A0A077Z3U5_TRITR Loading...

Serotonin receptor protein

AlphaFold DB , UniProt , Accession A0A077Z3U5, Species TRITR (Trichuris trichiura, Whipworm), Gene n/a, Length 456 aa.

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(Predicted Aligned Error values between residue pairs)

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Site	Residue	pLDDT	pLDDT confidence	pLDDT₁₀	pLDDT10 confidence	SASA	SASA [Å²]	SASA₁₀	SASA10 [Å²]	RSA	RSA unformatted	RSA₁₀	RSA10 unformatted	Surface	Surface10 (not used)	Disorder (not used)	Disorder	Sec. str.	Secondary structure	Isomer	Phi (φ)	Psi (ψ)	Omega (ω)	Chi 1 (χ₁)	Chi 2 (χ₂)	Chi 3 (χ₃)	Chi 4 (χ₄)	Chi 5 (χ₅)	Tau (τ)	Contacts (colored by PAE)	Contact details
1	M	41	Very low	40.4	Very low	215 Å²	215	123.9 Å²	123.9	100%	1.059	59%	0.591	S	S	*	*				0	-60.1	0	-145.5	-174	-65.4	0	0	111	E3 S4 Y5	M1-E3 VanDerWaalsContact C-N 3.35Å; M1-E3 PolarHBondContact O-N 3.06Å; M1-S4 WeakPolarHBondContact O-CB 3.4Å; M1-S4 PolarHBondContact O-N 2.97Å; M1-Y5 PolarHBondContact O-N 2.79Å
2	L	36.1	Very low	40.6	Very low	140 Å²	140	123.8 Å²	123.8	73%	0.733	59%	0.592	S	S	*	*	H	α-helix	trans	-49.5	-44.2	175.3	-89.2	151.1	0	0	0	114.7	S4 Y5 E6	L2-S4 VanDerWaalsContact C-N 3.28Å; L2-S4 PolarHBondContact O-N 3.28Å; L2-Y5 WeakPolarHBondContact O-CA 3.34Å; L2-Y5 VanDerWaalsContact O-CB 3.32Å; L2-Y5 WeakPolarHBondContact O-CB 3.31Å; L2-Y5 PolarHBondContact O-N 2.94Å; L2-E6 PolarHBondContact O-N 3.49Å
3	E	38.4	Very low	40.7	Very low	152 Å²	152	118.9 Å²	118.9	71%	0.71	59%	0.585	S	S	*	*	H	α-helix	trans	-63.8	-29.9	177.2	-63.5	177.9	136.6	0	0	113.9	M1 Y5 R7	M1-E3 VanDerWaalsContact C-N 3.35Å; M1-E3 PolarHBondContact O-N 3.06Å; E3-Y5 VanDerWaalsContact C-N 3.28Å; E3-R7 VanDerWaalsContact O-CB 3.28Å; E3-R7 WeakPolarHBondContact O-CB 3.24Å; E3-R7 PolarHBondContact O-N 2.92Å
4	S	39.8	Very low	40.7	Very low	58 Å²	58	120.6 Å²	120.6	41%	0.406	59%	0.59	S	S	.	*	H	α-helix	trans	-77.5	-16.9	175	-178	0	0	0	0	112.4	M1 L2 R8	M1-S4 WeakPolarHBondContact O-CB 3.4Å; M1-S4 PolarHBondContact O-N 2.97Å; L2-S4 VanDerWaalsContact C-N 3.28Å; L2-S4 PolarHBondContact O-N 3.28Å; S4-R8 PolarHBondContact O-NE 3.41Å; S4-R8 PolarHBondContact OG-NH2 3.31Å
5	Y	38.8	Very low	40.8	Very low	120 Å²	120	122.1 Å²	122.1	47%	0.471	60%	0.596	S	S	.	*	H	α-helix	trans	-83.5	-49.6	172.2	-178.2	-96.8	0	0	0	110.5	M1 L2 E3 R7 R8 K9	M1-Y5 PolarHBondContact O-N 2.79Å; L2-Y5 WeakPolarHBondContact O-CA 3.34Å; L2-Y5 VanDerWaalsContact O-CB 3.32Å; L2-Y5 WeakPolarHBondContact O-CB 3.31Å; L2-Y5 PolarHBondContact O-N 2.94Å; E3-Y5 VanDerWaalsContact C-N 3.28Å; Y5-R7 PolarHBondContact O-N 2.96Å; Y5-R8 PolarHBondContact O-N 3.35Å; Y5-K9 WeakPolarHBondContact O-CB 3.35Å; Y5-K9 PolarHBondContact O-N 3.24Å
6	E	42.8	Very low	40.5	Very low	101 Å²	101	119.6 Å²	119.6	47%	0.472	59%	0.585	S	S	.	*	H	α-helix	trans	-62.2	-39.6	175.9	-73.7	-61.9	142.4	0	0	112.5	L2 R8 K9 G10	L2-E6 PolarHBondContact O-N 3.49Å; E6-R8 PolarHBondContact O-N 3.35Å; E6-K9 WeakPolarHBondContact O-CB 3.43Å; E6-K9 PolarHBondContact O-N 2.95Å; E6-K9 VanDerWaalsContact O-N 3.16Å; E6-K9 IonicContact OE1-NZ 3.77Å; E6-K9 PolarHBondContact OE1-NZ 3.3Å; E6-K9 IonicContact OE2-NZ 3.97Å; E6-G10 PolarHBondContact O-N 3Å; E6-G10 VanDerWaalsContact O-N 3.08Å
