A0A077Z3K8_TRITR Loading...

Semaphorin-2A

AlphaFold DB , UniProt , Accession A0A077Z3K8, Species TRITR (Trichuris trichiura, Whipworm), Gene n/a, Length 723 aa.

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Site Residue pLDDT pLDDT confidence pLDDT10 pLDDT10 confidence SASA SASA [Ų] SASA10 SASA10 [Ų] RSA RSA unformatted RSA10 RSA10 unformatted Surface Surface10 (not used) Disorder (not used) Disorder Sec. str. Secondary structure Isomer Phi (φ) Psi (ψ) Omega (ω) Chi 1 (χ1) Chi 2 (χ2) Chi 3 (χ3) Chi 4 (χ4) Chi 5 (χ5) Tau (τ) Contacts (colored by PAE) Contact details
1M33.3Very low36Very low241 Ų241121.1 Ų121.1100%1.18767%0.667SS**  0-11.40-74.5-177.9-17300114.9
2A33.5Very low36.8Very low96 Ų96113.7 Ų113.779%0.79363%0.629SS**G310 helixtrans-82.7-6-17900000115.9
3Q32.5Very low37.9Very low168 Ų168112.2 Ų112.279%0.78562%0.617SS**G310 helixtrans-83.3-12.7-172-92.1177.3-25.300116
4F34.8Very low39.7Very low182 Ų182112.5 Ų112.580%0.79861%0.61SS**G310 helixtrans-94.8-4.1-176.6-78.6-80.6000114.7
5G32.4Very low42.2Very low53 Ų53108.9 Ų108.955%0.54659%0.587SS.*SBendtrans-88.2-11.6179.800000115.3
6E32.8Very low45.3Very low146 Ų146104.6 Ų104.668%0.68256%0.56SS**SBendtrans-82.6-16.7-176.6-78.8-176.5159.600113.7C8 L9 S10E6-C8 VanDerWaalsContact C-N 3.31Å; E6-C8 PolarHBondContact O-N 3.41Å; E6-L9 PolarHBondContact O-N 3.07Å; E6-S10 VanDerWaalsContact O-CB 3.24Å; E6-S10 WeakPolarHBondContact O-CB 3Å; E6-S10 PolarHBondContact O-N 3.49Å; E6-S10 PolarHBondContact O-OG 3.01Å; E6-S10 VanDerWaalsContact O-OG 3.11Å
7H36Very low48.1Very low126 Ų126102.3 Ų102.358%0.58354%0.544SS*.THydrogen-bonded Turntrans-64.3-25.3-173-87.6-39.8000115.8S10H7-S10 WeakPolarHBondContact CA-OG 3.38Å; H7-S10 PolarHBondContact O-OG 3.38Å
8C42.6Very low50.7Low49 Ų4996.9 Ų96.933%0.33152%0.515SS..THydrogen-bonded Turntrans-91.8-9.6-179.6-510000113.4E6 C471 F473E6-C8 VanDerWaalsContact C-N 3.31Å; E6-C8 PolarHBondContact O-N 3.41Å; C8-C471 HydrophobicContact CB-CB 4.26Å; C8-C471 WeakPolarHBondContact CB-SG 3.15Å; C8-C471 WeakPolarHBondContact SG-CB 3.29Å; C8-C471 CovalentContact SG-SG 2.08Å; C8-C471 PolarHBondContact SG-SG 2.72Å; C8-F473 HydrophobicContact CB-CE1 4.43Å; C8-F473 HydrophobicContact CB-CE2 4.48Å; C8-F473 HydrophobicContact CB-CZ 3.8Å
9L38.2Very low53Low152 Ų15294.1 Ų94.180%0.79650%0.503SS*.THydrogen-bonded Turntrans-115.2-22174.7-75.6169.6000113.2E6 S11E6-L9 PolarHBondContact O-N 3.07Å; L9-S11 PolarHBondContact O-N 3.26Å
10S37.9Very low55.1Low49 Ų4994.6 Ų94.634%0.34350%0.501SS..SBendtrans-59.9130.7165.765.20000107.4E6 H7E6-S10 VanDerWaalsContact O-CB 3.24Å; E6-S10 WeakPolarHBondContact O-CB 3Å; E6-S10 PolarHBondContact O-N 3.49Å; E6-S10 PolarHBondContact O-OG 3.01Å; E6-S10 VanDerWaalsContact O-OG 3.11Å; H7-S10 WeakPolarHBondContact CA-OG 3.38Å; H7-S10 PolarHBondContact O-OG 3.38Å
11S42.6Very low56.9Low70 Ų7091.7 Ų91.749%0.4949%0.494SS..  trans-43.9125.117573.10000107.9L9 I13L9-S11 PolarHBondContact O-N 3.26Å; S11-I13 PolarHBondContact O-N 3.41Å; S11-I13 VanDerWaalsContact O-N 3.11Å
12P45.4Very low59.8Low32 Ų3285.2 Ų85.221%0.20846%0.459CS..  trans-51.5130.2-177.610.1-17.9000107.3K14P12-K14 WeakPolarHBondContact O-CA 3.33Å; P12-K14 WeakPolarHBondContact O-CG 3.03Å; P12-K14 PolarHBondContact O-N 3.36Å
13I50.1Low62.8Low94 Ų9482.3 Ų82.348%0.48243%0.43SS..  trans-47.1106.6177.6-65.2171.1000106.1S11 H15 R16S11-I13 PolarHBondContact O-N 3.41Å; S11-I13 VanDerWaalsContact O-N 3.11Å; I13-H15 PolarHBondContact O-N 3.2Å; I13-H15 VanDerWaalsContact O-N 3.08Å; I13-R16 HydrophobicContact CG2-CG 4.05Å
14K63.7Low65.9Low117 Ų11776.6 Ų76.651%0.50940%0.402SS..SBendtrans-66.2-21.3-158.8-68.7-176.1177.3-177.40113P12P12-K14 WeakPolarHBondContact O-CA 3.33Å; P12-K14 WeakPolarHBondContact O-CG 3.03Å; P12-K14 PolarHBondContact O-N 3.36Å
15H78Confident68.9Low59 Ų5967.9 Ų67.927%0.27336%0.364SS..EExtended strand (participates in β ladder)trans-149.6123.2-174.9-175.3-84.8000108.2I13 P454 S496 L498I13-H15 PolarHBondContact O-N 3.2Å; I13-H15 VanDerWaalsContact O-N 3.08Å; H15-P454 WeakPolarHBondContact CE1-CG 3.32Å; H15-P454 WeakPolarHBondContact NE2-CG 3.05Å; H15-S496 WeakPolarHBondContact NE2-CB 3.11Å; H15-S496 PolarHBondContact NE2-OG 3.48Å; H15-L498 WeakPolarHBondContact CD2-CD2 3.15Å
16R90.6Very high71.9Confident40 Ų4066.9 Ų66.915%0.15134%0.343CS..EExtended strand (participates in β ladder)trans-113.7149.2167.9-72.8165.5178.4162.4-5.9107.8I13 E51 N52 V53 N54 S496 Q497I13-R16 HydrophobicContact CG2-CG 4.05Å; R16-E51 PolarHBondContact NH1-O 3.32Å; R16-N52 VanDerWaalsContact CD-OD1 3.31Å; R16-N52 WeakPolarHBondContact CD-OD1 3.43Å; R16-N52 PolarHBondContact NE-OD1 2.92Å; R16-V53 HydrophobicContact CB-CG2 3.78Å; R16-N54 WeakPolarHBondContact CB-OD1 3.41Å; R16-S496 CarbonylContact O-C 3.48Å; R16-S496 WeakPolarHBondContact O-CA 3.46Å; R16-Q497 HydrophobicContact CB-CB 4.06Å; R16-Q497 PolarHBondContact N-O 2.87Å; R16-Q497 VanDerWaalsContact N-O 3.08Å; R16-Q497 PolarHBondContact O-N 2.86Å
17F93.1Very high74.9Confident65 Ų6561 Ų6129%0.28532%0.317SS..EExtended strand (participates in β ladder)trans-146.4123-171.3-173-112.5000110.9S19 N54 I493 V495F17-S19 VanDerWaalsContact CE1-CB 3.42Å; F17-N54 VanDerWaalsContact C-OD1 3.3Å; F17-N54 PolarHBondContact N-OD1 3.35Å; F17-N54 PolarHBondContact O-OD1 2.72Å; F17-I493 HydrophobicContact CZ-CG2 4.17Å; F17-V495 WeakPolarHBondContact CA-O 3.46Å; F17-V495 WeakPolarHBondContact CD2-O 3.33Å
18F95.2Very high77.8Confident5 Ų555.7 Ų55.72%0.02229%0.293CS..EExtended strand (participates in β ladder)trans-103.4128.9171.6175.7-99.7000110.2K20 Y25 Y46 L48 V53 T56 F63 G494 V495F18-K20 HydrophobicContact CE2-CG 4.3Å; F18-K20 HydrophobicContact CZ-CG 3.84Å; F18-Y25 HydrophobicContact CD1-CE1 4.27Å; F18-Y25 AromaticContact CE1-CE1 3.89Å; F18-Y25 HydrophobicContact CE1-CE1 3.89Å; F18-Y46 HydrophobicContact CE1-CD1 4.15Å; F18-Y46 HydrophobicContact CE1-CD2 4.15Å; F18-Y46 HydrophobicContact CE1-CE1 4.27Å; F18-Y46 HydrophobicContact CE1-CE2 4.29Å; F18-Y46 HydrophobicContact CE1-CG 4.09Å; F18-Y46 AromaticContact CZ-CD1 3.76Å; F18-Y46 HydrophobicContact CZ-CD1 3.76Å; F18-Y46 AromaticContact CZ-CE1 3.77Å; F18-Y46 HydrophobicContact CZ-CE1 3.77Å; F18-Y46 HydrophobicContact CZ-CG 4.17Å; F18-L48 HydrophobicContact CB-CD1 4.02Å; F18-L48 HydrophobicContact CD1-CD1 3.62Å; F18-L48 HydrophobicContact CD1-CD2 4.01Å; F18-L48 HydrophobicContact CD1-CG 4.46Å; F18-L48 HydrophobicContact CD2-CD2 4Å; F18-L48 HydrophobicContact CE1-CD1 4.2Å; F18-L48 HydrophobicContact CE1-CD2 3.89Å; F18-L48 HydrophobicContact CE2-CD2 3.9Å; F18-L48 HydrophobicContact CG-CD1 3.79Å; F18-L48 HydrophobicContact CG-CD2 4.05Å; F18-L48 HydrophobicContact CZ-CD2 3.84Å; F18-V53 HydrophobicContact CB-CB 4.26Å; F18-V53 HydrophobicContact CB-CG2 4.42Å; F18-T56 HydrophobicContact CD2-CG2 3.98Å; F18-T56 HydrophobicContact CE2-CG2 3.7Å; F18-F63 AromaticContact CE2-CE2 3.84Å; F18-F63 HydrophobicContact CE2-CE2 3.84Å; F18-F63 HydrophobicContact CE2-CZ 4.39Å; F18-F63 HydrophobicContact CZ-CE2 4.11Å; F18-G494 CarbonylContact O-C 3.49Å; F18-G494 WeakPolarHBondContact O-CA 3.14Å; F18-V495 PolarHBondContact N-O 2.93Å; F18-V495 PolarHBondContact O-N 2.8Å
19S95Very high80.3Confident43 Ų4355 Ų5530%0.30129%0.286SS..  trans-154.7144.6171.8178.80000110.5F17 G21 I493F17-S19 VanDerWaalsContact CE1-CB 3.42Å; S19-G21 PolarHBondContact OG-N 3.08Å; S19-G21 VanDerWaalsContact OG-N 3.1Å; S19-G21 PolarHBondContact OG-O 3.32Å; S19-I493 VanDerWaalsContact CB-O 3.22Å; S19-I493 WeakPolarHBondContact CB-O 3.35Å; S19-I493 PolarHBondContact OG-O 2.82Å
20K94.9Very high82.9Confident104 Ų10449.1 Ų49.145%0.45226%0.255SS..SBendtrans-121.325.9169-65.8-74.5-1721650110.4F18 L23 Y25 Y46F18-K20 HydrophobicContact CE2-CG 4.3Å; F18-K20 HydrophobicContact CZ-CG 3.84Å; K20-L23 HydrophobicContact CB-CD1 3.96Å; K20-Y25 PolarHBondContact N-OH 3.21Å; K20-Y46 HydrophobicContact CG-CE1 4.43Å
21G92.7Very high85.3Confident35 Ų3547.2 Ų47.236%0.36124%0.241SC..SBendtrans104.9-174.5-172.500000112.4S19 L23 Y25S19-G21 PolarHBondContact OG-N 3.08Å; S19-G21 VanDerWaalsContact OG-N 3.1Å; S19-G21 PolarHBondContact OG-O 3.32Å; G21-L23 VanDerWaalsContact C-N 3.33Å; G21-L23 PolarHBondContact O-N 3.12Å; G21-Y25 WeakPolarHBondContact O-CE2 3.4Å
22K94.5Very high87.2Confident104 Ų10450.1 Ų50.145%0.45225%0.247SC..SBendtrans-77.583.9178.8-171.1174.8-178.5166.80110.4E457K22-E457 IonicContact NZ-OE1 3.96Å
23L96.6Very high88.9Confident36 Ų3655.8 Ų55.819%0.18827%0.271CS..  trans-10818.9-179.2-58.5-178.2000112.6K20 G21 Y25 A41 M42 D492K20-L23 HydrophobicContact CB-CD1 3.96Å; G21-L23 VanDerWaalsContact C-N 3.33Å; G21-L23 PolarHBondContact O-N 3.12Å; L23-Y25 HydrophobicContact CB-CE2 3.98Å; L23-Y25 PolarHBondContact O-N 3.48Å; L23-A41 HydrophobicContact CB-CB 4.12Å; L23-A41 CarbonylContact O-C 3.49Å; L23-A41 WeakPolarHBondContact O-CB 3.44Å; L23-M42 HydrophobicContact CD2-CE 4.28Å; L23-M42 VanDerWaalsContact O-CB 3.23Å; L23-M42 WeakPolarHBondContact O-CB 3.29Å; L23-M42 PolarHBondContact O-N 3.32Å; L23-D492 PolarHBondContact N-O 3.39Å
24Y96.8Very high90.5Very high47 Ų4753.2 Ų53.218%0.18426%0.264CS..  trans54.458.7174.1-60.6-87.2000113.2R26 M42 L87 D492Y24-R26 VanDerWaalsContact C-N 3.33Å; Y24-R26 WeakPolarHBondContact O-CG 3.5Å; Y24-R26 PolarHBondContact O-N 3.24Å; Y24-M42 HydrophobicContact CD2-CB 4.24Å; Y24-M42 HydrophobicContact CD2-CE 4.21Å; Y24-M42 HydrophobicContact CD2-SD 3.77Å; Y24-M42 HydrophobicContact CE2-CE 4.37Å; Y24-M42 HydrophobicContact CE2-SD 4.07Å; Y24-L87 HydrophobicContact CD1-CD1 4.12Å; Y24-L87 HydrophobicContact CD2-CD1 3.97Å; Y24-L87 HydrophobicContact CE1-CD1 3.79Å; Y24-L87 HydrophobicContact CE2-CD1 3.61Å; Y24-L87 HydrophobicContact CG-CD1 4.21Å; Y24-D492 WeakPolarHBondContact CA-O 3.39Å; Y24-D492 HydrophobicContact CD1-CB 3.9Å; Y24-D492 WeakPolarHBondContact CD1-OD2 2.99Å; Y24-D492 HydrophobicContact CE1-CB 4.34Å; Y24-D492 HydrophobicContact CG-CB 4.48Å; Y24-D492 PolarHBondContact N-O 3.28Å
25Y97.5Very high91.4Very high0 Ų052.8 Ų52.80%026%0.262CS..  trans-69.984.9178.7-54.5-93.8000110.8F18 K20 G21 L23 V39 A41 Y46 S490 Q491 I493 V495F18-Y25 HydrophobicContact CD1-CE1 4.27Å; F18-Y25 AromaticContact CE1-CE1 3.89Å; F18-Y25 HydrophobicContact CE1-CE1 3.89Å; K20-Y25 PolarHBondContact N-OH 3.21Å; G21-Y25 WeakPolarHBondContact O-CE2 3.4Å; L23-Y25 HydrophobicContact CB-CE2 3.98Å; L23-Y25 PolarHBondContact O-N 3.48Å; Y25-V39 HydrophobicContact CD1-CG1 3.68Å; Y25-V39 HydrophobicContact CG-CG1 4.41Å; Y25-A41 HydrophobicContact CD1-CB 3.8Å; Y25-A41 HydrophobicContact CE1-CB 3.99Å; Y25-A41 HydrophobicContact CG-CB 4.4Å; Y25-Y46 HydrophobicContact CE1-CD2 4.15Å; Y25-Y46 AromaticContact CE1-CE2 3.83Å; Y25-Y46 HydrophobicContact CE1-CE2 3.83Å; Y25-S490 WeakPolarHBondContact O-CB 3.29Å; Y25-S490 PolarHBondContact O-OG 2.71Å; Y25-Q491 WeakPolarHBondContact CB-O 3.37Å; Y25-I493 WeakPolarHBondContact CE2-O 3.36Å; Y25-V495 HydrophobicContact CD1-CG2 4.34Å; Y25-V495 HydrophobicContact CG-CG2 4.39Å
26R95.1Very high91.9Very high31 Ų3150 Ų5012%0.11725%0.249CC..  trans-107.2-12.6-165.7-74.2177.9174.5-170.20.7115.1Y24 G40 P141 D142 Q460 D492Y24-R26 VanDerWaalsContact C-N 3.33Å; Y24-R26 WeakPolarHBondContact O-CG 3.5Å; Y24-R26 PolarHBondContact O-N 3.24Å; R26-G40 PolarHBondContact N-O 2.84Å; R26-P141 PolarHBondContact NH1-O 3.48Å; R26-D142 IonicContact CZ-OD1 3.61Å; R26-D142 IonicContact NH1-OD1 3.91Å; R26-D142 PolarHBondContact NH1-OD1 3.16Å; R26-D142 IonicContact NH2-OD1 3.77Å; R26-D142 PolarHBondContact NH2-OD1 2.99Å; R26-Q460 HydrophobicContact CB-CB 4.49Å; R26-Q460 HydrophobicContact CG-CB 4.22Å; R26-Q460 HydrophobicContact CG-CG 3.98Å; R26-D492 IonicContact CZ-OD1 3.69Å; R26-D492 IonicContact NE-OD1 3.59Å; R26-D492 PolarHBondContact NE-OD1 3.41Å; R26-D492 IonicContact NH2-OD1 2.73Å; R26-D492 IonicContact NH2-OD2 3.25Å
27V95.9Very high92.2Very high23 Ų2348.1 Ų48.114%0.13924%0.242CC..EExtended strand (participates in β ladder)trans-132.9130.6-178.1-169.40000109.8G40 V93 I96V27-G40 PolarHBondContact O-N 3.32Å; V27-V93 WeakPolarHBondContact CG2-O 3.42Å; V27-I96 HydrophobicContact CB-CD1 4.16Å; V27-I96 HydrophobicContact CG1-CD1 3.85Å; V27-I96 HydrophobicContact CG1-CG1 4.11Å
28L96.9Very high92.4Very high14 Ų1445 Ų457%0.07323%0.229CC..EExtended strand (participates in β ladder)trans-117.6139.5172.7-60.8179.8000108.4L37 Y38 V39 A461 E463 V495L28-L37 HydrophobicContact CB-CD1 4.23Å; L28-L37 HydrophobicContact CD2-CD1 4.27Å; L28-L37 HydrophobicContact CD2-CD2 4.48Å; L28-L37 HydrophobicContact CD2-CG 4.49Å; L28-Y38 WeakPolarHBondContact CA-O 3.36Å; L28-V39 HydrophobicContact CD2-CB 4.17Å; L28-V39 HydrophobicContact CD2-CG1 3.85Å; L28-V39 HydrophobicContact CD2-CG2 3.68Å; L28-A461 HydrophobicContact CB-CB 4.27Å; L28-A461 HydrophobicContact CD1-CB 3.99Å; L28-A461 HydrophobicContact CG-CB 3.87Å; L28-E463 HydrophobicContact CB-CG 3.68Å; L28-E463 HydrophobicContact CD1-CB 4.41Å; L28-E463 HydrophobicContact CD1-CG 4.28Å; L28-V495 HydrophobicContact CD2-CG1 4.45Å; L28-V495 HydrophobicContact CD2-CG2 4.17Å
29L95.6Very high92.5Very high34 Ų3444.8 Ų44.818%0.17823%0.228CC..EExtended strand (participates in β ladder)trans-128.8120.1163173.571.5000107.6Y38 I96 R98 L104L29-Y38 HydrophobicContact CB-CD2 4.44Å; L29-Y38 HydrophobicContact CD2-CD2 4.13Å; L29-Y38 HydrophobicContact CG-CD2 4.3Å; L29-Y38 PolarHBondContact N-O 2.96Å; L29-Y38 PolarHBondContact O-N 2.94Å; L29-I96 HydrophobicContact CB-CB 4Å; L29-I96 HydrophobicContact CB-CG2 3.88Å; L29-I96 HydrophobicContact CD2-CB 4.26Å; L29-I96 HydrophobicContact CD2-CG2 3.52Å; L29-I96 HydrophobicContact CG-CG2 4.35Å; L29-R98 HydrophobicContact CD2-CB 4.28Å; L29-L104 HydrophobicContact CD2-CD2 3.98Å
30L92Very high92.6Very high30 Ų3042.8 Ų42.816%0.15721%0.213CC..EExtended strand (participates in β ladder)trans-96.6119.2178.1-175.169.2000109.9L37 V50 E463 L464 L465 Y488L30-L37 HydrophobicContact CB-CD1 4.43Å; L30-L37 HydrophobicContact CD1-CB 4.47Å; L30-L37 HydrophobicContact CD1-CD1 4.02Å; L30-V50 HydrophobicContact CD1-CG1 4.14Å; L30-E463 HydrophobicContact CB-CB 4.26Å; L30-E463 HydrophobicContact CB-CG 4.35Å; L30-E463 HydrophobicContact CD2-CB 4.38Å; L30-L464 VanDerWaalsContact CD2-C 3.42Å; L30-L464 WeakPolarHBondContact CD2-O 3.34Å; L30-L465 HydrophobicContact CD1-CB 3.91Å; L30-L465 HydrophobicContact CD1-CD1 4.36Å; L30-L465 HydrophobicContact CD1-CD2 3.77Å; L30-L465 HydrophobicContact CD1-CG 4.17Å; L30-L465 HydrophobicContact CD2-CB 3.43Å; L30-L465 VanDerWaalsContact CD2-CB 3.43Å; L30-L465 HydrophobicContact CD2-CD1 3.77Å; L30-L465 HydrophobicContact CD2-CG 4.03Å; L30-L465 HydrophobicContact CG-CB 4.11Å; L30-L465 HydrophobicContact CG-CD1 4.03Å; L30-L465 HydrophobicContact CG-CD2 4.34Å; L30-L465 HydrophobicContact CG-CG 4.33Å; L30-Y488 HydrophobicContact CD1-CD2 4.34Å; L30-Y488 HydrophobicContact CD1-CE2 4.2Å
31D88.6Confident92.8Very high8 Ų837.9 Ų37.94%0.04319%0.192CC..EExtended strand (participates in β ladder)trans-105.8105.9173.9-172.9-23.5000109.7E33 A34 K35 A36 Y38 R98D31-E33 VanDerWaalsContact C-N 3.34Å; D31-E33 WeakPolarHBondContact OD1-CB 3.15Å; D31-E33 PolarHBondContact OD1-N 2.89Å; D31-A34 HydrophobicContact CB-CB 4Å; D31-A34 VanDerWaalsContact CG-CB 3.45Å; D31-A34 PolarHBondContact OD1-N 3.36Å; D31-A34 WeakPolarHBondContact OD2-CB 3.41Å; D31-K35 WeakPolarHBondContact O-CA 3.49Å; D31-K35 PolarHBondContact O-N 3.22Å; D31-A36 PolarHBondContact N-O 3.36Å; D31-A36 PolarHBondContact O-N 3.14Å; D31-Y38 HydrophobicContact CB-CD2 4.44Å; D31-Y38 HydrophobicContact CB-CE2 3.73Å; D31-R98 IonicContact OD1-CZ 3.6Å; D31-R98 IonicContact OD1-NE 2.74Å; D31-R98 IonicContact OD1-NH2 2.96Å; D31-R98 WeakPolarHBondContact OD2-CD 3.4Å; D31-R98 IonicContact OD2-CZ 2.82Å; D31-R98 IonicContact OD2-NE 3.9Å; D31-R98 PolarHBondContact OD2-NE 2.73Å; D31-R98 IonicContact OD2-NH2 3.32Å
32Q82.8Confident93Very high131 Ų13137.3 Ų37.361%0.61218%0.181SC*.THydrogen-bonded Turntrans-67.8-33.1-179.9-178.3168.89.100112.5L465Q32-L465 HydrophobicContact CB-CD1 3.79Å; Q32-L465 HydrophobicContact CG-CD1 3.83Å
33E81.6Confident93.2Very high151 Ų15133.2 Ų33.271%0.70616%0.164SC*.THydrogen-bonded Turntrans-74.4-46.3-179.8-66.9178.4179.200110.5D31 K35 R98D31-E33 VanDerWaalsContact C-N 3.34Å; D31-E33 WeakPolarHBondContact OD1-CB 3.15Å; D31-E33 PolarHBondContact OD1-N 2.89Å; E33-K35 PolarHBondContact O-N 3.33Å; E33-R98 IonicContact OE2-CZ 3.53Å; E33-R98 VanDerWaalsContact OE2-CZ 3.22Å; E33-R98 IonicContact OE2-NH1 3.43Å; E33-R98 PolarHBondContact OE2-NH1 2.79Å; E33-R98 IonicContact OE2-NH2 2.71Å; E33-R98 PolarHBondContact OE2-NH2 2.79Å
34A82.7Confident93.2Very high41 Ų4132.1 Ų32.134%0.33916%0.159SC..THydrogen-bonded Turntrans-77-8.2177.500000113.4D31 A36D31-A34 HydrophobicContact CB-CB 4Å; D31-A34 VanDerWaalsContact CG-CB 3.45Å; D31-A34 PolarHBondContact OD1-N 3.36Å; D31-A34 WeakPolarHBondContact OD2-CB 3.41Å; A34-A36 HydrophobicContact CB-CB 4.07Å; A34-A36 PolarHBondContact O-N 3.24Å
35K82.9Confident93.3Very high108 Ų10829.9 Ų29.947%0.4715%0.15SC..THydrogen-bonded Turntrans47.546.5-170.9-62.7-176.8178.9-177.20111.5D31 E33 V50D31-K35 WeakPolarHBondContact O-CA 3.49Å; D31-K35 PolarHBondContact O-N 3.22Å; E33-K35 PolarHBondContact O-N 3.33Å; K35-V50 HydrophobicContact CB-CG2 3.91Å; K35-V50 WeakPolarHBondContact O-CG1 3.44Å; K35-V50 VanDerWaalsContact O-CG2 3.23Å; K35-V50 WeakPolarHBondContact O-CG2 3.43Å
36A89.9Confident93.2Very high1 Ų130 Ų301%0.00815%0.15CC..EExtended strand (participates in β ladder)trans-127.1141-173.400000110.6D31 A34 Y38 K47D31-A36 PolarHBondContact N-O 3.36Å; D31-A36 PolarHBondContact O-N 3.14Å; A34-A36 HydrophobicContact CB-CB 4.07Å; A34-A36 PolarHBondContact O-N 3.24Å; A36-Y38 HydrophobicContact CB-CE1 4.37Å; A36-Y38 HydrophobicContact CB-CE2 4.03Å; A36-K47 HydrophobicContact CB-CD 4.3Å; A36-K47 HydrophobicContact CB-CG 4.01Å
37L95.3Very high93.3Very high0 Ų029.3 Ų29.30%015%0.148CC..EExtended strand (participates in β ladder)trans-108.1109.4168.1178.369.6000108.3L28 L30 V39 L48 V50 V53 Y488 V495L28-L37 HydrophobicContact CB-CD1 4.23Å; L28-L37 HydrophobicContact CD2-CD1 4.27Å; L28-L37 HydrophobicContact CD2-CD2 4.48Å; L28-L37 HydrophobicContact CD2-CG 4.49Å; L30-L37 HydrophobicContact CB-CD1 4.43Å; L30-L37 HydrophobicContact CD1-CB 4.47Å; L30-L37 HydrophobicContact CD1-CD1 4.02Å; L37-V39 HydrophobicContact CD2-CG2 4.13Å; L37-V39 HydrophobicContact CG-CG2 3.93Å; L37-L48 HydrophobicContact CB-CB 4.36Å; L37-L48 HydrophobicContact CD2-CD1 4.45Å; L37-L48 PolarHBondContact N-O 2.68Å; L37-L48 VanDerWaalsContact N-O 3.13Å; L37-L48 PolarHBondContact O-N 3.29Å; L37-V50 HydrophobicContact CB-CG1 4.04Å; L37-V53 HydrophobicContact CD2-CG1 4.46Å; L37-Y488 HydrophobicContact CD1-CG 4.48Å; L37-Y488 HydrophobicContact CD2-CD1 3.57Å; L37-Y488 HydrophobicContact CD2-CE1 4.22Å; L37-Y488 HydrophobicContact CD2-CG 3.86Å; L37-V495 HydrophobicContact CD2-CG1 4.07Å
38Y97.4Very high93.2Very high0 Ų028.2 Ų28.20%014%0.141CC..EExtended strand (participates in β ladder)trans-85.6132.8173.4-56.1-76.4000109.8L28 L29 D31 A36 F45 Y46 K47 L104 G121 M124L28-Y38 WeakPolarHBondContact CA-O 3.36Å; L29-Y38 HydrophobicContact CB-CD2 4.44Å; L29-Y38 HydrophobicContact CD2-CD2 4.13Å; L29-Y38 HydrophobicContact CG-CD2 4.3Å; L29-Y38 PolarHBondContact N-O 2.96Å; L29-Y38 PolarHBondContact O-N 2.94Å; D31-Y38 HydrophobicContact CB-CD2 4.44Å; D31-Y38 HydrophobicContact CB-CE2 3.73Å; A36-Y38 HydrophobicContact CB-CE1 4.37Å; A36-Y38 HydrophobicContact CB-CE2 4.03Å; Y38-F45 AromaticContact CD1-CZ 3.98Å; Y38-F45 HydrophobicContact CD1-CZ 3.98Å; Y38-F45 HydrophobicContact CG-CZ 4.15Å; Y38-Y46 CarbonylContact C-O 3.59Å; Y38-Y46 VanDerWaalsContact CA-O 3.3Å; Y38-Y46 WeakPolarHBondContact CA-O 3.31Å; Y38-K47 HydrophobicContact CD1-CB 4.08Å; Y38-K47 HydrophobicContact CD1-CG 4.04Å; Y38-K47 HydrophobicContact CE1-CB 4.13Å; Y38-K47 HydrophobicContact CE1-CD 3.86Å; Y38-K47 HydrophobicContact CE1-CG 3.72Å; Y38-L104 HydrophobicContact CD1-CD1 3.6Å; Y38-L104 HydrophobicContact CD2-CD1 4.3Å; Y38-L104 HydrophobicContact CD2-CD2 4.22Å; Y38-L104 HydrophobicContact CE1-CD1 3.47Å; Y38-L104 VanDerWaalsContact CE1-CD1 3.47Å; Y38-L104 HydrophobicContact CE2-CD1 4.19Å; Y38-L104 HydrophobicContact CE2-CD2 3.95Å; Y38-L104 HydrophobicContact CG-CD1 4.03Å; Y38-G121 PolarHBondContact OH-O 3.22Å; Y38-M124 HydrophobicContact CD1-SD 3.68Å; Y38-M124 HydrophobicContact CE1-SD 3.66Å
39V98Very high92.9Very high0 Ų028 Ų280%014%0.14CC..EExtended strand (participates in β ladder)trans-128.3116.6-174.4-172.80000110.1Y25 L28 L37 F45 Y46 L48 V495Y25-V39 HydrophobicContact CD1-CG1 3.68Å; Y25-V39 HydrophobicContact CG-CG1 4.41Å; L28-V39 HydrophobicContact CD2-CB 4.17Å; L28-V39 HydrophobicContact CD2-CG1 3.85Å; L28-V39 HydrophobicContact CD2-CG2 3.68Å; L37-V39 HydrophobicContact CD2-CG2 4.13Å; L37-V39 HydrophobicContact CG-CG2 3.93Å; V39-F45 VanDerWaalsContact O-CD2 3.29Å; V39-F45 WeakPolarHBondContact O-CD2 3.41Å; V39-Y46 PolarHBondContact N-O 3.36Å; V39-Y46 PolarHBondContact O-N 3.31Å; V39-L48 HydrophobicContact CG2-CD1 3.62Å; V39-L48 HydrophobicContact CG2-CG 3.93Å; V39-V495 HydrophobicContact CG1-CG2 3.79Å; V39-V495 HydrophobicContact CG2-CG2 4.26Å
40G97.9Very high92.6Very high0 Ų026.4 Ų26.40%013%0.132CC..EExtended strand (participates in β ladder)trans-84.5123172.800000111.3R26 V27 V93R26-G40 PolarHBondContact N-O 2.84Å; V27-G40 PolarHBondContact O-N 3.32Å; G40-V93 VanDerWaalsContact CA-CB 3.46Å
41A97.8Very high92.3Very high1 Ų128 Ų281%0.00814%0.138CC..  trans-129.4178.3176.500000110.5L23 Y25 T44 Y46 V93L23-A41 HydrophobicContact CB-CB 4.12Å; L23-A41 CarbonylContact O-C 3.49Å; L23-A41 WeakPolarHBondContact O-CB 3.44Å; Y25-A41 HydrophobicContact CD1-CB 3.8Å; Y25-A41 HydrophobicContact CE1-CB 3.99Å; Y25-A41 HydrophobicContact CG-CB 4.4Å; A41-T44 CarbonylContact C-O 3.53Å; A41-T44 WeakPolarHBondContact CA-O 3.37Å; A41-T44 WeakPolarHBondContact CB-O 3.27Å; A41-T44 PolarHBondContact N-O 2.79Å; A41-Y46 HydrophobicContact CB-CD2 4.37Å; A41-Y46 HydrophobicContact CB-CE2 4.07Å; A41-V93 PolarHBondContact O-N 3.04Å
42M97.8Very high92.3Very high24 Ų2429.9 Ų29.912%0.11815%0.149CC..BIsolated β-bridgetrans-70.6123.3169.5-173.1176.874.900109.4L23 Y24 T44 Q90 H92L23-M42 HydrophobicContact CD2-CE 4.28Å; L23-M42 VanDerWaalsContact O-CB 3.23Å; L23-M42 WeakPolarHBondContact O-CB 3.29Å; L23-M42 PolarHBondContact O-N 3.32Å; Y24-M42 HydrophobicContact CD2-CB 4.24Å; Y24-M42 HydrophobicContact CD2-CE 4.21Å; Y24-M42 HydrophobicContact CD2-SD 3.77Å; Y24-M42 HydrophobicContact CE2-CE 4.37Å; Y24-M42 HydrophobicContact CE2-SD 4.07Å; M42-T44 PolarHBondContact O-N 2.94Å; M42-Q90 HydrophobicContact CG-CB 3.6Å; M42-Q90 HydrophobicContact CG-CG 4.19Å; M42-Q90 HydrophobicContact SD-CB 3.73Å; M42-Q90 HydrophobicContact SD-CG 3.7Å; M42-H92 VanDerWaalsContact CG-CE1 3.43Å; M42-H92 WeakPolarHBondContact CG-CE1 3.5Å; M42-H92 VanDerWaalsContact SD-CE1 3.55Å
43N97.7Very high92.7Very high18 Ų1823.7 Ų23.710%0.09612%0.12CC..SBendtrans60.75.3179.6-61.2-31.1000115.5M68 K69 P70 Q90 N91N43-M68 CarbonylContact O-C 3.52Å; N43-M68 PolarHBondContact O-N 2.92Å; N43-K69 HydrophobicContact CB-CG 3.82Å; N43-P70 WeakPolarHBondContact OD1-CD 3.44Å; N43-Q90 PolarHBondContact ND2-OE1 3.29Å; N43-N91 WeakPolarHBondContact CA-O 3.4Å; N43-N91 PolarHBondContact N-O 3.26Å; N43-N91 PolarHBondContact OD1-N 3.19Å
44T97.5Very high93.2Very high13 Ų1320.3 Ų20.38%0.0811%0.107CC..EExtended strand (participates in β ladder)trans-150.9142.8-175.5-44.60000111.7A41 M42 Y46 E65 L66A41-T44 CarbonylContact C-O 3.53Å; A41-T44 WeakPolarHBondContact CA-O 3.37Å; A41-T44 WeakPolarHBondContact CB-O 3.27Å; A41-T44 PolarHBondContact N-O 2.79Å; M42-T44 PolarHBondContact O-N 2.94Å; T44-Y46 HydrophobicContact CG2-CD1 4.31Å; T44-Y46 HydrophobicContact CG2-CD2 4.2Å; T44-Y46 HydrophobicContact CG2-CE1 3.72Å; T44-Y46 HydrophobicContact CG2-CE2 3.58Å; T44-Y46 WeakPolarHBondContact CG2-OH 3.29Å; T44-E65 HydrophobicContact CG2-CG 3.69Å; T44-L66 WeakPolarHBondContact CA-O 3.31Å; T44-L66 WeakPolarHBondContact CG2-O 3.32Å
45F97.6Very high93.6Very high0 Ų020.7 Ų20.70%010%0.103CC..EExtended strand (participates in β ladder)trans-120.8126.6173.8-178-132000109.7Y38 V39 L66 M68 V93 I96 L104 V106 L119 M124Y38-F45 AromaticContact CD1-CZ 3.98Å; Y38-F45 HydrophobicContact CD1-CZ 3.98Å; Y38-F45 HydrophobicContact CG-CZ 4.15Å; V39-F45 VanDerWaalsContact O-CD2 3.29Å; V39-F45 WeakPolarHBondContact O-CD2 3.41Å; F45-L66 HydrophobicContact CB-CB 4.43Å; F45-L66 PolarHBondContact N-O 3.34Å; F45-L66 PolarHBondContact O-N 3.42Å; F45-M68 HydrophobicContact CB-CG 4.44Å; F45-M68 HydrophobicContact CB-SD 3.69Å; F45-V93 HydrophobicContact CB-CG2 4.18Å; F45-V93 HydrophobicContact CD2-CG1 4.42Å; F45-V93 HydrophobicContact CD2-CG2 4.43Å; F45-I96 HydrophobicContact CD2-CD1 4.29Å; F45-I96 HydrophobicContact CE2-CD1 3.5Å; F45-I96 HydrophobicContact CE2-CG1 3.92Å; F45-I96 HydrophobicContact CE2-CG2 4.24Å; F45-I96 HydrophobicContact CZ-CD1 4.3Å; F45-I96 HydrophobicContact CZ-CG1 4.4Å; F45-I96 HydrophobicContact CZ-CG2 3.95Å; F45-L104 HydrophobicContact CE1-CD1 4.04Å; F45-L104 HydrophobicContact CZ-CD1 4.04Å; F45-V106 HydrophobicContact CE1-CG2 4.03Å; F45-V106 HydrophobicContact CZ-CG2 4.24Å; F45-L119 HydrophobicContact CD1-CD1 3.48Å; F45-L119 VanDerWaalsContact CD1-CD1 3.48Å; F45-L119 HydrophobicContact CE1-CD1 3.47Å; F45-L119 VanDerWaalsContact CE1-CD1 3.47Å; F45-M124 HydrophobicContact CD1-CE 3.13Å; F45-M124 HydrophobicContact CD1-SD 4.07Å; F45-M124 HydrophobicContact CE1-CE 3.18Å; F45-M124 HydrophobicContact CE1-SD 3.5Å; F45-M124 VanDerWaalsContact CE1-SD 3.5Å; F45-M124 HydrophobicContact CG-CE 3.91Å; F45-M124 HydrophobicContact CZ-CE 3.99Å; F45-M124 HydrophobicContact CZ-SD 4.2Å
46Y97.2Very high93.9Very high1 Ų118.3 Ų18.30%0.00410%0.098CC..EExtended strand (participates in β ladder)trans-113.1146.6-174.2-61.2-83.8000111.9F18 K20 Y25 Y38 V39 A41 T44 F63 Y64 E65F18-Y46 HydrophobicContact CE1-CD1 4.15Å; F18-Y46 HydrophobicContact CE1-CD2 4.15Å; F18-Y46 HydrophobicContact CE1-CE1 4.27Å; F18-Y46 HydrophobicContact CE1-CE2 4.29Å; F18-Y46 HydrophobicContact CE1-CG 4.09Å; F18-Y46 AromaticContact CZ-CD1 3.76Å; F18-Y46 HydrophobicContact CZ-CD1 3.76Å; F18-Y46 AromaticContact CZ-CE1 3.77Å; F18-Y46 HydrophobicContact CZ-CE1 3.77Å; F18-Y46 HydrophobicContact CZ-CG 4.17Å; K20-Y46 HydrophobicContact CG-CE1 4.43Å; Y25-Y46 HydrophobicContact CE1-CD2 4.15Å; Y25-Y46 AromaticContact CE1-CE2 3.83Å; Y25-Y46 HydrophobicContact CE1-CE2 3.83Å; Y38-Y46 CarbonylContact C-O 3.59Å; Y38-Y46 VanDerWaalsContact CA-O 3.3Å; Y38-Y46 WeakPolarHBondContact CA-O 3.31Å; V39-Y46 PolarHBondContact N-O 3.36Å; V39-Y46 PolarHBondContact O-N 3.31Å; A41-Y46 HydrophobicContact CB-CD2 4.37Å; A41-Y46 HydrophobicContact CB-CE2 4.07Å; T44-Y46 HydrophobicContact CG2-CD1 4.31Å; T44-Y46 HydrophobicContact CG2-CD2 4.2Å; T44-Y46 HydrophobicContact CG2-CE1 3.72Å; T44-Y46 HydrophobicContact CG2-CE2 3.58Å; T44-Y46 WeakPolarHBondContact CG2-OH 3.29Å; Y46-F63 HydrophobicContact CD1-CE2 4.28Å; Y46-F63 HydrophobicContact CD1-CZ 4.22Å; Y46-Y64 WeakPolarHBondContact CA-O 3.26Å; Y46-E65 HydrophobicContact CD1-CB 4.03Å; Y46-E65 HydrophobicContact CD1-CG 4.06Å; Y46-E65 HydrophobicContact CE1-CB 3.97Å; Y46-E65 VanDerWaalsContact CE1-CD 3.41Å; Y46-E65 HydrophobicContact CE1-CG 3.53Å; Y46-E65 VanDerWaalsContact CE1-OE1 3.32Å; Y46-E65 WeakPolarHBondContact CE1-OE1 3.47Å; Y46-E65 PolarHBondContact OH-OE1 2.88Å
47K95.8Very high93.8Very high17 Ų1720.4 Ų20.47%0.07411%0.112CC..EExtended strand (participates in β ladder)trans-110.5119158-175.8-176.9176.1-159.60107.2A36 Y38 G61 F63 Y64 T122 M124A36-K47 HydrophobicContact CB-CD 4.3Å; A36-K47 HydrophobicContact CB-CG 4.01Å; Y38-K47 HydrophobicContact CD1-CB 4.08Å; Y38-K47 HydrophobicContact CD1-CG 4.04Å; Y38-K47 HydrophobicContact CE1-CB 4.13Å; Y38-K47 HydrophobicContact CE1-CD 3.86Å; Y38-K47 HydrophobicContact CE1-CG 3.72Å; K47-G61 PolarHBondContact NZ-O 3.28Å; K47-F63 VanDerWaalsContact O-CA 3.28Å; K47-F63 WeakPolarHBondContact O-CA 3.49Å; K47-Y64 HydrophobicContact CB-CD2 4.33Å; K47-Y64 HydrophobicContact CD-CD2 3.79Å; K47-Y64 HydrophobicContact CD-CE2 4.3Å; K47-Y64 PolarHBondContact N-O 3.07Å; K47-Y64 PolarHBondContact O-N 2.83Å; K47-T122 PolarHBondContact NZ-O 2.94Å; K47-M124 HydrophobicContact CB-CE 4.2Å; K47-M124 HydrophobicContact CB-CG 4.08Å; K47-M124 HydrophobicContact CB-SD 4.07Å; K47-M124 HydrophobicContact CD-CG 4.21Å
48L95.1Very high93.1Very high1 Ų124.7 Ų24.71%0.00514%0.142CC..EExtended strand (participates in β ladder)trans-108.1151-179.1-55.5-174.9000111.5F18 L37 V39 V50 K62 F63F18-L48 HydrophobicContact CB-CD1 4.02Å; F18-L48 HydrophobicContact CD1-CD1 3.62Å; F18-L48 HydrophobicContact CD1-CD2 4.01Å; F18-L48 HydrophobicContact CD1-CG 4.46Å; F18-L48 HydrophobicContact CD2-CD2 4Å; F18-L48 HydrophobicContact CE1-CD1 4.2Å; F18-L48 HydrophobicContact CE1-CD2 3.89Å; F18-L48 HydrophobicContact CE2-CD2 3.9Å; F18-L48 HydrophobicContact CG-CD1 3.79Å; F18-L48 HydrophobicContact CG-CD2 4.05Å; F18-L48 HydrophobicContact CZ-CD2 3.84Å; L37-L48 HydrophobicContact CB-CB 4.36Å; L37-L48 HydrophobicContact CD2-CD1 4.45Å; L37-L48 PolarHBondContact N-O 2.68Å; L37-L48 VanDerWaalsContact N-O 3.13Å; L37-L48 PolarHBondContact O-N 3.29Å; V39-L48 HydrophobicContact CG2-CD1 3.62Å; V39-L48 HydrophobicContact CG2-CG 3.93Å; L48-V50 PolarHBondContact O-N 3.25Å; L48-K62 CarbonylContact C-O 3.59Å; L48-F63 HydrophobicContact CD2-CD2 3.82Å; L48-F63 HydrophobicContact CD2-CE2 3.64Å
49N90.5Very high92.1Very high8 Ų828.9 Ų28.94%0.04317%0.171CC..EExtended strand (participates in β ladder)trans-73.1116.2173.7-177.90.2000110.4E51 N52 V53 D55 K62N49-E51 PolarHBondContact O-N 3.34Å; N49-E51 WeakPolarHBondContact OD1-CB 3.23Å; N49-E51 PolarHBondContact OD1-N 2.88Å; N49-N52 CarbonylContact O-C 3.6Å; N49-N52 PolarHBondContact O-N 2.92Å; N49-V53 PolarHBondContact O-N 3.25Å; N49-D55 PolarHBondContact ND2-OD2 2.89Å; N49-K62 HydrophobicContact CB-CB 4.04Å; N49-K62 PolarHBondContact N-O 3.21Å
50V89.6Confident91.2Very high1 Ų132.4 Ų32.41%0.00621%0.208CC..THydrogen-bonded Turntrans-64-28.7177.8-60.70000112.5L30 K35 L37 L48 N52 L465 V467 Y488 Q497L30-V50 HydrophobicContact CD1-CG1 4.14Å; K35-V50 HydrophobicContact CB-CG2 3.91Å; K35-V50 WeakPolarHBondContact O-CG1 3.44Å; K35-V50 VanDerWaalsContact O-CG2 3.23Å; K35-V50 WeakPolarHBondContact O-CG2 3.43Å; L37-V50 HydrophobicContact CB-CG1 4.04Å; L48-V50 PolarHBondContact O-N 3.25Å; V50-N52 VanDerWaalsContact C-N 3.32Å; V50-L465 HydrophobicContact CB-CD2 3.85Å; V50-L465 HydrophobicContact CG1-CD2 3.82Å; V50-L465 HydrophobicContact CG2-CD2 3.98Å; V50-V467 HydrophobicContact CB-CG2 4.49Å; V50-V467 HydrophobicContact CG2-CG2 4.28Å; V50-Y488 WeakPolarHBondContact CA-OH 3.3Å; V50-Y488 WeakPolarHBondContact CB-OH 3.43Å; V50-Y488 PolarHBondContact O-OH 3.09Å; V50-Q497 PolarHBondContact O-NE2 2.81Å
51E85.2Confident90.6Very high63 Ų6333.3 Ų33.329%0.29422%0.217SC..THydrogen-bonded Turntrans-72.5-27.7179.1-62.3174.3159.600112R16 N49 K62 V467R16-E51 PolarHBondContact NH1-O 3.32Å; N49-E51 PolarHBondContact O-N 3.34Å; N49-E51 WeakPolarHBondContact OD1-CB 3.23Å; N49-E51 PolarHBondContact OD1-N 2.88Å; E51-K62 IonicContact OE2-NZ 2.8Å; E51-K62 PolarHBondContact OE2-NZ 3.25Å; E51-V467 HydrophobicContact CG-CG1 4.15Å
52N88.2Confident90.2Very high49 Ų4937.3 Ų37.326%0.26223%0.234SC..  trans-161.5102.4175.7-179.29.5000110.4R16 N49 V50 N54 D55R16-N52 VanDerWaalsContact CD-OD1 3.31Å; R16-N52 WeakPolarHBondContact CD-OD1 3.43Å; R16-N52 PolarHBondContact NE-OD1 2.92Å; N49-N52 CarbonylContact O-C 3.6Å; N49-N52 PolarHBondContact O-N 2.92Å; V50-N52 VanDerWaalsContact C-N 3.32Å; N52-N54 PolarHBondContact O-N 3.18Å; N52-N54 VanDerWaalsContact O-N 3.16Å; N52-N54 WeakPolarHBondContact OD1-CB 3.48Å; N52-N54 PolarHBondContact OD1-N 3.35Å; N52-N54 VanDerWaalsContact OD1-N 3.13Å; N52-D55 HydrophobicContact CB-CB 4.14Å; N52-D55 VanDerWaalsContact O-CB 3.28Å; N52-D55 WeakPolarHBondContact O-CB 3.2Å; N52-D55 PolarHBondContact O-N 3.05Å
53V92Very high90Very high0 Ų036.7 Ų36.70%023%0.231CC..THydrogen-bonded Turntrans-66.2-18.7-178.6-61.90000113.8R16 F18 L37 N49 D55 Y488 Q497R16-V53 HydrophobicContact CB-CG2 3.78Å; F18-V53 HydrophobicContact CB-CB 4.26Å; F18-V53 HydrophobicContact CB-CG2 4.42Å; L37-V53 HydrophobicContact CD2-CG1 4.46Å; N49-V53 PolarHBondContact O-N 3.25Å; V53-D55 PolarHBondContact O-N 2.87Å; V53-Y488 HydrophobicContact CG1-CD1 3.96Å; V53-Y488 HydrophobicContact CG1-CE1 3.72Å; V53-Q497 HydrophobicContact CB-CB 4.49Å; V53-Q497 HydrophobicContact CG1-CB 4.01Å; V53-Q497 HydrophobicContact CG2-CB 3.63Å; V53-Q497 VanDerWaalsContact N-OE1 3.16Å
54N91.4Very high89.9Confident81 Ų8139.4 Ų39.443%0.43324%0.241SC..THydrogen-bonded Turntrans-75.3-16.2174.9-64.117.5000112.4R16 F17 N52 T56R16-N54 WeakPolarHBondContact CB-OD1 3.41Å; F17-N54 VanDerWaalsContact C-OD1 3.3Å; F17-N54 PolarHBondContact N-OD1 3.35Å; F17-N54 PolarHBondContact O-OD1 2.72Å; N52-N54 PolarHBondContact O-N 3.18Å; N52-N54 VanDerWaalsContact O-N 3.16Å; N52-N54 WeakPolarHBondContact OD1-CB 3.48Å; N52-N54 PolarHBondContact OD1-N 3.35Å; N52-N54 VanDerWaalsContact OD1-N 3.13Å; N54-T56 PolarHBondContact O-N 2.97Å; N54-T56 VanDerWaalsContact O-N 3.09Å
55D89.8Confident89.8Confident48 Ų4843.4 Ų43.426%0.25726%0.258SS..  trans-7796.9-179.7-176.58.6000110.1N49 N52 V53 S57N49-D55 PolarHBondContact ND2-OD2 2.89Å; N52-D55 HydrophobicContact CB-CB 4.14Å; N52-D55 VanDerWaalsContact O-CB 3.28Å; N52-D55 WeakPolarHBondContact O-CB 3.2Å; N52-D55 PolarHBondContact O-N 3.05Å; V53-D55 PolarHBondContact O-N 2.87Å; D55-S57 VanDerWaalsContact C-N 3.31Å; D55-S57 VanDerWaalsContact OD1-CB 3.22Å; D55-S57 WeakPolarHBondContact OD1-CB 3.46Å; D55-S57 PolarHBondContact OD1-N 2.84Å; D55-S57 PolarHBondContact OD1-OG 3.1Å
56T90Very high89.7Confident59 Ų5945.1 Ų45.136%0.36227%0.267SS..  trans-95.919.6175.2680000112.2F18 N54 S58 F63F18-T56 HydrophobicContact CD2-CG2 3.98Å; F18-T56 HydrophobicContact CE2-CG2 3.7Å; N54-T56 PolarHBondContact O-N 2.97Å; N54-T56 VanDerWaalsContact O-N 3.09Å; T56-S58 PolarHBondContact O-N 2.84Å; T56-F63 HydrophobicContact CG2-CD2 4.36Å; T56-F63 HydrophobicContact CG2-CE2 3.99Å; T56-F63 HydrophobicContact CG2-CZ 4.27Å; T56-F63 WeakPolarHBondContact O-CD1 3.01Å
57S87.5Confident89.7Confident44 Ų4451 Ų5131%0.30830%0.295SS..  trans-74.3122.8175.868.80000110.1D55 S59 F63D55-S57 VanDerWaalsContact C-N 3.31Å; D55-S57 VanDerWaalsContact OD1-CB 3.22Å; D55-S57 WeakPolarHBondContact OD1-CB 3.46Å; D55-S57 PolarHBondContact OD1-N 2.84Å; D55-S57 PolarHBondContact OD1-OG 3.1Å; S57-S59 WeakPolarHBondContact CB-OG 3.44Å; S57-S59 PolarHBondContact O-N 2.96Å; S57-S59 VanDerWaalsContact O-N 3.11Å; S57-S59 PolarHBondContact OG-OG 3.32Å; S57-S59 VanDerWaalsContact OG-OG 3.12Å; S57-F63 WeakPolarHBondContact O-CB 3.42Å
58S81.2Confident89.6Confident91 Ų9151 Ų5164%0.63630%0.295SS*.  trans-67.2-7.6174.6-51.10000113T56 G60 G61T56-S58 PolarHBondContact O-N 2.84Å; S58-G60 PolarHBondContact O-N 2.86Å; S58-G61 PolarHBondContact O-N 2.59Å
59S75.9Confident89.7Confident87 Ų8756.7 Ų56.761%0.60832%0.32SS*.THydrogen-bonded Turntrans-63.3125.8178.348.20000111.6S57S57-S59 WeakPolarHBondContact CB-OG 3.44Å; S57-S59 PolarHBondContact O-N 2.96Å; S57-S59 VanDerWaalsContact O-N 3.11Å; S57-S59 PolarHBondContact OG-OG 3.32Å; S57-S59 VanDerWaalsContact OG-OG 3.12Å
60G80.3Confident89.9Confident75 Ų7556.9 Ų56.977%0.77332%0.322SS*.THydrogen-bonded Turntrans82.711.6176.200000115.6S58 K62S58-G60 PolarHBondContact O-N 2.86Å; G60-K62 PolarHBondContact O-N 2.99Å
61G85.5Confident90Very high19 Ų1959 Ų5920%0.19634%0.343CS..SBendtrans67.122.3173.600000114.4K47 S58 Y64K47-G61 PolarHBondContact NZ-O 3.28Å; S58-G61 PolarHBondContact O-N 2.59Å; G61-Y64 VanDerWaalsContact O-CE2 3.29Å; G61-Y64 WeakPolarHBondContact O-CE2 3.31Å
62K88.6Confident90.4Very high84 Ų8461.3 Ų61.337%0.36536%0.362SS..SBendtrans-89.1-23.4177.7-63.8-170.3177.6-176.60113.1L48 N49 E51 G60L48-K62 CarbonylContact C-O 3.59Å; N49-K62 HydrophobicContact CB-CB 4.04Å; N49-K62 PolarHBondContact N-O 3.21Å; E51-K62 IonicContact OE2-NZ 2.8Å; E51-K62 PolarHBondContact OE2-NZ 3.25Å; G60-K62 PolarHBondContact O-N 2.99Å
63F93.8Very high90.6Very high11 Ų1164.8 Ų64.85%0.04838%0.381CS..  trans-124.2128.7177.4179.7-97.1000111.4F18 Y46 K47 L48 T56 S57 E65F18-F63 AromaticContact CE2-CE2 3.84Å; F18-F63 HydrophobicContact CE2-CE2 3.84Å; F18-F63 HydrophobicContact CE2-CZ 4.39Å; F18-F63 HydrophobicContact CZ-CE2 4.11Å; Y46-F63 HydrophobicContact CD1-CE2 4.28Å; Y46-F63 HydrophobicContact CD1-CZ 4.22Å; K47-F63 VanDerWaalsContact O-CA 3.28Å; K47-F63 WeakPolarHBondContact O-CA 3.49Å; L48-F63 HydrophobicContact CD2-CD2 3.82Å; L48-F63 HydrophobicContact CD2-CE2 3.64Å; T56-F63 HydrophobicContact CG2-CD2 4.36Å; T56-F63 HydrophobicContact CG2-CE2 3.99Å; T56-F63 HydrophobicContact CG2-CZ 4.27Å; T56-F63 WeakPolarHBondContact O-CD1 3.01Å; S57-F63 WeakPolarHBondContact O-CB 3.42Å; F63-E65 HydrophobicContact CE1-CB 4.14Å; F63-E65 HydrophobicContact CZ-CB 4.15Å
64Y95.4Very high90.6Very high76 Ų7665.6 Ų65.630%0.29839%0.388SS..EExtended strand (participates in β ladder)trans-137.4146.3170.1-69.1-98.6000110.4Y46 K47 G61 N123 M124Y46-Y64 WeakPolarHBondContact CA-O 3.26Å; K47-Y64 HydrophobicContact CB-CD2 4.33Å; K47-Y64 HydrophobicContact CD-CD2 3.79Å; K47-Y64 HydrophobicContact CD-CE2 4.3Å; K47-Y64 PolarHBondContact N-O 3.07Å; K47-Y64 PolarHBondContact O-N 2.83Å; G61-Y64 VanDerWaalsContact O-CE2 3.29Å; G61-Y64 WeakPolarHBondContact O-CE2 3.31Å; Y64-N123 WeakPolarHBondContact CD1-O 3.36Å; Y64-N123 VanDerWaalsContact CE1-O 3.24Å; Y64-N123 WeakPolarHBondContact CE1-O 3.43Å; Y64-M124 HydrophobicContact CD1-CB 4.47Å; Y64-M124 HydrophobicContact CD2-CG 4.42Å; Y64-M124 HydrophobicContact CG-CB 4.34Å; Y64-M124 HydrophobicContact CG-CG 4.15Å
65E95.4Very high90.8Very high97 Ų9764.4 Ų64.445%0.45338%0.381SS..EExtended strand (participates in β ladder)trans-129.2114176.3175.3162.7-156.400108.1T44 Y46 F63T44-E65 HydrophobicContact CG2-CG 3.69Å; Y46-E65 HydrophobicContact CD1-CB 4.03Å; Y46-E65 HydrophobicContact CD1-CG 4.06Å; Y46-E65 HydrophobicContact CE1-CB 3.97Å; Y46-E65 VanDerWaalsContact CE1-CD 3.41Å; Y46-E65 HydrophobicContact CE1-CG 3.53Å; Y46-E65 VanDerWaalsContact CE1-OE1 3.32Å; Y46-E65 WeakPolarHBondContact CE1-OE1 3.47Å; Y46-E65 PolarHBondContact OH-OE1 2.88Å; F63-E65 HydrophobicContact CE1-CB 4.14Å; F63-E65 HydrophobicContact CZ-CB 4.15Å
66L96.3Very high90.9Very high36 Ų3665.3 Ų65.319%0.18840%0.395CS..EExtended strand (participates in β ladder)trans-110.2111.8178.4178.664.1000109.2T44 F45 M68 L119 I126T44-L66 WeakPolarHBondContact CA-O 3.31Å; T44-L66 WeakPolarHBondContact CG2-O 3.32Å; F45-L66 HydrophobicContact CB-CB 4.43Å; F45-L66 PolarHBondContact N-O 3.34Å; F45-L66 PolarHBondContact O-N 3.42Å; L66-M68 HydrophobicContact CD2-CG 4.33Å; L66-M68 HydrophobicContact CD2-SD 4.42Å; L66-M68 HydrophobicContact CG-CG 4.12Å; L66-L119 HydrophobicContact CD2-CD1 3.86Å; L66-L119 HydrophobicContact CD2-CD2 4.12Å; L66-I126 HydrophobicContact CD1-CD1 4.42Å; L66-I126 HydrophobicContact CD2-CG1 4.27Å
67E96.1Very high91.1Very high123 Ų12367.6 Ų67.658%0.57540%0.402SS*.EExtended strand (participates in β ladder)trans-71.2130173.4-172.9172.1123.100110.4K69E67-K69 VanDerWaalsContact CD-CE 3.49Å; E67-K69 HydrophobicContact CG-CD 4.31Å; E67-K69 HydrophobicContact CG-CG 3.95Å; E67-K69 VanDerWaalsContact OE1-CD 3.22Å; E67-K69 WeakPolarHBondContact OE1-CD 3.46Å; E67-K69 VanDerWaalsContact OE1-CE 3.3Å; E67-K69 WeakPolarHBondContact OE1-CE 3.25Å; E67-K69 IonicContact OE1-NZ 2.71Å; E67-K69 PolarHBondContact OE1-NZ 3.03Å; E67-K69 IonicContact OE2-NZ 3.97Å; E67-K69 PolarHBondContact OE2-NZ 3.44Å
68M94.8Very high91.5Very high18 Ų1865.5 Ų65.59%0.08939%0.387CS..  trans-130.348.5-178.3-59.1-172.179.700110.4N43 F45 L66 N91 V93 T108N43-M68 CarbonylContact O-C 3.52Å; N43-M68 PolarHBondContact O-N 2.92Å; F45-M68 HydrophobicContact CB-CG 4.44Å; F45-M68 HydrophobicContact CB-SD 3.69Å; L66-M68 HydrophobicContact CD2-CG 4.33Å; L66-M68 HydrophobicContact CD2-SD 4.42Å; L66-M68 HydrophobicContact CG-CG 4.12Å; M68-N91 WeakPolarHBondContact O-CB 3.32Å; M68-N91 PolarHBondContact O-ND2 3.11Å; M68-V93 HydrophobicContact SD-CG2 4.11Å; M68-T108 HydrophobicContact CE-CG2 3.67Å; M68-T108 HydrophobicContact SD-CG2 4.22Å
69K95.3Very high92Very high120 Ų12063.4 Ų63.452%0.52237%0.372SS..PPolyproline II helixtrans-68146.5176.6-72.2-179.4-168.7135.70111.5N43 E67N43-K69 HydrophobicContact CB-CG 3.82Å; E67-K69 VanDerWaalsContact CD-CE 3.49Å; E67-K69 HydrophobicContact CG-CD 4.31Å; E67-K69 HydrophobicContact CG-CG 3.95Å; E67-K69 VanDerWaalsContact OE1-CD 3.22Å; E67-K69 WeakPolarHBondContact OE1-CD 3.46Å; E67-K69 VanDerWaalsContact OE1-CE 3.3Å; E67-K69 WeakPolarHBondContact OE1-CE 3.25Å; E67-K69 IonicContact OE1-NZ 2.71Å; E67-K69 PolarHBondContact OE1-NZ 3.03Å; E67-K69 IonicContact OE2-NZ 3.97Å; E67-K69 PolarHBondContact OE2-NZ 3.44Å
70P94.7Very high92.8Very high12 Ų1263.7 Ų63.78%0.07838%0.38CS..PPolyproline II helixtrans-64.2149.3170.9-0.39.9000111.2N43 A74 L75 C89 N91 N110 A111N43-P70 WeakPolarHBondContact OD1-CD 3.44Å; P70-A74 HydrophobicContact CB-CB 4.42Å; P70-L75 HydrophobicContact CB-CD2 4.29Å; P70-L75 HydrophobicContact CB-CG 4.14Å; P70-L75 HydrophobicContact CG-CD2 4.02Å; P70-L75 HydrophobicContact CG-CG 4.35Å; P70-C89 WeakPolarHBondContact CG-O 3.03Å; P70-N91 HydrophobicContact CG-CB 3.83Å; P70-N110 WeakPolarHBondContact CA-OD1 3.3Å; P70-A111 HydrophobicContact CB-CB 3.97Å; P70-A111 HydrophobicContact CG-CB 4.26Å
71G92.8Very high93.3Very high45 Ų4565 Ų6546%0.46436%0.361SS..PPolyproline II helixtrans-67.6159.7172.200000112.5D73 A74 L75G71-D73 VanDerWaalsContact C-N 3.28Å; G71-D73 PolarHBondContact O-N 3.46Å; G71-A74 PolarHBondContact O-N 3.03Å; G71-L75 PolarHBondContact O-N 3.28Å
72T93.6Very high93.5Very high113 Ų11365.5 Ų65.569%0.69336%0.361SS*.Hα-helixtrans-57.2-39.3-179.249.70000113.1L75 A76T72-L75 PolarHBondContact O-N 2.8Å; T72-A76 WeakPolarHBondContact O-CB 3.2Å; T72-A76 PolarHBondContact O-N 3.06Å
73D93Very high93.6Very high121 Ų12173.2 Ų73.265%0.64739%0.387SS*.Hα-helixtrans-69-39.6-179.6-62.8-13.1000111.6G71 A76 Q77G71-D73 VanDerWaalsContact C-N 3.28Å; G71-D73 PolarHBondContact O-N 3.46Å; D73-A76 PolarHBondContact O-N 3.32Å; D73-Q77 VanDerWaalsContact O-CG 3.32Å; D73-Q77 WeakPolarHBondContact O-CG 3.48Å; D73-Q77 PolarHBondContact O-N 3.43Å
74A92.3Very high93.5Very high18 Ų1875.6 Ų75.615%0.14940%0.4CS..Hα-helixtrans-65.2-41.7176.400000111P70 G71 Q77 C78 A111P70-A74 HydrophobicContact CB-CB 4.42Å; G71-A74 PolarHBondContact O-N 3.03Å; A74-Q77 PolarHBondContact O-N 3.43Å; A74-C78 WeakPolarHBondContact O-CB 3.44Å; A74-C78 PolarHBondContact O-N 3.42Å; A74-A111 HydrophobicContact CB-CB 4.11Å
75L94.2Very high93.3Very high56 Ų5676.6 Ų76.629%0.29341%0.408SS..Hα-helixtrans-60.7-47.8173.3-73.7170000111.7P70 G71 T72 Q77 C78 S79 C89P70-L75 HydrophobicContact CB-CD2 4.29Å; P70-L75 HydrophobicContact CB-CG 4.14Å; P70-L75 HydrophobicContact CG-CD2 4.02Å; P70-L75 HydrophobicContact CG-CG 4.35Å; G71-L75 PolarHBondContact O-N 3.28Å; T72-L75 PolarHBondContact O-N 2.8Å; L75-Q77 VanDerWaalsContact C-N 3.34Å; L75-Q77 PolarHBondContact O-N 3.4Å; L75-C78 PolarHBondContact O-N 2.92Å; L75-S79 WeakPolarHBondContact O-CB 3.36Å; L75-S79 PolarHBondContact O-N 3.24Å; L75-S79 PolarHBondContact O-OG 3.38Å; L75-S79 VanDerWaalsContact O-OG 3.07Å; L75-C89 HydrophobicContact CD2-CB 4.19Å; L75-C89 VanDerWaalsContact CD2-O 3.25Å; L75-C89 WeakPolarHBondContact CD2-O 3.02Å
76A93.2Very high93.1Very high66 Ų6680.2 Ų80.255%0.54543%0.425SS..Hα-helixtrans-60.2-43.3179.500000112.2T72 D73T72-A76 WeakPolarHBondContact O-CB 3.2Å; T72-A76 PolarHBondContact O-N 3.06Å; D73-A76 PolarHBondContact O-N 3.32Å
77Q92.9Very high93Very high108 Ų10879.4 Ų79.451%0.50542%0.421SS..Hα-helixtrans-66.4-39.6176.2-70.1177.719.700112.5D73 A74 L75 A80D73-Q77 VanDerWaalsContact O-CG 3.32Å; D73-Q77 WeakPolarHBondContact O-CG 3.48Å; D73-Q77 PolarHBondContact O-N 3.43Å; A74-Q77 PolarHBondContact O-N 3.43Å; L75-Q77 VanDerWaalsContact C-N 3.34Å; L75-Q77 PolarHBondContact O-N 3.4Å; Q77-A80 PolarHBondContact O-N 2.88Å
78C95.3Very high93Very high0 Ų076 Ų760%040%0.404CS..Hα-helixtrans-66.6-41.6178.3-179.40000112.3A74 L75 A80 R81 T82 C89 A111A74-C78 WeakPolarHBondContact O-CB 3.44Å; A74-C78 PolarHBondContact O-N 3.42Å; L75-C78 PolarHBondContact O-N 2.92Å; C78-A80 PolarHBondContact O-N 2.93Å; C78-A80 VanDerWaalsContact O-N 3.11Å; C78-R81 WeakPolarHBondContact O-CA 3.42Å; C78-R81 PolarHBondContact O-N 2.88Å; C78-T82 PolarHBondContact O-N 3.43Å; C78-T82 VanDerWaalsContact O-N 3.09Å; C78-C89 VanDerWaalsContact C-SG 3.51Å; C78-C89 HydrophobicContact CB-CB 3.82Å; C78-C89 WeakPolarHBondContact CB-SG 3.31Å; C78-C89 WeakPolarHBondContact SG-CA 3.42Å; C78-C89 WeakPolarHBondContact SG-CB 3.41Å; C78-C89 CovalentContact SG-SG 2.05Å; C78-C89 PolarHBondContact SG-SG 3.07Å; C78-A111 HydrophobicContact CB-CB 3.78Å
79S92.8Very high93Very high47 Ų4775.2 Ų75.233%0.32940%0.4SS..Hα-helixtrans-59.4-23.5177-66.50000113.4L75 Q85L75-S79 WeakPolarHBondContact O-CB 3.36Å; L75-S79 PolarHBondContact O-N 3.24Å; L75-S79 PolarHBondContact O-OG 3.38Å; L75-S79 VanDerWaalsContact O-OG 3.07Å; S79-Q85 PolarHBondContact OG-NE2 3.41Å
80A91.6Very high93.1Very high92 Ų9271.6 Ų71.676%0.7639%0.385SS*.Hα-helixtrans-80.1-21.2172.400000113.6Q77 C78Q77-A80 PolarHBondContact O-N 2.88Å; C78-A80 PolarHBondContact O-N 2.93Å; C78-A80 VanDerWaalsContact O-N 3.11Å
81R90.9Very high93.2Very high103 Ų10371.2 Ų71.239%0.38938%0.383SS..Hα-helixtrans-95.1-30.5-176.1-65.7177.4-174.9163.76.3113.5C78 L112 S113 Y169C78-R81 WeakPolarHBondContact O-CA 3.42Å; C78-R81 PolarHBondContact O-N 2.88Å; R81-L112 HydrophobicContact CB-CD1 4.34Å; R81-S113 PolarHBondContact NH1-OG 3.47Å; R81-Y169 HydrophobicContact CG-CE2 4.38Å
82T90.6Very high93.4Very high30 Ų3069.3 Ų69.318%0.18436%0.361CS..  trans-139.9153.4-175.3-176.40000112.3C78 D84 K88 C89 L112C78-T82 PolarHBondContact O-N 3.43Å; C78-T82 VanDerWaalsContact O-N 3.09Å; T82-D84 PolarHBondContact OG1-N 2.89Å; T82-K88 HydrophobicContact CG2-CB 4.22Å; T82-C89 VanDerWaalsContact CG2-SG 3.55Å; T82-L112 HydrophobicContact CG2-CD1 3.93Å
83R90.8Very high93.6Very high246 Ų24664 Ų6493%0.92833%0.329SS*.SBendtrans-85.1-23.2171.9-63.1-176.9-178.2-178.40.4112.8Q85R83-Q85 PolarHBondContact O-N 3.15Å; R83-Q85 VanDerWaalsContact O-N 3.13Å
84D92.1Very high93.8Very high60 Ų6060.2 Ų60.232%0.32131%0.306SS..  trans-8581.1179.9-176.1-4000110.5T82 L87 K88T82-D84 PolarHBondContact OG1-N 2.89Å; D84-L87 WeakPolarHBondContact OD1-CB 3.5Å; D84-L87 PolarHBondContact OD1-N 3.34Å; D84-L87 VanDerWaalsContact OD1-N 3.1Å; D84-K88 HydrophobicContact CB-CD 4.23Å; D84-K88 HydrophobicContact CB-CG 4.1Å; D84-K88 WeakPolarHBondContact O-CB 3.36Å; D84-K88 PolarHBondContact O-N 3.17Å
85Q90.5Very high94Very high97 Ų9759.9 Ų59.945%0.45330%0.302SS..THydrogen-bonded Turntrans-81.1-27-178.3-64.5177.73.200112.7S79 R83 C89 Q90S79-Q85 PolarHBondContact OG-NE2 3.41Å; R83-Q85 PolarHBondContact O-N 3.15Å; R83-Q85 VanDerWaalsContact O-N 3.13Å; Q85-C89 WeakPolarHBondContact O-CB 3.31Å; Q85-Q90 PolarHBondContact O-NE2 2.99Å; Q85-Q90 VanDerWaalsContact O-NE2 3.1Å
86E91.8Very high94.1Very high173 Ų17357.7 Ų57.781%0.80829%0.29SS*.THydrogen-bonded Turntrans-73.3-31.7-176.2-67.2-170.2168.700112.6Q90E86-Q90 WeakPolarHBondContact O-CG 3.16Å
87L93.9Very high94.3Very high19 Ų1955.7 Ų55.710%0.09927%0.27CS..THydrogen-bonded Turntrans-106.7-56.7177.8-172.365.9000112.1Y24 D84 Q90 H92 P141Y24-L87 HydrophobicContact CD1-CD1 4.12Å; Y24-L87 HydrophobicContact CD2-CD1 3.97Å; Y24-L87 HydrophobicContact CE1-CD1 3.79Å; Y24-L87 HydrophobicContact CE2-CD1 3.61Å; Y24-L87 HydrophobicContact CG-CD1 4.21Å; D84-L87 WeakPolarHBondContact OD1-CB 3.5Å; D84-L87 PolarHBondContact OD1-N 3.34Å; D84-L87 VanDerWaalsContact OD1-N 3.1Å; L87-Q90 PolarHBondContact O-N 3.27Å; L87-H92 PolarHBondContact O-NE2 3.33Å; L87-P141 HydrophobicContact CG-CG 4.03Å
88K95.2Very high94.4Very high53 Ų5354.7 Ų54.723%0.2326%0.262CS..THydrogen-bonded Turntrans-76.8-27.4-168-58.6-168-179.9-157.20114.3T82 D84 Q90 L112 D140T82-K88 HydrophobicContact CG2-CB 4.22Å; D84-K88 HydrophobicContact CB-CD 4.23Å; D84-K88 HydrophobicContact CB-CG 4.1Å; D84-K88 WeakPolarHBondContact O-CB 3.36Å; D84-K88 PolarHBondContact O-N 3.17Å; K88-Q90 VanDerWaalsContact C-N 3.33Å; K88-L112 HydrophobicContact CB-CD2 4.18Å; K88-D140 VanDerWaalsContact CE-OD2 3.23Å; K88-D140 WeakPolarHBondContact CE-OD2 3.1Å; K88-D140 IonicContact NZ-OD2 2.71Å; K88-D140 PolarHBondContact NZ-OD2 3.09Å
89C96.3Very high94.3Very high1 Ų156.1 Ų56.11%0.00727%0.268CS..THydrogen-bonded Turntrans-85.8-4175.5-62.70000113.9P70 L75 C78 T82 Q85 A111P70-C89 WeakPolarHBondContact CG-O 3.03Å; L75-C89 HydrophobicContact CD2-CB 4.19Å; L75-C89 VanDerWaalsContact CD2-O 3.25Å; L75-C89 WeakPolarHBondContact CD2-O 3.02Å; C78-C89 VanDerWaalsContact C-SG 3.51Å; C78-C89 HydrophobicContact CB-CB 3.82Å; C78-C89 WeakPolarHBondContact CB-SG 3.31Å; C78-C89 WeakPolarHBondContact SG-CA 3.42Å; C78-C89 WeakPolarHBondContact SG-CB 3.41Å; C78-C89 CovalentContact SG-SG 2.05Å; C78-C89 PolarHBondContact SG-SG 3.07Å; T82-C89 VanDerWaalsContact CG2-SG 3.55Å; Q85-C89 WeakPolarHBondContact O-CB 3.31Å; C89-A111 VanDerWaalsContact O-CB 3.27Å; C89-A111 WeakPolarHBondContact O-CB 3.26Å
90Q96.3Very high94.3Very high44 Ų4456.5 Ų56.521%0.20628%0.279CS..SBendtrans-80166.1171.7-53.4-55-4800111M42 N43 Q85 E86 L87 K88 T109M42-Q90 HydrophobicContact CG-CB 3.6Å; M42-Q90 HydrophobicContact CG-CG 4.19Å; M42-Q90 HydrophobicContact SD-CB 3.73Å; M42-Q90 HydrophobicContact SD-CG 3.7Å; N43-Q90 PolarHBondContact ND2-OE1 3.29Å; Q85-Q90 PolarHBondContact O-NE2 2.99Å; Q85-Q90 VanDerWaalsContact O-NE2 3.1Å; E86-Q90 WeakPolarHBondContact O-CG 3.16Å; L87-Q90 PolarHBondContact O-N 3.27Å; K88-Q90 VanDerWaalsContact C-N 3.33Å; Q90-T109 PolarHBondContact O-OG1 3.06Å; Q90-T109 VanDerWaalsContact O-OG1 3.14Å
91N97Very high94.3Very high4 Ų457 Ų572%0.02127%0.269CS..  trans-98.4108.2177.9-172.122.1000110.2N43 M68 P70 T108 T109 N110N43-N91 WeakPolarHBondContact CA-O 3.4Å; N43-N91 PolarHBondContact N-O 3.26Å; N43-N91 PolarHBondContact OD1-N 3.19Å; M68-N91 WeakPolarHBondContact O-CB 3.32Å; M68-N91 PolarHBondContact O-ND2 3.11Å; P70-N91 HydrophobicContact CG-CB 3.83Å; N91-T108 PolarHBondContact ND2-OG1 3.07Å; N91-T108 WeakPolarHBondContact OD1-CB 3.46Å; N91-T108 PolarHBondContact OD1-OG1 3.34Å; N91-T109 PolarHBondContact OD1-N 3.43Å; N91-N110 WeakPolarHBondContact OD1-CA 3.26Å; N91-N110 PolarHBondContact OD1-N 3.37Å
92H97.9Very high94.4Very high4 Ų452.9 Ų52.92%0.01926%0.259CS..BIsolated β-bridgetrans-101.8131.4178.7-66.3-103000109.9M42 L87 R94 T108 T109 P141M42-H92 VanDerWaalsContact CG-CE1 3.43Å; M42-H92 WeakPolarHBondContact CG-CE1 3.5Å; M42-H92 VanDerWaalsContact SD-CE1 3.55Å; L87-H92 PolarHBondContact O-NE2 3.33Å; H92-R94 PolarHBondContact O-N 3.28Å; H92-T108 CarbonylContact O-C 3.58Å; H92-T108 WeakPolarHBondContact O-CA 3.21Å; H92-T108 WeakPolarHBondContact O-CB 3.15Å; H92-T109 HydrophobicContact CB-CG2 4Å; H92-T109 PolarHBondContact N-OG1 3.34Å; H92-T109 PolarHBondContact O-N 2.89Å; H92-P141 HydrophobicContact CB-CB 3.99Å
