A0A077Z3E5_TRITR Loading...

Uncharacterized protein

AlphaFold DB , UniProt , Accession A0A077Z3E5, Species TRITR (Trichuris trichiura, Whipworm), Gene n/a, Length 256 aa.

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Site Residue pLDDT pLDDT confidence pLDDT10 pLDDT10 confidence SASA SASA [Ų] SASA10 SASA10 [Ų] RSA RSA unformatted RSA10 RSA10 unformatted Surface Surface10 (not used) Disorder (not used) Disorder Sec. str. Secondary structure Isomer Phi (φ) Psi (ψ) Omega (ω) Chi 1 (χ1) Chi 2 (χ2) Chi 3 (χ3) Chi 4 (χ4) Chi 5 (χ5) Tau (τ) Contacts (colored by PAE) Contact details
1M82.7Confident84.6Confident130 Ų13069.5 Ų69.564%0.6439%0.385SS*.  0143.60-175167.865.200108.6N26M1-N26 PolarHBondContact O-N 2.92Å
2V90.1Very high83.5Confident84 Ų8479.7 Ų79.751%0.50943%0.428SS..EExtended strand (participates in β ladder)trans-98.9125.8173174.90000108.2C23 Y24 L71V2-C23 HydrophobicContact CG1-CB 4.48Å; V2-Y24 WeakPolarHBondContact CA-O 3.37Å; V2-L71 HydrophobicContact CB-CD1 4.39Å; V2-L71 HydrophobicContact CG1-CD1 3.75Å; V2-L71 HydrophobicContact CG2-CD1 3.73Å
3D90Very high82.6Confident38 Ų3888.9 Ų88.920%0.20346%0.455CS..EExtended strand (participates in β ladder)trans-104.9136.7173.6-71.6-9.2000108.8C23 Y24 N26D3-C23 WeakPolarHBondContact O-CA 3.24Å; D3-Y24 HydrophobicContact CB-CD2 4.44Å; D3-Y24 HydrophobicContact CB-CE1 4.11Å; D3-Y24 HydrophobicContact CB-CE2 3.84Å; D3-Y24 PolarHBondContact N-O 3.25Å; D3-Y24 PolarHBondContact O-N 2.57Å; D3-N26 WeakPolarHBondContact OD2-CB 3.44Å; D3-N26 PolarHBondContact OD2-ND2 3.2Å
4C89.9Confident81.6Confident60 Ų6086.7 Ų86.741%0.40547%0.465SS..EExtended strand (participates in β ladder)trans-132.7146177.9-650000112.8F6 L22 C23C4-F6 HydrophobicContact CB-CD2 4.05Å; C4-F6 HydrophobicContact CB-CE2 3.25Å; C4-F6 HydrophobicContact CB-CZ 3.66Å; C4-L22 CarbonylContact C-O 3.41Å; C4-L22 WeakPolarHBondContact CA-O 3.2Å; C4-C23 HydrophobicContact CB-CB 4.2Å; C4-C23 WeakPolarHBondContact CB-SG 3.32Å; C4-C23 WeakPolarHBondContact SG-CB 3.22Å; C4-C23 CovalentContact SG-SG 2.05Å; C4-C23 PolarHBondContact SG-SG 3.32Å
5Q89.7Confident80.8Confident25 Ų2585.9 Ų85.912%0.11747%0.469CS..EExtended strand (participates in β ladder)trans-120.8132.1169.3-59.2179.818.700108.2A21 L22 W47 L57 Q58Q5-A21 CarbonylContact O-C 3.58Å; Q5-A21 WeakPolarHBondContact O-CA 3.06Å; Q5-L22 HydrophobicContact CB-CB 4.32Å; Q5-L22 PolarHBondContact N-O 2.95Å; Q5-L22 PolarHBondContact O-N 3.07Å; Q5-W47 HydrophobicContact CB-CH2 3.94Å; Q5-W47 HydrophobicContact CB-CZ3 3.83Å; Q5-W47 HydrophobicContact CG-CH2 3.65Å; Q5-W47 HydrophobicContact CG-CZ3 4.06Å; Q5-L57 HydrophobicContact CB-CD2 4.07Å; Q5-Q58 PolarHBondContact NE2-O 2.89Å; Q5-Q58 VanDerWaalsContact OE1-N 3.13Å
6F87.7Confident80.4Confident114 Ų11483.7 Ų83.750%0.547%0.472SS..EExtended strand (participates in β ladder)trans-132.2138.3178.6-61.3-81.2000110.1C4 A21 C23 W72C4-F6 HydrophobicContact CB-CD2 4.05Å; C4-F6 HydrophobicContact CB-CE2 3.25Å; C4-F6 HydrophobicContact CB-CZ 3.66Å; F6-A21 HydrophobicContact CD1-CB 3.8Å; F6-A21 HydrophobicContact CE1-CB 3.95Å; F6-C23 VanDerWaalsContact CZ-SG 3.59Å; F6-W72 HydrophobicContact CE1-CE3 4.18Å; F6-W72 AromaticContact CE1-CZ3 3.94Å; F6-W72 HydrophobicContact CE1-CZ3 3.94Å
7A87.5Confident80.3Confident21 Ų2184.2 Ų84.217%0.17447%0.465CS..EExtended strand (participates in β ladder)trans-129.1131.9165.700000108L19 A20 P55A7-L19 PolarHBondContact O-N 3.08Å; A7-A20 HydrophobicContact CB-CB 4.41Å; A7-A20 PolarHBondContact N-O 3.03Å; A7-A20 PolarHBondContact O-N 3.25Å; A7-A20 VanDerWaalsContact O-N 3.11Å; A7-P55 HydrophobicContact CB-CB 3.5Å; A7-P55 VanDerWaalsContact CB-CB 3.5Å; A7-P55 HydrophobicContact CB-CG 3.52Å
8A84.1Confident80.6Confident54 Ų5482.4 Ų82.445%0.44646%0.456SS..EExtended strand (participates in β ladder)trans-137.2147.5-177.300000110.7R17A8-R17 CarbonylContact C-O 3.47Å; A8-R17 WeakPolarHBondContact CA-O 3.04Å; A8-R17 WeakPolarHBondContact CB-O 3.32Å
9E80.4Confident81Confident60 Ų6079.4 Ų79.428%0.2844%0.44SS..EExtended strand (participates in β ladder)trans-84.8112.9167.8-178.8179-163.500107.5G16 R17 L19 S88E9-G16 CarbonylContact O-C 3.55Å; E9-G16 VanDerWaalsContact O-CA 3.25Å; E9-G16 WeakPolarHBondContact O-CA 3.36Å; E9-R17 PolarHBondContact N-O 2.04Å; E9-R17 PolarHBondContact O-N 3.25Å; E9-L19 HydrophobicContact CB-CD1 4.06Å; E9-L19 HydrophobicContact CB-CD2 3.97Å; E9-L19 HydrophobicContact CB-CG 4.03Å; E9-S88 PolarHBondContact OE2-OG 2.86Å
10I76.5Confident81.5Confident133 Ų13375.5 Ų75.568%0.68242%0.418SS*.EExtended strand (participates in β ladder)trans-93118.9177.1-57.3175.6000108.1
11T72.4Confident82.1Confident45 Ų4571.9 Ų71.928%0.27640%0.398SS..  trans-79.5163.817472.80000111Y13 G14 S15T11-Y13 PolarHBondContact O-N 2.68Å; T11-G14 PolarHBondContact O-N 3.14Å; T11-S15 WeakPolarHBondContact CG2-O 3.42Å; T11-S15 PolarHBondContact N-O 3.19Å; T11-S15 PolarHBondContact OG1-O 3.1Å; T11-S15 PolarHBondContact OG1-OG 3.2Å
12Q70.6Confident82.6Confident192 Ų19265.7 Ų65.790%0.89737%0.367SS*.THydrogen-bonded Turntrans-55.1-25177.6-69.3-179.5-20.200113.7G14Q12-G14 VanDerWaalsContact C-N 3.31Å
13Y72.4Confident82.9Confident200 Ų20062.2 Ų62.278%0.78435%0.346SS*.THydrogen-bonded Turntrans-89.17.1-179.7-57.6-73.3000113.6T11 S15T11-Y13 PolarHBondContact O-N 2.68Å; Y13-S15 PolarHBondContact O-N 3.15Å
14G68.7Low83Confident58 Ų5861.3 Ų61.360%0.59834%0.34SS*.SBendtrans78.2-6.1179.900000114.7T11 Q12 G16T11-G14 PolarHBondContact O-N 3.14Å; Q12-G14 VanDerWaalsContact C-N 3.31Å; G14-G16 PolarHBondContact O-N 3.02Å
15S69.5Low83Confident75 Ų7564.5 Ų64.552%0.52435%0.35SS..PPolyproline II helixtrans-70.5120.9168.258.60000109.2T11 Y13T11-S15 WeakPolarHBondContact CG2-O 3.42Å; T11-S15 PolarHBondContact N-O 3.19Å; T11-S15 PolarHBondContact OG1-O 3.1Å; T11-S15 PolarHBondContact OG1-OG 3.2Å; Y13-S15 PolarHBondContact O-N 3.15Å
16G74.8Confident82.6Confident50 Ų5064.7 Ų64.752%0.51535%0.351SS..EExtended strand (participates in β ladder)trans-102.4131.9177.800000111E9 G14E9-G16 CarbonylContact O-C 3.55Å; E9-G16 VanDerWaalsContact O-CA 3.25Å; E9-G16 WeakPolarHBondContact O-CA 3.36Å; G14-G16 PolarHBondContact O-N 3.02Å
17R79Confident82Confident92 Ų9263.6 Ų63.635%0.34736%0.355SS..EExtended strand (participates in β ladder)trans-100.5126.4167.7179.8-179.4173.7170.79.4109.4A8 E9 L19 S88A8-R17 CarbonylContact C-O 3.47Å; A8-R17 WeakPolarHBondContact CA-O 3.04Å; A8-R17 WeakPolarHBondContact CB-O 3.32Å; E9-R17 PolarHBondContact N-O 2.04Å; E9-R17 PolarHBondContact O-N 3.25Å; R17-L19 PolarHBondContact O-N 3.43Å; R17-S88 VanDerWaalsContact CD-OG 3.3Å; R17-S88 WeakPolarHBondContact CD-OG 3.37Å; R17-S88 PolarHBondContact NH1-O 3.42Å; R17-S88 PolarHBondContact NH1-OG 3.36Å
18V84.4Confident81Confident52 Ų5267.2 Ų67.232%0.31537%0.371SS..EExtended strand (participates in β ladder)trans-64.1125.9172.9179.70000109.1A21V18-A21 HydrophobicContact CG1-CB 3.96Å
19L88.4Confident79.5Confident26 Ų2670 Ų7014%0.13638%0.382CS..EExtended strand (participates in β ladder)trans-97.7-36.3174.6-62.1-174.1000111.6A7 E9 R17 P55 T75 A76 F81A7-L19 PolarHBondContact O-N 3.08Å; E9-L19 HydrophobicContact CB-CD1 4.06Å; E9-L19 HydrophobicContact CB-CD2 3.97Å; E9-L19 HydrophobicContact CB-CG 4.03Å; R17-L19 PolarHBondContact O-N 3.43Å; L19-P55 HydrophobicContact CB-CG 4.08Å; L19-P55 HydrophobicContact CD1-CG 4.45Å; L19-T75 CarbonylContact O-C 3.46Å; L19-A76 WeakPolarHBondContact O-CA 3.12Å; L19-A76 PolarHBondContact O-N 2.89Å; L19-A76 VanDerWaalsContact O-N 3.15Å; L19-F81 HydrophobicContact CD1-CZ 3.87Å; L19-F81 HydrophobicContact CD2-CE1 4.43Å; L19-F81 HydrophobicContact CD2-CE2 4.43Å; L19-F81 HydrophobicContact CD2-CZ 3.6Å; L19-F81 HydrophobicContact CG-CZ 4.3Å
20A91.4Very high78Confident0 Ų073.9 Ų73.90%041%0.405CS..EExtended strand (participates in β ladder)trans-151.5141.3176.100000110.1A7 P55 L57 E74A7-A20 HydrophobicContact CB-CB 4.41Å; A7-A20 PolarHBondContact N-O 3.03Å; A7-A20 PolarHBondContact O-N 3.25Å; A7-A20 VanDerWaalsContact O-N 3.11Å; A20-P55 HydrophobicContact CB-CG 4.15Å; A20-L57 HydrophobicContact CB-CD1 4.07Å; A20-L57 HydrophobicContact CB-CD2 3.95Å; A20-L57 HydrophobicContact CB-CG 3.89Å; A20-E74 CarbonylContact C-O 3.59Å; A20-E74 WeakPolarHBondContact CA-O 3.04Å
21A93.5Very high76.6Confident0 Ų071.9 Ų71.90%040%0.399CS..EExtended strand (participates in β ladder)trans-141135.8176.600000110.4Q5 F6 V18 W72 Y73 E74Q5-A21 CarbonylContact O-C 3.58Å; Q5-A21 WeakPolarHBondContact O-CA 3.06Å; F6-A21 HydrophobicContact CD1-CB 3.8Å; F6-A21 HydrophobicContact CE1-CB 3.95Å; V18-A21 HydrophobicContact CG1-CB 3.96Å; A21-W72 HydrophobicContact CB-CD2 3.93Å; A21-W72 HydrophobicContact CB-CE3 4.36Å; A21-W72 HydrophobicContact CB-CG 4.3Å; A21-W72 HydrophobicContact CB-CZ2 4.12Å; A21-Y73 CarbonylContact O-C 3.57Å; A21-Y73 WeakPolarHBondContact O-CA 3.31Å; A21-E74 HydrophobicContact CB-CB 4.43Å; A21-E74 PolarHBondContact N-O 2.85Å; A21-E74 PolarHBondContact O-N 3.17Å; A21-E74 VanDerWaalsContact O-O 3.13Å
22L94.4Very high75.2Confident0 Ų082.3 Ų82.30%043%0.434CS..EExtended strand (participates in β ladder)trans-133.7120.1171.3167.865.8000107.5C4 Q5 Y24 L57 L59 L70 W72 Y73C4-L22 CarbonylContact C-O 3.41Å; C4-L22 WeakPolarHBondContact CA-O 3.2Å; Q5-L22 HydrophobicContact CB-CB 4.32Å; Q5-L22 PolarHBondContact N-O 2.95Å; Q5-L22 PolarHBondContact O-N 3.07Å; L22-Y24 HydrophobicContact CD1-CD1 4.05Å; L22-Y24 HydrophobicContact CD2-CD1 4.18Å; L22-Y24 HydrophobicContact CD2-CE1 4.04Å; L22-Y24 HydrophobicContact CG-CD1 3.85Å; L22-Y24 HydrophobicContact CG-CE1 4.14Å; L22-L57 HydrophobicContact CB-CD1 3.91Å; L22-L57 HydrophobicContact CB-CD2 4.05Å; L22-L57 HydrophobicContact CB-CG 4.43Å; L22-L59 HydrophobicContact CD2-CG 4.17Å; L22-L70 HydrophobicContact CD1-CD1 3.96Å; L22-L70 HydrophobicContact CD1-CD2 3.85Å; L22-L70 HydrophobicContact CD1-CG 4.46Å; L22-W72 CarbonylContact C-O 3.54Å; L22-W72 WeakPolarHBondContact CA-O 3.33Å; L22-Y73 HydrophobicContact CD1-CD2 4Å
23C95.3Very high73.9Confident11 Ų1181.4 Ų81.47%0.07443%0.427CS..EExtended strand (participates in β ladder)trans-127.4135.8170-71.40000110V2 D3 C4 F6 L71 W72V2-C23 HydrophobicContact CG1-CB 4.48Å; D3-C23 WeakPolarHBondContact O-CA 3.24Å; C4-C23 HydrophobicContact CB-CB 4.2Å; C4-C23 WeakPolarHBondContact CB-SG 3.32Å; C4-C23 WeakPolarHBondContact SG-CB 3.22Å; C4-C23 CovalentContact SG-SG 2.05Å; C4-C23 PolarHBondContact SG-SG 3.32Å; F6-C23 VanDerWaalsContact CZ-SG 3.59Å; C23-L71 HydrophobicContact CB-CB 4.13Å; C23-L71 WeakPolarHBondContact O-CA 3.49Å; C23-L71 WeakPolarHBondContact O-CB 3.35Å; C23-L71 PolarHBondContact O-N 3.15Å; C23-W72 HydrophobicContact CB-CB 3.98Å; C23-W72 PolarHBondContact N-O 2.79Å; C23-W72 PolarHBondContact O-N 2.93Å; C23-W72 VanDerWaalsContact O-N 3.14Å
24Y92.8Very high72.5Confident19 Ų1976.3 Ų76.38%0.07542%0.421CS..EExtended strand (participates in β ladder)trans-150.7157.4-179.960.1-88.8000111.7V2 D3 L22 N26 Y62 L63V2-Y24 WeakPolarHBondContact CA-O 3.37Å; D3-Y24 HydrophobicContact CB-CD2 4.44Å; D3-Y24 HydrophobicContact CB-CE1 4.11Å; D3-Y24 HydrophobicContact CB-CE2 3.84Å; D3-Y24 PolarHBondContact N-O 3.25Å; D3-Y24 PolarHBondContact O-N 2.57Å; L22-Y24 HydrophobicContact CD1-CD1 4.05Å; L22-Y24 HydrophobicContact CD2-CD1 4.18Å; L22-Y24 HydrophobicContact CD2-CE1 4.04Å; L22-Y24 HydrophobicContact CG-CD1 3.85Å; L22-Y24 HydrophobicContact CG-CE1 4.14Å; Y24-N26 HydrophobicContact CE2-CB 4.18Å; Y24-N26 PolarHBondContact O-N 2.75Å; Y24-Y62 WeakPolarHBondContact CD2-OH 3.16Å; Y24-Y62 VanDerWaalsContact CE2-OH 3.29Å; Y24-Y62 WeakPolarHBondContact CE2-OH 3.1Å; Y24-L63 HydrophobicContact CD1-CD1 3.26Å; Y24-L63 HydrophobicContact CD2-CD1 3.55Å; Y24-L63 HydrophobicContact CD2-CD2 4.45Å; Y24-L63 HydrophobicContact CE1-CD1 3.55Å; Y24-L63 HydrophobicContact CE2-CD1 3.83Å; Y24-L63 HydrophobicContact CG-CD1 3.26Å; Y24-L63 HydrophobicContact CG-CD2 4.38Å; Y24-L63 HydrophobicContact CG-CG 4.44Å
25Q90.3Very high71.3Confident128 Ų12884.9 Ų84.960%0.59844%0.435SS*.EExtended strand (participates in β ladder)trans-79.4118.9171.1-170.7163.4-2.500109P27Q25-P27 WeakPolarHBondContact O-CD 3.35Å
26N81.5Confident70.1Confident28 Ų2888.1 Ų88.115%0.1544%0.442CS..  trans-82.2116.3175.8-172.9-10000109M1 D3 Y24 I28M1-N26 PolarHBondContact O-N 2.92Å; D3-N26 WeakPolarHBondContact OD2-CB 3.44Å; D3-N26 PolarHBondContact OD2-ND2 3.2Å; Y24-N26 HydrophobicContact CE2-CB 4.18Å; Y24-N26 PolarHBondContact O-N 2.75Å; N26-I28 VanDerWaalsContact C-N 3.29Å; N26-I28 WeakPolarHBondContact OD1-CB 3.27Å; N26-I28 PolarHBondContact OD1-N 3.45Å; N26-I28 PolarHBondContact OD1-O 3.29Å
27P74.2Confident68.6Low91 Ų9195 Ų9559%0.59146%0.461SS*.SBendtrans-76-20.3179.331.7-34.5000112.2Q25 T29Q25-P27 WeakPolarHBondContact O-CD 3.35Å; P27-T29 PolarHBondContact O-N 3.31Å; P27-T29 VanDerWaalsContact O-N 3.09Å
28I66.3Low67Low97 Ų9793.9 Ų93.950%0.49746%0.461SS..  trans-82.890.2177.8-54.1170.8000106.5N26 D30 T31N26-I28 VanDerWaalsContact C-N 3.29Å; N26-I28 WeakPolarHBondContact OD1-CB 3.27Å; N26-I28 PolarHBondContact OD1-N 3.45Å; N26-I28 PolarHBondContact OD1-O 3.29Å; I28-D30 PolarHBondContact O-N 2.94Å; I28-T31 WeakPolarHBondContact CG2-OG1 3.39Å
29T53.8Low65Low112 Ų112101.3 Ų101.369%0.68748%0.483SS*.  trans-69.1-16.6175.439.90000112.9P27P27-T29 PolarHBondContact O-N 3.31Å; P27-T29 VanDerWaalsContact O-N 3.09Å
30D48.5Very low63.1Low143 Ų143102.5 Ų102.577%0.76550%0.502SS*.  trans-136.729.9-149.8-127.14.2000117I28I28-D30 PolarHBondContact O-N 2.94Å
31T45.8Very low61.1Low91 Ų91105.2 Ų105.256%0.55853%0.53SS*.  trans-119.5111.916143.20000109.2I28 K33I28-T31 WeakPolarHBondContact CG2-OG1 3.39Å; T31-K33 PolarHBondContact O-N 3.26Å
32W43.3Very low59.1Low263 Ų263110.5 Ų110.5100%0.99655%0.554SS**  trans-5469.3151.2-78.8-63.3000109S34W32-S34 PolarHBondContact O-N 3.38Å
33K44.4Very low57Low174 Ų174113.4 Ų113.476%0.75757%0.569SS**  trans-65.2105.3151.8-77.7-169.7175.9-178.20103.4T31 R35T31-K33 PolarHBondContact O-N 3.26Å; K33-R35 PolarHBondContact O-N 3.11Å
34S41.7Very low55.3Low93 Ų93117.3 Ų117.365%0.6560%0.595SS**  trans-31114.3161.245.60000106.5W32 E36W32-S34 PolarHBondContact O-N 3.38Å; S34-E36 PolarHBondContact O-N 2.95Å
35R45Very low53.8Low238 Ų238125 Ų12590%0.89863%0.629SS**  trans-62.883.3157.1-74.3-177.3-177.9-160.80.7103.1K33 Q37K33-R35 PolarHBondContact O-N 3.11Å; R35-Q37 PolarHBondContact O-N 3.12Å
36E44.4Very low52.8Low143 Ų143124.5 Ų124.567%0.66863%0.625SS**  trans-46.6123.2160.9-81-178164.600103.8S34 I38S34-E36 PolarHBondContact O-N 2.95Å; E36-I38 HydrophobicContact CB-CD1 4.3Å; E36-I38 HydrophobicContact CB-CG1 3.74Å; E36-I38 WeakPolarHBondContact O-CG1 3.06Å; E36-I38 PolarHBondContact O-N 2.92Å
37Q42.3Very low52.8Low195 Ų195125.7 Ų125.791%0.91163%0.627SS**  trans-72.266.9179-153.8177.32300105.9R35 R39R35-Q37 PolarHBondContact O-N 3.12Å; Q37-R39 PolarHBondContact O-N 2.92Å; Q37-R39 VanDerWaalsContact O-N 3.16Å
38I45Very low53.5Low68 Ų68122.5 Ų122.535%0.34961%0.608SS.*  trans-67.4117.9-176.4-59.4171.3000105E36 G40 E42 M43E36-I38 HydrophobicContact CB-CD1 4.3Å; E36-I38 HydrophobicContact CB-CG1 3.74Å; E36-I38 WeakPolarHBondContact O-CG1 3.06Å; E36-I38 PolarHBondContact O-N 2.92Å; I38-G40 PolarHBondContact O-N 2.76Å; I38-E42 HydrophobicContact CG2-CB 4.17Å; I38-M43 HydrophobicContact CB-CG 4.24Å; I38-M43 HydrophobicContact CB-SD 4.27Å; I38-M43 HydrophobicContact CD1-SD 4.38Å; I38-M43 HydrophobicContact CG2-CG 3.78Å; I38-M43 HydrophobicContact CG2-SD 4.11Å
39R43.4Very low54.8Low208 Ų208117.9 Ų117.979%0.78558%0.584SS**  trans-54.3129.1179.7-69.5-176.9-178.2-173.41.2108.8Q37 G41 E42Q37-R39 PolarHBondContact O-N 2.92Å; Q37-R39 VanDerWaalsContact O-N 3.16Å; R39-G41 PolarHBondContact O-N 2.91Å; R39-E42 PolarHBondContact O-N 3.36Å
40G48.5Very low56.5Low51 Ų51114.2 Ų114.253%0.52656%0.563SS.*Hα-helixtrans-50.8-32.8-173.600000114.6I38 E42 M43 C44I38-G40 PolarHBondContact O-N 2.76Å; G40-E42 VanDerWaalsContact C-N 3.35Å; G40-E42 PolarHBondContact O-N 3.03Å; G40-M43 WeakPolarHBondContact O-CB 3.33Å; G40-M43 PolarHBondContact O-N 2.78Å; G40-C44 PolarHBondContact O-N 3.48Å; G40-C44 PolarHBondContact O-SG 2.99Å; G40-C44 VanDerWaalsContact O-SG 3.4Å
41G48.5Very low58.4Low57 Ų57110.9 Ų110.959%0.58856%0.562SS**Hα-helixtrans-64.6-30.5176.600000115.1R39R39-G41 PolarHBondContact O-N 2.91Å
42E52.5Low60.4Low110 Ų110108.1 Ų108.151%0.51455%0.545SS..Hα-helixtrans-75.7-31.9174.4-70.5-171.7171.900112.1I38 R39 G40 K46I38-E42 HydrophobicContact CG2-CB 4.17Å; R39-E42 PolarHBondContact O-N 3.36Å; G40-E42 VanDerWaalsContact C-N 3.35Å; G40-E42 PolarHBondContact O-N 3.03Å; E42-K46 PolarHBondContact O-N 3.27Å
43M49.9Very low62.5Low62 Ų62104.8 Ų104.831%0.30554%0.54SS..Hα-helixtrans-61.7-48.5176.1-67.3-90.7-76.900110.3I38 G40 K45 K46 W47I38-M43 HydrophobicContact CB-CG 4.24Å; I38-M43 HydrophobicContact CB-SD 4.27Å; I38-M43 HydrophobicContact CD1-SD 4.38Å; I38-M43 HydrophobicContact CG2-CG 3.78Å; I38-M43 HydrophobicContact CG2-SD 4.11Å; G40-M43 WeakPolarHBondContact O-CB 3.33Å; G40-M43 PolarHBondContact O-N 2.78Å; M43-K45 VanDerWaalsContact C-N 3.32Å; M43-K45 PolarHBondContact O-N 3.15Å; M43-K46 PolarHBondContact O-N 2.79Å; M43-W47 HydrophobicContact CE-CH2 3.86Å; M43-W47 HydrophobicContact CE-CZ2 3.42Å; M43-W47 VanDerWaalsContact CE-CZ2 3.42Å; M43-W47 VanDerWaalsContact O-CB 3.25Å; M43-W47 WeakPolarHBondContact O-CB 3.25Å; M43-W47 VanDerWaalsContact O-CG 3.23Å; M43-W47 PolarHBondContact O-N 2.94Å; M43-W47 HydrophobicContact SD-CZ2 4.16Å
44C59.4Low64.6Low93 Ų9397.4 Ų97.463%0.62851%0.509SS*.Hα-helixtrans-57-42.9-178.4-62.10000112.7G40 W47 A48G40-C44 PolarHBondContact O-N 3.48Å; G40-C44 PolarHBondContact O-SG 2.99Å; G40-C44 VanDerWaalsContact O-SG 3.4Å; C44-W47 CarbonylContact O-C 3.51Å; C44-W47 PolarHBondContact O-N 3.02Å; C44-A48 PolarHBondContact O-N 3.05Å
45K61.5Low67Low180 Ų18093.9 Ų93.978%0.78348%0.484SS*.Hα-helixtrans-69.1-39.8179-69.9-174.9-179178.90112.8M43 W47 A48M43-K45 VanDerWaalsContact C-N 3.32Å; M43-K45 PolarHBondContact O-N 3.15Å; K45-W47 PolarHBondContact O-N 3.42Å; K45-A48 PolarHBondContact O-N 3.32Å
46K69Low69.3Low117 Ų11783.5 Ų83.551%0.50945%0.446SS..Hα-helixtrans-68.7-27.8177-74.9178.5-178.8170.10111.7E42 M43E42-K46 PolarHBondContact O-N 3.27Å; M43-K46 PolarHBondContact O-N 2.79Å
47W81.6Confident71.6Confident54 Ų5476.9 Ų76.921%0.20542%0.415CS..THydrogen-bonded Turntrans-99.118.3-177-6628.5000111.7Q5 M43 C44 K45 P55 Q56 Q58Q5-W47 HydrophobicContact CB-CH2 3.94Å; Q5-W47 HydrophobicContact CB-CZ3 3.83Å; Q5-W47 HydrophobicContact CG-CH2 3.65Å; Q5-W47 HydrophobicContact CG-CZ3 4.06Å; M43-W47 HydrophobicContact CE-CH2 3.86Å; M43-W47 HydrophobicContact CE-CZ2 3.42Å; M43-W47 VanDerWaalsContact CE-CZ2 3.42Å; M43-W47 VanDerWaalsContact O-CB 3.25Å; M43-W47 WeakPolarHBondContact O-CB 3.25Å; M43-W47 VanDerWaalsContact O-CG 3.23Å; M43-W47 PolarHBondContact O-N 2.94Å; M43-W47 HydrophobicContact SD-CZ2 4.16Å; C44-W47 CarbonylContact O-C 3.51Å; C44-W47 PolarHBondContact O-N 3.02Å; K45-W47 PolarHBondContact O-N 3.42Å; W47-P55 CarbonylContact O-C 3.58Å; W47-P55 WeakPolarHBondContact O-CA 3.45Å; W47-Q56 PolarHBondContact O-N 2.93Å; W47-Q58 HydrophobicContact CD2-CG 4.19Å; W47-Q58 HydrophobicContact CG-CG 3.94Å