7	R	38.5	Very low	40.6	Very low	178 Å²	178	118.6 Å²	118.6	67%	0.672	59%	0.588	S	S	*	*	H	α-helix	trans	-62.6	-43.1	176.5	-154.1	176.8	-61.2	174.2	0.4	112.1	E3 Y5 K9 G10 D11	E3-R7 VanDerWaalsContact O-CB 3.28Å; E3-R7 WeakPolarHBondContact O-CB 3.24Å; E3-R7 PolarHBondContact O-N 2.92Å; Y5-R7 PolarHBondContact O-N 2.96Å; R7-K9 VanDerWaalsContact C-N 3.31Å; R7-K9 PolarHBondContact O-N 3.35Å; R7-G10 PolarHBondContact O-N 3.29Å; R7-D11 PolarHBondContact O-N 3.17Å; R7-D11 VanDerWaalsContact O-N 3.15Å
8	R	43.5	Very low	40.6	Very low	158 Å²	158	117 Å²	117	60%	0.596	59%	0.585	S	S	*	*	H	α-helix	trans	-63.7	-33.1	173.3	-92.4	-178.7	-86.8	-159.8	-10.5	113.4	S4 Y5 E6 G10 D11 M12	S4-R8 PolarHBondContact O-NE 3.41Å; S4-R8 PolarHBondContact OG-NH2 3.31Å; Y5-R8 PolarHBondContact O-N 3.35Å; E6-R8 PolarHBondContact O-N 3.35Å; R8-G10 VanDerWaalsContact C-N 3.34Å; R8-D11 PolarHBondContact O-N 3.22Å; R8-M12 WeakPolarHBondContact O-CB 3.41Å; R8-M12 WeakPolarHBondContact O-CG 3.42Å; R8-M12 PolarHBondContact O-N 3.08Å
9	K	44.2	Very low	40.6	Very low	114 Å²	114	114.5 Å²	114.5	50%	0.496	59%	0.585	S	S	.	*	H	α-helix	trans	-67.9	-34.6	176.7	-162.5	-174.9	-177.6	-170.5	0	111.8	Y5 E6 R7 A13	Y5-K9 WeakPolarHBondContact O-CB 3.35Å; Y5-K9 PolarHBondContact O-N 3.24Å; E6-K9 WeakPolarHBondContact O-CB 3.43Å; E6-K9 PolarHBondContact O-N 2.95Å; E6-K9 VanDerWaalsContact O-N 3.16Å; E6-K9 IonicContact OE1-NZ 3.77Å; E6-K9 PolarHBondContact OE1-NZ 3.3Å; E6-K9 IonicContact OE2-NZ 3.97Å; R7-K9 VanDerWaalsContact C-N 3.31Å; R7-K9 PolarHBondContact O-N 3.35Å; K9-A13 PolarHBondContact O-N 3.45Å
10	G	39.3	Very low	40.7	Very low	42 Å²	42	113.9 Å²	113.9	43%	0.433	59%	0.587	S	S	.	*	H	α-helix	trans	-64	-54.9	169.6	0	0	0	0	0	112.3	E6 R7 R8 M12 A13 E14	E6-G10 PolarHBondContact O-N 3Å; E6-G10 VanDerWaalsContact O-N 3.08Å; R7-G10 PolarHBondContact O-N 3.29Å; R8-G10 VanDerWaalsContact C-N 3.34Å; G10-M12 VanDerWaalsContact C-N 3.29Å; G10-M12 PolarHBondContact O-N 3.04Å; G10-A13 WeakPolarHBondContact O-CB 3.46Å; G10-A13 PolarHBondContact O-N 2.88Å; G10-E14 PolarHBondContact O-N 2.89Å; G10-E14 VanDerWaalsContact O-N 3.08Å
11	D	42.2	Very low	40.6	Very low	85 Å²	85	111.5 Å²	111.5	46%	0.455	59%	0.59	S	S	.	*	H	α-helix	trans	-58.5	-38.9	-178.4	-59.3	-25.2	0	0	0	112.4	R7 R8 E14 Q15	R7-D11 PolarHBondContact O-N 3.17Å; R7-D11 VanDerWaalsContact O-N 3.15Å; R8-D11 PolarHBondContact O-N 3.22Å; D11-E14 PolarHBondContact O-N 3.1Å; D11-Q15 WeakPolarHBondContact O-CG 3.32Å; D11-Q15 PolarHBondContact O-N 3.43Å; D11-Q15 VanDerWaalsContact O-N 3.09Å
12	M	43.1	Very low	40.4	Very low	123 Å²	123	109.7 Å²	109.7	61%	0.606	58%	0.576	S	S	*	*	H	α-helix	trans	-68.9	-33.9	176	-73.1	-172.2	78.6	0	0	113.2	R8 G10 L16	R8-M12 WeakPolarHBondContact O-CB 3.41Å; R8-M12 WeakPolarHBondContact O-CG 3.42Å; R8-M12 PolarHBondContact O-N 3.08Å; G10-M12 VanDerWaalsContact C-N 3.29Å; G10-M12 PolarHBondContact O-N 3.04Å; M12-L16 WeakPolarHBondContact O-CB 3.34Å; M12-L16 PolarHBondContact O-N 3.24Å