93V97.8Very high94.6Very high3 Ų352.8 Ų52.82%0.01826%0.257CS..EExtended strand (participates in β ladder)trans-70.9120.4168.1179.20000108.8V27 G40 A41 F45 M68 I96 V106 T108V27-V93 WeakPolarHBondContact CG2-O 3.42Å; G40-V93 VanDerWaalsContact CA-CB 3.46Å; A41-V93 PolarHBondContact O-N 3.04Å; F45-V93 HydrophobicContact CB-CG2 4.18Å; F45-V93 HydrophobicContact CD2-CG1 4.42Å; F45-V93 HydrophobicContact CD2-CG2 4.43Å; M68-V93 HydrophobicContact SD-CG2 4.11Å; V93-I96 HydrophobicContact CG1-CD1 4.09Å; V93-I96 HydrophobicContact CG1-CG1 3.68Å; V93-V106 HydrophobicContact CG1-CG1 3.86Å; V93-T108 HydrophobicContact CB-CG2 4.4Å; V93-T108 HydrophobicContact CG2-CG2 3.93Å
94R96.5Very high94.9Very high41 Ų4141 Ų4116%0.15521%0.213CC..EExtended strand (participates in β ladder)trans-114.4-18.3-176.3-65.5-61.8-67.4144.2-6113.8H92 C107 T109 C137 P138 P141 D143H92-R94 PolarHBondContact O-N 3.28Å; R94-C107 PolarHBondContact N-O 3.02Å; R94-T109 HydrophobicContact CG-CG2 3.61Å; R94-C137 HydrophobicContact CB-CB 4.4Å; R94-P138 HydrophobicContact CB-CG 4.25Å; R94-P138 HydrophobicContact CG-CG 4.18Å; R94-P141 VanDerWaalsContact CZ-O 3.32Å; R94-P141 PolarHBondContact NE-O 3.17Å; R94-D143 PolarHBondContact NH2-O 3.38Å
95T96.3Very high95.2Very high11 Ų1138.8 Ų38.87%0.06720%0.2CC..EExtended strand (participates in β ladder)trans-147.5130.5-179-57.80000109.4L97 V106 C107 A147T95-L97 HydrophobicContact CG2-CD1 3.9Å; T95-L97 HydrophobicContact CG2-CD2 4.28Å; T95-L97 HydrophobicContact CG2-CG 3.75Å; T95-V106 WeakPolarHBondContact O-CA 3.43Å; T95-C107 PolarHBondContact N-O 3.37Å; T95-C107 PolarHBondContact O-N 2.81Å; T95-A147 HydrophobicContact CG2-CB 3.9Å
96I97.2Very high95.5Very high9 Ų934.1 Ų34.15%0.04618%0.179CC..EExtended strand (participates in β ladder)trans-131.9118173.2-48.3158.7000105.9V27 L29 F45 V93 F105 V106V27-I96 HydrophobicContact CB-CD1 4.16Å; V27-I96 HydrophobicContact CG1-CD1 3.85Å; V27-I96 HydrophobicContact CG1-CG1 4.11Å; L29-I96 HydrophobicContact CB-CB 4Å; L29-I96 HydrophobicContact CB-CG2 3.88Å; L29-I96 HydrophobicContact CD2-CB 4.26Å; L29-I96 HydrophobicContact CD2-CG2 3.52Å; L29-I96 HydrophobicContact CG-CG2 4.35Å; F45-I96 HydrophobicContact CD2-CD1 4.29Å; F45-I96 HydrophobicContact CE2-CD1 3.5Å; F45-I96 HydrophobicContact CE2-CG1 3.92Å; F45-I96 HydrophobicContact CE2-CG2 4.24Å; F45-I96 HydrophobicContact CZ-CD1 4.3Å; F45-I96 HydrophobicContact CZ-CG1 4.4Å; F45-I96 HydrophobicContact CZ-CG2 3.95Å; V93-I96 HydrophobicContact CG1-CD1 4.09Å; V93-I96 HydrophobicContact CG1-CG1 3.68Å; I96-F105 WeakPolarHBondContact CA-O 3.43Å; I96-V106 HydrophobicContact CG2-CG2 4.35Å
97L96.5Very high95.8Very high25 Ų2525.9 Ų25.913%0.13114%0.14CC..EExtended strand (participates in β ladder)trans-126.6138.1179-55.7168.5000109.3T95 L104 F105 A147 W149 V161T95-L97 HydrophobicContact CG2-CD1 3.9Å; T95-L97 HydrophobicContact CG2-CD2 4.28Å; T95-L97 HydrophobicContact CG2-CG 3.75Å; L97-L104 CarbonylContact O-C 3.55Å; L97-L104 WeakPolarHBondContact O-CA 3.19Å; L97-F105 HydrophobicContact CB-CB 4.25Å; L97-F105 HydrophobicContact CD1-CD1 4.23Å; L97-F105 PolarHBondContact N-O 2.93Å; L97-F105 PolarHBondContact O-N 2.8Å; L97-A147 HydrophobicContact CD1-CB 4.07Å; L97-A147 WeakPolarHBondContact CD2-O 3.31Å; L97-W149 HydrophobicContact CB-CB 4.16Å; L97-W149 HydrophobicContact CD1-CB 4.26Å; L97-V161 HydrophobicContact CD1-CG2 3.73Å
98R94.8Very high96Very high87 Ų8725 Ų2533%0.32814%0.135SC..EExtended strand (participates in β ladder)trans-84.7128.9170.6-167.8-178.8-169.5-113.64.8109.6L29 D31 E33L29-R98 HydrophobicContact CD2-CB 4.28Å; D31-R98 IonicContact OD1-CZ 3.6Å; D31-R98 IonicContact OD1-NE 2.74Å; D31-R98 IonicContact OD1-NH2 2.96Å; D31-R98 WeakPolarHBondContact OD2-CD 3.4Å; D31-R98 IonicContact OD2-CZ 2.82Å; D31-R98 IonicContact OD2-NE 3.9Å; D31-R98 PolarHBondContact OD2-NE 2.73Å; D31-R98 IonicContact OD2-NH2 3.32Å; E33-R98 IonicContact OE2-CZ 3.53Å; E33-R98 VanDerWaalsContact OE2-CZ 3.22Å; E33-R98 IonicContact OE2-NH1 3.43Å; E33-R98 PolarHBondContact OE2-NH1 2.79Å; E33-R98 IonicContact OE2-NH2 2.71Å; E33-R98 PolarHBondContact OE2-NH2 2.79Å
99K94.7Very high96Very high29 Ų2922.5 Ų22.513%0.12612%0.124CC..  trans-86.1165.1173.6-60.7-174.5-174.5176.50111D101 G102 N103 F105 T118 W149K99-D101 WeakPolarHBondContact CB-OD1 3.42Å; K99-D101 PolarHBondContact O-N 2.85Å; K99-G102 PolarHBondContact O-N 2.79Å; K99-N103 WeakPolarHBondContact CB-O 3.46Å; K99-N103 HydrophobicContact CD-CB 4.39Å; K99-N103 PolarHBondContact N-O 2.81Å; K99-F105 HydrophobicContact CG-CB 4.31Å; K99-T118 PolarHBondContact NZ-OG1 2.9Å; K99-W149 HydrophobicContact CB-CZ2 4.28Å; K99-W149 HydrophobicContact CD-CH2 3.86Å; K99-W149 HydrophobicContact CD-CZ2 3.73Å; K99-W149 HydrophobicContact CD-CZ3 4.38Å; K99-W149 HydrophobicContact CG-CD2 3.92Å; K99-W149 HydrophobicContact CG-CE3 4.25Å; K99-W149 HydrophobicContact CG-CG 4.49Å; K99-W149 HydrophobicContact CG-CH2 4.13Å; K99-W149 HydrophobicContact CG-CZ2 3.75Å; K99-W149 HydrophobicContact CG-CZ3 4.36Å
100G91.5Very high96Very high55 Ų5523.6 Ų23.657%0.56713%0.13SC*.THydrogen-bonded Turntrans-62.7-22.1177.200000114.9G102 E151G100-G102 VanDerWaalsContact C-N 3.3Å; G100-E151 WeakPolarHBondContact CA-OE2 3.49Å; G100-E151 PolarHBondContact N-OE2 2.88Å
101D92.3Very high96Very high103 Ų10321.5 Ų21.555%0.55112%0.12SC*.THydrogen-bonded Turntrans-851.5175.364.8-0.8000113.7K99 N103K99-D101 WeakPolarHBondContact CB-OD1 3.42Å; K99-D101 PolarHBondContact O-N 2.85Å; D101-N103 VanDerWaalsContact C-N 3.28Å; D101-N103 PolarHBondContact O-N 2.81Å; D101-N103 VanDerWaalsContact OD1-CB 3.22Å; D101-N103 WeakPolarHBondContact OD1-CB 3.28Å; D101-N103 PolarHBondContact OD1-N 2.86Å; D101-N103 PolarHBondContact OD1-ND2 3.49Å; D101-N103 PolarHBondContact OD2-ND2 2.88Å
102G92.1Very high95.9Very high17 Ų1721.9 Ų21.918%0.17512%0.122CC..SBendtrans83.4-5.1-176.700000114.6K99 G100K99-G102 PolarHBondContact O-N 2.79Å; G100-G102 VanDerWaalsContact C-N 3.3Å
103N95.9Very high95.7Very high27 Ų2723.6 Ų23.614%0.14414%0.135CC..  trans-75.2157.6174.6-65.3-39.8000111.3K99 D101 T118 L119 L127K99-N103 WeakPolarHBondContact CB-O 3.46Å; K99-N103 HydrophobicContact CD-CB 4.39Å; K99-N103 PolarHBondContact N-O 2.81Å; D101-N103 VanDerWaalsContact C-N 3.28Å; D101-N103 PolarHBondContact O-N 2.81Å; D101-N103 VanDerWaalsContact OD1-CB 3.22Å; D101-N103 WeakPolarHBondContact OD1-CB 3.28Å; D101-N103 PolarHBondContact OD1-N 2.86Å; D101-N103 PolarHBondContact OD1-ND2 3.49Å; D101-N103 PolarHBondContact OD2-ND2 2.88Å; N103-T118 HydrophobicContact CB-CG2 4.03Å; N103-L119 CarbonylContact C-O 3.54Å; N103-L119 WeakPolarHBondContact CA-O 3.28Å; N103-L119 WeakPolarHBondContact CB-O 3.47Å; N103-L127 HydrophobicContact CB-CD1 4.41Å; N103-L127 WeakPolarHBondContact OD1-CD1 3.23Å
104L97.2Very high95.7Very high0 Ų023.9 Ų23.90%014%0.137CC..EExtended strand (participates in β ladder)trans-99.1131.3178.5-54.7174.7000110.3L29 Y38 F45 L97 V106 T118 L119 M124L29-L104 HydrophobicContact CD2-CD2 3.98Å; Y38-L104 HydrophobicContact CD1-CD1 3.6Å; Y38-L104 HydrophobicContact CD2-CD1 4.3Å; Y38-L104 HydrophobicContact CD2-CD2 4.22Å; Y38-L104 HydrophobicContact CE1-CD1 3.47Å; Y38-L104 VanDerWaalsContact CE1-CD1 3.47Å; Y38-L104 HydrophobicContact CE2-CD1 4.19Å; Y38-L104 HydrophobicContact CE2-CD2 3.95Å; Y38-L104 HydrophobicContact CG-CD1 4.03Å; F45-L104 HydrophobicContact CE1-CD1 4.04Å; F45-L104 HydrophobicContact CZ-CD1 4.04Å; L97-L104 CarbonylContact O-C 3.55Å; L97-L104 WeakPolarHBondContact O-CA 3.19Å; L104-V106 HydrophobicContact CB-CG2 4.1Å; L104-T118 CarbonylContact O-C 3.57Å; L104-T118 VanDerWaalsContact O-CA 3.23Å; L104-T118 WeakPolarHBondContact O-CA 3.26Å; L104-L119 HydrophobicContact CB-CB 4.31Å; L104-L119 PolarHBondContact N-O 3.4Å; L104-L119 PolarHBondContact O-N 2.8Å; L104-M124 HydrophobicContact CD1-SD 4Å
105F97.3Very high95.7Very high12 Ų1223.7 Ų23.75%0.05314%0.139CC..EExtended strand (participates in β ladder)trans-95.1113.8165.3-175-82.8000108.3I96 L97 K99 C107 V116 I136 W149 V161I96-F105 WeakPolarHBondContact CA-O 3.43Å; L97-F105 HydrophobicContact CB-CB 4.25Å; L97-F105 HydrophobicContact CD1-CD1 4.23Å; L97-F105 PolarHBondContact N-O 2.93Å; L97-F105 PolarHBondContact O-N 2.8Å; K99-F105 HydrophobicContact CG-CB 4.31Å; F105-C107 HydrophobicContact CE1-CB 4.5Å; F105-V116 HydrophobicContact CD1-CG1 4.35Å; F105-V116 HydrophobicContact CD2-CG1 3.91Å; F105-V116 HydrophobicContact CE1-CG1 3.81Å; F105-V116 HydrophobicContact CE1-CG2 4.11Å; F105-V116 HydrophobicContact CE2-CG1 3.33Å; F105-V116 HydrophobicContact CG-CG1 4.39Å; F105-V116 HydrophobicContact CZ-CB 4.19Å; F105-V116 HydrophobicContact CZ-CG1 3.27Å; F105-V116 HydrophobicContact CZ-CG2 3.79Å; F105-I136 HydrophobicContact CE1-CG2 3.99Å; F105-I136 HydrophobicContact CZ-CG2 4.15Å; F105-W149 HydrophobicContact CB-CE3 4.36Å; F105-W149 HydrophobicContact CB-CZ3 4.47Å; F105-W149 HydrophobicContact CD2-CE3 4.13Å; F105-W149 HydrophobicContact CD2-CH2 4.46Å; F105-W149 AromaticContact CD2-CZ3 3.56Å; F105-W149 HydrophobicContact CD2-CZ3 3.56Å; F105-W149 AromaticContact CE2-CZ3 3.97Å; F105-W149 HydrophobicContact CE2-CZ3 3.97Å; F105-W149 HydrophobicContact CG-CE3 4.27Å; F105-W149 HydrophobicContact CG-CZ3 4.16Å; F105-V161 HydrophobicContact CE1-CB 4.35Å; F105-V161 HydrophobicContact CE1-CG1 4.26Å; F105-V161 HydrophobicContact CE1-CG2 4.26Å; F105-V161 HydrophobicContact CE2-CG1 4.31Å; F105-V161 HydrophobicContact CZ-CB 4.19Å; F105-V161 HydrophobicContact CZ-CG1 3.75Å
106V97.9Very high95.7Very high0 Ų023.2 Ų23.20%014%0.136CC..EExtended strand (participates in β ladder)trans-118.1125.9-175.9-175.20000109.3F45 V93 T95 I96 L104 T108 V116 S117 L119F45-V106 HydrophobicContact CE1-CG2 4.03Å; F45-V106 HydrophobicContact CZ-CG2 4.24Å; V93-V106 HydrophobicContact CG1-CG1 3.86Å; T95-V106 WeakPolarHBondContact O-CA 3.43Å; I96-V106 HydrophobicContact CG2-CG2 4.35Å; L104-V106 HydrophobicContact CB-CG2 4.1Å; V106-T108 HydrophobicContact CG1-CG2 3.97Å; V106-V116 CarbonylContact O-C 3.48Å; V106-V116 WeakPolarHBondContact O-CA 3.42Å; V106-S117 PolarHBondContact N-O 3.5Å; V106-S117 PolarHBondContact O-N 3.01Å; V106-L119 HydrophobicContact CG2-CD1 3.81Å; V106-L119 HydrophobicContact CG2-CG 4.22Å
107C97.6Very high95.7Very high0 Ų022.9 Ų22.90%013%0.134CC..EExtended strand (participates in β ladder)trans-117.8134174.7-162.50000110.2R94 T95 F105 I115 V116 C137R94-C107 PolarHBondContact N-O 3.02Å; T95-C107 PolarHBondContact N-O 3.37Å; T95-C107 PolarHBondContact O-N 2.81Å; F105-C107 HydrophobicContact CE1-CB 4.5Å; C107-I115 WeakPolarHBondContact CA-O 3.39Å; C107-V116 HydrophobicContact CB-CG2 4.03Å; C107-V116 VanDerWaalsContact SG-CG2 3.54Å; C107-C137 HydrophobicContact CB-CB 3.55Å; C107-C137 WeakPolarHBondContact CB-SG 3.27Å; C107-C137 WeakPolarHBondContact SG-CB 3.3Å; C107-C137 CovalentContact SG-SG 2.03Å; C107-C137 PolarHBondContact SG-SG 3.12Å
108T97Very high95.7Very high0 Ų022.2 Ų22.20%013%0.131CC..EExtended strand (participates in β ladder)trans-132.7154.2-173.378.50000111.4M68 N91 H92 V93 V106 P114 I115M68-T108 HydrophobicContact CE-CG2 3.67Å; M68-T108 HydrophobicContact SD-CG2 4.22Å; N91-T108 PolarHBondContact ND2-OG1 3.07Å; N91-T108 WeakPolarHBondContact OD1-CB 3.46Å; N91-T108 PolarHBondContact OD1-OG1 3.34Å; H92-T108 CarbonylContact O-C 3.58Å; H92-T108 WeakPolarHBondContact O-CA 3.21Å; H92-T108 WeakPolarHBondContact O-CB 3.15Å; V93-T108 HydrophobicContact CB-CG2 4.4Å; V93-T108 HydrophobicContact CG2-CG2 3.93Å; V106-T108 HydrophobicContact CG1-CG2 3.97Å; T108-P114 CarbonylContact O-C 3.52Å; T108-P114 WeakPolarHBondContact O-CA 3.15Å; T108-P114 WeakPolarHBondContact O-CB 3.46Å; T108-I115 PolarHBondContact N-O 3.45Å; T108-I115 PolarHBondContact O-N 3.14Å; T108-I115 WeakPolarHBondContact OG1-CG1 3.19Å
109T96.3Very high95.8Very high0 Ų018.1 Ų18.10%012%0.116CC..  trans-70.2-32.2-174.959.20000114.2Q90 N91 H92 R94 A111 L112 S113 S139 P141Q90-T109 PolarHBondContact O-OG1 3.06Å; Q90-T109 VanDerWaalsContact O-OG1 3.14Å; N91-T109 PolarHBondContact OD1-N 3.43Å; H92-T109 HydrophobicContact CB-CG2 4Å; H92-T109 PolarHBondContact N-OG1 3.34Å; H92-T109 PolarHBondContact O-N 2.89Å; R94-T109 HydrophobicContact CG-CG2 3.61Å; T109-A111 PolarHBondContact O-N 3.45Å; T109-L112 CarbonylContact O-C 3.56Å; T109-L112 PolarHBondContact O-N 3.17Å; T109-S113 CarbonylContact O-C 3.45Å; T109-S113 VanDerWaalsContact O-C 3.27Å; T109-S113 PolarHBondContact O-N 3.27Å; T109-S139 WeakPolarHBondContact CB-O 3.26Å; T109-P141 HydrophobicContact CG2-CB 4.39Å
110N96Very high95.8Very high24 Ų2418.5 Ų18.513%0.12812%0.119CC..THydrogen-bonded Turntrans39.464.9177.3-174.955.8000114P70 N91 S113 I115P70-N110 WeakPolarHBondContact CA-OD1 3.3Å; N91-N110 WeakPolarHBondContact OD1-CA 3.26Å; N91-N110 PolarHBondContact OD1-N 3.37Å; N110-S113 WeakPolarHBondContact CB-O 3.44Å; N110-S113 PolarHBondContact ND2-O 3.48Å; N110-S113 PolarHBondContact O-N 3.3Å; N110-I115 HydrophobicContact CB-CD1 4.02Å; N110-I115 HydrophobicContact CB-CG1 3.82Å; N110-I115 HydrophobicContact CB-CG2 4.25Å
111A95.7Very high95.9Very high0 Ų016 Ų160%09%0.094CC..THydrogen-bonded Turntrans55.356.7179.400000113.1P70 A74 C78 C89 T109 S113P70-A111 HydrophobicContact CB-CB 3.97Å; P70-A111 HydrophobicContact CG-CB 4.26Å; A74-A111 HydrophobicContact CB-CB 4.11Å; C78-A111 HydrophobicContact CB-CB 3.78Å; C89-A111 VanDerWaalsContact O-CB 3.27Å; C89-A111 WeakPolarHBondContact O-CB 3.26Å; T109-A111 PolarHBondContact O-N 3.45Å; A111-S113 PolarHBondContact O-N 3.22Å; A111-S113 VanDerWaalsContact O-N 3.13Å
112L95.2Very high95.8Very high12 Ų1215.4 Ų15.46%0.0639%0.094CC..THydrogen-bonded Turntrans61.611.1-176.8-56.5177.2000115.4R81 T82 K88 T109 S139R81-L112 HydrophobicContact CB-CD1 4.34Å; T82-L112 HydrophobicContact CG2-CD1 3.93Å; K88-L112 HydrophobicContact CB-CD2 4.18Å; T109-L112 CarbonylContact O-C 3.56Å; T109-L112 PolarHBondContact O-N 3.17Å; L112-S139 WeakPolarHBondContact CD2-O 3.48Å; L112-S139 PolarHBondContact O-OG 3.03Å
113S95Very high95.8Very high40 Ų4016.6 Ų16.628%0.2810%0.096SC..SBendtrans-127.878.9179.8-55.90000110.2R81 T109 N110 A111R81-S113 PolarHBondContact NH1-OG 3.47Å; T109-S113 CarbonylContact O-C 3.45Å; T109-S113 VanDerWaalsContact O-C 3.27Å; T109-S113 PolarHBondContact O-N 3.27Å; N110-S113 WeakPolarHBondContact CB-O 3.44Å; N110-S113 PolarHBondContact ND2-O 3.48Å; N110-S113 PolarHBondContact O-N 3.3Å; A111-S113 PolarHBondContact O-N 3.22Å; A111-S113 VanDerWaalsContact O-N 3.13Å
114P96.5Very high95.6Very high9 Ų915.7 Ų15.76%0.0589%0.091CC..  trans-56142.2-168.6-30.836.6000114.8T108 G133 S139T108-P114 CarbonylContact O-C 3.52Å; T108-P114 WeakPolarHBondContact O-CA 3.15Å; T108-P114 WeakPolarHBondContact O-CB 3.46Å; P114-G133 WeakPolarHBondContact O-CA 3.23Å; P114-G133 PolarHBondContact O-N 2.86Å; P114-S139 WeakPolarHBondContact CD-OG 3.2Å; P114-S139 WeakPolarHBondContact CG-OG 3.34Å
115I96.5Very high95.5Very high38 Ų3821.4 Ų21.420%0.19512%0.118CC..EExtended strand (participates in β ladder)trans-128.6152176.963.6175.6000110.7C107 T108 N110 M131C107-I115 WeakPolarHBondContact CA-O 3.39Å; T108-I115 PolarHBondContact N-O 3.45Å; T108-I115 PolarHBondContact O-N 3.14Å; T108-I115 WeakPolarHBondContact OG1-CG1 3.19Å; N110-I115 HydrophobicContact CB-CD1 4.02Å; N110-I115 HydrophobicContact CB-CG1 3.82Å; N110-I115 HydrophobicContact CB-CG2 4.25Å; I115-M131 CarbonylContact C-O 3.56Å; I115-M131 WeakPolarHBondContact CA-O 3.28Å
116V97Very high95.5Very high1 Ų125 Ų251%0.00614%0.137CC..EExtended strand (participates in β ladder)trans-114133174.8172.80000109.7F105 V106 C107 M131 I136F105-V116 HydrophobicContact CD1-CG1 4.35Å; F105-V116 HydrophobicContact CD2-CG1 3.91Å; F105-V116 HydrophobicContact CE1-CG1 3.81Å; F105-V116 HydrophobicContact CE1-CG2 4.11Å; F105-V116 HydrophobicContact CE2-CG1 3.33Å; F105-V116 HydrophobicContact CG-CG1 4.39Å; F105-V116 HydrophobicContact CZ-CB 4.19Å; F105-V116 HydrophobicContact CZ-CG1 3.27Å; F105-V116 HydrophobicContact CZ-CG2 3.79Å; V106-V116 CarbonylContact O-C 3.48Å; V106-V116 WeakPolarHBondContact O-CA 3.42Å; C107-V116 HydrophobicContact CB-CG2 4.03Å; C107-V116 VanDerWaalsContact SG-CG2 3.54Å; V116-M131 HydrophobicContact CB-CB 4.11Å; V116-M131 HydrophobicContact CB-CE 4.36Å; V116-M131 HydrophobicContact CG1-CE 3.71Å; V116-M131 PolarHBondContact N-O 3.28Å; V116-I136 HydrophobicContact CG2-CD1 4.3Å; V116-I136 HydrophobicContact CG2-CG2 4.34Å
117S96.8Very high95.3Very high1 Ų129.3 Ų29.31%0.00716%0.159CC..EExtended strand (participates in β ladder)trans-120.4148.2171.3-52.20000110.3V106 K128 T129V106-S117 PolarHBondContact N-O 3.5Å; V106-S117 PolarHBondContact O-N 3.01Å; S117-K128 CarbonylContact C-O 3.56Å; S117-K128 VanDerWaalsContact CA-O 3.25Å; S117-K128 WeakPolarHBondContact CA-O 3.45Å; S117-T129 PolarHBondContact OG-OG1 3.46Å
118T96.7Very high95.1Very high11 Ų1133.7 Ų33.77%0.06718%0.178CC..EExtended strand (participates in β ladder)trans-109.2126.1165.6-61.70000108.1K99 N103 L104 L127 K128K99-T118 PolarHBondContact NZ-OG1 2.9Å; N103-T118 HydrophobicContact CB-CG2 4.03Å; L104-T118 CarbonylContact O-C 3.57Å; L104-T118 VanDerWaalsContact O-CA 3.23Å; L104-T118 WeakPolarHBondContact O-CA 3.26Å; T118-L127 HydrophobicContact CG2-CB 4.4Å; T118-L127 HydrophobicContact CG2-CD1 4.31Å; T118-L127 WeakPolarHBondContact O-CB 3.47Å; T118-L127 PolarHBondContact O-N 3.13Å; T118-K128 PolarHBondContact N-O 3.45Å; T118-K128 PolarHBondContact O-N 3.07Å; T118-K128 VanDerWaalsContact O-N 3.15Å
119L97.1Very high94.8Very high1 Ų137.5 Ų37.51%0.00520%0.202CC..EExtended strand (participates in β ladder)trans-117.2150-179.5-50.2178.3000110F45 L66 N103 L104 V106 E125 I126F45-L119 HydrophobicContact CD1-CD1 3.48Å; F45-L119 VanDerWaalsContact CD1-CD1 3.48Å; F45-L119 HydrophobicContact CE1-CD1 3.47Å; F45-L119 VanDerWaalsContact CE1-CD1 3.47Å; L66-L119 HydrophobicContact CD2-CD1 3.86Å; L66-L119 HydrophobicContact CD2-CD2 4.12Å; N103-L119 CarbonylContact C-O 3.54Å; N103-L119 WeakPolarHBondContact CA-O 3.28Å; N103-L119 WeakPolarHBondContact CB-O 3.47Å; L104-L119 HydrophobicContact CB-CB 4.31Å; L104-L119 PolarHBondContact N-O 3.4Å; L104-L119 PolarHBondContact O-N 2.8Å; V106-L119 HydrophobicContact CG2-CD1 3.81Å; V106-L119 HydrophobicContact CG2-CG 4.22Å; L119-E125 CarbonylContact C-O 3.48Å; L119-E125 VanDerWaalsContact CA-O 3.24Å; L119-E125 WeakPolarHBondContact CA-O 3.41Å; L119-I126 HydrophobicContact CD2-CB 3.96Å; L119-I126 HydrophobicContact CD2-CG1 3.57Å; L119-I126 HydrophobicContact CD2-CG2 4.18Å
120D95.2Very high94.3Very high37 Ų3740.3 Ų40.320%0.19823%0.231CC..  trans-68129.1166.9-178.2-64.5000109.5T122 N123 M124 E125 L127D120-T122 VanDerWaalsContact C-N 3.25Å; D120-T122 PolarHBondContact O-N 2.86Å; D120-T122 WeakPolarHBondContact OD1-CA 3.48Å; D120-T122 WeakPolarHBondContact OD1-CB 3.49Å; D120-T122 PolarHBondContact OD1-N 3.17Å; D120-T122 PolarHBondContact OD1-OG1 3.43Å; D120-N123 WeakPolarHBondContact CB-OD1 3.41Å; D120-N123 VanDerWaalsContact CG-OD1 3.31Å; D120-N123 PolarHBondContact OD1-N 2.85Å; D120-N123 VanDerWaalsContact OD1-N 3.09Å; D120-N123 PolarHBondContact OD1-OD1 2.85Å; D120-M124 WeakPolarHBondContact O-CA 3.35Å; D120-M124 PolarHBondContact O-N 2.83Å; D120-E125 PolarHBondContact N-O 3.47Å; D120-L127 HydrophobicContact CB-CD1 4.2Å; D120-L127 HydrophobicContact CB-CD2 4.29Å; D120-L127 HydrophobicContact CB-CG 4.27Å
121G92.4Very high94Very high4 Ų442.1 Ų42.14%0.04124%0.239CC..THydrogen-bonded Turntrans-66.6-26.3-177.600000113.6Y38Y38-G121 PolarHBondContact OH-O 3.22Å
122T90.9Very high93.9Very high90 Ų9046.1 Ų46.155%0.55227%0.267SS*.THydrogen-bonded Turntrans-84.8-53.3-175.569.40000112.4K47 D120K47-T122 PolarHBondContact NZ-O 2.94Å; D120-T122 VanDerWaalsContact C-N 3.25Å; D120-T122 PolarHBondContact O-N 2.86Å; D120-T122 WeakPolarHBondContact OD1-CA 3.48Å; D120-T122 WeakPolarHBondContact OD1-CB 3.49Å; D120-T122 PolarHBondContact OD1-N 3.17Å; D120-T122 PolarHBondContact OD1-OG1 3.43Å
123N91.6Very high93.9Very high42 Ų4245.6 Ų45.623%0.22526%0.264CS..THydrogen-bonded Turntrans-107.4-1.5-173.171.57.6000113.9Y64 D120 E125Y64-N123 WeakPolarHBondContact CD1-O 3.36Å; Y64-N123 VanDerWaalsContact CE1-O 3.24Å; Y64-N123 WeakPolarHBondContact CE1-O 3.43Å; D120-N123 WeakPolarHBondContact CB-OD1 3.41Å; D120-N123 VanDerWaalsContact CG-OD1 3.31Å; D120-N123 PolarHBondContact OD1-N 2.85Å; D120-N123 VanDerWaalsContact OD1-N 3.09Å; D120-N123 PolarHBondContact OD1-OD1 2.85Å; N123-E125 PolarHBondContact ND2-OE1 2.79Å; N123-E125 PolarHBondContact ND2-OE2 3.03Å; N123-E125 VanDerWaalsContact ND2-OE2 3.11Å; N123-E125 PolarHBondContact O-N 2.84Å; N123-E125 WeakPolarHBondContact OD1-CB 3.49Å; N123-E125 WeakPolarHBondContact OD1-CG 3.24Å; N123-E125 PolarHBondContact OD1-N 2.01Å
124M92.5Very high93.9Very high8 Ų845.8 Ų45.84%0.03927%0.269CS..  trans62.817.9178.3-61.4-91.4-69.400114.6Y38 F45 K47 Y64 L104 D120Y38-M124 HydrophobicContact CD1-SD 3.68Å; Y38-M124 HydrophobicContact CE1-SD 3.66Å; F45-M124 HydrophobicContact CD1-CE 3.13Å; F45-M124 HydrophobicContact CD1-SD 4.07Å; F45-M124 HydrophobicContact CE1-CE 3.18Å; F45-M124 HydrophobicContact CE1-SD 3.5Å; F45-M124 VanDerWaalsContact CE1-SD 3.5Å; F45-M124 HydrophobicContact CG-CE 3.91Å; F45-M124 HydrophobicContact CZ-CE 3.99Å; F45-M124 HydrophobicContact CZ-SD 4.2Å; K47-M124 HydrophobicContact CB-CE 4.2Å; K47-M124 HydrophobicContact CB-CG 4.08Å; K47-M124 HydrophobicContact CB-SD 4.07Å; K47-M124 HydrophobicContact CD-CG 4.21Å; Y64-M124 HydrophobicContact CD1-CB 4.47Å; Y64-M124 HydrophobicContact CD2-CG 4.42Å; Y64-M124 HydrophobicContact CG-CB 4.34Å; Y64-M124 HydrophobicContact CG-CG 4.15Å; L104-M124 HydrophobicContact CD1-SD 4Å; D120-M124 WeakPolarHBondContact O-CA 3.35Å; D120-M124 PolarHBondContact O-N 2.83Å
125E94.6Very high93.8Very high120 Ų12046 Ų4656%0.56127%0.271SS*.  trans-68.3142175.6-73.5177.4175.200111.6L119 D120 N123 L127L119-E125 CarbonylContact C-O 3.48Å; L119-E125 VanDerWaalsContact CA-O 3.24Å; L119-E125 WeakPolarHBondContact CA-O 3.41Å; D120-E125 PolarHBondContact N-O 3.47Å; N123-E125 PolarHBondContact ND2-OE1 2.79Å; N123-E125 PolarHBondContact ND2-OE2 3.03Å; N123-E125 VanDerWaalsContact ND2-OE2 3.11Å; N123-E125 PolarHBondContact O-N 2.84Å; N123-E125 WeakPolarHBondContact OD1-CB 3.49Å; N123-E125 WeakPolarHBondContact OD1-CG 3.24Å; N123-E125 PolarHBondContact OD1-N 2.01Å; E125-L127 PolarHBondContact O-N 3.19Å
126I96.2Very high93.8Very high88 Ų8844.7 Ų44.745%0.45126%0.264SS..EExtended strand (participates in β ladder)trans-76.7104.4178.5-53179.7000109.5L66 L119 T129L66-I126 HydrophobicContact CD1-CD1 4.42Å; L66-I126 HydrophobicContact CD2-CG1 4.27Å; L119-I126 HydrophobicContact CD2-CB 3.96Å; L119-I126 HydrophobicContact CD2-CG1 3.57Å; L119-I126 HydrophobicContact CD2-CG2 4.18Å; I126-T129 HydrophobicContact CG2-CG2 4.18Å
127L95.4Very high93.7Very high90 Ų9044.7 Ų44.747%0.47126%0.264SS..EExtended strand (participates in β ladder)trans-78.3-37.5176.6-57.8179000112N103 T118 D120 E125N103-L127 HydrophobicContact CB-CD1 4.41Å; N103-L127 WeakPolarHBondContact OD1-CD1 3.23Å; T118-L127 HydrophobicContact CG2-CB 4.4Å; T118-L127 HydrophobicContact CG2-CD1 4.31Å; T118-L127 WeakPolarHBondContact O-CB 3.47Å; T118-L127 PolarHBondContact O-N 3.13Å; D120-L127 HydrophobicContact CB-CD1 4.2Å; D120-L127 HydrophobicContact CB-CD2 4.29Å; D120-L127 HydrophobicContact CB-CG 4.27Å; E125-L127 PolarHBondContact O-N 3.19Å
128K92.9Very high93.7Very high91 Ų9144.8 Ų44.840%0.39627%0.265SS..EExtended strand (participates in β ladder)trans-152.3141.6178.2-170.3176.1-176.5-178.90110S117 T118 M131S117-K128 CarbonylContact C-O 3.56Å; S117-K128 VanDerWaalsContact CA-O 3.25Å; S117-K128 WeakPolarHBondContact CA-O 3.45Å; T118-K128 PolarHBondContact N-O 3.45Å; T118-K128 PolarHBondContact O-N 3.07Å; T118-K128 VanDerWaalsContact O-N 3.15Å; K128-M131 HydrophobicContact CD-CE 4.17Å; K128-M131 HydrophobicContact CD-SD 4.04Å
129T90.3Very high93.6Very high80 Ų8044.5 Ų44.549%0.49126%0.263SS..EExtended strand (participates in β ladder)trans-146.5170.2174.8-164.50000111.3S117 I126S117-T129 PolarHBondContact OG-OG1 3.46Å; I126-T129 HydrophobicContact CG2-CG2 4.18Å
130G85.4Confident93.5Very high59 Ų5945.6 Ų45.661%0.60827%0.269SS*.EExtended strand (participates in β ladder)trans87.36175.400000115.3
131M90.5Very high93.5Very high63 Ų6343.9 Ų43.931%0.3126%0.26SS..EExtended strand (participates in β ladder)trans-71.1137.4168.9-67.4-176.7-60.700109.1I115 V116 K128 G133I115-M131 CarbonylContact C-O 3.56Å; I115-M131 WeakPolarHBondContact CA-O 3.28Å; V116-M131 HydrophobicContact CB-CB 4.11Å; V116-M131 HydrophobicContact CB-CE 4.36Å; V116-M131 HydrophobicContact CG1-CE 3.71Å; V116-M131 PolarHBondContact N-O 3.28Å; K128-M131 HydrophobicContact CD-CE 4.17Å; K128-M131 HydrophobicContact CD-SD 4.04Å; M131-G133 PolarHBondContact O-N 3.28Å
132S93.6Very high93.6Very high84 Ų8447.6 Ų47.659%0.58728%0.279SS*.EExtended strand (participates in β ladder)trans-61.8130.6176-176.80000110.6A134S132-A134 VanDerWaalsContact C-N 3.35Å; S132-A134 WeakPolarHBondContact OG-CB 3.4Å; S132-A134 PolarHBondContact OG-N 2.98Å
133G95Very high93.8Very high0 Ų044.9 Ų44.90%026%0.261CS..  trans-91.77.7171.400000113.7P114 M131 A135 I136 C137P114-G133 WeakPolarHBondContact O-CA 3.23Å; P114-G133 PolarHBondContact O-N 2.86Å; M131-G133 PolarHBondContact O-N 3.28Å; G133-A135 PolarHBondContact O-N 2.99Å; G133-I136 WeakPolarHBondContact O-CB 3.34Å; G133-I136 PolarHBondContact O-N 2.82Å; G133-C137 PolarHBondContact O-N 3.35Å; G133-C137 VanDerWaalsContact O-N 3.15Å
134A94.7Very high93.9Very high45 Ų4545.3 Ų45.337%0.37226%0.263SS..THydrogen-bonded Turntrans-57.2133.5177.900000110.8S132 I136S132-A134 VanDerWaalsContact C-N 3.35Å; S132-A134 WeakPolarHBondContact OG-CB 3.4Å; S132-A134 PolarHBondContact OG-N 2.98Å; A134-I136 PolarHBondContact O-N 2.69Å; A134-I136 VanDerWaalsContact O-N 3.07Å
135A95.4Very high94.1Very high12 Ų1246 Ų4610%0.09927%0.272CS..THydrogen-bonded Turntrans58.45.8-171.400000116.2G133 S163 T165 V175 Y177G133-A135 PolarHBondContact O-N 2.99Å; A135-S163 PolarHBondContact O-OG 3.12Å; A135-T165 VanDerWaalsContact C-CG2 3.45Å; A135-T165 WeakPolarHBondContact O-CG2 3.1Å; A135-V175 HydrophobicContact CB-CG2 4.18Å; A135-Y177 HydrophobicContact CB-CD1 3.92Å; A135-Y177 HydrophobicContact CB-CD2 4.39Å; A135-Y177 HydrophobicContact CB-CE1 4.34Å; A135-Y177 HydrophobicContact CB-CG 3.94Å
136I96.9Very high94.3Very high12 Ų1241.2 Ų41.26%0.06225%0.251CS..THydrogen-bonded Turntrans-102.1-46.9177-63.3175.7000111.2F105 V116 G133 A134 V161 S163 Y177 P179F105-I136 HydrophobicContact CE1-CG2 3.99Å; F105-I136 HydrophobicContact CZ-CG2 4.15Å; V116-I136 HydrophobicContact CG2-CD1 4.3Å; V116-I136 HydrophobicContact CG2-CG2 4.34Å; G133-I136 WeakPolarHBondContact O-CB 3.34Å; G133-I136 PolarHBondContact O-N 2.82Å; A134-I136 PolarHBondContact O-N 2.69Å; A134-I136 VanDerWaalsContact O-N 3.07Å; I136-V161 HydrophobicContact CD1-CG1 4.29Å; I136-V161 HydrophobicContact CG2-CG1 4.14Å; I136-V161 HydrophobicContact CG2-CG2 4.45Å; I136-S163 VanDerWaalsContact O-CB 3.26Å; I136-S163 WeakPolarHBondContact O-CB 3.41Å; I136-Y177 HydrophobicContact CD1-CE1 4.45Å; I136-Y177 HydrophobicContact CG1-CD1 4.05Å; I136-Y177 HydrophobicContact CG1-CE1 3.92Å; I136-P179 HydrophobicContact CD1-CB 4.44Å; I136-P179 HydrophobicContact CD1-CG 4.33Å
137C94.4Very high94.4Very high1 Ų137.6 Ų37.61%0.00724%0.235CC..SBendtrans-133.5155.7172.766.50000110.5R94 C107 G133R94-C137 HydrophobicContact CB-CB 4.4Å; C107-C137 HydrophobicContact CB-CB 3.55Å; C107-C137 WeakPolarHBondContact CB-SG 3.27Å; C107-C137 WeakPolarHBondContact SG-CB 3.3Å; C107-C137 CovalentContact SG-SG 2.03Å; C107-C137 PolarHBondContact SG-SG 3.12Å; G133-C137 PolarHBondContact O-N 3.35Å; G133-C137 VanDerWaalsContact O-N 3.15Å
138P95.9Very high94.5Very high2 Ų234.2 Ų34.21%0.01322%0.218CC..  trans-64.7144.8-176.425.8-34000112R94 D143 T165 V166R94-P138 HydrophobicContact CB-CG 4.25Å; R94-P138 HydrophobicContact CG-CG 4.18Å; P138-D143 HydrophobicContact CB-CB 3.69Å; P138-T165 WeakPolarHBondContact CA-OG1 3.13Å; P138-T165 WeakPolarHBondContact CD-OG1 3.33Å; P138-V166 HydrophobicContact CB-CG2 4.1Å
139S95.2Very high94.7Very high5 Ų532.2 Ų32.24%0.03521%0.208CC..SBendtrans-73.4-36.8172-68.50000112.5T109 L112 P114T109-S139 WeakPolarHBondContact CB-O 3.26Å; L112-S139 WeakPolarHBondContact CD2-O 3.48Å; L112-S139 PolarHBondContact O-OG 3.03Å; P114-S139 WeakPolarHBondContact CD-OG 3.2Å; P114-S139 WeakPolarHBondContact CG-OG 3.34Å
140D94.7Very high95.1Very high25 Ų2528.4 Ų28.413%0.13418%0.184CC..SBendtrans-89.9130.6177.2-168.1-42.2000109.9K88 D142 D143K88-D140 VanDerWaalsContact CE-OD2 3.23Å; K88-D140 WeakPolarHBondContact CE-OD2 3.1Å; K88-D140 IonicContact NZ-OD2 2.71Å; K88-D140 PolarHBondContact NZ-OD2 3.09Å; D140-D142 PolarHBondContact O-N 3.37Å; D140-D142 PolarHBondContact OD1-N 3.28Å; D140-D143 HydrophobicContact CB-CB 4.1Å; D140-D143 PolarHBondContact O-N 3.04Å
141P94.9Very high95.6Very high0 Ų028.2 Ų28.20%017%0.167CC..THydrogen-bonded Turntrans-63-21.6177.826.2-36.2000114.9R26 L87 H92 R94 T109R26-P141 PolarHBondContact NH1-O 3.48Å; L87-P141 HydrophobicContact CG-CG 4.03Å; H92-P141 HydrophobicContact CB-CB 3.99Å; R94-P141 VanDerWaalsContact CZ-O 3.32Å; R94-P141 PolarHBondContact NE-O 3.17Å; T109-P141 HydrophobicContact CG2-CB 4.39Å
142D93.9Very high95.8Very high82 Ų8231.3 Ų31.344%0.43918%0.181SC..THydrogen-bonded Turntrans-91.3-9177.9-65.3-34000112.9R26 D140R26-D142 IonicContact CZ-OD1 3.61Å; R26-D142 IonicContact NH1-OD1 3.91Å; R26-D142 PolarHBondContact NH1-OD1 3.16Å; R26-D142 IonicContact NH2-OD1 3.77Å; R26-D142 PolarHBondContact NH2-OD1 2.99Å; D140-D142 PolarHBondContact O-N 3.37Å; D140-D142 PolarHBondContact OD1-N 3.28Å
143D95Very high95.9Very high33 Ų3328.9 Ų28.918%0.17617%0.169CC..SBendtrans-74.8139175.4-99.7-32.6000111.6R94 P138 D140 R174R94-D143 PolarHBondContact NH2-O 3.38Å; P138-D143 HydrophobicContact CB-CB 3.69Å; D140-D143 HydrophobicContact CB-CB 4.1Å; D140-D143 PolarHBondContact O-N 3.04Å; D143-R174 IonicContact OD1-CZ 2.89Å; D143-R174 IonicContact OD1-NH2 3.22Å; D143-R174 PolarHBondContact OD1-NH2 3.21Å; D143-R174 IonicContact OD2-NH2 2.7Å
144N95.1Very high96Very high52 Ų5229 Ų2928%0.27817%0.17SC..  trans-80.7135174.7-77.11.2000110.9N207N144-N207 WeakPolarHBondContact CB-OD1 3.44Å; N144-N207 VanDerWaalsContact CG-OD1 3.23Å; N144-N207 VanDerWaalsContact ND2-CG 3.35Å; N144-N207 PolarHBondContact ND2-ND2 3.4Å; N144-N207 PolarHBondContact ND2-OD1 3.39Å
145G96.5Very high96.1Very high22 Ų2227.5 Ų27.523%0.22716%0.156CC..  trans-157.3153.6175.100000110.1A164G145-A164 VanDerWaalsContact CA-O 3.29Å; G145-A164 WeakPolarHBondContact CA-O 3.03Å
146T98Very high96Very high19 Ų1930.1 Ų30.112%0.11718%0.184CC..EExtended strand (participates in β ladder)trans-134.4150.9177.2-173.50000109.9S163 A164 F208 A210 S211 F221T146-S163 CarbonylContact O-C 3.48Å; T146-S163 WeakPolarHBondContact O-CA 3.35Å; T146-A164 HydrophobicContact CG2-CB 3.97Å; T146-A164 PolarHBondContact N-O 3.32Å; T146-A164 PolarHBondContact O-N 2.99Å; T146-F208 HydrophobicContact CG2-CB 4.06Å; T146-A210 WeakPolarHBondContact OG1-CA 3.41Å; T146-S211 PolarHBondContact OG1-N 3.35Å; T146-S211 PolarHBondContact OG1-OG 2.81Å; T146-F221 HydrophobicContact CG2-CD1 4.27Å
147A98.2Very high95.9Very high13 Ų1335 Ų3511%0.10721%0.21CC..EExtended strand (participates in β ladder)trans-147.4153.8173.700000110.6T95 L97 V161 Y162 S211T95-A147 HydrophobicContact CG2-CB 3.9Å; L97-A147 HydrophobicContact CD1-CB 4.07Å; L97-A147 WeakPolarHBondContact CD2-O 3.31Å; A147-V161 HydrophobicContact CB-CG2 3.88Å; A147-Y162 CarbonylContact C-O 3.56Å; A147-Y162 WeakPolarHBondContact CA-O 3.35Å; A147-Y162 WeakPolarHBondContact CB-O 3.31Å; A147-S211 PolarHBondContact N-OG 3.48Å; A147-S211 PolarHBondContact O-OG 3.22Å
148V97.7Very high95.9Very high19 Ų1936 Ų3612%0.11522%0.216CC..EExtended strand (participates in β ladder)trans-138.8138.6177.561.80000109.5V150 V161 Y162 D213 V219V148-V150 HydrophobicContact CG1-CG2 4.44Å; V148-V161 WeakPolarHBondContact O-CA 3.03Å; V148-Y162 PolarHBondContact N-O 3.03Å; V148-Y162 PolarHBondContact O-N 2.83Å; V148-D213 HydrophobicContact CG2-CB 4.14Å; V148-V219 HydrophobicContact CG1-CG1 3.63Å
149W97.7Very high95.9Very high48 Ų4838.1 Ų38.118%0.18223%0.229CC..EExtended strand (participates in β ladder)trans-87126.2174.5-173.9-94.7000109.7L97 K99 F105 E151 P159 V161L97-W149 HydrophobicContact CB-CB 4.16Å; L97-W149 HydrophobicContact CD1-CB 4.26Å; K99-W149 HydrophobicContact CB-CZ2 4.28Å; K99-W149 HydrophobicContact CD-CH2 3.86Å; K99-W149 HydrophobicContact CD-CZ2 3.73Å; K99-W149 HydrophobicContact CD-CZ3 4.38Å; K99-W149 HydrophobicContact CG-CD2 3.92Å; K99-W149 HydrophobicContact CG-CE3 4.25Å; K99-W149 HydrophobicContact CG-CG 4.49Å; K99-W149 HydrophobicContact CG-CH2 4.13Å; K99-W149 HydrophobicContact CG-CZ2 3.75Å; K99-W149 HydrophobicContact CG-CZ3 4.36Å; F105-W149 HydrophobicContact CB-CE3 4.36Å; F105-W149 HydrophobicContact CB-CZ3 4.47Å; F105-W149 HydrophobicContact CD2-CE3 4.13Å; F105-W149 HydrophobicContact CD2-CH2 4.46Å; F105-W149 AromaticContact CD2-CZ3 3.56Å; F105-W149 HydrophobicContact CD2-CZ3 3.56Å; F105-W149 AromaticContact CE2-CZ3 3.97Å; F105-W149 HydrophobicContact CE2-CZ3 3.97Å; F105-W149 HydrophobicContact CG-CE3 4.27Å; F105-W149 HydrophobicContact CG-CZ3 4.16Å; W149-E151 PolarHBondContact NE1-OE2 3.23Å; W149-P159 HydrophobicContact CZ2-CB 3.62Å; W149-V161 HydrophobicContact CE3-CB 4.09Å; W149-V161 HydrophobicContact CZ3-CB 4.35Å
150V97.8Very high96Very high0 Ų038.2 Ų38.20%023%0.229CC..EExtended strand (participates in β ladder)trans-112.8110.2-179.8175.10000108.7V148 H152 N154 P159 S160 Y162 D213 V219 K246V148-V150 HydrophobicContact CG1-CG2 4.44Å; V150-H152 WeakPolarHBondContact CG1-O 3.44Å; V150-N154 PolarHBondContact O-ND2 2.82Å; V150-P159 VanDerWaalsContact O-CA 3.28Å; V150-P159 WeakPolarHBondContact O-CA 3Å; V150-S160 PolarHBondContact N-O 2.9Å; V150-S160 PolarHBondContact O-N 2.99Å; V150-Y162 HydrophobicContact CB-CD2 3.81Å; V150-Y162 HydrophobicContact CB-CE2 3.76Å; V150-Y162 HydrophobicContact CG1-CE2 4.12Å; V150-Y162 HydrophobicContact CG2-CD2 3.39Å; V150-Y162 HydrophobicContact CG2-CE2 3.71Å; V150-Y162 HydrophobicContact CG2-CG 4.3Å; V150-D213 HydrophobicContact CG2-CB 4.24Å; V150-V219 HydrophobicContact CG2-CG2 3.83Å; V150-K246 HydrophobicContact CG1-CD 3.75Å; V150-K246 HydrophobicContact CG1-CG 4.28Å
151E95.9Very high96.1Very high55 Ų5537.1 Ų37.126%0.25722%0.224SC..  trans-79.9-34.6-177.1-163.262.7-146.500112.5G100 W149 P159G100-E151 WeakPolarHBondContact CA-OE2 3.49Å; G100-E151 PolarHBondContact N-OE2 2.88Å; W149-E151 PolarHBondContact NE1-OE2 3.23Å; E151-P159 VanDerWaalsContact OE1-CG 3.29Å; E151-P159 WeakPolarHBondContact OE1-CG 3.28Å
152H96.3Very high96.3Very high129 Ų12937.1 Ų37.160%0.59722%0.224SC*.SBendtrans-135.3153.8-170.7-55.2-45.8000112.8V150 K246V150-H152 WeakPolarHBondContact CG1-O 3.44Å; H152-K246 WeakPolarHBondContact O-CD 3.39Å; H152-K246 PolarHBondContact O-NZ 3.23Å
153G95.6Very high96.5Very high32 Ų3233.2 Ų33.233%0.3320%0.203SC..SBendtrans93.7-7.4175.600000115.2K246G153-K246 CarbonylContact O-C 3.56Å; G153-K246 WeakPolarHBondContact O-CB 3.18Å
154N97Very high96.7Very high4 Ų431.7 Ų31.72%0.02120%0.195CC..SBendtrans-70.1158169.7-68.1-33.3000111.2V150 G156 N157 I158 S160 Y162 L181V150-N154 PolarHBondContact O-ND2 2.82Å; N154-G156 PolarHBondContact O-N 3.41Å; N154-N157 VanDerWaalsContact O-CA 3.31Å; N154-N157 WeakPolarHBondContact O-CA 3.43Å; N154-N157 PolarHBondContact O-N 3.47Å; N154-I158 WeakPolarHBondContact CB-O 3.23Å; N154-I158 PolarHBondContact ND2-O 2.95Å; N154-S160 PolarHBondContact ND2-N 3.06Å; N154-Y162 VanDerWaalsContact OD1-CE2 3.27Å; N154-Y162 WeakPolarHBondContact OD1-CE2 3.4Å; N154-Y162 PolarHBondContact OD1-OH 3.07Å; N154-L181 HydrophobicContact CB-CD1 4.11Å
155P95.8Very high96.8Very high13 Ų1329.2 Ų29.28%0.08418%0.181CC..G310 helixtrans-50.9130.3171.5-27.233.4000112.5N157 I158 L181 W190 K246 V249P155-N157 PolarHBondContact O-N 3.08Å; P155-I158 PolarHBondContact O-N 2.99Å; P155-L181 HydrophobicContact CB-CD1 4.1Å; P155-L181 HydrophobicContact CG-CD1 4.15Å; P155-W190 HydrophobicContact CB-CD2 3.64Å; P155-W190 VanDerWaalsContact CB-CE2 3.42Å; P155-W190 HydrophobicContact CB-CE3 4.24Å; P155-W190 HydrophobicContact CB-CG 3.9Å; P155-W190 HydrophobicContact CB-CH2 4.43Å; P155-W190 HydrophobicContact CB-CZ2 3.86Å; P155-W190 HydrophobicContact CG-CD2 4.42Å; P155-K246 WeakPolarHBondContact CD-O 3.28Å; P155-V249 HydrophobicContact CB-CG1 4.07Å; P155-V249 HydrophobicContact CG-CG1 3.44Å; P155-V249 VanDerWaalsContact CG-CG1 3.44Å
156G93.8Very high96.8Very high66 Ų6628.2 Ų28.268%0.6817%0.171SC*.G310 helixtrans67.311.2-174.500000114.9N154 I158N154-G156 PolarHBondContact O-N 3.41Å; G156-I158 PolarHBondContact O-N 3.19Å
157N93.8Very high96.6Very high115 Ų11528.2 Ų28.262%0.61517%0.171SC*.G310 helixtrans52.437-171.9-70.1-40.3000113.1N154 P155 P159N154-N157 VanDerWaalsContact O-CA 3.31Å; N154-N157 WeakPolarHBondContact O-CA 3.43Å; N154-N157 PolarHBondContact O-N 3.47Å; P155-N157 PolarHBondContact O-N 3.08Å; N157-P159 WeakPolarHBondContact O-CD 3.16Å
158I95.5Very high96.3Very high23 Ų2330.3 Ų30.312%0.11818%0.18CC..  trans-86.7119178.2-59.4172.8000108.8N154 P155 G156 L181 R182 Q189N154-I158 WeakPolarHBondContact CB-O 3.23Å; N154-I158 PolarHBondContact ND2-O 2.95Å; P155-I158 PolarHBondContact O-N 2.99Å; G156-I158 PolarHBondContact O-N 3.19Å; I158-L181 HydrophobicContact CB-CB 4.11Å; I158-L181 HydrophobicContact CD1-CB 3.98Å; I158-L181 HydrophobicContact CG2-CB 4Å; I158-L181 HydrophobicContact CG2-CD2 4.43Å; I158-R182 WeakPolarHBondContact CG2-O 3.37Å; I158-Q189 HydrophobicContact CD1-CB 3.97Å; I158-Q189 HydrophobicContact CD1-CG 4.22Å
159P95.7Very high95.9Very high46 Ų4635 Ų3530%0.29920%0.197SC..  trans-58.6144.7176.6-25.335.3000112.1W149 V150 E151 N157W149-P159 HydrophobicContact CZ2-CB 3.62Å; V150-P159 VanDerWaalsContact O-CA 3.28Å; V150-P159 WeakPolarHBondContact O-CA 3Å; E151-P159 VanDerWaalsContact OE1-CG 3.29Å; E151-P159 WeakPolarHBondContact OE1-CG 3.28Å; N157-P159 WeakPolarHBondContact O-CD 3.16Å
160S96.6Very high95.5Very high6 Ų636.6 Ų36.64%0.04221%0.212CC..EExtended strand (participates in β ladder)trans-155.6154.9179.3-159.20000112.3V150 N154 L181V150-S160 PolarHBondContact N-O 2.9Å; V150-S160 PolarHBondContact O-N 2.99Å; N154-S160 PolarHBondContact ND2-N 3.06Å; S160-L181 WeakPolarHBondContact OG-CD2 3.35Å
161V97.5Very high95.1Very high3 Ų337.8 Ų37.82%0.01822%0.224CC..EExtended strand (participates in β ladder)trans-82.1137.2168.164.30000109.5L97 F105 I136 A147 V148 W149 P179L97-V161 HydrophobicContact CD1-CG2 3.73Å; F105-V161 HydrophobicContact CE1-CB 4.35Å; F105-V161 HydrophobicContact CE1-CG1 4.26Å; F105-V161 HydrophobicContact CE1-CG2 4.26Å; F105-V161 HydrophobicContact CE2-CG1 4.31Å; F105-V161 HydrophobicContact CZ-CB 4.19Å; F105-V161 HydrophobicContact CZ-CG1 3.75Å; I136-V161 HydrophobicContact CD1-CG1 4.29Å; I136-V161 HydrophobicContact CG2-CG1 4.14Å; I136-V161 HydrophobicContact CG2-CG2 4.45Å; A147-V161 HydrophobicContact CB-CG2 3.88Å; V148-V161 WeakPolarHBondContact O-CA 3.03Å; W149-V161 HydrophobicContact CE3-CB 4.09Å; W149-V161 HydrophobicContact CZ3-CB 4.35Å; V161-P179 HydrophobicContact CG1-CG 3.78Å; V161-P179 WeakPolarHBondContact O-CD 3.29Å
162Y98.6Very high94.8Very high0 Ų038.1 Ų38.10%024%0.237CC..EExtended strand (participates in β ladder)trans-108.5133.9164.7-76.1-103.8000107.7A147 V148 V150 N154 R178 V219 I244 K246 W259A147-Y162 CarbonylContact C-O 3.56Å; A147-Y162 WeakPolarHBondContact CA-O 3.35Å; A147-Y162 WeakPolarHBondContact CB-O 3.31Å; V148-Y162 PolarHBondContact N-O 3.03Å; V148-Y162 PolarHBondContact O-N 2.83Å; V150-Y162 HydrophobicContact CB-CD2 3.81Å; V150-Y162 HydrophobicContact CB-CE2 3.76Å; V150-Y162 HydrophobicContact CG1-CE2 4.12Å; V150-Y162 HydrophobicContact CG2-CD2 3.39Å; V150-Y162 HydrophobicContact CG2-CE2 3.71Å; V150-Y162 HydrophobicContact CG2-CG 4.3Å; N154-Y162 VanDerWaalsContact OD1-CE2 3.27Å; N154-Y162 WeakPolarHBondContact OD1-CE2 3.4Å; N154-Y162 PolarHBondContact OD1-OH 3.07Å; Y162-R178 HydrophobicContact CD1-CB 4.12Å; Y162-R178 HydrophobicContact CD1-CG 4.47Å; Y162-R178 HydrophobicContact CE1-CB 4.03Å; Y162-R178 HydrophobicContact CE1-CG 4.18Å; Y162-R178 HydrophobicContact CE2-CG 4.18Å; Y162-R178 VanDerWaalsContact CZ-CD 3.47Å; Y162-R178 WeakPolarHBondContact OH-CD 3.05Å; Y162-V219 HydrophobicContact CD1-CG2 4.18Å; Y162-V219 HydrophobicContact CD2-CG2 4.26Å; Y162-V219 HydrophobicContact CE1-CG2 4.25Å; Y162-V219 HydrophobicContact CE2-CG2 4.36Å; Y162-V219 HydrophobicContact CG-CG2 4.15Å; Y162-I244 HydrophobicContact CD1-CD1 3.5Å; Y162-I244 VanDerWaalsContact CD1-CD1 3.5Å; Y162-I244 HydrophobicContact CE1-CD1 3.6Å; Y162-I244 HydrophobicContact CE1-CG1 4.5Å; Y162-K246 PolarHBondContact OH-O 2.94Å; Y162-W259 HydrophobicContact CD1-CH2 4.26Å; Y162-W259 HydrophobicContact CD1-CZ2 4.3Å; Y162-W259 AromaticContact CE1-CH2 3.51Å; Y162-W259 HydrophobicContact CE1-CH2 3.51Å; Y162-W259 AromaticContact CE1-CZ2 3.99Å; Y162-W259 HydrophobicContact CE1-CZ2 3.99Å; Y162-W259 HydrophobicContact CE1-CZ3 4.33Å
163S98.5Very high94.7Very high0 Ų036.9 Ų36.90%023%0.227CC..EExtended strand (participates in β ladder)trans-135149.3-170.9450000110.5A135 I136 T146 I176 Y177A135-S163 PolarHBondContact O-OG 3.12Å; I136-S163 VanDerWaalsContact O-CB 3.26Å; I136-S163 WeakPolarHBondContact O-CB 3.41Å; T146-S163 CarbonylContact O-C 3.48Å; T146-S163 WeakPolarHBondContact O-CA 3.35Å; S163-I176 CarbonylContact O-C 3.59Å; S163-I176 VanDerWaalsContact O-CA 3.29Å; S163-I176 WeakPolarHBondContact O-CA 3.5Å; S163-Y177 PolarHBondContact N-O 2.78Å; S163-Y177 PolarHBondContact O-N 3.46Å; S163-Y177 PolarHBondContact OG-O 3.18Å
164A98.5Very high94.8Very high0 Ų037.8 Ų37.80%022%0.221CC..EExtended strand (participates in β ladder)trans-136.4105.5172.900000108.6G145 T146 V175 I176 F208 F221G145-A164 VanDerWaalsContact CA-O 3.29Å; G145-A164 WeakPolarHBondContact CA-O 3.03Å; T146-A164 HydrophobicContact CG2-CB 3.97Å; T146-A164 PolarHBondContact N-O 3.32Å; T146-A164 PolarHBondContact O-N 2.99Å; A164-V175 VanDerWaalsContact CA-O 3.32Å; A164-V175 WeakPolarHBondContact CA-O 3.1Å; A164-I176 HydrophobicContact CB-CG1 3.74Å; A164-F208 HydrophobicContact CB-CB 4.02Å; A164-F208 HydrophobicContact CB-CD1 3.47Å; A164-F208 VanDerWaalsContact CB-CD1 3.47Å; A164-F208 HydrophobicContact CB-CD2 3.78Å; A164-F208 HydrophobicContact CB-CE1 3.74Å; A164-F208 HydrophobicContact CB-CE2 3.97Å; A164-F208 HydrophobicContact CB-CG 3.5Å; A164-F208 VanDerWaalsContact CB-CG 3.5Å; A164-F208 HydrophobicContact CB-CZ 3.96Å; A164-F208 WeakPolarHBondContact O-CB 3.28Å; A164-F208 WeakPolarHBondContact O-CD2 3.43Å; A164-F221 HydrophobicContact CB-CD1 3.61Å; A164-F221 HydrophobicContact CB-CE1 3.79Å
165T97.8Very high94.9Very high0 Ų037.7 Ų37.70%022%0.22CC..EExtended strand (participates in β ladder)trans-163-177.5-171.6-171.10000111.2A135 P138 R174 V175A135-T165 VanDerWaalsContact C-CG2 3.45Å; A135-T165 WeakPolarHBondContact O-CG2 3.1Å; P138-T165 WeakPolarHBondContact CA-OG1 3.13Å; P138-T165 WeakPolarHBondContact CD-OG1 3.33Å; T165-R174 WeakPolarHBondContact O-CA 3.35Å; T165-V175 PolarHBondContact N-O 2.81Å; T165-V175 VanDerWaalsContact N-O 3.17Å; T165-V175 PolarHBondContact O-N 3.05Å
166V96.1Very high95Very high1 Ų137.1 Ų37.11%0.00622%0.216CC..EExtended strand (participates in β ladder)trans-67.4147.4169.8-67.50000112P138 Y173 R174P138-V166 HydrophobicContact CB-CG2 4.1Å; V166-Y173 CarbonylContact C-O 3.6Å; V166-Y173 WeakPolarHBondContact CA-O 3.45Å; V166-R174 HydrophobicContact CG1-CG 3.74Å
167T94.8Very high95.2Very high20 Ų2035.8 Ų35.812%0.12319%0.191CC..SBendtrans-76.5-33.1178.6520000113.2Y173 V175T167-Y173 PolarHBondContact N-O 3.34Å; T167-Y173 PolarHBondContact OG1-O 2.91Å; T167-V175 HydrophobicContact CG2-CB 4.5Å; T167-V175 HydrophobicContact CG2-CG1 4.02Å; T167-V175 HydrophobicContact CG2-CG2 3.67Å
168D91.4Very high95.4Very high56 Ų5630.4 Ų30.430%0.29916%0.162SC..SBendtrans-155.2-177.8-17560.651.9000111.4T170 G171D168-T170 PolarHBondContact O-N 3.09Å; D168-T170 WeakPolarHBondContact OD1-CA 3.39Å; D168-T170 VanDerWaalsContact OD1-CB 3.27Å; D168-T170 WeakPolarHBondContact OD1-CB 3.48Å; D168-T170 WeakPolarHBondContact OD1-CG2 3.25Å; D168-T170 PolarHBondContact OD1-N 3.3Å; D168-T170 PolarHBondContact OD1-OG1 3.49Å; D168-G171 PolarHBondContact O-N 3.17Å
169Y88.6Confident95.4Very high119 Ų11930.2 Ų30.247%0.46716%0.163SC..THydrogen-bonded Turntrans-69.6-13.6-176.672.9-88.9000114.9R81R81-Y169 HydrophobicContact CG-CE2 4.38Å
170T90.1Very high95.4Very high80 Ų8029.3 Ų29.349%0.49116%0.157SC..THydrogen-bonded Turntrans-76-20.1177.971.80000111.6D168 A172D168-T170 PolarHBondContact O-N 3.09Å; D168-T170 WeakPolarHBondContact OD1-CA 3.39Å; D168-T170 VanDerWaalsContact OD1-CB 3.27Å; D168-T170 WeakPolarHBondContact OD1-CB 3.48Å; D168-T170 WeakPolarHBondContact OD1-CG2 3.25Å; D168-T170 PolarHBondContact OD1-N 3.3Å; D168-T170 PolarHBondContact OD1-OG1 3.49Å; T170-A172 PolarHBondContact O-N 2.99Å; T170-A172 VanDerWaalsContact OG1-CB 3.28Å; T170-A172 WeakPolarHBondContact OG1-CB 3.38Å; T170-A172 PolarHBondContact OG1-N 3.37Å
171G88.5Confident95.4Very high25 Ų2529.1 Ų29.126%0.25816%0.155SC..  trans67.28.7-174.600000114D168 Y173D168-G171 PolarHBondContact O-N 3.17Å; G171-Y173 PolarHBondContact O-N 2.84Å
172A90.4Very high95.1Very high63 Ų6334.4 Ų34.452%0.52118%0.175SC..  trans-65.7-36.4-173.100000113.3T170T170-A172 PolarHBondContact O-N 2.99Å; T170-A172 VanDerWaalsContact OG1-CB 3.28Å; T170-A172 WeakPolarHBondContact OG1-CB 3.38Å; T170-A172 PolarHBondContact OG1-N 3.37Å
173Y94.8Very high94.5Very high102 Ų10241.7 Ų41.740%0.421%0.207SC..  trans-125.8140.7-178.9-51-60.6000111.5V166 T167 G171 A198V166-Y173 CarbonylContact C-O 3.6Å; V166-Y173 WeakPolarHBondContact CA-O 3.45Å; T167-Y173 PolarHBondContact N-O 3.34Å; T167-Y173 PolarHBondContact OG1-O 2.91Å; G171-Y173 PolarHBondContact O-N 2.84Å; Y173-A198 HydrophobicContact CD1-CB 3.97Å; Y173-A198 HydrophobicContact CE1-CB 3.56Å
174R97Very high93.6Very high52 Ų5244.9 Ų44.920%0.19624%0.239CC..EExtended strand (participates in β ladder)trans-129128179.9-66-176.2179.9-127.9-13.2108.5D143 T165 V166 P206 F208D143-R174 IonicContact OD1-CZ 2.89Å; D143-R174 IonicContact OD1-NH2 3.22Å; D143-R174 PolarHBondContact OD1-NH2 3.21Å; D143-R174 IonicContact OD2-NH2 2.7Å; T165-R174 WeakPolarHBondContact O-CA 3.35Å; V166-R174 HydrophobicContact CG1-CG 3.74Å; R174-P206 HydrophobicContact CB-CG 3.61Å; R174-P206 WeakPolarHBondContact CD-O 3.31Å; R174-P206 HydrophobicContact CG-CG 4.45Å; R174-P206 PolarHBondContact NH1-O 2.89Å; R174-F208 HydrophobicContact CB-CE2 3.96Å
175V97.9Very high92.3Very high2 Ų252.6 Ų52.61%0.01228%0.275CS..EExtended strand (participates in β ladder)trans-137.7153.8-170.1-64.30000111.4A135 A164 T165 T167 T195 Q197A135-V175 HydrophobicContact CB-CG2 4.18Å; A164-V175 VanDerWaalsContact CA-O 3.32Å; A164-V175 WeakPolarHBondContact CA-O 3.1Å; T165-V175 PolarHBondContact N-O 2.81Å; T165-V175 VanDerWaalsContact N-O 3.17Å; T165-V175 PolarHBondContact O-N 3.05Å; T167-V175 HydrophobicContact CG2-CB 4.5Å; T167-V175 HydrophobicContact CG2-CG1 4.02Å; T167-V175 HydrophobicContact CG2-CG2 3.67Å; V175-T195 WeakPolarHBondContact CA-OG1 3.35Å; V175-T195 WeakPolarHBondContact CB-OG1 3.41Å; V175-Q197 HydrophobicContact CG1-CG 3.99Å
176I98.5Very high91Very high0 Ų060.5 Ų60.50%031%0.312CS..EExtended strand (participates in β ladder)trans-93.3121.2159.9-64.9161.1000107.4S163 A164 S194 T195 F208 F221 I244 W259 F262S163-I176 CarbonylContact O-C 3.59Å; S163-I176 VanDerWaalsContact O-CA 3.29Å; S163-I176 WeakPolarHBondContact O-CA 3.5Å; A164-I176 HydrophobicContact CB-CG1 3.74Å; I176-S194 CarbonylContact O-C 3.57Å; I176-S194 VanDerWaalsContact O-CA 3.23Å; I176-S194 WeakPolarHBondContact O-CA 3.26Å; I176-T195 HydrophobicContact CB-CG2 3.92Å; I176-T195 HydrophobicContact CD1-CG2 4.39Å; I176-T195 HydrophobicContact CG1-CG2 4.49Å; I176-T195 PolarHBondContact N-OG1 3.45Å; I176-T195 VanDerWaalsContact N-OG1 3.11Å; I176-T195 PolarHBondContact O-N 3.17Å; I176-F208 HydrophobicContact CD1-CE1 4.35Å; I176-F208 HydrophobicContact CG1-CE1 3.98Å; I176-F208 HydrophobicContact CG1-CZ 4.22Å; I176-F221 HydrophobicContact CD1-CB 4.29Å; I176-F221 HydrophobicContact CD1-CD1 4.5Å; I176-F221 HydrophobicContact CD1-CD2 4.05Å; I176-F221 HydrophobicContact CD1-CG 4.02Å; I176-F221 HydrophobicContact CG1-CD1 4.33Å; I176-F221 HydrophobicContact CG1-CE1 4.49Å; I176-F221 HydrophobicContact CG1-CG 4.34Å; I176-F221 HydrophobicContact CG2-CD2 4.18Å; I176-F221 HydrophobicContact CG2-CE1 3.95Å; I176-F221 HydrophobicContact CG2-CE2 3.58Å; I176-F221 HydrophobicContact CG2-CZ 3.43Å; I176-F221 VanDerWaalsContact CG2-CZ 3.43Å; I176-I244 HydrophobicContact CG2-CD1 4Å; I176-W259 PolarHBondContact O-NE1 3.25Å; I176-F262 HydrophobicContact CD1-CD2 4.2Å; I176-F262 HydrophobicContact CD1-CE2 3.57Å
177Y98.4Very high90.4Very high39 Ų3964.9 Ų64.915%0.15334%0.336CS..EExtended strand (participates in β ladder)trans-131.5141.4-165.8176.2-107000112.3A135 I136 S163 P179 Y192 M193A135-Y177 HydrophobicContact CB-CD1 3.92Å; A135-Y177 HydrophobicContact CB-CD2 4.39Å; A135-Y177 HydrophobicContact CB-CE1 4.34Å; A135-Y177 HydrophobicContact CB-CG 3.94Å; I136-Y177 HydrophobicContact CD1-CE1 4.45Å; I136-Y177 HydrophobicContact CG1-CD1 4.05Å; I136-Y177 HydrophobicContact CG1-CE1 3.92Å; S163-Y177 PolarHBondContact N-O 2.78Å; S163-Y177 PolarHBondContact O-N 3.46Å; S163-Y177 PolarHBondContact OG-O 3.18Å; Y177-P179 HydrophobicContact CE1-CB 3.81Å; Y177-P179 HydrophobicContact CE1-CG 4.44Å; Y177-P179 WeakPolarHBondContact OH-CA 3.33Å; Y177-Y192 HydrophobicContact CD2-CD2 4.29Å; Y177-Y192 AromaticContact CE2-CD2 3.7Å; Y177-Y192 HydrophobicContact CE2-CD2 3.7Å; Y177-Y192 AromaticContact CE2-CG 3.93Å; Y177-Y192 HydrophobicContact CE2-CG 3.93Å; Y177-M193 WeakPolarHBondContact CA-O 3.48Å; Y177-M193 WeakPolarHBondContact CD2-O 3.33Å
178R97.9Very high90.2Very high1 Ų167.1 Ų67.10%0.00435%0.349CS..EExtended strand (participates in β ladder)trans-123.5125.1164.9-176.4-168.575.1-155.40.2108.3Y162 L181 Y192 M193 K246 D248 W259Y162-R178 HydrophobicContact CD1-CB 4.12Å; Y162-R178 HydrophobicContact CD1-CG 4.47Å; Y162-R178 HydrophobicContact CE1-CB 4.03Å; Y162-R178 HydrophobicContact CE1-CG 4.18Å; Y162-R178 HydrophobicContact CE2-CG 4.18Å; Y162-R178 VanDerWaalsContact CZ-CD 3.47Å; Y162-R178 WeakPolarHBondContact OH-CD 3.05Å; R178-L181 HydrophobicContact CG-CD2 4.41Å; R178-Y192 VanDerWaalsContact O-CA 3.28Å; R178-Y192 WeakPolarHBondContact O-CA 3.41Å; R178-Y192 WeakPolarHBondContact O-CB 3.05Å; R178-M193 HydrophobicContact CB-CB 4.42Å; R178-M193 PolarHBondContact N-O 3.37Å; R178-M193 PolarHBondContact O-N 3.06Å; R178-K246 PolarHBondContact NH1-O 3.03Å; R178-D248 PolarHBondContact NH1-O 3.28Å; R178-D248 VanDerWaalsContact NH1-O 3.13Å; R178-W259 HydrophobicContact CB-CH2 3.65Å; R178-W259 HydrophobicContact CB-CZ2 3.66Å; R178-W259 HydrophobicContact CG-CH2 4.48Å
179P96.3Very high90.2Very high20 Ų2068.8 Ų68.813%0.1336%0.355CS..PPolyproline II helixtrans-67.2166.7176.928.5-31.6000112.2I136 V161 Y177 L181I136-P179 HydrophobicContact CD1-CB 4.44Å; I136-P179 HydrophobicContact CD1-CG 4.33Å; V161-P179 HydrophobicContact CG1-CG 3.78Å; V161-P179 WeakPolarHBondContact O-CD 3.29Å; Y177-P179 HydrophobicContact CE1-CB 3.81Å; Y177-P179 HydrophobicContact CE1-CG 4.44Å; Y177-P179 WeakPolarHBondContact OH-CA 3.33Å; P179-L181 PolarHBondContact O-N 2.97Å