48A89.7Confident73.9Confident23 Ų2371.5 Ų71.519%0.1939%0.39CS..BIsolated β-bridgetrans-98.1140.6177.500000111.1C44 K45 T52 L54C44-A48 PolarHBondContact O-N 3.05Å; K45-A48 PolarHBondContact O-N 3.32Å; A48-T52 WeakPolarHBondContact CB-O 3.32Å; A48-L54 CarbonylContact C-O 3.59Å; A48-L54 VanDerWaalsContact CA-O 3.32Å; A48-L54 WeakPolarHBondContact CA-O 3.49Å
49Y92.4Very high76.1Confident0 Ų069.1 Ų69.10%038%0.378CS..  trans-61.4136.1168.6-177-102.7000109.4G51 T52 L54 L78 F106 G110 K111 Q196 T198Y49-G51 PolarHBondContact O-N 3.39Å; Y49-T52 HydrophobicContact CD1-CG2 3.96Å; Y49-T52 PolarHBondContact O-N 2.97Å; Y49-T52 PolarHBondContact O-OG1 3.09Å; Y49-T52 VanDerWaalsContact O-OG1 3.1Å; Y49-L54 PolarHBondContact N-O 3.34Å; Y49-L78 HydrophobicContact CE1-CD1 4.39Å; Y49-F106 HydrophobicContact CD1-CD1 4.38Å; Y49-F106 AromaticContact CD1-CE1 4Å; Y49-F106 HydrophobicContact CD1-CE1 4Å; Y49-F106 HydrophobicContact CD1-CZ 4.21Å; Y49-F106 HydrophobicContact CD2-CB 4.03Å; Y49-F106 AromaticContact CD2-CD1 3.54Å; Y49-F106 HydrophobicContact CD2-CD1 3.54Å; Y49-F106 HydrophobicContact CD2-CD2 4.14Å; Y49-F106 AromaticContact CD2-CE1 3.99Å; Y49-F106 HydrophobicContact CD2-CE1 3.99Å; Y49-F106 AromaticContact CD2-CG 3.62Å; Y49-F106 HydrophobicContact CD2-CG 3.62Å; Y49-F106 HydrophobicContact CD2-CZ 4.46Å; Y49-F106 HydrophobicContact CE1-CE1 4.38Å; Y49-F106 AromaticContact CE2-CD1 3.87Å; Y49-F106 HydrophobicContact CE2-CD1 3.87Å; Y49-F106 HydrophobicContact CE2-CE1 4.38Å; Y49-F106 HydrophobicContact CE2-CG 4.3Å; Y49-F106 AromaticContact CG-CD1 3.83Å; Y49-F106 HydrophobicContact CG-CD1 3.83Å; Y49-F106 HydrophobicContact CG-CD2 4.12Å; Y49-F106 AromaticContact CG-CE1 3.79Å; Y49-F106 HydrophobicContact CG-CE1 3.79Å; Y49-F106 HydrophobicContact CG-CE2 4.08Å; Y49-F106 AromaticContact CG-CG 3.99Å; Y49-F106 HydrophobicContact CG-CG 3.99Å; Y49-F106 AromaticContact CG-CZ 3.91Å; Y49-F106 HydrophobicContact CG-CZ 3.91Å; Y49-G110 WeakPolarHBondContact OH-CA 3.4Å; Y49-K111 HydrophobicContact CE1-CB 4.23Å; Y49-K111 HydrophobicContact CE1-CD 4.39Å; Y49-K111 HydrophobicContact CE1-CG 4.02Å; Y49-K111 PolarHBondContact OH-N 3.49Å; Y49-Q196 PolarHBondContact OH-O 2.92Å; Y49-T198 HydrophobicContact CE2-CG2 3.84Å
50P89.6Confident78.2Confident36 Ų3661 Ų6123%0.23435%0.352CS..THydrogen-bonded Turntrans-52.5116-165.9-3236.5000115.4K111 R195 Q196P50-K111 WeakPolarHBondContact O-CD 3.3Å; P50-K111 VanDerWaalsContact O-CE 3.26Å; P50-K111 WeakPolarHBondContact O-CE 3.31Å; P50-K111 PolarHBondContact O-NZ 2.99Å; P50-R195 HydrophobicContact CG-CB 3.77Å; P50-Q196 HydrophobicContact CB-CG 4.46Å; P50-Q196 HydrophobicContact CG-CG 4.49Å
51G87.9Confident80.1Confident72 Ų7264.6 Ų64.674%0.74236%0.355SS*.THydrogen-bonded Turntrans71.730.817900000114Y49 K111Y49-G51 PolarHBondContact O-N 3.39Å; G51-K111 VanDerWaalsContact CA-NZ 3.27Å; G51-K111 PolarHBondContact O-NZ 3.29Å
52T89Confident82Confident33 Ų3366 Ų6620%0.20234%0.343CS..SBendtrans-134.2174.2167.4790000108.3A48 Y49 L54 L78A48-T52 WeakPolarHBondContact CB-O 3.32Å; Y49-T52 HydrophobicContact CD1-CG2 3.96Å; Y49-T52 PolarHBondContact O-N 2.97Å; Y49-T52 PolarHBondContact O-OG1 3.09Å; Y49-T52 VanDerWaalsContact O-OG1 3.1Å; T52-L54 PolarHBondContact OG1-N 3.27Å; T52-L78 HydrophobicContact CG2-CD2 3.9Å
53E86.1Confident84Confident193 Ų19360.9 Ų60.990%0.90232%0.319SS*.SBendtrans-98.72.2171.8-61.9-175.7167.200112.3
54L89.6Confident86.1Confident20 Ų2060.6 Ų60.611%0.10532%0.316CS..SBendtrans-79.4140.6-175.9-64.8-175.7000111.5A48 Y49 T52 Q56 N77 L78 F81 F106A48-L54 CarbonylContact C-O 3.59Å; A48-L54 VanDerWaalsContact CA-O 3.32Å; A48-L54 WeakPolarHBondContact CA-O 3.49Å; Y49-L54 PolarHBondContact N-O 3.34Å; T52-L54 PolarHBondContact OG1-N 3.27Å; L54-Q56 PolarHBondContact O-N 3.4Å; L54-N77 WeakPolarHBondContact CD1-O 3.46Å; L54-L78 HydrophobicContact CD1-CD2 3.54Å; L54-L78 HydrophobicContact CD1-CG 4.28Å; L54-L78 HydrophobicContact CG-CD2 4.46Å; L54-F81 HydrophobicContact CD1-CD2 3.56Å; L54-F81 HydrophobicContact CD1-CE2 3.93Å; L54-F81 HydrophobicContact CD1-CG 4.15Å; L54-F81 HydrophobicContact CD2-CD1 4.04Å; L54-F81 HydrophobicContact CD2-CD2 3.68Å; L54-F81 HydrophobicContact CD2-CE1 3.83Å; L54-F81 HydrophobicContact CD2-CE2 3.47Å; L54-F81 VanDerWaalsContact CD2-CE2 3.47Å; L54-F81 HydrophobicContact CD2-CG 3.95Å; L54-F81 HydrophobicContact CD2-CZ 3.52Å; L54-F81 HydrophobicContact CG-CD2 4.29Å; L54-F81 HydrophobicContact CG-CE2 4.36Å; L54-F106 HydrophobicContact CB-CE2 3.79Å; L54-F106 HydrophobicContact CB-CZ 4.07Å; L54-F106 HydrophobicContact CD1-CZ 4.08Å
55P91.4Very high87.7Confident18 Ų1857.9 Ų57.912%0.11730%0.298CS..BIsolated β-bridgetrans-72.4125.1-174.529-34.9000112.2A7 L19 A20 W47 A76 F106A7-P55 HydrophobicContact CB-CB 3.5Å; A7-P55 VanDerWaalsContact CB-CB 3.5Å; A7-P55 HydrophobicContact CB-CG 3.52Å; L19-P55 HydrophobicContact CB-CG 4.08Å; L19-P55 HydrophobicContact CD1-CG 4.45Å; A20-P55 HydrophobicContact CB-CG 4.15Å; W47-P55 CarbonylContact O-C 3.58Å; W47-P55 WeakPolarHBondContact O-CA 3.45Å; P55-A76 HydrophobicContact CG-CB 3.86Å; P55-A76 WeakPolarHBondContact O-CB 3.48Å; P55-F106 WeakPolarHBondContact O-CD2 3.32Å
56Q93.8Very high89.1Confident21 Ų2152.8 Ų52.810%0.09828%0.279CS..  trans-102.8112.8162.2178.5167.332.800109.5W47 L54 Q58 T104 G105 F106W47-Q56 PolarHBondContact O-N 2.93Å; L54-Q56 PolarHBondContact O-N 3.4Å; Q56-Q58 PolarHBondContact O-NE2 3.34Å; Q56-Q58 VanDerWaalsContact O-NE2 3.08Å; Q56-T104 PolarHBondContact NE2-O 3.35Å; Q56-G105 WeakPolarHBondContact CA-O 3.22Å; Q56-F106 HydrophobicContact CB-CB 4.34Å; Q56-F106 HydrophobicContact CB-CD2 4.15Å; Q56-F106 HydrophobicContact CG-CB 4.06Å
57L93.6Very high90.2Very high4 Ų453.1 Ų53.12%0.02129%0.286CS..  trans-58.9140.5-179.4-66.5165.7000111.1Q5 A20 L22 L59 Y73 E74 T75 G105Q5-L57 HydrophobicContact CB-CD2 4.07Å; A20-L57 HydrophobicContact CB-CD1 4.07Å; A20-L57 HydrophobicContact CB-CD2 3.95Å; A20-L57 HydrophobicContact CB-CG 3.89Å; L22-L57 HydrophobicContact CB-CD1 3.91Å; L22-L57 HydrophobicContact CB-CD2 4.05Å; L22-L57 HydrophobicContact CB-CG 4.43Å; L57-L59 HydrophobicContact CB-CD1 4.39Å; L57-L59 PolarHBondContact O-N 3.47Å; L57-Y73 HydrophobicContact CD1-CD2 4.24Å; L57-Y73 HydrophobicContact CD1-CE2 4.02Å; L57-E74 VanDerWaalsContact CD1-O 3.29Å; L57-E74 WeakPolarHBondContact CD1-O 3.4Å; L57-T75 HydrophobicContact CD1-CG2 4.05Å; L57-G105 PolarHBondContact N-O 2.93Å
58Q89.5Confident90.7Very high82 Ų8252.3 Ų52.338%0.38329%0.288SS..  trans-95.597179.4-63.4-57.7-59.900109.7Q5 W47 Q56 P60Q5-Q58 PolarHBondContact NE2-O 2.89Å; Q5-Q58 VanDerWaalsContact OE1-N 3.13Å; W47-Q58 HydrophobicContact CD2-CG 4.19Å; W47-Q58 HydrophobicContact CG-CG 3.94Å; Q56-Q58 PolarHBondContact O-NE2 3.34Å; Q56-Q58 VanDerWaalsContact O-NE2 3.08Å; Q58-P60 WeakPolarHBondContact O-CD 3.48Å
59L90.7Very high90.8Very high18 Ų1858.2 Ų58.29%0.09431%0.313CS..  trans-82.6126.6178.1-64.895000111.1L22 L57 L63 K64 Y73 R103 G105L22-L59 HydrophobicContact CD2-CG 4.17Å; L57-L59 HydrophobicContact CB-CD1 4.39Å; L57-L59 PolarHBondContact O-N 3.47Å; L59-L63 HydrophobicContact CB-CB 4.38Å; L59-L63 HydrophobicContact CD2-CB 4.23Å; L59-K64 HydrophobicContact CB-CG 3.9Å; L59-Y73 HydrophobicContact CD1-CE2 4.33Å; L59-Y73 HydrophobicContact CD2-CE2 4.08Å; L59-R103 HydrophobicContact CD2-CB 3.67Å; L59-G105 VanDerWaalsContact CD1-CA 3.43Å; L59-G105 VanDerWaalsContact CD1-N 3.31Å
60P89.1Confident90.9Very high38 Ų3859.6 Ų59.625%0.24732%0.32CS..  trans-47.7145.2159-26.833.4000111.5Q58 Y62 L63 K64Q58-P60 WeakPolarHBondContact O-CD 3.48Å; P60-Y62 HydrophobicContact CB-CD1 3.66Å; P60-Y62 HydrophobicContact CB-CE1 3.37Å; P60-Y62 HydrophobicContact CG-CE1 4.12Å; P60-Y62 PolarHBondContact O-N 3.21Å; P60-L63 HydrophobicContact CB-CD1 4.45Å; P60-L63 HydrophobicContact CB-CG 4.31Å; P60-L63 HydrophobicContact CG-CD1 4.01Å; P60-L63 HydrophobicContact CG-CG 4.39Å; P60-L63 PolarHBondContact O-N 3.45Å; P60-K64 PolarHBondContact O-N 3.38Å
61Q87.7Confident91.2Very high125 Ų12562.3 Ų62.358%0.58433%0.333SS*.THydrogen-bonded Turntrans-55.5-34.3-171.7-175.356.348.600113.5K64Q61-K64 WeakPolarHBondContact O-CB 3.44Å
62Y88.7Confident91.5Very high87 Ų8764.2 Ų64.234%0.34132%0.317SS..THydrogen-bonded Turntrans-71.5-32.5178.172.8-84.5000113Y24 P60 K64 S65 T68Y24-Y62 WeakPolarHBondContact CD2-OH 3.16Å; Y24-Y62 VanDerWaalsContact CE2-OH 3.29Å; Y24-Y62 WeakPolarHBondContact CE2-OH 3.1Å; P60-Y62 HydrophobicContact CB-CD1 3.66Å; P60-Y62 HydrophobicContact CB-CE1 3.37Å; P60-Y62 HydrophobicContact CG-CE1 4.12Å; P60-Y62 PolarHBondContact O-N 3.21Å; Y62-K64 VanDerWaalsContact C-N 3.26Å; Y62-K64 PolarHBondContact O-N 3.02Å; Y62-S65 PolarHBondContact O-N 3.44Å; Y62-T68 HydrophobicContact CD2-CG2 4.34Å; Y62-T68 PolarHBondContact O-OG1 3.15Å; Y62-T68 VanDerWaalsContact O-OG1 3.09Å
63L93.1Very high91.8Very high2 Ų265.4 Ų65.41%0.0132%0.318CS..THydrogen-bonded Turntrans-75.9-14.2179.2-64.5-172.5000113.9Y24 L59 P60 S65 T68 L70 R103Y24-L63 HydrophobicContact CD1-CD1 3.26Å; Y24-L63 HydrophobicContact CD2-CD1 3.55Å; Y24-L63 HydrophobicContact CD2-CD2 4.45Å; Y24-L63 HydrophobicContact CE1-CD1 3.55Å; Y24-L63 HydrophobicContact CE2-CD1 3.83Å; Y24-L63 HydrophobicContact CG-CD1 3.26Å; Y24-L63 HydrophobicContact CG-CD2 4.38Å; Y24-L63 HydrophobicContact CG-CG 4.44Å; L59-L63 HydrophobicContact CB-CB 4.38Å; L59-L63 HydrophobicContact CD2-CB 4.23Å; P60-L63 HydrophobicContact CB-CD1 4.45Å; P60-L63 HydrophobicContact CB-CG 4.31Å; P60-L63 HydrophobicContact CG-CD1 4.01Å; P60-L63 HydrophobicContact CG-CG 4.39Å; P60-L63 PolarHBondContact O-N 3.45Å; L63-S65 PolarHBondContact O-N 3.35Å; L63-T68 HydrophobicContact CD2-CG2 3.57Å; L63-L70 HydrophobicContact CB-CD2 4.28Å; L63-L70 HydrophobicContact CD1-CD2 3.96Å; L63-L70 HydrophobicContact CD2-CD2 3.73Å; L63-L70 HydrophobicContact CG-CD2 4.22Å; L63-R103 PolarHBondContact O-NH1 2.96Å
64K94Very high92.1Very high57 Ų5760.3 Ų60.325%0.24830%0.295CS..THydrogen-bonded Turntrans-64.6-28173.2-67.8-171.9169.1-168.60112.1L59 P60 Q61 Y62 L66 E102 R103L59-K64 HydrophobicContact CB-CG 3.9Å; P60-K64 PolarHBondContact O-N 3.38Å; Q61-K64 WeakPolarHBondContact O-CB 3.44Å; Y62-K64 VanDerWaalsContact C-N 3.26Å; Y62-K64 PolarHBondContact O-N 3.02Å; K64-L66 PolarHBondContact O-N 3.05Å; K64-E102 HydrophobicContact CB-CB 4.2Å; K64-E102 IonicContact NZ-OE2 3.75Å; K64-E102 CarbonylContact O-C 3.58Å; K64-E102 WeakPolarHBondContact O-CA 3.49Å; K64-R103 PolarHBondContact O-N 3.34Å
65S93.2Very high92.3Very high36 Ų3660.2 Ų60.225%0.25230%0.295SS..SBendtrans-65.1128176.6-178.80000111.2Y62 L63 D67 T68 R103Y62-S65 PolarHBondContact O-N 3.44Å; L63-S65 PolarHBondContact O-N 3.35Å; S65-D67 PolarHBondContact O-N 2.99Å; S65-D67 PolarHBondContact OG-N 2.66Å; S65-T68 WeakPolarHBondContact O-CB 3.36Å; S65-T68 PolarHBondContact O-N 3.38Å; S65-R103 PolarHBondContact O-NH1 2.78Å
66L92.1Very high92.4Very high72 Ų7259.5 Ų59.538%0.37729%0.291SS..THydrogen-bonded Turntrans-60.4-26.6176.6-61.1178.3000112.9K64 T68 N99 K100 R103K64-L66 PolarHBondContact O-N 3.05Å; L66-T68 PolarHBondContact O-N 3.28Å; L66-N99 WeakPolarHBondContact CD1-O 3.5Å; L66-K100 VanDerWaalsContact CD1-C 3.48Å; L66-K100 WeakPolarHBondContact CD1-O 3.4Å; L66-R103 HydrophobicContact CD2-CG 3.78Å; L66-R103 PolarHBondContact O-NH2 2.83Å
67D91.6Very high92.3Very high124 Ų12459.2 Ų59.266%0.66329%0.29SS*.THydrogen-bonded Turntrans-70.5-16178.8-52.9-34.5000112.5S65 K256S65-D67 PolarHBondContact O-N 2.99Å; S65-D67 PolarHBondContact OG-N 2.66Å; D67-K256 IonicContact OD2-NZ 2.98Å; D67-K256 PolarHBondContact OD2-NZ 3.48Å
68T91.5Very high92.2Very high38 Ų3861.3 Ų61.323%0.23330%0.301CS..SBendtrans-83.9133-179.9-53.50000111.3Y62 L63 S65 L66 R103Y62-T68 HydrophobicContact CD2-CG2 4.34Å; Y62-T68 PolarHBondContact O-OG1 3.15Å; Y62-T68 VanDerWaalsContact O-OG1 3.09Å; L63-T68 HydrophobicContact CD2-CG2 3.57Å; S65-T68 WeakPolarHBondContact O-CB 3.36Å; S65-T68 PolarHBondContact O-N 3.38Å; L66-T68 PolarHBondContact O-N 3.28Å; T68-R103 PolarHBondContact O-NH1 2.83Å; T68-R103 PolarHBondContact O-NH2 2.93Å
69M91.7Very high92.2Very high146 Ų14659.7 Ų59.772%0.71929%0.293SS*.  trans-73.6133.5177.4-172.8177.57300111.2
70L94.3Very high91.9Very high30 Ų3059.5 Ų59.516%0.15729%0.293CS..  trans-117.7143.9171.5-62.8177.9000108.5L22 L63 Y73L22-L70 HydrophobicContact CD1-CD1 3.96Å; L22-L70 HydrophobicContact CD1-CD2 3.85Å; L22-L70 HydrophobicContact CD1-CG 4.46Å; L63-L70 HydrophobicContact CB-CD2 4.28Å; L63-L70 HydrophobicContact CD1-CD2 3.96Å; L63-L70 HydrophobicContact CD2-CD2 3.73Å; L63-L70 HydrophobicContact CG-CD2 4.22Å; L70-Y73 HydrophobicContact CD1-CD2 3.87Å; L70-Y73 HydrophobicContact CD1-CG 3.77Å
71L96Very high91.4Very high93 Ų9359.8 Ų59.849%0.48729%0.291SS..SBendtrans-76.8-36175.8-59174.4000110.6V2 C23V2-L71 HydrophobicContact CB-CD1 4.39Å; V2-L71 HydrophobicContact CG1-CD1 3.75Å; V2-L71 HydrophobicContact CG2-CD1 3.73Å; C23-L71 HydrophobicContact CB-CB 4.13Å; C23-L71 WeakPolarHBondContact O-CA 3.49Å; C23-L71 WeakPolarHBondContact O-CB 3.35Å; C23-L71 PolarHBondContact O-N 3.15Å
72W94.6Very high90.2Very high111 Ų11159.1 Ų59.142%0.4229%0.291SS..EExtended strand (participates in β ladder)trans-151.3134.5173.2-168.2-5.2000109.1F6 A21 L22 C23 E74F6-W72 HydrophobicContact CE1-CE3 4.18Å; F6-W72 AromaticContact CE1-CZ3 3.94Å; F6-W72 HydrophobicContact CE1-CZ3 3.94Å; A21-W72 HydrophobicContact CB-CD2 3.93Å; A21-W72 HydrophobicContact CB-CE3 4.36Å; A21-W72 HydrophobicContact CB-CG 4.3Å; A21-W72 HydrophobicContact CB-CZ2 4.12Å; L22-W72 CarbonylContact C-O 3.54Å; L22-W72 WeakPolarHBondContact CA-O 3.33Å; C23-W72 HydrophobicContact CB-CB 3.98Å; C23-W72 PolarHBondContact N-O 2.79Å; C23-W72 PolarHBondContact O-N 2.93Å; C23-W72 VanDerWaalsContact O-N 3.14Å; W72-E74 PolarHBondContact NE1-OE2 3.23Å
73Y95.1Very high88.7Confident58 Ų5857.3 Ų57.323%0.22730%0.299CS..EExtended strand (participates in β ladder)trans-143.2109.8171.8-175.9-112.8000110.6A21 L22 L57 L59 L70 T75 R103 G105 D199A21-Y73 CarbonylContact O-C 3.57Å; A21-Y73 WeakPolarHBondContact O-CA 3.31Å; L22-Y73 HydrophobicContact CD1-CD2 4Å; L57-Y73 HydrophobicContact CD1-CD2 4.24Å; L57-Y73 HydrophobicContact CD1-CE2 4.02Å; L59-Y73 HydrophobicContact CD1-CE2 4.33Å; L59-Y73 HydrophobicContact CD2-CE2 4.08Å; L70-Y73 HydrophobicContact CD1-CD2 3.87Å; L70-Y73 HydrophobicContact CD1-CG 3.77Å; Y73-T75 HydrophobicContact CD2-CG2 4.46Å; Y73-T75 HydrophobicContact CE1-CG2 3.78Å; Y73-T75 HydrophobicContact CE2-CG2 3.71Å; Y73-T75 VanDerWaalsContact OH-CG2 3.27Å; Y73-T75 WeakPolarHBondContact OH-CG2 3.37Å; Y73-R103 HydrophobicContact CE1-CB 4.39Å; Y73-R103 HydrophobicContact CE1-CG 4.24Å; Y73-G105 VanDerWaalsContact OH-CA 3.26Å; Y73-G105 WeakPolarHBondContact OH-CA 3.29Å; Y73-G105 PolarHBondContact OH-N 2.85Å; Y73-D199 WeakPolarHBondContact CE1-OD2 3.5Å; Y73-D199 VanDerWaalsContact CZ-OD2 3.29Å; Y73-D199 VanDerWaalsContact OH-CG 3.31Å; Y73-D199 PolarHBondContact OH-OD1 2.81Å; Y73-D199 PolarHBondContact OH-OD2 3.16Å
74E93Very high86.9Confident87 Ų8768.8 Ų68.841%0.40734%0.344SS..EExtended strand (participates in β ladder)trans-136.6130.7177.8-175.2169.2-178.900108.1A20 A21 L57 W72A20-E74 CarbonylContact C-O 3.59Å; A20-E74 WeakPolarHBondContact CA-O 3.04Å; A21-E74 HydrophobicContact CB-CB 4.43Å; A21-E74 PolarHBondContact N-O 2.85Å; A21-E74 PolarHBondContact O-N 3.17Å; A21-E74 VanDerWaalsContact O-O 3.13Å; L57-E74 VanDerWaalsContact CD1-O 3.29Å; L57-E74 WeakPolarHBondContact CD1-O 3.4Å; W72-E74 PolarHBondContact NE1-OE2 3.23Å
75T94.3Very high85Confident18 Ų1873.9 Ų73.911%0.1137%0.374CS..  trans-120.4147-170.849.70000111.2L19 L57 Y73 G105 S107L19-T75 CarbonylContact O-C 3.46Å; L57-T75 HydrophobicContact CD1-CG2 4.05Å; Y73-T75 HydrophobicContact CD2-CG2 4.46Å; Y73-T75 HydrophobicContact CE1-CG2 3.78Å; Y73-T75 HydrophobicContact CE2-CG2 3.71Å; Y73-T75 VanDerWaalsContact OH-CG2 3.27Å; Y73-T75 WeakPolarHBondContact OH-CG2 3.37Å; T75-G105 VanDerWaalsContact CG2-C 3.45Å; T75-S107 PolarHBondContact O-OG 2.93Å; T75-S107 WeakPolarHBondContact OG1-CB 3.25Å; T75-S107 PolarHBondContact OG1-N 2.89Å; T75-S107 PolarHBondContact OG1-OG 2.82Å
76A92.8Very high83.3Confident3 Ų374 Ų743%0.02538%0.375CS..  trans-69.4157.7166.100000110.2L19 P55 F106 S107L19-A76 WeakPolarHBondContact O-CA 3.12Å; L19-A76 PolarHBondContact O-N 2.89Å; L19-A76 VanDerWaalsContact O-N 3.15Å; P55-A76 HydrophobicContact CG-CB 3.86Å; P55-A76 WeakPolarHBondContact O-CB 3.48Å; A76-F106 HydrophobicContact CB-CD2 4.33Å; A76-F106 HydrophobicContact CB-CE2 3.86Å; A76-F106 WeakPolarHBondContact O-CD2 3.42Å; A76-S107 PolarHBondContact O-N 3.02Å; A76-S107 PolarHBondContact O-OG 2.89Å
77N92.5Very high81.8Confident14 Ų1479.8 Ų79.88%0.07539%0.392CS..  trans-146.5160176.763.185000108.9L54 E79 S80 F81 W96 S107L54-N77 WeakPolarHBondContact CD1-O 3.46Å; N77-E79 PolarHBondContact OD1-N 2.86Å; N77-S80 PolarHBondContact ND2-OG 2.88Å; N77-S80 WeakPolarHBondContact OD1-CB 3.45Å; N77-S80 PolarHBondContact OD1-N 3.12Å; N77-S80 PolarHBondContact OD1-OG 3.07Å; N77-F81 VanDerWaalsContact O-CD2 3.28Å; N77-F81 WeakPolarHBondContact O-CD2 3.42Å; N77-W96 HydrophobicContact CB-CH2 4.03Å; N77-W96 HydrophobicContact CB-CZ3 4.25Å; N77-S107 WeakPolarHBondContact CA-O 3.21Å; N77-S107 VanDerWaalsContact CB-O 3.31Å; N77-S107 WeakPolarHBondContact CB-O 3.44Å
78L90.7Very high80.6Confident49 Ų4974.5 Ų74.526%0.25736%0.364SS..SBendtrans-77.7-28.8-179.9-74.4171.1000112.2Y49 T52 L54 S80 F81 F106Y49-L78 HydrophobicContact CE1-CD1 4.39Å; T52-L78 HydrophobicContact CG2-CD2 3.9Å; L54-L78 HydrophobicContact CD1-CD2 3.54Å; L54-L78 HydrophobicContact CD1-CG 4.28Å; L54-L78 HydrophobicContact CG-CD2 4.46Å; L78-S80 PolarHBondContact O-N 3.01Å; L78-F81 CarbonylContact O-C 3.52Å; L78-F81 PolarHBondContact O-N 2.92Å; L78-F106 HydrophobicContact CG-CE1 4.25Å; L78-F106 HydrophobicContact CG-CZ 4.24Å
79E89Confident79.6Confident47 Ų4780.5 Ų80.522%0.2238%0.383CS..THydrogen-bonded Turntrans-65-28.2-175.2-65.387.6154.300112.7N77 F81 V91 W96 G108 K109 Y115N77-E79 PolarHBondContact OD1-N 2.86Å; E79-F81 PolarHBondContact O-N 2.62Å; E79-V91 HydrophobicContact CB-CG1 4.3Å; E79-V91 HydrophobicContact CB-CG2 4.2Å; E79-W96 HydrophobicContact CB-CH2 4.21Å; E79-W96 HydrophobicContact CB-CZ2 4.03Å; E79-W96 HydrophobicContact CG-CH2 4.32Å; E79-W96 HydrophobicContact CG-CZ2 3.95Å; E79-G108 VanDerWaalsContact OE1-CA 3.29Å; E79-G108 WeakPolarHBondContact OE1-CA 3.39Å; E79-G108 WeakPolarHBondContact OE2-CA 3.14Å; E79-K109 WeakPolarHBondContact OE1-CB 3.18Å; E79-K109 PolarHBondContact OE1-N 2.62Å; E79-Y115 PolarHBondContact OE1-OH 3.07Å
