-83.6000112.1A421 F490 W493 V505 F508 L509 V527 R535 T536 A541 I542 D543A421-F539 HydrophobicContact CB-CD2 3.86Å; A421-F539 HydrophobicContact CB-CE2 3.6Å; F490-F539 HydrophobicContact CB-CZ 4.1Å; F490-F539 HydrophobicContact CD1-CE2 4.28Å; F490-F539 AromaticContact CD1-CZ 3.72Å; F490-F539 HydrophobicContact CD1-CZ 3.72Å; F490-F539 HydrophobicContact CD2-CZ 4.16Å; F490-F539 HydrophobicContact CE1-CZ 4.13Å; F490-F539 AromaticContact CG-CZ 3.72Å; F490-F539 HydrophobicContact CG-CZ 3.72Å; W493-F539 HydrophobicContact CE3-CD2 4.29Å; W493-F539 AromaticContact CE3-CE2 3.39Å; W493-F539 HydrophobicContact CE3-CE2 3.39Å; W493-F539 AromaticContact CE3-CZ 3.97Å; W493-F539 HydrophobicContact CE3-CZ 3.97Å; W493-F539 HydrophobicContact CH2-CE2 4.42Å; W493-F539 AromaticContact CZ3-CD2 3.76Å; W493-F539 HydrophobicContact CZ3-CD2 3.76Å; W493-F539 AromaticContact CZ3-CE2 3.25Å; W493-F539 HydrophobicContact CZ3-CE2 3.25Å; W493-F539 AromaticContact CZ3-CZ 3.94Å; W493-F539 HydrophobicContact CZ3-CZ 3.94Å; V505-F539 HydrophobicContact CB-CE1 4.5Å; V505-F539 HydrophobicContact CG1-CD1 4.11Å; V505-F539 HydrophobicContact CG1-CE1 3.75Å; V505-F539 HydrophobicContact CG1-CZ 4.29Å; V505-F539 HydrophobicContact CG2-CE1 4.37Å; V505-F539 HydrophobicContact CG2-CZ 4.16Å; F508-F539 HydrophobicContact CD1-CD1 4.24Å; F508-F539 AromaticContact CD1-CE1 3.49Å; F508-F539 HydrophobicContact CD1-CE1 3.49Å; F508-F539 VanDerWaalsContact CD1-CE1 3.49Å; F508-F539 HydrophobicContact CD1-CZ 4.3Å; F508-F539 HydrophobicContact CE1-CD1 4.2Å; F508-F539 AromaticContact CE1-CE1 3.61Å; F508-F539 HydrophobicContact CE1-CE1 3.61Å; F508-F539 HydrophobicContact CE1-CZ 4.25Å; L509-F539 HydrophobicContact CD1-CD1 4.28Å; L509-F539 HydrophobicContact CD2-CD1 3.91Å; L509-F539 HydrophobicContact CG-CD1 4.1Å; V527-F539 HydrophobicContact CG1-CB 4.28Å; R535-F539 WeakPolarHBondContact O-CD2 3.46Å; R535-F539 PolarHBondContact O-N 2.84Å; T536-F539 PolarHBondContact O-N 3.4Å; F539-A541 PolarHBondContact O-N 2.73Å; F539-I542 PolarHBondContact O-N 2.94Å; F539-D543 WeakPolarHBondContact O-CB 3.47Å; F539-D543 PolarHBondContact O-N 3.02Å
540I98.6Very high95.7Very high1 Ų17.7 Ų7.71%0.0054%0.036CC..Hα-helixtrans-63.9-42.6-178.7-64.4176000110.8I321 Y392 V527 T536 D543 L544 L567 M574I321-I540 HydrophobicContact CD1-CD1 3.91Å; Y392-I540 HydrophobicContact CD1-CG1 4.13Å; Y392-I540 HydrophobicContact CD1-CG2 4.46Å; Y392-I540 HydrophobicContact CD2-CG2 3.84Å; Y392-I540 HydrophobicContact CE1-CG2 4.47Å; Y392-I540 HydrophobicContact CE2-CG2 3.83Å; Y392-I540 HydrophobicContact CG-CD1 4.23Å; Y392-I540 HydrophobicContact CG-CG1 4.25Å; Y392-I540 HydrophobicContact CG-CG2 4.15Å; V527-I540 HydrophobicContact CB-CD1 4.15Å; V527-I540 HydrophobicContact CB-CG1 4.19Å; V527-I540 HydrophobicContact CG1-CG1 4.36Å; V527-I540 HydrophobicContact CG2-CD1 4.25Å; V527-I540 HydrophobicContact CG2-CG1 3.99Å; T536-I540 HydrophobicContact CG2-CD1 4.01Å; T536-I540 WeakPolarHBondContact O-CG1 3.47Å; T536-I540 PolarHBondContact O-N 3.03Å; I540-D543 PolarHBondContact O-N 3.43Å; I540-L544 HydrophobicContact CG2-CD1 3.94Å; I540-L544 HydrophobicContact CG2-CG 4.34Å; I540-L544 WeakPolarHBondContact O-CB 3.2Å; I540-L544 WeakPolarHBondContact O-CG 3.37Å; I540-L544 PolarHBondContact O-N 2.92Å; I540-L567 HydrophobicContact CB-CD1 4.39Å; I540-L567 HydrophobicContact CG2-CD1 4.14Å; I540-L567 HydrophobicContact CG2-CD2 3.55Å; I540-M574 HydrophobicContact CD1-CE 3.92Å
541A98.2Very high95Very high0 Ų013.4 Ų13.40%06%0.059CC..Hα-helixtrans-61.6-45.6177.600000111.8G537 T538 F539 I545 T563 V564 L567 V584G537-A541 WeakPolarHBondContact O-CB 3.28Å; G537-A541 PolarHBondContact O-N 2.89Å; T538-A541 PolarHBondContact O-N 2.81Å; F539-A541 PolarHBondContact O-N 2.73Å; A541-I545 WeakPolarHBondContact O-CD1 3.3Å; A541-I545 VanDerWaalsContact O-CG1 3.26Å; A541-I545 WeakPolarHBondContact O-CG1 3.42Å; A541-I545 PolarHBondContact O-N 2.91Å; A541-T563 HydrophobicContact CB-CG2 4.06Å; A541-V564 HydrophobicContact CB-CG2 4.39Å; A541-L567 HydrophobicContact CB-CD1 3.78Å; A541-V584 HydrophobicContact CB-CG1 4.3Å; A541-V584 HydrophobicContact CB-CG2 4.24Å
542I98.4Very high94.1Very high0 Ų014.8 Ų14.80%07%0.065CC..Hα-helixtrans-61-54176.4-66.1164000109.3V505 L509 T538 F539 L544 I545 L546 F583 V584 A587V505-I542 HydrophobicContact CG1-CD1 3.92Å; L509-I542 HydrophobicContact CD1-CB 3.97Å; L509-I542 HydrophobicContact CD1-CG2 3.55Å; T538-I542 HydrophobicContact CG2-CD1 3.93Å; T538-I542 WeakPolarHBondContact O-CD1 3.11Å; T538-I542 WeakPolarHBondContact O-CG1 3.4Å; T538-I542 PolarHBondContact O-N 3.15Å; F539-I542 PolarHBondContact O-N 2.94Å; I542-L544 VanDerWaalsContact C-N 3.33Å; I542-L544 PolarHBondContact O-N 2.59Å; I542-I545 PolarHBondContact O-N 3.46Å; I542-L546 HydrophobicContact CG2-CD1 4.03Å; I542-L546 HydrophobicContact CG2-CD2 4.19Å; I542-L546 HydrophobicContact CG2-CG 3.9Å; I542-L546 VanDerWaalsContact O-CG 3.27Å; I542-L546 WeakPolarHBondContact O-CG 3.24Å; I542-L546 PolarHBondContact O-N 3.38Å; I542-F583 HydrophobicContact CD1-CD1 4.19Å; I542-F583 HydrophobicContact CD1-CE1 4.09Å; I542-V584 HydrophobicContact CG1-CB 4.33Å; I542-V584 HydrophobicContact CG1-CG1 4.03Å; I542-V584 HydrophobicContact CG1-CG2 4.27Å; I542-A587 HydrophobicContact CD1-CB 3.59Å; I542-A587 HydrophobicContact CG1-CB 3.97Å; I542-A587 HydrophobicContact CG2-CB 4.13Å
543D97.8Very high93.1Very high3 Ų315.8 Ų15.82%0.0168%0.076CC..Hα-helixtrans-56.5-45.6-176-166.150.3000112.5R390 Y392 L509 N513 F539 I540 I545 L546 C547R390-D543 IonicContact CZ-OD2 3.83Å; R390-D543 IonicContact NE-OD2 2.74Å; R390-D543 PolarHBondContact NE-OD2 3.47Å; R390-D543 IonicContact NH2-OD2 3.42Å; R390-D543 PolarHBondContact NH2-OD2 3.36Å; R390-D543 VanDerWaalsContact NH2-OD2 3.08Å; Y392-D543 PolarHBondContact OH-OD2 2.74Å; L509-D543 HydrophobicContact CD1-CB 4.14Å; L509-D543 HydrophobicContact CD2-CB 4Å; N513-D543 PolarHBondContact ND2-OD1 3.03Å; N513-D543 PolarHBondContact OD1-OD1 3.01Å; F539-D543 WeakPolarHBondContact O-CB 3.47Å; F539-D543 PolarHBondContact O-N 3.02Å; I540-D543 PolarHBondContact O-N 3.43Å; D543-I545 VanDerWaalsContact C-N 3.33Å; D543-I545 PolarHBondContact O-N 2.84Å; D543-L546 PolarHBondContact O-N 3.32Å; D543-C547 WeakPolarHBondContact O-CB 3.48Å; D543-C547 PolarHBondContact O-N 3.03Å; D543-C547 PolarHBondContact O-SG 3.5Å; D543-C547 VanDerWaalsContact O-SG 3.36Å
544L95.8Very high92.3Very high0 Ų016.6 Ų16.60%08%0.08CC..Hα-helixtrans-57.6-44.2176.1-79.7174.1000112.9V323 F385 R390 Y392 I540 I542 C547 L548 M566 L567V323-L544 HydrophobicContact CB-CD2 3.97Å; V323-L544 HydrophobicContact CG1-CD2 4.3Å; V323-L544 HydrophobicContact CG2-CD1 3.78Å; V323-L544 HydrophobicContact CG2-CD2 3.63Å; V323-L544 HydrophobicContact CG2-CG 4.37Å; F385-L544 HydrophobicContact CE1-CB 3.95Å; F385-L544 HydrophobicContact CE1-CD1 4.5Å; F385-L544 HydrophobicContact CZ-CD1 4.42Å; R390-L544 HydrophobicContact CB-CD2 4.15Å; Y392-L544 HydrophobicContact CE2-CD1 4.36Å; Y392-L544 HydrophobicContact CE2-CD2 3.74Å; Y392-L544 HydrophobicContact CE2-CG 3.89Å; I540-L544 HydrophobicContact CG2-CD1 3.94Å; I540-L544 HydrophobicContact CG2-CG 4.34Å; I540-L544 WeakPolarHBondContact O-CB 3.2Å; I540-L544 WeakPolarHBondContact O-CG 3.37Å; I540-L544 PolarHBondContact O-N 2.92Å; I542-L544 VanDerWaalsContact C-N 3.33Å; I542-L544 PolarHBondContact O-N 2.59Å; L544-C547 PolarHBondContact O-N 3.13Å; L544-L548 WeakPolarHBondContact O-CB 3.43Å; L544-L548 PolarHBondContact O-N 3.41Å; L544-M566 HydrophobicContact CD1-CE 3.58Å; L544-L567 HydrophobicContact CD1-CD2 3.97Å
545I95.4Very high91.1Very high1 Ų119.5 Ų19.51%0.0059%0.093CC..Hα-helixtrans-70.7-38.5179.2-63.4165.5000110.6A541 I542 D543 C547 L548 V549 I558 I560 T563 V584 V588A541-I545 WeakPolarHBondContact O-CD1 3.3Å; A541-I545 VanDerWaalsContact O-CG1 3.26Å; A541-I545 WeakPolarHBondContact O-CG1 3.42Å; A541-I545 PolarHBondContact O-N 2.91Å; I542-I545 PolarHBondContact O-N 3.46Å; D543-I545 VanDerWaalsContact C-N 3.33Å; D543-I545 PolarHBondContact O-N 2.84Å; I545-C547 VanDerWaalsContact C-N 3.35Å; I545-L548 WeakPolarHBondContact O-CB 3.45Å; I545-L548 PolarHBondContact O-N 3.27Å; I545-V549 HydrophobicContact CG2-CG2 4.43Å; I545-V549 WeakPolarHBondContact O-CG2 3.3Å; I545-V549 PolarHBondContact O-N 2.93Å; I545-I558 HydrophobicContact CG2-CB 4.3Å; I545-I558 HydrophobicContact CG2-CD1 4.36Å; I545-I558 HydrophobicContact CG2-CG2 4.03Å; I545-I560 HydrophobicContact CD1-CB 4.41Å; I545-I560 HydrophobicContact CD1-CG1 3.56Å; I545-T563 HydrophobicContact CD1-CG2 4.23Å; I545-T563 HydrophobicContact CG1-CG2 4.24Å; I545-V584 HydrophobicContact CD1-CG1 4.03Å; I545-V588 HydrophobicContact CB-CG2 3.99Å; I545-V588 HydrophobicContact CD1-CG2 4.03Å; I545-V588 HydrophobicContact CG2-CB 4.36Å; I545-V588 HydrophobicContact CG2-CG1 3.64Å; I545-V588 HydrophobicContact CG2-CG2 3.68Å
