A0A077Z3Q2_TRITR Loading...

Deoxyribonuclease (DNase) II

AlphaFold DB , UniProt , Accession A0A077Z3Q2, Species TRITR (Trichuris trichiura, Whipworm), Gene n/a, Length 328 aa.

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Site Residue pLDDT pLDDT confidence pLDDT10 pLDDT10 confidence SASA SASA [Ų] SASA10 SASA10 [Ų] RSA RSA unformatted RSA10 RSA10 unformatted Surface Surface10 (not used) Disorder (not used) Disorder Sec. str. Secondary structure Isomer Phi (φ) Psi (ψ) Omega (ω) Chi 1 (χ1) Chi 2 (χ2) Chi 3 (χ3) Chi 4 (χ4) Chi 5 (χ5) Tau (τ) Contacts (colored by PAE) Contact details
1M78.9Confident63.7Low56 Ų5675.8 Ų75.828%0.27640%0.401SS..  0160.90-75.8150.9-6600108.6K67 A94 W95 E96 D99 V101M1-K67 HydrophobicContact SD-CD 4.19Å; M1-A94 HydrophobicContact SD-CB 4.15Å; M1-W95 VanDerWaalsContact CE-CA 3.44Å; M1-W95 HydrophobicContact CE-CB 4.35Å; M1-E96 HydrophobicContact CE-CB 4.47Å; M1-E96 HydrophobicContact CE-CG 4.1Å; M1-D99 WeakPolarHBondContact CE-O 3.31Å; M1-V101 HydrophobicContact CB-CB 4.32Å; M1-V101 HydrophobicContact CB-CG1 3.98Å; M1-V101 HydrophobicContact CG-CG1 4.37Å; M1-V101 HydrophobicContact SD-CG1 4.18Å
2V85.5Confident65.1Low30 Ų3071.6 Ų71.618%0.18238%0.38CS..  trans-138.4152.1-176.2-68.80000111G4 M11 T56V2-G4 WeakPolarHBondContact CG2-O 3.14Å; V2-M11 HydrophobicContact CG1-CE 4Å; V2-T56 WeakPolarHBondContact O-CB 3.5Å; V2-T56 WeakPolarHBondContact O-CG2 3.38Å; V2-T56 PolarHBondContact O-OG1 2.86Å; V2-T56 VanDerWaalsContact O-OG1 3.07Å
3C85.5Confident66.8Low0 Ų066.4 Ų66.40%035%0.353CS..SBendtrans-95.480.4164.4-80.60000108.8M30 V101 C134 I135 I136C3-M30 WeakPolarHBondContact O-CE 2.99Å; C3-V101 VanDerWaalsContact SG-CG2 3.56Å; C3-C134 WeakPolarHBondContact CA-SG 3.21Å; C3-C134 HydrophobicContact CB-CB 3.65Å; C3-C134 WeakPolarHBondContact CB-SG 3.36Å; C3-C134 VanDerWaalsContact SG-CA 3.6Å; C3-C134 WeakPolarHBondContact SG-CB 3.42Å; C3-C134 CovalentContact SG-SG 2.04Å; C3-C134 PolarHBondContact SG-SG 2.75Å; C3-I135 VanDerWaalsContact SG-CA 3.59Å; C3-I135 PolarHBondContact SG-N 2.83Å; C3-I136 HydrophobicContact CB-CD1 4.22Å; C3-I136 HydrophobicContact CB-CG1 4.17Å
4G69.6Low68.7Low1 Ų161.6 Ų61.61%0.0133%0.327CS..SBendtrans104.8-159.3177.300000116.6V2 P52 T56V2-G4 WeakPolarHBondContact CG2-O 3.14Å; G4-P52 WeakPolarHBondContact CA-O 3.06Å; G4-T56 PolarHBondContact N-OG1 2.98Å; G4-T56 VanDerWaalsContact N-OG1 3.1Å
5D61.8Low70.4Confident41 Ų4157.5 Ų57.522%0.21931%0.306CS..  trans-76.3143.7-161.8-166.87.3000114.1R7 P52 N55D5-R7 HydrophobicContact CB-CG 4.17Å; D5-R7 PolarHBondContact O-N 3.21Å; D5-R7 VanDerWaalsContact O-N 3.13Å; D5-R7 WeakPolarHBondContact OD2-CG 3.44Å; D5-P52 HydrophobicContact CB-CB 4.5Å; D5-N55 PolarHBondContact OD1-ND2 2.64Å
6I47.2Very low72.1Confident143 Ų14353.9 Ų53.973%0.73329%0.287SS*.  trans-83.859.6165.6-48.8169000107
7R51.2Low73.6Confident101 Ų10150.8 Ų50.838%0.38127%0.27SS..  trans-64.6158.2161-70.7-167.2-69.1-166.4-4.8108D5 F9 G10 E38D5-R7 HydrophobicContact CB-CG 4.17Å; D5-R7 PolarHBondContact O-N 3.21Å; D5-R7 VanDerWaalsContact O-N 3.13Å; D5-R7 WeakPolarHBondContact OD2-CG 3.44Å; R7-F9 HydrophobicContact CB-CD2 4.39Å; R7-F9 PolarHBondContact O-N 3.5Å; R7-G10 PolarHBondContact O-N 3.48Å; R7-E38 IonicContact CZ-OE1 2.87Å; R7-E38 IonicContact CZ-OE2 3.31Å; R7-E38 IonicContact NH1-OE1 3.68Å; R7-E38 IonicContact NH1-OE2 3.13Å; R7-E38 PolarHBondContact NH1-OE2 3.1Å; R7-E38 IonicContact NH2-OE1 3.39Å; R7-E38 PolarHBondContact NH2-OE1 2.89Å; R7-E38 IonicContact NH2-OE2 3.53Å
8P48.6Very low74.9Confident127 Ų12747.9 Ų47.983%0.82526%0.255SS*.THydrogen-bonded Turntrans-60.1-0.5-179.921.8-32.9000115.3
9F45.4Very low76.2Confident189 Ų18945.4 Ų45.483%0.82924%0.241SC*.THydrogen-bonded Turntrans-92.69.1-178.9-59.1-69.4000115R7R7-F9 HydrophobicContact CB-CD2 4.39Å; R7-F9 PolarHBondContact O-N 3.5Å
10G58.7Low77.3Confident44 Ų4443.8 Ų43.845%0.45423%0.232SC..  trans91-178.1168.900000114.8R7R7-G10 PolarHBondContact O-N 3.48Å
11M67.9Low78.2Confident102 Ų10243.5 Ų43.550%0.50223%0.233SC..  trans-68.9131.6-173.7-62.9-17872.400111.4V2 F198V2-M11 HydrophobicContact CG1-CE 4Å; M11-F198 HydrophobicContact CB-CD1 4.3Å; M11-F198 HydrophobicContact CB-CD2 3.69Å; M11-F198 HydrophobicContact CB-CE1 4.02Å; M11-F198 HydrophobicContact CB-CE2 3.4Å; M11-F198 VanDerWaalsContact CB-CE2 3.4Å; M11-F198 HydrophobicContact CB-CG 4.18Å; M11-F198 HydrophobicContact CB-CZ 3.61Å; M11-F198 HydrophobicContact CE-CE1 4.3Å; M11-F198 HydrophobicContact CE-CE2 3.73Å; M11-F198 HydrophobicContact CE-CZ 3.3Å; M11-F198 HydrophobicContact CG-CE1 4.42Å; M11-F198 HydrophobicContact CG-CE2 4.28Å; M11-F198 HydrophobicContact CG-CZ 4.05Å; M11-F198 HydrophobicContact SD-CE1 3.71Å; M11-F198 HydrophobicContact SD-CE2 4.04Å; M11-F198 HydrophobicContact SD-CZ 3.3Å; M11-F198 WeakPolarHBondContact SD-CZ 3.34Å
12V81.1Confident79.1Confident25 Ų2547.2 Ų47.215%0.15224%0.244CC..  trans-97.6127.9-179.5178.30000109.6W14 M30 A31V12-W14 WeakPolarHBondContact CG1-O 3.1Å; V12-M30 HydrophobicContact CB-CE 4.19Å; V12-M30 HydrophobicContact CG1-CB 4.37Å; V12-M30 HydrophobicContact CG1-CE 3.73Å; V12-M30 HydrophobicContact CG2-CE 4.2Å; V12-A31 HydrophobicContact CG1-CB 3.51Å
13D86.9Confident79.7Confident4 Ų447.6 Ų47.62%0.02125%0.247CC..SBendtrans-67.5-33.3178.4-82.5-30000114.4A31 I135 I136 S196 T197 F198 G199 F201D13-A31 HydrophobicContact CB-CB 4.26Å; D13-I135 CarbonylContact O-C 3.58Å; D13-I136 PolarHBondContact O-N 3.44Å; D13-S196 WeakPolarHBondContact OD2-CB 3.5Å; D13-S196 PolarHBondContact OD2-OG 3.33Å; D13-T197 PolarHBondContact OD1-N 3.39Å; D13-F198 WeakPolarHBondContact OD1-CB 3.32Å; D13-F198 WeakPolarHBondContact OD1-CD2 3.24Å; D13-F198 PolarHBondContact OD1-N 3.42Å; D13-G199 WeakPolarHBondContact OD2-CA 3.26Å; D13-G199 PolarHBondContact OD2-N 2.83Å; D13-F201 HydrophobicContact CB-CD2 4.15Å; D13-F201 HydrophobicContact CB-CE2 4.47Å; D13-F201 WeakPolarHBondContact OD2-CD2 3.47Å
14W93.3Very high80.3Confident0 Ų047.9 Ų47.90%025%0.249CC..EExtended strand (participates in β ladder)trans-158.3156-175.855.6-99.2000111.8V12 I16 I29 A31 P35 C134 I135 F201 I307 L312V12-W14 WeakPolarHBondContact CG1-O 3.1Å; W14-I16 HydrophobicContact CE3-CD1 4.16Å; W14-I16 HydrophobicContact CE3-CG1 4.2Å; W14-I16 HydrophobicContact CZ3-CD1 3.85Å; W14-I16 HydrophobicContact CZ3-CG1 4.25Å; W14-I29 HydrophobicContact CH2-CG2 4.13Å; W14-I29 HydrophobicContact CZ3-CG2 3.92Å; W14-A31 HydrophobicContact CD2-CB 3.65Å; W14-A31 VanDerWaalsContact CE2-CB 3.49Å; W14-A31 HydrophobicContact CE3-CB 4.28Å; W14-A31 HydrophobicContact CG-CB 3.84Å; W14-A31 HydrophobicContact CZ2-CB 4Å; W14-A31 WeakPolarHBondContact O-CB 3.37Å; W14-A31 PolarHBondContact O-N 3.29Å; W14-P35 HydrophobicContact CH2-CB 3.81Å; W14-P35 HydrophobicContact CH2-CG 4.12Å; W14-C134 CarbonylContact C-O 3.52Å; W14-C134 WeakPolarHBondContact CA-O 3.47Å; W14-C134 WeakPolarHBondContact CB-O 3.29Å; W14-I135 HydrophobicContact CB-CG1 4.24Å; W14-F201 AromaticContact CD1-CD2 3.79Å; W14-F201 AromaticContact NE1-CD2 3.27Å; W14-F201 VanDerWaalsContact NE1-CD2 3.27Å; W14-F201 AromaticContact NE1-CE2 3.6Å; W14-F201 AromaticContact NE1-CG 3.56Å; W14-I307 HydrophobicContact CB-CD1 4.22Å; W14-I307 HydrophobicContact CD2-CD1 3.59Å; W14-I307 HydrophobicContact CE3-CD1 3.91Å; W14-I307 HydrophobicContact CG-CD1 3.72Å; W14-I307 HydrophobicContact CZ2-CG2 4.42Å; W14-L312 HydrophobicContact CH2-CD1 4.38Å; W14-L312 HydrophobicContact CH2-CD2 3.88Å; W14-L312 HydrophobicContact CZ2-CD2 4.28Å; W14-L312 HydrophobicContact CZ3-CD2 4.29Å
15G94.6Very high81.6Confident0 Ų050.8 Ų50.80%026%0.264CS..EExtended strand (participates in β ladder)trans-140.1141.2173.700000110.6I29 M133 C134G15-I29 WeakPolarHBondContact CA-O 3.39Å; G15-M133 CarbonylContact O-C 3.59Å; G15-M133 WeakPolarHBondContact O-CA 3.43Å; G15-C134 PolarHBondContact N-O 3.03Å; G15-C134 PolarHBondContact O-N 3.15Å
16I96.9Very high83.3Confident0 Ų048.9 Ų48.90%025%0.254CS..EExtended strand (participates in β ladder)trans-116.9127.1175.1-63.8160.5000108W14 V28 I29 L131 I132 M133 F286 I307 L312 F316W14-I16 HydrophobicContact CE3-CD1 4.16Å; W14-I16 HydrophobicContact CE3-CG1 4.2Å; W14-I16 HydrophobicContact CZ3-CD1 3.85Å; W14-I16 HydrophobicContact CZ3-CG1 4.25Å; I16-V28 WeakPolarHBondContact O-CA 3.46Å; I16-I29 HydrophobicContact CB-CB 4.38Å; I16-I29 PolarHBondContact N-O 3.02Å; I16-I29 PolarHBondContact O-N 3.05Å; I16-L131 HydrophobicContact CG2-CD1 3.65Å; I16-I132 WeakPolarHBondContact CA-O 3.46Å; I16-M133 HydrophobicContact CD1-CE 3.92Å; I16-M133 HydrophobicContact CG1-CE 3.84Å; I16-M133 HydrophobicContact CG1-CG 4.46Å; I16-F286 HydrophobicContact CD1-CD1 3.73Å; I16-F286 HydrophobicContact CD1-CE1 3.44Å; I16-F286 VanDerWaalsContact CD1-CE1 3.44Å; I16-F286 HydrophobicContact CD1-CZ 4.49Å; I16-F286 HydrophobicContact CG1-CE1 4.25Å; I16-I307 HydrophobicContact CD1-CD1 4.41Å; I16-L312 HydrophobicContact CD1-CD1 3.79Å; I16-L312 HydrophobicContact CD1-CD2 3.82Å; I16-L312 HydrophobicContact CD1-CG 4.37Å; I16-F316 HydrophobicContact CG2-CZ 4.32Å
17F97.4Very high85.8Confident0 Ų042.3 Ų42.30%022%0.22CC..EExtended strand (participates in β ladder)trans-123.4110.4-179.3-39-90.6000108.5K19 A26 V28 M30 L44 P52 I132 C134F17-K19 PolarHBondContact O-N 3.32Å; F17-A26 HydrophobicContact CB-CB 4.21Å; F17-V28 HydrophobicContact CD1-CB 4.3Å; F17-V28 HydrophobicContact CD1-CG1 3.68Å; F17-V28 HydrophobicContact CD1-CG2 3.77Å; F17-V28 HydrophobicContact CE1-CG1 3.73Å; F17-M30 HydrophobicContact CE1-SD 4.13Å; F17-M30 HydrophobicContact CZ-SD 4.35Å; F17-L44 HydrophobicContact CB-CD1 3.93Å; F17-L44 HydrophobicContact CD1-CD2 4.07Å; F17-P52 HydrophobicContact CD1-CG 4.32Å; F17-P52 HydrophobicContact CE1-CB 4Å; F17-P52 HydrophobicContact CE1-CG 3.49Å; F17-P52 VanDerWaalsContact CE1-CG 3.49Å; F17-P52 HydrophobicContact CZ-CB 4.3Å; F17-P52 HydrophobicContact CZ-CG 4.26Å; F17-I132 HydrophobicContact CB-CB 4.14Å; F17-I132 HydrophobicContact CD2-CB 3.94Å; F17-I132 HydrophobicContact CD2-CG2 3.93Å; F17-I132 PolarHBondContact N-O 2.6Å; F17-I132 PolarHBondContact O-N 2.85Å; F17-C134 HydrophobicContact CE2-CB 4.11Å
18Y98.3Very high87.9Confident0 Ų037.5 Ų37.50%020%0.202CC..EExtended strand (participates in β ladder)trans-93.690.4174.6-148.3-50.1000108.3L20 A26 E27 A129 A130 L131 V261 I266 D271 S273 W275 F316Y18-L20 PolarHBondContact O-N 2.86Å; Y18-A26 VanDerWaalsContact O-CA 3.26Å; Y18-A26 WeakPolarHBondContact O-CA 3.41Å; Y18-E27 PolarHBondContact N-O 2.87Å; Y18-E27 PolarHBondContact O-N 2.97Å; Y18-A129 HydrophobicContact CE1-CB 4.27Å; Y18-A130 CarbonylContact C-O 3.59Å; Y18-L131 HydrophobicContact CD2-CD1 3.73Å; Y18-L131 HydrophobicContact CE2-CD1 4.33Å; Y18-L131 HydrophobicContact CG-CD1 4.01Å; Y18-V261 HydrophobicContact CD1-CG1 4.35Å; Y18-V261 HydrophobicContact CD1-CG2 4.14Å; Y18-V261 HydrophobicContact CD2-CG1 3.83Å; Y18-V261 HydrophobicContact CD2-CG2 3.81Å; Y18-V261 HydrophobicContact CE1-CG2 3.92Å; Y18-V261 HydrophobicContact CE2-CG1 4.44Å; Y18-V261 HydrophobicContact CE2-CG2 3.56Å; Y18-V261 HydrophobicContact CG-CG1 3.77Å; Y18-V261 HydrophobicContact CG-CG2 4.08Å; Y18-I266 HydrophobicContact CD1-CD1 4.19Å; Y18-I266 HydrophobicContact CE1-CD1 3.9Å; Y18-D271 PolarHBondContact OH-OD2 2.88Å; Y18-S273 PolarHBondContact OH-OG 3.38Å; Y18-W275 AromaticContact CE2-NE1 3.99Å; Y18-F316 HydrophobicContact CD2-CE1 4.19Å; Y18-F316 HydrophobicContact CD2-CZ 4.39Å; Y18-F316 HydrophobicContact CE2-CE1 4.13Å
19K98.3Very high90.1Very high0 Ų031.4 Ų31.40%016%0.162CC..EExtended strand (participates in β ladder)trans-60.3129.4175.7-178.7-152171.1-75.40109.1F17 T23 L107 F123 P124 A125 E127 K128 A129 A130F17-K19 PolarHBondContact O-N 3.32Å; K19-T23 WeakPolarHBondContact CE-O 3.43Å; K19-T23 PolarHBondContact NZ-O 3.19Å; K19-L107 HydrophobicContact CD-CD2 3.53Å; K19-F123 HydrophobicContact CD-CE1 3.99Å; K19-F123 HydrophobicContact CD-CZ 4.13Å; K19-F123 HydrophobicContact CG-CE1 4.14Å; K19-F123 HydrophobicContact CG-CZ 4.18Å; K19-P124 WeakPolarHBondContact CE-O 3.41Å; K19-A125 PolarHBondContact NZ-O 3.25Å; K19-A125 VanDerWaalsContact NZ-O 3.11Å; K19-E127 PolarHBondContact NZ-O 3.49Å; K19-K128 PolarHBondContact NZ-O 3.01Å; K19-K128 VanDerWaalsContact NZ-O 3.08Å; K19-A129 WeakPolarHBondContact O-CA 3.09Å; K19-A129 WeakPolarHBondContact O-CB 3.27Å; K19-A130 HydrophobicContact CB-CB 4.39Å; K19-A130 HydrophobicContact CD-CB 4.38Å; K19-A130 PolarHBondContact N-O 3.44Å; K19-A130 PolarHBondContact O-N 2.93Å; K19-A130 VanDerWaalsContact O-N 3.08Å
20L98.2Very high92.3Very high12 Ų1223.1 Ų23.16%0.06313%0.127CC..PPolyproline II helixtrans-78.4154.8177.2-59.8175.5000111.2Y18 T23 L25 E27 I264 I266Y18-L20 PolarHBondContact O-N 2.86Å; L20-T23 HydrophobicContact CB-CG2 3.43Å; L20-T23 VanDerWaalsContact CB-CG2 3.43Å; L20-L25 WeakPolarHBondContact CB-O 3.36Å; L20-L25 HydrophobicContact CD1-CB 4.07Å; L20-L25 PolarHBondContact N-O 2.96Å; L20-E27 HydrophobicContact CD2-CG 4.09Å; L20-I264 HydrophobicContact CD1-CD1 3.34Å; L20-I264 HydrophobicContact CD2-CB 4.34Å; L20-I264 HydrophobicContact CD2-CD1 3.81Å; L20-I264 HydrophobicContact CD2-CG2 4.15Å; L20-I264 HydrophobicContact CG-CD1 4.21Å; L20-I266 HydrophobicContact CD2-CD1 3.92Å
21P97.7Very high93.7Very high39 Ų3922.1 Ų22.125%0.25311%0.114SC..THydrogen-bonded Turntrans-69.5140.3-176.929-33.3000111.6T23 A129 I266 D270P21-T23 PolarHBondContact O-N 3.26Å; P21-A129 HydrophobicContact CB-CB 4.3Å; P21-I266 HydrophobicContact CG-CG2 4.49Å; P21-D270 HydrophobicContact CB-CB 4.22Å
22R97.7Very high94.3Very high133 Ų13321.4 Ų21.450%0.50211%0.112SC..THydrogen-bonded Turntrans57.925.5176.2-44.3-56.8172.9-141.6-12.2115.1A125 S126 E127 K128 D270R22-A125 CarbonylContact C-O 3.46Å; R22-A125 WeakPolarHBondContact CA-O 3.11Å; R22-S126 WeakPolarHBondContact CD-O 3.4Å; R22-S126 PolarHBondContact NH1-O 3.14Å; R22-E127 PolarHBondContact N-O 2.84Å; R22-K128 VanDerWaalsContact NH1-N 3.19Å; R22-D270 IonicContact CZ-OD1 3.31Å; R22-D270 IonicContact NH2-OD1 2.81Å; R22-D270 PolarHBondContact NH2-OD1 3.17Å
23T97.4Very high94.2Very high38 Ų3825.1 Ų25.123%0.23314%0.135CC..SBendtrans-146.7162.8175.4176.70000110.8K19 L20 P21 L25 A125K19-T23 WeakPolarHBondContact CE-O 3.43Å; K19-T23 PolarHBondContact NZ-O 3.19Å; L20-T23 HydrophobicContact CB-CG2 3.43Å; L20-T23 VanDerWaalsContact CB-CG2 3.43Å; P21-T23 PolarHBondContact O-N 3.26Å; T23-L25 VanDerWaalsContact C-N 3.32Å; T23-L25 HydrophobicContact CG2-CB 3.95Å; T23-L25 WeakPolarHBondContact OG1-CG 3.36Å; T23-L25 PolarHBondContact OG1-N 3Å; T23-A125 CarbonylContact C-O 3.56Å; T23-A125 PolarHBondContact N-O 2.78Å; T23-A125 VanDerWaalsContact O-O 3.1Å
24A97.6Very high94.3Very high6 Ų629.6 Ų29.65%0.0516%0.159CC..SBendtrans-84.1-8.2168.400000113.3D43 L44 S45 F123 A125A24-D43 WeakPolarHBondContact CB-OD1 3.39Å; A24-L44 PolarHBondContact O-N 2.77Å; A24-S45 WeakPolarHBondContact CB-OG 3.4Å; A24-F123 HydrophobicContact CB-CD1 3.88Å; A24-F123 HydrophobicContact CB-CE1 4.13Å; A24-A125 HydrophobicContact CB-CB 3.91Å
25L97.9Very high94.2Very high63 Ų6330 Ų3033%0.3316%0.161SC..EExtended strand (participates in β ladder)trans-66.5141.7177.7-63.6173.7000112L20 T23 P41 I42 D43L20-L25 WeakPolarHBondContact CB-O 3.36Å; L20-L25 HydrophobicContact CD1-CB 4.07Å; L20-L25 PolarHBondContact N-O 2.96Å; T23-L25 VanDerWaalsContact C-N 3.32Å; T23-L25 HydrophobicContact CG2-CB 3.95Å; T23-L25 WeakPolarHBondContact OG1-CG 3.36Å; T23-L25 PolarHBondContact OG1-N 3Å; L25-P41 HydrophobicContact CB-CB 4.29Å; L25-P41 HydrophobicContact CD2-CB 4.47Å; L25-I42 CarbonylContact C-O 3.58Å; L25-I42 WeakPolarHBondContact CA-O 3.38Å; L25-D43 HydrophobicContact CD2-CB 3.95Å
26A98Very high94.2Very high0 Ų034.5 Ų34.50%019%0.189CC..EExtended strand (participates in β ladder)trans-133.1142.7173.300000112.1F17 Y18 V28 P41 I42 L44F17-A26 HydrophobicContact CB-CB 4.21Å; Y18-A26 VanDerWaalsContact O-CA 3.26Å; Y18-A26 WeakPolarHBondContact O-CA 3.41Å; A26-V28 HydrophobicContact CB-CG2 4.27Å; A26-P41 CarbonylContact O-C 3.49Å; A26-P41 VanDerWaalsContact O-CA 3.24Å; A26-P41 WeakPolarHBondContact O-CA 3.29Å; A26-I42 PolarHBondContact N-O 2.9Å; A26-I42 PolarHBondContact O-N 2.89Å; A26-L44 HydrophobicContact CB-CD1 3.45Å; A26-L44 VanDerWaalsContact CB-CD1 3.45Å; A26-L44 HydrophobicContact CB-CD2 4.28Å; A26-L44 HydrophobicContact CB-CG 3.72Å
27E97.7Very high94.2Very high5 Ų535.7 Ų35.72%0.02319%0.193CC..EExtended strand (participates in β ladder)trans-78.1123.9163.2-67.1-74.4-179.900107.9Y18 L20 W37 V261 N262 I264Y18-E27 PolarHBondContact N-O 2.87Å; Y18-E27 PolarHBondContact O-N 2.97Å; L20-E27 HydrophobicContact CD2-CG 4.09Å; E27-W37 HydrophobicContact CB-CE3 3.71Å; E27-W37 HydrophobicContact CB-CZ3 3.67Å; E27-V261 HydrophobicContact CB-CG1 3.86Å; E27-V261 HydrophobicContact CG-CG1 4Å; E27-N262 HydrophobicContact CG-CB 4.15Å; E27-N262 PolarHBondContact OE1-ND2 3.03Å; E27-N262 WeakPolarHBondContact OE2-CB 3.15Å; E27-N262 PolarHBondContact OE2-ND2 3.31Å; E27-I264 WeakPolarHBondContact OE1-CD1 3.39Å
28V95.8Very high94Very high0 Ų037.8 Ų37.80%020%0.203CC..EExtended strand (participates in β ladder)trans-115.6139.8-167.5-178.40000111I16 F17 A26 M30 W37 E38 I42I16-V28 WeakPolarHBondContact O-CA 3.46Å; F17-V28 HydrophobicContact CD1-CB 4.3Å; F17-V28 HydrophobicContact CD1-CG1 3.68Å; F17-V28 HydrophobicContact CD1-CG2 3.77Å; F17-V28 HydrophobicContact CE1-CG1 3.73Å; A26-V28 HydrophobicContact CB-CG2 4.27Å; V28-M30 HydrophobicContact CG1-CG 4.11Å; V28-M30 HydrophobicContact CG1-SD 3.72Å; V28-W37 CarbonylContact O-C 3.54Å; V28-W37 WeakPolarHBondContact O-CA 3.33Å; V28-E38 HydrophobicContact CB-CB 4.42Å; V28-E38 HydrophobicContact CB-CG 4Å; V28-E38 HydrophobicContact CG1-CG 4.12Å; V28-E38 PolarHBondContact O-N 3.4Å; V28-I42 HydrophobicContact CB-CD1 4.24Å; V28-I42 HydrophobicContact CG1-CD1 4.4Å; V28-I42 HydrophobicContact CG2-CB 4.04Å; V28-I42 HydrophobicContact CG2-CD1 3.94Å; V28-I42 HydrophobicContact CG2-CG1 4.04Å
29I94.8Very high93.7Very high0 Ų042.3 Ų42.30%024%0.241CC..EExtended strand (participates in β ladder)trans-126.9126.8169.2-56.3156.5000107.2W14 G15 I16 P35 W37 L312 L315 F316W14-I29 HydrophobicContact CH2-CG2 4.13Å; W14-I29 HydrophobicContact CZ3-CG2 3.92Å; G15-I29 WeakPolarHBondContact CA-O 3.39Å; I16-I29 HydrophobicContact CB-CB 4.38Å; I16-I29 PolarHBondContact N-O 3.02Å; I16-I29 PolarHBondContact O-N 3.05Å; I29-P35 HydrophobicContact CG2-CB 3.61Å; I29-W37 HydrophobicContact CD1-CD2 4.22Å; I29-W37 HydrophobicContact CD1-CE3 3.79Å; I29-W37 HydrophobicContact CD1-CH2 3.6Å; I29-W37 HydrophobicContact CD1-CZ2 4.05Å; I29-W37 HydrophobicContact CD1-CZ3 3.47Å; I29-W37 VanDerWaalsContact CD1-CZ3 3.47Å; I29-W37 HydrophobicContact CG1-CD2 3.98Å; I29-W37 HydrophobicContact CG1-CE3 3.45Å; I29-W37 VanDerWaalsContact CG1-CE3 3.45Å; I29-W37 HydrophobicContact CG1-CH2 4.23Å; I29-W37 HydrophobicContact CG1-CZ3 3.61Å; I29-L312 HydrophobicContact CD1-CD1 4.01Å; I29-L312 HydrophobicContact CG2-CD1 4.26Å; I29-L315 HydrophobicContact CD1-CD2 3.43Å; I29-L315 VanDerWaalsContact CD1-CD2 3.43Å; I29-L315 HydrophobicContact CG1-CD2 3.83Å; I29-F316 HydrophobicContact CD1-CE2 3.8Å; I29-F316 HydrophobicContact CD1-CZ 4.45Å
30M91.9Very high93.5Very high15 Ų1548.5 Ų48.57%0.07427%0.273CS..EExtended strand (participates in β ladder)trans-105.7154174.8-59.6-55.7-69.900110.5C3 V12 F17 V28 N32 P52C3-M30 WeakPolarHBondContact O-CE 2.99Å; V12-M30 HydrophobicContact CB-CE 4.19Å; V12-M30 HydrophobicContact CG1-CB 4.37Å; V12-M30 HydrophobicContact CG1-CE 3.73Å; V12-M30 HydrophobicContact CG2-CE 4.2Å; F17-M30 HydrophobicContact CE1-SD 4.13Å; F17-M30 HydrophobicContact CZ-SD 4.35Å; V28-M30 HydrophobicContact CG1-CG 4.11Å; V28-M30 HydrophobicContact CG1-SD 3.72Å; M30-N32 PolarHBondContact O-N 3.03Å; M30-P52 HydrophobicContact CE-CB 4.37Å
31A87.8Confident93.3Very high22 Ų2250.1 Ų50.118%0.18228%0.284CS..  trans-57.2126.517800000112V12 D13 W14 F201V12-A31 HydrophobicContact CG1-CB 3.51Å; D13-A31 HydrophobicContact CB-CB 4.26Å; W14-A31 HydrophobicContact CD2-CB 3.65Å; W14-A31 VanDerWaalsContact CE2-CB 3.49Å; W14-A31 HydrophobicContact CE3-CB 4.28Å; W14-A31 HydrophobicContact CG-CB 3.84Å; W14-A31 HydrophobicContact CZ2-CB 4Å; W14-A31 WeakPolarHBondContact O-CB 3.37Å; W14-A31 PolarHBondContact O-N 3.29Å; A31-F201 HydrophobicContact CB-CE2 4.12Å
32N81.8Confident93.2Very high88 Ų8850 Ų5047%0.47128%0.281SS..  trans-151.5163.7171.2-172.6-33.2000106.4M30 N34 P35 F201M30-N32 PolarHBondContact O-N 3.03Å; N32-N34 VanDerWaalsContact C-N 3.27Å; N32-N34 PolarHBondContact OD1-N 3.2Å; N32-P35 WeakPolarHBondContact O-CD 3.41Å; N32-F201 WeakPolarHBondContact O-CZ 3.47Å
33T77.8Confident93.2Very high102 Ų10245.5 Ų45.563%0.62627%0.267SS*.SBendtrans-57.1-44162.7-50.20000110.8P35 N309T33-P35 WeakPolarHBondContact O-CD 2.94Å; T33-N309 PolarHBondContact O-ND2 3.48Å
34N89Confident93.2Very high98 Ų9843.7 Ų43.752%0.52426%0.256SS..SBendtrans-113.872.6177.4-62.1-47.7000111.1N32 T36N32-N34 VanDerWaalsContact C-N 3.27Å; N32-N34 PolarHBondContact OD1-N 3.2Å; N34-T36 PolarHBondContact O-N 2.81Å
35P92.2Very high93.1Very high9 Ų944.5 Ų44.56%0.05826%0.261CS..  trans-63.8135.3-178.126.5-34.3000111.8W14 I29 N32 T33 N309 E311 L312W14-P35 HydrophobicContact CH2-CB 3.81Å; W14-P35 HydrophobicContact CH2-CG 4.12Å; I29-P35 HydrophobicContact CG2-CB 3.61Å; N32-P35 WeakPolarHBondContact O-CD 3.41Å; T33-P35 WeakPolarHBondContact O-CD 2.94Å; P35-N309 WeakPolarHBondContact CG-OD1 3.36Å; P35-E311 HydrophobicContact CG-CB 4.24Å; P35-L312 HydrophobicContact CG-CB 3.86Å
36T94.9Very high93Very high94 Ų9446.1 Ų46.158%0.57727%0.267SS*.  trans-133164.4173.8-179.80000109.1N34N34-T36 PolarHBondContact O-N 2.81Å
37W95.2Very high92.8Very high25 Ų2549.2 Ų49.210%0.09528%0.283CS..BIsolated β-bridgetrans-58137.3165.2-57.5109.4000110E27 V28 I29 V261 N262 L315 F316 V319E27-W37 HydrophobicContact CB-CE3 3.71Å; E27-W37 HydrophobicContact CB-CZ3 3.67Å; V28-W37 CarbonylContact O-C 3.54Å; V28-W37 WeakPolarHBondContact O-CA 3.33Å; I29-W37 HydrophobicContact CD1-CD2 4.22Å; I29-W37 HydrophobicContact CD1-CE3 3.79Å; I29-W37 HydrophobicContact CD1-CH2 3.6Å; I29-W37 HydrophobicContact CD1-CZ2 4.05Å; I29-W37 HydrophobicContact CD1-CZ3 3.47Å; I29-W37 VanDerWaalsContact CD1-CZ3 3.47Å; I29-W37 HydrophobicContact CG1-CD2 3.98Å; I29-W37 HydrophobicContact CG1-CE3 3.45Å; I29-W37 VanDerWaalsContact CG1-CE3 3.45Å; I29-W37 HydrophobicContact CG1-CH2 4.23Å; I29-W37 HydrophobicContact CG1-CZ3 3.61Å; W37-V261 HydrophobicContact CH2-CG1 3.61Å; W37-V261 HydrophobicContact CZ2-CG1 4.08Å; W37-V261 HydrophobicContact CZ3-CG1 4.03Å; W37-N262 HydrophobicContact CB-CB 4.45Å; W37-N262 HydrophobicContact CD2-CB 3.91Å; W37-N262 HydrophobicContact CG-CB 3.81Å; W37-L315 HydrophobicContact CD2-CD2 4.17Å; W37-L315 HydrophobicContact CG-CD2 4.36Å; W37-L315 HydrophobicContact CZ2-CD2 4.16Å; W37-L315 HydrophobicContact CZ2-CG 4.08Å; W37-L315 VanDerWaalsContact NE1-CD1 3.27Å; W37-F316 HydrophobicContact CH2-CZ 4.28Å; W37-V319 HydrophobicContact CZ2-CG2 3.76Å
38E93.2Very high92.5Very high44 Ų4451.5 Ų51.521%0.20630%0.298CS..  trans-57.8154.4166.2-67.6-68.515300110.2R7 V28 L40R7-E38 IonicContact CZ-OE1 2.87Å; R7-E38 IonicContact CZ-OE2 3.31Å; R7-E38 IonicContact NH1-OE1 3.68Å; R7-E38 IonicContact NH1-OE2 3.13Å; R7-E38 PolarHBondContact NH1-OE2 3.1Å; R7-E38 IonicContact NH2-OE1 3.39Å; R7-E38 PolarHBondContact NH2-OE1 2.89Å; R7-E38 IonicContact NH2-OE2 3.53Å; V28-E38 HydrophobicContact CB-CB 4.42Å; V28-E38 HydrophobicContact CB-CG 4Å; V28-E38 HydrophobicContact CG1-CG 4.12Å; V28-E38 PolarHBondContact O-N 3.4Å; E38-L40 VanDerWaalsContact C-N 3.26Å; E38-L40 PolarHBondContact O-N 3.18Å
39A92.2Very high92.2Very high95 Ų9556.6 Ų56.679%0.78533%0.325SS*.SBendtrans-63.8-31.2-171.200000113.7
40L93.8Very high92Very high130 Ų13061.1 Ų61.168%0.68135%0.353SS*.SBendtrans-132147178.8-64.9175.1000109.9E38E38-L40 VanDerWaalsContact C-N 3.26Å; E38-L40 PolarHBondContact O-N 3.18Å
41P95.9Very high92Very high47 Ų4760.4 Ų60.431%0.30535%0.349SS..  trans-57.3145.9167.1-22.733.5000111.4L25 A26L25-P41 HydrophobicContact CB-CB 4.29Å; L25-P41 HydrophobicContact CD2-CB 4.47Å; A26-P41 CarbonylContact O-C 3.49Å; A26-P41 VanDerWaalsContact O-CA 3.24Å; A26-P41 WeakPolarHBondContact O-CA 3.29Å
42I95.7Very high92.2Very high36 Ų3659.6 Ų59.619%0.18534%0.342CS..EExtended strand (participates in β ladder)trans-108.1134178.8-57.3-179.7000109.3L25 A26 V28 L44 P52L25-I42 CarbonylContact C-O 3.58Å; L25-I42 WeakPolarHBondContact CA-O 3.38Å; A26-I42 PolarHBondContact N-O 2.9Å; A26-I42 PolarHBondContact O-N 2.89Å; V28-I42 HydrophobicContact CB-CD1 4.24Å; V28-I42 HydrophobicContact CG1-CD1 4.4Å; V28-I42 HydrophobicContact CG2-CB 4.04Å; V28-I42 HydrophobicContact CG2-CD1 3.94Å; V28-I42 HydrophobicContact CG2-CG1 4.04Å; I42-L44 PolarHBondContact O-N 2.03Å; I42-P52 HydrophobicContact CD1-CG 4.25Å
43D96.7Very high92.8Very high39 Ų3955.4 Ų55.421%0.20932%0.32CS..EExtended strand (participates in β ladder)trans-75111.1170.4-165.5-45.8000110A24 L25 S45 E46 N51A24-D43 WeakPolarHBondContact CB-OD1 3.39Å; L25-D43 HydrophobicContact CD2-CB 3.95Å; D43-S45 PolarHBondContact O-N 2.78Å; D43-S45 WeakPolarHBondContact OD1-CA 3.49Å; D43-S45 WeakPolarHBondContact OD1-CB 3.31Å; D43-S45 PolarHBondContact OD1-N 3.38Å; D43-S45 PolarHBondContact OD1-OG 3.28Å; D43-E46 HydrophobicContact CB-CG 3.92Å; D43-N51 PolarHBondContact O-ND2 2.98Å
44L96.7Very high93.5Very high0 Ų052.2 Ų52.20%030%0.296CS..THydrogen-bonded Turntrans-78.9-5-177.1-62.9-177.1000113.8F17 A24 A26 I42 N51 L53 F118 F123 I132F17-L44 HydrophobicContact CB-CD1 3.93Å; F17-L44 HydrophobicContact CD1-CD2 4.07Å; A24-L44 PolarHBondContact O-N 2.77Å; A26-L44 HydrophobicContact CB-CD1 3.45Å; A26-L44 VanDerWaalsContact CB-CD1 3.45Å; A26-L44 HydrophobicContact CB-CD2 4.28Å; A26-L44 HydrophobicContact CB-CG 3.72Å; I42-L44 PolarHBondContact O-N 2.03Å; L44-N51 PolarHBondContact O-ND2 3.41Å; L44-L53 HydrophobicContact CB-CD2 4.26Å; L44-L53 HydrophobicContact CD1-CD2 4.11Å; L44-L53 HydrophobicContact CD2-CB 4.04Å; L44-L53 HydrophobicContact CD2-CD2 4.44Å; L44-F118 WeakPolarHBondContact O-CZ 3.49Å; L44-F123 HydrophobicContact CB-CD2 4.2Å; L44-F123 HydrophobicContact CB-CE1 4.11Å; L44-F123 HydrophobicContact CB-CE2 3.64Å; L44-F123 HydrophobicContact CB-CZ 3.6Å; L44-F123 HydrophobicContact CD1-CE2 4.08Å; L44-F123 HydrophobicContact CD1-CZ 3.77Å; L44-F123 HydrophobicContact CG-CZ 4.32Å; L44-I132 HydrophobicContact CD1-CD1 3.9Å
45S96.5Very high93.7Very high22 Ų2248.3 Ų48.315%0.15428%0.275CS..THydrogen-bonded Turntrans-92.8-21.5177.273.10000113.4A24 D43 F118 P120A24-S45 WeakPolarHBondContact CB-OG 3.4Å; D43-S45 PolarHBondContact O-N 2.78Å; D43-S45 WeakPolarHBondContact OD1-CA 3.49Å; D43-S45 WeakPolarHBondContact OD1-CB 3.31Å; D43-S45 PolarHBondContact OD1-N 3.38Å; D43-S45 PolarHBondContact OD1-OG 3.28Å; S45-F118 WeakPolarHBondContact O-CE1 3.2Å; S45-P120 WeakPolarHBondContact O-CA 3.34Å; S45-P120 WeakPolarHBondContact O-CB 3.46Å; S45-P120 WeakPolarHBondContact O-CG 3.27Å