13	A	41.1	Very low	40.1	Very low	60 Å²	60	108.9 Å²	108.9	50%	0.496	58%	0.582	S	S	.	*	H	α-helix	trans	-68.6	-39.9	176	0	0	0	0	0	111.5	K9 G10 V17	K9-A13 PolarHBondContact O-N 3.45Å; G10-A13 WeakPolarHBondContact O-CB 3.46Å; G10-A13 PolarHBondContact O-N 2.88Å; A13-V17 WeakPolarHBondContact O-CG2 3.47Å; A13-V17 PolarHBondContact O-N 3.44Å
14	E	41.3	Very low	39.8	Very low	142 Å²	142	107.7 Å²	107.7	66%	0.664	59%	0.586	S	S	*	*	H	α-helix	trans	-70.5	-43.3	-179.6	-160.3	170.1	-153.8	0	0	112	G10 D11 L16 V17 V18	G10-E14 PolarHBondContact O-N 2.89Å; G10-E14 VanDerWaalsContact O-N 3.08Å; D11-E14 PolarHBondContact O-N 3.1Å; E14-L16 VanDerWaalsContact C-N 3.3Å; E14-L16 PolarHBondContact O-N 3.01Å; E14-V17 PolarHBondContact O-N 3.12Å; E14-V18 PolarHBondContact O-N 3.45Å
15	Q	41.6	Very low	39.5	Very low	144 Å²	144	110.9 Å²	110.9	67%	0.673	60%	0.602	S	S	*	*	H	α-helix	trans	-64	-32.9	176.1	-70.9	-175.4	17.2	0	0	113.1	D11 V18 A19	D11-Q15 WeakPolarHBondContact O-CG 3.32Å; D11-Q15 PolarHBondContact O-N 3.43Å; D11-Q15 VanDerWaalsContact O-N 3.09Å; Q15-V18 PolarHBondContact O-N 2.99Å; Q15-A19 PolarHBondContact O-N 3.46Å; Q15-A19 VanDerWaalsContact O-N 3.09Å
16	L	36.5	Very low	39	Very low	81 Å²	81	112.1 Å²	112.1	42%	0.424	62%	0.617	S	S	.	*	H	α-helix	trans	-70.1	-34.2	178	-130.4	87.9	0	0	0	113	M12 E14 A19 T20	M12-L16 WeakPolarHBondContact O-CB 3.34Å; M12-L16 PolarHBondContact O-N 3.24Å; E14-L16 VanDerWaalsContact C-N 3.3Å; E14-L16 PolarHBondContact O-N 3.01Å; L16-A19 PolarHBondContact O-N 3.15Å; L16-T20 PolarHBondContact O-N 2.87Å; L16-T20 PolarHBondContact O-OG1 3.48Å
17	V	41.5	Very low	38.8	Very low	104 Å²	104	115.4 Å²	115.4	63%	0.63	64%	0.638	S	S	*	*	H	α-helix	trans	-68.3	-40.2	176	171.9	0	0	0	0	110.7	A13 E14 A19 T20 G21	A13-V17 WeakPolarHBondContact O-CG2 3.47Å; A13-V17 PolarHBondContact O-N 3.44Å; E14-V17 PolarHBondContact O-N 3.12Å; V17-A19 VanDerWaalsContact C-N 3.34Å; V17-A19 PolarHBondContact O-N 2.96Å; V17-T20 PolarHBondContact O-N 2.95Å; V17-T20 PolarHBondContact O-OG1 3.44Å; V17-G21 PolarHBondContact O-N 3.17Å
18	V	41.6	Very low	38.6	Very low	89 Å²	89	111.1 Å²	111.1	54%	0.539	64%	0.635	S	S	.	*	H	α-helix	trans	-64.7	-37.2	175.3	176.5	0	0	0	0	111.9	E14 Q15 G21	E14-V18 PolarHBondContact O-N 3.45Å; Q15-V18 PolarHBondContact O-N 2.99Å; V18-G21 PolarHBondContact O-N 3.24Å
19	A	39.6	Very low	38.3	Very low	70 Å²	70	112.3 Å²	112.3	58%	0.579	65%	0.648	S	S	*	*	H	α-helix	trans	-67.6	-35.4	177	0	0	0	0	0	113.2	Q15 L16 V17 G21	Q15-A19 PolarHBondContact O-N 3.46Å; Q15-A19 VanDerWaalsContact O-N 3.09Å; L16-A19 PolarHBondContact O-N 3.15Å; V17-A19 VanDerWaalsContact C-N 3.34Å; V17-A19 PolarHBondContact O-N 2.96Å; A19-G21 VanDerWaalsContact C-N 3.33Å
20	T	43.7	Very low	37.6	Very low	102 Å²	102	114.5 Å²	114.5	63%	0.626	66%	0.661	S	S	*	*	H	α-helix	trans	-78.3	-12.4	177.4	48.3	0	0	0	0	114.6	L16 V17	L16-T20 PolarHBondContact O-N 2.87Å; L16-T20 PolarHBondContact O-OG1 3.48Å; V17-T20 PolarHBondContact O-N 2.95Å; V17-T20 PolarHBondContact O-OG1 3.44Å