546L93.9Very high90.1Very high0 Ų018.5 Ų18.50%09%0.091CC..Hα-helixtrans-61.9-44.6174.7-58.5-160.5000110.8V506 L509 I542 D543 L548 V549 R550 Y591V506-L546 HydrophobicContact CG1-CD1 4.28Å; L509-L546 HydrophobicContact CD1-CD1 4.49Å; I542-L546 HydrophobicContact CG2-CD1 4.03Å; I542-L546 HydrophobicContact CG2-CD2 4.19Å; I542-L546 HydrophobicContact CG2-CG 3.9Å; I542-L546 VanDerWaalsContact O-CG 3.27Å; I542-L546 WeakPolarHBondContact O-CG 3.24Å; I542-L546 PolarHBondContact O-N 3.38Å; D543-L546 PolarHBondContact O-N 3.32Å; L546-L548 VanDerWaalsContact C-N 3.32Å; L546-L548 PolarHBondContact O-N 2.87Å; L546-V549 PolarHBondContact O-N 3.37Å; L546-R550 VanDerWaalsContact O-CB 3.25Å; L546-R550 WeakPolarHBondContact O-CB 3.36Å; L546-R550 PolarHBondContact O-N 3.03Å; L546-Y591 HydrophobicContact CB-CE1 4.48Å; L546-Y591 HydrophobicContact CD1-CD2 3.97Å; L546-Y591 HydrophobicContact CD1-CE2 4.39Å; L546-Y591 HydrophobicContact CD1-CG 4.2Å; L546-Y591 HydrophobicContact CD2-CD1 3.56Å; L546-Y591 HydrophobicContact CD2-CD2 4.07Å; L546-Y591 HydrophobicContact CD2-CE1 4.23Å; L546-Y591 HydrophobicContact CD2-CG 3.44Å; L546-Y591 VanDerWaalsContact CD2-CG 3.44Å; L546-Y591 HydrophobicContact CG-CD2 4.48Å; L546-Y591 HydrophobicContact CG-CG 4.3Å
547C91.8Very high89.4Confident13 Ų1321.4 Ų21.49%0.08811%0.109CC..Hα-helixtrans-59.4-41.7173.7-74.40000112.2V388 R390 D543 L544 I545 R550 K551V388-C547 HydrophobicContact CG1-CB 4.27Å; R390-C547 PolarHBondContact NE-SG 2.89Å; D543-C547 WeakPolarHBondContact O-CB 3.48Å; D543-C547 PolarHBondContact O-N 3.03Å; D543-C547 PolarHBondContact O-SG 3.5Å; D543-C547 VanDerWaalsContact O-SG 3.36Å; L544-C547 PolarHBondContact O-N 3.13Å; I545-C547 VanDerWaalsContact C-N 3.35Å; C547-R550 PolarHBondContact O-N 3.37Å; C547-K551 VanDerWaalsContact O-CB 3.24Å; C547-K551 WeakPolarHBondContact O-CB 3.47Å; C547-K551 PolarHBondContact O-N 2.54Å
548L88.7Confident89Confident1 Ų121.4 Ų21.41%0.00511%0.109CC..Hα-helixtrans-61.9-48.4176.4-179.362.3000111.8I384 V388 L544 I545 L546 K551 N552 I558I384-L548 VanDerWaalsContact O-CD1 3.25Å; I384-L548 WeakPolarHBondContact O-CD1 3.25Å; I384-L548 WeakPolarHBondContact O-CD2 3.21Å; V388-L548 HydrophobicContact CG2-CB 4.22Å; V388-L548 HydrophobicContact CG2-CD1 3.85Å; L544-L548 WeakPolarHBondContact O-CB 3.43Å; L544-L548 PolarHBondContact O-N 3.41Å; I545-L548 WeakPolarHBondContact O-CB 3.45Å; I545-L548 PolarHBondContact O-N 3.27Å; L546-L548 VanDerWaalsContact C-N 3.32Å; L546-L548 PolarHBondContact O-N 2.87Å; L548-K551 PolarHBondContact O-N 3.41Å; L548-N552 WeakPolarHBondContact CD1-ND2 3.48Å; L548-N552 WeakPolarHBondContact O-CB 3.26Å; L548-N552 PolarHBondContact O-N 3.29Å; L548-I558 HydrophobicContact CD2-CG2 4.04Å
549V88.2Confident88.7Confident0 Ų021.6 Ų21.60%011%0.11CC..Hα-helixtrans-66.9-39.9178175.70000111.4P238 I545 L546 K551 G553 L554 I558 Y591 I592 F595P238-V549 HydrophobicContact CG-CG2 4.27Å; I545-V549 HydrophobicContact CG2-CG2 4.43Å; I545-V549 WeakPolarHBondContact O-CG2 3.3Å; I545-V549 PolarHBondContact O-N 2.93Å; L546-V549 PolarHBondContact O-N 3.37Å; V549-K551 PolarHBondContact O-N 2.92Å; V549-G553 CarbonylContact O-C 3.58Å; V549-G553 WeakPolarHBondContact O-CA 3.13Å; V549-G553 PolarHBondContact O-N 3.32Å; V549-L554 HydrophobicContact CG1-CD2 4.1Å; V549-I558 HydrophobicContact CG2-CG2 3.89Å; V549-Y591 HydrophobicContact CB-CE1 4.12Å; V549-Y591 HydrophobicContact CG1-CD1 4.41Å; V549-Y591 HydrophobicContact CG1-CE1 3.9Å; V549-I592 HydrophobicContact CG1-CG1 4.43Å; V549-F595 HydrophobicContact CG1-CD1 4.29Å
550R85.7Confident88.6Confident83 Ų8321.4 Ų21.431%0.31311%0.109SC..Hα-helixtrans-64-41.7177.9-166.6-177.4-55.2107.21.6111.6E510 N513 L546 C547E510-R550 IonicContact OE1-CZ 3.38Å; E510-R550 IonicContact OE1-NE 2.97Å; E510-R550 IonicContact OE1-NH2 2.84Å; E510-R550 PolarHBondContact OE1-NH2 3.25Å; E510-R550 IonicContact OE2-NH2 3.42Å; N513-R550 PolarHBondContact ND2-NH2 2.82Å; L546-R550 VanDerWaalsContact O-CB 3.25Å; L546-R550 WeakPolarHBondContact O-CB 3.36Å; L546-R550 PolarHBondContact O-N 3.03Å; C547-R550 PolarHBondContact O-N 3.37Å
551K83.1Confident88.3Confident130 Ų13022.6 Ų22.657%0.56511%0.113SC*.Hα-helixtrans-75.2-46.9-178.4-176.2169-179.9141.70112.7G387 V388 C547 L548 V549G387-K551 WeakPolarHBondContact O-CD 3.46Å; G387-K551 WeakPolarHBondContact O-CE 3.35Å; G387-K551 PolarHBondContact O-NZ 3.24Å; V388-K551 HydrophobicContact CG2-CD 4.29Å; C547-K551 VanDerWaalsContact O-CB 3.24Å; C547-K551 WeakPolarHBondContact O-CB 3.47Å; C547-K551 PolarHBondContact O-N 2.54Å; L548-K551 PolarHBondContact O-N 3.41Å; V549-K551 PolarHBondContact O-N 2.92Å
552N78.2Confident88Confident38 Ų3823.3 Ų23.320%0.20312%0.117CC..Hα-helixtrans-100.8-3.4-171.3-65.4-25.5000113.3L4 N386 L548 C556L4-N552 HydrophobicContact CD1-CB 4.39Å; L4-N552 WeakPolarHBondContact CD2-O 3.33Å; N386-N552 PolarHBondContact O-ND2 3.23Å; N386-N552 VanDerWaalsContact O-ND2 3.12Å; L548-N552 WeakPolarHBondContact CD1-ND2 3.48Å; L548-N552 WeakPolarHBondContact O-CB 3.26Å; L548-N552 PolarHBondContact O-N 3.29Å; N552-C556 HydrophobicContact CB-CB 3.62Å
553G75.5Confident87.8Confident22 Ų2223.4 Ų23.423%0.22712%0.117CC..  trans74.7-177.3-178.400000113.5V549 Q555 C556V549-G553 CarbonylContact O-C 3.58Å; V549-G553 WeakPolarHBondContact O-CA 3.13Å; V549-G553 PolarHBondContact O-N 3.32Å; G553-Q555 PolarHBondContact O-N 3.37Å; G553-Q555 VanDerWaalsContact O-N 3.11Å; G553-C556 PolarHBondContact O-N 3.15Å; G553-C556 PolarHBondContact O-SG 3.06Å
554L81Confident87.7Confident24 Ų2423.2 Ų23.213%0.12612%0.116CC..THydrogen-bonded Turntrans-68.7-6.6-178.8-67.9172.4000114.7N237 P238 T239 V549 I592 F595 S596N237-L554 PolarHBondContact OD1-O 3.1Å; P238-L554 HydrophobicContact CB-CD2 4.1Å; T239-L554 HydrophobicContact CG2-CB 4.1Å; V549-L554 HydrophobicContact CG1-CD2 4.1Å; L554-I592 HydrophobicContact CD2-CB 4.46Å; L554-I592 HydrophobicContact CD2-CG1 4.43Å; L554-I592 HydrophobicContact CD2-CG2 3.75Å; L554-F595 HydrophobicContact CD1-CD1 4.21Å; L554-F595 HydrophobicContact CD2-CD1 3.81Å; L554-F595 HydrophobicContact CD2-CE1 4.48Å; L554-F595 HydrophobicContact CG-CD1 3.78Å; L554-F595 HydrophobicContact CG-CE1 4.08Å; L554-S596 WeakPolarHBondContact CD1-OG 3.43Å
555Q70.6Confident87.5Confident61 Ų6124.6 Ų24.629%0.28512%0.123SC..THydrogen-bonded Turntrans-95.9-1.8-178-50-54.2-11.500113.1L4 N107 G553L4-Q555 HydrophobicContact CD2-CB 4.02Å; N107-Q555 PolarHBondContact ND2-OE1 3.45Å; G553-Q555 PolarHBondContact O-N 3.37Å; G553-Q555 VanDerWaalsContact O-N 3.11Å
556C78.3Confident87.3Confident9 Ų924.6 Ų24.66%0.06112%0.123CC..SBendtrans-68.1169173.472.70000111.2P238 N552 G553P238-C556 WeakPolarHBondContact CD-O 3.12Å; N552-C556 HydrophobicContact CB-CB 3.62Å; G553-C556 PolarHBondContact O-N 3.15Å; G553-C556 PolarHBondContact O-SG 3.06Å
557T83.1Confident87.4Confident61 Ų6124.6 Ų24.637%0.37412%0.123SC..  trans-100.6132.2167-60.70000108K235K235-T557 HydrophobicContact CB-CG2 3.78Å; K235-T557 HydrophobicContact CD-CG2 4.24Å; K235-T557 HydrophobicContact CG-CG2 4.13Å
558I90.5Very high87.5Confident0 Ų024.5 Ų24.50%012%0.12CC..EExtended strand (participates in β ladder)trans-110.4148.3171.564172.9000109.2I236 P238 I241 I545 L548 V549 V588 I592I236-I558 HydrophobicContact CB-CD1 4.5Å; I236-I558 HydrophobicContact CB-CG1 3.93Å; I236-I558 HydrophobicContact CG2-CD1 4.45Å; I236-I558 HydrophobicContact CG2-CG1 4.32Å; I236-I558 PolarHBondContact N-O 2.79Å; I236-I558 WeakPolarHBondContact O-CG1 3.29Å; I236-I558 PolarHBondContact O-N 3.38Å; P238-I558 HydrophobicContact CG-CG1 4.48Å; P238-I558 HydrophobicContact CG-CG2 4.03Å; I241-I558 HydrophobicContact CD1-CD1 4.03Å; I545-I558 HydrophobicContact CG2-CB 4.3Å; I545-I558 HydrophobicContact CG2-CD1 4.36Å; I545-I558 HydrophobicContact CG2-CG2 4.03Å; L548-I558 HydrophobicContact CD2-CG2 4.04Å; V549-I558 HydrophobicContact CG2-CG2 3.89Å; I558-V588 HydrophobicContact CD1-CG1 3.75Å; I558-I592 HydrophobicContact CD1-CD1 4.14Å
559D92.4Very high87.7Confident3 Ų324.8 Ų24.82%0.01612%0.122CC..EExtended strand (participates in β ladder)trans-140.8105.3172-171.8-34.4000109.1T234 K235 I384 R561 Q562 T563T234-D559 WeakPolarHBondContact CB-OD1 3.42Å; T234-D559 PolarHBondContact OG1-OD1 3.34Å; T234-D559 PolarHBondContact OG1-OD2 3.43Å; K235-D559 HydrophobicContact CG-CB 4.29Å; K235-D559 PolarHBondContact N-OD2 3.41Å; I384-D559 HydrophobicContact CD1-CB 4.05Å; I384-D559 HydrophobicContact CG2-CB 4.31Å; D559-R561 WeakPolarHBondContact OD1-CA 3.44Å; D559-R561 WeakPolarHBondContact OD1-CB 3.36Å; D559-R561 PolarHBondContact OD1-N 3.06Å; D559-Q562 HydrophobicContact CB-CB 3.88Å; D559-Q562 VanDerWaalsContact CG-CB 3.46Å; D559-Q562 WeakPolarHBondContact OD1-CB 3.47Å; D559-Q562 PolarHBondContact OD1-N 2.84Å; D559-T563 WeakPolarHBondContact O-CB 3.41Å; D559-T563 PolarHBondContact O-N 3.35Å; D559-T563 PolarHBondContact O-OG1 2.83Å
