A0A077Z3B9_TRITR Loading...

Carboxylesterase

AlphaFold DB , UniProt , Accession A0A077Z3B9, Species TRITR (Trichuris trichiura, Whipworm), Gene n/a, Length 705 aa.

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Site Residue pLDDT pLDDT confidence pLDDT10 pLDDT10 confidence SASA SASA [Ų] SASA10 SASA10 [Ų] RSA RSA unformatted RSA10 RSA10 unformatted Surface Surface10 (not used) Disorder (not used) Disorder Sec. str. Secondary structure Isomer Phi (φ) Psi (ψ) Omega (ω) Chi 1 (χ1) Chi 2 (χ2) Chi 3 (χ3) Chi 4 (χ4) Chi 5 (χ5) Tau (τ) Contacts (colored by PAE) Contact details
1M45.3Very low48Very low221 Ų221132.5 Ų132.5100%1.08973%0.734SS**  0-27.40-97.4175.3139.700114L3 K4M1-L3 PolarHBondContact O-N 3.44Å; M1-K4 PolarHBondContact O-N 3.46Å
2L46.7Very low47.7Very low155 Ų155134 Ų13481%0.81274%0.738SS**G310 helixtrans-64.6-27.8-177-115.977.9000116.1K4L2-K4 PolarHBondContact O-N 3.34Å
3L49.6Very low47.5Very low164 Ų164130.1 Ų130.186%0.85973%0.726SS**G310 helixtrans-75.8-16.7-178.5-102.987.4000114.9M1M1-L3 PolarHBondContact O-N 3.44Å
4K48.6Very low47.5Very low184 Ų184129.9 Ų129.980%0.872%0.721SS**G310 helixtrans-87.1-14.7-177.7-76.8-169.5174.4-174.10114.2M1 L2M1-K4 PolarHBondContact O-N 3.46Å; L2-K4 PolarHBondContact O-N 3.34Å
5L46.4Very low47.2Very low133 Ų133133.4 Ų133.470%0.69673%0.726SS**THydrogen-bonded Turntrans-81.9-23.5178.7-98.3121.3000113.7S7L5-S7 VanDerWaalsContact C-N 3.29Å; L5-S7 PolarHBondContact O-N 3.41Å
6V53.5Low46.9Very low111 Ų111131.3 Ų131.367%0.67372%0.724SS**Hα-helixtrans-72.8-24.7-178.3-176.90000111.9
7S50.9Low46.6Very low89 Ų89131.1 Ų131.162%0.62273%0.727SS**Hα-helixtrans-82-14-177.8-147.40000114.6L5L5-S7 VanDerWaalsContact C-N 3.29Å; L5-S7 PolarHBondContact O-N 3.41Å
8C44.7Very low46.3Very low92 Ų92128.4 Ų128.462%0.62272%0.719SS**Hα-helixtrans-87.1-20177.2-81.10000113.6
9L47.2Very low46.2Very low140 Ų140126.4 Ų126.473%0.73371%0.714SS**Hα-helixtrans-82.5-16.5178.5-79.4158.7000113.3
10A48Very low46.1Very low64 Ų64128.8 Ų128.853%0.52972%0.719SS.*THydrogen-bonded Turntrans-86-13.3179.200000114.4S13A10-S13 PolarHBondContact O-OG 3.43Å
11V47.4Very low46Very low105 Ų105130.4 Ų130.464%0.63672%0.721SS**THydrogen-bonded Turntrans-99.9-14.3-177-175.30000112.6
12L44.2Very low46.2Very low150 Ų150123.2 Ų123.279%0.78569%0.692SS**THydrogen-bonded Turntrans-85.9-2.9178.5-88.1154.3000114.4
13S45Very low46.2Very low83 Ų83125.1 Ų125.158%0.5870%0.697SS**THydrogen-bonded Turntrans-93.46.7-179.733.60000115A10A10-S13 PolarHBondContact O-OG 3.43Å
14I47.9Very low46.4Very low127 Ų127123.9 Ų123.965%0.65169%0.691SS**SBendtrans-104.2-6.1-176.2-60.2178.1000113.8
15F43.4Very low47.4Very low183 Ų183116.4 Ų116.480%0.80366%0.661SS**  trans-118.922.3-177.1-77.7-77.7000115.7V17F15-V17 PolarHBondContact O-N 3.08Å; F15-V17 VanDerWaalsContact O-N 3.08Å
16S41.6Very low49.3Very low99 Ų99111.7 Ų111.769%0.69264%0.64SS**  trans-81.576.8155.254.20000108S18S16-S18 PolarHBondContact O-N 2.79Å
17V42.1Very low51Low128 Ų128106.7 Ų106.778%0.77661%0.609SS**  trans-61.389.2149.9176.60000103.4F15 S19F15-V17 PolarHBondContact O-N 3.08Å; F15-V17 VanDerWaalsContact O-N 3.08Å; V17-S19 PolarHBondContact O-N 2.83Å
18S40.9Very low53.1Low84 Ų84106.3 Ų106.359%0.58760%0.604SS**  trans-55.8101.4163.5175.10000103.7S16 Q20S16-S18 PolarHBondContact O-N 2.79Å; S18-Q20 PolarHBondContact O-N 2.66Å
19S43.9Very low55.5Low90 Ų90102.2 Ų102.263%0.62958%0.576SS**  trans-55.593.4151.453.50000103.1V17 Q21V17-S19 PolarHBondContact O-N 2.83Å; S19-Q21 PolarHBondContact O-N 2.76Å
20Q44.7Very low57.8Low174 Ų174103.4 Ų103.481%0.81358%0.575SS**  trans-70.676.3175.8-158.2153.34.700104.2S18 C22S18-Q20 PolarHBondContact O-N 2.66Å; Q20-C22 VanDerWaalsContact C-N 3.32Å; Q20-C22 PolarHBondContact O-N 2.94Å
21Q44Very low60.1Low163 Ų163100.7 Ų100.776%0.76255%0.552SS**  trans-63.6105.3176.8-164.3162.32.900102.3S19 E23S19-Q21 PolarHBondContact O-N 2.76Å; Q21-E23 PolarHBondContact O-N 3.07Å
22C49.5Very low62.4Low69 Ų69100.4 Ų100.447%0.46655%0.55SS.*  trans-61.188.1-174.6173.50000108.1Q20 N24 C25Q20-C22 VanDerWaalsContact C-N 3.32Å; Q20-C22 PolarHBondContact O-N 2.94Å; C22-N24 PolarHBondContact O-N 2.71Å; C22-C25 HydrophobicContact CB-CB 3.89Å; C22-C25 WeakPolarHBondContact CB-SG 3.45Å; C22-C25 WeakPolarHBondContact O-CB 2.88Å; C22-C25 PolarHBondContact O-N 3.29Å; C22-C25 WeakPolarHBondContact SG-CA 3.41Å; C22-C25 WeakPolarHBondContact SG-CB 3.32Å; C22-C25 CovalentContact SG-SG 2.04Å; C22-C25 PolarHBondContact SG-SG 2.96Å
23E47.9Very low64.7Low195 Ų19593.7 Ų93.791%0.91152%0.516SS*.THydrogen-bonded Turntrans-63.8-13.3-175.7-82.1-179159.600112.1Q21Q21-E23 PolarHBondContact O-N 3.07Å
24N52.8Low67.1Low138 Ų13890.1 Ų90.174%0.73849%0.492SS*.THydrogen-bonded Turntrans-129.248178.5-133.911.7000111.5C22 S26C22-N24 PolarHBondContact O-N 2.71Å; N24-S26 PolarHBondContact O-N 3.12Å
25C70.8Confident69.5Low27 Ų2788.9 Ų88.918%0.18248%0.482CS..  trans-7636.5180-1070000114C22 H39 Y40C22-C25 HydrophobicContact CB-CB 3.89Å; C22-C25 WeakPolarHBondContact CB-SG 3.45Å; C22-C25 WeakPolarHBondContact O-CB 2.88Å; C22-C25 PolarHBondContact O-N 3.29Å; C22-C25 WeakPolarHBondContact SG-CA 3.41Å; C22-C25 WeakPolarHBondContact SG-CB 3.32Å; C22-C25 CovalentContact SG-SG 2.04Å; C22-C25 PolarHBondContact SG-SG 2.96Å; C25-H39 VanDerWaalsContact O-CA 3.23Å; C25-H39 WeakPolarHBondContact O-CA 3.49Å; C25-H39 WeakPolarHBondContact O-CB 3.23Å; C25-Y40 HydrophobicContact CB-CD2 4.22Å; C25-Y40 PolarHBondContact O-N 3.34Å
26S84.4Confident72.1Confident35 Ų3580.1 Ų80.125%0.24544%0.443CS..EExtended strand (participates in β ladder)trans-88.3144.2171.9800000111.1N24 E37 G38 Y40N24-S26 PolarHBondContact O-N 3.12Å; S26-E37 VanDerWaalsContact CB-CD 3.48Å; S26-E37 WeakPolarHBondContact CB-OE1 3.33Å; S26-E37 PolarHBondContact OG-OE1 2.82Å; S26-G38 CarbonylContact C-O 3.56Å; S26-G38 VanDerWaalsContact CA-O 3.32Å; S26-G38 WeakPolarHBondContact CA-O 3.06Å; S26-Y40 WeakPolarHBondContact O-CE2 3.41Å
27C90.1Very high74.8Confident5 Ų578.1 Ų78.13%0.03442%0.423CS..EExtended strand (participates in β ladder)trans-126.9124.6174.5610000109.3G38 Y40 R50 F52C27-G38 PolarHBondContact N-O 2.91Å; C27-G38 PolarHBondContact O-N 2.04Å; C27-G38 VanDerWaalsContact SG-C 3.55Å; C27-Y40 HydrophobicContact CB-CD2 4.44Å; C27-Y40 HydrophobicContact CB-CE1 4.15Å; C27-Y40 HydrophobicContact CB-CE2 3.99Å; C27-R50 HydrophobicContact CB-CG 4.31Å; C27-F52 WeakPolarHBondContact O-CE1 3.19Å; C27-F52 WeakPolarHBondContact SG-CZ 3.42Å
28T94.9Very high77.4Confident82 Ų8272 Ų7250%0.50339%0.386SS..EExtended strand (participates in β ladder)trans-98.2136.2-179.3-48.90000110.7K35 I36T28-K35 HydrophobicContact CG2-CB 4.23Å; T28-K35 HydrophobicContact CG2-CD 4.48Å; T28-I36 CarbonylContact C-O 3.59Å; T28-I36 VanDerWaalsContact CA-O 3.29Å; T28-I36 WeakPolarHBondContact CA-O 3.34Å; T28-I36 WeakPolarHBondContact CG2-O 3.29Å
29V95.8Very high80Confident6 Ų670.6 Ų70.64%0.03637%0.37CS..EExtended strand (participates in β ladder)trans-122.7138171.5170.20000108.9L31 K35 I36 F52 A201 F202V29-L31 HydrophobicContact CG1-CD2 3.79Å; V29-K35 WeakPolarHBondContact O-CA 3.29Å; V29-I36 HydrophobicContact CB-CD1 4.41Å; V29-I36 HydrophobicContact CB-CG1 3.99Å; V29-I36 PolarHBondContact N-O 3.06Å; V29-I36 PolarHBondContact O-N 2.74Å; V29-F52 HydrophobicContact CB-CE1 4.13Å; V29-F52 HydrophobicContact CB-CZ 4.12Å; V29-F52 HydrophobicContact CG2-CE1 3.82Å; V29-F52 HydrophobicContact CG2-CE2 4.03Å; V29-F52 HydrophobicContact CG2-CZ 3.32Å; V29-A201 HydrophobicContact CG1-CB 3.72Å; V29-F202 HydrophobicContact CB-CE1 4.39Å; V29-F202 HydrophobicContact CG1-CD1 4.42Å; V29-F202 HydrophobicContact CG1-CE1 4.15Å; V29-F202 HydrophobicContact CG1-CE2 4.31Å; V29-F202 HydrophobicContact CG1-CZ 4.1Å; V29-F202 HydrophobicContact CG2-CD1 4.33Å; V29-F202 HydrophobicContact CG2-CE1 4.37Å
30K95.7Very high82.5Confident164 Ų16470.5 Ų70.571%0.71336%0.356SS*.EExtended strand (participates in β ladder)trans-97.4116.6175.4-174.9-178.1178.8-175.20109.1K35K30-K35 HydrophobicContact CB-CG 4.46Å; K30-K35 HydrophobicContact CG-CG 4.38Å
31L96.4Very high84.9Confident8 Ų862.4 Ų62.44%0.04232%0.319CS..  trans-98.4171.6172.8-50.6-179.7000110.2V29 T33 G34 I36 I55 W76 W194 E198 A201 F202V29-L31 HydrophobicContact CG1-CD2 3.79Å; L31-T33 PolarHBondContact O-N 2.91Å; L31-G34 WeakPolarHBondContact CA-O 3.43Å; L31-G34 VanDerWaalsContact CB-O 3.31Å; L31-G34 WeakPolarHBondContact CB-O 3.34Å; L31-G34 PolarHBondContact N-O 2.83Å; L31-G34 PolarHBondContact O-N 2.86Å; L31-I36 HydrophobicContact CD1-CD1 4.11Å; L31-I36 HydrophobicContact CD1-CG1 4.37Å; L31-I36 HydrophobicContact CD1-CG2 3.81Å; L31-I36 HydrophobicContact CG-CD1 4.48Å; L31-I36 HydrophobicContact CG-CG1 4.45Å; L31-I36 HydrophobicContact CG-CG2 4.49Å; L31-I55 HydrophobicContact CD1-CG2 4.29Å; L31-W76 HydrophobicContact CD1-CH2 4.08Å; L31-W76 HydrophobicContact CD1-CZ2 4.36Å; L31-W194 HydrophobicContact CD1-CH2 4.49Å; L31-W194 HydrophobicContact CD1-CZ2 3.69Å; L31-W194 HydrophobicContact CD2-CZ2 4.46Å; L31-E198 WeakPolarHBondContact CA-OE2 3.49Å; L31-E198 WeakPolarHBondContact CB-OE2 3.12Å; L31-E198 HydrophobicContact CD2-CB 4.2Å; L31-A201 HydrophobicContact CD2-CB 4.21Å; L31-F202 HydrophobicContact CD2-CE2 3.53Å; L31-F202 HydrophobicContact CD2-CZ 3.72Å
32T94.4Very high87.2Confident98 Ų9858 Ų5860%0.60130%0.304SS*.SBendtrans-66-29.7172.373.20000112.5R197 E198T32-R197 HydrophobicContact CG2-CG 4.43Å; T32-E198 WeakPolarHBondContact CB-OE1 3.29Å; T32-E198 WeakPolarHBondContact CG2-OE1 3.38Å; T32-E198 PolarHBondContact N-OE2 3.5Å; T32-E198 PolarHBondContact OG1-OE1 3.25Å
33T93Very high89.2Confident10 Ų1055.6 Ų55.66%0.06129%0.286CS..SBendtrans-83.4-19.7179.5540000113.6L31 S75 W76L31-T33 PolarHBondContact O-N 2.91Å; T33-S75 CarbonylContact O-C 3.57Å; T33-S75 WeakPolarHBondContact O-CA 3.31Å; T33-S75 VanDerWaalsContact O-CB 3.26Å; T33-S75 WeakPolarHBondContact O-CB 3.47Å; T33-S75 PolarHBondContact O-OG 3.24Å; T33-W76 PolarHBondContact O-N 3.32Å; T33-W76 WeakPolarHBondContact OG1-CH2 3.42Å; T33-W76 WeakPolarHBondContact OG1-CZ3 3.37Å
34G95.3Very high91.3Very high8 Ų854 Ų548%0.08228%0.283CS..  trans152.9-173.9-179.800000112.5L31L31-G34 WeakPolarHBondContact CA-O 3.43Å; L31-G34 VanDerWaalsContact CB-O 3.31Å; L31-G34 WeakPolarHBondContact CB-O 3.34Å; L31-G34 PolarHBondContact N-O 2.83Å; L31-G34 PolarHBondContact O-N 2.86Å
35K97.7Very high93Very high100 Ų10050.9 Ų50.944%0.43528%0.284SS..EExtended strand (participates in β ladder)trans-88.7140.4177.7-67.9177.3-176.91740110.7T28 V29 K30 W76 V80 L81T28-K35 HydrophobicContact CG2-CB 4.23Å; T28-K35 HydrophobicContact CG2-CD 4.48Å; V29-K35 WeakPolarHBondContact O-CA 3.29Å; K30-K35 HydrophobicContact CB-CG 4.46Å; K30-K35 HydrophobicContact CG-CG 4.38Å; K35-W76 PolarHBondContact O-NE1 3.16Å; K35-V80 HydrophobicContact CB-CG1 4.39Å; K35-V80 HydrophobicContact CB-CG2 4.06Å; K35-V80 HydrophobicContact CD-CG2 4.34Å; K35-V80 WeakPolarHBondContact O-CA 3.44Å; K35-L81 PolarHBondContact O-N 2.97Å
36I98.1Very high94Very high0 Ų053.1 Ų53.10%030%0.3CS..EExtended strand (participates in β ladder)trans-118.3151.3169.363.4172.2000110.2T28 V29 L31 F52 I55 W76 L81 F202T28-I36 CarbonylContact C-O 3.59Å; T28-I36 VanDerWaalsContact CA-O 3.29Å; T28-I36 WeakPolarHBondContact CA-O 3.34Å; T28-I36 WeakPolarHBondContact CG2-O 3.29Å; V29-I36 HydrophobicContact CB-CD1 4.41Å; V29-I36 HydrophobicContact CB-CG1 3.99Å; V29-I36 PolarHBondContact N-O 3.06Å; V29-I36 PolarHBondContact O-N 2.74Å; L31-I36 HydrophobicContact CD1-CD1 4.11Å; L31-I36 HydrophobicContact CD1-CG1 4.37Å; L31-I36 HydrophobicContact CD1-CG2 3.81Å; L31-I36 HydrophobicContact CG-CD1 4.48Å; L31-I36 HydrophobicContact CG-CG1 4.45Å; L31-I36 HydrophobicContact CG-CG2 4.49Å; I36-F52 HydrophobicContact CD1-CB 4.29Å; I36-F52 HydrophobicContact CD1-CD1 3.46Å; I36-F52 VanDerWaalsContact CD1-CD1 3.46Å; I36-F52 HydrophobicContact CD1-CE1 4.02Å; I36-F52 HydrophobicContact CD1-CG 4.02Å; I36-F52 HydrophobicContact CG1-CD1 3.88Å; I36-F52 HydrophobicContact CG1-CE1 4.05Å; I36-I55 HydrophobicContact CD1-CD1 3.74Å; I36-I55 HydrophobicContact CD1-CG1 3.87Å; I36-W76 HydrophobicContact CG2-CH2 3.99Å; I36-W76 HydrophobicContact CG2-CZ2 3.49Å; I36-W76 VanDerWaalsContact CG2-CZ2 3.49Å; I36-L81 CarbonylContact C-O 3.58Å; I36-L81 WeakPolarHBondContact CA-O 3.36Å; I36-L81 HydrophobicContact CG2-CB 4.26Å; I36-F202 HydrophobicContact CD1-CE1 3.81Å; I36-F202 HydrophobicContact CD1-CZ 3.64Å
37E97.8Very high94.4Very high56 Ų5654.4 Ų54.426%0.26231%0.306SS..EExtended strand (participates in β ladder)trans-120.2120.3173.3-173.2-172.4-119.200110S26 V80 L81 C83 H84S26-E37 VanDerWaalsContact CB-CD 3.48Å; S26-E37 WeakPolarHBondContact CB-OE1 3.33Å; S26-E37 PolarHBondContact OG-OE1 2.82Å; E37-V80 HydrophobicContact CB-CG1 3.75Å; E37-L81 PolarHBondContact N-O 3.2Å; E37-C83 CarbonylContact O-C 3.55Å; E37-C83 WeakPolarHBondContact O-CA 3.37Å; E37-C83 WeakPolarHBondContact O-CB 2.89Å; E37-C83 PolarHBondContact O-N 2.83Å; E37-H84 IonicContact OE2-CD2 3.93Å; E37-H84 IonicContact OE2-CE1 3.72Å; E37-H84 IonicContact OE2-NE2 2.87Å; E37-H84 PolarHBondContact OE2-NE2 3.2Å
38G97.5Very high94.7Very high0 Ų055 Ų550%031%0.309CS..EExtended strand (participates in β ladder)trans-114.2-161.1169.800000110.7S26 C27 T51 H84S26-G38 CarbonylContact C-O 3.56Å; S26-G38 VanDerWaalsContact CA-O 3.32Å; S26-G38 WeakPolarHBondContact CA-O 3.06Å; C27-G38 PolarHBondContact N-O 2.91Å; C27-G38 PolarHBondContact O-N 2.04Å; C27-G38 VanDerWaalsContact SG-C 3.55Å; G38-T51 VanDerWaalsContact CA-O 3.32Å; G38-T51 WeakPolarHBondContact CA-O 3.44Å; G38-H84 VanDerWaalsContact C-CE1 3.46Å; G38-H84 PolarHBondContact O-CE1 3.31Å
39H95.7Very high94.7Very high54 Ų5451.1 Ų51.125%0.2529%0.285CS..EExtended strand (participates in β ladder)trans-129.7156.4179.457.9-86.9000112.6C25 T51 H84C25-H39 VanDerWaalsContact O-CA 3.23Å; C25-H39 WeakPolarHBondContact O-CA 3.49Å; C25-H39 WeakPolarHBondContact O-CB 3.23Å; H39-T51 PolarHBondContact N-O 2.99Å; H39-T51 WeakPolarHBondContact NE2-CB 3.43Å; H39-T51 PolarHBondContact O-N 2.9Å; H39-H84 AromaticContact ND1-ND1 3.74Å
40Y96Very high94.8Very high89 Ų8953.2 Ų53.235%0.34929%0.293SS..EExtended strand (participates in β ladder)trans-70133.4168.3-67.7-75.5000110.6C25 S26 C27 V47 G49 R50C25-Y40 HydrophobicContact CB-CD2 4.22Å; C25-Y40 PolarHBondContact O-N 3.34Å; S26-Y40 WeakPolarHBondContact O-CE2 3.41Å; C27-Y40 HydrophobicContact CB-CD2 4.44Å; C27-Y40 HydrophobicContact CB-CE1 4.15Å; C27-Y40 HydrophobicContact CB-CE2 3.99Å; Y40-V47 HydrophobicContact CD1-CG1 3.72Å; Y40-V47 HydrophobicContact CG-CG1 4.14Å; Y40-G49 CarbonylContact C-O 3.58Å; Y40-G49 WeakPolarHBondContact CA-O 3.26Å; Y40-R50 HydrophobicContact CD1-CG 3.96Å; Y40-R50 HydrophobicContact CE1-CG 4Å
41A94.9Very high94.9Very high4 Ų445.4 Ų45.43%0.03326%0.259CS..EExtended strand (participates in β ladder)trans-80.5125.7171.200000109.3V47 V48 G49 H149A41-V47 CarbonylContact O-C 3.52Å; A41-V47 WeakPolarHBondContact O-CA 3.34Å; A41-V48 HydrophobicContact CB-CG2 3.84Å; A41-V48 PolarHBondContact O-N 3.34Å; A41-G49 PolarHBondContact N-O 2.9Å; A41-H149 VanDerWaalsContact CB-CD2 3.42Å; A41-H149 WeakPolarHBondContact CB-CD2 3.41Å; A41-H149 VanDerWaalsContact CB-NE2 3.26Å; A41-H149 WeakPolarHBondContact CB-NE2 3.36Å
42V93.6Very high95Very high71 Ų7145 Ų4543%0.4326%0.257SS..EExtended strand (participates in β ladder)trans-120117.5-178.4-177.60000109.2S46 V47V42-S46 CarbonylContact C-O 3.53Å; V42-S46 VanDerWaalsContact CA-O 3.29Å; V42-S46 WeakPolarHBondContact CA-O 3.39Å; V42-V47 HydrophobicContact CG2-CG2 4.1Å
43I91.4Very high95.2Very high17 Ų1740.8 Ų40.89%0.08723%0.231CC..EExtended strand (participates in β ladder)trans-123129.6178.5-57.9-173.6000108G45 S46 V48 N146 H149 E150I43-G45 PolarHBondContact O-N 3.12Å; I43-G45 VanDerWaalsContact O-N 3.12Å; I43-S46 PolarHBondContact N-O 2.87Å; I43-S46 PolarHBondContact O-N 3.14Å; I43-V48 HydrophobicContact CB-CG1 3.98Å; I43-V48 HydrophobicContact CB-CG2 4.32Å; I43-V48 HydrophobicContact CD1-CG2 3.82Å; I43-V48 HydrophobicContact CG1-CG1 4.36Å; I43-V48 HydrophobicContact CG1-CG2 3.77Å; I43-N146 HydrophobicContact CD1-CB 4.3Å; I43-H149 HydrophobicContact CD1-CB 3.93Å; I43-E150 HydrophobicContact CD1-CG 3.54Å; I43-E150 HydrophobicContact CG2-CG 4.47Å; I43-E150 WeakPolarHBondContact CG2-OE1 3.22Å
44N90.4Very high95.4Very high162 Ų16240.3 Ų40.387%0.86623%0.228SC*.THydrogen-bonded Turntrans49.637.7-176.1-61.3-38.7000113.5S46N44-S46 VanDerWaalsContact C-N 3.26Å; N44-S46 PolarHBondContact O-N 2.84Å
45G89.5Confident95.6Very high72 Ų7240 Ų4074%0.74222%0.224SC*.THydrogen-bonded Turntrans78.1-1.1179.900000115.7I43I43-G45 PolarHBondContact O-N 3.12Å; I43-G45 VanDerWaalsContact O-N 3.12Å
46S91.4Very high95.6Very high75 Ų7535.5 Ų35.552%0.52421%0.205SC..EExtended strand (participates in β ladder)trans-105.1137177.3-580000110.8V42 I43 N44 V48V42-S46 CarbonylContact C-O 3.53Å; V42-S46 VanDerWaalsContact CA-O 3.29Å; V42-S46 WeakPolarHBondContact CA-O 3.39Å; I43-S46 PolarHBondContact N-O 2.87Å; I43-S46 PolarHBondContact O-N 3.14Å; N44-S46 VanDerWaalsContact C-N 3.26Å; N44-S46 PolarHBondContact O-N 2.84Å; S46-V48 PolarHBondContact O-N 3.13Å
47V93.7Very high95.7Very high61 Ų6135.5 Ų35.537%0.3721%0.205SC..EExtended strand (participates in β ladder)trans-67.7120.7168.9176.40000107.8Y40 A41 V42 N116Y40-V47 HydrophobicContact CD1-CG1 3.72Å; Y40-V47 HydrophobicContact CG-CG1 4.14Å; A41-V47 CarbonylContact O-C 3.52Å; A41-V47 WeakPolarHBondContact O-CA 3.34Å; V42-V47 HydrophobicContact CG2-CG2 4.1Å; V47-N116 PolarHBondContact O-ND2 3.06Å
48V95.2Very high95.7Very high18 Ų1833 Ų3311%0.10919%0.194CC..EExtended strand (participates in β ladder)trans-106.3-18.9-179.5-62.90000113.1A41 I43 S46 N116 H149 M154A41-V48 HydrophobicContact CB-CG2 3.84Å; A41-V48 PolarHBondContact O-N 3.34Å; I43-V48 HydrophobicContact CB-CG1 3.98Å; I43-V48 HydrophobicContact CB-CG2 4.32Å; I43-V48 HydrophobicContact CD1-CG2 3.82Å; I43-V48 HydrophobicContact CG1-CG1 4.36Å; I43-V48 HydrophobicContact CG1-CG2 3.77Å; S46-V48 PolarHBondContact O-N 3.13Å; V48-N116 VanDerWaalsContact C-CG 3.49Å; V48-N116 PolarHBondContact O-N 2.88Å; V48-N116 VanDerWaalsContact O-N 3.14Å; V48-H149 HydrophobicContact CG2-CB 4.11Å; V48-M154 HydrophobicContact CB-CG 3.92Å; V48-M154 HydrophobicContact CB-SD 4Å; V48-M154 HydrophobicContact CG1-CG 4.32Å; V48-M154 HydrophobicContact CG1-SD 3.81Å; V48-M154 HydrophobicContact CG2-SD 4.48Å
49G95.9Very high95.8Very high0 Ų034.6 Ų34.60%020%0.201CC..EExtended strand (participates in β ladder)trans177.1-162-177.500000113.5Y40 A41 A114 N116Y40-G49 CarbonylContact C-O 3.58Å; Y40-G49 WeakPolarHBondContact CA-O 3.26Å; A41-G49 PolarHBondContact N-O 2.9Å; G49-A114 CarbonylContact C-O 3.56Å; G49-A114 WeakPolarHBondContact CA-O 3.03Å; G49-N116 VanDerWaalsContact CA-OD1 3.29Å; G49-N116 WeakPolarHBondContact CA-OD1 3.1Å; G49-N116 PolarHBondContact N-OD1 2.9Å
50R97.3Very high95.9Very high50 Ų5033.5 Ų33.519%0.18920%0.199CC..EExtended strand (participates in β ladder)trans-124.5139.6178.9-61.5174.8-68.3163.8-0.1109.9C27 Y40 F52 A114 H149 F202C27-R50 HydrophobicContact CB-CG 4.31Å; Y40-R50 HydrophobicContact CD1-CG 3.96Å; Y40-R50 HydrophobicContact CE1-CG 4Å; R50-F52 HydrophobicContact CB-CE2 3.77Å; R50-F52 HydrophobicContact CB-CZ 4.42Å; R50-A114 PolarHBondContact N-O 3.19Å; R50-A114 PolarHBondContact O-N 3.35Å; R50-H149 PolarHBondContact O-CE1 2.79Å; R50-F202 PolarHBondContact NH2-O 3.1Å
51T98.2Very high96Very high1 Ų129.4 Ų29.41%0.00618%0.184CC..EExtended strand (participates in β ladder)trans-121.8129.7179.6-53.50000109.8G38 H39 L53 F113 H149G38-T51 VanDerWaalsContact CA-O 3.32Å; G38-T51 WeakPolarHBondContact CA-O 3.44Å; H39-T51 PolarHBondContact N-O 2.99Å; H39-T51 WeakPolarHBondContact NE2-CB 3.43Å; H39-T51 PolarHBondContact O-N 2.9Å; T51-L53 HydrophobicContact CG2-CD1 4.3Å; T51-L53 HydrophobicContact CG2-CD2 3.52Å; T51-L53 HydrophobicContact CG2-CG 3.69Å; T51-F113 HydrophobicContact CG2-CD1 3.89Å; T51-F113 HydrophobicContact CG2-CE1 3.69Å; T51-H149 PolarHBondContact OG1-NE2 3.33Å
52F98.6Very high96.1Very high0 Ų033 Ų330%020%0.202CC..EExtended strand (participates in β ladder)trans-126.1111.6171.4-58.3-96.1000108.8C27 V29 I36 R50 I55 C83 N111 V112 F202C27-F52 WeakPolarHBondContact O-CE1 3.19Å; C27-F52 WeakPolarHBondContact SG-CZ 3.42Å; V29-F52 HydrophobicContact CB-CE1 4.13Å; V29-F52 HydrophobicContact CB-CZ 4.12Å; V29-F52 HydrophobicContact CG2-CE1 3.82Å; V29-F52 HydrophobicContact CG2-CE2 4.03Å; V29-F52 HydrophobicContact CG2-CZ 3.32Å; I36-F52 HydrophobicContact CD1-CB 4.29Å; I36-F52 HydrophobicContact CD1-CD1 3.46Å; I36-F52 VanDerWaalsContact CD1-CD1 3.46Å; I36-F52 HydrophobicContact CD1-CE1 4.02Å; I36-F52 HydrophobicContact CD1-CG 4.02Å; I36-F52 HydrophobicContact CG1-CD1 3.88Å; I36-F52 HydrophobicContact CG1-CE1 4.05Å; R50-F52 HydrophobicContact CB-CE2 3.77Å; R50-F52 HydrophobicContact CB-CZ 4.42Å; F52-I55 HydrophobicContact CB-CD1 3.6Å; F52-I55 HydrophobicContact CB-CG1 4.06Å; F52-I55 HydrophobicContact CG-CD1 4.48Å; F52-C83 HydrophobicContact CB-CB 4.38Å; F52-N111 CarbonylContact O-C 3.58Å; F52-N111 WeakPolarHBondContact O-CA 3.48Å; F52-V112 PolarHBondContact N-O 3.14Å; F52-V112 PolarHBondContact O-N 2.95Å; F52-F202 HydrophobicContact CB-CE1 4.37Å; F52-F202 HydrophobicContact CD1-CE1 4.29Å; F52-F202 AromaticContact CD2-CD1 3.78Å; F52-F202 HydrophobicContact CD2-CD1 3.78Å; F52-F202 AromaticContact CD2-CE1 3.58Å; F52-F202 HydrophobicContact CD2-CE1 3.58Å; F52-F202 AromaticContact CE2-CD1 3.8Å; F52-F202 HydrophobicContact CE2-CD1 3.8Å; F52-F202 AromaticContact CE2-CE1 3.88Å; F52-F202 HydrophobicContact CE2-CE1 3.88Å; F52-F202 HydrophobicContact CG-CD1 4.48Å; F52-F202 AromaticContact CG-CE1 3.83Å; F52-F202 HydrophobicContact CG-CE1 3.83Å; F52-F202 HydrophobicContact CZ-CE1 4.36Å
53L98.1Very high96.2Very high9 Ų931.5 Ų31.55%0.04720%0.2CC..EExtended strand (participates in β ladder)trans-107130.5-178.1-54.5-177.8000110.2T51 C83 I85 Y86 N111 F113 P145T51-L53 HydrophobicContact CG2-CD1 4.3Å; T51-L53 HydrophobicContact CG2-CD2 3.52Å; T51-L53 HydrophobicContact CG2-CG 3.69Å; L53-C83 PolarHBondContact N-O 3.28Å; L53-C83 CarbonylContact O-C 3.58Å; L53-C83 WeakPolarHBondContact O-CA 3.29Å; L53-C83 VanDerWaalsContact O-CB 3.28Å; L53-C83 WeakPolarHBondContact O-CB 3.01Å; L53-I85 CarbonylContact C-O 3.53Å; L53-I85 WeakPolarHBondContact CB-O 3.26Å; L53-Y86 HydrophobicContact CD1-CD2 3.84Å; L53-Y86 HydrophobicContact CD1-CE2 4Å; L53-Y86 HydrophobicContact CD1-CG 4.23Å; L53-Y86 HydrophobicContact CD2-CD1 4.26Å; L53-Y86 HydrophobicContact CD2-CD2 4.47Å; L53-Y86 HydrophobicContact CD2-CE1 3.91Å; L53-Y86 HydrophobicContact CD2-CE2 4.11Å; L53-N111 WeakPolarHBondContact CA-OD1 3.39Å; L53-N111 HydrophobicContact CD2-CB 3.86Å; L53-F113 HydrophobicContact CD2-CE1 3.71Å; L53-F113 HydrophobicContact CD2-CZ 3.6Å; L53-P145 HydrophobicContact CD1-CG 4.44Å
54G97.8Very high96.4Very high0 Ų035.5 Ų35.50%023%0.228CC..EExtended strand (participates in β ladder)trans79.841.817400000114.9K87 Y109 L110 N111G54-K87 VanDerWaalsContact CA-CG 3.48Å; G54-Y109 VanDerWaalsContact O-CD1 3.27Å; G54-Y109 WeakPolarHBondContact O-CD1 3.42Å; G54-L110 PolarHBondContact N-O 3.45Å; G54-N111 PolarHBondContact N-OD1 3.2Å
55I98.7Very high96.7Very high0 Ų030.2 Ų30.20%020%0.199CC..EExtended strand (participates in β ladder)trans-79.4120.3173.6-55.7161.2000108.8L31 I36 F52 Y57 C83 Y109 L110 V112 W194 F202L31-I55 HydrophobicContact CD1-CG2 4.29Å; I36-I55 HydrophobicContact CD1-CD1 3.74Å; I36-I55 HydrophobicContact CD1-CG1 3.87Å; F52-I55 HydrophobicContact CB-CD1 3.6Å; F52-I55 HydrophobicContact CB-CG1 4.06Å; F52-I55 HydrophobicContact CG-CD1 4.48Å; I55-Y57 PolarHBondContact O-N 3.38Å; I55-C83 HydrophobicContact CG1-CB 4.37Å; I55-Y109 CarbonylContact O-C 3.54Å; I55-Y109 VanDerWaalsContact O-CA 3.28Å; I55-Y109 WeakPolarHBondContact O-CA 3.14Å; I55-L110 HydrophobicContact CB-CD1 3.97Å; I55-L110 HydrophobicContact CD1-CD1 3.97Å; I55-L110 PolarHBondContact N-O 3.25Å; I55-L110 PolarHBondContact O-N 3.04Å; I55-V112 HydrophobicContact CD1-CB 4.31Å; I55-V112 HydrophobicContact CD1-CG2 3.8Å; I55-W194 HydrophobicContact CD1-CH2 4.19Å; I55-W194 HydrophobicContact CG2-CH2 4.04Å; I55-W194 HydrophobicContact CG2-CZ2 3.47Å; I55-W194 VanDerWaalsContact CG2-CZ2 3.47Å; I55-F202 HydrophobicContact CD1-CE1 4.19Å; I55-F202 HydrophobicContact CD1-CZ 3.93Å
56P98.5Very high97.1Very high7 Ų727.8 Ų27.85%0.04517%0.167CC..EExtended strand (participates in β ladder)trans-74121.1178.928.5-32.2000109.9K73 W76 L81 Y109P56-K73 HydrophobicContact CB-CD 3.97Å; P56-K73 HydrophobicContact CB-CG 4.09Å; P56-K73 HydrophobicContact CG-CD 4.32Å; P56-K73 HydrophobicContact CG-CG 4.15Å; P56-W76 HydrophobicContact CG-CZ3 4.23Å; P56-L81 HydrophobicContact CG-CD2 3.54Å; P56-Y109 HydrophobicContact CB-CD1 3.85Å; P56-Y109 HydrophobicContact CB-CE1 3.7Å; P56-Y109 HydrophobicContact CG-CE1 4.33Å
57Y98.6Very high97.4Very high0 Ų024.2 Ų24.20%014%0.143CC..  trans-96.1-22.7174.665.3-98.5000112.2I55 K73 L108 L110 V162 A163 D187 E190 A191I55-Y57 PolarHBondContact O-N 3.38Å; Y57-K73 PolarHBondContact O-N 2.83Å; Y57-L108 WeakPolarHBondContact CD1-O 3.43Å; Y57-L108 HydrophobicContact CE1-CB 4.13Å; Y57-L108 WeakPolarHBondContact CE1-O 3.32Å; Y57-L108 HydrophobicContact CE2-CB 4.11Å; Y57-L108 PolarHBondContact N-O 3.31Å; Y57-L108 WeakPolarHBondContact OH-CD2 3.41Å; Y57-L110 HydrophobicContact CD1-CB 4.08Å; Y57-L110 HydrophobicContact CD1-CD2 3.89Å; Y57-L110 HydrophobicContact CD1-CG 4.01Å; Y57-L110 HydrophobicContact CG-CD2 4.13Å; Y57-V162 HydrophobicContact CE1-CG1 4.18Å; Y57-A163 PolarHBondContact OH-O 3.36Å; Y57-D187 VanDerWaalsContact CE2-O 3.27Å; Y57-D187 WeakPolarHBondContact CE2-O 3.1Å; Y57-E190 HydrophobicContact CD2-CB 4.36Å; Y57-E190 HydrophobicContact CD2-CG 4.1Å; Y57-E190 HydrophobicContact CE2-CB 4.36Å; Y57-E190 HydrophobicContact CE2-CG 4.48Å; Y57-A191 HydrophobicContact CD1-CB 4.13Å; Y57-A191 HydrophobicContact CD2-CB 3.96Å; Y57-A191 HydrophobicContact CE1-CB 4.11Å; Y57-A191 HydrophobicContact CE2-CB 3.96Å; Y57-A191 HydrophobicContact CG-CB 4.04Å
58A98.8Very high97.5Very high3 Ų322.4 Ų22.43%0.02513%0.134CC..BIsolated β-bridgetrans-133.4165.9177.400000111.8P70 K71 L108 E190A58-P70 HydrophobicContact CB-CB 3.93Å; A58-K71 CarbonylContact C-O 3.48Å; A58-K71 WeakPolarHBondContact CA-O 3.28Å; A58-K71 VanDerWaalsContact CB-O 3.31Å; A58-K71 WeakPolarHBondContact CB-O 3.42Å; A58-L108 HydrophobicContact CB-CB 4.03Å; A58-L108 HydrophobicContact CB-CD1 3.72Å; A58-E190 HydrophobicContact CB-CG 4.32Å
59E98.6Very high97.5Very high33 Ų3327.1 Ų27.115%0.15416%0.155CC..  trans-65.3149167.3-69.5-56.2148.900111.3L65 K71 K73 E74E59-L65 HydrophobicContact CB-CD1 3.89Å; E59-K71 HydrophobicContact CB-CB 4.37Å; E59-K71 HydrophobicContact CG-CB 4.38Å; E59-K71 HydrophobicContact CG-CD 4.3Å; E59-K71 HydrophobicContact CG-CG 4.41Å; E59-K71 PolarHBondContact N-O 3.45Å; E59-K73 WeakPolarHBondContact OE1-CD 3.45Å; E59-K73 IonicContact OE1-NZ 2.72Å; E59-K73 PolarHBondContact OE1-NZ 2.76Å; E59-K73 IonicContact OE2-NZ 2.81Å; E59-K73 PolarHBondContact OE2-NZ 2.85Å; E59-E74 WeakPolarHBondContact OE1-CB 3.04Å; E59-E74 PolarHBondContact OE1-N 2.92Å
60P98.5Very high97.7Very high31 Ų3128.1 Ų28.120%0.20116%0.161CC..  trans-55.2128.4175.1-24.334000110.8L62 D106P60-L62 HydrophobicContact CB-CD1 3.81Å; P60-L62 HydrophobicContact CB-CG 3.86Å; P60-L62 PolarHBondContact O-N 3.22Å; P60-D106 HydrophobicContact CB-CB 4.04Å
61P98Very high97.7Very high4 Ų430.4 Ų30.43%0.02617%0.173CC..  trans-79.154.2-17733.7-36.8000111.3R66 E105 L108 R165P61-R66 WeakPolarHBondContact O-CA 3.34Å; P61-R66 PolarHBondContact O-N 3.16Å; P61-E105 VanDerWaalsContact CD-O 3.3Å; P61-E105 WeakPolarHBondContact CD-O 3.47Å; P61-E105 VanDerWaalsContact CG-O 3.24Å; P61-E105 WeakPolarHBondContact CG-O 3.29Å; P61-L108 HydrophobicContact CB-CD1 4.18Å; P61-L108 HydrophobicContact CG-CD1 3.9Å; P61-L108 HydrophobicContact CG-CD2 4.49Å; P61-L108 HydrophobicContact CG-CG 3.96Å; P61-R165 HydrophobicContact CG-CG 4.24Å
62L97.5Very high97.7Very high79 Ų7933 Ų3341%0.41419%0.191SC..  trans-103.7154.5-175.2-59.8176.4000111.1P60 L65 E105 D106P60-L62 HydrophobicContact CB-CD1 3.81Å; P60-L62 HydrophobicContact CB-CG 3.86Å; P60-L62 PolarHBondContact O-N 3.22Å; L62-L65 PolarHBondContact O-N 2.85Å; L62-E105 HydrophobicContact CD2-CB 3.56Å; L62-D106 HydrophobicContact CD1-CB 4.49Å
63G95.4Very high97.7Very high39 Ų3935.6 Ų35.640%0.40220%0.202SC..G310 helixtrans55.7-121.7176.300000111.6L65 R66G63-L65 PolarHBondContact O-N 3.44Å; G63-R66 WeakPolarHBondContact O-CB 3.32Å; G63-R66 PolarHBondContact O-N 3.17Å
64P95.3Very high97.6Very high102 Ų10240.6 Ų40.666%0.66223%0.225SC*.G310 helixtrans-60.5-23.8177.9-22.933.8000114.7R66 R285P64-R66 VanDerWaalsContact C-N 3.32Å; P64-R285 PolarHBondContact O-NE 2.79Å
65L97.4Very high97.5Very high51 Ų5143.8 Ų43.827%0.26725%0.247SC..G310 helixtrans-83.9-7.7177.7-64.6179.8000113.1E59 L62 G63 A68 K71E59-L65 HydrophobicContact CB-CD1 3.89Å; L62-L65 PolarHBondContact O-N 2.85Å; G63-L65 PolarHBondContact O-N 3.44Å; L65-A68 PolarHBondContact O-N 2.95Å; L65-K71 HydrophobicContact CD2-CB 4.48Å
66R97.6Very high97.3Very high20 Ų2045.8 Ų45.88%0.07526%0.255CS..THydrogen-bonded Turntrans-68.3135.3168.5-170.6-173.2-68.7171.4-4.3108.6P61 G63 P64 A68 E105 R285 I287P61-R66 WeakPolarHBondContact O-CA 3.34Å; P61-R66 PolarHBondContact O-N 3.16Å; G63-R66 WeakPolarHBondContact O-CB 3.32Å; G63-R66 PolarHBondContact O-N 3.17Å; P64-R66 VanDerWaalsContact C-N 3.32Å; R66-A68 PolarHBondContact O-N 2.94Å; R66-E105 IonicContact CZ-OE1 2.86Å; R66-E105 IonicContact CZ-OE2 3.22Å; R66-E105 IonicContact NE-OE1 3.77Å; R66-E105 PolarHBondContact NE-OE1 2.89Å; R66-E105 IonicContact NE-OE2 3.37Å; R66-E105 IonicContact NH2-OE1 3.93Å; R66-E105 PolarHBondContact NH2-OE1 3.09Å; R66-E105 IonicContact NH2-OE2 2.71Å; R66-E105 PolarHBondContact NH2-OE2 3.27Å; R66-R285 HydrophobicContact CB-CG 4.31Å; R66-R285 PolarHBondContact NH1-O 3.04Å; R66-R285 PolarHBondContact O-NE 2.79Å; R66-R285 PolarHBondContact O-NH2 3.46Å; R66-I287 PolarHBondContact NH1-O 3.42Å
67F96.7Very high96.8Very high1 Ų153.3 Ų53.30%0.00429%0.287CS..THydrogen-bonded Turntrans54.138.1-173.3-43.7-51000113.5V168 F172 A179 F183 M284 R285 L292F67-V168 HydrophobicContact CE1-CG2 4.44Å; F67-V168 WeakPolarHBondContact CE1-O 3.22Å; F67-F172 HydrophobicContact CB-CD1 4.13Å; F67-F172 HydrophobicContact CD1-CB 3.65Å; F67-F172 AromaticContact CD1-CD1 3.78Å; F67-F172 HydrophobicContact CD1-CD1 3.78Å; F67-F172 HydrophobicContact CD1-CG 4.07Å; F67-F172 AromaticContact CD2-CD1 3.84Å; F67-F172 HydrophobicContact CD2-CD1 3.84Å; F67-F172 HydrophobicContact CD2-CE1 4.23Å; F67-F172 HydrophobicContact CE1-CB 3.57Å; F67-F172 HydrophobicContact CE1-CD1 4.08Å; F67-F172 HydrophobicContact CE1-CG 4.02Å; F67-F172 HydrophobicContact CE2-CD1 4.15Å; F67-F172 HydrophobicContact CG-CB 4.4Å; F67-F172 AromaticContact CG-CD1 3.64Å; F67-F172 HydrophobicContact CG-CD1 3.64Å; F67-F172 HydrophobicContact CG-CE1 4.4Å; F67-F172 HydrophobicContact CG-CG 4.38Å; F67-F172 HydrophobicContact CZ-CB 4.27Å; F67-F172 HydrophobicContact CZ-CD1 4.24Å; F67-F172 HydrophobicContact CZ-CG 4.28Å; F67-A179 HydrophobicContact CB-CB 4.47Å; F67-F183 VanDerWaalsContact C-CE1 3.44Å; F67-F183 HydrophobicContact CB-CD2 4.45Å; F67-F183 HydrophobicContact CB-CE2 3.65Å; F67-F183 HydrophobicContact CB-CZ 3.94Å; F67-F183 HydrophobicContact CD1-CD2 4.46Å; F67-F183 HydrophobicContact CD1-CE2 4.19Å; F67-F183 HydrophobicContact CG-CE2 4.4Å; F67-F183 WeakPolarHBondContact O-CE1 3.39Å; F67-F183 WeakPolarHBondContact O-CZ 3.46Å; F67-M284 HydrophobicContact CD2-CB 4.33Å; F67-M284 HydrophobicContact CE2-CB 3.76Å; F67-R285 HydrophobicContact CD2-CG 4.07Å; F67-R285 PolarHBondContact O-NH2 3.28Å; F67-L292 HydrophobicContact CZ-CD2 3.74Å
68A96.3Very high96.2Very high23 Ų2360.8 Ų60.819%0.1933%0.327CS..SBendtrans-130163.4169.100000109.4L65 R66 R165 F183L65-A68 PolarHBondContact O-N 2.95Å; R66-A68 PolarHBondContact O-N 2.94Å; A68-R165 PolarHBondContact O-NH1 2.52Å; A68-R165 PolarHBondContact O-NH2 3.13Å; A68-F183 VanDerWaalsContact C-CD1 3.46Å; A68-F183 WeakPolarHBondContact O-CD1 3.47Å
69E96.7Very high95.8Very high117 Ų11763.4 Ų63.455%0.54735%0.349SS..PPolyproline II helixtrans-55.4145.3169.1-65.6-164.8140.300111K71E69-K71 PolarHBondContact O-N 2.95Å
70P98.5Very high95.6Very high20 Ų2065.5 Ų65.513%0.1336%0.363CS..PPolyproline II helixtrans-62136174.929.4-36.4000110.1A58 L108 S186 D187 E190A58-P70 HydrophobicContact CB-CB 3.93Å; P70-L108 HydrophobicContact CB-CD1 4.12Å; P70-S186 VanDerWaalsContact CD-CB 3.43Å; P70-S186 WeakPolarHBondContact CG-O 3.3Å; P70-D187 WeakPolarHBondContact CB-OD1 3.14Å; P70-E190 HydrophobicContact CB-CB 4.21Å; P70-E190 HydrophobicContact CB-CG 4.29Å; P70-E190 HydrophobicContact CG-CB 3.67Å; P70-E190 HydrophobicContact CG-CG 4.2Å
71K98.5Very high95.5Very high99 Ų9966.6 Ų66.643%0.4337%0.367SS..PPolyproline II helixtrans-92.7130.3169.9-176.4-177.4169.7-165.90108.6A58 E59 L65 E69 E74A58-K71 CarbonylContact C-O 3.48Å; A58-K71 WeakPolarHBondContact CA-O 3.28Å; A58-K71 VanDerWaalsContact CB-O 3.31Å; A58-K71 WeakPolarHBondContact CB-O 3.42Å; E59-K71 HydrophobicContact CB-CB 4.37Å; E59-K71 HydrophobicContact CG-CB 4.38Å; E59-K71 HydrophobicContact CG-CD 4.3Å; E59-K71 HydrophobicContact CG-CG 4.41Å; E59-K71 PolarHBondContact N-O 3.45Å; L65-K71 HydrophobicContact CD2-CB 4.48Å; E69-K71 PolarHBondContact O-N 2.95Å; K71-E74 IonicContact NZ-OE1 3.61Å; K71-E74 PolarHBondContact NZ-OE1 2.88Å
72S98.5Very high95.5Very high56 Ų5669.5 Ų69.539%0.39239%0.388SS..BIsolated β-bridgetrans-51.2141174.5-51.70000111.6E74 E190S72-E74 PolarHBondContact O-N 2.89Å; S72-E190 WeakPolarHBondContact CA-OE1 3.4Å; S72-E190 VanDerWaalsContact CB-OE1 3.24Å; S72-E190 WeakPolarHBondContact CB-OE1 3.31Å; S72-E190 PolarHBondContact OG-OE1 3.27Å
73K97.8Very high95.5Very high54 Ų5465.7 Ų65.724%0.23537%0.368CS..PPolyproline II helixtrans-62.8129-177.8-173.167.7-164.2166.80111.6P56 Y57 E59 W76P56-K73 HydrophobicContact CB-CD 3.97Å; P56-K73 HydrophobicContact CB-CG 4.09Å; P56-K73 HydrophobicContact CG-CD 4.32Å; P56-K73 HydrophobicContact CG-CG 4.15Å; Y57-K73 PolarHBondContact O-N 2.83Å; E59-K73 WeakPolarHBondContact OE1-CD 3.45Å; E59-K73 IonicContact OE1-NZ 2.72Å; E59-K73 PolarHBondContact OE1-NZ 2.76Å; E59-K73 IonicContact OE2-NZ 2.81Å; E59-K73 PolarHBondContact OE2-NZ 2.85Å; K73-W76 HydrophobicContact CG-CE3 4.42Å; K73-W76 HydrophobicContact CG-CZ3 4.17Å
74E95.8Very high95.5Very high113 Ų11366.7 Ų66.753%0.52836%0.362SS..PPolyproline II helixtrans-69.8152.5174.2-69.3-173.7-179.400111.7E59 K71 S72 W76E59-E74 WeakPolarHBondContact OE1-CB 3.04Å; E59-E74 PolarHBondContact OE1-N 2.92Å; K71-E74 IonicContact NZ-OE1 3.61Å; K71-E74 PolarHBondContact NZ-OE1 2.88Å; S72-E74 PolarHBondContact O-N 2.89Å; E74-W76 PolarHBondContact O-N 3.5Å
75S95.4Very high95.5Very high67 Ų6766.3 Ų66.347%0.46935%0.354SS..PPolyproline II helixtrans-63.1131.2178.3175.60000111.3T33 K77T33-S75 CarbonylContact O-C 3.57Å; T33-S75 WeakPolarHBondContact O-CA 3.31Å; T33-S75 VanDerWaalsContact O-CB 3.26Å; T33-S75 WeakPolarHBondContact O-CB 3.47Å; T33-S75 PolarHBondContact O-OG 3.24Å; S75-K77 PolarHBondContact O-N 3.29Å; S75-K77 PolarHBondContact OG-N 2.9Å
76W94.2Very high95.4Very high42 Ų4265.7 Ų65.716%0.15935%0.348CS..  trans-89.518.8169.558.885.7000112.6L31 T33 K35 I36 P56 K73 E74 D78 A79 L81L31-W76 HydrophobicContact CD1-CH2 4.08Å; L31-W76 HydrophobicContact CD1-CZ2 4.36Å; T33-W76 PolarHBondContact O-N 3.32Å; T33-W76 WeakPolarHBondContact OG1-CH2 3.42Å; T33-W76 WeakPolarHBondContact OG1-CZ3 3.37Å; K35-W76 PolarHBondContact O-NE1 3.16Å; I36-W76 HydrophobicContact CG2-CH2 3.99Å; I36-W76 HydrophobicContact CG2-CZ2 3.49Å; I36-W76 VanDerWaalsContact CG2-CZ2 3.49Å; P56-W76 HydrophobicContact CG-CZ3 4.23Å; K73-W76 HydrophobicContact CG-CE3 4.42Å; K73-W76 HydrophobicContact CG-CZ3 4.17Å; E74-W76 PolarHBondContact O-N 3.5Å; W76-D78 PolarHBondContact O-N 3.43Å; W76-A79 PolarHBondContact NE1-O 3.26Å; W76-A79 WeakPolarHBondContact O-CB 3.48Å; W76-A79 PolarHBondContact O-N 2.77Å; W76-A79 VanDerWaalsContact O-N 3.16Å; W76-L81 HydrophobicContact CH2-CD2 4.35Å; W76-L81 HydrophobicContact CZ2-CB 4.24Å; W76-L81 HydrophobicContact CZ2-CD2 4.4Å; W76-L81 HydrophobicContact CZ3-CD2 4.49Å
77K88Confident95.3Very high165 Ų16568 Ų6872%0.71736%0.358SS*.THydrogen-bonded Turntrans52-120.4173.5-56.7179.8-178.2178.20112.2S75S75-K77 PolarHBondContact O-N 3.29Å; S75-K77 PolarHBondContact OG-N 2.9Å
78D86.2Confident95.2Very high158 Ų15869.3 Ų69.385%0.84537%0.367SS*.THydrogen-bonded Turntrans-86.6-5.4-173.7-58.1-52.7000113.6W76W76-D78 PolarHBondContact O-N 3.43Å
79A91.2Very high95.1Very high57 Ų5768.2 Ų68.247%0.47136%0.358SS..  trans-67.2149176.300000111W76W76-A79 PolarHBondContact NE1-O 3.26Å; W76-A79 WeakPolarHBondContact O-CB 3.48Å; W76-A79 PolarHBondContact O-N 2.77Å; W76-A79 VanDerWaalsContact O-N 3.16Å
80V94.9Very high95Very high77 Ų7762.9 Ų62.947%0.46733%0.333SS..EExtended strand (participates in β ladder)trans-101.1116169.3-175.70000107.4K35 E37K35-V80 HydrophobicContact CB-CG1 4.39Å; K35-V80 HydrophobicContact CB-CG2 4.06Å; K35-V80 HydrophobicContact CD-CG2 4.34Å; K35-V80 WeakPolarHBondContact O-CA 3.44Å; E37-V80 HydrophobicContact CB-CG1 3.75Å
81L96.6Very high94.8Very high54 Ų5464.6 Ų64.628%0.28334%0.337SS..EExtended strand (participates in β ladder)trans-82.8129.3179.3-175.567.1000110.2K35 I36 E37 P56 W76 C83K35-L81 PolarHBondContact O-N 2.97Å; I36-L81 CarbonylContact C-O 3.58Å; I36-L81 WeakPolarHBondContact CA-O 3.36Å; I36-L81 HydrophobicContact CG2-CB 4.26Å; E37-L81 PolarHBondContact N-O 3.2Å; P56-L81 HydrophobicContact CG-CD2 3.54Å; W76-L81 HydrophobicContact CH2-CD2 4.35Å; W76-L81 HydrophobicContact CZ2-CB 4.24Å; W76-L81 HydrophobicContact CZ2-CD2 4.4Å; W76-L81 HydrophobicContact CZ3-CD2 4.49Å; L81-C83 PolarHBondContact O-N 3.26Å
82S96.4Very high94.5Very high65 Ų6560.2 Ų60.246%0.45532%0.318SS..EExtended strand (participates in β ladder)trans-79.7118.7178.7-170.10000111.7H84S82-H84 PolarHBondContact OG-CD2 3.02Å
83C97.5Very high93.3Very high0 Ų062.2 Ų62.20%033%0.325CS..  trans-122.447.5-177.4-66.70000111.5E37 F52 L53 I55 L81E37-C83 CarbonylContact O-C 3.55Å; E37-C83 WeakPolarHBondContact O-CA 3.37Å; E37-C83 WeakPolarHBondContact O-CB 2.89Å; E37-C83 PolarHBondContact O-N 2.83Å; F52-C83 HydrophobicContact CB-CB 4.38Å; L53-C83 PolarHBondContact N-O 3.28Å; L53-C83 CarbonylContact O-C 3.58Å; L53-C83 WeakPolarHBondContact O-CA 3.29Å; L53-C83 VanDerWaalsContact O-CB 3.28Å; L53-C83 WeakPolarHBondContact O-CB 3.01Å; I55-C83 HydrophobicContact CG1-CB 4.37Å; L81-C83 PolarHBondContact O-N 3.26Å
84H95.7Very high91.7Very high59 Ų5962.7 Ų62.727%0.27333%0.325SS..BIsolated β-bridgetrans-93.1-18.9-178.1-65.9-63.9000114.8E37 G38 H39 S82E37-H84 IonicContact OE2-CD2 3.93Å; E37-H84 IonicContact OE2-CE1 3.72Å; E37-H84 IonicContact OE2-NE2 2.87Å; E37-H84 PolarHBondContact OE2-NE2 3.2Å; G38-H84 VanDerWaalsContact C-CE1 3.46Å; G38-H84 PolarHBondContact O-CE1 3.31Å; H39-H84 AromaticContact ND1-ND1 3.74Å; S82-H84 PolarHBondContact OG-CD2 3.02Å
85I95.1Very high89.6Confident95 Ų9559 Ų5949%0.48731%0.312SS..SBendtrans-132.6145.8-173.661.5171.2000111.3L53 K87L53-I85 CarbonylContact C-O 3.53Å; L53-I85 WeakPolarHBondContact CB-O 3.26Å; I85-K87 PolarHBondContact O-N 3.24Å
86Y95.7Very high87.4Confident37 Ų3763.9 Ų63.915%0.14532%0.32CS..PPolyproline II helixtrans-55.2140.2169.1-77.9-72.7000110.8L53 N111 F113 P140 F143 P145L53-Y86 HydrophobicContact CD1-CD2 3.84Å; L53-Y86 HydrophobicContact CD1-CE2 4Å; L53-Y86 HydrophobicContact CD1-CG 4.23Å; L53-Y86 HydrophobicContact CD2-CD1 4.26Å; L53-Y86 HydrophobicContact CD2-CD2 4.47Å; L53-Y86 HydrophobicContact CD2-CE1 3.91Å; L53-Y86 HydrophobicContact CD2-CE2 4.11Å; Y86-N111 VanDerWaalsContact CD1-OD1 3.32Å; Y86-N111 WeakPolarHBondContact CD1-OD1 3.27Å; Y86-N111 HydrophobicContact CE1-CB 4.11Å; Y86-N111 VanDerWaalsContact CE1-CG 3.43Å; Y86-N111 WeakPolarHBondContact CE1-ND2 3.32Å; Y86-F113 HydrophobicContact CE1-CZ 4.45Å; Y86-F113 VanDerWaalsContact OH-CZ 3.29Å; Y86-F113 WeakPolarHBondContact OH-CZ 3.16Å; Y86-P140 HydrophobicContact CE1-CB 4.4Å; Y86-F143 PolarHBondContact OH-O 2.84Å; Y86-P145 HydrophobicContact CE2-CG 3.73Å
87K95.5Very high85.4Confident68 Ų6868.5 Ų68.530%0.29634%0.337SS..PPolyproline II helixtrans-83.8163.1173.2-67.1-73-178.7-177.50110.5G54 I85 Y109G54-K87 VanDerWaalsContact CA-CG 3.48Å; I85-K87 PolarHBondContact O-N 3.24Å; K87-Y109 HydrophobicContact CB-CD1 4.28Å; K87-Y109 HydrophobicContact CB-CD2 3.54Å; K87-Y109 HydrophobicContact CB-CE2 4Å; K87-Y109 HydrophobicContact CB-CG 3.72Å; K87-Y109 HydrophobicContact CD-CD1 4.38Å; K87-Y109 HydrophobicContact CD-CE1 4.11Å; K87-Y109 HydrophobicContact CD-CE2 4.43Å; K87-Y109 HydrophobicContact CG-CD1 3.67Å; K87-Y109 HydrophobicContact CG-CD2 3.84Å; K87-Y109 HydrophobicContact CG-CE1 3.9Å; K87-Y109 HydrophobicContact CG-CE2 4.12Å; K87-Y109 HydrophobicContact CG-CG 3.65Å
88P94.4Very high83.8Confident29 Ų2964 Ų6419%0.18832%0.324CS..PPolyproline II helixtrans-53.4145.5178.7-26.136000112R102P88-R102 WeakPolarHBondContact CA-O 3.43Å; P88-R102 HydrophobicContact CB-CB 4.02Å; P88-R102 HydrophobicContact CG-CB 4.15Å
89A94.3Very high82.3Confident0 Ų065.2 Ų65.20%032%0.322CS..EExtended strand (participates in β ladder)trans-62.8154.1168.700000110.4P100 R102 I103 S104 S139A89-P100 HydrophobicContact CB-CB 3.65Å; A89-P100 HydrophobicContact CB-CG 4.14Å; A89-R102 PolarHBondContact N-O 2.04Å; A89-I103 HydrophobicContact CB-CG2 4.32Å; A89-I103 CarbonylContact O-C 3.53Å; A89-I103 VanDerWaalsContact O-CA 3.29Å; A89-I103 WeakPolarHBondContact O-CA 3.5Å; A89-S104 PolarHBondContact O-N 3.39Å; A89-S139 VanDerWaalsContact CB-CB 3.46Å; A89-S139 WeakPolarHBondContact CB-OG 3.38Å
90C95.8Very high80.7Confident5 Ų563.8 Ų63.83%0.03431%0.307CS..EExtended strand (participates in β ladder)trans-60.7147.1170.3-66.50000111.1Q92 S104 C107 Y164 L166C90-Q92 WeakPolarHBondContact O-CG 3.48Å; C90-Q92 PolarHBondContact O-N 2.91Å; C90-Q92 PolarHBondContact O-NE2 3.45Å; C90-S104 CarbonylContact C-O 3.54Å; C90-S104 WeakPolarHBondContact CA-O 3.39Å; C90-C107 VanDerWaalsContact CA-CB 3.46Å; C90-C107 WeakPolarHBondContact CA-SG 3.39Å; C90-C107 HydrophobicContact CB-CB 3.8Å; C90-C107 WeakPolarHBondContact CB-SG 3.2Å; C90-C107 WeakPolarHBondContact SG-CB 3.35Å; C90-C107 CovalentContact SG-SG 2.03Å; C90-C107 PolarHBondContact SG-SG 3.21Å; C90-Y164 PolarHBondContact SG-O 2.93Å; C90-L166 HydrophobicContact CB-CD1 4.29Å; C90-L166 HydrophobicContact CB-CG 4.3Å
91W94.2Very high79.3Confident56 Ų5664.9 Ų64.921%0.21233%0.325CS..SBendtrans-52126.1-172.6-164.6-71.4000112.4I103 S104 E105 F169 A289 D290 D293W91-I103 HydrophobicContact CD2-CD1 4.38Å; W91-S104 PolarHBondContact N-O 3.1Å; W91-S104 VanDerWaalsContact N-O 3.09Å; W91-E105 HydrophobicContact CB-CG 4.18Å; W91-E105 HydrophobicContact CE3-CG 4.15Å; W91-F169 HydrophobicContact CB-CD2 3.96Å; W91-F169 HydrophobicContact CB-CE2 3.8Å; W91-F169 HydrophobicContact CB-CZ 4.21Å; W91-F169 AromaticContact CD1-CE2 3.34Å; W91-F169 AromaticContact CD1-CZ 3.75Å; W91-F169 HydrophobicContact CD2-CZ 4.47Å; W91-F169 HydrophobicContact CG-CD2 4.32Å; W91-F169 AromaticContact CG-CE2 3.66Å; W91-F169 HydrophobicContact CG-CE2 3.66Å; W91-F169 AromaticContact CG-CZ 3.86Å; W91-F169 HydrophobicContact CG-CZ 3.86Å; W91-A289 HydrophobicContact CD2-CB 3.59Å; W91-A289 HydrophobicContact CE3-CB 3.59Å; W91-A289 HydrophobicContact CG-CB 4.31Å; W91-A289 HydrophobicContact CH2-CB 3.82Å; W91-A289 HydrophobicContact CZ2-CB 3.84Å; W91-A289 HydrophobicContact CZ3-CB 3.7Å; W91-A289 PolarHBondContact NE1-O 2.95Å; W91-D290 HydrophobicContact CH2-CB 4.22Å; W91-D290 VanDerWaalsContact CZ2-CA 3.46Å; W91-D290 HydrophobicContact CZ2-CB 3.71Å; W91-D290 VanDerWaalsContact CZ2-N 3.27Å; W91-D293 PolarHBondContact NE1-OD2 2.95Å
92Q90.4Very high78.9Confident7 Ų769.3 Ų69.33%0.03334%0.338CS..  trans-162.1139.9-178.262.7-169.6-91.300110.5C90 R94 P100 I103 D136 D138C90-Q92 WeakPolarHBondContact O-CG 3.48Å; C90-Q92 PolarHBondContact O-N 2.91Å; C90-Q92 PolarHBondContact O-NE2 3.45Å; Q92-R94 PolarHBondContact OE1-O 3.46Å; Q92-P100 HydrophobicContact CG-CG 4.35Å; Q92-I103 HydrophobicContact CG-CG2 4.12Å; Q92-I103 WeakPolarHBondContact O-CD1 3.29Å; Q92-D136 WeakPolarHBondContact CB-O 3.32Å; Q92-D138 PolarHBondContact NE2-O 3.41Å
93N74.5Confident78.7Confident99 Ų9969.2 Ų69.253%0.52933%0.331SS..SBendtrans-102.4-2173.7-166.44.1000113.4D293N93-D293 WeakPolarHBondContact CB-OD2 2.99Å; N93-D293 PolarHBondContact N-OD2 2.88Å
94R64.1Low78.6Confident63 Ų6370.9 Ų70.924%0.23834%0.343CS..  trans-104.4120.9176.1-77.2179.4148.6-165.30.4109.4Q92 F137 N301Q92-R94 PolarHBondContact OE1-O 3.46Å; R94-F137 HydrophobicContact CB-CB 4.36Å; R94-F137 HydrophobicContact CB-CD1 4.22Å; R94-F137 HydrophobicContact CB-CG 4.5Å; R94-F137 WeakPolarHBondContact O-CB 3.3Å; R94-N301 PolarHBondContact NH2-OD1 3.48Å
95S52.1Low78.7Confident35 Ų3569.1 Ų69.125%0.24534%0.335CS..  trans-133.5113.5154.279.50000109.1T98 K99S95-T98 WeakPolarHBondContact CB-O 3.3Å; S95-T98 PolarHBondContact OG-O 2.87Å; S95-K99 WeakPolarHBondContact OG-CA 3.4Å; S95-K99 WeakPolarHBondContact OG-CG 3.43Å; S95-K99 PolarHBondContact OG-N 3.22Å; S95-K99 VanDerWaalsContact OG-N 3.13Å
96R48.9Very low78.8Confident170 Ų17066.8 Ų66.864%0.64232%0.323SS*.SBendtrans-80.1-25175.4-87.1178166.2164.8-1.5113E134R96-E134 IonicContact NH1-OE1 3.53Å
97R52.9Low78.9Confident139 Ų13965.1 Ų65.153%0.52532%0.317SS..SBendtrans-112.2-47-166.9-61.5-174.4179.1-154.84.4113.1S488R97-S488 PolarHBondContact NH2-OG 3.42Å
98T53.5Low79Confident70 Ų7062 Ų6243%0.42930%0.303SS..  trans-151.1121.6178.145.70000108S95 P100S95-T98 WeakPolarHBondContact CB-O 3.3Å; S95-T98 PolarHBondContact OG-O 2.87Å; T98-P100 VanDerWaalsContact O-CD 3.27Å; T98-P100 WeakPolarHBondContact O-CD 3.43Å; T98-P100 VanDerWaalsContact O-N 3.08Å
99K54.9Low79.2Confident185 Ų18562 Ų6280%0.80430%0.3SS*.  trans-58.2118.3169.1-77.6-175.3177.4-172.60107S95 A101S95-K99 WeakPolarHBondContact OG-CA 3.4Å; S95-K99 WeakPolarHBondContact OG-CG 3.43Å; S95-K99 PolarHBondContact OG-N 3.22Å; S95-K99 VanDerWaalsContact OG-N 3.13Å; K99-A101 PolarHBondContact O-N 2.96Å
100P57Low79.5Confident26 Ų2662 Ų6217%0.16930%0.3CS..  trans-52.9134170.621.5-30.8000107.2A89 Q92 T98 R102 I103A89-P100 HydrophobicContact CB-CB 3.65Å; A89-P100 HydrophobicContact CB-CG 4.14Å; Q92-P100 HydrophobicContact CG-CG 4.35Å; T98-P100 VanDerWaalsContact O-CD 3.27Å; T98-P100 WeakPolarHBondContact O-CD 3.43Å; T98-P100 VanDerWaalsContact O-N 3.08Å; P100-R102 PolarHBondContact O-N 3.25Å; P100-R102 VanDerWaalsContact O-N 3.1Å; P100-I103 HydrophobicContact CB-CG2 4.21Å; P100-I103 HydrophobicContact CG-CG2 3.52Å
101A66.4Low79.6Confident101 Ų10161.9 Ų61.984%0.83530%0.299SS*.SBendtrans-58.2-31.1-172.900000111.7K99K99-A101 PolarHBondContact O-N 2.96Å
102R87.2Confident79.8Confident147 Ų14759.2 Ų59.256%0.55529%0.289SS*.  trans-145.1141.2176.6-70.8177.9-100.4157.2-3.2109.8P88 A89 P100P88-R102 WeakPolarHBondContact CA-O 3.43Å; P88-R102 HydrophobicContact CB-CB 4.02Å; P88-R102 HydrophobicContact CG-CB 4.15Å; A89-R102 PolarHBondContact N-O 2.04Å; P100-R102 PolarHBondContact O-N 3.25Å; P100-R102 VanDerWaalsContact O-N 3.1Å
103I92.4Very high80.2Confident63 Ų6358.9 Ų58.932%0.32329%0.287SS..EExtended strand (participates in β ladder)trans-120147.4170.762.5176000109.8A89 W91 Q92 P100A89-I103 HydrophobicContact CB-CG2 4.32Å; A89-I103 CarbonylContact O-C 3.53Å; A89-I103 VanDerWaalsContact O-CA 3.29Å; A89-I103 WeakPolarHBondContact O-CA 3.5Å; W91-I103 HydrophobicContact CD2-CD1 4.38Å; Q92-I103 HydrophobicContact CG-CG2 4.12Å; Q92-I103 WeakPolarHBondContact O-CD1 3.29Å; P100-I103 HydrophobicContact CB-CG2 4.21Å; P100-I103 HydrophobicContact CG-CG2 3.52Å
104S95.6Very high81.4Confident34 Ų3454.2 Ų54.224%0.23826%0.262CS..EExtended strand (participates in β ladder)trans-157.5159.5175.8-176.10000109.7A89 C90 W91 D106 C107A89-S104 PolarHBondContact O-N 3.39Å; C90-S104 CarbonylContact C-O 3.54Å; C90-S104 WeakPolarHBondContact CA-O 3.39Å; W91-S104 PolarHBondContact N-O 3.1Å; W91-S104 VanDerWaalsContact N-O 3.09Å; S104-D106 PolarHBondContact OG-N 2.66Å; S104-C107 WeakPolarHBondContact O-CB 3.27Å
105E97Very high82.9Confident23 Ų2351.2 Ų51.211%0.10725%0.251CS..SBendtrans-78.6-27.7164.3-69.5179.389.800112.3P61 L62 R66 W91 C107 F169 A289P61-E105 VanDerWaalsContact CD-O 3.3Å; P61-E105 WeakPolarHBondContact CD-O 3.47Å; P61-E105 VanDerWaalsContact CG-O 3.24Å; P61-E105 WeakPolarHBondContact CG-O 3.29Å; L62-E105 HydrophobicContact CD2-CB 3.56Å; R66-E105 IonicContact CZ-OE1 2.86Å; R66-E105 IonicContact CZ-OE2 3.22Å; R66-E105 IonicContact NE-OE1 3.77Å; R66-E105 PolarHBondContact NE-OE1 2.89Å; R66-E105 IonicContact NE-OE2 3.37Å; R66-E105 IonicContact NH2-OE1 3.93Å; R66-E105 PolarHBondContact NH2-OE1 3.09Å; R66-E105 IonicContact NH2-OE2 2.71Å; R66-E105 PolarHBondContact NH2-OE2 3.27Å; W91-E105 HydrophobicContact CB-CG 4.18Å; W91-E105 HydrophobicContact CE3-CG 4.15Å; E105-C107 PolarHBondContact O-N 3.16Å; E105-F169 HydrophobicContact CG-CD1 4.11Å; E105-F169 HydrophobicContact CG-CE1 4.02Å; E105-F169 WeakPolarHBondContact OE1-CD1 3.39Å; E105-F169 WeakPolarHBondContact OE1-CE1 3.48Å; E105-A289 HydrophobicContact CG-CB 4.15Å; E105-A289 WeakPolarHBondContact OE2-CB 3.2Å
106D97.8Very high84.9Confident46 Ų4653.3 Ų53.325%0.24626%0.26CS..  trans-72.984.3165-179.814.8000108.7P60 L62 S104 Y109P60-D106 HydrophobicContact CB-CB 4.04Å; L62-D106 HydrophobicContact CD1-CB 4.49Å; S104-D106 PolarHBondContact OG-N 2.66Å; D106-Y109 VanDerWaalsContact CG-OH 3.26Å; D106-Y109 VanDerWaalsContact OD1-CE2 3.22Å; D106-Y109 WeakPolarHBondContact OD1-CE2 3.41Å; D106-Y109 PolarHBondContact OD1-OH 2.99Å; D106-Y109 PolarHBondContact OD2-OH 2.91Å
107C97.8Very high87.1Confident1 Ų149.7 Ų49.71%0.00725%0.253CS..  trans-137.73.1-170.870.90000114.7C90 S104 E105 Y109 A163C90-C107 VanDerWaalsContact CA-CB 3.46Å; C90-C107 WeakPolarHBondContact CA-SG 3.39Å; C90-C107 HydrophobicContact CB-CB 3.8Å; C90-C107 WeakPolarHBondContact CB-SG 3.2Å; C90-C107 WeakPolarHBondContact SG-CB 3.35Å; C90-C107 CovalentContact SG-SG 2.03Å; C90-C107 PolarHBondContact SG-SG 3.21Å; S104-C107 WeakPolarHBondContact O-CB 3.27Å; E105-C107 PolarHBondContact O-N 3.16Å; C107-Y109 VanDerWaalsContact C-CD2 3.44Å; C107-Y109 PolarHBondContact O-N 3.18Å; C107-A163 VanDerWaalsContact O-CB 3.28Å; C107-A163 WeakPolarHBondContact O-CB 3.4Å
108L98.8Very high89.2Confident2 Ų243.1 Ų43.11%0.0123%0.229CC..  trans-79.567.5-177.3-56.6-172.2000111.9Y57 A58 P61 P70 R165 D187Y57-L108 WeakPolarHBondContact CD1-O 3.43Å; Y57-L108 HydrophobicContact CE1-CB 4.13Å; Y57-L108 WeakPolarHBondContact CE1-O 3.32Å; Y57-L108 HydrophobicContact CE2-CB 4.11Å; Y57-L108 PolarHBondContact N-O 3.31Å; Y57-L108 WeakPolarHBondContact OH-CD2 3.41Å; A58-L108 HydrophobicContact CB-CB 4.03Å; A58-L108 HydrophobicContact CB-CD1 3.72Å; P61-L108 HydrophobicContact CB-CD1 4.18Å; P61-L108 HydrophobicContact CG-CD1 3.9Å; P61-L108 HydrophobicContact CG-CD2 4.49Å; P61-L108 HydrophobicContact CG-CG 3.96Å; P70-L108 HydrophobicContact CB-CD1 4.12Å; L108-R165 HydrophobicContact CD2-CG 4.13Å; L108-D187 HydrophobicContact CD2-CB 4.12Å; L108-D187 WeakPolarHBondContact CD2-OD2 3.32Å
109Y98.7Very high91.2Very high29 Ų2942.1 Ų42.111%0.11422%0.222CC..EExtended strand (participates in β ladder)trans-123149.9-179.2-58.8-91.3000111.2G54 I55 P56 K87 D106 C107 A163G54-Y109 VanDerWaalsContact O-CD1 3.27Å; G54-Y109 WeakPolarHBondContact O-CD1 3.42Å; I55-Y109 CarbonylContact O-C 3.54Å; I55-Y109 VanDerWaalsContact O-CA 3.28Å; I55-Y109 WeakPolarHBondContact O-CA 3.14Å; P56-Y109 HydrophobicContact CB-CD1 3.85Å; P56-Y109 HydrophobicContact CB-CE1 3.7Å; P56-Y109 HydrophobicContact CG-CE1 4.33Å; K87-Y109 HydrophobicContact CB-CD1 4.28Å; K87-Y109 HydrophobicContact CB-CD2 3.54Å; K87-Y109 HydrophobicContact CB-CE2 4Å; K87-Y109 HydrophobicContact CB-CG 3.72Å; K87-Y109 HydrophobicContact CD-CD1 4.38Å; K87-Y109 HydrophobicContact CD-CE1 4.11Å; K87-Y109 HydrophobicContact CD-CE2 4.43Å; K87-Y109 HydrophobicContact CG-CD1 3.67Å; K87-Y109 HydrophobicContact CG-CD2 3.84Å; K87-Y109 HydrophobicContact CG-CE1 3.9Å; K87-Y109 HydrophobicContact CG-CE2 4.12Å; K87-Y109 HydrophobicContact CG-CG 3.65Å; D106-Y109 VanDerWaalsContact CG-OH 3.26Å; D106-Y109 VanDerWaalsContact OD1-CE2 3.22Å; D106-Y109 WeakPolarHBondContact OD1-CE2 3.41Å; D106-Y109 PolarHBondContact OD1-OH 2.99Å; D106-Y109 PolarHBondContact OD2-OH 2.91Å; C107-Y109 VanDerWaalsContact C-CD2 3.44Å; C107-Y109 PolarHBondContact O-N 3.18Å; Y109-A163 WeakPolarHBondContact O-CB 3.34Å; Y109-A163 PolarHBondContact O-N 2.93Å; Y109-A163 VanDerWaalsContact O-N 3.1Å
110L98.9Very high92.9Very high0 Ų037.9 Ų37.90%022%0.222CC..EExtended strand (participates in β ladder)trans-122.4165.217060.579.7000110.7G54 I55 Y57 V112 V160 T161 V162 A191 W194 I195G54-L110 PolarHBondContact N-O 3.45Å; I55-L110 HydrophobicContact CB-CD1 3.97Å; I55-L110 HydrophobicContact CD1-CD1 3.97Å; I55-L110 PolarHBondContact N-O 3.25Å; I55-L110 PolarHBondContact O-N 3.04Å; Y57-L110 HydrophobicContact CD1-CB 4.08Å; Y57-L110 HydrophobicContact CD1-CD2 3.89Å; Y57-L110 HydrophobicContact CD1-CG 4.01Å; Y57-L110 HydrophobicContact CG-CD2 4.13Å; L110-V112 HydrophobicContact CD1-CG2 3.83Å; L110-V160 HydrophobicContact CB-CG1 4.25Å; L110-V160 HydrophobicContact CD1-CG1 4.18Å; L110-T161 CarbonylContact C-O 3.6Å; L110-T161 VanDerWaalsContact CA-O 3.25Å; L110-T161 WeakPolarHBondContact CA-O 3.43Å; L110-T161 WeakPolarHBondContact CB-O 3.44Å; L110-V162 HydrophobicContact CB-CG2 4.18Å; L110-A191 HydrophobicContact CD2-CB 4.29Å; L110-W194 HydrophobicContact CD1-CE3 4.06Å; L110-W194 HydrophobicContact CD1-CH2 3.9Å; L110-W194 HydrophobicContact CD1-CZ3 3.63Å; L110-W194 HydrophobicContact CD2-CD2 3.95Å; L110-W194 HydrophobicContact CD2-CE3 3.52Å; L110-W194 HydrophobicContact CD2-CG 4.44Å; L110-W194 HydrophobicContact CD2-CZ3 3.98Å; L110-W194 HydrophobicContact CG-CE3 4.38Å; L110-W194 HydrophobicContact CG-CZ3 4.42Å; L110-I195 HydrophobicContact CD2-CD1 4.39Å; L110-I195 HydrophobicContact CD2-CG1 4.19Å