180P96Very high90.5Very high27 Ų2766.7 Ų66.718%0.17535%0.346CS..PPolyproline II helixtrans-57.8134.4178-19.830.2000111.6R182 V188 W190P180-R182 PolarHBondContact O-N 3.22Å; P180-R182 PolarHBondContact O-NH1 3.45Å; P180-V188 HydrophobicContact CB-CG1 3.8Å; P180-V188 HydrophobicContact CB-CG2 4.4Å; P180-W190 CarbonylContact C-O 3.56Å; P180-W190 WeakPolarHBondContact CA-O 3.14Å; P180-W190 WeakPolarHBondContact CB-O 3.44Å
181L95.8Very high90.8Very high1 Ų165.1 Ų65.11%0.00534%0.337CS..EExtended strand (participates in β ladder)trans-81118.9178.4-54.7-179.1000108.8N154 P155 I158 S160 R178 P179 Q189 W190N154-L181 HydrophobicContact CB-CD1 4.11Å; P155-L181 HydrophobicContact CB-CD1 4.1Å; P155-L181 HydrophobicContact CG-CD1 4.15Å; I158-L181 HydrophobicContact CB-CB 4.11Å; I158-L181 HydrophobicContact CD1-CB 3.98Å; I158-L181 HydrophobicContact CG2-CB 4Å; I158-L181 HydrophobicContact CG2-CD2 4.43Å; S160-L181 WeakPolarHBondContact OG-CD2 3.35Å; R178-L181 HydrophobicContact CG-CD2 4.41Å; P179-L181 PolarHBondContact O-N 2.97Å; L181-Q189 PolarHBondContact O-N 2.96Å; L181-W190 HydrophobicContact CB-CB 4Å; L181-W190 HydrophobicContact CB-CG 4.46Å; L181-W190 HydrophobicContact CD1-CB 4.1Å; L181-W190 HydrophobicContact CD1-CG 4.22Å; L181-W190 HydrophobicContact CG-CB 4.18Å; L181-W190 PolarHBondContact N-O 3.44Å; L181-W190 PolarHBondContact O-N 3.5Å
182R91.8Very high91.2Very high115 Ų11568.2 Ų68.243%0.43434%0.342SS..EExtended strand (participates in β ladder)trans-113.2138.5-177.3-68.7179.4175.284.3-4.2110.6I158 P180 D187 V188I158-R182 WeakPolarHBondContact CG2-O 3.37Å; P180-R182 PolarHBondContact O-N 3.22Å; P180-R182 PolarHBondContact O-NH1 3.45Å; R182-D187 VanDerWaalsContact CA-O 3.29Å; R182-D187 WeakPolarHBondContact CA-O 3.24Å; R182-V188 HydrophobicContact CG-CG2 3.9Å
183K84.9Confident91.5Very high153 Ų15365.2 Ų65.267%0.66532%0.317SS*.EExtended strand (participates in β ladder)trans-101.9113.9168-168.7176.6-178.2-179.30108D187 Q189K183-D187 PolarHBondContact N-O 2.82Å; K183-Q189 HydrophobicContact CB-CG 3.95Å
184G80Confident91.7Very high66 Ų6661 Ų6168%0.6830%0.303SS*.THydrogen-bonded Turntrans74.7-154.8-170.600000112.5
185Q71.1Confident91.7Very high162 Ų16258.5 Ų58.576%0.75729%0.293SS*.THydrogen-bonded Turntrans-77.9-32.4-171.4-75.3-173-25.700114.3
186E70.1Confident91.6Very high167 Ų16760.1 Ų60.178%0.7830%0.301SS*.THydrogen-bonded Turntrans-132.5-24.6-165.6-62.4-167.5158.900115.9V188E186-V188 PolarHBondContact O-N 3.36Å; E186-V188 VanDerWaalsContact O-N 3.07Å
187D84.5Confident91.2Very high93 Ų9365.4 Ų65.450%0.49733%0.326SS..EExtended strand (participates in β ladder)trans-79.3102.8-172-168.718000112R182 K183 Q189R182-D187 VanDerWaalsContact CA-O 3.29Å; R182-D187 WeakPolarHBondContact CA-O 3.24Å; K183-D187 PolarHBondContact N-O 2.82Å; D187-Q189 PolarHBondContact O-N 3.29Å; D187-Q189 PolarHBondContact OD2-NE2 2.84Å
188V90Very high90.6Very high66 Ų6667.4 Ų67.440%0.435%0.351SS..EExtended strand (participates in β ladder)trans-74.2102.3175.5177.90000108.8P180 R182 E186 W190P180-V188 HydrophobicContact CB-CG1 3.8Å; P180-V188 HydrophobicContact CB-CG2 4.4Å; R182-V188 HydrophobicContact CG-CG2 3.9Å; E186-V188 PolarHBondContact O-N 3.36Å; E186-V188 VanDerWaalsContact O-N 3.07Å; V188-W190 WeakPolarHBondContact CG1-O 3.48Å
189Q92.2Very high90.3Very high92 Ų9269 Ų6943%0.4336%0.359SS..EExtended strand (participates in β ladder)trans-79.6-36.7178.3-70.9-71.5-43.500111.5I158 L181 K183 D187I158-Q189 HydrophobicContact CD1-CB 3.97Å; I158-Q189 HydrophobicContact CD1-CG 4.22Å; L181-Q189 PolarHBondContact O-N 2.96Å; K183-Q189 HydrophobicContact CB-CG 3.95Å; D187-Q189 PolarHBondContact O-N 3.29Å; D187-Q189 PolarHBondContact OD2-NE2 2.84Å
190W95.1Very high90.1Very high75 Ų7570.9 Ų70.928%0.28437%0.373SS..EExtended strand (participates in β ladder)trans-135.6139.6179.1-56.386000110.9P155 P180 L181 V188 V249P155-W190 HydrophobicContact CB-CD2 3.64Å; P155-W190 VanDerWaalsContact CB-CE2 3.42Å; P155-W190 HydrophobicContact CB-CE3 4.24Å; P155-W190 HydrophobicContact CB-CG 3.9Å; P155-W190 HydrophobicContact CB-CH2 4.43Å; P155-W190 HydrophobicContact CB-CZ2 3.86Å; P155-W190 HydrophobicContact CG-CD2 4.42Å; P180-W190 CarbonylContact C-O 3.56Å; P180-W190 WeakPolarHBondContact CA-O 3.14Å; P180-W190 WeakPolarHBondContact CB-O 3.44Å; L181-W190 HydrophobicContact CB-CB 4Å; L181-W190 HydrophobicContact CB-CG 4.46Å; L181-W190 HydrophobicContact CD1-CB 4.1Å; L181-W190 HydrophobicContact CD1-CG 4.22Å; L181-W190 HydrophobicContact CG-CB 4.18Å; L181-W190 PolarHBondContact N-O 3.44Å; L181-W190 PolarHBondContact O-N 3.5Å; V188-W190 WeakPolarHBondContact CG1-O 3.48Å; W190-V249 HydrophobicContact CD2-CG1 4.36Å; W190-V249 HydrophobicContact CE3-CB 4.03Å; W190-V249 HydrophobicContact CE3-CG1 3.53Å; W190-V249 HydrophobicContact CH2-CG1 4.11Å; W190-V249 HydrophobicContact CZ3-CB 3.82Å; W190-V249 HydrophobicContact CZ3-CG1 3.39Å; W190-V249 HydrophobicContact CZ3-CG2 4.32Å
191P95.6Very high89.8Confident47 Ų4773.1 Ų73.131%0.30538%0.38SS..  trans-65.8169.1176.830.6-35.8000111.5Q257P191-Q257 HydrophobicContact CB-CG 3.92Å; P191-Q257 VanDerWaalsContact CB-NE2 3.32Å; P191-Q257 HydrophobicContact CG-CG 4.1Å
192Y96.8Very high89.8Confident89 Ų8973 Ų7335%0.34938%0.379SS..  trans-60.9161.5167.574.6-89.6000111Y177 R178 Q257Y177-Y192 HydrophobicContact CD2-CD2 4.29Å; Y177-Y192 AromaticContact CE2-CD2 3.7Å; Y177-Y192 HydrophobicContact CE2-CD2 3.7Å; Y177-Y192 AromaticContact CE2-CG 3.93Å; Y177-Y192 HydrophobicContact CE2-CG 3.93Å; R178-Y192 VanDerWaalsContact O-CA 3.28Å; R178-Y192 WeakPolarHBondContact O-CA 3.41Å; R178-Y192 WeakPolarHBondContact O-CB 3.05Å; Y192-Q257 HydrophobicContact CE2-CB 4.11Å; Y192-Q257 PolarHBondContact OH-OE1 2.8Å; Y192-Q257 VanDerWaalsContact OH-OE1 3.14Å
193M97.9Very high90Very high1 Ų168.3 Ų68.31%0.00536%0.363CS..EExtended strand (participates in β ladder)trans-132.8138.6174-71.2-68.6-69.800109.5Y177 R178 G250 Q257 T258 W259Y177-M193 WeakPolarHBondContact CA-O 3.48Å; Y177-M193 WeakPolarHBondContact CD2-O 3.33Å; R178-M193 HydrophobicContact CB-CB 4.42Å; R178-M193 PolarHBondContact N-O 3.37Å; R178-M193 PolarHBondContact O-N 3.06Å; M193-G250 VanDerWaalsContact CE-N 3.26Å; M193-Q257 WeakPolarHBondContact CA-O 3.38Å; M193-Q257 VanDerWaalsContact SD-C 3.59Å; M193-T258 VanDerWaalsContact CE-O 3.31Å; M193-T258 WeakPolarHBondContact CE-O 3.35Å; M193-W259 HydrophobicContact CB-CD2 3.96Å; M193-W259 HydrophobicContact CB-CE3 3.9Å; M193-W259 HydrophobicContact CB-CH2 3.27Å; M193-W259 HydrophobicContact CB-CZ2 3.32Å; M193-W259 HydrophobicContact CB-CZ3 3.58Å; M193-W259 HydrophobicContact CE-CD2 4Å; M193-W259 HydrophobicContact CE-CE3 3.48Å; M193-W259 VanDerWaalsContact CE-CE3 3.48Å; M193-W259 HydrophobicContact CE-CZ3 3.91Å; M193-W259 HydrophobicContact CG-CE3 4.28Å; M193-W259 HydrophobicContact CG-CH2 3.94Å; M193-W259 HydrophobicContact CG-CZ2 4.44Å; M193-W259 HydrophobicContact CG-CZ3 3.85Å
194S97.6Very high90.5Very high13 Ų1364.8 Ų64.89%0.09135%0.347CS..EExtended strand (participates in β ladder)trans-141.3166.8175.574.20000113.3I176 Q257 T258 W259I176-S194 CarbonylContact O-C 3.57Å; I176-S194 VanDerWaalsContact O-CA 3.23Å; I176-S194 WeakPolarHBondContact O-CA 3.26Å; S194-Q257 PolarHBondContact N-O 2.89Å; S194-T258 VanDerWaalsContact O-CA 3.24Å; S194-T258 WeakPolarHBondContact O-CA 3.19Å; S194-T258 WeakPolarHBondContact O-CG2 3.39Å; S194-W259 PolarHBondContact O-N 3.06Å; S194-W259 VanDerWaalsContact O-N 3.08Å
195T97.7Very high91.1Very high0 Ų068.5 Ų68.50%035%0.347CS..PPolyproline II helixtrans-69161.1158.248.70000110.3V175 I176 Q197 W202 L203 W259 F262V175-T195 WeakPolarHBondContact CA-OG1 3.35Å; V175-T195 WeakPolarHBondContact CB-OG1 3.41Å; I176-T195 HydrophobicContact CB-CG2 3.92Å; I176-T195 HydrophobicContact CD1-CG2 4.39Å; I176-T195 HydrophobicContact CG1-CG2 4.49Å; I176-T195 PolarHBondContact N-OG1 3.45Å; I176-T195 VanDerWaalsContact N-OG1 3.11Å; I176-T195 PolarHBondContact O-N 3.17Å; T195-Q197 PolarHBondContact O-N 3.31Å; T195-W202 HydrophobicContact CG2-CE3 3.9Å; T195-W202 HydrophobicContact CG2-CZ3 4.2Å; T195-L203 HydrophobicContact CG2-CD1 4.15Å; T195-W259 VanDerWaalsContact N-CD1 3.34Å; T195-F262 HydrophobicContact CG2-CD2 3.99Å; T195-F262 HydrophobicContact CG2-CE2 4.14Å; T195-F262 HydrophobicContact CG2-CG 4.24Å; T195-F262 HydrophobicContact CG2-CZ 4.49Å
196I94.9Very high92.4Very high35 Ų3561 Ų6118%0.17931%0.312CS..PPolyproline II helixtrans-63.3129.1174.6-56.5178.8000109.3D199 W202 L255 T258 K372I196-D199 HydrophobicContact CB-CB 3.99Å; I196-D199 HydrophobicContact CG2-CB 3.68Å; I196-W202 HydrophobicContact CB-CD2 4.34Å; I196-W202 HydrophobicContact CD1-CD2 4.16Å; I196-W202 VanDerWaalsContact CD1-CE2 3.49Å; I196-W202 HydrophobicContact CD1-CH2 4.21Å; I196-W202 HydrophobicContact CD1-CZ2 3.54Å; I196-W202 HydrophobicContact CG1-CD2 4.08Å; I196-W202 HydrophobicContact CG1-CE3 4.32Å; I196-W202 HydrophobicContact CG1-CH2 4.06Å; I196-W202 HydrophobicContact CG1-CZ2 3.88Å; I196-W202 HydrophobicContact CG1-CZ3 4.31Å; I196-L255 HydrophobicContact CD1-CD2 3.8Å; I196-L255 HydrophobicContact CG1-CD2 4.33Å; I196-T258 HydrophobicContact CD1-CG2 4.47Å; I196-T258 HydrophobicContact CG1-CG2 3.58Å; I196-K372 HydrophobicContact CD1-CD 4.37Å; I196-K372 HydrophobicContact CD1-CG 3.84Å
197Q90.1Very high93.6Very high112 Ų11254.7 Ų54.752%0.52328%0.284SS..THydrogen-bonded Turntrans-72140.3174.5-66179.5-8.400110.2V175 T195 D199V175-Q197 HydrophobicContact CG1-CG 3.99Å; T195-Q197 PolarHBondContact O-N 3.31Å; Q197-D199 PolarHBondContact O-N 3.27Å; Q197-D199 VanDerWaalsContact O-N 3.15Å
198A86.6Confident94.3Very high81 Ų8150.3 Ų50.367%0.66926%0.261SS*.THydrogen-bonded Turntrans61.315.5175.800000116.4Y173Y173-A198 HydrophobicContact CD1-CB 3.97Å; Y173-A198 HydrophobicContact CE1-CB 3.56Å
199D91.4Very high94.7Very high33 Ų3348.1 Ų48.118%0.17625%0.246CC..  trans-98.2105176-165.4-32.9000111.5I196 Q197 K201 W202 L203I196-D199 HydrophobicContact CB-CB 3.99Å; I196-D199 HydrophobicContact CG2-CB 3.68Å; Q197-D199 PolarHBondContact O-N 3.27Å; Q197-D199 VanDerWaalsContact O-N 3.15Å; D199-K201 PolarHBondContact O-N 3.4Å; D199-K201 VanDerWaalsContact O-N 3.16Å; D199-K201 VanDerWaalsContact OD1-CB 3.29Å; D199-K201 WeakPolarHBondContact OD1-CB 3.34Å; D199-K201 PolarHBondContact OD1-N 2.91Å; D199-W202 WeakPolarHBondContact O-CB 3.28Å; D199-W202 PolarHBondContact O-N 3.07Å; D199-L203 PolarHBondContact O-N 2.9Å
200S91Very high95Very high60 Ų6044.1 Ų44.142%0.4223%0.229SC..THydrogen-bonded Turntrans-60.7-22.3179.864.20000114.4W202 V228S200-W202 PolarHBondContact O-N 2.75Å; S200-V228 WeakPolarHBondContact O-CG1 3.17Å
201K91.1Very high95.1Very high74 Ų7441 Ų4132%0.32222%0.219SC..THydrogen-bonded Turntrans-68-29.8174.7-63.1-179.7-179.7178.70111.4D199 K264D199-K201 PolarHBondContact O-N 3.4Å; D199-K201 VanDerWaalsContact O-N 3.16Å; D199-K201 VanDerWaalsContact OD1-CB 3.29Å; D199-K201 WeakPolarHBondContact OD1-CB 3.34Å; D199-K201 PolarHBondContact OD1-N 2.91Å; K201-K264 WeakPolarHBondContact O-CE 3.13Å; K201-K264 PolarHBondContact O-NZ 3.31Å
202W95Very high95.3Very high0 Ų040.3 Ų40.30%021%0.211CC..THydrogen-bonded Turntrans-87.9-55.5179.6-74.457000111.1T195 I196 D199 S200 L255 T258 W259 F262 K264 V371 K372T195-W202 HydrophobicContact CG2-CE3 3.9Å; T195-W202 HydrophobicContact CG2-CZ3 4.2Å; I196-W202 HydrophobicContact CB-CD2 4.34Å; I196-W202 HydrophobicContact CD1-CD2 4.16Å; I196-W202 VanDerWaalsContact CD1-CE2 3.49Å; I196-W202 HydrophobicContact CD1-CH2 4.21Å; I196-W202 HydrophobicContact CD1-CZ2 3.54Å; I196-W202 HydrophobicContact CG1-CD2 4.08Å; I196-W202 HydrophobicContact CG1-CE3 4.32Å; I196-W202 HydrophobicContact CG1-CH2 4.06Å; I196-W202 HydrophobicContact CG1-CZ2 3.88Å; I196-W202 HydrophobicContact CG1-CZ3 4.31Å; D199-W202 WeakPolarHBondContact O-CB 3.28Å; D199-W202 PolarHBondContact O-N 3.07Å; S200-W202 PolarHBondContact O-N 2.75Å; W202-L255 HydrophobicContact CZ2-CD2 4.43Å; W202-T258 HydrophobicContact CH2-CG2 3.83Å; W202-T258 HydrophobicContact CZ3-CG2 4.15Å; W202-W259 WeakPolarHBondContact CH2-O 3.36Å; W202-W259 HydrophobicContact CZ3-CB 4.41Å; W202-F262 HydrophobicContact CB-CE1 4.3Å; W202-F262 AromaticContact CD2-CD1 3.98Å; W202-F262 HydrophobicContact CD2-CD1 3.98Å; W202-F262 HydrophobicContact CD2-CE1 4.33Å; W202-F262 HydrophobicContact CE3-CB 4.26Å; W202-F262 AromaticContact CE3-CD1 3.41Å; W202-F262 HydrophobicContact CE3-CD1 3.41Å; W202-F262 VanDerWaalsContact CE3-CD1 3.41Å; W202-F262 AromaticContact CE3-CE1 3.96Å; W202-F262 HydrophobicContact CE3-CE1 3.96Å; W202-F262 AromaticContact CE3-CG 3.97Å; W202-F262 HydrophobicContact CE3-CG 3.97Å; W202-F262 HydrophobicContact CH2-CB 4.42Å; W202-F262 HydrophobicContact CZ3-CB 3.78Å; W202-F262 AromaticContact CZ3-CD1 3.83Å; W202-F262 HydrophobicContact CZ3-CD1 3.83Å; W202-F262 HydrophobicContact CZ3-CG 4Å; W202-K264 WeakPolarHBondContact O-CD 3.18Å; W202-K264 VanDerWaalsContact O-CE 3.28Å; W202-K264 WeakPolarHBondContact O-CE 3.49Å; W202-K264 PolarHBondContact O-NZ 3.37Å; W202-V371 HydrophobicContact CZ2-CG1 4.39Å; W202-K372 PolarHBondContact NE1-O 2.97Å
203L96.3Very high95.3Very high15 Ų1538 Ų388%0.07920%0.204CC..  trans-147.4125.7-177-67.1172.7000109.1T195 D199 P206 F208 F223 E225 F262T195-L203 HydrophobicContact CG2-CD1 4.15Å; D199-L203 PolarHBondContact O-N 2.9Å; L203-P206 HydrophobicContact CB-CG 4.04Å; L203-P206 HydrophobicContact CD1-CG 4.43Å; L203-P206 HydrophobicContact CD2-CB 4.23Å; L203-P206 HydrophobicContact CD2-CG 4.26Å; L203-P206 HydrophobicContact CG-CG 4.48Å; L203-F208 HydrophobicContact CD1-CZ 4.05Å; L203-F208 HydrophobicContact CD2-CE1 4.35Å; L203-F223 HydrophobicContact CD2-CE2 3.73Å; L203-F223 HydrophobicContact CD2-CZ 3.8Å; L203-E225 WeakPolarHBondContact CA-OE2 3.38Å; L203-F262 HydrophobicContact CD2-CZ 4.17Å; L203-F262 HydrophobicContact CG-CZ 4.5Å
204K94.5Very high95.1Very high79 Ų7938.7 Ų38.734%0.34321%0.209SC..SBendtrans-122.698.7176.5-172.7178.7173.2-178.90110.9E225 L226 V228K204-E225 PolarHBondContact N-OE2 3.05Å; K204-E225 VanDerWaalsContact N-OE2 3.1Å; K204-E225 WeakPolarHBondContact O-CB 3.13Å; K204-L226 HydrophobicContact CB-CB 4.45Å; K204-L226 HydrophobicContact CD-CB 3.9Å; K204-L226 HydrophobicContact CG-CB 3.98Å; K204-L226 HydrophobicContact CG-CD1 4.48Å; K204-L226 PolarHBondContact O-N 2.85Å; K204-V228 HydrophobicContact CB-CG1 3.98Å; K204-V228 HydrophobicContact CD-CG1 3.42Å; K204-V228 VanDerWaalsContact CD-CG1 3.42Å; K204-V228 HydrophobicContact CG-CG1 4.32Å
205E94.1Very high94.9Very high145 Ų14541 Ų4168%0.67824%0.235SC*.SBendtrans50.554.7-176.6-62.6176.1-157.600112.7L226E205-L226 HydrophobicContact CB-CD1 4.37Å; E205-L226 HydrophobicContact CB-CG 4.38Å; E205-L226 HydrophobicContact CG-CD1 4.46Å; E205-L226 WeakPolarHBondContact OE2-CD1 3.4Å
206P97Very high94.7Very high4 Ų443.1 Ų43.13%0.02625%0.246CC..  trans-71.2144.5-177.233.1-38.8000111.6R174 L203 F208 F223 R224 E225R174-P206 HydrophobicContact CB-CG 3.61Å; R174-P206 WeakPolarHBondContact CD-O 3.31Å; R174-P206 HydrophobicContact CG-CG 4.45Å; R174-P206 PolarHBondContact NH1-O 2.89Å; L203-P206 HydrophobicContact CB-CG 4.04Å; L203-P206 HydrophobicContact CD1-CG 4.43Å; L203-P206 HydrophobicContact CD2-CB 4.23Å; L203-P206 HydrophobicContact CD2-CG 4.26Å; L203-P206 HydrophobicContact CG-CG 4.48Å; P206-F208 HydrophobicContact CB-CD1 4.43Å; P206-F208 HydrophobicContact CB-CE1 3.94Å; P206-F208 HydrophobicContact CB-CE2 4.35Å; P206-F208 HydrophobicContact CB-CZ 3.91Å; P206-F208 HydrophobicContact CG-CE1 4.13Å; P206-F208 HydrophobicContact CG-CE2 3.89Å; P206-F208 HydrophobicContact CG-CZ 3.58Å; P206-F223 HydrophobicContact CB-CD2 3.79Å; P206-F223 HydrophobicContact CB-CE2 4.23Å; P206-R224 CarbonylContact C-O 3.57Å; P206-R224 WeakPolarHBondContact CA-O 3.49Å; P206-E225 HydrophobicContact CB-CB 4.27Å
207N97.1Very high94.8Very high35 Ų3542.7 Ų42.719%0.18725%0.251CS..EExtended strand (participates in β ladder)trans-113.5105.8166.7-174.5-30.9000107.9N144 I209 F223 R224N144-N207 WeakPolarHBondContact CB-OD1 3.44Å; N144-N207 VanDerWaalsContact CG-OD1 3.23Å; N144-N207 VanDerWaalsContact ND2-CG 3.35Å; N144-N207 PolarHBondContact ND2-ND2 3.4Å; N144-N207 PolarHBondContact ND2-OD1 3.39Å; N207-I209 WeakPolarHBondContact OD1-CD1 3.47Å; N207-F223 CarbonylContact O-C 3.47Å; N207-F223 VanDerWaalsContact O-CA 3.24Å; N207-F223 WeakPolarHBondContact O-CA 3.4Å; N207-F223 WeakPolarHBondContact O-CB 3.44Å; N207-R224 HydrophobicContact CB-CG 3.89Å; N207-R224 PolarHBondContact N-O 3.1Å; N207-R224 PolarHBondContact ND2-NH2 2.87Å; N207-R224 PolarHBondContact O-N 3.3Å
208F98.5Very high95.2Very high1 Ų138.7 Ų38.70%0.00423%0.231CC..EExtended strand (participates in β ladder)trans-82.8131.6-173.7-58.4-70.3000112T146 A164 R174 I176 L203 P206 F223T146-F208 HydrophobicContact CG2-CB 4.06Å; A164-F208 HydrophobicContact CB-CB 4.02Å; A164-F208 HydrophobicContact CB-CD1 3.47Å; A164-F208 VanDerWaalsContact CB-CD1 3.47Å; A164-F208 HydrophobicContact CB-CD2 3.78Å; A164-F208 HydrophobicContact CB-CE1 3.74Å; A164-F208 HydrophobicContact CB-CE2 3.97Å; A164-F208 HydrophobicContact CB-CG 3.5Å; A164-F208 VanDerWaalsContact CB-CG 3.5Å; A164-F208 HydrophobicContact CB-CZ 3.96Å; A164-F208 WeakPolarHBondContact O-CB 3.28Å; A164-F208 WeakPolarHBondContact O-CD2 3.43Å; R174-F208 HydrophobicContact CB-CE2 3.96Å; I176-F208 HydrophobicContact CD1-CE1 4.35Å; I176-F208 HydrophobicContact CG1-CE1 3.98Å; I176-F208 HydrophobicContact CG1-CZ 4.22Å; L203-F208 HydrophobicContact CD1-CZ 4.05Å; L203-F208 HydrophobicContact CD2-CE1 4.35Å; P206-F208 HydrophobicContact CB-CD1 4.43Å; P206-F208 HydrophobicContact CB-CE1 3.94Å; P206-F208 HydrophobicContact CB-CE2 4.35Å; P206-F208 HydrophobicContact CB-CZ 3.91Å; P206-F208 HydrophobicContact CG-CE1 4.13Å; P206-F208 HydrophobicContact CG-CE2 3.89Å; P206-F208 HydrophobicContact CG-CZ 3.58Å; F208-F223 HydrophobicContact CD1-CB 3.7Å; F208-F223 HydrophobicContact CD1-CD1 4.34Å; F208-F223 HydrophobicContact CD1-CG 4.01Å; F208-F223 HydrophobicContact CE1-CB 4.42Å; F208-F223 HydrophobicContact CE1-CG 4.28Å; F208-F223 HydrophobicContact CG-CB 4.43Å
209I98.2Very high95.8Very high20 Ų2034.8 Ų34.810%0.10320%0.199CC..EExtended strand (participates in β ladder)trans-113.8-51-168.7-57.4-54.3000111.8N207 F222 R224 I282 Q283N207-I209 WeakPolarHBondContact OD1-CD1 3.47Å; I209-F222 WeakPolarHBondContact CB-O 3.29Å; I209-F222 PolarHBondContact N-O 2.75Å; I209-R224 VanDerWaalsContact CD1-NH1 3.3Å; I209-I282 HydrophobicContact CG1-CG2 4.04Å; I209-Q283 VanDerWaalsContact CG2-O 3.31Å; I209-Q283 WeakPolarHBondContact CG2-O 3.29Å
210A98.1Very high96.1Very high8 Ų833.2 Ų33.27%0.06619%0.191CC..EExtended strand (participates in β ladder)trans-149.1154.8-177.300000112.1T146 F212 F221 F222 V285T146-A210 WeakPolarHBondContact OG1-CA 3.41Å; A210-F212 HydrophobicContact CB-CE2 3.58Å; A210-F212 HydrophobicContact CB-CZ 3.79Å; A210-F221 WeakPolarHBondContact O-CA 3.28Å; A210-F222 HydrophobicContact CB-CB 4.32Å; A210-F222 PolarHBondContact N-O 3.06Å; A210-F222 PolarHBondContact O-N 3.27Å; A210-V285 HydrophobicContact CB-CB 3.87Å; A210-V285 HydrophobicContact CB-CG2 4.24Å
211S98.5Very high96.5Very high10 Ų1030.4 Ų30.47%0.0717%0.171CC..EExtended strand (participates in β ladder)trans-140.6142.5174.8550000110.6T146 A147 Y220T146-S211 PolarHBondContact OG1-N 3.35Å; T146-S211 PolarHBondContact OG1-OG 2.81Å; A147-S211 PolarHBondContact N-OG 3.48Å; A147-S211 PolarHBondContact O-OG 3.22Å; S211-Y220 CarbonylContact C-O 3.57Å; S211-Y220 WeakPolarHBondContact CA-O 3.13Å
212F98.1Very high96.8Very high31 Ų3126.9 Ų26.914%0.13616%0.155CC..EExtended strand (participates in β ladder)trans-140.6137.1-173.6-58-77.1000111.9A210 V214 Y220 F222 V285 M287 F297A210-F212 HydrophobicContact CB-CE2 3.58Å; A210-F212 HydrophobicContact CB-CZ 3.79Å; F212-V214 HydrophobicContact CB-CG1 4.34Å; F212-Y220 PolarHBondContact N-O 3.19Å; F212-Y220 PolarHBondContact O-N 2.78Å; F212-F222 AromaticContact CD2-CD2 3.84Å; F212-F222 HydrophobicContact CD2-CD2 3.84Å; F212-F222 AromaticContact CD2-CE2 3.66Å; F212-F222 HydrophobicContact CD2-CE2 3.66Å; F212-F222 AromaticContact CE2-CD2 3.83Å; F212-F222 HydrophobicContact CE2-CD2 3.83Å; F212-F222 AromaticContact CE2-CE2 3.89Å; F212-F222 HydrophobicContact CE2-CE2 3.89Å; F212-V285 HydrophobicContact CE2-CB 4.07Å; F212-V285 HydrophobicContact CE2-CG1 3.78Å; F212-V285 HydrophobicContact CZ-CB 4.25Å; F212-V285 HydrophobicContact CZ-CG1 4.13Å; F212-V285 WeakPolarHBondContact CZ-O 3.26Å; F212-M287 HydrophobicContact CB-SD 4.15Å; F212-M287 HydrophobicContact CD1-CB 3.72Å; F212-M287 HydrophobicContact CD1-CE 4.11Å; F212-M287 HydrophobicContact CD1-CG 4.4Å; F212-M287 HydrophobicContact CD1-SD 3.94Å; F212-M287 HydrophobicContact CE1-CB 3.54Å; F212-M287 HydrophobicContact CG-CB 4.36Å; F212-M287 HydrophobicContact CG-SD 4.18Å; F212-M287 HydrophobicContact CZ-CB 4.03Å; F212-F297 HydrophobicContact CB-CE1 4.38Å; F212-F297 HydrophobicContact CD2-CD1 4.14Å; F212-F297 AromaticContact CD2-CE1 3.68Å; F212-F297 HydrophobicContact CD2-CE1 3.68Å; F212-F297 HydrophobicContact CE2-CD1 4.1Å; F212-F297 HydrophobicContact CE2-CE1 4.1Å; F212-F297 HydrophobicContact CG-CE1 4.02Å
213D96.9Very high97Very high40 Ų4026.9 Ų26.921%0.21416%0.155CC..EExtended strand (participates in β ladder)trans-97.6110.9160.5-177.9-2.6000108.7V148 V150 G215 K246V148-D213 HydrophobicContact CG2-CB 4.14Å; V150-D213 HydrophobicContact CG2-CB 4.24Å; D213-G215 PolarHBondContact OD1-N 3.24Å; D213-K246 VanDerWaalsContact OD1-CE 3.31Å; D213-K246 WeakPolarHBondContact OD1-CE 3.44Å; D213-K246 IonicContact OD1-NZ 3.76Å; D213-K246 PolarHBondContact OD1-NZ 2.81Å; D213-K246 IonicContact OD2-NZ 3.38Å; D213-K246 PolarHBondContact OD2-NZ 2.84Å
214V94.4Very high97.1Very high16 Ų1627.7 Ų27.710%0.09716%0.157CC..  trans-95.1-3180-56.30000113.2F212 D216 Y220 M287 T295 F297 L318F212-V214 HydrophobicContact CB-CG1 4.34Å; V214-D216 HydrophobicContact CG2-CB 4.13Å; V214-D216 VanDerWaalsContact CG2-CG 3.44Å; V214-D216 VanDerWaalsContact CG2-OD1 3.26Å; V214-D216 WeakPolarHBondContact CG2-OD1 3.48Å; V214-Y220 HydrophobicContact CG1-CD2 4.18Å; V214-Y220 HydrophobicContact CG1-CE2 4.48Å; V214-Y220 HydrophobicContact CG2-CD2 3.85Å; V214-Y220 HydrophobicContact CG2-CE2 3.41Å; V214-Y220 VanDerWaalsContact CG2-CE2 3.41Å; V214-M287 HydrophobicContact CG1-SD 3.98Å; V214-T295 HydrophobicContact CG1-CG2 4.43Å; V214-F297 HydrophobicContact CG1-CZ 3.98Å; V214-L318 HydrophobicContact CB-CD2 3.9Å; V214-L318 HydrophobicContact CG1-CD1 4.48Å; V214-L318 HydrophobicContact CG1-CD2 4.21Å; V214-L318 HydrophobicContact CG2-CD1 4.25Å; V214-L318 HydrophobicContact CG2-CD2 3.76Å
215G92.6Very high97.2Very high63 Ų6324 Ų2465%0.64914%0.142SC*.SBendtrans85.18.8177.900000115.9D213D213-G215 PolarHBondContact OD1-N 3.24Å
216D94.6Very high97.2Very high43 Ų4318.8 Ų18.823%0.2312%0.118CC..SBendtrans-96.512.7-17871.9-12.5000114.1V214 Y218 Y220V214-D216 HydrophobicContact CG2-CB 4.13Å; V214-D216 VanDerWaalsContact CG2-CG 3.44Å; V214-D216 VanDerWaalsContact CG2-OD1 3.26Å; V214-D216 WeakPolarHBondContact CG2-OD1 3.48Å; D216-Y218 VanDerWaalsContact C-N 3.34Å; D216-Y218 WeakPolarHBondContact O-CD2 3.42Å; D216-Y218 WeakPolarHBondContact OD1-CB 3.43Å; D216-Y218 PolarHBondContact OD1-N 2.84Å; D216-Y220 PolarHBondContact OD2-OH 3.08Å
217G96.5Very high97Very high26 Ų2619 Ų1927%0.26812%0.121SC..SBendtrans87.6-3.1-175.600000114.5K246G217-K246 WeakPolarHBondContact O-CB 3.28Å; G217-K246 VanDerWaalsContact O-CG 3.29Å; G217-K246 WeakPolarHBondContact O-CG 3.33Å; G217-K246 PolarHBondContact O-N 2.85Å
218Y98.3Very high96.6Very high28 Ų2818.5 Ų18.511%0.1112%0.119CC..EExtended strand (participates in β ladder)trans-113.1160.5176.1-59.2-88.9000112.3D216 R243 I244 C245 K246 C356D216-Y218 VanDerWaalsContact C-N 3.34Å; D216-Y218 WeakPolarHBondContact O-CD2 3.42Å; D216-Y218 WeakPolarHBondContact OD1-CB 3.43Å; D216-Y218 PolarHBondContact OD1-N 2.84Å; Y218-R243 HydrophobicContact CD1-CG 4.37Å; Y218-I244 CarbonylContact C-O 3.59Å; Y218-I244 WeakPolarHBondContact CA-O 3.29Å; Y218-I244 WeakPolarHBondContact CB-O 3.4Å; Y218-I244 WeakPolarHBondContact CD1-O 3.36Å; Y218-C245 HydrophobicContact CD1-CB 4.17Å; Y218-C245 HydrophobicContact CE1-CB 4.01Å; Y218-K246 VanDerWaalsContact O-CE 3.3Å; Y218-K246 WeakPolarHBondContact O-CE 3.35Å; Y218-C356 VanDerWaalsContact CE1-SG 3.59Å; Y218-C356 VanDerWaalsContact CZ-SG 3.54Å; Y218-C356 PolarHBondContact OH-N 2.96Å; Y218-C356 VanDerWaalsContact OH-N 3.14Å
219V98.6Very high96.1Very high0 Ų019.7 Ų19.70%012%0.124CC..EExtended strand (participates in β ladder)trans-115.2130.4165.5-174.20000107.8V148 V150 Y162 F221 R243 I244 K246V148-V219 HydrophobicContact CG1-CG1 3.63Å; V150-V219 HydrophobicContact CG2-CG2 3.83Å; Y162-V219 HydrophobicContact CD1-CG2 4.18Å; Y162-V219 HydrophobicContact CD2-CG2 4.26Å; Y162-V219 HydrophobicContact CE1-CG2 4.25Å; Y162-V219 HydrophobicContact CE2-CG2 4.36Å; Y162-V219 HydrophobicContact CG-CG2 4.15Å; V219-F221 HydrophobicContact CB-CE2 4.03Å; V219-F221 HydrophobicContact CG1-CD2 4.38Å; V219-F221 HydrophobicContact CG1-CE2 3.58Å; V219-F221 HydrophobicContact CG1-CZ 3.71Å; V219-R243 WeakPolarHBondContact O-CA 3.24Å; V219-I244 HydrophobicContact CB-CD1 4.32Å; V219-I244 HydrophobicContact CB-CG1 3.92Å; V219-I244 PolarHBondContact N-O 3.1Å; V219-I244 PolarHBondContact O-N 2.78Å; V219-K246 HydrophobicContact CG2-CG 3.85Å
220Y98.7Very high95.3Very high0 Ų023.3 Ų23.30%014%0.138CC..EExtended strand (participates in β ladder)trans-104.4141.6-178.2-65.5-95.1000110.6S211 F212 V214 D216 V241 A242 R243 L318 I321 K322 F325S211-Y220 CarbonylContact C-O 3.57Å; S211-Y220 WeakPolarHBondContact CA-O 3.13Å; F212-Y220 PolarHBondContact N-O 3.19Å; F212-Y220 PolarHBondContact O-N 2.78Å; V214-Y220 HydrophobicContact CG1-CD2 4.18Å; V214-Y220 HydrophobicContact CG1-CE2 4.48Å; V214-Y220 HydrophobicContact CG2-CD2 3.85Å; V214-Y220 HydrophobicContact CG2-CE2 3.41Å; V214-Y220 VanDerWaalsContact CG2-CE2 3.41Å; D216-Y220 PolarHBondContact OD2-OH 3.08Å; Y220-V241 HydrophobicContact CD1-CG1 4.21Å; Y220-A242 CarbonylContact C-O 3.38Å; Y220-A242 VanDerWaalsContact CA-O 3.3Å; Y220-A242 WeakPolarHBondContact CA-O 3.38Å; Y220-R243 HydrophobicContact CD1-CB 3.9Å; Y220-R243 HydrophobicContact CE1-CB 3.87Å; Y220-L318 HydrophobicContact CE1-CD1 4.19Å; Y220-L318 HydrophobicContact CE2-CD1 4.05Å; Y220-I321 HydrophobicContact CD1-CG2 4.19Å; Y220-I321 HydrophobicContact CE1-CG2 3.88Å; Y220-K322 WeakPolarHBondContact OH-CG 3.41Å; Y220-F325 HydrophobicContact CE1-CE2 4.36Å
221F98.8Very high93.7Very high0 Ų027 Ų270%017%0.168CC..EExtended strand (participates in β ladder)trans-128.2131.3178.1-64.2-92.9000110.3T146 A164 I176 A210 V219 F223 V241 A242 I244T146-F221 HydrophobicContact CG2-CD1 4.27Å; A164-F221 HydrophobicContact CB-CD1 3.61Å; A164-F221 HydrophobicContact CB-CE1 3.79Å; I176-F221 HydrophobicContact CD1-CB 4.29Å; I176-F221 HydrophobicContact CD1-CD1 4.5Å; I176-F221 HydrophobicContact CD1-CD2 4.05Å; I176-F221 HydrophobicContact CD1-CG 4.02Å; I176-F221 HydrophobicContact CG1-CD1 4.33Å; I176-F221 HydrophobicContact CG1-CE1 4.49Å; I176-F221 HydrophobicContact CG1-CG 4.34Å; I176-F221 HydrophobicContact CG2-CD2 4.18Å; I176-F221 HydrophobicContact CG2-CE1 3.95Å; I176-F221 HydrophobicContact CG2-CE2 3.58Å; I176-F221 HydrophobicContact CG2-CZ 3.43Å; I176-F221 VanDerWaalsContact CG2-CZ 3.43Å; A210-F221 WeakPolarHBondContact O-CA 3.28Å; V219-F221 HydrophobicContact CB-CE2 4.03Å; V219-F221 HydrophobicContact CG1-CD2 4.38Å; V219-F221 HydrophobicContact CG1-CE2 3.58Å; V219-F221 HydrophobicContact CG1-CZ 3.71Å; F221-F223 HydrophobicContact CB-CD1 4.48Å; F221-V241 CarbonylContact O-C 3.6Å; F221-V241 WeakPolarHBondContact O-CA 3.38Å; F221-A242 PolarHBondContact N-O 3.12Å; F221-A242 PolarHBondContact O-N 3.2Å; F221-I244 HydrophobicContact CE2-CD1 3.65Å; F221-I244 HydrophobicContact CE2-CG1 3.93Å; F221-I244 HydrophobicContact CZ-CD1 4.21Å
222F98.9Very high92Very high0 Ų029.8 Ų29.80%019%0.187CC..EExtended strand (participates in β ladder)trans-110129.2176.1-67.4-103.5000108.8I209 A210 F212 R240 V241 I267 I282 V285 F297 I321I209-F222 WeakPolarHBondContact CB-O 3.29Å; I209-F222 PolarHBondContact N-O 2.75Å; A210-F222 HydrophobicContact CB-CB 4.32Å; A210-F222 PolarHBondContact N-O 3.06Å; A210-F222 PolarHBondContact O-N 3.27Å; F212-F222 AromaticContact CD2-CD2 3.84Å; F212-F222 HydrophobicContact CD2-CD2 3.84Å; F212-F222 AromaticContact CD2-CE2 3.66Å; F212-F222 HydrophobicContact CD2-CE2 3.66Å; F212-F222 AromaticContact CE2-CD2 3.83Å; F212-F222 HydrophobicContact CE2-CD2 3.83Å; F212-F222 AromaticContact CE2-CE2 3.89Å; F212-F222 HydrophobicContact CE2-CE2 3.89Å; F222-R240 WeakPolarHBondContact CA-O 3.36Å; F222-V241 HydrophobicContact CD1-CG2 3.56Å; F222-V241 HydrophobicContact CE1-CB 4.47Å; F222-V241 HydrophobicContact CE1-CG1 4.34Å; F222-V241 HydrophobicContact CE1-CG2 3.35Å; F222-V241 HydrophobicContact CE2-CG1 4.45Å; F222-V241 HydrophobicContact CG-CG2 4.38Å; F222-V241 HydrophobicContact CZ-CG1 4.2Å; F222-V241 HydrophobicContact CZ-CG2 4.01Å; F222-I267 HydrophobicContact CD1-CD1 4.49Å; F222-I267 HydrophobicContact CE1-CD1 4.08Å; F222-I282 HydrophobicContact CB-CD1 4.37Å; F222-I282 HydrophobicContact CD1-CD1 4.12Å; F222-V285 HydrophobicContact CB-CG2 3.74Å; F222-V285 HydrophobicContact CD1-CG1 4.22Å; F222-V285 HydrophobicContact CD1-CG2 3.79Å; F222-V285 HydrophobicContact CD2-CG1 4.45Å; F222-V285 HydrophobicContact CE1-CG1 4.23Å; F222-V285 HydrophobicContact CE2-CG1 4.48Å; F222-V285 HydrophobicContact CG-CB 4.42Å; F222-V285 HydrophobicContact CG-CG1 4.33Å; F222-V285 HydrophobicContact CG-CG2 3.79Å; F222-V285 HydrophobicContact CZ-CG1 4.37Å; F222-F297 HydrophobicContact CE1-CB 4.43Å; F222-F297 HydrophobicContact CE1-CG 4.38Å; F222-F297 AromaticContact CE2-CD1 3.93Å; F222-F297 HydrophobicContact CE2-CD1 3.93Å; F222-F297 AromaticContact CE2-CE1 3.92Å; F222-F297 HydrophobicContact CE2-CE1 3.92Å; F222-F297 HydrophobicContact CE2-CG 4.42Å; F222-F297 HydrophobicContact CE2-CZ 4.4Å; F222-F297 HydrophobicContact CZ-CB 4.22Å; F222-F297 AromaticContact CZ-CD1 3.67Å; F222-F297 HydrophobicContact CZ-CD1 3.67Å; F222-F297 HydrophobicContact CZ-CD2 4.05Å; F222-F297 AromaticContact CZ-CE1 3.97Å; F222-F297 HydrophobicContact CZ-CE1 3.97Å; F222-F297 HydrophobicContact CZ-CE2 4.32Å; F222-F297 AromaticContact CZ-CG 3.7Å; F222-F297 HydrophobicContact CZ-CG 3.7Å; F222-F297 HydrophobicContact CZ-CZ 4.27Å; F222-I321 HydrophobicContact CZ-CD1 4.27Å
223F98.7Very high90.4Very high0 Ų034.8 Ų34.80%023%0.225CC..EExtended strand (participates in β ladder)trans-158.1169.5-175.762.6-80.5000110.9L203 P206 N207 F208 F221 E225 S239 R240 A242 K264L203-F223 HydrophobicContact CD2-CE2 3.73Å; L203-F223 HydrophobicContact CD2-CZ 3.8Å; P206-F223 HydrophobicContact CB-CD2 3.79Å; P206-F223 HydrophobicContact CB-CE2 4.23Å; N207-F223 CarbonylContact O-C 3.47Å; N207-F223 VanDerWaalsContact O-CA 3.24Å; N207-F223 WeakPolarHBondContact O-CA 3.4Å; N207-F223 WeakPolarHBondContact O-CB 3.44Å; F208-F223 HydrophobicContact CD1-CB 3.7Å; F208-F223 HydrophobicContact CD1-CD1 4.34Å; F208-F223 HydrophobicContact CD1-CG 4.01Å; F208-F223 HydrophobicContact CE1-CB 4.42Å; F208-F223 HydrophobicContact CE1-CG 4.28Å; F208-F223 HydrophobicContact CG-CB 4.43Å; F221-F223 HydrophobicContact CB-CD1 4.48Å; F223-E225 HydrophobicContact CD2-CB 4.21Å; F223-E225 HydrophobicContact CD2-CG 4.47Å; F223-E225 HydrophobicContact CE2-CB 4.18Å; F223-E225 HydrophobicContact CE2-CG 4.08Å; F223-S239 CarbonylContact O-C 3.55Å; F223-S239 WeakPolarHBondContact O-CA 3.29Å; F223-R240 HydrophobicContact CD1-CB 3.95Å; F223-R240 HydrophobicContact CD2-CB 3.98Å; F223-R240 HydrophobicContact CD2-CG 4.16Å; F223-R240 HydrophobicContact CE1-CB 3.61Å; F223-R240 HydrophobicContact CE1-CG 4.47Å; F223-R240 HydrophobicContact CE2-CB 3.67Å; F223-R240 HydrophobicContact CE2-CG 3.67Å; F223-R240 HydrophobicContact CG-CB 4.11Å; F223-R240 HydrophobicContact CZ-CB 3.47Å; F223-R240 VanDerWaalsContact CZ-CB 3.47Å; F223-R240 HydrophobicContact CZ-CG 3.85Å; F223-R240 PolarHBondContact N-O 3.28Å; F223-R240 VanDerWaalsContact N-O 3.13Å; F223-R240 PolarHBondContact O-N 2.03Å; F223-A242 HydrophobicContact CE1-CB 3.68Å; F223-A242 HydrophobicContact CZ-CB 4.34Å; F223-K264 HydrophobicContact CZ-CB 4.4Å; F223-K264 HydrophobicContact CZ-CD 4.26Å
224R97.8Very high89.3Confident32 Ų3238.5 Ų38.512%0.12125%0.245CC..EExtended strand (participates in β ladder)trans-120.9147.6166.260.5-174.3-175.5-97.45.9109.8P206 N207 I209 V237 Y238 E281 I282P206-R224 CarbonylContact C-O 3.57Å; P206-R224 WeakPolarHBondContact CA-O 3.49Å; N207-R224 HydrophobicContact CB-CG 3.89Å; N207-R224 PolarHBondContact N-O 3.1Å; N207-R224 PolarHBondContact ND2-NH2 2.87Å; N207-R224 PolarHBondContact O-N 3.3Å; I209-R224 VanDerWaalsContact CD1-NH1 3.3Å; R224-V237 HydrophobicContact CB-CG1 3.83Å; R224-V237 HydrophobicContact CG-CG1 4.21Å; R224-Y238 CarbonylContact C-O 3.47Å; R224-Y238 VanDerWaalsContact CA-O 3.27Å; R224-Y238 WeakPolarHBondContact CA-O 3.49Å; R224-E281 IonicContact NE-OE2 3.98Å; R224-I282 HydrophobicContact CB-CG2 4.18Å; R224-I282 PolarHBondContact NH1-O 2.53Å
225E96.5Very high88.6Confident3 Ų341.9 Ų41.91%0.01427%0.274CS..EExtended strand (participates in β ladder)trans-148.4171.9-178.769.2173.2170.400110.2L203 K204 P206 F223 G227 V237 Y238 R240 K264L203-E225 WeakPolarHBondContact CA-OE2 3.38Å; K204-E225 PolarHBondContact N-OE2 3.05Å; K204-E225 VanDerWaalsContact N-OE2 3.1Å; K204-E225 WeakPolarHBondContact O-CB 3.13Å; P206-E225 HydrophobicContact CB-CB 4.27Å; F223-E225 HydrophobicContact CD2-CB 4.21Å; F223-E225 HydrophobicContact CD2-CG 4.47Å; F223-E225 HydrophobicContact CE2-CB 4.18Å; F223-E225 HydrophobicContact CE2-CG 4.08Å; E225-G227 PolarHBondContact O-N 3.12Å; E225-V237 CarbonylContact O-C 3.42Å; E225-V237 WeakPolarHBondContact O-CA 3.06Å; E225-Y238 PolarHBondContact N-O 3.32Å; E225-Y238 PolarHBondContact O-N 3.42Å; E225-R240 HydrophobicContact CG-CG 3.93Å; E225-R240 IonicContact OE1-CZ 3.77Å; E225-R240 IonicContact OE1-NE 2.72Å; E225-R240 PolarHBondContact OE1-NE 2.89Å; E225-R240 IonicContact OE1-NH2 3.98Å; E225-R240 PolarHBondContact OE1-NH2 3.36Å; E225-K264 VanDerWaalsContact CD-NZ 3.26Å; E225-K264 WeakPolarHBondContact OE1-CD 3.46Å; E225-K264 WeakPolarHBondContact OE1-CE 3.1Å; E225-K264 IonicContact OE1-NZ 3.74Å; E225-K264 PolarHBondContact OE1-NZ 3.41Å; E225-K264 IonicContact OE2-NZ 2.62Å; E225-K264 PolarHBondContact OE2-NZ 3.4Å
226L94.4Very high88.4Confident35 Ų3539.7 Ų39.718%0.18325%0.25CC..EExtended strand (participates in β ladder)trans-70.1122.5168.6-61.9-177.4000110K204 E205 V228 A235 V237K204-L226 HydrophobicContact CB-CB 4.45Å; K204-L226 HydrophobicContact CD-CB 3.9Å; K204-L226 HydrophobicContact CG-CB 3.98Å; K204-L226 HydrophobicContact CG-CD1 4.48Å; K204-L226 PolarHBondContact O-N 2.85Å; E205-L226 HydrophobicContact CB-CD1 4.37Å; E205-L226 HydrophobicContact CB-CG 4.38Å; E205-L226 HydrophobicContact CG-CD1 4.46Å; E205-L226 WeakPolarHBondContact OE2-CD1 3.4Å; L226-V228 PolarHBondContact O-N 3.32Å; L226-A235 HydrophobicContact CD2-CB 4.32Å; L226-V237 HydrophobicContact CD2-CG2 4.16Å
227G92.5Very high88.4Confident8 Ų839.6 Ų39.68%0.08225%0.251CS..  trans-69.298.3179.600000111.9E225 E229 Y230 A236E225-G227 PolarHBondContact O-N 3.12Å; G227-E229 WeakPolarHBondContact CA-OE2 3.43Å; G227-E229 PolarHBondContact O-N 3.09Å; G227-Y230 WeakPolarHBondContact O-CB 3.34Å; G227-Y230 PolarHBondContact O-N 3.12Å; G227-Y230 VanDerWaalsContact O-N 3.09Å; G227-A236 PolarHBondContact N-O 2.79Å
228V88.8Confident88.4Confident24 Ų2439.6 Ų39.615%0.14524%0.243CC..THydrogen-bonded Turntrans-60.3-24.2175.4-700000113.5S200 K204 L226 Y230 W340S200-V228 WeakPolarHBondContact O-CG1 3.17Å; K204-V228 HydrophobicContact CB-CG1 3.98Å; K204-V228 HydrophobicContact CD-CG1 3.42Å; K204-V228 VanDerWaalsContact CD-CG1 3.42Å; K204-V228 HydrophobicContact CG-CG1 4.32Å; L226-V228 PolarHBondContact O-N 3.32Å; V228-Y230 VanDerWaalsContact C-N 3.32Å; V228-W340 HydrophobicContact CB-CZ2 3.91Å; V228-W340 HydrophobicContact CG2-CH2 3.9Å; V228-W340 HydrophobicContact CG2-CZ2 3.47Å; V228-W340 VanDerWaalsContact CG2-CZ2 3.47Å; V228-W340 PolarHBondContact O-NE1 3.14Å
229E89Confident88.4Confident26 Ų2638.3 Ų38.312%0.12124%0.238CC..THydrogen-bonded Turntrans-81.7-8.7177.975.8-85.1-146.300114.5G227 A231 Y238 R240 W340 L376G227-E229 WeakPolarHBondContact CA-OE2 3.43Å; G227-E229 PolarHBondContact O-N 3.09Å; E229-A231 PolarHBondContact O-N 2.64Å; E229-Y238 HydrophobicContact CG-CE2 4.04Å; E229-Y238 VanDerWaalsContact OE1-CD2 3.26Å; E229-Y238 WeakPolarHBondContact OE1-CD2 3.32Å; E229-R240 IonicContact OE1-CZ 2.77Å; E229-R240 IonicContact OE1-NH1 3.98Å; E229-R240 PolarHBondContact OE1-NH1 3.16Å; E229-R240 IonicContact OE1-NH2 2.78Å; E229-R240 PolarHBondContact OE1-NH2 3.12Å; E229-R240 IonicContact OE2-CZ 3.95Å; E229-R240 IonicContact OE2-NH1 3.71Å; E229-R240 IonicContact OE2-NH2 2.79Å; E229-R240 PolarHBondContact OE2-NH2 3.31Å; E229-W340 HydrophobicContact CB-CB 3.99Å; E229-W340 HydrophobicContact CB-CD2 3.97Å; E229-W340 HydrophobicContact CB-CG 3.69Å; E229-L376 HydrophobicContact CB-CD2 4.11Å; E229-L376 HydrophobicContact CG-CD2 4.29Å
230Y79.6Confident88.4Confident97 Ų9738.3 Ų38.338%0.3824%0.238SC..  trans-78.5103.6175.3-167.2-108.8000109.1G227 V228 S232 D234 A236 Y238G227-Y230 WeakPolarHBondContact O-CB 3.34Å; G227-Y230 PolarHBondContact O-N 3.12Å; G227-Y230 VanDerWaalsContact O-N 3.09Å; V228-Y230 VanDerWaalsContact C-N 3.32Å; Y230-S232 VanDerWaalsContact C-N 3.27Å; Y230-S232 PolarHBondContact O-N 3.21Å; Y230-D234 WeakPolarHBondContact CD1-O 3.25Å; Y230-D234 VanDerWaalsContact CE1-O 3.23Å; Y230-D234 WeakPolarHBondContact CE1-O 3.32Å; Y230-A236 HydrophobicContact CD1-CB 3.6Å; Y230-A236 HydrophobicContact CD2-CB 4.04Å; Y230-A236 HydrophobicContact CE1-CB 3.94Å; Y230-A236 HydrophobicContact CE2-CB 4.38Å; Y230-A236 HydrophobicContact CG-CB 3.63Å; Y230-Y238 WeakPolarHBondContact CD2-OH 3.4Å
231A65Low88.4Confident85 Ų8538.3 Ų38.370%0.70224%0.238SC*.  trans-81.33.3-171.600000114.7E229E229-A231 PolarHBondContact O-N 2.64Å
232S63.7Low88.4Confident68 Ų6838.3 Ų38.348%0.47624%0.238SC..SBendtrans-80.9167.4177.7-162.40000111.5Y230 D234Y230-S232 VanDerWaalsContact C-N 3.27Å; Y230-S232 PolarHBondContact O-N 3.21Å; S232-D234 PolarHBondContact O-N 2.02Å
233C64.4Low88.3Confident137 Ų13738.4 Ų38.493%0.92624%0.238SC*.SBendtrans-64.1-25.6176.3-63.30000113.2
234D72.6Confident88.3Confident118 Ų11838.4 Ų38.463%0.63124%0.238SC*.SBendtrans-87.8144.2-179.2-64.3-36.2000112.2Y230 S232Y230-D234 WeakPolarHBondContact CD1-O 3.25Å; Y230-D234 VanDerWaalsContact CE1-O 3.23Å; Y230-D234 WeakPolarHBondContact CE1-O 3.32Å; S232-D234 PolarHBondContact O-N 2.02Å
235A81.2Confident88.3Confident86 Ų8637 Ų3771%0.71123%0.233SC*.  trans-75.5127.3172.100000110.6L226L226-A235 HydrophobicContact CD2-CB 4.32Å
236A88.9Confident88.4Confident18 Ų1837.2 Ų37.215%0.14923%0.234CC..  trans-108.2135.8171.200000110.3G227 Y230 Y238G227-A236 PolarHBondContact N-O 2.79Å; Y230-A236 HydrophobicContact CD1-CB 3.6Å; Y230-A236 HydrophobicContact CD2-CB 4.04Å; Y230-A236 HydrophobicContact CE1-CB 3.94Å; Y230-A236 HydrophobicContact CE2-CB 4.38Å; Y230-A236 HydrophobicContact CG-CB 3.63Å; A236-Y238 HydrophobicContact CB-CE1 4.49Å
237V94.3Very high88.5Confident41 Ų4137.7 Ų37.725%0.24824%0.24CC..EExtended strand (participates in β ladder)trans-83137.8168.7178.50000108.5R224 E225 L226 N280 E281R224-V237 HydrophobicContact CB-CG1 3.83Å; R224-V237 HydrophobicContact CG-CG1 4.21Å; E225-V237 CarbonylContact O-C 3.42Å; E225-V237 WeakPolarHBondContact O-CA 3.06Å; L226-V237 HydrophobicContact CD2-CG2 4.16Å; V237-N280 VanDerWaalsContact O-CB 3.26Å; V237-N280 WeakPolarHBondContact O-CB 3.33Å; V237-E281 HydrophobicContact CB-CG 4.28Å; V237-E281 HydrophobicContact CG1-CG 3.93Å
238Y96.2Very high88.7Confident26 Ų2637.5 Ų37.510%0.10224%0.238CC..EExtended strand (participates in β ladder)trans-127.4137.3170.3-72.8-33000111.6R224 E225 E229 Y230 A236R224-Y238 CarbonylContact C-O 3.47Å; R224-Y238 VanDerWaalsContact CA-O 3.27Å; R224-Y238 WeakPolarHBondContact CA-O 3.49Å; E225-Y238 PolarHBondContact N-O 3.32Å; E225-Y238 PolarHBondContact O-N 3.42Å; E229-Y238 HydrophobicContact CG-CE2 4.04Å; E229-Y238 VanDerWaalsContact OE1-CD2 3.26Å; E229-Y238 WeakPolarHBondContact OE1-CD2 3.32Å; Y230-Y238 WeakPolarHBondContact CD2-OH 3.4Å; A236-Y238 HydrophobicContact CB-CE1 4.49Å
239S98.4Very high89.1Confident1 Ų137 Ų371%0.00723%0.234CC..EExtended strand (participates in β ladder)trans-74.8141.5167.5-65.70000110.9F223 R266 I267 N280 I282F223-S239 CarbonylContact O-C 3.55Å; F223-S239 WeakPolarHBondContact O-CA 3.29Å; S239-R266 WeakPolarHBondContact O-CA 3.09Å; S239-I267 PolarHBondContact O-N 2.89Å; S239-N280 PolarHBondContact N-O 2.63Å; S239-N280 VanDerWaalsContact N-O 3.12Å; S239-N280 PolarHBondContact OG-O 3.2Å; S239-I282 VanDerWaalsContact OG-CB 3.27Å; S239-I282 WeakPolarHBondContact OG-CB 3.26Å; S239-I282 WeakPolarHBondContact OG-CG2 3.11Å; S239-I282 PolarHBondContact OG-N 2.91Å
240R98.4Very high89.4Confident0 Ų035.8 Ų35.80%023%0.229CC..EExtended strand (participates in β ladder)trans-131.7150.1-173.5-60-61.1-165.1-162.9-6.3111.9F222 F223 E225 E229 T265F222-R240 WeakPolarHBondContact CA-O 3.36Å; F223-R240 HydrophobicContact CD1-CB 3.95Å; F223-R240 HydrophobicContact CD2-CB 3.98Å; F223-R240 HydrophobicContact CD2-CG 4.16Å; F223-R240 HydrophobicContact CE1-CB 3.61Å; F223-R240 HydrophobicContact CE1-CG 4.47Å; F223-R240 HydrophobicContact CE2-CB 3.67Å; F223-R240 HydrophobicContact CE2-CG 3.67Å; F223-R240 HydrophobicContact CG-CB 4.11Å; F223-R240 HydrophobicContact CZ-CB 3.47Å; F223-R240 VanDerWaalsContact CZ-CB 3.47Å; F223-R240 HydrophobicContact CZ-CG 3.85Å; F223-R240 PolarHBondContact N-O 3.28Å; F223-R240 VanDerWaalsContact N-O 3.13Å; F223-R240 PolarHBondContact O-N 2.03Å; E225-R240 HydrophobicContact CG-CG 3.93Å; E225-R240 IonicContact OE1-CZ 3.77Å; E225-R240 IonicContact OE1-NE 2.72Å; E225-R240 PolarHBondContact OE1-NE 2.89Å; E225-R240 IonicContact OE1-NH2 3.98Å; E225-R240 PolarHBondContact OE1-NH2 3.36Å; E229-R240 IonicContact OE1-CZ 2.77Å; E229-R240 IonicContact OE1-NH1 3.98Å; E229-R240 PolarHBondContact OE1-NH1 3.16Å; E229-R240 IonicContact OE1-NH2 2.78Å; E229-R240 PolarHBondContact OE1-NH2 3.12Å; E229-R240 IonicContact OE2-CZ 3.95Å; E229-R240 IonicContact OE2-NH1 3.71Å; E229-R240 IonicContact OE2-NH2 2.79Å; E229-R240 PolarHBondContact OE2-NH2 3.31Å; R240-T265 VanDerWaalsContact CA-O 3.25Å; R240-T265 WeakPolarHBondContact CA-O 3.47Å; R240-T265 WeakPolarHBondContact CD-O 3.23Å
241V98.7Very high90.2Very high0 Ų031.4 Ų31.40%021%0.213CC..EExtended strand (participates in β ladder)trans-114.9133.8155-175.70000107.2Y220 F221 F222 K264 T265 I267 I321 F325 I381Y220-V241 HydrophobicContact CD1-CG1 4.21Å; F221-V241 CarbonylContact O-C 3.6Å; F221-V241 WeakPolarHBondContact O-CA 3.38Å; F222-V241 HydrophobicContact CD1-CG2 3.56Å; F222-V241 HydrophobicContact CE1-CB 4.47Å; F222-V241 HydrophobicContact CE1-CG1 4.34Å; F222-V241 HydrophobicContact CE1-CG2 3.35Å; F222-V241 HydrophobicContact CE2-CG1 4.45Å; F222-V241 HydrophobicContact CG-CG2 4.38Å; F222-V241 HydrophobicContact CZ-CG1 4.2Å; F222-V241 HydrophobicContact CZ-CG2 4.01Å; V241-K264 CarbonylContact O-C 3.27Å; V241-K264 VanDerWaalsContact O-CA 3.31Å; V241-K264 WeakPolarHBondContact O-CA 3.36Å; V241-T265 PolarHBondContact N-O 2.88Å; V241-T265 PolarHBondContact O-N 3.21Å; V241-I267 HydrophobicContact CG2-CB 4.03Å; V241-I267 HydrophobicContact CG2-CD1 3.64Å; V241-I267 HydrophobicContact CG2-CG1 4.42Å; V241-I267 HydrophobicContact CG2-CG2 4.18Å; V241-I321 HydrophobicContact CG1-CG2 4.14Å; V241-F325 HydrophobicContact CG1-CE2 4.17Å; V241-F325 HydrophobicContact CG1-CZ 4.31Å; V241-F325 WeakPolarHBondContact O-CZ 3.33Å; V241-I381 HydrophobicContact CB-CD1 4.02Å; V241-I381 HydrophobicContact CG2-CD1 3.95Å
242A98.6Very high91.5Very high0 Ų035.8 Ų35.80%021%0.211CC..EExtended strand (participates in β ladder)trans-118157166.500000111Y220 F221 F223 F262 L263 K264Y220-A242 CarbonylContact C-O 3.38Å; Y220-A242 VanDerWaalsContact CA-O 3.3Å; Y220-A242 WeakPolarHBondContact CA-O 3.38Å; F221-A242 PolarHBondContact N-O 3.12Å; F221-A242 PolarHBondContact O-N 3.2Å; F223-A242 HydrophobicContact CE1-CB 3.68Å; F223-A242 HydrophobicContact CZ-CB 4.34Å; A242-F262 HydrophobicContact CB-CD2 4.37Å; A242-F262 HydrophobicContact CB-CE2 3.6Å; A242-F262 HydrophobicContact CB-CZ 4.17Å; A242-L263 CarbonylContact C-O 3.46Å; A242-L263 WeakPolarHBondContact CA-O 3.01Å; A242-L263 VanDerWaalsContact CB-O 3.24Å; A242-L263 WeakPolarHBondContact CB-O 3.39Å; A242-K264 HydrophobicContact CB-CB 4.01Å
243R97.8Very high92.8Very high1 Ų137.3 Ų37.30%0.00421%0.214CC..EExtended strand (participates in β ladder)trans-132.3151.9170.174.6173.6-169.3-170.7-1.4111.1Y218 V219 Y220 L263 F325 D326 G354Y218-R243 HydrophobicContact CD1-CG 4.37Å; V219-R243 WeakPolarHBondContact O-CA 3.24Å; Y220-R243 HydrophobicContact CD1-CB 3.9Å; Y220-R243 HydrophobicContact CE1-CB 3.87Å; R243-L263 PolarHBondContact N-O 2.79Å; R243-L263 PolarHBondContact O-N 3.48Å; R243-F325 HydrophobicContact CB-CE2 4.25Å; R243-F325 HydrophobicContact CB-CZ 4.38Å; R243-F325 HydrophobicContact CG-CD1 4.18Å; R243-F325 HydrophobicContact CG-CD2 4.12Å; R243-F325 HydrophobicContact CG-CE1 4.21Å; R243-F325 HydrophobicContact CG-CE2 4.14Å; R243-F325 HydrophobicContact CG-CG 4.15Å; R243-F325 HydrophobicContact CG-CZ 4.18Å; R243-F325 VanDerWaalsContact NH1-CB 3.31Å; R243-D326 IonicContact CZ-OD1 3.22Å; R243-D326 VanDerWaalsContact CZ-OD1 3.25Å; R243-D326 IonicContact NH1-OD1 2.69Å; R243-D326 PolarHBondContact NH1-OD1 3.12Å; R243-D326 IonicContact NH1-OD2 2.63Å; R243-D326 IonicContact NH2-OD1 3.53Å; R243-D326 PolarHBondContact NH2-OD1 3.24Å; R243-G354 PolarHBondContact NH2-O 3.41Å
244I98.1Very high94.2Very high0 Ų033.2 Ų33.20%018%0.183CC..EExtended strand (participates in β ladder)trans-136.1146.8170.457.9178.4000109.4Y162 I176 Y218 V219 F221 W259 F262Y162-I244 HydrophobicContact CD1-CD1 3.5Å; Y162-I244 VanDerWaalsContact CD1-CD1 3.5Å; Y162-I244 HydrophobicContact CE1-CD1 3.6Å; Y162-I244 HydrophobicContact CE1-CG1 4.5Å; I176-I244 HydrophobicContact CG2-CD1 4Å; Y218-I244 CarbonylContact C-O 3.59Å; Y218-I244 WeakPolarHBondContact CA-O 3.29Å; Y218-I244 WeakPolarHBondContact CB-O 3.4Å; Y218-I244 WeakPolarHBondContact CD1-O 3.36Å; V219-I244 HydrophobicContact CB-CD1 4.32Å; V219-I244 HydrophobicContact CB-CG1 3.92Å; V219-I244 PolarHBondContact N-O 3.1Å; V219-I244 PolarHBondContact O-N 2.78Å; F221-I244 HydrophobicContact CE2-CD1 3.65Å; F221-I244 HydrophobicContact CE2-CG1 3.93Å; F221-I244 HydrophobicContact CZ-CD1 4.21Å; I244-W259 HydrophobicContact CD1-CD2 4.41Å; I244-W259 HydrophobicContact CD1-CH2 4.24Å; I244-W259 HydrophobicContact CD1-CZ2 3.97Å; I244-W259 HydrophobicContact CG2-CD2 4.42Å; I244-W259 HydrophobicContact CG2-CG 4.23Å; I244-F262 HydrophobicContact CG2-CB 4.04Å; I244-F262 HydrophobicContact CG2-CD2 3.83Å; I244-F262 HydrophobicContact CG2-CG 4.45Å
245C97.8Very high95.3Very high2 Ų228.2 Ų28.21%0.01416%0.156CC..EExtended strand (participates in β ladder)trans-80132.9174.2-178.10000110.6Y218 S247 D248 S261 C356Y218-C245 HydrophobicContact CD1-CB 4.17Å; Y218-C245 HydrophobicContact CE1-CB 4.01Å; C245-S247 VanDerWaalsContact C-N 3.31Å; C245-S247 PolarHBondContact O-N 3.18Å; C245-S247 PolarHBondContact SG-OG 3.38Å; C245-D248 HydrophobicContact CB-CB 4.34Å; C245-D248 VanDerWaalsContact O-CB 3.24Å; C245-D248 WeakPolarHBondContact O-CB 3.29Å; C245-D248 PolarHBondContact O-N 3.4Å; C245-S261 WeakPolarHBondContact CB-OG 3.16Å; C245-S261 PolarHBondContact N-OG 2.91Å; C245-C356 HydrophobicContact CB-CB 4.13Å; C245-C356 WeakPolarHBondContact CB-SG 3.31Å; C245-C356 WeakPolarHBondContact SG-CA 3.45Å; C245-C356 WeakPolarHBondContact SG-CB 3.49Å; C245-C356 CovalentContact SG-SG 2.03Å; C245-C356 PolarHBondContact SG-SG 2.53Å
246K97.7Very high96Very high9 Ų930.3 Ų30.34%0.03915%0.149CC..THydrogen-bonded Turntrans-63.9-35.7179.5-64.8173.3-170.5-172.10113V150 H152 G153 P155 Y162 R178 D213 G217 Y218 V219 D248V150-K246 HydrophobicContact CG1-CD 3.75Å; V150-K246 HydrophobicContact CG1-CG 4.28Å; H152-K246 WeakPolarHBondContact O-CD 3.39Å; H152-K246 PolarHBondContact O-NZ 3.23Å; G153-K246 CarbonylContact O-C 3.56Å; G153-K246 WeakPolarHBondContact O-CB 3.18Å; P155-K246 WeakPolarHBondContact CD-O 3.28Å; Y162-K246 PolarHBondContact OH-O 2.94Å; R178-K246 PolarHBondContact NH1-O 3.03Å; D213-K246 VanDerWaalsContact OD1-CE 3.31Å; D213-K246 WeakPolarHBondContact OD1-CE 3.44Å; D213-K246 IonicContact OD1-NZ 3.76Å; D213-K246 PolarHBondContact OD1-NZ 2.81Å; D213-K246 IonicContact OD2-NZ 3.38Å; D213-K246 PolarHBondContact OD2-NZ 2.84Å; G217-K246 WeakPolarHBondContact O-CB 3.28Å; G217-K246 VanDerWaalsContact O-CG 3.29Å; G217-K246 WeakPolarHBondContact O-CG 3.33Å; G217-K246 PolarHBondContact O-N 2.85Å; Y218-K246 VanDerWaalsContact O-CE 3.3Å; Y218-K246 WeakPolarHBondContact O-CE 3.35Å; V219-K246 HydrophobicContact CG2-CG 3.85Å; K246-D248 PolarHBondContact O-N 2.8Å
247S96.7Very high96.3Very high44 Ų4433 Ų3331%0.30816%0.158SC..THydrogen-bonded Turntrans-80.63.4-178.768.80000114C245C245-S247 VanDerWaalsContact C-N 3.31Å; C245-S247 PolarHBondContact O-N 3.18Å; C245-S247 PolarHBondContact SG-OG 3.38Å
248D97.2Very high96.5Very high5 Ų532 Ų323%0.02715%0.153CC..  trans-68.4130.5178.2-167-16.5000111.1R178 C245 K246 G250 W259 T260 S261 S360R178-D248 PolarHBondContact NH1-O 3.28Å; R178-D248 VanDerWaalsContact NH1-O 3.13Å; C245-D248 HydrophobicContact CB-CB 4.34Å; C245-D248 VanDerWaalsContact O-CB 3.24Å; C245-D248 WeakPolarHBondContact O-CB 3.29Å; C245-D248 PolarHBondContact O-N 3.4Å; K246-D248 PolarHBondContact O-N 2.8Å; D248-G250 PolarHBondContact OD1-N 2.89Å; D248-W259 HydrophobicContact CB-CE3 3.9Å; D248-W259 HydrophobicContact CB-CZ3 4.1Å; D248-T260 VanDerWaalsContact CG-OG1 3.28Å; D248-T260 PolarHBondContact OD1-N 2.9Å; D248-T260 PolarHBondContact OD1-OG1 2.04Å; D248-T260 PolarHBondContact OD2-N 2.86Å; D248-T260 PolarHBondContact OD2-OG1 3.08Å; D248-S261 WeakPolarHBondContact OD2-CB 3.25Å; D248-S261 PolarHBondContact OD2-N 2.95Å; D248-S261 PolarHBondContact OD2-OG 2.79Å; D248-S360 PolarHBondContact OD1-OG 3.19Å
249V96.6Very high96.5Very high13 Ų1330.8 Ų30.88%0.07915%0.148CC..  trans-12310.4-176.1-64.60000112.4P155 W190 D359 S360 K361P155-V249 HydrophobicContact CB-CG1 4.07Å; P155-V249 HydrophobicContact CG-CG1 3.44Å; P155-V249 VanDerWaalsContact CG-CG1 3.44Å; W190-V249 HydrophobicContact CD2-CG1 4.36Å; W190-V249 HydrophobicContact CE3-CB 4.03Å; W190-V249 HydrophobicContact CE3-CG1 3.53Å; W190-V249 HydrophobicContact CH2-CG1 4.11Å; W190-V249 HydrophobicContact CZ3-CB 3.82Å; W190-V249 HydrophobicContact CZ3-CG1 3.39Å; W190-V249 HydrophobicContact CZ3-CG2 4.32Å; V249-D359 WeakPolarHBondContact CG2-OD1 3.49Å; V249-S360 WeakPolarHBondContact CG2-OG 3.34Å; V249-S360 PolarHBondContact N-OG 3.08Å; V249-K361 HydrophobicContact CG2-CG 4.23Å