46E94.9Very high93.8Very high98 Ų9848 Ų4846%0.45827%0.274SS..  trans-70.6136.1-175-69.1-172.6161.700112.8D43 V48 N51D43-E46 HydrophobicContact CB-CG 3.92Å; E46-V48 HydrophobicContact CB-CG1 4.31Å; E46-V48 HydrophobicContact CB-CG2 3.73Å; E46-V48 PolarHBondContact O-N 3Å; E46-N51 PolarHBondContact O-ND2 3.34Å
47D94.3Very high93.8Very high64 Ų6443.7 Ų43.734%0.34225%0.247SC..  trans-83.261.1171.6-171.421000110.9R54 K58 F118 P120D47-R54 IonicContact OD1-CZ 3.42Å; D47-R54 VanDerWaalsContact OD1-CZ 3.32Å; D47-R54 IonicContact OD1-NE 3.98Å; D47-R54 PolarHBondContact OD1-NE 3.1Å; D47-R54 IonicContact OD1-NH2 3.87Å; D47-R54 PolarHBondContact OD1-NH2 3.26Å; D47-K58 IonicContact OD1-NZ 3.32Å; D47-K58 PolarHBondContact OD1-NZ 3.05Å; D47-K58 IonicContact OD2-NZ 3.06Å; D47-K58 PolarHBondContact OD2-NZ 2.76Å; D47-F118 HydrophobicContact CB-CD1 4.12Å; D47-P120 HydrophobicContact CB-CG 4.24Å
48V92.3Very high93.8Very high54 Ų5444.4 Ų44.433%0.32725%0.25SS..SBendtrans-124.3149.3179.2-63.70000110.4E46 T50 N51E46-V48 HydrophobicContact CB-CG1 4.31Å; E46-V48 HydrophobicContact CB-CG2 3.73Å; E46-V48 PolarHBondContact O-N 3Å; V48-T50 VanDerWaalsContact CG2-OG1 3.31Å; V48-T50 WeakPolarHBondContact CG2-OG1 3.19Å; V48-T50 PolarHBondContact O-N 3.15Å; V48-N51 HydrophobicContact CG2-CB 4.12Å; V48-N51 WeakPolarHBondContact O-CB 3.45Å; V48-N51 PolarHBondContact O-N 2.83Å
49D89.6Confident93.9Very high106 Ų10645.2 Ų45.257%0.56726%0.26SS*.THydrogen-bonded Turntrans-67.6-18.1-177-65.9-32.8000112.9N51 R54 N55D49-N51 PolarHBondContact O-N 2.75Å; D49-R54 IonicContact OD1-CZ 3Å; D49-R54 IonicContact OD1-NH1 3.96Å; D49-R54 PolarHBondContact OD1-NH1 3.07Å; D49-R54 IonicContact OD1-NH2 2.79Å; D49-N55 PolarHBondContact O-ND2 2.77Å
50T88.9Confident94Very high96 Ų9640.7 Ų40.759%0.58922%0.222SC*.THydrogen-bonded Turntrans-74.5-6.5171.452.40000113.4V48 P52V48-T50 VanDerWaalsContact CG2-OG1 3.31Å; V48-T50 WeakPolarHBondContact CG2-OG1 3.19Å; V48-T50 PolarHBondContact O-N 3.15Å; T50-P52 WeakPolarHBondContact O-CD 3.19Å
51N92.5Very high94.2Very high0 Ų035 Ų350%019%0.192CC..  trans-90102.4174.4177.7-3.3000110D43 L44 E46 V48 D49 L53 R54 N55D43-N51 PolarHBondContact O-ND2 2.98Å; L44-N51 PolarHBondContact O-ND2 3.41Å; E46-N51 PolarHBondContact O-ND2 3.34Å; V48-N51 HydrophobicContact CG2-CB 4.12Å; V48-N51 WeakPolarHBondContact O-CB 3.45Å; V48-N51 PolarHBondContact O-N 2.83Å; D49-N51 PolarHBondContact O-N 2.75Å; N51-L53 VanDerWaalsContact C-N 3.29Å; N51-L53 PolarHBondContact O-N 3.41Å; N51-L53 PolarHBondContact OD1-N 3.06Å; N51-R54 HydrophobicContact CB-CB 3.82Å; N51-R54 WeakPolarHBondContact ND2-CB 3.37Å; N51-R54 WeakPolarHBondContact O-CB 3.22Å; N51-R54 PolarHBondContact O-N 3.18Å; N51-R54 PolarHBondContact OD1-N 3.27Å; N51-N55 PolarHBondContact O-N 3.37Å
52P92.1Very high94.2Very high4 Ų436 Ų363%0.02620%0.201CC..Hα-helixtrans-61.7-34.3-178.524-34.7000113.3G4 D5 F17 M30 I42 T50 N55 T56G4-P52 WeakPolarHBondContact CA-O 3.06Å; D5-P52 HydrophobicContact CB-CB 4.5Å; F17-P52 HydrophobicContact CD1-CG 4.32Å; F17-P52 HydrophobicContact CE1-CB 4Å; F17-P52 HydrophobicContact CE1-CG 3.49Å; F17-P52 VanDerWaalsContact CE1-CG 3.49Å; F17-P52 HydrophobicContact CZ-CB 4.3Å; F17-P52 HydrophobicContact CZ-CG 4.26Å; M30-P52 HydrophobicContact CE-CB 4.37Å; I42-P52 HydrophobicContact CD1-CG 4.25Å; T50-P52 WeakPolarHBondContact O-CD 3.19Å; P52-N55 PolarHBondContact O-N 2.96Å; P52-T56 PolarHBondContact O-N 2.84Å; P52-T56 VanDerWaalsContact O-N 3.09Å; P52-T56 PolarHBondContact O-OG1 2.03Å
53L93.6Very high94.2Very high0 Ų035.7 Ų35.70%020%0.204CC..Hα-helixtrans-70.3-39.4-179.6-172.961.8000110.8L44 N51 T56 L57 W110 F123 I132L44-L53 HydrophobicContact CB-CD2 4.26Å; L44-L53 HydrophobicContact CD1-CD2 4.11Å; L44-L53 HydrophobicContact CD2-CB 4.04Å; L44-L53 HydrophobicContact CD2-CD2 4.44Å; N51-L53 VanDerWaalsContact C-N 3.29Å; N51-L53 PolarHBondContact O-N 3.41Å; N51-L53 PolarHBondContact OD1-N 3.06Å; L53-T56 WeakPolarHBondContact O-CB 3.05Å; L53-T56 PolarHBondContact O-N 2.82Å; L53-L57 HydrophobicContact CG-CD1 4.36Å; L53-L57 WeakPolarHBondContact O-CG 3.21Å; L53-L57 PolarHBondContact O-N 3.33Å; L53-W110 HydrophobicContact CD1-CH2 4.09Å; L53-W110 HydrophobicContact CD1-CZ2 4.3Å; L53-W110 HydrophobicContact CD2-CH2 4.16Å; L53-W110 HydrophobicContact CD2-CZ2 3.76Å; L53-W110 HydrophobicContact CG-CH2 4.48Å; L53-W110 HydrophobicContact CG-CZ2 4.2Å; L53-F123 HydrophobicContact CD2-CE2 3.98Å; L53-I132 HydrophobicContact CD1-CG2 4.34Å; L53-I132 HydrophobicContact CD2-CD1 3.78Å
54R93.9Very high94.2Very high36 Ų3635.3 Ų35.314%0.13620%0.2CC..Hα-helixtrans-59.6-45.1170.3174.2-89.7-176.3-162.76.8111.7D47 D49 N51 T56 L57 K58 F118D47-R54 IonicContact OD1-CZ 3.42Å; D47-R54 VanDerWaalsContact OD1-CZ 3.32Å; D47-R54 IonicContact OD1-NE 3.98Å; D47-R54 PolarHBondContact OD1-NE 3.1Å; D47-R54 IonicContact OD1-NH2 3.87Å; D47-R54 PolarHBondContact OD1-NH2 3.26Å; D49-R54 IonicContact OD1-CZ 3Å; D49-R54 IonicContact OD1-NH1 3.96Å; D49-R54 PolarHBondContact OD1-NH1 3.07Å; D49-R54 IonicContact OD1-NH2 2.79Å; N51-R54 HydrophobicContact CB-CB 3.82Å; N51-R54 WeakPolarHBondContact ND2-CB 3.37Å; N51-R54 WeakPolarHBondContact O-CB 3.22Å; N51-R54 PolarHBondContact O-N 3.18Å; N51-R54 PolarHBondContact OD1-N 3.27Å; R54-T56 PolarHBondContact O-N 2.59Å; R54-L57 PolarHBondContact O-N 3.35Å; R54-L57 VanDerWaalsContact O-N 3.14Å; R54-K58 HydrophobicContact CG-CB 4.44Å; R54-K58 VanDerWaalsContact O-CB 3.27Å; R54-K58 WeakPolarHBondContact O-CB 3.13Å; R54-K58 PolarHBondContact O-N 3.29Å; R54-F118 HydrophobicContact CB-CD1 4.02Å; R54-F118 HydrophobicContact CB-CD2 4.11Å; R54-F118 HydrophobicContact CB-CE1 3.8Å; R54-F118 HydrophobicContact CB-CE2 3.9Å; R54-F118 HydrophobicContact CB-CG 4.17Å; R54-F118 HydrophobicContact CB-CZ 3.75Å; R54-F118 HydrophobicContact CG-CB 4.28Å; R54-F118 HydrophobicContact CG-CD1 3.52Å; R54-F118 HydrophobicContact CG-CD2 4.14Å; R54-F118 HydrophobicContact CG-CE1 3.78Å; R54-F118 HydrophobicContact CG-CE2 4.36Å; R54-F118 HydrophobicContact CG-CG 3.71Å; R54-F118 HydrophobicContact CG-CZ 4.2Å
55N93.1Very high94.2Very high16 Ų1639.2 Ų39.29%0.08622%0.221CC..Hα-helixtrans-63-25.8178.8-68.7-15.2000112.9D5 D49 N51 P52 P59D5-N55 PolarHBondContact OD1-ND2 2.64Å; D49-N55 PolarHBondContact O-ND2 2.77Å; N51-N55 PolarHBondContact O-N 3.37Å; P52-N55 PolarHBondContact O-N 2.96Å; N55-P59 WeakPolarHBondContact O-CD 3.34Å; N55-P59 WeakPolarHBondContact O-CG 3.41Å
56T93.9Very high94.2Very high3 Ų342.2 Ų42.22%0.01824%0.235CC..Hα-helixtrans-74.7-52.2171.4-53.70000111V2 G4 P52 L53 R54 I60 V101 V103V2-T56 WeakPolarHBondContact O-CB 3.5Å; V2-T56 WeakPolarHBondContact O-CG2 3.38Å; V2-T56 PolarHBondContact O-OG1 2.86Å; V2-T56 VanDerWaalsContact O-OG1 3.07Å; G4-T56 PolarHBondContact N-OG1 2.98Å; G4-T56 VanDerWaalsContact N-OG1 3.1Å; P52-T56 PolarHBondContact O-N 2.84Å; P52-T56 VanDerWaalsContact O-N 3.09Å; P52-T56 PolarHBondContact O-OG1 2.03Å; L53-T56 WeakPolarHBondContact O-CB 3.05Å; L53-T56 PolarHBondContact O-N 2.82Å; R54-T56 PolarHBondContact O-N 2.59Å; T56-I60 HydrophobicContact CG2-CD1 4.36Å; T56-I60 WeakPolarHBondContact O-CD1 3.37Å; T56-I60 WeakPolarHBondContact O-CG1 3.33Å; T56-V101 HydrophobicContact CG2-CG2 3.72Å; T56-V103 HydrophobicContact CG2-CG2 4.19Å
57L95.4Very high94.3Very high3 Ų338.1 Ų38.12%0.01622%0.216CC..Hα-helixtrans-78.5-41.8-169.8-70.4-173.4000114.4L53 R54 I60 L61 M92 W110 F118L53-L57 HydrophobicContact CG-CD1 4.36Å; L53-L57 WeakPolarHBondContact O-CG 3.21Å; L53-L57 PolarHBondContact O-N 3.33Å; R54-L57 PolarHBondContact O-N 3.35Å; R54-L57 VanDerWaalsContact O-N 3.14Å; L57-I60 WeakPolarHBondContact O-CA 3.42Å; L57-I60 WeakPolarHBondContact O-CB 3.36Å; L57-I60 PolarHBondContact O-N 2.88Å; L57-L61 HydrophobicContact CB-CD1 4.23Å; L57-L61 WeakPolarHBondContact O-CG 3.33Å; L57-L61 PolarHBondContact O-N 3.43Å; L57-M92 HydrophobicContact CD2-CE 3.3Å; L57-M92 HydrophobicContact CD2-SD 4.38Å; L57-W110 HydrophobicContact CD1-CH2 4.07Å; L57-W110 HydrophobicContact CD1-CZ2 3.34Å; L57-W110 HydrophobicContact CG-CZ2 4.39Å; L57-F118 HydrophobicContact CB-CD2 3.95Å; L57-F118 HydrophobicContact CB-CE2 4.48Å; L57-F118 HydrophobicContact CD1-CD2 4.13Å; L57-F118 HydrophobicContact CD1-CE2 4.02Å
58K95Very high94.5Very high39 Ų3935 Ų3517%0.1720%0.199CC..Hα-helixtrans-55.7-51.5-174.5175.9135.6170.9158.20112D47 R54 I60 L61 S62 D117 F118D47-K58 IonicContact OD1-NZ 3.32Å; D47-K58 PolarHBondContact OD1-NZ 3.05Å; D47-K58 IonicContact OD2-NZ 3.06Å; D47-K58 PolarHBondContact OD2-NZ 2.76Å; R54-K58 HydrophobicContact CG-CB 4.44Å; R54-K58 VanDerWaalsContact O-CB 3.27Å; R54-K58 WeakPolarHBondContact O-CB 3.13Å; R54-K58 PolarHBondContact O-N 3.29Å; K58-I60 PolarHBondContact O-N 2.79Å; K58-I60 VanDerWaalsContact O-N 3.14Å; K58-L61 PolarHBondContact O-N 3.05Å; K58-S62 WeakPolarHBondContact O-CB 3.39Å; K58-S62 PolarHBondContact O-N 2.87Å; K58-S62 PolarHBondContact O-OG 3.17Å; K58-D117 WeakPolarHBondContact CD-OD1 3.37Å; K58-D117 WeakPolarHBondContact CE-OD1 3.49Å; K58-D117 WeakPolarHBondContact CE-OD2 3.44Å; K58-D117 VanDerWaalsContact CG-OD1 3.29Å; K58-D117 WeakPolarHBondContact CG-OD1 3.17Å; K58-D117 IonicContact NZ-OD1 2.87Å; K58-D117 PolarHBondContact NZ-OD1 3.39Å; K58-D117 IonicContact NZ-OD2 2.85Å; K58-D117 PolarHBondContact NZ-OD2 2.85Å; K58-F118 HydrophobicContact CB-CB 3.87Å; K58-F118 HydrophobicContact CD-CB 3.97Å; K58-F118 HydrophobicContact CG-CB 4.41Å
59P93.9Very high94.7Very high62 Ų6232.5 Ų32.540%0.40318%0.184SC..Hα-helixtrans-61.3-26.6176.4-23.235000114.3N55 K67N55-P59 WeakPolarHBondContact O-CD 3.34Å; N55-P59 WeakPolarHBondContact O-CG 3.41Å; P59-K67 VanDerWaalsContact O-CE 3.28Å; P59-K67 WeakPolarHBondContact O-CE 2.95Å; P59-K67 PolarHBondContact O-NZ 2.88Å
60I95.7Very high95.2Very high0 Ų027.4 Ų27.40%016%0.157CC..Hα-helixtrans-74.2-49.9176.2-61.1165000109.9T56 L57 K58 A63 K64 K67 I69 M92 A94 V101T56-I60 HydrophobicContact CG2-CD1 4.36Å; T56-I60 WeakPolarHBondContact O-CD1 3.37Å; T56-I60 WeakPolarHBondContact O-CG1 3.33Å; L57-I60 WeakPolarHBondContact O-CA 3.42Å; L57-I60 WeakPolarHBondContact O-CB 3.36Å; L57-I60 PolarHBondContact O-N 2.88Å; K58-I60 PolarHBondContact O-N 2.79Å; K58-I60 VanDerWaalsContact O-N 3.14Å; I60-A63 PolarHBondContact O-N 3.01Å; I60-K64 WeakPolarHBondContact O-CG 3.4Å; I60-K64 PolarHBondContact O-N 3.01Å; I60-K67 HydrophobicContact CB-CD 4.24Å; I60-K67 HydrophobicContact CG1-CD 4.19Å; I60-K67 HydrophobicContact CG2-CD 4.25Å; I60-I69 HydrophobicContact CG2-CD1 3.8Å; I60-I69 HydrophobicContact CG2-CG1 4.17Å; I60-M92 HydrophobicContact CD1-CE 3.53Å; I60-M92 HydrophobicContact CG2-CE 4.24Å; I60-M92 HydrophobicContact CG2-SD 4.24Å; I60-A94 HydrophobicContact CB-CB 4.45Å; I60-A94 HydrophobicContact CD1-CB 3.68Å; I60-A94 HydrophobicContact CG1-CB 3.81Å; I60-A94 HydrophobicContact CG2-CB 3.76Å; I60-V101 HydrophobicContact CD1-CG1 3.65Å
61L96.6Very high95.6Very high10 Ų1022.9 Ų22.95%0.05213%0.129CC..Hα-helixtrans-67.1-39.8-176.4-66171.4000112.4L57 K58 A63 K64 M113 S116 D117L57-L61 HydrophobicContact CB-CD1 4.23Å; L57-L61 WeakPolarHBondContact O-CG 3.33Å; L57-L61 PolarHBondContact O-N 3.43Å; K58-L61 PolarHBondContact O-N 3.05Å; L61-A63 VanDerWaalsContact C-N 3.33Å; L61-A63 PolarHBondContact O-N 3.26Å; L61-K64 WeakPolarHBondContact O-CG 3.36Å; L61-K64 PolarHBondContact O-NZ 3.3Å; L61-M113 HydrophobicContact CD2-CE 4.14Å; L61-M113 HydrophobicContact CD2-SD 4.1Å; L61-S116 CarbonylContact C-O 3.47Å; L61-D117 WeakPolarHBondContact CD1-O 3.43Å
62S96.4Very high95.9Very high69 Ų6922.9 Ų22.948%0.48313%0.129SC..THydrogen-bonded Turntrans-76.3-16.2-178.3-46.50000114.4K58 S116 D117K58-S62 WeakPolarHBondContact O-CB 3.39Å; K58-S62 PolarHBondContact O-N 2.87Å; K58-S62 PolarHBondContact O-OG 3.17Å; S62-S116 VanDerWaalsContact CA-O 3.26Å; S62-S116 WeakPolarHBondContact CA-O 3.44Å; S62-S116 PolarHBondContact N-O 2.92Å; S62-D117 PolarHBondContact OG-OD1 3.16Å
63A95.8Very high96.2Very high29 Ų2922.9 Ų22.924%0.2413%0.129CC..THydrogen-bonded Turntrans-138.547-174.800000112.5I60 L61 D65 N66I60-A63 PolarHBondContact O-N 3.01Å; L61-A63 VanDerWaalsContact C-N 3.33Å; L61-A63 PolarHBondContact O-N 3.26Å; A63-D65 VanDerWaalsContact C-N 3.25Å; A63-D65 PolarHBondContact O-N 3.21Å; A63-N66 PolarHBondContact O-N 3.5Å; A63-N66 VanDerWaalsContact O-N 3.13Å
64K96.9Very high96.4Very high30 Ų3023.1 Ų23.113%0.1313%0.131CC..G310 helixtrans-61.7-30.9-179.9-58.7-169.6-169.372.30113.5I60 L61 N66 K67 I69 M113 A115 F158 K160I60-K64 WeakPolarHBondContact O-CG 3.4Å; I60-K64 PolarHBondContact O-N 3.01Å; L61-K64 WeakPolarHBondContact O-CG 3.36Å; L61-K64 PolarHBondContact O-NZ 3.3Å; K64-N66 PolarHBondContact O-N 3.38Å; K64-K67 PolarHBondContact O-N 2.96Å; K64-K67 VanDerWaalsContact O-N 3.16Å; K64-K67 VanDerWaalsContact O-O 3.08Å; K64-I69 HydrophobicContact CB-CD1 3.79Å; K64-I69 HydrophobicContact CD-CD1 4.27Å; K64-I69 HydrophobicContact CG-CD1 3.72Å; K64-M113 HydrophobicContact CD-CE 4.34Å; K64-M113 WeakPolarHBondContact CE-O 3.4Å; K64-A115 PolarHBondContact NZ-O 3.03Å; K64-F158 HydrophobicContact CD-CE1 4.34Å; K64-F158 HydrophobicContact CD-CZ 3.82Å; K64-K160 VanDerWaalsContact C-CE 3.48Å; K64-K160 HydrophobicContact CB-CD 4.01Å; K64-K160 VanDerWaalsContact O-CE 3.27Å; K64-K160 WeakPolarHBondContact O-CE 3.24Å
65D96.7Very high96.6Very high83 Ų8322.5 Ų22.544%0.44413%0.129SC..G310 helixtrans-63.6-20.5176.8-73.2-37.4000113.6A63 K160 N163A63-D65 VanDerWaalsContact C-N 3.25Å; A63-D65 PolarHBondContact O-N 3.21Å; D65-K160 VanDerWaalsContact CA-CE 3.46Å; D65-K160 WeakPolarHBondContact OD1-CE 3.5Å; D65-K160 IonicContact OD1-NZ 2.67Å; D65-K160 PolarHBondContact OD1-NZ 3.4Å; D65-N163 WeakPolarHBondContact O-CB 3.29Å; D65-N163 PolarHBondContact O-N 3.07Å
66N96.7Very high96.8Very high85 Ų8522.5 Ų22.546%0.45513%0.132SC..G310 helixtrans-99-0.2179.3-61.2-27.4000112.6A63 K64 E96 A162A63-N66 PolarHBondContact O-N 3.5Å; A63-N66 VanDerWaalsContact O-N 3.13Å; K64-N66 PolarHBondContact O-N 3.38Å; N66-E96 WeakPolarHBondContact O-CG 3.35Å; N66-A162 VanDerWaalsContact C-CB 3.44Å; N66-A162 WeakPolarHBondContact O-CB 3.43Å
67K96.8Very high96.9Very high11 Ų1124.1 Ų24.15%0.04814%0.142CC..SBendtrans-128.1140.1-169.4-68.5178.7176.370.40112.4M1 P59 I60 K64 I69 E96 A162M1-K67 HydrophobicContact SD-CD 4.19Å; P59-K67 VanDerWaalsContact O-CE 3.28Å; P59-K67 WeakPolarHBondContact O-CE 2.95Å; P59-K67 PolarHBondContact O-NZ 2.88Å; I60-K67 HydrophobicContact CB-CD 4.24Å; I60-K67 HydrophobicContact CG1-CD 4.19Å; I60-K67 HydrophobicContact CG2-CD 4.25Å; K64-K67 PolarHBondContact O-N 2.96Å; K64-K67 VanDerWaalsContact O-N 3.16Å; K64-K67 VanDerWaalsContact O-O 3.08Å; K67-I69 HydrophobicContact CB-CD1 3.93Å; K67-I69 HydrophobicContact CB-CG1 3.79Å; K67-E96 WeakPolarHBondContact CE-OE1 3.34Å; K67-E96 HydrophobicContact CG-CG 3.84Å; K67-E96 WeakPolarHBondContact CG-OE1 3.39Å; K67-E96 IonicContact NZ-OE1 2.93Å; K67-E96 PolarHBondContact NZ-OE1 2.85Å; K67-A162 PolarHBondContact O-N 3.21Å
68N97.8Very high96.8Very high0 Ų027.9 Ų27.90%018%0.181CC..EExtended strand (participates in β ladder)trans-79.1115.4165.2-62.9-64.6000107.7A94 W95 K160 D161 A162 S165 L167 L168N68-A94 CarbonylContact O-C 3.44Å; N68-A94 VanDerWaalsContact O-CA 3.23Å; N68-A94 WeakPolarHBondContact O-CA 3.21Å; N68-W95 HydrophobicContact CB-CD2 3.73Å; N68-W95 HydrophobicContact CB-CE3 4.08Å; N68-W95 HydrophobicContact CB-CG 4.25Å; N68-W95 HydrophobicContact CB-CH2 4.47Å; N68-W95 HydrophobicContact CB-CZ2 4.08Å; N68-W95 HydrophobicContact CB-CZ3 4.43Å; N68-W95 WeakPolarHBondContact CB-O 3.23Å; N68-W95 PolarHBondContact N-O 2.78Å; N68-W95 PolarHBondContact O-N 2.75Å; N68-K160 CarbonylContact C-O 3.49Å; N68-K160 WeakPolarHBondContact CA-O 3.47Å; N68-D161 PolarHBondContact OD1-OD1 3.12Å; N68-A162 PolarHBondContact OD1-N 3.43Å; N68-S165 PolarHBondContact ND2-O 3.24Å; N68-S165 PolarHBondContact OD1-O 3.27Å; N68-L167 PolarHBondContact OD1-N 3.46Å; N68-L168 HydrophobicContact CB-CD2 4.12Å; N68-L168 HydrophobicContact CB-CG 3.99Å
69I98.3Very high96.8Very high0 Ų027.4 Ų27.40%019%0.185CC..EExtended strand (participates in β ladder)trans-128.6135.1-173.6-58.3166000110.1I60 K64 K67 M92 L93 A94 M113 F158 W159 K160 L168I60-I69 HydrophobicContact CG2-CD1 3.8Å; I60-I69 HydrophobicContact CG2-CG1 4.17Å; K64-I69 HydrophobicContact CB-CD1 3.79Å; K64-I69 HydrophobicContact CD-CD1 4.27Å; K64-I69 HydrophobicContact CG-CD1 3.72Å; K67-I69 HydrophobicContact CB-CD1 3.93Å; K67-I69 HydrophobicContact CB-CG1 3.79Å; I69-M92 HydrophobicContact CG2-CG 4.28Å; I69-M92 HydrophobicContact CG2-SD 4.49Å; I69-L93 VanDerWaalsContact CA-O 3.29Å; I69-L93 WeakPolarHBondContact CA-O 3.04Å; I69-A94 HydrophobicContact CG1-CB 4.16Å; I69-M113 HydrophobicContact CD1-CE 4.48Å; I69-M113 HydrophobicContact CG2-CE 3.66Å; I69-F158 HydrophobicContact CB-CE1 4.11Å; I69-F158 HydrophobicContact CG2-CD1 3.96Å; I69-F158 HydrophobicContact CG2-CE1 3.83Å; I69-W159 CarbonylContact O-C 3.59Å; I69-W159 WeakPolarHBondContact O-CA 3.49Å; I69-K160 PolarHBondContact N-O 2.73Å; I69-K160 PolarHBondContact O-N 3.06Å; I69-L168 VanDerWaalsContact O-CD1 3.32Å; I69-L168 WeakPolarHBondContact O-CD1 3.45Å
70I98.5Very high96.8Very high0 Ų029.4 Ų29.40%020%0.2CC..EExtended strand (participates in β ladder)trans-129.1129.1163.7-62.8174.5000107.2Y72 M92 L93 V156 W159 L168 F174 L177 I178I70-Y72 HydrophobicContact CG2-CD1 4.18Å; I70-M92 CarbonylContact O-C 3.51Å; I70-M92 VanDerWaalsContact O-CA 3.25Å; I70-M92 WeakPolarHBondContact O-CA 3.18Å; I70-L93 PolarHBondContact N-O 3.27Å; I70-L93 PolarHBondContact O-N 3.24Å; I70-V156 HydrophobicContact CG2-CG1 4.01Å; I70-V156 HydrophobicContact CG2-CG2 3.97Å; I70-W159 HydrophobicContact CG1-CB 4.28Å; I70-L168 HydrophobicContact CD1-CD2 3.75Å; I70-L168 HydrophobicContact CG1-CD1 3.93Å; I70-L168 HydrophobicContact CG1-CD2 3.83Å; I70-F174 HydrophobicContact CD1-CD1 3.55Å; I70-F174 HydrophobicContact CD1-CE1 4.17Å; I70-F174 HydrophobicContact CD1-CG 4.37Å; I70-L177 HydrophobicContact CD1-CD2 4.07Å; I70-I178 HydrophobicContact CD1-CD1 4.02Å; I70-I178 HydrophobicContact CD1-CG1 3.91Å; I70-I178 HydrophobicContact CG1-CD1 4.26Å; I70-I178 HydrophobicContact CG1-CG1 4.24Å
71A98.7Very high96.8Very high0 Ų033.7 Ų33.70%023%0.227CC..EExtended strand (participates in β ladder)trans-123137.3167.400000110.2G91 M92 M113 Y157 F158A71-G91 WeakPolarHBondContact CA-O 2.99Å; A71-M92 HydrophobicContact CB-CB 4.28Å; A71-M92 HydrophobicContact CB-CG 4.13Å; A71-M113 HydrophobicContact CB-CG 3.71Å; A71-M113 HydrophobicContact CB-SD 4.18Å; A71-Y157 VanDerWaalsContact C-CE1 3.43Å; A71-Y157 HydrophobicContact CB-CD1 4.42Å; A71-Y157 HydrophobicContact CB-CE1 3.62Å; A71-Y157 HydrophobicContact CB-CE2 4.05Å; A71-Y157 WeakPolarHBondContact CB-OH 3.32Å; A71-Y157 WeakPolarHBondContact O-CD1 3.49Å; A71-Y157 PolarHBondContact O-N 3.38Å; A71-F158 HydrophobicContact CB-CB 4.21Å; A71-F158 PolarHBondContact N-O 2.85Å; A71-F158 PolarHBondContact O-N 2.72Å
72Y98.6Very high96.7Very high0 Ų036.3 Ų36.30%024%0.238CC..EExtended strand (participates in β ladder)trans-140.4140.7-172.757.6-91.8000111.7I70 K90 G91 W102 L149 P154 M155I70-Y72 HydrophobicContact CG2-CD1 4.18Å; Y72-K90 CarbonylContact O-C 3.55Å; Y72-K90 VanDerWaalsContact O-CA 3.26Å; Y72-K90 WeakPolarHBondContact O-CA 3.5Å; Y72-G91 WeakPolarHBondContact CD1-O 3.43Å; Y72-G91 VanDerWaalsContact CE2-N 3.29Å; Y72-G91 PolarHBondContact N-O 2.81Å; Y72-G91 PolarHBondContact O-N 3.02Å; Y72-W102 PolarHBondContact OH-NE1 2.86Å; Y72-L149 HydrophobicContact CE1-CD1 4.29Å; Y72-P154 HydrophobicContact CD2-CB 3.42Å; Y72-P154 VanDerWaalsContact CD2-CB 3.42Å; Y72-P154 HydrophobicContact CD2-CG 4.25Å; Y72-P154 HydrophobicContact CE2-CB 4.11Å; Y72-P154 HydrophobicContact CG-CB 3.71Å; Y72-P154 HydrophobicContact CG-CG 4.22Å; Y72-M155 CarbonylContact C-O 3.19Å; Y72-M155 WeakPolarHBondContact CA-O 3.33Å; Y72-M155 WeakPolarHBondContact CB-O 3.36Å
73S98.4Very high96.7Very high5 Ų537.2 Ų37.24%0.03524%0.237CC..  trans-172.5135.5179179.70000109.9H75 A76 K90 M155S73-H75 PolarHBondContact O-N 2.89Å; S73-H75 PolarHBondContact OG-N 2.79Å; S73-H75 PolarHBondContact OG-O 2.76Å; S73-H75 VanDerWaalsContact OG-O 3.13Å; S73-A76 PolarHBondContact OG-N 2.99Å; S73-K90 WeakPolarHBondContact OG-CG 3.22Å; S73-M155 PolarHBondContact N-O 3.27Å
74N97.7Very high96.4Very high5 Ų542 Ų423%0.02726%0.259CS..THydrogen-bonded Turntrans-76.50.5166.368.9-31.3000113.3E82 L83 E86 S87 K90 M155N74-E82 VanDerWaalsContact ND2-CG 3.34Å; N74-E82 WeakPolarHBondContact ND2-CG 3.3Å; N74-E82 PolarHBondContact ND2-OE1 3Å; N74-E82 PolarHBondContact OD1-OE1 2.82Å; N74-L83 HydrophobicContact CB-CB 4.29Å; N74-L83 PolarHBondContact ND2-O 2.9Å; N74-L83 PolarHBondContact O-N 2.92Å; N74-E86 HydrophobicContact CB-CB 4.28Å; N74-S87 VanDerWaalsContact CB-O 3.26Å; N74-S87 WeakPolarHBondContact CB-O 3.09Å; N74-K90 VanDerWaalsContact OD1-CE 3.24Å; N74-K90 WeakPolarHBondContact OD1-CE 3.39Å; N74-K90 PolarHBondContact OD1-NZ 2.87Å; N74-M155 HydrophobicContact CB-CG 4.45Å
75H97.6Very high96Very high22 Ų2248.4 Ų48.410%0.10229%0.287CS..THydrogen-bonded Turntrans-137.359.6173.8-161168.8000108.1S73 E82 P108 K109S73-H75 PolarHBondContact O-N 2.89Å; S73-H75 PolarHBondContact OG-N 2.79Å; S73-H75 PolarHBondContact OG-O 2.76Å; S73-H75 VanDerWaalsContact OG-O 3.13Å; H75-E82 HydrophobicContact CB-CB 4.11Å; H75-E82 HydrophobicContact CB-CG 4.01Å; H75-E82 IonicContact ND1-OE2 3.55Å; H75-P108 HydrophobicContact CB-CB 4.45Å; H75-P108 VanDerWaalsContact ND1-CB 3.28Å; H75-P108 WeakPolarHBondContact ND1-CB 3.4Å; H75-K109 WeakPolarHBondContact NE2-CE 3.36Å; H75-K109 VanDerWaalsContact O-CA 3.28Å; H75-K109 WeakPolarHBondContact O-CA 3.38Å; H75-K109 PolarHBondContact O-N 2.8Å
76A97.3Very high95.9Very high17 Ų1747.5 Ų47.514%0.1428%0.28CS..  trans-64.8159.8-17600000112.4S73 G78 A79 Y157S73-A76 PolarHBondContact OG-N 2.99Å; A76-G78 PolarHBondContact O-N 2.88Å; A76-A79 WeakPolarHBondContact O-CB 3.25Å; A76-A79 PolarHBondContact O-N 2.79Å; A76-A79 VanDerWaalsContact O-N 3.09Å; A76-Y157 HydrophobicContact CB-CD1 3.82Å; A76-Y157 HydrophobicContact CB-CD2 4.16Å; A76-Y157 HydrophobicContact CB-CE1 4.45Å; A76-Y157 HydrophobicContact CB-CG 3.65Å
77P95.9Very high95.9Very high36 Ų3643.5 Ų43.523%0.23426%0.259CS..THydrogen-bonded Turntrans-51.3136.9171.8-20.126.5000111.9A79 P111 N112 Y157P77-A79 VanDerWaalsContact C-N 3.26Å; P77-A79 PolarHBondContact O-N 2.85Å; P77-P111 WeakPolarHBondContact CG-O 3.44Å; P77-N112 HydrophobicContact CB-CB 4.46Å; P77-N112 HydrophobicContact CG-CB 4.48Å; P77-Y157 HydrophobicContact CG-CE2 4.19Å
78G93.2Very high95.8Very high82 Ų8243.5 Ų43.585%0.84526%0.26SS*.THydrogen-bonded Turntrans81.8-12.1-176.900000115.5A76A76-G78 PolarHBondContact O-N 2.88Å
79A94.8Very high95.8Very high30 Ų3043.6 Ų43.625%0.24826%0.26CS..  trans-67.1140.3173.800000111.4A76 P77 K109A76-A79 WeakPolarHBondContact O-CB 3.25Å; A76-A79 PolarHBondContact O-N 2.79Å; A76-A79 VanDerWaalsContact O-N 3.09Å; P77-A79 VanDerWaalsContact C-N 3.26Å; P77-A79 PolarHBondContact O-N 2.85Å; A79-K109 WeakPolarHBondContact O-CE 3.46Å; A79-K109 PolarHBondContact O-NZ 3.25Å
80S93.4Very high95.8Very high104 Ų10444 Ų4473%0.72726%0.262SS*.SBendtrans-76.4-37.1175.953.70000112.1
81T95.8Very high95.8Very high90 Ų9044 Ų4455%0.55226%0.262SS*.SBendtrans-139.1157-176.559.30000111.8
82E95.6Very high95.8Very high64 Ų6444 Ų4430%0.29926%0.262SS..  trans-71.9140169.2-173.3159.9-166.500111.1N74 H75 D84 K90N74-E82 VanDerWaalsContact ND2-CG 3.34Å; N74-E82 WeakPolarHBondContact ND2-CG 3.3Å; N74-E82 PolarHBondContact ND2-OE1 3Å; N74-E82 PolarHBondContact OD1-OE1 2.82Å; H75-E82 HydrophobicContact CB-CB 4.11Å; H75-E82 HydrophobicContact CB-CG 4.01Å; H75-E82 IonicContact ND1-OE2 3.55Å; E82-D84 WeakPolarHBondContact CG-OD1 3.17Å; E82-D84 PolarHBondContact O-N 2.8Å; E82-K90 IonicContact OE1-NZ 3.66Å; E82-K90 PolarHBondContact OE1-NZ 3.42Å
83L95.5Very high95.8Very high88 Ų8844 Ų4446%0.46126%0.262SS..  trans-86.682.4172.9-57.9177.7000109.8N74 K85 E86N74-L83 HydrophobicContact CB-CB 4.29Å; N74-L83 PolarHBondContact ND2-O 2.9Å; N74-L83 PolarHBondContact O-N 2.92Å; L83-K85 PolarHBondContact O-N 2.6Å; L83-K85 VanDerWaalsContact O-N 3.12Å; L83-E86 HydrophobicContact CB-CB 4.15Å; L83-E86 HydrophobicContact CB-CG 3.9Å; L83-E86 HydrophobicContact CD1-CG 4.38Å; L83-E86 PolarHBondContact O-N 2.87Å
84D89.5Confident95.7Very high129 Ų12943.7 Ų43.769%0.6926%0.26SS*.THydrogen-bonded Turntrans-64.8-16.4-172.2-69.3-20.4000115.3E82E82-D84 WeakPolarHBondContact CG-OD1 3.17Å; E82-D84 PolarHBondContact O-N 2.8Å
85K89.8Confident95.7Very high165 Ų16543.8 Ų43.872%0.71726%0.26SS*.THydrogen-bonded Turntrans-88.1-12.8176.4-64.6-174.9-177.3175.60113.1L83L83-K85 PolarHBondContact O-N 2.6Å; L83-K85 VanDerWaalsContact O-N 3.12Å
86E94Very high95.5Very high64 Ų6446.1 Ų46.130%0.29927%0.271SS..SBendtrans-92.8174.2178.8-60.9-53.1143.600111.3N74 L83 M155N74-E86 HydrophobicContact CB-CB 4.28Å; L83-E86 HydrophobicContact CB-CB 4.15Å; L83-E86 HydrophobicContact CB-CG 3.9Å; L83-E86 HydrophobicContact CD1-CG 4.38Å; L83-E86 PolarHBondContact O-N 2.87Å; E86-M155 HydrophobicContact CB-CG 3.95Å; E86-M155 HydrophobicContact CB-SD 4.36Å; E86-M155 HydrophobicContact CG-CG 4.31Å; E86-M155 HydrophobicContact CG-SD 4.17Å
87S95.9Very high95.1Very high2 Ų250 Ų501%0.01429%0.289CS..  trans-55.8125.7176.5-177.20000111.2N74 S89 Q152 E153 S301N74-S87 VanDerWaalsContact CB-O 3.26Å; N74-S87 WeakPolarHBondContact CB-O 3.09Å; S87-S89 PolarHBondContact O-N 3.35Å; S87-S89 VanDerWaalsContact O-N 3.09Å; S87-S89 WeakPolarHBondContact OG-CB 3.03Å; S87-S89 PolarHBondContact OG-N 2.77Å; S87-S89 PolarHBondContact OG-OG 2.95Å; S87-Q152 VanDerWaalsContact CB-O 3.27Å; S87-Q152 WeakPolarHBondContact CB-O 3.04Å; S87-Q152 PolarHBondContact OG-O 3.11Å; S87-E153 WeakPolarHBondContact CB-O 3.43Å; S87-S301 WeakPolarHBondContact CB-OG 3.18Å; S87-S301 PolarHBondContact OG-OG 3.4Å
88P96.5Very high94.9Very high11 Ų1150.9 Ų50.97%0.07130%0.297CS..  trans-72.92.9175.631.4-35.4000113.1K90 N290 S301P88-K90 PolarHBondContact O-N 2.8Å; P88-N290 HydrophobicContact CB-CB 4.31Å; P88-N290 WeakPolarHBondContact CB-O 3.34Å; P88-N290 HydrophobicContact CG-CB 4.06Å; P88-N290 WeakPolarHBondContact CG-O 3.11Å; P88-S301 WeakPolarHBondContact CD-O 3.27Å
89S97.6Very high95Very high1 Ų149 Ų491%0.00727%0.267CS..  trans-62.8128.4-180-53.80000111.1S87 N290S87-S89 PolarHBondContact O-N 3.35Å; S87-S89 VanDerWaalsContact O-N 3.09Å; S87-S89 WeakPolarHBondContact OG-CB 3.03Å; S87-S89 PolarHBondContact OG-N 2.77Å; S87-S89 PolarHBondContact OG-OG 2.95Å; S89-N290 PolarHBondContact OG-ND2 3.14Å
90K98.5Very high95Very high8 Ų847.5 Ų47.54%0.03526%0.255CS..  trans-134138.5174.3-46.6179.3171.355.60110.5Y72 S73 N74 E82 P88 H105 L107Y72-K90 CarbonylContact O-C 3.55Å; Y72-K90 VanDerWaalsContact O-CA 3.26Å; Y72-K90 WeakPolarHBondContact O-CA 3.5Å; S73-K90 WeakPolarHBondContact OG-CG 3.22Å; N74-K90 VanDerWaalsContact OD1-CE 3.24Å; N74-K90 WeakPolarHBondContact OD1-CE 3.39Å; N74-K90 PolarHBondContact OD1-NZ 2.87Å; E82-K90 IonicContact OE1-NZ 3.66Å; E82-K90 PolarHBondContact OE1-NZ 3.42Å; P88-K90 PolarHBondContact O-N 2.8Å; K90-H105 WeakPolarHBondContact CB-CE1 3.47Å; K90-H105 PolarHBondContact O-N 2.97Å; K90-L107 WeakPolarHBondContact CD-O 3.24Å