560I95.4Very high87.9Confident0 Ų025.6 Ų25.60%013%0.126CC..Hα-helixtrans-69.7-37.8-177.8-70.7162.2000110.6I545 T563 V564 Y581 V584 Y585I545-I560 HydrophobicContact CD1-CB 4.41Å; I545-I560 HydrophobicContact CD1-CG1 3.56Å; I560-T563 PolarHBondContact O-N 2.98Å; I560-V564 WeakPolarHBondContact O-CG2 3.33Å; I560-V564 PolarHBondContact O-N 3.05Å; I560-Y581 HydrophobicContact CG2-CD2 4.42Å; I560-Y581 HydrophobicContact CG2-CE2 3.8Å; I560-V584 HydrophobicContact CD1-CG1 4.41Å; I560-V584 HydrophobicContact CG1-CG1 4.18Å; I560-V584 HydrophobicContact CG2-CB 4.12Å; I560-V584 HydrophobicContact CG2-CG1 3.75Å; I560-Y585 HydrophobicContact CB-CD2 4.28Å; I560-Y585 HydrophobicContact CB-CE2 3.79Å; I560-Y585 HydrophobicContact CD1-CD1 3.42Å; I560-Y585 VanDerWaalsContact CD1-CD1 3.42Å; I560-Y585 HydrophobicContact CD1-CD2 3.54Å; I560-Y585 HydrophobicContact CD1-CE1 3.61Å; I560-Y585 HydrophobicContact CD1-CE2 3.72Å; I560-Y585 HydrophobicContact CD1-CG 3.39Å; I560-Y585 HydrophobicContact CG1-CD2 4.47Å; I560-Y585 HydrophobicContact CG1-CE2 4.35Å; I560-Y585 HydrophobicContact CG2-CD2 3.89Å; I560-Y585 HydrophobicContact CG2-CE2 3.65Å
561R93.1Very high88.4Confident25 Ų2521.7 Ų21.79%0.09411%0.112CC..Hα-helixtrans-63.4-51.5178.5-168-169.354.774.99.3110T234 L265 D559 T563 V564 Q565 Y581T234-R561 HydrophobicContact CG2-CB 3.79Å; T234-R561 HydrophobicContact CG2-CG 4.23Å; T234-R561 VanDerWaalsContact CG2-NE 3.26Å; T234-R561 PolarHBondContact OG1-NE 3.21Å; T234-R561 VanDerWaalsContact OG1-NE 3.13Å; T234-R561 PolarHBondContact OG1-NH2 2.8Å; L265-R561 HydrophobicContact CD1-CG 3.9Å; L265-R561 HydrophobicContact CD2-CG 3.71Å; L265-R561 WeakPolarHBondContact CD2-O 3.43Å; L265-R561 HydrophobicContact CG-CG 3.65Å; D559-R561 WeakPolarHBondContact OD1-CA 3.44Å; D559-R561 WeakPolarHBondContact OD1-CB 3.36Å; D559-R561 PolarHBondContact OD1-N 3.06Å; R561-T563 VanDerWaalsContact C-N 3.32Å; R561-T563 PolarHBondContact O-N 2.85Å; R561-V564 PolarHBondContact O-N 3.37Å; R561-Q565 WeakPolarHBondContact O-CB 3.32Å; R561-Q565 PolarHBondContact O-N 3.32Å; R561-Y581 WeakPolarHBondContact CA-OH 3.27Å; R561-Y581 VanDerWaalsContact CB-OH 3.32Å; R561-Y581 WeakPolarHBondContact CB-OH 3.39Å; R561-Y581 PolarHBondContact N-OH 2.74Å
562Q90.4Very high88.9Confident16 Ų1616.5 Ų16.58%0.0759%0.092CC..Hα-helixtrans-64.3-36.7179.6-172.7171.815.400112.2P380 I384 D559 V564 Q565 M566P380-Q562 VanDerWaalsContact C-NE2 3.31Å; P380-Q562 PolarHBondContact O-NE2 2.85Å; I384-Q562 HydrophobicContact CD1-CB 4.1Å; I384-Q562 HydrophobicContact CD1-CG 4.13Å; D559-Q562 HydrophobicContact CB-CB 3.88Å; D559-Q562 VanDerWaalsContact CG-CB 3.46Å; D559-Q562 WeakPolarHBondContact OD1-CB 3.47Å; D559-Q562 PolarHBondContact OD1-N 2.84Å; Q562-V564 PolarHBondContact O-N 3.18Å; Q562-Q565 PolarHBondContact O-N 3.28Å; Q562-M566 WeakPolarHBondContact O-CB 3.29Å; Q562-M566 PolarHBondContact O-N 3Å
563T94.8Very high89.6Confident1 Ų115.3 Ų15.31%0.0069%0.089CC..Hα-helixtrans-56.4-50.2171.1-62.10000111.2F385 A541 I545 D559 I560 R561 M566 L567F385-T563 HydrophobicContact CZ-CG2 3.84Å; F385-T563 WeakPolarHBondContact CZ-OG1 3.43Å; A541-T563 HydrophobicContact CB-CG2 4.06Å; I545-T563 HydrophobicContact CD1-CG2 4.23Å; I545-T563 HydrophobicContact CG1-CG2 4.24Å; D559-T563 WeakPolarHBondContact O-CB 3.41Å; D559-T563 PolarHBondContact O-N 3.35Å; D559-T563 PolarHBondContact O-OG1 2.83Å; I560-T563 PolarHBondContact O-N 2.98Å; R561-T563 VanDerWaalsContact C-N 3.32Å; R561-T563 PolarHBondContact O-N 2.85Å; T563-M566 PolarHBondContact O-N 2.71Å; T563-L567 WeakPolarHBondContact O-CG 3.48Å; T563-L567 PolarHBondContact O-N 2.81Å
564V95.2Very high90.6Very high0 Ų014.3 Ų14.30%08%0.078CC..Hα-helixtrans-67.3-37.8179.4175.30000111.6L265 A541 I560 R561 Q562 L567 R568 M574 V575 Y581L265-V564 HydrophobicContact CD1-CB 4.06Å; L265-V564 HydrophobicContact CD1-CG1 3.89Å; A541-V564 HydrophobicContact CB-CG2 4.39Å; I560-V564 WeakPolarHBondContact O-CG2 3.33Å; I560-V564 PolarHBondContact O-N 3.05Å; R561-V564 PolarHBondContact O-N 3.37Å; Q562-V564 PolarHBondContact O-N 3.18Å; V564-L567 PolarHBondContact O-N 3.39Å; V564-R568 HydrophobicContact CG1-CG 4.39Å; V564-R568 WeakPolarHBondContact O-CB 3.37Å; V564-R568 WeakPolarHBondContact O-CG 3.47Å; V564-R568 PolarHBondContact O-N 3.44Å; V564-M574 WeakPolarHBondContact CG1-O 3.49Å; V564-V575 HydrophobicContact CG1-CB 4.03Å; V564-V575 HydrophobicContact CG1-CG2 4.24Å; V564-V575 HydrophobicContact CG2-CB 4.42Å; V564-V575 HydrophobicContact CG2-CG2 3.95Å; V564-Y581 HydrophobicContact CG2-CD2 4.22Å; V564-Y581 HydrophobicContact CG2-CE2 4.17Å
565Q92.3Very high91.3Very high29 Ų2913.1 Ų13.114%0.1367%0.072CC..Hα-helixtrans-59.1-46.9174.9-174.2179.3-12.400111.6L265 Q268 E381 R561 Q562 L567 R568 S569L265-Q565 HydrophobicContact CD2-CB 3.8Å; Q268-Q565 VanDerWaalsContact OE1-OE1 3.09Å; E381-Q565 HydrophobicContact CG-CG 4.41Å; E381-Q565 PolarHBondContact OE1-NE2 2.79Å; R561-Q565 WeakPolarHBondContact O-CB 3.32Å; R561-Q565 PolarHBondContact O-N 3.32Å; Q562-Q565 PolarHBondContact O-N 3.28Å; Q565-L567 VanDerWaalsContact C-N 3.35Å; Q565-L567 PolarHBondContact O-N 3.31Å; Q565-R568 CarbonylContact O-C 3.55Å; Q565-R568 WeakPolarHBondContact O-CA 3.42Å; Q565-R568 WeakPolarHBondContact O-CB 3.4Å; Q565-R568 PolarHBondContact O-N 3.28Å; Q565-R568 VanDerWaalsContact O-N 3.13Å; Q565-S569 PolarHBondContact O-N 3.23Å
566M92Very high92.5Very high0 Ų014.4 Ų14.40%08%0.078CC..Hα-helixtrans-60.7-42.3174.8174.8-76.3-62.800111.6V323 E381 F382 F385 L544 Q562 T563 R568 S569 Q570V323-M566 HydrophobicContact CG2-CE 3.61Å; V323-M566 HydrophobicContact CG2-SD 3.96Å; E381-M566 HydrophobicContact CB-CB 4.25Å; F382-M566 HydrophobicContact CD1-CG 4.25Å; F382-M566 HydrophobicContact CE1-CG 3.86Å; F382-M566 HydrophobicContact CE1-SD 4.34Å; F382-M566 HydrophobicContact CE2-CG 4.39Å; F382-M566 HydrophobicContact CZ-CG 3.95Å; F385-M566 HydrophobicContact CD2-CE 4.46Å; F385-M566 HydrophobicContact CE2-CE 3.61Å; F385-M566 HydrophobicContact CE2-CG 4.43Å; F385-M566 HydrophobicContact CZ-CE 3.85Å; L544-M566 HydrophobicContact CD1-CE 3.58Å; Q562-M566 WeakPolarHBondContact O-CB 3.29Å; Q562-M566 PolarHBondContact O-N 3Å; T563-M566 PolarHBondContact O-N 2.71Å; M566-R568 VanDerWaalsContact C-N 3.29Å; M566-R568 PolarHBondContact O-N 2.99Å; M566-S569 PolarHBondContact O-N 3.13Å; M566-S569 PolarHBondContact O-OG 2.9Å; M566-Q570 PolarHBondContact O-N 2.82Å; M566-Q570 PolarHBondContact SD-NE2 3.23Å
567L95.3Very high93.2Very high0 Ų016.9 Ų16.90%09%0.092CC..Hα-helixtrans-62.3-40.2174.5-66.5177000111.5I321 I540 A541 L544 T563 V564 Q565 S569 Q570 R571 M574I321-L567 HydrophobicContact CD1-CD2 4.34Å; I321-L567 HydrophobicContact CG2-CD2 3.62Å; I540-L567 HydrophobicContact CB-CD1 4.39Å; I540-L567 HydrophobicContact CG2-CD1 4.14Å; I540-L567 HydrophobicContact CG2-CD2 3.55Å; A541-L567 HydrophobicContact CB-CD1 3.78Å; L544-L567 HydrophobicContact CD1-CD2 3.97Å; T563-L567 WeakPolarHBondContact O-CG 3.48Å; T563-L567 PolarHBondContact O-N 2.81Å; V564-L567 PolarHBondContact O-N 3.39Å; Q565-L567 VanDerWaalsContact C-N 3.35Å; Q565-L567 PolarHBondContact O-N 3.31Å; L567-S569 VanDerWaalsContact C-N 3.28Å; L567-S569 PolarHBondContact O-N 2.75Å; L567-Q570 PolarHBondContact O-N 3.21Å; L567-R571 PolarHBondContact O-N 3.38Å; L567-M574 HydrophobicContact CB-CB 3.77Å; L567-M574 HydrophobicContact CB-CG 4.02Å
568R94Very high93.7Very high11 Ų1117.1 Ų17.14%0.0429%0.089CC..Hα-helixtrans-67.4-22.3177.7-75.5177174.9-149.7-4.3113.5L265 E269 F296 V564 Q565 M566 R571 M574 V575L265-R568 PolarHBondContact O-NH1 3.44Å; E269-R568 WeakPolarHBondContact OE1-CD 3.46Å; E269-R568 IonicContact OE1-CZ 3.79Å; E269-R568 IonicContact OE1-NE 3.98Å; E269-R568 PolarHBondContact OE1-NE 2.95Å; E269-R568 IonicContact OE1-NH1 3.79Å; E269-R568 PolarHBondContact OE1-NH1 3Å; E269-R568 IonicContact OE1-NH2 3.79Å; E269-R568 IonicContact OE2-NH1 2.76Å; F296-R568 VanDerWaalsContact CE2-O 3.27Å; F296-R568 WeakPolarHBondContact CE2-O 3.41Å; V564-R568 HydrophobicContact CG1-CG 4.39Å; V564-R568 WeakPolarHBondContact O-CB 3.37Å; V564-R568 WeakPolarHBondContact O-CG 3.47Å; V564-R568 PolarHBondContact O-N 3.44Å; Q565-R568 CarbonylContact O-C 3.55Å; Q565-R568 WeakPolarHBondContact O-CA 3.42Å; Q565-R568 WeakPolarHBondContact O-CB 3.4Å; Q565-R568 PolarHBondContact O-N 3.28Å; Q565-R568 VanDerWaalsContact O-N 3.13Å; M566-R568 VanDerWaalsContact C-N 3.29Å; M566-R568 PolarHBondContact O-N 2.99Å; R568-R571 VanDerWaalsContact CA-O 3.3Å; R568-R571 WeakPolarHBondContact CA-O 3.33Å; R568-M574 HydrophobicContact CG-CB 4.12Å; R568-M574 PolarHBondContact NE-O 3.48Å; R568-V575 PolarHBondContact NH2-O 2.95Å