111N98.9Very high94.7Very high4 Ų441.5 Ų41.52%0.02125%0.248CC..EExtended strand (participates in β ladder)trans-130.5137.5-179.8-41.3-83.1000109.1F52 L53 G54 Y86 F113 V160 T161F52-N111 CarbonylContact O-C 3.58Å; F52-N111 WeakPolarHBondContact O-CA 3.48Å; L53-N111 WeakPolarHBondContact CA-OD1 3.39Å; L53-N111 HydrophobicContact CD2-CB 3.86Å; G54-N111 PolarHBondContact N-OD1 3.2Å; Y86-N111 VanDerWaalsContact CD1-OD1 3.32Å; Y86-N111 WeakPolarHBondContact CD1-OD1 3.27Å; Y86-N111 HydrophobicContact CE1-CB 4.11Å; Y86-N111 VanDerWaalsContact CE1-CG 3.43Å; Y86-N111 WeakPolarHBondContact CE1-ND2 3.32Å; N111-F113 HydrophobicContact CB-CE2 3.83Å; N111-F113 HydrophobicContact CB-CZ 3.92Å; N111-V160 CarbonylContact O-C 3.58Å; N111-V160 VanDerWaalsContact O-CA 3.23Å; N111-V160 WeakPolarHBondContact O-CA 3.44Å; N111-V160 WeakPolarHBondContact O-CG1 3.23Å; N111-T161 WeakPolarHBondContact CB-OG1 3.44Å; N111-T161 PolarHBondContact N-O 3.08Å; N111-T161 PolarHBondContact ND2-O 2.9Å; N111-T161 PolarHBondContact ND2-OG1 3.1Å; N111-T161 PolarHBondContact O-N 3.19Å
112V98.9Very high96Very high0 Ų043.1 Ų43.10%024%0.238CC..EExtended strand (participates in β ladder)trans-118.3128.5-177.2-179.80000109.8F52 I55 L110 I158 V160 I199 F202F52-V112 PolarHBondContact N-O 3.14Å; F52-V112 PolarHBondContact O-N 2.95Å; I55-V112 HydrophobicContact CD1-CB 4.31Å; I55-V112 HydrophobicContact CD1-CG2 3.8Å; L110-V112 HydrophobicContact CD1-CG2 3.83Å; V112-I158 HydrophobicContact CG1-CG2 3.84Å; V112-V160 HydrophobicContact CG2-CG1 4.38Å; V112-V160 HydrophobicContact CG2-CG2 4.22Å; V112-I199 HydrophobicContact CG1-CD1 4.22Å; V112-I199 HydrophobicContact CG2-CD1 4.38Å; V112-F202 HydrophobicContact CB-CD1 4.17Å; V112-F202 HydrophobicContact CB-CE1 4.17Å; V112-F202 HydrophobicContact CG1-CB 4.16Å; V112-F202 HydrophobicContact CG1-CD1 3.68Å; V112-F202 HydrophobicContact CG1-CE1 4.18Å; V112-F202 HydrophobicContact CG1-CG 3.91Å; V112-F202 HydrophobicContact CG2-CE1 4.32Å; V112-F202 HydrophobicContact CG2-CZ 4.36Å
113F98.7Very high96.5Very high0 Ų038.5 Ų38.50%023%0.227CC..EExtended strand (participates in β ladder)trans-119.4114.6175.8-50.9-89.9000108.1T51 L53 Y86 N111 P145 I148 H149 I158 F159 T161T51-F113 HydrophobicContact CG2-CD1 3.89Å; T51-F113 HydrophobicContact CG2-CE1 3.69Å; L53-F113 HydrophobicContact CD2-CE1 3.71Å; L53-F113 HydrophobicContact CD2-CZ 3.6Å; Y86-F113 HydrophobicContact CE1-CZ 4.45Å; Y86-F113 VanDerWaalsContact OH-CZ 3.29Å; Y86-F113 WeakPolarHBondContact OH-CZ 3.16Å; N111-F113 HydrophobicContact CB-CE2 3.83Å; N111-F113 HydrophobicContact CB-CZ 3.92Å; F113-P145 HydrophobicContact CD1-CB 4.35Å; F113-P145 HydrophobicContact CE1-CB 3.73Å; F113-P145 HydrophobicContact CE1-CG 4.08Å; F113-I148 HydrophobicContact CB-CG2 3.73Å; F113-I148 HydrophobicContact CD1-CB 4.4Å; F113-I148 HydrophobicContact CD1-CG2 4.2Å; F113-I148 HydrophobicContact CD2-CB 4.48Å; F113-I148 HydrophobicContact CD2-CD1 4.02Å; F113-I148 HydrophobicContact CD2-CG2 3.71Å; F113-I148 HydrophobicContact CE1-CD1 4.29Å; F113-I148 HydrophobicContact CE2-CD1 3.67Å; F113-I148 HydrophobicContact CE2-CG2 4.44Å; F113-I148 HydrophobicContact CG-CB 4.27Å; F113-I148 HydrophobicContact CG-CG2 3.6Å; F113-I148 HydrophobicContact CZ-CD1 3.84Å; F113-H149 AromaticContact CD1-NE2 3.82Å; F113-I158 WeakPolarHBondContact O-CA 3.46Å; F113-F159 HydrophobicContact CB-CB 4.42Å; F113-F159 HydrophobicContact CD2-CB 4.49Å; F113-F159 VanDerWaalsContact CD2-O 3.32Å; F113-F159 WeakPolarHBondContact CD2-O 3.25Å; F113-F159 PolarHBondContact N-O 3.22Å; F113-F159 PolarHBondContact O-N 2.96Å; F113-T161 HydrophobicContact CE2-CG2 4.29Å
114A98.3Very high96.8Very high0 Ų035.9 Ų35.90%021%0.214CC..EExtended strand (participates in β ladder)trans-128.6131.5-175.800000110.9G49 R50 I158G49-A114 CarbonylContact C-O 3.56Å; G49-A114 WeakPolarHBondContact CA-O 3.03Å; R50-A114 PolarHBondContact N-O 3.19Å; R50-A114 PolarHBondContact O-N 3.35Å; A114-I158 HydrophobicContact CB-CD1 3.88Å; A114-I158 HydrophobicContact CB-CG1 3.92Å
115G96.3Very high97Very high1 Ų134.5 Ų34.51%0.0120%0.204CC..EExtended strand (participates in β ladder)trans-71.7164.7176.800000112.5N117 C118 A153G115-N117 VanDerWaalsContact C-N 3.27Å; G115-N117 PolarHBondContact O-N 2.83Å; G115-C118 PolarHBondContact O-N 3.42Å; G115-A153 VanDerWaalsContact CA-O 3.26Å; G115-A153 WeakPolarHBondContact CA-O 3.26Å
116N94.4Very high97.1Very high79 Ų7933.4 Ų33.442%0.42220%0.199SC..THydrogen-bonded Turntrans-61-33.8179.2-71.8-24.6000113.9V47 V48 G49 C118V47-N116 PolarHBondContact O-ND2 3.06Å; V48-N116 VanDerWaalsContact C-CG 3.49Å; V48-N116 PolarHBondContact O-N 2.88Å; V48-N116 VanDerWaalsContact O-N 3.14Å; G49-N116 VanDerWaalsContact CA-OD1 3.29Å; G49-N116 WeakPolarHBondContact CA-OD1 3.1Å; G49-N116 PolarHBondContact N-OD1 2.9Å; N116-C118 VanDerWaalsContact C-N 3.27Å; N116-C118 PolarHBondContact O-N 3.43Å
117N95.7Very high97.1Very high94 Ų9431.2 Ų31.250%0.50319%0.187SC..THydrogen-bonded Turntrans-76.1-16.9-177.5-60-20.2000112.6G115 T119 D156G115-N117 VanDerWaalsContact C-N 3.27Å; G115-N117 PolarHBondContact O-N 2.83Å; N117-T119 PolarHBondContact O-N 2.86Å; N117-D156 WeakPolarHBondContact CB-OD1 3.3Å; N117-D156 PolarHBondContact ND2-OD1 3.41Å
118C96.5Very high97.2Very high1 Ų131.2 Ų31.21%0.00719%0.187CC..  trans-75.5100.2179.1-580000110.1G115 N116 C124 I158G115-C118 PolarHBondContact O-N 3.42Å; N116-C118 VanDerWaalsContact C-N 3.27Å; N116-C118 PolarHBondContact O-N 3.43Å; C118-C124 WeakPolarHBondContact CA-SG 3.49Å; C118-C124 HydrophobicContact CB-CB 3.78Å; C118-C124 WeakPolarHBondContact CB-SG 3.4Å; C118-C124 WeakPolarHBondContact SG-CB 3.49Å; C118-C124 CovalentContact SG-SG 2.04Å; C118-C124 PolarHBondContact SG-SG 3.3Å; C118-I158 HydrophobicContact CB-CD1 4.19Å; C118-I158 HydrophobicContact CB-CG1 4.16Å
119T94.6Very high97.2Very high49 Ų4931.1 Ų31.130%0.30119%0.187SC..  trans-126.3169.3-174.163.70000111.2N117 S121 E122 P123N117-T119 PolarHBondContact O-N 2.86Å; T119-S121 PolarHBondContact O-N 2.68Å; T119-S121 PolarHBondContact OG1-OG 3.47Å; T119-S121 VanDerWaalsContact OG1-OG 3.1Å; T119-E122 PolarHBondContact N-O 3.37Å; T119-E122 CarbonylContact O-C 3.59Å; T119-E122 PolarHBondContact O-N 3.03Å; T119-E122 PolarHBondContact OG1-N 3.03Å; T119-E122 VanDerWaalsContact OG1-N 3.13Å; T119-P123 WeakPolarHBondContact O-CA 3.43Å
120A91.3Very high97.2Very high95 Ų9529.8 Ų29.879%0.78518%0.182SC*.SBendtrans-65.1-28.7176.100000112.8
121S94Very high97Very high103 Ų10330 Ų3072%0.7218%0.183SC*.SBendtrans-81.2-29.7176.2440000113.1T119T119-S121 PolarHBondContact O-N 2.68Å; T119-S121 PolarHBondContact OG1-OG 3.47Å; T119-S121 VanDerWaalsContact OG1-OG 3.1Å
122E94.8Very high96.8Very high135 Ų13530 Ų3063%0.63118%0.184SC*.SBendtrans-128.675.8-179.4-63.2-178.2166.200108.9T119T119-E122 PolarHBondContact N-O 3.37Å; T119-E122 CarbonylContact O-C 3.59Å; T119-E122 PolarHBondContact O-N 3.03Å; T119-E122 PolarHBondContact OG1-N 3.03Å; T119-E122 VanDerWaalsContact OG1-N 3.13Å
123P97.8Very high96.4Very high50 Ų5030.2 Ų30.233%0.32519%0.186SC..PPolyproline II helixtrans-74.8131.5-173.330.6-36000111.9T119 G203 D205 R208T119-P123 WeakPolarHBondContact O-CA 3.43Å; P123-G203 CarbonylContact C-O 3.55Å; P123-G203 VanDerWaalsContact CA-O 3.3Å; P123-G203 WeakPolarHBondContact CA-O 3.34Å; P123-D205 HydrophobicContact CB-CB 3.96Å; P123-D205 HydrophobicContact CG-CB 4.37Å; P123-R208 PolarHBondContact O-NH2 2.98Å
124C98.8Very high95.9Very high7 Ų733.6 Ų33.65%0.04720%0.202CC..EExtended strand (participates in β ladder)trans-85.5148.9-177.7-71.90000112.8C118 D156 I158 G203 G204 D205C118-C124 WeakPolarHBondContact CA-SG 3.49Å; C118-C124 HydrophobicContact CB-CB 3.78Å; C118-C124 WeakPolarHBondContact CB-SG 3.4Å; C118-C124 WeakPolarHBondContact SG-CB 3.49Å; C118-C124 CovalentContact SG-SG 2.04Å; C118-C124 PolarHBondContact SG-SG 3.3Å; C124-D156 VanDerWaalsContact CB-O 3.29Å; C124-D156 WeakPolarHBondContact CB-O 3.14Å; C124-D156 PolarHBondContact SG-O 3.14Å; C124-I158 HydrophobicContact CB-CG1 4.06Å; C124-G203 PolarHBondContact N-O 3.27Å; C124-G204 CarbonylContact O-C 3.6Å; C124-G204 WeakPolarHBondContact O-CA 3.31Å; C124-D205 WeakPolarHBondContact O-CB 3.48Å; C124-D205 PolarHBondContact O-N 3.07Å
125P98.7Very high95.7Very high5 Ų533.9 Ų33.93%0.03220%0.203CC..EExtended strand (participates in β ladder)trans-60.3153.2168.229.9-37000111.6D156 V157 I158 R208 V521 K522P125-D156 WeakPolarHBondContact CD-O 3.32Å; P125-V157 HydrophobicContact CG-CG2 4.24Å; P125-I158 PolarHBondContact O-N 3.18Å; P125-R208 HydrophobicContact CB-CB 4.17Å; P125-V521 HydrophobicContact CB-CG1 3.96Å; P125-V521 HydrophobicContact CG-CG1 4.13Å; P125-K522 HydrophobicContact CG-CG 4.03Å
126V98.9Very high95.4Very high0 Ų034.2 Ų34.20%021%0.205CC..EExtended strand (participates in β ladder)trans-118.4130.7-172.2-175.60000110.2I158 V160 I195 I199 R208 V209 T210V126-I158 CarbonylContact C-O 3.52Å; V126-I158 WeakPolarHBondContact CA-O 3.33Å; V126-I158 HydrophobicContact CG1-CG2 4.48Å; V126-I158 HydrophobicContact CG2-CB 4.35Å; V126-V160 HydrophobicContact CG1-CG2 3.95Å; V126-I195 HydrophobicContact CG1-CG2 4.13Å; V126-I199 HydrophobicContact CG1-CD1 4.42Å; V126-I199 HydrophobicContact CG1-CG1 4Å; V126-I199 HydrophobicContact CG2-CG1 3.69Å; V126-I199 HydrophobicContact CG2-CG2 4.16Å; V126-R208 PolarHBondContact N-O 3.23Å; V126-V209 HydrophobicContact CB-CG2 4.34Å; V126-V209 WeakPolarHBondContact O-CA 3.24Å; V126-T210 PolarHBondContact O-N 3.32Å
127V98.9Very high95.2Very high0 Ų031.2 Ų31.20%019%0.188CC..EExtended strand (participates in β ladder)trans-105.6127.7168.8176.90000109.4V157 I158 F159 V160 T210 M212 V521V127-V157 HydrophobicContact CB-CG1 4.4Å; V127-V157 HydrophobicContact CG2-CG1 3.66Å; V127-I158 PolarHBondContact N-O 3.05Å; V127-F159 HydrophobicContact CB-CD2 3.76Å; V127-F159 HydrophobicContact CB-CE2 3.99Å; V127-F159 HydrophobicContact CG1-CD2 3.83Å; V127-F159 HydrophobicContact CG1-CE2 3.51Å; V127-F159 HydrophobicContact CG1-CZ 4.18Å; V127-F159 HydrophobicContact CG2-CD2 4.44Å; V127-V160 PolarHBondContact O-N 2.9Å; V127-T210 CarbonylContact C-O 3.53Å; V127-T210 WeakPolarHBondContact CA-O 3.38Å; V127-M212 HydrophobicContact CG1-CB 3.7Å; V127-M212 HydrophobicContact CG1-CG 4.46Å; V127-M212 HydrophobicContact CG1-SD 3.93Å; V127-V521 HydrophobicContact CG2-CB 4.27Å; V127-V521 HydrophobicContact CG2-CG1 3.66Å; V127-V521 HydrophobicContact CG2-CG2 3.53Å
128I98.9Very high95.1Very high1 Ų127.9 Ų27.91%0.00517%0.17CC..EExtended strand (participates in β ladder)trans-103.6110.5170.5-47.8179.1000107.4I130 V162 M192 I195 V209 T210 L211 M212I128-I130 HydrophobicContact CG2-CD1 4.1Å; I128-V162 HydrophobicContact CG2-CG2 3.76Å; I128-M192 HydrophobicContact CD1-CB 4.48Å; I128-M192 HydrophobicContact CD1-CG 3.97Å; I128-I195 HydrophobicContact CB-CD1 4.37Å; I128-I195 HydrophobicContact CD1-CB 4.3Å; I128-I195 HydrophobicContact CD1-CD1 3.53Å; I128-I195 HydrophobicContact CD1-CG2 4.05Å; I128-I195 HydrophobicContact CG1-CD1 3.7Å; I128-I195 HydrophobicContact CG1-CG2 4.4Å; I128-I195 HydrophobicContact CG2-CD1 3.85Å; I128-V209 HydrophobicContact CD1-CG1 3.4Å; I128-V209 VanDerWaalsContact CD1-CG1 3.4Å; I128-V209 HydrophobicContact CG1-CG1 3.82Å; I128-T210 PolarHBondContact N-O 3.05Å; I128-L211 HydrophobicContact CB-CD1 3.78Å; I128-L211 HydrophobicContact CG2-CD1 3.89Å; I128-M212 PolarHBondContact O-N 3.48Å; I128-M212 VanDerWaalsContact O-O 3.09Å
129F98.9Very high94.9Very high1 Ų128.1 Ų28.10%0.00417%0.172CC..EExtended strand (participates in β ladder)trans-97.3121.7-178-172.8-93.9000112.3H131 F143 F159 V160 T161 V162 M212 H214 L491 L495F129-H131 HydrophobicContact CE1-CB 4.18Å; F129-F143 AromaticContact CD1-CE2 3.94Å; F129-F143 HydrophobicContact CD1-CE2 3.94Å; F129-F143 HydrophobicContact CD1-CZ 4.07Å; F129-F143 HydrophobicContact CE1-CE1 4.27Å; F129-F143 AromaticContact CE1-CE2 3.7Å; F129-F143 HydrophobicContact CE1-CE2 3.7Å; F129-F143 AromaticContact CE1-CZ 3.38Å; F129-F143 HydrophobicContact CE1-CZ 3.38Å; F129-F143 HydrophobicContact CZ-CZ 4.15Å; F129-F159 HydrophobicContact CB-CD1 4.44Å; F129-F159 HydrophobicContact CB-CE1 3.44Å; F129-F159 VanDerWaalsContact CB-CE1 3.44Å; F129-F159 HydrophobicContact CB-CE2 4.47Å; F129-F159 HydrophobicContact CB-CZ 3.47Å; F129-F159 VanDerWaalsContact CB-CZ 3.47Å; F129-F159 AromaticContact CD2-CZ 3.88Å; F129-F159 HydrophobicContact CD2-CZ 3.88Å; F129-F159 AromaticContact CG-CE1 3.95Å; F129-F159 HydrophobicContact CG-CE1 3.95Å; F129-F159 AromaticContact CG-CZ 3.77Å; F129-F159 HydrophobicContact CG-CZ 3.77Å; F129-V160 PolarHBondContact N-O 3.47Å; F129-T161 HydrophobicContact CB-CG2 4.4Å; F129-V162 PolarHBondContact O-N 3.07Å; F129-M212 CarbonylContact C-O 3.57Å; F129-M212 VanDerWaalsContact CA-O 3.31Å; F129-M212 WeakPolarHBondContact CA-O 3.47Å; F129-M212 HydrophobicContact CD2-CB 4.22Å; F129-M212 HydrophobicContact CD2-CE 4.44Å; F129-M212 HydrophobicContact CD2-CG 3.76Å; F129-M212 HydrophobicContact CD2-SD 4Å; F129-M212 HydrophobicContact CE2-CE 4.35Å; F129-M212 HydrophobicContact CE2-CG 4.15Å; F129-M212 HydrophobicContact CE2-SD 4.47Å; F129-H214 HydrophobicContact CZ-CB 4.27Å; F129-L491 HydrophobicContact CE2-CD2 4.22Å; F129-L491 HydrophobicContact CZ-CD1 4.32Å; F129-L491 HydrophobicContact CZ-CD2 4.13Å; F129-L495 HydrophobicContact CD1-CD1 4.17Å; F129-L495 HydrophobicContact CD2-CD1 4.02Å; F129-L495 HydrophobicContact CE1-CD1 3.75Å; F129-L495 HydrophobicContact CE2-CD1 3.58Å; F129-L495 HydrophobicContact CG-CD1 4.3Å; F129-L495 HydrophobicContact CZ-CD1 3.43Å; F129-L495 VanDerWaalsContact CZ-CD1 3.43Å
130I98.7Very high94.9Very high0 Ų026 Ų260%016%0.159CC..EExtended strand (participates in β ladder)trans-104.2114176.3-49-52.7000109I128 V162 Y164 I188 L211 M212 G213 H214 A220 V221I128-I130 HydrophobicContact CG2-CD1 4.1Å; I130-V162 HydrophobicContact CD1-CB 4.13Å; I130-V162 HydrophobicContact CD1-CG2 4.47Å; I130-Y164 HydrophobicContact CG2-CD1 4.28Å; I130-Y164 HydrophobicContact CG2-CE1 3.69Å; I130-I188 HydrophobicContact CD1-CD1 4.43Å; I130-I188 HydrophobicContact CD1-CG1 4.19Å; I130-I188 HydrophobicContact CD1-CG2 3.65Å; I130-I188 HydrophobicContact CG1-CG2 4.23Å; I130-I188 HydrophobicContact CG2-CD1 3.71Å; I130-I188 HydrophobicContact CG2-CG1 4.48Å; I130-L211 HydrophobicContact CD1-CD1 4.11Å; I130-L211 HydrophobicContact CG1-CD1 3.81Å; I130-M212 PolarHBondContact N-O 3.08Å; I130-G213 WeakPolarHBondContact O-CA 3.47Å; I130-H214 PolarHBondContact O-N 2.56Å; I130-A220 HydrophobicContact CG2-CB 4.37Å; I130-V221 HydrophobicContact CB-CG2 4.3Å; I130-V221 HydrophobicContact CG1-CG2 4.06Å
131H95.9Very high94.9Very high5 Ų523.5 Ų23.52%0.02314%0.136CC..  trans-69.8160.5-178.168.182.8000112.7F129 D138 F143 Y164 G217F129-H131 HydrophobicContact CE1-CB 4.18Å; H131-D138 PolarHBondContact CE1-O 3.37Å; H131-F143 HydrophobicContact CB-CE2 4.35Å; H131-Y164 AromaticContact CD2-CE1 3.77Å; H131-Y164 AromaticContact CE1-CE1 3.7Å; H131-Y164 AromaticContact NE2-CD1 3.87Å; H131-Y164 AromaticContact NE2-CE1 3.5Å; H131-Y164 PolarHBondContact O-OH 3.12Å; H131-Y164 VanDerWaalsContact O-OH 3.06Å; H131-G217 VanDerWaalsContact O-CA 3.23Å; H131-G217 WeakPolarHBondContact O-CA 3.37Å; H131-G217 PolarHBondContact O-N 3.35Å
132G93.5Very high94.8Very high5 Ų521 Ų215%0.05211%0.113CC..  trans-82.5-153.9174.800000112.9H214 S216G132-H214 WeakPolarHBondContact CA-O 3.09Å; G132-H214 PolarHBondContact N-O 3.3Å; G132-S216 VanDerWaalsContact C-OG 3.24Å; G132-S216 WeakPolarHBondContact CA-OG 3.39Å
133G90.3Very high94.6Very high4 Ų414.8 Ų14.84%0.0418%0.084CC..SBendtrans109.934174.900000114.9F135 D136 F137 D138 S216G133-F135 PolarHBondContact O-N 3.3Å; G133-D136 PolarHBondContact O-N 3.43Å; G133-F137 VanDerWaalsContact CA-CE2 3.48Å; G133-F137 WeakPolarHBondContact CA-O 3.43Å; G133-F137 VanDerWaalsContact O-CD1 3.26Å; G133-F137 WeakPolarHBondContact O-CD1 3.37Å; G133-F137 WeakPolarHBondContact O-CE1 3.25Å; G133-F137 WeakPolarHBondContact O-CG 3.4Å; G133-F137 PolarHBondContact O-N 2.62Å; G133-D138 WeakPolarHBondContact CA-OD2 3.2Å; G133-S216 PolarHBondContact N-OG 2.93Å; G133-S216 VanDerWaalsContact N-OG 3.14Å
134E89.7Confident94.4Very high70 Ų7016 Ų1633%0.3279%0.088SC..THydrogen-bonded Turntrans5820.5176.1-58177-158.800114.1R96 D136 F137 S216R96-E134 IonicContact NH1-OE1 3.53Å; E134-D136 PolarHBondContact O-N 2.98Å; E134-F137 HydrophobicContact CB-CE1 3.86Å; E134-F137 HydrophobicContact CB-CZ 4.29Å; E134-F137 HydrophobicContact CG-CE1 3.87Å; E134-F137 HydrophobicContact CG-CZ 3.9Å; E134-S216 PolarHBondContact N-OG 3.08Å
135F93.1Very high94.3Very high6 Ų617 Ų173%0.0269%0.094CC..THydrogen-bonded Turntrans62.49-167-58.5-76.7000115.1G133 Y164 L166 G167 F171 S216 A220 P340G133-F135 PolarHBondContact O-N 3.3Å; F135-Y164 HydrophobicContact CD1-CE2 4.42Å; F135-L166 CarbonylContact O-C 3.52Å; F135-L166 VanDerWaalsContact O-CA 3.3Å; F135-L166 WeakPolarHBondContact O-CA 3.28Å; F135-L166 WeakPolarHBondContact O-CB 3.06Å; F135-L166 WeakPolarHBondContact O-CD2 3.45Å; F135-G167 PolarHBondContact O-N 2.66Å; F135-F171 HydrophobicContact CB-CD2 4.25Å; F135-F171 HydrophobicContact CB-CE2 3.68Å; F135-F171 HydrophobicContact CB-CZ 4.19Å; F135-F171 AromaticContact CD1-CE2 3.97Å; F135-F171 HydrophobicContact CD1-CE2 3.97Å; F135-F171 AromaticContact CD1-CZ 3.63Å; F135-F171 HydrophobicContact CD1-CZ 3.63Å; F135-F171 HydrophobicContact CE1-CZ 4.31Å; F135-F171 HydrophobicContact CG-CE2 4.15Å; F135-F171 HydrophobicContact CG-CZ 4.16Å; F135-S216 WeakPolarHBondContact CE1-O 3.31Å; F135-S216 WeakPolarHBondContact CZ-O 3.12Å; F135-S216 PolarHBondContact N-OG 3.32Å; F135-A220 HydrophobicContact CE1-CB 3.92Å; F135-A220 HydrophobicContact CZ-CB 4.3Å; F135-P340 HydrophobicContact CE1-CG 3.97Å; F135-P340 HydrophobicContact CE2-CG 4.31Å; F135-P340 HydrophobicContact CZ-CG 3.83Å
136D90.9Very high94.1Very high8 Ų820.2 Ų20.24%0.04311%0.111CC..THydrogen-bonded Turntrans-116.7-25.9-173.2-84.7-31.5000114.3Q92 G133 E134 G167 Y296 Q300 T338Q92-D136 WeakPolarHBondContact CB-O 3.32Å; G133-D136 PolarHBondContact O-N 3.43Å; E134-D136 PolarHBondContact O-N 2.98Å; D136-G167 WeakPolarHBondContact OD1-CA 3.38Å; D136-Y296 PolarHBondContact OD1-OH 3.29Å; D136-Y296 PolarHBondContact OD2-OH 2.84Å; D136-Q300 PolarHBondContact OD2-NE2 3.22Å; D136-T338 PolarHBondContact OD1-OG1 2.61Å; D136-T338 PolarHBondContact OD2-OG1 2.84Å
137F90.5Very high93.9Very high16 Ų1621.2 Ų21.27%0.0712%0.117CC..SBendtrans-149.1-171.9-173.257.8-94.4000112.7R94 G133 E134R94-F137 HydrophobicContact CB-CB 4.36Å; R94-F137 HydrophobicContact CB-CD1 4.22Å; R94-F137 HydrophobicContact CB-CG 4.5Å; R94-F137 WeakPolarHBondContact O-CB 3.3Å; G133-F137 VanDerWaalsContact CA-CE2 3.48Å; G133-F137 WeakPolarHBondContact CA-O 3.43Å; G133-F137 VanDerWaalsContact O-CD1 3.26Å; G133-F137 WeakPolarHBondContact O-CD1 3.37Å; G133-F137 WeakPolarHBondContact O-CE1 3.25Å; G133-F137 WeakPolarHBondContact O-CG 3.4Å; G133-F137 PolarHBondContact O-N 2.62Å; E134-F137 HydrophobicContact CB-CE1 3.86Å; E134-F137 HydrophobicContact CB-CZ 4.29Å; E134-F137 HydrophobicContact CG-CE1 3.87Å; E134-F137 HydrophobicContact CG-CZ 3.9Å
138D91.7Very high93.9Very high24 Ų2421.3 Ų21.313%0.12812%0.118CC..  trans71.6174.6-171.7-64.2-27.8000113.4Q92 H131 G133 M142Q92-D138 PolarHBondContact NE2-O 3.41Å; H131-D138 PolarHBondContact CE1-O 3.37Å; G133-D138 WeakPolarHBondContact CA-OD2 3.2Å; D138-M142 HydrophobicContact CB-SD 4.03Å
139S93.9Very high93.8Very high7 Ų721.2 Ų21.25%0.04912%0.117CC..  trans-169.3152.6-172.3173.30000111.6A89 S141 M142A89-S139 VanDerWaalsContact CB-CB 3.46Å; A89-S139 WeakPolarHBondContact CB-OG 3.38Å; S139-S141 WeakPolarHBondContact CB-OG 3.42Å; S139-S141 PolarHBondContact O-N 3.41Å; S139-S141 VanDerWaalsContact O-N 3.08Å; S139-S141 PolarHBondContact OG-N 2.99Å; S139-S141 PolarHBondContact OG-OG 3.44Å; S139-M142 WeakPolarHBondContact O-CG 3.41Å; S139-M142 PolarHBondContact O-N 2.81Å; S139-M142 VanDerWaalsContact O-SD 3.38Å
140P94.4Very high93.7Very high4 Ų425.4 Ų25.43%0.02614%0.137CC..G310 helixtrans-53.7-26168.3-29.839.5000115.3Y86 M142 F143 V162 A163Y86-P140 HydrophobicContact CE1-CB 4.4Å; P140-M142 PolarHBondContact O-N 3.13Å; P140-M142 VanDerWaalsContact O-N 3.1Å; P140-F143 VanDerWaalsContact O-CD2 3.32Å; P140-F143 WeakPolarHBondContact O-CD2 3.34Å; P140-F143 PolarHBondContact O-N 3.18Å; P140-F143 VanDerWaalsContact O-N 3.16Å; P140-V162 VanDerWaalsContact CG-C 3.43Å; P140-V162 WeakPolarHBondContact CG-O 3.46Å; P140-A163 HydrophobicContact CG-CB 3.96Å
141S91.4Very high93.6Very high43 Ų4325.9 Ų25.930%0.30114%0.139SC..G310 helixtrans-66.7-7.8-179.361.10000114.4S139 F143S139-S141 WeakPolarHBondContact CB-OG 3.42Å; S139-S141 PolarHBondContact O-N 3.41Å; S139-S141 VanDerWaalsContact O-N 3.08Å; S139-S141 PolarHBondContact OG-N 2.99Å; S139-S141 PolarHBondContact OG-OG 3.44Å; S141-F143 VanDerWaalsContact C-N 3.33Å
142M90.2Very high93.7Very high49 Ų4925.7 Ų25.724%0.24114%0.139CC..G310 helixtrans-79.5-15.3174.274.7-165-105.100113.7D138 S139 P140 L497D138-M142 HydrophobicContact CB-SD 4.03Å; S139-M142 WeakPolarHBondContact O-CG 3.41Å; S139-M142 PolarHBondContact O-N 2.81Å; S139-M142 VanDerWaalsContact O-SD 3.38Å; P140-M142 PolarHBondContact O-N 3.13Å; P140-M142 VanDerWaalsContact O-N 3.1Å; M142-L497 HydrophobicContact CE-CD1 3.3Å; M142-L497 HydrophobicContact CE-CD2 3.48Å; M142-L497 VanDerWaalsContact CE-CD2 3.48Å; M142-L497 HydrophobicContact CE-CG 4.02Å; M142-L497 HydrophobicContact CG-CD2 4.09Å
143F92.3Very high93.9Very high5 Ų525.5 Ų25.52%0.02214%0.136CC..SBendtrans-89.5136.7-178.6-57.4-64000110.9Y86 F129 H131 P140 S141 P145 I148 T161 L495 L497Y86-F143 PolarHBondContact OH-O 2.84Å; F129-F143 AromaticContact CD1-CE2 3.94Å; F129-F143 HydrophobicContact CD1-CE2 3.94Å; F129-F143 HydrophobicContact CD1-CZ 4.07Å; F129-F143 HydrophobicContact CE1-CE1 4.27Å; F129-F143 AromaticContact CE1-CE2 3.7Å; F129-F143 HydrophobicContact CE1-CE2 3.7Å; F129-F143 AromaticContact CE1-CZ 3.38Å; F129-F143 HydrophobicContact CE1-CZ 3.38Å; F129-F143 HydrophobicContact CZ-CZ 4.15Å; H131-F143 HydrophobicContact CB-CE2 4.35Å; P140-F143 VanDerWaalsContact O-CD2 3.32Å; P140-F143 WeakPolarHBondContact O-CD2 3.34Å; P140-F143 PolarHBondContact O-N 3.18Å; P140-F143 VanDerWaalsContact O-N 3.16Å; S141-F143 VanDerWaalsContact C-N 3.33Å; F143-P145 WeakPolarHBondContact O-CD 3.46Å; F143-I148 HydrophobicContact CB-CD1 3.81Å; F143-I148 HydrophobicContact CB-CG1 4.49Å; F143-T161 HydrophobicContact CD2-CG2 4.15Å; F143-L495 HydrophobicContact CD1-CB 3.78Å; F143-L495 HydrophobicContact CD1-CD1 4.02Å; F143-L495 HydrophobicContact CD1-CG 4.44Å; F143-L495 HydrophobicContact CE1-CB 3.85Å; F143-L495 HydrophobicContact CE1-CD1 3.52Å; F143-L495 HydrophobicContact CE1-CG 4.31Å; F143-L495 HydrophobicContact CZ-CD1 3.99Å; F143-L497 HydrophobicContact CD1-CD2 3.72Å; F143-L497 HydrophobicContact CD1-CG 4.28Å; F143-L497 HydrophobicContact CE1-CD1 3.93Å; F143-L497 HydrophobicContact CE1-CD2 3.72Å; F143-L497 HydrophobicContact CE1-CG 3.98Å
144D93.1Very high94.3Very high77 Ų7729.7 Ų29.741%0.41216%0.156SC..  trans-78.9120.2173.8-173.4-22.7000109.7N146 V147 I148D144-N146 PolarHBondContact O-N 2.92Å; D144-N146 WeakPolarHBondContact OD1-CB 3.4Å; D144-N146 PolarHBondContact OD1-N 2.9Å; D144-V147 HydrophobicContact CB-CB 4.24Å; D144-V147 HydrophobicContact CB-CG2 3.9Å; D144-V147 PolarHBondContact O-N 2.9Å; D144-I148 PolarHBondContact O-N 3Å; D144-I148 VanDerWaalsContact O-N 3.16Å
145P95.4Very high94.6Very high26 Ų2630.9 Ų30.917%0.16916%0.161CC..Hα-helixtrans-50.3-39174-3239.8000114.1L53 Y86 F113 F143 I148 H149L53-P145 HydrophobicContact CD1-CG 4.44Å; Y86-P145 HydrophobicContact CE2-CG 3.73Å; F113-P145 HydrophobicContact CD1-CB 4.35Å; F113-P145 HydrophobicContact CE1-CB 3.73Å; F113-P145 HydrophobicContact CE1-CG 4.08Å; F143-P145 WeakPolarHBondContact O-CD 3.46Å; P145-I148 PolarHBondContact O-N 3.08Å; P145-H149 PolarHBondContact O-CD2 3.45Å; P145-H149 PolarHBondContact O-N 2.92Å
146N94.9Very high94.8Very high73 Ų7333.2 Ų33.239%0.3917%0.174SC..Hα-helixtrans-67.1-41.6-177.5-68.4-30.4000111.1I43 D144 I148 H149 E150I43-N146 HydrophobicContact CD1-CB 4.3Å; D144-N146 PolarHBondContact O-N 2.92Å; D144-N146 WeakPolarHBondContact OD1-CB 3.4Å; D144-N146 PolarHBondContact OD1-N 2.9Å; N146-I148 VanDerWaalsContact C-N 3.31Å; N146-I148 PolarHBondContact O-N 2.76Å; N146-H149 PolarHBondContact O-N 3.11Å; N146-H149 VanDerWaalsContact O-N 3.16Å; N146-E150 WeakPolarHBondContact O-CG 3.47Å; N146-E150 PolarHBondContact O-N 3.42Å
147V95.4Very high95.2Very high22 Ų2232.8 Ų32.813%0.13317%0.172CC..Hα-helixtrans-63.9-40176.2178.20000110.9D144 H149 E150 N151D144-V147 HydrophobicContact CB-CB 4.24Å; D144-V147 HydrophobicContact CB-CG2 3.9Å; D144-V147 PolarHBondContact O-N 2.9Å; V147-H149 VanDerWaalsContact C-N 3.31Å; V147-H149 PolarHBondContact O-N 2.6Å; V147-E150 PolarHBondContact O-N 2.84Å; V147-N151 VanDerWaalsContact CG1-ND2 3.34Å; V147-N151 WeakPolarHBondContact CG1-ND2 3.47Å; V147-N151 WeakPolarHBondContact O-CB 3.34Å; V147-N151 VanDerWaalsContact O-CG 3.25Å; V147-N151 PolarHBondContact O-N 2.77Å
148I98.1Very high95.6Very high1 Ų132 Ų321%0.00517%0.169CC..Hα-helixtrans-63.2-40.8175.1-63.4171.9000110.8F113 F143 D144 P145 N146 F152 A153 F159 T161F113-I148 HydrophobicContact CB-CG2 3.73Å; F113-I148 HydrophobicContact CD1-CB 4.4Å; F113-I148 HydrophobicContact CD1-CG2 4.2Å; F113-I148 HydrophobicContact CD2-CB 4.48Å; F113-I148 HydrophobicContact CD2-CD1 4.02Å; F113-I148 HydrophobicContact CD2-CG2 3.71Å; F113-I148 HydrophobicContact CE1-CD1 4.29Å; F113-I148 HydrophobicContact CE2-CD1 3.67Å; F113-I148 HydrophobicContact CE2-CG2 4.44Å; F113-I148 HydrophobicContact CG-CB 4.27Å; F113-I148 HydrophobicContact CG-CG2 3.6Å; F113-I148 HydrophobicContact CZ-CD1 3.84Å; F143-I148 HydrophobicContact CB-CD1 3.81Å; F143-I148 HydrophobicContact CB-CG1 4.49Å; D144-I148 PolarHBondContact O-N 3Å; D144-I148 VanDerWaalsContact O-N 3.16Å; P145-I148 PolarHBondContact O-N 3.08Å; N146-I148 VanDerWaalsContact C-N 3.31Å; N146-I148 PolarHBondContact O-N 2.76Å; I148-F152 PolarHBondContact O-N 3.11Å; I148-A153 PolarHBondContact O-N 3.16Å; I148-F159 HydrophobicContact CD1-CD1 4.4Å; I148-F159 HydrophobicContact CG2-CB 3.6Å; I148-F159 HydrophobicContact CG2-CD1 3.78Å; I148-F159 HydrophobicContact CG2-CG 3.83Å; I148-T161 HydrophobicContact CD1-CG2 4.26Å
149H97.9Very high95.9Very high0 Ų030.9 Ų30.90%016%0.163CC..Hα-helixtrans-63-49.4176.3-86.1-71.7000112.3A41 I43 V48 R50 T51 F113 P145 N146 V147 N151 A153 M154A41-H149 VanDerWaalsContact CB-CD2 3.42Å; A41-H149 WeakPolarHBondContact CB-CD2 3.41Å; A41-H149 VanDerWaalsContact CB-NE2 3.26Å; A41-H149 WeakPolarHBondContact CB-NE2 3.36Å; I43-H149 HydrophobicContact CD1-CB 3.93Å; V48-H149 HydrophobicContact CG2-CB 4.11Å; R50-H149 PolarHBondContact O-CE1 2.79Å; T51-H149 PolarHBondContact OG1-NE2 3.33Å; F113-H149 AromaticContact CD1-NE2 3.82Å; P145-H149 PolarHBondContact O-CD2 3.45Å; P145-H149 PolarHBondContact O-N 2.92Å; N146-H149 PolarHBondContact O-N 3.11Å; N146-H149 VanDerWaalsContact O-N 3.16Å; V147-H149 VanDerWaalsContact C-N 3.31Å; V147-H149 PolarHBondContact O-N 2.6Å; H149-N151 VanDerWaalsContact C-N 3.34Å; H149-N151 PolarHBondContact O-N 3.38Å; H149-A153 HydrophobicContact CB-CB 4.32Å; H149-A153 VanDerWaalsContact ND1-CB 3.29Å; H149-A153 WeakPolarHBondContact ND1-CB 3.34Å; H149-A153 PolarHBondContact O-N 2.99Å; H149-M154 WeakPolarHBondContact O-CB 3.45Å; H149-M154 WeakPolarHBondContact O-CG 3.32Å; H149-M154 PolarHBondContact O-N 2.94Å
150E96.2Very high96.2Very high89 Ų8930.6 Ų30.642%0.41616%0.16SC..Hα-helixtrans-61.2-41.6178.8-70.2176169.700112.2I43 N146 V147 M154I43-E150 HydrophobicContact CD1-CG 3.54Å; I43-E150 HydrophobicContact CG2-CG 4.47Å; I43-E150 WeakPolarHBondContact CG2-OE1 3.22Å; N146-E150 WeakPolarHBondContact O-CG 3.47Å; N146-E150 PolarHBondContact O-N 3.42Å; V147-E150 PolarHBondContact O-N 2.84Å; E150-M154 HydrophobicContact CG-SD 4.39Å
151N97.3Very high96.4Very high10 Ų1030.4 Ų30.45%0.05316%0.159CC..Hα-helixtrans-89.2-24.3-170.8-69.7-3.2000114.4V147 H149 A494 L514 I518V147-N151 VanDerWaalsContact CG1-ND2 3.34Å; V147-N151 WeakPolarHBondContact CG1-ND2 3.47Å; V147-N151 WeakPolarHBondContact O-CB 3.34Å; V147-N151 VanDerWaalsContact O-CG 3.25Å; V147-N151 PolarHBondContact O-N 2.77Å; H149-N151 VanDerWaalsContact C-N 3.34Å; H149-N151 PolarHBondContact O-N 3.38Å; N151-A494 PolarHBondContact ND2-O 3.41Å; N151-L514 HydrophobicContact CB-CD1 3.89Å; N151-L514 HydrophobicContact CB-CD2 3.71Å; N151-L514 HydrophobicContact CB-CG 4.47Å; N151-L514 VanDerWaalsContact CG-CD1 3.44Å; N151-L514 WeakPolarHBondContact OD1-CD1 3.48Å; N151-I518 WeakPolarHBondContact O-CD1 3.18Å
152F98.6Very high96.7Very high1 Ų128.4 Ų28.40%0.00415%0.145CC..THydrogen-bonded Turntrans-131.9-52.4-174.7-64.7-85.9000112.7I148 M154 E155 V157 F159 L495 L514I148-F152 PolarHBondContact O-N 3.11Å; F152-M154 PolarHBondContact O-N 3.45Å; F152-E155 CarbonylContact O-C 3.1Å; F152-E155 WeakPolarHBondContact O-CA 3.33Å; F152-E155 WeakPolarHBondContact O-CB 3.46Å; F152-E155 PolarHBondContact O-N 3Å; F152-V157 CarbonylContact C-O 3.46Å; F152-V157 HydrophobicContact CB-CB 4.35Å; F152-V157 HydrophobicContact CD1-CG1 4.41Å; F152-V157 WeakPolarHBondContact O-CB 3.37Å; F152-V157 PolarHBondContact O-N 3.16Å; F152-V157 VanDerWaalsContact O-N 3.1Å; F152-F159 HydrophobicContact CB-CB 4.13Å; F152-F159 HydrophobicContact CB-CD2 3.94Å; F152-F159 HydrophobicContact CB-CG 4.35Å; F152-F159 AromaticContact CD1-CD2 3.63Å; F152-F159 HydrophobicContact CD1-CD2 3.63Å; F152-F159 AromaticContact CD1-CE2 3.86Å; F152-F159 HydrophobicContact CD1-CE2 3.86Å; F152-F159 AromaticContact CD2-CD2 3.76Å; F152-F159 HydrophobicContact CD2-CD2 3.76Å; F152-F159 AromaticContact CD2-CE2 3.9Å; F152-F159 HydrophobicContact CD2-CE2 3.9Å; F152-F159 HydrophobicContact CD2-CG 4.37Å; F152-F159 HydrophobicContact CE1-CD2 4.04Å; F152-F159 AromaticContact CE1-CE2 3.75Å; F152-F159 HydrophobicContact CE1-CE2 3.75Å; F152-F159 HydrophobicContact CE2-CD2 4.17Å; F152-F159 AromaticContact CE2-CE2 3.81Å; F152-F159 HydrophobicContact CE2-CE2 3.81Å; F152-F159 HydrophobicContact CE2-CZ 4.35Å; F152-F159 AromaticContact CG-CD2 3.48Å; F152-F159 HydrophobicContact CG-CD2 3.48Å; F152-F159 VanDerWaalsContact CG-CD2 3.48Å; F152-F159 AromaticContact CG-CE2 3.93Å; F152-F159 HydrophobicContact CG-CE2 3.93Å; F152-F159 HydrophobicContact CG-CG 4.25Å; F152-F159 HydrophobicContact CZ-CD2 4.29Å; F152-F159 AromaticContact CZ-CE2 3.73Å; F152-F159 HydrophobicContact CZ-CE2 3.73Å; F152-F159 HydrophobicContact CZ-CZ 4.47Å; F152-L495 HydrophobicContact CD2-CD2 4.41Å; F152-L495 HydrophobicContact CE2-CD2 3.63Å; F152-L495 HydrophobicContact CZ-CD2 4.33Å; F152-L514 HydrophobicContact CE2-CD2 4.31Å; F152-L514 HydrophobicContact CZ-CD2 4.2Å
153A97.6Very high97.1Very high0 Ų026.4 Ų26.40%014%0.136CC..G310 helixtrans-65.2-41.7-172.500000112.6G115 I148 H149 E155 D156 V157G115-A153 VanDerWaalsContact CA-O 3.26Å; G115-A153 WeakPolarHBondContact CA-O 3.26Å; I148-A153 PolarHBondContact O-N 3.16Å; H149-A153 HydrophobicContact CB-CB 4.32Å; H149-A153 VanDerWaalsContact ND1-CB 3.29Å; H149-A153 WeakPolarHBondContact ND1-CB 3.34Å; H149-A153 PolarHBondContact O-N 2.99Å; A153-E155 PolarHBondContact O-N 2.93Å; A153-D156 PolarHBondContact O-N 2.89Å; A153-V157 WeakPolarHBondContact CA-O 3.08Å
154M96.9Very high97.4Very high93 Ų9326.1 Ų26.146%0.45814%0.135SC..G310 helixtrans-68-15.5175.1-73.4176.655.900113.3V48 H149 E150 F152 D156V48-M154 HydrophobicContact CB-CG 3.92Å; V48-M154 HydrophobicContact CB-SD 4Å; V48-M154 HydrophobicContact CG1-CG 4.32Å; V48-M154 HydrophobicContact CG1-SD 3.81Å; V48-M154 HydrophobicContact CG2-SD 4.48Å; H149-M154 WeakPolarHBondContact O-CB 3.45Å; H149-M154 WeakPolarHBondContact O-CG 3.32Å; H149-M154 PolarHBondContact O-N 2.94Å; E150-M154 HydrophobicContact CG-SD 4.39Å; F152-M154 PolarHBondContact O-N 3.45Å; M154-D156 VanDerWaalsContact C-N 3.31Å
155E97.5Very high97.7Very high94 Ų9422.8 Ų22.844%0.43912%0.117SC..G310 helixtrans-98.826.1176.2-68.6-73.9164.500110.6F152 A153 V157 I518 K522F152-E155 CarbonylContact O-C 3.1Å; F152-E155 WeakPolarHBondContact O-CA 3.33Å; F152-E155 WeakPolarHBondContact O-CB 3.46Å; F152-E155 PolarHBondContact O-N 3Å; A153-E155 PolarHBondContact O-N 2.93Å; E155-V157 VanDerWaalsContact C-N 3.25Å; E155-V157 PolarHBondContact O-N 3.3Å; E155-I518 HydrophobicContact CB-CD1 3.83Å; E155-I518 HydrophobicContact CB-CG1 4.38Å; E155-I518 HydrophobicContact CB-CG2 4.18Å; E155-I518 HydrophobicContact CG-CD1 3.69Å; E155-K522 WeakPolarHBondContact O-CE 3.17Å; E155-K522 PolarHBondContact O-NZ 3Å
156D97.1Very high97.7Very high55 Ų5521.6 Ų21.629%0.29411%0.109SC..THydrogen-bonded Turntrans5537178.3-46.3-45.7000113.4N117 C124 P125 A153 M154 K522N117-D156 WeakPolarHBondContact CB-OD1 3.3Å; N117-D156 PolarHBondContact ND2-OD1 3.41Å; C124-D156 VanDerWaalsContact CB-O 3.29Å; C124-D156 WeakPolarHBondContact CB-O 3.14Å; C124-D156 PolarHBondContact SG-O 3.14Å; P125-D156 WeakPolarHBondContact CD-O 3.32Å; A153-D156 PolarHBondContact O-N 2.89Å; M154-D156 VanDerWaalsContact C-N 3.31Å; D156-K522 IonicContact OD2-NZ 2.77Å
157V98.7Very high97.6Very high0 Ų018.4 Ų18.40%09%0.093CC..  trans-120.3122.4173.81770000108.9P125 V127 F152 A153 E155 F159 I518 V521P125-V157 HydrophobicContact CG-CG2 4.24Å; V127-V157 HydrophobicContact CB-CG1 4.4Å; V127-V157 HydrophobicContact CG2-CG1 3.66Å; F152-V157 CarbonylContact C-O 3.46Å; F152-V157 HydrophobicContact CB-CB 4.35Å; F152-V157 HydrophobicContact CD1-CG1 4.41Å; F152-V157 WeakPolarHBondContact O-CB 3.37Å; F152-V157 PolarHBondContact O-N 3.16Å; F152-V157 VanDerWaalsContact O-N 3.1Å; A153-V157 WeakPolarHBondContact CA-O 3.08Å; E155-V157 VanDerWaalsContact C-N 3.25Å; E155-V157 PolarHBondContact O-N 3.3Å; V157-F159 PolarHBondContact O-N 3.1Å; V157-I518 HydrophobicContact CG2-CG2 4.25Å; V157-V521 HydrophobicContact CG1-CG1 3.91Å; V157-V521 HydrophobicContact CG2-CG1 4.12Å
158I98.8Very high97.5Very high0 Ų017.4 Ų17.40%09%0.087CC..EExtended strand (participates in β ladder)trans-76.1122.6170.1-64.3-168.5000108.5V112 F113 A114 C118 C124 P125 V126 V127 V160 I199 F202 G204V112-I158 HydrophobicContact CG1-CG2 3.84Å; F113-I158 WeakPolarHBondContact O-CA 3.46Å; A114-I158 HydrophobicContact CB-CD1 3.88Å; A114-I158 HydrophobicContact CB-CG1 3.92Å; C118-I158 HydrophobicContact CB-CD1 4.19Å; C118-I158 HydrophobicContact CB-CG1 4.16Å; C124-I158 HydrophobicContact CB-CG1 4.06Å; P125-I158 PolarHBondContact O-N 3.18Å; V126-I158 CarbonylContact C-O 3.52Å; V126-I158 WeakPolarHBondContact CA-O 3.33Å; V126-I158 HydrophobicContact CG1-CG2 4.48Å; V126-I158 HydrophobicContact CG2-CB 4.35Å; V127-I158 PolarHBondContact N-O 3.05Å; I158-V160 HydrophobicContact CG2-CG2 4.13Å; I158-I199 HydrophobicContact CG2-CD1 4.01Å; I158-I199 HydrophobicContact CG2-CG1 4.47Å; I158-F202 HydrophobicContact CD1-CB 4.14Å; I158-F202 WeakPolarHBondContact CD1-O 3.43Å; I158-G204 VanDerWaalsContact CD1-CA 3.42Å; I158-G204 VanDerWaalsContact CD1-N 3.29Å
159F98.9Very high97.4Very high0 Ų017.8 Ų17.80%09%0.088CC..EExtended strand (participates in β ladder)trans-104.3131177.5-154-92.8000109.5F113 V127 F129 I148 F152 V157 T161 M212 L495F113-F159 HydrophobicContact CB-CB 4.42Å; F113-F159 HydrophobicContact CD2-CB 4.49Å; F113-F159 VanDerWaalsContact CD2-O 3.32Å; F113-F159 WeakPolarHBondContact CD2-O 3.25Å; F113-F159 PolarHBondContact N-O 3.22Å; F113-F159 PolarHBondContact O-N 2.96Å; V127-F159 HydrophobicContact CB-CD2 3.76Å; V127-F159 HydrophobicContact CB-CE2 3.99Å; V127-F159 HydrophobicContact CG1-CD2 3.83Å; V127-F159 HydrophobicContact CG1-CE2 3.51Å; V127-F159 HydrophobicContact CG1-CZ 4.18Å; V127-F159 HydrophobicContact CG2-CD2 4.44Å; F129-F159 HydrophobicContact CB-CD1 4.44Å; F129-F159 HydrophobicContact CB-CE1 3.44Å; F129-F159 VanDerWaalsContact CB-CE1 3.44Å; F129-F159 HydrophobicContact CB-CE2 4.47Å; F129-F159 HydrophobicContact CB-CZ 3.47Å; F129-F159 VanDerWaalsContact CB-CZ 3.47Å; F129-F159 AromaticContact CD2-CZ 3.88Å; F129-F159 HydrophobicContact CD2-CZ 3.88Å; F129-F159 AromaticContact CG-CE1 3.95Å; F129-F159 HydrophobicContact CG-CE1 3.95Å; F129-F159 AromaticContact CG-CZ 3.77Å; F129-F159 HydrophobicContact CG-CZ 3.77Å; I148-F159 HydrophobicContact CD1-CD1 4.4Å; I148-F159 HydrophobicContact CG2-CB 3.6Å; I148-F159 HydrophobicContact CG2-CD1 3.78Å; I148-F159 HydrophobicContact CG2-CG 3.83Å; F152-F159 HydrophobicContact CB-CB 4.13Å; F152-F159 HydrophobicContact CB-CD2 3.94Å; F152-F159 HydrophobicContact CB-CG 4.35Å; F152-F159 AromaticContact CD1-CD2 3.63Å; F152-F159 HydrophobicContact CD1-CD2 3.63Å; F152-F159 AromaticContact CD1-CE2 3.86Å; F152-F159 HydrophobicContact CD1-CE2 3.86Å; F152-F159 AromaticContact CD2-CD2 3.76Å; F152-F159 HydrophobicContact CD2-CD2 3.76Å; F152-F159 AromaticContact CD2-CE2 3.9Å; F152-F159 HydrophobicContact CD2-CE2 3.9Å; F152-F159 HydrophobicContact CD2-CG 4.37Å; F152-F159 HydrophobicContact CE1-CD2 4.04Å; F152-F159 AromaticContact CE1-CE2 3.75Å; F152-F159 HydrophobicContact CE1-CE2 3.75Å; F152-F159 HydrophobicContact CE2-CD2 4.17Å; F152-F159 AromaticContact CE2-CE2 3.81Å; F152-F159 HydrophobicContact CE2-CE2 3.81Å; F152-F159 HydrophobicContact CE2-CZ 4.35Å; F152-F159 AromaticContact CG-CD2 3.48Å; F152-F159 HydrophobicContact CG-CD2 3.48Å; F152-F159 VanDerWaalsContact CG-CD2 3.48Å; F152-F159 AromaticContact CG-CE2 3.93Å; F152-F159 HydrophobicContact CG-CE2 3.93Å; F152-F159 HydrophobicContact CG-CG 4.25Å; F152-F159 HydrophobicContact CZ-CD2 4.29Å; F152-F159 AromaticContact CZ-CE2 3.73Å; F152-F159 HydrophobicContact CZ-CE2 3.73Å; F152-F159 HydrophobicContact CZ-CZ 4.47Å; V157-F159 PolarHBondContact O-N 3.1Å; F159-T161 HydrophobicContact CD1-CG2 3.98Å; F159-T161 HydrophobicContact CE1-CG2 3.8Å; F159-M212 HydrophobicContact CE2-SD 4.39Å; F159-L495 HydrophobicContact CE1-CD2 4Å; F159-L495 HydrophobicContact CE2-CD2 4.38Å; F159-L495 HydrophobicContact CZ-CD1 4.48Å; F159-L495 HydrophobicContact CZ-CD2 3.67Å
160V98.9Very high97.4Very high0 Ų017.8 Ų17.80%09%0.088CC..EExtended strand (participates in β ladder)trans-122.8126.8179.1-173.30000108.9L110 N111 V112 V126 V127 F129 I158 V162 I195 I199L110-V160 HydrophobicContact CB-CG1 4.25Å; L110-V160 HydrophobicContact CD1-CG1 4.18Å; N111-V160 CarbonylContact O-C 3.58Å; N111-V160 VanDerWaalsContact O-CA 3.23Å; N111-V160 WeakPolarHBondContact O-CA 3.44Å; N111-V160 WeakPolarHBondContact O-CG1 3.23Å; V112-V160 HydrophobicContact CG2-CG1 4.38Å; V112-V160 HydrophobicContact CG2-CG2 4.22Å; V126-V160 HydrophobicContact CG1-CG2 3.95Å; V127-V160 PolarHBondContact O-N 2.9Å; F129-V160 PolarHBondContact N-O 3.47Å; I158-V160 HydrophobicContact CG2-CG2 4.13Å; V160-V162 HydrophobicContact CG1-CG2 4.35Å; V160-I195 HydrophobicContact CB-CD1 4.28Å; V160-I195 HydrophobicContact CG1-CD1 3.74Å; V160-I195 HydrophobicContact CG1-CG1 4.3Å; V160-I199 HydrophobicContact CG2-CD1 3.98Å
161T98.8Very high97.3Very high0 Ų013.6 Ų13.60%07%0.069CC..EExtended strand (participates in β ladder)trans-109.2133.4173.956.40000109.9L110 N111 F113 F129 F143 I148 F159L110-T161 CarbonylContact C-O 3.6Å; L110-T161 VanDerWaalsContact CA-O 3.25Å; L110-T161 WeakPolarHBondContact CA-O 3.43Å; L110-T161 WeakPolarHBondContact CB-O 3.44Å; N111-T161 WeakPolarHBondContact CB-OG1 3.44Å; N111-T161 PolarHBondContact N-O 3.08Å; N111-T161 PolarHBondContact ND2-O 2.9Å; N111-T161 PolarHBondContact ND2-OG1 3.1Å; N111-T161 PolarHBondContact O-N 3.19Å; F113-T161 HydrophobicContact CE2-CG2 4.29Å; F129-T161 HydrophobicContact CB-CG2 4.4Å; F143-T161 HydrophobicContact CD2-CG2 4.15Å; I148-T161 HydrophobicContact CD1-CG2 4.26Å; F159-T161 HydrophobicContact CD1-CG2 3.98Å; F159-T161 HydrophobicContact CE1-CG2 3.8Å
162V98.8Very high97.2Very high1 Ų113.2 Ų13.21%0.0067%0.067CC..EExtended strand (participates in β ladder)trans-116.8126.6-172.9178.60000110.1Y57 L110 I128 F129 I130 P140 V160 A191 I195Y57-V162 HydrophobicContact CE1-CG1 4.18Å; L110-V162 HydrophobicContact CB-CG2 4.18Å; I128-V162 HydrophobicContact CG2-CG2 3.76Å; F129-V162 PolarHBondContact O-N 3.07Å; I130-V162 HydrophobicContact CD1-CB 4.13Å; I130-V162 HydrophobicContact CD1-CG2 4.47Å; P140-V162 VanDerWaalsContact CG-C 3.43Å; P140-V162 WeakPolarHBondContact CG-O 3.46Å; V160-V162 HydrophobicContact CG1-CG2 4.35Å; V162-A191 HydrophobicContact CB-CB 4.43Å; V162-A191 HydrophobicContact CG1-CB 3.53Å; V162-A191 HydrophobicContact CG2-CB 3.97Å; V162-I195 HydrophobicContact CG2-CD1 4.48Å
163A98.3Very high96.8Very high7 Ų713.1 Ų13.16%0.0587%0.067CC..  trans-87.8142.2165.100000108.7Y57 C107 Y109 P140Y57-A163 PolarHBondContact OH-O 3.36Å; C107-A163 VanDerWaalsContact O-CB 3.28Å; C107-A163 WeakPolarHBondContact O-CB 3.4Å; Y109-A163 WeakPolarHBondContact O-CB 3.34Å; Y109-A163 PolarHBondContact O-N 2.93Å; Y109-A163 VanDerWaalsContact O-N 3.1Å; P140-A163 HydrophobicContact CG-CB 3.96Å
164Y98.6Very high96.4Very high0 Ų014.3 Ų14.30%07%0.074CC..  trans-144.7154.9-179.561.7-86.3000109.7C90 I130 H131 F135 L166 I188C90-Y164 PolarHBondContact SG-O 2.93Å; I130-Y164 HydrophobicContact CG2-CD1 4.28Å; I130-Y164 HydrophobicContact CG2-CE1 3.69Å; H131-Y164 AromaticContact CD2-CE1 3.77Å; H131-Y164 AromaticContact CE1-CE1 3.7Å; H131-Y164 AromaticContact NE2-CD1 3.87Å; H131-Y164 AromaticContact NE2-CE1 3.5Å; H131-Y164 PolarHBondContact O-OH 3.12Å; H131-Y164 VanDerWaalsContact O-OH 3.06Å; F135-Y164 HydrophobicContact CD1-CE2 4.42Å; Y164-L166 HydrophobicContact CD2-CD2 4.04Å; Y164-L166 HydrophobicContact CE2-CD2 3.44Å; Y164-L166 VanDerWaalsContact CE2-CD2 3.44Å; Y164-L166 WeakPolarHBondContact O-CG 3.29Å; Y164-L166 PolarHBondContact O-N 3.25Å; Y164-I188 HydrophobicContact CD1-CD1 4.1Å; Y164-I188 HydrophobicContact CD1-CG1 4.06Å; Y164-I188 HydrophobicContact CD2-CD1 4.16Å; Y164-I188 HydrophobicContact CD2-CG1 4.44Å; Y164-I188 HydrophobicContact CE1-CD1 4.39Å; Y164-I188 HydrophobicContact CE2-CD1 4.45Å; Y164-I188 HydrophobicContact CG-CD1 3.99Å; Y164-I188 HydrophobicContact CG-CG1 3.87Å
165R98.2Very high95.8Very high7 Ų712.4 Ų12.43%0.0267%0.073CC..  trans-60.6138.3-177.3-76.6172.7-75.1179.5-6111.8P61 A68 L108 G170 G184 D187P61-R165 HydrophobicContact CG-CG 4.24Å; A68-R165 PolarHBondContact O-NH1 2.52Å; A68-R165 PolarHBondContact O-NH2 3.13Å; L108-R165 HydrophobicContact CD2-CG 4.13Å; R165-G170 VanDerWaalsContact CB-CA 3.49Å; R165-G184 WeakPolarHBondContact O-CA 3.46Å; R165-D187 WeakPolarHBondContact CB-OD2 3.28Å; R165-D187 VanDerWaalsContact CG-OD2 3.22Å; R165-D187 WeakPolarHBondContact CG-OD2 3.27Å; R165-D187 IonicContact CZ-OD1 2.64Å; R165-D187 IonicContact CZ-OD2 2.74Å; R165-D187 PolarHBondContact N-OD2 2.69Å; R165-D187 IonicContact NE-OD1 3.55Å; R165-D187 PolarHBondContact NE-OD1 3.39Å; R165-D187 IonicContact NE-OD2 2.98Å; R165-D187 PolarHBondContact NE-OD2 2.93Å; R165-D187 IonicContact NH2-OD1 3.53Å; R165-D187 PolarHBondContact NH2-OD1 3.07Å; R165-D187 IonicContact NH2-OD2 2.74Å
166L95.6Very high95.3Very high1 Ų19 Ų91%0.0056%0.059CC..  trans-116.5164.2-176.3-60.4170.1000111C90 F135 Y164 F169 G170C90-L166 HydrophobicContact CB-CD1 4.29Å; C90-L166 HydrophobicContact CB-CG 4.3Å; F135-L166 CarbonylContact O-C 3.52Å; F135-L166 VanDerWaalsContact O-CA 3.3Å; F135-L166 WeakPolarHBondContact O-CA 3.28Å; F135-L166 WeakPolarHBondContact O-CB 3.06Å; F135-L166 WeakPolarHBondContact O-CD2 3.45Å; Y164-L166 HydrophobicContact CD2-CD2 4.04Å; Y164-L166 HydrophobicContact CE2-CD2 3.44Å; Y164-L166 VanDerWaalsContact CE2-CD2 3.44Å; Y164-L166 WeakPolarHBondContact O-CG 3.29Å; Y164-L166 PolarHBondContact O-N 3.25Å; L166-F169 WeakPolarHBondContact O-CB 3.49Å; L166-F169 PolarHBondContact O-N 2.94Å; L166-F169 VanDerWaalsContact O-N 3.13Å; L166-G170 PolarHBondContact O-N 2.84Å
167G93.1Very high94.8Very high5 Ų513.4 Ų13.45%0.0528%0.082CC..Hα-helixtrans51.9-139.6175.400000113.2F135 D136 F169 G170 F171 T338F135-G167 PolarHBondContact O-N 2.66Å; D136-G167 WeakPolarHBondContact OD1-CA 3.38Å; G167-F169 PolarHBondContact O-N 3.23Å; G167-G170 PolarHBondContact O-N 3.1Å; G167-G170 VanDerWaalsContact O-N 3.12Å; G167-F171 WeakPolarHBondContact O-CD2 3.15Å; G167-F171 PolarHBondContact O-N 3.01Å; G167-T338 VanDerWaalsContact C-CG2 3.44Å
168V93.9Very high94.3Very high1 Ų116.6 Ų16.61%0.00610%0.097CC..Hα-helixtrans-56.5-35.7177.161.60000112.4F67 G170 F171 F172 L260 L292 Y296F67-V168 HydrophobicContact CE1-CG2 4.44Å; F67-V168 WeakPolarHBondContact CE1-O 3.22Å; V168-G170 VanDerWaalsContact C-N 3.3Å; V168-G170 PolarHBondContact O-N 2.91Å; V168-F171 PolarHBondContact O-N 2.85Å; V168-F172 HydrophobicContact CG2-CB 3.95Å; V168-F172 HydrophobicContact CG2-CD2 4.38Å; V168-F172 WeakPolarHBondContact O-CB 3.37Å; V168-F172 PolarHBondContact O-N 3.31Å; V168-L260 HydrophobicContact CB-CD2 4.38Å; V168-L260 HydrophobicContact CG2-CD2 3.68Å; V168-L292 HydrophobicContact CG1-CD1 4.29Å; V168-L292 HydrophobicContact CG1-CD2 3.98Å; V168-L292 HydrophobicContact CG1-CG 3.78Å; V168-L292 HydrophobicContact CG2-CD1 4.01Å; V168-L292 HydrophobicContact CG2-CD2 4.35Å; V168-L292 HydrophobicContact CG2-CG 4.33Å; V168-Y296 HydrophobicContact CB-CD2 3.62Å; V168-Y296 HydrophobicContact CB-CE2 4.08Å; V168-Y296 HydrophobicContact CB-CG 4.01Å; V168-Y296 HydrophobicContact CG1-CD2 4.19Å; V168-Y296 HydrophobicContact CG1-CG 4.06Å; V168-Y296 HydrophobicContact CG2-CD2 4.4Å
169F96.4Very high93.9Very high9 Ų916.6 Ų16.64%0.03910%0.097CC..Hα-helixtrans-66.1-32.8179.6-56.5-85.9000112.7W91 E105 L166 G167 A289 L292 D293W91-F169 HydrophobicContact CB-CD2 3.96Å; W91-F169 HydrophobicContact CB-CE2 3.8Å; W91-F169 HydrophobicContact CB-CZ 4.21Å; W91-F169 AromaticContact CD1-CE2 3.34Å; W91-F169 AromaticContact CD1-CZ 3.75Å; W91-F169 HydrophobicContact CD2-CZ 4.47Å; W91-F169 HydrophobicContact CG-CD2 4.32Å; W91-F169 AromaticContact CG-CE2 3.66Å; W91-F169 HydrophobicContact CG-CE2 3.66Å; W91-F169 AromaticContact CG-CZ 3.86Å; W91-F169 HydrophobicContact CG-CZ 3.86Å; E105-F169 HydrophobicContact CG-CD1 4.11Å; E105-F169 HydrophobicContact CG-CE1 4.02Å; E105-F169 WeakPolarHBondContact OE1-CD1 3.39Å; E105-F169 WeakPolarHBondContact OE1-CE1 3.48Å; L166-F169 WeakPolarHBondContact O-CB 3.49Å; L166-F169 PolarHBondContact O-N 2.94Å; L166-F169 VanDerWaalsContact O-N 3.13Å; G167-F169 PolarHBondContact O-N 3.23Å; F169-A289 HydrophobicContact CE1-CB 3.87Å; F169-A289 HydrophobicContact CZ-CB 3.73Å; F169-L292 HydrophobicContact CD1-CD2 4.24Å; F169-L292 HydrophobicContact CE1-CD2 3.65Å; F169-L292 HydrophobicContact CZ-CB 4.44Å; F169-L292 HydrophobicContact CZ-CD2 3.86Å; F169-L292 HydrophobicContact CZ-CG 4.29Å; F169-D293 HydrophobicContact CE2-CB 4.17Å
170G96.7Very high93.4Very high0 Ų019.6 Ų19.60%011%0.111CC..Hα-helixtrans-89.2-24.7179.400000114.7R165 L166 G167 V168 F183 G184R165-G170 VanDerWaalsContact CB-CA 3.49Å; L166-G170 PolarHBondContact O-N 2.84Å; G167-G170 PolarHBondContact O-N 3.1Å; G167-G170 VanDerWaalsContact O-N 3.12Å; V168-G170 VanDerWaalsContact C-N 3.3Å; V168-G170 PolarHBondContact O-N 2.91Å; G170-F183 CarbonylContact O-C 3.59Å; G170-F183 WeakPolarHBondContact O-CA 3.41Å; G170-F183 VanDerWaalsContact O-CB 3.32Å; G170-F183 WeakPolarHBondContact O-CB 3.38Å; G170-F183 PolarHBondContact O-N 3.43Å; G170-G184 PolarHBondContact O-N 3.3Å
171F95.3Very high93.1Very high2 Ų219.8 Ų19.81%0.00911%0.113CC..Hα-helixtrans-137.12.5-164.8-60-78.6000115.5F135 G167 V168 S173 L185 Y257 T338 P340F135-F171 HydrophobicContact CB-CD2 4.25Å; F135-F171 HydrophobicContact CB-CE2 3.68Å; F135-F171 HydrophobicContact CB-CZ 4.19Å; F135-F171 AromaticContact CD1-CE2 3.97Å; F135-F171 HydrophobicContact CD1-CE2 3.97Å; F135-F171 AromaticContact CD1-CZ 3.63Å; F135-F171 HydrophobicContact CD1-CZ 3.63Å; F135-F171 HydrophobicContact CE1-CZ 4.31Å; F135-F171 HydrophobicContact CG-CE2 4.15Å; F135-F171 HydrophobicContact CG-CZ 4.16Å; G167-F171 WeakPolarHBondContact O-CD2 3.15Å; G167-F171 PolarHBondContact O-N 3.01Å; V168-F171 PolarHBondContact O-N 2.85Å; F171-S173 PolarHBondContact O-N 2.8Å; F171-L185 HydrophobicContact CE1-CG 4.37Å; F171-Y257 WeakPolarHBondContact CB-OH 3.42Å; F171-Y257 WeakPolarHBondContact O-CE2 3.48Å; F171-Y257 PolarHBondContact O-OH 3.04Å; F171-Y257 VanDerWaalsContact O-OH 3.04Å; F171-T338 HydrophobicContact CB-CG2 4.34Å; F171-P340 HydrophobicContact CD1-CG 4.48Å; F171-P340 HydrophobicContact CE1-CB 4.39Å; F171-P340 HydrophobicContact CE1-CG 3.79Å; F171-P340 HydrophobicContact CZ-CG 4.44Å
172F93.9Very high93Very high1 Ų119.9 Ų19.90%0.00411%0.113CC..  trans-52.2132.2171.5174.1-105.6000111F67 V168 T174 A179 G181 F183 Y257 V281 M284F67-F172 HydrophobicContact CB-CD1 4.13Å; F67-F172 HydrophobicContact CD1-CB 3.65Å; F67-F172 AromaticContact CD1-CD1 3.78Å; F67-F172 HydrophobicContact CD1-CD1 3.78Å; F67-F172 HydrophobicContact CD1-CG 4.07Å; F67-F172 AromaticContact CD2-CD1 3.84Å; F67-F172 HydrophobicContact CD2-CD1 3.84Å; F67-F172 HydrophobicContact CD2-CE1 4.23Å; F67-F172 HydrophobicContact CE1-CB 3.57Å; F67-F172 HydrophobicContact CE1-CD1 4.08Å; F67-F172 HydrophobicContact CE1-CG 4.02Å; F67-F172 HydrophobicContact CE2-CD1 4.15Å; F67-F172 HydrophobicContact CG-CB 4.4Å; F67-F172 AromaticContact CG-CD1 3.64Å; F67-F172 HydrophobicContact CG-CD1 3.64Å; F67-F172 HydrophobicContact CG-CE1 4.4Å; F67-F172 HydrophobicContact CG-CG 4.38Å; F67-F172 HydrophobicContact CZ-CB 4.27Å; F67-F172 HydrophobicContact CZ-CD1 4.24Å; F67-F172 HydrophobicContact CZ-CG 4.28Å; V168-F172 HydrophobicContact CG2-CB 3.95Å; V168-F172 HydrophobicContact CG2-CD2 4.38Å; V168-F172 WeakPolarHBondContact O-CB 3.37Å; V168-F172 PolarHBondContact O-N 3.31Å; F172-T174 HydrophobicContact CE1-CG2 4.14Å; F172-T174 HydrophobicContact CZ-CG2 3.85Å; F172-A179 HydrophobicContact CD1-CB 4.01Å; F172-A179 HydrophobicContact CE1-CB 3.84Å; F172-G181 VanDerWaalsContact O-CA 3.3Å; F172-G181 WeakPolarHBondContact O-CA 3.46Å; F172-F183 WeakPolarHBondContact O-CE2 3.14Å; F172-Y257 AromaticContact CD2-CD1 3.92Å; F172-Y257 HydrophobicContact CD2-CD1 3.92Å; F172-Y257 AromaticContact CD2-CG 4Å; F172-Y257 HydrophobicContact CD2-CG 4Å; F172-V281 HydrophobicContact CE1-CG2 4.41Å; F172-M284 HydrophobicContact CD2-CE 4.09Å; F172-M284 HydrophobicContact CE1-CB 4.41Å; F172-M284 HydrophobicContact CE1-CG 4.38Å; F172-M284 HydrophobicContact CE2-CE 3.75Å; F172-M284 HydrophobicContact CE2-CG 4.3Å; F172-M284 HydrophobicContact CZ-CB 4.33Å; F172-M284 HydrophobicContact CZ-CE 4.2Å; F172-M284 HydrophobicContact CZ-CG 3.82Å
173S90.8Very high92.9Very high0 Ų020 Ų200%011%0.114CC..  trans-145.5139.5-178.8-175.70000111.3F171 A175 A179 E180 R341F171-S173 PolarHBondContact O-N 2.8Å; S173-A175 PolarHBondContact OG-N 3.37Å; S173-A179 WeakPolarHBondContact CA-O 3.42Å; S173-A179 PolarHBondContact OG-O 3.42Å; S173-E180 PolarHBondContact OG-O 2.65Å; S173-R341 WeakPolarHBondContact OG-CD 3.09Å
174T88.6Confident92.9Very high25 Ų2519.7 Ų19.715%0.15311%0.111CC..  trans-103.87165.552.40000111.9F172 S176 A179 I277 V281F172-T174 HydrophobicContact CE1-CG2 4.14Å; F172-T174 HydrophobicContact CZ-CG2 3.85Å; T174-S176 PolarHBondContact O-N 2.72Å; T174-S176 PolarHBondContact OG1-OG 3.4Å; T174-A179 HydrophobicContact CG2-CB 4.41Å; T174-A179 PolarHBondContact N-O 2.95Å; T174-A179 PolarHBondContact OG1-O 3.42Å; T174-I277 HydrophobicContact CG2-CG2 4.06Å; T174-V281 HydrophobicContact CG2-CG2 4.01Å
175A85Confident92.9Very high53 Ų5319.8 Ų19.844%0.43811%0.112SC..SBendtrans4936.4-170.400000113S173 I254S173-A175 PolarHBondContact OG-N 3.37Å; A175-I254 HydrophobicContact CB-CD1 3.88Å; A175-I254 HydrophobicContact CB-CG2 4.26Å
176S86.1Confident92.9Very high21 Ų2120 Ų2015%0.14711%0.114CC..BIsolated β-bridgetrans-135.8165.7177.777.30000110.1T174 E178 A179 E180 I277T174-S176 PolarHBondContact O-N 2.72Å; T174-S176 PolarHBondContact OG1-OG 3.4Å; S176-E178 WeakPolarHBondContact CB-OE2 3.3Å; S176-E178 PolarHBondContact O-N 3.34Å; S176-E178 VanDerWaalsContact O-N 3.14Å; S176-E178 PolarHBondContact OG-OE2 3.21Å; S176-A179 CarbonylContact O-C 3.53Å; S176-A179 PolarHBondContact O-N 2.7Å; S176-A179 VanDerWaalsContact O-N 3.11Å; S176-E180 WeakPolarHBondContact O-CA 3.24Å; S176-E180 VanDerWaalsContact O-CG 3.25Å; S176-E180 WeakPolarHBondContact O-CG 3.3Å; S176-E180 PolarHBondContact O-N 3.13Å; S176-E180 VanDerWaalsContact O-N 3.12Å; S176-I277 VanDerWaalsContact OG-CG2 3.23Å; S176-I277 WeakPolarHBondContact OG-CG2 3.26Å
177L87.1Confident93.1Very high149 Ų14919.9 Ų19.978%0.7811%0.114SC*.THydrogen-bonded Turntrans-60.3-24-179-62.6178.4000113.3E180L177-E180 VanDerWaalsContact CD2-OE1 3.24Å; L177-E180 WeakPolarHBondContact CD2-OE1 3.22Å
178E87.8Confident93.4Very high66 Ų6619.7 Ų19.731%0.30811%0.111SC..THydrogen-bonded Turntrans-72.7-29.1178.5-60.392.3156.200113.4S176 S278 V281S176-E178 WeakPolarHBondContact CB-OE2 3.3Å; S176-E178 PolarHBondContact O-N 3.34Å; S176-E178 VanDerWaalsContact O-N 3.14Å; S176-E178 PolarHBondContact OG-OE2 3.21Å; E178-S278 PolarHBondContact OE1-OG 3.33Å; E178-V281 HydrophobicContact CB-CB 4.34Å; E178-V281 HydrophobicContact CB-CG2 3.86Å
179A90.2Very high93.6Very high1 Ų119.9 Ų19.91%0.00811%0.113CC..BIsolated β-bridgetrans-154.183.7173.500000110.6F67 F172 S173 T174 S176 G181 F183 V281F67-A179 HydrophobicContact CB-CB 4.47Å; F172-A179 HydrophobicContact CD1-CB 4.01Å; F172-A179 HydrophobicContact CE1-CB 3.84Å; S173-A179 WeakPolarHBondContact CA-O 3.42Å; S173-A179 PolarHBondContact OG-O 3.42Å; T174-A179 HydrophobicContact CG2-CB 4.41Å; T174-A179 PolarHBondContact N-O 2.95Å; T174-A179 PolarHBondContact OG1-O 3.42Å; S176-A179 CarbonylContact O-C 3.53Å; S176-A179 PolarHBondContact O-N 2.7Å; S176-A179 VanDerWaalsContact O-N 3.11Å; A179-G181 VanDerWaalsContact C-N 3.29Å; A179-G181 PolarHBondContact O-N 2.75Å; A179-F183 HydrophobicContact CB-CZ 4.36Å; A179-V281 HydrophobicContact CB-CG1 4.22Å; A179-V281 HydrophobicContact CB-CG2 3.69Å
