A0A077Z381_TRITR Loading...

Peptidase C1 domain containing protein

AlphaFold DB , UniProt , Accession A0A077Z381, Species TRITR (Trichuris trichiura, Whipworm), Gene n/a, Length 1,051 aa.

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Site Residue pLDDT pLDDT confidence pLDDT10 pLDDT10 confidence SASA SASA [Ų] SASA10 SASA10 [Ų] RSA RSA unformatted RSA10 RSA10 unformatted Surface Surface10 (not used) Disorder (not used) Disorder Sec. str. Secondary structure Isomer Phi (φ) Psi (ψ) Omega (ω) Chi 1 (χ1) Chi 2 (χ2) Chi 3 (χ3) Chi 4 (χ4) Chi 5 (χ5) Tau (τ) Contacts (colored by PAE) Contact details
1M50.3Low54.9Low219 Ų219131.3 Ų131.3100%1.07965%0.647SS**  0-39.40-89.7173.5136.200113.9F3 W4M1-F3 VanDerWaalsContact C-N 3.33Å; M1-F3 PolarHBondContact O-N 2.79Å; M1-W4 PolarHBondContact O-N 2.92Å
2H57Low54.4Low168 Ų168124.7 Ų124.778%0.77863%0.629SS**Hα-helixtrans-63.7-27.4-179.1-72.8-44.2000116.1W4H2-W4 PolarHBondContact O-N 2.91Å
3F56.8Low54Low177 Ų177120.7 Ų120.778%0.77662%0.615SS**Hα-helixtrans-66.9-32.9176.8-115-91.5000113.7M1 C7M1-F3 VanDerWaalsContact C-N 3.33Å; M1-F3 PolarHBondContact O-N 2.79Å; F3-C7 PolarHBondContact O-N 3.11Å
4W52.7Low53.4Low196 Ų196116.1 Ų116.174%0.74261%0.605SS**Hα-helixtrans-78.2-32.8-178.3-79.550.7000112.2M1 H2 L6 C7 F8M1-W4 PolarHBondContact O-N 2.92Å; H2-W4 PolarHBondContact O-N 2.91Å; W4-L6 VanDerWaalsContact C-N 3.31Å; W4-L6 PolarHBondContact O-N 3.26Å; W4-C7 PolarHBondContact O-N 3.13Å; W4-F8 HydrophobicContact CE3-CE2 4.36Å; W4-F8 WeakPolarHBondContact O-CD2 3.4Å; W4-F8 PolarHBondContact O-N 3.48Å
5S60.7Low52.9Low71 Ų71120.5 Ų120.550%0.49761%0.612SS.*Hα-helixtrans-67.8-31.4176.9-162.60000112.5L9S5-L9 PolarHBondContact O-N 3.13Å
6L56.1Low52.6Low120 Ų120119.4 Ų119.463%0.62861%0.613SS**Hα-helixtrans-73.1-39.8175.8-90.5146.2000112W4 L9 T10W4-L6 VanDerWaalsContact C-N 3.31Å; W4-L6 PolarHBondContact O-N 3.26Å; L6-L9 PolarHBondContact O-N 3.36Å; L6-T10 WeakPolarHBondContact O-CG2 3.32Å; L6-T10 PolarHBondContact O-N 3.12Å; L6-T10 PolarHBondContact O-OG1 3.42Å
7C56.7Low52.2Low67 Ų67120.4 Ų120.445%0.45362%0.619SS.*Hα-helixtrans-65.6-38.4173.8-84.30000113F3 W4 T10 I11F3-C7 PolarHBondContact O-N 3.11Å; W4-C7 PolarHBondContact O-N 3.13Å; C7-T10 WeakPolarHBondContact CA-OG1 3.24Å; C7-T10 PolarHBondContact O-N 3.35Å; C7-T10 PolarHBondContact O-OG1 2.68Å; C7-I11 WeakPolarHBondContact O-CB 3.37Å; C7-I11 WeakPolarHBondContact O-CD1 3.39Å; C7-I11 WeakPolarHBondContact O-CG1 3.26Å; C7-I11 PolarHBondContact O-N 2.69Å
8F54.3Low52.1Low144 Ų144117.9 Ų117.963%0.63262%0.62SS**Hα-helixtrans-68.6-36.4176.3-93.7-82000112.4W4 A12W4-F8 HydrophobicContact CE3-CE2 4.36Å; W4-F8 WeakPolarHBondContact O-CD2 3.4Å; W4-F8 PolarHBondContact O-N 3.48Å; F8-A12 WeakPolarHBondContact O-CB 3.39Å; F8-A12 PolarHBondContact O-N 3.05Å
9L53.7Low52.4Low111 Ų111116.6 Ų116.658%0.58161%0.612SS**Hα-helixtrans-67.5-40.7173.4-106.4123.3000112S5 L6 A12 T13S5-L9 PolarHBondContact O-N 3.13Å; L6-L9 PolarHBondContact O-N 3.36Å; L9-A12 PolarHBondContact O-N 2.57Å; L9-T13 WeakPolarHBondContact O-CB 3.46Å; L9-T13 WeakPolarHBondContact O-CG2 3.36Å; L9-T13 PolarHBondContact O-N 3.12Å; L9-T13 PolarHBondContact O-OG1 2.85Å
10T52.9Low53.3Low78 Ų78112.1 Ų112.148%0.47959%0.591SS.*Hα-helixtrans-68.5-40.5177.553.90000112.5L6 C7 T13 A14L6-T10 WeakPolarHBondContact O-CG2 3.32Å; L6-T10 PolarHBondContact O-N 3.12Å; L6-T10 PolarHBondContact O-OG1 3.42Å; C7-T10 WeakPolarHBondContact CA-OG1 3.24Å; C7-T10 PolarHBondContact O-N 3.35Å; C7-T10 PolarHBondContact O-OG1 2.68Å; T10-T13 VanDerWaalsContact CA-OG1 3.32Å; T10-T13 WeakPolarHBondContact CA-OG1 3.25Å; T10-T13 PolarHBondContact O-N 3.28Å; T10-T13 PolarHBondContact O-OG1 3.26Å; T10-A14 VanDerWaalsContact O-CB 3.27Å; T10-A14 WeakPolarHBondContact O-CB 3.47Å; T10-A14 PolarHBondContact O-N 2.89Å
11I52.4Low54.7Low93 Ų93109.8 Ų109.848%0.47758%0.576SS.*Hα-helixtrans-67.8-39.9175.8-64.8165.7000110.9C7 A14 Y15C7-I11 WeakPolarHBondContact O-CB 3.37Å; C7-I11 WeakPolarHBondContact O-CD1 3.39Å; C7-I11 WeakPolarHBondContact O-CG1 3.26Å; C7-I11 PolarHBondContact O-N 2.69Å; I11-A14 PolarHBondContact O-N 2.96Å; I11-Y15 HydrophobicContact CG2-CD2 3.91Å; I11-Y15 HydrophobicContact CG2-CE2 4.25Å; I11-Y15 WeakPolarHBondContact O-CB 3.14Å; I11-Y15 PolarHBondContact O-N 3.07Å
12A49.6Very low56.3Low52 Ų5299.4 Ų99.443%0.4353%0.525SS..Hα-helixtrans-66.2-41.4174.700000111.8F8 L9 A14 Y15 V16F8-A12 WeakPolarHBondContact O-CB 3.39Å; F8-A12 PolarHBondContact O-N 3.05Å; L9-A12 PolarHBondContact O-N 2.57Å; A12-A14 VanDerWaalsContact C-N 3.33Å; A12-A14 PolarHBondContact O-N 3.09Å; A12-Y15 PolarHBondContact O-N 2.75Å; A12-V16 WeakPolarHBondContact O-CB 3.24Å; A12-V16 VanDerWaalsContact O-CG2 3.22Å; A12-V16 WeakPolarHBondContact O-CG2 3.39Å; A12-V16 PolarHBondContact O-N 3.02Å
13T48.2Very low57.8Low73 Ų7393.1 Ų93.145%0.44850%0.496SS..Hα-helixtrans-66.9-32.9172.952.20000112.4L9 T10 N17L9-T13 WeakPolarHBondContact O-CB 3.46Å; L9-T13 WeakPolarHBondContact O-CG2 3.36Å; L9-T13 PolarHBondContact O-N 3.12Å; L9-T13 PolarHBondContact O-OG1 2.85Å; T10-T13 VanDerWaalsContact CA-OG1 3.32Å; T10-T13 WeakPolarHBondContact CA-OG1 3.25Å; T10-T13 PolarHBondContact O-N 3.28Å; T10-T13 PolarHBondContact O-OG1 3.26Å; T13-N17 WeakPolarHBondContact O-CB 3.31Å; T13-N17 PolarHBondContact O-N 3.28Å; T13-N17 PolarHBondContact O-ND2 2.91Å; T13-N17 VanDerWaalsContact O-ND2 3.13Å
14A46Very low59.2Low57 Ų5791.2 Ų91.247%0.47149%0.487SS..Hα-helixtrans-71-37.9175.500000112.2T10 I11 A12 N17 A18T10-A14 VanDerWaalsContact O-CB 3.27Å; T10-A14 WeakPolarHBondContact O-CB 3.47Å; T10-A14 PolarHBondContact O-N 2.89Å; I11-A14 PolarHBondContact O-N 2.96Å; A12-A14 VanDerWaalsContact C-N 3.33Å; A12-A14 PolarHBondContact O-N 3.09Å; A14-N17 PolarHBondContact O-N 3.23Å; A14-A18 WeakPolarHBondContact O-CB 3.33Å; A14-A18 PolarHBondContact O-N 3.37Å; A14-A18 VanDerWaalsContact O-N 3.09Å
15Y46.1Very low60.8Low181 Ų18183.2 Ų83.271%0.7146%0.458SS*.Hα-helixtrans-71.7-37.9174.8-100-87.7000112.6I11 A12 N17 A18I11-Y15 HydrophobicContact CG2-CD2 3.91Å; I11-Y15 HydrophobicContact CG2-CE2 4.25Å; I11-Y15 WeakPolarHBondContact O-CB 3.14Å; I11-Y15 PolarHBondContact O-N 3.07Å; A12-Y15 PolarHBondContact O-N 2.75Å; Y15-N17 VanDerWaalsContact C-N 3.32Å; Y15-A18 PolarHBondContact O-N 2.78Å
16V47.6Very low62.1Low103 Ų10381 Ų8162%0.62444%0.44SS*.Hα-helixtrans-70.7-30.1174.4176.50000111.2A12 A18A12-V16 WeakPolarHBondContact O-CB 3.24Å; A12-V16 VanDerWaalsContact O-CG2 3.22Å; A12-V16 WeakPolarHBondContact O-CG2 3.39Å; A12-V16 PolarHBondContact O-N 3.02Å; V16-A18 VanDerWaalsContact C-N 3.33Å
17N47.3Very low63.6Low136 Ų13680.4 Ų80.473%0.72743%0.434SS*.THydrogen-bonded Turntrans-80.5-6.7172.3-72.2-22.4000114.3T13 A14 Y15T13-N17 WeakPolarHBondContact O-CB 3.31Å; T13-N17 PolarHBondContact O-N 3.28Å; T13-N17 PolarHBondContact O-ND2 2.91Å; T13-N17 VanDerWaalsContact O-ND2 3.13Å; A14-N17 PolarHBondContact O-N 3.23Å; Y15-N17 VanDerWaalsContact C-N 3.32Å
18A49.1Very low64.9Low76 Ų7682.5 Ų82.563%0.62844%0.437SS*.THydrogen-bonded Turntrans-94.4-0.8178.300000113.8A14 Y15 V16 S20A14-A18 WeakPolarHBondContact O-CB 3.33Å; A14-A18 PolarHBondContact O-N 3.37Å; A14-A18 VanDerWaalsContact O-N 3.09Å; Y15-A18 PolarHBondContact O-N 2.78Å; V16-A18 VanDerWaalsContact C-N 3.33Å; A18-S20 PolarHBondContact O-N 3.39Å
19I58.3Low66.2Low93 Ų9376.6 Ų76.648%0.47741%0.412SS..SBendtrans-77.7113.8173.3-56.4176.5000107.7E23 K24I19-E23 HydrophobicContact CG2-CB 3.73Å; I19-K24 HydrophobicContact CG2-CB 4.07Å
20S70.7Confident67.7Low26 Ų2676 Ų7618%0.18240%0.404CS..  trans-60.9157.8175.327.80000112.1A18 Y22 E23 K24 G56A18-S20 PolarHBondContact O-N 3.39Å; S20-Y22 PolarHBondContact O-N 3.05Å; S20-Y22 VanDerWaalsContact O-N 3.16Å; S20-E23 VanDerWaalsContact CB-OE2 3.31Å; S20-E23 WeakPolarHBondContact CB-OE2 3.46Å; S20-E23 PolarHBondContact O-N 3.29Å; S20-E23 PolarHBondContact OG-OE1 3.45Å; S20-E23 PolarHBondContact OG-OE2 2.91Å; S20-K24 PolarHBondContact O-N 3.01Å; S20-G56 WeakPolarHBondContact OG-CA 3.35Å; S20-G56 PolarHBondContact OG-N 3.49Å
21F81.8Confident69.2Low65 Ų6575 Ų7529%0.28540%0.401SS..Hα-helixtrans-48.1-44.1-178.3165.6-98.3000112.7K24 H25 L59 I62 M268F21-K24 PolarHBondContact O-N 3.11Å; F21-H25 HydrophobicContact CE2-CB 4.32Å; F21-H25 HydrophobicContact CZ-CB 4.26Å; F21-H25 WeakPolarHBondContact O-CB 3.31Å; F21-H25 PolarHBondContact O-N 3.04Å; F21-L59 HydrophobicContact CD1-CB 3.69Å; F21-L59 HydrophobicContact CD1-CD1 4.44Å; F21-L59 HydrophobicContact CD2-CB 4.16Å; F21-L59 HydrophobicContact CE1-CB 3.74Å; F21-L59 HydrophobicContact CE1-CD1 3.66Å; F21-L59 HydrophobicContact CE1-CG 4.18Å; F21-L59 HydrophobicContact CE2-CB 4.21Å; F21-L59 HydrophobicContact CE2-CD2 4.28Å; F21-L59 HydrophobicContact CG-CB 3.92Å; F21-L59 HydrophobicContact CZ-CB 4.01Å; F21-L59 HydrophobicContact CZ-CD1 3.8Å; F21-L59 HydrophobicContact CZ-CD2 4.15Å; F21-L59 HydrophobicContact CZ-CG 4.2Å; F21-I62 HydrophobicContact CD1-CD1 4.35Å; F21-M268 HydrophobicContact CE1-CE 4.22Å
22Y84.9Confident70.5Confident0 Ų073.7 Ų73.70%040%0.4CS..Hα-helixtrans-60.4-49.9-176.5-179.2-111.3000113.4S20 H25 F26 L50 N51 F54 M55 I62 M268 Y269S20-Y22 PolarHBondContact O-N 3.05Å; S20-Y22 VanDerWaalsContact O-N 3.16Å; Y22-H25 PolarHBondContact O-N 3.36Å; Y22-F26 PolarHBondContact O-N 2.94Å; Y22-L50 HydrophobicContact CD1-CD2 4Å; Y22-L50 HydrophobicContact CE1-CB 4.36Å; Y22-L50 HydrophobicContact CE1-CD2 3.57Å; Y22-N51 WeakPolarHBondContact OH-CB 3.42Å; Y22-N51 PolarHBondContact OH-N 2.9Å; Y22-F54 HydrophobicContact CD1-CB 3.75Å; Y22-F54 WeakPolarHBondContact CD1-O 3.28Å; Y22-F54 HydrophobicContact CD2-CB 3.69Å; Y22-F54 HydrophobicContact CD2-CG 4.44Å; Y22-F54 HydrophobicContact CE1-CB 3.66Å; Y22-F54 HydrophobicContact CE2-CB 3.6Å; Y22-F54 HydrophobicContact CE2-CD2 4.07Å; Y22-F54 HydrophobicContact CE2-CG 4.1Å; Y22-F54 HydrophobicContact CG-CB 3.77Å; Y22-M55 HydrophobicContact CD1-SD 4.23Å; Y22-M55 HydrophobicContact CE1-SD 4.12Å; Y22-I62 HydrophobicContact CD2-CD1 4.49Å; Y22-M268 HydrophobicContact CD2-CB 4.37Å; Y22-M268 HydrophobicContact CD2-CE 4.4Å; Y22-M268 HydrophobicContact CE2-CB 3.71Å; Y22-M268 PolarHBondContact OH-O 3.25Å; Y22-Y269 HydrophobicContact CD2-CD1 4.4Å; Y22-Y269 AromaticContact CD2-CE1 3.53Å; Y22-Y269 HydrophobicContact CD2-CE1 3.53Å; Y22-Y269 AromaticContact CD2-CZ 3.75Å; Y22-Y269 WeakPolarHBondContact CD2-OH 3.13Å; Y22-Y269 HydrophobicContact CE1-CE1 4.19Å; Y22-Y269 AromaticContact CE2-CD1 3.52Å; Y22-Y269 HydrophobicContact CE2-CD1 3.52Å; Y22-Y269 AromaticContact CE2-CE1 3.07Å; Y22-Y269 HydrophobicContact CE2-CE1 3.07Å; Y22-Y269 HydrophobicContact CE2-CE2 4.44Å; Y22-Y269 HydrophobicContact CE2-CG 4.39Å; Y22-Y269 AromaticContact CE2-CZ 3.6Å; Y22-Y269 HydrophobicContact CG-CE1 4.24Å; Y22-Y269 AromaticContact CZ-CD1 3.58Å; Y22-Y269 AromaticContact CZ-CE1 3.45Å; Y22-Y269 VanDerWaalsContact CZ-CE1 3.45Å; Y22-Y269 PolarHBondContact O-OH 3.14Å; Y22-Y269 WeakPolarHBondContact OH-CD1 3.34Å
23E87.9Confident71.8Confident37 Ų3772.3 Ų72.317%0.17339%0.385CS..Hα-helixtrans-68.7-37.4-178.7-66.887.9154.400111.6I19 S20 F26 L50 M55 G56I19-E23 HydrophobicContact CG2-CB 3.73Å; S20-E23 VanDerWaalsContact CB-OE2 3.31Å; S20-E23 WeakPolarHBondContact CB-OE2 3.46Å; S20-E23 PolarHBondContact O-N 3.29Å; S20-E23 PolarHBondContact OG-OE1 3.45Å; S20-E23 PolarHBondContact OG-OE2 2.91Å; E23-F26 WeakPolarHBondContact O-CB 3.21Å; E23-L50 HydrophobicContact CG-CD2 4.49Å; E23-M55 HydrophobicContact CG-CE 3.7Å; E23-M55 HydrophobicContact CG-SD 4Å; E23-M55 WeakPolarHBondContact OE1-CA 3.25Å; E23-M55 VanDerWaalsContact OE1-CE 3.26Å; E23-M55 WeakPolarHBondContact OE1-CE 3.36Å; E23-G56 PolarHBondContact OE1-N 2.74Å
24K85.4Confident73.1Confident136 Ų13670.3 Ų70.359%0.59138%0.379SS*.Hα-helixtrans-66.9-45.1175.9-174.6179.4175.6-176.70111.5I19 S20 F21 F26 E27I19-K24 HydrophobicContact CG2-CB 4.07Å; S20-K24 PolarHBondContact O-N 3.01Å; F21-K24 PolarHBondContact O-N 3.11Å; K24-F26 VanDerWaalsContact C-N 3.26Å; K24-F26 PolarHBondContact O-N 3.16Å; K24-E27 PolarHBondContact O-N 3.09Å
25H87.1Confident74.6Confident29 Ų2973.9 Ų73.913%0.13438%0.384CS..Hα-helixtrans-67.7-26.2-179.4-167.282.5000112.2F21 Y22 E27 E28 I29 S265 Y269F21-H25 HydrophobicContact CE2-CB 4.32Å; F21-H25 HydrophobicContact CZ-CB 4.26Å; F21-H25 WeakPolarHBondContact O-CB 3.31Å; F21-H25 PolarHBondContact O-N 3.04Å; Y22-H25 PolarHBondContact O-N 3.36Å; H25-E27 VanDerWaalsContact C-N 3.32Å; H25-E27 PolarHBondContact O-N 3.25Å; H25-E28 IonicContact ND1-OE2 3.26Å; H25-E28 WeakPolarHBondContact O-CB 3.26Å; H25-E28 PolarHBondContact O-N 3.09Å; H25-I29 WeakPolarHBondContact O-CG1 3.42Å; H25-I29 PolarHBondContact O-N 2.99Å; H25-S265 WeakPolarHBondContact NE2-CB 3.28Å; H25-S265 PolarHBondContact NE2-OG 2.83Å; H25-Y269 WeakPolarHBondContact CB-OH 3.37Å; H25-Y269 AromaticContact CD2-CE2 3.85Å; H25-Y269 PolarHBondContact CD2-OH 3.17Å
26F88.4Confident75.7Confident25 Ų2567.7 Ų67.711%0.1136%0.362CS..Hα-helixtrans-58.1-41173.1-178.4-114.9000113.2Y22 E23 K24 E28 I29 K30 Y48 L50 Y269Y22-F26 PolarHBondContact O-N 2.94Å; E23-F26 WeakPolarHBondContact O-CB 3.21Å; K24-F26 VanDerWaalsContact C-N 3.26Å; K24-F26 PolarHBondContact O-N 3.16Å; F26-E28 VanDerWaalsContact C-N 3.31Å; F26-E28 PolarHBondContact O-N 2.96Å; F26-I29 PolarHBondContact O-N 3.49Å; F26-K30 HydrophobicContact CE1-CD 4.38Å; F26-K30 VanDerWaalsContact O-CB 3.28Å; F26-K30 WeakPolarHBondContact O-CB 3.44Å; F26-K30 PolarHBondContact O-N 2.93Å; F26-Y48 AromaticContact CE2-CD2 3.85Å; F26-Y48 HydrophobicContact CE2-CD2 3.85Å; F26-Y48 HydrophobicContact CE2-CE2 4.37Å; F26-Y48 HydrophobicContact CZ-CD2 4.34Å; F26-L50 HydrophobicContact CB-CD2 3.61Å; F26-L50 HydrophobicContact CB-CG 4.47Å; F26-L50 HydrophobicContact CD1-CD1 4.29Å; F26-L50 HydrophobicContact CD1-CD2 3.96Å; F26-L50 HydrophobicContact CD1-CG 3.88Å; F26-L50 HydrophobicContact CD2-CD2 4.1Å; F26-L50 HydrophobicContact CD2-CG 4.37Å; F26-L50 HydrophobicContact CE1-CG 4.16Å; F26-L50 HydrophobicContact CG-CD2 3.62Å; F26-L50 HydrophobicContact CG-CG 3.99Å; F26-Y269 HydrophobicContact CB-CD1 4.14Å; F26-Y269 HydrophobicContact CB-CE1 3.63Å; F26-Y269 AromaticContact CD2-CD1 3.37Å; F26-Y269 HydrophobicContact CD2-CD1 3.37Å; F26-Y269 AromaticContact CD2-CE1 3.8Å; F26-Y269 HydrophobicContact CD2-CE1 3.8Å; F26-Y269 AromaticContact CD2-CG 3.92Å; F26-Y269 HydrophobicContact CD2-CG 3.92Å; F26-Y269 HydrophobicContact CE2-CD1 4.17Å; F26-Y269 HydrophobicContact CG-CD1 4.16Å; F26-Y269 HydrophobicContact CG-CE1 4.16Å
27E86.5Confident76.6Confident107 Ų10769.1 Ų69.150%0.536%0.359SS..Hα-helixtrans-67.8-32.9178.1-68.5-59146.600111.8K24 H25 K30 S31K24-E27 PolarHBondContact O-N 3.09Å; H25-E27 VanDerWaalsContact C-N 3.32Å; H25-E27 PolarHBondContact O-N 3.25Å; E27-K30 IonicContact OE1-NZ 3.62Å; E27-K30 IonicContact OE2-NZ 3.43Å; E27-S31 WeakPolarHBondContact O-CB 3.31Å; E27-S31 PolarHBondContact O-N 3.09Å
28E84.4Confident77.4Confident110 Ų11070 Ų7051%0.51436%0.363SS..Hα-helixtrans-66.1-46173.3-61.3-179-169.600111.5H25 F26 S31 S32H25-E28 IonicContact ND1-OE2 3.26Å; H25-E28 WeakPolarHBondContact O-CB 3.26Å; H25-E28 PolarHBondContact O-N 3.09Å; F26-E28 VanDerWaalsContact C-N 3.31Å; F26-E28 PolarHBondContact O-N 2.96Å; E28-S31 WeakPolarHBondContact O-CB 2.97Å; E28-S31 PolarHBondContact O-N 3.04Å; E28-S32 WeakPolarHBondContact O-CB 3.29Å; E28-S32 PolarHBondContact O-N 2.84Å
29I83.1Confident78.2Confident21 Ų2174.6 Ų74.611%0.10837%0.369CS..Hα-helixtrans-61.9-46.7175.9-67.9-62.4000111.2H25 F26 S31 S32 L33 D266 Y269H25-I29 WeakPolarHBondContact O-CG1 3.42Å; H25-I29 PolarHBondContact O-N 2.99Å; F26-I29 PolarHBondContact O-N 3.49Å; I29-S31 VanDerWaalsContact C-N 3.28Å; I29-S31 PolarHBondContact O-N 2.95Å; I29-S32 PolarHBondContact O-N 3.13Å; I29-S32 VanDerWaalsContact O-N 3.17Å; I29-L33 HydrophobicContact CG2-CD1 3.7Å; I29-L33 HydrophobicContact CG2-CG 4.19Å; I29-L33 WeakPolarHBondContact O-CB 3.48Å; I29-L33 WeakPolarHBondContact O-CG 3.41Å; I29-L33 PolarHBondContact O-N 2.92Å; I29-D266 HydrophobicContact CD1-CB 4.06Å; I29-Y269 HydrophobicContact CG1-CD2 4.13Å; I29-Y269 HydrophobicContact CG1-CE2 3.83Å; I29-Y269 HydrophobicContact CG2-CD2 4.36Å
30K84.9Confident78.5Confident97 Ų9776.4 Ų76.442%0.42238%0.375SS..Hα-helixtrans-59.2-40.2177.6-176.3-179.7171.1-165.50111.7F26 E27 G34 Y48F26-K30 HydrophobicContact CE1-CD 4.38Å; F26-K30 VanDerWaalsContact O-CB 3.28Å; F26-K30 WeakPolarHBondContact O-CB 3.44Å; F26-K30 PolarHBondContact O-N 2.93Å; E27-K30 IonicContact OE1-NZ 3.62Å; E27-K30 IonicContact OE2-NZ 3.43Å; K30-G34 PolarHBondContact O-N 3.07Å; K30-Y48 HydrophobicContact CB-CE2 4.29Å; K30-Y48 HydrophobicContact CG-CE2 4.37Å
31S83.5Confident77.9Confident59 Ų5978.4 Ų78.441%0.41340%0.4SS..Hα-helixtrans-65.7-45.6173.8-172.80000112.3E27 E28 I29 G34 K35E27-S31 WeakPolarHBondContact O-CB 3.31Å; E27-S31 PolarHBondContact O-N 3.09Å; E28-S31 WeakPolarHBondContact O-CB 2.97Å; E28-S31 PolarHBondContact O-N 3.04Å; I29-S31 VanDerWaalsContact C-N 3.28Å; I29-S31 PolarHBondContact O-N 2.95Å; S31-G34 PolarHBondContact O-N 2.94Å; S31-K35 WeakPolarHBondContact O-CG 3.18Å; S31-K35 PolarHBondContact O-N 3.42Å
32S80.1Confident76.8Confident65 Ų6580 Ų8046%0.45542%0.415SS..Hα-helixtrans-62.2-48.5179-169.70000112.3E28 I29 G34 K35 E36E28-S32 WeakPolarHBondContact O-CB 3.29Å; E28-S32 PolarHBondContact O-N 2.84Å; I29-S32 PolarHBondContact O-N 3.13Å; I29-S32 VanDerWaalsContact O-N 3.17Å; S32-G34 VanDerWaalsContact C-N 3.33Å; S32-G34 PolarHBondContact O-N 2.78Å; S32-K35 WeakPolarHBondContact O-CB 3.42Å; S32-K35 PolarHBondContact O-N 2.94Å; S32-E36 PolarHBondContact O-N 2.97Å
33L76.5Confident76.1Confident23 Ų2384.1 Ų84.112%0.1244%0.444CS..Hα-helixtrans-65.6-35177-68.4177000112.3I29 E36 K37 V44 W46 Y48I29-L33 HydrophobicContact CG2-CD1 3.7Å; I29-L33 HydrophobicContact CG2-CG 4.19Å; I29-L33 WeakPolarHBondContact O-CB 3.48Å; I29-L33 WeakPolarHBondContact O-CG 3.41Å; I29-L33 PolarHBondContact O-N 2.92Å; L33-E36 PolarHBondContact O-N 3.33Å; L33-K37 PolarHBondContact O-N 3.37Å; L33-V44 HydrophobicContact CD2-CG1 3.78Å; L33-W46 HydrophobicContact CD1-CH2 4.47Å; L33-W46 HydrophobicContact CD1-CZ2 4.33Å; L33-Y48 HydrophobicContact CB-CE1 4.41Å; L33-Y48 HydrophobicContact CD1-CD1 3.66Å; L33-Y48 HydrophobicContact CD1-CD2 4.1Å; L33-Y48 HydrophobicContact CD1-CE1 3.55Å; L33-Y48 HydrophobicContact CD1-CE2 4.02Å; L33-Y48 HydrophobicContact CD1-CG 3.95Å
34G76.4Confident75.4Confident31 Ų3184 Ų8432%0.3245%0.446SS..Hα-helixtrans-61.1-43.9171.400000112.5K30 S31 S32 K37 L38K30-G34 PolarHBondContact O-N 3.07Å; S31-G34 PolarHBondContact O-N 2.94Å; S32-G34 VanDerWaalsContact C-N 3.33Å; S32-G34 PolarHBondContact O-N 2.78Å; G34-K37 PolarHBondContact O-N 3.37Å; G34-L38 WeakPolarHBondContact O-CG 3.16Å; G34-L38 PolarHBondContact O-N 3.48Å
35K76Confident75Confident131 Ų13181.4 Ų81.457%0.5744%0.443SS*.Hα-helixtrans-65.4-39.1175.8-71.7170.1-177.4173.40112.4S31 S32 L38 K39S31-K35 WeakPolarHBondContact O-CG 3.18Å; S31-K35 PolarHBondContact O-N 3.42Å; S32-K35 WeakPolarHBondContact O-CB 3.42Å; S32-K35 PolarHBondContact O-N 2.94Å; K35-L38 PolarHBondContact O-N 2.67Å; K35-K39 PolarHBondContact O-N 2.84Å
36E68.8Low74.8Confident52 Ų5281 Ų8124%0.24344%0.44CS..Hα-helixtrans-63.6-43.4175.1-75.4-155.8147.900112.4S32 L33 L38 K39 H40 R278S32-E36 PolarHBondContact O-N 2.97Å; L33-E36 PolarHBondContact O-N 3.33Å; E36-L38 PolarHBondContact O-N 2.71Å; E36-K39 PolarHBondContact O-N 2.85Å; E36-K39 VanDerWaalsContact O-N 3.11Å; E36-H40 PolarHBondContact O-N 2.81Å; E36-R278 IonicContact OE1-CZ 3.88Å; E36-R278 IonicContact OE1-NH1 2.88Å; E36-R278 PolarHBondContact OE1-NH1 3.3Å; E36-R278 IonicContact OE1-NH2 2.67Å; E36-R278 PolarHBondContact OE1-NH2 3.26Å; E36-R278 IonicContact OE2-CZ 3.17Å; E36-R278 IonicContact OE2-NH1 3.03Å; E36-R278 IonicContact OE2-NH2 3.89Å; E36-R278 PolarHBondContact OE2-NH2 2.92Å
37K68.3Low74.7Confident133 Ų13385.6 Ų85.658%0.57846%0.46SS*.Hα-helixtrans-58.5-37.6175.8-174.3177.2177.8-178.50111.7L33 G34 G41L33-K37 PolarHBondContact O-N 3.37Å; G34-K37 PolarHBondContact O-N 3.37Å; K37-G41 WeakPolarHBondContact O-CA 3.41Å; K37-G41 PolarHBondContact O-N 3.2Å; K37-G41 VanDerWaalsContact O-N 3.14Å
38L64.3Low74.7Confident153 Ų15384.2 Ų84.280%0.80145%0.45SS*.Hα-helixtrans-70.6-37.6175.1-70.5166.3000112.9G34 K35 E36G34-L38 WeakPolarHBondContact O-CG 3.16Å; G34-L38 PolarHBondContact O-N 3.48Å; K35-L38 PolarHBondContact O-N 2.67Å; E36-L38 PolarHBondContact O-N 2.71Å
39K65Low75.1Confident173 Ų17379.5 Ų79.575%0.75243%0.432SS*.Hα-helixtrans-77.9-40.3-177.6-79.6-174.4176.6-176.20114.2K35 E36K35-K39 PolarHBondContact O-N 2.84Å; E36-K39 PolarHBondContact O-N 2.85Å; E36-K39 VanDerWaalsContact O-N 3.11Å
40H63.5Low75.4Confident132 Ų13281.3 Ų81.361%0.61144%0.441SS*.Hα-helixtrans-110.4-5.2-172.4-68.7-64.1000114.2E36 T42E36-H40 PolarHBondContact O-N 2.81Å; H40-T42 PolarHBondContact O-N 3.05Å
41G59.6Low75.7Confident67 Ų6778.2 Ų78.269%0.69143%0.429SS*.SBendtrans67.7-4.7179.700000115.1K37K37-G41 WeakPolarHBondContact O-CA 3.41Å; K37-G41 PolarHBondContact O-N 3.2Å; K37-G41 VanDerWaalsContact O-N 3.14Å
42T59.1Low75.8Confident99 Ų9980.9 Ų80.961%0.60744%0.439SS*.PPolyproline II helixtrans-102.8131.818042.90000110.8H40H40-T42 PolarHBondContact O-N 3.05Å
43S68.7Low76Confident87 Ų8781.3 Ų81.361%0.60843%0.431SS*.PPolyproline II helixtrans-72.3146.3166.155.10000109.8
44V73.5Confident76.5Confident35 Ų3582.2 Ų82.221%0.21243%0.434CS..PPolyproline II helixtrans-57143.4168.3-72.60000111L33 W46 Y48L33-V44 HydrophobicContact CD2-CG1 3.78Å; V44-W46 WeakPolarHBondContact CG2-O 3.46Å; V44-W46 PolarHBondContact O-N 3.01Å; V44-Y48 HydrophobicContact CG2-CD1 4.47Å
45P77.8Confident77Confident81 Ų8183.9 Ų83.953%0.52643%0.434SS..SBendtrans-74.812.2-17629-34.1000114.5L274P45-L274 HydrophobicContact CB-CB 4.36Å; P45-L274 WeakPolarHBondContact CG-O 3.25Å; P45-L274 PolarHBondContact O-N 2.81Å
46W81.9Confident77.3Confident19 Ų1979.6 Ų79.67%0.07243%0.428CS..EExtended strand (participates in β ladder)trans-136.5151.4-17859.7-79.1000110.8L33 V44 Y48 D266 Y270 Q272 F275L33-W46 HydrophobicContact CD1-CH2 4.47Å; L33-W46 HydrophobicContact CD1-CZ2 4.33Å; V44-W46 WeakPolarHBondContact CG2-O 3.46Å; V44-W46 PolarHBondContact O-N 3.01Å; W46-Y48 HydrophobicContact CZ3-CG 4.37Å; W46-D266 HydrophobicContact CH2-CB 4.38Å; W46-Y270 HydrophobicContact CB-CD2 4.07Å; W46-Y270 HydrophobicContact CB-CE2 4.02Å; W46-Y270 HydrophobicContact CD2-CD2 4.34Å; W46-Y270 AromaticContact CE3-CD2 3.8Å; W46-Y270 HydrophobicContact CE3-CD2 3.8Å; W46-Y270 HydrophobicContact CE3-CG 4.47Å; W46-Y270 HydrophobicContact CG-CD2 4.46Å; W46-Q272 CarbonylContact C-O 3.57Å; W46-Q272 VanDerWaalsContact CA-O 3.25Å; W46-Q272 WeakPolarHBondContact CA-O 3.04Å; W46-Q272 WeakPolarHBondContact CB-O 3.46Å; W46-F275 AromaticContact CD2-CD2 3.87Å; W46-F275 HydrophobicContact CD2-CD2 3.87Å; W46-F275 HydrophobicContact CD2-CE2 4.4Å; W46-F275 AromaticContact CE2-CD2 3.83Å; W46-F275 AromaticContact CE2-CE2 3.98Å; W46-F275 HydrophobicContact CE3-CD2 4.11Å; W46-F275 HydrophobicContact CG-CD2 4.29Å; W46-F275 HydrophobicContact CH2-CD2 4.33Å; W46-F275 AromaticContact CH2-CE2 3.96Å; W46-F275 HydrophobicContact CH2-CE2 3.96Å; W46-F275 HydrophobicContact CZ2-CD2 4.11Å; W46-F275 AromaticContact CZ2-CE2 3.79Å; W46-F275 HydrophobicContact CZ2-CE2 3.79Å; W46-F275 HydrophobicContact CZ3-CD2 4.28Å; W46-F275 HydrophobicContact CZ3-CE2 4.3Å
47K86Confident78Confident122 Ų12277.7 Ų77.753%0.5342%0.419SS..EExtended strand (participates in β ladder)trans-92.1143.3170.4-55.3-169.8-168.2159.70109.6K271 Q272K47-K271 PolarHBondContact O-N 3.4Å; K47-Q272 HydrophobicContact CB-CG 3.64Å; K47-Q272 HydrophobicContact CD-CG 3.69Å; K47-Q272 VanDerWaalsContact CE-CD 3.48Å; K47-Q272 HydrophobicContact CG-CG 3.7Å; K47-Q272 PolarHBondContact N-O 2.88Å; K47-Q272 VanDerWaalsContact NZ-NE2 3.13Å; K47-Q272 VanDerWaalsContact NZ-OE1 3.1Å; K47-Q272 PolarHBondContact O-N 2.87Å
48Y88.2Confident78.8Confident78 Ų7873.4 Ų73.431%0.30641%0.406SS..EExtended strand (participates in β ladder)trans-126.3154-178.863.8-86.1000112.1F26 K30 L33 V44 W46 Y269F26-Y48 AromaticContact CE2-CD2 3.85Å; F26-Y48 HydrophobicContact CE2-CD2 3.85Å; F26-Y48 HydrophobicContact CE2-CE2 4.37Å; F26-Y48 HydrophobicContact CZ-CD2 4.34Å; K30-Y48 HydrophobicContact CB-CE2 4.29Å; K30-Y48 HydrophobicContact CG-CE2 4.37Å; L33-Y48 HydrophobicContact CB-CE1 4.41Å; L33-Y48 HydrophobicContact CD1-CD1 3.66Å; L33-Y48 HydrophobicContact CD1-CD2 4.1Å; L33-Y48 HydrophobicContact CD1-CE1 3.55Å; L33-Y48 HydrophobicContact CD1-CE2 4.02Å; L33-Y48 HydrophobicContact CD1-CG 3.95Å; V44-Y48 HydrophobicContact CG2-CD1 4.47Å; W46-Y48 HydrophobicContact CZ3-CG 4.37Å; Y48-Y269 CarbonylContact C-O 3.38Å; Y48-Y269 WeakPolarHBondContact CA-O 3.49Å; Y48-Y269 WeakPolarHBondContact CB-O 3.3Å
49G90.9Very high79.6Confident12 Ų1268.9 Ų68.912%0.12438%0.382CS..  trans178.9167.6179.500000112N51 Y269G49-N51 PolarHBondContact O-N 3.33Å; G49-Y269 PolarHBondContact N-O 3.16Å; G49-Y269 CarbonylContact O-C 3.51Å; G49-Y269 WeakPolarHBondContact O-CA 3.26Å; G49-Y269 VanDerWaalsContact O-O 3.13Å
50L90.7Very high80.4Confident58 Ų5863.9 Ų63.930%0.30437%0.369SS..  trans-63.2132174.9-66.6172.1000111Y22 E23 F26 M55 Y269 K271Y22-L50 HydrophobicContact CD1-CD2 4Å; Y22-L50 HydrophobicContact CE1-CB 4.36Å; Y22-L50 HydrophobicContact CE1-CD2 3.57Å; E23-L50 HydrophobicContact CG-CD2 4.49Å; F26-L50 HydrophobicContact CB-CD2 3.61Å; F26-L50 HydrophobicContact CB-CG 4.47Å; F26-L50 HydrophobicContact CD1-CD1 4.29Å; F26-L50 HydrophobicContact CD1-CD2 3.96Å; F26-L50 HydrophobicContact CD1-CG 3.88Å; F26-L50 HydrophobicContact CD2-CD2 4.1Å; F26-L50 HydrophobicContact CD2-CG 4.37Å; F26-L50 HydrophobicContact CE1-CG 4.16Å; F26-L50 HydrophobicContact CG-CD2 3.62Å; F26-L50 HydrophobicContact CG-CG 3.99Å; L50-M55 HydrophobicContact CB-SD 4Å; L50-M55 HydrophobicContact CD1-SD 4.22Å; L50-M55 HydrophobicContact CD2-SD 4.34Å; L50-M55 HydrophobicContact CG-SD 4.43Å; L50-Y269 HydrophobicContact CD2-CD1 4.42Å; L50-Y269 HydrophobicContact CD2-CE1 4.25Å; L50-K271 WeakPolarHBondContact O-CE 3.38Å; L50-K271 PolarHBondContact O-NZ 3.16Å
51N89.8Confident81.3Confident33 Ų3359.6 Ų59.618%0.17635%0.35CS..  trans-104.2124.1176-76.9-54.3000110Y22 G49 Y53 F54 M55 M268 Y270 K271Y22-N51 WeakPolarHBondContact OH-CB 3.42Å; Y22-N51 PolarHBondContact OH-N 2.9Å; G49-N51 PolarHBondContact O-N 3.33Å; N51-Y53 PolarHBondContact O-N 3.48Å; N51-F54 HydrophobicContact CB-CD2 3.95Å; N51-F54 PolarHBondContact O-N 3.01Å; N51-M55 PolarHBondContact O-N 3.25Å; N51-M268 PolarHBondContact ND2-O 2.84Å; N51-Y270 PolarHBondContact ND2-O 2.74Å; N51-K271 WeakPolarHBondContact OD1-CD 3.37Å; N51-K271 WeakPolarHBondContact OD1-CE 3.27Å; N51-K271 PolarHBondContact OD1-NZ 2.97Å
52D86.6Confident82.5Confident115 Ų11556.7 Ų56.762%0.61532%0.319SS*.THydrogen-bonded Turntrans-50.8-30.3-179-66.86.3000113.9F54D52-F54 VanDerWaalsContact C-N 3.32Å; D52-F54 PolarHBondContact O-N 3.12Å
53Y84.7Confident83.7Confident74 Ų7459.7 Ų59.729%0.2932%0.319SS..THydrogen-bonded Turntrans-65.5-30.7179.2-174-95000113.6N51 K57 L65 S120N51-Y53 PolarHBondContact O-N 3.48Å; Y53-K57 WeakPolarHBondContact O-CE 3.46Å; Y53-L65 HydrophobicContact CE1-CD1 3.85Å; Y53-S120 PolarHBondContact OH-O 3.42Å; Y53-S120 VanDerWaalsContact OH-O 3.11Å
54F86.9Confident84.5Confident41 Ų4158.3 Ų58.318%0.1831%0.305CS..THydrogen-bonded Turntrans-101.5-6.4-178.6-59.6-65.1000113.6Y22 N51 D52 G56 K57 I62 L65 M268Y22-F54 HydrophobicContact CD1-CB 3.75Å; Y22-F54 WeakPolarHBondContact CD1-O 3.28Å; Y22-F54 HydrophobicContact CD2-CB 3.69Å; Y22-F54 HydrophobicContact CD2-CG 4.44Å; Y22-F54 HydrophobicContact CE1-CB 3.66Å; Y22-F54 HydrophobicContact CE2-CB 3.6Å; Y22-F54 HydrophobicContact CE2-CD2 4.07Å; Y22-F54 HydrophobicContact CE2-CG 4.1Å; Y22-F54 HydrophobicContact CG-CB 3.77Å; N51-F54 HydrophobicContact CB-CD2 3.95Å; N51-F54 PolarHBondContact O-N 3.01Å; D52-F54 VanDerWaalsContact C-N 3.32Å; D52-F54 PolarHBondContact O-N 3.12Å; F54-G56 PolarHBondContact O-N 3.47Å; F54-K57 HydrophobicContact CD1-CD 4.37Å; F54-K57 WeakPolarHBondContact O-CB 3.41Å; F54-K57 PolarHBondContact O-N 2.99Å; F54-K57 VanDerWaalsContact O-N 3.07Å; F54-I62 HydrophobicContact CD1-CD1 4.49Å; F54-I62 HydrophobicContact CD1-CG1 4.21Å; F54-L65 HydrophobicContact CE1-CD1 4.49Å; F54-M268 HydrophobicContact CD2-CB 4.17Å; F54-M268 HydrophobicContact CE2-CB 4.16Å
55M86Confident85.2Confident66 Ų6657.1 Ų57.133%0.32530%0.297SS..THydrogen-bonded Turntrans-56.3131.6177.2-65.9-62.9-65.300110.4Y22 E23 L50 N51 K57Y22-M55 HydrophobicContact CD1-SD 4.23Å; Y22-M55 HydrophobicContact CE1-SD 4.12Å; E23-M55 HydrophobicContact CG-CE 3.7Å; E23-M55 HydrophobicContact CG-SD 4Å; E23-M55 WeakPolarHBondContact OE1-CA 3.25Å; E23-M55 VanDerWaalsContact OE1-CE 3.26Å; E23-M55 WeakPolarHBondContact OE1-CE 3.36Å; L50-M55 HydrophobicContact CB-SD 4Å; L50-M55 HydrophobicContact CD1-SD 4.22Å; L50-M55 HydrophobicContact CD2-SD 4.34Å; L50-M55 HydrophobicContact CG-SD 4.43Å; N51-M55 PolarHBondContact O-N 3.25Å; M55-K57 VanDerWaalsContact C-N 3.29Å; M55-K57 PolarHBondContact O-N 3.26Å
56G83Confident85.7Confident42 Ų4257.1 Ų57.143%0.43329%0.292SS..THydrogen-bonded Turntrans81.6-11-177.900000116S20 E23 F54S20-G56 WeakPolarHBondContact OG-CA 3.35Å; S20-G56 PolarHBondContact OG-N 3.49Å; E23-G56 PolarHBondContact OE1-N 2.74Å; F54-G56 PolarHBondContact O-N 3.47Å
57K84Confident86Confident11 Ų1156.5 Ų56.55%0.04829%0.292CS..  trans-82.4140.9-173.9-67.3-172.2-175.7-78.30112.6Y53 F54 M55 D61 I62 L65 N121Y53-K57 WeakPolarHBondContact O-CE 3.46Å; F54-K57 HydrophobicContact CD1-CD 4.37Å; F54-K57 WeakPolarHBondContact O-CB 3.41Å; F54-K57 PolarHBondContact O-N 2.99Å; F54-K57 VanDerWaalsContact O-N 3.07Å; M55-K57 VanDerWaalsContact C-N 3.29Å; M55-K57 PolarHBondContact O-N 3.26Å; K57-D61 HydrophobicContact CB-CB 4.15Å; K57-D61 HydrophobicContact CG-CB 4.45Å; K57-I62 HydrophobicContact CB-CD1 4.32Å; K57-I62 HydrophobicContact CB-CG1 3.98Å; K57-I62 HydrophobicContact CD-CG1 4.48Å; K57-L65 HydrophobicContact CD-CD1 4.3Å; K57-N121 PolarHBondContact NZ-OD1 2.81Å
58S83.6Confident85.9Confident44 Ų4452.1 Ų52.131%0.30827%0.273SS..  trans-78.7164.3169.673.40000111.6S60 D61 I62S58-S60 PolarHBondContact O-N 3.22Å; S58-S60 PolarHBondContact OG-N 2.79Å; S58-D61 VanDerWaalsContact CB-OD2 3.29Å; S58-D61 WeakPolarHBondContact CB-OD2 2.99Å; S58-D61 PolarHBondContact N-OD2 3.43Å; S58-D61 PolarHBondContact O-N 3.15Å; S58-D61 PolarHBondContact OG-N 2.95Å; S58-D61 VanDerWaalsContact OG-N 3.11Å; S58-D61 PolarHBondContact OG-OD2 3.33Å; S58-I62 WeakPolarHBondContact O-CG1 3.28Å; S58-I62 PolarHBondContact O-N 3.19Å; S58-I62 VanDerWaalsContact O-N 3.07Å
59L81.6Confident85Confident57 Ų5751.8 Ų51.830%0.29828%0.28SS..Hα-helixtrans-58-35172.2179.559.4000111.9F21 I62 R63F21-L59 HydrophobicContact CD1-CB 3.69Å; F21-L59 HydrophobicContact CD1-CD1 4.44Å; F21-L59 HydrophobicContact CD2-CB 4.16Å; F21-L59 HydrophobicContact CE1-CB 3.74Å; F21-L59 HydrophobicContact CE1-CD1 3.66Å; F21-L59 HydrophobicContact CE1-CG 4.18Å; F21-L59 HydrophobicContact CE2-CB 4.21Å; F21-L59 HydrophobicContact CE2-CD2 4.28Å; F21-L59 HydrophobicContact CG-CB 3.92Å; F21-L59 HydrophobicContact CZ-CB 4.01Å; F21-L59 HydrophobicContact CZ-CD1 3.8Å; F21-L59 HydrophobicContact CZ-CD2 4.15Å; F21-L59 HydrophobicContact CZ-CG 4.2Å; L59-I62 PolarHBondContact O-N 3.49Å; L59-R63 HydrophobicContact CD1-CG 4.42Å; L59-R63 WeakPolarHBondContact O-CB 3.46Å; L59-R63 WeakPolarHBondContact O-CG 3.43Å; L59-R63 PolarHBondContact O-N 3.45Å
60S81.4Confident83.4Confident68 Ų6854.1 Ų54.148%0.47629%0.289SS..Hα-helixtrans-66.2-45.4176.6-1680000111.4S58 I62 R63 N64S58-S60 PolarHBondContact O-N 3.22Å; S58-S60 PolarHBondContact OG-N 2.79Å; S60-I62 VanDerWaalsContact C-N 3.27Å; S60-I62 PolarHBondContact O-N 3Å; S60-R63 PolarHBondContact O-N 2.04Å; S60-N64 PolarHBondContact O-N 3.1Å; S60-N64 PolarHBondContact O-ND2 3.07Å; S60-N64 VanDerWaalsContact O-ND2 3.13Å; S60-N64 PolarHBondContact O-OD1 2.84Å
61D83.1Confident81.5Confident42 Ų4257.6 Ų57.623%0.22530%0.304CS..Hα-helixtrans-59.7-41.9177.9-59.9-49.2000110.9K57 S58 N64 L65K57-D61 HydrophobicContact CB-CB 4.15Å; K57-D61 HydrophobicContact CG-CB 4.45Å; S58-D61 VanDerWaalsContact CB-OD2 3.29Å; S58-D61 WeakPolarHBondContact CB-OD2 2.99Å; S58-D61 PolarHBondContact N-OD2 3.43Å; S58-D61 PolarHBondContact O-N 3.15Å; S58-D61 PolarHBondContact OG-N 2.95Å; S58-D61 VanDerWaalsContact OG-N 3.11Å; S58-D61 PolarHBondContact OG-OD2 3.33Å; D61-N64 PolarHBondContact O-N 3.27Å; D61-L65 WeakPolarHBondContact O-CG 2.99Å; D61-L65 PolarHBondContact O-N 2.87Å
62I84.8Confident79.5Confident7 Ų760.7 Ų60.74%0.03633%0.326CS..Hα-helixtrans-65.1-46.4178.1-66169.7000110.8F21 Y22 F54 K57 S58 L59 S60 N64 L65 M268F21-I62 HydrophobicContact CD1-CD1 4.35Å; Y22-I62 HydrophobicContact CD2-CD1 4.49Å; F54-I62 HydrophobicContact CD1-CD1 4.49Å; F54-I62 HydrophobicContact CD1-CG1 4.21Å; K57-I62 HydrophobicContact CB-CD1 4.32Å; K57-I62 HydrophobicContact CB-CG1 3.98Å; K57-I62 HydrophobicContact CD-CG1 4.48Å; S58-I62 WeakPolarHBondContact O-CG1 3.28Å; S58-I62 PolarHBondContact O-N 3.19Å; S58-I62 VanDerWaalsContact O-N 3.07Å; L59-I62 PolarHBondContact O-N 3.49Å; S60-I62 VanDerWaalsContact C-N 3.27Å; S60-I62 PolarHBondContact O-N 3Å; I62-N64 VanDerWaalsContact C-N 3.26Å; I62-N64 PolarHBondContact O-N 2.63Å; I62-L65 WeakPolarHBondContact O-CB 3.47Å; I62-L65 PolarHBondContact O-N 3.17Å; I62-L65 VanDerWaalsContact O-N 3.1Å; I62-M268 HydrophobicContact CB-SD 4.4Å; I62-M268 HydrophobicContact CD1-CE 4.3Å; I62-M268 HydrophobicContact CD1-SD 3.57Å; I62-M268 VanDerWaalsContact CD1-SD 3.57Å; I62-M268 HydrophobicContact CG1-SD 4.33Å; I62-M268 HydrophobicContact CG2-SD 3.43Å; I62-M268 WeakPolarHBondContact CG2-SD 3.31Å
63R85.1Confident77.5Confident161 Ų16156.8 Ų56.861%0.60831%0.31SS*.Hα-helixtrans-59.3-37.9177.1-78.6177.9177.1160.3-2112.1L59 S60 L65 L66L59-R63 HydrophobicContact CD1-CG 4.42Å; L59-R63 WeakPolarHBondContact O-CB 3.46Å; L59-R63 WeakPolarHBondContact O-CG 3.43Å; L59-R63 PolarHBondContact O-N 3.45Å; S60-R63 PolarHBondContact O-N 2.04Å; R63-L65 PolarHBondContact O-N 3.42Å; R63-L66 WeakPolarHBondContact O-CB 3.06Å; R63-L66 PolarHBondContact O-N 2.95Å
64N84.8Confident75.7Confident58 Ų5856 Ų5631%0.3131%0.313SS..Hα-helixtrans-66.6-22178.4-64.2-24000113.3S60 D61 I62 L66 G123 N209S60-N64 PolarHBondContact O-N 3.1Å; S60-N64 PolarHBondContact O-ND2 3.07Å; S60-N64 VanDerWaalsContact O-ND2 3.13Å; S60-N64 PolarHBondContact O-OD1 2.84Å; D61-N64 PolarHBondContact O-N 3.27Å; I62-N64 VanDerWaalsContact C-N 3.26Å; I62-N64 PolarHBondContact O-N 2.63Å; N64-L66 VanDerWaalsContact C-N 3.3Å; N64-G123 WeakPolarHBondContact O-CA 3.34Å; N64-G123 PolarHBondContact O-N 2.92Å; N64-N209 WeakPolarHBondContact CB-OD1 3.48Å; N64-N209 PolarHBondContact ND2-ND2 2.71Å; N64-N209 PolarHBondContact ND2-OD1 2.62Å; N64-N209 VanDerWaalsContact ND2-OD1 3.09Å
65L87.9Confident73.5Confident10 Ų1061.7 Ų61.75%0.05234%0.34CS..Hα-helixtrans-75.5-20.5171.7-59.4175.3000112.4Y53 F54 K57 D61 I62 R63 G67 Q119 S120Y53-L65 HydrophobicContact CE1-CD1 3.85Å; F54-L65 HydrophobicContact CE1-CD1 4.49Å; K57-L65 HydrophobicContact CD-CD1 4.3Å; D61-L65 WeakPolarHBondContact O-CG 2.99Å; D61-L65 PolarHBondContact O-N 2.87Å; I62-L65 WeakPolarHBondContact O-CB 3.47Å; I62-L65 PolarHBondContact O-N 3.17Å; I62-L65 VanDerWaalsContact O-N 3.1Å; R63-L65 PolarHBondContact O-N 3.42Å; L65-G67 PolarHBondContact O-N 3.35Å; L65-Q119 PolarHBondContact O-NE2 3.41Å; L65-S120 WeakPolarHBondContact CD2-O 3.44Å
66L89.1Confident71.4Confident81 Ų8162.1 Ų62.142%0.42435%0.35SS..  trans-84.662.3-179-54.2-177.9000111R63 N64 Y68 V263R63-L66 WeakPolarHBondContact O-CB 3.06Å; R63-L66 PolarHBondContact O-N 2.95Å; N64-L66 VanDerWaalsContact C-N 3.3Å; L66-Y68 PolarHBondContact O-N 3.27Å; L66-V263 HydrophobicContact CD1-CB 4.06Å; L66-V263 HydrophobicContact CD1-CG1 4.48Å; L66-V263 HydrophobicContact CD1-CG2 4.47Å; L66-V263 HydrophobicContact CD2-CB 4.29Å; L66-V263 HydrophobicContact CD2-CG2 3.93Å
67G88Confident69.7Low7 Ų761 Ų617%0.07233%0.334CS..  trans-74.420.7-175.700000116.3L65 P69 G123 C125 G168 G169L65-G67 PolarHBondContact O-N 3.35Å; G67-P69 WeakPolarHBondContact O-CD 3Å; G67-G123 WeakPolarHBondContact CA-O 3.29Å; G67-C125 PolarHBondContact N-SG 3.38Å; G67-C125 VanDerWaalsContact N-SG 3.44Å; G67-G168 CarbonylContact O-C 3.53Å; G67-G168 WeakPolarHBondContact O-CA 3.37Å; G67-G169 PolarHBondContact O-N 3.31Å
68Y84.4Confident68.1Low30 Ų3067 Ų6712%0.11836%0.356CS..  trans-107.4101.4170.3-177.4-140.9000108.8L66 L70 G169 Y170 P171 Y289L66-Y68 PolarHBondContact O-N 3.27Å; Y68-L70 HydrophobicContact CD1-CD2 3.75Å; Y68-L70 HydrophobicContact CD1-CG 4.35Å; Y68-L70 HydrophobicContact CE1-CD2 3.55Å; Y68-L70 PolarHBondContact O-N 3.41Å; Y68-G169 WeakPolarHBondContact CD2-O 3.32Å; Y68-Y170 HydrophobicContact CD2-CD2 4.44Å; Y68-Y170 AromaticContact CE2-CD2 3.57Å; Y68-Y170 HydrophobicContact CE2-CD2 3.57Å; Y68-Y170 AromaticContact CE2-CE2 3.74Å; Y68-Y170 HydrophobicContact CE2-CE2 3.74Å; Y68-Y170 HydrophobicContact CE2-CG 4.46Å; Y68-P171 HydrophobicContact CD2-CG 4.25Å; Y68-P171 HydrophobicContact CE2-CG 4.18Å; Y68-Y289 HydrophobicContact CE1-CD1 4.1Å; Y68-Y289 HydrophobicContact CE1-CG 4.35Å
69P68Low66.5Low71 Ų7170.2 Ų70.246%0.46137%0.374SS..  trans-66108.5174.727-31.7000108G67 E71G67-P69 WeakPolarHBondContact O-CD 3Å; P69-E71 VanDerWaalsContact C-N 3.26Å; P69-E71 PolarHBondContact O-N 3.16Å
70L58.8Low65.4Low60 Ų6071 Ų7131%0.31438%0.376SS..  trans-74.185.7172.1-70.3169.4000108.2Y68 T262 Y289Y68-L70 HydrophobicContact CD1-CD2 3.75Å; Y68-L70 HydrophobicContact CD1-CG 4.35Å; Y68-L70 HydrophobicContact CE1-CD2 3.55Å; Y68-L70 PolarHBondContact O-N 3.41Å; L70-T262 WeakPolarHBondContact CD1-OG1 3.43Å; L70-Y289 HydrophobicContact CD2-CD1 3.63Å; L70-Y289 HydrophobicContact CD2-CD2 4.05Å; L70-Y289 HydrophobicContact CD2-CE1 3.64Å; L70-Y289 HydrophobicContact CD2-CE2 4.06Å; L70-Y289 HydrophobicContact CD2-CG 3.83Å
71E49.6Very low64.7Low131 Ų13168 Ų6861%0.61235%0.354SS*.  trans-81.5137.2158.6-70.9-174.7-179.300108.5P69 A73P69-E71 VanDerWaalsContact C-N 3.26Å; P69-E71 PolarHBondContact O-N 3.16Å; E71-A73 PolarHBondContact O-N 2.84Å
72P47.9Very low64Low98 Ų9866.6 Ų66.664%0.63635%0.348SS*.  trans-53.9132.5170.6-18.929.1000109.1T74P72-T74 PolarHBondContact O-N 3.19Å
73A44.8Very low63.4Low34 Ų3466.5 Ų66.528%0.28135%0.347SS..  trans-55.7109.8176.700000109.7E71 D77E71-A73 PolarHBondContact O-N 2.84Å; A73-D77 WeakPolarHBondContact CA-OD2 3.45Å
74T46Very low62.4Low58 Ų5859.2 Ų59.236%0.35632%0.321SS..  trans-73.9162.2178.7660000110.3P72 S76 D77 R78P72-T74 PolarHBondContact O-N 3.19Å; T74-S76 PolarHBondContact O-N 3.19Å; T74-S76 PolarHBondContact OG1-OG 2.84Å; T74-D77 PolarHBondContact N-OD2 3.47Å; T74-D77 PolarHBondContact O-N 2.92Å; T74-D77 PolarHBondContact OG1-N 2.99Å; T74-D77 PolarHBondContact OG1-OD1 3.25Å; T74-R78 PolarHBondContact O-N 3.45Å
75E42.1Very low61.4Low160 Ų16060.2 Ų60.275%0.74833%0.326SS*.THydrogen-bonded Turntrans-56-35.1171.5-162.6101.9-157.500111R78E75-R78 PolarHBondContact O-N 2.84Å
76S42.3Very low59.9Low75 Ų7561.5 Ų61.552%0.52433%0.332SS..THydrogen-bonded Turntrans-63.2-39.8173.330.40000113.1T74 R78 T79 E80T74-S76 PolarHBondContact O-N 3.19Å; T74-S76 PolarHBondContact OG1-OG 2.84Å; S76-R78 VanDerWaalsContact C-N 3.27Å; S76-R78 PolarHBondContact O-N 3.38Å; S76-T79 PolarHBondContact O-N 2.84Å; S76-T79 PolarHBondContact O-OG1 3.32Å; S76-E80 PolarHBondContact O-N 2.87Å
77D47.3Very low58.1Low19 Ų1957.9 Ų57.910%0.10231%0.313CS..Hα-helixtrans-65.5-32-179.4-58.1-9.4000112.6A73 T74 T79 E80 F81 R239A73-D77 WeakPolarHBondContact CA-OD2 3.45Å; T74-D77 PolarHBondContact N-OD2 3.47Å; T74-D77 PolarHBondContact O-N 2.92Å; T74-D77 PolarHBondContact OG1-N 2.99Å; T74-D77 PolarHBondContact OG1-OD1 3.25Å; D77-T79 PolarHBondContact O-N 2.81Å; D77-E80 PolarHBondContact O-N 3.29Å; D77-F81 PolarHBondContact O-N 3.26Å; D77-R239 VanDerWaalsContact CB-NH1 3.26Å; D77-R239 IonicContact OD2-NH1 3.36Å; D77-R239 PolarHBondContact OD2-NH1 2.95Å
78R50.5Low56.2Low135 Ų13558.7 Ų58.751%0.50932%0.32SS..Hα-helixtrans-64.9-22175.3-63.6-176.7-176.3-164.8-0.7112.3T74 E75 S76T74-R78 PolarHBondContact O-N 3.45Å; E75-R78 PolarHBondContact O-N 2.84Å; S76-R78 VanDerWaalsContact C-N 3.27Å; S76-R78 PolarHBondContact O-N 3.38Å
79T50.1Low54Low113 Ų11359.7 Ų59.769%0.69333%0.332SS*.Hα-helixtrans-97.7-18.3175.564.20000113S76 D77S76-T79 PolarHBondContact O-N 2.84Å; S76-T79 PolarHBondContact O-OG1 3.32Å; D77-T79 PolarHBondContact O-N 2.81Å
80E58.4Low52.8Low74 Ų7460.9 Ų60.935%0.34633%0.331SS..Hα-helixtrans-73.1-37.3179.7-170-177.4167.500111.9S76 D77 R173S76-E80 PolarHBondContact O-N 2.87Å; D77-E80 PolarHBondContact O-N 3.29Å; E80-R173 IonicContact OE1-CZ 2.68Å; E80-R173 IonicContact OE1-NE 3.66Å; E80-R173 PolarHBondContact OE1-NE 3.32Å; E80-R173 IonicContact OE1-NH2 2.86Å; E80-R173 PolarHBondContact OE1-NH2 3.33Å; E80-R173 VanDerWaalsContact OE1-NH2 3.11Å; E80-R173 IonicContact OE2-NH2 2.97Å; E80-R173 PolarHBondContact OE2-NH2 2.83Å
81F65.6Low51.8Low3 Ų361.2 Ų61.21%0.01334%0.339CS..SBendtrans-121.6137.2-179.7-60.8-81.2000111.2D77 Y170 P172 R173 L176 Y237 R239 W241D77-F81 PolarHBondContact O-N 3.26Å; F81-Y170 HydrophobicContact CE2-CD1 4.37Å; F81-Y170 AromaticContact CE2-CE1 3.91Å; F81-Y170 HydrophobicContact CE2-CE1 3.91Å; F81-Y170 HydrophobicContact CZ-CE1 4.49Å; F81-P172 HydrophobicContact CD1-CB 3.77Å; F81-P172 HydrophobicContact CD2-CB 3.91Å; F81-P172 HydrophobicContact CE1-CB 3.61Å; F81-P172 WeakPolarHBondContact CE1-O 3.12Å; F81-P172 HydrophobicContact CE2-CB 3.75Å; F81-P172 HydrophobicContact CG-CB 3.94Å; F81-P172 HydrophobicContact CZ-CB 3.62Å; F81-R173 HydrophobicContact CE1-CG 4.34Å; F81-R173 HydrophobicContact CZ-CG 3.6Å; F81-L176 HydrophobicContact CE1-CB 4.36Å; F81-Y237 AromaticContact CD1-CD2 3.83Å; F81-Y237 HydrophobicContact CD1-CD2 3.83Å; F81-Y237 AromaticContact CD1-CE2 3.83Å; F81-Y237 HydrophobicContact CD1-CE2 3.83Å; F81-Y237 HydrophobicContact CE1-CD2 4.24Å; F81-Y237 HydrophobicContact CE1-CE2 4.22Å; F81-R239 HydrophobicContact CB-CB 3.76Å; F81-R239 HydrophobicContact CG-CB 4.4Å; F81-W241 WeakPolarHBondContact O-CH2 3.3Å; F81-W241 WeakPolarHBondContact O-CZ3 3.5Å
82P67.9Low51.5Low14 Ų1459 Ų599%0.09134%0.338CS..  trans-73158.7173.931-37.5000112.7Y87 Y237 Y238 R239 W241 L317P82-Y87 HydrophobicContact CG-CE1 4.42Å; P82-Y87 HydrophobicContact CG-CE2 4.44Å; P82-Y87 WeakPolarHBondContact CG-OH 3.15Å; P82-Y237 VanDerWaalsContact CG-O 3.27Å; P82-Y237 WeakPolarHBondContact CG-O 3.34Å; P82-Y238 VanDerWaalsContact O-CA 3.25Å; P82-Y238 WeakPolarHBondContact O-CA 3.33Å; P82-Y238 WeakPolarHBondContact O-CB 3.41Å; P82-R239 PolarHBondContact O-N 2.8Å; P82-W241 VanDerWaalsContact C-CZ3 3.41Å; P82-L317 HydrophobicContact CB-CB 4.39Å; P82-L317 HydrophobicContact CB-CD2 3.67Å; P82-L317 HydrophobicContact CG-CD2 4.27Å
83H72.3Confident51.5Low5 Ų565.1 Ų65.12%0.02335%0.348CS..  trans-84.6150.6173.9-159.2-108.7000110.5D85 E86 W241H83-D85 VanDerWaalsContact C-N 3.27Å; H83-D85 IonicContact CE1-OD2 2.99Å; H83-D85 PolarHBondContact CE1-OD2 3.44Å; H83-D85 WeakPolarHBondContact ND1-CB 3.15Å; H83-D85 PolarHBondContact ND1-N 3.11Å; H83-D85 IonicContact ND1-OD2 3.63Å; H83-D85 PolarHBondContact ND1-OD2 2.85Å; H83-D85 VanDerWaalsContact ND1-OD2 3.12Å; H83-D85 PolarHBondContact O-N 3.1Å; H83-E86 HydrophobicContact CB-CG 3.99Å; H83-E86 WeakPolarHBondContact CB-OE1 3.14Å; H83-E86 PolarHBondContact N-OE1 3.29Å; H83-E86 WeakPolarHBondContact O-CA 3.32Å; H83-E86 WeakPolarHBondContact O-CB 3.14Å; H83-E86 PolarHBondContact O-N 3.04Å; H83-W241 VanDerWaalsContact CA-CH2 3.49Å; H83-W241 HydrophobicContact CB-CE3 4.47Å; H83-W241 HydrophobicContact CB-CH2 3.5Å; H83-W241 VanDerWaalsContact CB-CH2 3.5Å; H83-W241 HydrophobicContact CB-CZ2 3.46Å; H83-W241 VanDerWaalsContact CB-CZ2 3.46Å; H83-W241 HydrophobicContact CB-CZ3 3.98Å; H83-W241 AromaticContact CD2-CD2 3.59Å; H83-W241 AromaticContact CD2-CE2 3.69Å; H83-W241 AromaticContact CD2-CE3 3.81Å
84P64.4Low52.4Low7 Ų765.8 Ų65.85%0.04535%0.346CS..G310 helixtrans-56-38.4172.8-3.9-2.5000114.1E86 Y87 Y238 R239 F240P84-E86 PolarHBondContact O-N 3.49Å; P84-E86 VanDerWaalsContact O-N 3.14Å; P84-Y87 WeakPolarHBondContact O-CD2 3.22Å; P84-Y87 PolarHBondContact O-N 2.57Å; P84-Y238 HydrophobicContact CB-CD2 3.74Å; P84-Y238 HydrophobicContact CB-CE2 3.67Å; P84-Y238 HydrophobicContact CB-CG 4.36Å; P84-Y238 HydrophobicContact CG-CD2 3.48Å; P84-Y238 VanDerWaalsContact CG-CD2 3.48Å; P84-Y238 HydrophobicContact CG-CE2 3.7Å; P84-Y238 HydrophobicContact CG-CG 4.35Å; P84-R239 WeakPolarHBondContact CD-O 3.5Å; P84-F240 HydrophobicContact CB-CE1 4.29Å; P84-F240 HydrophobicContact CG-CD1 3.51Å; P84-F240 HydrophobicContact CG-CE1 3.27Å; P84-F240 HydrophobicContact CG-CE2 4.35Å; P84-F240 HydrophobicContact CG-CG 4.16Å; P84-F240 HydrophobicContact CG-CZ 3.75Å
85D64.5Low53.8Low79 Ų7971.7 Ų71.742%0.42237%0.37SS..G310 helixtrans-65.6-15177.3-63.7-42.6000112.4H83 Y87 S246H83-D85 VanDerWaalsContact C-N 3.27Å; H83-D85 IonicContact CE1-OD2 2.99Å; H83-D85 PolarHBondContact CE1-OD2 3.44Å; H83-D85 WeakPolarHBondContact ND1-CB 3.15Å; H83-D85 PolarHBondContact ND1-N 3.11Å; H83-D85 IonicContact ND1-OD2 3.63Å; H83-D85 PolarHBondContact ND1-OD2 2.85Å; H83-D85 VanDerWaalsContact ND1-OD2 3.12Å; H83-D85 PolarHBondContact O-N 3.1Å; D85-Y87 VanDerWaalsContact C-N 3.28Å; D85-Y87 PolarHBondContact O-N 3.38Å; D85-S246 PolarHBondContact OD2-OG 3.14Å
86E55.3Low55.7Low37 Ų3766.5 Ų66.517%0.17335%0.347CS..G310 helixtrans-71.8-19.5171.5-68.9178-116.400112.7H83 P84 G88 W241 L317 K321H83-E86 HydrophobicContact CB-CG 3.99Å; H83-E86 WeakPolarHBondContact CB-OE1 3.14Å; H83-E86 PolarHBondContact N-OE1 3.29Å; H83-E86 WeakPolarHBondContact O-CA 3.32Å; H83-E86 WeakPolarHBondContact O-CB 3.14Å; H83-E86 PolarHBondContact O-N 3.04Å; P84-E86 PolarHBondContact O-N 3.49Å; P84-E86 VanDerWaalsContact O-N 3.14Å; E86-G88 PolarHBondContact O-N 2.75Å; E86-G88 VanDerWaalsContact O-N 3.13Å; E86-W241 WeakPolarHBondContact OE1-CH2 3.35Å; E86-L317 HydrophobicContact CB-CD2 4.05Å; E86-K321 VanDerWaalsContact C-NZ 3.28Å; E86-K321 HydrophobicContact CB-CD 4.31Å; E86-K321 HydrophobicContact CG-CD 4.47Å; E86-K321 WeakPolarHBondContact O-CE 3.46Å; E86-K321 PolarHBondContact O-NZ 2.81Å
87Y51.6Low57.8Low6 Ų665.3 Ų65.32%0.02434%0.337CS..G310 helixtrans-83.716.8179.4-57.2-64.8000115.6P82 P84 D85 T236 Y237 Y238 L317 I538 N539P82-Y87 HydrophobicContact CG-CE1 4.42Å; P82-Y87 HydrophobicContact CG-CE2 4.44Å; P82-Y87 WeakPolarHBondContact CG-OH 3.15Å; P84-Y87 WeakPolarHBondContact O-CD2 3.22Å; P84-Y87 PolarHBondContact O-N 2.57Å; D85-Y87 VanDerWaalsContact C-N 3.28Å; D85-Y87 PolarHBondContact O-N 3.38Å; Y87-T236 HydrophobicContact CD2-CG2 4.44Å; Y87-T236 HydrophobicContact CE1-CG2 4.4Å; Y87-T236 WeakPolarHBondContact CE1-OG1 3.27Å; Y87-T236 HydrophobicContact CE2-CG2 4.3Å; Y87-T236 PolarHBondContact OH-OG1 2.77Å; Y87-Y237 PolarHBondContact OH-O 3.3Å; Y87-Y238 AromaticContact CD2-CD1 3.91Å; Y87-Y238 HydrophobicContact CD2-CD1 3.91Å; Y87-Y238 HydrophobicContact CD2-CE1 4.28Å; Y87-Y238 HydrophobicContact CD2-CG 4.46Å; Y87-Y238 AromaticContact CE2-CD1 3.21Å; Y87-Y238 HydrophobicContact CE2-CD1 3.21Å; Y87-Y238 HydrophobicContact CE2-CE1 4Å; Y87-Y238 AromaticContact CE2-CG 3.65Å; Y87-Y238 HydrophobicContact CE2-CG 3.65Å; Y87-Y238 AromaticContact CZ-CD1 3.95Å; Y87-L317 HydrophobicContact CD1-CD2 3.73Å; Y87-L317 HydrophobicContact CE1-CD2 3.26Å; Y87-I538 HydrophobicContact CD1-CB 3.58Å; Y87-I538 HydrophobicContact CD1-CD1 3.17Å; Y87-I538 HydrophobicContact CD1-CG1 3.72Å; Y87-I538 HydrophobicContact CD1-CG2 3.68Å; Y87-I538 HydrophobicContact CE1-CB 4.35Å; Y87-I538 HydrophobicContact CE1-CD1 3.08Å; Y87-I538 HydrophobicContact CE1-CG1 4.13Å; Y87-I538 HydrophobicContact CE1-CG2 4.24Å; Y87-I538 HydrophobicContact CG-CB 4.29Å; Y87-I538 HydrophobicContact CG-CD1 4.48Å; Y87-I538 HydrophobicContact CG-CG2 4.2Å; Y87-N539 CarbonylContact C-O 3.46Å; Y87-N539 WeakPolarHBondContact O-CB 3.48Å
88G49.3Very low59.7Low23 Ų2373.7 Ų73.724%0.23738%0.376CS..  trans84.8140.6-179.600000112.6E86 E90E86-G88 PolarHBondContact O-N 2.75Å; E86-G88 VanDerWaalsContact O-N 3.13Å; G88-E90 PolarHBondContact O-N 3.46Å
89S37.4Very low61.6Low52 Ų5275.5 Ų75.536%0.36439%0.39SS..  trans-74.7105.4-178.968.90000110.6S91S89-S91 PolarHBondContact O-N 3.17Å; S89-S91 VanDerWaalsContact O-N 3.13Å
90E42.7Very low63.6Low95 Ų9573.3 Ų73.344%0.44437%0.371SS..SBendtrans-57.6114.3138.8-82.8171.2-147.800105.8G88 I94 K249 L253 Y254G88-E90 PolarHBondContact O-N 3.46Å; E90-I94 HydrophobicContact CB-CD1 4.42Å; E90-K249 PolarHBondContact O-NZ 3.48Å; E90-L253 HydrophobicContact CB-CD1 4.37Å; E90-Y254 PolarHBondContact OE1-OH 2.73Å; E90-Y254 PolarHBondContact OE2-OH 3.15Å
91S37.6Very low65.1Low67 Ų6771.8 Ų71.847%0.46937%0.366SS..  trans21.2114.4179-1730000116.3S89 R93 I94S89-S91 PolarHBondContact O-N 3.17Å; S89-S91 VanDerWaalsContact O-N 3.13Å; S91-R93 PolarHBondContact O-N 2.85Å; S91-R93 PolarHBondContact OG-N 2.88Å; S91-I94 PolarHBondContact O-N 2.85Å
92S43.5Very low66.5Low84 Ų8472.3 Ų72.359%0.58737%0.37SS*.THydrogen-bonded Turntrans-59.74.8169.339.50000114.4
93R47.2Very low67.8Low227 Ų22777.2 Ų77.286%0.85739%0.386SS*.THydrogen-bonded Turntrans-130.345.3177.1-63-172.4-176.9-178.51.8113.6S91 E95S91-R93 PolarHBondContact O-N 2.85Å; S91-R93 PolarHBondContact OG-N 2.88Å; R93-E95 PolarHBondContact O-N 2.66Å
94I63.8Low68.9Low48 Ų4885 Ų8525%0.24642%0.42CS..  trans-80.7108.5164.9-64.8159000107.7E90 S91 L96 Y252 L253E90-I94 HydrophobicContact CB-CD1 4.42Å; S91-I94 PolarHBondContact O-N 2.85Å; I94-L96 HydrophobicContact CG2-CD2 3.98Å; I94-L96 PolarHBondContact O-N 3.3Å; I94-Y252 HydrophobicContact CG2-CD1 3.93Å; I94-Y252 HydrophobicContact CG2-CE1 3.8Å; I94-L253 HydrophobicContact CD1-CD1 3.92Å; I94-L253 HydrophobicContact CD1-CD2 3.89Å; I94-L253 HydrophobicContact CD1-CG 4.34Å
95E76.8Confident70.3Confident182 Ų18288.2 Ų88.285%0.8544%0.437SS*.  trans-72.2113.3169.1-169.1171.4-168.400108.4R93R93-E95 PolarHBondContact O-N 2.66Å
96L81.1Confident71.8Confident51 Ų5186.4 Ų86.427%0.26742%0.424SS..  trans-82.1134.9-179.5-62.2172.4000109.3I94 M248 K249 Y252I94-L96 HydrophobicContact CG2-CD2 3.98Å; I94-L96 PolarHBondContact O-N 3.3Å; L96-M248 HydrophobicContact CD1-CB 3.82Å; L96-K249 HydrophobicContact CD1-CB 4.22Å; L96-K249 HydrophobicContact CD2-CB 4.35Å; L96-Y252 HydrophobicContact CD2-CD1 4Å; L96-Y252 HydrophobicContact CD2-CG 3.88Å
97P86.4Confident73.7Confident50 Ų5088.8 Ų88.833%0.32544%0.443SS..  trans-66.2151.2175.630.2-35.8000110.6Q99 F100 Y252P97-Q99 WeakPolarHBondContact CB-O 3.38Å; P97-Q99 PolarHBondContact O-N 3.31Å; P97-F100 HydrophobicContact CG-CB 4.29Å; P97-F100 HydrophobicContact CG-CD2 4.35Å; P97-Y252 HydrophobicContact CG-CD2 4.18Å; P97-Y252 HydrophobicContact CG-CE2 4.01Å
98E87.5Confident75.7Confident195 Ų19593.3 Ų93.391%0.91147%0.471SS*.SBendtrans-59.8-28.4174.4-71.4-168.1159.100112.7
99Q89.5Confident78Confident173 Ų17392.4 Ų92.481%0.80846%0.461SS*.  trans-131.7135.6177.9-64.2-17939.900110.6P97P97-Q99 WeakPolarHBondContact CB-O 3.38Å; P97-Q99 PolarHBondContact O-N 3.31Å
100F91.9Very high80.8Confident67 Ų6795.3 Ų95.329%0.29447%0.467SS..  trans-140.4138.4177.7-175.7-102.4000110.8P97 N105 W106 I251 Y252P97-F100 HydrophobicContact CG-CB 4.29Å; P97-F100 HydrophobicContact CG-CD2 4.35Å; F100-N105 HydrophobicContact CE2-CB 3.62Å; F100-N105 VanDerWaalsContact CE2-CG 3.44Å; F100-N105 HydrophobicContact CZ-CB 3.63Å; F100-W106 HydrophobicContact CE1-CH2 4.21Å; F100-W106 AromaticContact CE1-CZ3 3.85Å; F100-W106 HydrophobicContact CE1-CZ3 3.85Å; F100-W106 HydrophobicContact CZ-CE3 4.45Å; F100-W106 AromaticContact CZ-CH2 3.63Å; F100-W106 HydrophobicContact CZ-CH2 3.63Å; F100-W106 AromaticContact CZ-CZ3 3.5Å; F100-W106 HydrophobicContact CZ-CZ3 3.5Å; F100-I251 HydrophobicContact CD1-CG2 3.72Å; F100-I251 HydrophobicContact CE1-CG2 3.71Å; F100-I251 WeakPolarHBondContact CE1-O 3.22Å; F100-Y252 AromaticContact CD2-CD2 3.45Å; F100-Y252 HydrophobicContact CD2-CD2 3.45Å; F100-Y252 VanDerWaalsContact CD2-CD2 3.45Å; F100-Y252 AromaticContact CD2-CE2 3.94Å; F100-Y252 HydrophobicContact CD2-CE2 3.94Å; F100-Y252 AromaticContact CE2-CD2 3.38Å; F100-Y252 HydrophobicContact CE2-CD2 3.38Å; F100-Y252 AromaticContact CE2-CE2 3.82Å; F100-Y252 HydrophobicContact CE2-CE2 3.82Å; F100-Y252 HydrophobicContact CE2-CG 4.32Å; F100-Y252 HydrophobicContact CG-CD2 4.2Å; F100-Y252 HydrophobicContact CZ-CD2 4.1Å
101D91.7Very high83.3Confident43 Ų4397.1 Ų97.123%0.2348%0.48CS..  trans-136.4111.5175.4-175.2-23.4000108.8R103 K104 N105D101-R103 PolarHBondContact O-N 2.84Å; D101-R103 VanDerWaalsContact O-N 3.12Å; D101-R103 WeakPolarHBondContact OD1-CB 3.36Å; D101-R103 IonicContact OD1-CZ 3.23Å; D101-R103 PolarHBondContact OD1-N 2.81Å; D101-R103 IonicContact OD1-NE 3.12Å; D101-R103 PolarHBondContact OD1-NE 3.45Å; D101-R103 IonicContact OD1-NH2 3.43Å; D101-R103 PolarHBondContact OD1-NH2 2.87Å; D101-R103 IonicContact OD2-CZ 3.94Å; D101-R103 IonicContact OD2-NE 3.02Å; D101-R103 PolarHBondContact OD2-NE 3.28Å; D101-R103 IonicContact OD2-NH2 2.63Å; D101-R103 PolarHBondContact OD2-NH2 2.87Å; D101-K104 HydrophobicContact CB-CB 4.27Å; D101-K104 HydrophobicContact CB-CD 4.08Å; D101-K104 HydrophobicContact CB-CG 4.06Å; D101-K104 PolarHBondContact O-N 3.3Å; D101-N105 PolarHBondContact O-N 3.16Å
102S95Very high86.1Confident14 Ų1494.6 Ų94.610%0.09846%0.461CS..Hα-helixtrans-55-32.5-178.6-54.40000112.8K104 N105 W106S102-K104 VanDerWaalsContact C-N 3.31Å; S102-K104 PolarHBondContact O-N 2.94Å; S102-N105 PolarHBondContact O-N 3.12Å; S102-W106 VanDerWaalsContact O-CE3 3.31Å; S102-W106 PolarHBondContact O-N 3.36Å
103R94.7Very high88.7Confident117 Ų11791.7 Ų91.744%0.44244%0.439SS..Hα-helixtrans-69.7-30.3179.7-59.8163.8-65.3-168.22112.4D101 K110 I113 S114D101-R103 PolarHBondContact O-N 2.84Å; D101-R103 VanDerWaalsContact O-N 3.12Å; D101-R103 WeakPolarHBondContact OD1-CB 3.36Å; D101-R103 IonicContact OD1-CZ 3.23Å; D101-R103 PolarHBondContact OD1-N 2.81Å; D101-R103 IonicContact OD1-NE 3.12Å; D101-R103 PolarHBondContact OD1-NE 3.45Å; D101-R103 IonicContact OD1-NH2 3.43Å; D101-R103 PolarHBondContact OD1-NH2 2.87Å; D101-R103 IonicContact OD2-CZ 3.94Å; D101-R103 IonicContact OD2-NE 3.02Å; D101-R103 PolarHBondContact OD2-NE 3.28Å; D101-R103 IonicContact OD2-NH2 2.63Å; D101-R103 PolarHBondContact OD2-NH2 2.87Å; R103-K110 HydrophobicContact CB-CG 4.37Å; R103-I113 HydrophobicContact CG-CB 4.08Å; R103-I113 HydrophobicContact CG-CG2 3.51Å; R103-S114 WeakPolarHBondContact CD-OG 3.12Å
104K94.6Very high91Very high169 Ų16983.1 Ų83.174%0.73541%0.413SS*.Hα-helixtrans-81.3-34.7175.1-63.1-176.9-175.4175.50111.2D101 S102D101-K104 HydrophobicContact CB-CB 4.27Å; D101-K104 HydrophobicContact CB-CD 4.08Å; D101-K104 HydrophobicContact CB-CG 4.06Å; D101-K104 PolarHBondContact O-N 3.3Å; S102-K104 VanDerWaalsContact C-N 3.31Å; S102-K104 PolarHBondContact O-N 2.94Å
105N94.2Very high92.5Very high73 Ų7384 Ų8439%0.3942%0.416SS..Hα-helixtrans-74.2-35.6-179.1-160.560.7000112.9F100 D101 S102 P107F100-N105 HydrophobicContact CE2-CB 3.62Å; F100-N105 VanDerWaalsContact CE2-CG 3.44Å; F100-N105 HydrophobicContact CZ-CB 3.63Å; D101-N105 PolarHBondContact O-N 3.16Å; S102-N105 PolarHBondContact O-N 3.12Å; N105-P107 VanDerWaalsContact C-CD 3.48Å; N105-P107 WeakPolarHBondContact O-CD 3.26Å
106W95.3Very high93.2Very high41 Ų4182.5 Ų82.516%0.15541%0.412CS..  trans-120.872.9176.4-61.4-77.8000111.1F100 S102 V108 C109 K110 I113 I140 I251 Y252F100-W106 HydrophobicContact CE1-CH2 4.21Å; F100-W106 AromaticContact CE1-CZ3 3.85Å; F100-W106 HydrophobicContact CE1-CZ3 3.85Å; F100-W106 HydrophobicContact CZ-CE3 4.45Å; F100-W106 AromaticContact CZ-CH2 3.63Å; F100-W106 HydrophobicContact CZ-CH2 3.63Å; F100-W106 AromaticContact CZ-CZ3 3.5Å; F100-W106 HydrophobicContact CZ-CZ3 3.5Å; S102-W106 VanDerWaalsContact O-CE3 3.31Å; S102-W106 PolarHBondContact O-N 3.36Å; W106-V108 PolarHBondContact O-N 3.19Å; W106-C109 HydrophobicContact CB-CB 4.18Å; W106-C109 CarbonylContact O-C 3.56Å; W106-C109 PolarHBondContact O-N 2.81Å; W106-K110 PolarHBondContact O-N 3.37Å; W106-I113 HydrophobicContact CB-CD1 4.2Å; W106-I140 HydrophobicContact CB-CG1 4.17Å; W106-I140 HydrophobicContact CD2-CD1 3.88Å; W106-I140 HydrophobicContact CD2-CG1 3.87Å; W106-I140 HydrophobicContact CD2-CG2 4.07Å; W106-I140 HydrophobicContact CE3-CD1 3.71Å; W106-I140 HydrophobicContact CE3-CG1 4.2Å; W106-I140 HydrophobicContact CG-CD1 4.34Å; W106-I140 HydrophobicContact CG-CG1 3.83Å; W106-I140 HydrophobicContact CG-CG2 4.26Å; W106-I140 HydrophobicContact CZ2-CG2 4.04Å; W106-I140 HydrophobicContact CZ3-CD1 4.1Å; W106-I251 WeakPolarHBondContact CH2-O 3.26Å; W106-Y252 VanDerWaalsContact CH2-O 3.24Å; W106-Y252 WeakPolarHBondContact CH2-O 3.27Å
107P95Very high93.7Very high87 Ų8781.2 Ų81.257%0.56541%0.405SS*.G310 helixtrans-61.8-29.5-174.824.2-34000113.3N105 C109 K110N105-P107 VanDerWaalsContact C-CD 3.48Å; N105-P107 WeakPolarHBondContact O-CD 3.26Å; P107-C109 PolarHBondContact O-N 2.87Å; P107-K110 WeakPolarHBondContact O-CB 3.34Å; P107-K110 PolarHBondContact O-N 2.9Å
108V95.3Very high93.9Very high102 Ų10281.8 Ų81.862%0.61841%0.405SS*.G310 helixtrans-65.4-28.3175.3-175.70000111.8W106W106-V108 PolarHBondContact O-N 3.19Å
109C96.6Very high94.1Very high3 Ų374.5 Ų74.52%0.0237%0.371CS..G310 helixtrans-998.4178.1-660000113.3W106 P107 D111 I112 I113 C139 I140W106-C109 HydrophobicContact CB-CB 4.18Å; W106-C109 CarbonylContact O-C 3.56Å; W106-C109 PolarHBondContact O-N 2.81Å; P107-C109 PolarHBondContact O-N 2.87Å; C109-D111 VanDerWaalsContact C-N 3.26Å; C109-D111 PolarHBondContact O-N 2.62Å; C109-I112 PolarHBondContact O-N 3.28Å; C109-I112 VanDerWaalsContact O-N 3.14Å; C109-I113 HydrophobicContact CB-CD1 3.79Å; C109-I113 HydrophobicContact CB-CG1 4.22Å; C109-I113 VanDerWaalsContact O-CG1 3.3Å; C109-I113 WeakPolarHBondContact O-CG1 2.97Å; C109-I113 PolarHBondContact O-N 3.45Å; C109-C139 WeakPolarHBondContact CA-SG 3.48Å; C109-C139 HydrophobicContact CB-CB 3.85Å; C109-C139 WeakPolarHBondContact CB-SG 3.41Å; C109-C139 WeakPolarHBondContact SG-CB 3.44Å; C109-C139 PolarHBondContact SG-O 2.9Å; C109-C139 VanDerWaalsContact SG-O 3.36Å; C109-C139 CovalentContact SG-SG 2.04Å; C109-C139 PolarHBondContact SG-SG 3.01Å; C109-I140 HydrophobicContact CB-CG1 4.39Å; C109-I140 PolarHBondContact SG-N 3.37Å
110K96.4Very high94.2Very high113 Ų11366.3 Ų66.349%0.49133%0.333SS..Hα-helixtrans-54.7-41.7-175177.9-177.3174.8-168.40112.5R103 W106 P107 S114R103-K110 HydrophobicContact CB-CG 4.37Å; W106-K110 PolarHBondContact O-N 3.37Å; P107-K110 WeakPolarHBondContact O-CB 3.34Å; P107-K110 PolarHBondContact O-N 2.9Å; K110-S114 WeakPolarHBondContact O-CB 3.27Å; K110-S114 PolarHBondContact O-N 2.9Å; K110-S114 PolarHBondContact O-OG 3.32Å
111D95.5Very high94.1Very high133 Ų13363.3 Ų63.371%0.71132%0.32SS*.Hα-helixtrans-72-31.6-176.6-65.5-22.9000112.4C109 H115C109-D111 VanDerWaalsContact C-N 3.26Å; C109-D111 PolarHBondContact O-N 2.62Å; D111-H115 PolarHBondContact O-N 3.3Å
112I97.1Very high94.2Very high15 Ų1561.3 Ų61.38%0.07731%0.309CS..Hα-helixtrans-71.8-52.5173-55.7-61.2000109.8C109 S114 H115 C139 A147 F149C109-I112 PolarHBondContact O-N 3.28Å; C109-I112 VanDerWaalsContact O-N 3.14Å; I112-S114 VanDerWaalsContact C-N 3.27Å; I112-S114 PolarHBondContact O-N 3.28Å; I112-H115 WeakPolarHBondContact O-CB 3.01Å; I112-H115 PolarHBondContact O-N 3.09Å; I112-H115 VanDerWaalsContact O-N 3.13Å; I112-C139 HydrophobicContact CB-CB 4.49Å; I112-C139 HydrophobicContact CG1-CB 4.34Å; I112-C139 HydrophobicContact CG2-CB 4.49Å; I112-A147 HydrophobicContact CD1-CB 4.29Å; I112-A147 HydrophobicContact CG1-CB 4.03Å; I112-F149 HydrophobicContact CD1-CD1 4.39Å; I112-F149 HydrophobicContact CD1-CE1 3.89Å; I112-F149 HydrophobicContact CD1-CE2 4.17Å; I112-F149 HydrophobicContact CD1-CZ 3.78Å; I112-F149 HydrophobicContact CG2-CD1 4.47Å; I112-F149 HydrophobicContact CG2-CE1 4.15Å
113I96.8Very high94Very high23 Ų2360.7 Ų60.712%0.11831%0.305CS..Hα-helixtrans-63.1-32.1-177.6-61.3165.6000112R103 W106 C109 D136 I140 P256R103-I113 HydrophobicContact CG-CB 4.08Å; R103-I113 HydrophobicContact CG-CG2 3.51Å; W106-I113 HydrophobicContact CB-CD1 4.2Å; C109-I113 HydrophobicContact CB-CD1 3.79Å; C109-I113 HydrophobicContact CB-CG1 4.22Å; C109-I113 VanDerWaalsContact O-CG1 3.3Å; C109-I113 WeakPolarHBondContact O-CG1 2.97Å; C109-I113 PolarHBondContact O-N 3.45Å; I113-D136 WeakPolarHBondContact CA-OD1 3.31Å; I113-D136 HydrophobicContact CG1-CB 4.18Å; I113-I140 HydrophobicContact CD1-CD1 4.05Å; I113-I140 HydrophobicContact CD1-CG1 4.29Å; I113-P256 HydrophobicContact CG2-CG 4.15Å
114S95.6Very high94Very high46 Ų4655.1 Ų55.132%0.32228%0.284SS..THydrogen-bonded Turntrans-86.3-6.9-178.9-52.50000113.5R103 K110 I112 I116R103-S114 WeakPolarHBondContact CD-OG 3.12Å; K110-S114 WeakPolarHBondContact O-CB 3.27Å; K110-S114 PolarHBondContact O-N 2.9Å; K110-S114 PolarHBondContact O-OG 3.32Å; I112-S114 VanDerWaalsContact C-N 3.27Å; I112-S114 PolarHBondContact O-N 3.28Å; S114-I116 PolarHBondContact O-N 3.21Å
115H95.2Very high94Very high68 Ų6848.2 Ų48.232%0.31526%0.257SS..  trans-75.8124.6-177.1-173.676.1000111.2D111 I112 F149D111-H115 PolarHBondContact O-N 3.3Å; I112-H115 WeakPolarHBondContact O-CB 3.01Å; I112-H115 PolarHBondContact O-N 3.09Å; I112-H115 VanDerWaalsContact O-N 3.13Å; H115-F149 HydrophobicContact CB-CE1 3.57Å; H115-F149 HydrophobicContact CB-CZ 3.67Å; H115-F149 AromaticContact CD2-CE1 3.58Å; H115-F149 AromaticContact CD2-CZ 3.77Å; H115-F149 AromaticContact CG-CE1 3.61Å; H115-F149 AromaticContact CG-CZ 3.52Å; H115-F149 AromaticContact ND1-CZ 3.97Å
116I92.5Very high94Very high149 Ų14945 Ų4576%0.76424%0.239SC*.  trans-102.4111.6178.9-53.2-56.3000108.9S114S114-I116 PolarHBondContact O-N 3.21Å
117K91.4Very high94.1Very high25 Ų2543 Ų4311%0.10923%0.232CC..  trans-77.6144.6175.8-65.2-170.8177.1-169.30111.3V128 S132 L150 E152K117-V128 HydrophobicContact CB-CG1 3.55Å; K117-V128 HydrophobicContact CD-CG1 4.32Å; K117-S132 WeakPolarHBondContact CD-OG 3.09Å; K117-L150 PolarHBondContact NZ-O 2.78Å; K117-E152 IonicContact NZ-OE1 3.52Å; K117-E152 IonicContact NZ-OE2 2.76Å; K117-E152 PolarHBondContact NZ-OE2 3.38Å
118D90.1Very high94.1Very high62 Ų6239.3 Ų39.333%0.33221%0.208SC..  trans-100.5117.4176.5-176.82.5000110.4S120 Y198 P202D118-S120 PolarHBondContact O-N 3.35Å; D118-S120 WeakPolarHBondContact OD1-CA 3.37Å; D118-S120 PolarHBondContact OD1-N 3.06Å; D118-Y198 WeakPolarHBondContact O-CE1 3.43Å; D118-P202 WeakPolarHBondContact OD2-CB 3.39Å
119Q92.3Very high94.2Very high41 Ų4137 Ų3719%0.19220%0.196CC..  trans-73.9-7.6176.367.9179.288.400113.6L65 C122 V128 Y198L65-Q119 PolarHBondContact O-NE2 3.41Å; Q119-C122 PolarHBondContact NE2-O 2.69Å; Q119-V128 HydrophobicContact CB-CG2 3.93Å; Q119-Y198 PolarHBondContact O-OH 3.15Å
120S91.5Very high94.2Very high2 Ų236.9 Ų36.91%0.01420%0.195CC..THydrogen-bonded Turntrans53.2-142.2-174.7-173.90000111.8Y53 L65 D118 C122 A201 C203Y53-S120 PolarHBondContact OH-O 3.42Å; Y53-S120 VanDerWaalsContact OH-O 3.11Å; L65-S120 WeakPolarHBondContact CD2-O 3.44Å; D118-S120 PolarHBondContact O-N 3.35Å; D118-S120 WeakPolarHBondContact OD1-CA 3.37Å; D118-S120 PolarHBondContact OD1-N 3.06Å; S120-C122 VanDerWaalsContact C-N 3.33Å; S120-C122 PolarHBondContact O-N 3.12Å; S120-A201 WeakPolarHBondContact CB-O 3.38Å; S120-A201 PolarHBondContact OG-O 3.13Å; S120-C203 PolarHBondContact OG-SG 2.89Å
121N89.7Confident94.2Very high3 Ų331.5 Ų31.52%0.01617%0.172CC..THydrogen-bonded Turntrans-96.640.7-178.6-142.250.9000113.5K57 C206 G208 S210K57-N121 PolarHBondContact NZ-OD1 2.81Å; N121-C206 HydrophobicContact CB-CB 3.64Å; N121-C206 VanDerWaalsContact CB-SG 3.58Å; N121-C206 VanDerWaalsContact CG-CB 3.42Å; N121-C206 WeakPolarHBondContact ND2-CB 3.21Å; N121-G208 PolarHBondContact ND2-O 2.83Å; N121-S210 PolarHBondContact O-N 2.62Å
122C92.5Very high94.3Very high1 Ų126.4 Ų26.41%0.00715%0.147CC..SBendtrans-123.6139.3179.7173.40000108.9Q119 S120 S124 C166 I200Q119-C122 PolarHBondContact NE2-O 2.69Å; S120-C122 VanDerWaalsContact C-N 3.33Å; S120-C122 PolarHBondContact O-N 3.12Å; C122-S124 PolarHBondContact O-N 3.27Å; C122-S124 WeakPolarHBondContact SG-CB 3.17Å; C122-C166 HydrophobicContact CB-CB 4Å; C122-C166 WeakPolarHBondContact CB-SG 3.38Å; C122-C166 WeakPolarHBondContact SG-CA 3.29Å; C122-C166 WeakPolarHBondContact SG-CB 3.25Å; C122-C166 CovalentContact SG-SG 2.03Å; C122-C166 PolarHBondContact SG-SG 3.3Å; C122-I200 HydrophobicContact CB-CD1 3.51Å
123G92.4Very high94.4Very high1 Ų126 Ų261%0.0115%0.145CC..SBendtrans-72.950.1171.700000112N64 G67 W126 C166N64-G123 WeakPolarHBondContact O-CA 3.34Å; N64-G123 PolarHBondContact O-N 2.92Å; G67-G123 WeakPolarHBondContact CA-O 3.29Å; G123-W126 VanDerWaalsContact O-CD1 3.29Å; G123-W126 PolarHBondContact O-NE1 3.32Å; G123-C166 WeakPolarHBondContact CA-O 3.24Å; G123-C166 PolarHBondContact N-O 3.09Å
124S94.6Very high94.4Very high0 Ų025 Ų250%014%0.139CC..  trans-101.111.8-175.4540000113.8C122 W126 A127 V128 Y198C122-S124 PolarHBondContact O-N 3.27Å; C122-S124 WeakPolarHBondContact SG-CB 3.17Å; S124-W126 PolarHBondContact O-N 3.31Å; S124-W126 VanDerWaalsContact O-N 3.08Å; S124-A127 WeakPolarHBondContact O-CA 3.27Å; S124-A127 WeakPolarHBondContact O-CB 3.28Å; S124-A127 PolarHBondContact O-N 2.59Å; S124-V128 WeakPolarHBondContact O-CG2 3.47Å; S124-V128 PolarHBondContact O-N 2.98Å; S124-Y198 PolarHBondContact OG-OH 2.65Å
125C94.1Very high94.5Very high25 Ų2522.8 Ų22.817%0.16912%0.124CC..Hα-helixtrans-51.2-38.3-179.163.10000112.8G67 A127 V128 S129G67-C125 PolarHBondContact N-SG 3.38Å; G67-C125 VanDerWaalsContact N-SG 3.44Å; C125-A127 VanDerWaalsContact C-N 3.3Å; C125-A127 PolarHBondContact O-N 3.37Å; C125-V128 PolarHBondContact O-N 2.98Å; C125-S129 VanDerWaalsContact O-CB 3.29Å; C125-S129 WeakPolarHBondContact O-CB 3.35Å; C125-S129 PolarHBondContact O-N 3.4Å; C125-S129 PolarHBondContact O-OG 3.27Å; C125-S129 VanDerWaalsContact O-OG 3.09Å
126W94.3Very high94.6Very high4 Ų420.2 Ų20.22%0.01511%0.113CC..Hα-helixtrans-58.5-38.1175.566.2-89.8000113.3G123 S124 A130 L155 I156 C162 G165 G168 G169 P171 A174G123-W126 VanDerWaalsContact O-CD1 3.29Å; G123-W126 PolarHBondContact O-NE1 3.32Å; S124-W126 PolarHBondContact O-N 3.31Å; S124-W126 VanDerWaalsContact O-N 3.08Å; W126-A130 WeakPolarHBondContact O-CB 3.42Å; W126-A130 PolarHBondContact O-N 2.95Å; W126-L155 HydrophobicContact CH2-CB 4.46Å; W126-L155 HydrophobicContact CZ3-CB 4.3Å; W126-I156 HydrophobicContact CZ2-CG1 4.44Å; W126-C162 HydrophobicContact CE3-CB 4.2Å; W126-C162 HydrophobicContact CH2-CB 3.55Å; W126-C162 HydrophobicContact CZ3-CB 3.28Å; W126-G165 PolarHBondContact NE1-O 3.31Å; W126-G168 VanDerWaalsContact NE1-C 3.28Å; W126-G169 VanDerWaalsContact CB-O 3.26Å; W126-G169 WeakPolarHBondContact CB-O 3.21Å; W126-P171 HydrophobicContact CB-CG 3.95Å; W126-A174 HydrophobicContact CZ3-CB 4.45Å
127A96.4Very high94.8Very high0 Ų013.3 Ų13.30%08%0.077CC..Hα-helixtrans-84.3-42.3-179.800000111.6S124 C125 A130 A131 L155 I156S124-A127 WeakPolarHBondContact O-CA 3.27Å; S124-A127 WeakPolarHBondContact O-CB 3.28Å; S124-A127 PolarHBondContact O-N 2.59Å; C125-A127 VanDerWaalsContact C-N 3.3Å; C125-A127 PolarHBondContact O-N 3.37Å; A127-A130 PolarHBondContact O-N 3.3Å; A127-A131 VanDerWaalsContact O-CB 3.27Å; A127-A131 WeakPolarHBondContact O-CB 3.39Å; A127-A131 PolarHBondContact O-N 3.06Å; A127-L155 HydrophobicContact CB-CB 3.97Å; A127-L155 HydrophobicContact CB-CD1 4.45Å; A127-I156 HydrophobicContact CB-CD1 4.09Å; A127-I156 HydrophobicContact CB-CG1 3.47Å; A127-I156 VanDerWaalsContact CB-CG1 3.47Å
128V96.4Very high94.9Very high10 Ų1012.5 Ų12.56%0.0617%0.074CC..Hα-helixtrans-63.1-48.8179.9174.30000110.3K117 Q119 S124 C125 A130 A131 S132 E152K117-V128 HydrophobicContact CB-CG1 3.55Å; K117-V128 HydrophobicContact CD-CG1 4.32Å; Q119-V128 HydrophobicContact CB-CG2 3.93Å; S124-V128 WeakPolarHBondContact O-CG2 3.47Å; S124-V128 PolarHBondContact O-N 2.98Å; C125-V128 PolarHBondContact O-N 2.98Å; V128-A130 PolarHBondContact O-N 3.08Å; V128-A131 PolarHBondContact O-N 2.83Å; V128-S132 PolarHBondContact O-N 2.69Å; V128-S132 PolarHBondContact O-OG 3.05Å; V128-S132 VanDerWaalsContact O-OG 3.13Å; V128-E152 HydrophobicContact CG2-CB 4.21Å; V128-E152 HydrophobicContact CG2-CG 4.25Å
129S96.1Very high95.2Very high54 Ų549.5 Ų9.538%0.3786%0.058SC..Hα-helixtrans-64.5-40.6176.7-60.90000112.2C125 S132 V133 V258C125-S129 VanDerWaalsContact O-CB 3.29Å; C125-S129 WeakPolarHBondContact O-CB 3.35Å; C125-S129 PolarHBondContact O-N 3.4Å; C125-S129 PolarHBondContact O-OG 3.27Å; C125-S129 VanDerWaalsContact O-OG 3.09Å; S129-S132 PolarHBondContact O-N 3.43Å; S129-V133 WeakPolarHBondContact O-CG2 3.32Å; S129-V133 PolarHBondContact O-N 3.2Å; S129-V133 VanDerWaalsContact O-N 3.08Å; S129-V258 WeakPolarHBondContact O-CG2 3.1Å
130A96.7Very high95.2Very high0 Ų08.4 Ų8.40%05%0.053CC..Hα-helixtrans-62.4-49.4176.400000111.4W126 A127 V128 S132 V133 M134 L155 A174 F175 V258W126-A130 WeakPolarHBondContact O-CB 3.42Å; W126-A130 PolarHBondContact O-N 2.95Å; A127-A130 PolarHBondContact O-N 3.3Å; V128-A130 PolarHBondContact O-N 3.08Å; A130-S132 VanDerWaalsContact C-N 3.33Å; A130-S132 PolarHBondContact O-N 3.16Å; A130-V133 PolarHBondContact O-N 2.57Å; A130-M134 HydrophobicContact CB-CE 4.04Å; A130-M134 WeakPolarHBondContact O-CG 3.46Å; A130-M134 PolarHBondContact O-N 2.95Å; A130-L155 HydrophobicContact CB-CD1 4.25Å; A130-A174 HydrophobicContact CB-CB 3.68Å; A130-F175 HydrophobicContact CB-CE2 4.5Å; A130-F175 HydrophobicContact CB-CZ 4.41Å; A130-V258 HydrophobicContact CB-CG2 4.42Å
131A97.8Very high95Very high0 Ų010.4 Ų10.40%07%0.07CC..Hα-helixtrans-61.2-38.3178.200000112.8A127 V128 M134 S135 E152 L155A127-A131 VanDerWaalsContact O-CB 3.27Å; A127-A131 WeakPolarHBondContact O-CB 3.39Å; A127-A131 PolarHBondContact O-N 3.06Å; V128-A131 PolarHBondContact O-N 2.83Å; A131-M134 PolarHBondContact O-N 2.84Å; A131-S135 WeakPolarHBondContact O-CB 3.38Å; A131-S135 PolarHBondContact O-N 2.86Å; A131-S135 PolarHBondContact O-OG 3.39Å; A131-E152 HydrophobicContact CB-CB 3.93Å; A131-L155 HydrophobicContact CB-CD1 4.14Å