569S92Very high93.9Very high7 Ų719.2 Ų19.25%0.04911%0.106CC..Hα-helixtrans-79.1-20.8173.372.20000113.3Y274 H298 Q565 M566 L567Y274-S569 WeakPolarHBondContact CE2-O 3.28Å; H298-S569 PolarHBondContact NE2-O 3.28Å; Q565-S569 PolarHBondContact O-N 3.23Å; M566-S569 PolarHBondContact O-N 3.13Å; M566-S569 PolarHBondContact O-OG 2.9Å; L567-S569 VanDerWaalsContact C-N 3.28Å; L567-S569 PolarHBondContact O-N 2.75Å
570Q94.2Very high94.1Very high18 Ų1819.9 Ų19.98%0.08411%0.11CC..Hα-helixtrans-99.1-28.5177.7-60.2-168.47000113.5F296 T299 I321 E322 M566 L567F296-Q570 WeakPolarHBondContact CD2-O 3.42Å; T299-Q570 HydrophobicContact CG2-CB 4.37Å; T299-Q570 PolarHBondContact OG1-O 3.08Å; I321-Q570 HydrophobicContact CG1-CB 4.17Å; E322-Q570 PolarHBondContact O-NE2 3.04Å; E322-Q570 PolarHBondContact O-OE1 2.82Å; M566-Q570 PolarHBondContact O-N 2.82Å; M566-Q570 PolarHBondContact SD-NE2 3.23Å; L567-Q570 PolarHBondContact O-N 3.21Å
571R95.6Very high94.2Very high1 Ų119.9 Ų19.90%0.00411%0.11CC..SBendtrans-148.4129.8169.5-175.4171.3177.583.3-2.3110.2N317 N319 S394 A531 G532 I533 L567 R568 M574N317-R571 PolarHBondContact OD1-NH1 3.33Å; N317-R571 PolarHBondContact OD1-NH2 2.97Å; N319-R571 HydrophobicContact CB-CB 4.07Å; N319-R571 HydrophobicContact CB-CG 4.36Å; N319-R571 WeakPolarHBondContact OD1-CG 3.38Å; N319-R571 PolarHBondContact OD1-NH1 2.84Å; S394-R571 VanDerWaalsContact OG-CD 3.24Å; S394-R571 WeakPolarHBondContact OG-CD 3.28Å; A531-R571 PolarHBondContact O-NH2 3.14Å; G532-R571 PolarHBondContact O-NE 3.4Å; I533-R571 HydrophobicContact CG2-CG 4.07Å; L567-R571 PolarHBondContact O-N 3.38Å; R568-R571 VanDerWaalsContact CA-O 3.3Å; R568-R571 WeakPolarHBondContact CA-O 3.33Å; R571-M574 HydrophobicContact CB-CG 4.09Å; R571-M574 HydrophobicContact CB-SD 4.21Å; R571-M574 HydrophobicContact CG-SD 4.27Å; R571-M574 WeakPolarHBondContact O-CG 3.45Å
572S92.7Very high94.3Very high21 Ų2121.2 Ų21.215%0.14712%0.116CC..THydrogen-bonded Turntrans-60.7142-17659.80000113.3F296 I533 M574F296-S572 VanDerWaalsContact CE2-N 3.34Å; F296-S572 VanDerWaalsContact CZ-CB 3.49Å; F296-S572 VanDerWaalsContact CZ-N 3.34Å; I533-S572 WeakPolarHBondContact CG2-O 3.35Å; S572-M574 VanDerWaalsContact C-N 3.33Å; S572-M574 PolarHBondContact O-N 2.9Å
573G93Very high94.7Very high13 Ų1320.5 Ų20.513%0.13411%0.113CC..THydrogen-bonded Turntrans72.120.4167.400000115.4E269 V575 Q576E269-G573 WeakPolarHBondContact OE1-CA 3.5Å; E269-G573 PolarHBondContact OE1-N 3.25Å; G573-V575 PolarHBondContact O-N 3Å; G573-Q576 VanDerWaalsContact O-CG 3.31Å; G573-Q576 WeakPolarHBondContact O-CG 3.19Å
574M96.4Very high94.8Very high0 Ų020.5 Ų20.50%011%0.112CC..SBendtrans-59.9128.8173.4-66.3-66.2-82.800109.9I321 I533 T536 I540 V564 L567 R568 R571 S572I321-M574 HydrophobicContact CD1-CE 3.66Å; I533-M574 HydrophobicContact CB-SD 4.2Å; I533-M574 HydrophobicContact CG2-SD 4.17Å; I533-M574 WeakPolarHBondContact O-CA 3.49Å; T536-M574 HydrophobicContact CG2-CE 4.42Å; I540-M574 HydrophobicContact CD1-CE 3.92Å; V564-M574 WeakPolarHBondContact CG1-O 3.49Å; L567-M574 HydrophobicContact CB-CB 3.77Å; L567-M574 HydrophobicContact CB-CG 4.02Å; R568-M574 HydrophobicContact CG-CB 4.12Å; R568-M574 PolarHBondContact NE-O 3.48Å; R571-M574 HydrophobicContact CB-CG 4.09Å; R571-M574 HydrophobicContact CB-SD 4.21Å; R571-M574 HydrophobicContact CG-SD 4.27Å; R571-M574 WeakPolarHBondContact O-CG 3.45Å; S572-M574 VanDerWaalsContact C-N 3.33Å; S572-M574 PolarHBondContact O-N 2.9Å
575V97Very high94.9Very high0 Ų020.5 Ų20.50%011%0.112CC..SBendtrans60.1103.3-167.7-174.30000111.4F262 I533 V564 R568 G573 Q580 Y581F262-V575 HydrophobicContact CE2-CG1 4.45Å; I533-V575 PolarHBondContact O-N 3.41Å; V564-V575 HydrophobicContact CG1-CB 4.03Å; V564-V575 HydrophobicContact CG1-CG2 4.24Å; V564-V575 HydrophobicContact CG2-CB 4.42Å; V564-V575 HydrophobicContact CG2-CG2 3.95Å; R568-V575 PolarHBondContact NH2-O 2.95Å; G573-V575 PolarHBondContact O-N 3Å; V575-Q580 HydrophobicContact CG1-CB 3.82Å; V575-Y581 HydrophobicContact CG1-CD2 4.48Å
576Q94Very high95.2Very high88 Ų8822.3 Ų22.341%0.41112%0.122SC..  trans-97.3-17-164.3-72.4-173.1-69.300115.4I533 G573I533-Q576 HydrophobicContact CD1-CG 4.01Å; I533-Q576 HydrophobicContact CG1-CG 4.02Å; G573-Q576 VanDerWaalsContact O-CG 3.31Å; G573-Q576 WeakPolarHBondContact O-CG 3.19Å
577T93.8Very high95.5Very high60 Ų6022.3 Ų22.337%0.36812%0.122SC..SBendtrans-136.8152-173.463.10000110.1A579 Q580 Y581T577-A579 PolarHBondContact O-N 2.82Å; T577-Q580 WeakPolarHBondContact O-CB 3.47Å; T577-Q580 PolarHBondContact O-N 3.41Å; T577-Q580 VanDerWaalsContact OG1-CG 3.28Å; T577-Q580 WeakPolarHBondContact OG1-CG 3.48Å; T577-Q580 PolarHBondContact OG1-N 2.86Å; T577-Y581 PolarHBondContact O-N 3.36Å
578E93.5Very high95.6Very high67 Ų6722.3 Ų22.331%0.31312%0.122SC..Hα-helixtrans-53.7-41.1171.9-172.3-152.5171.900111.6F258 W259 F262 Q580 Y581 K582F258-E578 HydrophobicContact CB-CG 4.14Å; F258-E578 WeakPolarHBondContact CB-OE1 3.2Å; W259-E578 HydrophobicContact CB-CG 4.45Å; W259-E578 HydrophobicContact CE3-CB 3.73Å; W259-E578 HydrophobicContact CE3-CG 3.95Å; W259-E578 HydrophobicContact CZ3-CB 4.03Å; W259-E578 PolarHBondContact N-OE1 2.94Å; F262-E578 HydrophobicContact CD1-CB 4.13Å; F262-E578 HydrophobicContact CG-CB 4.46Å; E578-Q580 VanDerWaalsContact C-N 3.31Å; E578-Q580 PolarHBondContact O-N 2.84Å; E578-Y581 WeakPolarHBondContact O-CB 3.48Å; E578-Y581 PolarHBondContact O-N 2.96Å; E578-Y581 VanDerWaalsContact O-N 3.08Å; E578-K582 WeakPolarHBondContact O-CB 3.44Å; E578-K582 PolarHBondContact O-N 2.91Å
579A95Very high95.7Very high43 Ų4324.1 Ų24.136%0.35513%0.131SC..Hα-helixtrans-58.7-41177.300000112.6V498 T577 F583V498-A579 HydrophobicContact CG1-CB 4.42Å; V498-A579 WeakPolarHBondContact CG1-O 3.45Å; T577-A579 PolarHBondContact O-N 2.82Å; A579-F583 VanDerWaalsContact O-CB 3.28Å; A579-F583 WeakPolarHBondContact O-CB 3.39Å; A579-F583 PolarHBondContact O-N 2.79Å
580Q96.9Very high95.9Very high18 Ų1827.6 Ų27.68%0.08414%0.143CC..Hα-helixtrans-67.3-42173.9-72.8167.54.600111.6V498 V575 T577 E578 F583 V584V498-Q580 HydrophobicContact CG1-CB 4.47Å; V498-Q580 HydrophobicContact CG1-CG 3.96Å; V575-Q580 HydrophobicContact CG1-CB 3.82Å; T577-Q580 WeakPolarHBondContact O-CB 3.47Å; T577-Q580 PolarHBondContact O-N 3.41Å; T577-Q580 VanDerWaalsContact OG1-CG 3.28Å; T577-Q580 WeakPolarHBondContact OG1-CG 3.48Å; T577-Q580 PolarHBondContact OG1-N 2.86Å; E578-Q580 VanDerWaalsContact C-N 3.31Å; E578-Q580 PolarHBondContact O-N 2.84Å; Q580-F583 WeakPolarHBondContact O-CB 3.48Å; Q580-F583 PolarHBondContact O-N 2.75Å; Q580-V584 PolarHBondContact O-N 3.04Å; Q580-V584 VanDerWaalsContact O-N 3.08Å
581Y96.6Very high96Very high0 Ų027.4 Ų27.40%014%0.142CC..Hα-helixtrans-61.2-49.8177.7-175.1-103.6000111.9F258 E261 F262 L265 I560 R561 V564 V575 T577 E578 F583 V584 Y585F258-Y581 HydrophobicContact CD1-CD1 4.4Å; E261-Y581 HydrophobicContact CB-CE1 3.88Å; E261-Y581 PolarHBondContact OE2-OH 3.01Å; F262-Y581 HydrophobicContact CB-CD1 4.1Å; F262-Y581 HydrophobicContact CB-CG 4.31Å; F262-Y581 HydrophobicContact CD2-CD1 4.43Å; F262-Y581 HydrophobicContact CD2-CD2 4.06Å; F262-Y581 AromaticContact CD2-CG 3.79Å; F262-Y581 HydrophobicContact CD2-CG 3.79Å; F262-Y581 HydrophobicContact CG-CG 4.44Å; L265-Y581 HydrophobicContact CD1-CD2 4.02Å; L265-Y581 HydrophobicContact CD1-CE2 3.52Å; I560-Y581 HydrophobicContact CG2-CD2 4.42Å; I560-Y581 HydrophobicContact CG2-CE2 3.8Å; R561-Y581 WeakPolarHBondContact CA-OH 3.27Å; R561-Y581 VanDerWaalsContact CB-OH 3.32Å; R561-Y581 WeakPolarHBondContact CB-OH 3.39Å; R561-Y581 PolarHBondContact N-OH 2.74Å; V564-Y581 HydrophobicContact CG2-CD2 4.22Å; V564-Y581 HydrophobicContact CG2-CE2 4.17Å; V575-Y581 HydrophobicContact CG1-CD2 4.48Å; T577-Y581 PolarHBondContact O-N 3.36Å; E578-Y581 WeakPolarHBondContact O-CB 3.48Å; E578-Y581 PolarHBondContact O-N 2.96Å; E578-Y581 VanDerWaalsContact O-N 3.08Å; Y581-F583 VanDerWaalsContact C-N 3.26Å; Y581-F583 PolarHBondContact O-N 3.35Å; Y581-V584 WeakPolarHBondContact O-CB 3.14Å; Y581-V584 PolarHBondContact O-N 3.14Å; Y581-V584 VanDerWaalsContact O-N 3.13Å; Y581-Y585 HydrophobicContact CD1-CE2 4.36Å; Y581-Y585 HydrophobicContact CE1-CD2 4.3Å; Y581-Y585 AromaticContact CE1-CE2 3.64Å; Y581-Y585 HydrophobicContact CE1-CE2 3.64Å; Y581-Y585 AromaticContact CZ-CE2 3.81Å; Y581-Y585 PolarHBondContact O-N 3.22Å