250G96.5Very high96.5Very high0 Ų031 Ų310%015%0.15CC..  trans81.9175.5-17900000113.5M193 D248 T258 S360 K361M193-G250 VanDerWaalsContact CE-N 3.26Å; D248-G250 PolarHBondContact OD1-N 2.89Å; G250-T258 WeakPolarHBondContact CA-O 3.38Å; G250-S360 PolarHBondContact N-OG 2.91Å; G250-S360 VanDerWaalsContact N-OG 3.1Å; G250-S360 CarbonylContact O-C 3.29Å; G250-S360 VanDerWaalsContact O-C 3.29Å; G250-S360 WeakPolarHBondContact O-CB 3.43Å; G250-S360 PolarHBondContact O-OG 2.78Å; G250-K361 WeakPolarHBondContact O-CG 3.26Å; G250-K361 PolarHBondContact O-N 2.85Å
251G95.3Very high96.4Very high5 Ų531.2 Ų31.25%0.05215%0.151CC..  trans-86.8165.917600000113.1L254 L255G251-L254 CarbonylContact C-O 3.39Å; G251-L254 VanDerWaalsContact CA-O 3.23Å; G251-L254 WeakPolarHBondContact CA-O 3.39Å; G251-L255 PolarHBondContact N-O 3.07Å
252R92.4Very high96.3Very high177 Ų17731.2 Ų31.267%0.66815%0.151SC*.SBendtrans-77.1-54.2-178.3-177.8-179.9178.9178.60.7112.7K256 K361R252-K256 WeakPolarHBondContact O-CE 3.29Å; R252-K361 HydrophobicContact CB-CB 4.28Å; R252-K361 WeakPolarHBondContact CB-O 3.49Å
253N91.6Very high96.3Very high101 Ų10131.3 Ų31.354%0.5415%0.151SC..SBendtrans-108.5-49.5-176.7-67.1-29.6000111.5
254L93.7Very high96.3Very high51 Ų5131.2 Ų31.227%0.26715%0.151SC..SBendtrans-93.2155170.6-169.862.3000110.3G251 K256 L368 H369 K372G251-L254 CarbonylContact C-O 3.39Å; G251-L254 VanDerWaalsContact CA-O 3.23Å; G251-L254 WeakPolarHBondContact CA-O 3.39Å; L254-K256 VanDerWaalsContact C-N 3.26Å; L254-K256 PolarHBondContact O-N 2.74Å; L254-L368 HydrophobicContact CB-CB 4.17Å; L254-L368 HydrophobicContact CB-CD1 4.14Å; L254-L368 HydrophobicContact CD2-CB 3.83Å; L254-L368 HydrophobicContact CG-CB 4.28Å; L254-H369 HydrophobicContact CD2-CB 4.28Å; L254-K372 HydrophobicContact CD1-CD 4.49Å
255L94.9Very high96.3Very high12 Ų1231.2 Ų31.26%0.06315%0.151CC..SBendtrans52.738.6179.1-56.9-174000113.9I196 W202 G251 Q257 T258 T260 L368 V371 K372I196-L255 HydrophobicContact CD1-CD2 3.8Å; I196-L255 HydrophobicContact CG1-CD2 4.33Å; W202-L255 HydrophobicContact CZ2-CD2 4.43Å; G251-L255 PolarHBondContact N-O 3.07Å; L255-Q257 PolarHBondContact O-N 3.07Å; L255-T258 HydrophobicContact CB-CG2 4.36Å; L255-T258 HydrophobicContact CD2-CG2 3.88Å; L255-T258 PolarHBondContact O-N 3.21Å; L255-T260 HydrophobicContact CB-CG2 4.37Å; L255-T260 HydrophobicContact CD1-CG2 4.4Å; L255-L368 HydrophobicContact CD1-CB 4.47Å; L255-L368 HydrophobicContact CD1-CD2 4.22Å; L255-V371 HydrophobicContact CD1-CB 4.28Å; L255-V371 HydrophobicContact CD1-CG1 3.91Å; L255-K372 HydrophobicContact CD2-CB 4.27Å; L255-K372 HydrophobicContact CD2-CD 4.4Å; L255-K372 HydrophobicContact CD2-CG 4.36Å
256K95.2Very high96.3Very high130 Ų13033.1 Ų33.157%0.56516%0.158SC*.THydrogen-bonded Turntrans-61.2133.8170.7-67.5178.4178.9174.90109.3R252 L254 T258R252-K256 WeakPolarHBondContact O-CE 3.29Å; L254-K256 VanDerWaalsContact C-N 3.26Å; L254-K256 PolarHBondContact O-N 2.74Å; K256-T258 PolarHBondContact O-N 2.72Å; K256-T258 PolarHBondContact O-OG1 3.41Å; K256-T258 VanDerWaalsContact O-OG1 3.04Å
257Q96.4Very high96.3Very high74 Ų7432.8 Ų32.835%0.34616%0.156SC..THydrogen-bonded Turntrans5521.9-177.9-57175.2-4800113.4P191 Y192 M193 S194 L255P191-Q257 HydrophobicContact CB-CG 3.92Å; P191-Q257 VanDerWaalsContact CB-NE2 3.32Å; P191-Q257 HydrophobicContact CG-CG 4.1Å; Y192-Q257 HydrophobicContact CE2-CB 4.11Å; Y192-Q257 PolarHBondContact OH-OE1 2.8Å; Y192-Q257 VanDerWaalsContact OH-OE1 3.14Å; M193-Q257 WeakPolarHBondContact CA-O 3.38Å; M193-Q257 VanDerWaalsContact SD-C 3.59Å; S194-Q257 PolarHBondContact N-O 2.89Å; L255-Q257 PolarHBondContact O-N 3.07Å
258T97.7Very high96.3Very high21 Ų2131.7 Ų31.713%0.12915%0.147CC..BIsolated β-bridgetrans-126.6137-175.9-54.70000109.5M193 S194 I196 W202 G250 L255 K256 T260M193-T258 VanDerWaalsContact CE-O 3.31Å; M193-T258 WeakPolarHBondContact CE-O 3.35Å; S194-T258 VanDerWaalsContact O-CA 3.24Å; S194-T258 WeakPolarHBondContact O-CA 3.19Å; S194-T258 WeakPolarHBondContact O-CG2 3.39Å; I196-T258 HydrophobicContact CD1-CG2 4.47Å; I196-T258 HydrophobicContact CG1-CG2 3.58Å; W202-T258 HydrophobicContact CH2-CG2 3.83Å; W202-T258 HydrophobicContact CZ3-CG2 4.15Å; G250-T258 WeakPolarHBondContact CA-O 3.38Å; L255-T258 HydrophobicContact CB-CG2 4.36Å; L255-T258 HydrophobicContact CD2-CG2 3.88Å; L255-T258 PolarHBondContact O-N 3.21Å; K256-T258 PolarHBondContact O-N 2.72Å; K256-T258 PolarHBondContact O-OG1 3.41Å; K256-T258 VanDerWaalsContact O-OG1 3.04Å; T258-T260 PolarHBondContact O-N 3.43Å
259W97.7Very high96.2Very high0 Ų031.5 Ų31.50%015%0.146CC..  trans-56125.1-178.5-58.4117.6000112Y162 I176 R178 M193 S194 T195 W202 I244 D248 F262Y162-W259 HydrophobicContact CD1-CH2 4.26Å; Y162-W259 HydrophobicContact CD1-CZ2 4.3Å; Y162-W259 AromaticContact CE1-CH2 3.51Å; Y162-W259 HydrophobicContact CE1-CH2 3.51Å; Y162-W259 AromaticContact CE1-CZ2 3.99Å; Y162-W259 HydrophobicContact CE1-CZ2 3.99Å; Y162-W259 HydrophobicContact CE1-CZ3 4.33Å; I176-W259 PolarHBondContact O-NE1 3.25Å; R178-W259 HydrophobicContact CB-CH2 3.65Å; R178-W259 HydrophobicContact CB-CZ2 3.66Å; R178-W259 HydrophobicContact CG-CH2 4.48Å; M193-W259 HydrophobicContact CB-CD2 3.96Å; M193-W259 HydrophobicContact CB-CE3 3.9Å; M193-W259 HydrophobicContact CB-CH2 3.27Å; M193-W259 HydrophobicContact CB-CZ2 3.32Å; M193-W259 HydrophobicContact CB-CZ3 3.58Å; M193-W259 HydrophobicContact CE-CD2 4Å; M193-W259 HydrophobicContact CE-CE3 3.48Å; M193-W259 VanDerWaalsContact CE-CE3 3.48Å; M193-W259 HydrophobicContact CE-CZ3 3.91Å; M193-W259 HydrophobicContact CG-CE3 4.28Å; M193-W259 HydrophobicContact CG-CH2 3.94Å; M193-W259 HydrophobicContact CG-CZ2 4.44Å; M193-W259 HydrophobicContact CG-CZ3 3.85Å; S194-W259 PolarHBondContact O-N 3.06Å; S194-W259 VanDerWaalsContact O-N 3.08Å; T195-W259 VanDerWaalsContact N-CD1 3.34Å; W202-W259 WeakPolarHBondContact CH2-O 3.36Å; W202-W259 HydrophobicContact CZ3-CB 4.41Å; I244-W259 HydrophobicContact CD1-CD2 4.41Å; I244-W259 HydrophobicContact CD1-CH2 4.24Å; I244-W259 HydrophobicContact CD1-CZ2 3.97Å; I244-W259 HydrophobicContact CG2-CD2 4.42Å; I244-W259 HydrophobicContact CG2-CG 4.23Å; D248-W259 HydrophobicContact CB-CE3 3.9Å; D248-W259 HydrophobicContact CB-CZ3 4.1Å; W259-F262 HydrophobicContact CB-CB 3.86Å
260T96.5Very high96.1Very high7 Ų731.5 Ų31.54%0.04315%0.147CC..SBendtrans-91.1-12.9172.562.70000112.5D248 L255 T258 S360 L363 L368 V371D248-T260 VanDerWaalsContact CG-OG1 3.28Å; D248-T260 PolarHBondContact OD1-N 2.9Å; D248-T260 PolarHBondContact OD1-OG1 2.04Å; D248-T260 PolarHBondContact OD2-N 2.86Å; D248-T260 PolarHBondContact OD2-OG1 3.08Å; L255-T260 HydrophobicContact CB-CG2 4.37Å; L255-T260 HydrophobicContact CD1-CG2 4.4Å; T258-T260 PolarHBondContact O-N 3.43Å; T260-S360 VanDerWaalsContact OG1-CB 3.22Å; T260-S360 WeakPolarHBondContact OG1-CB 3.27Å; T260-L363 HydrophobicContact CG2-CD1 4.38Å; T260-L368 HydrophobicContact CG2-CD2 3.47Å; T260-L368 VanDerWaalsContact CG2-CD2 3.47Å; T260-V371 VanDerWaalsContact O-CG1 3.29Å; T260-V371 WeakPolarHBondContact O-CG1 3.38Å; T260-V371 WeakPolarHBondContact O-CG2 3.39Å
261S96.9Very high95.8Very high3 Ų333.7 Ų33.72%0.02116%0.158CC..SBendtrans-1061.8-176.159.60000114.5C245 D248 L263C245-S261 WeakPolarHBondContact CB-OG 3.16Å; C245-S261 PolarHBondContact N-OG 2.91Å; D248-S261 WeakPolarHBondContact OD2-CB 3.25Å; D248-S261 PolarHBondContact OD2-N 2.95Å; D248-S261 PolarHBondContact OD2-OG 2.79Å; S261-L263 PolarHBondContact O-N 3.24Å
262F97.9Very high95.3Very high0 Ų036.7 Ų36.70%018%0.178CC..  trans-67.1121.8-178.7175.3-98.4000111.5I176 T195 W202 L203 A242 I244 W259 K264 A375I176-F262 HydrophobicContact CD1-CD2 4.2Å; I176-F262 HydrophobicContact CD1-CE2 3.57Å; T195-F262 HydrophobicContact CG2-CD2 3.99Å; T195-F262 HydrophobicContact CG2-CE2 4.14Å; T195-F262 HydrophobicContact CG2-CG 4.24Å; T195-F262 HydrophobicContact CG2-CZ 4.49Å; W202-F262 HydrophobicContact CB-CE1 4.3Å; W202-F262 AromaticContact CD2-CD1 3.98Å; W202-F262 HydrophobicContact CD2-CD1 3.98Å; W202-F262 HydrophobicContact CD2-CE1 4.33Å; W202-F262 HydrophobicContact CE3-CB 4.26Å; W202-F262 AromaticContact CE3-CD1 3.41Å; W202-F262 HydrophobicContact CE3-CD1 3.41Å; W202-F262 VanDerWaalsContact CE3-CD1 3.41Å; W202-F262 AromaticContact CE3-CE1 3.96Å; W202-F262 HydrophobicContact CE3-CE1 3.96Å; W202-F262 AromaticContact CE3-CG 3.97Å; W202-F262 HydrophobicContact CE3-CG 3.97Å; W202-F262 HydrophobicContact CH2-CB 4.42Å; W202-F262 HydrophobicContact CZ3-CB 3.78Å; W202-F262 AromaticContact CZ3-CD1 3.83Å; W202-F262 HydrophobicContact CZ3-CD1 3.83Å; W202-F262 HydrophobicContact CZ3-CG 4Å; L203-F262 HydrophobicContact CD2-CZ 4.17Å; L203-F262 HydrophobicContact CG-CZ 4.5Å; A242-F262 HydrophobicContact CB-CD2 4.37Å; A242-F262 HydrophobicContact CB-CE2 3.6Å; A242-F262 HydrophobicContact CB-CZ 4.17Å; I244-F262 HydrophobicContact CG2-CB 4.04Å; I244-F262 HydrophobicContact CG2-CD2 3.83Å; I244-F262 HydrophobicContact CG2-CG 4.45Å; W259-F262 HydrophobicContact CB-CB 3.86Å; F262-K264 HydrophobicContact CZ-CB 4.28Å; F262-K264 HydrophobicContact CZ-CD 4.44Å; F262-A375 HydrophobicContact CD1-CB 4.09Å; F262-A375 HydrophobicContact CE1-CB 4.17Å
263L98Very high94.8Very high2 Ų230.6 Ų30.61%0.0117%0.17CC..EExtended strand (participates in β ladder)trans-134.4149.9170.2-66.7-179000110A242 R243 S261 F325 F330 A375 M377A242-L263 CarbonylContact C-O 3.46Å; A242-L263 WeakPolarHBondContact CA-O 3.01Å; A242-L263 VanDerWaalsContact CB-O 3.24Å; A242-L263 WeakPolarHBondContact CB-O 3.39Å; R243-L263 PolarHBondContact N-O 2.79Å; R243-L263 PolarHBondContact O-N 3.48Å; S261-L263 PolarHBondContact O-N 3.24Å; L263-F325 HydrophobicContact CB-CD1 3.88Å; L263-F325 HydrophobicContact CB-CE1 3.89Å; L263-F325 HydrophobicContact CD1-CD1 4.35Å; L263-F330 HydrophobicContact CD1-CE1 4.07Å; L263-F330 HydrophobicContact CD2-CD1 4.37Å; L263-F330 HydrophobicContact CD2-CE1 3.67Å; L263-A375 WeakPolarHBondContact CA-O 2.96Å; L263-M377 HydrophobicContact CB-SD 4.42Å; L263-M377 HydrophobicContact CD1-SD 3.91Å; L263-M377 HydrophobicContact CD2-SD 4.41Å
264K98.1Very high94.4Very high0 Ų033.3 Ų33.30%019%0.185CC..EExtended strand (participates in β ladder)trans-132.1151.317368.6179.1179-178.20111.9K201 W202 F223 E225 V241 A242 F262 A375 L376 M377K201-K264 WeakPolarHBondContact O-CE 3.13Å; K201-K264 PolarHBondContact O-NZ 3.31Å; W202-K264 WeakPolarHBondContact O-CD 3.18Å; W202-K264 VanDerWaalsContact O-CE 3.28Å; W202-K264 WeakPolarHBondContact O-CE 3.49Å; W202-K264 PolarHBondContact O-NZ 3.37Å; F223-K264 HydrophobicContact CZ-CB 4.4Å; F223-K264 HydrophobicContact CZ-CD 4.26Å; E225-K264 VanDerWaalsContact CD-NZ 3.26Å; E225-K264 WeakPolarHBondContact OE1-CD 3.46Å; E225-K264 WeakPolarHBondContact OE1-CE 3.1Å; E225-K264 IonicContact OE1-NZ 3.74Å; E225-K264 PolarHBondContact OE1-NZ 3.41Å; E225-K264 IonicContact OE2-NZ 2.62Å; E225-K264 PolarHBondContact OE2-NZ 3.4Å; V241-K264 CarbonylContact O-C 3.27Å; V241-K264 VanDerWaalsContact O-CA 3.31Å; V241-K264 WeakPolarHBondContact O-CA 3.36Å; A242-K264 HydrophobicContact CB-CB 4.01Å; F262-K264 HydrophobicContact CZ-CB 4.28Å; F262-K264 HydrophobicContact CZ-CD 4.44Å; K264-A375 PolarHBondContact N-O 2.84Å; K264-L376 HydrophobicContact CG-CD1 4.1Å; K264-L376 WeakPolarHBondContact O-CA 3.09Å; K264-M377 WeakPolarHBondContact O-CG 3.2Å; K264-M377 PolarHBondContact O-N 2.63Å
265T98Very high94.1Very high0 Ų040.1 Ų40.10%021%0.213CC..EExtended strand (participates in β ladder)trans-139.6157.7171.5-172.30000111.1R240 V241 V324 F325 K379 I381R240-T265 VanDerWaalsContact CA-O 3.25Å; R240-T265 WeakPolarHBondContact CA-O 3.47Å; R240-T265 WeakPolarHBondContact CD-O 3.23Å; V241-T265 PolarHBondContact N-O 2.88Å; V241-T265 PolarHBondContact O-N 3.21Å; T265-V324 HydrophobicContact CG2-CG1 4.1Å; T265-F325 HydrophobicContact CG2-CE1 4.11Å; T265-F325 HydrophobicContact CG2-CE2 4.41Å; T265-F325 HydrophobicContact CG2-CZ 3.91Å; T265-K379 PolarHBondContact OG1-O 2.63Å; T265-I381 HydrophobicContact CG2-CD1 3.33Å; T265-I381 HydrophobicContact CG2-CG1 3.79Å
266R97.4Very high93.8Very high41 Ų4142 Ų4216%0.15523%0.226CC..EExtended strand (participates in β ladder)trans-69.2136.8172.1-173.1175.9177.9-156.40109.7S239 Y278 N280 S380 I381S239-R266 WeakPolarHBondContact O-CA 3.09Å; R266-Y278 VanDerWaalsContact NH2-CD1 3.27Å; R266-N280 PolarHBondContact NH2-OD1 2.81Å; R266-S380 CarbonylContact O-C 3.55Å; R266-S380 WeakPolarHBondContact O-CA 3.34Å; R266-S380 WeakPolarHBondContact O-CB 3.45Å; R266-I381 PolarHBondContact O-N 3.28Å
267I97.9Very high93.6Very high2 Ų240.4 Ų40.41%0.0122%0.219CC..BIsolated β-bridgetrans-110.2125.7166.5-171.9165.3000108.5F222 S239 V241 F301 Y316 I381F222-I267 HydrophobicContact CD1-CD1 4.49Å; F222-I267 HydrophobicContact CE1-CD1 4.08Å; S239-I267 PolarHBondContact O-N 2.89Å; V241-I267 HydrophobicContact CG2-CB 4.03Å; V241-I267 HydrophobicContact CG2-CD1 3.64Å; V241-I267 HydrophobicContact CG2-CG1 4.42Å; V241-I267 HydrophobicContact CG2-CG2 4.18Å; I267-F301 HydrophobicContact CG2-CE1 4.33Å; I267-F301 HydrophobicContact CG2-CZ 4.49Å; I267-Y316 HydrophobicContact CD1-CD1 3.82Å; I267-Y316 HydrophobicContact CD1-CD2 3.6Å; I267-Y316 HydrophobicContact CD1-CE1 3.77Å; I267-Y316 HydrophobicContact CD1-CE2 3.56Å; I267-Y316 HydrophobicContact CD1-CG 3.7Å; I267-Y316 HydrophobicContact CG1-CD1 3.87Å; I267-Y316 HydrophobicContact CG1-CD2 4.3Å; I267-Y316 HydrophobicContact CG1-CE1 3.38Å; I267-Y316 HydrophobicContact CG1-CE2 3.88Å; I267-Y316 HydrophobicContact CG1-CG 4.27Å; I267-I381 HydrophobicContact CB-CB 4.46Å; I267-I381 HydrophobicContact CG1-CB 4.21Å; I267-I381 HydrophobicContact CG1-CG2 4.37Å
268N95.5Very high93.4Very high22 Ų2241.1 Ų41.112%0.11822%0.219CC..  trans-108.3129.7-169.9-17737.2000111.4S270 Y278 Y316 I381 P383N268-S270 PolarHBondContact ND2-OG 2.82Å; N268-Y278 VanDerWaalsContact OD1-CD1 3.25Å; N268-Y278 WeakPolarHBondContact OD1-CD1 3.38Å; N268-Y278 WeakPolarHBondContact OD1-CE1 3.46Å; N268-Y316 PolarHBondContact O-OH 3.18Å; N268-I381 PolarHBondContact N-O 2.82Å; N268-P383 WeakPolarHBondContact O-CD 3.39Å
269C95.8Very high93.4Very high1 Ų140.4 Ų40.41%0.00721%0.214CC..  trans-126.5109.6165.9-167.30000108.1F279 F301 C314C269-F279 PolarHBondContact O-N 3.06Å; C269-F301 HydrophobicContact CB-CB 4.35Å; C269-F301 HydrophobicContact CB-CD1 4.06Å; C269-F301 HydrophobicContact CB-CD2 3.51Å; C269-F301 HydrophobicContact CB-CE1 4.22Å; C269-F301 HydrophobicContact CB-CE2 3.73Å; C269-F301 HydrophobicContact CB-CG 3.71Å; C269-F301 HydrophobicContact CB-CZ 4.1Å; C269-C314 WeakPolarHBondContact CA-SG 3.12Å; C269-C314 HydrophobicContact CB-CB 3.86Å; C269-C314 WeakPolarHBondContact CB-SG 3.37Å; C269-C314 WeakPolarHBondContact SG-CB 3.42Å; C269-C314 CovalentContact SG-SG 2.04Å; C269-C314 PolarHBondContact SG-SG 3.4Å
270S93.8Very high93.3Very high12 Ų1242.3 Ų42.38%0.08422%0.224CC..EExtended strand (participates in β ladder)trans-147.3150.1-174.259.10000112.2N268 F277 G393 P394N268-S270 PolarHBondContact ND2-OG 2.82Å; S270-F277 CarbonylContact C-O 3.54Å; S270-F277 WeakPolarHBondContact CA-O 3.31Å; S270-F277 WeakPolarHBondContact CB-O 3.4Å; S270-G393 WeakPolarHBondContact O-CA 3.31Å; S270-P394 VanDerWaalsContact O-CD 3.29Å; S270-P394 WeakPolarHBondContact O-CD 3.25Å
271L90.4Very high93.3Very high46 Ų4643.2 Ų43.224%0.24123%0.228CC..EExtended strand (participates in β ladder)trans-77.7132.1165.5-60.7169.3000108.9P276 F277 F279 P394 Y397L271-P276 WeakPolarHBondContact O-CA 3.29Å; L271-F277 HydrophobicContact CB-CB 4.22Å; L271-F277 HydrophobicContact CD1-CB 4.34Å; L271-F277 HydrophobicContact CD1-CD1 4.37Å; L271-F277 PolarHBondContact N-O 2.88Å; L271-F277 PolarHBondContact O-N 3.11Å; L271-F279 HydrophobicContact CD1-CE2 4.35Å; L271-F279 HydrophobicContact CG-CE2 4.11Å; L271-P394 HydrophobicContact CD2-CG 3.61Å; L271-P394 HydrophobicContact CG-CG 4.44Å; L271-Y397 HydrophobicContact CD1-CD2 4.27Å; L271-Y397 HydrophobicContact CD1-CE2 4.19Å; L271-Y397 HydrophobicContact CD2-CD1 3.78Å; L271-Y397 HydrophobicContact CD2-CD2 4.47Å; L271-Y397 HydrophobicContact CD2-CE1 3.78Å; L271-Y397 HydrophobicContact CD2-CE2 4.48Å; L271-Y397 HydrophobicContact CD2-CG 4.14Å
272S84.9Confident93.3Very high68 Ų6843.1 Ų43.148%0.47623%0.227SC..  trans-67.6148.8174.7-73.20000111.4V392S272-V392 PolarHBondContact OG-O 2.99Å
273G82Confident93.3Very high49 Ų4944.6 Ų44.651%0.50524%0.235SC..SBendtrans162.3173.8178.100000111.1F275G273-F275 PolarHBondContact O-N 3.49Å
274D83.5Confident93.4Very high159 Ų15945.4 Ų45.485%0.8524%0.239SC*.SBendtrans-57.3-31.8176.1-65.6-26.5000111.9
275F86.6Confident93.4Very high194 Ų19445.8 Ų45.885%0.85124%0.241SC*.SBendtrans-12495.7170.6-57.6-80.1000108.9G273 F277G273-F275 PolarHBondContact O-N 3.49Å; F275-F277 PolarHBondContact O-N 3.03Å
276P88.9Confident93.3Very high52 Ų5248.4 Ų48.434%0.33825%0.251SS..  trans-61134.9-176.4-23.733000112.1L271 Y278L271-P276 WeakPolarHBondContact O-CA 3.29Å; P276-Y278 HydrophobicContact CB-CE1 4.37Å; P276-Y278 HydrophobicContact CB-CE2 3.83Å; P276-Y278 VanDerWaalsContact O-CD2 3.26Å; P276-Y278 WeakPolarHBondContact O-CD2 3.27Å; P276-Y278 WeakPolarHBondContact O-CE2 3.39Å
277F91.6Very high93.2Very high95 Ų9549 Ų4942%0.41726%0.256SS..EExtended strand (participates in β ladder)trans-91.9115.7175.5-173-87.7000109.7S270 L271 F275 F279 T303S270-F277 CarbonylContact C-O 3.54Å; S270-F277 WeakPolarHBondContact CA-O 3.31Å; S270-F277 WeakPolarHBondContact CB-O 3.4Å; L271-F277 HydrophobicContact CB-CB 4.22Å; L271-F277 HydrophobicContact CD1-CB 4.34Å; L271-F277 HydrophobicContact CD1-CD1 4.37Å; L271-F277 PolarHBondContact N-O 2.88Å; L271-F277 PolarHBondContact O-N 3.11Å; F275-F277 PolarHBondContact O-N 3.03Å; F277-F279 HydrophobicContact CD1-CD2 4.34Å; F277-F279 HydrophobicContact CD1-CE1 4.34Å; F277-F279 AromaticContact CD1-CE2 3.76Å; F277-F279 HydrophobicContact CD1-CE2 3.76Å; F277-F279 AromaticContact CD1-CZ 3.75Å; F277-F279 HydrophobicContact CD1-CZ 3.75Å; F277-F279 HydrophobicContact CE1-CD1 4.39Å; F277-F279 AromaticContact CE1-CE1 3.82Å; F277-F279 HydrophobicContact CE1-CE1 3.82Å; F277-F279 HydrophobicContact CE1-CE2 4.08Å; F277-F279 AromaticContact CE1-CZ 3.64Å; F277-F279 HydrophobicContact CE1-CZ 3.64Å; F277-T303 HydrophobicContact CE1-CG2 3.53Å; F277-T303 HydrophobicContact CZ-CG2 3.64Å
278Y93.1Very high93Very high89 Ų8949.4 Ų49.435%0.34926%0.259SS..EExtended strand (participates in β ladder)trans-98.6131.5-171.2-66.2-82.4000113.3R266 N268 P276R266-Y278 VanDerWaalsContact NH2-CD1 3.27Å; N268-Y278 VanDerWaalsContact OD1-CD1 3.25Å; N268-Y278 WeakPolarHBondContact OD1-CD1 3.38Å; N268-Y278 WeakPolarHBondContact OD1-CE1 3.46Å; P276-Y278 HydrophobicContact CB-CE1 4.37Å; P276-Y278 HydrophobicContact CB-CE2 3.83Å; P276-Y278 VanDerWaalsContact O-CD2 3.26Å; P276-Y278 WeakPolarHBondContact O-CD2 3.27Å; P276-Y278 WeakPolarHBondContact O-CE2 3.39Å
279F96.3Very high92.6Very high7 Ų753.8 Ų53.83%0.03128%0.277CS..  trans-99.687.3165-57.1-93.8000107.8C269 L271 F277 F301 T302 T303 A312C269-F279 PolarHBondContact O-N 3.06Å; L271-F279 HydrophobicContact CD1-CE2 4.35Å; L271-F279 HydrophobicContact CG-CE2 4.11Å; F277-F279 HydrophobicContact CD1-CD2 4.34Å; F277-F279 HydrophobicContact CD1-CE1 4.34Å; F277-F279 AromaticContact CD1-CE2 3.76Å; F277-F279 HydrophobicContact CD1-CE2 3.76Å; F277-F279 AromaticContact CD1-CZ 3.75Å; F277-F279 HydrophobicContact CD1-CZ 3.75Å; F277-F279 HydrophobicContact CE1-CD1 4.39Å; F277-F279 AromaticContact CE1-CE1 3.82Å; F277-F279 HydrophobicContact CE1-CE1 3.82Å; F277-F279 HydrophobicContact CE1-CE2 4.08Å; F277-F279 AromaticContact CE1-CZ 3.64Å; F277-F279 HydrophobicContact CE1-CZ 3.64Å; F279-F301 HydrophobicContact CB-CB 3.48Å; F279-F301 VanDerWaalsContact CB-CB 3.48Å; F279-F301 HydrophobicContact CB-CG 4.47Å; F279-F301 WeakPolarHBondContact O-CB 3.41Å; F279-F301 VanDerWaalsContact O-CD1 3.29Å; F279-F301 WeakPolarHBondContact O-CD1 3.34Å; F279-T302 CarbonylContact C-O 3.57Å; F279-T303 HydrophobicContact CD1-CG2 3.81Å; F279-T303 HydrophobicContact CE1-CG2 4.03Å; F279-A312 HydrophobicContact CB-CB 4.18Å; F279-A312 HydrophobicContact CD1-CB 3.74Å; F279-A312 HydrophobicContact CD2-CB 3.44Å; F279-A312 VanDerWaalsContact CD2-CB 3.44Å; F279-A312 HydrophobicContact CE1-CB 3.9Å; F279-A312 HydrophobicContact CE2-CB 3.61Å; F279-A312 HydrophobicContact CG-CB 3.51Å; F279-A312 HydrophobicContact CZ-CB 3.84Å
280N95.3Very high91.9Very high39 Ų3954.6 Ų54.621%0.20928%0.282CS..  trans-85.1-12.1-167.3-80.4-37.7000114.4V237 S239 R266 T302V237-N280 VanDerWaalsContact O-CB 3.26Å; V237-N280 WeakPolarHBondContact O-CB 3.33Å; S239-N280 PolarHBondContact N-O 2.63Å; S239-N280 VanDerWaalsContact N-O 3.12Å; S239-N280 PolarHBondContact OG-O 3.2Å; R266-N280 PolarHBondContact NH2-OD1 2.81Å; N280-T302 PolarHBondContact N-O 2.88Å
281E96.6Very high91.1Very high27 Ų2758.2 Ų58.213%0.12631%0.307CS..EExtended strand (participates in β ladder)trans-108.992.1-172.1-63.5-170.1-147.500111.8R224 V237 Q283 F301 T302 N304R224-E281 IonicContact NE-OE2 3.98Å; V237-E281 HydrophobicContact CB-CG 4.28Å; V237-E281 HydrophobicContact CG1-CG 3.93Å; E281-Q283 PolarHBondContact O-N 2.87Å; E281-Q283 PolarHBondContact O-NE2 3.37Å; E281-F301 CarbonylContact O-C 3.1Å; E281-F301 VanDerWaalsContact O-CA 3.29Å; E281-F301 WeakPolarHBondContact O-CA 3.44Å; E281-T302 WeakPolarHBondContact CB-OG1 3.26Å; E281-T302 PolarHBondContact N-O 3.44Å; E281-T302 PolarHBondContact O-N 3.19Å; E281-T302 PolarHBondContact O-OG1 3.03Å; E281-N304 WeakPolarHBondContact OE1-CA 3.4Å
282I98.4Very high90.6Very high0 Ų061.4 Ų61.40%032%0.324CS..EExtended strand (participates in β ladder)trans-61.9129.2173.8-163.8169.3000110.4I209 F222 R224 S239 V285 A299 T300 F301I209-I282 HydrophobicContact CG1-CG2 4.04Å; F222-I282 HydrophobicContact CB-CD1 4.37Å; F222-I282 HydrophobicContact CD1-CD1 4.12Å; R224-I282 HydrophobicContact CB-CG2 4.18Å; R224-I282 PolarHBondContact NH1-O 2.53Å; S239-I282 VanDerWaalsContact OG-CB 3.27Å; S239-I282 WeakPolarHBondContact OG-CB 3.26Å; S239-I282 WeakPolarHBondContact OG-CG2 3.11Å; S239-I282 PolarHBondContact OG-N 2.91Å; I282-V285 HydrophobicContact CD1-CG2 3.49Å; I282-V285 VanDerWaalsContact CD1-CG2 3.49Å; I282-V285 HydrophobicContact CG1-CG2 4.05Å; I282-A299 HydrophobicContact CD1-CB 3.89Å; I282-A299 HydrophobicContact CG1-CB 4.16Å; I282-T300 CarbonylContact C-O 3.5Å; I282-T300 WeakPolarHBondContact CA-O 3.47Å; I282-F301 HydrophobicContact CB-CD1 3.76Å; I282-F301 HydrophobicContact CB-CE1 3.63Å; I282-F301 HydrophobicContact CB-CZ 4.31Å; I282-F301 HydrophobicContact CD1-CE1 3.93Å; I282-F301 HydrophobicContact CD1-CZ 3.84Å; I282-F301 HydrophobicContact CG1-CD1 4.19Å; I282-F301 HydrophobicContact CG1-CE1 3.82Å; I282-F301 HydrophobicContact CG1-CZ 3.98Å
283Q97.9Very high90.4Very high32 Ų3266 Ų6615%0.1534%0.337CS..EExtended strand (participates in β ladder)trans-111.1-28.6-178.2-56.5-57.8-25.400113.4I209 E281 T300 T302I209-Q283 VanDerWaalsContact CG2-O 3.31Å; I209-Q283 WeakPolarHBondContact CG2-O 3.29Å; E281-Q283 PolarHBondContact O-N 2.87Å; E281-Q283 PolarHBondContact O-NE2 3.37Å; Q283-T300 HydrophobicContact CB-CG2 4.15Å; Q283-T300 PolarHBondContact N-O 3.42Å; Q283-T302 HydrophobicContact CG-CG2 3.57Å; Q283-T302 PolarHBondContact NE2-OG1 2.98Å
284D98.5Very high90.8Very high19 Ų1968.5 Ų68.510%0.10234%0.336CS..EExtended strand (participates in β ladder)trans-157.3157.1176.9-15635.6000111.9A299 T300 T404 K405 L406D284-A299 VanDerWaalsContact O-CA 3.26Å; D284-A299 WeakPolarHBondContact O-CA 3.1Å; D284-T300 HydrophobicContact CB-CG2 3.78Å; D284-T300 PolarHBondContact O-N 3.46Å; D284-T300 VanDerWaalsContact O-N 3.08Å; D284-T404 WeakPolarHBondContact CB-O 3.45Å; D284-K405 HydrophobicContact CB-CD 4.44Å; D284-K405 IonicContact OD1-NZ 2.8Å; D284-K405 PolarHBondContact OD1-NZ 2.82Å; D284-K405 VanDerWaalsContact OD2-CA 3.31Å; D284-K405 WeakPolarHBondContact OD2-CA 3.31Å; D284-L406 PolarHBondContact OD2-N 3.46Å
285V98.5Very high91.3Very high8 Ų861.6 Ų61.65%0.04830%0.3CS..EExtended strand (participates in β ladder)trans-138.6127.7175.6-171.50000109.4A210 F212 F222 I282 F297 Y298 A299A210-V285 HydrophobicContact CB-CB 3.87Å; A210-V285 HydrophobicContact CB-CG2 4.24Å; F212-V285 HydrophobicContact CE2-CB 4.07Å; F212-V285 HydrophobicContact CE2-CG1 3.78Å; F212-V285 HydrophobicContact CZ-CB 4.25Å; F212-V285 HydrophobicContact CZ-CG1 4.13Å; F212-V285 WeakPolarHBondContact CZ-O 3.26Å; F222-V285 HydrophobicContact CB-CG2 3.74Å; F222-V285 HydrophobicContact CD1-CG1 4.22Å; F222-V285 HydrophobicContact CD1-CG2 3.79Å; F222-V285 HydrophobicContact CD2-CG1 4.45Å; F222-V285 HydrophobicContact CE1-CG1 4.23Å; F222-V285 HydrophobicContact CE2-CG1 4.48Å; F222-V285 HydrophobicContact CG-CB 4.42Å; F222-V285 HydrophobicContact CG-CG1 4.33Å; F222-V285 HydrophobicContact CG-CG2 3.79Å; F222-V285 HydrophobicContact CZ-CG1 4.37Å; I282-V285 HydrophobicContact CD1-CG2 3.49Å; I282-V285 VanDerWaalsContact CD1-CG2 3.49Å; I282-V285 HydrophobicContact CG1-CG2 4.05Å; V285-F297 HydrophobicContact CG1-CB 3.92Å; V285-F297 HydrophobicContact CG1-CD1 3.99Å; V285-F297 HydrophobicContact CG1-CG 4.41Å; V285-Y298 CarbonylContact C-O 3.58Å; V285-Y298 WeakPolarHBondContact CA-O 3.28Å; V285-A299 HydrophobicContact CG1-CB 4.44Å; V285-A299 HydrophobicContact CG2-CB 3.97Å
286Y97.3Very high91.6Very high54 Ų5453.3 Ų53.321%0.21226%0.263CS..EExtended strand (participates in β ladder)trans-114.1122.3174.6-162.2-92.2000109.8V288 Y298 L406 A407 V408Y286-V288 HydrophobicContact CD1-CG2 3.69Å; Y286-V288 HydrophobicContact CE1-CG2 4.02Å; Y286-Y298 PolarHBondContact N-O 3.17Å; Y286-Y298 PolarHBondContact O-N 2.9Å; Y286-L406 WeakPolarHBondContact CD2-O 3.44Å; Y286-A407 HydrophobicContact CD2-CB 4.46Å; Y286-A407 HydrophobicContact CE2-CB 4.13Å; Y286-V408 HydrophobicContact CD1-CB 3.77Å; Y286-V408 HydrophobicContact CD1-CG2 3.86Å; Y286-V408 HydrophobicContact CE1-CB 4.08Å; Y286-V408 HydrophobicContact CG-CG2 4.32Å
287M95.3Very high92Very high53 Ų5350.8 Ų50.826%0.26125%0.247SC..EExtended strand (participates in β ladder)trans-89.3129.4179.3-178.3-175.266.100110.2F212 V214 T295 F296 F297F212-M287 HydrophobicContact CB-SD 4.15Å; F212-M287 HydrophobicContact CD1-CB 3.72Å; F212-M287 HydrophobicContact CD1-CE 4.11Å; F212-M287 HydrophobicContact CD1-CG 4.4Å; F212-M287 HydrophobicContact CD1-SD 3.94Å; F212-M287 HydrophobicContact CE1-CB 3.54Å; F212-M287 HydrophobicContact CG-CB 4.36Å; F212-M287 HydrophobicContact CG-SD 4.18Å; F212-M287 HydrophobicContact CZ-CB 4.03Å; V214-M287 HydrophobicContact CG1-SD 3.98Å; M287-T295 HydrophobicContact CG-CG2 3.68Å; M287-T295 HydrophobicContact SD-CG2 3.89Å; M287-F296 WeakPolarHBondContact CA-O 3.3Å; M287-F297 HydrophobicContact CB-CD1 4.11Å; M287-F297 HydrophobicContact CB-CE1 4.05Å; M287-F297 HydrophobicContact CG-CD1 4.22Å; M287-F297 HydrophobicContact CG-CE1 3.83Å; M287-F297 HydrophobicContact CG-CZ 4.5Å; M287-F297 HydrophobicContact SD-CE1 4.15Å
288V91.8Very high92.3Very high12 Ų1246.3 Ų46.37%0.07323%0.228CC..EExtended strand (participates in β ladder)trans-123.7131.4177.9-177.60000109.4Y286 T295 F296 Y298 V408 L410Y286-V288 HydrophobicContact CD1-CG2 3.69Å; Y286-V288 HydrophobicContact CE1-CG2 4.02Å; V288-T295 WeakPolarHBondContact O-CA 3.21Å; V288-F296 PolarHBondContact N-O 2.65Å; V288-F296 PolarHBondContact O-N 2.92Å; V288-Y298 HydrophobicContact CB-CD2 4.34Å; V288-Y298 HydrophobicContact CB-CE2 4.04Å; V288-Y298 HydrophobicContact CG2-CD2 3.74Å; V288-Y298 HydrophobicContact CG2-CE2 3.74Å; V288-V408 HydrophobicContact CG2-CB 3.76Å; V288-V408 HydrophobicContact CG2-CG1 3.96Å; V288-V408 HydrophobicContact CG2-CG2 4.39Å; V288-L410 HydrophobicContact CG1-CD1 3.26Å; V288-L410 HydrophobicContact CG1-CD2 4.17Å; V288-L410 HydrophobicContact CG1-CG 3.67Å
289K88.1Confident92.5Very high114 Ų11442.1 Ų42.150%0.49621%0.211SC..EExtended strand (participates in β ladder)trans-104.8123.2169.4-66.1-174.3-179.5-179.80108.9E294 T295K289-E294 WeakPolarHBondContact CA-O 3.33Å; K289-T295 HydrophobicContact CG-CG2 4.47Å
290N81.3Confident92.6Very high18 Ų1841.8 Ų41.810%0.09621%0.21CC..  trans-83.5172.5-179.8-161.910.6000112N292 H293 E294 F296 L410 M417N290-N292 PolarHBondContact O-N 3.25Å; N290-N292 VanDerWaalsContact O-N 3.14Å; N290-H293 WeakPolarHBondContact O-CA 3.41Å; N290-H293 PolarHBondContact O-N 2.91Å; N290-E294 PolarHBondContact N-O 3.43Å; N290-F296 HydrophobicContact CB-CE2 4.25Å; N290-L410 HydrophobicContact CB-CD1 4.46Å; N290-M417 WeakPolarHBondContact ND2-CE 3.41Å; N290-M417 PolarHBondContact ND2-SD 3.02Å; N290-M417 PolarHBondContact OD1-SD 2.83Å
291S76.3Confident92.8Very high88 Ų8839.9 Ų39.962%0.61520%0.2SC*.THydrogen-bonded Turntrans-55.8-29.1177.259.60000113.6H293S291-H293 PolarHBondContact O-N 3.24Å
292N79.4Confident92.8Very high113 Ų11338.7 Ų38.760%0.60419%0.194SC*.THydrogen-bonded Turntrans-85.112.1177.3-61.8-8.4000112.9N290 E294N290-N292 PolarHBondContact O-N 3.25Å; N290-N292 VanDerWaalsContact O-N 3.14Å; N292-E294 HydrophobicContact CB-CG 4.37Å; N292-E294 PolarHBondContact O-N 3.04Å
293H82.1Confident92.7Very high163 Ų16339.2 Ų39.276%0.75520%0.197SC*.SBendtrans618.1-173.6-61.8-92.5000115.4N290 S291N290-H293 WeakPolarHBondContact O-CA 3.41Å; N290-H293 PolarHBondContact O-N 2.91Å; S291-H293 PolarHBondContact O-N 3.24Å
294E89.5Confident92.2Very high103 Ų10342.1 Ų42.148%0.48121%0.214SC..  trans-67.1139.4169.7-66.8-179.1155.300110.5K289 N290 N292 F296K289-E294 WeakPolarHBondContact CA-O 3.33Å; N290-E294 PolarHBondContact N-O 3.43Å; N292-E294 HydrophobicContact CB-CG 4.37Å; N292-E294 PolarHBondContact O-N 3.04Å; E294-F296 HydrophobicContact CB-CD2 4.5Å; E294-F296 HydrophobicContact CB-CE2 3.68Å; E294-F296 HydrophobicContact CB-CZ 4.09Å
295T93.8Very high91.6Very high14 Ų1445.8 Ų45.89%0.08623%0.233CC..EExtended strand (participates in β ladder)trans-110.5126.6-177-59.50000109.9V214 M287 V288 K289 F297 L318V214-T295 HydrophobicContact CG1-CG2 4.43Å; M287-T295 HydrophobicContact CG-CG2 3.68Å; M287-T295 HydrophobicContact SD-CG2 3.89Å; V288-T295 WeakPolarHBondContact O-CA 3.21Å; K289-T295 HydrophobicContact CG-CG2 4.47Å; T295-F297 HydrophobicContact CG2-CE2 4.25Å; T295-F297 HydrophobicContact CG2-CZ 4.05Å; T295-L318 HydrophobicContact CG2-CB 4.38Å; T295-L318 HydrophobicContact CG2-CD2 4.38Å; T295-L318 WeakPolarHBondContact O-CB 3.36Å; T295-L318 PolarHBondContact O-N 3.09Å
296F94.5Very high90.9Very high19 Ų1952.9 Ų52.98%0.08327%0.27CS..EExtended strand (participates in β ladder)trans-120.6147179.4-63-81.7000110.4M287 V288 N290 E294 Y298 I315 Y316 I384M287-F296 WeakPolarHBondContact CA-O 3.3Å; V288-F296 PolarHBondContact N-O 2.65Å; V288-F296 PolarHBondContact O-N 2.92Å; N290-F296 HydrophobicContact CB-CE2 4.25Å; E294-F296 HydrophobicContact CB-CD2 4.5Å; E294-F296 HydrophobicContact CB-CE2 3.68Å; E294-F296 HydrophobicContact CB-CZ 4.09Å; F296-Y298 HydrophobicContact CB-CE2 4.14Å; F296-I315 HydrophobicContact CB-CG2 4.25Å; F296-I315 HydrophobicContact CD1-CG2 4.29Å; F296-Y316 CarbonylContact C-O 3.52Å; F296-Y316 VanDerWaalsContact CA-O 3.31Å; F296-Y316 WeakPolarHBondContact CA-O 3.47Å; F296-I384 HydrophobicContact CD1-CD1 3.5Å; F296-I384 VanDerWaalsContact CD1-CD1 3.5Å; F296-I384 HydrophobicContact CE1-CD1 3.47Å; F296-I384 VanDerWaalsContact CE1-CD1 3.47Å
297F97Very high90Very high0 Ų052.8 Ų52.80%029%0.286CS..EExtended strand (participates in β ladder)trans-116.2114.3175.7-59.9-81.7000108.9F212 V214 F222 V285 M287 T295 I315 Y316 L318 I321F212-F297 HydrophobicContact CB-CE1 4.38Å; F212-F297 HydrophobicContact CD2-CD1 4.14Å; F212-F297 AromaticContact CD2-CE1 3.68Å; F212-F297 HydrophobicContact CD2-CE1 3.68Å; F212-F297 HydrophobicContact CE2-CD1 4.1Å; F212-F297 HydrophobicContact CE2-CE1 4.1Å; F212-F297 HydrophobicContact CG-CE1 4.02Å; V214-F297 HydrophobicContact CG1-CZ 3.98Å; F222-F297 HydrophobicContact CE1-CB 4.43Å; F222-F297 HydrophobicContact CE1-CG 4.38Å; F222-F297 AromaticContact CE2-CD1 3.93Å; F222-F297 HydrophobicContact CE2-CD1 3.93Å; F222-F297 AromaticContact CE2-CE1 3.92Å; F222-F297 HydrophobicContact CE2-CE1 3.92Å; F222-F297 HydrophobicContact CE2-CG 4.42Å; F222-F297 HydrophobicContact CE2-CZ 4.4Å; F222-F297 HydrophobicContact CZ-CB 4.22Å; F222-F297 AromaticContact CZ-CD1 3.67Å; F222-F297 HydrophobicContact CZ-CD1 3.67Å; F222-F297 HydrophobicContact CZ-CD2 4.05Å; F222-F297 AromaticContact CZ-CE1 3.97Å; F222-F297 HydrophobicContact CZ-CE1 3.97Å; F222-F297 HydrophobicContact CZ-CE2 4.32Å; F222-F297 AromaticContact CZ-CG 3.7Å; F222-F297 HydrophobicContact CZ-CG 3.7Å; F222-F297 HydrophobicContact CZ-CZ 4.27Å; V285-F297 HydrophobicContact CG1-CB 3.92Å; V285-F297 HydrophobicContact CG1-CD1 3.99Å; V285-F297 HydrophobicContact CG1-CG 4.41Å; M287-F297 HydrophobicContact CB-CD1 4.11Å; M287-F297 HydrophobicContact CB-CE1 4.05Å; M287-F297 HydrophobicContact CG-CD1 4.22Å; M287-F297 HydrophobicContact CG-CE1 3.83Å; M287-F297 HydrophobicContact CG-CZ 4.5Å; M287-F297 HydrophobicContact SD-CE1 4.15Å; T295-F297 HydrophobicContact CG2-CE2 4.25Å; T295-F297 HydrophobicContact CG2-CZ 4.05Å; F297-I315 WeakPolarHBondContact O-CA 3.5Å; F297-Y316 PolarHBondContact N-O 3.21Å; F297-Y316 PolarHBondContact O-N 2.79Å; F297-L318 HydrophobicContact CE2-CB 4.01Å; F297-L318 HydrophobicContact CE2-CD1 4.02Å; F297-L318 HydrophobicContact CZ-CD1 4.36Å; F297-I321 HydrophobicContact CD2-CD1 3.55Å; F297-I321 HydrophobicContact CE2-CD1 3.69Å
298Y97.3Very high89.4Confident1 Ų157.8 Ų57.80%0.00431%0.307CS..EExtended strand (participates in β ladder)trans-90.8120.5171.2-70-108.3000107.1V285 Y286 V288 F296 I315 V408 I421 Y442V285-Y298 CarbonylContact C-O 3.58Å; V285-Y298 WeakPolarHBondContact CA-O 3.28Å; Y286-Y298 PolarHBondContact N-O 3.17Å; Y286-Y298 PolarHBondContact O-N 2.9Å; V288-Y298 HydrophobicContact CB-CD2 4.34Å; V288-Y298 HydrophobicContact CB-CE2 4.04Å; V288-Y298 HydrophobicContact CG2-CD2 3.74Å; V288-Y298 HydrophobicContact CG2-CE2 3.74Å; F296-Y298 HydrophobicContact CB-CE2 4.14Å; Y298-I315 HydrophobicContact CD1-CD1 3.9Å; Y298-I315 HydrophobicContact CD1-CG1 3.68Å; Y298-I315 HydrophobicContact CD2-CG2 4.46Å; Y298-I315 HydrophobicContact CE1-CD1 3.31Å; Y298-I315 HydrophobicContact CE1-CG1 3.65Å; Y298-I315 HydrophobicContact CE1-CG2 4.41Å; Y298-I315 HydrophobicContact CE2-CG2 4.25Å; Y298-I315 HydrophobicContact CG-CG1 4.34Å; Y298-V408 HydrophobicContact CD1-CG1 4.44Å; Y298-V408 HydrophobicContact CD1-CG2 3.97Å; Y298-V408 HydrophobicContact CD2-CG1 4.38Å; Y298-V408 HydrophobicContact CD2-CG2 4.06Å; Y298-V408 HydrophobicContact CE1-CG1 4.17Å; Y298-V408 HydrophobicContact CE2-CG1 4.13Å; Y298-V408 HydrophobicContact CG-CG2 3.72Å; Y298-I421 HydrophobicContact CD1-CD1 3.81Å; Y298-I421 HydrophobicContact CD1-CG1 3.88Å; Y298-I421 HydrophobicContact CE1-CD1 3.89Å; Y298-I421 HydrophobicContact CE1-CG1 4Å; Y298-Y442 PolarHBondContact OH-OH 2.97Å
299A98.4Very high89.3Confident0 Ų058.6 Ų58.60%031%0.313CS..EExtended strand (participates in β ladder)trans-128.2137.8-177.900000110.9I282 D284 V285 F301 I313 C314 Y316I282-A299 HydrophobicContact CD1-CB 3.89Å; I282-A299 HydrophobicContact CG1-CB 4.16Å; D284-A299 VanDerWaalsContact O-CA 3.26Å; D284-A299 WeakPolarHBondContact O-CA 3.1Å; V285-A299 HydrophobicContact CG1-CB 4.44Å; V285-A299 HydrophobicContact CG2-CB 3.97Å; A299-F301 HydrophobicContact CB-CD2 4.38Å; A299-F301 HydrophobicContact CB-CE2 3.48Å; A299-F301 VanDerWaalsContact CB-CE2 3.48Å; A299-F301 HydrophobicContact CB-CZ 3.83Å; A299-F301 WeakPolarHBondContact O-CD2 3.47Å; A299-F301 WeakPolarHBondContact O-CE2 3.44Å; A299-I313 WeakPolarHBondContact O-CA 3.31Å; A299-C314 PolarHBondContact N-O 3.39Å; A299-C314 PolarHBondContact O-N 3.43Å; A299-Y316 HydrophobicContact CB-CE2 4.14Å
300T98.4Very high89.7Confident0 Ų053.4 Ų53.40%029%0.292CS..EExtended strand (participates in β ladder)trans-101.5137.6173.8-1780000109.7I282 Q283 D284 A312 L403 L406I282-T300 CarbonylContact C-O 3.5Å; I282-T300 WeakPolarHBondContact CA-O 3.47Å; Q283-T300 HydrophobicContact CB-CG2 4.15Å; Q283-T300 PolarHBondContact N-O 3.42Å; D284-T300 HydrophobicContact CB-CG2 3.78Å; D284-T300 PolarHBondContact O-N 3.46Å; D284-T300 VanDerWaalsContact O-N 3.08Å; T300-A312 CarbonylContact C-O 3.32Å; T300-A312 WeakPolarHBondContact CA-O 3.38Å; T300-L403 HydrophobicContact CG2-CB 4.48Å; T300-L403 WeakPolarHBondContact OG1-CB 3.48Å; T300-L406 HydrophobicContact CG2-CD1 4.02Å; T300-L406 HydrophobicContact CG2-CD2 4.27Å; T300-L406 HydrophobicContact CG2-CG 3.83Å
301F98.4Very high90.4Very high0 Ų052.5 Ų52.50%029%0.287CS..EExtended strand (participates in β ladder)trans-125.9151.6-177.1-60.4-102000109.5I267 C269 F279 E281 I282 A299 S311 A312 C314 Y316I267-F301 HydrophobicContact CG2-CE1 4.33Å; I267-F301 HydrophobicContact CG2-CZ 4.49Å; C269-F301 HydrophobicContact CB-CB 4.35Å; C269-F301 HydrophobicContact CB-CD1 4.06Å; C269-F301 HydrophobicContact CB-CD2 3.51Å; C269-F301 HydrophobicContact CB-CE1 4.22Å; C269-F301 HydrophobicContact CB-CE2 3.73Å; C269-F301 HydrophobicContact CB-CG 3.71Å; C269-F301 HydrophobicContact CB-CZ 4.1Å; F279-F301 HydrophobicContact CB-CB 3.48Å; F279-F301 VanDerWaalsContact CB-CB 3.48Å; F279-F301 HydrophobicContact CB-CG 4.47Å; F279-F301 WeakPolarHBondContact O-CB 3.41Å; F279-F301 VanDerWaalsContact O-CD1 3.29Å; F279-F301 WeakPolarHBondContact O-CD1 3.34Å; E281-F301 CarbonylContact O-C 3.1Å; E281-F301 VanDerWaalsContact O-CA 3.29Å; E281-F301 WeakPolarHBondContact O-CA 3.44Å; I282-F301 HydrophobicContact CB-CD1 3.76Å; I282-F301 HydrophobicContact CB-CE1 3.63Å; I282-F301 HydrophobicContact CB-CZ 4.31Å; I282-F301 HydrophobicContact CD1-CE1 3.93Å; I282-F301 HydrophobicContact CD1-CZ 3.84Å; I282-F301 HydrophobicContact CG1-CD1 4.19Å; I282-F301 HydrophobicContact CG1-CE1 3.82Å; I282-F301 HydrophobicContact CG1-CZ 3.98Å; A299-F301 HydrophobicContact CB-CD2 4.38Å; A299-F301 HydrophobicContact CB-CE2 3.48Å; A299-F301 VanDerWaalsContact CB-CE2 3.48Å; A299-F301 HydrophobicContact CB-CZ 3.83Å; A299-F301 WeakPolarHBondContact O-CD2 3.47Å; A299-F301 WeakPolarHBondContact O-CE2 3.44Å; F301-S311 CarbonylContact O-C 3.45Å; F301-S311 WeakPolarHBondContact O-CA 3.43Å; F301-S311 WeakPolarHBondContact O-CB 3.32Å; F301-S311 PolarHBondContact O-OG 3.25Å; F301-A312 PolarHBondContact N-O 3.14Å; F301-A312 PolarHBondContact O-N 3.13Å; F301-C314 HydrophobicContact CD2-CB 4.41Å; F301-C314 HydrophobicContact CE2-CB 3.96Å; F301-Y316 AromaticContact CE2-CE2 3.86Å; F301-Y316 HydrophobicContact CE2-CE2 3.86Å; F301-Y316 WeakPolarHBondContact CE2-OH 3.36Å; F301-Y316 AromaticContact CZ-CE2 3.85Å; F301-Y316 HydrophobicContact CZ-CE2 3.85Å; F301-Y316 AromaticContact CZ-CZ 3.93Å; F301-Y316 WeakPolarHBondContact CZ-OH 3.44Å
302T97.4Very high91.4Very high1 Ų148.3 Ų48.31%0.00626%0.258CS..EExtended strand (participates in β ladder)trans-120.4160.9170.762.20000110.5F279 N280 E281 Q283 G310 S311 I402F279-T302 CarbonylContact C-O 3.57Å; N280-T302 PolarHBondContact N-O 2.88Å; E281-T302 WeakPolarHBondContact CB-OG1 3.26Å; E281-T302 PolarHBondContact N-O 3.44Å; E281-T302 PolarHBondContact O-N 3.19Å; E281-T302 PolarHBondContact O-OG1 3.03Å; Q283-T302 HydrophobicContact CG-CG2 3.57Å; Q283-T302 PolarHBondContact NE2-OG1 2.98Å; T302-G310 VanDerWaalsContact CA-O 3.28Å; T302-G310 WeakPolarHBondContact CA-O 3.42Å; T302-S311 VanDerWaalsContact CG2-OG 3.29Å; T302-S311 WeakPolarHBondContact CG2-OG 3.27Å; T302-I402 HydrophobicContact CG2-CD1 4.12Å; T302-I402 HydrophobicContact CG2-CG2 3.89Å
303T94.9Very high92.2Very high12 Ų1243 Ų437%0.07423%0.229CC..  trans-74.9175.3158550000110.5F277 F279 F308 S309 G310F277-T303 HydrophobicContact CE1-CG2 3.53Å; F277-T303 HydrophobicContact CZ-CG2 3.64Å; F279-T303 HydrophobicContact CD1-CG2 3.81Å; F279-T303 HydrophobicContact CE1-CG2 4.03Å; T303-F308 WeakPolarHBondContact CB-O 3.35Å; T303-F308 PolarHBondContact OG1-O 3.13Å; T303-S309 WeakPolarHBondContact OG1-CA 3.5Å; T303-G310 PolarHBondContact N-O 2.04Å; T303-G310 PolarHBondContact OG1-N 2.98Å; T303-G310 PolarHBondContact OG1-O 2.94Å
304N89.3Confident92.9Very high92 Ų9235.2 Ų35.249%0.49219%0.193SC..  trans-63.5133.6167.2-175.6-23.5000109.7E281 N306E281-N304 WeakPolarHBondContact OE1-CA 3.4Å; N304-N306 VanDerWaalsContact C-N 3.27Å; N304-N306 PolarHBondContact O-N 2.92Å; N304-N306 WeakPolarHBondContact OD1-CB 3.41Å; N304-N306 PolarHBondContact OD1-N 3.02Å
305L84.9Confident93.1Very high97 Ų9730.4 Ų30.451%0.50817%0.171SC..THydrogen-bonded Turntrans-71.1-17.4-178.1-58.9178.5000113.7G307 I402L305-G307 PolarHBondContact O-N 2.85Å; L305-I402 HydrophobicContact CD2-CD1 3.65Å; L305-I402 HydrophobicContact CD2-CG1 4.06Å
306N83.7Confident93.2Very high156 Ų15629.8 Ų29.883%0.83417%0.167SC*.THydrogen-bonded Turntrans-77.520.9-178.2-67.4-23000114.4N304N304-N306 VanDerWaalsContact C-N 3.27Å; N304-N306 PolarHBondContact O-N 2.92Å; N304-N306 WeakPolarHBondContact OD1-CB 3.41Å; N304-N306 PolarHBondContact OD1-N 3.02Å
307G78.3Confident93.2Very high53 Ų5329.5 Ų29.555%0.54617%0.167SC..SBendtrans-169.7-129.9-176.900000112.2L305 S309L305-G307 PolarHBondContact O-N 2.85Å; G307-S309 PolarHBondContact O-N 2.9Å
308F83.2Confident93.2Very high157 Ų15730.5 Ų30.569%0.68917%0.172SC*.SBendtrans-66.1107.4174-63.6-70.3000110T303T303-F308 WeakPolarHBondContact CB-O 3.35Å; T303-F308 PolarHBondContact OG1-O 3.13Å
309S90Very high93.1Very high30 Ų3033.8 Ų33.821%0.2120%0.2CC..  trans-84.3135.4176.2-72.60000110T303 G307 D400T303-S309 WeakPolarHBondContact OG1-CA 3.5Å; G307-S309 PolarHBondContact O-N 2.9Å; S309-D400 WeakPolarHBondContact O-CA 3.47Å; S309-D400 PolarHBondContact O-N 2.72Å
310G95Very high93Very high4 Ų437.3 Ų37.34%0.04122%0.219CC..EExtended strand (participates in β ladder)trans-172.8160.117400000111.2T302 T303 K398 V401T302-G310 VanDerWaalsContact CA-O 3.28Å; T302-G310 WeakPolarHBondContact CA-O 3.42Å; T303-G310 PolarHBondContact N-O 2.04Å; T303-G310 PolarHBondContact OG1-N 2.98Å; T303-G310 PolarHBondContact OG1-O 2.94Å; G310-K398 VanDerWaalsContact CA-O 3.31Å; G310-K398 WeakPolarHBondContact CA-O 3.31Å; G310-V401 CarbonylContact C-O 3.5Å
311S97.5Very high93Very high0 Ų037.3 Ų37.30%022%0.219CC..EExtended strand (participates in β ladder)trans-125.1154.4179.9-80.10000112.6F301 T302 Y397 K398 V401 I402 L403F301-S311 CarbonylContact O-C 3.45Å; F301-S311 WeakPolarHBondContact O-CA 3.43Å; F301-S311 WeakPolarHBondContact O-CB 3.32Å; F301-S311 PolarHBondContact O-OG 3.25Å; T302-S311 VanDerWaalsContact CG2-OG 3.29Å; T302-S311 WeakPolarHBondContact CG2-OG 3.27Å; S311-Y397 CarbonylContact O-C 3.54Å; S311-Y397 WeakPolarHBondContact O-CA 3.17Å; S311-K398 PolarHBondContact N-O 2.77Å; S311-K398 PolarHBondContact O-N 2.85Å; S311-V401 VanDerWaalsContact CB-O 3.28Å; S311-V401 WeakPolarHBondContact CB-O 3.29Å; S311-V401 PolarHBondContact N-O 2.79Å; S311-V401 VanDerWaalsContact N-O 3.11Å; S311-V401 PolarHBondContact OG-O 2.62Å; S311-I402 WeakPolarHBondContact OG-CA 3.27Å; S311-L403 PolarHBondContact OG-N 3.2Å
312A96.4Very high92.9Very high0 Ų040.8 Ų40.80%023%0.234CC..EExtended strand (participates in β ladder)trans-140.9148.5174.900000111F279 T300 F301 P394 F396F279-A312 HydrophobicContact CB-CB 4.18Å; F279-A312 HydrophobicContact CD1-CB 3.74Å; F279-A312 HydrophobicContact CD2-CB 3.44Å; F279-A312 VanDerWaalsContact CD2-CB 3.44Å; F279-A312 HydrophobicContact CE1-CB 3.9Å; F279-A312 HydrophobicContact CE2-CB 3.61Å; F279-A312 HydrophobicContact CG-CB 3.51Å; F279-A312 HydrophobicContact CZ-CB 3.84Å; T300-A312 CarbonylContact C-O 3.32Å; T300-A312 WeakPolarHBondContact CA-O 3.38Å; F301-A312 PolarHBondContact N-O 3.14Å; F301-A312 PolarHBondContact O-N 3.13Å; A312-P394 HydrophobicContact CB-CB 3.76Å; A312-P394 HydrophobicContact CB-CG 4.16Å; A312-F396 CarbonylContact C-O 3.58Å; A312-F396 VanDerWaalsContact CA-O 3.24Å; A312-F396 WeakPolarHBondContact CA-O 3.44Å
313I96.6Very high92.9Very high0 Ų045.6 Ų45.60%026%0.256CS..EExtended strand (participates in β ladder)trans-112.7125.7174.6-54179000107.9A299 P394 I395 F396 L403 L406 I421 A423 I433A299-I313 WeakPolarHBondContact O-CA 3.31Å; I313-P394 CarbonylContact O-C 3.57Å; I313-P394 VanDerWaalsContact O-CA 3.29Å; I313-P394 WeakPolarHBondContact O-CA 3.49Å; I313-P394 WeakPolarHBondContact O-CB 3.25Å; I313-I395 HydrophobicContact CB-CD1 4.4Å; I313-I395 HydrophobicContact CB-CG1 4.16Å; I313-I395 HydrophobicContact CG2-CD1 3.94Å; I313-I395 HydrophobicContact CG2-CG1 4.09Å; I313-I395 WeakPolarHBondContact O-CG1 3.49Å; I313-I395 PolarHBondContact O-N 2.83Å; I313-F396 HydrophobicContact CB-CB 4.39Å; I313-F396 HydrophobicContact CD1-CB 4.46Å; I313-F396 HydrophobicContact CD1-CD1 4.14Å; I313-F396 HydrophobicContact CG1-CD1 4.33Å; I313-F396 PolarHBondContact N-O 2.85Å; I313-L403 HydrophobicContact CD1-CD1 3.8Å; I313-L403 HydrophobicContact CG1-CD1 3.72Å; I313-L406 HydrophobicContact CD1-CD2 4Å; I313-L406 HydrophobicContact CG2-CD1 4.49Å; I313-I421 HydrophobicContact CD1-CG2 3.93Å; I313-I421 HydrophobicContact CG2-CD1 4.36Å; I313-A423 HydrophobicContact CD1-CB 4.18Å; I313-I433 HydrophobicContact CD1-CD1 3.67Å
314C95.9Very high93.1Very high0 Ų045.6 Ų45.60%026%0.256CS..EExtended strand (participates in β ladder)trans-122.1149.5176.1-80.70000110C269 A299 F301 Y316 P383 P394C269-C314 WeakPolarHBondContact CA-SG 3.12Å; C269-C314 HydrophobicContact CB-CB 3.86Å; C269-C314 WeakPolarHBondContact CB-SG 3.37Å; C269-C314 WeakPolarHBondContact SG-CB 3.42Å; C269-C314 CovalentContact SG-SG 2.04Å; C269-C314 PolarHBondContact SG-SG 3.4Å; A299-C314 PolarHBondContact N-O 3.39Å; A299-C314 PolarHBondContact O-N 3.43Å; F301-C314 HydrophobicContact CD2-CB 4.41Å; F301-C314 HydrophobicContact CE2-CB 3.96Å; C314-Y316 HydrophobicContact CB-CE2 3.66Å; C314-Y316 WeakPolarHBondContact CB-OH 3.36Å; C314-P383 HydrophobicContact CB-CB 3.99Å; C314-P394 VanDerWaalsContact SG-CA 3.55Å
315I94.6Very high93.5Very high3 Ų341.2 Ų41.22%0.01523%0.233CC..EExtended strand (participates in β ladder)trans-114.8137.8178.3-49.3176.5000108.8F296 F297 Y298 P383 I384 I395 Y442F296-I315 HydrophobicContact CB-CG2 4.25Å; F296-I315 HydrophobicContact CD1-CG2 4.29Å; F297-I315 WeakPolarHBondContact O-CA 3.5Å; Y298-I315 HydrophobicContact CD1-CD1 3.9Å; Y298-I315 HydrophobicContact CD1-CG1 3.68Å; Y298-I315 HydrophobicContact CD2-CG2 4.46Å; Y298-I315 HydrophobicContact CE1-CD1 3.31Å; Y298-I315 HydrophobicContact CE1-CG1 3.65Å; Y298-I315 HydrophobicContact CE1-CG2 4.41Å; Y298-I315 HydrophobicContact CE2-CG2 4.25Å; Y298-I315 HydrophobicContact CG-CG1 4.34Å; I315-P383 CarbonylContact O-C 3.55Å; I315-P383 VanDerWaalsContact O-CA 3.27Å; I315-P383 WeakPolarHBondContact O-CA 3.36Å; I315-I384 HydrophobicContact CG2-CD1 3.93Å; I315-I384 PolarHBondContact O-N 3.03Å; I315-I395 HydrophobicContact CD1-CD1 3.81Å; I315-I395 HydrophobicContact CD1-CG1 4.37Å; I315-I395 HydrophobicContact CD1-CG2 3.97Å; I315-I395 HydrophobicContact CG1-CD1 3.94Å; I315-I395 HydrophobicContact CG1-CG1 4.22Å; I315-I395 HydrophobicContact CG1-CG2 4.26Å; I315-Y442 HydrophobicContact CD1-CD1 3.6Å; I315-Y442 HydrophobicContact CD1-CD2 4.18Å; I315-Y442 HydrophobicContact CD1-CE1 3.44Å; I315-Y442 VanDerWaalsContact CD1-CE1 3.44Å; I315-Y442 HydrophobicContact CD1-CE2 4.07Å; I315-Y442 HydrophobicContact CD1-CG 3.96Å; I315-Y442 HydrophobicContact CG2-CE2 4.42Å
316Y95.8Very high94Very high0 Ų038.7 Ų38.70%022%0.22CC..EExtended strand (participates in β ladder)trans-130142.6179.1-52.4-86.6000110.6I267 N268 F296 F297 A299 F301 C314 I381 A382 P383I267-Y316 HydrophobicContact CD1-CD1 3.82Å; I267-Y316 HydrophobicContact CD1-CD2 3.6Å; I267-Y316 HydrophobicContact CD1-CE1 3.77Å; I267-Y316 HydrophobicContact CD1-CE2 3.56Å; I267-Y316 HydrophobicContact CD1-CG 3.7Å; I267-Y316 HydrophobicContact CG1-CD1 3.87Å; I267-Y316 HydrophobicContact CG1-CD2 4.3Å; I267-Y316 HydrophobicContact CG1-CE1 3.38Å; I267-Y316 HydrophobicContact CG1-CE2 3.88Å; I267-Y316 HydrophobicContact CG1-CG 4.27Å; N268-Y316 PolarHBondContact O-OH 3.18Å; F296-Y316 CarbonylContact C-O 3.52Å; F296-Y316 VanDerWaalsContact CA-O 3.31Å; F296-Y316 WeakPolarHBondContact CA-O 3.47Å; F297-Y316 PolarHBondContact N-O 3.21Å; F297-Y316 PolarHBondContact O-N 2.79Å; A299-Y316 HydrophobicContact CB-CE2 4.14Å; F301-Y316 AromaticContact CE2-CE2 3.86Å; F301-Y316 HydrophobicContact CE2-CE2 3.86Å; F301-Y316 WeakPolarHBondContact CE2-OH 3.36Å; F301-Y316 AromaticContact CZ-CE2 3.85Å; F301-Y316 HydrophobicContact CZ-CE2 3.85Å; F301-Y316 AromaticContact CZ-CZ 3.93Å; F301-Y316 WeakPolarHBondContact CZ-OH 3.44Å; C314-Y316 HydrophobicContact CB-CE2 3.66Å; C314-Y316 WeakPolarHBondContact CB-OH 3.36Å; Y316-I381 HydrophobicContact CD1-CG2 3.67Å; Y316-I381 HydrophobicContact CE1-CG2 4.3Å; Y316-I381 HydrophobicContact CG-CG2 4.45Å; Y316-A382 WeakPolarHBondContact CD1-O 3.4Å; Y316-P383 HydrophobicContact CD1-CB 4.47Å; Y316-P383 HydrophobicContact CE1-CB 4.05Å
317S94.5Very high94.5Very high14 Ų1437.1 Ų37.110%0.09821%0.207CC..EExtended strand (participates in β ladder)trans-90.7143.8173.7840000110.7A319 D320 I321S317-A319 PolarHBondContact O-N 3.11Å; S317-D320 PolarHBondContact O-N 2.92Å; S317-D320 WeakPolarHBondContact OG-CB 3.47Å; S317-D320 PolarHBondContact OG-N 2.8Å; S317-D320 PolarHBondContact OG-OD2 2.78Å; S317-I321 WeakPolarHBondContact O-CG1 3.48Å; S317-I321 PolarHBondContact O-N 3.08Å
318L96.8Very high95.4Very high20 Ų2034.7 Ų34.711%0.10518%0.182CC..Hα-helixtrans-60.8-31.8171.5178.762000111.5V214 Y220 T295 F297 I321 K322V214-L318 HydrophobicContact CB-CD2 3.9Å; V214-L318 HydrophobicContact CG1-CD1 4.48Å; V214-L318 HydrophobicContact CG1-CD2 4.21Å; V214-L318 HydrophobicContact CG2-CD1 4.25Å; V214-L318 HydrophobicContact CG2-CD2 3.76Å; Y220-L318 HydrophobicContact CE1-CD1 4.19Å; Y220-L318 HydrophobicContact CE2-CD1 4.05Å; T295-L318 HydrophobicContact CG2-CB 4.38Å; T295-L318 HydrophobicContact CG2-CD2 4.38Å; T295-L318 WeakPolarHBondContact O-CB 3.36Å; T295-L318 PolarHBondContact O-N 3.09Å; F297-L318 HydrophobicContact CE2-CB 4.01Å; F297-L318 HydrophobicContact CE2-CD1 4.02Å; F297-L318 HydrophobicContact CZ-CD1 4.36Å; L318-I321 PolarHBondContact O-N 3.11Å; L318-K322 HydrophobicContact CD1-CD 4.3Å; L318-K322 HydrophobicContact CD1-CG 4.2Å; L318-K322 HydrophobicContact CG-CD 4Å; L318-K322 HydrophobicContact CG-CG 4.34Å; L318-K322 WeakPolarHBondContact O-CB 3.43Å; L318-K322 VanDerWaalsContact O-CG 3.29Å; L318-K322 WeakPolarHBondContact O-CG 3.22Å; L318-K322 PolarHBondContact O-N 3.28Å
319A95.6Very high96Very high70 Ų7029.2 Ų29.258%0.57916%0.16SC*.Hα-helixtrans-61.5-45.2178.300000112S317 K322 H323S317-A319 PolarHBondContact O-N 3.11Å; A319-K322 PolarHBondContact O-N 3.07Å; A319-H323 WeakPolarHBondContact O-CB 3.14Å; A319-H323 PolarHBondContact O-N 3.42Å
320D95.9Very high96.3Very high75 Ų7527.8 Ų27.840%0.40115%0.15SC..Hα-helixtrans-67.7-40.9178.3-63.3-39.3000111.7S317 K322 H323 V324S317-D320 PolarHBondContact O-N 2.92Å; S317-D320 WeakPolarHBondContact OG-CB 3.47Å; S317-D320 PolarHBondContact OG-N 2.8Å; S317-D320 PolarHBondContact OG-OD2 2.78Å; D320-K322 VanDerWaalsContact C-N 3.34Å; D320-K322 PolarHBondContact O-N 2.92Å; D320-H323 PolarHBondContact O-N 2.88Å; D320-V324 WeakPolarHBondContact O-CG2 3.44Å; D320-V324 PolarHBondContact O-N 2.85Å