180E89.5Confident93.7Very high63 Ų6320 Ų2029%0.29411%0.113SC..  trans-70.1-27.4-175.4-65.1-178.7133.200112.5S173 S176 L177 R341S173-E180 PolarHBondContact OG-O 2.65Å; S176-E180 WeakPolarHBondContact O-CA 3.24Å; S176-E180 VanDerWaalsContact O-CG 3.25Å; S176-E180 WeakPolarHBondContact O-CG 3.3Å; S176-E180 PolarHBondContact O-N 3.13Å; S176-E180 VanDerWaalsContact O-N 3.12Å; L177-E180 VanDerWaalsContact CD2-OE1 3.24Å; L177-E180 WeakPolarHBondContact CD2-OE1 3.22Å; E180-R341 WeakPolarHBondContact O-CD 3.45Å; E180-R341 PolarHBondContact O-NH1 2.79Å
181G92.2Very high93.8Very high4 Ų420 Ų204%0.04111%0.113CC..SBendtrans91.4-164.1-171.100000111.6F172 A179 F183F172-G181 VanDerWaalsContact O-CA 3.3Å; F172-G181 WeakPolarHBondContact O-CA 3.46Å; A179-G181 VanDerWaalsContact C-N 3.29Å; A179-G181 PolarHBondContact O-N 2.75Å; G181-F183 PolarHBondContact O-N 3.09Å
182N96.1Very high94Very high1 Ų120 Ų201%0.00511%0.113CC..  trans54.416.5-178.4-71.2-17.2000116G184 L185 S186 P340 R341 D343 I348N182-G184 PolarHBondContact O-N 2.96Å; N182-G184 VanDerWaalsContact O-N 3.17Å; N182-L185 HydrophobicContact CB-CB 4.46Å; N182-L185 CarbonylContact O-C 3.58Å; N182-L185 WeakPolarHBondContact O-CA 3.47Å; N182-L185 WeakPolarHBondContact O-CB 3.28Å; N182-L185 PolarHBondContact O-N 3.33Å; N182-S186 PolarHBondContact O-N 3.31Å; N182-S186 PolarHBondContact O-OG 3.05Å; N182-P340 WeakPolarHBondContact OD1-CA 3.32Å; N182-R341 PolarHBondContact ND2-O 2.94Å; N182-R341 PolarHBondContact OD1-N 3.3Å; N182-D343 PolarHBondContact ND2-OD2 3.39Å; N182-I348 HydrophobicContact CB-CD1 4.08Å
183F97.8Very high94.2Very high5 Ų524.5 Ų24.52%0.02213%0.133CC..Hα-helixtrans-56.7-36.6-178.3-52.6-57.1000113.1F67 A68 G170 F172 A179 G181 L185 S186 D187F67-F183 VanDerWaalsContact C-CE1 3.44Å; F67-F183 HydrophobicContact CB-CD2 4.45Å; F67-F183 HydrophobicContact CB-CE2 3.65Å; F67-F183 HydrophobicContact CB-CZ 3.94Å; F67-F183 HydrophobicContact CD1-CD2 4.46Å; F67-F183 HydrophobicContact CD1-CE2 4.19Å; F67-F183 HydrophobicContact CG-CE2 4.4Å; F67-F183 WeakPolarHBondContact O-CE1 3.39Å; F67-F183 WeakPolarHBondContact O-CZ 3.46Å; A68-F183 VanDerWaalsContact C-CD1 3.46Å; A68-F183 WeakPolarHBondContact O-CD1 3.47Å; G170-F183 CarbonylContact O-C 3.59Å; G170-F183 WeakPolarHBondContact O-CA 3.41Å; G170-F183 VanDerWaalsContact O-CB 3.32Å; G170-F183 WeakPolarHBondContact O-CB 3.38Å; G170-F183 PolarHBondContact O-N 3.43Å; F172-F183 WeakPolarHBondContact O-CE2 3.14Å; A179-F183 HydrophobicContact CB-CZ 4.36Å; G181-F183 PolarHBondContact O-N 3.09Å; F183-L185 VanDerWaalsContact C-N 3.32Å; F183-L185 PolarHBondContact O-N 3.12Å; F183-S186 PolarHBondContact O-N 3.29Å; F183-D187 WeakPolarHBondContact O-CB 3.36Å; F183-D187 PolarHBondContact O-N 2.85Å
184G98.3Very high94.6Very high0 Ų024.5 Ų24.50%013%0.133CC..Hα-helixtrans-63.7-33.7173.200000113.3R165 G170 N182 I188R165-G184 WeakPolarHBondContact O-CA 3.46Å; G170-G184 PolarHBondContact O-N 3.3Å; N182-G184 PolarHBondContact O-N 2.96Å; N182-G184 VanDerWaalsContact O-N 3.17Å; G184-I188 WeakPolarHBondContact O-CG1 3.48Å; G184-I188 PolarHBondContact O-N 3.13Å
185L98.7Very high95.1Very high1 Ų123.3 Ų23.31%0.00513%0.126CC..Hα-helixtrans-74.4-39.8171.6-65.8-171.9000111.4F171 N182 F183 D187 I188 I189 A220 P340 I348 L349F171-L185 HydrophobicContact CE1-CG 4.37Å; N182-L185 HydrophobicContact CB-CB 4.46Å; N182-L185 CarbonylContact O-C 3.58Å; N182-L185 WeakPolarHBondContact O-CA 3.47Å; N182-L185 WeakPolarHBondContact O-CB 3.28Å; N182-L185 PolarHBondContact O-N 3.33Å; F183-L185 VanDerWaalsContact C-N 3.32Å; F183-L185 PolarHBondContact O-N 3.12Å; L185-D187 PolarHBondContact O-N 3.42Å; L185-I188 HydrophobicContact CD2-CD1 4.25Å; L185-I188 PolarHBondContact O-N 3.02Å; L185-I188 VanDerWaalsContact O-N 3.15Å; L185-I189 WeakPolarHBondContact O-CG1 3.15Å; L185-I189 PolarHBondContact O-N 2.85Å; L185-A220 HydrophobicContact CD2-CB 3.96Å; L185-P340 HydrophobicContact CD1-CB 3.73Å; L185-P340 HydrophobicContact CD1-CG 3.78Å; L185-P340 HydrophobicContact CD2-CG 4.19Å; L185-P340 HydrophobicContact CG-CB 4.4Å; L185-P340 HydrophobicContact CG-CG 4.02Å; L185-I348 HydrophobicContact CB-CD1 3.85Å; L185-I348 HydrophobicContact CB-CG2 4.37Å; L185-I348 HydrophobicContact CD1-CG2 4.08Å; L185-L349 HydrophobicContact CD1-CD1 4.3Å
186S98.5Very high95.7Very high11 Ų1123.2 Ų23.28%0.07712%0.115CC..Hα-helixtrans-59.3-37.9174.1-50.50000111.4P70 N182 F183 I189 E190 I348P70-S186 VanDerWaalsContact CD-CB 3.43Å; P70-S186 WeakPolarHBondContact CG-O 3.3Å; N182-S186 PolarHBondContact O-N 3.31Å; N182-S186 PolarHBondContact O-OG 3.05Å; F183-S186 PolarHBondContact O-N 3.29Å; S186-I189 PolarHBondContact O-N 2.95Å; S186-E190 WeakPolarHBondContact O-CB 3.49Å; S186-E190 PolarHBondContact O-N 3.2Å; S186-I348 WeakPolarHBondContact OG-CD1 3.4Å
187D98.9Very high96.3Very high0 Ų026.9 Ų26.90%013%0.126CC..Hα-helixtrans-60.6-44.4174.6-67.1-17.9000111.9Y57 P70 L108 R165 F183 L185 E190 A191Y57-D187 VanDerWaalsContact CE2-O 3.27Å; Y57-D187 WeakPolarHBondContact CE2-O 3.1Å; P70-D187 WeakPolarHBondContact CB-OD1 3.14Å; L108-D187 HydrophobicContact CD2-CB 4.12Å; L108-D187 WeakPolarHBondContact CD2-OD2 3.32Å; R165-D187 WeakPolarHBondContact CB-OD2 3.28Å; R165-D187 VanDerWaalsContact CG-OD2 3.22Å; R165-D187 WeakPolarHBondContact CG-OD2 3.27Å; R165-D187 IonicContact CZ-OD1 2.64Å; R165-D187 IonicContact CZ-OD2 2.74Å; R165-D187 PolarHBondContact N-OD2 2.69Å; R165-D187 IonicContact NE-OD1 3.55Å; R165-D187 PolarHBondContact NE-OD1 3.39Å; R165-D187 IonicContact NE-OD2 2.98Å; R165-D187 PolarHBondContact NE-OD2 2.93Å; R165-D187 IonicContact NH2-OD1 3.53Å; R165-D187 PolarHBondContact NH2-OD1 3.07Å; R165-D187 IonicContact NH2-OD2 2.74Å; F183-D187 WeakPolarHBondContact O-CB 3.36Å; F183-D187 PolarHBondContact O-N 2.85Å; L185-D187 PolarHBondContact O-N 3.42Å; D187-E190 PolarHBondContact O-N 3.26Å; D187-A191 PolarHBondContact O-N 3.28Å
188I98.9Very high96.8Very high0 Ų020 Ų200%09%0.09CC..Hα-helixtrans-63.5-44.7176-64.4165.4000110.2I130 Y164 G184 L185 E190 A191 M192 A220 L224I130-I188 HydrophobicContact CD1-CD1 4.43Å; I130-I188 HydrophobicContact CD1-CG1 4.19Å; I130-I188 HydrophobicContact CD1-CG2 3.65Å; I130-I188 HydrophobicContact CG1-CG2 4.23Å; I130-I188 HydrophobicContact CG2-CD1 3.71Å; I130-I188 HydrophobicContact CG2-CG1 4.48Å; Y164-I188 HydrophobicContact CD1-CD1 4.1Å; Y164-I188 HydrophobicContact CD1-CG1 4.06Å; Y164-I188 HydrophobicContact CD2-CD1 4.16Å; Y164-I188 HydrophobicContact CD2-CG1 4.44Å; Y164-I188 HydrophobicContact CE1-CD1 4.39Å; Y164-I188 HydrophobicContact CE2-CD1 4.45Å; Y164-I188 HydrophobicContact CG-CD1 3.99Å; Y164-I188 HydrophobicContact CG-CG1 3.87Å; G184-I188 WeakPolarHBondContact O-CG1 3.48Å; G184-I188 PolarHBondContact O-N 3.13Å; L185-I188 HydrophobicContact CD2-CD1 4.25Å; L185-I188 PolarHBondContact O-N 3.02Å; L185-I188 VanDerWaalsContact O-N 3.15Å; I188-E190 VanDerWaalsContact C-N 3.33Å; I188-E190 PolarHBondContact O-N 2.94Å; I188-A191 WeakPolarHBondContact O-CB 3.4Å; I188-A191 PolarHBondContact O-N 3.23Å; I188-M192 HydrophobicContact CG2-CG 4.41Å; I188-M192 HydrophobicContact CG2-SD 4.18Å; I188-M192 VanDerWaalsContact O-CG 3.29Å; I188-M192 WeakPolarHBondContact O-CG 3.05Å; I188-M192 PolarHBondContact O-N 3.32Å; I188-A220 HydrophobicContact CD1-CB 4.29Å; I188-L224 HydrophobicContact CB-CD1 4.2Å; I188-L224 HydrophobicContact CD1-CD1 4.5Å; I188-L224 HydrophobicContact CG2-CD1 3.51Å
189I98.9Very high97.3Very high6 Ų616.9 Ų16.93%0.0318%0.075CC..Hα-helixtrans-62.2-40.9178.4-67.3168.9000111L185 S186 M192 K193 L224 K229 T230 L233 I348L185-I189 WeakPolarHBondContact O-CG1 3.15Å; L185-I189 PolarHBondContact O-N 2.85Å; S186-I189 PolarHBondContact O-N 2.95Å; I189-M192 WeakPolarHBondContact O-CB 3.34Å; I189-M192 PolarHBondContact O-N 3.05Å; I189-K193 HydrophobicContact CG2-CD 4.4Å; I189-K193 WeakPolarHBondContact O-CG 3.43Å; I189-K193 PolarHBondContact O-N 3.3Å; I189-L224 HydrophobicContact CD1-CD2 3.79Å; I189-L224 HydrophobicContact CG1-CD2 3.67Å; I189-K229 HydrophobicContact CD1-CB 3.95Å; I189-T230 HydrophobicContact CD1-CG2 4.27Å; I189-T230 HydrophobicContact CG1-CG2 4Å; I189-L233 HydrophobicContact CG2-CD1 4.16Å; I189-I348 HydrophobicContact CD1-CB 4.47Å; I189-I348 HydrophobicContact CD1-CD1 3.78Å; I189-I348 HydrophobicContact CD1-CG1 3.71Å; I189-I348 HydrophobicContact CD1-CG2 3.94Å
190E98.9Very high97.7Very high12 Ų1220.9 Ų20.96%0.05610%0.096CC..Hα-helixtrans-66.1-39.2176.4-175.155.1-154.700111.9Y57 A58 P70 S72 S186 D187 I188 M192 K193 W194Y57-E190 HydrophobicContact CD2-CB 4.36Å; Y57-E190 HydrophobicContact CD2-CG 4.1Å; Y57-E190 HydrophobicContact CE2-CB 4.36Å; Y57-E190 HydrophobicContact CE2-CG 4.48Å; A58-E190 HydrophobicContact CB-CG 4.32Å; P70-E190 HydrophobicContact CB-CB 4.21Å; P70-E190 HydrophobicContact CB-CG 4.29Å; P70-E190 HydrophobicContact CG-CB 3.67Å; P70-E190 HydrophobicContact CG-CG 4.2Å; S72-E190 WeakPolarHBondContact CA-OE1 3.4Å; S72-E190 VanDerWaalsContact CB-OE1 3.24Å; S72-E190 WeakPolarHBondContact CB-OE1 3.31Å; S72-E190 PolarHBondContact OG-OE1 3.27Å; S186-E190 WeakPolarHBondContact O-CB 3.49Å; S186-E190 PolarHBondContact O-N 3.2Å; D187-E190 PolarHBondContact O-N 3.26Å; I188-E190 VanDerWaalsContact C-N 3.33Å; I188-E190 PolarHBondContact O-N 2.94Å; E190-M192 PolarHBondContact O-N 3.13Å; E190-K193 PolarHBondContact O-N 3.23Å; E190-W194 WeakPolarHBondContact O-CB 3.42Å; E190-W194 PolarHBondContact O-N 3.12Å
191A98.9Very high98.1Very high0 Ų020 Ų200%010%0.1CC..Hα-helixtrans-61.8-42171.200000111.7Y57 L110 V162 D187 I188 K193 W194 I195Y57-A191 HydrophobicContact CD1-CB 4.13Å; Y57-A191 HydrophobicContact CD2-CB 3.96Å; Y57-A191 HydrophobicContact CE1-CB 4.11Å; Y57-A191 HydrophobicContact CE2-CB 3.96Å; Y57-A191 HydrophobicContact CG-CB 4.04Å; L110-A191 HydrophobicContact CD2-CB 4.29Å; V162-A191 HydrophobicContact CB-CB 4.43Å; V162-A191 HydrophobicContact CG1-CB 3.53Å; V162-A191 HydrophobicContact CG2-CB 3.97Å; D187-A191 PolarHBondContact O-N 3.28Å; I188-A191 WeakPolarHBondContact O-CB 3.4Å; I188-A191 PolarHBondContact O-N 3.23Å; A191-K193 PolarHBondContact O-N 3.08Å; A191-W194 WeakPolarHBondContact O-CB 3.19Å; A191-W194 PolarHBondContact O-N 3.49Å; A191-I195 WeakPolarHBondContact O-CD1 3.42Å; A191-I195 WeakPolarHBondContact O-CG1 3.21Å; A191-I195 PolarHBondContact O-N 3.02Å
192M98.9Very high98.4Very high1 Ų119.8 Ų19.81%0.00510%0.098CC..Hα-helixtrans-61.5-43.4175.5-67.6172.380.200111.7I128 I188 I189 E190 W194 I195 K196 L211 L233 M234I128-M192 HydrophobicContact CD1-CB 4.48Å; I128-M192 HydrophobicContact CD1-CG 3.97Å; I188-M192 HydrophobicContact CG2-CG 4.41Å; I188-M192 HydrophobicContact CG2-SD 4.18Å; I188-M192 VanDerWaalsContact O-CG 3.29Å; I188-M192 WeakPolarHBondContact O-CG 3.05Å; I188-M192 PolarHBondContact O-N 3.32Å; I189-M192 WeakPolarHBondContact O-CB 3.34Å; I189-M192 PolarHBondContact O-N 3.05Å; E190-M192 PolarHBondContact O-N 3.13Å; M192-W194 VanDerWaalsContact C-N 3.35Å; M192-W194 PolarHBondContact O-N 3.49Å; M192-I195 PolarHBondContact O-N 2.8Å; M192-K196 WeakPolarHBondContact O-CG 3.38Å; M192-K196 PolarHBondContact O-N 2.76Å; M192-L211 HydrophobicContact CE-CD1 4.36Å; M192-L211 HydrophobicContact CE-CD2 3.99Å; M192-L211 HydrophobicContact SD-CD1 4.32Å; M192-L211 HydrophobicContact SD-CD2 4.15Å; M192-L233 HydrophobicContact CB-CB 4.26Å; M192-L233 HydrophobicContact CB-CD1 4.02Å; M192-L233 HydrophobicContact CE-CB 3.69Å; M192-M234 HydrophobicContact CE-CB 3.96Å; M192-M234 HydrophobicContact CE-CG 4.12Å; M192-M234 HydrophobicContact CE-SD 3.84Å
193K98.8Very high98.4Very high96 Ų9619.9 Ų19.942%0.41710%0.099SC..Hα-helixtrans-61.7-42174.4-71.1170.5-177.5170.20112I189 E190 A191 I195 K196 R197 L233I189-K193 HydrophobicContact CG2-CD 4.4Å; I189-K193 WeakPolarHBondContact O-CG 3.43Å; I189-K193 PolarHBondContact O-N 3.3Å; E190-K193 PolarHBondContact O-N 3.23Å; A191-K193 PolarHBondContact O-N 3.08Å; K193-I195 VanDerWaalsContact C-N 3.32Å; K193-I195 PolarHBondContact O-N 3.4Å; K193-K196 PolarHBondContact O-N 2.8Å; K193-R197 PolarHBondContact O-N 2.95Å; K193-L233 HydrophobicContact CG-CD1 4.04Å; K193-L233 HydrophobicContact CG-CD2 4.2Å
194W98.7Very high98.5Very high0 Ų019.7 Ų19.70%010%0.098CC..Hα-helixtrans-59-45.4173.7-176105.1000110.8L31 I55 L110 E190 A191 M192 R197 E198 F202L31-W194 HydrophobicContact CD1-CH2 4.49Å; L31-W194 HydrophobicContact CD1-CZ2 3.69Å; L31-W194 HydrophobicContact CD2-CZ2 4.46Å; I55-W194 HydrophobicContact CD1-CH2 4.19Å; I55-W194 HydrophobicContact CG2-CH2 4.04Å; I55-W194 HydrophobicContact CG2-CZ2 3.47Å; I55-W194 VanDerWaalsContact CG2-CZ2 3.47Å; L110-W194 HydrophobicContact CD1-CE3 4.06Å; L110-W194 HydrophobicContact CD1-CH2 3.9Å; L110-W194 HydrophobicContact CD1-CZ3 3.63Å; L110-W194 HydrophobicContact CD2-CD2 3.95Å; L110-W194 HydrophobicContact CD2-CE3 3.52Å; L110-W194 HydrophobicContact CD2-CG 4.44Å; L110-W194 HydrophobicContact CD2-CZ3 3.98Å; L110-W194 HydrophobicContact CG-CE3 4.38Å; L110-W194 HydrophobicContact CG-CZ3 4.42Å; E190-W194 WeakPolarHBondContact O-CB 3.42Å; E190-W194 PolarHBondContact O-N 3.12Å; A191-W194 WeakPolarHBondContact O-CB 3.19Å; A191-W194 PolarHBondContact O-N 3.49Å; M192-W194 VanDerWaalsContact C-N 3.35Å; M192-W194 PolarHBondContact O-N 3.49Å; W194-R197 VanDerWaalsContact CD1-NH2 3.26Å; W194-R197 PolarHBondContact O-N 2.81Å; W194-R197 VanDerWaalsContact O-N 3.16Å; W194-E198 HydrophobicContact CD2-CB 4.11Å; W194-E198 HydrophobicContact CD2-CG 3.9Å; W194-E198 HydrophobicContact CE3-CB 4.11Å; W194-E198 HydrophobicContact CE3-CG 4.4Å; W194-E198 HydrophobicContact CG-CG 4.29Å; W194-E198 HydrophobicContact CH2-CB 3.88Å; W194-E198 HydrophobicContact CH2-CG 4.42Å; W194-E198 HydrophobicContact CZ2-CB 3.88Å; W194-E198 HydrophobicContact CZ2-CG 3.92Å; W194-E198 HydrophobicContact CZ3-CB 4Å; W194-E198 WeakPolarHBondContact O-CB 3.46Å; W194-E198 WeakPolarHBondContact O-CG 3.35Å; W194-E198 PolarHBondContact O-N 3.36Å; W194-F202 AromaticContact CH2-CE2 3.71Å; W194-F202 HydrophobicContact CH2-CE2 3.71Å; W194-F202 AromaticContact CH2-CZ 3.93Å; W194-F202 HydrophobicContact CH2-CZ 3.93Å; W194-F202 HydrophobicContact CZ3-CE2 4.37Å
195I98.8Very high98.5Very high0 Ų021 Ų210%011%0.105CC..Hα-helixtrans-63-47.7-179.7-68.9161.6000110.3L110 V126 I128 V160 V162 A191 M192 K193 R197 E198 I199L110-I195 HydrophobicContact CD2-CD1 4.39Å; L110-I195 HydrophobicContact CD2-CG1 4.19Å; V126-I195 HydrophobicContact CG1-CG2 4.13Å; I128-I195 HydrophobicContact CB-CD1 4.37Å; I128-I195 HydrophobicContact CD1-CB 4.3Å; I128-I195 HydrophobicContact CD1-CD1 3.53Å; I128-I195 HydrophobicContact CD1-CG2 4.05Å; I128-I195 HydrophobicContact CG1-CD1 3.7Å; I128-I195 HydrophobicContact CG1-CG2 4.4Å; I128-I195 HydrophobicContact CG2-CD1 3.85Å; V160-I195 HydrophobicContact CB-CD1 4.28Å; V160-I195 HydrophobicContact CG1-CD1 3.74Å; V160-I195 HydrophobicContact CG1-CG1 4.3Å; V162-I195 HydrophobicContact CG2-CD1 4.48Å; A191-I195 WeakPolarHBondContact O-CD1 3.42Å; A191-I195 WeakPolarHBondContact O-CG1 3.21Å; A191-I195 PolarHBondContact O-N 3.02Å; M192-I195 PolarHBondContact O-N 2.8Å; K193-I195 VanDerWaalsContact C-N 3.32Å; K193-I195 PolarHBondContact O-N 3.4Å; I195-R197 PolarHBondContact O-N 2.85Å; I195-R197 VanDerWaalsContact O-N 3.14Å; I195-E198 PolarHBondContact O-N 2.87Å; I195-I199 HydrophobicContact CG2-CB 3.94Å; I195-I199 HydrophobicContact CG2-CD1 4.45Å; I195-I199 HydrophobicContact CG2-CG1 4.16Å; I195-I199 HydrophobicContact CG2-CG2 4.23Å; I195-I199 WeakPolarHBondContact O-CB 3.27Å; I195-I199 WeakPolarHBondContact O-CG2 3.21Å; I195-I199 PolarHBondContact O-N 3.24Å
196K98.5Very high98.5Very high50 Ų5022.2 Ų22.222%0.21711%0.114CC..Hα-helixtrans-56.8-33176.8-68.1-69.3-69.8-159.10112.8M192 K193 S206 V209 N232 L233 E235M192-K196 WeakPolarHBondContact O-CG 3.38Å; M192-K196 PolarHBondContact O-N 2.76Å; K193-K196 PolarHBondContact O-N 2.8Å; K196-S206 WeakPolarHBondContact CD-O 3.49Å; K196-S206 WeakPolarHBondContact CE-O 3.41Å; K196-S206 PolarHBondContact NZ-O 3.41Å; K196-S206 WeakPolarHBondContact O-CB 3.48Å; K196-V209 HydrophobicContact CD-CG2 4.09Å; K196-N232 WeakPolarHBondContact CE-O 3.44Å; K196-N232 PolarHBondContact NZ-O 2.69Å; K196-L233 HydrophobicContact CG-CD2 3.86Å; K196-E235 IonicContact NZ-OE1 2.92Å; K196-E235 PolarHBondContact NZ-OE1 3.06Å
197R97.9Very high98.4Very high98 Ų9825.1 Ų25.137%0.3713%0.134SC..Hα-helixtrans-81.5-40.7-179.4-173.9177.561.8-107.22.4113.4T32 K193 W194 I195T32-R197 HydrophobicContact CG2-CG 4.43Å; K193-R197 PolarHBondContact O-N 2.95Å; W194-R197 VanDerWaalsContact CD1-NH2 3.26Å; W194-R197 PolarHBondContact O-N 2.81Å; W194-R197 VanDerWaalsContact O-N 3.16Å; I195-R197 PolarHBondContact O-N 2.85Å; I195-R197 VanDerWaalsContact O-N 3.14Å
198E98.2Very high98.4Very high6 Ų629.5 Ų29.53%0.02815%0.151CC..Hα-helixtrans-109.6-19.9-165-57.5-58160.200114.5L31 T32 W194 I195 N200 A201L31-E198 WeakPolarHBondContact CA-OE2 3.49Å; L31-E198 WeakPolarHBondContact CB-OE2 3.12Å; L31-E198 HydrophobicContact CD2-CB 4.2Å; T32-E198 WeakPolarHBondContact CB-OE1 3.29Å; T32-E198 WeakPolarHBondContact CG2-OE1 3.38Å; T32-E198 PolarHBondContact N-OE2 3.5Å; T32-E198 PolarHBondContact OG1-OE1 3.25Å; W194-E198 HydrophobicContact CD2-CB 4.11Å; W194-E198 HydrophobicContact CD2-CG 3.9Å; W194-E198 HydrophobicContact CE3-CB 4.11Å; W194-E198 HydrophobicContact CE3-CG 4.4Å; W194-E198 HydrophobicContact CG-CG 4.29Å; W194-E198 HydrophobicContact CH2-CB 3.88Å; W194-E198 HydrophobicContact CH2-CG 4.42Å; W194-E198 HydrophobicContact CZ2-CB 3.88Å; W194-E198 HydrophobicContact CZ2-CG 3.92Å; W194-E198 HydrophobicContact CZ3-CB 4Å; W194-E198 WeakPolarHBondContact O-CB 3.46Å; W194-E198 WeakPolarHBondContact O-CG 3.35Å; W194-E198 PolarHBondContact O-N 3.36Å; I195-E198 PolarHBondContact O-N 2.87Å; E198-N200 PolarHBondContact O-N 2.89Å; E198-N200 VanDerWaalsContact O-N 3.11Å; E198-A201 VanDerWaalsContact O-CB 3.27Å; E198-A201 WeakPolarHBondContact O-CB 3.28Å; E198-A201 PolarHBondContact O-N 3.19Å
199I98.5Very high98.4Very high0 Ų029.5 Ų29.50%015%0.151CC..G310 helixtrans-64.7-25.5-166.1-156.662.3000113.8V112 V126 I158 V160 I195 A201 F202 G204V112-I199 HydrophobicContact CG1-CD1 4.22Å; V112-I199 HydrophobicContact CG2-CD1 4.38Å; V126-I199 HydrophobicContact CG1-CD1 4.42Å; V126-I199 HydrophobicContact CG1-CG1 4Å; V126-I199 HydrophobicContact CG2-CG1 3.69Å; V126-I199 HydrophobicContact CG2-CG2 4.16Å; I158-I199 HydrophobicContact CG2-CD1 4.01Å; I158-I199 HydrophobicContact CG2-CG1 4.47Å; V160-I199 HydrophobicContact CG2-CD1 3.98Å; I195-I199 HydrophobicContact CG2-CB 3.94Å; I195-I199 HydrophobicContact CG2-CD1 4.45Å; I195-I199 HydrophobicContact CG2-CG1 4.16Å; I195-I199 HydrophobicContact CG2-CG2 4.23Å; I195-I199 WeakPolarHBondContact O-CB 3.27Å; I195-I199 WeakPolarHBondContact O-CG2 3.21Å; I195-I199 PolarHBondContact O-N 3.24Å; I199-A201 PolarHBondContact O-N 3.47Å; I199-F202 HydrophobicContact CD1-CB 4.46Å; I199-F202 HydrophobicContact CD1-CD2 4.16Å; I199-F202 WeakPolarHBondContact O-CA 2.99Å; I199-F202 WeakPolarHBondContact O-CB 3.04Å; I199-F202 PolarHBondContact O-N 2.93Å; I199-G204 PolarHBondContact O-N 2.92Å; I199-G204 VanDerWaalsContact O-N 3.09Å
200N98.1Very high98.4Very high85 Ų8529.2 Ų29.246%0.45515%0.149SC..G310 helixtrans-60.5-29174.9-64.35.2000112.1E198 F202 G203 G204 S206E198-N200 PolarHBondContact O-N 2.89Å; E198-N200 VanDerWaalsContact O-N 3.11Å; N200-F202 PolarHBondContact O-N 3.5Å; N200-G203 PolarHBondContact O-N 3.2Å; N200-G204 WeakPolarHBondContact CA-O 3.21Å; N200-G204 PolarHBondContact OD1-O 3.33Å; N200-S206 WeakPolarHBondContact OD1-CB 3.36Å; N200-S206 PolarHBondContact OD1-N 2.9Å; N200-S206 VanDerWaalsContact OD1-N 3.11Å; N200-S206 PolarHBondContact OD1-OG 3.48Å
201A97.2Very high98.4Very high44 Ų4428.7 Ų28.736%0.36415%0.147SC..G310 helixtrans-65.8-18.1175.400000113V29 L31 E198 I199V29-A201 HydrophobicContact CG1-CB 3.72Å; L31-A201 HydrophobicContact CD2-CB 4.21Å; E198-A201 VanDerWaalsContact O-CB 3.27Å; E198-A201 WeakPolarHBondContact O-CB 3.28Å; E198-A201 PolarHBondContact O-N 3.19Å; I199-A201 PolarHBondContact O-N 3.47Å
202F97.8Very high98.4Very high0 Ų028.7 Ų28.70%015%0.147CC..G310 helixtrans-97.92.5176.2-57-96.1000112.5V29 L31 I36 R50 F52 I55 V112 I158 W194 I199 N200V29-F202 HydrophobicContact CB-CE1 4.39Å; V29-F202 HydrophobicContact CG1-CD1 4.42Å; V29-F202 HydrophobicContact CG1-CE1 4.15Å; V29-F202 HydrophobicContact CG1-CE2 4.31Å; V29-F202 HydrophobicContact CG1-CZ 4.1Å; V29-F202 HydrophobicContact CG2-CD1 4.33Å; V29-F202 HydrophobicContact CG2-CE1 4.37Å; L31-F202 HydrophobicContact CD2-CE2 3.53Å; L31-F202 HydrophobicContact CD2-CZ 3.72Å; I36-F202 HydrophobicContact CD1-CE1 3.81Å; I36-F202 HydrophobicContact CD1-CZ 3.64Å; R50-F202 PolarHBondContact NH2-O 3.1Å; F52-F202 HydrophobicContact CB-CE1 4.37Å; F52-F202 HydrophobicContact CD1-CE1 4.29Å; F52-F202 AromaticContact CD2-CD1 3.78Å; F52-F202 HydrophobicContact CD2-CD1 3.78Å; F52-F202 AromaticContact CD2-CE1 3.58Å; F52-F202 HydrophobicContact CD2-CE1 3.58Å; F52-F202 AromaticContact CE2-CD1 3.8Å; F52-F202 HydrophobicContact CE2-CD1 3.8Å; F52-F202 AromaticContact CE2-CE1 3.88Å; F52-F202 HydrophobicContact CE2-CE1 3.88Å; F52-F202 HydrophobicContact CG-CD1 4.48Å; F52-F202 AromaticContact CG-CE1 3.83Å; F52-F202 HydrophobicContact CG-CE1 3.83Å; F52-F202 HydrophobicContact CZ-CE1 4.36Å; I55-F202 HydrophobicContact CD1-CE1 4.19Å; I55-F202 HydrophobicContact CD1-CZ 3.93Å; V112-F202 HydrophobicContact CB-CD1 4.17Å; V112-F202 HydrophobicContact CB-CE1 4.17Å; V112-F202 HydrophobicContact CG1-CB 4.16Å; V112-F202 HydrophobicContact CG1-CD1 3.68Å; V112-F202 HydrophobicContact CG1-CE1 4.18Å; V112-F202 HydrophobicContact CG1-CG 3.91Å; V112-F202 HydrophobicContact CG2-CE1 4.32Å; V112-F202 HydrophobicContact CG2-CZ 4.36Å; I158-F202 HydrophobicContact CD1-CB 4.14Å; I158-F202 WeakPolarHBondContact CD1-O 3.43Å; W194-F202 AromaticContact CH2-CE2 3.71Å; W194-F202 HydrophobicContact CH2-CE2 3.71Å; W194-F202 AromaticContact CH2-CZ 3.93Å; W194-F202 HydrophobicContact CH2-CZ 3.93Å; W194-F202 HydrophobicContact CZ3-CE2 4.37Å; I199-F202 HydrophobicContact CD1-CB 4.46Å; I199-F202 HydrophobicContact CD1-CD2 4.16Å; I199-F202 WeakPolarHBondContact O-CA 2.99Å; I199-F202 WeakPolarHBondContact O-CB 3.04Å; I199-F202 PolarHBondContact O-N 2.93Å; N200-F202 PolarHBondContact O-N 3.5Å
203G98.1Very high98.4Very high3 Ų328.7 Ų28.73%0.03115%0.147CC..THydrogen-bonded Turntrans79.522.7-171.900000113.2P123 C124 N200P123-G203 CarbonylContact C-O 3.55Å; P123-G203 VanDerWaalsContact CA-O 3.3Å; P123-G203 WeakPolarHBondContact CA-O 3.34Å; C124-G203 PolarHBondContact N-O 3.27Å; N200-G203 PolarHBondContact O-N 3.2Å
204G98.6Very high98.3Very high1 Ų124.4 Ų24.41%0.0113%0.128CC..EExtended strand (participates in β ladder)trans-89.2155.2173.400000112.2C124 I158 I199 N200C124-G204 CarbonylContact O-C 3.6Å; C124-G204 WeakPolarHBondContact O-CA 3.31Å; I158-G204 VanDerWaalsContact CD1-CA 3.42Å; I158-G204 VanDerWaalsContact CD1-N 3.29Å; I199-G204 PolarHBondContact O-N 2.92Å; I199-G204 VanDerWaalsContact O-N 3.09Å; N200-G204 WeakPolarHBondContact CA-O 3.21Å; N200-G204 PolarHBondContact OD1-O 3.33Å
205D98.5Very high98.1Very high27 Ų2725.6 Ų25.614%0.14414%0.137CC..EExtended strand (participates in β ladder)trans-97.4102.6172.6-174-12.6000109.2P123 C124 S207 R208P123-D205 HydrophobicContact CB-CB 3.96Å; P123-D205 HydrophobicContact CG-CB 4.37Å; C124-D205 WeakPolarHBondContact O-CB 3.48Å; C124-D205 PolarHBondContact O-N 3.07Å; D205-S207 PolarHBondContact O-N 3.49Å; D205-S207 VanDerWaalsContact O-N 3.08Å; D205-S207 WeakPolarHBondContact OD1-CA 3.24Å; D205-S207 WeakPolarHBondContact OD1-CB 3.42Å; D205-S207 PolarHBondContact OD1-N 3.22Å; D205-S207 PolarHBondContact OD1-OG 2.97Å; D205-R208 HydrophobicContact CB-CB 4.21Å; D205-R208 PolarHBondContact O-N 2.76Å; D205-R208 WeakPolarHBondContact OD2-CG 3.34Å; D205-R208 IonicContact OD2-CZ 3.98Å; D205-R208 IonicContact OD2-NE 3.78Å; D205-R208 PolarHBondContact OD2-NE 2.91Å; D205-R208 IonicContact OD2-NH2 3.71Å
206S98Very high98Very high27 Ų2726 Ų2619%0.18914%0.139CC..EExtended strand (participates in β ladder)trans-63.2-12.2178.2670000113.8K196 N200K196-S206 WeakPolarHBondContact CD-O 3.49Å; K196-S206 WeakPolarHBondContact CE-O 3.41Å; K196-S206 PolarHBondContact NZ-O 3.41Å; K196-S206 WeakPolarHBondContact O-CB 3.48Å; N200-S206 WeakPolarHBondContact OD1-CB 3.36Å; N200-S206 PolarHBondContact OD1-N 2.9Å; N200-S206 VanDerWaalsContact OD1-N 3.11Å; N200-S206 PolarHBondContact OD1-OG 3.48Å
207S97.9Very high97.9Very high72 Ų7223.6 Ų23.650%0.50313%0.129SC..EExtended strand (participates in β ladder)trans-91.7-3.2173.675.90000114.1D205 E235D205-S207 PolarHBondContact O-N 3.49Å; D205-S207 VanDerWaalsContact O-N 3.08Å; D205-S207 WeakPolarHBondContact OD1-CA 3.24Å; D205-S207 WeakPolarHBondContact OD1-CB 3.42Å; D205-S207 PolarHBondContact OD1-N 3.22Å; D205-S207 PolarHBondContact OD1-OG 2.97Å; S207-E235 WeakPolarHBondContact O-CG 3.3Å
208R98.5Very high97.9Very high91 Ų9118.9 Ų18.934%0.34311%0.111SC..EExtended strand (participates in β ladder)trans-126.468.1177.6-66.2-167.1-64.3155.8-0.1110.9P123 P125 V126 D205P123-R208 PolarHBondContact O-NH2 2.98Å; P125-R208 HydrophobicContact CB-CB 4.17Å; V126-R208 PolarHBondContact N-O 3.23Å; D205-R208 HydrophobicContact CB-CB 4.21Å; D205-R208 PolarHBondContact O-N 2.76Å; D205-R208 WeakPolarHBondContact OD2-CG 3.34Å; D205-R208 IonicContact OD2-CZ 3.98Å; D205-R208 IonicContact OD2-NE 3.78Å; D205-R208 PolarHBondContact OD2-NE 2.91Å; D205-R208 IonicContact OD2-NH2 3.71Å
209V98.8Very high97.9Very high1 Ų119 Ų191%0.00611%0.112CC..EExtended strand (participates in β ladder)trans-104.5123.2-177.9178.10000110.4V126 I128 K196 M234 E235V126-V209 HydrophobicContact CB-CG2 4.34Å; V126-V209 WeakPolarHBondContact O-CA 3.24Å; I128-V209 HydrophobicContact CD1-CG1 3.4Å; I128-V209 VanDerWaalsContact CD1-CG1 3.4Å; I128-V209 HydrophobicContact CG1-CG1 3.82Å; K196-V209 HydrophobicContact CD-CG2 4.09Å; V209-M234 HydrophobicContact CG1-CB 4.43Å; V209-E235 PolarHBondContact O-N 3.47Å
210T98.9Very high97.9Very high0 Ų019 Ų190%011%0.112CC..EExtended strand (participates in β ladder)trans-105.9122.1173.1-55.40000109.6V126 V127 I128 Q236 I238 V521V126-T210 PolarHBondContact O-N 3.32Å; V127-T210 CarbonylContact C-O 3.53Å; V127-T210 WeakPolarHBondContact CA-O 3.38Å; I128-T210 PolarHBondContact N-O 3.05Å; T210-Q236 WeakPolarHBondContact CA-O 3.32Å; T210-Q236 HydrophobicContact CG2-CG 3.99Å; T210-Q236 VanDerWaalsContact OG1-CG 3.27Å; T210-Q236 WeakPolarHBondContact OG1-CG 3.1Å; T210-Q236 PolarHBondContact OG1-NE2 3.14Å; T210-I238 HydrophobicContact CG2-CD1 3.8Å; T210-I238 HydrophobicContact CG2-CG1 3.8Å; T210-V521 HydrophobicContact CG2-CG2 4.23Å
211L98.9Very high98Very high0 Ų014.9 Ų14.90%09%0.091CC..EExtended strand (participates in β ladder)trans-89.4119.7171.5-171.465.3000109.2I128 I130 M192 V221 L224 M234 Q236 A237 I238I128-L211 HydrophobicContact CB-CD1 3.78Å; I128-L211 HydrophobicContact CG2-CD1 3.89Å; I130-L211 HydrophobicContact CD1-CD1 4.11Å; I130-L211 HydrophobicContact CG1-CD1 3.81Å; M192-L211 HydrophobicContact CE-CD1 4.36Å; M192-L211 HydrophobicContact CE-CD2 3.99Å; M192-L211 HydrophobicContact SD-CD1 4.32Å; M192-L211 HydrophobicContact SD-CD2 4.15Å; L211-V221 HydrophobicContact CB-CG1 4.26Å; L211-V221 HydrophobicContact CD1-CG2 4.36Å; L211-V221 HydrophobicContact CD2-CB 4.18Å; L211-V221 HydrophobicContact CD2-CG1 3.96Å; L211-V221 HydrophobicContact CD2-CG2 3.85Å; L211-V221 HydrophobicContact CG-CB 4.28Å; L211-V221 HydrophobicContact CG-CG1 3.92Å; L211-V221 HydrophobicContact CG-CG2 3.61Å; L211-L224 HydrophobicContact CD2-CB 4.08Å; L211-L224 HydrophobicContact CD2-CD1 3.94Å; L211-M234 HydrophobicContact CB-CB 4.22Å; L211-M234 HydrophobicContact CB-CG 4.48Å; L211-M234 HydrophobicContact CB-SD 3.44Å; L211-M234 WeakPolarHBondContact CB-SD 3.37Å; L211-M234 HydrophobicContact CD2-CE 4.47Å; L211-M234 HydrophobicContact CD2-SD 3.45Å; L211-M234 WeakPolarHBondContact CD2-SD 3.33Å; L211-M234 HydrophobicContact CG-SD 4.07Å; L211-Q236 PolarHBondContact N-O 2.88Å; L211-Q236 VanDerWaalsContact N-O 3.07Å; L211-A237 CarbonylContact O-C 3.6Å; L211-A237 WeakPolarHBondContact O-CA 3.42Å; L211-I238 PolarHBondContact O-N 3.34Å
212M98.9Very high98Very high1 Ų112.8 Ų12.81%0.0057%0.073CC..EExtended strand (participates in β ladder)trans-119.9136.2-175.8-178.5175.5-177.400110V127 I128 F129 I130 F159 I238 M240 L517V127-M212 HydrophobicContact CG1-CB 3.7Å; V127-M212 HydrophobicContact CG1-CG 4.46Å; V127-M212 HydrophobicContact CG1-SD 3.93Å; I128-M212 PolarHBondContact O-N 3.48Å; I128-M212 VanDerWaalsContact O-O 3.09Å; F129-M212 CarbonylContact C-O 3.57Å; F129-M212 VanDerWaalsContact CA-O 3.31Å; F129-M212 WeakPolarHBondContact CA-O 3.47Å; F129-M212 HydrophobicContact CD2-CB 4.22Å; F129-M212 HydrophobicContact CD2-CE 4.44Å; F129-M212 HydrophobicContact CD2-CG 3.76Å; F129-M212 HydrophobicContact CD2-SD 4Å; F129-M212 HydrophobicContact CE2-CE 4.35Å; F129-M212 HydrophobicContact CE2-CG 4.15Å; F129-M212 HydrophobicContact CE2-SD 4.47Å; I130-M212 PolarHBondContact N-O 3.08Å; F159-M212 HydrophobicContact CE2-SD 4.39Å; M212-I238 CarbonylContact C-O 3.41Å; M212-I238 VanDerWaalsContact CA-O 3.3Å; M212-I238 WeakPolarHBondContact CA-O 3.29Å; M212-I238 HydrophobicContact CB-CB 4.06Å; M212-I238 HydrophobicContact CE-CG2 4.2Å; M212-I238 HydrophobicContact CG-CB 3.82Å; M212-I238 HydrophobicContact CG-CD1 4.44Å; M212-I238 HydrophobicContact CG-CG2 3.86Å; M212-I238 HydrophobicContact SD-CD1 4.2Å; M212-I238 HydrophobicContact SD-CG2 4.39Å; M212-M240 HydrophobicContact CE-SD 3.28Å; M212-M240 WeakPolarHBondContact CE-SD 3.49Å; M212-L517 HydrophobicContact CE-CD1 4.1Å; M212-L517 HydrophobicContact CE-CD2 4.49Å
213G98.6Very high98Very high0 Ų012.8 Ų12.80%07%0.073CC..EExtended strand (participates in β ladder)trans-152.5154.8178.600000113.6I130 G218 I238 M240I130-G213 WeakPolarHBondContact O-CA 3.47Å; G213-G218 VanDerWaalsContact C-CA 3.46Å; G213-G218 WeakPolarHBondContact O-CA 3.25Å; G213-I238 PolarHBondContact N-O 3.43Å; G213-M240 PolarHBondContact O-N 2.03Å
214H97Very high98.1Very high6 Ų612.7 Ų12.73%0.0287%0.072CC..EExtended strand (participates in β ladder)trans-126.6141.7179.1165.6-85.4000112.5F129 I130 G132 S216 G217 G218 M240 H487 S488 D490 L491F129-H214 HydrophobicContact CZ-CB 4.27Å; I130-H214 PolarHBondContact O-N 2.56Å; G132-H214 WeakPolarHBondContact CA-O 3.09Å; G132-H214 PolarHBondContact N-O 3.3Å; H214-S216 PolarHBondContact O-N 3.09Å; H214-G217 VanDerWaalsContact O-CA 3.32Å; H214-G217 WeakPolarHBondContact O-CA 3.32Å; H214-G217 PolarHBondContact O-N 2.92Å; H214-G218 VanDerWaalsContact N-N 3.19Å; H214-G218 PolarHBondContact O-N 3.05Å; H214-M240 CarbonylContact C-O 3.5Å; H214-M240 VanDerWaalsContact CA-O 3.23Å; H214-M240 WeakPolarHBondContact CA-O 3.34Å; H214-M240 HydrophobicContact CB-CB 4.13Å; H214-H487 AromaticContact CE1-CE1 3.77Å; H214-H487 AromaticContact CE1-NE2 3.43Å; H214-H487 PolarHBondContact CE1-NE2 2.78Å; H214-H487 AromaticContact NE2-CE1 3.58Å; H214-H487 AromaticContact NE2-NE2 3.69Å; H214-S488 VanDerWaalsContact CE1-CB 3.49Å; H214-S488 WeakPolarHBondContact CE1-CB 3.43Å; H214-S488 PolarHBondContact CE1-OG 2.65Å; H214-S488 VanDerWaalsContact NE2-CA 3.29Å; H214-S488 WeakPolarHBondContact NE2-CA 3.3Å; H214-S488 WeakPolarHBondContact NE2-CB 3.41Å; H214-S488 PolarHBondContact NE2-OG 3.02Å; H214-D490 IonicContact CD2-OD1 2.65Å; H214-D490 IonicContact NE2-OD1 3.07Å; H214-L491 HydrophobicContact CB-CD1 3.73Å; H214-L491 HydrophobicContact CB-CD2 4.02Å; H214-L491 HydrophobicContact CB-CG 4.1Å; H214-L491 WeakPolarHBondContact ND1-CD1 3.47Å
215S95.1Very high98Very high25 Ų2512.6 Ų12.618%0.1757%0.071CC..THydrogen-bonded Turntrans59.6-128.7179.5-1660000111.7G217 G218 S219 M240 S241 H487S215-G217 PolarHBondContact O-N 2.79Å; S215-G218 CarbonylContact O-C 3.49Å; S215-G218 WeakPolarHBondContact O-CA 3.13Å; S215-G218 PolarHBondContact O-N 2.96Å; S215-S219 PolarHBondContact O-N 3.39Å; S215-M240 PolarHBondContact N-O 3.39Å; S215-S241 WeakPolarHBondContact CA-O 3.46Å; S215-H487 WeakPolarHBondContact CB-NE2 3.37Å; S215-H487 PolarHBondContact OG-NE2 3.36Å
216S95.3Very high97.9Very high8 Ų811.9 Ų11.96%0.0567%0.067CC..Hα-helixtrans-54.9-32.3169.456.90000112.9G132 G133 E134 F135 H214 G218 S219 A220G132-S216 VanDerWaalsContact C-OG 3.24Å; G132-S216 WeakPolarHBondContact CA-OG 3.39Å; G133-S216 PolarHBondContact N-OG 2.93Å; G133-S216 VanDerWaalsContact N-OG 3.14Å; E134-S216 PolarHBondContact N-OG 3.08Å; F135-S216 WeakPolarHBondContact CE1-O 3.31Å; F135-S216 WeakPolarHBondContact CZ-O 3.12Å; F135-S216 PolarHBondContact N-OG 3.32Å; H214-S216 PolarHBondContact O-N 3.09Å; S216-G218 VanDerWaalsContact C-N 3.34Å; S216-S219 PolarHBondContact O-N 3.1Å; S216-A220 WeakPolarHBondContact O-CB 3.41Å; S216-A220 PolarHBondContact O-N 3.06Å
217G97.9Very high97.9Very high0 Ų010.6 Ų10.60%06%0.058CC..Hα-helixtrans-65.9-37.4171.400000111.9H131 H214 S215 A220 V221H131-G217 VanDerWaalsContact O-CA 3.23Å; H131-G217 WeakPolarHBondContact O-CA 3.37Å; H131-G217 PolarHBondContact O-N 3.35Å; H214-G217 VanDerWaalsContact O-CA 3.32Å; H214-G217 WeakPolarHBondContact O-CA 3.32Å; H214-G217 PolarHBondContact O-N 2.92Å; S215-G217 PolarHBondContact O-N 2.79Å; G217-A220 WeakPolarHBondContact O-CB 3.49Å; G217-A220 PolarHBondContact O-N 2.97Å; G217-V221 VanDerWaalsContact O-CG2 3.32Å; G217-V221 WeakPolarHBondContact O-CG2 3.48Å; G217-V221 PolarHBondContact O-N 2.86Å
218G98.2Very high97.7Very high0 Ų010 Ų100%05%0.053CC..Hα-helixtrans-66.6-42.1172.700000112G213 H214 S215 S216 A220 V221 S222 V239G213-G218 VanDerWaalsContact C-CA 3.46Å; G213-G218 WeakPolarHBondContact O-CA 3.25Å; H214-G218 VanDerWaalsContact N-N 3.19Å; H214-G218 PolarHBondContact O-N 3.05Å; S215-G218 CarbonylContact O-C 3.49Å; S215-G218 WeakPolarHBondContact O-CA 3.13Å; S215-G218 PolarHBondContact O-N 2.96Å; S216-G218 VanDerWaalsContact C-N 3.34Å; G218-A220 VanDerWaalsContact C-N 3.31Å; G218-A220 PolarHBondContact O-N 3.48Å; G218-V221 PolarHBondContact O-N 2.8Å; G218-S222 WeakPolarHBondContact O-CB 3.26Å; G218-S222 PolarHBondContact O-N 2.88Å; G218-V239 WeakPolarHBondContact O-CG1 3.48Å
219S97.7Very high97.6Very high7 Ų710.3 Ų10.35%0.0496%0.056CC..Hα-helixtrans-60.1-40.4169.8-71.10000111.9S215 S216 S222 L223 S243S215-S219 PolarHBondContact O-N 3.39Å; S216-S219 PolarHBondContact O-N 3.1Å; S219-S222 PolarHBondContact O-N 3.34Å; S219-L223 WeakPolarHBondContact O-CB 3.36Å; S219-L223 VanDerWaalsContact O-CG 3.24Å; S219-L223 WeakPolarHBondContact O-CG 3.24Å; S219-L223 PolarHBondContact O-N 2.79Å; S219-S243 WeakPolarHBondContact CB-O 3.41Å; S219-S243 PolarHBondContact OG-N 3.3Å; S219-S243 VanDerWaalsContact OG-N 3.1Å; S219-S243 PolarHBondContact OG-O 2.96Å
220A98.5Very high97.6Very high0 Ų010.2 Ų10.20%06%0.056CC..Hα-helixtrans-61.3-47.3174.800000111.2I130 F135 L185 I188 S216 G217 G218 S222 L223 L224I130-A220 HydrophobicContact CG2-CB 4.37Å; F135-A220 HydrophobicContact CE1-CB 3.92Å; F135-A220 HydrophobicContact CZ-CB 4.3Å; L185-A220 HydrophobicContact CD2-CB 3.96Å; I188-A220 HydrophobicContact CD1-CB 4.29Å; S216-A220 WeakPolarHBondContact O-CB 3.41Å; S216-A220 PolarHBondContact O-N 3.06Å; G217-A220 WeakPolarHBondContact O-CB 3.49Å; G217-A220 PolarHBondContact O-N 2.97Å; G218-A220 VanDerWaalsContact C-N 3.31Å; G218-A220 PolarHBondContact O-N 3.48Å; A220-S222 PolarHBondContact O-N 2.87Å; A220-L223 PolarHBondContact O-N 2.89Å; A220-L224 VanDerWaalsContact O-CB 3.31Å; A220-L224 WeakPolarHBondContact O-CB 3.35Å; A220-L224 WeakPolarHBondContact O-CG 3.23Å; A220-L224 PolarHBondContact O-N 3.32Å
221V98.8Very high97.3Very high0 Ų015.1 Ų15.10%08%0.079CC..Hα-helixtrans-59.4-48.2176.1172.50000111.2I130 L211 G217 G218 L223 L224 T225 A237 V239I130-V221 HydrophobicContact CB-CG2 4.3Å; I130-V221 HydrophobicContact CG1-CG2 4.06Å; L211-V221 HydrophobicContact CB-CG1 4.26Å; L211-V221 HydrophobicContact CD1-CG2 4.36Å; L211-V221 HydrophobicContact CD2-CB 4.18Å; L211-V221 HydrophobicContact CD2-CG1 3.96Å; L211-V221 HydrophobicContact CD2-CG2 3.85Å; L211-V221 HydrophobicContact CG-CB 4.28Å; L211-V221 HydrophobicContact CG-CG1 3.92Å; L211-V221 HydrophobicContact CG-CG2 3.61Å; G217-V221 VanDerWaalsContact O-CG2 3.32Å; G217-V221 WeakPolarHBondContact O-CG2 3.48Å; G217-V221 PolarHBondContact O-N 2.86Å; G218-V221 PolarHBondContact O-N 2.8Å; V221-L223 PolarHBondContact O-N 3.05Å; V221-L224 PolarHBondContact O-N 3.28Å; V221-L224 VanDerWaalsContact O-N 3.16Å; V221-T225 WeakPolarHBondContact O-CG2 3.3Å; V221-T225 PolarHBondContact O-N 3.17Å; V221-A237 HydrophobicContact CG1-CB 3.79Å; V221-V239 HydrophobicContact CB-CG2 4.11Å; V221-V239 HydrophobicContact CG1-CG2 3.64Å
222S98.5Very high97.2Very high0 Ų021 Ų210%011%0.11CC..Hα-helixtrans-57.5-46.6176.9179.70000111.3G218 S219 A220 L224 T225 A244 Y365 D459G218-S222 WeakPolarHBondContact O-CB 3.26Å; G218-S222 PolarHBondContact O-N 2.88Å; S219-S222 PolarHBondContact O-N 3.34Å; A220-S222 PolarHBondContact O-N 2.87Å; S222-L224 PolarHBondContact O-N 3.07Å; S222-T225 PolarHBondContact O-N 2.9Å; S222-T225 PolarHBondContact O-OG1 3.05Å; S222-A244 VanDerWaalsContact CB-N 3.3Å; S222-A244 VanDerWaalsContact OG-CB 3.23Å; S222-A244 WeakPolarHBondContact OG-CB 3.48Å; S222-A244 PolarHBondContact OG-N 3.46Å; S222-Y365 PolarHBondContact OG-OH 3.48Å; S222-D459 WeakPolarHBondContact CB-OD2 3.47Å; S222-D459 PolarHBondContact OG-OD2 2.86Å
223L98.1Very high97.1Very high0 Ų021.9 Ų21.90%012%0.115CC..Hα-helixtrans-61.6-42.1174.9-74.3168.3000112.4S219 A220 V221 T225 L226 S227 A244 A249 P340 L349 P353S219-L223 WeakPolarHBondContact O-CB 3.36Å; S219-L223 VanDerWaalsContact O-CG 3.24Å; S219-L223 WeakPolarHBondContact O-CG 3.24Å; S219-L223 PolarHBondContact O-N 2.79Å; A220-L223 PolarHBondContact O-N 2.89Å; V221-L223 PolarHBondContact O-N 3.05Å; L223-T225 PolarHBondContact O-N 3.35Å; L223-L226 WeakPolarHBondContact O-CB 3.46Å; L223-L226 PolarHBondContact O-N 3.38Å; L223-S227 PolarHBondContact O-N 2.95Å; L223-A244 HydrophobicContact CD2-CB 3.57Å; L223-A244 HydrophobicContact CG-CB 3.76Å; L223-A249 WeakPolarHBondContact CD1-O 3.49Å; L223-P340 HydrophobicContact CD1-CB 3.94Å; L223-P340 HydrophobicContact CD1-CG 3.78Å; L223-L349 HydrophobicContact CB-CD2 4.23Å; L223-L349 HydrophobicContact CD1-CD1 4.34Å; L223-L349 HydrophobicContact CD2-CD1 3.91Å; L223-L349 HydrophobicContact CD2-CD2 4.01Å; L223-P353 HydrophobicContact CD2-CB 4.22Å; L223-P353 HydrophobicContact CD2-CG 3.7Å
224L98.6Very high97.1Very high0 Ų022 Ų220%012%0.116CC..Hα-helixtrans-67.4-25178.5-72.9172.3000112I188 I189 L211 A220 V221 S222 L226 S227 T230 I348I188-L224 HydrophobicContact CB-CD1 4.2Å; I188-L224 HydrophobicContact CD1-CD1 4.5Å; I188-L224 HydrophobicContact CG2-CD1 3.51Å; I189-L224 HydrophobicContact CD1-CD2 3.79Å; I189-L224 HydrophobicContact CG1-CD2 3.67Å; L211-L224 HydrophobicContact CD2-CB 4.08Å; L211-L224 HydrophobicContact CD2-CD1 3.94Å; A220-L224 VanDerWaalsContact O-CB 3.31Å; A220-L224 WeakPolarHBondContact O-CB 3.35Å; A220-L224 WeakPolarHBondContact O-CG 3.23Å; A220-L224 PolarHBondContact O-N 3.32Å; V221-L224 PolarHBondContact O-N 3.28Å; V221-L224 VanDerWaalsContact O-N 3.16Å; S222-L224 PolarHBondContact O-N 3.07Å; L224-L226 PolarHBondContact O-N 3.21Å; L224-S227 PolarHBondContact O-N 3.43Å; L224-T230 HydrophobicContact CB-CG2 4.09Å; L224-T230 HydrophobicContact CD2-CG2 3.75Å; L224-T230 HydrophobicContact CG-CG2 4.47Å; L224-T230 WeakPolarHBondContact O-CB 3.29Å; L224-T230 PolarHBondContact O-OG1 3.2Å; L224-I348 HydrophobicContact CD2-CG2 4.33Å
225T98.1Very high97.2Very high0 Ų025.4 Ų25.40%013%0.132CC..Hα-helixtrans-66.8-24.4170.575.70000113.2V221 S222 L223 M234 A237 R360 R361 M363 Y365V221-T225 WeakPolarHBondContact O-CG2 3.3Å; V221-T225 PolarHBondContact O-N 3.17Å; S222-T225 PolarHBondContact O-N 2.9Å; S222-T225 PolarHBondContact O-OG1 3.05Å; L223-T225 PolarHBondContact O-N 3.35Å; T225-M234 VanDerWaalsContact CA-CE 3.43Å; T225-M234 HydrophobicContact CG2-CE 3.67Å; T225-A237 HydrophobicContact CG2-CB 4Å; T225-R360 PolarHBondContact OG1-NH2 2.64Å; T225-R361 PolarHBondContact O-NH2 3.43Å; T225-M363 HydrophobicContact CG2-CE 4.49Å; T225-M363 HydrophobicContact CG2-SD 4.08Å; T225-Y365 HydrophobicContact CG2-CE2 3.91Å
226L96.1Very high97.3Very high12 Ų1224.7 Ų24.76%0.06313%0.125CC..Hα-helixtrans-89.2-15.7179-54.9176.2000112.7L223 L224 A244 P353 L356 M357 R360L223-L226 WeakPolarHBondContact O-CB 3.46Å; L223-L226 PolarHBondContact O-N 3.38Å; L224-L226 PolarHBondContact O-N 3.21Å; L226-A244 HydrophobicContact CD1-CB 4.06Å; L226-P353 HydrophobicContact CD1-CB 3.83Å; L226-L356 HydrophobicContact CB-CB 4.05Å; L226-L356 HydrophobicContact CB-CD1 4.06Å; L226-L356 HydrophobicContact CD1-CB 4.27Å; L226-L356 HydrophobicContact CD2-CB 4.42Å; L226-L356 HydrophobicContact CG-CB 4.48Å; L226-M357 HydrophobicContact CD1-CE 3.98Å; L226-M357 HydrophobicContact CD1-CG 3.99Å; L226-M357 HydrophobicContact CD2-CG 3.7Å; L226-R360 HydrophobicContact CD2-CB 3.72Å
227S96.7Very high97.5Very high0 Ų024.3 Ų24.30%012%0.123CC..  trans-77135.6-175.5-171.50000111.5L223 L224 K229 T230 I348 R361L223-S227 PolarHBondContact O-N 2.95Å; L224-S227 PolarHBondContact O-N 3.43Å; S227-K229 PolarHBondContact O-N 3.06Å; S227-K229 WeakPolarHBondContact OG-CB 3.32Å; S227-K229 PolarHBondContact OG-N 2.87Å; S227-T230 PolarHBondContact O-N 3.18Å; S227-T230 PolarHBondContact O-OG1 3.33Å; S227-I348 VanDerWaalsContact CB-O 3.23Å; S227-I348 WeakPolarHBondContact CB-O 3.33Å; S227-I348 PolarHBondContact OG-O 2.81Å; S227-R361 PolarHBondContact O-NH2 2.92Å
228P94.4Very high97.6Very high59 Ų5924.3 Ų24.338%0.38312%0.123SC..G310 helixtrans-68.5-22.6168.127.8-33.8000111.9T230 E231 P350P228-T230 PolarHBondContact O-N 2.99Å; P228-T230 VanDerWaalsContact O-N 3.16Å; P228-E231 WeakPolarHBondContact O-CG 3.44Å; P228-E231 PolarHBondContact O-N 3.41Å; P228-P350 HydrophobicContact CG-CG 4.43Å
229K96.8Very high97.6Very high97 Ų9724.3 Ų24.342%0.42212%0.123SC..G310 helixtrans-69.9-9.8-179.7-59.1-70.2-175.5174.80113.5I189 S227 D346 G347 I348I189-K229 HydrophobicContact CD1-CB 3.95Å; S227-K229 PolarHBondContact O-N 3.06Å; S227-K229 WeakPolarHBondContact OG-CB 3.32Å; S227-K229 PolarHBondContact OG-N 2.87Å; K229-D346 WeakPolarHBondContact CE-O 3.37Å; K229-D346 PolarHBondContact NZ-O 2.89Å; K229-G347 WeakPolarHBondContact CE-O 3.43Å; K229-I348 HydrophobicContact CG-CG1 4.35Å
230T97.9Very high97.6Very high0 Ų024 Ų240%012%0.12CC..G310 helixtrans-110.36.9-178.363.70000113.5I189 L224 S227 P228 N232 L233 R361I189-T230 HydrophobicContact CD1-CG2 4.27Å; I189-T230 HydrophobicContact CG1-CG2 4Å; L224-T230 HydrophobicContact CB-CG2 4.09Å; L224-T230 HydrophobicContact CD2-CG2 3.75Å; L224-T230 HydrophobicContact CG-CG2 4.47Å; L224-T230 WeakPolarHBondContact O-CB 3.29Å; L224-T230 PolarHBondContact O-OG1 3.2Å; S227-T230 PolarHBondContact O-N 3.18Å; S227-T230 PolarHBondContact O-OG1 3.33Å; P228-T230 PolarHBondContact O-N 2.99Å; P228-T230 VanDerWaalsContact O-N 3.16Å; T230-N232 PolarHBondContact O-N 3.44Å; T230-L233 WeakPolarHBondContact O-CB 3.45Å; T230-L233 PolarHBondContact O-N 3.25Å; T230-R361 PolarHBondContact OG1-NH2 2.67Å
231E93.7Very high97.5Very high102 Ų10224 Ų2448%0.47712%0.12SC..THydrogen-bonded Turntrans-54.8130.9173-74.6180-170.100110.7P228 L233P228-E231 WeakPolarHBondContact O-CG 3.44Å; P228-E231 PolarHBondContact O-N 3.41Å; E231-L233 PolarHBondContact O-N 2.91Å
232N95.8Very high97.3Very high124 Ų12424 Ų2466%0.66312%0.12SC*.THydrogen-bonded Turntrans62.513-177.6-46.5-64.5000115.3K196 T230K196-N232 WeakPolarHBondContact CE-O 3.44Å; K196-N232 PolarHBondContact NZ-O 2.69Å; T230-N232 PolarHBondContact O-N 3.44Å
233L98.5Very high97.1Very high20 Ų2024 Ų2411%0.10512%0.12CC..THydrogen-bonded Turntrans-95.5-15174.6-59.5-172.1000113.6I189 M192 K193 K196 T230 E231I189-L233 HydrophobicContact CG2-CD1 4.16Å; M192-L233 HydrophobicContact CB-CB 4.26Å; M192-L233 HydrophobicContact CB-CD1 4.02Å; M192-L233 HydrophobicContact CE-CB 3.69Å; K193-L233 HydrophobicContact CG-CD1 4.04Å; K193-L233 HydrophobicContact CG-CD2 4.2Å; K196-L233 HydrophobicContact CG-CD2 3.86Å; T230-L233 WeakPolarHBondContact O-CB 3.45Å; T230-L233 PolarHBondContact O-N 3.25Å; E231-L233 PolarHBondContact O-N 2.91Å
234M98Very high96.9Very high2 Ų224 Ų241%0.0112%0.12CC..  trans-154.6146176.765.5-169.2178.800110.1M192 V209 L211 T225 M363M192-M234 HydrophobicContact CE-CB 3.96Å; M192-M234 HydrophobicContact CE-CG 4.12Å; M192-M234 HydrophobicContact CE-SD 3.84Å; V209-M234 HydrophobicContact CG1-CB 4.43Å; L211-M234 HydrophobicContact CB-CB 4.22Å; L211-M234 HydrophobicContact CB-CG 4.48Å; L211-M234 HydrophobicContact CB-SD 3.44Å; L211-M234 WeakPolarHBondContact CB-SD 3.37Å; L211-M234 HydrophobicContact CD2-CE 4.47Å; L211-M234 HydrophobicContact CD2-SD 3.45Å; L211-M234 WeakPolarHBondContact CD2-SD 3.33Å; L211-M234 HydrophobicContact CG-SD 4.07Å; T225-M234 VanDerWaalsContact CA-CE 3.43Å; T225-M234 HydrophobicContact CG2-CE 3.67Å; M234-M363 HydrophobicContact CE-CE 4.24Å; M234-M363 HydrophobicContact CE-SD 4.39Å
235E98Very high96.5Very high77 Ų7724.3 Ų24.336%0.3612%0.122SC..SBendtrans-105.4-17.5-176.8-44.9-37.1149.600112.9K196 S207 V209 P364K196-E235 IonicContact NZ-OE1 2.92Å; K196-E235 PolarHBondContact NZ-OE1 3.06Å; S207-E235 WeakPolarHBondContact O-CG 3.3Å; V209-E235 PolarHBondContact O-N 3.47Å; E235-P364 WeakPolarHBondContact O-CD 3.25Å
236Q98.7Very high96.1Very high10 Ų1024.8 Ų24.85%0.04713%0.126CC..EExtended strand (participates in β ladder)trans-156165.3175.756.6-178.9-21.900110.9T210 L211 P364 F520 V521 S524T210-Q236 WeakPolarHBondContact CA-O 3.32Å; T210-Q236 HydrophobicContact CG2-CG 3.99Å; T210-Q236 VanDerWaalsContact OG1-CG 3.27Å; T210-Q236 WeakPolarHBondContact OG1-CG 3.1Å; T210-Q236 PolarHBondContact OG1-NE2 3.14Å; L211-Q236 PolarHBondContact N-O 2.88Å; L211-Q236 VanDerWaalsContact N-O 3.07Å; Q236-P364 WeakPolarHBondContact CA-O 3.35Å; Q236-P364 HydrophobicContact CB-CB 3.86Å; Q236-P364 HydrophobicContact CB-CG 4.21Å; Q236-P364 VanDerWaalsContact CB-O 3.31Å; Q236-P364 WeakPolarHBondContact CB-O 3.15Å; Q236-F520 HydrophobicContact CB-CE1 4.36Å; Q236-F520 HydrophobicContact CB-CZ 4.3Å; Q236-F520 HydrophobicContact CG-CE1 4.33Å; Q236-F520 PolarHBondContact NE2-O 2.81Å; Q236-F520 VanDerWaalsContact OE1-CE1 3.24Å; Q236-F520 VanDerWaalsContact OE1-CZ 3.27Å; Q236-F520 PolarHBondContact OE1-O 3.46Å; Q236-V521 PolarHBondContact NE2-O 3.1Å; Q236-V521 VanDerWaalsContact NE2-O 3.08Å; Q236-S524 PolarHBondContact OE1-OG 3.45Å
237A98.9Very high95.3Very high0 Ų025.8 Ų25.80%013%0.133CC..EExtended strand (participates in β ladder)trans-137.9148-179.700000113.9L211 V221 T225 M363 P364 Y365 L366L211-A237 CarbonylContact O-C 3.6Å; L211-A237 WeakPolarHBondContact O-CA 3.42Å; V221-A237 HydrophobicContact CG1-CB 3.79Å; T225-A237 HydrophobicContact CG2-CB 4Å; A237-M363 HydrophobicContact CB-SD 4.29Å; A237-P364 PolarHBondContact N-O 3.19Å; A237-Y365 HydrophobicContact CB-CD2 3.78Å; A237-Y365 HydrophobicContact CB-CE2 3.73Å; A237-L366 PolarHBondContact O-N 3.44Å
238I98.9Very high94.5Very high0 Ų030.1 Ų30.10%015%0.149CC..EExtended strand (participates in β ladder)trans-119.8115.2174.7-60.8173000108.8T210 L211 M212 G213 M240 L366 L517 F520 V521T210-I238 HydrophobicContact CG2-CD1 3.8Å; T210-I238 HydrophobicContact CG2-CG1 3.8Å; L211-I238 PolarHBondContact O-N 3.34Å; M212-I238 CarbonylContact C-O 3.41Å; M212-I238 VanDerWaalsContact CA-O 3.3Å; M212-I238 WeakPolarHBondContact CA-O 3.29Å; M212-I238 HydrophobicContact CB-CB 4.06Å; M212-I238 HydrophobicContact CE-CG2 4.2Å; M212-I238 HydrophobicContact CG-CB 3.82Å; M212-I238 HydrophobicContact CG-CD1 4.44Å; M212-I238 HydrophobicContact CG-CG2 3.86Å; M212-I238 HydrophobicContact SD-CD1 4.2Å; M212-I238 HydrophobicContact SD-CG2 4.39Å; G213-I238 PolarHBondContact N-O 3.43Å; I238-M240 HydrophobicContact CG2-CG 4Å; I238-M240 HydrophobicContact CG2-SD 4.44Å; I238-L366 CarbonylContact C-O 3.44Å; I238-L366 VanDerWaalsContact CA-O 3.24Å; I238-L366 WeakPolarHBondContact CA-O 3.23Å; I238-L366 HydrophobicContact CG1-CB 4.27Å; I238-L366 HydrophobicContact CG2-CD2 4.17Å; I238-L517 HydrophobicContact CD1-CD2 4.24Å; I238-L517 HydrophobicContact CG2-CD2 4.11Å; I238-F520 HydrophobicContact CD1-CD1 3.85Å; I238-F520 HydrophobicContact CD1-CE1 4.29Å; I238-F520 HydrophobicContact CG1-CD1 3.67Å; I238-F520 HydrophobicContact CG1-CE1 3.63Å; I238-V521 HydrophobicContact CD1-CG2 3.86Å
239V98.7Very high94.2Very high0 Ų027.5 Ų27.50%013%0.132CC..EExtended strand (participates in β ladder)trans-117.9108.8-175178.30000110.8G218 V221 G242 Y365 L366 L367 G368G218-V239 WeakPolarHBondContact O-CG1 3.48Å; V221-V239 HydrophobicContact CB-CG2 4.11Å; V221-V239 HydrophobicContact CG1-CG2 3.64Å; V239-G242 WeakPolarHBondContact CG1-O 3.46Å; V239-Y365 HydrophobicContact CG2-CE2 3.75Å; V239-Y365 WeakPolarHBondContact CG2-OH 3.32Å; V239-L366 PolarHBondContact N-O 3.07Å; V239-L367 HydrophobicContact CB-CB 3.97Å; V239-L367 WeakPolarHBondContact O-CA 3.33Å; V239-L367 VanDerWaalsContact O-CB 3.32Å; V239-L367 WeakPolarHBondContact O-CB 3.49Å; V239-G368 PolarHBondContact O-N 2.76Å
240M98.2Very high93.7Very high0 Ų024.9 Ų24.90%012%0.121CC..EExtended strand (participates in β ladder)trans-107.1118.4-174.1-53177.168.100110.9M212 G213 H214 S215 I238 G242 D490 L491M212-M240 HydrophobicContact CE-SD 3.28Å; M212-M240 WeakPolarHBondContact CE-SD 3.49Å; G213-M240 PolarHBondContact O-N 2.03Å; H214-M240 CarbonylContact C-O 3.5Å; H214-M240 VanDerWaalsContact CA-O 3.23Å; H214-M240 WeakPolarHBondContact CA-O 3.34Å; H214-M240 HydrophobicContact CB-CB 4.13Å; S215-M240 PolarHBondContact N-O 3.39Å; I238-M240 HydrophobicContact CG2-CG 4Å; I238-M240 HydrophobicContact CG2-SD 4.44Å; M240-G242 PolarHBondContact O-N 2.87Å; M240-G242 VanDerWaalsContact O-N 3.16Å; M240-D490 HydrophobicContact CE-CB 3.84Å; M240-D490 WeakPolarHBondContact CE-OD2 2.93Å; M240-L491 HydrophobicContact CE-CD2 3.86Å; M240-L491 HydrophobicContact SD-CD2 3.94Å
241S96.1Very high92.8Very high0 Ų027.4 Ų27.40%013%0.133CC..SBendtrans52.440.6172.8-53.10000113.2S215 G368 E373S215-S241 WeakPolarHBondContact CA-O 3.46Å; S241-G368 PolarHBondContact N-O 3.03Å; S241-E373 WeakPolarHBondContact CB-OE1 3.4Å; S241-E373 PolarHBondContact OG-OE1 3.11Å; S241-E373 VanDerWaalsContact OG-OE1 3.05Å
242G94.6Very high91.9Very high0 Ų025.3 Ų25.30%013%0.125CC..  trans-163.3161.8-17900000111.2V239 M240 V456V239-G242 WeakPolarHBondContact CG1-O 3.46Å; M240-G242 PolarHBondContact O-N 2.87Å; M240-G242 VanDerWaalsContact O-N 3.16Å; G242-V456 WeakPolarHBondContact O-CG2 3.38Å
243S95.2Very high91Very high0 Ų022.6 Ų22.60%011%0.111CC..  trans-165.6151.3179.4157.70000110S219 L245 S246 A249 P455S219-S243 WeakPolarHBondContact CB-O 3.41Å; S219-S243 PolarHBondContact OG-N 3.3Å; S219-S243 VanDerWaalsContact OG-N 3.1Å; S219-S243 PolarHBondContact OG-O 2.96Å; S243-L245 PolarHBondContact O-N 2.9Å; S243-L245 PolarHBondContact OG-N 2.8Å; S243-S246 PolarHBondContact N-OG 2.84Å; S243-S246 VanDerWaalsContact N-OG 3.14Å; S243-S246 VanDerWaalsContact O-CB 3.29Å; S243-S246 WeakPolarHBondContact O-CB 3.37Å; S243-S246 PolarHBondContact O-N 3.15Å; S243-S246 PolarHBondContact O-OG 3Å; S243-A249 WeakPolarHBondContact O-CB 3.5Å; S243-P455 PolarHBondContact OG-O 2.93Å
244A93.5Very high90.1Very high0 Ų023.1 Ų23.10%011%0.113CC..THydrogen-bonded Turntrans-61-20.8171.200000113S222 L223 L226 A249 P353 M357S222-A244 VanDerWaalsContact CB-N 3.3Å; S222-A244 VanDerWaalsContact OG-CB 3.23Å; S222-A244 WeakPolarHBondContact OG-CB 3.48Å; S222-A244 PolarHBondContact OG-N 3.46Å; L223-A244 HydrophobicContact CD2-CB 3.57Å; L223-A244 HydrophobicContact CG-CB 3.76Å; L226-A244 HydrophobicContact CD1-CB 4.06Å; A244-A249 WeakPolarHBondContact O-CB 3.5Å; A244-P353 HydrophobicContact CB-CB 4.45Å; A244-M357 HydrophobicContact CB-CE 3.8Å
245L90.2Very high89.1Confident8 Ų824.1 Ų24.14%0.04212%0.12CC..THydrogen-bonded Turntrans-90.6-1.7176.1-58.9-179.3000113.1S243 I354 M357 W405 P455 A458S243-L245 PolarHBondContact O-N 2.9Å; S243-L245 PolarHBondContact OG-N 2.8Å; L245-I354 HydrophobicContact CD2-CG1 3.68Å; L245-M357 HydrophobicContact CD1-CE 4.15Å; L245-M357 HydrophobicContact CD1-SD 3.66Å; L245-M357 HydrophobicContact CD2-CE 4Å; L245-M357 HydrophobicContact CD2-SD 3.68Å; L245-M357 HydrophobicContact CG-CE 3.68Å; L245-M357 HydrophobicContact CG-SD 3.68Å; L245-W405 VanDerWaalsContact O-CH2 3.3Å; L245-W405 WeakPolarHBondContact O-CH2 3.27Å; L245-W405 WeakPolarHBondContact O-CZ2 3.46Å; L245-P455 HydrophobicContact CB-CB 4.03Å; L245-A458 HydrophobicContact CD1-CB 3.51Å
246S89.1Confident88.1Confident10 Ų1020.7 Ų20.77%0.0710%0.104CC..SBendtrans-67142.6-179-56.30000109.5S243 R248 A249S243-S246 PolarHBondContact N-OG 2.84Å; S243-S246 VanDerWaalsContact N-OG 3.14Å; S243-S246 VanDerWaalsContact O-CB 3.29Å; S243-S246 WeakPolarHBondContact O-CB 3.37Å; S243-S246 PolarHBondContact O-N 3.15Å; S243-S246 PolarHBondContact O-OG 3Å; S246-R248 PolarHBondContact O-N 2.71Å; S246-R248 VanDerWaalsContact O-N 3.16Å; S246-A249 WeakPolarHBondContact O-CB 3.43Å; S246-A249 PolarHBondContact O-N 3.22Å
247P80.3Confident87.5Confident32 Ų3220.9 Ų20.921%0.20811%0.105CC..THydrogen-bonded Turntrans-49126.8169.1-29.838000110.5A249 I404 N450 G451P247-A249 VanDerWaalsContact C-N 3.28Å; P247-A249 PolarHBondContact O-N 3Å; P247-I404 HydrophobicContact CB-CG2 4.07Å; P247-N450 WeakPolarHBondContact CD-O 3.47Å; P247-N450 WeakPolarHBondContact CG-O 3.39Å; P247-N450 WeakPolarHBondContact CG-OD1 3.16Å; P247-G451 WeakPolarHBondContact CD-O 3.36Å
248R79.6Confident86.7Confident92 Ų9225.5 Ų25.535%0.34713%0.128SC..THydrogen-bonded Turntrans69.114.1-177.6-45.2168.2177.6147.5-7.7115.4S246 F250 F334 F337 S339S246-R248 PolarHBondContact O-N 2.71Å; S246-R248 VanDerWaalsContact O-N 3.16Å; R248-F250 PolarHBondContact O-N 3.13Å; R248-F334 PolarHBondContact NH2-O 2.85Å; R248-F337 VanDerWaalsContact CZ-CE2 3.41Å; R248-F337 VanDerWaalsContact CZ-CZ 3.44Å; R248-F337 VanDerWaalsContact NH2-CE2 3.31Å; R248-S339 WeakPolarHBondContact O-CB 3.35Å