582K95.7Very high95.8Very high53 Ų5327.6 Ų27.623%0.2314%0.143CC..Hα-helixtrans-57.3-38.4171.4177.4176.9-178.7169.60112.3F258 E578 V584 Y585 M586F258-K582 HydrophobicContact CD1-CB 4.07Å; F258-K582 HydrophobicContact CD1-CG 4.3Å; F258-K582 HydrophobicContact CD2-CB 4.4Å; F258-K582 HydrophobicContact CD2-CD 3.98Å; F258-K582 HydrophobicContact CD2-CG 4.02Å; F258-K582 HydrophobicContact CE1-CB 4.32Å; F258-K582 HydrophobicContact CE1-CG 4.19Å; F258-K582 HydrophobicContact CE2-CD 4.08Å; F258-K582 HydrophobicContact CE2-CG 3.89Å; F258-K582 HydrophobicContact CG-CB 4.12Å; F258-K582 HydrophobicContact CG-CD 4.46Å; F258-K582 HydrophobicContact CG-CG 4.22Å; F258-K582 HydrophobicContact CZ-CG 3.98Å; E578-K582 WeakPolarHBondContact O-CB 3.44Å; E578-K582 PolarHBondContact O-N 2.91Å; K582-V584 VanDerWaalsContact C-N 3.31Å; K582-V584 PolarHBondContact O-N 2.85Å; K582-Y585 VanDerWaalsContact O-CB 3.31Å; K582-Y585 WeakPolarHBondContact O-CB 3.38Å; K582-Y585 PolarHBondContact O-N 2.82Å; K582-M586 HydrophobicContact CG-SD 4.31Å; K582-M586 WeakPolarHBondContact O-CG 3.49Å; K582-M586 PolarHBondContact O-N 3.39Å
583F97.8Very high95.8Very high1 Ų129.7 Ų29.70%0.00415%0.153CC..Hα-helixtrans-65.9-32.4177.8-175-100.8000113W493 V498 P499 P502 V505 T538 I542 A579 Q580 Y581 Y585 M586 A587W493-F583 HydrophobicContact CH2-CD1 4.48Å; W493-F583 HydrophobicContact CH2-CE1 4.47Å; V498-F583 HydrophobicContact CB-CB 3.88Å; V498-F583 HydrophobicContact CB-CD1 4.4Å; V498-F583 HydrophobicContact CB-CD2 3.75Å; V498-F583 HydrophobicContact CB-CE2 4.41Å; V498-F583 HydrophobicContact CB-CG 3.74Å; V498-F583 HydrophobicContact CG1-CB 3.75Å; V498-F583 HydrophobicContact CG1-CG 4.07Å; V498-F583 HydrophobicContact CG2-CB 3.97Å; V498-F583 HydrophobicContact CG2-CD2 3.71Å; V498-F583 HydrophobicContact CG2-CG 4.04Å; P499-F583 HydrophobicContact CB-CE2 4.08Å; P499-F583 HydrophobicContact CB-CZ 3.88Å; P499-F583 HydrophobicContact CG-CE1 4.36Å; P499-F583 HydrophobicContact CG-CE2 4.4Å; P499-F583 HydrophobicContact CG-CZ 3.88Å; P499-F583 WeakPolarHBondContact O-CE2 3.24Å; P502-F583 HydrophobicContact CB-CE2 4.15Å; P502-F583 HydrophobicContact CB-CZ 4.37Å; P502-F583 HydrophobicContact CG-CE2 4.16Å; V505-F583 HydrophobicContact CB-CE1 4.29Å; V505-F583 HydrophobicContact CB-CZ 4.3Å; V505-F583 HydrophobicContact CG1-CE1 4.46Å; V505-F583 HydrophobicContact CG2-CE1 3.91Å; V505-F583 HydrophobicContact CG2-CZ 3.89Å; T538-F583 HydrophobicContact CG2-CD1 3.92Å; I542-F583 HydrophobicContact CD1-CD1 4.19Å; I542-F583 HydrophobicContact CD1-CE1 4.09Å; A579-F583 VanDerWaalsContact O-CB 3.28Å; A579-F583 WeakPolarHBondContact O-CB 3.39Å; A579-F583 PolarHBondContact O-N 2.79Å; Q580-F583 WeakPolarHBondContact O-CB 3.48Å; Q580-F583 PolarHBondContact O-N 2.75Å; Y581-F583 VanDerWaalsContact C-N 3.26Å; Y581-F583 PolarHBondContact O-N 3.35Å; F583-Y585 VanDerWaalsContact C-N 3.31Å; F583-Y585 PolarHBondContact O-N 2.71Å; F583-M586 PolarHBondContact O-N 3.15Å; F583-A587 HydrophobicContact CE1-CB 4.48Å; F583-A587 WeakPolarHBondContact O-CB 3.47Å; F583-A587 PolarHBondContact O-N 3.27Å
584V98.4Very high95.8Very high0 Ų031.6 Ų31.60%016%0.161CC..Hα-helixtrans-57.1-47.9170.9-179.30000110T538 A541 I542 I545 I560 Q580 Y581 K582 M586 A587 V588T538-V584 HydrophobicContact CG2-CG2 3.86Å; A541-V584 HydrophobicContact CB-CG1 4.3Å; A541-V584 HydrophobicContact CB-CG2 4.24Å; I542-V584 HydrophobicContact CG1-CB 4.33Å; I542-V584 HydrophobicContact CG1-CG1 4.03Å; I542-V584 HydrophobicContact CG1-CG2 4.27Å; I545-V584 HydrophobicContact CD1-CG1 4.03Å; I560-V584 HydrophobicContact CD1-CG1 4.41Å; I560-V584 HydrophobicContact CG1-CG1 4.18Å; I560-V584 HydrophobicContact CG2-CB 4.12Å; I560-V584 HydrophobicContact CG2-CG1 3.75Å; Q580-V584 PolarHBondContact O-N 3.04Å; Q580-V584 VanDerWaalsContact O-N 3.08Å; Y581-V584 WeakPolarHBondContact O-CB 3.14Å; Y581-V584 PolarHBondContact O-N 3.14Å; Y581-V584 VanDerWaalsContact O-N 3.13Å; K582-V584 VanDerWaalsContact C-N 3.31Å; K582-V584 PolarHBondContact O-N 2.85Å; V584-M586 PolarHBondContact O-N 3.43Å; V584-A587 PolarHBondContact O-N 2.94Å; V584-V588 HydrophobicContact CG1-CG2 4.25Å; V584-V588 WeakPolarHBondContact O-CB 3.4Å; V584-V588 VanDerWaalsContact O-CG2 3.23Å; V584-V588 WeakPolarHBondContact O-CG2 3.35Å; V584-V588 PolarHBondContact O-N 2.97Å
585Y97.5Very high95.3Very high0 Ų033.6 Ų33.60%017%0.17CC..Hα-helixtrans-57.4-45.9175-85.7-95.3000112.6I236 R244 V245 L248 F258 E261 I560 Y581 K582 F583 V588 H589I236-Y585 HydrophobicContact CD1-CD1 4.35Å; I236-Y585 HydrophobicContact CD1-CE1 3.39Å; R244-Y585 HydrophobicContact CG-CE1 4.04Å; V245-Y585 HydrophobicContact CG2-CD1 4.22Å; L248-Y585 HydrophobicContact CD1-CD1 4.19Å; L248-Y585 HydrophobicContact CD1-CE1 3.59Å; L248-Y585 HydrophobicContact CD1-CE2 4.28Å; F258-Y585 HydrophobicContact CD1-CD2 4.12Å; F258-Y585 HydrophobicContact CD1-CE2 4.33Å; F258-Y585 HydrophobicContact CE1-CD1 4.14Å; F258-Y585 AromaticContact CE1-CD2 3.61Å; F258-Y585 HydrophobicContact CE1-CD2 3.61Å; F258-Y585 HydrophobicContact CE1-CE2 4.08Å; F258-Y585 AromaticContact CE1-CG 3.65Å; F258-Y585 HydrophobicContact CE1-CG 3.65Å; F258-Y585 HydrophobicContact CZ-CG 4.43Å; E261-Y585 PolarHBondContact OE2-OH 2.7Å; I560-Y585 HydrophobicContact CB-CD2 4.28Å; I560-Y585 HydrophobicContact CB-CE2 3.79Å; I560-Y585 HydrophobicContact CD1-CD1 3.42Å; I560-Y585 VanDerWaalsContact CD1-CD1 3.42Å; I560-Y585 HydrophobicContact CD1-CD2 3.54Å; I560-Y585 HydrophobicContact CD1-CE1 3.61Å; I560-Y585 HydrophobicContact CD1-CE2 3.72Å; I560-Y585 HydrophobicContact CD1-CG 3.39Å; I560-Y585 HydrophobicContact CG1-CD2 4.47Å; I560-Y585 HydrophobicContact CG1-CE2 4.35Å; I560-Y585 HydrophobicContact CG2-CD2 3.89Å; I560-Y585 HydrophobicContact CG2-CE2 3.65Å; Y581-Y585 HydrophobicContact CD1-CE2 4.36Å; Y581-Y585 HydrophobicContact CE1-CD2 4.3Å; Y581-Y585 AromaticContact CE1-CE2 3.64Å; Y581-Y585 HydrophobicContact CE1-CE2 3.64Å; Y581-Y585 AromaticContact CZ-CE2 3.81Å; Y581-Y585 PolarHBondContact O-N 3.22Å; K582-Y585 VanDerWaalsContact O-CB 3.31Å; K582-Y585 WeakPolarHBondContact O-CB 3.38Å; K582-Y585 PolarHBondContact O-N 2.82Å; F583-Y585 VanDerWaalsContact C-N 3.31Å; F583-Y585 PolarHBondContact O-N 2.71Å; Y585-V588 PolarHBondContact O-N 3.34Å; Y585-H589 VanDerWaalsContact O-CB 3.25Å; Y585-H589 WeakPolarHBondContact O-CB 3.4Å; Y585-H589 PolarHBondContact O-N 3.44Å
586M97.2Very high94.7Very high68 Ų6834.7 Ų34.734%0.33518%0.178SC..Hα-helixtrans-64.3-41.9-179.6-65.8177.769.200112.5P502 K582 F583 V584 Y590P502-M586 HydrophobicContact CG-CB 3.91Å; P502-M586 HydrophobicContact CG-CE 4.3Å; K582-M586 HydrophobicContact CG-SD 4.31Å; K582-M586 WeakPolarHBondContact O-CG 3.49Å; K582-M586 PolarHBondContact O-N 3.39Å; F583-M586 PolarHBondContact O-N 3.15Å; V584-M586 PolarHBondContact O-N 3.43Å; M586-Y590 WeakPolarHBondContact O-CB 3.28Å; M586-Y590 PolarHBondContact O-N 3.33Å
587A98.2Very high94.3Very high0 Ų036 Ų360%018%0.182CC..Hα-helixtrans-67.8-43.5178.100000112.1P502 V506 I542 F583 V584 Y590 Y591P502-A587 HydrophobicContact CB-CB 4.2Å; V506-A587 HydrophobicContact CG2-CB 4.18Å; V506-A587 WeakPolarHBondContact CG2-O 3.41Å; I542-A587 HydrophobicContact CD1-CB 3.59Å; I542-A587 HydrophobicContact CG1-CB 3.97Å; I542-A587 HydrophobicContact CG2-CB 4.13Å; F583-A587 HydrophobicContact CE1-CB 4.48Å; F583-A587 WeakPolarHBondContact O-CB 3.47Å; F583-A587 PolarHBondContact O-N 3.27Å; V584-A587 PolarHBondContact O-N 2.94Å; A587-Y590 PolarHBondContact O-N 3.18Å; A587-Y591 PolarHBondContact O-N 3.47Å
588V97.4Very high93.8Very high0 Ų038.5 Ų38.50%019%0.192CC..Hα-helixtrans-64.3-41.8176.11740000110.7I241 I545 I558 V584 Y585 Y591 I592I241-V588 HydrophobicContact CD1-CB 4.07Å; I241-V588 HydrophobicContact CD1-CG1 3.59Å; I545-V588 HydrophobicContact CB-CG2 3.99Å; I545-V588 HydrophobicContact CD1-CG2 4.03Å; I545-V588 HydrophobicContact CG2-CB 4.36Å; I545-V588 HydrophobicContact CG2-CG1 3.64Å; I545-V588 HydrophobicContact CG2-CG2 3.68Å; I558-V588 HydrophobicContact CD1-CG1 3.75Å; V584-V588 HydrophobicContact CG1-CG2 4.25Å; V584-V588 WeakPolarHBondContact O-CB 3.4Å; V584-V588 VanDerWaalsContact O-CG2 3.23Å; V584-V588 WeakPolarHBondContact O-CG2 3.35Å; V584-V588 PolarHBondContact O-N 2.97Å; Y585-V588 PolarHBondContact O-N 3.34Å; V588-Y591 PolarHBondContact O-N 3.41Å; V588-I592 HydrophobicContact CG1-CD1 3.59Å; V588-I592 HydrophobicContact CG1-CG1 4.39Å; V588-I592 WeakPolarHBondContact O-CB 3.33Å; V588-I592 WeakPolarHBondContact O-CD1 3.36Å; V588-I592 VanDerWaalsContact O-CG1 3.28Å; V588-I592 WeakPolarHBondContact O-CG1 3.25Å; V588-I592 PolarHBondContact O-N 3.02Å
589H96.5Very high93Very high48 Ų4837.2 Ų37.222%0.22219%0.189CC..Hα-helixtrans-59.7-49.4174.5174.1-151.8000111.7I241 D242 V245 Y585 Y591 I592 D593I241-H589 HydrophobicContact CD1-CB 4.14Å; I241-H589 HydrophobicContact CG1-CB 4.33Å; I241-H589 HydrophobicContact CG2-CB 3.99Å; D242-H589 IonicContact OD1-CE1 3.76Å; D242-H589 PolarHBondContact OD1-CE1 3Å; D242-H589 IonicContact OD1-NE2 3.68Å; V245-H589 HydrophobicContact CG2-CB 4.46Å; Y585-H589 VanDerWaalsContact O-CB 3.25Å; Y585-H589 WeakPolarHBondContact O-CB 3.4Å; Y585-H589 PolarHBondContact O-N 3.44Å; H589-Y591 VanDerWaalsContact C-N 3.3Å; H589-Y591 PolarHBondContact O-N 3.22Å; H589-I592 PolarHBondContact O-N 3.31Å; H589-D593 PolarHBondContact O-N 3.21Å