321I98.2Very high96.2Very high0 Ų030.3 Ų30.30%016%0.159CC..Hα-helixtrans-57.2-50.2174.8-64.2174.5000109.8Y220 F222 V241 F297 S317 L318 V324 F325 I381Y220-I321 HydrophobicContact CD1-CG2 4.19Å; Y220-I321 HydrophobicContact CE1-CG2 3.88Å; F222-I321 HydrophobicContact CZ-CD1 4.27Å; V241-I321 HydrophobicContact CG1-CG2 4.14Å; F297-I321 HydrophobicContact CD2-CD1 3.55Å; F297-I321 HydrophobicContact CE2-CD1 3.69Å; S317-I321 WeakPolarHBondContact O-CG1 3.48Å; S317-I321 PolarHBondContact O-N 3.08Å; L318-I321 PolarHBondContact O-N 3.11Å; I321-V324 PolarHBondContact O-N 3.37Å; I321-F325 HydrophobicContact CG2-CD2 3.86Å; I321-F325 HydrophobicContact CG2-CE2 3.59Å; I321-F325 WeakPolarHBondContact O-CD2 3.42Å; I321-F325 PolarHBondContact O-N 2.78Å; I321-I381 HydrophobicContact CB-CD1 4.32Å; I321-I381 HydrophobicContact CG1-CD1 3.88Å; I321-I381 HydrophobicContact CG1-CG1 4.42Å; I321-I381 HydrophobicContact CG1-CG2 4.11Å; I321-I381 HydrophobicContact CG2-CD1 4.18Å
322K97.2Very high95.9Very high73 Ų7330.4 Ų30.432%0.31716%0.161SC..Hα-helixtrans-61.2-47.1177.4-74175.564.7173.60111.7Y220 L318 A319 D320 V324 F325 D326Y220-K322 WeakPolarHBondContact OH-CG 3.41Å; L318-K322 HydrophobicContact CD1-CD 4.3Å; L318-K322 HydrophobicContact CD1-CG 4.2Å; L318-K322 HydrophobicContact CG-CD 4Å; L318-K322 HydrophobicContact CG-CG 4.34Å; L318-K322 WeakPolarHBondContact O-CB 3.43Å; L318-K322 VanDerWaalsContact O-CG 3.29Å; L318-K322 WeakPolarHBondContact O-CG 3.22Å; L318-K322 PolarHBondContact O-N 3.28Å; A319-K322 PolarHBondContact O-N 3.07Å; D320-K322 VanDerWaalsContact C-N 3.34Å; D320-K322 PolarHBondContact O-N 2.92Å; K322-V324 VanDerWaalsContact C-N 3.28Å; K322-V324 PolarHBondContact O-N 2.87Å; K322-F325 PolarHBondContact O-N 3.45Å; K322-F325 VanDerWaalsContact O-N 3.14Å; K322-D326 VanDerWaalsContact O-CB 3.29Å; K322-D326 WeakPolarHBondContact O-CB 3.32Å; K322-D326 PolarHBondContact O-N 3.05Å
323H97.2Very high95.6Very high101 Ų10133.1 Ų33.147%0.46817%0.173SC..Hα-helixtrans-56.1-42.8179.6177.8-89.7000112A319 D320 D326 H327A319-H323 WeakPolarHBondContact O-CB 3.14Å; A319-H323 PolarHBondContact O-N 3.42Å; D320-H323 PolarHBondContact O-N 2.88Å; H323-D326 PolarHBondContact O-N 2.8Å; H323-H327 AromaticContact CD2-ND1 3.48Å; H323-H327 PolarHBondContact CD2-ND1 3.35Å; H323-H327 AromaticContact CG-ND1 3.96Å; H323-H327 AromaticContact NE2-ND1 3.93Å; H323-H327 WeakPolarHBondContact O-CB 3.31Å; H323-H327 PolarHBondContact O-N 3.06Å; H323-H327 PolarHBondContact O-ND1 3.33Å; H323-H327 VanDerWaalsContact O-ND1 3.12Å
324V97.8Very high95Very high13 Ų1337.8 Ų37.88%0.07921%0.212CC..Hα-helixtrans-61.4-51.6175.4169.40000111.1T265 D320 I321 K322 D326 S328 M377 K379 I381T265-V324 HydrophobicContact CG2-CG1 4.1Å; D320-V324 WeakPolarHBondContact O-CG2 3.44Å; D320-V324 PolarHBondContact O-N 2.85Å; I321-V324 PolarHBondContact O-N 3.37Å; K322-V324 VanDerWaalsContact C-N 3.28Å; K322-V324 PolarHBondContact O-N 2.87Å; V324-D326 VanDerWaalsContact C-N 3.3Å; V324-D326 PolarHBondContact O-N 2.99Å; V324-S328 WeakPolarHBondContact O-CA 3.5Å; V324-S328 WeakPolarHBondContact O-CB 3.44Å; V324-S328 PolarHBondContact O-N 3.32Å; V324-M377 HydrophobicContact CG1-CB 4.39Å; V324-K379 HydrophobicContact CG1-CB 4.41Å; V324-K379 WeakPolarHBondContact CG1-O 3.44Å; V324-I381 HydrophobicContact CB-CG1 4.32Å; V324-I381 HydrophobicContact CG1-CG1 4.43Å; V324-I381 HydrophobicContact CG2-CG1 4.14Å
325F97.7Very high94.4Very high0 Ų039.7 Ų39.70%023%0.226CC..Hα-helixtrans-64.3-36.5-179.9-72.9-65.7000112.9Y220 V241 R243 L263 T265 I321 K322 R352 M377Y220-F325 HydrophobicContact CE1-CE2 4.36Å; V241-F325 HydrophobicContact CG1-CE2 4.17Å; V241-F325 HydrophobicContact CG1-CZ 4.31Å; V241-F325 WeakPolarHBondContact O-CZ 3.33Å; R243-F325 HydrophobicContact CB-CE2 4.25Å; R243-F325 HydrophobicContact CB-CZ 4.38Å; R243-F325 HydrophobicContact CG-CD1 4.18Å; R243-F325 HydrophobicContact CG-CD2 4.12Å; R243-F325 HydrophobicContact CG-CE1 4.21Å; R243-F325 HydrophobicContact CG-CE2 4.14Å; R243-F325 HydrophobicContact CG-CG 4.15Å; R243-F325 HydrophobicContact CG-CZ 4.18Å; R243-F325 VanDerWaalsContact NH1-CB 3.31Å; L263-F325 HydrophobicContact CB-CD1 3.88Å; L263-F325 HydrophobicContact CB-CE1 3.89Å; L263-F325 HydrophobicContact CD1-CD1 4.35Å; T265-F325 HydrophobicContact CG2-CE1 4.11Å; T265-F325 HydrophobicContact CG2-CE2 4.41Å; T265-F325 HydrophobicContact CG2-CZ 3.91Å; I321-F325 HydrophobicContact CG2-CD2 3.86Å; I321-F325 HydrophobicContact CG2-CE2 3.59Å; I321-F325 WeakPolarHBondContact O-CD2 3.42Å; I321-F325 PolarHBondContact O-N 2.78Å; K322-F325 PolarHBondContact O-N 3.45Å; K322-F325 VanDerWaalsContact O-N 3.14Å; F325-R352 PolarHBondContact O-NH2 2.8Å; F325-M377 HydrophobicContact CD1-CG 3.9Å; F325-M377 HydrophobicContact CD1-SD 4.27Å; F325-M377 HydrophobicContact CE1-CG 4.19Å
326D96Very high93.8Very high44 Ų4445.2 Ų45.224%0.23526%0.261CS..Hα-helixtrans-79.6-28.3-175-64.6-21.8000113R243 K322 H323 V324 R352R243-D326 IonicContact CZ-OD1 3.22Å; R243-D326 VanDerWaalsContact CZ-OD1 3.25Å; R243-D326 IonicContact NH1-OD1 2.69Å; R243-D326 PolarHBondContact NH1-OD1 3.12Å; R243-D326 IonicContact NH1-OD2 2.63Å; R243-D326 IonicContact NH2-OD1 3.53Å; R243-D326 PolarHBondContact NH2-OD1 3.24Å; K322-D326 VanDerWaalsContact O-CB 3.29Å; K322-D326 WeakPolarHBondContact O-CB 3.32Å; K322-D326 PolarHBondContact O-N 3.05Å; H323-D326 PolarHBondContact O-N 2.8Å; V324-D326 VanDerWaalsContact C-N 3.3Å; V324-D326 PolarHBondContact O-N 2.99Å; D326-R352 PolarHBondContact O-NE 3.29Å
327H95.6Very high93.1Very high122 Ų12249.7 Ų49.757%0.56530%0.298SS*.Hα-helixtrans-128.2-16.6-171.1-52.691.6000115.8H323H323-H327 AromaticContact CD2-ND1 3.48Å; H323-H327 PolarHBondContact CD2-ND1 3.35Å; H323-H327 AromaticContact CG-ND1 3.96Å; H323-H327 AromaticContact NE2-ND1 3.93Å; H323-H327 WeakPolarHBondContact O-CB 3.31Å; H323-H327 PolarHBondContact O-N 3.06Å; H323-H327 PolarHBondContact O-ND1 3.33Å; H323-H327 VanDerWaalsContact O-ND1 3.12Å
328S96.2Very high92.8Very high2 Ų254 Ų541%0.01432%0.317CS..PPolyproline II helixtrans-67.9148.3178.4-179.90000111.3V324 R352 M377 K379V324-S328 WeakPolarHBondContact O-CA 3.5Å; V324-S328 WeakPolarHBondContact O-CB 3.44Å; V324-S328 PolarHBondContact O-N 3.32Å; S328-R352 PolarHBondContact O-NH1 3.25Å; S328-R352 PolarHBondContact O-NH2 3.33Å; S328-M377 VanDerWaalsContact O-CE 3.25Å; S328-M377 WeakPolarHBondContact O-CE 3.44Å; S328-K379 WeakPolarHBondContact OG-CB 3.47Å; S328-K379 PolarHBondContact OG-N 2.88Å
329N96.5Very high92.3Very high43 Ų4355.7 Ų55.723%0.2333%0.334CS..PPolyproline II helixtrans-66.5167165.9-58.1-36.1000110.6L343 E378N329-L343 WeakPolarHBondContact CB-O 3.15Å; N329-E378 HydrophobicContact CB-CB 4.31Å; N329-E378 WeakPolarHBondContact CB-OE2 3.47Å; N329-E378 PolarHBondContact ND2-OE2 3.34Å; N329-E378 WeakPolarHBondContact O-CB 3.42Å; N329-E378 PolarHBondContact O-N 2.64Å
330F96.1Very high92.1Very high0 Ų054.1 Ų54.10%031%0.313CS..EExtended strand (participates in β ladder)trans-90.5154174-61.6-85000110.4L263 L343 T348 P353 F370 H374 M377L263-F330 HydrophobicContact CD1-CE1 4.07Å; L263-F330 HydrophobicContact CD2-CD1 4.37Å; L263-F330 HydrophobicContact CD2-CE1 3.67Å; F330-L343 HydrophobicContact CB-CD1 3.94Å; F330-L343 PolarHBondContact O-N 2.92Å; F330-T348 HydrophobicContact CD2-CG2 4.18Å; F330-T348 HydrophobicContact CE2-CG2 3.65Å; F330-P353 HydrophobicContact CE1-CB 4.39Å; F330-P353 HydrophobicContact CZ-CB 4.01Å; F330-P353 HydrophobicContact CZ-CG 4.3Å; F330-F370 HydrophobicContact CB-CZ 4.3Å; F330-F370 HydrophobicContact CD1-CE1 4.31Å; F330-F370 AromaticContact CD2-CE1 3.91Å; F330-F370 HydrophobicContact CD2-CE1 3.91Å; F330-F370 AromaticContact CD2-CZ 3.8Å; F330-F370 HydrophobicContact CD2-CZ 3.8Å; F330-F370 HydrophobicContact CE2-CE1 4.12Å; F330-F370 HydrophobicContact CE2-CZ 4.35Å; F330-F370 HydrophobicContact CG-CE1 4.02Å; F330-F370 HydrophobicContact CG-CZ 4.03Å; F330-F370 HydrophobicContact CZ-CE1 4.42Å; F330-H374 HydrophobicContact CB-CB 4.47Å; F330-H374 WeakPolarHBondContact CD1-O 3.13Å; F330-M377 HydrophobicContact CD1-CE 4.34Å; F330-M377 HydrophobicContact CD1-SD 3.88Å; F330-M377 HydrophobicContact CE1-CE 4.1Å; F330-M377 HydrophobicContact CE1-SD 3.71Å; F330-M377 HydrophobicContact CZ-CE 4.45Å
331K93.4Very high91.9Very high56 Ų5656.9 Ų56.924%0.24332%0.323CS..EExtended strand (participates in β ladder)trans-99.8135.7168.3-97171.7-179.2165.60109.7W340 Q341 L376 E378K331-W340 HydrophobicContact CB-CE3 4.12Å; K331-Q341 WeakPolarHBondContact CA-O 3.22Å; K331-L376 HydrophobicContact CB-CB 4.41Å; K331-L376 HydrophobicContact CB-CD2 4.12Å; K331-L376 HydrophobicContact CB-CG 4.15Å; K331-L376 HydrophobicContact CD-CD2 4.28Å; K331-L376 PolarHBondContact N-O 3.05Å; K331-E378 WeakPolarHBondContact CE-O 3.34Å; K331-E378 HydrophobicContact CG-CB 4.22Å; K331-E378 PolarHBondContact NZ-O 3.35Å
332G91.1Very high91.7Very high3 Ų359.2 Ų59.23%0.03134%0.34CS..EExtended strand (participates in β ladder)trans-147.8172.5178.600000112.2W340 Q341G332-W340 WeakPolarHBondContact O-CA 3.2Å; G332-Q341 PolarHBondContact N-O 2.85Å; G332-Q341 PolarHBondContact O-N 3.11Å
333Q88.5Confident91.5Very high56 Ų5656.7 Ų56.726%0.26233%0.33SS..  trans-128.4138.8170.1-60.5169.6-6200108.1S335 H338 W340Q333-S335 VanDerWaalsContact C-N 3.25Å; Q333-S335 WeakPolarHBondContact CB-O 3.32Å; Q333-S335 PolarHBondContact O-N 3.43Å; Q333-H338 WeakPolarHBondContact CG-O 3.45Å; Q333-H338 PolarHBondContact NE2-O 3.09Å; Q333-W340 VanDerWaalsContact CD-CE2 3.45Å; Q333-W340 HydrophobicContact CG-CB 4.24Å; Q333-W340 HydrophobicContact CG-CD2 3.64Å; Q333-W340 HydrophobicContact CG-CE3 4.25Å; Q333-W340 HydrophobicContact CG-CG 3.58Å; Q333-W340 VanDerWaalsContact NE2-NE1 3.15Å
334A83.9Confident91.2Very high98 Ų9854.1 Ų54.181%0.8132%0.323SS*.SBendtrans-63.3-34.3173.900000112.1
335S83.4Confident90.7Very high41 Ų4157.8 Ų57.829%0.28735%0.347SS..SBendtrans-149.9164.6168.581.40000109.7Q333 A337 H338Q333-S335 VanDerWaalsContact C-N 3.25Å; Q333-S335 WeakPolarHBondContact CB-O 3.32Å; Q333-S335 PolarHBondContact O-N 3.43Å; S335-A337 PolarHBondContact O-N 2.85Å; S335-A337 PolarHBondContact OG-N 3.14Å; S335-H338 PolarHBondContact O-N 2.85Å; S335-H338 PolarHBondContact OG-ND1 3.03Å
336P81.8Confident90.4Very high118 Ų11867.4 Ų67.477%0.76639%0.389SS*.THydrogen-bonded Turntrans-55.4-19.5178.9-26.635.5000115.1
337A82.7Confident90.1Very high94 Ų9470.5 Ų70.578%0.77740%0.402SS*.THydrogen-bonded Turntrans-86.5-14178.600000114.2S335S335-A337 PolarHBondContact O-N 2.85Å; S335-A337 PolarHBondContact OG-N 3.14Å
338H86.8Confident89.9Confident106 Ų10665.9 Ų65.949%0.49138%0.382SS..SBendtrans-87.5153.7-179-72.578000111.4Q333 S335Q333-H338 WeakPolarHBondContact CG-O 3.45Å; Q333-H338 PolarHBondContact NE2-O 3.09Å; S335-H338 PolarHBondContact O-N 2.85Å; S335-H338 PolarHBondContact OG-ND1 3.03Å
339A87.4Confident89.7Confident55 Ų5567 Ų6746%0.45539%0.389SS..PPolyproline II helixtrans-63.4151.517100000111.2Q341A339-Q341 PolarHBondContact O-N 2.93Å
340W90.5Very high89.2Confident36 Ų3671.8 Ų71.814%0.13642%0.42CS..PPolyproline II helixtrans-69.1127.1171.8-70.974.8000109.8V228 E229 K331 G332 Q333 L376V228-W340 HydrophobicContact CB-CZ2 3.91Å; V228-W340 HydrophobicContact CG2-CH2 3.9Å; V228-W340 HydrophobicContact CG2-CZ2 3.47Å; V228-W340 VanDerWaalsContact CG2-CZ2 3.47Å; V228-W340 PolarHBondContact O-NE1 3.14Å; E229-W340 HydrophobicContact CB-CB 3.99Å; E229-W340 HydrophobicContact CB-CD2 3.97Å; E229-W340 HydrophobicContact CB-CG 3.69Å; K331-W340 HydrophobicContact CB-CE3 4.12Å; G332-W340 WeakPolarHBondContact O-CA 3.2Å; Q333-W340 VanDerWaalsContact CD-CE2 3.45Å; Q333-W340 HydrophobicContact CG-CB 4.24Å; Q333-W340 HydrophobicContact CG-CD2 3.64Å; Q333-W340 HydrophobicContact CG-CE3 4.25Å; Q333-W340 HydrophobicContact CG-CG 3.58Å; Q333-W340 VanDerWaalsContact NE2-NE1 3.15Å; W340-L376 HydrophobicContact CE3-CD2 4.16Å; W340-L376 HydrophobicContact CZ3-CB 4.39Å; W340-L376 HydrophobicContact CZ3-CD2 4.09Å
341Q92Very high88.9Confident134 Ų13474.6 Ų74.663%0.62644%0.438SS*.EExtended strand (participates in β ladder)trans-126.9156.8-178-68.2-178.7-10.500110.7K331 G332 A339K331-Q341 WeakPolarHBondContact CA-O 3.22Å; G332-Q341 PolarHBondContact N-O 2.85Å; G332-Q341 PolarHBondContact O-N 3.11Å; A339-Q341 PolarHBondContact O-N 2.93Å
342S93.7Very high88.9Confident49 Ų4973.9 Ų73.934%0.34343%0.433SS..EExtended strand (participates in β ladder)trans-69.4127.8169.4-174.40000109.4E378S342-E378 WeakPolarHBondContact CB-OE1 3.46Å; S342-E378 PolarHBondContact OG-OE1 3Å; S342-E378 PolarHBondContact OG-OE2 2.94Å
343L93.1Very high88.9Confident20 Ų2074.1 Ų74.111%0.10543%0.434CS..PPolyproline II helixtrans-77.3144.1174.8-68.4176.5000110.5N329 F330 F370 H374N329-L343 WeakPolarHBondContact CB-O 3.15Å; F330-L343 HydrophobicContact CB-CD1 3.94Å; F330-L343 PolarHBondContact O-N 2.92Å; L343-F370 HydrophobicContact CD1-CE2 4.1Å; L343-F370 HydrophobicContact CD1-CZ 4.04Å; L343-H374 WeakPolarHBondContact CD1-CD2 3.39Å
344S90.9Very high89.1Confident46 Ų4671.6 Ų71.632%0.32242%0.423SS..PPolyproline II helixtrans-68.7148.3174.274.10000110.5K346 E347S344-K346 PolarHBondContact O-N 2.88Å; S344-E347 VanDerWaalsContact CB-OE2 3.31Å; S344-E347 WeakPolarHBondContact CB-OE2 3.26Å; S344-E347 PolarHBondContact N-OE2 2.88Å; S344-E347 PolarHBondContact O-N 2.59Å; S344-E347 WeakPolarHBondContact OG-CG 3.45Å; S344-E347 PolarHBondContact OG-OE2 2.94Å
345P88.3Confident89.5Confident91 Ų9171 Ų7159%0.59140%0.404SS*.THydrogen-bonded Turntrans-56.2-22.9175.3-27.234.1000114E347 T348P345-E347 VanDerWaalsContact C-N 3.33Å; P345-T348 PolarHBondContact O-N 2.73Å
346K89.9Confident90.1Very high202 Ų20271.5 Ų71.588%0.87841%0.407SS*.THydrogen-bonded Turntrans-73.3-22.9179.3-64.4-179179.7178.60113.5S344S344-K346 PolarHBondContact O-N 2.88Å
347E89.7Confident90.7Very high109 Ų10968 Ų6851%0.50938%0.383SS..THydrogen-bonded Turntrans-85.8-14.8177.2-67.6164.685.200112.1S344 P345 F370S344-E347 VanDerWaalsContact CB-OE2 3.31Å; S344-E347 WeakPolarHBondContact CB-OE2 3.26Å; S344-E347 PolarHBondContact N-OE2 2.88Å; S344-E347 PolarHBondContact O-N 2.59Å; S344-E347 WeakPolarHBondContact OG-CG 3.45Å; S344-E347 PolarHBondContact OG-OE2 2.94Å; P345-E347 VanDerWaalsContact C-N 3.33Å; E347-F370 WeakPolarHBondContact O-CE2 3.39Å
348T92Very high91.1Very high24 Ų2475.6 Ų75.615%0.14739%0.391CS..SBendtrans-73.9133.4176.8-59.40000109.4F330 P345F330-T348 HydrophobicContact CD2-CG2 4.18Å; F330-T348 HydrophobicContact CE2-CG2 3.65Å; P345-T348 PolarHBondContact O-N 2.73Å
349P91.7Very high91.4Very high25 Ų2573.3 Ų73.316%0.16238%0.383CS..  trans-58155.6177.1-21.930.5000113.2V351 P353 D367 F370P349-V351 VanDerWaalsContact C-N 3.34Å; P349-V351 CarbonylContact O-C 3.59Å; P349-V351 PolarHBondContact O-N 2.9Å; P349-P353 HydrophobicContact CG-CG 4.11Å; P349-D367 WeakPolarHBondContact CB-OD1 3.43Å; P349-F370 HydrophobicContact CG-CB 3.69Å; P349-F370 HydrophobicContact CG-CD1 4.04Å; P349-F370 HydrophobicContact CG-CD2 3.91Å; P349-F370 HydrophobicContact CG-CG 3.6Å
350T87.1Confident91.8Very high144 Ų14470.8 Ų70.888%0.88336%0.362SS*.SBendtrans-60.2-43-178.754.70000112.2R352T350-R352 PolarHBondContact O-N 2.91Å
351V89Confident92Very high60 Ų6073.3 Ų73.336%0.36437%0.374SS..SBendtrans-80.8106.2165.1-178.90000107.1P349 P353 V357 L363P349-V351 VanDerWaalsContact C-N 3.34Å; P349-V351 CarbonylContact O-C 3.59Å; P349-V351 PolarHBondContact O-N 2.9Å; V351-P353 VanDerWaalsContact O-CD 3.26Å; V351-P353 WeakPolarHBondContact O-CD 3.25Å; V351-V357 HydrophobicContact CG1-CG1 4.01Å; V351-L363 HydrophobicContact CG1-CD2 4Å
352R92.9Very high92.1Very high40 Ų4073.8 Ų73.815%0.15138%0.38CS..  trans-60.5121.9-176.8-178.217417280.10.8110.5F325 D326 S328 T350 Q355F325-R352 PolarHBondContact O-NH2 2.8Å; D326-R352 PolarHBondContact O-NE 3.29Å; S328-R352 PolarHBondContact O-NH1 3.25Å; S328-R352 PolarHBondContact O-NH2 3.33Å; T350-R352 PolarHBondContact O-N 2.91Å; R352-Q355 HydrophobicContact CB-CG 4.36Å; R352-Q355 PolarHBondContact O-N 2.91Å
353P92.4Very high92.1Very high8 Ų872.8 Ų72.85%0.05237%0.371CS..THydrogen-bonded Turntrans-54.2144.3175.9-3038.3000113.2F330 P349 V351 Q355 F370 V371F330-P353 HydrophobicContact CE1-CB 4.39Å; F330-P353 HydrophobicContact CZ-CB 4.01Å; F330-P353 HydrophobicContact CZ-CG 4.3Å; P349-P353 HydrophobicContact CG-CG 4.11Å; V351-P353 VanDerWaalsContact O-CD 3.26Å; V351-P353 WeakPolarHBondContact O-CD 3.25Å; P353-Q355 VanDerWaalsContact C-N 3.34Å; P353-F370 HydrophobicContact CB-CD1 4.23Å; P353-F370 HydrophobicContact CB-CE1 4.38Å; P353-F370 HydrophobicContact CG-CD1 3.43Å; P353-F370 VanDerWaalsContact CG-CD1 3.43Å; P353-F370 HydrophobicContact CG-CE1 3.66Å; P353-F370 HydrophobicContact CG-CG 4.41Å; P353-V371 HydrophobicContact CB-CG2 3.91Å; P353-V371 HydrophobicContact CG-CG2 4.39Å
354G92.1Very high92.2Very high3 Ų374.4 Ų74.43%0.03138%0.384CS..THydrogen-bonded Turntrans82.20.8178.400000116.2R243R243-G354 PolarHBondContact NH2-O 3.41Å
355Q93Very high92.3Very high87 Ų8776.1 Ų76.141%0.40739%0.389SS..SBendtrans-83.8146.4168.2-67.5-174.9-2700111.1R352 P353 V357R352-Q355 HydrophobicContact CB-CG 4.36Å; R352-Q355 PolarHBondContact O-N 2.91Å; P353-Q355 VanDerWaalsContact C-N 3.34Å; Q355-V357 PolarHBondContact O-N 3.32Å
356C95Very high92.5Very high51 Ų5175.2 Ų75.235%0.34539%0.389SS..  trans-65121.7168.9-71.90000111Y218 C245Y218-C356 VanDerWaalsContact CE1-SG 3.59Å; Y218-C356 VanDerWaalsContact CZ-SG 3.54Å; Y218-C356 PolarHBondContact OH-N 2.96Å; Y218-C356 VanDerWaalsContact OH-N 3.14Å; C245-C356 HydrophobicContact CB-CB 4.13Å; C245-C356 WeakPolarHBondContact CB-SG 3.31Å; C245-C356 WeakPolarHBondContact SG-CA 3.45Å; C245-C356 WeakPolarHBondContact SG-CB 3.49Å; C245-C356 CovalentContact SG-SG 2.03Å; C245-C356 PolarHBondContact SG-SG 2.53Å
357V94.7Very high92.7Very high43 Ų4366.6 Ų66.626%0.26135%0.353SS..  trans-109.6159.6172.7-63.90000110.6V351 Q355 D359 L363V351-V357 HydrophobicContact CG1-CG1 4.01Å; Q355-V357 PolarHBondContact O-N 3.32Å; V357-D359 PolarHBondContact O-N 2.82Å; V357-L363 HydrophobicContact CG1-CD2 4.39Å; V357-L363 HydrophobicContact CG2-CD1 4.48Å; V357-L363 HydrophobicContact CG2-CD2 4.48Å; V357-L363 HydrophobicContact CG2-CG 4.45Å
358R90.3Very high92.9Very high255 Ų25561.4 Ų61.496%0.96233%0.328SS*.SBendtrans-60.5-43.2-179-68.5-176.4-177.8170.70.8112.8
359D93.9Very high93Very high58 Ų5865.6 Ų65.631%0.3135%0.346SS..  trans-145.1112.7174.1-178.10000109V249 V357 K361 L362V249-D359 WeakPolarHBondContact CG2-OD1 3.49Å; V357-D359 PolarHBondContact O-N 2.82Å; D359-K361 PolarHBondContact O-N 2.82Å; D359-K361 VanDerWaalsContact OD1-CB 3.29Å; D359-K361 WeakPolarHBondContact OD1-CB 3.46Å; D359-K361 PolarHBondContact OD1-N 2.86Å; D359-L362 HydrophobicContact CB-CD1 3.99Å; D359-L362 HydrophobicContact CB-CG 3.99Å; D359-L362 WeakPolarHBondContact O-CB 3.45Å; D359-L362 PolarHBondContact O-N 3.45Å; D359-L362 VanDerWaalsContact O-N 3.13Å
360S95.2Very high93.2Very high2 Ų265.2 Ų65.21%0.01434%0.342CS..G310 helixtrans-67.4-15.618055.80000113.3D248 V249 G250 T260 L362 L363D248-S360 PolarHBondContact OD1-OG 3.19Å; V249-S360 WeakPolarHBondContact CG2-OG 3.34Å; V249-S360 PolarHBondContact N-OG 3.08Å; G250-S360 PolarHBondContact N-OG 2.91Å; G250-S360 VanDerWaalsContact N-OG 3.1Å; G250-S360 CarbonylContact O-C 3.29Å; G250-S360 VanDerWaalsContact O-C 3.29Å; G250-S360 WeakPolarHBondContact O-CB 3.43Å; G250-S360 PolarHBondContact O-OG 2.78Å; T260-S360 VanDerWaalsContact OG1-CB 3.22Å; T260-S360 WeakPolarHBondContact OG1-CB 3.27Å; S360-L362 PolarHBondContact O-N 3.18Å; S360-L363 WeakPolarHBondContact O-CB 3.24Å; S360-L363 WeakPolarHBondContact O-CG 3.42Å; S360-L363 PolarHBondContact O-N 3.09Å
361K94.9Very high93.5Very high89 Ų8958.6 Ų58.639%0.38730%0.301SS..G310 helixtrans-72.1-14.5173.1-65.3177.8179.4175.60113V249 G250 R252 D359V249-K361 HydrophobicContact CG2-CG 4.23Å; G250-K361 WeakPolarHBondContact O-CG 3.26Å; G250-K361 PolarHBondContact O-N 2.85Å; R252-K361 HydrophobicContact CB-CB 4.28Å; R252-K361 WeakPolarHBondContact CB-O 3.49Å; D359-K361 PolarHBondContact O-N 2.82Å; D359-K361 VanDerWaalsContact OD1-CB 3.29Å; D359-K361 WeakPolarHBondContact OD1-CB 3.46Å; D359-K361 PolarHBondContact OD1-N 2.86Å
362L94.6Very high93.7Very high144 Ų14459.5 Ų59.575%0.75430%0.3SS*.G310 helixtrans-86.7-6.3176.1-59.2179.2000113.2D359 S360D359-L362 HydrophobicContact CB-CD1 3.99Å; D359-L362 HydrophobicContact CB-CG 3.99Å; D359-L362 WeakPolarHBondContact O-CB 3.45Å; D359-L362 PolarHBondContact O-N 3.45Å; D359-L362 VanDerWaalsContact O-N 3.13Å; S360-L362 PolarHBondContact O-N 3.18Å
363L94.2Very high93.7Very high28 Ų2858.8 Ų58.815%0.14730%0.301CS..SBendtrans-63.6142.4173.4-66173.6000110.4T260 V351 V357 S360 D367 L368T260-L363 HydrophobicContact CG2-CD1 4.38Å; V351-L363 HydrophobicContact CG1-CD2 4Å; V357-L363 HydrophobicContact CG1-CD2 4.39Å; V357-L363 HydrophobicContact CG2-CD1 4.48Å; V357-L363 HydrophobicContact CG2-CD2 4.48Å; V357-L363 HydrophobicContact CG2-CG 4.45Å; S360-L363 WeakPolarHBondContact O-CB 3.24Å; S360-L363 WeakPolarHBondContact O-CG 3.42Å; S360-L363 PolarHBondContact O-N 3.09Å; L363-D367 HydrophobicContact CB-CB 4.49Å; L363-L368 HydrophobicContact CB-CD2 3.98Å; L363-L368 HydrophobicContact CB-CG 4.06Å; L363-L368 HydrophobicContact CD1-CD2 3.98Å
364S94.4Very high93.8Very high54 Ų5459.9 Ų59.938%0.37831%0.305SS..  trans-72.6156.2178.974.90000111.3A366 D367 L368S364-A366 PolarHBondContact O-N 2.89Å; S364-D367 WeakPolarHBondContact CB-OD2 3.21Å; S364-D367 PolarHBondContact N-OD2 3.2Å; S364-D367 VanDerWaalsContact N-OD2 3.1Å; S364-D367 PolarHBondContact O-N 2.69Å; S364-D367 VanDerWaalsContact O-N 3.09Å; S364-D367 PolarHBondContact OG-N 3.21Å; S364-D367 PolarHBondContact OG-OD1 2.84Å; S364-D367 PolarHBondContact OG-OD2 2.6Å; S364-L368 WeakPolarHBondContact O-CG 3.34Å; S364-L368 PolarHBondContact O-N 2.92Å
365D93.1Very high94Very high82 Ų8259.9 Ų59.944%0.43930%0.304SS..Hα-helixtrans-61.3-26.3176.4-73.8-24.1000111.9H369D365-H369 VanDerWaalsContact O-CB 3.28Å; D365-H369 WeakPolarHBondContact O-CB 3.42Å; D365-H369 PolarHBondContact O-N 3.12Å
366A92.8Very high94.2Very high71 Ų7155.8 Ų55.859%0.58729%0.285SS*.Hα-helixtrans-69-44.1173.100000112.2S364 L368 H369 F370S364-A366 PolarHBondContact O-N 2.89Å; A366-L368 VanDerWaalsContact C-N 3.35Å; A366-H369 PolarHBondContact O-N 3.43Å; A366-F370 PolarHBondContact O-N 2.85Å
367D93.7Very high94.3Very high22 Ų2253.5 Ų53.512%0.11827%0.27CS..Hα-helixtrans-62.9-44.4175.5-55.2-40.5000110.5P349 L363 S364 H369 F370 V371P349-D367 WeakPolarHBondContact CB-OD1 3.43Å; L363-D367 HydrophobicContact CB-CB 4.49Å; S364-D367 WeakPolarHBondContact CB-OD2 3.21Å; S364-D367 PolarHBondContact N-OD2 3.2Å; S364-D367 VanDerWaalsContact N-OD2 3.1Å; S364-D367 PolarHBondContact O-N 2.69Å; S364-D367 VanDerWaalsContact O-N 3.09Å; S364-D367 PolarHBondContact OG-N 3.21Å; S364-D367 PolarHBondContact OG-OD1 2.84Å; S364-D367 PolarHBondContact OG-OD2 2.6Å; D367-H369 VanDerWaalsContact C-N 3.34Å; D367-H369 PolarHBondContact O-N 3.27Å; D367-F370 WeakPolarHBondContact O-CB 3.28Å; D367-F370 PolarHBondContact O-N 3.08Å; D367-V371 WeakPolarHBondContact O-CG2 3.49Å; D367-V371 PolarHBondContact O-N 2.8Å
368L94.9Very high94.3Very high0 Ų054.5 Ų54.50%027%0.271CS..Hα-helixtrans-65.7-36.3178.4-65.2173.8000112L254 L255 T260 L363 S364 A366 V371 K372L254-L368 HydrophobicContact CB-CB 4.17Å; L254-L368 HydrophobicContact CB-CD1 4.14Å; L254-L368 HydrophobicContact CD2-CB 3.83Å; L254-L368 HydrophobicContact CG-CB 4.28Å; L255-L368 HydrophobicContact CD1-CB 4.47Å; L255-L368 HydrophobicContact CD1-CD2 4.22Å; T260-L368 HydrophobicContact CG2-CD2 3.47Å; T260-L368 VanDerWaalsContact CG2-CD2 3.47Å; L363-L368 HydrophobicContact CB-CD2 3.98Å; L363-L368 HydrophobicContact CB-CG 4.06Å; L363-L368 HydrophobicContact CD1-CD2 3.98Å; S364-L368 WeakPolarHBondContact O-CG 3.34Å; S364-L368 PolarHBondContact O-N 2.92Å; A366-L368 VanDerWaalsContact C-N 3.35Å; L368-V371 PolarHBondContact O-N 3.25Å; L368-K372 WeakPolarHBondContact O-CB 3.02Å; L368-K372 PolarHBondContact O-N 3.41Å
369H94.1Very high94.6Very high112 Ų11247.9 Ų47.952%0.51925%0.249SC..Hα-helixtrans-64.8-40.7173.1-178.8-85.9000111.5L254 D365 A366 D367 K372 T373L254-H369 HydrophobicContact CD2-CB 4.28Å; D365-H369 VanDerWaalsContact O-CB 3.28Å; D365-H369 WeakPolarHBondContact O-CB 3.42Å; D365-H369 PolarHBondContact O-N 3.12Å; A366-H369 PolarHBondContact O-N 3.43Å; D367-H369 VanDerWaalsContact C-N 3.34Å; D367-H369 PolarHBondContact O-N 3.27Å; H369-K372 PolarHBondContact O-N 2.88Å; H369-T373 PolarHBondContact O-N 2.78Å; H369-T373 PolarHBondContact O-OG1 2.76Å
370F94.6Very high94.7Very high17 Ų1747.6 Ų47.68%0.07525%0.252CS..Hα-helixtrans-61-51.4174.3-173.6-79.5000111.1F330 L343 E347 P349 P353 A366 D367 K372 T373 H374F330-F370 HydrophobicContact CB-CZ 4.3Å; F330-F370 HydrophobicContact CD1-CE1 4.31Å; F330-F370 AromaticContact CD2-CE1 3.91Å; F330-F370 HydrophobicContact CD2-CE1 3.91Å; F330-F370 AromaticContact CD2-CZ 3.8Å; F330-F370 HydrophobicContact CD2-CZ 3.8Å; F330-F370 HydrophobicContact CE2-CE1 4.12Å; F330-F370 HydrophobicContact CE2-CZ 4.35Å; F330-F370 HydrophobicContact CG-CE1 4.02Å; F330-F370 HydrophobicContact CG-CZ 4.03Å; F330-F370 HydrophobicContact CZ-CE1 4.42Å; L343-F370 HydrophobicContact CD1-CE2 4.1Å; L343-F370 HydrophobicContact CD1-CZ 4.04Å; E347-F370 WeakPolarHBondContact O-CE2 3.39Å; P349-F370 HydrophobicContact CG-CB 3.69Å; P349-F370 HydrophobicContact CG-CD1 4.04Å; P349-F370 HydrophobicContact CG-CD2 3.91Å; P349-F370 HydrophobicContact CG-CG 3.6Å; P353-F370 HydrophobicContact CB-CD1 4.23Å; P353-F370 HydrophobicContact CB-CE1 4.38Å; P353-F370 HydrophobicContact CG-CD1 3.43Å; P353-F370 VanDerWaalsContact CG-CD1 3.43Å; P353-F370 HydrophobicContact CG-CE1 3.66Å; P353-F370 HydrophobicContact CG-CG 4.41Å; A366-F370 PolarHBondContact O-N 2.85Å; D367-F370 WeakPolarHBondContact O-CB 3.28Å; D367-F370 PolarHBondContact O-N 3.08Å; F370-K372 VanDerWaalsContact C-N 3.27Å; F370-K372 PolarHBondContact O-N 2.88Å; F370-T373 PolarHBondContact O-N 2.79Å; F370-T373 PolarHBondContact O-OG1 3.47Å; F370-H374 HydrophobicContact CD1-CB 3.97Å; F370-H374 AromaticContact CD2-ND1 3.77Å; F370-H374 HydrophobicContact CE1-CB 3.59Å; F370-H374 HydrophobicContact CE2-CB 4.37Å; F370-H374 AromaticContact CE2-ND1 3.87Å; F370-H374 HydrophobicContact CZ-CB 3.83Å; F370-H374 WeakPolarHBondContact O-CB 3.36Å; F370-H374 PolarHBondContact O-N 3.06Å; F370-H374 PolarHBondContact O-ND1 2.98Å
371V93.9Very high94.8Very high5 Ų547.6 Ų47.63%0.0325%0.252CS..Hα-helixtrans-53.1-46.6176.7170.10000111W202 L255 T260 P353 D367 L368 T373W202-V371 HydrophobicContact CZ2-CG1 4.39Å; L255-V371 HydrophobicContact CD1-CB 4.28Å; L255-V371 HydrophobicContact CD1-CG1 3.91Å; T260-V371 VanDerWaalsContact O-CG1 3.29Å; T260-V371 WeakPolarHBondContact O-CG1 3.38Å; T260-V371 WeakPolarHBondContact O-CG2 3.39Å; P353-V371 HydrophobicContact CB-CG2 3.91Å; P353-V371 HydrophobicContact CG-CG2 4.39Å; D367-V371 WeakPolarHBondContact O-CG2 3.49Å; D367-V371 PolarHBondContact O-N 2.8Å; L368-V371 PolarHBondContact O-N 3.25Å; V371-T373 PolarHBondContact O-N 2.85Å
372K93.8Very high94.7Very high78 Ų7845.6 Ų45.634%0.33925%0.252SS..Hα-helixtrans-58.5-33.7179.1-176.2176.3178.7-174.50112.9I196 W202 L254 L255 L368 H369 F370I196-K372 HydrophobicContact CD1-CD 4.37Å; I196-K372 HydrophobicContact CD1-CG 3.84Å; W202-K372 PolarHBondContact NE1-O 2.97Å; L254-K372 HydrophobicContact CD1-CD 4.49Å; L255-K372 HydrophobicContact CD2-CB 4.27Å; L255-K372 HydrophobicContact CD2-CD 4.4Å; L255-K372 HydrophobicContact CD2-CG 4.36Å; L368-K372 WeakPolarHBondContact O-CB 3.02Å; L368-K372 PolarHBondContact O-N 3.41Å; H369-K372 PolarHBondContact O-N 2.88Å; F370-K372 VanDerWaalsContact C-N 3.27Å; F370-K372 PolarHBondContact O-N 2.88Å
373T93Very high94.6Very high26 Ų2639.1 Ų39.116%0.1622%0.219CC..Hα-helixtrans-102.8-17.1-170.949.80000114.4H369 F370 V371H369-T373 PolarHBondContact O-N 2.78Å; H369-T373 PolarHBondContact O-OG1 2.76Å; F370-T373 PolarHBondContact O-N 2.79Å; F370-T373 PolarHBondContact O-OG1 3.47Å; V371-T373 PolarHBondContact O-N 2.85Å
374H94.9Very high94.4Very high31 Ų3138.8 Ų38.814%0.14422%0.217CC..  trans-135.464.3-171-60.597.4000112.8F330 L343 F370F330-H374 HydrophobicContact CB-CB 4.47Å; F330-H374 WeakPolarHBondContact CD1-O 3.13Å; L343-H374 WeakPolarHBondContact CD1-CD2 3.39Å; F370-H374 HydrophobicContact CD1-CB 3.97Å; F370-H374 AromaticContact CD2-ND1 3.77Å; F370-H374 HydrophobicContact CE1-CB 3.59Å; F370-H374 HydrophobicContact CE2-CB 4.37Å; F370-H374 AromaticContact CE2-ND1 3.87Å; F370-H374 HydrophobicContact CZ-CB 3.83Å; F370-H374 WeakPolarHBondContact O-CB 3.36Å; F370-H374 PolarHBondContact O-N 3.06Å; F370-H374 PolarHBondContact O-ND1 2.98Å
375A95.2Very high93.7Very high2 Ų239.3 Ų39.32%0.01722%0.219CC..  trans-86.2-12.1178.700000114.4F262 L263 K264F262-A375 HydrophobicContact CD1-CB 4.09Å; F262-A375 HydrophobicContact CE1-CB 4.17Å; L263-A375 WeakPolarHBondContact CA-O 2.96Å; K264-A375 PolarHBondContact N-O 2.84Å
376L96.7Very high92.5Very high2 Ų236 Ų361%0.0120%0.202CC..EExtended strand (participates in β ladder)trans-96.9130.4-173-178.563.2000111.7E229 K264 K331 W340E229-L376 HydrophobicContact CB-CD2 4.11Å; E229-L376 HydrophobicContact CG-CD2 4.29Å; K264-L376 HydrophobicContact CG-CD1 4.1Å; K264-L376 WeakPolarHBondContact O-CA 3.09Å; K331-L376 HydrophobicContact CB-CB 4.41Å; K331-L376 HydrophobicContact CB-CD2 4.12Å; K331-L376 HydrophobicContact CB-CG 4.15Å; K331-L376 HydrophobicContact CD-CD2 4.28Å; K331-L376 PolarHBondContact N-O 3.05Å; W340-L376 HydrophobicContact CE3-CD2 4.16Å; W340-L376 HydrophobicContact CZ3-CB 4.39Å; W340-L376 HydrophobicContact CZ3-CD2 4.09Å
377M97Very high90.8Very high3 Ų336 Ų362%0.01519%0.19CC..EExtended strand (participates in β ladder)trans-80.2150.8173.4-49.3-53.7-64.900112.3L263 K264 V324 F325 S328 F330L263-M377 HydrophobicContact CB-SD 4.42Å; L263-M377 HydrophobicContact CD1-SD 3.91Å; L263-M377 HydrophobicContact CD2-SD 4.41Å; K264-M377 WeakPolarHBondContact O-CG 3.2Å; K264-M377 PolarHBondContact O-N 2.63Å; V324-M377 HydrophobicContact CG1-CB 4.39Å; F325-M377 HydrophobicContact CD1-CG 3.9Å; F325-M377 HydrophobicContact CD1-SD 4.27Å; F325-M377 HydrophobicContact CE1-CG 4.19Å; S328-M377 VanDerWaalsContact O-CE 3.25Å; S328-M377 WeakPolarHBondContact O-CE 3.44Å; F330-M377 HydrophobicContact CD1-CE 4.34Å; F330-M377 HydrophobicContact CD1-SD 3.88Å; F330-M377 HydrophobicContact CE1-CE 4.1Å; F330-M377 HydrophobicContact CE1-SD 3.71Å; F330-M377 HydrophobicContact CZ-CE 4.45Å
378E95.5Very high88.8Confident63 Ų6337.2 Ų37.229%0.29420%0.203SC..SBendtrans-66.8-58.4175.1179.1-166.9-163.700112.8N329 K331 S342N329-E378 HydrophobicContact CB-CB 4.31Å; N329-E378 WeakPolarHBondContact CB-OE2 3.47Å; N329-E378 PolarHBondContact ND2-OE2 3.34Å; N329-E378 WeakPolarHBondContact O-CB 3.42Å; N329-E378 PolarHBondContact O-N 2.64Å; K331-E378 WeakPolarHBondContact CE-O 3.34Å; K331-E378 HydrophobicContact CG-CB 4.22Å; K331-E378 PolarHBondContact NZ-O 3.35Å; S342-E378 WeakPolarHBondContact CB-OE1 3.46Å; S342-E378 PolarHBondContact OG-OE1 3Å; S342-E378 PolarHBondContact OG-OE2 2.94Å
379K96.4Very high86.7Confident116 Ų11639.6 Ų39.650%0.50423%0.228SC..SBendtrans-76.7131.3-174.5-68.3-174.8175.7-177.80110.4T265 V324 S328T265-K379 PolarHBondContact OG1-O 2.63Å; V324-K379 HydrophobicContact CG1-CB 4.41Å; V324-K379 WeakPolarHBondContact CG1-O 3.44Å; S328-K379 WeakPolarHBondContact OG-CB 3.47Å; S328-K379 PolarHBondContact OG-N 2.88Å
380S95.7Very high85Confident52 Ų5242.3 Ų42.336%0.36425%0.246SC..PPolyproline II helixtrans-78.7149.716856.80000111.2R266R266-S380 CarbonylContact O-C 3.55Å; R266-S380 WeakPolarHBondContact O-CA 3.34Å; R266-S380 WeakPolarHBondContact O-CB 3.45Å
381I97.2Very high83.5Confident2 Ų247.2 Ų47.21%0.0127%0.269CS..BIsolated β-bridgetrans-76.2123.6169.4-58.9153.9000108.2V241 T265 R266 I267 N268 Y316 I321 V324V241-I381 HydrophobicContact CB-CD1 4.02Å; V241-I381 HydrophobicContact CG2-CD1 3.95Å; T265-I381 HydrophobicContact CG2-CD1 3.33Å; T265-I381 HydrophobicContact CG2-CG1 3.79Å; R266-I381 PolarHBondContact O-N 3.28Å; I267-I381 HydrophobicContact CB-CB 4.46Å; I267-I381 HydrophobicContact CG1-CB 4.21Å; I267-I381 HydrophobicContact CG1-CG2 4.37Å; N268-I381 PolarHBondContact N-O 2.82Å; Y316-I381 HydrophobicContact CD1-CG2 3.67Å; Y316-I381 HydrophobicContact CE1-CG2 4.3Å; Y316-I381 HydrophobicContact CG-CG2 4.45Å; I321-I381 HydrophobicContact CB-CD1 4.32Å; I321-I381 HydrophobicContact CG1-CD1 3.88Å; I321-I381 HydrophobicContact CG1-CG1 4.42Å; I321-I381 HydrophobicContact CG1-CG2 4.11Å; I321-I381 HydrophobicContact CG2-CD1 4.18Å; V324-I381 HydrophobicContact CB-CG1 4.32Å; V324-I381 HydrophobicContact CG1-CG1 4.43Å; V324-I381 HydrophobicContact CG2-CG1 4.14Å
382A93.7Very high82.6Confident48 Ų4849.7 Ų49.740%0.39728%0.284SS..PPolyproline II helixtrans-94.1154.5174.300000110.6Y316 V392Y316-A382 WeakPolarHBondContact CD1-O 3.4Å; A382-V392 HydrophobicContact CB-CG1 4.34Å
383P93.1Very high82.3Confident7 Ų746.5 Ų46.55%0.04527%0.274CS..PPolyproline II helixtrans-69158.9174.431.3-33.3000110.5N268 C314 I315 Y316 V392N268-P383 WeakPolarHBondContact O-CD 3.39Å; C314-P383 HydrophobicContact CB-CB 3.99Å; I315-P383 CarbonylContact O-C 3.55Å; I315-P383 VanDerWaalsContact O-CA 3.27Å; I315-P383 WeakPolarHBondContact O-CA 3.36Å; Y316-P383 HydrophobicContact CD1-CB 4.47Å; Y316-P383 HydrophobicContact CE1-CB 4.05Å; P383-V392 HydrophobicContact CG-CG1 3.78Å
384I88.9Confident82.3Confident22 Ų2245.8 Ų45.811%0.11327%0.269CS..PPolyproline II helixtrans-59.1134.6173.8-62.6174000108.9F296 I315 Y442F296-I384 HydrophobicContact CD1-CD1 3.5Å; F296-I384 VanDerWaalsContact CD1-CD1 3.5Å; F296-I384 HydrophobicContact CE1-CD1 3.47Å; F296-I384 VanDerWaalsContact CE1-CD1 3.47Å; I315-I384 HydrophobicContact CG2-CD1 3.93Å; I315-I384 PolarHBondContact O-N 3.03Å; I384-Y442 HydrophobicContact CD1-CE2 4.22Å; I384-Y442 HydrophobicContact CG2-CD2 4.09Å
385P79.8Confident82.1Confident64 Ų6444.8 Ų44.842%0.41627%0.265SS..PPolyproline II helixtrans-59.6141.6177.5-21.632000112.2L441P385-L441 HydrophobicContact CB-CD2 4.35Å
386S67.2Low81.9Confident13 Ų1345.4 Ų45.49%0.09127%0.267CS..BIsolated β-bridgetrans-91.2157.1168.173.50000110.8A388 Y442S386-A388 PolarHBondContact O-N 3.25Å; S386-Y442 CarbonylContact C-O 3.56Å; S386-Y442 WeakPolarHBondContact CA-O 3.47Å; S386-Y442 WeakPolarHBondContact CB-O 3.47Å
387Q56.9Low81.8Confident70 Ų7051.7 Ų51.733%0.32729%0.292SS..SBendtrans-66.8-14.5174-77.4-161.6-23.500113.5G389 D438 L441 Y442 Q443Q387-G389 PolarHBondContact O-N 3.42Å; Q387-D438 PolarHBondContact NE2-OD2 3.04Å; Q387-L441 HydrophobicContact CG-CB 3.47Å; Q387-L441 VanDerWaalsContact CG-CB 3.47Å; Q387-L441 HydrophobicContact CG-CD1 3.85Å; Q387-L441 HydrophobicContact CG-CG 4.32Å; Q387-Y442 PolarHBondContact N-O 3.04Å; Q387-Q443 HydrophobicContact CB-CG 4.49Å; Q387-Q443 VanDerWaalsContact OE1-NE2 3.15Å
388A52.2Low81.5Confident49 Ų4954.9 Ų54.941%0.40531%0.305SS..SBendtrans-79.967.2-171.900000111.7S386S386-A388 PolarHBondContact O-N 3.25Å
389G50.9Low81.4Confident50 Ų5058 Ų5852%0.51532%0.318SS..SBendtrans82.4-175.618000000113.9Q387 H391Q387-G389 PolarHBondContact O-N 3.42Å; G389-H391 PolarHBondContact O-N 2.99Å
390D58.2Low81.1Confident169 Ų16957.7 Ų57.790%0.90432%0.322SS*.SBendtrans-65.719175.3-69-34.9000113.4V392D390-V392 PolarHBondContact O-N 3.47Å
391H63.4Low81.1Confident120 Ų12056 Ų5656%0.55631%0.309SS*.  trans-92.899.9-171.9-64.3-40.3000111.2G389G389-H391 PolarHBondContact O-N 2.99Å
392V76Confident81.1Confident57 Ų5756.7 Ų56.735%0.34531%0.313SS..  trans-76.2123.8163.7-179.80000108.2S272 A382 P383 D390S272-V392 PolarHBondContact OG-O 2.99Å; A382-V392 HydrophobicContact CB-CG1 4.34Å; P383-V392 HydrophobicContact CG-CG1 3.78Å; D390-V392 PolarHBondContact O-N 3.47Å
393G86.6Confident81.3Confident11 Ų1154.4 Ų54.411%0.11329%0.294CS..SBendtrans179.7-171.4-176.600000114.3S270S270-G393 WeakPolarHBondContact O-CA 3.31Å
394P92.4Very high81.5Confident11 Ų1155.3 Ų55.37%0.07130%0.299CS..  trans-66.6142.117728.3-35.2000112S270 L271 A312 I313 C314 F396 Y397S270-P394 VanDerWaalsContact O-CD 3.29Å; S270-P394 WeakPolarHBondContact O-CD 3.25Å; L271-P394 HydrophobicContact CD2-CG 3.61Å; L271-P394 HydrophobicContact CG-CG 4.44Å; A312-P394 HydrophobicContact CB-CB 3.76Å; A312-P394 HydrophobicContact CB-CG 4.16Å; I313-P394 CarbonylContact O-C 3.57Å; I313-P394 VanDerWaalsContact O-CA 3.29Å; I313-P394 WeakPolarHBondContact O-CA 3.49Å; I313-P394 WeakPolarHBondContact O-CB 3.25Å; C314-P394 VanDerWaalsContact SG-CA 3.55Å; P394-F396 VanDerWaalsContact C-N 3.27Å; P394-Y397 HydrophobicContact CG-CD1 4.11Å
395I90.3Very high81.9Confident9 Ų956.6 Ų56.65%0.04630%0.304CS..SBendtrans-70.5-27.8172.252.3150.9000111.5I313 I315 I421 T435 G445I313-I395 HydrophobicContact CB-CD1 4.4Å; I313-I395 HydrophobicContact CB-CG1 4.16Å; I313-I395 HydrophobicContact CG2-CD1 3.94Å; I313-I395 HydrophobicContact CG2-CG1 4.09Å; I313-I395 WeakPolarHBondContact O-CG1 3.49Å; I313-I395 PolarHBondContact O-N 2.83Å; I315-I395 HydrophobicContact CD1-CD1 3.81Å; I315-I395 HydrophobicContact CD1-CG1 4.37Å; I315-I395 HydrophobicContact CD1-CG2 3.97Å; I315-I395 HydrophobicContact CG1-CD1 3.94Å; I315-I395 HydrophobicContact CG1-CG1 4.22Å; I315-I395 HydrophobicContact CG1-CG2 4.26Å; I395-I421 HydrophobicContact CD1-CD1 3.25Å; I395-T435 HydrophobicContact CD1-CG2 3.91Å; I395-G445 WeakPolarHBondContact O-CA 2.97Å; I395-G445 PolarHBondContact O-N 3.13Å
396F92.4Very high82.8Confident16 Ų1653.6 Ų53.67%0.0729%0.285CS..EExtended strand (participates in β ladder)trans-146.4138178.3177.3-95.4000108.8A312 I313 P394 K398 L403 Y431 I433 L447A312-F396 CarbonylContact C-O 3.58Å; A312-F396 VanDerWaalsContact CA-O 3.24Å; A312-F396 WeakPolarHBondContact CA-O 3.44Å; I313-F396 HydrophobicContact CB-CB 4.39Å; I313-F396 HydrophobicContact CD1-CB 4.46Å; I313-F396 HydrophobicContact CD1-CD1 4.14Å; I313-F396 HydrophobicContact CG1-CD1 4.33Å; I313-F396 PolarHBondContact N-O 2.85Å; P394-F396 VanDerWaalsContact C-N 3.27Å; F396-K398 HydrophobicContact CE1-CB 3.98Å; F396-K398 HydrophobicContact CZ-CB 4.04Å; F396-L403 HydrophobicContact CD1-CD1 4.33Å; F396-L403 HydrophobicContact CE1-CD1 4.28Å; F396-Y431 HydrophobicContact CZ-CD1 4.23Å; F396-I433 HydrophobicContact CB-CD1 4.26Å; F396-I433 HydrophobicContact CB-CG2 4.2Å; F396-I433 HydrophobicContact CD1-CD1 3.44Å; F396-I433 VanDerWaalsContact CD1-CD1 3.44Å; F396-I433 HydrophobicContact CD1-CG1 4.38Å; F396-I433 HydrophobicContact CD2-CD1 3.89Å; F396-I433 HydrophobicContact CD2-CG1 3.95Å; F396-I433 HydrophobicContact CD2-CG2 4.06Å; F396-I433 HydrophobicContact CE1-CD1 3.62Å; F396-I433 HydrophobicContact CE1-CG1 4.42Å; F396-I433 HydrophobicContact CE2-CD1 4.06Å; F396-I433 HydrophobicContact CE2-CG1 4.01Å; F396-I433 HydrophobicContact CG-CD1 3.58Å; F396-I433 HydrophobicContact CG-CG1 4.14Å; F396-I433 HydrophobicContact CG-CG2 4.25Å; F396-I433 HydrophobicContact CZ-CD1 3.92Å; F396-I433 HydrophobicContact CZ-CG1 4.24Å; F396-L447 HydrophobicContact CE2-CB 4.19Å
397Y93.1Very high84.2Confident133 Ų13353 Ų5352%0.52228%0.28SS..EExtended strand (participates in β ladder)trans-145.9148.2170.966.6-82.9000110.4L271 S311 P394L271-Y397 HydrophobicContact CD1-CD2 4.27Å; L271-Y397 HydrophobicContact CD1-CE2 4.19Å; L271-Y397 HydrophobicContact CD2-CD1 3.78Å; L271-Y397 HydrophobicContact CD2-CD2 4.47Å; L271-Y397 HydrophobicContact CD2-CE1 3.78Å; L271-Y397 HydrophobicContact CD2-CE2 4.48Å; L271-Y397 HydrophobicContact CD2-CG 4.14Å; S311-Y397 CarbonylContact O-C 3.54Å; S311-Y397 WeakPolarHBondContact O-CA 3.17Å; P394-Y397 HydrophobicContact CG-CD1 4.11Å
398K92.5Very high86Confident70 Ų7050 Ų5030%0.30427%0.267SS..EExtended strand (participates in β ladder)trans-145.9130.3180-165.467.5175.4-1780110.5G310 S311 F396 V401G310-K398 VanDerWaalsContact CA-O 3.31Å; G310-K398 WeakPolarHBondContact CA-O 3.31Å; S311-K398 PolarHBondContact N-O 2.77Å; S311-K398 PolarHBondContact O-N 2.85Å; F396-K398 HydrophobicContact CE1-CB 3.98Å; F396-K398 HydrophobicContact CZ-CB 4.04Å; K398-V401 HydrophobicContact CB-CB 4.14Å; K398-V401 HydrophobicContact CB-CG2 4.34Å; K398-V401 HydrophobicContact CG-CB 3.96Å; K398-V401 HydrophobicContact CG-CG2 3.6Å
399K91.8Very high87.8Confident129 Ų12948.4 Ų48.456%0.56125%0.251SS*.EExtended strand (participates in β ladder)trans-73.7146.8172.9-166.6-166.4166.9-176.30110.1V401K399-V401 PolarHBondContact O-N 2.92Å; K399-V401 VanDerWaalsContact O-N 3.1Å
400D91.7Very high89.6Confident110 Ų11047.8 Ų47.859%0.58824%0.236SC*.THydrogen-bonded Turntrans60.817.3174.9-51.6-46.8000114S309S309-D400 WeakPolarHBondContact O-CA 3.47Å; S309-D400 PolarHBondContact O-N 2.72Å
401V95.3Very high90.8Very high16 Ų1640.3 Ų40.310%0.09720%0.197CC..  trans-122.7129175.4176.30000108.3G310 S311 K398 K399 L403 T425 Y431G310-V401 CarbonylContact C-O 3.5Å; S311-V401 VanDerWaalsContact CB-O 3.28Å; S311-V401 WeakPolarHBondContact CB-O 3.29Å; S311-V401 PolarHBondContact N-O 2.79Å; S311-V401 VanDerWaalsContact N-O 3.11Å; S311-V401 PolarHBondContact OG-O 2.62Å; K398-V401 HydrophobicContact CB-CB 4.14Å; K398-V401 HydrophobicContact CB-CG2 4.34Å; K398-V401 HydrophobicContact CG-CB 3.96Å; K398-V401 HydrophobicContact CG-CG2 3.6Å; K399-V401 PolarHBondContact O-N 2.92Å; K399-V401 VanDerWaalsContact O-N 3.1Å; V401-L403 HydrophobicContact CG1-CD2 3.93Å; V401-L403 HydrophobicContact CG1-CG 4.4Å; V401-T425 HydrophobicContact CG1-CG2 3.89Å; V401-Y431 HydrophobicContact CG1-CE1 4.35Å; V401-Y431 HydrophobicContact CG1-CE2 3.91Å; V401-Y431 WeakPolarHBondContact CG2-OH 3.4Å
402I97.1Very high91.5Very high17 Ų1739.2 Ų39.29%0.08720%0.199CC..  trans-110.4102.8178.9-59.9-58000108.8T302 L305 S311 T404 T425 N426T302-I402 HydrophobicContact CG2-CD1 4.12Å; T302-I402 HydrophobicContact CG2-CG2 3.89Å; L305-I402 HydrophobicContact CD2-CD1 3.65Å; L305-I402 HydrophobicContact CD2-CG1 4.06Å; S311-I402 WeakPolarHBondContact OG-CA 3.27Å; I402-T404 HydrophobicContact CG2-CG2 4.24Å; I402-T425 WeakPolarHBondContact O-CA 3.22Å; I402-T425 WeakPolarHBondContact O-CB 2.94Å; I402-N426 HydrophobicContact CB-CB 4.39Å; I402-N426 HydrophobicContact CG2-CB 4.2Å; I402-N426 PolarHBondContact O-N 3.17Å; I402-N426 VanDerWaalsContact O-N 3.12Å
403L98Very high91.4Very high0 Ų037.2 Ų37.20%019%0.187CC..EExtended strand (participates in β ladder)trans-81.9126.5175.1-60.3-178.9000110T300 S311 I313 F396 V401 A423 G424 T425 Y431T300-L403 HydrophobicContact CG2-CB 4.48Å; T300-L403 WeakPolarHBondContact OG1-CB 3.48Å; S311-L403 PolarHBondContact OG-N 3.2Å; I313-L403 HydrophobicContact CD1-CD1 3.8Å; I313-L403 HydrophobicContact CG1-CD1 3.72Å; F396-L403 HydrophobicContact CD1-CD1 4.33Å; F396-L403 HydrophobicContact CE1-CD1 4.28Å; V401-L403 HydrophobicContact CG1-CD2 3.93Å; V401-L403 HydrophobicContact CG1-CG 4.4Å; L403-A423 HydrophobicContact CD1-CB 4.02Å; L403-A423 HydrophobicContact CD2-CB 3.72Å; L403-A423 HydrophobicContact CG-CB 4.33Å; L403-G424 CarbonylContact C-O 3.49Å; L403-G424 WeakPolarHBondContact CA-O 3.49Å; L403-T425 HydrophobicContact CD2-CG2 3.96Å; L403-Y431 HydrophobicContact CD2-CD2 4.21Å; L403-Y431 HydrophobicContact CD2-CG 4.39Å
404T97.1Very high90.8Very high25 Ų2542.4 Ų42.415%0.15321%0.211CC..EExtended strand (participates in β ladder)trans-115.8-26.4-172.157.50000114.3D284 I402 G424 N426 V459D284-T404 WeakPolarHBondContact CB-O 3.45Å; I402-T404 HydrophobicContact CG2-CG2 4.24Å; T404-G424 PolarHBondContact N-O 3.42Å; T404-G424 PolarHBondContact OG1-O 2.86Å; T404-N426 HydrophobicContact CG2-CB 3.95Å; T404-V459 PolarHBondContact OG1-O 2.9Å
405K98Very high89.8Confident49 Ų4945.4 Ų45.421%0.21324%0.244CC..EExtended strand (participates in β ladder)trans-143.8148.2-176.2-66.3-64.5163.8-147.70112.4D284 A423 G424 V459 Q460 V462D284-K405 HydrophobicContact CB-CD 4.44Å; D284-K405 IonicContact OD1-NZ 2.8Å; D284-K405 PolarHBondContact OD1-NZ 2.82Å; D284-K405 VanDerWaalsContact OD2-CA 3.31Å; D284-K405 WeakPolarHBondContact OD2-CA 3.31Å; K405-A423 CarbonylContact O-C 3.58Å; K405-A423 VanDerWaalsContact O-CA 3.28Å; K405-A423 WeakPolarHBondContact O-CA 3.49Å; K405-G424 PolarHBondContact N-O 2.89Å; K405-G424 PolarHBondContact O-N 2.77Å; K405-V459 HydrophobicContact CB-CG1 4.19Å; K405-V459 HydrophobicContact CG-CG1 4.29Å; K405-Q460 WeakPolarHBondContact CE-O 3.42Å; K405-V462 HydrophobicContact CB-CB 4.38Å; K405-V462 HydrophobicContact CB-CG2 3.71Å
406L97.7Very high89.1Confident2 Ų249.1 Ų49.11%0.0126%0.26CS..EExtended strand (participates in β ladder)trans-128.2143.6-179.3-64-179000111.6D284 Y286 T300 I313 I421 Y422 A423D284-L406 PolarHBondContact OD2-N 3.46Å; Y286-L406 WeakPolarHBondContact CD2-O 3.44Å; T300-L406 HydrophobicContact CG2-CD1 4.02Å; T300-L406 HydrophobicContact CG2-CD2 4.27Å; T300-L406 HydrophobicContact CG2-CG 3.83Å; I313-L406 HydrophobicContact CD1-CD2 4Å; I313-L406 HydrophobicContact CG2-CD1 4.49Å; L406-I421 HydrophobicContact CD2-CG2 3.86Å; L406-Y422 CarbonylContact C-O 3.52Å; L406-Y422 WeakPolarHBondContact CA-O 3.31Å; L406-A423 HydrophobicContact CD2-CB 3.6Å
407A96.4Very high88.5Confident0 Ų050.2 Ų50.20%027%0.266CS..EExtended strand (participates in β ladder)trans-136.2145.515700000109Y286 Y422 V462 L464 L487Y286-A407 HydrophobicContact CD2-CB 4.46Å; Y286-A407 HydrophobicContact CE2-CB 4.13Å; A407-Y422 PolarHBondContact N-O 2.78Å; A407-Y422 PolarHBondContact O-N 2.74Å; A407-V462 HydrophobicContact CB-CB 4.31Å; A407-V462 HydrophobicContact CB-CG1 3.58Å; A407-L464 HydrophobicContact CB-CB 4.25Å; A407-L487 HydrophobicContact CB-CD1 4.03Å
408V94.1Very high87.9Confident8 Ų844.4 Ų44.45%0.04824%0.243CC..EExtended strand (participates in β ladder)trans-129.2134.1-175.2-174.90000110.3Y286 V288 Y298 V420 I421Y286-V408 HydrophobicContact CD1-CB 3.77Å; Y286-V408 HydrophobicContact CD1-CG2 3.86Å; Y286-V408 HydrophobicContact CE1-CB 4.08Å; Y286-V408 HydrophobicContact CG-CG2 4.32Å; V288-V408 HydrophobicContact CG2-CB 3.76Å; V288-V408 HydrophobicContact CG2-CG1 3.96Å; V288-V408 HydrophobicContact CG2-CG2 4.39Å; Y298-V408 HydrophobicContact CD1-CG1 4.44Å; Y298-V408 HydrophobicContact CD1-CG2 3.97Å; Y298-V408 HydrophobicContact CD2-CG1 4.38Å; Y298-V408 HydrophobicContact CD2-CG2 4.06Å; Y298-V408 HydrophobicContact CE1-CG1 4.17Å; Y298-V408 HydrophobicContact CE2-CG1 4.13Å; Y298-V408 HydrophobicContact CG-CG2 3.72Å; V408-V420 WeakPolarHBondContact CA-O 3.41Å; V408-I421 HydrophobicContact CG1-CG1 4.29Å; V408-I421 HydrophobicContact CG2-CG1 4.02Å; V408-I421 HydrophobicContact CG2-CG2 4.34Å
409D91.5Very high87.7Confident14 Ų1441 Ų418%0.07523%0.229CC..EExtended strand (participates in β ladder)trans-112.7150.6170.3-167.826.9000111P411 P419 V420 Y422 L464 K485 Y517D409-P411 WeakPolarHBondContact O-CD 3.33Å; D409-P419 CarbonylContact O-C 3.56Å; D409-P419 WeakPolarHBondContact O-CA 3.34Å; D409-V420 PolarHBondContact N-O 2.85Å; D409-V420 PolarHBondContact O-N 3.07Å; D409-Y422 HydrophobicContact CB-CE2 4.5Å; D409-L464 HydrophobicContact CB-CD1 3.79Å; D409-L464 HydrophobicContact CB-CD2 4.44Å; D409-K485 IonicContact OD1-NZ 3.08Å; D409-K485 PolarHBondContact OD1-NZ 3.31Å; D409-K485 VanDerWaalsContact OD2-CD 3.31Å; D409-K485 WeakPolarHBondContact OD2-CD 3.11Å; D409-K485 IonicContact OD2-NZ 2.67Å; D409-K485 PolarHBondContact OD2-NZ 2.08Å; D409-Y517 VanDerWaalsContact CB-OH 3.26Å; D409-Y517 WeakPolarHBondContact CB-OH 3.1Å; D409-Y517 VanDerWaalsContact CG-OH 3.3Å; D409-Y517 VanDerWaalsContact OD2-CE1 3.29Å; D409-Y517 WeakPolarHBondContact OD2-CE1 3.36Å; D409-Y517 PolarHBondContact OD2-OH 2.83Å
410L87.5Confident87.6Confident37 Ų3734.9 Ų34.919%0.19420%0.202CC..  trans-119.268.3177.5-64-174.8000111.2V288 N290 P419V288-L410 HydrophobicContact CG1-CD1 3.26Å; V288-L410 HydrophobicContact CG1-CD2 4.17Å; V288-L410 HydrophobicContact CG1-CG 3.67Å; N290-L410 HydrophobicContact CB-CD1 4.46Å; L410-P419 HydrophobicContact CD2-CB 3.59Å; L410-P419 HydrophobicContact CD2-CG 3.68Å
411P83.6Confident87.8Confident13 Ų1329.7 Ų29.78%0.08417%0.174CC..  trans-64138.6172.527.7-33.7000110.8D409 F418 V420 P516 Y517D409-P411 WeakPolarHBondContact O-CD 3.33Å; P411-F418 WeakPolarHBondContact CD-O 3.49Å; P411-F418 HydrophobicContact CG-CB 4.23Å; P411-F418 WeakPolarHBondContact CG-O 3.23Å; P411-F418 PolarHBondContact O-N 2.85Å; P411-V420 HydrophobicContact CG-CG2 4.05Å; P411-P516 HydrophobicContact CB-CB 4.18Å; P411-P516 HydrophobicContact CB-CG 4.37Å; P411-P516 HydrophobicContact CG-CB 3.81Å; P411-P516 HydrophobicContact CG-CG 3.57Å; P411-Y517 HydrophobicContact CB-CE1 3.96Å; P411-Y517 HydrophobicContact CG-CE1 4.06Å
412V78.6Confident87.8Confident97 Ų9729.3 Ų29.359%0.58817%0.171SC*.EExtended strand (participates in β ladder)trans-105.4125174.1-177.90000108.5K416 M417V412-K416 CarbonylContact C-O 3.46Å; V412-K416 VanDerWaalsContact CA-O 3.29Å; V412-K416 WeakPolarHBondContact CA-O 3.47Å; V412-M417 HydrophobicContact CG2-CG 4.21Å
413V74.6Confident87.9Confident15 Ų1528.5 Ų28.59%0.09117%0.167CC..EExtended strand (participates in β ladder)trans-127.1123.8177.6176.70000107.5G415 K416 F418 P516 S542V413-G415 PolarHBondContact O-N 2.98Å; V413-G415 VanDerWaalsContact O-N 3.14Å; V413-K416 PolarHBondContact N-O 2.75Å; V413-K416 PolarHBondContact O-N 3.37Å; V413-F418 HydrophobicContact CB-CD2 3.77Å; V413-F418 HydrophobicContact CB-CE2 3.67Å; V413-F418 HydrophobicContact CG1-CE2 4.35Å; V413-F418 HydrophobicContact CG2-CD2 4.01Å; V413-F418 HydrophobicContact CG2-CE2 4.36Å; V413-P516 HydrophobicContact CG2-CB 3.96Å; V413-S542 WeakPolarHBondContact CG1-OG 3.44Å
414D72.9Confident87.9Confident119 Ų11928.5 Ų28.564%0.63617%0.167SC*.THydrogen-bonded Turntrans49.540.3-179.7-61.1-21000113.8K416 T544D414-K416 PolarHBondContact O-N 3.26Å; D414-T544 HydrophobicContact CB-CG2 3.93Å
415G72.5Confident87.9Confident74 Ų7427.3 Ų27.376%0.76316%0.16SC*.THydrogen-bonded Turntrans75.9-2.6-179.200000115.2V413V413-G415 PolarHBondContact O-N 2.98Å; V413-G415 VanDerWaalsContact O-N 3.14Å
416K75.1Confident87.8Confident87 Ų8728.3 Ų28.338%0.37817%0.168SC..EExtended strand (participates in β ladder)trans-100.7146.8174.6-62.7-171.8-179.3-169.20111V412 V413 D414 F418V412-K416 CarbonylContact C-O 3.46Å; V412-K416 VanDerWaalsContact CA-O 3.29Å; V412-K416 WeakPolarHBondContact CA-O 3.47Å; V413-K416 PolarHBondContact N-O 2.75Å; V413-K416 PolarHBondContact O-N 3.37Å; D414-K416 PolarHBondContact O-N 3.26Å; K416-F418 HydrophobicContact CB-CE2 3.82Å; K416-F418 HydrophobicContact CB-CZ 4.49Å
417M78.7Confident87.7Confident39 Ų3931.3 Ų31.319%0.19218%0.184CC..EExtended strand (participates in β ladder)trans-92.3137.4177-63.8174.5-74.300111N290 V412 P419 M437N290-M417 WeakPolarHBondContact ND2-CE 3.41Å; N290-M417 PolarHBondContact ND2-SD 3.02Å; N290-M417 PolarHBondContact OD1-SD 2.83Å; V412-M417 HydrophobicContact CG2-CG 4.21Å; M417-P419 WeakPolarHBondContact O-CD 3.39Å; M417-M437 HydrophobicContact CB-CE 3.8Å; M417-M437 HydrophobicContact CE-CE 3.42Å; M417-M437 VanDerWaalsContact CE-CE 3.42Å; M417-M437 HydrophobicContact CE-SD 3.97Å; M417-M437 HydrophobicContact CG-CE 4.49Å; M417-M437 HydrophobicContact SD-CE 3.81Å