249A87.6Confident85.8Confident3 Ų326.5 Ų26.53%0.02513%0.134CC..SBendtrans-61.2-31.5165.900000111.2L223 S243 A244 S246 P247 P340L223-A249 WeakPolarHBondContact CD1-O 3.49Å; S243-A249 WeakPolarHBondContact O-CB 3.5Å; A244-A249 WeakPolarHBondContact O-CB 3.5Å; S246-A249 WeakPolarHBondContact O-CB 3.43Å; S246-A249 PolarHBondContact O-N 3.22Å; P247-A249 VanDerWaalsContact C-N 3.28Å; P247-A249 PolarHBondContact O-N 3Å; A249-P340 VanDerWaalsContact O-CD 3.31Å; A249-P340 WeakPolarHBondContact O-CD 3.15Å
250F86.5Confident85.2Confident43 Ų4326.5 Ų26.519%0.18913%0.134CC..  trans-145.8160.616970.4-79.4000111.8R248 S339 P340 I342 P353R248-F250 PolarHBondContact O-N 3.13Å; F250-S339 VanDerWaalsContact C-OG 3.26Å; F250-P340 CarbonylContact C-O 3.5Å; F250-P340 WeakPolarHBondContact CA-O 3.1Å; F250-P340 HydrophobicContact CB-CB 4.4Å; F250-P340 WeakPolarHBondContact CB-O 3.36Å; F250-I342 HydrophobicContact CD2-CG1 4.33Å; F250-I342 HydrophobicContact CE2-CD1 4.35Å; F250-I342 HydrophobicContact CE2-CG1 4.42Å; F250-P353 HydrophobicContact CD1-CG 3.74Å; F250-P353 HydrophobicContact CE1-CB 4.2Å; F250-P353 HydrophobicContact CE1-CG 3.66Å; F250-P353 HydrophobicContact CE2-CG 4.49Å; F250-P353 HydrophobicContact CG-CG 4.2Å; F250-P353 HydrophobicContact CZ-CG 4.07Å
251M79.2Confident84.7Confident52 Ų5226.7 Ų26.726%0.25614%0.135SC..  trans-145.6125.2178.3-173.8-178.9-60.600110D253 F337 S339 P340 R341M251-D253 HydrophobicContact CG-CB 4.16Å; M251-D253 HydrophobicContact SD-CB 4.41Å; M251-F337 HydrophobicContact CE-CB 4.37Å; M251-S339 WeakPolarHBondContact CB-OG 3.4Å; M251-S339 PolarHBondContact N-OG 2.88Å; M251-P340 PolarHBondContact N-O 2.71Å; M251-R341 WeakPolarHBondContact O-CB 3.3Å
252N74.9Confident84Confident58 Ų5829 Ų2931%0.3114%0.144SC..  trans-91.9-4.5179.3-63.1-22.2000113.8I342N252-I342 WeakPolarHBondContact ND2-CD1 3.18Å; N252-I342 VanDerWaalsContact OD1-CB 3.31Å; N252-I342 WeakPolarHBondContact OD1-CB 3.23Å; N252-I342 WeakPolarHBondContact OD1-CG1 3.3Å; N252-I342 PolarHBondContact OD1-N 2.83Å
253D75.6Confident83.3Confident67 Ų6733.7 Ų33.736%0.35816%0.162SC..  trans-88115179.4-178.714.4000110.6M251 T255M251-D253 HydrophobicContact CG-CB 4.16Å; M251-D253 HydrophobicContact SD-CB 4.41Å; D253-T255 WeakPolarHBondContact OD1-CB 3.46Å; D253-T255 PolarHBondContact OD1-N 3.44Å; D253-T255 PolarHBondContact OD1-OG1 2.91Å
254I80.4Confident83Confident31 Ų3134.8 Ų34.816%0.15917%0.167CC..  trans-91.5-2.9176.963.8162.8000113.1A175 P256 Y257 I258A175-I254 HydrophobicContact CB-CD1 3.88Å; A175-I254 HydrophobicContact CB-CG2 4.26Å; I254-P256 VanDerWaalsContact C-N 3.25Å; I254-P256 VanDerWaalsContact O-N 3.14Å; I254-Y257 PolarHBondContact O-N 2.92Å; I254-I258 HydrophobicContact CD1-CD1 3.89Å; I254-I258 HydrophobicContact CD1-CG1 4.32Å; I254-I258 HydrophobicContact CG1-CD1 3.97Å; I254-I258 HydrophobicContact CG1-CG1 4.45Å; I254-I258 PolarHBondContact O-N 3.19Å; I254-I258 VanDerWaalsContact O-N 3.14Å
255T76.6Confident82.6Confident23 Ų2336.9 Ų36.914%0.14119%0.19CC..Hα-helixtrans-46.1-44.8-179.9-65.10000112.9D253 Y257 I258 L259 L327 I331D253-T255 WeakPolarHBondContact OD1-CB 3.46Å; D253-T255 PolarHBondContact OD1-N 3.44Å; D253-T255 PolarHBondContact OD1-OG1 2.91Å; T255-Y257 VanDerWaalsContact C-N 3.3Å; T255-Y257 PolarHBondContact O-N 3Å; T255-I258 PolarHBondContact O-N 3.49Å; T255-L259 HydrophobicContact CG2-CD1 3.93Å; T255-L259 HydrophobicContact CG2-CG 4.34Å; T255-L259 WeakPolarHBondContact O-CG 3.18Å; T255-L259 PolarHBondContact O-N 3.36Å; T255-L327 HydrophobicContact CG2-CB 3.8Å; T255-L327 HydrophobicContact CG2-CD1 3.92Å; T255-L327 HydrophobicContact CG2-CD2 3.56Å; T255-L327 HydrophobicContact CG2-CG 3.93Å; T255-I331 HydrophobicContact CG2-CD1 4.32Å
256P78.2Confident82.4Confident6 Ų636.7 Ų36.74%0.03919%0.189CC..Hα-helixtrans-65.5-31.8-178.8-24.237.5000113.8I254 L259 L260 M299 F336I254-P256 VanDerWaalsContact C-N 3.25Å; I254-P256 VanDerWaalsContact O-N 3.14Å; P256-L259 PolarHBondContact O-N 2.95Å; P256-L260 WeakPolarHBondContact O-CB 3.42Å; P256-L260 PolarHBondContact O-N 3.46Å; P256-M299 HydrophobicContact CB-CE 4.5Å; P256-M299 VanDerWaalsContact O-CE 3.3Å; P256-M299 WeakPolarHBondContact O-CE 3.21Å; P256-F336 HydrophobicContact CB-CD2 3.06Å; P256-F336 HydrophobicContact CB-CE2 3.13Å; P256-F336 HydrophobicContact CB-CG 3.94Å; P256-F336 HydrophobicContact CB-CZ 3.98Å; P256-F336 HydrophobicContact CG-CD2 3.78Å; P256-F336 HydrophobicContact CG-CE2 4.12Å
257Y85.6Confident81.7Confident14 Ų1439.8 Ų39.86%0.05520%0.202CC..Hα-helixtrans-72.9-36.3174.8-62.7-53.1000112.2F171 F172 I254 T255 L259 L260 A261 F336 T338F171-Y257 WeakPolarHBondContact CB-OH 3.42Å; F171-Y257 WeakPolarHBondContact O-CE2 3.48Å; F171-Y257 PolarHBondContact O-OH 3.04Å; F171-Y257 VanDerWaalsContact O-OH 3.04Å; F172-Y257 AromaticContact CD2-CD1 3.92Å; F172-Y257 HydrophobicContact CD2-CD1 3.92Å; F172-Y257 AromaticContact CD2-CG 4Å; F172-Y257 HydrophobicContact CD2-CG 4Å; I254-Y257 PolarHBondContact O-N 2.92Å; T255-Y257 VanDerWaalsContact C-N 3.3Å; T255-Y257 PolarHBondContact O-N 3Å; Y257-L259 VanDerWaalsContact C-N 3.32Å; Y257-L260 PolarHBondContact O-N 2.65Å; Y257-A261 WeakPolarHBondContact O-CB 3.22Å; Y257-A261 PolarHBondContact O-N 3.4Å; Y257-F336 HydrophobicContact CD1-CE2 4.26Å; Y257-F336 AromaticContact CD1-CZ 3.97Å; Y257-F336 HydrophobicContact CD1-CZ 3.97Å; Y257-F336 HydrophobicContact CE1-CE2 4.02Å; Y257-F336 AromaticContact CE1-CZ 3.84Å; Y257-F336 HydrophobicContact CE1-CZ 3.84Å; Y257-T338 HydrophobicContact CE1-CG2 4.21Å; Y257-T338 VanDerWaalsContact OH-CG2 3.28Å; Y257-T338 WeakPolarHBondContact OH-CG2 3.09Å
258I81.8Confident80.7Confident97 Ų9741.3 Ų41.350%0.49721%0.212SC..Hα-helixtrans-60.9-45.6172.3-62.5173000110I254 T255 A261 Y262I254-I258 HydrophobicContact CD1-CD1 3.89Å; I254-I258 HydrophobicContact CD1-CG1 4.32Å; I254-I258 HydrophobicContact CG1-CD1 3.97Å; I254-I258 HydrophobicContact CG1-CG1 4.45Å; I254-I258 PolarHBondContact O-N 3.19Å; I254-I258 VanDerWaalsContact O-N 3.14Å; T255-I258 PolarHBondContact O-N 3.49Å; I258-A261 PolarHBondContact O-N 3.46Å; I258-Y262 WeakPolarHBondContact O-CB 3.16Å; I258-Y262 PolarHBondContact O-N 2.74Å
259L79.8Confident79.1Confident21 Ų2142 Ų4211%0.1122%0.222CC..Hα-helixtrans-65.2-39.2176.9-71.3172.4000111.9T255 P256 Y257 Y262 R263 M299 L324 L327 I331T255-L259 HydrophobicContact CG2-CD1 3.93Å; T255-L259 HydrophobicContact CG2-CG 4.34Å; T255-L259 WeakPolarHBondContact O-CG 3.18Å; T255-L259 PolarHBondContact O-N 3.36Å; P256-L259 PolarHBondContact O-N 2.95Å; Y257-L259 VanDerWaalsContact C-N 3.32Å; L259-Y262 WeakPolarHBondContact O-CB 3.42Å; L259-Y262 PolarHBondContact O-N 3.13Å; L259-R263 VanDerWaalsContact O-CG 3.3Å; L259-R263 WeakPolarHBondContact O-CG 3.42Å; L259-R263 PolarHBondContact O-N 2.98Å; L259-M299 HydrophobicContact CB-CE 3.83Å; L259-L324 HydrophobicContact CD2-CD1 3.73Å; L259-L327 HydrophobicContact CD1-CB 4.48Å; L259-I331 HydrophobicContact CD1-CD1 3.16Å
260L86.4Confident77.2Confident0 Ų046 Ų460%026%0.255CS..Hα-helixtrans-61.3-48.7174.7-179.861000111.5V168 P256 Y257 Y262 R263 L264 M284 L292 E295 Y296 M299V168-L260 HydrophobicContact CB-CD2 4.38Å; V168-L260 HydrophobicContact CG2-CD2 3.68Å; P256-L260 WeakPolarHBondContact O-CB 3.42Å; P256-L260 PolarHBondContact O-N 3.46Å; Y257-L260 PolarHBondContact O-N 2.65Å; L260-Y262 VanDerWaalsContact C-N 3.28Å; L260-Y262 PolarHBondContact O-N 3.27Å; L260-R263 WeakPolarHBondContact O-CB 3.39Å; L260-R263 PolarHBondContact O-N 2.68Å; L260-R263 VanDerWaalsContact O-N 3.1Å; L260-L264 HydrophobicContact CD1-CD1 3.75Å; L260-L264 HydrophobicContact CD1-CG 4.37Å; L260-L264 HydrophobicContact CG-CD1 3.78Å; L260-L264 WeakPolarHBondContact O-CD1 3.39Å; L260-L264 WeakPolarHBondContact O-CG 3.33Å; L260-L264 PolarHBondContact O-N 2.93Å; L260-M284 HydrophobicContact CD2-CE 4.49Å; L260-M284 HydrophobicContact CG-CE 4.44Å; L260-L292 HydrophobicContact CD2-CD1 4.22Å; L260-E295 HydrophobicContact CD1-CB 4.03Å; L260-Y296 HydrophobicContact CD2-CD2 3.99Å; L260-M299 VanDerWaalsContact CA-SD 3.6Å; L260-M299 HydrophobicContact CB-CE 4.45Å; L260-M299 HydrophobicContact CB-SD 3.77Å; L260-M299 HydrophobicContact CD1-SD 3.87Å; L260-M299 HydrophobicContact CG-SD 4.43Å
261A87.1Confident74.9Confident4 Ų452.2 Ų52.23%0.03329%0.29CS..Hα-helixtrans-57.6-43.7176.200000111.4Y257 I258 R263 L264 G265 C266 V280 M284Y257-A261 WeakPolarHBondContact O-CB 3.22Å; Y257-A261 PolarHBondContact O-N 3.4Å; I258-A261 PolarHBondContact O-N 3.46Å; A261-R263 PolarHBondContact O-N 2.86Å; A261-L264 PolarHBondContact O-N 3.2Å; A261-G265 PolarHBondContact O-N 2.93Å; A261-C266 HydrophobicContact CB-CB 4.13Å; A261-C266 WeakPolarHBondContact O-CA 3.15Å; A261-C266 WeakPolarHBondContact O-CB 3.47Å; A261-C266 PolarHBondContact O-N 3.45Å; A261-V280 HydrophobicContact CB-CG1 4.03Å; A261-M284 VanDerWaalsContact CA-SD 3.58Å; A261-M284 HydrophobicContact CB-CE 4.48Å; A261-M284 HydrophobicContact CB-CG 4.25Å; A261-M284 HydrophobicContact CB-SD 3.73Å
262Y81.7Confident73.1Confident47 Ų4753.1 Ų53.118%0.18431%0.306CS..Hα-helixtrans-57.9-47.9173.8-172.2-78.7000111.8I258 L259 L260 L264 G265 H267 L315 F320I258-Y262 WeakPolarHBondContact O-CB 3.16Å; I258-Y262 PolarHBondContact O-N 2.74Å; L259-Y262 WeakPolarHBondContact O-CB 3.42Å; L259-Y262 PolarHBondContact O-N 3.13Å; L260-Y262 VanDerWaalsContact C-N 3.28Å; L260-Y262 PolarHBondContact O-N 3.27Å; Y262-L264 PolarHBondContact O-N 3.3Å; Y262-G265 PolarHBondContact O-N 2.52Å; Y262-G265 VanDerWaalsContact O-N 3.07Å; Y262-H267 AromaticContact CD1-CE1 3.44Å; Y262-H267 VanDerWaalsContact CD1-CE1 3.44Å; Y262-H267 WeakPolarHBondContact CD1-CE1 3.22Å; Y262-H267 AromaticContact CD1-ND1 3.97Å; Y262-H267 AromaticContact CD2-CE1 3.29Å; Y262-H267 WeakPolarHBondContact CD2-CE1 3.46Å; Y262-H267 AromaticContact CD2-ND1 2.93Å; Y262-H267 WeakPolarHBondContact CD2-ND1 3.36Å; Y262-H267 AromaticContact CE1-CE1 3.5Å; Y262-H267 AromaticContact CE2-CE1 3.37Å; Y262-H267 WeakPolarHBondContact CE2-CE1 3.42Å; Y262-H267 AromaticContact CE2-ND1 3.18Å; Y262-H267 WeakPolarHBondContact CE2-ND1 3.37Å; Y262-H267 AromaticContact CG-CE1 3.29Å; Y262-H267 AromaticContact CG-ND1 3.34Å; Y262-H267 VanDerWaalsContact CG-ND1 3.34Å; Y262-H267 AromaticContact CZ-CE1 3.46Å; Y262-H267 VanDerWaalsContact CZ-CE1 3.46Å; Y262-H267 AromaticContact CZ-ND1 3.8Å; Y262-H267 PolarHBondContact O-CE1 2.75Å; Y262-H267 PolarHBondContact O-NE2 3.2Å; Y262-L315 HydrophobicContact CE1-CD1 3.65Å; Y262-L315 HydrophobicContact CE1-CD2 3.93Å; Y262-L315 HydrophobicContact CE1-CG 4.42Å; Y262-L315 VanDerWaalsContact OH-CD2 3.29Å; Y262-L315 WeakPolarHBondContact OH-CD2 3.21Å; Y262-F320 HydrophobicContact CE2-CD1 4.3Å; Y262-F320 HydrophobicContact CE2-CE1 4.36Å
263R80Confident71.5Confident99 Ų9961.2 Ų61.237%0.37434%0.339SS..Hα-helixtrans-62.2-30.2179.8-71-17882.981.712.7113.4L259 L260 A261 G265 E295 M299 I304L259-R263 VanDerWaalsContact O-CG 3.3Å; L259-R263 WeakPolarHBondContact O-CG 3.42Å; L259-R263 PolarHBondContact O-N 2.98Å; L260-R263 WeakPolarHBondContact O-CB 3.39Å; L260-R263 PolarHBondContact O-N 2.68Å; L260-R263 VanDerWaalsContact O-N 3.1Å; A261-R263 PolarHBondContact O-N 2.86Å; R263-G265 PolarHBondContact O-N 2.85Å; R263-E295 IonicContact CZ-OE2 2.89Å; R263-E295 IonicContact NE-OE2 3.67Å; R263-E295 PolarHBondContact NE-OE2 3.22Å; R263-E295 IonicContact NH2-OE2 2.94Å; R263-M299 VanDerWaalsContact CD-SD 3.54Å; R263-I304 VanDerWaalsContact CZ-CG1 3.46Å; R263-I304 VanDerWaalsContact NH1-CG1 3.35Å
264L88.2Confident70Confident23 Ų2366.6 Ų66.612%0.1236%0.359CS..THydrogen-bonded Turntrans-85.12.4-180-69.5161.8000113L260 A261 Y262 C266 M284 I287 Q291 L292 E295L260-L264 HydrophobicContact CD1-CD1 3.75Å; L260-L264 HydrophobicContact CD1-CG 4.37Å; L260-L264 HydrophobicContact CG-CD1 3.78Å; L260-L264 WeakPolarHBondContact O-CD1 3.39Å; L260-L264 WeakPolarHBondContact O-CG 3.33Å; L260-L264 PolarHBondContact O-N 2.93Å; A261-L264 PolarHBondContact O-N 3.2Å; Y262-L264 PolarHBondContact O-N 3.3Å; L264-C266 VanDerWaalsContact C-N 3.31Å; L264-M284 HydrophobicContact CD1-CE 3.91Å; L264-M284 HydrophobicContact CD1-SD 4Å; L264-I287 HydrophobicContact CB-CD1 3.5Å; L264-I287 HydrophobicContact CD1-CD1 3.57Å; L264-I287 HydrophobicContact CD2-CD1 4.1Å; L264-I287 HydrophobicContact CD2-CG2 4.22Å; L264-I287 HydrophobicContact CG-CD1 3.89Å; L264-Q291 HydrophobicContact CD2-CG 4.23Å; L264-L292 HydrophobicContact CD1-CD1 3.49Å; L264-L292 VanDerWaalsContact CD1-CD1 3.49Å; L264-E295 HydrophobicContact CD2-CB 3.98Å; L264-E295 HydrophobicContact CD2-CG 3.98Å; L264-E295 HydrophobicContact CG-CB 4.43Å
265G86.1Confident69Low45 Ų4571.5 Ų71.546%0.46438%0.381SS..THydrogen-bonded Turntrans83.84.5-179.100000114.1A261 Y262 R263 H267A261-G265 PolarHBondContact O-N 2.93Å; Y262-G265 PolarHBondContact O-N 2.52Å; Y262-G265 VanDerWaalsContact O-N 3.07Å; R263-G265 PolarHBondContact O-N 2.85Å; G265-H267 VanDerWaalsContact C-N 3.27Å; G265-H267 PolarHBondContact O-CD2 3.19Å; G265-H267 PolarHBondContact O-N 2.87Å
266C87Confident68.9Low4 Ų474.6 Ų74.63%0.02740%0.397CS..  trans-8469.5176.4-59.20000110.6A261 L264 V280 C283 M284A261-C266 HydrophobicContact CB-CB 4.13Å; A261-C266 WeakPolarHBondContact O-CA 3.15Å; A261-C266 WeakPolarHBondContact O-CB 3.47Å; A261-C266 PolarHBondContact O-N 3.45Å; L264-C266 VanDerWaalsContact C-N 3.31Å; C266-V280 HydrophobicContact CB-CG1 4.31Å; C266-C283 WeakPolarHBondContact CA-SG 2.81Å; C266-C283 HydrophobicContact CB-CB 3.68Å; C266-C283 WeakPolarHBondContact CB-SG 3.46Å; C266-C283 WeakPolarHBondContact SG-CB 3.36Å; C266-C283 CovalentContact SG-SG 2.04Å; C266-C283 PolarHBondContact SG-SG 3.31Å; C266-M284 HydrophobicContact CB-CG 4.2Å; C266-M284 HydrophobicContact CB-SD 4.05Å
267H73.5Confident69.2Low74 Ų7477.2 Ų77.234%0.34341%0.41SS..  trans-92.8140.2180-52-71.6000111.7Y262 G265 L269Y262-H267 AromaticContact CD1-CE1 3.44Å; Y262-H267 VanDerWaalsContact CD1-CE1 3.44Å; Y262-H267 WeakPolarHBondContact CD1-CE1 3.22Å; Y262-H267 AromaticContact CD1-ND1 3.97Å; Y262-H267 AromaticContact CD2-CE1 3.29Å; Y262-H267 WeakPolarHBondContact CD2-CE1 3.46Å; Y262-H267 AromaticContact CD2-ND1 2.93Å; Y262-H267 WeakPolarHBondContact CD2-ND1 3.36Å; Y262-H267 AromaticContact CE1-CE1 3.5Å; Y262-H267 AromaticContact CE2-CE1 3.37Å; Y262-H267 WeakPolarHBondContact CE2-CE1 3.42Å; Y262-H267 AromaticContact CE2-ND1 3.18Å; Y262-H267 WeakPolarHBondContact CE2-ND1 3.37Å; Y262-H267 AromaticContact CG-CE1 3.29Å; Y262-H267 AromaticContact CG-ND1 3.34Å; Y262-H267 VanDerWaalsContact CG-ND1 3.34Å; Y262-H267 AromaticContact CZ-CE1 3.46Å; Y262-H267 VanDerWaalsContact CZ-CE1 3.46Å; Y262-H267 AromaticContact CZ-ND1 3.8Å; Y262-H267 PolarHBondContact O-CE1 2.75Å; Y262-H267 PolarHBondContact O-NE2 3.2Å; G265-H267 VanDerWaalsContact C-N 3.27Å; G265-H267 PolarHBondContact O-CD2 3.19Å; G265-H267 PolarHBondContact O-N 2.87Å; H267-L269 PolarHBondContact O-N 2.91Å
268P58.7Low69.4Low64 Ų6478.9 Ų78.942%0.41642%0.423SS..SBendtrans-66.80.1170.9-17.527.9000115.3H275 V280P268-H275 HydrophobicContact CB-CB 4.37Å; P268-V280 HydrophobicContact CB-CG2 4.39Å; P268-V280 HydrophobicContact CG-CG2 3.91Å
269L46.5Very low69.7Low106 Ų10676.6 Ų76.656%0.55542%0.419SS*.  trans-105.796.7-166.6-72.6170.1000112.3H267 F320H267-L269 PolarHBondContact O-N 2.91Å; L269-F320 HydrophobicContact CD1-CE2 3.98Å; L269-F320 HydrophobicContact CD1-CZ 3.68Å
270A47.1Very low70.1Confident88 Ų8876.3 Ų76.373%0.72742%0.418SS*.SBendtrans-133.8-40.6150.900000114.7
271N37.9Very low70.4Confident174 Ų17476.3 Ų76.393%0.9342%0.418SS*.SBendtrans-17526.8177.4-103.3-20.7000119.3
272A42.3Very low70.7Confident70 Ų7081 Ų8158%0.57944%0.439SS*.  trans-133.1128.8-179.100000113K274A272-K274 CarbonylContact O-C 3.42Å; A272-K274 PolarHBondContact O-N 2.98Å
273F40.6Very low71.2Confident229 Ų22981 Ų81100%1.00445%0.445SS*.SBendtrans-64.418.3173.2-86.4-90.9000114.7
274K45.5Very low71.9Confident180 Ų18076.2 Ų76.278%0.78343%0.428SS*.SBendtrans-128.1110.6160.5-93.4179.9171.8-179.50105A272 N276A272-K274 CarbonylContact O-C 3.42Å; A272-K274 PolarHBondContact O-N 2.98Å; K274-N276 PolarHBondContact O-N 2.92Å
275H57.9Low72.3Confident134 Ų13477.1 Ų77.162%0.6243%0.429SS*.  trans-47.9108.6165.8-64.1-69.2000107.3P268 I277P268-H275 HydrophobicContact CB-CB 4.37Å; H275-I277 PolarHBondContact O-N 2.85Å
276N76.2Confident72.8Confident88 Ų8878.9 Ų78.947%0.47144%0.44SS..  trans-77.480.5179.9-173.2-9.7000106.6K274 S278 A279 V280K274-N276 PolarHBondContact O-N 2.92Å; N276-S278 PolarHBondContact O-N 3.4Å; N276-S278 WeakPolarHBondContact OD1-CB 3.3Å; N276-S278 PolarHBondContact OD1-N 3.23Å; N276-A279 HydrophobicContact CB-CB 3.86Å; N276-A279 VanDerWaalsContact CG-CB 3.49Å; N276-A279 WeakPolarHBondContact O-CA 3.2Å; N276-A279 WeakPolarHBondContact O-CB 3.28Å; N276-A279 PolarHBondContact O-N 2.95Å; N276-A279 PolarHBondContact OD1-N 3.22Å; N276-V280 PolarHBondContact O-N 2.68Å
277I84.6Confident73.2Confident60 Ų6079.4 Ų79.431%0.30844%0.442SS..Hα-helixtrans-56.4-38179.6-61.7170000109.1T174 S176 H275 A279 V280 V281T174-I277 HydrophobicContact CG2-CG2 4.06Å; S176-I277 VanDerWaalsContact OG-CG2 3.23Å; S176-I277 WeakPolarHBondContact OG-CG2 3.26Å; H275-I277 PolarHBondContact O-N 2.85Å; I277-A279 VanDerWaalsContact C-N 3.3Å; I277-A279 PolarHBondContact O-N 2.94Å; I277-V280 WeakPolarHBondContact O-CA 3.21Å; I277-V280 WeakPolarHBondContact O-CB 3.23Å; I277-V280 PolarHBondContact O-N 2.99Å; I277-V281 HydrophobicContact CG2-CG2 4.34Å; I277-V281 WeakPolarHBondContact O-CG2 3.26Å; I277-V281 PolarHBondContact O-N 2.8Å
278S88.5Confident74.3Confident49 Ų4979 Ų7934%0.34345%0.446SS..Hα-helixtrans-55.9-42.6173.5-29.30000111.8E178 N276 V280 V281 E282E178-S278 PolarHBondContact OE1-OG 3.33Å; N276-S278 PolarHBondContact O-N 3.4Å; N276-S278 WeakPolarHBondContact OD1-CB 3.3Å; N276-S278 PolarHBondContact OD1-N 3.23Å; S278-V280 VanDerWaalsContact C-N 3.34Å; S278-V280 PolarHBondContact O-N 2.74Å; S278-V281 PolarHBondContact O-N 3.19Å; S278-E282 WeakPolarHBondContact O-CB 3.33Å; S278-E282 WeakPolarHBondContact O-CG 3.34Å; S278-E282 PolarHBondContact O-N 3.19Å
279A88.1Confident76Confident49 Ų4976.2 Ų76.241%0.40543%0.428SS..Hα-helixtrans-65.6-33.1174.800000113.5N276 I277 C283N276-A279 HydrophobicContact CB-CB 3.86Å; N276-A279 VanDerWaalsContact CG-CB 3.49Å; N276-A279 WeakPolarHBondContact O-CA 3.2Å; N276-A279 WeakPolarHBondContact O-CB 3.28Å; N276-A279 PolarHBondContact O-N 2.95Å; N276-A279 PolarHBondContact OD1-N 3.22Å; I277-A279 VanDerWaalsContact C-N 3.3Å; I277-A279 PolarHBondContact O-N 2.94Å; A279-C283 VanDerWaalsContact O-CB 3.22Å; A279-C283 WeakPolarHBondContact O-CB 3.47Å; A279-C283 PolarHBondContact O-N 3.36Å
280V89Confident78.2Confident16 Ų1676 Ų7610%0.09743%0.428CS..Hα-helixtrans-66.3-47.4173.5178.40000110A261 C266 P268 N276 I277 S278 C283 M284A261-V280 HydrophobicContact CB-CG1 4.03Å; C266-V280 HydrophobicContact CB-CG1 4.31Å; P268-V280 HydrophobicContact CB-CG2 4.39Å; P268-V280 HydrophobicContact CG-CG2 3.91Å; N276-V280 PolarHBondContact O-N 2.68Å; I277-V280 WeakPolarHBondContact O-CA 3.21Å; I277-V280 WeakPolarHBondContact O-CB 3.23Å; I277-V280 PolarHBondContact O-N 2.99Å; S278-V280 VanDerWaalsContact C-N 3.34Å; S278-V280 PolarHBondContact O-N 2.74Å; V280-C283 WeakPolarHBondContact O-CB 3.09Å; V280-C283 PolarHBondContact O-N 2.71Å; V280-M284 HydrophobicContact CG1-CG 4.46Å; V280-M284 VanDerWaalsContact O-CG 3.24Å; V280-M284 WeakPolarHBondContact O-CG 3.41Å; V280-M284 PolarHBondContact O-N 3.32Å
281V92.4Very high80.4Confident0 Ų076.4 Ų76.40%041%0.414CS..Hα-helixtrans-63.8-43.6178.9177.80000111.2F172 T174 E178 A179 I277 S278 C283 M284 R285F172-V281 HydrophobicContact CE1-CG2 4.41Å; T174-V281 HydrophobicContact CG2-CG2 4.01Å; E178-V281 HydrophobicContact CB-CB 4.34Å; E178-V281 HydrophobicContact CB-CG2 3.86Å; A179-V281 HydrophobicContact CB-CG1 4.22Å; A179-V281 HydrophobicContact CB-CG2 3.69Å; I277-V281 HydrophobicContact CG2-CG2 4.34Å; I277-V281 WeakPolarHBondContact O-CG2 3.26Å; I277-V281 PolarHBondContact O-N 2.8Å; S278-V281 PolarHBondContact O-N 3.19Å; V281-C283 VanDerWaalsContact C-N 3.35Å; V281-C283 PolarHBondContact O-N 2.81Å; V281-M284 CarbonylContact O-C 3.43Å; V281-M284 WeakPolarHBondContact O-CB 3.26Å; V281-M284 PolarHBondContact O-N 3.44Å; V281-M284 VanDerWaalsContact O-N 3.16Å; V281-R285 HydrophobicContact CG1-CG 4.45Å; V281-R285 WeakPolarHBondContact O-CG 3.44Å; V281-R285 PolarHBondContact O-N 2.64Å
282E92.6Very high83Confident101 Ų10168.1 Ų68.147%0.47237%0.37SS..Hα-helixtrans-62.2-41.3175.2-73.4-54.1126.800112.1S278 M284 R285 A286S278-E282 WeakPolarHBondContact O-CB 3.33Å; S278-E282 WeakPolarHBondContact O-CG 3.34Å; S278-E282 PolarHBondContact O-N 3.19Å; E282-M284 VanDerWaalsContact C-N 3.34Å; E282-M284 PolarHBondContact O-N 3.2Å; E282-R285 PolarHBondContact O-N 3.05Å; E282-R285 IonicContact OE1-CZ 3.67Å; E282-R285 IonicContact OE1-NH1 2.75Å; E282-R285 PolarHBondContact OE1-NH1 2.91Å; E282-A286 PolarHBondContact O-N 2.88Å; E282-A286 VanDerWaalsContact O-N 3.08Å
283C93.6Very high85.3Confident47 Ų4765.2 Ų65.232%0.31835%0.345SS..Hα-helixtrans-58.6-47.5172.11770000110.8C266 A279 V280 V281 R285 A286 I287C266-C283 WeakPolarHBondContact CA-SG 2.81Å; C266-C283 HydrophobicContact CB-CB 3.68Å; C266-C283 WeakPolarHBondContact CB-SG 3.46Å; C266-C283 WeakPolarHBondContact SG-CB 3.36Å; C266-C283 CovalentContact SG-SG 2.04Å; C266-C283 PolarHBondContact SG-SG 3.31Å; A279-C283 VanDerWaalsContact O-CB 3.22Å; A279-C283 WeakPolarHBondContact O-CB 3.47Å; A279-C283 PolarHBondContact O-N 3.36Å; V280-C283 WeakPolarHBondContact O-CB 3.09Å; V280-C283 PolarHBondContact O-N 2.71Å; V281-C283 VanDerWaalsContact C-N 3.35Å; V281-C283 PolarHBondContact O-N 2.81Å; C283-R285 VanDerWaalsContact C-N 3.33Å; C283-R285 PolarHBondContact O-N 3.16Å; C283-A286 PolarHBondContact O-N 3.49Å; C283-A286 VanDerWaalsContact O-N 3.12Å; C283-I287 WeakPolarHBondContact O-CG1 3.45Å; C283-I287 PolarHBondContact O-N 3.16Å
284M94.6Very high87.6Confident0 Ų060.7 Ų60.70%032%0.322CS..Hα-helixtrans-63.1-36.7178.3-68.7-66.1-69.100112.5F67 F172 L260 A261 L264 C266 V280 V281 E282 A286 I287 L292F67-M284 HydrophobicContact CD2-CB 4.33Å; F67-M284 HydrophobicContact CE2-CB 3.76Å; F172-M284 HydrophobicContact CD2-CE 4.09Å; F172-M284 HydrophobicContact CE1-CB 4.41Å; F172-M284 HydrophobicContact CE1-CG 4.38Å; F172-M284 HydrophobicContact CE2-CE 3.75Å; F172-M284 HydrophobicContact CE2-CG 4.3Å; F172-M284 HydrophobicContact CZ-CB 4.33Å; F172-M284 HydrophobicContact CZ-CE 4.2Å; F172-M284 HydrophobicContact CZ-CG 3.82Å; L260-M284 HydrophobicContact CD2-CE 4.49Å; L260-M284 HydrophobicContact CG-CE 4.44Å; A261-M284 VanDerWaalsContact CA-SD 3.58Å; A261-M284 HydrophobicContact CB-CE 4.48Å; A261-M284 HydrophobicContact CB-CG 4.25Å; A261-M284 HydrophobicContact CB-SD 3.73Å; L264-M284 HydrophobicContact CD1-CE 3.91Å; L264-M284 HydrophobicContact CD1-SD 4Å; C266-M284 HydrophobicContact CB-CG 4.2Å; C266-M284 HydrophobicContact CB-SD 4.05Å; V280-M284 HydrophobicContact CG1-CG 4.46Å; V280-M284 VanDerWaalsContact O-CG 3.24Å; V280-M284 WeakPolarHBondContact O-CG 3.41Å; V280-M284 PolarHBondContact O-N 3.32Å; V281-M284 CarbonylContact O-C 3.43Å; V281-M284 WeakPolarHBondContact O-CB 3.26Å; V281-M284 PolarHBondContact O-N 3.44Å; V281-M284 VanDerWaalsContact O-N 3.16Å; E282-M284 VanDerWaalsContact C-N 3.34Å; E282-M284 PolarHBondContact O-N 3.2Å; M284-A286 VanDerWaalsContact C-N 3.29Å; M284-A286 PolarHBondContact O-N 3.41Å; M284-I287 HydrophobicContact CE-CD1 4.5Å; M284-I287 PolarHBondContact O-N 3.23Å; M284-I287 HydrophobicContact SD-CD1 3.69Å; M284-L292 HydrophobicContact CE-CD1 3.68Å
285R95.8Very high89.5Confident42 Ų4253.4 Ų53.416%0.15829%0.291CS..Hα-helixtrans-63.3-33.8174.1-75.5178.5172.9133.79.2112.4P64 R66 F67 V281 E282 C283 I287P64-R285 PolarHBondContact O-NE 2.79Å; R66-R285 HydrophobicContact CB-CG 4.31Å; R66-R285 PolarHBondContact NH1-O 3.04Å; R66-R285 PolarHBondContact O-NE 2.79Å; R66-R285 PolarHBondContact O-NH2 3.46Å; F67-R285 HydrophobicContact CD2-CG 4.07Å; F67-R285 PolarHBondContact O-NH2 3.28Å; V281-R285 HydrophobicContact CG1-CG 4.45Å; V281-R285 WeakPolarHBondContact O-CG 3.44Å; V281-R285 PolarHBondContact O-N 2.64Å; E282-R285 PolarHBondContact O-N 3.05Å; E282-R285 IonicContact OE1-CZ 3.67Å; E282-R285 IonicContact OE1-NH1 2.75Å; E282-R285 PolarHBondContact OE1-NH1 2.91Å; C283-R285 VanDerWaalsContact C-N 3.33Å; C283-R285 PolarHBondContact O-N 3.16Å; R285-I287 VanDerWaalsContact C-N 3.34Å
286A95.8Very high91Very high82 Ų8247.2 Ų47.268%0.67826%0.262SS*.Hα-helixtrans-77.9-13.8-178.500000114.4E282 C283 M284E282-A286 PolarHBondContact O-N 2.88Å; E282-A286 VanDerWaalsContact O-N 3.08Å; C283-A286 PolarHBondContact O-N 3.49Å; C283-A286 VanDerWaalsContact O-N 3.12Å; M284-A286 VanDerWaalsContact C-N 3.29Å; M284-A286 PolarHBondContact O-N 3.41Å
287I96Very high91.4Very high14 Ų1443.8 Ų43.87%0.07224%0.244CC..SBendtrans-71.5132.5-177.9-56.5173.2000110.2R66 L264 C283 M284 R285 Q291 L292R66-I287 PolarHBondContact NH1-O 3.42Å; L264-I287 HydrophobicContact CB-CD1 3.5Å; L264-I287 HydrophobicContact CD1-CD1 3.57Å; L264-I287 HydrophobicContact CD2-CD1 4.1Å; L264-I287 HydrophobicContact CD2-CG2 4.22Å; L264-I287 HydrophobicContact CG-CD1 3.89Å; C283-I287 WeakPolarHBondContact O-CG1 3.45Å; C283-I287 PolarHBondContact O-N 3.16Å; M284-I287 HydrophobicContact CE-CD1 4.5Å; M284-I287 PolarHBondContact O-N 3.23Å; M284-I287 HydrophobicContact SD-CD1 3.69Å; R285-I287 VanDerWaalsContact C-N 3.34Å; I287-Q291 HydrophobicContact CG2-CB 4.04Å; I287-Q291 HydrophobicContact CG2-CG 4.12Å; I287-L292 HydrophobicContact CB-CB 4.47Å; I287-L292 HydrophobicContact CG2-CB 3.89Å
288P96.3Very high91.2Very high66 Ų6643.5 Ų43.543%0.42924%0.241SC..  trans-55139.5170.4-27.136.8000112.5D290 Q291 L292P288-D290 VanDerWaalsContact C-N 3.28Å; P288-D290 WeakPolarHBondContact CB-OD1 3.42Å; P288-D290 PolarHBondContact O-N 2.59Å; P288-Q291 HydrophobicContact CB-CB 4.32Å; P288-Q291 PolarHBondContact O-N 3.32Å; P288-Q291 VanDerWaalsContact O-N 3.13Å; P288-L292 PolarHBondContact O-N 3.35Å
289A94.7Very high90.7Very high6 Ų641.7 Ų41.75%0.0523%0.227CC..Hα-helixtrans-60.7-36.8-173.100000113.3W91 E105 F169 L292 D293W91-A289 HydrophobicContact CD2-CB 3.59Å; W91-A289 HydrophobicContact CE3-CB 3.59Å; W91-A289 HydrophobicContact CG-CB 4.31Å; W91-A289 HydrophobicContact CH2-CB 3.82Å; W91-A289 HydrophobicContact CZ2-CB 3.84Å; W91-A289 HydrophobicContact CZ3-CB 3.7Å; W91-A289 PolarHBondContact NE1-O 2.95Å; E105-A289 HydrophobicContact CG-CB 4.15Å; E105-A289 WeakPolarHBondContact OE2-CB 3.2Å; F169-A289 HydrophobicContact CE1-CB 3.87Å; F169-A289 HydrophobicContact CZ-CB 3.73Å; A289-L292 PolarHBondContact O-N 3.38Å; A289-D293 WeakPolarHBondContact O-CB 3.4Å; A289-D293 PolarHBondContact O-N 3.35Å
290D92.3Very high90.2Very high102 Ų10240.3 Ų40.355%0.54521%0.212SC..Hα-helixtrans-64.2-42.7175.863-40.6000112.3W91 P288 Y294W91-D290 HydrophobicContact CH2-CB 4.22Å; W91-D290 VanDerWaalsContact CZ2-CA 3.46Å; W91-D290 HydrophobicContact CZ2-CB 3.71Å; W91-D290 VanDerWaalsContact CZ2-N 3.27Å; P288-D290 VanDerWaalsContact C-N 3.28Å; P288-D290 WeakPolarHBondContact CB-OD1 3.42Å; P288-D290 PolarHBondContact O-N 2.59Å; D290-Y294 WeakPolarHBondContact O-CB 3.45Å; D290-Y294 PolarHBondContact O-N 3.43Å
291Q92.9Very high89.4Confident95 Ų9543.1 Ų43.144%0.44423%0.227SC..Hα-helixtrans-67.1-44.4176.4-176.9-179.1-1.900111.6L264 I287 P288 Y294 E295L264-Q291 HydrophobicContact CD2-CG 4.23Å; I287-Q291 HydrophobicContact CG2-CB 4.04Å; I287-Q291 HydrophobicContact CG2-CG 4.12Å; P288-Q291 HydrophobicContact CB-CB 4.32Å; P288-Q291 PolarHBondContact O-N 3.32Å; P288-Q291 VanDerWaalsContact O-N 3.13Å; Q291-Y294 PolarHBondContact O-N 2.93Å; Q291-E295 PolarHBondContact O-N 2.88Å; Q291-E295 VanDerWaalsContact O-N 3.13Å
292L93.4Very high87.9Confident0 Ų044.5 Ų44.50%024%0.241CC..Hα-helixtrans-60.4-49.9178.4175.360000111F67 V168 F169 L260 L264 M284 I287 P288 A289 Y296F67-L292 HydrophobicContact CZ-CD2 3.74Å; V168-L292 HydrophobicContact CG1-CD1 4.29Å; V168-L292 HydrophobicContact CG1-CD2 3.98Å; V168-L292 HydrophobicContact CG1-CG 3.78Å; V168-L292 HydrophobicContact CG2-CD1 4.01Å; V168-L292 HydrophobicContact CG2-CD2 4.35Å; V168-L292 HydrophobicContact CG2-CG 4.33Å; F169-L292 HydrophobicContact CD1-CD2 4.24Å; F169-L292 HydrophobicContact CE1-CD2 3.65Å; F169-L292 HydrophobicContact CZ-CB 4.44Å; F169-L292 HydrophobicContact CZ-CD2 3.86Å; F169-L292 HydrophobicContact CZ-CG 4.29Å; L260-L292 HydrophobicContact CD2-CD1 4.22Å; L264-L292 HydrophobicContact CD1-CD1 3.49Å; L264-L292 VanDerWaalsContact CD1-CD1 3.49Å; M284-L292 HydrophobicContact CE-CD1 3.68Å; I287-L292 HydrophobicContact CB-CB 4.47Å; I287-L292 HydrophobicContact CG2-CB 3.89Å; P288-L292 PolarHBondContact O-N 3.35Å; A289-L292 PolarHBondContact O-N 3.38Å; L292-Y296 WeakPolarHBondContact O-CB 3.28Å; L292-Y296 PolarHBondContact O-N 3.25Å
293D90.9Very high85.8Confident10 Ų1045.7 Ų45.75%0.05325%0.248CC..Hα-helixtrans-66.6-35.9179.1-173.218.7000112.5W91 N93 F169 A289 Y296 T297W91-D293 PolarHBondContact NE1-OD2 2.95Å; N93-D293 WeakPolarHBondContact CB-OD2 2.99Å; N93-D293 PolarHBondContact N-OD2 2.88Å; F169-D293 HydrophobicContact CE2-CB 4.17Å; A289-D293 WeakPolarHBondContact O-CB 3.4Å; A289-D293 PolarHBondContact O-N 3.35Å; D293-Y296 PolarHBondContact O-N 3.42Å; D293-T297 VanDerWaalsContact O-CB 3.23Å; D293-T297 WeakPolarHBondContact O-CB 3.47Å; D293-T297 PolarHBondContact O-N 2.81Å; D293-T297 PolarHBondContact O-OG1 2.81Å; D293-T297 PolarHBondContact OD1-OG1 3.3Å
294Y88.4Confident83.8Confident133 Ų13345.1 Ų45.152%0.52224%0.242SC..Hα-helixtrans-62-51.3175.9174.1-100.7000112.5D290 Q291 Y296 T297 K298D290-Y294 WeakPolarHBondContact O-CB 3.45Å; D290-Y294 PolarHBondContact O-N 3.43Å; Q291-Y294 PolarHBondContact O-N 2.93Å; Y294-Y296 VanDerWaalsContact C-N 3.34Å; Y294-T297 PolarHBondContact O-N 3.38Å; Y294-K298 HydrophobicContact CE1-CD 4.4Å; Y294-K298 VanDerWaalsContact O-CB 3.3Å; Y294-K298 WeakPolarHBondContact O-CB 3.14Å; Y294-K298 PolarHBondContact O-N 2.92Å
295E86.4Confident81.4Confident27 Ų2747.3 Ų47.313%0.12625%0.253CS..Hα-helixtrans-69.3-34178.1-76.8-64.1135.700111.9L260 R263 L264 Q291 K298 M299L260-E295 HydrophobicContact CD1-CB 4.03Å; R263-E295 IonicContact CZ-OE2 2.89Å; R263-E295 IonicContact NE-OE2 3.67Å; R263-E295 PolarHBondContact NE-OE2 3.22Å; R263-E295 IonicContact NH2-OE2 2.94Å; L264-E295 HydrophobicContact CD2-CB 3.98Å; L264-E295 HydrophobicContact CD2-CG 3.98Å; L264-E295 HydrophobicContact CG-CB 4.43Å; Q291-E295 PolarHBondContact O-N 2.88Å; Q291-E295 VanDerWaalsContact O-N 3.13Å; E295-K298 PolarHBondContact O-N 3.16Å; E295-K298 IonicContact OE1-NZ 3.28Å; E295-K298 PolarHBondContact OE1-NZ 2.87Å; E295-K298 IonicContact OE2-NZ 3.81Å; E295-M299 WeakPolarHBondContact O-CG 3.14Å; E295-M299 PolarHBondContact O-N 3.18Å
296Y88.1Confident78.8Confident4 Ų447.8 Ų47.82%0.01626%0.263CS..Hα-helixtrans-57.6-55.7170.9171.6-96000111.6D136 V168 L260 L292 D293 Y294 K298 M299 Q300 F336 T338D136-Y296 PolarHBondContact OD1-OH 3.29Å; D136-Y296 PolarHBondContact OD2-OH 2.84Å; V168-Y296 HydrophobicContact CB-CD2 3.62Å; V168-Y296 HydrophobicContact CB-CE2 4.08Å; V168-Y296 HydrophobicContact CB-CG 4.01Å; V168-Y296 HydrophobicContact CG1-CD2 4.19Å; V168-Y296 HydrophobicContact CG1-CG 4.06Å; V168-Y296 HydrophobicContact CG2-CD2 4.4Å; L260-Y296 HydrophobicContact CD2-CD2 3.99Å; L292-Y296 WeakPolarHBondContact O-CB 3.28Å; L292-Y296 PolarHBondContact O-N 3.25Å; D293-Y296 PolarHBondContact O-N 3.42Å; Y294-Y296 VanDerWaalsContact C-N 3.34Å; Y296-K298 VanDerWaalsContact C-N 3.27Å; Y296-K298 PolarHBondContact O-N 3.5Å; Y296-M299 WeakPolarHBondContact O-CA 3.45Å; Y296-M299 WeakPolarHBondContact O-CB 3.32Å; Y296-M299 PolarHBondContact O-N 3.07Å; Y296-Q300 HydrophobicContact CD1-CG 4.36Å; Y296-Q300 HydrophobicContact CE1-CG 3.81Å; Y296-Q300 HydrophobicContact CE2-CG 4.35Å; Y296-Q300 WeakPolarHBondContact O-CG 3.31Å; Y296-Q300 PolarHBondContact O-N 2.62Å; Y296-Q300 PolarHBondContact OH-NE2 3.04Å; Y296-F336 HydrophobicContact CD2-CD1 4.21Å; Y296-F336 AromaticContact CD2-CE1 3.17Å; Y296-F336 HydrophobicContact CD2-CE1 3.17Å; Y296-F336 AromaticContact CD2-CZ 3.56Å; Y296-F336 HydrophobicContact CD2-CZ 3.56Å; Y296-F336 HydrophobicContact CE2-CD1 4Å; Y296-F336 AromaticContact CE2-CE1 3.13Å; Y296-F336 HydrophobicContact CE2-CE1 3.13Å; Y296-F336 HydrophobicContact CE2-CE2 4.21Å; Y296-F336 AromaticContact CE2-CZ 3.27Å; Y296-F336 HydrophobicContact CE2-CZ 3.27Å; Y296-F336 HydrophobicContact CG-CE1 4.15Å; Y296-T338 HydrophobicContact CE2-CG2 3.5Å; Y296-T338 VanDerWaalsContact CE2-CG2 3.5Å; Y296-T338 VanDerWaalsContact CZ-CG2 3.47Å; Y296-T338 WeakPolarHBondContact OH-CB 3.38Å; Y296-T338 WeakPolarHBondContact OH-CG2 3.5Å; Y296-T338 PolarHBondContact OH-OG1 3.47Å
297T84.3Confident76.1Confident16 Ų1651.7 Ų51.710%0.09826%0.26CS..Hα-helixtrans-60.1-37.4-180-66.60000111.7D293 Y294 M299 Q300 N301D293-T297 VanDerWaalsContact O-CB 3.23Å; D293-T297 WeakPolarHBondContact O-CB 3.47Å; D293-T297 PolarHBondContact O-N 2.81Å; D293-T297 PolarHBondContact O-OG1 2.81Å; D293-T297 PolarHBondContact OD1-OG1 3.3Å; Y294-T297 PolarHBondContact O-N 3.38Å; T297-M299 VanDerWaalsContact C-N 3.33Å; T297-M299 PolarHBondContact O-N 2.9Å; T297-Q300 PolarHBondContact O-N 3.23Å; T297-N301 WeakPolarHBondContact O-CB 3.27Å; T297-N301 PolarHBondContact O-N 3.03Å; T297-N301 PolarHBondContact O-ND2 2.91Å
298K81.3Confident73.5Confident54 Ų5455.9 Ų55.924%0.23529%0.286CS..Hα-helixtrans-65.3-34.8176.1-176.6180172.4-174.70112.6Y294 E295 Y296 M303 I304Y294-K298 HydrophobicContact CE1-CD 4.4Å; Y294-K298 VanDerWaalsContact O-CB 3.3Å; Y294-K298 WeakPolarHBondContact O-CB 3.14Å; Y294-K298 PolarHBondContact O-N 2.92Å; E295-K298 PolarHBondContact O-N 3.16Å; E295-K298 IonicContact OE1-NZ 3.28Å; E295-K298 PolarHBondContact OE1-NZ 2.87Å; E295-K298 IonicContact OE2-NZ 3.81Å; Y296-K298 VanDerWaalsContact C-N 3.27Å; Y296-K298 PolarHBondContact O-N 3.5Å; K298-M303 HydrophobicContact CG-CB 4.32Å; K298-M303 PolarHBondContact O-N 3.25Å; K298-I304 HydrophobicContact CG-CD1 4.14Å; K298-I304 HydrophobicContact CG-CG1 4.1Å
299M78.5Confident70.9Confident12 Ų1255 Ų556%0.05928%0.282CS..Hα-helixtrans-66.8-44.8170.2-75.2-174.758.700112.3P256 L259 L260 R263 E295 Y296 T297 N301 G302 I304 F336P256-M299 HydrophobicContact CB-CE 4.5Å; P256-M299 VanDerWaalsContact O-CE 3.3Å; P256-M299 WeakPolarHBondContact O-CE 3.21Å; L259-M299 HydrophobicContact CB-CE 3.83Å; L260-M299 VanDerWaalsContact CA-SD 3.6Å; L260-M299 HydrophobicContact CB-CE 4.45Å; L260-M299 HydrophobicContact CB-SD 3.77Å; L260-M299 HydrophobicContact CD1-SD 3.87Å; L260-M299 HydrophobicContact CG-SD 4.43Å; R263-M299 VanDerWaalsContact CD-SD 3.54Å; E295-M299 WeakPolarHBondContact O-CG 3.14Å; E295-M299 PolarHBondContact O-N 3.18Å; Y296-M299 WeakPolarHBondContact O-CA 3.45Å; Y296-M299 WeakPolarHBondContact O-CB 3.32Å; Y296-M299 PolarHBondContact O-N 3.07Å; T297-M299 VanDerWaalsContact C-N 3.33Å; T297-M299 PolarHBondContact O-N 2.9Å; M299-N301 VanDerWaalsContact C-N 3.35Å; M299-N301 PolarHBondContact O-N 3.25Å; M299-G302 PolarHBondContact O-N 3.46Å; M299-I304 HydrophobicContact CB-CD1 4.17Å; M299-I304 HydrophobicContact CG-CD1 3.39Å; M299-F336 HydrophobicContact CB-CB 4.49Å; M299-F336 HydrophobicContact CB-CD1 3.52Å; M299-F336 HydrophobicContact CB-CE1 4.04Å; M299-F336 HydrophobicContact CB-CG 4.37Å; M299-F336 HydrophobicContact CE-CD1 4.34Å; M299-F336 HydrophobicContact CE-CE1 4.44Å
300Q77.3Confident68.5Low19 Ų1960 Ų609%0.08930%0.299CS..Hα-helixtrans-60.6-42.6177.5-62-164.7-66.200112.9D136 Y296 T297 G302 F336D136-Q300 PolarHBondContact OD2-NE2 3.22Å; Y296-Q300 HydrophobicContact CD1-CG 4.36Å; Y296-Q300 HydrophobicContact CE1-CG 3.81Å; Y296-Q300 HydrophobicContact CE2-CG 4.35Å; Y296-Q300 WeakPolarHBondContact O-CG 3.31Å; Y296-Q300 PolarHBondContact O-N 2.62Å; Y296-Q300 PolarHBondContact OH-NE2 3.04Å; T297-Q300 PolarHBondContact O-N 3.23Å; Q300-G302 PolarHBondContact O-N 2.85Å; Q300-G302 VanDerWaalsContact O-N 3.15Å; Q300-F336 HydrophobicContact CG-CD1 3.67Å; Q300-F336 HydrophobicContact CG-CE1 4.34Å; Q300-F336 HydrophobicContact CG-CG 4.3Å; Q300-F336 WeakPolarHBondContact CG-O 3.49Å
301N71.1Confident66.2Low75 Ų7564.6 Ų64.640%0.40132%0.315SS..THydrogen-bonded Turntrans-74.31.3-178.1-68.8-25.2000113.8R94 T297 M299 M303R94-N301 PolarHBondContact NH2-OD1 3.48Å; T297-N301 WeakPolarHBondContact O-CB 3.27Å; T297-N301 PolarHBondContact O-N 3.03Å; T297-N301 PolarHBondContact O-ND2 2.91Å; M299-N301 VanDerWaalsContact C-N 3.35Å; M299-N301 PolarHBondContact O-N 3.25Å; N301-M303 HydrophobicContact CB-CG 3.94Å; N301-M303 HydrophobicContact CB-SD 4.22Å; N301-M303 PolarHBondContact O-N 2.83Å
302G62.6Low63.6Low29 Ų2968.8 Ų68.830%0.29933%0.331SS..THydrogen-bonded Turntrans64.47.1-179.700000114.7M299 Q300 I304 L305M299-G302 PolarHBondContact O-N 3.46Å; Q300-G302 PolarHBondContact O-N 2.85Å; Q300-G302 VanDerWaalsContact O-N 3.15Å; G302-I304 PolarHBondContact O-N 2.9Å; G302-L305 WeakPolarHBondContact O-CB 3.34Å; G302-L305 PolarHBondContact O-N 3.36Å
303M48.5Very low61.1Low127 Ų12771.3 Ų71.363%0.62635%0.352SS*.THydrogen-bonded Turntrans-61.4-13-174.8-71.4179.570.500113.6K298 N301K298-M303 HydrophobicContact CG-CB 4.32Å; K298-M303 PolarHBondContact O-N 3.25Å; N301-M303 HydrophobicContact CB-CG 3.94Å; N301-M303 HydrophobicContact CB-SD 4.22Å; N301-M303 PolarHBondContact O-N 2.83Å
304I49.8Very low58.6Low34 Ų3482 Ų8217%0.17439%0.392CS..THydrogen-bonded Turntrans-79.7-24.6178.3-68.7153.7000112.1R263 K298 M299 G302 S306 S309R263-I304 VanDerWaalsContact CZ-CG1 3.46Å; R263-I304 VanDerWaalsContact NH1-CG1 3.35Å; K298-I304 HydrophobicContact CG-CD1 4.14Å; K298-I304 HydrophobicContact CG-CG1 4.1Å; M299-I304 HydrophobicContact CB-CD1 4.17Å; M299-I304 HydrophobicContact CG-CD1 3.39Å; G302-I304 PolarHBondContact O-N 2.9Å; I304-S306 PolarHBondContact O-N 3.26Å; I304-S309 WeakPolarHBondContact O-CB 3.48Å
305L44.7Very low56.6Low47 Ų4779.3 Ų79.325%0.24639%0.386CS..  trans-78.6-6.4-173.1-61.7166.3000113.4G302 R307 I328 S332G302-L305 WeakPolarHBondContact O-CB 3.34Å; G302-L305 PolarHBondContact O-N 3.36Å; L305-R307 PolarHBondContact O-N 2.77Å; L305-I328 HydrophobicContact CD2-CG2 3.31Å; L305-S332 VanDerWaalsContact CD1-CA 3.44Å
306S41.5Very low54.5Low51 Ų5186.4 Ų86.436%0.35742%0.419SS..SBendtrans-57.3126.4170.881.80000108.8I304 T308 S309I304-S306 PolarHBondContact O-N 3.26Å; S306-T308 WeakPolarHBondContact CB-OG1 3.36Å; S306-T308 PolarHBondContact O-N 2.56Å; S306-T308 PolarHBondContact OG-OG1 2.74Å; S306-S309 WeakPolarHBondContact O-CB 3.47Å; S306-S309 PolarHBondContact O-N 3.5Å; S306-S309 PolarHBondContact OG-OG 2.89Å; S306-S309 VanDerWaalsContact OG-OG 3.12Å
307R40.1Very low52.6Low164 Ų16492 Ų9262%0.61944%0.444SS*.Hα-helixtrans-50.4-27.5179.1-96178.8153.5136-4.7112.8L305 R310L305-R307 PolarHBondContact O-N 2.77Å; R307-R310 PolarHBondContact O-N 2.73Å
308T40.6Very low50.8Low102 Ų10296.3 Ų96.363%0.62647%0.472SS*.Hα-helixtrans-65-37.2174.9330000113.4S306 K311 K312S306-T308 WeakPolarHBondContact CB-OG1 3.36Å; S306-T308 PolarHBondContact O-N 2.56Å; S306-T308 PolarHBondContact OG-OG1 2.74Å; T308-K311 PolarHBondContact O-N 2.89Å; T308-K312 PolarHBondContact O-N 2.9Å
309S42.6Very low49.1Very low48 Ų48101.7 Ų101.734%0.33650%0.498SS..Hα-helixtrans-70.4-32177.1-61.40000112.3I304 S306 K311 K312 A313I304-S309 WeakPolarHBondContact O-CB 3.48Å; S306-S309 WeakPolarHBondContact O-CB 3.47Å; S306-S309 PolarHBondContact O-N 3.5Å; S306-S309 PolarHBondContact OG-OG 2.89Å; S306-S309 VanDerWaalsContact OG-OG 3.12Å; S309-K311 VanDerWaalsContact C-N 3.34Å; S309-K311 PolarHBondContact O-N 3.17Å; S309-K312 PolarHBondContact O-N 2.96Å; S309-A313 PolarHBondContact O-N 3.27Å; S309-A313 VanDerWaalsContact O-N 3.13Å
310R43.8Very low47.8Very low111 Ų111103.9 Ų103.942%0.41951%0.507SS..Hα-helixtrans-60.3-40.4173.6-78.7-174.9-103.5-169.4-8.6112.5R307R307-R310 PolarHBondContact O-N 2.73Å
311K42.7Very low46.3Very low199 Ų199106.8 Ų106.887%0.86552%0.521SS*.Hα-helixtrans-73.9-24.1178.1-77.6-169.1173.8-170.30114.2T308 S309T308-K311 PolarHBondContact O-N 2.89Å; S309-K311 VanDerWaalsContact C-N 3.34Å; S309-K311 PolarHBondContact O-N 3.17Å
312K39.7Very low45.1Very low182 Ų182109.7 Ų109.779%0.79154%0.536SS*.Hα-helixtrans-93.7-15.3-177.9-87.1-171.6175.2-176.50113.9T308 S309 W314T308-K312 PolarHBondContact O-N 2.9Å; S309-K312 PolarHBondContact O-N 2.96Å; K312-W314 PolarHBondContact O-N 2.94Å; K312-W314 VanDerWaalsContact O-N 3.16Å
313A40.7Very low44.3Very low54 Ų54112.6 Ų112.645%0.44654%0.544SS..  trans-72.4109.917400000108.9S309 L315S309-A313 PolarHBondContact O-N 3.27Å; S309-A313 VanDerWaalsContact O-N 3.13Å; A313-L315 HydrophobicContact CB-CD1 4.21Å; A313-L315 HydrophobicContact CB-CG 4.48Å; A313-L315 PolarHBondContact O-N 3.37Å
314W37.8Very low44.2Very low233 Ų233108.8 Ų108.888%0.88353%0.526SS*.  trans-61.729.7176.9-99.874.1000114.8K312 H316K312-W314 PolarHBondContact O-N 2.94Å; K312-W314 VanDerWaalsContact O-N 3.16Å; W314-H316 PolarHBondContact O-N 3.48Å
315L46.5Very low44.1Very low77 Ų77110 Ų11040%0.40353%0.533SS..  trans-99.867.8-171.4-65.8169.3000110.2Y262 A313 K317Y262-L315 HydrophobicContact CE1-CD1 3.65Å; Y262-L315 HydrophobicContact CE1-CD2 3.93Å; Y262-L315 HydrophobicContact CE1-CG 4.42Å; Y262-L315 VanDerWaalsContact OH-CD2 3.29Å; Y262-L315 WeakPolarHBondContact OH-CD2 3.21Å; A313-L315 HydrophobicContact CB-CD1 4.21Å; A313-L315 HydrophobicContact CB-CG 4.48Å; A313-L315 PolarHBondContact O-N 3.37Å; L315-K317 PolarHBondContact O-N 3.26Å
316H42.6Very low44.3Very low176 Ų176111.2 Ų111.282%0.81555%0.545SS*.  trans-72.249.6176.4-78.8-69.4000113.5W314W314-H316 PolarHBondContact O-N 3.48Å
317K47.5Very low44.5Very low122 Ų122110.9 Ų110.953%0.5354%0.539SS..  trans-114.6105.5166.6-75-160.7175.4-172.60110.6L315 E319 F320 E321L315-K317 PolarHBondContact O-N 3.26Å; K317-E319 VanDerWaalsContact C-N 3.28Å; K317-E319 PolarHBondContact O-N 2.99Å; K317-F320 HydrophobicContact CB-CB 4.25Å; K317-F320 HydrophobicContact CB-CD2 3.97Å; K317-F320 HydrophobicContact CD-CD2 4.14Å; K317-F320 HydrophobicContact CD-CE2 4.44Å; K317-F320 PolarHBondContact O-N 3.38Å; K317-E321 PolarHBondContact O-N 3.25Å
318P46.6Very low44.7Very low107 Ų107104.3 Ų104.370%0.69552%0.516SS*.Hα-helixtrans-62.3-32.2-175.820.5-29.5000113.4F320 E321 L322P318-F320 PolarHBondContact O-N 3.12Å; P318-E321 PolarHBondContact O-N 2.96Å; P318-L322 PolarHBondContact O-N 3.31Å
319E46.4Very low44.7Very low166 Ų166105 Ų10578%0.77652%0.515SS*.Hα-helixtrans-60-31.8173.4-66.9178.9171.500112.4K317K317-E319 VanDerWaalsContact C-N 3.28Å; K317-E319 PolarHBondContact O-N 2.99Å
320F50Low44.5Very low59 Ų59105.2 Ų105.226%0.25952%0.515SS..Hα-helixtrans-87.7-31-178.8-83.8-85.7000113.4Y262 L269 K317 P318 L322 L323 L324Y262-F320 HydrophobicContact CE2-CD1 4.3Å; Y262-F320 HydrophobicContact CE2-CE1 4.36Å; L269-F320 HydrophobicContact CD1-CE2 3.98Å; L269-F320 HydrophobicContact CD1-CZ 3.68Å; K317-F320 HydrophobicContact CB-CB 4.25Å; K317-F320 HydrophobicContact CB-CD2 3.97Å; K317-F320 HydrophobicContact CD-CD2 4.14Å; K317-F320 HydrophobicContact CD-CE2 4.44Å; K317-F320 PolarHBondContact O-N 3.38Å; P318-F320 PolarHBondContact O-N 3.12Å; F320-L322 PolarHBondContact O-N 3.34Å; F320-L323 PolarHBondContact O-N 3.01Å; F320-L324 WeakPolarHBondContact O-CB 2.97Å; F320-L324 PolarHBondContact O-N 3.28Å
321E46.4Very low44.6Very low79 Ų79101.1 Ų101.137%0.36950%0.502SS..Hα-helixtrans-56.2-37.1169.8-94.4-82.5158.900110.9K317 P318 N325K317-E321 PolarHBondContact O-N 3.25Å; P318-E321 PolarHBondContact O-N 2.96Å; E321-N325 VanDerWaalsContact O-CB 3.22Å; E321-N325 WeakPolarHBondContact O-CB 3.33Å; E321-N325 PolarHBondContact O-N 3.48Å; E321-N325 PolarHBondContact O-ND2 2.8Å; E321-N325 PolarHBondContact OE2-ND2 3.41Å
322L45.8Very low44.7Very low137 Ų13794.3 Ų94.372%0.71748%0.479SS*.Hα-helixtrans-65-46.8176.5-157.187.6000111.8P318 F320 N325 S326P318-L322 PolarHBondContact O-N 3.31Å; F320-L322 PolarHBondContact O-N 3.34Å; L322-N325 PolarHBondContact O-N 3.47Å; L322-S326 PolarHBondContact O-N 2.92Å; L322-S326 PolarHBondContact O-OG 3.31Å
323L45.8Very low44.9Very low90 Ų9090.9 Ų90.947%0.47147%0.466SS..Hα-helixtrans-64.8-43.3177.4-158.194.9000111.1F320 S326 L327F320-L323 PolarHBondContact O-N 3.01Å; L323-S326 PolarHBondContact O-N 3.46Å; L323-S326 PolarHBondContact O-OG 3.39Å; L323-L327 HydrophobicContact CD2-CD1 3.69Å; L323-L327 HydrophobicContact CG-CD1 3.69Å; L323-L327 HydrophobicContact CG-CG 4.38Å; L323-L327 VanDerWaalsContact O-CB 3.28Å; L323-L327 WeakPolarHBondContact O-CB 3.18Å; L323-L327 WeakPolarHBondContact O-CD1 3.33Å; L323-L327 WeakPolarHBondContact O-CG 3.48Å; L323-L327 PolarHBondContact O-N 2.79Å
324L47.3Very low45.4Very low47 Ų4790.7 Ų90.725%0.24646%0.455CS..Hα-helixtrans-60.8-49.4175.7-132.283.5000109.3L259 F320 S326 L327 I328L259-L324 HydrophobicContact CD2-CD1 3.73Å; F320-L324 WeakPolarHBondContact O-CB 2.97Å; F320-L324 PolarHBondContact O-N 3.28Å; L324-S326 VanDerWaalsContact C-N 3.34Å; L324-S326 PolarHBondContact O-N 2.98Å; L324-L327 PolarHBondContact O-N 3.44Å; L324-I328 HydrophobicContact CB-CD1 3.88Å; L324-I328 HydrophobicContact CD2-CD1 3.6Å; L324-I328 HydrophobicContact CG-CD1 3.58Å; L324-I328 HydrophobicContact CG-CG1 4.26Å; L324-I328 WeakPolarHBondContact O-CA 3.22Å; L324-I328 WeakPolarHBondContact O-CB 3.34Å; L324-I328 VanDerWaalsContact O-CD1 3.23Å; L324-I328 WeakPolarHBondContact O-CD1 3.44Å; L324-I328 WeakPolarHBondContact O-CG1 3.43Å; L324-I328 PolarHBondContact O-N 2.86Å
325N47.5Very low46.2Very low60 Ų6080.7 Ų80.732%0.32142%0.424SS..Hα-helixtrans-65.5-34.2-178.1-73.8-47.9000112.8E321 L322E321-N325 VanDerWaalsContact O-CB 3.22Å; E321-N325 WeakPolarHBondContact O-CB 3.33Å; E321-N325 PolarHBondContact O-N 3.48Å; E321-N325 PolarHBondContact O-ND2 2.8Å; E321-N325 PolarHBondContact OE2-ND2 3.41Å; L322-N325 PolarHBondContact O-N 3.47Å
326S47.8Very low47.1Very low71 Ų7177.1 Ų77.150%0.49741%0.405SS..Hα-helixtrans-72.4-38.2175.365.20000112.8L322 L323 L324 P330L322-S326 PolarHBondContact O-N 2.92Å; L322-S326 PolarHBondContact O-OG 3.31Å; L323-S326 PolarHBondContact O-N 3.46Å; L323-S326 PolarHBondContact O-OG 3.39Å; L324-S326 VanDerWaalsContact C-N 3.34Å; L324-S326 PolarHBondContact O-N 2.98Å; S326-P330 WeakPolarHBondContact O-CD 3.14Å
327L45.3Very low48.3Very low44 Ų4470.8 Ų70.823%0.2338%0.375CS..Hα-helixtrans-80.2-28.3178.5-62.4169.1000112.8T255 L259 L323 L324 P330 I331T255-L327 HydrophobicContact CG2-CB 3.8Å; T255-L327 HydrophobicContact CG2-CD1 3.92Å; T255-L327 HydrophobicContact CG2-CD2 3.56Å; T255-L327 HydrophobicContact CG2-CG 3.93Å; L259-L327 HydrophobicContact CD1-CB 4.48Å; L323-L327 HydrophobicContact CD2-CD1 3.69Å; L323-L327 HydrophobicContact CG-CD1 3.69Å; L323-L327 HydrophobicContact CG-CG 4.38Å; L323-L327 VanDerWaalsContact O-CB 3.28Å; L323-L327 WeakPolarHBondContact O-CB 3.18Å; L323-L327 WeakPolarHBondContact O-CD1 3.33Å; L323-L327 WeakPolarHBondContact O-CG 3.48Å; L323-L327 PolarHBondContact O-N 2.79Å; L324-L327 PolarHBondContact O-N 3.44Å; L327-P330 VanDerWaalsContact O-CD 3.31Å; L327-P330 WeakPolarHBondContact O-CD 3.43Å; L327-I331 WeakPolarHBondContact O-CD1 3.47Å; L327-I331 WeakPolarHBondContact O-CG1 3.17Å
328I45.4Very low49.8Very low26 Ų2665.2 Ų65.213%0.13335%0.351CS..Hα-helixtrans-69.1-39.1-177.7-82.3165.2000111.8L305 L324 I331 S332L305-I328 HydrophobicContact CD2-CG2 3.31Å; L324-I328 HydrophobicContact CB-CD1 3.88Å; L324-I328 HydrophobicContact CD2-CD1 3.6Å; L324-I328 HydrophobicContact CG-CD1 3.58Å; L324-I328 HydrophobicContact CG-CG1 4.26Å; L324-I328 WeakPolarHBondContact O-CA 3.22Å; L324-I328 WeakPolarHBondContact O-CB 3.34Å; L324-I328 VanDerWaalsContact O-CD1 3.23Å; L324-I328 WeakPolarHBondContact O-CD1 3.44Å; L324-I328 WeakPolarHBondContact O-CG1 3.43Å; L324-I328 PolarHBondContact O-N 2.86Å; I328-I331 PolarHBondContact O-N 3.13Å; I328-I331 VanDerWaalsContact O-N 3.09Å; I328-S332 WeakPolarHBondContact O-CB 3.31Å; I328-S332 PolarHBondContact O-N 3.12Å; I328-S332 PolarHBondContact O-OG 3.41Å
329L39.3Very low51.8Low117 Ų11760.4 Ų60.461%0.61332%0.32SS*.Hα-helixtrans-54.9-50.9-177-75.5171.8000112I331 S332 E333L329-I331 PolarHBondContact O-N 3.45Å; L329-S332 PolarHBondContact O-N 3.08Å; L329-S332 PolarHBondContact O-OG 3.29Å; L329-E333 PolarHBondContact O-N 3.41Å
330P40Very low54Low53 Ų5352.5 Ų52.534%0.34428%0.283SS..Hα-helixtrans-56.7-48.6172.3-8.88.3000112.4S326 L327 S332 E333 F334S326-P330 WeakPolarHBondContact O-CD 3.14Å; L327-P330 VanDerWaalsContact O-CD 3.31Å; L327-P330 WeakPolarHBondContact O-CD 3.43Å; P330-S332 PolarHBondContact O-N 2.82Å; P330-E333 PolarHBondContact O-N 3.16Å; P330-F334 HydrophobicContact CB-CD2 4.21Å; P330-F334 WeakPolarHBondContact O-CB 3.5Å; P330-F334 WeakPolarHBondContact O-CD2 3.42Å; P330-F334 PolarHBondContact O-N 2.89Å
331I45.2Very low55.9Low25 Ų2551.5 Ų51.513%0.12828%0.278CS..Hα-helixtrans-62.1-34.6-175.9-60.7166.8000111.5T255 L259 L327 I328 L329 G335 F336T255-I331 HydrophobicContact CG2-CD1 4.32Å; L259-I331 HydrophobicContact CD1-CD1 3.16Å; L327-I331 WeakPolarHBondContact O-CD1 3.47Å; L327-I331 WeakPolarHBondContact O-CG1 3.17Å; I328-I331 PolarHBondContact O-N 3.13Å; I328-I331 VanDerWaalsContact O-N 3.09Å; L329-I331 PolarHBondContact O-N 3.45Å; I331-G335 VanDerWaalsContact O-CA 3.27Å; I331-G335 WeakPolarHBondContact O-CA 3.26Å; I331-G335 PolarHBondContact O-N 3.47Å; I331-F336 HydrophobicContact CG2-CB 4.43Å
332S44.3Very low58Low56 Ų5649.2 Ų49.239%0.39227%0.268SS..Hα-helixtrans-69-38.4178.271.40000114L305 I328 L329 P330L305-S332 VanDerWaalsContact CD1-CA 3.44Å; I328-S332 WeakPolarHBondContact O-CB 3.31Å; I328-S332 PolarHBondContact O-N 3.12Å; I328-S332 PolarHBondContact O-OG 3.41Å; L329-S332 PolarHBondContact O-N 3.08Å; L329-S332 PolarHBondContact O-OG 3.29Å; P330-S332 PolarHBondContact O-N 2.82Å
333E44Very low60.1Low110 Ų11043.9 Ų43.951%0.51424%0.24SC..Hα-helixtrans-80.3-36.7179.3-70.4-167.6167.800111.9L329 P330 K400L329-E333 PolarHBondContact O-N 3.41Å; P330-E333 PolarHBondContact O-N 3.16Å; E333-K400 PolarHBondContact O-NZ 3.24Å
334F51.1Low62.1Low50 Ų5040.3 Ų40.322%0.21923%0.225CC..Hα-helixtrans-85.3-45.5-175.6-66.8-64000111.9R248 P330 F337 K400 V403 I404R248-F334 PolarHBondContact NH2-O 2.85Å; P330-F334 HydrophobicContact CB-CD2 4.21Å; P330-F334 WeakPolarHBondContact O-CB 3.5Å; P330-F334 WeakPolarHBondContact O-CD2 3.42Å; P330-F334 PolarHBondContact O-N 2.89Å; F334-F337 WeakPolarHBondContact O-CE2 3.4Å; F334-K400 HydrophobicContact CE1-CG 4.48Å; F334-V403 HydrophobicContact CE1-CB 4.41Å; F334-V403 HydrophobicContact CE1-CG1 4.25Å; F334-V403 HydrophobicContact CE2-CG1 4.12Å; F334-V403 HydrophobicContact CZ-CB 3.92Å; F334-V403 HydrophobicContact CZ-CG1 3.39Å; F334-I404 HydrophobicContact CD1-CD1 4.48Å; F334-I404 HydrophobicContact CD1-CG1 3.87Å; F334-I404 HydrophobicContact CE1-CD1 4.48Å; F334-I404 HydrophobicContact CE1-CG1 3.65Å
335G55.5Low63.9Low22 Ų2242 Ų4223%0.22725%0.246CC..  trans89.6149.3-159.900000110.5I331 F337I331-G335 VanDerWaalsContact O-CA 3.27Å; I331-G335 WeakPolarHBondContact O-CA 3.26Å; I331-G335 PolarHBondContact O-N 3.47Å; G335-F337 VanDerWaalsContact O-CD2 3.24Å; G335-F337 WeakPolarHBondContact O-CD2 3.42Å; G335-F337 WeakPolarHBondContact O-CE2 3.19Å
336F64.2Low65.8Low3 Ų346 Ų461%0.01327%0.267CS..  trans-79.5121170.3170.5-137.8000109.4P256 Y257 Y296 M299 Q300 I331P256-F336 HydrophobicContact CB-CD2 3.06Å; P256-F336 HydrophobicContact CB-CE2 3.13Å; P256-F336 HydrophobicContact CB-CG 3.94Å; P256-F336 HydrophobicContact CB-CZ 3.98Å; P256-F336 HydrophobicContact CG-CD2 3.78Å; P256-F336 HydrophobicContact CG-CE2 4.12Å; Y257-F336 HydrophobicContact CD1-CE2 4.26Å; Y257-F336 AromaticContact CD1-CZ 3.97Å; Y257-F336 HydrophobicContact CD1-CZ 3.97Å; Y257-F336 HydrophobicContact CE1-CE2 4.02Å; Y257-F336 AromaticContact CE1-CZ 3.84Å; Y257-F336 HydrophobicContact CE1-CZ 3.84Å; Y296-F336 HydrophobicContact CD2-CD1 4.21Å; Y296-F336 AromaticContact CD2-CE1 3.17Å; Y296-F336 HydrophobicContact CD2-CE1 3.17Å; Y296-F336 AromaticContact CD2-CZ 3.56Å; Y296-F336 HydrophobicContact CD2-CZ 3.56Å; Y296-F336 HydrophobicContact CE2-CD1 4Å; Y296-F336 AromaticContact CE2-CE1 3.13Å; Y296-F336 HydrophobicContact CE2-CE1 3.13Å; Y296-F336 HydrophobicContact CE2-CE2 4.21Å; Y296-F336 AromaticContact CE2-CZ 3.27Å; Y296-F336 HydrophobicContact CE2-CZ 3.27Å; Y296-F336 HydrophobicContact CG-CE1 4.15Å; M299-F336 HydrophobicContact CB-CB 4.49Å; M299-F336 HydrophobicContact CB-CD1 3.52Å; M299-F336 HydrophobicContact CB-CE1 4.04Å; M299-F336 HydrophobicContact CB-CG 4.37Å; M299-F336 HydrophobicContact CE-CD1 4.34Å; M299-F336 HydrophobicContact CE-CE1 4.44Å; Q300-F336 HydrophobicContact CG-CD1 3.67Å; Q300-F336 HydrophobicContact CG-CE1 4.34Å; Q300-F336 HydrophobicContact CG-CG 4.3Å; Q300-F336 WeakPolarHBondContact CG-O 3.49Å; I331-F336 HydrophobicContact CG2-CB 4.43Å
337F69.8Low67.9Low43 Ų4343.2 Ų43.219%0.18925%0.25CS..  trans-126.3146.6175.2-62.3-86.8000109.8R248 M251 F334 G335R248-F337 VanDerWaalsContact CZ-CE2 3.41Å; R248-F337 VanDerWaalsContact CZ-CZ 3.44Å; R248-F337 VanDerWaalsContact NH2-CE2 3.31Å; M251-F337 HydrophobicContact CE-CB 4.37Å; F334-F337 WeakPolarHBondContact O-CE2 3.4Å; G335-F337 VanDerWaalsContact O-CD2 3.24Å; G335-F337 WeakPolarHBondContact O-CD2 3.42Å; G335-F337 WeakPolarHBondContact O-CE2 3.19Å
338T79Confident70.3Confident4 Ų441.5 Ų41.53%0.02524%0.241CC..  trans-88.5140.5164.539.30000109.2D136 G167 F171 Y257 Y296D136-T338 PolarHBondContact OD1-OG1 2.61Å; D136-T338 PolarHBondContact OD2-OG1 2.84Å; G167-T338 VanDerWaalsContact C-CG2 3.44Å; F171-T338 HydrophobicContact CB-CG2 4.34Å; Y257-T338 HydrophobicContact CE1-CG2 4.21Å; Y257-T338 VanDerWaalsContact OH-CG2 3.28Å; Y257-T338 WeakPolarHBondContact OH-CG2 3.09Å; Y296-T338 HydrophobicContact CE2-CG2 3.5Å; Y296-T338 VanDerWaalsContact CE2-CG2 3.5Å; Y296-T338 VanDerWaalsContact CZ-CG2 3.47Å; Y296-T338 WeakPolarHBondContact OH-CB 3.38Å; Y296-T338 WeakPolarHBondContact OH-CG2 3.5Å; Y296-T338 PolarHBondContact OH-OG1 3.47Å
339S86.8Confident72.6Confident6 Ų640.2 Ų40.24%0.04223%0.234CC..  trans-160163.7170.960.30000107.6R248 F250 M251R248-S339 WeakPolarHBondContact O-CB 3.35Å; F250-S339 VanDerWaalsContact C-OG 3.26Å; M251-S339 WeakPolarHBondContact CB-OG 3.4Å; M251-S339 PolarHBondContact N-OG 2.88Å