80S84.7Confident78.7Confident14 Ų1482.1 Ų82.110%0.09839%0.389CS..THydrogen-bonded Turntrans-71.3-13.8172.7-77.40000113.1N77 L78 S88 R89N77-S80 PolarHBondContact ND2-OG 2.88Å; N77-S80 WeakPolarHBondContact OD1-CB 3.45Å; N77-S80 PolarHBondContact OD1-N 3.12Å; N77-S80 PolarHBondContact OD1-OG 3.07Å; L78-S80 PolarHBondContact O-N 3.01Å; S80-S88 CarbonylContact O-C 3.58Å; S80-S88 VanDerWaalsContact O-CA 3.27Å; S80-S88 WeakPolarHBondContact O-CA 3.42Å; S80-R89 VanDerWaalsContact CB-O 3.25Å; S80-R89 WeakPolarHBondContact CB-O 3.47Å; S80-R89 PolarHBondContact O-N 3.17Å; S80-R89 PolarHBondContact OG-O 2.67Å
81F79.4Confident78Confident45 Ų4583.1 Ų83.120%0.19740%0.396CS..  trans-120.293.3-175.3-65.5-94.4000111.5L19 L54 N77 L78 E79 G83L19-F81 HydrophobicContact CD1-CZ 3.87Å; L19-F81 HydrophobicContact CD2-CE1 4.43Å; L19-F81 HydrophobicContact CD2-CE2 4.43Å; L19-F81 HydrophobicContact CD2-CZ 3.6Å; L19-F81 HydrophobicContact CG-CZ 4.3Å; L54-F81 HydrophobicContact CD1-CD2 3.56Å; L54-F81 HydrophobicContact CD1-CE2 3.93Å; L54-F81 HydrophobicContact CD1-CG 4.15Å; L54-F81 HydrophobicContact CD2-CD1 4.04Å; L54-F81 HydrophobicContact CD2-CD2 3.68Å; L54-F81 HydrophobicContact CD2-CE1 3.83Å; L54-F81 HydrophobicContact CD2-CE2 3.47Å; L54-F81 VanDerWaalsContact CD2-CE2 3.47Å; L54-F81 HydrophobicContact CD2-CG 3.95Å; L54-F81 HydrophobicContact CD2-CZ 3.52Å; L54-F81 HydrophobicContact CG-CD2 4.29Å; L54-F81 HydrophobicContact CG-CE2 4.36Å; N77-F81 VanDerWaalsContact O-CD2 3.28Å; N77-F81 WeakPolarHBondContact O-CD2 3.42Å; L78-F81 CarbonylContact O-C 3.52Å; L78-F81 PolarHBondContact O-N 2.92Å; E79-F81 PolarHBondContact O-N 2.62Å; F81-G83 PolarHBondContact O-N 3.21Å; F81-G83 VanDerWaalsContact O-N 3.07Å
82N62.7Low77.2Confident110 Ų11082.6 Ų82.659%0.58841%0.405SS*.  trans-82.474.3174.2-84.7-11.3000112S86N82-S86 WeakPolarHBondContact O-CB 3.35Å; N82-S86 PolarHBondContact O-OG 3.03Å
83G56.6Low76.6Confident50 Ų5080.9 Ų80.952%0.51541%0.407SS..SBendtrans85171.7174.800000115.1F81 N85 S86F81-G83 PolarHBondContact O-N 3.21Å; F81-G83 VanDerWaalsContact O-N 3.07Å; G83-N85 VanDerWaalsContact C-N 3.3Å; G83-N85 PolarHBondContact O-N 3.12Å; G83-N85 VanDerWaalsContact O-N 3.15Å; G83-S86 PolarHBondContact O-N 2.86Å
84Y54.9Low76Confident242 Ų24284.2 Ų84.295%0.94943%0.433SS*.THydrogen-bonded Turntrans-60-29.7-162.5-70.2-78.7000115.8
85N55.1Low75.7Confident164 Ų16491.2 Ų91.288%0.87746%0.456SS*.THydrogen-bonded Turntrans-110.87.7-176-65.7-23.2000113.3G83G83-N85 VanDerWaalsContact C-N 3.3Å; G83-N85 PolarHBondContact O-N 3.12Å; G83-N85 VanDerWaalsContact O-N 3.15Å
86S56.2Low75.6Confident39 Ų3991.8 Ų91.827%0.27346%0.456SS..PPolyproline II helixtrans-84.2123-179.6-74.30000110N82 G83 S88N82-S86 WeakPolarHBondContact O-CB 3.35Å; N82-S86 PolarHBondContact O-OG 3.03Å; G83-S86 PolarHBondContact O-N 2.86Å; S86-S88 PolarHBondContact O-N 2.96Å
87R62.1Low75.7Confident194 Ų19495.7 Ų95.773%0.73248%0.476SS*.PPolyproline II helixtrans-51.6136.9160.9-67.2-175.4-178.8-173.20.1108.3R89R87-R89 PolarHBondContact O-N 3.36Å
88S64.5Low75.8Confident12 Ų12104.7 Ų104.78%0.08451%0.509CS..PPolyproline II helixtrans-49.8140.1173.149.10000110.6E9 R17 S80 S86E9-S88 PolarHBondContact OE2-OG 2.86Å; R17-S88 VanDerWaalsContact CD-OG 3.3Å; R17-S88 WeakPolarHBondContact CD-OG 3.37Å; R17-S88 PolarHBondContact NH1-O 3.42Å; R17-S88 PolarHBondContact NH1-OG 3.36Å; S80-S88 CarbonylContact O-C 3.58Å; S80-S88 VanDerWaalsContact O-CA 3.27Å; S80-S88 WeakPolarHBondContact O-CA 3.42Å; S86-S88 PolarHBondContact O-N 2.96Å
89R71.4Confident76Confident165 Ų165102.5 Ų102.562%0.62350%0.497SS*.  trans-118.4149.4175.6-65.9-175.9-177.4-176-0.1110.4S80 R87S80-R89 VanDerWaalsContact CB-O 3.25Å; S80-R89 WeakPolarHBondContact CB-O 3.47Å; S80-R89 PolarHBondContact O-N 3.17Å; S80-R89 PolarHBondContact OG-O 2.67Å; R87-R89 PolarHBondContact O-N 3.36Å
90E72.5Confident76.3Confident180 Ų180108.2 Ų108.284%0.84152%0.522SS*.  trans-68.5135.1168.4-69.8-178.7-177.400109.7
91V79.1Confident76.7Confident51 Ų51109.5 Ų109.531%0.30953%0.525SS..  trans-121.2134.5178.9179.30000107.7E79 T93 W96E79-V91 HydrophobicContact CB-CG1 4.3Å; E79-V91 HydrophobicContact CB-CG2 4.2Å; V91-T93 WeakPolarHBondContact O-CG2 3.36Å; V91-T93 PolarHBondContact O-N 3.16Å; V91-W96 HydrophobicContact CG1-CH2 4.47Å; V91-W96 HydrophobicContact CG1-CZ2 3.81Å
92A79.2Confident77.5Confident82 Ų82108 Ų10868%0.67852%0.518SS*.  trans-69.1105.9176.100000110.3
93T82.8Confident79.1Confident74 Ų74104.5 Ų104.545%0.45450%0.496SS..  trans-91.9-2.3-176.960.90000113.8V91 R95 W96V91-T93 WeakPolarHBondContact O-CG2 3.36Å; V91-T93 PolarHBondContact O-N 3.16Å; T93-R95 PolarHBondContact O-N 3.31Å; T93-R95 VanDerWaalsContact O-N 3.12Å; T93-W96 HydrophobicContact CG2-CD2 4.08Å; T93-W96 HydrophobicContact CG2-CE3 3.69Å; T93-W96 HydrophobicContact CG2-CH2 3.91Å; T93-W96 HydrophobicContact CG2-CZ2 4.27Å; T93-W96 HydrophobicContact CG2-CZ3 3.59Å; T93-W96 WeakPolarHBondContact O-CB 3.24Å; T93-W96 PolarHBondContact O-N 3.4Å
94T81.6Confident81Confident129 Ų129102.7 Ų102.779%0.79148%0.476SS*.THydrogen-bonded Turntrans-60.5-26.5-173.553.40000114
95R86.6Confident82.9Confident233 Ų23391.2 Ų91.288%0.87943%0.431SS*.THydrogen-bonded Turntrans-92.6-3.5178.8-62.3-175.4-178.9-177.70.5113.7T93 I97T93-R95 PolarHBondContact O-N 3.31Å; T93-R95 VanDerWaalsContact O-N 3.12Å; R95-I97 PolarHBondContact O-N 2.78Å
96W92.8Very high84.9Confident30 Ų3083.4 Ų83.411%0.11439%0.389CS..PPolyproline II helixtrans-73.9128.9-177.4-67.4-2.7000110.7N77 E79 V91 T93 R98 G108 Y115 N200N77-W96 HydrophobicContact CB-CH2 4.03Å; N77-W96 HydrophobicContact CB-CZ3 4.25Å; E79-W96 HydrophobicContact CB-CH2 4.21Å; E79-W96 HydrophobicContact CB-CZ2 4.03Å; E79-W96 HydrophobicContact CG-CH2 4.32Å; E79-W96 HydrophobicContact CG-CZ2 3.95Å; V91-W96 HydrophobicContact CG1-CH2 4.47Å; V91-W96 HydrophobicContact CG1-CZ2 3.81Å; T93-W96 HydrophobicContact CG2-CD2 4.08Å; T93-W96 HydrophobicContact CG2-CE3 3.69Å; T93-W96 HydrophobicContact CG2-CH2 3.91Å; T93-W96 HydrophobicContact CG2-CZ2 4.27Å; T93-W96 HydrophobicContact CG2-CZ3 3.59Å; T93-W96 WeakPolarHBondContact O-CB 3.24Å; T93-W96 PolarHBondContact O-N 3.4Å; W96-R98 PolarHBondContact O-N 3.45Å; W96-G108 VanDerWaalsContact CZ3-N 3.25Å; W96-Y115 AromaticContact CD1-CE1 3.92Å; W96-Y115 AromaticContact CD1-CZ 3.9Å; W96-Y115 AromaticContact CD2-CE1 3.97Å; W96-Y115 HydrophobicContact CD2-CE1 3.97Å; W96-Y115 AromaticContact CE2-CE1 3.95Å; W96-Y115 AromaticContact CE2-CZ 3.91Å; W96-Y115 HydrophobicContact CG-CD1 4.48Å; W96-Y115 AromaticContact CG-CE1 3.95Å; W96-Y115 HydrophobicContact CG-CE1 3.95Å; W96-Y115 AromaticContact NE1-CE1 3.93Å; W96-Y115 AromaticContact NE1-CZ 3.61Å; W96-Y115 PolarHBondContact NE1-OH 2.76Å; W96-N200 HydrophobicContact CB-CB 4.31Å; W96-N200 WeakPolarHBondContact CB-ND2 3.46Å; W96-N200 HydrophobicContact CE3-CB 4.49Å
97I94.9Very high86.8Confident86 Ų8682.1 Ų82.144%0.44138%0.38SS..PPolyproline II helixtrans-58.8137.7170.2-59.5174.7000107.7R95 N200 W202R95-I97 PolarHBondContact O-N 2.78Å; I97-N200 WeakPolarHBondContact O-CA 3.43Å; I97-N200 WeakPolarHBondContact O-CB 3.34Å; I97-N200 PolarHBondContact O-ND2 3.01Å; I97-W202 HydrophobicContact CG2-CH2 3.87Å; I97-W202 HydrophobicContact CG2-CZ3 4.18Å
98R94.3Very high88.4Confident202 Ų20272.9 Ų72.976%0.76235%0.345SS*.PPolyproline II helixtrans-99136.5177.6-65.2-175.4179.8-173-1.3110.9W96 K100 D199 W202W96-R98 PolarHBondContact O-N 3.45Å; R98-K100 PolarHBondContact O-N 2.85Å; R98-D199 CarbonylContact C-O 3.6Å; R98-D199 WeakPolarHBondContact CA-O 3.48Å; R98-W202 WeakPolarHBondContact O-CH2 3.28Å
99N96Very high89.8Confident4 Ų475.7 Ų75.72%0.02136%0.356CS..  trans-64113.3169.5-173.5-20000108.7L66 Y101 E102 Y191 T198 D199 W202L66-N99 WeakPolarHBondContact CD1-O 3.5Å; N99-Y101 VanDerWaalsContact C-N 3.28Å; N99-Y101 WeakPolarHBondContact OD1-CB 3.3Å; N99-Y101 WeakPolarHBondContact OD1-CD2 3.34Å; N99-Y101 PolarHBondContact OD1-N 2.85Å; N99-E102 PolarHBondContact OD1-N 2.97Å; N99-Y191 PolarHBondContact ND2-OH 2.82Å; N99-T198 PolarHBondContact ND2-O 3.48Å; N99-D199 WeakPolarHBondContact CB-O 3.37Å; N99-D199 PolarHBondContact N-O 2.9Å; N99-W202 HydrophobicContact CB-CD2 4.4Å; N99-W202 HydrophobicContact CB-CE3 3.62Å; N99-W202 HydrophobicContact CB-CZ3 3.82Å
100K94.3Very high90.9Very high167 Ų16768.4 Ų68.473%0.72633%0.332SS*.SBendtrans-82.8-5.1-176.9-61.9-177.5-178.8178.90113.1L66 R98L66-K100 VanDerWaalsContact CD1-C 3.48Å; L66-K100 WeakPolarHBondContact CD1-O 3.4Å; R98-K100 PolarHBondContact O-N 2.85Å
101Y94.8Very high91.8Very high41 Ų4164.4 Ų64.416%0.16131%0.312CS..SBendtrans-99.9-43.2-172.4-61.2-91.5000112.4N99 Y191 W202 I253 L255N99-Y101 VanDerWaalsContact C-N 3.28Å; N99-Y101 WeakPolarHBondContact OD1-CB 3.3Å; N99-Y101 WeakPolarHBondContact OD1-CD2 3.34Å; N99-Y101 PolarHBondContact OD1-N 2.85Å; Y101-Y191 VanDerWaalsContact CD1-CB 3.49Å; Y101-Y191 HydrophobicContact CD1-CD2 4.03Å; Y101-Y191 AromaticContact CD1-CG 3.85Å; Y101-Y191 HydrophobicContact CD1-CG 3.85Å; Y101-Y191 AromaticContact CD2-CD2 3.17Å; Y101-Y191 HydrophobicContact CD2-CD2 3.17Å; Y101-Y191 AromaticContact CD2-CE2 3.81Å; Y101-Y191 HydrophobicContact CD2-CE2 3.81Å; Y101-Y191 AromaticContact CD2-CG 3.87Å; Y101-Y191 HydrophobicContact CD2-CG 3.87Å; Y101-Y191 HydrophobicContact CE1-CD2 4.49Å; Y101-Y191 HydrophobicContact CE1-CG 4.3Å; Y101-Y191 AromaticContact CE2-CD2 3.76Å; Y101-Y191 HydrophobicContact CE2-CD2 3.76Å; Y101-Y191 HydrophobicContact CE2-CG 4.35Å; Y101-Y191 HydrophobicContact CG-CD1 4.43Å; Y101-Y191 AromaticContact CG-CD2 3.33Å; Y101-Y191 HydrophobicContact CG-CD2 3.33Å; Y101-Y191 AromaticContact CG-CE2 3.96Å; Y101-Y191 HydrophobicContact CG-CE2 3.96Å; Y101-Y191 AromaticContact CG-CG 3.59Å; Y101-Y191 HydrophobicContact CG-CG 3.59Å; Y101-W202 HydrophobicContact CE2-CZ2 4.28Å; Y101-W202 AromaticContact CE2-NE1 3.7Å; Y101-I253 HydrophobicContact CD1-CB 4.37Å; Y101-I253 HydrophobicContact CD1-CG2 4.14Å; Y101-L255 HydrophobicContact CD1-CD2 4.15Å; Y101-L255 HydrophobicContact CE1-CD1 4.48Å; Y101-L255 HydrophobicContact CE1-CD2 3.47Å; Y101-L255 VanDerWaalsContact CE1-CD2 3.47Å; Y101-L255 HydrophobicContact CE1-CG 3.56Å
102E95.2Very high92.6Very high12 Ų1262.2 Ų62.26%0.05630%0.298CS..  trans-158.4158.9-178.461.4-179.7165.900112.9K64 N99 T104 Y191 I253K64-E102 HydrophobicContact CB-CB 4.2Å; K64-E102 IonicContact NZ-OE2 3.75Å; K64-E102 CarbonylContact O-C 3.58Å; K64-E102 WeakPolarHBondContact O-CA 3.49Å; N99-E102 PolarHBondContact OD1-N 2.97Å; E102-T104 HydrophobicContact CG-CG2 4.15Å; E102-Y191 VanDerWaalsContact CD-OH 3.31Å; E102-Y191 HydrophobicContact CG-CE1 4.27Å; E102-Y191 VanDerWaalsContact CG-OH 3.27Å; E102-Y191 WeakPolarHBondContact CG-OH 3.25Å; E102-Y191 WeakPolarHBondContact OE1-CE1 3.27Å; E102-Y191 VanDerWaalsContact OE1-CZ 3.24Å; E102-Y191 PolarHBondContact OE1-OH 2.81Å; E102-I253 HydrophobicContact CG-CD1 4.43Å
103R96.1Very high93.2Very high37 Ų3761.9 Ų61.914%0.1429%0.289CS..  trans-79.2136.6156.6-58.7-172.1-17187.14.4109.5L59 L63 K64 S65 L66 T68 Y73L59-R103 HydrophobicContact CD2-CB 3.67Å; L63-R103 PolarHBondContact O-NH1 2.96Å; K64-R103 PolarHBondContact O-N 3.34Å; S65-R103 PolarHBondContact O-NH1 2.78Å; L66-R103 HydrophobicContact CD2-CG 3.78Å; L66-R103 PolarHBondContact O-NH2 2.83Å; T68-R103 PolarHBondContact O-NH1 2.83Å; T68-R103 PolarHBondContact O-NH2 2.93Å; Y73-R103 HydrophobicContact CE1-CB 4.39Å; Y73-R103 HydrophobicContact CE1-CG 4.24Å
104T96.1Very high93.8Very high13 Ų1364.5 Ų64.58%0.0830%0.296CS..  trans-113.7-11.1-173.765.20000113.3Q56 E102 F106 N197 T198 D199Q56-T104 PolarHBondContact NE2-O 3.35Å; E102-T104 HydrophobicContact CG-CG2 4.15Å; T104-F106 VanDerWaalsContact C-N 3.31Å; T104-F106 PolarHBondContact OG1-N 2.87Å; T104-F106 PolarHBondContact OG1-O 2.87Å; T104-N197 HydrophobicContact CG2-CB 4.23Å; T104-T198 VanDerWaalsContact CG2-C 3.49Å; T104-T198 WeakPolarHBondContact CG2-O 3.14Å; T104-T198 WeakPolarHBondContact OG1-CA 3.33Å; T104-D199 PolarHBondContact N-OD1 3.17Å; T104-D199 PolarHBondContact OG1-N 3.31Å; T104-D199 PolarHBondContact OG1-OD1 2.84Å
105G95.7Very high94.4Very high0 Ų062.1 Ų62.10%027%0.273CS..SBendtrans80.98.4-176.800000114.5Q56 L57 L59 Y73 T75Q56-G105 WeakPolarHBondContact CA-O 3.22Å; L57-G105 PolarHBondContact N-O 2.93Å; L59-G105 VanDerWaalsContact CD1-CA 3.43Å; L59-G105 VanDerWaalsContact CD1-N 3.31Å; Y73-G105 VanDerWaalsContact OH-CA 3.26Å; Y73-G105 WeakPolarHBondContact OH-CA 3.29Å; Y73-G105 PolarHBondContact OH-N 2.85Å; T75-G105 VanDerWaalsContact CG2-C 3.45Å
106F96.6Very high94.9Very high0 Ų051 Ų510%023%0.231CC..  trans-147.6136.2178.6-157.6-98.4000109.8Y49 L54 P55 Q56 A76 L78 T104 T198 D199Y49-F106 HydrophobicContact CD1-CD1 4.38Å; Y49-F106 AromaticContact CD1-CE1 4Å; Y49-F106 HydrophobicContact CD1-CE1 4Å; Y49-F106 HydrophobicContact CD1-CZ 4.21Å; Y49-F106 HydrophobicContact CD2-CB 4.03Å; Y49-F106 AromaticContact CD2-CD1 3.54Å; Y49-F106 HydrophobicContact CD2-CD1 3.54Å; Y49-F106 HydrophobicContact CD2-CD2 4.14Å; Y49-F106 AromaticContact CD2-CE1 3.99Å; Y49-F106 HydrophobicContact CD2-CE1 3.99Å; Y49-F106 AromaticContact CD2-CG 3.62Å; Y49-F106 HydrophobicContact CD2-CG 3.62Å; Y49-F106 HydrophobicContact CD2-CZ 4.46Å; Y49-F106 HydrophobicContact CE1-CE1 4.38Å; Y49-F106 AromaticContact CE2-CD1 3.87Å; Y49-F106 HydrophobicContact CE2-CD1 3.87Å; Y49-F106 HydrophobicContact CE2-CE1 4.38Å; Y49-F106 HydrophobicContact CE2-CG 4.3Å; Y49-F106 AromaticContact CG-CD1 3.83Å; Y49-F106 HydrophobicContact CG-CD1 3.83Å; Y49-F106 HydrophobicContact CG-CD2 4.12Å; Y49-F106 AromaticContact CG-CE1 3.79Å; Y49-F106 HydrophobicContact CG-CE1 3.79Å; Y49-F106 HydrophobicContact CG-CE2 4.08Å; Y49-F106 AromaticContact CG-CG 3.99Å; Y49-F106 HydrophobicContact CG-CG 3.99Å; Y49-F106 AromaticContact CG-CZ 3.91Å; Y49-F106 HydrophobicContact CG-CZ 3.91Å; L54-F106 HydrophobicContact CB-CE2 3.79Å; L54-F106 HydrophobicContact CB-CZ 4.07Å; L54-F106 HydrophobicContact CD1-CZ 4.08Å; P55-F106 WeakPolarHBondContact O-CD2 3.32Å; Q56-F106 HydrophobicContact CB-CB 4.34Å; Q56-F106 HydrophobicContact CB-CD2 4.15Å; Q56-F106 HydrophobicContact CG-CB 4.06Å; A76-F106 HydrophobicContact CB-CD2 4.33Å; A76-F106 HydrophobicContact CB-CE2 3.86Å; A76-F106 WeakPolarHBondContact O-CD2 3.42Å; L78-F106 HydrophobicContact CG-CE1 4.25Å; L78-F106 HydrophobicContact CG-CZ 4.24Å; T104-F106 VanDerWaalsContact C-N 3.31Å; T104-F106 PolarHBondContact OG1-N 2.87Å; T104-F106 PolarHBondContact OG1-O 2.87Å; F106-T198 HydrophobicContact CD1-CG2 3.95Å; F106-T198 CarbonylContact O-C 3.45Å; F106-T198 WeakPolarHBondContact O-CA 3.29Å; F106-T198 WeakPolarHBondContact O-CB 3.2Å; F106-D199 PolarHBondContact O-N 3.25Å
107S95.8Very high95Very high12 Ų1252.2 Ų52.28%0.08424%0.243CC..  trans-108177.7178.855.40000112.4T75 A76 N77 N200T75-S107 PolarHBondContact O-OG 2.93Å; T75-S107 WeakPolarHBondContact OG1-CB 3.25Å; T75-S107 PolarHBondContact OG1-N 2.89Å; T75-S107 PolarHBondContact OG1-OG 2.82Å; A76-S107 PolarHBondContact O-N 3.02Å; A76-S107 PolarHBondContact O-OG 2.89Å; N77-S107 WeakPolarHBondContact CA-O 3.21Å; N77-S107 VanDerWaalsContact CB-O 3.31Å; N77-S107 WeakPolarHBondContact CB-O 3.44Å; S107-N200 WeakPolarHBondContact CA-OD1 3.34Å; S107-N200 WeakPolarHBondContact CB-OD1 3.47Å
108G95.4Very high95Very high0 Ų048.7 Ų48.70%023%0.225CC..SBendtrans79.8-169.1-177.100000112.1E79 W96 G110 T198 N200E79-G108 VanDerWaalsContact OE1-CA 3.29Å; E79-G108 WeakPolarHBondContact OE1-CA 3.39Å; E79-G108 WeakPolarHBondContact OE2-CA 3.14Å; W96-G108 VanDerWaalsContact CZ3-N 3.25Å; G108-G110 VanDerWaalsContact C-N 3.31Å; G108-T198 VanDerWaalsContact O-CB 3.25Å; G108-T198 WeakPolarHBondContact O-CB 3.15Å; G108-T198 PolarHBondContact O-OG1 3Å; G108-N200 PolarHBondContact N-OD1 2.97Å
109K94.4Very high95.1Very high72 Ų7242.6 Ų42.631%0.31320%0.204SC..  trans-77.5-23.1-178.8-159.417770.1164.20112.6E79 K111 L112 P113 Y115 A201E79-K109 WeakPolarHBondContact OE1-CB 3.18Å; E79-K109 PolarHBondContact OE1-N 2.62Å; K109-K111 PolarHBondContact O-N 3.08Å; K109-L112 WeakPolarHBondContact CD-O 3.44Å; K109-L112 WeakPolarHBondContact CE-O 3.44Å; K109-L112 VanDerWaalsContact CG-O 3.3Å; K109-L112 WeakPolarHBondContact CG-O 3.4Å; K109-L112 WeakPolarHBondContact O-CB 3.27Å; K109-L112 PolarHBondContact O-N 3.47Å; K109-L112 VanDerWaalsContact O-N 3.16Å; K109-P113 VanDerWaalsContact CD-O 3.3Å; K109-P113 WeakPolarHBondContact CD-O 3.42Å; K109-P113 WeakPolarHBondContact CE-O 3.34Å; K109-P113 PolarHBondContact NZ-O 3.17Å; K109-Y115 HydrophobicContact CB-CD1 4.26Å; K109-Y115 HydrophobicContact CB-CE1 3.92Å; K109-Y115 HydrophobicContact CB-CE2 4.45Å; K109-A201 HydrophobicContact CG-CB 4.3Å
110G94.1Very high95.1Very high11 Ų1142.4 Ų42.411%0.11320%0.203CC..THydrogen-bonded Turntrans58-135.4-172.900000111.1Y49 G108 L112Y49-G110 WeakPolarHBondContact OH-CA 3.4Å; G108-G110 VanDerWaalsContact C-N 3.31Å; G110-L112 VanDerWaalsContact C-N 3.35Å
111K92.8Very high95.1Very high97 Ų9734.5 Ų34.542%0.42217%0.168SC..THydrogen-bonded Turntrans-90.86.1176.4-77.6179179.2-1780113.8Y49 P50 G51 K109Y49-K111 HydrophobicContact CE1-CB 4.23Å; Y49-K111 HydrophobicContact CE1-CD 4.39Å; Y49-K111 HydrophobicContact CE1-CG 4.02Å; Y49-K111 PolarHBondContact OH-N 3.49Å; P50-K111 WeakPolarHBondContact O-CD 3.3Å; P50-K111 VanDerWaalsContact O-CE 3.26Å; P50-K111 WeakPolarHBondContact O-CE 3.31Å; P50-K111 PolarHBondContact O-NZ 2.99Å; G51-K111 VanDerWaalsContact CA-NZ 3.27Å; G51-K111 PolarHBondContact O-NZ 3.29Å; K109-K111 PolarHBondContact O-N 3.08Å
112L95Very high95.3Very high4 Ų432.7 Ų32.72%0.02116%0.161CC..SBendtrans-80.9152.3178.2-62.6-179.8000111.1K109 G110 Q196 A201 L203K109-L112 WeakPolarHBondContact CD-O 3.44Å; K109-L112 WeakPolarHBondContact CE-O 3.44Å; K109-L112 VanDerWaalsContact CG-O 3.3Å; K109-L112 WeakPolarHBondContact CG-O 3.4Å; K109-L112 WeakPolarHBondContact O-CB 3.27Å; K109-L112 PolarHBondContact O-N 3.47Å; K109-L112 VanDerWaalsContact O-N 3.16Å; G110-L112 VanDerWaalsContact C-N 3.35Å; L112-Q196 HydrophobicContact CD2-CB 4.25Å; L112-A201 HydrophobicContact CB-CB 4.08Å; L112-A201 VanDerWaalsContact CD1-C 3.47Å; L112-A201 HydrophobicContact CD1-CB 3.81Å; L112-A201 WeakPolarHBondContact CD1-O 3.38Å; L112-A201 HydrophobicContact CG-CB 4.49Å; L112-L203 HydrophobicContact CD1-CD2 4.44Å; L112-L203 HydrophobicContact CD2-CD2 3.71Å
113P92.9Very high95.4Very high76 Ų7632.1 Ų32.149%0.49416%0.159SC..SBendtrans-60.3-42.6-180-28.133.9000114.8K109 N118K109-P113 VanDerWaalsContact CD-O 3.3Å; K109-P113 WeakPolarHBondContact CD-O 3.42Å; K109-P113 WeakPolarHBondContact CE-O 3.34Å; K109-P113 PolarHBondContact NZ-O 3.17Å; P113-N118 WeakPolarHBondContact CD-OD1 3.31Å
114E93.9Very high95.4Very high129 Ų12930.4 Ų30.460%0.60315%0.152SC*.SBendtrans-133.9154.2-168.3-67172.9-162.700112.2N118 A201E114-N118 PolarHBondContact N-OD1 2.95Å; E114-N118 PolarHBondContact O-ND2 3.11Å; E114-A201 VanDerWaalsContact O-CB 3.27Å; E114-A201 WeakPolarHBondContact O-CB 3.45Å