91G98.4Very high95.1Very high0 Ų042.6 Ų42.60%022%0.221CC..EExtended strand (participates in β ladder)trans170179-179.100000115A71 Y72 V103 H105A71-G91 WeakPolarHBondContact CA-O 2.99Å; Y72-G91 WeakPolarHBondContact CD1-O 3.43Å; Y72-G91 VanDerWaalsContact CE2-N 3.29Å; Y72-G91 PolarHBondContact N-O 2.81Å; Y72-G91 PolarHBondContact O-N 3.02Å; G91-V103 CarbonylContact C-O 3.53Å; G91-V103 WeakPolarHBondContact CA-O 3.38Å; G91-H105 PolarHBondContact N-NE2 3.49Å
92M98.3Very high95.2Very high0 Ų038.3 Ų38.30%020%0.195CC..EExtended strand (participates in β ladder)trans-141.8138.7176.7-176.3-174.368.400110.2L57 I60 I69 I70 A71 W102 V103 P111 M113L57-M92 HydrophobicContact CD2-CE 3.3Å; L57-M92 HydrophobicContact CD2-SD 4.38Å; I60-M92 HydrophobicContact CD1-CE 3.53Å; I60-M92 HydrophobicContact CG2-CE 4.24Å; I60-M92 HydrophobicContact CG2-SD 4.24Å; I69-M92 HydrophobicContact CG2-CG 4.28Å; I69-M92 HydrophobicContact CG2-SD 4.49Å; I70-M92 CarbonylContact O-C 3.51Å; I70-M92 VanDerWaalsContact O-CA 3.25Å; I70-M92 WeakPolarHBondContact O-CA 3.18Å; A71-M92 HydrophobicContact CB-CB 4.28Å; A71-M92 HydrophobicContact CB-CG 4.13Å; M92-W102 WeakPolarHBondContact O-CA 3.29Å; M92-V103 PolarHBondContact N-O 3.47Å; M92-V103 PolarHBondContact O-N 2.87Å; M92-P111 HydrophobicContact CB-CG 4.39Å; M92-P111 HydrophobicContact SD-CG 4.18Å; M92-M113 HydrophobicContact SD-CE 4Å; M92-M113 HydrophobicContact SD-SD 3.68Å; M92-M113 VanDerWaalsContact SD-SD 3.68Å
93L98Very high95.3Very high0 Ų035.3 Ų35.30%018%0.18CC..EExtended strand (participates in β ladder)trans-112.8138.8167.6-72.1165.4000108.9I69 I70 W95 V101 W102 M142 L145 L149 F174I69-L93 VanDerWaalsContact CA-O 3.29Å; I69-L93 WeakPolarHBondContact CA-O 3.04Å; I70-L93 PolarHBondContact N-O 3.27Å; I70-L93 PolarHBondContact O-N 3.24Å; L93-W95 HydrophobicContact CB-CE3 4.28Å; L93-W95 HydrophobicContact CB-CZ3 3.86Å; L93-V101 WeakPolarHBondContact CA-O 3.3Å; L93-W102 HydrophobicContact CD2-CB 3.46Å; L93-W102 VanDerWaalsContact CD2-CB 3.46Å; L93-W102 HydrophobicContact CD2-CD2 4.34Å; L93-W102 HydrophobicContact CD2-CG 3.45Å; L93-W102 VanDerWaalsContact CD2-CG 3.45Å; L93-W102 HydrophobicContact CG-CG 4.34Å; L93-M142 HydrophobicContact CD2-CE 4.42Å; L93-L145 HydrophobicContact CD2-CD2 3.63Å; L93-L149 HydrophobicContact CD1-CD1 3.45Å; L93-L149 VanDerWaalsContact CD1-CD1 3.45Å; L93-L149 HydrophobicContact CG-CD1 4.46Å; L93-F174 HydrophobicContact CD1-CE1 3.94Å
94A97.7Very high95.4Very high0 Ų031.8 Ų31.80%016%0.162CC..EExtended strand (participates in β ladder)trans-141.6132.4168.900000110.9M1 I60 N68 I69 G100 V101M1-A94 HydrophobicContact SD-CB 4.15Å; I60-A94 HydrophobicContact CB-CB 4.45Å; I60-A94 HydrophobicContact CD1-CB 3.68Å; I60-A94 HydrophobicContact CG1-CB 3.81Å; I60-A94 HydrophobicContact CG2-CB 3.76Å; N68-A94 CarbonylContact O-C 3.44Å; N68-A94 VanDerWaalsContact O-CA 3.23Å; N68-A94 WeakPolarHBondContact O-CA 3.21Å; I69-A94 HydrophobicContact CG1-CB 4.16Å; A94-G100 CarbonylContact O-C 3.37Å; A94-G100 WeakPolarHBondContact O-CA 3.41Å; A94-V101 HydrophobicContact CB-CG1 3.97Å; A94-V101 PolarHBondContact N-O 2.89Å; A94-V101 PolarHBondContact O-N 2.95Å
95W95.7Very high95.9Very high6 Ų626.1 Ų26.12%0.02313%0.132CC..EExtended strand (participates in β ladder)trans-151.8163.317472.2109.6000112.8M1 N68 L93 M142 L167 L168 F174M1-W95 VanDerWaalsContact CE-CA 3.44Å; M1-W95 HydrophobicContact CE-CB 4.35Å; N68-W95 HydrophobicContact CB-CD2 3.73Å; N68-W95 HydrophobicContact CB-CE3 4.08Å; N68-W95 HydrophobicContact CB-CG 4.25Å; N68-W95 HydrophobicContact CB-CH2 4.47Å; N68-W95 HydrophobicContact CB-CZ2 4.08Å; N68-W95 HydrophobicContact CB-CZ3 4.43Å; N68-W95 WeakPolarHBondContact CB-O 3.23Å; N68-W95 PolarHBondContact N-O 2.78Å; N68-W95 PolarHBondContact O-N 2.75Å; L93-W95 HydrophobicContact CB-CE3 4.28Å; L93-W95 HydrophobicContact CB-CZ3 3.86Å; W95-M142 HydrophobicContact CB-CE 4.21Å; W95-M142 HydrophobicContact CD2-CE 3.33Å; W95-M142 HydrophobicContact CE3-CE 3.23Å; W95-M142 HydrophobicContact CG-CE 3.79Å; W95-M142 HydrophobicContact CH2-CE 3.87Å; W95-M142 HydrophobicContact CZ2-CE 4.03Å; W95-M142 HydrophobicContact CZ3-CE 3.53Å; W95-L167 HydrophobicContact CZ2-CB 4.37Å; W95-L167 VanDerWaalsContact NE1-CD1 3.32Å; W95-L168 HydrophobicContact CH2-CD2 2.99Å; W95-L168 HydrophobicContact CH2-CG 4.35Å; W95-L168 HydrophobicContact CZ2-CD2 3.42Å; W95-L168 VanDerWaalsContact CZ2-CD2 3.42Å; W95-L168 HydrophobicContact CZ3-CD2 3.7Å; W95-F174 AromaticContact CH2-CD1 3.88Å; W95-F174 HydrophobicContact CH2-CD1 3.88Å; W95-F174 AromaticContact CH2-CD2 3.72Å; W95-F174 HydrophobicContact CH2-CD2 3.72Å; W95-F174 AromaticContact CH2-CE1 3.58Å; W95-F174 HydrophobicContact CH2-CE1 3.58Å; W95-F174 AromaticContact CH2-CE2 3.4Å; W95-F174 HydrophobicContact CH2-CE2 3.4Å; W95-F174 VanDerWaalsContact CH2-CE2 3.4Å; W95-F174 AromaticContact CH2-CG 3.95Å; W95-F174 HydrophobicContact CH2-CG 3.95Å; W95-F174 AromaticContact CH2-CZ 3.32Å; W95-F174 HydrophobicContact CH2-CZ 3.32Å; W95-F174 AromaticContact CZ2-CD2 3.67Å; W95-F174 HydrophobicContact CZ2-CD2 3.67Å; W95-F174 HydrophobicContact CZ2-CE1 4.42Å; W95-F174 AromaticContact CZ2-CE2 3.39Å; W95-F174 HydrophobicContact CZ2-CE2 3.39Å; W95-F174 HydrophobicContact CZ2-CG 4.3Å; W95-F174 AromaticContact CZ2-CZ 3.81Å; W95-F174 HydrophobicContact CZ2-CZ 3.81Å; W95-F174 HydrophobicContact CZ3-CE1 4.26Å; W95-F174 HydrophobicContact CZ3-CZ 4.1Å
96E93.6Very high96.2Very high71 Ų7118.7 Ų18.733%0.33210%0.1SC..SBendtrans-116.9-135.3172.7-59.1-175.7-17000106.8M1 N66 K67 S98 L167M1-E96 HydrophobicContact CE-CB 4.47Å; M1-E96 HydrophobicContact CE-CG 4.1Å; N66-E96 WeakPolarHBondContact O-CG 3.35Å; K67-E96 WeakPolarHBondContact CE-OE1 3.34Å; K67-E96 HydrophobicContact CG-CG 3.84Å; K67-E96 WeakPolarHBondContact CG-OE1 3.39Å; K67-E96 IonicContact NZ-OE1 2.93Å; K67-E96 PolarHBondContact NZ-OE1 2.85Å; E96-S98 PolarHBondContact O-N 2.6Å; E96-L167 VanDerWaalsContact O-CD1 3.24Å; E96-L167 WeakPolarHBondContact O-CD1 3.49Å
97D90.3Very high96.4Very high98 Ų9815.7 Ų15.752%0.5249%0.086SC..SBendtrans-8926.3174.7-62.1-42.9000113.4Q139 S165D97-Q139 PolarHBondContact O-NE2 2.82Å; D97-Q139 PolarHBondContact O-OE1 2.9Å; D97-S165 WeakPolarHBondContact OD1-CB 3.15Å; D97-S165 PolarHBondContact OD1-OG 2.81Å
98S91.5Very high96.5Very high56 Ų5616.2 Ų16.239%0.3929%0.09SC..SBendtrans-145.7-171-17659.70000110.1E96 G100E96-S98 PolarHBondContact O-N 2.6Å; S98-G100 PolarHBondContact O-N 2.84Å
99D93.8Very high96.5Very high41 Ų4119.7 Ų19.722%0.21910%0.103CC..  trans-46.9134.9177.1-64.7-5.1000112.9M1 I136 V137 P138 Q139 T197M1-D99 WeakPolarHBondContact CE-O 3.31Å; D99-I136 HydrophobicContact CB-CG2 3.94Å; D99-V137 CarbonylContact C-O 3.51Å; D99-V137 WeakPolarHBondContact CA-O 3.47Å; D99-V137 WeakPolarHBondContact CB-O 3.47Å; D99-P138 WeakPolarHBondContact OD1-CA 3.48Å; D99-Q139 PolarHBondContact OD1-N 2.97Å; D99-T197 VanDerWaalsContact OD2-CB 3.29Å; D99-T197 WeakPolarHBondContact OD2-CB 3.44Å; D99-T197 WeakPolarHBondContact OD2-CG2 3.17Å; D99-T197 PolarHBondContact OD2-OG1 2.88Å
100G95.2Very high96.5Very high0 Ų019.9 Ų19.90%010%0.104CC..EExtended strand (participates in β ladder)trans-89.5164.317900000112.3A94 S98 I136 V137A94-G100 CarbonylContact O-C 3.37Å; A94-G100 WeakPolarHBondContact O-CA 3.41Å; S98-G100 PolarHBondContact O-N 2.84Å; G100-I136 CarbonylContact O-C 3.59Å; G100-I136 WeakPolarHBondContact O-CA 3.03Å; G100-V137 PolarHBondContact N-O 3.05Å; G100-V137 PolarHBondContact O-N 2.87Å
101V95.9Very high96.5Very high1 Ų119.6 Ų19.61%0.00610%0.103CC..EExtended strand (participates in β ladder)trans-112.8132.5165.958.70000109.9M1 C3 T56 I60 L93 A94 V103 C134 I136M1-V101 HydrophobicContact CB-CB 4.32Å; M1-V101 HydrophobicContact CB-CG1 3.98Å; M1-V101 HydrophobicContact CG-CG1 4.37Å; M1-V101 HydrophobicContact SD-CG1 4.18Å; C3-V101 VanDerWaalsContact SG-CG2 3.56Å; T56-V101 HydrophobicContact CG2-CG2 3.72Å; I60-V101 HydrophobicContact CD1-CG1 3.65Å; L93-V101 WeakPolarHBondContact CA-O 3.3Å; A94-V101 HydrophobicContact CB-CG1 3.97Å; A94-V101 PolarHBondContact N-O 2.89Å; A94-V101 PolarHBondContact O-N 2.95Å; V101-V103 HydrophobicContact CG2-CG2 4.27Å; V101-C134 WeakPolarHBondContact CG2-SG 3.37Å; V101-I136 HydrophobicContact CB-CD1 4.15Å; V101-I136 HydrophobicContact CG2-CD1 4.34Å
102W97.7Very high96.4Very high0 Ų021.5 Ų21.50%011%0.113CC..EExtended strand (participates in β ladder)trans-120115.6177.1-175.926000110.3Y72 M92 L93 L104 C134 I135 V137 L145 L149 L205 V305Y72-W102 PolarHBondContact OH-NE1 2.86Å; M92-W102 WeakPolarHBondContact O-CA 3.29Å; L93-W102 HydrophobicContact CD2-CB 3.46Å; L93-W102 VanDerWaalsContact CD2-CB 3.46Å; L93-W102 HydrophobicContact CD2-CD2 4.34Å; L93-W102 HydrophobicContact CD2-CG 3.45Å; L93-W102 VanDerWaalsContact CD2-CG 3.45Å; L93-W102 HydrophobicContact CG-CG 4.34Å; W102-L104 HydrophobicContact CD2-CD1 4.13Å; W102-L104 HydrophobicContact CD2-CG 4.13Å; W102-L104 HydrophobicContact CE3-CD1 4.22Å; W102-L104 HydrophobicContact CH2-CD1 3.87Å; W102-L104 HydrophobicContact CH2-CD2 4.36Å; W102-L104 HydrophobicContact CH2-CG 4.46Å; W102-L104 HydrophobicContact CZ2-CD1 3.76Å; W102-L104 HydrophobicContact CZ2-CD2 3.49Å; W102-L104 VanDerWaalsContact CZ2-CD2 3.49Å; W102-L104 HydrophobicContact CZ2-CG 3.84Å; W102-L104 HydrophobicContact CZ3-CD1 4.07Å; W102-C134 CarbonylContact O-C 3.47Å; W102-C134 WeakPolarHBondContact O-CA 3.48Å; W102-I135 HydrophobicContact CE3-CD1 4.15Å; W102-I135 HydrophobicContact CZ3-CD1 4.38Å; W102-I135 PolarHBondContact N-O 2.98Å; W102-I135 PolarHBondContact O-N 2.88Å; W102-V137 HydrophobicContact CB-CG2 3.75Å; W102-V137 HydrophobicContact CE3-CG2 4.44Å; W102-L145 HydrophobicContact CD2-CD1 4.31Å; W102-L145 HydrophobicContact CD2-CD2 4.08Å; W102-L145 HydrophobicContact CE3-CD1 4.03Å; W102-L145 HydrophobicContact CE3-CD2 4.06Å; W102-L145 HydrophobicContact CG-CD2 4.33Å; W102-L145 HydrophobicContact CH2-CD1 3.65Å; W102-L145 HydrophobicContact CZ2-CD1 3.94Å; W102-L145 HydrophobicContact CZ3-CD1 3.72Å; W102-L149 HydrophobicContact CZ2-CD2 3.89Å; W102-L205 HydrophobicContact CH2-CD2 3.49Å; W102-L205 VanDerWaalsContact CH2-CD2 3.49Å; W102-L205 HydrophobicContact CH2-CG 4.21Å; W102-L205 HydrophobicContact CZ3-CD2 3.64Å; W102-L205 HydrophobicContact CZ3-CG 4.21Å; W102-V305 HydrophobicContact CH2-CB 4.41Å; W102-V305 HydrophobicContact CH2-CG1 4.1Å; W102-V305 HydrophobicContact CH2-CG2 3.44Å; W102-V305 VanDerWaalsContact CH2-CG2 3.44Å; W102-V305 HydrophobicContact CZ2-CG2 4.2Å; W102-V305 HydrophobicContact CZ3-CG1 3.8Å; W102-V305 HydrophobicContact CZ3-CG2 4.05Å
103V98.1Very high96.4Very high0 Ų021.8 Ų21.80%011%0.114CC..EExtended strand (participates in β ladder)trans-105.8120.5175.4-176.20000108.9T56 G91 M92 V101 W110 I132 M133 C134T56-V103 HydrophobicContact CG2-CG2 4.19Å; G91-V103 CarbonylContact C-O 3.53Å; G91-V103 WeakPolarHBondContact CA-O 3.38Å; M92-V103 PolarHBondContact N-O 3.47Å; M92-V103 PolarHBondContact O-N 2.87Å; V101-V103 HydrophobicContact CG2-CG2 4.27Å; V103-W110 HydrophobicContact CG1-CH2 3.96Å; V103-W110 HydrophobicContact CG1-CZ3 3.99Å; V103-I132 HydrophobicContact CG1-CG2 3.73Å; V103-M133 CarbonylContact C-O 3.49Å; V103-M133 WeakPolarHBondContact CA-O 3.32Å; V103-C134 HydrophobicContact CG2-CB 4.39Å
104L98.2Very high96.2Very high15 Ų1528.8 Ų28.88%0.07915%0.152CC..EExtended strand (participates in β ladder)trans-105.6142171.3-69.6159.9000108.8W102 I132 M133 V305W102-L104 HydrophobicContact CD2-CD1 4.13Å; W102-L104 HydrophobicContact CD2-CG 4.13Å; W102-L104 HydrophobicContact CE3-CD1 4.22Å; W102-L104 HydrophobicContact CH2-CD1 3.87Å; W102-L104 HydrophobicContact CH2-CD2 4.36Å; W102-L104 HydrophobicContact CH2-CG 4.46Å; W102-L104 HydrophobicContact CZ2-CD1 3.76Å; W102-L104 HydrophobicContact CZ2-CD2 3.49Å; W102-L104 VanDerWaalsContact CZ2-CD2 3.49Å; W102-L104 HydrophobicContact CZ2-CG 3.84Å; W102-L104 HydrophobicContact CZ3-CD1 4.07Å; L104-I132 CarbonylContact O-C 3.54Å; L104-I132 VanDerWaalsContact O-CA 3.28Å; L104-I132 WeakPolarHBondContact O-CA 3.38Å; L104-M133 HydrophobicContact CB-CB 4.41Å; L104-M133 PolarHBondContact N-O 2.86Å; L104-M133 PolarHBondContact O-N 2.85Å; L104-V305 HydrophobicContact CD1-CB 3.84Å; L104-V305 HydrophobicContact CD1-CG1 3.91Å; L104-V305 HydrophobicContact CD1-CG2 3.67Å
105H98.3Very high96.2Very high10 Ų1029.4 Ų29.45%0.04616%0.157CC..EExtended strand (participates in β ladder)trans-152.7166.8176.562.892.3000114.1K90 G91 L107 W110 L131 I132K90-H105 WeakPolarHBondContact CB-CE1 3.47Å; K90-H105 PolarHBondContact O-N 2.97Å; G91-H105 PolarHBondContact N-NE2 3.49Å; H105-L107 HydrophobicContact CB-CG 4.44Å; H105-L107 PolarHBondContact CE1-O 3.22Å; H105-L107 VanDerWaalsContact CE1-O 3.3Å; H105-L107 PolarHBondContact ND1-N 3.24Å; H105-L107 PolarHBondContact ND1-O 3.36Å; H105-W110 HydrophobicContact CB-CZ3 4.29Å; H105-W110 AromaticContact CD2-CE3 3.57Å; H105-W110 AromaticContact CD2-CZ3 3.45Å; H105-W110 VanDerWaalsContact CD2-CZ3 3.45Å; H105-W110 WeakPolarHBondContact CD2-CZ3 3.32Å; H105-W110 AromaticContact CE1-CE3 3.78Å; H105-W110 PolarHBondContact CE1-O 3.12Å; H105-W110 AromaticContact CG-CE3 3.78Å; H105-W110 AromaticContact CG-CZ3 3.83Å; H105-W110 AromaticContact ND1-CE3 3.92Å; H105-W110 AromaticContact NE2-CE3 3.59Å; H105-W110 AromaticContact NE2-CZ3 3.9Å; H105-W110 PolarHBondContact NE2-O 2.89Å; H105-L131 CarbonylContact C-O 3.54Å; H105-L131 WeakPolarHBondContact CA-O 3.42Å; H105-I132 HydrophobicContact CB-CB 4.39Å; H105-I132 HydrophobicContact CB-CG1 3.99Å; H105-I132 HydrophobicContact CB-CG2 4.34Å
106T98Very high96.2Very high9 Ų933.8 Ų33.86%0.05519%0.188CC..  trans-107.93.7167.567.20000113.7A130 L131 T272T106-A130 VanDerWaalsContact OG1-CA 3.3Å; T106-A130 WeakPolarHBondContact OG1-CA 3.21Å; T106-A130 VanDerWaalsContact OG1-CB 3.3Å; T106-A130 WeakPolarHBondContact OG1-CB 3.23Å; T106-L131 PolarHBondContact N-O 3.23Å; T106-L131 PolarHBondContact OG1-N 2.66Å; T106-T272 WeakPolarHBondContact CB-O 3.47Å; T106-T272 PolarHBondContact OG1-OG1 2.85Å; T106-T272 VanDerWaalsContact OG1-OG1 3.08Å
107L97.7Very high96.3Very high0 Ų033 Ų330%019%0.186CC..  trans-63.9138.9177.4-61.1173.8000112.2K19 K90 H105 W110 F123 P124 A130 I132K19-L107 HydrophobicContact CD-CD2 3.53Å; K90-L107 WeakPolarHBondContact CD-O 3.24Å; H105-L107 HydrophobicContact CB-CG 4.44Å; H105-L107 PolarHBondContact CE1-O 3.22Å; H105-L107 VanDerWaalsContact CE1-O 3.3Å; H105-L107 PolarHBondContact ND1-N 3.24Å; H105-L107 PolarHBondContact ND1-O 3.36Å; L107-W110 HydrophobicContact CB-CB 4.23Å; L107-W110 HydrophobicContact CD1-CB 4.48Å; L107-W110 HydrophobicContact CD1-CD2 3.86Å; L107-W110 HydrophobicContact CD1-CE3 3.94Å; L107-W110 HydrophobicContact CD1-CG 4.12Å; L107-W110 HydrophobicContact CD1-CZ3 4.49Å; L107-F123 HydrophobicContact CD1-CE2 3.96Å; L107-F123 HydrophobicContact CD1-CZ 4.2Å; L107-P124 HydrophobicContact CB-CG 4.07Å; L107-P124 HydrophobicContact CD1-CG 4.1Å; L107-P124 HydrophobicContact CD2-CG 3.95Å; L107-P124 HydrophobicContact CG-CG 4.27Å; L107-A130 HydrophobicContact CD2-CB 3.34Å; L107-A130 HydrophobicContact CG-CB 4.06Å; L107-I132 HydrophobicContact CD1-CD1 3.61Å; L107-I132 HydrophobicContact CD1-CG1 4Å; L107-I132 HydrophobicContact CG-CD1 4.36Å; L107-I132 HydrophobicContact CG-CG1 4.29Å
108P97.3Very high96.5Very high14 Ų1428.8 Ų28.89%0.09116%0.164CC..SBendtrans-80.4157.4166.536.5-35.7000110.9H75 W110 E127H75-P108 HydrophobicContact CB-CB 4.45Å; H75-P108 VanDerWaalsContact ND1-CB 3.28Å; H75-P108 WeakPolarHBondContact ND1-CB 3.4Å; P108-W110 PolarHBondContact O-N 2.92Å; P108-W110 VanDerWaalsContact O-N 3.13Å; P108-E127 HydrophobicContact CG-CB 4.32Å; P108-E127 HydrophobicContact CG-CG 3.61Å
109K97.2Very high96.7Very high83 Ų8328.9 Ų28.936%0.36116%0.162SC..SBendtrans54.431.9169.3-54.6-174-171.4-165.40115.4H75 A79H75-K109 WeakPolarHBondContact NE2-CE 3.36Å; H75-K109 VanDerWaalsContact O-CA 3.28Å; H75-K109 WeakPolarHBondContact O-CA 3.38Å; H75-K109 PolarHBondContact O-N 2.8Å; A79-K109 WeakPolarHBondContact O-CE 3.46Å; A79-K109 PolarHBondContact O-NZ 3.25Å
110W98Very high96.7Very high6 Ų629.7 Ų29.72%0.02317%0.169CC..  trans-145.6150.9-174.9-176.391.2000111.4L53 L57 V103 H105 L107 P108 F123 P124L53-W110 HydrophobicContact CD1-CH2 4.09Å; L53-W110 HydrophobicContact CD1-CZ2 4.3Å; L53-W110 HydrophobicContact CD2-CH2 4.16Å; L53-W110 HydrophobicContact CD2-CZ2 3.76Å; L53-W110 HydrophobicContact CG-CH2 4.48Å; L53-W110 HydrophobicContact CG-CZ2 4.2Å; L57-W110 HydrophobicContact CD1-CH2 4.07Å; L57-W110 HydrophobicContact CD1-CZ2 3.34Å; L57-W110 HydrophobicContact CG-CZ2 4.39Å; V103-W110 HydrophobicContact CG1-CH2 3.96Å; V103-W110 HydrophobicContact CG1-CZ3 3.99Å; H105-W110 HydrophobicContact CB-CZ3 4.29Å; H105-W110 AromaticContact CD2-CE3 3.57Å; H105-W110 AromaticContact CD2-CZ3 3.45Å; H105-W110 VanDerWaalsContact CD2-CZ3 3.45Å; H105-W110 WeakPolarHBondContact CD2-CZ3 3.32Å; H105-W110 AromaticContact CE1-CE3 3.78Å; H105-W110 PolarHBondContact CE1-O 3.12Å; H105-W110 AromaticContact CG-CE3 3.78Å; H105-W110 AromaticContact CG-CZ3 3.83Å; H105-W110 AromaticContact ND1-CE3 3.92Å; H105-W110 AromaticContact NE2-CE3 3.59Å; H105-W110 AromaticContact NE2-CZ3 3.9Å; H105-W110 PolarHBondContact NE2-O 2.89Å; L107-W110 HydrophobicContact CB-CB 4.23Å; L107-W110 HydrophobicContact CD1-CB 4.48Å; L107-W110 HydrophobicContact CD1-CD2 3.86Å; L107-W110 HydrophobicContact CD1-CE3 3.94Å; L107-W110 HydrophobicContact CD1-CG 4.12Å; L107-W110 HydrophobicContact CD1-CZ3 4.49Å; P108-W110 PolarHBondContact O-N 2.92Å; P108-W110 VanDerWaalsContact O-N 3.13Å; W110-F123 AromaticContact NE1-CD2 3.95Å; W110-P124 HydrophobicContact CB-CG 4.22Å
111P97.1Very high96.7Very high2 Ų234.1 Ų34.11%0.01321%0.206CC..  cis-80.7153.1-10.732.7-35.8000113.3P77 M92 M113 Y157P77-P111 WeakPolarHBondContact CG-O 3.44Å; M92-P111 HydrophobicContact CB-CG 4.39Å; M92-P111 HydrophobicContact SD-CG 4.18Å; P111-M113 HydrophobicContact CB-SD 4.46Å; P111-M113 HydrophobicContact CG-SD 3.96Å; P111-M113 PolarHBondContact O-N 3.39Å; P111-M113 VanDerWaalsContact O-N 3.16Å; P111-Y157 VanDerWaalsContact CD-OH 3.23Å; P111-Y157 WeakPolarHBondContact CD-OH 3.49Å; P111-Y157 PolarHBondContact O-OH 3.16Å
112N97.1Very high96.7Very high40 Ų4036.7 Ų36.721%0.21422%0.219CC..  trans-76.798.8175.4-178.111.2000111.9P77 N114 A115 D122P77-N112 HydrophobicContact CB-CB 4.46Å; P77-N112 HydrophobicContact CG-CB 4.48Å; N112-N114 PolarHBondContact O-N 3.36Å; N112-N114 WeakPolarHBondContact OD1-CB 3.38Å; N112-N114 PolarHBondContact OD1-N 2.94Å; N112-N114 VanDerWaalsContact OD1-N 3.13Å; N112-A115 PolarHBondContact O-N 2.89Å; N112-D122 HydrophobicContact CB-CB 4.18Å; N112-D122 WeakPolarHBondContact CB-OD2 3.39Å; N112-D122 PolarHBondContact ND2-OD2 3.39Å
113M97.1Very high96.7Very high5 Ų537.2 Ų37.23%0.02522%0.222CC..THydrogen-bonded Turntrans-76.1-8.2-178.5-61.5-52.7-6000114.3L61 K64 I69 A71 M92 P111 Y157 F158L61-M113 HydrophobicContact CD2-CE 4.14Å; L61-M113 HydrophobicContact CD2-SD 4.1Å; K64-M113 HydrophobicContact CD-CE 4.34Å; K64-M113 WeakPolarHBondContact CE-O 3.4Å; I69-M113 HydrophobicContact CD1-CE 4.48Å; I69-M113 HydrophobicContact CG2-CE 3.66Å; A71-M113 HydrophobicContact CB-CG 3.71Å; A71-M113 HydrophobicContact CB-SD 4.18Å; M92-M113 HydrophobicContact SD-CE 4Å; M92-M113 HydrophobicContact SD-SD 3.68Å; M92-M113 VanDerWaalsContact SD-SD 3.68Å; P111-M113 HydrophobicContact CB-SD 4.46Å; P111-M113 HydrophobicContact CG-SD 3.96Å; P111-M113 PolarHBondContact O-N 3.39Å; P111-M113 VanDerWaalsContact O-N 3.16Å; M113-Y157 HydrophobicContact CB-CE2 4.2Å; M113-Y157 HydrophobicContact CG-CE2 3.71Å; M113-F158 HydrophobicContact CB-CB 3.79Å; M113-F158 HydrophobicContact CB-CD1 3.82Å; M113-F158 HydrophobicContact CB-CD2 3.55Å; M113-F158 HydrophobicContact CB-CE1 4.3Å; M113-F158 HydrophobicContact CB-CE2 4.05Å; M113-F158 HydrophobicContact CB-CG 3.42Å; M113-F158 VanDerWaalsContact CB-CG 3.42Å; M113-F158 HydrophobicContact CB-CZ 4.41Å; M113-F158 HydrophobicContact CE-CD1 3.74Å; M113-F158 HydrophobicContact CE-CE1 3.68Å; M113-F158 HydrophobicContact CE-CG 4.5Å; M113-F158 HydrophobicContact CE-CZ 4.37Å; M113-F158 HydrophobicContact CG-CB 3.83Å; M113-F158 HydrophobicContact CG-CD1 3.88Å; M113-F158 HydrophobicContact CG-CD2 4.42Å; M113-F158 HydrophobicContact CG-CG 3.79Å
114N95.6Very high96.6Very high147 Ų14738 Ų3879%0.78623%0.227SC*.THydrogen-bonded Turntrans-80.1-22173.5-65.5-20.8000112.3N112N112-N114 PolarHBondContact O-N 3.36Å; N112-N114 WeakPolarHBondContact OD1-CB 3.38Å; N112-N114 PolarHBondContact OD1-N 2.94Å; N112-N114 VanDerWaalsContact OD1-N 3.13Å
115A96.1Very high96.5Very high13 Ų1338.9 Ų38.911%0.10724%0.236CC..  trans-66.7135.4176.700000110.6K64 N112 D117 V119K64-A115 PolarHBondContact NZ-O 3.03Å; N112-A115 PolarHBondContact O-N 2.89Å; A115-D117 VanDerWaalsContact C-N 3.32Å; A115-D117 WeakPolarHBondContact CB-O 3.41Å; A115-V119 HydrophobicContact CB-CG2 4.04Å
116S96.4Very high96.4Very high98 Ų9842.7 Ų42.769%0.68526%0.264SS*.SBendtrans-84.3-6.4176.152.20000113.6L61 S62L61-S116 CarbonylContact C-O 3.47Å; S62-S116 VanDerWaalsContact CA-O 3.26Å; S62-S116 WeakPolarHBondContact CA-O 3.44Å; S62-S116 PolarHBondContact N-O 2.92Å
117D96.2Very high96.3Very high54 Ų5445.4 Ų45.429%0.28928%0.276SS..SBendtrans-147173.7176.9-1604.6000109.9K58 L61 S62 A115 V119K58-D117 WeakPolarHBondContact CD-OD1 3.37Å; K58-D117 WeakPolarHBondContact CE-OD1 3.49Å; K58-D117 WeakPolarHBondContact CE-OD2 3.44Å; K58-D117 VanDerWaalsContact CG-OD1 3.29Å; K58-D117 WeakPolarHBondContact CG-OD1 3.17Å; K58-D117 IonicContact NZ-OD1 2.87Å; K58-D117 PolarHBondContact NZ-OD1 3.39Å; K58-D117 IonicContact NZ-OD2 2.85Å; K58-D117 PolarHBondContact NZ-OD2 2.85Å; L61-D117 WeakPolarHBondContact CD1-O 3.43Å; S62-D117 PolarHBondContact OG-OD1 3.16Å; A115-D117 VanDerWaalsContact C-N 3.32Å; A115-D117 WeakPolarHBondContact CB-O 3.41Å; D117-V119 PolarHBondContact O-N 3.38Å
118F94.5Very high96.3Very high10 Ų1049.1 Ų49.14%0.04429%0.292CS..  trans-68.2116.1168.5-176.4-94.4000110.2L44 S45 D47 R54 L57 K58L44-F118 WeakPolarHBondContact O-CZ 3.49Å; S45-F118 WeakPolarHBondContact O-CE1 3.2Å; D47-F118 HydrophobicContact CB-CD1 4.12Å; R54-F118 HydrophobicContact CB-CD1 4.02Å; R54-F118 HydrophobicContact CB-CD2 4.11Å; R54-F118 HydrophobicContact CB-CE1 3.8Å; R54-F118 HydrophobicContact CB-CE2 3.9Å; R54-F118 HydrophobicContact CB-CG 4.17Å; R54-F118 HydrophobicContact CB-CZ 3.75Å; R54-F118 HydrophobicContact CG-CB 4.28Å; R54-F118 HydrophobicContact CG-CD1 3.52Å; R54-F118 HydrophobicContact CG-CD2 4.14Å; R54-F118 HydrophobicContact CG-CE1 3.78Å; R54-F118 HydrophobicContact CG-CE2 4.36Å; R54-F118 HydrophobicContact CG-CG 3.71Å; R54-F118 HydrophobicContact CG-CZ 4.2Å; L57-F118 HydrophobicContact CB-CD2 3.95Å; L57-F118 HydrophobicContact CB-CE2 4.48Å; L57-F118 HydrophobicContact CD1-CD2 4.13Å; L57-F118 HydrophobicContact CD1-CE2 4.02Å; K58-F118 HydrophobicContact CB-CB 3.87Å; K58-F118 HydrophobicContact CD-CB 3.97Å; K58-F118 HydrophobicContact CG-CB 4.41Å
119V95.3Very high96.4Very high59 Ų5948.4 Ų48.436%0.35829%0.288SS..  trans-110.3114.7-177.7178.30000109.1A115 D117 A121 D122A115-V119 HydrophobicContact CB-CG2 4.04Å; D117-V119 PolarHBondContact O-N 3.38Å; V119-A121 VanDerWaalsContact C-N 3.26Å; V119-A121 HydrophobicContact CG1-CB 4.24Å; V119-A121 PolarHBondContact O-N 3.01Å; V119-D122 HydrophobicContact CB-CB 4.32Å; V119-D122 WeakPolarHBondContact O-CB 3.39Å; V119-D122 PolarHBondContact O-N 3.43Å
120P94.1Very high96.4Very high58 Ų5844.5 Ų44.538%0.37727%0.271SS..G310 helixtrans-51.7-41.5179.9-33.438000114.7S45 D47 D122 F123S45-P120 WeakPolarHBondContact O-CA 3.34Å; S45-P120 WeakPolarHBondContact O-CB 3.46Å; S45-P120 WeakPolarHBondContact O-CG 3.27Å; D47-P120 HydrophobicContact CB-CG 4.24Å; P120-D122 PolarHBondContact O-N 2.55Å; P120-F123 PolarHBondContact O-N 3.01Å; P120-F123 VanDerWaalsContact O-N 3.15Å
121A95Very high96.4Very high92 Ų9244.2 Ų44.276%0.7627%0.27SS*.G310 helixtrans-66.3-17.1-17900000114.2V119 F123V119-A121 VanDerWaalsContact C-N 3.26Å; V119-A121 HydrophobicContact CG1-CB 4.24Å; V119-A121 PolarHBondContact O-N 3.01Å; A121-F123 VanDerWaalsContact C-N 3.31Å
122D95.8Very high96.5Very high55 Ų5544.1 Ų44.129%0.29427%0.269SS..G310 helixtrans-80.7-12.9177.3-73.5-15.7000112.4N112 V119 P120N112-D122 HydrophobicContact CB-CB 4.18Å; N112-D122 WeakPolarHBondContact CB-OD2 3.39Å; N112-D122 PolarHBondContact ND2-OD2 3.39Å; V119-D122 HydrophobicContact CB-CB 4.32Å; V119-D122 WeakPolarHBondContact O-CB 3.39Å; V119-D122 PolarHBondContact O-N 3.43Å; P120-D122 PolarHBondContact O-N 2.55Å
123F97.4Very high96.5Very high11 Ų1142.2 Ų42.25%0.04826%0.259CS..SBendtrans-74.3126.2174.6-167.2-93.2000110.3K19 A24 L44 L53 L107 W110 P120 A121 A125 I132K19-F123 HydrophobicContact CD-CE1 3.99Å; K19-F123 HydrophobicContact CD-CZ 4.13Å; K19-F123 HydrophobicContact CG-CE1 4.14Å; K19-F123 HydrophobicContact CG-CZ 4.18Å; A24-F123 HydrophobicContact CB-CD1 3.88Å; A24-F123 HydrophobicContact CB-CE1 4.13Å; L44-F123 HydrophobicContact CB-CD2 4.2Å; L44-F123 HydrophobicContact CB-CE1 4.11Å; L44-F123 HydrophobicContact CB-CE2 3.64Å; L44-F123 HydrophobicContact CB-CZ 3.6Å; L44-F123 HydrophobicContact CD1-CE2 4.08Å; L44-F123 HydrophobicContact CD1-CZ 3.77Å; L44-F123 HydrophobicContact CG-CZ 4.32Å; L53-F123 HydrophobicContact CD2-CE2 3.98Å; L107-F123 HydrophobicContact CD1-CE2 3.96Å; L107-F123 HydrophobicContact CD1-CZ 4.2Å; W110-F123 AromaticContact NE1-CD2 3.95Å; P120-F123 PolarHBondContact O-N 3.01Å; P120-F123 VanDerWaalsContact O-N 3.15Å; A121-F123 VanDerWaalsContact C-N 3.31Å; F123-A125 PolarHBondContact O-N 3.31Å; F123-I132 HydrophobicContact CE2-CD1 4.27Å; F123-I132 HydrophobicContact CZ-CD1 4.47Å
124P96.5Very high96.5Very high18 Ų1842 Ų4212%0.11726%0.258CS..  trans-78.765.7-172.932.9-37.6000112.3K19 L107 W110 S126 E127K19-P124 WeakPolarHBondContact CE-O 3.41Å; L107-P124 HydrophobicContact CB-CG 4.07Å; L107-P124 HydrophobicContact CD1-CG 4.1Å; L107-P124 HydrophobicContact CD2-CG 3.95Å; L107-P124 HydrophobicContact CG-CG 4.27Å; W110-P124 HydrophobicContact CB-CG 4.22Å; P124-S126 PolarHBondContact O-N 3.41Å; P124-E127 HydrophobicContact CB-CB 4.36Å; P124-E127 HydrophobicContact CB-CG 3.78Å; P124-E127 WeakPolarHBondContact O-CB 3.44Å; P124-E127 PolarHBondContact O-N 3.16Å
125A96.2Very high96.5Very high33 Ų3335 Ų3527%0.27322%0.22SC..THydrogen-bonded Turntrans-60.4-41.2-17400000113.2K19 R22 T23 A24 F123 E127K19-A125 PolarHBondContact NZ-O 3.25Å; K19-A125 VanDerWaalsContact NZ-O 3.11Å; R22-A125 CarbonylContact C-O 3.46Å; R22-A125 WeakPolarHBondContact CA-O 3.11Å; T23-A125 CarbonylContact C-O 3.56Å; T23-A125 PolarHBondContact N-O 2.78Å; T23-A125 VanDerWaalsContact O-O 3.1Å; A24-A125 HydrophobicContact CB-CB 3.91Å; F123-A125 PolarHBondContact O-N 3.31Å; A125-E127 PolarHBondContact O-N 3.48Å; A125-E127 VanDerWaalsContact O-N 3.13Å