340P94Very high75.1Confident0 Ų036.1 Ų36.10%021%0.214CC..  trans-45.6160.5159.5-29.434.3000113.4F135 F171 N182 L185 L223 A249 F250 M251 L349F135-P340 HydrophobicContact CE1-CG 3.97Å; F135-P340 HydrophobicContact CE2-CG 4.31Å; F135-P340 HydrophobicContact CZ-CG 3.83Å; F171-P340 HydrophobicContact CD1-CG 4.48Å; F171-P340 HydrophobicContact CE1-CB 4.39Å; F171-P340 HydrophobicContact CE1-CG 3.79Å; F171-P340 HydrophobicContact CZ-CG 4.44Å; N182-P340 WeakPolarHBondContact OD1-CA 3.32Å; L185-P340 HydrophobicContact CD1-CB 3.73Å; L185-P340 HydrophobicContact CD1-CG 3.78Å; L185-P340 HydrophobicContact CD2-CG 4.19Å; L185-P340 HydrophobicContact CG-CB 4.4Å; L185-P340 HydrophobicContact CG-CG 4.02Å; L223-P340 HydrophobicContact CD1-CB 3.94Å; L223-P340 HydrophobicContact CD1-CG 3.78Å; A249-P340 VanDerWaalsContact O-CD 3.31Å; A249-P340 WeakPolarHBondContact O-CD 3.15Å; F250-P340 CarbonylContact C-O 3.5Å; F250-P340 WeakPolarHBondContact CA-O 3.1Å; F250-P340 HydrophobicContact CB-CB 4.4Å; F250-P340 WeakPolarHBondContact CB-O 3.36Å; M251-P340 PolarHBondContact N-O 2.71Å; P340-L349 HydrophobicContact CB-CD1 4.01Å
341R90.1Very high77.5Confident39 Ų3937.2 Ų37.215%0.14722%0.217CC..  trans-135.6161.3175.366172.1-72.3-94.9-5.2111.2S173 E180 N182 M251 D343S173-R341 WeakPolarHBondContact OG-CD 3.09Å; E180-R341 WeakPolarHBondContact O-CD 3.45Å; E180-R341 PolarHBondContact O-NH1 2.79Å; N182-R341 PolarHBondContact ND2-O 2.94Å; N182-R341 PolarHBondContact OD1-N 3.3Å; M251-R341 WeakPolarHBondContact O-CB 3.3Å; R341-D343 PolarHBondContact O-N 2.91Å
342I89.6Confident79.5Confident30 Ų3038.1 Ų38.115%0.15422%0.222CC..  trans-68.3121.1163.2-60.5174.5000107.8F250 N252 L349 D352F250-I342 HydrophobicContact CD2-CG1 4.33Å; F250-I342 HydrophobicContact CE2-CD1 4.35Å; F250-I342 HydrophobicContact CE2-CG1 4.42Å; N252-I342 WeakPolarHBondContact ND2-CD1 3.18Å; N252-I342 VanDerWaalsContact OD1-CB 3.31Å; N252-I342 WeakPolarHBondContact OD1-CB 3.23Å; N252-I342 WeakPolarHBondContact OD1-CG1 3.3Å; N252-I342 PolarHBondContact OD1-N 2.83Å; I342-L349 WeakPolarHBondContact CA-O 3.36Å; I342-L349 WeakPolarHBondContact CG2-O 3.04Å; I342-D352 VanDerWaalsContact CD1-CA 3.45Å; I342-D352 HydrophobicContact CD1-CB 3.96Å
343D90.4Very high81.6Confident25 Ų2535.4 Ų35.413%0.13420%0.203CC..  trans-112.25.6-174.855.7-0.3000113.9N182 R341 G347 I348 L349N182-D343 PolarHBondContact ND2-OD2 3.39Å; R341-D343 PolarHBondContact O-N 2.91Å; D343-G347 WeakPolarHBondContact OD1-CA 3.49Å; D343-I348 VanDerWaalsContact CG-N 3.29Å; D343-I348 PolarHBondContact OD1-N 2.76Å; D343-I348 PolarHBondContact OD2-N 3.44Å; D343-L349 PolarHBondContact N-O 2.75Å; D343-L349 VanDerWaalsContact OD1-C 3.24Å; D343-L349 WeakPolarHBondContact OD1-CA 3.18Å; D343-L349 PolarHBondContact OD1-N 2.91Å
344G86.7Confident83.6Confident16 Ų1632.4 Ų32.417%0.16519%0.19CC..  trans93.7173167.900000113.8D346 G347 P350G344-D346 PolarHBondContact O-N 3.39Å; G344-G347 WeakPolarHBondContact O-CA 3.38Å; G344-G347 PolarHBondContact O-N 3.27Å; G344-P350 CarbonylContact C-O 3.59Å; G344-P350 WeakPolarHBondContact O-CA 3.19Å; G344-P350 WeakPolarHBondContact O-CB 3.27Å
345A85.6Confident85.3Confident82 Ų8233.7 Ų33.768%0.67820%0.198SC*.THydrogen-bonded Turntrans-49.3-34.2-16200000116.3
346D87.5Confident86.9Confident144 Ų14434.1 Ų34.177%0.7720%0.195SC*.THydrogen-bonded Turntrans-98.11-179.4-62.9-45.9000114K229 G344K229-D346 WeakPolarHBondContact CE-O 3.37Å; K229-D346 PolarHBondContact NZ-O 2.89Å; G344-D346 PolarHBondContact O-N 3.39Å
347G92.2Very high88.2Confident13 Ų1334.4 Ų34.413%0.13420%0.197CC..SBendtrans-83.5-168.2-176.900000114.4K229 D343 G344K229-G347 WeakPolarHBondContact CE-O 3.43Å; D343-G347 WeakPolarHBondContact OD1-CA 3.49Å; G344-G347 WeakPolarHBondContact O-CA 3.38Å; G344-G347 PolarHBondContact O-N 3.27Å
348I95.6Very high88.9Confident7 Ų737.6 Ų37.64%0.03621%0.212CC..SBendtrans-76.1-40.7176.7-65.9165.7000110.5N182 L185 S186 I189 L224 S227 K229 D343 P350N182-I348 HydrophobicContact CB-CD1 4.08Å; L185-I348 HydrophobicContact CB-CD1 3.85Å; L185-I348 HydrophobicContact CB-CG2 4.37Å; L185-I348 HydrophobicContact CD1-CG2 4.08Å; S186-I348 WeakPolarHBondContact OG-CD1 3.4Å; I189-I348 HydrophobicContact CD1-CB 4.47Å; I189-I348 HydrophobicContact CD1-CD1 3.78Å; I189-I348 HydrophobicContact CD1-CG1 3.71Å; I189-I348 HydrophobicContact CD1-CG2 3.94Å; L224-I348 HydrophobicContact CD2-CG2 4.33Å; S227-I348 VanDerWaalsContact CB-O 3.23Å; S227-I348 WeakPolarHBondContact CB-O 3.33Å; S227-I348 PolarHBondContact OG-O 2.81Å; K229-I348 HydrophobicContact CG-CG1 4.35Å; D343-I348 VanDerWaalsContact CG-N 3.29Å; D343-I348 PolarHBondContact OD1-N 2.76Å; D343-I348 PolarHBondContact OD2-N 3.44Å; I348-P350 WeakPolarHBondContact O-CD 3.36Å
349L93.9Very high89.2Confident0 Ų044.8 Ų44.80%025%0.251CS..SBendtrans-119.786-179.8-64179.7000108.7L185 L223 P340 I342 D343 I351L185-L349 HydrophobicContact CD1-CD1 4.3Å; L223-L349 HydrophobicContact CB-CD2 4.23Å; L223-L349 HydrophobicContact CD1-CD1 4.34Å; L223-L349 HydrophobicContact CD2-CD1 3.91Å; L223-L349 HydrophobicContact CD2-CD2 4.01Å; P340-L349 HydrophobicContact CB-CD1 4.01Å; I342-L349 WeakPolarHBondContact CA-O 3.36Å; I342-L349 WeakPolarHBondContact CG2-O 3.04Å; D343-L349 PolarHBondContact N-O 2.75Å; D343-L349 VanDerWaalsContact OD1-C 3.24Å; D343-L349 WeakPolarHBondContact OD1-CA 3.18Å; D343-L349 PolarHBondContact OD1-N 2.91Å; L349-I351 VanDerWaalsContact C-N 3.31Å; L349-I351 PolarHBondContact O-N 2.9Å
350P91.8Very high89.5Confident30 Ų3045.1 Ų45.120%0.19525%0.251CS..  trans-71.5-26.4-168.125.6-34.6000114.7P228 G344 I348 L356P228-P350 HydrophobicContact CG-CG 4.43Å; G344-P350 CarbonylContact C-O 3.59Å; G344-P350 WeakPolarHBondContact O-CA 3.19Å; G344-P350 WeakPolarHBondContact O-CB 3.27Å; I348-P350 WeakPolarHBondContact O-CD 3.36Å; P350-L356 HydrophobicContact CG-CD2 4.13Å
351I90.4Very high89.5Confident77 Ų7748.6 Ų48.640%0.39526%0.264SS..SBendtrans-147.9-178.1176.2-157.3164.9000109.5L349 I355 L356L349-I351 VanDerWaalsContact C-N 3.31Å; L349-I351 PolarHBondContact O-N 2.9Å; I351-I355 HydrophobicContact CD1-CD1 4Å; I351-I355 HydrophobicContact CD1-CG2 4.4Å; I351-I355 HydrophobicContact CG1-CD1 4.12Å; I351-I355 HydrophobicContact CG2-CB 4.12Å; I351-I355 HydrophobicContact CG2-CG2 4.07Å; I351-L356 HydrophobicContact CG2-CD2 3.72Å; I351-L356 HydrophobicContact CG2-CG 3.72Å
352D87.2Confident89.8Confident43 Ų4350.1 Ų50.123%0.2328%0.28CS..  trans-56.4128.7-178.8-164.7-69000110.9I342 I354 I355 L356I342-D352 VanDerWaalsContact CD1-CA 3.45Å; I342-D352 HydrophobicContact CD1-CB 3.96Å; D352-I354 PolarHBondContact O-N 2.69Å; D352-I354 VanDerWaalsContact O-N 3.09Å; D352-I354 VanDerWaalsContact OD1-CB 3.32Å; D352-I354 WeakPolarHBondContact OD1-CB 3.47Å; D352-I354 WeakPolarHBondContact OD1-CG1 3.44Å; D352-I354 PolarHBondContact OD1-N 2.72Å; D352-I355 HydrophobicContact CB-CD1 4.14Å; D352-I355 HydrophobicContact CB-CG1 4.27Å; D352-I355 WeakPolarHBondContact O-CA 3.31Å; D352-I355 WeakPolarHBondContact O-CB 3.43Å; D352-I355 PolarHBondContact O-N 3.44Å; D352-L356 PolarHBondContact O-N 2.84Å
353P88.9Confident90.1Very high0 Ų049.2 Ų49.20%028%0.276CS..Hα-helixtrans-51.1-31.5177.1-32.438.6000114.5L223 L226 A244 F250 I355 L356 M357L223-P353 HydrophobicContact CD2-CB 4.22Å; L223-P353 HydrophobicContact CD2-CG 3.7Å; L226-P353 HydrophobicContact CD1-CB 3.83Å; A244-P353 HydrophobicContact CB-CB 4.45Å; F250-P353 HydrophobicContact CD1-CG 3.74Å; F250-P353 HydrophobicContact CE1-CB 4.2Å; F250-P353 HydrophobicContact CE1-CG 3.66Å; F250-P353 HydrophobicContact CE2-CG 4.49Å; F250-P353 HydrophobicContact CG-CG 4.2Å; F250-P353 HydrophobicContact CZ-CG 4.07Å; P353-I355 VanDerWaalsContact C-N 3.29Å; P353-I355 PolarHBondContact O-N 3.33Å; P353-L356 PolarHBondContact O-N 3.31Å; P353-M357 WeakPolarHBondContact O-CB 3.47Å; P353-M357 VanDerWaalsContact O-CG 3.27Å; P353-M357 WeakPolarHBondContact O-CG 3.43Å; P353-M357 PolarHBondContact O-N 3.28Å
354I85.2Confident90.5Very high46 Ų4649.6 Ų49.624%0.23628%0.279CS..Hα-helixtrans-63.5-38.3175.6-64.2171.5000110.9L245 D352 W405 I577L245-I354 HydrophobicContact CD2-CG1 3.68Å; D352-I354 PolarHBondContact O-N 2.69Å; D352-I354 VanDerWaalsContact O-N 3.09Å; D352-I354 VanDerWaalsContact OD1-CB 3.32Å; D352-I354 WeakPolarHBondContact OD1-CB 3.47Å; D352-I354 WeakPolarHBondContact OD1-CG1 3.44Å; D352-I354 PolarHBondContact OD1-N 2.72Å; I354-W405 HydrophobicContact CD1-CZ3 4.46Å; I354-I577 HydrophobicContact CG2-CD1 4.35Å; I354-I577 HydrophobicContact CG2-CG1 4.43Å
355I87.2Confident91.1Very high77 Ų7748.8 Ų48.840%0.39527%0.272SS..Hα-helixtrans-73.6-43.3176.5-61.5172.3000109.8I351 D352 P353 M357 Q358I351-I355 HydrophobicContact CD1-CD1 4Å; I351-I355 HydrophobicContact CD1-CG2 4.4Å; I351-I355 HydrophobicContact CG1-CD1 4.12Å; I351-I355 HydrophobicContact CG2-CB 4.12Å; I351-I355 HydrophobicContact CG2-CG2 4.07Å; D352-I355 HydrophobicContact CB-CD1 4.14Å; D352-I355 HydrophobicContact CB-CG1 4.27Å; D352-I355 WeakPolarHBondContact O-CA 3.31Å; D352-I355 WeakPolarHBondContact O-CB 3.43Å; D352-I355 PolarHBondContact O-N 3.44Å; P353-I355 VanDerWaalsContact C-N 3.29Å; P353-I355 PolarHBondContact O-N 3.33Å; I355-M357 PolarHBondContact O-N 2.77Å; I355-Q358 WeakPolarHBondContact O-CB 3.27Å; I355-Q358 PolarHBondContact O-N 3.14Å
356L89.6Confident91.7Very high31 Ų3145 Ų4516%0.16224%0.24CC..Hα-helixtrans-59.4-32176.4-69.1174.1000112.6L226 P350 I351 D352 P353 Q358 D359 R360L226-L356 HydrophobicContact CB-CB 4.05Å; L226-L356 HydrophobicContact CB-CD1 4.06Å; L226-L356 HydrophobicContact CD1-CB 4.27Å; L226-L356 HydrophobicContact CD2-CB 4.42Å; L226-L356 HydrophobicContact CG-CB 4.48Å; P350-L356 HydrophobicContact CG-CD2 4.13Å; I351-L356 HydrophobicContact CG2-CD2 3.72Å; I351-L356 HydrophobicContact CG2-CG 3.72Å; D352-L356 PolarHBondContact O-N 2.84Å; P353-L356 PolarHBondContact O-N 3.31Å; L356-Q358 PolarHBondContact O-N 3.48Å; L356-D359 CarbonylContact O-C 3.38Å; L356-D359 PolarHBondContact O-N 3.01Å; L356-R360 WeakPolarHBondContact O-CB 2.93Å; L356-R360 PolarHBondContact O-N 3.1Å
357M90.3Very high92.2Very high9 Ų938.1 Ų38.14%0.04420%0.203CC..G310 helixtrans-67.4-20.5177.2-80-173.5179.500114.2L226 A244 L245 P353 I355 D359 D459 T462L226-M357 HydrophobicContact CD1-CE 3.98Å; L226-M357 HydrophobicContact CD1-CG 3.99Å; L226-M357 HydrophobicContact CD2-CG 3.7Å; A244-M357 HydrophobicContact CB-CE 3.8Å; L245-M357 HydrophobicContact CD1-CE 4.15Å; L245-M357 HydrophobicContact CD1-SD 3.66Å; L245-M357 HydrophobicContact CD2-CE 4Å; L245-M357 HydrophobicContact CD2-SD 3.68Å; L245-M357 HydrophobicContact CG-CE 3.68Å; L245-M357 HydrophobicContact CG-SD 3.68Å; P353-M357 WeakPolarHBondContact O-CB 3.47Å; P353-M357 VanDerWaalsContact O-CG 3.27Å; P353-M357 WeakPolarHBondContact O-CG 3.43Å; P353-M357 PolarHBondContact O-N 3.28Å; I355-M357 PolarHBondContact O-N 2.77Å; M357-D359 VanDerWaalsContact C-N 3.34Å; M357-D459 HydrophobicContact CE-CB 4.36Å; M357-T462 HydrophobicContact CB-CG2 4.04Å; M357-T462 HydrophobicContact SD-CG2 4.02Å; M357-T462 PolarHBondContact SD-OG1 3.13Å
358Q85.1Confident92.4Very high110 Ų11037.5 Ų37.551%0.51420%0.197SC..G310 helixtrans-70.5-31.9179-64.9177.1-3.300112.5I355 L356I355-Q358 WeakPolarHBondContact O-CB 3.27Å; I355-Q358 PolarHBondContact O-N 3.14Å; L356-Q358 PolarHBondContact O-N 3.48Å
359D84.5Confident92.5Very high156 Ų15637.1 Ų37.183%0.83420%0.195SC*.G310 helixtrans-129.745.9178.9-167.429.7000110.1L356 M357L356-D359 CarbonylContact O-C 3.38Å; L356-D359 PolarHBondContact O-N 3.01Å; M357-D359 VanDerWaalsContact C-N 3.34Å
360R93.8Very high92.5Very high13 Ų1337.1 Ų37.15%0.04920%0.195CC..PPolyproline II helixtrans-79.1150178.268.8-174.1-60.3-177.73.4110.9T225 L226 L356 S362 D459 T462 M463 A466T225-R360 PolarHBondContact OG1-NH2 2.64Å; L226-R360 HydrophobicContact CD2-CB 3.72Å; L356-R360 WeakPolarHBondContact O-CB 2.93Å; L356-R360 PolarHBondContact O-N 3.1Å; R360-S362 PolarHBondContact O-N 3.46Å; R360-D459 IonicContact CZ-OD1 2.69Å; R360-D459 PolarHBondContact NH1-O 3.2Å; R360-D459 IonicContact NH1-OD1 3.52Å; R360-D459 PolarHBondContact NH1-OD1 3.12Å; R360-D459 IonicContact NH2-OD1 3.6Å; R360-D459 PolarHBondContact NH2-OD1 2.88Å; R360-T462 PolarHBondContact NH1-OG1 3.46Å; R360-M463 VanDerWaalsContact NH2-CE 3.29Å; R360-A466 HydrophobicContact CG-CB 3.68Å
361R94.3Very high92.5Very high73 Ų7341.1 Ų41.128%0.27521%0.209SC..PPolyproline II helixtrans-64.6132.3170.9-61180-65.8112.6-7.4110.3T225 S227 T230T225-R361 PolarHBondContact O-NH2 3.43Å; S227-R361 PolarHBondContact O-NH2 2.92Å; T230-R361 PolarHBondContact OG1-NH2 2.67Å
362S95.4Very high92.4Very high70 Ų7037.7 Ų37.749%0.4919%0.192SC..PPolyproline II helixtrans-79.9145.4172.954.30000112R360 A466R360-S362 PolarHBondContact O-N 3.46Å; S362-A466 VanDerWaalsContact CB-O 3.27Å; S362-A466 WeakPolarHBondContact CB-O 3.36Å
363M97.4Very high92.5Very high12 Ų1236 Ų366%0.05918%0.183CC..  trans-159.3163.3175.259.9-173.171.800109.6T225 M234 A237 Y365 M463 G468T225-M363 HydrophobicContact CG2-CE 4.49Å; T225-M363 HydrophobicContact CG2-SD 4.08Å; M234-M363 HydrophobicContact CE-CE 4.24Å; M234-M363 HydrophobicContact CE-SD 4.39Å; A237-M363 HydrophobicContact CB-SD 4.29Å; M363-Y365 PolarHBondContact O-N 3.03Å; M363-M463 HydrophobicContact CG-CE 3.6Å; M363-M463 HydrophobicContact CG-SD 4.13Å; M363-M463 HydrophobicContact SD-CE 4.25Å; M363-G468 WeakPolarHBondContact O-CA 3.48Å
364P98.6Very high92.2Very high32 Ų3239.1 Ų39.121%0.20820%0.197CC..  trans-57.3131.4163.9-20.332.4000110.3E235 Q236 A237 F520E235-P364 WeakPolarHBondContact O-CD 3.25Å; Q236-P364 WeakPolarHBondContact CA-O 3.35Å; Q236-P364 HydrophobicContact CB-CB 3.86Å; Q236-P364 HydrophobicContact CB-CG 4.21Å; Q236-P364 VanDerWaalsContact CB-O 3.31Å; Q236-P364 WeakPolarHBondContact CB-O 3.15Å; A237-P364 PolarHBondContact N-O 3.19Å; P364-F520 HydrophobicContact CB-CE2 3.99Å; P364-F520 HydrophobicContact CB-CZ 3.92Å
365Y98.6Very high91.5Very high0 Ų038.9 Ų38.90%020%0.197CC..EExtended strand (participates in β ladder)trans-141.8113.4-170-158.6-125.4000110.9S222 T225 A237 V239 M363 L367 D459 M463 T469 V470 Y471S222-Y365 PolarHBondContact OG-OH 3.48Å; T225-Y365 HydrophobicContact CG2-CE2 3.91Å; A237-Y365 HydrophobicContact CB-CD2 3.78Å; A237-Y365 HydrophobicContact CB-CE2 3.73Å; V239-Y365 HydrophobicContact CG2-CE2 3.75Å; V239-Y365 WeakPolarHBondContact CG2-OH 3.32Å; M363-Y365 PolarHBondContact O-N 3.03Å; Y365-L367 HydrophobicContact CD1-CD1 4.19Å; Y365-L367 HydrophobicContact CD1-CD2 3.94Å; Y365-L367 HydrophobicContact CE1-CD1 3.72Å; Y365-L367 HydrophobicContact CE1-CD2 4.33Å; Y365-L367 HydrophobicContact CE1-CG 4.44Å; Y365-D459 WeakPolarHBondContact CE1-OD1 3.39Å; Y365-D459 PolarHBondContact OH-OD1 2.97Å; Y365-D459 PolarHBondContact OH-OD2 3.36Å; Y365-M463 HydrophobicContact CD1-CB 3.84Å; Y365-M463 HydrophobicContact CD1-CE 4.13Å; Y365-M463 HydrophobicContact CD1-CG 3.76Å; Y365-M463 HydrophobicContact CD2-CE 3.68Å; Y365-M463 HydrophobicContact CE1-CB 4.3Å; Y365-M463 HydrophobicContact CE1-CE 4.37Å; Y365-M463 HydrophobicContact CE2-CE 3.99Å; Y365-M463 HydrophobicContact CG-CB 4.4Å; Y365-M463 HydrophobicContact CG-CE 3.77Å; Y365-M463 HydrophobicContact CG-CG 3.81Å; Y365-T469 PolarHBondContact N-O 3.31Å; Y365-V470 CarbonylContact O-C 3.13Å; Y365-V470 VanDerWaalsContact O-CA 3.26Å; Y365-V470 WeakPolarHBondContact O-CA 3.42Å; Y365-Y471 PolarHBondContact O-N 3Å
366L98.7Very high90Very high1 Ų141.9 Ų41.91%0.00521%0.21CC..EExtended strand (participates in β ladder)trans-105.5124.4175-169.4160.4000108.2A237 I238 V239 Y471 Y473 L517 F520 P526 W536A237-L366 PolarHBondContact O-N 3.44Å; I238-L366 CarbonylContact C-O 3.44Å; I238-L366 VanDerWaalsContact CA-O 3.24Å; I238-L366 WeakPolarHBondContact CA-O 3.23Å; I238-L366 HydrophobicContact CG1-CB 4.27Å; I238-L366 HydrophobicContact CG2-CD2 4.17Å; V239-L366 PolarHBondContact N-O 3.07Å; L366-Y471 WeakPolarHBondContact CA-O 3.5Å; L366-Y473 HydrophobicContact CD2-CD1 3.82Å; L366-Y473 HydrophobicContact CD2-CE1 3.72Å; L366-L517 HydrophobicContact CD1-CD2 4.43Å; L366-L517 HydrophobicContact CD2-CD2 4.28Å; L366-F520 HydrophobicContact CB-CD1 3.94Å; L366-F520 HydrophobicContact CB-CD2 4.17Å; L366-F520 HydrophobicContact CB-CE1 3.74Å; L366-F520 HydrophobicContact CB-CE2 4Å; L366-F520 HydrophobicContact CB-CG 4.14Å; L366-F520 HydrophobicContact CB-CZ 3.77Å; L366-F520 HydrophobicContact CD1-CB 3.84Å; L366-F520 HydrophobicContact CD1-CD1 4.07Å; L366-F520 HydrophobicContact CD1-CD2 4.09Å; L366-F520 HydrophobicContact CD1-CG 3.72Å; L366-P526 HydrophobicContact CD1-CB 4.39Å; L366-W536 HydrophobicContact CD1-CH2 4.08Å; L366-W536 HydrophobicContact CD1-CZ3 4.14Å; L366-W536 HydrophobicContact CD2-CH2 4.19Å; L366-W536 HydrophobicContact CG-CH2 4.1Å
367L98.3Very high88Confident0 Ų043.3 Ų43.30%022%0.223CC..EExtended strand (participates in β ladder)trans-144.8160.717775.6175.1000112.8V239 Y365 V456 D459 A460 V470 Y471 L472 Y473V239-L367 HydrophobicContact CB-CB 3.97Å; V239-L367 WeakPolarHBondContact O-CA 3.33Å; V239-L367 VanDerWaalsContact O-CB 3.32Å; V239-L367 WeakPolarHBondContact O-CB 3.49Å; Y365-L367 HydrophobicContact CD1-CD1 4.19Å; Y365-L367 HydrophobicContact CD1-CD2 3.94Å; Y365-L367 HydrophobicContact CE1-CD1 3.72Å; Y365-L367 HydrophobicContact CE1-CD2 4.33Å; Y365-L367 HydrophobicContact CE1-CG 4.44Å; L367-V456 HydrophobicContact CD1-CG1 3.83Å; L367-V456 WeakPolarHBondContact CD1-O 3.5Å; L367-V456 HydrophobicContact CG-CG1 3.98Å; L367-D459 HydrophobicContact CD1-CB 4.18Å; L367-A460 HydrophobicContact CD1-CB 3.9Å; L367-A460 HydrophobicContact CD2-CB 3.77Å; L367-A460 HydrophobicContact CG-CB 4.22Å; L367-V470 HydrophobicContact CD2-CG1 3.45Å; L367-V470 VanDerWaalsContact CD2-CG1 3.45Å; L367-Y471 PolarHBondContact N-O 3.45Å; L367-Y471 VanDerWaalsContact O-O 3.09Å; L367-L472 HydrophobicContact CD2-CD1 4.34Å; L367-L472 HydrophobicContact CG-CD1 4.12Å; L367-L472 CarbonylContact O-C 3.55Å; L367-L472 VanDerWaalsContact O-CA 3.26Å; L367-L472 WeakPolarHBondContact O-CA 3.39Å; L367-Y473 WeakPolarHBondContact O-CD1 3.17Å; L367-Y473 PolarHBondContact O-N 3.31Å
368G96.4Very high86Confident0 Ų051.1 Ų51.10%026%0.256CS..EExtended strand (participates in β ladder)trans175-174.4177.900000113V239 S241 Y473V239-G368 PolarHBondContact O-N 2.76Å; S241-G368 PolarHBondContact N-O 3.03Å; G368-Y473 VanDerWaalsContact CA-CE1 3.43Å; G368-Y473 WeakPolarHBondContact CA-O 3.38Å
369T96.6Very high84Confident0 Ų053.4 Ų53.40%027%0.272CS..EExtended strand (participates in β ladder)trans-139.9160.7-17268.30000110.6E373 I452 F453 V456 Y473 S474 F475 Y560T369-E373 WeakPolarHBondContact CB-OE1 3.38Å; T369-I452 HydrophobicContact CG2-CG2 3.43Å; T369-I452 VanDerWaalsContact CG2-CG2 3.43Å; T369-F453 HydrophobicContact CG2-CD1 4.01Å; T369-F453 HydrophobicContact CG2-CE1 4.45Å; T369-F453 WeakPolarHBondContact OG1-CE1 3.24Å; T369-V456 HydrophobicContact CG2-CB 4Å; T369-V456 HydrophobicContact CG2-CG1 3.96Å; T369-V456 HydrophobicContact CG2-CG2 3.82Å; T369-Y473 PolarHBondContact N-O 3.32Å; T369-S474 CarbonylContact O-C 3.51Å; T369-S474 VanDerWaalsContact O-CA 3.28Å; T369-S474 WeakPolarHBondContact O-CA 3.35Å; T369-F475 PolarHBondContact O-N 3.35Å; T369-Y560 WeakPolarHBondContact CB-OH 3.23Å; T369-Y560 WeakPolarHBondContact CG2-OH 3.39Å; T369-Y560 PolarHBondContact OG1-OH 3.1Å
370T94.8Very high81.8Confident0 Ų052.5 Ų52.50%026%0.261CS..EExtended strand (participates in β ladder)trans-73.3153.4158.966.40000110.3G372 E373 F453 V489 D490T370-G372 PolarHBondContact O-N 3.2Å; T370-E373 WeakPolarHBondContact CA-OE1 3.4Å; T370-E373 WeakPolarHBondContact CB-OE1 3.2Å; T370-E373 PolarHBondContact N-OE1 2.88Å; T370-E373 PolarHBondContact OG1-OE1 2.67Å; T370-F453 VanDerWaalsContact O-CE1 3.28Å; T370-F453 WeakPolarHBondContact O-CE1 3.31Å; T370-V489 HydrophobicContact CG2-CG1 3.87Å; T370-D490 HydrophobicContact CG2-CB 4.46Å
371K91.3Very high78.9Confident114 Ų11456.7 Ų56.750%0.49629%0.288SS..THydrogen-bonded Turntrans-63.8-19.9176.6-165.3-178.6-173.3171.30113.6F475 D476K371-F475 PolarHBondContact N-O 2.85Å; K371-D476 WeakPolarHBondContact CB-OD1 3.47Å; K371-D476 HydrophobicContact CD-CB 4.34Å; K371-D476 VanDerWaalsContact CD-OD1 3.3Å; K371-D476 WeakPolarHBondContact CD-OD1 3.19Å; K371-D476 WeakPolarHBondContact CG-OD1 3.48Å
372G87.6Confident75.9Confident4 Ų457.7 Ų57.74%0.04131%0.312CS..BIsolated β-bridgetrans-134.456.9-170.500000114.3T370 F374 T375 T485 P486 H487T370-G372 PolarHBondContact O-N 3.2Å; G372-F374 VanDerWaalsContact C-N 3.31Å; G372-F374 PolarHBondContact O-N 3.3Å; G372-T375 VanDerWaalsContact O-CG2 3.31Å; G372-T375 WeakPolarHBondContact O-CG2 3.47Å; G372-T375 PolarHBondContact O-N 3.42Å; G372-T375 PolarHBondContact O-OG1 2.72Å; G372-T485 CarbonylContact C-O 3.44Å; G372-T485 WeakPolarHBondContact CA-O 3.23Å; G372-T485 PolarHBondContact N-O 2.9Å; G372-P486 WeakPolarHBondContact O-CA 3.16Å; G372-H487 PolarHBondContact O-N 2.95Å
373E89.5Confident72.8Confident9 Ų960.8 Ų60.84%0.04233%0.327CS..THydrogen-bonded Turntrans-51.2-42.8-176.5-66.2-65.3149.400114.5S241 T369 T370 I452 F453 H487S241-E373 WeakPolarHBondContact CB-OE1 3.4Å; S241-E373 PolarHBondContact OG-OE1 3.11Å; S241-E373 VanDerWaalsContact OG-OE1 3.05Å; T369-E373 WeakPolarHBondContact CB-OE1 3.38Å; T370-E373 WeakPolarHBondContact CA-OE1 3.4Å; T370-E373 WeakPolarHBondContact CB-OE1 3.2Å; T370-E373 PolarHBondContact N-OE1 2.88Å; T370-E373 PolarHBondContact OG1-OE1 2.67Å; E373-I452 HydrophobicContact CB-CB 4.3Å; E373-I452 HydrophobicContact CB-CG1 4.24Å; E373-I452 HydrophobicContact CG-CB 3.87Å; E373-I452 HydrophobicContact CG-CG1 4.18Å; E373-I452 HydrophobicContact CG-CG2 3.68Å; E373-F453 HydrophobicContact CB-CE1 4.43Å; E373-F453 HydrophobicContact CG-CD1 4.15Å; E373-F453 HydrophobicContact CG-CE1 3.51Å; E373-F453 HydrophobicContact CG-CZ 4.3Å; E373-H487 VanDerWaalsContact O-CB 3.27Å; E373-H487 WeakPolarHBondContact O-CB 3.47Å; E373-H487 IonicContact OE2-CE1 3.1Å; E373-H487 IonicContact OE2-CG 2.79Å; E373-H487 IonicContact OE2-ND1 2.65Å; E373-H487 PolarHBondContact OE2-ND1 3.27Å
374F84.1Confident69.8Low64 Ų6463.9 Ų63.928%0.28136%0.355SS..THydrogen-bonded Turntrans-117.135.6-178.9-59.8-74.9000113G372 E376 R447 N448 I452G372-F374 VanDerWaalsContact C-N 3.31Å; G372-F374 PolarHBondContact O-N 3.3Å; F374-E376 PolarHBondContact O-N 3.02Å; F374-R447 HydrophobicContact CB-CB 4.18Å; F374-R447 VanDerWaalsContact CD2-C 3.49Å; F374-R447 HydrophobicContact CD2-CB 3.98Å; F374-R447 VanDerWaalsContact CD2-O 3.31Å; F374-R447 WeakPolarHBondContact CD2-O 3.46Å; F374-R447 WeakPolarHBondContact CE2-O 3.23Å; F374-R447 HydrophobicContact CG-CB 4.18Å; F374-N448 WeakPolarHBondContact CB-OD1 3.23Å; F374-N448 WeakPolarHBondContact CD2-OD1 3.41Å; F374-N448 PolarHBondContact N-OD1 2.77Å; F374-I452 HydrophobicContact CE2-CB 4.5Å; F374-I452 HydrophobicContact CE2-CG1 3.81Å; F374-I452 HydrophobicContact CZ-CG1 3.96Å
375T70.1Confident66.9Low41 Ų4165.9 Ų65.925%0.25237%0.374SS..  trans-63.8130.317557.50000111G372 S377 S484 P486G372-T375 VanDerWaalsContact O-CG2 3.31Å; G372-T375 WeakPolarHBondContact O-CG2 3.47Å; G372-T375 PolarHBondContact O-N 3.42Å; G372-T375 PolarHBondContact O-OG1 2.72Å; T375-S377 PolarHBondContact O-N 2.76Å; T375-S484 WeakPolarHBondContact CB-OG 3.41Å; T375-S484 WeakPolarHBondContact CG2-OG 3.45Å; T375-S484 PolarHBondContact OG1-OG 3.22Å; T375-P486 WeakPolarHBondContact OG1-CB 3.48Å
376E54.5Low63.9Low140 Ų14073.9 Ų73.965%0.65441%0.412SS*.  trans-72.8123.9172-71.4-177.9169.400109.8F374 K378F374-E376 PolarHBondContact O-N 3.02Å; E376-K378 PolarHBondContact O-N 3.38Å
377S49.2Very low61.4Low62 Ų6282.5 Ų82.543%0.43445%0.452SS..  trans-68114.3169.8610000108.4T375 N379 K380T375-S377 PolarHBondContact O-N 2.76Å; S377-N379 PolarHBondContact O-N 2.75Å; S377-K380 PolarHBondContact O-N 3.01Å; S377-K380 WeakPolarHBondContact OG-CG 3.29Å
378K46.8Very low60Low172 Ų17289.5 Ų89.575%0.74849%0.485SS*.THydrogen-bonded Turntrans-52-24.7171.5-71-178.8179.2165.20113.1E376 K380 D483E376-K378 PolarHBondContact O-N 3.38Å; K378-K380 VanDerWaalsContact C-N 3.32Å; K378-K380 PolarHBondContact O-N 2.91Å; K378-D483 WeakPolarHBondContact CE-OD2 3.46Å; K378-D483 IonicContact NZ-OD2 3.47Å; K378-D483 PolarHBondContact NZ-OD2 3.35Å
379N43.5Very low59.3Low158 Ų15890 Ų9085%0.84549%0.489SS*.THydrogen-bonded Turntrans-78.6-1.3177.5-80.3-0.8000115.6S377 T381S377-N379 PolarHBondContact O-N 2.75Å; N379-T381 VanDerWaalsContact C-N 3.26Å; N379-T381 PolarHBondContact O-N 2.98Å
380K38.8Very low58.9Low137 Ų13793.1 Ų93.160%0.59651%0.508SS*.SBendtrans-70.695.6166-91.1174.9-174.51780106.8S377 K378S377-K380 PolarHBondContact O-N 3.01Å; S377-K380 WeakPolarHBondContact OG-CG 3.29Å; K378-K380 VanDerWaalsContact C-N 3.32Å; K378-K380 PolarHBondContact O-N 2.91Å
381T32.6Very low58.5Low101 Ų10194.6 Ų94.662%0.6252%0.517SS*.  trans12.8115.7159.851.20000113.5N379 V383 A384N379-T381 VanDerWaalsContact C-N 3.26Å; N379-T381 PolarHBondContact O-N 2.98Å; T381-V383 PolarHBondContact O-N 2.81Å; T381-A384 PolarHBondContact O-N 2.78Å; T381-A384 VanDerWaalsContact O-N 3.07Å
382A30.4Very low58.3Low95 Ų9590.3 Ų90.379%0.78550%0.5SS*.THydrogen-bonded Turntrans-47.13173.500000116.8A385A382-A385 WeakPolarHBondContact O-CA 3.32Å; A382-A385 PolarHBondContact O-N 3.15Å
383V31.5Very low58.2Low134 Ų13492.6 Ų92.681%0.81251%0.513SS*.THydrogen-bonded Turntrans-75.1-28.3170.4-173.40000112.1T381 A385T381-V383 PolarHBondContact O-N 2.81Å; V383-A385 PolarHBondContact O-N 3.22Å
384A35Very low58.2Low78 Ų7892.1 Ų92.165%0.64551%0.511SS*.SBendtrans-81.163.4153.900000106.8T381 E386T381-A384 PolarHBondContact O-N 2.78Å; T381-A384 VanDerWaalsContact O-N 3.07Å; A384-E386 PolarHBondContact O-N 2.98Å; A384-E386 VanDerWaalsContact O-N 3.11Å
385A36.3Very low58.4Low73 Ų7389.5 Ų89.560%0.60350%0.5SS*.  trans-45.4123166.300000106.3A382 V383 E387A382-A385 WeakPolarHBondContact O-CA 3.32Å; A382-A385 PolarHBondContact O-N 3.15Å; V383-A385 PolarHBondContact O-N 3.22Å; A385-E387 VanDerWaalsContact C-N 3.3Å; A385-E387 PolarHBondContact O-N 3Å
386E35.7Very low59.1Low169 Ų16991.7 Ų91.779%0.7951%0.509SS*.  trans-44.491.1-178.1-63.5168.314900110.2A384 Q388A384-E386 PolarHBondContact O-N 2.98Å; A384-E386 VanDerWaalsContact O-N 3.11Å; E386-Q388 HydrophobicContact CB-CG 4.47Å; E386-Q388 PolarHBondContact O-N 3.42Å
387E46.5Very low60.6Low182 Ų18286 Ų8685%0.8549%0.486SS*.  trans-6785.4146.1-86.1-173.7169.600103.7A385 A389A385-E387 VanDerWaalsContact C-N 3.3Å; A385-E387 PolarHBondContact O-N 3Å; E387-A389 PolarHBondContact O-N 2.81Å
388Q69.4Low62.4Low146 Ų14683 Ų8368%0.68247%0.466SS*.  trans-43.2119.3161.4-75.2-175.6-8.900105.2E386 T390E386-Q388 HydrophobicContact CB-CG 4.47Å; E386-Q388 PolarHBondContact O-N 3.42Å; Q388-T390 PolarHBondContact O-N 3.02Å
389A82Confident64.2Low11 Ų1179.5 Ų79.59%0.09145%0.451CS..  trans-54.1137.2-174.500000107.7E387 T393 W439 S440 V443E387-A389 PolarHBondContact O-N 2.81Å; A389-T393 HydrophobicContact CB-CG2 4.06Å; A389-W439 HydrophobicContact CB-CB 3.93Å; A389-W439 WeakPolarHBondContact O-CB 3.04Å; A389-S440 PolarHBondContact N-OG 3.24Å; A389-S440 VanDerWaalsContact N-OG 3.12Å; A389-V443 HydrophobicContact CB-CG2 3.97Å
390T86.8Confident65.9Low65 Ų6576.1 Ų76.140%0.39943%0.428SS..  trans-97.4167177.365.60000108.5Q388 L392 T393 L394Q388-T390 PolarHBondContact O-N 3.02Å; T390-L392 PolarHBondContact O-N 3.04Å; T390-L392 PolarHBondContact OG1-N 3.4Å; T390-T393 PolarHBondContact N-OG1 3.28Å; T390-T393 WeakPolarHBondContact O-CA 3.45Å; T390-T393 VanDerWaalsContact O-CB 3.26Å; T390-T393 WeakPolarHBondContact O-CB 3.24Å; T390-T393 PolarHBondContact O-N 3.33Å; T390-T393 PolarHBondContact OG1-N 2.78Å; T390-T393 VanDerWaalsContact OG1-N 3.15Å; T390-T393 PolarHBondContact OG1-OG1 2.78Å; T390-L394 PolarHBondContact O-N 2.9Å; T390-L394 VanDerWaalsContact O-N 3.1Å
391P87Confident67.8Low31 Ų3170.3 Ų70.320%0.20140%0.404CS..Hα-helixtrans-51.8-38166-25.832.6000113T393 L394 L395 F420 W439 I608 I612P391-T393 VanDerWaalsContact C-N 3.34Å; P391-T393 PolarHBondContact O-N 3.39Å; P391-L394 PolarHBondContact O-N 3.48Å; P391-L395 PolarHBondContact O-N 3.12Å; P391-F420 HydrophobicContact CB-CE2 4.29Å; P391-F420 HydrophobicContact CB-CZ 4.18Å; P391-F420 WeakPolarHBondContact O-CE2 3.14Å; P391-W439 HydrophobicContact CB-CH2 4.44Å; P391-W439 HydrophobicContact CB-CZ2 4.29Å; P391-W439 HydrophobicContact CG-CD2 4.18Å; P391-W439 HydrophobicContact CG-CH2 4.22Å; P391-W439 HydrophobicContact CG-CZ2 3.6Å; P391-I608 HydrophobicContact CB-CG2 3.93Å; P391-I608 HydrophobicContact CG-CG2 4.17Å; P391-I612 HydrophobicContact CB-CD1 3.08Å; P391-I612 HydrophobicContact CB-CG1 3.96Å; P391-I612 HydrophobicContact CG-CD1 4.25Å
392L86.8Confident70Confident24 Ų2465.5 Ų65.513%0.12638%0.375CS..Hα-helixtrans-63.2-40.2175-179.961.3000111.8T390 L394 L395 L396 I612 A616T390-L392 PolarHBondContact O-N 3.04Å; T390-L392 PolarHBondContact OG1-N 3.4Å; L392-L394 VanDerWaalsContact C-N 3.31Å; L392-L394 PolarHBondContact O-N 3.02Å; L392-L395 PolarHBondContact O-N 2.94Å; L392-L396 HydrophobicContact CD1-CD1 4.26Å; L392-L396 HydrophobicContact CD1-CG 4.12Å; L392-L396 HydrophobicContact CG-CD1 4.06Å; L392-L396 HydrophobicContact CG-CG 4.35Å; L392-L396 WeakPolarHBondContact O-CB 3.41Å; L392-L396 VanDerWaalsContact O-CG 3.31Å; L392-L396 WeakPolarHBondContact O-CG 3.19Å; L392-L396 PolarHBondContact O-N 3.37Å; L392-I612 HydrophobicContact CB-CG2 3.94Å; L392-I612 HydrophobicContact CD1-CG2 3.64Å; L392-I612 HydrophobicContact CG-CG2 4.4Å; L392-A616 HydrophobicContact CD1-CB 4.09Å
393T86.4Confident71.9Confident52 Ų5263.7 Ų63.732%0.31935%0.354SS..Hα-helixtrans-57.9-44.5174.8-47.70000111.2A389 T390 P391 L396 A397 V443A389-T393 HydrophobicContact CB-CG2 4.06Å; T390-T393 PolarHBondContact N-OG1 3.28Å; T390-T393 WeakPolarHBondContact O-CA 3.45Å; T390-T393 VanDerWaalsContact O-CB 3.26Å; T390-T393 WeakPolarHBondContact O-CB 3.24Å; T390-T393 PolarHBondContact O-N 3.33Å; T390-T393 PolarHBondContact OG1-N 2.78Å; T390-T393 VanDerWaalsContact OG1-N 3.15Å; T390-T393 PolarHBondContact OG1-OG1 2.78Å; P391-T393 VanDerWaalsContact C-N 3.34Å; P391-T393 PolarHBondContact O-N 3.39Å; T393-L396 PolarHBondContact O-N 3.34Å; T393-A397 WeakPolarHBondContact O-CB 3.38Å; T393-A397 PolarHBondContact O-N 3.3Å; T393-V443 HydrophobicContact CG2-CG2 4.37Å
394L88.7Confident73.6Confident0 Ų059.8 Ų59.80%033%0.328CS..Hα-helixtrans-64.6-43.8176.1179.661.1000111.9T390 P391 L392 L396 A397 C398 F420 W439 A442 V443 L446T390-L394 PolarHBondContact O-N 2.9Å; T390-L394 VanDerWaalsContact O-N 3.1Å; P391-L394 PolarHBondContact O-N 3.48Å; L392-L394 VanDerWaalsContact C-N 3.31Å; L392-L394 PolarHBondContact O-N 3.02Å; L394-L396 VanDerWaalsContact C-N 3.35Å; L394-L396 PolarHBondContact O-N 3.4Å; L394-A397 PolarHBondContact O-N 2.93Å; L394-C398 PolarHBondContact O-N 3.07Å; L394-F420 HydrophobicContact CB-CD2 4.31Å; L394-F420 HydrophobicContact CB-CE2 4.19Å; L394-F420 HydrophobicContact CD2-CD2 4Å; L394-F420 HydrophobicContact CD2-CE2 4Å; L394-F420 HydrophobicContact CG-CD2 3.98Å; L394-F420 HydrophobicContact CG-CE2 4.21Å; L394-W439 HydrophobicContact CD2-CE3 3.91Å; L394-W439 HydrophobicContact CD2-CZ3 3.9Å; L394-A442 HydrophobicContact CD2-CB 4.5Å; L394-V443 HydrophobicContact CB-CG2 4.07Å; L394-V443 HydrophobicContact CD1-CG2 4.01Å; L394-L446 HydrophobicContact CD1-CD2 3.89Å
395L88Confident74.9Confident8 Ų858.5 Ų58.54%0.04231%0.306CS..Hα-helixtrans-60.9-44.2178.2-174.369.9000111.8P391 L392 C398 K399 V416 F420 L609 I612 F613 A616P391-L395 PolarHBondContact O-N 3.12Å; L392-L395 PolarHBondContact O-N 2.94Å; L395-C398 PolarHBondContact O-N 3.1Å; L395-K399 PolarHBondContact O-N 3.06Å; L395-V416 HydrophobicContact CD1-CG1 3.51Å; L395-V416 HydrophobicContact CG-CG1 4.32Å; L395-F420 HydrophobicContact CB-CD2 4Å; L395-F420 HydrophobicContact CB-CE2 4.38Å; L395-F420 HydrophobicContact CD1-CB 4.2Å; L395-F420 HydrophobicContact CD1-CD2 4.12Å; L395-F420 HydrophobicContact CD1-CG 4.37Å; L395-L609 HydrophobicContact CD1-CD1 4.11Å; L395-I612 HydrophobicContact CB-CG2 4.29Å; L395-I612 HydrophobicContact CD2-CB 4.39Å; L395-I612 HydrophobicContact CD2-CG2 3.56Å; L395-F613 HydrophobicContact CD1-CD2 4.15Å; L395-F613 HydrophobicContact CD1-CE2 3.47Å; L395-F613 VanDerWaalsContact CD1-CE2 3.47Å; L395-F613 HydrophobicContact CD1-CZ 3.98Å; L395-F613 HydrophobicContact CD2-CD2 4.11Å; L395-F613 HydrophobicContact CD2-CE2 4.15Å; L395-F613 HydrophobicContact CG-CE2 4.46Å; L395-A616 HydrophobicContact CD2-CB 4.37Å
396L84.8Confident76.1Confident87 Ų8762.8 Ų62.846%0.45531%0.311SS..Hα-helixtrans-66.7-37.6176.8-68.6175.8000111.8L392 T393 L394 K399 K400L392-L396 HydrophobicContact CD1-CD1 4.26Å; L392-L396 HydrophobicContact CD1-CG 4.12Å; L392-L396 HydrophobicContact CG-CD1 4.06Å; L392-L396 HydrophobicContact CG-CG 4.35Å; L392-L396 WeakPolarHBondContact O-CB 3.41Å; L392-L396 VanDerWaalsContact O-CG 3.31Å; L392-L396 WeakPolarHBondContact O-CG 3.19Å; L392-L396 PolarHBondContact O-N 3.37Å; T393-L396 PolarHBondContact O-N 3.34Å; L394-L396 VanDerWaalsContact C-N 3.35Å; L394-L396 PolarHBondContact O-N 3.4Å; L396-K399 PolarHBondContact O-N 3.01Å; L396-K400 WeakPolarHBondContact O-CB 3.23Å; L396-K400 PolarHBondContact O-N 3.5Å
397A85.6Confident76.9Confident21 Ų2156.1 Ų56.117%0.17428%0.281CS..Hα-helixtrans-63.5-45.317400000111.5T393 L394 K399 K400 V401 L446T393-A397 WeakPolarHBondContact O-CB 3.38Å; T393-A397 PolarHBondContact O-N 3.3Å; L394-A397 PolarHBondContact O-N 2.93Å; A397-K399 PolarHBondContact O-N 3.3Å; A397-K400 PolarHBondContact O-N 2.85Å; A397-V401 WeakPolarHBondContact O-CG2 3.31Å; A397-V401 PolarHBondContact O-N 3.23Å; A397-L446 HydrophobicContact CB-CD2 3.61Å
398C87.8Confident76.9Confident0 Ų056.9 Ų56.90%028%0.276CS..Hα-helixtrans-58.1-47.8173.1-83.80000111.5L394 L395 K400 V401 L402 C419 F420L394-C398 PolarHBondContact O-N 3.07Å; L395-C398 PolarHBondContact O-N 3.1Å; C398-K400 PolarHBondContact O-N 3.44Å; C398-V401 PolarHBondContact O-N 2.04Å; C398-L402 VanDerWaalsContact O-CG 3.24Å; C398-L402 WeakPolarHBondContact O-CG 3.48Å; C398-L402 PolarHBondContact O-N 3.33Å; C398-L402 VanDerWaalsContact O-N 3.11Å; C398-C419 VanDerWaalsContact CA-SG 3.57Å; C398-C419 HydrophobicContact CB-CB 3.73Å; C398-C419 WeakPolarHBondContact CB-SG 2.89Å; C398-C419 WeakPolarHBondContact SG-CB 3.5Å; C398-C419 CovalentContact SG-SG 2.05Å; C398-C419 PolarHBondContact SG-SG 2.99Å; C398-F420 PolarHBondContact SG-N 2.98Å; C398-F420 VanDerWaalsContact SG-N 3.44Å
399K84.2Confident75.9Confident98 Ų9859.9 Ų59.943%0.42629%0.287SS..Hα-helixtrans-57-48.5174.9-175.9-175173.9-164.90111.7L395 L396 A397 V401 L402 V403 V416L395-K399 PolarHBondContact O-N 3.06Å; L396-K399 PolarHBondContact O-N 3.01Å; A397-K399 PolarHBondContact O-N 3.3Å; K399-V401 PolarHBondContact O-N 2.86Å; K399-L402 PolarHBondContact O-N 2.99Å; K399-V403 WeakPolarHBondContact O-CG2 3.48Å; K399-V403 PolarHBondContact O-N 3.02Å; K399-V403 VanDerWaalsContact O-N 3.1Å; K399-V416 HydrophobicContact CB-CG2 4.19Å
400K79.4Confident74.5Confident87 Ų8762.8 Ų62.838%0.37832%0.318SS..Hα-helixtrans-59-48-178.6-177.7169.4-177.2152.80111.7E333 F334 L396 A397 C398 L402 V403 I404E333-K400 PolarHBondContact O-NZ 3.24Å; F334-K400 HydrophobicContact CE1-CG 4.48Å; L396-K400 WeakPolarHBondContact O-CB 3.23Å; L396-K400 PolarHBondContact O-N 3.5Å; A397-K400 PolarHBondContact O-N 2.85Å; C398-K400 PolarHBondContact O-N 3.44Å; K400-L402 PolarHBondContact O-N 2.95Å; K400-V403 PolarHBondContact O-N 3.07Å; K400-I404 HydrophobicContact CG-CD1 4.23Å; K400-I404 WeakPolarHBondContact O-CG1 3.17Å; K400-I404 PolarHBondContact O-N 3.33Å
401V79.8Confident73.7Confident15 Ų1568.7 Ų68.79%0.09133%0.333CS..Hα-helixtrans-57-49.4177.51630000111A397 C398 K399 V403 I404 W405 L446 N450 W568A397-V401 WeakPolarHBondContact O-CG2 3.31Å; A397-V401 PolarHBondContact O-N 3.23Å; C398-V401 PolarHBondContact O-N 2.04Å; K399-V401 PolarHBondContact O-N 2.86Å; V401-V403 VanDerWaalsContact C-N 3.31Å; V401-V403 PolarHBondContact O-N 3.43Å; V401-I404 WeakPolarHBondContact O-CB 3.16Å; V401-I404 PolarHBondContact O-N 3.04Å; V401-I404 VanDerWaalsContact O-N 3.16Å; V401-W405 VanDerWaalsContact O-CD1 3.3Å; V401-W405 PolarHBondContact O-N 3.2Å; V401-L446 HydrophobicContact CG2-CD1 4.34Å; V401-L446 HydrophobicContact CG2-CG 4.46Å; V401-N450 HydrophobicContact CG1-CB 3.94Å; V401-N450 WeakPolarHBondContact CG1-ND2 3.49Å; V401-N450 VanDerWaalsContact CG1-OD1 3.26Å; V401-N450 WeakPolarHBondContact CG1-OD1 3.39Å; V401-N450 HydrophobicContact CG2-CB 4.22Å; V401-W568 HydrophobicContact CG1-CH2 3.58Å; V401-W568 HydrophobicContact CG1-CZ3 3.82Å
402L77Confident73.1Confident0 Ų069.8 Ų69.80%034%0.337CS..Hα-helixtrans-70-27.1-174.5-60.7172.1000113.6C398 K399 K400 I407 I412 N415 V416 C419 W568 L571C398-L402 VanDerWaalsContact O-CG 3.24Å; C398-L402 WeakPolarHBondContact O-CG 3.48Å; C398-L402 PolarHBondContact O-N 3.33Å; C398-L402 VanDerWaalsContact O-N 3.11Å; K399-L402 PolarHBondContact O-N 2.99Å; K400-L402 PolarHBondContact O-N 2.95Å; L402-I407 HydrophobicContact CB-CD1 3.97Å; L402-I407 HydrophobicContact CD2-CD1 3.28Å; L402-I407 HydrophobicContact CG-CD1 4.15Å; L402-I407 PolarHBondContact O-N 3.36Å; L402-I412 HydrophobicContact CB-CD1 3.56Å; L402-I412 HydrophobicContact CD1-CD1 4.41Å; L402-N415 HydrophobicContact CD1-CB 3.8Å; L402-N415 WeakPolarHBondContact CD1-O 3.43Å; L402-V416 HydrophobicContact CD1-CB 4.22Å; L402-V416 HydrophobicContact CD1-CG2 3.61Å; L402-V416 VanDerWaalsContact CD1-N 3.34Å; L402-C419 HydrophobicContact CD1-CB 4.47Å; L402-W568 HydrophobicContact CD2-CZ3 4.19Å; L402-L571 HydrophobicContact CD2-CD2 3.28Å; L402-L571 HydrophobicContact CD2-CG 4.12Å
403V71.3Confident72.7Confident56 Ų5675 Ų7534%0.33936%0.355SS..Hα-helixtrans-72.1-38.8172.4-179.20000111.5F334 K399 K400 V401 W405 K406F334-V403 HydrophobicContact CE1-CB 4.41Å; F334-V403 HydrophobicContact CE1-CG1 4.25Å; F334-V403 HydrophobicContact CE2-CG1 4.12Å; F334-V403 HydrophobicContact CZ-CB 3.92Å; F334-V403 HydrophobicContact CZ-CG1 3.39Å; K399-V403 WeakPolarHBondContact O-CG2 3.48Å; K399-V403 PolarHBondContact O-N 3.02Å; K399-V403 VanDerWaalsContact O-N 3.1Å; K400-V403 PolarHBondContact O-N 3.07Å; V401-V403 VanDerWaalsContact C-N 3.31Å; V401-V403 PolarHBondContact O-N 3.43Å; V403-W405 PolarHBondContact O-N 3.25Å; V403-K406 PolarHBondContact O-N 2.77Å
404I66.6Low72.5Confident52 Ų5276.7 Ų76.727%0.26736%0.359SS..Hα-helixtrans-57.2-39.8177.2-67.8165.6000110.9P247 F334 K400 V401 K406P247-I404 HydrophobicContact CB-CG2 4.07Å; F334-I404 HydrophobicContact CD1-CD1 4.48Å; F334-I404 HydrophobicContact CD1-CG1 3.87Å; F334-I404 HydrophobicContact CE1-CD1 4.48Å; F334-I404 HydrophobicContact CE1-CG1 3.65Å; K400-I404 HydrophobicContact CG-CD1 4.23Å; K400-I404 WeakPolarHBondContact O-CG1 3.17Å; K400-I404 PolarHBondContact O-N 3.33Å; V401-I404 WeakPolarHBondContact O-CB 3.16Å; V401-I404 PolarHBondContact O-N 3.04Å; V401-I404 VanDerWaalsContact O-N 3.16Å; I404-K406 PolarHBondContact O-N 2.65Å
405W63.6Low72.2Confident51 Ų5177.5 Ų77.519%0.19336%0.363CS..THydrogen-bonded Turntrans-77.25.3178.6-76.588.9000114.5L245 I354 V401 V403 I407 N450 P455 F572L245-W405 VanDerWaalsContact O-CH2 3.3Å; L245-W405 WeakPolarHBondContact O-CH2 3.27Å; L245-W405 WeakPolarHBondContact O-CZ2 3.46Å; I354-W405 HydrophobicContact CD1-CZ3 4.46Å; V401-W405 VanDerWaalsContact O-CD1 3.3Å; V401-W405 PolarHBondContact O-N 3.2Å; V403-W405 PolarHBondContact O-N 3.25Å; W405-I407 HydrophobicContact CB-CD1 4.47Å; W405-I407 HydrophobicContact CB-CG1 3.91Å; W405-I407 PolarHBondContact O-N 3.11Å; W405-N450 PolarHBondContact NE1-ND2 2.93Å; W405-N450 PolarHBondContact NE1-OD1 2.84Å; W405-P455 HydrophobicContact CZ2-CG 4.49Å; W405-F572 HydrophobicContact CB-CD1 4.11Å; W405-F572 HydrophobicContact CB-CE1 3.46Å; W405-F572 VanDerWaalsContact CB-CE1 3.46Å; W405-F572 HydrophobicContact CB-CZ 4.3Å; W405-F572 AromaticContact CD1-CE1 3.71Å; W405-F572 AromaticContact CD1-CZ 3.66Å; W405-F572 HydrophobicContact CD2-CD1 4.16Å; W405-F572 AromaticContact CD2-CE1 3.5Å; W405-F572 HydrophobicContact CD2-CE1 3.5Å; W405-F572 VanDerWaalsContact CD2-CE1 3.5Å; W405-F572 HydrophobicContact CD2-CE2 4.29Å; W405-F572 AromaticContact CD2-CZ 3.59Å; W405-F572 HydrophobicContact CD2-CZ 3.59Å; W405-F572 AromaticContact CE2-CZ 3.69Å; W405-F572 HydrophobicContact CE3-CD1 4.19Å; W405-F572 AromaticContact CE3-CE1 3.99Å; W405-F572 HydrophobicContact CE3-CE1 3.99Å; W405-F572 HydrophobicContact CE3-CZ 4.23Å; W405-F572 HydrophobicContact CG-CD1 4.14Å; W405-F572 AromaticContact CG-CE1 3.24Å; W405-F572 HydrophobicContact CG-CE1 3.24Å; W405-F572 AromaticContact CG-CZ 3.59Å; W405-F572 HydrophobicContact CG-CZ 3.59Å; W405-F572 HydrophobicContact CZ2-CZ 4.39Å; W405-F572 AromaticContact NE1-CZ 3.75Å
406K60.4Low72Confident163 Ų16377.6 Ų77.671%0.70936%0.364SS*.THydrogen-bonded Turntrans4834.9-178.3-61.5-175.2177.1-178.50113.2V403 I404 R408V403-K406 PolarHBondContact O-N 2.77Å; I404-K406 PolarHBondContact O-N 2.65Å; K406-R408 PolarHBondContact O-N 3.03Å; K406-R408 VanDerWaalsContact O-N 3.12Å
407I53.2Low72.2Confident29 Ų2975.8 Ų75.815%0.14935%0.353CS..  trans-57.2124.2-174.9-62.8-176.3000109.1L402 W405 F409 N415 F572L402-I407 HydrophobicContact CB-CD1 3.97Å; L402-I407 HydrophobicContact CD2-CD1 3.28Å; L402-I407 HydrophobicContact CG-CD1 4.15Å; L402-I407 PolarHBondContact O-N 3.36Å; W405-I407 HydrophobicContact CB-CD1 4.47Å; W405-I407 HydrophobicContact CB-CG1 3.91Å; W405-I407 PolarHBondContact O-N 3.11Å; I407-F409 PolarHBondContact O-N 3.02Å; I407-N415 WeakPolarHBondContact CG2-ND2 3.33Å; I407-F572 HydrophobicContact CD1-CD1 3.7Å; I407-F572 HydrophobicContact CD1-CE1 3.66Å; I407-F572 HydrophobicContact CG1-CD1 4Å; I407-F572 HydrophobicContact CG1-CE1 4.13Å
408R46.1Very low72.2Confident199 Ų19977.3 Ų77.375%0.75136%0.358SS*.  trans-44.6132.3-174.1-75.3-160-94.6-169.1-5.2111K406 G410K406-R408 PolarHBondContact O-N 3.03Å; K406-R408 VanDerWaalsContact O-N 3.12Å; R408-G410 PolarHBondContact O-N 2.92Å
409F47.9Very low72.3Confident208 Ų20877.3 Ų77.391%0.91236%0.358SS*.THydrogen-bonded Turntrans-50.1-8.5-173-74.2-84.6000116.7I407I407-F409 PolarHBondContact O-N 3.02Å
410G53.4Low72.6Confident73 Ų7372.7 Ų72.775%0.75334%0.338SS*.THydrogen-bonded Turntrans-73.8-25.3-17700000116R408R408-G410 PolarHBondContact O-N 2.92Å
411R69.9Low73.1Confident188 Ų18870.8 Ų70.871%0.70933%0.33SS*.SBendtrans-136.813.4-173-65-171.3-176.51792.5116R413 Q414 N415R411-R413 VanDerWaalsContact C-N 3.26Å; R411-R413 PolarHBondContact O-N 2.9Å; R411-R413 VanDerWaalsContact O-N 3.1Å; R411-Q414 PolarHBondContact O-N 3.38Å; R411-N415 PolarHBondContact O-N 3.17Å; R411-N415 PolarHBondContact O-OD1 3.11Å
412I73.2Confident73.6Confident55 Ų5571.8 Ų71.828%0.28233%0.333SS..Hα-helixtrans-52.3-41.9-174.7-169.261.2000113.2L402 Q414 N415 V416L402-I412 HydrophobicContact CB-CD1 3.56Å; L402-I412 HydrophobicContact CD1-CD1 4.41Å; I412-Q414 PolarHBondContact O-N 2.89Å; I412-N415 PolarHBondContact O-N 3.5Å; I412-V416 HydrophobicContact CD1-CG2 4.43Å; I412-V416 HydrophobicContact CG1-CG2 4.47Å; I412-V416 WeakPolarHBondContact O-CB 3.47Å; I412-V416 WeakPolarHBondContact O-CG2 3.37Å; I412-V416 PolarHBondContact O-N 2.92Å
413R78.6Confident74.3Confident132 Ų13271.8 Ų71.850%0.49833%0.333SS..Hα-helixtrans-64.2-41.9179.5-171.5177.4-178.6119.23.3112.2R411 K417 F613 E617R411-R413 VanDerWaalsContact C-N 3.26Å; R411-R413 PolarHBondContact O-N 2.9Å; R411-R413 VanDerWaalsContact O-N 3.1Å; R413-K417 WeakPolarHBondContact O-CG 3.32Å; R413-K417 PolarHBondContact O-N 2.97Å; R413-F613 HydrophobicContact CG-CE1 4.17Å; R413-E617 IonicContact CZ-OE1 3.18Å; R413-E617 IonicContact NH1-OE1 2.75Å; R413-E617 PolarHBondContact NH1-OE1 3.12Å; R413-E617 IonicContact NH2-OE1 2.72Å; R413-E617 PolarHBondContact NH2-OE1 2.78Å
414Q82.1Confident75.2Confident89 Ų8969.1 Ų69.142%0.41632%0.317SS..Hα-helixtrans-72.1-43.5178.6-171.558.340.700110.7R411 I412 V416 K417 D418R411-Q414 PolarHBondContact O-N 3.38Å; I412-Q414 PolarHBondContact O-N 2.89Å; Q414-V416 VanDerWaalsContact C-N 3.27Å; Q414-V416 PolarHBondContact O-N 3.48Å; Q414-K417 CarbonylContact O-C 3.58Å; Q414-K417 WeakPolarHBondContact O-CA 2.97Å; Q414-K417 WeakPolarHBondContact O-CB 3.43Å; Q414-K417 PolarHBondContact O-N 2.95Å; Q414-D418 PolarHBondContact NE2-OD1 3.32Å; Q414-D418 VanDerWaalsContact O-CG 3.3Å; Q414-D418 PolarHBondContact O-N 3.36Å
415N82.8Confident76.2Confident16 Ų1670.5 Ų70.59%0.08633%0.325CS..Hα-helixtrans-60.8-37.2178.3-69.819.5000112L402 I407 R411 I412 D418 C419 L571L402-N415 HydrophobicContact CD1-CB 3.8Å; L402-N415 WeakPolarHBondContact CD1-O 3.43Å; I407-N415 WeakPolarHBondContact CG2-ND2 3.33Å; R411-N415 PolarHBondContact O-N 3.17Å; R411-N415 PolarHBondContact O-OD1 3.11Å; I412-N415 PolarHBondContact O-N 3.5Å; N415-D418 PolarHBondContact O-N 3.43Å; N415-C419 VanDerWaalsContact O-CB 3.29Å; N415-C419 WeakPolarHBondContact O-CB 3.36Å; N415-C419 PolarHBondContact O-N 2.85Å; N415-L571 HydrophobicContact CB-CD1 3.66Å; N415-L571 HydrophobicContact CB-CG 4.34Å; N415-L571 PolarHBondContact ND2-O 3.48Å
416V85.2Confident77.3Confident10 Ų1068.9 Ų68.96%0.06132%0.319CS..Hα-helixtrans-62.7-42.1172.6170.40000111.1L395 K399 L402 I412 Q414 F420 F613L395-V416 HydrophobicContact CD1-CG1 3.51Å; L395-V416 HydrophobicContact CG-CG1 4.32Å; K399-V416 HydrophobicContact CB-CG2 4.19Å; L402-V416 HydrophobicContact CD1-CB 4.22Å; L402-V416 HydrophobicContact CD1-CG2 3.61Å; L402-V416 VanDerWaalsContact CD1-N 3.34Å; I412-V416 HydrophobicContact CD1-CG2 4.43Å; I412-V416 HydrophobicContact CG1-CG2 4.47Å; I412-V416 WeakPolarHBondContact O-CB 3.47Å; I412-V416 WeakPolarHBondContact O-CG2 3.37Å; I412-V416 PolarHBondContact O-N 2.92Å; Q414-V416 VanDerWaalsContact C-N 3.27Å; Q414-V416 PolarHBondContact O-N 3.48Å; V416-F420 WeakPolarHBondContact O-CB 3.28Å; V416-F420 PolarHBondContact O-N 3.39Å; V416-F613 HydrophobicContact CG1-CZ 4.02Å
417K87.2Confident78.6Confident49 Ų4961.1 Ų61.121%0.21329%0.285CS..Hα-helixtrans-65.1-44.8176.7-71.3-179.2173.4-165.70111.9R413 Q414 F420 K421 L609 F613R413-K417 WeakPolarHBondContact O-CG 3.32Å; R413-K417 PolarHBondContact O-N 2.97Å; Q414-K417 CarbonylContact O-C 3.58Å; Q414-K417 WeakPolarHBondContact O-CA 2.97Å; Q414-K417 WeakPolarHBondContact O-CB 3.43Å; Q414-K417 PolarHBondContact O-N 2.95Å; K417-F420 PolarHBondContact O-N 2.97Å; K417-K421 WeakPolarHBondContact O-CG 3.3Å; K417-K421 PolarHBondContact O-N 3.27Å; K417-L609 HydrophobicContact CB-CD2 4.02Å; K417-L609 HydrophobicContact CD-CD2 4.41Å; K417-L609 HydrophobicContact CG-CD2 3.98Å; K417-F613 HydrophobicContact CD-CE2 4.42Å; K417-F613 HydrophobicContact CD-CZ 4.42Å; K417-F613 HydrophobicContact CG-CD2 4.44Å; K417-F613 HydrophobicContact CG-CE2 3.49Å; K417-F613 VanDerWaalsContact CG-CE2 3.49Å; K417-F613 HydrophobicContact CG-CZ 3.54Å
418D86.9Confident80Confident54 Ų5461.4 Ų61.429%0.28929%0.285SS..Hα-helixtrans-65.6-42.1-179.3-61.9-19.2000110.7Q414 N415 F420 K421 E422 F567Q414-D418 PolarHBondContact NE2-OD1 3.32Å; Q414-D418 VanDerWaalsContact O-CG 3.3Å; Q414-D418 PolarHBondContact O-N 3.36Å; N415-D418 PolarHBondContact O-N 3.43Å; D418-F420 PolarHBondContact O-N 3.2Å; D418-K421 PolarHBondContact O-N 3.49Å; D418-E422 WeakPolarHBondContact O-CB 3.34Å; D418-E422 PolarHBondContact O-N 3.49Å; D418-F567 HydrophobicContact CB-CE2 4.43Å
419C89.2Confident81.8Confident0 Ų057.5 Ų57.50%028%0.276CS..Hα-helixtrans-57.3-48.8170176.40000111.5C398 L402 N415 K421 E422 Y423 F567C398-C419 VanDerWaalsContact CA-SG 3.57Å; C398-C419 HydrophobicContact CB-CB 3.73Å; C398-C419 WeakPolarHBondContact CB-SG 2.89Å; C398-C419 WeakPolarHBondContact SG-CB 3.5Å; C398-C419 CovalentContact SG-SG 2.05Å; C398-C419 PolarHBondContact SG-SG 2.99Å; L402-C419 HydrophobicContact CD1-CB 4.47Å; N415-C419 VanDerWaalsContact O-CB 3.29Å; N415-C419 WeakPolarHBondContact O-CB 3.36Å; N415-C419 PolarHBondContact O-N 2.85Å; C419-K421 PolarHBondContact O-N 3.29Å; C419-E422 PolarHBondContact O-N 3.45Å; C419-Y423 WeakPolarHBondContact O-CD2 3.5Å; C419-Y423 PolarHBondContact O-N 3.46Å; C419-Y423 VanDerWaalsContact O-N 3.1Å; C419-F567 HydrophobicContact CB-CE1 4.4Å; C419-F567 HydrophobicContact CB-CZ 4.03Å
420F90.9Very high83.4Confident0 Ų050.3 Ų50.30%025%0.251CS..Hα-helixtrans-59.9-46.6179-178.9-84.1000111.8P391 L394 L395 C398 V416 K417 D418 E422 Y423 A424 W439 I605 I608 L609 I612P391-F420 HydrophobicContact CB-CE2 4.29Å; P391-F420 HydrophobicContact CB-CZ 4.18Å; P391-F420 WeakPolarHBondContact O-CE2 3.14Å; L394-F420 HydrophobicContact CB-CD2 4.31Å; L394-F420 HydrophobicContact CB-CE2 4.19Å; L394-F420 HydrophobicContact CD2-CD2 4Å; L394-F420 HydrophobicContact CD2-CE2 4Å; L394-F420 HydrophobicContact CG-CD2 3.98Å; L394-F420 HydrophobicContact CG-CE2 4.21Å; L395-F420 HydrophobicContact CB-CD2 4Å; L395-F420 HydrophobicContact CB-CE2 4.38Å; L395-F420 HydrophobicContact CD1-CB 4.2Å; L395-F420 HydrophobicContact CD1-CD2 4.12Å; L395-F420 HydrophobicContact CD1-CG 4.37Å; C398-F420 PolarHBondContact SG-N 2.98Å; C398-F420 VanDerWaalsContact SG-N 3.44Å; V416-F420 WeakPolarHBondContact O-CB 3.28Å; V416-F420 PolarHBondContact O-N 3.39Å; K417-F420 PolarHBondContact O-N 2.97Å; D418-F420 PolarHBondContact O-N 3.2Å; F420-E422 PolarHBondContact O-N 3.28Å; F420-Y423 PolarHBondContact O-N 3.35Å; F420-A424 HydrophobicContact CD1-CB 4.18Å; F420-A424 HydrophobicContact CE1-CB 3.92Å; F420-A424 HydrophobicContact CZ-CB 4.4Å; F420-A424 WeakPolarHBondContact O-CB 3.35Å; F420-A424 PolarHBondContact O-N 2.73Å; F420-W439 HydrophobicContact CZ-CH2 4.35Å; F420-W439 HydrophobicContact CZ-CZ3 4.23Å; F420-I605 HydrophobicContact CD1-CG2 4.38Å; F420-I605 HydrophobicContact CE1-CG2 4.21Å; F420-I608 HydrophobicContact CE1-CG2 4.27Å; F420-I608 HydrophobicContact CZ-CG2 3.88Å; F420-L609 HydrophobicContact CB-CD1 3.9Å; F420-L609 HydrophobicContact CD1-CB 4.24Å; F420-L609 HydrophobicContact CD1-CD1 3.43Å; F420-L609 VanDerWaalsContact CD1-CD1 3.43Å; F420-L609 HydrophobicContact CD1-CG 4.28Å; F420-L609 HydrophobicContact CD2-CD1 4.3Å; F420-L609 HydrophobicContact CE1-CB 4.16Å; F420-L609 HydrophobicContact CE1-CD1 3.96Å; F420-L609 HydrophobicContact CG-CD1 3.59Å; F420-I612 HydrophobicContact CE2-CD1 4.11Å; F420-I612 HydrophobicContact CZ-CD1 3.84Å
421K90.6Very high84.7Confident48 Ų4848 Ų4821%0.20922%0.224CC..Hα-helixtrans-58.6-48.5179.8-74.9-175.7171.7-1620111.5K417 D418 C419 Y423 A424 L425 E602 I605 L609K417-K421 WeakPolarHBondContact O-CG 3.3Å; K417-K421 PolarHBondContact O-N 3.27Å; D418-K421 PolarHBondContact O-N 3.49Å; C419-K421 PolarHBondContact O-N 3.29Å; K421-Y423 PolarHBondContact O-N 3.21Å; K421-A424 PolarHBondContact O-N 2.83Å; K421-L425 WeakPolarHBondContact O-CG 3.46Å; K421-L425 PolarHBondContact O-N 3.42Å; K421-E602 IonicContact NZ-OE1 3.57Å; K421-I605 HydrophobicContact CB-CG2 4.42Å; K421-I605 HydrophobicContact CG-CG2 4.05Å; K421-L609 HydrophobicContact CG-CD2 4.27Å
422E89.5Confident85Confident36 Ų3644.7 Ų44.717%0.16823%0.229CC..Hα-helixtrans-56.9-50.3178.8-179.260.6-14700111.5D418 C419 F420 L425 K426 F567D418-E422 WeakPolarHBondContact O-CB 3.34Å; D418-E422 PolarHBondContact O-N 3.49Å; C419-E422 PolarHBondContact O-N 3.45Å; F420-E422 PolarHBondContact O-N 3.28Å; E422-L425 PolarHBondContact O-N 2.93Å; E422-K426 WeakPolarHBondContact O-CG 3.39Å; E422-K426 PolarHBondContact O-N 3.31Å; E422-K426 VanDerWaalsContact OE1-CE 3.24Å; E422-K426 WeakPolarHBondContact OE1-CE 3.25Å; E422-F567 HydrophobicContact CB-CD2 4.06Å; E422-F567 HydrophobicContact CB-CE2 3.99Å; E422-F567 HydrophobicContact CB-CZ 4.35Å; E422-F567 HydrophobicContact CG-CB 4.33Å; E422-F567 HydrophobicContact CG-CD1 4.31Å; E422-F567 HydrophobicContact CG-CD2 3.85Å; E422-F567 HydrophobicContact CG-CE2 4.26Å; E422-F567 HydrophobicContact CG-CG 3.89Å
423Y91Very high85.2Confident0 Ų044 Ų440%023%0.229CC..Hα-helixtrans-79.5-23-177.7-75.1-86.7000113.9C419 F420 K421 K426 A427 A442 Q445 L446 D449 F567 W568C419-Y423 WeakPolarHBondContact O-CD2 3.5Å; C419-Y423 PolarHBondContact O-N 3.46Å; C419-Y423 VanDerWaalsContact O-N 3.1Å; F420-Y423 PolarHBondContact O-N 3.35Å; K421-Y423 PolarHBondContact O-N 3.21Å; Y423-K426 HydrophobicContact CD1-CD 3.9Å; Y423-K426 HydrophobicContact CE1-CD 4Å; Y423-K426 PolarHBondContact O-N 3.46Å; Y423-A427 WeakPolarHBondContact O-CB 3.49Å; Y423-A427 PolarHBondContact O-N 2.89Å; Y423-A442 WeakPolarHBondContact CD1-O 3.24Å; Y423-A442 VanDerWaalsContact O-CB 3.27Å; Y423-A442 WeakPolarHBondContact O-CB 3.41Å; Y423-Q445 HydrophobicContact CD1-CB 4.41Å; Y423-Q445 HydrophobicContact CE1-CB 4.21Å; Y423-Q445 HydrophobicContact CE1-CG 4.08Å; Y423-L446 HydrophobicContact CD1-CB 3.71Å; Y423-L446 HydrophobicContact CD2-CB 4.39Å; Y423-L446 HydrophobicContact CD2-CD1 4Å; Y423-L446 HydrophobicContact CE1-CB 3.63Å; Y423-L446 HydrophobicContact CE1-CD1 4.31Å; Y423-L446 VanDerWaalsContact CE1-N 3.27Å; Y423-L446 HydrophobicContact CE2-CB 4.33Å; Y423-L446 HydrophobicContact CE2-CD1 3.55Å; Y423-L446 HydrophobicContact CE2-CG 4.49Å; Y423-L446 HydrophobicContact CG-CB 4.11Å; Y423-D449 WeakPolarHBondContact OH-CB 3.4Å; Y423-D449 PolarHBondContact OH-OD2 3.05Å; Y423-F567 HydrophobicContact CE2-CE1 4.37Å; Y423-W568 AromaticContact CE2-CZ2 3.97Å; Y423-W568 HydrophobicContact CE2-CZ2 3.97Å; Y423-W568 VanDerWaalsContact OH-CZ2 3.28Å; Y423-W568 WeakPolarHBondContact OH-CZ2 3.5Å; Y423-W568 PolarHBondContact OH-NE1 2.75Å
424A89.9Confident84.7Confident0 Ų042.1 Ų42.10%024%0.235CC..Hα-helixtrans-67.6-38.7170.200000111.3F420 K421 K426 A427 R428 F437 W439 I605F420-A424 HydrophobicContact CD1-CB 4.18Å; F420-A424 HydrophobicContact CE1-CB 3.92Å; F420-A424 HydrophobicContact CZ-CB 4.4Å; F420-A424 WeakPolarHBondContact O-CB 3.35Å; F420-A424 PolarHBondContact O-N 2.73Å; K421-A424 PolarHBondContact O-N 2.83Å; A424-K426 VanDerWaalsContact C-N 3.34Å; A424-A427 WeakPolarHBondContact O-CB 3.41Å; A424-A427 PolarHBondContact O-N 2.84Å; A424-R428 PolarHBondContact O-N 3.49Å; A424-F437 WeakPolarHBondContact O-CD1 3.4Å; A424-W439 HydrophobicContact CB-CH2 4.2Å; A424-W439 HydrophobicContact CB-CZ3 3.86Å; A424-I605 HydrophobicContact CB-CD1 4.08Å; A424-I605 HydrophobicContact CB-CG1 4.25Å; A424-I605 HydrophobicContact CB-CG2 3.87Å