115Y95.2Very high95.4Very high79 Ų7929.8 Ų29.831%0.3115%0.149SC..SBendtrans-68.2146.4165.4-70.9-77.9000109.6E79 W96 K109 N200E79-Y115 PolarHBondContact OE1-OH 3.07Å; W96-Y115 AromaticContact CD1-CE1 3.92Å; W96-Y115 AromaticContact CD1-CZ 3.9Å; W96-Y115 AromaticContact CD2-CE1 3.97Å; W96-Y115 HydrophobicContact CD2-CE1 3.97Å; W96-Y115 AromaticContact CE2-CE1 3.95Å; W96-Y115 AromaticContact CE2-CZ 3.91Å; W96-Y115 HydrophobicContact CG-CD1 4.48Å; W96-Y115 AromaticContact CG-CE1 3.95Å; W96-Y115 HydrophobicContact CG-CE1 3.95Å; W96-Y115 AromaticContact NE1-CE1 3.93Å; W96-Y115 AromaticContact NE1-CZ 3.61Å; W96-Y115 PolarHBondContact NE1-OH 2.76Å; K109-Y115 HydrophobicContact CB-CD1 4.26Å; K109-Y115 HydrophobicContact CB-CE1 3.92Å; K109-Y115 HydrophobicContact CB-CE2 4.45Å; Y115-N200 CarbonylContact C-O 3.58Å; Y115-N200 HydrophobicContact CD1-CB 3.85Å; Y115-N200 HydrophobicContact CE1-CB 4.19Å
116G95.7Very high95.4Very high0 Ų030 Ų300%015%0.149CC..EExtended strand (participates in β ladder)trans82-151.2-176.700000113.5N118 N200 A201 W202G116-N118 PolarHBondContact O-ND2 3Å; G116-N200 PolarHBondContact N-O 3.18Å; G116-A201 WeakPolarHBondContact O-CA 3.38Å; G116-W202 PolarHBondContact O-N 3.4Å
117P94.9Very high95.3Very high54 Ų5430.6 Ų30.635%0.35115%0.154SC..EExtended strand (participates in β ladder)trans-67.9129.6-178.7-19.431.7000113.3W202 E204P117-W202 CarbonylContact C-O 3.59Å; P117-W202 HydrophobicContact CG-CZ2 3.67Å; P117-E204 HydrophobicContact CB-CB 3.96Å; P117-E204 WeakPolarHBondContact CB-OE2 3.49Å; P117-E204 WeakPolarHBondContact CG-OE2 3.36Å
118N96Very high95.1Very high12 Ų1237 Ų376%0.06418%0.177CC..EExtended strand (participates in β ladder)trans-115.6123.2172.9-70.8-102.7000108.9P113 E114 G116 A120 W202 L203 E204P113-N118 WeakPolarHBondContact CD-OD1 3.31Å; E114-N118 PolarHBondContact N-OD1 2.95Å; E114-N118 PolarHBondContact O-ND2 3.11Å; G116-N118 PolarHBondContact O-ND2 3Å; N118-A120 PolarHBondContact O-N 3.47Å; N118-W202 PolarHBondContact N-O 3.45Å; N118-L203 HydrophobicContact CB-CD2 4.02Å; N118-L203 WeakPolarHBondContact O-CA 3.42Å; N118-E204 PolarHBondContact O-N 3.41Å
119K95.4Very high94.7Very high75 Ų7539.3 Ų39.333%0.32619%0.194SC..EExtended strand (participates in β ladder)trans-71.9129-171.5-66.6-59.4-174.7-1770112.8V151 E204K119-V151 VanDerWaalsContact CB-O 3.24Å; K119-V151 WeakPolarHBondContact CB-O 3.5Å; K119-V151 PolarHBondContact O-N 3.26Å; K119-V151 VanDerWaalsContact O-O 3.09Å; K119-E204 VanDerWaalsContact CA-O 3.28Å; K119-E204 WeakPolarHBondContact CA-O 3.27Å; K119-E204 IonicContact NZ-OE1 3.96Å; K119-E204 PolarHBondContact NZ-OE1 3.39Å
120A95.8Very high94.2Very high0 Ų041.3 Ų41.30%022%0.217CC..EExtended strand (participates in β ladder)trans-141.3157.9177.700000111.6N118 F149 L192 L203 E204 G205N118-A120 PolarHBondContact O-N 3.47Å; A120-F149 CarbonylContact C-O 3.37Å; A120-F149 VanDerWaalsContact CA-O 3.3Å; A120-F149 WeakPolarHBondContact CA-O 3.43Å; A120-L192 HydrophobicContact CB-CD1 4.05Å; A120-L203 HydrophobicContact CB-CB 4.31Å; A120-L203 HydrophobicContact CB-CD1 4.06Å; A120-L203 HydrophobicContact CB-CD2 4.25Å; A120-L203 HydrophobicContact CB-CG 4.45Å; A120-E204 PolarHBondContact N-O 3.06Å; A120-G205 WeakPolarHBondContact O-CA 3.45Å
121L96.2Very high93.9Very high0 Ų042.9 Ų42.90%023%0.233CC..EExtended strand (participates in β ladder)trans-118122.4173.917159.5000108.5L123 R148 F149 V151 I156 I161 K164 P206 I208L121-L123 HydrophobicContact CD1-CD2 3.86Å; L121-L123 HydrophobicContact CD2-CD2 3.91Å; L121-L123 HydrophobicContact CD2-CG 4.49Å; L121-L123 HydrophobicContact CG-CD2 3.82Å; L121-L123 HydrophobicContact CG-CG 4.29Å; L121-R148 CarbonylContact O-C 3.57Å; L121-R148 VanDerWaalsContact O-CA 3.31Å; L121-R148 WeakPolarHBondContact O-CA 3.23Å; L121-F149 PolarHBondContact N-O 2.84Å; L121-F149 PolarHBondContact O-N 2.76Å; L121-V151 HydrophobicContact CB-CG2 3.99Å; L121-I156 HydrophobicContact CB-CD1 3.93Å; L121-I156 HydrophobicContact CD1-CG2 4.25Å; L121-I156 HydrophobicContact CD2-CG2 4.15Å; L121-I161 HydrophobicContact CD2-CG1 4.1Å; L121-K164 HydrophobicContact CD2-CB 4.2Å; L121-K164 HydrophobicContact CD2-CG 4.04Å; L121-P206 HydrophobicContact CD1-CG 4Å; L121-I208 HydrophobicContact CD1-CB 4.15Å; L121-I208 HydrophobicContact CD1-CG1 3.61Å
122Y97.2Very high93.9Very high4 Ų439.7 Ų39.72%0.01622%0.222CC..EExtended strand (participates in β ladder)trans-100.5134.5168.1-78.215.4000109.1P147 R148 L192 K193 N194 L203 P206 I207 I208 F251Y122-P147 WeakPolarHBondContact CA-O 3.45Å; Y122-R148 HydrophobicContact CD1-CB 3.4Å; Y122-R148 HydrophobicContact CE1-CB 3.37Å; Y122-R148 HydrophobicContact CE1-CG 4.32Å; Y122-R148 HydrophobicContact CG-CB 4.36Å; Y122-L192 HydrophobicContact CD1-CD1 3.92Å; Y122-L192 HydrophobicContact CD2-CB 4.44Å; Y122-L192 HydrophobicContact CD2-CD1 4.49Å; Y122-L192 HydrophobicContact CD2-CD2 3.94Å; Y122-L192 HydrophobicContact CE1-CB 4.41Å; Y122-L192 HydrophobicContact CE1-CD1 4.09Å; Y122-L192 HydrophobicContact CE2-CB 4Å; Y122-L192 HydrophobicContact CE2-CD2 4.32Å; Y122-L192 HydrophobicContact CG-CD1 4.14Å; Y122-L192 HydrophobicContact CG-CD2 4.18Å; Y122-K193 PolarHBondContact OH-O 3.04Å; Y122-N194 WeakPolarHBondContact OH-CB 3.43Å; Y122-N194 PolarHBondContact OH-ND2 3.29Å; Y122-L203 HydrophobicContact CE1-CD1 4.15Å; Y122-P206 PolarHBondContact N-O 3.15Å; Y122-I207 HydrophobicContact CD2-CG1 4.44Å; Y122-I207 WeakPolarHBondContact O-CA 3.44Å; Y122-I208 PolarHBondContact O-N 3.14Å; Y122-F251 HydrophobicContact CD2-CB 4.23Å; Y122-F251 HydrophobicContact CE2-CB 4.36Å
123L97.4Very high93.8Very high0 Ų041.4 Ų41.40%023%0.232CC..EExtended strand (participates in β ladder)trans-110.3123.5176.4-60.7-176.6000109.7L121 I125 P147 F149 I161 V165 L168 I208 L210L121-L123 HydrophobicContact CD1-CD2 3.86Å; L121-L123 HydrophobicContact CD2-CD2 3.91Å; L121-L123 HydrophobicContact CD2-CG 4.49Å; L121-L123 HydrophobicContact CG-CD2 3.82Å; L121-L123 HydrophobicContact CG-CG 4.29Å; L123-I125 HydrophobicContact CB-CD1 4.33Å; L123-I125 HydrophobicContact CB-CG1 4.07Å; L123-I125 HydrophobicContact CD1-CD1 4.31Å; L123-P147 HydrophobicContact CB-CB 4.38Å; L123-P147 PolarHBondContact N-O 2.93Å; L123-P147 WeakPolarHBondContact O-CD 3.35Å; L123-F149 HydrophobicContact CD1-CD2 4.27Å; L123-F149 HydrophobicContact CD1-CE2 3.63Å; L123-F149 HydrophobicContact CD1-CZ 4.49Å; L123-F149 HydrophobicContact CG-CD2 4.38Å; L123-F149 HydrophobicContact CG-CE2 4.07Å; L123-I161 HydrophobicContact CD2-CG2 4.41Å; L123-V165 HydrophobicContact CD1-CG2 3.81Å; L123-L168 HydrophobicContact CD1-CD1 4.32Å; L123-I208 WeakPolarHBondContact CA-O 3.3Å; L123-I208 HydrophobicContact CD2-CB 4.13Å; L123-L210 HydrophobicContact CD1-CD1 4.39Å; L123-L210 HydrophobicContact CD2-CD1 4.15Å
124L97.4Very high93.9Very high1 Ų141 Ų411%0.00522%0.222CC..EExtended strand (participates in β ladder)trans-97.5103.2162.2176.963.3000107.7T126 F135 L146 Y187 I208 H209 L210 P244 F247 A248L124-T126 HydrophobicContact CD1-CG2 4.28Å; L124-T126 HydrophobicContact CD2-CG2 4.47Å; L124-T126 HydrophobicContact CG-CG2 4.06Å; L124-F135 HydrophobicContact CD1-CB 3.92Å; L124-F135 HydrophobicContact CD1-CD2 4.11Å; L124-F135 HydrophobicContact CD1-CG 4.32Å; L124-L146 HydrophobicContact CB-CD1 4.4Å; L124-L146 HydrophobicContact CD1-CD2 3.82Å; L124-Y187 HydrophobicContact CD2-CD2 4.21Å; L124-Y187 HydrophobicContact CD2-CE2 4.16Å; L124-I208 PolarHBondContact N-O 3.16Å; L124-H209 CarbonylContact O-C 3.38Å; L124-H209 VanDerWaalsContact O-CA 3.3Å; L124-H209 WeakPolarHBondContact O-CA 3.32Å; L124-H209 PolarHBondContact O-CD2 2.68Å; L124-H209 VanDerWaalsContact O-CD2 3.31Å; L124-L210 PolarHBondContact O-N 3.43Å; L124-P244 HydrophobicContact CD2-CB 3.9Å; L124-P244 WeakPolarHBondContact CD2-O 3.17Å; L124-F247 HydrophobicContact CD1-CD1 4.16Å; L124-F247 HydrophobicContact CD1-CE1 4.4Å; L124-A248 HydrophobicContact CD2-CB 4.06Å
125I96.3Very high93.9Very high0 Ų035.1 Ų35.10%020%0.195CC..EExtended strand (participates in β ladder)trans-101120.2178.5-55.6175.2000107.7L123 F135 I136 L168 L210 F219 W235L123-I125 HydrophobicContact CB-CD1 4.33Å; L123-I125 HydrophobicContact CB-CG1 4.07Å; L123-I125 HydrophobicContact CD1-CD1 4.31Å; I125-F135 CarbonylContact O-C 3.58Å; I125-F135 WeakPolarHBondContact O-CA 3.24Å; I125-I136 HydrophobicContact CB-CB 4.36Å; I125-I136 HydrophobicContact CB-CD1 3.86Å; I125-I136 HydrophobicContact CB-CG1 4.16Å; I125-I136 HydrophobicContact CD1-CD1 4.14Å; I125-I136 HydrophobicContact CG2-CD1 3.72Å; I125-I136 HydrophobicContact CG2-CG1 4.3Å; I125-I136 PolarHBondContact O-N 3.08Å; I125-L168 HydrophobicContact CD1-CD1 3.76Å; I125-L210 CarbonylContact C-O 3.55Å; I125-L210 WeakPolarHBondContact CA-O 3.3Å; I125-L210 HydrophobicContact CG1-CB 4.38Å; I125-L210 HydrophobicContact CG1-CD1 4.35Å; I125-F219 HydrophobicContact CD1-CE1 3.95Å; I125-F219 HydrophobicContact CD1-CZ 3.9Å; I125-F219 HydrophobicContact CG2-CD2 4.06Å; I125-F219 HydrophobicContact CG2-CE2 3.59Å; I125-F219 HydrophobicContact CG2-CZ 3.94Å; I125-W235 HydrophobicContact CG2-CH2 4.32Å
126T95.8Very high93.8Very high3 Ų331.4 Ų31.42%0.01818%0.18CC..EExtended strand (participates in β ladder)trans-116.3153.5178.966.80000112L124 T133 K134 F135 H209 L210 H211 D212 P244L124-T126 HydrophobicContact CD1-CG2 4.28Å; L124-T126 HydrophobicContact CD2-CG2 4.47Å; L124-T126 HydrophobicContact CG-CG2 4.06Å; T126-T133 HydrophobicContact CG2-CG2 4.4Å; T126-K134 CarbonylContact C-O 3.52Å; T126-K134 WeakPolarHBondContact CA-O 3.24Å; T126-K134 WeakPolarHBondContact CB-O 3.45Å; T126-F135 HydrophobicContact CG2-CB 4.1Å; T126-H209 PolarHBondContact OG1-NE2 3.25Å; T126-L210 PolarHBondContact N-O 3.29Å; T126-H211 CarbonylContact O-C 3.5Å; T126-H211 WeakPolarHBondContact O-CA 3.46Å; T126-H211 PolarHBondContact O-ND1 2.96Å; T126-H211 PolarHBondContact OG1-ND1 2.83Å; T126-D212 PolarHBondContact O-N 3.39Å; T126-P244 HydrophobicContact CG2-CB 4.31Å; T126-P244 HydrophobicContact CG2-CG 4.39Å
127S94.1Very high93.7Very high14 Ų1431.5 Ų31.510%0.09818%0.181CC..EExtended strand (participates in β ladder)trans-137.5146.8169.8175.80000108.4K134 W235S127-K134 PolarHBondContact N-O 3.24Å; S127-K134 PolarHBondContact O-N 3.42Å; S127-W235 VanDerWaalsContact CB-CH2 3.48Å
128Y91.1Very high93.5Very high145 Ų14529.9 Ų29.957%0.56917%0.169SC*.EExtended strand (participates in β ladder)trans-108.5120.4176-175.6-101.5000109.2G131Y128-G131 WeakPolarHBondContact OH-CA 3.48Å
129S86.7Confident92.8Very high49 Ų4932.6 Ų32.634%0.34318%0.183SC..EExtended strand (participates in β ladder)trans-150.4135.8-178.1-179.10000110.2G131 T132S129-G131 VanDerWaalsContact C-N 3.31Å; S129-G131 PolarHBondContact O-N 2.84Å; S129-T132 PolarHBondContact N-O 3.04Å; S129-T132 PolarHBondContact O-N 2.83Å; S129-T132 VanDerWaalsContact O-O 3.12Å; S129-T132 PolarHBondContact O-OG1 3.17Å
130S85.1Confident91.8Very high115 Ų11530.1 Ų30.180%0.80418%0.175SC*.THydrogen-bonded Turntrans51.344.8177.8-52.70000113.7T132S130-T132 PolarHBondContact O-N 2.97Å
131G87.4Confident90.5Very high43 Ų4336.8 Ų36.844%0.44322%0.215SC..THydrogen-bonded Turntrans80.1-3.6178.400000115.2Y128 S129Y128-G131 WeakPolarHBondContact OH-CA 3.48Å; S129-G131 VanDerWaalsContact C-N 3.31Å; S129-G131 PolarHBondContact O-N 2.84Å
132T91.7Very high89.3Confident31 Ų3141.9 Ų41.919%0.1924%0.242CC..EExtended strand (participates in β ladder)trans-119.7138-174.263.70000111.9S129 S130 K134 V237S129-T132 PolarHBondContact N-O 3.04Å; S129-T132 PolarHBondContact O-N 2.83Å; S129-T132 VanDerWaalsContact O-O 3.12Å; S129-T132 PolarHBondContact O-OG1 3.17Å; S130-T132 PolarHBondContact O-N 2.97Å; T132-K134 WeakPolarHBondContact OG1-CE 3.13Å; T132-V237 HydrophobicContact CG2-CG1 4.47Å
133T94.1Very high88.4Confident39 Ų3945.3 Ų45.324%0.23926%0.256CS..EExtended strand (participates in β ladder)trans-85123167.4-57.70000108.6T126 L238T126-T133 HydrophobicContact CG2-CG2 4.4Å; T133-L238 HydrophobicContact CG2-CB 4.43Å; T133-L238 HydrophobicContact CG2-CD2 4.28Å; T133-L238 WeakPolarHBondContact O-CB 3.37Å; T133-L238 PolarHBondContact O-N 2.94Å
134K94.1Very high87.8Confident67 Ų6749.6 Ų49.629%0.29128%0.278SS..EExtended strand (participates in β ladder)trans-109.5156.9174.4-59.2177.5-173.1170.80109.9T126 S127 T132 W235 R236 V237T126-K134 CarbonylContact C-O 3.52Å; T126-K134 WeakPolarHBondContact CA-O 3.24Å; T126-K134 WeakPolarHBondContact CB-O 3.45Å; S127-K134 PolarHBondContact N-O 3.24Å; S127-K134 PolarHBondContact O-N 3.42Å; T132-K134 WeakPolarHBondContact OG1-CE 3.13Å; K134-W235 HydrophobicContact CB-CB 4.41Å; K134-W235 HydrophobicContact CB-CD2 4.44Å; K134-W235 HydrophobicContact CB-CE3 3.66Å; K134-W235 HydrophobicContact CB-CZ3 4.33Å; K134-R236 CarbonylContact C-O 3.51Å; K134-R236 WeakPolarHBondContact CA-O 3.4Å; K134-V237 HydrophobicContact CG-CG2 4.23Å
135F94.3Very high87.5Confident7 Ų749.8 Ų49.83%0.03128%0.28CS..EExtended strand (participates in β ladder)trans-140.2151.817668.4-75000112.2L124 I125 T126 V137 I144 W235 R236 L238 F247L124-F135 HydrophobicContact CD1-CB 3.92Å; L124-F135 HydrophobicContact CD1-CD2 4.11Å; L124-F135 HydrophobicContact CD1-CG 4.32Å; I125-F135 CarbonylContact O-C 3.58Å; I125-F135 WeakPolarHBondContact O-CA 3.24Å; T126-F135 HydrophobicContact CG2-CB 4.1Å; F135-V137 HydrophobicContact CD2-CG1 3.4Å; F135-V137 HydrophobicContact CE2-CG1 3Å; F135-V137 HydrophobicContact CZ-CG1 3.86Å; F135-I144 HydrophobicContact CE2-CG2 4.45Å; F135-W235 CarbonylContact O-C 3.58Å; F135-W235 WeakPolarHBondContact O-CA 3.05Å; F135-R236 HydrophobicContact CD1-CB 4.26Å; F135-R236 WeakPolarHBondContact CD1-O 3.12Å; F135-R236 HydrophobicContact CE1-CB 3.71Å; F135-R236 HydrophobicContact CZ-CB 3.86Å; F135-R236 PolarHBondContact N-O 3Å; F135-R236 PolarHBondContact O-N 2.74Å; F135-L238 HydrophobicContact CD1-CB 4.01Å; F135-L238 HydrophobicContact CD1-CD1 4.19Å; F135-L238 HydrophobicContact CE1-CB 4.28Å; F135-L238 HydrophobicContact CE1-CD1 4.09Å; F135-F247 HydrophobicContact CD2-CD1 4.41Å; F135-F247 AromaticContact CD2-CE1 3.64Å; F135-F247 HydrophobicContact CD2-CE1 3.64Å; F135-F247 HydrophobicContact CD2-CZ 4.21Å; F135-F247 HydrophobicContact CE1-CE1 4.47Å; F135-F247 HydrophobicContact CE1-CZ 4.4Å; F135-F247 HydrophobicContact CE2-CD1 4.19Å; F135-F247 AromaticContact CE2-CE1 3.15Å; F135-F247 HydrophobicContact CE2-CE1 3.15Å; F135-F247 HydrophobicContact CE2-CE2 4.35Å; F135-F247 AromaticContact CE2-CZ 3.26Å; F135-F247 HydrophobicContact CE2-CZ 3.26Å; F135-F247 HydrophobicContact CG-CE1 4.45Å; F135-F247 AromaticContact CZ-CE1 3.66Å; F135-F247 HydrophobicContact CZ-CE1 3.66Å; F135-F247 HydrophobicContact CZ-CE2 4.1Å; F135-F247 AromaticContact CZ-CZ 3.4Å; F135-F247 HydrophobicContact CZ-CZ 3.4Å
136I94Very high87.4Confident0 Ų049.9 Ų49.90%028%0.28CS..EExtended strand (participates in β ladder)trans-82.4130.4179.7-59.6179.7000110.1I125 P147 F219 P223 Y233 W235I125-I136 HydrophobicContact CB-CB 4.36Å; I125-I136 HydrophobicContact CB-CD1 3.86Å; I125-I136 HydrophobicContact CB-CG1 4.16Å; I125-I136 HydrophobicContact CD1-CD1 4.14Å; I125-I136 HydrophobicContact CG2-CD1 3.72Å; I125-I136 HydrophobicContact CG2-CG1 4.3Å; I125-I136 PolarHBondContact O-N 3.08Å; I136-P147 HydrophobicContact CB-CG 4.37Å; I136-P147 HydrophobicContact CG2-CG 3.88Å; I136-P147 WeakPolarHBondContact O-CD 3.42Å; I136-F219 HydrophobicContact CD1-CB 3.99Å; I136-F219 HydrophobicContact CD1-CD1 4.05Å; I136-F219 HydrophobicContact CD1-CD2 4.22Å; I136-F219 HydrophobicContact CD1-CG 3.82Å; I136-P223 HydrophobicContact CD1-CG 3.96Å; I136-P223 HydrophobicContact CG1-CG 4.46Å; I136-P223 HydrophobicContact CG2-CG 4.37Å; I136-Y233 HydrophobicContact CG2-CD1 3.84Å; I136-Y233 HydrophobicContact CG2-CG 4.05Å; I136-W235 HydrophobicContact CD1-CH2 3.91Å; I136-W235 HydrophobicContact CD1-CZ2 3.72Å; I136-W235 HydrophobicContact CD1-CZ3 4.48Å; I136-W235 HydrophobicContact CG1-CD2 3.87Å; I136-W235 HydrophobicContact CG1-CE3 3.84Å; I136-W235 HydrophobicContact CG1-CH2 3.66Å; I136-W235 HydrophobicContact CG1-CZ2 3.66Å; I136-W235 HydrophobicContact CG1-CZ3 3.73Å
137V92.9Very high87.4Confident3 Ų349.7 Ų49.72%0.01828%0.279CS..EExtended strand (participates in β ladder)trans-130.2148.2173.8-59.10000111.7F135 D139 I144 A145 Y233 R234 R236F135-V137 HydrophobicContact CD2-CG1 3.4Å; F135-V137 HydrophobicContact CE2-CG1 3Å; F135-V137 HydrophobicContact CZ-CG1 3.86Å; V137-D139 PolarHBondContact O-N 3.15Å; V137-I144 HydrophobicContact CB-CG2 4.06Å; V137-I144 HydrophobicContact CG1-CG2 3.58Å; V137-A145 CarbonylContact C-O 3.53Å; V137-A145 WeakPolarHBondContact CA-O 3.28Å; V137-Y233 VanDerWaalsContact C-CD1 3.49Å; V137-Y233 WeakPolarHBondContact O-CA 3.29Å; V137-Y233 WeakPolarHBondContact O-CD1 3.48Å; V137-R234 HydrophobicContact CG2-CG 4.01Å; V137-R234 PolarHBondContact N-O 2.92Å; V137-R234 PolarHBondContact O-N 2.86Å; V137-R236 HydrophobicContact CG1-CG 4.42Å; V137-R236 HydrophobicContact CG2-CB 4.4Å; V137-R236 HydrophobicContact CG2-CG 3.5Å; V137-R236 VanDerWaalsContact CG2-CG 3.5Å
138E90.1Very high87.3Confident19 Ų1949.8 Ų49.89%0.08928%0.277CS..EExtended strand (participates in β ladder)trans-68.4124.7167.6-167.3-179.4167.400108.6T140 A145 R148 R231 R232 Y233E138-T140 HydrophobicContact CB-CG2 4.35Å; E138-T140 HydrophobicContact CG-CG2 3.94Å; E138-T140 PolarHBondContact O-N 3.28Å; E138-A145 HydrophobicContact CB-CB 4.13Å; E138-A145 PolarHBondContact N-O 2.67Å; E138-R148 IonicContact OE1-NH2 3.78Å; E138-R148 IonicContact OE2-CZ 2.73Å; E138-R148 IonicContact OE2-NE 3.04Å; E138-R148 PolarHBondContact OE2-NE 3.25Å; E138-R148 VanDerWaalsContact OE2-NE 3.11Å; E138-R148 IonicContact OE2-NH2 3.31Å; E138-R148 PolarHBondContact OE2-NH2 3.41Å; E138-R231 WeakPolarHBondContact OE1-CG 3.3Å; E138-R231 IonicContact OE1-NE 3.61Å; E138-R232 CarbonylContact C-O 3.43Å; E138-R232 WeakPolarHBondContact CA-O 3.18Å; E138-Y233 HydrophobicContact CB-CD1 4.05Å; E138-Y233 HydrophobicContact CB-CE1 3.65Å; E138-Y233 HydrophobicContact CG-CE1 4.12Å
139D81.5Confident87.4Confident69 Ų6943.2 Ų43.237%0.36925%0.252SS..EExtended strand (participates in β ladder)trans-75.6104.6177.4-168.48.2000109.9V137 R232 R234V137-D139 PolarHBondContact O-N 3.15Å; D139-R232 HydrophobicContact CB-CB 4.32Å; D139-R232 PolarHBondContact N-O 2.89Å; D139-R234 HydrophobicContact CB-CG 4.39Å; D139-R234 VanDerWaalsContact CG-CZ 3.4Å; D139-R234 IonicContact OD1-CZ 2.67Å; D139-R234 IonicContact OD1-NE 3.8Å; D139-R234 PolarHBondContact OD1-NE 2.8Å; D139-R234 IonicContact OD1-NH1 3.48Å; D139-R234 IonicContact OD1-NH2 3.92Å; D139-R234 PolarHBondContact OD1-NH2 2.82Å; D139-R234 IonicContact OD2-CZ 3.82Å; D139-R234 IonicContact OD2-NE 3.05Å; D139-R234 IonicContact OD2-NH1 2.62Å; D139-R234 IonicContact OD2-NH2 3.39Å
140T75.5Confident87.7Confident23 Ų2344.7 Ų44.714%0.14125%0.25CC..EExtended strand (participates in β ladder)trans-128.1142.7173.485.20000108.8E138 N142 Y143E138-T140 HydrophobicContact CB-CG2 4.35Å; E138-T140 HydrophobicContact CG-CG2 3.94Å; E138-T140 PolarHBondContact O-N 3.28Å; T140-N142 PolarHBondContact O-N 3.42Å; T140-N142 VanDerWaalsContact O-N 3.08Å; T140-Y143 HydrophobicContact CG2-CD1 4.45Å; T140-Y143 HydrophobicContact CG2-CE1 3.87Å; T140-Y143 HydrophobicContact CG2-CE2 4.02Å; T140-Y143 WeakPolarHBondContact OG1-CD1 3.11Å; T140-Y143 WeakPolarHBondContact OG1-CE1 2.91Å; T140-Y143 PolarHBondContact OG1-N 2.91Å; T140-Y143 PolarHBondContact OG1-O 3.5Å