126S96Very high96.4Very high89 Ų8934.5 Ų34.562%0.62222%0.216SC*.THydrogen-bonded Turntrans-68.7-9.2-178.659.40000114.1R22 P124R22-S126 WeakPolarHBondContact CD-O 3.4Å; R22-S126 PolarHBondContact NH1-O 3.14Å; P124-S126 PolarHBondContact O-N 3.41Å
127E96.5Very high96.4Very high66 Ų6629.9 Ų29.931%0.30818%0.183SC..SBendtrans-76.6172.2-178.4-68.2-65.1168.600113.2K19 R22 P108 P124 A125K19-E127 PolarHBondContact NZ-O 3.49Å; R22-E127 PolarHBondContact N-O 2.84Å; P108-E127 HydrophobicContact CG-CB 4.32Å; P108-E127 HydrophobicContact CG-CG 3.61Å; P124-E127 HydrophobicContact CB-CB 4.36Å; P124-E127 HydrophobicContact CB-CG 3.78Å; P124-E127 WeakPolarHBondContact O-CB 3.44Å; P124-E127 PolarHBondContact O-N 3.16Å; A125-E127 PolarHBondContact O-N 3.48Å; A125-E127 VanDerWaalsContact O-N 3.13Å
128K97.7Very high96.4Very high78 Ų7827.5 Ų27.534%0.33917%0.171SC..PPolyproline II helixtrans-59.1172.2174.7-72.7-176.4-176.4-168.80111.7K19 R22 D269 D270 T272K19-K128 PolarHBondContact NZ-O 3.01Å; K19-K128 VanDerWaalsContact NZ-O 3.08Å; R22-K128 VanDerWaalsContact NH1-N 3.19Å; K128-D269 WeakPolarHBondContact CD-O 3.31Å; K128-D269 WeakPolarHBondContact CE-O 3.39Å; K128-D269 PolarHBondContact NZ-O 2.87Å; K128-D270 WeakPolarHBondContact CB-O 3.35Å; K128-T272 HydrophobicContact CB-CG2 3.79Å; K128-T272 HydrophobicContact CD-CG2 4Å; K128-T272 HydrophobicContact CG-CG2 4.49Å
129A98.2Very high96.4Very high0 Ų031.6 Ų31.60%019%0.191CC..BIsolated β-bridgetrans-59.6147.6167.200000109.8Y18 K19 P21 I266 D270 D271 T272Y18-A129 HydrophobicContact CE1-CB 4.27Å; K19-A129 WeakPolarHBondContact O-CA 3.09Å; K19-A129 WeakPolarHBondContact O-CB 3.27Å; P21-A129 HydrophobicContact CB-CB 4.3Å; A129-I266 HydrophobicContact CB-CD1 4.1Å; A129-I266 HydrophobicContact CB-CG2 3.73Å; A129-D270 WeakPolarHBondContact CB-O 3.46Å; A129-D270 PolarHBondContact N-O 3.01Å; A129-D271 HydrophobicContact CB-CB 4.23Å; A129-T272 PolarHBondContact O-N 3.41Å; A129-T272 PolarHBondContact O-OG1 3.34Å
130A98.3Very high96.4Very high1 Ų136 Ų361%0.00821%0.207CC..EExtended strand (participates in β ladder)trans-153.9159.3-17500000110Y18 K19 T106 L107Y18-A130 CarbonylContact C-O 3.59Å; K19-A130 HydrophobicContact CB-CB 4.39Å; K19-A130 HydrophobicContact CD-CB 4.38Å; K19-A130 PolarHBondContact N-O 3.44Å; K19-A130 PolarHBondContact O-N 2.93Å; K19-A130 VanDerWaalsContact O-N 3.08Å; T106-A130 VanDerWaalsContact OG1-CA 3.3Å; T106-A130 WeakPolarHBondContact OG1-CA 3.21Å; T106-A130 VanDerWaalsContact OG1-CB 3.3Å; T106-A130 WeakPolarHBondContact OG1-CB 3.23Å; L107-A130 HydrophobicContact CD2-CB 3.34Å; L107-A130 HydrophobicContact CG-CB 4.06Å
131L98.2Very high96.5Very high0 Ų033.5 Ų33.50%019%0.191CC..EExtended strand (participates in β ladder)trans-113.9135178.5-166.860.8000109.2I16 Y18 H105 T106 W275 F286 V288I16-L131 HydrophobicContact CG2-CD1 3.65Å; Y18-L131 HydrophobicContact CD2-CD1 3.73Å; Y18-L131 HydrophobicContact CE2-CD1 4.33Å; Y18-L131 HydrophobicContact CG-CD1 4.01Å; H105-L131 CarbonylContact C-O 3.54Å; H105-L131 WeakPolarHBondContact CA-O 3.42Å; T106-L131 PolarHBondContact N-O 3.23Å; T106-L131 PolarHBondContact OG1-N 2.66Å; L131-W275 HydrophobicContact CD2-CB 4.18Å; L131-F286 HydrophobicContact CD2-CZ 4.17Å; L131-V288 HydrophobicContact CD2-CB 4.41Å; L131-V288 HydrophobicContact CD2-CG1 4.17Å; L131-V288 HydrophobicContact CD2-CG2 3.55Å; L131-V288 HydrophobicContact CG-CG2 4.21Å
132I98.4Very high96.6Very high0 Ų029.4 Ų29.40%016%0.157CC..EExtended strand (participates in β ladder)trans-122.9134.3172.6-50.3168.7000106.7I16 F17 L44 L53 V103 L104 H105 L107 F123I16-I132 WeakPolarHBondContact CA-O 3.46Å; F17-I132 HydrophobicContact CB-CB 4.14Å; F17-I132 HydrophobicContact CD2-CB 3.94Å; F17-I132 HydrophobicContact CD2-CG2 3.93Å; F17-I132 PolarHBondContact N-O 2.6Å; F17-I132 PolarHBondContact O-N 2.85Å; L44-I132 HydrophobicContact CD1-CD1 3.9Å; L53-I132 HydrophobicContact CD1-CG2 4.34Å; L53-I132 HydrophobicContact CD2-CD1 3.78Å; V103-I132 HydrophobicContact CG1-CG2 3.73Å; L104-I132 CarbonylContact O-C 3.54Å; L104-I132 VanDerWaalsContact O-CA 3.28Å; L104-I132 WeakPolarHBondContact O-CA 3.38Å; H105-I132 HydrophobicContact CB-CB 4.39Å; H105-I132 HydrophobicContact CB-CG1 3.99Å; H105-I132 HydrophobicContact CB-CG2 4.34Å; L107-I132 HydrophobicContact CD1-CD1 3.61Å; L107-I132 HydrophobicContact CD1-CG1 4Å; L107-I132 HydrophobicContact CG-CD1 4.36Å; L107-I132 HydrophobicContact CG-CG1 4.29Å; F123-I132 HydrophobicContact CE2-CD1 4.27Å; F123-I132 HydrophobicContact CZ-CD1 4.47Å
133M97.7Very high96.6Very high0 Ų028.6 Ų28.60%016%0.155CC..EExtended strand (participates in β ladder)trans-128.1122173.9173.7179.1-83.600108.1G15 I16 V103 L104 I135 F286 V288 V305 I307G15-M133 CarbonylContact O-C 3.59Å; G15-M133 WeakPolarHBondContact O-CA 3.43Å; I16-M133 HydrophobicContact CD1-CE 3.92Å; I16-M133 HydrophobicContact CG1-CE 3.84Å; I16-M133 HydrophobicContact CG1-CG 4.46Å; V103-M133 CarbonylContact C-O 3.49Å; V103-M133 WeakPolarHBondContact CA-O 3.32Å; L104-M133 HydrophobicContact CB-CB 4.41Å; L104-M133 PolarHBondContact N-O 2.86Å; L104-M133 PolarHBondContact O-N 2.85Å; M133-I135 HydrophobicContact CG-CD1 4.07Å; M133-I135 HydrophobicContact CG-CG1 3.97Å; M133-I135 HydrophobicContact SD-CD1 3.77Å; M133-I135 HydrophobicContact SD-CG1 4.27Å; M133-F286 HydrophobicContact CE-CD1 4.02Å; M133-F286 HydrophobicContact CE-CE1 3.64Å; M133-V288 HydrophobicContact CB-CG2 4.17Å; M133-V288 HydrophobicContact CE-CB 4.27Å; M133-V288 HydrophobicContact CE-CG2 3.37Å; M133-V288 HydrophobicContact SD-CB 4.27Å; M133-V288 HydrophobicContact SD-CG2 3.9Å; M133-V305 HydrophobicContact SD-CG1 4.37Å; M133-I307 HydrophobicContact CE-CD1 3.77Å; M133-I307 HydrophobicContact CE-CG1 4.11Å; M133-I307 HydrophobicContact SD-CD1 4.38Å
134C96.7Very high96.6Very high0 Ų030 Ų300%016%0.164CC..EExtended strand (participates in β ladder)trans-103133.8171.2-170.90000108.7C3 W14 G15 F17 V101 W102 V103C3-C134 WeakPolarHBondContact CA-SG 3.21Å; C3-C134 HydrophobicContact CB-CB 3.65Å; C3-C134 WeakPolarHBondContact CB-SG 3.36Å; C3-C134 VanDerWaalsContact SG-CA 3.6Å; C3-C134 WeakPolarHBondContact SG-CB 3.42Å; C3-C134 CovalentContact SG-SG 2.04Å; C3-C134 PolarHBondContact SG-SG 2.75Å; W14-C134 CarbonylContact C-O 3.52Å; W14-C134 WeakPolarHBondContact CA-O 3.47Å; W14-C134 WeakPolarHBondContact CB-O 3.29Å; G15-C134 PolarHBondContact N-O 3.03Å; G15-C134 PolarHBondContact O-N 3.15Å; F17-C134 HydrophobicContact CE2-CB 4.11Å; V101-C134 WeakPolarHBondContact CG2-SG 3.37Å; W102-C134 CarbonylContact O-C 3.47Å; W102-C134 WeakPolarHBondContact O-CA 3.48Å; V103-C134 HydrophobicContact CG2-CB 4.39Å
135I95.6Very high96.7Very high0 Ų029.1 Ų29.10%016%0.159CC..EExtended strand (participates in β ladder)trans-130.3134.3175.3-62.1164.8000109.4C3 D13 W14 W102 M133 V137 F194 I203 V305C3-I135 VanDerWaalsContact SG-CA 3.59Å; C3-I135 PolarHBondContact SG-N 2.83Å; D13-I135 CarbonylContact O-C 3.58Å; W14-I135 HydrophobicContact CB-CG1 4.24Å; W102-I135 HydrophobicContact CE3-CD1 4.15Å; W102-I135 HydrophobicContact CZ3-CD1 4.38Å; W102-I135 PolarHBondContact N-O 2.98Å; W102-I135 PolarHBondContact O-N 2.88Å; M133-I135 HydrophobicContact CG-CD1 4.07Å; M133-I135 HydrophobicContact CG-CG1 3.97Å; M133-I135 HydrophobicContact SD-CD1 3.77Å; M133-I135 HydrophobicContact SD-CG1 4.27Å; I135-V137 HydrophobicContact CG2-CG2 4.25Å; I135-F194 HydrophobicContact CG2-CE2 4.12Å; I135-F194 HydrophobicContact CG2-CZ 4.11Å; I135-I203 HydrophobicContact CD1-CG2 4.05Å; I135-I203 HydrophobicContact CG2-CG1 4.31Å; I135-V305 HydrophobicContact CD1-CG1 3.74Å
136I94.6Very high96.8Very high3 Ų327.6 Ų27.62%0.01515%0.146CC..EExtended strand (participates in β ladder)trans-79.3121.7163.1-61.3-56.3000108.4C3 D13 D99 G100 V101 F198C3-I136 HydrophobicContact CB-CD1 4.22Å; C3-I136 HydrophobicContact CB-CG1 4.17Å; D13-I136 PolarHBondContact O-N 3.44Å; D99-I136 HydrophobicContact CB-CG2 3.94Å; G100-I136 CarbonylContact O-C 3.59Å; G100-I136 WeakPolarHBondContact O-CA 3.03Å; V101-I136 HydrophobicContact CB-CD1 4.15Å; V101-I136 HydrophobicContact CG2-CD1 4.34Å; I136-F198 HydrophobicContact CG2-CE2 4.44Å
137V95.6Very high96.8Very high0 Ų026 Ų260%013%0.129CC..EExtended strand (participates in β ladder)trans-105.2121.8-177.2-176.50000107.3D99 G100 W102 I135 A141 M142 L145 F194D99-V137 CarbonylContact C-O 3.51Å; D99-V137 WeakPolarHBondContact CA-O 3.47Å; D99-V137 WeakPolarHBondContact CB-O 3.47Å; G100-V137 PolarHBondContact N-O 3.05Å; G100-V137 PolarHBondContact O-N 2.87Å; W102-V137 HydrophobicContact CB-CG2 3.75Å; W102-V137 HydrophobicContact CE3-CG2 4.44Å; I135-V137 HydrophobicContact CG2-CG2 4.25Å; V137-A141 HydrophobicContact CG1-CB 3.93Å; V137-M142 HydrophobicContact CB-SD 3.62Å; V137-M142 HydrophobicContact CG1-CG 4.26Å; V137-M142 HydrophobicContact CG1-SD 3.47Å; V137-M142 WeakPolarHBondContact CG1-SD 3.39Å; V137-M142 HydrophobicContact CG2-SD 4.48Å; V137-L145 HydrophobicContact CB-CD2 4.46Å; V137-L145 HydrophobicContact CG1-CD2 3.99Å; V137-L145 HydrophobicContact CG2-CD2 3.86Å; V137-F194 HydrophobicContact CB-CZ 4.48Å; V137-F194 HydrophobicContact CG1-CE1 4.41Å; V137-F194 HydrophobicContact CG1-CE2 4.36Å; V137-F194 HydrophobicContact CG1-CZ 4.13Å; V137-F194 HydrophobicContact CG2-CE2 4.46Å; V137-F194 HydrophobicContact CG2-CZ 4.01Å
138P95.6Very high96.9Very high5 Ų522.9 Ų22.93%0.03212%0.115CC..  trans-62.8144.9178.730.1-37000109.7D99 E140 A141 M142 F194 L195D99-P138 WeakPolarHBondContact OD1-CA 3.48Å; P138-E140 PolarHBondContact O-N 2.87Å; P138-E140 VanDerWaalsContact O-N 3.12Å; P138-A141 HydrophobicContact CG-CB 3.75Å; P138-A141 PolarHBondContact O-N 2.84Å; P138-M142 PolarHBondContact O-N 3.13Å; P138-F194 HydrophobicContact CG-CD2 4.07Å; P138-L195 WeakPolarHBondContact CG-O 3.1Å
139Q94.5Very high96.9Very high96 Ų9619.2 Ų19.245%0.44910%0.098SC..G310 helixtrans-50.5-41.2-175.8-173.9179.413.200112.7D97 D99 A141 M142D97-Q139 PolarHBondContact O-NE2 2.82Å; D97-Q139 PolarHBondContact O-OE1 2.9Å; D99-Q139 PolarHBondContact OD1-N 2.97Å; Q139-A141 PolarHBondContact O-N 3.3Å; Q139-M142 WeakPolarHBondContact O-CB 3.39Å; Q139-M142 PolarHBondContact O-N 2.66Å
140E95.1Very high96.9Very high150 Ų15019.8 Ų19.870%0.70110%0.102SC*.G310 helixtrans-65.2-22.4179.665.9-91.4-160.400114.4P138P138-E140 PolarHBondContact O-N 2.87Å; P138-E140 VanDerWaalsContact O-N 3.12Å
141A97.1Very high96.9Very high6 Ų620.8 Ų20.85%0.0511%0.106CC..G310 helixtrans-88.6-15.8179.300000113V137 P138 Q139 S143 T144 L145 F194V137-A141 HydrophobicContact CG1-CB 3.93Å; P138-A141 HydrophobicContact CG-CB 3.75Å; P138-A141 PolarHBondContact O-N 2.84Å; Q139-A141 PolarHBondContact O-N 3.3Å; A141-S143 PolarHBondContact O-N 2.84Å; A141-T144 PolarHBondContact O-N 2.97Å; A141-T144 PolarHBondContact O-OG1 3.01Å; A141-L145 PolarHBondContact O-N 2.84Å; A141-F194 HydrophobicContact CB-CB 3.75Å; A141-F194 HydrophobicContact CB-CD1 4.01Å; A141-F194 HydrophobicContact CB-CD2 4.44Å; A141-F194 HydrophobicContact CB-CG 3.84Å
142M96.5Very high96.9Very high7 Ų720.8 Ų20.83%0.03411%0.106CC..Hα-helixtrans-56.4-48.9-172.6-72.9-59.8-61.300113.2L93 W95 V137 P138 Q139 T144 L145 G146 F174L93-M142 HydrophobicContact CD2-CE 4.42Å; W95-M142 HydrophobicContact CB-CE 4.21Å; W95-M142 HydrophobicContact CD2-CE 3.33Å; W95-M142 HydrophobicContact CE3-CE 3.23Å; W95-M142 HydrophobicContact CG-CE 3.79Å; W95-M142 HydrophobicContact CH2-CE 3.87Å; W95-M142 HydrophobicContact CZ2-CE 4.03Å; W95-M142 HydrophobicContact CZ3-CE 3.53Å; V137-M142 HydrophobicContact CB-SD 3.62Å; V137-M142 HydrophobicContact CG1-CG 4.26Å; V137-M142 HydrophobicContact CG1-SD 3.47Å; V137-M142 WeakPolarHBondContact CG1-SD 3.39Å; V137-M142 HydrophobicContact CG2-SD 4.48Å; P138-M142 PolarHBondContact O-N 3.13Å; Q139-M142 WeakPolarHBondContact O-CB 3.39Å; Q139-M142 PolarHBondContact O-N 2.66Å; M142-T144 PolarHBondContact O-N 3.26Å; M142-L145 WeakPolarHBondContact O-CB 3.5Å; M142-L145 PolarHBondContact O-N 2.79Å; M142-L145 VanDerWaalsContact O-N 3.16Å; M142-G146 PolarHBondContact O-N 3.37Å; M142-F174 HydrophobicContact CB-CE2 4.38Å; M142-F174 HydrophobicContact CE-CZ 4.07Å; M142-F174 VanDerWaalsContact O-CE2 3.26Å; M142-F174 WeakPolarHBondContact O-CE2 3.43Å; M142-F174 WeakPolarHBondContact O-CZ 3.3Å
143S96.9Very high96.8Very high38 Ų3821.8 Ų21.827%0.26611%0.111SC..Hα-helixtrans-58.8-46.3179.5-174.70000112.1A141 L145 G146 E147 D171 H173A141-S143 PolarHBondContact O-N 2.84Å; S143-L145 VanDerWaalsContact C-N 3.3Å; S143-L145 PolarHBondContact O-N 3.36Å; S143-G146 PolarHBondContact O-N 3.26Å; S143-G146 VanDerWaalsContact O-N 3.13Å; S143-E147 PolarHBondContact O-N 2.86Å; S143-E147 VanDerWaalsContact O-N 3.14Å; S143-D171 WeakPolarHBondContact CB-OD2 3.32Å; S143-D171 PolarHBondContact OG-OD2 2.82Å; S143-H173 PolarHBondContact OG-CD2 2.99Å
144T97.5Very high96.8Very high39 Ų3922.2 Ų22.224%0.23911%0.113CC..Hα-helixtrans-69.1-26.8178.565.80000113.2A141 M142 E147 T148 Q192A141-T144 PolarHBondContact O-N 2.97Å; A141-T144 PolarHBondContact O-OG1 3.01Å; M142-T144 PolarHBondContact O-N 3.26Å; T144-E147 WeakPolarHBondContact O-CB 2.99Å; T144-E147 PolarHBondContact O-N 3.14Å; T144-T148 WeakPolarHBondContact O-CB 3.32Å; T144-T148 PolarHBondContact O-N 2.81Å; T144-T148 PolarHBondContact O-OG1 2.04Å; T144-Q192 VanDerWaalsContact CB-NE2 3.3Å; T144-Q192 PolarHBondContact OG1-NE2 3.34Å
145L98Very high96.9Very high1 Ų125.4 Ų25.41%0.00513%0.129CC..Hα-helixtrans-66.8-41.7170.6176.959.1000110.9L93 W102 V137 A141 M142 S143 E147 T148 L149 L205L93-L145 HydrophobicContact CD2-CD2 3.63Å; W102-L145 HydrophobicContact CD2-CD1 4.31Å; W102-L145 HydrophobicContact CD2-CD2 4.08Å; W102-L145 HydrophobicContact CE3-CD1 4.03Å; W102-L145 HydrophobicContact CE3-CD2 4.06Å; W102-L145 HydrophobicContact CG-CD2 4.33Å; W102-L145 HydrophobicContact CH2-CD1 3.65Å; W102-L145 HydrophobicContact CZ2-CD1 3.94Å; W102-L145 HydrophobicContact CZ3-CD1 3.72Å; V137-L145 HydrophobicContact CB-CD2 4.46Å; V137-L145 HydrophobicContact CG1-CD2 3.99Å; V137-L145 HydrophobicContact CG2-CD2 3.86Å; A141-L145 PolarHBondContact O-N 2.84Å; M142-L145 WeakPolarHBondContact O-CB 3.5Å; M142-L145 PolarHBondContact O-N 2.79Å; M142-L145 VanDerWaalsContact O-N 3.16Å; S143-L145 VanDerWaalsContact C-N 3.3Å; S143-L145 PolarHBondContact O-N 3.36Å; L145-E147 VanDerWaalsContact C-N 3.27Å; L145-E147 PolarHBondContact O-N 2.91Å; L145-T148 PolarHBondContact O-N 2.95Å; L145-T148 VanDerWaalsContact O-N 3.16Å; L145-L149 HydrophobicContact CD1-CD1 4.49Å; L145-L149 HydrophobicContact CD1-CG 4.25Å; L145-L149 HydrophobicContact CG-CD1 4.37Å; L145-L149 WeakPolarHBondContact O-CB 3.08Å; L145-L149 WeakPolarHBondContact O-CG 3.33Å; L145-L149 PolarHBondContact O-N 2.82Å; L145-L205 HydrophobicContact CD1-CD2 3.47Å; L145-L205 VanDerWaalsContact CD1-CD2 3.47Å
146G97.5Very high97Very high0 Ų027.1 Ų27.10%014%0.139CC..Hα-helixtrans-58.1-38.817200000112.6M142 S143 T150 F174M142-G146 PolarHBondContact O-N 3.37Å; S143-G146 PolarHBondContact O-N 3.26Å; S143-G146 VanDerWaalsContact O-N 3.13Å; G146-T150 PolarHBondContact O-N 2.85Å; G146-T150 VanDerWaalsContact O-N 3.16Å; G146-T150 PolarHBondContact O-OG1 2.8Å; G146-F174 VanDerWaalsContact CA-CE1 3.45Å
147E97.4Very high97.1Very high57 Ų5730.2 Ų30.227%0.26615%0.151SC..Hα-helixtrans-62.7-51.5172.3-170.6170.4-159.100111.1S143 T144 L145 L149 T150 Y151 H173S143-E147 PolarHBondContact O-N 2.86Å; S143-E147 VanDerWaalsContact O-N 3.14Å; T144-E147 WeakPolarHBondContact O-CB 2.99Å; T144-E147 PolarHBondContact O-N 3.14Å; L145-E147 VanDerWaalsContact C-N 3.27Å; L145-E147 PolarHBondContact O-N 2.91Å; E147-L149 VanDerWaalsContact C-N 3.27Å; E147-L149 PolarHBondContact O-N 3.37Å; E147-T150 VanDerWaalsContact O-CB 3.23Å; E147-T150 WeakPolarHBondContact O-CB 3.43Å; E147-T150 PolarHBondContact O-N 2.91Å; E147-Y151 HydrophobicContact CG-CE2 4.26Å; E147-Y151 WeakPolarHBondContact O-CD2 3.27Å; E147-H173 HydrophobicContact CB-CB 4.23Å; E147-H173 WeakPolarHBondContact CB-ND1 3.23Å; E147-H173 IonicContact OE1-CE1 3.53Å; E147-H173 IonicContact OE2-CE1 2.72Å; E147-H173 PolarHBondContact OE2-CE1 3.32Å; E147-H173 IonicContact OE2-ND1 2.6Å
148T98.2Very high97.3Very high0 Ų032.1 Ų32.10%016%0.16CC..Hα-helixtrans-59-37.5-178.1-60.10000112.6T144 L145 Y151 H190 Q192 L205 S207T144-T148 WeakPolarHBondContact O-CB 3.32Å; T144-T148 PolarHBondContact O-N 2.81Å; T144-T148 PolarHBondContact O-OG1 2.04Å; L145-T148 PolarHBondContact O-N 2.95Å; L145-T148 VanDerWaalsContact O-N 3.16Å; T148-Y151 PolarHBondContact O-N 2.59Å; T148-H190 PolarHBondContact OG1-CD2 2.73Å; T148-Q192 WeakPolarHBondContact OG1-CB 3.37Å; T148-L205 HydrophobicContact CG2-CB 3.77Å; T148-L205 HydrophobicContact CG2-CD2 3.65Å; T148-L205 HydrophobicContact CG2-CG 4.39Å; T148-S207 WeakPolarHBondContact CG2-OG 3.49Å; T148-S207 WeakPolarHBondContact O-CB 3.06Å; T148-S207 PolarHBondContact O-OG 3.29Å
149L98Very high97.4Very high0 Ų037.8 Ų37.80%018%0.181CC..Hα-helixtrans-70.3-31.3175.4-75.1178.2000112.5Y72 L93 W102 L145 E147 Y151 Q152 E153 P154 L177Y72-L149 HydrophobicContact CE1-CD1 4.29Å; L93-L149 HydrophobicContact CD1-CD1 3.45Å; L93-L149 VanDerWaalsContact CD1-CD1 3.45Å; L93-L149 HydrophobicContact CG-CD1 4.46Å; W102-L149 HydrophobicContact CZ2-CD2 3.89Å; L145-L149 HydrophobicContact CD1-CD1 4.49Å; L145-L149 HydrophobicContact CD1-CG 4.25Å; L145-L149 HydrophobicContact CG-CD1 4.37Å; L145-L149 WeakPolarHBondContact O-CB 3.08Å; L145-L149 WeakPolarHBondContact O-CG 3.33Å; L145-L149 PolarHBondContact O-N 2.82Å; E147-L149 VanDerWaalsContact C-N 3.27Å; E147-L149 PolarHBondContact O-N 3.37Å; L149-Y151 PolarHBondContact O-N 3.01Å; L149-Q152 CarbonylContact O-C 3.53Å; L149-Q152 WeakPolarHBondContact O-CA 3.09Å; L149-Q152 WeakPolarHBondContact O-CB 3.16Å; L149-Q152 PolarHBondContact O-N 2.87Å; L149-E153 PolarHBondContact O-N 3.32Å; L149-P154 WeakPolarHBondContact O-CD 3.18Å; L149-L177 HydrophobicContact CB-CD1 3.98Å; L149-L177 HydrophobicContact CB-CD2 3.81Å; L149-L177 HydrophobicContact CD1-CD2 4.02Å
150T97.6Very high97.5Very high12 Ų1235.7 Ų35.77%0.07417%0.17CC..Hα-helixtrans-58.3-35.2175-57.60000111.3G146 E147 Q152 E153G146-T150 PolarHBondContact O-N 2.85Å; G146-T150 VanDerWaalsContact O-N 3.16Å; G146-T150 PolarHBondContact O-OG1 2.8Å; E147-T150 VanDerWaalsContact O-CB 3.23Å; E147-T150 WeakPolarHBondContact O-CB 3.43Å; E147-T150 PolarHBondContact O-N 2.91Å; T150-Q152 VanDerWaalsContact C-N 3.31Å; T150-Q152 PolarHBondContact O-N 3.43Å; T150-E153 PolarHBondContact O-N 2.89Å; T150-E153 VanDerWaalsContact O-N 3.15Å
151Y98.1Very high97.6Very high22 Ų2229.8 Ų29.89%0.08614%0.143CC..Hα-helixtrans-67.7-29.8173.2-75.2-106.6000112.5E147 T148 L149 E153 L183 P187 H190 K208 S209E147-Y151 HydrophobicContact CG-CE2 4.26Å; E147-Y151 WeakPolarHBondContact O-CD2 3.27Å; T148-Y151 PolarHBondContact O-N 2.59Å; L149-Y151 PolarHBondContact O-N 3.01Å; Y151-E153 PolarHBondContact O-N 3.42Å; Y151-L183 HydrophobicContact CD1-CD1 3.32Å; Y151-L183 HydrophobicContact CD2-CD1 4.28Å; Y151-L183 HydrophobicContact CE1-CD1 3.27Å; Y151-L183 HydrophobicContact CE2-CD1 4.24Å; Y151-L183 HydrophobicContact CE2-CD2 4.4Å; Y151-L183 HydrophobicContact CG-CD1 3.84Å; Y151-P187 WeakPolarHBondContact CE1-O 3.49Å; Y151-H190 HydrophobicContact CD1-CB 3.55Å; Y151-H190 HydrophobicContact CD2-CB 3.59Å; Y151-H190 AromaticContact CD2-CG 3.97Å; Y151-H190 HydrophobicContact CE1-CB 3.63Å; Y151-H190 HydrophobicContact CE2-CB 3.68Å; Y151-H190 AromaticContact CE2-CG 3.77Å; Y151-H190 AromaticContact CE2-ND1 3.86Å; Y151-H190 HydrophobicContact CG-CB 3.55Å; Y151-H190 AromaticContact CZ-ND1 3.92Å; Y151-K208 CarbonylContact O-C 3.54Å; Y151-S209 WeakPolarHBondContact O-CA 2.99Å; Y151-S209 PolarHBondContact O-N 3.45Å; Y151-S209 VanDerWaalsContact O-N 3.11Å
152Q97.9Very high97.6Very high1 Ų129.6 Ų29.61%0.00514%0.142CC..Hα-helixtrans-78.2-8.5175.6-54.6-174.315.800112.2S87 L149 T150 P154 S207 S301S87-Q152 VanDerWaalsContact CB-O 3.27Å; S87-Q152 WeakPolarHBondContact CB-O 3.04Å; S87-Q152 PolarHBondContact OG-O 3.11Å; L149-Q152 CarbonylContact O-C 3.53Å; L149-Q152 WeakPolarHBondContact O-CA 3.09Å; L149-Q152 WeakPolarHBondContact O-CB 3.16Å; L149-Q152 PolarHBondContact O-N 2.87Å; T150-Q152 VanDerWaalsContact C-N 3.31Å; T150-Q152 PolarHBondContact O-N 3.43Å; Q152-P154 VanDerWaalsContact C-CD 3.45Å; Q152-P154 VanDerWaalsContact C-N 3.33Å; Q152-S207 VanDerWaalsContact CG-OG 3.23Å; Q152-S207 WeakPolarHBondContact CG-OG 3.19Å; Q152-S207 PolarHBondContact NE2-OG 3.32Å; Q152-S301 WeakPolarHBondContact O-CB 3.22Å; Q152-S301 PolarHBondContact O-OG 3.21Å
153E97.3Very high97.6Very high21 Ų2134.6 Ų34.610%0.09817%0.168CC..  trans45.347178.5-56.5-179.8-15600114.5S87 L149 T150 Y151 K182 S209 R210S87-E153 WeakPolarHBondContact CB-O 3.43Å; L149-E153 PolarHBondContact O-N 3.32Å; T150-E153 PolarHBondContact O-N 2.89Å; T150-E153 VanDerWaalsContact O-N 3.15Å; Y151-E153 PolarHBondContact O-N 3.42Å; E153-K182 HydrophobicContact CB-CD 4.42Å; E153-K182 HydrophobicContact CG-CD 3.99Å; E153-K182 WeakPolarHBondContact OE2-CD 3.19Å; E153-K182 WeakPolarHBondContact OE2-CE 3.4Å; E153-K182 IonicContact OE2-NZ 2.68Å; E153-K182 PolarHBondContact OE2-NZ 3.06Å; E153-S209 VanDerWaalsContact OE1-CB 3.3Å; E153-S209 WeakPolarHBondContact OE1-CB 2.92Å; E153-R210 WeakPolarHBondContact OE1-CB 3.32Å; E153-R210 PolarHBondContact OE1-N 3.1Å
154P97.7Very high97.5Very high8 Ų841.9 Ų41.95%0.05220%0.195CC..  trans-67.5155.3-174.133.1-39.1000111.9Y72 L149 Q152 V156 L177Y72-P154 HydrophobicContact CD2-CB 3.42Å; Y72-P154 VanDerWaalsContact CD2-CB 3.42Å; Y72-P154 HydrophobicContact CD2-CG 4.25Å; Y72-P154 HydrophobicContact CE2-CB 4.11Å; Y72-P154 HydrophobicContact CG-CB 3.71Å; Y72-P154 HydrophobicContact CG-CG 4.22Å; L149-P154 WeakPolarHBondContact O-CD 3.18Å; Q152-P154 VanDerWaalsContact C-CD 3.45Å; Q152-P154 VanDerWaalsContact C-N 3.33Å; P154-V156 PolarHBondContact O-N 3.37Å; P154-L177 HydrophobicContact CG-CD1 3.6Å
155M97.4Very high97.2Very high67 Ų6741 Ų4133%0.3319%0.191SC..  trans-85.695.1174.9-70.9-63.8-61.600110.1Y72 S73 N74 E86 Y157Y72-M155 CarbonylContact C-O 3.19Å; Y72-M155 WeakPolarHBondContact CA-O 3.33Å; Y72-M155 WeakPolarHBondContact CB-O 3.36Å; S73-M155 PolarHBondContact N-O 3.27Å; N74-M155 HydrophobicContact CB-CG 4.45Å; E86-M155 HydrophobicContact CB-CG 3.95Å; E86-M155 HydrophobicContact CB-SD 4.36Å; E86-M155 HydrophobicContact CG-CG 4.31Å; E86-M155 HydrophobicContact CG-SD 4.17Å; M155-Y157 PolarHBondContact O-N 3.36Å
156V97.9Very high97Very high37 Ų3744 Ų4422%0.22421%0.21CC..EExtended strand (participates in β ladder)trans-68.2119175.9179.60000109.4I70 P154 W159I70-V156 HydrophobicContact CG2-CG1 4.01Å; I70-V156 HydrophobicContact CG2-CG2 3.97Å; P154-V156 PolarHBondContact O-N 3.37Å; V156-W159 HydrophobicContact CG1-CB 4.21Å
157Y97.8Very high96.8Very high67 Ų6746.6 Ų46.626%0.26322%0.224SC..EExtended strand (participates in β ladder)trans-107.9-16177.571.2-92.5000112.8A71 A76 P77 P111 M113 M155A71-Y157 VanDerWaalsContact C-CE1 3.43Å; A71-Y157 HydrophobicContact CB-CD1 4.42Å; A71-Y157 HydrophobicContact CB-CE1 3.62Å; A71-Y157 HydrophobicContact CB-CE2 4.05Å; A71-Y157 WeakPolarHBondContact CB-OH 3.32Å; A71-Y157 WeakPolarHBondContact O-CD1 3.49Å; A71-Y157 PolarHBondContact O-N 3.38Å; A76-Y157 HydrophobicContact CB-CD1 3.82Å; A76-Y157 HydrophobicContact CB-CD2 4.16Å; A76-Y157 HydrophobicContact CB-CE1 4.45Å; A76-Y157 HydrophobicContact CB-CG 3.65Å; P77-Y157 HydrophobicContact CG-CE2 4.19Å; P111-Y157 VanDerWaalsContact CD-OH 3.23Å; P111-Y157 WeakPolarHBondContact CD-OH 3.49Å; P111-Y157 PolarHBondContact O-OH 3.16Å; M113-Y157 HydrophobicContact CB-CE2 4.2Å; M113-Y157 HydrophobicContact CG-CE2 3.71Å; M155-Y157 PolarHBondContact O-N 3.36Å
158F98.3Very high96.6Very high41 Ų4143.9 Ų43.918%0.1821%0.211CC..EExtended strand (participates in β ladder)trans-147.2137175.4179-88.3000109.3K64 I69 A71 M113 K160K64-F158 HydrophobicContact CD-CE1 4.34Å; K64-F158 HydrophobicContact CD-CZ 3.82Å; I69-F158 HydrophobicContact CB-CE1 4.11Å; I69-F158 HydrophobicContact CG2-CD1 3.96Å; I69-F158 HydrophobicContact CG2-CE1 3.83Å; A71-F158 HydrophobicContact CB-CB 4.21Å; A71-F158 PolarHBondContact N-O 2.85Å; A71-F158 PolarHBondContact O-N 2.72Å; M113-F158 HydrophobicContact CB-CB 3.79Å; M113-F158 HydrophobicContact CB-CD1 3.82Å; M113-F158 HydrophobicContact CB-CD2 3.55Å; M113-F158 HydrophobicContact CB-CE1 4.3Å; M113-F158 HydrophobicContact CB-CE2 4.05Å; M113-F158 HydrophobicContact CB-CG 3.42Å; M113-F158 VanDerWaalsContact CB-CG 3.42Å; M113-F158 HydrophobicContact CB-CZ 4.41Å; M113-F158 HydrophobicContact CE-CD1 3.74Å; M113-F158 HydrophobicContact CE-CE1 3.68Å; M113-F158 HydrophobicContact CE-CG 4.5Å; M113-F158 HydrophobicContact CE-CZ 4.37Å; M113-F158 HydrophobicContact CG-CB 3.83Å; M113-F158 HydrophobicContact CG-CD1 3.88Å; M113-F158 HydrophobicContact CG-CD2 4.42Å; M113-F158 HydrophobicContact CG-CG 3.79Å; F158-K160 HydrophobicContact CE1-CB 4.03Å; F158-K160 HydrophobicContact CZ-CB 4.05Å; F158-K160 HydrophobicContact CZ-CD 4.49Å
159W97.9Very high96.3Very high124 Ų12446.8 Ų46.847%0.4723%0.231SC..EExtended strand (participates in β ladder)trans-148.7154.116670.2-84.2000110.2I69 I70 V156 L168 I178I69-W159 CarbonylContact O-C 3.59Å; I69-W159 WeakPolarHBondContact O-CA 3.49Å; I70-W159 HydrophobicContact CG1-CB 4.28Å; V156-W159 HydrophobicContact CG1-CB 4.21Å; W159-L168 HydrophobicContact CB-CD1 4.48Å; W159-L168 HydrophobicContact CE3-CD1 4.08Å; W159-I178 HydrophobicContact CB-CD1 4.23Å; W159-I178 HydrophobicContact CB-CG1 4.26Å; W159-I178 HydrophobicContact CD2-CD1 4.04Å; W159-I178 HydrophobicContact CD2-CG1 4.49Å; W159-I178 HydrophobicContact CD2-CG2 3.8Å; W159-I178 HydrophobicContact CE3-CD1 3.92Å; W159-I178 HydrophobicContact CG-CD1 4.19Å; W159-I178 HydrophobicContact CG-CG1 4.23Å; W159-I178 HydrophobicContact CG-CG2 3.8Å; W159-I178 HydrophobicContact CZ2-CG2 4.3Å
160K97.5Very high96Very high52 Ų5250 Ų5023%0.22627%0.265CS..EExtended strand (participates in β ladder)trans-158.8129.5177.3-179.2171.5167.2720110.4K64 D65 N68 I69 F158 L168K64-K160 VanDerWaalsContact C-CE 3.48Å; K64-K160 HydrophobicContact CB-CD 4.01Å; K64-K160 VanDerWaalsContact O-CE 3.27Å; K64-K160 WeakPolarHBondContact O-CE 3.24Å; D65-K160 VanDerWaalsContact CA-CE 3.46Å; D65-K160 WeakPolarHBondContact OD1-CE 3.5Å; D65-K160 IonicContact OD1-NZ 2.67Å; D65-K160 PolarHBondContact OD1-NZ 3.4Å; N68-K160 CarbonylContact C-O 3.49Å; N68-K160 WeakPolarHBondContact CA-O 3.47Å; I69-K160 PolarHBondContact N-O 2.73Å; I69-K160 PolarHBondContact O-N 3.06Å; F158-K160 HydrophobicContact CE1-CB 4.03Å; F158-K160 HydrophobicContact CZ-CB 4.05Å; F158-K160 HydrophobicContact CZ-CD 4.49Å; K160-L168 WeakPolarHBondContact O-CD1 3.43Å