590Y96.7Very high92.1Very high81 Ų8139.9 Ų39.932%0.31819%0.194SC..Hα-helixtrans-56.1-45.3177.1177.7-84.1000112V506 M586 A587 T594V506-Y590 HydrophobicContact CB-CD1 4.07Å; V506-Y590 HydrophobicContact CB-CE1 4.32Å; V506-Y590 HydrophobicContact CG1-CD1 4.19Å; V506-Y590 HydrophobicContact CG1-CE1 4.36Å; V506-Y590 HydrophobicContact CG2-CD1 3.98Å; M586-Y590 WeakPolarHBondContact O-CB 3.28Å; M586-Y590 PolarHBondContact O-N 3.33Å; A587-Y590 PolarHBondContact O-N 3.18Å; Y590-T594 WeakPolarHBondContact O-CB 3.36Å; Y590-T594 PolarHBondContact O-N 3.3Å; Y590-T594 VanDerWaalsContact O-N 3.08Å; Y590-T594 PolarHBondContact O-OG1 2.87Å
591Y96.3Very high91.2Very high14 Ų1442.8 Ų42.86%0.05521%0.208CC..Hα-helixtrans-63.5-46.3177.5176.5-97.4000111.8V506 E510 L546 V549 A587 V588 H589 D593 T594 F595V506-Y591 HydrophobicContact CG1-CD2 3.77Å; V506-Y591 HydrophobicContact CG1-CG 4.41Å; E510-Y591 WeakPolarHBondContact OE1-CE2 3.48Å; L546-Y591 HydrophobicContact CB-CE1 4.48Å; L546-Y591 HydrophobicContact CD1-CD2 3.97Å; L546-Y591 HydrophobicContact CD1-CE2 4.39Å; L546-Y591 HydrophobicContact CD1-CG 4.2Å; L546-Y591 HydrophobicContact CD2-CD1 3.56Å; L546-Y591 HydrophobicContact CD2-CD2 4.07Å; L546-Y591 HydrophobicContact CD2-CE1 4.23Å; L546-Y591 HydrophobicContact CD2-CG 3.44Å; L546-Y591 VanDerWaalsContact CD2-CG 3.44Å; L546-Y591 HydrophobicContact CG-CD2 4.48Å; L546-Y591 HydrophobicContact CG-CG 4.3Å; V549-Y591 HydrophobicContact CB-CE1 4.12Å; V549-Y591 HydrophobicContact CG1-CD1 4.41Å; V549-Y591 HydrophobicContact CG1-CE1 3.9Å; A587-Y591 PolarHBondContact O-N 3.47Å; V588-Y591 PolarHBondContact O-N 3.41Å; H589-Y591 VanDerWaalsContact C-N 3.3Å; H589-Y591 PolarHBondContact O-N 3.22Å; Y591-D593 VanDerWaalsContact C-N 3.35Å; Y591-D593 PolarHBondContact O-N 3.46Å; Y591-T594 PolarHBondContact O-N 3.3Å; Y591-F595 HydrophobicContact CD1-CB 4.46Å; Y591-F595 HydrophobicContact CE1-CB 4.19Å; Y591-F595 HydrophobicContact CE1-CG 4.35Å; Y591-F595 VanDerWaalsContact O-CB 3.27Å; Y591-F595 WeakPolarHBondContact O-CB 3.13Å; Y591-F595 PolarHBondContact O-N 2.84Å
592I92.1Very high90Very high4 Ų449 Ų492%0.02123%0.232CC..Hα-helixtrans-61.4-42.9-179.6-74161.8000111.6P238 I241 V549 L554 I558 V588 H589 F595 S596P238-I592 HydrophobicContact CB-CD1 3.62Å; P238-I592 HydrophobicContact CB-CG1 4.04Å; P238-I592 HydrophobicContact CB-CG2 4.26Å; P238-I592 HydrophobicContact CG-CD1 4.5Å; P238-I592 WeakPolarHBondContact O-CG2 3.37Å; I241-I592 HydrophobicContact CB-CD1 4.33Å; I241-I592 HydrophobicContact CD1-CD1 3.87Å; I241-I592 HydrophobicContact CG2-CB 4.45Å; I241-I592 HydrophobicContact CG2-CD1 3.93Å; I241-I592 HydrophobicContact CG2-CG2 4.33Å; V549-I592 HydrophobicContact CG1-CG1 4.43Å; L554-I592 HydrophobicContact CD2-CB 4.46Å; L554-I592 HydrophobicContact CD2-CG1 4.43Å; L554-I592 HydrophobicContact CD2-CG2 3.75Å; I558-I592 HydrophobicContact CD1-CD1 4.14Å; V588-I592 HydrophobicContact CG1-CD1 3.59Å; V588-I592 HydrophobicContact CG1-CG1 4.39Å; V588-I592 WeakPolarHBondContact O-CB 3.33Å; V588-I592 WeakPolarHBondContact O-CD1 3.36Å; V588-I592 VanDerWaalsContact O-CG1 3.28Å; V588-I592 WeakPolarHBondContact O-CG1 3.25Å; V588-I592 PolarHBondContact O-N 3.02Å; H589-I592 PolarHBondContact O-N 3.31Å; I592-F595 PolarHBondContact O-N 2.84Å; I592-S596 VanDerWaalsContact O-CB 3.25Å; I592-S596 WeakPolarHBondContact O-CB 3.29Å; I592-S596 PolarHBondContact O-N 2.84Å; I592-S596 PolarHBondContact O-OG 2.88Å
593D92.3Very high88.7Confident66 Ų6648.2 Ų48.235%0.35323%0.229SC..Hα-helixtrans-62-45.6176.4179.451000111H589 Y591 S596 K597H589-D593 PolarHBondContact O-N 3.21Å; Y591-D593 VanDerWaalsContact C-N 3.35Å; Y591-D593 PolarHBondContact O-N 3.46Å; D593-S596 PolarHBondContact O-N 2.96Å; D593-K597 WeakPolarHBondContact O-CG 3.3Å; D593-K597 PolarHBondContact O-N 3.44Å; D593-K597 VanDerWaalsContact O-N 3.09Å; D593-K597 WeakPolarHBondContact OD1-CE 3.39Å; D593-K597 IonicContact OD1-NZ 3.77Å; D593-K597 PolarHBondContact OD1-NZ 3.43Å; D593-K597 WeakPolarHBondContact OD2-CE 3.28Å; D593-K597 IonicContact OD2-NZ 3.42Å; D593-K597 PolarHBondContact OD2-NZ 3.36Å
594T91.4Very high87.5Confident52 Ų5253.9 Ų53.932%0.31925%0.25SS..Hα-helixtrans-61.1-48.2176-55.80000111.6Y590 Y591 S596 K597 L598Y590-T594 WeakPolarHBondContact O-CB 3.36Å; Y590-T594 PolarHBondContact O-N 3.3Å; Y590-T594 VanDerWaalsContact O-N 3.08Å; Y590-T594 PolarHBondContact O-OG1 2.87Å; Y591-T594 PolarHBondContact O-N 3.3Å; T594-S596 VanDerWaalsContact C-N 3.35Å; T594-S596 PolarHBondContact O-N 2.98Å; T594-K597 PolarHBondContact O-N 3.16Å; T594-L598 HydrophobicContact CG2-CD1 4.35Å; T594-L598 WeakPolarHBondContact O-CG 3.47Å; T594-L598 PolarHBondContact O-N 3.16Å
595F86.5Confident86.2Confident43 Ų4358 Ų5819%0.18927%0.272CS..Hα-helixtrans-63.8-39.9179.5-171.9-106.1000111.7V549 L554 Y591 I592 K597 L598 V599V549-F595 HydrophobicContact CG1-CD1 4.29Å; L554-F595 HydrophobicContact CD1-CD1 4.21Å; L554-F595 HydrophobicContact CD2-CD1 3.81Å; L554-F595 HydrophobicContact CD2-CE1 4.48Å; L554-F595 HydrophobicContact CG-CD1 3.78Å; L554-F595 HydrophobicContact CG-CE1 4.08Å; Y591-F595 HydrophobicContact CD1-CB 4.46Å; Y591-F595 HydrophobicContact CE1-CB 4.19Å; Y591-F595 HydrophobicContact CE1-CG 4.35Å; Y591-F595 VanDerWaalsContact O-CB 3.27Å; Y591-F595 WeakPolarHBondContact O-CB 3.13Å; Y591-F595 PolarHBondContact O-N 2.84Å; I592-F595 PolarHBondContact O-N 2.84Å; F595-K597 PolarHBondContact O-N 2.84Å; F595-L598 PolarHBondContact O-N 3.41Å; F595-V599 HydrophobicContact CD1-CG2 4.12Å; F595-V599 HydrophobicContact CE1-CG2 3.83Å; F595-V599 HydrophobicContact CE2-CG2 4.45Å; F595-V599 HydrophobicContact CZ-CG2 4.01Å; F595-V599 VanDerWaalsContact O-CG2 3.3Å; F595-V599 WeakPolarHBondContact O-CG2 3.47Å; F595-V599 PolarHBondContact O-N 3.04Å
596S84.4Confident84.8Confident22 Ų2262 Ų6215%0.15429%0.29CS..Hα-helixtrans-60.1-44.1175.5-61.60000111.9L554 I592 D593 T594 V599 Q600L554-S596 WeakPolarHBondContact CD1-OG 3.43Å; I592-S596 VanDerWaalsContact O-CB 3.25Å; I592-S596 WeakPolarHBondContact O-CB 3.29Å; I592-S596 PolarHBondContact O-N 2.84Å; I592-S596 PolarHBondContact O-OG 2.88Å; D593-S596 PolarHBondContact O-N 2.96Å; T594-S596 VanDerWaalsContact C-N 3.35Å; T594-S596 PolarHBondContact O-N 2.98Å; S596-V599 PolarHBondContact O-N 3.21Å; S596-Q600 VanDerWaalsContact O-CG 3.26Å; S596-Q600 WeakPolarHBondContact O-CG 3.37Å; S596-Q600 PolarHBondContact O-N 2.89Å
597K86.4Confident83.2Confident117 Ų11762 Ų6251%0.50929%0.289SS..Hα-helixtrans-64.3-42.7175.9-70.8165.7179.4165.90111.9D593 T594 F595 Q600 E601D593-K597 WeakPolarHBondContact O-CG 3.3Å; D593-K597 PolarHBondContact O-N 3.44Å; D593-K597 VanDerWaalsContact O-N 3.09Å; D593-K597 WeakPolarHBondContact OD1-CE 3.39Å; D593-K597 IonicContact OD1-NZ 3.77Å; D593-K597 PolarHBondContact OD1-NZ 3.43Å; D593-K597 WeakPolarHBondContact OD2-CE 3.28Å; D593-K597 IonicContact OD2-NZ 3.42Å; D593-K597 PolarHBondContact OD2-NZ 3.36Å; T594-K597 PolarHBondContact O-N 3.16Å; F595-K597 PolarHBondContact O-N 2.84Å; K597-Q600 PolarHBondContact O-N 3.14Å; K597-E601 PolarHBondContact O-N 3.38Å
598L83.5Confident81.7Confident111 Ų11165.2 Ų65.258%0.58131%0.309SS*.Hα-helixtrans-63.2-43.8177.1-71.5174.3000112.4T594 F595 Q600 E601 Y602T594-L598 HydrophobicContact CG2-CD1 4.35Å; T594-L598 WeakPolarHBondContact O-CG 3.47Å; T594-L598 PolarHBondContact O-N 3.16Å; F595-L598 PolarHBondContact O-N 3.41Å; L598-Q600 VanDerWaalsContact C-N 3.3Å; L598-Q600 PolarHBondContact O-N 3.15Å; L598-E601 PolarHBondContact O-N 2.94Å; L598-Y602 WeakPolarHBondContact O-CB 3.47Å; L598-Y602 PolarHBondContact O-N 2.99Å
599V76.1Confident79.7Confident40 Ų4066.7 Ų66.724%0.24232%0.324CS..Hα-helixtrans-62.4-39.6176.2170.90000110.9F595 S596 K603F595-V599 HydrophobicContact CD1-CG2 4.12Å; F595-V599 HydrophobicContact CE1-CG2 3.83Å; F595-V599 HydrophobicContact CE2-CG2 4.45Å; F595-V599 HydrophobicContact CZ-CG2 4.01Å; F595-V599 VanDerWaalsContact O-CG2 3.3Å; F595-V599 WeakPolarHBondContact O-CG2 3.47Å; F595-V599 PolarHBondContact O-N 3.04Å; S596-V599 PolarHBondContact O-N 3.21Å; V599-K603 HydrophobicContact CG1-CD 4.06Å; V599-K603 WeakPolarHBondContact O-CB 3.4Å; V599-K603 VanDerWaalsContact O-CG 3.24Å; V599-K603 WeakPolarHBondContact O-CG 3.34Å; V599-K603 PolarHBondContact O-N 2.86Å