141V66.7Low88Confident140 Ų14039.8 Ų39.885%0.84822%0.215SC*.THydrogen-bonded Turntrans-57.1-31.8-172.4-176.10000112.5
142N72Confident87.9Confident108 Ų10848.2 Ų48.258%0.57824%0.239SC*.THydrogen-bonded Turntrans-124.61.8-165.2-63.9-32.5000114.7T140T140-N142 PolarHBondContact O-N 3.42Å; T140-N142 VanDerWaalsContact O-N 3.08Å
143Y78.6Confident87.3Confident75 Ų7552 Ų5229%0.29425%0.253SS..EExtended strand (participates in β ladder)trans-159.9163.3179.665.3-77.8000113.3T140 A145 R148 R195T140-Y143 HydrophobicContact CG2-CD1 4.45Å; T140-Y143 HydrophobicContact CG2-CE1 3.87Å; T140-Y143 HydrophobicContact CG2-CE2 4.02Å; T140-Y143 WeakPolarHBondContact OG1-CD1 3.11Å; T140-Y143 WeakPolarHBondContact OG1-CE1 2.91Å; T140-Y143 PolarHBondContact OG1-N 2.91Å; T140-Y143 PolarHBondContact OG1-O 3.5Å; Y143-A145 HydrophobicContact CD2-CB 4Å; Y143-A145 HydrophobicContact CE2-CB 3.68Å; Y143-R148 PolarHBondContact OH-NH2 3.36Å; Y143-R195 VanDerWaalsContact CD1-NH2 3.3Å
144I84.6Confident86.5Confident90 Ų9054.2 Ų54.246%0.46228%0.275SS..EExtended strand (participates in β ladder)trans-98.6132.3170.2-60.3175.3000107.7F135 V137 F247 F251F135-I144 HydrophobicContact CE2-CG2 4.45Å; V137-I144 HydrophobicContact CB-CG2 4.06Å; V137-I144 HydrophobicContact CG1-CG2 3.58Å; I144-F247 HydrophobicContact CG2-CZ 4.44Å; I144-F251 HydrophobicContact CG2-CZ 4.13Å
145A91Very high86Confident6 Ų656 Ų565%0.0529%0.292CS..EExtended strand (participates in β ladder)trans-132.3142.7170.600000110.8V137 E138 Y143V137-A145 CarbonylContact C-O 3.53Å; V137-A145 WeakPolarHBondContact CA-O 3.28Å; E138-A145 HydrophobicContact CB-CB 4.13Å; E138-A145 PolarHBondContact N-O 2.67Å; Y143-A145 HydrophobicContact CD2-CB 4Å; Y143-A145 HydrophobicContact CE2-CB 3.68Å
146L94.5Very high85.8Confident1 Ų157.5 Ų57.51%0.00530%0.3CS..  trans-73.3150.1168.5-62.6-178.2000110.1L124 R148 I207 F247 F251L124-L146 HydrophobicContact CB-CD1 4.4Å; L124-L146 HydrophobicContact CD1-CD2 3.82Å; L146-R148 WeakPolarHBondContact O-CG 3.44Å; L146-R148 PolarHBondContact O-N 2.97Å; L146-I207 HydrophobicContact CD1-CG2 4.01Å; L146-F247 HydrophobicContact CD2-CE1 4.22Å; L146-F251 HydrophobicContact CD1-CB 4.26Å; L146-F251 HydrophobicContact CD1-CD1 4.41Å; L146-F251 HydrophobicContact CD1-CD2 3.67Å; L146-F251 HydrophobicContact CD1-CE2 4.1Å; L146-F251 HydrophobicContact CD1-CG 3.85Å; L146-F251 HydrophobicContact CD2-CD2 4.5Å; L146-F251 HydrophobicContact CD2-CE2 4.09Å; L146-F251 HydrophobicContact CD2-CZ 4.21Å; L146-F251 HydrophobicContact CG-CD1 4.1Å; L146-F251 HydrophobicContact CG-CD2 3.91Å; L146-F251 HydrophobicContact CG-CE1 4.08Å; L146-F251 HydrophobicContact CG-CE2 3.9Å; L146-F251 HydrophobicContact CG-CG 4.01Å; L146-F251 HydrophobicContact CG-CZ 3.99Å
147P94.6Very high85.7Confident0 Ų060.4 Ų60.40%032%0.316CS..  trans-50.1132.2164.3-21.226.1000111.5Y122 L123 I136 F149 L168 Y233Y122-P147 WeakPolarHBondContact CA-O 3.45Å; L123-P147 HydrophobicContact CB-CB 4.38Å; L123-P147 PolarHBondContact N-O 2.93Å; L123-P147 WeakPolarHBondContact O-CD 3.35Å; I136-P147 HydrophobicContact CB-CG 4.37Å; I136-P147 HydrophobicContact CG2-CG 3.88Å; I136-P147 WeakPolarHBondContact O-CD 3.42Å; P147-F149 HydrophobicContact CB-CE2 4.31Å; P147-L168 HydrophobicContact CB-CD1 3.5Å; P147-L168 HydrophobicContact CB-CD2 4.35Å; P147-L168 HydrophobicContact CG-CD1 3.96Å; P147-Y233 HydrophobicContact CB-CD1 4.48Å; P147-Y233 HydrophobicContact CB-CE1 3.81Å; P147-Y233 HydrophobicContact CG-CD1 3.9Å; P147-Y233 HydrophobicContact CG-CE1 3.68Å
148R93.1Very high85.8Confident15 Ų1561.4 Ų61.46%0.05732%0.324CS..EExtended strand (participates in β ladder)trans-145.4135.6-165.752.2-178.9156.6172.4-3.3112.1L121 Y122 E138 Y143 L146 W150 N194 R231L121-R148 CarbonylContact O-C 3.57Å; L121-R148 VanDerWaalsContact O-CA 3.31Å; L121-R148 WeakPolarHBondContact O-CA 3.23Å; Y122-R148 HydrophobicContact CD1-CB 3.4Å; Y122-R148 HydrophobicContact CE1-CB 3.37Å; Y122-R148 HydrophobicContact CE1-CG 4.32Å; Y122-R148 HydrophobicContact CG-CB 4.36Å; E138-R148 IonicContact OE1-NH2 3.78Å; E138-R148 IonicContact OE2-CZ 2.73Å; E138-R148 IonicContact OE2-NE 3.04Å; E138-R148 PolarHBondContact OE2-NE 3.25Å; E138-R148 VanDerWaalsContact OE2-NE 3.11Å; E138-R148 IonicContact OE2-NH2 3.31Å; E138-R148 PolarHBondContact OE2-NH2 3.41Å; Y143-R148 PolarHBondContact OH-NH2 3.36Å; L146-R148 WeakPolarHBondContact O-CG 3.44Å; L146-R148 PolarHBondContact O-N 2.97Å; R148-W150 HydrophobicContact CB-CZ3 3.81Å; R148-W150 HydrophobicContact CG-CH2 4.05Å; R148-W150 HydrophobicContact CG-CZ3 3.65Å; R148-N194 PolarHBondContact NH1-ND2 2.74Å; R148-N194 PolarHBondContact NH1-OD1 2.76Å; R148-R231 PolarHBondContact O-NH1 2.87Å; R148-R231 VanDerWaalsContact O-NH1 3.17Å
149F93.8Very high86Confident7 Ų763.4 Ų63.43%0.03134%0.335CS..EExtended strand (participates in β ladder)trans-134.8132.2-172.2-57.4-87.2000111.8A120 L121 L123 P147 K164 K167 L168 H225A120-F149 CarbonylContact C-O 3.37Å; A120-F149 VanDerWaalsContact CA-O 3.3Å; A120-F149 WeakPolarHBondContact CA-O 3.43Å; L121-F149 PolarHBondContact N-O 2.84Å; L121-F149 PolarHBondContact O-N 2.76Å; L123-F149 HydrophobicContact CD1-CD2 4.27Å; L123-F149 HydrophobicContact CD1-CE2 3.63Å; L123-F149 HydrophobicContact CD1-CZ 4.49Å; L123-F149 HydrophobicContact CG-CD2 4.38Å; L123-F149 HydrophobicContact CG-CE2 4.07Å; P147-F149 HydrophobicContact CB-CE2 4.31Å; F149-K164 HydrophobicContact CB-CB 4.43Å; F149-K164 HydrophobicContact CB-CD 3.77Å; F149-K164 HydrophobicContact CB-CG 3.86Å; F149-K164 HydrophobicContact CD1-CB 4.04Å; F149-K164 HydrophobicContact CD1-CD 3.72Å; F149-K164 HydrophobicContact CD1-CG 4.12Å; F149-K164 HydrophobicContact CD2-CB 3.78Å; F149-K164 HydrophobicContact CD2-CG 4.14Å; F149-K164 HydrophobicContact CE1-CB 4.21Å; F149-K164 HydrophobicContact CE1-CD 4.48Å; F149-K164 HydrophobicContact CE2-CB 4.01Å; F149-K164 HydrophobicContact CG-CB 3.8Å; F149-K164 HydrophobicContact CG-CD 3.77Å; F149-K164 HydrophobicContact CG-CG 3.76Å; F149-K164 HydrophobicContact CZ-CB 4.19Å; F149-K164 WeakPolarHBondContact CZ-O 3.3Å; F149-K167 HydrophobicContact CD1-CD 4.34Å; F149-K167 HydrophobicContact CE1-CB 4.04Å; F149-K167 HydrophobicContact CE1-CD 4.14Å; F149-L168 HydrophobicContact CE2-CD1 4.13Å; F149-L168 HydrophobicContact CZ-CD1 3.82Å; F149-L168 HydrophobicContact CZ-CD2 4.06Å; F149-L168 HydrophobicContact CZ-CG 3.77Å; F149-H225 AromaticContact CD1-NE2 3.77Å; F149-H225 AromaticContact CE1-CD2 3.95Å; F149-H225 AromaticContact CE1-NE2 3.24Å; F149-H225 WeakPolarHBondContact CE1-NE2 3.33Å
150W91.2Very high86.6Confident80 Ų8060.8 Ų60.830%0.30332%0.321SS..EExtended strand (participates in β ladder)trans-80.1136.4177.7-63.9-157.6000106.5R148 K164R148-W150 HydrophobicContact CB-CZ3 3.81Å; R148-W150 HydrophobicContact CG-CH2 4.05Å; R148-W150 HydrophobicContact CG-CZ3 3.65Å; W150-K164 PolarHBondContact O-NZ 3.49Å
151V92Very high87.6Confident12 Ų1259.7 Ų59.77%0.07332%0.315CS..  trans-129.9123.6-174.3-176.20000107.5K119 L121 K153 I156 I160K119-V151 VanDerWaalsContact CB-O 3.24Å; K119-V151 WeakPolarHBondContact CB-O 3.5Å; K119-V151 PolarHBondContact O-N 3.26Å; K119-V151 VanDerWaalsContact O-O 3.09Å; L121-V151 HydrophobicContact CB-CG2 3.99Å; V151-K153 HydrophobicContact CG1-CB 4.13Å; V151-I156 HydrophobicContact CB-CD1 4.41Å; V151-I156 HydrophobicContact CG1-CD1 4.46Å; V151-I156 HydrophobicContact CG1-CG1 4.45Å; V151-I156 HydrophobicContact CG2-CD1 4.24Å; V151-I160 HydrophobicContact CG1-CD1 4.37Å; V151-I160 HydrophobicContact CG1-CG2 4.22Å; V151-I160 HydrophobicContact CG2-CG2 4.35Å
152K85.8Confident88.9Confident221 Ų22155.2 Ų55.296%0.96128%0.284SS*.  trans-80.4-24.7176.9-66.2-173.6176.8-174.90112.8
153K79.7Confident89.9Confident111 Ų11156.7 Ų56.748%0.48328%0.281SS..SBendtrans-74.1141-178.5-75.3-177165.8-169.40110.5V151 I160V151-K153 HydrophobicContact CG1-CB 4.13Å; K153-I160 HydrophobicContact CB-CD1 3.97Å; K153-I160 HydrophobicContact CD-CD1 3.45Å; K153-I160 VanDerWaalsContact CD-CD1 3.45Å; K153-I160 HydrophobicContact CD-CG1 4.2Å; K153-I160 HydrophobicContact CG-CD1 4.3Å
154A75.7Confident90.7Very high85 Ų8554.7 Ų54.770%0.70227%0.274SS*.SBendtrans-66.2-39.3177.400000112.3
155T85.3Confident91.1Very high103 Ų10350.4 Ų50.463%0.63225%0.252SS*.SBendtrans-102137.3178.953.20000111I160T155-I160 VanDerWaalsContact O-CD1 3.25Å; T155-I160 WeakPolarHBondContact O-CD1 3.2Å
156I89.5Confident91.1Very high40 Ų4054 Ų5421%0.20527%0.268CS..  trans-104.693.4176.6-52.2-162.1000109.2L121 V151 I160 I161 P206L121-I156 HydrophobicContact CB-CD1 3.93Å; L121-I156 HydrophobicContact CD1-CG2 4.25Å; L121-I156 HydrophobicContact CD2-CG2 4.15Å; V151-I156 HydrophobicContact CB-CD1 4.41Å; V151-I156 HydrophobicContact CG1-CD1 4.46Å; V151-I156 HydrophobicContact CG1-CG1 4.45Å; V151-I156 HydrophobicContact CG2-CD1 4.24Å; I156-I160 HydrophobicContact CG2-CB 4.44Å; I156-I160 HydrophobicContact CG2-CG2 4.15Å; I156-I161 HydrophobicContact CG2-CD1 4.34Å; I156-I161 HydrophobicContact CG2-CG1 3.89Å; I156-P206 HydrophobicContact CB-CG 4.27Å; I156-P206 VanDerWaalsContact CD1-CD 3.47Å; I156-P206 HydrophobicContact CD1-CG 3.69Å; I156-P206 HydrophobicContact CG1-CG 4.31Å
157D92.1Very high90.9Very high61 Ų6155.6 Ų55.633%0.32628%0.275SS..  trans-87.2175178.763.838.7000112.7D159 I160 I161D157-D159 VanDerWaalsContact C-N 3.28Å; D157-D159 PolarHBondContact O-N 3.01Å; D157-D159 WeakPolarHBondContact OD1-CA 3.34Å; D157-D159 WeakPolarHBondContact OD1-CB 3.46Å; D157-D159 PolarHBondContact OD1-N 2.87Å; D157-I160 PolarHBondContact O-N 3.16Å; D157-I160 WeakPolarHBondContact OD1-CG1 3.26Å; D157-I160 PolarHBondContact OD1-N 2.9Å; D157-I161 WeakPolarHBondContact O-CG1 3.3Å; D157-I161 PolarHBondContact O-N 2.91Å; D157-I161 VanDerWaalsContact O-N 3.16Å
158A94.5Very high90.6Very high24 Ų2455.6 Ų55.620%0.19828%0.275CS..Hα-helixtrans-61.2-33.8179.200000113.1I161 K162 V181A158-I161 PolarHBondContact O-N 3.25Å; A158-K162 VanDerWaalsContact O-CG 3.22Å; A158-K162 WeakPolarHBondContact O-CG 3.15Å; A158-K162 PolarHBondContact O-N 2.84Å; A158-V181 HydrophobicContact CB-CG1 3.77Å
159D94Very high89.9Confident61 Ų6157 Ų5733%0.32628%0.283SS..Hα-helixtrans-67.9-42.5179.7171.858000111D157 I161 K162 R163D157-D159 VanDerWaalsContact C-N 3.28Å; D157-D159 PolarHBondContact O-N 3.01Å; D157-D159 WeakPolarHBondContact OD1-CA 3.34Å; D157-D159 WeakPolarHBondContact OD1-CB 3.46Å; D157-D159 PolarHBondContact OD1-N 2.87Å; D159-I161 VanDerWaalsContact C-N 3.33Å; D159-I161 PolarHBondContact O-N 3.11Å; D159-K162 PolarHBondContact O-N 3.39Å; D159-R163 VanDerWaalsContact O-CG 3.32Å; D159-R163 WeakPolarHBondContact O-CG 3.4Å; D159-R163 PolarHBondContact O-N 3.02Å; D159-R163 IonicContact OD1-CZ 3.57Å; D159-R163 IonicContact OD1-NE 3.02Å; D159-R163 PolarHBondContact OD1-NE 2.83Å; D159-R163 IonicContact OD1-NH2 2.76Å; D159-R163 PolarHBondContact OD1-NH2 3.04Å; D159-R163 IonicContact OD2-CZ 2.95Å; D159-R163 IonicContact OD2-NE 3.05Å; D159-R163 PolarHBondContact OD2-NE 2.92Å; D159-R163 IonicContact OD2-NH1 2.66Å; D159-R163 IonicContact OD2-NH2 3.34Å; D159-R163 PolarHBondContact OD2-NH2 2.74Å
160I94.2Very high89.1Confident13 Ų1361.6 Ų61.67%0.06731%0.305CS..Hα-helixtrans-59.7-46.8173.7-64.8169.9000110.2V151 K153 T155 I156 D157 K162 R163 K164V151-I160 HydrophobicContact CG1-CD1 4.37Å; V151-I160 HydrophobicContact CG1-CG2 4.22Å; V151-I160 HydrophobicContact CG2-CG2 4.35Å; K153-I160 HydrophobicContact CB-CD1 3.97Å; K153-I160 HydrophobicContact CD-CD1 3.45Å; K153-I160 VanDerWaalsContact CD-CD1 3.45Å; K153-I160 HydrophobicContact CD-CG1 4.2Å; K153-I160 HydrophobicContact CG-CD1 4.3Å; T155-I160 VanDerWaalsContact O-CD1 3.25Å; T155-I160 WeakPolarHBondContact O-CD1 3.2Å; I156-I160 HydrophobicContact CG2-CB 4.44Å; I156-I160 HydrophobicContact CG2-CG2 4.15Å; D157-I160 PolarHBondContact O-N 3.16Å; D157-I160 WeakPolarHBondContact OD1-CG1 3.26Å; D157-I160 PolarHBondContact OD1-N 2.9Å; I160-K162 PolarHBondContact O-N 2.98Å; I160-R163 PolarHBondContact O-N 2.86Å; I160-K164 HydrophobicContact CG2-CG 4.33Å; I160-K164 WeakPolarHBondContact O-CG 3.27Å; I160-K164 PolarHBondContact O-N 2.82Å
161I95.9Very high88.7Confident1 Ų165.3 Ų65.31%0.00532%0.32CS..Hα-helixtrans-60.3-47.9-180-62.3166.2000110.1L121 L123 I156 D157 A158 D159 R163 K164 V165 V181 I208 L210L121-I161 HydrophobicContact CD2-CG1 4.1Å; L123-I161 HydrophobicContact CD2-CG2 4.41Å; I156-I161 HydrophobicContact CG2-CD1 4.34Å; I156-I161 HydrophobicContact CG2-CG1 3.89Å; D157-I161 WeakPolarHBondContact O-CG1 3.3Å; D157-I161 PolarHBondContact O-N 2.91Å; D157-I161 VanDerWaalsContact O-N 3.16Å; A158-I161 PolarHBondContact O-N 3.25Å; D159-I161 VanDerWaalsContact C-N 3.33Å; D159-I161 PolarHBondContact O-N 3.11Å; I161-R163 PolarHBondContact O-N 3.02Å; I161-K164 PolarHBondContact O-N 2.73Å; I161-K164 VanDerWaalsContact O-N 3.12Å; I161-V165 HydrophobicContact CG2-CG2 4.16Å; I161-V165 VanDerWaalsContact O-CG2 3.27Å; I161-V165 WeakPolarHBondContact O-CG2 3.43Å; I161-V165 PolarHBondContact O-N 3.46Å; I161-V181 HydrophobicContact CB-CG1 4.15Å; I161-V181 HydrophobicContact CB-CG2 4.37Å; I161-V181 HydrophobicContact CG2-CG1 4.12Å; I161-V181 HydrophobicContact CG2-CG2 3.7Å; I161-I208 HydrophobicContact CD1-CG1 4.23Å; I161-I208 HydrophobicContact CD1-CG2 4.33Å; I161-L210 HydrophobicContact CG2-CD1 4.22Å; I161-L210 HydrophobicContact CG2-CD2 4.39Å
162K95.6Very high88.6Confident46 Ų4665.1 Ų65.120%0.232%0.319CS..Hα-helixtrans-54.6-49.9176.5-71.7172.1-171.5-167.40111.6A158 D159 I160 K164 V165 Q166 I177 N178 V181A158-K162 VanDerWaalsContact O-CG 3.22Å; A158-K162 WeakPolarHBondContact O-CG 3.15Å; A158-K162 PolarHBondContact O-N 2.84Å; D159-K162 PolarHBondContact O-N 3.39Å; I160-K162 PolarHBondContact O-N 2.98Å; K162-K164 VanDerWaalsContact C-N 3.29Å; K162-K164 PolarHBondContact O-N 2.97Å; K162-V165 PolarHBondContact O-N 3.42Å; K162-Q166 VanDerWaalsContact O-CG 3.31Å; K162-Q166 WeakPolarHBondContact O-CG 3.34Å; K162-Q166 PolarHBondContact O-N 2.78Å; K162-I177 HydrophobicContact CB-CG2 4.29Å; K162-I177 HydrophobicContact CG-CG2 4.16Å; K162-N178 WeakPolarHBondContact CD-OD1 3.27Å; K162-N178 WeakPolarHBondContact CE-OD1 3.36Å; K162-N178 PolarHBondContact NZ-OD1 3.15Å; K162-V181 HydrophobicContact CG-CB 4.05Å; K162-V181 HydrophobicContact CG-CG1 4.1Å; K162-V181 HydrophobicContact CG-CG2 3.75Å
163R92.8Very high88.7Confident138 Ų13858.4 Ų58.452%0.52129%0.293SS..Hα-helixtrans-62.2-34.3179.1-69.3177.2-165-171.66.3112.8D159 I160 I161 K167D159-R163 VanDerWaalsContact O-CG 3.32Å; D159-R163 WeakPolarHBondContact O-CG 3.4Å; D159-R163 PolarHBondContact O-N 3.02Å; D159-R163 IonicContact OD1-CZ 3.57Å; D159-R163 IonicContact OD1-NE 3.02Å; D159-R163 PolarHBondContact OD1-NE 2.83Å; D159-R163 IonicContact OD1-NH2 2.76Å; D159-R163 PolarHBondContact OD1-NH2 3.04Å; D159-R163 IonicContact OD2-CZ 2.95Å; D159-R163 IonicContact OD2-NE 3.05Å; D159-R163 PolarHBondContact OD2-NE 2.92Å; D159-R163 IonicContact OD2-NH1 2.66Å; D159-R163 IonicContact OD2-NH2 3.34Å; D159-R163 PolarHBondContact OD2-NH2 2.74Å; I160-R163 PolarHBondContact O-N 2.86Å; I161-R163 PolarHBondContact O-N 3.02Å; R163-K167 WeakPolarHBondContact O-CG 3.47Å
164K93.5Very high89.2Confident34 Ų3459.3 Ų59.315%0.14830%0.299CS..Hα-helixtrans-76.2-38.5176.6-63.4-43.8-171.9164.80112.1L121 F149 W150 I160 I161 K162 Q166 K167L121-K164 HydrophobicContact CD2-CB 4.2Å; L121-K164 HydrophobicContact CD2-CG 4.04Å; F149-K164 HydrophobicContact CB-CB 4.43Å; F149-K164 HydrophobicContact CB-CD 3.77Å; F149-K164 HydrophobicContact CB-CG 3.86Å; F149-K164 HydrophobicContact CD1-CB 4.04Å; F149-K164 HydrophobicContact CD1-CD 3.72Å; F149-K164 HydrophobicContact CD1-CG 4.12Å; F149-K164 HydrophobicContact CD2-CB 3.78Å; F149-K164 HydrophobicContact CD2-CG 4.14Å; F149-K164 HydrophobicContact CE1-CB 4.21Å; F149-K164 HydrophobicContact CE1-CD 4.48Å; F149-K164 HydrophobicContact CE2-CB 4.01Å; F149-K164 HydrophobicContact CG-CB 3.8Å; F149-K164 HydrophobicContact CG-CD 3.77Å; F149-K164 HydrophobicContact CG-CG 3.76Å; F149-K164 HydrophobicContact CZ-CB 4.19Å; F149-K164 WeakPolarHBondContact CZ-O 3.3Å; W150-K164 PolarHBondContact O-NZ 3.49Å; I160-K164 HydrophobicContact CG2-CG 4.33Å; I160-K164 WeakPolarHBondContact O-CG 3.27Å; I160-K164 PolarHBondContact O-N 2.82Å; I161-K164 PolarHBondContact O-N 2.73Å; I161-K164 VanDerWaalsContact O-N 3.12Å; K162-K164 VanDerWaalsContact C-N 3.29Å; K162-K164 PolarHBondContact O-N 2.97Å; K164-Q166 VanDerWaalsContact C-N 3.33Å; K164-Q166 PolarHBondContact O-N 3.05Å; K164-K167 HydrophobicContact CD-CD 4.24Å; K164-K167 WeakPolarHBondContact O-CB 3.32Å; K164-K167 PolarHBondContact O-N 2.77Å; K164-K167 VanDerWaalsContact O-N 3.09Å
165V93.8Very high90Very high0 Ų058.9 Ų58.90%029%0.291CS..Hα-helixtrans-61.2-43.1173.8172.60000111L123 I161 K162 K167 L168 N169 I177 L210 F219L123-V165 HydrophobicContact CD1-CG2 3.81Å; I161-V165 HydrophobicContact CG2-CG2 4.16Å; I161-V165 VanDerWaalsContact O-CG2 3.27Å; I161-V165 WeakPolarHBondContact O-CG2 3.43Å; I161-V165 PolarHBondContact O-N 3.46Å; K162-V165 PolarHBondContact O-N 3.42Å; V165-K167 PolarHBondContact O-N 3.1Å; V165-L168 PolarHBondContact O-N 2.98Å; V165-N169 PolarHBondContact O-N 2.95Å; V165-N169 VanDerWaalsContact O-N 3.15Å; V165-I177 HydrophobicContact CB-CG2 4.24Å; V165-I177 HydrophobicContact CG1-CD1 4.25Å; V165-I177 HydrophobicContact CG1-CG1 4.13Å; V165-I177 HydrophobicContact CG1-CG2 3.98Å; V165-L210 HydrophobicContact CG2-CD1 3.28Å; V165-F219 HydrophobicContact CG1-CE1 3.9Å; V165-F219 HydrophobicContact CG1-CZ 3.72Å
166Q91.7Very high90.2Very high81 Ų8156.8 Ų56.838%0.37927%0.274SS..THydrogen-bonded Turntrans-56.1-23.9175-76.6173.4-2400113.3K162 K164 L168 N169 I177K162-Q166 VanDerWaalsContact O-CG 3.31Å; K162-Q166 WeakPolarHBondContact O-CG 3.34Å; K162-Q166 PolarHBondContact O-N 2.78Å; K164-Q166 VanDerWaalsContact C-N 3.33Å; K164-Q166 PolarHBondContact O-N 3.05Å; Q166-L168 VanDerWaalsContact C-N 3.35Å; Q166-N169 WeakPolarHBondContact O-CB 3.41Å; Q166-N169 PolarHBondContact O-N 2.72Å; Q166-I177 HydrophobicContact CG-CD1 3.69Å
167K90.3Very high90.4Very high35 Ų3555 Ų5515%0.15227%0.265CS..THydrogen-bonded Turntrans-77.5-20.2178.2-64.6176.1-172.3-150.70114F149 R163 K164 V165 H225 S226 E227F149-K167 HydrophobicContact CD1-CD 4.34Å; F149-K167 HydrophobicContact CE1-CB 4.04Å; F149-K167 HydrophobicContact CE1-CD 4.14Å; R163-K167 WeakPolarHBondContact O-CG 3.47Å; K164-K167 HydrophobicContact CD-CD 4.24Å; K164-K167 WeakPolarHBondContact O-CB 3.32Å; K164-K167 PolarHBondContact O-N 2.77Å; K164-K167 VanDerWaalsContact O-N 3.09Å; V165-K167 PolarHBondContact O-N 3.1Å; K167-H225 WeakPolarHBondContact O-CA 3.47Å; K167-S226 VanDerWaalsContact CA-OG 3.25Å; K167-S226 WeakPolarHBondContact CA-OG 3.33Å; K167-S226 WeakPolarHBondContact CB-OG 3.14Å; K167-S226 PolarHBondContact O-N 2.94Å; K167-S226 PolarHBondContact O-OG 2.67Å; K167-E227 HydrophobicContact CD-CG 4.28Å; K167-E227 WeakPolarHBondContact CD-OE2 3.36Å; K167-E227 VanDerWaalsContact CE-OE1 3.3Å; K167-E227 WeakPolarHBondContact CE-OE1 3.32Å; K167-E227 WeakPolarHBondContact CE-OE2 3.29Å; K167-E227 IonicContact NZ-OE1 3.11Å; K167-E227 PolarHBondContact NZ-OE1 2.84Å; K167-E227 IonicContact NZ-OE2 3.79Å; K167-E227 PolarHBondContact NZ-OE2 2.98Å