425L87.7Confident84.3Confident80 Ų8043.7 Ų43.742%0.41925%0.246SC..Hα-helixtrans-60.7-44.8170.7-71.4167.4000110.8K421 E422 A427 R428 M429 I605K421-L425 WeakPolarHBondContact O-CG 3.46Å; K421-L425 PolarHBondContact O-N 3.42Å; E422-L425 PolarHBondContact O-N 2.93Å; L425-A427 VanDerWaalsContact C-N 3.33Å; L425-A427 PolarHBondContact O-N 3.23Å; L425-R428 WeakPolarHBondContact O-CB 3.5Å; L425-R428 PolarHBondContact O-N 2.92Å; L425-M429 WeakPolarHBondContact O-CG 3.24Å; L425-M429 PolarHBondContact O-N 2.89Å; L425-I605 HydrophobicContact CB-CD1 4.43Å; L425-I605 HydrophobicContact CD2-CD1 3.39Å; L425-I605 HydrophobicContact CG-CD1 3.56Å
426K88.1Confident84.2Confident17 Ų1748 Ų487%0.07427%0.266CS..Hα-helixtrans-62.1-37.5174.2-63.3-177.7-172.1-164.60112.7E422 Y423 A424 R428 M429 S430 Q445 D449E422-K426 WeakPolarHBondContact O-CG 3.39Å; E422-K426 PolarHBondContact O-N 3.31Å; E422-K426 VanDerWaalsContact OE1-CE 3.24Å; E422-K426 WeakPolarHBondContact OE1-CE 3.25Å; Y423-K426 HydrophobicContact CD1-CD 3.9Å; Y423-K426 HydrophobicContact CE1-CD 4Å; Y423-K426 PolarHBondContact O-N 3.46Å; A424-K426 VanDerWaalsContact C-N 3.34Å; K426-R428 VanDerWaalsContact C-N 3.33Å; K426-R428 PolarHBondContact O-N 2.99Å; K426-M429 HydrophobicContact CG-CE 4.19Å; K426-M429 PolarHBondContact O-N 3.04Å; K426-S430 WeakPolarHBondContact O-CB 3.44Å; K426-S430 PolarHBondContact O-N 2.91Å; K426-S430 PolarHBondContact O-OG 3.5Å; K426-Q445 HydrophobicContact CD-CG 4.25Å; K426-D449 IonicContact NZ-OD2 2.9Å; K426-D449 PolarHBondContact NZ-OD2 2.79Å
427A87.2Confident84.1Confident0 Ų049.3 Ų49.30%027%0.272CS..Hα-helixtrans-62-40.917500000111.7Y423 A424 L425 S430 S431 F437 N438 W439 A442Y423-A427 WeakPolarHBondContact O-CB 3.49Å; Y423-A427 PolarHBondContact O-N 2.89Å; A424-A427 WeakPolarHBondContact O-CB 3.41Å; A424-A427 PolarHBondContact O-N 2.84Å; L425-A427 VanDerWaalsContact C-N 3.33Å; L425-A427 PolarHBondContact O-N 3.23Å; A427-S430 PolarHBondContact O-OG 3.35Å; A427-S431 PolarHBondContact O-N 3.18Å; A427-F437 HydrophobicContact CB-CB 4.16Å; A427-F437 HydrophobicContact CB-CD1 4.05Å; A427-N438 PolarHBondContact O-N 3.4Å; A427-W439 HydrophobicContact CB-CD2 4.49Å; A427-W439 HydrophobicContact CB-CE3 3.89Å; A427-W439 HydrophobicContact CB-CZ3 4.1Å; A427-A442 HydrophobicContact CB-CB 3.58Å
428R83.1Confident84.2Confident36 Ų3650 Ų5014%0.13628%0.278CS..Hα-helixtrans-66.6-47.6176.9-164.282.8171-167.2-5.6111.2A424 L425 K426 S430 S431 P434 D435 F437A424-R428 PolarHBondContact O-N 3.49Å; L425-R428 WeakPolarHBondContact O-CB 3.5Å; L425-R428 PolarHBondContact O-N 2.92Å; K426-R428 VanDerWaalsContact C-N 3.33Å; K426-R428 PolarHBondContact O-N 2.99Å; R428-S430 VanDerWaalsContact C-N 3.27Å; R428-S430 PolarHBondContact O-N 3.29Å; R428-S431 VanDerWaalsContact O-CB 3.29Å; R428-S431 WeakPolarHBondContact O-CB 3.49Å; R428-S431 PolarHBondContact O-N 3.12Å; R428-P434 PolarHBondContact NE-O 3.35Å; R428-P434 PolarHBondContact NH2-O 2.9Å; R428-D435 PolarHBondContact NH1-O 3.2Å; R428-D435 IonicContact NH2-OD1 3.23Å; R428-D435 PolarHBondContact NH2-OD1 3.47Å; R428-F437 HydrophobicContact CB-CD1 3.93Å; R428-F437 HydrophobicContact CB-CE1 3.9Å; R428-F437 HydrophobicContact CG-CE1 4.33Å
429M83.5Confident84.2Confident117 Ų11749 Ų4958%0.57627%0.27SS*.Hα-helixtrans-65.9-26.6-179.2-69.1-173.3-6800113.9L425 K426 S431L425-M429 WeakPolarHBondContact O-CG 3.24Å; L425-M429 PolarHBondContact O-N 2.89Å; K426-M429 HydrophobicContact CG-CE 4.19Å; K426-M429 PolarHBondContact O-N 3.04Å; M429-S431 VanDerWaalsContact C-N 3.33Å
430S82.3Confident84.2Confident56 Ų5651 Ų5139%0.39228%0.284SS..THydrogen-bonded Turntrans-903.3178.155.30000113.8K426 A427 R428 N438K426-S430 WeakPolarHBondContact O-CB 3.44Å; K426-S430 PolarHBondContact O-N 2.91Å; K426-S430 PolarHBondContact O-OG 3.5Å; A427-S430 PolarHBondContact O-OG 3.35Å; R428-S430 VanDerWaalsContact C-N 3.27Å; R428-S430 PolarHBondContact O-N 3.29Å; S430-N438 PolarHBondContact O-ND2 2.88Å
431S79.4Confident83.9Confident24 Ų2452.6 Ų52.617%0.16830%0.297CS..SBendtrans-85.2147.7176.61760000111.6A427 R428 M429 S433 M436A427-S431 PolarHBondContact O-N 3.18Å; R428-S431 VanDerWaalsContact O-CB 3.29Å; R428-S431 WeakPolarHBondContact O-CB 3.49Å; R428-S431 PolarHBondContact O-N 3.12Å; M429-S431 VanDerWaalsContact C-N 3.33Å; S431-S433 VanDerWaalsContact C-N 3.26Å; S431-S433 WeakPolarHBondContact CB-O 3.33Å; S431-S433 PolarHBondContact O-N 3.14Å; S431-S433 PolarHBondContact OG-N 3.21Å; S431-S433 PolarHBondContact OG-O 3.49Å; S431-M436 WeakPolarHBondContact CB-O 3.49Å; S431-M436 VanDerWaalsContact OG-CB 3.28Å; S431-M436 WeakPolarHBondContact OG-CB 3.42Å; S431-M436 PolarHBondContact OG-O 3.33Å; S431-M436 VanDerWaalsContact OG-O 3.13Å
432S77.3Confident83.8Confident119 Ų11950.3 Ų50.383%0.83229%0.287SS*.SBendtrans-73.5-18.3173.959.30000113.6
433S76.1Confident83.8Confident40 Ų4049.6 Ų49.628%0.2829%0.285SS..SBendtrans-121.6136.5178174.90000110S431 D435 M436S431-S433 VanDerWaalsContact C-N 3.26Å; S431-S433 WeakPolarHBondContact CB-O 3.33Å; S431-S433 PolarHBondContact O-N 3.14Å; S431-S433 PolarHBondContact OG-N 3.21Å; S431-S433 PolarHBondContact OG-O 3.49Å; S433-D435 PolarHBondContact O-N 2.82Å; S433-D435 PolarHBondContact OG-N 2.79Å; S433-M436 PolarHBondContact O-N 2.97Å; S433-M436 VanDerWaalsContact O-N 3.13Å
434P69.6Low83.6Confident94 Ų9450.9 Ų50.961%0.6129%0.293SS*.THydrogen-bonded Turntrans-62.7-12179.325.5-33.7000113.5R428R428-P434 PolarHBondContact NE-O 3.35Å; R428-P434 PolarHBondContact NH2-O 2.9Å
435D72.1Confident83.6Confident122 Ų12253.8 Ų53.865%0.65231%0.306SS*.THydrogen-bonded Turntrans-102.5-1.9178.2-69.9-37.2000115.5R428 S433R428-D435 PolarHBondContact NH1-O 3.2Å; R428-D435 IonicContact NH2-OD1 3.23Å; R428-D435 PolarHBondContact NH2-OD1 3.47Å; S433-D435 PolarHBondContact O-N 2.82Å; S433-D435 PolarHBondContact OG-N 2.79Å
436M80.9Confident83.6Confident105 Ų10550 Ų5052%0.51729%0.286SS..  trans-111.6155.6-178.7-65.1-161.7-5200112S431 S433S431-M436 WeakPolarHBondContact CB-O 3.49Å; S431-M436 VanDerWaalsContact OG-CB 3.28Å; S431-M436 WeakPolarHBondContact OG-CB 3.42Å; S431-M436 PolarHBondContact OG-O 3.33Å; S431-M436 VanDerWaalsContact OG-O 3.13Å; S433-M436 PolarHBondContact O-N 2.97Å; S433-M436 VanDerWaalsContact O-N 3.13Å
437F84.1Confident83.6Confident39 Ų3954 Ų5417%0.17130%0.301CS..  trans-115126.9174.6-68.4-95.2000109.6A424 A427 R428 W439 I605 I608A424-F437 WeakPolarHBondContact O-CD1 3.4Å; A427-F437 HydrophobicContact CB-CB 4.16Å; A427-F437 HydrophobicContact CB-CD1 4.05Å; R428-F437 HydrophobicContact CB-CD1 3.93Å; R428-F437 HydrophobicContact CB-CE1 3.9Å; R428-F437 HydrophobicContact CG-CE1 4.33Å; F437-W439 VanDerWaalsContact C-N 3.34Å; F437-W439 HydrophobicContact CB-CD2 3.78Å; F437-W439 HydrophobicContact CB-CE3 4.31Å; F437-W439 HydrophobicContact CB-CG 4.32Å; F437-W439 HydrophobicContact CB-CH2 3.89Å; F437-W439 HydrophobicContact CB-CZ2 3.29Å; F437-W439 HydrophobicContact CB-CZ3 4.36Å; F437-W439 AromaticContact CD1-CH2 3.43Å; F437-W439 HydrophobicContact CD1-CH2 3.43Å; F437-W439 VanDerWaalsContact CD1-CH2 3.43Å; F437-W439 AromaticContact CD1-CZ2 3.65Å; F437-W439 HydrophobicContact CD1-CZ2 3.65Å; F437-W439 HydrophobicContact CD1-CZ3 4.03Å; F437-W439 HydrophobicContact CD2-CH2 4.19Å; F437-W439 AromaticContact CD2-CZ2 3.61Å; F437-W439 HydrophobicContact CD2-CZ2 3.61Å; F437-W439 AromaticContact CE1-CH2 3.89Å; F437-W439 HydrophobicContact CE1-CH2 3.89Å; F437-W439 HydrophobicContact CE1-CZ2 4.3Å; F437-W439 HydrophobicContact CE2-CZ2 4.27Å; F437-W439 AromaticContact CG-CE2 3.8Å; F437-W439 AromaticContact CG-CH2 3.59Å; F437-W439 HydrophobicContact CG-CH2 3.59Å; F437-W439 AromaticContact CG-CZ2 3.25Å; F437-W439 HydrophobicContact CG-CZ2 3.25Å; F437-W439 HydrophobicContact CG-CZ3 4.38Å; F437-W439 HydrophobicContact CZ-CH2 4.44Å; F437-W439 PolarHBondContact O-N 3.03Å; F437-I605 HydrophobicContact CE1-CG1 4.18Å; F437-I605 HydrophobicContact CZ-CG1 4.28Å; F437-I608 HydrophobicContact CD2-CD1 4.38Å; F437-I608 HydrophobicContact CE2-CD1 3.6Å; F437-I608 HydrophobicContact CZ-CD1 3.75Å
438N88.7Confident83.8Confident63 Ų6354.3 Ų54.334%0.33730%0.303SS..  trans-88.175.4170.8-168.7-13.2000110.2A427 S430 S440 A441 A442A427-N438 PolarHBondContact O-N 3.4Å; S430-N438 PolarHBondContact O-ND2 2.88Å; N438-S440 VanDerWaalsContact C-N 3.28Å; N438-S440 PolarHBondContact O-N 2.78Å; N438-A441 HydrophobicContact CB-CB 4.09Å; N438-A441 WeakPolarHBondContact ND2-CB 3.35Å; N438-A441 PolarHBondContact O-N 3.24Å; N438-A441 WeakPolarHBondContact OD1-CB 3.4Å; N438-A441 PolarHBondContact OD1-N 3.37Å; N438-A441 VanDerWaalsContact OD1-N 3.14Å; N438-A442 PolarHBondContact O-N 2.81Å; N438-A442 VanDerWaalsContact O-N 3.1Å
439W88.1Confident84.1Confident34 Ų3452.6 Ų52.613%0.12930%0.296CS..Hα-helixtrans-59.2-36.9-177.9-60.1118.1000113.1A389 P391 L394 F420 A424 A427 F437 A442 V443 I608A389-W439 HydrophobicContact CB-CB 3.93Å; A389-W439 WeakPolarHBondContact O-CB 3.04Å; P391-W439 HydrophobicContact CB-CH2 4.44Å; P391-W439 HydrophobicContact CB-CZ2 4.29Å; P391-W439 HydrophobicContact CG-CD2 4.18Å; P391-W439 HydrophobicContact CG-CH2 4.22Å; P391-W439 HydrophobicContact CG-CZ2 3.6Å; L394-W439 HydrophobicContact CD2-CE3 3.91Å; L394-W439 HydrophobicContact CD2-CZ3 3.9Å; F420-W439 HydrophobicContact CZ-CH2 4.35Å; F420-W439 HydrophobicContact CZ-CZ3 4.23Å; A424-W439 HydrophobicContact CB-CH2 4.2Å; A424-W439 HydrophobicContact CB-CZ3 3.86Å; A427-W439 HydrophobicContact CB-CD2 4.49Å; A427-W439 HydrophobicContact CB-CE3 3.89Å; A427-W439 HydrophobicContact CB-CZ3 4.1Å; F437-W439 VanDerWaalsContact C-N 3.34Å; F437-W439 HydrophobicContact CB-CD2 3.78Å; F437-W439 HydrophobicContact CB-CE3 4.31Å; F437-W439 HydrophobicContact CB-CG 4.32Å; F437-W439 HydrophobicContact CB-CH2 3.89Å; F437-W439 HydrophobicContact CB-CZ2 3.29Å; F437-W439 HydrophobicContact CB-CZ3 4.36Å; F437-W439 AromaticContact CD1-CH2 3.43Å; F437-W439 HydrophobicContact CD1-CH2 3.43Å; F437-W439 VanDerWaalsContact CD1-CH2 3.43Å; F437-W439 AromaticContact CD1-CZ2 3.65Å; F437-W439 HydrophobicContact CD1-CZ2 3.65Å; F437-W439 HydrophobicContact CD1-CZ3 4.03Å; F437-W439 HydrophobicContact CD2-CH2 4.19Å; F437-W439 AromaticContact CD2-CZ2 3.61Å; F437-W439 HydrophobicContact CD2-CZ2 3.61Å; F437-W439 AromaticContact CE1-CH2 3.89Å; F437-W439 HydrophobicContact CE1-CH2 3.89Å; F437-W439 HydrophobicContact CE1-CZ2 4.3Å; F437-W439 HydrophobicContact CE2-CZ2 4.27Å; F437-W439 AromaticContact CG-CE2 3.8Å; F437-W439 AromaticContact CG-CH2 3.59Å; F437-W439 HydrophobicContact CG-CH2 3.59Å; F437-W439 AromaticContact CG-CZ2 3.25Å; F437-W439 HydrophobicContact CG-CZ2 3.25Å; F437-W439 HydrophobicContact CG-CZ3 4.38Å; F437-W439 HydrophobicContact CZ-CH2 4.44Å; F437-W439 PolarHBondContact O-N 3.03Å; W439-A442 PolarHBondContact O-N 3.44Å; W439-V443 WeakPolarHBondContact O-CG2 3.38Å; W439-V443 PolarHBondContact O-N 2.96Å; W439-I608 HydrophobicContact CH2-CD1 4.49Å; W439-I608 HydrophobicContact CH2-CG2 4.44Å; W439-I608 HydrophobicContact CZ2-CD1 4.4Å
440S87.3Confident84.2Confident42 Ų4247.2 Ų47.229%0.29427%0.27SS..Hα-helixtrans-64.9-41.5179.2-61.60000111.4A389 N438 A442 V443 T444A389-S440 PolarHBondContact N-OG 3.24Å; A389-S440 VanDerWaalsContact N-OG 3.12Å; N438-S440 VanDerWaalsContact C-N 3.28Å; N438-S440 PolarHBondContact O-N 2.78Å; S440-A442 VanDerWaalsContact C-N 3.34Å; S440-V443 PolarHBondContact O-N 2.83Å; S440-T444 WeakPolarHBondContact O-CB 3.04Å; S440-T444 PolarHBondContact O-N 3.07Å; S440-T444 PolarHBondContact O-OG1 2.99Å
441A85.9Confident84.4Confident32 Ų3245.1 Ų45.126%0.26426%0.257SS..Hα-helixtrans-63-40.917300000111.5N438 T444 Q445N438-A441 HydrophobicContact CB-CB 4.09Å; N438-A441 WeakPolarHBondContact ND2-CB 3.35Å; N438-A441 PolarHBondContact O-N 3.24Å; N438-A441 WeakPolarHBondContact OD1-CB 3.4Å; N438-A441 PolarHBondContact OD1-N 3.37Å; N438-A441 VanDerWaalsContact OD1-N 3.14Å; A441-T444 PolarHBondContact O-N 3.24Å; A441-Q445 WeakPolarHBondContact O-CB 3.48Å; A441-Q445 PolarHBondContact O-N 3.42Å
442A89.2Confident85Confident1 Ų144.7 Ų44.71%0.00825%0.253CS..Hα-helixtrans-67-41.3177.900000113.7L394 Y423 A427 N438 W439 S440 T444 Q445 L446L394-A442 HydrophobicContact CD2-CB 4.5Å; Y423-A442 WeakPolarHBondContact CD1-O 3.24Å; Y423-A442 VanDerWaalsContact O-CB 3.27Å; Y423-A442 WeakPolarHBondContact O-CB 3.41Å; A427-A442 HydrophobicContact CB-CB 3.58Å; N438-A442 PolarHBondContact O-N 2.81Å; N438-A442 VanDerWaalsContact O-N 3.1Å; W439-A442 PolarHBondContact O-N 3.44Å; S440-A442 VanDerWaalsContact C-N 3.34Å; A442-T444 VanDerWaalsContact C-N 3.31Å; A442-Q445 PolarHBondContact O-N 2.89Å; A442-L446 WeakPolarHBondContact O-CB 3.33Å; A442-L446 PolarHBondContact O-N 3.16Å
443V88Confident85.7Confident20 Ų2039.1 Ų39.112%0.12121%0.214CC..Hα-helixtrans-63.7-40.5173.5171.40000110.7A389 T393 L394 W439 S440 L446 R447A389-V443 HydrophobicContact CB-CG2 3.97Å; T393-V443 HydrophobicContact CG2-CG2 4.37Å; L394-V443 HydrophobicContact CB-CG2 4.07Å; L394-V443 HydrophobicContact CD1-CG2 4.01Å; W439-V443 WeakPolarHBondContact O-CG2 3.38Å; W439-V443 PolarHBondContact O-N 2.96Å; S440-V443 PolarHBondContact O-N 2.83Å; V443-L446 PolarHBondContact O-N 3.34Å; V443-R447 VanDerWaalsContact O-CG 3.3Å; V443-R447 WeakPolarHBondContact O-CG 3.22Å; V443-R447 PolarHBondContact O-N 2.91Å
444T87.4Confident86.4Confident27 Ų2737.3 Ų37.317%0.16620%0.201CC..Hα-helixtrans-63.7-45.3175.5-58.40000111.1S440 A441 A442 L446 R447 N448S440-T444 WeakPolarHBondContact O-CB 3.04Å; S440-T444 PolarHBondContact O-N 3.07Å; S440-T444 PolarHBondContact O-OG1 2.99Å; A441-T444 PolarHBondContact O-N 3.24Å; A442-T444 VanDerWaalsContact C-N 3.31Å; T444-L446 PolarHBondContact O-N 3.35Å; T444-R447 WeakPolarHBondContact O-CB 3.37Å; T444-R447 PolarHBondContact O-N 2.99Å; T444-N448 PolarHBondContact O-N 2.82Å
445Q89Confident87.4Confident61 Ų6132.9 Ų32.929%0.28517%0.172SC..Hα-helixtrans-62.7-41.9176.4-169.265.326.800111.4Y423 K426 A441 A442 R447 N448 D449Y423-Q445 HydrophobicContact CD1-CB 4.41Å; Y423-Q445 HydrophobicContact CE1-CB 4.21Å; Y423-Q445 HydrophobicContact CE1-CG 4.08Å; K426-Q445 HydrophobicContact CD-CG 4.25Å; A441-Q445 WeakPolarHBondContact O-CB 3.48Å; A441-Q445 PolarHBondContact O-N 3.42Å; A442-Q445 PolarHBondContact O-N 2.89Å; Q445-R447 VanDerWaalsContact C-N 3.27Å; Q445-R447 PolarHBondContact O-N 2.81Å; Q445-N448 PolarHBondContact O-N 3.03Å; Q445-D449 PolarHBondContact NE2-OD1 3.33Å; Q445-D449 VanDerWaalsContact O-CB 3.24Å; Q445-D449 WeakPolarHBondContact O-CB 2.99Å; Q445-D449 VanDerWaalsContact O-CG 3.26Å; Q445-D449 PolarHBondContact O-N 3.34Å
446L89.2Confident88.4Confident0 Ų027 Ų270%014%0.141CC..Hα-helixtrans-58.3-41.6175.1170.660.5000111.5L394 A397 V401 Y423 A442 V443 T444 N450 W568L394-L446 HydrophobicContact CD1-CD2 3.89Å; A397-L446 HydrophobicContact CB-CD2 3.61Å; V401-L446 HydrophobicContact CG2-CD1 4.34Å; V401-L446 HydrophobicContact CG2-CG 4.46Å; Y423-L446 HydrophobicContact CD1-CB 3.71Å; Y423-L446 HydrophobicContact CD2-CB 4.39Å; Y423-L446 HydrophobicContact CD2-CD1 4Å; Y423-L446 HydrophobicContact CE1-CB 3.63Å; Y423-L446 HydrophobicContact CE1-CD1 4.31Å; Y423-L446 VanDerWaalsContact CE1-N 3.27Å; Y423-L446 HydrophobicContact CE2-CB 4.33Å; Y423-L446 HydrophobicContact CE2-CD1 3.55Å; Y423-L446 HydrophobicContact CE2-CG 4.49Å; Y423-L446 HydrophobicContact CG-CB 4.11Å; A442-L446 WeakPolarHBondContact O-CB 3.33Å; A442-L446 PolarHBondContact O-N 3.16Å; V443-L446 PolarHBondContact O-N 3.34Å; T444-L446 PolarHBondContact O-N 3.35Å; L446-N450 VanDerWaalsContact O-CB 3.26Å; L446-N450 WeakPolarHBondContact O-CB 3.26Å; L446-N450 PolarHBondContact O-N 3.36Å; L446-W568 HydrophobicContact CD1-CH2 3.68Å; L446-W568 HydrophobicContact CD1-CZ2 3.59Å
447R87.7Confident88.9Confident102 Ų10222.1 Ų22.139%0.38512%0.116SC..Hα-helixtrans-68.3-43176.6-70.6172.763.3-166.5-3.9112.1F374 V443 T444 Q445 G451F374-R447 HydrophobicContact CB-CB 4.18Å; F374-R447 VanDerWaalsContact CD2-C 3.49Å; F374-R447 HydrophobicContact CD2-CB 3.98Å; F374-R447 VanDerWaalsContact CD2-O 3.31Å; F374-R447 WeakPolarHBondContact CD2-O 3.46Å; F374-R447 WeakPolarHBondContact CE2-O 3.23Å; F374-R447 HydrophobicContact CG-CB 4.18Å; V443-R447 VanDerWaalsContact O-CG 3.3Å; V443-R447 WeakPolarHBondContact O-CG 3.22Å; V443-R447 PolarHBondContact O-N 2.91Å; T444-R447 WeakPolarHBondContact O-CB 3.37Å; T444-R447 PolarHBondContact O-N 2.99Å; Q445-R447 VanDerWaalsContact C-N 3.27Å; Q445-R447 PolarHBondContact O-N 2.81Å; R447-G451 WeakPolarHBondContact O-CA 3.45Å; R447-G451 PolarHBondContact O-N 3.05Å
448N90.3Very high89.2Confident6 Ų620.2 Ų20.23%0.03211%0.108CC..Hα-helixtrans-62.2-53.2175.7-70.6-21000111.2F374 T444 Q445 I452 F453F374-N448 WeakPolarHBondContact CB-OD1 3.23Å; F374-N448 WeakPolarHBondContact CD2-OD1 3.41Å; F374-N448 PolarHBondContact N-OD1 2.77Å; T444-N448 PolarHBondContact O-N 2.82Å; Q445-N448 PolarHBondContact O-N 3.03Å; N448-I452 PolarHBondContact O-N 3.02Å; N448-F453 HydrophobicContact CB-CD2 3.89Å; N448-F453 HydrophobicContact CB-CE1 4.46Å; N448-F453 HydrophobicContact CB-CE2 3.5Å; N448-F453 HydrophobicContact CB-CZ 3.82Å; N448-F453 PolarHBondContact O-N 3.11Å
449D90.7Very high89.4Confident0 Ų017.2 Ų17.20%09%0.092CC..Iπ-helixtrans-58.4-55.5-177.8-74.8-3.3000110Y423 K426 Q445 F453 W454 G564Y423-D449 WeakPolarHBondContact OH-CB 3.4Å; Y423-D449 PolarHBondContact OH-OD2 3.05Å; K426-D449 IonicContact NZ-OD2 2.9Å; K426-D449 PolarHBondContact NZ-OD2 2.79Å; Q445-D449 PolarHBondContact NE2-OD1 3.33Å; Q445-D449 VanDerWaalsContact O-CB 3.24Å; Q445-D449 WeakPolarHBondContact O-CB 2.99Å; Q445-D449 VanDerWaalsContact O-CG 3.26Å; Q445-D449 PolarHBondContact O-N 3.34Å; D449-F453 WeakPolarHBondContact OD1-CD2 3.09Å; D449-W454 WeakPolarHBondContact O-CB 3.35Å; D449-W454 PolarHBondContact O-N 3.14Å; D449-G564 WeakPolarHBondContact OD2-CA 3.29Å
450N85.9Confident89.7Confident5 Ų515.6 Ų15.63%0.0279%0.086CC..Iπ-helixtrans-75.6-36.3-177.4-174.4-106.8000114.1P247 V401 W405 L446 P455 W568P247-N450 WeakPolarHBondContact CD-O 3.47Å; P247-N450 WeakPolarHBondContact CG-O 3.39Å; P247-N450 WeakPolarHBondContact CG-OD1 3.16Å; V401-N450 HydrophobicContact CG1-CB 3.94Å; V401-N450 WeakPolarHBondContact CG1-ND2 3.49Å; V401-N450 VanDerWaalsContact CG1-OD1 3.26Å; V401-N450 WeakPolarHBondContact CG1-OD1 3.39Å; V401-N450 HydrophobicContact CG2-CB 4.22Å; W405-N450 PolarHBondContact NE1-ND2 2.93Å; W405-N450 PolarHBondContact NE1-OD1 2.84Å; L446-N450 VanDerWaalsContact O-CB 3.26Å; L446-N450 WeakPolarHBondContact O-CB 3.26Å; L446-N450 PolarHBondContact O-N 3.36Å; N450-P455 WeakPolarHBondContact O-CD 3.39Å; N450-P455 VanDerWaalsContact O-CG 3.32Å; N450-P455 WeakPolarHBondContact O-CG 3.45Å; N450-W568 HydrophobicContact CB-CH2 3.98Å; N450-W568 HydrophobicContact CB-CZ2 3.69Å
451G85.8Confident89.8Confident12 Ų1213.6 Ų13.612%0.1247%0.072CC..Iπ-helixtrans-76.5-35.8-171.100000113P247 R447P247-G451 WeakPolarHBondContact CD-O 3.36Å; R447-G451 WeakPolarHBondContact O-CA 3.45Å; R447-G451 PolarHBondContact O-N 3.05Å
452I91.8Very high90Very high15 Ų1512.6 Ų12.68%0.0776%0.062CC..Iπ-helixtrans-140.6-51.3-172.5-66-65.4000112.8T369 E373 F374 N448 W454 P455 V456T369-I452 HydrophobicContact CG2-CG2 3.43Å; T369-I452 VanDerWaalsContact CG2-CG2 3.43Å; E373-I452 HydrophobicContact CB-CB 4.3Å; E373-I452 HydrophobicContact CB-CG1 4.24Å; E373-I452 HydrophobicContact CG-CB 3.87Å; E373-I452 HydrophobicContact CG-CG1 4.18Å; E373-I452 HydrophobicContact CG-CG2 3.68Å; F374-I452 HydrophobicContact CE2-CB 4.5Å; F374-I452 HydrophobicContact CE2-CG1 3.81Å; F374-I452 HydrophobicContact CZ-CG1 3.96Å; N448-I452 PolarHBondContact O-N 3.02Å; I452-W454 PolarHBondContact O-N 3.28Å; I452-P455 WeakPolarHBondContact O-CD 3.44Å; I452-V456 HydrophobicContact CG2-CG2 4.01Å; I452-V456 WeakPolarHBondContact O-CB 3.31Å; I452-V456 VanDerWaalsContact O-CG2 3.25Å; I452-V456 WeakPolarHBondContact O-CG2 3.49Å; I452-V456 PolarHBondContact O-N 3.48Å
453F93Very high90.3Very high1 Ų112.5 Ų12.50%0.0046%0.062CC..Iπ-helixtrans-62.5-48.7-170.2-59.4-19.8000112.4T369 T370 E373 N448 D449 V456 Y457 H561 M565T369-F453 HydrophobicContact CG2-CD1 4.01Å; T369-F453 HydrophobicContact CG2-CE1 4.45Å; T369-F453 WeakPolarHBondContact OG1-CE1 3.24Å; T370-F453 VanDerWaalsContact O-CE1 3.28Å; T370-F453 WeakPolarHBondContact O-CE1 3.31Å; E373-F453 HydrophobicContact CB-CE1 4.43Å; E373-F453 HydrophobicContact CG-CD1 4.15Å; E373-F453 HydrophobicContact CG-CE1 3.51Å; E373-F453 HydrophobicContact CG-CZ 4.3Å; N448-F453 HydrophobicContact CB-CD2 3.89Å; N448-F453 HydrophobicContact CB-CE1 4.46Å; N448-F453 HydrophobicContact CB-CE2 3.5Å; N448-F453 HydrophobicContact CB-CZ 3.82Å; N448-F453 PolarHBondContact O-N 3.11Å; D449-F453 WeakPolarHBondContact OD1-CD2 3.09Å; F453-V456 PolarHBondContact O-N 2.94Å; F453-Y457 VanDerWaalsContact O-CB 3.29Å; F453-Y457 WeakPolarHBondContact O-CB 3.3Å; F453-Y457 PolarHBondContact O-N 3.14Å; F453-H561 HydrophobicContact CB-CB 4.46Å; F453-H561 AromaticContact CD1-CD2 3.8Å; F453-H561 AromaticContact CD1-NE2 3.6Å; F453-H561 HydrophobicContact CD2-CB 4.02Å; F453-H561 AromaticContact CD2-CD2 3.56Å; F453-H561 AromaticContact CD2-CE1 3.84Å; F453-H561 AromaticContact CD2-CG 3.48Å; F453-H561 VanDerWaalsContact CD2-CG 3.48Å; F453-H561 AromaticContact CD2-ND1 3.68Å; F453-H561 AromaticContact CD2-NE2 3.78Å; F453-H561 AromaticContact CE1-CE1 3.91Å; F453-H561 AromaticContact CE1-NE2 3.61Å; F453-H561 AromaticContact CE2-CE1 3.47Å; F453-H561 VanDerWaalsContact CE2-CE1 3.47Å; F453-H561 WeakPolarHBondContact CE2-CE1 3.28Å; F453-H561 AromaticContact CE2-CG 3.84Å; F453-H561 AromaticContact CE2-ND1 3.51Å; F453-H561 AromaticContact CE2-NE2 3.78Å; F453-H561 HydrophobicContact CG-CB 4.49Å; F453-H561 AromaticContact CG-CD2 3.44Å; F453-H561 VanDerWaalsContact CG-CD2 3.44Å; F453-H561 WeakPolarHBondContact CG-CD2 3.11Å; F453-H561 AromaticContact CG-CG 3.86Å; F453-H561 AromaticContact CG-NE2 3.7Å; F453-H561 AromaticContact CZ-CE1 3.52Å; F453-H561 AromaticContact CZ-NE2 3.71Å; F453-M565 HydrophobicContact CB-CE 3.54Å; F453-M565 HydrophobicContact CB-SD 4.49Å
454W89.2Confident90.5Very high3 Ų313 Ų131%0.0116%0.061CC..Hα-helixtrans-63.9-51.8177.3165.8-111.5000112.2D449 I452 V456 Y457 A458 M565 W568 P569 F572 A574 F578D449-W454 WeakPolarHBondContact O-CB 3.35Å; D449-W454 PolarHBondContact O-N 3.14Å; I452-W454 PolarHBondContact O-N 3.28Å; W454-V456 VanDerWaalsContact C-N 3.31Å; W454-V456 PolarHBondContact O-N 2.89Å; W454-Y457 HydrophobicContact CE3-CD1 4.21Å; W454-Y457 HydrophobicContact CZ3-CD1 4.01Å; W454-Y457 PolarHBondContact O-N 2.89Å; W454-A458 HydrophobicContact CD2-CB 4.47Å; W454-A458 HydrophobicContact CH2-CB 4.43Å; W454-A458 HydrophobicContact CZ2-CB 4.25Å; W454-A458 WeakPolarHBondContact O-CB 3.31Å; W454-A458 PolarHBondContact O-N 2.97Å; W454-M565 VanDerWaalsContact CA-SD 3.5Å; W454-M565 HydrophobicContact CB-CE 4.01Å; W454-M565 HydrophobicContact CB-SD 4.11Å; W454-M565 HydrophobicContact CE3-SD 3.92Å; W454-W568 HydrophobicContact CB-CB 4.38Å; W454-W568 HydrophobicContact CB-CG 4.17Å; W454-W568 HydrophobicContact CD2-CB 3.54Å; W454-W568 HydrophobicContact CD2-CG 4.25Å; W454-W568 HydrophobicContact CE3-CB 4.01Å; W454-W568 HydrophobicContact CG-CB 3.69Å; W454-W568 AromaticContact CG-CD1 3.98Å; W454-W568 AromaticContact CG-CG 3.92Å; W454-W568 HydrophobicContact CG-CG 3.92Å; W454-W568 HydrophobicContact CH2-CB 4.49Å; W454-W568 HydrophobicContact CZ2-CB 4.17Å; W454-W568 HydrophobicContact CZ3-CB 4.47Å; W454-P569 HydrophobicContact CH2-CB 3.53Å; W454-P569 HydrophobicContact CH2-CG 3.29Å; W454-P569 HydrophobicContact CZ2-CB 4.22Å; W454-P569 HydrophobicContact CZ2-CG 4.27Å; W454-P569 HydrophobicContact CZ3-CB 4.31Å; W454-P569 VanDerWaalsContact CZ3-CD 3.43Å; W454-P569 HydrophobicContact CZ3-CG 3.56Å; W454-F572 AromaticContact CD1-CE2 3.81Å; W454-F572 HydrophobicContact CZ2-CD2 4.38Å; W454-F572 AromaticContact NE1-CD2 3.6Å; W454-F572 AromaticContact NE1-CE2 3.49Å; W454-A574 HydrophobicContact CZ2-CB 4.42Å; W454-F578 HydrophobicContact CH2-CD2 4.08Å; W454-F578 HydrophobicContact CH2-CE1 4.38Å; W454-F578 AromaticContact CH2-CE2 3.07Å; W454-F578 HydrophobicContact CH2-CE2 3.07Å; W454-F578 AromaticContact CH2-CZ 3.24Å; W454-F578 HydrophobicContact CH2-CZ 3.24Å; W454-F578 AromaticContact CZ2-CE2 3.77Å; W454-F578 HydrophobicContact CZ2-CE2 3.77Å; W454-F578 HydrophobicContact CZ2-CZ 4.23Å; W454-F578 HydrophobicContact CZ3-CE1 4.49Å; W454-F578 AromaticContact CZ3-CE2 3.9Å; W454-F578 HydrophobicContact CZ3-CE2 3.9Å; W454-F578 AromaticContact CZ3-CZ 3.55Å; W454-F578 HydrophobicContact CZ3-CZ 3.55Å
455P90.5Very high90.6Very high0 Ų015.2 Ų15.20%07%0.072CC..Hα-helixtrans-52.4-42.3173.7-32.737000115.5S243 L245 W405 N450 I452 D459S243-P455 PolarHBondContact OG-O 2.93Å; L245-P455 HydrophobicContact CB-CB 4.03Å; W405-P455 HydrophobicContact CZ2-CG 4.49Å; N450-P455 WeakPolarHBondContact O-CD 3.39Å; N450-P455 VanDerWaalsContact O-CG 3.32Å; N450-P455 WeakPolarHBondContact O-CG 3.45Å; I452-P455 WeakPolarHBondContact O-CD 3.44Å; P455-D459 VanDerWaalsContact O-CB 3.31Å; P455-D459 WeakPolarHBondContact O-CB 3.26Å; P455-D459 PolarHBondContact O-N 2.59Å
456V93.7Very high90.7Very high0 Ų014 Ų140%07%0.073CC..Hα-helixtrans-69.5-44.3178.9168.30000110.4G242 L367 T369 I452 F453 W454 D459 A460 L472G242-V456 WeakPolarHBondContact O-CG2 3.38Å; L367-V456 HydrophobicContact CD1-CG1 3.83Å; L367-V456 WeakPolarHBondContact CD1-O 3.5Å; L367-V456 HydrophobicContact CG-CG1 3.98Å; T369-V456 HydrophobicContact CG2-CB 4Å; T369-V456 HydrophobicContact CG2-CG1 3.96Å; T369-V456 HydrophobicContact CG2-CG2 3.82Å; I452-V456 HydrophobicContact CG2-CG2 4.01Å; I452-V456 WeakPolarHBondContact O-CB 3.31Å; I452-V456 VanDerWaalsContact O-CG2 3.25Å; I452-V456 WeakPolarHBondContact O-CG2 3.49Å; I452-V456 PolarHBondContact O-N 3.48Å; F453-V456 PolarHBondContact O-N 2.94Å; W454-V456 VanDerWaalsContact C-N 3.31Å; W454-V456 PolarHBondContact O-N 2.89Å; V456-D459 PolarHBondContact O-N 3.23Å; V456-A460 WeakPolarHBondContact O-CB 3.39Å; V456-A460 PolarHBondContact O-N 3.34Å; V456-L472 HydrophobicContact CG1-CD1 4.06Å
457Y92Very high90.9Very high1 Ų116.9 Ų16.90%0.00410%0.102CC..Hα-helixtrans-62.9-44.7177.2-176.7-110.3000112.3F453 W454 D459 A460 V461 L472 G544 Y560 M565 F578 F584F453-Y457 VanDerWaalsContact O-CB 3.29Å; F453-Y457 WeakPolarHBondContact O-CB 3.3Å; F453-Y457 PolarHBondContact O-N 3.14Å; W454-Y457 HydrophobicContact CE3-CD1 4.21Å; W454-Y457 HydrophobicContact CZ3-CD1 4.01Å; W454-Y457 PolarHBondContact O-N 2.89Å; Y457-D459 PolarHBondContact O-N 3.3Å; Y457-A460 VanDerWaalsContact O-CB 3.31Å; Y457-A460 WeakPolarHBondContact O-CB 3.35Å; Y457-A460 PolarHBondContact O-N 2.94Å; Y457-V461 HydrophobicContact CD1-CG2 4.42Å; Y457-V461 HydrophobicContact CE1-CG2 4.03Å; Y457-V461 HydrophobicContact CE2-CG2 4.19Å; Y457-V461 WeakPolarHBondContact O-CG2 3.48Å; Y457-V461 PolarHBondContact O-N 3.35Å; Y457-L472 HydrophobicContact CD2-CD2 3.89Å; Y457-L472 HydrophobicContact CE2-CD2 4.37Å; Y457-G544 VanDerWaalsContact CE2-O 3.23Å; Y457-G544 WeakPolarHBondContact CE2-O 3.44Å; Y457-G544 VanDerWaalsContact OH-C 3.28Å; Y457-G544 PolarHBondContact OH-O 2.9Å; Y457-Y560 AromaticContact CD2-CD1 3.78Å; Y457-Y560 HydrophobicContact CD2-CD1 3.78Å; Y457-Y560 HydrophobicContact CD2-CG 4.44Å; Y457-Y560 HydrophobicContact CG-CD1 4.16Å; Y457-M565 VanDerWaalsContact CB-SD 3.58Å; Y457-M565 HydrophobicContact CD1-CB 3.89Å; Y457-M565 HydrophobicContact CD1-CG 3.97Å; Y457-M565 HydrophobicContact CD1-SD 3.97Å; Y457-M565 HydrophobicContact CE1-CB 4.01Å; Y457-M565 HydrophobicContact CE1-CG 4.46Å; Y457-M565 HydrophobicContact CG-CB 4.45Å; Y457-M565 HydrophobicContact CG-CG 4.04Å; Y457-M565 HydrophobicContact CG-SD 3.91Å; Y457-F578 HydrophobicContact CE1-CE1 4.13Å; Y457-F578 HydrophobicContact CE1-CZ 4.47Å; Y457-F584 HydrophobicContact CE1-CE2 4.13Å
458A89.3Confident91.3Very high0 Ų012.5 Ų12.50%09%0.089CC..Hα-helixtrans-63.8-39.6176.200000112L245 W454 A460 V461 T462 F578L245-A458 HydrophobicContact CD1-CB 3.51Å; W454-A458 HydrophobicContact CD2-CB 4.47Å; W454-A458 HydrophobicContact CH2-CB 4.43Å; W454-A458 HydrophobicContact CZ2-CB 4.25Å; W454-A458 WeakPolarHBondContact O-CB 3.31Å; W454-A458 PolarHBondContact O-N 2.97Å; A458-A460 VanDerWaalsContact C-N 3.34Å; A458-A460 PolarHBondContact O-N 2.91Å; A458-V461 PolarHBondContact O-N 2.94Å; A458-T462 VanDerWaalsContact O-CG2 3.31Å; A458-T462 WeakPolarHBondContact O-CG2 3.2Å; A458-T462 PolarHBondContact O-N 3.41Å; A458-T462 PolarHBondContact O-OG1 2.83Å; A458-F578 HydrophobicContact CB-CZ 4.37Å
459D93.2Very high91.6Very high0 Ų015.2 Ų15.20%011%0.106CC..Hα-helixtrans-60.7-43.9172.3-172.77.1000111.1S222 M357 R360 Y365 L367 P455 V456 Y457 V461 T462 M463S222-D459 WeakPolarHBondContact CB-OD2 3.47Å; S222-D459 PolarHBondContact OG-OD2 2.86Å; M357-D459 HydrophobicContact CE-CB 4.36Å; R360-D459 IonicContact CZ-OD1 2.69Å; R360-D459 PolarHBondContact NH1-O 3.2Å; R360-D459 IonicContact NH1-OD1 3.52Å; R360-D459 PolarHBondContact NH1-OD1 3.12Å; R360-D459 IonicContact NH2-OD1 3.6Å; R360-D459 PolarHBondContact NH2-OD1 2.88Å; Y365-D459 WeakPolarHBondContact CE1-OD1 3.39Å; Y365-D459 PolarHBondContact OH-OD1 2.97Å; Y365-D459 PolarHBondContact OH-OD2 3.36Å; L367-D459 HydrophobicContact CD1-CB 4.18Å; P455-D459 VanDerWaalsContact O-CB 3.31Å; P455-D459 WeakPolarHBondContact O-CB 3.26Å; P455-D459 PolarHBondContact O-N 2.59Å; V456-D459 PolarHBondContact O-N 3.23Å; Y457-D459 PolarHBondContact O-N 3.3Å; D459-V461 PolarHBondContact O-N 3.44Å; D459-T462 PolarHBondContact O-N 3.28Å; D459-T462 PolarHBondContact O-OG1 3.33Å; D459-M463 PolarHBondContact O-N 2.84Å
460A93.5Very high91.9Very high0 Ų015.3 Ų15.30%011%0.106CC..Hα-helixtrans-58-47.6176.200000112L367 V456 Y457 A458 M463 R464 V470 L539L367-A460 HydrophobicContact CD1-CB 3.9Å; L367-A460 HydrophobicContact CD2-CB 3.77Å; L367-A460 HydrophobicContact CG-CB 4.22Å; V456-A460 WeakPolarHBondContact O-CB 3.39Å; V456-A460 PolarHBondContact O-N 3.34Å; Y457-A460 VanDerWaalsContact O-CB 3.31Å; Y457-A460 WeakPolarHBondContact O-CB 3.35Å; Y457-A460 PolarHBondContact O-N 2.94Å; A458-A460 VanDerWaalsContact C-N 3.34Å; A458-A460 PolarHBondContact O-N 2.91Å; A460-M463 PolarHBondContact O-N 3.46Å; A460-R464 WeakPolarHBondContact O-CB 3.3Å; A460-R464 PolarHBondContact O-N 3.03Å; A460-V470 HydrophobicContact CB-CG1 3.92Å; A460-L539 HydrophobicContact CB-CD2 3.71Å
461V90.4Very high92.5Very high0 Ų015.7 Ų15.70%011%0.107CC..Hα-helixtrans-66.6-42.5-178.5170.70000111.4Y457 A458 D459 M463 R464 N465 L539 F578Y457-V461 HydrophobicContact CD1-CG2 4.42Å; Y457-V461 HydrophobicContact CE1-CG2 4.03Å; Y457-V461 HydrophobicContact CE2-CG2 4.19Å; Y457-V461 WeakPolarHBondContact O-CG2 3.48Å; Y457-V461 PolarHBondContact O-N 3.35Å; A458-V461 PolarHBondContact O-N 2.94Å; D459-V461 PolarHBondContact O-N 3.44Å; V461-M463 PolarHBondContact O-N 3.29Å; V461-R464 WeakPolarHBondContact O-CB 3.27Å; V461-R464 PolarHBondContact O-N 2.86Å; V461-N465 WeakPolarHBondContact O-CB 3.32Å; V461-N465 PolarHBondContact O-N 2.92Å; V461-N465 PolarHBondContact O-OD1 2.85Å; V461-L539 HydrophobicContact CG2-CD2 4.22Å; V461-F578 HydrophobicContact CB-CE1 4.1Å; V461-F578 HydrophobicContact CG1-CD1 4.03Å; V461-F578 HydrophobicContact CG1-CE1 3.78Å; V461-F578 HydrophobicContact CG1-CZ 4.46Å; V461-F578 HydrophobicContact CG2-CE1 4.01Å
462T90.6Very high93Very high10 Ų1015.1 Ų15.16%0.06110%0.102CC..Hα-helixtrans-64.5-40.8177.558.90000112.2M357 R360 A458 D459 N465 A466 I577M357-T462 HydrophobicContact CB-CG2 4.04Å; M357-T462 HydrophobicContact SD-CG2 4.02Å; M357-T462 PolarHBondContact SD-OG1 3.13Å; R360-T462 PolarHBondContact NH1-OG1 3.46Å; A458-T462 VanDerWaalsContact O-CG2 3.31Å; A458-T462 WeakPolarHBondContact O-CG2 3.2Å; A458-T462 PolarHBondContact O-N 3.41Å; A458-T462 PolarHBondContact O-OG1 2.83Å; D459-T462 PolarHBondContact O-N 3.28Å; D459-T462 PolarHBondContact O-OG1 3.33Å; T462-N465 PolarHBondContact O-N 3.45Å; T462-A466 PolarHBondContact O-N 3.42Å; T462-I577 HydrophobicContact CG2-CG2 3.61Å
463M94.1Very high93.3Very high0 Ų014.7 Ų14.70%010%0.099CC..Hα-helixtrans-64.2-41.4175.1-178.163.483.100111.8R360 M363 Y365 D459 A460 V461 A466 G467 G468 V470R360-M463 VanDerWaalsContact NH2-CE 3.29Å; M363-M463 HydrophobicContact CG-CE 3.6Å; M363-M463 HydrophobicContact CG-SD 4.13Å; M363-M463 HydrophobicContact SD-CE 4.25Å; Y365-M463 HydrophobicContact CD1-CB 3.84Å; Y365-M463 HydrophobicContact CD1-CE 4.13Å; Y365-M463 HydrophobicContact CD1-CG 3.76Å; Y365-M463 HydrophobicContact CD2-CE 3.68Å; Y365-M463 HydrophobicContact CE1-CB 4.3Å; Y365-M463 HydrophobicContact CE1-CE 4.37Å; Y365-M463 HydrophobicContact CE2-CE 3.99Å; Y365-M463 HydrophobicContact CG-CB 4.4Å; Y365-M463 HydrophobicContact CG-CE 3.77Å; Y365-M463 HydrophobicContact CG-CG 3.81Å; D459-M463 PolarHBondContact O-N 2.84Å; A460-M463 PolarHBondContact O-N 3.46Å; V461-M463 PolarHBondContact O-N 3.29Å; M463-A466 PolarHBondContact O-N 3.05Å; M463-G467 PolarHBondContact O-N 3.13Å; M463-G468 WeakPolarHBondContact O-CA 3.38Å; M463-G468 PolarHBondContact O-N 3.21Å; M463-V470 HydrophobicContact CB-CG2 3.81Å; M463-V470 HydrophobicContact CG-CG2 3.63Å
464R92.4Very high93.4Very high29 Ų2914.6 Ų14.611%0.10910%0.099CC..Hα-helixtrans-59.4-47.3173.9-179.3-157.970.6172.9-1.8110.7A460 V461 A466 G467 V470 L539 D583A460-R464 WeakPolarHBondContact O-CB 3.3Å; A460-R464 PolarHBondContact O-N 3.03Å; V461-R464 WeakPolarHBondContact O-CB 3.27Å; V461-R464 PolarHBondContact O-N 2.86Å; R464-A466 VanDerWaalsContact C-N 3.27Å; R464-A466 PolarHBondContact O-N 3.16Å; R464-G467 WeakPolarHBondContact O-CA 3.45Å; R464-G467 PolarHBondContact O-N 2.86Å; R464-V470 HydrophobicContact CB-CG2 4.01Å; R464-L539 VanDerWaalsContact CD-O 3.27Å; R464-L539 WeakPolarHBondContact CD-O 3.14Å; R464-L539 WeakPolarHBondContact CG-O 3.48Å; R464-D583 IonicContact CZ-OD1 3.38Å; R464-D583 IonicContact CZ-OD2 3.9Å; R464-D583 IonicContact NH1-OD1 2.65Å; R464-D583 PolarHBondContact NH1-OD1 2.86Å; R464-D583 VanDerWaalsContact NH2-CG 3.3Å; R464-D583 IonicContact NH2-OD1 2.92Å; R464-D583 PolarHBondContact NH2-OD1 2.82Å; R464-D583 IonicContact NH2-OD2 2.86Å; R464-D583 PolarHBondContact NH2-OD2 2.99Å
465N90.1Very high93.8Very high74 Ų7414.5 Ų14.540%0.39610%0.098SC..Hα-helixtrans-65.6-30.5-178.3-68-4.9000112.3V461 T462 G467V461-N465 WeakPolarHBondContact O-CB 3.32Å; V461-N465 PolarHBondContact O-N 2.92Å; V461-N465 PolarHBondContact O-OD1 2.85Å; T462-N465 PolarHBondContact O-N 3.45Å; N465-G467 PolarHBondContact O-N 2.84Å
466A92.2Very high94Very high37 Ų3714.8 Ų14.831%0.30610%0.1SC..THydrogen-bonded Turntrans-70.2-7.7170.300000113.6R360 S362 T462 M463 R464R360-A466 HydrophobicContact CG-CB 3.68Å; S362-A466 VanDerWaalsContact CB-O 3.27Å; S362-A466 WeakPolarHBondContact CB-O 3.36Å; T462-A466 PolarHBondContact O-N 3.42Å; M463-A466 PolarHBondContact O-N 3.05Å; R464-A466 VanDerWaalsContact C-N 3.27Å; R464-A466 PolarHBondContact O-N 3.16Å
467G92.8Very high93.9Very high59 Ų5914.8 Ų14.861%0.60810%0.1SC*.THydrogen-bonded Turntrans97.79-178.200000114.6M463 R464 N465M463-G467 PolarHBondContact O-N 3.13Å; R464-G467 WeakPolarHBondContact O-CA 3.45Å; R464-G467 PolarHBondContact O-N 2.86Å; N465-G467 PolarHBondContact O-N 2.84Å
468G94.9Very high93.7Very high10 Ų1017.1 Ų17.110%0.10311%0.114CC..  trans-72.2147176.500000112.7M363 M463 V470M363-G468 WeakPolarHBondContact O-CA 3.48Å; M463-G468 WeakPolarHBondContact O-CA 3.38Å; M463-G468 PolarHBondContact O-N 3.21Å; G468-V470 PolarHBondContact O-N 3.05Å
469T96.3Very high93.4Very high64 Ų6418.3 Ų18.339%0.39312%0.119SC..  trans-84.1110.1169.4-58.80000108.7Y365 Y471 P538Y365-T469 PolarHBondContact N-O 3.31Å; T469-Y471 HydrophobicContact CG2-CE2 3.68Å; T469-P538 HydrophobicContact CG2-CB 4.05Å; T469-P538 HydrophobicContact CG2-CG 3.87Å
470V97.7Very high92.6Very high1 Ų120.4 Ų20.41%0.00613%0.134CC..EExtended strand (participates in β ladder)trans-109.6129.7-169.6-176.60000111.5Y365 L367 A460 M463 R464 G468 P538 L539Y365-V470 CarbonylContact O-C 3.13Å; Y365-V470 VanDerWaalsContact O-CA 3.26Å; Y365-V470 WeakPolarHBondContact O-CA 3.42Å; L367-V470 HydrophobicContact CD2-CG1 3.45Å; L367-V470 VanDerWaalsContact CD2-CG1 3.45Å; A460-V470 HydrophobicContact CB-CG1 3.92Å; M463-V470 HydrophobicContact CB-CG2 3.81Å; M463-V470 HydrophobicContact CG-CG2 3.63Å; R464-V470 HydrophobicContact CB-CG2 4.01Å; G468-V470 PolarHBondContact O-N 3.05Å; V470-P538 CarbonylContact O-C 3.51Å; V470-P538 WeakPolarHBondContact O-CA 3.24Å; V470-L539 HydrophobicContact CB-CB 4.09Å; V470-L539 HydrophobicContact CG1-CB 4.27Å; V470-L539 HydrophobicContact CG1-CD2 4.37Å; V470-L539 PolarHBondContact O-N 3.15Å
471Y98Very high91.6Very high13 Ų1328.3 Ų28.35%0.05118%0.176CC..EExtended strand (participates in β ladder)trans-115.2109.9175.1-64.3-81.5000110.1Y365 L366 L367 T469 F520 S524 P526 W536 P538Y365-Y471 PolarHBondContact O-N 3Å; L366-Y471 WeakPolarHBondContact CA-O 3.5Å; L367-Y471 PolarHBondContact N-O 3.45Å; L367-Y471 VanDerWaalsContact O-O 3.09Å; T469-Y471 HydrophobicContact CG2-CE2 3.68Å; Y471-F520 HydrophobicContact CD2-CD2 4.02Å; Y471-F520 AromaticContact CD2-CE2 3.84Å; Y471-F520 HydrophobicContact CD2-CE2 3.84Å; Y471-F520 HydrophobicContact CE2-CD2 4.24Å; Y471-F520 HydrophobicContact CE2-CE2 4.13Å; Y471-S524 WeakPolarHBondContact CE2-O 2.95Å; Y471-P526 HydrophobicContact CD1-CG 3.64Å; Y471-P526 HydrophobicContact CD2-CG 4.25Å; Y471-P526 VanDerWaalsContact CE1-CD 3.49Å; Y471-P526 HydrophobicContact CE1-CG 3.84Å; Y471-P526 HydrophobicContact CE2-CG 4.41Å; Y471-P526 HydrophobicContact CG-CG 3.85Å; Y471-W536 HydrophobicContact CD1-CB 4.42Å; Y471-W536 AromaticContact CD1-CD1 3.76Å; Y471-W536 HydrophobicContact CD1-CD2 4.17Å; Y471-W536 AromaticContact CD1-CG 3.86Å; Y471-W536 HydrophobicContact CD1-CG 3.86Å; Y471-W536 WeakPolarHBondContact CE1-O 3.49Å; Y471-P538 HydrophobicContact CD1-CG 4.45Å; Y471-P538 HydrophobicContact CE1-CB 4.31Å; Y471-P538 HydrophobicContact CE1-CG 3.68Å
472L97.2Very high90.8Very high1 Ų132.6 Ų32.61%0.00520%0.195CC..EExtended strand (participates in β ladder)trans-98.4131.8-179.7-176.460.8000111.1L367 V456 Y457 W536 L539 Y547 L548 Y560L367-L472 HydrophobicContact CD2-CD1 4.34Å; L367-L472 HydrophobicContact CG-CD1 4.12Å; L367-L472 CarbonylContact O-C 3.55Å; L367-L472 VanDerWaalsContact O-CA 3.26Å; L367-L472 WeakPolarHBondContact O-CA 3.39Å; V456-L472 HydrophobicContact CG1-CD1 4.06Å; Y457-L472 HydrophobicContact CD2-CD2 3.89Å; Y457-L472 HydrophobicContact CE2-CD2 4.37Å; L472-W536 WeakPolarHBondContact O-CZ2 3.41Å; L472-W536 PolarHBondContact O-NE1 3.42Å; L472-L539 HydrophobicContact CB-CD1 4.37Å; L472-L539 HydrophobicContact CD2-CD1 4.14Å; L472-Y547 CarbonylContact O-C 3.54Å; L472-Y547 VanDerWaalsContact O-CA 3.23Å; L472-Y547 WeakPolarHBondContact O-CA 3.34Å; L472-Y547 WeakPolarHBondContact O-CB 3.05Å; L472-L548 PolarHBondContact O-N 3.22Å; L472-Y560 HydrophobicContact CD1-CD2 4.46Å; L472-Y560 HydrophobicContact CD1-CE1 4.31Å; L472-Y560 HydrophobicContact CD1-CE2 4.13Å; L472-Y560 HydrophobicContact CD2-CD1 3.83Å; L472-Y560 HydrophobicContact CD2-CD2 3.87Å; L472-Y560 HydrophobicContact CD2-CE1 4.28Å; L472-Y560 HydrophobicContact CD2-CE2 4.34Å; L472-Y560 HydrophobicContact CD2-CG 3.59Å; L472-Y560 HydrophobicContact CG-CD2 4.04Å; L472-Y560 HydrophobicContact CG-CE2 4.16Å; L472-Y560 HydrophobicContact CG-CG 4.26Å
473Y97.3Very high89.9Confident5 Ų538.1 Ų38.12%0.0222%0.224CC..EExtended strand (participates in β ladder)trans-126.8160.1172.674-84.2000114L366 L367 G368 T369 F475 D490 W536 L548 I550L366-Y473 HydrophobicContact CD2-CD1 3.82Å; L366-Y473 HydrophobicContact CD2-CE1 3.72Å; L367-Y473 WeakPolarHBondContact O-CD1 3.17Å; L367-Y473 PolarHBondContact O-N 3.31Å; G368-Y473 VanDerWaalsContact CA-CE1 3.43Å; G368-Y473 WeakPolarHBondContact CA-O 3.38Å; T369-Y473 PolarHBondContact N-O 3.32Å; Y473-F475 HydrophobicContact CD2-CB 4.27Å; Y473-F475 HydrophobicContact CE2-CB 4.02Å; Y473-D490 PolarHBondContact OH-OD2 2.86Å; Y473-W536 AromaticContact CD1-CH2 3.89Å; Y473-W536 HydrophobicContact CD1-CH2 3.89Å; Y473-W536 HydrophobicContact CD1-CZ2 4.2Å; Y473-W536 HydrophobicContact CG-CH2 4.08Å; Y473-W536 HydrophobicContact CG-CZ2 4.31Å; Y473-L548 CarbonylContact C-O 3.18Å; Y473-L548 WeakPolarHBondContact CA-O 3.33Å; Y473-L548 WeakPolarHBondContact CB-O 3.03Å; Y473-I550 HydrophobicContact CD2-CD1 3.83Å; Y473-I550 HydrophobicContact CG-CD1 4.12Å
474S96.2Very high89.2Confident0 Ų039.8 Ų39.80%024%0.236CC..EExtended strand (participates in β ladder)trans-123.2125.5157.6-157.60000109.7T369 D476 L548 I550T369-S474 CarbonylContact O-C 3.51Å; T369-S474 VanDerWaalsContact O-CA 3.28Å; T369-S474 WeakPolarHBondContact O-CA 3.35Å; S474-D476 PolarHBondContact O-N 3.13Å; S474-D476 PolarHBondContact OG-OD1 3.25Å; S474-L548 PolarHBondContact N-O 2.88Å; S474-I550 PolarHBondContact O-N 3.43Å
475F96.5Very high88.8Confident0 Ų038.6 Ų38.60%023%0.232CC..EExtended strand (participates in β ladder)trans-81.7101.3172.1-164.5-86000108.1T369 K371 Y473 Y477 T485 V489 D490 Y493 I509 I513 I550T369-F475 PolarHBondContact O-N 3.35Å; K371-F475 PolarHBondContact N-O 2.85Å; Y473-F475 HydrophobicContact CD2-CB 4.27Å; Y473-F475 HydrophobicContact CE2-CB 4.02Å; F475-Y477 HydrophobicContact CE1-CD1 4.26Å; F475-Y477 HydrophobicContact CE1-CG 4.47Å; F475-Y477 HydrophobicContact CZ-CD1 4.3Å; F475-Y477 HydrophobicContact CZ-CG 4.5Å; F475-T485 HydrophobicContact CD1-CG2 3.66Å; F475-T485 HydrophobicContact CE1-CG2 4.23Å; F475-T485 WeakPolarHBondContact O-CG2 3.43Å; F475-V489 HydrophobicContact CD1-CG1 3.79Å; F475-V489 HydrophobicContact CE1-CG1 3.94Å; F475-D490 HydrophobicContact CB-CB 4.38Å; F475-D490 HydrophobicContact CD2-CB 4.13Å; F475-D490 HydrophobicContact CG-CB 4.1Å; F475-Y493 AromaticContact CE1-CD2 3.91Å; F475-Y493 HydrophobicContact CE1-CD2 3.91Å; F475-Y493 AromaticContact CE1-CE2 3.7Å; F475-Y493 HydrophobicContact CE1-CE2 3.7Å; F475-Y493 HydrophobicContact CE2-CD2 4.08Å; F475-Y493 AromaticContact CZ-CD2 3.27Å; F475-Y493 HydrophobicContact CZ-CD2 3.27Å; F475-Y493 AromaticContact CZ-CE2 3.43Å; F475-Y493 HydrophobicContact CZ-CE2 3.43Å; F475-Y493 VanDerWaalsContact CZ-CE2 3.43Å; F475-Y493 HydrophobicContact CZ-CG 4.22Å; F475-I509 HydrophobicContact CE2-CG2 3.91Å; F475-I509 HydrophobicContact CZ-CG2 3.63Å; F475-I513 HydrophobicContact CD2-CD1 3.86Å; F475-I513 HydrophobicContact CE2-CD1 3.8Å; F475-I550 HydrophobicContact CD2-CB 4.06Å; F475-I550 HydrophobicContact CD2-CD1 4.4Å; F475-I550 HydrophobicContact CD2-CG2 3.85Å; F475-I550 HydrophobicContact CE2-CG2 3.84Å
476D94.6Very high88.6Confident7 Ų736.6 Ų36.64%0.03722%0.223CC..  trans-100.3-19.9-171.2-72.5-42000112.6K371 S474 V478 T485 S549 I550 D551K371-D476 WeakPolarHBondContact CB-OD1 3.47Å; K371-D476 HydrophobicContact CD-CB 4.34Å; K371-D476 VanDerWaalsContact CD-OD1 3.3Å; K371-D476 WeakPolarHBondContact CD-OD1 3.19Å; K371-D476 WeakPolarHBondContact CG-OD1 3.48Å; S474-D476 PolarHBondContact O-N 3.13Å; S474-D476 PolarHBondContact OG-OD1 3.25Å; D476-V478 PolarHBondContact O-N 3.5Å; D476-T485 PolarHBondContact O-OG1 3.1Å; D476-T485 VanDerWaalsContact O-OG1 3.05Å; D476-S549 WeakPolarHBondContact OD2-CB 3.24Å; D476-S549 PolarHBondContact OD2-OG 3.38Å; D476-I550 PolarHBondContact N-O 3.11Å; D476-D551 HydrophobicContact CB-CB 4.19Å
477Y93.6Very high88.4Confident0 Ų036.8 Ų36.80%022%0.217CC..  trans-52.7111.4-178-179.9-104.8000113.3F475 K479 T485 Y493 R505 D506 I509 I550F475-Y477 HydrophobicContact CE1-CD1 4.26Å; F475-Y477 HydrophobicContact CE1-CG 4.47Å; F475-Y477 HydrophobicContact CZ-CD1 4.3Å; F475-Y477 HydrophobicContact CZ-CG 4.5Å; Y477-K479 HydrophobicContact CE1-CB 4.35Å; Y477-T485 VanDerWaalsContact O-CG2 3.32Å; Y477-T485 WeakPolarHBondContact O-CG2 3.27Å; Y477-T485 PolarHBondContact O-OG1 3.33Å; Y477-Y493 HydrophobicContact CD1-CE1 4.49Å; Y477-Y493 HydrophobicContact CD1-CE2 4.01Å; Y477-Y493 AromaticContact CD1-CZ 3.73Å; Y477-Y493 WeakPolarHBondContact CD1-OH 3.17Å; Y477-Y493 HydrophobicContact CE1-CE1 4.15Å; Y477-Y493 HydrophobicContact CE1-CE2 4.39Å; Y477-Y493 AromaticContact CE1-CZ 3.64Å; Y477-Y493 WeakPolarHBondContact CE1-OH 3.08Å; Y477-R505 HydrophobicContact CE2-CG 3.7Å; Y477-R505 VanDerWaalsContact CE2-NE 3.32Å; Y477-R505 WeakPolarHBondContact OH-CD 3.27Å; Y477-R505 VanDerWaalsContact OH-CG 3.3Å; Y477-R505 WeakPolarHBondContact OH-CG 3.47Å; Y477-R505 PolarHBondContact OH-NH1 3.22Å; Y477-D506 WeakPolarHBondContact CE1-OD1 3.28Å; Y477-D506 PolarHBondContact OH-N 3.29Å; Y477-D506 PolarHBondContact OH-OD1 2.79Å; Y477-I509 HydrophobicContact CD1-CB 4.45Å; Y477-I509 HydrophobicContact CD1-CG1 4.22Å; Y477-I509 HydrophobicContact CD1-CG2 4.07Å; Y477-I509 HydrophobicContact CD2-CB 4.5Å; Y477-I509 HydrophobicContact CD2-CD1 3.89Å; Y477-I509 HydrophobicContact CD2-CG1 3.47Å; Y477-I509 VanDerWaalsContact CD2-CG1 3.47Å; Y477-I509 HydrophobicContact CE1-CG1 4.31Å; Y477-I509 HydrophobicContact CE2-CB 4.5Å; Y477-I509 HydrophobicContact CE2-CD1 4.26Å; Y477-I509 HydrophobicContact CE2-CG1 3.47Å; Y477-I509 VanDerWaalsContact CE2-CG1 3.47Å; Y477-I509 HydrophobicContact CG-CB 4.42Å; Y477-I509 HydrophobicContact CG-CD1 4.34Å; Y477-I509 HydrophobicContact CG-CG1 3.81Å; Y477-I509 HydrophobicContact CG-CG2 4.06Å; Y477-I550 PolarHBondContact N-O 3.46Å
478V86.9Confident88.1Confident50 Ų5034.3 Ų34.330%0.30319%0.191SC..PPolyproline II helixtrans-87.4116.3173.5-177.80000108.7D476 F482 T485 R505D476-V478 PolarHBondContact O-N 3.5Å; V478-F482 WeakPolarHBondContact CG1-O 3.33Å; V478-T485 WeakPolarHBondContact CG2-OG1 3.47Å; V478-R505 PolarHBondContact O-NH1 2.92Å
479K82.3Confident87.8Confident24 Ų2434.5 Ų34.510%0.10419%0.19CC..PPolyproline II helixtrans-63.9149177.3-173.8-174.8167.8-143.80111.7Y477 N481 F482 F500Y477-K479 HydrophobicContact CE1-CB 4.35Å; K479-N481 PolarHBondContact O-N 3.02Å; K479-F482 HydrophobicContact CB-CB 4.44Å; K479-F482 HydrophobicContact CB-CD2 3.88Å; K479-F482 HydrophobicContact CB-CG 4.37Å; K479-F482 HydrophobicContact CD-CD2 3.89Å; K479-F482 HydrophobicContact CD-CE2 3.78Å; K479-F482 HydrophobicContact CG-CD2 4.12Å; K479-F482 PolarHBondContact O-N 3.23Å; K479-F500 HydrophobicContact CD-CD2 4.41Å; K479-F500 HydrophobicContact CD-CE1 4.44Å; K479-F500 HydrophobicContact CD-CE2 3.61Å; K479-F500 HydrophobicContact CD-CZ 3.63Å; K479-F500 VanDerWaalsContact CE-CD2 3.48Å; K479-F500 VanDerWaalsContact NZ-CD1 3.28Å; K479-F500 VanDerWaalsContact NZ-CE1 3.26Å
480S77Confident87.5Confident45 Ų4531.4 Ų31.432%0.31517%0.171SC..THydrogen-bonded Turntrans-50.3130.6167.2-52.10000111.8F482 N503S480-F482 VanDerWaalsContact C-N 3.29Å; S480-F482 PolarHBondContact O-N 2.82Å; S480-N503 PolarHBondContact OG-ND2 3.36Å
481N72.9Confident87.3Confident166 Ų16631.6 Ų31.689%0.88817%0.172SC*.THydrogen-bonded Turntrans738.2-176.8-44.5-40.7000115.9K479K479-N481 PolarHBondContact O-N 3.02Å
482F72.9Confident86.9Confident89 Ų8931.7 Ų31.739%0.3917%0.174SC..  trans-106.1140.7167.3-74.2-106.3000109.1V478 K479 S480 S484 P486V478-F482 WeakPolarHBondContact CG1-O 3.33Å; K479-F482 HydrophobicContact CB-CB 4.44Å; K479-F482 HydrophobicContact CB-CD2 3.88Å; K479-F482 HydrophobicContact CB-CG 4.37Å; K479-F482 HydrophobicContact CD-CD2 3.89Å; K479-F482 HydrophobicContact CD-CE2 3.78Å; K479-F482 HydrophobicContact CG-CD2 4.12Å; K479-F482 PolarHBondContact O-N 3.23Å; S480-F482 VanDerWaalsContact C-N 3.29Å; S480-F482 PolarHBondContact O-N 2.82Å; F482-S484 VanDerWaalsContact C-N 3.28Å; F482-P486 HydrophobicContact CD1-CG 4.44Å
483D72Confident86.7Confident126 Ų12631.6 Ų31.667%0.67417%0.174SC*.SBendtrans-82.3-11.7175.3-70-17.5000112K378K378-D483 WeakPolarHBondContact CE-OD2 3.46Å; K378-D483 IonicContact NZ-OD2 3.47Å; K378-D483 PolarHBondContact NZ-OD2 3.35Å
484S80Confident86.6Confident36 Ų3631.4 Ų31.425%0.25217%0.173SC..SBendtrans-154175.3-172.668.60000112.1T375 F482 P486T375-S484 WeakPolarHBondContact CB-OG 3.41Å; T375-S484 WeakPolarHBondContact CG2-OG 3.45Å; T375-S484 PolarHBondContact OG1-OG 3.22Å; F482-S484 VanDerWaalsContact C-N 3.28Å; S484-P486 WeakPolarHBondContact O-CD 3.3Å
485T82.6Confident86.5Confident3 Ų331.4 Ų31.42%0.01817%0.173CC..  trans-108.381.4178.3-47.80000108.6G372 F475 D476 Y477 V478 V489G372-T485 CarbonylContact C-O 3.44Å; G372-T485 WeakPolarHBondContact CA-O 3.23Å; G372-T485 PolarHBondContact N-O 2.9Å; F475-T485 HydrophobicContact CD1-CG2 3.66Å; F475-T485 HydrophobicContact CE1-CG2 4.23Å; F475-T485 WeakPolarHBondContact O-CG2 3.43Å; D476-T485 PolarHBondContact O-OG1 3.1Å; D476-T485 VanDerWaalsContact O-OG1 3.05Å; Y477-T485 VanDerWaalsContact O-CG2 3.32Å; Y477-T485 WeakPolarHBondContact O-CG2 3.27Å; Y477-T485 PolarHBondContact O-OG1 3.33Å; V478-T485 WeakPolarHBondContact CG2-OG1 3.47Å; T485-V489 HydrophobicContact CG2-CG1 3.34Å
486P85.7Confident86.1Confident33 Ų3332.1 Ų32.121%0.21418%0.18CC..BIsolated β-bridgetrans-69.7162.1-171.729.9-37.1000112.3G372 T375 F482 S484 V489G372-P486 WeakPolarHBondContact O-CA 3.16Å; T375-P486 WeakPolarHBondContact OG1-CB 3.48Å; F482-P486 HydrophobicContact CD1-CG 4.44Å; S484-P486 WeakPolarHBondContact O-CD 3.3Å; P486-V489 HydrophobicContact CG-CB 4.37Å; P486-V489 VanDerWaalsContact O-CB 3.26Å; P486-V489 WeakPolarHBondContact O-CB 3.44Å; P486-V489 WeakPolarHBondContact O-CG1 3.29Å; P486-V489 PolarHBondContact O-N 3.46Å
487H88.2Confident85.7Confident40 Ų4033.6 Ų33.619%0.18519%0.188CC..THydrogen-bonded Turntrans-47.8140.2170.4-174.268.5000113.1H214 S215 G372 E373 V489H214-H487 AromaticContact CE1-CE1 3.77Å; H214-H487 AromaticContact CE1-NE2 3.43Å; H214-H487 PolarHBondContact CE1-NE2 2.78Å; H214-H487 AromaticContact NE2-CE1 3.58Å; H214-H487 AromaticContact NE2-NE2 3.69Å; S215-H487 WeakPolarHBondContact CB-NE2 3.37Å; S215-H487 PolarHBondContact OG-NE2 3.36Å; G372-H487 PolarHBondContact O-N 2.95Å; E373-H487 VanDerWaalsContact O-CB 3.27Å; E373-H487 WeakPolarHBondContact O-CB 3.47Å; E373-H487 IonicContact OE2-CE1 3.1Å; E373-H487 IonicContact OE2-CG 2.79Å; E373-H487 IonicContact OE2-ND1 2.65Å; E373-H487 PolarHBondContact OE2-ND1 3.27Å; H487-V489 VanDerWaalsContact C-N 3.28Å; H487-V489 PolarHBondContact O-N 3.19Å
488S87.4Confident85.2Confident8 Ų836.5 Ų36.56%0.05620%0.202CC..THydrogen-bonded Turntrans70.47.6-177.7-25.50000116.5R97 H214 D490 L491 T492R97-S488 PolarHBondContact NH2-OG 3.42Å; H214-S488 VanDerWaalsContact CE1-CB 3.49Å; H214-S488 WeakPolarHBondContact CE1-CB 3.43Å; H214-S488 PolarHBondContact CE1-OG 2.65Å; H214-S488 VanDerWaalsContact NE2-CA 3.29Å; H214-S488 WeakPolarHBondContact NE2-CA 3.3Å; H214-S488 WeakPolarHBondContact NE2-CB 3.41Å; H214-S488 PolarHBondContact NE2-OG 3.02Å; S488-D490 VanDerWaalsContact C-N 3.29Å; S488-D490 VanDerWaalsContact C-OD1 3.26Å; S488-D490 WeakPolarHBondContact CA-OD1 3.18Å; S488-L491 WeakPolarHBondContact O-CB 3.5Å; S488-L491 PolarHBondContact O-N 3.06Å; S488-T492 PolarHBondContact O-N 2.99Å
489V88.9Confident84.5Confident13 Ų1343.3 Ų43.38%0.07923%0.227CC..Hα-helixtrans-72.4-25.6177.974.50000112.3T370 F475 T485 P486 H487 T492 Y493T370-V489 HydrophobicContact CG2-CG1 3.87Å; F475-V489 HydrophobicContact CD1-CG1 3.79Å; F475-V489 HydrophobicContact CE1-CG1 3.94Å; T485-V489 HydrophobicContact CG2-CG1 3.34Å; P486-V489 HydrophobicContact CG-CB 4.37Å; P486-V489 VanDerWaalsContact O-CB 3.26Å; P486-V489 WeakPolarHBondContact O-CB 3.44Å; P486-V489 WeakPolarHBondContact O-CG1 3.29Å; P486-V489 PolarHBondContact O-N 3.46Å; H487-V489 VanDerWaalsContact C-N 3.28Å; H487-V489 PolarHBondContact O-N 3.19Å; V489-T492 WeakPolarHBondContact O-CB 3.37Å; V489-T492 PolarHBondContact O-N 2.87Å; V489-T492 VanDerWaalsContact O-N 3.12Å; V489-Y493 HydrophobicContact CG2-CE2 4.06Å; V489-Y493 WeakPolarHBondContact O-CD2 3.07Å; V489-Y493 WeakPolarHBondContact O-CE2 3.42Å
490D90.1Very high84.4Confident0 Ų044.9 Ų44.90%023%0.234CC..Hα-helixtrans-59.1-44167.150.5-1.4000112.1H214 M240 T370 Y473 F475 S488 T492 Y493 A494 I513H214-D490 IonicContact CD2-OD1 2.65Å; H214-D490 IonicContact NE2-OD1 3.07Å; M240-D490 HydrophobicContact CE-CB 3.84Å; M240-D490 WeakPolarHBondContact CE-OD2 2.93Å; T370-D490 HydrophobicContact CG2-CB 4.46Å; Y473-D490 PolarHBondContact OH-OD2 2.86Å; F475-D490 HydrophobicContact CB-CB 4.38Å; F475-D490 HydrophobicContact CD2-CB 4.13Å; F475-D490 HydrophobicContact CG-CB 4.1Å; S488-D490 VanDerWaalsContact C-N 3.29Å; S488-D490 VanDerWaalsContact C-OD1 3.26Å; S488-D490 WeakPolarHBondContact CA-OD1 3.18Å; D490-T492 PolarHBondContact O-N 3.03Å; D490-Y493 PolarHBondContact O-N 3.01Å; D490-Y493 VanDerWaalsContact O-N 3.13Å; D490-A494 PolarHBondContact O-N 3.25Å; D490-I513 HydrophobicContact CB-CD1 4.12Å
491L92Very high84.7Confident5 Ų548.5 Ų48.53%0.02626%0.256CS..Hα-helixtrans-63.9-21.9173.3-66.6-168.3000113.6F129 H214 M240 S488 Y493 L495 G496 L497F129-L491 HydrophobicContact CE2-CD2 4.22Å; F129-L491 HydrophobicContact CZ-CD1 4.32Å; F129-L491 HydrophobicContact CZ-CD2 4.13Å; H214-L491 HydrophobicContact CB-CD1 3.73Å; H214-L491 HydrophobicContact CB-CD2 4.02Å; H214-L491 HydrophobicContact CB-CG 4.1Å; H214-L491 WeakPolarHBondContact ND1-CD1 3.47Å; M240-L491 HydrophobicContact CE-CD2 3.86Å; M240-L491 HydrophobicContact SD-CD2 3.94Å; S488-L491 WeakPolarHBondContact O-CB 3.5Å; S488-L491 PolarHBondContact O-N 3.06Å; L491-Y493 VanDerWaalsContact C-N 3.29Å; L491-Y493 PolarHBondContact O-N 3.1Å; L491-L495 HydrophobicContact CD2-CD1 4.04Å; L491-L495 CarbonylContact O-C 3.49Å; L491-L495 WeakPolarHBondContact O-CA 3.05Å; L491-L495 PolarHBondContact O-N 3.01Å; L491-G496 PolarHBondContact O-N 3.24Å; L491-L497 HydrophobicContact CB-CD1 3.8Å; L491-L497 HydrophobicContact CD1-CD1 3.86Å
492T90.9Very high85.5Confident14 Ų1441.9 Ų41.99%0.08622%0.219CC..Hα-helixtrans-60.9-44.4173.5-63.10000110.3S488 V489 D490 G496 H498 F500 F502S488-T492 PolarHBondContact O-N 2.99Å; V489-T492 WeakPolarHBondContact O-CB 3.37Å; V489-T492 PolarHBondContact O-N 2.87Å; V489-T492 VanDerWaalsContact O-N 3.12Å; D490-T492 PolarHBondContact O-N 3.03Å; T492-G496 WeakPolarHBondContact O-CA 3.29Å; T492-G496 PolarHBondContact O-N 3.22Å; T492-H498 HydrophobicContact CG2-CB 3.71Å; T492-F500 HydrophobicContact CG2-CE2 4.31Å; T492-F500 HydrophobicContact CG2-CZ 4.04Å; T492-F502 HydrophobicContact CG2-CE1 3.81Å; T492-F502 HydrophobicContact CG2-CZ 3.85Å