132S97.4Very high94.9Very high26 Ų2610.7 Ų10.718%0.1827%0.072CC..Hα-helixtrans-60.4-51.3173-65.50000111.4K117 V128 S129 A130 M134 S135 D136K117-S132 WeakPolarHBondContact CD-OG 3.09Å; V128-S132 PolarHBondContact O-N 2.69Å; V128-S132 PolarHBondContact O-OG 3.05Å; V128-S132 VanDerWaalsContact O-OG 3.13Å; S129-S132 PolarHBondContact O-N 3.43Å; A130-S132 VanDerWaalsContact C-N 3.33Å; A130-S132 PolarHBondContact O-N 3.16Å; S132-M134 VanDerWaalsContact C-N 3.32Å; S132-M134 PolarHBondContact O-N 2.86Å; S132-S135 WeakPolarHBondContact O-CA 3.19Å; S132-S135 VanDerWaalsContact O-CB 3.3Å; S132-S135 WeakPolarHBondContact O-CB 2.74Å; S132-S135 PolarHBondContact O-N 2.81Å; S132-D136 VanDerWaalsContact O-CG 3.23Å; S132-D136 PolarHBondContact O-N 3.13Å
133V98Very high94.8Very high7 Ų716.7 Ų16.74%0.04211%0.105CC..Hα-helixtrans-61.5-39.3178.4167.30000112.2S129 A130 S135 D136 R137 F175 P256 V258S129-V133 WeakPolarHBondContact O-CG2 3.32Å; S129-V133 PolarHBondContact O-N 3.2Å; S129-V133 VanDerWaalsContact O-N 3.08Å; A130-V133 PolarHBondContact O-N 2.57Å; V133-S135 VanDerWaalsContact C-N 3.29Å; V133-S135 PolarHBondContact O-N 3.1Å; V133-D136 PolarHBondContact O-N 3.13Å; V133-R137 HydrophobicContact CG1-CG 4.3Å; V133-R137 WeakPolarHBondContact O-CB 3.2Å; V133-R137 VanDerWaalsContact O-CG 3.27Å; V133-R137 WeakPolarHBondContact O-CG 3.28Å; V133-R137 PolarHBondContact O-N 2.84Å; V133-F175 HydrophobicContact CB-CE1 4.41Å; V133-F175 HydrophobicContact CB-CZ 4.11Å; V133-F175 HydrophobicContact CG1-CE1 3.87Å; V133-F175 HydrophobicContact CG1-CZ 3.76Å; V133-P256 VanDerWaalsContact CG1-O 3.28Å; V133-P256 WeakPolarHBondContact CG1-O 3.28Å; V133-P256 HydrophobicContact CG2-CB 4.37Å; V133-V258 HydrophobicContact CB-CG2 4.11Å; V133-V258 HydrophobicContact CG2-CG2 3.72Å
134M97.5Very high94.7Very high0 Ų017.5 Ų17.50%011%0.113CC..Hα-helixtrans-62.2-38.9174.7-62.2167.9-174.200111.5A130 A131 S132 T138 L150 L155 A174 F175 W178 V183A130-M134 HydrophobicContact CB-CE 4.04Å; A130-M134 WeakPolarHBondContact O-CG 3.46Å; A130-M134 PolarHBondContact O-N 2.95Å; A131-M134 PolarHBondContact O-N 2.84Å; S132-M134 VanDerWaalsContact C-N 3.32Å; S132-M134 PolarHBondContact O-N 2.86Å; M134-T138 VanDerWaalsContact O-CB 3.28Å; M134-T138 WeakPolarHBondContact O-CB 3.49Å; M134-T138 PolarHBondContact O-N 3.19Å; M134-T138 PolarHBondContact O-OG1 3.38Å; M134-L150 HydrophobicContact CB-CD1 3.57Å; M134-L155 HydrophobicContact CE-CD1 4.16Å; M134-L155 HydrophobicContact SD-CD1 4.3Å; M134-A174 VanDerWaalsContact CE-C 3.49Å; M134-A174 HydrophobicContact CE-CB 4.04Å; M134-A174 VanDerWaalsContact CE-O 3.23Å; M134-A174 WeakPolarHBondContact CE-O 3.36Å; M134-F175 HydrophobicContact CE-CD1 3.86Å; M134-F175 HydrophobicContact CE-CE1 4.11Å; M134-F175 HydrophobicContact CE-CG 4.37Å; M134-F175 HydrophobicContact CG-CD1 4.21Å; M134-F175 HydrophobicContact CG-CE1 3.9Å; M134-W178 HydrophobicContact CB-CD2 4.11Å; M134-W178 HydrophobicContact CB-CE3 4.18Å; M134-W178 HydrophobicContact CB-CH2 4Å; M134-W178 HydrophobicContact CB-CZ2 3.98Å; M134-W178 HydrophobicContact CB-CZ3 4.11Å; M134-W178 HydrophobicContact CE-CB 3.72Å; M134-W178 HydrophobicContact CE-CD2 4.48Å; M134-W178 HydrophobicContact CE-CE3 4.46Å; M134-W178 HydrophobicContact CE-CG 4.24Å; M134-W178 HydrophobicContact CG-CD2 3.65Å; M134-W178 HydrophobicContact CG-CE3 3.53Å; M134-W178 HydrophobicContact CG-CG 4.17Å; M134-W178 HydrophobicContact CG-CH2 4.21Å; M134-W178 HydrophobicContact CG-CZ2 4.38Å; M134-W178 HydrophobicContact CG-CZ3 3.81Å; M134-W178 HydrophobicContact SD-CB 3.92Å; M134-W178 HydrophobicContact SD-CD2 4Å; M134-W178 HydrophobicContact SD-CE3 4.33Å; M134-W178 HydrophobicContact SD-CG 3.86Å; M134-V183 HydrophobicContact SD-CG2 4Å
135S97.4Very high94.5Very high1 Ų122.2 Ų22.21%0.00715%0.146CC..Hα-helixtrans-65.2-50.6177-51.20000110.8A131 S132 V133 R137 T138 C139 L150A131-S135 WeakPolarHBondContact O-CB 3.38Å; A131-S135 PolarHBondContact O-N 2.86Å; A131-S135 PolarHBondContact O-OG 3.39Å; S132-S135 WeakPolarHBondContact O-CA 3.19Å; S132-S135 VanDerWaalsContact O-CB 3.3Å; S132-S135 WeakPolarHBondContact O-CB 2.74Å; S132-S135 PolarHBondContact O-N 2.81Å; V133-S135 VanDerWaalsContact C-N 3.29Å; V133-S135 PolarHBondContact O-N 3.1Å; S135-R137 PolarHBondContact O-N 2.8Å; S135-T138 PolarHBondContact O-N 2.97Å; S135-C139 PolarHBondContact O-N 2.96Å; S135-L150 PolarHBondContact OG-N 3.01Å
136D97.8Very high94.4Very high14 Ų1422.6 Ų22.68%0.07515%0.148CC..Hα-helixtrans-55.5-51.3179.2-63-17.7000111I113 S132 V133 T138 C139 I140 P256I113-D136 WeakPolarHBondContact CA-OD1 3.31Å; I113-D136 HydrophobicContact CG1-CB 4.18Å; S132-D136 VanDerWaalsContact O-CG 3.23Å; S132-D136 PolarHBondContact O-N 3.13Å; V133-D136 PolarHBondContact O-N 3.13Å; D136-T138 VanDerWaalsContact C-N 3.32Å; D136-T138 PolarHBondContact O-N 3.35Å; D136-C139 WeakPolarHBondContact O-CB 3.48Å; D136-C139 PolarHBondContact O-N 3.28Å; D136-I140 VanDerWaalsContact O-CG1 3.27Å; D136-I140 WeakPolarHBondContact O-CG1 3.21Å; D136-I140 PolarHBondContact O-N 3.24Å; D136-P256 HydrophobicContact CB-CG 4.15Å; D136-P256 WeakPolarHBondContact OD2-CG 3.43Å
137R96.2Very high94.3Very high3 Ų324.8 Ų24.81%0.01117%0.166CC..Hα-helixtrans-70.6-28.2-177.6-66.5-169.6169.6-144.3-14.8113V133 S135 A141 Y238 D250 Y254 G255 P256 A292 G293 A295V133-R137 HydrophobicContact CG1-CG 4.3Å; V133-R137 WeakPolarHBondContact O-CB 3.2Å; V133-R137 VanDerWaalsContact O-CG 3.27Å; V133-R137 WeakPolarHBondContact O-CG 3.28Å; V133-R137 PolarHBondContact O-N 2.84Å; S135-R137 PolarHBondContact O-N 2.8Å; R137-A141 WeakPolarHBondContact O-CB 3.33Å; R137-A141 PolarHBondContact O-N 3.47Å; R137-Y238 PolarHBondContact NH1-OH 3.14Å; R137-D250 IonicContact CZ-OD2 3.91Å; R137-D250 IonicContact NH1-OD2 2.9Å; R137-D250 PolarHBondContact NH1-OD2 2.9Å; R137-D250 IonicContact NH2-OD2 2.77Å; R137-D250 PolarHBondContact NH2-OD2 3.15Å; R137-Y254 WeakPolarHBondContact CG-O 3.3Å; R137-G255 PolarHBondContact NH2-O 2.97Å; R137-P256 PolarHBondContact NE-O 2.9Å; R137-P256 PolarHBondContact NH2-O 3.3Å; R137-A292 VanDerWaalsContact CZ-CB 3.49Å; R137-A292 VanDerWaalsContact NH1-CB 3.31Å; R137-G293 WeakPolarHBondContact CD-O 2.98Å; R137-G293 PolarHBondContact NH1-O 2.91Å; R137-A295 HydrophobicContact CB-CB 4.47Å; R137-A295 WeakPolarHBondContact O-CB 3.41Å
138T94.4Very high94.2Very high8 Ų826.8 Ų26.85%0.04918%0.178CC..Hα-helixtrans-67.3-43.5172.1-60.90000110.9M134 S135 D136 S142 T146 W178 A295M134-T138 VanDerWaalsContact O-CB 3.28Å; M134-T138 WeakPolarHBondContact O-CB 3.49Å; M134-T138 PolarHBondContact O-N 3.19Å; M134-T138 PolarHBondContact O-OG1 3.38Å; S135-T138 PolarHBondContact O-N 2.97Å; D136-T138 VanDerWaalsContact C-N 3.32Å; D136-T138 PolarHBondContact O-N 3.35Å; T138-S142 VanDerWaalsContact O-CB 3.25Å; T138-S142 WeakPolarHBondContact O-CB 3.42Å; T138-S142 PolarHBondContact O-N 2.87Å; T138-S142 PolarHBondContact O-OG 3.22Å; T138-T146 HydrophobicContact CG2-CG2 3.64Å; T138-W178 WeakPolarHBondContact OG1-CZ2 3.24Å; T138-A295 VanDerWaalsContact CA-CB 3.46Å
139C95Very high94.3Very high0 Ų028.9 Ų28.90%019%0.187CC..Hα-helixtrans-62.6-50173.5-173.60000111.4C109 I112 S135 D136 S142 N143 G144 T146C109-C139 WeakPolarHBondContact CA-SG 3.48Å; C109-C139 HydrophobicContact CB-CB 3.85Å; C109-C139 WeakPolarHBondContact CB-SG 3.41Å; C109-C139 WeakPolarHBondContact SG-CB 3.44Å; C109-C139 PolarHBondContact SG-O 2.9Å; C109-C139 VanDerWaalsContact SG-O 3.36Å; C109-C139 CovalentContact SG-SG 2.04Å; C109-C139 PolarHBondContact SG-SG 3.01Å; I112-C139 HydrophobicContact CB-CB 4.49Å; I112-C139 HydrophobicContact CG1-CB 4.34Å; I112-C139 HydrophobicContact CG2-CB 4.49Å; S135-C139 PolarHBondContact O-N 2.96Å; D136-C139 WeakPolarHBondContact O-CB 3.48Å; D136-C139 PolarHBondContact O-N 3.28Å; C139-S142 CarbonylContact O-C 3.59Å; C139-S142 PolarHBondContact O-N 3.13Å; C139-S142 PolarHBondContact O-OG 3.46Å; C139-S142 VanDerWaalsContact O-OG 3.05Å; C139-N143 PolarHBondContact O-N 3.31Å; C139-N143 VanDerWaalsContact O-N 3.11Å; C139-G144 PolarHBondContact O-N 3.34Å; C139-T146 WeakPolarHBondContact CA-O 3.15Å; C139-T146 PolarHBondContact N-O 3.24Å
140I92.8Very high94.3Very high17 Ų1726.3 Ų26.39%0.08717%0.169CC..Hα-helixtrans-60-51.4-178-70.6167.3000111.2W106 C109 I113 D136 S142 N143W106-I140 HydrophobicContact CB-CG1 4.17Å; W106-I140 HydrophobicContact CD2-CD1 3.88Å; W106-I140 HydrophobicContact CD2-CG1 3.87Å; W106-I140 HydrophobicContact CD2-CG2 4.07Å; W106-I140 HydrophobicContact CE3-CD1 3.71Å; W106-I140 HydrophobicContact CE3-CG1 4.2Å; W106-I140 HydrophobicContact CG-CD1 4.34Å; W106-I140 HydrophobicContact CG-CG1 3.83Å; W106-I140 HydrophobicContact CG-CG2 4.26Å; W106-I140 HydrophobicContact CZ2-CG2 4.04Å; W106-I140 HydrophobicContact CZ3-CD1 4.1Å; C109-I140 HydrophobicContact CB-CG1 4.39Å; C109-I140 PolarHBondContact SG-N 3.37Å; I113-I140 HydrophobicContact CD1-CD1 4.05Å; I113-I140 HydrophobicContact CD1-CG1 4.29Å; D136-I140 VanDerWaalsContact O-CG1 3.27Å; D136-I140 WeakPolarHBondContact O-CG1 3.21Å; D136-I140 PolarHBondContact O-N 3.24Å; I140-S142 PolarHBondContact O-N 2.97Å; I140-N143 PolarHBondContact O-N 2.69Å
141A87.7Confident94.4Very high44 Ų4426.3 Ų26.336%0.36417%0.169SC..Hα-helixtrans-62.9-34.2-178.100000112.2R137 N143 A295 V297R137-A141 WeakPolarHBondContact O-CB 3.33Å; R137-A141 PolarHBondContact O-N 3.47Å; A141-N143 VanDerWaalsContact C-N 3.27Å; A141-N143 PolarHBondContact O-N 3.48Å; A141-A295 HydrophobicContact CB-CB 3.96Å; A141-V297 HydrophobicContact CB-CG2 3.68Å; A141-V297 WeakPolarHBondContact O-CG2 3.44Å
142S87.2Confident94.3Very high9 Ų926.6 Ų26.66%0.06317%0.17CC..THydrogen-bonded Turntrans-864.7178.670.60000113.7T138 C139 I140 G144 S145 T146T138-S142 VanDerWaalsContact O-CB 3.25Å; T138-S142 WeakPolarHBondContact O-CB 3.42Å; T138-S142 PolarHBondContact O-N 2.87Å; T138-S142 PolarHBondContact O-OG 3.22Å; C139-S142 CarbonylContact O-C 3.59Å; C139-S142 PolarHBondContact O-N 3.13Å; C139-S142 PolarHBondContact O-OG 3.46Å; C139-S142 VanDerWaalsContact O-OG 3.05Å; I140-S142 PolarHBondContact O-N 2.97Å; S142-G144 PolarHBondContact O-N 2.8Å; S142-S145 WeakPolarHBondContact CB-OG 3.05Å; S142-S145 WeakPolarHBondContact O-CB 3.11Å; S142-S145 PolarHBondContact O-N 3.36Å; S142-S145 VanDerWaalsContact O-N 3.08Å; S142-S145 PolarHBondContact O-OG 2.79Å; S142-T146 WeakPolarHBondContact OG-CA 3.16Å; S142-T146 WeakPolarHBondContact OG-CB 3.37Å; S142-T146 PolarHBondContact OG-N 2.82Å
143N90.3Very high94.3Very high128 Ų12826 Ų2668%0.68417%0.165SC*.THydrogen-bonded Turntrans49.640.8-173.6-164.236000113C139 I140 A141 S145C139-N143 PolarHBondContact O-N 3.31Å; C139-N143 VanDerWaalsContact O-N 3.11Å; I140-N143 PolarHBondContact O-N 2.69Å; A141-N143 VanDerWaalsContact C-N 3.27Å; A141-N143 PolarHBondContact O-N 3.48Å; N143-S145 VanDerWaalsContact C-N 3.33Å; N143-S145 PolarHBondContact O-N 2.88Å
144G90.3Very high94.2Very high18 Ų1825.8 Ų25.819%0.18616%0.163CC..THydrogen-bonded Turntrans84.8-10.2179.900000116.2C139 S142 T146C139-G144 PolarHBondContact O-N 3.34Å; S142-G144 PolarHBondContact O-N 2.8Å; G144-T146 PolarHBondContact O-N 2.79Å
145S90.6Very high94.2Very high98 Ų9825.8 Ų25.869%0.68516%0.163SC*.THydrogen-bonded Turntrans-66.4-22.4178.762.90000113.3S142 N143S142-S145 WeakPolarHBondContact CB-OG 3.05Å; S142-S145 WeakPolarHBondContact O-CB 3.11Å; S142-S145 PolarHBondContact O-N 3.36Å; S142-S145 VanDerWaalsContact O-N 3.08Å; S142-S145 PolarHBondContact O-OG 2.79Å; N143-S145 VanDerWaalsContact C-N 3.33Å; N143-S145 PolarHBondContact O-N 2.88Å
146T91.7Very high94.1Very high34 Ų3426 Ų2621%0.20916%0.164CC..THydrogen-bonded Turntrans-122.673.2172.5-50.80000109.9T138 C139 S142 G144 V148T138-T146 HydrophobicContact CG2-CG2 3.64Å; C139-T146 WeakPolarHBondContact CA-O 3.15Å; C139-T146 PolarHBondContact N-O 3.24Å; S142-T146 WeakPolarHBondContact OG-CA 3.16Å; S142-T146 WeakPolarHBondContact OG-CB 3.37Å; S142-T146 PolarHBondContact OG-N 2.82Å; G144-T146 PolarHBondContact O-N 2.79Å; T146-V148 HydrophobicContact CG2-CG2 4.04Å; T146-V148 PolarHBondContact O-N 2.66Å
147A93.2Very high94Very high49 Ų4925.9 Ų25.941%0.40516%0.164SC..  trans-93.276.7176.400000111.1I112I112-A147 HydrophobicContact CD1-CB 4.29Å; I112-A147 HydrophobicContact CG1-CB 4.03Å
148V94.6Very high93.8Very high43 Ų4326.5 Ų26.526%0.26117%0.169SC..  trans-126150.7-179-59.80000111.5T146 L150 T185T146-V148 HydrophobicContact CG2-CG2 4.04Å; T146-V148 PolarHBondContact O-N 2.66Å; V148-L150 HydrophobicContact CG2-CD2 4.19Å; V148-T185 HydrophobicContact CB-CG2 4.02Å; V148-T185 HydrophobicContact CG1-CG2 4.39Å; V148-T185 HydrophobicContact CG2-CG2 4.03Å
149F97.2Very high93.4Very high54 Ų5426.4 Ų26.424%0.23717%0.168CC..  trans-83.9131.5169.7-64.3-64.6000110I112 H115 T185 G186I112-F149 HydrophobicContact CD1-CD1 4.39Å; I112-F149 HydrophobicContact CD1-CE1 3.89Å; I112-F149 HydrophobicContact CD1-CE2 4.17Å; I112-F149 HydrophobicContact CD1-CZ 3.78Å; I112-F149 HydrophobicContact CG2-CD1 4.47Å; I112-F149 HydrophobicContact CG2-CE1 4.15Å; H115-F149 HydrophobicContact CB-CE1 3.57Å; H115-F149 HydrophobicContact CB-CZ 3.67Å; H115-F149 AromaticContact CD2-CE1 3.58Å; H115-F149 AromaticContact CD2-CZ 3.77Å; H115-F149 AromaticContact CG-CE1 3.61Å; H115-F149 AromaticContact CG-CZ 3.52Å; H115-F149 AromaticContact ND1-CZ 3.97Å; F149-T185 CarbonylContact O-C 3.55Å; F149-T185 VanDerWaalsContact O-CA 3.22Å; F149-T185 WeakPolarHBondContact O-CA 3.34Å; F149-G186 WeakPolarHBondContact CB-O 3.28Å; F149-G186 PolarHBondContact O-N 2.85Å; F149-G186 VanDerWaalsContact O-O 3.11Å
150L97.3Very high92.8Very high0 Ų036.9 Ų36.90%021%0.208CC..BIsolated β-bridgetrans-93.1151.3175.6-61.7-178000111.1K117 M134 S135 V148 E152 W178 V183 H232K117-L150 PolarHBondContact NZ-O 2.78Å; M134-L150 HydrophobicContact CB-CD1 3.57Å; S135-L150 PolarHBondContact OG-N 3.01Å; V148-L150 HydrophobicContact CG2-CD2 4.19Å; L150-E152 PolarHBondContact O-N 2.98Å; L150-W178 HydrophobicContact CD1-CZ2 4.27Å; L150-V183 HydrophobicContact CB-CG1 3.99Å; L150-H232 HydrophobicContact CD1-CB 4.23Å; L150-H232 HydrophobicContact CD2-CB 3.74Å
151S97.4Very high91.9Very high0 Ų039.2 Ų39.20%022%0.22CC..  trans-82.7110.3-166.1-177.50000114.5E153 E154 V183 P184 K196S151-E153 VanDerWaalsContact C-N 3.27Å; S151-E153 WeakPolarHBondContact OG-CB 3.38Å; S151-E153 PolarHBondContact OG-N 2.99Å; S151-E154 PolarHBondContact O-N 3.34Å; S151-E154 PolarHBondContact OG-N 3.2Å; S151-V183 WeakPolarHBondContact O-CG1 3.35Å; S151-P184 WeakPolarHBondContact CB-O 3.49Å; S151-P184 PolarHBondContact N-O 2.91Å; S151-K196 WeakPolarHBondContact CB-O 3.17Å; S151-K196 WeakPolarHBondContact OG-CB 3.34Å; S151-K196 PolarHBondContact OG-O 3.3Å
152E96.9Very high91.5Very high5 Ų537.1 Ų37.12%0.02320%0.203CC..Hα-helixtrans-64-31.9163.458.9-86-155.700111.9K117 V128 A131 L150 E154 L155 I156 Y198K117-E152 IonicContact NZ-OE1 3.52Å; K117-E152 IonicContact NZ-OE2 2.76Å; K117-E152 PolarHBondContact NZ-OE2 3.38Å; V128-E152 HydrophobicContact CG2-CB 4.21Å; V128-E152 HydrophobicContact CG2-CG 4.25Å; A131-E152 HydrophobicContact CB-CB 3.93Å; L150-E152 PolarHBondContact O-N 2.98Å; E152-E154 VanDerWaalsContact C-N 3.35Å; E152-E154 PolarHBondContact O-N 2.97Å; E152-L155 PolarHBondContact O-N 3.19Å; E152-L155 VanDerWaalsContact O-N 3.13Å; E152-I156 HydrophobicContact CB-CD1 4.31Å; E152-I156 WeakPolarHBondContact O-CB 3.27Å; E152-I156 WeakPolarHBondContact O-CD1 3.1Å; E152-I156 WeakPolarHBondContact O-CG1 3.24Å; E152-I156 PolarHBondContact O-N 2.96Å; E152-Y198 HydrophobicContact CG-CD2 3.53Å; E152-Y198 HydrophobicContact CG-CE2 4Å; E152-Y198 HydrophobicContact CG-CG 4.17Å
153E96.6Very high91Very high15 Ų1538.3 Ų38.37%0.0722%0.216CC..Hα-helixtrans-60.6-42.2176179.268.6-151.600111.4S151 L155 I156 S157 S199 P213S151-E153 VanDerWaalsContact C-N 3.27Å; S151-E153 WeakPolarHBondContact OG-CB 3.38Å; S151-E153 PolarHBondContact OG-N 2.99Å; E153-L155 VanDerWaalsContact C-N 3.34Å; E153-L155 PolarHBondContact O-N 3.43Å; E153-I156 PolarHBondContact O-N 2.78Å; E153-S157 VanDerWaalsContact O-CB 3.24Å; E153-S157 WeakPolarHBondContact O-CB 3.18Å; E153-S157 PolarHBondContact O-N 2.7Å; E153-S157 PolarHBondContact O-OG 3.17Å; E153-S199 VanDerWaalsContact CD-OG 3.25Å; E153-S199 PolarHBondContact OE1-OG 2.81Å; E153-S199 VanDerWaalsContact OE2-CB 3.3Å; E153-S199 WeakPolarHBondContact OE2-CB 3.46Å; E153-S199 PolarHBondContact OE2-N 3.19Å; E153-S199 PolarHBondContact OE2-OG 3.46Å; E153-P213 WeakPolarHBondContact OE1-CB 3.45Å
154E97.3Very high90.7Very high1 Ų139.1 Ų39.11%0.00522%0.218CC..Hα-helixtrans-59.7-44.5173174.576.7171.800111.3S151 E152 C158 C159 Y177 V183 P184 K196 R231S151-E154 PolarHBondContact O-N 3.34Å; S151-E154 PolarHBondContact OG-N 3.2Å; E152-E154 VanDerWaalsContact C-N 3.35Å; E152-E154 PolarHBondContact O-N 2.97Å; E154-C158 WeakPolarHBondContact O-CA 3.32Å; E154-C158 VanDerWaalsContact O-CB 3.26Å; E154-C158 WeakPolarHBondContact O-CB 3.49Å; E154-C158 PolarHBondContact O-N 3.49Å; E154-C159 PolarHBondContact O-N 3.46Å; E154-Y177 HydrophobicContact CG-CE1 3.93Å; E154-Y177 PolarHBondContact OE1-OH 3.26Å; E154-V183 HydrophobicContact CB-CG1 4.44Å; E154-P184 HydrophobicContact CB-CG 4Å; E154-P184 HydrophobicContact CG-CG 4.17Å; E154-K196 HydrophobicContact CB-CD 4.19Å; E154-K196 WeakPolarHBondContact OE2-CD 3.48Å; E154-K196 WeakPolarHBondContact OE2-CE 3.37Å; E154-K196 IonicContact OE2-NZ 2.88Å; E154-K196 PolarHBondContact OE2-NZ 3.03Å; E154-R231 IonicContact OE1-CZ 2.64Å; E154-R231 VanDerWaalsContact OE1-CZ 3.32Å; E154-R231 IonicContact OE1-NH1 3.54Å; E154-R231 PolarHBondContact OE1-NH1 3.21Å; E154-R231 IonicContact OE1-NH2 2.66Å; E154-R231 PolarHBondContact OE1-NH2 3.4Å; E154-R231 IonicContact OE2-NH2 3.74Å
155L96.8Very high90.7Very high0 Ų038.4 Ų38.40%021%0.21CC..Hα-helixtrans-65.5-47.1-179.3-64.6177.5000111W126 A127 A130 A131 M134 E152 E153 C159 A174 Y177 V183W126-L155 HydrophobicContact CH2-CB 4.46Å; W126-L155 HydrophobicContact CZ3-CB 4.3Å; A127-L155 HydrophobicContact CB-CB 3.97Å; A127-L155 HydrophobicContact CB-CD1 4.45Å; A130-L155 HydrophobicContact CB-CD1 4.25Å; A131-L155 HydrophobicContact CB-CD1 4.14Å; M134-L155 HydrophobicContact CE-CD1 4.16Å; M134-L155 HydrophobicContact SD-CD1 4.3Å; E152-L155 PolarHBondContact O-N 3.19Å; E152-L155 VanDerWaalsContact O-N 3.13Å; E153-L155 VanDerWaalsContact C-N 3.34Å; E153-L155 PolarHBondContact O-N 3.43Å; L155-C159 WeakPolarHBondContact O-CB 3.3Å; L155-C159 PolarHBondContact O-N 2.91Å; L155-A174 HydrophobicContact CD1-CB 4.17Å; L155-A174 HydrophobicContact CD2-CB 4.29Å; L155-Y177 HydrophobicContact CD2-CD1 3.81Å; L155-Y177 HydrophobicContact CD2-CE1 4.44Å; L155-Y177 HydrophobicContact CD2-CG 4.44Å; L155-V183 HydrophobicContact CD2-CG2 3.95Å
156I95.3Very high90.8Very high7 Ų734.1 Ų34.14%0.03618%0.18CC..Hα-helixtrans-66.8-45.5-177.2-65.1159.8000111.2W126 A127 E152 E153 Y198 T212W126-I156 HydrophobicContact CZ2-CG1 4.44Å; A127-I156 HydrophobicContact CB-CD1 4.09Å; A127-I156 HydrophobicContact CB-CG1 3.47Å; A127-I156 VanDerWaalsContact CB-CG1 3.47Å; E152-I156 HydrophobicContact CB-CD1 4.31Å; E152-I156 WeakPolarHBondContact O-CB 3.27Å; E152-I156 WeakPolarHBondContact O-CD1 3.1Å; E152-I156 WeakPolarHBondContact O-CG1 3.24Å; E152-I156 PolarHBondContact O-N 2.96Å; E153-I156 PolarHBondContact O-N 2.78Å; I156-Y198 HydrophobicContact CD1-CD2 4.34Å; I156-Y198 HydrophobicContact CD1-CE2 3.52Å; I156-T212 HydrophobicContact CG2-CG2 4.21Å
157S95.2Very high90.6Very high11 Ų1138.7 Ų38.78%0.07720%0.203CC..Hα-helixtrans-87.9-36.5-170.868.90000113.3E153 P213 C215E153-S157 VanDerWaalsContact O-CB 3.24Å; E153-S157 WeakPolarHBondContact O-CB 3.18Å; E153-S157 PolarHBondContact O-N 2.7Å; E153-S157 PolarHBondContact O-OG 3.17Å; S157-P213 VanDerWaalsContact CB-O 3.23Å; S157-P213 WeakPolarHBondContact CB-O 3.42Å; S157-C215 VanDerWaalsContact O-CB 3.27Å; S157-C215 WeakPolarHBondContact O-CB 3.36Å
158C91.8Very high90.2Very high16 Ų1636.6 Ų36.611%0.10819%0.187CC..Hα-helixtrans-110.7-22.6-169.6-63.70000114.8E154 R160 K196 C215E154-C158 WeakPolarHBondContact O-CA 3.32Å; E154-C158 VanDerWaalsContact O-CB 3.26Å; E154-C158 WeakPolarHBondContact O-CB 3.49Å; E154-C158 PolarHBondContact O-N 3.49Å; C158-R160 PolarHBondContact O-N 3.01Å; C158-K196 PolarHBondContact SG-NZ 3.5Å; C158-C215 VanDerWaalsContact CA-SG 3.55Å; C158-C215 HydrophobicContact CB-CB 3.96Å; C158-C215 WeakPolarHBondContact CB-SG 3.38Å; C158-C215 WeakPolarHBondContact SG-CA 3.3Å; C158-C215 WeakPolarHBondContact SG-CB 3.16Å; C158-C215 CovalentContact SG-SG 2.04Å; C158-C215 PolarHBondContact SG-SG 3.32Å
159C86.2Confident89.8Confident5 Ų534.7 Ų34.73%0.03418%0.176CC..  trans-78.785.5-178.6-173.80000112.6E154 L155 I161 C162 Y177E154-C159 PolarHBondContact O-N 3.46Å; L155-C159 WeakPolarHBondContact O-CB 3.3Å; L155-C159 PolarHBondContact O-N 2.91Å; C159-I161 PolarHBondContact O-N 2.99Å; C159-I161 VanDerWaalsContact O-N 3.17Å; C159-I161 WeakPolarHBondContact SG-CG1 3.49Å; C159-C162 HydrophobicContact CB-CB 3.66Å; C159-C162 WeakPolarHBondContact CB-SG 3.4Å; C159-C162 PolarHBondContact O-N 3.05Å; C159-C162 WeakPolarHBondContact SG-CB 3.34Å; C159-C162 PolarHBondContact SG-N 3.07Å; C159-C162 CovalentContact SG-SG 2.01Å; C159-C162 PolarHBondContact SG-SG 3.37Å; C159-Y177 HydrophobicContact CB-CD1 4.44Å; C159-Y177 HydrophobicContact CB-CD2 3.72Å; C159-Y177 HydrophobicContact CB-CE2 3.96Å; C159-Y177 HydrophobicContact CB-CG 3.98Å; C159-Y177 VanDerWaalsContact SG-CB 3.54Å; C159-Y177 WeakPolarHBondContact SG-CD2 3.3Å; C159-Y177 VanDerWaalsContact SG-CG 3.53Å
160R82.9Confident89.2Confident220 Ų22033.3 Ų33.383%0.8317%0.169SC*.THydrogen-bonded Turntrans-61.8-22178-67.1-79.6171.5138.1-7.1114.3C158C158-R160 PolarHBondContact O-N 3.01Å
161I74Confident88.8Confident66 Ų6633.5 Ų33.534%0.33817%0.17SC..THydrogen-bonded Turntrans-88-18.4176.863.3174.5000112.4C159 R173 L176 Y177 L180C159-I161 PolarHBondContact O-N 2.99Å; C159-I161 VanDerWaalsContact O-N 3.17Å; C159-I161 WeakPolarHBondContact SG-CG1 3.49Å; I161-R173 WeakPolarHBondContact O-CD 3.09Å; I161-L176 HydrophobicContact CD1-CD2 4.04Å; I161-L176 HydrophobicContact CD1-CG 4.1Å; I161-Y177 HydrophobicContact CG1-CD2 4.48Å; I161-L180 HydrophobicContact CD1-CD1 4.34Å
162C79.3Confident88.1Confident1 Ų133.6 Ų33.61%0.00717%0.171CC..THydrogen-bonded Turntrans-80.3-32.9-171.1-640000113.3W126 C159 G169 Y170 A174W126-C162 HydrophobicContact CE3-CB 4.2Å; W126-C162 HydrophobicContact CH2-CB 3.55Å; W126-C162 HydrophobicContact CZ3-CB 3.28Å; C159-C162 HydrophobicContact CB-CB 3.66Å; C159-C162 WeakPolarHBondContact CB-SG 3.4Å; C159-C162 PolarHBondContact O-N 3.05Å; C159-C162 WeakPolarHBondContact SG-CB 3.34Å; C159-C162 PolarHBondContact SG-N 3.07Å; C159-C162 CovalentContact SG-SG 2.01Å; C159-C162 PolarHBondContact SG-SG 3.37Å; C162-G169 CarbonylContact O-C 3.4Å; C162-G169 WeakPolarHBondContact O-CA 3.18Å; C162-Y170 PolarHBondContact O-N 3.37Å; C162-A174 WeakPolarHBondContact SG-CA 3.39Å
163G76.3Confident87.5Confident34 Ų3437.5 Ų37.535%0.35119%0.186SC..BIsolated β-bridgetrans160.4-159.2-173.800000112.5G168G163-G168 CarbonylContact C-O 3.53Å
164M85Confident87.2Confident144 Ų14436.8 Ų36.871%0.70918%0.182SC*.  trans-103.932.9-178.9-59.1-170.6-158.800112.3C166 D167 G168 T212M164-C166 PolarHBondContact O-N 3.48Å; M164-D167 HydrophobicContact CB-CB 3.88Å; M164-D167 PolarHBondContact O-N 3.42Å; M164-G168 PolarHBondContact N-O 2.66Å; M164-T212 PolarHBondContact O-OG1 3.19Å
165G89.8Confident86.9Confident3 Ų336.8 Ų36.83%0.03118%0.182CC..G310 helixtrans66.2-116.6176.700000112.8W126 D167 G168W126-G165 PolarHBondContact NE1-O 3.31Å; G165-D167 VanDerWaalsContact C-N 3.26Å; G165-D167 PolarHBondContact O-N 2.97Å; G165-G168 PolarHBondContact O-N 2.73Å
166C91.5Very high86.2Confident8 Ų838.2 Ų38.25%0.05419%0.19CC..G310 helixtrans-71.8-15.2177.5-70.30000114.4C122 G123 M164 G168 S210 T212C122-C166 HydrophobicContact CB-CB 4Å; C122-C166 WeakPolarHBondContact CB-SG 3.38Å; C122-C166 WeakPolarHBondContact SG-CA 3.29Å; C122-C166 WeakPolarHBondContact SG-CB 3.25Å; C122-C166 CovalentContact SG-SG 2.03Å; C122-C166 PolarHBondContact SG-SG 3.3Å; G123-C166 WeakPolarHBondContact CA-O 3.24Å; G123-C166 PolarHBondContact N-O 3.09Å; M164-C166 PolarHBondContact O-N 3.48Å; C166-G168 PolarHBondContact O-N 2.94Å; C166-S210 WeakPolarHBondContact CB-O 3.17Å; C166-T212 PolarHBondContact N-OG1 3.48Å
167D87.3Confident85.6Confident130 Ų13038.8 Ų38.870%0.69519%0.192SC*.G310 helixtrans-875.1174.1-58.7-46.9000112.4M164 G165M164-D167 HydrophobicContact CB-CB 3.88Å; M164-D167 PolarHBondContact O-N 3.42Å; G165-D167 VanDerWaalsContact C-N 3.26Å; G165-D167 PolarHBondContact O-N 2.97Å
168G86.6Confident85.4Confident5 Ų538.3 Ų38.35%0.05219%0.188CC..  trans110.3171.5172.400000115G67 W126 G163 M164 G165 C166G67-G168 CarbonylContact O-C 3.53Å; G67-G168 WeakPolarHBondContact O-CA 3.37Å; W126-G168 VanDerWaalsContact NE1-C 3.28Å; G163-G168 CarbonylContact C-O 3.53Å; M164-G168 PolarHBondContact N-O 2.66Å; G165-G168 PolarHBondContact O-N 2.73Å; C166-G168 PolarHBondContact O-N 2.94Å
169G85.1Confident85Confident3 Ų342 Ų423%0.03120%0.2CC..BIsolated β-bridgetrans-177.4178.5-173.800000113.8G67 Y68 W126 C162G67-G169 PolarHBondContact O-N 3.31Å; Y68-G169 WeakPolarHBondContact CD2-O 3.32Å; W126-G169 VanDerWaalsContact CB-O 3.26Å; W126-G169 WeakPolarHBondContact CB-O 3.21Å; C162-G169 CarbonylContact O-C 3.4Å; C162-G169 WeakPolarHBondContact O-CA 3.18Å
170Y84.8Confident84.2Confident26 Ų2645.3 Ų45.310%0.10222%0.217CC..  trans-117.4108.1-164.2-156.8-108.9000111.2Y68 F81 C162 P172 R173 A174 R239Y68-Y170 HydrophobicContact CD2-CD2 4.44Å; Y68-Y170 AromaticContact CE2-CD2 3.57Å; Y68-Y170 HydrophobicContact CE2-CD2 3.57Å; Y68-Y170 AromaticContact CE2-CE2 3.74Å; Y68-Y170 HydrophobicContact CE2-CE2 3.74Å; Y68-Y170 HydrophobicContact CE2-CG 4.46Å; F81-Y170 HydrophobicContact CE2-CD1 4.37Å; F81-Y170 AromaticContact CE2-CE1 3.91Å; F81-Y170 HydrophobicContact CE2-CE1 3.91Å; F81-Y170 HydrophobicContact CZ-CE1 4.49Å; C162-Y170 PolarHBondContact O-N 3.37Å; Y170-P172 HydrophobicContact CD1-CB 3.87Å; Y170-P172 VanDerWaalsContact CD1-CD 3.49Å; Y170-P172 HydrophobicContact CD1-CG 3.74Å; Y170-P172 HydrophobicContact CE1-CB 3.73Å; Y170-P172 HydrophobicContact CE1-CG 3.38Å; Y170-R173 HydrophobicContact CD1-CG 4.11Å; Y170-R173 PolarHBondContact O-N 3.22Å; Y170-A174 PolarHBondContact O-N 3.48Å; Y170-R239 PolarHBondContact OH-NH1 2.85Å; Y170-R239 PolarHBondContact OH-NH2 3.42Å
171P89Confident84.1Confident4 Ų440.9 Ų40.93%0.02620%0.201CC..Hα-helixtrans-55.2-40.2-174.8-23.931.9000115.6Y68 W126 R173 A174 F175 V258Y68-P171 HydrophobicContact CD2-CG 4.25Å; Y68-P171 HydrophobicContact CE2-CG 4.18Å; W126-P171 HydrophobicContact CB-CG 3.95Å; P171-R173 PolarHBondContact O-N 2.99Å; P171-A174 WeakPolarHBondContact O-CA 3.4Å; P171-A174 VanDerWaalsContact O-CB 3.29Å; P171-A174 WeakPolarHBondContact O-CB 3.5Å; P171-A174 PolarHBondContact O-N 2.84Å; P171-F175 VanDerWaalsContact O-CD2 3.26Å; P171-F175 WeakPolarHBondContact O-CD2 3.41Å; P171-F175 PolarHBondContact O-N 2.86Å; P171-V258 HydrophobicContact CB-CB 4.44Å; P171-V258 HydrophobicContact CB-CG1 3.78Å; P171-V258 HydrophobicContact CG-CG1 4Å
172P83.7Confident84.9Confident2 Ų237.7 Ų37.71%0.01319%0.185CC..Hα-helixtrans-54.2-37.2174.3-28.835.2000113.8F81 Y170 A174 F175 L176 R239F81-P172 HydrophobicContact CD1-CB 3.77Å; F81-P172 HydrophobicContact CD2-CB 3.91Å; F81-P172 HydrophobicContact CE1-CB 3.61Å; F81-P172 WeakPolarHBondContact CE1-O 3.12Å; F81-P172 HydrophobicContact CE2-CB 3.75Å; F81-P172 HydrophobicContact CG-CB 3.94Å; F81-P172 HydrophobicContact CZ-CB 3.62Å; Y170-P172 HydrophobicContact CD1-CB 3.87Å; Y170-P172 VanDerWaalsContact CD1-CD 3.49Å; Y170-P172 HydrophobicContact CD1-CG 3.74Å; Y170-P172 HydrophobicContact CE1-CB 3.73Å; Y170-P172 HydrophobicContact CE1-CG 3.38Å; P172-A174 VanDerWaalsContact C-N 3.34Å; P172-F175 PolarHBondContact O-N 3.03Å; P172-L176 PolarHBondContact O-N 2.57Å; P172-L176 VanDerWaalsContact O-N 3.07Å; P172-R239 HydrophobicContact CG-CG 4.4Å
173R84.2Confident85.7Confident87 Ų8737.7 Ų37.733%0.32818%0.184SC..Hα-helixtrans-73-26.3177.4-70.5-174.8-171.3152.30.7112.8E80 F81 I161 Y170 P171 L176 Y177E80-R173 IonicContact OE1-CZ 2.68Å; E80-R173 IonicContact OE1-NE 3.66Å; E80-R173 PolarHBondContact OE1-NE 3.32Å; E80-R173 IonicContact OE1-NH2 2.86Å; E80-R173 PolarHBondContact OE1-NH2 3.33Å; E80-R173 VanDerWaalsContact OE1-NH2 3.11Å; E80-R173 IonicContact OE2-NH2 2.97Å; E80-R173 PolarHBondContact OE2-NH2 2.83Å; F81-R173 HydrophobicContact CE1-CG 4.34Å; F81-R173 HydrophobicContact CZ-CG 3.6Å; I161-R173 WeakPolarHBondContact O-CD 3.09Å; Y170-R173 HydrophobicContact CD1-CG 4.11Å; Y170-R173 PolarHBondContact O-N 3.22Å; P171-R173 PolarHBondContact O-N 2.99Å; R173-L176 PolarHBondContact O-N 2.96Å; R173-Y177 PolarHBondContact O-N 2.92Å
174A90.4Very high86.6Confident0 Ų036 Ų360%017%0.168CC..Hα-helixtrans-64.2-41.1169.800000111.7W126 A130 M134 L155 C162 Y170 P171 P172 Y177 W178W126-A174 HydrophobicContact CZ3-CB 4.45Å; A130-A174 HydrophobicContact CB-CB 3.68Å; M134-A174 VanDerWaalsContact CE-C 3.49Å; M134-A174 HydrophobicContact CE-CB 4.04Å; M134-A174 VanDerWaalsContact CE-O 3.23Å; M134-A174 WeakPolarHBondContact CE-O 3.36Å; L155-A174 HydrophobicContact CD1-CB 4.17Å; L155-A174 HydrophobicContact CD2-CB 4.29Å; C162-A174 WeakPolarHBondContact SG-CA 3.39Å; Y170-A174 PolarHBondContact O-N 3.48Å; P171-A174 WeakPolarHBondContact O-CA 3.4Å; P171-A174 VanDerWaalsContact O-CB 3.29Å; P171-A174 WeakPolarHBondContact O-CB 3.5Å; P171-A174 PolarHBondContact O-N 2.84Å; P172-A174 VanDerWaalsContact C-N 3.34Å; A174-Y177 WeakPolarHBondContact O-CB 3.34Å; A174-Y177 PolarHBondContact O-N 3.18Å; A174-W178 PolarHBondContact O-N 2.65Å
175F89.9Confident87.2Confident0 Ų029.5 Ų29.50%014%0.136CC..Hα-helixtrans-67.3-38.2173.8-66.4-70.3000112.5A130 V133 M134 P171 P172 Y177 W178 W179 V258 S291A130-F175 HydrophobicContact CB-CE2 4.5Å; A130-F175 HydrophobicContact CB-CZ 4.41Å; V133-F175 HydrophobicContact CB-CE1 4.41Å; V133-F175 HydrophobicContact CB-CZ 4.11Å; V133-F175 HydrophobicContact CG1-CE1 3.87Å; V133-F175 HydrophobicContact CG1-CZ 3.76Å; M134-F175 HydrophobicContact CE-CD1 3.86Å; M134-F175 HydrophobicContact CE-CE1 4.11Å; M134-F175 HydrophobicContact CE-CG 4.37Å; M134-F175 HydrophobicContact CG-CD1 4.21Å; M134-F175 HydrophobicContact CG-CE1 3.9Å; P171-F175 VanDerWaalsContact O-CD2 3.26Å; P171-F175 WeakPolarHBondContact O-CD2 3.41Å; P171-F175 PolarHBondContact O-N 2.86Å; P172-F175 PolarHBondContact O-N 3.03Å; F175-Y177 VanDerWaalsContact C-N 3.34Å; F175-Y177 PolarHBondContact O-N 3.35Å; F175-W178 AromaticContact CD1-CE3 3.97Å; F175-W178 HydrophobicContact CD1-CE3 3.97Å; F175-W178 HydrophobicContact CD1-CZ3 4.32Å; F175-W178 PolarHBondContact O-N 2.87Å; F175-W179 PolarHBondContact O-N 3.31Å; F175-V258 HydrophobicContact CE2-CB 4.23Å; F175-V258 HydrophobicContact CE2-CG2 3.86Å; F175-V258 HydrophobicContact CZ-CB 4.48Å; F175-V258 HydrophobicContact CZ-CG2 3.72Å; F175-S291 WeakPolarHBondContact CE2-O 3.48Å
176L82.8Confident87.5Confident31 Ų3129.3 Ų29.316%0.16213%0.134CC..Hα-helixtrans-59.6-43171.1173.561.3000111.7F81 I161 P172 R173 W179 L180 Y237F81-L176 HydrophobicContact CE1-CB 4.36Å; I161-L176 HydrophobicContact CD1-CD2 4.04Å; I161-L176 HydrophobicContact CD1-CG 4.1Å; P172-L176 PolarHBondContact O-N 2.57Å; P172-L176 VanDerWaalsContact O-N 3.07Å; R173-L176 PolarHBondContact O-N 2.96Å; L176-W179 HydrophobicContact CD1-CE3 4.04Å; L176-W179 WeakPolarHBondContact O-CB 3.2Å; L176-W179 PolarHBondContact O-N 2.76Å; L176-L180 HydrophobicContact CD1-CD1 3.89Å; L176-L180 HydrophobicContact CD1-CG 4.04Å; L176-L180 HydrophobicContact CG-CD1 3.99Å; L176-L180 WeakPolarHBondContact O-CG 3.25Å; L176-L180 PolarHBondContact O-N 3.5Å; L176-Y237 HydrophobicContact CB-CD2 3.94Å; L176-Y237 HydrophobicContact CB-CE2 4.12Å; L176-Y237 HydrophobicContact CB-CG 4.3Å; L176-Y237 HydrophobicContact CD1-CD1 4.23Å; L176-Y237 HydrophobicContact CD1-CD2 4.27Å; L176-Y237 HydrophobicContact CD1-CE1 3.7Å; L176-Y237 HydrophobicContact CD1-CE2 3.76Å; L176-Y237 VanDerWaalsContact CD1-CZ 3.45Å; L176-Y237 HydrophobicContact CG-CE2 4.41Å
177Y81.5Confident87.5Confident19 Ų1929.3 Ų29.38%0.07514%0.136CC..Hα-helixtrans-62.6-42.7175.3-174.9-88.5000112.1E154 L155 C159 I161 R173 A174 F175 W179 L180 Y181 G182 V183E154-Y177 HydrophobicContact CG-CE1 3.93Å; E154-Y177 PolarHBondContact OE1-OH 3.26Å; L155-Y177 HydrophobicContact CD2-CD1 3.81Å; L155-Y177 HydrophobicContact CD2-CE1 4.44Å; L155-Y177 HydrophobicContact CD2-CG 4.44Å; C159-Y177 HydrophobicContact CB-CD1 4.44Å; C159-Y177 HydrophobicContact CB-CD2 3.72Å; C159-Y177 HydrophobicContact CB-CE2 3.96Å; C159-Y177 HydrophobicContact CB-CG 3.98Å; C159-Y177 VanDerWaalsContact SG-CB 3.54Å; C159-Y177 WeakPolarHBondContact SG-CD2 3.3Å; C159-Y177 VanDerWaalsContact SG-CG 3.53Å; I161-Y177 HydrophobicContact CG1-CD2 4.48Å; R173-Y177 PolarHBondContact O-N 2.92Å; A174-Y177 WeakPolarHBondContact O-CB 3.34Å; A174-Y177 PolarHBondContact O-N 3.18Å; F175-Y177 VanDerWaalsContact C-N 3.34Å; F175-Y177 PolarHBondContact O-N 3.35Å; Y177-W179 VanDerWaalsContact C-N 3.25Å; Y177-W179 PolarHBondContact O-N 3.12Å; Y177-L180 PolarHBondContact O-N 3.48Å; Y177-Y181 AromaticContact CD2-CD2 3.36Å; Y177-Y181 HydrophobicContact CD2-CD2 3.36Å; Y177-Y181 AromaticContact CD2-CE2 3.96Å; Y177-Y181 HydrophobicContact CD2-CE2 3.96Å; Y177-Y181 HydrophobicContact CD2-CG 4.3Å; Y177-Y181 AromaticContact CE2-CD2 3.45Å; Y177-Y181 HydrophobicContact CE2-CD2 3.45Å; Y177-Y181 VanDerWaalsContact CE2-CD2 3.45Å; Y177-Y181 HydrophobicContact CE2-CE2 4.12Å; Y177-Y181 HydrophobicContact CE2-CG 4.04Å; Y177-Y181 AromaticContact CG-CD2 3.99Å; Y177-Y181 HydrophobicContact CG-CD2 3.99Å; Y177-Y181 PolarHBondContact O-N 3.44Å; Y177-G182 PolarHBondContact O-N 3.05Å; Y177-V183 HydrophobicContact CD1-CG2 4.21Å
178W91Very high87.8Confident0 Ų026.5 Ų26.50%013%0.126CC..Hα-helixtrans-60.8-35175.8-177.237.1000112.7M134 T138 L150 A174 F175 G182 V183 H232 A234 A295M134-W178 HydrophobicContact CB-CD2 4.11Å; M134-W178 HydrophobicContact CB-CE3 4.18Å; M134-W178 HydrophobicContact CB-CH2 4Å; M134-W178 HydrophobicContact CB-CZ2 3.98Å; M134-W178 HydrophobicContact CB-CZ3 4.11Å; M134-W178 HydrophobicContact CE-CB 3.72Å; M134-W178 HydrophobicContact CE-CD2 4.48Å; M134-W178 HydrophobicContact CE-CE3 4.46Å; M134-W178 HydrophobicContact CE-CG 4.24Å; M134-W178 HydrophobicContact CG-CD2 3.65Å; M134-W178 HydrophobicContact CG-CE3 3.53Å; M134-W178 HydrophobicContact CG-CG 4.17Å; M134-W178 HydrophobicContact CG-CH2 4.21Å; M134-W178 HydrophobicContact CG-CZ2 4.38Å; M134-W178 HydrophobicContact CG-CZ3 3.81Å; M134-W178 HydrophobicContact SD-CB 3.92Å; M134-W178 HydrophobicContact SD-CD2 4Å; M134-W178 HydrophobicContact SD-CE3 4.33Å; M134-W178 HydrophobicContact SD-CG 3.86Å; T138-W178 WeakPolarHBondContact OG1-CZ2 3.24Å; L150-W178 HydrophobicContact CD1-CZ2 4.27Å; A174-W178 PolarHBondContact O-N 2.65Å; F175-W178 AromaticContact CD1-CE3 3.97Å; F175-W178 HydrophobicContact CD1-CE3 3.97Å; F175-W178 HydrophobicContact CD1-CZ3 4.32Å; F175-W178 PolarHBondContact O-N 2.87Å; W178-G182 VanDerWaalsContact O-CA 3.31Å; W178-G182 WeakPolarHBondContact O-CA 3.47Å; W178-G182 PolarHBondContact O-N 2.64Å; W178-V183 HydrophobicContact CB-CG2 4.02Å; W178-V183 HydrophobicContact CG-CG2 4.19Å; W178-H232 PolarHBondContact NE1-O 2.66Å; W178-A234 HydrophobicContact CB-CB 4.46Å; W178-A234 HydrophobicContact CD2-CB 3.53Å; W178-A234 HydrophobicContact CE3-CB 3.4Å; W178-A234 VanDerWaalsContact CE3-CB 3.4Å; W178-A234 HydrophobicContact CG-CB 3.97Å; W178-A234 HydrophobicContact CZ3-CB 3.96Å; W178-A234 PolarHBondContact O-N 3.32Å; W178-A295 HydrophobicContact CH2-CB 3.7Å; W178-A295 HydrophobicContact CZ2-CB 3.84Å
179W83.7Confident88Confident93 Ų9332.4 Ų32.435%0.35215%0.148SC..Hα-helixtrans-71.4-46.7173.4-179.576000112.8F175 L176 Y177 A234 T235 Y237F175-W179 PolarHBondContact O-N 3.31Å; L176-W179 HydrophobicContact CD1-CE3 4.04Å; L176-W179 WeakPolarHBondContact O-CB 3.2Å; L176-W179 PolarHBondContact O-N 2.76Å; Y177-W179 VanDerWaalsContact C-N 3.25Å; Y177-W179 PolarHBondContact O-N 3.12Å; W179-A234 HydrophobicContact CB-CB 4.04Å; W179-T235 PolarHBondContact NE1-O 3.04Å; W179-Y237 HydrophobicContact CB-CD1 3.77Å; W179-Y237 HydrophobicContact CB-CE1 4.46Å; W179-Y237 AromaticContact CD2-CD1 3.98Å; W179-Y237 HydrophobicContact CD2-CD1 3.98Å; W179-Y237 AromaticContact CD2-CE1 3.84Å; W179-Y237 HydrophobicContact CD2-CE1 3.84Å; W179-Y237 HydrophobicContact CE3-CD1 4.19Å; W179-Y237 AromaticContact CE3-CE1 3.71Å; W179-Y237 HydrophobicContact CE3-CE1 3.71Å; W179-Y237 AromaticContact CG-CD1 3.77Å; W179-Y237 HydrophobicContact CG-CD1 3.77Å; W179-Y237 HydrophobicContact CG-CE1 4.15Å; W179-Y237 HydrophobicContact CZ3-CE1 4.29Å
180L70.5Confident88.1Confident76 Ų7635.1 Ų35.140%0.39818%0.175SC..Hα-helixtrans-72.1-45.7-176.2-75.5174.2000113.8I161 L176 Y177I161-L180 HydrophobicContact CD1-CD1 4.34Å; L176-L180 HydrophobicContact CD1-CD1 3.89Å; L176-L180 HydrophobicContact CD1-CG 4.04Å; L176-L180 HydrophobicContact CG-CD1 3.99Å; L176-L180 WeakPolarHBondContact O-CG 3.25Å; L176-L180 PolarHBondContact O-N 3.5Å; Y177-L180 PolarHBondContact O-N 3.48Å
181Y80.8Confident88.4Confident126 Ų12635.2 Ų35.249%0.49418%0.18SC..THydrogen-bonded Turntrans-120.9-14.5-165.8-57.2-69.3000113.4Y177 R231 F233Y177-Y181 AromaticContact CD2-CD2 3.36Å; Y177-Y181 HydrophobicContact CD2-CD2 3.36Å; Y177-Y181 AromaticContact CD2-CE2 3.96Å; Y177-Y181 HydrophobicContact CD2-CE2 3.96Å; Y177-Y181 HydrophobicContact CD2-CG 4.3Å; Y177-Y181 AromaticContact CE2-CD2 3.45Å; Y177-Y181 HydrophobicContact CE2-CD2 3.45Å; Y177-Y181 VanDerWaalsContact CE2-CD2 3.45Å; Y177-Y181 HydrophobicContact CE2-CE2 4.12Å; Y177-Y181 HydrophobicContact CE2-CG 4.04Å; Y177-Y181 AromaticContact CG-CD2 3.99Å; Y177-Y181 HydrophobicContact CG-CD2 3.99Å; Y177-Y181 PolarHBondContact O-N 3.44Å; Y181-R231 WeakPolarHBondContact O-CD 3.13Å; Y181-R231 PolarHBondContact O-NH1 3.13Å; Y181-F233 WeakPolarHBondContact O-CE1 3.4Å
182G89.6Confident88.3Confident0 Ų039.7 Ų39.70%020%0.204CC..  trans67.3158.4-171.200000112.4Y177 W178 R231 H232 F233Y177-G182 PolarHBondContact O-N 3.05Å; W178-G182 VanDerWaalsContact O-CA 3.31Å; W178-G182 WeakPolarHBondContact O-CA 3.47Å; W178-G182 PolarHBondContact O-N 2.64Å; G182-R231 PolarHBondContact O-NH1 2.92Å; G182-H232 CarbonylContact C-O 3.42Å; G182-H232 WeakPolarHBondContact CA-O 3.34Å; G182-F233 VanDerWaalsContact N-CE1 3.32Å
183V95.8Very high88.6Confident0 Ų046.4 Ų46.40%024%0.239CC..BIsolated β-bridgetrans-118.3130.3179.4-179.30000107.9M134 L150 S151 E154 L155 Y177 W178 H232M134-V183 HydrophobicContact SD-CG2 4Å; L150-V183 HydrophobicContact CB-CG1 3.99Å; S151-V183 WeakPolarHBondContact O-CG1 3.35Å; E154-V183 HydrophobicContact CB-CG1 4.44Å; L155-V183 HydrophobicContact CD2-CG2 3.95Å; Y177-V183 HydrophobicContact CD1-CG2 4.21Å; W178-V183 HydrophobicContact CB-CG2 4.02Å; W178-V183 HydrophobicContact CG-CG2 4.19Å; V183-H232 PolarHBondContact N-O 3.17Å; V183-H232 PolarHBondContact O-N 3.26Å
184P96.6Very high89.1Confident0 Ų043.2 Ų43.20%023%0.229CC..  trans-73.7171.2176.234.4-35.7000111.4S151 E154 C195 K196 L227 D230S151-P184 WeakPolarHBondContact CB-O 3.49Å; S151-P184 PolarHBondContact N-O 2.91Å; E154-P184 HydrophobicContact CB-CG 4Å; E154-P184 HydrophobicContact CG-CG 4.17Å; P184-C195 HydrophobicContact CB-CB 4.15Å; P184-K196 HydrophobicContact CG-CB 4.35Å; P184-K196 HydrophobicContact CG-CD 4.05Å; P184-K196 HydrophobicContact CG-CG 4.26Å; P184-L227 HydrophobicContact CB-CD1 3.75Å; P184-L227 HydrophobicContact CG-CD1 3.77Å; P184-D230 WeakPolarHBondContact CA-O 3.34Å
185T97.1Very high89.4Confident6 Ų643.2 Ų43.24%0.03723%0.229CC..BIsolated β-bridgetrans-63.3144.1170.961.70000111V148 F149 C195 K196 Y223 D230V148-T185 HydrophobicContact CB-CG2 4.02Å; V148-T185 HydrophobicContact CG1-CG2 4.39Å; V148-T185 HydrophobicContact CG2-CG2 4.03Å; F149-T185 CarbonylContact O-C 3.55Å; F149-T185 VanDerWaalsContact O-CA 3.22Å; F149-T185 WeakPolarHBondContact O-CA 3.34Å; T185-C195 PolarHBondContact O-N 3.5Å; T185-C195 PolarHBondContact OG1-N 3.38Å; T185-K196 PolarHBondContact O-N 3.14Å; T185-Y223 PolarHBondContact OG1-OH 3.24Å; T185-D230 WeakPolarHBondContact CB-OD2 3.34Å; T185-D230 WeakPolarHBondContact CG2-OD1 3.5Å; T185-D230 PolarHBondContact N-OD2 2.83Å; T185-D230 PolarHBondContact OG1-OD1 3.31Å; T185-D230 PolarHBondContact OG1-OD2 2.89Å
186G96Very high89.7Confident0 Ų043.4 Ų43.40%023%0.23CC..  trans-141.6175173.300000110.8F149 T194 K196F149-G186 WeakPolarHBondContact CB-O 3.28Å; F149-G186 PolarHBondContact O-N 2.85Å; F149-G186 VanDerWaalsContact O-O 3.11Å; G186-T194 VanDerWaalsContact C-OG1 3.25Å; G186-T194 WeakPolarHBondContact O-CG2 3.47Å; G186-K196 WeakPolarHBondContact CA-O 3.36Å
187G91.9Very high90.3Very high8 Ų842.7 Ų42.78%0.08223%0.227CC..  trans-165.4177.1-174.100000110.9T194 P197 Y198G187-T194 PolarHBondContact N-OG1 2.81Å; G187-P197 CarbonylContact O-C 3.57Å; G187-P197 WeakPolarHBondContact O-CA 3.46Å; G187-Y198 PolarHBondContact O-N 3.47Å
188S92.5Very high91Very high70 Ų7042.1 Ų42.149%0.4923%0.225SC..SBendtrans-60.2158.8179.6-54.30000112.3G190 S191S188-G190 PolarHBondContact O-N 3.06Å; S188-S191 VanDerWaalsContact O-CB 3.26Å; S188-S191 WeakPolarHBondContact O-CB 3.21Å; S188-S191 PolarHBondContact O-N 3.33Å
189Y91.8Very high91.1Very high130 Ų13044.8 Ų44.851%0.5124%0.244SC..THydrogen-bonded Turntrans-47.1129.6173.5177.5-92.5000112.6Y198 S199 A201Y189-Y198 WeakPolarHBondContact CA-O 3.25Å; Y189-S199 WeakPolarHBondContact CD2-O 3.23Å; Y189-S199 VanDerWaalsContact CE2-O 3.32Å; Y189-S199 WeakPolarHBondContact CE2-O 3.44Å; Y189-A201 HydrophobicContact CD1-CB 4.11Å; Y189-A201 HydrophobicContact CD2-CB 4.05Å; Y189-A201 HydrophobicContact CE1-CB 3.88Å; Y189-A201 HydrophobicContact CE2-CB 3.82Å; Y189-A201 HydrophobicContact CG-CB 4.19Å
190G87.4Confident91.5Very high59 Ų5941 Ų4161%0.60823%0.23SC*.THydrogen-bonded Turntrans83.4-1.9-179.700000115.8S188S188-G190 PolarHBondContact O-N 3.06Å
191S89.9Confident92.4Very high28 Ų2839.3 Ų39.320%0.19623%0.227CC..  trans-69.7136.9172.8178.70000111.2S188 D193 P197S188-S191 VanDerWaalsContact O-CB 3.26Å; S188-S191 WeakPolarHBondContact O-CB 3.21Å; S188-S191 PolarHBondContact O-N 3.33Å; S191-D193 PolarHBondContact OG-N 3.01Å; S191-P197 WeakPolarHBondContact O-CB 3.41Å; S191-P197 VanDerWaalsContact O-CG 3.24Å; S191-P197 WeakPolarHBondContact O-CG 3.27Å
192N88.1Confident92.7Very high99 Ų9937.2 Ų37.253%0.52923%0.229SC..  trans-110.43.4171.6-68.3-31.2000112.6T194N192-T194 VanDerWaalsContact C-N 3.31Å
193D89.5Confident92.2Very high142 Ų14239 Ų3976%0.75924%0.241SC*.SBendtrans-90.43.3-174-54.3-44.7000112.7S191 Y223S191-D193 PolarHBondContact OG-N 3.01Å; D193-Y223 WeakPolarHBondContact O-CE2 3.36Å
194T94.4Very high91Very high20 Ų2046.3 Ų46.312%0.12327%0.273CS..SBendtrans-136.2155.2-17762.40000109.9G186 G187 N192 V220 Y223G186-T194 VanDerWaalsContact C-OG1 3.25Å; G186-T194 WeakPolarHBondContact O-CG2 3.47Å; G187-T194 PolarHBondContact N-OG1 2.81Å; N192-T194 VanDerWaalsContact C-N 3.31Å; T194-V220 VanDerWaalsContact O-CG2 3.29Å; T194-V220 WeakPolarHBondContact O-CG2 3.39Å; T194-Y223 VanDerWaalsContact C-CD2 3.43Å; T194-Y223 VanDerWaalsContact C-CE2 3.5Å; T194-Y223 VanDerWaalsContact CA-CE2 3.45Å
195C96.4Very high89.6Confident0 Ų053.3 Ų53.30%031%0.309CS..SBendtrans-65.2-44.3-173.3173.50000112.7P184 T185 C219 V220 Y223 L227 D230P184-C195 HydrophobicContact CB-CB 4.15Å; T185-C195 PolarHBondContact O-N 3.5Å; T185-C195 PolarHBondContact OG1-N 3.38Å; C195-C219 HydrophobicContact CB-CB 3.83Å; C195-C219 WeakPolarHBondContact CB-SG 3.39Å; C195-C219 CarbonylContact O-C 3.47Å; C195-C219 VanDerWaalsContact O-CA 3.23Å; C195-C219 WeakPolarHBondContact O-CA 2.72Å; C195-C219 WeakPolarHBondContact O-CB 3.3Å; C195-C219 VanDerWaalsContact SG-CA 3.53Å; C195-C219 WeakPolarHBondContact SG-CB 3.35Å; C195-C219 CovalentContact SG-SG 2.03Å; C195-C219 PolarHBondContact SG-SG 2.87Å; C195-V220 PolarHBondContact O-N 3.1Å; C195-Y223 HydrophobicContact CB-CD1 3.78Å; C195-Y223 HydrophobicContact CB-CE1 3.65Å; C195-Y223 HydrophobicContact CB-CG 4.39Å; C195-L227 VanDerWaalsContact SG-CD1 3.53Å; C195-D230 HydrophobicContact CB-CB 4.36Å; C195-D230 WeakPolarHBondContact CB-OD2 3.14Å
196K96.2Very high88.3Confident5 Ų554.2 Ų54.22%0.02232%0.315CS..SBendtrans-133.977.6-176.6-73.7-163.6169.3-163.30111.9S151 E154 C158 P184 T185 G186 T216 L227S151-K196 WeakPolarHBondContact CB-O 3.17Å; S151-K196 WeakPolarHBondContact OG-CB 3.34Å; S151-K196 PolarHBondContact OG-O 3.3Å; E154-K196 HydrophobicContact CB-CD 4.19Å; E154-K196 WeakPolarHBondContact OE2-CD 3.48Å; E154-K196 WeakPolarHBondContact OE2-CE 3.37Å; E154-K196 IonicContact OE2-NZ 2.88Å; E154-K196 PolarHBondContact OE2-NZ 3.03Å; C158-K196 PolarHBondContact SG-NZ 3.5Å; P184-K196 HydrophobicContact CG-CB 4.35Å; P184-K196 HydrophobicContact CG-CD 4.05Å; P184-K196 HydrophobicContact CG-CG 4.26Å; T185-K196 PolarHBondContact O-N 3.14Å; G186-K196 WeakPolarHBondContact CA-O 3.36Å; K196-T216 WeakPolarHBondContact CE-OG1 3.06Å; K196-T216 PolarHBondContact NZ-O 3.07Å; K196-T216 PolarHBondContact NZ-OG1 3.09Å; K196-L227 HydrophobicContact CD-CD1 4.44Å
197P95.6Very high86.9Confident15 Ų1564.7 Ų64.710%0.09736%0.361CS..  trans-63.5155.7172.532.5-40.4000111.7G187 S191 S199 V220G187-P197 CarbonylContact O-C 3.57Å; G187-P197 WeakPolarHBondContact O-CA 3.46Å; S191-P197 WeakPolarHBondContact O-CB 3.41Å; S191-P197 VanDerWaalsContact O-CG 3.24Å; S191-P197 WeakPolarHBondContact O-CG 3.27Å; P197-S199 PolarHBondContact O-N 3.01Å; P197-V220 HydrophobicContact CG-CG1 3.73Å; P197-V220 HydrophobicContact CG-CG2 4.35Å
198Y95.3Very high85.9Confident7 Ų766.1 Ų66.13%0.02738%0.375CS..  trans-63.2125.4177.7-164.3-130.8000110.9D118 Q119 S124 E152 I156 G187 Y189 I200D118-Y198 WeakPolarHBondContact O-CE1 3.43Å; Q119-Y198 PolarHBondContact O-OH 3.15Å; S124-Y198 PolarHBondContact OG-OH 2.65Å; E152-Y198 HydrophobicContact CG-CD2 3.53Å; E152-Y198 HydrophobicContact CG-CE2 4Å; E152-Y198 HydrophobicContact CG-CG 4.17Å; I156-Y198 HydrophobicContact CD1-CD2 4.34Å; I156-Y198 HydrophobicContact CD1-CE2 3.52Å; G187-Y198 PolarHBondContact O-N 3.47Å; Y189-Y198 WeakPolarHBondContact CA-O 3.25Å; Y198-I200 HydrophobicContact CD1-CB 4.27Å; Y198-I200 WeakPolarHBondContact CD1-O 3.07Å; Y198-I200 HydrophobicContact CE1-CB 3.76Å; Y198-I200 HydrophobicContact CE1-CG1 4.47Å; Y198-I200 HydrophobicContact CE2-CD1 4.36Å; Y198-I200 HydrophobicContact CE2-CG1 4.43Å
199S93.4Very high85.2Confident56 Ų5666.4 Ų66.439%0.39237%0.371SS..  trans-85.5-11.7-173.662.50000114.3E153 Y189 P197 P213E153-S199 VanDerWaalsContact CD-OG 3.25Å; E153-S199 PolarHBondContact OE1-OG 2.81Å; E153-S199 VanDerWaalsContact OE2-CB 3.3Å; E153-S199 WeakPolarHBondContact OE2-CB 3.46Å; E153-S199 PolarHBondContact OE2-N 3.19Å; E153-S199 PolarHBondContact OE2-OG 3.46Å; Y189-S199 WeakPolarHBondContact CD2-O 3.23Å; Y189-S199 VanDerWaalsContact CE2-O 3.32Å; Y189-S199 WeakPolarHBondContact CE2-O 3.44Å; P197-S199 PolarHBondContact O-N 3.01Å; S199-P213 WeakPolarHBondContact OG-CB 3.33Å; S199-P213 WeakPolarHBondContact OG-CG 3.19Å
200I92.8Very high84.8Confident14 Ų1462 Ų627%0.07236%0.359CS..SBendtrans-96.1117-174.8-50.4-179.8000109.8C122 Y198 S210 P213C122-I200 HydrophobicContact CB-CD1 3.51Å; Y198-I200 HydrophobicContact CD1-CB 4.27Å; Y198-I200 WeakPolarHBondContact CD1-O 3.07Å; Y198-I200 HydrophobicContact CE1-CB 3.76Å; Y198-I200 HydrophobicContact CE1-CG1 4.47Å; Y198-I200 HydrophobicContact CE2-CD1 4.36Å; Y198-I200 HydrophobicContact CE2-CG1 4.43Å; I200-S210 WeakPolarHBondContact CG2-OG 3.26Å; I200-P213 HydrophobicContact CD1-CG 4.15Å; I200-P213 HydrophobicContact CG1-CG 4.14Å
201A88.8Confident84.8Confident41 Ų4166.3 Ų66.334%0.33937%0.368SS..PPolyproline II helixtrans-66138.5-176.200000112.2S120 Y189 C203S120-A201 WeakPolarHBondContact CB-O 3.38Å; S120-A201 PolarHBondContact OG-O 3.13Å; Y189-A201 HydrophobicContact CD1-CB 4.11Å; Y189-A201 HydrophobicContact CD2-CB 4.05Å; Y189-A201 HydrophobicContact CE1-CB 3.88Å; Y189-A201 HydrophobicContact CE2-CB 3.82Å; Y189-A201 HydrophobicContact CG-CB 4.19Å; A201-C203 PolarHBondContact O-N 3.25Å
202P86.8Confident84.9Confident81 Ų8167.5 Ų67.553%0.52638%0.375SS..PPolyproline II helixtrans-55.1136.3169.8-26.635.1000111.8D118D118-P202 WeakPolarHBondContact OD2-CB 3.39Å
203C80.6Confident85.1Confident37 Ų3763.8 Ų63.825%0.2536%0.356CS..  trans-144.7136.7178.654.80000112.1S120 A201 C206S120-C203 PolarHBondContact OG-SG 2.89Å; A201-C203 PolarHBondContact O-N 3.25Å; C203-C206 HydrophobicContact CB-CB 4.04Å; C203-C206 WeakPolarHBondContact CB-SG 3.39Å; C203-C206 PolarHBondContact O-SG 2.97Å; C203-C206 WeakPolarHBondContact SG-CB 3.5Å; C203-C206 CovalentContact SG-SG 2.02Å; C203-C206 PolarHBondContact SG-SG 2.91Å
204K70.3Confident85.2Confident155 Ų15565.8 Ų65.867%0.67436%0.358SS*.SBendtrans-81.7-48.9172.9-66.1-171.8178.8-171.20111.4
205I66.6Low85.1Confident147 Ų14767.7 Ų67.775%0.75437%0.371SS*.SBendtrans-119.7107.2172.6-56.8172.2000106.8
206C69.9Low84.8Confident25 Ų2571.3 Ų71.317%0.16939%0.393CS..  trans-101.6137.1-175.9-39.80000108.7N121 C203 G208N121-C206 HydrophobicContact CB-CB 3.64Å; N121-C206 VanDerWaalsContact CB-SG 3.58Å; N121-C206 VanDerWaalsContact CG-CB 3.42Å; N121-C206 WeakPolarHBondContact ND2-CB 3.21Å; C203-C206 HydrophobicContact CB-CB 4.04Å; C203-C206 WeakPolarHBondContact CB-SG 3.39Å; C203-C206 PolarHBondContact O-SG 2.97Å; C203-C206 WeakPolarHBondContact SG-CB 3.5Å; C203-C206 CovalentContact SG-SG 2.02Å; C203-C206 PolarHBondContact SG-SG 2.91Å; C206-G208 PolarHBondContact O-N 2.99Å; C206-G208 VanDerWaalsContact O-N 3.08Å
207K67.3Low84.4Confident220 Ų22079.9 Ų79.996%0.95743%0.431SS*.SBendtrans-81.882.5175.1-70.4-172.9-179.6-178.40109.8
208G71Confident84.2Confident37 Ų3786.3 Ų86.338%0.38146%0.459SS..SBendtrans74.3173.3179.500000114.1N121 C206N121-G208 PolarHBondContact ND2-O 2.83Å; C206-G208 PolarHBondContact O-N 2.99Å; C206-G208 VanDerWaalsContact O-N 3.08Å
209N77Confident84.1Confident76 Ų7687 Ų8741%0.40647%0.465SS..PPolyproline II helixtrans-65.3149.2-176.3-60.1-13.3000111.8N64N64-N209 WeakPolarHBondContact CB-OD1 3.48Å; N64-N209 PolarHBondContact ND2-ND2 2.71Å; N64-N209 PolarHBondContact ND2-OD1 2.62Å; N64-N209 VanDerWaalsContact ND2-OD1 3.09Å
210S84.3Confident84.1Confident37 Ų3786.6 Ų86.626%0.25946%0.46SS..PPolyproline II helixtrans-81.1139.4171.1-60.90000111.2N121 C166 I200N121-S210 PolarHBondContact O-N 2.62Å; C166-S210 WeakPolarHBondContact CB-O 3.17Å; I200-S210 WeakPolarHBondContact CG2-OG 3.26Å
211D87.3Confident83.7Confident150 Ų15092.3 Ų92.380%0.80249%0.491SS*.PPolyproline II helixtrans-68.9150171-66.9-36.4000111.1P213D211-P213 VanDerWaalsContact O-CD 3.32Å; D211-P213 WeakPolarHBondContact O-CD 3.46Å
212T92.1Very high83.3Confident54 Ų5497.9 Ų97.933%0.33152%0.515SS..PPolyproline II helixtrans-59.6122172-64.50000110.7I156 M164 C166I156-T212 HydrophobicContact CG2-CG2 4.21Å; M164-T212 PolarHBondContact O-OG1 3.19Å; C166-T212 PolarHBondContact N-OG1 3.48Å
213P92Very high83.6Confident21 Ų2196.1 Ų96.114%0.13650%0.498CS..PPolyproline II helixtrans-59.1151.3176-25.535000113.2E153 S157 S199 I200 D211E153-P213 WeakPolarHBondContact OE1-CB 3.45Å; S157-P213 VanDerWaalsContact CB-O 3.23Å; S157-P213 WeakPolarHBondContact CB-O 3.42Å; S199-P213 WeakPolarHBondContact OG-CB 3.33Å; S199-P213 WeakPolarHBondContact OG-CG 3.19Å; I200-P213 HydrophobicContact CD1-CG 4.15Å; I200-P213 HydrophobicContact CG1-CG 4.14Å; D211-P213 VanDerWaalsContact O-CD 3.32Å; D211-P213 WeakPolarHBondContact O-CD 3.46Å
214K90.8Very high83.8Confident184 Ų184100.4 Ų100.480%0.853%0.526SS*.PPolyproline II helixtrans-78.7133.8179.7-66.7-178.2-178175.50111.2T216K214-T216 PolarHBondContact O-N 3.11Å
215C92.9Very high84.5Confident60 Ų6094.5 Ų94.541%0.40551%0.506SS..PPolyproline II helixtrans-59.1120.8172.7-177.10000112.2S157 C158S157-C215 VanDerWaalsContact O-CB 3.27Å; S157-C215 WeakPolarHBondContact O-CB 3.36Å; C158-C215 VanDerWaalsContact CA-SG 3.55Å; C158-C215 HydrophobicContact CB-CB 3.96Å; C158-C215 WeakPolarHBondContact CB-SG 3.38Å; C158-C215 WeakPolarHBondContact SG-CA 3.3Å; C158-C215 WeakPolarHBondContact SG-CB 3.16Å; C158-C215 CovalentContact SG-SG 2.04Å; C158-C215 PolarHBondContact SG-SG 3.32Å
216T89.8Confident85.5Confident75 Ų7592.3 Ų92.346%0.4650%0.496SS..PPolyproline II helixtrans-102.1151.1171.660.20000111.2K196 K214 E218K196-T216 WeakPolarHBondContact CE-OG1 3.06Å; K196-T216 PolarHBondContact NZ-O 3.07Å; K196-T216 PolarHBondContact NZ-OG1 3.09Å; K214-T216 PolarHBondContact O-N 3.11Å; T216-E218 PolarHBondContact OG1-O 2.89Å
217K88.2Confident86.4Confident185 Ų18592 Ų9280%0.80449%0.492SS*.SBendtrans-101.78.1178.6-68.4-173.7178.7179.30113.8L227K217-L227 VanDerWaalsContact C-CD2 3.46Å; K217-L227 VanDerWaalsContact O-CD2 3.23Å; K217-L227 WeakPolarHBondContact O-CD2 3.47Å
218E90.4Very high87.2Confident150 Ų15090.6 Ų90.670%0.70149%0.486SS*.SBendtrans-133.1154.4-174.8-66.9174-175.700108.8T216T216-E218 PolarHBondContact OG1-O 2.89Å
219C94.1Very high87.9Confident21 Ų2195.5 Ų95.514%0.14250%0.497CS..PPolyproline II helixtrans-72.3165.5170.3-59.80000110.1C195 Y223 A225C195-C219 HydrophobicContact CB-CB 3.83Å; C195-C219 WeakPolarHBondContact CB-SG 3.39Å; C195-C219 CarbonylContact O-C 3.47Å; C195-C219 VanDerWaalsContact O-CA 3.23Å; C195-C219 WeakPolarHBondContact O-CA 2.72Å; C195-C219 WeakPolarHBondContact O-CB 3.3Å; C195-C219 VanDerWaalsContact SG-CA 3.53Å; C195-C219 WeakPolarHBondContact SG-CB 3.35Å; C195-C219 CovalentContact SG-SG 2.03Å; C195-C219 PolarHBondContact SG-SG 2.87Å; C219-Y223 HydrophobicContact CB-CD1 3.89Å; C219-Y223 HydrophobicContact CB-CG 4.23Å; C219-A225 PolarHBondContact SG-O 3.36Å
220V92.4Very high88.7Confident48 Ų4892.5 Ų92.529%0.29148%0.481SS..PPolyproline II helixtrans-57.1149.1170.1-67.90000111.2T194 C195 P197 N222 Y223T194-V220 VanDerWaalsContact O-CG2 3.29Å; T194-V220 WeakPolarHBondContact O-CG2 3.39Å; C195-V220 PolarHBondContact O-N 3.1Å; P197-V220 HydrophobicContact CG-CG1 3.73Å; P197-V220 HydrophobicContact CG-CG2 4.35Å; V220-N222 PolarHBondContact O-N 2.95Å; V220-Y223 WeakPolarHBondContact O-CB 3.34Å; V220-Y223 PolarHBondContact O-N 2.78Å
221N84.4Confident89.1Confident134 Ų13492.6 Ų92.672%0.71748%0.476SS*.THydrogen-bonded Turntrans-56138.2-178.4-67.1-26.1000110.6
222N81.6Confident89.3Confident159 Ų15986.7 Ų86.785%0.8544%0.443SS*.THydrogen-bonded Turntrans77.80.9-176.8-47.5-41000116.7V220V220-N222 PolarHBondContact O-N 2.95Å
223Y92Very high89.1Confident44 Ų4487.5 Ų87.517%0.17344%0.442CS..  trans-71130.7170.7-168.2-106.5000110.8T185 D193 T194 C195 C219 V220 A225 D230T185-Y223 PolarHBondContact OG1-OH 3.24Å; D193-Y223 WeakPolarHBondContact O-CE2 3.36Å; T194-Y223 VanDerWaalsContact C-CD2 3.43Å; T194-Y223 VanDerWaalsContact C-CE2 3.5Å; T194-Y223 VanDerWaalsContact CA-CE2 3.45Å; C195-Y223 HydrophobicContact CB-CD1 3.78Å; C195-Y223 HydrophobicContact CB-CE1 3.65Å; C195-Y223 HydrophobicContact CB-CG 4.39Å; C219-Y223 HydrophobicContact CB-CD1 3.89Å; C219-Y223 HydrophobicContact CB-CG 4.23Å; V220-Y223 WeakPolarHBondContact O-CB 3.34Å; V220-Y223 PolarHBondContact O-N 2.78Å; Y223-A225 HydrophobicContact CD1-CB 4.35Å; Y223-A225 WeakPolarHBondContact CD1-O 3.12Å; Y223-A225 HydrophobicContact CE1-CB 3.87Å; Y223-A225 PolarHBondContact O-N 2.95Å; Y223-D230 HydrophobicContact CE1-CB 4.18Å; Y223-D230 PolarHBondContact OH-OD1 2.94Å
224P86Confident88.8Confident127 Ų12786.8 Ų86.883%0.82544%0.438SS*.SBendtrans-73.2-20.5-167.126.7-35.6000115.1
225A85.5Confident87.9Confident31 Ų3179.7 Ų79.726%0.25641%0.41SS..SBendtrans-109.8145.2-17600000112.4C219 Y223C219-A225 PolarHBondContact SG-O 3.36Å; Y223-A225 HydrophobicContact CD1-CB 4.35Å; Y223-A225 WeakPolarHBondContact CD1-O 3.12Å; Y223-A225 HydrophobicContact CE1-CB 3.87Å; Y223-A225 PolarHBondContact O-N 2.95Å
226D86.8Confident87Confident101 Ų10177 Ų7754%0.5439%0.391SS..  trans-66.4146170.8-57.4-57.9000110.9K228 K229 D230D226-K228 PolarHBondContact O-N 3.12Å; D226-K229 PolarHBondContact O-N 3.08Å; D226-K229 IonicContact OD2-NZ 3.44Å; D226-K229 PolarHBondContact OD2-NZ 3.49Å; D226-D230 PolarHBondContact O-N 2.82Å
227L88.8Confident86.6Confident19 Ų1975.6 Ų75.610%0.09938%0.378CS..THydrogen-bonded Turntrans-48.6-32.8177.3178.264.3000113.7P184 C195 K196 K217 R231P184-L227 HydrophobicContact CB-CD1 3.75Å; P184-L227 HydrophobicContact CG-CD1 3.77Å; C195-L227 VanDerWaalsContact SG-CD1 3.53Å; K196-L227 HydrophobicContact CD-CD1 4.44Å; K217-L227 VanDerWaalsContact C-CD2 3.46Å; K217-L227 VanDerWaalsContact O-CD2 3.23Å; K217-L227 WeakPolarHBondContact O-CD2 3.47Å; L227-R231 WeakPolarHBondContact O-CG 3.32Å
228K83.9Confident86Confident190 Ų19066.8 Ų66.883%0.82634%0.34SS*.THydrogen-bonded Turntrans-70.4-34.8177.8-70.5-178.5-178.7174.90113.2D226D226-K228 PolarHBondContact O-N 3.12Å
229K86.3Confident85.5Confident139 Ų13959.9 Ų59.960%0.60431%0.307SS*.THydrogen-bonded Turntrans-80.6-29.2-177.4-68.8176.4-179.5159.40111.9D226 R231 K298D226-K229 PolarHBondContact O-N 3.08Å; D226-K229 IonicContact OD2-NZ 3.44Å; D226-K229 PolarHBondContact OD2-NZ 3.49Å; K229-R231 VanDerWaalsContact C-N 3.32Å; K229-K298 PolarHBondContact O-NZ 3.43Å
230D93.3Very high84.7Confident14 Ų1458.9 Ų58.98%0.07530%0.301CS..SBendtrans-82.6-2.4-179-165.352.7000114.4P184 T185 C195 Y223 D226 H232P184-D230 WeakPolarHBondContact CA-O 3.34Å; T185-D230 WeakPolarHBondContact CB-OD2 3.34Å; T185-D230 WeakPolarHBondContact CG2-OD1 3.5Å; T185-D230 PolarHBondContact N-OD2 2.83Å; T185-D230 PolarHBondContact OG1-OD1 3.31Å; T185-D230 PolarHBondContact OG1-OD2 2.89Å; C195-D230 HydrophobicContact CB-CB 4.36Å; C195-D230 WeakPolarHBondContact CB-OD2 3.14Å; Y223-D230 HydrophobicContact CE1-CB 4.18Å; Y223-D230 PolarHBondContact OH-OD1 2.94Å; D226-D230 PolarHBondContact O-N 2.82Å; D230-H232 PolarHBondContact O-CD2 3.49Å; D230-H232 PolarHBondContact O-N 3.11Å; D230-H232 PolarHBondContact O-NE2 3.26Å
231R91.9Very high83.4Confident39 Ų3959.4 Ų59.415%0.14730%0.297CS..  trans-73.9129.3179.3-79.5167-174.7-75.8-5.2112.2E154 Y181 G182 L227 K229 F233E154-R231 IonicContact OE1-CZ 2.64Å; E154-R231 VanDerWaalsContact OE1-CZ 3.32Å; E154-R231 IonicContact OE1-NH1 3.54Å; E154-R231 PolarHBondContact OE1-NH1 3.21Å; E154-R231 IonicContact OE1-NH2 2.66Å; E154-R231 PolarHBondContact OE1-NH2 3.4Å; E154-R231 IonicContact OE2-NH2 3.74Å; Y181-R231 WeakPolarHBondContact O-CD 3.13Å; Y181-R231 PolarHBondContact O-NH1 3.13Å; G182-R231 PolarHBondContact O-NH1 2.92Å; L227-R231 WeakPolarHBondContact O-CG 3.32Å; K229-R231 VanDerWaalsContact C-N 3.32Å; R231-F233 HydrophobicContact CB-CD2 4.47Å; R231-F233 HydrophobicContact CB-CE2 3.67Å; R231-F233 HydrophobicContact CB-CZ 4.03Å
232H92.5Very high82Confident26 Ų2658.4 Ų58.412%0.1229%0.291CS..BIsolated β-bridgetrans-104.1137.8170.9-61.7-100.3000109.2L150 W178 G182 V183 D230L150-H232 HydrophobicContact CD1-CB 4.23Å; L150-H232 HydrophobicContact CD2-CB 3.74Å; W178-H232 PolarHBondContact NE1-O 2.66Å; G182-H232 CarbonylContact C-O 3.42Å; G182-H232 WeakPolarHBondContact CA-O 3.34Å; V183-H232 PolarHBondContact N-O 3.17Å; V183-H232 PolarHBondContact O-N 3.26Å; D230-H232 PolarHBondContact O-CD2 3.49Å; D230-H232 PolarHBondContact O-N 3.11Å; D230-H232 PolarHBondContact O-NE2 3.26Å
233F88.5Confident81.2Confident71 Ų7152 Ų5231%0.31126%0.263SS..  trans-117.2153.4-170.9-69.6-98.6000111.5Y181 G182 R231 K296Y181-F233 WeakPolarHBondContact O-CE1 3.4Å; G182-F233 VanDerWaalsContact N-CE1 3.32Å; R231-F233 HydrophobicContact CB-CD2 4.47Å; R231-F233 HydrophobicContact CB-CE2 3.67Å; R231-F233 HydrophobicContact CB-CZ 4.03Å; F233-K296 HydrophobicContact CB-CB 4.33Å; F233-K296 HydrophobicContact CB-CD 4.08Å; F233-K296 WeakPolarHBondContact O-CB 3.29Å; F233-K296 PolarHBondContact O-N 3.3Å
234A83.8Confident80.3Confident5 Ų556.7 Ų56.74%0.04129%0.286CS..EExtended strand (participates in β ladder)trans-80.8155163.800000110.9W178 W179 T236 R294W178-A234 HydrophobicContact CB-CB 4.46Å; W178-A234 HydrophobicContact CD2-CB 3.53Å; W178-A234 HydrophobicContact CE3-CB 3.4Å; W178-A234 VanDerWaalsContact CE3-CB 3.4Å; W178-A234 HydrophobicContact CG-CB 3.97Å; W178-A234 HydrophobicContact CZ3-CB 3.96Å; W178-A234 PolarHBondContact O-N 3.32Å; W179-A234 HydrophobicContact CB-CB 4.04Å; A234-T236 WeakPolarHBondContact CB-O 3.28Å; A234-R294 CarbonylContact C-O 3.59Å; A234-R294 WeakPolarHBondContact CA-O 3.09Å; A234-R294 WeakPolarHBondContact CB-O 3.48Å
235T73.9Confident79.9Confident36 Ų3658.8 Ų58.822%0.22128%0.283CS..EExtended strand (participates in β ladder)trans-84.5-26.815954.30000111.5W179 R294 K296W179-T235 PolarHBondContact NE1-O 3.04Å; T235-R294 PolarHBondContact N-O 2.7Å; T235-R294 WeakPolarHBondContact OG1-CB 3.22Å; T235-R294 PolarHBondContact OG1-O 3.46Å; T235-K296 HydrophobicContact CG2-CB 3.74Å; T235-K296 HydrophobicContact CG2-CG 3.95Å
236T73.8Confident79.5Confident2 Ų258.3 Ų58.31%0.01228%0.277CS..EExtended strand (participates in β ladder)trans-161.6168.2-176.9-162.40000113.4Y87 A234 Y238 G293 R294 I538Y87-T236 HydrophobicContact CD2-CG2 4.44Å; Y87-T236 HydrophobicContact CE1-CG2 4.4Å; Y87-T236 WeakPolarHBondContact CE1-OG1 3.27Å; Y87-T236 HydrophobicContact CE2-CG2 4.3Å; Y87-T236 PolarHBondContact OH-OG1 2.77Å; A234-T236 WeakPolarHBondContact CB-O 3.28Å; T236-Y238 HydrophobicContact CG2-CD1 4Å; T236-Y238 HydrophobicContact CG2-CE1 3.82Å; T236-G293 CarbonylContact O-C 3.45Å; T236-G293 WeakPolarHBondContact O-CA 3.19Å; T236-R294 HydrophobicContact CG2-CB 3.89Å; T236-R294 HydrophobicContact CG2-CG 3.79Å; T236-R294 PolarHBondContact O-N 3.25Å; T236-R294 VanDerWaalsContact O-N 3.11Å; T236-I538 VanDerWaalsContact CB-CG2 3.48Å; T236-I538 HydrophobicContact CG2-CG2 3.79Å
237Y80Confident79.4Confident46 Ų4654.5 Ų54.518%0.1826%0.256CS..EExtended strand (participates in β ladder)trans-149.1137.6-176.965.7-81.9000111.3F81 P82 Y87 L176 W179 A292F81-Y237 AromaticContact CD1-CD2 3.83Å; F81-Y237 HydrophobicContact CD1-CD2 3.83Å; F81-Y237 AromaticContact CD1-CE2 3.83Å; F81-Y237 HydrophobicContact CD1-CE2 3.83Å; F81-Y237 HydrophobicContact CE1-CD2 4.24Å; F81-Y237 HydrophobicContact CE1-CE2 4.22Å; P82-Y237 VanDerWaalsContact CG-O 3.27Å; P82-Y237 WeakPolarHBondContact CG-O 3.34Å; Y87-Y237 PolarHBondContact OH-O 3.3Å; L176-Y237 HydrophobicContact CB-CD2 3.94Å; L176-Y237 HydrophobicContact CB-CE2 4.12Å; L176-Y237 HydrophobicContact CB-CG 4.3Å; L176-Y237 HydrophobicContact CD1-CD1 4.23Å; L176-Y237 HydrophobicContact CD1-CD2 4.27Å; L176-Y237 HydrophobicContact CD1-CE1 3.7Å; L176-Y237 HydrophobicContact CD1-CE2 3.76Å; L176-Y237 VanDerWaalsContact CD1-CZ 3.45Å; L176-Y237 HydrophobicContact CG-CE2 4.41Å; W179-Y237 HydrophobicContact CB-CD1 3.77Å; W179-Y237 HydrophobicContact CB-CE1 4.46Å; W179-Y237 AromaticContact CD2-CD1 3.98Å; W179-Y237 HydrophobicContact CD2-CD1 3.98Å; W179-Y237 AromaticContact CD2-CE1 3.84Å; W179-Y237 HydrophobicContact CD2-CE1 3.84Å; W179-Y237 HydrophobicContact CE3-CD1 4.19Å; W179-Y237 AromaticContact CE3-CE1 3.71Å; W179-Y237 HydrophobicContact CE3-CE1 3.71Å; W179-Y237 AromaticContact CG-CD1 3.77Å; W179-Y237 HydrophobicContact CG-CD1 3.77Å; W179-Y237 HydrophobicContact CG-CE1 4.15Å; W179-Y237 HydrophobicContact CZ3-CE1 4.29Å; Y237-A292 CarbonylContact C-O 3.56Å
238Y76.7Confident79.2Confident1 Ų157 Ų570%0.00427%0.268CS..EExtended strand (participates in β ladder)trans-156.6163.9-172.545-90.7000114.6P82 P84 Y87 R137 T236 F240 D250 S291 A292 R294P82-Y238 VanDerWaalsContact O-CA 3.25Å; P82-Y238 WeakPolarHBondContact O-CA 3.33Å; P82-Y238 WeakPolarHBondContact O-CB 3.41Å; P84-Y238 HydrophobicContact CB-CD2 3.74Å; P84-Y238 HydrophobicContact CB-CE2 3.67Å; P84-Y238 HydrophobicContact CB-CG 4.36Å; P84-Y238 HydrophobicContact CG-CD2 3.48Å; P84-Y238 VanDerWaalsContact CG-CD2 3.48Å; P84-Y238 HydrophobicContact CG-CE2 3.7Å; P84-Y238 HydrophobicContact CG-CG 4.35Å; Y87-Y238 AromaticContact CD2-CD1 3.91Å; Y87-Y238 HydrophobicContact CD2-CD1 3.91Å; Y87-Y238 HydrophobicContact CD2-CE1 4.28Å; Y87-Y238 HydrophobicContact CD2-CG 4.46Å; Y87-Y238 AromaticContact CE2-CD1 3.21Å; Y87-Y238 HydrophobicContact CE2-CD1 3.21Å; Y87-Y238 HydrophobicContact CE2-CE1 4Å; Y87-Y238 AromaticContact CE2-CG 3.65Å; Y87-Y238 HydrophobicContact CE2-CG 3.65Å; Y87-Y238 AromaticContact CZ-CD1 3.95Å; R137-Y238 PolarHBondContact NH1-OH 3.14Å; T236-Y238 HydrophobicContact CG2-CD1 4Å; T236-Y238 HydrophobicContact CG2-CE1 3.82Å; Y238-F240 HydrophobicContact CD2-CE2 4.07Å; Y238-F240 HydrophobicContact CD2-CZ 4.19Å; Y238-F240 AromaticContact CE2-CE2 3.96Å; Y238-F240 HydrophobicContact CE2-CE2 3.96Å; Y238-F240 AromaticContact CE2-CZ 3.75Å; Y238-F240 HydrophobicContact CE2-CZ 3.75Å; Y238-D250 WeakPolarHBondContact CE2-OD2 3.31Å; Y238-D250 PolarHBondContact OH-OD1 2.81Å; Y238-D250 PolarHBondContact OH-OD2 2.85Å; Y238-S291 VanDerWaalsContact O-CA 3.29Å; Y238-S291 WeakPolarHBondContact O-CA 3.39Å; Y238-S291 VanDerWaalsContact O-CB 3.3Å; Y238-S291 WeakPolarHBondContact O-CB 3.3Å; Y238-A292 HydrophobicContact CD2-CB 4.39Å; Y238-A292 HydrophobicContact CE2-CB 3.79Å; Y238-A292 PolarHBondContact N-O 3.39Å; Y238-A292 PolarHBondContact O-N 3.2Å; Y238-R294 HydrophobicContact CE1-CG 4.17Å
239R80.1Confident79.1Confident4 Ų449.9 Ų49.92%0.01524%0.237CC..EExtended strand (participates in β ladder)trans-119.6146.8176.3-171.1-179.6179.3-178.77.2109.9D77 F81 P82 P84 Y170 P172 W241 S288 A290D77-R239 VanDerWaalsContact CB-NH1 3.26Å; D77-R239 IonicContact OD2-NH1 3.36Å; D77-R239 PolarHBondContact OD2-NH1 2.95Å; F81-R239 HydrophobicContact CB-CB 3.76Å; F81-R239 HydrophobicContact CG-CB 4.4Å; P82-R239 PolarHBondContact O-N 2.8Å; P84-R239 WeakPolarHBondContact CD-O 3.5Å; Y170-R239 PolarHBondContact OH-NH1 2.85Å; Y170-R239 PolarHBondContact OH-NH2 3.42Å; P172-R239 HydrophobicContact CG-CG 4.4Å; R239-W241 HydrophobicContact CB-CE3 4.22Å; R239-W241 HydrophobicContact CB-CZ3 4.24Å; R239-W241 VanDerWaalsContact O-CZ3 3.26Å; R239-W241 WeakPolarHBondContact O-CZ3 3.16Å; R239-S288 PolarHBondContact NE-O 3.12Å; R239-S288 PolarHBondContact NH2-O 3.08Å; R239-A290 WeakPolarHBondContact CG-O 3.22Å
240F75.9Confident79.1Confident1 Ų143.4 Ų43.40%0.00421%0.21CC..EExtended strand (participates in β ladder)trans-94.2134.5172.8-59.1-100.9000109.1P84 Y238 M247 D250 I257 E287 A290 A292P84-F240 HydrophobicContact CB-CE1 4.29Å; P84-F240 HydrophobicContact CG-CD1 3.51Å; P84-F240 HydrophobicContact CG-CE1 3.27Å; P84-F240 HydrophobicContact CG-CE2 4.35Å; P84-F240 HydrophobicContact CG-CG 4.16Å; P84-F240 HydrophobicContact CG-CZ 3.75Å; Y238-F240 HydrophobicContact CD2-CE2 4.07Å; Y238-F240 HydrophobicContact CD2-CZ 4.19Å; Y238-F240 AromaticContact CE2-CE2 3.96Å; Y238-F240 HydrophobicContact CE2-CE2 3.96Å; Y238-F240 AromaticContact CE2-CZ 3.75Å; Y238-F240 HydrophobicContact CE2-CZ 3.75Å; F240-M247 HydrophobicContact CB-CG 4.09Å; F240-M247 HydrophobicContact CD1-CB 4.28Å; F240-M247 HydrophobicContact CD1-CG 3.49Å; F240-M247 VanDerWaalsContact CD1-CG 3.49Å; F240-M247 HydrophobicContact CD2-CG 4.47Å; F240-M247 HydrophobicContact CE1-CB 4.32Å; F240-M247 HydrophobicContact CE1-CG 3.97Å; F240-M247 HydrophobicContact CG-CG 3.77Å; F240-D250 HydrophobicContact CE1-CB 3.71Å; F240-D250 HydrophobicContact CZ-CB 3.66Å; F240-I257 HydrophobicContact CE2-CB 4.3Å; F240-I257 HydrophobicContact CE2-CD1 4.19Å; F240-I257 HydrophobicContact CE2-CG2 3.97Å; F240-I257 HydrophobicContact CZ-CD1 4.28Å; F240-I257 HydrophobicContact CZ-CG2 3.86Å; F240-E287 CarbonylContact C-O 3.59Å; F240-A290 HydrophobicContact CB-CB 4.01Å; F240-A290 HydrophobicContact CD2-CB 3.66Å; F240-A290 WeakPolarHBondContact CD2-O 3.4Å; F240-A290 HydrophobicContact CE2-CB 4.44Å; F240-A290 HydrophobicContact CG-CB 4.07Å; F240-A290 PolarHBondContact N-O 3.31Å; F240-A292 HydrophobicContact CE2-CB 4.21Å
241W65.6Low79Confident58 Ų5844.9 Ų44.922%0.2222%0.217CC..  trans-140.21171.860.286.5000113.6F81 P82 H83 E86 R239F81-W241 WeakPolarHBondContact O-CH2 3.3Å; F81-W241 WeakPolarHBondContact O-CZ3 3.5Å; P82-W241 VanDerWaalsContact C-CZ3 3.41Å; H83-W241 VanDerWaalsContact CA-CH2 3.49Å; H83-W241 HydrophobicContact CB-CE3 4.47Å; H83-W241 HydrophobicContact CB-CH2 3.5Å; H83-W241 VanDerWaalsContact CB-CH2 3.5Å; H83-W241 HydrophobicContact CB-CZ2 3.46Å; H83-W241 VanDerWaalsContact CB-CZ2 3.46Å; H83-W241 HydrophobicContact CB-CZ3 3.98Å; H83-W241 AromaticContact CD2-CD2 3.59Å; H83-W241 AromaticContact CD2-CE2 3.69Å; H83-W241 AromaticContact CD2-CE3 3.81Å; E86-W241 WeakPolarHBondContact OE1-CH2 3.35Å; R239-W241 HydrophobicContact CB-CE3 4.22Å; R239-W241 HydrophobicContact CB-CZ3 4.24Å; R239-W241 VanDerWaalsContact O-CZ3 3.26Å; R239-W241 WeakPolarHBondContact O-CZ3 3.16Å
242L54.4Low78.8Confident113 Ų11346.7 Ų46.759%0.59222%0.224SC*.SBendtrans-119.640.1-175.3-65.9171.2000114.4
243G64.6Low78.5Confident24 Ų2447.3 Ų47.325%0.24723%0.228CC..  trans86.6170.816200000117K245 S246G243-K245 VanDerWaalsContact C-N 3.34Å; G243-K245 PolarHBondContact O-N 3.25Å; G243-S246 PolarHBondContact O-N 3.37Å
244E75.1Confident78.5Confident144 Ų14445.6 Ų45.667%0.67322%0.22SC*.Hα-helixtrans-54.1-39.1-168-174.6-179.3167.500114.4S246 M247 M248E244-S246 PolarHBondContact O-N 3.14Å; E244-M247 WeakPolarHBondContact O-CB 3.46Å; E244-M247 PolarHBondContact O-N 3.4Å; E244-M248 HydrophobicContact CG-CG 4.25Å; E244-M248 HydrophobicContact CG-SD 3.94Å; E244-M248 WeakPolarHBondContact O-CG 3.44Å; E244-M248 PolarHBondContact O-N 3Å
245K77.1Confident78.9Confident171 Ų17145.3 Ų45.374%0.74322%0.218SC*.Hα-helixtrans-63.4-41.2-175.8-73.5-171.8177.1-176.80113.4G243 M247 M248 K249G243-K245 VanDerWaalsContact C-N 3.34Å; G243-K245 PolarHBondContact O-N 3.25Å; K245-M247 VanDerWaalsContact C-N 3.32Å; K245-M248 PolarHBondContact O-N 3.39Å; K245-K249 WeakPolarHBondContact O-CB 3.37Å; K245-K249 PolarHBondContact O-N 3.42Å
246S77.2Confident80Confident20 Ų2044.8 Ų44.814%0.1422%0.215CC..Hα-helixtrans-67.8-35.7178.4-62.10000111D85 G243 E244 D250D85-S246 PolarHBondContact OD2-OG 3.14Å; G243-S246 PolarHBondContact O-N 3.37Å; E244-S246 PolarHBondContact O-N 3.14Å; S246-D250 WeakPolarHBondContact O-CB 3.25Å; S246-D250 PolarHBondContact O-N 3.17Å
247M83.3Confident81Confident22 Ų2245.8 Ų45.811%0.10822%0.22CC..Hα-helixtrans-64.3-48.1172.5-65.7167.162.500111.7F240 E244 K245 K249 D250 I251 I257 I286 E287 A290F240-M247 HydrophobicContact CB-CG 4.09Å; F240-M247 HydrophobicContact CD1-CB 4.28Å; F240-M247 HydrophobicContact CD1-CG 3.49Å; F240-M247 VanDerWaalsContact CD1-CG 3.49Å; F240-M247 HydrophobicContact CD2-CG 4.47Å; F240-M247 HydrophobicContact CE1-CB 4.32Å; F240-M247 HydrophobicContact CE1-CG 3.97Å; F240-M247 HydrophobicContact CG-CG 3.77Å; E244-M247 WeakPolarHBondContact O-CB 3.46Å; E244-M247 PolarHBondContact O-N 3.4Å; K245-M247 VanDerWaalsContact C-N 3.32Å; M247-K249 VanDerWaalsContact C-N 3.31Å; M247-K249 PolarHBondContact O-N 3.03Å; M247-D250 PolarHBondContact O-N 3.38Å; M247-I251 WeakPolarHBondContact O-CB 3.28Å; M247-I251 VanDerWaalsContact O-CG1 3.22Å; M247-I251 WeakPolarHBondContact O-CG1 3.13Å; M247-I251 PolarHBondContact O-N 3.47Å; M247-I257 HydrophobicContact CB-CD1 3.79Å; M247-I257 HydrophobicContact CE-CD1 3.61Å; M247-I257 HydrophobicContact CG-CD1 3.89Å; M247-I286 HydrophobicContact CE-CG2 3.74Å; M247-E287 HydrophobicContact SD-CB 4.11Å; M247-A290 HydrophobicContact CE-CB 3.83Å; M247-A290 HydrophobicContact CG-CB 4.4Å; M247-A290 HydrophobicContact SD-CB 4.13Å