161D97.3Very high95.9Very high25 Ų2551 Ų5113%0.13427%0.27CS..  trans-74.4147.9167-89.4-49.7000110.9N68 P166 L167 L168 S169N68-D161 PolarHBondContact OD1-OD1 3.12Å; D161-P166 HydrophobicContact CB-CB 3.7Å; D161-P166 VanDerWaalsContact OD1-CA 3.25Å; D161-P166 WeakPolarHBondContact OD1-CA 3.26Å; D161-L167 PolarHBondContact OD1-N 3.06Å; D161-L168 WeakPolarHBondContact OD1-CA 3.41Å; D161-L168 WeakPolarHBondContact OD1-CB 3.06Å; D161-L168 WeakPolarHBondContact OD1-CG 3.47Å; D161-L168 PolarHBondContact OD1-N 3.14Å; D161-S169 PolarHBondContact OD1-N 3.13Å; D161-S169 WeakPolarHBondContact OD2-CB 3.37Å; D161-S169 PolarHBondContact OD2-N 2.88Å; D161-S169 PolarHBondContact OD2-OG 2.98Å
162A96.8Very high95.8Very high3 Ų356.4 Ų56.43%0.02529%0.294CS..  trans-67.2136.6166.400000109.7N66 K67 N68 K164 S165N66-A162 VanDerWaalsContact C-CB 3.44Å; N66-A162 WeakPolarHBondContact O-CB 3.43Å; K67-A162 PolarHBondContact O-N 3.21Å; N68-A162 PolarHBondContact OD1-N 3.43Å; A162-K164 PolarHBondContact O-N 3.41Å; A162-S165 WeakPolarHBondContact CB-O 3.31Å; A162-S165 CarbonylContact O-C 3.42Å; A162-S165 PolarHBondContact O-N 3.4Å
163N96.2Very high95.8Very high111 Ų11157.2 Ų57.259%0.59430%0.297SS*.SBendtrans-60.4-33.3-177.2-69.4-6.2000112.7D65D65-N163 WeakPolarHBondContact O-CB 3.29Å; D65-N163 PolarHBondContact O-N 3.07Å
164K94.4Very high95.8Very high191 Ų19156.3 Ų56.383%0.8329%0.293SS*.SBendtrans-91.7-24.5-178.9-67.3-174.5179.3179.30113.8A162A162-K164 PolarHBondContact O-N 3.41Å
165S92.9Very high95.7Very high20 Ų2060.2 Ų60.214%0.1431%0.311CS..  trans-146.382.7-175.4-171.10000110.6N68 D97 A162 L167N68-S165 PolarHBondContact ND2-O 3.24Å; N68-S165 PolarHBondContact OD1-O 3.27Å; D97-S165 WeakPolarHBondContact OD1-CB 3.15Å; D97-S165 PolarHBondContact OD1-OG 2.81Å; A162-S165 WeakPolarHBondContact CB-O 3.31Å; A162-S165 CarbonylContact O-C 3.42Å; A162-S165 PolarHBondContact O-N 3.4Å; S165-L167 PolarHBondContact O-N 3.38Å
166P92.3Very high95.6Very high65 Ų6562.2 Ų62.242%0.42232%0.315SS..  trans-77.681.9-175.832.1-35.9000111.3D161 G170D161-P166 HydrophobicContact CB-CB 3.7Å; D161-P166 VanDerWaalsContact OD1-CA 3.25Å; D161-P166 WeakPolarHBondContact OD1-CA 3.26Å; P166-G170 PolarHBondContact O-N 3.16Å
167L93.5Very high95.6Very high55 Ų5560.7 Ų60.729%0.28831%0.305SS..Hα-helixtrans-84.6-14.6-173.8-61.2177.4000113.5N68 W95 E96 D161 S165 D171N68-L167 PolarHBondContact OD1-N 3.46Å; W95-L167 HydrophobicContact CZ2-CB 4.37Å; W95-L167 VanDerWaalsContact NE1-CD1 3.32Å; E96-L167 VanDerWaalsContact O-CD1 3.24Å; E96-L167 WeakPolarHBondContact O-CD1 3.49Å; D161-L167 PolarHBondContact OD1-N 3.06Å; S165-L167 PolarHBondContact O-N 3.38Å; L167-D171 WeakPolarHBondContact O-CB 3.05Å; L167-D171 PolarHBondContact O-N 3.24Å
168L94.2Very high95.6Very high0 Ų058.7 Ų58.70%030%0.299CS..Hα-helixtrans-76.7-50.6176.9-55.6180000111.4N68 I69 I70 W95 W159 K160 D161 F174 H175 I178N68-L168 HydrophobicContact CB-CD2 4.12Å; N68-L168 HydrophobicContact CB-CG 3.99Å; I69-L168 VanDerWaalsContact O-CD1 3.32Å; I69-L168 WeakPolarHBondContact O-CD1 3.45Å; I70-L168 HydrophobicContact CD1-CD2 3.75Å; I70-L168 HydrophobicContact CG1-CD1 3.93Å; I70-L168 HydrophobicContact CG1-CD2 3.83Å; W95-L168 HydrophobicContact CH2-CD2 2.99Å; W95-L168 HydrophobicContact CH2-CG 4.35Å; W95-L168 HydrophobicContact CZ2-CD2 3.42Å; W95-L168 VanDerWaalsContact CZ2-CD2 3.42Å; W95-L168 HydrophobicContact CZ3-CD2 3.7Å; W159-L168 HydrophobicContact CB-CD1 4.48Å; W159-L168 HydrophobicContact CE3-CD1 4.08Å; K160-L168 WeakPolarHBondContact O-CD1 3.43Å; D161-L168 WeakPolarHBondContact OD1-CA 3.41Å; D161-L168 WeakPolarHBondContact OD1-CB 3.06Å; D161-L168 WeakPolarHBondContact OD1-CG 3.47Å; D161-L168 PolarHBondContact OD1-N 3.14Å; L168-F174 HydrophobicContact CB-CB 4.48Å; L168-F174 HydrophobicContact CD2-CB 4.26Å; L168-F174 HydrophobicContact CD2-CD1 4.43Å; L168-F174 HydrophobicContact CD2-CG 4.19Å; L168-F174 WeakPolarHBondContact O-CB 3.3Å; L168-H175 PolarHBondContact O-N 3.21Å; L168-I178 HydrophobicContact CB-CD1 3.72Å; L168-I178 HydrophobicContact CD1-CD1 4.03Å; L168-I178 HydrophobicContact CG-CD1 4.35Å
169S90.2Very high95.5Very high60 Ų6062.9 Ų62.942%0.4232%0.319SS..Hα-helixtrans-74.1-30-179.4510000112.5D161D161-S169 PolarHBondContact OD1-N 3.13Å; D161-S169 WeakPolarHBondContact OD2-CB 3.37Å; D161-S169 PolarHBondContact OD2-N 2.88Å; D161-S169 PolarHBondContact OD2-OG 2.98Å
170G91.8Very high95.4Very high69 Ų6958.7 Ų58.771%0.71131%0.314SS*.Hα-helixtrans-73.8-2517500000114.4P166P166-G170 PolarHBondContact O-N 3.16Å
171D96.2Very high95.2Very high32 Ų3261 Ų6117%0.17133%0.326CS..SBendtrans-92.8123.2178.8-177.8-79.3000111.6S143 L167 H173 F174 H175S143-D171 WeakPolarHBondContact CB-OD2 3.32Å; S143-D171 PolarHBondContact OG-OD2 2.82Å; L167-D171 WeakPolarHBondContact O-CB 3.05Å; L167-D171 PolarHBondContact O-N 3.24Å; D171-H173 VanDerWaalsContact C-N 3.25Å; D171-H173 PolarHBondContact O-N 2.91Å; D171-H173 VanDerWaalsContact OD1-CA 3.3Å; D171-H173 WeakPolarHBondContact OD1-CA 3.44Å; D171-H173 VanDerWaalsContact OD1-CB 3.28Å; D171-H173 WeakPolarHBondContact OD1-CB 3.49Å; D171-H173 PolarHBondContact OD1-N 2.91Å; D171-F174 HydrophobicContact CB-CB 4.27Å; D171-F174 HydrophobicContact CB-CD2 3.88Å; D171-F174 PolarHBondContact O-N 3.33Å; D171-F174 PolarHBondContact OD1-N 2.81Å; D171-H175 VanDerWaalsContact O-CB 3.31Å; D171-H175 WeakPolarHBondContact O-CB 3.26Å; D171-H175 PolarHBondContact O-N 3.28Å
172K96.5Very high95.1Very high135 Ų13564.6 Ų64.659%0.58734%0.34SS*.Hα-helixtrans-60.4-31.5-177.871.8-173.8-178.8-173.50113.4R176K172-R176 WeakPolarHBondContact O-CD 3.12Å; K172-R176 WeakPolarHBondContact O-CG 3.36Å; K172-R176 PolarHBondContact O-N 3.29Å
173H97.1Very high95Very high18 Ų1866 Ų668%0.08335%0.347CS..Hα-helixtrans-78.8-43.7-177.8-63.5-77.2000110.8S143 E147 D171 R176 L177S143-H173 PolarHBondContact OG-CD2 2.99Å; E147-H173 HydrophobicContact CB-CB 4.23Å; E147-H173 WeakPolarHBondContact CB-ND1 3.23Å; E147-H173 IonicContact OE1-CE1 3.53Å; E147-H173 IonicContact OE2-CE1 2.72Å; E147-H173 PolarHBondContact OE2-CE1 3.32Å; E147-H173 IonicContact OE2-ND1 2.6Å; D171-H173 VanDerWaalsContact C-N 3.25Å; D171-H173 PolarHBondContact O-N 2.91Å; D171-H173 VanDerWaalsContact OD1-CA 3.3Å; D171-H173 WeakPolarHBondContact OD1-CA 3.44Å; D171-H173 VanDerWaalsContact OD1-CB 3.28Å; D171-H173 WeakPolarHBondContact OD1-CB 3.49Å; D171-H173 PolarHBondContact OD1-N 2.91Å; H173-R176 PolarHBondContact O-N 3.37Å; H173-L177 PolarHBondContact O-N 2.75Å
174F97.7Very high94.7Very high2 Ų263.5 Ų63.51%0.00934%0.342CS..Hα-helixtrans-66.2-38.9173.7-74.1-59.6000112.7I70 L93 W95 M142 G146 L168 D171 R176 L177 I178I70-F174 HydrophobicContact CD1-CD1 3.55Å; I70-F174 HydrophobicContact CD1-CE1 4.17Å; I70-F174 HydrophobicContact CD1-CG 4.37Å; L93-F174 HydrophobicContact CD1-CE1 3.94Å; W95-F174 AromaticContact CH2-CD1 3.88Å; W95-F174 HydrophobicContact CH2-CD1 3.88Å; W95-F174 AromaticContact CH2-CD2 3.72Å; W95-F174 HydrophobicContact CH2-CD2 3.72Å; W95-F174 AromaticContact CH2-CE1 3.58Å; W95-F174 HydrophobicContact CH2-CE1 3.58Å; W95-F174 AromaticContact CH2-CE2 3.4Å; W95-F174 HydrophobicContact CH2-CE2 3.4Å; W95-F174 VanDerWaalsContact CH2-CE2 3.4Å; W95-F174 AromaticContact CH2-CG 3.95Å; W95-F174 HydrophobicContact CH2-CG 3.95Å; W95-F174 AromaticContact CH2-CZ 3.32Å; W95-F174 HydrophobicContact CH2-CZ 3.32Å; W95-F174 AromaticContact CZ2-CD2 3.67Å; W95-F174 HydrophobicContact CZ2-CD2 3.67Å; W95-F174 HydrophobicContact CZ2-CE1 4.42Å; W95-F174 AromaticContact CZ2-CE2 3.39Å; W95-F174 HydrophobicContact CZ2-CE2 3.39Å; W95-F174 HydrophobicContact CZ2-CG 4.3Å; W95-F174 AromaticContact CZ2-CZ 3.81Å; W95-F174 HydrophobicContact CZ2-CZ 3.81Å; W95-F174 HydrophobicContact CZ3-CE1 4.26Å; W95-F174 HydrophobicContact CZ3-CZ 4.1Å; M142-F174 HydrophobicContact CB-CE2 4.38Å; M142-F174 HydrophobicContact CE-CZ 4.07Å; M142-F174 VanDerWaalsContact O-CE2 3.26Å; M142-F174 WeakPolarHBondContact O-CE2 3.43Å; M142-F174 WeakPolarHBondContact O-CZ 3.3Å; G146-F174 VanDerWaalsContact CA-CE1 3.45Å; L168-F174 HydrophobicContact CB-CB 4.48Å; L168-F174 HydrophobicContact CD2-CB 4.26Å; L168-F174 HydrophobicContact CD2-CD1 4.43Å; L168-F174 HydrophobicContact CD2-CG 4.19Å; L168-F174 WeakPolarHBondContact O-CB 3.3Å; D171-F174 HydrophobicContact CB-CB 4.27Å; D171-F174 HydrophobicContact CB-CD2 3.88Å; D171-F174 PolarHBondContact O-N 3.33Å; D171-F174 PolarHBondContact OD1-N 2.81Å; F174-R176 VanDerWaalsContact C-N 3.31Å; F174-R176 PolarHBondContact O-N 3.04Å; F174-L177 HydrophobicContact CD1-CD2 4.15Å; F174-L177 HydrophobicContact CE1-CD2 4.49Å; F174-L177 WeakPolarHBondContact O-CB 3.42Å; F174-L177 PolarHBondContact O-N 2.52Å; F174-I178 WeakPolarHBondContact O-CG1 3.42Å; F174-I178 PolarHBondContact O-N 3.35Å
175H95.9Very high94.7Very high90 Ų9063.7 Ų63.742%0.41734%0.339SS..Hα-helixtrans-56.9-46.2173.2-173.379.3000111.5L168 D171 L177 I178 Q179L168-H175 PolarHBondContact O-N 3.21Å; D171-H175 VanDerWaalsContact O-CB 3.31Å; D171-H175 WeakPolarHBondContact O-CB 3.26Å; D171-H175 PolarHBondContact O-N 3.28Å; H175-L177 PolarHBondContact O-N 2.86Å; H175-I178 PolarHBondContact O-N 2.85Å; H175-Q179 WeakPolarHBondContact O-CB 3.24Å; H175-Q179 VanDerWaalsContact O-CG 3.24Å; H175-Q179 WeakPolarHBondContact O-CG 3.28Å; H175-Q179 PolarHBondContact O-N 2.98Å
176R96Very high94.8Very high110 Ų11067.1 Ų67.142%0.41536%0.362SS..Hα-helixtrans-63.4-40.4176.6-70.9173.6177.1177-0.3112.9K172 H173 F174 Q179 G180 Q181K172-R176 WeakPolarHBondContact O-CD 3.12Å; K172-R176 WeakPolarHBondContact O-CG 3.36Å; K172-R176 PolarHBondContact O-N 3.29Å; H173-R176 PolarHBondContact O-N 3.37Å; F174-R176 VanDerWaalsContact C-N 3.31Å; F174-R176 PolarHBondContact O-N 3.04Å; R176-Q179 PolarHBondContact O-N 2.88Å; R176-G180 PolarHBondContact O-N 3.26Å; R176-Q181 HydrophobicContact CB-CB 4.13Å; R176-Q181 WeakPolarHBondContact O-CB 3.3Å; R176-Q181 PolarHBondContact O-N 2.85Å
177L97.6Very high95Very high4 Ų467.9 Ų67.92%0.02137%0.368CS..Hα-helixtrans-60.7-48.8177-179.762.3000111.4I70 L149 P154 H173 F174 H175 Q179 G180I70-L177 HydrophobicContact CD1-CD2 4.07Å; L149-L177 HydrophobicContact CB-CD1 3.98Å; L149-L177 HydrophobicContact CB-CD2 3.81Å; L149-L177 HydrophobicContact CD1-CD2 4.02Å; P154-L177 HydrophobicContact CG-CD1 3.6Å; H173-L177 PolarHBondContact O-N 2.75Å; F174-L177 HydrophobicContact CD1-CD2 4.15Å; F174-L177 HydrophobicContact CE1-CD2 4.49Å; F174-L177 WeakPolarHBondContact O-CB 3.42Å; F174-L177 PolarHBondContact O-N 2.52Å; H175-L177 PolarHBondContact O-N 2.86Å; L177-Q179 VanDerWaalsContact C-N 3.33Å; L177-Q179 PolarHBondContact O-N 2.88Å; L177-G180 PolarHBondContact O-N 2.95Å
178I97.3Very high95.2Very high25 Ų2567.9 Ų67.913%0.12837%0.365CS..Hα-helixtrans-64.2-39179.7-69.9164.4000111.4I70 W159 L168 F174 H175 G180I70-I178 HydrophobicContact CD1-CD1 4.02Å; I70-I178 HydrophobicContact CD1-CG1 3.91Å; I70-I178 HydrophobicContact CG1-CD1 4.26Å; I70-I178 HydrophobicContact CG1-CG1 4.24Å; W159-I178 HydrophobicContact CB-CD1 4.23Å; W159-I178 HydrophobicContact CB-CG1 4.26Å; W159-I178 HydrophobicContact CD2-CD1 4.04Å; W159-I178 HydrophobicContact CD2-CG1 4.49Å; W159-I178 HydrophobicContact CD2-CG2 3.8Å; W159-I178 HydrophobicContact CE3-CD1 3.92Å; W159-I178 HydrophobicContact CG-CD1 4.19Å; W159-I178 HydrophobicContact CG-CG1 4.23Å; W159-I178 HydrophobicContact CG-CG2 3.8Å; W159-I178 HydrophobicContact CZ2-CG2 4.3Å; L168-I178 HydrophobicContact CB-CD1 3.72Å; L168-I178 HydrophobicContact CD1-CD1 4.03Å; L168-I178 HydrophobicContact CG-CD1 4.35Å; F174-I178 WeakPolarHBondContact O-CG1 3.42Å; F174-I178 PolarHBondContact O-N 3.35Å; H175-I178 PolarHBondContact O-N 2.85Å; I178-G180 PolarHBondContact O-N 3.37Å
179Q95.7Very high95.4Very high129 Ų12969.4 Ų69.460%0.60338%0.375SS*.THydrogen-bonded Turntrans-72.4-2.7175.1-65.4-60.8-31.700113.3H175 R176 L177 Q181H175-Q179 WeakPolarHBondContact O-CB 3.24Å; H175-Q179 VanDerWaalsContact O-CG 3.24Å; H175-Q179 WeakPolarHBondContact O-CG 3.28Å; H175-Q179 PolarHBondContact O-N 2.98Å; R176-Q179 PolarHBondContact O-N 2.88Å; L177-Q179 VanDerWaalsContact C-N 3.33Å; L177-Q179 PolarHBondContact O-N 2.88Å; Q179-Q181 PolarHBondContact O-N 2.85Å
180G95.3Very high95.8Very high36 Ų3668.2 Ų68.237%0.37136%0.363SS..THydrogen-bonded Turntrans6428-178.300000113.1R176 L177 I178 K182R176-G180 PolarHBondContact O-N 3.26Å; L177-G180 PolarHBondContact O-N 2.95Å; I178-G180 PolarHBondContact O-N 3.37Å; G180-K182 PolarHBondContact O-N 2.62Å
181Q95.2Very high96.1Very high102 Ų10268.1 Ų68.148%0.47734%0.341SS..PPolyproline II helixtrans-61.4127.9-175.5-170.6-18042.900110.7R176 Q179R176-Q181 HydrophobicContact CB-CB 4.13Å; R176-Q181 WeakPolarHBondContact O-CB 3.3Å; R176-Q181 PolarHBondContact O-N 2.85Å; Q179-Q181 PolarHBondContact O-N 2.85Å
182K94.2Very high96.2Very high100 Ų10068.7 Ų68.744%0.43534%0.343SS..PPolyproline II helixtrans-93.3145.9177.4-52.5-58.7-173.9165.60110.7E153 G180 A184E153-K182 HydrophobicContact CB-CD 4.42Å; E153-K182 HydrophobicContact CG-CD 3.99Å; E153-K182 WeakPolarHBondContact OE2-CD 3.19Å; E153-K182 WeakPolarHBondContact OE2-CE 3.4Å; E153-K182 IonicContact OE2-NZ 2.68Å; E153-K182 PolarHBondContact OE2-NZ 3.06Å; G180-K182 PolarHBondContact O-N 2.62Å; K182-A184 PolarHBondContact O-N 2.77Å
183L93.9Very high96.3Very high33 Ų3366.7 Ų66.717%0.17334%0.335CS..PPolyproline II helixtrans-65.5125.8177.3-62.7175.7000110.9Y151 F188 K211Y151-L183 HydrophobicContact CD1-CD1 3.32Å; Y151-L183 HydrophobicContact CD2-CD1 4.28Å; Y151-L183 HydrophobicContact CE1-CD1 3.27Å; Y151-L183 HydrophobicContact CE2-CD1 4.24Å; Y151-L183 HydrophobicContact CE2-CD2 4.4Å; Y151-L183 HydrophobicContact CG-CD1 3.84Å; L183-F188 HydrophobicContact CB-CD1 4.37Å; L183-K211 WeakPolarHBondContact O-CD 3.42Å; L183-K211 WeakPolarHBondContact O-CE 3.19Å; L183-K211 PolarHBondContact O-NZ 2.91Å
184A91.8Very high96.3Very high58 Ų5866.5 Ų66.548%0.47933%0.334SS..  trans-76.6-44.2176.800000111.5K182 K211K182-A184 PolarHBondContact O-N 2.77Å; A184-K211 PolarHBondContact O-NZ 2.95Å
185Y93.9Very high96.2Very high195 Ų19570.6 Ų70.677%0.76536%0.356SS*.SBendtrans-127.2162.9-169.9-51.4-73.4000111.8F188Y185-F188 VanDerWaalsContact O-CE1 3.3Å; Y185-F188 WeakPolarHBondContact O-CE1 3.13Å
186S94.8Very high96Very high91 Ų9166.3 Ų66.364%0.63634%0.336SS*.SBendtrans-67.5158.517356.30000111.2
187P96.6Very high95.5Very high82 Ų8262.3 Ų62.353%0.53232%0.324SS..  cis-69.5145.21.330.5-35.5000112.9Y151Y151-P187 WeakPolarHBondContact CE1-O 3.49Å
188F98Very high94.9Very high54 Ų5466.4 Ų66.424%0.23734%0.341CS..  trans-97.47175.2-61.1-50.7000112.7L183 Y185 K208 S209 K211L183-F188 HydrophobicContact CB-CD1 4.37Å; Y185-F188 VanDerWaalsContact O-CE1 3.3Å; Y185-F188 WeakPolarHBondContact O-CE1 3.13Å; F188-K208 WeakPolarHBondContact O-CA 3.42Å; F188-S209 WeakPolarHBondContact CB-OG 3.31Å; F188-S209 PolarHBondContact O-N 2.85Å; F188-S209 PolarHBondContact O-OG 2.82Å; F188-K211 HydrophobicContact CD1-CB 3.64Å; F188-K211 HydrophobicContact CD1-CD 4.23Å; F188-K211 HydrophobicContact CD2-CB 3.97Å; F188-K211 HydrophobicContact CE1-CB 3.69Å; F188-K211 HydrophobicContact CE1-CD 3.53Å; F188-K211 HydrophobicContact CE1-CG 4.28Å; F188-K211 HydrophobicContact CE2-CB 4.02Å; F188-K211 HydrophobicContact CG-CB 3.79Å; F188-K211 HydrophobicContact CZ-CB 3.89Å; F188-K211 HydrophobicContact CZ-CD 3.81Å; F188-K211 HydrophobicContact CZ-CG 4.5Å
189T98.5Very high94.3Very high32 Ų3267.3 Ų67.320%0.19636%0.357CS..EExtended strand (participates in β ladder)trans-126.3149.5173.853.40000109.3S207 K208 L214 Y220T189-S207 CarbonylContact C-O 3.45Å; T189-S207 VanDerWaalsContact CA-O 3.24Å; T189-S207 WeakPolarHBondContact CA-O 3.42Å; T189-K208 HydrophobicContact CG2-CB 3.97Å; T189-L214 HydrophobicContact CG2-CD2 3.84Å; T189-Y220 VanDerWaalsContact CB-CZ 3.46Å; T189-Y220 HydrophobicContact CG2-CD1 4.14Å; T189-Y220 HydrophobicContact CG2-CD2 3.99Å; T189-Y220 HydrophobicContact CG2-CE1 4.29Å; T189-Y220 HydrophobicContact CG2-CE2 4.16Å; T189-Y220 HydrophobicContact CG2-CG 4Å; T189-Y220 WeakPolarHBondContact OG1-CE2 3.27Å
190H98.4Very high94Very high36 Ų3667 Ų6717%0.16735%0.354CS..EExtended strand (participates in β ladder)trans-141.7136-179.7-168.177.4000110.1T148 Y151 S207 Y220T148-H190 PolarHBondContact OG1-CD2 2.73Å; Y151-H190 HydrophobicContact CD1-CB 3.55Å; Y151-H190 HydrophobicContact CD2-CB 3.59Å; Y151-H190 AromaticContact CD2-CG 3.97Å; Y151-H190 HydrophobicContact CE1-CB 3.63Å; Y151-H190 HydrophobicContact CE2-CB 3.68Å; Y151-H190 AromaticContact CE2-CG 3.77Å; Y151-H190 AromaticContact CE2-ND1 3.86Å; Y151-H190 HydrophobicContact CG-CB 3.55Å; Y151-H190 AromaticContact CZ-ND1 3.92Å; H190-S207 PolarHBondContact N-O 3.06Å; H190-S207 PolarHBondContact O-N 3.47Å; H190-Y220 WeakPolarHBondContact CA-OH 3.47Å; H190-Y220 PolarHBondContact N-OH 2.73Å; H190-Y220 PolarHBondContact O-OH 3.09Å
191Y98.5Very high93.9Very high66 Ų6666.6 Ų66.626%0.25934%0.342SS..EExtended strand (participates in β ladder)trans-117.3132.8175.3167.9-102.9000107.6H193 R204 L205 Y206 Y220 V224Y191-H193 AromaticContact CE1-ND1 4Å; Y191-R204 HydrophobicContact CE2-CB 4.22Å; Y191-R204 HydrophobicContact CE2-CG 4.49Å; Y191-R204 PolarHBondContact OH-NH1 2.89Å; Y191-L205 WeakPolarHBondContact CA-O 3.14Å; Y191-L205 WeakPolarHBondContact CD2-O 3.33Å; Y191-Y206 AromaticContact CD2-CD1 3.7Å; Y191-Y206 HydrophobicContact CD2-CD1 3.7Å; Y191-Y206 AromaticContact CD2-CE1 3.45Å; Y191-Y206 HydrophobicContact CD2-CE1 3.45Å; Y191-Y206 VanDerWaalsContact CD2-CE1 3.45Å; Y191-Y206 HydrophobicContact CD2-CG 4.43Å; Y191-Y206 AromaticContact CD2-CZ 3.99Å; Y191-Y206 HydrophobicContact CE2-CD1 4.34Å; Y191-Y206 AromaticContact CE2-CE1 3.68Å; Y191-Y206 HydrophobicContact CE2-CE1 3.68Å; Y191-Y206 AromaticContact CE2-CZ 3.78Å; Y191-Y220 WeakPolarHBondContact CB-OH 3.49Å; Y191-Y220 PolarHBondContact N-OH 3.31Å; Y191-V224 HydrophobicContact CD1-CG1 4.39Å; Y191-V224 HydrophobicContact CD2-CG1 3.86Å; Y191-V224 HydrophobicContact CE2-CG1 4.26Å; Y191-V224 HydrophobicContact CG-CG1 3.91Å
192Q97.9Very high93.9Very high44 Ų4462.6 Ų62.621%0.20633%0.325CS..EExtended strand (participates in β ladder)trans-139.6155172.6176.755-22.700109.8T144 T148 L205T144-Q192 VanDerWaalsContact CB-NE2 3.3Å; T144-Q192 PolarHBondContact OG1-NE2 3.34Å; T148-Q192 WeakPolarHBondContact OG1-CB 3.37Å; Q192-L205 PolarHBondContact N-O 3.11Å; Q192-L205 PolarHBondContact O-N 2.8Å
193H97.5Very high94.1Very high93 Ų9357.8 Ų57.843%0.43130%0.304SS..EExtended strand (participates in β ladder)trans-144.9156.4169.372.8-62.6000111.2Y191 I203 R204Y191-H193 AromaticContact CE1-ND1 4Å; H193-I203 CarbonylContact C-O 3.43Å; H193-I203 WeakPolarHBondContact CA-O 3.44Å; H193-I203 WeakPolarHBondContact CB-O 3.47Å; H193-R204 HydrophobicContact CB-CG 4.18Å
194F97.8Very high94.3Very high14 Ų1458.5 Ų58.56%0.06130%0.304CS..EExtended strand (participates in β ladder)trans-148.7165.6170.458.9-95.5000109.5I135 V137 P138 A141 I203 L205I135-F194 HydrophobicContact CG2-CE2 4.12Å; I135-F194 HydrophobicContact CG2-CZ 4.11Å; V137-F194 HydrophobicContact CB-CZ 4.48Å; V137-F194 HydrophobicContact CG1-CE1 4.41Å; V137-F194 HydrophobicContact CG1-CE2 4.36Å; V137-F194 HydrophobicContact CG1-CZ 4.13Å; V137-F194 HydrophobicContact CG2-CE2 4.46Å; V137-F194 HydrophobicContact CG2-CZ 4.01Å; P138-F194 HydrophobicContact CG-CD2 4.07Å; A141-F194 HydrophobicContact CB-CB 3.75Å; A141-F194 HydrophobicContact CB-CD1 4.01Å; A141-F194 HydrophobicContact CB-CD2 4.44Å; A141-F194 HydrophobicContact CB-CG 3.84Å; F194-I203 HydrophobicContact CD1-CB 4.48Å; F194-I203 HydrophobicContact CD2-CB 4.01Å; F194-I203 HydrophobicContact CD2-CG1 4.1Å; F194-I203 HydrophobicContact CE1-CB 4.17Å; F194-I203 HydrophobicContact CE1-CG2 4Å; F194-I203 HydrophobicContact CE2-CB 3.66Å; F194-I203 HydrophobicContact CE2-CG1 3.61Å; F194-I203 HydrophobicContact CE2-CG2 4.05Å; F194-I203 HydrophobicContact CG-CB 4.41Å; F194-I203 HydrophobicContact CZ-CB 3.75Å; F194-I203 HydrophobicContact CZ-CG1 4.08Å; F194-I203 HydrophobicContact CZ-CG2 3.61Å; F194-I203 PolarHBondContact N-O 3.45Å; F194-I203 PolarHBondContact O-N 3.13Å; F194-L205 HydrophobicContact CD1-CD1 4.05Å; F194-L205 HydrophobicContact CE1-CD1 3.62Å
195L96Very high94.7Very high89 Ų8955.8 Ų55.847%0.46628%0.282SS..EExtended strand (participates in β ladder)trans-94.7136.2170.4-58.9-178.1000108.7P138 K200 F201P138-L195 WeakPolarHBondContact CG-O 3.1Å; L195-K200 HydrophobicContact CB-CD 4.32Å; L195-F201 CarbonylContact C-O 3.59Å; L195-F201 WeakPolarHBondContact CA-O 3.3Å
196S90.5Very high94.9Very high0 Ų046.5 Ų46.50%025%0.245CC..  trans-60.3157.6170.666.10000111.2D13 K200 F201D13-S196 WeakPolarHBondContact OD2-CB 3.5Å; D13-S196 PolarHBondContact OD2-OG 3.33Å; S196-K200 WeakPolarHBondContact O-CA 3.15Å; S196-K200 WeakPolarHBondContact O-CD 3.4Å; S196-K200 PolarHBondContact O-N 3.06Å; S196-K200 PolarHBondContact OG-N 3.08Å; S196-F201 PolarHBondContact N-O 3.31Å; S196-F201 WeakPolarHBondContact OG-CB 3.3Å; S196-F201 WeakPolarHBondContact OG-CD2 3.44Å; S196-F201 PolarHBondContact OG-N 3Å
197T86.6Confident95.1Very high25 Ų2542.1 Ų42.115%0.15322%0.215CC..THydrogen-bonded Turntrans-61.8-54.2-169.7-60.60000113.4D13 D99 K200D13-T197 PolarHBondContact OD1-N 3.39Å; D99-T197 VanDerWaalsContact OD2-CB 3.29Å; D99-T197 WeakPolarHBondContact OD2-CB 3.44Å; D99-T197 WeakPolarHBondContact OD2-CG2 3.17Å; D99-T197 PolarHBondContact OD2-OG1 2.88Å; T197-K200 WeakPolarHBondContact O-CE 3.14Å; T197-K200 PolarHBondContact O-NZ 2.97Å
198F84.7Confident95.1Very high90 Ų9038.3 Ų38.340%0.39519%0.19SC..THydrogen-bonded Turntrans-92.5-61.2-165-56-67.2000112.5M11 D13 I136 K200M11-F198 HydrophobicContact CB-CD1 4.3Å; M11-F198 HydrophobicContact CB-CD2 3.69Å; M11-F198 HydrophobicContact CB-CE1 4.02Å; M11-F198 HydrophobicContact CB-CE2 3.4Å; M11-F198 VanDerWaalsContact CB-CE2 3.4Å; M11-F198 HydrophobicContact CB-CG 4.18Å; M11-F198 HydrophobicContact CB-CZ 3.61Å; M11-F198 HydrophobicContact CE-CE1 4.3Å; M11-F198 HydrophobicContact CE-CE2 3.73Å; M11-F198 HydrophobicContact CE-CZ 3.3Å; M11-F198 HydrophobicContact CG-CE1 4.42Å; M11-F198 HydrophobicContact CG-CE2 4.28Å; M11-F198 HydrophobicContact CG-CZ 4.05Å; M11-F198 HydrophobicContact SD-CE1 3.71Å; M11-F198 HydrophobicContact SD-CE2 4.04Å; M11-F198 HydrophobicContact SD-CZ 3.3Å; M11-F198 WeakPolarHBondContact SD-CZ 3.34Å; D13-F198 WeakPolarHBondContact OD1-CB 3.32Å; D13-F198 WeakPolarHBondContact OD1-CD2 3.24Å; D13-F198 PolarHBondContact OD1-N 3.42Å; I136-F198 HydrophobicContact CG2-CE2 4.44Å; F198-K200 VanDerWaalsContact C-N 3.33Å
199G85.5Confident95.1Very high44 Ų4435.7 Ų35.745%0.45418%0.179SC..THydrogen-bonded Turntrans-83-3.4-179.200000114.7D13 F201D13-G199 WeakPolarHBondContact OD2-CA 3.26Å; D13-G199 PolarHBondContact OD2-N 2.83Å; G199-F201 PolarHBondContact O-N 2.83Å
200K89.1Confident95Very high124 Ų12439.6 Ų39.654%0.53919%0.189SC..  trans54.433.6178.1-56.3-58.4-175.8-159.80113.6L195 S196 T197 F198L195-K200 HydrophobicContact CB-CD 4.32Å; S196-K200 WeakPolarHBondContact O-CA 3.15Å; S196-K200 WeakPolarHBondContact O-CD 3.4Å; S196-K200 PolarHBondContact O-N 3.06Å; S196-K200 PolarHBondContact OG-N 3.08Å; T197-K200 WeakPolarHBondContact O-CE 3.14Å; T197-K200 PolarHBondContact O-NZ 2.97Å; F198-K200 VanDerWaalsContact C-N 3.33Å
201F92.4Very high94.9Very high27 Ų2742.4 Ų42.412%0.11820%0.201CC..PPolyproline II helixtrans-65.1135.9173.7-61.5-77.2000109.9D13 W14 A31 N32 L195 S196 G199 I203 I307D13-F201 HydrophobicContact CB-CD2 4.15Å; D13-F201 HydrophobicContact CB-CE2 4.47Å; D13-F201 WeakPolarHBondContact OD2-CD2 3.47Å; W14-F201 AromaticContact CD1-CD2 3.79Å; W14-F201 AromaticContact NE1-CD2 3.27Å; W14-F201 VanDerWaalsContact NE1-CD2 3.27Å; W14-F201 AromaticContact NE1-CE2 3.6Å; W14-F201 AromaticContact NE1-CG 3.56Å; A31-F201 HydrophobicContact CB-CE2 4.12Å; N32-F201 WeakPolarHBondContact O-CZ 3.47Å; L195-F201 CarbonylContact C-O 3.59Å; L195-F201 WeakPolarHBondContact CA-O 3.3Å; S196-F201 PolarHBondContact N-O 3.31Å; S196-F201 WeakPolarHBondContact OG-CB 3.3Å; S196-F201 WeakPolarHBondContact OG-CD2 3.44Å; S196-F201 PolarHBondContact OG-N 3Å; G199-F201 PolarHBondContact O-N 2.83Å; F201-I203 HydrophobicContact CB-CD1 4.47Å; F201-I203 PolarHBondContact O-N 2.67Å; F201-I307 HydrophobicContact CB-CG2 4.41Å
202S96.3Very high94.8Very high17 Ų1740.1 Ų40.112%0.11920%0.198CC..EExtended strand (participates in β ladder)trans-74.9116.5175.1-167.50000110.1E308S202-E308 PolarHBondContact O-N 2.85Å
203I97.8Very high94.7Very high0 Ų043.8 Ų43.80%022%0.215CC..EExtended strand (participates in β ladder)trans-101121.2174-49.6-59.1000108I135 H193 F194 F201 L205 V305 C306 I307I135-I203 HydrophobicContact CD1-CG2 4.05Å; I135-I203 HydrophobicContact CG2-CG1 4.31Å; H193-I203 CarbonylContact C-O 3.43Å; H193-I203 WeakPolarHBondContact CA-O 3.44Å; H193-I203 WeakPolarHBondContact CB-O 3.47Å; F194-I203 HydrophobicContact CD1-CB 4.48Å; F194-I203 HydrophobicContact CD2-CB 4.01Å; F194-I203 HydrophobicContact CD2-CG1 4.1Å; F194-I203 HydrophobicContact CE1-CB 4.17Å; F194-I203 HydrophobicContact CE1-CG2 4Å; F194-I203 HydrophobicContact CE2-CB 3.66Å; F194-I203 HydrophobicContact CE2-CG1 3.61Å; F194-I203 HydrophobicContact CE2-CG2 4.05Å; F194-I203 HydrophobicContact CG-CB 4.41Å; F194-I203 HydrophobicContact CZ-CB 3.75Å; F194-I203 HydrophobicContact CZ-CG1 4.08Å; F194-I203 HydrophobicContact CZ-CG2 3.61Å; F194-I203 PolarHBondContact N-O 3.45Å; F194-I203 PolarHBondContact O-N 3.13Å; F201-I203 HydrophobicContact CB-CD1 4.47Å; F201-I203 PolarHBondContact O-N 2.67Å; I203-L205 HydrophobicContact CG2-CD1 3.87Å; I203-V305 HydrophobicContact CG2-CG1 4.19Å; I203-C306 CarbonylContact C-O 3.57Å; I203-C306 WeakPolarHBondContact CA-O 3.45Å; I203-I307 HydrophobicContact CD1-CB 4.44Å; I203-I307 HydrophobicContact CD1-CG1 3.88Å; I203-I307 HydrophobicContact CD1-CG2 4.35Å
204R98.5Very high94.6Very high48 Ų4841.2 Ų41.218%0.18120%0.204CC..EExtended strand (participates in β ladder)trans-118.2130.4-175.8-62.8175-177.8-101.55.4110.5Y191 H193 Y206 V305 C306 E308Y191-R204 HydrophobicContact CE2-CB 4.22Å; Y191-R204 HydrophobicContact CE2-CG 4.49Å; Y191-R204 PolarHBondContact OH-NH1 2.89Å; H193-R204 HydrophobicContact CB-CG 4.18Å; R204-Y206 HydrophobicContact CB-CE2 3.91Å; R204-V305 CarbonylContact O-C 3.03Å; R204-V305 WeakPolarHBondContact O-CA 3.15Å; R204-C306 HydrophobicContact CB-CB 4.26Å; R204-C306 PolarHBondContact N-O 2.87Å; R204-C306 PolarHBondContact O-N 2.93Å; R204-E308 IonicContact CZ-OE2 3.6Å; R204-E308 IonicContact NE-OE2 3.55Å; R204-E308 PolarHBondContact NE-OE2 3.06Å; R204-E308 IonicContact NH2-OE2 2.75Å; R204-E308 PolarHBondContact NH2-OE2 2.61Å