168L88.1Confident90.5Very high0 Ų054.6 Ų54.60%026%0.263CS..THydrogen-bonded Turntrans-98.4-8.9173.7-58.4170.7000111.8L123 I125 P147 F149 V165 Q166 F219 Y233L123-L168 HydrophobicContact CD1-CD1 4.32Å; I125-L168 HydrophobicContact CD1-CD1 3.76Å; P147-L168 HydrophobicContact CB-CD1 3.5Å; P147-L168 HydrophobicContact CB-CD2 4.35Å; P147-L168 HydrophobicContact CG-CD1 3.96Å; F149-L168 HydrophobicContact CE2-CD1 4.13Å; F149-L168 HydrophobicContact CZ-CD1 3.82Å; F149-L168 HydrophobicContact CZ-CD2 4.06Å; F149-L168 HydrophobicContact CZ-CG 3.77Å; V165-L168 PolarHBondContact O-N 2.98Å; Q166-L168 VanDerWaalsContact C-N 3.35Å; L168-F219 HydrophobicContact CB-CD1 4.41Å; L168-F219 HydrophobicContact CB-CE1 4.34Å; L168-Y233 HydrophobicContact CD2-CD2 3.85Å; L168-Y233 HydrophobicContact CD2-CE1 4.46Å; L168-Y233 HydrophobicContact CD2-CE2 3.41Å; L168-Y233 VanDerWaalsContact CD2-CE2 3.41Å
169N79.3Confident90.5Very high44 Ų4457.3 Ų57.324%0.23528%0.277CS..  trans-71137.1-172.3-178.327.3000110.8V165 Q166 Y171 C172 I177V165-N169 PolarHBondContact O-N 2.95Å; V165-N169 VanDerWaalsContact O-N 3.15Å; Q166-N169 WeakPolarHBondContact O-CB 3.41Å; Q166-N169 PolarHBondContact O-N 2.72Å; N169-Y171 PolarHBondContact OD1-N 3.24Å; N169-Y171 VanDerWaalsContact OD1-N 3.14Å; N169-C172 PolarHBondContact ND2-O 2.97Å; N169-C172 VanDerWaalsContact OD1-CA 3.32Å; N169-C172 WeakPolarHBondContact OD1-CA 3.4Å; N169-C172 WeakPolarHBondContact OD1-CB 3.26Å; N169-C172 PolarHBondContact OD1-N 2.78Å; N169-C172 PolarHBondContact OD1-SG 3.07Å; N169-I177 HydrophobicContact CB-CD1 4.49Å
170H75.4Confident90.5Very high104 Ų10454.7 Ų54.748%0.48126%0.263SS..SBendtrans-107.1-46.9167.4-161.210.8000112.3
171Y84.2Confident90.6Very high158 Ų15854.1 Ų54.162%0.6226%0.26SS*.SBendtrans-132.9-8.4-173.9-55.6-72.3000115.6N169 N173 C218N169-Y171 PolarHBondContact OD1-N 3.24Å; N169-Y171 VanDerWaalsContact OD1-N 3.14Å; Y171-N173 PolarHBondContact O-N 3.44Å; Y171-C218 CarbonylContact C-O 3.55Å; Y171-C218 WeakPolarHBondContact CA-O 3.43Å; Y171-C218 WeakPolarHBondContact CB-O 3.33Å; Y171-C218 PolarHBondContact N-O 2.55Å
172C88.6Confident90.6Very high8 Ų860.3 Ų60.35%0.05429%0.289CS..  trans-57.6125.7178.9-49.80000110.8N169 E176 I177 C218N169-C172 PolarHBondContact ND2-O 2.97Å; N169-C172 VanDerWaalsContact OD1-CA 3.32Å; N169-C172 WeakPolarHBondContact OD1-CA 3.4Å; N169-C172 WeakPolarHBondContact OD1-CB 3.26Å; N169-C172 PolarHBondContact OD1-N 2.78Å; N169-C172 PolarHBondContact OD1-SG 3.07Å; C172-E176 WeakPolarHBondContact CA-OE2 3.44Å; C172-I177 HydrophobicContact CB-CD1 4.02Å; C172-I177 HydrophobicContact CB-CG1 3.75Å; C172-C218 HydrophobicContact CB-CB 3.71Å; C172-C218 WeakPolarHBondContact CB-SG 3.41Å; C172-C218 PolarHBondContact N-O 3.17Å; C172-C218 VanDerWaalsContact N-O 3.15Å; C172-C218 WeakPolarHBondContact SG-CB 3.37Å; C172-C218 PolarHBondContact SG-O 2.65Å; C172-C218 CovalentContact SG-SG 2.04Å; C172-C218 PolarHBondContact SG-SG 3.05Å
173N89Confident90.7Very high79 Ų7961.4 Ų61.442%0.42231%0.307SS..  trans-75.7165.1169.870.756.8000110.1Y171 S175 E176 I177Y171-N173 PolarHBondContact O-N 3.44Å; N173-S175 PolarHBondContact O-N 3.25Å; N173-S175 WeakPolarHBondContact OD1-CA 3.45Å; N173-S175 WeakPolarHBondContact OD1-CB 3.2Å; N173-S175 PolarHBondContact OD1-N 2.95Å; N173-E176 VanDerWaalsContact CG-OE2 3.26Å; N173-E176 PolarHBondContact N-OE2 3.39Å; N173-E176 PolarHBondContact ND2-OE2 3.22Å; N173-E176 PolarHBondContact O-N 3.38Å; N173-E176 PolarHBondContact OD1-N 2.76Å; N173-I177 PolarHBondContact O-N 3.36Å
174Q90.4Very high90.9Very high130 Ų13059.1 Ų59.161%0.60730%0.298SS*.Hα-helixtrans-65.1-28.8-176.4-165167.813.700113.1N178Q174-N178 WeakPolarHBondContact O-CB 3.48Å; Q174-N178 PolarHBondContact O-N 3.23Å; Q174-N178 PolarHBondContact O-ND2 3.08Å; Q174-N178 VanDerWaalsContact O-ND2 3.11Å
175S91.1Very high91.1Very high77 Ų7761.8 Ų61.854%0.53831%0.311SS..Hα-helixtrans-66.5-46.6176.2-168.60000111.4N173 I177 N178 V179N173-S175 PolarHBondContact O-N 3.25Å; N173-S175 WeakPolarHBondContact OD1-CA 3.45Å; N173-S175 WeakPolarHBondContact OD1-CB 3.2Å; N173-S175 PolarHBondContact OD1-N 2.95Å; S175-I177 PolarHBondContact O-N 2.92Å; S175-N178 WeakPolarHBondContact O-CB 3.49Å; S175-N178 PolarHBondContact O-N 3.4Å; S175-N178 VanDerWaalsContact O-N 3.12Å; S175-V179 WeakPolarHBondContact O-CG2 3.25Å; S175-V179 PolarHBondContact O-N 3.2Å
176E90.9Very high91.2Very high59 Ų5965.8 Ų65.828%0.27633%0.332SS..Hα-helixtrans-58.8-48176.7-69.9167.9140.600111.1C172 N173 N178 V179 M180C172-E176 WeakPolarHBondContact CA-OE2 3.44Å; N173-E176 VanDerWaalsContact CG-OE2 3.26Å; N173-E176 PolarHBondContact N-OE2 3.39Å; N173-E176 PolarHBondContact ND2-OE2 3.22Å; N173-E176 PolarHBondContact O-N 3.38Å; N173-E176 PolarHBondContact OD1-N 2.76Å; E176-N178 VanDerWaalsContact C-N 3.3Å; E176-N178 PolarHBondContact O-N 3.25Å; E176-V179 PolarHBondContact O-N 3.21Å; E176-M180 WeakPolarHBondContact O-CG 3.4Å; E176-M180 PolarHBondContact O-N 3.22Å
177I93Very high91.4Very high2 Ų263.3 Ų63.31%0.0132%0.32CS..Hα-helixtrans-60.9-41.3176.2-62.8176.5000111K162 V165 Q166 N169 C172 N173 S175 M180 V181K162-I177 HydrophobicContact CB-CG2 4.29Å; K162-I177 HydrophobicContact CG-CG2 4.16Å; V165-I177 HydrophobicContact CB-CG2 4.24Å; V165-I177 HydrophobicContact CG1-CD1 4.25Å; V165-I177 HydrophobicContact CG1-CG1 4.13Å; V165-I177 HydrophobicContact CG1-CG2 3.98Å; Q166-I177 HydrophobicContact CG-CD1 3.69Å; N169-I177 HydrophobicContact CB-CD1 4.49Å; C172-I177 HydrophobicContact CB-CD1 4.02Å; C172-I177 HydrophobicContact CB-CG1 3.75Å; N173-I177 PolarHBondContact O-N 3.36Å; S175-I177 PolarHBondContact O-N 2.92Å; I177-M180 HydrophobicContact CB-CE 4.47Å; I177-M180 HydrophobicContact CG1-CE 4.05Å; I177-M180 PolarHBondContact O-N 3.18Å; I177-V181 HydrophobicContact CG2-CG2 4.26Å; I177-V181 WeakPolarHBondContact O-CB 3.27Å; I177-V181 WeakPolarHBondContact O-CG2 3.37Å; I177-V181 PolarHBondContact O-N 3.28Å
178N94.6Very high91.7Very high53 Ų5362.3 Ų62.328%0.28332%0.315SS..Hα-helixtrans-60.8-47.1177.7-74.6-28.4000111.4K162 Q174 S175 E176 V181 Q182K162-N178 WeakPolarHBondContact CD-OD1 3.27Å; K162-N178 WeakPolarHBondContact CE-OD1 3.36Å; K162-N178 PolarHBondContact NZ-OD1 3.15Å; Q174-N178 WeakPolarHBondContact O-CB 3.48Å; Q174-N178 PolarHBondContact O-N 3.23Å; Q174-N178 PolarHBondContact O-ND2 3.08Å; Q174-N178 VanDerWaalsContact O-ND2 3.11Å; S175-N178 WeakPolarHBondContact O-CB 3.49Å; S175-N178 PolarHBondContact O-N 3.4Å; S175-N178 VanDerWaalsContact O-N 3.12Å; E176-N178 VanDerWaalsContact C-N 3.3Å; E176-N178 PolarHBondContact O-N 3.25Å; N178-V181 PolarHBondContact O-N 2.68Å; N178-Q182 VanDerWaalsContact O-CG 3.27Å; N178-Q182 WeakPolarHBondContact O-CG 3.49Å; N178-Q182 PolarHBondContact O-N 2.85Å
179V93.8Very high91.9Very high80 Ų8067.3 Ų67.349%0.48534%0.342SS..Hα-helixtrans-60.8-47.7177.5172.70000110.7S175 E176 V181 Q182 A183S175-V179 WeakPolarHBondContact O-CG2 3.25Å; S175-V179 PolarHBondContact O-N 3.2Å; E176-V179 PolarHBondContact O-N 3.21Å; V179-V181 VanDerWaalsContact C-N 3.34Å; V179-V181 PolarHBondContact O-N 2.7Å; V179-Q182 PolarHBondContact O-N 2.73Å; V179-A183 WeakPolarHBondContact O-CB 3.5Å; V179-A183 PolarHBondContact O-N 3.42Å
180M94.8Very high92.6Very high7 Ų765.8 Ų65.83%0.03434%0.337CS..Hα-helixtrans-57.3-45.7177.4-71.4-165.6-77.700112.4E176 I177 A183 R184 L210 H211 D212 F219E176-M180 WeakPolarHBondContact O-CG 3.4Å; E176-M180 PolarHBondContact O-N 3.22Å; I177-M180 HydrophobicContact CB-CE 4.47Å; I177-M180 HydrophobicContact CG1-CE 4.05Å; I177-M180 PolarHBondContact O-N 3.18Å; M180-A183 PolarHBondContact O-N 3.01Å; M180-R184 PolarHBondContact O-N 2.99Å; M180-R184 VanDerWaalsContact O-N 3.15Å; M180-L210 WeakPolarHBondContact O-CD2 3.32Å; M180-H211 VanDerWaalsContact CG-O 3.3Å; M180-H211 WeakPolarHBondContact CG-O 3.49Å; M180-D212 HydrophobicContact SD-CB 4.02Å; M180-F219 HydrophobicContact CE-CE2 3.71Å; M180-F219 HydrophobicContact CE-CZ 3.8Å; M180-F219 HydrophobicContact SD-CE2 3.82Å; M180-F219 HydrophobicContact SD-CZ 4.27Å
181V96.6Very high93.7Very high0 Ų060.9 Ų60.90%031%0.314CS..Hα-helixtrans-70.7-33.6-179.7175.50000111.6A158 I161 K162 I177 N178 V179 R184 L210A158-V181 HydrophobicContact CB-CG1 3.77Å; I161-V181 HydrophobicContact CB-CG1 4.15Å; I161-V181 HydrophobicContact CB-CG2 4.37Å; I161-V181 HydrophobicContact CG2-CG1 4.12Å; I161-V181 HydrophobicContact CG2-CG2 3.7Å; K162-V181 HydrophobicContact CG-CB 4.05Å; K162-V181 HydrophobicContact CG-CG1 4.1Å; K162-V181 HydrophobicContact CG-CG2 3.75Å; I177-V181 HydrophobicContact CG2-CG2 4.26Å; I177-V181 WeakPolarHBondContact O-CB 3.27Å; I177-V181 WeakPolarHBondContact O-CG2 3.37Å; I177-V181 PolarHBondContact O-N 3.28Å; N178-V181 PolarHBondContact O-N 2.68Å; V179-V181 VanDerWaalsContact C-N 3.34Å; V179-V181 PolarHBondContact O-N 2.7Å; V181-R184 VanDerWaalsContact O-CB 3.29Å; V181-R184 WeakPolarHBondContact O-CB 3.38Å; V181-R184 WeakPolarHBondContact O-CD 3.41Å; V181-R184 WeakPolarHBondContact O-CG 3.18Å; V181-R184 PolarHBondContact O-N 2.57Å; V181-R184 PolarHBondContact O-NH1 2.99Å; V181-L210 HydrophobicContact CG2-CD2 4.36Å
182Q96.1Very high94.2Very high131 Ų13153.3 Ų53.361%0.61229%0.285SS*.Hα-helixtrans-68.5-39.2175.2-70-62.20.600112.1N178 V179 R184N178-Q182 VanDerWaalsContact O-CG 3.27Å; N178-Q182 WeakPolarHBondContact O-CG 3.49Å; N178-Q182 PolarHBondContact O-N 2.85Å; V179-Q182 PolarHBondContact O-N 2.73Å; Q182-R184 PolarHBondContact O-N 3.07Å
183A96.3Very high94.5Very high70 Ų7056.1 Ų56.158%0.57930%0.296SS*.THydrogen-bonded Turntrans-81.84.3177.700000114.2V179 M180V179-A183 WeakPolarHBondContact O-CB 3.5Å; V179-A183 PolarHBondContact O-N 3.42Å; M180-A183 PolarHBondContact O-N 3.01Å
184R97.1Very high94.8Very high89 Ų8953.3 Ų53.334%0.33628%0.281SS..  trans-57.5151.8-175.376.2-172.4177.7-68.6-3.7112.6M180 V181 Q182 I208 H209 L210M180-R184 PolarHBondContact O-N 2.99Å; M180-R184 VanDerWaalsContact O-N 3.15Å; V181-R184 VanDerWaalsContact O-CB 3.29Å; V181-R184 WeakPolarHBondContact O-CB 3.38Å; V181-R184 WeakPolarHBondContact O-CD 3.41Å; V181-R184 WeakPolarHBondContact O-CG 3.18Å; V181-R184 PolarHBondContact O-N 2.57Å; V181-R184 PolarHBondContact O-NH1 2.99Å; Q182-R184 PolarHBondContact O-N 3.07Å; R184-I208 HydrophobicContact CB-CG2 3.85Å; R184-I208 HydrophobicContact CG-CG2 4.26Å; R184-H209 WeakPolarHBondContact CA-O 3.05Å; R184-L210 HydrophobicContact CB-CD2 3.54Å
185Q97.5Very high94.8Very high90 Ų9052.5 Ų52.542%0.42127%0.272SS..EExtended strand (participates in β ladder)trans-121.7136.1172.8-62.1-176.1-22.100110.4Y187 H209Q185-Y187 HydrophobicContact CB-CD1 4Å; Q185-Y187 HydrophobicContact CB-CE1 3.53Å; Q185-Y187 HydrophobicContact CG-CE1 4.41Å; Q185-Y187 PolarHBondContact OE1-OH 3.21Å; Q185-H209 HydrophobicContact CB-CB 4.36Å; Q185-H209 PolarHBondContact N-O 3.4Å; Q185-H209 PolarHBondContact O-N 3.23Å
186N95.9Very high94.9Very high84 Ų8450.8 Ų50.845%0.44926%0.256SS..EExtended strand (participates in β ladder)trans-85.4117170-172.1-3000109H188 I208N186-H188 PolarHBondContact OD1-N 3.31Å; N186-H188 PolarHBondContact OD1-O 2.95Å; N186-I208 HydrophobicContact CB-CD1 4.06Å
187Y96.8Very high95.2Very high29 Ų2948 Ų4811%0.11424%0.243CC..EExtended strand (participates in β ladder)trans-99.7-18.3-179.4-74.7-8000113.9L124 Q185 I207 H209 P244 R245 A248L124-Y187 HydrophobicContact CD2-CD2 4.21Å; L124-Y187 HydrophobicContact CD2-CE2 4.16Å; Q185-Y187 HydrophobicContact CB-CD1 4Å; Q185-Y187 HydrophobicContact CB-CE1 3.53Å; Q185-Y187 HydrophobicContact CG-CE1 4.41Å; Q185-Y187 PolarHBondContact OE1-OH 3.21Å; Y187-I207 PolarHBondContact N-O 2.62Å; Y187-H209 HydrophobicContact CD1-CB 4.35Å; Y187-H209 HydrophobicContact CD2-CB 3.55Å; Y187-H209 HydrophobicContact CE1-CB 4.1Å; Y187-H209 HydrophobicContact CE2-CB 3.25Å; Y187-H209 AromaticContact CE2-CG 3.42Å; Y187-H209 VanDerWaalsContact CE2-CG 3.42Å; Y187-H209 AromaticContact CE2-ND1 3.88Å; Y187-H209 HydrophobicContact CG-CB 4.11Å; Y187-H209 AromaticContact CZ-CG 3.58Å; Y187-H209 AromaticContact CZ-ND1 3.54Å; Y187-H209 PolarHBondContact OH-ND1 3.39Å; Y187-H209 VanDerWaalsContact OH-ND1 3.07Å; Y187-P244 HydrophobicContact CE2-CB 3.86Å; Y187-R245 HydrophobicContact CD1-CB 4.26Å; Y187-R245 HydrophobicContact CD1-CG 4.13Å; Y187-R245 HydrophobicContact CD2-CB 4.11Å; Y187-R245 HydrophobicContact CD2-CG 4.5Å; Y187-R245 HydrophobicContact CE1-CB 4.13Å; Y187-R245 HydrophobicContact CE1-CG 4.41Å; Y187-R245 HydrophobicContact CE2-CB 3.96Å; Y187-R245 HydrophobicContact CG-CB 4.25Å; Y187-R245 HydrophobicContact CG-CG 4.18Å; Y187-A248 HydrophobicContact CD2-CB 3.76Å; Y187-A248 HydrophobicContact CG-CB 4.36Å
188H95.7Very high95.4Very high14 Ų1448 Ų487%0.06524%0.243CC..EExtended strand (participates in β ladder)trans-163.8144.6-179.8177.672.6000109.2N186 Y191 P206 I207 I253N186-H188 PolarHBondContact OD1-N 3.31Å; N186-H188 PolarHBondContact OD1-O 2.95Å; H188-Y191 PolarHBondContact NE2-O 2.85Å; H188-P206 CarbonylContact O-C 3.39Å; H188-P206 WeakPolarHBondContact O-CA 3.14Å; H188-I207 HydrophobicContact CB-CB 3.99Å; H188-I207 HydrophobicContact CB-CD1 3.76Å; H188-I207 HydrophobicContact CB-CG1 3.91Å; H188-I207 PolarHBondContact O-N 2.93Å; H188-I253 PolarHBondContact CE1-O 2.54Å
189D93.3Very high95.5Very high105 Ų10546.4 Ų46.456%0.56123%0.234SC*.EExtended strand (participates in β ladder)trans-139132.2166.1-164.15.8000109.1G205D189-G205 VanDerWaalsContact OD1-C 3.31Å
190G94.5Very high95.7Very high13 Ų1343.2 Ų43.213%0.13422%0.215CC..EExtended strand (participates in β ladder)trans130.6-143.4-174.900000112.5L192 E204 G205G190-L192 PolarHBondContact O-N 3.14Å; G190-E204 VanDerWaalsContact C-CG 3.44Å; G190-E204 CarbonylContact O-C 3.5Å; G190-E204 VanDerWaalsContact O-CA 3.27Å; G190-E204 WeakPolarHBondContact O-CA 3.26Å; G190-E204 VanDerWaalsContact O-CG 3.32Å; G190-E204 WeakPolarHBondContact O-CG 3.2Å; G190-G205 PolarHBondContact N-O 2.91Å; G190-G205 PolarHBondContact O-N 3.4Å; G190-G205 VanDerWaalsContact O-O 3.12Å
191Y96.7Very high95.9Very high0 Ų042.9 Ų42.90%021%0.213CC..EExtended strand (participates in β ladder)trans-63.3131.3-172.9-175.5-88000112.2N99 Y101 E102 H188 K193 N197 W202 G252 I253N99-Y191 PolarHBondContact ND2-OH 2.82Å; Y101-Y191 VanDerWaalsContact CD1-CB 3.49Å; Y101-Y191 HydrophobicContact CD1-CD2 4.03Å; Y101-Y191 AromaticContact CD1-CG 3.85Å; Y101-Y191 HydrophobicContact CD1-CG 3.85Å; Y101-Y191 AromaticContact CD2-CD2 3.17Å; Y101-Y191 HydrophobicContact CD2-CD2 3.17Å; Y101-Y191 AromaticContact CD2-CE2 3.81Å; Y101-Y191 HydrophobicContact CD2-CE2 3.81Å; Y101-Y191 AromaticContact CD2-CG 3.87Å; Y101-Y191 HydrophobicContact CD2-CG 3.87Å; Y101-Y191 HydrophobicContact CE1-CD2 4.49Å; Y101-Y191 HydrophobicContact CE1-CG 4.3Å; Y101-Y191 AromaticContact CE2-CD2 3.76Å; Y101-Y191 HydrophobicContact CE2-CD2 3.76Å; Y101-Y191 HydrophobicContact CE2-CG 4.35Å; Y101-Y191 HydrophobicContact CG-CD1 4.43Å; Y101-Y191 AromaticContact CG-CD2 3.33Å; Y101-Y191 HydrophobicContact CG-CD2 3.33Å; Y101-Y191 AromaticContact CG-CE2 3.96Å; Y101-Y191 HydrophobicContact CG-CE2 3.96Å; Y101-Y191 AromaticContact CG-CG 3.59Å; Y101-Y191 HydrophobicContact CG-CG 3.59Å; E102-Y191 VanDerWaalsContact CD-OH 3.31Å; E102-Y191 HydrophobicContact CG-CE1 4.27Å; E102-Y191 VanDerWaalsContact CG-OH 3.27Å; E102-Y191 WeakPolarHBondContact CG-OH 3.25Å; E102-Y191 WeakPolarHBondContact OE1-CE1 3.27Å; E102-Y191 VanDerWaalsContact OE1-CZ 3.24Å; E102-Y191 PolarHBondContact OE1-OH 2.81Å; H188-Y191 PolarHBondContact NE2-O 2.85Å; Y191-K193 HydrophobicContact CE1-CG 4.23Å; Y191-N197 VanDerWaalsContact CZ-ND2 3.27Å; Y191-N197 PolarHBondContact OH-ND2 3.45Å; Y191-W202 HydrophobicContact CD2-CB 4.08Å; Y191-W202 AromaticContact CD2-CD1 3.32Å; Y191-W202 AromaticContact CD2-CG 3.75Å; Y191-W202 HydrophobicContact CD2-CG 3.75Å; Y191-W202 AromaticContact CD2-NE1 3.94Å; Y191-W202 HydrophobicContact CE2-CB 3.4Å; Y191-W202 AromaticContact CE2-CD1 3.57Å; Y191-W202 HydrophobicContact CE2-CD2 4.34Å; Y191-W202 AromaticContact CE2-CG 3.47Å; Y191-W202 HydrophobicContact CE2-CG 3.47Å; Y191-W202 VanDerWaalsContact CE2-CG 3.47Å; Y191-G252 CarbonylContact O-C 3.57Å; Y191-G252 VanDerWaalsContact O-CA 3.26Å; Y191-G252 WeakPolarHBondContact O-CA 3.47Å; Y191-I253 WeakPolarHBondContact CB-O 3.11Å; Y191-I253 HydrophobicContact CD1-CB 3.81Å; Y191-I253 HydrophobicContact CD1-CD1 3.65Å; Y191-I253 HydrophobicContact CD1-CG1 3.73Å; Y191-I253 HydrophobicContact CE1-CD1 3.63Å; Y191-I253 HydrophobicContact CE1-CG1 4.17Å; Y191-I253 HydrophobicContact CG-CB 4.31Å; Y191-I253 PolarHBondContact O-N 2.78Å
192L96.7Very high95.9Very high0 Ų043.4 Ų43.40%022%0.215CC..EExtended strand (participates in β ladder)trans-112.6122179-63.9174000109.7A120 Y122 G190 N194 N197 L203 G205 I207A120-L192 HydrophobicContact CB-CD1 4.05Å; Y122-L192 HydrophobicContact CD1-CD1 3.92Å; Y122-L192 HydrophobicContact CD2-CB 4.44Å; Y122-L192 HydrophobicContact CD2-CD1 4.49Å; Y122-L192 HydrophobicContact CD2-CD2 3.94Å; Y122-L192 HydrophobicContact CE1-CB 4.41Å; Y122-L192 HydrophobicContact CE1-CD1 4.09Å; Y122-L192 HydrophobicContact CE2-CB 4Å; Y122-L192 HydrophobicContact CE2-CD2 4.32Å; Y122-L192 HydrophobicContact CG-CD1 4.14Å; Y122-L192 HydrophobicContact CG-CD2 4.18Å; G190-L192 PolarHBondContact O-N 3.14Å; L192-N194 PolarHBondContact O-N 3.42Å; L192-N197 PolarHBondContact O-ND2 3.17Å; L192-L203 HydrophobicContact CB-CB 3.95Å; L192-L203 PolarHBondContact N-O 2.91Å; L192-G205 WeakPolarHBondContact CD2-O 3.31Å; L192-I207 HydrophobicContact CD2-CD1 4.02Å; L192-I207 HydrophobicContact CD2-CG1 3.54Å
193K94.4Very high95.9Very high67 Ų6737.2 Ų37.229%0.29119%0.186SC..  trans-65.5129.5177.4-64.9-174.8-168.2158.70110Y122 Y191 I250 F251 G252 I253Y122-K193 PolarHBondContact OH-O 3.04Å; Y191-K193 HydrophobicContact CE1-CG 4.23Å; K193-I250 WeakPolarHBondContact CD-O 3.5Å; K193-I250 WeakPolarHBondContact CE-O 3.43Å; K193-I250 PolarHBondContact NZ-O 2.86Å; K193-F251 PolarHBondContact N-O 2.86Å; K193-G252 WeakPolarHBondContact CE-O 3.48Å; K193-I253 HydrophobicContact CD-CG1 4.47Å; K193-I253 VanDerWaalsContact CE-CG1 3.47Å; K193-I253 HydrophobicContact CG-CD1 4.37Å; K193-I253 HydrophobicContact CG-CG1 4.18Å
194N93.9Very high95.9Very high19 Ų1935.5 Ų35.510%0.10217%0.166CC..  trans-153.4144.4176.3-162.4-62.1000110.2Y122 R148 L192 Q196 N197 L203Y122-N194 WeakPolarHBondContact OH-CB 3.43Å; Y122-N194 PolarHBondContact OH-ND2 3.29Å; R148-N194 PolarHBondContact NH1-ND2 2.74Å; R148-N194 PolarHBondContact NH1-OD1 2.76Å; L192-N194 PolarHBondContact O-N 3.42Å; N194-Q196 PolarHBondContact O-N 2.98Å; N194-Q196 WeakPolarHBondContact OD1-CB 3.4Å; N194-Q196 PolarHBondContact OD1-N 2.82Å; N194-N197 PolarHBondContact N-ND2 2.68Å; N194-N197 WeakPolarHBondContact O-CB 3.33Å; N194-N197 PolarHBondContact O-N 3.21Å; N194-N197 VanDerWaalsContact O-N 3.07Å; N194-L203 HydrophobicContact CB-CD1 3.76Å; N194-L203 HydrophobicContact CB-CG 4.17Å; N194-L203 WeakPolarHBondContact ND2-CD1 3.36Å