21	G	38.2	Very low	37.1	Very low	64 Å²	64	120.4 Å²	120.4	66%	0.66	68%	0.682	S	S	*	*	T	Hydrogen-bonded Turn	trans	-93.1	2.3	-176.5	0	0	0	0	0	116.4	V17 V18 A19	V17-G21 PolarHBondContact O-N 3.17Å; V18-G21 PolarHBondContact O-N 3.24Å; A19-G21 VanDerWaalsContact C-N 3.33Å
22	K	35.9	Very low	36.8	Very low	176 Å²	176	122.2 Å²	122.2	77%	0.765	70%	0.696	S	S	*	*	S	Bend	trans	-128.1	5	-167.5	-87.3	-174.5	175.4	178.8	0	117.9
23	S	31.2	Very low	36.3	Very low	123 Å²	123	121.7 Å²	121.7	86%	0.86	70%	0.7	S	S	*	*			trans	-102.7	88.7	170.3	-72.7	0	0	0	0	111.7
24	T	31.6	Very low	36.1	Very low	127 Å²	127	127 Å²	127	78%	0.779	72%	0.718	S	S	*	*			trans	-104.2	151.9	158.3	49.1	0	0	0	0	109.7
25	V	32.4	Very low	35.9	Very low	125 Å²	125	124.6 Å²	124.6	76%	0.758	72%	0.717	S	S	*	*	S	Bend	trans	80.9	129.1	167.8	-170.8	0	0	0	0	117.1
26	N	29.6	Very low	35.3	Very low	146 Å²	146	125.3 Å²	125.3	78%	0.781	73%	0.726	S	S	*	*			trans	66.7	104.4	171.3	-63.2	-11	0	0	0	118.6
27	D	38.9	Very low	35.4	Very low	170 Å²	170	129.1 Å²	129.1	91%	0.909	75%	0.745	S	S	*	*				-155.1	153.7	115.2	-113.7	-26.7	0	0	0	113.1
28	S	32.6	Very low	35	Very low	88 Å²	88	129 Å²	129	62%	0.615	75%	0.748	S	S	*	*			trans	-97.2	166.2	-170.4	-56.1	0	0	0	0	112.7
29	H	37.9	Very low	34.8	Very low	184 Å²	184	131.4 Å²	131.4	85%	0.852	76%	0.764	S	S	*	*			trans	72.1	137.7	176.7	-42.5	-84.3	0	0	0	114.6
30	M	30.2	Very low	34.7	Very low	159 Å²	159	131.3 Å²	131.3	78%	0.783	77%	0.769	S	S	*	*			cis	-149	112	7.3	-171.7	-171.4	-58	0	0	109.8	V32	M30-V32 HydrophobicContact CG-CG2 4.24Å; M30-V32 HydrophobicContact SD-CG2 4.1Å
31	L	28.7	Very low	34.6	Very low	166 Å²	166	133.1 Å²	133.1	87%	0.869	78%	0.779	S	S	*	*			trans	-81.3	119.2	165.1	-84.9	162.5	0	0	0	108.8
32	V	34.6	Very low	34.8	Very low	123 Å²	123	138.9 Å²	138.9	75%	0.745	79%	0.789	S	S	*	*			trans	-100	94.1	164.6	179.9	0	0	0	0	108.2	M30	M30-V32 HydrophobicContact CG-CG2 4.24Å; M30-V32 HydrophobicContact SD-CG2 4.1Å
33	T	34.3	Very low	35.4	Very low	112 Å²	112	134.8 Å²	134.8	69%	0.687	78%	0.779	S	S	*	*			trans	-68.4	137.3	174.4	-49.7	0	0	0	0	110.3	S35	T33-S35 PolarHBondContact O-N 3Å
34	I	36.6	Very low	36.5	Very low	172 Å²	172	130.9 Å²	130.9	88%	0.882	76%	0.757	S	S	*	*			trans	-72.5	115.8	174.4	-62.5	169.9	0	0	0	109.2
35	S	35.9	Very low	38.1	Very low	92 Å²	92	130.5 Å²	130.5	64%	0.643	76%	0.757	S	S	*	*			trans	-157.1	114.5	165.6	53.2	0	0	0	0	113.1	T33	T33-S35 PolarHBondContact O-N 3Å
36	N	30.5	Very low	39.6	Very low	159 Å²	159	131.3 Å²	131.3	85%	0.85	76%	0.756	S	S	*	*			trans	33.8	91.8	154.2	-61.9	-8.4	0	0	0	119.7
37	I	37.8	Very low	41.7	Very low	161 Å²	161	125.8 Å²	125.8	83%	0.826	73%	0.734	S	S	*	*			trans	-134.5	114.3	145.7	-61.6	-176.3	0	0	0	110.1
38	S	33.8	Very low	43.3	Very low	100 Å²	100	120.1 Å²	120.1	70%	0.699	71%	0.71	S	S	*	*			trans	-71.6	147.4	164.5	-36.7	0	0	0	0	110
39	T	37.5	Very low	45.5	Very low	141 Å²	141	121.3 Å²	121.3	87%	0.865	71%	0.709	S	S	*	*	S	Bend	trans	78.3	127.3	170.1	75.8	0	0	0	0	118.1
40	G	36	Very low	47.7	Very low	67 Å²	67	115.6 Å²	115.6	69%	0.691	69%	0.69	S	S	*	*			trans	84.7	76.2	157.8	0	0	0	0	0	118.5	H42	G40-H42 PolarHBondContact O-N 2.86Å
41	V	42.3	Very low	50.5	Low	140 Å²	140	112.5 Å²	112.5	85%	0.848	68%	0.676	S	S	*	*			trans	-73	87.5	169	-176.4	0	0	0	0	110.8	V43	V41-V43 HydrophobicContact CG1-CG2 4.32Å; V41-V43 PolarHBondContact O-N 2.97Å