205L98.7Very high94.5Very high0 Ų041.2 Ų41.20%020%0.204CC..EExtended strand (participates in β ladder)trans-120.2129.6-175.5-66.677.3000109.1W102 L145 T148 Y191 Q192 F194 I203 V304 V305W102-L205 HydrophobicContact CH2-CD2 3.49Å; W102-L205 VanDerWaalsContact CH2-CD2 3.49Å; W102-L205 HydrophobicContact CH2-CG 4.21Å; W102-L205 HydrophobicContact CZ3-CD2 3.64Å; W102-L205 HydrophobicContact CZ3-CG 4.21Å; L145-L205 HydrophobicContact CD1-CD2 3.47Å; L145-L205 VanDerWaalsContact CD1-CD2 3.47Å; T148-L205 HydrophobicContact CG2-CB 3.77Å; T148-L205 HydrophobicContact CG2-CD2 3.65Å; T148-L205 HydrophobicContact CG2-CG 4.39Å; Y191-L205 WeakPolarHBondContact CA-O 3.14Å; Y191-L205 WeakPolarHBondContact CD2-O 3.33Å; Q192-L205 PolarHBondContact N-O 3.11Å; Q192-L205 PolarHBondContact O-N 2.8Å; F194-L205 HydrophobicContact CD1-CD1 4.05Å; F194-L205 HydrophobicContact CE1-CD1 3.62Å; I203-L205 HydrophobicContact CG2-CD1 3.87Å; L205-V304 WeakPolarHBondContact CA-O 3.34Å; L205-V305 HydrophobicContact CG-CG1 4.44Å; L205-V305 HydrophobicContact CG-CG2 4.38Å
206Y98.7Very high94.6Very high0 Ų037 Ų370%018%0.182CC..EExtended strand (participates in β ladder)trans-122.7120.3174.1-51.3-94.9000107.2Y191 R204 I216 Y220 V221 V224 G303 V304Y191-Y206 AromaticContact CD2-CD1 3.7Å; Y191-Y206 HydrophobicContact CD2-CD1 3.7Å; Y191-Y206 AromaticContact CD2-CE1 3.45Å; Y191-Y206 HydrophobicContact CD2-CE1 3.45Å; Y191-Y206 VanDerWaalsContact CD2-CE1 3.45Å; Y191-Y206 HydrophobicContact CD2-CG 4.43Å; Y191-Y206 AromaticContact CD2-CZ 3.99Å; Y191-Y206 HydrophobicContact CE2-CD1 4.34Å; Y191-Y206 AromaticContact CE2-CE1 3.68Å; Y191-Y206 HydrophobicContact CE2-CE1 3.68Å; Y191-Y206 AromaticContact CE2-CZ 3.78Å; R204-Y206 HydrophobicContact CB-CE2 3.91Å; Y206-I216 WeakPolarHBondContact O-CD1 3.28Å; Y206-Y220 HydrophobicContact CD1-CE1 4.27Å; Y206-V221 HydrophobicContact CD1-CG2 4.18Å; Y206-V221 HydrophobicContact CD2-CG1 4.29Å; Y206-V221 HydrophobicContact CD2-CG2 4.09Å; Y206-V221 HydrophobicContact CE2-CG1 4.24Å; Y206-V221 HydrophobicContact CG-CB 4.5Å; Y206-V221 HydrophobicContact CG-CG1 4.47Å; Y206-V221 HydrophobicContact CG-CG2 3.75Å; Y206-V224 HydrophobicContact CD1-CB 4.22Å; Y206-V224 HydrophobicContact CD1-CG1 4.28Å; Y206-V224 HydrophobicContact CE1-CB 3.79Å; Y206-V224 HydrophobicContact CE1-CG1 3.67Å; Y206-G303 CarbonylContact O-C 3.37Å; Y206-G303 VanDerWaalsContact O-CA 3.31Å; Y206-G303 WeakPolarHBondContact O-CA 3.18Å; Y206-V304 HydrophobicContact CD2-CB 4.36Å; Y206-V304 HydrophobicContact CD2-CG1 4.45Å; Y206-V304 PolarHBondContact N-O 3.11Å; Y206-V304 PolarHBondContact O-N 2.74Å
207S98.6Very high94.9Very high0 Ų037 Ų370%018%0.182CC..EExtended strand (participates in β ladder)trans-124.7145.7-178.8-65.80000110.7T148 Q152 T189 H190 S302T148-S207 WeakPolarHBondContact CG2-OG 3.49Å; T148-S207 WeakPolarHBondContact O-CB 3.06Å; T148-S207 PolarHBondContact O-OG 3.29Å; Q152-S207 VanDerWaalsContact CG-OG 3.23Å; Q152-S207 WeakPolarHBondContact CG-OG 3.19Å; Q152-S207 PolarHBondContact NE2-OG 3.32Å; T189-S207 CarbonylContact C-O 3.45Å; T189-S207 VanDerWaalsContact CA-O 3.24Å; T189-S207 WeakPolarHBondContact CA-O 3.42Å; H190-S207 PolarHBondContact N-O 3.06Å; H190-S207 PolarHBondContact O-N 3.47Å; S207-S302 WeakPolarHBondContact CA-O 3.41Å
208K98.1Very high95.3Very high1 Ų137 Ų370%0.00418%0.184CC..EExtended strand (participates in β ladder)trans-132.1140.4167.972.4169.2172.447.20111Y151 F188 T189 L214 I216 H297 V300 S301 S302Y151-K208 CarbonylContact O-C 3.54Å; F188-K208 WeakPolarHBondContact O-CA 3.42Å; T189-K208 HydrophobicContact CG2-CB 3.97Å; K208-L214 HydrophobicContact CD-CD1 3.73Å; K208-L214 HydrophobicContact CD-CG 4.2Å; K208-L214 WeakPolarHBondContact CD-O 3.36Å; K208-L214 WeakPolarHBondContact CE-O 3.25Å; K208-I216 HydrophobicContact CD-CB 4.01Å; K208-I216 HydrophobicContact CG-CB 4.37Å; K208-I216 HydrophobicContact CG-CD1 4.16Å; K208-H297 PolarHBondContact NZ-O 2.82Å; K208-V300 PolarHBondContact NZ-O 2.94Å; K208-S301 CarbonylContact O-C 3.41Å; K208-S301 VanDerWaalsContact O-CA 3.26Å; K208-S301 WeakPolarHBondContact O-CA 3.39Å; K208-S301 VanDerWaalsContact O-CB 3.31Å; K208-S301 WeakPolarHBondContact O-CB 3.35Å; K208-S302 WeakPolarHBondContact CE-OG 3.05Å; K208-S302 VanDerWaalsContact CG-OG 3.27Å; K208-S302 WeakPolarHBondContact CG-OG 3.04Å; K208-S302 PolarHBondContact N-O 3.19Å; K208-S302 PolarHBondContact NZ-OG 2.61Å; K208-S302 PolarHBondContact O-N 3.03Å
209S97.8Very high95.8Very high0 Ų040.6 Ų40.60%020%0.195CC..  trans-82.6167.4169.679.90000111.3Y151 E153 F188 K211 G212Y151-S209 WeakPolarHBondContact O-CA 2.99Å; Y151-S209 PolarHBondContact O-N 3.45Å; Y151-S209 VanDerWaalsContact O-N 3.11Å; E153-S209 VanDerWaalsContact OE1-CB 3.3Å; E153-S209 WeakPolarHBondContact OE1-CB 2.92Å; F188-S209 WeakPolarHBondContact CB-OG 3.31Å; F188-S209 PolarHBondContact O-N 2.85Å; F188-S209 PolarHBondContact O-OG 2.82Å; S209-K211 PolarHBondContact O-N 2.82Å; S209-G212 PolarHBondContact O-N 3.09Å
210R96Very high96.4Very high113 Ų11339.8 Ų39.843%0.42618%0.178SC..G310 helixtrans-59.1-38.6179.8-169.8177.6-168.8-176.73.1112E153 G212 H213 A299E153-R210 WeakPolarHBondContact OE1-CB 3.32Å; E153-R210 PolarHBondContact OE1-N 3.1Å; R210-G212 PolarHBondContact O-N 3.24Å; R210-H213 PolarHBondContact O-N 3.08Å; R210-A299 WeakPolarHBondContact CG-O 3.45Å; R210-A299 PolarHBondContact NE-O 2.83Å
211K96.3Very high96.8Very high95 Ų9533.9 Ų33.941%0.41315%0.153SC..G310 helixtrans-65-16.8178.5-73.3-175.1173.8174.10113.5L183 A184 F188 S209 H213L183-K211 WeakPolarHBondContact O-CD 3.42Å; L183-K211 WeakPolarHBondContact O-CE 3.19Å; L183-K211 PolarHBondContact O-NZ 2.91Å; A184-K211 PolarHBondContact O-NZ 2.95Å; F188-K211 HydrophobicContact CD1-CB 3.64Å; F188-K211 HydrophobicContact CD1-CD 4.23Å; F188-K211 HydrophobicContact CD2-CB 3.97Å; F188-K211 HydrophobicContact CE1-CB 3.69Å; F188-K211 HydrophobicContact CE1-CD 3.53Å; F188-K211 HydrophobicContact CE1-CG 4.28Å; F188-K211 HydrophobicContact CE2-CB 4.02Å; F188-K211 HydrophobicContact CG-CB 3.79Å; F188-K211 HydrophobicContact CZ-CB 3.89Å; F188-K211 HydrophobicContact CZ-CD 3.81Å; F188-K211 HydrophobicContact CZ-CG 4.5Å; S209-K211 PolarHBondContact O-N 2.82Å; K211-H213 PolarHBondContact O-CD2 2.98Å; K211-H213 VanDerWaalsContact O-CD2 3.27Å; K211-H213 PolarHBondContact O-N 3.3Å
212G95.7Very high97Very high18 Ų1832.7 Ų32.719%0.18615%0.147CC..G310 helixtrans-65.7-25.2177.900000113.9S209 R210 L214S209-G212 PolarHBondContact O-N 3.09Å; R210-G212 PolarHBondContact O-N 3.24Å; G212-L214 PolarHBondContact O-N 3.25Å
213H95.7Very high97Very high121 Ų12137.1 Ų37.156%0.5617%0.168SC*.  trans45.736.2174.4-70.2-63.6000115.8R210 K211 T298R210-H213 PolarHBondContact O-N 3.08Å; K211-H213 PolarHBondContact O-CD2 2.98Å; K211-H213 VanDerWaalsContact O-CD2 3.27Å; K211-H213 PolarHBondContact O-N 3.3Å; H213-T298 CarbonylContact C-O 3.6Å; H213-T298 WeakPolarHBondContact CA-O 3.44Å
214L95.9Very high96.9Very high39 Ų3939.9 Ų39.920%0.20418%0.184CC..SBendtrans-130.4161.4-174.262.782.5000111.9T189 K208 G212 R219 T298T189-L214 HydrophobicContact CG2-CD2 3.84Å; K208-L214 HydrophobicContact CD-CD1 3.73Å; K208-L214 HydrophobicContact CD-CG 4.2Å; K208-L214 WeakPolarHBondContact CD-O 3.36Å; K208-L214 WeakPolarHBondContact CE-O 3.25Å; G212-L214 PolarHBondContact O-N 3.25Å; L214-R219 HydrophobicContact CB-CB 4.18Å; L214-R219 HydrophobicContact CD1-CB 4.29Å; L214-T298 PolarHBondContact N-O 3.16Å; L214-T298 WeakPolarHBondContact O-CA 3.44Å
215D95.5Very high96.8Very high14 Ų1438 Ų388%0.07518%0.179CC..  trans-77.9118.8166.4170.351.6000110.6Y217 S218 R219 L241 R293 T298D215-Y217 PolarHBondContact O-N 3.21Å; D215-S218 WeakPolarHBondContact OD2-CB 3.1Å; D215-S218 PolarHBondContact OD2-N 2.8Å; D215-S218 PolarHBondContact OD2-OG 2.81Å; D215-R219 WeakPolarHBondContact O-CB 3.08Å; D215-R219 PolarHBondContact O-N 3.45Å; D215-R219 VanDerWaalsContact O-N 3.1Å; D215-L241 HydrophobicContact CB-CD1 3.96Å; D215-R293 IonicContact OD1-NH1 3Å; D215-R293 PolarHBondContact OD1-NH1 2.87Å; D215-R293 IonicContact OD2-CZ 3.33Å; D215-R293 IonicContact OD2-NH1 2.77Å; D215-R293 PolarHBondContact OD2-NH1 3.24Å; D215-T298 HydrophobicContact CB-CG2 4.35Å
216I97.5Very high96.7Very high0 Ų046.5 Ų46.50%021%0.211CC..Hα-helixtrans-61.1-34.3-174.8-170.4161000112Y206 K208 Y220 V221 A291 S302 V304Y206-I216 WeakPolarHBondContact O-CD1 3.28Å; K208-I216 HydrophobicContact CD-CB 4.01Å; K208-I216 HydrophobicContact CG-CB 4.37Å; K208-I216 HydrophobicContact CG-CD1 4.16Å; I216-Y220 HydrophobicContact CG1-CD1 4.43Å; I216-Y220 WeakPolarHBondContact O-CB 3.2Å; I216-Y220 PolarHBondContact O-N 2.89Å; I216-V221 HydrophobicContact CG1-CG2 4.12Å; I216-V221 WeakPolarHBondContact O-CG2 3.33Å; I216-V221 PolarHBondContact O-N 3.07Å; I216-A291 HydrophobicContact CG2-CB 3.67Å; I216-S302 WeakPolarHBondContact CD1-OG 3.2Å; I216-V304 HydrophobicContact CD1-CG2 3.87Å; I216-V304 HydrophobicContact CG1-CG2 4.04Å; I216-V304 HydrophobicContact CG2-CG2 4.09Å
217Y97.3Very high96.6Very high0 Ų046.6 Ų46.60%021%0.212CC..Iπ-helixtrans-72-64.3-177.3-58.1-80000111.3D215 V221 T222 L229 V231 A276 S289 A291 R293 V304D215-Y217 PolarHBondContact O-N 3.21Å; Y217-V221 PolarHBondContact O-N 2.82Å; Y217-T222 PolarHBondContact O-N 3.2Å; Y217-T222 PolarHBondContact O-OG1 2.78Å; Y217-L229 HydrophobicContact CD1-CD1 4.22Å; Y217-V231 HydrophobicContact CD1-CG1 4.17Å; Y217-V231 HydrophobicContact CD1-CG2 3.78Å; Y217-V231 HydrophobicContact CD2-CG1 4.41Å; Y217-V231 HydrophobicContact CE1-CG1 3.78Å; Y217-V231 HydrophobicContact CE1-CG2 4.16Å; Y217-V231 HydrophobicContact CE2-CG1 4.03Å; Y217-V231 HydrophobicContact CG-CG1 4.45Å; Y217-V231 HydrophobicContact CG-CG2 4.04Å; Y217-A276 HydrophobicContact CD1-CB 4.35Å; Y217-A276 HydrophobicContact CE1-CB 4.07Å; Y217-S289 WeakPolarHBondContact OH-CB 3.44Å; Y217-S289 PolarHBondContact OH-OG 2.79Å; Y217-A291 HydrophobicContact CE2-CB 3.79Å; Y217-A291 WeakPolarHBondContact CE2-O 3.37Å; Y217-A291 PolarHBondContact OH-O 3.41Å; Y217-R293 VanDerWaalsContact CD2-CD 3.49Å; Y217-R293 HydrophobicContact CD2-CG 4.38Å; Y217-R293 HydrophobicContact CE2-CG 4.37Å; Y217-V304 HydrophobicContact CD1-CG2 4.48Å; Y217-V304 HydrophobicContact CE1-CG2 4.09Å
218S95.7Very high96.5Very high27 Ų2746.8 Ų46.819%0.18921%0.214CC..Iπ-helixtrans-83.1-17-168.187.60000114.6D215 T222 T251D215-S218 WeakPolarHBondContact OD2-CB 3.1Å; D215-S218 PolarHBondContact OD2-N 2.8Å; D215-S218 PolarHBondContact OD2-OG 2.81Å; S218-T222 PolarHBondContact O-OG1 2.67Å; S218-T251 WeakPolarHBondContact CA-OG1 3.45Å; S218-T251 VanDerWaalsContact CB-OG1 3.27Å; S218-T251 WeakPolarHBondContact CB-OG1 3.25Å
219R95.5Very high96.4Very high164 Ų16446.7 Ų46.762%0.61921%0.214SC*.Iπ-helixtrans-109.9-8.3-179.2-61-64.3-172.3172.4-0113.3L214 D215L214-R219 HydrophobicContact CB-CB 4.18Å; L214-R219 HydrophobicContact CD1-CB 4.29Å; D215-R219 WeakPolarHBondContact O-CB 3.08Å; D215-R219 PolarHBondContact O-N 3.45Å; D215-R219 VanDerWaalsContact O-N 3.1Å
220Y97.2Very high96.4Very high28 Ų2847.3 Ų47.311%0.1122%0.217CC..Iπ-helixtrans-134.2-63.2-178.6-169.4-126.2000113.5T189 H190 Y191 Y206 I216 T222 M223 V224T189-Y220 VanDerWaalsContact CB-CZ 3.46Å; T189-Y220 HydrophobicContact CG2-CD1 4.14Å; T189-Y220 HydrophobicContact CG2-CD2 3.99Å; T189-Y220 HydrophobicContact CG2-CE1 4.29Å; T189-Y220 HydrophobicContact CG2-CE2 4.16Å; T189-Y220 HydrophobicContact CG2-CG 4Å; T189-Y220 WeakPolarHBondContact OG1-CE2 3.27Å; H190-Y220 WeakPolarHBondContact CA-OH 3.47Å; H190-Y220 PolarHBondContact N-OH 2.73Å; H190-Y220 PolarHBondContact O-OH 3.09Å; Y191-Y220 WeakPolarHBondContact CB-OH 3.49Å; Y191-Y220 PolarHBondContact N-OH 3.31Å; Y206-Y220 HydrophobicContact CD1-CE1 4.27Å; I216-Y220 HydrophobicContact CG1-CD1 4.43Å; I216-Y220 WeakPolarHBondContact O-CB 3.2Å; I216-Y220 PolarHBondContact O-N 2.89Å; Y220-T222 PolarHBondContact O-N 2.95Å; Y220-M223 PolarHBondContact O-N 3.24Å; Y220-M223 VanDerWaalsContact O-N 3.14Å; Y220-V224 HydrophobicContact CD2-CG2 3.87Å; Y220-V224 HydrophobicContact CE2-CG2 3.52Å; Y220-V224 WeakPolarHBondContact O-CG2 3.5Å; Y220-V224 PolarHBondContact O-N 3.2Å
221V97.9Very high96.5Very high0 Ų042 Ų420%020%0.197CC..Iπ-helixtrans-58.8-49.7-176.41790000111.1Y206 I216 Y217 M223 V224 A225 L229 V304Y206-V221 HydrophobicContact CD1-CG2 4.18Å; Y206-V221 HydrophobicContact CD2-CG1 4.29Å; Y206-V221 HydrophobicContact CD2-CG2 4.09Å; Y206-V221 HydrophobicContact CE2-CG1 4.24Å; Y206-V221 HydrophobicContact CG-CB 4.5Å; Y206-V221 HydrophobicContact CG-CG1 4.47Å; Y206-V221 HydrophobicContact CG-CG2 3.75Å; I216-V221 HydrophobicContact CG1-CG2 4.12Å; I216-V221 WeakPolarHBondContact O-CG2 3.33Å; I216-V221 PolarHBondContact O-N 3.07Å; Y217-V221 PolarHBondContact O-N 2.82Å; V221-M223 VanDerWaalsContact C-N 3.25Å; V221-M223 PolarHBondContact O-N 3.15Å; V221-V224 PolarHBondContact O-N 3.36Å; V221-A225 HydrophobicContact CG1-CB 4.5Å; V221-A225 WeakPolarHBondContact O-CB 3.42Å; V221-A225 PolarHBondContact O-N 3.07Å; V221-L229 HydrophobicContact CB-CD1 3.96Å; V221-L229 HydrophobicContact CG1-CD1 3.75Å; V221-L229 HydrophobicContact CG1-CD2 4.37Å; V221-V304 HydrophobicContact CG2-CB 4.16Å; V221-V304 HydrophobicContact CG2-CG1 4.41Å; V221-V304 HydrophobicContact CG2-CG2 4.02Å
222T96.7Very high96.5Very high1 Ų137.5 Ų37.51%0.00618%0.177CC..Hα-helixtrans-58.3-37.3178.750.90000113.1Y217 S218 Y220 R226 A227 L229 W249 T251Y217-T222 PolarHBondContact O-N 3.2Å; Y217-T222 PolarHBondContact O-OG1 2.78Å; S218-T222 PolarHBondContact O-OG1 2.67Å; Y220-T222 PolarHBondContact O-N 2.95Å; T222-R226 VanDerWaalsContact O-CA 3.27Å; T222-R226 WeakPolarHBondContact O-CA 3.45Å; T222-R226 PolarHBondContact O-N 3.2Å; T222-A227 WeakPolarHBondContact CA-O 3.23Å; T222-A227 WeakPolarHBondContact CG2-O 3.29Å; T222-A227 PolarHBondContact O-N 2.94Å; T222-L229 HydrophobicContact CG2-CB 4.47Å; T222-L229 HydrophobicContact CG2-CD1 3.78Å; T222-L229 HydrophobicContact CG2-CG 3.91Å; T222-W249 HydrophobicContact CG2-CB 4.39Å; T222-T251 WeakPolarHBondContact CG2-OG1 3.24Å
223M95.3Very high96.5Very high111 Ų11136.7 Ų36.755%0.54717%0.169SC..Hα-helixtrans-73.7-40.5-178-61.2-58.7-65.600112.4Y220 V221 W249Y220-M223 PolarHBondContact O-N 3.24Å; Y220-M223 VanDerWaalsContact O-N 3.14Å; V221-M223 VanDerWaalsContact C-N 3.25Å; V221-M223 PolarHBondContact O-N 3.15Å; M223-W249 HydrophobicContact CE-CZ3 4.46Å; M223-W249 HydrophobicContact SD-CE3 4.22Å; M223-W249 HydrophobicContact SD-CZ3 4.36Å
224V96.8Very high96.3Very high57 Ų5733 Ų3335%0.34516%0.157SC..Hα-helixtrans-77.8-43.1179.3179.30000110.8Y191 Y206 Y220 V221 R226Y191-V224 HydrophobicContact CD1-CG1 4.39Å; Y191-V224 HydrophobicContact CD2-CG1 3.86Å; Y191-V224 HydrophobicContact CE2-CG1 4.26Å; Y191-V224 HydrophobicContact CG-CG1 3.91Å; Y206-V224 HydrophobicContact CD1-CB 4.22Å; Y206-V224 HydrophobicContact CD1-CG1 4.28Å; Y206-V224 HydrophobicContact CE1-CB 3.79Å; Y206-V224 HydrophobicContact CE1-CG1 3.67Å; Y220-V224 HydrophobicContact CD2-CG2 3.87Å; Y220-V224 HydrophobicContact CE2-CG2 3.52Å; Y220-V224 WeakPolarHBondContact O-CG2 3.5Å; Y220-V224 PolarHBondContact O-N 3.2Å; V221-V224 PolarHBondContact O-N 3.36Å; V224-R226 VanDerWaalsContact C-N 3.3Å; V224-R226 PolarHBondContact O-N 2.81Å
225A96.7Very high95.8Very high10 Ų1032.5 Ų32.58%0.08315%0.154CC..Hα-helixtrans-74.4-19.8179.100000113.1V221 A227 L283 L285V221-A225 HydrophobicContact CG1-CB 4.5Å; V221-A225 WeakPolarHBondContact O-CB 3.42Å; V221-A225 PolarHBondContact O-N 3.07Å; A225-A227 HydrophobicContact CB-CB 4.41Å; A225-A227 PolarHBondContact O-N 2.61Å; A225-L283 HydrophobicContact CB-CD2 3.96Å; A225-L283 WeakPolarHBondContact O-CD2 3.26Å; A225-L285 HydrophobicContact CB-CD1 4.5Å
226R95.6Very high94.9Very high177 Ų17733.7 Ų33.767%0.66817%0.169SC*.THydrogen-bonded Turntrans5145.2-173.2-60-174.2177.7-170.9-0.9111.9T222 V224 W249T222-R226 VanDerWaalsContact O-CA 3.27Å; T222-R226 WeakPolarHBondContact O-CA 3.45Å; T222-R226 PolarHBondContact O-N 3.2Å; V224-R226 VanDerWaalsContact C-N 3.3Å; V224-R226 PolarHBondContact O-N 2.81Å; R226-W249 VanDerWaalsContact C-CE2 3.45Å; R226-W249 VanDerWaalsContact CA-CE2 3.43Å; R226-W249 HydrophobicContact CB-CD2 4.36Å; R226-W249 HydrophobicContact CB-CH2 3.97Å; R226-W249 HydrophobicContact CB-CZ2 3.51Å; R226-W249 HydrophobicContact CG-CH2 3.72Å; R226-W249 HydrophobicContact CG-CZ2 3.78Å; R226-W249 HydrophobicContact CG-CZ3 4.26Å; R226-W249 PolarHBondContact O-NE1 3.47Å
227A96.7Very high93.7Very high3 Ų342.7 Ų42.73%0.02521%0.208CC..SBendtrans-147.4144.6-177.900000110.1T222 A225 T278T222-A227 WeakPolarHBondContact CA-O 3.23Å; T222-A227 WeakPolarHBondContact CG2-O 3.29Å; T222-A227 PolarHBondContact O-N 2.94Å; A225-A227 HydrophobicContact CB-CB 4.41Å; A225-A227 PolarHBondContact O-N 2.61Å; A227-T278 HydrophobicContact CB-CG2 3.8Å
228G96.2Very high91.9Very high3 Ų352.6 Ų52.63%0.03125%0.247CC..  trans-71165.6171.800000111.3K250 T278 T279G228-K250 CarbonylContact C-O 3.57Å; G228-K250 WeakPolarHBondContact CA-O 3.33Å; G228-T278 CarbonylContact O-C 3.5Å; G228-T278 WeakPolarHBondContact O-CA 3.16Å; G228-T279 WeakPolarHBondContact CA-OG1 3.23Å; G228-T279 PolarHBondContact O-N 2.68Å; G228-T279 PolarHBondContact O-OG1 3.05Å
229L97.3Very high91Very high0 Ų056.5 Ų56.50%026%0.264CS..EExtended strand (participates in β ladder)trans-135.3139.5-176.5-65.9173.4000111.7Y217 V221 T222 V231 K250 T251 Q252 A276 I277 T278Y217-L229 HydrophobicContact CD1-CD1 4.22Å; V221-L229 HydrophobicContact CB-CD1 3.96Å; V221-L229 HydrophobicContact CG1-CD1 3.75Å; V221-L229 HydrophobicContact CG1-CD2 4.37Å; T222-L229 HydrophobicContact CG2-CB 4.47Å; T222-L229 HydrophobicContact CG2-CD1 3.78Å; T222-L229 HydrophobicContact CG2-CG 3.91Å; L229-V231 HydrophobicContact CB-CG2 4.16Å; L229-K250 PolarHBondContact N-O 3.02Å; L229-T251 HydrophobicContact CB-CG2 4.4Å; L229-T251 CarbonylContact O-C 3.51Å; L229-T251 WeakPolarHBondContact O-CA 3.5Å; L229-Q252 PolarHBondContact O-N 3.44Å; L229-A276 HydrophobicContact CD2-CB 4.45Å; L229-I277 CarbonylContact C-O 3.57Å; L229-I277 WeakPolarHBondContact CA-O 3.37Å; L229-T278 HydrophobicContact CD2-CG2 3.74Å
230N96.9Very high90.6Very high12 Ų1253 Ų536%0.06425%0.253CS..EExtended strand (participates in β ladder)trans-102.6128.4158.5-68.2-26.6000108.6Q252 L254 A276 I277N230-Q252 WeakPolarHBondContact CA-O 3.37Å; N230-L254 HydrophobicContact CB-CD2 4.4Å; N230-L254 HydrophobicContact CB-CG 4.33Å; N230-A276 WeakPolarHBondContact O-CA 3.24Å; N230-I277 HydrophobicContact CB-CD1 4.49Å; N230-I277 HydrophobicContact CB-CG1 3.93Å; N230-I277 PolarHBondContact N-O 2.81Å; N230-I277 PolarHBondContact O-N 2.79Å
231V97.4Very high90.3Very high1 Ų153.3 Ų53.31%0.00626%0.256CS..EExtended strand (participates in β ladder)trans-120.3123.8-172-173.80000111.3Y217 L229 T251 Q252 L254 A276 R293Y217-V231 HydrophobicContact CD1-CG1 4.17Å; Y217-V231 HydrophobicContact CD1-CG2 3.78Å; Y217-V231 HydrophobicContact CD2-CG1 4.41Å; Y217-V231 HydrophobicContact CE1-CG1 3.78Å; Y217-V231 HydrophobicContact CE1-CG2 4.16Å; Y217-V231 HydrophobicContact CE2-CG1 4.03Å; Y217-V231 HydrophobicContact CG-CG1 4.45Å; Y217-V231 HydrophobicContact CG-CG2 4.04Å; L229-V231 HydrophobicContact CB-CG2 4.16Å; V231-T251 HydrophobicContact CG2-CG2 3.8Å; V231-Q252 PolarHBondContact N-O 2.95Å; V231-L254 WeakPolarHBondContact O-CB 3.37Å; V231-L254 PolarHBondContact O-N 3.37Å; V231-A276 HydrophobicContact CG2-CB 4.05Å; V231-R293 HydrophobicContact CB-CG 4.12Å; V231-R293 HydrophobicContact CG1-CG 3.68Å
232W97.4Very high90Very high1 Ų157.6 Ų57.60%0.00429%0.285CS..EExtended strand (participates in β ladder)trans-98.8121.1166.4-177.9-100.8000109.5L254 V259 R268 D271 R274 W275W232-L254 HydrophobicContact CB-CD1 3.98Å; W232-L254 HydrophobicContact CE3-CB 3.84Å; W232-L254 HydrophobicContact CE3-CD1 4.42Å; W232-V259 HydrophobicContact CD2-CG1 3.63Å; W232-V259 HydrophobicContact CE3-CG1 3.34Å; W232-V259 HydrophobicContact CG-CG1 4.47Å; W232-V259 HydrophobicContact CH2-CB 4.25Å; W232-V259 HydrophobicContact CH2-CG1 3.63Å; W232-V259 HydrophobicContact CH2-CG2 4.11Å; W232-V259 HydrophobicContact CZ2-CB 4.3Å; W232-V259 HydrophobicContact CZ2-CG1 3.87Å; W232-V259 HydrophobicContact CZ2-CG2 3.7Å; W232-V259 HydrophobicContact CZ3-CB 4.39Å; W232-V259 HydrophobicContact CZ3-CG1 3.33Å; W232-R268 VanDerWaalsContact CD2-NH1 3.29Å; W232-R268 VanDerWaalsContact CE2-NH1 3.3Å; W232-R268 HydrophobicContact CH2-CB 3.87Å; W232-R268 HydrophobicContact CH2-CG 4.49Å; W232-R268 VanDerWaalsContact CH2-CZ 3.45Å; W232-R268 HydrophobicContact CZ2-CB 3.92Å; W232-R268 HydrophobicContact CZ2-CG 4.34Å; W232-D271 PolarHBondContact NE1-OD2 3.34Å; W232-R274 VanDerWaalsContact O-CA 3.32Å; W232-R274 WeakPolarHBondContact O-CA 3.34Å; W232-W275 HydrophobicContact CB-CD2 3.7Å; W232-W275 HydrophobicContact CB-CE3 4.16Å; W232-W275 HydrophobicContact CB-CG 4.22Å; W232-W275 HydrophobicContact CB-CH2 3.98Å; W232-W275 HydrophobicContact CB-CZ2 3.5Å; W232-W275 HydrophobicContact CB-CZ3 4.28Å; W232-W275 AromaticContact CD1-CD1 3.78Å; W232-W275 AromaticContact CD1-CE2 3.8Å; W232-W275 AromaticContact CD1-NE1 3.22Å; W232-W275 HydrophobicContact CD2-CZ2 4.38Å; W232-W275 HydrophobicContact CG-CD2 4.43Å; W232-W275 AromaticContact CG-CE2 3.66Å; W232-W275 AromaticContact CG-CZ2 3.79Å; W232-W275 HydrophobicContact CG-CZ2 3.79Å; W232-W275 AromaticContact CG-NE1 3.58Å; W232-W275 PolarHBondContact N-O 2.98Å; W232-W275 PolarHBondContact O-N 3.38Å
233S95.6Very high89.8Confident2 Ų258.2 Ų58.21%0.01429%0.289CS..  trans-161.8173175.8670000110.6L235 R268 D292 R293S233-L235 PolarHBondContact O-N 3.02Å; S233-R268 PolarHBondContact O-NH1 2.94Å; S233-D292 WeakPolarHBondContact CB-OD1 3.48Å; S233-R293 WeakPolarHBondContact OG-CG 3.15Å; S233-R293 PolarHBondContact OG-N 3.02Å
234S91.9Very high89.5Confident43 Ų4353.8 Ų53.830%0.30127%0.271SS..  trans-65.1128.5173.4-173.50000110.6G236 D292S234-G236 VanDerWaalsContact C-N 3.29Å; S234-G236 PolarHBondContact OG-N 3.25Å; S234-D292 WeakPolarHBondContact CB-OD1 3.14Å; S234-D292 PolarHBondContact N-OD1 3.05Å
235L85.3Confident89.2Confident29 Ų2953.5 Ų53.515%0.15227%0.272CS..  trans-79-16.6173.1-61.3-180000112.2S233 K240 L255S233-L235 PolarHBondContact O-N 3.02Å; L235-K240 HydrophobicContact CB-CB 4.48Å; L235-K240 HydrophobicContact CD2-CB 4.45Å; L235-K240 HydrophobicContact CD2-CD 4.42Å; L235-L255 HydrophobicContact CD1-CD2 3.9Å
236G76.8Confident88.5Confident38 Ų3859.6 Ų59.639%0.39231%0.308SS..  trans60.3-174.5-173.400000113.5S234S234-G236 VanDerWaalsContact C-N 3.29Å; S234-G236 PolarHBondContact OG-N 3.25Å
237K72.2Confident87.8Confident189 Ų18953.2 Ų53.282%0.82230%0.297SS*.SBendtrans-95-26.9-177.9-65.5-176.2178.1-177.10114.6
238Y59.9Low87.5Confident208 Ų20860.7 Ų60.782%0.81633%0.332SS*.SBendtrans-115-41.2-159.5-58.6-66.3000115.3
239M76.1Confident87.4Confident109 Ų10963.5 Ų63.554%0.53734%0.341SS..  trans-154.273.4-170-70.9-174.3-7800112.3R294 R295M239-R294 WeakPolarHBondContact O-CA 3.42Å; M239-R295 HydrophobicContact CB-CB 4.2Å; M239-R295 PolarHBondContact O-N 3.32Å; M239-R295 VanDerWaalsContact O-N 3.11Å
240K85.8Confident87.4Confident90 Ų9067.6 Ų67.639%0.39136%0.359SS..BIsolated β-bridgetrans-64.7140.7165.966.1168.7178.5162.20109.8L235 R293 E326L235-K240 HydrophobicContact CB-CB 4.48Å; L235-K240 HydrophobicContact CD2-CB 4.45Å; L235-K240 HydrophobicContact CD2-CD 4.42Å; K240-R293 CarbonylContact C-O 3.48Å; K240-R293 WeakPolarHBondContact CA-O 3.41Å; K240-E326 IonicContact NZ-OE1 3Å; K240-E326 PolarHBondContact NZ-OE1 3.44Å
241L91.8Very high87.3Confident35 Ų3567 Ų6718%0.18336%0.356CS..PPolyproline II helixtrans-73.9129.1166.6-71.1170.3000107.7D215 N253 R293 R295 T298D215-L241 HydrophobicContact CB-CD1 3.96Å; L241-N253 PolarHBondContact O-ND2 3.27Å; L241-R293 PolarHBondContact N-O 2.87Å; L241-R295 HydrophobicContact CD2-CB 4.34Å; L241-T298 HydrophobicContact CD1-CG2 3.98Å
242P91.7Very high87.2Confident91 Ų9168.5 Ų68.559%0.59136%0.363SS*.PPolyproline II helixtrans-63.6162.717430.3-35.7000110G244 R293P242-G244 PolarHBondContact O-N 2.92Å; P242-R293 PolarHBondContact O-NH2 2.97Å
243S93Very high87.1Confident13 Ų1368.5 Ų68.59%0.09136%0.363CS..PPolyproline II helixtrans-54134.9170.9-65.90000111.1C245 T251 Q252 N253 E326S243-C245 PolarHBondContact O-N 2.94Å; S243-C245 PolarHBondContact O-SG 3.42Å; S243-C245 VanDerWaalsContact O-SG 3.38Å; S243-T251 CarbonylContact C-O 3.43Å; S243-T251 WeakPolarHBondContact CA-O 3.37Å; S243-T251 VanDerWaalsContact CB-O 3.3Å; S243-T251 WeakPolarHBondContact CB-O 3.45Å; S243-Q252 WeakPolarHBondContact OG-CA 3.48Å; S243-N253 PolarHBondContact OG-N 3.3Å; S243-E326 PolarHBondContact N-OE2 3.36Å; S243-E326 WeakPolarHBondContact OG-CB 3.45Å; S243-E326 PolarHBondContact OG-O 2.85Å; S243-E326 VanDerWaalsContact OG-O 3.06Å; S243-E326 PolarHBondContact OG-OE2 3.39Å
244G89.6Confident87.1Confident18 Ų1868.6 Ų68.619%0.18636%0.363CS..BIsolated β-bridgetrans-81.299.818000000110P242 K250 T251P242-G244 PolarHBondContact O-N 2.92Å; G244-K250 VanDerWaalsContact O-CA 3.29Å; G244-K250 WeakPolarHBondContact O-CA 3.49Å; G244-T251 PolarHBondContact N-O 3.23Å; G244-T251 PolarHBondContact O-N 3.48Å
245C89Confident87.1Confident52 Ų5269 Ų6935%0.35136%0.362SS..  trans-109.6-1.2-169.9-57.20000115S243 G247 C328S243-C245 PolarHBondContact O-N 2.94Å; S243-C245 PolarHBondContact O-SG 3.42Å; S243-C245 VanDerWaalsContact O-SG 3.38Å; C245-G247 PolarHBondContact O-N 3.2Å; C245-C328 WeakPolarHBondContact CA-SG 3.19Å; C245-C328 HydrophobicContact CB-CB 3.55Å; C245-C328 WeakPolarHBondContact CB-SG 3.45Å; C245-C328 WeakPolarHBondContact SG-CA 3.21Å; C245-C328 WeakPolarHBondContact SG-CB 3.22Å; C245-C328 CovalentContact SG-SG 2.03Å; C245-C328 PolarHBondContact SG-SG 3.13Å
246T81.7Confident87Confident137 Ų13767.8 Ų67.884%0.8436%0.356SS*.SBendtrans-93.117.1-168.460.60000114.5
247G81.6Confident87.7Confident43 Ų4370.5 Ų70.544%0.44337%0.367SS..SBendtrans-145171.5-176.700000112.6C245 W249C245-G247 PolarHBondContact O-N 3.2Å; G247-W249 VanDerWaalsContact C-N 3.26Å; G247-W249 PolarHBondContact O-N 3.02Å
248E90.8Very high88.8Confident160 Ų16062.5 Ų62.575%0.74834%0.335SS*.SBendtrans-55.8-43.4177.3-174.2-179.6166.300111.4
249W94.9Very high90.5Very high63 Ų6352.6 Ų52.624%0.23930%0.296CS..SBendtrans-103.1105.3178.6-53.5-60.8000111T222 M223 R226 G247T222-W249 HydrophobicContact CG2-CB 4.39Å; M223-W249 HydrophobicContact CE-CZ3 4.46Å; M223-W249 HydrophobicContact SD-CE3 4.22Å; M223-W249 HydrophobicContact SD-CZ3 4.36Å; R226-W249 VanDerWaalsContact C-CE2 3.45Å; R226-W249 VanDerWaalsContact CA-CE2 3.43Å; R226-W249 HydrophobicContact CB-CD2 4.36Å; R226-W249 HydrophobicContact CB-CH2 3.97Å; R226-W249 HydrophobicContact CB-CZ2 3.51Å; R226-W249 HydrophobicContact CG-CH2 3.72Å; R226-W249 HydrophobicContact CG-CZ2 3.78Å; R226-W249 HydrophobicContact CG-CZ3 4.26Å; R226-W249 PolarHBondContact O-NE1 3.47Å; G247-W249 VanDerWaalsContact C-N 3.26Å; G247-W249 PolarHBondContact O-N 3.02Å
250K95.3Very high91.5Very high86 Ų8651.9 Ų51.937%0.37429%0.29SS..  trans-78.9146.6-177.8-62.6173.8172.1-173.70111.5G228 L229 G244 Q252 C328G228-K250 CarbonylContact C-O 3.57Å; G228-K250 WeakPolarHBondContact CA-O 3.33Å; L229-K250 PolarHBondContact N-O 3.02Å; G244-K250 VanDerWaalsContact O-CA 3.29Å; G244-K250 WeakPolarHBondContact O-CA 3.49Å; K250-Q252 HydrophobicContact CB-CG 4.35Å; K250-C328 HydrophobicContact CD-CB 3.71Å