248M85.1Confident81.6Confident71 Ų7144 Ų4435%0.3521%0.214SC..Hα-helixtrans-58.8-43.7177.2-68.217375.700111.5L96 E244 K245 I251 Y252L96-M248 HydrophobicContact CD1-CB 3.82Å; E244-M248 HydrophobicContact CG-CG 4.25Å; E244-M248 HydrophobicContact CG-SD 3.94Å; E244-M248 WeakPolarHBondContact O-CG 3.44Å; E244-M248 PolarHBondContact O-N 3Å; K245-M248 PolarHBondContact O-N 3.39Å; M248-I251 PolarHBondContact O-N 2.77Å; M248-Y252 VanDerWaalsContact O-CB 3.28Å; M248-Y252 WeakPolarHBondContact O-CB 3.48Å; M248-Y252 PolarHBondContact O-N 3.36Å
249K82.6Confident82Confident40 Ų4046.1 Ų46.117%0.17423%0.232CC..Hα-helixtrans-60.6-47176.4-176-179.5178.6177.30111.9E90 L96 K245 M247 I251 Y252 L253E90-K249 PolarHBondContact O-NZ 3.48Å; L96-K249 HydrophobicContact CD1-CB 4.22Å; L96-K249 HydrophobicContact CD2-CB 4.35Å; K245-K249 WeakPolarHBondContact O-CB 3.37Å; K245-K249 PolarHBondContact O-N 3.42Å; M247-K249 VanDerWaalsContact C-N 3.31Å; M247-K249 PolarHBondContact O-N 3.03Å; K249-I251 VanDerWaalsContact C-N 3.35Å; K249-Y252 WeakPolarHBondContact O-CB 3.41Å; K249-Y252 PolarHBondContact O-N 3.47Å; K249-L253 HydrophobicContact CG-CD1 3.93Å; K249-L253 WeakPolarHBondContact O-CG 3.41Å; K249-L253 PolarHBondContact O-N 2.75Å
250D85.6Confident82.1Confident4 Ų446.4 Ų46.42%0.02124%0.235CC..Hα-helixtrans-67.4-37.5-179-157.378.6000111.7R137 Y238 F240 S246 M247 L253 Y254 G255R137-D250 IonicContact CZ-OD2 3.91Å; R137-D250 IonicContact NH1-OD2 2.9Å; R137-D250 PolarHBondContact NH1-OD2 2.9Å; R137-D250 IonicContact NH2-OD2 2.77Å; R137-D250 PolarHBondContact NH2-OD2 3.15Å; Y238-D250 WeakPolarHBondContact CE2-OD2 3.31Å; Y238-D250 PolarHBondContact OH-OD1 2.81Å; Y238-D250 PolarHBondContact OH-OD2 2.85Å; F240-D250 HydrophobicContact CE1-CB 3.71Å; F240-D250 HydrophobicContact CZ-CB 3.66Å; S246-D250 WeakPolarHBondContact O-CB 3.25Å; S246-D250 PolarHBondContact O-N 3.17Å; M247-D250 PolarHBondContact O-N 3.38Å; D250-L253 PolarHBondContact O-N 3.16Å; D250-Y254 PolarHBondContact O-N 3.39Å; D250-Y254 VanDerWaalsContact OD1-CD2 3.31Å; D250-Y254 WeakPolarHBondContact OD1-CD2 3.14Å; D250-G255 PolarHBondContact O-N 3.21Å
251I91.1Very high82.2Confident45 Ų4549.1 Ų49.123%0.23125%0.248CC..Hα-helixtrans-62.7-42.9172.5-68165.1000111.3F100 W106 M247 M248 K249 G255 I257F100-I251 HydrophobicContact CD1-CG2 3.72Å; F100-I251 HydrophobicContact CE1-CG2 3.71Å; F100-I251 WeakPolarHBondContact CE1-O 3.22Å; W106-I251 WeakPolarHBondContact CH2-O 3.26Å; M247-I251 WeakPolarHBondContact O-CB 3.28Å; M247-I251 VanDerWaalsContact O-CG1 3.22Å; M247-I251 WeakPolarHBondContact O-CG1 3.13Å; M247-I251 PolarHBondContact O-N 3.47Å; M248-I251 PolarHBondContact O-N 2.77Å; K249-I251 VanDerWaalsContact C-N 3.35Å; I251-G255 WeakPolarHBondContact CA-O 3.41Å; I251-G255 VanDerWaalsContact O-CA 3.3Å; I251-G255 WeakPolarHBondContact O-CA 3.47Å; I251-G255 PolarHBondContact O-N 3.32Å; I251-G255 VanDerWaalsContact O-N 3.07Å; I251-I257 HydrophobicContact CD1-CD1 3.83Å; I251-I257 HydrophobicContact CD1-CG1 3.98Å; I251-I257 HydrophobicContact CG1-CD1 4.05Å; I251-I257 HydrophobicContact CG1-CG1 4.01Å; I251-I257 HydrophobicContact CG1-CG2 3.99Å
252Y88.8Confident82.7Confident76 Ų7649.2 Ų49.230%0.29826%0.255SS..Hα-helixtrans-64.5-39.6179.8-178.7-102.6000112.7I94 L96 P97 F100 W106 M248 K249I94-Y252 HydrophobicContact CG2-CD1 3.93Å; I94-Y252 HydrophobicContact CG2-CE1 3.8Å; L96-Y252 HydrophobicContact CD2-CD1 4Å; L96-Y252 HydrophobicContact CD2-CG 3.88Å; P97-Y252 HydrophobicContact CG-CD2 4.18Å; P97-Y252 HydrophobicContact CG-CE2 4.01Å; F100-Y252 AromaticContact CD2-CD2 3.45Å; F100-Y252 HydrophobicContact CD2-CD2 3.45Å; F100-Y252 VanDerWaalsContact CD2-CD2 3.45Å; F100-Y252 AromaticContact CD2-CE2 3.94Å; F100-Y252 HydrophobicContact CD2-CE2 3.94Å; F100-Y252 AromaticContact CE2-CD2 3.38Å; F100-Y252 HydrophobicContact CE2-CD2 3.38Å; F100-Y252 AromaticContact CE2-CE2 3.82Å; F100-Y252 HydrophobicContact CE2-CE2 3.82Å; F100-Y252 HydrophobicContact CE2-CG 4.32Å; F100-Y252 HydrophobicContact CG-CD2 4.2Å; F100-Y252 HydrophobicContact CZ-CD2 4.1Å; W106-Y252 VanDerWaalsContact CH2-O 3.24Å; W106-Y252 WeakPolarHBondContact CH2-O 3.27Å; M248-Y252 VanDerWaalsContact O-CB 3.28Å; M248-Y252 WeakPolarHBondContact O-CB 3.48Å; M248-Y252 PolarHBondContact O-N 3.36Å; K249-Y252 WeakPolarHBondContact O-CB 3.41Å; K249-Y252 PolarHBondContact O-N 3.47Å
253L85.5Confident83.9Confident39 Ų3946.2 Ų46.220%0.20424%0.241CC..Hα-helixtrans-87.1-44-175.8-67.7174.6000113.4E90 I94 K249 D250E90-L253 HydrophobicContact CB-CD1 4.37Å; I94-L253 HydrophobicContact CD1-CD1 3.92Å; I94-L253 HydrophobicContact CD1-CD2 3.89Å; I94-L253 HydrophobicContact CD1-CG 4.34Å; K249-L253 HydrophobicContact CG-CD1 3.93Å; K249-L253 WeakPolarHBondContact O-CG 3.41Å; K249-L253 PolarHBondContact O-N 2.75Å; D250-L253 PolarHBondContact O-N 3.16Å
254Y88Confident84.7Confident35 Ų3548.7 Ų48.714%0.13724%0.243CC..Hα-helixtrans-119.4-10.1-166.2-52.4-58.8000113.5E90 R137 D250 R294E90-Y254 PolarHBondContact OE1-OH 2.73Å; E90-Y254 PolarHBondContact OE2-OH 3.15Å; R137-Y254 WeakPolarHBondContact CG-O 3.3Å; D250-Y254 PolarHBondContact O-N 3.39Å; D250-Y254 VanDerWaalsContact OD1-CD2 3.31Å; D250-Y254 WeakPolarHBondContact OD1-CD2 3.14Å; Y254-R294 VanDerWaalsContact CE2-CZ 3.46Å; Y254-R294 VanDerWaalsContact CE2-NH2 3.29Å; Y254-R294 HydrophobicContact CG-CG 4.42Å; Y254-R294 VanDerWaalsContact OH-CZ 3.28Å; Y254-R294 PolarHBondContact OH-NH1 2.87Å; Y254-R294 PolarHBondContact OH-NH2 2.86Å
255G92.9Very high84.9Confident0 Ų044.3 Ų44.30%023%0.228CC..  trans98.6-168.3178.300000114.6R137 D250 I251R137-G255 PolarHBondContact NH2-O 2.97Å; D250-G255 PolarHBondContact O-N 3.21Å; I251-G255 WeakPolarHBondContact CA-O 3.41Å; I251-G255 VanDerWaalsContact O-CA 3.3Å; I251-G255 WeakPolarHBondContact O-CA 3.47Å; I251-G255 PolarHBondContact O-N 3.32Å; I251-G255 VanDerWaalsContact O-N 3.07Å
256P96.7Very high85.1Confident24 Ų2438.3 Ų38.316%0.15620%0.204CC..  trans-50.2153.8-170.6-29.437000115.1I113 V133 D136 R137I113-P256 HydrophobicContact CG2-CG 4.15Å; V133-P256 VanDerWaalsContact CG1-O 3.28Å; V133-P256 WeakPolarHBondContact CG1-O 3.28Å; V133-P256 HydrophobicContact CG2-CB 4.37Å; D136-P256 HydrophobicContact CB-CG 4.15Å; D136-P256 WeakPolarHBondContact OD2-CG 3.43Å; R137-P256 PolarHBondContact NE-O 2.9Å; R137-P256 PolarHBondContact NH2-O 3.3Å
257I94.4Very high85.5Confident24 Ų2440.6 Ų40.612%0.12321%0.212CC..  trans-126.2159.1177.363.3-180000110.1F240 M247 I251 A290 A292F240-I257 HydrophobicContact CE2-CB 4.3Å; F240-I257 HydrophobicContact CE2-CD1 4.19Å; F240-I257 HydrophobicContact CE2-CG2 3.97Å; F240-I257 HydrophobicContact CZ-CD1 4.28Å; F240-I257 HydrophobicContact CZ-CG2 3.86Å; M247-I257 HydrophobicContact CB-CD1 3.79Å; M247-I257 HydrophobicContact CE-CD1 3.61Å; M247-I257 HydrophobicContact CG-CD1 3.89Å; I251-I257 HydrophobicContact CD1-CD1 3.83Å; I251-I257 HydrophobicContact CD1-CG1 3.98Å; I251-I257 HydrophobicContact CG1-CD1 4.05Å; I251-I257 HydrophobicContact CG1-CG1 4.01Å; I251-I257 HydrophobicContact CG1-CG2 3.99Å; I257-A290 HydrophobicContact CD1-CB 4.12Å; I257-A292 HydrophobicContact CB-CB 4.24Å; I257-A292 HydrophobicContact CG2-CB 3.84Å
258V92.4Very high85.6Confident8 Ų840 Ų405%0.04821%0.209CC..EExtended strand (participates in β ladder)trans-83.3138.7168.5177.50000108.2S129 A130 V133 P171 F175 A290 S291S129-V258 WeakPolarHBondContact O-CG2 3.1Å; A130-V258 HydrophobicContact CB-CG2 4.42Å; V133-V258 HydrophobicContact CB-CG2 4.11Å; V133-V258 HydrophobicContact CG2-CG2 3.72Å; P171-V258 HydrophobicContact CB-CB 4.44Å; P171-V258 HydrophobicContact CB-CG1 3.78Å; P171-V258 HydrophobicContact CG-CG1 4Å; F175-V258 HydrophobicContact CE2-CB 4.23Å; F175-V258 HydrophobicContact CE2-CG2 3.86Å; F175-V258 HydrophobicContact CZ-CB 4.48Å; F175-V258 HydrophobicContact CZ-CG2 3.72Å; V258-A290 CarbonylContact O-C 3.56Å; V258-A290 WeakPolarHBondContact O-CA 3.34Å; V258-A290 WeakPolarHBondContact O-CB 3.34Å; V258-S291 PolarHBondContact N-O 3.18Å; V258-S291 PolarHBondContact O-N 2.99Å
259A86.8Confident85.8Confident46 Ų4636.6 Ų36.638%0.3819%0.192SC..EExtended strand (participates in β ladder)trans-139121179.900000109.3I286A259-I286 HydrophobicContact CB-CG2 3.3Å
260G81.8Confident86.2Confident9 Ų938.2 Ų38.29%0.09320%0.198CC..  trans-95151170.500000112.1I286 Y289G260-I286 WeakPolarHBondContact O-CA 3.35Å; G260-Y289 PolarHBondContact N-O 3.07Å; G260-Y289 WeakPolarHBondContact O-CB 3.33Å
261F77.5Confident86.4Confident59 Ų5942.8 Ų42.826%0.25922%0.217SC..  trans-153.615817161-83.4000110.5V263 F267 I277 I286F261-V263 HydrophobicContact CD2-CG2 4.44Å; F261-V263 HydrophobicContact CE2-CG2 4.01Å; F261-V263 HydrophobicContact CZ-CG2 4.44Å; F261-V263 PolarHBondContact O-N 3.21Å; F261-F267 HydrophobicContact CE2-CD1 4.39Å; F261-F267 HydrophobicContact CE2-CD2 4.39Å; F261-F267 HydrophobicContact CE2-CE1 4.33Å; F261-F267 HydrophobicContact CE2-CE2 4.34Å; F261-F267 HydrophobicContact CE2-CG 4.42Å; F261-F267 HydrophobicContact CE2-CZ 4.3Å; F261-F267 HydrophobicContact CZ-CD1 4.38Å; F261-F267 AromaticContact CZ-CE1 3.87Å; F261-F267 HydrophobicContact CZ-CE1 3.87Å; F261-F267 HydrophobicContact CZ-CE2 4.03Å; F261-F267 AromaticContact CZ-CZ 3.68Å; F261-F267 HydrophobicContact CZ-CZ 3.68Å; F261-I277 HydrophobicContact CB-CD1 4.09Å; F261-I277 HydrophobicContact CD2-CD1 3.62Å; F261-I277 HydrophobicContact CE2-CD1 4.41Å; F261-I277 HydrophobicContact CG-CD1 4.12Å; F261-I286 HydrophobicContact CB-CG1 3.82Å; F261-I286 HydrophobicContact CD1-CG1 4.39Å; F261-I286 HydrophobicContact CG-CG1 4.42Å
262T76.1Confident86.3Confident60 Ų6045.3 Ų45.337%0.36823%0.228SC..  trans-66117.8173.3-52.60000110.1L70 Y264L70-T262 WeakPolarHBondContact CD1-OG1 3.43Å; T262-Y264 HydrophobicContact CG2-CE2 4.23Å; T262-Y264 WeakPolarHBondContact O-CD2 3.43Å; T262-Y264 PolarHBondContact O-N 3.42Å
263V80Confident86.1Confident50 Ų5043.7 Ų43.730%0.30324%0.235SC..  trans-81.6109178.1179.10000109.6L66 F261 F267L66-V263 HydrophobicContact CD1-CB 4.06Å; L66-V263 HydrophobicContact CD1-CG1 4.48Å; L66-V263 HydrophobicContact CD1-CG2 4.47Å; L66-V263 HydrophobicContact CD2-CB 4.29Å; L66-V263 HydrophobicContact CD2-CG2 3.93Å; F261-V263 HydrophobicContact CD2-CG2 4.44Å; F261-V263 HydrophobicContact CE2-CG2 4.01Å; F261-V263 HydrophobicContact CZ-CG2 4.44Å; F261-V263 PolarHBondContact O-N 3.21Å; V263-F267 HydrophobicContact CG1-CB 4.21Å; V263-F267 HydrophobicContact CG1-CD1 3.92Å; V263-F267 HydrophobicContact CG1-CG 4.46Å
264Y81Confident85.8Confident75 Ų7547.5 Ų47.529%0.29426%0.255SS..  trans-80.6151170.6-69.2-79.5000111.2T262 D266 F267 I277 E283T262-Y264 HydrophobicContact CG2-CE2 4.23Å; T262-Y264 WeakPolarHBondContact O-CD2 3.43Å; T262-Y264 PolarHBondContact O-N 3.42Å; Y264-D266 WeakPolarHBondContact CB-OD1 3.3Å; Y264-D266 PolarHBondContact O-N 2.74Å; Y264-D266 VanDerWaalsContact O-N 3.09Å; Y264-F267 VanDerWaalsContact O-CB 3.26Å; Y264-F267 WeakPolarHBondContact O-CB 3.47Å; Y264-F267 PolarHBondContact O-N 3.45Å; Y264-I277 HydrophobicContact CD2-CG2 3.93Å; Y264-I277 HydrophobicContact CE2-CG2 3.49Å; Y264-I277 VanDerWaalsContact CE2-CG2 3.49Å; Y264-E283 PolarHBondContact OH-OE1 3.41Å; Y264-E283 PolarHBondContact OH-OE2 3.09Å
265S79.3Confident85.3Confident52 Ų5247.6 Ų47.636%0.36426%0.256SS..G310 helixtrans-60-25.6-172.967.40000114.2H25 M268 Y269H25-S265 WeakPolarHBondContact NE2-CB 3.28Å; H25-S265 PolarHBondContact NE2-OG 2.83Å; S265-M268 WeakPolarHBondContact O-CE 3.48Å; S265-Y269 WeakPolarHBondContact O-CE2 3.43Å
266D80.8Confident84.2Confident45 Ų4556.8 Ų56.824%0.24129%0.291CS..G310 helixtrans-71.6-26.4177.361.9-23.5000113.3I29 W46 Y264 M268 Y269I29-D266 HydrophobicContact CD1-CB 4.06Å; W46-D266 HydrophobicContact CH2-CB 4.38Å; Y264-D266 WeakPolarHBondContact CB-OD1 3.3Å; Y264-D266 PolarHBondContact O-N 2.74Å; Y264-D266 VanDerWaalsContact O-N 3.09Å; D266-M268 PolarHBondContact O-N 3.07Å; D266-Y269 PolarHBondContact O-N 2.91Å; D266-Y269 VanDerWaalsContact O-N 3.15Å
267F85.7Confident82.6Confident69 Ų6958.3 Ų58.330%0.30330%0.297SS..G310 helixtrans-59.2-32.9178.8-176.8-108.9000112.8F261 V263 Y264 Y269 Y270 F275F261-F267 HydrophobicContact CE2-CD1 4.39Å; F261-F267 HydrophobicContact CE2-CD2 4.39Å; F261-F267 HydrophobicContact CE2-CE1 4.33Å; F261-F267 HydrophobicContact CE2-CE2 4.34Å; F261-F267 HydrophobicContact CE2-CG 4.42Å; F261-F267 HydrophobicContact CE2-CZ 4.3Å; F261-F267 HydrophobicContact CZ-CD1 4.38Å; F261-F267 AromaticContact CZ-CE1 3.87Å; F261-F267 HydrophobicContact CZ-CE1 3.87Å; F261-F267 HydrophobicContact CZ-CE2 4.03Å; F261-F267 AromaticContact CZ-CZ 3.68Å; F261-F267 HydrophobicContact CZ-CZ 3.68Å; V263-F267 HydrophobicContact CG1-CB 4.21Å; V263-F267 HydrophobicContact CG1-CD1 3.92Å; V263-F267 HydrophobicContact CG1-CG 4.46Å; Y264-F267 VanDerWaalsContact O-CB 3.26Å; Y264-F267 WeakPolarHBondContact O-CB 3.47Å; Y264-F267 PolarHBondContact O-N 3.45Å; F267-Y269 PolarHBondContact O-N 3.24Å; F267-Y270 VanDerWaalsContact O-CB 3.26Å; F267-Y270 WeakPolarHBondContact O-CB 2.97Å; F267-Y270 PolarHBondContact O-N 2.91Å; F267-F275 HydrophobicContact CB-CE1 4.13Å; F267-F275 HydrophobicContact CB-CE2 4.33Å; F267-F275 HydrophobicContact CB-CZ 3.8Å; F267-F275 AromaticContact CD2-CD1 3.67Å; F267-F275 HydrophobicContact CD2-CD1 3.67Å; F267-F275 HydrophobicContact CD2-CD2 4.25Å; F267-F275 AromaticContact CD2-CE1 3.66Å; F267-F275 HydrophobicContact CD2-CE1 3.66Å; F267-F275 HydrophobicContact CD2-CE2 4.25Å; F267-F275 AromaticContact CD2-CG 3.98Å; F267-F275 HydrophobicContact CD2-CG 3.98Å; F267-F275 AromaticContact CD2-CZ 3.97Å; F267-F275 HydrophobicContact CD2-CZ 3.97Å; F267-F275 HydrophobicContact CE2-CD1 4.23Å; F267-F275 HydrophobicContact CE2-CG 4.45Å; F267-F275 HydrophobicContact CG-CE1 4.34Å; F267-F275 HydrophobicContact CG-CZ 4.4Å
268M85.7Confident80.7Confident9 Ų965.2 Ų65.24%0.04432%0.321CS..G310 helixtrans-64.4-14-179.3-53.3-176.8-6900113.6F21 Y22 N51 F54 I62 S265 D266F21-M268 HydrophobicContact CE1-CE 4.22Å; Y22-M268 HydrophobicContact CD2-CB 4.37Å; Y22-M268 HydrophobicContact CD2-CE 4.4Å; Y22-M268 HydrophobicContact CE2-CB 3.71Å; Y22-M268 PolarHBondContact OH-O 3.25Å; N51-M268 PolarHBondContact ND2-O 2.84Å; F54-M268 HydrophobicContact CD2-CB 4.17Å; F54-M268 HydrophobicContact CE2-CB 4.16Å; I62-M268 HydrophobicContact CB-SD 4.4Å; I62-M268 HydrophobicContact CD1-CE 4.3Å; I62-M268 HydrophobicContact CD1-SD 3.57Å; I62-M268 VanDerWaalsContact CD1-SD 3.57Å; I62-M268 HydrophobicContact CG1-SD 4.33Å; I62-M268 HydrophobicContact CG2-SD 3.43Å; I62-M268 WeakPolarHBondContact CG2-SD 3.31Å; S265-M268 WeakPolarHBondContact O-CE 3.48Å; D266-M268 PolarHBondContact O-N 3.07Å
269Y89.9Confident78.5Confident0 Ų073 Ų730%035%0.35CS..G310 helixtrans-103.41.5177.9-49.6-75.7000112.6Y22 H25 F26 I29 Y48 G49 L50 S265 D266 F267 K271Y22-Y269 HydrophobicContact CD2-CD1 4.4Å; Y22-Y269 AromaticContact CD2-CE1 3.53Å; Y22-Y269 HydrophobicContact CD2-CE1 3.53Å; Y22-Y269 AromaticContact CD2-CZ 3.75Å; Y22-Y269 WeakPolarHBondContact CD2-OH 3.13Å; Y22-Y269 HydrophobicContact CE1-CE1 4.19Å; Y22-Y269 AromaticContact CE2-CD1 3.52Å; Y22-Y269 HydrophobicContact CE2-CD1 3.52Å; Y22-Y269 AromaticContact CE2-CE1 3.07Å; Y22-Y269 HydrophobicContact CE2-CE1 3.07Å; Y22-Y269 HydrophobicContact CE2-CE2 4.44Å; Y22-Y269 HydrophobicContact CE2-CG 4.39Å; Y22-Y269 AromaticContact CE2-CZ 3.6Å; Y22-Y269 HydrophobicContact CG-CE1 4.24Å; Y22-Y269 AromaticContact CZ-CD1 3.58Å; Y22-Y269 AromaticContact CZ-CE1 3.45Å; Y22-Y269 VanDerWaalsContact CZ-CE1 3.45Å; Y22-Y269 PolarHBondContact O-OH 3.14Å; Y22-Y269 WeakPolarHBondContact OH-CD1 3.34Å; H25-Y269 WeakPolarHBondContact CB-OH 3.37Å; H25-Y269 AromaticContact CD2-CE2 3.85Å; H25-Y269 PolarHBondContact CD2-OH 3.17Å; F26-Y269 HydrophobicContact CB-CD1 4.14Å; F26-Y269 HydrophobicContact CB-CE1 3.63Å; F26-Y269 AromaticContact CD2-CD1 3.37Å; F26-Y269 HydrophobicContact CD2-CD1 3.37Å; F26-Y269 AromaticContact CD2-CE1 3.8Å; F26-Y269 HydrophobicContact CD2-CE1 3.8Å; F26-Y269 AromaticContact CD2-CG 3.92Å; F26-Y269 HydrophobicContact CD2-CG 3.92Å; F26-Y269 HydrophobicContact CE2-CD1 4.17Å; F26-Y269 HydrophobicContact CG-CD1 4.16Å; F26-Y269 HydrophobicContact CG-CE1 4.16Å; I29-Y269 HydrophobicContact CG1-CD2 4.13Å; I29-Y269 HydrophobicContact CG1-CE2 3.83Å; I29-Y269 HydrophobicContact CG2-CD2 4.36Å; Y48-Y269 CarbonylContact C-O 3.38Å; Y48-Y269 WeakPolarHBondContact CA-O 3.49Å; Y48-Y269 WeakPolarHBondContact CB-O 3.3Å; G49-Y269 PolarHBondContact N-O 3.16Å; G49-Y269 CarbonylContact O-C 3.51Å; G49-Y269 WeakPolarHBondContact O-CA 3.26Å; G49-Y269 VanDerWaalsContact O-O 3.13Å; L50-Y269 HydrophobicContact CD2-CD1 4.42Å; L50-Y269 HydrophobicContact CD2-CE1 4.25Å; S265-Y269 WeakPolarHBondContact O-CE2 3.43Å; D266-Y269 PolarHBondContact O-N 2.91Å; D266-Y269 VanDerWaalsContact O-N 3.15Å; F267-Y269 PolarHBondContact O-N 3.24Å; Y269-K271 PolarHBondContact O-N 3Å
270Y90.7Very high76.4Confident74 Ų7472.3 Ų72.329%0.2935%0.347SS..EExtended strand (participates in β ladder)trans-60.7134.8178.1173.1-96.9000111.4W46 N51 F267 Q272 G273 F275W46-Y270 HydrophobicContact CB-CD2 4.07Å; W46-Y270 HydrophobicContact CB-CE2 4.02Å; W46-Y270 HydrophobicContact CD2-CD2 4.34Å; W46-Y270 AromaticContact CE3-CD2 3.8Å; W46-Y270 HydrophobicContact CE3-CD2 3.8Å; W46-Y270 HydrophobicContact CE3-CG 4.47Å; W46-Y270 HydrophobicContact CG-CD2 4.46Å; N51-Y270 PolarHBondContact ND2-O 2.74Å; F267-Y270 VanDerWaalsContact O-CB 3.26Å; F267-Y270 WeakPolarHBondContact O-CB 2.97Å; F267-Y270 PolarHBondContact O-N 2.91Å; Y270-Q272 WeakPolarHBondContact OH-CA 3.42Å; Y270-G273 WeakPolarHBondContact CE2-O 3.48Å; Y270-G273 PolarHBondContact OH-N 2.89Å; Y270-G273 VanDerWaalsContact OH-N 3.14Å; Y270-G273 PolarHBondContact OH-O 2.74Å; Y270-F275 HydrophobicContact CD2-CB 3.86Å; Y270-F275 HydrophobicContact CD2-CD2 4.15Å; Y270-F275 HydrophobicContact CD2-CG 4.4Å; Y270-F275 HydrophobicContact CE2-CB 4.02Å
271K88.8Confident74.3Confident99 Ų9982 Ų8243%0.4339%0.387SS..EExtended strand (participates in β ladder)trans-118.7-44.1175.3-71.5-69.4-172.8-176.80112.9K47 L50 N51 Y269K47-K271 PolarHBondContact O-N 3.4Å; L50-K271 WeakPolarHBondContact O-CE 3.38Å; L50-K271 PolarHBondContact O-NZ 3.16Å; N51-K271 WeakPolarHBondContact OD1-CD 3.37Å; N51-K271 WeakPolarHBondContact OD1-CE 3.27Å; N51-K271 PolarHBondContact OD1-NZ 2.97Å; Y269-K271 PolarHBondContact O-N 3Å
272Q89.5Confident72.5Confident98 Ų9886.9 Ų86.946%0.45842%0.416SS..EExtended strand (participates in β ladder)trans-167.2158.6-178.452.9164.6100.400111.5W46 K47 Y270W46-Q272 CarbonylContact C-O 3.57Å; W46-Q272 VanDerWaalsContact CA-O 3.25Å; W46-Q272 WeakPolarHBondContact CA-O 3.04Å; W46-Q272 WeakPolarHBondContact CB-O 3.46Å; K47-Q272 HydrophobicContact CB-CG 3.64Å; K47-Q272 HydrophobicContact CD-CG 3.69Å; K47-Q272 VanDerWaalsContact CE-CD 3.48Å; K47-Q272 HydrophobicContact CG-CG 3.7Å; K47-Q272 PolarHBondContact N-O 2.88Å; K47-Q272 VanDerWaalsContact NZ-NE2 3.13Å; K47-Q272 VanDerWaalsContact NZ-OE1 3.1Å; K47-Q272 PolarHBondContact O-N 2.87Å; Y270-Q272 WeakPolarHBondContact OH-CA 3.42Å
273G85.3Confident70.9Confident42 Ų4288 Ų8843%0.43342%0.417SS..EExtended strand (participates in β ladder)trans104.9-163.6174.700000112.8Y270 F275Y270-G273 WeakPolarHBondContact CE2-O 3.48Å; Y270-G273 PolarHBondContact OH-N 2.89Å; Y270-G273 VanDerWaalsContact OH-N 3.14Å; Y270-G273 PolarHBondContact OH-O 2.74Å; G273-F275 PolarHBondContact O-N 2.94Å
274L78.8Confident69.2Low119 Ų11989.2 Ų89.262%0.62343%0.427SS*.  trans-93103.2-178.9-176.668.9000109.5P45P45-L274 HydrophobicContact CB-CB 4.36Å; P45-L274 WeakPolarHBondContact CG-O 3.25Å; P45-L274 PolarHBondContact O-N 2.81Å
275F77.9Confident68Low38 Ų3886.6 Ų86.617%0.16742%0.422CS..  trans-76.9126.4170.5-169.9-95.9000109.6W46 F267 Y270 G273 I277W46-F275 AromaticContact CD2-CD2 3.87Å; W46-F275 HydrophobicContact CD2-CD2 3.87Å; W46-F275 HydrophobicContact CD2-CE2 4.4Å; W46-F275 AromaticContact CE2-CD2 3.83Å; W46-F275 AromaticContact CE2-CE2 3.98Å; W46-F275 HydrophobicContact CE3-CD2 4.11Å; W46-F275 HydrophobicContact CG-CD2 4.29Å; W46-F275 HydrophobicContact CH2-CD2 4.33Å; W46-F275 AromaticContact CH2-CE2 3.96Å; W46-F275 HydrophobicContact CH2-CE2 3.96Å; W46-F275 HydrophobicContact CZ2-CD2 4.11Å; W46-F275 AromaticContact CZ2-CE2 3.79Å; W46-F275 HydrophobicContact CZ2-CE2 3.79Å; W46-F275 HydrophobicContact CZ3-CD2 4.28Å; W46-F275 HydrophobicContact CZ3-CE2 4.3Å; F267-F275 HydrophobicContact CB-CE1 4.13Å; F267-F275 HydrophobicContact CB-CE2 4.33Å; F267-F275 HydrophobicContact CB-CZ 3.8Å; F267-F275 AromaticContact CD2-CD1 3.67Å; F267-F275 HydrophobicContact CD2-CD1 3.67Å; F267-F275 HydrophobicContact CD2-CD2 4.25Å; F267-F275 AromaticContact CD2-CE1 3.66Å; F267-F275 HydrophobicContact CD2-CE1 3.66Å; F267-F275 HydrophobicContact CD2-CE2 4.25Å; F267-F275 AromaticContact CD2-CG 3.98Å; F267-F275 HydrophobicContact CD2-CG 3.98Å; F267-F275 AromaticContact CD2-CZ 3.97Å; F267-F275 HydrophobicContact CD2-CZ 3.97Å; F267-F275 HydrophobicContact CE2-CD1 4.23Å; F267-F275 HydrophobicContact CE2-CG 4.45Å; F267-F275 HydrophobicContact CG-CE1 4.34Å; F267-F275 HydrophobicContact CG-CZ 4.4Å; Y270-F275 HydrophobicContact CD2-CB 3.86Å; Y270-F275 HydrophobicContact CD2-CD2 4.15Å; Y270-F275 HydrophobicContact CD2-CG 4.4Å; Y270-F275 HydrophobicContact CE2-CB 4.02Å; G273-F275 PolarHBondContact O-N 2.94Å; F275-I277 HydrophobicContact CD1-CG1 4.35Å; F275-I277 HydrophobicContact CE1-CG1 3.99Å
276R69.8Low66.9Low193 Ų19387.1 Ų87.173%0.72842%0.421SS*.  trans-122.4115-176.8-164.5-178.8-139.9-1766.5109.9R278R276-R278 PolarHBondContact O-N 3.34Å
277I62.8Low65.5Low55 Ų5587 Ų8728%0.28242%0.419SS..  trans-71.1116.8170.9-58.5171.6000107.8F261 Y264 F275 R279F261-I277 HydrophobicContact CB-CD1 4.09Å; F261-I277 HydrophobicContact CD2-CD1 3.62Å; F261-I277 HydrophobicContact CE2-CD1 4.41Å; F261-I277 HydrophobicContact CG-CD1 4.12Å; Y264-I277 HydrophobicContact CD2-CG2 3.93Å; Y264-I277 HydrophobicContact CE2-CG2 3.49Å; Y264-I277 VanDerWaalsContact CE2-CG2 3.49Å; F275-I277 HydrophobicContact CD1-CG1 4.35Å; F275-I277 HydrophobicContact CE1-CG1 3.99Å; I277-R279 PolarHBondContact O-N 3.43Å
278R54.9Low64.1Low169 Ų16984.8 Ų84.864%0.63841%0.412SS*.  trans-77.5105173.8-67.9-171.2-171.9168.412.2108E36 R276 G280E36-R278 IonicContact OE1-CZ 3.88Å; E36-R278 IonicContact OE1-NH1 2.88Å; E36-R278 PolarHBondContact OE1-NH1 3.3Å; E36-R278 IonicContact OE1-NH2 2.67Å; E36-R278 PolarHBondContact OE1-NH2 3.26Å; E36-R278 IonicContact OE2-CZ 3.17Å; E36-R278 IonicContact OE2-NH1 3.03Å; E36-R278 IonicContact OE2-NH2 3.89Å; E36-R278 PolarHBondContact OE2-NH2 2.92Å; R276-R278 PolarHBondContact O-N 3.34Å; R278-G280 PolarHBondContact O-N 3.32Å
279R46.7Very low63.4Low171 Ų17185.5 Ų85.565%0.64541%0.414SS*.  trans-57.6126.1-178.7-67.2-175.5-178.4-164.3-8.8111.6I277 E287I277-R279 PolarHBondContact O-N 3.43Å; R279-E287 IonicContact CZ-OE1 3.97Å; R279-E287 IonicContact NH2-OE1 2.72Å; R279-E287 PolarHBondContact NH2-OE1 3.46Å; R279-E287 IonicContact NH2-OE2 3.88Å
280G42.8Very low63.1Low32 Ų3285.6 Ų85.633%0.3341%0.414SS..  trans-62.1150.8147.600000109.3R278 D282 E283R278-G280 PolarHBondContact O-N 3.32Å; G280-D282 PolarHBondContact O-N 3.43Å; G280-E283 PolarHBondContact O-N 2.91Å
281K37.2Very low63Low214 Ų21482.1 Ų82.193%0.9340%0.401SS*.THydrogen-bonded Turntrans-60-15.4-171.2-123-179.9-179.3-176.30114.5
282D39.4Very low63.1Low161 Ų16177.4 Ų77.486%0.86138%0.381SS*.THydrogen-bonded Turntrans-125.720.2-174.4-59-53.3000113.9G280G280-D282 PolarHBondContact O-N 3.43Å
283E41.5Very low62.9Low82 Ų8272.7 Ų72.738%0.38336%0.359SS..  trans-96.6118.1176.1-72.1174.4-159.900112.5Y264 G280 G285Y264-E283 PolarHBondContact OH-OE1 3.41Å; Y264-E283 PolarHBondContact OH-OE2 3.09Å; G280-E283 PolarHBondContact O-N 2.91Å; E283-G285 PolarHBondContact O-N 3.37Å
284C44.4Very low62.9Low76 Ų7672.7 Ų72.751%0.51435%0.345SS..  trans-64124.9167.4-62.20000109.8S288 Y289C284-S288 WeakPolarHBondContact CB-OG 3.11Å; C284-Y289 HydrophobicContact CB-CE2 4.37Å
285G56Low63.1Low20 Ų2067.5 Ų67.521%0.20632%0.32CS..  trans-74.5-163.2178.100000113.7E283 E287 S288 Y289E283-G285 PolarHBondContact O-N 3.37Å; G285-E287 VanDerWaalsContact CA-CD 3.46Å; G285-E287 WeakPolarHBondContact CA-OE1 3.22Å; G285-E287 WeakPolarHBondContact CA-OE2 3.3Å; G285-E287 PolarHBondContact N-OE1 2.92Å; G285-E287 PolarHBondContact O-N 3.12Å; G285-S288 PolarHBondContact O-N 3.02Å; G285-Y289 WeakPolarHBondContact O-CD2 3.2Å
286I57.7Low63.1Low64 Ų6469.5 Ų69.533%0.32833%0.329SS..G310 helixtrans-50.8-33.8177.4-69.4167.1000111.9M247 A259 G260 F261 S288 Y289 A290M247-I286 HydrophobicContact CE-CG2 3.74Å; A259-I286 HydrophobicContact CB-CG2 3.3Å; G260-I286 WeakPolarHBondContact O-CA 3.35Å; F261-I286 HydrophobicContact CB-CG1 3.82Å; F261-I286 HydrophobicContact CD1-CG1 4.39Å; F261-I286 HydrophobicContact CG-CG1 4.42Å; I286-S288 PolarHBondContact O-N 3.45Å; I286-S288 VanDerWaalsContact O-N 3.11Å; I286-Y289 CarbonylContact O-C 3.51Å; I286-Y289 PolarHBondContact O-N 3.3Å; I286-A290 PolarHBondContact O-N 3.02Å
287E50.9Low63Low43 Ų4361.7 Ų61.720%0.20130%0.302CS..G310 helixtrans-57.3-25.5-17460.8-85-167.300115.3F240 M247 R279 G285F240-E287 CarbonylContact C-O 3.59Å; M247-E287 HydrophobicContact SD-CB 4.11Å; R279-E287 IonicContact CZ-OE1 3.97Å; R279-E287 IonicContact NH2-OE1 2.72Å; R279-E287 PolarHBondContact NH2-OE1 3.46Å; R279-E287 IonicContact NH2-OE2 3.88Å; G285-E287 VanDerWaalsContact CA-CD 3.46Å; G285-E287 WeakPolarHBondContact CA-OE1 3.22Å; G285-E287 WeakPolarHBondContact CA-OE2 3.3Å; G285-E287 PolarHBondContact N-OE1 2.92Å; G285-E287 PolarHBondContact O-N 3.12Å
288S56.2Low62.5Low22 Ų2265.7 Ų65.715%0.15432%0.317CS..G310 helixtrans-89.3-6.3177.2-62.30000113.3R239 C284 G285 I286R239-S288 PolarHBondContact NE-O 3.12Å; R239-S288 PolarHBondContact NH2-O 3.08Å; C284-S288 WeakPolarHBondContact CB-OG 3.11Å; G285-S288 PolarHBondContact O-N 3.02Å; I286-S288 PolarHBondContact O-N 3.45Å; I286-S288 VanDerWaalsContact O-N 3.11Å
289Y70.5Confident61.5Low24 Ų2465.2 Ų65.29%0.09432%0.317CS..SBendtrans-128.422-171.5-58.3-67.3000112.2Y68 L70 G260 C284 G285 I286Y68-Y289 HydrophobicContact CE1-CD1 4.1Å; Y68-Y289 HydrophobicContact CE1-CG 4.35Å; L70-Y289 HydrophobicContact CD2-CD1 3.63Å; L70-Y289 HydrophobicContact CD2-CD2 4.05Å; L70-Y289 HydrophobicContact CD2-CE1 3.64Å; L70-Y289 HydrophobicContact CD2-CE2 4.06Å; L70-Y289 HydrophobicContact CD2-CG 3.83Å; G260-Y289 PolarHBondContact N-O 3.07Å; G260-Y289 WeakPolarHBondContact O-CB 3.33Å; C284-Y289 HydrophobicContact CB-CE2 4.37Å; G285-Y289 WeakPolarHBondContact O-CD2 3.2Å; I286-Y289 CarbonylContact O-C 3.51Å; I286-Y289 PolarHBondContact O-N 3.3Å
290A83.7Confident60.5Low1 Ų166.1 Ų66.11%0.00833%0.328CS..EExtended strand (participates in β ladder)trans-97.4145.6174.600000111.8R239 F240 M247 I257 V258 I286R239-A290 WeakPolarHBondContact CG-O 3.22Å; F240-A290 HydrophobicContact CB-CB 4.01Å; F240-A290 HydrophobicContact CD2-CB 3.66Å; F240-A290 WeakPolarHBondContact CD2-O 3.4Å; F240-A290 HydrophobicContact CE2-CB 4.44Å; F240-A290 HydrophobicContact CG-CB 4.07Å; F240-A290 PolarHBondContact N-O 3.31Å; M247-A290 HydrophobicContact CE-CB 3.83Å; M247-A290 HydrophobicContact CG-CB 4.4Å; M247-A290 HydrophobicContact SD-CB 4.13Å; I257-A290 HydrophobicContact CD1-CB 4.12Å; V258-A290 CarbonylContact O-C 3.56Å; V258-A290 WeakPolarHBondContact O-CA 3.34Å; V258-A290 WeakPolarHBondContact O-CB 3.34Å; I286-A290 PolarHBondContact O-N 3.02Å
291S88.8Confident59.7Low1 Ų171.6 Ų71.61%0.00735%0.345CS..EExtended strand (participates in β ladder)trans-153.8154.7176.555.50000112F175 Y238 V258F175-S291 WeakPolarHBondContact CE2-O 3.48Å; Y238-S291 VanDerWaalsContact O-CA 3.29Å; Y238-S291 WeakPolarHBondContact O-CA 3.39Å; Y238-S291 VanDerWaalsContact O-CB 3.3Å; Y238-S291 WeakPolarHBondContact O-CB 3.3Å; V258-S291 PolarHBondContact N-O 3.18Å; V258-S291 PolarHBondContact O-N 2.99Å
292A90.7Very high59.1Low0 Ų067.5 Ų67.50%034%0.338CS..EExtended strand (participates in β ladder)trans-158.3-179.4176.300000111.7R137 Y237 Y238 F240 I257R137-A292 VanDerWaalsContact CZ-CB 3.49Å; R137-A292 VanDerWaalsContact NH1-CB 3.31Å; Y237-A292 CarbonylContact C-O 3.56Å; Y238-A292 HydrophobicContact CD2-CB 4.39Å; Y238-A292 HydrophobicContact CE2-CB 3.79Å; Y238-A292 PolarHBondContact N-O 3.39Å; Y238-A292 PolarHBondContact O-N 3.2Å; F240-A292 HydrophobicContact CE2-CB 4.21Å; I257-A292 HydrophobicContact CB-CB 4.24Å; I257-A292 HydrophobicContact CG2-CB 3.84Å
293G86Confident58.3Low0 Ų069.7 Ų69.70%034%0.34CS..EExtended strand (participates in β ladder)trans-146.2169.6167.800000110R137 T236R137-G293 WeakPolarHBondContact CD-O 2.98Å; R137-G293 PolarHBondContact NH1-O 2.91Å; T236-G293 CarbonylContact O-C 3.45Å; T236-G293 WeakPolarHBondContact O-CA 3.19Å
294R84.2Confident57.5Low41 Ų4170.9 Ų70.916%0.15535%0.349CS..EExtended strand (participates in β ladder)trans-103.9136.3173.2-59.4175.8-170.2172.73.1109.4A234 T235 T236 Y238 Y254A234-R294 CarbonylContact C-O 3.59Å; A234-R294 WeakPolarHBondContact CA-O 3.09Å; A234-R294 WeakPolarHBondContact CB-O 3.48Å; T235-R294 PolarHBondContact N-O 2.7Å; T235-R294 WeakPolarHBondContact OG1-CB 3.22Å; T235-R294 PolarHBondContact OG1-O 3.46Å; T236-R294 HydrophobicContact CG2-CB 3.89Å; T236-R294 HydrophobicContact CG2-CG 3.79Å; T236-R294 PolarHBondContact O-N 3.25Å; T236-R294 VanDerWaalsContact O-N 3.11Å; Y238-R294 HydrophobicContact CE1-CG 4.17Å; Y254-R294 VanDerWaalsContact CE2-CZ 3.46Å; Y254-R294 VanDerWaalsContact CE2-NH2 3.29Å; Y254-R294 HydrophobicContact CG-CG 4.42Å; Y254-R294 VanDerWaalsContact OH-CZ 3.28Å; Y254-R294 PolarHBondContact OH-NH1 2.87Å; Y254-R294 PolarHBondContact OH-NH2 2.86Å
295A84Confident56.7Low10 Ų1075.6 Ų75.68%0.08336%0.363CS..EExtended strand (participates in β ladder)trans-72.7147.8179.500000111.8R137 T138 A141 W178R137-A295 HydrophobicContact CB-CB 4.47Å; R137-A295 WeakPolarHBondContact O-CB 3.41Å; T138-A295 VanDerWaalsContact CA-CB 3.46Å; A141-A295 HydrophobicContact CB-CB 3.96Å; W178-A295 HydrophobicContact CH2-CB 3.7Å; W178-A295 HydrophobicContact CZ2-CB 3.84Å
296K77.6Confident55.4Low81 Ų8179.8 Ų79.835%0.35238%0.38SS..  trans-92.6114.4170.8-171.4-178.7-175.4174.90109.6F233 T235F233-K296 HydrophobicContact CB-CB 4.33Å; F233-K296 HydrophobicContact CB-CD 4.08Å; F233-K296 WeakPolarHBondContact O-CB 3.29Å; F233-K296 PolarHBondContact O-N 3.3Å; T235-K296 HydrophobicContact CG2-CB 3.74Å; T235-K296 HydrophobicContact CG2-CG 3.95Å
297V67.2Low54.3Low28 Ų2877.8 Ų77.817%0.1738%0.375CS..  trans-76.1129.8172.3-171.40000109.1A141 Y299A141-V297 HydrophobicContact CB-CG2 3.68Å; A141-V297 WeakPolarHBondContact O-CG2 3.44Å; V297-Y299 HydrophobicContact CB-CD2 4.32Å; V297-Y299 HydrophobicContact CB-CE2 3.88Å; V297-Y299 HydrophobicContact CG1-CD2 4.47Å; V297-Y299 HydrophobicContact CG1-CE2 4.12Å; V297-Y299 PolarHBondContact O-N 3.1Å
298K52.5Low53.6Low140 Ų14079.9 Ų79.961%0.60939%0.387SS*.  trans-73.190.9170.7-74.8-179.7-180172.30108.1K229K229-K298 PolarHBondContact O-NZ 3.43Å
299Y33.9Very low53.2Low158 Ų15879.8 Ų79.862%0.6239%0.385SS*.  trans-76.5127.2158-64.6-77.8000108.1V297 H301V297-Y299 HydrophobicContact CB-CD2 4.32Å; V297-Y299 HydrophobicContact CB-CE2 3.88Å; V297-Y299 HydrophobicContact CG1-CD2 4.47Å; V297-Y299 HydrophobicContact CG1-CE2 4.12Å; V297-Y299 PolarHBondContact O-N 3.1Å; Y299-H301 PolarHBondContact O-N 2.82Å
300E24.9Very low52.2Low190 Ų19080 Ų8089%0.88839%0.387SS*.  trans-65.881169.9-74.5-169.2157.800109.3
301H27Very low50.6Low148 Ų14882.7 Ų82.769%0.68540%0.397SS*.  trans-140.2145.4166.6-73.6-63.8000112Y299Y299-H301 PolarHBondContact O-N 2.82Å
302T24.3Very low49Very low127 Ų12783 Ų8378%0.77940%0.398SS*.  trans-55.1151.4-164-19.20000113.8L304T302-L304 PolarHBondContact O-N 3.2Å
303F23.2Very low46.9Very low208 Ų20889.4 Ų89.491%0.91242%0.423SS*.  trans-47.6105-175.8-68.3-93.1000113.9
304L24.5Very low44.9Very low107 Ų10793.2 Ų93.256%0.5646%0.462SS*.  trans-75125.8155-145.491.8000107.7T302 L306T302-L304 PolarHBondContact O-N 3.2Å; L304-L306 VanDerWaalsContact C-N 3.32Å; L304-L306 HydrophobicContact CD2-CD2 3.93Å; L304-L306 PolarHBondContact O-N 3.08Å
305Q26.3Very low43.2Very low174 Ų17493.3 Ų93.381%0.81347%0.465SS*.  trans-67.391.6168.1-84.1-171.5-1.800109.4
306L29.6Very low41.5Very low109 Ų10995 Ų9557%0.57148%0.476SS*.  trans-78.7129.4174.8-67.1167.6000110.6L304 Y526L304-L306 VanDerWaalsContact C-N 3.32Å; L304-L306 HydrophobicContact CD2-CD2 3.93Å; L304-L306 PolarHBondContact O-N 3.08Å; L306-Y526 HydrophobicContact CB-CD1 4.33Å; L306-Y526 HydrophobicContact CD2-CD1 4.11Å; L306-Y526 HydrophobicContact CD2-CD2 4.36Å; L306-Y526 HydrophobicContact CD2-CG 3.77Å
307G33.8Very low40.3Very low21 Ų2192.3 Ų92.322%0.21647%0.465CS..  trans-143.7133.5160.100000109.2N309 Y526G307-N309 PolarHBondContact O-N 2.82Å; G307-Y526 WeakPolarHBondContact O-CA 3.18Å; G307-Y526 WeakPolarHBondContact O-CD1 3.46Å
308I37.4Very low39.5Very low87 Ų8793 Ų9345%0.44647%0.474SS..  trans-61.8112.5176.6-62.8168.3000107.4D310 R313 Y526I308-D310 PolarHBondContact O-N 2.69Å; I308-R313 HydrophobicContact CG2-CB 4.19Å; I308-Y526 HydrophobicContact CB-CE1 4.29Å; I308-Y526 HydrophobicContact CG1-CD1 4.16Å; I308-Y526 HydrophobicContact CG1-CE1 3.44Å; I308-Y526 VanDerWaalsContact CG1-CE1 3.44Å
309N46.5Very low39.5Very low21 Ų2189.7 Ų89.711%0.11246%0.463CS..  trans-61.5130.4172.8-177-61000109.4G307 R311 F312 R313 Y525G307-N309 PolarHBondContact O-N 2.82Å; N309-R311 PolarHBondContact O-N 3.25Å; N309-R311 VanDerWaalsContact O-N 3.08Å; N309-R311 WeakPolarHBondContact OD1-CB 3.44Å; N309-R311 PolarHBondContact OD1-N 3.49Å; N309-F312 HydrophobicContact CB-CD2 4.02Å; N309-F312 HydrophobicContact CB-CE2 4.4Å; N309-F312 PolarHBondContact O-N 3.29Å; N309-R313 PolarHBondContact O-N 2.93Å; N309-Y525 WeakPolarHBondContact CB-O 3.07Å; N309-Y525 PolarHBondContact N-O 2.65Å
310D49.5Very low40.7Very low27 Ų2783.4 Ų83.414%0.14444%0.439CS..THydrogen-bonded Turntrans-60.5-20.5-171.3-86.537.8000114.6I308 R313 F613 K617I308-D310 PolarHBondContact O-N 2.69Å; D310-R313 IonicContact OD1-CZ 3.57Å; D310-R313 IonicContact OD1-NH1 3.41Å; D310-R313 PolarHBondContact OD1-NH1 2.88Å; D310-R313 IonicContact OD1-NH2 2.81Å; D310-R313 PolarHBondContact OD1-NH2 2.81Å; D310-R313 IonicContact OD2-CZ 2.7Å; D310-R313 IonicContact OD2-NH1 3.9Å; D310-R313 PolarHBondContact OD2-NH1 3.43Å; D310-R313 IonicContact OD2-NH2 3.53Å; D310-F613 HydrophobicContact CB-CE1 4.09Å; D310-K617 WeakPolarHBondContact OD2-CD 3.32Å; D310-K617 VanDerWaalsContact OD2-CE 3.23Å; D310-K617 WeakPolarHBondContact OD2-CE 3.42Å; D310-K617 IonicContact OD2-NZ 3.79Å; D310-K617 PolarHBondContact OD2-NZ 3.24Å
311R51.9Low42.4Very low58 Ų5877.4 Ų77.422%0.21941%0.411CS..THydrogen-bonded Turntrans-66.2-37.4173.1-172.4176.3-175.9122.32.8112N309 M315 D371 S373 W565N309-R311 PolarHBondContact O-N 3.25Å; N309-R311 VanDerWaalsContact O-N 3.08Å; N309-R311 WeakPolarHBondContact OD1-CB 3.44Å; N309-R311 PolarHBondContact OD1-N 3.49Å; R311-M315 WeakPolarHBondContact O-CE 3.29Å; R311-D371 IonicContact CZ-OD1 2.89Å; R311-D371 VanDerWaalsContact CZ-OD1 3.26Å; R311-D371 IonicContact CZ-OD2 3.45Å; R311-D371 IonicContact NH1-OD1 2.79Å; R311-D371 PolarHBondContact NH1-OD1 3.36Å; R311-D371 IonicContact NH1-OD2 3.9Å; R311-D371 PolarHBondContact NH1-OD2 2.96Å; R311-D371 IonicContact NH2-OD1 3.32Å; R311-D371 PolarHBondContact NH2-OD1 3.26Å; R311-S373 PolarHBondContact NH2-O 2.86Å; R311-S373 VanDerWaalsContact NH2-O 3.07Å; R311-W565 VanDerWaalsContact NH1-CA 3.32Å; R311-W565 PolarHBondContact NH1-O 2.79Å
312F53.4Low43.8Very low7 Ų772.4 Ų72.43%0.03140%0.395CS..THydrogen-bonded Turntrans-90.5-5.8-179.3-53.4-73.7000113.6N309 G314 M315 F323 Y525 W565 W569N309-F312 HydrophobicContact CB-CD2 4.02Å; N309-F312 HydrophobicContact CB-CE2 4.4Å; N309-F312 PolarHBondContact O-N 3.29Å; F312-G314 PolarHBondContact O-N 2.93Å; F312-M315 HydrophobicContact CB-CE 4.26Å; F312-M315 HydrophobicContact CD1-CE 3.41Å; F312-M315 VanDerWaalsContact CD1-CE 3.41Å; F312-M315 HydrophobicContact CE1-CE 4.08Å; F312-M315 HydrophobicContact CG-CE 4.2Å; F312-M315 PolarHBondContact O-N 3.47Å; F312-F323 HydrophobicContact CE1-CD1 4.42Å; F312-F323 HydrophobicContact CE1-CE1 4.11Å; F312-Y525 AromaticContact CD1-CD1 3.88Å; F312-Y525 HydrophobicContact CD1-CD1 3.88Å; F312-Y525 HydrophobicContact CD1-CE1 4.12Å; F312-Y525 HydrophobicContact CD1-CG 4.3Å; F312-Y525 AromaticContact CD2-CD1 3.88Å; F312-Y525 HydrophobicContact CD2-CD1 3.88Å; F312-Y525 AromaticContact CD2-CG 3.96Å; F312-Y525 HydrophobicContact CD2-CG 3.96Å; F312-Y525 AromaticContact CE1-CD1 3.81Å; F312-Y525 HydrophobicContact CE1-CD1 3.81Å; F312-Y525 AromaticContact CE1-CE1 3.96Å; F312-Y525 HydrophobicContact CE1-CE1 3.96Å; F312-Y525 AromaticContact CE2-CD1 3.79Å; F312-Y525 HydrophobicContact CE2-CD1 3.79Å; F312-Y525 HydrophobicContact CE2-CG 4.3Å; F312-Y525 AromaticContact CG-CD1 3.96Å; F312-Y525 HydrophobicContact CG-CD1 3.96Å; F312-Y525 AromaticContact CG-CG 3.99Å; F312-Y525 HydrophobicContact CG-CG 3.99Å; F312-Y525 AromaticContact CZ-CD1 3.78Å; F312-Y525 HydrophobicContact CZ-CD1 3.78Å; F312-Y525 HydrophobicContact CZ-CE1 4.27Å; F312-W565 HydrophobicContact CE1-CZ3 4.46Å; F312-W565 AromaticContact CE2-CE3 3.97Å; F312-W565 HydrophobicContact CE2-CE3 3.97Å; F312-W565 AromaticContact CE2-CZ3 3.87Å; F312-W565 HydrophobicContact CE2-CZ3 3.87Å; F312-W565 AromaticContact CZ-CD2 3.93Å; F312-W565 HydrophobicContact CZ-CD2 3.93Å; F312-W565 AromaticContact CZ-CE3 3.44Å; F312-W565 HydrophobicContact CZ-CE3 3.44Å; F312-W565 VanDerWaalsContact CZ-CE3 3.44Å; F312-W565 AromaticContact CZ-CH2 3.83Å; F312-W565 HydrophobicContact CZ-CH2 3.83Å; F312-W565 HydrophobicContact CZ-CZ2 4.29Å; F312-W565 AromaticContact CZ-CZ3 3.39Å; F312-W565 HydrophobicContact CZ-CZ3 3.39Å; F312-W569 AromaticContact CE2-CD1 3.79Å; F312-W569 AromaticContact CE2-NE1 3.89Å
313R47.2Very low45.4Very low135 Ų13566.8 Ų66.851%0.50936%0.36SS..THydrogen-bonded Turntrans-65.7111.1-177.3-173179.7-72.7140.810.5110.2I308 N309 D310I308-R313 HydrophobicContact CG2-CB 4.19Å; N309-R313 PolarHBondContact O-N 2.93Å; D310-R313 IonicContact OD1-CZ 3.57Å; D310-R313 IonicContact OD1-NH1 3.41Å; D310-R313 PolarHBondContact OD1-NH1 2.88Å; D310-R313 IonicContact OD1-NH2 2.81Å; D310-R313 PolarHBondContact OD1-NH2 2.81Å; D310-R313 IonicContact OD2-CZ 2.7Å; D310-R313 IonicContact OD2-NH1 3.9Å; D310-R313 PolarHBondContact OD2-NH1 3.43Å; D310-R313 IonicContact OD2-NH2 3.53Å
314G44.2Very low47.3Very low80 Ų8057 Ų5783%0.82532%0.316SS*.THydrogen-bonded Turntrans92.30.4176.600000115.3F312F312-G314 PolarHBondContact O-N 2.93Å
315M49.3Very low48.9Very low44 Ų4452.9 Ų52.922%0.21730%0.3CS..  trans-72.7137.5167.3-82.8-166.1-76.200109.8R311 F312 D319 M320 F323R311-M315 WeakPolarHBondContact O-CE 3.29Å; F312-M315 HydrophobicContact CB-CE 4.26Å; F312-M315 HydrophobicContact CD1-CE 3.41Å; F312-M315 VanDerWaalsContact CD1-CE 3.41Å; F312-M315 HydrophobicContact CE1-CE 4.08Å; F312-M315 HydrophobicContact CG-CE 4.2Å; F312-M315 PolarHBondContact O-N 3.47Å; M315-D319 HydrophobicContact CB-CB 4.03Å; M315-D319 HydrophobicContact CG-CB 4.02Å; M315-D319 HydrophobicContact SD-CB 4.26Å; M315-M320 HydrophobicContact CB-CE 4Å; M315-M320 HydrophobicContact CB-CG 3.8Å; M315-M320 HydrophobicContact CE-CG 4.44Å; M315-M320 WeakPolarHBondContact O-CE 3.25Å; M315-M320 HydrophobicContact SD-CG 4.45Å; M315-F323 HydrophobicContact SD-CB 4.43Å
316S47.2Very low50.1Low45 Ų4546 Ų4632%0.31527%0.27SS..  trans-71163165.2690000110.2A318 D319 M320S316-A318 PolarHBondContact O-N 3.12Å; S316-D319 WeakPolarHBondContact CB-OD2 3.49Å; S316-D319 PolarHBondContact N-OD2 3.4Å; S316-D319 VanDerWaalsContact N-OD2 3.08Å; S316-D319 PolarHBondContact O-N 3.31Å; S316-D319 VanDerWaalsContact O-N 3.17Å; S316-D319 PolarHBondContact OG-N 3.35Å; S316-D319 PolarHBondContact OG-OD2 3.32Å; S316-M320 VanDerWaalsContact O-CG 3.3Å; S316-M320 WeakPolarHBondContact O-CG 3.42Å; S316-M320 PolarHBondContact O-N 3.07Å
317L51.9Low50.9Low24 Ų2443.6 Ų43.613%0.12626%0.262CS..Hα-helixtrans-57.6-36173.7-176.468.5000111.7P82 E86 Y87 M320 K321 I538 A540P82-L317 HydrophobicContact CB-CB 4.39Å; P82-L317 HydrophobicContact CB-CD2 3.67Å; P82-L317 HydrophobicContact CG-CD2 4.27Å; E86-L317 HydrophobicContact CB-CD2 4.05Å; Y87-L317 HydrophobicContact CD1-CD2 3.73Å; Y87-L317 HydrophobicContact CE1-CD2 3.26Å; L317-M320 WeakPolarHBondContact O-CB 3.31Å; L317-M320 PolarHBondContact O-N 3.31Å; L317-K321 HydrophobicContact CG-CD 4.34Å; L317-K321 WeakPolarHBondContact O-CG 3.46Å; L317-K321 PolarHBondContact O-N 2.96Å; L317-I538 HydrophobicContact CD1-CD1 3.88Å; L317-I538 HydrophobicContact CD2-CD1 4.24Å; L317-A540 HydrophobicContact CD1-CB 4.39Å
318A51.5Low51.4Low43 Ų4345.7 Ų45.736%0.35527%0.265SS..Hα-helixtrans-64.9-44.3176.100000112S316 M320 K321 A322S316-A318 PolarHBondContact O-N 3.12Å; A318-M320 VanDerWaalsContact C-N 3.28Å; A318-M320 PolarHBondContact O-N 3.1Å; A318-K321 PolarHBondContact O-N 2.87Å; A318-A322 WeakPolarHBondContact O-CB 3.47Å; A318-A322 PolarHBondContact O-N 3.28Å
319D52.8Low51.6Low71 Ų7148.9 Ų48.938%0.3828%0.278SS..Hα-helixtrans-61.7-39.4173.9-61.6-45.7000111M315 S316 A322 F323M315-D319 HydrophobicContact CB-CB 4.03Å; M315-D319 HydrophobicContact CG-CB 4.02Å; M315-D319 HydrophobicContact SD-CB 4.26Å; S316-D319 WeakPolarHBondContact CB-OD2 3.49Å; S316-D319 PolarHBondContact N-OD2 3.4Å; S316-D319 VanDerWaalsContact N-OD2 3.08Å; S316-D319 PolarHBondContact O-N 3.31Å; S316-D319 VanDerWaalsContact O-N 3.17Å; S316-D319 PolarHBondContact OG-N 3.35Å; S316-D319 PolarHBondContact OG-OD2 3.32Å; D319-A322 PolarHBondContact O-N 3.22Å; D319-F323 WeakPolarHBondContact O-CB 3.39Å; D319-F323 PolarHBondContact O-N 3.36Å
320M58.8Low51.4Low25 Ų2551.9 Ų51.912%0.12330%0.297CS..Hα-helixtrans-64.3-43.1177.2-67.2-179.5-152.300111.8M315 S316 L317 A318 F323 L324 Y525M315-M320 HydrophobicContact CB-CE 4Å; M315-M320 HydrophobicContact CB-CG 3.8Å; M315-M320 HydrophobicContact CE-CG 4.44Å; M315-M320 WeakPolarHBondContact O-CE 3.25Å; M315-M320 HydrophobicContact SD-CG 4.45Å; S316-M320 VanDerWaalsContact O-CG 3.3Å; S316-M320 WeakPolarHBondContact O-CG 3.42Å; S316-M320 PolarHBondContact O-N 3.07Å; L317-M320 WeakPolarHBondContact O-CB 3.31Å; L317-M320 PolarHBondContact O-N 3.31Å; A318-M320 VanDerWaalsContact C-N 3.28Å; A318-M320 PolarHBondContact O-N 3.1Å; M320-F323 CarbonylContact O-C 3.02Å; M320-F323 WeakPolarHBondContact O-CB 3.4Å; M320-F323 PolarHBondContact O-N 2.7Å; M320-L324 VanDerWaalsContact O-CG 3.32Å; M320-L324 WeakPolarHBondContact O-CG 3.38Å; M320-L324 PolarHBondContact O-N 3.45Å; M320-Y525 HydrophobicContact CE-CE2 4.48Å; M320-Y525 HydrophobicContact SD-CD2 4.05Å; M320-Y525 HydrophobicContact SD-CE2 3.26Å; M320-Y525 WeakPolarHBondContact SD-CE2 3.16Å
321K59.9Low50.8Low65 Ų6555.9 Ų55.928%0.28331%0.314SS..Hα-helixtrans-61-47.7174.9-80.3159162.1-103.90112.6E86 L317 A318 F323 L324 G325 A540E86-K321 VanDerWaalsContact C-NZ 3.28Å; E86-K321 HydrophobicContact CB-CD 4.31Å; E86-K321 HydrophobicContact CG-CD 4.47Å; E86-K321 WeakPolarHBondContact O-CE 3.46Å; E86-K321 PolarHBondContact O-NZ 2.81Å; L317-K321 HydrophobicContact CG-CD 4.34Å; L317-K321 WeakPolarHBondContact O-CG 3.46Å; L317-K321 PolarHBondContact O-N 2.96Å; A318-K321 PolarHBondContact O-N 2.87Å; K321-F323 PolarHBondContact O-N 2.82Å; K321-L324 PolarHBondContact O-N 3.09Å; K321-G325 PolarHBondContact O-N 3.26Å; K321-A540 WeakPolarHBondContact CG-O 3.45Å
322A56.3Low50Low43 Ų4359.1 Ų59.136%0.35533%0.331SS..Hα-helixtrans-59-36.117600000110.9A318 D319 G376 P397A318-A322 WeakPolarHBondContact O-CB 3.47Å; A318-A322 PolarHBondContact O-N 3.28Å; D319-A322 PolarHBondContact O-N 3.22Å; A322-G376 VanDerWaalsContact O-CA 3.24Å; A322-G376 WeakPolarHBondContact O-CA 3.14Å; A322-P397 HydrophobicContact CB-CB 4.13Å; A322-P397 HydrophobicContact CB-CG 4.38Å
323F58.8Low49.1Very low9 Ų965.7 Ų65.74%0.03937%0.367CS..Hα-helixtrans-69.5-41.4175.8176.6-87.5000113.3F312 M315 D319 M320 K321 G325 Q372 S373 W565F312-F323 HydrophobicContact CE1-CD1 4.42Å; F312-F323 HydrophobicContact CE1-CE1 4.11Å; M315-F323 HydrophobicContact SD-CB 4.43Å; D319-F323 WeakPolarHBondContact O-CB 3.39Å; D319-F323 PolarHBondContact O-N 3.36Å; M320-F323 CarbonylContact O-C 3.02Å; M320-F323 WeakPolarHBondContact O-CB 3.4Å; M320-F323 PolarHBondContact O-N 2.7Å; K321-F323 PolarHBondContact O-N 2.82Å; F323-G325 VanDerWaalsContact C-N 3.26Å; F323-G325 PolarHBondContact O-N 3.36Å; F323-Q372 HydrophobicContact CE2-CG 3.91Å; F323-Q372 HydrophobicContact CZ-CG 3.75Å; F323-Q372 PolarHBondContact O-NE2 2.01Å; F323-S373 WeakPolarHBondContact CE2-O 3.45Å; F323-W565 AromaticContact CE1-CD1 3.72Å; F323-W565 HydrophobicContact CE1-CD2 4.38Å; F323-W565 AromaticContact CE1-CE2 3.85Å; F323-W565 HydrophobicContact CE1-CG 4.33Å; F323-W565 HydrophobicContact CE1-CZ2 4.43Å; F323-W565 AromaticContact CE1-NE1 3.42Å; F323-W565 AromaticContact CZ-CD1 3.68Å; F323-W565 HydrophobicContact CZ-CG 4.27Å; F323-W565 AromaticContact CZ-NE1 3.89Å
324L63.5Low48.5Very low1 Ų161.3 Ų61.31%0.00536%0.357CS..Hα-helixtrans-68.5-20.8-176.6-69.4177.8000114.5M320 K321 V326 C378 V520 A540 Y542 H543 W565M320-L324 VanDerWaalsContact O-CG 3.32Å; M320-L324 WeakPolarHBondContact O-CG 3.38Å; M320-L324 PolarHBondContact O-N 3.45Å; K321-L324 PolarHBondContact O-N 3.09Å; L324-V326 VanDerWaalsContact C-N 3.27Å; L324-V326 PolarHBondContact O-N 3.36Å; L324-V326 VanDerWaalsContact O-N 3.08Å; L324-C378 PolarHBondContact O-SG 2.65Å; L324-V520 HydrophobicContact CD1-CB 3.84Å; L324-V520 HydrophobicContact CD1-CG1 3.91Å; L324-V520 HydrophobicContact CD1-CG2 4.44Å; L324-V520 HydrophobicContact CD2-CB 4.29Å; L324-V520 HydrophobicContact CD2-CG1 4.1Å; L324-V520 HydrophobicContact CD2-CG2 4.14Å; L324-A540 HydrophobicContact CD1-CB 3.83Å; L324-A540 WeakPolarHBondContact CD1-O 3.36Å; L324-Y542 VanDerWaalsContact O-O 3.12Å; L324-H543 HydrophobicContact CD2-CB 4.16Å; L324-H543 PolarHBondContact O-ND1 3.23Å; L324-W565 HydrophobicContact CD2-CH2 4.41Å; L324-W565 HydrophobicContact CD2-CZ2 3.7Å
325G56.9Low47.8Very low21 Ų2165.3 Ų65.322%0.21636%0.359CS..  trans71.41.1157.700000118.4K321 F323 G376 C378K321-G325 PolarHBondContact O-N 3.26Å; F323-G325 VanDerWaalsContact C-N 3.26Å; F323-G325 PolarHBondContact O-N 3.36Å; G325-G376 WeakPolarHBondContact CA-O 2.98Å; G325-C378 VanDerWaalsContact CA-SG 3.58Å
326V51.2Low47.1Very low31 Ų3168 Ų6819%0.18837%0.37CS..BIsolated β-bridgetrans-118120.9174.6-176.70000109.7L324 C378 Y542L324-V326 VanDerWaalsContact C-N 3.27Å; L324-V326 PolarHBondContact O-N 3.36Å; L324-V326 VanDerWaalsContact O-N 3.08Å; V326-C378 HydrophobicContact CG2-CB 4.06Å; V326-Y542 WeakPolarHBondContact CB-O 3.01Å
327S46.8Very low46.5Very low57 Ų5772.1 Ų72.140%0.39939%0.394SS..  trans-102.9144.217493.30000110.7T330S327-T330 PolarHBondContact OG-OG1 3.11Å
328K44.5Very low46.2Very low65 Ų6575 Ų7528%0.28341%0.408SS..SBendtrans-69.7-36.8179.7-167.1-177.8174.5-1710112.5T330 F331 E332 Y542K328-T330 PolarHBondContact O-N 2.85Å; K328-F331 PolarHBondContact O-N 2.94Å; K328-E332 WeakPolarHBondContact CE-OE1 3.23Å; K328-E332 IonicContact NZ-OE1 2.69Å; K328-Y542 HydrophobicContact CB-CD2 4.41Å; K328-Y542 HydrophobicContact CB-CE2 3.8Å; K328-Y542 HydrophobicContact CD-CE2 4.38Å; K328-Y542 HydrophobicContact CG-CE2 4.25Å
329E42.2Very low46.2Very low155 Ų15578.5 Ų78.572%0.72442%0.417SS*.Hα-helixtrans-61.9-29.7-174.7-68.8166.7-177.900112.4F331E329-F331 VanDerWaalsContact C-N 3.25Å; E329-F331 PolarHBondContact O-N 3.4Å
330T41Very low46.4Very low83 Ų8378.5 Ų78.551%0.50942%0.42SS..Hα-helixtrans-72.4-14.9177.5-30.80000113.7S327 K328 S334S327-T330 PolarHBondContact OG-OG1 3.11Å; K328-T330 PolarHBondContact O-N 2.85Å; T330-S334 VanDerWaalsContact O-CB 3.32Å; T330-S334 WeakPolarHBondContact O-CB 3.4Å; T330-S334 PolarHBondContact O-OG 3.47Å
331F36.6Very low46.7Very low111 Ų11179 Ų7949%0.48742%0.422SS..Hα-helixtrans-97.9-36.5-174.8-103.8-86.6000113.9K328 E329 S334K328-F331 PolarHBondContact O-N 2.94Å; E329-F331 VanDerWaalsContact C-N 3.25Å; E329-F331 PolarHBondContact O-N 3.4Å; F331-S334 PolarHBondContact O-OG 2.74Å
332E36.9Very low46.8Very low126 Ų12679.8 Ų79.859%0.58943%0.43SS*.Hα-helixtrans-83.4-33.3-176-71.5179.1-179.100112.9K328 S334K328-E332 WeakPolarHBondContact CE-OE1 3.23Å; K328-E332 IonicContact NZ-OE1 2.69Å; E332-S334 VanDerWaalsContact C-N 3.31Å; E332-S334 PolarHBondContact O-N 2.97Å
333D33Very low46.9Very low145 Ų14582.1 Ų82.178%0.77544%0.437SS*.SBendtrans-86.4-3.3-179.5-71-24.8000113.7N335D333-N335 PolarHBondContact O-N 3.47Å
334S34.8Very low46.6Very low43 Ų4388.1 Ų88.130%0.30147%0.468SS..  trans-88.1104.1-175.285.80000108.7T330 F331 E332 F336T330-S334 VanDerWaalsContact O-CB 3.32Å; T330-S334 WeakPolarHBondContact O-CB 3.4Å; T330-S334 PolarHBondContact O-OG 3.47Å; F331-S334 PolarHBondContact O-OG 2.74Å; E332-S334 VanDerWaalsContact C-N 3.31Å; E332-S334 PolarHBondContact O-N 2.97Å; S334-F336 VanDerWaalsContact CB-CD2 3.41Å; S334-F336 PolarHBondContact O-N 2.98Å
335N30.4Very low46.2Very low164 Ų16491.1 Ų91.188%0.87749%0.489SS*.  trans-69.236.1179.2-118.7-1.3000112.9D333D333-N335 PolarHBondContact O-N 3.47Å
336F34.1Very low46.2Very low101 Ų10195.2 Ų95.244%0.44352%0.521SS..  trans-85.8112.8-177.2-73.4-93.3000110.8S334 I338S334-F336 VanDerWaalsContact CB-CD2 3.41Å; S334-F336 PolarHBondContact O-N 2.98Å; F336-I338 PolarHBondContact O-N 3.33Å
337T34.9Very low47Very low132 Ų13296.2 Ų96.281%0.8153%0.527SS*.  trans-83.681167.650.40000110.1
338I46.1Very low48.6Very low83 Ų8399 Ų9943%0.42655%0.547SS..PPolyproline II helixtrans-88.2131.4164.6-62.5174.3000107.8F336 T340 R496F336-I338 PolarHBondContact O-N 3.33Å; I338-T340 PolarHBondContact O-N 3.41Å; I338-R496 HydrophobicContact CG2-CB 4.24Å
339E51.6Low50.6Low118 Ų11898.3 Ų98.355%0.55155%0.546SS*.PPolyproline II helixtrans-56.9126.2176.1-169.9178.6131.400110.4R493 R496E339-R493 IonicContact OE1-CZ 3.87Å; E339-R493 IonicContact OE1-NH2 2.81Å; E339-R493 PolarHBondContact OE1-NH2 2.93Å; E339-R493 IonicContact OE2-CZ 2.74Å; E339-R493 IonicContact OE2-NH2 3.62Å; E339-R493 PolarHBondContact OE2-NH2 3.16Å; E339-R496 PolarHBondContact O-N 2.69Å
340T56.9Low52.8Low70 Ų7093.2 Ų93.243%0.42953%0.526SS..EExtended strand (participates in β ladder)trans-93.9117.3173.7-60.30000108.1I338 D342 R496 A498I338-T340 PolarHBondContact O-N 3.41Å; T340-D342 PolarHBondContact O-N 3.28Å; T340-R496 CarbonylContact C-O 3.15Å; T340-R496 WeakPolarHBondContact CA-O 3.42Å; T340-A498 HydrophobicContact CG2-CB 3.98Å
341I65.1Low55.1Low35 Ų3596.6 Ų96.618%0.17954%0.536CS..EExtended strand (participates in β ladder)trans-82.9114.8173.5-56.2-178000107.6D343 Y495 R496 A498I341-D343 HydrophobicContact CG2-CB 4.17Å; I341-Y495 HydrophobicContact CD1-CD1 4.15Å; I341-Y495 HydrophobicContact CD1-CD2 3.43Å; I341-Y495 VanDerWaalsContact CD1-CD2 3.43Å; I341-Y495 HydrophobicContact CD1-CE1 4.48Å; I341-Y495 HydrophobicContact CD1-CE2 3.82Å; I341-Y495 HydrophobicContact CD1-CG 3.62Å; I341-Y495 HydrophobicContact CG1-CD2 4.01Å; I341-Y495 HydrophobicContact CG1-CG 4.27Å; I341-R496 PolarHBondContact N-O 3.39Å; I341-A498 PolarHBondContact O-N 2.04Å; I341-A498 VanDerWaalsContact O-N 3.14Å
342D60.6Low57.6Low82 Ų8297.1 Ų97.144%0.43954%0.54SS..  trans-12125.8175.4-160.220.9000111.2T340 L344 A498T340-D342 PolarHBondContact O-N 3.28Å; D342-L344 WeakPolarHBondContact O-CG 3.25Å; D342-L344 PolarHBondContact O-N 3.5Å; D342-A498 HydrophobicContact CB-CB 3.89Å; D342-A498 VanDerWaalsContact OD1-CB 3.23Å; D342-A498 WeakPolarHBondContact OD1-CB 3.16Å
343D58.1Low60.1Low93 Ų9391.7 Ų91.750%0.49752%0.515SS..  trans-62.8101.3-170.4176.223.8000113I341 S345 K506I341-D343 HydrophobicContact CG2-CB 4.17Å; D343-S345 VanDerWaalsContact C-N 3.26Å; D343-S345 VanDerWaalsContact CG-OG 3.25Å; D343-S345 PolarHBondContact O-N 3.35Å; D343-S345 WeakPolarHBondContact OD1-CB 3.38Å; D343-S345 PolarHBondContact OD1-N 2.92Å; D343-S345 PolarHBondContact OD1-OG 3.43Å; D343-S345 PolarHBondContact OD2-OG 3.16Å; D343-K506 PolarHBondContact O-NZ 3.06Å; D343-K506 IonicContact OD1-NZ 3.5Å; D343-K506 IonicContact OD2-NZ 3.46Å; D343-K506 PolarHBondContact OD2-NZ 2.99Å
344L52.4Low62.8Low134 Ų13486.2 Ų86.270%0.70249%0.485SS*.  trans-74.77.9-179.5-67.5169.8000115D342 A346D342-L344 WeakPolarHBondContact O-CG 3.25Å; D342-L344 PolarHBondContact O-N 3.5Å; L344-A346 PolarHBondContact O-N 3.33Å
345S57Low64.9Low64 Ų6484.1 Ų84.145%0.44847%0.471SS..  trans-63.4129.2176.454.20000112D343 V347 K506D343-S345 VanDerWaalsContact C-N 3.26Å; D343-S345 VanDerWaalsContact CG-OG 3.25Å; D343-S345 PolarHBondContact O-N 3.35Å; D343-S345 WeakPolarHBondContact OD1-CB 3.38Å; D343-S345 PolarHBondContact OD1-N 2.92Å; D343-S345 PolarHBondContact OD1-OG 3.43Å; D343-S345 PolarHBondContact OD2-OG 3.16Å; S345-V347 PolarHBondContact O-N 3.18Å; S345-K506 PolarHBondContact O-NZ 3.25Å; S345-K506 PolarHBondContact OG-NZ 2.9Å
346A56.6Low67.2Low108 Ų10880.6 Ų80.689%0.89345%0.445SS*.  trans-65.498.9-168.800000113.2L344L344-A346 PolarHBondContact O-N 3.33Å
347V68.3Low69.4Low51 Ų5180.8 Ų80.831%0.30946%0.455SS..  trans-97.1126.4162.6178.70000107.3S345 L349 K506 Y509S345-V347 PolarHBondContact O-N 3.18Å; V347-L349 HydrophobicContact CG1-CD2 4.22Å; V347-L349 PolarHBondContact O-N 3.44Å; V347-L349 VanDerWaalsContact O-N 3.16Å; V347-K506 HydrophobicContact CG2-CD 4.21Å; V347-K506 HydrophobicContact CG2-CG 4.45Å; V347-Y509 HydrophobicContact CG1-CD1 4.36Å; V347-Y509 HydrophobicContact CG1-CE1 4.47Å
348S79.4Confident71.6Confident116 Ų11679.3 Ų79.381%0.81144%0.439SS*.  trans-71.6105.3172580000109.4
349L86.1Confident73.2Confident50 Ų5078.1 Ų78.126%0.26243%0.429SS..  trans-90.9141.4-179.8-65.2164.6000110.5V347 M505 Y509 W550V347-L349 HydrophobicContact CG1-CD2 4.22Å; V347-L349 PolarHBondContact O-N 3.44Å; V347-L349 VanDerWaalsContact O-N 3.16Å; L349-M505 HydrophobicContact CB-CE 4.34Å; L349-M505 HydrophobicContact CD1-CB 3.61Å; L349-M505 HydrophobicContact CD1-CE 4.35Å; L349-M505 HydrophobicContact CD1-SD 4.28Å; L349-Y509 HydrophobicContact CD2-CD1 4.01Å; L349-Y509 HydrophobicContact CD2-CG 3.86Å; L349-W550 HydrophobicContact CB-CZ2 4.47Å; L349-W550 HydrophobicContact CD2-CH2 4.42Å
350P89.4Confident74.3Confident49 Ų4976.6 Ų76.632%0.31843%0.432SS..  trans-69.6155.6175.130.9-36.6000111.9E352 F353 Y509 W550P350-E352 VanDerWaalsContact C-N 3.28Å; P350-E352 WeakPolarHBondContact CB-O 3.38Å; P350-E352 WeakPolarHBondContact CG-O 3.37Å; P350-E352 PolarHBondContact O-N 3.42Å; P350-F353 HydrophobicContact CG-CB 4.3Å; P350-Y509 HydrophobicContact CG-CD2 4.49Å; P350-Y509 HydrophobicContact CG-CE2 4.15Å; P350-W550 HydrophobicContact CG-CZ2 4.03Å; P350-W550 PolarHBondContact O-NE1 2.71Å
351E87.9Confident74.8Confident154 Ų15480.3 Ų80.372%0.7244%0.444SS*.SBendtrans-65.5-31.2175.5-72.5-167.2150.300112.7W550E351-W550 VanDerWaalsContact O-CD1 3.25Å; E351-W550 PolarHBondContact O-NE1 2.9Å
352E89.4Confident74.9Confident121 Ų12181.1 Ų81.157%0.56545%0.452SS*.SBendtrans-127.5141.5175.1-58-170.2158.300110.9P350 W550P350-E352 VanDerWaalsContact C-N 3.28Å; P350-E352 WeakPolarHBondContact CB-O 3.38Å; P350-E352 WeakPolarHBondContact CG-O 3.37Å; P350-E352 PolarHBondContact O-N 3.42Å; E352-W550 WeakPolarHBondContact CA-O 3.26Å
353F90.8Very high74.9Confident13 Ų1378.4 Ų78.46%0.05744%0.441CS..EExtended strand (participates in β ladder)trans-148.1135.3178.2179.9-102.9000111.3P350 A355 Q358 W359 L508 Y509 G549 W550P350-F353 HydrophobicContact CG-CB 4.3Å; F353-A355 HydrophobicContact CE1-CB 4.23Å; F353-Q358 HydrophobicContact CE2-CB 3.65Å; F353-Q358 HydrophobicContact CE2-CG 3.77Å; F353-Q358 HydrophobicContact CZ-CB 3.89Å; F353-Q358 HydrophobicContact CZ-CG 4.07Å; F353-W359 HydrophobicContact CE1-CH2 4.39Å; F353-W359 HydrophobicContact CE1-CZ3 4.11Å; F353-W359 AromaticContact CZ-CH2 3.69Å; F353-W359 HydrophobicContact CZ-CH2 3.69Å; F353-W359 AromaticContact CZ-CZ3 3.6Å; F353-W359 HydrophobicContact CZ-CZ3 3.6Å; F353-L508 HydrophobicContact CD1-CD2 4.23Å; F353-L508 HydrophobicContact CD1-CG 4.06Å; F353-L508 HydrophobicContact CE1-CD1 4.19Å; F353-L508 HydrophobicContact CE1-CD2 4.43Å; F353-L508 HydrophobicContact CE1-CG 3.81Å; F353-Y509 AromaticContact CD2-CD2 3.66Å; F353-Y509 HydrophobicContact CD2-CD2 3.66Å; F353-Y509 HydrophobicContact CD2-CE2 4.01Å; F353-Y509 AromaticContact CE2-CD2 3.52Å; F353-Y509 HydrophobicContact CE2-CD2 3.52Å; F353-Y509 AromaticContact CE2-CE2 3.92Å; F353-Y509 HydrophobicContact CE2-CE2 3.92Å; F353-Y509 HydrophobicContact CG-CD2 4.39Å; F353-Y509 HydrophobicContact CZ-CD2 4.17Å; F353-G549 CarbonylContact O-C 3.53Å; F353-G549 WeakPolarHBondContact O-CA 3.06Å; F353-W550 HydrophobicContact CB-CD2 3.65Å; F353-W550 HydrophobicContact CB-CE3 3.81Å; F353-W550 HydrophobicContact CB-CG 4.4Å; F353-W550 HydrophobicContact CB-CH2 3.43Å; F353-W550 VanDerWaalsContact CB-CH2 3.43Å; F353-W550 HydrophobicContact CB-CZ2 3.29Å; F353-W550 HydrophobicContact CB-CZ3 3.71Å; F353-W550 AromaticContact CD1-CE3 3.83Å; F353-W550 HydrophobicContact CD1-CE3 3.83Å; F353-W550 AromaticContact CD1-CH2 3.59Å; F353-W550 HydrophobicContact CD1-CH2 3.59Å; F353-W550 HydrophobicContact CD1-CZ2 4.36Å; F353-W550 AromaticContact CD1-CZ3 3.29Å; F353-W550 HydrophobicContact CD1-CZ3 3.29Å; F353-W550 HydrophobicContact CD2-CH2 4.2Å; F353-W550 HydrophobicContact CE1-CH2 4.41Å; F353-W550 HydrophobicContact CE1-CZ3 4.11Å; F353-W550 HydrophobicContact CG-CD2 4.49Å; F353-W550 HydrophobicContact CG-CE3 4.18Å; F353-W550 AromaticContact CG-CH2 3.47Å; F353-W550 HydrophobicContact CG-CH2 3.47Å; F353-W550 VanDerWaalsContact CG-CH2 3.47Å; F353-W550 AromaticContact CG-CZ2 3.86Å; F353-W550 HydrophobicContact CG-CZ2 3.86Å; F353-W550 AromaticContact CG-CZ3 3.67Å; F353-W550 HydrophobicContact CG-CZ3 3.67Å; F353-W550 PolarHBondContact N-O 2.88Å; F353-W550 PolarHBondContact O-N 2.69Å
354D88.1Confident75Confident29 Ų2982.3 Ų82.316%0.15546%0.456CS..EExtended strand (participates in β ladder)trans-132.8117.5171.4-174.4-18.1000109.4R356 T357 Q358 L560D354-R356 PolarHBondContact O-N 3.49Å; D354-R356 VanDerWaalsContact OD1-CB 3.27Å; D354-R356 WeakPolarHBondContact OD1-CB 3.28Å; D354-R356 WeakPolarHBondContact OD1-CG 3.36Å; D354-R356 IonicContact OD1-CZ 2.65Å; D354-R356 PolarHBondContact OD1-N 2.86Å; D354-R356 IonicContact OD1-NE 2.89Å; D354-R356 PolarHBondContact OD1-NE 3.22Å; D354-R356 IonicContact OD1-NH2 3.56Å; D354-R356 IonicContact OD2-CZ 3.38Å; D354-R356 IonicContact OD2-NE 3.99Å; D354-R356 PolarHBondContact OD2-NE 2.68Å; D354-R356 IonicContact OD2-NH2 3.65Å; D354-R356 PolarHBondContact OD2-NH2 2.97Å; D354-T357 HydrophobicContact CB-CG2 4.26Å; D354-T357 PolarHBondContact O-N 3.36Å; D354-T357 PolarHBondContact O-OG1 2.69Å; D354-Q358 PolarHBondContact O-N 2.93Å; D354-Q358 VanDerWaalsContact O-N 3.13Å; D354-L560 HydrophobicContact CB-CD1 4.28Å
355A79.6Confident75.4Confident0 Ų079.7 Ų79.70%044%0.442CS..Hα-helixtrans-56.1-27.2179.300000112.8F353 T357 W359 I366 P513 I548F353-A355 HydrophobicContact CE1-CB 4.23Å; A355-T357 VanDerWaalsContact C-N 3.34Å; A355-W359 HydrophobicContact CB-CE3 3.66Å; A355-W359 HydrophobicContact CB-CZ3 3.53Å; A355-W359 VanDerWaalsContact O-CE3 3.3Å; A355-W359 PolarHBondContact O-N 3.31Å; A355-I366 HydrophobicContact CB-CD1 4.11Å; A355-I366 HydrophobicContact CB-CG2 4.16Å; A355-P513 HydrophobicContact CB-CG 4.17Å; A355-I548 HydrophobicContact CB-CB 4.43Å; A355-I548 WeakPolarHBondContact CB-O 3.07Å; A355-I548 PolarHBondContact N-O 3.07Å
356R79.4Confident75.7Confident90 Ų9077.2 Ų77.234%0.3442%0.424SS..Hα-helixtrans-70.6-30.7178.9-59.7170.2-69.2-1740.9112.4D354 A363 I366 S367D354-R356 PolarHBondContact O-N 3.49Å; D354-R356 VanDerWaalsContact OD1-CB 3.27Å; D354-R356 WeakPolarHBondContact OD1-CB 3.28Å; D354-R356 WeakPolarHBondContact OD1-CG 3.36Å; D354-R356 IonicContact OD1-CZ 2.65Å; D354-R356 PolarHBondContact OD1-N 2.86Å; D354-R356 IonicContact OD1-NE 2.89Å; D354-R356 PolarHBondContact OD1-NE 3.22Å; D354-R356 IonicContact OD1-NH2 3.56Å; D354-R356 IonicContact OD2-CZ 3.38Å; D354-R356 IonicContact OD2-NE 3.99Å; D354-R356 PolarHBondContact OD2-NE 2.68Å; D354-R356 IonicContact OD2-NH2 3.65Å; D354-R356 PolarHBondContact OD2-NH2 2.97Å; R356-A363 HydrophobicContact CB-CB 4.24Å; R356-A363 WeakPolarHBondContact O-CB 3.38Å; R356-I366 HydrophobicContact CG-CB 4.01Å; R356-I366 HydrophobicContact CG-CG2 3.58Å; R356-S367 WeakPolarHBondContact CD-OG 3.32Å
357T80.3Confident76.4Confident105 Ų10574.9 Ų74.964%0.64440%0.401SS*.Hα-helixtrans-84.9-36.5177.360.70000110.8D354 A355D354-T357 HydrophobicContact CB-CG2 4.26Å; D354-T357 PolarHBondContact O-N 3.36Å; D354-T357 PolarHBondContact O-OG1 2.69Å; A355-T357 VanDerWaalsContact C-N 3.34Å
358Q80.6Confident76.1Confident100 Ų10076.4 Ų76.447%0.46741%0.407SS..Hα-helixtrans-67.2-42.3177.6-174.563.23300112.9F353 D354F353-Q358 HydrophobicContact CE2-CB 3.65Å; F353-Q358 HydrophobicContact CE2-CG 3.77Å; F353-Q358 HydrophobicContact CZ-CB 3.89Å; F353-Q358 HydrophobicContact CZ-CG 4.07Å; D354-Q358 PolarHBondContact O-N 2.93Å; D354-Q358 VanDerWaalsContact O-N 3.13Å
359W79.5Confident75.4Confident58 Ų5872.8 Ų72.822%0.2238%0.378CS..THydrogen-bonded Turntrans-116.270178.6-59.8-72.3000110.2F353 A355 E361 C362 A363 I366 L508 Y509 G512F353-W359 HydrophobicContact CE1-CH2 4.39Å; F353-W359 HydrophobicContact CE1-CZ3 4.11Å; F353-W359 AromaticContact CZ-CH2 3.69Å; F353-W359 HydrophobicContact CZ-CH2 3.69Å; F353-W359 AromaticContact CZ-CZ3 3.6Å; F353-W359 HydrophobicContact CZ-CZ3 3.6Å; A355-W359 HydrophobicContact CB-CE3 3.66Å; A355-W359 HydrophobicContact CB-CZ3 3.53Å; A355-W359 VanDerWaalsContact O-CE3 3.3Å; A355-W359 PolarHBondContact O-N 3.31Å; W359-E361 PolarHBondContact O-N 3.19Å; W359-C362 HydrophobicContact CB-CB 4.05Å; W359-C362 CarbonylContact O-C 3.39Å; W359-C362 WeakPolarHBondContact O-CA 3.43Å; W359-C362 PolarHBondContact O-N 3.37Å; W359-A363 PolarHBondContact O-N 3.41Å; W359-A363 VanDerWaalsContact O-N 3.11Å; W359-I366 HydrophobicContact CB-CD1 4.3Å; W359-I366 HydrophobicContact CE3-CD1 4.38Å; W359-L508 VanDerWaalsContact CH2-O 3.3Å; W359-L508 WeakPolarHBondContact CH2-O 3.13Å; W359-Y509 WeakPolarHBondContact CH2-O 3.47Å; W359-Y509 WeakPolarHBondContact CZ2-O 3.44Å; W359-G512 VanDerWaalsContact CH2-CA 3.45Å
360S74.2Confident74.1Confident87 Ų8772 Ų7261%0.60837%0.372SS*.G310 helixtrans-55.5-34.9-174.766.40000113.8C362 A363S360-C362 PolarHBondContact O-N 3.1Å; S360-A363 WeakPolarHBondContact O-CB 3.35Å; S360-A363 PolarHBondContact O-N 3.28Å
361E67.6Low72.5Confident148 Ų14871.7 Ų71.769%0.69237%0.368SS*.G310 helixtrans-67.3-22.7174.964.2-82-176.700113.6W359W359-E361 PolarHBondContact O-N 3.19Å
362C67Low70.8Confident51 Ų5165.2 Ų65.235%0.34534%0.338SS..G310 helixtrans-100.60.2175.7-66.10000112.7W359 S360 E364 L365 I366W359-C362 HydrophobicContact CB-CB 4.05Å; W359-C362 CarbonylContact O-C 3.39Å; W359-C362 WeakPolarHBondContact O-CA 3.43Å; W359-C362 PolarHBondContact O-N 3.37Å; S360-C362 PolarHBondContact O-N 3.1Å; C362-E364 VanDerWaalsContact C-N 3.28Å; C362-E364 PolarHBondContact O-N 2.85Å; C362-L365 WeakPolarHBondContact O-CB 3.05Å; C362-L365 PolarHBondContact O-N 2.89Å; C362-I366 HydrophobicContact CB-CD1 3.77Å; C362-I366 HydrophobicContact CB-CG1 4.2Å; C362-I366 WeakPolarHBondContact O-CG1 3.05Å; C362-I366 PolarHBondContact O-N 3.21Å
363A60.9Low69Low25 Ų2561.4 Ų61.421%0.20733%0.325CS..Hα-helixtrans-56.8-40.6-172.100000112.7R356 W359 S360 L365 I366 S367R356-A363 HydrophobicContact CB-CB 4.24Å; R356-A363 WeakPolarHBondContact O-CB 3.38Å; W359-A363 PolarHBondContact O-N 3.41Å; W359-A363 VanDerWaalsContact O-N 3.11Å; S360-A363 WeakPolarHBondContact O-CB 3.35Å; S360-A363 PolarHBondContact O-N 3.28Å; A363-L365 PolarHBondContact O-N 3.21Å; A363-I366 PolarHBondContact O-N 3.27Å; A363-S367 WeakPolarHBondContact O-CB 3.43Å; A363-S367 PolarHBondContact O-N 2.93Å; A363-S367 PolarHBondContact O-OG 3.2Å
364E61Low67Low175 Ų17566.9 Ų66.982%0.81835%0.354SS*.Hα-helixtrans-61.4-44176.1-68.9-166.5166.500111.9C362 S367 I368C362-E364 VanDerWaalsContact C-N 3.28Å; C362-E364 PolarHBondContact O-N 2.85Å; E364-S367 PolarHBondContact O-N 3.23Å; E364-I368 WeakPolarHBondContact O-CG1 3.45Å; E364-I368 PolarHBondContact O-N 2.86Å
365L60.5Low64.9Low79 Ų7966.7 Ų66.741%0.41436%0.355SS..Hα-helixtrans-67.7-44.4-179.9-173.372000111.6C362 A363 S367 I368 P384C362-L365 WeakPolarHBondContact O-CB 3.05Å; C362-L365 PolarHBondContact O-N 2.89Å; A363-L365 PolarHBondContact O-N 3.21Å; L365-S367 PolarHBondContact O-N 2.03Å; L365-I368 HydrophobicContact CD1-CD1 4.18Å; L365-I368 PolarHBondContact O-N 3.41Å; L365-P384 HydrophobicContact CD1-CB 4.02Å; L365-P384 HydrophobicContact CD2-CB 3.94Å; L365-P384 HydrophobicContact CD2-CG 4.46Å; L365-P384 HydrophobicContact CG-CB 4.14Å
366I63.1Low63.2Low13 Ų1368 Ų687%0.06737%0.368CS..Hα-helixtrans-66.1-30.9178.7-63166000110.7A355 R356 W359 C362 A363 I368 P513 R546 I548A355-I366 HydrophobicContact CB-CD1 4.11Å; A355-I366 HydrophobicContact CB-CG2 4.16Å; R356-I366 HydrophobicContact CG-CB 4.01Å; R356-I366 HydrophobicContact CG-CG2 3.58Å; W359-I366 HydrophobicContact CB-CD1 4.3Å; W359-I366 HydrophobicContact CE3-CD1 4.38Å; C362-I366 HydrophobicContact CB-CD1 3.77Å; C362-I366 HydrophobicContact CB-CG1 4.2Å; C362-I366 WeakPolarHBondContact O-CG1 3.05Å; C362-I366 PolarHBondContact O-N 3.21Å; A363-I366 PolarHBondContact O-N 3.27Å; I366-I368 VanDerWaalsContact C-N 3.31Å; I366-I368 PolarHBondContact O-N 2.92Å; I366-P513 HydrophobicContact CG1-CG 4.25Å; I366-P513 HydrophobicContact CG2-CG 4.16Å; I366-R546 PolarHBondContact O-NH2 3.38Å; I366-I548 HydrophobicContact CG2-CB 4.16Å; I366-I548 HydrophobicContact CG2-CG2 3.87Å
367S70.6Confident61.5Low58 Ų5865.4 Ų65.441%0.40636%0.364SS..THydrogen-bonded Turntrans-78.4-8.1179.5-59.90000114.3R356 A363 E364 L365 I369R356-S367 WeakPolarHBondContact CD-OG 3.32Å; A363-S367 WeakPolarHBondContact O-CB 3.43Å; A363-S367 PolarHBondContact O-N 2.93Å; A363-S367 PolarHBondContact O-OG 3.2Å; E364-S367 PolarHBondContact O-N 3.23Å; L365-S367 PolarHBondContact O-N 2.03Å; S367-I369 PolarHBondContact O-N 2.72Å; S367-I369 VanDerWaalsContact O-N 3.13Å
368I62.1Low59.3Low83 Ų8360.5 Ų60.543%0.42633%0.334SS..  trans-67.3113.7179-60.5-179.9000110.2E364 L365 I366 R546E364-I368 WeakPolarHBondContact O-CG1 3.45Å; E364-I368 PolarHBondContact O-N 2.86Å; L365-I368 HydrophobicContact CD1-CD1 4.18Å; L365-I368 PolarHBondContact O-N 3.41Å; I366-I368 VanDerWaalsContact C-N 3.31Å; I366-I368 PolarHBondContact O-N 2.92Å; I368-R546 PolarHBondContact O-NH2 2.81Å
369I65.4Low57.3Low41 Ų4165.1 Ų65.121%0.2135%0.348CS..  trans-85.1121166.5-56.6-55.3000108.4S367 A562 N563 G566 T567 N572S367-I369 PolarHBondContact O-N 2.72Å; S367-I369 VanDerWaalsContact O-N 3.13Å; I369-A562 HydrophobicContact CD1-CB 3.74Å; I369-N563 WeakPolarHBondContact CG2-O 3.23Å; I369-G566 WeakPolarHBondContact CG2-O 3.2Å; I369-T567 HydrophobicContact CB-CG2 4.46Å; I369-N572 WeakPolarHBondContact CG1-ND2 3.21Å
370K58Low55.2Low33 Ų3364.2 Ų64.214%0.14335%0.347CS..  trans-83.9160.1178.2-66-168.1177.7-1660111N380 V383 G386 S564 W565 G566K370-N380 PolarHBondContact NZ-O 3.31Å; K370-N380 VanDerWaalsContact NZ-O 3.14Å; K370-V383 PolarHBondContact NZ-O 3.47Å; K370-G386 PolarHBondContact NZ-O 2.7Å; K370-S564 CarbonylContact O-C 3.58Å; K370-S564 WeakPolarHBondContact O-CA 3.12Å; K370-W565 PolarHBondContact O-N 3.44Å; K370-G566 PolarHBondContact O-N 2.67Å
371D56.2Low53.1Low43 Ų4360.7 Ų60.723%0.2332%0.322CS..BIsolated β-bridgetrans-122.5115.3169-164.9-30.2000110.4R311 S373 L388 S564R311-D371 IonicContact CZ-OD1 2.89Å; R311-D371 VanDerWaalsContact CZ-OD1 3.26Å; R311-D371 IonicContact CZ-OD2 3.45Å; R311-D371 IonicContact NH1-OD1 2.79Å; R311-D371 PolarHBondContact NH1-OD1 3.36Å; R311-D371 IonicContact NH1-OD2 3.9Å; R311-D371 PolarHBondContact NH1-OD2 2.96Å; R311-D371 IonicContact NH2-OD1 3.32Å; R311-D371 PolarHBondContact NH2-OD1 3.26Å; D371-S373 PolarHBondContact O-N 3.49Å; D371-S373 WeakPolarHBondContact OD1-CA 3.43Å; D371-S373 PolarHBondContact OD1-N 3.4Å; D371-L388 HydrophobicContact CB-CD2 4.21Å; D371-L388 WeakPolarHBondContact O-CD2 3.29Å; D371-S564 CarbonylContact C-O 3.58Å; D371-S564 WeakPolarHBondContact CA-O 3.5Å
372Q53Low51.3Low17 Ų1755.8 Ų55.88%0.07931%0.311CS..  trans-71.6-4176.168.7176.6102.800113.8F323 N374 C375 H543 S564F323-Q372 HydrophobicContact CE2-CG 3.91Å; F323-Q372 HydrophobicContact CZ-CG 3.75Å; F323-Q372 PolarHBondContact O-NE2 2.01Å; Q372-N374 PolarHBondContact O-N 3.34Å; Q372-C375 PolarHBondContact NE2-O 2.89Å; Q372-C375 WeakPolarHBondContact O-CB 3.03Å; Q372-C375 PolarHBondContact O-N 3.42Å; Q372-H543 PolarHBondContact OE1-CE1 3.44Å; Q372-S564 WeakPolarHBondContact CG-O 3.04Å; Q372-S564 PolarHBondContact N-O 3.16Å; Q372-S564 PolarHBondContact OE1-OG 3.45Å
373S51.3Low49.5Very low42 Ų4256.9 Ų56.929%0.29432%0.316SS..THydrogen-bonded Turntrans49.1-135-173.1-62.50000110.6R311 F323 D371 C375 Y389R311-S373 PolarHBondContact NH2-O 2.86Å; R311-S373 VanDerWaalsContact NH2-O 3.07Å; F323-S373 WeakPolarHBondContact CE2-O 3.45Å; D371-S373 PolarHBondContact O-N 3.49Å; D371-S373 WeakPolarHBondContact OD1-CA 3.43Å; D371-S373 PolarHBondContact OD1-N 3.4Å; S373-C375 VanDerWaalsContact C-N 3.32Å; S373-Y389 WeakPolarHBondContact CB-O 3.47Å; S373-Y389 PolarHBondContact OG-O 3.5Å
374N49.4Very low47.8Very low127 Ų12759.4 Ų59.468%0.67933%0.33SS*.THydrogen-bonded Turntrans-93.816.2175.4-64.5-14.6000112.9Q372Q372-N374 PolarHBondContact O-N 3.34Å
375C44Very low46.1Very low25 Ų2556.4 Ų56.417%0.16932%0.324CS..  trans-93.8121.7-179.9-164.80000109.7Q372 S373 S377Q372-C375 PolarHBondContact NE2-O 2.89Å; Q372-C375 WeakPolarHBondContact O-CB 3.03Å; Q372-C375 PolarHBondContact O-N 3.42Å; S373-C375 VanDerWaalsContact C-N 3.32Å; C375-S377 PolarHBondContact O-N 2.82Å; C375-S377 PolarHBondContact SG-OG 2.88Å