418F81Confident87.6Confident11 Ų1131.3 Ų31.35%0.04818%0.184CC..  trans-123.577.2179.2-73.3-93.9000110.5P411 V413 K416 V420 T435 W436 P516 P546P411-F418 WeakPolarHBondContact CD-O 3.49Å; P411-F418 HydrophobicContact CG-CB 4.23Å; P411-F418 WeakPolarHBondContact CG-O 3.23Å; P411-F418 PolarHBondContact O-N 2.85Å; V413-F418 HydrophobicContact CB-CD2 3.77Å; V413-F418 HydrophobicContact CB-CE2 3.67Å; V413-F418 HydrophobicContact CG1-CE2 4.35Å; V413-F418 HydrophobicContact CG2-CD2 4.01Å; V413-F418 HydrophobicContact CG2-CE2 4.36Å; K416-F418 HydrophobicContact CB-CE2 3.82Å; K416-F418 HydrophobicContact CB-CZ 4.49Å; F418-V420 WeakPolarHBondContact O-CG2 3.34Å; F418-V420 PolarHBondContact O-N 2.91Å; F418-T435 CarbonylContact C-O 3.41Å; F418-T435 WeakPolarHBondContact CA-O 3.23Å; F418-W436 HydrophobicContact CD1-CB 3.73Å; F418-W436 HydrophobicContact CE1-CB 3.72Å; F418-P516 HydrophobicContact CB-CB 3.79Å; F418-P516 HydrophobicContact CB-CG 4.11Å; F418-P516 HydrophobicContact CG-CB 4.24Å; F418-P546 HydrophobicContact CE1-CG 4.19Å
419P87.7Confident87.7Confident0 Ų033 Ų330%019%0.191CC..  trans-59.1124.5-177.2-19.130.1000111.6D409 L410 M417 T435 M437 Y442D409-P419 CarbonylContact O-C 3.56Å; D409-P419 WeakPolarHBondContact O-CA 3.34Å; L410-P419 HydrophobicContact CD2-CB 3.59Å; L410-P419 HydrophobicContact CD2-CG 3.68Å; M417-P419 WeakPolarHBondContact O-CD 3.39Å; P419-T435 WeakPolarHBondContact CB-OG1 3.35Å; P419-T435 VanDerWaalsContact CD-O 3.28Å; P419-T435 WeakPolarHBondContact CD-O 3.43Å; P419-T435 PolarHBondContact O-N 2.71Å; P419-T435 PolarHBondContact O-OG1 3.38Å; P419-M437 HydrophobicContact CG-CE 3.71Å; P419-Y442 HydrophobicContact CG-CE1 3.95Å
420V91.4Very high87.9Confident0 Ų032.4 Ų32.40%019%0.188CC..EExtended strand (participates in β ladder)trans-111.9124.5177-1750000108.8V408 D409 P411 F418 Y422 T432 I433 A434 P516 Y517V408-V420 WeakPolarHBondContact CA-O 3.41Å; D409-V420 PolarHBondContact N-O 2.85Å; D409-V420 PolarHBondContact O-N 3.07Å; P411-V420 HydrophobicContact CG-CG2 4.05Å; F418-V420 WeakPolarHBondContact O-CG2 3.34Å; F418-V420 PolarHBondContact O-N 2.91Å; V420-Y422 HydrophobicContact CB-CE2 4.39Å; V420-Y422 HydrophobicContact CG1-CE1 4.3Å; V420-Y422 HydrophobicContact CG1-CE2 3.89Å; V420-T432 HydrophobicContact CG1-CG2 3.65Å; V420-I433 CarbonylContact C-O 3.56Å; V420-I433 WeakPolarHBondContact CA-O 3.28Å; V420-A434 HydrophobicContact CG2-CB 4.37Å; V420-P516 HydrophobicContact CG2-CG 3.48Å; V420-P516 VanDerWaalsContact CG2-CG 3.48Å; V420-Y517 HydrophobicContact CB-CE2 4.37Å; V420-Y517 HydrophobicContact CG1-CE2 4.38Å; V420-Y517 HydrophobicContact CG2-CE2 3.92Å
421I94.8Very high88.2Confident0 Ų031.5 Ų31.50%018%0.182CC..EExtended strand (participates in β ladder)trans-106.4125.6-178.9-57.9151.6000108.4Y298 I313 I395 L406 V408 I433 T435Y298-I421 HydrophobicContact CD1-CD1 3.81Å; Y298-I421 HydrophobicContact CD1-CG1 3.88Å; Y298-I421 HydrophobicContact CE1-CD1 3.89Å; Y298-I421 HydrophobicContact CE1-CG1 4Å; I313-I421 HydrophobicContact CD1-CG2 3.93Å; I313-I421 HydrophobicContact CG2-CD1 4.36Å; I395-I421 HydrophobicContact CD1-CD1 3.25Å; L406-I421 HydrophobicContact CD2-CG2 3.86Å; V408-I421 HydrophobicContact CG1-CG1 4.29Å; V408-I421 HydrophobicContact CG2-CG1 4.02Å; V408-I421 HydrophobicContact CG2-CG2 4.34Å; I421-I433 HydrophobicContact CB-CB 4.4Å; I421-I433 PolarHBondContact N-O 2.87Å; I421-I433 PolarHBondContact O-N 2.68Å; I421-T435 HydrophobicContact CD1-CG2 4.34Å
422Y96.7Very high88.7Confident8 Ų831.6 Ų31.63%0.03118%0.182CC..EExtended strand (participates in β ladder)trans-100.9114.4169.9-60.2-81000108.2L406 A407 D409 V420 I430 Y431 T432 L464 L487 I500 Y517L406-Y422 CarbonylContact C-O 3.52Å; L406-Y422 WeakPolarHBondContact CA-O 3.31Å; A407-Y422 PolarHBondContact N-O 2.78Å; A407-Y422 PolarHBondContact O-N 2.74Å; D409-Y422 HydrophobicContact CB-CE2 4.5Å; V420-Y422 HydrophobicContact CB-CE2 4.39Å; V420-Y422 HydrophobicContact CG1-CE1 4.3Å; V420-Y422 HydrophobicContact CG1-CE2 3.89Å; Y422-I430 HydrophobicContact CD1-CG2 4.36Å; Y422-Y431 CarbonylContact C-O 3.44Å; Y422-Y431 WeakPolarHBondContact CA-O 3.46Å; Y422-T432 HydrophobicContact CD1-CG2 4.17Å; Y422-T432 HydrophobicContact CE1-CG2 3.64Å; Y422-L464 HydrophobicContact CD2-CD1 3.91Å; Y422-L464 HydrophobicContact CE2-CD1 3.78Å; Y422-L487 HydrophobicContact CD1-CD2 3.99Å; Y422-L487 HydrophobicContact CD2-CD1 4.05Å; Y422-L487 HydrophobicContact CG-CD1 3.92Å; Y422-L487 HydrophobicContact CG-CD2 3.99Å; Y422-I500 HydrophobicContact CE1-CG1 4.34Å; Y422-I500 HydrophobicContact CE2-CD1 3.94Å; Y422-I500 HydrophobicContact CE2-CG1 4.32Å; Y422-I500 WeakPolarHBondContact OH-CG2 3.41Å; Y422-Y517 WeakPolarHBondContact OH-CE2 3.19Å
423A98Very high89.3Confident0 Ų027 Ų270%015%0.154CC..EExtended strand (participates in β ladder)trans-114.7117.7-178.600000110.7I313 L403 K405 L406 I430 Y431I313-A423 HydrophobicContact CD1-CB 4.18Å; L403-A423 HydrophobicContact CD1-CB 4.02Å; L403-A423 HydrophobicContact CD2-CB 3.72Å; L403-A423 HydrophobicContact CG-CB 4.33Å; K405-A423 CarbonylContact O-C 3.58Å; K405-A423 VanDerWaalsContact O-CA 3.28Å; K405-A423 WeakPolarHBondContact O-CA 3.49Å; L406-A423 HydrophobicContact CD2-CB 3.6Å; A423-I430 WeakPolarHBondContact O-CA 3.46Å; A423-Y431 PolarHBondContact N-O 2.84Å; A423-Y431 PolarHBondContact O-N 2.6Å
424G97.8Very high89.8Confident0 Ų026.7 Ų26.70%015%0.153CC..EExtended strand (participates in β ladder)trans-84.215117400000112.1L403 T404 K405 E429L403-G424 CarbonylContact C-O 3.49Å; L403-G424 WeakPolarHBondContact CA-O 3.49Å; T404-G424 PolarHBondContact N-O 3.42Å; T404-G424 PolarHBondContact OG1-O 2.86Å; K405-G424 PolarHBondContact N-O 2.89Å; K405-G424 PolarHBondContact O-N 2.77Å; G424-E429 CarbonylContact C-O 3.52Å; G424-E429 WeakPolarHBondContact CA-O 3.43Å
425T97.9Very high90.1Very high0 Ų021 Ų210%012%0.123CC..EExtended strand (participates in β ladder)trans-113170.2-179.662.70000113.9V401 I402 L403 N427 G428 E429 Y431 V459V401-T425 HydrophobicContact CG1-CG2 3.89Å; I402-T425 WeakPolarHBondContact O-CA 3.22Å; I402-T425 WeakPolarHBondContact O-CB 2.94Å; L403-T425 HydrophobicContact CD2-CG2 3.96Å; T425-N427 VanDerWaalsContact CB-OD1 3.25Å; T425-N427 WeakPolarHBondContact CB-OD1 3.21Å; T425-N427 PolarHBondContact O-N 3.13Å; T425-N427 PolarHBondContact OG1-N 2.72Å; T425-N427 PolarHBondContact OG1-OD1 2.86Å; T425-G428 PolarHBondContact OG1-N 3.01Å; T425-E429 HydrophobicContact CG2-CB 3.96Å; T425-E429 PolarHBondContact N-O 2.7Å; T425-E429 WeakPolarHBondContact OG1-CA 3.29Å; T425-E429 WeakPolarHBondContact OG1-CB 3.38Å; T425-E429 PolarHBondContact OG1-N 2.68Å; T425-E429 PolarHBondContact OG1-O 2.85Å; T425-Y431 HydrophobicContact CG2-CD2 3.77Å; T425-Y431 HydrophobicContact CG2-CE2 3.56Å; T425-V459 PolarHBondContact O-N 3Å
426N95.8Very high90.1Very high71 Ų7118.6 Ų18.638%0.389%0.091SC..THydrogen-bonded Turntrans-71-1.6169.772.2-22.1000114.9I402 T404 P458I402-N426 HydrophobicContact CB-CB 4.39Å; I402-N426 HydrophobicContact CG2-CB 4.2Å; I402-N426 PolarHBondContact O-N 3.17Å; I402-N426 VanDerWaalsContact O-N 3.12Å; T404-N426 HydrophobicContact CG2-CB 3.95Å; N426-P458 WeakPolarHBondContact O-CA 3.45Å; N426-P458 VanDerWaalsContact O-CG 3.31Å; N426-P458 WeakPolarHBondContact O-CG 3.46Å
427N95.2Very high89.6Confident65 Ų6515.9 Ų15.935%0.3488%0.08SC..THydrogen-bonded Turntrans-126.414.6-177.170-10000113.9T425 E429 R456T425-N427 VanDerWaalsContact CB-OD1 3.25Å; T425-N427 WeakPolarHBondContact CB-OD1 3.21Å; T425-N427 PolarHBondContact O-N 3.13Å; T425-N427 PolarHBondContact OG1-N 2.72Å; T425-N427 PolarHBondContact OG1-OD1 2.86Å; N427-E429 WeakPolarHBondContact OD1-CG 3.4Å; N427-R456 CarbonylContact O-C 3.4Å; N427-R456 WeakPolarHBondContact O-CA 3.29Å
428G95.3Very high88.7Confident0 Ų017.1 Ų17.10%09%0.087CC..SBendtrans83.129.7173.400000114.5T425 L453 E457T425-G428 PolarHBondContact OG1-N 3.01Å; G428-L453 VanDerWaalsContact O-CB 3.28Å; G428-L453 WeakPolarHBondContact O-CB 3.43Å; G428-L453 WeakPolarHBondContact O-CG 3.48Å; G428-L453 PolarHBondContact O-N 2.78Å; G428-E457 WeakPolarHBondContact CA-O 3.48Å; G428-E457 PolarHBondContact N-O 2.75Å
429E95.3Very high87.5Confident43 Ų4322.3 Ų22.320%0.20113%0.125CC..EExtended strand (participates in β ladder)trans-107.4144.3174.4-62.2178.1157.900110.5G424 T425 N427 Y431 V450 Q451 L452G424-E429 CarbonylContact C-O 3.52Å; G424-E429 WeakPolarHBondContact CA-O 3.43Å; T425-E429 HydrophobicContact CG2-CB 3.96Å; T425-E429 PolarHBondContact N-O 2.7Å; T425-E429 WeakPolarHBondContact OG1-CA 3.29Å; T425-E429 WeakPolarHBondContact OG1-CB 3.38Å; T425-E429 PolarHBondContact OG1-N 2.68Å; T425-E429 PolarHBondContact OG1-O 2.85Å; N427-E429 WeakPolarHBondContact OD1-CG 3.4Å; E429-Y431 HydrophobicContact CB-CD2 4.26Å; E429-Y431 HydrophobicContact CB-CE2 3.77Å; E429-Y431 VanDerWaalsContact OE2-CE2 3.29Å; E429-Y431 WeakPolarHBondContact OE2-CE2 3.23Å; E429-Y431 PolarHBondContact OE2-OH 2.94Å; E429-V450 HydrophobicContact CB-CG1 4.01Å; E429-V450 HydrophobicContact CG-CG1 4.27Å; E429-Q451 CarbonylContact C-O 3.59Å; E429-Q451 WeakPolarHBondContact CA-O 3.39Å; E429-L452 HydrophobicContact CG-CD1 3.88Å
430I95.4Very high86Confident2 Ų226.2 Ų26.21%0.0116%0.157CC..EExtended strand (participates in β ladder)trans-114113.3170.6-57.8-58.9000108.8Y422 A423 V450 Q451 L453 V459 L487 V489 L498Y422-I430 HydrophobicContact CD1-CG2 4.36Å; A423-I430 WeakPolarHBondContact O-CA 3.46Å; I430-V450 WeakPolarHBondContact O-CA 3.39Å; I430-Q451 HydrophobicContact CB-CB 4.43Å; I430-Q451 PolarHBondContact N-O 2.67Å; I430-Q451 PolarHBondContact O-N 3.2Å; I430-L453 HydrophobicContact CD1-CD1 4.3Å; I430-L453 HydrophobicContact CG1-CD1 4.3Å; I430-L453 HydrophobicContact CG1-CD2 4.09Å; I430-L453 HydrophobicContact CG1-CG 4.23Å; I430-V459 HydrophobicContact CD1-CG2 3.97Å; I430-L487 HydrophobicContact CG2-CD2 3.96Å; I430-V489 HydrophobicContact CD1-CG1 3.96Å; I430-V489 HydrophobicContact CD1-CG2 4.01Å; I430-V489 HydrophobicContact CG1-CG2 4.35Å; I430-L498 HydrophobicContact CG1-CD1 4.39Å
431Y95Very high84.6Confident17 Ų1729.1 Ų29.17%0.06717%0.172CC..EExtended strand (participates in β ladder)trans-87.7125.5173.3-73.8-113.8000108.6F396 V401 L403 Y422 A423 T425 E429 L447 V450F396-Y431 HydrophobicContact CZ-CD1 4.23Å; V401-Y431 HydrophobicContact CG1-CE1 4.35Å; V401-Y431 HydrophobicContact CG1-CE2 3.91Å; V401-Y431 WeakPolarHBondContact CG2-OH 3.4Å; L403-Y431 HydrophobicContact CD2-CD2 4.21Å; L403-Y431 HydrophobicContact CD2-CG 4.39Å; Y422-Y431 CarbonylContact C-O 3.44Å; Y422-Y431 WeakPolarHBondContact CA-O 3.46Å; A423-Y431 PolarHBondContact N-O 2.84Å; A423-Y431 PolarHBondContact O-N 2.6Å; T425-Y431 HydrophobicContact CG2-CD2 3.77Å; T425-Y431 HydrophobicContact CG2-CE2 3.56Å; E429-Y431 HydrophobicContact CB-CD2 4.26Å; E429-Y431 HydrophobicContact CB-CE2 3.77Å; E429-Y431 VanDerWaalsContact OE2-CE2 3.29Å; E429-Y431 WeakPolarHBondContact OE2-CE2 3.23Å; E429-Y431 PolarHBondContact OE2-OH 2.94Å; Y431-L447 HydrophobicContact CD1-CD1 3.66Å; Y431-L447 HydrophobicContact CD1-CD2 4.37Å; Y431-L447 HydrophobicContact CE1-CD1 4.49Å; Y431-L447 HydrophobicContact CE1-CD2 4.45Å; Y431-L447 HydrophobicContact CG-CD1 4.37Å; Y431-V450 HydrophobicContact CD1-CG2 3.76Å; Y431-V450 HydrophobicContact CD2-CG1 4.26Å; Y431-V450 HydrophobicContact CE1-CG2 3.6Å; Y431-V450 HydrophobicContact CE2-CG1 3.86Å; Y431-V450 HydrophobicContact CE2-CG2 4.35Å; Y431-V450 HydrophobicContact CG-CG2 4.19Å
432T92.8Very high83.1Confident15 Ų1529.4 Ų29.49%0.09217%0.174CC..EExtended strand (participates in β ladder)trans-103115.6172.1-56.10000108.5V420 Y422 L448 S449V420-T432 HydrophobicContact CG1-CG2 3.65Å; Y422-T432 HydrophobicContact CD1-CG2 4.17Å; Y422-T432 HydrophobicContact CE1-CG2 3.64Å; T432-L448 HydrophobicContact CG2-CB 4.2Å; T432-L448 HydrophobicContact CG2-CD1 4.17Å; T432-L448 WeakPolarHBondContact O-CB 3.45Å; T432-L448 PolarHBondContact O-N 3.45Å; T432-S449 WeakPolarHBondContact CB-OG 3.32Å; T432-S449 PolarHBondContact N-O 3.02Å; T432-S449 PolarHBondContact O-N 3.36Å; T432-S449 PolarHBondContact OG1-OG 2.72Å
433I90.7Very high81.7Confident0 Ų031.5 Ų31.50%018%0.183CC..EExtended strand (participates in β ladder)trans-120.9122.9-175.1-61.1150.5000108I313 F396 V420 I421 N446 L447I313-I433 HydrophobicContact CD1-CD1 3.67Å; F396-I433 HydrophobicContact CB-CD1 4.26Å; F396-I433 HydrophobicContact CB-CG2 4.2Å; F396-I433 HydrophobicContact CD1-CD1 3.44Å; F396-I433 VanDerWaalsContact CD1-CD1 3.44Å; F396-I433 HydrophobicContact CD1-CG1 4.38Å; F396-I433 HydrophobicContact CD2-CD1 3.89Å; F396-I433 HydrophobicContact CD2-CG1 3.95Å; F396-I433 HydrophobicContact CD2-CG2 4.06Å; F396-I433 HydrophobicContact CE1-CD1 3.62Å; F396-I433 HydrophobicContact CE1-CG1 4.42Å; F396-I433 HydrophobicContact CE2-CD1 4.06Å; F396-I433 HydrophobicContact CE2-CG1 4.01Å; F396-I433 HydrophobicContact CG-CD1 3.58Å; F396-I433 HydrophobicContact CG-CG1 4.14Å; F396-I433 HydrophobicContact CG-CG2 4.25Å; F396-I433 HydrophobicContact CZ-CD1 3.92Å; F396-I433 HydrophobicContact CZ-CG1 4.24Å; V420-I433 CarbonylContact C-O 3.56Å; V420-I433 WeakPolarHBondContact CA-O 3.28Å; I421-I433 HydrophobicContact CB-CB 4.4Å; I421-I433 PolarHBondContact N-O 2.87Å; I421-I433 PolarHBondContact O-N 2.68Å; I433-N446 CarbonylContact C-O 3.58Å; I433-N446 WeakPolarHBondContact CA-O 3.26Å; I433-L447 HydrophobicContact CG1-CD1 4.19Å
434A85.5Confident80.6Confident9 Ų935.3 Ų35.37%0.07420%0.204CC..EExtended strand (participates in β ladder)trans-103.2139.6175.600000111.1V420 G445 N446 L448V420-A434 HydrophobicContact CG2-CB 4.37Å; A434-G445 WeakPolarHBondContact O-CA 3.45Å; A434-N446 PolarHBondContact N-O 3Å; A434-N446 PolarHBondContact O-N 3.25Å; A434-L448 HydrophobicContact CB-CD1 3.61Å; A434-L448 HydrophobicContact CB-CD2 4.07Å; A434-L448 HydrophobicContact CB-CG 3.82Å
435T80.6Confident79.6Confident0 Ų035.9 Ų35.90%021%0.21CC..  trans-122159.1170.464.40000108.3I395 F418 P419 I421I395-T435 HydrophobicContact CD1-CG2 3.91Å; F418-T435 CarbonylContact C-O 3.41Å; F418-T435 WeakPolarHBondContact CA-O 3.23Å; P419-T435 WeakPolarHBondContact CB-OG1 3.35Å; P419-T435 VanDerWaalsContact CD-O 3.28Å; P419-T435 WeakPolarHBondContact CD-O 3.43Å; P419-T435 PolarHBondContact O-N 2.71Å; P419-T435 PolarHBondContact O-OG1 3.38Å; I421-T435 HydrophobicContact CD1-CG2 4.34Å
436W71.9Confident78.7Confident24 Ų2438.6 Ų38.69%0.09123%0.225CC..  trans-133.6148.3169.363.1101.4000109F418 Q443 N446 T547F418-W436 HydrophobicContact CD1-CB 3.73Å; F418-W436 HydrophobicContact CE1-CB 3.72Å; W436-Q443 HydrophobicContact CD2-CB 4.12Å; W436-Q443 HydrophobicContact CD2-CG 4.35Å; W436-Q443 HydrophobicContact CE3-CB 4.39Å; W436-Q443 HydrophobicContact CH2-CB 4.25Å; W436-Q443 HydrophobicContact CZ2-CB 4.08Å; W436-Q443 HydrophobicContact CZ2-CG 4.26Å; W436-Q443 HydrophobicContact CZ3-CB 4.39Å; W436-Q443 VanDerWaalsContact NE1-OE1 3.14Å; W436-Q443 PolarHBondContact O-N 3.32Å; W436-N446 VanDerWaalsContact CH2-ND2 3.33Å; W436-N446 WeakPolarHBondContact CH2-ND2 3.01Å; W436-N446 WeakPolarHBondContact CZ3-ND2 3.5Å; W436-T547 HydrophobicContact CH2-CG2 4.21Å; W436-T547 HydrophobicContact CZ2-CG2 4.15Å
437M65.4Low78.2Confident30 Ų3038.5 Ų38.515%0.14822%0.224CC..EExtended strand (participates in β ladder)trans-100.5135.4176.9-76.9-175.1-95.700110M417 P419 L441 Y442M417-M437 HydrophobicContact CB-CE 3.8Å; M417-M437 HydrophobicContact CE-CE 3.42Å; M417-M437 VanDerWaalsContact CE-CE 3.42Å; M417-M437 HydrophobicContact CE-SD 3.97Å; M417-M437 HydrophobicContact CG-CE 4.49Å; M417-M437 HydrophobicContact SD-CE 3.81Å; P419-M437 HydrophobicContact CG-CE 3.71Å; M437-L441 WeakPolarHBondContact CA-O 3.29Å; M437-Y442 HydrophobicContact CE-CE1 4.35Å; M437-Y442 HydrophobicContact CG-CD1 4.05Å; M437-Y442 HydrophobicContact CG-CE1 4Å; M437-Y442 HydrophobicContact CG-CE2 4.43Å; M437-Y442 HydrophobicContact CG-CG 4.31Å; M437-Y442 HydrophobicContact SD-CE1 4.25Å; M437-Y442 HydrophobicContact SD-CE2 4.15Å
438D58.6Low77.5Confident65 Ų6537.4 Ų37.435%0.34822%0.218SC..EExtended strand (participates in β ladder)trans-121.1129166-178.336.5000110.4Q387 A440 L441Q387-D438 PolarHBondContact NE2-OD2 3.04Å; D438-A440 PolarHBondContact O-N 2.82Å; D438-L441 PolarHBondContact N-O 2.71Å; D438-L441 VanDerWaalsContact N-O 3.09Å; D438-L441 PolarHBondContact O-N 2.96Å
439S55.3Low77Confident120 Ų12039.7 Ų39.784%0.83923%0.233SC*.THydrogen-bonded Turntrans33.9-13.2-173.863.10000121.4
440A56.5Low76.7Confident81 Ų8140.8 Ų40.867%0.66924%0.243SC*.THydrogen-bonded Turntrans178-7.2170.600000113.5D438D438-A440 PolarHBondContact O-N 2.82Å
441L62.1Low76.3Confident62 Ų6242.9 Ų42.933%0.32525%0.253SS..EExtended strand (participates in β ladder)trans-124.5147.4-165.9-66.9171.7000112.6P385 Q387 M437 D438P385-L441 HydrophobicContact CB-CD2 4.35Å; Q387-L441 HydrophobicContact CG-CB 3.47Å; Q387-L441 VanDerWaalsContact CG-CB 3.47Å; Q387-L441 HydrophobicContact CG-CD1 3.85Å; Q387-L441 HydrophobicContact CG-CG 4.32Å; M437-L441 WeakPolarHBondContact CA-O 3.29Å; D438-L441 PolarHBondContact N-O 2.71Å; D438-L441 VanDerWaalsContact N-O 3.09Å; D438-L441 PolarHBondContact O-N 2.96Å
442Y63.6Low76.1Confident6 Ų646.1 Ų46.12%0.02427%0.27CS..EExtended strand (participates in β ladder)trans-81.3146.2175.6-75.5-92.4000111.4Y298 I315 I384 S386 Q387 P419 M437Y298-Y442 PolarHBondContact OH-OH 2.97Å; I315-Y442 HydrophobicContact CD1-CD1 3.6Å; I315-Y442 HydrophobicContact CD1-CD2 4.18Å; I315-Y442 HydrophobicContact CD1-CE1 3.44Å; I315-Y442 VanDerWaalsContact CD1-CE1 3.44Å; I315-Y442 HydrophobicContact CD1-CE2 4.07Å; I315-Y442 HydrophobicContact CD1-CG 3.96Å; I315-Y442 HydrophobicContact CG2-CE2 4.42Å; I384-Y442 HydrophobicContact CD1-CE2 4.22Å; I384-Y442 HydrophobicContact CG2-CD2 4.09Å; S386-Y442 CarbonylContact C-O 3.56Å; S386-Y442 WeakPolarHBondContact CA-O 3.47Å; S386-Y442 WeakPolarHBondContact CB-O 3.47Å; Q387-Y442 PolarHBondContact N-O 3.04Å; P419-Y442 HydrophobicContact CG-CE1 3.95Å; M437-Y442 HydrophobicContact CE-CE1 4.35Å; M437-Y442 HydrophobicContact CG-CD1 4.05Å; M437-Y442 HydrophobicContact CG-CE1 4Å; M437-Y442 HydrophobicContact CG-CE2 4.43Å; M437-Y442 HydrophobicContact CG-CG 4.31Å; M437-Y442 HydrophobicContact SD-CE1 4.25Å; M437-Y442 HydrophobicContact SD-CE2 4.15Å
443Q67.4Low76Confident51 Ų5145.6 Ų45.624%0.23827%0.267CS..PPolyproline II helixtrans-94.2169.7164.5-60.5-151.25.800111.6Q387 W436Q387-Q443 HydrophobicContact CB-CG 4.49Å; Q387-Q443 VanDerWaalsContact OE1-NE2 3.15Å; W436-Q443 HydrophobicContact CD2-CB 4.12Å; W436-Q443 HydrophobicContact CD2-CG 4.35Å; W436-Q443 HydrophobicContact CE3-CB 4.39Å; W436-Q443 HydrophobicContact CH2-CB 4.25Å; W436-Q443 HydrophobicContact CZ2-CB 4.08Å; W436-Q443 HydrophobicContact CZ2-CG 4.26Å; W436-Q443 HydrophobicContact CZ3-CB 4.39Å; W436-Q443 VanDerWaalsContact NE1-OE1 3.14Å; W436-Q443 PolarHBondContact O-N 3.32Å
444N73.8Confident75.4Confident80 Ų8049.8 Ų49.843%0.42830%0.295SS..PPolyproline II helixtrans-57.5139.8173.3-71.4-11.1000110.2N446N444-N446 PolarHBondContact O-N 3.16Å
445G78.2Confident75.4Confident12 Ų1250.4 Ų50.412%0.12430%0.298CS..PPolyproline II helixtrans-69.5122.1177.100000111.3I395 A434I395-G445 WeakPolarHBondContact O-CA 2.97Å; I395-G445 PolarHBondContact O-N 3.13Å; A434-G445 WeakPolarHBondContact O-CA 3.45Å
446N79.4Confident75.9Confident58 Ų5860 Ų6031%0.3133%0.334SS..EExtended strand (participates in β ladder)trans-90.2124.1174.4-73.8-21.5000109.8I433 A434 W436 N444 L448I433-N446 CarbonylContact C-O 3.58Å; I433-N446 WeakPolarHBondContact CA-O 3.26Å; A434-N446 PolarHBondContact N-O 3Å; A434-N446 PolarHBondContact O-N 3.25Å; W436-N446 VanDerWaalsContact CH2-ND2 3.33Å; W436-N446 WeakPolarHBondContact CH2-ND2 3.01Å; W436-N446 WeakPolarHBondContact CZ3-ND2 3.5Å; N444-N446 PolarHBondContact O-N 3.16Å; N446-L448 PolarHBondContact O-N 3.46Å
447L83.9Confident76.9Confident69 Ų6961 Ų6136%0.36134%0.34SS..EExtended strand (participates in β ladder)trans-68.5115.7171.3-178.960.7000109.7F396 Y431 I433 V450F396-L447 HydrophobicContact CE2-CB 4.19Å; Y431-L447 HydrophobicContact CD1-CD1 3.66Å; Y431-L447 HydrophobicContact CD1-CD2 4.37Å; Y431-L447 HydrophobicContact CE1-CD1 4.49Å; Y431-L447 HydrophobicContact CE1-CD2 4.45Å; Y431-L447 HydrophobicContact CG-CD1 4.37Å; I433-L447 HydrophobicContact CG1-CD1 4.19Å; L447-V450 HydrophobicContact CD1-CG2 4.12Å; L447-V450 HydrophobicContact CD2-CG2 4.11Å
448L82Confident78.4Confident42 Ų4262.2 Ų62.222%0.2235%0.35CS..EExtended strand (participates in β ladder)trans-87.6-44.9178.1-62.2-168.2000112.2T432 A434 N446 Q514T432-L448 HydrophobicContact CG2-CB 4.2Å; T432-L448 HydrophobicContact CG2-CD1 4.17Å; T432-L448 WeakPolarHBondContact O-CB 3.45Å; T432-L448 PolarHBondContact O-N 3.45Å; A434-L448 HydrophobicContact CB-CD1 3.61Å; A434-L448 HydrophobicContact CB-CD2 4.07Å; A434-L448 HydrophobicContact CB-CG 3.82Å; N446-L448 PolarHBondContact O-N 3.46Å; L448-Q514 HydrophobicContact CD2-CB 3.67Å
449S84.4Confident80.2Confident47 Ų4759.3 Ų59.333%0.32934%0.335SS..EExtended strand (participates in β ladder)trans-160.9158.8-177.266.20000111.9T432T432-S449 WeakPolarHBondContact CB-OG 3.32Å; T432-S449 PolarHBondContact N-O 3.02Å; T432-S449 PolarHBondContact O-N 3.36Å; T432-S449 PolarHBondContact OG1-OG 2.72Å
450V88.1Confident82.2Confident67 Ų6755.8 Ų55.841%0.40631%0.305SS..EExtended strand (participates in β ladder)trans-122.9118.1167.1-176.80000107.2E429 I430 Y431 L447E429-V450 HydrophobicContact CB-CG1 4.01Å; E429-V450 HydrophobicContact CG-CG1 4.27Å; I430-V450 WeakPolarHBondContact O-CA 3.39Å; Y431-V450 HydrophobicContact CD1-CG2 3.76Å; Y431-V450 HydrophobicContact CD2-CG1 4.26Å; Y431-V450 HydrophobicContact CE1-CG2 3.6Å; Y431-V450 HydrophobicContact CE2-CG1 3.86Å; Y431-V450 HydrophobicContact CE2-CG2 4.35Å; Y431-V450 HydrophobicContact CG-CG2 4.19Å; L447-V450 HydrophobicContact CD1-CG2 4.12Å; L447-V450 HydrophobicContact CD2-CG2 4.11Å
451Q88.2Confident84.1Confident46 Ų4652.6 Ų52.622%0.21528%0.278CS..EExtended strand (participates in β ladder)trans-104.4125.3176.9-178.4170.51200109.6E429 I430 Q502E429-Q451 CarbonylContact C-O 3.59Å; E429-Q451 WeakPolarHBondContact CA-O 3.39Å; I430-Q451 HydrophobicContact CB-CB 4.43Å; I430-Q451 PolarHBondContact N-O 2.67Å; I430-Q451 PolarHBondContact O-N 3.2Å; Q451-Q502 VanDerWaalsContact OE1-NE2 3.09Å
452L90Very high85.6Confident84 Ų8450 Ų5044%0.4427%0.265SS..EExtended strand (participates in β ladder)trans-85.2129.7173.5-171.466.5000109.8E429 R456E429-L452 HydrophobicContact CG-CD1 3.88Å; L452-R456 HydrophobicContact CD1-CG 4.39Å
453L90.1Very high87Confident4 Ų452.1 Ų52.12%0.02128%0.276CS..  trans-76.7160.3174-62.2172.7000110.8G428 I430 S455 V459 V489 Q491 L498G428-L453 VanDerWaalsContact O-CB 3.28Å; G428-L453 WeakPolarHBondContact O-CB 3.43Å; G428-L453 WeakPolarHBondContact O-CG 3.48Å; G428-L453 PolarHBondContact O-N 2.78Å; I430-L453 HydrophobicContact CD1-CD1 4.3Å; I430-L453 HydrophobicContact CG1-CD1 4.3Å; I430-L453 HydrophobicContact CG1-CD2 4.09Å; I430-L453 HydrophobicContact CG1-CG 4.23Å; L453-S455 VanDerWaalsContact C-N 3.26Å; L453-S455 PolarHBondContact O-N 3.22Å; L453-V459 HydrophobicContact CD1-CG2 3.65Å; L453-V489 HydrophobicContact CD1-CG1 3.68Å; L453-V489 HydrophobicContact CD2-CG1 4.42Å; L453-Q491 HydrophobicContact CD1-CG 4.17Å; L453-L498 HydrophobicContact CD2-CD1 3.99Å
454P79.4Confident88Confident89 Ų8950.8 Ų50.858%0.57827%0.27SS*.SBendtrans-57.6-36.3-177.6-24.333.3000113.9H15H15-P454 WeakPolarHBondContact CE1-CG 3.32Å; H15-P454 WeakPolarHBondContact NE2-CG 3.05Å
455S84.6Confident88.3Confident22 Ų2247.2 Ų47.215%0.15425%0.251CS..SBendtrans-105.6140171.665.80000110.6L453 E457 Q491 I493L453-S455 VanDerWaalsContact C-N 3.26Å; L453-S455 PolarHBondContact O-N 3.22Å; S455-E457 PolarHBondContact O-N 3.18Å; S455-Q491 PolarHBondContact O-NE2 2.9Å; S455-Q491 VanDerWaalsContact OG-CD 3.24Å; S455-Q491 PolarHBondContact OG-NE2 3.14Å; S455-Q491 VanDerWaalsContact OG-NE2 3.09Å; S455-Q491 PolarHBondContact OG-OE1 3.19Å; S455-I493 WeakPolarHBondContact OG-CG2 3.3Å
456R90.2Very high87.9Confident200 Ų20049.8 Ų49.876%0.75526%0.259SS*.  trans-82.244.1173.8-62.7-169.2177.2-149.6-0.8111.8N427 L452N427-R456 CarbonylContact O-C 3.4Å; N427-R456 WeakPolarHBondContact O-CA 3.29Å; L452-R456 HydrophobicContact CD1-CG 4.39Å
457E93.7Very high86.9Confident47 Ų4747.2 Ų47.222%0.2225%0.246CC..SBendtrans-104.8156-179.6-69.4-175.3155.800110.8K22 G428 S455 V459 Q491K22-E457 IonicContact NZ-OE1 3.96Å; G428-E457 WeakPolarHBondContact CA-O 3.48Å; G428-E457 PolarHBondContact N-O 2.75Å; S455-E457 PolarHBondContact O-N 3.18Å; E457-V459 PolarHBondContact O-N 3.19Å; E457-Q491 PolarHBondContact O-NE2 2.86Å
458P96.6Very high85.4Confident55 Ų5548.3 Ų48.336%0.35725%0.249SC..  trans-52.8136.9177.4-2430.7000113.2N426 Q460N426-P458 WeakPolarHBondContact O-CA 3.45Å; N426-P458 VanDerWaalsContact O-CG 3.31Å; N426-P458 WeakPolarHBondContact O-CG 3.46Å; P458-Q460 PolarHBondContact O-N 2.86Å
459V97.5Very high84.1Confident3 Ų348.4 Ų48.42%0.01825%0.249CC..  trans-71.1121.2167.2176.80000108.7T404 K405 T425 I430 L453 E457 V462 V489T404-V459 PolarHBondContact OG1-O 2.9Å; K405-V459 HydrophobicContact CB-CG1 4.19Å; K405-V459 HydrophobicContact CG-CG1 4.29Å; T425-V459 PolarHBondContact O-N 3Å; I430-V459 HydrophobicContact CD1-CG2 3.97Å; L453-V459 HydrophobicContact CD1-CG2 3.65Å; E457-V459 PolarHBondContact O-N 3.19Å; V459-V462 HydrophobicContact CG1-CG2 3.47Å; V459-V462 VanDerWaalsContact CG1-CG2 3.47Å; V459-V489 HydrophobicContact CB-CG1 4.46Å; V459-V489 HydrophobicContact CG1-CG1 3.65Å; V459-V489 HydrophobicContact CG2-CG1 4.07Å
460Q96.3Very high82.5Confident47 Ų4750.9 Ų50.922%0.2226%0.262CS..  trans-94.7-37.9-175.3-64-65.8-12.400112.6R26 K405 P458 S490 D492R26-Q460 HydrophobicContact CB-CB 4.49Å; R26-Q460 HydrophobicContact CG-CB 4.22Å; R26-Q460 HydrophobicContact CG-CG 3.98Å; K405-Q460 WeakPolarHBondContact CE-O 3.42Å; P458-Q460 PolarHBondContact O-N 2.86Å; Q460-S490 PolarHBondContact N-O 2.96Å; Q460-D492 PolarHBondContact NE2-OD1 3.09Å
461A95.9Very high80.9Confident13 Ų1348.1 Ų48.111%0.10725%0.246CC..EExtended strand (participates in β ladder)trans-150.4153.9174.300000111.1L28 V489 S490L28-A461 HydrophobicContact CB-CB 4.27Å; L28-A461 HydrophobicContact CD1-CB 3.99Å; L28-A461 HydrophobicContact CG-CB 3.87Å; A461-V489 WeakPolarHBondContact O-CA 3.35Å; A461-S490 WeakPolarHBondContact CB-OG 3.24Å; A461-S490 PolarHBondContact N-OG 3.46Å; A461-S490 PolarHBondContact O-N 2.66Å
462V95.5Very high79Confident8 Ų849.2 Ų49.25%0.04826%0.263CS..EExtended strand (participates in β ladder)trans-137.6123176.9-1750000108.3K405 A407 V459 L487 Y488 V489K405-V462 HydrophobicContact CB-CB 4.38Å; K405-V462 HydrophobicContact CB-CG2 3.71Å; A407-V462 HydrophobicContact CB-CB 4.31Å; A407-V462 HydrophobicContact CB-CG1 3.58Å; V459-V462 HydrophobicContact CG1-CG2 3.47Å; V459-V462 VanDerWaalsContact CG1-CG2 3.47Å; V462-L487 HydrophobicContact CG1-CD1 3.42Å; V462-L487 VanDerWaalsContact CG1-CD1 3.42Å; V462-L487 HydrophobicContact CG1-CD2 4.01Å; V462-L487 HydrophobicContact CG1-CG 3.75Å; V462-Y488 CarbonylContact C-O 3.55Å; V462-Y488 WeakPolarHBondContact CA-O 3.2Å; V462-V489 HydrophobicContact CG1-CG2 4.44Å; V462-V489 HydrophobicContact CG2-CG1 4.44Å
463E92.7Very high77.1Confident51 Ų5148.3 Ų48.324%0.23826%0.255CS..EExtended strand (participates in β ladder)trans-126.7149.5176.4-74.9-63.3166.400110.6L28 L30 L487 Y488L28-E463 HydrophobicContact CB-CG 3.68Å; L28-E463 HydrophobicContact CD1-CB 4.41Å; L28-E463 HydrophobicContact CD1-CG 4.28Å; L30-E463 HydrophobicContact CB-CB 4.26Å; L30-E463 HydrophobicContact CB-CG 4.35Å; L30-E463 HydrophobicContact CD2-CB 4.38Å; E463-L487 CarbonylContact O-C 3.54Å; E463-L487 WeakPolarHBondContact O-CA 3.46Å; E463-Y488 PolarHBondContact N-O 3.2Å; E463-Y488 PolarHBondContact O-N 2.91Å
464L86.8Confident75.1Confident22 Ų2258.1 Ų58.112%0.11530%0.298CS..EExtended strand (participates in β ladder)trans-127.5123-176.4-174.3151.4000110.7L30 A407 D409 Y422 L487 I500L30-L464 VanDerWaalsContact CD2-C 3.42Å; L30-L464 WeakPolarHBondContact CD2-O 3.34Å; A407-L464 HydrophobicContact CB-CB 4.25Å; D409-L464 HydrophobicContact CB-CD1 3.79Å; D409-L464 HydrophobicContact CB-CD2 4.44Å; Y422-L464 HydrophobicContact CD2-CD1 3.91Å; Y422-L464 HydrophobicContact CE2-CD1 3.78Å; L464-L487 HydrophobicContact CB-CD1 4.27Å; L464-L487 HydrophobicContact CD1-CD1 4.33Å; L464-I500 HydrophobicContact CD1-CD1 3.4Å; L464-I500 VanDerWaalsContact CD1-CD1 3.4Å; L464-I500 HydrophobicContact CG-CD1 3.75Å
465L81.8Confident73.7Confident6 Ų663.1 Ų63.13%0.03131%0.311CS..EExtended strand (participates in β ladder)trans-122.3144175.8-165.656.3000112.2L30 Q32 V50 V467 K485 Y486 Y488L30-L465 HydrophobicContact CD1-CB 3.91Å; L30-L465 HydrophobicContact CD1-CD1 4.36Å; L30-L465 HydrophobicContact CD1-CD2 3.77Å; L30-L465 HydrophobicContact CD1-CG 4.17Å; L30-L465 HydrophobicContact CD2-CB 3.43Å; L30-L465 VanDerWaalsContact CD2-CB 3.43Å; L30-L465 HydrophobicContact CD2-CD1 3.77Å; L30-L465 HydrophobicContact CD2-CG 4.03Å; L30-L465 HydrophobicContact CG-CB 4.11Å; L30-L465 HydrophobicContact CG-CD1 4.03Å; L30-L465 HydrophobicContact CG-CD2 4.34Å; L30-L465 HydrophobicContact CG-CG 4.33Å; Q32-L465 HydrophobicContact CB-CD1 3.79Å; Q32-L465 HydrophobicContact CG-CD1 3.83Å; V50-L465 HydrophobicContact CB-CD2 3.85Å; V50-L465 HydrophobicContact CG1-CD2 3.82Å; V50-L465 HydrophobicContact CG2-CD2 3.98Å; L465-V467 HydrophobicContact CB-CG2 4.4Å; L465-V467 HydrophobicContact CD2-CG2 3.74Å; L465-V467 HydrophobicContact CG-CG2 4.02Å; L465-K485 VanDerWaalsContact O-CA 3.28Å; L465-K485 WeakPolarHBondContact O-CA 3.43Å; L465-Y486 PolarHBondContact N-O 3.06Å; L465-Y486 PolarHBondContact O-N 2.86Å; L465-Y488 HydrophobicContact CB-CE2 3.78Å
466Q69.5Low72Confident65 Ų6569.3 Ų69.330%0.30434%0.335SS..EExtended strand (participates in β ladder)trans-95.1115.4160.7-174.3165.8-10.500110.6K485Q466-K485 HydrophobicContact CB-CG 4Å; Q466-K485 HydrophobicContact CG-CG 4.02Å
467V58.4Low70Confident5 Ų565 Ų653%0.0334%0.343CS..EExtended strand (participates in β ladder)trans-104.5129.9-179.9-177.20000109.7V50 E51 L465 I469 E484 Y486V50-V467 HydrophobicContact CB-CG2 4.49Å; V50-V467 HydrophobicContact CG2-CG2 4.28Å; E51-V467 HydrophobicContact CG-CG1 4.15Å; L465-V467 HydrophobicContact CB-CG2 4.4Å; L465-V467 HydrophobicContact CD2-CG2 3.74Å; L465-V467 HydrophobicContact CG-CG2 4.02Å; V467-I469 HydrophobicContact CG1-CG1 4.11Å; V467-E484 PolarHBondContact N-O 3.46Å; V467-E484 PolarHBondContact O-N 3.12Å; V467-Y486 HydrophobicContact CB-CD2 4.39Å; V467-Y486 HydrophobicContact CG2-CD2 4.07Å
468H51Low67.6Low92 Ų9267 Ų6743%0.42636%0.355SS..EExtended strand (participates in β ladder)trans-88.4110.6170.3-69.3-152.4000109.1Q483H468-Q483 VanDerWaalsContact CD2-CD 3.46Å; H468-Q483 PolarHBondContact CD2-NE2 3.07Å; H468-Q483 PolarHBondContact CD2-OE1 2.94Å; H468-Q483 PolarHBondContact CE1-NE2 2.91Å; H468-Q483 VanDerWaalsContact CG-NE2 3.3Å; H468-Q483 PolarHBondContact ND1-NE2 3.38Å; H468-Q483 PolarHBondContact NE2-NE2 3.14Å; H468-Q483 PolarHBondContact NE2-OE1 3.48Å; H468-Q483 VanDerWaalsContact NE2-OE1 3.17Å
469I55.2Low65.1Low43 Ų4370.5 Ų70.522%0.22137%0.369CS..EExtended strand (participates in β ladder)trans-99.3121.1174.4-58.6-179.9000108.5V467 S481 L482 E484 Y486V467-I469 HydrophobicContact CG1-CG1 4.11Å; I469-S481 CarbonylContact O-C 3.56Å; I469-S481 WeakPolarHBondContact O-CA 3.32Å; I469-L482 HydrophobicContact CB-CB 4.37Å; I469-L482 PolarHBondContact N-O 3.1Å; I469-L482 PolarHBondContact O-N 3.1Å; I469-E484 HydrophobicContact CD1-CB 4.11Å; I469-E484 HydrophobicContact CD1-CG 3.89Å; I469-E484 WeakPolarHBondContact CD1-OE2 3.42Å; I469-Y486 HydrophobicContact CD1-CE2 4.49Å
470V51.2Low62.8Low100 Ų10071.4 Ų71.461%0.60637%0.374SS*.EExtended strand (participates in β ladder)trans-98.3102.3175.6-175.70000108.4I479V470-I479 HydrophobicContact CG1-CG2 3.42Å; V470-I479 VanDerWaalsContact CG1-CG2 3.42Å
471C53.8Low60.5Low9 Ų972.4 Ų72.46%0.06139%0.387CS..EExtended strand (participates in β ladder)trans-84.6115.4173.1-71.30000109.4C8 F473 V480C8-C471 HydrophobicContact CB-CB 4.26Å; C8-C471 WeakPolarHBondContact CB-SG 3.15Å; C8-C471 WeakPolarHBondContact SG-CB 3.29Å; C8-C471 CovalentContact SG-SG 2.08Å; C8-C471 PolarHBondContact SG-SG 2.72Å; C471-F473 HydrophobicContact CB-CD2 4.35Å; C471-F473 HydrophobicContact CB-CE2 3.93Å; C471-V480 HydrophobicContact CB-CB 4.39Å; C471-V480 PolarHBondContact N-O 3.44Å; C471-V480 PolarHBondContact O-N 3.48Å
472A48.7Very low58.7Low69 Ų6972.8 Ų72.857%0.5739%0.387SS*.EExtended strand (participates in β ladder)trans-89.9107.2166.300000109.5F474A472-F474 PolarHBondContact O-N 2.86Å
473F49.5Very low57.1Low64 Ų6475 Ų7528%0.28140%0.397SS..  trans-79.6109.5172-74.3-90.8000109.3C8 C471 K475 F476 V480C8-F473 HydrophobicContact CB-CE1 4.43Å; C8-F473 HydrophobicContact CB-CE2 4.48Å; C8-F473 HydrophobicContact CB-CZ 3.8Å; C471-F473 HydrophobicContact CB-CD2 4.35Å; C471-F473 HydrophobicContact CB-CE2 3.93Å; F473-K475 PolarHBondContact O-N 3.02Å; F473-F476 WeakPolarHBondContact CB-O 3.49Å; F473-F476 CarbonylContact O-C 3.53Å; F473-V480 HydrophobicContact CD2-CB 4.42Å; F473-V480 HydrophobicContact CD2-CG2 3.85Å; F473-V480 HydrophobicContact CE2-CB 3.95Å; F473-V480 HydrophobicContact CE2-CG2 3.56Å
474F49.2Very low56.2Low210 Ų21073.7 Ų73.792%0.92139%0.391SS*.THydrogen-bonded Turntrans-67.9-17.7178.3-88.2-86.1000114.1A472A472-F474 PolarHBondContact O-N 2.86Å
475K50.1Low56.2Low194 Ų19474.6 Ų74.684%0.84339%0.394SS*.THydrogen-bonded Turntrans-89.4-22.9-179.6-81.5-167.1176.1-176.90115F473F473-K475 PolarHBondContact O-N 3.02Å
476F48.4Very low56.6Low153 Ų15374.8 Ų74.867%0.67139%0.394SS*.SBendtrans-141.2119.5174.6-60-79.9000105.1F473 N478F473-F476 WeakPolarHBondContact CB-O 3.49Å; F473-F476 CarbonylContact O-C 3.53Å; F476-N478 PolarHBondContact O-N 3.33Å
477A47.3Very low57.8Low110 Ų11071.9 Ų71.991%0.90938%0.38SS*.  trans-64.553-177.400000113.6
478N43.2Very low59.6Low89 Ų8971.6 Ų71.648%0.47638%0.379SS..  trans-113.2103173.9-74.2-44.8000106.6F476 V480F476-N478 PolarHBondContact O-N 3.33Å; N478-V480 PolarHBondContact O-N 2.85Å
479I46Very low61.7Low127 Ų12767.2 Ų67.265%0.65136%0.359SS*.EExtended strand (participates in β ladder)trans-67.8119.5165.4-63.1173.3000106.7V470V470-I479 HydrophobicContact CG1-CG2 3.42Å; V470-I479 VanDerWaalsContact CG1-CG2 3.42Å
480V49.1Very low63.7Low22 Ų2265.2 Ų65.213%0.13335%0.348CS..EExtended strand (participates in β ladder)trans-103.6112.2173.9-177.10000107.6C471 F473 N478 L482C471-V480 HydrophobicContact CB-CB 4.39Å; C471-V480 PolarHBondContact N-O 3.44Å; C471-V480 PolarHBondContact O-N 3.48Å; F473-V480 HydrophobicContact CD2-CB 4.42Å; F473-V480 HydrophobicContact CD2-CG2 3.85Å; F473-V480 HydrophobicContact CE2-CB 3.95Å; F473-V480 HydrophobicContact CE2-CG2 3.56Å; N478-V480 PolarHBondContact O-N 2.85Å; V480-L482 HydrophobicContact CG1-CD2 3.73Å; V480-L482 HydrophobicContact CG1-CG 3.93Å; V480-L482 PolarHBondContact O-N 2.96Å
481S47.9Very low65.9Low68 Ų6860.5 Ų60.548%0.47632%0.32SS..EExtended strand (participates in β ladder)trans-83.3107.6168.6-174.40000108.5I469I469-S481 CarbonylContact O-C 3.56Å; I469-S481 WeakPolarHBondContact O-CA 3.32Å
482L58Low67.9Low22 Ų2260.8 Ų60.812%0.11532%0.321CS..EExtended strand (participates in β ladder)trans-94.5129.2172.5-64.4175.6000109I469 V480 E484I469-L482 HydrophobicContact CB-CB 4.37Å; I469-L482 PolarHBondContact N-O 3.1Å; I469-L482 PolarHBondContact O-N 3.1Å; V480-L482 HydrophobicContact CG1-CD2 3.73Å; V480-L482 HydrophobicContact CG1-CG 3.93Å; V480-L482 PolarHBondContact O-N 2.96Å; L482-E484 HydrophobicContact CB-CG 4.37Å
483Q61.9Low70.1Confident54 Ų5460.2 Ų60.225%0.25231%0.308SS..EExtended strand (participates in β ladder)trans-99.194.6175.3-69.5-89.5-1900106.7H468 K531H468-Q483 VanDerWaalsContact CD2-CD 3.46Å; H468-Q483 PolarHBondContact CD2-NE2 3.07Å; H468-Q483 PolarHBondContact CD2-OE1 2.94Å; H468-Q483 PolarHBondContact CE1-NE2 2.91Å; H468-Q483 VanDerWaalsContact CG-NE2 3.3Å; H468-Q483 PolarHBondContact ND1-NE2 3.38Å; H468-Q483 PolarHBondContact NE2-NE2 3.14Å; H468-Q483 PolarHBondContact NE2-OE1 3.48Å; H468-Q483 VanDerWaalsContact NE2-OE1 3.17Å; Q483-K531 HydrophobicContact CB-CD 4.22Å; Q483-K531 VanDerWaalsContact CB-NZ 3.25Å
484E74.1Confident72.3Confident23 Ų2357.2 Ų57.211%0.10729%0.294CS..EExtended strand (participates in β ladder)trans-100.4137.6-179.3-65.7-157.7146.100110.4V467 I469 L482 Y486 R529V467-E484 PolarHBondContact N-O 3.46Å; V467-E484 PolarHBondContact O-N 3.12Å; I469-E484 HydrophobicContact CD1-CB 4.11Å; I469-E484 HydrophobicContact CD1-CG 3.89Å; I469-E484 WeakPolarHBondContact CD1-OE2 3.42Å; L482-E484 HydrophobicContact CB-CG 4.37Å; E484-Y486 HydrophobicContact CB-CD2 4.38Å; E484-Y486 HydrophobicContact CB-CE2 3.71Å; E484-Y486 VanDerWaalsContact OE2-CZ 3.28Å; E484-Y486 PolarHBondContact OE2-OH 3.38Å; E484-R529 IonicContact OE1-CZ 3.84Å; E484-R529 IonicContact OE1-NH1 2.86Å; E484-R529 PolarHBondContact OE1-NH1 2.67Å; E484-R529 IonicContact OE1-NH2 3.78Å
485K85.9Confident74.6Confident42 Ų4247.2 Ų47.218%0.18325%0.25CS..EExtended strand (participates in β ladder)trans-106.9135.8172.5-60.1-170.8174.8-177.20110D409 L465 Q466 I500D409-K485 IonicContact OD1-NZ 3.08Å; D409-K485 PolarHBondContact OD1-NZ 3.31Å; D409-K485 VanDerWaalsContact OD2-CD 3.31Å; D409-K485 WeakPolarHBondContact OD2-CD 3.11Å; D409-K485 IonicContact OD2-NZ 2.67Å; D409-K485 PolarHBondContact OD2-NZ 2.08Å; L465-K485 VanDerWaalsContact O-CA 3.28Å; L465-K485 WeakPolarHBondContact O-CA 3.43Å; Q466-K485 HydrophobicContact CB-CG 4Å; Q466-K485 HydrophobicContact CG-CG 4.02Å; K485-I500 HydrophobicContact CB-CB 4.27Å; K485-I500 HydrophobicContact CB-CD1 3.86Å; K485-I500 PolarHBondContact O-N 3.05Å; K485-I500 VanDerWaalsContact O-N 3.14Å
486Y90.8Very high76.7Confident9 Ų938 Ų384%0.03521%0.21CC..EExtended strand (participates in β ladder)trans-122.8139.7179.6-70.5-82.5000110.1L465 V467 I469 E484 Q497 L498 A499L465-Y486 PolarHBondContact N-O 3.06Å; L465-Y486 PolarHBondContact O-N 2.86Å; V467-Y486 HydrophobicContact CB-CD2 4.39Å; V467-Y486 HydrophobicContact CG2-CD2 4.07Å; I469-Y486 HydrophobicContact CD1-CE2 4.49Å; E484-Y486 HydrophobicContact CB-CD2 4.38Å; E484-Y486 HydrophobicContact CB-CE2 3.71Å; E484-Y486 VanDerWaalsContact OE2-CZ 3.28Å; E484-Y486 PolarHBondContact OE2-OH 3.38Å; Y486-Q497 HydrophobicContact CD1-CG 3.5Å; Y486-Q497 VanDerWaalsContact CD1-CG 3.5Å; Y486-Q497 HydrophobicContact CE1-CG 4.09Å; Y486-Q497 HydrophobicContact CG-CG 4.01Å; Y486-L498 CarbonylContact C-O 3.52Å; Y486-L498 VanDerWaalsContact CA-O 3.3Å; Y486-L498 WeakPolarHBondContact CA-O 3.4Å; Y486-A499 HydrophobicContact CD1-CB 4.46Å; Y486-A499 HydrophobicContact CE1-CB 4.2Å
487L93.8Very high78.9Confident4 Ų430.8 Ų30.82%0.02118%0.179CC..EExtended strand (participates in β ladder)trans-96.3124.6166.4-163.974.1000108.1A407 Y422 I430 V462 E463 L464 V489 L498 I500A407-L487 HydrophobicContact CB-CD1 4.03Å; Y422-L487 HydrophobicContact CD1-CD2 3.99Å; Y422-L487 HydrophobicContact CD2-CD1 4.05Å; Y422-L487 HydrophobicContact CG-CD1 3.92Å; Y422-L487 HydrophobicContact CG-CD2 3.99Å; I430-L487 HydrophobicContact CG2-CD2 3.96Å; V462-L487 HydrophobicContact CG1-CD1 3.42Å; V462-L487 VanDerWaalsContact CG1-CD1 3.42Å; V462-L487 HydrophobicContact CG1-CD2 4.01Å; V462-L487 HydrophobicContact CG1-CG 3.75Å; E463-L487 CarbonylContact O-C 3.54Å; E463-L487 WeakPolarHBondContact O-CA 3.46Å; L464-L487 HydrophobicContact CB-CD1 4.27Å; L464-L487 HydrophobicContact CD1-CD1 4.33Å; L487-V489 HydrophobicContact CD2-CG2 3.7Å; L487-V489 HydrophobicContact CG-CG2 3.87Å; L487-L498 HydrophobicContact CB-CB 4.28Å; L487-L498 HydrophobicContact CD2-CD1 4.44Å; L487-L498 PolarHBondContact N-O 3.32Å; L487-L498 PolarHBondContact O-N 2.88Å; L487-I500 HydrophobicContact CB-CD1 4.49Å; L487-I500 HydrophobicContact CB-CG1 4.22Å
488Y95.6Very high81Confident0 Ų025.7 Ų25.70%014%0.136CC..EExtended strand (participates in β ladder)trans-101.8119.6172.5-57.4-86.5000108.1L30 L37 V50 V53 V462 E463 L465 S496 Q497L30-Y488 HydrophobicContact CD1-CD2 4.34Å; L30-Y488 HydrophobicContact CD1-CE2 4.2Å; L37-Y488 HydrophobicContact CD1-CG 4.48Å; L37-Y488 HydrophobicContact CD2-CD1 3.57Å; L37-Y488 HydrophobicContact CD2-CE1 4.22Å; L37-Y488 HydrophobicContact CD2-CG 3.86Å; V50-Y488 WeakPolarHBondContact CA-OH 3.3Å; V50-Y488 WeakPolarHBondContact CB-OH 3.43Å; V50-Y488 PolarHBondContact O-OH 3.09Å; V53-Y488 HydrophobicContact CG1-CD1 3.96Å; V53-Y488 HydrophobicContact CG1-CE1 3.72Å; V462-Y488 CarbonylContact C-O 3.55Å; V462-Y488 WeakPolarHBondContact CA-O 3.2Å; E463-Y488 PolarHBondContact N-O 3.2Å; E463-Y488 PolarHBondContact O-N 2.91Å; L465-Y488 HydrophobicContact CB-CE2 3.78Å; Y488-S496 CarbonylContact C-O 3.52Å; Y488-S496 VanDerWaalsContact CA-O 3.32Å; Y488-S496 WeakPolarHBondContact CA-O 3.38Å; Y488-Q497 HydrophobicContact CD1-CB 3.98Å; Y488-Q497 HydrophobicContact CD1-CG 4.22Å; Y488-Q497 HydrophobicContact CE1-CB 3.94Å; Y488-Q497 HydrophobicContact CE1-CG 3.74Å
489V96.6Very high83Confident0 Ų021.9 Ų21.90%012%0.117CC..EExtended strand (participates in β ladder)trans-121.9124-175.3-176.70000108.3I430 L453 V459 A461 V462 L487 V495 S496 L498I430-V489 HydrophobicContact CD1-CG1 3.96Å; I430-V489 HydrophobicContact CD1-CG2 4.01Å; I430-V489 HydrophobicContact CG1-CG2 4.35Å; L453-V489 HydrophobicContact CD1-CG1 3.68Å; L453-V489 HydrophobicContact CD2-CG1 4.42Å; V459-V489 HydrophobicContact CB-CG1 4.46Å; V459-V489 HydrophobicContact CG1-CG1 3.65Å; V459-V489 HydrophobicContact CG2-CG1 4.07Å; A461-V489 WeakPolarHBondContact O-CA 3.35Å; V462-V489 HydrophobicContact CG1-CG2 4.44Å; V462-V489 HydrophobicContact CG2-CG1 4.44Å; L487-V489 HydrophobicContact CD2-CG2 3.7Å; L487-V489 HydrophobicContact CG-CG2 3.87Å; V489-V495 CarbonylContact O-C 3.48Å; V489-V495 WeakPolarHBondContact O-CA 3.36Å; V489-S496 PolarHBondContact N-O 2.92Å; V489-S496 PolarHBondContact O-N 3.19Å; V489-L498 HydrophobicContact CG2-CD1 4Å
490S96.5Very high84.9Confident0 Ų016.7 Ų16.70%09%0.09CC..EExtended strand (participates in β ladder)trans-102.9144.7176.681.90000112.3Y25 Q460 A461 G494Y25-S490 WeakPolarHBondContact O-CB 3.29Å; Y25-S490 PolarHBondContact O-OG 2.71Å; Q460-S490 PolarHBondContact N-O 2.96Å; A461-S490 WeakPolarHBondContact CB-OG 3.24Å; A461-S490 PolarHBondContact N-OG 3.46Å; A461-S490 PolarHBondContact O-N 2.66Å; S490-G494 WeakPolarHBondContact CA-O 3.28Å
491Q96.8Very high86.5Confident1 Ų116.5 Ų16.51%0.0059%0.091CC..EExtended strand (participates in β ladder)trans-134.2167.3171.8-63.4176.6-7800107.5Y25 L453 S455 E457 I493 G494Y25-Q491 WeakPolarHBondContact CB-O 3.37Å; L453-Q491 HydrophobicContact CD1-CG 4.17Å; S455-Q491 PolarHBondContact O-NE2 2.9Å; S455-Q491 VanDerWaalsContact OG-CD 3.24Å; S455-Q491 PolarHBondContact OG-NE2 3.14Å; S455-Q491 VanDerWaalsContact OG-NE2 3.09Å; S455-Q491 PolarHBondContact OG-OE1 3.19Å; E457-Q491 PolarHBondContact O-NE2 2.86Å; Q491-I493 HydrophobicContact CB-CG2 4.29Å; Q491-I493 PolarHBondContact O-N 3.38Å; Q491-G494 PolarHBondContact N-O 2.87Å; Q491-G494 PolarHBondContact O-N 2.93Å; Q491-G494 VanDerWaalsContact O-O 3.12Å
492D96Very high88Confident16 Ų1616.3 Ų16.39%0.0868%0.083CC..THydrogen-bonded Turntrans-60.2-21.2-178.2-73.7-19.4000113.1L23 Y24 R26 Q460L23-D492 PolarHBondContact N-O 3.39Å; Y24-D492 WeakPolarHBondContact CA-O 3.39Å; Y24-D492 HydrophobicContact CD1-CB 3.9Å; Y24-D492 WeakPolarHBondContact CD1-OD2 2.99Å; Y24-D492 HydrophobicContact CE1-CB 4.34Å; Y24-D492 HydrophobicContact CG-CB 4.48Å; Y24-D492 PolarHBondContact N-O 3.28Å; R26-D492 IonicContact CZ-OD1 3.69Å; R26-D492 IonicContact NE-OD1 3.59Å; R26-D492 PolarHBondContact NE-OD1 3.41Å; R26-D492 IonicContact NH2-OD1 2.73Å; R26-D492 IonicContact NH2-OD2 3.25Å; Q460-D492 PolarHBondContact NE2-OD1 3.09Å
493I95.7Very high89.1Confident57 Ų5715.3 Ų15.329%0.2928%0.078SC..THydrogen-bonded Turntrans-91.2-18.3178-163.7149.9000115.5F17 S19 Y25 S455 Q491F17-I493 HydrophobicContact CZ-CG2 4.17Å; S19-I493 VanDerWaalsContact CB-O 3.22Å; S19-I493 WeakPolarHBondContact CB-O 3.35Å; S19-I493 PolarHBondContact OG-O 2.82Å; Y25-I493 WeakPolarHBondContact CE2-O 3.36Å; S455-I493 WeakPolarHBondContact OG-CG2 3.3Å; Q491-I493 HydrophobicContact CB-CG2 4.29Å; Q491-I493 PolarHBondContact O-N 3.38Å
494G96Very high89.8Confident0 Ų016.8 Ų16.80%09%0.087CC..EExtended strand (participates in β ladder)trans166.8-172-178.200000115.4F18 S490 Q491F18-G494 CarbonylContact O-C 3.49Å; F18-G494 WeakPolarHBondContact O-CA 3.14Å; S490-G494 WeakPolarHBondContact CA-O 3.28Å; Q491-G494 PolarHBondContact N-O 2.87Å; Q491-G494 PolarHBondContact O-N 2.93Å; Q491-G494 VanDerWaalsContact O-O 3.12Å
495V96.8Very high89.9Confident0 Ų019.5 Ų19.50%011%0.105CC..EExtended strand (participates in β ladder)trans-119.2119.9-179.2-177.10000110.1F17 F18 Y25 L28 L37 V39 V489F17-V495 WeakPolarHBondContact CA-O 3.46Å; F17-V495 WeakPolarHBondContact CD2-O 3.33Å; F18-V495 PolarHBondContact N-O 2.93Å; F18-V495 PolarHBondContact O-N 2.8Å; Y25-V495 HydrophobicContact CD1-CG2 4.34Å; Y25-V495 HydrophobicContact CG-CG2 4.39Å; L28-V495 HydrophobicContact CD2-CG1 4.45Å; L28-V495 HydrophobicContact CD2-CG2 4.17Å; L37-V495 HydrophobicContact CD2-CG1 4.07Å; V39-V495 HydrophobicContact CG1-CG2 3.79Å; V39-V495 HydrophobicContact CG2-CG2 4.26Å; V489-V495 CarbonylContact O-C 3.48Å; V489-V495 WeakPolarHBondContact O-CA 3.36Å
496S95.2Very high89.5Confident0 Ų019.7 Ų19.70%011%0.108CC..EExtended strand (participates in β ladder)trans-92133.1173.4-66.20000110.8H15 R16 Y488 V489H15-S496 WeakPolarHBondContact NE2-CB 3.11Å; H15-S496 PolarHBondContact NE2-OG 3.48Å; R16-S496 CarbonylContact O-C 3.48Å; R16-S496 WeakPolarHBondContact O-CA 3.46Å; Y488-S496 CarbonylContact C-O 3.52Å; Y488-S496 VanDerWaalsContact CA-O 3.32Å; Y488-S496 WeakPolarHBondContact CA-O 3.38Å; V489-S496 PolarHBondContact N-O 2.92Å; V489-S496 PolarHBondContact O-N 3.19Å
497Q93.3Very high88.7Confident2 Ų225.7 Ų25.71%0.00913%0.131CC..EExtended strand (participates in β ladder)trans-105.8115.4167.2169.4-17727.800108.5R16 V50 V53 Y486 Y488R16-Q497 HydrophobicContact CB-CB 4.06Å; R16-Q497 PolarHBondContact N-O 2.87Å; R16-Q497 VanDerWaalsContact N-O 3.08Å; R16-Q497 PolarHBondContact O-N 2.86Å; V50-Q497 PolarHBondContact O-NE2 2.81Å; V53-Q497 HydrophobicContact CB-CB 4.49Å; V53-Q497 HydrophobicContact CG1-CB 4.01Å; V53-Q497 HydrophobicContact CG2-CB 3.63Å; V53-Q497 VanDerWaalsContact N-OE1 3.16Å; Y486-Q497 HydrophobicContact CD1-CG 3.5Å; Y486-Q497 VanDerWaalsContact CD1-CG 3.5Å; Y486-Q497 HydrophobicContact CE1-CG 4.09Å; Y486-Q497 HydrophobicContact CG-CG 4.01Å; Y488-Q497 HydrophobicContact CD1-CB 3.98Å; Y488-Q497 HydrophobicContact CD1-CG 4.22Å; Y488-Q497 HydrophobicContact CE1-CB 3.94Å; Y488-Q497 HydrophobicContact CE1-CG 3.74Å
498L91.1Very high87.8Confident3 Ų326 Ų262%0.01613%0.133CC..EExtended strand (participates in β ladder)trans-113.3130-175.6-49.7179.7000110.1H15 I430 L453 Y486 L487 V489 I500H15-L498 WeakPolarHBondContact CD2-CD2 3.15Å; I430-L498 HydrophobicContact CG1-CD1 4.39Å; L453-L498 HydrophobicContact CD2-CD1 3.99Å; Y486-L498 CarbonylContact C-O 3.52Å; Y486-L498 VanDerWaalsContact CA-O 3.3Å; Y486-L498 WeakPolarHBondContact CA-O 3.4Å; L487-L498 HydrophobicContact CB-CB 4.28Å; L487-L498 HydrophobicContact CD2-CD1 4.44Å; L487-L498 PolarHBondContact N-O 3.32Å; L487-L498 PolarHBondContact O-N 2.88Å; V489-L498 HydrophobicContact CG2-CD1 4Å; L498-I500 PolarHBondContact O-N 2.93Å
499A87Confident86.8Confident9 Ų926.8 Ų26.87%0.07414%0.138CC..EExtended strand (participates in β ladder)trans-71127.2170.400000109.7Y486 Q502Y486-A499 HydrophobicContact CD1-CB 4.46Å; Y486-A499 HydrophobicContact CE1-CB 4.2Å; A499-Q502 WeakPolarHBondContact O-CG 3.38Å; A499-Q502 PolarHBondContact O-NE2 2.8Å
500I85.9Confident85.7Confident18 Ų1828 Ų289%0.09215%0.146CC..SBendtrans-69-43.3-179.6-80.5175.7000111.6Y422 L464 K485 L487 L498 Q502 Y517Y422-I500 HydrophobicContact CE1-CG1 4.34Å; Y422-I500 HydrophobicContact CE2-CD1 3.94Å; Y422-I500 HydrophobicContact CE2-CG1 4.32Å; Y422-I500 WeakPolarHBondContact OH-CG2 3.41Å; L464-I500 HydrophobicContact CD1-CD1 3.4Å; L464-I500 VanDerWaalsContact CD1-CD1 3.4Å; L464-I500 HydrophobicContact CG-CD1 3.75Å; K485-I500 HydrophobicContact CB-CB 4.27Å; K485-I500 HydrophobicContact CB-CD1 3.86Å; K485-I500 PolarHBondContact O-N 3.05Å; K485-I500 VanDerWaalsContact O-N 3.14Å; L487-I500 HydrophobicContact CB-CD1 4.49Å; L487-I500 HydrophobicContact CB-CG1 4.22Å; L498-I500 PolarHBondContact O-N 2.93Å; I500-Q502 PolarHBondContact O-N 3.3Å; I500-Q502 VanDerWaalsContact O-N 3.13Å; I500-Y517 HydrophobicContact CG2-CD1 4.18Å; I500-Y517 HydrophobicContact CG2-CD2 3.73Å; I500-Y517 HydrophobicContact CG2-CE1 3.94Å; I500-Y517 HydrophobicContact CG2-CE2 3.47Å; I500-Y517 VanDerWaalsContact CG2-CE2 3.47Å; I500-Y517 HydrophobicContact CG2-CG 4.07Å
501A81.9Confident84.8Confident19 Ų1929.3 Ų29.316%0.15716%0.155CC..  trans-84.987.4-178.700000111.2C503 R529A501-C503 VanDerWaalsContact C-N 3.32Å; A501-C503 PolarHBondContact O-N 2.74Å; A501-R529 HydrophobicContact CB-CG 4.12Å
502Q79.6Confident84Confident64 Ų6429.3 Ų29.330%0.29916%0.155SC..  trans-93.743.8177-60.1-176.7-1.400112.7Q451 A499 I500 D504 V505Q451-Q502 VanDerWaalsContact OE1-NE2 3.09Å; A499-Q502 WeakPolarHBondContact O-CG 3.38Å; A499-Q502 PolarHBondContact O-NE2 2.8Å; I500-Q502 PolarHBondContact O-N 3.3Å; I500-Q502 VanDerWaalsContact O-N 3.13Å; Q502-D504 PolarHBondContact O-N 3.38Å; Q502-V505 HydrophobicContact CB-CG2 4.34Å; Q502-V505 PolarHBondContact O-N 3.37Å; Q502-V505 VanDerWaalsContact O-N 3.12Å
503C81.9Confident83.1Confident0 Ų028.8 Ų28.80%015%0.153CC..G310 helixtrans-59.9-32.7-174.1-51.80000113.2A501 V505 L506 C518 C527 R529A501-C503 VanDerWaalsContact C-N 3.32Å; A501-C503 PolarHBondContact O-N 2.74Å; C503-V505 PolarHBondContact O-N 3.41Å; C503-V505 VanDerWaalsContact O-N 3.08Å; C503-L506 WeakPolarHBondContact O-CB 3.46Å; C503-L506 PolarHBondContact O-N 2.94Å; C503-C518 WeakPolarHBondContact CA-SG 3.25Å; C503-C518 HydrophobicContact CB-CB 3.85Å; C503-C518 WeakPolarHBondContact CB-SG 3.36Å; C503-C518 WeakPolarHBondContact SG-CA 3.46Å; C503-C518 WeakPolarHBondContact SG-CB 3.49Å; C503-C518 CovalentContact SG-SG 2.04Å; C503-C518 PolarHBondContact SG-SG 3.44Å; C503-C527 HydrophobicContact CB-CB 4.5Å; C503-C527 WeakPolarHBondContact O-CB 3.26Å; C503-R529 HydrophobicContact CB-CG 4.44Å
504D76.4Confident82.3Confident85 Ų8529.5 Ų29.546%0.45516%0.155SC..G310 helixtrans-62.1-19.7179.6-53.2-27.1000113.6Q502Q502-D504 PolarHBondContact O-N 3.38Å
505V75Confident81.7Confident81 Ų8130.2 Ų30.249%0.49116%0.16SC..G310 helixtrans-84.6-22.9177.6-174.20000111.2Q502 C503 R507Q502-V505 HydrophobicContact CB-CG2 4.34Å; Q502-V505 PolarHBondContact O-N 3.37Å; Q502-V505 VanDerWaalsContact O-N 3.12Å; C503-V505 PolarHBondContact O-N 3.41Å; C503-V505 VanDerWaalsContact O-N 3.08Å; V505-R507 PolarHBondContact O-N 3.04Å
506L78Confident81Confident46 Ų4630.6 Ų30.624%0.24116%0.163CC..  trans-82.4105.7-177.1-55.4175.3000109.5C503 C512 C518 C527C503-L506 WeakPolarHBondContact O-CB 3.46Å; C503-L506 PolarHBondContact O-N 2.94Å; L506-C512 HydrophobicContact CB-CB 4.43Å; L506-C518 HydrophobicContact CD1-CB 4.31Å; L506-C527 HydrophobicContact CB-CB 4.05Å; L506-C527 WeakPolarHBondContact O-CB 3.49Å
507R74.5Confident80.4Confident134 Ų13431.8 Ų31.851%0.50617%0.167SC..  trans-93.7-6.5-172.3-64.8-169.7177.2169.61.2114.9V505 W520 Y573 E607V505-R507 PolarHBondContact O-N 3.04Å; R507-W520 WeakPolarHBondContact O-CH2 3.28Å; R507-Y573 HydrophobicContact CB-CD1 3.95Å; R507-Y573 HydrophobicContact CB-CG 4.46Å; R507-Y573 VanDerWaalsContact O-CB 3.26Å; R507-Y573 WeakPolarHBondContact O-CB 3.5Å; R507-E607 IonicContact NH1-OE1 2.81Å; R507-E607 IonicContact NH1-OE2 3.88Å; R507-E607 PolarHBondContact NH1-OE2 2.75Å; R507-E607 VanDerWaalsContact NH1-OE2 3.08Å