195R91Very high95.8Very high114 Ų11431.4 Ų31.443%0.4315%0.151SC..THydrogen-bonded Turntrans-64.7-20.3175.5-67.7-172.6173-165.4-3.6113.4P50 Y143 N197P50-R195 HydrophobicContact CG-CB 3.77Å; Y143-R195 VanDerWaalsContact CD1-NH2 3.3Å; R195-N197 VanDerWaalsContact C-N 3.34Å
196Q93.7Very high95.7Very high41 Ų4127.6 Ų27.619%0.19213%0.134CC..THydrogen-bonded Turntrans-83.2-11.1175.7-65.4-177.2-37.900113.2Y49 P50 L112 N194Y49-Q196 PolarHBondContact OH-O 2.92Å; P50-Q196 HydrophobicContact CB-CG 4.46Å; P50-Q196 HydrophobicContact CG-CG 4.49Å; L112-Q196 HydrophobicContact CD2-CB 4.25Å; N194-Q196 PolarHBondContact O-N 2.98Å; N194-Q196 WeakPolarHBondContact OD1-CB 3.4Å; N194-Q196 PolarHBondContact OD1-N 2.82Å
197N96.6Very high95.8Very high1 Ų123.6 Ų23.61%0.00511%0.113CC..  trans-62.4145.8173.1-66-5.6000109.3T104 Y191 L192 N194 R195 A201 W202 L203T104-N197 HydrophobicContact CG2-CB 4.23Å; Y191-N197 VanDerWaalsContact CZ-ND2 3.27Å; Y191-N197 PolarHBondContact OH-ND2 3.45Å; L192-N197 PolarHBondContact O-ND2 3.17Å; N194-N197 PolarHBondContact N-ND2 2.68Å; N194-N197 WeakPolarHBondContact O-CB 3.33Å; N194-N197 PolarHBondContact O-N 3.21Å; N194-N197 VanDerWaalsContact O-N 3.07Å; R195-N197 VanDerWaalsContact C-N 3.34Å; N197-A201 WeakPolarHBondContact CA-O 3.44Å; N197-W202 HydrophobicContact CB-CB 4.14Å; N197-W202 WeakPolarHBondContact OD1-CA 3.27Å; N197-L203 PolarHBondContact OD1-N 2.95Å
198T97.6Very high95.9Very high0 Ų022.7 Ų22.70%011%0.11CC..  trans-126.3177.1177.570.50000109.3Y49 N99 T104 F106 G108 N200 A201Y49-T198 HydrophobicContact CE2-CG2 3.84Å; N99-T198 PolarHBondContact ND2-O 3.48Å; T104-T198 VanDerWaalsContact CG2-C 3.49Å; T104-T198 WeakPolarHBondContact CG2-O 3.14Å; T104-T198 WeakPolarHBondContact OG1-CA 3.33Å; F106-T198 HydrophobicContact CD1-CG2 3.95Å; F106-T198 CarbonylContact O-C 3.45Å; F106-T198 WeakPolarHBondContact O-CA 3.29Å; F106-T198 WeakPolarHBondContact O-CB 3.2Å; G108-T198 VanDerWaalsContact O-CB 3.25Å; G108-T198 WeakPolarHBondContact O-CB 3.15Å; G108-T198 PolarHBondContact O-OG1 3Å; T198-N200 PolarHBondContact O-N 3.16Å; T198-N200 VanDerWaalsContact O-N 3.17Å; T198-N200 PolarHBondContact OG1-N 3.03Å; T198-N200 VanDerWaalsContact OG1-N 3.14Å; T198-A201 PolarHBondContact N-O 2.69Å; T198-A201 PolarHBondContact OG1-N 2.98Å; T198-A201 PolarHBondContact OG1-O 2.69Å
199D97.4Very high96Very high21 Ų2122.9 Ų22.911%0.11211%0.111CC..SBendtrans-69-7173.7-64.9-11.8000112.3Y73 R98 N99 T104 F106Y73-D199 WeakPolarHBondContact CE1-OD2 3.5Å; Y73-D199 VanDerWaalsContact CZ-OD2 3.29Å; Y73-D199 VanDerWaalsContact OH-CG 3.31Å; Y73-D199 PolarHBondContact OH-OD1 2.81Å; Y73-D199 PolarHBondContact OH-OD2 3.16Å; R98-D199 CarbonylContact C-O 3.6Å; R98-D199 WeakPolarHBondContact CA-O 3.48Å; N99-D199 WeakPolarHBondContact CB-O 3.37Å; N99-D199 PolarHBondContact N-O 2.9Å; T104-D199 PolarHBondContact N-OD1 3.17Å; T104-D199 PolarHBondContact OG1-N 3.31Å; T104-D199 PolarHBondContact OG1-OD1 2.84Å; F106-D199 PolarHBondContact O-N 3.25Å
200N97.7Very high96.2Very high13 Ų1317.9 Ų17.97%0.078%0.084CC..SBendtrans-134.2-5.7-175.9-50.5102.5000115W96 I97 S107 G108 Y115 G116 T198W96-N200 HydrophobicContact CB-CB 4.31Å; W96-N200 WeakPolarHBondContact CB-ND2 3.46Å; W96-N200 HydrophobicContact CE3-CB 4.49Å; I97-N200 WeakPolarHBondContact O-CA 3.43Å; I97-N200 WeakPolarHBondContact O-CB 3.34Å; I97-N200 PolarHBondContact O-ND2 3.01Å; S107-N200 WeakPolarHBondContact CA-OD1 3.34Å; S107-N200 WeakPolarHBondContact CB-OD1 3.47Å; G108-N200 PolarHBondContact N-OD1 2.97Å; Y115-N200 CarbonylContact C-O 3.58Å; Y115-N200 HydrophobicContact CD1-CB 3.85Å; Y115-N200 HydrophobicContact CE1-CB 4.19Å; G116-N200 PolarHBondContact N-O 3.18Å; T198-N200 PolarHBondContact O-N 3.16Å; T198-N200 VanDerWaalsContact O-N 3.17Å; T198-N200 PolarHBondContact OG1-N 3.03Å; T198-N200 VanDerWaalsContact OG1-N 3.14Å
201A97.8Very high96.2Very high0 Ų020.2 Ų20.20%09%0.091CC..EExtended strand (participates in β ladder)trans-149.3132.3176.800000109.6K109 L112 E114 G116 N197 T198K109-A201 HydrophobicContact CG-CB 4.3Å; L112-A201 HydrophobicContact CB-CB 4.08Å; L112-A201 VanDerWaalsContact CD1-C 3.47Å; L112-A201 HydrophobicContact CD1-CB 3.81Å; L112-A201 WeakPolarHBondContact CD1-O 3.38Å; L112-A201 HydrophobicContact CG-CB 4.49Å; E114-A201 VanDerWaalsContact O-CB 3.27Å; E114-A201 WeakPolarHBondContact O-CB 3.45Å; G116-A201 WeakPolarHBondContact O-CA 3.38Å; N197-A201 WeakPolarHBondContact CA-O 3.44Å; T198-A201 PolarHBondContact N-O 2.69Å; T198-A201 PolarHBondContact OG1-N 2.98Å; T198-A201 PolarHBondContact OG1-O 2.69Å
202W97.5Very high96.1Very high11 Ų1120.4 Ų20.44%0.0429%0.092CC..EExtended strand (participates in β ladder)trans-145.9163-177.459.791.3000112I97 R98 N99 Y101 G116 P117 N118 Y191 N197I97-W202 HydrophobicContact CG2-CH2 3.87Å; I97-W202 HydrophobicContact CG2-CZ3 4.18Å; R98-W202 WeakPolarHBondContact O-CH2 3.28Å; N99-W202 HydrophobicContact CB-CD2 4.4Å; N99-W202 HydrophobicContact CB-CE3 3.62Å; N99-W202 HydrophobicContact CB-CZ3 3.82Å; Y101-W202 HydrophobicContact CE2-CZ2 4.28Å; Y101-W202 AromaticContact CE2-NE1 3.7Å; G116-W202 PolarHBondContact O-N 3.4Å; P117-W202 CarbonylContact C-O 3.59Å; P117-W202 HydrophobicContact CG-CZ2 3.67Å; N118-W202 PolarHBondContact N-O 3.45Å; Y191-W202 HydrophobicContact CD2-CB 4.08Å; Y191-W202 AromaticContact CD2-CD1 3.32Å; Y191-W202 AromaticContact CD2-CG 3.75Å; Y191-W202 HydrophobicContact CD2-CG 3.75Å; Y191-W202 AromaticContact CD2-NE1 3.94Å; Y191-W202 HydrophobicContact CE2-CB 3.4Å; Y191-W202 AromaticContact CE2-CD1 3.57Å; Y191-W202 HydrophobicContact CE2-CD2 4.34Å; Y191-W202 AromaticContact CE2-CG 3.47Å; Y191-W202 HydrophobicContact CE2-CG 3.47Å; Y191-W202 VanDerWaalsContact CE2-CG 3.47Å; N197-W202 HydrophobicContact CB-CB 4.14Å; N197-W202 WeakPolarHBondContact OD1-CA 3.27Å
203L96.4Very high95.6Very high1 Ų125.4 Ų25.41%0.00512%0.119CC..EExtended strand (participates in β ladder)trans-81.9139.1172.1-61.2-169.3000111.7L112 N118 A120 Y122 L192 N194 N197L112-L203 HydrophobicContact CD1-CD2 4.44Å; L112-L203 HydrophobicContact CD2-CD2 3.71Å; N118-L203 HydrophobicContact CB-CD2 4.02Å; N118-L203 WeakPolarHBondContact O-CA 3.42Å; A120-L203 HydrophobicContact CB-CB 4.31Å; A120-L203 HydrophobicContact CB-CD1 4.06Å; A120-L203 HydrophobicContact CB-CD2 4.25Å; A120-L203 HydrophobicContact CB-CG 4.45Å; Y122-L203 HydrophobicContact CE1-CD1 4.15Å; L192-L203 HydrophobicContact CB-CB 3.95Å; L192-L203 PolarHBondContact N-O 2.91Å; N194-L203 HydrophobicContact CB-CD1 3.76Å; N194-L203 HydrophobicContact CB-CG 4.17Å; N194-L203 WeakPolarHBondContact ND2-CD1 3.36Å; N197-L203 PolarHBondContact OD1-N 2.95Å
204E95.3Very high95.1Very high34 Ų3423.4 Ų23.416%0.15911%0.114CC..EExtended strand (participates in β ladder)trans-138.9141.3175.4-162-173.3103.500110.7P117 N118 K119 A120 G190P117-E204 HydrophobicContact CB-CB 3.96Å; P117-E204 WeakPolarHBondContact CB-OE2 3.49Å; P117-E204 WeakPolarHBondContact CG-OE2 3.36Å; N118-E204 PolarHBondContact O-N 3.41Å; K119-E204 VanDerWaalsContact CA-O 3.28Å; K119-E204 WeakPolarHBondContact CA-O 3.27Å; K119-E204 IonicContact NZ-OE1 3.96Å; K119-E204 PolarHBondContact NZ-OE1 3.39Å; A120-E204 PolarHBondContact N-O 3.06Å; G190-E204 VanDerWaalsContact C-CG 3.44Å; G190-E204 CarbonylContact O-C 3.5Å; G190-E204 VanDerWaalsContact O-CA 3.27Å; G190-E204 WeakPolarHBondContact O-CA 3.26Å; G190-E204 VanDerWaalsContact O-CG 3.32Å; G190-E204 WeakPolarHBondContact O-CG 3.2Å
205G95.1Very high94.1Very high2 Ų230.6 Ų30.62%0.02115%0.152CC..EExtended strand (participates in β ladder)trans149.4-165.7175.300000112.2A120 D189 G190 L192A120-G205 WeakPolarHBondContact O-CA 3.45Å; D189-G205 VanDerWaalsContact OD1-C 3.31Å; G190-G205 PolarHBondContact N-O 2.91Å; G190-G205 PolarHBondContact O-N 3.4Å; G190-G205 VanDerWaalsContact O-O 3.12Å; L192-G205 WeakPolarHBondContact CD2-O 3.31Å
206P95.8Very high93.3Very high11 Ų1137 Ų377%0.07118%0.176CC..EExtended strand (participates in β ladder)trans-87152-170.733-36.1000113.9L121 Y122 I156 H188 I208L121-P206 HydrophobicContact CD1-CG 4Å; Y122-P206 PolarHBondContact N-O 3.15Å; I156-P206 HydrophobicContact CB-CG 4.27Å; I156-P206 VanDerWaalsContact CD1-CD 3.47Å; I156-P206 HydrophobicContact CD1-CG 3.69Å; I156-P206 HydrophobicContact CG1-CG 4.31Å; H188-P206 CarbonylContact O-C 3.39Å; H188-P206 WeakPolarHBondContact O-CA 3.14Å; P206-I208 HydrophobicContact CB-CD1 3.81Å; P206-I208 HydrophobicContact CB-CG1 4.08Å; P206-I208 HydrophobicContact CG-CD1 4.31Å; P206-I208 HydrophobicContact CG-CG1 4.22Å
207I98Very high92.7Very high0 Ų035.9 Ų35.90%018%0.176CC..EExtended strand (participates in β ladder)trans-102.2105.9159.2-53.3173.1000107.6Y122 L146 Y187 H188 L192 A248 F251Y122-I207 HydrophobicContact CD2-CG1 4.44Å; Y122-I207 WeakPolarHBondContact O-CA 3.44Å; L146-I207 HydrophobicContact CD1-CG2 4.01Å; Y187-I207 PolarHBondContact N-O 2.62Å; H188-I207 HydrophobicContact CB-CB 3.99Å; H188-I207 HydrophobicContact CB-CD1 3.76Å; H188-I207 HydrophobicContact CB-CG1 3.91Å; H188-I207 PolarHBondContact O-N 2.93Å; L192-I207 HydrophobicContact CD2-CD1 4.02Å; L192-I207 HydrophobicContact CD2-CG1 3.54Å; I207-A248 VanDerWaalsContact CD1-O 3.24Å; I207-A248 WeakPolarHBondContact CD1-O 3.25Å; I207-A248 HydrophobicContact CG2-CB 3.9Å; I207-F251 HydrophobicContact CD1-CB 3.93Å
208I97.8Very high92.3Very high10 Ų1036.3 Ų36.35%0.05118%0.179CC..EExtended strand (participates in β ladder)trans-97.4124-179.6-58.6-58.7000109.5L121 Y122 L123 L124 I161 R184 N186 P206 L210L121-I208 HydrophobicContact CD1-CB 4.15Å; L121-I208 HydrophobicContact CD1-CG1 3.61Å; Y122-I208 PolarHBondContact O-N 3.14Å; L123-I208 WeakPolarHBondContact CA-O 3.3Å; L123-I208 HydrophobicContact CD2-CB 4.13Å; L124-I208 PolarHBondContact N-O 3.16Å; I161-I208 HydrophobicContact CD1-CG1 4.23Å; I161-I208 HydrophobicContact CD1-CG2 4.33Å; R184-I208 HydrophobicContact CB-CG2 3.85Å; R184-I208 HydrophobicContact CG-CG2 4.26Å; N186-I208 HydrophobicContact CB-CD1 4.06Å; P206-I208 HydrophobicContact CB-CD1 3.81Å; P206-I208 HydrophobicContact CB-CG1 4.08Å; P206-I208 HydrophobicContact CG-CD1 4.31Å; P206-I208 HydrophobicContact CG-CG1 4.22Å; I208-L210 HydrophobicContact CG2-CD2 4.06Å; I208-L210 HydrophobicContact CG2-CG 4.29Å
209H98.2Very high91.9Very high17 Ų1736.3 Ų36.38%0.07918%0.179CC..EExtended strand (participates in β ladder)trans-87.1131.5170.3173.6-115.1000111.1L124 T126 R184 Q185 Y187L124-H209 CarbonylContact O-C 3.38Å; L124-H209 VanDerWaalsContact O-CA 3.3Å; L124-H209 WeakPolarHBondContact O-CA 3.32Å; L124-H209 PolarHBondContact O-CD2 2.68Å; L124-H209 VanDerWaalsContact O-CD2 3.31Å; T126-H209 PolarHBondContact OG1-NE2 3.25Å; R184-H209 WeakPolarHBondContact CA-O 3.05Å; Q185-H209 HydrophobicContact CB-CB 4.36Å; Q185-H209 PolarHBondContact N-O 3.4Å; Q185-H209 PolarHBondContact O-N 3.23Å; Y187-H209 HydrophobicContact CD1-CB 4.35Å; Y187-H209 HydrophobicContact CD2-CB 3.55Å; Y187-H209 HydrophobicContact CE1-CB 4.1Å; Y187-H209 HydrophobicContact CE2-CB 3.25Å; Y187-H209 AromaticContact CE2-CG 3.42Å; Y187-H209 VanDerWaalsContact CE2-CG 3.42Å; Y187-H209 AromaticContact CE2-ND1 3.88Å; Y187-H209 HydrophobicContact CG-CB 4.11Å; Y187-H209 AromaticContact CZ-CG 3.58Å; Y187-H209 AromaticContact CZ-ND1 3.54Å; Y187-H209 PolarHBondContact OH-ND1 3.39Å; Y187-H209 VanDerWaalsContact OH-ND1 3.07Å
210L97.4Very high91.4Very high1 Ų135.7 Ų35.71%0.00518%0.178CC..EExtended strand (participates in β ladder)trans-126.7136.9174.5-58.7174000107.8L123 L124 I125 T126 I161 V165 M180 V181 R184 I208L123-L210 HydrophobicContact CD1-CD1 4.39Å; L123-L210 HydrophobicContact CD2-CD1 4.15Å; L124-L210 PolarHBondContact O-N 3.43Å; I125-L210 CarbonylContact C-O 3.55Å; I125-L210 WeakPolarHBondContact CA-O 3.3Å; I125-L210 HydrophobicContact CG1-CB 4.38Å; I125-L210 HydrophobicContact CG1-CD1 4.35Å; T126-L210 PolarHBondContact N-O 3.29Å; I161-L210 HydrophobicContact CG2-CD1 4.22Å; I161-L210 HydrophobicContact CG2-CD2 4.39Å; V165-L210 HydrophobicContact CG2-CD1 3.28Å; M180-L210 WeakPolarHBondContact O-CD2 3.32Å; V181-L210 HydrophobicContact CG2-CD2 4.36Å; R184-L210 HydrophobicContact CB-CD2 3.54Å; I208-L210 HydrophobicContact CG2-CD2 4.06Å; I208-L210 HydrophobicContact CG2-CG 4.29Å
211H95.7Very high90.9Very high61 Ų6139.6 Ų39.628%0.28220%0.203SC..EExtended strand (participates in β ladder)trans-114.4119.4176.7-168.144.8000110.6T126 M180 N213T126-H211 CarbonylContact O-C 3.5Å; T126-H211 WeakPolarHBondContact O-CA 3.46Å; T126-H211 PolarHBondContact O-ND1 2.96Å; T126-H211 PolarHBondContact OG1-ND1 2.83Å; M180-H211 VanDerWaalsContact CG-O 3.3Å; M180-H211 WeakPolarHBondContact CG-O 3.49Å; H211-N213 PolarHBondContact CD2-OD1 3.09Å; H211-N213 PolarHBondContact O-N 3.02Å
212D93.4Very high90.3Very high4 Ų444.6 Ų44.62%0.02123%0.23CC..EExtended strand (participates in β ladder)trans-77.4104.9172.3-177.74.3000109.7T126 M180 S214 G217 C218 F219T126-D212 PolarHBondContact O-N 3.39Å; M180-D212 HydrophobicContact SD-CB 4.02Å; D212-S214 VanDerWaalsContact C-N 3.34Å; D212-S214 VanDerWaalsContact CG-OG 3.29Å; D212-S214 VanDerWaalsContact OD1-CB 3.24Å; D212-S214 WeakPolarHBondContact OD1-CB 3.19Å; D212-S214 PolarHBondContact OD1-N 3.47Å; D212-S214 PolarHBondContact OD1-OG 3.4Å; D212-S214 PolarHBondContact OD2-OG 2.87Å; D212-G217 WeakPolarHBondContact OD2-CA 3.43Å; D212-C218 PolarHBondContact OD2-N 2.8Å; D212-F219 HydrophobicContact CB-CD2 4.24Å; D212-F219 HydrophobicContact CB-CE2 4.18Å
213N87.9Confident89.8Confident105 Ų10544.1 Ų44.156%0.56123%0.229SC*.  trans-88.64.8177.4-69.9-29.7000113.2H211H211-N213 PolarHBondContact CD2-OD1 3.09Å; H211-N213 PolarHBondContact O-N 3.02Å
214S83.4Confident89Confident25 Ų2548 Ų4818%0.17525%0.252CS..  trans-72.6138.2-179.465.40000111.3D212 R216 G217 C218D212-S214 VanDerWaalsContact C-N 3.34Å; D212-S214 VanDerWaalsContact CG-OG 3.29Å; D212-S214 VanDerWaalsContact OD1-CB 3.24Å; D212-S214 WeakPolarHBondContact OD1-CB 3.19Å; D212-S214 PolarHBondContact OD1-N 3.47Å; D212-S214 PolarHBondContact OD1-OG 3.4Å; D212-S214 PolarHBondContact OD2-OG 2.87Å; S214-R216 PolarHBondContact O-N 3.14Å; S214-R216 VanDerWaalsContact O-N 3.1Å; S214-G217 PolarHBondContact O-N 3.24Å; S214-G217 VanDerWaalsContact OG-CA 3.22Å; S214-G217 WeakPolarHBondContact OG-CA 3.46Å; S214-G217 PolarHBondContact OG-N 2.82Å; S214-C218 PolarHBondContact OG-N 3.39Å
215D72.9Confident88.5Confident170 Ų17046.5 Ų46.591%0.90925%0.245SC*.THydrogen-bonded Turntrans-59.3-27.6-175.9-64.4-36.6000113.6
216R73.9Confident87.9Confident249 Ų24950.1 Ų50.194%0.9427%0.27SS*.THydrogen-bonded Turntrans-110.9-2.6-176.7-63.4-173.9-179.2-176.80.7114.4S214S214-R216 PolarHBondContact O-N 3.14Å; S214-R216 VanDerWaalsContact O-N 3.1Å
217G80.2Confident87.2Confident18 Ų1855.3 Ų55.319%0.18629%0.293CS..  trans70.996.4-173.300000112.6D212 S214 F219 G220D212-G217 WeakPolarHBondContact OD2-CA 3.43Å; S214-G217 PolarHBondContact O-N 3.24Å; S214-G217 VanDerWaalsContact OG-CA 3.22Å; S214-G217 WeakPolarHBondContact OG-CA 3.46Å; S214-G217 PolarHBondContact OG-N 2.82Å; G217-F219 PolarHBondContact O-N 2.76Å; G217-G220 PolarHBondContact O-N 3.45Å; G217-G220 VanDerWaalsContact O-N 3.08Å
218C88.3Confident86.5Confident9 Ų957.5 Ų57.56%0.06131%0.306CS..THydrogen-bonded Turntrans-73-16.4-170.773.30000113.6Y171 C172 D212 S214 G220Y171-C218 CarbonylContact C-O 3.55Å; Y171-C218 WeakPolarHBondContact CA-O 3.43Å; Y171-C218 WeakPolarHBondContact CB-O 3.33Å; Y171-C218 PolarHBondContact N-O 2.55Å; C172-C218 HydrophobicContact CB-CB 3.71Å; C172-C218 WeakPolarHBondContact CB-SG 3.41Å; C172-C218 PolarHBondContact N-O 3.17Å; C172-C218 VanDerWaalsContact N-O 3.15Å; C172-C218 WeakPolarHBondContact SG-CB 3.37Å; C172-C218 PolarHBondContact SG-O 2.65Å; C172-C218 CovalentContact SG-SG 2.04Å; C172-C218 PolarHBondContact SG-SG 3.05Å; D212-C218 PolarHBondContact OD2-N 2.8Å; S214-C218 PolarHBondContact OG-N 3.39Å; C218-G220 VanDerWaalsContact C-N 3.26Å; C218-G220 PolarHBondContact O-N 3.18Å
219F90.5Very high85.5Confident0 Ų061.2 Ų61.20%033%0.331CS..THydrogen-bonded Turntrans-75.4-13.8172.1-68.1-85.5000113.5I125 I136 V165 L168 M180 D212 G217 P223 W235I125-F219 HydrophobicContact CD1-CE1 3.95Å; I125-F219 HydrophobicContact CD1-CZ 3.9Å; I125-F219 HydrophobicContact CG2-CD2 4.06Å; I125-F219 HydrophobicContact CG2-CE2 3.59Å; I125-F219 HydrophobicContact CG2-CZ 3.94Å; I136-F219 HydrophobicContact CD1-CB 3.99Å; I136-F219 HydrophobicContact CD1-CD1 4.05Å; I136-F219 HydrophobicContact CD1-CD2 4.22Å; I136-F219 HydrophobicContact CD1-CG 3.82Å; V165-F219 HydrophobicContact CG1-CE1 3.9Å; V165-F219 HydrophobicContact CG1-CZ 3.72Å; L168-F219 HydrophobicContact CB-CD1 4.41Å; L168-F219 HydrophobicContact CB-CE1 4.34Å; M180-F219 HydrophobicContact CE-CE2 3.71Å; M180-F219 HydrophobicContact CE-CZ 3.8Å; M180-F219 HydrophobicContact SD-CE2 3.82Å; M180-F219 HydrophobicContact SD-CZ 4.27Å; D212-F219 HydrophobicContact CB-CD2 4.24Å; D212-F219 HydrophobicContact CB-CE2 4.18Å; G217-F219 PolarHBondContact O-N 2.76Å; F219-P223 HydrophobicContact CB-CG 4.03Å; F219-W235 HydrophobicContact CB-CZ2 4.08Å; F219-W235 HydrophobicContact CD2-CZ2 4.4Å
220G87.2Confident84.7Confident9 Ų966.5 Ų66.59%0.09337%0.365CS..  trans70.8177.8-173.400000113.5G217 C218 W235G217-G220 PolarHBondContact O-N 3.45Å; G217-G220 VanDerWaalsContact O-N 3.08Å; C218-G220 VanDerWaalsContact C-N 3.26Å; C218-G220 PolarHBondContact O-N 3.18Å; G220-W235 PolarHBondContact O-NE1 2.98Å
221P85.4Confident84.1Confident94 Ų9468.6 Ų68.661%0.6137%0.373SS*.SBendtrans-71.9-34.2-174.627.2-34.1000113.8W235P221-W235 VanDerWaalsContact O-CD1 3.3Å
222D86.3Confident83.7Confident106 Ų10674.4 Ų74.457%0.56739%0.392SS*.SBendtrans-130.479-175.8-59.6-72.7000110.1Y233D222-Y233 WeakPolarHBondContact CA-O 3.46Å
223P86.9Confident83.6Confident1 Ų174.4 Ų74.41%0.00639%0.392CS..  trans-60.6140.4-179.2-19.130.5000111.1I136 F219 Y233I136-P223 HydrophobicContact CD1-CG 3.96Å; I136-P223 HydrophobicContact CG1-CG 4.46Å; I136-P223 HydrophobicContact CG2-CG 4.37Å; F219-P223 HydrophobicContact CB-CG 4.03Å; P223-Y233 VanDerWaalsContact O-CB 3.31Å; P223-Y233 WeakPolarHBondContact O-CB 3.38Å; P223-Y233 PolarHBondContact O-N 3.39Å; P223-Y233 VanDerWaalsContact O-N 3.15Å
224V80.3Confident83.7Confident81 Ų8173 Ų7349%0.49138%0.379SS..BIsolated β-bridgetrans-116136.1-178.5-177.70000109.8S226V224-S226 PolarHBondContact O-N 2.98Å
225H84.3Confident84.1Confident4 Ų474.1 Ų74.12%0.01938%0.379CS..  trans-73.8110170.6-157.1-70000110.4F149 K167 E227 V228 R231 Y233F149-H225 AromaticContact CD1-NE2 3.77Å; F149-H225 AromaticContact CE1-CD2 3.95Å; F149-H225 AromaticContact CE1-NE2 3.24Å; F149-H225 WeakPolarHBondContact CE1-NE2 3.33Å; K167-H225 WeakPolarHBondContact O-CA 3.47Å; H225-E227 VanDerWaalsContact C-N 3.26Å; H225-E227 PolarHBondContact ND1-N 2.76Å; H225-E227 VanDerWaalsContact ND1-N 3.17Å; H225-E227 PolarHBondContact O-N 2.99Å; H225-V228 HydrophobicContact CB-CB 4.25Å; H225-V228 WeakPolarHBondContact CB-O 3.25Å; H225-V228 PolarHBondContact ND1-N 2.86Å; H225-V228 VanDerWaalsContact ND1-N 3.12Å; H225-V228 CarbonylContact O-C 3.47Å; H225-V228 PolarHBondContact O-N 3.12Å; H225-V228 VanDerWaalsContact O-N 3.16Å; H225-R231 HydrophobicContact CB-CB 4.2Å; H225-Y233 HydrophobicContact CB-CE2 4Å