42	H	42	Very low	53.4	Low	185 Å²	185	111.3 Å²	111.3	86%	0.856	66%	0.664	S	S	*	*			trans	-72	105.3	162.4	-96.1	-86	0	0	0	109.6	G40 G44	G40-H42 PolarHBondContact O-N 2.86Å; H42-G44 PolarHBondContact O-N 3.09Å
43	V	49.6	Very low	56	Low	91 Å²	91	107.8 Å²	107.8	55%	0.552	64%	0.643	S	S	*	*			trans	-70	111.1	171.4	-173	0	0	0	0	108.4	V41	V41-V43 HydrophobicContact CG1-CG2 4.32Å; V41-V43 PolarHBondContact O-N 2.97Å
44	G	54	Low	58.8	Low	40 Å²	40	105.7 Å²	105.7	41%	0.412	63%	0.627	S	S	.	*			trans	-63.3	163.9	179.1	0	0	0	0	0	113.2	H42 I46 G47 A48	H42-G44 PolarHBondContact O-N 3.09Å; G44-I46 PolarHBondContact O-N 3.19Å; G44-I46 VanDerWaalsContact O-N 3.09Å; G44-G47 WeakPolarHBondContact O-CA 3.29Å; G44-G47 PolarHBondContact O-N 2.95Å; G44-A48 PolarHBondContact O-N 2.81Å
45	P	64.1	Low	61.6	Low	120 Å²	120	102.4 Å²	102.4	78%	0.779	61%	0.61	S	S	*	*	H	α-helix	trans	-54.5	-35.4	-173.3	-27.8	35.2	0	0	0	114.7	A48 L49	P45-A48 PolarHBondContact O-N 2.99Å; P45-L49 PolarHBondContact O-N 3.26Å
46	I	65.4	Low	64.4	Low	141 Å²	141	102.4 Å²	102.4	72%	0.723	60%	0.599	S	S	*	*	H	α-helix	trans	-65.7	-43.6	176.5	-61.5	169	0	0	0	110.7	G44 A48 L49 S50	G44-I46 PolarHBondContact O-N 3.19Å; G44-I46 VanDerWaalsContact O-N 3.09Å; I46-A48 VanDerWaalsContact C-N 3.35Å; I46-L49 PolarHBondContact O-N 3.33Å; I46-S50 PolarHBondContact O-N 2.83Å; I46-S50 PolarHBondContact O-OG 3Å
47	G	72.2	Confident	67.4	Low	31 Å²	31	95.4 Å²	95.4	32%	0.32	56%	0.561	S	S	.	*	H	α-helix	trans	-66.2	-36.3	176.1	0	0	0	0	0	112.7	G44 S50 L51	G44-G47 WeakPolarHBondContact O-CA 3.29Å; G44-G47 PolarHBondContact O-N 2.95Å; G47-S50 PolarHBondContact O-N 2.92Å; G47-L51 WeakPolarHBondContact O-CB 3.33Å; G47-L51 PolarHBondContact O-N 3.18Å
48	A	74.1	Confident	70.2	Confident	50 Å²	50	91 Å²	91	41%	0.413	54%	0.541	S	S	.	.	H	α-helix	trans	-65.7	-40.7	174.5	0	0	0	0	0	112.2	G44 P45 I46 L51 F52	G44-A48 PolarHBondContact O-N 2.81Å; P45-A48 PolarHBondContact O-N 2.99Å; I46-A48 VanDerWaalsContact C-N 3.35Å; A48-L51 PolarHBondContact O-N 2.99Å; A48-F52 WeakPolarHBondContact O-CB 3.38Å; A48-F52 PolarHBondContact O-N 3.29Å
49	L	78.7	Confident	73.2	Confident	114 Å²	114	92.5 Å²	92.5	60%	0.597	54%	0.536	S	S	*	.	H	α-helix	trans	-63.8	-47.7	174.2	-179.2	62	0	0	0	111.5	P45 I46 L51 F52 V53	P45-L49 PolarHBondContact O-N 3.26Å; I46-L49 PolarHBondContact O-N 3.33Å; L49-L51 VanDerWaalsContact C-N 3.33Å; L49-L51 PolarHBondContact O-N 3.46Å; L49-F52 PolarHBondContact O-N 2.82Å; L49-V53 WeakPolarHBondContact O-CG2 3.47Å; L49-V53 PolarHBondContact O-N 3.1Å
50	S	82.5	Confident	76	Confident	64 Å²	64	86.1 Å²	86.1	45%	0.448	50%	0.496	S	S	.	.	H	α-helix	trans	-60.3	-41.9	176.8	-61.7	0	0	0	0	112.2	I46 G47 V53 I54	I46-S50 PolarHBondContact O-N 2.83Å; I46-S50 PolarHBondContact O-OG 3Å; G47-S50 PolarHBondContact O-N 2.92Å; S50-V53 PolarHBondContact O-N 2.77Å; S50-I54 WeakPolarHBondContact O-CD1 3.28Å; S50-I54 VanDerWaalsContact O-CG1 3.25Å; S50-I54 WeakPolarHBondContact O-CG1 3.1Å; S50-I54 PolarHBondContact O-N 3.39Å