508S73.4Confident80Confident11 Ų1131.7 Ų31.78%0.07717%0.167CC..SBendtrans-126.515218066.20000112.5T510 S511 C512 W520 Y573S508-T510 VanDerWaalsContact C-N 3.31Å; S508-T510 PolarHBondContact O-N 2.8Å; S508-T510 PolarHBondContact OG-OG1 3.34Å; S508-S511 PolarHBondContact N-OG 3.1Å; S508-S511 PolarHBondContact O-N 2.61Å; S508-S511 PolarHBondContact O-OG 2.87Å; S508-S511 VanDerWaalsContact OG-CB 3.3Å; S508-S511 WeakPolarHBondContact OG-CB 3.28Å; S508-S511 PolarHBondContact OG-N 3.12Å; S508-S511 PolarHBondContact OG-OG 2.92Å; S508-C512 VanDerWaalsContact O-CB 3.28Å; S508-C512 WeakPolarHBondContact O-CB 3.27Å; S508-C512 PolarHBondContact O-N 3.18Å; S508-W520 VanDerWaalsContact C-CZ3 3.49Å; S508-Y573 WeakPolarHBondContact CB-O 3.36Å
509C75.4Confident79.5Confident16 Ų1631.7 Ų31.711%0.10817%0.168CC..Hα-helixtrans-50.5-47.9172.6147.70000112.5C512 A513 W520 C551 V552C509-C512 PolarHBondContact O-N 3.13Å; C509-A513 VanDerWaalsContact O-CB 3.31Å; C509-A513 WeakPolarHBondContact O-CB 3.36Å; C509-A513 PolarHBondContact O-N 2.9Å; C509-W520 HydrophobicContact CB-CD2 3.9Å; C509-W520 HydrophobicContact CB-CG 3.93Å; C509-W520 HydrophobicContact CB-CZ2 4.34Å; C509-C551 HydrophobicContact CB-CB 3.92Å; C509-C551 WeakPolarHBondContact CB-SG 3.31Å; C509-C551 WeakPolarHBondContact SG-CB 3.3Å; C509-C551 CovalentContact SG-SG 2.02Å; C509-C551 PolarHBondContact SG-SG 2.96Å; C509-V552 PolarHBondContact SG-N 3.46Å
510T74.5Confident79.1Confident25 Ų2531.6 Ų31.615%0.15317%0.165CC..Hα-helixtrans-64.2-44.1-179.151.30000111.7S508 Q514 P549 V552 L644S508-T510 VanDerWaalsContact C-N 3.31Å; S508-T510 PolarHBondContact O-N 2.8Å; S508-T510 PolarHBondContact OG-OG1 3.34Å; T510-Q514 VanDerWaalsContact O-CG 3.31Å; T510-Q514 WeakPolarHBondContact O-CG 3.5Å; T510-Q514 PolarHBondContact O-N 3.16Å; T510-P549 HydrophobicContact CG2-CG 4.24Å; T510-V552 HydrophobicContact CG2-CG2 3.58Å; T510-L644 HydrophobicContact CG2-CD2 4.38Å
511S75.7Confident78.6Confident29 Ų2930.8 Ų30.820%0.20316%0.161CC..Hα-helixtrans-65.5-38.4175.1660000112.9S508S508-S511 PolarHBondContact N-OG 3.1Å; S508-S511 PolarHBondContact O-N 2.61Å; S508-S511 PolarHBondContact O-OG 2.87Å; S508-S511 VanDerWaalsContact OG-CB 3.3Å; S508-S511 WeakPolarHBondContact OG-CB 3.28Å; S508-S511 PolarHBondContact OG-N 3.12Å; S508-S511 PolarHBondContact OG-OG 2.92Å
512C80.2Confident78.1Confident0 Ų031.5 Ų31.50%017%0.165CC..Hα-helixtrans-67.3-45.2-178.5-172.30000111.5L506 S508 C509 Q514 S515 W520 C527L506-C512 HydrophobicContact CB-CB 4.43Å; S508-C512 VanDerWaalsContact O-CB 3.28Å; S508-C512 WeakPolarHBondContact O-CB 3.27Å; S508-C512 PolarHBondContact O-N 3.18Å; C509-C512 PolarHBondContact O-N 3.13Å; C512-Q514 PolarHBondContact O-N 3.05Å; C512-S515 PolarHBondContact O-N 3.36Å; C512-W520 HydrophobicContact CB-CB 4.32Å; C512-W520 HydrophobicContact CB-CE3 3.75Å; C512-C527 VanDerWaalsContact CA-SG 3.58Å; C512-C527 HydrophobicContact CB-CB 3.7Å; C512-C527 WeakPolarHBondContact CB-SG 3.48Å; C512-C527 VanDerWaalsContact SG-CA 3.56Å; C512-C527 WeakPolarHBondContact SG-CB 3.18Å; C512-C527 CovalentContact SG-SG 2.03Å; C512-C527 PolarHBondContact SG-SG 3.01Å
513A78.2Confident77.6Confident5 Ų533.6 Ų33.64%0.04118%0.177CC..Hα-helixtrans-70.3-16.9-177.900000114C509 S515 P549C509-A513 VanDerWaalsContact O-CB 3.31Å; C509-A513 WeakPolarHBondContact O-CB 3.36Å; C509-A513 PolarHBondContact O-N 2.9Å; A513-S515 VanDerWaalsContact C-N 3.31Å; A513-P549 HydrophobicContact CB-CB 3.58Å; A513-P549 HydrophobicContact CB-CG 3.88Å
514Q78.5Confident77.1Confident73 Ų7339.5 Ų39.534%0.34120%0.199SC..THydrogen-bonded Turntrans-74.7-21.2173.9-72.61745.100113.2L448 T510 C512 P546L448-Q514 HydrophobicContact CD2-CB 3.67Å; T510-Q514 VanDerWaalsContact O-CG 3.31Å; T510-Q514 WeakPolarHBondContact O-CG 3.5Å; T510-Q514 PolarHBondContact O-N 3.16Å; C512-Q514 PolarHBondContact O-N 3.05Å; Q514-P546 HydrophobicContact CG-CB 4.36Å
515S83.3Confident76.9Confident14 Ų1437.3 Ų37.310%0.09819%0.186CC..SBendtrans-94.1119.7177.9177.90000110.7C512 A513 Y517 C518C512-S515 PolarHBondContact O-N 3.36Å; A513-S515 VanDerWaalsContact C-N 3.31Å; S515-Y517 PolarHBondContact O-N 2.88Å; S515-Y517 VanDerWaalsContact O-N 3.07Å; S515-C518 PolarHBondContact O-N 3.03Å; S515-C518 PolarHBondContact OG-SG 2.88Å
516P81.4Confident77.1Confident9 Ų937.7 Ų37.76%0.05819%0.185CC..THydrogen-bonded Turntrans-67.4-10.617928.2-34.9000113.3P411 V413 F418 V420P411-P516 HydrophobicContact CB-CB 4.18Å; P411-P516 HydrophobicContact CB-CG 4.37Å; P411-P516 HydrophobicContact CG-CB 3.81Å; P411-P516 HydrophobicContact CG-CG 3.57Å; V413-P516 HydrophobicContact CG2-CB 3.96Å; F418-P516 HydrophobicContact CB-CB 3.79Å; F418-P516 HydrophobicContact CB-CG 4.11Å; F418-P516 HydrophobicContact CG-CB 4.24Å; V420-P516 HydrophobicContact CG2-CG 3.48Å; V420-P516 VanDerWaalsContact CG2-CG 3.48Å
517Y84Confident77.2Confident24 Ų2435.8 Ų35.89%0.09418%0.175CC..THydrogen-bonded Turntrans-88.5-9176.8-51.8-71.3000113.4D409 P411 V420 Y422 I500 S515 R529 T530D409-Y517 VanDerWaalsContact CB-OH 3.26Å; D409-Y517 WeakPolarHBondContact CB-OH 3.1Å; D409-Y517 VanDerWaalsContact CG-OH 3.3Å; D409-Y517 VanDerWaalsContact OD2-CE1 3.29Å; D409-Y517 WeakPolarHBondContact OD2-CE1 3.36Å; D409-Y517 PolarHBondContact OD2-OH 2.83Å; P411-Y517 HydrophobicContact CB-CE1 3.96Å; P411-Y517 HydrophobicContact CG-CE1 4.06Å; V420-Y517 HydrophobicContact CB-CE2 4.37Å; V420-Y517 HydrophobicContact CG1-CE2 4.38Å; V420-Y517 HydrophobicContact CG2-CE2 3.92Å; Y422-Y517 WeakPolarHBondContact OH-CE2 3.19Å; I500-Y517 HydrophobicContact CG2-CD1 4.18Å; I500-Y517 HydrophobicContact CG2-CD2 3.73Å; I500-Y517 HydrophobicContact CG2-CE1 3.94Å; I500-Y517 HydrophobicContact CG2-CE2 3.47Å; I500-Y517 VanDerWaalsContact CG2-CE2 3.47Å; I500-Y517 HydrophobicContact CG2-CG 4.07Å; S515-Y517 PolarHBondContact O-N 2.88Å; S515-Y517 VanDerWaalsContact O-N 3.07Å; Y517-R529 WeakPolarHBondContact O-CA 3.4Å; Y517-T530 PolarHBondContact O-N 2.92Å; Y517-T530 PolarHBondContact O-OG1 3.06Å
518C84.3Confident77.6Confident0 Ų032.6 Ų32.60%016%0.164CC..EExtended strand (participates in β ladder)trans-121.2155-169.9-56.20000112.9C503 L506 S515 C527 Y528 T530C503-C518 WeakPolarHBondContact CA-SG 3.25Å; C503-C518 HydrophobicContact CB-CB 3.85Å; C503-C518 WeakPolarHBondContact CB-SG 3.36Å; C503-C518 WeakPolarHBondContact SG-CA 3.46Å; C503-C518 WeakPolarHBondContact SG-CB 3.49Å; C503-C518 CovalentContact SG-SG 2.04Å; C503-C518 PolarHBondContact SG-SG 3.44Å; L506-C518 HydrophobicContact CD1-CB 4.31Å; S515-C518 PolarHBondContact O-N 3.03Å; S515-C518 PolarHBondContact OG-SG 2.88Å; C518-C527 WeakPolarHBondContact CB-SG 3.21Å; C518-Y528 CarbonylContact C-O 3.56Å; C518-Y528 VanDerWaalsContact CA-O 3.25Å; C518-Y528 WeakPolarHBondContact CA-O 3.12Å; C518-T530 WeakPolarHBondContact O-CG2 3.27Å
519A80.4Confident77.7Confident4 Ų434 Ų343%0.03317%0.168CC..EExtended strand (participates in β ladder)trans-140.1137178.500000109.8Y528 T530 A533 I539A519-Y528 PolarHBondContact N-O 2.78Å; A519-Y528 PolarHBondContact O-N 2.9Å; A519-T530 HydrophobicContact CB-CG2 4.1Å; A519-A533 HydrophobicContact CB-CB 4.17Å; A519-I539 HydrophobicContact CB-CG2 3.63Å
520W79.2Confident77.4Confident7 Ų735.6 Ų35.63%0.02718%0.177CC..EExtended strand (participates in β ladder)trans-88.2126.7-178.2-175.2-105000111.8R507 S508 C509 C512 Q525 C527 C551R507-W520 WeakPolarHBondContact O-CH2 3.28Å; S508-W520 VanDerWaalsContact C-CZ3 3.49Å; C509-W520 HydrophobicContact CB-CD2 3.9Å; C509-W520 HydrophobicContact CB-CG 3.93Å; C509-W520 HydrophobicContact CB-CZ2 4.34Å; C512-W520 HydrophobicContact CB-CB 4.32Å; C512-W520 HydrophobicContact CB-CE3 3.75Å; W520-Q525 HydrophobicContact CH2-CB 4.37Å; W520-Q525 VanDerWaalsContact CH2-O 3.28Å; W520-Q525 WeakPolarHBondContact CH2-O 3.33Å; W520-Q525 VanDerWaalsContact CZ2-CA 3.5Å; W520-Q525 HydrophobicContact CZ2-CB 3.96Å; W520-C527 HydrophobicContact CE3-CB 3.94Å; W520-C527 HydrophobicContact CZ3-CB 4.12Å; W520-C551 HydrophobicContact CB-CB 4.38Å; W520-C551 HydrophobicContact CG-CB 4.27Å
521D76Confident76.7Confident0 Ų040.6 Ų40.60%020%0.197CC..EExtended strand (participates in β ladder)trans-89.4106.7166.9-175.4-29.2000109I523 R524 Q525 L526 Y528 I539D521-I523 VanDerWaalsContact C-N 3.28Å; D521-I523 PolarHBondContact O-N 2.82Å; D521-I523 WeakPolarHBondContact OD1-CA 3.3Å; D521-I523 WeakPolarHBondContact OD1-CB 3.47Å; D521-I523 PolarHBondContact OD1-N 3.18Å; D521-R524 HydrophobicContact CB-CB 4.23Å; D521-R524 PolarHBondContact OD1-N 3.26Å; D521-R524 WeakPolarHBondContact OD2-CD 3.22Å; D521-R524 WeakPolarHBondContact OD2-CG 3.04Å; D521-R524 IonicContact OD2-CZ 2.78Å; D521-R524 IonicContact OD2-NE 3.84Å; D521-R524 IonicContact OD2-NH1 2.73Å; D521-R524 PolarHBondContact OD2-NH1 2.7Å; D521-Q525 VanDerWaalsContact O-CA 3.23Å; D521-Q525 WeakPolarHBondContact O-CA 3.06Å; D521-Q525 PolarHBondContact O-N 3.24Å; D521-L526 WeakPolarHBondContact CB-O 3.5Å; D521-L526 PolarHBondContact N-O 3.2Å; D521-L526 PolarHBondContact O-N 3.03Å; D521-Y528 HydrophobicContact CB-CD2 3.84Å; D521-Y528 HydrophobicContact CB-CE2 3.8Å; D521-I539 HydrophobicContact CB-CD1 4.38Å; D521-I539 HydrophobicContact CB-CG1 3.99Å
522S70.5Confident75.5Confident34 Ų3443.1 Ų43.124%0.23821%0.205CC..THydrogen-bonded Turntrans-69.5-22.9-179.862.70000113.6Q525S522-Q525 PolarHBondContact O-NE2 3.07Å
523I68.4Low73.9Confident108 Ų10843.6 Ų43.655%0.55421%0.209SC*.THydrogen-bonded Turntrans-79.1-50.1-179.9-59.5175.4000109D521 R556D521-I523 VanDerWaalsContact C-N 3.28Å; D521-I523 PolarHBondContact O-N 2.82Å; D521-I523 WeakPolarHBondContact OD1-CA 3.3Å; D521-I523 WeakPolarHBondContact OD1-CB 3.47Å; D521-I523 PolarHBondContact OD1-N 3.18Å; I523-R556 PolarHBondContact O-NH1 2.86Å
524R72.1Confident72.4Confident125 Ų12549.9 Ų49.947%0.47224%0.242SC..THydrogen-bonded Turntrans-81.1-16.7-179.6-64.5-173.9177.586.70.7113.8D521 L526 Y528D521-R524 HydrophobicContact CB-CB 4.23Å; D521-R524 PolarHBondContact OD1-N 3.26Å; D521-R524 WeakPolarHBondContact OD2-CD 3.22Å; D521-R524 WeakPolarHBondContact OD2-CG 3.04Å; D521-R524 IonicContact OD2-CZ 2.78Å; D521-R524 IonicContact OD2-NE 3.84Å; D521-R524 IonicContact OD2-NH1 2.73Å; D521-R524 PolarHBondContact OD2-NH1 2.7Å; R524-L526 VanDerWaalsContact C-N 3.27Å; R524-L526 HydrophobicContact CB-CB 4.33Å; R524-L526 HydrophobicContact CB-CD1 4.28Å; R524-L526 HydrophobicContact CB-CG 4.39Å; R524-L526 PolarHBondContact O-N 3.38Å; R524-Y528 WeakPolarHBondContact CD-OH 3.4Å
525Q72.9Confident70.8Confident38 Ų3854.2 Ų54.218%0.17826%0.255CS..THydrogen-bonded Turntrans56.243.9-173.3-61-75.1-54.900111.5W520 D521 S522W520-Q525 HydrophobicContact CH2-CB 4.37Å; W520-Q525 VanDerWaalsContact CH2-O 3.28Å; W520-Q525 WeakPolarHBondContact CH2-O 3.33Å; W520-Q525 VanDerWaalsContact CZ2-CA 3.5Å; W520-Q525 HydrophobicContact CZ2-CB 3.96Å; D521-Q525 VanDerWaalsContact O-CA 3.23Å; D521-Q525 WeakPolarHBondContact O-CA 3.06Å; D521-Q525 PolarHBondContact O-N 3.24Å; S522-Q525 PolarHBondContact O-NE2 3.07Å
526L79Confident68.9Low90 Ų9058.6 Ų58.647%0.47128%0.277SS..EExtended strand (participates in β ladder)trans-132.1145.5-178.2-71.9173.7000110.2D521 R524 Y528D521-L526 WeakPolarHBondContact CB-O 3.5Å; D521-L526 PolarHBondContact N-O 3.2Å; D521-L526 PolarHBondContact O-N 3.03Å; R524-L526 VanDerWaalsContact C-N 3.27Å; R524-L526 HydrophobicContact CB-CB 4.33Å; R524-L526 HydrophobicContact CB-CD1 4.28Å; R524-L526 HydrophobicContact CB-CG 4.39Å; R524-L526 PolarHBondContact O-N 3.38Å; L526-Y528 HydrophobicContact CB-CD2 4.32Å; L526-Y528 HydrophobicContact CB-CE2 3.6Å; L526-Y528 VanDerWaalsContact CD1-OH 3.23Å; L526-Y528 WeakPolarHBondContact CD1-OH 3.32Å
527C80.3Confident67.2Low5 Ų561.2 Ų61.23%0.03431%0.306CS..EExtended strand (participates in β ladder)trans-94.1121.6175.7-171.20000109.6C503 L506 C512 C518 W520C503-C527 HydrophobicContact CB-CB 4.5Å; C503-C527 WeakPolarHBondContact O-CB 3.26Å; L506-C527 HydrophobicContact CB-CB 4.05Å; L506-C527 WeakPolarHBondContact O-CB 3.49Å; C512-C527 VanDerWaalsContact CA-SG 3.58Å; C512-C527 HydrophobicContact CB-CB 3.7Å; C512-C527 WeakPolarHBondContact CB-SG 3.48Å; C512-C527 VanDerWaalsContact SG-CA 3.56Å; C512-C527 WeakPolarHBondContact SG-CB 3.18Å; C512-C527 CovalentContact SG-SG 2.03Å; C512-C527 PolarHBondContact SG-SG 3.01Å; C518-C527 WeakPolarHBondContact CB-SG 3.21Å; W520-C527 HydrophobicContact CE3-CB 3.94Å; W520-C527 HydrophobicContact CZ3-CB 4.12Å
528Y81.5Confident65.4Low68 Ų6861.9 Ų61.927%0.26731%0.314SS..EExtended strand (participates in β ladder)trans-115.9167.3178.7-66.6-75.8000110.4C518 A519 D521 R524 L526 I539C518-Y528 CarbonylContact C-O 3.56Å; C518-Y528 VanDerWaalsContact CA-O 3.25Å; C518-Y528 WeakPolarHBondContact CA-O 3.12Å; A519-Y528 PolarHBondContact N-O 2.78Å; A519-Y528 PolarHBondContact O-N 2.9Å; D521-Y528 HydrophobicContact CB-CD2 3.84Å; D521-Y528 HydrophobicContact CB-CE2 3.8Å; R524-Y528 WeakPolarHBondContact CD-OH 3.4Å; L526-Y528 HydrophobicContact CB-CD2 4.32Å; L526-Y528 HydrophobicContact CB-CE2 3.6Å; L526-Y528 VanDerWaalsContact CD1-OH 3.23Å; L526-Y528 WeakPolarHBondContact CD1-OH 3.32Å; Y528-I539 HydrophobicContact CD2-CD1 4.25Å
529R76.3Confident63.6Low40 Ų4062.5 Ų62.515%0.15132%0.318CS..EExtended strand (participates in β ladder)trans-71142.1171.2-54.2170.7171.6174.9-15.4109.9E484 A501 C503 Y517 K531 H532 A533E484-R529 IonicContact OE1-CZ 3.84Å; E484-R529 IonicContact OE1-NH1 2.86Å; E484-R529 PolarHBondContact OE1-NH1 2.67Å; E484-R529 IonicContact OE1-NH2 3.78Å; A501-R529 HydrophobicContact CB-CG 4.12Å; C503-R529 HydrophobicContact CB-CG 4.44Å; Y517-R529 WeakPolarHBondContact O-CA 3.4Å; R529-K531 PolarHBondContact O-N 3.24Å; R529-K531 VanDerWaalsContact O-N 3.13Å; R529-H532 PolarHBondContact O-N 3.34Å; R529-A533 PolarHBondContact O-N 3.1Å
530T67.8Low62.2Low49 Ų4970.2 Ų70.230%0.30135%0.35SS..Hα-helixtrans-52.4-37-17946.50000113.5Y517 C518 A519 H532 A533Y517-T530 PolarHBondContact O-N 2.92Å; Y517-T530 PolarHBondContact O-OG1 3.06Å; C518-T530 WeakPolarHBondContact O-CG2 3.27Å; A519-T530 HydrophobicContact CB-CG2 4.1Å; T530-H532 VanDerWaalsContact C-N 3.34Å; T530-H532 PolarHBondContact O-N 2.9Å; T530-A533 WeakPolarHBondContact O-CB 3.49Å; T530-A533 PolarHBondContact O-N 3.19Å
531K61.2Low61Low131 Ų13172.4 Ų72.457%0.5736%0.36SS*.Hα-helixtrans-75.7-16180-64.3-174.3179.5-179.70114.9Q483 R529Q483-K531 HydrophobicContact CB-CD 4.22Å; Q483-K531 VanDerWaalsContact CB-NZ 3.25Å; R529-K531 PolarHBondContact O-N 3.24Å; R529-K531 VanDerWaalsContact O-N 3.13Å
532H50.3Low59.9Low82 Ų8273.8 Ų73.838%0.3837%0.369SS..Hα-helixtrans-84-17.9169.6-68.4-63000112.2R529 T530R529-H532 PolarHBondContact O-N 3.34Å; T530-H532 VanDerWaalsContact C-N 3.34Å; T530-H532 PolarHBondContact O-N 2.9Å
533A46.1Very low59.1Low9 Ų972.7 Ų72.77%0.07436%0.362CS..Hα-helixtrans-65.4-38.5-177.500000113.6A519 R529 T530 R535 I539A519-A533 HydrophobicContact CB-CB 4.17Å; R529-A533 PolarHBondContact O-N 3.1Å; T530-A533 WeakPolarHBondContact O-CB 3.49Å; T530-A533 PolarHBondContact O-N 3.19Å; A533-R535 PolarHBondContact O-N 3.34Å; A533-I539 HydrophobicContact CB-CB 3.58Å; A533-I539 HydrophobicContact CB-CD1 4.12Å; A533-I539 HydrophobicContact CB-CG1 4.43Å; A533-I539 HydrophobicContact CB-CG2 3.34Å
534D46.5Very low58.4Low138 Ų13870.4 Ų70.474%0.73835%0.353SS*.THydrogen-bonded Turntrans-68.6-22.7-171.6-149.416.4000113N536D534-N536 PolarHBondContact O-N 3.13Å
535R46.4Very low58Low164 Ų16466.8 Ų66.862%0.61934%0.343SS*.THydrogen-bonded Turntrans-75.4-23.6-172.8-140179.9-169.7-176.14.4114.6A533A533-R535 PolarHBondContact O-N 3.34Å
536N42.8Very low57.4Low105 Ų10565.6 Ų65.656%0.56134%0.339SS*.SBendtrans-113.30.2-174.9-77.7-10000114D534 S538D534-N536 PolarHBondContact O-N 3.13Å; N536-S538 PolarHBondContact O-N 2.88Å
537G44.9Very low56.7Low65 Ų6565.5 Ų65.567%0.6734%0.342SS*.SBendtrans60.7-2.1-179.400000115.6
538S46.2Very low56.1Low38 Ų3872.3 Ų72.327%0.26637%0.373SS..  trans-101.49.2-170.163.30000113.9N536N536-S538 PolarHBondContact O-N 2.88Å
539I46.4Very low55.5Low13 Ų1369.5 Ų69.57%0.06736%0.363CS..  trans-133.9104.6-171.3-59.6166000109.1A519 D521 Y528 A533A519-I539 HydrophobicContact CB-CG2 3.63Å; D521-I539 HydrophobicContact CB-CD1 4.38Å; D521-I539 HydrophobicContact CB-CG1 3.99Å; Y528-I539 HydrophobicContact CD2-CD1 4.25Å; A533-I539 HydrophobicContact CB-CB 3.58Å; A533-I539 HydrophobicContact CB-CD1 4.12Å; A533-I539 HydrophobicContact CB-CG1 4.43Å; A533-I539 HydrophobicContact CB-CG2 3.34Å
540K51.7Low55Low166 Ų16669.6 Ų69.672%0.72237%0.373SS*.  trans-150.968.8174.9-68.2-161.8179.4-168.20113.2
541F53.4Low55.2Low53 Ų5367.5 Ų67.523%0.23236%0.36CS..  trans-138.873.2155.7-54.5-68.8000109A550 C551F541-A550 HydrophobicContact CD1-CB 3.31Å; F541-A550 HydrophobicContact CE1-CB 3.75Å; F541-A550 HydrophobicContact CG-CB 4.23Å; F541-C551 HydrophobicContact CB-CB 3.8Å; F541-C551 HydrophobicContact CD2-CB 3.48Å; F541-C551 VanDerWaalsContact CD2-CB 3.48Å; F541-C551 HydrophobicContact CE2-CB 4.16Å; F541-C551 HydrophobicContact CG-CB 3.75Å
542S53.5Low55.5Low28 Ų2862.9 Ų62.920%0.19634%0.343CS..  trans-81.4112.6148.4-163.80000104.2V413 T544V413-S542 WeakPolarHBondContact CG1-OG 3.44Å; S542-T544 PolarHBondContact O-N 3.03Å
543S52.7Low56.3Low12 Ų1267.6 Ų67.68%0.08437%0.365CS..  trans-75.6125.7-180-163.60000108.2N545 E548S543-N545 WeakPolarHBondContact CB-O 3.18Å; S543-N545 PolarHBondContact O-N 3.01Å; S543-N545 VanDerWaalsContact OG-C 3.27Å; S543-N545 PolarHBondContact OG-N 3.41Å; S543-N545 PolarHBondContact OG-O 2.89Å; S543-E548 PolarHBondContact OG-O 3.05Å
544T55.1Low57.2Low59 Ų5969.6 Ų69.636%0.36238%0.378SS..SBendtrans-61.1-18.7164.9530000111.6D414 S542D414-T544 HydrophobicContact CB-CG2 3.93Å; S542-T544 PolarHBondContact O-N 3.03Å
545N62.5Low58.2Low50 Ų5065 Ų6527%0.26736%0.355SS..SBendtrans-120.5102.4170.5-1720.8000111.9S543 T547 E548S543-N545 WeakPolarHBondContact CB-O 3.18Å; S543-N545 PolarHBondContact O-N 3.01Å; S543-N545 VanDerWaalsContact OG-C 3.27Å; S543-N545 PolarHBondContact OG-N 3.41Å; S543-N545 PolarHBondContact OG-O 2.89Å; N545-T547 VanDerWaalsContact CG-OG1 3.31Å; N545-T547 PolarHBondContact ND2-OG1 3.4Å; N545-T547 VanDerWaalsContact ND2-OG1 3.12Å; N545-T547 PolarHBondContact O-N 2.78Å; N545-T547 VanDerWaalsContact O-N 3.12Å; N545-T547 PolarHBondContact OD1-N 2.77Å; N545-T547 VanDerWaalsContact OD1-N 3.09Å; N545-T547 PolarHBondContact OD1-OG1 2.7Å; N545-E548 CarbonylContact O-C 3.56Å; N545-E548 PolarHBondContact O-N 3Å; N545-E548 VanDerWaalsContact O-N 3.12Å
546P61.8Low59.2Low12 Ų1263.9 Ų63.98%0.07835%0.351CS..THydrogen-bonded Turntrans-56.8-25.3177-27.236.5000114.7F418 Q514 E548F418-P546 HydrophobicContact CE1-CG 4.19Å; Q514-P546 HydrophobicContact CG-CB 4.36Å; P546-E548 VanDerWaalsContact C-N 3.35Å
547T63.9Low61Low89 Ų8967.5 Ų67.555%0.54636%0.357SS..THydrogen-bonded Turntrans-77.1-24.4-17970.70000112.4W436 N545W436-T547 HydrophobicContact CH2-CG2 4.21Å; W436-T547 HydrophobicContact CZ2-CG2 4.15Å; N545-T547 VanDerWaalsContact CG-OG1 3.31Å; N545-T547 PolarHBondContact ND2-OG1 3.4Å; N545-T547 VanDerWaalsContact ND2-OG1 3.12Å; N545-T547 PolarHBondContact O-N 2.78Å; N545-T547 VanDerWaalsContact O-N 3.12Å; N545-T547 PolarHBondContact OD1-N 2.77Å; N545-T547 VanDerWaalsContact OD1-N 3.09Å; N545-T547 PolarHBondContact OD1-OG1 2.7Å
548E66.3Low62.9Low148 Ų14866 Ų6669%0.69233%0.333SS*.SBendtrans-131.874.6178.8-67.1-175.7-179.800110.5S543 N545 P546 A550S543-E548 PolarHBondContact OG-O 3.05Å; N545-E548 CarbonylContact O-C 3.56Å; N545-E548 PolarHBondContact O-N 3Å; N545-E548 VanDerWaalsContact O-N 3.12Å; P546-E548 VanDerWaalsContact C-N 3.35Å; E548-A550 PolarHBondContact O-N 2.96Å
549P68.7Low65Low9 Ų968 Ų686%0.05834%0.344CS..  trans-65.8128.8-179.7-10.221.9000111.4T510 A513 C551 V552T510-P549 HydrophobicContact CG2-CG 4.24Å; A513-P549 HydrophobicContact CB-CB 3.58Å; A513-P549 HydrophobicContact CB-CG 3.88Å; P549-C551 PolarHBondContact O-N 2.91Å; P549-C551 VanDerWaalsContact O-N 3.07Å; P549-V552 HydrophobicContact CB-CG2 4.05Å; P549-V552 HydrophobicContact CG-CG2 3.87Å; P549-V552 VanDerWaalsContact O-CB 3.24Å; P549-V552 WeakPolarHBondContact O-CB 3.29Å; P549-V552 PolarHBondContact O-N 2.86Å
550A67.8Low67.1Low42 Ų4271.9 Ų71.935%0.34736%0.36SS..G310 helixtrans-57.6-25.7175.100000113.3F541 E548 V552 Q553F541-A550 HydrophobicContact CD1-CB 3.31Å; F541-A550 HydrophobicContact CE1-CB 3.75Å; F541-A550 HydrophobicContact CG-CB 4.23Å; E548-A550 PolarHBondContact O-N 2.96Å; A550-V552 PolarHBondContact O-N 2.92Å; A550-Q553 PolarHBondContact O-N 3.38Å
551C71.4Confident68.9Low4 Ų468.5 Ų68.53%0.02735%0.35CS..G310 helixtrans-65.8-20.4173.957.40000114.3C509 W520 F541 P549 Q553 S554C509-C551 HydrophobicContact CB-CB 3.92Å; C509-C551 WeakPolarHBondContact CB-SG 3.31Å; C509-C551 WeakPolarHBondContact SG-CB 3.3Å; C509-C551 CovalentContact SG-SG 2.02Å; C509-C551 PolarHBondContact SG-SG 2.96Å; W520-C551 HydrophobicContact CB-CB 4.38Å; W520-C551 HydrophobicContact CG-CB 4.27Å; F541-C551 HydrophobicContact CB-CB 3.8Å; F541-C551 HydrophobicContact CD2-CB 3.48Å; F541-C551 VanDerWaalsContact CD2-CB 3.48Å; F541-C551 HydrophobicContact CE2-CB 4.16Å; F541-C551 HydrophobicContact CG-CB 3.75Å; P549-C551 PolarHBondContact O-N 2.91Å; P549-C551 VanDerWaalsContact O-N 3.07Å; C551-Q553 VanDerWaalsContact C-N 3.26Å; C551-Q553 PolarHBondContact O-N 3.18Å; C551-S554 WeakPolarHBondContact O-CB 3.47Å; C551-S554 PolarHBondContact O-N 2.74Å
552V67.2Low70.5Confident35 Ų3566.7 Ų66.721%0.21234%0.342CS..G310 helixtrans-65-32.4177.4167.80000111.2C509 T510 P549 A550 S554 V555 T642C509-V552 PolarHBondContact SG-N 3.46Å; T510-V552 HydrophobicContact CG2-CG2 3.58Å; P549-V552 HydrophobicContact CB-CG2 4.05Å; P549-V552 HydrophobicContact CG-CG2 3.87Å; P549-V552 VanDerWaalsContact O-CB 3.24Å; P549-V552 WeakPolarHBondContact O-CB 3.29Å; P549-V552 PolarHBondContact O-N 2.86Å; A550-V552 PolarHBondContact O-N 2.92Å; V552-S554 PolarHBondContact O-N 2.97Å; V552-S554 VanDerWaalsContact O-N 3.17Å; V552-V555 WeakPolarHBondContact O-CG2 3.42Å; V552-T642 HydrophobicContact CB-CG2 4.34Å; V552-T642 HydrophobicContact CG1-CG2 3.15Å; V552-T642 HydrophobicContact CG2-CG2 4.24Å
553Q66.3Low72Confident180 Ų18069.1 Ų69.184%0.84135%0.348SS*.G310 helixtrans-69.1-12.1176.7-62.3-177.5100112.4A550 C551A550-Q553 PolarHBondContact O-N 3.38Å; C551-Q553 VanDerWaalsContact C-N 3.26Å; C551-Q553 PolarHBondContact O-N 3.18Å
554S64.9Low73.4Confident51 Ų5170.6 Ų70.636%0.35736%0.357SS..G310 helixtrans-107.541.2-176.4-58.90000112.5C551 V552 R556C551-S554 WeakPolarHBondContact O-CB 3.47Å; C551-S554 PolarHBondContact O-N 2.74Å; V552-S554 PolarHBondContact O-N 2.97Å; V552-S554 VanDerWaalsContact O-N 3.17Å; S554-R556 PolarHBondContact O-N 3.21Å
555V67.5Low74.6Confident43 Ų4369.2 Ų69.226%0.26135%0.354SS..  trans-63.8106.5175.5-169.20000109.6V552 R557 K643V552-V555 WeakPolarHBondContact O-CG2 3.42Å; V555-R557 PolarHBondContact O-N 2.93Å; V555-K643 HydrophobicContact CG2-CB 4.03Å; V555-K643 WeakPolarHBondContact CG2-O 3.38Å
556R68.7Low75.7Confident139 Ų13969.6 Ų69.653%0.52536%0.356SS..  trans-65.5129176.6-175.8177177.6-175.1-2.3109.5I523 S554 I558I523-R556 PolarHBondContact O-NH1 2.86Å; S554-R556 PolarHBondContact O-N 3.21Å; R556-I558 PolarHBondContact O-N 3.43Å
557R79.5Confident77Confident181 Ų18172.6 Ų72.668%0.68338%0.378SS*.EExtended strand (participates in β ladder)trans-76.5117.3165.6-68.4-172.2-177.2179.82.2109V555 S646V555-R557 PolarHBondContact O-N 2.93Å; R557-S646 CarbonylContact C-O 3.59Å; R557-S646 WeakPolarHBondContact CA-O 3.39Å
558I84.9Confident78.3Confident34 Ų3469.2 Ų69.217%0.17436%0.356CS..EExtended strand (participates in β ladder)trans-95.2105.6177.5-57.9172000107.6R556 K560 V645 S646 Y647 N648R556-I558 PolarHBondContact O-N 3.43Å; I558-K560 HydrophobicContact CG2-CG 4.25Å; I558-V645 HydrophobicContact CD1-CG2 4.04Å; I558-S646 PolarHBondContact N-O 3.44Å; I558-Y647 HydrophobicContact CB-CD1 3.75Å; I558-Y647 HydrophobicContact CB-CE1 3.93Å; I558-Y647 HydrophobicContact CB-CG 4.46Å; I558-Y647 HydrophobicContact CD1-CD1 4.35Å; I558-Y647 HydrophobicContact CD1-CE1 3.73Å; I558-Y647 HydrophobicContact CG1-CE1 4.43Å; I558-Y647 HydrophobicContact CG2-CD1 3.86Å; I558-Y647 HydrophobicContact CG2-CE1 3.83Å; I558-Y647 CarbonylContact O-C 3.59Å; I558-Y647 VanDerWaalsContact O-CA 3.31Å; I558-Y647 WeakPolarHBondContact O-CA 3.33Å; I558-N648 PolarHBondContact O-N 2.88Å
559T91.1Very high79.4Confident80 Ų8065.3 Ų65.349%0.49135%0.345SS..EExtended strand (participates in β ladder)trans-81.1129.6174.3-53.20000109.9N648 L650T559-N648 CarbonylContact C-O 3.54Å; T559-N648 VanDerWaalsContact CA-O 3.31Å; T559-N648 WeakPolarHBondContact CA-O 3.42Å; T559-L650 HydrophobicContact CG2-CD1 3.49Å; T559-L650 VanDerWaalsContact CG2-CD1 3.49Å; T559-L650 HydrophobicContact CG2-CG 3.81Å
560K91.1Very high80.5Confident94 Ų9464.9 Ų64.941%0.40934%0.342SS..EExtended strand (participates in β ladder)trans-123.5125.1174.9-69.1-71.8-172175.90108.5I558 I568 Y647 N648 L649 L650I558-K560 HydrophobicContact CG2-CG 4.25Å; K560-I568 HydrophobicContact CB-CD1 3.9Å; K560-I568 HydrophobicContact CD-CD1 4.22Å; K560-I568 HydrophobicContact CG-CD1 3.73Å; K560-Y647 HydrophobicContact CG-CD1 4.42Å; K560-N648 PolarHBondContact N-O 2.78Å; K560-L649 HydrophobicContact CB-CD2 3.69Å; K560-L649 HydrophobicContact CG-CD2 4.35Å; K560-L650 PolarHBondContact O-N 2.55Å
561L89.1Confident81.2Confident96 Ų9665.3 Ų65.350%0.50334%0.339SS..EExtended strand (participates in β ladder)trans-89127169.4-173.365.1000107.7L650 D652L561-L650 CarbonylContact C-O 3.59Å; L561-L650 WeakPolarHBondContact CA-O 3.39Å; L561-L650 HydrophobicContact CD1-CB 3.9Å; L561-D652 HydrophobicContact CD1-CB 4.02Å
562L87.6Confident81.6Confident14 Ų1465.2 Ų65.27%0.07334%0.338CS..EExtended strand (participates in β ladder)trans-131.2158179.3-61.9172.8000109.7D566 I568 V615 L649 L650 I651 D652L562-D566 HydrophobicContact CB-CB 4.37Å; L562-D566 HydrophobicContact CD2-CB 4.22Å; L562-I568 HydrophobicContact CD1-CB 4.04Å; L562-I568 HydrophobicContact CD1-CD1 4.07Å; L562-I568 HydrophobicContact CD1-CG2 3.8Å; L562-I568 HydrophobicContact CD2-CB 4.26Å; L562-I568 HydrophobicContact CD2-CD1 4.21Å; L562-V615 HydrophobicContact CD1-CG1 4.39Å; L562-V615 HydrophobicContact CD1-CG2 4.24Å; L562-L649 HydrophobicContact CD1-CD1 4.04Å; L562-L649 HydrophobicContact CD1-CD2 4.04Å; L562-L649 HydrophobicContact CD1-CG 4.46Å; L562-L650 PolarHBondContact N-O 2.93Å; L562-I651 HydrophobicContact CB-CD1 3.86Å; L562-I651 HydrophobicContact CD1-CD1 4.44Å; L562-I651 VanDerWaalsContact O-CA 3.31Å; L562-I651 WeakPolarHBondContact O-CA 3.17Å; L562-D652 PolarHBondContact O-N 3.44Å
563Y83.6Confident81.7Confident80 Ų8067 Ų6731%0.31434%0.341SS..  trans-109.4154.5173.8-57.1-81.8000110.3G565 D566 D652Y563-G565 PolarHBondContact O-N 2.91Å; Y563-D566 PolarHBondContact N-OD2 2.89Å; Y563-D566 VanDerWaalsContact O-CB 3.27Å; Y563-D566 WeakPolarHBondContact O-CB 3.29Å; Y563-D566 PolarHBondContact O-N 3.29Å; Y563-D652 HydrophobicContact CD1-CB 4.08Å; Y563-D652 WeakPolarHBondContact CD1-O 3.22Å; Y563-D652 HydrophobicContact CE1-CB 3.88Å
564P83.3Confident81.4Confident43 Ų4359.9 Ų59.928%0.27931%0.308SS..THydrogen-bonded Turntrans-54.5128.3173.1-25.734.8000111.9V615 C616 I651 D652 D653P564-V615 CarbonylContact C-O 3.5Å; P564-V615 VanDerWaalsContact CA-O 3.29Å; P564-V615 WeakPolarHBondContact CA-O 3.45Å; P564-C616 HydrophobicContact CB-CB 4.4Å; P564-I651 HydrophobicContact CG-CG2 4.19Å; P564-D652 WeakPolarHBondContact CD-O 3.35Å; P564-D653 HydrophobicContact CG-CB 4.28Å
565G79.6Confident80.6Confident29 Ų2968.2 Ų68.230%0.29933%0.332SS..THydrogen-bonded Turntrans96.8-15.2-174.800000114.9Y563 V615 T617Y563-G565 PolarHBondContact O-N 2.91Å; G565-V615 PolarHBondContact N-O 2.82Å; G565-T617 VanDerWaalsContact CA-CG2 3.46Å
566D86Confident79.4Confident58 Ų5875.3 Ų75.331%0.3135%0.354SS..  trans-62160.2177.7-76.4-9.5000112L562 Y563 N614 V615L562-D566 HydrophobicContact CB-CB 4.37Å; L562-D566 HydrophobicContact CD2-CB 4.22Å; Y563-D566 PolarHBondContact N-OD2 2.89Å; Y563-D566 VanDerWaalsContact O-CB 3.27Å; Y563-D566 WeakPolarHBondContact O-CB 3.29Å; Y563-D566 PolarHBondContact O-N 3.29Å; D566-N614 PolarHBondContact O-N 2.99Å; D566-V615 WeakPolarHBondContact O-CB 3.47Å; D566-V615 VanDerWaalsContact O-CG2 3.23Å; D566-V615 WeakPolarHBondContact O-CG2 3.11Å; D566-V615 PolarHBondContact O-N 2.8Å
567S88.1Confident78.3Confident76 Ų7674.1 Ų74.153%0.53135%0.354SS..  trans-123.3136.5169.6-58.90000109.7I612 I613S567-I612 CarbonylContact C-O 3.5Å; S567-I612 WeakPolarHBondContact CA-O 3.24Å; S567-I613 WeakPolarHBondContact OG-CA 3.39Å
568I91.2Very high76.4Confident17 Ų1771.3 Ų71.39%0.08736%0.362CS..EExtended strand (participates in β ladder)trans-129.6143-179.5-170.7171.2000110.8K560 L562 M570 I611 I612 V615 L649K560-I568 HydrophobicContact CB-CD1 3.9Å; K560-I568 HydrophobicContact CD-CD1 4.22Å; K560-I568 HydrophobicContact CG-CD1 3.73Å; L562-I568 HydrophobicContact CD1-CB 4.04Å; L562-I568 HydrophobicContact CD1-CD1 4.07Å; L562-I568 HydrophobicContact CD1-CG2 3.8Å; L562-I568 HydrophobicContact CD2-CB 4.26Å; L562-I568 HydrophobicContact CD2-CD1 4.21Å; I568-M570 HydrophobicContact CD1-CG 4.03Å; I568-M570 HydrophobicContact CD1-SD 4.5Å; I568-M570 HydrophobicContact CG1-CG 4.1Å; I568-I611 CarbonylContact O-C 3.55Å; I568-I611 WeakPolarHBondContact O-CA 3.35Å; I568-I612 HydrophobicContact CG2-CB 4.02Å; I568-I612 HydrophobicContact CG2-CD1 4.41Å; I568-I612 HydrophobicContact CG2-CG1 4.3Å; I568-I612 PolarHBondContact N-O 2.71Å; I568-I612 PolarHBondContact O-N 2.97Å; I568-V615 HydrophobicContact CG2-CG2 4.49Å; I568-L649 HydrophobicContact CD1-CD2 4Å; I568-L649 HydrophobicContact CG2-CD1 4.42Å
569S90.7Very high74.4Confident66 Ų6672.6 Ų72.646%0.46238%0.384SS..EExtended strand (participates in β ladder)trans-112125.5166.6-179.20000109.8
570M90.8Very high72Confident0 Ų072.5 Ų72.50%038%0.38CS..EExtended strand (participates in β ladder)trans-117.1115.7-178.4-66.8-175.9-66.900108.8I568 W588 S609 L610 I612 Y635 Y647 L649I568-M570 HydrophobicContact CD1-CG 4.03Å; I568-M570 HydrophobicContact CD1-SD 4.5Å; I568-M570 HydrophobicContact CG1-CG 4.1Å; M570-W588 HydrophobicContact CB-CH2 3.88Å; M570-W588 HydrophobicContact CB-CZ3 4.47Å; M570-W588 VanDerWaalsContact O-CZ2 3.31Å; M570-W588 WeakPolarHBondContact O-CZ2 3.47Å; M570-S609 CarbonylContact O-C 3.58Å; M570-S609 WeakPolarHBondContact O-CA 3.26Å; M570-S609 VanDerWaalsContact O-CB 3.32Å; M570-S609 WeakPolarHBondContact O-CB 3.46Å; M570-L610 HydrophobicContact CE-CB 4.23Å; M570-L610 HydrophobicContact CE-CD2 3.65Å; M570-L610 HydrophobicContact CE-CG 3.94Å; M570-L610 PolarHBondContact N-O 2.87Å; M570-L610 PolarHBondContact O-N 3.14Å; M570-I612 HydrophobicContact CE-CD1 3.59Å; M570-I612 HydrophobicContact CE-CG1 4.08Å; M570-Y635 HydrophobicContact CE-CD1 4.14Å; M570-Y635 HydrophobicContact CE-CD2 4.31Å; M570-Y635 HydrophobicContact CE-CG 3.88Å; M570-Y647 HydrophobicContact CB-CD1 4.32Å; M570-Y647 HydrophobicContact CB-CD2 3.82Å; M570-Y647 HydrophobicContact CB-CE1 4.16Å; M570-Y647 HydrophobicContact CB-CE2 3.62Å; M570-Y647 HydrophobicContact CB-CG 4.16Å; M570-Y647 HydrophobicContact CG-CD1 3.81Å; M570-Y647 HydrophobicContact CG-CD2 4.05Å; M570-Y647 HydrophobicContact CG-CE1 3.95Å; M570-Y647 HydrophobicContact CG-CE2 4.18Å; M570-Y647 HydrophobicContact CG-CG 3.86Å; M570-Y647 WeakPolarHBondContact SD-CB 3.27Å; M570-Y647 HydrophobicContact SD-CD1 3.84Å; M570-Y647 HydrophobicContact SD-CD2 3.88Å; M570-Y647 HydrophobicContact SD-CG 3.45Å; M570-L649 HydrophobicContact CE-CD1 4.26Å; M570-L649 HydrophobicContact SD-CD1 4.25Å; M570-L649 HydrophobicContact SD-CD2 3.91Å; M570-L649 HydrophobicContact SD-CG 4.33Å
571N83.7Confident69.6Low52 Ų5277.7 Ų77.728%0.27841%0.406SS..  trans-84.8129.7-174-66.1-36.3000110.7Y573 S609 Y647N571-Y573 VanDerWaalsContact C-N 3.27Å; N571-Y573 HydrophobicContact CB-CD1 3.87Å; N571-Y573 HydrophobicContact CB-CD2 4.32Å; N571-Y573 HydrophobicContact CB-CE1 3.68Å; N571-Y573 HydrophobicContact CB-CE2 4.12Å; N571-Y573 HydrophobicContact CB-CG 4.22Å; N571-Y573 WeakPolarHBondContact O-CD2 3.45Å; N571-S609 WeakPolarHBondContact OD1-CB 3.06Å; N571-S609 PolarHBondContact OD1-OG 3.35Å; N571-Y647 PolarHBondContact N-OH 3.04Å; N571-Y647 PolarHBondContact O-OH 2.76Å
572C79.4Confident67.3Low1 Ų180.9 Ų80.91%0.00742%0.423CS..  trans-82.7-7.1169.5-173.50000112.8Q574 W588 N608 C637C572-Q574 PolarHBondContact O-N 3.07Å; C572-Q574 VanDerWaalsContact O-N 3.07Å; C572-W588 HydrophobicContact CB-CZ2 3.62Å; C572-N608 HydrophobicContact CB-CB 4.26Å; C572-N608 WeakPolarHBondContact CB-O 3.16Å; C572-C637 HydrophobicContact CB-CB 3.77Å; C572-C637 WeakPolarHBondContact CB-SG 3.41Å; C572-C637 WeakPolarHBondContact SG-CB 3.37Å; C572-C637 CovalentContact SG-SG 2.01Å; C572-C637 PolarHBondContact SG-SG 3.18Å
573Y67.9Low65.5Low72 Ų7285.4 Ų85.428%0.28244%0.442SS..  trans5325.9178.6-55.7-69.6000115.6R507 S508 N571R507-Y573 HydrophobicContact CB-CD1 3.95Å; R507-Y573 HydrophobicContact CB-CG 4.46Å; R507-Y573 VanDerWaalsContact O-CB 3.26Å; R507-Y573 WeakPolarHBondContact O-CB 3.5Å; S508-Y573 WeakPolarHBondContact CB-O 3.36Å; N571-Y573 VanDerWaalsContact C-N 3.27Å; N571-Y573 HydrophobicContact CB-CD1 3.87Å; N571-Y573 HydrophobicContact CB-CD2 4.32Å; N571-Y573 HydrophobicContact CB-CE1 3.68Å; N571-Y573 HydrophobicContact CB-CE2 4.12Å; N571-Y573 HydrophobicContact CB-CG 4.22Å; N571-Y573 WeakPolarHBondContact O-CD2 3.45Å
574Q60.4Low64.3Low31 Ų3185.1 Ų85.115%0.14546%0.456CS..  trans-125126173.3-93.1-160.6-16.700112.4C572 P586 N608 Q639 L644C572-Q574 PolarHBondContact O-N 3.07Å; C572-Q574 VanDerWaalsContact O-N 3.07Å; Q574-P586 HydrophobicContact CB-CG 4.29Å; Q574-N608 PolarHBondContact O-ND2 3.32Å; Q574-Q639 VanDerWaalsContact CD-OE1 3.27Å; Q574-L644 HydrophobicContact CG-CD1 3.99Å
575R47.6Very low63.7Low226 Ų22684.8 Ų84.885%0.85346%0.461SS*.  trans-78.7137.1170.1-165.3173.3-176.4167.30.9109.5E577R575-E577 PolarHBondContact O-N 2.95Å
576R43.8Very low63.7Low193 Ų19384.1 Ų84.173%0.72845%0.451SS*.  trans-60.9121171.7-166.6175.4-175.9178.91.5108.9S578R576-S578 PolarHBondContact O-N 2.99Å
577E45.3Very low63.9Low114 Ų11485 Ų8553%0.53346%0.458SS..  trans-63.2102.5172.3-72.4179.2-176.100108.2R575 G579 K583R575-E577 PolarHBondContact O-N 2.95Å; E577-G579 PolarHBondContact O-N 3.43Å; E577-G579 VanDerWaalsContact O-N 3.09Å; E577-K583 IonicContact OE2-NZ 2.68Å
578S39.7Very low64.1Low121 Ų12181.5 Ų81.585%0.84643%0.434SS*.THydrogen-bonded Turntrans-71.7100.3173.142.10000108.8R576R576-S578 PolarHBondContact O-N 2.99Å
579G43.3Very low64.2Low62 Ų6282.6 Ų82.664%0.63944%0.439SS*.THydrogen-bonded Turntrans142.6-17.4167.800000116.3E577E577-G579 PolarHBondContact O-N 3.43Å; E577-G579 VanDerWaalsContact O-N 3.09Å
580D39.9Very low64.2Low77 Ų7781.4 Ų81.441%0.41243%0.426SS..  trans-105.898176.1-119.40.4000109.6L582D580-L582 PolarHBondContact O-N 2.81Å; D580-L582 VanDerWaalsContact O-N 3.12Å
581Q40.1Very low64.2Low204 Ų20485.2 Ų85.295%0.95345%0.447SS*.THydrogen-bonded Turntrans-64-11.5175.5-67.5-176.3-4.800112.7
582L41.8Very low64.4Low163 Ų16388.7 Ų88.785%0.85347%0.465SS*.THydrogen-bonded Turntrans-90.7-24-176-89.8100.8000115.6D580 A584D580-L582 PolarHBondContact O-N 2.81Å; D580-L582 VanDerWaalsContact O-N 3.12Å; L582-A584 PolarHBondContact O-N 2.85Å
583K49.1Very low64.9Low108 Ų10898.1 Ų98.147%0.4750%0.5SS..SBendtrans-91108.6179.6-76.1-176.6-172.7167.60110.2E577 G585E577-K583 IonicContact OE2-NZ 2.68Å; K583-G585 PolarHBondContact O-N 2.84Å
584A59.2Low66Low74 Ų7499 Ų9961%0.61252%0.517SS*.PPolyproline II helixtrans-54.8128.3171.400000109.9L582L582-A584 PolarHBondContact O-N 2.85Å
585G69.2Low67.4Low37 Ų3798.1 Ų98.138%0.38151%0.514SS..PPolyproline II helixtrans-61.7170.3174.200000111.9K583K583-G585 PolarHBondContact O-N 2.84Å
586P81.5Confident69.1Low14 Ų1491.9 Ų91.99%0.09150%0.497CS..PPolyproline II helixtrans-63.2146.1176.330.2-36.6000111.1Q574 N608 V638 Q639 L644Q574-P586 HydrophobicContact CB-CG 4.29Å; P586-N608 HydrophobicContact CG-CB 3.91Å; P586-V638 WeakPolarHBondContact CA-O 3.33Å; P586-Q639 HydrophobicContact CB-CB 4.22Å; P586-Q639 HydrophobicContact CB-CG 4.46Å; P586-L644 HydrophobicContact CB-CD1 3.94Å
587V89.3Confident71.2Confident76 Ų7686.2 Ų86.246%0.46148%0.478SS..EExtended strand (participates in β ladder)trans-115.6138.3-178.7-1790000109.3L589 V638V587-L589 HydrophobicContact CG1-CD2 4.3Å; V587-V638 PolarHBondContact N-O 3.23Å; V587-V638 PolarHBondContact O-N 3.47Å
588W92.4Very high72.8Confident3 Ų389.1 Ų89.11%0.01149%0.491CS..EExtended strand (participates in β ladder)trans-90.4131.7173.8-76.595.3000111.4M570 C572 V595 F597 N608 L610 E636 C637 V645 Y647M570-W588 HydrophobicContact CB-CH2 3.88Å; M570-W588 HydrophobicContact CB-CZ3 4.47Å; M570-W588 VanDerWaalsContact O-CZ2 3.31Å; M570-W588 WeakPolarHBondContact O-CZ2 3.47Å; C572-W588 HydrophobicContact CB-CZ2 3.62Å; W588-V595 HydrophobicContact CB-CB 4.26Å; W588-V595 HydrophobicContact CB-CG2 3.85Å; W588-V595 PolarHBondContact O-N 2.91Å; W588-F597 HydrophobicContact CB-CZ 4.41Å; W588-N608 PolarHBondContact NE1-O 3.24Å; W588-L610 HydrophobicContact CB-CD2 4.32Å; W588-L610 HydrophobicContact CD2-CB 3.65Å; W588-L610 HydrophobicContact CD2-CD2 3.95Å; W588-L610 HydrophobicContact CD2-CG 4.41Å; W588-L610 VanDerWaalsContact CE2-CB 3.48Å; W588-L610 HydrophobicContact CE3-CB 4.08Å; W588-L610 HydrophobicContact CE3-CD2 3.86Å; W588-L610 HydrophobicContact CG-CB 4.06Å; W588-L610 HydrophobicContact CG-CD2 4.18Å; W588-L610 HydrophobicContact CH2-CB 4.16Å; W588-L610 HydrophobicContact CZ2-CB 3.74Å; W588-L610 HydrophobicContact CZ3-CB 4.32Å; W588-L610 HydrophobicContact CZ3-CD2 4.44Å; W588-E636 CarbonylContact C-O 3.58Å; W588-E636 WeakPolarHBondContact CA-O 3.24Å; W588-C637 HydrophobicContact CD2-CB 3.96Å; W588-C637 HydrophobicContact CE3-CB 3.99Å; W588-C637 HydrophobicContact CH2-CB 3.96Å; W588-C637 HydrophobicContact CZ2-CB 3.92Å; W588-C637 HydrophobicContact CZ3-CB 3.99Å; W588-V645 HydrophobicContact CH2-CG1 3.9Å; W588-V645 HydrophobicContact CZ3-CG1 4.36Å; W588-Y647 HydrophobicContact CH2-CD2 4Å; W588-Y647 AromaticContact CH2-CE2 3.95Å; W588-Y647 HydrophobicContact CH2-CE2 3.95Å; W588-Y647 HydrophobicContact CZ3-CD2 4.08Å; W588-Y647 HydrophobicContact CZ3-CE2 4.48Å
589L92.4Very high74.6Confident40 Ų4085.9 Ų85.921%0.20947%0.465CS..EExtended strand (participates in β ladder)trans-116.3130.7175.7-54.5179.5000109.6V587 R593 Y635 E636 V638V587-L589 HydrophobicContact CG1-CD2 4.3Å; L589-R593 CarbonylContact C-O 3.37Å; L589-R593 WeakPolarHBondContact CA-O 3.23Å; L589-Y635 CarbonylContact O-C 3.53Å; L589-Y635 VanDerWaalsContact O-CA 3.26Å; L589-Y635 WeakPolarHBondContact O-CA 3.24Å; L589-E636 PolarHBondContact N-O 3.2Å; L589-E636 PolarHBondContact O-N 2.99Å; L589-V638 HydrophobicContact CD1-CB 4.43Å; L589-V638 HydrophobicContact CD1-CG2 3.77Å; L589-V638 HydrophobicContact CG-CG2 4.3Å
590F91.8Very high76.3Confident42 Ų4285.2 Ų85.218%0.18446%0.458CS..EExtended strand (participates in β ladder)trans-104.4120165.4174-118.3000109.3N592 R593 V595 E630 S634 Y635F590-N592 PolarHBondContact O-N 3.11Å; F590-R593 PolarHBondContact N-O 2.96Å; F590-R593 PolarHBondContact O-N 3.17Å; F590-V595 HydrophobicContact CB-CG2 3.95Å; F590-E630 WeakPolarHBondContact CE1-O 3.32Å; F590-E630 WeakPolarHBondContact CZ-O 3.47Å; F590-S634 CarbonylContact C-O 3.58Å; F590-S634 WeakPolarHBondContact CA-O 2.99Å; F590-Y635 HydrophobicContact CB-CD1 3.99Å; F590-Y635 HydrophobicContact CB-CE1 3.77Å; F590-Y635 AromaticContact CD2-CD1 3.98Å; F590-Y635 HydrophobicContact CD2-CD1 3.98Å; F590-Y635 AromaticContact CD2-CD2 3.76Å; F590-Y635 HydrophobicContact CD2-CD2 3.76Å; F590-Y635 AromaticContact CD2-CE1 3.57Å; F590-Y635 HydrophobicContact CD2-CE1 3.57Å; F590-Y635 AromaticContact CD2-CE2 3.3Å; F590-Y635 HydrophobicContact CD2-CE2 3.3Å; F590-Y635 HydrophobicContact CD2-CG 4.08Å; F590-Y635 AromaticContact CD2-CZ 3.21Å; F590-Y635 HydrophobicContact CE2-CD2 4.2Å; F590-Y635 HydrophobicContact CE2-CE1 4.4Å; F590-Y635 AromaticContact CE2-CE2 3.47Å; F590-Y635 HydrophobicContact CE2-CE2 3.47Å; F590-Y635 VanDerWaalsContact CE2-CE2 3.47Å; F590-Y635 AromaticContact CE2-CZ 3.6Å; F590-Y635 HydrophobicContact CG-CD1 4.38Å; F590-Y635 AromaticContact CG-CE1 3.88Å; F590-Y635 HydrophobicContact CG-CE1 3.88Å; F590-Y635 HydrophobicContact CG-CE2 4.36Å; F590-Y635 AromaticContact CG-CZ 3.86Å
591N90.3Very high78.4Confident80 Ų8085 Ų8543%0.42845%0.451SS..THydrogen-bonded Turntrans47.545.4-176.8-66.6-27.2000112.7R593 S634N591-R593 VanDerWaalsContact C-N 3.27Å; N591-R593 PolarHBondContact O-N 3.15Å; N591-S634 PolarHBondContact N-O 2.98Å; N591-S634 PolarHBondContact OD1-N 3.4Å
592N88.2Confident80.8Confident124 Ų12476.3 Ų76.366%0.66341%0.411SS*.THydrogen-bonded Turntrans65.713.7-176-60.7-23.6000116.4F590F590-N592 PolarHBondContact O-N 3.11Å
593R91Very high83.1Confident200 Ų20073 Ų7376%0.75539%0.389SS*.EExtended strand (participates in β ladder)trans-113.2144.9172.5-61.3-175.5179.9-146.7-0.3110L589 F590 N591 V595L589-R593 CarbonylContact C-O 3.37Å; L589-R593 WeakPolarHBondContact CA-O 3.23Å; F590-R593 PolarHBondContact N-O 2.96Å; F590-R593 PolarHBondContact O-N 3.17Å; N591-R593 VanDerWaalsContact C-N 3.27Å; N591-R593 PolarHBondContact O-N 3.15Å; R593-V595 PolarHBondContact O-N 3.23Å
594S89.4Confident85Confident90 Ų9071.7 Ų71.763%0.62939%0.388SS*.EExtended strand (participates in β ladder)trans-56.6133.3175.652.30000110.8D596S594-D596 PolarHBondContact O-N 2.94Å
595V89.8Confident86.1Confident12 Ų1269.6 Ų69.67%0.07337%0.368CS..PPolyproline II helixtrans-63.4131.2172.61760000109.1W588 F590 R593 F597 H602 L610 Y635W588-V595 HydrophobicContact CB-CB 4.26Å; W588-V595 HydrophobicContact CB-CG2 3.85Å; W588-V595 PolarHBondContact O-N 2.91Å; F590-V595 HydrophobicContact CB-CG2 3.95Å; R593-V595 PolarHBondContact O-N 3.23Å; V595-F597 HydrophobicContact CB-CE2 4.26Å; V595-F597 HydrophobicContact CB-CZ 4.25Å; V595-F597 HydrophobicContact CG1-CE1 4.23Å; V595-F597 HydrophobicContact CG1-CE2 4.38Å; V595-F597 HydrophobicContact CG1-CZ 4.15Å; V595-F597 WeakPolarHBondContact O-CD2 3.39Å; V595-H602 HydrophobicContact CG1-CB 3.67Å; V595-H602 VanDerWaalsContact CG1-CG 3.49Å; V595-L610 HydrophobicContact CG1-CD1 4.24Å; V595-L610 HydrophobicContact CG2-CD2 4.2Å; V595-Y635 HydrophobicContact CG2-CD1 4.18Å; V595-Y635 HydrophobicContact CG2-CE1 4.31Å
596D84.4Confident86.3Confident95 Ų9574.6 Ų74.651%0.50839%0.391SS..PPolyproline II helixtrans-85.1117.5172.5-176.410.7000109.7S594 Q598S594-D596 PolarHBondContact O-N 2.94Å; D596-Q598 VanDerWaalsContact C-N 3.35Å; D596-Q598 WeakPolarHBondContact OD1-CB 3.29Å; D596-Q598 PolarHBondContact OD1-N 3.04Å
597F86.3Confident85.8Confident75 Ų7578.4 Ų78.433%0.32941%0.408SS..THydrogen-bonded Turntrans-90.92.5178.9-65.2-81000113.1W588 V595 H602 L604 L610W588-F597 HydrophobicContact CB-CZ 4.41Å; V595-F597 HydrophobicContact CB-CE2 4.26Å; V595-F597 HydrophobicContact CB-CZ 4.25Å; V595-F597 HydrophobicContact CG1-CE1 4.23Å; V595-F597 HydrophobicContact CG1-CE2 4.38Å; V595-F597 HydrophobicContact CG1-CZ 4.15Å; V595-F597 WeakPolarHBondContact O-CD2 3.39Å; F597-H602 HydrophobicContact CD1-CB 4.08Å; F597-H602 HydrophobicContact CE1-CB 4.43Å; F597-L604 HydrophobicContact CD1-CB 4.23Å; F597-L604 HydrophobicContact CE1-CB 3.77Å; F597-L604 HydrophobicContact CE1-CD1 4.25Å; F597-L604 HydrophobicContact CZ-CB 4.25Å; F597-L604 HydrophobicContact CZ-CD1 4.13Å; F597-L610 HydrophobicContact CE1-CD1 3.63Å; F597-L610 HydrophobicContact CZ-CD1 4.19Å
598Q79.8Confident85.5Confident174 Ų17475.4 Ų75.481%0.81339%0.389SS*.THydrogen-bonded Turntrans-93.3-1.9175.7-59.8-62.1-33.300112.9D596 G600D596-Q598 VanDerWaalsContact C-N 3.35Å; D596-Q598 WeakPolarHBondContact OD1-CB 3.29Å; D596-Q598 PolarHBondContact OD1-N 3.04Å; Q598-G600 VanDerWaalsContact C-N 3.25Å; Q598-G600 PolarHBondContact O-N 3.37Å
599D78.2Confident85.2Confident54 Ų5475.4 Ų75.429%0.28939%0.39SS..SBendtrans-79.1-3.9-174.878.6-16.2000114.6R601 H602D599-R601 PolarHBondContact O-N 2.98Å; D599-R601 PolarHBondContact OD1-N 3.11Å; D599-R601 IonicContact OD2-NE 3.34Å; D599-H602 VanDerWaalsContact CG-ND1 3.33Å; D599-H602 IonicContact OD1-CG 3.9Å; D599-H602 PolarHBondContact OD1-N 3.39Å; D599-H602 IonicContact OD1-ND1 3.2Å; D599-H602 PolarHBondContact OD1-ND1 2.95Å; D599-H602 IonicContact OD2-CE1 2.72Å; D599-H602 PolarHBondContact OD2-CE1 2.92Å; D599-H602 VanDerWaalsContact OD2-CE1 3.29Å; D599-H602 IonicContact OD2-CG 2.74Å; D599-H602 IonicContact OD2-ND1 3.02Å; D599-H602 PolarHBondContact OD2-ND1 3.43Å
600G79.3Confident85.2Confident48 Ų4873.5 Ų73.550%0.49538%0.38SS..SBendtrans72.12.5-178.300000115.2Q598 F603Q598-G600 VanDerWaalsContact C-N 3.25Å; Q598-G600 PolarHBondContact O-N 3.37Å; G600-F603 WeakPolarHBondContact O-CE2 3.41Å; G600-F603 WeakPolarHBondContact O-CZ 3.32Å
601R83.7Confident85.2Confident71 Ų7174.1 Ų74.127%0.26838%0.384SS..SBendtrans-111.4-35.2179.9-70.4-178-89.8-175.9-4.3112.2D599 F603 I612 I613D599-R601 PolarHBondContact O-N 2.98Å; D599-R601 PolarHBondContact OD1-N 3.11Å; D599-R601 IonicContact OD2-NE 3.34Å; R601-F603 WeakPolarHBondContact O-CD2 3.29Å; R601-I612 WeakPolarHBondContact O-CA 3.49Å; R601-I613 PolarHBondContact O-N 3.36Å
602H89.9Confident85.2Confident22 Ų2270.5 Ų70.510%0.10237%0.365CS..EExtended strand (participates in β ladder)trans-96.7128.6179.2-62.389.5000111.4V595 F597 D599 L610 Y635V595-H602 HydrophobicContact CG1-CB 3.67Å; V595-H602 VanDerWaalsContact CG1-CG 3.49Å; F597-H602 HydrophobicContact CD1-CB 4.08Å; F597-H602 HydrophobicContact CE1-CB 4.43Å; D599-H602 VanDerWaalsContact CG-ND1 3.33Å; D599-H602 IonicContact OD1-CG 3.9Å; D599-H602 PolarHBondContact OD1-N 3.39Å; D599-H602 IonicContact OD1-ND1 3.2Å; D599-H602 PolarHBondContact OD1-ND1 2.95Å; D599-H602 IonicContact OD2-CE1 2.72Å; D599-H602 PolarHBondContact OD2-CE1 2.92Å; D599-H602 VanDerWaalsContact OD2-CE1 3.29Å; D599-H602 IonicContact OD2-CG 2.74Å; D599-H602 IonicContact OD2-ND1 3.02Å; D599-H602 PolarHBondContact OD2-ND1 3.43Å; H602-L610 HydrophobicContact CB-CD1 4.15Å; H602-Y635 AromaticContact NE2-CE1 3.61Å; H602-Y635 AromaticContact NE2-CZ 3.95Å; H602-Y635 PolarHBondContact NE2-OH 2.95Å
603F90.5Very high85.2Confident93 Ų9367.3 Ų67.341%0.40835%0.347SS..EExtended strand (participates in β ladder)trans-128.5142178.4-61.1-94.7000109.7G600 R601 I611 I613G600-F603 WeakPolarHBondContact O-CE2 3.41Å; G600-F603 WeakPolarHBondContact O-CZ 3.32Å; R601-F603 WeakPolarHBondContact O-CD2 3.29Å; F603-I611 HydrophobicContact CB-CB 4.2Å; F603-I611 PolarHBondContact N-O 3.37Å; F603-I611 PolarHBondContact O-N 3.3Å; F603-I613 HydrophobicContact CD2-CD1 4.14Å; F603-I613 HydrophobicContact CD2-CG1 4.16Å; F603-I613 HydrophobicContact CE2-CD1 3.29Å; F603-I613 HydrophobicContact CE2-CG1 3.58Å; F603-I613 HydrophobicContact CZ-CD1 3.83Å
604L88.1Confident84.7Confident82 Ų8261.8 Ų61.843%0.42933%0.332SS..EExtended strand (participates in β ladder)trans-104.1125.4174.5-165.968.9000109.7F597F597-L604 HydrophobicContact CD1-CB 4.23Å; F597-L604 HydrophobicContact CE1-CB 3.77Å; F597-L604 HydrophobicContact CE1-CD1 4.25Å; F597-L604 HydrophobicContact CZ-CB 4.25Å; F597-L604 HydrophobicContact CZ-CD1 4.13Å
605S82.6Confident84.5Confident30 Ų3057.6 Ų57.621%0.2130%0.303CS..  trans-74.9164.917488.40000111.6E607 N608 S609S605-E607 PolarHBondContact O-N 2.87Å; S605-E607 VanDerWaalsContact O-N 3.17Å; S605-E607 PolarHBondContact OG-N 2.88Å; S605-E607 VanDerWaalsContact OG-N 3.09Å; S605-N608 PolarHBondContact O-N 3.23Å; S605-S609 PolarHBondContact N-O 3.28Å; S605-S609 VanDerWaalsContact OG-CB 3.26Å; S605-S609 WeakPolarHBondContact OG-CB 3.37Å; S605-S609 PolarHBondContact OG-N 2.56Å; S605-S609 PolarHBondContact OG-OG 2.74Å
606V73.2Confident83.9Confident141 Ų14157.2 Ų57.286%0.85530%0.301SS*.THydrogen-bonded Turntrans-60.4-20.8171.3-66.30000113.6N608V606-N608 VanDerWaalsContact C-N 3.35Å
607E71.1Confident83.2Confident94 Ų9454.8 Ų54.844%0.43929%0.29SS..THydrogen-bonded Turntrans-9414.2175.5-59.2-168.1168.200112.7R507 S605 S609R507-E607 IonicContact NH1-OE1 2.81Å; R507-E607 IonicContact NH1-OE2 3.88Å; R507-E607 PolarHBondContact NH1-OE2 2.75Å; R507-E607 VanDerWaalsContact NH1-OE2 3.08Å; S605-E607 PolarHBondContact O-N 2.87Å; S605-E607 VanDerWaalsContact O-N 3.17Å; S605-E607 PolarHBondContact OG-N 2.88Å; S605-E607 VanDerWaalsContact OG-N 3.09Å; E607-S609 PolarHBondContact O-N 2.84Å
608N82.2Confident82Confident14 Ų1454.2 Ų54.28%0.07529%0.292CS..SBendtrans59.723.4-173.1-57.8-49.8000114.3C572 Q574 P586 W588 S605 V606C572-N608 HydrophobicContact CB-CB 4.26Å; C572-N608 WeakPolarHBondContact CB-O 3.16Å; Q574-N608 PolarHBondContact O-ND2 3.32Å; P586-N608 HydrophobicContact CG-CB 3.91Å; W588-N608 PolarHBondContact NE1-O 3.24Å; S605-N608 PolarHBondContact O-N 3.23Å; V606-N608 VanDerWaalsContact C-N 3.35Å
609S86.7Confident80.8Confident3 Ų353.9 Ų53.92%0.02129%0.29CS..  trans-76.3135.1171.1-49.50000109.8M570 N571 S605 E607M570-S609 CarbonylContact O-C 3.58Å; M570-S609 WeakPolarHBondContact O-CA 3.26Å; M570-S609 VanDerWaalsContact O-CB 3.32Å; M570-S609 WeakPolarHBondContact O-CB 3.46Å; N571-S609 WeakPolarHBondContact OD1-CB 3.06Å; N571-S609 PolarHBondContact OD1-OG 3.35Å; S605-S609 PolarHBondContact N-O 3.28Å; S605-S609 VanDerWaalsContact OG-CB 3.26Å; S605-S609 WeakPolarHBondContact OG-CB 3.37Å; S605-S609 PolarHBondContact OG-N 2.56Å; S605-S609 PolarHBondContact OG-OG 2.74Å; E607-S609 PolarHBondContact O-N 2.84Å
610L92.2Very high79.3Confident0 Ų060.6 Ų60.60%032%0.317CS..EExtended strand (participates in β ladder)trans-83.8118.6171.8179.660.4000109.1M570 W588 V595 F597 H602 I612 Y635M570-L610 HydrophobicContact CE-CB 4.23Å; M570-L610 HydrophobicContact CE-CD2 3.65Å; M570-L610 HydrophobicContact CE-CG 3.94Å; M570-L610 PolarHBondContact N-O 2.87Å; M570-L610 PolarHBondContact O-N 3.14Å; W588-L610 HydrophobicContact CB-CD2 4.32Å; W588-L610 HydrophobicContact CD2-CB 3.65Å; W588-L610 HydrophobicContact CD2-CD2 3.95Å; W588-L610 HydrophobicContact CD2-CG 4.41Å; W588-L610 VanDerWaalsContact CE2-CB 3.48Å; W588-L610 HydrophobicContact CE3-CB 4.08Å; W588-L610 HydrophobicContact CE3-CD2 3.86Å; W588-L610 HydrophobicContact CG-CB 4.06Å; W588-L610 HydrophobicContact CG-CD2 4.18Å; W588-L610 HydrophobicContact CH2-CB 4.16Å; W588-L610 HydrophobicContact CZ2-CB 3.74Å; W588-L610 HydrophobicContact CZ3-CB 4.32Å; W588-L610 HydrophobicContact CZ3-CD2 4.44Å; V595-L610 HydrophobicContact CG1-CD1 4.24Å; V595-L610 HydrophobicContact CG2-CD2 4.2Å; F597-L610 HydrophobicContact CE1-CD1 3.63Å; F597-L610 HydrophobicContact CZ-CD1 4.19Å; H602-L610 HydrophobicContact CB-CD1 4.15Å; L610-I612 HydrophobicContact CD2-CD1 4.44Å; L610-I612 HydrophobicContact CD2-CG1 4.49Å; L610-I612 HydrophobicContact CG-CG1 4.16Å; L610-Y635 HydrophobicContact CD2-CD1 3.44Å; L610-Y635 VanDerWaalsContact CD2-CD1 3.44Å; L610-Y635 HydrophobicContact CD2-CE1 3.99Å; L610-Y635 HydrophobicContact CD2-CG 4.3Å
611I92Very high78Confident54 Ų5467.2 Ų67.228%0.27734%0.335SS..EExtended strand (participates in β ladder)trans-104.5126.1173.9-57.4169000106.9I568 F603 I613I568-I611 CarbonylContact O-C 3.55Å; I568-I611 WeakPolarHBondContact O-CA 3.35Å; F603-I611 HydrophobicContact CB-CB 4.2Å; F603-I611 PolarHBondContact N-O 3.37Å; F603-I611 PolarHBondContact O-N 3.3Å; I611-I613 HydrophobicContact CG2-CG2 4.09Å