376G44.2Very low44.4Very low27 Ų2753.8 Ų53.828%0.27832%0.316SS..  trans-71.315.7172.400000114.5A322 G325 C378A322-G376 VanDerWaalsContact O-CA 3.24Å; A322-G376 WeakPolarHBondContact O-CA 3.14Å; G325-G376 WeakPolarHBondContact CA-O 2.98Å; G376-C378 VanDerWaalsContact C-N 3.27Å; G376-C378 PolarHBondContact O-N 2.91Å
377S42Very low42.6Very low36 Ų3656 Ų5625%0.25234%0.342SS..  trans-81.269.9-179.865.90000111C375 W379C375-S377 PolarHBondContact O-N 2.82Å; C375-S377 PolarHBondContact SG-OG 2.88Å; S377-W379 PolarHBondContact O-N 3.29Å; S377-W379 VanDerWaalsContact O-N 3.16Å
378C33.9Very low40.4Very low3 Ų358 Ų582%0.0235%0.348CS..G310 helixtrans-68.4-9.5-179.2-64.60000114L324 G325 V326 G376 N380 T381L324-C378 PolarHBondContact O-SG 2.65Å; G325-C378 VanDerWaalsContact CA-SG 3.58Å; V326-C378 HydrophobicContact CG2-CB 4.06Å; G376-C378 VanDerWaalsContact C-N 3.27Å; G376-C378 PolarHBondContact O-N 2.91Å; C378-N380 PolarHBondContact O-N 3.38Å; C378-T381 PolarHBondContact O-N 2.72Å; C378-T381 PolarHBondContact O-OG1 2.78Å
379W39.3Very low38.7Very low197 Ų19758.7 Ų58.775%0.74635%0.346SS*.G310 helixtrans-60.8-11.7174.7-6483000114.5S377S377-W379 PolarHBondContact O-N 3.29Å; S377-W379 VanDerWaalsContact O-N 3.16Å
380N34.9Very low36.8Very low38 Ų3859.9 Ų59.920%0.20337%0.369CS..G310 helixtrans-87.91.2-177.9-85.8-37.3000115.9K370 C378 G382 Y389K370-N380 PolarHBondContact NZ-O 3.31Å; K370-N380 VanDerWaalsContact NZ-O 3.14Å; C378-N380 PolarHBondContact O-N 3.38Å; N380-G382 PolarHBondContact O-N 2.79Å; N380-Y389 WeakPolarHBondContact ND2-CE2 3.18Å
381T30.9Very low35.2Very low14 Ų1462.4 Ų62.49%0.08639%0.39CS..THydrogen-bonded Turntrans-71.5-25.5-175.450.10000113.9C378C378-T381 PolarHBondContact O-N 2.72Å; C378-T381 PolarHBondContact O-OG1 2.78Å
382G28.8Very low33.8Very low45 Ų4570 Ų7046%0.46442%0.421SS..THydrogen-bonded Turntrans-85.5-13.1-175.100000117.3N380N380-G382 PolarHBondContact O-N 2.79Å
383V30.9Very low32.4Very low73 Ų7375.9 Ų75.944%0.44245%0.449SS..  trans-106.4116.1-172.1-1710000110.9K370 T385K370-V383 PolarHBondContact NZ-O 3.47Å; V383-T385 PolarHBondContact O-N 3.43Å
384P25.1Very low31.1Very low78 Ų7876.8 Ų76.851%0.50647%0.465SS..THydrogen-bonded Turntrans-59.1-20.9-178.2-23.732.3000115.1L365L365-P384 HydrophobicContact CD1-CB 4.02Å; L365-P384 HydrophobicContact CD2-CB 3.94Å; L365-P384 HydrophobicContact CD2-CG 4.46Å; L365-P384 HydrophobicContact CG-CB 4.14Å
385T25.2Very low29.9Very low112 Ų11274 Ų7469%0.68745%0.454SS*.THydrogen-bonded Turntrans-108.13.4-17154.40000115.9V383V383-T385 PolarHBondContact O-N 3.43Å
386G25Very low28.9Very low25 Ų2581.8 Ų81.826%0.25849%0.486SS..  trans-81.8115.9179.800000113.9K370K370-G386 PolarHBondContact NZ-O 2.7Å
387G24.7Very low27.9Very low59 Ų5984.4 Ų84.461%0.60850%0.497SS*.PPolyproline II helixtrans-74.4161.5-176.100000116.6
388L25.3Very low27Very low99 Ų9993.2 Ų93.252%0.51853%0.527SS..PPolyproline II helixtrans-70.5123.5-170.7-62.7156.6000112.8D371D371-L388 HydrophobicContact CB-CD2 4.21Å; D371-L388 WeakPolarHBondContact O-CD2 3.29Å
389Y26.4Very low26.4Very low98 Ų9898 Ų9838%0.38456%0.561SS.*PPolyproline II helixtrans-83.4131.9177.2-74.2-98.5000111.5S373 N380 I455S373-Y389 WeakPolarHBondContact CB-O 3.47Å; S373-Y389 PolarHBondContact OG-O 3.5Å; N380-Y389 WeakPolarHBondContact ND2-CE2 3.18Å; Y389-I455 VanDerWaalsContact OH-CD1 3.23Å; Y389-I455 WeakPolarHBondContact OH-CD1 3.34Å
390G24.5Very low25.7Very low67 Ų6795.8 Ų95.869%0.69156%0.562SS**  trans-152.8103.9166.800000110.1
391S25Very low25.1Very low86 Ų8698.9 Ų98.960%0.60158%0.584SS**  trans-97.1150.2170.453.20000110.8E393S391-E393 PolarHBondContact O-N 3.39Å; S391-E393 PolarHBondContact OG-O 3.17Å
392K26.3Very low25Very low201 Ų201103.7 Ų103.787%0.87462%0.615SS**SBendtrans-66.8-10.1177.2-90.2-174.9171.5-174.90114.9
393E23.6Very low24.8Very low141 Ų141109.2 Ų109.266%0.65963%0.634SS**SBendtrans-123.4118.7-178.4-71.1168.1-172.300107S391 C395S391-E393 PolarHBondContact O-N 3.39Å; S391-E393 PolarHBondContact OG-O 3.17Å; E393-C395 PolarHBondContact O-N 3.25Å
394G24.8Very low24.5Very low61 Ų61112.3 Ų112.363%0.62965%0.648SS**  trans-57.5133.6177.800000110K396G394-K396 PolarHBondContact O-N 3.37Å
395C23.9Very low24.5Very low69 Ų69118.3 Ų118.347%0.46667%0.67SS.*  trans-59102.2169.5-650000108.4E393E393-C395 PolarHBondContact O-N 3.25Å
396K22.4Very low24.4Very low189 Ų189118.6 Ų118.682%0.82267%0.667SS**PPolyproline II helixtrans-76.9129.9164.6-76.9-170.5175.2-173.90108.5G394 Y398G394-K396 PolarHBondContact O-N 3.37Å; K396-Y398 PolarHBondContact O-N 2.88Å
397P23.2Very low24.4Very low81 Ų81124.3 Ų124.353%0.52668%0.684SS.*PPolyproline II helixtrans-71.9124178.526.4-30.1000110.2A322A322-P397 HydrophobicContact CB-CB 4.13Å; A322-P397 HydrophobicContact CB-CG 4.38Å
398Y22Very low24.5Very low221 Ų221126 Ų12687%0.86769%0.693SS**PPolyproline II helixtrans-85119.5166.2-107.5-86.3000108.9K396K396-Y398 PolarHBondContact O-N 2.88Å
399S22.8Very low24.5Very low105 Ų105128.1 Ų128.173%0.73470%0.7SS**PPolyproline II helixtrans-71.1123.1168.947.40000110.1P401S399-P401 WeakPolarHBondContact O-CD 3.3Å
400I23.2Very low24.6Very low150 Ų150127 Ų12777%0.76970%0.703SS**PPolyproline II helixtrans-84.4120173.1-58.3173.2000108.1
401P22.6Very low24.8Very low103 Ų103127.9 Ų127.967%0.66970%0.697SS**PPolyproline II helixtrans-74.7137.2165.6-10.427.1000110.1S399 N403S399-P401 WeakPolarHBondContact O-CD 3.3Å; P401-N403 PolarHBondContact O-N 3.27Å
402P28.5Very low25Very low115 Ų115127.7 Ų127.775%0.74770%0.701SS**SBendtrans-78.997.3-17931.3-29.6000108.4
403N24.6Very low25.2Very low161 Ų161121.7 Ų121.786%0.86168%0.684SS**  trans169.249153.1-85.2-12.4000112.1P401P401-N403 PolarHBondContact O-N 3.27Å
404N25.1Very low25.5Very low137 Ų137117.6 Ų117.673%0.73367%0.668SS**  trans-135.3109.2164.9-100.2-27.5000109.9N406N404-N406 PolarHBondContact O-N 2.89Å
405E25.3Very low25.6Very low205 Ų205118.5 Ų118.596%0.95866%0.655SS**  trans-65.322.4168.7-66-177.2152.900113.1
406N23.7Very low25.8Very low118 Ų118120.6 Ų120.663%0.63166%0.656SS**SBendtrans-120.3102.3-177.9-80.3-46.4000110.2N404N404-N406 PolarHBondContact O-N 2.89Å
407K24.1Very low26Very low144 Ų144113.2 Ų113.263%0.62663%0.628SS**  trans54107.1148.8-61.7172.4-176.3168.70115.4E409K407-E409 VanDerWaalsContact C-N 3.33Å; K407-E409 PolarHBondContact O-N 3.34Å
408A26.4Very low26.1Very low96 Ų96114.5 Ų114.579%0.79363%0.629SS**  trans-52.496.9160.300000109.7T410A408-T410 PolarHBondContact O-N 2.68Å
409E26.5Very low26.2Very low142 Ų142111 Ų11166%0.66462%0.62SS**PPolyproline II helixtrans-68.1118.3174.5-74.4-165.115100108K407 K415K407-E409 VanDerWaalsContact C-N 3.33Å; K407-E409 PolarHBondContact O-N 3.34Å; E409-K415 IonicContact OE1-NZ 2.78Å; E409-K415 PolarHBondContact OE1-NZ 2.91Å; E409-K415 IonicContact OE2-NZ 3.01Å; E409-K415 PolarHBondContact OE2-NZ 2.8Å
410T28.9Very low26.4Very low74 Ų74111.5 Ų111.545%0.45461%0.611SS.*PPolyproline II helixtrans-58142.2-179.1-33.20000109.4A408 T414A408-T410 PolarHBondContact O-N 2.68Å; T410-T414 VanDerWaalsContact CG2-CB 3.48Å; T410-T414 HydrophobicContact CG2-CG2 3.49Å; T410-T414 VanDerWaalsContact CG2-CG2 3.49Å; T410-T414 WeakPolarHBondContact CG2-OG1 3.47Å
411P28.8Very low26.5Very low87 Ų87110.5 Ų110.557%0.56560%0.599SS**PPolyproline II helixtrans-48.5154-172.1-29.734.9000113.3C413 T414 K415P411-C413 PolarHBondContact O-N 3.23Å; P411-T414 WeakPolarHBondContact O-CA 3.37Å; P411-T414 WeakPolarHBondContact O-CB 3.44Å; P411-T414 PolarHBondContact O-N 3.45Å; P411-K415 PolarHBondContact O-N 3.01Å
412A28.6Very low26.6Very low81 Ų81111.1 Ų111.167%0.66960%0.603SS**Hα-helixtrans-51-24.8-173.300000115.2T414 K415 K416A412-T414 VanDerWaalsContact C-N 3.27Å; A412-T414 PolarHBondContact O-N 2.89Å; A412-K415 PolarHBondContact O-N 2.85Å; A412-K416 PolarHBondContact O-N 3.46Å
413C30.1Very low26.4Very low76 Ų76111 Ų11151%0.51460%0.6SS.*Hα-helixtrans-64.4-28.6171.562.20000113.6P411P411-C413 PolarHBondContact O-N 3.23Å
414T29.8Very low26.4Very low54 Ų54109 Ų10933%0.33159%0.589SS.*Hα-helixtrans-90.9-35175-45.60000112.3T410 P411 A412 K416 C417 I418T410-T414 VanDerWaalsContact CG2-CB 3.48Å; T410-T414 HydrophobicContact CG2-CG2 3.49Å; T410-T414 VanDerWaalsContact CG2-CG2 3.49Å; T410-T414 WeakPolarHBondContact CG2-OG1 3.47Å; P411-T414 WeakPolarHBondContact O-CA 3.37Å; P411-T414 WeakPolarHBondContact O-CB 3.44Å; P411-T414 PolarHBondContact O-N 3.45Å; A412-T414 VanDerWaalsContact C-N 3.27Å; A412-T414 PolarHBondContact O-N 2.89Å; T414-K416 VanDerWaalsContact C-N 3.34Å; T414-K416 PolarHBondContact O-N 2.82Å; T414-C417 WeakPolarHBondContact O-CB 3.28Å; T414-C417 PolarHBondContact O-N 3.43Å; T414-I418 PolarHBondContact O-N 3.23Å
415K27.4Very low26.5Very low80 Ų80108 Ų10835%0.34858%0.583SS.*Hα-helixtrans-62.7-39.7178.3-157.2172.6-172.3170.50112.3E409 P411 A412 C417 I418 E419E409-K415 IonicContact OE1-NZ 2.78Å; E409-K415 PolarHBondContact OE1-NZ 2.91Å; E409-K415 IonicContact OE2-NZ 3.01Å; E409-K415 PolarHBondContact OE2-NZ 2.8Å; P411-K415 PolarHBondContact O-N 3.01Å; A412-K415 PolarHBondContact O-N 2.85Å; K415-C417 PolarHBondContact O-N 3Å; K415-C417 VanDerWaalsContact O-N 3.14Å; K415-I418 PolarHBondContact O-N 3.44Å; K415-I418 VanDerWaalsContact O-N 3.14Å; K415-E419 PolarHBondContact O-N 3.11Å
416K26.9Very low26.4Very low113 Ų113101.9 Ų101.949%0.49157%0.568SS.*Hα-helixtrans-63.8-16.9174.1-152.8172.1-172.6172.10113.6A412 T414A412-K416 PolarHBondContact O-N 3.46Å; T414-K416 VanDerWaalsContact C-N 3.34Å; T414-K416 PolarHBondContact O-N 2.82Å
417C27Very low26.6Very low35 Ų35104.3 Ų104.324%0.23657%0.573CS.*Hα-helixtrans-85.6-30.2174.2-85.30000113.9T414 K415 F454T414-C417 WeakPolarHBondContact O-CB 3.28Å; T414-C417 PolarHBondContact O-N 3.43Å; K415-C417 PolarHBondContact O-N 3Å; K415-C417 VanDerWaalsContact O-N 3.14Å; C417-F454 WeakPolarHBondContact SG-CE1 3.47Å; C417-F454 VanDerWaalsContact SG-CZ 3.51Å
418I25.8Very low26.7Very low108 Ų108103.7 Ų103.755%0.55458%0.576SS**Hα-helixtrans-75.2-37.5-180-62.1173.1000110T414 K415 Y421T414-I418 PolarHBondContact O-N 3.23Å; K415-I418 PolarHBondContact O-N 3.44Å; K415-I418 VanDerWaalsContact O-N 3.14Å; I418-Y421 CarbonylContact O-C 3.07Å; I418-Y421 PolarHBondContact O-N 3.05Å
419E24.9Very low26.7Very low146 Ų146108 Ų10868%0.68257%0.572SS**Hα-helixtrans-71.9-30.3-179-68.8175.2178.800113.1K415K415-E419 PolarHBondContact O-N 3.11Å
420E27.2Very low26.6Very low116 Ų116106 Ų10654%0.54257%0.573SS.*THydrogen-bonded Turntrans-82.1-10.7175.9-73.9-172.8178.100113.6
421Y25.3Very low26.6Very low129 Ų129110.3 Ų110.351%0.50659%0.586SS.*SBendtrans-14183178.4-74-80.7000111.2I418 V423 R445I418-Y421 CarbonylContact O-C 3.07Å; I418-Y421 PolarHBondContact O-N 3.05Å; Y421-V423 PolarHBondContact O-N 3.49Å; Y421-R445 PolarHBondContact OH-NH1 3.29Å; Y421-R445 PolarHBondContact OH-NH2 3.01Å
422P23Very low26.4Very low116 Ų116109.7 Ų109.775%0.75360%0.596SS**  trans-71.996.2178.729.5-31.9000109.2D424P422-D424 PolarHBondContact O-N 3.4Å
423V25.2Very low26.2Very low112 Ų112113.2 Ų113.268%0.67960%0.598SS**  trans-74.7120.5161-175.70000106.4Y421 L425Y421-V423 PolarHBondContact O-N 3.49Å; V423-L425 HydrophobicContact CB-CG 4.44Å; V423-L425 HydrophobicContact CG1-CG 4.2Å; V423-L425 PolarHBondContact O-N 3.47Å
424D24.3Very low25.9Very low121 Ų121117.7 Ų117.765%0.64762%0.617SS**  trans-70.671.4-178.9-165.22.8000111P422 A426P422-D424 PolarHBondContact O-N 3.4Å; D424-A426 PolarHBondContact O-N 3.36Å; D424-A426 WeakPolarHBondContact OD1-CB 3.45Å
425L26.4Very low26Very low114 Ų114117.8 Ų117.860%0.59762%0.617SS**THydrogen-bonded Turntrans-72.21.6178.1-75.7163.5000112.6V423 K427V423-L425 HydrophobicContact CB-CG 4.44Å; V423-L425 HydrophobicContact CG1-CG 4.2Å; V423-L425 PolarHBondContact O-N 3.47Å; L425-K427 VanDerWaalsContact C-N 3.3Å; L425-K427 PolarHBondContact O-N 2.94Å
426A25.1Very low25.9Very low77 Ų77118.1 Ų118.164%0.63662%0.623SS**THydrogen-bonded Turntrans-69.9-26.7177.900000112.4D424D424-A426 PolarHBondContact O-N 3.36Å; D424-A426 WeakPolarHBondContact OD1-CB 3.45Å
427K26.6Very low25.8Very low169 Ų169118.6 Ų118.674%0.73563%0.627SS**THydrogen-bonded Turntrans-76.7-28.4-179-85.3-176.9175.9175.10114.8L425 S430L425-K427 VanDerWaalsContact C-N 3.3Å; L425-K427 PolarHBondContact O-N 2.94Å; K427-S430 PolarHBondContact O-OG 2.88Å
428D26.3Very low25.8Very low132 Ų132124.2 Ų124.271%0.70665%0.647SS**G310 helixtrans-92.1-9.8-174.2-98.9-15.2000115.2S430D428-S430 PolarHBondContact O-N 3.46Å; D428-S430 VanDerWaalsContact O-N 3.1Å
429R25.7Very low25.8Very low186 Ų186122.4 Ų122.470%0.70264%0.637SS**G310 helixtrans-69.3-6.2177.1-76.4-171.6179.6163.69.7114.8K431R429-K431 VanDerWaalsContact C-N 3.27Å; R429-K431 PolarHBondContact O-N 3.22Å
430S26.3Very low25.9Very low99 Ų99118.8 Ų118.869%0.69263%0.632SS**G310 helixtrans-79-1.3-177.661.90000114.7K427 D428K427-S430 PolarHBondContact O-OG 2.88Å; D428-S430 PolarHBondContact O-N 3.46Å; D428-S430 VanDerWaalsContact O-N 3.1Å
431K27.8Very low25.8Very low165 Ų165114.7 Ų114.772%0.71761%0.613SS**SBendtrans-121.587.3178.9-64.9-175.2-178.5177.60110.8R429 H433R429-K431 VanDerWaalsContact C-N 3.27Å; R429-K431 PolarHBondContact O-N 3.22Å; K431-H433 PolarHBondContact O-N 3.21Å
432G24.6Very low25.8Very low75 Ų75112.4 Ų112.477%0.77361%0.612SS**  trans-65.791-174.400000114.9
433H24.9Very low25.9Very low154 Ų154108.2 Ų108.271%0.71359%0.585SS**  trans-130.7131.3169.5-69.2-72000111.8K431 V435K431-H433 PolarHBondContact O-N 3.21Å; H433-V435 HydrophobicContact CB-CG2 4.44Å
434N24.4Very low25.9Very low170 Ų170108 Ų10891%0.90958%0.577SS**  trans-85.6115.4177.3-75-31.4000110.4
435V30Very low26Very low57 Ų57108.9 Ų108.935%0.34557%0.571SS.*  trans-153.4152.9-178-163.10000114.4H433 H461H433-V435 HydrophobicContact CB-CG2 4.44Å; V435-H461 VanDerWaalsContact CB-CD2 3.44Å; V435-H461 WeakPolarHBondContact CB-CD2 2.96Å; V435-H461 HydrophobicContact CG1-CB 4.47Å
436N25.5Very low26Very low87 Ų87106.5 Ų106.547%0.46556%0.563SS.*  trans-104.4152.6-162.4-60-48000115.7
437E26.5Very low26.3Very low122 Ų122110.8 Ų110.857%0.5757%0.57SS**  trans94.9135.5166.1-60.4-170.8168.800120.6V460E437-V460 PolarHBondContact O-N 3.44Å
438K26.4Very low26.5Very low153 Ų153108.7 Ų108.767%0.66557%0.571SS**EExtended strand (participates in β ladder)trans-111.5130.7-170.2-68.1179.4179.1178.70113.1I457K438-I457 HydrophobicContact CB-CG2 3.94Å; K438-I457 HydrophobicContact CD-CG2 4.14Å; K438-I457 HydrophobicContact CG-CG2 4.14Å
439M25Very low26.6Very low70 Ų70107.6 Ų107.635%0.34557%0.569SS.*EExtended strand (participates in β ladder)trans-108.6135.2171-105.5178161.600111.1F441 I457 L458 V460 I490M439-F441 HydrophobicContact CB-CE2 4.14Å; M439-I457 WeakPolarHBondContact O-CA 3.39Å; M439-L458 PolarHBondContact N-O 3.42Å; M439-L458 PolarHBondContact O-N 3.31Å; M439-V460 HydrophobicContact CB-CG2 4.24Å; M439-I490 HydrophobicContact CE-CD1 4.43Å; M439-I490 HydrophobicContact CE-CG2 4Å
440A26.6Very low26.7Very low70 Ų70101.8 Ų101.858%0.57957%0.567SS**EExtended strand (participates in β ladder)trans-102.5124.4177.100000111.4I455A440-I455 HydrophobicContact CB-CG2 3.99Å
441F26.8Very low26.7Very low31 Ų31104.6 Ų104.614%0.13656%0.564CS.*EExtended strand (participates in β ladder)trans-103.9139.4175.7-62.9-94.6000110.6M439 I455 I456 L458 L471M439-F441 HydrophobicContact CB-CE2 4.14Å; F441-I455 VanDerWaalsContact O-CA 3.25Å; F441-I455 WeakPolarHBondContact O-CA 3.46Å; F441-I456 HydrophobicContact CB-CB 4.49Å; F441-I456 WeakPolarHBondContact CD2-O 3.43Å; F441-I456 PolarHBondContact N-O 3.1Å; F441-I456 PolarHBondContact O-N 3.1Å; F441-L458 HydrophobicContact CD2-CB 4.43Å; F441-L458 HydrophobicContact CD2-CD1 4.19Å; F441-L458 HydrophobicContact CD2-CG 4.14Å; F441-L458 HydrophobicContact CE2-CB 3.79Å; F441-L458 HydrophobicContact CE2-CD1 3.65Å; F441-L458 HydrophobicContact CE2-CG 3.8Å; F441-L458 HydrophobicContact CZ-CD1 4.03Å; F441-L471 HydrophobicContact CZ-CD2 4.31Å
442T25.1Very low26.6Very low81 Ų81101.8 Ų101.850%0.49755%0.552SS.*EExtended strand (participates in β ladder)trans-102.9107.6165.441.60000109.8
443C25.1Very low26.8Very low27 Ų27102.3 Ų102.318%0.18254%0.544CS..EExtended strand (participates in β ladder)trans-98.8124.2173.3-88.60000110.9F454C443-F454 PolarHBondContact N-O 2.96Å
444Q25.1Very low27.1Very low108 Ų10898.7 Ų98.751%0.50553%0.526SS..PPolyproline II helixtrans-98117.2162.7-90.4-176.3-22.100108.4
445R25.9Very low27.3Very low139 Ų13993.6 Ų93.653%0.52550%0.498SS..PPolyproline II helixtrans-82.9132.7171.2-164.2-179.6-173.7169.82109.7Y421Y421-R445 PolarHBondContact OH-NH1 3.29Å; Y421-R445 PolarHBondContact OH-NH2 3.01Å
446P26.9Very low27.1Very low65 Ų6594.8 Ų94.842%0.42250%0.502SS..PPolyproline II helixtrans-73.1122.6165.9-13.628.8000110.8I482P446-I482 WeakPolarHBondContact CD-O 3.1Å; P446-I482 WeakPolarHBondContact CG-O 3.46Å
447E30.1Very low27.3Very low167 Ų16795.6 Ų95.678%0.7851%0.505SS*.SBendtrans52.591.8134.9-61.2174.9-168.600117.1
448T32.1Very low27.3Very low125 Ų12593.8 Ų93.877%0.76750%0.498SS*.SBendtrans176.3-7.2136.632.60000113.8
449T28.3Very low27.2Very low109 Ų10991 Ų9167%0.66949%0.491SS*.SBendtrans-141.6125.8171.557.20000110.6Y451T449-Y451 PolarHBondContact O-N 3.14Å
450G28.4Very low27.4Very low64 Ų6489 Ų8966%0.6648%0.483SS*.SBendtrans-41.9128.1-173.500000115.9
451Y24.7Very low28Very low158 Ų15890.3 Ų90.362%0.6248%0.476SS*.  trans30.3102.2162-59.9-84.6000118.2T449 A593T449-Y451 PolarHBondContact O-N 3.14Å; Y451-A593 HydrophobicContact CE1-CB 3.67Å; Y451-A593 HydrophobicContact CE2-CB 3.88Å; Y451-A593 WeakPolarHBondContact OH-CB 3.15Å
452K27.4Very low28.3Very low106 Ų10695.9 Ų95.946%0.46150%0.503SS..  trans-144.897.5140.7-61.9-177-173171.80108.8F454K452-F454 HydrophobicContact CB-CD1 4.01Å; K452-F454 HydrophobicContact CB-CD2 3.59Å; K452-F454 HydrophobicContact CB-CE1 3.52Å; K452-F454 HydrophobicContact CB-CE2 3.09Å; K452-F454 HydrophobicContact CB-CG 4.1Å; K452-F454 HydrophobicContact CB-CZ 3.16Å; K452-F454 HydrophobicContact CD-CE1 3.41Å; K452-F454 VanDerWaalsContact CD-CE1 3.41Å; K452-F454 HydrophobicContact CD-CE2 3.74Å; K452-F454 HydrophobicContact CD-CZ 2.94Å; K452-F454 HydrophobicContact CG-CE1 3.94Å; K452-F454 HydrophobicContact CG-CE2 4Å; K452-F454 HydrophobicContact CG-CZ 3.6Å; K452-F454 WeakPolarHBondContact O-CD2 3.37Å; K452-F454 PolarHBondContact O-N 3.45Å
453S27.5Very low28.8Very low86 Ų8696.9 Ų96.960%0.60151%0.511SS*.  trans-72.5113.8160-57.90000105.8
454F30.5Very low29.1Very low78 Ų7897.6 Ų97.634%0.34252%0.516SS..EExtended strand (participates in β ladder)trans-108.8139.7-177.7-61.8-78.8000110.6C417 C443 K452C417-F454 WeakPolarHBondContact SG-CE1 3.47Å; C417-F454 VanDerWaalsContact SG-CZ 3.51Å; C443-F454 PolarHBondContact N-O 2.96Å; K452-F454 HydrophobicContact CB-CD1 4.01Å; K452-F454 HydrophobicContact CB-CD2 3.59Å; K452-F454 HydrophobicContact CB-CE1 3.52Å; K452-F454 HydrophobicContact CB-CE2 3.09Å; K452-F454 HydrophobicContact CB-CG 4.1Å; K452-F454 HydrophobicContact CB-CZ 3.16Å; K452-F454 HydrophobicContact CD-CE1 3.41Å; K452-F454 VanDerWaalsContact CD-CE1 3.41Å; K452-F454 HydrophobicContact CD-CE2 3.74Å; K452-F454 HydrophobicContact CD-CZ 2.94Å; K452-F454 HydrophobicContact CG-CE1 3.94Å; K452-F454 HydrophobicContact CG-CE2 4Å; K452-F454 HydrophobicContact CG-CZ 3.6Å; K452-F454 WeakPolarHBondContact O-CD2 3.37Å; K452-F454 PolarHBondContact O-N 3.45Å
455I29.1Very low29.8Very low63 Ų6397.3 Ų97.332%0.32352%0.524SS..EExtended strand (participates in β ladder)trans-87110.3165.4-58.1-178.9000106.6Y389 A440 F441 I457Y389-I455 VanDerWaalsContact OH-CD1 3.23Å; Y389-I455 WeakPolarHBondContact OH-CD1 3.34Å; A440-I455 HydrophobicContact CB-CG2 3.99Å; F441-I455 VanDerWaalsContact O-CA 3.25Å; F441-I455 WeakPolarHBondContact O-CA 3.46Å; I455-I457 HydrophobicContact CG2-CG1 4Å
456I27.2Very low30.4Very low82 Ų8297.1 Ų97.142%0.42153%0.529SS..EExtended strand (participates in β ladder)trans-86.3120.8164.6-57.6177.6000105.1F441 L458F441-I456 HydrophobicContact CB-CB 4.49Å; F441-I456 WeakPolarHBondContact CD2-O 3.43Å; F441-I456 PolarHBondContact N-O 3.1Å; F441-I456 PolarHBondContact O-N 3.1Å; I456-L458 HydrophobicContact CG2-CD2 3.7Å; I456-L458 HydrophobicContact CG2-CG 3.83Å
457I28.2Very low31Very low103 Ų10395.7 Ų95.753%0.52852%0.517SS..EExtended strand (participates in β ladder)trans-95108.2167.8-57.9176.3000105.1K438 M439 I455K438-I457 HydrophobicContact CB-CG2 3.94Å; K438-I457 HydrophobicContact CD-CG2 4.14Å; K438-I457 HydrophobicContact CG-CG2 4.14Å; M439-I457 WeakPolarHBondContact O-CA 3.39Å; I455-I457 HydrophobicContact CG2-CG1 4Å
458L26.1Very low31.5Very low84 Ų8492.4 Ų92.444%0.4451%0.505SS..EExtended strand (participates in β ladder)trans-92.6133.3167.9-59.5173.5000107.6M439 F441 I456 V460M439-L458 PolarHBondContact N-O 3.42Å; M439-L458 PolarHBondContact O-N 3.31Å; F441-L458 HydrophobicContact CD2-CB 4.43Å; F441-L458 HydrophobicContact CD2-CD1 4.19Å; F441-L458 HydrophobicContact CD2-CG 4.14Å; F441-L458 HydrophobicContact CE2-CB 3.79Å; F441-L458 HydrophobicContact CE2-CD1 3.65Å; F441-L458 HydrophobicContact CE2-CG 3.8Å; F441-L458 HydrophobicContact CZ-CD1 4.03Å; I456-L458 HydrophobicContact CG2-CD2 3.7Å; I456-L458 HydrophobicContact CG2-CG 3.83Å; L458-V460 VanDerWaalsContact C-N 3.34Å; L458-V460 HydrophobicContact CB-CG2 3.62Å; L458-V460 PolarHBondContact O-N 2.84Å; L458-V460 VanDerWaalsContact O-N 3.12Å
459D25.4Very low32Very low96 Ų9690.5 Ų90.551%0.51349%0.494SS..EExtended strand (participates in β ladder)trans-78.786.1173.3-135.80.4000106.9H461D459-H461 PolarHBondContact O-N 3.11Å; D459-H461 PolarHBondContact O-ND1 2.65Å
460V29.8Very low32.5Very low27 Ų2790.1 Ų90.116%0.16449%0.487CS..  trans-95.2100.1-168.9-1710000109.2E437 M439 L458 Q462 L467E437-V460 PolarHBondContact O-N 3.44Å; M439-V460 HydrophobicContact CB-CG2 4.24Å; L458-V460 VanDerWaalsContact C-N 3.34Å; L458-V460 HydrophobicContact CB-CG2 3.62Å; L458-V460 PolarHBondContact O-N 2.84Å; L458-V460 VanDerWaalsContact O-N 3.12Å; V460-Q462 PolarHBondContact O-N 3.35Å; V460-L467 HydrophobicContact CG1-CD1 4.22Å; V460-L467 HydrophobicContact CG1-CD2 3.2Å; V460-L467 HydrophobicContact CG1-CG 4.14Å
461H38.5Very low33.2Very low97 Ų9788.9 Ų88.945%0.44947%0.465SS..  trans-59.6100.2176-71.543.1000110.7V435 D459V435-H461 VanDerWaalsContact CB-CD2 3.44Å; V435-H461 WeakPolarHBondContact CB-CD2 2.96Å; V435-H461 HydrophobicContact CG1-CB 4.47Å; D459-H461 PolarHBondContact O-N 3.11Å; D459-H461 PolarHBondContact O-ND1 2.65Å
462Q32.2Very low33.9Very low149 Ų14988.2 Ų88.270%0.69647%0.465SS*.  trans44.4122.4172.6-67.1-163.9-17.800118.6V460 S464 L467V460-Q462 PolarHBondContact O-N 3.35Å; Q462-S464 PolarHBondContact O-N 3.38Å; Q462-L467 WeakPolarHBondContact O-CD2 3.33Å
463P35.7Very low34.4Very low102 Ų10286.4 Ų86.466%0.66246%0.463SS*.  trans-72.594.9179.330.7-33.1000111.4
464S32Very low35Very low42 Ų4284.7 Ų84.729%0.29445%0.449SS..  trans-80.6154.9159.688.40000109.8Q462 E466 L467 N468Q462-S464 PolarHBondContact O-N 3.38Å; S464-E466 WeakPolarHBondContact CB-OE2 3.29Å; S464-E466 PolarHBondContact O-N 3.46Å; S464-E466 VanDerWaalsContact O-N 3.16Å; S464-E466 WeakPolarHBondContact OG-CB 3.39Å; S464-E466 PolarHBondContact OG-N 3.31Å; S464-E466 PolarHBondContact OG-OE2 3.16Å; S464-L467 WeakPolarHBondContact O-CA 3.03Å; S464-L467 WeakPolarHBondContact O-CB 3.12Å; S464-L467 PolarHBondContact O-N 3.21Å; S464-L467 PolarHBondContact OG-N 3.3Å; S464-N468 PolarHBondContact O-N 3.22Å
465P40.3Very low35.3Very low102 Ų10285.5 Ų85.566%0.66246%0.456SS*.Hα-helixtrans-53.1-31169.9-25.234.6000112.6L467 T469P465-L467 VanDerWaalsContact C-N 3.34Å; P465-T469 PolarHBondContact O-N 2.87Å; P465-T469 PolarHBondContact O-OG1 3Å
466E37.4Very low35.6Very low135 Ų13589.4 Ų89.463%0.63147%0.472SS*.Hα-helixtrans-65.2-34.3172-58.189-170.600112.3S464 T469 L470S464-E466 WeakPolarHBondContact CB-OE2 3.29Å; S464-E466 PolarHBondContact O-N 3.46Å; S464-E466 VanDerWaalsContact O-N 3.16Å; S464-E466 WeakPolarHBondContact OG-CB 3.39Å; S464-E466 PolarHBondContact OG-N 3.31Å; S464-E466 PolarHBondContact OG-OE2 3.16Å; E466-T469 CarbonylContact O-C 3.53Å; E466-T469 WeakPolarHBondContact O-CB 3.43Å; E466-T469 PolarHBondContact O-N 2.95Å; E466-L470 VanDerWaalsContact O-CB 3.27Å; E466-L470 WeakPolarHBondContact O-CB 3.22Å; E466-L470 PolarHBondContact O-N 3.04Å
467L40.7Very low35.8Very low35 Ų3590.2 Ų90.218%0.18347%0.474CS..Hα-helixtrans-70.6-38.3178.1-176.163000112.9V460 Q462 S464 P465 T469 L470 L471V460-L467 HydrophobicContact CG1-CD1 4.22Å; V460-L467 HydrophobicContact CG1-CD2 3.2Å; V460-L467 HydrophobicContact CG1-CG 4.14Å; Q462-L467 WeakPolarHBondContact O-CD2 3.33Å; S464-L467 WeakPolarHBondContact O-CA 3.03Å; S464-L467 WeakPolarHBondContact O-CB 3.12Å; S464-L467 PolarHBondContact O-N 3.21Å; S464-L467 PolarHBondContact OG-N 3.3Å; P465-L467 VanDerWaalsContact C-N 3.34Å; L467-T469 PolarHBondContact O-N 3.19Å; L467-L470 HydrophobicContact CD1-CD2 4.29Å; L467-L470 PolarHBondContact O-N 2.89Å; L467-L471 HydrophobicContact CD1-CD1 4.42Å; L467-L471 HydrophobicContact CD1-CG 4.39Å; L467-L471 HydrophobicContact CG-CD1 4.07Å; L467-L471 VanDerWaalsContact O-CB 3.28Å; L467-L471 WeakPolarHBondContact O-CB 3.38Å; L467-L471 WeakPolarHBondContact O-CG 3.33Å; L467-L471 PolarHBondContact O-N 3.08Å
468N41.1Very low36Very low97 Ų9790.3 Ų90.352%0.51948%0.482SS..Hα-helixtrans-62.9-35171.5-81.4-33.3000111.5S464 K472S464-N468 PolarHBondContact O-N 3.22Å; N468-K472 PolarHBondContact O-N 2.89Å; N468-K472 VanDerWaalsContact O-N 3.17Å
469T41.8Very low36.1Very low86 Ų8693.6 Ų93.653%0.52850%0.499SS..Hα-helixtrans-71-47.3175.4-530000110.3P465 E466 L467 L471 K472 T473P465-T469 PolarHBondContact O-N 2.87Å; P465-T469 PolarHBondContact O-OG1 3Å; E466-T469 CarbonylContact O-C 3.53Å; E466-T469 WeakPolarHBondContact O-CB 3.43Å; E466-T469 PolarHBondContact O-N 2.95Å; L467-T469 PolarHBondContact O-N 3.19Å; T469-L471 PolarHBondContact O-N 3.07Å; T469-K472 CarbonylContact O-C 3.58Å; T469-K472 WeakPolarHBondContact O-CA 3.47Å; T469-K472 VanDerWaalsContact O-CB 3.31Å; T469-K472 WeakPolarHBondContact O-CB 3.24Å; T469-K472 PolarHBondContact O-N 3.47Å; T469-K472 VanDerWaalsContact O-N 3.16Å; T469-T473 PolarHBondContact O-N 3Å; T469-T473 PolarHBondContact O-OG1 3.04Å
470L39.6Very low36.5Very low100 Ų10095.4 Ų95.452%0.52450%0.5SS..Hα-helixtrans-61.4-41.9177.3-169.875.9000111.6E466 L467 T473 V474E466-L470 VanDerWaalsContact O-CB 3.27Å; E466-L470 WeakPolarHBondContact O-CB 3.22Å; E466-L470 PolarHBondContact O-N 3.04Å; L467-L470 HydrophobicContact CD1-CD2 4.29Å; L467-L470 PolarHBondContact O-N 2.89Å; L470-T473 CarbonylContact O-C 3.47Å; L470-T473 PolarHBondContact O-N 3.12Å; L470-T473 VanDerWaalsContact O-N 3.15Å; L470-V474 HydrophobicContact CG-CG2 4.21Å; L470-V474 WeakPolarHBondContact O-CB 3.34Å; L470-V474 WeakPolarHBondContact O-CG2 3.41Å; L470-V474 PolarHBondContact O-N 2.89Å
471L41.3Very low36.5Very low38 Ų3898 Ų9820%0.19952%0.519CS..Hα-helixtrans-62.7-42.5174.7-82.4163.3000111F441 L467 T469 I475F441-L471 HydrophobicContact CZ-CD2 4.31Å; L467-L471 HydrophobicContact CD1-CD1 4.42Å; L467-L471 HydrophobicContact CD1-CG 4.39Å; L467-L471 HydrophobicContact CG-CD1 4.07Å; L467-L471 VanDerWaalsContact O-CB 3.28Å; L467-L471 WeakPolarHBondContact O-CB 3.38Å; L467-L471 WeakPolarHBondContact O-CG 3.33Å; L467-L471 PolarHBondContact O-N 3.08Å; T469-L471 PolarHBondContact O-N 3.07Å; L471-I475 VanDerWaalsContact O-CB 3.28Å; L471-I475 WeakPolarHBondContact O-CB 3.43Å; L471-I475 VanDerWaalsContact O-CD1 3.29Å; L471-I475 WeakPolarHBondContact O-CD1 3.31Å; L471-I475 WeakPolarHBondContact O-CG1 3.28Å; L471-I475 PolarHBondContact O-N 2.73Å
472K40.3Very low36.1Very low145 Ų14597.9 Ų97.963%0.6352%0.521SS*.Hα-helixtrans-58.2-46.9169.8-102.3-175.9173.3-176.30111.4N468 T469 I475 E476N468-K472 PolarHBondContact O-N 2.89Å; N468-K472 VanDerWaalsContact O-N 3.17Å; T469-K472 CarbonylContact O-C 3.58Å; T469-K472 WeakPolarHBondContact O-CA 3.47Å; T469-K472 VanDerWaalsContact O-CB 3.31Å; T469-K472 WeakPolarHBondContact O-CB 3.24Å; T469-K472 PolarHBondContact O-N 3.47Å; T469-K472 VanDerWaalsContact O-N 3.16Å; K472-I475 PolarHBondContact O-N 3.24Å; K472-E476 WeakPolarHBondContact O-CB 3.46Å; K472-E476 VanDerWaalsContact O-CG 3.24Å; K472-E476 WeakPolarHBondContact O-CG 3.46Å; K472-E476 PolarHBondContact O-N 3.46Å
473T38.6Very low36Very low68 Ų6892.9 Ų92.942%0.41750%0.502SS..Hα-helixtrans-67.3-39.6-178.4-39.80000112.9T469 L470 E476 Q477T469-T473 PolarHBondContact O-N 3Å; T469-T473 PolarHBondContact O-OG1 3.04Å; L470-T473 CarbonylContact O-C 3.47Å; L470-T473 PolarHBondContact O-N 3.12Å; L470-T473 VanDerWaalsContact O-N 3.15Å; T473-E476 CarbonylContact O-C 3.6Å; T473-E476 PolarHBondContact O-N 3.22Å; T473-Q477 VanDerWaalsContact O-CG 3.25Å; T473-Q477 WeakPolarHBondContact O-CG 3.25Å; T473-Q477 PolarHBondContact O-N 3.06Å; T473-Q477 VanDerWaalsContact O-N 3.09Å
474V38.9Very low35.6Very low49 Ų4998.1 Ų98.130%0.29751%0.508SS..Hα-helixtrans-67.4-41.4177.4170.10000110.3L470 E476 Q477 Y480L470-V474 HydrophobicContact CG-CG2 4.21Å; L470-V474 WeakPolarHBondContact O-CB 3.34Å; L470-V474 WeakPolarHBondContact O-CG2 3.41Å; L470-V474 PolarHBondContact O-N 2.89Å; V474-E476 VanDerWaalsContact C-N 3.3Å; V474-E476 PolarHBondContact O-N 3.48Å; V474-Q477 PolarHBondContact O-N 3.22Å; V474-Y480 HydrophobicContact CG1-CD2 4.01Å; V474-Y480 HydrophobicContact CG1-CE2 3.73Å; V474-Y480 WeakPolarHBondContact O-CB 3.23Å; V474-Y480 WeakPolarHBondContact O-CD2 3.25Å
475I37Very low35.5Very low95 Ų9598.9 Ų98.949%0.48751%0.511SS..Hα-helixtrans-66.2-33.3174.2-68.2166.6000111.3L471 K472 Q477L471-I475 VanDerWaalsContact O-CB 3.28Å; L471-I475 WeakPolarHBondContact O-CB 3.43Å; L471-I475 VanDerWaalsContact O-CD1 3.29Å; L471-I475 WeakPolarHBondContact O-CD1 3.31Å; L471-I475 WeakPolarHBondContact O-CG1 3.28Å; L471-I475 PolarHBondContact O-N 2.73Å; K472-I475 PolarHBondContact O-N 3.24Å; I475-Q477 VanDerWaalsContact C-N 3.35Å
476E35.2Very low34.8Very low145 Ų145102.9 Ų102.968%0.67852%0.518SS*.Hα-helixtrans-81.1-8.1177.9-73.6172.8-175.200113.9K472 T473 V474K472-E476 WeakPolarHBondContact O-CB 3.46Å; K472-E476 VanDerWaalsContact O-CG 3.24Å; K472-E476 WeakPolarHBondContact O-CG 3.46Å; K472-E476 PolarHBondContact O-N 3.46Å; T473-E476 CarbonylContact O-C 3.6Å; T473-E476 PolarHBondContact O-N 3.22Å; V474-E476 VanDerWaalsContact C-N 3.3Å; V474-E476 PolarHBondContact O-N 3.48Å
477Q32Very low34.3Very low99 Ų99100.7 Ų100.746%0.46352%0.517SS..SBendtrans-69142.9176.6-70.4-145.7-14.100112.2T473 V474 I475 L479 Y480 S481T473-Q477 VanDerWaalsContact O-CG 3.25Å; T473-Q477 WeakPolarHBondContact O-CG 3.25Å; T473-Q477 PolarHBondContact O-N 3.06Å; T473-Q477 VanDerWaalsContact O-N 3.09Å; V474-Q477 PolarHBondContact O-N 3.22Å; I475-Q477 VanDerWaalsContact C-N 3.35Å; Q477-L479 PolarHBondContact O-N 3.32Å; Q477-L479 VanDerWaalsContact O-N 3.09Å; Q477-Y480 PolarHBondContact O-N 3.44Å; Q477-S481 PolarHBondContact O-N 2.79Å
478P31.6Very low34.1Very low106 Ų106102.7 Ų102.769%0.68853%0.528SS*.G310 helixtrans-57.8-30.2-176.5-22.431000113.9Y480 S481P478-Y480 PolarHBondContact O-N 3.22Å; P478-S481 WeakPolarHBondContact O-CB 3.44Å; P478-S481 PolarHBondContact O-N 2.79Å; P478-S481 PolarHBondContact O-OG 3.12Å
479L29.6Very low33.8Very low152 Ų152103.8 Ų103.880%0.79654%0.538SS*.G310 helixtrans-67.3-23.2176.2-81.2155.2000113.1Q477Q477-L479 PolarHBondContact O-N 3.32Å; Q477-L479 VanDerWaalsContact O-N 3.09Å
480Y33.5Very low33.7Very low135 Ų135104.6 Ų104.653%0.52954%0.538SS..G310 helixtrans-99.7-3.5176-76.4-84.8000113.9V474 Q477 P478 I482 C483V474-Y480 HydrophobicContact CG1-CD2 4.01Å; V474-Y480 HydrophobicContact CG1-CE2 3.73Å; V474-Y480 WeakPolarHBondContact O-CB 3.23Å; V474-Y480 WeakPolarHBondContact O-CD2 3.25Å; Q477-Y480 PolarHBondContact O-N 3.44Å; P478-Y480 PolarHBondContact O-N 3.22Å; Y480-I482 PolarHBondContact O-N 3.19Å; Y480-C483 PolarHBondContact O-N 3.33Å
481S29.4Very low33.7Very low80 Ų80102.9 Ų102.956%0.55955%0.545SS*.THydrogen-bonded Turntrans-59.9-9.1179.568.50000114.7Q477 P478Q477-S481 PolarHBondContact O-N 2.79Å; P478-S481 WeakPolarHBondContact O-CB 3.44Å; P478-S481 PolarHBondContact O-N 2.79Å; P478-S481 PolarHBondContact O-OG 3.12Å
482I30.8Very low33.8Very low96 Ų96111.6 Ų111.649%0.49258%0.581SS.*THydrogen-bonded Turntrans-83.7-15.6177.7-40.5178000112P446 Y480P446-I482 WeakPolarHBondContact CD-O 3.1Å; P446-I482 WeakPolarHBondContact CG-O 3.46Å; Y480-I482 PolarHBondContact O-N 3.19Å
483C28.9Very low34.4Very low44 Ų44111.5 Ų111.530%0.29758%0.577SS.*  trans-11280.5178.4-81.40000111.6Y480 V485Y480-C483 PolarHBondContact O-N 3.33Å; C483-V485 PolarHBondContact O-N 3.36Å
484R26.9Very low35.1Very low211 Ų211111.4 Ų111.480%0.79659%0.589SS**  trans-74.192.7169.8-75.4-169.1-177.4-174.91.7110.2K486R484-K486 PolarHBondContact O-N 3.46Å
485V30Very low36.1Very low59 Ų59112.8 Ų112.836%0.35859%0.59SS.*  trans-59.7106.7167.3-179.80000108.4C483 S487 L488C483-V485 PolarHBondContact O-N 3.36Å; V485-S487 VanDerWaalsContact C-N 3.34Å; V485-S487 PolarHBondContact O-N 3.07Å; V485-L488 HydrophobicContact CG1-CB 4.04Å
486K26.6Very low37.5Very low186 Ų186115 Ų11581%0.80959%0.592SS**SBendtrans-67.1-31.8-177.4-85-173.9175.5179.10113.5R484R484-K486 PolarHBondContact O-N 3.46Å
487S27.1Very low39Very low88 Ų88109.8 Ų109.862%0.61557%0.568SS**  trans-161.5126.3173.863.10000110V485V485-S487 VanDerWaalsContact C-N 3.34Å; V485-S487 PolarHBondContact O-N 3.07Å
488L34.9Very low40.9Very low78 Ų78105.5 Ų105.541%0.40855%0.549SS..  trans-107.3117.3172.6-175.169.3000108.1V485 I490V485-L488 HydrophobicContact CG1-CB 4.04Å; L488-I490 HydrophobicContact CD2-CD1 3.67Å; L488-I490 HydrophobicContact CD2-CG1 3.71Å; L488-I490 HydrophobicContact CG-CD1 4.28Å; L488-I490 HydrophobicContact CG-CG1 3.75Å
489T35.8Very low42.8Very low119 Ų119105 Ų10573%0.7356%0.555SS**  trans-98.4100.5173-50.90000108.1
490I39.2Very low45.1Very low103 Ų103100.5 Ų100.553%0.52853%0.534SS..  trans-89.5124.3175.9-53.9177.9000108M439 L488M439-I490 HydrophobicContact CE-CD1 4.43Å; M439-I490 HydrophobicContact CE-CG2 4Å; L488-I490 HydrophobicContact CD2-CD1 3.67Å; L488-I490 HydrophobicContact CD2-CG1 3.71Å; L488-I490 HydrophobicContact CG-CD1 4.28Å; L488-I490 HydrophobicContact CG-CG1 3.75Å
491G40.9Very low47.5Very low64 Ų6498.4 Ų98.466%0.6653%0.529SS*.  trans-64.8140.3172.200000110.8R493G491-R493 VanDerWaalsContact C-N 3.29Å; G491-R493 PolarHBondContact O-N 2.98Å
492K43.4Very low50Low222 Ų222100.8 Ų100.897%0.96553%0.531SS*.SBendtrans-63-34.2179.5-72-176.6178.6178.50113
493R52Low52.4Low143 Ų14396.7 Ų96.754%0.5451%0.512SS..  trans-165.2144.3-175.7-169.5176.3179.3-165.7-0.8110.8E339 G491 Y495E339-R493 IonicContact OE1-CZ 3.87Å; E339-R493 IonicContact OE1-NH2 2.81Å; E339-R493 PolarHBondContact OE1-NH2 2.93Å; E339-R493 IonicContact OE2-CZ 2.74Å; E339-R493 IonicContact OE2-NH2 3.62Å; E339-R493 PolarHBondContact OE2-NH2 3.16Å; G491-R493 VanDerWaalsContact C-N 3.29Å; G491-R493 PolarHBondContact O-N 2.98Å; R493-Y495 HydrophobicContact CG-CD1 4.33Å
494G53.2Low55.1Low66 Ų6696.3 Ų96.368%0.6851%0.506SS*.  trans-107.4140.2164.100000110.3
495Y60.5Low57.9Low78 Ų7887.3 Ų87.331%0.30647%0.473SS..  trans-150.2158.2179.551.3-91.8000110.2I341 R493 I497 Q507I341-Y495 HydrophobicContact CD1-CD1 4.15Å; I341-Y495 HydrophobicContact CD1-CD2 3.43Å; I341-Y495 VanDerWaalsContact CD1-CD2 3.43Å; I341-Y495 HydrophobicContact CD1-CE1 4.48Å; I341-Y495 HydrophobicContact CD1-CE2 3.82Å; I341-Y495 HydrophobicContact CD1-CG 3.62Å; I341-Y495 HydrophobicContact CG1-CD2 4.01Å; I341-Y495 HydrophobicContact CG1-CG 4.27Å; R493-Y495 HydrophobicContact CG-CD1 4.33Å; Y495-I497 HydrophobicContact CD2-CG1 4.24Å; Y495-I497 HydrophobicContact CE2-CG1 4.04Å; Y495-Q507 PolarHBondContact OH-OE1 2.58Å
496R65Low60.4Low142 Ų14285.2 Ų85.254%0.53646%0.459SS..EExtended strand (participates in β ladder)trans-90.3135.7172.6-176.5175178170.6-1.1108.7I338 E339 T340 I341I338-R496 HydrophobicContact CG2-CB 4.24Å; E339-R496 PolarHBondContact O-N 2.69Å; T340-R496 CarbonylContact C-O 3.15Å; T340-R496 WeakPolarHBondContact CA-O 3.42Å; I341-R496 PolarHBondContact N-O 3.39Å
497I68.7Low63.1Low35 Ų3577.1 Ų77.118%0.17942%0.424CS..EExtended strand (participates in β ladder)trans-89.3133.9170.5-52.2173.6000106.9Y495 A499 A503 M504 Q507 I514Y495-I497 HydrophobicContact CD2-CG1 4.24Å; Y495-I497 HydrophobicContact CE2-CG1 4.04Å; I497-A499 PolarHBondContact O-N 3.3Å; I497-A503 HydrophobicContact CG2-CB 3.85Å; I497-M504 HydrophobicContact CG2-CG 4.24Å; I497-Q507 HydrophobicContact CD1-CB 3.69Å; I497-Q507 HydrophobicContact CD1-CG 3.84Å; I497-Q507 HydrophobicContact CG1-CB 4.39Å; I497-Q507 HydrophobicContact CG1-CG 3.98Å; I497-Q507 HydrophobicContact CG2-CG 3.96Å; I497-I514 HydrophobicContact CD1-CB 4.04Å; I497-I514 HydrophobicContact CD1-CD1 4.2Å; I497-I514 HydrophobicContact CD1-CG2 3.72Å
498A71Confident65.9Low8 Ų872.9 Ų72.97%0.06640%0.395CS..PPolyproline II helixtrans-54.5141.1171.200000110T340 I341 D342 T500 A503T340-A498 HydrophobicContact CG2-CB 3.98Å; I341-A498 PolarHBondContact O-N 2.04Å; I341-A498 VanDerWaalsContact O-N 3.14Å; D342-A498 HydrophobicContact CB-CB 3.89Å; D342-A498 VanDerWaalsContact OD1-CB 3.23Å; D342-A498 WeakPolarHBondContact OD1-CB 3.16Å; A498-T500 PolarHBondContact O-N 2.64Å; A498-A503 HydrophobicContact CB-CB 4.06Å
499A72.4Confident68.3Low97 Ų9772.9 Ų72.980%0.80239%0.39SS*.SBendtrans-78.249.2-178.400000111.7I497I497-A499 PolarHBondContact O-N 3.3Å
500T77.9Confident70.5Confident57 Ų5771.8 Ų71.835%0.3538%0.376SS..SBendtrans-116.4142.9176.864.40000109.2A498 Q502 A503 M504A498-T500 PolarHBondContact O-N 2.64Å; T500-Q502 VanDerWaalsContact C-N 3.26Å; T500-Q502 PolarHBondContact O-N 3.29Å; T500-A503 PolarHBondContact O-N 3.1Å; T500-A503 WeakPolarHBondContact OG1-CB 3.35Å; T500-A503 PolarHBondContact OG1-N 3.08Å; T500-M504 WeakPolarHBondContact O-CG 3.44Å; T500-M504 PolarHBondContact O-N 3.16Å; T500-M504 VanDerWaalsContact O-N 3.13Å
501E83Confident72.5Confident91 Ų9171.7 Ų71.743%0.42538%0.377SS..Hα-helixtrans-52.5-47179.3-173.8-172.5159.100110.8A503 M504 M505 K557 W559E501-A503 PolarHBondContact O-N 2.78Å; E501-M504 PolarHBondContact O-N 3.42Å; E501-M505 HydrophobicContact CG-CG 4.37Å; E501-M505 HydrophobicContact CG-SD 3.8Å; E501-M505 VanDerWaalsContact O-CG 3.24Å; E501-M505 WeakPolarHBondContact O-CG 3.37Å; E501-M505 PolarHBondContact O-N 3.22Å; E501-K557 WeakPolarHBondContact OE1-CD 3.46Å; E501-K557 IonicContact OE1-NZ 3.04Å; E501-K557 PolarHBondContact OE1-NZ 2.73Å; E501-K557 IonicContact OE2-NZ 3.04Å; E501-K557 PolarHBondContact OE2-NZ 3.28Å; E501-W559 HydrophobicContact CG-CZ2 4.18Å
502Q82.3Confident74.4Confident129 Ų12969 Ų6960%0.60335%0.349SS*.Hα-helixtrans-62-44.6-179.1-70.3-175-1900113.4T500 M505 K506T500-Q502 VanDerWaalsContact C-N 3.26Å; T500-Q502 PolarHBondContact O-N 3.29Å; Q502-M505 PolarHBondContact O-N 3.13Å; Q502-K506 VanDerWaalsContact O-CB 3.31Å; Q502-K506 WeakPolarHBondContact O-CB 3.33Å; Q502-K506 PolarHBondContact O-N 3.42Å
503A80.4Confident76.2Confident11 Ų1160.8 Ų60.89%0.09132%0.318CS..Hα-helixtrans-65.3-41.6179.300000111.2I497 A498 T500 E501 Q507I497-A503 HydrophobicContact CG2-CB 3.85Å; A498-A503 HydrophobicContact CB-CB 4.06Å; T500-A503 PolarHBondContact O-N 3.1Å; T500-A503 WeakPolarHBondContact OG1-CB 3.35Å; T500-A503 PolarHBondContact OG1-N 3.08Å; E501-A503 PolarHBondContact O-N 2.78Å; A503-Q507 WeakPolarHBondContact O-CB 3.14Å; A503-Q507 VanDerWaalsContact O-CG 3.25Å; A503-Q507 WeakPolarHBondContact O-CG 3.44Å; A503-Q507 PolarHBondContact O-N 2.04Å
504M85.9Confident77.6Confident36 Ų3654.7 Ų54.718%0.17730%0.296CS..Hα-helixtrans-63.9-47.8176.7-7017862.100112.1I497 T500 E501 K506 Q507 L508 I514 A516 W559I497-M504 HydrophobicContact CG2-CG 4.24Å; T500-M504 WeakPolarHBondContact O-CG 3.44Å; T500-M504 PolarHBondContact O-N 3.16Å; T500-M504 VanDerWaalsContact O-N 3.13Å; E501-M504 PolarHBondContact O-N 3.42Å; M504-K506 PolarHBondContact O-N 3.13Å; M504-Q507 PolarHBondContact O-N 3.25Å; M504-L508 VanDerWaalsContact O-CB 3.28Å; M504-L508 WeakPolarHBondContact O-CB 3.46Å; M504-L508 PolarHBondContact O-N 2.98Å; M504-I514 HydrophobicContact CB-CD1 3.84Å; M504-I514 HydrophobicContact CE-CD1 4.07Å; M504-I514 HydrophobicContact CG-CD1 4.12Å; M504-A516 HydrophobicContact CE-CB 4.07Å; M504-W559 HydrophobicContact CB-CH2 3.68Å; M504-W559 HydrophobicContact CB-CZ2 4.19Å; M504-W559 HydrophobicContact CB-CZ3 4.5Å; M504-W559 HydrophobicContact CE-CH2 4.32Å; M504-W559 HydrophobicContact CE-CZ2 4.1Å; M504-W559 HydrophobicContact SD-CZ2 4.44Å
505M86.5Confident78.8Confident22 Ų2255 Ų5511%0.10829%0.285CS..Hα-helixtrans-61.3-44.7177.7-67.4170.68500111.4L349 E501 Q502 L508 Y509 W550 W559L349-M505 HydrophobicContact CB-CE 4.34Å; L349-M505 HydrophobicContact CD1-CB 3.61Å; L349-M505 HydrophobicContact CD1-CE 4.35Å; L349-M505 HydrophobicContact CD1-SD 4.28Å; E501-M505 HydrophobicContact CG-CG 4.37Å; E501-M505 HydrophobicContact CG-SD 3.8Å; E501-M505 VanDerWaalsContact O-CG 3.24Å; E501-M505 WeakPolarHBondContact O-CG 3.37Å; E501-M505 PolarHBondContact O-N 3.22Å; Q502-M505 PolarHBondContact O-N 3.13Å; M505-L508 PolarHBondContact O-N 3.18Å; M505-Y509 VanDerWaalsContact O-CB 3.26Å; M505-Y509 WeakPolarHBondContact O-CB 3.01Å; M505-Y509 PolarHBondContact O-N 3.14Å; M505-W550 HydrophobicContact CB-CE3 4.32Å; M505-W550 HydrophobicContact CB-CH2 4.19Å; M505-W550 HydrophobicContact CB-CZ2 4.42Å; M505-W550 HydrophobicContact CB-CZ3 4.13Å; M505-W550 HydrophobicContact CE-CD2 3.85Å; M505-W550 HydrophobicContact CE-CG 4.02Å; M505-W550 HydrophobicContact CE-CZ2 3.85Å; M505-W550 HydrophobicContact CG-CD2 4.13Å; M505-W550 HydrophobicContact CG-CE3 4.16Å; M505-W550 HydrophobicContact CG-CZ3 4.46Å; M505-W559 HydrophobicContact CG-CH2 3.58Å; M505-W559 HydrophobicContact CG-CZ3 4.02Å
506K82.8Confident79.7Confident15 Ų1552.1 Ų52.17%0.06528%0.277CS..Hα-helixtrans-62.3-46.1179.4-179.4174.7171.4-178.70112.1D343 S345 V347 Q502 M504 Y509 Q510D343-K506 PolarHBondContact O-NZ 3.06Å; D343-K506 IonicContact OD1-NZ 3.5Å; D343-K506 IonicContact OD2-NZ 3.46Å; D343-K506 PolarHBondContact OD2-NZ 2.99Å; S345-K506 PolarHBondContact O-NZ 3.25Å; S345-K506 PolarHBondContact OG-NZ 2.9Å; V347-K506 HydrophobicContact CG2-CD 4.21Å; V347-K506 HydrophobicContact CG2-CG 4.45Å; Q502-K506 VanDerWaalsContact O-CB 3.31Å; Q502-K506 WeakPolarHBondContact O-CB 3.33Å; Q502-K506 PolarHBondContact O-N 3.42Å; M504-K506 PolarHBondContact O-N 3.13Å; K506-Y509 PolarHBondContact O-N 2.62Å; K506-Q510 WeakPolarHBondContact O-CB 3.08Å; K506-Q510 WeakPolarHBondContact O-CG 3.31Å; K506-Q510 PolarHBondContact O-N 3.02Å
507Q82.2Confident80.1Confident15 Ų1549.3 Ų49.37%0.0728%0.276CS..Hα-helixtrans-64.4-42.3177.5-70.6-61.9-34.100111.7Y495 I497 A503 M504 N511 I514Y495-Q507 PolarHBondContact OH-OE1 2.58Å; I497-Q507 HydrophobicContact CD1-CB 3.69Å; I497-Q507 HydrophobicContact CD1-CG 3.84Å; I497-Q507 HydrophobicContact CG1-CB 4.39Å; I497-Q507 HydrophobicContact CG1-CG 3.98Å; I497-Q507 HydrophobicContact CG2-CG 3.96Å; A503-Q507 WeakPolarHBondContact O-CB 3.14Å; A503-Q507 VanDerWaalsContact O-CG 3.25Å; A503-Q507 WeakPolarHBondContact O-CG 3.44Å; A503-Q507 PolarHBondContact O-N 2.04Å; M504-Q507 PolarHBondContact O-N 3.25Å; Q507-N511 WeakPolarHBondContact O-CA 3.48Å; Q507-N511 WeakPolarHBondContact O-CB 3.25Å; Q507-N511 PolarHBondContact O-N 3.23Å; Q507-N511 PolarHBondContact OE1-ND2 3.13Å; Q507-I514 HydrophobicContact CB-CG2 4.09Å
508L85.2Confident80.4Confident0 Ų050.7 Ų50.70%028%0.28CS..Hα-helixtrans-63-42.5175.2175.459000112.2F353 W359 M504 M505 G512 I514 I547 W550 W559F353-L508 HydrophobicContact CD1-CD2 4.23Å; F353-L508 HydrophobicContact CD1-CG 4.06Å; F353-L508 HydrophobicContact CE1-CD1 4.19Å; F353-L508 HydrophobicContact CE1-CD2 4.43Å; F353-L508 HydrophobicContact CE1-CG 3.81Å; W359-L508 VanDerWaalsContact CH2-O 3.3Å; W359-L508 WeakPolarHBondContact CH2-O 3.13Å; M504-L508 VanDerWaalsContact O-CB 3.28Å; M504-L508 WeakPolarHBondContact O-CB 3.46Å; M504-L508 PolarHBondContact O-N 2.98Å; M505-L508 PolarHBondContact O-N 3.18Å; L508-G512 WeakPolarHBondContact CA-O 3.49Å; L508-G512 WeakPolarHBondContact CD1-O 3.16Å; L508-G512 WeakPolarHBondContact O-CA 3.47Å; L508-G512 PolarHBondContact O-N 3.11Å; L508-G512 VanDerWaalsContact O-N 3.15Å; L508-I514 HydrophobicContact CB-CG2 4.41Å; L508-I547 HydrophobicContact CD2-CG2 3.92Å; L508-W550 HydrophobicContact CB-CZ3 4.02Å; L508-W550 HydrophobicContact CD2-CE3 3.52Å; L508-W550 HydrophobicContact CD2-CZ3 3.58Å; L508-W550 HydrophobicContact CG-CE3 4.25Å; L508-W550 HydrophobicContact CG-CZ3 3.78Å; L508-W559 HydrophobicContact CD2-CZ3 4.38Å
509Y85.9Confident80.7Confident78 Ų7852.2 Ų52.231%0.30629%0.289SS..Hα-helixtrans-65.4-45.1179.5-170.5-114.3000112.9V347 L349 P350 F353 W359 M505 K506 W550V347-Y509 HydrophobicContact CG1-CD1 4.36Å; V347-Y509 HydrophobicContact CG1-CE1 4.47Å; L349-Y509 HydrophobicContact CD2-CD1 4.01Å; L349-Y509 HydrophobicContact CD2-CG 3.86Å; P350-Y509 HydrophobicContact CG-CD2 4.49Å; P350-Y509 HydrophobicContact CG-CE2 4.15Å; F353-Y509 AromaticContact CD2-CD2 3.66Å; F353-Y509 HydrophobicContact CD2-CD2 3.66Å; F353-Y509 HydrophobicContact CD2-CE2 4.01Å; F353-Y509 AromaticContact CE2-CD2 3.52Å; F353-Y509 HydrophobicContact CE2-CD2 3.52Å; F353-Y509 AromaticContact CE2-CE2 3.92Å; F353-Y509 HydrophobicContact CE2-CE2 3.92Å; F353-Y509 HydrophobicContact CG-CD2 4.39Å; F353-Y509 HydrophobicContact CZ-CD2 4.17Å; W359-Y509 WeakPolarHBondContact CH2-O 3.47Å; W359-Y509 WeakPolarHBondContact CZ2-O 3.44Å; M505-Y509 VanDerWaalsContact O-CB 3.26Å; M505-Y509 WeakPolarHBondContact O-CB 3.01Å; M505-Y509 PolarHBondContact O-N 3.14Å; K506-Y509 PolarHBondContact O-N 2.62Å; Y509-W550 HydrophobicContact CD2-CH2 4.16Å; Y509-W550 HydrophobicContact CG-CH2 4.45Å
510Q82.8Confident80.9Confident95 Ų9547.6 Ų47.644%0.44425%0.251SS..Hα-helixtrans-87.7-35.4-172.5-67-177.3-37.300113.1K506K506-Q510 WeakPolarHBondContact O-CB 3.08Å; K506-Q510 WeakPolarHBondContact O-CG 3.31Å; K506-Q510 PolarHBondContact O-N 3.02Å
511N80.3Confident80.9Confident102 Ų10248.2 Ų48.255%0.54525%0.247SC..Hα-helixtrans-118.3-5.4-167.8-60.4-51.1000113.9Q507Q507-N511 WeakPolarHBondContact O-CA 3.48Å; Q507-N511 WeakPolarHBondContact O-CB 3.25Å; Q507-N511 PolarHBondContact O-N 3.23Å; Q507-N511 PolarHBondContact OE1-ND2 3.13Å
512G81.1Confident80.3Confident6 Ų645 Ų456%0.06223%0.234CC..  trans91.5-169.2179.500000114.2W359 L508 I514W359-G512 VanDerWaalsContact CH2-CA 3.45Å; L508-G512 WeakPolarHBondContact CA-O 3.49Å; L508-G512 WeakPolarHBondContact CD1-O 3.16Å; L508-G512 WeakPolarHBondContact O-CA 3.47Å; L508-G512 PolarHBondContact O-N 3.11Å; L508-G512 VanDerWaalsContact O-N 3.15Å; G512-I514 PolarHBondContact O-N 3.06Å
513P82.3Confident79.8Confident50 Ų5039.4 Ų39.433%0.32521%0.208SC..  trans-50.9133.1-171.3-30.736.7000114.7A355 I366 R546 I547 I548A355-P513 HydrophobicContact CB-CG 4.17Å; I366-P513 HydrophobicContact CG1-CG 4.25Å; I366-P513 HydrophobicContact CG2-CG 4.16Å; P513-R546 HydrophobicContact CB-CG 3.79Å; P513-I547 VanDerWaalsContact CA-O 3.27Å; P513-I547 WeakPolarHBondContact CA-O 3.06Å; P513-I548 HydrophobicContact CB-CG2 4.13Å; P513-I548 HydrophobicContact CG-CG2 4.13Å
514I81.2Confident79.8Confident16 Ų1639.2 Ų39.28%0.08221%0.205CC..EExtended strand (participates in β ladder)trans-108.9158.5179.864.4173.3000111.2I497 M504 Q507 L508 G512 R546 I547I497-I514 HydrophobicContact CD1-CB 4.04Å; I497-I514 HydrophobicContact CD1-CD1 4.2Å; I497-I514 HydrophobicContact CD1-CG2 3.72Å; M504-I514 HydrophobicContact CB-CD1 3.84Å; M504-I514 HydrophobicContact CE-CD1 4.07Å; M504-I514 HydrophobicContact CG-CD1 4.12Å; Q507-I514 HydrophobicContact CB-CG2 4.09Å; L508-I514 HydrophobicContact CB-CG2 4.41Å; G512-I514 PolarHBondContact O-N 3.06Å; I514-R546 CarbonylContact O-C 3.44Å; I514-R546 WeakPolarHBondContact O-CA 3.43Å; I514-I547 HydrophobicContact CG1-CB 3.85Å; I514-I547 HydrophobicContact CG1-CG1 4.3Å; I514-I547 PolarHBondContact N-O 2.89Å; I514-I547 VanDerWaalsContact N-O 3.12Å; I514-I547 PolarHBondContact O-N 3.44Å
515V78.2Confident78.9Confident73 Ų7338 Ų3844%0.44220%0.199SC..EExtended strand (participates in β ladder)trans-96.4124.2171.6-178.70000108.8A544 V545V515-A544 HydrophobicContact CG1-CB 4.13Å; V515-V545 WeakPolarHBondContact CA-O 3Å
516A78.2Confident77.9Confident17 Ų1739.6 Ų39.614%0.1420%0.204CC..EExtended strand (participates in β ladder)trans-114.1145.1172.300000109.7M504 A544 V545 I547M504-A516 HydrophobicContact CE-CB 4.07Å; A516-A544 CarbonylContact O-C 3.42Å; A516-A544 VanDerWaalsContact O-CA 3.3Å; A516-A544 WeakPolarHBondContact O-CA 3.35Å; A516-V545 HydrophobicContact CB-CG2 4.47Å; A516-V545 PolarHBondContact N-O 3.08Å; A516-V545 PolarHBondContact O-N 2.68Å; A516-I547 HydrophobicContact CB-CD1 3.98Å; A516-I547 HydrophobicContact CB-CG1 3.56Å
517T74.3Confident77.2Confident83 Ų8340.7 Ų40.751%0.50921%0.208SC..EExtended strand (participates in β ladder)trans-107.3141.2168.155.30000108.9H543 A544T517-H543 VanDerWaalsContact CA-O 3.29Å; T517-H543 WeakPolarHBondContact CA-O 3.4Å; T517-A544 HydrophobicContact CG2-CB 4.03Å
518F73.7Confident76.1Confident63 Ų6345.2 Ų45.228%0.27623%0.228SC..EExtended strand (participates in β ladder)trans-144156.6178.772.4-68.5000109.9V520 L524 Y542 H543 V545F518-V520 HydrophobicContact CD2-CG2 4.44Å; F518-V520 HydrophobicContact CE1-CG2 4.27Å; F518-V520 HydrophobicContact CE2-CG2 3.81Å; F518-V520 HydrophobicContact CZ-CG2 3.7Å; F518-V520 PolarHBondContact O-N 2.78Å; F518-L524 HydrophobicContact CE2-CD2 3.62Å; F518-L524 HydrophobicContact CZ-CD2 3.68Å; F518-Y542 WeakPolarHBondContact O-CA 3.3Å; F518-H543 VanDerWaalsContact CD1-O 3.28Å; F518-H543 WeakPolarHBondContact CD1-O 3.3Å; F518-H543 HydrophobicContact CE1-CB 4.04Å; F518-H543 HydrophobicContact CZ-CB 4.47Å; F518-H543 PolarHBondContact N-O 2.72Å; F518-H543 PolarHBondContact O-N 3.01Å; F518-V545 HydrophobicContact CD1-CG1 4.37Å; F518-V545 HydrophobicContact CD1-CG2 3.82Å; F518-V545 HydrophobicContact CE1-CB 4.25Å; F518-V545 HydrophobicContact CE1-CG1 3.51Å; F518-V545 HydrophobicContact CE1-CG2 3.8Å; F518-V545 HydrophobicContact CZ-CG1 4.22Å
519T77.3Confident75.3Confident40 Ų4049.2 Ų49.225%0.24526%0.256CS..EExtended strand (participates in β ladder)trans-71.4123.1173.6-53.40000109.1Y521 N539 Y542T519-Y521 HydrophobicContact CG2-CD2 4.24Å; T519-Y521 HydrophobicContact CG2-CE1 4.28Å; T519-Y521 HydrophobicContact CG2-CE2 3.71Å; T519-N539 HydrophobicContact CG2-CB 4.08Å; T519-N539 VanDerWaalsContact CG2-ND2 3.34Å; T519-N539 WeakPolarHBondContact CG2-ND2 3.24Å; T519-Y542 WeakPolarHBondContact OG1-CE1 3.44Å
520V77.3Confident74.8Confident0 Ų047.2 Ų47.20%026%0.259CS..EExtended strand (participates in β ladder)trans-90123.5173.6172.40000108.9L324 F518 L524 Y525 A540 G541 H543L324-V520 HydrophobicContact CD1-CB 3.84Å; L324-V520 HydrophobicContact CD1-CG1 3.91Å; L324-V520 HydrophobicContact CD1-CG2 4.44Å; L324-V520 HydrophobicContact CD2-CB 4.29Å; L324-V520 HydrophobicContact CD2-CG1 4.1Å; L324-V520 HydrophobicContact CD2-CG2 4.14Å; F518-V520 HydrophobicContact CD2-CG2 4.44Å; F518-V520 HydrophobicContact CE1-CG2 4.27Å; F518-V520 HydrophobicContact CE2-CG2 3.81Å; F518-V520 HydrophobicContact CZ-CG2 3.7Å; F518-V520 PolarHBondContact O-N 2.78Å; V520-L524 HydrophobicContact CB-CD2 4.45Å; V520-L524 HydrophobicContact CG1-CB 4.39Å; V520-L524 HydrophobicContact CG1-CD2 3.92Å; V520-L524 HydrophobicContact CG2-CD2 3.99Å; V520-Y525 HydrophobicContact CG1-CE1 3.89Å; V520-A540 PolarHBondContact O-N 3.05Å; V520-G541 PolarHBondContact N-O 3.29Å; V520-H543 HydrophobicContact CG2-CB 3.32Å
521Y77.2Confident74.7Confident71 Ų7146 Ų4628%0.27826%0.255SS..EExtended strand (participates in β ladder)trans-101.5154170.6-64.2-89.2000110.2T519 D523 L524 H534 I538 N539T519-Y521 HydrophobicContact CG2-CD2 4.24Å; T519-Y521 HydrophobicContact CG2-CE1 4.28Å; T519-Y521 HydrophobicContact CG2-CE2 3.71Å; Y521-D523 WeakPolarHBondContact CB-OD1 3.48Å; Y521-D523 PolarHBondContact O-N 3.44Å; Y521-D523 VanDerWaalsContact O-N 3.14Å; Y521-L524 VanDerWaalsContact O-CB 3.28Å; Y521-L524 WeakPolarHBondContact O-CB 3.31Å; Y521-L524 PolarHBondContact O-N 2.75Å; Y521-H534 VanDerWaalsContact CB-CE1 3.45Å; Y521-H534 WeakPolarHBondContact CB-CE1 3.02Å; Y521-H534 WeakPolarHBondContact CB-ND1 3.17Å; Y521-H534 AromaticContact CD1-CE1 3.33Å; Y521-H534 WeakPolarHBondContact CD1-CE1 3.29Å; Y521-H534 AromaticContact CD1-ND1 3.84Å; Y521-H534 AromaticContact CD1-NE2 3.52Å; Y521-H534 HydrophobicContact CD2-CB 3.91Å; Y521-H534 AromaticContact CD2-CD2 3.73Å; Y521-H534 AromaticContact CD2-CE1 3.89Å; Y521-H534 AromaticContact CD2-CG 3.43Å; Y521-H534 VanDerWaalsContact CD2-CG 3.43Å; Y521-H534 AromaticContact CD2-ND1 3.58Å; Y521-H534 AromaticContact CE1-CE1 3.98Å; Y521-H534 AromaticContact CE1-NE2 3.67Å; Y521-H534 HydrophobicContact CE2-CB 4.35Å; Y521-H534 AromaticContact CE2-CD2 3.74Å; Y521-H534 AromaticContact CE2-CG 3.88Å; Y521-H534 HydrophobicContact CG-CB 4.49Å; Y521-H534 AromaticContact CG-CD2 3.9Å; Y521-H534 AromaticContact CG-CE1 3.27Å; Y521-H534 AromaticContact CG-CG 3.63Å; Y521-H534 AromaticContact CG-ND1 3.26Å; Y521-H534 VanDerWaalsContact CG-ND1 3.26Å; Y521-H534 AromaticContact CG-NE2 3.7Å; Y521-H534 AromaticContact CZ-CD2 3.94Å; Y521-H534 AromaticContact CZ-NE2 3.96Å; Y521-I538 CarbonylContact C-O 3.56Å; Y521-I538 VanDerWaalsContact CA-O 3.22Å; Y521-I538 WeakPolarHBondContact CA-O 3.16Å; Y521-N539 HydrophobicContact CD1-CB 4.23Å; Y521-N539 HydrophobicContact CE1-CB 4.02Å
522T70.4Confident74.7Confident23 Ų2344.3 Ų44.314%0.14124%0.241CC..G310 helixtrans-65.8-16.7-174.757.20000114.4L524 Y525 Y526 G537 I538 A540T522-L524 VanDerWaalsContact C-N 3.32Å; T522-Y525 HydrophobicContact CG2-CD2 4.18Å; T522-Y525 HydrophobicContact CG2-CE2 3.53Å; T522-Y525 WeakPolarHBondContact O-CB 3.2Å; T522-Y525 WeakPolarHBondContact O-CD2 3.23Å; T522-Y525 PolarHBondContact O-N 2.74Å; T522-Y526 WeakPolarHBondContact O-CD2 3.42Å; T522-Y526 WeakPolarHBondContact O-CE2 3.35Å; T522-G537 WeakPolarHBondContact OG1-CA 3.23Å; T522-I538 HydrophobicContact CG2-CD1 3.72Å; T522-I538 HydrophobicContact CG2-CG1 3.22Å; T522-I538 PolarHBondContact N-O 3.39Å; T522-I538 PolarHBondContact OG1-N 3.34Å; T522-I538 VanDerWaalsContact OG1-N 3.15Å; T522-A540 HydrophobicContact CG2-CB 4.1Å
523D72.1Confident74.7Confident12 Ų1248.9 Ų48.96%0.06426%0.261CS..G310 helixtrans-67.5-29.5171.356.9-14.6000113Y521 Y525 Y526 Y532 H534 K535 K536Y521-D523 WeakPolarHBondContact CB-OD1 3.48Å; Y521-D523 PolarHBondContact O-N 3.44Å; Y521-D523 VanDerWaalsContact O-N 3.14Å; D523-Y525 PolarHBondContact O-N 2.81Å; D523-Y525 VanDerWaalsContact O-N 3.11Å; D523-Y526 WeakPolarHBondContact O-CB 3.37Å; D523-Y526 PolarHBondContact O-N 3.25Å; D523-Y532 PolarHBondContact OD1-OH 3.05Å; D523-H534 IonicContact OD1-CE1 2.64Å; D523-H534 IonicContact OD1-ND1 3.88Å; D523-H534 PolarHBondContact OD1-ND1 3.21Å; D523-H534 VanDerWaalsContact OD1-ND1 3.1Å; D523-H534 WeakPolarHBondContact OD2-CA 3.37Å; D523-H534 IonicContact OD2-CE1 3.47Å; D523-H534 IonicContact OD2-CG 3.31Å; D523-H534 IonicContact OD2-ND1 2.73Å; D523-H534 PolarHBondContact OD2-ND1 2.79Å; D523-K535 PolarHBondContact OD2-N 3.07Å; D523-K536 WeakPolarHBondContact CB-O 3.36Å; D523-K536 PolarHBondContact OD2-N 3.26Å
524L80.1Confident74.4Confident6 Ų649.7 Ų49.73%0.03126%0.26CS..G310 helixtrans-57.3-26.5174.1-173.663.1000112.7F518 V520 Y521 T522 Y526 Y527 Y532 W565 W569F518-L524 HydrophobicContact CE2-CD2 3.62Å; F518-L524 HydrophobicContact CZ-CD2 3.68Å; V520-L524 HydrophobicContact CB-CD2 4.45Å; V520-L524 HydrophobicContact CG1-CB 4.39Å; V520-L524 HydrophobicContact CG1-CD2 3.92Å; V520-L524 HydrophobicContact CG2-CD2 3.99Å; Y521-L524 VanDerWaalsContact O-CB 3.28Å; Y521-L524 WeakPolarHBondContact O-CB 3.31Å; Y521-L524 PolarHBondContact O-N 2.75Å; T522-L524 VanDerWaalsContact C-N 3.32Å; L524-Y526 PolarHBondContact O-N 3.11Å; L524-Y527 HydrophobicContact CD1-CG 4.4Å; L524-Y527 WeakPolarHBondContact O-CB 3.5Å; L524-Y527 PolarHBondContact O-N 2.82Å; L524-Y527 VanDerWaalsContact O-N 3.12Å; L524-Y532 HydrophobicContact CB-CE1 4.49Å; L524-Y532 HydrophobicContact CB-CE2 3.79Å; L524-Y532 HydrophobicContact CD1-CD1 3.78Å; L524-Y532 HydrophobicContact CD1-CD2 3.57Å; L524-Y532 HydrophobicContact CD1-CE1 3.81Å; L524-Y532 HydrophobicContact CD1-CE2 3.59Å; L524-Y532 HydrophobicContact CD1-CG 3.65Å; L524-Y532 HydrophobicContact CG-CE2 4.29Å; L524-W565 HydrophobicContact CD2-CH2 3.93Å; L524-W565 HydrophobicContact CD2-CZ3 4.4Å; L524-W565 HydrophobicContact CG-CH2 4.36Å; L524-W565 HydrophobicContact CG-CZ3 4.42Å; L524-W569 HydrophobicContact CD1-CH2 4.12Å; L524-W569 HydrophobicContact CD1-CZ2 3.81Å; L524-W569 HydrophobicContact CG-CZ2 3.95Å
525Y68.1Low73.8Confident10 Ų1054.6 Ų54.64%0.03928%0.281CS..G310 helixtrans-64.9-23.1174.9-52.9-31.5000113.3N309 F312 M320 V520 T522 D523 A540N309-Y525 WeakPolarHBondContact CB-O 3.07Å; N309-Y525 PolarHBondContact N-O 2.65Å; F312-Y525 AromaticContact CD1-CD1 3.88Å; F312-Y525 HydrophobicContact CD1-CD1 3.88Å; F312-Y525 HydrophobicContact CD1-CE1 4.12Å; F312-Y525 HydrophobicContact CD1-CG 4.3Å; F312-Y525 AromaticContact CD2-CD1 3.88Å; F312-Y525 HydrophobicContact CD2-CD1 3.88Å; F312-Y525 AromaticContact CD2-CG 3.96Å; F312-Y525 HydrophobicContact CD2-CG 3.96Å; F312-Y525 AromaticContact CE1-CD1 3.81Å; F312-Y525 HydrophobicContact CE1-CD1 3.81Å; F312-Y525 AromaticContact CE1-CE1 3.96Å; F312-Y525 HydrophobicContact CE1-CE1 3.96Å; F312-Y525 AromaticContact CE2-CD1 3.79Å; F312-Y525 HydrophobicContact CE2-CD1 3.79Å; F312-Y525 HydrophobicContact CE2-CG 4.3Å; F312-Y525 AromaticContact CG-CD1 3.96Å; F312-Y525 HydrophobicContact CG-CD1 3.96Å; F312-Y525 AromaticContact CG-CG 3.99Å; F312-Y525 HydrophobicContact CG-CG 3.99Å; F312-Y525 AromaticContact CZ-CD1 3.78Å; F312-Y525 HydrophobicContact CZ-CD1 3.78Å; F312-Y525 HydrophobicContact CZ-CE1 4.27Å; M320-Y525 HydrophobicContact CE-CE2 4.48Å; M320-Y525 HydrophobicContact SD-CD2 4.05Å; M320-Y525 HydrophobicContact SD-CE2 3.26Å; M320-Y525 WeakPolarHBondContact SD-CE2 3.16Å; V520-Y525 HydrophobicContact CG1-CE1 3.89Å; T522-Y525 HydrophobicContact CG2-CD2 4.18Å; T522-Y525 HydrophobicContact CG2-CE2 3.53Å; T522-Y525 WeakPolarHBondContact O-CB 3.2Å; T522-Y525 WeakPolarHBondContact O-CD2 3.23Å; T522-Y525 PolarHBondContact O-N 2.74Å; D523-Y525 PolarHBondContact O-N 2.81Å; D523-Y525 VanDerWaalsContact O-N 3.11Å; Y525-A540 HydrophobicContact CE2-CB 4.5Å; Y525-A540 WeakPolarHBondContact OH-CB 3.46Å
526Y64.4Low72.6Confident57 Ų5755.2 Ų55.222%0.22428%0.278CS..G310 helixtrans-95-5179.1-55.2-98000111.9L306 G307 I308 T522 D523 L524 K528L306-Y526 HydrophobicContact CB-CD1 4.33Å; L306-Y526 HydrophobicContact CD2-CD1 4.11Å; L306-Y526 HydrophobicContact CD2-CD2 4.36Å; L306-Y526 HydrophobicContact CD2-CG 3.77Å; G307-Y526 WeakPolarHBondContact O-CA 3.18Å; G307-Y526 WeakPolarHBondContact O-CD1 3.46Å; I308-Y526 HydrophobicContact CB-CE1 4.29Å; I308-Y526 HydrophobicContact CG1-CD1 4.16Å; I308-Y526 HydrophobicContact CG1-CE1 3.44Å; I308-Y526 VanDerWaalsContact CG1-CE1 3.44Å; T522-Y526 WeakPolarHBondContact O-CD2 3.42Å; T522-Y526 WeakPolarHBondContact O-CE2 3.35Å; D523-Y526 WeakPolarHBondContact O-CB 3.37Å; D523-Y526 PolarHBondContact O-N 3.25Å; L524-Y526 PolarHBondContact O-N 3.11Å; Y526-K528 PolarHBondContact O-N 3.42Å
527Y69.4Low71.5Confident37 Ų3755.5 Ų55.515%0.14528%0.282CS..  trans-60.9130.4176.7176.9-103.7000110.8L524 S529 G530 Y532 W569L524-Y527 HydrophobicContact CD1-CG 4.4Å; L524-Y527 WeakPolarHBondContact O-CB 3.5Å; L524-Y527 PolarHBondContact O-N 2.82Å; L524-Y527 VanDerWaalsContact O-N 3.12Å; Y527-S529 WeakPolarHBondContact CE2-O 3.09Å; Y527-G530 WeakPolarHBondContact CE2-O 3.22Å; Y527-G530 VanDerWaalsContact CZ-O 3.27Å; Y527-G530 PolarHBondContact OH-O 3.36Å; Y527-Y532 HydrophobicContact CD2-CD2 4.06Å; Y527-Y532 HydrophobicContact CD2-CG 4.31Å; Y527-Y532 HydrophobicContact CG-CD2 4.34Å; Y527-W569 AromaticContact CD1-CH2 3.74Å; Y527-W569 HydrophobicContact CD1-CH2 3.74Å; Y527-W569 AromaticContact CD1-CZ2 3.63Å; Y527-W569 HydrophobicContact CD1-CZ2 3.63Å; Y527-W569 HydrophobicContact CD1-CZ3 4.41Å; Y527-W569 HydrophobicContact CE1-CH2 4.23Å; Y527-W569 HydrophobicContact CG-CZ2 4.35Å
528K58.1Low70.8Confident110 Ų11052.5 Ų52.548%0.47826%0.263SS..  trans-120.8-45.6177-75.8-168.3173.2-168.40112.6Y526 G570 E571Y526-K528 PolarHBondContact O-N 3.42Å; K528-G570 CarbonylContact O-C 3.33Å; K528-G570 WeakPolarHBondContact O-CA 3.46Å; K528-E571 PolarHBondContact O-N 3.16Å
529S69.6Low70.6Confident84 Ų8450.6 Ų50.659%0.58726%0.255SS*.SBendtrans-165.2166.8-178.256.90000111.6Y527Y527-S529 WeakPolarHBondContact CE2-O 3.09Å
530G75.5Confident70Confident36 Ų3648.7 Ų48.737%0.37124%0.244SC..SBendtrans88.2-171-179.800000112.6Y527 Y532 E571Y527-G530 WeakPolarHBondContact CE2-O 3.22Å; Y527-G530 VanDerWaalsContact CZ-O 3.27Å; Y527-G530 PolarHBondContact OH-O 3.36Å; G530-Y532 PolarHBondContact O-N 3.33Å; G530-E571 PolarHBondContact N-OE1 3.07Å
531I80.7Confident69.5Low71 Ų7149.3 Ų49.336%0.36425%0.251SS..  trans-74.7117.2175.5-59.8172.5000108.9E533 E553 E556 Y558I531-E533 PolarHBondContact O-N 3.43Å; I531-E553 HydrophobicContact CD1-CB 3.87Å; I531-E556 HydrophobicContact CD1-CB 4.43Å; I531-Y558 HydrophobicContact CD1-CD1 3.5Å; I531-Y558 VanDerWaalsContact CD1-CD1 3.5Å; I531-Y558 HydrophobicContact CD1-CE1 4.24Å; I531-Y558 HydrophobicContact CD1-CG 4.08Å; I531-Y558 HydrophobicContact CG1-CD1 3.95Å; I531-Y558 HydrophobicContact CG1-CG 4.08Å
532Y80.6Confident69.1Low65 Ų6548.8 Ų48.826%0.25525%0.249SC..  trans-77.1122171.8171.7-99.2000109.9D523 L524 Y527 G530 H534D523-Y532 PolarHBondContact OD1-OH 3.05Å; L524-Y532 HydrophobicContact CB-CE1 4.49Å; L524-Y532 HydrophobicContact CB-CE2 3.79Å; L524-Y532 HydrophobicContact CD1-CD1 3.78Å; L524-Y532 HydrophobicContact CD1-CD2 3.57Å; L524-Y532 HydrophobicContact CD1-CE1 3.81Å; L524-Y532 HydrophobicContact CD1-CE2 3.59Å; L524-Y532 HydrophobicContact CD1-CG 3.65Å; L524-Y532 HydrophobicContact CG-CE2 4.29Å; Y527-Y532 HydrophobicContact CD2-CD2 4.06Å; Y527-Y532 HydrophobicContact CD2-CG 4.31Å; Y527-Y532 HydrophobicContact CG-CD2 4.34Å; G530-Y532 PolarHBondContact O-N 3.33Å; Y532-H534 HydrophobicContact CE1-CB 4.37Å
533E80.2Confident69.4Low102 Ų10247.7 Ų47.748%0.47724%0.242SC..  trans-123.2130.3164.4-165.8-168.8152.400108I531 K535I531-E533 PolarHBondContact O-N 3.43Å; E533-K535 PolarHBondContact O-N 2.82Å; E533-K535 VanDerWaalsContact O-N 3.16Å; E533-K535 WeakPolarHBondContact OE1-CE 3.34Å; E533-K535 IonicContact OE1-NZ 2.98Å; E533-K535 PolarHBondContact OE1-NZ 3.18Å; E533-K535 WeakPolarHBondContact OE2-CE 3.33Å; E533-K535 IonicContact OE2-NZ 3.11Å; E533-K535 PolarHBondContact OE2-NZ 2.7Å
534H74.9Confident69.3Low68 Ų6847.4 Ų47.432%0.31524%0.241SC..  trans-62.9120.5172169.758000109.2Y521 D523 Y532 K536Y521-H534 VanDerWaalsContact CB-CE1 3.45Å; Y521-H534 WeakPolarHBondContact CB-CE1 3.02Å; Y521-H534 WeakPolarHBondContact CB-ND1 3.17Å; Y521-H534 AromaticContact CD1-CE1 3.33Å; Y521-H534 WeakPolarHBondContact CD1-CE1 3.29Å; Y521-H534 AromaticContact CD1-ND1 3.84Å; Y521-H534 AromaticContact CD1-NE2 3.52Å; Y521-H534 HydrophobicContact CD2-CB 3.91Å; Y521-H534 AromaticContact CD2-CD2 3.73Å; Y521-H534 AromaticContact CD2-CE1 3.89Å; Y521-H534 AromaticContact CD2-CG 3.43Å; Y521-H534 VanDerWaalsContact CD2-CG 3.43Å; Y521-H534 AromaticContact CD2-ND1 3.58Å; Y521-H534 AromaticContact CE1-CE1 3.98Å; Y521-H534 AromaticContact CE1-NE2 3.67Å; Y521-H534 HydrophobicContact CE2-CB 4.35Å; Y521-H534 AromaticContact CE2-CD2 3.74Å; Y521-H534 AromaticContact CE2-CG 3.88Å; Y521-H534 HydrophobicContact CG-CB 4.49Å; Y521-H534 AromaticContact CG-CD2 3.9Å; Y521-H534 AromaticContact CG-CE1 3.27Å; Y521-H534 AromaticContact CG-CG 3.63Å; Y521-H534 AromaticContact CG-ND1 3.26Å; Y521-H534 VanDerWaalsContact CG-ND1 3.26Å; Y521-H534 AromaticContact CG-NE2 3.7Å; Y521-H534 AromaticContact CZ-CD2 3.94Å; Y521-H534 AromaticContact CZ-NE2 3.96Å; D523-H534 IonicContact OD1-CE1 2.64Å; D523-H534 IonicContact OD1-ND1 3.88Å; D523-H534 PolarHBondContact OD1-ND1 3.21Å; D523-H534 VanDerWaalsContact OD1-ND1 3.1Å; D523-H534 WeakPolarHBondContact OD2-CA 3.37Å; D523-H534 IonicContact OD2-CE1 3.47Å; D523-H534 IonicContact OD2-CG 3.31Å; D523-H534 IonicContact OD2-ND1 2.73Å; D523-H534 PolarHBondContact OD2-ND1 2.79Å; Y532-H534 HydrophobicContact CE1-CB 4.37Å; H534-K536 VanDerWaalsContact CE1-C 3.44Å; H534-K536 PolarHBondContact CE1-O 2.92Å; H534-K536 PolarHBondContact ND1-O 3.02Å
535K69.4Low69.3Low119 Ų11947.6 Ų47.652%0.51724%0.242SC..  trans-119.9-28174.5-62.6-65-168.5-172.90111.9D523 E533D523-K535 PolarHBondContact OD2-N 3.07Å; E533-K535 PolarHBondContact O-N 2.82Å; E533-K535 VanDerWaalsContact O-N 3.16Å; E533-K535 WeakPolarHBondContact OE1-CE 3.34Å; E533-K535 IonicContact OE1-NZ 2.98Å; E533-K535 PolarHBondContact OE1-NZ 3.18Å; E533-K535 WeakPolarHBondContact OE2-CE 3.33Å; E533-K535 IonicContact OE2-NZ 3.11Å; E533-K535 PolarHBondContact OE2-NZ 2.7Å
536K52.8Low69.9Low86 Ų8648.6 Ų48.637%0.37425%0.246SC..SBendtrans-149.5162.4-168.9-72.9178.9174.6155.20112.9D523 H534D523-K536 WeakPolarHBondContact CB-O 3.36Å; D523-K536 PolarHBondContact OD2-N 3.26Å; H534-K536 VanDerWaalsContact CE1-C 3.44Å; H534-K536 PolarHBondContact CE1-O 2.92Å; H534-K536 PolarHBondContact ND1-O 3.02Å
537G55.4Low71Confident23 Ų2346.2 Ų46.224%0.23724%0.237CC..SBendtrans93.2167.2174.800000113.8T522T522-G537 WeakPolarHBondContact OG1-CA 3.23Å
538I58.7Low71.8Confident20 Ų2045 Ų4510%0.10323%0.233CC..  trans-91.2153.5-172.454.7-169.7000110.7Y87 T236 L317 Y521 T522 A540Y87-I538 HydrophobicContact CD1-CB 3.58Å; Y87-I538 HydrophobicContact CD1-CD1 3.17Å; Y87-I538 HydrophobicContact CD1-CG1 3.72Å; Y87-I538 HydrophobicContact CD1-CG2 3.68Å; Y87-I538 HydrophobicContact CE1-CB 4.35Å; Y87-I538 HydrophobicContact CE1-CD1 3.08Å; Y87-I538 HydrophobicContact CE1-CG1 4.13Å; Y87-I538 HydrophobicContact CE1-CG2 4.24Å; Y87-I538 HydrophobicContact CG-CB 4.29Å; Y87-I538 HydrophobicContact CG-CD1 4.48Å; Y87-I538 HydrophobicContact CG-CG2 4.2Å; T236-I538 VanDerWaalsContact CB-CG2 3.48Å; T236-I538 HydrophobicContact CG2-CG2 3.79Å; L317-I538 HydrophobicContact CD1-CD1 3.88Å; L317-I538 HydrophobicContact CD2-CD1 4.24Å; Y521-I538 CarbonylContact C-O 3.56Å; Y521-I538 VanDerWaalsContact CA-O 3.22Å; Y521-I538 WeakPolarHBondContact CA-O 3.16Å; T522-I538 HydrophobicContact CG2-CD1 3.72Å; T522-I538 HydrophobicContact CG2-CG1 3.22Å; T522-I538 PolarHBondContact N-O 3.39Å; T522-I538 PolarHBondContact OG1-N 3.34Å; T522-I538 VanDerWaalsContact OG1-N 3.15Å; I538-A540 PolarHBondContact O-N 3.27Å; I538-A540 VanDerWaalsContact O-N 3.16Å
539N71.2Confident73.4Confident22 Ų2239.8 Ų39.812%0.11821%0.21CC..EExtended strand (participates in β ladder)trans-65.3115.8169.1174.7-9000108.2Y87 T519 Y521 G541Y87-N539 CarbonylContact C-O 3.46Å; Y87-N539 WeakPolarHBondContact O-CB 3.48Å; T519-N539 HydrophobicContact CG2-CB 4.08Å; T519-N539 VanDerWaalsContact CG2-ND2 3.34Å; T519-N539 WeakPolarHBondContact CG2-ND2 3.24Å; Y521-N539 HydrophobicContact CD1-CB 4.23Å; Y521-N539 HydrophobicContact CE1-CB 4.02Å; N539-G541 WeakPolarHBondContact OD1-CA 3.41Å; N539-G541 PolarHBondContact OD1-N 3.02Å; N539-G541 PolarHBondContact OD1-O 3.33Å
540A64.4Low74.6Confident0 Ų036.3 Ų36.30%018%0.184CC..EExtended strand (participates in β ladder)trans-94.1-8.717900000112.9L317 K321 L324 V520 T522 Y525 I538L317-A540 HydrophobicContact CD1-CB 4.39Å; K321-A540 WeakPolarHBondContact CG-O 3.45Å; L324-A540 HydrophobicContact CD1-CB 3.83Å; L324-A540 WeakPolarHBondContact CD1-O 3.36Å; V520-A540 PolarHBondContact O-N 3.05Å; T522-A540 HydrophobicContact CG2-CB 4.1Å; Y525-A540 HydrophobicContact CE2-CB 4.5Å; Y525-A540 WeakPolarHBondContact OH-CB 3.46Å; I538-A540 PolarHBondContact O-N 3.27Å; I538-A540 VanDerWaalsContact O-N 3.16Å
541G66.4Low75.3Confident14 Ų1434.7 Ų34.714%0.14417%0.168CC..EExtended strand (participates in β ladder)trans139.9-169-177.500000111.6V520 N539V520-G541 PolarHBondContact N-O 3.29Å; N539-G541 WeakPolarHBondContact OD1-CA 3.41Å; N539-G541 PolarHBondContact OD1-N 3.02Å; N539-G541 PolarHBondContact OD1-O 3.33Å
542Y69.5Low75.4Confident60 Ų6035 Ų3524%0.23517%0.167CC..EExtended strand (participates in β ladder)trans-105.8148.4175.1-60.4-88.5000109L324 V326 K328 F518 T519L324-Y542 VanDerWaalsContact O-O 3.12Å; V326-Y542 WeakPolarHBondContact CB-O 3.01Å; K328-Y542 HydrophobicContact CB-CD2 4.41Å; K328-Y542 HydrophobicContact CB-CE2 3.8Å; K328-Y542 HydrophobicContact CD-CE2 4.38Å; K328-Y542 HydrophobicContact CG-CE2 4.25Å; F518-Y542 WeakPolarHBondContact O-CA 3.3Å; T519-Y542 WeakPolarHBondContact OG1-CE1 3.44Å
543H76.5Confident75.4Confident0 Ų037.5 Ų37.50%018%0.18CC..EExtended strand (participates in β ladder)trans-137.1148.4174.6-16655.4000111.2L324 Q372 T517 F518 V520 N563 W565L324-H543 HydrophobicContact CD2-CB 4.16Å; L324-H543 PolarHBondContact O-ND1 3.23Å; Q372-H543 PolarHBondContact OE1-CE1 3.44Å; T517-H543 VanDerWaalsContact CA-O 3.29Å; T517-H543 WeakPolarHBondContact CA-O 3.4Å; F518-H543 VanDerWaalsContact CD1-O 3.28Å; F518-H543 WeakPolarHBondContact CD1-O 3.3Å; F518-H543 HydrophobicContact CE1-CB 4.04Å; F518-H543 HydrophobicContact CZ-CB 4.47Å; F518-H543 PolarHBondContact N-O 2.72Å; F518-H543 PolarHBondContact O-N 3.01Å; V520-H543 HydrophobicContact CG2-CB 3.32Å; H543-N563 PolarHBondContact CD2-OD1 2.97Å; H543-N563 PolarHBondContact NE2-OD1 3.05Å; H543-W565 AromaticContact CD2-CZ2 3.83Å; H543-W565 AromaticContact CD2-NE1 3.89Å; H543-W565 AromaticContact CE1-NE1 3.45Å; H543-W565 PolarHBondContact CE1-NE1 3.14Å; H543-W565 AromaticContact NE2-CE2 3.75Å; H543-W565 AromaticContact NE2-NE1 3.15Å; H543-W565 PolarHBondContact NE2-NE1 3.46Å; H543-W565 VanDerWaalsContact NE2-NE1 3.15Å
544A70.4Confident75.1Confident6 Ų641.6 Ų41.65%0.0520%0.2CC..EExtended strand (participates in β ladder)trans-99.7129.8176.300000109.9V515 A516 T517V515-A544 HydrophobicContact CG1-CB 4.13Å; A516-A544 CarbonylContact O-C 3.42Å; A516-A544 VanDerWaalsContact O-CA 3.3Å; A516-A544 WeakPolarHBondContact O-CA 3.35Å; T517-A544 HydrophobicContact CG2-CB 4.03Å
545V80.2Confident75.3Confident9 Ų944.4 Ų44.46%0.05522%0.217CC..EExtended strand (participates in β ladder)trans-123.2155.8174.4-74.90000110.3V515 A516 F518 I547 A561 N563V515-V545 WeakPolarHBondContact CA-O 3Å; A516-V545 HydrophobicContact CB-CG2 4.47Å; A516-V545 PolarHBondContact N-O 3.08Å; A516-V545 PolarHBondContact O-N 2.68Å; F518-V545 HydrophobicContact CD1-CG1 4.37Å; F518-V545 HydrophobicContact CD1-CG2 3.82Å; F518-V545 HydrophobicContact CE1-CB 4.25Å; F518-V545 HydrophobicContact CE1-CG1 3.51Å; F518-V545 HydrophobicContact CE1-CG2 3.8Å; F518-V545 HydrophobicContact CZ-CG1 4.22Å; V545-I547 HydrophobicContact CG2-CD1 3.77Å; V545-A561 HydrophobicContact CB-CB 4.33Å; V545-A561 HydrophobicContact CG2-CB 4.3Å; V545-N563 HydrophobicContact CG1-CB 4.35Å