251T96Very high92Very high0 Ų047.6 Ų47.60%027%0.271CS..EExtended strand (participates in β ladder)trans-113.4111.6168.3-580000108.9S218 T222 L229 V231 S243 G244S218-T251 WeakPolarHBondContact CA-OG1 3.45Å; S218-T251 VanDerWaalsContact CB-OG1 3.27Å; S218-T251 WeakPolarHBondContact CB-OG1 3.25Å; T222-T251 WeakPolarHBondContact CG2-OG1 3.24Å; L229-T251 HydrophobicContact CB-CG2 4.4Å; L229-T251 CarbonylContact O-C 3.51Å; L229-T251 WeakPolarHBondContact O-CA 3.5Å; V231-T251 HydrophobicContact CG2-CG2 3.8Å; S243-T251 CarbonylContact C-O 3.43Å; S243-T251 WeakPolarHBondContact CA-O 3.37Å; S243-T251 VanDerWaalsContact CB-O 3.3Å; S243-T251 WeakPolarHBondContact CB-O 3.45Å; G244-T251 PolarHBondContact N-O 3.23Å; G244-T251 PolarHBondContact O-N 3.48Å
252Q95.4Very high92.2Very high31 Ų3148.1 Ų48.115%0.14527%0.274CS..EExtended strand (participates in β ladder)trans-109134-175.1-56.9-174.6-95.800110.6L229 N230 V231 S243 K250 L325L229-Q252 PolarHBondContact O-N 3.44Å; N230-Q252 WeakPolarHBondContact CA-O 3.37Å; V231-Q252 PolarHBondContact N-O 2.95Å; S243-Q252 WeakPolarHBondContact OG-CA 3.48Å; K250-Q252 HydrophobicContact CB-CG 4.35Å; Q252-L325 HydrophobicContact CB-CD1 3.62Å; Q252-L325 HydrophobicContact CB-CD2 4.36Å; Q252-L325 HydrophobicContact CB-CG 4.05Å; Q252-L325 VanDerWaalsContact NE2-CD2 3.33Å
253N95.3Very high92.2Very high1 Ų151.9 Ų51.91%0.00528%0.281CS..EExtended strand (participates in β ladder)trans-82.1128.4177.3-64-36.5000109.6L241 S243 L255 R293 E326L241-N253 PolarHBondContact O-ND2 3.27Å; S243-N253 PolarHBondContact OG-N 3.3Å; N253-L255 HydrophobicContact CB-CD2 4.28Å; N253-L255 PolarHBondContact O-N 3.31Å; N253-R293 VanDerWaalsContact OD1-CG 3.25Å; N253-R293 WeakPolarHBondContact OD1-CG 3.45Å; N253-R293 PolarHBondContact OD1-NE 3.25Å; N253-E326 HydrophobicContact CB-CB 4.1Å; N253-E326 PolarHBondContact ND2-OE2 2.96Å; N253-E326 PolarHBondContact O-N 3.32Å
254L95.3Very high92.3Very high5 Ų554 Ų543%0.02629%0.291CS..EExtended strand (participates in β ladder)trans-70.9119.7159.8-65.9173.4000106.5N230 V231 W232 R268 W275 A320 S323 N324 L325N230-L254 HydrophobicContact CB-CD2 4.4Å; N230-L254 HydrophobicContact CB-CG 4.33Å; V231-L254 WeakPolarHBondContact O-CB 3.37Å; V231-L254 PolarHBondContact O-N 3.37Å; W232-L254 HydrophobicContact CB-CD1 3.98Å; W232-L254 HydrophobicContact CE3-CB 3.84Å; W232-L254 HydrophobicContact CE3-CD1 4.42Å; L254-R268 PolarHBondContact O-NH2 3.08Å; L254-W275 HydrophobicContact CD1-CH2 3.6Å; L254-W275 HydrophobicContact CD1-CZ2 4.36Å; L254-W275 HydrophobicContact CD1-CZ3 3.92Å; L254-A320 HydrophobicContact CD1-CB 3.76Å; L254-A320 HydrophobicContact CD2-CB 3.99Å; L254-S323 WeakPolarHBondContact CB-OG 3.06Å; L254-N324 CarbonylContact C-O 3.58Å; L254-L325 HydrophobicContact CD2-CD1 3.9Å
255L91.2Very high92.7Very high51 Ų5157.4 Ų57.427%0.26731%0.308SS..EExtended strand (participates in β ladder)trans-88.2-26.4-175.1-68.2-179.6000113.1L235 N253 R268 S323 N324 E326L235-L255 HydrophobicContact CD1-CD2 3.9Å; N253-L255 HydrophobicContact CB-CD2 4.28Å; N253-L255 PolarHBondContact O-N 3.31Å; L255-R268 VanDerWaalsContact C-NH2 3.3Å; L255-R268 PolarHBondContact O-NE 3.39Å; L255-R268 PolarHBondContact O-NH2 2.75Å; L255-S323 PolarHBondContact N-OG 3.15Å; L255-N324 HydrophobicContact CB-CB 4.35Å; L255-N324 PolarHBondContact N-O 3.19Å; L255-E326 HydrophobicContact CD1-CB 3.71Å; L255-E326 HydrophobicContact CD1-CG 4.27Å; L255-E326 HydrophobicContact CD2-CB 3.89Å; L255-E326 HydrophobicContact CD2-CG 4.49Å; L255-E326 HydrophobicContact CG-CB 3.72Å
256G84.3Confident93Very high3 Ų355 Ų553%0.03129%0.292CS..EExtended strand (participates in β ladder)trans88.7-150.8-176.200000112.9S258 S323 N324G256-S258 VanDerWaalsContact CA-N 3.34Å; G256-S323 PolarHBondContact N-OG 3.2Å; G256-N324 PolarHBondContact O-N 3.01Å; G256-N324 PolarHBondContact O-ND2 2.96Å
257P91.9Very high93.7Very high95 Ų9550.8 Ų50.862%0.61727%0.268SS*.SBendcis-78.7-11.120.631.7-37.1000115.2R268P257-R268 WeakPolarHBondContact O-CB 3.48Å; P257-R268 PolarHBondContact O-N 3.07Å
258S94.9Very high94.3Very high22 Ų2249.8 Ų49.815%0.15425%0.251CS..EExtended strand (participates in β ladder)trans-141.9165.7-174.955.90000112.5G256 T265 I266G256-S258 VanDerWaalsContact CA-N 3.34Å; S258-T265 WeakPolarHBondContact OG-CG2 3.35Å; S258-I266 WeakPolarHBondContact CA-O 3.18Å; S258-I266 WeakPolarHBondContact CB-O 3.35Å
259V96.1Very high94.4Very high0 Ų048.1 Ų48.10%025%0.247CC..EExtended strand (participates in β ladder)trans-116.5160166.2-79.90000110W232 V261 T265 I266 W275 V319W232-V259 HydrophobicContact CD2-CG1 3.63Å; W232-V259 HydrophobicContact CE3-CG1 3.34Å; W232-V259 HydrophobicContact CG-CG1 4.47Å; W232-V259 HydrophobicContact CH2-CB 4.25Å; W232-V259 HydrophobicContact CH2-CG1 3.63Å; W232-V259 HydrophobicContact CH2-CG2 4.11Å; W232-V259 HydrophobicContact CZ2-CB 4.3Å; W232-V259 HydrophobicContact CZ2-CG1 3.87Å; W232-V259 HydrophobicContact CZ2-CG2 3.7Å; W232-V259 HydrophobicContact CZ3-CB 4.39Å; W232-V259 HydrophobicContact CZ3-CG1 3.33Å; V259-V261 HydrophobicContact CG2-CG2 4.26Å; V259-T265 CarbonylContact O-C 3.54Å; V259-T265 WeakPolarHBondContact O-CA 3.33Å; V259-I266 HydrophobicContact CG2-CB 4.34Å; V259-I266 PolarHBondContact N-O 3.37Å; V259-I266 PolarHBondContact O-N 3.21Å; V259-W275 HydrophobicContact CG1-CZ2 4.08Å; V259-V319 HydrophobicContact CB-CG1 3.79Å; V259-V319 HydrophobicContact CG1-CG1 4.16Å; V259-V319 HydrophobicContact CG2-CG1 4.39Å
260K96.7Very high94.5Very high93 Ų9348 Ų4840%0.40425%0.252SS..EExtended strand (participates in β ladder)trans-112.893.3175.7-169.4176.9179.7177.70110.3N262 I264 V319 T322K260-N262 PolarHBondContact O-N 3.32Å; K260-I264 CarbonylContact C-O 3.57Å; K260-I264 WeakPolarHBondContact CA-O 3.32Å; K260-V319 PolarHBondContact N-O 2.81Å; K260-V319 VanDerWaalsContact N-O 3.16Å; K260-V319 WeakPolarHBondContact O-CA 3.47Å; K260-T322 HydrophobicContact CB-CG2 3.97Å; K260-T322 HydrophobicContact CD-CG2 4.32Å
261V96.4Very high94.5Very high0 Ų044.5 Ų44.50%024%0.237CC..EExtended strand (participates in β ladder)trans-81.7111.8176.9-176.50000108Y18 E27 W37 V259 K263 I264 I266 V319Y18-V261 HydrophobicContact CD1-CG1 4.35Å; Y18-V261 HydrophobicContact CD1-CG2 4.14Å; Y18-V261 HydrophobicContact CD2-CG1 3.83Å; Y18-V261 HydrophobicContact CD2-CG2 3.81Å; Y18-V261 HydrophobicContact CE1-CG2 3.92Å; Y18-V261 HydrophobicContact CE2-CG1 4.44Å; Y18-V261 HydrophobicContact CE2-CG2 3.56Å; Y18-V261 HydrophobicContact CG-CG1 3.77Å; Y18-V261 HydrophobicContact CG-CG2 4.08Å; E27-V261 HydrophobicContact CB-CG1 3.86Å; E27-V261 HydrophobicContact CG-CG1 4Å; W37-V261 HydrophobicContact CH2-CG1 3.61Å; W37-V261 HydrophobicContact CZ2-CG1 4.08Å; W37-V261 HydrophobicContact CZ3-CG1 4.03Å; V259-V261 HydrophobicContact CG2-CG2 4.26Å; V261-K263 PolarHBondContact O-N 3.42Å; V261-I264 PolarHBondContact N-O 2.81Å; V261-I264 PolarHBondContact O-N 3.36Å; V261-I266 HydrophobicContact CB-CD1 4.06Å; V261-I266 HydrophobicContact CG2-CD1 3.7Å; V261-I266 HydrophobicContact CG2-CG1 4.4Å; V261-V319 HydrophobicContact CG2-CG1 3.98Å
262N94.6Very high94.6Very high46 Ų4646.4 Ų46.425%0.24625%0.248CC..THydrogen-bonded Turntrans51.6-108.1-169.3-1705.8000111.6E27 W37 K260E27-N262 HydrophobicContact CG-CB 4.15Å; E27-N262 PolarHBondContact OE1-ND2 3.03Å; E27-N262 WeakPolarHBondContact OE2-CB 3.15Å; E27-N262 PolarHBondContact OE2-ND2 3.31Å; W37-N262 HydrophobicContact CB-CB 4.45Å; W37-N262 HydrophobicContact CD2-CB 3.91Å; W37-N262 HydrophobicContact CG-CB 3.81Å; K260-N262 PolarHBondContact O-N 3.32Å
263K92.3Very high94.6Very high171 Ų17145 Ų4574%0.74324%0.242SC*.THydrogen-bonded Turntrans-98.9-5.5177.8-65.4176.2-173.4171.10113.3V261V261-K263 PolarHBondContact O-N 3.42Å
264I95.6Very high94.7Very high58 Ų5846.3 Ų46.330%0.29725%0.247SC..EExtended strand (participates in β ladder)trans-106.3125.5-165.8-56.5177.2000110.2L20 E27 K260 V261 I266L20-I264 HydrophobicContact CD1-CD1 3.34Å; L20-I264 HydrophobicContact CD2-CB 4.34Å; L20-I264 HydrophobicContact CD2-CD1 3.81Å; L20-I264 HydrophobicContact CD2-CG2 4.15Å; L20-I264 HydrophobicContact CG-CD1 4.21Å; E27-I264 WeakPolarHBondContact OE1-CD1 3.39Å; K260-I264 CarbonylContact C-O 3.57Å; K260-I264 WeakPolarHBondContact CA-O 3.32Å; V261-I264 PolarHBondContact N-O 2.81Å; V261-I264 PolarHBondContact O-N 3.36Å; I264-I266 HydrophobicContact CG2-CG1 4.25Å
265T96.7Very high94.9Very high89 Ų8946 Ų4655%0.54625%0.245SC..EExtended strand (participates in β ladder)trans-84.9124.2173.7-61.90000110S258 V259S258-T265 WeakPolarHBondContact OG-CG2 3.35Å; V259-T265 CarbonylContact O-C 3.54Å; V259-T265 WeakPolarHBondContact O-CA 3.33Å
266I96.4Very high95.2Very high1 Ų143.6 Ų43.61%0.00523%0.233CC..EExtended strand (participates in β ladder)trans-116.1122.5179.3-53.8-179.4000108.6Y18 L20 P21 A129 S258 V259 V261 I264 D271Y18-I266 HydrophobicContact CD1-CD1 4.19Å; Y18-I266 HydrophobicContact CE1-CD1 3.9Å; L20-I266 HydrophobicContact CD2-CD1 3.92Å; P21-I266 HydrophobicContact CG-CG2 4.49Å; A129-I266 HydrophobicContact CB-CD1 4.1Å; A129-I266 HydrophobicContact CB-CG2 3.73Å; S258-I266 WeakPolarHBondContact CA-O 3.18Å; S258-I266 WeakPolarHBondContact CB-O 3.35Å; V259-I266 HydrophobicContact CG2-CB 4.34Å; V259-I266 PolarHBondContact N-O 3.37Å; V259-I266 PolarHBondContact O-N 3.21Å; V261-I266 HydrophobicContact CB-CD1 4.06Å; V261-I266 HydrophobicContact CG2-CD1 3.7Å; V261-I266 HydrophobicContact CG2-CG1 4.4Å; I264-I266 HydrophobicContact CG2-CG1 4.25Å; I266-D271 HydrophobicContact CG2-CB 3.94Å
267S95.3Very high95.9Very high49 Ų4943.5 Ų43.534%0.34323%0.231SC..EExtended strand (participates in β ladder)trans-67141173.4178.90000110.7D269 D270 D271S267-D269 PolarHBondContact O-N 2.84Å; S267-D269 PolarHBondContact OG-N 2.85Å; S267-D270 CarbonylContact O-C 3.48Å; S267-D270 PolarHBondContact O-N 2.77Å; S267-D271 PolarHBondContact O-N 3.33Å
268R94Very high96.2Very high22 Ų2239 Ų398%0.08320%0.202CC..G310 helixtrans-53.7-38174176.5177.3-59.4-55.5-0.9112.4W232 S233 L254 L255 P257 D270 D271W232-R268 VanDerWaalsContact CD2-NH1 3.29Å; W232-R268 VanDerWaalsContact CE2-NH1 3.3Å; W232-R268 HydrophobicContact CH2-CB 3.87Å; W232-R268 HydrophobicContact CH2-CG 4.49Å; W232-R268 VanDerWaalsContact CH2-CZ 3.45Å; W232-R268 HydrophobicContact CZ2-CB 3.92Å; W232-R268 HydrophobicContact CZ2-CG 4.34Å; S233-R268 PolarHBondContact O-NH1 2.94Å; L254-R268 PolarHBondContact O-NH2 3.08Å; L255-R268 VanDerWaalsContact C-NH2 3.3Å; L255-R268 PolarHBondContact O-NE 3.39Å; L255-R268 PolarHBondContact O-NH2 2.75Å; P257-R268 WeakPolarHBondContact O-CB 3.48Å; P257-R268 PolarHBondContact O-N 3.07Å; R268-D270 PolarHBondContact O-N 3.08Å; R268-D271 PolarHBondContact O-N 2.72Å
269D93.8Very high96.2Very high125 Ų12540.1 Ų40.167%0.66821%0.208SC*.G310 helixtrans-70.1-20.2-177.6-72.3-26.3000112.8K128 S267K128-D269 WeakPolarHBondContact CD-O 3.31Å; K128-D269 WeakPolarHBondContact CE-O 3.39Å; K128-D269 PolarHBondContact NZ-O 2.87Å; S267-D269 PolarHBondContact O-N 2.84Å; S267-D269 PolarHBondContact OG-N 2.85Å
270D96Very high95.9Very high61 Ų6142.3 Ų42.333%0.32623%0.231SC..G310 helixtrans-103.418175.1-77.9-47.6000112.7P21 R22 K128 A129 S267 R268P21-D270 HydrophobicContact CB-CB 4.22Å; R22-D270 IonicContact CZ-OD1 3.31Å; R22-D270 IonicContact NH2-OD1 2.81Å; R22-D270 PolarHBondContact NH2-OD1 3.17Å; K128-D270 WeakPolarHBondContact CB-O 3.35Å; A129-D270 WeakPolarHBondContact CB-O 3.46Å; A129-D270 PolarHBondContact N-O 3.01Å; S267-D270 CarbonylContact O-C 3.48Å; S267-D270 PolarHBondContact O-N 2.77Å; R268-D270 PolarHBondContact O-N 3.08Å
271D96.8Very high95.4Very high12 Ų1244.8 Ų44.86%0.06425%0.249CC..BIsolated β-bridgetrans-129.1124.8-178.2-168.30.5000112.3Y18 A129 W232 I266 S267 R268 S273Y18-D271 PolarHBondContact OH-OD2 2.88Å; A129-D271 HydrophobicContact CB-CB 4.23Å; W232-D271 PolarHBondContact NE1-OD2 3.34Å; I266-D271 HydrophobicContact CG2-CB 3.94Å; S267-D271 PolarHBondContact O-N 3.33Å; R268-D271 PolarHBondContact O-N 2.72Å; D271-S273 WeakPolarHBondContact OD1-CB 3.44Å; D271-S273 PolarHBondContact OD1-N 2.96Å; D271-S273 PolarHBondContact OD1-OG 3.44Å; D271-S273 PolarHBondContact OD2-OG 2.86Å
272T96.7Very high95.2Very high40 Ų4050.7 Ų50.725%0.24529%0.285CS..  trans-101.7-4.4176.364.90000113T106 K128 A129 R274T106-T272 WeakPolarHBondContact CB-O 3.47Å; T106-T272 PolarHBondContact OG1-OG1 2.85Å; T106-T272 VanDerWaalsContact OG1-OG1 3.08Å; K128-T272 HydrophobicContact CB-CG2 3.79Å; K128-T272 HydrophobicContact CD-CG2 4Å; K128-T272 HydrophobicContact CG-CG2 4.49Å; A129-T272 PolarHBondContact O-N 3.41Å; A129-T272 PolarHBondContact O-OG1 3.34Å; T272-R274 PolarHBondContact O-NH1 3.19Å
273S97.2Very high95.2Very high1 Ų149.5 Ų49.51%0.00728%0.278CS..  trans-62.9148.417873.90000111.2Y18 D271Y18-S273 PolarHBondContact OH-OG 3.38Å; D271-S273 WeakPolarHBondContact OD1-CB 3.44Å; D271-S273 PolarHBondContact OD1-N 2.96Å; D271-S273 PolarHBondContact OD1-OG 3.44Å; D271-S273 PolarHBondContact OD2-OG 2.86Å
274R97.6Very high95.4Very high28 Ų2842.3 Ų42.311%0.10625%0.249CC..  trans-137122.7173.2-58.9159.2-178.194.7-4.3107.1W232 T272 S289 N290 D292W232-R274 VanDerWaalsContact O-CA 3.32Å; W232-R274 WeakPolarHBondContact O-CA 3.34Å; T272-R274 PolarHBondContact O-NH1 3.19Å; R274-S289 WeakPolarHBondContact CB-O 3.44Å; R274-S289 PolarHBondContact O-N 3Å; R274-N290 VanDerWaalsContact CD-C 3.45Å; R274-D292 WeakPolarHBondContact CD-OD1 3.32Å; R274-D292 WeakPolarHBondContact CG-OD1 3.18Å; R274-D292 IonicContact CZ-OD1 3.79Å; R274-D292 IonicContact CZ-OD2 3.51Å; R274-D292 IonicContact NE-OD1 3.53Å; R274-D292 PolarHBondContact NE-OD1 2.89Å; R274-D292 IonicContact NE-OD2 3.45Å; R274-D292 PolarHBondContact NE-OD2 3.29Å; R274-D292 VanDerWaalsContact NE-OD2 3.13Å; R274-D292 IonicContact NH2-OD1 2.81Å; R274-D292 IonicContact NH2-OD2 3.36Å; R274-D292 PolarHBondContact NH2-OD2 3.04Å
275W98.4Very high95.5Very high0 Ų039.6 Ų39.60%024%0.235CC..EExtended strand (participates in β ladder)trans-151.5159.6-177.555.2-97000110.5Y18 L131 W232 L254 V259 I277 F286 C287 F316 V319 A320Y18-W275 AromaticContact CE2-NE1 3.99Å; L131-W275 HydrophobicContact CD2-CB 4.18Å; W232-W275 HydrophobicContact CB-CD2 3.7Å; W232-W275 HydrophobicContact CB-CE3 4.16Å; W232-W275 HydrophobicContact CB-CG 4.22Å; W232-W275 HydrophobicContact CB-CH2 3.98Å; W232-W275 HydrophobicContact CB-CZ2 3.5Å; W232-W275 HydrophobicContact CB-CZ3 4.28Å; W232-W275 AromaticContact CD1-CD1 3.78Å; W232-W275 AromaticContact CD1-CE2 3.8Å; W232-W275 AromaticContact CD1-NE1 3.22Å; W232-W275 HydrophobicContact CD2-CZ2 4.38Å; W232-W275 HydrophobicContact CG-CD2 4.43Å; W232-W275 AromaticContact CG-CE2 3.66Å; W232-W275 AromaticContact CG-CZ2 3.79Å; W232-W275 HydrophobicContact CG-CZ2 3.79Å; W232-W275 AromaticContact CG-NE1 3.58Å; W232-W275 PolarHBondContact N-O 2.98Å; W232-W275 PolarHBondContact O-N 3.38Å; L254-W275 HydrophobicContact CD1-CH2 3.6Å; L254-W275 HydrophobicContact CD1-CZ2 4.36Å; L254-W275 HydrophobicContact CD1-CZ3 3.92Å; V259-W275 HydrophobicContact CG1-CZ2 4.08Å; W275-I277 HydrophobicContact CE3-CG2 4.33Å; W275-I277 HydrophobicContact CZ3-CD1 4.49Å; W275-I277 HydrophobicContact CZ3-CG1 4.44Å; W275-I277 HydrophobicContact CZ3-CG2 4.23Å; W275-F286 HydrophobicContact CB-CE2 3.83Å; W275-F286 HydrophobicContact CB-CZ 4.21Å; W275-F286 HydrophobicContact CD2-CE2 4.38Å; W275-F286 HydrophobicContact CE3-CE2 4.38Å; W275-F286 HydrophobicContact CG-CE2 4.19Å; W275-C287 CarbonylContact C-O 3.58Å; W275-C287 WeakPolarHBondContact CA-O 3.46Å; W275-C287 WeakPolarHBondContact CB-O 3.28Å; W275-F316 AromaticContact CD2-CD1 3.93Å; W275-F316 HydrophobicContact CD2-CD1 3.93Å; W275-F316 HydrophobicContact CD2-CE1 4.34Å; W275-F316 HydrophobicContact CE3-CD1 4.03Å; W275-F316 HydrophobicContact CG-CD1 4.46Å; W275-F316 HydrophobicContact CG-CE1 4.45Å; W275-F316 HydrophobicContact CH2-CD1 4.35Å; W275-F316 HydrophobicContact CZ2-CD1 4.24Å; W275-F316 HydrophobicContact CZ3-CB 4.34Å; W275-F316 HydrophobicContact CZ3-CD1 4.25Å; W275-V319 HydrophobicContact CH2-CG1 4.41Å; W275-V319 HydrophobicContact CZ2-CG1 3.91Å; W275-A320 HydrophobicContact CH2-CB 4.01Å
276A98.4Very high95.6Very high0 Ų035.3 Ų35.30%021%0.209CC..EExtended strand (participates in β ladder)trans-138.5152176.900000110.2Y217 L229 N230 V231 C287Y217-A276 HydrophobicContact CD1-CB 4.35Å; Y217-A276 HydrophobicContact CE1-CB 4.07Å; L229-A276 HydrophobicContact CD2-CB 4.45Å; N230-A276 WeakPolarHBondContact O-CA 3.24Å; V231-A276 HydrophobicContact CG2-CB 4.05Å; A276-C287 HydrophobicContact CB-CB 4.36Å; A276-C287 PolarHBondContact N-O 3.27Å; A276-C287 WeakPolarHBondContact O-CB 3.27Å; A276-C287 PolarHBondContact O-N 3.3Å
277I98.3Very high95.7Very high0 Ų035.3 Ų35.30%021%0.209CC..EExtended strand (participates in β ladder)trans-125.8144.417056.6179.6000109.3L229 N230 W275 L285 F286 R313 F316 Q317L229-I277 CarbonylContact C-O 3.57Å; L229-I277 WeakPolarHBondContact CA-O 3.37Å; N230-I277 HydrophobicContact CB-CD1 4.49Å; N230-I277 HydrophobicContact CB-CG1 3.93Å; N230-I277 PolarHBondContact N-O 2.81Å; N230-I277 PolarHBondContact O-N 2.79Å; W275-I277 HydrophobicContact CE3-CG2 4.33Å; W275-I277 HydrophobicContact CZ3-CD1 4.49Å; W275-I277 HydrophobicContact CZ3-CG1 4.44Å; W275-I277 HydrophobicContact CZ3-CG2 4.23Å; I277-L285 VanDerWaalsContact CA-O 3.31Å; I277-L285 WeakPolarHBondContact CA-O 3.38Å; I277-F286 HydrophobicContact CG2-CD2 4Å; I277-R313 HydrophobicContact CB-CG 4.08Å; I277-R313 HydrophobicContact CG2-CG 4.3Å; I277-F316 HydrophobicContact CG2-CB 3.67Å; I277-Q317 HydrophobicContact CD1-CB 3.91Å; I277-Q317 HydrophobicContact CD1-CG 4.48Å; I277-Q317 VanDerWaalsContact CD1-OE1 3.24Å
278T98Very high95.9Very high0 Ų033.3 Ų33.30%020%0.195CC..EExtended strand (participates in β ladder)trans-72.7150.2172.550.10000112A227 G228 L229 L283 L285A227-T278 HydrophobicContact CB-CG2 3.8Å; G228-T278 CarbonylContact O-C 3.5Å; G228-T278 WeakPolarHBondContact O-CA 3.16Å; L229-T278 HydrophobicContact CD2-CG2 3.74Å; T278-L283 WeakPolarHBondContact CB-O 3.45Å; T278-L283 PolarHBondContact OG1-O 3.19Å; T278-L285 HydrophobicContact CG2-CB 3.8Å; T278-L285 HydrophobicContact CG2-CD1 3.93Å; T278-L285 HydrophobicContact CG2-CG 3.89Å; T278-L285 PolarHBondContact N-O 3.22Å; T278-L285 VanDerWaalsContact N-O 3.15Å; T278-L285 PolarHBondContact OG1-N 2.93Å
279T94.1Very high96.1Very high46 Ų4632.6 Ų32.628%0.28219%0.193SC..SBendtrans-94.2143.7171.163.20000110.2G228G228-T279 WeakPolarHBondContact CA-OG1 3.23Å; G228-T279 PolarHBondContact O-N 2.68Å; G228-T279 PolarHBondContact O-OG1 3.05Å
280G89.7Confident96.2Very high47 Ų4727.5 Ų27.549%0.48517%0.166SC..SBendtrans82.4-176.3-173.900000113.6
281N88.1Confident96.2Very high145 Ų14524.7 Ų24.778%0.77515%0.151SC*.SBendtrans-112.5-3.6-171.4-65.3-21.3000113.9
282T90.3Very high96.1Very high123 Ų12324.1 Ų24.176%0.75515%0.148SC*.SBendtrans-70.6-34.1-174.248.90000113.1
283L95.9Very high96Very high21 Ų2122.3 Ų22.311%0.1114%0.137CC..SBendtrans-146.685.1178.7-172.371.7000109A225 T278 L285 E308A225-L283 HydrophobicContact CB-CD2 3.96Å; A225-L283 WeakPolarHBondContact O-CD2 3.26Å; T278-L283 WeakPolarHBondContact CB-O 3.45Å; T278-L283 PolarHBondContact OG1-O 3.19Å; L283-L285 HydrophobicContact CD1-CD2 4.33Å; L283-L285 HydrophobicContact CD2-CD1 3.86Å; L283-L285 HydrophobicContact CD2-CD2 4.44Å; L283-L285 HydrophobicContact CD2-CG 4.2Å; L283-L285 HydrophobicContact CG-CD1 4.16Å; L283-L285 HydrophobicContact CG-CD2 3.97Å; L283-L285 HydrophobicContact CG-CG 3.93Å; L283-L285 PolarHBondContact O-N 3.24Å; L283-L285 VanDerWaalsContact O-N 3.15Å; L283-E308 HydrophobicContact CD1-CG 4.36Å; L283-E308 WeakPolarHBondContact CD1-OE2 3.39Å
284P96.8Very high95.8Very high21 Ų2125.4 Ų25.414%0.13615%0.148CC..  trans-79.599-173.731.3-33.6000111.3E308 N309 A310 R313P284-E308 WeakPolarHBondContact O-CA 3.5Å; P284-N309 PolarHBondContact O-N 2.93Å; P284-A310 HydrophobicContact CB-CB 4.18Å; P284-A310 HydrophobicContact CG-CB 4Å; P284-R313 HydrophobicContact CB-CB 4.27Å; P284-R313 HydrophobicContact CB-CG 4.45Å
285L98.2Very high95.6Very high0 Ų031.9 Ų31.90%017%0.173CC..EExtended strand (participates in β ladder)trans-109.7133.8-178.6-54.3-178.7000110.3A225 I277 T278 L283 C306 I307 E308 R313A225-L285 HydrophobicContact CB-CD1 4.5Å; I277-L285 VanDerWaalsContact CA-O 3.31Å; I277-L285 WeakPolarHBondContact CA-O 3.38Å; T278-L285 HydrophobicContact CG2-CB 3.8Å; T278-L285 HydrophobicContact CG2-CD1 3.93Å; T278-L285 HydrophobicContact CG2-CG 3.89Å; T278-L285 PolarHBondContact N-O 3.22Å; T278-L285 VanDerWaalsContact N-O 3.15Å; T278-L285 PolarHBondContact OG1-N 2.93Å; L283-L285 HydrophobicContact CD1-CD2 4.33Å; L283-L285 HydrophobicContact CD2-CD1 3.86Å; L283-L285 HydrophobicContact CD2-CD2 4.44Å; L283-L285 HydrophobicContact CD2-CG 4.2Å; L283-L285 HydrophobicContact CG-CD1 4.16Å; L283-L285 HydrophobicContact CG-CD2 3.97Å; L283-L285 HydrophobicContact CG-CG 3.93Å; L283-L285 PolarHBondContact O-N 3.24Å; L283-L285 VanDerWaalsContact O-N 3.15Å; L285-C306 HydrophobicContact CB-CB 4.16Å; L285-C306 HydrophobicContact CD1-CB 4.2Å; L285-C306 HydrophobicContact CD2-CB 4.42Å; L285-C306 HydrophobicContact CG-CB 4.5Å; L285-I307 WeakPolarHBondContact CA-O 3.26Å; L285-E308 HydrophobicContact CD2-CB 3.75Å; L285-E308 HydrophobicContact CD2-CG 3.97Å; L285-R313 WeakPolarHBondContact O-CG 3.21Å
286F98.2Very high95.2Very high0 Ų035.1 Ų35.10%020%0.195CC..EExtended strand (participates in β ladder)trans-102.9130.5154167.8-104.8000108.7I16 L131 M133 W275 I277 V288 C306 I307 L312 F316I16-F286 HydrophobicContact CD1-CD1 3.73Å; I16-F286 HydrophobicContact CD1-CE1 3.44Å; I16-F286 VanDerWaalsContact CD1-CE1 3.44Å; I16-F286 HydrophobicContact CD1-CZ 4.49Å; I16-F286 HydrophobicContact CG1-CE1 4.25Å; L131-F286 HydrophobicContact CD2-CZ 4.17Å; M133-F286 HydrophobicContact CE-CD1 4.02Å; M133-F286 HydrophobicContact CE-CE1 3.64Å; W275-F286 HydrophobicContact CB-CE2 3.83Å; W275-F286 HydrophobicContact CB-CZ 4.21Å; W275-F286 HydrophobicContact CD2-CE2 4.38Å; W275-F286 HydrophobicContact CE3-CE2 4.38Å; W275-F286 HydrophobicContact CG-CE2 4.19Å; I277-F286 HydrophobicContact CG2-CD2 4Å; F286-V288 HydrophobicContact CE1-CG2 3.88Å; F286-V288 HydrophobicContact CZ-CG2 3.98Å; F286-C306 CarbonylContact O-C 3.6Å; F286-C306 WeakPolarHBondContact O-CA 3.35Å; F286-I307 PolarHBondContact N-O 3.07Å; F286-I307 VanDerWaalsContact N-O 3.07Å; F286-I307 PolarHBondContact O-N 3.23Å; F286-L312 HydrophobicContact CB-CD2 3.89Å; F286-L312 HydrophobicContact CB-CG 3.74Å; F286-L312 HydrophobicContact CD1-CD1 4.41Å; F286-L312 HydrophobicContact CD1-CD2 3.77Å; F286-L312 HydrophobicContact CD1-CG 4.02Å; F286-L312 HydrophobicContact CG-CD2 4.17Å; F286-L312 HydrophobicContact CG-CG 4.03Å; F286-F316 HydrophobicContact CD1-CD2 4.41Å; F286-F316 HydrophobicContact CD1-CE2 4.29Å; F286-F316 HydrophobicContact CD2-CB 3.79Å; F286-F316 AromaticContact CD2-CD1 3.84Å; F286-F316 HydrophobicContact CD2-CD1 3.84Å; F286-F316 AromaticContact CD2-CD2 3.42Å; F286-F316 HydrophobicContact CD2-CD2 3.42Å; F286-F316 VanDerWaalsContact CD2-CD2 3.42Å; F286-F316 HydrophobicContact CD2-CE1 4.26Å; F286-F316 AromaticContact CD2-CE2 3.9Å; F286-F316 HydrophobicContact CD2-CE2 3.9Å; F286-F316 AromaticContact CD2-CG 3.38Å; F286-F316 HydrophobicContact CD2-CG 3.38Å; F286-F316 HydrophobicContact CD2-CZ 4.29Å; F286-F316 HydrophobicContact CE1-CD2 4.4Å; F286-F316 AromaticContact CE1-CE2 3.92Å; F286-F316 HydrophobicContact CE1-CE2 3.92Å; F286-F316 HydrophobicContact CE1-CZ 4.08Å; F286-F316 HydrophobicContact CE2-CB 4.11Å; F286-F316 AromaticContact CE2-CD1 3.25Å; F286-F316 HydrophobicContact CE2-CD1 3.25Å; F286-F316 AromaticContact CE2-CD2 3.43Å; F286-F316 HydrophobicContact CE2-CD2 3.43Å; F286-F316 VanDerWaalsContact CE2-CD2 3.43Å; F286-F316 AromaticContact CE2-CE1 3.32Å; F286-F316 HydrophobicContact CE2-CE1 3.32Å; F286-F316 AromaticContact CE2-CE2 3.51Å; F286-F316 HydrophobicContact CE2-CE2 3.51Å; F286-F316 AromaticContact CE2-CG 3.29Å; F286-F316 HydrophobicContact CE2-CG 3.29Å; F286-F316 AromaticContact CE2-CZ 3.45Å; F286-F316 HydrophobicContact CE2-CZ 3.45Å; F286-F316 VanDerWaalsContact CE2-CZ 3.45Å; F286-F316 AromaticContact CG-CD2 3.93Å; F286-F316 HydrophobicContact CG-CD2 3.93Å; F286-F316 HydrophobicContact CG-CE2 4.26Å; F286-F316 HydrophobicContact CG-CG 4.32Å; F286-F316 HydrophobicContact CZ-CD1 4Å; F286-F316 AromaticContact CZ-CD2 3.92Å; F286-F316 HydrophobicContact CZ-CD2 3.92Å; F286-F316 AromaticContact CZ-CE1 3.57Å; F286-F316 HydrophobicContact CZ-CE1 3.57Å; F286-F316 AromaticContact CZ-CE2 3.49Å; F286-F316 HydrophobicContact CZ-CE2 3.49Å; F286-F316 VanDerWaalsContact CZ-CE2 3.49Å; F286-F316 HydrophobicContact CZ-CG 4.15Å; F286-F316 AromaticContact CZ-CZ 3.3Å; F286-F316 HydrophobicContact CZ-CZ 3.3Å
287C98.7Very high95Very high1 Ų136.1 Ų36.11%0.00720%0.2CC..EExtended strand (participates in β ladder)trans-127.3137-174.2-53.40000112.3W275 A276 V304 V305 C306W275-C287 CarbonylContact C-O 3.58Å; W275-C287 WeakPolarHBondContact CA-O 3.46Å; W275-C287 WeakPolarHBondContact CB-O 3.28Å; A276-C287 HydrophobicContact CB-CB 4.36Å; A276-C287 PolarHBondContact N-O 3.27Å; A276-C287 WeakPolarHBondContact O-CB 3.27Å; A276-C287 PolarHBondContact O-N 3.3Å; C287-V304 HydrophobicContact CB-CG1 3.54Å; C287-V305 CarbonylContact C-O 3.57Å; C287-V305 VanDerWaalsContact CA-O 3.23Å; C287-V305 WeakPolarHBondContact CA-O 3.34Å; C287-C306 HydrophobicContact CB-CB 4Å; C287-C306 WeakPolarHBondContact CB-SG 3.12Å; C287-C306 WeakPolarHBondContact SG-CB 3.46Å; C287-C306 CovalentContact SG-SG 2.03Å; C287-C306 PolarHBondContact SG-SG 2.85Å
288V98.5Very high94.8Very high7 Ų737.6 Ų37.64%0.04221%0.209CC..EExtended strand (participates in β ladder)trans-97.1140.3165178.70000108.9L131 M133 F286 V304 V305L131-V288 HydrophobicContact CD2-CB 4.41Å; L131-V288 HydrophobicContact CD2-CG1 4.17Å; L131-V288 HydrophobicContact CD2-CG2 3.55Å; L131-V288 HydrophobicContact CG-CG2 4.21Å; M133-V288 HydrophobicContact CB-CG2 4.17Å; M133-V288 HydrophobicContact CE-CB 4.27Å; M133-V288 HydrophobicContact CE-CG2 3.37Å; M133-V288 HydrophobicContact SD-CB 4.27Å; M133-V288 HydrophobicContact SD-CG2 3.9Å; F286-V288 HydrophobicContact CE1-CG2 3.88Å; F286-V288 HydrophobicContact CZ-CG2 3.98Å; V288-V304 CarbonylContact O-C 3.58Å; V288-V304 WeakPolarHBondContact O-CA 3.37Å; V288-V305 PolarHBondContact N-O 3.13Å; V288-V305 PolarHBondContact O-N 2.7Å
289S98Very high94.7Very high7 Ų739.2 Ų39.25%0.04922%0.223CC..EExtended strand (participates in β ladder)trans-132.2165177.9-170.80000111.7Y217 R274 A291 G303 V304Y217-S289 WeakPolarHBondContact OH-CB 3.44Å; Y217-S289 PolarHBondContact OH-OG 2.79Å; R274-S289 WeakPolarHBondContact CB-O 3.44Å; R274-S289 PolarHBondContact O-N 3Å; S289-A291 PolarHBondContact OG-N 2.96Å; S289-G303 WeakPolarHBondContact CA-O 3.34Å; S289-G303 PolarHBondContact OG-O 3.29Å; S289-V304 WeakPolarHBondContact OG-CG2 3.08Å