493Y93.2Very high86.5Confident0 Ų040.4 Ų40.40%022%0.216CC..Hα-helixtrans-81.6-31.9-178.9-58.4-75.8000112.5F475 Y477 V489 D490 L491 F502 D506 I509 Q510F475-Y493 AromaticContact CE1-CD2 3.91Å; F475-Y493 HydrophobicContact CE1-CD2 3.91Å; F475-Y493 AromaticContact CE1-CE2 3.7Å; F475-Y493 HydrophobicContact CE1-CE2 3.7Å; F475-Y493 HydrophobicContact CE2-CD2 4.08Å; F475-Y493 AromaticContact CZ-CD2 3.27Å; F475-Y493 HydrophobicContact CZ-CD2 3.27Å; F475-Y493 AromaticContact CZ-CE2 3.43Å; F475-Y493 HydrophobicContact CZ-CE2 3.43Å; F475-Y493 VanDerWaalsContact CZ-CE2 3.43Å; F475-Y493 HydrophobicContact CZ-CG 4.22Å; Y477-Y493 HydrophobicContact CD1-CE1 4.49Å; Y477-Y493 HydrophobicContact CD1-CE2 4.01Å; Y477-Y493 AromaticContact CD1-CZ 3.73Å; Y477-Y493 WeakPolarHBondContact CD1-OH 3.17Å; Y477-Y493 HydrophobicContact CE1-CE1 4.15Å; Y477-Y493 HydrophobicContact CE1-CE2 4.39Å; Y477-Y493 AromaticContact CE1-CZ 3.64Å; Y477-Y493 WeakPolarHBondContact CE1-OH 3.08Å; V489-Y493 HydrophobicContact CG2-CE2 4.06Å; V489-Y493 WeakPolarHBondContact O-CD2 3.07Å; V489-Y493 WeakPolarHBondContact O-CE2 3.42Å; D490-Y493 PolarHBondContact O-N 3.01Å; D490-Y493 VanDerWaalsContact O-N 3.13Å; L491-Y493 VanDerWaalsContact C-N 3.29Å; L491-Y493 PolarHBondContact O-N 3.1Å; Y493-F502 HydrophobicContact CD1-CE1 4.37Å; Y493-F502 HydrophobicContact CD1-CE2 4.06Å; Y493-F502 AromaticContact CD1-CZ 3.84Å; Y493-F502 HydrophobicContact CD1-CZ 3.84Å; Y493-F502 HydrophobicContact CE1-CE1 4.19Å; Y493-F502 HydrophobicContact CE1-CZ 4.13Å; Y493-D506 HydrophobicContact CE1-CB 3.94Å; Y493-I509 HydrophobicContact CD1-CG2 4.33Å; Y493-I509 HydrophobicContact CD2-CG2 4.42Å; Y493-I509 HydrophobicContact CG-CG2 4.3Å; Y493-Q510 HydrophobicContact CD1-CB 4.18Å; Y493-Q510 WeakPolarHBondContact O-CG 3.48Å; Y493-Q510 PolarHBondContact O-NE2 3.31Å; Y493-Q510 VanDerWaalsContact O-NE2 3.13Å
494A94.1Very high87.4Confident0 Ų041 Ų410%022%0.215CC..Hα-helixtrans-80.9-42.9179.500000113.7N151 D490 L514 L517N151-A494 PolarHBondContact ND2-O 3.41Å; D490-A494 PolarHBondContact O-N 3.25Å; A494-L514 HydrophobicContact CB-CD2 4.49Å; A494-L517 HydrophobicContact CB-CD1 4.18Å
495L94.3Very high88Confident0 Ų042.7 Ų42.70%022%0.215CC..Hα-helixtrans-125.813.6-169.4-63.4178.3000114.3F129 F143 F152 F159 L491 L497F129-L495 HydrophobicContact CD1-CD1 4.17Å; F129-L495 HydrophobicContact CD2-CD1 4.02Å; F129-L495 HydrophobicContact CE1-CD1 3.75Å; F129-L495 HydrophobicContact CE2-CD1 3.58Å; F129-L495 HydrophobicContact CG-CD1 4.3Å; F129-L495 HydrophobicContact CZ-CD1 3.43Å; F129-L495 VanDerWaalsContact CZ-CD1 3.43Å; F143-L495 HydrophobicContact CD1-CB 3.78Å; F143-L495 HydrophobicContact CD1-CD1 4.02Å; F143-L495 HydrophobicContact CD1-CG 4.44Å; F143-L495 HydrophobicContact CE1-CB 3.85Å; F143-L495 HydrophobicContact CE1-CD1 3.52Å; F143-L495 HydrophobicContact CE1-CG 4.31Å; F143-L495 HydrophobicContact CZ-CD1 3.99Å; F152-L495 HydrophobicContact CD2-CD2 4.41Å; F152-L495 HydrophobicContact CE2-CD2 3.63Å; F152-L495 HydrophobicContact CZ-CD2 4.33Å; F159-L495 HydrophobicContact CE1-CD2 4Å; F159-L495 HydrophobicContact CE2-CD2 4.38Å; F159-L495 HydrophobicContact CZ-CD1 4.48Å; F159-L495 HydrophobicContact CZ-CD2 3.67Å; L491-L495 HydrophobicContact CD2-CD1 4.04Å; L491-L495 CarbonylContact O-C 3.49Å; L491-L495 WeakPolarHBondContact O-CA 3.05Å; L491-L495 PolarHBondContact O-N 3.01Å; L495-L497 VanDerWaalsContact C-N 3.33Å; L495-L497 PolarHBondContact O-N 2.93Å
496G89.3Confident88.5Confident15 Ų1542.7 Ų42.716%0.15522%0.215CC..  trans70.124.5170.200000115L491 T492 H498L491-G496 PolarHBondContact O-N 3.24Å; T492-G496 WeakPolarHBondContact O-CA 3.29Å; T492-G496 PolarHBondContact O-N 3.22Å; G496-H498 VanDerWaalsContact C-CD2 3.42Å; G496-H498 PolarHBondContact O-CD2 3.49Å; G496-H498 PolarHBondContact O-N 3.24Å
497L86.1Confident88.9Confident39 Ų3945.7 Ų45.720%0.20423%0.225CC..  trans-75.259.4-179.5-63.6-177.5000113.1M142 F143 L491 L495M142-L497 HydrophobicContact CE-CD1 3.3Å; M142-L497 HydrophobicContact CE-CD2 3.48Å; M142-L497 VanDerWaalsContact CE-CD2 3.48Å; M142-L497 HydrophobicContact CE-CG 4.02Å; M142-L497 HydrophobicContact CG-CD2 4.09Å; F143-L497 HydrophobicContact CD1-CD2 3.72Å; F143-L497 HydrophobicContact CD1-CG 4.28Å; F143-L497 HydrophobicContact CE1-CD1 3.93Å; F143-L497 HydrophobicContact CE1-CD2 3.72Å; F143-L497 HydrophobicContact CE1-CG 3.98Å; L491-L497 HydrophobicContact CB-CD1 3.8Å; L491-L497 HydrophobicContact CD1-CD1 3.86Å; L495-L497 VanDerWaalsContact C-N 3.33Å; L495-L497 PolarHBondContact O-N 2.93Å
498H81.8Confident89.3Confident61 Ų6149 Ų4928%0.28224%0.239SC..  trans-141.9162.91796097.7000112.9T492 G496 F500 F502T492-H498 HydrophobicContact CG2-CB 3.71Å; G496-H498 VanDerWaalsContact C-CD2 3.42Å; G496-H498 PolarHBondContact O-CD2 3.49Å; G496-H498 PolarHBondContact O-N 3.24Å; H498-F500 HydrophobicContact CB-CD1 4.08Å; H498-F500 HydrophobicContact CB-CD2 4.05Å; H498-F500 HydrophobicContact CB-CE1 3.69Å; H498-F500 HydrophobicContact CB-CE2 3.65Å; H498-F500 HydrophobicContact CB-CG 4.26Å; H498-F500 HydrophobicContact CB-CZ 3.46Å; H498-F500 VanDerWaalsContact CB-CZ 3.46Å; H498-F500 PolarHBondContact CE1-O 3.42Å; H498-F500 VanDerWaalsContact CE1-O 3.27Å; H498-F500 PolarHBondContact ND1-O 2.96Å; H498-F502 AromaticContact CD2-CE1 3.57Å; H498-F502 AromaticContact CD2-CZ 3.46Å; H498-F502 VanDerWaalsContact CD2-CZ 3.46Å; H498-F502 WeakPolarHBondContact CD2-CZ 3.01Å; H498-F502 AromaticContact CE1-CE1 3.71Å; H498-F502 AromaticContact CE1-CZ 3.93Å; H498-F502 AromaticContact CG-CE1 3.74Å; H498-F502 AromaticContact ND1-CE1 3.82Å; H498-F502 AromaticContact NE2-CE1 3.56Å; H498-F502 AromaticContact NE2-CE2 3.84Å; H498-F502 AromaticContact NE2-CZ 3.34Å; H498-F502 VanDerWaalsContact NE2-CZ 3.34Å; H498-F502 WeakPolarHBondContact NE2-CZ 3.28Å
499K73.1Confident89.6Confident192 Ų19248.8 Ų48.884%0.83524%0.237SC*.SBendtrans-113.94.7174.9-64-174179.2-179.20113.5
500F79.1Confident89.9Confident58 Ų5849.9 Ų49.925%0.25424%0.241SC..SBendtrans-118.4150.2-172.346.6-103.3000110.8K479 T492 H498 F502K479-F500 HydrophobicContact CD-CD2 4.41Å; K479-F500 HydrophobicContact CD-CE1 4.44Å; K479-F500 HydrophobicContact CD-CE2 3.61Å; K479-F500 HydrophobicContact CD-CZ 3.63Å; K479-F500 VanDerWaalsContact CE-CD2 3.48Å; K479-F500 VanDerWaalsContact NZ-CD1 3.28Å; K479-F500 VanDerWaalsContact NZ-CE1 3.26Å; T492-F500 HydrophobicContact CG2-CE2 4.31Å; T492-F500 HydrophobicContact CG2-CZ 4.04Å; H498-F500 HydrophobicContact CB-CD1 4.08Å; H498-F500 HydrophobicContact CB-CD2 4.05Å; H498-F500 HydrophobicContact CB-CE1 3.69Å; H498-F500 HydrophobicContact CB-CE2 3.65Å; H498-F500 HydrophobicContact CB-CG 4.26Å; H498-F500 HydrophobicContact CB-CZ 3.46Å; H498-F500 VanDerWaalsContact CB-CZ 3.46Å; H498-F500 PolarHBondContact CE1-O 3.42Å; H498-F500 VanDerWaalsContact CE1-O 3.27Å; H498-F500 PolarHBondContact ND1-O 2.96Å; F500-F502 HydrophobicContact CD2-CD1 4.26Å; F500-F502 HydrophobicContact CD2-CE1 4.36Å; F500-F502 HydrophobicContact CE2-CD1 4.04Å; F500-F502 AromaticContact CE2-CE1 3.78Å; F500-F502 HydrophobicContact CE2-CE1 3.78Å
501P84.6Confident90.2Very high120 Ų12057.3 Ų57.378%0.77927%0.273SS*.  trans-68.8146.6173.729.3-34.3000111.1
502F90.3Very high90.5Very high27 Ų2757.7 Ų57.712%0.11828%0.276CS..  trans-79.5130.8171.3-74.8-10.1000111.1T492 Y493 H498 F500 D506 K507 Q510T492-F502 HydrophobicContact CG2-CE1 3.81Å; T492-F502 HydrophobicContact CG2-CZ 3.85Å; Y493-F502 HydrophobicContact CD1-CE1 4.37Å; Y493-F502 HydrophobicContact CD1-CE2 4.06Å; Y493-F502 AromaticContact CD1-CZ 3.84Å; Y493-F502 HydrophobicContact CD1-CZ 3.84Å; Y493-F502 HydrophobicContact CE1-CE1 4.19Å; Y493-F502 HydrophobicContact CE1-CZ 4.13Å; H498-F502 AromaticContact CD2-CE1 3.57Å; H498-F502 AromaticContact CD2-CZ 3.46Å; H498-F502 VanDerWaalsContact CD2-CZ 3.46Å; H498-F502 WeakPolarHBondContact CD2-CZ 3.01Å; H498-F502 AromaticContact CE1-CE1 3.71Å; H498-F502 AromaticContact CE1-CZ 3.93Å; H498-F502 AromaticContact CG-CE1 3.74Å; H498-F502 AromaticContact ND1-CE1 3.82Å; H498-F502 AromaticContact NE2-CE1 3.56Å; H498-F502 AromaticContact NE2-CE2 3.84Å; H498-F502 AromaticContact NE2-CZ 3.34Å; H498-F502 VanDerWaalsContact NE2-CZ 3.34Å; H498-F502 WeakPolarHBondContact NE2-CZ 3.28Å; F500-F502 HydrophobicContact CD2-CD1 4.26Å; F500-F502 HydrophobicContact CD2-CE1 4.36Å; F500-F502 HydrophobicContact CE2-CD1 4.04Å; F500-F502 AromaticContact CE2-CE1 3.78Å; F500-F502 HydrophobicContact CE2-CE1 3.78Å; F502-D506 HydrophobicContact CB-CB 3.68Å; F502-D506 HydrophobicContact CD1-CB 3.9Å; F502-D506 HydrophobicContact CD2-CB 4.44Å; F502-D506 HydrophobicContact CG-CB 3.77Å; F502-K507 HydrophobicContact CB-CG 3.98Å; F502-Q510 HydrophobicContact CE2-CB 4.32Å; F502-Q510 HydrophobicContact CE2-CG 4.46Å
503N92Very high90.8Very high59 Ų5957.2 Ų57.232%0.31627%0.273SS..  trans-78.5178.1167.368.430.4000110.5S480 R505 D506 K507S480-N503 PolarHBondContact OG-ND2 3.36Å; N503-R505 PolarHBondContact O-N 2.89Å; N503-R505 WeakPolarHBondContact OD1-CA 3.39Å; N503-R505 VanDerWaalsContact OD1-CB 3.3Å; N503-R505 WeakPolarHBondContact OD1-CB 3.45Å; N503-R505 PolarHBondContact OD1-N 3.18Å; N503-D506 PolarHBondContact N-OD2 3.45Å; N503-D506 PolarHBondContact O-N 3.49Å; N503-D506 VanDerWaalsContact OD1-CG 3.24Å; N503-D506 PolarHBondContact OD1-N 2.91Å; N503-D506 PolarHBondContact OD1-OD2 3.44Å; N503-K507 WeakPolarHBondContact O-CG 3.07Å; N503-K507 PolarHBondContact O-N 3.25Å
504E92.2Very high91Very high138 Ų13858 Ų5865%0.64528%0.277SS*.Hα-helixtrans-62-31.3-178.4-65.1-53.5123.800113.7K507 K508E504-K507 IonicContact OE1-NZ 3.92Å; E504-K507 PolarHBondContact OE1-NZ 3.09Å; E504-K508 PolarHBondContact O-N 3.33Å
505R92.8Very high91.2Very high72 Ų7260 Ų6027%0.27229%0.289SS..Hα-helixtrans-69.4-46.4177.2-166-174170.1-115.10.6110.7Y477 V478 N503 K507 K508 I509 D551 D552Y477-R505 HydrophobicContact CE2-CG 3.7Å; Y477-R505 VanDerWaalsContact CE2-NE 3.32Å; Y477-R505 WeakPolarHBondContact OH-CD 3.27Å; Y477-R505 VanDerWaalsContact OH-CG 3.3Å; Y477-R505 WeakPolarHBondContact OH-CG 3.47Å; Y477-R505 PolarHBondContact OH-NH1 3.22Å; V478-R505 PolarHBondContact O-NH1 2.92Å; N503-R505 PolarHBondContact O-N 2.89Å; N503-R505 WeakPolarHBondContact OD1-CA 3.39Å; N503-R505 VanDerWaalsContact OD1-CB 3.3Å; N503-R505 WeakPolarHBondContact OD1-CB 3.45Å; N503-R505 PolarHBondContact OD1-N 3.18Å; R505-K507 PolarHBondContact O-N 3.4Å; R505-K508 WeakPolarHBondContact O-CB 3.48Å; R505-K508 PolarHBondContact O-N 3.09Å; R505-I509 WeakPolarHBondContact O-CG1 3.48Å; R505-I509 PolarHBondContact O-N 2.87Å; R505-I509 VanDerWaalsContact O-N 3.07Å; R505-D551 IonicContact NH2-OD1 3.34Å; R505-D552 WeakPolarHBondContact CD-OD1 3.29Å; R505-D552 WeakPolarHBondContact CG-OD1 3.09Å; R505-D552 IonicContact CZ-OD1 3.69Å; R505-D552 IonicContact CZ-OD2 3.21Å; R505-D552 IonicContact NE-OD1 3.75Å; R505-D552 PolarHBondContact NE-OD1 3.29Å; R505-D552 IonicContact NE-OD2 3.89Å; R505-D552 PolarHBondContact NE-OD2 3.16Å; R505-D552 IonicContact NH2-OD1 2.8Å; R505-D552 IonicContact NH2-OD2 3.99Å; R505-D552 PolarHBondContact NH2-OD2 3.33Å
506D93.4Very high91.4Very high2 Ų260.1 Ų60.11%0.01129%0.29CS..Hα-helixtrans-59.8-44.4175.5-64.2-27.7000111.3Y477 Y493 F502 N503 K508 I509 Q510Y477-D506 WeakPolarHBondContact CE1-OD1 3.28Å; Y477-D506 PolarHBondContact OH-N 3.29Å; Y477-D506 PolarHBondContact OH-OD1 2.79Å; Y493-D506 HydrophobicContact CE1-CB 3.94Å; F502-D506 HydrophobicContact CB-CB 3.68Å; F502-D506 HydrophobicContact CD1-CB 3.9Å; F502-D506 HydrophobicContact CD2-CB 4.44Å; F502-D506 HydrophobicContact CG-CB 3.77Å; N503-D506 PolarHBondContact N-OD2 3.45Å; N503-D506 PolarHBondContact O-N 3.49Å; N503-D506 VanDerWaalsContact OD1-CG 3.24Å; N503-D506 PolarHBondContact OD1-N 2.91Å; N503-D506 PolarHBondContact OD1-OD2 3.44Å; D506-K508 PolarHBondContact O-N 3.45Å; D506-I509 PolarHBondContact O-N 3.19Å; D506-Q510 WeakPolarHBondContact O-CB 3.47Å; D506-Q510 PolarHBondContact O-N 3.19Å
507K94.1Very high91.8Very high96 Ų9659.7 Ų59.742%0.41728%0.284SS..Hα-helixtrans-62.5-40.4176.1-69.7175.5-170.2169.60112.5F502 N503 E504 R505 I509 Q510 K511F502-K507 HydrophobicContact CB-CG 3.98Å; N503-K507 WeakPolarHBondContact O-CG 3.07Å; N503-K507 PolarHBondContact O-N 3.25Å; E504-K507 IonicContact OE1-NZ 3.92Å; E504-K507 PolarHBondContact OE1-NZ 3.09Å; R505-K507 PolarHBondContact O-N 3.4Å; K507-I509 VanDerWaalsContact C-N 3.34Å; K507-Q510 PolarHBondContact O-N 3.22Å; K507-K511 WeakPolarHBondContact O-CB 3.32Å; K507-K511 PolarHBondContact O-N 2.83Å
508K94.8Very high92.4Very high111 Ų11158.2 Ų58.248%0.48328%0.276SS..Hα-helixtrans-61.8-44.7176.4-173.1-174.1177.5-161.90110.8E504 R505 D506 K511 V512 D552E504-K508 PolarHBondContact O-N 3.33Å; R505-K508 WeakPolarHBondContact O-CB 3.48Å; R505-K508 PolarHBondContact O-N 3.09Å; D506-K508 PolarHBondContact O-N 3.45Å; K508-K511 PolarHBondContact O-N 2.65Å; K508-V512 WeakPolarHBondContact O-CG2 3.37Å; K508-V512 PolarHBondContact O-N 3.11Å; K508-D552 PolarHBondContact NZ-O 3.47Å
509I95Very high93.2Very high2 Ų256.8 Ų56.81%0.0127%0.271CS..Hα-helixtrans-67.1-42.5177.7-67.3-58.5000112F475 Y477 Y493 R505 D506 K507 K511 V512 I513 D551F475-I509 HydrophobicContact CE2-CG2 3.91Å; F475-I509 HydrophobicContact CZ-CG2 3.63Å; Y477-I509 HydrophobicContact CD1-CB 4.45Å; Y477-I509 HydrophobicContact CD1-CG1 4.22Å; Y477-I509 HydrophobicContact CD1-CG2 4.07Å; Y477-I509 HydrophobicContact CD2-CB 4.5Å; Y477-I509 HydrophobicContact CD2-CD1 3.89Å; Y477-I509 HydrophobicContact CD2-CG1 3.47Å; Y477-I509 VanDerWaalsContact CD2-CG1 3.47Å; Y477-I509 HydrophobicContact CE1-CG1 4.31Å; Y477-I509 HydrophobicContact CE2-CB 4.5Å; Y477-I509 HydrophobicContact CE2-CD1 4.26Å; Y477-I509 HydrophobicContact CE2-CG1 3.47Å; Y477-I509 VanDerWaalsContact CE2-CG1 3.47Å; Y477-I509 HydrophobicContact CG-CB 4.42Å; Y477-I509 HydrophobicContact CG-CD1 4.34Å; Y477-I509 HydrophobicContact CG-CG1 3.81Å; Y477-I509 HydrophobicContact CG-CG2 4.06Å; Y493-I509 HydrophobicContact CD1-CG2 4.33Å; Y493-I509 HydrophobicContact CD2-CG2 4.42Å; Y493-I509 HydrophobicContact CG-CG2 4.3Å; R505-I509 WeakPolarHBondContact O-CG1 3.48Å; R505-I509 PolarHBondContact O-N 2.87Å; R505-I509 VanDerWaalsContact O-N 3.07Å; D506-I509 PolarHBondContact O-N 3.19Å; K507-I509 VanDerWaalsContact C-N 3.34Å; I509-K511 VanDerWaalsContact C-N 3.31Å; I509-K511 PolarHBondContact O-N 2.86Å; I509-V512 PolarHBondContact O-N 2.95Å; I509-V512 VanDerWaalsContact O-N 3.12Å; I509-I513 WeakPolarHBondContact O-CG2 3.26Å; I509-I513 PolarHBondContact O-N 3.46Å; I509-D551 VanDerWaalsContact CD1-O 3.26Å; I509-D551 WeakPolarHBondContact CD1-O 3.43Å
510Q95.8Very high94.5Very high37 Ų3747.7 Ų47.717%0.17323%0.231CC..Hα-helixtrans-53.8-49.5172.1173.6171.751.100111.3Y493 F502 D506 K507 V512 I513 L514Y493-Q510 HydrophobicContact CD1-CB 4.18Å; Y493-Q510 WeakPolarHBondContact O-CG 3.48Å; Y493-Q510 PolarHBondContact O-NE2 3.31Å; Y493-Q510 VanDerWaalsContact O-NE2 3.13Å; F502-Q510 HydrophobicContact CE2-CB 4.32Å; F502-Q510 HydrophobicContact CE2-CG 4.46Å; D506-Q510 WeakPolarHBondContact O-CB 3.47Å; D506-Q510 PolarHBondContact O-N 3.19Å; K507-Q510 PolarHBondContact O-N 3.22Å; Q510-V512 VanDerWaalsContact C-N 3.3Å; Q510-V512 PolarHBondContact O-N 2.72Å; Q510-I513 WeakPolarHBondContact O-CG2 3Å; Q510-I513 PolarHBondContact O-N 2.83Å; Q510-L514 HydrophobicContact CG-CD1 3.57Å; Q510-L514 HydrophobicContact CG-CG 4.24Å; Q510-L514 WeakPolarHBondContact O-CB 3.33Å; Q510-L514 VanDerWaalsContact O-CG 3.25Å; Q510-L514 WeakPolarHBondContact O-CG 3.2Å; Q510-L514 PolarHBondContact O-N 2.77Å
511K96.3Very high95.4Very high155 Ų15545 Ų4567%0.67422%0.22SC*.Hα-helixtrans-58-43.5177.1-174.7175-177.91740111.7K507 K508 I509 T515K507-K511 WeakPolarHBondContact O-CB 3.32Å; K507-K511 PolarHBondContact O-N 2.83Å; K508-K511 PolarHBondContact O-N 2.65Å; I509-K511 VanDerWaalsContact C-N 3.31Å; I509-K511 PolarHBondContact O-N 2.86Å; K511-T515 WeakPolarHBondContact O-CB 3.34Å; K511-T515 PolarHBondContact O-N 3.06Å; K511-T515 PolarHBondContact O-OG1 2.96Å
512V97.2Very high96.1Very high13 Ų1341.9 Ų41.98%0.07919%0.194CC..Hα-helixtrans-63.5-54.1-180170.30000111.2K508 I509 Q510 L514 T515 L516 L554K508-V512 WeakPolarHBondContact O-CG2 3.37Å; K508-V512 PolarHBondContact O-N 3.11Å; I509-V512 PolarHBondContact O-N 2.95Å; I509-V512 VanDerWaalsContact O-N 3.12Å; Q510-V512 VanDerWaalsContact C-N 3.3Å; Q510-V512 PolarHBondContact O-N 2.72Å; V512-L514 PolarHBondContact O-N 3.11Å; V512-T515 PolarHBondContact O-N 3.46Å; V512-L516 HydrophobicContact CG1-CD1 3.78Å; V512-L516 HydrophobicContact CG1-CG 4.44Å; V512-L516 VanDerWaalsContact O-CG 3.24Å; V512-L516 WeakPolarHBondContact O-CG 3.42Å; V512-L516 PolarHBondContact O-N 3.23Å; V512-L554 HydrophobicContact CG1-CD1 3.95Å; V512-L554 HydrophobicContact CG1-CD2 4.01Å
513I96.6Very high96.4Very high4 Ų444.9 Ų44.92%0.02121%0.211CC..Hα-helixtrans-63.4-41.2-177.1-169.4172.2000111.9F475 D490 I509 Q510 L516 L517F475-I513 HydrophobicContact CD2-CD1 3.86Å; F475-I513 HydrophobicContact CE2-CD1 3.8Å; D490-I513 HydrophobicContact CB-CD1 4.12Å; I509-I513 WeakPolarHBondContact O-CG2 3.26Å; I509-I513 PolarHBondContact O-N 3.46Å; Q510-I513 WeakPolarHBondContact O-CG2 3Å; Q510-I513 PolarHBondContact O-N 2.83Å; I513-L516 PolarHBondContact O-N 2.7Å; I513-L517 HydrophobicContact CG1-CD1 3.99Å; I513-L517 HydrophobicContact CG1-CG 4.34Å; I513-L517 VanDerWaalsContact O-CG 3.28Å; I513-L517 WeakPolarHBondContact O-CG 3.44Å; I513-L517 PolarHBondContact O-N 2.99Å
514L98Very high96.7Very high16 Ų1644.2 Ų44.28%0.08421%0.211CC..Hα-helixtrans-62.5-48176.3-70.8174.8000111.4N151 F152 A494 Q510 V512 L516 L517 I518N151-L514 HydrophobicContact CB-CD1 3.89Å; N151-L514 HydrophobicContact CB-CD2 3.71Å; N151-L514 HydrophobicContact CB-CG 4.47Å; N151-L514 VanDerWaalsContact CG-CD1 3.44Å; N151-L514 WeakPolarHBondContact OD1-CD1 3.48Å; F152-L514 HydrophobicContact CE2-CD2 4.31Å; F152-L514 HydrophobicContact CZ-CD2 4.2Å; A494-L514 HydrophobicContact CB-CD2 4.49Å; Q510-L514 HydrophobicContact CG-CD1 3.57Å; Q510-L514 HydrophobicContact CG-CG 4.24Å; Q510-L514 WeakPolarHBondContact O-CB 3.33Å; Q510-L514 VanDerWaalsContact O-CG 3.25Å; Q510-L514 WeakPolarHBondContact O-CG 3.2Å; Q510-L514 PolarHBondContact O-N 2.77Å; V512-L514 PolarHBondContact O-N 3.11Å; L514-L516 VanDerWaalsContact C-N 3.29Å; L514-L516 PolarHBondContact O-N 2.68Å; L514-L517 PolarHBondContact O-N 3.43Å; L514-I518 HydrophobicContact CB-CD1 4.17Å; L514-I518 WeakPolarHBondContact O-CB 3.34Å; L514-I518 VanDerWaalsContact O-CD1 3.3Å; L514-I518 WeakPolarHBondContact O-CD1 3.31Å; L514-I518 WeakPolarHBondContact O-CG1 3.06Å; L514-I518 PolarHBondContact O-N 2.85Å
515T98.2Very high97Very high43 Ų4339.9 Ų39.926%0.26419%0.192SC..Hα-helixtrans-56.4-44.9178.5-52.30000111.2K511 V512 N519 I531K511-T515 WeakPolarHBondContact O-CB 3.34Å; K511-T515 PolarHBondContact O-N 3.06Å; K511-T515 PolarHBondContact O-OG1 2.96Å; V512-T515 PolarHBondContact O-N 3.46Å; T515-N519 VanDerWaalsContact O-CB 3.22Å; T515-N519 WeakPolarHBondContact O-CB 3.06Å; T515-N519 PolarHBondContact O-N 3.41Å; T515-N519 PolarHBondContact O-ND2 3.43Å; T515-I531 HydrophobicContact CG2-CD1 3.52Å; T515-I531 HydrophobicContact CG2-CG1 4.31Å
516L98.5Very high97.3Very high2 Ų236.4 Ų36.41%0.0118%0.179CC..Hα-helixtrans-62.4-46.7179.1-65.8164.6000111.8V512 I513 L514 F520 P526 T527 I531 W536 L548 I550V512-L516 HydrophobicContact CG1-CD1 3.78Å; V512-L516 HydrophobicContact CG1-CG 4.44Å; V512-L516 VanDerWaalsContact O-CG 3.24Å; V512-L516 WeakPolarHBondContact O-CG 3.42Å; V512-L516 PolarHBondContact O-N 3.23Å; I513-L516 PolarHBondContact O-N 2.7Å; L514-L516 VanDerWaalsContact C-N 3.29Å; L514-L516 PolarHBondContact O-N 2.68Å; L516-F520 PolarHBondContact O-N 3.21Å; L516-F520 VanDerWaalsContact O-N 3.13Å; L516-P526 HydrophobicContact CB-CB 4.35Å; L516-P526 HydrophobicContact CD2-CB 4.26Å; L516-P526 WeakPolarHBondContact O-CA 3.41Å; L516-P526 WeakPolarHBondContact O-CB 3.26Å; L516-T527 HydrophobicContact CD2-CG2 3.71Å; L516-I531 HydrophobicContact CD2-CD1 3.63Å; L516-I531 HydrophobicContact CG-CD1 4.08Å; L516-W536 HydrophobicContact CB-CZ3 4.07Å; L516-W536 HydrophobicContact CD1-CE3 4.44Å; L516-W536 HydrophobicContact CD1-CZ3 4.1Å; L516-W536 HydrophobicContact CD2-CE3 3.75Å; L516-W536 HydrophobicContact CD2-CZ3 4.1Å; L516-W536 HydrophobicContact CG-CE3 4.46Å; L516-W536 HydrophobicContact CG-CZ3 4.32Å; L516-L548 HydrophobicContact CD1-CD2 3.86Å; L516-L548 HydrophobicContact CD2-CD2 4.15Å; L516-I550 HydrophobicContact CD1-CD1 4.09Å; L516-I550 HydrophobicContact CD1-CG1 4.46Å
517L98.6Very high97.5Very high6 Ų636.6 Ų36.63%0.03118%0.18CC..Hα-helixtrans-66.3-46.5-179.8-68.2173.5000111.8M212 I238 L366 A494 I513 L514 F520 V521M212-L517 HydrophobicContact CE-CD1 4.1Å; M212-L517 HydrophobicContact CE-CD2 4.49Å; I238-L517 HydrophobicContact CD1-CD2 4.24Å; I238-L517 HydrophobicContact CG2-CD2 4.11Å; L366-L517 HydrophobicContact CD1-CD2 4.43Å; L366-L517 HydrophobicContact CD2-CD2 4.28Å; A494-L517 HydrophobicContact CB-CD1 4.18Å; I513-L517 HydrophobicContact CG1-CD1 3.99Å; I513-L517 HydrophobicContact CG1-CG 4.34Å; I513-L517 VanDerWaalsContact O-CG 3.28Å; I513-L517 WeakPolarHBondContact O-CG 3.44Å; I513-L517 PolarHBondContact O-N 2.99Å; L514-L517 PolarHBondContact O-N 3.43Å; L517-F520 PolarHBondContact O-N 3.05Å; L517-V521 VanDerWaalsContact O-CG2 3.3Å; L517-V521 WeakPolarHBondContact O-CG2 3.34Å; L517-V521 PolarHBondContact O-N 3.22Å
518I98.7Very high97.7Very high8 Ų835 Ų354%0.04118%0.18CC..Hα-helixtrans-62.8-44.7179.5-66.4158.1000110.7N151 E155 V157 L514 F520 V521 K522N151-I518 WeakPolarHBondContact O-CD1 3.18Å; E155-I518 HydrophobicContact CB-CD1 3.83Å; E155-I518 HydrophobicContact CB-CG1 4.38Å; E155-I518 HydrophobicContact CB-CG2 4.18Å; E155-I518 HydrophobicContact CG-CD1 3.69Å; V157-I518 HydrophobicContact CG2-CG2 4.25Å; L514-I518 HydrophobicContact CB-CD1 4.17Å; L514-I518 WeakPolarHBondContact O-CB 3.34Å; L514-I518 VanDerWaalsContact O-CD1 3.3Å; L514-I518 WeakPolarHBondContact O-CD1 3.31Å; L514-I518 WeakPolarHBondContact O-CG1 3.06Å; L514-I518 PolarHBondContact O-N 2.85Å; I518-F520 VanDerWaalsContact C-N 3.31Å; I518-F520 PolarHBondContact O-N 3.38Å; I518-V521 PolarHBondContact O-N 3.39Å; I518-K522 HydrophobicContact CG2-CD 3.96Å; I518-K522 HydrophobicContact CG2-CG 4.43Å; I518-K522 WeakPolarHBondContact O-CB 3.4Å; I518-K522 WeakPolarHBondContact O-CG 3.02Å; I518-K522 PolarHBondContact O-N 3.48Å
519N98.7Very high97.8Very high32 Ų3236 Ų3617%0.17119%0.189CC..Hα-helixtrans-59.9-43.7177.9-78.3-15.3000111.5T515 K522 N523 D525 P526 P528T515-N519 VanDerWaalsContact O-CB 3.22Å; T515-N519 WeakPolarHBondContact O-CB 3.06Å; T515-N519 PolarHBondContact O-N 3.41Å; T515-N519 PolarHBondContact O-ND2 3.43Å; N519-K522 PolarHBondContact O-N 2.95Å; N519-N523 WeakPolarHBondContact O-CB 3.47Å; N519-N523 PolarHBondContact O-N 3.26Å; N519-N523 PolarHBondContact O-ND2 3.35Å; N519-N523 VanDerWaalsContact O-ND2 3.12Å; N519-D525 CarbonylContact C-O 3.13Å; N519-D525 WeakPolarHBondContact CB-O 3.44Å; N519-D525 VanDerWaalsContact O-O 3.07Å; N519-P526 VanDerWaalsContact CB-O 3.3Å; N519-P526 WeakPolarHBondContact CB-O 3.01Å; N519-P526 PolarHBondContact ND2-O 3.5Å; N519-P526 VanDerWaalsContact ND2-O 3.09Å; N519-P528 HydrophobicContact CB-CG 4.3Å
520F98.8Very high97.9Very high0 Ų039.2 Ų39.20%021%0.21CC..Hα-helixtrans-62.8-46.8176.3-179.8-99.1000111.5Q236 I238 P364 L366 Y471 L516 L517 I518 K522 N523 S524 D525 P526Q236-F520 HydrophobicContact CB-CE1 4.36Å; Q236-F520 HydrophobicContact CB-CZ 4.3Å; Q236-F520 HydrophobicContact CG-CE1 4.33Å; Q236-F520 PolarHBondContact NE2-O 2.81Å; Q236-F520 VanDerWaalsContact OE1-CE1 3.24Å; Q236-F520 VanDerWaalsContact OE1-CZ 3.27Å; Q236-F520 PolarHBondContact OE1-O 3.46Å; I238-F520 HydrophobicContact CD1-CD1 3.85Å; I238-F520 HydrophobicContact CD1-CE1 4.29Å; I238-F520 HydrophobicContact CG1-CD1 3.67Å; I238-F520 HydrophobicContact CG1-CE1 3.63Å; P364-F520 HydrophobicContact CB-CE2 3.99Å; P364-F520 HydrophobicContact CB-CZ 3.92Å; L366-F520 HydrophobicContact CB-CD1 3.94Å; L366-F520 HydrophobicContact CB-CD2 4.17Å; L366-F520 HydrophobicContact CB-CE1 3.74Å; L366-F520 HydrophobicContact CB-CE2 4Å; L366-F520 HydrophobicContact CB-CG 4.14Å; L366-F520 HydrophobicContact CB-CZ 3.77Å; L366-F520 HydrophobicContact CD1-CB 3.84Å; L366-F520 HydrophobicContact CD1-CD1 4.07Å; L366-F520 HydrophobicContact CD1-CD2 4.09Å; L366-F520 HydrophobicContact CD1-CG 3.72Å; Y471-F520 HydrophobicContact CD2-CD2 4.02Å; Y471-F520 AromaticContact CD2-CE2 3.84Å; Y471-F520 HydrophobicContact CD2-CE2 3.84Å; Y471-F520 HydrophobicContact CE2-CD2 4.24Å; Y471-F520 HydrophobicContact CE2-CE2 4.13Å; L516-F520 PolarHBondContact O-N 3.21Å; L516-F520 VanDerWaalsContact O-N 3.13Å; L517-F520 PolarHBondContact O-N 3.05Å; I518-F520 VanDerWaalsContact C-N 3.31Å; I518-F520 PolarHBondContact O-N 3.38Å; F520-K522 PolarHBondContact O-N 3.4Å; F520-N523 PolarHBondContact O-N 3.14Å; F520-S524 VanDerWaalsContact O-CA 3.25Å; F520-S524 WeakPolarHBondContact O-CA 3.49Å; F520-S524 PolarHBondContact O-N 3.31Å; F520-D525 PolarHBondContact N-O 3.31Å; F520-P526 HydrophobicContact CB-CB 4.21Å
521V98.8Very high97.9Very high3 Ų338.6 Ų38.62%0.01821%0.208CC..Hα-helixtrans-57-39.5176.2169.40000111.9P125 V127 V157 T210 Q236 I238 L517 I518P125-V521 HydrophobicContact CB-CG1 3.96Å; P125-V521 HydrophobicContact CG-CG1 4.13Å; V127-V521 HydrophobicContact CG2-CB 4.27Å; V127-V521 HydrophobicContact CG2-CG1 3.66Å; V127-V521 HydrophobicContact CG2-CG2 3.53Å; V157-V521 HydrophobicContact CG1-CG1 3.91Å; V157-V521 HydrophobicContact CG2-CG1 4.12Å; T210-V521 HydrophobicContact CG2-CG2 4.23Å; Q236-V521 PolarHBondContact NE2-O 3.1Å; Q236-V521 VanDerWaalsContact NE2-O 3.08Å; I238-V521 HydrophobicContact CD1-CG2 3.86Å; L517-V521 VanDerWaalsContact O-CG2 3.3Å; L517-V521 WeakPolarHBondContact O-CG2 3.34Å; L517-V521 PolarHBondContact O-N 3.22Å; I518-V521 PolarHBondContact O-N 3.39Å
522K98.4Very high97.7Very high54 Ų5435.5 Ų35.524%0.23521%0.206CC..Hα-helixtrans-78.3-39.6-178.2-74.1-178.9176-176.40113.7P125 E155 D156 I518 N519 F520P125-K522 HydrophobicContact CG-CG 4.03Å; E155-K522 WeakPolarHBondContact O-CE 3.17Å; E155-K522 PolarHBondContact O-NZ 3Å; D156-K522 IonicContact OD2-NZ 2.77Å; I518-K522 HydrophobicContact CG2-CD 3.96Å; I518-K522 HydrophobicContact CG2-CG 4.43Å; I518-K522 WeakPolarHBondContact O-CB 3.4Å; I518-K522 WeakPolarHBondContact O-CG 3.02Å; I518-K522 PolarHBondContact O-N 3.48Å; N519-K522 PolarHBondContact O-N 2.95Å; F520-K522 PolarHBondContact O-N 3.4Å
523N98Very high97.6Very high89 Ų8938.4 Ų38.448%0.47624%0.238SC..Hα-helixtrans-127.7-1.7-162.6-51.6-66.8000114.5N519 F520 D525N519-N523 WeakPolarHBondContact O-CB 3.47Å; N519-N523 PolarHBondContact O-N 3.26Å; N519-N523 PolarHBondContact O-ND2 3.35Å; N519-N523 VanDerWaalsContact O-ND2 3.12Å; F520-N523 PolarHBondContact O-N 3.14Å; N523-D525 PolarHBondContact O-N 3.5Å; N523-D525 VanDerWaalsContact O-N 3.1Å
524S98.4Very high97.6Very high45 Ų4539.3 Ų39.332%0.31524%0.244SC..SBendtrans58.217.6-170-52.40000113.8Q236 Y471 F520Q236-S524 PolarHBondContact OE1-OG 3.45Å; Y471-S524 WeakPolarHBondContact CE2-O 2.95Å; F520-S524 VanDerWaalsContact O-CA 3.25Å; F520-S524 WeakPolarHBondContact O-CA 3.49Å; F520-S524 PolarHBondContact O-N 3.31Å
525D98.5Very high97.6Very high47 Ų4741.9 Ų41.925%0.25126%0.26SS..  trans-138.9121.3177.9179.1-9.6000107.5N519 F520 N523 T527 P528N519-D525 CarbonylContact C-O 3.13Å; N519-D525 WeakPolarHBondContact CB-O 3.44Å; N519-D525 VanDerWaalsContact O-O 3.07Å; F520-D525 PolarHBondContact N-O 3.31Å; N523-D525 PolarHBondContact O-N 3.5Å; N523-D525 VanDerWaalsContact O-N 3.1Å; D525-T527 VanDerWaalsContact C-N 3.29Å; D525-T527 PolarHBondContact O-N 2.95Å; D525-T527 VanDerWaalsContact OD1-C 3.28Å; D525-T527 WeakPolarHBondContact OD1-CA 3.42Å; D525-T527 PolarHBondContact OD1-N 3.13Å; D525-P528 WeakPolarHBondContact O-CD 3.43Å
526P98.5Very high97.6Very high0 Ų040.1 Ų40.10%025%0.249CC..SBendtrans-74.8-16.6179.631.1-34.7000113.5L366 Y471 L516 N519 F520 W536L366-P526 HydrophobicContact CD1-CB 4.39Å; Y471-P526 HydrophobicContact CD1-CG 3.64Å; Y471-P526 HydrophobicContact CD2-CG 4.25Å; Y471-P526 VanDerWaalsContact CE1-CD 3.49Å; Y471-P526 HydrophobicContact CE1-CG 3.84Å; Y471-P526 HydrophobicContact CE2-CG 4.41Å; Y471-P526 HydrophobicContact CG-CG 3.85Å; L516-P526 HydrophobicContact CB-CB 4.35Å; L516-P526 HydrophobicContact CD2-CB 4.26Å; L516-P526 WeakPolarHBondContact O-CA 3.41Å; L516-P526 WeakPolarHBondContact O-CB 3.26Å; N519-P526 VanDerWaalsContact CB-O 3.3Å; N519-P526 WeakPolarHBondContact CB-O 3.01Å; N519-P526 PolarHBondContact ND2-O 3.5Å; N519-P526 VanDerWaalsContact ND2-O 3.09Å; F520-P526 HydrophobicContact CB-CB 4.21Å; P526-W536 HydrophobicContact CB-CD2 4.36Å; P526-W536 HydrophobicContact CB-CE3 3.49Å; P526-W536 VanDerWaalsContact CB-CE3 3.49Å; P526-W536 HydrophobicContact CB-CZ3 3.92Å; P526-W536 HydrophobicContact CG-CB 3.96Å; P526-W536 HydrophobicContact CG-CD2 3.7Å; P526-W536 HydrophobicContact CG-CE3 3.33Å; P526-W536 HydrophobicContact CG-CG 3.99Å; P526-W536 HydrophobicContact CG-CZ3 4.08Å
527T98.2Very high97.4Very high5 Ų546.6 Ų46.63%0.03128%0.277CS..  trans-134.458.1-178.8550000112.7L516 D525 I529 I531 W536L516-T527 HydrophobicContact CD2-CG2 3.71Å; D525-T527 VanDerWaalsContact C-N 3.29Å; D525-T527 PolarHBondContact O-N 2.95Å; D525-T527 VanDerWaalsContact OD1-C 3.28Å; D525-T527 WeakPolarHBondContact OD1-CA 3.42Å; D525-T527 PolarHBondContact OD1-N 3.13Å; T527-I529 CarbonylContact C-O 3.46Å; T527-I529 PolarHBondContact O-N 2.98Å; T527-I529 VanDerWaalsContact O-N 3.13Å; T527-I531 HydrophobicContact CG2-CD1 4.17Å; T527-I531 HydrophobicContact CG2-CG1 4.33Å; T527-W536 HydrophobicContact CG2-CB 3.82Å; T527-W536 PolarHBondContact OG1-N 3.44Å
528P97.6Very high97.3Very high64 Ų6448.3 Ų48.342%0.41629%0.288SS..SBendtrans-59.8-27.3174.728.1-35.8000111.1N519 D525N519-P528 HydrophobicContact CB-CG 4.3Å; D525-P528 WeakPolarHBondContact O-CD 3.43Å
529I96.4Very high97Very high130 Ų13048.2 Ų48.267%0.66729%0.288SS*.SBendtrans-121.9136.2164.4-57.4170.6000106.8T527 I531T527-I529 CarbonylContact C-O 3.46Å; T527-I529 PolarHBondContact O-N 2.98Å; T527-I529 VanDerWaalsContact O-N 3.13Å; I529-I531 PolarHBondContact O-N 2.79Å
530P97.5Very high96Very high71 Ų7150.4 Ų50.446%0.46130%0.302SS..  trans-56.4134.6179-24.833000112.8V534P530-V534 WeakPolarHBondContact CA-O 3.39Å
531I96Very high94.7Very high24 Ų2453.1 Ų53.112%0.12333%0.325CS..BIsolated β-bridgetrans-102.2120.9178.7-63.1172.7000108.2T515 L516 T527 I529 G533 V534 L554T515-I531 HydrophobicContact CG2-CD1 3.52Å; T515-I531 HydrophobicContact CG2-CG1 4.31Å; L516-I531 HydrophobicContact CD2-CD1 3.63Å; L516-I531 HydrophobicContact CG-CD1 4.08Å; T527-I531 HydrophobicContact CG2-CD1 4.17Å; T527-I531 HydrophobicContact CG2-CG1 4.33Å; I529-I531 PolarHBondContact O-N 2.79Å; I531-G533 PolarHBondContact O-N 3.26Å; I531-V534 PolarHBondContact N-O 2.8Å; I531-V534 WeakPolarHBondContact O-CB 3.29Å; I531-V534 PolarHBondContact O-N 3.19Å; I531-L554 HydrophobicContact CB-CD2 4.27Å; I531-L554 HydrophobicContact CG2-CD2 4.06Å
532S92.4Very high92.6Very high90 Ų9057 Ų5763%0.62935%0.35SS*.THydrogen-bonded Turntrans53.833.9-173.3-530000113.2V534S532-V534 PolarHBondContact O-N 3.05Å
533G94.6Very high90.7Very high73 Ų7360.2 Ų60.275%0.75337%0.37SS*.THydrogen-bonded Turntrans76.55.3-17700000114.8I531I531-G533 PolarHBondContact O-N 3.26Å
534V97.6Very high89.1Confident24 Ų2456 Ų5615%0.14535%0.348CS..BIsolated β-bridgetrans-105.4128.4-180-178.30000110.4P530 I531 S532 L548 L554 M556P530-V534 WeakPolarHBondContact CA-O 3.39Å; I531-V534 PolarHBondContact N-O 2.8Å; I531-V534 WeakPolarHBondContact O-CB 3.29Å; I531-V534 PolarHBondContact O-N 3.19Å; S532-V534 PolarHBondContact O-N 3.05Å; V534-L548 HydrophobicContact CG1-CD1 4.02Å; V534-L554 HydrophobicContact CB-CD2 4.27Å; V534-L554 HydrophobicContact CB-CG 4.44Å; V534-L554 WeakPolarHBondContact CG2-O 3.36Å; V534-M556 HydrophobicContact CG1-CG 4.28Å
535T97.7Very high88.3Confident69 Ų6954.1 Ų54.142%0.42334%0.335SS..  trans-98.9125165.5-56.80000108.2K537T535-K537 PolarHBondContact O-N 2.95Å
536W97Very high88Confident6 Ų653 Ų532%0.02333%0.329CS..  trans-76.1105.4175.9-168.8-15000108.6L366 Y471 L472 Y473 L516 P526 T527 L548 M556L366-W536 HydrophobicContact CD1-CH2 4.08Å; L366-W536 HydrophobicContact CD1-CZ3 4.14Å; L366-W536 HydrophobicContact CD2-CH2 4.19Å; L366-W536 HydrophobicContact CG-CH2 4.1Å; Y471-W536 HydrophobicContact CD1-CB 4.42Å; Y471-W536 AromaticContact CD1-CD1 3.76Å; Y471-W536 HydrophobicContact CD1-CD2 4.17Å; Y471-W536 AromaticContact CD1-CG 3.86Å; Y471-W536 HydrophobicContact CD1-CG 3.86Å; Y471-W536 WeakPolarHBondContact CE1-O 3.49Å; L472-W536 WeakPolarHBondContact O-CZ2 3.41Å; L472-W536 PolarHBondContact O-NE1 3.42Å; Y473-W536 AromaticContact CD1-CH2 3.89Å; Y473-W536 HydrophobicContact CD1-CH2 3.89Å; Y473-W536 HydrophobicContact CD1-CZ2 4.2Å; Y473-W536 HydrophobicContact CG-CH2 4.08Å; Y473-W536 HydrophobicContact CG-CZ2 4.31Å; L516-W536 HydrophobicContact CB-CZ3 4.07Å; L516-W536 HydrophobicContact CD1-CE3 4.44Å; L516-W536 HydrophobicContact CD1-CZ3 4.1Å; L516-W536 HydrophobicContact CD2-CE3 3.75Å; L516-W536 HydrophobicContact CD2-CZ3 4.1Å; L516-W536 HydrophobicContact CG-CE3 4.46Å; L516-W536 HydrophobicContact CG-CZ3 4.32Å; P526-W536 HydrophobicContact CB-CD2 4.36Å; P526-W536 HydrophobicContact CB-CE3 3.49Å; P526-W536 VanDerWaalsContact CB-CE3 3.49Å; P526-W536 HydrophobicContact CB-CZ3 3.92Å; P526-W536 HydrophobicContact CG-CB 3.96Å; P526-W536 HydrophobicContact CG-CD2 3.7Å; P526-W536 HydrophobicContact CG-CE3 3.33Å; P526-W536 HydrophobicContact CG-CG 3.99Å; P526-W536 HydrophobicContact CG-CZ3 4.08Å; T527-W536 HydrophobicContact CG2-CB 3.82Å; T527-W536 PolarHBondContact OG1-N 3.44Å; W536-L548 HydrophobicContact CB-CD2 4.31Å; W536-L548 HydrophobicContact CD2-CB 3.79Å; W536-L548 HydrophobicContact CD2-CD2 3.36Å; W536-L548 HydrophobicContact CD2-CG 4.19Å; W536-L548 VanDerWaalsContact CE2-CB 3.49Å; W536-L548 HydrophobicContact CE3-CB 4.43Å; W536-L548 HydrophobicContact CE3-CD2 3.24Å; W536-L548 HydrophobicContact CE3-CG 4.46Å; W536-L548 HydrophobicContact CG-CB 4.05Å; W536-L548 HydrophobicContact CG-CD2 3.87Å; W536-L548 HydrophobicContact CG-CG 4.46Å; W536-L548 HydrophobicContact CH2-CD2 4.12Å; W536-L548 HydrophobicContact CZ2-CB 3.93Å; W536-L548 HydrophobicContact CZ2-CD2 4.26Å; W536-L548 HydrophobicContact CZ3-CD2 3.62Å; W536-M556 HydrophobicContact CG-SD 4.34Å
537K95.1Very high87.8Confident139 Ų13954.1 Ų54.160%0.60433%0.333SS*.  trans-77.7135.2178.6-62.8-177.3179.4-178.80110.1T535 N546 M556T535-K537 PolarHBondContact O-N 2.95Å; K537-N546 PolarHBondContact O-ND2 2.05Å; K537-M556 HydrophobicContact CB-CE 4.2Å
538P95.9Very high87.7Confident42 Ų4254 Ų5427%0.27333%0.332SS..  trans-55.8159.4171-22.931.7000112.3T469 V470 Y471 T540 N546T469-P538 HydrophobicContact CG2-CB 4.05Å; T469-P538 HydrophobicContact CG2-CG 3.87Å; V470-P538 CarbonylContact O-C 3.51Å; V470-P538 WeakPolarHBondContact O-CA 3.24Å; Y471-P538 HydrophobicContact CD1-CG 4.45Å; Y471-P538 HydrophobicContact CE1-CB 4.31Å; Y471-P538 HydrophobicContact CE1-CG 3.68Å; P538-T540 PolarHBondContact O-N 2.98Å; P538-N546 PolarHBondContact O-ND2 2.93Å
539L92.7Very high87.7Confident5 Ų550.9 Ų50.93%0.02631%0.312CS..  trans-67.3113.2172.2-163.471.9000109.3A460 V461 R464 V470 L472 G544 N546A460-L539 HydrophobicContact CB-CD2 3.71Å; V461-L539 HydrophobicContact CG2-CD2 4.22Å; R464-L539 VanDerWaalsContact CD-O 3.27Å; R464-L539 WeakPolarHBondContact CD-O 3.14Å; R464-L539 WeakPolarHBondContact CG-O 3.48Å; V470-L539 HydrophobicContact CB-CB 4.09Å; V470-L539 HydrophobicContact CG1-CB 4.27Å; V470-L539 HydrophobicContact CG1-CD2 4.37Å; V470-L539 PolarHBondContact O-N 3.15Å; L472-L539 HydrophobicContact CB-CD1 4.37Å; L472-L539 HydrophobicContact CD2-CD1 4.14Å; L539-G544 WeakPolarHBondContact CD1-O 3.44Å; L539-N546 WeakPolarHBondContact CD1-O 3.32Å
540T78.4Confident87.7Confident78 Ų7844.9 Ų44.948%0.47928%0.281SS..  trans-123.2143.1-17653.10000112.1P538 D543 G544 N546P538-T540 PolarHBondContact O-N 2.98Å; T540-D543 CarbonylContact O-C 3.52Å; T540-G544 VanDerWaalsContact O-CA 3.26Å; T540-G544 WeakPolarHBondContact O-CA 2.99Å; T540-G544 PolarHBondContact O-N 3.34Å; T540-N546 PolarHBondContact N-OD1 3.4Å
541A70.1Confident87.6Confident58 Ų5843.7 Ų43.748%0.47927%0.271SS..SBendtrans-71.3155.1166.400000111
542P55.4Low87.4Confident84 Ų8445.8 Ų45.855%0.54528%0.283SS..SBendcis-83.9-13.2-634.3-34.3000113.2G544 S582P542-G544 PolarHBondContact O-N 3.46Å; P542-S582 WeakPolarHBondContact CB-O 3.49Å
543D57.8Low87.5Confident122 Ų12248.1 Ų48.165%0.65228%0.282SS*.SBendtrans-78.233.5-175.5-59.4-31.4000112.8T540 G545 N546T540-D543 CarbonylContact O-C 3.52Å; D543-G545 PolarHBondContact O-N 2.97Å; D543-N546 PolarHBondContact O-N 3.45Å
544G65.6Low87.6Confident1 Ų145.3 Ų45.31%0.0125%0.249CC..THydrogen-bonded Turntrans-59.213.4-160.100000118Y457 L539 T540 P542Y457-G544 VanDerWaalsContact CE2-O 3.23Å; Y457-G544 WeakPolarHBondContact CE2-O 3.44Å; Y457-G544 VanDerWaalsContact OH-C 3.28Å; Y457-G544 PolarHBondContact OH-O 2.9Å; L539-G544 WeakPolarHBondContact CD1-O 3.44Å; T540-G544 VanDerWaalsContact O-CA 3.26Å; T540-G544 WeakPolarHBondContact O-CA 2.99Å; T540-G544 PolarHBondContact O-N 3.34Å; P542-G544 PolarHBondContact O-N 3.46Å
545G80.6Confident87.6Confident4 Ų446.6 Ų46.64%0.04125%0.254CS..THydrogen-bonded Turntrans-99.95.9172.400000115.1D543 F559 Y560D543-G545 PolarHBondContact O-N 2.97Å; G545-F559 CarbonylContact O-C 3.48Å; G545-F559 WeakPolarHBondContact O-CA 3.31Å; G545-F559 PolarHBondContact O-N 3.27Å; G545-Y560 PolarHBondContact O-N 3.26Å
546N92.2Very high87.5Confident24 Ų2445.9 Ų45.913%0.12825%0.246CC..  trans-65.9138.5179.765.8-75.1000112.4K537 P538 L539 T540 D543 M556 K557K537-N546 PolarHBondContact O-ND2 2.05Å; P538-N546 PolarHBondContact O-ND2 2.93Å; L539-N546 WeakPolarHBondContact CD1-O 3.32Å; T540-N546 PolarHBondContact N-OD1 3.4Å; D543-N546 PolarHBondContact O-N 3.45Å; N546-M556 HydrophobicContact CB-CE 4.23Å; N546-K557 WeakPolarHBondContact CA-O 3.47Å
547Y94.8Very high87.2Confident24 Ų2448.4 Ų48.49%0.09426%0.257CS..EExtended strand (participates in β ladder)trans-147.8159.9177.871.1-78.6000111.5L472 M556 K557 Y560L472-Y547 CarbonylContact O-C 3.54Å; L472-Y547 VanDerWaalsContact O-CA 3.23Å; L472-Y547 WeakPolarHBondContact O-CA 3.34Å; L472-Y547 WeakPolarHBondContact O-CB 3.05Å; Y547-M556 WeakPolarHBondContact O-CA 3.31Å; Y547-K557 HydrophobicContact CD1-CB 4.09Å; Y547-K557 WeakPolarHBondContact CD1-O 3.36Å; Y547-K557 HydrophobicContact CE1-CB 3.5Å; Y547-K557 VanDerWaalsContact CE1-CB 3.5Å; Y547-K557 HydrophobicContact CE2-CB 4.19Å; Y547-K557 HydrophobicContact CE2-CD 4.47Å; Y547-K557 PolarHBondContact N-O 3.35Å; Y547-K557 PolarHBondContact O-N 3.01Å; Y547-K557 WeakPolarHBondContact OH-CD 3.34Å; Y547-Y560 VanDerWaalsContact CD1-CA 3.43Å; Y547-Y560 AromaticContact CD1-CD2 3.9Å; Y547-Y560 HydrophobicContact CD1-CD2 3.9Å; Y547-Y560 HydrophobicContact CD1-CG 4.3Å; Y547-Y560 AromaticContact CD2-CD2 3.91Å; Y547-Y560 HydrophobicContact CD2-CD2 3.91Å; Y547-Y560 HydrophobicContact CE1-CD2 4.43Å; Y547-Y560 HydrophobicContact CE2-CD2 4.45Å; Y547-Y560 AromaticContact CG-CD2 3.61Å; Y547-Y560 HydrophobicContact CG-CD2 3.61Å; Y547-Y560 HydrophobicContact CG-CG 4.37Å
548L97Very high86.9Confident1 Ų145.8 Ų45.81%0.00525%0.254CS..EExtended strand (participates in β ladder)trans-87.3121.2170.9-174.264.8000110.2L472 Y473 S474 L516 V534 W536 I550 L554 M556L472-L548 PolarHBondContact O-N 3.22Å; Y473-L548 CarbonylContact C-O 3.18Å; Y473-L548 WeakPolarHBondContact CA-O 3.33Å; Y473-L548 WeakPolarHBondContact CB-O 3.03Å; S474-L548 PolarHBondContact N-O 2.88Å; L516-L548 HydrophobicContact CD1-CD2 3.86Å; L516-L548 HydrophobicContact CD2-CD2 4.15Å; V534-L548 HydrophobicContact CG1-CD1 4.02Å; W536-L548 HydrophobicContact CB-CD2 4.31Å; W536-L548 HydrophobicContact CD2-CB 3.79Å; W536-L548 HydrophobicContact CD2-CD2 3.36Å; W536-L548 HydrophobicContact CD2-CG 4.19Å; W536-L548 VanDerWaalsContact CE2-CB 3.49Å; W536-L548 HydrophobicContact CE3-CB 4.43Å; W536-L548 HydrophobicContact CE3-CD2 3.24Å; W536-L548 HydrophobicContact CE3-CG 4.46Å; W536-L548 HydrophobicContact CG-CB 4.05Å; W536-L548 HydrophobicContact CG-CD2 3.87Å; W536-L548 HydrophobicContact CG-CG 4.46Å; W536-L548 HydrophobicContact CH2-CD2 4.12Å; W536-L548 HydrophobicContact CZ2-CB 3.93Å; W536-L548 HydrophobicContact CZ2-CD2 4.26Å; W536-L548 HydrophobicContact CZ3-CD2 3.62Å; L548-I550 HydrophobicContact CD2-CG1 4.28Å; L548-I550 HydrophobicContact CG-CG1 4.28Å; L548-L554 HydrophobicContact CD1-CD1 3.77Å; L548-L554 HydrophobicContact CD1-CG 3.87Å; L548-L554 HydrophobicContact CD2-CD1 3.87Å; L548-L554 HydrophobicContact CG-CD1 3.85Å; L548-L554 HydrophobicContact CG-CG 4.48Å; L548-M556 HydrophobicContact CB-SD 4.01Å; L548-M556 HydrophobicContact CD1-SD 3.9Å
549S96.5Very high86.4Confident0 Ų047.9 Ų47.90%026%0.26CS..EExtended strand (participates in β ladder)trans-86.5112.9170.4-178.50000108.5D476 E555 K557D476-S549 WeakPolarHBondContact OD2-CB 3.24Å; D476-S549 PolarHBondContact OD2-OG 3.38Å; S549-E555 WeakPolarHBondContact CB-O 3.49Å; S549-E555 PolarHBondContact N-O 3.1Å; S549-E555 PolarHBondContact O-N 2.85Å; S549-K557 PolarHBondContact OG-NZ 3.15Å
550I96.9Very high86.2Confident3 Ų347.8 Ų47.82%0.01526%0.259CS..EExtended strand (participates in β ladder)trans-94.198.8177.6-55.2176.1000108.2Y473 S474 F475 D476 Y477 L516 L548 L554Y473-I550 HydrophobicContact CD2-CD1 3.83Å; Y473-I550 HydrophobicContact CG-CD1 4.12Å; S474-I550 PolarHBondContact O-N 3.43Å; F475-I550 HydrophobicContact CD2-CB 4.06Å; F475-I550 HydrophobicContact CD2-CD1 4.4Å; F475-I550 HydrophobicContact CD2-CG2 3.85Å; F475-I550 HydrophobicContact CE2-CG2 3.84Å; D476-I550 PolarHBondContact N-O 3.11Å; Y477-I550 PolarHBondContact N-O 3.46Å; L516-I550 HydrophobicContact CD1-CD1 4.09Å; L516-I550 HydrophobicContact CD1-CG1 4.46Å; L548-I550 HydrophobicContact CD2-CG1 4.28Å; L548-I550 HydrophobicContact CG-CG1 4.28Å; I550-L554 HydrophobicContact CG1-CD1 4.16Å
551D94.9Very high86.4Confident47 Ų4745.6 Ų45.625%0.25124%0.243SC..SBendtrans-142.7-172.5177.2-158.3-8.5000109.3D476 R505 I509 K553D476-D551 HydrophobicContact CB-CB 4.19Å; R505-D551 IonicContact NH2-OD1 3.34Å; I509-D551 VanDerWaalsContact CD1-O 3.26Å; I509-D551 WeakPolarHBondContact CD1-O 3.43Å; D551-K553 CarbonylContact O-C 3.55Å; D551-K553 PolarHBondContact O-N 3.33Å; D551-K553 VanDerWaalsContact O-N 3.08Å
552D92Very high86.3Confident68 Ų6846.3 Ų46.336%0.36424%0.237SC..SBendtrans-47.5-38.9174.6-79.9-44.3000113.5R505 K508R505-D552 WeakPolarHBondContact CD-OD1 3.29Å; R505-D552 WeakPolarHBondContact CG-OD1 3.09Å; R505-D552 IonicContact CZ-OD1 3.69Å; R505-D552 IonicContact CZ-OD2 3.21Å; R505-D552 IonicContact NE-OD1 3.75Å; R505-D552 PolarHBondContact NE-OD1 3.29Å; R505-D552 IonicContact NE-OD2 3.89Å; R505-D552 PolarHBondContact NE-OD2 3.16Å; R505-D552 IonicContact NH2-OD1 2.8Å; R505-D552 IonicContact NH2-OD2 3.99Å; R505-D552 PolarHBondContact NH2-OD2 3.33Å; K508-D552 PolarHBondContact NZ-O 3.47Å
553K95Very high86.7Confident139 Ų13945.1 Ų45.160%0.60423%0.226SC*.SBendtrans-107.1104.1171.1-174.1-170.3176.4-148.30107.8D551 E555D551-K553 CarbonylContact O-C 3.55Å; D551-K553 PolarHBondContact O-N 3.33Å; D551-K553 VanDerWaalsContact O-N 3.08Å; K553-E555 WeakPolarHBondContact CE-OE2 3.24Å; K553-E555 IonicContact NZ-OE2 2.7Å; K553-E555 PolarHBondContact NZ-OE2 3.28Å; K553-E555 PolarHBondContact O-N 3.04Å
554L97.6Very high87Confident14 Ų1439.4 Ų39.47%0.07320%0.195CC..  trans-62.2127.2169.4-16664.7000108.8V512 I531 V534 L548 I550V512-L554 HydrophobicContact CG1-CD1 3.95Å; V512-L554 HydrophobicContact CG1-CD2 4.01Å; I531-L554 HydrophobicContact CB-CD2 4.27Å; I531-L554 HydrophobicContact CG2-CD2 4.06Å; V534-L554 HydrophobicContact CB-CD2 4.27Å; V534-L554 HydrophobicContact CB-CG 4.44Å; V534-L554 WeakPolarHBondContact CG2-O 3.36Å; L548-L554 HydrophobicContact CD1-CD1 3.77Å; L548-L554 HydrophobicContact CD1-CG 3.87Å; L548-L554 HydrophobicContact CD2-CD1 3.87Å; L548-L554 HydrophobicContact CG-CD1 3.85Å; L548-L554 HydrophobicContact CG-CG 4.48Å; I550-L554 HydrophobicContact CG1-CD1 4.16Å
555E96.3Very high87.4Confident51 Ų5139.3 Ų39.324%0.23820%0.195CC..EExtended strand (participates in β ladder)trans-156.6144.6178.761.1-172.3179.900113S549 K553 K557S549-E555 WeakPolarHBondContact CB-O 3.49Å; S549-E555 PolarHBondContact N-O 3.1Å; S549-E555 PolarHBondContact O-N 2.85Å; K553-E555 WeakPolarHBondContact CE-OE2 3.24Å; K553-E555 IonicContact NZ-OE2 2.7Å; K553-E555 PolarHBondContact NZ-OE2 3.28Å; K553-E555 PolarHBondContact O-N 3.04Å; E555-K557 HydrophobicContact CG-CG 4.23Å; E555-K557 WeakPolarHBondContact OE1-CE 3.34Å; E555-K557 IonicContact OE1-NZ 2.71Å; E555-K557 PolarHBondContact OE1-NZ 2.96Å
556M94.9Very high87Confident54 Ų5440.2 Ų40.227%0.26620%0.2SC..EExtended strand (participates in β ladder)trans-75128.1167.5-70.9-60.2-57.200109.1V534 W536 K537 N546 Y547 L548V534-M556 HydrophobicContact CG1-CG 4.28Å; W536-M556 HydrophobicContact CG-SD 4.34Å; K537-M556 HydrophobicContact CB-CE 4.2Å; N546-M556 HydrophobicContact CB-CE 4.23Å; Y547-M556 WeakPolarHBondContact O-CA 3.31Å; L548-M556 HydrophobicContact CB-SD 4.01Å; L548-M556 HydrophobicContact CD1-SD 3.9Å
557K92.7Very high86.4Confident59 Ų5940.3 Ų40.326%0.25720%0.199SC..EExtended strand (participates in β ladder)trans-115.6144.6175-73.8-174.1175.6143.30110.8N546 Y547 S549 E555N546-K557 WeakPolarHBondContact CA-O 3.47Å; Y547-K557 HydrophobicContact CD1-CB 4.09Å; Y547-K557 WeakPolarHBondContact CD1-O 3.36Å; Y547-K557 HydrophobicContact CE1-CB 3.5Å; Y547-K557 VanDerWaalsContact CE1-CB 3.5Å; Y547-K557 HydrophobicContact CE2-CB 4.19Å; Y547-K557 HydrophobicContact CE2-CD 4.47Å; Y547-K557 PolarHBondContact N-O 3.35Å; Y547-K557 PolarHBondContact O-N 3.01Å; Y547-K557 WeakPolarHBondContact OH-CD 3.34Å; S549-K557 PolarHBondContact OG-NZ 3.15Å; E555-K557 HydrophobicContact CG-CG 4.23Å; E555-K557 WeakPolarHBondContact OE1-CE 3.34Å; E555-K557 IonicContact OE1-NZ 2.71Å; E555-K557 PolarHBondContact OE1-NZ 2.96Å
558P88.7Confident85.6Confident83 Ų8339.1 Ų39.154%0.53920%0.195SC..SBendtrans-77.9163.4167.436.2-35.5000110.3
559F84.9Confident84.4Confident87 Ų8739.9 Ų39.938%0.38220%0.2SC..SBendtrans54.871169.1-42.1-64.3000115.6G545 H561 E562G545-F559 CarbonylContact O-C 3.48Å; G545-F559 WeakPolarHBondContact O-CA 3.31Å; G545-F559 PolarHBondContact O-N 3.27Å; F559-H561 PolarHBondContact O-N 3.1Å; F559-E562 HydrophobicContact CB-CB 3.62Å; F559-E562 HydrophobicContact CB-CG 3.7Å; F559-E562 HydrophobicContact CG-CG 4.16Å; F559-E562 PolarHBondContact O-N 3.2Å; F559-E562 VanDerWaalsContact O-N 3.11Å
560Y88.3Confident83.1Confident2 Ų246.2 Ų46.21%0.00823%0.234CC..THydrogen-bonded Turntrans-48.9110.7171.4-177-106.6000111.1T369 Y457 L472 G545 Y547 E562 M565T369-Y560 WeakPolarHBondContact CB-OH 3.23Å; T369-Y560 WeakPolarHBondContact CG2-OH 3.39Å; T369-Y560 PolarHBondContact OG1-OH 3.1Å; Y457-Y560 AromaticContact CD2-CD1 3.78Å; Y457-Y560 HydrophobicContact CD2-CD1 3.78Å; Y457-Y560 HydrophobicContact CD2-CG 4.44Å; Y457-Y560 HydrophobicContact CG-CD1 4.16Å; L472-Y560 HydrophobicContact CD1-CD2 4.46Å; L472-Y560 HydrophobicContact CD1-CE1 4.31Å; L472-Y560 HydrophobicContact CD1-CE2 4.13Å; L472-Y560 HydrophobicContact CD2-CD1 3.83Å; L472-Y560 HydrophobicContact CD2-CD2 3.87Å; L472-Y560 HydrophobicContact CD2-CE1 4.28Å; L472-Y560 HydrophobicContact CD2-CE2 4.34Å; L472-Y560 HydrophobicContact CD2-CG 3.59Å; L472-Y560 HydrophobicContact CG-CD2 4.04Å; L472-Y560 HydrophobicContact CG-CE2 4.16Å; L472-Y560 HydrophobicContact CG-CG 4.26Å; G545-Y560 PolarHBondContact O-N 3.26Å; Y547-Y560 VanDerWaalsContact CD1-CA 3.43Å; Y547-Y560 AromaticContact CD1-CD2 3.9Å; Y547-Y560 HydrophobicContact CD1-CD2 3.9Å; Y547-Y560 HydrophobicContact CD1-CG 4.3Å; Y547-Y560 AromaticContact CD2-CD2 3.91Å; Y547-Y560 HydrophobicContact CD2-CD2 3.91Å; Y547-Y560 HydrophobicContact CE1-CD2 4.43Å; Y547-Y560 HydrophobicContact CE2-CD2 4.45Å; Y547-Y560 AromaticContact CG-CD2 3.61Å; Y547-Y560 HydrophobicContact CG-CD2 3.61Å; Y547-Y560 HydrophobicContact CG-CG 4.37Å; Y560-E562 PolarHBondContact O-N 3.4Å; Y560-E562 VanDerWaalsContact O-N 3.11Å; Y560-M565 HydrophobicContact CD1-CG 4.41Å; Y560-M565 WeakPolarHBondContact O-CG 3.48Å
561H82.8Confident81.5Confident33 Ų3346.9 Ų46.915%0.15324%0.237CC..THydrogen-bonded Turntrans45.241.2-176.5-56.6-64.1000114.4F453 F559 N563 G564 M565F453-H561 HydrophobicContact CB-CB 4.46Å; F453-H561 AromaticContact CD1-CD2 3.8Å; F453-H561 AromaticContact CD1-NE2 3.6Å; F453-H561 HydrophobicContact CD2-CB 4.02Å; F453-H561 AromaticContact CD2-CD2 3.56Å; F453-H561 AromaticContact CD2-CE1 3.84Å; F453-H561 AromaticContact CD2-CG 3.48Å; F453-H561 VanDerWaalsContact CD2-CG 3.48Å; F453-H561 AromaticContact CD2-ND1 3.68Å; F453-H561 AromaticContact CD2-NE2 3.78Å; F453-H561 AromaticContact CE1-CE1 3.91Å; F453-H561 AromaticContact CE1-NE2 3.61Å; F453-H561 AromaticContact CE2-CE1 3.47Å; F453-H561 VanDerWaalsContact CE2-CE1 3.47Å; F453-H561 WeakPolarHBondContact CE2-CE1 3.28Å; F453-H561 AromaticContact CE2-CG 3.84Å; F453-H561 AromaticContact CE2-ND1 3.51Å; F453-H561 AromaticContact CE2-NE2 3.78Å; F453-H561 HydrophobicContact CG-CB 4.49Å; F453-H561 AromaticContact CG-CD2 3.44Å; F453-H561 VanDerWaalsContact CG-CD2 3.44Å; F453-H561 WeakPolarHBondContact CG-CD2 3.11Å; F453-H561 AromaticContact CG-CG 3.86Å; F453-H561 AromaticContact CG-NE2 3.7Å; F453-H561 AromaticContact CZ-CE1 3.52Å; F453-H561 AromaticContact CZ-NE2 3.71Å; F559-H561 PolarHBondContact O-N 3.1Å; H561-N563 PolarHBondContact O-N 2.85Å; H561-G564 PolarHBondContact O-N 2.74Å; H561-M565 HydrophobicContact CB-CE 4.06Å; H561-M565 HydrophobicContact CB-CG 4.41Å
562E66.6Low80Confident73 Ų7346.4 Ų46.434%0.34123%0.233SC..Hα-helixtrans-22.3-59.8-170.3-169173.2-178.100117.1F559 Y560 G564 M565F559-E562 HydrophobicContact CB-CB 3.62Å; F559-E562 HydrophobicContact CB-CG 3.7Å; F559-E562 HydrophobicContact CG-CG 4.16Å; F559-E562 PolarHBondContact O-N 3.2Å; F559-E562 VanDerWaalsContact O-N 3.11Å; Y560-E562 PolarHBondContact O-N 3.4Å; Y560-E562 VanDerWaalsContact O-N 3.11Å; E562-G564 VanDerWaalsContact C-N 3.29Å; E562-G564 PolarHBondContact O-N 2.94Å; E562-M565 PolarHBondContact O-N 3.32Å
563N64.6Low78.2Confident59 Ų5948.1 Ų48.132%0.31624%0.242SC..Hα-helixtrans-67.4-28.3-172.3-66.3-20.9000113H561H561-N563 PolarHBondContact O-N 2.85Å
564G64Low76.1Confident1 Ų142 Ų421%0.0122%0.217CC..Hα-helixtrans-76.5-43.7176.700000111.8D449 H561 E562 S566 F567 W568D449-G564 WeakPolarHBondContact OD2-CA 3.29Å; H561-G564 PolarHBondContact O-N 2.74Å; E562-G564 VanDerWaalsContact C-N 3.29Å; E562-G564 PolarHBondContact O-N 2.94Å; G564-S566 VanDerWaalsContact C-N 3.31Å; G564-S566 PolarHBondContact O-N 2.96Å; G564-F567 PolarHBondContact O-N 3.27Å; G564-W568 PolarHBondContact O-N 3.42Å
565M74.4Confident73.8Confident0 Ų043.9 Ų43.90%023%0.232CC..Hα-helixtrans-74.9-19.4-166.3-57.3-51.4108.800113.8F453 W454 Y457 Y560 H561 E562 P569 F584F453-M565 HydrophobicContact CB-CE 3.54Å; F453-M565 HydrophobicContact CB-SD 4.49Å; W454-M565 VanDerWaalsContact CA-SD 3.5Å; W454-M565 HydrophobicContact CB-CE 4.01Å; W454-M565 HydrophobicContact CB-SD 4.11Å; W454-M565 HydrophobicContact CE3-SD 3.92Å; Y457-M565 VanDerWaalsContact CB-SD 3.58Å; Y457-M565 HydrophobicContact CD1-CB 3.89Å; Y457-M565 HydrophobicContact CD1-CG 3.97Å; Y457-M565 HydrophobicContact CD1-SD 3.97Å; Y457-M565 HydrophobicContact CE1-CB 4.01Å; Y457-M565 HydrophobicContact CE1-CG 4.46Å; Y457-M565 HydrophobicContact CG-CB 4.45Å; Y457-M565 HydrophobicContact CG-CG 4.04Å; Y457-M565 HydrophobicContact CG-SD 3.91Å; Y560-M565 HydrophobicContact CD1-CG 4.41Å; Y560-M565 WeakPolarHBondContact O-CG 3.48Å; H561-M565 HydrophobicContact CB-CE 4.06Å; H561-M565 HydrophobicContact CB-CG 4.41Å; E562-M565 PolarHBondContact O-N 3.32Å; M565-P569 WeakPolarHBondContact O-CD 3.45Å; M565-P569 WeakPolarHBondContact O-CG 3.22Å; M565-F584 HydrophobicContact CB-CE2 3.9Å; M565-F584 HydrophobicContact CB-CZ 3.91Å
566S71.6Confident71.6Confident23 Ų2347.2 Ų47.216%0.16125%0.247CC..THydrogen-bonded Turntrans-85.4-26.3172.5590000113.9G564 N570G564-S566 VanDerWaalsContact C-N 3.31Å; G564-S566 PolarHBondContact O-N 2.96Å; S566-N570 PolarHBondContact O-ND2 3Å
567F79.7Confident69.5Low25 Ų2545.9 Ų45.911%0.1124%0.241CC..Hα-helixtrans-79.2-49.8-175.5170.5-103.7000112.1D418 C419 E422 Y423 G564 N570 L571D418-F567 HydrophobicContact CB-CE2 4.43Å; C419-F567 HydrophobicContact CB-CE1 4.4Å; C419-F567 HydrophobicContact CB-CZ 4.03Å; E422-F567 HydrophobicContact CB-CD2 4.06Å; E422-F567 HydrophobicContact CB-CE2 3.99Å; E422-F567 HydrophobicContact CB-CZ 4.35Å; E422-F567 HydrophobicContact CG-CB 4.33Å; E422-F567 HydrophobicContact CG-CD1 4.31Å; E422-F567 HydrophobicContact CG-CD2 3.85Å; E422-F567 HydrophobicContact CG-CE2 4.26Å; E422-F567 HydrophobicContact CG-CG 3.89Å; Y423-F567 HydrophobicContact CE2-CE1 4.37Å; G564-F567 PolarHBondContact O-N 3.27Å; F567-N570 PolarHBondContact O-N 2.83Å; F567-L571 HydrophobicContact CE1-CD2 3.64Å; F567-L571 HydrophobicContact CE2-CD1 4.49Å; F567-L571 HydrophobicContact CZ-CB 4.42Å; F567-L571 HydrophobicContact CZ-CD1 4.07Å; F567-L571 HydrophobicContact CZ-CD2 3.63Å; F567-L571 HydrophobicContact CZ-CG 4.28Å; F567-L571 PolarHBondContact O-N 2.95Å; F567-L571 VanDerWaalsContact O-N 3.14Å