546R80.4Confident75.8Confident32 Ų3244.4 Ų44.412%0.12122%0.219CC..EExtended strand (participates in β ladder)trans-92114.7171.3-177177.671.8-144.70.1108.8I366 I368 P513 I514 I548 A561 A562I366-R546 PolarHBondContact O-NH2 3.38Å; I368-R546 PolarHBondContact O-NH2 2.81Å; P513-R546 HydrophobicContact CB-CG 3.79Å; I514-R546 CarbonylContact O-C 3.44Å; I514-R546 WeakPolarHBondContact O-CA 3.43Å; R546-I548 HydrophobicContact CG-CG2 4.13Å; R546-A561 CarbonylContact O-C 3.59Å; R546-A561 WeakPolarHBondContact O-CA 3.5Å; R546-A562 HydrophobicContact CB-CB 4.38Å; R546-A562 PolarHBondContact N-O 3.22Å; R546-A562 VanDerWaalsContact N-O 3.11Å; R546-A562 PolarHBondContact O-N 3.41Å
547I86.9Confident77.4Confident7 Ų746.6 Ų46.64%0.03623%0.228CC..EExtended strand (participates in β ladder)trans-83.6128.4174.3-49.5-58.6000108.3L508 P513 I514 A516 V545 W559 A561L508-I547 HydrophobicContact CD2-CG2 3.92Å; P513-I547 VanDerWaalsContact CA-O 3.27Å; P513-I547 WeakPolarHBondContact CA-O 3.06Å; I514-I547 HydrophobicContact CG1-CB 3.85Å; I514-I547 HydrophobicContact CG1-CG1 4.3Å; I514-I547 PolarHBondContact N-O 2.89Å; I514-I547 VanDerWaalsContact N-O 3.12Å; I514-I547 PolarHBondContact O-N 3.44Å; A516-I547 HydrophobicContact CB-CD1 3.98Å; A516-I547 HydrophobicContact CB-CG1 3.56Å; V545-I547 HydrophobicContact CG2-CD1 3.77Å; I547-W559 HydrophobicContact CD1-CB 4.38Å; I547-W559 HydrophobicContact CG2-CB 4.28Å; I547-W559 HydrophobicContact CG2-CD2 4.14Å; I547-W559 HydrophobicContact CG2-CE3 3.46Å; I547-W559 VanDerWaalsContact CG2-CE3 3.46Å; I547-W559 HydrophobicContact CG2-CZ3 4.1Å; I547-A561 HydrophobicContact CD1-CB 3.82Å
548I87.1Confident79Confident11 Ų1148.3 Ų48.36%0.05623%0.228CC..EExtended strand (participates in β ladder)trans-120.3-7.3-17662.6168.5000113A355 I366 P513 R546 L560 A562A355-I548 HydrophobicContact CB-CB 4.43Å; A355-I548 WeakPolarHBondContact CB-O 3.07Å; A355-I548 PolarHBondContact N-O 3.07Å; I366-I548 HydrophobicContact CG2-CB 4.16Å; I366-I548 HydrophobicContact CG2-CG2 3.87Å; P513-I548 HydrophobicContact CB-CG2 4.13Å; P513-I548 HydrophobicContact CG-CG2 4.13Å; R546-I548 HydrophobicContact CG-CG2 4.13Å; I548-L560 HydrophobicContact CG1-CB 3.89Å; I548-L560 WeakPolarHBondContact CG1-O 3.32Å; I548-L560 PolarHBondContact N-O 3.47Å; I548-A562 HydrophobicContact CG2-CB 4.43Å
549G90.9Very high80.6Confident0 Ų052 Ų520%024%0.24CC..EExtended strand (participates in β ladder)trans-177.7179-175.500000113.1F353 L560F353-G549 CarbonylContact O-C 3.53Å; F353-G549 WeakPolarHBondContact O-CA 3.06Å; G549-L560 PolarHBondContact N-O 3.45Å; G549-L560 PolarHBondContact O-N 2.77Å
550W94Very high81.5Confident12 Ų1253 Ų535%0.04525%0.246CC..EExtended strand (participates in β ladder)trans-148.6163.9171.564.883.9000110.2L349 P350 E351 E352 F353 M505 L508 Y509 Y558 W559L349-W550 HydrophobicContact CB-CZ2 4.47Å; L349-W550 HydrophobicContact CD2-CH2 4.42Å; P350-W550 HydrophobicContact CG-CZ2 4.03Å; P350-W550 PolarHBondContact O-NE1 2.71Å; E351-W550 VanDerWaalsContact O-CD1 3.25Å; E351-W550 PolarHBondContact O-NE1 2.9Å; E352-W550 WeakPolarHBondContact CA-O 3.26Å; F353-W550 HydrophobicContact CB-CD2 3.65Å; F353-W550 HydrophobicContact CB-CE3 3.81Å; F353-W550 HydrophobicContact CB-CG 4.4Å; F353-W550 HydrophobicContact CB-CH2 3.43Å; F353-W550 VanDerWaalsContact CB-CH2 3.43Å; F353-W550 HydrophobicContact CB-CZ2 3.29Å; F353-W550 HydrophobicContact CB-CZ3 3.71Å; F353-W550 AromaticContact CD1-CE3 3.83Å; F353-W550 HydrophobicContact CD1-CE3 3.83Å; F353-W550 AromaticContact CD1-CH2 3.59Å; F353-W550 HydrophobicContact CD1-CH2 3.59Å; F353-W550 HydrophobicContact CD1-CZ2 4.36Å; F353-W550 AromaticContact CD1-CZ3 3.29Å; F353-W550 HydrophobicContact CD1-CZ3 3.29Å; F353-W550 HydrophobicContact CD2-CH2 4.2Å; F353-W550 HydrophobicContact CE1-CH2 4.41Å; F353-W550 HydrophobicContact CE1-CZ3 4.11Å; F353-W550 HydrophobicContact CG-CD2 4.49Å; F353-W550 HydrophobicContact CG-CE3 4.18Å; F353-W550 AromaticContact CG-CH2 3.47Å; F353-W550 HydrophobicContact CG-CH2 3.47Å; F353-W550 VanDerWaalsContact CG-CH2 3.47Å; F353-W550 AromaticContact CG-CZ2 3.86Å; F353-W550 HydrophobicContact CG-CZ2 3.86Å; F353-W550 AromaticContact CG-CZ3 3.67Å; F353-W550 HydrophobicContact CG-CZ3 3.67Å; F353-W550 PolarHBondContact N-O 2.88Å; F353-W550 PolarHBondContact O-N 2.69Å; M505-W550 HydrophobicContact CB-CE3 4.32Å; M505-W550 HydrophobicContact CB-CH2 4.19Å; M505-W550 HydrophobicContact CB-CZ2 4.42Å; M505-W550 HydrophobicContact CB-CZ3 4.13Å; M505-W550 HydrophobicContact CE-CD2 3.85Å; M505-W550 HydrophobicContact CE-CG 4.02Å; M505-W550 HydrophobicContact CE-CZ2 3.85Å; M505-W550 HydrophobicContact CG-CD2 4.13Å; M505-W550 HydrophobicContact CG-CE3 4.16Å; M505-W550 HydrophobicContact CG-CZ3 4.46Å; L508-W550 HydrophobicContact CB-CZ3 4.02Å; L508-W550 HydrophobicContact CD2-CE3 3.52Å; L508-W550 HydrophobicContact CD2-CZ3 3.58Å; L508-W550 HydrophobicContact CG-CE3 4.25Å; L508-W550 HydrophobicContact CG-CZ3 3.78Å; Y509-W550 HydrophobicContact CD2-CH2 4.16Å; Y509-W550 HydrophobicContact CG-CH2 4.45Å; W550-Y558 CarbonylContact C-O 3.57Å; W550-Y558 WeakPolarHBondContact CA-O 3.48Å; W550-Y558 WeakPolarHBondContact CB-O 3.44Å; W550-W559 HydrophobicContact CB-CE3 3.92Å; W550-W559 HydrophobicContact CB-CZ3 4.18Å; W550-W559 HydrophobicContact CE3-CZ3 4.13Å
551G89.9Confident82.5Confident2 Ų255.7 Ų55.72%0.02127%0.268CS..EExtended strand (participates in β ladder)trans-165.3-173.417300000112.6K557 Y558G551-K557 WeakPolarHBondContact O-CA 3.3Å; G551-Y558 PolarHBondContact N-O 3.13Å; G551-Y558 WeakPolarHBondContact O-CD1 3.47Å; G551-Y558 PolarHBondContact O-N 2.8Å
552K84.3Confident83.1Confident78 Ų7855.3 Ų55.334%0.33926%0.264SS..EExtended strand (participates in β ladder)trans-140.1125.7-178.8-173.2-177.3173.2-168.90110.2D555 E556K552-D555 VanDerWaalsContact CE-CA 3.41Å; K552-D555 WeakPolarHBondContact CE-OD1 3.37Å; K552-D555 IonicContact NZ-OD1 2.89Å; K552-D555 PolarHBondContact NZ-OD1 3.29Å; K552-E556 CarbonylContact C-O 3.51Å; K552-E556 VanDerWaalsContact CA-O 3.31Å; K552-E556 WeakPolarHBondContact CA-O 3.49Å
553E79.1Confident83.7Confident116 Ų11653 Ų5354%0.54226%0.256SS..EExtended strand (participates in β ladder)trans-126124.9176.9-170.3176.1-171.700109I531 D555 E556 Y558I531-E553 HydrophobicContact CD1-CB 3.87Å; E553-D555 VanDerWaalsContact C-N 3.26Å; E553-D555 PolarHBondContact O-N 2.93Å; E553-D555 VanDerWaalsContact O-N 3.09Å; E553-E556 PolarHBondContact N-O 3.05Å; E553-E556 PolarHBondContact O-N 3.31Å; E553-Y558 HydrophobicContact CB-CE1 4.25Å
554E74.3Confident83.3Confident189 Ų18953.4 Ų53.488%0.88326%0.258SS*.THydrogen-bonded Turntrans45.243.4178.4-61-171.1167.800115.1E556E554-E556 PolarHBondContact O-N 3.04Å
555D78.6Confident83.1Confident126 Ų12653.3 Ų53.367%0.67426%0.256SS*.THydrogen-bonded Turntrans79.9-9.3-174.8-69.6-43.6000118.2K552 E553K552-D555 VanDerWaalsContact CE-CA 3.41Å; K552-D555 WeakPolarHBondContact CE-OD1 3.37Å; K552-D555 IonicContact NZ-OD1 2.89Å; K552-D555 PolarHBondContact NZ-OD1 3.29Å; E553-D555 VanDerWaalsContact C-N 3.26Å; E553-D555 PolarHBondContact O-N 2.93Å; E553-D555 VanDerWaalsContact O-N 3.09Å
556E80.1Confident82.3Confident120 Ų12053.3 Ų53.356%0.56126%0.258SS*.EExtended strand (participates in β ladder)trans-90.5123.7176.6-66.1-61.8157.900112I531 K552 E553 E554I531-E556 HydrophobicContact CD1-CB 4.43Å; K552-E556 CarbonylContact C-O 3.51Å; K552-E556 VanDerWaalsContact CA-O 3.31Å; K552-E556 WeakPolarHBondContact CA-O 3.49Å; E553-E556 PolarHBondContact N-O 3.05Å; E553-E556 PolarHBondContact O-N 3.31Å; E554-E556 PolarHBondContact O-N 3.04Å
557K87.6Confident81.4Confident132 Ų13253.9 Ų53.957%0.57427%0.266SS*.EExtended strand (participates in β ladder)trans-83.2142.2174.4-65.8-178.9176.8-175.40110.7E501 G551E501-K557 WeakPolarHBondContact OE1-CD 3.46Å; E501-K557 IonicContact OE1-NZ 3.04Å; E501-K557 PolarHBondContact OE1-NZ 2.73Å; E501-K557 IonicContact OE2-NZ 3.04Å; E501-K557 PolarHBondContact OE2-NZ 3.28Å; G551-K557 WeakPolarHBondContact O-CA 3.3Å
558Y88.5Confident80.1Confident58 Ų5855.1 Ų55.123%0.22728%0.28CS..EExtended strand (participates in β ladder)trans-139157.3177.964.9-94.1000113I531 W550 G551 E553 L560I531-Y558 HydrophobicContact CD1-CD1 3.5Å; I531-Y558 VanDerWaalsContact CD1-CD1 3.5Å; I531-Y558 HydrophobicContact CD1-CE1 4.24Å; I531-Y558 HydrophobicContact CD1-CG 4.08Å; I531-Y558 HydrophobicContact CG1-CD1 3.95Å; I531-Y558 HydrophobicContact CG1-CG 4.08Å; W550-Y558 CarbonylContact C-O 3.57Å; W550-Y558 WeakPolarHBondContact CA-O 3.48Å; W550-Y558 WeakPolarHBondContact CB-O 3.44Å; G551-Y558 PolarHBondContact N-O 3.13Å; G551-Y558 WeakPolarHBondContact O-CD1 3.47Å; G551-Y558 PolarHBondContact O-N 2.8Å; E553-Y558 HydrophobicContact CB-CE1 4.25Å; Y558-L560 HydrophobicContact CD2-CD2 4.21Å; Y558-L560 HydrophobicContact CD2-CG 4.38Å; Y558-L560 HydrophobicContact CE2-CD2 3.69Å; Y558-L560 HydrophobicContact CE2-CG 3.91Å
559W92.3Very high79.2Confident97 Ų9755.9 Ų55.937%0.36728%0.282SS..EExtended strand (participates in β ladder)trans-100134.6169-65.5102.6000110.2E501 M504 M505 L508 I547 W550 A561E501-W559 HydrophobicContact CG-CZ2 4.18Å; M504-W559 HydrophobicContact CB-CH2 3.68Å; M504-W559 HydrophobicContact CB-CZ2 4.19Å; M504-W559 HydrophobicContact CB-CZ3 4.5Å; M504-W559 HydrophobicContact CE-CH2 4.32Å; M504-W559 HydrophobicContact CE-CZ2 4.1Å; M504-W559 HydrophobicContact SD-CZ2 4.44Å; M505-W559 HydrophobicContact CG-CH2 3.58Å; M505-W559 HydrophobicContact CG-CZ3 4.02Å; L508-W559 HydrophobicContact CD2-CZ3 4.38Å; I547-W559 HydrophobicContact CD1-CB 4.38Å; I547-W559 HydrophobicContact CG2-CB 4.28Å; I547-W559 HydrophobicContact CG2-CD2 4.14Å; I547-W559 HydrophobicContact CG2-CE3 3.46Å; I547-W559 VanDerWaalsContact CG2-CE3 3.46Å; I547-W559 HydrophobicContact CG2-CZ3 4.1Å; W550-W559 HydrophobicContact CB-CE3 3.92Å; W550-W559 HydrophobicContact CB-CZ3 4.18Å; W550-W559 HydrophobicContact CE3-CZ3 4.13Å; W559-A561 PolarHBondContact O-N 3.3Å
560L89.1Confident78.2Confident44 Ų4456.2 Ų56.223%0.2329%0.285CS..EExtended strand (participates in β ladder)trans-81.3112.1165.9-66.5174.4000108.6D354 I548 G549 Y558D354-L560 HydrophobicContact CB-CD1 4.28Å; I548-L560 HydrophobicContact CG1-CB 3.89Å; I548-L560 WeakPolarHBondContact CG1-O 3.32Å; I548-L560 PolarHBondContact N-O 3.47Å; G549-L560 PolarHBondContact N-O 3.45Å; G549-L560 PolarHBondContact O-N 2.77Å; Y558-L560 HydrophobicContact CD2-CD2 4.21Å; Y558-L560 HydrophobicContact CD2-CG 4.38Å; Y558-L560 HydrophobicContact CE2-CD2 3.69Å; Y558-L560 HydrophobicContact CE2-CG 3.91Å
561A87.1Confident76.8Confident56 Ų5660.9 Ų60.946%0.46331%0.307SS..EExtended strand (participates in β ladder)trans-119.3129.4-177.200000112V545 R546 I547 W559V545-A561 HydrophobicContact CB-CB 4.33Å; V545-A561 HydrophobicContact CG2-CB 4.3Å; R546-A561 CarbonylContact O-C 3.59Å; R546-A561 WeakPolarHBondContact O-CA 3.5Å; I547-A561 HydrophobicContact CD1-CB 3.82Å; W559-A561 PolarHBondContact O-N 3.3Å
562A78.7Confident75.2Confident7 Ų764 Ų646%0.05832%0.324CS..EExtended strand (participates in β ladder)trans-90.6112.516700000109.3I369 R546 I548I369-A562 HydrophobicContact CD1-CB 3.74Å; R546-A562 HydrophobicContact CB-CB 4.38Å; R546-A562 PolarHBondContact N-O 3.22Å; R546-A562 VanDerWaalsContact N-O 3.11Å; R546-A562 PolarHBondContact O-N 3.41Å; I548-A562 HydrophobicContact CG2-CB 4.43Å
563N82Confident73.6Confident12 Ų1263.4 Ų63.46%0.06433%0.333CS..  trans-82.5169.7175.6-156.6-5.6000111.7I369 H543 V545 W565 W569I369-N563 WeakPolarHBondContact CG2-O 3.23Å; H543-N563 PolarHBondContact CD2-OD1 2.97Å; H543-N563 PolarHBondContact NE2-OD1 3.05Å; V545-N563 HydrophobicContact CG1-CB 4.35Å; N563-W565 VanDerWaalsContact ND2-CE2 3.32Å; N563-W565 WeakPolarHBondContact ND2-CZ3 3.17Å; N563-W569 HydrophobicContact CB-CE3 3.99Å; N563-W569 HydrophobicContact CB-CH2 4.41Å; N563-W569 HydrophobicContact CB-CZ3 3.55Å; N563-W569 WeakPolarHBondContact ND2-CH2 3.46Å; N563-W569 VanDerWaalsContact ND2-CZ3 3.25Å; N563-W569 WeakPolarHBondContact ND2-CZ3 3.49Å
564S68.5Low71.8Confident8 Ų866.2 Ų66.26%0.05634%0.339CS..SBendtrans-10829.3-179.862.90000113.3K370 D371 Q372K370-S564 CarbonylContact O-C 3.58Å; K370-S564 WeakPolarHBondContact O-CA 3.12Å; D371-S564 CarbonylContact C-O 3.58Å; D371-S564 WeakPolarHBondContact CA-O 3.5Å; Q372-S564 WeakPolarHBondContact CG-O 3.04Å; Q372-S564 PolarHBondContact N-O 3.16Å; Q372-S564 PolarHBondContact OE1-OG 3.45Å
565W66.3Low70.3Confident3 Ų360.5 Ų60.51%0.01132%0.324CS..BIsolated β-bridgetrans-108.122.7-176.2-57.5-11.7000114R311 F312 F323 L324 K370 L524 H543 N563 W569R311-W565 VanDerWaalsContact NH1-CA 3.32Å; R311-W565 PolarHBondContact NH1-O 2.79Å; F312-W565 HydrophobicContact CE1-CZ3 4.46Å; F312-W565 AromaticContact CE2-CE3 3.97Å; F312-W565 HydrophobicContact CE2-CE3 3.97Å; F312-W565 AromaticContact CE2-CZ3 3.87Å; F312-W565 HydrophobicContact CE2-CZ3 3.87Å; F312-W565 AromaticContact CZ-CD2 3.93Å; F312-W565 HydrophobicContact CZ-CD2 3.93Å; F312-W565 AromaticContact CZ-CE3 3.44Å; F312-W565 HydrophobicContact CZ-CE3 3.44Å; F312-W565 VanDerWaalsContact CZ-CE3 3.44Å; F312-W565 AromaticContact CZ-CH2 3.83Å; F312-W565 HydrophobicContact CZ-CH2 3.83Å; F312-W565 HydrophobicContact CZ-CZ2 4.29Å; F312-W565 AromaticContact CZ-CZ3 3.39Å; F312-W565 HydrophobicContact CZ-CZ3 3.39Å; F323-W565 AromaticContact CE1-CD1 3.72Å; F323-W565 HydrophobicContact CE1-CD2 4.38Å; F323-W565 AromaticContact CE1-CE2 3.85Å; F323-W565 HydrophobicContact CE1-CG 4.33Å; F323-W565 HydrophobicContact CE1-CZ2 4.43Å; F323-W565 AromaticContact CE1-NE1 3.42Å; F323-W565 AromaticContact CZ-CD1 3.68Å; F323-W565 HydrophobicContact CZ-CG 4.27Å; F323-W565 AromaticContact CZ-NE1 3.89Å; L324-W565 HydrophobicContact CD2-CH2 4.41Å; L324-W565 HydrophobicContact CD2-CZ2 3.7Å; K370-W565 PolarHBondContact O-N 3.44Å; L524-W565 HydrophobicContact CD2-CH2 3.93Å; L524-W565 HydrophobicContact CD2-CZ3 4.4Å; L524-W565 HydrophobicContact CG-CH2 4.36Å; L524-W565 HydrophobicContact CG-CZ3 4.42Å; H543-W565 AromaticContact CD2-CZ2 3.83Å; H543-W565 AromaticContact CD2-NE1 3.89Å; H543-W565 AromaticContact CE1-NE1 3.45Å; H543-W565 PolarHBondContact CE1-NE1 3.14Å; H543-W565 AromaticContact NE2-CE2 3.75Å; H543-W565 AromaticContact NE2-NE1 3.15Å; H543-W565 PolarHBondContact NE2-NE1 3.46Å; H543-W565 VanDerWaalsContact NE2-NE1 3.15Å; N563-W565 VanDerWaalsContact ND2-CE2 3.32Å; N563-W565 WeakPolarHBondContact ND2-CZ3 3.17Å; W565-W569 HydrophobicContact CB-CB 4.22Å; W565-W569 HydrophobicContact CB-CG 4.42Å; W565-W569 HydrophobicContact CD2-CD2 4.48Å; W565-W569 AromaticContact CE3-CD1 3.68Å; W565-W569 AromaticContact CE3-CD2 3.44Å; W565-W569 HydrophobicContact CE3-CD2 3.44Å; W565-W569 VanDerWaalsContact CE3-CD2 3.44Å; W565-W569 AromaticContact CE3-CE2 3.34Å; W565-W569 AromaticContact CE3-CE3 3.98Å; W565-W569 HydrophobicContact CE3-CE3 3.98Å; W565-W569 AromaticContact CE3-CG 3.73Å; W565-W569 HydrophobicContact CE3-CG 3.73Å; W565-W569 HydrophobicContact CE3-CH2 4.29Å; W565-W569 AromaticContact CE3-CZ2 3.8Å; W565-W569 HydrophobicContact CE3-CZ2 3.8Å; W565-W569 HydrophobicContact CE3-CZ3 4.37Å; W565-W569 AromaticContact CE3-NE1 3.53Å; W565-W569 HydrophobicContact CH2-CZ2 4.47Å; W565-W569 AromaticContact CZ3-CD2 3.98Å; W565-W569 HydrophobicContact CZ3-CD2 3.98Å; W565-W569 AromaticContact CZ3-CE2 3.35Å; W565-W569 HydrophobicContact CZ3-CG 4.47Å; W565-W569 HydrophobicContact CZ3-CH2 4.12Å; W565-W569 AromaticContact CZ3-CZ2 3.44Å; W565-W569 HydrophobicContact CZ3-CZ2 3.44Å; W565-W569 VanDerWaalsContact CZ3-CZ2 3.44Å; W565-W569 AromaticContact CZ3-NE1 3.5Å
566G61.8Low69.1Low9 Ų956.4 Ų56.49%0.09331%0.308CS..  trans71.9176.6179.100000113.8I369 K370 G568I369-G566 WeakPolarHBondContact CG2-O 3.2Å; K370-G566 PolarHBondContact O-N 2.67Å; G566-G568 VanDerWaalsContact C-N 3.27Å; G566-G568 PolarHBondContact O-N 3.05Å
567T62.8Low68.7Low45 Ų4552 Ų5228%0.27629%0.286SS..THydrogen-bonded Turntrans-76.7-10.5-175.355.10000113.9I369 W569 N572 A573I369-T567 HydrophobicContact CB-CG2 4.46Å; T567-W569 VanDerWaalsContact C-N 3.3Å; T567-W569 PolarHBondContact O-N 3Å; T567-N572 CarbonylContact O-C 3.53Å; T567-A573 WeakPolarHBondContact O-CA 3.34Å; T567-A573 PolarHBondContact O-N 3.39Å
568G59.5Low68.5Low32 Ų3245.8 Ų45.833%0.3326%0.259SS..THydrogen-bonded Turntrans-80.5-2.6178.200000115.2G566G566-G568 VanDerWaalsContact C-N 3.27Å; G566-G568 PolarHBondContact O-N 3.05Å
569W67.3Low68.3Low28 Ų2845.3 Ų45.311%0.10626%0.259CS..SBendtrans-120.8144-179.8-179.497.2000111.4F312 L524 Y527 N563 W565 T567F312-W569 AromaticContact CE2-CD1 3.79Å; F312-W569 AromaticContact CE2-NE1 3.89Å; L524-W569 HydrophobicContact CD1-CH2 4.12Å; L524-W569 HydrophobicContact CD1-CZ2 3.81Å; L524-W569 HydrophobicContact CG-CZ2 3.95Å; Y527-W569 AromaticContact CD1-CH2 3.74Å; Y527-W569 HydrophobicContact CD1-CH2 3.74Å; Y527-W569 AromaticContact CD1-CZ2 3.63Å; Y527-W569 HydrophobicContact CD1-CZ2 3.63Å; Y527-W569 HydrophobicContact CD1-CZ3 4.41Å; Y527-W569 HydrophobicContact CE1-CH2 4.23Å; Y527-W569 HydrophobicContact CG-CZ2 4.35Å; N563-W569 HydrophobicContact CB-CE3 3.99Å; N563-W569 HydrophobicContact CB-CH2 4.41Å; N563-W569 HydrophobicContact CB-CZ3 3.55Å; N563-W569 WeakPolarHBondContact ND2-CH2 3.46Å; N563-W569 VanDerWaalsContact ND2-CZ3 3.25Å; N563-W569 WeakPolarHBondContact ND2-CZ3 3.49Å; W565-W569 HydrophobicContact CB-CB 4.22Å; W565-W569 HydrophobicContact CB-CG 4.42Å; W565-W569 HydrophobicContact CD2-CD2 4.48Å; W565-W569 AromaticContact CE3-CD1 3.68Å; W565-W569 AromaticContact CE3-CD2 3.44Å; W565-W569 HydrophobicContact CE3-CD2 3.44Å; W565-W569 VanDerWaalsContact CE3-CD2 3.44Å; W565-W569 AromaticContact CE3-CE2 3.34Å; W565-W569 AromaticContact CE3-CE3 3.98Å; W565-W569 HydrophobicContact CE3-CE3 3.98Å; W565-W569 AromaticContact CE3-CG 3.73Å; W565-W569 HydrophobicContact CE3-CG 3.73Å; W565-W569 HydrophobicContact CE3-CH2 4.29Å; W565-W569 AromaticContact CE3-CZ2 3.8Å; W565-W569 HydrophobicContact CE3-CZ2 3.8Å; W565-W569 HydrophobicContact CE3-CZ3 4.37Å; W565-W569 AromaticContact CE3-NE1 3.53Å; W565-W569 HydrophobicContact CH2-CZ2 4.47Å; W565-W569 AromaticContact CZ3-CD2 3.98Å; W565-W569 HydrophobicContact CZ3-CD2 3.98Å; W565-W569 AromaticContact CZ3-CE2 3.35Å; W565-W569 HydrophobicContact CZ3-CG 4.47Å; W565-W569 HydrophobicContact CZ3-CH2 4.12Å; W565-W569 AromaticContact CZ3-CZ2 3.44Å; W565-W569 HydrophobicContact CZ3-CZ2 3.44Å; W565-W569 VanDerWaalsContact CZ3-CZ2 3.44Å; W565-W569 AromaticContact CZ3-NE1 3.5Å; T567-W569 VanDerWaalsContact C-N 3.3Å; T567-W569 PolarHBondContact O-N 3Å
570G70.4Confident67.6Low6 Ų644.7 Ų44.76%0.06226%0.263CS..G310 helixtrans71-160.2-175.700000113.3K528 N572 A573K528-G570 CarbonylContact O-C 3.33Å; K528-G570 WeakPolarHBondContact O-CA 3.46Å; G570-N572 PolarHBondContact O-N 2.86Å; G570-A573 PolarHBondContact O-N 3.43Å; G570-A573 VanDerWaalsContact O-N 3.16Å
571E64.2Low67.1Low110 Ų11043.3 Ų43.351%0.51426%0.255SS..G310 helixtrans-62.5-14-172.4-64.4-171166.100114.8K528 G530K528-E571 PolarHBondContact O-N 3.16Å; G530-E571 PolarHBondContact N-OE1 3.07Å
572N56.9Low66.9Low69 Ų6942.7 Ų42.737%0.36924%0.241SC..G310 helixtrans-85.1-2.1179.9-71.4-39.6000114.3I369 T567 G570 R574I369-N572 WeakPolarHBondContact CG1-ND2 3.21Å; T567-N572 CarbonylContact O-C 3.53Å; G570-N572 PolarHBondContact O-N 2.86Å; N572-R574 PolarHBondContact O-N 3.11Å
573A50.2Low66.7Low65 Ų6544.8 Ų44.854%0.53726%0.259SS..  trans-7062.1174.800000111.9T567 G570T567-A573 WeakPolarHBondContact O-CA 3.34Å; T567-A573 PolarHBondContact O-N 3.39Å; G570-A573 PolarHBondContact O-N 3.43Å; G570-A573 VanDerWaalsContact O-N 3.16Å
574R41.5Very low66.1Low175 Ų17547.9 Ų47.966%0.6627%0.273SS*.  trans-88.5159.3-176.7-75.4-176.6171.9138.5-0.9112.2N572 A576 Y577N572-R574 PolarHBondContact O-N 3.11Å; R574-A576 PolarHBondContact O-N 2.98Å; R574-Y577 PolarHBondContact O-N 3.04Å
575A43.2Very low66.4Low69 Ų6948 Ų4857%0.5727%0.273SS*.THydrogen-bonded Turntrans-59.3-11.2179.800000115.5G610A575-G610 CarbonylContact O-C 3.47Å
576A52.3Low66.9Low40 Ų4051.4 Ų51.433%0.33129%0.288SS..THydrogen-bonded Turntrans-90.410.8178.600000114.4R574 Y578 E579 D580R574-A576 PolarHBondContact O-N 2.98Å; A576-Y578 VanDerWaalsContact C-N 3.25Å; A576-Y578 PolarHBondContact O-N 2.95Å; A576-E579 PolarHBondContact O-N 2.77Å; A576-E579 VanDerWaalsContact O-N 3.12Å; A576-D580 PolarHBondContact O-N 3.43Å
577Y73.3Confident67.1Low28 Ų2858.7 Ų58.711%0.1132%0.317CS..Hα-helixtrans-47.5-42.4-175.9175.1-85.7000114.2R574 D580 H581 F613 M616R574-Y577 PolarHBondContact O-N 3.04Å; Y577-D580 PolarHBondContact O-N 2.63Å; Y577-H581 HydrophobicContact CE1-CB 4.14Å; Y577-H581 HydrophobicContact CE2-CB 4.43Å; Y577-H581 WeakPolarHBondContact O-CB 3.32Å; Y577-H581 PolarHBondContact O-N 3.31Å; Y577-F613 HydrophobicContact CD1-CB 3.79Å; Y577-F613 HydrophobicContact CD1-CD2 4.17Å; Y577-F613 HydrophobicContact CD1-CG 4.49Å; Y577-F613 HydrophobicContact CD2-CB 4Å; Y577-F613 HydrophobicContact CE1-CB 3.98Å; Y577-F613 AromaticContact CE1-CD2 3.47Å; Y577-F613 HydrophobicContact CE1-CD2 3.47Å; Y577-F613 VanDerWaalsContact CE1-CD2 3.47Å; Y577-F613 HydrophobicContact CE1-CE2 4.4Å; Y577-F613 HydrophobicContact CE1-CG 4.19Å; Y577-F613 HydrophobicContact CE2-CB 4.16Å; Y577-F613 HydrophobicContact CE2-CD2 4.04Å; Y577-F613 HydrophobicContact CE2-CG 4.35Å; Y577-F613 HydrophobicContact CG-CB 3.8Å; Y577-F613 AromaticContact CZ-CD2 3.38Å; Y577-F613 WeakPolarHBondContact OH-CD2 3.5Å; Y577-M616 HydrophobicContact CD1-CE 3.27Å; Y577-M616 HydrophobicContact CE1-CE 3.44Å; Y577-M616 VanDerWaalsContact CE1-CE 3.44Å
578Y83.1Confident67.1Low0 Ų058.4 Ų58.40%032%0.319CS..Hα-helixtrans-61.8-46.5-177.6-179.5-113.8000112.9A576 Y582 L604 N605 F608 M611 M616 Y815 Y816A576-Y578 VanDerWaalsContact C-N 3.25Å; A576-Y578 PolarHBondContact O-N 2.95Å; Y578-Y582 WeakPolarHBondContact O-CB 3.48Å; Y578-Y582 PolarHBondContact O-N 3.25Å; Y578-Y582 VanDerWaalsContact O-N 3.08Å; Y578-L604 HydrophobicContact CD1-CD2 3.89Å; Y578-L604 HydrophobicContact CE1-CD2 3.36Å; Y578-N605 PolarHBondContact OH-N 3.46Å; Y578-F608 WeakPolarHBondContact CB-O 2.91Å; Y578-F608 HydrophobicContact CD1-CB 3.71Å; Y578-F608 VanDerWaalsContact CD1-O 3.23Å; Y578-F608 WeakPolarHBondContact CD1-O 3.03Å; Y578-F608 HydrophobicContact CD2-CB 3.6Å; Y578-F608 HydrophobicContact CD2-CG 4.37Å; Y578-F608 HydrophobicContact CE1-CB 3.62Å; Y578-F608 HydrophobicContact CE2-CB 3.52Å; Y578-F608 AromaticContact CE2-CD2 3.86Å; Y578-F608 HydrophobicContact CE2-CD2 3.86Å; Y578-F608 HydrophobicContact CE2-CG 4.05Å; Y578-F608 HydrophobicContact CG-CB 3.69Å; Y578-M611 PolarHBondContact N-O 3.41Å; Y578-M616 HydrophobicContact CD2-CE 4.15Å; Y578-M616 HydrophobicContact CD2-SD 3.54Å; Y578-M616 VanDerWaalsContact CD2-SD 3.54Å; Y578-M616 HydrophobicContact CE2-SD 4.31Å; Y578-M616 HydrophobicContact CG-SD 4.2Å; Y578-Y815 PolarHBondContact OH-O 2.77Å; Y578-Y816 HydrophobicContact CD2-CD1 4.43Å; Y578-Y816 AromaticContact CD2-CE1 3.53Å; Y578-Y816 HydrophobicContact CD2-CE1 3.53Å; Y578-Y816 AromaticContact CD2-CZ 3.78Å; Y578-Y816 HydrophobicContact CE1-CE1 4.34Å; Y578-Y816 AromaticContact CE2-CD1 3.54Å; Y578-Y816 HydrophobicContact CE2-CD1 3.54Å; Y578-Y816 AromaticContact CE2-CE1 3.05Å; Y578-Y816 HydrophobicContact CE2-CE1 3.05Å; Y578-Y816 HydrophobicContact CE2-CG 4.44Å; Y578-Y816 AromaticContact CE2-CZ 3.64Å; Y578-Y816 HydrophobicContact CG-CE1 4.33Å; Y578-Y816 AromaticContact CZ-CD1 3.71Å; Y578-Y816 AromaticContact CZ-CE1 3.52Å; Y578-Y816 WeakPolarHBondContact O-CE1 3.33Å; Y578-Y816 PolarHBondContact O-OH 3.06Å
579E84.1Confident67.6Low49 Ų4959.7 Ų59.723%0.22932%0.315CS..Hα-helixtrans-69.8-41.9176.9-76.274.7-166.400112.5A576 Y582 A583 R609 G610A576-E579 PolarHBondContact O-N 2.77Å; A576-E579 VanDerWaalsContact O-N 3.12Å; E579-Y582 WeakPolarHBondContact O-CB 3.46Å; E579-Y582 PolarHBondContact O-N 3.26Å; E579-A583 PolarHBondContact O-N 3.44Å; E579-R609 VanDerWaalsContact OE1-CA 3.25Å; E579-R609 WeakPolarHBondContact OE1-CA 3.25Å; E579-R609 WeakPolarHBondContact OE1-CD 3.1Å; E579-R609 IonicContact OE1-NH1 3.83Å; E579-G610 PolarHBondContact OE1-N 3.18Å; E579-G610 WeakPolarHBondContact OE2-CA 3.39Å; E579-G610 PolarHBondContact OE2-N 3.11Å
580D76.8Confident67.5Low84 Ų8464 Ų6445%0.44934%0.337SS..Hα-helixtrans-65.5-46.1-179.7-66.3-21.7000111A576 Y577 Y582 A583 E584A576-D580 PolarHBondContact O-N 3.43Å; Y577-D580 PolarHBondContact O-N 2.63Å; D580-Y582 VanDerWaalsContact C-N 3.28Å; D580-Y582 PolarHBondContact O-N 3.06Å; D580-A583 PolarHBondContact O-N 2.98Å; D580-A583 VanDerWaalsContact O-N 3.16Å; D580-E584 PolarHBondContact O-N 3.08Å
581H79.4Confident66.7Low15 Ų1568.2 Ų68.27%0.06936%0.361CS..Hα-helixtrans-68.7-28.3176.9-170.959000112.1Y577 E584 L585 S812 Y816Y577-H581 HydrophobicContact CE1-CB 4.14Å; Y577-H581 HydrophobicContact CE2-CB 4.43Å; Y577-H581 WeakPolarHBondContact O-CB 3.32Å; Y577-H581 PolarHBondContact O-N 3.31Å; H581-E584 IonicContact CE1-OE2 2.7Å; H581-E584 IonicContact CG-OE2 3.1Å; H581-E584 IonicContact ND1-OE2 3.96Å; H581-E584 PolarHBondContact ND1-OE2 2.72Å; H581-E584 PolarHBondContact O-N 3.03Å; H581-L585 WeakPolarHBondContact O-CB 3.26Å; H581-L585 WeakPolarHBondContact O-CG 3.34Å; H581-L585 PolarHBondContact O-N 2.91Å; H581-S812 WeakPolarHBondContact NE2-CB 2.96Å; H581-S812 PolarHBondContact NE2-OG 3.39Å; H581-Y816 WeakPolarHBondContact CB-OH 3.45Å; H581-Y816 AromaticContact CD2-CE2 3.69Å; H581-Y816 AromaticContact CD2-CZ 3.96Å; H581-Y816 PolarHBondContact CD2-OH 3.01Å
582Y82.2Confident65.7Low42 Ų4272.9 Ų72.917%0.16538%0.38CS..Hα-helixtrans-64.2-46.7168.6176.8-103.7000111.8Y578 E579 D580 E584 L585 K586 F602 L604 Y816Y578-Y582 WeakPolarHBondContact O-CB 3.48Å; Y578-Y582 PolarHBondContact O-N 3.25Å; Y578-Y582 VanDerWaalsContact O-N 3.08Å; E579-Y582 WeakPolarHBondContact O-CB 3.46Å; E579-Y582 PolarHBondContact O-N 3.26Å; D580-Y582 VanDerWaalsContact C-N 3.28Å; D580-Y582 PolarHBondContact O-N 3.06Å; Y582-E584 PolarHBondContact O-N 3Å; Y582-L585 PolarHBondContact O-N 2.81Å; Y582-K586 HydrophobicContact CD1-CB 4.47Å; Y582-K586 HydrophobicContact CD1-CD 4.44Å; Y582-K586 HydrophobicContact CE1-CB 4.24Å; Y582-K586 HydrophobicContact CE1-CD 3.65Å; Y582-K586 HydrophobicContact CE1-CG 4.37Å; Y582-K586 WeakPolarHBondContact O-CA 3.33Å; Y582-K586 WeakPolarHBondContact O-CB 2.87Å; Y582-K586 PolarHBondContact O-N 3.21Å; Y582-F602 HydrophobicContact CD2-CD1 4.41Å; Y582-F602 AromaticContact CD2-CE1 3.46Å; Y582-F602 HydrophobicContact CD2-CE1 3.46Å; Y582-F602 VanDerWaalsContact CD2-CE1 3.46Å; Y582-F602 AromaticContact CD2-CZ 3.58Å; Y582-F602 HydrophobicContact CD2-CZ 3.58Å; Y582-F602 AromaticContact CE2-CD1 3.8Å; Y582-F602 HydrophobicContact CE2-CD1 3.8Å; Y582-F602 AromaticContact CE2-CE1 3.23Å; Y582-F602 HydrophobicContact CE2-CE1 3.23Å; Y582-F602 AromaticContact CE2-CZ 3.83Å; Y582-F602 HydrophobicContact CE2-CZ 3.83Å; Y582-L604 HydrophobicContact CD1-CD1 3.33Å; Y582-L604 HydrophobicContact CD1-CD2 3.93Å; Y582-L604 HydrophobicContact CD1-CG 3.6Å; Y582-L604 HydrophobicContact CD2-CD1 4.34Å; Y582-L604 HydrophobicContact CD2-CD2 3.96Å; Y582-L604 HydrophobicContact CD2-CG 3.69Å; Y582-L604 HydrophobicContact CE1-CD1 3.32Å; Y582-L604 HydrophobicContact CE1-CG 3.76Å; Y582-L604 HydrophobicContact CE2-CD1 4.34Å; Y582-L604 HydrophobicContact CE2-CG 3.86Å; Y582-L604 HydrophobicContact CG-CD1 3.85Å; Y582-L604 HydrophobicContact CG-CD2 3.55Å; Y582-L604 HydrophobicContact CG-CG 3.54Å; Y582-Y816 AromaticContact CD2-CD1 3.64Å; Y582-Y816 HydrophobicContact CD2-CD1 3.64Å; Y582-Y816 AromaticContact CD2-CE1 3.98Å; Y582-Y816 HydrophobicContact CD2-CE1 3.98Å; Y582-Y816 HydrophobicContact CD2-CG 4.36Å; Y582-Y816 HydrophobicContact CG-CD1 4.35Å; Y582-Y816 HydrophobicContact CG-CE1 4.24Å; Y582-Y816 PolarHBondContact N-OH 3.36Å
583A74.8Confident65Low52 Ų5271.9 Ų71.943%0.4338%0.382SS..Hα-helixtrans-60.8-36.6179.200000111.7E579 D580E579-A583 PolarHBondContact O-N 3.44Å; D580-A583 PolarHBondContact O-N 2.98Å; D580-A583 VanDerWaalsContact O-N 3.16Å
584E69.3Low64.5Low77 Ų7773.4 Ų73.436%0.3638%0.381SS..Hα-helixtrans-62.2-56.9172.8-174.7-166.4170.800112D580 H581 Y582 K586 K587D580-E584 PolarHBondContact O-N 3.08Å; H581-E584 IonicContact CE1-OE2 2.7Å; H581-E584 IonicContact CG-OE2 3.1Å; H581-E584 IonicContact ND1-OE2 3.96Å; H581-E584 PolarHBondContact ND1-OE2 2.72Å; H581-E584 PolarHBondContact O-N 3.03Å; Y582-E584 PolarHBondContact O-N 3Å; E584-K586 PolarHBondContact O-N 3.06Å; E584-K587 PolarHBondContact O-N 3.35Å
585L74.5Confident64.7Low10 Ų1068.9 Ų68.95%0.05239%0.388CS..Hα-helixtrans-67.7-35-178.2-72.8-178.9000112.4H581 Y582 K587 A588 F589 F602 D813 Y816 K826H581-L585 WeakPolarHBondContact O-CB 3.26Å; H581-L585 WeakPolarHBondContact O-CG 3.34Å; H581-L585 PolarHBondContact O-N 2.91Å; Y582-L585 PolarHBondContact O-N 2.81Å; L585-K587 VanDerWaalsContact C-N 3.27Å; L585-K587 PolarHBondContact O-N 3.46Å; L585-A588 CarbonylContact O-C 3.45Å; L585-A588 WeakPolarHBondContact O-CA 3.48Å; L585-A588 WeakPolarHBondContact O-CB 3.37Å; L585-A588 PolarHBondContact O-N 3.46Å; L585-F589 HydrophobicContact CB-CD2 4.43Å; L585-F589 WeakPolarHBondContact O-CD2 3.49Å; L585-F589 PolarHBondContact O-N 3.16Å; L585-F602 HydrophobicContact CB-CE1 4.25Å; L585-F602 HydrophobicContact CB-CE2 4.02Å; L585-F602 HydrophobicContact CB-CZ 3.45Å; L585-F602 VanDerWaalsContact CB-CZ 3.45Å; L585-F602 HydrophobicContact CD1-CE2 4.04Å; L585-F602 HydrophobicContact CD1-CZ 4.15Å; L585-F602 HydrophobicContact CG-CZ 4.48Å; L585-D813 HydrophobicContact CD1-CB 4.41Å; L585-Y816 HydrophobicContact CD1-CD2 3.83Å; L585-Y816 HydrophobicContact CD1-CE2 3.67Å; L585-K826 HydrophobicContact CD2-CB 3.89Å
586K76.8Confident64.8Low75 Ų7574 Ų7433%0.32640%0.4SS..Hα-helixtrans-55.5-43.3178.7179.6-179.8172.9-172.50110.9Y582 E584 A588 F589 E590 F602Y582-K586 HydrophobicContact CD1-CB 4.47Å; Y582-K586 HydrophobicContact CD1-CD 4.44Å; Y582-K586 HydrophobicContact CE1-CB 4.24Å; Y582-K586 HydrophobicContact CE1-CD 3.65Å; Y582-K586 HydrophobicContact CE1-CG 4.37Å; Y582-K586 WeakPolarHBondContact O-CA 3.33Å; Y582-K586 WeakPolarHBondContact O-CB 2.87Å; Y582-K586 PolarHBondContact O-N 3.21Å; E584-K586 PolarHBondContact O-N 3.06Å; K586-A588 PolarHBondContact O-N 3.22Å; K586-F589 PolarHBondContact O-N 2.99Å; K586-F589 VanDerWaalsContact O-N 3.13Å; K586-E590 WeakPolarHBondContact CE-OE1 3.45Å; K586-E590 VanDerWaalsContact CE-OE2 3.3Å; K586-E590 WeakPolarHBondContact CE-OE2 3.49Å; K586-E590 HydrophobicContact CG-CG 3.97Å; K586-E590 IonicContact NZ-OE1 3.68Å; K586-E590 PolarHBondContact NZ-OE1 2.95Å; K586-E590 WeakPolarHBondContact O-CB 3.39Å; K586-E590 WeakPolarHBondContact O-CG 3.35Å; K586-E590 PolarHBondContact O-N 2.96Å; K586-F602 HydrophobicContact CB-CE1 4.15Å
587K66.6Low65Low162 Ų16281.8 Ų81.870%0.70443%0.427SS*.Hα-helixtrans-57.7-38.9174.9-71.4178.8179.8178.90112E584 L585 T591E584-K587 PolarHBondContact O-N 3.35Å; L585-K587 VanDerWaalsContact C-N 3.27Å; L585-K587 PolarHBondContact O-N 3.46Å; K587-T591 PolarHBondContact O-N 3.17Å; K587-T591 PolarHBondContact O-OG1 3.27Å
588A63.6Low64.7Low39 Ų3983.2 Ų83.232%0.32244%0.441SS..Hα-helixtrans-74.7-27.417800000113.9L585 K586L585-A588 CarbonylContact O-C 3.45Å; L585-A588 WeakPolarHBondContact O-CA 3.48Å; L585-A588 WeakPolarHBondContact O-CB 3.37Å; L585-A588 PolarHBondContact O-N 3.46Å; K586-A588 PolarHBondContact O-N 3.22Å
589F68.5Low64.5Low59 Ų5984.8 Ų84.826%0.25945%0.452SS..Hα-helixtrans-86.8-26.6174.5-82.9-88.3000113.3L585 K586 W600 F602 K825L585-F589 HydrophobicContact CB-CD2 4.43Å; L585-F589 WeakPolarHBondContact O-CD2 3.49Å; L585-F589 PolarHBondContact O-N 3.16Å; K586-F589 PolarHBondContact O-N 2.99Å; K586-F589 VanDerWaalsContact O-N 3.13Å; F589-W600 HydrophobicContact CE1-CH2 4.28Å; F589-W600 AromaticContact CE1-CZ2 3.94Å; F589-W600 HydrophobicContact CE1-CZ2 3.94Å; F589-W600 AromaticContact CZ-CH2 3.87Å; F589-W600 HydrophobicContact CZ-CH2 3.87Å; F589-W600 AromaticContact CZ-CZ2 3.66Å; F589-W600 HydrophobicContact CZ-CZ2 3.66Å; F589-F602 HydrophobicContact CB-CD1 4.07Å; F589-F602 HydrophobicContact CB-CG 4.37Å; F589-F602 HydrophobicContact CD1-CB 3.88Å; F589-F602 HydrophobicContact CD1-CD2 4.49Å; F589-F602 HydrophobicContact CD1-CG 4.12Å; F589-F602 HydrophobicContact CD2-CB 4.41Å; F589-F602 AromaticContact CD2-CD1 3.9Å; F589-F602 HydrophobicContact CD2-CD1 3.9Å; F589-F602 AromaticContact CD2-CD2 3.72Å; F589-F602 HydrophobicContact CD2-CD2 3.72Å; F589-F602 HydrophobicContact CD2-CE1 4.06Å; F589-F602 AromaticContact CD2-CE2 3.88Å; F589-F602 HydrophobicContact CD2-CE2 3.88Å; F589-F602 AromaticContact CD2-CG 3.74Å; F589-F602 HydrophobicContact CD2-CG 3.74Å; F589-F602 HydrophobicContact CD2-CZ 4.08Å; F589-F602 HydrophobicContact CE1-CB 4.08Å; F589-F602 HydrophobicContact CE1-CD2 4.3Å; F589-F602 HydrophobicContact CE1-CG 4.32Å; F589-F602 AromaticContact CE2-CD2 3.51Å; F589-F602 HydrophobicContact CE2-CD2 3.51Å; F589-F602 AromaticContact CE2-CE2 3.68Å; F589-F602 HydrophobicContact CE2-CE2 3.68Å; F589-F602 AromaticContact CE2-CG 3.98Å; F589-F602 HydrophobicContact CE2-CG 3.98Å; F589-F602 HydrophobicContact CE2-CZ 4.31Å; F589-F602 HydrophobicContact CG-CB 4.05Å; F589-F602 AromaticContact CG-CD1 3.98Å; F589-F602 HydrophobicContact CG-CD1 3.98Å; F589-F602 HydrophobicContact CG-CD2 4.23Å; F589-F602 AromaticContact CG-CG 3.83Å; F589-F602 HydrophobicContact CG-CG 3.83Å; F589-F602 HydrophobicContact CZ-CB 4.45Å; F589-F602 AromaticContact CZ-CD2 3.82Å; F589-F602 HydrophobicContact CZ-CD2 3.82Å; F589-F602 HydrophobicContact CZ-CE2 4.39Å; F589-F602 HydrophobicContact CZ-CG 4.26Å; F589-K825 HydrophobicContact CZ-CB 4.2Å
590E65.6Low64.6Low119 Ų11982.8 Ų82.856%0.55644%0.442SS*.Hα-helixtrans-84.6-23.6179.2-76.2-174.6150.300114.1K586 K592K586-E590 WeakPolarHBondContact CE-OE1 3.45Å; K586-E590 VanDerWaalsContact CE-OE2 3.3Å; K586-E590 WeakPolarHBondContact CE-OE2 3.49Å; K586-E590 HydrophobicContact CG-CG 3.97Å; K586-E590 IonicContact NZ-OE1 3.68Å; K586-E590 PolarHBondContact NZ-OE1 2.95Å; K586-E590 WeakPolarHBondContact O-CB 3.39Å; K586-E590 WeakPolarHBondContact O-CG 3.35Å; K586-E590 PolarHBondContact O-N 2.96Å; E590-K592 VanDerWaalsContact C-N 3.26Å; E590-K592 PolarHBondContact O-N 3.3Å
591T54.9Low65.1Low94 Ų9485.8 Ų85.858%0.57745%0.451SS*.SBendtrans-67.991169.918.40000108.3K587 A593K587-T591 PolarHBondContact O-N 3.17Å; K587-T591 PolarHBondContact O-OG1 3.27Å; T591-A593 VanDerWaalsContact C-N 3.31Å; T591-A593 PolarHBondContact O-N 3Å
592K42.4Very low65.5Low207 Ų20786.8 Ų86.890%0.946%0.456SS*.  trans-56.287.8177.1-68.5-178-179.8177.40110.2E590E590-K592 VanDerWaalsContact C-N 3.26Å; E590-K592 PolarHBondContact O-N 3.3Å
593A42.3Very low65.8Low49 Ų4985.2 Ų85.241%0.40545%0.452SS..  trans-94.2110.3164.700000107.6Y451 T591Y451-A593 HydrophobicContact CE1-CB 3.67Å; Y451-A593 HydrophobicContact CE2-CB 3.88Å; Y451-A593 WeakPolarHBondContact OH-CB 3.15Å; T591-A593 VanDerWaalsContact C-N 3.31Å; T591-A593 PolarHBondContact O-N 3Å
594D38.9Very low66.6Low97 Ų9784.4 Ų84.452%0.51944%0.44SS..SBendtrans69139171.7-141.5-7.6000114.9Q596D594-Q596 PolarHBondContact O-N 3.31Å
595G45.9Very low67.6Low80 Ų8080.7 Ų80.783%0.82542%0.423SS*.SBendtrans-62.99.6-171.200000116.5K597G595-K597 PolarHBondContact O-N 3.42Å
596Q46.4Very low68.3Low176 Ų17684.7 Ų84.782%0.82244%0.444SS*.  trans-75.9105.3175.1-82.1-173.5-10.100111.1D594 S598D594-Q596 PolarHBondContact O-N 3.31Å; Q596-S598 PolarHBondContact O-N 2.93Å
597K55.4Low68.9Low204 Ų20481.6 Ų81.689%0.88743%0.431SS*.  trans-54.2126.8167.3-75178.3178.1173.30109.3G595 S599G595-K597 PolarHBondContact O-N 3.42Å; K597-S599 PolarHBondContact O-N 3.3Å
598S68.3Low70Confident57 Ų5773.9 Ų73.940%0.39940%0.397SS..  trans-51.8137168.4176.90000110.3Q596 W600Q596-S598 PolarHBondContact O-N 2.93Å; S598-W600 VanDerWaalsContact CB-O 3.29Å; S598-W600 WeakPolarHBondContact CB-O 3.27Å; S598-W600 PolarHBondContact O-N 3.19Å; S598-W600 VanDerWaalsContact O-N 3.16Å; S598-W600 PolarHBondContact OG-N 2.89Å; S598-W600 PolarHBondContact OG-O 3.15Å
599S78.1Confident71Confident34 Ų3476.1 Ų76.124%0.23840%0.397CS..SBendtrans-63.2-16.1175.259.80000112.6K597 G820 V821 E846K597-S599 PolarHBondContact O-N 3.3Å; S599-G820 CarbonylContact O-C 3.4Å; S599-G820 VanDerWaalsContact O-CA 3.29Å; S599-G820 WeakPolarHBondContact O-CA 3.18Å; S599-V821 WeakPolarHBondContact CB-O 3.44Å; S599-V821 PolarHBondContact O-N 3.1Å; S599-V821 PolarHBondContact OG-O 3.26Å; S599-E846 WeakPolarHBondContact CB-OE2 3.21Å
600W85Confident71.5Confident7 Ų774.7 Ų74.73%0.02740%0.399CS..EExtended strand (participates in β ladder)trans-136.6154176.965-80.6000113.3F589 S598 F602 D813 Y817 S819 Y822 V823F589-W600 HydrophobicContact CE1-CH2 4.28Å; F589-W600 AromaticContact CE1-CZ2 3.94Å; F589-W600 HydrophobicContact CE1-CZ2 3.94Å; F589-W600 AromaticContact CZ-CH2 3.87Å; F589-W600 HydrophobicContact CZ-CH2 3.87Å; F589-W600 AromaticContact CZ-CZ2 3.66Å; F589-W600 HydrophobicContact CZ-CZ2 3.66Å; S598-W600 VanDerWaalsContact CB-O 3.29Å; S598-W600 WeakPolarHBondContact CB-O 3.27Å; S598-W600 PolarHBondContact O-N 3.19Å; S598-W600 VanDerWaalsContact O-N 3.16Å; S598-W600 PolarHBondContact OG-N 2.89Å; S598-W600 PolarHBondContact OG-O 3.15Å; W600-F602 HydrophobicContact CE3-CB 4.48Å; W600-F602 HydrophobicContact CH2-CB 4.34Å; W600-F602 AromaticContact CH2-CD2 3.69Å; W600-F602 HydrophobicContact CH2-CD2 3.69Å; W600-F602 HydrophobicContact CZ3-CB 3.96Å; W600-F602 AromaticContact CZ3-CD2 3.86Å; W600-F602 HydrophobicContact CZ3-CD2 3.86Å; W600-F602 HydrophobicContact CZ3-CG 4.42Å; W600-D813 HydrophobicContact CH2-CB 4.33Å; W600-Y817 HydrophobicContact CB-CD2 3.99Å; W600-Y817 HydrophobicContact CB-CE2 3.87Å; W600-Y817 HydrophobicContact CD2-CD2 4.17Å; W600-Y817 AromaticContact CE3-CD2 3.79Å; W600-Y817 HydrophobicContact CE3-CD2 3.79Å; W600-Y817 HydrophobicContact CE3-CG 4.47Å; W600-Y817 HydrophobicContact CG-CD2 4.29Å; W600-S819 CarbonylContact C-O 3.57Å; W600-S819 WeakPolarHBondContact CA-O 3.38Å; W600-S819 WeakPolarHBondContact CB-O 3.49Å; W600-Y822 HydrophobicContact CD2-CD2 4.15Å; W600-Y822 AromaticContact CE2-CD2 3.93Å; W600-Y822 HydrophobicContact CH2-CD2 4.43Å; W600-Y822 HydrophobicContact CH2-CE2 4.29Å; W600-Y822 HydrophobicContact CZ2-CD2 4.08Å; W600-Y822 AromaticContact CZ2-CE2 3.98Å; W600-Y822 HydrophobicContact CZ2-CE2 3.98Å; W600-V823 PolarHBondContact NE1-O 3.45Å
601K87.8Confident72.3Confident146 Ų14669.2 Ų69.264%0.63537%0.374SS*.EExtended strand (participates in β ladder)trans-88.7120.2176.8-61.4-172.5-171171.50110.6K818 S819K601-K818 HydrophobicContact CB-CB 4.13Å; K601-K818 VanDerWaalsContact O-CB 3.3Å; K601-K818 WeakPolarHBondContact O-CB 3.33Å; K601-K818 PolarHBondContact O-N 3.17Å; K601-S819 WeakPolarHBondContact CD-OG 3.4Å; K601-S819 WeakPolarHBondContact CG-OG 3.37Å; K601-S819 PolarHBondContact N-O 2.83Å
602F87.9Confident73.5Confident37 Ų3766.1 Ų66.116%0.16236%0.355CS..EExtended strand (participates in β ladder)trans-82.4135.9172.4179.7-100000110.7Y582 L585 K586 F589 W600 Y816Y582-F602 HydrophobicContact CD2-CD1 4.41Å; Y582-F602 AromaticContact CD2-CE1 3.46Å; Y582-F602 HydrophobicContact CD2-CE1 3.46Å; Y582-F602 VanDerWaalsContact CD2-CE1 3.46Å; Y582-F602 AromaticContact CD2-CZ 3.58Å; Y582-F602 HydrophobicContact CD2-CZ 3.58Å; Y582-F602 AromaticContact CE2-CD1 3.8Å; Y582-F602 HydrophobicContact CE2-CD1 3.8Å; Y582-F602 AromaticContact CE2-CE1 3.23Å; Y582-F602 HydrophobicContact CE2-CE1 3.23Å; Y582-F602 AromaticContact CE2-CZ 3.83Å; Y582-F602 HydrophobicContact CE2-CZ 3.83Å; L585-F602 HydrophobicContact CB-CE1 4.25Å; L585-F602 HydrophobicContact CB-CE2 4.02Å; L585-F602 HydrophobicContact CB-CZ 3.45Å; L585-F602 VanDerWaalsContact CB-CZ 3.45Å; L585-F602 HydrophobicContact CD1-CE2 4.04Å; L585-F602 HydrophobicContact CD1-CZ 4.15Å; L585-F602 HydrophobicContact CG-CZ 4.48Å; K586-F602 HydrophobicContact CB-CE1 4.15Å; F589-F602 HydrophobicContact CB-CD1 4.07Å; F589-F602 HydrophobicContact CB-CG 4.37Å; F589-F602 HydrophobicContact CD1-CB 3.88Å; F589-F602 HydrophobicContact CD1-CD2 4.49Å; F589-F602 HydrophobicContact CD1-CG 4.12Å; F589-F602 HydrophobicContact CD2-CB 4.41Å; F589-F602 AromaticContact CD2-CD1 3.9Å; F589-F602 HydrophobicContact CD2-CD1 3.9Å; F589-F602 AromaticContact CD2-CD2 3.72Å; F589-F602 HydrophobicContact CD2-CD2 3.72Å; F589-F602 HydrophobicContact CD2-CE1 4.06Å; F589-F602 AromaticContact CD2-CE2 3.88Å; F589-F602 HydrophobicContact CD2-CE2 3.88Å; F589-F602 AromaticContact CD2-CG 3.74Å; F589-F602 HydrophobicContact CD2-CG 3.74Å; F589-F602 HydrophobicContact CD2-CZ 4.08Å; F589-F602 HydrophobicContact CE1-CB 4.08Å; F589-F602 HydrophobicContact CE1-CD2 4.3Å; F589-F602 HydrophobicContact CE1-CG 4.32Å; F589-F602 AromaticContact CE2-CD2 3.51Å; F589-F602 HydrophobicContact CE2-CD2 3.51Å; F589-F602 AromaticContact CE2-CE2 3.68Å; F589-F602 HydrophobicContact CE2-CE2 3.68Å; F589-F602 AromaticContact CE2-CG 3.98Å; F589-F602 HydrophobicContact CE2-CG 3.98Å; F589-F602 HydrophobicContact CE2-CZ 4.31Å; F589-F602 HydrophobicContact CG-CB 4.05Å; F589-F602 AromaticContact CG-CD1 3.98Å; F589-F602 HydrophobicContact CG-CD1 3.98Å; F589-F602 HydrophobicContact CG-CD2 4.23Å; F589-F602 AromaticContact CG-CG 3.83Å; F589-F602 HydrophobicContact CG-CG 3.83Å; F589-F602 HydrophobicContact CZ-CB 4.45Å; F589-F602 AromaticContact CZ-CD2 3.82Å; F589-F602 HydrophobicContact CZ-CD2 3.82Å; F589-F602 HydrophobicContact CZ-CE2 4.39Å; F589-F602 HydrophobicContact CZ-CG 4.26Å; W600-F602 HydrophobicContact CE3-CB 4.48Å; W600-F602 HydrophobicContact CH2-CB 4.34Å; W600-F602 AromaticContact CH2-CD2 3.69Å; W600-F602 HydrophobicContact CH2-CD2 3.69Å; W600-F602 HydrophobicContact CZ3-CB 3.96Å; W600-F602 AromaticContact CZ3-CD2 3.86Å; W600-F602 HydrophobicContact CZ3-CD2 3.86Å; W600-F602 HydrophobicContact CZ3-CG 4.42Å; F602-Y816 HydrophobicContact CD2-CG 4.33Å; F602-Y816 HydrophobicContact CE2-CD1 4.42Å; F602-Y816 AromaticContact CE2-CD2 3.69Å; F602-Y816 HydrophobicContact CE2-CD2 3.69Å; F602-Y816 AromaticContact CE2-CG 3.52Å; F602-Y816 HydrophobicContact CE2-CG 3.52Å; F602-Y816 HydrophobicContact CZ-CD1 4.35Å; F602-Y816 HydrophobicContact CZ-CD2 4.14Å; F602-Y816 AromaticContact CZ-CG 3.85Å; F602-Y816 HydrophobicContact CZ-CG 3.85Å
603G89.8Confident75.1Confident8 Ų858.3 Ų58.38%0.08232%0.322CS..  trans178.9167.7-178.800000114.5Y816G603-Y816 PolarHBondContact N-O 2.84Å; G603-Y816 CarbonylContact O-C 3.53Å; G603-Y816 WeakPolarHBondContact O-CA 3.4Å; G603-Y816 WeakPolarHBondContact O-CB 3.31Å
604L90.5Very high76.7Confident35 Ų3559.6 Ų59.618%0.18332%0.322CS..  trans-73.2140.7175.9-71.5151000111.8Y578 Y582 R609 Y816 K818Y578-L604 HydrophobicContact CD1-CD2 3.89Å; Y578-L604 HydrophobicContact CE1-CD2 3.36Å; Y582-L604 HydrophobicContact CD1-CD1 3.33Å; Y582-L604 HydrophobicContact CD1-CD2 3.93Å; Y582-L604 HydrophobicContact CD1-CG 3.6Å; Y582-L604 HydrophobicContact CD2-CD1 4.34Å; Y582-L604 HydrophobicContact CD2-CD2 3.96Å; Y582-L604 HydrophobicContact CD2-CG 3.69Å; Y582-L604 HydrophobicContact CE1-CD1 3.32Å; Y582-L604 HydrophobicContact CE1-CG 3.76Å; Y582-L604 HydrophobicContact CE2-CD1 4.34Å; Y582-L604 HydrophobicContact CE2-CG 3.86Å; Y582-L604 HydrophobicContact CG-CD1 3.85Å; Y582-L604 HydrophobicContact CG-CD2 3.55Å; Y582-L604 HydrophobicContact CG-CG 3.54Å; L604-R609 VanDerWaalsContact CB-NH2 3.35Å; L604-R609 VanDerWaalsContact CD1-NH1 3.3Å; L604-Y816 HydrophobicContact CD2-CE1 4.34Å; L604-K818 WeakPolarHBondContact O-CD 3.41Å; L604-K818 PolarHBondContact O-NZ 3.01Å
605N91.1Very high78.8Confident0 Ų057.1 Ų57.10%031%0.307CS..  trans-113.8131.2175.8-74.9-61.8000110.1Y578 R607 F608 Y815 Y817 K818 W859 G860Y578-N605 PolarHBondContact OH-N 3.46Å; N605-R607 PolarHBondContact O-N 3.08Å; N605-F608 HydrophobicContact CB-CD2 4.21Å; N605-F608 PolarHBondContact O-N 3.17Å; N605-F608 VanDerWaalsContact O-N 3.12Å; N605-Y815 PolarHBondContact ND2-O 3.22Å; N605-Y817 PolarHBondContact ND2-O 2.86Å; N605-K818 VanDerWaalsContact OD1-CD 3.26Å; N605-K818 WeakPolarHBondContact OD1-CD 2.86Å; N605-K818 PolarHBondContact OD1-NZ 2.94Å; N605-W859 VanDerWaalsContact ND2-CD1 3.33Å; N605-G860 PolarHBondContact OD1-N 2.86Å
606D88.9Confident80.7Confident94 Ų9453.3 Ų53.350%0.50327%0.268SS..G310 helixtrans-61.8-21.7-178.6-64.9-26.9000112.8F608 R609 R858D606-F608 PolarHBondContact O-N 3.4Å; D606-R609 IonicContact OD1-NE 2.87Å; D606-R858 HydrophobicContact CB-CB 4.39Å
607R88.6Confident82.5Confident10 Ų1046.8 Ų46.84%0.03824%0.237CC..G310 helixtrans-57.4-34.4175.3178.359.3-172.992.5-3.8113.6N605 M611 S669 W855 R858 W859N605-R607 PolarHBondContact O-N 3.08Å; R607-M611 PolarHBondContact NH1-SD 2.94Å; R607-M611 VanDerWaalsContact NH1-SD 3.42Å; R607-S669 PolarHBondContact NH2-O 3Å; R607-W855 WeakPolarHBondContact CD-O 3.42Å; R607-W855 HydrophobicContact CG-CB 4.37Å; R607-R858 HydrophobicContact CB-CB 4.44Å; R607-W859 HydrophobicContact CB-CB 4.14Å
608F89.2Confident84Confident0 Ų040.4 Ų40.40%021%0.207CC..G310 helixtrans-110.32.7-170.1-58.9-55.8000114.4Y578 N605 D606 G610 M611 M616 L619 Y815 W855 W859Y578-F608 WeakPolarHBondContact CB-O 2.91Å; Y578-F608 HydrophobicContact CD1-CB 3.71Å; Y578-F608 VanDerWaalsContact CD1-O 3.23Å; Y578-F608 WeakPolarHBondContact CD1-O 3.03Å; Y578-F608 HydrophobicContact CD2-CB 3.6Å; Y578-F608 HydrophobicContact CD2-CG 4.37Å; Y578-F608 HydrophobicContact CE1-CB 3.62Å; Y578-F608 HydrophobicContact CE2-CB 3.52Å; Y578-F608 AromaticContact CE2-CD2 3.86Å; Y578-F608 HydrophobicContact CE2-CD2 3.86Å; Y578-F608 HydrophobicContact CE2-CG 4.05Å; Y578-F608 HydrophobicContact CG-CB 3.69Å; N605-F608 HydrophobicContact CB-CD2 4.21Å; N605-F608 PolarHBondContact O-N 3.17Å; N605-F608 VanDerWaalsContact O-N 3.12Å; D606-F608 PolarHBondContact O-N 3.4Å; F608-G610 PolarHBondContact O-N 2.74Å; F608-M611 HydrophobicContact CB-SD 4.46Å; F608-M611 HydrophobicContact CD1-SD 3.77Å; F608-M611 VanDerWaalsContact O-CB 3.31Å; F608-M611 WeakPolarHBondContact O-CB 3.19Å; F608-M611 PolarHBondContact O-N 2.67Å; F608-M616 HydrophobicContact CB-SD 4.07Å; F608-M616 HydrophobicContact CD1-CG 3.92Å; F608-M616 HydrophobicContact CD1-SD 4.11Å; F608-M616 HydrophobicContact CG-CG 4.49Å; F608-M616 HydrophobicContact CG-SD 4.1Å; F608-L619 HydrophobicContact CE1-CD1 3.75Å; F608-Y815 HydrophobicContact CD2-CD1 4.33Å; F608-Y815 WeakPolarHBondContact CD2-O 3.22Å; F608-Y815 HydrophobicContact CE1-CD1 4.1Å; F608-Y815 HydrophobicContact CE1-CE1 4.5Å; F608-Y815 AromaticContact CE2-CD1 3.73Å; F608-Y815 HydrophobicContact CE2-CD1 3.73Å; F608-Y815 HydrophobicContact CE2-CG 4.27Å; F608-Y815 AromaticContact CZ-CD1 3.61Å; F608-Y815 HydrophobicContact CZ-CD1 3.61Å; F608-Y815 HydrophobicContact CZ-CE1 4.29Å; F608-W855 HydrophobicContact CE1-CE3 4.48Å; F608-W855 HydrophobicContact CE2-CE3 4.01Å; F608-W855 AromaticContact CE2-CZ3 3.98Å; F608-W855 HydrophobicContact CE2-CZ3 3.98Å; F608-W855 AromaticContact CZ-CD2 3.83Å; F608-W855 HydrophobicContact CZ-CD2 3.83Å; F608-W855 AromaticContact CZ-CE3 3.41Å; F608-W855 HydrophobicContact CZ-CE3 3.41Å; F608-W855 VanDerWaalsContact CZ-CE3 3.41Å; F608-W855 HydrophobicContact CZ-CH2 4.04Å; F608-W855 HydrophobicContact CZ-CZ2 4.44Å; F608-W855 AromaticContact CZ-CZ3 3.53Å; F608-W855 HydrophobicContact CZ-CZ3 3.53Å; F608-W859 AromaticContact CE2-CD1 3.31Å; F608-W859 HydrophobicContact CE2-CG 4.25Å; F608-W859 AromaticContact CE2-NE1 3.72Å
609R86.2Confident85.1Confident85 Ų8537.7 Ų37.732%0.32119%0.188SC..THydrogen-bonded Turntrans-55.1120.9-176.6-70-66.9-165.7172.85.2112.7E579 L604 D606 M611 R754E579-R609 VanDerWaalsContact OE1-CA 3.25Å; E579-R609 WeakPolarHBondContact OE1-CA 3.25Å; E579-R609 WeakPolarHBondContact OE1-CD 3.1Å; E579-R609 IonicContact OE1-NH1 3.83Å; L604-R609 VanDerWaalsContact CB-NH2 3.35Å; L604-R609 VanDerWaalsContact CD1-NH1 3.3Å; D606-R609 IonicContact OD1-NE 2.87Å; R609-M611 PolarHBondContact O-N 2.93Å; R609-R754 VanDerWaalsContact O-CZ 3.26Å; R609-R754 PolarHBondContact O-NH1 3.36Å; R609-R754 PolarHBondContact O-NH2 3.29Å
610G78.4Confident85.7Confident29 Ų2936.9 Ų36.930%0.29918%0.181SC..THydrogen-bonded Turntrans62.823.4-178.100000114.4A575 E579 F608A575-G610 CarbonylContact O-C 3.47Å; E579-G610 PolarHBondContact OE1-N 3.18Å; E579-G610 WeakPolarHBondContact OE2-CA 3.39Å; E579-G610 PolarHBondContact OE2-N 3.11Å; F608-G610 PolarHBondContact O-N 2.74Å
611M82.7Confident86Confident5 Ų536.8 Ų36.83%0.02518%0.183CC..  trans-84.5137.5169.4-70.7-177.166.900109.9Y578 R607 F608 R609 E615 M616 L619Y578-M611 PolarHBondContact N-O 3.41Å; R607-M611 PolarHBondContact NH1-SD 2.94Å; R607-M611 VanDerWaalsContact NH1-SD 3.42Å; F608-M611 HydrophobicContact CB-SD 4.46Å; F608-M611 HydrophobicContact CD1-SD 3.77Å; F608-M611 VanDerWaalsContact O-CB 3.31Å; F608-M611 WeakPolarHBondContact O-CB 3.19Å; F608-M611 PolarHBondContact O-N 2.67Å; R609-M611 PolarHBondContact O-N 2.93Å; M611-E615 HydrophobicContact CB-CB 4.3Å; M611-E615 VanDerWaalsContact CE-C 3.45Å; M611-E615 HydrophobicContact CE-CB 3.53Å; M611-E615 WeakPolarHBondContact CE-O 3.39Å; M611-M616 HydrophobicContact CB-CG 3.9Å; M611-M616 HydrophobicContact CE-CG 4.18Å; M611-M616 HydrophobicContact SD-CG 4.5Å; M611-L619 HydrophobicContact CE-CD1 4.36Å
612S78.8Confident85.9Confident28 Ų2830.4 Ų30.420%0.19616%0.156CC..  trans-70.4161.3167.160.80000111.6D614 E615 M616S612-D614 VanDerWaalsContact C-N 3.27Å; S612-D614 PolarHBondContact O-N 3.49Å; S612-E615 WeakPolarHBondContact CB-OE2 3.39Å; S612-E615 PolarHBondContact N-OE2 3.11Å; S612-E615 PolarHBondContact O-N 3.49Å; S612-E615 VanDerWaalsContact O-N 3.16Å; S612-E615 VanDerWaalsContact OG-CD 3.32Å; S612-E615 WeakPolarHBondContact OG-CG 3.19Å; S612-E615 PolarHBondContact OG-N 3.23Å; S612-E615 PolarHBondContact OG-OE2 3.18Å; S612-M616 PolarHBondContact O-N 2.86Å; S612-M616 VanDerWaalsContact O-N 3.11Å
613F77.4Confident85.3Confident44 Ų4429.6 Ų29.619%0.19315%0.154CC..Hα-helixtrans-54.2-43.7174.5-178.1-109.5000112.4D310 Y577 E615 M616 K617 I830D310-F613 HydrophobicContact CB-CE1 4.09Å; Y577-F613 HydrophobicContact CD1-CB 3.79Å; Y577-F613 HydrophobicContact CD1-CD2 4.17Å; Y577-F613 HydrophobicContact CD1-CG 4.49Å; Y577-F613 HydrophobicContact CD2-CB 4Å; Y577-F613 HydrophobicContact CE1-CB 3.98Å; Y577-F613 AromaticContact CE1-CD2 3.47Å; Y577-F613 HydrophobicContact CE1-CD2 3.47Å; Y577-F613 VanDerWaalsContact CE1-CD2 3.47Å; Y577-F613 HydrophobicContact CE1-CE2 4.4Å; Y577-F613 HydrophobicContact CE1-CG 4.19Å; Y577-F613 HydrophobicContact CE2-CB 4.16Å; Y577-F613 HydrophobicContact CE2-CD2 4.04Å; Y577-F613 HydrophobicContact CE2-CG 4.35Å; Y577-F613 HydrophobicContact CG-CB 3.8Å; Y577-F613 AromaticContact CZ-CD2 3.38Å; Y577-F613 WeakPolarHBondContact OH-CD2 3.5Å; F613-E615 VanDerWaalsContact C-N 3.34Å; F613-E615 PolarHBondContact O-N 2.91Å; F613-M616 PolarHBondContact O-N 3.34Å; F613-K617 HydrophobicContact CE1-CD 4.04Å; F613-K617 HydrophobicContact CZ-CD 4.35Å; F613-K617 WeakPolarHBondContact O-CB 3.26Å; F613-K617 PolarHBondContact O-N 2.81Å; F613-I830 HydrophobicContact CE2-CD1 3.72Å; F613-I830 HydrophobicContact CE2-CG1 4.1Å; F613-I830 HydrophobicContact CE2-CG2 4.02Å; F613-I830 HydrophobicContact CZ-CD1 4.42Å; F613-I830 HydrophobicContact CZ-CG1 4.33Å; F613-I830 HydrophobicContact CZ-CG2 3.89Å
614D74.6Confident84.1Confident76 Ų7633 Ų3341%0.40617%0.167SC..Hα-helixtrans-62.3-38.7178.8-77.9-3.7000112.6S612 R618S612-D614 VanDerWaalsContact C-N 3.27Å; S612-D614 PolarHBondContact O-N 3.49Å; D614-R618 WeakPolarHBondContact O-CB 3.18Å; D614-R618 PolarHBondContact O-N 3.44Å; D614-R618 VanDerWaalsContact O-N 3.07Å
615E83.3Confident82.2Confident45 Ų4538.3 Ų38.321%0.2120%0.196CC..Hα-helixtrans-68.9-39177.1-70.9169.9122.600111.7M611 S612 F613M611-E615 HydrophobicContact CB-CB 4.3Å; M611-E615 VanDerWaalsContact CE-C 3.45Å; M611-E615 HydrophobicContact CE-CB 3.53Å; M611-E615 WeakPolarHBondContact CE-O 3.39Å; S612-E615 WeakPolarHBondContact CB-OE2 3.39Å; S612-E615 PolarHBondContact N-OE2 3.11Å; S612-E615 PolarHBondContact O-N 3.49Å; S612-E615 VanDerWaalsContact O-N 3.16Å; S612-E615 VanDerWaalsContact OG-CD 3.32Å; S612-E615 WeakPolarHBondContact OG-CG 3.19Å; S612-E615 PolarHBondContact OG-N 3.23Å; S612-E615 PolarHBondContact OG-OE2 3.18Å; F613-E615 VanDerWaalsContact C-N 3.34Å; F613-E615 PolarHBondContact O-N 2.91Å
616M85.9Confident79.8Confident0 Ų041.2 Ų41.20%021%0.211CC..Hα-helixtrans-68.1-46.7175.7-68.7-168.4-70.800111.9Y577 Y578 F608 M611 S612 F613 R618 L619 Y815Y577-M616 HydrophobicContact CD1-CE 3.27Å; Y577-M616 HydrophobicContact CE1-CE 3.44Å; Y577-M616 VanDerWaalsContact CE1-CE 3.44Å; Y578-M616 HydrophobicContact CD2-CE 4.15Å; Y578-M616 HydrophobicContact CD2-SD 3.54Å; Y578-M616 VanDerWaalsContact CD2-SD 3.54Å; Y578-M616 HydrophobicContact CE2-SD 4.31Å; Y578-M616 HydrophobicContact CG-SD 4.2Å; F608-M616 HydrophobicContact CB-SD 4.07Å; F608-M616 HydrophobicContact CD1-CG 3.92Å; F608-M616 HydrophobicContact CD1-SD 4.11Å; F608-M616 HydrophobicContact CG-CG 4.49Å; F608-M616 HydrophobicContact CG-SD 4.1Å; M611-M616 HydrophobicContact CB-CG 3.9Å; M611-M616 HydrophobicContact CE-CG 4.18Å; M611-M616 HydrophobicContact SD-CG 4.5Å; S612-M616 PolarHBondContact O-N 2.86Å; S612-M616 VanDerWaalsContact O-N 3.11Å; F613-M616 PolarHBondContact O-N 3.34Å; M616-R618 VanDerWaalsContact C-N 3.26Å; M616-R618 PolarHBondContact O-N 3.19Å; M616-L619 WeakPolarHBondContact O-CB 3.47Å; M616-L619 WeakPolarHBondContact O-CG 2.86Å; M616-L619 PolarHBondContact O-N 3.45Å; M616-L619 VanDerWaalsContact O-N 3.1Å; M616-Y815 HydrophobicContact CB-CE1 3.97Å; M616-Y815 HydrophobicContact CB-CE2 4.14Å; M616-Y815 HydrophobicContact CE-CD2 4.39Å; M616-Y815 HydrophobicContact CE-CE2 4.4Å; M616-Y815 HydrophobicContact SD-CD1 4.27Å; M616-Y815 HydrophobicContact SD-CD2 3.97Å; M616-Y815 HydrophobicContact SD-CE2 4.19Å; M616-Y815 HydrophobicContact SD-CG 4Å
617K84.3Confident77.4Confident38 Ų3841.4 Ų41.417%0.16521%0.212CC..Hα-helixtrans-62.5-32.3179.2-177.3168.1177-176.80112.6D310 F613 L619 L620 I830D310-K617 WeakPolarHBondContact OD2-CD 3.32Å; D310-K617 VanDerWaalsContact OD2-CE 3.23Å; D310-K617 WeakPolarHBondContact OD2-CE 3.42Å; D310-K617 IonicContact OD2-NZ 3.79Å; D310-K617 PolarHBondContact OD2-NZ 3.24Å; F613-K617 HydrophobicContact CE1-CD 4.04Å; F613-K617 HydrophobicContact CZ-CD 4.35Å; F613-K617 WeakPolarHBondContact O-CB 3.26Å; F613-K617 PolarHBondContact O-N 2.81Å; K617-L619 PolarHBondContact O-N 3.45Å; K617-L619 VanDerWaalsContact O-N 3.1Å; K617-L620 WeakPolarHBondContact O-CB 3.43Å; K617-L620 PolarHBondContact O-N 3.19Å; K617-I830 HydrophobicContact CB-CG2 3.98Å; K617-I830 HydrophobicContact CD-CG2 3.86Å; K617-I830 VanDerWaalsContact CE-O 3.28Å; K617-I830 WeakPolarHBondContact CE-O 3.24Å; K617-I830 HydrophobicContact CG-CG2 3.8Å
618R86.6Confident74.6Confident70 Ų7048 Ų4826%0.26424%0.243SC..THydrogen-bonded Turntrans-58.3-23.4175.9-155.8-173.5-51.7-73.6-3.3113.3D614 M616 L620 G672 K756D614-R618 WeakPolarHBondContact O-CB 3.18Å; D614-R618 PolarHBondContact O-N 3.44Å; D614-R618 VanDerWaalsContact O-N 3.07Å; M616-R618 VanDerWaalsContact C-N 3.26Å; M616-R618 PolarHBondContact O-N 3.19Å; R618-L620 PolarHBondContact O-N 3.2Å; R618-G672 WeakPolarHBondContact O-CA 3.47Å; R618-G672 PolarHBondContact O-N 3.41Å; R618-K756 VanDerWaalsContact NH1-CE 3.3Å
619L92.3Very high71.9Confident0 Ų054.6 Ų54.60%029%0.286CS..THydrogen-bonded Turntrans-74.4-15.6177.5-53.2-179.5000112.8F608 M611 M616 K617 G621 Q668 S669 H833F608-L619 HydrophobicContact CE1-CD1 3.75Å; M611-L619 HydrophobicContact CE-CD1 4.36Å; M616-L619 WeakPolarHBondContact O-CB 3.47Å; M616-L619 WeakPolarHBondContact O-CG 2.86Å; M616-L619 PolarHBondContact O-N 3.45Å; M616-L619 VanDerWaalsContact O-N 3.1Å; K617-L619 PolarHBondContact O-N 3.45Å; K617-L619 VanDerWaalsContact O-N 3.1Å; L619-G621 VanDerWaalsContact C-N 3.3Å; L619-G621 PolarHBondContact O-N 3.2Å; L619-G621 VanDerWaalsContact O-N 3.14Å; L619-Q668 HydrophobicContact CD2-CG 4.37Å; L619-Q668 PolarHBondContact O-NE2 2.85Å; L619-S669 WeakPolarHBondContact CD2-O 3.39Å; L619-H833 PolarHBondContact O-ND1 2.67Å
620L91.4Very high69.3Low17 Ų1753 Ų539%0.08929%0.287CS..  trans-89.165-179.8-47.4-176.6000110.3K617 R618 V622 V810 I830 N832 H833 W855K617-L620 WeakPolarHBondContact O-CB 3.43Å; K617-L620 PolarHBondContact O-N 3.19Å; R618-L620 PolarHBondContact O-N 3.2Å; L620-V622 VanDerWaalsContact C-N 3.28Å; L620-V622 PolarHBondContact O-N 2.86Å; L620-V810 HydrophobicContact CD1-CB 4.01Å; L620-V810 HydrophobicContact CD1-CG1 4.07Å; L620-V810 HydrophobicContact CD2-CB 4.03Å; L620-V810 HydrophobicContact CD2-CG1 4.03Å; L620-V810 HydrophobicContact CD2-CG2 3.89Å; L620-I830 HydrophobicContact CD1-CB 4.01Å; L620-I830 HydrophobicContact CD1-CG2 3.7Å; L620-N832 CarbonylContact C-O 3.56Å; L620-H833 HydrophobicContact CD2-CB 3.97Å; L620-W855 HydrophobicContact CD2-CZ2 3.92Å
621G90.4Very high67Low6 Ų659.6 Ų59.66%0.06232%0.316CS..  trans-78.912.7-168.400000116.9L619 S623 G672 C674 G717 G718L619-G621 VanDerWaalsContact C-N 3.3Å; L619-G621 PolarHBondContact O-N 3.2Å; L619-G621 VanDerWaalsContact O-N 3.14Å; G621-S623 PolarHBondContact O-N 3.3Å; G621-G672 WeakPolarHBondContact CA-O 3.35Å; G621-C674 PolarHBondContact N-SG 2.95Å; G621-G717 CarbonylContact O-C 3.56Å; G621-G717 WeakPolarHBondContact O-CA 3.25Å; G621-G718 PolarHBondContact O-N 2.61Å
622V85.5Confident64.8Low12 Ų1266.3 Ų66.37%0.07335%0.346CS..BIsolated β-bridgetrans-80.5120177.1179.20000109.7L620 F624 G718 I807 N832 A834L620-V622 VanDerWaalsContact C-N 3.28Å; L620-V622 PolarHBondContact O-N 2.86Å; V622-F624 HydrophobicContact CG1-CE1 4.39Å; V622-F624 HydrophobicContact CG1-CE2 4.39Å; V622-F624 HydrophobicContact CG1-CZ 4.13Å; V622-G718 WeakPolarHBondContact CA-O 3.46Å; V622-I807 HydrophobicContact CB-CG2 4.45Å; V622-I807 HydrophobicContact CG1-CD1 4.08Å; V622-I807 HydrophobicContact CG1-CG1 4.43Å; V622-I807 HydrophobicContact CG1-CG2 3.89Å; V622-I807 HydrophobicContact CG2-CG2 4.35Å; V622-N832 HydrophobicContact CB-CB 3.99Å; V622-N832 HydrophobicContact CG1-CB 4.26Å; V622-N832 PolarHBondContact N-O 3.05Å; V622-A834 HydrophobicContact CG2-CB 3.58Å
623S75.2Confident62.6Low19 Ų1971.4 Ų71.413%0.13338%0.375CS..  trans-116136.9172.9166.50000110.4G621 D625 G718G621-S623 PolarHBondContact O-N 3.3Å; S623-D625 PolarHBondContact OG-N 2.77Å; S623-D625 PolarHBondContact OG-OD2 3.05Å; S623-G718 PolarHBondContact N-O 2.85Å
624F65.8Low61.2Low80 Ų8072.4 Ų72.435%0.35138%0.381SS..  trans-99-5.8173.4-63.3-69.1000112.5V622 N626 L627 I807 N832V622-F624 HydrophobicContact CG1-CE1 4.39Å; V622-F624 HydrophobicContact CG1-CE2 4.39Å; V622-F624 HydrophobicContact CG1-CZ 4.13Å; F624-N626 PolarHBondContact O-N 3.22Å; F624-N626 VanDerWaalsContact O-N 3.13Å; F624-L627 PolarHBondContact O-N 3.17Å; F624-I807 HydrophobicContact CE1-CD1 4.43Å; F624-I807 HydrophobicContact CZ-CG2 4.04Å; F624-N832 HydrophobicContact CE2-CB 4.26Å; F624-N832 WeakPolarHBondContact CE2-ND2 3.44Å
625D49.9Very low59.9Low147 Ų14772.5 Ų72.579%0.78638%0.379SS*.THydrogen-bonded Turntrans-67.9-16.1-172.5-47.5-53.4000113.3S623S623-D625 PolarHBondContact OG-N 2.77Å; S623-D625 PolarHBondContact OG-OD2 3.05Å
626N40.5Very low58.5Low60 Ų6073.5 Ų73.532%0.32139%0.386SS..THydrogen-bonded Turntrans-97.812.2-179.7-59.9-51.2000113.8F624 E628F624-N626 PolarHBondContact O-N 3.22Å; F624-N626 VanDerWaalsContact O-N 3.13Å; N626-E628 PolarHBondContact O-N 2.97Å
627L38Very low57Low99 Ų9974.5 Ų74.552%0.51839%0.392SS..  trans-74.587.8163.7-66.1172.3000106.7F624F624-L627 PolarHBondContact O-N 3.17Å
628E31.3Very low55.6Low148 Ų14877 Ų7769%0.69241%0.407SS*.  trans-51.3134.3153.6-72.2-160.4162.500106.4N626 S630N626-E628 PolarHBondContact O-N 2.97Å; E628-S630 PolarHBondContact O-N 3.01Å; E628-S630 PolarHBondContact O-OG 2.76Å
629P31.4Very low54Low138 Ų13877.3 Ų77.390%0.89641%0.409SS*.  trans-69.663.4161.131.3-30.9000107.1
630S31.1Very low51.9Low51 Ų5183.2 Ų83.236%0.35745%0.45SS..  trans-84.3138.4168.451.30000105E628 F632E628-S630 PolarHBondContact O-N 3.01Å; E628-S630 PolarHBondContact O-OG 2.76Å; S630-F632 PolarHBondContact O-N 3.02Å; S630-F632 WeakPolarHBondContact OG-CD2 3.48Å
631N29.8Very low49.8Very low169 Ų16988.6 Ų88.690%0.90448%0.478SS*.SBendtrans-55.727.6-177.7-71.6-20.4000116.1T633N631-T633 PolarHBondContact O-N 3.39Å; N631-T633 VanDerWaalsContact O-N 3.12Å
632F37.1Very low47.9Very low146 Ų14695.9 Ų95.964%0.6452%0.515SS*.  trans-79.289.1172.3-75.8-82000109.4S630 M634S630-F632 PolarHBondContact O-N 3.02Å; S630-F632 WeakPolarHBondContact OG-CD2 3.48Å; F632-M634 PolarHBondContact O-N 3.2Å; F632-M634 VanDerWaalsContact O-N 3.08Å
633T33.9Very low46.7Very low134 Ų134100.6 Ų100.682%0.82254%0.537SS*.  trans-59.6111.7158.844.30000107.9N631 E635N631-T633 PolarHBondContact O-N 3.39Å; N631-T633 VanDerWaalsContact O-N 3.12Å; T633-E635 PolarHBondContact O-N 3.28Å
634M47.5Very low46.7Very low65 Ų65108 Ų10832%0.3258%0.575SS.*  trans-67.9123.5173.3179.3167.960.500107.4F632 I636 F721 G786F632-M634 PolarHBondContact O-N 3.2Å; F632-M634 VanDerWaalsContact O-N 3.08Å; M634-I636 HydrophobicContact CE-CD1 3.94Å; M634-I636 HydrophobicContact CE-CG1 3.82Å; M634-I636 HydrophobicContact CG-CG1 4.22Å; M634-I636 PolarHBondContact O-N 3.07Å; M634-F721 HydrophobicContact CG-CE2 3.97Å; M634-F721 HydrophobicContact CG-CZ 4.36Å; M634-F721 HydrophobicContact SD-CD2 4.01Å; M634-F721 HydrophobicContact SD-CE2 3.84Å; M634-F721 HydrophobicContact SD-CZ 4.5Å; M634-G786 VanDerWaalsContact SD-CA 3.56Å
635E46.5Very low47.6Very low78 Ų78105.6 Ų105.636%0.36457%0.566SS.*  trans-63113.6166.7-162.9-153122.400107.7T633 R783 Y785 G786T633-E635 PolarHBondContact O-N 3.28Å; E635-R783 IonicContact OE1-CZ 3.2Å; E635-R783 IonicContact OE1-NE 3.16Å; E635-R783 PolarHBondContact OE1-NE 3.15Å; E635-R783 VanDerWaalsContact OE1-NE 3.12Å; E635-R783 IonicContact OE1-NH2 3.61Å; E635-R783 PolarHBondContact OE1-NH2 3.37Å; E635-R783 IonicContact OE2-CZ 3.31Å; E635-R783 IonicContact OE2-NE 2.71Å; E635-R783 PolarHBondContact OE2-NE 3.24Å; E635-R783 IonicContact OE2-NH2 2.84Å; E635-R783 PolarHBondContact OE2-NH2 3.07Å; E635-R783 VanDerWaalsContact OE2-NH2 3.08Å; E635-Y785 CarbonylContact O-C 3.37Å; E635-Y785 WeakPolarHBondContact O-CA 3.48Å; E635-Y785 WeakPolarHBondContact O-CB 3.44Å; E635-G786 PolarHBondContact O-N 3.11Å
636I53.5Low49.6Very low66 Ų66101.4 Ų101.434%0.33855%0.546SS..EExtended strand (participates in β ladder)trans-104.7117.6176.2-66.5176000106.7M634 G786 R788M634-I636 HydrophobicContact CE-CD1 3.94Å; M634-I636 HydrophobicContact CE-CG1 3.82Å; M634-I636 HydrophobicContact CG-CG1 4.22Å; M634-I636 PolarHBondContact O-N 3.07Å; I636-G786 WeakPolarHBondContact CA-O 3.5Å; I636-R788 HydrophobicContact CG2-CB 3.48Å; I636-R788 VanDerWaalsContact CG2-CB 3.48Å; I636-R788 HydrophobicContact CG2-CG 4.16Å
637V55.9Low51.9Low22 Ų22105.3 Ų105.313%0.13356%0.563CS.*EExtended strand (participates in β ladder)trans-84.2125.4174.9-138.30000108.5Y639 Y785 G786V637-Y639 HydrophobicContact CB-CE2 3.97Å; V637-Y639 HydrophobicContact CG1-CD2 4.49Å; V637-Y639 HydrophobicContact CG1-CE1 4.48Å; V637-Y639 HydrophobicContact CG1-CE2 3.67Å; V637-Y785 HydrophobicContact CG2-CD1 4.32Å; V637-Y785 HydrophobicContact CG2-CD2 3.15Å; V637-Y785 HydrophobicContact CG2-CE2 3.54Å; V637-Y785 HydrophobicContact CG2-CG 3.57Å; V637-G786 PolarHBondContact N-O 2.89Å; V637-G786 VanDerWaalsContact N-O 3.13Å
638D53.3Low54.6Low90 Ų90105.7 Ų105.748%0.48156%0.562SS.*  trans-129.3135.3176-166.19.8000108.9R788 N793D638-R788 HydrophobicContact CB-CB 4.48Å; D638-R788 VanDerWaalsContact CG-CD 3.49Å; D638-R788 WeakPolarHBondContact OD2-CD 2.72Å; D638-R788 IonicContact OD2-NE 2.99Å; D638-N793 PolarHBondContact OD1-ND2 3.31Å
639Y54.7Low57.6Low77 Ų7799.3 Ų99.330%0.30253%0.532SS..  trans-123.4116.8-173-65.4-91.2000110.4V637 N793 R796 Q797V637-Y639 HydrophobicContact CB-CE2 3.97Å; V637-Y639 HydrophobicContact CG1-CD2 4.49Å; V637-Y639 HydrophobicContact CG1-CE1 4.48Å; V637-Y639 HydrophobicContact CG1-CE2 3.67Å; Y639-N793 PolarHBondContact N-OD1 3.37Å; Y639-R796 PolarHBondContact O-NH1 3.46Å; Y639-Q797 PolarHBondContact OH-NE2 3.05Å; Y639-Q797 VanDerWaalsContact OH-NE2 3.07Å
640S46.9Very low60.7Low123 Ų12393.9 Ų93.986%0.8650%0.496SS*.  trans-86.2-11-174.961.10000116.2
641L47.7Very low63.8Low131 Ų13191.5 Ų91.569%0.68648%0.479SS*.SBendtrans-91134.3-172.7-68.8170.1000112.2E643 R796L641-E643 PolarHBondContact O-N 2.91Å; L641-E643 VanDerWaalsContact O-N 3.07Å; L641-R796 PolarHBondContact O-NH1 3.36Å; L641-R796 PolarHBondContact O-NH2 2.64Å
642N50Low67Low158 Ų15885.3 Ų85.385%0.84544%0.443SS*.  trans-71.893171.5-88.6-21.8000111.8
643E60.2Low69.8Low112 Ų11286.2 Ų86.252%0.52345%0.447SS..  trans-84.6139.8165.1-75.1-174.2164.500111.9L641 L645 R796L641-E643 PolarHBondContact O-N 2.91Å; L641-E643 VanDerWaalsContact O-N 3.07Å; E643-L645 PolarHBondContact O-N 3.27Å; E643-L645 VanDerWaalsContact O-N 3.12Å; E643-R796 IonicContact OE2-NE 3.2Å
644N76Confident72.8Confident175 Ų17584.1 Ų84.194%0.93643%0.426SS*.  trans-74.495.1170.4-74.3-26.7000110.4
645L85.5Confident75.2Confident29 Ų2982.9 Ų82.915%0.15242%0.418CS..  trans-87151171.3-63.6-178.5000111.3E643 M792 M795 R796 N799 W840E643-L645 PolarHBondContact O-N 3.27Å; E643-L645 VanDerWaalsContact O-N 3.12Å; L645-M792 HydrophobicContact CD1-SD 3.58Å; L645-M792 VanDerWaalsContact CD1-SD 3.58Å; L645-M792 HydrophobicContact CG-SD 4.24Å; L645-M795 HydrophobicContact CB-CE 4.36Å; L645-M795 HydrophobicContact CD1-CB 3.45Å; L645-M795 VanDerWaalsContact CD1-CB 3.45Å; L645-M795 HydrophobicContact CD1-CE 4.49Å; L645-R796 HydrophobicContact CD1-CG 3.75Å; L645-R796 HydrophobicContact CD2-CG 4.45Å; L645-N799 HydrophobicContact CD2-CB 4.01Å; L645-N799 WeakPolarHBondContact CD2-ND2 3.28Å; L645-W840 HydrophobicContact CB-CZ2 4.41Å
646P90.6Very high77.6Confident58 Ų5883.5 Ų83.538%0.37743%0.428SS..  trans-64.9146.1176.828.4-35.2000111.3E648 L649 W840P646-E648 PolarHBondContact O-N 3.11Å; P646-L649 HydrophobicContact CG-CB 4.35Å; P646-L649 HydrophobicContact CG-CD1 4.39Å; P646-W840 HydrophobicContact CG-CZ2 3.97Å; P646-W840 WeakPolarHBondContact O-CZ2 3.09Å; P646-W840 PolarHBondContact O-NE1 3Å
647E90Very high79.6Confident143 Ų14385 Ų8567%0.66844%0.437SS*.SBendtrans-62.2-28.8176.9-71.5-164140.700112.7W840E647-W840 PolarHBondContact O-NE1 3.41Å
648E93.3Very high81.6Confident106 Ų10684.1 Ų84.150%0.49543%0.432SS..  trans-132.2138.9174.6-49-159.9133.200111.2P646 W840 K842P646-E648 PolarHBondContact O-N 3.11Å; E648-W840 WeakPolarHBondContact CA-O 3.39Å; E648-K842 PolarHBondContact OE1-N 3.25Å
649L94.8Very high83.7Confident14 Ų1480.8 Ų80.87%0.07342%0.417CS..EExtended strand (participates in β ladder)trans-140.6132.3172.5-177.2150.2000109.9P646 K654 I798 N799 G839 W840P646-L649 HydrophobicContact CG-CB 4.35Å; P646-L649 HydrophobicContact CG-CD1 4.39Å; L649-K654 HydrophobicContact CD1-CD 3.79Å; L649-K654 HydrophobicContact CG-CD 4.46Å; L649-I798 HydrophobicContact CD2-CG2 3.68Å; L649-N799 HydrophobicContact CD1-CB 4.21Å; L649-N799 VanDerWaalsContact CD1-OD1 3.26Å; L649-N799 WeakPolarHBondContact CD1-OD1 3.44Å; L649-G839 CarbonylContact O-C 3.5Å; L649-G839 WeakPolarHBondContact O-CA 3.4Å; L649-W840 HydrophobicContact CB-CD2 3.9Å; L649-W840 HydrophobicContact CB-CE3 3.85Å; L649-W840 HydrophobicContact CB-CH2 3.52Å; L649-W840 HydrophobicContact CB-CZ2 3.54Å; L649-W840 HydrophobicContact CB-CZ3 3.64Å; L649-W840 HydrophobicContact CD1-CH2 3.46Å; L649-W840 VanDerWaalsContact CD1-CH2 3.46Å; L649-W840 HydrophobicContact CD1-CZ2 4.14Å; L649-W840 HydrophobicContact CD1-CZ3 3.82Å; L649-W840 HydrophobicContact CD2-CE3 4.31Å; L649-W840 HydrophobicContact CD2-CH2 4.33Å; L649-W840 HydrophobicContact CD2-CZ3 3.85Å; L649-W840 HydrophobicContact CG-CH2 3.95Å; L649-W840 HydrophobicContact CG-CZ2 4.42Å; L649-W840 HydrophobicContact CG-CZ3 3.97Å; L649-W840 PolarHBondContact N-O 2.88Å; L649-W840 PolarHBondContact O-N 3.12Å
650D95.8Very high85.6Confident25 Ų2585.3 Ų85.313%0.13444%0.441CS..EExtended strand (participates in β ladder)trans-123115.7170-179.3-17.2000108.5R652 K653 K654D650-R652 PolarHBondContact O-N 3.4Å; D650-R652 VanDerWaalsContact O-N 3.07Å; D650-R652 VanDerWaalsContact OD1-CB 3.31Å; D650-R652 WeakPolarHBondContact OD1-CB 3.28Å; D650-R652 WeakPolarHBondContact OD1-CG 3.45Å; D650-R652 IonicContact OD1-CZ 3.76Å; D650-R652 PolarHBondContact OD1-N 3.25Å; D650-R652 IonicContact OD1-NE 2.67Å; D650-R652 PolarHBondContact OD1-NE 3.44Å; D650-R652 IonicContact OD1-NH2 2.65Å; D650-R652 IonicContact OD2-CZ 2.9Å; D650-R652 VanDerWaalsContact OD2-CZ 3.31Å; D650-R652 IonicContact OD2-NE 3.56Å; D650-R652 PolarHBondContact OD2-NE 3.04Å; D650-R652 VanDerWaalsContact OD2-NE 3.16Å; D650-R652 IonicContact OD2-NH2 2.79Å; D650-R652 PolarHBondContact OD2-NH2 3.33Å; D650-K653 HydrophobicContact CB-CB 4.35Å; D650-K653 HydrophobicContact CB-CD 4.06Å; D650-K653 HydrophobicContact CB-CG 4.04Å; D650-K653 PolarHBondContact O-N 3.11Å; D650-K654 PolarHBondContact O-N 2.79Å
651A96.2Very high87.9Confident0 Ų080 Ų800%040%0.403CS..Hα-helixtrans-56.7-28.1-177.300000112.9K653 K654 W655 I662 P803 I838A651-K653 VanDerWaalsContact C-N 3.33Å; A651-K653 PolarHBondContact O-N 3.06Å; A651-K654 PolarHBondContact O-N 3.26Å; A651-W655 HydrophobicContact CB-CE3 3.78Å; A651-W655 HydrophobicContact CB-CZ3 3.75Å; A651-W655 PolarHBondContact O-N 3.02Å; A651-I662 HydrophobicContact CB-CD1 4.17Å; A651-I662 HydrophobicContact CB-CG2 4.28Å; A651-P803 HydrophobicContact CB-CG 4.05Å; A651-I838 WeakPolarHBondContact CB-O 3.42Å; A651-I838 PolarHBondContact N-O 3.18Å
652R96.8Very high90.3Very high40 Ų4073.8 Ų73.815%0.15137%0.37CS..Hα-helixtrans-68.7-34.1177-58.1166.8-67-158.310.4112.1D650 A659 I662 S663 K864D650-R652 PolarHBondContact O-N 3.4Å; D650-R652 VanDerWaalsContact O-N 3.07Å; D650-R652 VanDerWaalsContact OD1-CB 3.31Å; D650-R652 WeakPolarHBondContact OD1-CB 3.28Å; D650-R652 WeakPolarHBondContact OD1-CG 3.45Å; D650-R652 IonicContact OD1-CZ 3.76Å; D650-R652 PolarHBondContact OD1-N 3.25Å; D650-R652 IonicContact OD1-NE 2.67Å; D650-R652 PolarHBondContact OD1-NE 3.44Å; D650-R652 IonicContact OD1-NH2 2.65Å; D650-R652 IonicContact OD2-CZ 2.9Å; D650-R652 VanDerWaalsContact OD2-CZ 3.31Å; D650-R652 IonicContact OD2-NE 3.56Å; D650-R652 PolarHBondContact OD2-NE 3.04Å; D650-R652 VanDerWaalsContact OD2-NE 3.16Å; D650-R652 IonicContact OD2-NH2 2.79Å; D650-R652 PolarHBondContact OD2-NH2 3.33Å; R652-A659 HydrophobicContact CB-CB 4.14Å; R652-A659 WeakPolarHBondContact O-CB 3.37Å; R652-I662 HydrophobicContact CG-CB 3.97Å; R652-I662 HydrophobicContact CG-CG2 3.57Å; R652-S663 WeakPolarHBondContact CD-OG 3.46Å; R652-K864 VanDerWaalsContact NH1-CE 3.32Å