600Q77.1Confident77.6Confident99 Ų9973.7 Ų73.746%0.46335%0.348SS..Hα-helixtrans-64.1-45.5176-72.5168.521.600111.8F29 S596 K597 L598 R604F29-Q600 HydrophobicContact CZ-CB 4.39Å; F29-Q600 HydrophobicContact CZ-CG 4.26Å; S596-Q600 VanDerWaalsContact O-CG 3.26Å; S596-Q600 WeakPolarHBondContact O-CG 3.37Å; S596-Q600 PolarHBondContact O-N 2.89Å; K597-Q600 PolarHBondContact O-N 3.14Å; L598-Q600 VanDerWaalsContact C-N 3.3Å; L598-Q600 PolarHBondContact O-N 3.15Å; Q600-R604 WeakPolarHBondContact O-CB 3.42Å; Q600-R604 PolarHBondContact O-N 2.71Å
601E76.1Confident75.1Confident80 Ų8077.8 Ų77.837%0.37437%0.37SS..Hα-helixtrans-68.7-42.4180-174.858.3-161.600112.4K597 L598 K603 R604 I605K597-E601 PolarHBondContact O-N 3.38Å; L598-E601 PolarHBondContact O-N 2.94Å; E601-K603 VanDerWaalsContact C-N 3.29Å; E601-K603 PolarHBondContact O-N 2.84Å; E601-R604 WeakPolarHBondContact O-CB 3.21Å; E601-R604 PolarHBondContact O-N 2.7Å; E601-R604 IonicContact OE1-CZ 3.79Å; E601-R604 IonicContact OE1-NE 3.42Å; E601-R604 PolarHBondContact OE1-NE 2.69Å; E601-R604 VanDerWaalsContact OE1-NE 3.13Å; E601-R604 IonicContact OE1-NH2 2.7Å; E601-R604 PolarHBondContact OE1-NH2 3.21Å; E601-R604 IonicContact OE2-CZ 3.47Å; E601-R604 IonicContact OE2-NE 3.85Å; E601-R604 PolarHBondContact OE2-NE 3.1Å; E601-R604 IonicContact OE2-NH2 3.43Å; E601-I605 HydrophobicContact CG-CD1 4.01Å; E601-I605 HydrophobicContact CG-CG1 4.48Å; E601-I605 WeakPolarHBondContact O-CG1 3.49Å; E601-I605 PolarHBondContact O-N 3.3Å
602Y71.6Confident72.7Confident130 Ų13087 Ų8751%0.5141%0.407SS..Hα-helixtrans-56.5-47176.9176.3-93.3000111.2L598 I605 E606L598-Y602 WeakPolarHBondContact O-CB 3.47Å; L598-Y602 PolarHBondContact O-N 2.99Å; Y602-I605 WeakPolarHBondContact O-CB 3.23Å; Y602-I605 PolarHBondContact O-N 2.93Å; Y602-E606 HydrophobicContact CD1-CG 4.39Å; Y602-E606 HydrophobicContact CE1-CG 3.83Å; Y602-E606 WeakPolarHBondContact CE1-OE1 3.25Å; Y602-E606 PolarHBondContact O-N 3.35Å; Y602-E606 PolarHBondContact OH-OE1 3.07Å
603K69.7Low70.6Confident37 Ų3792 Ų9216%0.16144%0.438CS..Hα-helixtrans-73.2-30.6-179.7-62.9176.5-179.6176.60112.2F29 V599 E601 I605 E606 E607F29-K603 HydrophobicContact CB-CB 4.25Å; F29-K603 HydrophobicContact CB-CD 4.12Å; F29-K603 HydrophobicContact CD1-CB 3.08Å; F29-K603 HydrophobicContact CD1-CD 3.79Å; F29-K603 HydrophobicContact CD1-CG 4.09Å; F29-K603 HydrophobicContact CD2-CB 4.08Å; F29-K603 HydrophobicContact CD2-CD 3.11Å; F29-K603 HydrophobicContact CD2-CG 4.25Å; F29-K603 HydrophobicContact CE1-CB 3.21Å; F29-K603 HydrophobicContact CE1-CD 3.9Å; F29-K603 HydrophobicContact CE1-CG 4.23Å; F29-K603 HydrophobicContact CE2-CB 4.19Å; F29-K603 HydrophobicContact CE2-CD 3.25Å; F29-K603 HydrophobicContact CE2-CG 4.39Å; F29-K603 HydrophobicContact CG-CB 3.51Å; F29-K603 HydrophobicContact CG-CD 3.35Å; F29-K603 HydrophobicContact CG-CG 4.06Å; F29-K603 HydrophobicContact CZ-CB 3.77Å; F29-K603 HydrophobicContact CZ-CD 3.64Å; F29-K603 HydrophobicContact CZ-CG 4.36Å; V599-K603 HydrophobicContact CG1-CD 4.06Å; V599-K603 WeakPolarHBondContact O-CB 3.4Å; V599-K603 VanDerWaalsContact O-CG 3.24Å; V599-K603 WeakPolarHBondContact O-CG 3.34Å; V599-K603 PolarHBondContact O-N 2.86Å; E601-K603 VanDerWaalsContact C-N 3.29Å; E601-K603 PolarHBondContact O-N 2.84Å; K603-I605 VanDerWaalsContact C-N 3.33Å; K603-E606 PolarHBondContact O-N 2.81Å; K603-E607 WeakPolarHBondContact O-CG 3.48Å; K603-E607 PolarHBondContact O-N 2.82Å; K603-E607 VanDerWaalsContact O-N 3.11Å
604R72.6Confident68.1Low120 Ų12095.5 Ų95.545%0.45346%0.456SS..Hα-helixtrans-60.4-42.8167.9-167.9-169.579.881.93.7111.3Q600 E601 E607 T608Q600-R604 WeakPolarHBondContact O-CB 3.42Å; Q600-R604 PolarHBondContact O-N 2.71Å; E601-R604 WeakPolarHBondContact O-CB 3.21Å; E601-R604 PolarHBondContact O-N 2.7Å; E601-R604 IonicContact OE1-CZ 3.79Å; E601-R604 IonicContact OE1-NE 3.42Å; E601-R604 PolarHBondContact OE1-NE 2.69Å; E601-R604 VanDerWaalsContact OE1-NE 3.13Å; E601-R604 IonicContact OE1-NH2 2.7Å; E601-R604 PolarHBondContact OE1-NH2 3.21Å; E601-R604 IonicContact OE2-CZ 3.47Å; E601-R604 IonicContact OE2-NE 3.85Å; E601-R604 PolarHBondContact OE2-NE 3.1Å; E601-R604 IonicContact OE2-NH2 3.43Å; R604-E607 WeakPolarHBondContact O-CB 3.32Å; R604-E607 PolarHBondContact O-N 2.79Å; R604-T608 PolarHBondContact O-N 2.71Å; R604-T608 PolarHBondContact O-OG1 3.08Å
605I70.6Confident65.5Low87 Ų87100 Ų10045%0.44648%0.476SS..Hα-helixtrans-65.6-39.9176.2-68.2166.1000111E601 Y602 K603 E607 T608 G609E601-I605 HydrophobicContact CG-CD1 4.01Å; E601-I605 HydrophobicContact CG-CG1 4.48Å; E601-I605 WeakPolarHBondContact O-CG1 3.49Å; E601-I605 PolarHBondContact O-N 3.3Å; Y602-I605 WeakPolarHBondContact O-CB 3.23Å; Y602-I605 PolarHBondContact O-N 2.93Å; K603-I605 VanDerWaalsContact C-N 3.33Å; I605-E607 PolarHBondContact O-N 3.29Å; I605-T608 PolarHBondContact O-N 2.71Å; I605-G609 VanDerWaalsContact O-CA 3.25Å; I605-G609 WeakPolarHBondContact O-CA 3.47Å; I605-G609 PolarHBondContact O-N 3.09Å
606E67.2Low63Low83 Ų83106.7 Ų106.739%0.38850%0.501SS..Hα-helixtrans-61.3-32.3173.8-76.1-170.9154.800112.5Y602 K603Y602-E606 HydrophobicContact CD1-CG 4.39Å; Y602-E606 HydrophobicContact CE1-CG 3.83Å; Y602-E606 WeakPolarHBondContact CE1-OE1 3.25Å; Y602-E606 PolarHBondContact O-N 3.35Å; Y602-E606 PolarHBondContact OH-OE1 3.07Å; K603-E606 PolarHBondContact O-N 2.81Å
607E63.9Low60.7Low68 Ų68116.1 Ų116.132%0.31853%0.534SS..Hα-helixtrans-72.7-49.1174.7-70.2-178.2169.800112.5F29 D30 R50 K603 R604 I605F29-E607 WeakPolarHBondContact CA-OE1 3.43Å; D30-E607 PolarHBondContact N-OE1 3.47Å; R50-E607 IonicContact CZ-OE1 3.74Å; R50-E607 VanDerWaalsContact CZ-OE1 3.27Å; R50-E607 IonicContact CZ-OE2 3.22Å; R50-E607 IonicContact NE-OE1 3.26Å; R50-E607 IonicContact NH1-OE1 3.25Å; R50-E607 IonicContact NH2-OE1 2.72Å; R50-E607 PolarHBondContact NH2-OE1 3.03Å; R50-E607 IonicContact NH2-OE2 3.45Å; R50-E607 PolarHBondContact NH2-OE2 3.16Å; K603-E607 WeakPolarHBondContact O-CG 3.48Å; K603-E607 PolarHBondContact O-N 2.82Å; K603-E607 VanDerWaalsContact O-N 3.11Å; R604-E607 WeakPolarHBondContact O-CB 3.32Å; R604-E607 PolarHBondContact O-N 2.79Å; I605-E607 PolarHBondContact O-N 3.29Å
608T67.2Low58.4Low68 Ų68114 Ų11442%0.41753%0.531SS..Hα-helixtrans-80.6-29.7-177.257.90000113.5R604 I605 R610 E611R604-T608 PolarHBondContact O-N 2.71Å; R604-T608 PolarHBondContact O-OG1 3.08Å; I605-T608 PolarHBondContact O-N 2.71Å; T608-R610 PolarHBondContact O-N 3.31Å; T608-R610 VanDerWaalsContact O-N 3.12Å; T608-E611 PolarHBondContact O-N 3.27Å; T608-E611 VanDerWaalsContact O-N 3.15Å
609G56.2Low56.7Low30 Ų30114 Ų11431%0.30954%0.54SS..G310 helixtrans-72.3-1.4-173.200000114.8I605 E611 Y612I605-G609 VanDerWaalsContact O-CA 3.25Å; I605-G609 WeakPolarHBondContact O-CA 3.47Å; I605-G609 PolarHBondContact O-N 3.09Å; G609-E611 PolarHBondContact O-N 3.33Å; G609-Y612 VanDerWaalsContact O-CD2 3.31Å; G609-Y612 WeakPolarHBondContact O-CD2 3.4Å
610R50.6Low55.3Low196 Ų196119.3 Ų119.374%0.7456%0.563SS**G310 helixtrans-75.1-5.6166.4-68-167.7-174.1-178.38.6113.3T608 Y612T608-R610 PolarHBondContact O-N 3.31Å; T608-R610 VanDerWaalsContact O-N 3.12Å; R610-Y612 PolarHBondContact O-N 2.89Å
611E46.1Very low53.4Low166 Ų166118.8 Ų118.878%0.77658%0.576SS**G310 helixtrans-88.315.3177.7-71.5-171.3158.800115.5T608 G609 T613T608-E611 PolarHBondContact O-N 3.27Å; T608-E611 VanDerWaalsContact O-N 3.15Å; G609-E611 PolarHBondContact O-N 3.33Å; E611-T613 VanDerWaalsContact C-N 3.35Å; E611-T613 PolarHBondContact O-N 2.77Å
612Y44.1Very low51.6Low209 Ų209119.2 Ų119.282%0.8259%0.593SS**  trans-8081.1166.6-66.5-75.2000111.1G609 R610G609-Y612 VanDerWaalsContact O-CD2 3.31Å; G609-Y612 WeakPolarHBondContact O-CD2 3.4Å; R610-Y612 PolarHBondContact O-N 2.89Å
613T48.1Very low50.3Low109 Ų109117.6 Ų117.667%0.66960%0.6SS**  trans-119.18.1169.747.20000115.2E611E611-T613 VanDerWaalsContact C-N 3.35Å; E611-T613 PolarHBondContact O-N 2.77Å
614N40.2Very low48.6Very low138 Ų138121.2 Ų121.274%0.73863%0.63SS**  trans-122.127.5-175.1-67.4-23.9000116.7R616N614-R616 PolarHBondContact O-N 2.82Å
615I37.1Very low46.7Very low146 Ų146124.5 Ų124.575%0.74965%0.651SS**  trans-8775.4149.4-51.8178.1000106.7Y617I615-Y617 HydrophobicContact CG2-CE2 4.48Å; I615-Y617 PolarHBondContact O-N 2.8Å
616R33.7Very low44.7Very low185 Ų185129.1 Ų129.170%0.69868%0.675SS**  trans-70.9114.6157.5-69.2-175-179.7-172-0.2105.6N614 T618N614-R616 PolarHBondContact O-N 2.82Å; R616-T618 HydrophobicContact CB-CG2 3.77Å; R616-T618 PolarHBondContact O-N 2.86Å
617Y36.8Very low43Very low219 Ų219129.3 Ų129.386%0.85969%0.691SS**  trans-6385.3152.7-77.5-84.1000105.7I615 S619I615-Y617 HydrophobicContact CG2-CE2 4.48Å; I615-Y617 PolarHBondContact O-N 2.8Å; Y617-S619 PolarHBondContact O-N 2.93Å
618T38.3Very low41.4Very low72 Ų72132.1 Ų132.144%0.44272%0.715SS.*  trans-76.595.8175.234.70000106.9R616 E620 A621R616-T618 HydrophobicContact CB-CG2 3.77Å; R616-T618 PolarHBondContact O-N 2.86Å; T618-E620 PolarHBondContact O-N 3.39Å; T618-E620 VanDerWaalsContact O-N 3.15Å; T618-A621 PolarHBondContact O-N 3.25Å