51	L	89	Confident	78.9	Confident	94 Å²	94	84.4 Å²	84.4	49%	0.492	47%	0.471	S	S	.	.	H	α-helix	trans	-62.3	-43.2	175.1	-180	61.7	0	0	0	111.8	G47 A48 L49 V53 I54 L55	G47-L51 WeakPolarHBondContact O-CB 3.33Å; G47-L51 PolarHBondContact O-N 3.18Å; A48-L51 PolarHBondContact O-N 2.99Å; L49-L51 VanDerWaalsContact C-N 3.33Å; L49-L51 PolarHBondContact O-N 3.46Å; L51-V53 PolarHBondContact O-N 2.91Å; L51-I54 PolarHBondContact O-N 2.87Å; L51-L55 HydrophobicContact CD1-CD1 4.16Å; L51-L55 HydrophobicContact CD1-CG 4.18Å; L51-L55 HydrophobicContact CG-CD1 4Å; L51-L55 HydrophobicContact CG-CG 4.44Å; L51-L55 WeakPolarHBondContact O-CB 3.4Å; L51-L55 VanDerWaalsContact O-CG 3.27Å; L51-L55 WeakPolarHBondContact O-CG 3.15Å; L51-L55 PolarHBondContact O-N 3.48Å
52	F	90.8	Very high	81.6	Confident	140 Å²	140	83 Å²	83	61%	0.614	46%	0.458	S	S	*	.	H	α-helix	trans	-60.9	-43.9	176.1	177.9	-94.9	0	0	0	112.1	A48 L49 L55 F56	A48-F52 WeakPolarHBondContact O-CB 3.38Å; A48-F52 PolarHBondContact O-N 3.29Å; L49-F52 PolarHBondContact O-N 2.82Å; F52-L55 PolarHBondContact O-N 2.73Å; F52-F56 VanDerWaalsContact O-CB 3.3Å; F52-F56 WeakPolarHBondContact O-CB 3.36Å; F52-F56 PolarHBondContact O-N 2.89Å
53	V	89.4	Confident	84.2	Confident	49 Å²	49	76.5 Å²	76.5	30%	0.297	43%	0.431	S	S	.	.	H	α-helix	trans	-62.5	-45.3	176.6	171.3	0	0	0	0	111.4	L49 S50 L51 F56 F57	L49-V53 WeakPolarHBondContact O-CG2 3.47Å; L49-V53 PolarHBondContact O-N 3.1Å; S50-V53 PolarHBondContact O-N 2.77Å; L51-V53 PolarHBondContact O-N 2.91Å; V53-F56 WeakPolarHBondContact O-CB 3.17Å; V53-F56 PolarHBondContact O-N 2.8Å; V53-F57 HydrophobicContact CG1-CD2 4.01Å; V53-F57 HydrophobicContact CG1-CE1 4.06Å; V53-F57 HydrophobicContact CG1-CE2 3.43Å; V53-F57 VanDerWaalsContact CG1-CE2 3.43Å; V53-F57 HydrophobicContact CG1-CZ 3.46Å; V53-F57 VanDerWaalsContact CG1-CZ 3.46Å; V53-F57 WeakPolarHBondContact O-CG 3.24Å; V53-F57 PolarHBondContact O-N 2.97Å
54	I	93	Very high	86.5	Confident	68 Å²	68	72.2 Å²	72.2	35%	0.349	41%	0.405	S	S	.	.	H	α-helix	trans	-60.9	-47.4	176.5	-68.4	163.5	0	0	0	110.9	S50 L51 F56 F57 V58 V112	S50-I54 WeakPolarHBondContact O-CD1 3.28Å; S50-I54 VanDerWaalsContact O-CG1 3.25Å; S50-I54 WeakPolarHBondContact O-CG1 3.1Å; S50-I54 PolarHBondContact O-N 3.39Å; L51-I54 PolarHBondContact O-N 2.87Å; I54-F56 VanDerWaalsContact C-N 3.3Å; I54-F56 PolarHBondContact O-N 2.81Å; I54-F57 PolarHBondContact O-N 3.36Å; I54-V58 HydrophobicContact CG2-CG2 4.47Å; I54-V58 WeakPolarHBondContact O-CG2 3.22Å; I54-V58 PolarHBondContact O-N 3.17Å; I54-V112 HydrophobicContact CD1-CG1 4.06Å; I54-V112 HydrophobicContact CG1-CG1 4.11Å; I54-V112 HydrophobicContact CG1-CG2 3.73Å
55	L	94.5	Very high	88.6	Confident	103 Å²	103	72 Å²	72	54%	0.539	40%	0.396	S	S	.	.	H	α-helix	trans	-62.8	-36.6	177.8	-71.2	172.8	0	0	0	112.2	L51 F52 F59	L51-L55 HydrophobicContact CD1-CD1 4.16Å; L51-L55 HydrophobicContact CD1-CG 4.18Å; L51-L55 HydrophobicContact CG-CD1 4Å; L51-L55 HydrophobicContact CG-CG 4.44Å; L51-L55 WeakPolarHBondContact O-CB 3.4Å; L51-L55 VanDerWaalsContact O-CG 3.27Å; L51-L55 WeakPolarHBondContact O-CG 3.15Å; L51-L55 PolarHBondContact O-N 3.48Å; F52-L55 PolarHBondContact O-N 2.73Å; L55-F59 VanDerWaalsContact O-CB 3.28Å; L55-F59 WeakPolarHBondContact O-CB 3.23Å; L55-F59 PolarHBondContact O-N 3.38Å