653K97Very high92.4Very high165 Ų16568.7 Ų68.772%0.71735%0.347SS*.Hα-helixtrans-77.8-39.6177-62.2-178.1-174.5174.70110.9D650 A651D650-K653 HydrophobicContact CB-CB 4.35Å; D650-K653 HydrophobicContact CB-CD 4.06Å; D650-K653 HydrophobicContact CB-CG 4.04Å; D650-K653 PolarHBondContact O-N 3.11Å; A651-K653 VanDerWaalsContact C-N 3.33Å; A651-K653 PolarHBondContact O-N 3.06Å
654K96.9Very high94.1Very high89 Ų8966 Ų6639%0.38734%0.335SS..Hα-helixtrans-71.3-36.1-178.5-173.2165.3-176.4179.70113.2L649 D650 A651 P656 N799L649-K654 HydrophobicContact CD1-CD 3.79Å; L649-K654 HydrophobicContact CG-CD 4.46Å; D650-K654 PolarHBondContact O-N 2.79Å; A651-K654 PolarHBondContact O-N 3.26Å; K654-P656 WeakPolarHBondContact O-CD 3.38Å; K654-N799 PolarHBondContact NZ-O 2.92Å; K654-N799 PolarHBondContact NZ-OD1 3.23Å
655W97.3Very high95Very high40 Ų4058.5 Ų58.515%0.15230%0.295CS..  trans-120.377178.3-62.5-79.7000111.1A651 N657 C658 A659 I689 I798 N799A651-W655 HydrophobicContact CB-CE3 3.78Å; A651-W655 HydrophobicContact CB-CZ3 3.75Å; A651-W655 PolarHBondContact O-N 3.02Å; W655-N657 VanDerWaalsContact C-N 3.28Å; W655-N657 PolarHBondContact O-N 3.12Å; W655-C658 HydrophobicContact CB-CB 4.24Å; W655-C658 CarbonylContact O-C 3.52Å; W655-C658 PolarHBondContact O-N 3.32Å; W655-A659 PolarHBondContact O-N 2.81Å; W655-A659 VanDerWaalsContact O-N 3.09Å; W655-I689 HydrophobicContact CB-CG1 4.11Å; W655-I689 HydrophobicContact CD2-CD1 3.81Å; W655-I689 HydrophobicContact CD2-CG1 3.93Å; W655-I689 HydrophobicContact CD2-CG2 4.22Å; W655-I689 HydrophobicContact CE3-CD1 3.8Å; W655-I689 HydrophobicContact CE3-CG1 4.38Å; W655-I689 HydrophobicContact CG-CD1 4.2Å; W655-I689 HydrophobicContact CG-CG1 3.78Å; W655-I689 HydrophobicContact CG-CG2 4.24Å; W655-I689 HydrophobicContact CZ2-CG2 4.32Å; W655-I689 HydrophobicContact CZ3-CD1 4.27Å; W655-I798 VanDerWaalsContact CH2-O 3.25Å; W655-I798 WeakPolarHBondContact CH2-O 3.15Å; W655-N799 WeakPolarHBondContact CH2-O 3.31Å; W655-N799 WeakPolarHBondContact CZ2-O 3.36Å
656P96.9Very high95.4Very high90 Ų9057.7 Ų57.758%0.58429%0.29SS*.G310 helixtrans-59.6-35.4-174.422-33.2000113.4K654 C658 A659K654-P656 WeakPolarHBondContact O-CD 3.38Å; P656-C658 PolarHBondContact O-N 3.14Å; P656-C658 VanDerWaalsContact O-N 3.16Å; P656-A659 VanDerWaalsContact O-CB 3.25Å; P656-A659 WeakPolarHBondContact O-CB 3.27Å; P656-A659 PolarHBondContact O-N 2.94Å; P656-A659 VanDerWaalsContact O-N 3.09Å
657N96.7Very high95.6Very high99 Ų9956.2 Ų56.253%0.52928%0.279SS..G310 helixtrans-63.9-19.1176.3-64.4-23.3000113.3W655 N692W655-N657 VanDerWaalsContact C-N 3.28Å; W655-N657 PolarHBondContact O-N 3.12Å; N657-N692 PolarHBondContact ND2-OD1 3.42Å; N657-N692 VanDerWaalsContact ND2-OD1 3.11Å
658C97.8Very high95.8Very high2 Ų249.4 Ų49.41%0.01425%0.248CC..G310 helixtrans-109.9-0.5177.3-62.40000112.7W655 P656 Q660 L661 I662 C688 I689W655-C658 HydrophobicContact CB-CB 4.24Å; W655-C658 CarbonylContact O-C 3.52Å; W655-C658 PolarHBondContact O-N 3.32Å; P656-C658 PolarHBondContact O-N 3.14Å; P656-C658 VanDerWaalsContact O-N 3.16Å; C658-Q660 VanDerWaalsContact C-N 3.29Å; C658-Q660 PolarHBondContact O-N 2.63Å; C658-L661 PolarHBondContact O-N 3.13Å; C658-L661 VanDerWaalsContact O-N 3.1Å; C658-I662 HydrophobicContact CB-CD1 3.79Å; C658-I662 HydrophobicContact CB-CG1 4.31Å; C658-I662 WeakPolarHBondContact O-CG1 3.41Å; C658-I662 PolarHBondContact O-N 2.84Å; C658-C688 WeakPolarHBondContact CA-SG 3.31Å; C658-C688 HydrophobicContact CB-CB 3.95Å; C658-C688 WeakPolarHBondContact CB-SG 3.26Å; C658-C688 WeakPolarHBondContact SG-CB 3.13Å; C658-C688 PolarHBondContact SG-O 3.07Å; C658-C688 VanDerWaalsContact SG-O 3.33Å; C658-C688 CovalentContact SG-SG 2.04Å; C658-C688 PolarHBondContact SG-SG 3.35Å; C658-I689 HydrophobicContact CB-CG1 4.41Å; C658-I689 PolarHBondContact SG-N 3.39Å; C658-I689 VanDerWaalsContact SG-N 3.43Å
659A96.5Very high95.8Very high21 Ų2144.4 Ų44.417%0.17422%0.224CC..Hα-helixtrans-59.5-39.1-173.300000112.5R652 W655 P656 S663R652-A659 HydrophobicContact CB-CB 4.14Å; R652-A659 WeakPolarHBondContact O-CB 3.37Å; W655-A659 PolarHBondContact O-N 2.81Å; W655-A659 VanDerWaalsContact O-N 3.09Å; P656-A659 VanDerWaalsContact O-CB 3.25Å; P656-A659 WeakPolarHBondContact O-CB 3.27Å; P656-A659 PolarHBondContact O-N 2.94Å; P656-A659 VanDerWaalsContact O-N 3.09Å; A659-S663 WeakPolarHBondContact O-CB 3.3Å; A659-S663 PolarHBondContact O-N 2.83Å; A659-S663 PolarHBondContact O-OG 3.28Å
660Q94.8Very high95.6Very high172 Ų17243.9 Ų43.980%0.80422%0.222SC*.Hα-helixtrans-62.1-43.2177.4-68.4-174.8-1000111.7C658 I664C658-Q660 VanDerWaalsContact C-N 3.29Å; C658-Q660 PolarHBondContact O-N 2.63Å; Q660-I664 WeakPolarHBondContact O-CG1 3.29Å
661L95.9Very high95.5Very high10 Ų1042.7 Ų42.75%0.05222%0.215CC..Hα-helixtrans-68.8-48.6178.7-174.169.5000111.6C658 S663 I664 C688 F698C658-L661 PolarHBondContact O-N 3.13Å; C658-L661 VanDerWaalsContact O-N 3.1Å; L661-S663 PolarHBondContact O-N 2.78Å; L661-I664 PolarHBondContact O-N 3.45Å; L661-C688 HydrophobicContact CD2-CB 3.8Å; L661-F698 HydrophobicContact CD1-CD1 3.81Å; L661-F698 HydrophobicContact CD1-CD2 4.44Å; L661-F698 HydrophobicContact CD1-CE1 3.57Å; L661-F698 HydrophobicContact CD1-CE2 4.23Å; L661-F698 HydrophobicContact CD1-CG 4.25Å; L661-F698 HydrophobicContact CD1-CZ 3.8Å
662I96.6Very high95.5Very high1 Ų142.7 Ų42.71%0.00522%0.216CC..Hα-helixtrans-63.5-31.4-179.5-62.9166000110.9A651 R652 C658 I664 D685 I689 P803 R836 I838A651-I662 HydrophobicContact CB-CD1 4.17Å; A651-I662 HydrophobicContact CB-CG2 4.28Å; R652-I662 HydrophobicContact CG-CB 3.97Å; R652-I662 HydrophobicContact CG-CG2 3.57Å; C658-I662 HydrophobicContact CB-CD1 3.79Å; C658-I662 HydrophobicContact CB-CG1 4.31Å; C658-I662 WeakPolarHBondContact O-CG1 3.41Å; C658-I662 PolarHBondContact O-N 2.84Å; I662-I664 VanDerWaalsContact C-N 3.28Å; I662-I664 PolarHBondContact O-N 3.4Å; I662-D685 HydrophobicContact CG1-CB 4.16Å; I662-I689 HydrophobicContact CD1-CD1 4.32Å; I662-P803 HydrophobicContact CG2-CG 4.49Å; I662-R836 PolarHBondContact O-NH2 2.65Å; I662-I838 HydrophobicContact CG2-CB 4.29Å; I662-I838 HydrophobicContact CG2-CG2 4.05Å
663S95.2Very high95.4Very high51 Ų5140.8 Ų40.836%0.35721%0.209SC..THydrogen-bonded Turntrans-71.7-16.9179.9-64.80000114.5R652 A659 L661 I665R652-S663 WeakPolarHBondContact CD-OG 3.46Å; A659-S663 WeakPolarHBondContact O-CB 3.3Å; A659-S663 PolarHBondContact O-N 2.83Å; A659-S663 PolarHBondContact O-OG 3.28Å; L661-S663 PolarHBondContact O-N 2.78Å; S663-I665 PolarHBondContact O-N 2.9Å
664I95.2Very high95.4Very high55 Ų5533 Ų3328%0.28217%0.174SC..PPolyproline II helixtrans-75.4124.5-177.4-67.2163.8000110Q660 L661 I662 F698 L737 R836Q660-I664 WeakPolarHBondContact O-CG1 3.29Å; L661-I664 PolarHBondContact O-N 3.45Å; I662-I664 VanDerWaalsContact C-N 3.28Å; I662-I664 PolarHBondContact O-N 3.4Å; I664-F698 HydrophobicContact CB-CZ 4.04Å; I664-F698 HydrophobicContact CD1-CE2 3.98Å; I664-F698 HydrophobicContact CD1-CZ 3.5Å; I664-F698 HydrophobicContact CG1-CZ 4.35Å; I664-F698 HydrophobicContact CG2-CE1 4.48Å; I664-F698 HydrophobicContact CG2-CZ 3.81Å; I664-L737 HydrophobicContact CG2-CD1 4.17Å; I664-L737 HydrophobicContact CG2-CD2 4.18Å; I664-R836 PolarHBondContact O-NH2 3.37Å
665I94.5Very high95.3Very high19 Ų1928.7 Ų28.710%0.09716%0.156CC..PPolyproline II helixtrans-93.3122.9170.2-56.4-53.9000108.2S663 A852 N853 N857 K864S663-I665 PolarHBondContact O-N 2.9Å; I665-A852 HydrophobicContact CD1-CB 3.74Å; I665-N853 WeakPolarHBondContact CG2-O 3.42Å; I665-N857 WeakPolarHBondContact CB-OD1 3.27Å; I665-K864 HydrophobicContact CD1-CG 3.93Å
666K94.6Very high95.3Very high11 Ų1126.8 Ų26.85%0.04815%0.149CC..PPolyproline II helixtrans-83.6157.9176.1-67.9-170176.3-179.80111.1V677 D701 L737 S854 G856K666-V677 HydrophobicContact CB-CG1 3.75Å; K666-V677 HydrophobicContact CD-CG1 3.87Å; K666-V677 HydrophobicContact CG-CG1 4.42Å; K666-D701 IonicContact NZ-OD1 3.8Å; K666-D701 PolarHBondContact NZ-OD1 2.9Å; K666-L737 HydrophobicContact CG-CD2 3.97Å; K666-S854 CarbonylContact O-C 3.58Å; K666-S854 VanDerWaalsContact O-CA 3.25Å; K666-S854 WeakPolarHBondContact O-CA 3.1Å; K666-G856 PolarHBondContact O-N 2.99Å; K666-G856 VanDerWaalsContact O-N 3.17Å
667D94.1Very high95.3Very high27 Ų2722.7 Ų22.714%0.14412%0.122CC..BIsolated β-bridgetrans-118.7114171.8-173.2-10.3000108.6S669 Y747 P751 G752D667-S669 PolarHBondContact O-N 2.83Å; D667-S669 WeakPolarHBondContact OD1-CA 3.46Å; D667-S669 PolarHBondContact OD1-N 2.97Å; D667-Y747 WeakPolarHBondContact O-CE1 3.38Å; D667-P751 HydrophobicContact CB-CB 3.99Å; D667-P751 VanDerWaalsContact OD2-CA 3.25Å; D667-P751 WeakPolarHBondContact OD2-CA 3.25Å; D667-P751 VanDerWaalsContact OD2-CB 3.27Å; D667-P751 WeakPolarHBondContact OD2-CB 3.44Å; D667-G752 PolarHBondContact OD2-N 2.91Å
668Q94.9Very high95.2Very high0 Ų018.2 Ų18.20%010%0.099CC..  trans-71.8-2.2176.774.8-173.982.200112.9L619 C671 V677 Y747 H833 S854L619-Q668 HydrophobicContact CD2-CG 4.37Å; L619-Q668 PolarHBondContact O-NE2 2.85Å; Q668-C671 PolarHBondContact NE2-O 3.05Å; Q668-C671 PolarHBondContact O-N 2.81Å; Q668-V677 HydrophobicContact CB-CG2 4.15Å; Q668-Y747 PolarHBondContact O-OH 3.42Å; Q668-H833 PolarHBondContact OE1-CE1 2.99Å; Q668-S854 WeakPolarHBondContact CG-O 3.49Å; Q668-S854 PolarHBondContact N-O 3.12Å; Q668-S854 PolarHBondContact OE1-O 3.13Å; Q668-S854 PolarHBondContact OE1-OG 2.98Å
669S93.3Very high95.1Very high1 Ų118.1 Ų18.11%0.00710%0.098CC..THydrogen-bonded Turntrans56.9-143.7-177.4-1650000110.9R607 L619 D667 C671 P750R607-S669 PolarHBondContact NH2-O 3Å; L619-S669 WeakPolarHBondContact CD2-O 3.39Å; D667-S669 PolarHBondContact O-N 2.83Å; D667-S669 WeakPolarHBondContact OD1-CA 3.46Å; D667-S669 PolarHBondContact OD1-N 2.97Å; S669-C671 VanDerWaalsContact C-N 3.34Å; S669-C671 PolarHBondContact O-N 2.85Å; S669-P750 WeakPolarHBondContact CB-O 3.28Å; S669-P750 PolarHBondContact OG-O 3.2Å
670N90.9Very high95.1Very high3 Ų317.1 Ų17.12%0.0169%0.09CC..THydrogen-bonded Turntrans-95.842.9175.3-162.917000113.3N753 R754 K756 A757N670-N753 WeakPolarHBondContact CB-O 3.42Å; N670-R754 PolarHBondContact ND2-O 3.48Å; N670-K756 PolarHBondContact ND2-N 3.05Å; N670-A757 VanDerWaalsContact O-CB 3.23Å; N670-A757 WeakPolarHBondContact O-CB 3.41Å; N670-A757 PolarHBondContact O-N 2.83Å; N670-A757 VanDerWaalsContact O-N 3.11Å
671C94.2Very high95.2Very high0 Ų09.2 Ų9.20%05%0.053CC..SBendtrans-119.6138177.2-179.10000109.8Q668 S669 S673 C715 F749 A757Q668-C671 PolarHBondContact NE2-O 3.05Å; Q668-C671 PolarHBondContact O-N 2.81Å; S669-C671 VanDerWaalsContact C-N 3.34Å; S669-C671 PolarHBondContact O-N 2.85Å; C671-S673 PolarHBondContact O-N 3.49Å; C671-S673 VanDerWaalsContact SG-CB 3.52Å; C671-C715 HydrophobicContact CB-CB 4.04Å; C671-C715 WeakPolarHBondContact CB-SG 3.3Å; C671-C715 WeakPolarHBondContact SG-CA 3.5Å; C671-C715 WeakPolarHBondContact SG-CB 3.23Å; C671-C715 CovalentContact SG-SG 2.04Å; C671-C715 PolarHBondContact SG-SG 3.14Å; C671-F749 HydrophobicContact CB-CD2 4.05Å; C671-F749 HydrophobicContact CB-CE2 3.93Å; C671-A757 HydrophobicContact CB-CB 3.56Å
672G94.2Very high95.2Very high1 Ų18.7 Ų8.71%0.015%0.051CC..SBendtrans-75.850.3173.200000112.7R618 G621 W675 C715R618-G672 WeakPolarHBondContact O-CA 3.47Å; R618-G672 PolarHBondContact O-N 3.41Å; G621-G672 WeakPolarHBondContact CA-O 3.35Å; G672-W675 VanDerWaalsContact O-CD1 3.3Å; G672-W675 PolarHBondContact O-NE1 2.9Å; G672-C715 VanDerWaalsContact CA-O 3.29Å; G672-C715 WeakPolarHBondContact CA-O 3.4Å; G672-C715 PolarHBondContact N-O 3.15Å
673S96.3Very high95.1Very high0 Ų08.7 Ų8.70%05%0.05CC..  trans-102.212.6-172.754.60000113.8C671 W675 A676 V677 Y747C671-S673 PolarHBondContact O-N 3.49Å; C671-S673 VanDerWaalsContact SG-CB 3.52Å; S673-W675 PolarHBondContact O-N 3.3Å; S673-W675 VanDerWaalsContact O-N 3.1Å; S673-A676 WeakPolarHBondContact O-CA 3.32Å; S673-A676 PolarHBondContact O-N 3.32Å; S673-V677 WeakPolarHBondContact O-CG2 3.37Å; S673-V677 PolarHBondContact O-N 3.2Å; S673-Y747 PolarHBondContact OG-OH 3.33Å
674C95.9Very high95.2Very high0 Ų06.3 Ų6.30%03%0.034CC..Hα-helixtrans-54.5-33.8-178.563.10000113.1G621 A676 S678 H833G621-C674 PolarHBondContact N-SG 2.95Å; C674-A676 VanDerWaalsContact C-N 3.35Å; C674-A676 PolarHBondContact O-N 2.78Å; C674-S678 VanDerWaalsContact O-CB 3.23Å; C674-S678 WeakPolarHBondContact O-CB 3.48Å; C674-S678 PolarHBondContact O-N 3.05Å; C674-S678 PolarHBondContact O-OG 3.27Å; C674-H833 WeakPolarHBondContact CB-CE1 3.44Å; C674-H833 VanDerWaalsContact CB-ND1 3.34Å; C674-H833 WeakPolarHBondContact CB-ND1 3.46Å; C674-H833 PolarHBondContact SG-ND1 2.77Å
675W94.7Very high95.2Very high0 Ų03.7 Ų3.70%02%0.02CC..Hα-helixtrans-61.5-38.1173.764.7-89.6000113.2G672 S673 A679 L704 L705 C711 G714 P720 A723G672-W675 VanDerWaalsContact O-CD1 3.3Å; G672-W675 PolarHBondContact O-NE1 2.9Å; S673-W675 PolarHBondContact O-N 3.3Å; S673-W675 VanDerWaalsContact O-N 3.1Å; W675-A679 WeakPolarHBondContact O-CB 3.32Å; W675-A679 PolarHBondContact O-N 2.64Å; W675-L704 HydrophobicContact CZ3-CB 4.44Å; W675-L705 HydrophobicContact CZ2-CD1 4.16Å; W675-C711 HydrophobicContact CE3-CB 4.17Å; W675-C711 HydrophobicContact CH2-CB 3.57Å; W675-C711 HydrophobicContact CZ3-CB 3.3Å; W675-G714 PolarHBondContact NE1-O 2.8Å; W675-P720 HydrophobicContact CB-CG 3.9Å; W675-A723 HydrophobicContact CE3-CB 4.14Å; W675-A723 HydrophobicContact CZ3-CB 4.14Å
676A97.2Very high95.3Very high0 Ų03 Ų30%02%0.017CC..Hα-helixtrans-80.7-42.2177.700000111.6S673 C674 A679 A680 L704 L705S673-A676 WeakPolarHBondContact O-CA 3.32Å; S673-A676 PolarHBondContact O-N 3.32Å; C674-A676 VanDerWaalsContact C-N 3.35Å; C674-A676 PolarHBondContact O-N 2.78Å; A676-A679 PolarHBondContact O-N 2.87Å; A676-A680 VanDerWaalsContact O-CB 3.3Å; A676-A680 WeakPolarHBondContact O-CB 3.42Å; A676-A680 PolarHBondContact O-N 2.89Å; A676-L704 HydrophobicContact CB-CB 3.93Å; A676-L705 HydrophobicContact CB-CB 4.48Å
677V97.4Very high95.2Very high4 Ų42.7 Ų2.72%0.0242%0.015CC..Hα-helixtrans-67.1-46.1-177.91760000111.4K666 Q668 S673 S681 D701 Y747K666-V677 HydrophobicContact CB-CG1 3.75Å; K666-V677 HydrophobicContact CD-CG1 3.87Å; K666-V677 HydrophobicContact CG-CG1 4.42Å; Q668-V677 HydrophobicContact CB-CG2 4.15Å; S673-V677 WeakPolarHBondContact O-CG2 3.37Å; S673-V677 PolarHBondContact O-N 3.2Å; V677-S681 VanDerWaalsContact O-CB 3.27Å; V677-S681 WeakPolarHBondContact O-CB 3.23Å; V677-S681 PolarHBondContact O-N 3.13Å; V677-S681 PolarHBondContact O-OG 2.91Å; V677-D701 HydrophobicContact CG2-CB 4.23Å; V677-Y747 HydrophobicContact CG2-CE2 4.46Å
678S95.2Very high95.3Very high5 Ų51.4 Ų1.44%0.0351%0.008CC..Hα-helixtrans-64.5-44.1176.559.50000111.1C674 S681 V682 A834C674-S678 VanDerWaalsContact O-CB 3.23Å; C674-S678 WeakPolarHBondContact O-CB 3.48Å; C674-S678 PolarHBondContact O-N 3.05Å; C674-S678 PolarHBondContact O-OG 3.27Å; S678-S681 PolarHBondContact O-N 2.04Å; S678-V682 PolarHBondContact O-N 3.42Å; S678-A834 VanDerWaalsContact OG-CB 3.3Å; S678-A834 WeakPolarHBondContact OG-CB 3.48Å
679A95.3Very high95.4Very high0 Ų02.3 Ų2.30%01%0.013CC..Hα-helixtrans-60.2-57.4177.400000111.9W675 A676 S681 V682 M683 L704 A723 I805W675-A679 WeakPolarHBondContact O-CB 3.32Å; W675-A679 PolarHBondContact O-N 2.64Å; A676-A679 PolarHBondContact O-N 2.87Å; A679-S681 PolarHBondContact O-N 2.63Å; A679-V682 PolarHBondContact O-N 3.11Å; A679-V682 VanDerWaalsContact O-N 3.12Å; A679-M683 HydrophobicContact CB-CE 4.02Å; A679-M683 WeakPolarHBondContact O-CG 3.05Å; A679-M683 PolarHBondContact O-N 3.09Å; A679-L704 HydrophobicContact CB-CD1 4.23Å; A679-A723 HydrophobicContact CB-CB 3.9Å; A679-I805 HydrophobicContact CB-CD1 3.82Å
680A97Very high95.4Very high0 Ų06.2 Ų6.20%03%0.033CC..Hα-helixtrans-57.8-34.4178.800000113A676 M683 S684 D701 L704A676-A680 VanDerWaalsContact O-CB 3.3Å; A676-A680 WeakPolarHBondContact O-CB 3.42Å; A676-A680 PolarHBondContact O-N 2.89Å; A680-M683 PolarHBondContact O-N 3.13Å; A680-S684 WeakPolarHBondContact O-CB 3.05Å; A680-S684 PolarHBondContact O-N 2.87Å; A680-S684 PolarHBondContact O-OG 2.95Å; A680-D701 HydrophobicContact CB-CB 3.79Å; A680-L704 HydrophobicContact CB-CD1 4.09Å
681S96.5Very high95.5Very high5 Ų57.1 Ų7.14%0.0354%0.039CC..Hα-helixtrans-66.5-45.6177.2-58.90000111.7V677 S678 A679 S684 D685V677-S681 VanDerWaalsContact O-CB 3.27Å; V677-S681 WeakPolarHBondContact O-CB 3.23Å; V677-S681 PolarHBondContact O-N 3.13Å; V677-S681 PolarHBondContact O-OG 2.91Å; S678-S681 PolarHBondContact O-N 2.04Å; A679-S681 PolarHBondContact O-N 2.63Å; S681-S684 WeakPolarHBondContact O-CB 3.43Å; S681-S684 PolarHBondContact O-N 3.19Å; S681-D685 PolarHBondContact O-N 3.01Å
682V95.8Very high95.5Very high0 Ų012.4 Ų12.40%07%0.068CC..Hα-helixtrans-64.4-41.11751680000111.6S678 A679 S684 D685 R686 P803 I805 R836 L876S678-V682 PolarHBondContact O-N 3.42Å; A679-V682 PolarHBondContact O-N 3.11Å; A679-V682 VanDerWaalsContact O-N 3.12Å; V682-S684 VanDerWaalsContact C-N 3.29Å; V682-S684 PolarHBondContact O-N 2.03Å; V682-D685 PolarHBondContact O-N 3.5Å; V682-R686 HydrophobicContact CG1-CG 4.34Å; V682-R686 WeakPolarHBondContact O-CB 3.27Å; V682-R686 WeakPolarHBondContact O-CG 3.29Å; V682-R686 PolarHBondContact O-N 3.39Å; V682-P803 WeakPolarHBondContact CG1-O 3.28Å; V682-P803 HydrophobicContact CG2-CB 4.48Å; V682-I805 HydrophobicContact CB-CD1 4.39Å; V682-I805 HydrophobicContact CB-CG1 3.75Å; V682-I805 HydrophobicContact CG1-CG1 4.07Å; V682-I805 HydrophobicContact CG2-CG1 3.56Å; V682-R836 HydrophobicContact CG2-CB 4.21Å; V682-R836 HydrophobicContact CG2-CG 3.68Å; V682-L876 HydrophobicContact CG1-CD1 4.2Å
683M95.1Very high95.4Very high0 Ų013.4 Ų13.40%08%0.077CC..Hα-helixtrans-59.3-42.2175.1-59.3169.4-17800111.4A679 A680 T687 L699 L704 A723 L724 W727 I732 L876A679-M683 HydrophobicContact CB-CE 4.02Å; A679-M683 WeakPolarHBondContact O-CG 3.05Å; A679-M683 PolarHBondContact O-N 3.09Å; A680-M683 PolarHBondContact O-N 3.13Å; M683-T687 VanDerWaalsContact O-CB 3.3Å; M683-T687 WeakPolarHBondContact O-CB 3.45Å; M683-T687 PolarHBondContact O-N 2.93Å; M683-T687 PolarHBondContact O-OG1 3.29Å; M683-L699 HydrophobicContact CB-CD1 3.53Å; M683-L704 HydrophobicContact CE-CD1 4.1Å; M683-L704 HydrophobicContact SD-CD1 4.3Å; M683-A723 WeakPolarHBondContact CE-O 3.2Å; M683-L724 HydrophobicContact CE-CD2 3.62Å; M683-W727 HydrophobicContact CB-CD2 4.14Å; M683-W727 HydrophobicContact CB-CE3 4.07Å; M683-W727 HydrophobicContact CB-CH2 3.85Å; M683-W727 HydrophobicContact CB-CZ2 3.93Å; M683-W727 HydrophobicContact CB-CZ3 3.95Å; M683-W727 HydrophobicContact CE-CB 3.58Å; M683-W727 HydrophobicContact CE-CD2 4.18Å; M683-W727 HydrophobicContact CE-CE3 4.16Å; M683-W727 HydrophobicContact CE-CG 4Å; M683-W727 HydrophobicContact CG-CD2 3.64Å; M683-W727 HydrophobicContact CG-CE3 3.4Å; M683-W727 VanDerWaalsContact CG-CE3 3.4Å; M683-W727 HydrophobicContact CG-CG 4.3Å; M683-W727 HydrophobicContact CG-CH2 4.1Å; M683-W727 HydrophobicContact CG-CZ2 4.33Å; M683-W727 HydrophobicContact CG-CZ3 3.69Å; M683-W727 HydrophobicContact SD-CB 3.94Å; M683-W727 HydrophobicContact SD-CD2 3.75Å; M683-W727 HydrophobicContact SD-CE3 4.03Å; M683-W727 HydrophobicContact SD-CG 3.74Å; M683-I732 HydrophobicContact SD-CG1 4.04Å; M683-L876 HydrophobicContact CG-CD1 4.31Å
684S96.2Very high95.1Very high1 Ų122.5 Ų22.51%0.00712%0.117CC..Hα-helixtrans-64.7-48.5178.6-53.20000111.3A680 S681 V682 T687 C688 L699A680-S684 WeakPolarHBondContact O-CB 3.05Å; A680-S684 PolarHBondContact O-N 2.87Å; A680-S684 PolarHBondContact O-OG 2.95Å; S681-S684 WeakPolarHBondContact O-CB 3.43Å; S681-S684 PolarHBondContact O-N 3.19Å; V682-S684 VanDerWaalsContact C-N 3.29Å; V682-S684 PolarHBondContact O-N 2.03Å; S684-T687 PolarHBondContact O-N 3.45Å; S684-C688 PolarHBondContact O-N 2.96Å; S684-L699 PolarHBondContact OG-N 3.48Å
685D96.8Very high94.8Very high0 Ų024 Ų240%013%0.127CC..Hα-helixtrans-62.8-48.1-178.3-65.4-17.1000111.4I662 S681 V682 T687 C688 I689 P803 R836I662-D685 HydrophobicContact CG1-CB 4.16Å; S681-D685 PolarHBondContact O-N 3.01Å; V682-D685 PolarHBondContact O-N 3.5Å; D685-T687 VanDerWaalsContact C-N 3.31Å; D685-T687 PolarHBondContact O-N 2.95Å; D685-C688 WeakPolarHBondContact O-CB 3.01Å; D685-C688 PolarHBondContact O-N 3.48Å; D685-I689 WeakPolarHBondContact O-CB 3.43Å; D685-I689 VanDerWaalsContact O-CG1 3.3Å; D685-I689 WeakPolarHBondContact O-CG1 3.37Å; D685-I689 PolarHBondContact O-N 2.99Å; D685-P803 HydrophobicContact CB-CB 4.36Å; D685-P803 HydrophobicContact CB-CG 3.97Å; D685-R836 IonicContact OD1-NH1 3.92Å; D685-R836 PolarHBondContact OD1-NH1 2.88Å; D685-R836 WeakPolarHBondContact OD2-CD 3.45Å; D685-R836 IonicContact OD2-CZ 3.34Å; D685-R836 IonicContact OD2-NE 2.81Å; D685-R836 IonicContact OD2-NH1 3.03Å; D685-R836 PolarHBondContact OD2-NH1 2.74Å
686R94.8Very high94.6Very high6 Ų626.5 Ų26.52%0.02315%0.147CC..Hα-helixtrans-66.3-33.8179.9-67.2-165170-150.4-14.6112.3V682 I689 L690 Q797 Y801 G802 P803 V804 L876 V878V682-R686 HydrophobicContact CG1-CG 4.34Å; V682-R686 WeakPolarHBondContact O-CB 3.27Å; V682-R686 WeakPolarHBondContact O-CG 3.29Å; V682-R686 PolarHBondContact O-N 3.39Å; R686-I689 PolarHBondContact O-N 3.26Å; R686-L690 VanDerWaalsContact O-CB 3.31Å; R686-L690 WeakPolarHBondContact O-CB 3.34Å; R686-L690 PolarHBondContact O-N 3.1Å; R686-Q797 PolarHBondContact NH2-O 3.49Å; R686-Y801 WeakPolarHBondContact CG-O 3.26Å; R686-G802 PolarHBondContact NH2-O 3.36Å; R686-P803 PolarHBondContact NE-O 2.99Å; R686-P803 PolarHBondContact NH2-O 2.94Å; R686-V804 VanDerWaalsContact NH2-CG1 3.29Å; R686-L876 VanDerWaalsContact NH1-N 3.19Å; R686-L876 PolarHBondContact NH1-O 2.94Å; R686-V878 HydrophobicContact CB-CG2 3.89Å
687T94.2Very high94.4Very high3 Ų331.1 Ų31.12%0.01817%0.167CC..Hα-helixtrans-63.6-43.3172.3-600000111.3M683 S684 D685 T691 T695 V880M683-T687 VanDerWaalsContact O-CB 3.3Å; M683-T687 WeakPolarHBondContact O-CB 3.45Å; M683-T687 PolarHBondContact O-N 2.93Å; M683-T687 PolarHBondContact O-OG1 3.29Å; S684-T687 PolarHBondContact O-N 3.45Å; D685-T687 VanDerWaalsContact C-N 3.31Å; D685-T687 PolarHBondContact O-N 2.95Å; T687-T691 WeakPolarHBondContact O-CB 3.41Å; T687-T691 VanDerWaalsContact O-CG2 3.28Å; T687-T691 WeakPolarHBondContact O-CG2 3.19Å; T687-T691 PolarHBondContact O-N 3.28Å; T687-T691 VanDerWaalsContact O-N 3.15Å; T687-T691 PolarHBondContact O-OG1 3.31Å; T687-T695 HydrophobicContact CG2-CG2 3.82Å; T687-V880 HydrophobicContact CG2-CG2 4.03Å
688C96.4Very high94.3Very high0 Ų032.1 Ų32.10%017%0.171CC..Hα-helixtrans-63.5-48.2175.3-177.10000111.6C658 L661 S684 D685 L690 T691 N692 G693 T695C658-C688 WeakPolarHBondContact CA-SG 3.31Å; C658-C688 HydrophobicContact CB-CB 3.95Å; C658-C688 WeakPolarHBondContact CB-SG 3.26Å; C658-C688 WeakPolarHBondContact SG-CB 3.13Å; C658-C688 PolarHBondContact SG-O 3.07Å; C658-C688 VanDerWaalsContact SG-O 3.33Å; C658-C688 CovalentContact SG-SG 2.04Å; C658-C688 PolarHBondContact SG-SG 3.35Å; L661-C688 HydrophobicContact CD2-CB 3.8Å; S684-C688 PolarHBondContact O-N 2.96Å; D685-C688 WeakPolarHBondContact O-CB 3.01Å; D685-C688 PolarHBondContact O-N 3.48Å; C688-L690 PolarHBondContact O-N 3.37Å; C688-T691 CarbonylContact O-C 3.43Å; C688-T691 PolarHBondContact O-N 3.46Å; C688-T691 PolarHBondContact O-OG1 2.97Å; C688-N692 PolarHBondContact O-N 2.01Å; C688-G693 PolarHBondContact O-N 2.97Å; C688-T695 WeakPolarHBondContact CA-O 3.12Å
689I96.1Very high94.4Very high20 Ų2032.1 Ų32.110%0.10317%0.171CC..Hα-helixtrans-59.5-49.8-177.8-73.3169.8000110.7W655 C658 I662 D685 R686 T691 N692W655-I689 HydrophobicContact CB-CG1 4.11Å; W655-I689 HydrophobicContact CD2-CD1 3.81Å; W655-I689 HydrophobicContact CD2-CG1 3.93Å; W655-I689 HydrophobicContact CD2-CG2 4.22Å; W655-I689 HydrophobicContact CE3-CD1 3.8Å; W655-I689 HydrophobicContact CE3-CG1 4.38Å; W655-I689 HydrophobicContact CG-CD1 4.2Å; W655-I689 HydrophobicContact CG-CG1 3.78Å; W655-I689 HydrophobicContact CG-CG2 4.24Å; W655-I689 HydrophobicContact CZ2-CG2 4.32Å; W655-I689 HydrophobicContact CZ3-CD1 4.27Å; C658-I689 HydrophobicContact CB-CG1 4.41Å; C658-I689 PolarHBondContact SG-N 3.39Å; C658-I689 VanDerWaalsContact SG-N 3.43Å; I662-I689 HydrophobicContact CD1-CD1 4.32Å; D685-I689 WeakPolarHBondContact O-CB 3.43Å; D685-I689 VanDerWaalsContact O-CG1 3.3Å; D685-I689 WeakPolarHBondContact O-CG1 3.37Å; D685-I689 PolarHBondContact O-N 2.99Å; R686-I689 PolarHBondContact O-N 3.26Å; I689-T691 VanDerWaalsContact C-N 3.3Å; I689-T691 PolarHBondContact O-N 3.26Å; I689-N692 PolarHBondContact O-N 3.03Å; I689-N692 VanDerWaalsContact O-N 3.09Å
690L92.6Very high94.5Very high82 Ų8232.1 Ų32.143%0.42917%0.171SC..Hα-helixtrans-58.9-43177.9-179.481.1000112R686 C688 N692 V878 V880R686-L690 VanDerWaalsContact O-CB 3.31Å; R686-L690 WeakPolarHBondContact O-CB 3.34Å; R686-L690 PolarHBondContact O-N 3.1Å; C688-L690 PolarHBondContact O-N 3.37Å; L690-N692 PolarHBondContact O-N 3.4Å; L690-V878 WeakPolarHBondContact CD1-O 3.39Å; L690-V878 HydrophobicContact CD2-CB 3.96Å; L690-V878 HydrophobicContact CD2-CG1 3.81Å; L690-V878 WeakPolarHBondContact CD2-O 3.44Å; L690-V878 WeakPolarHBondContact CG-O 2.98Å; L690-V880 HydrophobicContact CD2-CB 4.47Å; L690-V880 HydrophobicContact CD2-CG2 3.92Å
691T93.6Very high94.5Very high23 Ų2332.2 Ų32.214%0.14117%0.171CC..THydrogen-bonded Turntrans-82.46.6-178.162.20000113T687 C688 I689 G693 K694 T695 V880T687-T691 WeakPolarHBondContact O-CB 3.41Å; T687-T691 VanDerWaalsContact O-CG2 3.28Å; T687-T691 WeakPolarHBondContact O-CG2 3.19Å; T687-T691 PolarHBondContact O-N 3.28Å; T687-T691 VanDerWaalsContact O-N 3.15Å; T687-T691 PolarHBondContact O-OG1 3.31Å; C688-T691 CarbonylContact O-C 3.43Å; C688-T691 PolarHBondContact O-N 3.46Å; C688-T691 PolarHBondContact O-OG1 2.97Å; I689-T691 VanDerWaalsContact C-N 3.3Å; I689-T691 PolarHBondContact O-N 3.26Å; T691-G693 PolarHBondContact O-N 2.98Å; T691-K694 WeakPolarHBondContact O-CB 3.47Å; T691-K694 VanDerWaalsContact O-CG 3.31Å; T691-K694 WeakPolarHBondContact O-CG 3.34Å; T691-K694 PolarHBondContact O-N 2.83Å; T691-T695 PolarHBondContact OG1-N 2.96Å; T691-V880 HydrophobicContact CG2-CB 4.41Å; T691-V880 HydrophobicContact CG2-CG2 3.92Å
692N93.8Very high94.6Very high111 Ų11133 Ų3359%0.59417%0.174SC*.THydrogen-bonded Turntrans47.843.8-174.8-167.822.2000112.6N657 C688 I689 L690 K694N657-N692 PolarHBondContact ND2-OD1 3.42Å; N657-N692 VanDerWaalsContact ND2-OD1 3.11Å; C688-N692 PolarHBondContact O-N 2.01Å; I689-N692 PolarHBondContact O-N 3.03Å; I689-N692 VanDerWaalsContact O-N 3.09Å; L690-N692 PolarHBondContact O-N 3.4Å; N692-K694 PolarHBondContact O-N 3.44Å
693G92.9Very high94.6Very high21 Ų2133 Ų3322%0.21617%0.174CC..THydrogen-bonded Turntrans87-9.5179.800000116.1C688 T691 T695C688-G693 PolarHBondContact O-N 2.97Å; T691-G693 PolarHBondContact O-N 2.98Å; G693-T695 PolarHBondContact O-N 3.28Å
694K90.2Very high94.7Very high191 Ų19133 Ų3383%0.8317%0.174SC*.THydrogen-bonded Turntrans-62-32179.3-65.9176.5-179.9-1790112.6T691 N692T691-K694 WeakPolarHBondContact O-CB 3.47Å; T691-K694 VanDerWaalsContact O-CG 3.31Å; T691-K694 WeakPolarHBondContact O-CG 3.34Å; T691-K694 PolarHBondContact O-N 2.83Å; N692-K694 PolarHBondContact O-N 3.44Å
695T89.4Confident94.7Very high33 Ų3333.1 Ų33.120%0.20218%0.175CC..THydrogen-bonded Turntrans-118.277.1174.4-54.70000110.3T687 C688 T691 G693 K697T687-T695 HydrophobicContact CG2-CG2 3.82Å; C688-T695 WeakPolarHBondContact CA-O 3.12Å; T691-T695 PolarHBondContact OG1-N 2.96Å; G693-T695 PolarHBondContact O-N 3.28Å; T695-K697 PolarHBondContact O-N 3.3Å
696A90.7Very high94.7Very high52 Ų5234 Ų3443%0.4318%0.181SC..  trans-95.456.3175.100000111.9
697K91.9Very high94.8Very high96 Ų9634.4 Ų34.442%0.41718%0.184SC..  trans-112.6150.8178.9-67.6-172.3178.3-176.40111.3T695 T734 Y770T695-K697 PolarHBondContact O-N 3.3Å; K697-T734 HydrophobicContact CB-CG2 4.25Å; K697-T734 HydrophobicContact CD-CG2 3.81Å; K697-Y770 PolarHBondContact NZ-OH 3.41Å
698F96Very high94.8Very high26 Ų2634.6 Ų34.611%0.11419%0.186CC..  trans-69.7135.8167.8-72.8-63.7000110.5L661 I664 T734 G735 L737L661-F698 HydrophobicContact CD1-CD1 3.81Å; L661-F698 HydrophobicContact CD1-CD2 4.44Å; L661-F698 HydrophobicContact CD1-CE1 3.57Å; L661-F698 HydrophobicContact CD1-CE2 4.23Å; L661-F698 HydrophobicContact CD1-CG 4.25Å; L661-F698 HydrophobicContact CD1-CZ 3.8Å; I664-F698 HydrophobicContact CB-CZ 4.04Å; I664-F698 HydrophobicContact CD1-CE2 3.98Å; I664-F698 HydrophobicContact CD1-CZ 3.5Å; I664-F698 HydrophobicContact CG1-CZ 4.35Å; I664-F698 HydrophobicContact CG2-CE1 4.48Å; I664-F698 HydrophobicContact CG2-CZ 3.81Å; F698-T734 CarbonylContact O-C 3.43Å; F698-T734 WeakPolarHBondContact O-CA 3.15Å; F698-G735 PolarHBondContact O-N 2.89Å; F698-L737 HydrophobicContact CE2-CG 4.33Å
699L97Very high94.4Very high4 Ų443.6 Ų43.62%0.02123%0.225CC..BIsolated β-bridgetrans-85.7148159.7-65.1179.5000109.6M683 S684 D701 W727 I732 H779M683-L699 HydrophobicContact CB-CD1 3.53Å; S684-L699 PolarHBondContact OG-N 3.48Å; L699-D701 PolarHBondContact O-N 2.93Å; L699-W727 HydrophobicContact CD1-CZ2 3.94Å; L699-I732 HydrophobicContact CB-CG2 3.83Å; L699-H779 HydrophobicContact CD2-CB 3.91Å
700S97.8Very high93.8Very high0 Ų048.4 Ų48.40%025%0.251CS..  trans-79.4106.9-167.7-175.50000113.3E702 D703 L704 P733 K745S700-E702 VanDerWaalsContact C-N 3.26Å; S700-E702 WeakPolarHBondContact OG-CB 3.33Å; S700-E702 PolarHBondContact OG-N 3.38Å; S700-D703 PolarHBondContact O-N 2.9Å; S700-D703 PolarHBondContact OG-N 2.84Å; S700-L704 PolarHBondContact O-N 3.26Å; S700-P733 VanDerWaalsContact CB-O 3.26Å; S700-P733 WeakPolarHBondContact CB-O 3.05Å; S700-P733 PolarHBondContact N-O 3.34Å; S700-K745 WeakPolarHBondContact CB-O 3.34Å; S700-K745 WeakPolarHBondContact OG-CB 3.03Å; S700-K745 PolarHBondContact OG-O 3.44Å
701D97Very high93.6Very high3 Ų344.5 Ų44.52%0.01623%0.23CC..Hα-helixtrans-64-30.616339.6-108.9000112.2K666 V677 A680 L699 L704 L705 Y747K666-D701 IonicContact NZ-OD1 3.8Å; K666-D701 PolarHBondContact NZ-OD1 2.9Å; V677-D701 HydrophobicContact CG2-CB 4.23Å; A680-D701 HydrophobicContact CB-CB 3.79Å; L699-D701 PolarHBondContact O-N 2.93Å; D701-L704 PolarHBondContact O-N 3.32Å; D701-L705 WeakPolarHBondContact O-CB 3.2Å; D701-L705 PolarHBondContact O-N 3.01Å; D701-Y747 WeakPolarHBondContact OD2-CB 3.3Å; D701-Y747 WeakPolarHBondContact OD2-CD2 3.12Å
702E97.4Very high93.2Very high20 Ų2043.9 Ų43.99%0.09323%0.229CC..Hα-helixtrans-60.4-42.4173-175.473.7-16000112.7S700 L705 S706 K745 S748 P760S700-E702 VanDerWaalsContact C-N 3.26Å; S700-E702 WeakPolarHBondContact OG-CB 3.33Å; S700-E702 PolarHBondContact OG-N 3.38Å; E702-L705 PolarHBondContact O-N 3.34Å; E702-S706 VanDerWaalsContact O-CB 3.3Å; E702-S706 WeakPolarHBondContact O-CB 3.01Å; E702-S706 PolarHBondContact O-N 3.27Å; E702-S706 PolarHBondContact O-OG 3.25Å; E702-K745 HydrophobicContact CB-CB 4.35Å; E702-K745 HydrophobicContact CG-CB 4.48Å; E702-S748 VanDerWaalsContact CD-OG 3.3Å; E702-S748 PolarHBondContact OE1-OG 3.35Å; E702-S748 VanDerWaalsContact OE1-OG 3.08Å; E702-S748 WeakPolarHBondContact OE2-CB 3.38Å; E702-S748 PolarHBondContact OE2-N 3.02Å; E702-S748 PolarHBondContact OE2-OG 3.43Å; E702-P760 WeakPolarHBondContact OE1-CB 3.42Å; E702-P760 WeakPolarHBondContact OE1-CG 3.39Å
703D97.8Very high92.9Very high0 Ų043.7 Ų43.70%023%0.228CC..Hα-helixtrans-66.4-43.6177.1-165.171000111.3S700 L705 C707 P733 K745 R778S700-D703 PolarHBondContact O-N 2.9Å; S700-D703 PolarHBondContact OG-N 2.84Å; D703-L705 PolarHBondContact O-N 3.26Å; D703-C707 WeakPolarHBondContact O-CA 3.43Å; D703-C707 VanDerWaalsContact O-CB 3.25Å; D703-C707 WeakPolarHBondContact O-CB 3.22Å; D703-C707 PolarHBondContact O-N 2.89Å; D703-P733 HydrophobicContact CB-CG 3.78Å; D703-P733 VanDerWaalsContact CG-CD 3.44Å; D703-P733 WeakPolarHBondContact OD2-CD 3.49Å; D703-K745 HydrophobicContact CB-CD 3.94Å; D703-K745 IonicContact OD1-NZ 3.98Å; D703-K745 PolarHBondContact OD1-NZ 2.95Å; D703-R778 IonicContact OD1-NH1 3.11Å; D703-R778 IonicContact OD1-NH2 3.11Å; D703-R778 PolarHBondContact OD1-NH2 3.49Å; D703-R778 IonicContact OD2-CZ 2.66Å; D703-R778 IonicContact OD2-NH1 3.86Å; D703-R778 PolarHBondContact OD2-NH1 3.48Å; D703-R778 IonicContact OD2-NH2 3.99Å
704L96.9Very high92.9Very high0 Ų042.8 Ų42.80%022%0.219CC..Hα-helixtrans-57.6-49.9172.6-79.2174000111.1W675 A676 A679 A680 M683 S700 D701 S706 C708 A723 Y726 I732W675-L704 HydrophobicContact CZ3-CB 4.44Å; A676-L704 HydrophobicContact CB-CB 3.93Å; A679-L704 HydrophobicContact CB-CD1 4.23Å; A680-L704 HydrophobicContact CB-CD1 4.09Å; M683-L704 HydrophobicContact CE-CD1 4.1Å; M683-L704 HydrophobicContact SD-CD1 4.3Å; S700-L704 PolarHBondContact O-N 3.26Å; D701-L704 PolarHBondContact O-N 3.32Å; L704-S706 PolarHBondContact O-N 3.01Å; L704-C708 VanDerWaalsContact O-CB 3.29Å; L704-C708 WeakPolarHBondContact O-CB 3.29Å; L704-C708 PolarHBondContact O-N 3.09Å; L704-A723 HydrophobicContact CD1-CB 4.09Å; L704-A723 HydrophobicContact CD2-CB 3.7Å; L704-A723 HydrophobicContact CG-CB 4.49Å; L704-Y726 HydrophobicContact CD2-CD1 3.96Å; L704-I732 HydrophobicContact CD2-CD1 3.57Å; L704-I732 HydrophobicContact CD2-CG1 4.44Å; L704-I732 HydrophobicContact CG-CD1 3.71Å; L704-I732 HydrophobicContact CG-CG1 4.45Å
705L96Very high93Very high5 Ų533.9 Ų33.93%0.02618%0.18CC..Hα-helixtrans-63.4-42.7-176-177.770000112.9W675 A676 D701 E702 D703 Y747 F749 P760W675-L705 HydrophobicContact CZ2-CD1 4.16Å; A676-L705 HydrophobicContact CB-CB 4.48Å; D701-L705 WeakPolarHBondContact O-CB 3.2Å; D701-L705 PolarHBondContact O-N 3.01Å; E702-L705 PolarHBondContact O-N 3.34Å; D703-L705 PolarHBondContact O-N 3.26Å; L705-Y747 HydrophobicContact CD2-CE2 4.2Å; L705-F749 HydrophobicContact CD2-CE2 3.7Å; L705-P760 HydrophobicContact CD2-CG 4.46Å
706S96.2Very high93Very high19 Ų1937.7 Ų37.713%0.13320%0.2CC..Hα-helixtrans-93.7-33.2-171.361.30000113.6E702 L704 P760 C762E702-S706 VanDerWaalsContact O-CB 3.3Å; E702-S706 WeakPolarHBondContact O-CB 3.01Å; E702-S706 PolarHBondContact O-N 3.27Å; E702-S706 PolarHBondContact O-OG 3.25Å; L704-S706 PolarHBondContact O-N 3.01Å; S706-P760 VanDerWaalsContact CB-O 3.3Å; S706-P760 WeakPolarHBondContact CB-O 3.18Å; S706-C762 VanDerWaalsContact O-CB 3.31Å; S706-C762 WeakPolarHBondContact O-CB 3.27Å
707C96.5Very high93Very high13 Ų1335.3 Ų35.39%0.08818%0.18CC..Hα-helixtrans-110.7-20-168.7-65.60000115.2D703 K709 K745 C762D703-C707 WeakPolarHBondContact O-CA 3.43Å; D703-C707 VanDerWaalsContact O-CB 3.25Å; D703-C707 WeakPolarHBondContact O-CB 3.22Å; D703-C707 PolarHBondContact O-N 2.89Å; C707-K709 PolarHBondContact O-N 2.89Å; C707-K709 VanDerWaalsContact O-N 3.1Å; C707-K745 PolarHBondContact SG-NZ 3.04Å; C707-K745 VanDerWaalsContact SG-NZ 3.44Å; C707-C762 VanDerWaalsContact CA-SG 3.52Å; C707-C762 HydrophobicContact CB-CB 3.95Å; C707-C762 WeakPolarHBondContact CB-SG 3.17Å; C707-C762 WeakPolarHBondContact SG-CA 3.47Å; C707-C762 WeakPolarHBondContact SG-CB 3.37Å; C707-C762 CovalentContact SG-SG 2.04Å; C707-C762 PolarHBondContact SG-SG 3.09Å
708C94.1Very high92.7Very high8 Ų830.8 Ų30.85%0.05416%0.16CC..  trans-82.690.1179.6-175.20000112.2L704 N710 C711 Y726L704-C708 VanDerWaalsContact O-CB 3.29Å; L704-C708 WeakPolarHBondContact O-CB 3.29Å; L704-C708 PolarHBondContact O-N 3.09Å; C708-N710 VanDerWaalsContact C-N 3.26Å; C708-N710 PolarHBondContact O-N 2.89Å; C708-C711 HydrophobicContact CB-CB 3.64Å; C708-C711 WeakPolarHBondContact CB-SG 3.45Å; C708-C711 PolarHBondContact O-N 3.3Å; C708-C711 VanDerWaalsContact O-N 3.16Å; C708-C711 WeakPolarHBondContact SG-CB 3.48Å; C708-C711 PolarHBondContact SG-N 3.41Å; C708-C711 CovalentContact SG-SG 2.01Å; C708-C711 PolarHBondContact SG-SG 2.92Å; C708-Y726 HydrophobicContact CB-CD1 4.25Å; C708-Y726 HydrophobicContact CB-CD2 3.8Å; C708-Y726 HydrophobicContact CB-CE1 4.46Å; C708-Y726 HydrophobicContact CB-CE2 4.04Å; C708-Y726 HydrophobicContact CB-CG 3.9Å; C708-Y726 VanDerWaalsContact SG-CB 3.59Å; C708-Y726 WeakPolarHBondContact SG-CD2 3.06Å; C708-Y726 VanDerWaalsContact SG-CG 3.6Å
709K87.5Confident92.2Very high189 Ų18929.9 Ų29.982%0.82216%0.157SC*.THydrogen-bonded Turntrans-63.1-29.1-179.6-62.1-174.9-179.6-178.80114.2C707C707-K709 PolarHBondContact O-N 2.89Å; C707-K709 VanDerWaalsContact O-N 3.1Å
710N85.5Confident91.8Very high120 Ų12029.7 Ų29.764%0.64216%0.156SC*.THydrogen-bonded Turntrans-90.5-4.9-179.7-60.3-1000112.5C708 M722C708-N710 VanDerWaalsContact C-N 3.26Å; C708-N710 PolarHBondContact O-N 2.89Å; N710-M722 HydrophobicContact CB-CE 3.72Å; N710-M722 WeakPolarHBondContact O-CB 3.48Å; N710-M722 VanDerWaalsContact O-CE 3.28Å; N710-M722 WeakPolarHBondContact O-CE 3.48Å; N710-M722 WeakPolarHBondContact O-CG 3.26Å
711C87.2Confident91.1Very high0 Ų031 Ų310%016%0.161CC..THydrogen-bonded Turntrans-82.3-25.6179.1-64.70000112.9W675 C708 G718 N719 M722 A723W675-C711 HydrophobicContact CE3-CB 4.17Å; W675-C711 HydrophobicContact CH2-CB 3.57Å; W675-C711 HydrophobicContact CZ3-CB 3.3Å; C708-C711 HydrophobicContact CB-CB 3.64Å; C708-C711 WeakPolarHBondContact CB-SG 3.45Å; C708-C711 PolarHBondContact O-N 3.3Å; C708-C711 VanDerWaalsContact O-N 3.16Å; C708-C711 WeakPolarHBondContact SG-CB 3.48Å; C708-C711 PolarHBondContact SG-N 3.41Å; C708-C711 CovalentContact SG-SG 2.01Å; C708-C711 PolarHBondContact SG-SG 2.92Å; C711-G718 CarbonylContact O-C 3.59Å; C711-G718 WeakPolarHBondContact O-CA 3.49Å; C711-N719 PolarHBondContact O-N 3.31Å; C711-M722 HydrophobicContact CB-CB 4.21Å; C711-M722 PolarHBondContact SG-O 2.98Å; C711-M722 VanDerWaalsContact SG-O 3.38Å; C711-A723 WeakPolarHBondContact SG-CA 3.26Å; C711-A723 PolarHBondContact SG-N 3.46Å; C711-A723 VanDerWaalsContact SG-N 3.39Å
712G85Confident90.6Very high10 Ų1032.8 Ų32.810%0.10317%0.17CC..BIsolated β-bridgetrans145.1-161.2-178.100000112.2G714 G717G712-G714 PolarHBondContact O-N 3.01Å; G712-G717 CarbonylContact C-O 3.46Å
713N88.5Confident90.3Very high107 Ų10731.9 Ų31.957%0.57217%0.166SC*.SBendtrans-98.735.6-172.6-67.5-44.7000112.8C715 N716 G717 T759N713-C715 PolarHBondContact O-N 2.8Å; N713-N716 HydrophobicContact CB-CB 4Å; N713-N716 PolarHBondContact O-N 2.64Å; N713-N716 VanDerWaalsContact O-N 3.13Å; N713-G717 PolarHBondContact N-O 2.93Å; N713-T759 PolarHBondContact O-OG1 3.11Å
714G91.6Very high89.9Confident3 Ų331.9 Ų31.93%0.03117%0.166CC..G310 helixtrans62.1-119.517800000113W675 G712 N716 G717W675-G714 PolarHBondContact NE1-O 2.8Å; G712-G714 PolarHBondContact O-N 3.01Å; G714-N716 PolarHBondContact O-N 3.15Å; G714-G717 PolarHBondContact O-N 3.04Å; G714-G717 VanDerWaalsContact O-N 3.13Å
715C92.6Very high89.4Confident3 Ų333 Ų332%0.0217%0.172CC..G310 helixtrans-67.3-11.5177.7-72.30000114.5C671 G672 N713 G717 T759C671-C715 HydrophobicContact CB-CB 4.04Å; C671-C715 WeakPolarHBondContact CB-SG 3.3Å; C671-C715 WeakPolarHBondContact SG-CA 3.5Å; C671-C715 WeakPolarHBondContact SG-CB 3.23Å; C671-C715 CovalentContact SG-SG 2.04Å; C671-C715 PolarHBondContact SG-SG 3.14Å; G672-C715 VanDerWaalsContact CA-O 3.29Å; G672-C715 WeakPolarHBondContact CA-O 3.4Å; G672-C715 PolarHBondContact N-O 3.15Å; N713-C715 PolarHBondContact O-N 2.8Å; C715-G717 VanDerWaalsContact C-N 3.29Å; C715-T759 PolarHBondContact N-OG1 3.48Å
716N89.7Confident89.2Confident114 Ų11434.7 Ų34.761%0.6118%0.178SC*.G310 helixtrans-91.98.6174.2-60.7-45.9000112.7N713 G714N713-N716 HydrophobicContact CB-CB 4Å; N713-N716 PolarHBondContact O-N 2.64Å; N713-N716 VanDerWaalsContact O-N 3.13Å; G714-N716 PolarHBondContact O-N 3.15Å
717G89.9Confident89.1Confident2 Ų233.8 Ų33.82%0.02117%0.172CC..  trans109.5164.117300000114.1G621 G712 N713 G714 C715G621-G717 CarbonylContact O-C 3.56Å; G621-G717 WeakPolarHBondContact O-CA 3.25Å; G712-G717 CarbonylContact C-O 3.46Å; N713-G717 PolarHBondContact N-O 2.93Å; G714-G717 PolarHBondContact O-N 3.04Å; G714-G717 VanDerWaalsContact O-N 3.13Å; C715-G717 VanDerWaalsContact C-N 3.29Å
718G86.9Confident88.7Confident0 Ų037.3 Ų37.30%019%0.186CC..BIsolated β-bridgetrans-175.3-172.9-175.400000112.2G621 V622 S623 C711G621-G718 PolarHBondContact O-N 2.61Å; V622-G718 WeakPolarHBondContact CA-O 3.46Å; S623-G718 PolarHBondContact N-O 2.85Å; C711-G718 CarbonylContact O-C 3.59Å; C711-G718 WeakPolarHBondContact O-CA 3.49Å
719N85.3Confident88.5Confident7 Ų741.6 Ų41.64%0.03721%0.208CC..  trans-122.2123.4-170.2-171.2-54000110.9C711 F721 M722 A723C711-N719 PolarHBondContact O-N 3.31Å; N719-F721 VanDerWaalsContact C-N 3.28Å; N719-F721 PolarHBondContact O-N 3.31Å; N719-F721 WeakPolarHBondContact OD1-CA 3.49Å; N719-F721 WeakPolarHBondContact OD1-CB 3.45Å; N719-F721 PolarHBondContact OD1-N 2.74Å; N719-M722 HydrophobicContact CB-CB 4.36Å; N719-M722 HydrophobicContact CB-CG 4.15Å; N719-M722 PolarHBondContact O-N 3.33Å; N719-A723 PolarHBondContact O-N 3.16Å
720P87.8Confident88.7Confident0 Ų035.1 Ų35.10%019%0.185CC..Hα-helixtrans-58.6-34.7178-23.432.3000114.3W675 A723 L724 I805 I807 A834W675-P720 HydrophobicContact CB-CG 3.9Å; P720-A723 VanDerWaalsContact O-CB 3.3Å; P720-A723 WeakPolarHBondContact O-CB 3.17Å; P720-A723 PolarHBondContact O-N 2.82Å; P720-L724 WeakPolarHBondContact O-CG 3.47Å; P720-L724 PolarHBondContact O-N 2.95Å; P720-I805 HydrophobicContact CB-CD1 4.42Å; P720-I805 HydrophobicContact CB-CG2 3.97Å; P720-I805 HydrophobicContact CG-CG2 4.33Å; P720-I807 HydrophobicContact CG-CD1 3.92Å; P720-I807 HydrophobicContact CG-CG1 4.09Å; P720-A834 HydrophobicContact CG-CB 3.83Å
721F84.1Confident89.1Confident28 Ų2829.4 Ų29.412%0.12315%0.154CC..Hα-helixtrans-63.9-45.4179175.3-105.1000111.5M634 N719 A723 L724 L725 V784M634-F721 HydrophobicContact CG-CE2 3.97Å; M634-F721 HydrophobicContact CG-CZ 4.36Å; M634-F721 HydrophobicContact SD-CD2 4.01Å; M634-F721 HydrophobicContact SD-CE2 3.84Å; M634-F721 HydrophobicContact SD-CZ 4.5Å; N719-F721 VanDerWaalsContact C-N 3.28Å; N719-F721 PolarHBondContact O-N 3.31Å; N719-F721 WeakPolarHBondContact OD1-CA 3.49Å; N719-F721 WeakPolarHBondContact OD1-CB 3.45Å; N719-F721 PolarHBondContact OD1-N 2.74Å; F721-A723 PolarHBondContact O-N 3.31Å; F721-L724 WeakPolarHBondContact O-CA 3.42Å; F721-L724 WeakPolarHBondContact O-CB 3.13Å; F721-L724 PolarHBondContact O-N 2.68Å; F721-L725 HydrophobicContact CD1-CD1 3.98Å; F721-L725 HydrophobicContact CD1-CG 4.37Å; F721-L725 HydrophobicContact CE1-CD1 3.38Å; F721-L725 HydrophobicContact CE1-CG 3.94Å; F721-L725 HydrophobicContact CE2-CG 4.47Å; F721-L725 HydrophobicContact CZ-CD1 3.8Å; F721-L725 HydrophobicContact CZ-CD2 4.16Å; F721-L725 HydrophobicContact CZ-CG 3.98Å; F721-L725 PolarHBondContact O-N 2.91Å; F721-V784 HydrophobicContact CD2-CG1 4.48Å; F721-V784 HydrophobicContact CE2-CG1 4.22Å
722M86.1Confident89.6Confident41 Ų4129.4 Ų29.420%0.20215%0.154CC..Hα-helixtrans-62.9-32.8175.3-65.2-55.3-71.500111.8N710 C711 N719 L725 Y726N710-M722 HydrophobicContact CB-CE 3.72Å; N710-M722 WeakPolarHBondContact O-CB 3.48Å; N710-M722 VanDerWaalsContact O-CE 3.28Å; N710-M722 WeakPolarHBondContact O-CE 3.48Å; N710-M722 WeakPolarHBondContact O-CG 3.26Å; C711-M722 HydrophobicContact CB-CB 4.21Å; C711-M722 PolarHBondContact SG-O 2.98Å; C711-M722 VanDerWaalsContact SG-O 3.38Å; N719-M722 HydrophobicContact CB-CB 4.36Å; N719-M722 HydrophobicContact CB-CG 4.15Å; N719-M722 PolarHBondContact O-N 3.33Å; M722-L725 PolarHBondContact O-N 3.23Å; M722-L725 HydrophobicContact SD-CD1 3.89Å; M722-Y726 WeakPolarHBondContact O-CB 3.45Å; M722-Y726 PolarHBondContact O-N 3.43Å
723A91.9Very high90.2Very high0 Ų029 Ų290%015%0.149CC..Hα-helixtrans-63.6-40.1171.300000112.4W675 A679 M683 L704 C711 N719 P720 F721 Y726 W727W675-A723 HydrophobicContact CE3-CB 4.14Å; W675-A723 HydrophobicContact CZ3-CB 4.14Å; A679-A723 HydrophobicContact CB-CB 3.9Å; M683-A723 WeakPolarHBondContact CE-O 3.2Å; L704-A723 HydrophobicContact CD1-CB 4.09Å; L704-A723 HydrophobicContact CD2-CB 3.7Å; L704-A723 HydrophobicContact CG-CB 4.49Å; C711-A723 WeakPolarHBondContact SG-CA 3.26Å; C711-A723 PolarHBondContact SG-N 3.46Å; C711-A723 VanDerWaalsContact SG-N 3.39Å; N719-A723 PolarHBondContact O-N 3.16Å; P720-A723 VanDerWaalsContact O-CB 3.3Å; P720-A723 WeakPolarHBondContact O-CB 3.17Å; P720-A723 PolarHBondContact O-N 2.82Å; F721-A723 PolarHBondContact O-N 3.31Å; A723-Y726 PolarHBondContact O-N 3.23Å; A723-W727 PolarHBondContact O-N 3.43Å
724L88.6Confident90.6Very high0 Ų023.9 Ų23.90%012%0.122CC..Hα-helixtrans-65.1-43173.6-60.8-174.3000112.1M683 P720 F721 Y726 W727 K728 V784 I805 C874 L876M683-L724 HydrophobicContact CE-CD2 3.62Å; P720-L724 WeakPolarHBondContact O-CG 3.47Å; P720-L724 PolarHBondContact O-N 2.95Å; F721-L724 WeakPolarHBondContact O-CA 3.42Å; F721-L724 WeakPolarHBondContact O-CB 3.13Å; F721-L724 PolarHBondContact O-N 2.68Å; L724-Y726 VanDerWaalsContact C-N 3.33Å; L724-Y726 PolarHBondContact O-N 2.97Å; L724-W727 WeakPolarHBondContact O-CB 3.47Å; L724-W727 PolarHBondContact O-N 3.1Å; L724-W727 VanDerWaalsContact O-N 3.12Å; L724-K728 PolarHBondContact O-N 2.9Å; L724-V784 HydrophobicContact CB-CB 4.4Å; L724-V784 HydrophobicContact CB-CG1 3.41Å; L724-V784 VanDerWaalsContact CB-CG1 3.41Å; L724-V784 HydrophobicContact CB-CG2 4.07Å; L724-V784 HydrophobicContact CD1-CG1 3.98Å; L724-V784 HydrophobicContact CG-CG1 4.35Å; L724-V784 WeakPolarHBondContact O-CG2 3.33Å; L724-I805 HydrophobicContact CD1-CD1 4.17Å; L724-I805 HydrophobicContact CD2-CD1 3.68Å; L724-I805 HydrophobicContact CG-CD1 4.1Å; L724-C874 HydrophobicContact CD1-CB 3.83Å; L724-L876 HydrophobicContact CB-CD2 4.38Å; L724-L876 HydrophobicContact CD1-CD1 4.42Å; L724-L876 HydrophobicContact CD1-CD2 4.46Å; L724-L876 HydrophobicContact CD1-CG 4.22Å; L724-L876 HydrophobicContact CD2-CD1 3.39Å; L724-L876 HydrophobicContact CD2-CD2 4.06Å; L724-L876 HydrophobicContact CD2-CG 3.92Å; L724-L876 HydrophobicContact CG-CD1 4.47Å
725L86.8Confident90.8Very high25 Ų2523.9 Ų23.913%0.13112%0.122CC..Hα-helixtrans-61.9-41175.4-72.5-178.3000112.1F721 M722 W727 K728 N729 V784F721-L725 HydrophobicContact CD1-CD1 3.98Å; F721-L725 HydrophobicContact CD1-CG 4.37Å; F721-L725 HydrophobicContact CE1-CD1 3.38Å; F721-L725 HydrophobicContact CE1-CG 3.94Å; F721-L725 HydrophobicContact CE2-CG 4.47Å; F721-L725 HydrophobicContact CZ-CD1 3.8Å; F721-L725 HydrophobicContact CZ-CD2 4.16Å; F721-L725 HydrophobicContact CZ-CG 3.98Å; F721-L725 PolarHBondContact O-N 2.91Å; M722-L725 PolarHBondContact O-N 3.23Å; M722-L725 HydrophobicContact SD-CD1 3.89Å; L725-W727 VanDerWaalsContact C-N 3.27Å; L725-W727 PolarHBondContact O-N 3.37Å; L725-K728 PolarHBondContact O-N 2.94Å; L725-N729 WeakPolarHBondContact O-CB 3.29Å; L725-N729 PolarHBondContact O-N 3.35Å; L725-N729 PolarHBondContact O-ND2 3.49Å; L725-V784 HydrophobicContact CD2-CG1 4.33Å
726Y91.7Very high90.9Very high39 Ų3923.7 Ų23.715%0.15312%0.121CC..Hα-helixtrans-62.1-37.2173.9-174-92.2000111.7L704 C708 M722 A723 L724 T730 G731 I732L704-Y726 HydrophobicContact CD2-CD1 3.96Å; C708-Y726 HydrophobicContact CB-CD1 4.25Å; C708-Y726 HydrophobicContact CB-CD2 3.8Å; C708-Y726 HydrophobicContact CB-CE1 4.46Å; C708-Y726 HydrophobicContact CB-CE2 4.04Å; C708-Y726 HydrophobicContact CB-CG 3.9Å; C708-Y726 VanDerWaalsContact SG-CB 3.59Å; C708-Y726 WeakPolarHBondContact SG-CD2 3.06Å; C708-Y726 VanDerWaalsContact SG-CG 3.6Å; M722-Y726 WeakPolarHBondContact O-CB 3.45Å; M722-Y726 PolarHBondContact O-N 3.43Å; A723-Y726 PolarHBondContact O-N 3.23Å; L724-Y726 VanDerWaalsContact C-N 3.33Å; L724-Y726 PolarHBondContact O-N 2.97Å; Y726-T730 WeakPolarHBondContact CD2-OG1 2.88Å; Y726-T730 HydrophobicContact CE1-CG2 4.17Å; Y726-T730 HydrophobicContact CE2-CG2 4.05Å; Y726-T730 WeakPolarHBondContact CE2-OG1 3.17Å; Y726-T730 WeakPolarHBondContact O-CA 3.04Å; Y726-T730 VanDerWaalsContact O-CB 3.28Å; Y726-T730 WeakPolarHBondContact O-CB 3.37Å; Y726-T730 PolarHBondContact O-N 3.46Å; Y726-G731 PolarHBondContact O-N 3.21Å; Y726-G731 VanDerWaalsContact O-N 3.17Å; Y726-I732 HydrophobicContact CD1-CD1 3.48Å; Y726-I732 VanDerWaalsContact CD1-CD1 3.48Å; Y726-I732 HydrophobicContact CE1-CD1 3.63Å
727W93.3Very high91.2Very high1 Ų121.7 Ų21.70%0.00411%0.11CC..Hα-helixtrans-64.5-40.7174.2-175.333.6000113.3M683 L699 A723 L724 L725 G731 I732 H779 K780 A781 L876 V878M683-W727 HydrophobicContact CB-CD2 4.14Å; M683-W727 HydrophobicContact CB-CE3 4.07Å; M683-W727 HydrophobicContact CB-CH2 3.85Å; M683-W727 HydrophobicContact CB-CZ2 3.93Å; M683-W727 HydrophobicContact CB-CZ3 3.95Å; M683-W727 HydrophobicContact CE-CB 3.58Å; M683-W727 HydrophobicContact CE-CD2 4.18Å; M683-W727 HydrophobicContact CE-CE3 4.16Å; M683-W727 HydrophobicContact CE-CG 4Å; M683-W727 HydrophobicContact CG-CD2 3.64Å; M683-W727 HydrophobicContact CG-CE3 3.4Å; M683-W727 VanDerWaalsContact CG-CE3 3.4Å; M683-W727 HydrophobicContact CG-CG 4.3Å; M683-W727 HydrophobicContact CG-CH2 4.1Å; M683-W727 HydrophobicContact CG-CZ2 4.33Å; M683-W727 HydrophobicContact CG-CZ3 3.69Å; M683-W727 HydrophobicContact SD-CB 3.94Å; M683-W727 HydrophobicContact SD-CD2 3.75Å; M683-W727 HydrophobicContact SD-CE3 4.03Å; M683-W727 HydrophobicContact SD-CG 3.74Å; L699-W727 HydrophobicContact CD1-CZ2 3.94Å; A723-W727 PolarHBondContact O-N 3.43Å; L724-W727 WeakPolarHBondContact O-CB 3.47Å; L724-W727 PolarHBondContact O-N 3.1Å; L724-W727 VanDerWaalsContact O-N 3.12Å; L725-W727 VanDerWaalsContact C-N 3.27Å; L725-W727 PolarHBondContact O-N 3.37Å; W727-G731 VanDerWaalsContact O-CA 3.25Å; W727-G731 WeakPolarHBondContact O-CA 3.3Å; W727-G731 PolarHBondContact O-N 2.82Å; W727-G731 VanDerWaalsContact O-N 3.14Å; W727-I732 HydrophobicContact CB-CG1 3.98Å; W727-I732 HydrophobicContact CG-CG1 3.98Å; W727-H779 PolarHBondContact NE1-O 2.73Å; W727-K780 WeakPolarHBondContact O-CA 3.42Å; W727-A781 HydrophobicContact CD2-CB 3.66Å; W727-A781 HydrophobicContact CE3-CB 3.48Å; W727-A781 VanDerWaalsContact CE3-CB 3.48Å; W727-A781 HydrophobicContact CG-CB 4.2Å; W727-A781 HydrophobicContact CH2-CB 4.32Å; W727-A781 HydrophobicContact CZ2-CB 4.44Å; W727-A781 HydrophobicContact CZ3-CB 3.8Å; W727-A781 PolarHBondContact O-N 3.16Å; W727-L876 HydrophobicContact CE3-CD1 3.67Å; W727-L876 HydrophobicContact CE3-CD2 3.44Å; W727-L876 VanDerWaalsContact CE3-CD2 3.44Å; W727-L876 HydrophobicContact CE3-CG 4.09Å; W727-L876 HydrophobicContact CH2-CD1 4.35Å; W727-L876 HydrophobicContact CZ3-CB 4.12Å; W727-L876 HydrophobicContact CZ3-CD1 3.23Å; W727-L876 HydrophobicContact CZ3-CD2 3.42Å; W727-L876 VanDerWaalsContact CZ3-CD2 3.42Å; W727-L876 HydrophobicContact CZ3-CG 3.71Å; W727-V878 HydrophobicContact CH2-CG1 4.3Å; W727-V878 HydrophobicContact CH2-CG2 3.57Å; W727-V878 HydrophobicContact CZ3-CG2 4.17Å
728K88.1Confident91.4Very high86 Ų8627.6 Ų27.637%0.37413%0.132SC..Hα-helixtrans-64.9-50.6174.1-177.4-177.4178.7-174.60112L724 L725 A781 V784L724-K728 PolarHBondContact O-N 2.9Å; L725-K728 PolarHBondContact O-N 2.94Å; K728-A781 HydrophobicContact CB-CB 4.27Å; K728-V784 HydrophobicContact CB-CG2 3.7Å; K728-V784 HydrophobicContact CD-CG2 4.11Å; K728-V784 HydrophobicContact CG-CG2 4.4Å
729N90.2Very high91.6Very high99 Ų9930.4 Ų30.453%0.52916%0.161SC..Hα-helixtrans-79.7-45.5-169.6-64.5-20.3000112.1L725 K780L725-N729 WeakPolarHBondContact O-CB 3.29Å; L725-N729 PolarHBondContact O-N 3.35Å; L725-N729 PolarHBondContact O-ND2 3.49Å; N729-K780 PolarHBondContact O-NZ 3.3Å
730T92.9Very high92.1Very high53 Ų5331.4 Ų31.433%0.32517%0.168SC..THydrogen-bonded Turntrans-100.8-38.8-174.2-46.40000112.5Y726 K780Y726-T730 WeakPolarHBondContact CD2-OG1 2.88Å; Y726-T730 HydrophobicContact CE1-CG2 4.17Å; Y726-T730 HydrophobicContact CE2-CG2 4.05Å; Y726-T730 WeakPolarHBondContact CE2-OG1 3.17Å; Y726-T730 WeakPolarHBondContact O-CA 3.04Å; Y726-T730 VanDerWaalsContact O-CB 3.28Å; Y726-T730 WeakPolarHBondContact O-CB 3.37Å; Y726-T730 PolarHBondContact O-N 3.46Å; T730-K780 VanDerWaalsContact O-CE 3.22Å; T730-K780 WeakPolarHBondContact O-CE 3.43Å
731G93.8Very high92.4Very high0 Ų037.4 Ų37.40%020%0.195CC..  trans83.8153.2-169.400000112.8Y726 W727 R778 H779Y726-G731 PolarHBondContact O-N 3.21Å; Y726-G731 VanDerWaalsContact O-N 3.17Å; W727-G731 VanDerWaalsContact O-CA 3.25Å; W727-G731 WeakPolarHBondContact O-CA 3.3Å; W727-G731 PolarHBondContact O-N 2.82Å; W727-G731 VanDerWaalsContact O-N 3.14Å; G731-R778 PolarHBondContact O-NH1 2.82Å; G731-H779 CarbonylContact C-O 3.49Å; G731-H779 WeakPolarHBondContact CA-O 3.39Å
732I96.6Very high92.7Very high0 Ų041 Ų410%022%0.219CC..BIsolated β-bridgetrans-114.3129.4-176.5-61.9-58.1000109.3M683 L699 L704 Y726 W727 H779M683-I732 HydrophobicContact SD-CG1 4.04Å; L699-I732 HydrophobicContact CB-CG2 3.83Å; L704-I732 HydrophobicContact CD2-CD1 3.57Å; L704-I732 HydrophobicContact CD2-CG1 4.44Å; L704-I732 HydrophobicContact CG-CD1 3.71Å; L704-I732 HydrophobicContact CG-CG1 4.45Å; Y726-I732 HydrophobicContact CD1-CD1 3.48Å; Y726-I732 VanDerWaalsContact CD1-CD1 3.48Å; Y726-I732 HydrophobicContact CE1-CD1 3.63Å; W727-I732 HydrophobicContact CB-CG1 3.98Å; W727-I732 HydrophobicContact CG-CG1 3.98Å; I732-H779 PolarHBondContact N-O 2.89Å; I732-H779 PolarHBondContact O-N 3.48Å
733P97.3Very high93.1Very high0 Ų039.1 Ų39.10%021%0.21CC..  trans-70.9165.1173.332.8-35.5000111.3S700 D703 C744 K745 I774 D777 R778S700-P733 VanDerWaalsContact CB-O 3.26Å; S700-P733 WeakPolarHBondContact CB-O 3.05Å; S700-P733 PolarHBondContact N-O 3.34Å; D703-P733 HydrophobicContact CB-CG 3.78Å; D703-P733 VanDerWaalsContact CG-CD 3.44Å; D703-P733 WeakPolarHBondContact OD2-CD 3.49Å; P733-C744 HydrophobicContact CB-CB 4.15Å; P733-K745 HydrophobicContact CG-CD 4.23Å; P733-I774 HydrophobicContact CB-CG1 3.97Å; P733-I774 HydrophobicContact CG-CD1 4.29Å; P733-I774 HydrophobicContact CG-CG1 4.19Å; P733-D777 WeakPolarHBondContact CA-O 3.09Å; P733-R778 HydrophobicContact CB-CG 4.43Å
734T97.5Very high93.4Very high1 Ų139.1 Ų39.11%0.00621%0.21CC..BIsolated β-bridgetrans-62.5149.4170.664.80000111K697 F698 G743 C744 K745 Y770 D777K697-T734 HydrophobicContact CB-CG2 4.25Å; K697-T734 HydrophobicContact CD-CG2 3.81Å; F698-T734 CarbonylContact O-C 3.43Å; F698-T734 WeakPolarHBondContact O-CA 3.15Å; T734-G743 WeakPolarHBondContact OG1-CA 3.22Å; T734-C744 WeakPolarHBondContact O-CB 3.42Å; T734-C744 PolarHBondContact O-N 3.41Å; T734-C744 VanDerWaalsContact O-N 3.07Å; T734-C744 PolarHBondContact OG1-N 3.14Å; T734-K745 PolarHBondContact O-N 3.06Å; T734-Y770 PolarHBondContact OG1-OH 2.74Å; T734-D777 WeakPolarHBondContact CA-OD2 3.47Å; T734-D777 VanDerWaalsContact CB-OD2 3.28Å; T734-D777 WeakPolarHBondContact CB-OD2 3.4Å; T734-D777 WeakPolarHBondContact CG2-OD1 3.44Å; T734-D777 WeakPolarHBondContact CG2-OD2 3.37Å; T734-D777 PolarHBondContact N-OD2 3.5Å; T734-D777 PolarHBondContact OG1-OD1 3.02Å; T734-D777 PolarHBondContact OG1-OD2 3.04Å
735G96.4Very high93.8Very high2 Ų239.6 Ų39.62%0.02121%0.212CC..EExtended strand (participates in β ladder)trans-135.4-147.7177.100000111.6F698 G743 K745F698-G735 PolarHBondContact O-N 2.89Å; G735-G743 WeakPolarHBondContact O-CA 3.19Å; G735-K745 WeakPolarHBondContact CA-O 3.44Å
736G94.5Very high94.3Very high0 Ų039.3 Ų39.30%021%0.211CC..EExtended strand (participates in β ladder)trans170.7172-177.500000111.9P746 Y747G736-P746 WeakPolarHBondContact O-CA 2.95Å; G736-Y747 PolarHBondContact O-N 2.99Å
737L95Very high94.6Very high72 Ų7238 Ų3838%0.37721%0.206SC..SBendtrans-63162.4170-57.3178.1000110.3I664 K666 F698 G739 S740I664-L737 HydrophobicContact CG2-CD1 4.17Å; I664-L737 HydrophobicContact CG2-CD2 4.18Å; K666-L737 HydrophobicContact CG-CD2 3.97Å; F698-L737 HydrophobicContact CE2-CG 4.33Å; L737-G739 PolarHBondContact O-N 2.95Å; L737-S740 WeakPolarHBondContact O-CB 3.28Å; L737-S740 PolarHBondContact O-N 2.91Å
738Y94Very high94.6Very high126 Ų12640.3 Ų40.349%0.49422%0.222SC..THydrogen-bonded Turntrans-49.7131.4172.6176-94.5000111.9S740 Y747 S748 F749 P750Y738-S740 PolarHBondContact O-N 3.46Å; Y738-Y747 VanDerWaalsContact CA-O 3.26Å; Y738-Y747 WeakPolarHBondContact CA-O 3.16Å; Y738-S748 WeakPolarHBondContact CD2-O 3Å; Y738-S748 WeakPolarHBondContact CE2-O 3.47Å; Y738-F749 VanDerWaalsContact CD2-C 3.47Å; Y738-P750 HydrophobicContact CD1-CB 4.08Å; Y738-P750 HydrophobicContact CD2-CB 4.25Å; Y738-P750 HydrophobicContact CE1-CB 3.83Å; Y738-P750 HydrophobicContact CE2-CB 4Å; Y738-P750 HydrophobicContact CE2-CG 4.17Å; Y738-P750 HydrophobicContact CG-CB 4.28Å
739G92.5Very high94.9Very high58 Ų5837.4 Ų37.460%0.59821%0.21SC*.THydrogen-bonded Turntrans77.3-2.9-177.900000115.2L737L737-G739 PolarHBondContact O-N 2.95Å
740S94.7Very high94.9Very high28 Ų2834.5 Ų34.520%0.19620%0.196CC..  trans-65.8139.4175.5-176.50000111.6L737 Y738 T742 P746L737-S740 WeakPolarHBondContact O-CB 3.28Å; L737-S740 PolarHBondContact O-N 2.91Å; Y738-S740 PolarHBondContact O-N 3.46Å; S740-T742 PolarHBondContact OG-N 3.29Å; S740-T742 PolarHBondContact OG-OG1 3.44Å; S740-P746 WeakPolarHBondContact O-CG 3.45Å
741K94.2Very high94.7Very high127 Ų12736 Ų3655%0.55221%0.207SC*.  trans-108.55.6175.7-59.9-173.2177.3-153.10113.4E769K741-E769 HydrophobicContact CB-CB 4.32Å; K741-E769 HydrophobicContact CD-CB 4.2Å; K741-E769 HydrophobicContact CD-CG 4.01Å; K741-E769 WeakPolarHBondContact CE-OE1 3.23Å; K741-E769 HydrophobicContact CG-CB 4.41Å; K741-E769 IonicContact NZ-OE1 2.68Å; K741-E769 PolarHBondContact NZ-OE1 3.2Å
742T91.5Very high94Very high103 Ų10336.9 Ų36.963%0.63222%0.216SC*.SBendtrans-94.6-0.2-171.5590000114.6S740 Y770S740-T742 PolarHBondContact OG-N 3.29Å; S740-T742 PolarHBondContact OG-OG1 3.44Å; T742-Y770 WeakPolarHBondContact O-CE2 3.22Å
743G94.3Very high93.2Very high1 Ų139.4 Ų39.41%0.0123%0.23CC..SBendtrans-142.1164.5177.800000112.7T734 G735T734-G743 WeakPolarHBondContact OG1-CA 3.22Å; G735-G743 WeakPolarHBondContact O-CA 3.19Å
744C97.3Very high92Very high0 Ų046.2 Ų46.20%026%0.256CS..SBendtrans-62.9-46.1-173174.10000113.4P733 T734 C766 I767 Y770 D777P733-C744 HydrophobicContact CB-CB 4.15Å; T734-C744 WeakPolarHBondContact O-CB 3.42Å; T734-C744 PolarHBondContact O-N 3.41Å; T734-C744 VanDerWaalsContact O-N 3.07Å; T734-C744 PolarHBondContact OG1-N 3.14Å; C744-C766 HydrophobicContact CB-CB 3.8Å; C744-C766 WeakPolarHBondContact CB-SG 3.43Å; C744-C766 CarbonylContact O-C 3.54Å; C744-C766 VanDerWaalsContact O-CA 3.23Å; C744-C766 WeakPolarHBondContact O-CA 3.37Å; C744-C766 WeakPolarHBondContact O-CB 3.46Å; C744-C766 WeakPolarHBondContact SG-CA 3.12Å; C744-C766 WeakPolarHBondContact SG-CB 2.99Å; C744-C766 CovalentContact SG-SG 2.03Å; C744-C766 PolarHBondContact SG-SG 3.08Å; C744-I767 PolarHBondContact O-N 3.46Å; C744-Y770 VanDerWaalsContact CA-CD1 3.42Å; C744-Y770 HydrophobicContact CB-CD1 3.64Å; C744-Y770 HydrophobicContact CB-CE1 3.72Å; C744-Y770 HydrophobicContact CB-CG 4.48Å; C744-D777 WeakPolarHBondContact CB-OD2 3.24Å
745K97.2Very high91.1Very high10 Ų1054.1 Ų54.14%0.04329%0.29CS..EExtended strand (participates in β ladder)trans-132.280.7-176-77.1-173.3170.4-174.20111.6S700 E702 D703 C707 P733 T734 G735 T763 I774S700-K745 WeakPolarHBondContact CB-O 3.34Å; S700-K745 WeakPolarHBondContact OG-CB 3.03Å; S700-K745 PolarHBondContact OG-O 3.44Å; E702-K745 HydrophobicContact CB-CB 4.35Å; E702-K745 HydrophobicContact CG-CB 4.48Å; D703-K745 HydrophobicContact CB-CD 3.94Å; D703-K745 IonicContact OD1-NZ 3.98Å; D703-K745 PolarHBondContact OD1-NZ 2.95Å; C707-K745 PolarHBondContact SG-NZ 3.04Å; C707-K745 VanDerWaalsContact SG-NZ 3.44Å; P733-K745 HydrophobicContact CG-CD 4.23Å; T734-K745 PolarHBondContact O-N 3.06Å; G735-K745 WeakPolarHBondContact CA-O 3.44Å; K745-T763 WeakPolarHBondContact CE-O 3.44Å; K745-T763 PolarHBondContact NZ-O 2.94Å; K745-I774 HydrophobicContact CD-CD1 4.29Å
746P97.3Very high90.3Very high19 Ų1959.8 Ų59.812%0.12331%0.314CS..EExtended strand (participates in β ladder)trans-65.5155.3172.531.5-37.6000111.6G736 S740 S748 I767G736-P746 WeakPolarHBondContact O-CA 2.95Å; S740-P746 WeakPolarHBondContact O-CG 3.45Å; P746-S748 PolarHBondContact O-N 3.41Å; P746-I767 HydrophobicContact CG-CD1 4.11Å; P746-I767 HydrophobicContact CG-CG2 3.91Å
747Y97.1Very high89.9Confident13 Ų1360.2 Ų60.25%0.05132%0.317CS..  trans-60.4127.6177.5-162.7-124.1000111.3D667 Q668 S673 V677 D701 L705 G736 Y738 F749D667-Y747 WeakPolarHBondContact O-CE1 3.38Å; Q668-Y747 PolarHBondContact O-OH 3.42Å; S673-Y747 PolarHBondContact OG-OH 3.33Å; V677-Y747 HydrophobicContact CG2-CE2 4.46Å; D701-Y747 WeakPolarHBondContact OD2-CB 3.3Å; D701-Y747 WeakPolarHBondContact OD2-CD2 3.12Å; L705-Y747 HydrophobicContact CD2-CE2 4.2Å; G736-Y747 PolarHBondContact O-N 2.99Å; Y738-Y747 VanDerWaalsContact CA-O 3.26Å; Y738-Y747 WeakPolarHBondContact CA-O 3.16Å; Y747-F749 HydrophobicContact CD1-CB 4.21Å; Y747-F749 HydrophobicContact CE1-CB 3.81Å; Y747-F749 AromaticContact CE1-CD2 3.84Å; Y747-F749 HydrophobicContact CE1-CD2 3.84Å; Y747-F749 HydrophobicContact CE1-CG 4.35Å; Y747-F749 AromaticContact CE2-CD2 3.99Å; Y747-F749 HydrophobicContact CE2-CD2 3.99Å; Y747-F749 HydrophobicContact CE2-CE2 4.5Å; Y747-F749 AromaticContact CZ-CD2 3.55Å
748S94.7Very high89.6Confident48 Ų4867.2 Ų67.234%0.33634%0.339SS..  trans-81-16.3-17260.30000114.3E702 Y738 P746 P760E702-S748 VanDerWaalsContact CD-OG 3.3Å; E702-S748 PolarHBondContact OE1-OG 3.35Å; E702-S748 VanDerWaalsContact OE1-OG 3.08Å; E702-S748 WeakPolarHBondContact OE2-CB 3.38Å; E702-S748 PolarHBondContact OE2-N 3.02Å; E702-S748 PolarHBondContact OE2-OG 3.43Å; Y738-S748 WeakPolarHBondContact CD2-O 3Å; Y738-S748 WeakPolarHBondContact CE2-O 3.47Å; P746-S748 PolarHBondContact O-N 3.41Å; S748-P760 VanDerWaalsContact OG-CG 3.3Å; S748-P760 WeakPolarHBondContact OG-CG 3.43Å
749F94.7Very high89.6Confident25 Ų2563.8 Ų63.811%0.1133%0.331CS..SBendtrans-94.1127.1-177.1-54.5-62.6000113.2C671 L705 Y738 Y747 A757 R758 P760C671-F749 HydrophobicContact CB-CD2 4.05Å; C671-F749 HydrophobicContact CB-CE2 3.93Å; L705-F749 HydrophobicContact CD2-CE2 3.7Å; Y738-F749 VanDerWaalsContact CD2-C 3.47Å; Y747-F749 HydrophobicContact CD1-CB 4.21Å; Y747-F749 HydrophobicContact CE1-CB 3.81Å; Y747-F749 AromaticContact CE1-CD2 3.84Å; Y747-F749 HydrophobicContact CE1-CD2 3.84Å; Y747-F749 HydrophobicContact CE1-CG 4.35Å; Y747-F749 AromaticContact CE2-CD2 3.99Å; Y747-F749 HydrophobicContact CE2-CD2 3.99Å; Y747-F749 HydrophobicContact CE2-CE2 4.5Å; Y747-F749 AromaticContact CZ-CD2 3.55Å; F749-A757 HydrophobicContact CD1-CB 3.89Å; F749-A757 HydrophobicContact CD2-CB 4.39Å; F749-A757 HydrophobicContact CE1-CB 3.59Å; F749-A757 HydrophobicContact CE2-CB 4.1Å; F749-A757 HydrophobicContact CG-CB 4.28Å; F749-A757 HydrophobicContact CZ-CB 3.69Å; F749-R758 VanDerWaalsContact CZ-O 3.29Å; F749-R758 WeakPolarHBondContact CZ-O 3.33Å; F749-P760 HydrophobicContact CE1-CG 4.37Å; F749-P760 HydrophobicContact CE2-CG 4.08Å; F749-P760 HydrophobicContact CZ-CG 3.62Å
750P90.2Very high89.6Confident38 Ų3862.3 Ų62.325%0.24731%0.311CS..PPolyproline II helixtrans-66143.2176.417.4-20.7000111.1S669 Y738 N753S669-P750 WeakPolarHBondContact CB-O 3.28Å; S669-P750 PolarHBondContact OG-O 3.2Å; Y738-P750 HydrophobicContact CD1-CB 4.08Å; Y738-P750 HydrophobicContact CD2-CB 4.25Å; Y738-P750 HydrophobicContact CE1-CB 3.83Å; Y738-P750 HydrophobicContact CE2-CB 4Å; Y738-P750 HydrophobicContact CE2-CG 4.17Å; Y738-P750 HydrophobicContact CG-CB 4.28Å; P750-N753 HydrophobicContact CG-CB 4.02Å; P750-N753 WeakPolarHBondContact O-CB 3.26Å; P750-N753 PolarHBondContact O-N 3.17Å
751P88.3Confident89.5Confident84 Ų8464.9 Ų64.955%0.54533%0.334SS..THydrogen-bonded Turntrans-59.4142.3176.525.9-34.2000110.6D667 N753D667-P751 HydrophobicContact CB-CB 3.99Å; D667-P751 VanDerWaalsContact OD2-CA 3.25Å; D667-P751 WeakPolarHBondContact OD2-CA 3.25Å; D667-P751 VanDerWaalsContact OD2-CB 3.27Å; D667-P751 WeakPolarHBondContact OD2-CB 3.44Å; P751-N753 PolarHBondContact O-N 2.91Å; P751-N753 VanDerWaalsContact O-N 3.17Å
752G78.7Confident89.6Confident19 Ų1962 Ų6220%0.19633%0.329CS..THydrogen-bonded Turntrans66.96.8178.900000117.4D667 R754D667-G752 PolarHBondContact OD2-N 2.91Å; G752-R754 PolarHBondContact O-N 3.42Å
753N79.8Confident89.7Confident54 Ų5460.7 Ų60.729%0.28932%0.321SS..  trans-64.2130.5175.4-171.1-4.4000110.8N670 P750 P751 K755N670-N753 WeakPolarHBondContact CB-O 3.42Å; P750-N753 HydrophobicContact CG-CB 4.02Å; P750-N753 WeakPolarHBondContact O-CB 3.26Å; P750-N753 PolarHBondContact O-N 3.17Å; P751-N753 PolarHBondContact O-N 2.91Å; P751-N753 VanDerWaalsContact O-N 3.17Å; N753-K755 PolarHBondContact OD1-N 2.87Å
754R72Confident89.5Confident143 Ų14366.5 Ų66.554%0.5435%0.352SS..  trans-88.3-17.4179-63-172.6-177.1-166.8-2.7113.5R609 N670 G752 K756R609-R754 VanDerWaalsContact O-CZ 3.26Å; R609-R754 PolarHBondContact O-NH1 3.36Å; R609-R754 PolarHBondContact O-NH2 3.29Å; N670-R754 PolarHBondContact ND2-O 3.48Å; G752-R754 PolarHBondContact O-N 3.42Å; R754-K756 PolarHBondContact O-N 2.86Å
755K77.8Confident89.3Confident167 Ų16774.4 Ų74.473%0.72639%0.386SS*.SBendtrans-66.6130.3179.4-66-174.4-179.9-178.60109.7N753 A757N753-K755 PolarHBondContact OD1-N 2.87Å; K755-A757 PolarHBondContact O-N 3.41Å
756K80.4Confident89.2Confident121 Ų12175.2 Ų75.253%0.52639%0.393SS..PPolyproline II helixtrans-49.6117.3174.6178.8178.8177.1178.80109.5R618 N670 R754R618-K756 VanDerWaalsContact NH1-CE 3.3Å; N670-K756 PolarHBondContact ND2-N 3.05Å; R754-K756 PolarHBondContact O-N 2.86Å
757A86Confident89.2Confident9 Ų976.6 Ų76.67%0.07440%0.398CS..PPolyproline II helixtrans-70.2134.1178.800000110.2N670 C671 F749 K755N670-A757 VanDerWaalsContact O-CB 3.23Å; N670-A757 WeakPolarHBondContact O-CB 3.41Å; N670-A757 PolarHBondContact O-N 2.83Å; N670-A757 VanDerWaalsContact O-N 3.11Å; C671-A757 HydrophobicContact CB-CB 3.56Å; F749-A757 HydrophobicContact CD1-CB 3.89Å; F749-A757 HydrophobicContact CD2-CB 4.39Å; F749-A757 HydrophobicContact CE1-CB 3.59Å; F749-A757 HydrophobicContact CE2-CB 4.1Å; F749-A757 HydrophobicContact CG-CB 4.28Å; F749-A757 HydrophobicContact CZ-CB 3.69Å; K755-A757 PolarHBondContact O-N 3.41Å
758R89.7Confident89Confident219 Ų21986 Ų8683%0.82644%0.439SS*.PPolyproline II helixtrans-97.4135.3168.6-68.2-176.7177.1178.2-1.2107.9F749 P760F749-R758 VanDerWaalsContact CZ-O 3.29Å; F749-R758 WeakPolarHBondContact CZ-O 3.33Å; R758-P760 WeakPolarHBondContact O-CD 3.16Å
759T93Very high89Confident54 Ų5488.6 Ų88.633%0.33145%0.447SS..PPolyproline II helixtrans-50.9123.4175.9-53.70000109.5N713 C715N713-T759 PolarHBondContact O-OG1 3.11Å; C715-T759 PolarHBondContact N-OG1 3.48Å
760P92.8Very high89Confident26 Ų2688.5 Ų88.517%0.16945%0.446CS..PPolyproline II helixtrans-65.3150.5179-21.436.9000110.3E702 L705 S706 S748 F749 R758E702-P760 WeakPolarHBondContact OE1-CB 3.42Å; E702-P760 WeakPolarHBondContact OE1-CG 3.39Å; L705-P760 HydrophobicContact CD2-CG 4.46Å; S706-P760 VanDerWaalsContact CB-O 3.3Å; S706-P760 WeakPolarHBondContact CB-O 3.18Å; S748-P760 VanDerWaalsContact OG-CG 3.3Å; S748-P760 WeakPolarHBondContact OG-CG 3.43Å; F749-P760 HydrophobicContact CE1-CG 4.37Å; F749-P760 HydrophobicContact CE2-CG 4.08Å; F749-P760 HydrophobicContact CZ-CG 3.62Å; R758-P760 WeakPolarHBondContact O-CD 3.16Å
761A92.9Very high89.1Confident83 Ų8392.5 Ų92.569%0.68647%0.472SS*.PPolyproline II helixtrans-67136.5175.300000110.4T763A761-T763 PolarHBondContact O-N 3.48Å
762C95.4Very high89.3Confident65 Ų6591.1 Ų91.144%0.43946%0.462SS..PPolyproline II helixtrans-61.6126.9171.1-179.20000110.5S706 C707S706-C762 VanDerWaalsContact O-CB 3.31Å; S706-C762 WeakPolarHBondContact O-CB 3.27Å; C707-C762 VanDerWaalsContact CA-SG 3.52Å; C707-C762 HydrophobicContact CB-CB 3.95Å; C707-C762 WeakPolarHBondContact CB-SG 3.17Å; C707-C762 WeakPolarHBondContact SG-CA 3.47Å; C707-C762 WeakPolarHBondContact SG-CB 3.37Å; C707-C762 CovalentContact SG-SG 2.04Å; C707-C762 PolarHBondContact SG-SG 3.09Å
763T92.9Very high90Very high76 Ų7695 Ų9547%0.46648%0.478SS..  trans-123.9143.5173.562.10000111K745 A761 K765K745-T763 WeakPolarHBondContact CE-O 3.44Å; K745-T763 PolarHBondContact NZ-O 2.94Å; A761-T763 PolarHBondContact O-N 3.48Å; T763-K765 VanDerWaalsContact C-N 3.27Å; T763-K765 PolarHBondContact O-N 2.71Å
764N90.8Very high90.7Very high123 Ų12393 Ų9366%0.65847%0.467SS*.SBendtrans-9433.8176.2-70.7-28.1000112.2I774N764-I774 WeakPolarHBondContact O-CG2 3.31Å
765K93.1Very high91.6Very high166 Ų16689.8 Ų89.872%0.72247%0.471SS*.SBendtrans-135.1148.5-178.9-64.5-177.1-179.4179.50109.8T763T763-K765 VanDerWaalsContact C-N 3.27Å; T763-K765 PolarHBondContact O-N 2.71Å
766C96.4Very high92.3Very high27 Ų2789.7 Ų89.718%0.18247%0.47CS..  trans-79.4167.1168.4-56.10000110.4C744 Y770 V772C744-C766 HydrophobicContact CB-CB 3.8Å; C744-C766 WeakPolarHBondContact CB-SG 3.43Å; C744-C766 CarbonylContact O-C 3.54Å; C744-C766 VanDerWaalsContact O-CA 3.23Å; C744-C766 WeakPolarHBondContact O-CA 3.37Å; C744-C766 WeakPolarHBondContact O-CB 3.46Å; C744-C766 WeakPolarHBondContact SG-CA 3.12Å; C744-C766 WeakPolarHBondContact SG-CB 2.99Å; C744-C766 CovalentContact SG-SG 2.03Å; C744-C766 PolarHBondContact SG-SG 3.08Å; C766-Y770 HydrophobicContact CB-CD1 4.13Å; C766-V772 PolarHBondContact SG-O 3.26Å
767I95.4Very high93Very high48 Ų4884.4 Ų84.425%0.24645%0.448CS..  trans-55.6150.7164.858166.8000110.4C744 P746 E769 Y770C744-I767 PolarHBondContact O-N 3.46Å; P746-I767 HydrophobicContact CG-CD1 4.11Å; P746-I767 HydrophobicContact CG-CG2 3.91Å; I767-E769 PolarHBondContact O-N 2.95Å; I767-Y770 PolarHBondContact O-N 3.22Å; I767-Y770 VanDerWaalsContact O-N 3.09Å
768K93.1Very high93.4Very high210 Ų21086.8 Ų86.891%0.91346%0.455SS*.THydrogen-bonded Turntrans-60.3-32.5-173.3-69.6-176.9178.7-179.60112.6Y770K768-Y770 VanDerWaalsContact C-N 3.28Å; K768-Y770 PolarHBondContact O-N 3.48Å
769E95Very high93.6Very high104 Ų10478.4 Ų78.449%0.48643%0.425SS..THydrogen-bonded Turntrans-77.2-9.9-178.5-60.299137.600114.1K741 I767K741-E769 HydrophobicContact CB-CB 4.32Å; K741-E769 HydrophobicContact CD-CB 4.2Å; K741-E769 HydrophobicContact CD-CG 4.01Å; K741-E769 WeakPolarHBondContact CE-OE1 3.23Å; K741-E769 HydrophobicContact CG-CB 4.41Å; K741-E769 IonicContact NZ-OE1 2.68Å; K741-E769 PolarHBondContact NZ-OE1 3.2Å; I767-E769 PolarHBondContact O-N 2.95Å
770Y95.7Very high93.6Very high23 Ų2380.8 Ų80.89%0.0943%0.431CS..  trans-96.3118.7179.2-166.3-110.3000111.1K697 T734 T742 C744 C766 I767 K768 V772 D777K697-Y770 PolarHBondContact NZ-OH 3.41Å; T734-Y770 PolarHBondContact OG1-OH 2.74Å; T742-Y770 WeakPolarHBondContact O-CE2 3.22Å; C744-Y770 VanDerWaalsContact CA-CD1 3.42Å; C744-Y770 HydrophobicContact CB-CD1 3.64Å; C744-Y770 HydrophobicContact CB-CE1 3.72Å; C744-Y770 HydrophobicContact CB-CG 4.48Å; C766-Y770 HydrophobicContact CB-CD1 4.13Å; I767-Y770 PolarHBondContact O-N 3.22Å; I767-Y770 VanDerWaalsContact O-N 3.09Å; K768-Y770 VanDerWaalsContact C-N 3.28Å; K768-Y770 PolarHBondContact O-N 3.48Å; Y770-V772 HydrophobicContact CD1-CB 4.18Å; Y770-V772 HydrophobicContact CE1-CB 3.64Å; Y770-V772 HydrophobicContact CE1-CG2 4.15Å; Y770-V772 PolarHBondContact O-N 2.92Å; Y770-D777 HydrophobicContact CE1-CB 4.36Å; Y770-D777 WeakPolarHBondContact CE1-OD1 3.49Å; Y770-D777 PolarHBondContact OH-OD1 3.45Å