568W78.7Confident67.4Low0 Ų043.8 Ų43.80%023%0.232CC..Hα-helixtrans-61.2-43.3-175.3-68.6116.7000115.6V401 L402 Y423 L446 N450 W454 G564 N570 L571 F572V401-W568 HydrophobicContact CG1-CH2 3.58Å; V401-W568 HydrophobicContact CG1-CZ3 3.82Å; L402-W568 HydrophobicContact CD2-CZ3 4.19Å; Y423-W568 AromaticContact CE2-CZ2 3.97Å; Y423-W568 HydrophobicContact CE2-CZ2 3.97Å; Y423-W568 VanDerWaalsContact OH-CZ2 3.28Å; Y423-W568 WeakPolarHBondContact OH-CZ2 3.5Å; Y423-W568 PolarHBondContact OH-NE1 2.75Å; L446-W568 HydrophobicContact CD1-CH2 3.68Å; L446-W568 HydrophobicContact CD1-CZ2 3.59Å; N450-W568 HydrophobicContact CB-CH2 3.98Å; N450-W568 HydrophobicContact CB-CZ2 3.69Å; W454-W568 HydrophobicContact CB-CB 4.38Å; W454-W568 HydrophobicContact CB-CG 4.17Å; W454-W568 HydrophobicContact CD2-CB 3.54Å; W454-W568 HydrophobicContact CD2-CG 4.25Å; W454-W568 HydrophobicContact CE3-CB 4.01Å; W454-W568 HydrophobicContact CG-CB 3.69Å; W454-W568 AromaticContact CG-CD1 3.98Å; W454-W568 AromaticContact CG-CG 3.92Å; W454-W568 HydrophobicContact CG-CG 3.92Å; W454-W568 HydrophobicContact CH2-CB 4.49Å; W454-W568 HydrophobicContact CZ2-CB 4.17Å; W454-W568 HydrophobicContact CZ3-CB 4.47Å; G564-W568 PolarHBondContact O-N 3.42Å; W568-N570 VanDerWaalsContact C-N 3.27Å; W568-N570 PolarHBondContact O-N 3.42Å; W568-L571 HydrophobicContact CE3-CD2 3.77Å; W568-L571 HydrophobicContact CZ3-CD2 3.61Å; W568-L571 PolarHBondContact O-N 3.38Å; W568-L571 VanDerWaalsContact O-N 3.13Å; W568-F572 HydrophobicContact CB-CD2 3.98Å; W568-F572 HydrophobicContact CB-CE2 3.76Å; W568-F572 AromaticContact CD2-CE2 3.84Å; W568-F572 HydrophobicContact CD2-CE2 3.84Å; W568-F572 HydrophobicContact CD2-CZ 4.27Å; W568-F572 HydrophobicContact CE3-CD2 4.21Å; W568-F572 HydrophobicContact CE3-CE1 4.35Å; W568-F572 AromaticContact CE3-CE2 3.25Å; W568-F572 HydrophobicContact CE3-CE2 3.25Å; W568-F572 AromaticContact CE3-CZ 3.33Å; W568-F572 HydrophobicContact CE3-CZ 3.33Å; W568-F572 HydrophobicContact CG-CE2 4.08Å; W568-F572 HydrophobicContact CZ3-CE2 4.12Å; W568-F572 AromaticContact CZ3-CZ 3.71Å; W568-F572 HydrophobicContact CZ3-CZ 3.71Å; W568-F572 WeakPolarHBondContact O-CD2 3.43Å; W568-F572 WeakPolarHBondContact O-CG 3.28Å; W568-F572 PolarHBondContact O-N 2.83Å
569P70.9Confident65.5Low16 Ų1645.4 Ų45.410%0.10424%0.236CC..Hα-helixtrans-58.6-41.9178.4-0.8-1000112.3W454 M565 L571 F572 D573 A574 F578W454-P569 HydrophobicContact CH2-CB 3.53Å; W454-P569 HydrophobicContact CH2-CG 3.29Å; W454-P569 HydrophobicContact CZ2-CB 4.22Å; W454-P569 HydrophobicContact CZ2-CG 4.27Å; W454-P569 HydrophobicContact CZ3-CB 4.31Å; W454-P569 VanDerWaalsContact CZ3-CD 3.43Å; W454-P569 HydrophobicContact CZ3-CG 3.56Å; M565-P569 WeakPolarHBondContact O-CD 3.45Å; M565-P569 WeakPolarHBondContact O-CG 3.22Å; P569-L571 VanDerWaalsContact C-N 3.34Å; P569-L571 PolarHBondContact O-N 2.77Å; P569-F572 PolarHBondContact O-N 3.19Å; P569-D573 PolarHBondContact O-N 3.44Å; P569-A574 HydrophobicContact CB-CB 4.23Å; P569-A574 PolarHBondContact O-N 3.31Å; P569-F578 HydrophobicContact CB-CD2 3.87Å; P569-F578 HydrophobicContact CB-CE2 4.09Å; P569-F578 HydrophobicContact CB-CG 4.45Å; P569-F578 HydrophobicContact CG-CE2 4.48Å
570N68.8Low63.5Low134 Ų13450.2 Ų50.272%0.71726%0.257SS*.Hα-helixtrans-65.9-37.2178.4-72.1-46000112S566 F567 W568S566-N570 PolarHBondContact O-ND2 3Å; F567-N570 PolarHBondContact O-N 2.83Å; W568-N570 VanDerWaalsContact C-N 3.27Å; W568-N570 PolarHBondContact O-N 3.42Å
571L65.2Low61.4Low17 Ų1759.4 Ų59.49%0.08930%0.3CS..Hα-helixtrans-72.7-36.1-179.7-164.670.4000113.1L402 N415 F567 W568 P569 D573L402-L571 HydrophobicContact CD2-CD2 3.28Å; L402-L571 HydrophobicContact CD2-CG 4.12Å; N415-L571 HydrophobicContact CB-CD1 3.66Å; N415-L571 HydrophobicContact CB-CG 4.34Å; N415-L571 PolarHBondContact ND2-O 3.48Å; F567-L571 HydrophobicContact CE1-CD2 3.64Å; F567-L571 HydrophobicContact CE2-CD1 4.49Å; F567-L571 HydrophobicContact CZ-CB 4.42Å; F567-L571 HydrophobicContact CZ-CD1 4.07Å; F567-L571 HydrophobicContact CZ-CD2 3.63Å; F567-L571 HydrophobicContact CZ-CG 4.28Å; F567-L571 PolarHBondContact O-N 2.95Å; F567-L571 VanDerWaalsContact O-N 3.14Å; W568-L571 HydrophobicContact CE3-CD2 3.77Å; W568-L571 HydrophobicContact CZ3-CD2 3.61Å; W568-L571 PolarHBondContact O-N 3.38Å; W568-L571 VanDerWaalsContact O-N 3.13Å; P569-L571 VanDerWaalsContact C-N 3.34Å; P569-L571 PolarHBondContact O-N 2.77Å; L571-D573 VanDerWaalsContact C-N 3.31Å
572F61.4Low59.6Low37 Ų3760 Ų6016%0.16231%0.307CS..THydrogen-bonded Turntrans-84.7-2.5-178.2-66.6-55.5000113.7W405 I407 W454 W568 P569 A574W405-F572 HydrophobicContact CB-CD1 4.11Å; W405-F572 HydrophobicContact CB-CE1 3.46Å; W405-F572 VanDerWaalsContact CB-CE1 3.46Å; W405-F572 HydrophobicContact CB-CZ 4.3Å; W405-F572 AromaticContact CD1-CE1 3.71Å; W405-F572 AromaticContact CD1-CZ 3.66Å; W405-F572 HydrophobicContact CD2-CD1 4.16Å; W405-F572 AromaticContact CD2-CE1 3.5Å; W405-F572 HydrophobicContact CD2-CE1 3.5Å; W405-F572 VanDerWaalsContact CD2-CE1 3.5Å; W405-F572 HydrophobicContact CD2-CE2 4.29Å; W405-F572 AromaticContact CD2-CZ 3.59Å; W405-F572 HydrophobicContact CD2-CZ 3.59Å; W405-F572 AromaticContact CE2-CZ 3.69Å; W405-F572 HydrophobicContact CE3-CD1 4.19Å; W405-F572 AromaticContact CE3-CE1 3.99Å; W405-F572 HydrophobicContact CE3-CE1 3.99Å; W405-F572 HydrophobicContact CE3-CZ 4.23Å; W405-F572 HydrophobicContact CG-CD1 4.14Å; W405-F572 AromaticContact CG-CE1 3.24Å; W405-F572 HydrophobicContact CG-CE1 3.24Å; W405-F572 AromaticContact CG-CZ 3.59Å; W405-F572 HydrophobicContact CG-CZ 3.59Å; W405-F572 HydrophobicContact CZ2-CZ 4.39Å; W405-F572 AromaticContact NE1-CZ 3.75Å; I407-F572 HydrophobicContact CD1-CD1 3.7Å; I407-F572 HydrophobicContact CD1-CE1 3.66Å; I407-F572 HydrophobicContact CG1-CD1 4Å; I407-F572 HydrophobicContact CG1-CE1 4.13Å; W454-F572 AromaticContact CD1-CE2 3.81Å; W454-F572 HydrophobicContact CZ2-CD2 4.38Å; W454-F572 AromaticContact NE1-CD2 3.6Å; W454-F572 AromaticContact NE1-CE2 3.49Å; W568-F572 HydrophobicContact CB-CD2 3.98Å; W568-F572 HydrophobicContact CB-CE2 3.76Å; W568-F572 AromaticContact CD2-CE2 3.84Å; W568-F572 HydrophobicContact CD2-CE2 3.84Å; W568-F572 HydrophobicContact CD2-CZ 4.27Å; W568-F572 HydrophobicContact CE3-CD2 4.21Å; W568-F572 HydrophobicContact CE3-CE1 4.35Å; W568-F572 AromaticContact CE3-CE2 3.25Å; W568-F572 HydrophobicContact CE3-CE2 3.25Å; W568-F572 AromaticContact CE3-CZ 3.33Å; W568-F572 HydrophobicContact CE3-CZ 3.33Å; W568-F572 HydrophobicContact CG-CE2 4.08Å; W568-F572 HydrophobicContact CZ3-CE2 4.12Å; W568-F572 AromaticContact CZ3-CZ 3.71Å; W568-F572 HydrophobicContact CZ3-CZ 3.71Å; W568-F572 WeakPolarHBondContact O-CD2 3.43Å; W568-F572 WeakPolarHBondContact O-CG 3.28Å; W568-F572 PolarHBondContact O-N 2.83Å; P569-F572 PolarHBondContact O-N 3.19Å; F572-A574 HydrophobicContact CB-CB 4.16Å; F572-A574 PolarHBondContact O-N 3.19Å
573D54.6Low58.6Low104 Ų10457 Ų5756%0.55629%0.294SS*.THydrogen-bonded Turntrans47.642.9-164.7-165.424.5000109.6P569 L571 S575P569-D573 PolarHBondContact O-N 3.44Å; L571-D573 VanDerWaalsContact C-N 3.31Å; D573-S575 PolarHBondContact O-N 3.44Å
574A51.5Low57.4Low9 Ų957.3 Ų57.37%0.07429%0.293CS..G310 helixtrans-71.627.7-17800000111.4W454 P569 F572 Q576 I577 F578W454-A574 HydrophobicContact CZ2-CB 4.42Å; P569-A574 HydrophobicContact CB-CB 4.23Å; P569-A574 PolarHBondContact O-N 3.31Å; F572-A574 HydrophobicContact CB-CB 4.16Å; F572-A574 PolarHBondContact O-N 3.19Å; A574-Q576 PolarHBondContact O-N 3.29Å; A574-I577 HydrophobicContact CB-CB 4.28Å; A574-I577 HydrophobicContact CB-CD1 4.21Å; A574-I577 HydrophobicContact CB-CG1 4.37Å; A574-I577 WeakPolarHBondContact O-CA 3.22Å; A574-I577 WeakPolarHBondContact O-CB 3.46Å; A574-I577 PolarHBondContact O-N 2.98Å; A574-F578 HydrophobicContact CB-CD2 4.06Å; A574-F578 HydrophobicContact CB-CE2 4.35Å; A574-F578 PolarHBondContact O-N 3.38Å
575S50.2Low56Low55 Ų5567 Ų6739%0.38533%0.334SS..G310 helixtrans-61.1-11.5171.972.70000112.6D573D573-S575 PolarHBondContact O-N 3.44Å
576Q48.7Very low54Low120 Ų12074.8 Ų74.856%0.56136%0.364SS*.G310 helixtrans-79.5-20.5168.9-63.6-171.113.100113.2A574A574-Q576 PolarHBondContact O-N 3.29Å
577I50.4Low52.3Low26 Ų2681.2 Ų81.213%0.13339%0.389CS..THydrogen-bonded Turntrans-101-38-178.9-56.9-179.5000110.3I354 T462 A574I354-I577 HydrophobicContact CG2-CD1 4.35Å; I354-I577 HydrophobicContact CG2-CG1 4.43Å; T462-I577 HydrophobicContact CG2-CG2 3.61Å; A574-I577 HydrophobicContact CB-CB 4.28Å; A574-I577 HydrophobicContact CB-CD1 4.21Å; A574-I577 HydrophobicContact CB-CG1 4.37Å; A574-I577 WeakPolarHBondContact O-CA 3.22Å; A574-I577 WeakPolarHBondContact O-CB 3.46Å; A574-I577 PolarHBondContact O-N 2.98Å
578F50Low50Low16 Ų1684 Ų847%0.0741%0.408CS..SBendtrans-112.9129.5-177.8-61-91.6000110.8W454 Y457 A458 V461 P569 A574 K580 D583W454-F578 HydrophobicContact CH2-CD2 4.08Å; W454-F578 HydrophobicContact CH2-CE1 4.38Å; W454-F578 AromaticContact CH2-CE2 3.07Å; W454-F578 HydrophobicContact CH2-CE2 3.07Å; W454-F578 AromaticContact CH2-CZ 3.24Å; W454-F578 HydrophobicContact CH2-CZ 3.24Å; W454-F578 AromaticContact CZ2-CE2 3.77Å; W454-F578 HydrophobicContact CZ2-CE2 3.77Å; W454-F578 HydrophobicContact CZ2-CZ 4.23Å; W454-F578 HydrophobicContact CZ3-CE1 4.49Å; W454-F578 AromaticContact CZ3-CE2 3.9Å; W454-F578 HydrophobicContact CZ3-CE2 3.9Å; W454-F578 AromaticContact CZ3-CZ 3.55Å; W454-F578 HydrophobicContact CZ3-CZ 3.55Å; Y457-F578 HydrophobicContact CE1-CE1 4.13Å; Y457-F578 HydrophobicContact CE1-CZ 4.47Å; A458-F578 HydrophobicContact CB-CZ 4.37Å; V461-F578 HydrophobicContact CB-CE1 4.1Å; V461-F578 HydrophobicContact CG1-CD1 4.03Å; V461-F578 HydrophobicContact CG1-CE1 3.78Å; V461-F578 HydrophobicContact CG1-CZ 4.46Å; V461-F578 HydrophobicContact CG2-CE1 4.01Å; P569-F578 HydrophobicContact CB-CD2 3.87Å; P569-F578 HydrophobicContact CB-CE2 4.09Å; P569-F578 HydrophobicContact CB-CG 4.45Å; P569-F578 HydrophobicContact CG-CE2 4.48Å; A574-F578 HydrophobicContact CB-CD2 4.06Å; A574-F578 HydrophobicContact CB-CE2 4.35Å; A574-F578 PolarHBondContact O-N 3.38Å; F578-K580 PolarHBondContact O-N 3Å; F578-D583 HydrophobicContact CD1-CB 3.91Å
579D48.5Very low47.8Very low117 Ų11789.5 Ų89.563%0.62643%0.432SS*.  trans-63.9128.6164.9-85.7-33.5000109.1E581 S582D579-E581 PolarHBondContact O-N 2.72Å; D579-S582 PolarHBondContact O-N 3.1Å
580K42.5Very low45.8Very low187 Ų18795.6 Ų95.681%0.81346%0.458SS*.THydrogen-bonded Turntrans-56-21.8-170.4-78.7-175.4175.91780115.1F578F578-K580 PolarHBondContact O-N 3Å
581E44.1Very low44Very low196 Ų19695.4 Ų95.492%0.91646%0.457SS*.THydrogen-bonded Turntrans-107.5-17-169.9-76.2-171.1153.100115.4D579D579-E581 PolarHBondContact O-N 2.72Å
582S44.5Very low42.3Very low44 Ų4499.3 Ų99.331%0.30848%0.482SS..THydrogen-bonded Turntrans-107.5-26.8-164.956.60000116.3P542 D579P542-S582 WeakPolarHBondContact CB-O 3.49Å; D579-S582 PolarHBondContact O-N 3.1Å
583D45.7Very low40.7Very low11 Ų11100.1 Ų100.16%0.05950%0.495CS..SBendtrans-104.2-7-161.4-81-31.3000117.1R464 F578R464-D583 IonicContact CZ-OD1 3.38Å; R464-D583 IonicContact CZ-OD2 3.9Å; R464-D583 IonicContact NH1-OD1 2.65Å; R464-D583 PolarHBondContact NH1-OD1 2.86Å; R464-D583 VanDerWaalsContact NH2-CG 3.3Å; R464-D583 IonicContact NH2-OD1 2.92Å; R464-D583 PolarHBondContact NH2-OD1 2.82Å; R464-D583 IonicContact NH2-OD2 2.86Å; R464-D583 PolarHBondContact NH2-OD2 2.99Å; F578-D583 HydrophobicContact CD1-CB 3.91Å
584F40.9Very low39.6Very low66 Ų6699.9 Ų99.929%0.28950%0.502SS..  trans-156.292.2172.7-109.3-82.2000111.9Y457 M565 R586Y457-F584 HydrophobicContact CE1-CE2 4.13Å; M565-F584 HydrophobicContact CB-CE2 3.9Å; M565-F584 HydrophobicContact CB-CZ 3.91Å; F584-R586 VanDerWaalsContact C-N 3.31Å; F584-R586 PolarHBondContact O-N 3.31Å
585K33.6Very low38.7Very low203 Ų203104.9 Ų104.988%0.88354%0.536SS*.  trans-70.299.6150.2-79.7-174.4179.9176.90106.1K587K585-K587 PolarHBondContact O-N 3.5Å
586R33.2Very low37.9Very low165 Ų165105.6 Ų105.662%0.62354%0.541SS*.  trans-45.1118.5160.9-166.4175.3-166.5168.84.6105.1F584 V588F584-R586 VanDerWaalsContact C-N 3.31Å; F584-R586 PolarHBondContact O-N 3.31Å; R586-V588 HydrophobicContact CB-CG2 4.27Å; R586-V588 HydrophobicContact CG-CG2 4.49Å; R586-V588 PolarHBondContact O-N 3.5Å
587K34.3Very low37.2Very low157 Ų157106.7 Ų106.768%0.68356%0.557SS**  trans-65.189.4158.5-155176.4-172.4179.60103.3K585 F589K585-K587 PolarHBondContact O-N 3.5Å; K587-F589 PolarHBondContact O-N 3.35Å; K587-F589 VanDerWaalsContact O-N 3.11Å
588V32.5Very low36.8Very low84 Ų84112.2 Ų112.251%0.50959%0.587SS.*  trans-53.9123-178.7173.70000104.5R586 H590R586-V588 HydrophobicContact CB-CG2 4.27Å; R586-V588 HydrophobicContact CG-CG2 4.49Å; R586-V588 PolarHBondContact O-N 3.5Å; V588-H590 HydrophobicContact CG1-CB 4.32Å; V588-H590 VanDerWaalsContact CG1-CD2 3.48Å; V588-H590 WeakPolarHBondContact CG1-CD2 3.42Å; V588-H590 PolarHBondContact O-N 2.89Å
589F32.1Very low36.3Very low116 Ų116117.1 Ų117.151%0.50961%0.611SS.*THydrogen-bonded Turntrans-65.428.2-172.7-112.4-92.2000113.7K587K587-F589 PolarHBondContact O-N 3.35Å; K587-F589 VanDerWaalsContact O-N 3.11Å
590H29.9Very low36.4Very low143 Ų143114.5 Ų114.566%0.66260%0.6SS**THydrogen-bonded Turntrans-93.7-18.3176.1-76-52000113.9V588 A593V588-H590 HydrophobicContact CG1-CB 4.32Å; V588-H590 VanDerWaalsContact CG1-CD2 3.48Å; V588-H590 WeakPolarHBondContact CG1-CD2 3.42Å; V588-H590 PolarHBondContact O-N 2.89Å; H590-A593 WeakPolarHBondContact O-CB 3.47Å; H590-A593 PolarHBondContact O-N 3.43Å
591D30.4Very low37Very low130 Ų130108.6 Ų108.670%0.69558%0.583SS**SBendtrans-83.1-24.5-177.6-72.7-8.8000113.9S594D591-S594 PolarHBondContact O-OG 3.46Å
592T29.3Very low37.8Very low100 Ų100105.7 Ų105.761%0.61357%0.569SS**G310 helixtrans-87.7-3.5168.642.50000113.5S594T592-S594 PolarHBondContact O-N 3.43Å; T592-S594 VanDerWaalsContact O-N 3.11Å
593A28.1Very low39.2Very low53 Ų53107.6 Ų107.644%0.43858%0.579SS.*G310 helixtrans-72.14.9169.200000112.9H590 S595H590-A593 WeakPolarHBondContact O-CB 3.47Å; H590-A593 PolarHBondContact O-N 3.43Å; A593-S595 PolarHBondContact O-N 2.88Å
594S30.9Very low40.6Very low100 Ų100110.4 Ų110.470%0.69959%0.594SS**G310 helixtrans-84.44.1-172.358.50000116.3D591 T592D591-S594 PolarHBondContact O-OG 3.46Å; T592-S594 PolarHBondContact O-N 3.43Å; T592-S594 VanDerWaalsContact O-N 3.11Å
595S33.8Very low42.4Very low113 Ų113107.9 Ų107.979%0.7958%0.583SS**SBendtrans-160.3-0.3168.357.40000120.2A593A593-S595 PolarHBondContact O-N 2.88Å
596S31.6Very low44.7Very low70 Ų70102.5 Ų102.549%0.4956%0.561SS.*  trans-111.3102.7176.765.80000111.7D598S596-D598 PolarHBondContact O-N 2.93Å
597T33.9Very low47.1Very low144 Ų14498 Ų9888%0.88355%0.552SS**THydrogen-bonded Turntrans-68.515.417442.40000114.8
598D42Very low49.3Very low142 Ų14292.3 Ų92.376%0.75953%0.529SS*.THydrogen-bonded Turntrans-120.726.8-174.8-82.9-21.2000113.5S596 P600S596-D598 PolarHBondContact O-N 2.93Å; D598-P600 WeakPolarHBondContact O-CD 3.48Å
599M41.3Very low51.6Low118 Ų11888.5 Ų88.558%0.58151%0.506SS*.  trans-82.6115.5164.9-77.6-147.2-6300109.8
600P49.1Very low54Low62 Ų6286.8 Ų86.840%0.40350%0.502SS..  trans-62.1138.5-176.9-18.230.5000111.6D598D598-P600 WeakPolarHBondContact O-CD 3.48Å
601S55.2Low56.4Low63 Ų6385.1 Ų85.144%0.44150%0.496SS..  trans-64.7146.1-170.667.50000112.8V603 D604S601-V603 PolarHBondContact O-N 3.46Å; S601-V603 VanDerWaalsContact OG-CB 3.31Å; S601-V603 WeakPolarHBondContact OG-CB 3.13Å; S601-V603 WeakPolarHBondContact OG-CG2 3.19Å; S601-D604 PolarHBondContact O-N 2.84Å; S601-D604 VanDerWaalsContact O-N 3.1Å
602E61.9Low58.7Low135 Ų13579.3 Ų79.363%0.63147%0.465SS*.Hα-helixtrans-45.2-20.9169.1-168.5174.2171.800113.8K421 E606K421-E602 IonicContact NZ-OE1 3.57Å; E602-E606 WeakPolarHBondContact O-CB 3.39Å; E602-E606 PolarHBondContact O-N 3.09Å; E602-E606 VanDerWaalsContact O-N 3.12Å
603V72.5Confident60.9Low85 Ų8575.7 Ų75.752%0.51544%0.441SS..Hα-helixtrans-62.2-39.4178.1-172.10000113.7S601 E606 T607S601-V603 PolarHBondContact O-N 3.46Å; S601-V603 VanDerWaalsContact OG-CB 3.31Å; S601-V603 WeakPolarHBondContact OG-CB 3.13Å; S601-V603 WeakPolarHBondContact OG-CG2 3.19Å; V603-E606 PolarHBondContact O-N 2.96Å; V603-T607 WeakPolarHBondContact O-CB 3.2Å; V603-T607 PolarHBondContact O-N 3.29Å; V603-T607 PolarHBondContact O-OG1 3.48Å
604D75.3Confident63.1Low70 Ų7077 Ų7737%0.37444%0.443SS..Hα-helixtrans-67.2-44.6-177.6-73.8-25.1000110.7S601 E606 T607 I608S601-D604 PolarHBondContact O-N 2.84Å; S601-D604 VanDerWaalsContact O-N 3.1Å; D604-E606 VanDerWaalsContact C-N 3.33Å; D604-E606 PolarHBondContact O-N 3.25Å; D604-T607 PolarHBondContact O-N 3.45Å; D604-I608 VanDerWaalsContact O-CG1 3.28Å; D604-I608 WeakPolarHBondContact O-CG1 3.47Å; D604-I608 PolarHBondContact O-N 2.88Å
605I79.5Confident64.9Low13 Ų1376.4 Ų76.47%0.06743%0.43CS..Hα-helixtrans-64.6-40.9177.1-65.4177.9000110.2F420 K421 A424 L425 F437 T607 I608 L609F420-I605 HydrophobicContact CD1-CG2 4.38Å; F420-I605 HydrophobicContact CE1-CG2 4.21Å; K421-I605 HydrophobicContact CB-CG2 4.42Å; K421-I605 HydrophobicContact CG-CG2 4.05Å; A424-I605 HydrophobicContact CB-CD1 4.08Å; A424-I605 HydrophobicContact CB-CG1 4.25Å; A424-I605 HydrophobicContact CB-CG2 3.87Å; L425-I605 HydrophobicContact CB-CD1 4.43Å; L425-I605 HydrophobicContact CD2-CD1 3.39Å; L425-I605 HydrophobicContact CG-CD1 3.56Å; F437-I605 HydrophobicContact CE1-CG1 4.18Å; F437-I605 HydrophobicContact CZ-CG1 4.28Å; I605-T607 VanDerWaalsContact C-N 3.35Å; I605-I608 PolarHBondContact O-N 3.45Å; I605-L609 VanDerWaalsContact O-CB 3.22Å; I605-L609 WeakPolarHBondContact O-CB 3.49Å; I605-L609 PolarHBondContact O-N 3.35Å
606E81.7Confident66.4Low89 Ų8972.5 Ų72.542%0.41640%0.404SS..Hα-helixtrans-65-38.1176.8-173.9161.1-151.400112.5E602 V603 D604 L609 N610E602-E606 WeakPolarHBondContact O-CB 3.39Å; E602-E606 PolarHBondContact O-N 3.09Å; E602-E606 VanDerWaalsContact O-N 3.12Å; V603-E606 PolarHBondContact O-N 2.96Å; D604-E606 VanDerWaalsContact C-N 3.33Å; D604-E606 PolarHBondContact O-N 3.25Å; E606-L609 PolarHBondContact O-N 3Å; E606-N610 WeakPolarHBondContact O-CB 3.46Å; E606-N610 PolarHBondContact O-N 3.15Å; E606-N610 PolarHBondContact O-ND2 3.4Å; E606-N610 VanDerWaalsContact O-ND2 3.17Å
607T82.9Confident68Low71 Ų7173 Ų7344%0.43640%0.399SS..Hα-helixtrans-64-49.3175.2-58.20000111.3V603 D604 I605 L609 N610 I611V603-T607 WeakPolarHBondContact O-CB 3.2Å; V603-T607 PolarHBondContact O-N 3.29Å; V603-T607 PolarHBondContact O-OG1 3.48Å; D604-T607 PolarHBondContact O-N 3.45Å; I605-T607 VanDerWaalsContact C-N 3.35Å; T607-L609 VanDerWaalsContact C-N 3.33Å; T607-L609 PolarHBondContact O-N 2.79Å; T607-N610 PolarHBondContact O-N 3.3Å; T607-I611 HydrophobicContact CG2-CD1 4.11Å; T607-I611 WeakPolarHBondContact O-CG1 3.48Å; T607-I611 PolarHBondContact O-N 2.95Å; T607-I611 VanDerWaalsContact O-N 3.11Å
608I81Confident69.2Low38 Ų3871.9 Ų71.920%0.19538%0.383CS..Hα-helixtrans-56-49.7175.3-70.4170.2000109.9P391 F420 F437 W439 D604 I605 N610 I611 I612P391-I608 HydrophobicContact CB-CG2 3.93Å; P391-I608 HydrophobicContact CG-CG2 4.17Å; F420-I608 HydrophobicContact CE1-CG2 4.27Å; F420-I608 HydrophobicContact CZ-CG2 3.88Å; F437-I608 HydrophobicContact CD2-CD1 4.38Å; F437-I608 HydrophobicContact CE2-CD1 3.6Å; F437-I608 HydrophobicContact CZ-CD1 3.75Å; W439-I608 HydrophobicContact CH2-CD1 4.49Å; W439-I608 HydrophobicContact CH2-CG2 4.44Å; W439-I608 HydrophobicContact CZ2-CD1 4.4Å; D604-I608 VanDerWaalsContact O-CG1 3.28Å; D604-I608 WeakPolarHBondContact O-CG1 3.47Å; D604-I608 PolarHBondContact O-N 2.88Å; I605-I608 PolarHBondContact O-N 3.45Å; I608-N610 PolarHBondContact O-N 3.39Å; I608-I611 PolarHBondContact O-N 3.12Å; I608-I612 HydrophobicContact CG2-CD1 3.44Å; I608-I612 VanDerWaalsContact CG2-CD1 3.44Å; I608-I612 HydrophobicContact CG2-CG1 4.48Å; I608-I612 WeakPolarHBondContact O-CD1 3.48Å; I608-I612 WeakPolarHBondContact O-CG1 3.44Å; I608-I612 PolarHBondContact O-N 2.96Å; I608-I612 VanDerWaalsContact O-N 3.09Å
609L82Confident69.9Low4 Ų469.4 Ų69.42%0.02137%0.367CS..Hα-helixtrans-57.9-45.4179.7-173.261.3000112.3L395 K417 F420 K421 I605 E606 T607 I612 F613L395-L609 HydrophobicContact CD1-CD1 4.11Å; K417-L609 HydrophobicContact CB-CD2 4.02Å; K417-L609 HydrophobicContact CD-CD2 4.41Å; K417-L609 HydrophobicContact CG-CD2 3.98Å; F420-L609 HydrophobicContact CB-CD1 3.9Å; F420-L609 HydrophobicContact CD1-CB 4.24Å; F420-L609 HydrophobicContact CD1-CD1 3.43Å; F420-L609 VanDerWaalsContact CD1-CD1 3.43Å; F420-L609 HydrophobicContact CD1-CG 4.28Å; F420-L609 HydrophobicContact CD2-CD1 4.3Å; F420-L609 HydrophobicContact CE1-CB 4.16Å; F420-L609 HydrophobicContact CE1-CD1 3.96Å; F420-L609 HydrophobicContact CG-CD1 3.59Å; K421-L609 HydrophobicContact CG-CD2 4.27Å; I605-L609 VanDerWaalsContact O-CB 3.22Å; I605-L609 WeakPolarHBondContact O-CB 3.49Å; I605-L609 PolarHBondContact O-N 3.35Å; E606-L609 PolarHBondContact O-N 3Å; T607-L609 VanDerWaalsContact C-N 3.33Å; T607-L609 PolarHBondContact O-N 2.79Å; L609-I612 PolarHBondContact O-N 2.89Å; L609-F613 HydrophobicContact CD1-CD2 3.53Å; L609-F613 HydrophobicContact CD1-CE2 3.44Å; L609-F613 VanDerWaalsContact CD1-CE2 3.44Å; L609-F613 HydrophobicContact CG-CD2 3.85Å; L609-F613 HydrophobicContact CG-CE2 4.02Å; L609-F613 WeakPolarHBondContact O-CB 3.36Å; L609-F613 WeakPolarHBondContact O-CD2 3.37Å; L609-F613 PolarHBondContact O-N 3Å
610N81.5Confident70.4Confident79 Ų7966 Ų6642%0.42236%0.362SS..Hα-helixtrans-64.1-41.8-179.9-74.6-28.9000112.1E606 T607 I608 V614E606-N610 WeakPolarHBondContact O-CB 3.46Å; E606-N610 PolarHBondContact O-N 3.15Å; E606-N610 PolarHBondContact O-ND2 3.4Å; E606-N610 VanDerWaalsContact O-ND2 3.17Å; T607-N610 PolarHBondContact O-N 3.3Å; I608-N610 PolarHBondContact O-N 3.39Å; N610-V614 WeakPolarHBondContact O-CG2 3.31Å; N610-V614 PolarHBondContact O-N 3.13Å
611I81.3Confident70.2Confident108 Ų10871.2 Ų71.255%0.55437%0.374SS*.Hα-helixtrans-61.7-46.4176.7-66.7166.1000110.8T607 I608 V614 Q615T607-I611 HydrophobicContact CG2-CD1 4.11Å; T607-I611 WeakPolarHBondContact O-CG1 3.48Å; T607-I611 PolarHBondContact O-N 2.95Å; T607-I611 VanDerWaalsContact O-N 3.11Å; I608-I611 PolarHBondContact O-N 3.12Å; I611-V614 PolarHBondContact O-N 2.92Å; I611-Q615 PolarHBondContact O-N 3.15Å
612I77.1Confident69.6Low9 Ų971 Ų715%0.04637%0.372CS..Hα-helixtrans-72.8-37.6-175.9-57.3150.7000111.4P391 L392 L395 F420 I608 L609 V614 Q615 A616P391-I612 HydrophobicContact CB-CD1 3.08Å; P391-I612 HydrophobicContact CB-CG1 3.96Å; P391-I612 HydrophobicContact CG-CD1 4.25Å; L392-I612 HydrophobicContact CB-CG2 3.94Å; L392-I612 HydrophobicContact CD1-CG2 3.64Å; L392-I612 HydrophobicContact CG-CG2 4.4Å; L395-I612 HydrophobicContact CB-CG2 4.29Å; L395-I612 HydrophobicContact CD2-CB 4.39Å; L395-I612 HydrophobicContact CD2-CG2 3.56Å; F420-I612 HydrophobicContact CE2-CD1 4.11Å; F420-I612 HydrophobicContact CZ-CD1 3.84Å; I608-I612 HydrophobicContact CG2-CD1 3.44Å; I608-I612 VanDerWaalsContact CG2-CD1 3.44Å; I608-I612 HydrophobicContact CG2-CG1 4.48Å; I608-I612 WeakPolarHBondContact O-CD1 3.48Å; I608-I612 WeakPolarHBondContact O-CG1 3.44Å; I608-I612 PolarHBondContact O-N 2.96Å; I608-I612 VanDerWaalsContact O-N 3.09Å; L609-I612 PolarHBondContact O-N 2.89Å; I612-V614 VanDerWaalsContact C-N 3.25Å; I612-V614 PolarHBondContact O-N 3.21Å; I612-Q615 WeakPolarHBondContact O-CB 3.33Å; I612-Q615 PolarHBondContact O-N 3.43Å; I612-Q615 VanDerWaalsContact O-N 3.15Å; I612-A616 WeakPolarHBondContact O-CB 3.42Å; I612-A616 PolarHBondContact O-N 3.39Å
613F75.7Confident68.5Low24 Ų2467.5 Ų67.511%0.10537%0.366CS..Hα-helixtrans-60.2-40.3175.7-102.9-88.7000111.1L395 R413 V416 K417 L609 E617L395-F613 HydrophobicContact CD1-CD2 4.15Å; L395-F613 HydrophobicContact CD1-CE2 3.47Å; L395-F613 VanDerWaalsContact CD1-CE2 3.47Å; L395-F613 HydrophobicContact CD1-CZ 3.98Å; L395-F613 HydrophobicContact CD2-CD2 4.11Å; L395-F613 HydrophobicContact CD2-CE2 4.15Å; L395-F613 HydrophobicContact CG-CE2 4.46Å; R413-F613 HydrophobicContact CG-CE1 4.17Å; V416-F613 HydrophobicContact CG1-CZ 4.02Å; K417-F613 HydrophobicContact CD-CE2 4.42Å; K417-F613 HydrophobicContact CD-CZ 4.42Å; K417-F613 HydrophobicContact CG-CD2 4.44Å; K417-F613 HydrophobicContact CG-CE2 3.49Å; K417-F613 VanDerWaalsContact CG-CE2 3.49Å; K417-F613 HydrophobicContact CG-CZ 3.54Å; L609-F613 HydrophobicContact CD1-CD2 3.53Å; L609-F613 HydrophobicContact CD1-CE2 3.44Å; L609-F613 VanDerWaalsContact CD1-CE2 3.44Å; L609-F613 HydrophobicContact CG-CD2 3.85Å; L609-F613 HydrophobicContact CG-CE2 4.02Å; L609-F613 WeakPolarHBondContact O-CB 3.36Å; L609-F613 WeakPolarHBondContact O-CD2 3.37Å; L609-F613 PolarHBondContact O-N 3Å; F613-E617 WeakPolarHBondContact O-CB 3.41Å; F613-E617 WeakPolarHBondContact O-CG 3.4Å; F613-E617 PolarHBondContact O-N 3.29Å; F613-E617 VanDerWaalsContact O-N 3.08Å
614V74.1Confident66.9Low80 Ų8066.9 Ų66.949%0.48537%0.365SS..Hα-helixtrans-62.8-46.6173.4172.30000110.3N610 I611 I612 E617 H618N610-V614 WeakPolarHBondContact O-CG2 3.31Å; N610-V614 PolarHBondContact O-N 3.13Å; I611-V614 PolarHBondContact O-N 2.92Å; I612-V614 VanDerWaalsContact C-N 3.25Å; I612-V614 PolarHBondContact O-N 3.21Å; V614-E617 PolarHBondContact O-N 2.82Å; V614-H618 PolarHBondContact O-CD2 3.33Å; V614-H618 PolarHBondContact O-N 2.85Å
615Q69.3Low64.9Low88 Ų8870.4 Ų70.441%0.41138%0.377SS..Hα-helixtrans-59-49177.2-176.7178.7-17.800112.8I611 I612 E617 H618 E619I611-Q615 PolarHBondContact O-N 3.15Å; I612-Q615 WeakPolarHBondContact O-CB 3.33Å; I612-Q615 PolarHBondContact O-N 3.43Å; I612-Q615 VanDerWaalsContact O-N 3.15Å; Q615-E617 VanDerWaalsContact C-N 3.3Å; Q615-E617 PolarHBondContact O-N 2.89Å; Q615-H618 PolarHBondContact O-N 3.09Å; Q615-H618 VanDerWaalsContact O-N 3.15Å; Q615-E619 PolarHBondContact NE2-OE1 3.45Å; Q615-E619 PolarHBondContact O-N 3.11Å
616A64.7Low62.8Low31 Ų3174.1 Ų74.126%0.25640%0.398SS..Hα-helixtrans-62.8-35.9-179.400000112.2L392 L395 I612 G620L392-A616 HydrophobicContact CD1-CB 4.09Å; L395-A616 HydrophobicContact CD2-CB 4.37Å; I612-A616 WeakPolarHBondContact O-CB 3.42Å; I612-A616 PolarHBondContact O-N 3.39Å; A616-G620 PolarHBondContact O-N 3.4Å; A616-G620 VanDerWaalsContact O-N 3.13Å
617E66.6Low60.5Low79 Ų7973.1 Ų73.137%0.36941%0.405SS..Hα-helixtrans-70-37.7173.9-74.9-176.2178.200112.5R413 F613 V614 Q615 R621R413-E617 IonicContact CZ-OE1 3.18Å; R413-E617 IonicContact NH1-OE1 2.75Å; R413-E617 PolarHBondContact NH1-OE1 3.12Å; R413-E617 IonicContact NH2-OE1 2.72Å; R413-E617 PolarHBondContact NH2-OE1 2.78Å; F613-E617 WeakPolarHBondContact O-CB 3.41Å; F613-E617 WeakPolarHBondContact O-CG 3.4Å; F613-E617 PolarHBondContact O-N 3.29Å; F613-E617 VanDerWaalsContact O-N 3.08Å; V614-E617 PolarHBondContact O-N 2.82Å; Q615-E617 VanDerWaalsContact C-N 3.3Å; Q615-E617 PolarHBondContact O-N 2.89Å; E617-R621 PolarHBondContact O-N 3.37Å
618H58.4Low58.3Low122 Ų12273.2 Ų73.257%0.56541%0.408SS*.Hα-helixtrans-65.6-43.8174.6-88.6-76.3000112.2V614 Q615 R621 S622V614-H618 PolarHBondContact O-CD2 3.33Å; V614-H618 PolarHBondContact O-N 2.85Å; Q615-H618 PolarHBondContact O-N 3.09Å; Q615-H618 VanDerWaalsContact O-N 3.15Å; H618-R621 PolarHBondContact O-N 3.28Å; H618-S622 WeakPolarHBondContact O-CB 3.42Å; H618-S622 PolarHBondContact O-N 2.92Å
619E56.3Low56.1Low90 Ų9074.6 Ų74.642%0.42142%0.418SS..Hα-helixtrans-61.5-44.6176.7-75.2177.2-16600111.1Q615 R621 S622 A623Q615-E619 PolarHBondContact NE2-OE1 3.45Å; Q615-E619 PolarHBondContact O-N 3.11Å; E619-R621 PolarHBondContact O-N 3.29Å; E619-S622 PolarHBondContact O-N 2.94Å; E619-S622 PolarHBondContact O-OG 3.1Å; E619-A623 PolarHBondContact O-N 2.74Å
620G52.9Low53.6Low45 Ų4581.5 Ų81.546%0.46445%0.448SS..Hα-helixtrans-58.9-41.5174.100000113.9A616 S624A616-G620 PolarHBondContact O-N 3.4Å; A616-G620 VanDerWaalsContact O-N 3.13Å; G620-S624 PolarHBondContact O-N 3.17Å
621R45.2Very low51.3Low173 Ų17382 Ų8265%0.65346%0.464SS*.Hα-helixtrans-71.5-33.5175-78.6179.4176.4174.50.8113E617 H618 E619 S624 K625E617-R621 PolarHBondContact O-N 3.37Å; H618-R621 PolarHBondContact O-N 3.28Å; E619-R621 PolarHBondContact O-N 3.29Å; R621-S624 PolarHBondContact O-OG 3.03Å; R621-K625 WeakPolarHBondContact O-CB 3.33Å; R621-K625 PolarHBondContact O-N 3.38Å
622S42.4Very low49Very low57 Ų5781.6 Ų81.640%0.39947%0.47SS..Hα-helixtrans-67.6-38.7175.487.10000111.4H618 E619 S624 K625 N626H618-S622 WeakPolarHBondContact O-CB 3.42Å; H618-S622 PolarHBondContact O-N 2.92Å; E619-S622 PolarHBondContact O-N 2.94Å; E619-S622 PolarHBondContact O-OG 3.1Å; S622-S624 VanDerWaalsContact C-N 3.35Å; S622-K625 PolarHBondContact O-N 3.23Å; S622-N626 WeakPolarHBondContact O-CB 3.35Å; S622-N626 PolarHBondContact O-N 2.99Å
623A38.6Very low46.8Very low62 Ų6285.1 Ų85.151%0.51250%0.496SS..Hα-helixtrans-65-39.9177.100000111.2E619 A627E619-A623 PolarHBondContact O-N 2.74Å; A623-A627 PolarHBondContact O-N 3.35Å; A623-A627 VanDerWaalsContact O-N 3.09Å
624S37.5Very low44.7Very low72 Ų7287 Ų8750%0.50352%0.522SS..Hα-helixtrans-69.2-40.7174.178.70000112.6G620 R621 S622 A627 S628G620-S624 PolarHBondContact O-N 3.17Å; R621-S624 PolarHBondContact O-OG 3.03Å; S622-S624 VanDerWaalsContact C-N 3.35Å; S624-A627 WeakPolarHBondContact O-CB 3.47Å; S624-A627 PolarHBondContact O-N 3.08Å; S624-S628 PolarHBondContact O-N 3.37Å; S624-S628 VanDerWaalsContact O-N 3.11Å; S624-S628 PolarHBondContact O-OG 3Å
625K33.8Very low42.7Very low144 Ų14492.2 Ų92.263%0.62654%0.541SS*.Hα-helixtrans-65.8-37.5174.6-83.2-172.8176.4-176.50113.3R621 S622 A627 S628 T629R621-K625 WeakPolarHBondContact O-CB 3.33Å; R621-K625 PolarHBondContact O-N 3.38Å; S622-K625 PolarHBondContact O-N 3.23Å; K625-A627 VanDerWaalsContact C-N 3.31Å; K625-S628 PolarHBondContact O-N 3.2Å; K625-S628 PolarHBondContact O-OG 2.75Å; K625-T629 WeakPolarHBondContact O-CB 3.49Å; K625-T629 PolarHBondContact O-N 3.06Å; K625-T629 PolarHBondContact O-OG1 2.85Å
626N35.5Very low41.1Very low92 Ų9293.8 Ų93.849%0.49256%0.562SS.*Hα-helixtrans-71.9-27.1176.2-81-22.6000112.3S622 K630S622-N626 WeakPolarHBondContact O-CB 3.35Å; S622-N626 PolarHBondContact O-N 2.99Å; N626-K630 PolarHBondContact O-N 2.97Å
627A34.4Very low39.7Very low68 Ų6897 Ų9756%0.56258%0.583SS**Hα-helixtrans-69-35.3169.600000111.7A623 S624 K625A623-A627 PolarHBondContact O-N 3.35Å; A623-A627 VanDerWaalsContact O-N 3.09Å; S624-A627 WeakPolarHBondContact O-CB 3.47Å; S624-A627 PolarHBondContact O-N 3.08Å; K625-A627 VanDerWaalsContact C-N 3.31Å
628S35.2Very low38.3Very low73 Ų73101.5 Ų101.551%0.5160%0.603SS.*Hα-helixtrans-84.9-36.9178.963.90000114.7S624 K625 A631S624-S628 PolarHBondContact O-N 3.37Å; S624-S628 VanDerWaalsContact O-N 3.11Å; S624-S628 PolarHBondContact O-OG 3Å; K625-S628 PolarHBondContact O-N 3.2Å; K625-S628 PolarHBondContact O-OG 2.75Å; S628-A631 WeakPolarHBondContact O-CB 3.49Å; S628-A631 PolarHBondContact O-N 2.72Å
629T35.2Very low37.3Very low67 Ų67100 Ų10041%0.41160%0.604SS.*Hα-helixtrans-78-27.4-177.945.70000113.9K625 A631 S632 S633K625-T629 WeakPolarHBondContact O-CB 3.49Å; K625-T629 PolarHBondContact O-N 3.06Å; K625-T629 PolarHBondContact O-OG1 2.85Å; T629-A631 PolarHBondContact O-N 2.99Å; T629-S632 PolarHBondContact O-N 3.27Å; T629-S632 PolarHBondContact O-OG 3.22Å; T629-S633 PolarHBondContact O-N 2.99Å
630K30.6Very low36.5Very low149 Ų149106.7 Ų106.765%0.64863%0.626SS**THydrogen-bonded Turntrans-74.3-11.7169.8-84.1-172.2175.4-179.20113.6N626N626-K630 PolarHBondContact O-N 2.97Å
631A32.7Very low35.8Very low90 Ų90108.4 Ų108.474%0.74462%0.621SS**THydrogen-bonded Turntrans-74-15.8164.900000112.1S628 T629S628-A631 WeakPolarHBondContact O-CB 3.49Å; S628-A631 PolarHBondContact O-N 2.72Å; T629-A631 PolarHBondContact O-N 2.99Å
632S33.8Very low36.1Very low98 Ų98104.7 Ų104.769%0.68562%0.617SS**THydrogen-bonded Turntrans-111-7.1-179.762.40000115.3T629T629-S632 PolarHBondContact O-N 3.27Å; T629-S632 PolarHBondContact O-OG 3.22Å
633S29.9Very low36.8Very low84 Ų84108.3 Ų108.359%0.58763%0.632SS**SBendtrans-103.393.2179.770.50000112.5T629T629-S633 PolarHBondContact O-N 2.99Å
634G31.6Very low37.6Very low64 Ų64114.6 Ų114.666%0.6664%0.643SS**SBendtrans133.8117.7156.700000115
635Q32.8Very low38.4Very low189 Ų189115.5 Ų115.588%0.88364%0.639SS**SBendtrans80.6123.1169.2-62.5178.3-48.300115.7S637Q635-S637 PolarHBondContact O-N 3.11Å
636S34.6Very low39.5Very low121 Ų121113.5 Ų113.585%0.84663%0.632SS**  trans-30.9106167.148.70000111E638S636-E638 PolarHBondContact O-N 2.89Å
637S35.7Very low40.9Very low99 Ų99117.7 Ų117.769%0.69264%0.642SS**  trans-65.9105.2178.650.80000108.8Q635Q635-S637 PolarHBondContact O-N 3.11Å
638E37.3Very low42.5Very low173 Ų173119.6 Ų119.681%0.80864%0.639SS**  trans-53.4131.5143.7-82.4-177.5157.800106.8S636 W640S636-E638 PolarHBondContact O-N 2.89Å; E638-W640 PolarHBondContact O-N 3.48Å; E638-W640 VanDerWaalsContact O-N 3.11Å
639P37.8Very low44.1Very low90 Ų90119.6 Ų119.658%0.58463%0.633SS**  trans-54.9124.1-17820.1-29.6000108.7F641P639-F641 CarbonylContact O-C 3.59Å; P639-F641 PolarHBondContact O-N 3.3Å
640W39.5Very low45.9Very low231 Ų231118.9 Ų118.988%0.87563%0.634SS**SBendtrans-55.8-16.6-179.4-9042.2000113.8E638E638-W640 PolarHBondContact O-N 3.48Å; E638-W640 VanDerWaalsContact O-N 3.11Å
641F37.5Very low48.2Very low81 Ų81116.9 Ų116.936%0.35563%0.63SS.*SBendtrans-115.8123176.6-59.8-73.2000107.5P639 Q645 Q646 I649P639-F641 CarbonylContact O-C 3.59Å; P639-F641 PolarHBondContact O-N 3.3Å; F641-Q645 HydrophobicContact CB-CB 4.05Å; F641-Q645 HydrophobicContact CD1-CB 3.86Å; F641-Q645 HydrophobicContact CG-CB 4.44Å; F641-Q646 HydrophobicContact CB-CG 3.54Å; F641-Q646 HydrophobicContact CG-CG 4.34Å; F641-I649 HydrophobicContact CD1-CD1 3.89Å; F641-I649 HydrophobicContact CE1-CD1 3.61Å; F641-I649 HydrophobicContact CG-CD1 4.47Å; F641-I649 HydrophobicContact CZ-CD1 3.99Å
642T52.8Low50.4Low94 Ų94119.8 Ų119.858%0.57762%0.622SS**  trans-56.4151.115950.70000108.5R644 Q645 Q646T642-R644 PolarHBondContact O-N 2.66Å; T642-Q645 PolarHBondContact O-N 3.02Å; T642-Q646 PolarHBondContact O-N 2.82Å
643D57.2Low52.8Low134 Ų134122.9 Ų122.972%0.71762%0.619SS**Hα-helixtrans-49.8-29179.1-69.1-37000112.6Y647D643-Y647 PolarHBondContact O-N 3.01Å
644R55.3Low55.5Low194 Ų194122.5 Ų122.573%0.73261%0.614SS**Hα-helixtrans-65.4-43.2174.5-165.4171.5-173.71604113.5T642 Y647 E648T642-R644 PolarHBondContact O-N 2.66Å; R644-Y647 WeakPolarHBondContact O-CB 3.37Å; R644-Y647 PolarHBondContact O-N 3.01Å; R644-E648 PolarHBondContact O-N 3.05Å
645Q54.1Low58.1Low90 Ų90122.7 Ų122.742%0.42160%0.604SS.*Hα-helixtrans-73-32.7179.4-72.4-158.1-43.500112.7F641 T642 Y647 E648 I649F641-Q645 HydrophobicContact CB-CB 4.05Å; F641-Q645 HydrophobicContact CD1-CB 3.86Å; F641-Q645 HydrophobicContact CG-CB 4.44Å; T642-Q645 PolarHBondContact O-N 3.02Å; Q645-Y647 VanDerWaalsContact C-N 3.29Å; Q645-Y647 PolarHBondContact O-N 3.31Å; Q645-E648 PolarHBondContact O-N 3.25Å; Q645-I649 WeakPolarHBondContact O-CG1 3.49Å; Q645-I649 PolarHBondContact O-N 2.82Å
646Q57Low60.7Low102 Ų102116.4 Ų116.448%0.47758%0.576SS.*Hα-helixtrans-62.8-40.2171.6-67.6-162.9-8.200111.2F641 T642 I649 A650F641-Q646 HydrophobicContact CB-CG 3.54Å; F641-Q646 HydrophobicContact CG-CG 4.34Å; T642-Q646 PolarHBondContact O-N 2.82Å; Q646-I649 PolarHBondContact O-N 3.21Å; Q646-A650 WeakPolarHBondContact O-CB 3.43Å; Q646-A650 PolarHBondContact O-N 2.96Å
647Y65Low63.4Low180 Ų180113.2 Ų113.271%0.70656%0.557SS**Hα-helixtrans-61.8-42.5173.7-119.4-85.6000112.2D643 R644 Q645 A650 L651D643-Y647 PolarHBondContact O-N 3.01Å; R644-Y647 WeakPolarHBondContact O-CB 3.37Å; R644-Y647 PolarHBondContact O-N 3.01Å; Q645-Y647 VanDerWaalsContact C-N 3.29Å; Q645-Y647 PolarHBondContact O-N 3.31Å; Y647-A650 PolarHBondContact O-N 2.91Å; Y647-L651 WeakPolarHBondContact O-CB 3.44Å; Y647-L651 PolarHBondContact O-N 3.44Å
648E67.9Low66Low108 Ų108113.3 Ų113.351%0.50555%0.549SS..Hα-helixtrans-65.6-40178.2-74.5177-177.200112.7R644 Q645 L651 Y652R644-E648 PolarHBondContact O-N 3.05Å; Q645-E648 PolarHBondContact O-N 3.25Å; E648-L651 PolarHBondContact O-N 3.11Å; E648-Y652 WeakPolarHBondContact O-CB 3.37Å; E648-Y652 PolarHBondContact O-N 2.92Å
649I67.8Low68.5Low73 Ų73110.4 Ų110.437%0.37454%0.539SS..Hα-helixtrans-66.3-43.3175.7-68168.1000110.6F641 Q645 Q646 L651 Y652 W653F641-I649 HydrophobicContact CD1-CD1 3.89Å; F641-I649 HydrophobicContact CE1-CD1 3.61Å; F641-I649 HydrophobicContact CG-CD1 4.47Å; F641-I649 HydrophobicContact CZ-CD1 3.99Å; Q645-I649 WeakPolarHBondContact O-CG1 3.49Å; Q645-I649 PolarHBondContact O-N 2.82Å; Q646-I649 PolarHBondContact O-N 3.21Å; I649-L651 VanDerWaalsContact C-N 3.31Å; I649-L651 PolarHBondContact O-N 2.99Å; I649-Y652 WeakPolarHBondContact O-CB 3.45Å; I649-Y652 PolarHBondContact O-N 3.26Å; I649-W653 PolarHBondContact O-N 3.2Å
650A73.1Confident71Confident53 Ų53109.7 Ų109.744%0.43853%0.532SS..Hα-helixtrans-62.1-40.6174.800000111.3Q646 Y647 Y652 W653 T654Q646-A650 WeakPolarHBondContact O-CB 3.43Å; Q646-A650 PolarHBondContact O-N 2.96Å; Y647-A650 PolarHBondContact O-N 2.91Å; A650-Y652 VanDerWaalsContact C-N 3.35Å; A650-W653 PolarHBondContact O-N 3.35Å; A650-T654 WeakPolarHBondContact O-CB 3.39Å; A650-T654 WeakPolarHBondContact O-CG2 3.43Å; A650-T654 PolarHBondContact O-N 3.2Å; A650-T654 PolarHBondContact O-OG1 2.99Å
651L79.1Confident73.5Confident107 Ų107104.2 Ų104.256%0.5652%0.518SS*.Hα-helixtrans-62.8-40.5174.9-143.783.2000111.9Y647 E648 I649 T654 C655Y647-L651 WeakPolarHBondContact O-CB 3.44Å; Y647-L651 PolarHBondContact O-N 3.44Å; E648-L651 PolarHBondContact O-N 3.11Å; I649-L651 VanDerWaalsContact C-N 3.31Å; I649-L651 PolarHBondContact O-N 2.99Å; L651-T654 VanDerWaalsContact CA-OG1 3.22Å; L651-T654 WeakPolarHBondContact CA-OG1 3.38Å; L651-T654 PolarHBondContact O-N 3.32Å; L651-T654 PolarHBondContact O-OG1 2.85Å; L651-C655 WeakPolarHBondContact O-CB 3.48Å; L651-C655 PolarHBondContact O-N 3.06Å; L651-C655 PolarHBondContact O-SG 3.27Å
652Y78.5Confident76Confident150 Ų150107.7 Ų107.759%0.58853%0.533SS*.Hα-helixtrans-63.2-48.2177.6-176.3-99.5000112.1E648 I649 A650 C655 I656E648-Y652 WeakPolarHBondContact O-CB 3.37Å; E648-Y652 PolarHBondContact O-N 2.92Å; I649-Y652 WeakPolarHBondContact O-CB 3.45Å; I649-Y652 PolarHBondContact O-N 3.26Å; A650-Y652 VanDerWaalsContact C-N 3.35Å; Y652-C655 WeakPolarHBondContact O-CB 3.39Å; Y652-C655 PolarHBondContact O-N 3.48Å; Y652-I656 HydrophobicContact CD1-CD1 3.86Å; Y652-I656 HydrophobicContact CE1-CD1 3.31Å; Y652-I656 HydrophobicContact CE1-CG1 4.37Å; Y652-I656 PolarHBondContact O-N 3.48Å
653W84.9Confident77.8Confident164 Ų164108.6 Ų108.662%0.62153%0.534SS*.Hα-helixtrans-68.2-34.9178.7-76.9110.4000113.1I649 A650 I656 A657I649-W653 PolarHBondContact O-N 3.2Å; A650-W653 PolarHBondContact O-N 3.35Å; W653-I656 HydrophobicContact CE3-CD1 4.3Å; W653-I656 HydrophobicContact CZ3-CD1 4.39Å; W653-I656 PolarHBondContact O-N 3.03Å; W653-A657 WeakPolarHBondContact O-CB 3.38Å; W653-A657 PolarHBondContact O-N 3.41Å
654T86.2Confident79.3Confident76 Ų76106.7 Ų106.747%0.46652%0.523SS..Hα-helixtrans-67.1-38.6173.245.60000112.1A650 L651 A657 L658A650-T654 WeakPolarHBondContact O-CB 3.39Å; A650-T654 WeakPolarHBondContact O-CG2 3.43Å; A650-T654 PolarHBondContact O-N 3.2Å; A650-T654 PolarHBondContact O-OG1 2.99Å; L651-T654 VanDerWaalsContact CA-OG1 3.22Å; L651-T654 WeakPolarHBondContact CA-OG1 3.38Å; L651-T654 PolarHBondContact O-N 3.32Å; L651-T654 PolarHBondContact O-OG1 2.85Å; T654-A657 PolarHBondContact O-N 3.31Å; T654-L658 WeakPolarHBondContact O-CB 3.36Å; T654-L658 WeakPolarHBondContact O-CG 3.22Å; T654-L658 PolarHBondContact O-N 2.86Å
655C87.2Confident81Confident67 Ų67100.7 Ų100.745%0.45351%0.508SS..Hα-helixtrans-61.6-43.6171.9-77.20000112.5L651 Y652 L658 L659L651-C655 WeakPolarHBondContact O-CB 3.48Å; L651-C655 PolarHBondContact O-N 3.06Å; L651-C655 PolarHBondContact O-SG 3.27Å; Y652-C655 WeakPolarHBondContact O-CB 3.39Å; Y652-C655 PolarHBondContact O-N 3.48Å; C655-L658 PolarHBondContact O-N 2.77Å; C655-L659 PolarHBondContact O-N 2.95Å
656I87.2Confident82.4Confident57 Ų5797.9 Ų97.929%0.29250%0.503SS..Hα-helixtrans-62.3-46.1175.3-70.7175.7000110.7Y652 W653 L658 L659 V660Y652-I656 HydrophobicContact CD1-CD1 3.86Å; Y652-I656 HydrophobicContact CE1-CD1 3.31Å; Y652-I656 HydrophobicContact CE1-CG1 4.37Å; Y652-I656 PolarHBondContact O-N 3.48Å; W653-I656 HydrophobicContact CE3-CD1 4.3Å; W653-I656 HydrophobicContact CZ3-CD1 4.39Å; W653-I656 PolarHBondContact O-N 3.03Å; I656-L658 VanDerWaalsContact C-N 3.32Å; I656-L658 PolarHBondContact O-N 2.98Å; I656-L659 PolarHBondContact O-N 3.03Å; I656-V660 HydrophobicContact CG2-CG2 4.47Å; I656-V660 WeakPolarHBondContact O-CG2 3.49Å; I656-V660 PolarHBondContact O-N 3.27Å
657A90.1Very high83.7Confident55 Ų5597.1 Ų97.146%0.45550%0.501SS..Hα-helixtrans-60.9-40.517900000112.2W653 T654 V660 M661W653-A657 WeakPolarHBondContact O-CB 3.38Å; W653-A657 PolarHBondContact O-N 3.41Å; T654-A657 PolarHBondContact O-N 3.31Å; A657-V660 PolarHBondContact O-N 3.23Å; A657-M661 WeakPolarHBondContact O-CB 3.42Å; A657-M661 WeakPolarHBondContact O-CG 3.47Å; A657-M661 PolarHBondContact O-N 3.47Å
658L91.2Very high84.4Confident100 Ų10093.6 Ų93.652%0.52449%0.494SS..Hα-helixtrans-65.2-43.2174.9-74.4171000112.1T654 C655 I656 V660 M661 F662T654-L658 WeakPolarHBondContact O-CB 3.36Å; T654-L658 WeakPolarHBondContact O-CG 3.22Å; T654-L658 PolarHBondContact O-N 2.86Å; C655-L658 PolarHBondContact O-N 2.77Å; I656-L658 VanDerWaalsContact C-N 3.32Å; I656-L658 PolarHBondContact O-N 2.98Å; L658-V660 PolarHBondContact O-N 3.23Å; L658-M661 WeakPolarHBondContact O-CB 3.12Å; L658-M661 PolarHBondContact O-N 3.4Å; L658-F662 WeakPolarHBondContact O-CD2 3.35Å; L658-F662 PolarHBondContact O-N 3.25Å
659L88.3Confident84.8Confident113 Ų11393.3 Ų93.359%0.59250%0.495SS*.Hα-helixtrans-59.4-44.8176.2-97.3159.9000112.3C655 I656 M661 F662 L663C655-L659 PolarHBondContact O-N 2.95Å; I656-L659 PolarHBondContact O-N 3.03Å; L659-M661 VanDerWaalsContact C-N 3.34Å; L659-F662 PolarHBondContact O-N 2.9Å; L659-L663 PolarHBondContact O-N 3.5Å
660V91.9Very high84.9Confident75 Ų7596.1 Ų96.146%0.45551%0.51SS..Hα-helixtrans-63.9-41.5176.5174.10000110.7I656 A657 L658 L663 L664I656-V660 HydrophobicContact CG2-CG2 4.47Å; I656-V660 WeakPolarHBondContact O-CG2 3.49Å; I656-V660 PolarHBondContact O-N 3.27Å; A657-V660 PolarHBondContact O-N 3.23Å; L658-V660 PolarHBondContact O-N 3.23Å; V660-L663 PolarHBondContact O-N 3.47Å; V660-L664 HydrophobicContact CG1-CD1 4Å; V660-L664 HydrophobicContact CG1-CG 4.49Å; V660-L664 WeakPolarHBondContact O-CG 3.37Å; V660-L664 PolarHBondContact O-N 3.49Å
661M91.8Very high84.9Confident116 Ų11698.9 Ų98.957%0.57152%0.517SS*.Hα-helixtrans-61.9-44.2174.9-80.9-72.5-70.300112.5A657 L658 L659 L663 L664 V665A657-M661 WeakPolarHBondContact O-CB 3.42Å; A657-M661 WeakPolarHBondContact O-CG 3.47Å; A657-M661 PolarHBondContact O-N 3.47Å; L658-M661 WeakPolarHBondContact O-CB 3.12Å; L658-M661 PolarHBondContact O-N 3.4Å; L659-M661 VanDerWaalsContact C-N 3.34Å; M661-L663 PolarHBondContact O-N 3Å; M661-L664 PolarHBondContact O-N 3.4Å; M661-V665 WeakPolarHBondContact O-CB 3.27Å; M661-V665 VanDerWaalsContact O-CG2 3.3Å; M661-V665 WeakPolarHBondContact O-CG2 3.32Å; M661-V665 PolarHBondContact O-N 2.94Å
662F90.3Very high84.4Confident154 Ų15498.1 Ų98.168%0.67552%0.519SS*.Hα-helixtrans-63.4-40176.5-81.4-65.4000112.4L658 L659 V665 G666L658-F662 WeakPolarHBondContact O-CD2 3.35Å; L658-F662 PolarHBondContact O-N 3.25Å; L659-F662 PolarHBondContact O-N 2.9Å; F662-V665 PolarHBondContact O-N 3Å; F662-G666 PolarHBondContact O-N 3.35Å
663L88.8Confident83.3Confident113 Ų11395.2 Ų95.259%0.59252%0.52SS*.Hα-helixtrans-61.2-46.1173.8-93158.7000111.6L659 V660 M661 G666 I667L659-L663 PolarHBondContact O-N 3.5Å; V660-L663 PolarHBondContact O-N 3.47Å; M661-L663 PolarHBondContact O-N 3Å; L663-G666 PolarHBondContact O-N 3.4Å; L663-I667 VanDerWaalsContact O-CG1 3.27Å; L663-I667 WeakPolarHBondContact O-CG1 3.37Å; L663-I667 PolarHBondContact O-N 2.94Å
664L90.4Very high81.5Confident93 Ų9390.5 Ų90.549%0.48752%0.522SS..Hα-helixtrans-65-42.2178.7-72170.3000112.3V660 M661 I667 L668V660-L664 HydrophobicContact CG1-CD1 4Å; V660-L664 HydrophobicContact CG1-CG 4.49Å; V660-L664 WeakPolarHBondContact O-CG 3.37Å; V660-L664 PolarHBondContact O-N 3.49Å; M661-L664 PolarHBondContact O-N 3.4Å; L664-I667 PolarHBondContact O-N 3.23Å; L664-L668 WeakPolarHBondContact O-CB 3.25Å; L664-L668 PolarHBondContact O-N 3.05Å
665V89.5Confident79.4Confident69 Ų6996.2 Ų96.242%0.41854%0.541SS..Hα-helixtrans-65.4-40175.11730000111.1M661 F662 L668 L669M661-V665 WeakPolarHBondContact O-CB 3.27Å; M661-V665 VanDerWaalsContact O-CG2 3.3Å; M661-V665 WeakPolarHBondContact O-CG2 3.32Å; M661-V665 PolarHBondContact O-N 2.94Å; F662-V665 PolarHBondContact O-N 3Å; V665-L668 PolarHBondContact O-N 2.96Å; V665-L669 HydrophobicContact CG1-CD1 4.01Å; V665-L669 HydrophobicContact CG1-CG 4.35Å; V665-L669 WeakPolarHBondContact O-CB 3.45Å; V665-L669 WeakPolarHBondContact O-CG 3.3Å; V665-L669 PolarHBondContact O-N 3.35Å
666G83.8Confident77.2Confident30 Ų3097.8 Ų97.831%0.30955%0.552SS.*Hα-helixtrans-61.7-42.7175.300000112.6F662 L663 L669 L670F662-G666 PolarHBondContact O-N 3.35Å; L663-G666 PolarHBondContact O-N 3.4Å; G666-L669 PolarHBondContact O-N 3.36Å; G666-L670 WeakPolarHBondContact O-CG 3.46Å; G666-L670 PolarHBondContact O-N 3.29Å
667I84Confident74.9Confident87 Ų87104.4 Ų104.445%0.44658%0.579SS.*Hα-helixtrans-64.3-44.3174.4-67.6165000110.6L663 L664 L669 L670 I671L663-I667 VanDerWaalsContact O-CG1 3.27Å; L663-I667 WeakPolarHBondContact O-CG1 3.37Å; L663-I667 PolarHBondContact O-N 2.94Å; L664-I667 PolarHBondContact O-N 3.23Å; I667-L669 PolarHBondContact O-N 2.98Å; I667-L670 PolarHBondContact O-N 2.87Å; I667-I671 HydrophobicContact CG2-CD1 3.79Å; I667-I671 VanDerWaalsContact O-CG1 3.25Å; I667-I671 WeakPolarHBondContact O-CG1 3.49Å; I667-I671 PolarHBondContact O-N 3.22Å
668L80.6Confident72.2Confident105 Ų105113.1 Ų113.155%0.5560%0.602SS.*Hα-helixtrans-61.9-41.8176.3-92155000112.5L664 V665 I671 C672L664-L668 WeakPolarHBondContact O-CB 3.25Å; L664-L668 PolarHBondContact O-N 3.05Å; V665-L668 PolarHBondContact O-N 2.96Å; L668-I671 PolarHBondContact O-N 3.32Å; L668-C672 WeakPolarHBondContact O-CB 3.36Å; L668-C672 PolarHBondContact O-N 2.86Å; L668-C672 PolarHBondContact O-SG 2.99Å
669L75.6Confident69.5Low102 Ų102113.1 Ų113.153%0.53461%0.61SS.*Hα-helixtrans-65.4-40.3175.5-75.2170.8000111.8V665 G666 I667 I671 C672 C673V665-L669 HydrophobicContact CG1-CD1 4.01Å; V665-L669 HydrophobicContact CG1-CG 4.35Å; V665-L669 WeakPolarHBondContact O-CB 3.45Å; V665-L669 WeakPolarHBondContact O-CG 3.3Å; V665-L669 PolarHBondContact O-N 3.35Å; G666-L669 PolarHBondContact O-N 3.36Å; I667-L669 PolarHBondContact O-N 2.98Å; L669-I671 VanDerWaalsContact C-N 3.32Å; L669-I671 PolarHBondContact O-N 3.48Å; L669-C672 PolarHBondContact O-N 3.48Å; L669-C673 VanDerWaalsContact O-CB 3.23Å; L669-C673 WeakPolarHBondContact O-CB 3.45Å; L669-C673 PolarHBondContact O-N 2.96Å
670L69.6Low67Low132 Ų132116.7 Ų116.769%0.69162%0.624SS**Hα-helixtrans-62.3-39.7173.9-77.2165.8000111.7G666 I667 G674G666-L670 WeakPolarHBondContact O-CG 3.46Å; G666-L670 PolarHBondContact O-N 3.29Å; I667-L670 PolarHBondContact O-N 2.87Å; L670-G674 WeakPolarHBondContact O-CA 3.37Å; L670-G674 PolarHBondContact O-N 2.95Å
671I74.7Confident64.1Low111 Ų111123.9 Ų123.957%0.56964%0.643SS**Hα-helixtrans-68.5-41.8176.2-66.2165.4000111.1I667 L668 L669I667-I671 HydrophobicContact CG2-CD1 3.79Å; I667-I671 VanDerWaalsContact O-CG1 3.25Å; I667-I671 WeakPolarHBondContact O-CG1 3.49Å; I667-I671 PolarHBondContact O-N 3.22Å; L668-I671 PolarHBondContact O-N 3.32Å; L669-I671 VanDerWaalsContact C-N 3.32Å; L669-I671 PolarHBondContact O-N 3.48Å
672C67.8Low61.2Low91 Ų91130.3 Ų130.362%0.61566%0.661SS**Hα-helixtrans-72.1-41.1-180-72.90000112.7L668 L669L668-C672 WeakPolarHBondContact O-CB 3.36Å; L668-C672 PolarHBondContact O-N 2.86Å; L668-C672 PolarHBondContact O-SG 2.99Å; L669-C672 PolarHBondContact O-N 3.48Å
673C55.7Low58.5Low90 Ų90128.5 Ų128.561%0.60866%0.662SS**Hα-helixtrans-79.7-21.9177.7-69.10000112.7L669 K675 S676L669-C673 VanDerWaalsContact O-CB 3.23Å; L669-C673 WeakPolarHBondContact O-CB 3.45Å; L669-C673 PolarHBondContact O-N 2.96Å; C673-K675 PolarHBondContact O-N 3.29Å; C673-S676 PolarHBondContact O-N 2.96Å; C673-S676 VanDerWaalsContact O-N 3.13Å
674G47.4Very low55.8Low65 Ų65132.8 Ų132.867%0.6768%0.676SS**THydrogen-bonded Turntrans-63.9-6.8178.400000115.3L670L670-G674 WeakPolarHBondContact O-CA 3.37Å; L670-G674 PolarHBondContact O-N 2.95Å
675K42.4Very low52.9Low196 Ų196133.3 Ų133.385%0.85269%0.686SS**THydrogen-bonded Turntrans-92.31173.8-72-169.3176.1-179.30114.7C673 K677C673-K675 PolarHBondContact O-N 3.29Å; K675-K677 PolarHBondContact O-N 3.48Å
676S40.2Very low50.1Low99 Ų99139 Ų13969%0.69271%0.71SS**SBendtrans-90.796.3179.3-170.70000112.5C673C673-S676 PolarHBondContact O-N 2.96Å; C673-S676 VanDerWaalsContact O-N 3.13Å
677K38.6Very low47.5Very low196 Ų196148 Ų14885%0.85274%0.737SS**  trans38.686.2154.7-69.4-178.9176.7177.10117.1K675 S679K675-K677 PolarHBondContact O-N 3.48Å; K677-S679 PolarHBondContact O-N 3.28Å
678Y34.7Very low45Very low238 Ų238152.2 Ų152.293%0.93375%0.754SS**  trans-67.992.1158.7-125.3-98.1000109.7
679S34.4Very low42.8Very low101 Ų101152.2 Ų152.271%0.70676%0.76SS**  trans-85115.5168.3167.10000108.7K677 R681K677-S679 PolarHBondContact O-N 3.28Å; S679-R681 PolarHBondContact O-N 2.93Å
680Q35.2Very low40.7Very low188 Ų188155.9 Ų155.988%0.87978%0.78SS**  trans-59.999.6176.2-77.1-179.4-25.900111.1
681R31.8Very low39Very low226 Ų226156.2 Ų156.285%0.85379%0.788SS**  trans-107.1100.6156.8-95.4-176.9172.4175.9-1.9108.9S679 V683S679-R681 PolarHBondContact O-N 2.93Å; R681-V683 PolarHBondContact O-N 3.4Å
682R29.8Very low37Very low251 Ų251153.8 Ų153.895%0.94779%0.79SS**  trans-59.693.9165.1-82.8178.5170.4172.6-3.1108.6
683V34.3Very low35.3Very low116 Ų116159.2 Ų159.270%0.70380%0.803SS**  trans-87.4109.5164.2-179.20000106.9R681 C685R681-V683 PolarHBondContact O-N 3.4Å; V683-C685 VanDerWaalsContact C-N 3.32Å; V683-C685 PolarHBondContact O-N 2.84Å
684K30.5Very low34.3Very low203 Ų203161.5 Ų161.588%0.88381%0.809SS**  trans-76.581.8178.7-143.2-177.3-171.8-174.70107.4M686K684-M686 PolarHBondContact O-N 2.89Å
685C30.7Very low33.7Very low103 Ų103166.3 Ų166.370%0.69682%0.82SS**  trans-74.4108.4172.5-77.60000108.8V683 Y687V683-C685 VanDerWaalsContact C-N 3.32Å; V683-C685 PolarHBondContact O-N 2.84Å; C685-Y687 PolarHBondContact O-N 2.97Å
686M30.2Very low33.3Very low188 Ų188163.9 Ų163.993%0.92681%0.814SS**  trans-63.2112.7165.3-65.6-171.7-164.200107.8K684K684-M686 PolarHBondContact O-N 2.89Å
687Y29.4Very low33Very low221 Ų221168.4 Ų168.487%0.86782%0.822SS**  trans-92.6103.5169.3-124.6-92.8000106.9C685C685-Y687 PolarHBondContact O-N 2.97Å
688E30.6Very low32.5Very low175 Ų175164.2 Ų164.282%0.81882%0.817SS**  trans-76.3121.9165.1-120.2172.7-179.200107.7L690E688-L690 PolarHBondContact O-N 3.43Å
689P34.3Very low32.3Very low104 Ų104159 Ų15968%0.67581%0.81SS**  trans-71.7114-178.826.4-29.9000109.6T691P689-T691 VanDerWaalsContact C-N 3.34Å; P689-T691 PolarHBondContact O-N 3Å
690L32.9Very low32Very low179 Ų179158.7 Ų158.794%0.93781%0.805SS**  trans-63.595.4168.5-78.3163.6000109E688 G692E688-L690 PolarHBondContact O-N 3.43Å; L690-G692 PolarHBondContact O-N 3.33Å
691T33.2Very low31.7Very low140 Ų140156.3 Ų156.386%0.85980%0.804SS**  trans-77.167.417143.90000109.4P689P689-T691 VanDerWaalsContact C-N 3.34Å; P689-T691 PolarHBondContact O-N 3Å
692G32.1Very low31.4Very low60 Ų60154.9 Ų154.962%0.61980%0.8SS**  trans-104.695.8173.800000110.7L690 N694L690-G692 PolarHBondContact O-N 3.33Å; G692-N694 PolarHBondContact O-N 2.85Å
693K32.1Very low31.3Very low204 Ų204150.9 Ų150.989%0.88779%0.792SS**  trans-57.3101.1159.6-82178.7172.1179.50108
694N35.9Very low30.9Very low138 Ų138152 Ų15274%0.73880%0.799SS**  trans-129.7103.4164.5-91.2-17.2000108G692 I696G692-N694 PolarHBondContact O-N 2.85Å; N694-I696 HydrophobicContact CB-CG1 4.41Å; N694-I696 PolarHBondContact O-N 3.47Å
695D34.2Very low30.7Very low167 Ų167154.6 Ų154.689%0.89381%0.811SS**  trans-62.178168.4-70.2-47.9000109.8K697D695-K697 PolarHBondContact O-N 3.29Å
696I34.6Very low30.7Very low144 Ų144157.2 Ų157.274%0.73882%0.816SS**  trans-9190.7167.5-58.2177.1000106.2N694 S698N694-I696 HydrophobicContact CB-CG1 4.41Å; N694-I696 PolarHBondContact O-N 3.47Å; I696-S698 PolarHBondContact O-N 2.88Å
697K32.7Very low30.7Very low194 Ų194155.5 Ų155.584%0.84381%0.811SS**  trans-51.5111.1162.7-78.9-176.9175.4-177.80107.6D695 V699D695-K697 PolarHBondContact O-N 3.29Å; K697-V699 PolarHBondContact O-N 3.04Å; K697-V699 VanDerWaalsContact O-N 3.1Å
698S29.2Very low30.8Very low108 Ų108151.9 Ų151.976%0.75581%0.808SS**  trans-58.3110.1172.851.20000109.1I696 P700I696-S698 PolarHBondContact O-N 2.88Å; S698-P700 WeakPolarHBondContact O-CD 3.35Å
699V29.8Very low30.8Very low130 Ų130150.5 Ų150.579%0.78881%0.807SS**  trans-75.9115.8167.31790000106.8K697 T701K697-V699 PolarHBondContact O-N 3.04Å; K697-V699 VanDerWaalsContact O-N 3.1Å; V699-T701 PolarHBondContact O-N 3.13Å
700P29.1Very low30.6Very low93 Ų93153.4 Ų153.460%0.60482%0.815SS**  trans-67.8120.5178.9-14.429.2000109.6S698 Y702S698-P700 WeakPolarHBondContact O-CD 3.35Å; P700-Y702 WeakPolarHBondContact O-CD2 3.23Å; P700-Y702 PolarHBondContact O-N 2.98Å
701T27.7Very low30.4Very low139 Ų139151.7 Ų151.785%0.85381%0.807SS**  trans-69.1107.2169.727.40000109.3V699 Q703V699-T701 PolarHBondContact O-N 3.13Å; T701-Q703 PolarHBondContact O-N 2.78Å; T701-Q703 VanDerWaalsContact O-N 3.1Å
702Y26.7Very low30.2Very low196 Ų196152.6 Ų152.677%0.76980%0.803SS**  trans-62.7107.7172.9-68.9-89.5000109.8P700 T704P700-Y702 WeakPolarHBondContact O-CD2 3.23Å; P700-Y702 PolarHBondContact O-N 2.98Å; Y702-T704 PolarHBondContact O-N 3.29Å
703Q26.9Very low30Very low166 Ų166159.7 Ų159.778%0.77682%0.818SS**  trans-72.5106.1160-79.7-176.3-30.100107.2T701 F705T701-Q703 PolarHBondContact O-N 2.78Å; T701-Q703 VanDerWaalsContact O-N 3.1Å; Q703-F705 PolarHBondContact O-N 3.35Å; Q703-F705 VanDerWaalsContact O-N 3.15Å
704T26.6Very low29.9Very low139 Ų139156 Ų15685%0.85381%0.812SS**  trans-58.4112.3165.940.60000108.5Y702Y702-T704 PolarHBondContact O-N 3.29Å
705F25.1Very low29.3Very low258 Ų258157.6 Ų157.6100%1.13282%0.818SS**  trans-82.50169.8-95.3-83.4000111.2Q703Q703-F705 PolarHBondContact O-N 3.35Å; Q703-F705 VanDerWaalsContact O-N 3.15Å

Retrieved 705 of 705 residues in 534.7 ms (Link to these results)