290N96.5Very high94.7Very high17 Ų1737.7 Ų37.79%0.09121%0.213CC..SBendtrans-1091.6165.158.930000112.2P88 S89 R274 S302 G303P88-N290 HydrophobicContact CB-CB 4.31Å; P88-N290 WeakPolarHBondContact CB-O 3.34Å; P88-N290 HydrophobicContact CG-CB 4.06Å; P88-N290 WeakPolarHBondContact CG-O 3.11Å; S89-N290 PolarHBondContact OG-ND2 3.14Å; R274-N290 VanDerWaalsContact CD-C 3.45Å; N290-S302 WeakPolarHBondContact OD1-CA 3.45Å; N290-S302 WeakPolarHBondContact OD1-CB 3.11Å; N290-G303 PolarHBondContact N-O 2.82Å; N290-G303 PolarHBondContact ND2-N 3.19Å; N290-G303 PolarHBondContact OD1-N 3Å; N290-G303 PolarHBondContact OD1-O 2.9Å
291A95.8Very high95.1Very high2 Ų235.6 Ų35.62%0.01719%0.191CC..  trans-97.2134.2-178.700000112.7I216 Y217 S289I216-A291 HydrophobicContact CG2-CB 3.67Å; Y217-A291 HydrophobicContact CE2-CB 3.79Å; Y217-A291 WeakPolarHBondContact CE2-O 3.37Å; Y217-A291 PolarHBondContact OH-O 3.41Å; S289-A291 PolarHBondContact OG-N 2.96Å
292D95.3Very high95.5Very high0 Ų028.7 Ų28.70%015%0.154CC..  trans-89.9155.6165.7-67.8-50.6000111.5S233 S234 R274 R294 H297S233-D292 WeakPolarHBondContact CB-OD1 3.48Å; S234-D292 WeakPolarHBondContact CB-OD1 3.14Å; S234-D292 PolarHBondContact N-OD1 3.05Å; R274-D292 WeakPolarHBondContact CD-OD1 3.32Å; R274-D292 WeakPolarHBondContact CG-OD1 3.18Å; R274-D292 IonicContact CZ-OD1 3.79Å; R274-D292 IonicContact CZ-OD2 3.51Å; R274-D292 IonicContact NE-OD1 3.53Å; R274-D292 PolarHBondContact NE-OD1 2.89Å; R274-D292 IonicContact NE-OD2 3.45Å; R274-D292 PolarHBondContact NE-OD2 3.29Å; R274-D292 VanDerWaalsContact NE-OD2 3.13Å; R274-D292 IonicContact NH2-OD1 2.81Å; R274-D292 IonicContact NH2-OD2 3.36Å; R274-D292 PolarHBondContact NH2-OD2 3.04Å; D292-R294 HydrophobicContact CB-CB 4.42Å; D292-R294 HydrophobicContact CB-CG 3.96Å; D292-R294 VanDerWaalsContact CB-NE 3.3Å; D292-R294 PolarHBondContact O-N 2.84Å; D292-R294 IonicContact OD2-CZ 3.76Å; D292-R294 IonicContact OD2-NE 3.2Å; D292-R294 PolarHBondContact OD2-NE 3Å; D292-R294 IonicContact OD2-NH2 3.67Å; D292-R294 PolarHBondContact OD2-NH2 3.14Å; D292-H297 PolarHBondContact N-ND1 3.29Å; D292-H297 WeakPolarHBondContact O-CB 3.34Å; D292-H297 IonicContact OD2-CE1 2.67Å; D292-H297 PolarHBondContact OD2-CE1 2.8Å; D292-H297 VanDerWaalsContact OD2-CE1 3.31Å; D292-H297 IonicContact OD2-NE2 2.8Å
293R94.6Very high95.9Very high3 Ų322.9 Ų22.91%0.01112%0.119CC..SBendtrans-76.459.7171.8-67.1-70.8-60138.1-7111.3D215 Y217 V231 S233 K240 L241 P242 N253D215-R293 IonicContact OD1-NH1 3Å; D215-R293 PolarHBondContact OD1-NH1 2.87Å; D215-R293 IonicContact OD2-CZ 3.33Å; D215-R293 IonicContact OD2-NH1 2.77Å; D215-R293 PolarHBondContact OD2-NH1 3.24Å; Y217-R293 VanDerWaalsContact CD2-CD 3.49Å; Y217-R293 HydrophobicContact CD2-CG 4.38Å; Y217-R293 HydrophobicContact CE2-CG 4.37Å; V231-R293 HydrophobicContact CB-CG 4.12Å; V231-R293 HydrophobicContact CG1-CG 3.68Å; S233-R293 WeakPolarHBondContact OG-CG 3.15Å; S233-R293 PolarHBondContact OG-N 3.02Å; K240-R293 CarbonylContact C-O 3.48Å; K240-R293 WeakPolarHBondContact CA-O 3.41Å; L241-R293 PolarHBondContact N-O 2.87Å; P242-R293 PolarHBondContact O-NH2 2.97Å; N253-R293 VanDerWaalsContact OD1-CG 3.25Å; N253-R293 WeakPolarHBondContact OD1-CG 3.45Å; N253-R293 PolarHBondContact OD1-NE 3.25Å
294R93.1Very high96Very high65 Ų6522 Ų2225%0.24511%0.114CC..BIsolated β-bridgetrans-129.7146-176.2-63.9-175.3-68171.2-5.8111.4M239 D292 S296 H297M239-R294 WeakPolarHBondContact O-CA 3.42Å; D292-R294 HydrophobicContact CB-CB 4.42Å; D292-R294 HydrophobicContact CB-CG 3.96Å; D292-R294 VanDerWaalsContact CB-NE 3.3Å; D292-R294 PolarHBondContact O-N 2.84Å; D292-R294 IonicContact OD2-CZ 3.76Å; D292-R294 IonicContact OD2-NE 3.2Å; D292-R294 PolarHBondContact OD2-NE 3Å; D292-R294 IonicContact OD2-NH2 3.67Å; D292-R294 PolarHBondContact OD2-NH2 3.14Å; R294-S296 PolarHBondContact O-N 3.37Å; R294-H297 PolarHBondContact NH2-NE2 3.32Å; R294-H297 PolarHBondContact O-N 3.48Å
295R92Very high96.1Very high165 Ų16521.1 Ų21.162%0.62311%0.109SC*.G310 helixtrans-59.1-35.5178.9-174176.3179.91760.8112.5M239 L241 H297 T298M239-R295 HydrophobicContact CB-CB 4.2Å; M239-R295 PolarHBondContact O-N 3.32Å; M239-R295 VanDerWaalsContact O-N 3.11Å; L241-R295 HydrophobicContact CD2-CB 4.34Å; R295-H297 PolarHBondContact O-N 2.82Å; R295-T298 PolarHBondContact O-N 2.9Å; R295-T298 PolarHBondContact O-OG1 3.13Å
296S91.7Very high96.2Very high68 Ų6821.1 Ų21.148%0.47611%0.109SC..G310 helixtrans-62-30.1176.251.70000113R294 T298 A299R294-S296 PolarHBondContact O-N 3.37Å; S296-T298 VanDerWaalsContact C-N 3.26Å; S296-T298 PolarHBondContact O-N 3.32Å; S296-A299 PolarHBondContact O-N 3.22Å
297H94Very high96.1Very high21 Ų2121.1 Ų21.110%0.09711%0.109CC..G310 helixtrans-77.6-9.7-178.3-79.5-121.9000113.9K208 D292 R294 R295 V300K208-H297 PolarHBondContact NZ-O 2.82Å; D292-H297 PolarHBondContact N-ND1 3.29Å; D292-H297 WeakPolarHBondContact O-CB 3.34Å; D292-H297 IonicContact OD2-CE1 2.67Å; D292-H297 PolarHBondContact OD2-CE1 2.8Å; D292-H297 VanDerWaalsContact OD2-CE1 3.31Å; D292-H297 IonicContact OD2-NE2 2.8Å; R294-H297 PolarHBondContact NH2-NE2 3.32Å; R294-H297 PolarHBondContact O-N 3.48Å; R295-H297 PolarHBondContact O-N 2.82Å; H297-V300 HydrophobicContact CB-CG2 4.28Å
298T94.6Very high96Very high30 Ų3024 Ų2418%0.18412%0.122CC..G310 helixtrans-70.2-26169.270.70000111.2H213 L214 D215 L241 R295 S296H213-T298 CarbonylContact C-O 3.6Å; H213-T298 WeakPolarHBondContact CA-O 3.44Å; L214-T298 PolarHBondContact N-O 3.16Å; L214-T298 WeakPolarHBondContact O-CA 3.44Å; D215-T298 HydrophobicContact CB-CG2 4.35Å; L241-T298 HydrophobicContact CD1-CG2 3.98Å; R295-T298 PolarHBondContact O-N 2.9Å; R295-T298 PolarHBondContact O-OG1 3.13Å; S296-T298 VanDerWaalsContact C-N 3.26Å; S296-T298 PolarHBondContact O-N 3.32Å
299A94.4Very high95.8Very high35 Ų3524.1 Ų24.129%0.28912%0.122SC..G310 helixtrans-104.314.8-175.900000114.5R210 S296R210-A299 WeakPolarHBondContact CG-O 3.45Å; R210-A299 PolarHBondContact NE-O 2.83Å; S296-A299 PolarHBondContact O-N 3.22Å
300V95.3Very high95.7Very high14 Ų1425.7 Ų25.79%0.08514%0.136CC..SBendtrans-118.6160.6167.1-570000108.2K208 H297K208-V300 PolarHBondContact NZ-O 2.94Å; H297-V300 HydrophobicContact CB-CG2 4.28Å
301S97.3Very high95.7Very high2 Ų228.2 Ų28.21%0.01415%0.147CC..  trans-71.7158.4170.753.50000110.8S87 P88 Q152 K208S87-S301 WeakPolarHBondContact CB-OG 3.18Å; S87-S301 PolarHBondContact OG-OG 3.4Å; P88-S301 WeakPolarHBondContact CD-O 3.27Å; Q152-S301 WeakPolarHBondContact O-CB 3.22Å; Q152-S301 PolarHBondContact O-OG 3.21Å; K208-S301 CarbonylContact O-C 3.41Å; K208-S301 VanDerWaalsContact O-CA 3.26Å; K208-S301 WeakPolarHBondContact O-CA 3.39Å; K208-S301 VanDerWaalsContact O-CB 3.31Å; K208-S301 WeakPolarHBondContact O-CB 3.35Å
302S97.2Very high95.7Very high0 Ų028.1 Ų28.10%015%0.146CC..EExtended strand (participates in β ladder)trans-160.5165176.263.30000113.2S207 K208 I216 N290S207-S302 WeakPolarHBondContact CA-O 3.41Å; K208-S302 WeakPolarHBondContact CE-OG 3.05Å; K208-S302 VanDerWaalsContact CG-OG 3.27Å; K208-S302 WeakPolarHBondContact CG-OG 3.04Å; K208-S302 PolarHBondContact N-O 3.19Å; K208-S302 PolarHBondContact NZ-OG 2.61Å; K208-S302 PolarHBondContact O-N 3.03Å; I216-S302 WeakPolarHBondContact CD1-OG 3.2Å; N290-S302 WeakPolarHBondContact OD1-CA 3.45Å; N290-S302 WeakPolarHBondContact OD1-CB 3.11Å
303G98.2Very high95.8Very high2 Ų229.6 Ų29.62%0.02115%0.152CC..EExtended strand (participates in β ladder)trans-133.4153.3176.700000112.8Y206 S289 N290Y206-G303 CarbonylContact O-C 3.37Å; Y206-G303 VanDerWaalsContact O-CA 3.31Å; Y206-G303 WeakPolarHBondContact O-CA 3.18Å; S289-G303 WeakPolarHBondContact CA-O 3.34Å; S289-G303 PolarHBondContact OG-O 3.29Å; N290-G303 PolarHBondContact N-O 2.82Å; N290-G303 PolarHBondContact ND2-N 3.19Å; N290-G303 PolarHBondContact OD1-N 3Å; N290-G303 PolarHBondContact OD1-O 2.9Å
304V98.7Very high95.9Very high1 Ų134.7 Ų34.71%0.00618%0.176CC..EExtended strand (participates in β ladder)trans-132.8125.1168.6-178.20000107.2L205 Y206 I216 Y217 V221 C287 V288 S289L205-V304 WeakPolarHBondContact CA-O 3.34Å; Y206-V304 HydrophobicContact CD2-CB 4.36Å; Y206-V304 HydrophobicContact CD2-CG1 4.45Å; Y206-V304 PolarHBondContact N-O 3.11Å; Y206-V304 PolarHBondContact O-N 2.74Å; I216-V304 HydrophobicContact CD1-CG2 3.87Å; I216-V304 HydrophobicContact CG1-CG2 4.04Å; I216-V304 HydrophobicContact CG2-CG2 4.09Å; Y217-V304 HydrophobicContact CD1-CG2 4.48Å; Y217-V304 HydrophobicContact CE1-CG2 4.09Å; V221-V304 HydrophobicContact CG2-CB 4.16Å; V221-V304 HydrophobicContact CG2-CG1 4.41Å; V221-V304 HydrophobicContact CG2-CG2 4.02Å; C287-V304 HydrophobicContact CB-CG1 3.54Å; V288-V304 CarbonylContact O-C 3.58Å; V288-V304 WeakPolarHBondContact O-CA 3.37Å; S289-V304 WeakPolarHBondContact OG-CG2 3.08Å
305V98.6Very high96Very high4 Ų432.9 Ų32.92%0.02417%0.171CC..EExtended strand (participates in β ladder)trans-120.6121-178.5-177.40000107.8W102 L104 M133 I135 I203 R204 L205 C287 V288W102-V305 HydrophobicContact CH2-CB 4.41Å; W102-V305 HydrophobicContact CH2-CG1 4.1Å; W102-V305 HydrophobicContact CH2-CG2 3.44Å; W102-V305 VanDerWaalsContact CH2-CG2 3.44Å; W102-V305 HydrophobicContact CZ2-CG2 4.2Å; W102-V305 HydrophobicContact CZ3-CG1 3.8Å; W102-V305 HydrophobicContact CZ3-CG2 4.05Å; L104-V305 HydrophobicContact CD1-CB 3.84Å; L104-V305 HydrophobicContact CD1-CG1 3.91Å; L104-V305 HydrophobicContact CD1-CG2 3.67Å; M133-V305 HydrophobicContact SD-CG1 4.37Å; I135-V305 HydrophobicContact CD1-CG1 3.74Å; I203-V305 HydrophobicContact CG2-CG1 4.19Å; R204-V305 CarbonylContact O-C 3.03Å; R204-V305 WeakPolarHBondContact O-CA 3.15Å; L205-V305 HydrophobicContact CG-CG1 4.44Å; L205-V305 HydrophobicContact CG-CG2 4.38Å; C287-V305 CarbonylContact C-O 3.57Å; C287-V305 VanDerWaalsContact CA-O 3.23Å; C287-V305 WeakPolarHBondContact CA-O 3.34Å; V288-V305 PolarHBondContact N-O 3.13Å; V288-V305 PolarHBondContact O-N 2.7Å
306C98.6Very high96.3Very high0 Ų025 Ų250%014%0.141CC..EExtended strand (participates in β ladder)trans-120.5144.3-170.7-54.20000111.8I203 R204 L285 F286 C287I203-C306 CarbonylContact C-O 3.57Å; I203-C306 WeakPolarHBondContact CA-O 3.45Å; R204-C306 HydrophobicContact CB-CB 4.26Å; R204-C306 PolarHBondContact N-O 2.87Å; R204-C306 PolarHBondContact O-N 2.93Å; L285-C306 HydrophobicContact CB-CB 4.16Å; L285-C306 HydrophobicContact CD1-CB 4.2Å; L285-C306 HydrophobicContact CD2-CB 4.42Å; L285-C306 HydrophobicContact CG-CB 4.5Å; F286-C306 CarbonylContact O-C 3.6Å; F286-C306 WeakPolarHBondContact O-CA 3.35Å; C287-C306 HydrophobicContact CB-CB 4Å; C287-C306 WeakPolarHBondContact CB-SG 3.12Å; C287-C306 WeakPolarHBondContact SG-CB 3.46Å; C287-C306 CovalentContact SG-SG 2.03Å; C287-C306 PolarHBondContact SG-SG 2.85Å
307I97.2Very high96.5Very high0 Ų025 Ų250%013%0.133CC..EExtended strand (participates in β ladder)trans-108.1125.8167.8-54.5-179.1000107.3W14 I16 M133 F201 I203 L285 F286 N309 L312W14-I307 HydrophobicContact CB-CD1 4.22Å; W14-I307 HydrophobicContact CD2-CD1 3.59Å; W14-I307 HydrophobicContact CE3-CD1 3.91Å; W14-I307 HydrophobicContact CG-CD1 3.72Å; W14-I307 HydrophobicContact CZ2-CG2 4.42Å; I16-I307 HydrophobicContact CD1-CD1 4.41Å; M133-I307 HydrophobicContact CE-CD1 3.77Å; M133-I307 HydrophobicContact CE-CG1 4.11Å; M133-I307 HydrophobicContact SD-CD1 4.38Å; F201-I307 HydrophobicContact CB-CG2 4.41Å; I203-I307 HydrophobicContact CD1-CB 4.44Å; I203-I307 HydrophobicContact CD1-CG1 3.88Å; I203-I307 HydrophobicContact CD1-CG2 4.35Å; L285-I307 WeakPolarHBondContact CA-O 3.26Å; F286-I307 PolarHBondContact N-O 3.07Å; F286-I307 VanDerWaalsContact N-O 3.07Å; F286-I307 PolarHBondContact O-N 3.23Å; I307-N309 HydrophobicContact CG2-CB 4.22Å; I307-N309 PolarHBondContact O-N 2.82Å; I307-L312 HydrophobicContact CB-CD2 4.05Å; I307-L312 HydrophobicContact CD1-CD2 4.23Å; I307-L312 HydrophobicContact CG2-CD2 4.18Å
308E96.1Very high96.6Very high60 Ų6027.3 Ų27.328%0.2815%0.152SC..EExtended strand (participates in β ladder)trans-80.5102.4171.1-167.6172.215600109.9S202 R204 L283 P284 L285S202-E308 PolarHBondContact O-N 2.85Å; R204-E308 IonicContact CZ-OE2 3.6Å; R204-E308 IonicContact NE-OE2 3.55Å; R204-E308 PolarHBondContact NE-OE2 3.06Å; R204-E308 IonicContact NH2-OE2 2.75Å; R204-E308 PolarHBondContact NH2-OE2 2.61Å; L283-E308 HydrophobicContact CD1-CG 4.36Å; L283-E308 WeakPolarHBondContact CD1-OE2 3.39Å; P284-E308 WeakPolarHBondContact O-CA 3.5Å; L285-E308 HydrophobicContact CD2-CB 3.75Å; L285-E308 HydrophobicContact CD2-CG 3.97Å
309N95Very high96.7Very high10 Ų1026 Ų265%0.05314%0.144CC..  trans-160.2122.1179.1-178.7-71.3000109.6T33 P35 P284 I307 E311 L312 R313T33-N309 PolarHBondContact O-ND2 3.48Å; P35-N309 WeakPolarHBondContact CG-OD1 3.36Å; P284-N309 PolarHBondContact O-N 2.93Å; I307-N309 HydrophobicContact CG2-CB 4.22Å; I307-N309 PolarHBondContact O-N 2.82Å; N309-E311 PolarHBondContact OD1-N 3.31Å; N309-E311 PolarHBondContact OD1-OE2 3.06Å; N309-L312 HydrophobicContact CB-CB 3.87Å; N309-L312 VanDerWaalsContact OD1-CB 3.29Å; N309-L312 WeakPolarHBondContact OD1-CB 3.43Å; N309-L312 PolarHBondContact OD1-N 2.76Å; N309-R313 WeakPolarHBondContact O-CB 3.36Å; N309-R313 PolarHBondContact O-N 3.42Å
310A95.7Very high96.7Very high41 Ų4124.5 Ų24.534%0.33913%0.132SC..Hα-helixtrans-66.7-42.4-172.100000112.8P284 R313 Q314P284-A310 HydrophobicContact CB-CB 4.18Å; P284-A310 HydrophobicContact CG-CB 4Å; A310-R313 PolarHBondContact O-N 2.78Å; A310-Q314 WeakPolarHBondContact O-CB 3.28Å; A310-Q314 PolarHBondContact O-N 2.81Å
311E95.7Very high96.4Very high70 Ų7027.4 Ų27.433%0.32716%0.158SC..Hα-helixtrans-71-41.4-177.7-65.369.2-149.500110.6P35 N309 Q314 L315P35-E311 HydrophobicContact CG-CB 4.24Å; N309-E311 PolarHBondContact OD1-N 3.31Å; N309-E311 PolarHBondContact OD1-OE2 3.06Å; E311-Q314 CarbonylContact O-C 3.58Å; E311-Q314 WeakPolarHBondContact O-CB 3.03Å; E311-Q314 PolarHBondContact O-N 3.25Å; E311-L315 WeakPolarHBondContact O-CB 3.28Å; E311-L315 PolarHBondContact O-N 3.46Å
312L96.6Very high95.6Very high0 Ų030.5 Ų30.50%018%0.176CC..Hα-helixtrans-64.1-45.6174.4-178.460.2000111.2W14 I16 I29 P35 F286 I307 N309 Q314 L315 F316W14-L312 HydrophobicContact CH2-CD1 4.38Å; W14-L312 HydrophobicContact CH2-CD2 3.88Å; W14-L312 HydrophobicContact CZ2-CD2 4.28Å; W14-L312 HydrophobicContact CZ3-CD2 4.29Å; I16-L312 HydrophobicContact CD1-CD1 3.79Å; I16-L312 HydrophobicContact CD1-CD2 3.82Å; I16-L312 HydrophobicContact CD1-CG 4.37Å; I29-L312 HydrophobicContact CD1-CD1 4.01Å; I29-L312 HydrophobicContact CG2-CD1 4.26Å; P35-L312 HydrophobicContact CG-CB 3.86Å; F286-L312 HydrophobicContact CB-CD2 3.89Å; F286-L312 HydrophobicContact CB-CG 3.74Å; F286-L312 HydrophobicContact CD1-CD1 4.41Å; F286-L312 HydrophobicContact CD1-CD2 3.77Å; F286-L312 HydrophobicContact CD1-CG 4.02Å; F286-L312 HydrophobicContact CG-CD2 4.17Å; F286-L312 HydrophobicContact CG-CG 4.03Å; I307-L312 HydrophobicContact CB-CD2 4.05Å; I307-L312 HydrophobicContact CD1-CD2 4.23Å; I307-L312 HydrophobicContact CG2-CD2 4.18Å; N309-L312 HydrophobicContact CB-CB 3.87Å; N309-L312 VanDerWaalsContact OD1-CB 3.29Å; N309-L312 WeakPolarHBondContact OD1-CB 3.43Å; N309-L312 PolarHBondContact OD1-N 2.76Å; L312-Q314 VanDerWaalsContact C-N 3.26Å; L312-Q314 PolarHBondContact O-N 2.87Å; L312-L315 WeakPolarHBondContact O-CB 3.34Å; L312-L315 PolarHBondContact O-N 3.13Å; L312-F316 HydrophobicContact CD1-CD2 4.09Å; L312-F316 HydrophobicContact CD1-CE2 4.02Å; L312-F316 PolarHBondContact O-N 3.13Å; L312-F316 VanDerWaalsContact O-N 3.1Å
313R97Very high94.8Very high31 Ų3131.1 Ų31.112%0.11718%0.181CC..Hα-helixtrans-61-37.9173.5179.6-120.355.4107.3-7.4110.9I277 P284 L285 N309 A310 Q317I277-R313 HydrophobicContact CB-CG 4.08Å; I277-R313 HydrophobicContact CG2-CG 4.3Å; P284-R313 HydrophobicContact CB-CB 4.27Å; P284-R313 HydrophobicContact CB-CG 4.45Å; L285-R313 WeakPolarHBondContact O-CG 3.21Å; N309-R313 WeakPolarHBondContact O-CB 3.36Å; N309-R313 PolarHBondContact O-N 3.42Å; A310-R313 PolarHBondContact O-N 2.78Å; R313-Q317 WeakPolarHBondContact O-CB 3.09Å; R313-Q317 PolarHBondContact O-N 3.12Å
314Q96.4Very high94.3Very high110 Ų11036.1 Ų36.151%0.51421%0.207SC..Hα-helixtrans-67.6-36.6175.2-172.1173.68.400112.9A310 E311 L312 Q317 S318A310-Q314 WeakPolarHBondContact O-CB 3.28Å; A310-Q314 PolarHBondContact O-N 2.81Å; E311-Q314 CarbonylContact O-C 3.58Å; E311-Q314 WeakPolarHBondContact O-CB 3.03Å; E311-Q314 PolarHBondContact O-N 3.25Å; L312-Q314 VanDerWaalsContact C-N 3.26Å; L312-Q314 PolarHBondContact O-N 2.87Å; Q314-Q317 WeakPolarHBondContact O-CB 3.29Å; Q314-Q317 PolarHBondContact O-N 2.64Å; Q314-S318 PolarHBondContact O-N 3.16Å; Q314-S318 PolarHBondContact O-OG 3.5Å; Q314-S318 VanDerWaalsContact O-OG 3.05Å
315L96.6Very high93.8Very high27 Ų2739.4 Ų39.414%0.14122%0.224CC..Hα-helixtrans-61.2-48.1176.1-164.461.5000110.4I29 W37 E311 L312 Q317 S318 V319I29-L315 HydrophobicContact CD1-CD2 3.43Å; I29-L315 VanDerWaalsContact CD1-CD2 3.43Å; I29-L315 HydrophobicContact CG1-CD2 3.83Å; W37-L315 HydrophobicContact CD2-CD2 4.17Å; W37-L315 HydrophobicContact CG-CD2 4.36Å; W37-L315 HydrophobicContact CZ2-CD2 4.16Å; W37-L315 HydrophobicContact CZ2-CG 4.08Å; W37-L315 VanDerWaalsContact NE1-CD1 3.27Å; E311-L315 WeakPolarHBondContact O-CB 3.28Å; E311-L315 PolarHBondContact O-N 3.46Å; L312-L315 WeakPolarHBondContact O-CB 3.34Å; L312-L315 PolarHBondContact O-N 3.13Å; L315-Q317 PolarHBondContact O-N 2.98Å; L315-S318 WeakPolarHBondContact O-CA 3.46Å; L315-S318 VanDerWaalsContact O-CB 3.29Å; L315-S318 WeakPolarHBondContact O-CB 3.26Å; L315-S318 PolarHBondContact O-N 3.37Å; L315-V319 WeakPolarHBondContact O-CG2 3.47Å; L315-V319 PolarHBondContact O-N 2.93Å
316F97.4Very high93.3Very high0 Ų041 Ų410%023%0.231CC..Hα-helixtrans-73-25.4176.4-84.4-91.9000113.9I16 Y18 I29 W37 W275 I277 F286 L312 S318 V319 A320I16-F316 HydrophobicContact CG2-CZ 4.32Å; Y18-F316 HydrophobicContact CD2-CE1 4.19Å; Y18-F316 HydrophobicContact CD2-CZ 4.39Å; Y18-F316 HydrophobicContact CE2-CE1 4.13Å; I29-F316 HydrophobicContact CD1-CE2 3.8Å; I29-F316 HydrophobicContact CD1-CZ 4.45Å; W37-F316 HydrophobicContact CH2-CZ 4.28Å; W275-F316 AromaticContact CD2-CD1 3.93Å; W275-F316 HydrophobicContact CD2-CD1 3.93Å; W275-F316 HydrophobicContact CD2-CE1 4.34Å; W275-F316 HydrophobicContact CE3-CD1 4.03Å; W275-F316 HydrophobicContact CG-CD1 4.46Å; W275-F316 HydrophobicContact CG-CE1 4.45Å; W275-F316 HydrophobicContact CH2-CD1 4.35Å; W275-F316 HydrophobicContact CZ2-CD1 4.24Å; W275-F316 HydrophobicContact CZ3-CB 4.34Å; W275-F316 HydrophobicContact CZ3-CD1 4.25Å; I277-F316 HydrophobicContact CG2-CB 3.67Å; F286-F316 HydrophobicContact CD1-CD2 4.41Å; F286-F316 HydrophobicContact CD1-CE2 4.29Å; F286-F316 HydrophobicContact CD2-CB 3.79Å; F286-F316 AromaticContact CD2-CD1 3.84Å; F286-F316 HydrophobicContact CD2-CD1 3.84Å; F286-F316 AromaticContact CD2-CD2 3.42Å; F286-F316 HydrophobicContact CD2-CD2 3.42Å; F286-F316 VanDerWaalsContact CD2-CD2 3.42Å; F286-F316 HydrophobicContact CD2-CE1 4.26Å; F286-F316 AromaticContact CD2-CE2 3.9Å; F286-F316 HydrophobicContact CD2-CE2 3.9Å; F286-F316 AromaticContact CD2-CG 3.38Å; F286-F316 HydrophobicContact CD2-CG 3.38Å; F286-F316 HydrophobicContact CD2-CZ 4.29Å; F286-F316 HydrophobicContact CE1-CD2 4.4Å; F286-F316 AromaticContact CE1-CE2 3.92Å; F286-F316 HydrophobicContact CE1-CE2 3.92Å; F286-F316 HydrophobicContact CE1-CZ 4.08Å; F286-F316 HydrophobicContact CE2-CB 4.11Å; F286-F316 AromaticContact CE2-CD1 3.25Å; F286-F316 HydrophobicContact CE2-CD1 3.25Å; F286-F316 AromaticContact CE2-CD2 3.43Å; F286-F316 HydrophobicContact CE2-CD2 3.43Å; F286-F316 VanDerWaalsContact CE2-CD2 3.43Å; F286-F316 AromaticContact CE2-CE1 3.32Å; F286-F316 HydrophobicContact CE2-CE1 3.32Å; F286-F316 AromaticContact CE2-CE2 3.51Å; F286-F316 HydrophobicContact CE2-CE2 3.51Å; F286-F316 AromaticContact CE2-CG 3.29Å; F286-F316 HydrophobicContact CE2-CG 3.29Å; F286-F316 AromaticContact CE2-CZ 3.45Å; F286-F316 HydrophobicContact CE2-CZ 3.45Å; F286-F316 VanDerWaalsContact CE2-CZ 3.45Å; F286-F316 AromaticContact CG-CD2 3.93Å; F286-F316 HydrophobicContact CG-CD2 3.93Å; F286-F316 HydrophobicContact CG-CE2 4.26Å; F286-F316 HydrophobicContact CG-CG 4.32Å; F286-F316 HydrophobicContact CZ-CD1 4Å; F286-F316 AromaticContact CZ-CD2 3.92Å; F286-F316 HydrophobicContact CZ-CD2 3.92Å; F286-F316 AromaticContact CZ-CE1 3.57Å; F286-F316 HydrophobicContact CZ-CE1 3.57Å; F286-F316 AromaticContact CZ-CE2 3.49Å; F286-F316 HydrophobicContact CZ-CE2 3.49Å; F286-F316 VanDerWaalsContact CZ-CE2 3.49Å; F286-F316 HydrophobicContact CZ-CG 4.15Å; F286-F316 AromaticContact CZ-CZ 3.3Å; F286-F316 HydrophobicContact CZ-CZ 3.3Å; L312-F316 HydrophobicContact CD1-CD2 4.09Å; L312-F316 HydrophobicContact CD1-CE2 4.02Å; L312-F316 PolarHBondContact O-N 3.13Å; L312-F316 VanDerWaalsContact O-N 3.1Å; F316-S318 PolarHBondContact O-N 2.97Å; F316-V319 HydrophobicContact CD1-CB 4.36Å; F316-V319 HydrophobicContact CD1-CG2 4.31Å; F316-V319 WeakPolarHBondContact O-CB 2.95Å; F316-V319 PolarHBondContact O-N 3.46Å; F316-A320 PolarHBondContact O-N 3.17Å
317Q96.3Very high92.5Very high66 Ų6644.3 Ų44.331%0.30826%0.259SS..Hα-helixtrans-60.9-36.7166.1-175.364.56300111.3I277 R313 Q314 L315 A320 A321I277-Q317 HydrophobicContact CD1-CB 3.91Å; I277-Q317 HydrophobicContact CD1-CG 4.48Å; I277-Q317 VanDerWaalsContact CD1-OE1 3.24Å; R313-Q317 WeakPolarHBondContact O-CB 3.09Å; R313-Q317 PolarHBondContact O-N 3.12Å; Q314-Q317 WeakPolarHBondContact O-CB 3.29Å; Q314-Q317 PolarHBondContact O-N 2.64Å; L315-Q317 PolarHBondContact O-N 2.98Å; Q317-A320 WeakPolarHBondContact O-CB 3.5Å; Q317-A320 PolarHBondContact O-N 3.33Å; Q317-A321 PolarHBondContact O-N 3.23Å
318S96Very high91.9Very high71 Ų7148 Ų4850%0.49728%0.284SS..Hα-helixtrans-71.9-35.6175-52.60000111.7Q314 L315 F316 A320 A321Q314-S318 PolarHBondContact O-N 3.16Å; Q314-S318 PolarHBondContact O-OG 3.5Å; Q314-S318 VanDerWaalsContact O-OG 3.05Å; L315-S318 WeakPolarHBondContact O-CA 3.46Å; L315-S318 VanDerWaalsContact O-CB 3.29Å; L315-S318 WeakPolarHBondContact O-CB 3.26Å; L315-S318 PolarHBondContact O-N 3.37Å; F316-S318 PolarHBondContact O-N 2.97Å; S318-A320 VanDerWaalsContact C-N 3.25Å; S318-A320 PolarHBondContact O-N 3.31Å; S318-A321 VanDerWaalsContact O-CB 3.24Å; S318-A321 WeakPolarHBondContact O-CB 3.06Å; S318-A321 PolarHBondContact O-N 2.94Å; S318-A321 VanDerWaalsContact O-N 3.12Å
319V97Very high91.7Very high1 Ų147.4 Ų47.41%0.00628%0.284CS..Hα-helixtrans-59.8-38.8171.3176.40000111.6W37 V259 K260 V261 W275 L315 F316 A321W37-V319 HydrophobicContact CZ2-CG2 3.76Å; V259-V319 HydrophobicContact CB-CG1 3.79Å; V259-V319 HydrophobicContact CG1-CG1 4.16Å; V259-V319 HydrophobicContact CG2-CG1 4.39Å; K260-V319 PolarHBondContact N-O 2.81Å; K260-V319 VanDerWaalsContact N-O 3.16Å; K260-V319 WeakPolarHBondContact O-CA 3.47Å; V261-V319 HydrophobicContact CG2-CG1 3.98Å; W275-V319 HydrophobicContact CH2-CG1 4.41Å; W275-V319 HydrophobicContact CZ2-CG1 3.91Å; L315-V319 WeakPolarHBondContact O-CG2 3.47Å; L315-V319 PolarHBondContact O-N 2.93Å; F316-V319 HydrophobicContact CD1-CB 4.36Å; F316-V319 HydrophobicContact CD1-CG2 4.31Å; F316-V319 WeakPolarHBondContact O-CB 2.95Å; F316-V319 PolarHBondContact O-N 3.46Å; V319-A321 VanDerWaalsContact C-N 3.3Å; V319-A321 PolarHBondContact O-N 2.64Å
320A93.9Very high91.5Very high4 Ų449.4 Ų49.43%0.03330%0.296CS..G310 helixtrans-73.4-14.6177.100000114.2L254 W275 F316 Q317 S318 T322 S323L254-A320 HydrophobicContact CD1-CB 3.76Å; L254-A320 HydrophobicContact CD2-CB 3.99Å; W275-A320 HydrophobicContact CH2-CB 4.01Å; F316-A320 PolarHBondContact O-N 3.17Å; Q317-A320 WeakPolarHBondContact O-CB 3.5Å; Q317-A320 PolarHBondContact O-N 3.33Å; S318-A320 VanDerWaalsContact C-N 3.25Å; S318-A320 PolarHBondContact O-N 3.31Å; A320-T322 VanDerWaalsContact C-N 3.26Å; A320-T322 PolarHBondContact O-N 2.67Å; A320-S323 WeakPolarHBondContact O-CB 3.43Å; A320-S323 PolarHBondContact O-N 3.38Å
321A88Confident91.2Very high76 Ų7649.8 Ų49.863%0.62829%0.294SS*.G310 helixtrans-63.6-28-166.200000114.2Q317 S318 V319Q317-A321 PolarHBondContact O-N 3.23Å; S318-A321 VanDerWaalsContact O-CB 3.24Å; S318-A321 WeakPolarHBondContact O-CB 3.06Å; S318-A321 PolarHBondContact O-N 2.94Å; S318-A321 VanDerWaalsContact O-N 3.12Å; V319-A321 VanDerWaalsContact C-N 3.3Å; V319-A321 PolarHBondContact O-N 2.64Å
322T81.6Confident91Very high66 Ų6648.6 Ų48.641%0.40529%0.292SS..G310 helixtrans-85.9-8.8176.259.80000113.4K260 A320K260-T322 HydrophobicContact CB-CG2 3.97Å; K260-T322 HydrophobicContact CD-CG2 4.32Å; A320-T322 VanDerWaalsContact C-N 3.26Å; A320-T322 PolarHBondContact O-N 2.67Å
323S80.9Confident90.6Very high13 Ų1351.7 Ų51.79%0.09131%0.31CS..SBendtrans-86.1134.2179.1170.60000110L254 L255 G256 A320L254-S323 WeakPolarHBondContact CB-OG 3.06Å; L255-S323 PolarHBondContact N-OG 3.15Å; G256-S323 PolarHBondContact N-OG 3.2Å; A320-S323 WeakPolarHBondContact O-CB 3.43Å; A320-S323 PolarHBondContact O-N 3.38Å
324N86.5Confident90.2Very high108 Ų10853.1 Ų53.158%0.57832%0.323SS*.EExtended strand (participates in β ladder)trans-63.7145.1165.9-66.9-41.2000110.3L254 L255 G256L254-N324 CarbonylContact C-O 3.58Å; L255-N324 HydrophobicContact CB-CB 4.35Å; L255-N324 PolarHBondContact N-O 3.19Å; G256-N324 PolarHBondContact O-N 3.01Å; G256-N324 PolarHBondContact O-ND2 2.96Å
325L87.8Confident89.8Confident70 Ų7049 Ų4937%0.36631%0.309SS..EExtended strand (participates in β ladder)trans-98.9134.4173.8-168.168000109.1Q252 L254 A327Q252-L325 HydrophobicContact CB-CD1 3.62Å; Q252-L325 HydrophobicContact CB-CD2 4.36Å; Q252-L325 HydrophobicContact CB-CG 4.05Å; Q252-L325 VanDerWaalsContact NE2-CD2 3.33Å; L254-L325 HydrophobicContact CD2-CD1 3.9Å; L325-A327 VanDerWaalsContact C-N 3.29Å; L325-A327 PolarHBondContact O-N 3.09Å
326E88.1Confident89.2Confident36 Ų3650.7 Ų50.717%0.16832%0.322CS..  trans-75.191.4161.6-168.2176.2-118.600107.4K240 S243 N253 L255K240-E326 IonicContact NZ-OE1 3Å; K240-E326 PolarHBondContact NZ-OE1 3.44Å; S243-E326 PolarHBondContact N-OE2 3.36Å; S243-E326 WeakPolarHBondContact OG-CB 3.45Å; S243-E326 PolarHBondContact OG-O 2.85Å; S243-E326 VanDerWaalsContact OG-O 3.06Å; S243-E326 PolarHBondContact OG-OE2 3.39Å; N253-E326 HydrophobicContact CB-CB 4.1Å; N253-E326 PolarHBondContact ND2-OE2 2.96Å; N253-E326 PolarHBondContact O-N 3.32Å; L255-E326 HydrophobicContact CD1-CB 3.71Å; L255-E326 HydrophobicContact CD1-CG 4.27Å; L255-E326 HydrophobicContact CD2-CB 3.89Å; L255-E326 HydrophobicContact CD2-CG 4.49Å; L255-E326 HydrophobicContact CG-CB 3.72Å
327A83.4Confident88.5Confident71 Ų7154.9 Ų54.959%0.58735%0.349SS*.  trans-64.3142.5-178.700000111.1L325L325-A327 VanDerWaalsContact C-N 3.29Å; L325-A327 PolarHBondContact O-N 3.09Å
328C83.2Confident87.8Confident77 Ų7753.9 Ų53.952%0.5235%0.353SS..  trans-780149.6-60.80000107.8C245 K250C245-C328 WeakPolarHBondContact CA-SG 3.19Å; C245-C328 HydrophobicContact CB-CB 3.55Å; C245-C328 WeakPolarHBondContact CB-SG 3.45Å; C245-C328 WeakPolarHBondContact SG-CA 3.21Å; C245-C328 WeakPolarHBondContact SG-CB 3.22Å; C245-C328 CovalentContact SG-SG 2.03Å; C245-C328 PolarHBondContact SG-SG 3.13Å; K250-C328 HydrophobicContact CD-CB 3.71Å

Retrieved 328 of 328 residues in 277 ms (Link to these results)