771P92Very high93.3Very high122 Ų12280 Ų8079%0.79243%0.426SS*.  trans-79.1-16.6-167.530.2-36000114.4
772V93.2Very high92.8Very high55 Ų5581.5 Ų81.533%0.33342%0.419SS..SBendtrans-89.6131.5-175-173.10000110C766 Y770 K776 D777C766-V772 PolarHBondContact SG-O 3.26Å; Y770-V772 HydrophobicContact CD1-CB 4.18Å; Y770-V772 HydrophobicContact CE1-CB 3.64Å; Y770-V772 HydrophobicContact CE1-CG2 4.15Å; Y770-V772 PolarHBondContact O-N 2.92Å; V772-K776 HydrophobicContact CG1-CB 4Å; V772-D777 HydrophobicContact CG1-CB 4.06Å
773N92.5Very high92.1Very high101 Ų10183.4 Ų83.454%0.5442%0.417SS..  trans-63.5137.7173.9-176.9-75.3000111.1A775 K776 D777N773-A775 PolarHBondContact O-N 3.37Å; N773-A775 WeakPolarHBondContact OD1-CB 3.4Å; N773-A775 PolarHBondContact OD1-N 3.42Å; N773-K776 PolarHBondContact O-N 2.87Å; N773-D777 PolarHBondContact O-N 2.95Å
774I94.3Very high91.4Very high12 Ų1280.4 Ų80.46%0.06240%0.398CS..Hα-helixtrans-50.3-38.3-177.8-167.1171.6000113.6P733 K745 N764 K776 D777 R778P733-I774 HydrophobicContact CB-CG1 3.97Å; P733-I774 HydrophobicContact CG-CD1 4.29Å; P733-I774 HydrophobicContact CG-CG1 4.19Å; K745-I774 HydrophobicContact CD-CD1 4.29Å; N764-I774 WeakPolarHBondContact O-CG2 3.31Å; I774-K776 PolarHBondContact O-N 2.72Å; I774-D777 PolarHBondContact O-N 2.64Å; I774-D777 VanDerWaalsContact O-N 3.15Å; I774-R778 WeakPolarHBondContact O-CG 3.42Å; I774-R778 PolarHBondContact O-N 3.02Å
775A90.8Very high90.7Very high75 Ų7574.8 Ų74.862%0.6237%0.368SS*.Hα-helixtrans-66-29.1-178.700000112.6N773N773-A775 PolarHBondContact O-N 3.37Å; N773-A775 WeakPolarHBondContact OD1-CB 3.4Å; N773-A775 PolarHBondContact OD1-N 3.42Å
776K93.3Very high89.8Confident165 Ų16566.9 Ų66.972%0.71733%0.334SS*.Hα-helixtrans-88.1-13.9176.5-65.9-176.3177.8178.30113.1V772 N773 I774V772-K776 HydrophobicContact CG1-CB 4Å; N773-K776 PolarHBondContact O-N 2.87Å; I774-K776 PolarHBondContact O-N 2.72Å
777D95.2Very high88.2Confident9 Ų966 Ų665%0.04833%0.327CS..Hα-helixtrans-98.8-3.6-176.9-164.668.1000112.8P733 T734 C744 Y770 V772 N773 I774 H779P733-D777 WeakPolarHBondContact CA-O 3.09Å; T734-D777 WeakPolarHBondContact CA-OD2 3.47Å; T734-D777 VanDerWaalsContact CB-OD2 3.28Å; T734-D777 WeakPolarHBondContact CB-OD2 3.4Å; T734-D777 WeakPolarHBondContact CG2-OD1 3.44Å; T734-D777 WeakPolarHBondContact CG2-OD2 3.37Å; T734-D777 PolarHBondContact N-OD2 3.5Å; T734-D777 PolarHBondContact OG1-OD1 3.02Å; T734-D777 PolarHBondContact OG1-OD2 3.04Å; C744-D777 WeakPolarHBondContact CB-OD2 3.24Å; Y770-D777 HydrophobicContact CE1-CB 4.36Å; Y770-D777 WeakPolarHBondContact CE1-OD1 3.49Å; Y770-D777 PolarHBondContact OH-OD1 3.45Å; V772-D777 HydrophobicContact CG1-CB 4.06Å; N773-D777 PolarHBondContact O-N 2.95Å; I774-D777 PolarHBondContact O-N 2.64Å; I774-D777 VanDerWaalsContact O-N 3.15Å; D777-H779 PolarHBondContact O-CD2 2.79Å; D777-H779 PolarHBondContact O-N 2.7Å; D777-H779 PolarHBondContact O-NE2 2.49Å
778R94.3Very high86.5Confident59 Ų5966.9 Ų66.922%0.22333%0.328CS..  trans-74124.1177.7-76.2-174.5-176-77.6-7.4111.7D703 G731 P733 I774D703-R778 IonicContact OD1-NH1 3.11Å; D703-R778 IonicContact OD1-NH2 3.11Å; D703-R778 PolarHBondContact OD1-NH2 3.49Å; D703-R778 IonicContact OD2-CZ 2.66Å; D703-R778 IonicContact OD2-NH1 3.86Å; D703-R778 PolarHBondContact OD2-NH1 3.48Å; D703-R778 IonicContact OD2-NH2 3.99Å; G731-R778 PolarHBondContact O-NH1 2.82Å; P733-R778 HydrophobicContact CB-CG 4.43Å; I774-R778 WeakPolarHBondContact O-CG 3.42Å; I774-R778 PolarHBondContact O-N 3.02Å
779H94.1Very high84.6Confident43 Ų4360.4 Ų60.420%0.19931%0.313CS..BIsolated β-bridgetrans-101.5130.6172.7-60.5-94.4000109.5L699 W727 G731 I732 D777L699-H779 HydrophobicContact CD2-CB 3.91Å; W727-H779 PolarHBondContact NE1-O 2.73Å; G731-H779 CarbonylContact C-O 3.49Å; G731-H779 WeakPolarHBondContact CA-O 3.39Å; I732-H779 PolarHBondContact N-O 2.89Å; I732-H779 PolarHBondContact O-N 3.48Å; D777-H779 PolarHBondContact O-CD2 2.79Å; D777-H779 PolarHBondContact O-N 2.7Å; D777-H779 PolarHBondContact O-NE2 2.49Å
780K92.3Very high83Confident105 Ų10557.1 Ų57.146%0.45731%0.307SS..  trans-108.4148.2-179.6-69.7-169.6179.8-155.10112.2W727 N729 T730W727-K780 WeakPolarHBondContact O-CA 3.42Å; N729-K780 PolarHBondContact O-NZ 3.3Å; T730-K780 VanDerWaalsContact O-CE 3.22Å; T730-K780 WeakPolarHBondContact O-CE 3.43Å
781A87.2Confident81.9Confident8 Ų860 Ų607%0.06632%0.321CS..  trans-79.2149.3165.300000111.7W727 K728 V784 L876W727-A781 HydrophobicContact CD2-CB 3.66Å; W727-A781 HydrophobicContact CE3-CB 3.48Å; W727-A781 VanDerWaalsContact CE3-CB 3.48Å; W727-A781 HydrophobicContact CG-CB 4.2Å; W727-A781 HydrophobicContact CH2-CB 4.32Å; W727-A781 HydrophobicContact CZ2-CB 4.44Å; W727-A781 HydrophobicContact CZ3-CB 3.8Å; W727-A781 PolarHBondContact O-N 3.16Å; K728-A781 HydrophobicContact CB-CB 4.27Å; A781-V784 HydrophobicContact CB-CG2 4.4Å; A781-L876 HydrophobicContact CB-CD2 4.06Å
782Q81.4Confident81.1Confident116 Ų11657.7 Ų57.754%0.54230%0.301SS..SBendtrans-82.7-47.2169.6-173.61802.600110.8K879Q782-K879 HydrophobicContact CB-CB 4.48Å
783R81.4Confident80.1Confident105 Ų10555.7 Ų55.740%0.39629%0.288SS..EExtended strand (participates in β ladder)trans-136.8144.1-175.7-163.5-170.7-172.8170.47.9111.7E635 Y785 L876 D877E635-R783 IonicContact OE1-CZ 3.2Å; E635-R783 IonicContact OE1-NE 3.16Å; E635-R783 PolarHBondContact OE1-NE 3.15Å; E635-R783 VanDerWaalsContact OE1-NE 3.12Å; E635-R783 IonicContact OE1-NH2 3.61Å; E635-R783 PolarHBondContact OE1-NH2 3.37Å; E635-R783 IonicContact OE2-CZ 3.31Å; E635-R783 IonicContact OE2-NE 2.71Å; E635-R783 PolarHBondContact OE2-NE 3.24Å; E635-R783 IonicContact OE2-NH2 2.84Å; E635-R783 PolarHBondContact OE2-NH2 3.07Å; E635-R783 VanDerWaalsContact OE2-NH2 3.08Å; R783-Y785 HydrophobicContact CG-CD1 4.04Å; R783-L876 WeakPolarHBondContact O-CD2 3.04Å; R783-D877 HydrophobicContact CB-CB 4.34Å; R783-D877 PolarHBondContact N-O 3.33Å; R783-D877 PolarHBondContact O-N 2.88Å
784V78.8Confident79.4Confident12 Ų1251.1 Ų51.17%0.07326%0.264CS..EExtended strand (participates in β ladder)trans-131.9133.9177.6175.30000107.6F721 L724 L725 K728 A781 L876F721-V784 HydrophobicContact CD2-CG1 4.48Å; F721-V784 HydrophobicContact CE2-CG1 4.22Å; L724-V784 HydrophobicContact CB-CB 4.4Å; L724-V784 HydrophobicContact CB-CG1 3.41Å; L724-V784 VanDerWaalsContact CB-CG1 3.41Å; L724-V784 HydrophobicContact CB-CG2 4.07Å; L724-V784 HydrophobicContact CD1-CG1 3.98Å; L724-V784 HydrophobicContact CG-CG1 4.35Å; L724-V784 WeakPolarHBondContact O-CG2 3.33Å; L725-V784 HydrophobicContact CD2-CG1 4.33Å; K728-V784 HydrophobicContact CB-CG2 3.7Å; K728-V784 HydrophobicContact CD-CG2 4.11Å; K728-V784 HydrophobicContact CG-CG2 4.4Å; A781-V784 HydrophobicContact CB-CG2 4.4Å; V784-L876 HydrophobicContact CB-CD2 4.24Å; V784-L876 HydrophobicContact CG2-CD2 3.58Å
785Y75.5Confident78.9Confident5 Ų551.3 Ų51.32%0.0226%0.264CS..EExtended strand (participates in β ladder)trans-153161.2-177.151-97.9000112.3E635 V637 R783 Q797 T875 L876 D877E635-Y785 CarbonylContact O-C 3.37Å; E635-Y785 WeakPolarHBondContact O-CA 3.48Å; E635-Y785 WeakPolarHBondContact O-CB 3.44Å; V637-Y785 HydrophobicContact CG2-CD1 4.32Å; V637-Y785 HydrophobicContact CG2-CD2 3.15Å; V637-Y785 HydrophobicContact CG2-CE2 3.54Å; V637-Y785 HydrophobicContact CG2-CG 3.57Å; R783-Y785 HydrophobicContact CG-CD1 4.04Å; Y785-Q797 PolarHBondContact OH-OE1 2.84Å; Y785-T875 WeakPolarHBondContact CE2-OG1 3.38Å; Y785-T875 PolarHBondContact N-O 2.88Å; Y785-T875 CarbonylContact O-C 3.55Å; Y785-T875 PolarHBondContact O-N 2.9Å; Y785-L876 VanDerWaalsContact CE1-C 3.46Å; Y785-L876 PolarHBondContact OH-O 3.29Å; Y785-D877 HydrophobicContact CE1-CB 4.1Å
786G73.7Confident78.5Confident1 Ų148.2 Ų48.21%0.0124%0.237CC..EExtended strand (participates in β ladder)trans-84.1150.9166.800000111M634 E635 I636 V637M634-G786 VanDerWaalsContact SD-CA 3.56Å; E635-G786 PolarHBondContact O-N 3.11Å; I636-G786 WeakPolarHBondContact CA-O 3.5Å; V637-G786 PolarHBondContact N-O 2.89Å; V637-G786 VanDerWaalsContact N-O 3.13Å
787I63.2Low78.2Confident7 Ų740.4 Ų40.44%0.03620%0.203CC..EExtended strand (participates in β ladder)trans-98.2126.5163.3-54.4-175.9000106.9A789 N793 I794 Q797 V804 I873 T875I787-A789 PolarHBondContact O-N 2.87Å; I787-N793 HydrophobicContact CG2-CB 3.69Å; I787-I794 HydrophobicContact CG2-CG1 4.22Å; I787-Q797 HydrophobicContact CD1-CB 3.38Å; I787-Q797 HydrophobicContact CD1-CG 3.39Å; I787-Q797 HydrophobicContact CG1-CB 4.47Å; I787-Q797 HydrophobicContact CG1-CG 3.98Å; I787-Q797 HydrophobicContact CG2-CG 4.48Å; I787-V804 HydrophobicContact CD1-CG1 4.2Å; I787-I873 HydrophobicContact CB-CB 4.23Å; I787-I873 HydrophobicContact CB-CG2 4.02Å; I787-I873 HydrophobicContact CD1-CG2 3.6Å; I787-I873 HydrophobicContact CG1-CG2 4Å; I787-I873 PolarHBondContact N-O 2.99Å; I787-T875 HydrophobicContact CD1-CG2 3.33Å; I787-T875 WeakPolarHBondContact CD1-OG1 3.18Å; I787-T875 HydrophobicContact CG1-CG2 3.88Å; I787-T875 WeakPolarHBondContact CG1-OG1 3.45Å
788R59.8Low77.9Confident68 Ų6840 Ų4026%0.25720%0.201SC..PPolyproline II helixtrans-56.5139.6172.6-165.9177.2170.893.6-2109.3I636 D638 G790 D956I636-R788 HydrophobicContact CG2-CB 3.48Å; I636-R788 VanDerWaalsContact CG2-CB 3.48Å; I636-R788 HydrophobicContact CG2-CG 4.16Å; D638-R788 HydrophobicContact CB-CB 4.48Å; D638-R788 VanDerWaalsContact CG-CD 3.49Å; D638-R788 WeakPolarHBondContact OD2-CD 2.72Å; D638-R788 IonicContact OD2-NE 2.99Å; R788-G790 PolarHBondContact O-N 3.08Å; R788-G790 VanDerWaalsContact O-N 3.14Å; R788-D956 IonicContact NH2-OD2 3.12Å
789A53.5Low77.8Confident74 Ų7438.8 Ų38.861%0.61220%0.199SC*.SBendtrans-57.5121.1176.600000110.1I787I787-A789 PolarHBondContact O-N 2.87Å
790G60.2Low77.5Confident34 Ų3441.8 Ų41.835%0.35121%0.213SC..  trans164.2130.4-179.500000111.5R788 M792 N793 I794R788-G790 PolarHBondContact O-N 3.08Å; R788-G790 VanDerWaalsContact O-N 3.14Å; G790-M792 VanDerWaalsContact C-N 3.3Å; G790-M792 PolarHBondContact O-N 2.86Å; G790-N793 PolarHBondContact O-N 3.35Å; G790-I794 VanDerWaalsContact O-CD1 3.27Å; G790-I794 WeakPolarHBondContact O-CD1 3.19Å; G790-I794 VanDerWaalsContact O-CG1 3.26Å; G790-I794 WeakPolarHBondContact O-CG1 3.33Å; G790-I794 PolarHBondContact O-N 3.05Å
791E72.4Confident77.4Confident85 Ų8539.3 Ų39.340%0.39720%0.201SC..Hα-helixtrans-51.4-48.7-175.6-169.5-168.9143.600111.7N793 I794 M795 K847 W849E791-N793 PolarHBondContact O-N 2.83Å; E791-I794 PolarHBondContact O-N 3.43Å; E791-M795 HydrophobicContact CG-CG 4.42Å; E791-M795 HydrophobicContact CG-SD 3.87Å; E791-M795 VanDerWaalsContact O-CG 3.29Å; E791-M795 WeakPolarHBondContact O-CG 3.36Å; E791-M795 PolarHBondContact O-N 2.9Å; E791-K847 WeakPolarHBondContact OE1-CD 3.44Å; E791-K847 WeakPolarHBondContact OE1-CE 3.09Å; E791-K847 IonicContact OE1-NZ 3.56Å; E791-K847 PolarHBondContact OE1-NZ 2.92Å; E791-K847 IonicContact OE2-NZ 3.91Å; E791-K847 PolarHBondContact OE2-NZ 3Å; E791-W849 HydrophobicContact CG-CH2 4.16Å; E791-W849 HydrophobicContact CG-CZ2 3.92Å
792M76.1Confident77.7Confident72 Ų7239 Ų3936%0.35520%0.198SC..Hα-helixtrans-63.2-43.7-176.7-17157.770.500113.1L645 G790 I794 M795 R796L645-M792 HydrophobicContact CD1-SD 3.58Å; L645-M792 VanDerWaalsContact CD1-SD 3.58Å; L645-M792 HydrophobicContact CG-SD 4.24Å; G790-M792 VanDerWaalsContact C-N 3.3Å; G790-M792 PolarHBondContact O-N 2.86Å; M792-I794 VanDerWaalsContact C-N 3.25Å; M792-I794 PolarHBondContact O-N 2.88Å; M792-M795 PolarHBondContact O-N 3.13Å; M792-R796 WeakPolarHBondContact O-CG 3.47Å; M792-R796 PolarHBondContact O-N 2.96Å
793N73Confident78.4Confident13 Ų1333.4 Ų33.47%0.0717%0.172CC..Hα-helixtrans-61.1-38.1179.2-77.4-27.7000111.3D638 Y639 I787 G790 E791 Q797D638-N793 PolarHBondContact OD1-ND2 3.31Å; Y639-N793 PolarHBondContact N-OD1 3.37Å; I787-N793 HydrophobicContact CG2-CB 3.69Å; G790-N793 PolarHBondContact O-N 3.35Å; E791-N793 PolarHBondContact O-N 2.83Å; N793-Q797 VanDerWaalsContact O-CG 3.22Å; N793-Q797 WeakPolarHBondContact O-CG 3.5Å; N793-Q797 PolarHBondContact O-N 3.35Å
794I76.7Confident78.8Confident6 Ų628.4 Ų28.43%0.03115%0.153CC..Hα-helixtrans-71.7-47.2178.3-55156.5000110.6I787 G790 E791 M792 R796 Q797 I798 V804 W849 I873I787-I794 HydrophobicContact CG2-CG1 4.22Å; G790-I794 VanDerWaalsContact O-CD1 3.27Å; G790-I794 WeakPolarHBondContact O-CD1 3.19Å; G790-I794 VanDerWaalsContact O-CG1 3.26Å; G790-I794 WeakPolarHBondContact O-CG1 3.33Å; G790-I794 PolarHBondContact O-N 3.05Å; E791-I794 PolarHBondContact O-N 3.43Å; M792-I794 VanDerWaalsContact C-N 3.25Å; M792-I794 PolarHBondContact O-N 2.88Å; I794-R796 VanDerWaalsContact C-N 3.29Å; I794-R796 PolarHBondContact O-N 3.38Å; I794-Q797 PolarHBondContact O-N 3.38Å; I794-I798 HydrophobicContact CG2-CD1 3.82Å; I794-I798 HydrophobicContact CG2-CG1 4.44Å; I794-I798 WeakPolarHBondContact O-CG1 3.27Å; I794-I798 PolarHBondContact O-N 3.43Å; I794-V804 HydrophobicContact CG2-CG2 4.14Å; I794-W849 HydrophobicContact CB-CH2 3.58Å; I794-W849 HydrophobicContact CB-CZ2 4.09Å; I794-W849 HydrophobicContact CB-CZ3 4.25Å; I794-W849 HydrophobicContact CD1-CH2 4.2Å; I794-W849 HydrophobicContact CD1-CZ2 3.81Å; I794-W849 HydrophobicContact CG2-CE3 4.4Å; I794-W849 HydrophobicContact CG2-CH2 3.48Å; I794-W849 VanDerWaalsContact CG2-CH2 3.48Å; I794-W849 HydrophobicContact CG2-CZ2 4.04Å; I794-W849 HydrophobicContact CG2-CZ3 3.69Å; I794-I873 HydrophobicContact CB-CD1 4.18Å; I794-I873 HydrophobicContact CD1-CD1 3.13Å; I794-I873 HydrophobicContact CG1-CD1 3.3Å; I794-I873 HydrophobicContact CG2-CD1 3.8Å
795M84.1Confident79.3Confident15 Ų1527.9 Ų27.97%0.07415%0.15CC..Hα-helixtrans-57.4-43.2177.5-68.1168.780.100110.8L645 E791 M792 Q797 I798 N799 W840 W849L645-M795 HydrophobicContact CB-CE 4.36Å; L645-M795 HydrophobicContact CD1-CB 3.45Å; L645-M795 VanDerWaalsContact CD1-CB 3.45Å; L645-M795 HydrophobicContact CD1-CE 4.49Å; E791-M795 HydrophobicContact CG-CG 4.42Å; E791-M795 HydrophobicContact CG-SD 3.87Å; E791-M795 VanDerWaalsContact O-CG 3.29Å; E791-M795 WeakPolarHBondContact O-CG 3.36Å; E791-M795 PolarHBondContact O-N 2.9Å; M792-M795 PolarHBondContact O-N 3.13Å; M795-Q797 PolarHBondContact O-N 3.29Å; M795-I798 PolarHBondContact O-N 3.45Å; M795-N799 VanDerWaalsContact O-CB 3.26Å; M795-N799 WeakPolarHBondContact O-CB 3.08Å; M795-N799 PolarHBondContact O-N 3Å; M795-W840 HydrophobicContact CB-CD2 4.41Å; M795-W840 HydrophobicContact CB-CE3 4.29Å; M795-W840 HydrophobicContact CB-CH2 4.03Å; M795-W840 HydrophobicContact CB-CZ2 4.17Å; M795-W840 HydrophobicContact CB-CZ3 4.13Å; M795-W840 HydrophobicContact CE-CD2 4.13Å; M795-W840 VanDerWaalsContact CE-CE2 3.46Å; M795-W840 HydrophobicContact CE-CG 4.24Å; M795-W840 HydrophobicContact CE-CZ2 3.84Å; M795-W840 HydrophobicContact CG-CD2 3.98Å; M795-W840 HydrophobicContact CG-CE3 4.2Å; M795-W840 HydrophobicContact CG-CG 4.35Å; M795-W840 HydrophobicContact CG-CZ2 4.43Å; M795-W840 VanDerWaalsContact O-CH2 3.31Å; M795-W840 WeakPolarHBondContact O-CH2 3.23Å; M795-W840 VanDerWaalsContact O-CZ3 3.28Å; M795-W840 WeakPolarHBondContact O-CZ3 3.06Å; M795-W849 HydrophobicContact CG-CH2 3.68Å; M795-W849 HydrophobicContact CG-CZ3 3.9Å
796R82.9Confident79.7Confident11 Ų1127.7 Ų27.74%0.04215%0.149CC..Hα-helixtrans-59.2-47.9175.7-75.4-173.9-177.2139.420.6112.3Y639 L641 E643 L645 M792 I794 I798 N799 Q800Y639-R796 PolarHBondContact O-NH1 3.46Å; L641-R796 PolarHBondContact O-NH1 3.36Å; L641-R796 PolarHBondContact O-NH2 2.64Å; E643-R796 IonicContact OE2-NE 3.2Å; L645-R796 HydrophobicContact CD1-CG 3.75Å; L645-R796 HydrophobicContact CD2-CG 4.45Å; M792-R796 WeakPolarHBondContact O-CG 3.47Å; M792-R796 PolarHBondContact O-N 2.96Å; I794-R796 VanDerWaalsContact C-N 3.29Å; I794-R796 PolarHBondContact O-N 3.38Å; R796-I798 VanDerWaalsContact C-N 3.31Å; R796-I798 PolarHBondContact O-N 3.09Å; R796-N799 WeakPolarHBondContact O-CB 3.45Å; R796-N799 PolarHBondContact O-N 2.92Å; R796-N799 VanDerWaalsContact O-N 3.13Å; R796-Q800 WeakPolarHBondContact O-CB 3.17Å; R796-Q800 PolarHBondContact O-N 3.21Å
797Q85.4Confident80Confident1 Ų128.2 Ų28.21%0.00515%0.152CC..Hα-helixtrans-65.2-38.2-178.1-72.2-67.4-45.900111.9Y639 R686 Y785 I787 N793 I794 M795 Y801 G802 V804Y639-Q797 PolarHBondContact OH-NE2 3.05Å; Y639-Q797 VanDerWaalsContact OH-NE2 3.07Å; R686-Q797 PolarHBondContact NH2-O 3.49Å; Y785-Q797 PolarHBondContact OH-OE1 2.84Å; I787-Q797 HydrophobicContact CD1-CB 3.38Å; I787-Q797 HydrophobicContact CD1-CG 3.39Å; I787-Q797 HydrophobicContact CG1-CB 4.47Å; I787-Q797 HydrophobicContact CG1-CG 3.98Å; I787-Q797 HydrophobicContact CG2-CG 4.48Å; N793-Q797 VanDerWaalsContact O-CG 3.22Å; N793-Q797 WeakPolarHBondContact O-CG 3.5Å; N793-Q797 PolarHBondContact O-N 3.35Å; I794-Q797 PolarHBondContact O-N 3.38Å; M795-Q797 PolarHBondContact O-N 3.29Å; Q797-Y801 PolarHBondContact O-N 3.24Å; Q797-G802 PolarHBondContact O-N 2.88Å; Q797-V804 HydrophobicContact CB-CG1 4.29Å
798I89.7Confident80.5Confident0 Ų028.5 Ų28.50%015%0.153CC..Hα-helixtrans-67.6-42.6171.9-62.6165.5000110.7L649 W655 I794 M795 R796 G802 V804 I837 W840 W849L649-I798 HydrophobicContact CD2-CG2 3.68Å; W655-I798 VanDerWaalsContact CH2-O 3.25Å; W655-I798 WeakPolarHBondContact CH2-O 3.15Å; I794-I798 HydrophobicContact CG2-CD1 3.82Å; I794-I798 HydrophobicContact CG2-CG1 4.44Å; I794-I798 WeakPolarHBondContact O-CG1 3.27Å; I794-I798 PolarHBondContact O-N 3.43Å; M795-I798 PolarHBondContact O-N 3.45Å; R796-I798 VanDerWaalsContact C-N 3.31Å; R796-I798 PolarHBondContact O-N 3.09Å; I798-G802 WeakPolarHBondContact CA-O 3.46Å; I798-G802 WeakPolarHBondContact O-CA 3.29Å; I798-G802 PolarHBondContact O-N 2.83Å; I798-V804 HydrophobicContact CD1-CG2 3.89Å; I798-V804 HydrophobicContact CG1-CB 4.33Å; I798-V804 HydrophobicContact CG1-CG1 3.62Å; I798-V804 HydrophobicContact CG1-CG2 3.76Å; I798-I837 HydrophobicContact CD1-CB 4.2Å; I798-I837 HydrophobicContact CD1-CG2 3.57Å; I798-W840 HydrophobicContact CB-CE3 4.22Å; I798-W840 HydrophobicContact CB-CZ3 3.71Å; I798-W840 HydrophobicContact CD1-CE3 4.29Å; I798-W840 HydrophobicContact CG2-CE3 4.06Å; I798-W840 HydrophobicContact CG2-CZ3 3.67Å; I798-W849 HydrophobicContact CD1-CE3 4.16Å; I798-W849 HydrophobicContact CD1-CZ3 3.86Å
799N91.5Very high81.2Confident34 Ų3426.6 Ų26.618%0.18215%0.151CC..Hα-helixtrans-60.6-47.9179.6-168.445.6000111.9L645 L649 K654 W655 M795 R796 W840L645-N799 HydrophobicContact CD2-CB 4.01Å; L645-N799 WeakPolarHBondContact CD2-ND2 3.28Å; L649-N799 HydrophobicContact CD1-CB 4.21Å; L649-N799 VanDerWaalsContact CD1-OD1 3.26Å; L649-N799 WeakPolarHBondContact CD1-OD1 3.44Å; K654-N799 PolarHBondContact NZ-O 2.92Å; K654-N799 PolarHBondContact NZ-OD1 3.23Å; W655-N799 WeakPolarHBondContact CH2-O 3.31Å; W655-N799 WeakPolarHBondContact CZ2-O 3.36Å; M795-N799 VanDerWaalsContact O-CB 3.26Å; M795-N799 WeakPolarHBondContact O-CB 3.08Å; M795-N799 PolarHBondContact O-N 3Å; R796-N799 WeakPolarHBondContact O-CB 3.45Å; R796-N799 PolarHBondContact O-N 2.92Å; R796-N799 VanDerWaalsContact O-N 3.13Å; N799-W840 HydrophobicContact CB-CH2 3.98Å
800Q88.6Confident82.5Confident106 Ų10623.1 Ų23.150%0.49512%0.122SC..Hα-helixtrans-84.7-41.9-170.1-169.1173.215.800112.1R796R796-Q800 WeakPolarHBondContact O-CB 3.17Å; R796-Q800 PolarHBondContact O-N 3.21Å
801Y90.2Very high83.4Confident53 Ų5325.3 Ų25.321%0.20812%0.121CC..Hα-helixtrans-118.2-7.2-169-54.5-72.6000113.8R686 Q797R686-Y801 WeakPolarHBondContact CG-O 3.26Å; Q797-Y801 PolarHBondContact O-N 3.24Å
802G93.7Very high83.8Confident0 Ų021.5 Ų21.50%010%0.104CC..  trans88.2-163.3-178.900000114.2R686 Q797 I798R686-G802 PolarHBondContact NH2-O 3.36Å; Q797-G802 PolarHBondContact O-N 2.88Å; I798-G802 WeakPolarHBondContact CA-O 3.46Å; I798-G802 WeakPolarHBondContact O-CA 3.29Å; I798-G802 PolarHBondContact O-N 2.83Å
803P95.5Very high84.1Confident0 Ų018.1 Ų18.10%09%0.087CC..  trans-49152.1-167.1-3237.8000116.3A651 I662 V682 D685 R686 R836 I837 I838A651-P803 HydrophobicContact CB-CG 4.05Å; I662-P803 HydrophobicContact CG2-CG 4.49Å; V682-P803 WeakPolarHBondContact CG1-O 3.28Å; V682-P803 HydrophobicContact CG2-CB 4.48Å; D685-P803 HydrophobicContact CB-CB 4.36Å; D685-P803 HydrophobicContact CB-CG 3.97Å; R686-P803 PolarHBondContact NE-O 2.99Å; R686-P803 PolarHBondContact NH2-O 2.94Å; P803-R836 HydrophobicContact CB-CG 4Å; P803-I837 CarbonylContact C-O 3.49Å; P803-I837 WeakPolarHBondContact CA-O 3.48Å; P803-I837 VanDerWaalsContact CB-O 3.32Å; P803-I837 WeakPolarHBondContact CB-O 3.15Å; P803-I838 HydrophobicContact CB-CG2 4.12Å; P803-I838 HydrophobicContact CG-CB 4.35Å; P803-I838 HydrophobicContact CG-CG2 3.98Å
804V91.2Very high84.9Confident0 Ų017.5 Ų17.50%08%0.083CC..EExtended strand (participates in β ladder)trans-129.4156.7-175.1-57.20000112.3R686 I787 I794 Q797 I798 R836 I837 I873 T875R686-V804 VanDerWaalsContact NH2-CG1 3.29Å; I787-V804 HydrophobicContact CD1-CG1 4.2Å; I794-V804 HydrophobicContact CG2-CG2 4.14Å; Q797-V804 HydrophobicContact CB-CG1 4.29Å; I798-V804 HydrophobicContact CD1-CG2 3.89Å; I798-V804 HydrophobicContact CG1-CB 4.33Å; I798-V804 HydrophobicContact CG1-CG1 3.62Å; I798-V804 HydrophobicContact CG1-CG2 3.76Å; V804-R836 CarbonylContact O-C 2.92Å; V804-R836 WeakPolarHBondContact O-CA 3.47Å; V804-I837 HydrophobicContact CG2-CB 3.71Å; V804-I837 HydrophobicContact CG2-CD1 4.19Å; V804-I837 HydrophobicContact CG2-CG1 4.17Å; V804-I837 PolarHBondContact N-O 3.11Å; V804-I837 PolarHBondContact O-N 3.16Å; V804-I873 HydrophobicContact CB-CG2 4.15Å; V804-I873 HydrophobicContact CG2-CG2 4.14Å; V804-T875 HydrophobicContact CB-CG2 3.31Å; V804-T875 HydrophobicContact CG1-CG2 3.31Å
805I89Confident85.6Confident1 Ų117.2 Ų17.21%0.0058%0.082CC..EExtended strand (participates in β ladder)trans-93.6125.8175.1-47.6163.9000108.6A679 V682 P720 L724 A834 V835 I873 C874A679-I805 HydrophobicContact CB-CD1 3.82Å; V682-I805 HydrophobicContact CB-CD1 4.39Å; V682-I805 HydrophobicContact CB-CG1 3.75Å; V682-I805 HydrophobicContact CG1-CG1 4.07Å; V682-I805 HydrophobicContact CG2-CG1 3.56Å; P720-I805 HydrophobicContact CB-CD1 4.42Å; P720-I805 HydrophobicContact CB-CG2 3.97Å; P720-I805 HydrophobicContact CG-CG2 4.33Å; L724-I805 HydrophobicContact CD1-CD1 4.17Å; L724-I805 HydrophobicContact CD2-CD1 3.68Å; L724-I805 HydrophobicContact CG-CD1 4.1Å; I805-A834 HydrophobicContact CG2-CB 4.49Å; I805-V835 WeakPolarHBondContact CA-O 3.47Å; I805-I873 WeakPolarHBondContact O-CA 3.46Å; I805-I873 WeakPolarHBondContact O-CG2 3.35Å; I805-C874 PolarHBondContact O-N 2.97Å
806A84Confident86Confident0 Ų016.5 Ų16.50%08%0.078CC..EExtended strand (participates in β ladder)trans-119.7140174.800000111.1A834 V835 I837 L869 I873A806-A834 CarbonylContact O-C 3.56Å; A806-A834 WeakPolarHBondContact O-CA 3.31Å; A806-V835 HydrophobicContact CB-CG2 4.21Å; A806-V835 PolarHBondContact N-O 2.84Å; A806-V835 PolarHBondContact O-N 2.76Å; A806-I837 HydrophobicContact CB-CD1 3.54Å; A806-I837 HydrophobicContact CB-CG1 3.81Å; A806-L869 HydrophobicContact CB-CD1 4.49Å; A806-I873 HydrophobicContact CB-CD1 4.35Å; A806-I873 HydrophobicContact CB-CG1 3.85Å
807I80Confident86.4Confident13 Ų1316 Ų167%0.0678%0.076CC..EExtended strand (participates in β ladder)trans-107.8128.9171.4-59.3167.8000108.1V622 F624 P720 N832 H833 A834 S871 L872V622-I807 HydrophobicContact CB-CG2 4.45Å; V622-I807 HydrophobicContact CG1-CD1 4.08Å; V622-I807 HydrophobicContact CG1-CG1 4.43Å; V622-I807 HydrophobicContact CG1-CG2 3.89Å; V622-I807 HydrophobicContact CG2-CG2 4.35Å; F624-I807 HydrophobicContact CE1-CD1 4.43Å; F624-I807 HydrophobicContact CZ-CG2 4.04Å; P720-I807 HydrophobicContact CG-CD1 3.92Å; P720-I807 HydrophobicContact CG-CG1 4.09Å; I807-N832 HydrophobicContact CG2-CB 4.21Å; I807-H833 WeakPolarHBondContact CA-O 3.21Å; I807-A834 HydrophobicContact CG1-CB 4.36Å; I807-S871 WeakPolarHBondContact O-CB 3.09Å; I807-L872 PolarHBondContact N-O 2.82Å
808F73.9Confident86.7Confident13 Ų1319.3 Ų19.36%0.0579%0.091CC..EExtended strand (participates in β ladder)trans-137.4157.3177.274.6-71.1000111.7V810 F814 N832 H833 V835 L869F808-V810 HydrophobicContact CD2-CG2 4.29Å; F808-V810 HydrophobicContact CE1-CG2 4.33Å; F808-V810 HydrophobicContact CE2-CG2 3.6Å; F808-V810 HydrophobicContact CZ-CG2 3.62Å; F808-F814 HydrophobicContact CE2-CE1 4.24Å; F808-F814 HydrophobicContact CE2-CE2 4.25Å; F808-F814 HydrophobicContact CE2-CZ 4.04Å; F808-F814 AromaticContact CZ-CE1 3.79Å; F808-F814 HydrophobicContact CZ-CE1 3.79Å; F808-F814 HydrophobicContact CZ-CE2 4.28Å; F808-F814 AromaticContact CZ-CZ 3.64Å; F808-F814 HydrophobicContact CZ-CZ 3.64Å; F808-N832 WeakPolarHBondContact O-CA 3.21Å; F808-H833 HydrophobicContact CD1-CB 4.48Å; F808-H833 WeakPolarHBondContact CD1-O 3.39Å; F808-H833 HydrophobicContact CE1-CB 3.93Å; F808-H833 AromaticContact CE1-CD2 3.85Å; F808-H833 HydrophobicContact CZ-CB 4.31Å; F808-H833 PolarHBondContact N-O 3.47Å; F808-H833 PolarHBondContact O-N 2.89Å; F808-V835 HydrophobicContact CD1-CG1 4.46Å; F808-V835 HydrophobicContact CD1-CG2 3.84Å; F808-V835 HydrophobicContact CE1-CB 4.33Å; F808-V835 HydrophobicContact CE1-CG1 3.61Å; F808-V835 HydrophobicContact CE1-CG2 3.78Å; F808-V835 HydrophobicContact CZ-CG1 4.44Å; F808-L869 HydrophobicContact CB-CD2 3.79Å; F808-L869 HydrophobicContact CD1-CD2 4.16Å; F808-L869 HydrophobicContact CD2-CD2 3.69Å; F808-L869 HydrophobicContact CE2-CD2 4.32Å; F808-L869 HydrophobicContact CG-CD2 3.61Å
809A74.1Confident86.7Confident28 Ų2820.5 Ų20.523%0.23110%0.1CC..EExtended strand (participates in β ladder)trans-74.6127.117300000110Y811 K829A809-Y811 HydrophobicContact CB-CE2 4.16Å; A809-K829 HydrophobicContact CB-CD 3.93Å; A809-K829 HydrophobicContact CB-CG 4.19Å
810V80.3Confident86.6Confident0 Ų019.8 Ų19.80%010%0.1CC..EExtended strand (participates in β ladder)trans-94.7128.8175.1171.30000109.6L620 F808 F814 I830 G831 H833L620-V810 HydrophobicContact CD1-CB 4.01Å; L620-V810 HydrophobicContact CD1-CG1 4.07Å; L620-V810 HydrophobicContact CD2-CB 4.03Å; L620-V810 HydrophobicContact CD2-CG1 4.03Å; L620-V810 HydrophobicContact CD2-CG2 3.89Å; F808-V810 HydrophobicContact CD2-CG2 4.29Å; F808-V810 HydrophobicContact CE1-CG2 4.33Å; F808-V810 HydrophobicContact CE2-CG2 3.6Å; F808-V810 HydrophobicContact CZ-CG2 3.62Å; V810-F814 HydrophobicContact CG1-CB 4.05Å; V810-F814 HydrophobicContact CG1-CD1 3.75Å; V810-F814 HydrophobicContact CG1-CG 4.26Å; V810-F814 HydrophobicContact CG2-CD1 4.14Å; V810-F814 HydrophobicContact CG2-CE1 4.35Å; V810-I830 PolarHBondContact O-N 3.18Å; V810-G831 PolarHBondContact N-O 3.44Å; V810-H833 HydrophobicContact CG2-CB 3.44Å; V810-H833 VanDerWaalsContact CG2-CB 3.44Å
811Y78.7Confident86.4Confident80 Ų8014.9 Ų14.931%0.3148%0.077SC..EExtended strand (participates in β ladder)trans-102.3159.5174.3-63.8-96.2000110.9A809 D813 F814 H824 G828 K829A809-Y811 HydrophobicContact CB-CE2 4.16Å; Y811-D813 VanDerWaalsContact C-N 3.29Å; Y811-D813 PolarHBondContact O-N 3.01Å; Y811-F814 WeakPolarHBondContact O-CB 3.43Å; Y811-F814 PolarHBondContact O-N 3.24Å; Y811-F814 VanDerWaalsContact O-N 3.07Å; Y811-H824 VanDerWaalsContact CB-ND1 3.31Å; Y811-H824 WeakPolarHBondContact CB-ND1 3.43Å; Y811-H824 AromaticContact CD1-CD2 3.92Å; Y811-H824 AromaticContact CD1-CE1 3.44Å; Y811-H824 VanDerWaalsContact CD1-CE1 3.44Å; Y811-H824 WeakPolarHBondContact CD1-CE1 3.37Å; Y811-H824 AromaticContact CD1-ND1 3.82Å; Y811-H824 AromaticContact CD1-NE2 3.53Å; Y811-H824 HydrophobicContact CD2-CB 4.24Å; Y811-H824 AromaticContact CD2-CG 3.95Å; Y811-H824 AromaticContact CE1-NE2 3.89Å; Y811-H824 HydrophobicContact CG-CB 4.49Å; Y811-H824 AromaticContact CG-CE1 3.59Å; Y811-H824 AromaticContact CG-CG 3.76Å; Y811-H824 AromaticContact CG-ND1 3.47Å; Y811-H824 AromaticContact CG-NE2 4Å; Y811-G828 VanDerWaalsContact CA-O 3.29Å; Y811-G828 WeakPolarHBondContact CA-O 3.48Å; Y811-K829 HydrophobicContact CD1-CB 4.29Å; Y811-K829 HydrophobicContact CE1-CB 4.08Å
812S82Confident86.1Confident6 Ų613 Ų134%0.0427%0.07CC..G310 helixtrans-62.8-29.4-173.478.20000114.9H581 F814 Y815 Y816 G827 G828 I830H581-S812 WeakPolarHBondContact NE2-CB 2.96Å; H581-S812 PolarHBondContact NE2-OG 3.39Å; S812-F814 PolarHBondContact O-N 3Å; S812-Y815 WeakPolarHBondContact O-CD2 3.44Å; S812-Y816 WeakPolarHBondContact O-CE2 3.43Å; S812-G827 VanDerWaalsContact OG-CA 3.25Å; S812-G827 WeakPolarHBondContact OG-CA 3.45Å; S812-G828 PolarHBondContact N-O 2.99Å; S812-G828 VanDerWaalsContact N-O 3.09Å; S812-I830 VanDerWaalsContact CB-CD1 3.49Å
813D82.2Confident85.3Confident0 Ų014.9 Ų14.90%08%0.081CC..G310 helixtrans-67.6-20.3175.561.9-0.8000113.9L585 W600 Y811 Y815 Y816 Y822 H824 K825 K826L585-D813 HydrophobicContact CD1-CB 4.41Å; W600-D813 HydrophobicContact CH2-CB 4.33Å; Y811-D813 VanDerWaalsContact C-N 3.29Å; Y811-D813 PolarHBondContact O-N 3.01Å; D813-Y815 VanDerWaalsContact C-N 3.28Å; D813-Y815 PolarHBondContact O-N 3.23Å; D813-Y816 PolarHBondContact O-N 3.05Å; D813-Y816 VanDerWaalsContact O-N 3.09Å; D813-Y822 PolarHBondContact OD1-OH 2.87Å; D813-H824 IonicContact OD1-CE1 3.91Å; D813-H824 IonicContact OD1-ND1 2.64Å; D813-H824 PolarHBondContact OD1-ND1 3.15Å; D813-H824 VanDerWaalsContact OD1-ND1 3.11Å; D813-H824 IonicContact OD2-CE1 3.23Å; D813-H824 IonicContact OD2-CG 2.66Å; D813-H824 IonicContact OD2-ND1 3.64Å; D813-H824 PolarHBondContact OD2-ND1 3.48Å; D813-H824 VanDerWaalsContact OD2-ND1 3.11Å; D813-K825 PolarHBondContact OD2-N 3.42Å; D813-K826 WeakPolarHBondContact CB-O 3.45Å; D813-K826 PolarHBondContact OD2-N 3.42Å
814F89.1Confident84.3Confident0 Ų017.4 Ų17.40%09%0.093CC..G310 helixtrans-63.5-30-177.3-173.6-114.6000113.5F808 V810 Y811 S812 Y816 Y817 Y822 W855 W859 L865F808-F814 HydrophobicContact CE2-CE1 4.24Å; F808-F814 HydrophobicContact CE2-CE2 4.25Å; F808-F814 HydrophobicContact CE2-CZ 4.04Å; F808-F814 AromaticContact CZ-CE1 3.79Å; F808-F814 HydrophobicContact CZ-CE1 3.79Å; F808-F814 HydrophobicContact CZ-CE2 4.28Å; F808-F814 AromaticContact CZ-CZ 3.64Å; F808-F814 HydrophobicContact CZ-CZ 3.64Å; V810-F814 HydrophobicContact CG1-CB 4.05Å; V810-F814 HydrophobicContact CG1-CD1 3.75Å; V810-F814 HydrophobicContact CG1-CG 4.26Å; V810-F814 HydrophobicContact CG2-CD1 4.14Å; V810-F814 HydrophobicContact CG2-CE1 4.35Å; Y811-F814 WeakPolarHBondContact O-CB 3.43Å; Y811-F814 PolarHBondContact O-N 3.24Å; Y811-F814 VanDerWaalsContact O-N 3.07Å; S812-F814 PolarHBondContact O-N 3Å; F814-Y816 PolarHBondContact O-N 3.08Å; F814-Y816 VanDerWaalsContact O-N 3.13Å; F814-Y817 WeakPolarHBondContact O-CB 3.38Å; F814-Y817 PolarHBondContact O-N 2.89Å; F814-Y822 HydrophobicContact CB-CE2 4.3Å; F814-Y822 AromaticContact CD2-CD1 3.93Å; F814-Y822 HydrophobicContact CD2-CD1 3.93Å; F814-Y822 HydrophobicContact CD2-CD2 4.15Å; F814-Y822 AromaticContact CD2-CE1 3.68Å; F814-Y822 HydrophobicContact CD2-CE1 3.68Å; F814-Y822 AromaticContact CD2-CE2 3.91Å; F814-Y822 HydrophobicContact CD2-CE2 3.91Å; F814-Y822 HydrophobicContact CD2-CG 4.16Å; F814-Y822 AromaticContact CD2-CZ 3.68Å; F814-Y822 HydrophobicContact CE2-CD1 4.21Å; F814-Y822 HydrophobicContact CE2-CE1 4.33Å; F814-Y822 HydrophobicContact CE2-CG 4.47Å; F814-W855 AromaticContact CD1-CH2 3.59Å; F814-W855 HydrophobicContact CD1-CH2 3.59Å; F814-W855 AromaticContact CD1-CZ3 3.75Å; F814-W855 HydrophobicContact CD1-CZ3 3.75Å; F814-W855 AromaticContact CE1-CH2 3.54Å; F814-W855 HydrophobicContact CE1-CH2 3.54Å; F814-W855 HydrophobicContact CE1-CZ2 4.46Å; F814-W855 AromaticContact CE1-CZ3 3.54Å; F814-W855 HydrophobicContact CE1-CZ3 3.54Å; F814-W859 HydrophobicContact CD1-CZ2 4.2Å; F814-W859 HydrophobicContact CD2-CZ2 4.28Å; F814-W859 AromaticContact CE1-CH2 3.95Å; F814-W859 HydrophobicContact CE1-CH2 3.95Å; F814-W859 AromaticContact CE1-CZ2 3.7Å; F814-W859 HydrophobicContact CE1-CZ2 3.7Å; F814-W859 AromaticContact CE2-CH2 3.81Å; F814-W859 HydrophobicContact CE2-CH2 3.81Å; F814-W859 AromaticContact CE2-CZ2 3.79Å; F814-W859 HydrophobicContact CE2-CZ2 3.79Å; F814-W859 HydrophobicContact CG-CZ2 4.48Å; F814-W859 AromaticContact CZ-CH2 3.36Å; F814-W859 HydrophobicContact CZ-CH2 3.36Å; F814-W859 AromaticContact CZ-CZ2 3.47Å; F814-W859 HydrophobicContact CZ-CZ2 3.47Å; F814-W859 VanDerWaalsContact CZ-CZ2 3.47Å; F814-W859 PolarHBondContact O-NE1 3.43Å; F814-L865 HydrophobicContact CE2-CD1 3.84Å; F814-L865 HydrophobicContact CE2-CD2 3.58Å; F814-L865 HydrophobicContact CE2-CG 4.32Å; F814-L865 HydrophobicContact CZ-CD2 3.77Å
815Y91.4Very high83.3Confident0 Ų023 Ų230%012%0.117CC..G310 helixtrans-63.9-18.5176.7-59.8-58.7000113.3Y578 N605 F608 M616 S812 D813 I830 W855Y578-Y815 PolarHBondContact OH-O 2.77Å; N605-Y815 PolarHBondContact ND2-O 3.22Å; F608-Y815 HydrophobicContact CD2-CD1 4.33Å; F608-Y815 WeakPolarHBondContact CD2-O 3.22Å; F608-Y815 HydrophobicContact CE1-CD1 4.1Å; F608-Y815 HydrophobicContact CE1-CE1 4.5Å; F608-Y815 AromaticContact CE2-CD1 3.73Å; F608-Y815 HydrophobicContact CE2-CD1 3.73Å; F608-Y815 HydrophobicContact CE2-CG 4.27Å; F608-Y815 AromaticContact CZ-CD1 3.61Å; F608-Y815 HydrophobicContact CZ-CD1 3.61Å; F608-Y815 HydrophobicContact CZ-CE1 4.29Å; M616-Y815 HydrophobicContact CB-CE1 3.97Å; M616-Y815 HydrophobicContact CB-CE2 4.14Å; M616-Y815 HydrophobicContact CE-CD2 4.39Å; M616-Y815 HydrophobicContact CE-CE2 4.4Å; M616-Y815 HydrophobicContact SD-CD1 4.27Å; M616-Y815 HydrophobicContact SD-CD2 3.97Å; M616-Y815 HydrophobicContact SD-CE2 4.19Å; M616-Y815 HydrophobicContact SD-CG 4Å; S812-Y815 WeakPolarHBondContact O-CD2 3.44Å; D813-Y815 VanDerWaalsContact C-N 3.28Å; D813-Y815 PolarHBondContact O-N 3.23Å; Y815-I830 HydrophobicContact CD2-CD1 4.28Å; Y815-I830 HydrophobicContact CE2-CD1 3.39Å; Y815-W855 AromaticContact CD1-CH2 3.76Å; Y815-W855 HydrophobicContact CD1-CH2 3.76Å; Y815-W855 HydrophobicContact CD1-CZ3 4.08Å; Y815-W855 AromaticContact CE1-CH2 3.73Å; Y815-W855 HydrophobicContact CE1-CH2 3.73Å; Y815-W855 HydrophobicContact CE1-CZ2 4.23Å; Y815-W855 HydrophobicContact CE1-CZ3 4.49Å
816Y92.6Very high82.4Confident0 Ų027.1 Ų27.10%014%0.135CC..G310 helixtrans-104.46.9-176.9-51.8-75.3000113.4Y578 H581 Y582 L585 F602 G603 L604 S812 D813 F814 K818Y578-Y816 HydrophobicContact CD2-CD1 4.43Å; Y578-Y816 AromaticContact CD2-CE1 3.53Å; Y578-Y816 HydrophobicContact CD2-CE1 3.53Å; Y578-Y816 AromaticContact CD2-CZ 3.78Å; Y578-Y816 HydrophobicContact CE1-CE1 4.34Å; Y578-Y816 AromaticContact CE2-CD1 3.54Å; Y578-Y816 HydrophobicContact CE2-CD1 3.54Å; Y578-Y816 AromaticContact CE2-CE1 3.05Å; Y578-Y816 HydrophobicContact CE2-CE1 3.05Å; Y578-Y816 HydrophobicContact CE2-CG 4.44Å; Y578-Y816 AromaticContact CE2-CZ 3.64Å; Y578-Y816 HydrophobicContact CG-CE1 4.33Å; Y578-Y816 AromaticContact CZ-CD1 3.71Å; Y578-Y816 AromaticContact CZ-CE1 3.52Å; Y578-Y816 WeakPolarHBondContact O-CE1 3.33Å; Y578-Y816 PolarHBondContact O-OH 3.06Å; H581-Y816 WeakPolarHBondContact CB-OH 3.45Å; H581-Y816 AromaticContact CD2-CE2 3.69Å; H581-Y816 AromaticContact CD2-CZ 3.96Å; H581-Y816 PolarHBondContact CD2-OH 3.01Å; Y582-Y816 AromaticContact CD2-CD1 3.64Å; Y582-Y816 HydrophobicContact CD2-CD1 3.64Å; Y582-Y816 AromaticContact CD2-CE1 3.98Å; Y582-Y816 HydrophobicContact CD2-CE1 3.98Å; Y582-Y816 HydrophobicContact CD2-CG 4.36Å; Y582-Y816 HydrophobicContact CG-CD1 4.35Å; Y582-Y816 HydrophobicContact CG-CE1 4.24Å; Y582-Y816 PolarHBondContact N-OH 3.36Å; L585-Y816 HydrophobicContact CD1-CD2 3.83Å; L585-Y816 HydrophobicContact CD1-CE2 3.67Å; F602-Y816 HydrophobicContact CD2-CG 4.33Å; F602-Y816 HydrophobicContact CE2-CD1 4.42Å; F602-Y816 AromaticContact CE2-CD2 3.69Å; F602-Y816 HydrophobicContact CE2-CD2 3.69Å; F602-Y816 AromaticContact CE2-CG 3.52Å; F602-Y816 HydrophobicContact CE2-CG 3.52Å; F602-Y816 HydrophobicContact CZ-CD1 4.35Å; F602-Y816 HydrophobicContact CZ-CD2 4.14Å; F602-Y816 AromaticContact CZ-CG 3.85Å; F602-Y816 HydrophobicContact CZ-CG 3.85Å; G603-Y816 PolarHBondContact N-O 2.84Å; G603-Y816 CarbonylContact O-C 3.53Å; G603-Y816 WeakPolarHBondContact O-CA 3.4Å; G603-Y816 WeakPolarHBondContact O-CB 3.31Å; L604-Y816 HydrophobicContact CD2-CE1 4.34Å; S812-Y816 WeakPolarHBondContact O-CE2 3.43Å; D813-Y816 PolarHBondContact O-N 3.05Å; D813-Y816 VanDerWaalsContact O-N 3.09Å; F814-Y816 PolarHBondContact O-N 3.08Å; F814-Y816 VanDerWaalsContact O-N 3.13Å; Y816-K818 PolarHBondContact O-N 3.36Å
817Y92.4Very high81.4Confident0 Ų028.9 Ų28.90%015%0.153CC..EExtended strand (participates in β ladder)trans-63.7126.4173172.5-97.6000111.3W600 N605 F814 G820 Y822 W859 L865 Q866W600-Y817 HydrophobicContact CB-CD2 3.99Å; W600-Y817 HydrophobicContact CB-CE2 3.87Å; W600-Y817 HydrophobicContact CD2-CD2 4.17Å; W600-Y817 AromaticContact CE3-CD2 3.79Å; W600-Y817 HydrophobicContact CE3-CD2 3.79Å; W600-Y817 HydrophobicContact CE3-CG 4.47Å; W600-Y817 HydrophobicContact CG-CD2 4.29Å; N605-Y817 PolarHBondContact ND2-O 2.86Å; F814-Y817 WeakPolarHBondContact O-CB 3.38Å; F814-Y817 PolarHBondContact O-N 2.89Å; Y817-G820 WeakPolarHBondContact CE2-O 3.41Å; Y817-G820 VanDerWaalsContact CZ-O 3.27Å; Y817-G820 PolarHBondContact OH-N 2.83Å; Y817-G820 PolarHBondContact OH-O 3.17Å; Y817-Y822 HydrophobicContact CD2-CD2 4.08Å; Y817-Y822 HydrophobicContact CD2-CG 4.33Å; Y817-W859 AromaticContact CD1-CH2 3.85Å; Y817-W859 HydrophobicContact CD1-CH2 3.85Å; Y817-W859 AromaticContact CD1-CZ2 3.85Å; Y817-W859 HydrophobicContact CD1-CZ2 3.85Å; Y817-W859 HydrophobicContact CD1-CZ3 4.44Å; Y817-W859 HydrophobicContact CE1-CH2 4.46Å; Y817-W859 HydrophobicContact CG-CZ2 4.4Å; Y817-L865 HydrophobicContact CD1-CD1 3.78Å; Y817-L865 HydrophobicContact CD2-CD1 4.12Å; Y817-L865 HydrophobicContact CE1-CB 4.26Å; Y817-L865 HydrophobicContact CE1-CD1 3.55Å; Y817-L865 HydrophobicContact CE2-CD1 3.9Å; Y817-L865 HydrophobicContact CG-CD1 4.05Å; Y817-Q866 PolarHBondContact OH-N 2.91Å
818K90.5Very high80.6Confident71 Ų7130.3 Ų30.331%0.30917%0.171SC..EExtended strand (participates in β ladder)trans-108.2-44.6175.1-60.6-62.4-62-177.20113.7K601 L604 N605 Y816 G860 E861K601-K818 HydrophobicContact CB-CB 4.13Å; K601-K818 VanDerWaalsContact O-CB 3.3Å; K601-K818 WeakPolarHBondContact O-CB 3.33Å; K601-K818 PolarHBondContact O-N 3.17Å; L604-K818 WeakPolarHBondContact O-CD 3.41Å; L604-K818 PolarHBondContact O-NZ 3.01Å; N605-K818 VanDerWaalsContact OD1-CD 3.26Å; N605-K818 WeakPolarHBondContact OD1-CD 2.86Å; N605-K818 PolarHBondContact OD1-NZ 2.94Å; Y816-K818 PolarHBondContact O-N 3.36Å; K818-G860 CarbonylContact O-C 3.51Å; K818-E861 PolarHBondContact O-N 3.13Å
819S90.4Very high80.5Confident26 Ų2635.6 Ų35.618%0.18219%0.194CC..EExtended strand (participates in β ladder)trans-170.5163.4-17554.10000111.7W600 K601 E861W600-S819 CarbonylContact C-O 3.57Å; W600-S819 WeakPolarHBondContact CA-O 3.38Å; W600-S819 WeakPolarHBondContact CB-O 3.49Å; K601-S819 WeakPolarHBondContact CD-OG 3.4Å; K601-S819 WeakPolarHBondContact CG-OG 3.37Å; K601-S819 PolarHBondContact N-O 2.83Å; S819-E861 VanDerWaalsContact CA-OE1 3.28Å; S819-E861 WeakPolarHBondContact CA-OE1 3.48Å; S819-E861 VanDerWaalsContact CB-OE1 3.27Å; S819-E861 WeakPolarHBondContact CB-OE1 3.09Å
820G87.9Confident80.4Confident18 Ų1835 Ų3519%0.18619%0.187CC..EExtended strand (participates in β ladder)trans91.7-168.6179.900000113.7S599 Y817 Y822 E861S599-G820 CarbonylContact O-C 3.4Å; S599-G820 VanDerWaalsContact O-CA 3.29Å; S599-G820 WeakPolarHBondContact O-CA 3.18Å; Y817-G820 WeakPolarHBondContact CE2-O 3.41Å; Y817-G820 VanDerWaalsContact CZ-O 3.27Å; Y817-G820 PolarHBondContact OH-N 2.83Å; Y817-G820 PolarHBondContact OH-O 3.17Å; G820-Y822 PolarHBondContact O-N 3.25Å; G820-E861 PolarHBondContact N-OE1 3.48Å
821V85.9Confident80Confident4 Ų435.7 Ų35.72%0.02419%0.194CC..EExtended strand (participates in β ladder)trans-87.1104.9-179.5-176.60000109.6S599 V823 Y848 Q866 F868S599-V821 WeakPolarHBondContact CB-O 3.44Å; S599-V821 PolarHBondContact O-N 3.1Å; S599-V821 PolarHBondContact OG-O 3.26Å; V821-V823 PolarHBondContact O-N 2.92Å; V821-Y848 HydrophobicContact CG2-CD1 3.93Å; V821-Y848 HydrophobicContact CG2-CG 4.18Å; V821-Q866 CarbonylContact C-O 3.44Å; V821-Q866 WeakPolarHBondContact CA-O 3.49Å; V821-Q866 HydrophobicContact CG2-CB 4.27Å; V821-F868 HydrophobicContact CG1-CD2 3.8Å; V821-F868 HydrophobicContact CG1-CE2 3.79Å
822Y83.2Confident80.1Confident13 Ų1333.4 Ų33.45%0.05119%0.187CC..EExtended strand (participates in β ladder)trans-64.9124177.2176.6-102.5000110.9W600 D813 F814 Y817 G820 H824 L865 Q866 S867W600-Y822 HydrophobicContact CD2-CD2 4.15Å; W600-Y822 AromaticContact CE2-CD2 3.93Å; W600-Y822 HydrophobicContact CH2-CD2 4.43Å; W600-Y822 HydrophobicContact CH2-CE2 4.29Å; W600-Y822 HydrophobicContact CZ2-CD2 4.08Å; W600-Y822 AromaticContact CZ2-CE2 3.98Å; W600-Y822 HydrophobicContact CZ2-CE2 3.98Å; D813-Y822 PolarHBondContact OD1-OH 2.87Å; F814-Y822 HydrophobicContact CB-CE2 4.3Å; F814-Y822 AromaticContact CD2-CD1 3.93Å; F814-Y822 HydrophobicContact CD2-CD1 3.93Å; F814-Y822 HydrophobicContact CD2-CD2 4.15Å; F814-Y822 AromaticContact CD2-CE1 3.68Å; F814-Y822 HydrophobicContact CD2-CE1 3.68Å; F814-Y822 AromaticContact CD2-CE2 3.91Å; F814-Y822 HydrophobicContact CD2-CE2 3.91Å; F814-Y822 HydrophobicContact CD2-CG 4.16Å; F814-Y822 AromaticContact CD2-CZ 3.68Å; F814-Y822 HydrophobicContact CE2-CD1 4.21Å; F814-Y822 HydrophobicContact CE2-CE1 4.33Å; F814-Y822 HydrophobicContact CE2-CG 4.47Å; Y817-Y822 HydrophobicContact CD2-CD2 4.08Å; Y817-Y822 HydrophobicContact CD2-CG 4.33Å; G820-Y822 PolarHBondContact O-N 3.25Å; Y822-H824 HydrophobicContact CE1-CB 4.44Å; Y822-L865 VanDerWaalsContact CB-CD1 3.49Å; Y822-L865 HydrophobicContact CG-CD1 4.19Å; Y822-Q866 PolarHBondContact N-O 3.49Å; Y822-S867 PolarHBondContact O-OG 3.39Å
823V77.3Confident80.5Confident40 Ų4033.1 Ų33.124%0.24219%0.185CC..  trans-129.4127.2165.9178.50000105.8W600 V821 K825 F868W600-V823 PolarHBondContact NE1-O 3.45Å; V821-V823 PolarHBondContact O-N 2.92Å; V823-K825 PolarHBondContact O-N 3.03Å; V823-F868 HydrophobicContact CG2-CD2 3.71Å; V823-F868 HydrophobicContact CG2-CE2 4.12Å
824H73.6Confident80.9Confident53 Ų5333.1 Ų33.125%0.24519%0.185CC..  trans-56.7130.3174.9170.360.4000110.7Y811 D813 Y822 K826 G827Y811-H824 VanDerWaalsContact CB-ND1 3.31Å; Y811-H824 WeakPolarHBondContact CB-ND1 3.43Å; Y811-H824 AromaticContact CD1-CD2 3.92Å; Y811-H824 AromaticContact CD1-CE1 3.44Å; Y811-H824 VanDerWaalsContact CD1-CE1 3.44Å; Y811-H824 WeakPolarHBondContact CD1-CE1 3.37Å; Y811-H824 AromaticContact CD1-ND1 3.82Å; Y811-H824 AromaticContact CD1-NE2 3.53Å; Y811-H824 HydrophobicContact CD2-CB 4.24Å; Y811-H824 AromaticContact CD2-CG 3.95Å; Y811-H824 AromaticContact CE1-NE2 3.89Å; Y811-H824 HydrophobicContact CG-CB 4.49Å; Y811-H824 AromaticContact CG-CE1 3.59Å; Y811-H824 AromaticContact CG-CG 3.76Å; Y811-H824 AromaticContact CG-ND1 3.47Å; Y811-H824 AromaticContact CG-NE2 4Å; D813-H824 IonicContact OD1-CE1 3.91Å; D813-H824 IonicContact OD1-ND1 2.64Å; D813-H824 PolarHBondContact OD1-ND1 3.15Å; D813-H824 VanDerWaalsContact OD1-ND1 3.11Å; D813-H824 IonicContact OD2-CE1 3.23Å; D813-H824 IonicContact OD2-CG 2.66Å; D813-H824 IonicContact OD2-ND1 3.64Å; D813-H824 PolarHBondContact OD2-ND1 3.48Å; D813-H824 VanDerWaalsContact OD2-ND1 3.11Å; Y822-H824 HydrophobicContact CE1-CB 4.44Å; H824-K826 PolarHBondContact CE1-O 3.32Å; H824-K826 PolarHBondContact ND1-O 2.98Å; H824-G827 PolarHBondContact CE1-O 3.17Å; H824-G827 PolarHBondContact NE2-O 3.18Å
825K71.4Confident81Confident116 Ų11633.2 Ų33.250%0.50419%0.186SC..  trans-121.7-36.5179.6-63.1-65.8-176.4174.10112.4F589 D813 V823F589-K825 HydrophobicContact CZ-CB 4.2Å; D813-K825 PolarHBondContact OD2-N 3.42Å; V823-K825 PolarHBondContact O-N 3.03Å
826K70Confident81.1Confident89 Ų8933.7 Ų33.739%0.38719%0.188SC..SBendtrans-148.1152.6-171.6-72.6-66.1-175.7176.80112.6L585 D813 H824L585-K826 HydrophobicContact CD2-CB 3.89Å; D813-K826 WeakPolarHBondContact CB-O 3.45Å; D813-K826 PolarHBondContact OD2-N 3.42Å; H824-K826 PolarHBondContact CE1-O 3.32Å; H824-K826 PolarHBondContact ND1-O 2.98Å
827G61.7Low81.1Confident36 Ų3633.7 Ų33.737%0.37119%0.188SC..SBendtrans95.4161.217700000114.7S812 H824S812-G827 VanDerWaalsContact OG-CA 3.25Å; S812-G827 WeakPolarHBondContact OG-CA 3.45Å; H824-G827 PolarHBondContact CE1-O 3.17Å; H824-G827 PolarHBondContact NE2-O 3.18Å
828G64.8Low81.2Confident43 Ų4333.8 Ų33.844%0.44319%0.188SC..  trans-85.6165.3178.900000113.2Y811 S812Y811-G828 VanDerWaalsContact CA-O 3.29Å; Y811-G828 WeakPolarHBondContact CA-O 3.48Å; S812-G828 PolarHBondContact N-O 2.99Å; S812-G828 VanDerWaalsContact N-O 3.09Å
829K70.2Confident81.4Confident124 Ų12430.4 Ų30.454%0.53917%0.173SC..EExtended strand (participates in β ladder)trans-66.6128.3169179.3178.6178.3176.80109.5A809 Y811 N832A809-K829 HydrophobicContact CB-CD 3.93Å; A809-K829 HydrophobicContact CB-CG 4.19Å; Y811-K829 HydrophobicContact CD1-CB 4.29Å; Y811-K829 HydrophobicContact CE1-CB 4.08Å; K829-N832 WeakPolarHBondContact CE-OD1 3.23Å; K829-N832 PolarHBondContact NZ-OD1 3.42Å; K829-N832 VanDerWaalsContact NZ-OD1 3.1Å
830I72Confident81.5Confident16 Ų1629.8 Ų29.88%0.08217%0.167CC..EExtended strand (participates in β ladder)trans-102.9-33.5-178.5-60.4-178.2000111.8F613 K617 L620 V810 S812 Y815F613-I830 HydrophobicContact CE2-CD1 3.72Å; F613-I830 HydrophobicContact CE2-CG1 4.1Å; F613-I830 HydrophobicContact CE2-CG2 4.02Å; F613-I830 HydrophobicContact CZ-CD1 4.42Å; F613-I830 HydrophobicContact CZ-CG1 4.33Å; F613-I830 HydrophobicContact CZ-CG2 3.89Å; K617-I830 HydrophobicContact CB-CG2 3.98Å; K617-I830 HydrophobicContact CD-CG2 3.86Å; K617-I830 VanDerWaalsContact CE-O 3.28Å; K617-I830 WeakPolarHBondContact CE-O 3.24Å; K617-I830 HydrophobicContact CG-CG2 3.8Å; L620-I830 HydrophobicContact CD1-CB 4.01Å; L620-I830 HydrophobicContact CD1-CG2 3.7Å; V810-I830 PolarHBondContact O-N 3.18Å; S812-I830 VanDerWaalsContact CB-CD1 3.49Å; Y815-I830 HydrophobicContact CD2-CD1 4.28Å; Y815-I830 HydrophobicContact CE2-CD1 3.39Å
831G73.4Confident81.6Confident15 Ų1529 Ų2916%0.15516%0.159CC..EExtended strand (participates in β ladder)trans177.1-169.9-177.200000112.2V810V810-G831 PolarHBondContact N-O 3.44Å
832N81.2Confident81.6Confident32 Ų3232.1 Ų32.117%0.17117%0.172CC..EExtended strand (participates in β ladder)trans-114.1139.7176.5-52.7-60000109.4L620 V622 F624 I807 F808 K829L620-N832 CarbonylContact C-O 3.56Å; V622-N832 HydrophobicContact CB-CB 3.99Å; V622-N832 HydrophobicContact CG1-CB 4.26Å; V622-N832 PolarHBondContact N-O 3.05Å; F624-N832 HydrophobicContact CE2-CB 4.26Å; F624-N832 WeakPolarHBondContact CE2-ND2 3.44Å; I807-N832 HydrophobicContact CG2-CB 4.21Å; F808-N832 WeakPolarHBondContact O-CA 3.21Å; K829-N832 WeakPolarHBondContact CE-OD1 3.23Å; K829-N832 PolarHBondContact NZ-OD1 3.42Å; K829-N832 VanDerWaalsContact NZ-OD1 3.1Å
833H89.4Confident81.3Confident0 Ų035.2 Ų35.20%019%0.193CC..EExtended strand (participates in β ladder)trans-130.3141.9-176.8-169.252.9000110.7L619 L620 Q668 C674 I807 F808 V810 N853 W855L619-H833 PolarHBondContact O-ND1 2.67Å; L620-H833 HydrophobicContact CD2-CB 3.97Å; Q668-H833 PolarHBondContact OE1-CE1 2.99Å; C674-H833 WeakPolarHBondContact CB-CE1 3.44Å; C674-H833 VanDerWaalsContact CB-ND1 3.34Å; C674-H833 WeakPolarHBondContact CB-ND1 3.46Å; C674-H833 PolarHBondContact SG-ND1 2.77Å; I807-H833 WeakPolarHBondContact CA-O 3.21Å; F808-H833 HydrophobicContact CD1-CB 4.48Å; F808-H833 WeakPolarHBondContact CD1-O 3.39Å; F808-H833 HydrophobicContact CE1-CB 3.93Å; F808-H833 AromaticContact CE1-CD2 3.85Å; F808-H833 HydrophobicContact CZ-CB 4.31Å; F808-H833 PolarHBondContact N-O 3.47Å; F808-H833 PolarHBondContact O-N 2.89Å; V810-H833 HydrophobicContact CG2-CB 3.44Å; V810-H833 VanDerWaalsContact CG2-CB 3.44Å; H833-N853 PolarHBondContact NE2-OD1 2.86Å; H833-W855 AromaticContact CE1-NE1 3.61Å; H833-W855 AromaticContact NE2-CE2 3.98Å; H833-W855 AromaticContact NE2-NE1 3.77Å
834A89.9Confident81.2Confident0 Ų036.4 Ų36.40%021%0.213CC..EExtended strand (participates in β ladder)trans-102.1131.4176.600000110.1V622 S678 P720 I805 A806 I807V622-A834 HydrophobicContact CG2-CB 3.58Å; S678-A834 VanDerWaalsContact OG-CB 3.3Å; S678-A834 WeakPolarHBondContact OG-CB 3.48Å; P720-A834 HydrophobicContact CG-CB 3.83Å; I805-A834 HydrophobicContact CG2-CB 4.49Å; A806-A834 CarbonylContact O-C 3.56Å; A806-A834 WeakPolarHBondContact O-CA 3.31Å; I807-A834 HydrophobicContact CG1-CB 4.36Å
835V91.5Very high81.2Confident2 Ų241.1 Ų41.11%0.01224%0.24CC..EExtended strand (participates in β ladder)trans-133.7163.1-178-71.90000111I805 A806 F808 V851 L869I805-V835 WeakPolarHBondContact CA-O 3.47Å; A806-V835 HydrophobicContact CB-CG2 4.21Å; A806-V835 PolarHBondContact N-O 2.84Å; A806-V835 PolarHBondContact O-N 2.76Å; F808-V835 HydrophobicContact CD1-CG1 4.46Å; F808-V835 HydrophobicContact CD1-CG2 3.84Å; F808-V835 HydrophobicContact CE1-CB 4.33Å; F808-V835 HydrophobicContact CE1-CG1 3.61Å; F808-V835 HydrophobicContact CE1-CG2 3.78Å; F808-V835 HydrophobicContact CZ-CG1 4.44Å; V835-V851 HydrophobicContact CB-CG1 3.5Å; V835-V851 HydrophobicContact CG1-CG1 4.07Å; V835-V851 HydrophobicContact CG2-CG1 3.57Å; V835-L869 HydrophobicContact CG2-CD1 4.39Å
836R93.5Very high81.3Confident9 Ų939.5 Ų39.53%0.03423%0.234CC..EExtended strand (participates in β ladder)trans-102.5117175.8174.7176.963.6169.1-0.5109.6I662 I664 V682 D685 P803 V804 I838 A852I662-R836 PolarHBondContact O-NH2 2.65Å; I664-R836 PolarHBondContact O-NH2 3.37Å; V682-R836 HydrophobicContact CG2-CB 4.21Å; V682-R836 HydrophobicContact CG2-CG 3.68Å; D685-R836 IonicContact OD1-NH1 3.92Å; D685-R836 PolarHBondContact OD1-NH1 2.88Å; D685-R836 WeakPolarHBondContact OD2-CD 3.45Å; D685-R836 IonicContact OD2-CZ 3.34Å; D685-R836 IonicContact OD2-NE 2.81Å; D685-R836 IonicContact OD2-NH1 3.03Å; D685-R836 PolarHBondContact OD2-NH1 2.74Å; P803-R836 HydrophobicContact CB-CG 4Å; V804-R836 CarbonylContact O-C 2.92Å; V804-R836 WeakPolarHBondContact O-CA 3.47Å; R836-I838 HydrophobicContact CG-CG2 3.92Å; R836-A852 PolarHBondContact N-O 3.3Å; R836-A852 PolarHBondContact O-N 2.91Å
837I92.1Very high81.8Confident0 Ų039.7 Ų39.70%024%0.235CC..EExtended strand (participates in β ladder)trans-87.2126.7172.2-50.6-177.5000108.5I798 P803 V804 A806 G839 W849 V851 L869 I873I798-I837 HydrophobicContact CD1-CB 4.2Å; I798-I837 HydrophobicContact CD1-CG2 3.57Å; P803-I837 CarbonylContact C-O 3.49Å; P803-I837 WeakPolarHBondContact CA-O 3.48Å; P803-I837 VanDerWaalsContact CB-O 3.32Å; P803-I837 WeakPolarHBondContact CB-O 3.15Å; V804-I837 HydrophobicContact CG2-CB 3.71Å; V804-I837 HydrophobicContact CG2-CD1 4.19Å; V804-I837 HydrophobicContact CG2-CG1 4.17Å; V804-I837 PolarHBondContact N-O 3.11Å; V804-I837 PolarHBondContact O-N 3.16Å; A806-I837 HydrophobicContact CB-CD1 3.54Å; A806-I837 HydrophobicContact CB-CG1 3.81Å; I837-G839 WeakPolarHBondContact CG2-O 3.32Å; I837-W849 HydrophobicContact CD1-CB 4.41Å; I837-W849 HydrophobicContact CD1-CD2 4.26Å; I837-W849 HydrophobicContact CD1-CG 4.21Å; I837-W849 HydrophobicContact CG2-CB 4.07Å; I837-W849 HydrophobicContact CG2-CD2 4.35Å; I837-W849 HydrophobicContact CG2-CE3 3.85Å; I837-W849 HydrophobicContact CG2-CG 4.48Å; I837-V851 HydrophobicContact CG1-CG2 4.24Å; I837-L869 HydrophobicContact CD1-CD1 3.99Å; I837-L869 HydrophobicContact CG1-CD1 4.35Å; I837-I873 HydrophobicContact CD1-CD1 4.44Å
838I95Very high82.9Confident2 Ų239.7 Ų39.71%0.0122%0.224CC..EExtended strand (participates in β ladder)trans-1142.8-176.262166.8000112.9A651 I662 P803 R836 L850 A852A651-I838 WeakPolarHBondContact CB-O 3.42Å; A651-I838 PolarHBondContact N-O 3.18Å; I662-I838 HydrophobicContact CG2-CB 4.29Å; I662-I838 HydrophobicContact CG2-CG2 4.05Å; P803-I838 HydrophobicContact CB-CG2 4.12Å; P803-I838 HydrophobicContact CG-CB 4.35Å; P803-I838 HydrophobicContact CG-CG2 3.98Å; R836-I838 HydrophobicContact CG-CG2 3.92Å; I838-L850 HydrophobicContact CD1-CD2 3.9Å; I838-L850 HydrophobicContact CD1-CG 4.02Å; I838-L850 HydrophobicContact CG1-CB 4.33Å; I838-L850 HydrophobicContact CG1-CD2 3.89Å; I838-L850 HydrophobicContact CG1-CG 3.78Å; I838-L850 WeakPolarHBondContact CG1-O 3.45Å; I838-L850 PolarHBondContact N-O 3.31Å; I838-A852 HydrophobicContact CG2-CB 4.26Å
839G94.1Very high84.1Confident0 Ų038.4 Ų38.40%021%0.206CC..EExtended strand (participates in β ladder)trans168.3-174.2-17500000113.3L649 I837 L850L649-G839 CarbonylContact O-C 3.5Å; L649-G839 WeakPolarHBondContact O-CA 3.4Å; I837-G839 WeakPolarHBondContact CG2-O 3.32Å; G839-L850 PolarHBondContact N-O 3.14Å; G839-L850 PolarHBondContact O-N 2.9Å
840W93.4Very high85.2Confident14 Ų1433.4 Ų33.45%0.05319%0.185CC..EExtended strand (participates in β ladder)trans-149.8165.6173.266.787.7000109.8L645 P646 E647 E648 L649 M795 I798 N799 Y848 W849L645-W840 HydrophobicContact CB-CZ2 4.41Å; P646-W840 HydrophobicContact CG-CZ2 3.97Å; P646-W840 WeakPolarHBondContact O-CZ2 3.09Å; P646-W840 PolarHBondContact O-NE1 3Å; E647-W840 PolarHBondContact O-NE1 3.41Å; E648-W840 WeakPolarHBondContact CA-O 3.39Å; L649-W840 HydrophobicContact CB-CD2 3.9Å; L649-W840 HydrophobicContact CB-CE3 3.85Å; L649-W840 HydrophobicContact CB-CH2 3.52Å; L649-W840 HydrophobicContact CB-CZ2 3.54Å; L649-W840 HydrophobicContact CB-CZ3 3.64Å; L649-W840 HydrophobicContact CD1-CH2 3.46Å; L649-W840 VanDerWaalsContact CD1-CH2 3.46Å; L649-W840 HydrophobicContact CD1-CZ2 4.14Å; L649-W840 HydrophobicContact CD1-CZ3 3.82Å; L649-W840 HydrophobicContact CD2-CE3 4.31Å; L649-W840 HydrophobicContact CD2-CH2 4.33Å; L649-W840 HydrophobicContact CD2-CZ3 3.85Å; L649-W840 HydrophobicContact CG-CH2 3.95Å; L649-W840 HydrophobicContact CG-CZ2 4.42Å; L649-W840 HydrophobicContact CG-CZ3 3.97Å; L649-W840 PolarHBondContact N-O 2.88Å; L649-W840 PolarHBondContact O-N 3.12Å; M795-W840 HydrophobicContact CB-CD2 4.41Å; M795-W840 HydrophobicContact CB-CE3 4.29Å; M795-W840 HydrophobicContact CB-CH2 4.03Å; M795-W840 HydrophobicContact CB-CZ2 4.17Å; M795-W840 HydrophobicContact CB-CZ3 4.13Å; M795-W840 HydrophobicContact CE-CD2 4.13Å; M795-W840 VanDerWaalsContact CE-CE2 3.46Å; M795-W840 HydrophobicContact CE-CG 4.24Å; M795-W840 HydrophobicContact CE-CZ2 3.84Å; M795-W840 HydrophobicContact CG-CD2 3.98Å; M795-W840 HydrophobicContact CG-CE3 4.2Å; M795-W840 HydrophobicContact CG-CG 4.35Å; M795-W840 HydrophobicContact CG-CZ2 4.43Å; M795-W840 VanDerWaalsContact O-CH2 3.31Å; M795-W840 WeakPolarHBondContact O-CH2 3.23Å; M795-W840 VanDerWaalsContact O-CZ3 3.28Å; M795-W840 WeakPolarHBondContact O-CZ3 3.06Å; I798-W840 HydrophobicContact CB-CE3 4.22Å; I798-W840 HydrophobicContact CB-CZ3 3.71Å; I798-W840 HydrophobicContact CD1-CE3 4.29Å; I798-W840 HydrophobicContact CG2-CE3 4.06Å; I798-W840 HydrophobicContact CG2-CZ3 3.67Å; N799-W840 HydrophobicContact CB-CH2 3.98Å; W840-Y848 CarbonylContact C-O 3.54Å; W840-Y848 WeakPolarHBondContact CA-O 3.41Å; W840-Y848 WeakPolarHBondContact CB-O 3.3Å; W840-W849 HydrophobicContact CB-CE3 3.79Å; W840-W849 HydrophobicContact CB-CZ3 3.96Å; W840-W849 HydrophobicContact CE3-CZ3 4.41Å
841G90Very high86.2Confident2 Ų232.7 Ų32.72%0.02118%0.181CC..EExtended strand (participates in β ladder)trans-166.1-169.8171.900000112.1K847 Y848G841-K847 CarbonylContact O-C 3.42Å; G841-K847 WeakPolarHBondContact O-CA 3.18Å; G841-Y848 PolarHBondContact N-O 3.37Å; G841-Y848 WeakPolarHBondContact O-CD1 3.47Å; G841-Y848 PolarHBondContact O-N 3.01Å
842K85.5Confident87.2Confident69 Ų6932.1 Ų32.130%0.318%0.175SC..EExtended strand (participates in β ladder)trans-141.6124.3-177.8-171-175.7178.1-1680110.5E648 G844 E846 K847 Y848E648-K842 PolarHBondContact OE1-N 3.25Å; K842-G844 WeakPolarHBondContact CE-O 3.41Å; K842-G844 WeakPolarHBondContact CG-O 3.39Å; K842-E846 CarbonylContact C-O 3.57Å; K842-E846 WeakPolarHBondContact CA-O 3.46Å; K842-K847 HydrophobicContact CG-CG 4.29Å; K842-Y848 VanDerWaalsContact N-CE1 3.33Å
843T77.8Confident87.8Confident78 Ų7830.9 Ų30.948%0.47917%0.169SC..EExtended strand (participates in β ladder)trans-105.5108.4172.3-59.60000108.8N845 E846 Y848T843-N845 PolarHBondContact O-N 3.26Å; T843-E846 PolarHBondContact N-O 2.91Å; T843-E846 PolarHBondContact O-N 3.41Å; T843-Y848 WeakPolarHBondContact OG1-CE1 3.26Å
844G75Confident88.1Confident65 Ų6531.1 Ų31.167%0.6717%0.17SC*.THydrogen-bonded Turntrans64.9-117.7-172.700000110.8K842K842-G844 WeakPolarHBondContact CE-O 3.41Å; K842-G844 WeakPolarHBondContact CG-O 3.39Å
845N72.6Confident88.3Confident151 Ų15131.2 Ų31.281%0.80717%0.171SC*.THydrogen-bonded Turntrans-97.2-3.9172-78.7-18.7000113.6T843T843-N845 PolarHBondContact O-N 3.26Å
846E73.7Confident88.3Confident82 Ų8231.4 Ų31.438%0.38317%0.173SC..EExtended strand (participates in β ladder)trans-92.4115.7-175.5-65.2-173159.800111.2S599 K842 T843 F868S599-E846 WeakPolarHBondContact CB-OE2 3.21Å; K842-E846 CarbonylContact C-O 3.57Å; K842-E846 WeakPolarHBondContact CA-O 3.46Å; T843-E846 PolarHBondContact N-O 2.91Å; T843-E846 PolarHBondContact O-N 3.41Å; E846-F868 HydrophobicContact CB-CE2 3.99Å; E846-F868 HydrophobicContact CB-CZ 3.8Å; E846-F868 HydrophobicContact CG-CE2 4.41Å; E846-F868 HydrophobicContact CG-CZ 4.27Å
847K81.2Confident88.2Confident94 Ų9435.2 Ų35.241%0.40919%0.194SC..EExtended strand (participates in β ladder)trans-78.7150.2172.9-60.8-175.6-178.3178.90111E791 G841 K842 F868E791-K847 WeakPolarHBondContact OE1-CD 3.44Å; E791-K847 WeakPolarHBondContact OE1-CE 3.09Å; E791-K847 IonicContact OE1-NZ 3.56Å; E791-K847 PolarHBondContact OE1-NZ 2.92Å; E791-K847 IonicContact OE2-NZ 3.91Å; E791-K847 PolarHBondContact OE2-NZ 3Å; G841-K847 CarbonylContact O-C 3.42Å; G841-K847 WeakPolarHBondContact O-CA 3.18Å; K842-K847 HydrophobicContact CG-CG 4.29Å; K847-F868 HydrophobicContact CB-CE1 4.34Å; K847-F868 WeakPolarHBondContact O-CD1 3.43Å; K847-F868 WeakPolarHBondContact O-CE1 3.46Å; K847-F868 VanDerWaalsContact O-CE2 3.27Å; K847-F868 WeakPolarHBondContact O-CE2 3.18Å; K847-F868 WeakPolarHBondContact O-CZ 3.35Å
848Y84.2Confident88Confident35 Ų3541.3 Ų41.314%0.13722%0.217CC..EExtended strand (participates in β ladder)trans-146.4150.517764.4-93.7000112V821 W840 G841 K842 T843 Q866V821-Y848 HydrophobicContact CG2-CD1 3.93Å; V821-Y848 HydrophobicContact CG2-CG 4.18Å; W840-Y848 CarbonylContact C-O 3.54Å; W840-Y848 WeakPolarHBondContact CA-O 3.41Å; W840-Y848 WeakPolarHBondContact CB-O 3.3Å; G841-Y848 PolarHBondContact N-O 3.37Å; G841-Y848 WeakPolarHBondContact O-CD1 3.47Å; G841-Y848 PolarHBondContact O-N 3.01Å; K842-Y848 VanDerWaalsContact N-CE1 3.33Å; T843-Y848 WeakPolarHBondContact OG1-CE1 3.26Å; Y848-Q866 HydrophobicContact CD2-CB 3.64Å; Y848-Q866 HydrophobicContact CD2-CG 3.79Å; Y848-Q866 HydrophobicContact CE2-CB 4.24Å; Y848-Q866 HydrophobicContact CE2-CG 3.86Å; Y848-Q866 HydrophobicContact CG-CB 3.96Å; Y848-Q866 HydrophobicContact CG-CG 4.47Å
849W89.9Confident87.9Confident17 Ų1741.3 Ų41.36%0.06422%0.217CC..EExtended strand (participates in β ladder)trans-84.4137.1163.6-61.3109000110E791 I794 M795 I798 I837 W840 V851 Q866 S867 L869E791-W849 HydrophobicContact CG-CH2 4.16Å; E791-W849 HydrophobicContact CG-CZ2 3.92Å; I794-W849 HydrophobicContact CB-CH2 3.58Å; I794-W849 HydrophobicContact CB-CZ2 4.09Å; I794-W849 HydrophobicContact CB-CZ3 4.25Å; I794-W849 HydrophobicContact CD1-CH2 4.2Å; I794-W849 HydrophobicContact CD1-CZ2 3.81Å; I794-W849 HydrophobicContact CG2-CE3 4.4Å; I794-W849 HydrophobicContact CG2-CH2 3.48Å; I794-W849 VanDerWaalsContact CG2-CH2 3.48Å; I794-W849 HydrophobicContact CG2-CZ2 4.04Å; I794-W849 HydrophobicContact CG2-CZ3 3.69Å; M795-W849 HydrophobicContact CG-CH2 3.68Å; M795-W849 HydrophobicContact CG-CZ3 3.9Å; I798-W849 HydrophobicContact CD1-CE3 4.16Å; I798-W849 HydrophobicContact CD1-CZ3 3.86Å; I837-W849 HydrophobicContact CD1-CB 4.41Å; I837-W849 HydrophobicContact CD1-CD2 4.26Å; I837-W849 HydrophobicContact CD1-CG 4.21Å; I837-W849 HydrophobicContact CG2-CB 4.07Å; I837-W849 HydrophobicContact CG2-CD2 4.35Å; I837-W849 HydrophobicContact CG2-CE3 3.85Å; I837-W849 HydrophobicContact CG2-CG 4.48Å; W840-W849 HydrophobicContact CB-CE3 3.79Å; W840-W849 HydrophobicContact CB-CZ3 3.96Å; W840-W849 HydrophobicContact CE3-CZ3 4.41Å; W849-V851 HydrophobicContact CB-CG2 3.9Å; W849-Q866 VanDerWaalsContact O-CA 3.31Å; W849-Q866 WeakPolarHBondContact O-CA 3.48Å; W849-S867 PolarHBondContact N-O 3.34Å; W849-S867 PolarHBondContact O-N 3.26Å; W849-S867 VanDerWaalsContact O-N 3.1Å; W849-L869 HydrophobicContact CB-CD1 4.48Å; W849-L869 PolarHBondContact NE1-O 3.33Å
850L93.1Very high87.8Confident19 Ų1941.8 Ų41.810%0.09922%0.222CC..EExtended strand (participates in β ladder)trans-90.2112.7170-17765.4000109.1I838 G839 Q866I838-L850 HydrophobicContact CD1-CD2 3.9Å; I838-L850 HydrophobicContact CD1-CG 4.02Å; I838-L850 HydrophobicContact CG1-CB 4.33Å; I838-L850 HydrophobicContact CG1-CD2 3.89Å; I838-L850 HydrophobicContact CG1-CG 3.78Å; I838-L850 WeakPolarHBondContact CG1-O 3.45Å; I838-L850 PolarHBondContact N-O 3.31Å; G839-L850 PolarHBondContact N-O 3.14Å; G839-L850 PolarHBondContact O-N 2.9Å; L850-Q866 HydrophobicContact CD1-CG 4.34Å
851V93.8Very high87.6Confident0 Ų043.9 Ų43.90%023%0.233CC..EExtended strand (participates in β ladder)trans-119.4130.9-167.7-1760000110.7V835 I837 W849 K864 L865 L869V835-V851 HydrophobicContact CB-CG1 3.5Å; V835-V851 HydrophobicContact CG1-CG1 4.07Å; V835-V851 HydrophobicContact CG2-CG1 3.57Å; I837-V851 HydrophobicContact CG1-CG2 4.24Å; W849-V851 HydrophobicContact CB-CG2 3.9Å; V851-K864 CarbonylContact O-C 3.54Å; V851-K864 VanDerWaalsContact O-CA 3.3Å; V851-K864 WeakPolarHBondContact O-CA 3.37Å; V851-L865 HydrophobicContact CB-CB 4.12Å; V851-L865 HydrophobicContact CB-CD2 4.3Å; V851-L865 HydrophobicContact CB-CG 4.49Å; V851-L865 HydrophobicContact CG1-CD2 4.48Å; V851-L865 HydrophobicContact CG2-CD2 4.5Å; V851-L865 PolarHBondContact N-O 2.78Å; V851-L865 PolarHBondContact O-N 2.99Å; V851-L869 HydrophobicContact CG2-CD1 3.84Å
852A94.1Very high87.6Confident4 Ų448.3 Ų48.33%0.03326%0.256CS..EExtended strand (participates in β ladder)trans-94.6112.6167.600000109.1I665 R836 I838I665-A852 HydrophobicContact CD1-CB 3.74Å; R836-A852 PolarHBondContact N-O 3.3Å; R836-A852 PolarHBondContact O-N 2.91Å; I838-A852 HydrophobicContact CG2-CB 4.26Å
853N94.8Very high87.6Confident6 Ų645 Ų453%0.03224%0.241CC..  trans-84173.2176.7-161.92.5000110.8I665 H833 W855 W859 G863I665-N853 WeakPolarHBondContact CG2-O 3.42Å; H833-N853 PolarHBondContact NE2-OD1 2.86Å; N853-W855 VanDerWaalsContact ND2-CD2 3.25Å; N853-W859 HydrophobicContact CB-CE3 4.14Å; N853-W859 HydrophobicContact CB-CZ3 3.7Å; N853-W859 WeakPolarHBondContact ND2-CH2 3.49Å; N853-W859 WeakPolarHBondContact ND2-CZ3 3.5Å; N853-G863 WeakPolarHBondContact CB-O 3.27Å; N853-G863 PolarHBondContact N-O 3.26Å; N853-G863 VanDerWaalsContact N-O 3.1Å
854S94.4Very high88.2Confident5 Ų543.4 Ų43.44%0.03523%0.228CC..SBendtrans-112.627.7-179.551.30000113.3K666 Q668K666-S854 CarbonylContact O-C 3.58Å; K666-S854 VanDerWaalsContact O-CA 3.25Å; K666-S854 WeakPolarHBondContact O-CA 3.1Å; Q668-S854 WeakPolarHBondContact CG-O 3.49Å; Q668-S854 PolarHBondContact N-O 3.12Å; Q668-S854 PolarHBondContact OE1-O 3.13Å; Q668-S854 PolarHBondContact OE1-OG 2.98Å
855W93.8Very high88.8Confident1 Ų140.3 Ų40.30%0.00420%0.196CC..BIsolated β-bridgetrans-105.213.6-179.5-64.6-13.9000113.6R607 F608 L620 F814 Y815 H833 N853 W859R607-W855 WeakPolarHBondContact CD-O 3.42Å; R607-W855 HydrophobicContact CG-CB 4.37Å; F608-W855 HydrophobicContact CE1-CE3 4.48Å; F608-W855 HydrophobicContact CE2-CE3 4.01Å; F608-W855 AromaticContact CE2-CZ3 3.98Å; F608-W855 HydrophobicContact CE2-CZ3 3.98Å; F608-W855 AromaticContact CZ-CD2 3.83Å; F608-W855 HydrophobicContact CZ-CD2 3.83Å; F608-W855 AromaticContact CZ-CE3 3.41Å; F608-W855 HydrophobicContact CZ-CE3 3.41Å; F608-W855 VanDerWaalsContact CZ-CE3 3.41Å; F608-W855 HydrophobicContact CZ-CH2 4.04Å; F608-W855 HydrophobicContact CZ-CZ2 4.44Å; F608-W855 AromaticContact CZ-CZ3 3.53Å; F608-W855 HydrophobicContact CZ-CZ3 3.53Å; L620-W855 HydrophobicContact CD2-CZ2 3.92Å; F814-W855 AromaticContact CD1-CH2 3.59Å; F814-W855 HydrophobicContact CD1-CH2 3.59Å; F814-W855 AromaticContact CD1-CZ3 3.75Å; F814-W855 HydrophobicContact CD1-CZ3 3.75Å; F814-W855 AromaticContact CE1-CH2 3.54Å; F814-W855 HydrophobicContact CE1-CH2 3.54Å; F814-W855 HydrophobicContact CE1-CZ2 4.46Å; F814-W855 AromaticContact CE1-CZ3 3.54Å; F814-W855 HydrophobicContact CE1-CZ3 3.54Å; Y815-W855 AromaticContact CD1-CH2 3.76Å; Y815-W855 HydrophobicContact CD1-CH2 3.76Å; Y815-W855 HydrophobicContact CD1-CZ3 4.08Å; Y815-W855 AromaticContact CE1-CH2 3.73Å; Y815-W855 HydrophobicContact CE1-CH2 3.73Å; Y815-W855 HydrophobicContact CE1-CZ2 4.23Å; Y815-W855 HydrophobicContact CE1-CZ3 4.49Å; H833-W855 AromaticContact CE1-NE1 3.61Å; H833-W855 AromaticContact NE2-CE2 3.98Å; H833-W855 AromaticContact NE2-NE1 3.77Å; N853-W855 VanDerWaalsContact ND2-CD2 3.25Å; W855-W859 HydrophobicContact CB-CB 4.35Å; W855-W859 AromaticContact CE3-CD1 3.89Å; W855-W859 AromaticContact CE3-CD2 3.58Å; W855-W859 HydrophobicContact CE3-CD2 3.58Å; W855-W859 AromaticContact CE3-CE2 3.53Å; W855-W859 HydrophobicContact CE3-CE3 4.15Å; W855-W859 AromaticContact CE3-CG 3.81Å; W855-W859 HydrophobicContact CE3-CG 3.81Å; W855-W859 HydrophobicContact CE3-CZ2 4.05Å; W855-W859 AromaticContact CE3-NE1 3.72Å; W855-W859 HydrophobicContact CZ3-CD2 4.15Å; W855-W859 AromaticContact CZ3-CE2 3.58Å; W855-W859 HydrophobicContact CZ3-CG 4.5Å; W855-W859 AromaticContact CZ3-CZ2 3.82Å; W855-W859 HydrophobicContact CZ3-CZ2 3.82Å; W855-W859 AromaticContact CZ3-NE1 3.64Å
856G91.3Very high89.1Confident6 Ų634.7 Ų34.76%0.06217%0.165CC..  trans69.9-175.4-176.900000114K666 R858 G863K666-G856 PolarHBondContact O-N 2.99Å; K666-G856 VanDerWaalsContact O-N 3.17Å; G856-R858 VanDerWaalsContact C-N 3.29Å; G856-R858 PolarHBondContact O-N 2.93Å; G856-G863 VanDerWaalsContact O-CA 3.27Å; G856-G863 WeakPolarHBondContact O-CA 3.46Å
857N91.7Very high89.1Confident89 Ų8930.9 Ų30.948%0.47615%0.147SC..THydrogen-bonded Turntrans-79.5-6.2-169.9-72.8-1.3000114.7I665 W859 N862I665-N857 WeakPolarHBondContact CB-OD1 3.27Å; N857-W859 VanDerWaalsContact C-N 3.33Å; N857-N862 WeakPolarHBondContact CB-OD1 3.4Å
858R89.2Confident88Confident129 Ų12931.2 Ų31.249%0.48715%0.149SC..THydrogen-bonded Turntrans-91.811.6-177.5-64.4-169.1-66.7168.1-2113.9D606 R607 G856D606-R858 HydrophobicContact CB-CB 4.39Å; R607-R858 HydrophobicContact CB-CB 4.44Å; G856-R858 VanDerWaalsContact C-N 3.29Å; G856-R858 PolarHBondContact O-N 2.93Å
859W92.9Very high86.5Confident1 Ų130.4 Ų30.40%0.00415%0.147CC..SBendtrans-133145.2177.4175.786.1000110.5N605 R607 F608 F814 Y817 N853 W855 N857 G863 L865N605-W859 VanDerWaalsContact ND2-CD1 3.33Å; R607-W859 HydrophobicContact CB-CB 4.14Å; F608-W859 AromaticContact CE2-CD1 3.31Å; F608-W859 HydrophobicContact CE2-CG 4.25Å; F608-W859 AromaticContact CE2-NE1 3.72Å; F814-W859 HydrophobicContact CD1-CZ2 4.2Å; F814-W859 HydrophobicContact CD2-CZ2 4.28Å; F814-W859 AromaticContact CE1-CH2 3.95Å; F814-W859 HydrophobicContact CE1-CH2 3.95Å; F814-W859 AromaticContact CE1-CZ2 3.7Å; F814-W859 HydrophobicContact CE1-CZ2 3.7Å; F814-W859 AromaticContact CE2-CH2 3.81Å; F814-W859 HydrophobicContact CE2-CH2 3.81Å; F814-W859 AromaticContact CE2-CZ2 3.79Å; F814-W859 HydrophobicContact CE2-CZ2 3.79Å; F814-W859 HydrophobicContact CG-CZ2 4.48Å; F814-W859 AromaticContact CZ-CH2 3.36Å; F814-W859 HydrophobicContact CZ-CH2 3.36Å; F814-W859 AromaticContact CZ-CZ2 3.47Å; F814-W859 HydrophobicContact CZ-CZ2 3.47Å; F814-W859 VanDerWaalsContact CZ-CZ2 3.47Å; F814-W859 PolarHBondContact O-NE1 3.43Å; Y817-W859 AromaticContact CD1-CH2 3.85Å; Y817-W859 HydrophobicContact CD1-CH2 3.85Å; Y817-W859 AromaticContact CD1-CZ2 3.85Å; Y817-W859 HydrophobicContact CD1-CZ2 3.85Å; Y817-W859 HydrophobicContact CD1-CZ3 4.44Å; Y817-W859 HydrophobicContact CE1-CH2 4.46Å; Y817-W859 HydrophobicContact CG-CZ2 4.4Å; N853-W859 HydrophobicContact CB-CE3 4.14Å; N853-W859 HydrophobicContact CB-CZ3 3.7Å; N853-W859 WeakPolarHBondContact ND2-CH2 3.49Å; N853-W859 WeakPolarHBondContact ND2-CZ3 3.5Å; W855-W859 HydrophobicContact CB-CB 4.35Å; W855-W859 AromaticContact CE3-CD1 3.89Å; W855-W859 AromaticContact CE3-CD2 3.58Å; W855-W859 HydrophobicContact CE3-CD2 3.58Å; W855-W859 AromaticContact CE3-CE2 3.53Å; W855-W859 HydrophobicContact CE3-CE3 4.15Å; W855-W859 AromaticContact CE3-CG 3.81Å; W855-W859 HydrophobicContact CE3-CG 3.81Å; W855-W859 HydrophobicContact CE3-CZ2 4.05Å; W855-W859 AromaticContact CE3-NE1 3.72Å; W855-W859 HydrophobicContact CZ3-CD2 4.15Å; W855-W859 AromaticContact CZ3-CE2 3.58Å; W855-W859 HydrophobicContact CZ3-CG 4.5Å; W855-W859 AromaticContact CZ3-CZ2 3.82Å; W855-W859 HydrophobicContact CZ3-CZ2 3.82Å; W855-W859 AromaticContact CZ3-NE1 3.64Å; N857-W859 VanDerWaalsContact C-N 3.33Å; W859-G863 VanDerWaalsContact O-CA 3.24Å; W859-G863 WeakPolarHBondContact O-CA 3.46Å; W859-G863 PolarHBondContact O-N 3.35Å; W859-L865 HydrophobicContact CH2-CB 4.07Å; W859-L865 HydrophobicContact CH2-CD1 4.31Å; W859-L865 HydrophobicContact CZ3-CB 4.23Å
860G91.6Very high84.2Confident11 Ų1139.2 Ų39.211%0.11319%0.189CC..THydrogen-bonded Turntrans59.1-149.9177.500000113.7N605 K818 N862N605-G860 PolarHBondContact OD1-N 2.86Å; K818-G860 CarbonylContact O-C 3.51Å; G860-N862 VanDerWaalsContact C-N 3.28Å; G860-N862 PolarHBondContact O-N 3.44Å
861E89.8Confident81.7Confident58 Ų5839.1 Ų39.127%0.27119%0.19SC..BIsolated β-bridgetrans-81.172.1178.7-61.2-170.3164.700110.5K818 S819 G820 G863 K864 Q866K818-E861 PolarHBondContact O-N 3.13Å; S819-E861 VanDerWaalsContact CA-OE1 3.28Å; S819-E861 WeakPolarHBondContact CA-OE1 3.48Å; S819-E861 VanDerWaalsContact CB-OE1 3.27Å; S819-E861 WeakPolarHBondContact CB-OE1 3.09Å; G820-E861 PolarHBondContact N-OE1 3.48Å; E861-G863 VanDerWaalsContact C-N 3.3Å; E861-G863 PolarHBondContact O-N 3.35Å; E861-K864 HydrophobicContact CB-CB 4.32Å; E861-K864 PolarHBondContact N-O 3.3Å; E861-K864 WeakPolarHBondContact O-CB 3.36Å; E861-K864 PolarHBondContact O-N 3.13Å; E861-Q866 PolarHBondContact OE2-NE2 2.88Å
862N89.3Confident79.2Confident94 Ų9443.6 Ų43.650%0.50321%0.213SC..THydrogen-bonded Turntrans55.247.1-174.7-167.925.2000111.3N857 G860N857-N862 WeakPolarHBondContact CB-OD1 3.4Å; G860-N862 VanDerWaalsContact C-N 3.28Å; G860-N862 PolarHBondContact O-N 3.44Å