619S47.1Very low39.6Very low111 Ų111137.1 Ų137.178%0.77674%0.737SS**THydrogen-bonded Turntrans-59.8-4.1152.943.70000112.3Y617Y617-S619 PolarHBondContact O-N 2.93Å
620E46Very low38.2Very low152 Ų152140.8 Ų140.871%0.7176%0.758SS**THydrogen-bonded Turntrans-93.5-5.2179.3-70.1176.3160.800114.8T618 A622T618-E620 PolarHBondContact O-N 3.39Å; T618-E620 VanDerWaalsContact O-N 3.15Å; E620-A622 PolarHBondContact O-N 2.96Å
621A38.7Very low37.2Very low89 Ų89137.1 Ų137.174%0.73676%0.76SS**THydrogen-bonded Turntrans-76.9-6.7172.300000113.5T618T618-A621 PolarHBondContact O-N 3.25Å
622A38.7Very low36.4Very low89 Ų89133.8 Ų133.874%0.73676%0.761SS**THydrogen-bonded Turntrans-99.4-9.4-178.800000114.7E620E620-A622 PolarHBondContact O-N 2.96Å
623S43.8Very low35.5Very low96 Ų96127.6 Ų127.667%0.67175%0.753SS**SBendtrans-138.566.1-171.8-71.70000111.9
624S33.6Very low34.3Very low112 Ų112131.9 Ų131.978%0.78376%0.763SS**SBendtrans-178.1127.4153-79.20000109.3
625Q33.4Very low33.6Very low190 Ų190132.3 Ų132.389%0.88877%0.765SS**  trans90.557.1175.1-47.4-1731500116.7
626L28.7Very low32.8Very low183 Ų183132.9 Ų132.996%0.95876%0.764SS**  trans-106.391.5138.8-75.1170.1000107.3
627A31.2Very low32.4Very low87 Ų87130.4 Ų130.472%0.71977%0.765SS**PPolyproline II helixtrans-87143.7160.800000108.5
628P29.6Very low32Very low127 Ų127129 Ų12983%0.82577%0.766SS**PPolyproline II helixtrans-90.4125.9-154.827.4-18.6000111.9
629I29.1Very low31.1Very low173 Ų173130.4 Ų130.489%0.88778%0.779SS**PPolyproline II helixtrans-97.6119.1159.6-61.3177.6000107.2
630S27.3Very low30.3Very low107 Ų107136.2 Ų136.275%0.74879%0.786SS**PPolyproline II helixtrans-56.3155.6-179.8-170.70000113.5
631P30.2Very low29.3Very low120 Ų120132.3 Ų132.378%0.77979%0.786SS**PPolyproline II helixtrans-95.5132.4-162.633-24.7000114.1
632A28.3Very low28.6Very low96 Ų96139.3 Ų139.379%0.79379%0.793SS**  trans-134.696.7154.400000105.3
633A25.6Very low28Very low79 Ų79144.4 Ų144.465%0.65380%0.802SS**  65.2108.978.300000112.4
634F22.1Very low26.9Very low198 Ų198145.9 Ų145.987%0.86881%0.807SS**  trans72.6132.7166.7-62.8-94.4000115.3
635D25.8Very low26.6Very low147 Ų147152.5 Ų152.579%0.78682%0.815SS**  cis-153.8148.944.3-155.6-2.5000112.5
636E21.2Very low26.1Very low158 Ų158149.3 Ų149.374%0.73881%0.812SS**  trans-73.3170.8171.6-73.7177.7135.400110.5
637N24.2Very low26.4Very low134 Ų134146.4 Ų146.472%0.71780%0.804SS**  trans84.198.5169.1-52.9-51.7000116.8
638Q28.2Very low26Very low188 Ų188147.6 Ų147.688%0.87981%0.808SS**  -156105.8110.5-106.2168.348.500111.1
639S21.3Very low26Very low102 Ų102147.4 Ų147.471%0.71381%0.809SS**  trans-88.3123.1166560000109.7
640Y29.6Very low26Very low234 Ų234144 Ų14492%0.91880%0.801SS**  trans-154.2126.9150.4-79.7-79.6000103.5
641G25.5Very low26.1Very low69 Ų69144.4 Ų144.471%0.71180%0.803SS**  cis145.593.82100000106.2
642R22.3Very low26.1Very low236 Ų236144.2 Ų144.289%0.89180%0.802SS**  trans41.7110.8142.5-155.2-177.7-141.8-152.85118.4
643Q26.7Very low26.1Very low197 Ų197148.1 Ų148.192%0.92181%0.809SS**  -157.3121.7126.6-110.4173.531.300112.2
644T22Very low26.3Very low126 Ų126153.1 Ų153.177%0.77382%0.819SS**  trans-80.2129.7174.743.60000111.3
645R26.9Very low26.5Very low251 Ų251153.9 Ų153.995%0.94782%0.816SS**  trans-162.4122143-111.4174.9-177.6-168.70110.9
646C23.2Very low26.6Very low123 Ų123155.5 Ų155.583%0.83182%0.821SS**  trans-74.8-177.7176.6-50.30000112.4
647P33.2Very low27.1Very low122 Ų122155.8 Ų155.879%0.79282%0.822SS**  -115.3159.6-73.433.8-19.6000112.1
648S24.4Very low27.4Very low113 Ų113156.4 Ų156.479%0.7982%0.824SS**  trans-56.3131.2173.649.70000115.2
649S28.8Very low27.4Very low123 Ų123156.1 Ų156.186%0.8683%0.825SS**  trans-142.858.2146.3720000110.3
650S28.4Very low27.8Very low101 Ų101156.6 Ų156.671%0.70683%0.826SS**  trans-105.490.6162.857.40000107.2P652S650-P652 VanDerWaalsContact O-CD 3.27Å; S650-P652 WeakPolarHBondContact O-CD 3.1Å
651S29.8Very low27.8Very low115 Ų115150.3 Ų150.380%0.80481%0.814SS**  trans-62.2117.2165.537.80000107.8L653S651-L653 PolarHBondContact O-N 2.88Å
652P30.2Very low27.8Very low117 Ų117153.1 Ų153.176%0.7682%0.819SS**  trans-67.5133.7175.7-11.827.1000108.4S650 Q654S650-P652 VanDerWaalsContact O-CD 3.27Å; S650-P652 WeakPolarHBondContact O-CD 3.1Å; P652-Q654 PolarHBondContact O-N 2.95Å
653L28.8Very low28.2Very low178 Ų178153.1 Ų153.193%0.93282%0.819SS**  trans-37.8100170.6-73.7153.6000110.7S651 R655S651-L653 PolarHBondContact O-N 2.88Å; L653-R655 PolarHBondContact O-N 2.97Å
654Q29Very low28.4Very low184 Ų184149.6 Ų149.686%0.8681%0.814SS**  trans-70.7106.1174-144.2169.98.700106.1P652 M656P652-Q654 PolarHBondContact O-N 2.95Å; Q654-M656 PolarHBondContact O-N 3.4Å
655R27.4Very low28.7Very low214 Ų214153.3 Ų153.381%0.80882%0.819SS**  trans-40.1112.6171.8-167.3177.4-161.6168.63.7108.4L653 H657L653-R655 PolarHBondContact O-N 2.97Å; R655-H657 VanDerWaalsContact C-N 3.33Å; R655-H657 PolarHBondContact O-N 2.78Å
656M28.6Very low28.8Very low181 Ų181152.4 Ų152.489%0.89282%0.816SS**  trans-59.394.1-178.5-70.6175.366.100109.2Q654 L658Q654-M656 PolarHBondContact O-N 3.4Å; M656-L658 PolarHBondContact O-N 3.02Å
657H30.8Very low29.3Very low164 Ų164154.3 Ų154.376%0.75982%0.816SS**  trans-73113.3165-85.4-72.9000107.1R655 M659R655-H657 VanDerWaalsContact C-N 3.33Å; R655-H657 PolarHBondContact O-N 2.78Å; H657-M659 PolarHBondContact O-N 2.98Å; H657-M659 VanDerWaalsContact O-N 3.12Å
658L31.2Very low29.3Very low146 Ų146155 Ų15576%0.76482%0.818SS**  trans-45.3118.4166-72.2160.4000108.1M656 P660M656-L658 PolarHBondContact O-N 3.02Å; L658-P660 WeakPolarHBondContact O-CD 3.27Å
659M27.7Very low29.7Very low183 Ų183152.3 Ų152.390%0.90181%0.809SS**PPolyproline II helixtrans-62.2124.6179.6-70.7-172.481.600109H657H657-M659 PolarHBondContact O-N 2.98Å; H657-M659 VanDerWaalsContact O-N 3.12Å
660P29.7Very low29.9Very low111 Ų111153.2 Ų153.272%0.72180%0.803SS**PPolyproline II helixtrans-67.7151169.626.3-30.5000110.2L658L658-P660 WeakPolarHBondContact O-CD 3.27Å
661P29Very low30.5Very low102 Ų102153.7 Ų153.766%0.66280%0.804SS**PPolyproline II helixtrans-60.3154.2-175.323.9-32.8000112.3R663P661-R663 PolarHBondContact O-N 2.99Å
662P26.1Very low30.7Very low128 Ų128156 Ų15683%0.83180%0.802SS**PPolyproline II helixtrans-59.2130-172.521.4-31.3000111.6
663R31.5Very low30.9Very low236 Ų236158.8 Ų158.889%0.89181%0.81SS**PPolyproline II helixtrans-60.5139.4174.5-80.5-176.1-177.5-171.40.4110.1P661 K665P661-R663 PolarHBondContact O-N 2.99Å; R663-K665 PolarHBondContact O-N 3.06Å
664P29Very low31Very low123 Ų123154.5 Ų154.580%0.79980%0.8SS**PPolyproline II helixtrans-55.1135.8173.3-21.130.4000110.8R666P664-R666 PolarHBondContact O-N 2.55Å
665K30.2Very low31Very low204 Ų204153.7 Ų153.789%0.88780%0.8SS**PPolyproline II helixtrans-54.7116.5174.3-71.5-177.5179179.10108.3R663 I667R663-K665 PolarHBondContact O-N 3.06Å; K665-I667 PolarHBondContact O-N 3.24Å
666R28.5Very low31.4Very low232 Ų232153.4 Ų153.488%0.87583%0.829SS**  trans-58.2110.2170.8-123.1179.8-178.9-179.1-1.1106.7P664 T668P664-R666 PolarHBondContact O-N 2.55Å; R666-T668 VanDerWaalsContact C-N 3.33Å; R666-T668 PolarHBondContact O-N 3.1Å
667I33.5Very low31.5Very low164 Ų164152.1 Ų152.184%0.84183%0.826SS**  trans-63.6101.9166.9-63.2172.6000105.2K665 G669K665-I667 PolarHBondContact O-N 3.24Å; I667-G669 PolarHBondContact O-N 3.34Å
668T32.4Very low31.6Very low135 Ų135151.4 Ų151.483%0.82883%0.829SS**  trans-74.674.7168.850.20000107.6R666R666-T668 VanDerWaalsContact C-N 3.33Å; R666-T668 PolarHBondContact O-N 3.1Å
669G33.7Very low31.6Very low58 Ų58151.7 Ų151.760%0.59883%0.833SS**  trans-81.3111.2166.200000108.4I667I667-G669 PolarHBondContact O-N 3.34Å
670N33.3Very low31.8Very low141 Ų141149.9 Ų149.975%0.75483%0.829SS**  trans-59.1123.3-180-1633.4000110.7H672N670-H672 VanDerWaalsContact C-N 3.3Å; N670-H672 PolarHBondContact O-N 3.32Å
671P41.1Very low31.9Very low111 Ų111152.3 Ų152.372%0.72184%0.836SS**SBendtrans-84.571.9-17734.1-33.1000110.5
672H32.7Very low32.1Very low164 Ų164155.7 Ų155.776%0.75985%0.847SS**  trans-153.983.8164.3-87-66.5000109.8N670N670-H672 VanDerWaalsContact C-N 3.3Å; N670-H672 PolarHBondContact O-N 3.32Å
673L35.3Very low32.6Very low176 Ų176157.6 Ų157.692%0.92185%0.849SS**  trans-161.372.8150.3-103143.4000107.4
674A30.4Very low32.7Very low87 Ų87151.6 Ų151.672%0.71985%0.845SS**  trans-88.3144.8151.100000107.4
675L29.9Very low33Very low167 Ų167154 Ų15487%0.87485%0.849SS**  trans88.986.6169.8-56.4158.8000116.8
676C34.8Very low33.2Very low209 Ų209149.5 Ų149.5100%1.41285%0.846SS**  -163.70109.1-96.70000109

Retrieved 676 of 676 residues in 372.2 ms (Link to these results)