56	F	94.1	Very high	90.2	Very high	92 Å²	92	68.9 Å²	68.9	40%	0.404	38%	0.38	S	S	.	.	H	α-helix	trans	-65.1	-45.8	174.9	175.1	-105.6	0	0	0	112.1	F52 V53 I54 F59 I60	F52-F56 VanDerWaalsContact O-CB 3.3Å; F52-F56 WeakPolarHBondContact O-CB 3.36Å; F52-F56 PolarHBondContact O-N 2.89Å; V53-F56 WeakPolarHBondContact O-CB 3.17Å; V53-F56 PolarHBondContact O-N 2.8Å; I54-F56 VanDerWaalsContact C-N 3.3Å; I54-F56 PolarHBondContact O-N 2.81Å; F56-F59 PolarHBondContact O-N 2.88Å; F56-I60 HydrophobicContact CD1-CD1 3.95Å; F56-I60 HydrophobicContact CD2-CD1 4.44Å; F56-I60 HydrophobicContact CE1-CD1 3.44Å; F56-I60 VanDerWaalsContact CE1-CD1 3.44Å; F56-I60 HydrophobicContact CE2-CD1 3.98Å; F56-I60 HydrophobicContact CG-CD1 4.43Å; F56-I60 HydrophobicContact CZ-CD1 3.47Å; F56-I60 VanDerWaalsContact CZ-CD1 3.47Å; F56-I60 HydrophobicContact CZ-CG1 4.47Å; F56-I60 WeakPolarHBondContact O-CG1 3.44Å; F56-I60 PolarHBondContact O-N 3.37Å
57	F	94.9	Very high	91.7	Very high	12 Å²	12	62.7 Å²	62.7	5%	0.053	35%	0.351	C	S	.	.	H	α-helix	trans	-63.1	-45.5	175.3	-64.1	-18.9	0	0	0	111.9	V53 I54 F59 I60 I61 A108 D111 V112 W420	V53-F57 HydrophobicContact CG1-CD2 4.01Å; V53-F57 HydrophobicContact CG1-CE1 4.06Å; V53-F57 HydrophobicContact CG1-CE2 3.43Å; V53-F57 VanDerWaalsContact CG1-CE2 3.43Å; V53-F57 HydrophobicContact CG1-CZ 3.46Å; V53-F57 VanDerWaalsContact CG1-CZ 3.46Å; V53-F57 WeakPolarHBondContact O-CG 3.24Å; V53-F57 PolarHBondContact O-N 2.97Å; I54-F57 PolarHBondContact O-N 3.36Å; F57-F59 VanDerWaalsContact C-N 3.3Å; F57-F59 PolarHBondContact O-N 3.35Å; F57-I60 PolarHBondContact O-N 2.95Å; F57-I61 VanDerWaalsContact O-CG1 3.32Å; F57-I61 WeakPolarHBondContact O-CG1 3.38Å; F57-I61 PolarHBondContact O-N 2.94Å; F57-A108 HydrophobicContact CB-CB 4.03Å; F57-A108 HydrophobicContact CD2-CB 3.85Å; F57-A108 HydrophobicContact CG-CB 4.21Å; F57-D111 HydrophobicContact CE2-CB 3.84Å; F57-D111 HydrophobicContact CZ-CB 4.04Å; F57-V112 HydrophobicContact CD2-CG2 3.98Å; F57-V112 HydrophobicContact CE2-CG2 4.02Å; F57-W420 HydrophobicContact CB-CH2 3.94Å; F57-W420 HydrophobicContact CB-CZ2 4.43Å; F57-W420 HydrophobicContact CB-CZ3 4.42Å; F57-W420 AromaticContact CD1-CD2 3.84Å; F57-W420 HydrophobicContact CD1-CD2 3.84Å; F57-W420 AromaticContact CD1-CE2 3.6Å; F57-W420 AromaticContact CD1-CE3 3.89Å; F57-W420 HydrophobicContact CD1-CE3 3.89Å; F57-W420 AromaticContact CD1-CH2 3.52Å; F57-W420 HydrophobicContact CD1-CH2 3.52Å; F57-W420 AromaticContact CD1-CZ2 3.45Å; F57-W420 HydrophobicContact CD1-CZ2 3.45Å; F57-W420 VanDerWaalsContact CD1-CZ2 3.45Å; F57-W420 AromaticContact CD1-CZ3 3.73Å; F57-W420 HydrophobicContact CD1-CZ3 3.73Å; F57-W420 HydrophobicContact CD2-CH2 4.27Å; F57-W420 AromaticContact CD2-CZ2 3.91Å; F57-W420 HydrophobicContact CD2-CZ2 3.91Å; F57-W420 AromaticContact CE1-CD1 3.9Å; F57-W420 AromaticContact CE1-CD2 3.54Å; F57-W420 HydrophobicContact CE1-CD2 3.54Å; F57-W420 AromaticContact CE1-CE2 3.18Å; F57-W420 HydrophobicContact CE1-CE3 