863G86Confident77Confident0 Ų043.6 Ų43.60%021%0.212CC..THydrogen-bonded Turntrans86.6-0.9-178.800000115.9N853 G856 W859 E861N853-G863 WeakPolarHBondContact CB-O 3.27Å; N853-G863 PolarHBondContact N-O 3.26Å; N853-G863 VanDerWaalsContact N-O 3.1Å; G856-G863 VanDerWaalsContact O-CA 3.27Å; G856-G863 WeakPolarHBondContact O-CA 3.46Å; W859-G863 VanDerWaalsContact O-CA 3.24Å; W859-G863 WeakPolarHBondContact O-CA 3.46Å; W859-G863 PolarHBondContact O-N 3.35Å; E861-G863 VanDerWaalsContact C-N 3.3Å; E861-G863 PolarHBondContact O-N 3.35Å
864K89.7Confident74.8Confident45 Ų4543.6 Ų43.620%0.19621%0.213CC..EExtended strand (participates in β ladder)trans-104.9157.8-178.5-56.6166-162.1170.10111.4R652 I665 V851 E861R652-K864 VanDerWaalsContact NH1-CE 3.32Å; I665-K864 HydrophobicContact CD1-CG 3.93Å; V851-K864 CarbonylContact O-C 3.54Å; V851-K864 VanDerWaalsContact O-CA 3.3Å; V851-K864 WeakPolarHBondContact O-CA 3.37Å; E861-K864 HydrophobicContact CB-CB 4.32Å; E861-K864 PolarHBondContact N-O 3.3Å; E861-K864 WeakPolarHBondContact O-CB 3.36Å; E861-K864 PolarHBondContact O-N 3.13Å
865L86.8Confident72.2Confident0 Ų043.3 Ų43.30%021%0.211CC..EExtended strand (participates in β ladder)trans-135.9136.8179.5167.875.2000109.2F814 Y817 Y822 V851 W859F814-L865 HydrophobicContact CE2-CD1 3.84Å; F814-L865 HydrophobicContact CE2-CD2 3.58Å; F814-L865 HydrophobicContact CE2-CG 4.32Å; F814-L865 HydrophobicContact CZ-CD2 3.77Å; Y817-L865 HydrophobicContact CD1-CD1 3.78Å; Y817-L865 HydrophobicContact CD2-CD1 4.12Å; Y817-L865 HydrophobicContact CE1-CB 4.26Å; Y817-L865 HydrophobicContact CE1-CD1 3.55Å; Y817-L865 HydrophobicContact CE2-CD1 3.9Å; Y817-L865 HydrophobicContact CG-CD1 4.05Å; Y822-L865 VanDerWaalsContact CB-CD1 3.49Å; Y822-L865 HydrophobicContact CG-CD1 4.19Å; V851-L865 HydrophobicContact CB-CB 4.12Å; V851-L865 HydrophobicContact CB-CD2 4.3Å; V851-L865 HydrophobicContact CB-CG 4.49Å; V851-L865 HydrophobicContact CG1-CD2 4.48Å; V851-L865 HydrophobicContact CG2-CD2 4.5Å; V851-L865 PolarHBondContact N-O 2.78Å; V851-L865 PolarHBondContact O-N 2.99Å; W859-L865 HydrophobicContact CH2-CB 4.07Å; W859-L865 HydrophobicContact CH2-CD1 4.31Å; W859-L865 HydrophobicContact CZ3-CB 4.23Å
866Q79.7Confident69.9Low32 Ų3243.3 Ų43.315%0.1521%0.211CC..EExtended strand (participates in β ladder)trans-103.8125.1161.5-57.5172.925.100107.2Y817 V821 Y822 Y848 W849 L850 E861Y817-Q866 PolarHBondContact OH-N 2.91Å; V821-Q866 CarbonylContact C-O 3.44Å; V821-Q866 WeakPolarHBondContact CA-O 3.49Å; V821-Q866 HydrophobicContact CG2-CB 4.27Å; Y822-Q866 PolarHBondContact N-O 3.49Å; Y848-Q866 HydrophobicContact CD2-CB 3.64Å; Y848-Q866 HydrophobicContact CD2-CG 3.79Å; Y848-Q866 HydrophobicContact CE2-CB 4.24Å; Y848-Q866 HydrophobicContact CE2-CG 3.86Å; Y848-Q866 HydrophobicContact CG-CB 3.96Å; Y848-Q866 HydrophobicContact CG-CG 4.47Å; W849-Q866 VanDerWaalsContact O-CA 3.31Å; W849-Q866 WeakPolarHBondContact O-CA 3.48Å; L850-Q866 HydrophobicContact CD1-CG 4.34Å; E861-Q866 PolarHBondContact OE2-NE2 2.88Å
867S72.9Confident67Low2 Ų245.3 Ų45.31%0.01422%0.22CC..EExtended strand (participates in β ladder)trans-155.3150.7-175.4-176.10000114.2Y822 W849 L869Y822-S867 PolarHBondContact O-OG 3.39Å; W849-S867 PolarHBondContact N-O 3.34Å; W849-S867 PolarHBondContact O-N 3.26Å; W849-S867 VanDerWaalsContact O-N 3.1Å; S867-L869 PolarHBondContact O-N 3.48Å
868F58.9Low64Low102 Ų10241.4 Ų41.445%0.44720%0.2SC..  trans-76.6106.4159.3-70.4-90.8000109.3V821 V823 E846 K847V821-F868 HydrophobicContact CG1-CD2 3.8Å; V821-F868 HydrophobicContact CG1-CE2 3.79Å; V823-F868 HydrophobicContact CG2-CD2 3.71Å; V823-F868 HydrophobicContact CG2-CE2 4.12Å; E846-F868 HydrophobicContact CB-CE2 3.99Å; E846-F868 HydrophobicContact CB-CZ 3.8Å; E846-F868 HydrophobicContact CG-CE2 4.41Å; E846-F868 HydrophobicContact CG-CZ 4.27Å; K847-F868 HydrophobicContact CB-CE1 4.34Å; K847-F868 WeakPolarHBondContact O-CD1 3.43Å; K847-F868 WeakPolarHBondContact O-CE1 3.46Å; K847-F868 VanDerWaalsContact O-CE2 3.27Å; K847-F868 WeakPolarHBondContact O-CE2 3.18Å; K847-F868 WeakPolarHBondContact O-CZ 3.35Å
869L52.7Low60.9Low18 Ų1842.1 Ų42.19%0.09421%0.206CC..  trans-104.9121.9175.6-64.9176.5000109.4A806 F808 V835 I837 W849 V851 S867A806-L869 HydrophobicContact CB-CD1 4.49Å; F808-L869 HydrophobicContact CB-CD2 3.79Å; F808-L869 HydrophobicContact CD1-CD2 4.16Å; F808-L869 HydrophobicContact CD2-CD2 3.69Å; F808-L869 HydrophobicContact CE2-CD2 4.32Å; F808-L869 HydrophobicContact CG-CD2 3.61Å; V835-L869 HydrophobicContact CG2-CD1 4.39Å; I837-L869 HydrophobicContact CD1-CD1 3.99Å; I837-L869 HydrophobicContact CG1-CD1 4.35Å; W849-L869 HydrophobicContact CB-CD1 4.48Å; W849-L869 PolarHBondContact NE1-O 3.33Å; V851-L869 HydrophobicContact CG2-CD1 3.84Å; S867-L869 PolarHBondContact O-N 3.48Å
870Q41.1Very low57.7Low201 Ų20144.1 Ų44.194%0.93922%0.219SC*.  trans-100.8105.7163.9-151.4138.62800105.7
871S41.9Very low54.6Low18 Ų1849.2 Ų49.213%0.12625%0.247CC..  trans-144.2158.4-159.253.50000114.2I807 I873I807-S871 WeakPolarHBondContact O-CB 3.09Å; S871-I873 WeakPolarHBondContact OG-CD1 3.46Å; S871-I873 WeakPolarHBondContact OG-CG1 3.28Å
872L39.9Very low51.5Low93 Ų9350.8 Ų50.849%0.48727%0.265SS..EExtended strand (participates in β ladder)trans-90.8129.3164.2-165.584000108.2I807I807-L872 PolarHBondContact N-O 2.82Å
873I48.3Very low48.4Very low4 Ų456.5 Ų56.52%0.02129%0.285CS..EExtended strand (participates in β ladder)trans-128.5132.1-169.4-67.3168.5000110.4I787 I794 V804 I805 A806 I837 S871 T875I787-I873 HydrophobicContact CB-CB 4.23Å; I787-I873 HydrophobicContact CB-CG2 4.02Å; I787-I873 HydrophobicContact CD1-CG2 3.6Å; I787-I873 HydrophobicContact CG1-CG2 4Å; I787-I873 PolarHBondContact N-O 2.99Å; I794-I873 HydrophobicContact CB-CD1 4.18Å; I794-I873 HydrophobicContact CD1-CD1 3.13Å; I794-I873 HydrophobicContact CG1-CD1 3.3Å; I794-I873 HydrophobicContact CG2-CD1 3.8Å; V804-I873 HydrophobicContact CB-CG2 4.15Å; V804-I873 HydrophobicContact CG2-CG2 4.14Å; I805-I873 WeakPolarHBondContact O-CA 3.46Å; I805-I873 WeakPolarHBondContact O-CG2 3.35Å; A806-I873 HydrophobicContact CB-CD1 4.35Å; A806-I873 HydrophobicContact CB-CG1 3.85Å; I837-I873 HydrophobicContact CD1-CD1 4.44Å; S871-I873 WeakPolarHBondContact OG-CD1 3.46Å; S871-I873 WeakPolarHBondContact OG-CG1 3.28Å; I873-T875 HydrophobicContact CG2-CG2 4Å
874C48.2Very low45.5Very low6 Ų661.2 Ų61.24%0.04132%0.319CS..EExtended strand (participates in β ladder)trans-122.4129.8-178.4-61.20000110.1L724 I805L724-C874 HydrophobicContact CD1-CB 3.83Å; I805-C874 PolarHBondContact O-N 2.97Å
875T40.2Very low42.3Very low0 Ų066.7 Ų66.70%034%0.342CS..EExtended strand (participates in β ladder)trans-149.3-178.5-174.767.90000115.5Y785 I787 V804 I873Y785-T875 WeakPolarHBondContact CE2-OG1 3.38Å; Y785-T875 PolarHBondContact N-O 2.88Å; Y785-T875 CarbonylContact O-C 3.55Å; Y785-T875 PolarHBondContact O-N 2.9Å; I787-T875 HydrophobicContact CD1-CG2 3.33Å; I787-T875 WeakPolarHBondContact CD1-OG1 3.18Å; I787-T875 HydrophobicContact CG1-CG2 3.88Å; I787-T875 WeakPolarHBondContact CG1-OG1 3.45Å; V804-T875 HydrophobicContact CB-CG2 3.31Å; V804-T875 HydrophobicContact CG1-CG2 3.31Å; I873-T875 HydrophobicContact CG2-CG2 4Å
876L46.5Very low39.4Very low1 Ų174.6 Ų74.61%0.00538%0.379CS..EExtended strand (participates in β ladder)trans-142.6149-152.1-70.3147.1000114.4V682 M683 R686 L724 W727 A781 R783 V784 Y785V682-L876 HydrophobicContact CG1-CD1 4.2Å; M683-L876 HydrophobicContact CG-CD1 4.31Å; R686-L876 VanDerWaalsContact NH1-N 3.19Å; R686-L876 PolarHBondContact NH1-O 2.94Å; L724-L876 HydrophobicContact CB-CD2 4.38Å; L724-L876 HydrophobicContact CD1-CD1 4.42Å; L724-L876 HydrophobicContact CD1-CD2 4.46Å; L724-L876 HydrophobicContact CD1-CG 4.22Å; L724-L876 HydrophobicContact CD2-CD1 3.39Å; L724-L876 HydrophobicContact CD2-CD2 4.06Å; L724-L876 HydrophobicContact CD2-CG 3.92Å; L724-L876 HydrophobicContact CG-CD1 4.47Å; W727-L876 HydrophobicContact CE3-CD1 3.67Å; W727-L876 HydrophobicContact CE3-CD2 3.44Å; W727-L876 VanDerWaalsContact CE3-CD2 3.44Å; W727-L876 HydrophobicContact CE3-CG 4.09Å; W727-L876 HydrophobicContact CH2-CD1 4.35Å; W727-L876 HydrophobicContact CZ3-CB 4.12Å; W727-L876 HydrophobicContact CZ3-CD1 3.23Å; W727-L876 HydrophobicContact CZ3-CD2 3.42Å; W727-L876 VanDerWaalsContact CZ3-CD2 3.42Å; W727-L876 HydrophobicContact CZ3-CG 3.71Å; A781-L876 HydrophobicContact CB-CD2 4.06Å; R783-L876 WeakPolarHBondContact O-CD2 3.04Å; V784-L876 HydrophobicContact CB-CD2 4.24Å; V784-L876 HydrophobicContact CG2-CD2 3.58Å; Y785-L876 VanDerWaalsContact CE1-C 3.46Å; Y785-L876 PolarHBondContact OH-O 3.29Å
877D29.4Very low36.8Very low48 Ų4881 Ų8126%0.25741%0.414SS..EExtended strand (participates in β ladder)trans-116.1132160.9-1627.3000109.5R783 Y785R783-D877 HydrophobicContact CB-CB 4.34Å; R783-D877 PolarHBondContact N-O 3.33Å; R783-D877 PolarHBondContact O-N 2.88Å; Y785-D877 HydrophobicContact CE1-CB 4.1Å
878V29.3Very low34.5Very low6 Ų689.3 Ų89.34%0.03645%0.453CS..  trans-112.6129.6-169.8-169.60000108.9R686 L690 W727 V880R686-V878 HydrophobicContact CB-CG2 3.89Å; L690-V878 WeakPolarHBondContact CD1-O 3.39Å; L690-V878 HydrophobicContact CD2-CB 3.96Å; L690-V878 HydrophobicContact CD2-CG1 3.81Å; L690-V878 WeakPolarHBondContact CD2-O 3.44Å; L690-V878 WeakPolarHBondContact CG-O 2.98Å; W727-V878 HydrophobicContact CH2-CG1 4.3Å; W727-V878 HydrophobicContact CH2-CG2 3.57Å; W727-V878 HydrophobicContact CZ3-CG2 4.17Å; V878-V880 HydrophobicContact CG1-CG2 4.06Å
879K24.2Very low32.8Very low145 Ų14590.9 Ų90.963%0.6347%0.471SS*.  trans-126.7114.6156.9-164.4174.3-176.9178.50107.9Q782 T881Q782-K879 HydrophobicContact CB-CB 4.48Å; K879-T881 PolarHBondContact O-N 2.9Å
880V25.1Very low31.5Very low43 Ų4398.2 Ų98.226%0.26151%0.511SS..  trans-77.3105.5-178.8177.70000108.8T687 L690 T691 V878 S882T687-V880 HydrophobicContact CG2-CG2 4.03Å; L690-V880 HydrophobicContact CD2-CB 4.47Å; L690-V880 HydrophobicContact CD2-CG2 3.92Å; T691-V880 HydrophobicContact CG2-CB 4.41Å; T691-V880 HydrophobicContact CG2-CG2 3.92Å; V878-V880 HydrophobicContact CG1-CG2 4.06Å; V880-S882 PolarHBondContact O-N 2.92Å
881T26.1Very low30.7Very low117 Ų11793 Ų9372%0.71850%0.501SS*.  trans-81.594.8162.349.80000108.4K879 K883K879-T881 PolarHBondContact O-N 2.9Å; T881-K883 PolarHBondContact O-N 3.35Å
882S25.4Very low30Very low92 Ų92101.1 Ų101.164%0.64354%0.537SS*.  trans-72.5110.3164.4540000108.1V880 S884V880-S882 PolarHBondContact O-N 2.92Å; S882-S884 PolarHBondContact O-N 3.3Å
883K24.5Very low29.4Very low213 Ų213104 Ų10493%0.92655%0.552SS**  trans-71.676.1162.3-78.4-172.5174.7-173.80108.3T881T881-K883 PolarHBondContact O-N 3.35Å
884S24.7Very low28.2Very low100 Ų100111.1 Ų111.170%0.69959%0.591SS**  trans-75.3136155.647.40000107.6S882S882-S884 PolarHBondContact O-N 3.3Å
885K23.6Very low27.1Very low159 Ų159117 Ų11769%0.69162%0.622SS**  trans-51.4149.8-178.3-71.3173.1158.6-165.60112.6D887K885-D887 PolarHBondContact O-N 2.68Å
886E25.2Very low26.4Very low166 Ų166124.1 Ų124.178%0.77666%0.658SS**  trans35.883.2140.6-66.3160.8157.600115.2
887D24.4Very low25.2Very low166 Ų166134.1 Ų134.189%0.88870%0.696SS**  trans-123.5108.5141.4-83.6-40.6000106.3K885K885-D887 PolarHBondContact O-N 2.68Å
888E24.7Very low25Very low178 Ų178137.8 Ų137.883%0.83272%0.72SS**  trans-61162.1165.5-70.7179.7137.800110.4
889T24.2Very low24.7Very low135 Ų135142.6 Ų142.683%0.82875%0.751SS**SBendtrans82.1102.1168.955.10000118.6A891T889-A891 PolarHBondContact O-N 3.44Å
890N25Very low24.9Very low172 Ų172143.1 Ų143.192%0.9276%0.756SS**  trans11.6106.1138.5-73.2-23.8000116.8
891A24.5Very low24.9Very low90 Ų90148.2 Ų148.274%0.74478%0.781SS**  trans-144.697.4147.600000109.2T889 L893T889-A891 PolarHBondContact O-N 3.44Å; A891-L893 PolarHBondContact O-N 2.02Å
892E25.9Very low24.8Very low189 Ų189150.6 Ų150.688%0.88379%0.785SS**  trans29.689.3140.7-61-177.715500117.9
893L27.5Very low24.6Very low153 Ų153156.3 Ų156.380%0.80179%0.792SS**  trans-134.443154.1-87170000111.5A891A891-L893 PolarHBondContact O-N 2.02Å
894N23.6Very low24.5Very low155 Ų155154.8 Ų154.883%0.82979%0.786SS**  trans-88.485.9142.8-82.5-23000106.7
895N24.8Very low24.2Very low129 Ų129157.5 Ų157.569%0.6979%0.785SS**  trans179.141.9158.3-96.1-21.8000115.4R897N895-R897 PolarHBondContact O-N 3.48Å
896I26.9Very low24.1Very low149 Ų149159.4 Ų159.476%0.76479%0.794SS**  trans-90.780.3153.6-58.8178.8000107.2V898I896-V898 PolarHBondContact O-N 3.49Å; I896-V898 VanDerWaalsContact O-N 3.12Å
897R21.1Very low23.9Very low212 Ų212156.6 Ų156.680%0.878%0.784SS**  trans-57.6104.7159.4-77.5177.8175.2176.9-3.1107.4N895N895-R897 PolarHBondContact O-N 3.48Å
898V24.8Very low23.8Very low124 Ų124154.9 Ų154.975%0.75279%0.785SS**  trans-73.3120.9154.6-178.20000105.4I896 E900I896-V898 PolarHBondContact O-N 3.49Å; I896-V898 VanDerWaalsContact O-N 3.12Å; V898-E900 PolarHBondContact O-N 2.58Å
899P23.3Very low23.6Very low107 Ų107149.8 Ų149.870%0.69577%0.773SS**  trans-56131.5-173.6-23.131.7000111.9N901P899-N901 PolarHBondContact O-N 3.38Å
900E28.2Very low23.6Very low157 Ų157150.7 Ų150.773%0.73477%0.771SS**SBendtrans-71.214-172.6-135.7172.8179.800114.9V898V898-E900 PolarHBondContact O-N 2.58Å
901N24.9Very low23.5Very low149 Ų149150.9 Ų150.980%0.79777%0.771SS**  trans-12132.9-165.1-67.8-8.9000115.7P899P899-N901 PolarHBondContact O-N 3.38Å
902Q23.8Very low23.5Very low168 Ų168151.9 Ų151.979%0.78577%0.768SS**  trans-128.458.2157.3-71.8-168.1-8.100110.9F904Q902-F904 PolarHBondContact O-N 2.79Å
903R21.4Very low23.3Very low211 Ų211150.5 Ų150.580%0.79677%0.767SS**  trans-73.6110.7154-70.5-176.2179.4-173.61.8107K905R903-K905 PolarHBondContact O-N 2.72Å; R903-K905 VanDerWaalsContact O-N 3.11Å
904F21.6Very low22.9Very low182 Ų182150 Ų15080%0.79877%0.765SS**  trans-61.2114.9163.1-77.2-87.6000107.8Q902 F906Q902-F904 PolarHBondContact O-N 2.79Å; F904-F906 PolarHBondContact O-N 2.03Å
905K19.2Very low22.7Very low156 Ų156148.1 Ų148.168%0.67876%0.763SS**  trans-71.4109.6-178.1-163.8-174.2-173-123.30107.9R903 D907R903-K905 PolarHBondContact O-N 2.72Å; R903-K905 VanDerWaalsContact O-N 3.11Å; K905-D907 WeakPolarHBondContact CE-OD1 3.43Å; K905-D907 IonicContact NZ-OD1 3.76Å; K905-D907 PolarHBondContact NZ-OD1 3.43Å; K905-D907 IonicContact NZ-OD2 2.91Å; K905-D907 PolarHBondContact NZ-OD2 2.89Å
906F21.3Very low22.5Very low200 Ų200146.6 Ų146.688%0.87775%0.754SS**  trans-96.6110.1147.7-80.4-82.7000106F904 S908F904-F906 PolarHBondContact O-N 2.03Å; F906-S908 PolarHBondContact O-N 2.82Å; F906-S908 VanDerWaalsContact O-N 3.13Å
907D21.4Very low22.2Very low107 Ų107147.5 Ų147.557%0.57276%0.761SS**  trans-54.8113.1-179.9-102.7-52000110.3K905 A909K905-D907 WeakPolarHBondContact CE-OD1 3.43Å; K905-D907 IonicContact NZ-OD1 3.76Å; K905-D907 PolarHBondContact NZ-OD1 3.43Å; K905-D907 IonicContact NZ-OD2 2.91Å; K905-D907 PolarHBondContact NZ-OD2 2.89Å; D907-A909 HydrophobicContact CB-CB 4.48Å; D907-A909 PolarHBondContact O-N 2.94Å; D907-A909 VanDerWaalsContact O-N 3.13Å
908S21.6Very low22.2Very low130 Ų130143.9 Ų143.991%0.90976%0.757SS**  trans-76.683.2154.5179.50000107.1F906F906-S908 PolarHBondContact O-N 2.82Å; F906-S908 VanDerWaalsContact O-N 3.13Å
909A21.3Very low22.1Very low70 Ų70142.1 Ų142.158%0.57975%0.75SS**  trans-15856.6174.900000112.4D907D907-A909 HydrophobicContact CB-CB 4.48Å; D907-A909 PolarHBondContact O-N 2.94Å; D907-A909 VanDerWaalsContact O-N 3.13Å
910I23.8Very low22Very low154 Ų154145 Ų14579%0.7976%0.756SS**  trans-135.782.4143.9-56.4-176.5000107.7T912I910-T912 VanDerWaalsContact CG2-OG1 3.24Å; I910-T912 WeakPolarHBondContact CG2-OG1 3.25Å
911L23.5Very low21.9Very low177 Ų177143.1 Ų143.193%0.92776%0.755SS**  trans-77.6109.5145.1-87.8164.3000106.4
912T22.8Very low21.9Very low110 Ų110143.1 Ų143.168%0.67576%0.755SS**  trans-149116.2153.35.30000109.8I910 L914I910-T912 VanDerWaalsContact CG2-OG1 3.24Å; I910-T912 WeakPolarHBondContact CG2-OG1 3.25Å; T912-L914 PolarHBondContact O-N 3.19Å
913N21.6Very low21.9Very low160 Ų160142.6 Ų142.686%0.85676%0.757SS**  trans-2799.7160.8-67.7-36.9000112.5
914L20.2Very low22.4Very low144 Ų144135.8 Ų135.875%0.75475%0.752SS**  trans-10793151.5-118111.2000107.1T912 L916T912-L914 PolarHBondContact O-N 3.19Å; L914-L916 HydrophobicContact CD2-CD1 3.7Å; L914-L916 HydrophobicContact CD2-CG 4Å; L914-L916 PolarHBondContact O-N 2.87Å
915S20.2Very low23Very low114 Ų114132.9 Ų132.980%0.79774%0.743SS**  trans-56.883.3161.2-42.30000108.6
916L20.1Very low24.1Very low97 Ų97128 Ų12851%0.50872%0.724SS.*  trans-98.296.1165.6-86.4160.9000107.7L914 L918L914-L916 HydrophobicContact CD2-CD1 3.7Å; L914-L916 HydrophobicContact CD2-CG 4Å; L914-L916 PolarHBondContact O-N 2.87Å; L916-L918 PolarHBondContact O-N 3.37Å
917N21Very low25.4Very low169 Ų169123.9 Ų123.990%0.90471%0.711SS**  trans-53.486.5151.4-82.8-25.3000108.2
918L21.2Very low26.7Very low135 Ų135124.2 Ų124.271%0.70771%0.709SS**  trans-101.4104.9161-85.8160.9000106.3L916 M920L916-L918 PolarHBondContact O-N 3.37Å; L918-M920 PolarHBondContact O-N 3.42Å; L918-M920 VanDerWaalsContact O-N 3.11Å
919S22.3Very low28.1Very low88 Ų88120.3 Ų120.362%0.61568%0.676SS**  trans-44.3116.9164.453.80000109.1T921S919-T921 PolarHBondContact O-N 3.45Å
920M21.6Very low29.5Very low167 Ų167124 Ų12482%0.82368%0.675SS**G310 helixtrans-6310.1176.2-83.7-178.237.900114.4L918 N922L918-M920 PolarHBondContact O-N 3.42Å; L918-M920 VanDerWaalsContact O-N 3.11Å; M920-N922 VanDerWaalsContact C-N 3.33Å; M920-N922 PolarHBondContact O-N 2.95Å
921T24.7Very low30.8Very low117 Ų117120.4 Ų120.472%0.71868%0.676SS**G310 helixtrans-79.3-6.9-172.7400000115S919S919-T921 PolarHBondContact O-N 3.45Å
922N24.5Very low32.2Very low149 Ų149114.3 Ų114.380%0.79764%0.644SS**G310 helixtrans-116.916.1-179.2-77.97.5000115.6M920 G924M920-N922 VanDerWaalsContact C-N 3.33Å; M920-N922 PolarHBondContact O-N 2.95Å; N922-G924 PolarHBondContact O-N 3.34Å
923L25.7Very low33.8Very low158 Ų158111.6 Ų111.683%0.82763%0.629SS**  trans-76.473.5164-73.8171.3000109.1M925L923-M925 PolarHBondContact O-N 2.8Å
924G31.8Very low35.3Very low67 Ų67109.4 Ų109.469%0.69162%0.617SS**  trans-66.3118.9169.600000109.4N922 N926N922-G924 PolarHBondContact O-N 3.34Å; G924-N926 PolarHBondContact O-N 3.47Å
925M32.6Very low36.9Very low122 Ų122108.3 Ų108.360%0.60161%0.612SS**  trans-75.6111.6169-140.3174.277.100107.6L923 D927 R930L923-M925 PolarHBondContact O-N 2.8Å; M925-D927 PolarHBondContact O-N 2.64Å; M925-R930 HydrophobicContact CE-CB 4.15Å; M925-R930 HydrophobicContact CE-CG 3.8Å; M925-R930 PolarHBondContact O-NH2 3.13Å; M925-R930 VanDerWaalsContact O-NH2 3.11Å
926N42.9Very low38.5Very low54 Ų54106.9 Ų106.929%0.28960%0.595SS.*  trans-56.7132.1-179.5-172.9-48.1000110.4G924 H928 F929 R930G924-N926 PolarHBondContact O-N 3.47Å; N926-H928 PolarHBondContact O-N 2.9Å; N926-H928 VanDerWaalsContact OD1-CB 3.25Å; N926-H928 WeakPolarHBondContact OD1-CB 3.42Å; N926-H928 PolarHBondContact OD1-N 2.82Å; N926-F929 HydrophobicContact CB-CD2 4.28Å; N926-F929 PolarHBondContact O-N 2.77Å; N926-R930 PolarHBondContact O-N 3.47Å
927D47.8Very low39.9Very low113 Ų113103.7 Ų103.760%0.60458%0.578SS**G310 helixtrans-58.7-29.7-178.1-77.5-36.9000112.9M925 F929 R930M925-D927 PolarHBondContact O-N 2.64Å; D927-F929 VanDerWaalsContact C-N 3.27Å; D927-F929 PolarHBondContact O-N 2.88Å; D927-R930 WeakPolarHBondContact O-CB 3.44Å; D927-R930 PolarHBondContact O-N 2.87Å; D927-R930 VanDerWaalsContact O-N 3.16Å; D927-R930 IonicContact OD1-CZ 3.49Å; D927-R930 IonicContact OD1-NE 3.32Å; D927-R930 PolarHBondContact OD1-NE 3.46Å; D927-R930 IonicContact OD1-NH1 3.4Å; D927-R930 PolarHBondContact OD1-NH1 2.81Å; D927-R930 IonicContact OD1-NH2 3.95Å
928H49.2Very low41.3Very low114 Ų11497.7 Ų97.753%0.52855%0.546SS..G310 helixtrans-59.3-36.8179.1-170.879.4000112.8N926N926-H928 PolarHBondContact O-N 2.9Å; N926-H928 VanDerWaalsContact OD1-CB 3.25Å; N926-H928 WeakPolarHBondContact OD1-CB 3.42Å; N926-H928 PolarHBondContact OD1-N 2.82Å
929F52.3Low42.8Very low47 Ų4795 Ų9521%0.20654%0.543CS..G310 helixtrans-99.7-1.7179.8-55.6-70000112.9N926 D927 G931 M932 I937 W1035N926-F929 HydrophobicContact CB-CD2 4.28Å; N926-F929 PolarHBondContact O-N 2.77Å; D927-F929 VanDerWaalsContact C-N 3.27Å; D927-F929 PolarHBondContact O-N 2.88Å; F929-G931 PolarHBondContact O-N 3.48Å; F929-G931 VanDerWaalsContact O-N 3.11Å; F929-M932 HydrophobicContact CD1-CE 4.26Å; F929-M932 HydrophobicContact CD1-SD 4.03Å; F929-M932 PolarHBondContact O-N 3.05Å; F929-I937 HydrophobicContact CD1-CG1 4.25Å; F929-W1035 HydrophobicContact CZ-CH2 4.33Å; F929-W1035 HydrophobicContact CZ-CZ3 4.43Å
930R49.3Very low44.2Very low147 Ų14795.9 Ų95.956%0.55554%0.541SS*.THydrogen-bonded Turntrans-69.9111.3-175.8-173.9177.3-76.9173.1-3.4109.6M925 N926 D927M925-R930 HydrophobicContact CE-CB 4.15Å; M925-R930 HydrophobicContact CE-CG 3.8Å; M925-R930 PolarHBondContact O-NH2 3.13Å; M925-R930 VanDerWaalsContact O-NH2 3.11Å; N926-R930 PolarHBondContact O-N 3.47Å; D927-R930 WeakPolarHBondContact O-CB 3.44Å; D927-R930 PolarHBondContact O-N 2.87Å; D927-R930 VanDerWaalsContact O-N 3.16Å; D927-R930 IonicContact OD1-CZ 3.49Å; D927-R930 IonicContact OD1-NE 3.32Å; D927-R930 PolarHBondContact OD1-NE 3.46Å; D927-R930 IonicContact OD1-NH1 3.4Å; D927-R930 PolarHBondContact OD1-NH1 2.81Å; D927-R930 IonicContact OD1-NH2 3.95Å
931G52Low45.3Very low80 Ų8089.4 Ų89.483%0.82551%0.508SS*.THydrogen-bonded Turntrans95.40.3179.600000115F929F929-G931 PolarHBondContact O-N 3.48Å; F929-G931 VanDerWaalsContact O-N 3.11Å
932M52.1Low46.2Very low49 Ų4986.3 Ų86.324%0.24150%0.495CS..  trans-78.5145.5170.8-73.817552.600111.6F929 D936 I937 L940F929-M932 HydrophobicContact CD1-CE 4.26Å; F929-M932 HydrophobicContact CD1-SD 4.03Å; F929-M932 PolarHBondContact O-N 3.05Å; M932-D936 HydrophobicContact CB-CB 4.23Å; M932-D936 HydrophobicContact CE-CB 3.77Å; M932-D936 HydrophobicContact CG-CB 4.49Å; M932-I937 HydrophobicContact CB-CG1 4.07Å; M932-I937 HydrophobicContact CE-CB 4.29Å; M932-I937 HydrophobicContact CE-CG1 3.62Å; M932-L940 HydrophobicContact CE-CD1 3.26Å; M932-L940 HydrophobicContact SD-CD1 4.05Å
933S56.7Low46.8Very low52 Ų5280.8 Ų80.836%0.36447%0.47SS..  trans-75.1160.2169.273.60000110.9D935 D936 I937S933-D935 PolarHBondContact O-N 3Å; S933-D936 WeakPolarHBondContact CB-OD2 3.33Å; S933-D936 PolarHBondContact N-OD2 2.98Å; S933-D936 PolarHBondContact O-N 3.05Å; S933-D936 VanDerWaalsContact O-N 3.14Å; S933-D936 PolarHBondContact OG-N 3.46Å; S933-D936 PolarHBondContact OG-OD2 3.45Å; S933-I937 WeakPolarHBondContact O-CG1 3.28Å; S933-I937 PolarHBondContact O-N 2.89Å
934L53.8Low47.2Very low114 Ų11484.4 Ų84.460%0.59747%0.473SS*.Hα-helixtrans-58.5-33.4175-167.376.4000111.4I937 N938L934-I937 PolarHBondContact O-N 3.39Å; L934-N938 WeakPolarHBondContact O-CB 3.3Å; L934-N938 PolarHBondContact O-N 2.86Å; L934-N938 PolarHBondContact O-ND2 2.68Å
935D52.2Low47.1Very low121 Ų12186.2 Ų86.265%0.64747%0.466SS*.Hα-helixtrans-68.9-38.3178-64.2-28000111.6S933 I937 N938 A939S933-D935 PolarHBondContact O-N 3Å; D935-I937 VanDerWaalsContact C-N 3.35Å; D935-N938 PolarHBondContact O-N 3.47Å; D935-A939 WeakPolarHBondContact O-CB 3.36Å; D935-A939 PolarHBondContact O-N 2.83Å
936D55.2Low47.1Very low84 Ų8486.8 Ų86.845%0.44947%0.472SS..Hα-helixtrans-66.1-39.3174-59.2-49.3000111.3M932 S933 A939 L940M932-D936 HydrophobicContact CB-CB 4.23Å; M932-D936 HydrophobicContact CE-CB 3.77Å; M932-D936 HydrophobicContact CG-CB 4.49Å; S933-D936 WeakPolarHBondContact CB-OD2 3.33Å; S933-D936 PolarHBondContact N-OD2 2.98Å; S933-D936 PolarHBondContact O-N 3.05Å; S933-D936 VanDerWaalsContact O-N 3.14Å; S933-D936 PolarHBondContact OG-N 3.46Å; S933-D936 PolarHBondContact OG-OD2 3.45Å; D936-A939 PolarHBondContact O-N 3.45Å; D936-L940 WeakPolarHBondContact O-CB 3.37Å; D936-L940 PolarHBondContact O-N 2.9Å
937I50.1Low46.5Very low31 Ų3191.3 Ų91.316%0.15949%0.491CS..Hα-helixtrans-63.9-45.1174.7-63.5172.1000110F929 M932 S933 L934 D935 A939 L940 M941 I1010F929-I937 HydrophobicContact CD1-CG1 4.25Å; M932-I937 HydrophobicContact CB-CG1 4.07Å; M932-I937 HydrophobicContact CE-CB 4.29Å; M932-I937 HydrophobicContact CE-CG1 3.62Å; S933-I937 WeakPolarHBondContact O-CG1 3.28Å; S933-I937 PolarHBondContact O-N 2.89Å; L934-I937 PolarHBondContact O-N 3.39Å; D935-I937 VanDerWaalsContact C-N 3.35Å; I937-A939 VanDerWaalsContact C-N 3.34Å; I937-A939 PolarHBondContact O-N 2.98Å; I937-L940 PolarHBondContact O-N 2.67Å; I937-M941 HydrophobicContact CG2-CE 4.47Å; I937-M941 HydrophobicContact CG2-CG 4.11Å; I937-M941 VanDerWaalsContact O-CB 3.3Å; I937-M941 WeakPolarHBondContact O-CB 3.29Å; I937-M941 VanDerWaalsContact O-CG 3.22Å; I937-M941 WeakPolarHBondContact O-CG 3.31Å; I937-M941 PolarHBondContact O-N 3.44Å; I937-I1010 HydrophobicContact CG2-CG2 4.2Å
938N49.4Very low45.7Very low43 Ų4388 Ų8823%0.2348%0.479CS..Hα-helixtrans-61.6-41.8176.7-71.7-23.6000111.6L934 D935 L940 M941 A942 I1010 E1011L934-N938 WeakPolarHBondContact O-CB 3.3Å; L934-N938 PolarHBondContact O-N 2.86Å; L934-N938 PolarHBondContact O-ND2 2.68Å; D935-N938 PolarHBondContact O-N 3.47Å; N938-L940 PolarHBondContact O-N 3.01Å; N938-M941 PolarHBondContact O-N 3.02Å; N938-A942 VanDerWaalsContact O-CB 3.24Å; N938-A942 WeakPolarHBondContact O-CB 3.47Å; N938-A942 PolarHBondContact O-N 3.34Å; N938-I1010 WeakPolarHBondContact OD1-CG2 3.42Å; N938-E1011 HydrophobicContact CB-CG 4.45Å
939A52.5Low45.1Very low77 Ų7788.2 Ų88.264%0.63648%0.48SS*.Hα-helixtrans-64-39177.200000112.5D935 D936 I937D935-A939 WeakPolarHBondContact O-CB 3.36Å; D935-A939 PolarHBondContact O-N 2.83Å; D936-A939 PolarHBondContact O-N 3.45Å; I937-A939 VanDerWaalsContact C-N 3.34Å; I937-A939 PolarHBondContact O-N 2.98Å
940L50.9Low44.1Very low108 Ų10892 Ų9257%0.56550%0.502SS*.Hα-helixtrans-70.6-36.7175.6-100.1149000113M932 D936 I937 N938M932-L940 HydrophobicContact CE-CD1 3.26Å; M932-L940 HydrophobicContact SD-CD1 4.05Å; D936-L940 WeakPolarHBondContact O-CB 3.37Å; D936-L940 PolarHBondContact O-N 2.9Å; I937-L940 PolarHBondContact O-N 2.67Å; N938-L940 PolarHBondContact O-N 3.01Å
941M46.5Very low43.2Very low30 Ų3090.4 Ų90.415%0.14850%0.499CS..Hα-helixtrans-88.6-8-176.5-66.6-118.8-73.800113.6I937 N938 A943 I1010 E1011 T1012 W1035I937-M941 HydrophobicContact CG2-CE 4.47Å; I937-M941 HydrophobicContact CG2-CG 4.11Å; I937-M941 VanDerWaalsContact O-CB 3.3Å; I937-M941 WeakPolarHBondContact O-CB 3.29Å; I937-M941 VanDerWaalsContact O-CG 3.22Å; I937-M941 WeakPolarHBondContact O-CG 3.31Å; I937-M941 PolarHBondContact O-N 3.44Å; N938-M941 PolarHBondContact O-N 3.02Å; M941-A943 PolarHBondContact O-N 3.2Å; M941-I1010 HydrophobicContact CE-CB 3.85Å; M941-I1010 HydrophobicContact CE-CG2 3.82Å; M941-E1011 HydrophobicContact CB-CB 3.77Å; M941-T1012 CarbonylContact O-C 3.49Å; M941-W1035 HydrophobicContact SD-CH2 4.09Å; M941-W1035 HydrophobicContact SD-CZ2 3.97Å
942A41.8Very low42.1Very low52 Ų5290.5 Ų90.543%0.4348%0.481SS..  trans-7388.3-178.400000111.4N938 R944N938-A942 VanDerWaalsContact O-CB 3.24Å; N938-A942 WeakPolarHBondContact O-CB 3.47Å; N938-A942 PolarHBondContact O-N 3.34Å; A942-R944 PolarHBondContact O-N 3.43Å
943A37Very low41.1Very low34 Ų3491 Ų9128%0.28149%0.49SS..  trans-66.7117.2156.800000108.1M941 L945 T1012M941-A943 PolarHBondContact O-N 3.2Å; A943-L945 VanDerWaalsContact C-N 3.32Å; A943-L945 PolarHBondContact O-N 3.04Å; A943-T1012 WeakPolarHBondContact CB-O 3.5Å; A943-T1012 PolarHBondContact N-O 3.36Å
944R34.4Very low39.9Very low233 Ų23391.8 Ų91.888%0.87949%0.492SS*.  trans-63.798164.2-73.7-173.9-178.7177.52.9107.7A942 D946A942-R944 PolarHBondContact O-N 3.43Å; R944-D946 PolarHBondContact O-N 2.95Å
945L30.7Very low38.7Very low106 Ų10690.1 Ų90.156%0.55548%0.482SS*.THydrogen-bonded Turntrans-71.658.2176.4-76161.8000111.4A943 H947 A948 T1012A943-L945 VanDerWaalsContact C-N 3.32Å; A943-L945 PolarHBondContact O-N 3.04Å; L945-H947 VanDerWaalsContact C-N 3.33Å; L945-A948 HydrophobicContact CD2-CB 4.33Å; L945-T1012 HydrophobicContact CD1-CG2 3.9Å; L945-T1012 HydrophobicContact CD2-CG2 4.2Å; L945-T1012 HydrophobicContact CG-CG2 4.35Å
946D32.1Very low37.9Very low134 Ų13488.9 Ų88.972%0.71748%0.476SS*.THydrogen-bonded Turntrans-87.8-10.3153.8-103.7-20.3000110.6R944R944-D946 PolarHBondContact O-N 2.95Å
947H31.5Very low36.8Very low148 Ų14890.2 Ų90.269%0.68548%0.481SS*.THydrogen-bonded Turntrans-94.5-0.9-176.8-83.4-143.5000115.1L945 E949 L950 F951L945-H947 VanDerWaalsContact C-N 3.33Å; H947-E949 PolarHBondContact O-N 3.22Å; H947-E949 VanDerWaalsContact O-N 3.14Å; H947-L950 PolarHBondContact O-N 3.48Å; H947-L950 VanDerWaalsContact O-N 3.15Å; H947-F951 PolarHBondContact O-N 3.14Å
948A30.2Very low35.9Very low44 Ų4492.6 Ų92.636%0.36449%0.494SS..Hα-helixtrans-57.9-25.5171.400000111.8L945 F951 N952L945-A948 HydrophobicContact CD2-CB 4.33Å; A948-F951 PolarHBondContact O-N 2.79Å; A948-N952 PolarHBondContact O-N 2.78Å
949E36.7Very low35.2Very low119 Ų11995.7 Ų95.756%0.55651%0.51SS*.Hα-helixtrans-66.8-36.6176.9-69.4-168.2148.100113.6H947 F951 S953H947-E949 PolarHBondContact O-N 3.22Å; H947-E949 VanDerWaalsContact O-N 3.14Å; E949-F951 VanDerWaalsContact C-N 3.32Å; E949-S953 WeakPolarHBondContact O-CB 3.07Å; E949-S953 PolarHBondContact O-N 2.92Å; E949-S953 PolarHBondContact O-OG 3.03Å
950L30.3Very low34.3Very low125 Ų12599 Ų9965%0.65452%0.517SS*.Hα-helixtrans-70.8-34.3175.3-145.488.8000110.5H947 T954H947-L950 PolarHBondContact O-N 3.48Å; H947-L950 VanDerWaalsContact O-N 3.15Å; L950-T954 WeakPolarHBondContact O-CB 3.44Å; L950-T954 PolarHBondContact O-N 3.46Å; L950-T954 PolarHBondContact O-OG1 3.04Å
951F30.9Very low33.4Very low114 Ų11499.7 Ų99.750%0.552%0.516SS..Hα-helixtrans-67.5-43.6177.9-158.3-96.2000111.7H947 A948 E949 T954 M955 I1017H947-F951 PolarHBondContact O-N 3.14Å; A948-F951 PolarHBondContact O-N 2.79Å; E949-F951 VanDerWaalsContact C-N 3.32Å; F951-T954 PolarHBondContact O-N 3.48Å; F951-M955 HydrophobicContact CD1-CG 4.38Å; F951-M955 HydrophobicContact CE1-CE 3.83Å; F951-M955 HydrophobicContact CE1-CG 4.3Å; F951-M955 HydrophobicContact CZ-CE 3.94Å; F951-M955 PolarHBondContact O-N 2.87Å; F951-I1017 HydrophobicContact CZ-CD1 4.45Å
952N30.2Very low33Very low83 Ų83104 Ų10444%0.44454%0.544SS..Hα-helixtrans-71.6-37176.7-76-3.8000112.9A948 T954 M955 D956A948-N952 PolarHBondContact O-N 2.78Å; N952-T954 PolarHBondContact O-N 3.48Å; N952-M955 PolarHBondContact O-N 2.64Å; N952-M955 VanDerWaalsContact O-N 3.13Å; N952-D956 PolarHBondContact O-N 3.5Å
953S31.1Very low33Very low60 Ų60110.6 Ų110.642%0.4257%0.566SS.*Hα-helixtrans-62.9-32.7173.2-50.30000111.9E949 I957E949-S953 WeakPolarHBondContact O-CB 3.07Å; E949-S953 PolarHBondContact O-N 2.92Å; E949-S953 PolarHBondContact O-OG 3.03Å; S953-I957 WeakPolarHBondContact O-CD1 3.26Å; S953-I957 WeakPolarHBondContact O-CG1 3.45Å; S953-I957 PolarHBondContact O-N 3.07Å
954T30.3Very low33.1Very low67 Ų67111.3 Ų111.341%0.41157%0.572SS.*Hα-helixtrans-75.6-33.1175.3-50.90000111.1L950 F951 N952 I957 L958L950-T954 WeakPolarHBondContact O-CB 3.44Å; L950-T954 PolarHBondContact O-N 3.46Å; L950-T954 PolarHBondContact O-OG1 3.04Å; F951-T954 PolarHBondContact O-N 3.48Å; N952-T954 PolarHBondContact O-N 3.48Å; T954-I957 PolarHBondContact O-N 3.09Å; T954-L958 HydrophobicContact CG2-CD1 4.4Å; T954-L958 VanDerWaalsContact O-CG 3.28Å; T954-L958 WeakPolarHBondContact O-CG 3.34Å; T954-L958 PolarHBondContact O-N 2.89Å; T954-L958 VanDerWaalsContact O-N 3.12Å
955M29.7Very low33.9Very low79 Ų79110.4 Ų110.439%0.38957%0.574SS.*Hα-helixtrans-71.5-36.3173.2-76.8-64.9175.400113F951 N952 I957 L958 D959F951-M955 HydrophobicContact CD1-CG 4.38Å; F951-M955 HydrophobicContact CE1-CE 3.83Å; F951-M955 HydrophobicContact CE1-CG 4.3Å; F951-M955 HydrophobicContact CZ-CE 3.94Å; F951-M955 PolarHBondContact O-N 2.87Å; N952-M955 PolarHBondContact O-N 2.64Å; N952-M955 VanDerWaalsContact O-N 3.13Å; M955-I957 PolarHBondContact O-N 2.66Å; M955-L958 HydrophobicContact CE-CD1 4.26Å; M955-L958 CarbonylContact O-C 3.52Å; M955-L958 WeakPolarHBondContact O-CA 3.32Å; M955-L958 PolarHBondContact O-N 2.91Å; M955-L958 HydrophobicContact SD-CB 4.31Å; M955-L958 HydrophobicContact SD-CD1 3.77Å; M955-D959 PolarHBondContact O-N 2.84Å
956D33.4Very low35.1Very low96 Ų96110.6 Ų110.651%0.51358%0.575SS.*Hα-helixtrans-61.6-32.2171.6-73.7-20.7000111R788 N952 L958R788-D956 IonicContact NH2-OD2 3.12Å; N952-D956 PolarHBondContact O-N 3.5Å; D956-L958 VanDerWaalsContact C-N 3.32Å
957I34.1Very low36.7Very low111 Ų111107.4 Ų107.457%0.56956%0.562SS**Hα-helixtrans-74-22.9171.8-66.5167.5000111.9S953 T954 M955 F961S953-I957 WeakPolarHBondContact O-CD1 3.26Å; S953-I957 WeakPolarHBondContact O-CG1 3.45Å; S953-I957 PolarHBondContact O-N 3.07Å; T954-I957 PolarHBondContact O-N 3.09Å; M955-I957 PolarHBondContact O-N 2.66Å; I957-F961 WeakPolarHBondContact O-CD2 3.24Å
958L30.2Very low38.5Very low81 Ų81107.9 Ų107.942%0.42456%0.564SS.*Hα-helixtrans-90.2-26.7-179.9-72166.4000113.4T954 M955 D956 D960 F961T954-L958 HydrophobicContact CG2-CD1 4.4Å; T954-L958 VanDerWaalsContact O-CG 3.28Å; T954-L958 WeakPolarHBondContact O-CG 3.34Å; T954-L958 PolarHBondContact O-N 2.89Å; T954-L958 VanDerWaalsContact O-N 3.12Å; M955-L958 HydrophobicContact CE-CD1 4.26Å; M955-L958 CarbonylContact O-C 3.52Å; M955-L958 WeakPolarHBondContact O-CA 3.32Å; M955-L958 PolarHBondContact O-N 2.91Å; M955-L958 HydrophobicContact SD-CB 4.31Å; M955-L958 HydrophobicContact SD-CD1 3.77Å; D956-L958 VanDerWaalsContact C-N 3.32Å; L958-D960 PolarHBondContact O-N 3.2Å; L958-F961 HydrophobicContact CD2-CD2 4.28Å; L958-F961 WeakPolarHBondContact O-CA 3.4Å; L958-F961 WeakPolarHBondContact O-CB 3.02Å; L958-F961 PolarHBondContact O-N 3.47Å
959D33.8Very low40.4Very low108 Ų108111.7 Ų111.758%0.57857%0.573SS**Hα-helixtrans-64.8-26.3173.2-88.3-9.5000112.1M955 F961 T962M955-D959 PolarHBondContact O-N 2.84Å; D959-F961 PolarHBondContact O-N 2.73Å; D959-F961 VanDerWaalsContact O-N 3.16Å; D959-T962 WeakPolarHBondContact O-CB 3.36Å; D959-T962 WeakPolarHBondContact O-CG2 3.17Å; D959-T962 PolarHBondContact O-N 3.39Å; D959-T962 VanDerWaalsContact O-N 3.16Å; D959-T962 PolarHBondContact O-OG1 3.16Å
960D34.5Very low42Very low146 Ų146108.5 Ų108.578%0.78156%0.557SS**THydrogen-bonded Turntrans-64.6-11.3168.6-87.9-7.7000113.2L958L958-D960 PolarHBondContact O-N 3.2Å
961F32.2Very low43.7Very low124 Ų124103.4 Ų103.454%0.54453%0.53SS..THydrogen-bonded Turntrans-92.27.7174-76-88.4000114.2I957 L958 D959 E963 A964I957-F961 WeakPolarHBondContact O-CD2 3.24Å; L958-F961 HydrophobicContact CD2-CD2 4.28Å; L958-F961 WeakPolarHBondContact O-CA 3.4Å; L958-F961 WeakPolarHBondContact O-CB 3.02Å; L958-F961 PolarHBondContact O-N 3.47Å; D959-F961 PolarHBondContact O-N 2.73Å; D959-F961 VanDerWaalsContact O-N 3.16Å; F961-E963 PolarHBondContact O-N 3.05Å; F961-A964 WeakPolarHBondContact O-CB 3.22Å; F961-A964 PolarHBondContact O-N 3.35Å
962T39Very low44.9Very low119 Ų119100.1 Ų100.173%0.7352%0.524SS*.THydrogen-bonded Turntrans-61.8-12.1-178.341.50000115.1D959D959-T962 WeakPolarHBondContact O-CB 3.36Å; D959-T962 WeakPolarHBondContact O-CG2 3.17Å; D959-T962 PolarHBondContact O-N 3.39Å; D959-T962 VanDerWaalsContact O-N 3.16Å; D959-T962 PolarHBondContact O-OG1 3.16Å
963E39.9Very low46Very low192 Ų192101.8 Ų101.890%0.89752%0.524SS*.THydrogen-bonded Turntrans-87.9-9.5170.8-69.7-167.8166.100114.7F961 K965F961-E963 PolarHBondContact O-N 3.05Å; E963-K965 PolarHBondContact O-N 3.2Å
964A40.5Very low47Very low48 Ų48104.1 Ų104.140%0.39753%0.529SS..SBendtrans-77.8119.6177.700000110.5F961 L966F961-A964 WeakPolarHBondContact O-CB 3.22Å; F961-A964 PolarHBondContact O-N 3.35Å; A964-L966 HydrophobicContact CB-CD2 4.33Å; A964-L966 HydrophobicContact CB-CG 4.47Å; A964-L966 PolarHBondContact O-N 3.31Å
965K50Low48Very low215 Ų215107.2 Ų107.294%0.93554%0.536SS*.  trans-62.986.6163.2-77.7-175.4178.2179.10109.2E963E963-K965 PolarHBondContact O-N 3.2Å
966L56.4Low48.7Very low110 Ų110110.6 Ų110.658%0.57655%0.545SS*.  trans-71143173.9-65.5175.4000109.8A964 W1020A964-L966 HydrophobicContact CB-CD2 4.33Å; A964-L966 HydrophobicContact CB-CG 4.47Å; A964-L966 PolarHBondContact O-N 3.31Å; L966-W1020 HydrophobicContact CB-CZ2 4.16Å; L966-W1020 HydrophobicContact CD1-CZ2 4.32Å; L966-W1020 HydrophobicContact CD2-CH2 4.4Å; L966-W1020 HydrophobicContact CD2-CZ2 4.18Å; L966-W1020 HydrophobicContact CG-CZ2 4.46Å
967P65.1Low49Very low66 Ų66113.5 Ų113.543%0.42955%0.553SS.*  trans-67.4146.9177.629.3-35.2000111.1K969 F970 W1020P967-K969 WeakPolarHBondContact CB-O 3.39Å; P967-K969 PolarHBondContact O-N 3.2Å; P967-K969 VanDerWaalsContact O-N 3.12Å; P967-F970 HydrophobicContact CG-CB 4.07Å; P967-F970 HydrophobicContact CG-CD2 4.21Å; P967-W1020 PolarHBondContact O-NE1 2.76Å
968E70.2Confident49.2Very low158 Ų158114.4 Ų114.474%0.73856%0.555SS**SBendtrans-58.2-25.7178.9-76.4-165.3142.800113.2G1021 K1022E968-G1021 WeakPolarHBondContact O-CA 3.48Å; E968-K1022 PolarHBondContact O-N 2.77Å
969K70.5Confident49.3Very low124 Ų124119.9 Ų119.954%0.53957%0.57SS.*SBendtrans-133.8130.6171.6-175.1-179.1176.9-172.80108.5P967P967-K969 WeakPolarHBondContact CB-O 3.39Å; P967-K969 PolarHBondContact O-N 3.2Å; P967-K969 VanDerWaalsContact O-N 3.12Å
970F70.1Confident49Very low53 Ų53117.8 Ų117.823%0.23257%0.568CS.*EExtended strand (participates in β ladder)trans-133129.3175.5178.3-102.3000109.8P967 A972 K975 G1019 W1020P967-F970 HydrophobicContact CG-CB 4.07Å; P967-F970 HydrophobicContact CG-CD2 4.21Å; F970-A972 HydrophobicContact CE1-CB 3.94Å; F970-A972 HydrophobicContact CZ-CB 4.25Å; F970-K975 HydrophobicContact CE2-CG 4.14Å; F970-G1019 CarbonylContact O-C 3.37Å; F970-G1019 WeakPolarHBondContact O-CA 3.35Å; F970-W1020 HydrophobicContact CB-CD2 3.57Å; F970-W1020 HydrophobicContact CB-CE3 3.91Å; F970-W1020 HydrophobicContact CB-CG 4.23Å; F970-W1020 HydrophobicContact CB-CH2 3.61Å; F970-W1020 HydrophobicContact CB-CZ2 3.23Å; F970-W1020 HydrophobicContact CB-CZ3 3.94Å; F970-W1020 HydrophobicContact CD1-CD2 4.17Å; F970-W1020 AromaticContact CD1-CE3 3.59Å; F970-W1020 HydrophobicContact CD1-CE3 3.59Å; F970-W1020 AromaticContact CD1-CH2 3.28Å; F970-W1020 HydrophobicContact CD1-CH2 3.28Å; F970-W1020 AromaticContact CD1-CZ2 3.9Å; F970-W1020 HydrophobicContact CD1-CZ2 3.9Å; F970-W1020 AromaticContact CD1-CZ3 3.11Å; F970-W1020 HydrophobicContact CD1-CZ3 3.11Å; F970-W1020 HydrophobicContact CD2-CH2 4.1Å; F970-W1020 HydrophobicContact CD2-CZ2 4.26Å; F970-W1020 HydrophobicContact CE1-CE3 4.48Å; F970-W1020 AromaticContact CE1-CH2 3.88Å; F970-W1020 HydrophobicContact CE1-CH2 3.88Å; F970-W1020 AromaticContact CE1-CZ3 3.7Å; F970-W1020 HydrophobicContact CE1-CZ3 3.7Å; F970-W1020 HydrophobicContact CG-CD2 4.27Å; F970-W1020 AromaticContact CG-CE2 3.98Å; F970-W1020 HydrophobicContact CG-CE3 4.12Å; F970-W1020 AromaticContact CG-CH2 3.39Å; F970-W1020 HydrophobicContact CG-CH2 3.39Å; F970-W1020 AromaticContact CG-CZ2 3.55Å; F970-W1020 HydrophobicContact CG-CZ2 3.55Å; F970-W1020 AromaticContact CG-CZ3 3.71Å; F970-W1020 HydrophobicContact CG-CZ3 3.71Å; F970-W1020 PolarHBondContact N-O 3.48Å; F970-W1020 PolarHBondContact O-N 3.3Å; F970-W1020 VanDerWaalsContact O-O 3.07Å
971D64.5Low48.8Very low17 Ų17115.7 Ų115.79%0.09156%0.564CS.*EExtended strand (participates in β ladder)trans-126.8113.1171.3-170.8-22.5000108.3R973 E974 L1030D971-R973 VanDerWaalsContact CG-NE 3.29Å; D971-R973 PolarHBondContact O-N 3.04Å; D971-R973 WeakPolarHBondContact OD1-CB 3.09Å; D971-R973 WeakPolarHBondContact OD1-CG 3.3Å; D971-R973 IonicContact OD1-CZ 3.08Å; D971-R973 PolarHBondContact OD1-N 3.34Å; D971-R973 IonicContact OD1-NE 3.61Å; D971-R973 PolarHBondContact OD1-NE 2.99Å; D971-R973 IonicContact OD1-NH2 3.45Å; D971-R973 IonicContact OD2-CZ 3.06Å; D971-R973 VanDerWaalsContact OD2-CZ 3.23Å; D971-R973 IonicContact OD2-NE 2.69Å; D971-R973 PolarHBondContact OD2-NE 3.35Å; D971-R973 IonicContact OD2-NH2 2.57Å; D971-R973 PolarHBondContact OD2-NH2 2.99Å; D971-E974 HydrophobicContact CB-CB 4.38Å; D971-E974 HydrophobicContact CB-CG 4.04Å; D971-E974 PolarHBondContact O-N 2.88Å; D971-L1030 HydrophobicContact CB-CD1 4.33Å
972A56.3Low48.5Very low45 Ų45116.9 Ų116.937%0.37258%0.575SS.*Hα-helixtrans-57.4-20.617900000112.3F970 R976 V1018F970-A972 HydrophobicContact CE1-CB 3.94Å; F970-A972 HydrophobicContact CZ-CB 4.25Å; A972-R976 PolarHBondContact O-N 3.31Å; A972-V1018 VanDerWaalsContact CB-O 3.32Å; A972-V1018 WeakPolarHBondContact CB-O 3.4Å; A972-V1018 PolarHBondContact N-O 3.11Å
973R53.3Low47.9Very low118 Ų118116.3 Ų116.345%0.44557%0.567SS.*Hα-helixtrans-75.5-32.6178.1-53.5169.7-68.9-170.22112.3D971 R976 K977D971-R973 VanDerWaalsContact CG-NE 3.29Å; D971-R973 PolarHBondContact O-N 3.04Å; D971-R973 WeakPolarHBondContact OD1-CB 3.09Å; D971-R973 WeakPolarHBondContact OD1-CG 3.3Å; D971-R973 IonicContact OD1-CZ 3.08Å; D971-R973 PolarHBondContact OD1-N 3.34Å; D971-R973 IonicContact OD1-NE 3.61Å; D971-R973 PolarHBondContact OD1-NE 2.99Å; D971-R973 IonicContact OD1-NH2 3.45Å; D971-R973 IonicContact OD2-CZ 3.06Å; D971-R973 VanDerWaalsContact OD2-CZ 3.23Å; D971-R973 IonicContact OD2-NE 2.69Å; D971-R973 PolarHBondContact OD2-NE 3.35Å; D971-R973 IonicContact OD2-NH2 2.57Å; D971-R973 PolarHBondContact OD2-NH2 2.99Å; R973-R976 WeakPolarHBondContact O-CB 3.39Å; R973-R976 PolarHBondContact O-N 3.22Å; R973-K977 PolarHBondContact O-N 3.29Å
974E53.4Low47.1Very low110 Ų110113.2 Ų113.251%0.51457%0.566SS.*Hα-helixtrans-70.5-44.5177.3-72.1-176.717000111.4D971 R976 K977 E978D971-E974 HydrophobicContact CB-CB 4.38Å; D971-E974 HydrophobicContact CB-CG 4.04Å; D971-E974 PolarHBondContact O-N 2.88Å; E974-R976 PolarHBondContact O-N 2.97Å; E974-K977 WeakPolarHBondContact O-CB 3.2Å; E974-K977 PolarHBondContact O-N 2.83Å; E974-E978 PolarHBondContact O-N 2.64Å
975K50.7Low46.4Very low131 Ų131115.4 Ų115.457%0.5758%0.575SS**Hα-helixtrans-57.7-31171.5-85.9-115.6176.5-178.50112.9F970 R979F970-K975 HydrophobicContact CE2-CG 4.14Å; K975-R979 PolarHBondContact O-N 3.47Å
976R43.9Very low45.2Very low150 Ų150110.4 Ų110.457%0.56656%0.562SS**Hα-helixtrans-70.5-33.2176.1-149.9170.7-172.3153.3-3.9111.9A972 R973 E974 A980 Y993A972-R976 PolarHBondContact O-N 3.31Å; R973-R976 WeakPolarHBondContact O-CB 3.39Å; R973-R976 PolarHBondContact O-N 3.22Å; E974-R976 PolarHBondContact O-N 2.97Å; R976-A980 WeakPolarHBondContact O-CB 3.38Å; R976-A980 PolarHBondContact O-N 3.13Å; R976-Y993 WeakPolarHBondContact CD-OH 3.35Å; R976-Y993 PolarHBondContact NE-OH 3.37Å; R976-Y993 VanDerWaalsContact NE-OH 3.08Å
977K40.4Very low43.8Very low158 Ų158115.1 Ų115.169%0.68757%0.574SS**Hα-helixtrans-68.4-40.9173.2-69.9-179.1179177.10112.4R973 E974 A980 S981R973-K977 PolarHBondContact O-N 3.29Å; E974-K977 WeakPolarHBondContact O-CB 3.2Å; E974-K977 PolarHBondContact O-N 2.83Å; K977-A980 WeakPolarHBondContact O-CB 3.38Å; K977-A980 PolarHBondContact O-N 3.27Å; K977-S981 PolarHBondContact O-N 2.76Å
978E38.6Very low42.1Very low129 Ų129116.5 Ų116.560%0.60359%0.585SS**Hα-helixtrans-59.5-46.9173.4-86.8-174.5151.900111.7E974 A980 S981 L982E974-E978 PolarHBondContact O-N 2.64Å; E978-A980 VanDerWaalsContact C-N 3.3Å; E978-A980 PolarHBondContact O-N 3.48Å; E978-S981 PolarHBondContact O-N 3.48Å; E978-S981 PolarHBondContact O-OG 2.76Å; E978-L982 PolarHBondContact O-N 2.94Å
979R31.4Very low40.1Very low197 Ų197114.6 Ų114.674%0.74358%0.58SS**Hα-helixtrans-62.8-34.2174.6-92.6-175.7170.1178.8-2.5113.2K975 S981K975-R979 PolarHBondContact O-N 3.47Å; R979-S981 VanDerWaalsContact C-N 3.33Å
980A28.6Very low38.1Very low64 Ų64113.8 Ų113.853%0.52958%0.581SS.*Hα-helixtrans-69.1-31.117600000112.2R976 K977 E978 L982 I983R976-A980 WeakPolarHBondContact O-CB 3.38Å; R976-A980 PolarHBondContact O-N 3.13Å; K977-A980 WeakPolarHBondContact O-CB 3.38Å; K977-A980 PolarHBondContact O-N 3.27Å; E978-A980 VanDerWaalsContact C-N 3.3Å; E978-A980 PolarHBondContact O-N 3.48Å; A980-L982 VanDerWaalsContact C-N 3.33Å; A980-L982 PolarHBondContact O-N 3.18Å; A980-I983 PolarHBondContact O-N 3Å
981S29.5Very low35.9Very low101 Ų101118.1 Ų118.171%0.70661%0.612SS**Hα-helixtrans-71.2-24.6178.472.40000114.2K977 E978 R979 I983K977-S981 PolarHBondContact O-N 2.76Å; E978-S981 PolarHBondContact O-N 3.48Å; E978-S981 PolarHBondContact O-OG 2.76Å; R979-S981 VanDerWaalsContact C-N 3.33Å; S981-I983 VanDerWaalsContact C-N 3.29Å; S981-I983 PolarHBondContact O-N 3.24Å
982L26.1Very low34.2Very low149 Ų149126.1 Ų126.178%0.7864%0.642SS**THydrogen-bonded Turntrans-80.8-6.6177.2-86.1159.5000113.8E978 A980E978-L982 PolarHBondContact O-N 2.94Å; A980-L982 VanDerWaalsContact C-N 3.33Å; A980-L982 PolarHBondContact O-N 3.18Å
983I25.6Very low32.6Very low108 Ų108131.4 Ų131.455%0.55465%0.654SS**  trans-123.491.3-169.5-61.1177.3000108A980 S981 V985A980-I983 PolarHBondContact O-N 3Å; S981-I983 VanDerWaalsContact C-N 3.29Å; S981-I983 PolarHBondContact O-N 3.24Å; I983-V985 VanDerWaalsContact C-N 3.29Å; I983-V985 HydrophobicContact CG2-CB 3.94Å; I983-V985 HydrophobicContact CG2-CG2 3.33Å; I983-V985 PolarHBondContact O-N 2.75Å
984S24.1Very low31.1Very low126 Ų126135.2 Ų135.288%0.88167%0.673SS**  trans-69.987.3163.760.80000108.6
985V26.8Very low29.9Very low95 Ų95139.2 Ų139.258%0.57668%0.684SS**  trans-128.2142.2172.3-178.40000110I983I983-V985 VanDerWaalsContact C-N 3.29Å; I983-V985 HydrophobicContact CG2-CB 3.94Å; I983-V985 HydrophobicContact CG2-CG2 3.33Å; I983-V985 PolarHBondContact O-N 2.75Å
986T24Very low28.5Very low110 Ų110139.6 Ų139.668%0.67569%0.691SS**  trans-62.6159.5-164.841.30000115.2S988T986-S988 PolarHBondContact O-N 3.4Å
987Y27.7Very low27.7Very low208 Ų208138 Ų13882%0.81670%0.698SS**THydrogen-bonded Turntrans-6113.2-163-142.7-98000117.9L990Y987-L990 HydrophobicContact CD1-CD1 3.84Å; Y987-L990 HydrophobicContact CD2-CD1 3.32Å; Y987-L990 HydrophobicContact CE1-CD1 3.79Å; Y987-L990 HydrophobicContact CE2-CD1 3.26Å; Y987-L990 HydrophobicContact CG-CD1 3.61Å
988S27.6Very low26.8Very low96 Ų96135.4 Ų135.467%0.67170%0.695SS**THydrogen-bonded Turntrans-87.3-12.4175.448.20000114.1T986T986-S988 PolarHBondContact O-N 3.4Å
989D28.9Very low26.4Very low117 Ų117135.3 Ų135.363%0.62670%0.698SS**SBendtrans-92.911.5-179.2-72.4-31000114.5T991D989-T991 PolarHBondContact O-N 2.93Å
990L27.7Very low26.1Very low108 Ų108128.3 Ų128.357%0.56569%0.688SS**THydrogen-bonded Turntrans-90.310.5-168-88.5164.2000116.9Y987Y987-L990 HydrophobicContact CD1-CD1 3.84Å; Y987-L990 HydrophobicContact CD2-CD1 3.32Å; Y987-L990 HydrophobicContact CE1-CD1 3.79Å; Y987-L990 HydrophobicContact CE2-CD1 3.26Å; Y987-L990 HydrophobicContact CG-CD1 3.61Å
991T24.7Very low26Very low143 Ų143130.9 Ų130.988%0.87769%0.691SS**THydrogen-bonded Turntrans-95.75.2178.6-4.90000115.6D989D989-T991 PolarHBondContact O-N 2.93Å
992Y28.5Very low26.1Very low185 Ų185133.5 Ų133.573%0.72569%0.687SS**SBendtrans-104.4-3.2-176.7-158.1-100.8000116
993Y23.5Very low26.4Very low157 Ų157129.3 Ų129.362%0.61667%0.673SS**  trans-129.578.4-174.4-69.1-80.8000113R976R976-Y993 WeakPolarHBondContact CD-OH 3.35Å; R976-Y993 PolarHBondContact NE-OH 3.37Å; R976-Y993 VanDerWaalsContact NE-OH 3.08Å
994K21.4Very low27.1Very low197 Ų197130.1 Ų130.186%0.85767%0.674SS**  trans-114.5134.3155-82.4-174.4174.41790109.2
995R28.1Very low27.7Very low195 Ų195131.9 Ų131.974%0.73667%0.666SS**  trans124.8130.3146.9-64.2-170.5179.7-176.22.1116.7D1042R995-D1042 IonicContact NH1-OD1 3.31Å
996I21.9Very low28.2Very low139 Ų139134.1 Ų134.171%0.71368%0.68SS**  trans-96.7173.4-169.1-63.8163.8000108.1
997T26.1Very low29.2Very low116 Ų116130.8 Ų130.871%0.71267%0.668SS**  trans99159.2148.3-0.80000119
998T21.9Very low30Very low104 Ų104130.2 Ų130.264%0.63867%0.67SS**  trans-140.3141.5-142.5-39.40000111
999L31.1Very low31Very low126 Ų126133.8 Ų133.866%0.6667%0.673SS**  trans97.1101.6138.3-107.7156.8000121.7E1041L999-E1041 WeakPolarHBondContact CA-OE1 3.4Å; L999-E1041 PolarHBondContact N-OE1 3.08Å; L999-E1041 PolarHBondContact N-OE2 3.44Å
1000G24.1Very low31.9Very low51 Ų51131.9 Ų131.953%0.52666%0.662SS.*  trans-153.1133.314800000113.2E1041G1000-E1041 PolarHBondContact N-OE1 3.05Å; G1000-E1041 PolarHBondContact N-OE2 2.85Å
1001I27.6Very low33.3Very low117 Ų117131.1 Ų131.160%0.666%0.656SS**  trans-100.9125.2177.2-63.3171.1000108.5
1002Y30.1Very low34.5Very low157 Ų157126.2 Ų126.262%0.61663%0.626SS**  trans-111.6117173.1-169.6-95.7000111.4H1004Y1002-H1004 HydrophobicContact CE1-CB 4.34Å
1003A33.4Very low35.9Very low61 Ų61120.2 Ų120.250%0.50460%0.604SS.*  trans-111.2125.7170.400000109.4K1005A1003-K1005 PolarHBondContact O-N 2.88Å
1004H40.8Very low37Very low124 Ų124116.2 Ų116.257%0.57460%0.603SS**  trans-78111-177.3177.8-91.4000111.1Y1002 G1007Y1002-H1004 HydrophobicContact CE1-CB 4.34Å; H1004-G1007 PolarHBondContact CE1-O 3.29Å; H1004-G1007 WeakPolarHBondContact NE2-CA 3.06Å; H1004-G1007 PolarHBondContact NE2-N 3.05Å; H1004-G1007 PolarHBondContact NE2-O 3.49Å; H1004-G1007 VanDerWaalsContact NE2-O 3.16Å
1005K36.3Very low38.7Very low164 Ų164110 Ų11071%0.71358%0.582SS**SBendtrans-107.4-27.4-179.6-76.5-174.5176.2179.60115.9A1003A1003-K1005 PolarHBondContact O-N 2.88Å
1006T37.9Very low39.9Very low142 Ų142109.5 Ų109.587%0.87158%0.58SS**SBendtrans-147.37.6-168.153.90000116.3
1007G43.1Very low41.6Very low40 Ų40107 Ų10741%0.41257%0.567SS.*PPolyproline II helixtrans-84.1152.7-175.900000114.9H1004H1004-G1007 PolarHBondContact CE1-O 3.29Å; H1004-G1007 WeakPolarHBondContact NE2-CA 3.06Å; H1004-G1007 PolarHBondContact NE2-N 3.05Å; H1004-G1007 PolarHBondContact NE2-O 3.49Å; H1004-G1007 VanDerWaalsContact NE2-O 3.16Å
1008K45.6Very low43.3Very low195 Ų195103 Ų10385%0.84854%0.542SS*.PPolyproline II helixtrans-89.4140.9163.4-79.3-175.6177.7179.60108.8I1010K1008-I1010 PolarHBondContact O-N 2.88Å
1009K49.4Very low45.5Very low171 Ų17198.1 Ų98.174%0.74351%0.513SS*.PPolyproline II helixtrans-54.2125.9169-178.7179.3176.8178.90109.1
1010I47.8Very low47.6Very low78 Ų7896.1 Ų96.140%0.450%0.497SS..  trans-96.5-68.4178.2-58.3-179.8000108.5I937 N938 M941 K1008I937-I1010 HydrophobicContact CG2-CG2 4.2Å; N938-I1010 WeakPolarHBondContact OD1-CG2 3.42Å; M941-I1010 HydrophobicContact CE-CB 3.85Å; M941-I1010 HydrophobicContact CE-CG2 3.82Å; K1008-I1010 PolarHBondContact O-N 2.88Å
1011E55.7Low49.8Very low91 Ų9193.9 Ų93.943%0.42547%0.474SS..  trans-154-177.4170.9-88.3-53.4161.700111.5N938 M941N938-E1011 HydrophobicContact CB-CG 4.45Å; M941-E1011 HydrophobicContact CB-CB 3.77Å
1012T50.7Low51.6Low41 Ų4192.8 Ų92.825%0.25247%0.465SS..  trans-105.1130.4180-44.20000111.8M941 A943 L945M941-T1012 CarbonylContact O-C 3.49Å; A943-T1012 WeakPolarHBondContact CB-O 3.5Å; A943-T1012 PolarHBondContact N-O 3.36Å; L945-T1012 HydrophobicContact CD1-CG2 3.9Å; L945-T1012 HydrophobicContact CD2-CG2 4.2Å; L945-T1012 HydrophobicContact CG-CG2 4.35Å
1013H56.5Low53.3Low59 Ų5990.5 Ų90.527%0.27346%0.46SS..  trans-118.7146.2-178.1-174.451.3000112.1D1033 W1035H1013-D1033 IonicContact CD2-OD1 3.39Å; H1013-D1033 PolarHBondContact CD2-OD1 3.45Å; H1013-D1033 IonicContact CD2-OD2 3.58Å; H1013-D1033 PolarHBondContact CD2-OD2 3.4Å; H1013-D1033 IonicContact CE1-OD1 3.66Å; H1013-D1033 IonicContact NE2-OD1 2.74Å; H1013-D1033 PolarHBondContact NE2-OD1 3.35Å; H1013-D1033 IonicContact NE2-OD2 3.63Å; H1013-D1033 PolarHBondContact NE2-OD2 3.47Å; H1013-W1035 AromaticContact CD2-CZ2 3.94Å; H1013-W1035 AromaticContact CE1-NE1 3.62Å; H1013-W1035 AromaticContact NE2-CE2 3.76Å; H1013-W1035 AromaticContact NE2-NE1 3.36Å; H1013-W1035 PolarHBondContact NE2-NE1 2.88Å
1014A48.6Very low54.9Low72 Ų7290.7 Ų90.760%0.59547%0.467SS*.  trans-95.9130.7-178.600000111
1015V56.9Low56.3Low68 Ų6891.7 Ų91.741%0.41248%0.477SS..  trans-134.8158.5-175.4-58.20000111.7V1031 D1033V1015-V1031 HydrophobicContact CB-CG1 3.31Å; V1015-V1031 HydrophobicContact CG1-CG1 4.06Å; V1015-V1031 HydrophobicContact CG2-CG1 3.35Å; V1015-V1031 HydrophobicContact CG2-CG2 4.4Å; V1015-D1033 WeakPolarHBondContact CG1-OD2 3.25Å
1016R52.5Low57.5Low183 Ų18389.3 Ų89.369%0.69147%0.472SS*.EExtended strand (participates in β ladder)trans-97.8121.3179.3-171.2-178.3-174.5-171.95.5111.4V1018 V1031 A1032R1016-V1018 HydrophobicContact CG-CG1 4.19Å; R1016-V1031 CarbonylContact O-C 2.92Å; R1016-V1031 VanDerWaalsContact O-CA 3.3Å; R1016-V1031 WeakPolarHBondContact O-CA 3.49Å; R1016-A1032 HydrophobicContact CB-CB 4.45Å; R1016-A1032 WeakPolarHBondContact CB-O 3.35Å; R1016-A1032 PolarHBondContact N-O 2.76Å; R1016-A1032 PolarHBondContact O-N 3.43Å
1017I57.9Low58.8Low87 Ų8787.5 Ų87.545%0.44645%0.452SS..EExtended strand (participates in β ladder)trans-83.6124.8173-56.4174.7000109.6F951 C1029 L1030 V1031F951-I1017 HydrophobicContact CZ-CD1 4.45Å; I1017-C1029 HydrophobicContact CG2-CB 4.19Å; I1017-L1030 CarbonylContact C-O 3.43Å; I1017-L1030 WeakPolarHBondContact CA-O 3.18Å; I1017-V1031 HydrophobicContact CG1-CG2 4.48Å
1018V62.2Low59.7Low31 Ų3187 Ų8719%0.18844%0.438CS..EExtended strand (participates in β ladder)trans-116.6-1.6-176.2-61.70000113.8A972 R1016 L1030 A1032A972-V1018 VanDerWaalsContact CB-O 3.32Å; A972-V1018 WeakPolarHBondContact CB-O 3.4Å; A972-V1018 PolarHBondContact N-O 3.11Å; R1016-V1018 HydrophobicContact CG-CG1 4.19Å; V1018-L1030 HydrophobicContact CG2-CB 3.83Å; V1018-L1030 PolarHBondContact N-O 3.33Å; V1018-A1032 HydrophobicContact CG1-CB 4.07Å
1019G66.4Low60.4Low2 Ų279.6 Ų79.62%0.02141%0.41CS..EExtended strand (participates in β ladder)trans171.4-172.5176.200000112.5F970 L1030F970-G1019 CarbonylContact O-C 3.37Å; F970-G1019 WeakPolarHBondContact O-CA 3.35Å; G1019-L1030 PolarHBondContact O-N 2.91Å
1020W76.1Confident60.9Low84 Ų8472.2 Ų72.232%0.31838%0.379SS..EExtended strand (participates in β ladder)trans-150.6166.2179.862.786.2000111.4L966 P967 F970 Y1028L966-W1020 HydrophobicContact CB-CZ2 4.16Å; L966-W1020 HydrophobicContact CD1-CZ2 4.32Å; L966-W1020 HydrophobicContact CD2-CH2 4.4Å; L966-W1020 HydrophobicContact CD2-CZ2 4.18Å; L966-W1020 HydrophobicContact CG-CZ2 4.46Å; P967-W1020 PolarHBondContact O-NE1 2.76Å; F970-W1020 HydrophobicContact CB-CD2 3.57Å; F970-W1020 HydrophobicContact CB-CE3 3.91Å; F970-W1020 HydrophobicContact CB-CG 4.23Å; F970-W1020 HydrophobicContact CB-CH2 3.61Å; F970-W1020 HydrophobicContact CB-CZ2 3.23Å; F970-W1020 HydrophobicContact CB-CZ3 3.94Å; F970-W1020 HydrophobicContact CD1-CD2 4.17Å; F970-W1020 AromaticContact CD1-CE3 3.59Å; F970-W1020 HydrophobicContact CD1-CE3 3.59Å; F970-W1020 AromaticContact CD1-CH2 3.28Å; F970-W1020 HydrophobicContact CD1-CH2 3.28Å; F970-W1020 AromaticContact CD1-CZ2 3.9Å; F970-W1020 HydrophobicContact CD1-CZ2 3.9Å; F970-W1020 AromaticContact CD1-CZ3 3.11Å; F970-W1020 HydrophobicContact CD1-CZ3 3.11Å; F970-W1020 HydrophobicContact CD2-CH2 4.1Å; F970-W1020 HydrophobicContact CD2-CZ2 4.26Å; F970-W1020 HydrophobicContact CE1-CE3 4.48Å; F970-W1020 AromaticContact CE1-CH2 3.88Å; F970-W1020 HydrophobicContact CE1-CH2 3.88Å; F970-W1020 AromaticContact CE1-CZ3 3.7Å; F970-W1020 HydrophobicContact CE1-CZ3 3.7Å; F970-W1020 HydrophobicContact CG-CD2 4.27Å; F970-W1020 AromaticContact CG-CE2 3.98Å; F970-W1020 HydrophobicContact CG-CE3 4.12Å; F970-W1020 AromaticContact CG-CH2 3.39Å; F970-W1020 HydrophobicContact CG-CH2 3.39Å; F970-W1020 AromaticContact CG-CZ2 3.55Å; F970-W1020 HydrophobicContact CG-CZ2 3.55Å; F970-W1020 AromaticContact CG-CZ3 3.71Å; F970-W1020 HydrophobicContact CG-CZ3 3.71Å; F970-W1020 PolarHBondContact N-O 3.48Å; F970-W1020 PolarHBondContact O-N 3.3Å; F970-W1020 VanDerWaalsContact O-O 3.07Å; W1020-Y1028 CarbonylContact C-O 3.5Å; W1020-Y1028 VanDerWaalsContact CA-O 3.28Å; W1020-Y1028 WeakPolarHBondContact CA-O 3.18Å
1021G71.5Confident61.5Low4 Ų468.9 Ų68.94%0.04136%0.362CS..EExtended strand (participates in β ladder)trans-169-175.3166.900000113.4E968 K1027 Y1028E968-G1021 WeakPolarHBondContact O-CA 3.48Å; G1021-K1027 WeakPolarHBondContact O-CA 3.3Å; G1021-Y1028 VanDerWaalsContact N-CE2 3.32Å; G1021-Y1028 PolarHBondContact N-O 3.02Å; G1021-Y1028 WeakPolarHBondContact O-CD1 3.24Å; G1021-Y1028 PolarHBondContact O-N 3.12Å
1022K63.4Low61.6Low95 Ų9566.1 Ų66.141%0.41336%0.355SS..EExtended strand (participates in β ladder)trans-130.6129.2177.3-169.4-177.4177.8-168.10109E968 G1024 D1026 K1027E968-K1022 PolarHBondContact O-N 2.77Å; K1022-G1024 VanDerWaalsContact CE-O 3.24Å; K1022-G1024 WeakPolarHBondContact CE-O 3.36Å; K1022-D1026 CarbonylContact C-O 3.53Å; K1022-D1026 VanDerWaalsContact CA-O 3.28Å; K1022-D1026 WeakPolarHBondContact CA-O 3.27Å; K1022-K1027 HydrophobicContact CB-CG 4.44Å; K1022-K1027 HydrophobicContact CD-CG 4.49Å; K1022-K1027 HydrophobicContact CG-CG 4.11Å
1023Q66Low62Low109 Ų10965.4 Ų65.451%0.50935%0.35SS..EExtended strand (participates in β ladder)trans-122.7111174-174.5173.85.800108.3N1025 D1026 Y1028Q1023-N1025 PolarHBondContact O-N 2.95Å; Q1023-D1026 PolarHBondContact N-O 3.46Å; Q1023-D1026 PolarHBondContact O-N 2.98Å; Q1023-D1026 VanDerWaalsContact O-N 3.09Å; Q1023-Y1028 HydrophobicContact CB-CD1 4.38Å; Q1023-Y1028 HydrophobicContact CB-CE1 4.15Å
1024G67.9Low62Low65 Ų6567.1 Ų67.167%0.6737%0.368SS*.THydrogen-bonded Turntrans64.8-126.2-16900000111K1022K1022-G1024 VanDerWaalsContact CE-O 3.24Å; K1022-G1024 WeakPolarHBondContact CE-O 3.36Å
1025N69.8Low62.2Low144 Ų14467 Ų6777%0.7735%0.352SS*.THydrogen-bonded Turntrans-87-14.1171.8-80.9-16.2000113.1Q1023Q1023-N1025 PolarHBondContact O-N 2.95Å
1026D61.3Low61.7Low115 Ų11569.4 Ų69.462%0.61536%0.363SS*.EExtended strand (participates in β ladder)trans-87.4130.4-169.2-57.4-42.1000110.5K1022 Q1023K1022-D1026 CarbonylContact C-O 3.53Å; K1022-D1026 VanDerWaalsContact CA-O 3.28Å; K1022-D1026 WeakPolarHBondContact CA-O 3.27Å; Q1023-D1026 PolarHBondContact N-O 3.46Å; Q1023-D1026 PolarHBondContact O-N 2.98Å; Q1023-D1026 VanDerWaalsContact O-N 3.09Å
1027K64.7Low61.4Low103 Ų10362.5 Ų62.545%0.44835%0.345SS..EExtended strand (participates in β ladder)trans-98.6142.6174.9-67.6171178.3-177.30109.4G1021 K1022 Y1049G1021-K1027 WeakPolarHBondContact O-CA 3.3Å; K1022-K1027 HydrophobicContact CB-CG 4.44Å; K1022-K1027 HydrophobicContact CD-CG 4.49Å; K1022-K1027 HydrophobicContact CG-CG 4.11Å; K1027-Y1049 HydrophobicContact CB-CD1 3.91Å; K1027-Y1049 HydrophobicContact CB-CE1 3.32Å; K1027-Y1049 HydrophobicContact CD-CE1 3.53Å; K1027-Y1049 WeakPolarHBondContact CD-OH 3.36Å; K1027-Y1049 HydrophobicContact CG-CE1 4.11Å; K1027-Y1049 PolarHBondContact NZ-OH 3.25Å
1028Y63.8Low60.7Low29 Ų2965.2 Ų65.211%0.11436%0.361CS..EExtended strand (participates in β ladder)trans-136.4152.5-177.164.7-100.9000111.7W1020 G1021 Q1023 L1030 Q1046 V1047W1020-Y1028 CarbonylContact C-O 3.5Å; W1020-Y1028 VanDerWaalsContact CA-O 3.28Å; W1020-Y1028 WeakPolarHBondContact CA-O 3.18Å; G1021-Y1028 VanDerWaalsContact N-CE2 3.32Å; G1021-Y1028 PolarHBondContact N-O 3.02Å; G1021-Y1028 WeakPolarHBondContact O-CD1 3.24Å; G1021-Y1028 PolarHBondContact O-N 3.12Å; Q1023-Y1028 HydrophobicContact CB-CD1 4.38Å; Q1023-Y1028 HydrophobicContact CB-CE1 4.15Å; Y1028-L1030 HydrophobicContact CE2-CD2 4.48Å; Y1028-L1030 HydrophobicContact CE2-CG 4.18Å; Y1028-Q1046 HydrophobicContact CD2-CB 4.43Å; Y1028-Q1046 HydrophobicContact CD2-CG 3.84Å; Y1028-Q1046 HydrophobicContact CE2-CG 4.33Å; Y1028-Q1046 HydrophobicContact CG-CG 4.5Å; Y1028-Q1046 VanDerWaalsContact CG-OE1 3.29Å; Y1028-V1047 WeakPolarHBondContact CA-O 3.32Å
1029C59.4Low59.7Low40 Ų4066.2 Ų66.227%0.2736%0.361SS..EExtended strand (participates in β ladder)trans-102.9138166.4-70.50000109.8I1017 V1031 Q1046 V1047I1017-C1029 HydrophobicContact CG2-CB 4.19Å; C1029-V1031 HydrophobicContact CB-CG2 4.44Å; C1029-Q1046 VanDerWaalsContact O-CA 3.25Å; C1029-Q1046 WeakPolarHBondContact O-CA 3.17Å; C1029-V1047 PolarHBondContact N-O 3.21Å; C1029-V1047 VanDerWaalsContact N-O 3.17Å; C1029-V1047 PolarHBondContact O-N 3.37Å
1030L60.6Low58.6Low17 Ų1773.6 Ų73.69%0.08940%0.395CS..EExtended strand (participates in β ladder)trans-81.7123.8168.6-72.4162.6000108.9D971 I1017 V1018 G1019 Y1028 Q1046D971-L1030 HydrophobicContact CB-CD1 4.33Å; I1017-L1030 CarbonylContact C-O 3.43Å; I1017-L1030 WeakPolarHBondContact CA-O 3.18Å; V1018-L1030 HydrophobicContact CG2-CB 3.83Å; V1018-L1030 PolarHBondContact N-O 3.33Å; G1019-L1030 PolarHBondContact O-N 2.91Å; Y1028-L1030 HydrophobicContact CE2-CD2 4.48Å; Y1028-L1030 HydrophobicContact CE2-CG 4.18Å; L1030-Q1046 HydrophobicContact CD2-CG 3.78Å; L1030-Q1046 HydrophobicContact CG-CG 4.41Å
1031V60.3Low57.3Low8 Ų873.5 Ų73.55%0.04840%0.398CS..EExtended strand (participates in β ladder)trans-122.7136.7-175.1-177.60000111V1015 R1016 I1017 C1029 L1045 V1047V1015-V1031 HydrophobicContact CB-CG1 3.31Å; V1015-V1031 HydrophobicContact CG1-CG1 4.06Å; V1015-V1031 HydrophobicContact CG2-CG1 3.35Å; V1015-V1031 HydrophobicContact CG2-CG2 4.4Å; R1016-V1031 CarbonylContact O-C 2.92Å; R1016-V1031 VanDerWaalsContact O-CA 3.3Å; R1016-V1031 WeakPolarHBondContact O-CA 3.49Å; I1017-V1031 HydrophobicContact CG1-CG2 4.48Å; C1029-V1031 HydrophobicContact CB-CG2 4.44Å; V1031-L1045 WeakPolarHBondContact CA-O 3.43Å; V1031-L1045 HydrophobicContact CB-CB 4.39Å; V1031-L1045 VanDerWaalsContact CB-O 3.24Å; V1031-L1045 WeakPolarHBondContact CB-O 3.2Å; V1031-L1045 PolarHBondContact N-O 2.96Å; V1031-L1045 PolarHBondContact O-N 3.21Å; V1031-L1045 VanDerWaalsContact O-N 3.1Å; V1031-V1047 HydrophobicContact CG2-CG2 4.23Å
1032A57.7Low56.1Low33 Ų3376 Ų7627%0.27341%0.41SS..EExtended strand (participates in β ladder)trans-110.1122.4166.600000108.2R1016 V1018R1016-A1032 HydrophobicContact CB-CB 4.45Å; R1016-A1032 WeakPolarHBondContact CB-O 3.35Å; R1016-A1032 PolarHBondContact N-O 2.76Å; R1016-A1032 PolarHBondContact O-N 3.43Å; V1018-A1032 HydrophobicContact CG1-CB 4.07Å
1033D59Low55.2Low26 Ų2671.6 Ų71.614%0.13939%0.392CS..  trans-98.6165.6179.5-150.5-28.9000110.9H1013 V1015 W1035 W1039 G1043H1013-D1033 IonicContact CD2-OD1 3.39Å; H1013-D1033 PolarHBondContact CD2-OD1 3.45Å; H1013-D1033 IonicContact CD2-OD2 3.58Å; H1013-D1033 PolarHBondContact CD2-OD2 3.4Å; H1013-D1033 IonicContact CE1-OD1 3.66Å; H1013-D1033 IonicContact NE2-OD1 2.74Å; H1013-D1033 PolarHBondContact NE2-OD1 3.35Å; H1013-D1033 IonicContact NE2-OD2 3.63Å; H1013-D1033 PolarHBondContact NE2-OD2 3.47Å; V1015-D1033 WeakPolarHBondContact CG1-OD2 3.25Å; D1033-W1035 VanDerWaalsContact C-N 3.32Å; D1033-W1039 HydrophobicContact CB-CZ3 4.31Å; D1033-G1043 PolarHBondContact N-O 3.27Å; D1033-G1043 VanDerWaalsContact N-O 3.11Å
1034S56.5Low54.3Low95 Ų9570 Ų7066%0.66438%0.384SS*.SBendtrans-84-1.417457.40000114.1
1035W51.8Low53.4Low68 Ų6869.6 Ų69.626%0.25837%0.366SS..SBendtrans-76144.9174.9-61.1-9.2000110F929 M941 H1013 D1033 W1039F929-W1035 HydrophobicContact CZ-CH2 4.33Å; F929-W1035 HydrophobicContact CZ-CZ3 4.43Å; M941-W1035 HydrophobicContact SD-CH2 4.09Å; M941-W1035 HydrophobicContact SD-CZ2 3.97Å; H1013-W1035 AromaticContact CD2-CZ2 3.94Å; H1013-W1035 AromaticContact CE1-NE1 3.62Å; H1013-W1035 AromaticContact NE2-CE2 3.76Å; H1013-W1035 AromaticContact NE2-NE1 3.36Å; H1013-W1035 PolarHBondContact NE2-NE1 2.88Å; D1033-W1035 VanDerWaalsContact C-N 3.32Å; W1035-W1039 HydrophobicContact CB-CB 4.07Å; W1035-W1039 HydrophobicContact CB-CD2 4.36Å; W1035-W1039 HydrophobicContact CB-CG 4.12Å; W1035-W1039 HydrophobicContact CD2-CD2 4.46Å; W1035-W1039 AromaticContact CE3-CD1 3.64Å; W1035-W1039 AromaticContact CE3-CD2 3.48Å; W1035-W1039 HydrophobicContact CE3-CD2 3.48Å; W1035-W1039 VanDerWaalsContact CE3-CD2 3.48Å; W1035-W1039 AromaticContact CE3-CE2 3.15Å; W1035-W1039 HydrophobicContact CE3-CE3 4.04Å; W1035-W1039 AromaticContact CE3-CG 3.83Å; W1035-W1039 HydrophobicContact CE3-CG 3.83Å; W1035-W1039 HydrophobicContact CE3-CH2 4.02Å; W1035-W1039 AromaticContact CE3-CZ2 3.48Å; W1035-W1039 HydrophobicContact CE3-CZ2 3.48Å; W1035-W1039 VanDerWaalsContact CE3-CZ2 3.48Å; W1035-W1039 HydrophobicContact CE3-CZ3 4.28Å; W1035-W1039 AromaticContact CE3-NE1 3.26Å; W1035-W1039 VanDerWaalsContact CE3-NE1 3.26Å; W1035-W1039 HydrophobicContact CH2-CZ2 4.45Å; W1035-W1039 HydrophobicContact CZ3-CD2 4.15Å; W1035-W1039 AromaticContact CZ3-CE2 3.33Å; W1035-W1039 AromaticContact CZ3-CH2 3.98Å; W1035-W1039 HydrophobicContact CZ3-CH2 3.98Å; W1035-W1039 AromaticContact CZ3-CZ2 3.26Å; W1035-W1039 HydrophobicContact CZ3-CZ2 3.26Å; W1035-W1039 AromaticContact CZ3-NE1 3.41Å
1036D46.9Very low52.5Low119 Ų11965.4 Ų65.464%0.63634%0.342SS*.  trans-52.6157.2-176-160.7-4.5000111.5D1038 W1039D1036-D1038 PolarHBondContact O-N 3.23Å; D1036-W1039 WeakPolarHBondContact O-CB 2.97Å; D1036-W1039 PolarHBondContact O-N 3.14Å
1037A46.6Very low52Low39 Ų3963.2 Ų63.232%0.32233%0.332SS..THydrogen-bonded Turntrans-61.6-16-179.800000113.3W1039 D1042A1037-W1039 PolarHBondContact O-N 3.26Å; A1037-D1042 HydrophobicContact CB-CB 4.18Å; A1037-D1042 WeakPolarHBondContact O-CA 3.13Å; A1037-D1042 PolarHBondContact O-N 2.89Å
1038D42.2Very low50.9Low143 Ų14361.5 Ų61.577%0.76533%0.333SS*.THydrogen-bonded Turntrans-73.3-13.1172.4-68.5-14.6000112.7D1036D1036-D1038 PolarHBondContact O-N 3.23Å
1039W40.9Very low50Low53 Ų5366 Ų6620%0.20135%0.35CS..THydrogen-bonded Turntrans-69.4130.7164.6-160.667.1000109D1033 W1035 D1036 A1037 E1041 D1042 G1043 L1045D1033-W1039 HydrophobicContact CB-CZ3 4.31Å; W1035-W1039 HydrophobicContact CB-CB 4.07Å; W1035-W1039 HydrophobicContact CB-CD2 4.36Å; W1035-W1039 HydrophobicContact CB-CG 4.12Å; W1035-W1039 HydrophobicContact CD2-CD2 4.46Å; W1035-W1039 AromaticContact CE3-CD1 3.64Å; W1035-W1039 AromaticContact CE3-CD2 3.48Å; W1035-W1039 HydrophobicContact CE3-CD2 3.48Å; W1035-W1039 VanDerWaalsContact CE3-CD2 3.48Å; W1035-W1039 AromaticContact CE3-CE2 3.15Å; W1035-W1039 HydrophobicContact CE3-CE3 4.04Å; W1035-W1039 AromaticContact CE3-CG 3.83Å; W1035-W1039 HydrophobicContact CE3-CG 3.83Å; W1035-W1039 HydrophobicContact CE3-CH2 4.02Å; W1035-W1039 AromaticContact CE3-CZ2 3.48Å; W1035-W1039 HydrophobicContact CE3-CZ2 3.48Å; W1035-W1039 VanDerWaalsContact CE3-CZ2 3.48Å; W1035-W1039 HydrophobicContact CE3-CZ3 4.28Å; W1035-W1039 AromaticContact CE3-NE1 3.26Å; W1035-W1039 VanDerWaalsContact CE3-NE1 3.26Å; W1035-W1039 HydrophobicContact CH2-CZ2 4.45Å; W1035-W1039 HydrophobicContact CZ3-CD2 4.15Å; W1035-W1039 AromaticContact CZ3-CE2 3.33Å; W1035-W1039 AromaticContact CZ3-CH2 3.98Å; W1035-W1039 HydrophobicContact CZ3-CH2 3.98Å; W1035-W1039 AromaticContact CZ3-CZ2 3.26Å; W1035-W1039 HydrophobicContact CZ3-CZ2 3.26Å; W1035-W1039 AromaticContact CZ3-NE1 3.41Å; D1036-W1039 WeakPolarHBondContact O-CB 2.97Å; D1036-W1039 PolarHBondContact O-N 3.14Å; A1037-W1039 PolarHBondContact O-N 3.26Å; W1039-E1041 PolarHBondContact O-N 3.41Å; W1039-D1042 PolarHBondContact O-N 2.04Å; W1039-G1043 PolarHBondContact O-N 2.68Å; W1039-L1045 HydrophobicContact CH2-CB 4.33Å; W1039-L1045 HydrophobicContact CH2-CD1 4.39Å; W1039-L1045 HydrophobicContact CH2-CD2 4.34Å; W1039-L1045 HydrophobicContact CZ3-CB 4.21Å
1040E43.8Very low48.7Very low157 Ų15773 Ų7373%0.73438%0.38SS*.Hα-helixtrans-34.4128-167.7-66.4-172.3168.100113.3
1041E50Low47.3Very low81 Ų8180.5 Ų80.538%0.37943%0.433SS..Hα-helixtrans63.341.3-176.5-47.3-154.3140.500117.5L999 G1000 W1039 G1043L999-E1041 WeakPolarHBondContact CA-OE1 3.4Å; L999-E1041 PolarHBondContact N-OE1 3.08Å; L999-E1041 PolarHBondContact N-OE2 3.44Å; G1000-E1041 PolarHBondContact N-OE1 3.05Å; G1000-E1041 PolarHBondContact N-OE2 2.85Å; W1039-E1041 PolarHBondContact O-N 3.41Å; E1041-G1043 PolarHBondContact O-N 2.67Å
1042D45.6Very low46.7Very low56 Ų5684.2 Ų84.230%0.29945%0.453SS..Hα-helixtrans6139.8179.5-65.5-40.2000112.6R995 A1037 W1039R995-D1042 IonicContact NH1-OD1 3.31Å; A1037-D1042 HydrophobicContact CB-CB 4.18Å; A1037-D1042 WeakPolarHBondContact O-CA 3.13Å; A1037-D1042 PolarHBondContact O-N 2.89Å; W1039-D1042 PolarHBondContact O-N 2.04Å
1043G43.7Very low46.1Very low3 Ų386.8 Ų86.83%0.03146%0.462CS..Hα-helixtrans81.323.7171.600000116.1D1033 W1039 E1041D1033-G1043 PolarHBondContact N-O 3.27Å; D1033-G1043 VanDerWaalsContact N-O 3.11Å; W1039-G1043 PolarHBondContact O-N 2.68Å; E1041-G1043 PolarHBondContact O-N 2.67Å
1044K48.3Very low45.4Very low77 Ų7790.2 Ų90.234%0.33548%0.48SS..EExtended strand (participates in β ladder)trans-121.6136.7-168.7-63.8166.3-162.1140.50112.9
1045L48.9Very low44.7Very low55 Ų5589.9 Ų89.929%0.28847%0.469SS..EExtended strand (participates in β ladder)trans-132.8144.2-175.8-175.270.4000111.2V1031 W1039 V1047V1031-L1045 WeakPolarHBondContact CA-O 3.43Å; V1031-L1045 HydrophobicContact CB-CB 4.39Å; V1031-L1045 VanDerWaalsContact CB-O 3.24Å; V1031-L1045 WeakPolarHBondContact CB-O 3.2Å; V1031-L1045 PolarHBondContact N-O 2.96Å; V1031-L1045 PolarHBondContact O-N 3.21Å; V1031-L1045 VanDerWaalsContact O-N 3.1Å; W1039-L1045 HydrophobicContact CH2-CB 4.33Å; W1039-L1045 HydrophobicContact CH2-CD1 4.39Å; W1039-L1045 HydrophobicContact CH2-CD2 4.34Å; W1039-L1045 HydrophobicContact CZ3-CB 4.21Å; L1045-V1047 HydrophobicContact CD2-CG2 3.61Å; L1045-V1047 HydrophobicContact CG-CG2 3.99Å
1046Q50.8Low44.2Very low57 Ų5791.3 Ų91.327%0.26648%0.482SS..EExtended strand (participates in β ladder)trans-109.4133.4157.6-79-1768.600110Y1028 C1029 L1030Y1028-Q1046 HydrophobicContact CD2-CB 4.43Å; Y1028-Q1046 HydrophobicContact CD2-CG 3.84Å; Y1028-Q1046 HydrophobicContact CE2-CG 4.33Å; Y1028-Q1046 HydrophobicContact CG-CG 4.5Å; Y1028-Q1046 VanDerWaalsContact CG-OE1 3.29Å; C1029-Q1046 VanDerWaalsContact O-CA 3.25Å; C1029-Q1046 WeakPolarHBondContact O-CA 3.17Å; L1030-Q1046 HydrophobicContact CD2-CG 3.78Å; L1030-Q1046 HydrophobicContact CG-CG 4.41Å
1047V50.8Low44.1Very low68 Ų6889.5 Ų89.541%0.41247%0.472SS..EExtended strand (participates in β ladder)trans-111.5122.3179.8-1750000108.8Y1028 C1029 V1031 L1045Y1028-V1047 WeakPolarHBondContact CA-O 3.32Å; C1029-V1047 PolarHBondContact N-O 3.21Å; C1029-V1047 VanDerWaalsContact N-O 3.17Å; C1029-V1047 PolarHBondContact O-N 3.37Å; V1031-V1047 HydrophobicContact CG2-CG2 4.23Å; L1045-V1047 HydrophobicContact CD2-CG2 3.61Å; L1045-V1047 HydrophobicContact CG-CG2 3.99Å
1048S42.4Very low43.9Very low67 Ų6793.1 Ų93.147%0.46948%0.483SS..EExtended strand (participates in β ladder)trans-72.5134.2167.162.10000109.2
1049Y44.6Very low44Very low123 Ų12389.2 Ų89.248%0.48246%0.461SS..PPolyproline II helixtrans-98.2125.3168.483.8-94.6000109.2K1027K1027-Y1049 HydrophobicContact CB-CD1 3.91Å; K1027-Y1049 HydrophobicContact CB-CE1 3.32Å; K1027-Y1049 HydrophobicContact CD-CE1 3.53Å; K1027-Y1049 WeakPolarHBondContact CD-OH 3.36Å; K1027-Y1049 HydrophobicContact CG-CE1 4.11Å; K1027-Y1049 PolarHBondContact NZ-OH 3.25Å
1050E31.7Very low44.3Very low189 Ų18992.3 Ų92.388%0.88348%0.483SS*.PPolyproline II helixtrans-83.3139.3152.7-80.2-173.1164.300107
1051S31Very low44.3Very low174 Ų17486.4 Ų86.4100%1.21746%0.46SS*.  trans-46.80-169.658.10000115.6

Retrieved 1,051 of 1,051 residues in 662.5 ms (Link to these results)