226S81.3Confident85Confident77 Ų7771.2 Ų71.254%0.53836%0.356SS..THydrogen-bonded Turntrans-51.3-40.1177.749.50000114.1K167 V224K167-S226 VanDerWaalsContact CA-OG 3.25Å; K167-S226 WeakPolarHBondContact CA-OG 3.33Å; K167-S226 WeakPolarHBondContact CB-OG 3.14Å; K167-S226 PolarHBondContact O-N 2.94Å; K167-S226 PolarHBondContact O-OG 2.67Å; V224-S226 PolarHBondContact O-N 2.98Å
227E81.7Confident86Confident120 Ų12063.3 Ų63.356%0.56133%0.334SS*.THydrogen-bonded Turntrans-92.7-13.8-179.1-55.1179.3155.400115.2K167 H225K167-E227 HydrophobicContact CD-CG 4.28Å; K167-E227 WeakPolarHBondContact CD-OE2 3.36Å; K167-E227 VanDerWaalsContact CE-OE1 3.3Å; K167-E227 WeakPolarHBondContact CE-OE1 3.32Å; K167-E227 WeakPolarHBondContact CE-OE2 3.29Å; K167-E227 IonicContact NZ-OE1 3.11Å; K167-E227 PolarHBondContact NZ-OE1 2.84Å; K167-E227 IonicContact NZ-OE2 3.79Å; K167-E227 PolarHBondContact NZ-OE2 2.98Å; H225-E227 VanDerWaalsContact C-N 3.26Å; H225-E227 PolarHBondContact ND1-N 2.76Å; H225-E227 VanDerWaalsContact ND1-N 3.17Å; H225-E227 PolarHBondContact O-N 2.99Å
228V83.2Confident86.6Confident46 Ų4662.7 Ų62.728%0.27933%0.327SS..  trans-137.470.5-176.6-168.10000108H225 T230 R231H225-V228 HydrophobicContact CB-CB 4.25Å; H225-V228 WeakPolarHBondContact CB-O 3.25Å; H225-V228 PolarHBondContact ND1-N 2.86Å; H225-V228 VanDerWaalsContact ND1-N 3.12Å; H225-V228 CarbonylContact O-C 3.47Å; H225-V228 PolarHBondContact O-N 3.12Å; H225-V228 VanDerWaalsContact O-N 3.16Å; V228-T230 PolarHBondContact O-N 3.32Å; V228-R231 HydrophobicContact CB-CG 4.25Å; V228-R231 HydrophobicContact CG1-CB 4.43Å; V228-R231 HydrophobicContact CG1-CG 3.76Å; V228-R231 WeakPolarHBondContact O-CB 3.42Å; V228-R231 PolarHBondContact O-N 3.11Å
229P77.3Confident86.8Confident89 Ų8965.5 Ų65.558%0.57835%0.345SS*.THydrogen-bonded Turntrans-60.6-17.4-169.8-24.635.4000114.2R231P229-R231 VanDerWaalsContact C-N 3.27Å; P229-R231 PolarHBondContact O-N 2.81Å
230T81.9Confident86.8Confident127 Ų12772.8 Ų72.878%0.77938%0.379SS*.THydrogen-bonded Turntrans-69.7-21.8173.355.20000113.1V228 R232V228-T230 PolarHBondContact O-N 3.32Å; T230-R232 PolarHBondContact O-N 2.79Å
231R84.9Confident87Confident46 Ų4678.7 Ų78.717%0.17441%0.413CS..  trans-82.4107171.8-68.6-173.7179.6174.30.8109.6E138 R148 H225 V228 P229 Y233E138-R231 WeakPolarHBondContact OE1-CG 3.3Å; E138-R231 IonicContact OE1-NE 3.61Å; R148-R231 PolarHBondContact O-NH1 2.87Å; R148-R231 VanDerWaalsContact O-NH1 3.17Å; H225-R231 HydrophobicContact CB-CB 4.2Å; V228-R231 HydrophobicContact CB-CG 4.25Å; V228-R231 HydrophobicContact CG1-CB 4.43Å; V228-R231 HydrophobicContact CG1-CG 3.76Å; V228-R231 WeakPolarHBondContact O-CB 3.42Å; V228-R231 PolarHBondContact O-N 3.11Å; P229-R231 VanDerWaalsContact C-N 3.27Å; P229-R231 PolarHBondContact O-N 2.81Å; R231-Y233 HydrophobicContact CB-CE2 4.07Å
232R85.8Confident87.4Confident182 Ų18276.3 Ų76.369%0.68740%0.397SS*.BIsolated β-bridgetrans-92.6139.8173.3-62.4-172.9176.1-171.5-1.6109.5E138 D139 T230E138-R232 CarbonylContact C-O 3.43Å; E138-R232 WeakPolarHBondContact CA-O 3.18Å; D139-R232 HydrophobicContact CB-CB 4.32Å; D139-R232 PolarHBondContact N-O 2.89Å; T230-R232 PolarHBondContact O-N 2.79Å
233Y91.2Very high87.9Confident4 Ų474.5 Ų74.52%0.01639%0.39CS..EExtended strand (participates in β ladder)trans-118.3153.4173.1-61.7-89.6000111I136 V137 E138 P147 L168 D222 P223 H225 R231I136-Y233 HydrophobicContact CG2-CD1 3.84Å; I136-Y233 HydrophobicContact CG2-CG 4.05Å; V137-Y233 VanDerWaalsContact C-CD1 3.49Å; V137-Y233 WeakPolarHBondContact O-CA 3.29Å; V137-Y233 WeakPolarHBondContact O-CD1 3.48Å; E138-Y233 HydrophobicContact CB-CD1 4.05Å; E138-Y233 HydrophobicContact CB-CE1 3.65Å; E138-Y233 HydrophobicContact CG-CE1 4.12Å; P147-Y233 HydrophobicContact CB-CD1 4.48Å; P147-Y233 HydrophobicContact CB-CE1 3.81Å; P147-Y233 HydrophobicContact CG-CD1 3.9Å; P147-Y233 HydrophobicContact CG-CE1 3.68Å; L168-Y233 HydrophobicContact CD2-CD2 3.85Å; L168-Y233 HydrophobicContact CD2-CE1 4.46Å; L168-Y233 HydrophobicContact CD2-CE2 3.41Å; L168-Y233 VanDerWaalsContact CD2-CE2 3.41Å; D222-Y233 WeakPolarHBondContact CA-O 3.46Å; P223-Y233 VanDerWaalsContact O-CB 3.31Å; P223-Y233 WeakPolarHBondContact O-CB 3.38Å; P223-Y233 PolarHBondContact O-N 3.39Å; P223-Y233 VanDerWaalsContact O-N 3.15Å; H225-Y233 HydrophobicContact CB-CE2 4Å; R231-Y233 HydrophobicContact CB-CE2 4.07Å
234R90.9Very high88.3Confident76 Ų7675.9 Ų75.929%0.28740%0.399SS..EExtended strand (participates in β ladder)trans-146.1157.717559.2-179.3168179.7-9.1110.9V137 D139V137-R234 HydrophobicContact CG2-CG 4.01Å; V137-R234 PolarHBondContact N-O 2.92Å; V137-R234 PolarHBondContact O-N 2.86Å; D139-R234 HydrophobicContact CB-CG 4.39Å; D139-R234 VanDerWaalsContact CG-CZ 3.4Å; D139-R234 IonicContact OD1-CZ 2.67Å; D139-R234 IonicContact OD1-NE 3.8Å; D139-R234 PolarHBondContact OD1-NE 2.8Å; D139-R234 IonicContact OD1-NH1 3.48Å; D139-R234 IonicContact OD1-NH2 3.92Å; D139-R234 PolarHBondContact OD1-NH2 2.82Å; D139-R234 IonicContact OD2-CZ 3.82Å; D139-R234 IonicContact OD2-NE 3.05Å; D139-R234 IonicContact OD2-NH1 2.62Å; D139-R234 IonicContact OD2-NH2 3.39Å
235W91.6Very high89.1Confident48 Ų4877.3 Ų77.318%0.18240%0.395CS..EExtended strand (participates in β ladder)trans-78.1136.1170.6-67.694.3000111.5I125 S127 K134 F135 I136 F219 G220 P221I125-W235 HydrophobicContact CG2-CH2 4.32Å; S127-W235 VanDerWaalsContact CB-CH2 3.48Å; K134-W235 HydrophobicContact CB-CB 4.41Å; K134-W235 HydrophobicContact CB-CD2 4.44Å; K134-W235 HydrophobicContact CB-CE3 3.66Å; K134-W235 HydrophobicContact CB-CZ3 4.33Å; F135-W235 CarbonylContact O-C 3.58Å; F135-W235 WeakPolarHBondContact O-CA 3.05Å; I136-W235 HydrophobicContact CD1-CH2 3.91Å; I136-W235 HydrophobicContact CD1-CZ2 3.72Å; I136-W235 HydrophobicContact CD1-CZ3 4.48Å; I136-W235 HydrophobicContact CG1-CD2 3.87Å; I136-W235 HydrophobicContact CG1-CE3 3.84Å; I136-W235 HydrophobicContact CG1-CH2 3.66Å; I136-W235 HydrophobicContact CG1-CZ2 3.66Å; I136-W235 HydrophobicContact CG1-CZ3 3.73Å; F219-W235 HydrophobicContact CB-CZ2 4.08Å; F219-W235 HydrophobicContact CD2-CZ2 4.4Å; G220-W235 PolarHBondContact O-NE1 2.98Å; P221-W235 VanDerWaalsContact O-CD1 3.3Å
236R92.7Very high89.6Confident110 Ų11080.5 Ų80.542%0.41541%0.413SS..EExtended strand (participates in β ladder)trans-122.5147.6169.5-70.5-64.5-164.11607.2109.9K134 F135 V137K134-R236 CarbonylContact C-O 3.51Å; K134-R236 WeakPolarHBondContact CA-O 3.4Å; F135-R236 HydrophobicContact CD1-CB 4.26Å; F135-R236 WeakPolarHBondContact CD1-O 3.12Å; F135-R236 HydrophobicContact CE1-CB 3.71Å; F135-R236 HydrophobicContact CZ-CB 3.86Å; F135-R236 PolarHBondContact N-O 3Å; F135-R236 PolarHBondContact O-N 2.74Å; V137-R236 HydrophobicContact CG1-CG 4.42Å; V137-R236 HydrophobicContact CG2-CB 4.4Å; V137-R236 HydrophobicContact CG2-CG 3.5Å; V137-R236 VanDerWaalsContact CG2-CG 3.5Å
237V93.5Very high90.2Very high82 Ų8277.9 Ų77.950%0.49739%0.392SS..EExtended strand (participates in β ladder)trans-77.6129.8175.7178.30000108.8T132 K134T132-V237 HydrophobicContact CG2-CG1 4.47Å; K134-V237 HydrophobicContact CG-CG2 4.23Å
238L93.8Very high90.9Very high6 Ų672.2 Ų72.23%0.03137%0.365CS..PPolyproline II helixtrans-79.6132.3170.5-169.369.1000108.9T133 F135 H240 T242 P244 F247T133-L238 HydrophobicContact CG2-CB 4.43Å; T133-L238 HydrophobicContact CG2-CD2 4.28Å; T133-L238 WeakPolarHBondContact O-CB 3.37Å; T133-L238 PolarHBondContact O-N 2.94Å; F135-L238 HydrophobicContact CD1-CB 4.01Å; F135-L238 HydrophobicContact CD1-CD1 4.19Å; F135-L238 HydrophobicContact CE1-CB 4.28Å; F135-L238 HydrophobicContact CE1-CD1 4.09Å; L238-H240 PolarHBondContact O-N 3.26Å; L238-T242 HydrophobicContact CD1-CG2 4.5Å; L238-T242 VanDerWaalsContact CD2-O 3.27Å; L238-T242 WeakPolarHBondContact CD2-O 3.47Å; L238-P244 HydrophobicContact CD2-CB 4.47Å; L238-P244 HydrophobicContact CD2-CG 3.89Å; L238-F247 HydrophobicContact CD1-CB 3.75Å; L238-F247 HydrophobicContact CD1-CD1 4.09Å; L238-F247 HydrophobicContact CD1-CD2 3.89Å; L238-F247 HydrophobicContact CD1-CG 3.63Å
239P92.8Very high91.3Very high68 Ų6876.5 Ų76.544%0.44238%0.376SS..PPolyproline II helixtrans-56.7138.3176.1-24.934.6000111.9T241 T242P239-T241 PolarHBondContact O-N 3.3Å; P239-T242 PolarHBondContact O-N 3.07Å
240H89.7Confident92Very high153 Ų15376.8 Ų76.871%0.70837%0.372SS*.THydrogen-bonded Turntrans-59.8-22.1179.5-62.5-61.3000113.7L238 T242L238-H240 PolarHBondContact O-N 3.26Å; H240-T242 VanDerWaalsContact C-N 3.3Å
241T92.5Very high92.7Very high133 Ų13371.7 Ų71.782%0.81634%0.339SS*.THydrogen-bonded Turntrans-84.61.2177.555.90000113.5P239P239-T241 PolarHBondContact O-N 3.3Å
242T93.4Very high93.1Very high44 Ų4469.8 Ų69.827%0.2733%0.334SS..SBendtrans-129.2124.8-174.2-56.40000110.6L238 P239 H240 D246 F247L238-T242 HydrophobicContact CD1-CG2 4.5Å; L238-T242 VanDerWaalsContact CD2-O 3.27Å; L238-T242 WeakPolarHBondContact CD2-O 3.47Å; P239-T242 PolarHBondContact O-N 3.07Å; H240-T242 VanDerWaalsContact C-N 3.3Å; T242-D246 HydrophobicContact CG2-CB 4.25Å; T242-F247 HydrophobicContact CG2-CB 3.9Å
243T95.4Very high93.2Very high67 Ų6763.1 Ų63.141%0.41131%0.311SS..  trans-76.5154.3173.9740000110.8R245 D246 F247T243-R245 PolarHBondContact O-N 3.36Å; T243-R245 VanDerWaalsContact O-N 3.16Å; T243-D246 PolarHBondContact O-N 3.09Å; T243-D246 VanDerWaalsContact O-N 3.14Å; T243-D246 PolarHBondContact OG1-N 3.49Å; T243-D246 VanDerWaalsContact OG1-N 3.08Å; T243-D246 PolarHBondContact OG1-OD2 2.92Å; T243-F247 PolarHBondContact O-N 2.75Å
244P96Very high92.6Very high30 Ų3067 Ų6720%0.19534%0.339CS..Hα-helixtrans-52.7-35.6172.3-29.937.4000113L124 T126 Y187 L238 A248L124-P244 HydrophobicContact CD2-CB 3.9Å; L124-P244 WeakPolarHBondContact CD2-O 3.17Å; T126-P244 HydrophobicContact CG2-CB 4.31Å; T126-P244 HydrophobicContact CG2-CG 4.39Å; Y187-P244 HydrophobicContact CE2-CB 3.86Å; L238-P244 HydrophobicContact CD2-CB 4.47Å; L238-P244 HydrophobicContact CD2-CG 3.89Å; P244-A248 WeakPolarHBondContact O-CB 3.33Å; P244-A248 PolarHBondContact O-N 2.89Å
245R96.4Very high91.4Very high111 Ų11169.1 Ų69.142%0.41936%0.356SS..Hα-helixtrans-66.4-47.3177.5-177.4179.3-72.1-141.7-0.3112.2Y187 T243 F247 A248 R249Y187-R245 HydrophobicContact CD1-CB 4.26Å; Y187-R245 HydrophobicContact CD1-CG 4.13Å; Y187-R245 HydrophobicContact CD2-CB 4.11Å; Y187-R245 HydrophobicContact CD2-CG 4.5Å; Y187-R245 HydrophobicContact CE1-CB 4.13Å; Y187-R245 HydrophobicContact CE1-CG 4.41Å; Y187-R245 HydrophobicContact CE2-CB 3.96Å; Y187-R245 HydrophobicContact CG-CB 4.25Å; Y187-R245 HydrophobicContact CG-CG 4.18Å; T243-R245 PolarHBondContact O-N 3.36Å; T243-R245 VanDerWaalsContact O-N 3.16Å; R245-F247 VanDerWaalsContact C-N 3.3Å; R245-F247 PolarHBondContact O-N 2.93Å; R245-A248 PolarHBondContact O-N 2.96Å; R245-R249 WeakPolarHBondContact O-CG 3.06Å; R245-R249 PolarHBondContact O-N 2.97Å
246D95Very high89.8Confident72 Ų7278.2 Ų78.239%0.38540%0.396SS..Hα-helixtrans-66.7-37179.7-62-41.7000111.5T242 T243 R249T242-D246 HydrophobicContact CG2-CB 4.25Å; T243-D246 PolarHBondContact O-N 3.09Å; T243-D246 VanDerWaalsContact O-N 3.14Å; T243-D246 PolarHBondContact OG1-N 3.49Å; T243-D246 VanDerWaalsContact OG1-N 3.08Å; T243-D246 PolarHBondContact OG1-OD2 2.92Å; D246-R249 PolarHBondContact O-N 3.03Å; D246-R249 IonicContact OD1-NH1 2.62Å; D246-R249 PolarHBondContact OD1-NH1 2.05Å
247F95.1Very high89.6Confident22 Ų2276.7 Ų76.710%0.09640%0.395CS..Hα-helixtrans-63.6-44.3173.3-175.5-105.4000112.5L124 F135 I144 L146 L238 T242 T243 R245 R249 I250 F251L124-F247 HydrophobicContact CD1-CD1 4.16Å; L124-F247 HydrophobicContact CD1-CE1 4.4Å; F135-F247 HydrophobicContact CD2-CD1 4.41Å; F135-F247 AromaticContact CD2-CE1 3.64Å; F135-F247 HydrophobicContact CD2-CE1 3.64Å; F135-F247 HydrophobicContact CD2-CZ 4.21Å; F135-F247 HydrophobicContact CE1-CE1 4.47Å; F135-F247 HydrophobicContact CE1-CZ 4.4Å; F135-F247 HydrophobicContact CE2-CD1 4.19Å; F135-F247 AromaticContact CE2-CE1 3.15Å; F135-F247 HydrophobicContact CE2-CE1 3.15Å; F135-F247 HydrophobicContact CE2-CE2 4.35Å; F135-F247 AromaticContact CE2-CZ 3.26Å; F135-F247 HydrophobicContact CE2-CZ 3.26Å; F135-F247 HydrophobicContact CG-CE1 4.45Å; F135-F247 AromaticContact CZ-CE1 3.66Å; F135-F247 HydrophobicContact CZ-CE1 3.66Å; F135-F247 HydrophobicContact CZ-CE2 4.1Å; F135-F247 AromaticContact CZ-CZ 3.4Å; F135-F247 HydrophobicContact CZ-CZ 3.4Å; I144-F247 HydrophobicContact CG2-CZ 4.44Å; L146-F247 HydrophobicContact CD2-CE1 4.22Å; L238-F247 HydrophobicContact CD1-CB 3.75Å; L238-F247 HydrophobicContact CD1-CD1 4.09Å; L238-F247 HydrophobicContact CD1-CD2 3.89Å; L238-F247 HydrophobicContact CD1-CG 3.63Å; T242-F247 HydrophobicContact CG2-CB 3.9Å; T243-F247 PolarHBondContact O-N 2.75Å; R245-F247 VanDerWaalsContact C-N 3.3Å; R245-F247 PolarHBondContact O-N 2.93Å; F247-R249 VanDerWaalsContact C-N 3.25Å; F247-R249 PolarHBondContact O-N 3.46Å; F247-I250 HydrophobicContact CD2-CD1 3.94Å; F247-I250 HydrophobicContact CE2-CD1 4.31Å; F247-I250 WeakPolarHBondContact O-CB 3.34Å; F247-I250 WeakPolarHBondContact O-CG1 3.44Å; F247-I250 PolarHBondContact O-N 2.96Å; F247-I250 VanDerWaalsContact O-N 3.15Å; F247-F251 HydrophobicContact CD1-CE2 4.05Å; F247-F251 AromaticContact CE1-CE2 3.51Å; F247-F251 HydrophobicContact CE1-CE2 3.51Å; F247-F251 HydrophobicContact CE1-CZ 4.01Å; F247-F251 HydrophobicContact CE2-CE2 4.32Å; F247-F251 AromaticContact CZ-CE2 3.66Å; F247-F251 HydrophobicContact CZ-CE2 3.66Å; F247-F251 AromaticContact CZ-CZ 3.84Å; F247-F251 HydrophobicContact CZ-CZ 3.84Å
248A95.4Very high89.4Confident0 Ų076.4 Ų76.40%039%0.39CS..Hα-helixtrans-57.9-37.6178.400000112.7L124 Y187 I207 P244 R245 I250 F251L124-A248 HydrophobicContact CD2-CB 4.06Å; Y187-A248 HydrophobicContact CD2-CB 3.76Å; Y187-A248 HydrophobicContact CG-CB 4.36Å; I207-A248 VanDerWaalsContact CD1-O 3.24Å; I207-A248 WeakPolarHBondContact CD1-O 3.25Å; I207-A248 HydrophobicContact CG2-CB 3.9Å; P244-A248 WeakPolarHBondContact O-CB 3.33Å; P244-A248 PolarHBondContact O-N 2.89Å; R245-A248 PolarHBondContact O-N 2.96Å; A248-I250 PolarHBondContact O-N 2.95Å; A248-I250 VanDerWaalsContact O-N 3.11Å; A248-F251 PolarHBondContact O-N 3.24Å
249R92.5Very high89.2Confident136 Ų13680.3 Ų80.351%0.51341%0.41SS..Hα-helixtrans-60.2-22.4179.9-72169.5171.2169.6-12.6113.6R245 D246 F247 F251 G252R245-R249 WeakPolarHBondContact O-CG 3.06Å; R245-R249 PolarHBondContact O-N 2.97Å; D246-R249 PolarHBondContact O-N 3.03Å; D246-R249 IonicContact OD1-NH1 2.62Å; D246-R249 PolarHBondContact OD1-NH1 2.05Å; F247-R249 VanDerWaalsContact C-N 3.25Å; F247-R249 PolarHBondContact O-N 3.46Å; R249-F251 PolarHBondContact O-N 3.14Å; R249-G252 PolarHBondContact O-N 3.24Å
250I92.5Very high88.9Confident95 Ų9581 Ų8149%0.48741%0.408SS..THydrogen-bonded Turntrans-61.5-30.8175.6-60171.6000111.1K193 F247 A248K193-I250 WeakPolarHBondContact CD-O 3.5Å; K193-I250 WeakPolarHBondContact CE-O 3.43Å; K193-I250 PolarHBondContact NZ-O 2.86Å; F247-I250 HydrophobicContact CD2-CD1 3.94Å; F247-I250 HydrophobicContact CE2-CD1 4.31Å; F247-I250 WeakPolarHBondContact O-CB 3.34Å; F247-I250 WeakPolarHBondContact O-CG1 3.44Å; F247-I250 PolarHBondContact O-N 2.96Å; F247-I250 VanDerWaalsContact O-N 3.15Å; A248-I250 PolarHBondContact O-N 2.95Å; A248-I250 VanDerWaalsContact O-N 3.11Å
251F94.8Very high88.9Confident21 Ų2176.5 Ų76.59%0.09239%0.389CS..THydrogen-bonded Turntrans-90.7-3.8-176.4-58.7-87.7000113.9Y122 I144 L146 K193 I207 F247 A248 R249Y122-F251 HydrophobicContact CD2-CB 4.23Å; Y122-F251 HydrophobicContact CE2-CB 4.36Å; I144-F251 HydrophobicContact CG2-CZ 4.13Å; L146-F251 HydrophobicContact CD1-CB 4.26Å; L146-F251 HydrophobicContact CD1-CD1 4.41Å; L146-F251 HydrophobicContact CD1-CD2 3.67Å; L146-F251 HydrophobicContact CD1-CE2 4.1Å; L146-F251 HydrophobicContact CD1-CG 3.85Å; L146-F251 HydrophobicContact CD2-CD2 4.5Å; L146-F251 HydrophobicContact CD2-CE2 4.09Å; L146-F251 HydrophobicContact CD2-CZ 4.21Å; L146-F251 HydrophobicContact CG-CD1 4.1Å; L146-F251 HydrophobicContact CG-CD2 3.91Å; L146-F251 HydrophobicContact CG-CE1 4.08Å; L146-F251 HydrophobicContact CG-CE2 3.9Å; L146-F251 HydrophobicContact CG-CG 4.01Å; L146-F251 HydrophobicContact CG-CZ 3.99Å; K193-F251 PolarHBondContact N-O 2.86Å; I207-F251 HydrophobicContact CD1-CB 3.93Å; F247-F251 HydrophobicContact CD1-CE2 4.05Å; F247-F251 AromaticContact CE1-CE2 3.51Å; F247-F251 HydrophobicContact CE1-CE2 3.51Å; F247-F251 HydrophobicContact CE1-CZ 4.01Å; F247-F251 HydrophobicContact CE2-CE2 4.32Å; F247-F251 AromaticContact CZ-CE2 3.66Å; F247-F251 HydrophobicContact CZ-CE2 3.66Å; F247-F251 AromaticContact CZ-CZ 3.84Å; F247-F251 HydrophobicContact CZ-CZ 3.84Å; A248-F251 PolarHBondContact O-N 3.24Å; R249-F251 PolarHBondContact O-N 3.14Å
252G93.9Very high88.7Confident6 Ų672.7 Ų72.76%0.06236%0.361CS..EExtended strand (participates in β ladder)trans-117.3164.8178.200000112.7Y191 K193 R249Y191-G252 CarbonylContact O-C 3.57Å; Y191-G252 VanDerWaalsContact O-CA 3.26Å; Y191-G252 WeakPolarHBondContact O-CA 3.47Å; K193-G252 WeakPolarHBondContact CE-O 3.48Å; R249-G252 PolarHBondContact O-N 3.24Å
253I88.7Confident88.3Confident42 Ų4274.8 Ų74.822%0.21537%0.367CS..EExtended strand (participates in β ladder)trans-129.7118.1161.7-56.1176.9000106.7Y101 E102 H188 Y191 K193Y101-I253 HydrophobicContact CD1-CB 4.37Å; Y101-I253 HydrophobicContact CD1-CG2 4.14Å; E102-I253 HydrophobicContact CG-CD1 4.43Å; H188-I253 PolarHBondContact CE1-O 2.54Å; Y191-I253 WeakPolarHBondContact CB-O 3.11Å; Y191-I253 HydrophobicContact CD1-CB 3.81Å; Y191-I253 HydrophobicContact CD1-CD1 3.65Å; Y191-I253 HydrophobicContact CD1-CG1 3.73Å; Y191-I253 HydrophobicContact CE1-CD1 3.63Å; Y191-I253 HydrophobicContact CE1-CG1 4.17Å; Y191-I253 HydrophobicContact CG-CB 4.31Å; Y191-I253 PolarHBondContact O-N 2.78Å; K193-I253 HydrophobicContact CD-CG1 4.47Å; K193-I253 VanDerWaalsContact CE-CG1 3.47Å; K193-I253 HydrophobicContact CG-CD1 4.37Å; K193-I253 HydrophobicContact CG-CG1 4.18Å
254S78.8Confident87.8Confident86 Ų8675.4 Ų75.460%0.60136%0.364SS*.  trans-75141.1168.5-57.30000108.7K256S254-K256 PolarHBondContact O-N 3.31Å
255L64.7Low87.1Confident120 Ų12079.2 Ų79.263%0.62838%0.378SS*.  trans-56.2136167.3-79.5163.5000108.1Y101Y101-L255 HydrophobicContact CD1-CD2 4.15Å; Y101-L255 HydrophobicContact CE1-CD1 4.48Å; Y101-L255 HydrophobicContact CE1-CD2 3.47Å; Y101-L255 VanDerWaalsContact CE1-CD2 3.47Å; Y101-L255 HydrophobicContact CE1-CG 3.56Å
256K57.5Low86.3Confident239 Ų23976.3 Ų76.3100%1.03938%0.375SS*.  trans-650165.6-74.6-178.6-176.31730109.6D67 S254D67-K256 IonicContact OD2-NZ 2.98Å; D67-K256 PolarHBondContact OD2-NZ 3.48Å; S254-K256 PolarHBondContact O-N 3.31Å

Retrieved 256 of 256 residues in 430.5 ms (Link to these results)