612I91.2Very high76.5Confident4 Ų467.6 Ų67.62%0.02134%0.342CS..EExtended strand (participates in β ladder)trans-113.8122.8172.3-47.8-179.4000106.4S567 I568 M570 R601 L610 V615 Y635 L649S567-I612 CarbonylContact C-O 3.5Å; S567-I612 WeakPolarHBondContact CA-O 3.24Å; I568-I612 HydrophobicContact CG2-CB 4.02Å; I568-I612 HydrophobicContact CG2-CD1 4.41Å; I568-I612 HydrophobicContact CG2-CG1 4.3Å; I568-I612 PolarHBondContact N-O 2.71Å; I568-I612 PolarHBondContact O-N 2.97Å; M570-I612 HydrophobicContact CE-CD1 3.59Å; M570-I612 HydrophobicContact CE-CG1 4.08Å; R601-I612 WeakPolarHBondContact O-CA 3.49Å; L610-I612 HydrophobicContact CD2-CD1 4.44Å; L610-I612 HydrophobicContact CD2-CG1 4.49Å; L610-I612 HydrophobicContact CG-CG1 4.16Å; I612-V615 HydrophobicContact CB-CG2 4.09Å; I612-V615 HydrophobicContact CG2-CG2 3.65Å; I612-Y635 HydrophobicContact CD1-CD1 4.29Å; I612-Y635 HydrophobicContact CD1-CE1 3.7Å; I612-Y635 HydrophobicContact CD1-CE2 4.12Å; I612-L649 HydrophobicContact CD1-CD1 3.87Å
613I87Confident74.8Confident57 Ų5770 Ų7029%0.29236%0.362SS..  trans-106.1151.8173.864.5177000110S567 R601 F603 I611 V615S567-I613 WeakPolarHBondContact OG-CA 3.39Å; R601-I613 PolarHBondContact O-N 3.36Å; F603-I613 HydrophobicContact CD2-CD1 4.14Å; F603-I613 HydrophobicContact CD2-CG1 4.16Å; F603-I613 HydrophobicContact CE2-CD1 3.29Å; F603-I613 HydrophobicContact CE2-CG1 3.58Å; F603-I613 HydrophobicContact CZ-CD1 3.83Å; I611-I613 HydrophobicContact CG2-CG2 4.09Å; I613-V615 VanDerWaalsContact C-N 3.33Å; I613-V615 PolarHBondContact O-N 2.05Å
614N81.7Confident73.1Confident84 Ų8470 Ų7045%0.44937%0.369SS..SBendtrans49.853177.6-66.4-28.6000112.3D566 C616 T617D566-N614 PolarHBondContact O-N 2.99Å; N614-C616 PolarHBondContact O-N 2.8Å; N614-T617 HydrophobicContact CB-CG2 3.9Å; N614-T617 WeakPolarHBondContact CB-OG1 3.38Å; N614-T617 PolarHBondContact O-N 3.09Å; N614-T617 PolarHBondContact O-OG1 2.83Å
615V84.7Confident71.7Confident2 Ų268.4 Ų68.41%0.01237%0.368CS..THydrogen-bonded Turntrans-54.6129.4-1781730000109.8L562 P564 G565 D566 I568 I612 I613 T617 C631 I651L562-V615 HydrophobicContact CD1-CG1 4.39Å; L562-V615 HydrophobicContact CD1-CG2 4.24Å; P564-V615 CarbonylContact C-O 3.5Å; P564-V615 VanDerWaalsContact CA-O 3.29Å; P564-V615 WeakPolarHBondContact CA-O 3.45Å; G565-V615 PolarHBondContact N-O 2.82Å; D566-V615 WeakPolarHBondContact O-CB 3.47Å; D566-V615 VanDerWaalsContact O-CG2 3.23Å; D566-V615 WeakPolarHBondContact O-CG2 3.11Å; D566-V615 PolarHBondContact O-N 2.8Å; I568-V615 HydrophobicContact CG2-CG2 4.49Å; I612-V615 HydrophobicContact CB-CG2 4.09Å; I612-V615 HydrophobicContact CG2-CG2 3.65Å; I613-V615 VanDerWaalsContact C-N 3.33Å; I613-V615 PolarHBondContact O-N 2.05Å; V615-T617 PolarHBondContact O-N 2.8Å; V615-C631 HydrophobicContact CG1-CB 4.48Å; V615-I651 HydrophobicContact CG1-CD1 3.45Å; V615-I651 VanDerWaalsContact CG1-CD1 3.45Å
616C77.7Confident70.7Confident4 Ų468.7 Ų68.73%0.02737%0.372CS..THydrogen-bonded Turntrans54.720.1178.3-53.30000116.7P564 N614 T628 C631 I651P564-C616 HydrophobicContact CB-CB 4.4Å; N614-C616 PolarHBondContact O-N 2.8Å; C616-T628 HydrophobicContact CB-CG2 4.22Å; C616-C631 WeakPolarHBondContact SG-CB 3.44Å; C616-C631 VanDerWaalsContact SG-SG 3.64Å; C616-I651 HydrophobicContact CB-CG2 4.32Å
617T69.4Low70.2Confident44 Ų4462.1 Ų62.127%0.2733%0.333SS..  trans-74.8135.9174.562.50000110.5G565 N614 V615 H619G565-T617 VanDerWaalsContact CA-CG2 3.46Å; N614-T617 HydrophobicContact CB-CG2 3.9Å; N614-T617 WeakPolarHBondContact CB-OG1 3.38Å; N614-T617 PolarHBondContact O-N 3.09Å; N614-T617 PolarHBondContact O-OG1 2.83Å; V615-T617 PolarHBondContact O-N 2.8Å; T617-H619 PolarHBondContact O-N 3.11Å; T617-H619 VanDerWaalsContact O-N 3.16Å
618V61.5Low69.8Low64 Ų6458.4 Ų58.439%0.38832%0.316SS..  trans-73.6106.5-179.8-173.60000108.8F620 L622 T624 A627V618-F620 PolarHBondContact O-N 2.93Å; V618-L622 HydrophobicContact CG1-CB 4.26Å; V618-L622 WeakPolarHBondContact CG1-O 2.97Å; V618-T624 HydrophobicContact CG2-CG2 4.18Å; V618-A627 HydrophobicContact CG2-CB 4.44Å
619H53.9Low69.2Low166 Ų16666.1 Ų66.177%0.76935%0.35SS*.  trans-75.9118.5154.5-106.7-73.1000107.2T617T617-H619 PolarHBondContact O-N 3.11Å; T617-H619 VanDerWaalsContact O-N 3.16Å
620F47Very low68.5Low195 Ų19571 Ų7186%0.85537%0.372SS*.SBendtrans12.1109.1169-111.7-99.4000115.4V618V618-F620 PolarHBondContact O-N 2.93Å
621Q52.7Low67.9Low188 Ų18871.6 Ų71.688%0.87938%0.376SS*.SBendtrans99.34.3168-53177.8-3300119.8
622L50.5Low67.7Low78 Ų7870.5 Ų70.541%0.40838%0.375SS..  trans-102.9151.8167-115.278.2000112.7V618 A626V618-L622 HydrophobicContact CG1-CB 4.26Å; V618-L622 WeakPolarHBondContact CG1-O 2.97Å; L622-A626 HydrophobicContact CD2-CB 3.58Å; L622-A626 HydrophobicContact CG-CB 3.88Å
623S54.6Low67.7Low73 Ų7370.9 Ų70.951%0.5138%0.38SS..  trans-76.3152.7166.666.10000110.3A625 A626 A627S623-A625 PolarHBondContact O-N 3.42Å; S623-A626 PolarHBondContact O-N 3.22Å; S623-A626 PolarHBondContact OG-N 3.36Å; S623-A627 PolarHBondContact O-N 3.49Å; S623-A627 VanDerWaalsContact O-N 3.08Å
624T56Low68Low92 Ų9269.4 Ų69.456%0.56438%0.375SS*.Hα-helixtrans-53.4-40.7176.448.30000111.9V618 A626 A627 T628V618-T624 HydrophobicContact CG2-CG2 4.18Å; T624-A626 VanDerWaalsContact C-N 3.34Å; T624-A626 PolarHBondContact O-N 3.42Å; T624-A627 PolarHBondContact O-N 3.14Å; T624-T628 WeakPolarHBondContact O-CG2 3.48Å; T624-T628 PolarHBondContact O-N 2.64Å; T624-T628 PolarHBondContact O-OG1 3.31Å
625A58.1Low68.5Low50 Ų5065.5 Ų65.541%0.41335%0.354SS..Hα-helixtrans-67.2-27.5177.900000114.4S623 T628S623-A625 PolarHBondContact O-N 3.42Å; A625-T628 WeakPolarHBondContact CA-OG1 3.46Å; A625-T628 PolarHBondContact O-OG1 3.07Å; A625-T628 VanDerWaalsContact O-OG1 3.12Å
626A61.7Low68.9Low36 Ų3665.9 Ų65.930%0.29836%0.355SS..Hα-helixtrans-77.8-42.2174.100000110.6L622 S623 T624 T628 K629 E630L622-A626 HydrophobicContact CD2-CB 3.58Å; L622-A626 HydrophobicContact CG-CB 3.88Å; S623-A626 PolarHBondContact O-N 3.22Å; S623-A626 PolarHBondContact OG-N 3.36Å; T624-A626 VanDerWaalsContact C-N 3.34Å; T624-A626 PolarHBondContact O-N 3.42Å; A626-T628 VanDerWaalsContact C-N 3.35Å; A626-T628 PolarHBondContact O-N 2.9Å; A626-K629 PolarHBondContact O-N 2.92Å; A626-E630 PolarHBondContact O-N 2.92Å
627A63Low69.4Low3 Ų365.7 Ų65.73%0.02535%0.354CS..Hα-helixtrans-64.3-38.4177.200000112.1V618 S623 T624 E630 C631V618-A627 HydrophobicContact CG2-CB 4.44Å; S623-A627 PolarHBondContact O-N 3.49Å; S623-A627 VanDerWaalsContact O-N 3.08Å; T624-A627 PolarHBondContact O-N 3.14Å; A627-E630 PolarHBondContact O-N 2.71Å; A627-C631 PolarHBondContact O-N 3.48Å; A627-C631 PolarHBondContact O-SG 2.87Å
628T62.9Low70.1Confident15 Ų1564.7 Ų64.79%0.09235%0.348CS..Hα-helixtrans-65.6-38.6177.556.40000112.5C616 T624 A625 A626 E630 A632 I651 D653C616-T628 HydrophobicContact CB-CG2 4.22Å; T624-T628 WeakPolarHBondContact O-CG2 3.48Å; T624-T628 PolarHBondContact O-N 2.64Å; T624-T628 PolarHBondContact O-OG1 3.31Å; A625-T628 WeakPolarHBondContact CA-OG1 3.46Å; A625-T628 PolarHBondContact O-OG1 3.07Å; A625-T628 VanDerWaalsContact O-OG1 3.12Å; A626-T628 VanDerWaalsContact C-N 3.35Å; A626-T628 PolarHBondContact O-N 2.9Å; T628-E630 VanDerWaalsContact C-N 3.28Å; T628-E630 PolarHBondContact O-N 2.63Å; T628-A632 WeakPolarHBondContact O-CB 3.02Å; T628-A632 PolarHBondContact O-N 2.96Å; T628-I651 HydrophobicContact CG2-CG2 3.82Å; T628-D653 HydrophobicContact CG2-CB 3.71Å; T628-D653 PolarHBondContact OG1-OD2 3.15Å
629K67.6Low70.9Confident177 Ų17763.3 Ų63.377%0.7734%0.337SS*.Hα-helixtrans-65.6-27.5173-77.9-175.3179.9-179.30113.8A626A626-K629 PolarHBondContact O-N 2.92Å
630E73.4Confident71.7Confident105 Ų10561.3 Ų61.349%0.49133%0.328SS..Hα-helixtrans-78.6-31179.8-78-172.7171.400113.5F590 A626 A627 T628F590-E630 WeakPolarHBondContact CE1-O 3.32Å; F590-E630 WeakPolarHBondContact CZ-O 3.47Å; A626-E630 PolarHBondContact O-N 2.92Å; A627-E630 PolarHBondContact O-N 2.71Å; T628-E630 VanDerWaalsContact C-N 3.28Å; T628-E630 PolarHBondContact O-N 2.63Å
631C79.5Confident72.9Confident12 Ų1263.7 Ų63.78%0.08133%0.331CS..Hα-helixtrans-104.8-21.9-178.4-35.90000114V615 C616 A627 Y635V615-C631 HydrophobicContact CG1-CB 4.48Å; C616-C631 WeakPolarHBondContact SG-CB 3.44Å; C616-C631 VanDerWaalsContact SG-SG 3.64Å; A627-C631 PolarHBondContact O-N 3.48Å; A627-C631 PolarHBondContact O-SG 2.87Å; C631-Y635 WeakPolarHBondContact O-CE2 3.37Å; C631-Y635 PolarHBondContact O-OH 2.69Å
632A87.9Confident73.9Confident31 Ų3157.1 Ų57.126%0.25630%0.304SS..  trans-70.7133.1173.200000110.2T628 I651T628-A632 WeakPolarHBondContact O-CB 3.02Å; T628-A632 PolarHBondContact O-N 2.96Å; A632-I651 HydrophobicContact CB-CB 4.39Å; A632-I651 HydrophobicContact CB-CG1 3.72Å
633G91Very high75.2Confident13 Ų1357.5 Ų57.513%0.13430%0.302CS..EExtended strand (participates in β ladder)trans151.4-164.5-179.500000114L649G633-L649 PolarHBondContact N-O 2.74Å; G633-L649 VanDerWaalsContact N-O 3.1Å; G633-L649 PolarHBondContact O-N 3.29Å
634S92.8Very high76.2Confident26 Ų2655.5 Ų55.518%0.18229%0.286CS..EExtended strand (participates in β ladder)trans-97.3117.1-173.2-175.90000111.1F590 N591 Y647F590-S634 CarbonylContact C-O 3.58Å; F590-S634 WeakPolarHBondContact CA-O 2.99Å; N591-S634 PolarHBondContact N-O 2.98Å; N591-S634 PolarHBondContact OD1-N 3.4Å; S634-Y647 CarbonylContact C-O 3.48Å; S634-Y647 WeakPolarHBondContact CA-O 3.28Å
635Y93.6Very high77.4Confident2 Ų251.3 Ų51.31%0.00826%0.26CS..EExtended strand (participates in β ladder)trans-101120.7169.5-68.3-97.8000109.5M570 L589 F590 V595 H602 L610 I612 C631 Y647 L649M570-Y635 HydrophobicContact CE-CD1 4.14Å; M570-Y635 HydrophobicContact CE-CD2 4.31Å; M570-Y635 HydrophobicContact CE-CG 3.88Å; L589-Y635 CarbonylContact O-C 3.53Å; L589-Y635 VanDerWaalsContact O-CA 3.26Å; L589-Y635 WeakPolarHBondContact O-CA 3.24Å; F590-Y635 HydrophobicContact CB-CD1 3.99Å; F590-Y635 HydrophobicContact CB-CE1 3.77Å; F590-Y635 AromaticContact CD2-CD1 3.98Å; F590-Y635 HydrophobicContact CD2-CD1 3.98Å; F590-Y635 AromaticContact CD2-CD2 3.76Å; F590-Y635 HydrophobicContact CD2-CD2 3.76Å; F590-Y635 AromaticContact CD2-CE1 3.57Å; F590-Y635 HydrophobicContact CD2-CE1 3.57Å; F590-Y635 AromaticContact CD2-CE2 3.3Å; F590-Y635 HydrophobicContact CD2-CE2 3.3Å; F590-Y635 HydrophobicContact CD2-CG 4.08Å; F590-Y635 AromaticContact CD2-CZ 3.21Å; F590-Y635 HydrophobicContact CE2-CD2 4.2Å; F590-Y635 HydrophobicContact CE2-CE1 4.4Å; F590-Y635 AromaticContact CE2-CE2 3.47Å; F590-Y635 HydrophobicContact CE2-CE2 3.47Å; F590-Y635 VanDerWaalsContact CE2-CE2 3.47Å; F590-Y635 AromaticContact CE2-CZ 3.6Å; F590-Y635 HydrophobicContact CG-CD1 4.38Å; F590-Y635 AromaticContact CG-CE1 3.88Å; F590-Y635 HydrophobicContact CG-CE1 3.88Å; F590-Y635 HydrophobicContact CG-CE2 4.36Å; F590-Y635 AromaticContact CG-CZ 3.86Å; V595-Y635 HydrophobicContact CG2-CD1 4.18Å; V595-Y635 HydrophobicContact CG2-CE1 4.31Å; H602-Y635 AromaticContact NE2-CE1 3.61Å; H602-Y635 AromaticContact NE2-CZ 3.95Å; H602-Y635 PolarHBondContact NE2-OH 2.95Å; L610-Y635 HydrophobicContact CD2-CD1 3.44Å; L610-Y635 VanDerWaalsContact CD2-CD1 3.44Å; L610-Y635 HydrophobicContact CD2-CE1 3.99Å; L610-Y635 HydrophobicContact CD2-CG 4.3Å; I612-Y635 HydrophobicContact CD1-CD1 4.29Å; I612-Y635 HydrophobicContact CD1-CE1 3.7Å; I612-Y635 HydrophobicContact CD1-CE2 4.12Å; C631-Y635 WeakPolarHBondContact O-CE2 3.37Å; C631-Y635 PolarHBondContact O-OH 2.69Å; Y635-Y647 PolarHBondContact N-O 2.88Å; Y635-Y647 PolarHBondContact O-N 3.49Å; Y635-L649 HydrophobicContact CD2-CD1 3.69Å; Y635-L649 HydrophobicContact CD2-CG 3.8Å; Y635-L649 HydrophobicContact CE2-CB 4.43Å; Y635-L649 HydrophobicContact CE2-CD1 3.47Å; Y635-L649 VanDerWaalsContact CE2-CD1 3.47Å; Y635-L649 HydrophobicContact CE2-CG 3.94Å
636E91.3Very high78.9Confident9 Ų949.1 Ų49.14%0.04224%0.242CC..EExtended strand (participates in β ladder)trans-123.3130-176.8-57.6-171.5149.500110.1W588 L589 V638 K643 V645W588-E636 CarbonylContact C-O 3.58Å; W588-E636 WeakPolarHBondContact CA-O 3.24Å; L589-E636 PolarHBondContact N-O 3.2Å; L589-E636 PolarHBondContact O-N 2.99Å; E636-V638 HydrophobicContact CB-CG2 4.23Å; E636-K643 IonicContact OE1-NZ 3.97Å; E636-K643 PolarHBondContact OE1-NZ 3.04Å; E636-K643 WeakPolarHBondContact OE2-CE 3.43Å; E636-K643 IonicContact OE2-NZ 3.92Å; E636-K643 PolarHBondContact OE2-NZ 3.08Å; E636-V645 WeakPolarHBondContact CA-O 3.43Å
637C88.6Confident80.3Confident0 Ų047.9 Ų47.90%023%0.229CC..EExtended strand (participates in β ladder)trans-93.9125.4169.2-158.80000109.1C572 W588 L644 V645C572-C637 HydrophobicContact CB-CB 3.77Å; C572-C637 WeakPolarHBondContact CB-SG 3.41Å; C572-C637 WeakPolarHBondContact SG-CB 3.37Å; C572-C637 CovalentContact SG-SG 2.01Å; C572-C637 PolarHBondContact SG-SG 3.18Å; W588-C637 HydrophobicContact CD2-CB 3.96Å; W588-C637 HydrophobicContact CE3-CB 3.99Å; W588-C637 HydrophobicContact CH2-CB 3.96Å; W588-C637 HydrophobicContact CZ2-CB 3.92Å; W588-C637 HydrophobicContact CZ3-CB 3.99Å; C637-L644 PolarHBondContact O-N 2.99Å; C637-V645 HydrophobicContact CB-CG1 3.64Å; C637-V645 PolarHBondContact N-O 3.05Å
638V85.3Confident81.8Confident24 Ų2450.1 Ų50.115%0.14524%0.241CC..EExtended strand (participates in β ladder)trans-128.7136.5-171.8-176.20000110.2P586 V587 L589 E636 T642 K643P586-V638 WeakPolarHBondContact CA-O 3.33Å; V587-V638 PolarHBondContact N-O 3.23Å; V587-V638 PolarHBondContact O-N 3.47Å; L589-V638 HydrophobicContact CD1-CB 4.43Å; L589-V638 HydrophobicContact CD1-CG2 3.77Å; L589-V638 HydrophobicContact CG-CG2 4.3Å; E636-V638 HydrophobicContact CB-CG2 4.23Å; V638-T642 WeakPolarHBondContact CA-O 3.38Å; V638-T642 WeakPolarHBondContact CG1-O 3.31Å; V638-K643 HydrophobicContact CG2-CG 4.22Å
639Q77.6Confident83.2Confident35 Ų3549.4 Ų49.416%0.16424%0.237CC..EExtended strand (participates in β ladder)trans-135.2131.3172.1-159.2-162.424.400109.7Q574 P586 R641 T642 L644Q574-Q639 VanDerWaalsContact CD-OE1 3.27Å; P586-Q639 HydrophobicContact CB-CB 4.22Å; P586-Q639 HydrophobicContact CB-CG 4.46Å; Q639-R641 PolarHBondContact O-N 2.83Å; Q639-T642 PolarHBondContact N-O 2.85Å; Q639-T642 WeakPolarHBondContact O-CA 3.28Å; Q639-T642 VanDerWaalsContact O-CB 3.3Å; Q639-T642 WeakPolarHBondContact O-CB 3.43Å; Q639-T642 PolarHBondContact O-N 2.85Å; Q639-L644 HydrophobicContact CB-CD1 3.83Å; Q639-L644 HydrophobicContact CB-CG 4.28Å
640H71.2Confident84.3Confident123 Ų12344.9 Ų44.957%0.56922%0.22SC*.THydrogen-bonded Turntrans4941.8-178.7-54.8105000114T642H640-T642 PolarHBondContact O-N 2.86Å
641R71.9Confident84.9Confident246 Ų24641 Ų4193%0.92820%0.203SC*.THydrogen-bonded Turntrans68.12.7-175.3-51.3179175.4-176.9-1.5115.7Q639Q639-R641 PolarHBondContact O-N 2.83Å
642T73.1Confident85.1Confident49 Ų4942.1 Ų42.130%0.30121%0.208SC..EExtended strand (participates in β ladder)trans-94.7124.5175.5-640000110.5V552 V638 Q639 H640 L644V552-T642 HydrophobicContact CB-CG2 4.34Å; V552-T642 HydrophobicContact CG1-CG2 3.15Å; V552-T642 HydrophobicContact CG2-CG2 4.24Å; V638-T642 WeakPolarHBondContact CA-O 3.38Å; V638-T642 WeakPolarHBondContact CG1-O 3.31Å; Q639-T642 PolarHBondContact N-O 2.85Å; Q639-T642 WeakPolarHBondContact O-CA 3.28Å; Q639-T642 VanDerWaalsContact O-CB 3.3Å; Q639-T642 WeakPolarHBondContact O-CB 3.43Å; Q639-T642 PolarHBondContact O-N 2.85Å; H640-T642 PolarHBondContact O-N 2.86Å; T642-L644 HydrophobicContact CG2-CD2 4.49Å; T642-L644 PolarHBondContact O-N 2.74Å
643K78.3Confident84.5Confident87 Ų8742.8 Ų42.838%0.37821%0.207SC..EExtended strand (participates in β ladder)trans-70.2124.4171.2-63.5-174-175.5-163.70108.9V555 E636 V638V555-K643 HydrophobicContact CG2-CB 4.03Å; V555-K643 WeakPolarHBondContact CG2-O 3.38Å; E636-K643 IonicContact OE1-NZ 3.97Å; E636-K643 PolarHBondContact OE1-NZ 3.04Å; E636-K643 WeakPolarHBondContact OE2-CE 3.43Å; E636-K643 IonicContact OE2-NZ 3.92Å; E636-K643 PolarHBondContact OE2-NZ 3.08Å; V638-K643 HydrophobicContact CG2-CG 4.22Å
644L76Confident83.5Confident31 Ų3146.9 Ų46.916%0.16223%0.229CC..EExtended strand (participates in β ladder)trans-92.4-41.2178.9-60.3179.3000111.3T510 Q574 P586 C637 Q639 T642T510-L644 HydrophobicContact CG2-CD2 4.38Å; Q574-L644 HydrophobicContact CG-CD1 3.99Å; P586-L644 HydrophobicContact CB-CD1 3.94Å; C637-L644 PolarHBondContact O-N 2.99Å; Q639-L644 HydrophobicContact CB-CD1 3.83Å; Q639-L644 HydrophobicContact CB-CG 4.28Å; T642-L644 HydrophobicContact CG2-CD2 4.49Å; T642-L644 PolarHBondContact O-N 2.74Å
645V81.7Confident82.3Confident3 Ų349.3 Ų49.32%0.01825%0.246CC..EExtended strand (participates in β ladder)trans-151.7150.9176.567.30000109.6I558 W588 E636 C637 Y647I558-V645 HydrophobicContact CD1-CG2 4.04Å; W588-V645 HydrophobicContact CH2-CG1 3.9Å; W588-V645 HydrophobicContact CZ3-CG1 4.36Å; E636-V645 WeakPolarHBondContact CA-O 3.43Å; C637-V645 HydrophobicContact CB-CG1 3.64Å; C637-V645 PolarHBondContact N-O 3.05Å; V645-Y647 HydrophobicContact CB-CE2 4.21Å; V645-Y647 HydrophobicContact CG1-CD2 4.15Å; V645-Y647 HydrophobicContact CG1-CE2 3.75Å; V645-Y647 HydrophobicContact CG2-CD2 3.9Å; V645-Y647 HydrophobicContact CG2-CE2 3.38Å
646S88Confident81Confident4 Ų453 Ų533%0.02827%0.272CS..EExtended strand (participates in β ladder)trans-131122.8175177.60000109.4R557 I558R557-S646 CarbonylContact C-O 3.59Å; R557-S646 WeakPolarHBondContact CA-O 3.39Å; I558-S646 PolarHBondContact N-O 3.44Å
647Y92Very high80Confident10 Ų1057.7 Ų57.74%0.03930%0.297CS..EExtended strand (participates in β ladder)trans-110.2132.9174.3-71.3-91.1000109.3I558 K560 M570 N571 W588 S634 Y635 V645I558-Y647 HydrophobicContact CB-CD1 3.75Å; I558-Y647 HydrophobicContact CB-CE1 3.93Å; I558-Y647 HydrophobicContact CB-CG 4.46Å; I558-Y647 HydrophobicContact CD1-CD1 4.35Å; I558-Y647 HydrophobicContact CD1-CE1 3.73Å; I558-Y647 HydrophobicContact CG1-CE1 4.43Å; I558-Y647 HydrophobicContact CG2-CD1 3.86Å; I558-Y647 HydrophobicContact CG2-CE1 3.83Å; I558-Y647 CarbonylContact O-C 3.59Å; I558-Y647 VanDerWaalsContact O-CA 3.31Å; I558-Y647 WeakPolarHBondContact O-CA 3.33Å; K560-Y647 HydrophobicContact CG-CD1 4.42Å; M570-Y647 HydrophobicContact CB-CD1 4.32Å; M570-Y647 HydrophobicContact CB-CD2 3.82Å; M570-Y647 HydrophobicContact CB-CE1 4.16Å; M570-Y647 HydrophobicContact CB-CE2 3.62Å; M570-Y647 HydrophobicContact CB-CG 4.16Å; M570-Y647 HydrophobicContact CG-CD1 3.81Å; M570-Y647 HydrophobicContact CG-CD2 4.05Å; M570-Y647 HydrophobicContact CG-CE1 3.95Å; M570-Y647 HydrophobicContact CG-CE2 4.18Å; M570-Y647 HydrophobicContact CG-CG 3.86Å; M570-Y647 WeakPolarHBondContact SD-CB 3.27Å; M570-Y647 HydrophobicContact SD-CD1 3.84Å; M570-Y647 HydrophobicContact SD-CD2 3.88Å; M570-Y647 HydrophobicContact SD-CG 3.45Å; N571-Y647 PolarHBondContact N-OH 3.04Å; N571-Y647 PolarHBondContact O-OH 2.76Å; W588-Y647 HydrophobicContact CH2-CD2 4Å; W588-Y647 AromaticContact CH2-CE2 3.95Å; W588-Y647 HydrophobicContact CH2-CE2 3.95Å; W588-Y647 HydrophobicContact CZ3-CD2 4.08Å; W588-Y647 HydrophobicContact CZ3-CE2 4.48Å; S634-Y647 CarbonylContact C-O 3.48Å; S634-Y647 WeakPolarHBondContact CA-O 3.28Å; Y635-Y647 PolarHBondContact N-O 2.88Å; Y635-Y647 PolarHBondContact O-N 3.49Å; V645-Y647 HydrophobicContact CB-CE2 4.21Å; V645-Y647 HydrophobicContact CG1-CD2 4.15Å; V645-Y647 HydrophobicContact CG1-CE2 3.75Å; V645-Y647 HydrophobicContact CG2-CD2 3.9Å; V645-Y647 HydrophobicContact CG2-CE2 3.38Å
648N93.4Very high79.2Confident50 Ų5067.9 Ų67.927%0.26734%0.336SS..EExtended strand (participates in β ladder)trans-111.2107.4172.6-173.750.5000108.5I558 T559 K560I558-N648 PolarHBondContact O-N 2.88Å; T559-N648 CarbonylContact C-O 3.54Å; T559-N648 VanDerWaalsContact CA-O 3.31Å; T559-N648 WeakPolarHBondContact CA-O 3.42Å; K560-N648 PolarHBondContact N-O 2.78Å
649L92.9Very high78.9Confident1 Ų168.8 Ų68.81%0.00534%0.342CS..EExtended strand (participates in β ladder)trans-88.7117.9179.6-57.8-168.5000109.4K560 L562 I568 M570 I612 G633 Y635K560-L649 HydrophobicContact CB-CD2 3.69Å; K560-L649 HydrophobicContact CG-CD2 4.35Å; L562-L649 HydrophobicContact CD1-CD1 4.04Å; L562-L649 HydrophobicContact CD1-CD2 4.04Å; L562-L649 HydrophobicContact CD1-CG 4.46Å; I568-L649 HydrophobicContact CD1-CD2 4Å; I568-L649 HydrophobicContact CG2-CD1 4.42Å; M570-L649 HydrophobicContact CE-CD1 4.26Å; M570-L649 HydrophobicContact SD-CD1 4.25Å; M570-L649 HydrophobicContact SD-CD2 3.91Å; M570-L649 HydrophobicContact SD-CG 4.33Å; I612-L649 HydrophobicContact CD1-CD1 3.87Å; G633-L649 PolarHBondContact N-O 2.74Å; G633-L649 VanDerWaalsContact N-O 3.1Å; G633-L649 PolarHBondContact O-N 3.29Å; Y635-L649 HydrophobicContact CD2-CD1 3.69Å; Y635-L649 HydrophobicContact CD2-CG 3.8Å; Y635-L649 HydrophobicContact CE2-CB 4.43Å; Y635-L649 HydrophobicContact CE2-CD1 3.47Å; Y635-L649 VanDerWaalsContact CE2-CD1 3.47Å; Y635-L649 HydrophobicContact CE2-CG 3.94Å
650L90.3Very high79.2Confident81 Ų8175.6 Ų75.642%0.42437%0.374SS..EExtended strand (participates in β ladder)trans-101.1131169.8-59.1-180000107.8T559 K560 L561 L562T559-L650 HydrophobicContact CG2-CD1 3.49Å; T559-L650 VanDerWaalsContact CG2-CD1 3.49Å; T559-L650 HydrophobicContact CG2-CG 3.81Å; K560-L650 PolarHBondContact O-N 2.55Å; L561-L650 CarbonylContact C-O 3.59Å; L561-L650 WeakPolarHBondContact CA-O 3.39Å; L561-L650 HydrophobicContact CD1-CB 3.9Å; L562-L650 PolarHBondContact N-O 2.93Å
651I87.2Confident79.9Confident24 Ų2472.8 Ų72.812%0.12337%0.368CS..EExtended strand (participates in β ladder)trans-110.3120.1179.3-49.7-60.4000108.1L562 P564 V615 C616 T628 A632L562-I651 HydrophobicContact CB-CD1 3.86Å; L562-I651 HydrophobicContact CD1-CD1 4.44Å; L562-I651 VanDerWaalsContact O-CA 3.31Å; L562-I651 WeakPolarHBondContact O-CA 3.17Å; P564-I651 HydrophobicContact CG-CG2 4.19Å; V615-I651 HydrophobicContact CG1-CD1 3.45Å; V615-I651 VanDerWaalsContact CG1-CD1 3.45Å; C616-I651 HydrophobicContact CB-CG2 4.32Å; T628-I651 HydrophobicContact CG2-CG2 3.82Å; A632-I651 HydrophobicContact CB-CB 4.39Å; A632-I651 HydrophobicContact CB-CG1 3.72Å
652D82.7Confident80.6Confident35 Ų3567 Ų6719%0.18736%0.355CS..  trans-96100.3172.3-174.5-4.2000109.8L561 L562 Y563 P564 V654 S655L561-D652 HydrophobicContact CD1-CB 4.02Å; L562-D652 PolarHBondContact O-N 3.44Å; Y563-D652 HydrophobicContact CD1-CB 4.08Å; Y563-D652 WeakPolarHBondContact CD1-O 3.22Å; Y563-D652 HydrophobicContact CE1-CB 3.88Å; P564-D652 WeakPolarHBondContact CD-O 3.35Å; D652-V654 PolarHBondContact OD1-N 2.94Å; D652-S655 PolarHBondContact OD1-N 3.34Å; D652-S655 PolarHBondContact OD1-OG 3.38Å; D652-S655 WeakPolarHBondContact OD2-CB 3.41Å; D652-S655 PolarHBondContact OD2-OG 2.96Å
653D74.9Confident81.1Confident45 Ų4572.7 Ų72.724%0.24138%0.378CS..  trans-91.6-12.2172.561.3-8.5000113P564 T628P564-D653 HydrophobicContact CG-CB 4.28Å; T628-D653 HydrophobicContact CG2-CB 3.71Å; T628-D653 PolarHBondContact OG1-OD2 3.15Å
654V70.7Confident81.3Confident99 Ų9970.3 Ų70.360%0.637%0.374SS*.SBendtrans-82.2-44.7-174.8-176.80000110.8D652 C656 N657D652-V654 PolarHBondContact OD1-N 2.94Å; V654-C656 PolarHBondContact O-N 3.07Å; V654-N657 WeakPolarHBondContact O-CB 3.46Å; V654-N657 PolarHBondContact O-N 2.83Å; V654-N657 PolarHBondContact O-ND2 3.41Å
655S68.2Low81.7Confident77 Ų7773.8 Ų73.854%0.53839%0.388SS..THydrogen-bonded Turntrans-70.3-18178.5-56.70000112.9D652 N657D652-S655 PolarHBondContact OD1-N 3.34Å; D652-S655 PolarHBondContact OD1-OG 3.38Å; D652-S655 WeakPolarHBondContact OD2-CB 3.41Å; D652-S655 PolarHBondContact OD2-OG 2.96Å; S655-N657 PolarHBondContact O-N 2.88Å
656C66Low81.8Confident81 Ų8178.4 Ų78.455%0.54741%0.409SS..THydrogen-bonded Turntrans-77.2-3.7175.4-153.50000113V654V654-C656 PolarHBondContact O-N 3.07Å
657N69.7Low81.6Confident107 Ų10781.5 Ų81.557%0.57243%0.431SS*.SBendtrans-70.2153.3176.8-71.7-51.3000112.3V654 S655V654-N657 WeakPolarHBondContact O-CB 3.46Å; V654-N657 PolarHBondContact O-N 2.83Å; V654-N657 PolarHBondContact O-ND2 3.41Å; S655-N657 PolarHBondContact O-N 2.88Å
658R72.7Confident81Confident214 Ų21484.5 Ų84.581%0.80845%0.45SS*.PPolyproline II helixtrans-54.8126.1175.7-178.2178.8178.5171.90.7110.4Q660R658-Q660 PolarHBondContact O-N 3.29Å; R658-Q660 PolarHBondContact O-NE2 2.03Å; R658-Q660 VanDerWaalsContact O-NE2 3.07Å
659P78.7Confident80.6Confident43 Ų4388.7 Ų88.728%0.27946%0.463SS..PPolyproline II helixtrans-61.5132.4179.721.2-30.5000111.1A664 F665P659-A664 HydrophobicContact CB-CB 3.87Å; P659-F665 HydrophobicContact CB-CB 4.17Å; P659-F665 HydrophobicContact CG-CB 3.97Å; P659-F665 HydrophobicContact CG-CD2 3.92Å; P659-F665 HydrophobicContact CG-CG 4.46Å
660Q84Confident80.2Confident178 Ų17895.3 Ų95.383%0.83249%0.494SS*.SBendtrans-93.8-5.6-175.8-59.4-62.7-36.900113.4R658R658-Q660 PolarHBondContact O-N 3.29Å; R658-Q660 PolarHBondContact O-NE2 2.03Å; R658-Q660 VanDerWaalsContact O-NE2 3.07Å
661S86.6Confident79.8Confident64 Ų6495.5 Ų95.545%0.44849%0.493SS..SBendtrans-135.7154178.275.50000111.1Q663 A664 F665S661-Q663 VanDerWaalsContact C-N 3.26Å; S661-Q663 PolarHBondContact O-N 2.96Å; S661-A664 PolarHBondContact O-N 3.19Å; S661-A664 VanDerWaalsContact OG-CB 3.29Å; S661-A664 WeakPolarHBondContact OG-CB 3.11Å; S661-A664 PolarHBondContact OG-N 3.42Å; S661-A664 VanDerWaalsContact OG-N 3.14Å; S661-F665 PolarHBondContact O-N 3.03Å
662L85.7Confident79.6Confident125 Ų125102.7 Ų102.765%0.65452%0.519SS*.Hα-helixtrans-61.3-36.8178.5-17270.9000111.8F665 H666L662-F665 PolarHBondContact O-N 2.94Å; L662-H666 PolarHBondContact O-N 3.18Å
663Q84.2Confident79.8Confident168 Ų168103.4 Ų103.479%0.78553%0.526SS*.Hα-helixtrans-67.9-40.3177.6-166.5170.14.600112S661 F665 H666 S667S661-Q663 VanDerWaalsContact C-N 3.26Å; S661-Q663 PolarHBondContact O-N 2.96Å; Q663-F665 VanDerWaalsContact C-N 3.34Å; Q663-H666 PolarHBondContact O-N 2.68Å; Q663-S667 PolarHBondContact O-N 3.13Å
664A82.1Confident80.3Confident36 Ų36107.1 Ų107.130%0.29854%0.536SS..Hα-helixtrans-63.6-41.4172.600000111.3P659 S661 S667 V668P659-A664 HydrophobicContact CB-CB 3.87Å; S661-A664 PolarHBondContact O-N 3.19Å; S661-A664 VanDerWaalsContact OG-CB 3.29Å; S661-A664 WeakPolarHBondContact OG-CB 3.11Å; S661-A664 PolarHBondContact OG-N 3.42Å; S661-A664 VanDerWaalsContact OG-N 3.14Å; A664-S667 PolarHBondContact O-N 2.74Å; A664-V668 WeakPolarHBondContact O-CG2 3.28Å; A664-V668 PolarHBondContact O-N 3.41Å
665F84.4Confident80.8Confident104 Ų104106.7 Ų106.746%0.45653%0.528SS..Hα-helixtrans-60.4-46.1175.5176.6-98.7000112.2P659 S661 L662 Q663 S667 V668 Y669P659-F665 HydrophobicContact CB-CB 4.17Å; P659-F665 HydrophobicContact CG-CB 3.97Å; P659-F665 HydrophobicContact CG-CD2 3.92Å; P659-F665 HydrophobicContact CG-CG 4.46Å; S661-F665 PolarHBondContact O-N 3.03Å; L662-F665 PolarHBondContact O-N 2.94Å; Q663-F665 VanDerWaalsContact C-N 3.34Å; F665-S667 VanDerWaalsContact C-N 3.32Å; F665-S667 PolarHBondContact O-N 3.46Å; F665-V668 PolarHBondContact O-N 3.4Å; F665-Y669 VanDerWaalsContact O-CB 3.29Å; F665-Y669 WeakPolarHBondContact O-CB 3.4Å; F665-Y669 PolarHBondContact O-N 3.28Å
666H84.5Confident81.6Confident100 Ų100106.8 Ų106.846%0.46352%0.519SS..Hα-helixtrans-61.5-39.4176-73.3177.7000112.7L662 Q663 Y669 Q670L662-H666 PolarHBondContact O-N 3.18Å; Q663-H666 PolarHBondContact O-N 2.68Å; H666-Y669 PolarHBondContact O-N 3.33Å; H666-Q670 WeakPolarHBondContact O-CB 3.23Å; H666-Q670 VanDerWaalsContact O-CG 3.31Å; H666-Q670 WeakPolarHBondContact O-CG 3.37Å; H666-Q670 PolarHBondContact O-N 3.35Å
667S82Confident82.6Confident70 Ų70108.1 Ų108.149%0.4952%0.517SS..Hα-helixtrans-62.4-49.9176.6-169.90000111.7Q663 A664 F665 Y669 Q670 E671Q663-S667 PolarHBondContact O-N 3.13Å; A664-S667 PolarHBondContact O-N 2.74Å; F665-S667 VanDerWaalsContact C-N 3.32Å; F665-S667 PolarHBondContact O-N 3.46Å; S667-Y669 VanDerWaalsContact C-N 3.31Å; S667-Y669 PolarHBondContact O-N 3Å; S667-Q670 PolarHBondContact O-N 3.37Å; S667-E671 PolarHBondContact O-N 2.93Å
668V81.3Confident83.2Confident72 Ų72108.2 Ų108.244%0.43651%0.514SS..Hα-helixtrans-61.7-40.9177.5173.80000110.8A664 F665 E671 W672A664-V668 WeakPolarHBondContact O-CG2 3.28Å; A664-V668 PolarHBondContact O-N 3.41Å; F665-V668 PolarHBondContact O-N 3.4Å; V668-E671 PolarHBondContact O-N 3.03Å; V668-W672 WeakPolarHBondContact O-CB 3.4Å; V668-W672 PolarHBondContact O-N 3.18Å
669Y84Confident83.7Confident139 Ų139104 Ų10455%0.54550%0.499SS..Hα-helixtrans-64-43.5177.7-175.9-96.1000112.5F665 H666 S667 E671 W672 C673F665-Y669 VanDerWaalsContact O-CB 3.29Å; F665-Y669 WeakPolarHBondContact O-CB 3.4Å; F665-Y669 PolarHBondContact O-N 3.28Å; H666-Y669 PolarHBondContact O-N 3.33Å; S667-Y669 VanDerWaalsContact C-N 3.31Å; S667-Y669 PolarHBondContact O-N 3Å; Y669-E671 VanDerWaalsContact C-N 3.35Å; Y669-E671 PolarHBondContact O-N 3.18Å; Y669-W672 PolarHBondContact O-N 2.03Å; Y669-C673 VanDerWaalsContact CE1-SG 3.54Å; Y669-C673 WeakPolarHBondContact O-CB 3.4Å; Y669-C673 PolarHBondContact O-N 2.64Å; Y669-C673 PolarHBondContact O-SG 3.49Å
670Q84.6Confident84Confident140 Ų140106.2 Ų106.265%0.65450%0.504SS*.Hα-helixtrans-62.4-41.8176.5-77.1177.8-3.400112.1H666 S667 C673 R674H666-Q670 WeakPolarHBondContact O-CB 3.23Å; H666-Q670 VanDerWaalsContact O-CG 3.31Å; H666-Q670 WeakPolarHBondContact O-CG 3.37Å; H666-Q670 PolarHBondContact O-N 3.35Å; S667-Q670 PolarHBondContact O-N 3.37Å; Q670-C673 PolarHBondContact O-N 3.09Å; Q670-R674 PolarHBondContact O-N 3.15Å
671E82Confident84.1Confident84 Ų84102.3 Ų102.339%0.39349%0.488SS..Hα-helixtrans-62.4-48174.5177.1149.8-126.100111.5S667 V668 Y669 C673 R674 E675S667-E671 PolarHBondContact O-N 2.93Å; V668-E671 PolarHBondContact O-N 3.03Å; Y669-E671 VanDerWaalsContact C-N 3.35Å; Y669-E671 PolarHBondContact O-N 3.18Å; E671-C673 VanDerWaalsContact C-N 3.3Å; E671-C673 PolarHBondContact O-N 3.28Å; E671-R674 WeakPolarHBondContact O-CA 3.17Å; E671-R674 WeakPolarHBondContact O-CB 3.38Å; E671-R674 PolarHBondContact O-N 3.39Å; E671-R674 IonicContact OE1-CZ 3.04Å; E671-R674 IonicContact OE1-NH2 3.29Å; E671-R674 PolarHBondContact OE1-NH2 3.34Å; E671-E675 HydrophobicContact CG-CG 4.49Å; E671-E675 WeakPolarHBondContact O-CG 3.25Å; E671-E675 PolarHBondContact O-N 3.18Å
672W82.6Confident83.8Confident176 Ų176103 Ų10367%0.66749%0.49SS*.Hα-helixtrans-61.4-38.7177.5-14684.4000112.3V668 Y669 R674 F676V668-W672 WeakPolarHBondContact O-CB 3.4Å; V668-W672 PolarHBondContact O-N 3.18Å; Y669-W672 PolarHBondContact O-N 2.03Å; W672-R674 VanDerWaalsContact C-N 3.35Å; W672-R674 PolarHBondContact O-N 3.32Å; W672-F676 HydrophobicContact CE3-CB 4.43Å; W672-F676 HydrophobicContact CZ3-CD2 4.44Å; W672-F676 HydrophobicContact CZ3-CG 4.49Å; W672-F676 WeakPolarHBondContact O-CB 3.32Å; W672-F676 PolarHBondContact O-N 3.1Å
673C86.8Confident83.6Confident49 Ų4999.5 Ų99.533%0.33147%0.471SS..Hα-helixtrans-60.8-41.9171.8-78.10000112.2Y669 Q670 E671 Q677Y669-C673 VanDerWaalsContact CE1-SG 3.54Å; Y669-C673 WeakPolarHBondContact O-CB 3.4Å; Y669-C673 PolarHBondContact O-N 2.64Å; Y669-C673 PolarHBondContact O-SG 3.49Å; Q670-C673 PolarHBondContact O-N 3.09Å; E671-C673 VanDerWaalsContact C-N 3.3Å; E671-C673 PolarHBondContact O-N 3.28Å; C673-Q677 VanDerWaalsContact O-CG 3.25Å; C673-Q677 WeakPolarHBondContact O-CG 3.21Å; C673-Q677 PolarHBondContact O-N 3.34Å; C673-Q677 VanDerWaalsContact O-N 3.07Å
674R84.8Confident83.7Confident123 Ų12396.8 Ų96.846%0.46446%0.461SS..Hα-helixtrans-63.4-51.9177.1-175.1-171.568.9-137.4-4.7111Q670 E671 W672 F676 Q677 E678Q670-R674 PolarHBondContact O-N 3.15Å; E671-R674 WeakPolarHBondContact O-CA 3.17Å; E671-R674 WeakPolarHBondContact O-CB 3.38Å; E671-R674 PolarHBondContact O-N 3.39Å; E671-R674 IonicContact OE1-CZ 3.04Å; E671-R674 IonicContact OE1-NH2 3.29Å; E671-R674 PolarHBondContact OE1-NH2 3.34Å; W672-R674 VanDerWaalsContact C-N 3.35Å; W672-R674 PolarHBondContact O-N 3.32Å; R674-F676 VanDerWaalsContact C-N 3.3Å; R674-F676 PolarHBondContact O-N 3.46Å; R674-Q677 WeakPolarHBondContact O-CB 3.49Å; R674-Q677 PolarHBondContact O-N 2.73Å; R674-Q677 VanDerWaalsContact O-N 3.12Å; R674-E678 PolarHBondContact O-N 3.01Å
675E82Confident83.5Confident91 Ų91103.3 Ų103.343%0.42548%0.478SS..Hα-helixtrans-59.2-41.1178.2-64-55.2132.800111.5E671 Q677 E678 Y679E671-E675 HydrophobicContact CG-CG 4.49Å; E671-E675 WeakPolarHBondContact O-CG 3.25Å; E671-E675 PolarHBondContact O-N 3.18Å; E675-Q677 VanDerWaalsContact C-N 3.33Å; E675-Q677 PolarHBondContact O-N 2.91Å; E675-E678 PolarHBondContact O-N 2.98Å; E675-Y679 WeakPolarHBondContact O-CB 3.4Å; E675-Y679 PolarHBondContact O-N 2.73Å
676F85.2Confident83.4Confident78 Ų78104.5 Ų104.534%0.34248%0.48SS..Hα-helixtrans-65.4-34.2177.1-174.4-119.1000113W672 R674 Y679 K680W672-F676 HydrophobicContact CE3-CB 4.43Å; W672-F676 HydrophobicContact CZ3-CD2 4.44Å; W672-F676 HydrophobicContact CZ3-CG 4.49Å; W672-F676 WeakPolarHBondContact O-CB 3.32Å; W672-F676 PolarHBondContact O-N 3.1Å; R674-F676 VanDerWaalsContact C-N 3.3Å; R674-F676 PolarHBondContact O-N 3.46Å; F676-Y679 HydrophobicContact CD2-CD1 4.48Å; F676-K680 HydrophobicContact CD1-CD 4.41Å; F676-K680 HydrophobicContact CE1-CD 4.19Å; F676-K680 VanDerWaalsContact CZ-CE 3.47Å; F676-K680 WeakPolarHBondContact O-CG 3.24Å; F676-K680 PolarHBondContact O-N 3.42Å
677Q86.4Confident83.3Confident110 Ų110103.7 Ų103.751%0.51448%0.475SS..Hα-helixtrans-69.1-41.1173.1-68.7-66.5-19.900111.5C673 R674 E675 K680 L681C673-Q677 VanDerWaalsContact O-CG 3.25Å; C673-Q677 WeakPolarHBondContact O-CG 3.21Å; C673-Q677 PolarHBondContact O-N 3.34Å; C673-Q677 VanDerWaalsContact O-N 3.07Å; R674-Q677 WeakPolarHBondContact O-CB 3.49Å; R674-Q677 PolarHBondContact O-N 2.73Å; R674-Q677 VanDerWaalsContact O-N 3.12Å; E675-Q677 VanDerWaalsContact C-N 3.33Å; E675-Q677 PolarHBondContact O-N 2.91Å; Q677-K680 PolarHBondContact O-N 3.28Å; Q677-L681 WeakPolarHBondContact O-CG 3.5Å; Q677-L681 PolarHBondContact O-N 2.99Å
678E81.7Confident83.2Confident108 Ų108106.8 Ų106.851%0.50548%0.479SS..Hα-helixtrans-63.6-40.6174-69.9-163.5176.800112.3R674 E675 L681 T682R674-E678 PolarHBondContact O-N 3.01Å; E675-E678 PolarHBondContact O-N 2.98Å; E678-L681 PolarHBondContact O-N 3.13Å; E678-T682 WeakPolarHBondContact O-CB 3.44Å; E678-T682 PolarHBondContact O-N 3.17Å; E678-T682 PolarHBondContact O-OG1 2.91Å
679Y84Confident83Confident127 Ų127110.2 Ų110.250%0.49849%0.485SS..Hα-helixtrans-57.9-48.5173174.6-100000111.2E675 F676 L681 T682 M683E675-Y679 WeakPolarHBondContact O-CB 3.4Å; E675-Y679 PolarHBondContact O-N 2.73Å; F676-Y679 HydrophobicContact CD2-CD1 4.48Å; Y679-L681 VanDerWaalsContact C-N 3.34Å; Y679-L681 PolarHBondContact O-N 2.63Å; Y679-T682 PolarHBondContact O-N 3.43Å; Y679-M683 HydrophobicContact CD1-CG 4.28Å; Y679-M683 HydrophobicContact CD2-CG 4.34Å; Y679-M683 HydrophobicContact CE1-CG 3.72Å; Y679-M683 HydrophobicContact CE2-CG 3.8Å; Y679-M683 VanDerWaalsContact CZ-CG 3.46Å; Y679-M683 WeakPolarHBondContact O-CB 3.22Å; Y679-M683 PolarHBondContact O-N 2.87Å
680K84.4Confident82.7Confident89 Ų89105 Ų10539%0.38746%0.464SS..Hα-helixtrans-56.9-45.5176-79.5175.8173.5174.10112.3F676 Q677 T682 M683 L684F676-K680 HydrophobicContact CD1-CD 4.41Å; F676-K680 HydrophobicContact CE1-CD 4.19Å; F676-K680 VanDerWaalsContact CZ-CE 3.47Å; F676-K680 WeakPolarHBondContact O-CG 3.24Å; F676-K680 PolarHBondContact O-N 3.42Å; Q677-K680 PolarHBondContact O-N 3.28Å; K680-T682 VanDerWaalsContact C-N 3.33Å; K680-T682 PolarHBondContact O-N 2.98Å; K680-M683 PolarHBondContact O-N 3.45Å; K680-L684 WeakPolarHBondContact O-CB 3.43Å; K680-L684 VanDerWaalsContact O-CG 3.28Å; K680-L684 WeakPolarHBondContact O-CG 3.42Å; K680-L684 PolarHBondContact O-N 3.3Å
681L86.1Confident82.4Confident95 Ų95102.3 Ų102.350%0.49745%0.454SS..Hα-helixtrans-63.9-39.6178-71.4171.8000112Q677 E678 Y679 L684 R685Q677-L681 WeakPolarHBondContact O-CG 3.5Å; Q677-L681 PolarHBondContact O-N 2.99Å; E678-L681 PolarHBondContact O-N 3.13Å; Y679-L681 VanDerWaalsContact C-N 3.34Å; Y679-L681 PolarHBondContact O-N 2.63Å; L681-L684 PolarHBondContact O-N 3.23Å; L681-R685 WeakPolarHBondContact O-CG 3.45Å; L681-R685 PolarHBondContact O-N 3.06Å
682T80.6Confident82Confident78 Ų78104.4 Ų104.448%0.47946%0.464SS..Hα-helixtrans-69.7-42.8179-56.90000111.3E678 Y679 K680 L684 R685 W686E678-T682 WeakPolarHBondContact O-CB 3.44Å; E678-T682 PolarHBondContact O-N 3.17Å; E678-T682 PolarHBondContact O-OG1 2.91Å; Y679-T682 PolarHBondContact O-N 3.43Å; K680-T682 VanDerWaalsContact C-N 3.33Å; K680-T682 PolarHBondContact O-N 2.98Å; T682-L684 VanDerWaalsContact C-N 3.33Å; T682-L684 PolarHBondContact O-N 3.41Å; T682-R685 PolarHBondContact O-N 3.48Å; T682-W686 WeakPolarHBondContact O-CB 3.23Å; T682-W686 PolarHBondContact O-N 3.04Å
683M81.8Confident81.6Confident53 Ų5398.8 Ų98.826%0.26145%0.447SS..Hα-helixtrans-60.3-41172.7-85.6-66.2-79.200112.2Y679 K680 W686 K687 E712Y679-M683 HydrophobicContact CD1-CG 4.28Å; Y679-M683 HydrophobicContact CD2-CG 4.34Å; Y679-M683 HydrophobicContact CE1-CG 3.72Å; Y679-M683 HydrophobicContact CE2-CG 3.8Å; Y679-M683 VanDerWaalsContact CZ-CG 3.46Å; Y679-M683 WeakPolarHBondContact O-CB 3.22Å; Y679-M683 PolarHBondContact O-N 2.87Å; K680-M683 PolarHBondContact O-N 3.45Å; M683-W686 PolarHBondContact O-N 3.02Å; M683-K687 VanDerWaalsContact O-CB 3.28Å; M683-K687 WeakPolarHBondContact O-CB 3.31Å; M683-K687 PolarHBondContact O-N 2.96Å; M683-E712 WeakPolarHBondContact CE-OE1 3.29Å
684L86.2Confident80.9Confident111 Ų11199.1 Ų99.158%0.58145%0.445SS*.Hα-helixtrans-63.7-41.2175-76.1168.3000112.2K680 L681 T682 K688K680-L684 WeakPolarHBondContact O-CB 3.43Å; K680-L684 VanDerWaalsContact O-CG 3.28Å; K680-L684 WeakPolarHBondContact O-CG 3.42Å; K680-L684 PolarHBondContact O-N 3.3Å; L681-L684 PolarHBondContact O-N 3.23Å; T682-L684 VanDerWaalsContact C-N 3.33Å; T682-L684 PolarHBondContact O-N 3.41Å; L684-K688 WeakPolarHBondContact O-CB 3.42Å; L684-K688 PolarHBondContact O-N 2.88Å
685R78.8Confident80Confident172 Ų172101.4 Ų101.465%0.64946%0.461SS*.Hα-helixtrans-64.3-45.3174.1-73.8-177.1-133.9163.34.8111.7L681 T682 K688 W689L681-R685 WeakPolarHBondContact O-CG 3.45Å; L681-R685 PolarHBondContact O-N 3.06Å; T682-R685 PolarHBondContact O-N 3.48Å; R685-K688 PolarHBondContact O-N 3.44Å; R685-W689 WeakPolarHBondContact O-CB 3.29Å; R685-W689 PolarHBondContact O-N 3.2Å
686W82.1Confident79.3Confident130 Ų130102.2 Ų102.249%0.49248%0.476SS..Hα-helixtrans-61.5-46.2177.7178.885000111.1T682 M683 K688 W689 Y690T682-W686 WeakPolarHBondContact O-CB 3.23Å; T682-W686 PolarHBondContact O-N 3.04Å; M683-W686 PolarHBondContact O-N 3.02Å; W686-K688 PolarHBondContact O-N 3.06Å; W686-W689 PolarHBondContact O-N 2.88Å; W686-Y690 HydrophobicContact CH2-CD2 4.3Å; W686-Y690 HydrophobicContact CH2-CG 4.38Å; W686-Y690 HydrophobicContact CZ2-CD2 4.27Å; W686-Y690 WeakPolarHBondContact O-CB 3.49Å; W686-Y690 PolarHBondContact O-N 3.09Å
687K81.1Confident77.9Confident82 Ų8299.8 Ų99.836%0.35747%0.468SS..Hα-helixtrans-57.5-47.7174.6176.1167.3-1791460111.7M683 W689 Y690 D691M683-K687 VanDerWaalsContact O-CB 3.28Å; M683-K687 WeakPolarHBondContact O-CB 3.31Å; M683-K687 PolarHBondContact O-N 2.96Å; K687-W689 VanDerWaalsContact C-N 3.35Å; K687-W689 PolarHBondContact O-N 2.94Å; K687-Y690 WeakPolarHBondContact O-CB 3.39Å; K687-Y690 PolarHBondContact O-N 2.61Å; K687-D691 WeakPolarHBondContact O-CB 3.13Å; K687-D691 VanDerWaalsContact O-CG 3.26Å; K687-D691 PolarHBondContact O-N 2.9Å
688K80.1Confident76.5Confident135 Ų135100.9 Ų100.959%0.58748%0.478SS*.Hα-helixtrans-59.8-44.9177-175.9-179.8-179.7-179.70112L684 R685 W686 Y690 Q692L684-K688 WeakPolarHBondContact O-CB 3.42Å; L684-K688 PolarHBondContact O-N 2.88Å; R685-K688 PolarHBondContact O-N 3.44Å; W686-K688 PolarHBondContact O-N 3.06Å; K688-Y690 VanDerWaalsContact C-N 3.34Å; K688-Q692 VanDerWaalsContact O-CG 3.26Å; K688-Q692 WeakPolarHBondContact O-CG 3.37Å; K688-Q692 PolarHBondContact O-N 2.95Å; K688-Q692 VanDerWaalsContact O-N 3.1Å
689W78.2Confident75.3Confident145 Ų145100.3 Ų100.355%0.54949%0.485SS..Hα-helixtrans-61.6-43.7175175.388.9000111.1R685 W686 K687 Q692 N693R685-W689 WeakPolarHBondContact O-CB 3.29Å; R685-W689 PolarHBondContact O-N 3.2Å; W686-W689 PolarHBondContact O-N 2.88Å; K687-W689 VanDerWaalsContact C-N 3.35Å; K687-W689 PolarHBondContact O-N 2.94Å; W689-Q692 WeakPolarHBondContact O-CB 3.13Å; W689-Q692 PolarHBondContact O-N 2.79Å; W689-N693 PolarHBondContact NE1-ND2 3.01Å; W689-N693 PolarHBondContact O-N 3.39Å; W689-N693 PolarHBondContact O-ND2 3.11Å
690Y76.9Confident73.9Confident30 Ų30101.3 Ų101.312%0.11849%0.493CS..Hα-helixtrans-62.3-47.9178176.9-94.1000111.8W686 K687 K688 Q692 N693 L694 L705W686-Y690 HydrophobicContact CH2-CD2 4.3Å; W686-Y690 HydrophobicContact CH2-CG 4.38Å; W686-Y690 HydrophobicContact CZ2-CD2 4.27Å; W686-Y690 WeakPolarHBondContact O-CB 3.49Å; W686-Y690 PolarHBondContact O-N 3.09Å; K687-Y690 WeakPolarHBondContact O-CB 3.39Å; K687-Y690 PolarHBondContact O-N 2.61Å; K688-Y690 VanDerWaalsContact C-N 3.34Å; Y690-Q692 PolarHBondContact O-N 2.7Å; Y690-N693 CarbonylContact O-C 3.56Å; Y690-N693 PolarHBondContact O-N 3.33Å; Y690-L694 HydrophobicContact CD1-CD1 4.1Å; Y690-L694 HydrophobicContact CE1-CD1 3.25Å; Y690-L694 HydrophobicContact CE2-CD1 4.32Å; Y690-L694 PolarHBondContact O-N 2.99Å; Y690-L694 VanDerWaalsContact OH-CD1 3.27Å; Y690-L694 WeakPolarHBondContact OH-CD1 3.47Å; Y690-L705 HydrophobicContact CE2-CD1 4.2Å; Y690-L705 WeakPolarHBondContact OH-CB 3.29Å; Y690-L705 WeakPolarHBondContact OH-CD1 3.38Å
691D77.7Confident72.5Confident83 Ų83101.1 Ų101.144%0.44450%0.496SS..Hα-helixtrans-59.7-36.5177.6-67.9-22.1000111.5K687 N693K687-D691 WeakPolarHBondContact O-CB 3.13Å; K687-D691 VanDerWaalsContact O-CG 3.26Å; K687-D691 PolarHBondContact O-N 2.9Å; D691-N693 VanDerWaalsContact C-N 3.34Å
692Q75.4Confident71Confident127 Ų127102 Ų10259%0.59349%0.492SS*.Hα-helixtrans-68.2-30.1174-73.7175-17.200113.3K688 W689 Y690K688-Q692 VanDerWaalsContact O-CG 3.26Å; K688-Q692 WeakPolarHBondContact O-CG 3.37Å; K688-Q692 PolarHBondContact O-N 2.95Å; K688-Q692 VanDerWaalsContact O-N 3.1Å; W689-Q692 WeakPolarHBondContact O-CB 3.13Å; W689-Q692 PolarHBondContact O-N 2.79Å; Y690-Q692 PolarHBondContact O-N 2.7Å
693N72.7Confident69.6Low58 Ų58108.1 Ų108.131%0.3151%0.507SS..Hα-helixtrans-103.51.4-176.2-69.7-81000113.6W689 Y690 D691 Q695 C696W689-N693 PolarHBondContact NE1-ND2 3.01Å; W689-N693 PolarHBondContact O-N 3.39Å; W689-N693 PolarHBondContact O-ND2 3.11Å; Y690-N693 CarbonylContact O-C 3.56Å; Y690-N693 PolarHBondContact O-N 3.33Å; D691-N693 VanDerWaalsContact C-N 3.34Å; N693-Q695 PolarHBondContact O-N 3.43Å; N693-C696 WeakPolarHBondContact O-CB 3.33Å; N693-C696 PolarHBondContact O-N 2.77Å
694L71.9Confident68.3Low57 Ų57112.4 Ų112.430%0.29852%0.524SS..G310 helixtrans-56.3-27.7178.9-160.382.5000112.5Y690 C696 S697 R702Y690-L694 HydrophobicContact CD1-CD1 4.1Å; Y690-L694 HydrophobicContact CE1-CD1 3.25Å; Y690-L694 HydrophobicContact CE2-CD1 4.32Å; Y690-L694 PolarHBondContact O-N 2.99Å; Y690-L694 VanDerWaalsContact OH-CD1 3.27Å; Y690-L694 WeakPolarHBondContact OH-CD1 3.47Å; L694-C696 VanDerWaalsContact C-N 3.25Å; L694-C696 PolarHBondContact O-N 3.17Å; L694-S697 PolarHBondContact O-N 3.15Å; L694-R702 PolarHBondContact O-NE 3.36Å; L694-R702 PolarHBondContact O-NH2 2.82Å
695Q67Low66.7Low170 Ų170110 Ų11079%0.79451%0.512SS*.G310 helixtrans-67.4-24.4176.4-61.8-175.55.800113.1N693 S697N693-Q695 PolarHBondContact O-N 3.43Å; Q695-S697 VanDerWaalsContact C-N 3.34Å
696C66.6Low65.7Low109 Ų109105 Ų10574%0.73650%0.503SS*.G310 helixtrans-85.3-5.4179.1-56.40000113.5N693 L694N693-C696 WeakPolarHBondContact O-CB 3.33Å; N693-C696 PolarHBondContact O-N 2.77Å; L694-C696 VanDerWaalsContact C-N 3.25Å; L694-C696 PolarHBondContact O-N 3.17Å
697S56.6Low64.3Low26 Ų26101 Ų10118%0.18250%0.498CS..SBendtrans-98.2133.8-177.7165.10000111.6L694 Q695 D701 R702L694-S697 PolarHBondContact O-N 3.15Å; Q695-S697 VanDerWaalsContact C-N 3.34Å; S697-D701 WeakPolarHBondContact OG-CB 3.46Å; S697-R702 PolarHBondContact O-NE 2.89Å
698D55.8Low63Low134 Ų13499.8 Ų99.872%0.71750%0.503SS*.  trans-61.9152.4176.9-103.8-28.5000112.4F700 D701D698-F700 PolarHBondContact O-N 3.24Å; D698-D701 PolarHBondContact O-N 2.82Å; D698-D701 VanDerWaalsContact O-N 3.08Å
699S57.9Low61.7Low95 Ų9597 Ų9766%0.66449%0.492SS*.Hα-helixtrans-55.8-26.9-17371.60000115
700F54.3Low60.4Low148 Ų14896.5 Ų96.565%0.64950%0.496SS*.Hα-helixtrans-73.1-38.1-179.5-164.7-98.5000112.6D698D698-F700 PolarHBondContact O-N 3.24Å
701D54.2Low59.1Low85 Ų85100.2 Ų100.246%0.45552%0.517SS..Hα-helixtrans-67.5-37.8177.5-85.3-23.8000111.4S697 D698 R703 K704 L705S697-D701 WeakPolarHBondContact OG-CB 3.46Å; D698-D701 PolarHBondContact O-N 2.82Å; D698-D701 VanDerWaalsContact O-N 3.08Å; D701-R703 VanDerWaalsContact C-N 3.27Å; D701-R703 PolarHBondContact O-N 2.9Å; D701-K704 PolarHBondContact O-N 3.45Å; D701-L705 HydrophobicContact CB-CD1 4.07Å; D701-L705 WeakPolarHBondContact O-CB 3.45Å; D701-L705 VanDerWaalsContact O-CD1 3.23Å; D701-L705 WeakPolarHBondContact O-CD1 3.49Å; D701-L705 VanDerWaalsContact O-CG 3.26Å; D701-L705 WeakPolarHBondContact O-CG 2.9Å; D701-L705 PolarHBondContact O-N 3.33Å; D701-L705 VanDerWaalsContact O-N 3.13Å
702R54.1Low57.8Low113 Ų113100.2 Ų100.243%0.42652%0.515SS..Hα-helixtrans-55.6-37.7179.5-66.6-174.2-176.3-179.53.7113.6L694 S697 S706L694-R702 PolarHBondContact O-NE 3.36Å; L694-R702 PolarHBondContact O-NH2 2.82Å; S697-R702 PolarHBondContact O-NE 2.89Å; R702-S706 PolarHBondContact O-N 3.13Å; R702-S706 VanDerWaalsContact O-N 3.14Å
703R52.2Low56.5Low208 Ų208103 Ų10379%0.78552%0.521SS*.Hα-helixtrans-76-41.5-177.1-71.1-174-173.9175.83113.4D701 L705 A707D701-R703 VanDerWaalsContact C-N 3.27Å; D701-R703 PolarHBondContact O-N 2.9Å; R703-L705 VanDerWaalsContact C-N 3.25Å; R703-L705 PolarHBondContact O-N 3.36Å; R703-A707 PolarHBondContact O-N 3.25Å
704K54.1Low55.3Low143 Ų143107.5 Ų107.562%0.62254%0.538SS*.Hα-helixtrans-65.2-34.4175.2-80.6-173176.5-178.50111.3D701 A708D701-K704 PolarHBondContact O-N 3.45Å; K704-A708 PolarHBondContact O-N 3.34Å
705L53.7Low54.3Low61 Ų61109.5 Ų109.532%0.31956%0.557SS.*Hα-helixtrans-77.6-33.1-176.8-69.5160.3000112.9Y690 D701 R703 A707 A708 Q709Y690-L705 HydrophobicContact CE2-CD1 4.2Å; Y690-L705 WeakPolarHBondContact OH-CB 3.29Å; Y690-L705 WeakPolarHBondContact OH-CD1 3.38Å; D701-L705 HydrophobicContact CB-CD1 4.07Å; D701-L705 WeakPolarHBondContact O-CB 3.45Å; D701-L705 VanDerWaalsContact O-CD1 3.23Å; D701-L705 WeakPolarHBondContact O-CD1 3.49Å; D701-L705 VanDerWaalsContact O-CG 3.26Å; D701-L705 WeakPolarHBondContact O-CG 2.9Å; D701-L705 PolarHBondContact O-N 3.33Å; D701-L705 VanDerWaalsContact O-N 3.13Å; R703-L705 VanDerWaalsContact C-N 3.25Å; R703-L705 PolarHBondContact O-N 3.36Å; L705-A707 VanDerWaalsContact C-N 3.31Å; L705-A707 PolarHBondContact O-N 2.92Å; L705-A708 PolarHBondContact O-N 3.33Å; L705-Q709 PolarHBondContact O-N 3.3Å
706S55.9Low53Low66 Ų66107 Ų10746%0.46255%0.549SS..Hα-helixtrans-65.2-37.1172.598.20000111.8R702 A708 Q709 E710R702-S706 PolarHBondContact O-N 3.13Å; R702-S706 VanDerWaalsContact O-N 3.14Å; S706-A708 VanDerWaalsContact C-N 3.34Å; S706-Q709 PolarHBondContact O-N 3.49Å; S706-E710 PolarHBondContact O-N 2.74Å
707A53Low51.7Low47 Ų47112.3 Ų112.339%0.38855%0.553SS.*Hα-helixtrans-66-36.1175.700000112.2R703 L705 N711R703-A707 PolarHBondContact O-N 3.25Å; L705-A707 VanDerWaalsContact C-N 3.31Å; L705-A707 PolarHBondContact O-N 2.92Å; A707-N711 PolarHBondContact O-N 3.1Å
708A54.2Low51Low56 Ų56118.8 Ų118.846%0.46359%0.585SS.*Hα-helixtrans-65.1-40.6172.800000111.9K704 L705 S706 N711 E712K704-A708 PolarHBondContact O-N 3.34Å; L705-A708 PolarHBondContact O-N 3.33Å; S706-A708 VanDerWaalsContact C-N 3.34Å; A708-N711 PolarHBondContact O-N 2.83Å; A708-E712 PolarHBondContact O-N 3.06Å
709Q52.7Low50.2Low76 Ų76118.3 Ų118.336%0.35559%0.587SS.*Hα-helixtrans-64.8-39.1176.8-78.7-177.5-2300113.5L705 S706 N711 E712 Y713L705-Q709 PolarHBondContact O-N 3.3Å; S706-Q709 PolarHBondContact O-N 3.49Å; Q709-N711 VanDerWaalsContact C-N 3.3Å; Q709-N711 PolarHBondContact O-N 3.25Å; Q709-E712 PolarHBondContact O-N 2.8Å; Q709-Y713 PolarHBondContact O-N 2.96Å
710E51.2Low48.9Very low134 Ų134121.9 Ų121.963%0.62659%0.593SS**Hα-helixtrans-63.8-35.7176-86.2-169.9162.100112.6S706S706-E710 PolarHBondContact O-N 2.74Å
711N50.4Low48.2Very low108 Ų108121.1 Ų121.158%0.57860%0.6SS**Hα-helixtrans-70.7-33.2176.8-75.1-23.2000112.1A707 A708 Q709 K714 S715A707-N711 PolarHBondContact O-N 3.1Å; A708-N711 PolarHBondContact O-N 2.83Å; Q709-N711 VanDerWaalsContact C-N 3.3Å; Q709-N711 PolarHBondContact O-N 3.25Å; N711-K714 PolarHBondContact O-N 3.22Å; N711-S715 PolarHBondContact O-N 2.98Å
712E50.5Low47.1Very low84 Ų84125.9 Ų125.939%0.39362%0.617SS.*Hα-helixtrans-73.3-36.3179.6-154.2179.9-173.200112.5M683 A708 Q709 K714 S715 N716M683-E712 WeakPolarHBondContact CE-OE1 3.29Å; A708-E712 PolarHBondContact O-N 3.06Å; Q709-E712 PolarHBondContact O-N 2.8Å; E712-K714 PolarHBondContact O-N 3.39Å; E712-S715 PolarHBondContact O-N 3.46Å; E712-S715 VanDerWaalsContact O-N 3.11Å; E712-N716 PolarHBondContact O-N 3.48Å
713Y47.4Very low46.2Very low185 Ų185127.6 Ų127.673%0.72567%0.67SS**Hα-helixtrans-60.6-30.9172-103.7-83.7000112.6Q709Q709-Y713 PolarHBondContact O-N 2.96Å
714K48Very low45.9Very low153 Ų153123.6 Ų123.667%0.66566%0.664SS**Hα-helixtrans-74.6-32.4175.1-70.9177.9-178.2171.20112.6N711 E712N711-K714 PolarHBondContact O-N 3.22Å; E712-K714 PolarHBondContact O-N 3.39Å
715S49.8Very low45.5Very low98 Ų98122.5 Ų122.569%0.68567%0.666SS**Hα-helixtrans-76.5-23.1-178.5-167.10000114N711 E712 R717N711-S715 PolarHBondContact O-N 2.98Å; E712-S715 PolarHBondContact O-N 3.46Å; E712-S715 VanDerWaalsContact O-N 3.11Å; S715-R717 VanDerWaalsContact C-N 3.31Å; S715-R717 PolarHBondContact O-N 3.14Å
716N39.7Very low45Very low119 Ų119125.9 Ų125.964%0.63669%0.685SS**THydrogen-bonded Turntrans-86.512.6-178.8-85.4-26.4000114.8E712 L718E712-N716 PolarHBondContact O-N 3.48Å; N716-L718 PolarHBondContact O-N 2.93Å
717R39.5Very low44.4Very low219 Ų219129.5 Ų129.583%0.82670%0.699SS**  trans-71.794.8165.6-81.3-172.2175.9-172.7-1109S715 V719S715-R717 VanDerWaalsContact C-N 3.31Å; S715-R717 PolarHBondContact O-N 3.14Å; R717-V719 PolarHBondContact O-N 3.27Å; R717-V719 VanDerWaalsContact O-N 3.15Å
718L41.8Very low43.8Very low163 Ų163134.6 Ų134.685%0.85372%0.718SS**  trans-47.1118.3165.3-78.8153.8000109.2N716 E720N716-L718 PolarHBondContact O-N 2.93Å; L718-E720 PolarHBondContact O-N 3.18Å
719V39.1Very low43.1Very low124 Ų124139.9 Ų139.975%0.75274%0.735SS**  trans-65.4110.8158.9175.70000105.2R717 V721R717-V719 PolarHBondContact O-N 3.27Å; R717-V719 VanDerWaalsContact O-N 3.15Å; V719-V721 PolarHBondContact O-N 3.05Å
720E32Very low42.5Very low170 Ų170144.4 Ų144.479%0.79476%0.762SS**  trans-55.8103.9164-95.2-174.6158.800107.5L718 K722L718-E720 PolarHBondContact O-N 3.18Å; E720-K722 VanDerWaalsContact C-N 3.32Å; E720-K722 PolarHBondContact O-N 3.07Å
721V37.7Very low41.8Very low132 Ų132145.2 Ų145.280%0.877%0.773SS**  trans-73.896.4165.6-176.20000105.4V719 G723V719-V721 PolarHBondContact O-N 3.05Å; V721-G723 PolarHBondContact O-N 2.69Å
722K32.7Very low41.1Very low184 Ų184148.3 Ų148.380%0.879%0.789SS**  trans-61.6120.3163.9-77.8-174.4175.5-179.60107E720E720-K722 VanDerWaalsContact C-N 3.32Å; E720-K722 PolarHBondContact O-N 3.07Å
723G34.7Very low40.2Very low149 Ų149154.2 Ų154.2100%1.53683%0.825SS**  trans-590-18000000113.4V721V721-G723 PolarHBondContact O-N 2.69Å

Retrieved 723 of 723 residues in 623.6 ms (Link to these results)