4.07Å; F57-W420 HydrophobicContact CE1-CG 4.02Å; F57-W420 HydrophobicContact CE1-CH2 4.03Å; F57-W420 AromaticContact CE1-CZ2 3.48Å; F57-W420 HydrophobicContact CE1-CZ2 3.48Å; F57-W420 VanDerWaalsContact CE1-CZ2 3.48Å; F57-W420 HydrophobicContact CE1-CZ3 4.29Å; F57-W420 AromaticContact CE1-NE1 3.42Å; F57-W420 AromaticContact CE2-CZ2 3.91Å; F57-W420 HydrophobicContact CE2-CZ2 3.91Å; F57-W420 AromaticContact CG-CH2 3.66Å; F57-W420 HydrophobicContact CG-CH2 3.66Å; F57-W420 AromaticContact CG-CZ2 3.68Å; F57-W420 HydrophobicContact CG-CZ2 3.68Å; F57-W420 HydrophobicContact CG-CZ3 4.24Å; F57-W420 HydrophobicContact CZ-CD2 4.3Å; F57-W420 AromaticContact CZ-CE2 3.52Å; F57-W420 AromaticContact CZ-CZ2 3.7Å; F57-W420 HydrophobicContact CZ-CZ2 3.7Å; F57-W420 AromaticContact CZ-NE1 3.41Å
58	V	96.3	Very high	92.9	Very high	68 Å²	68	61.2 Å²	61.2	41%	0.412	34%	0.336	S	S	.	.	H	α-helix	trans	-59.5	-41.4	175.1	170.6	0	0	0	0	111.1	I54 I61 L62	I54-V58 HydrophobicContact CG2-CG2 4.47Å; I54-V58 WeakPolarHBondContact O-CG2 3.22Å; I54-V58 PolarHBondContact O-N 3.17Å; V58-I61 PolarHBondContact O-N 3.17Å; V58-L62 HydrophobicContact CG1-CD1 3.76Å; V58-L62 HydrophobicContact CG1-CG 4.25Å; V58-L62 WeakPolarHBondContact O-CB 3.45Å; V58-L62 VanDerWaalsContact O-CG 3.27Å; V58-L62 WeakPolarHBondContact O-CG 3.45Å; V58-L62 PolarHBondContact O-N 3.48Å
59	F	96.4	Very high	94.1	Very high	133 Å²	133	60.8 Å²	60.8	58%	0.583	33%	0.333	S	S	*	.	H	α-helix	trans	-62.9	-43.1	175.5	176.8	-95.7	0	0	0	112.6	L55 F56 F57 T63	L55-F59 VanDerWaalsContact O-CB 3.28Å; L55-F59 WeakPolarHBondContact O-CB 3.23Å; L55-F59 PolarHBondContact O-N 3.38Å; F56-F59 PolarHBondContact O-N 2.88Å; F57-F59 VanDerWaalsContact C-N 3.3Å; F57-F59 PolarHBondContact O-N 3.35Å; F59-T63 HydrophobicContact CD1-CG2 4.43Å; F59-T63 HydrophobicContact CD2-CG2 4.17Å; F59-T63 HydrophobicContact CE1-CG2 4.07Å; F59-T63 HydrophobicContact CE2-CG2 3.79Å; F59-T63 HydrophobicContact CG-CG2 4.48Å; F59-T63 HydrophobicContact CZ-CG2 3.73Å; F59-T63 WeakPolarHBondContact O-CB 3.5Å; F59-T63 WeakPolarHBondContact O-CG2 3.44Å; F59-T63 PolarHBondContact O-N 2.84Å; F59-T63 PolarHBondContact O-OG1 3.38Å
60	I	96.4	Very high	94.9	Very high	6 Å²	6	57.6 Å²	57.6	3%	0.031	32%	0.316	C	S	.	.	H	α-helix	trans	-62.1	-47.2	175.2	-71.1	168.9	0	0	0	110.9	F56 F57 T63 T64 W420 V424	F56-I60 HydrophobicContact CD1-CD1 3.95Å; F56-I60 HydrophobicContact CD2-CD1 4.44Å; F56-I60 HydrophobicContact CE1-CD1 3.44Å; F56-I60 VanDerWaalsContact CE1-CD1 3.44Å; F56-I60 HydrophobicContact CE2-CD1 3.98Å; F56-I60 HydrophobicContact CG-CD1 4.43Å; F56-I60 HydrophobicContact CZ-CD1 3.47Å; F56-I60 VanDerWaalsContact CZ-CD1 3.47Å; F56-I60 HydrophobicContact CZ-CG1 4.47Å; F56-I60 WeakPolarHBondContact O-CG1 3.44Å; F56-I60 PolarHBondContact O-N 3.37Å; F57-I60 PolarHBondContact O-N 2.95Å; I60-T63 PolarHBondContact O-N 2.96Å; I60-T63 PolarHBondContact O-OG1 2.82Å; I60-T64 VanDerWaalsContact O-CB 3.28Å; I60-T64 WeakPolarHBondContact O-CB 3.37Å; I60-T64 PolarHBondContact O-N 2.61Å; I60-T64 PolarHBondContact O-OG1 3.4Å; I60-W420 HydrophobicContact CB-CZ3 4.43Å; I60-W420 HydrophobicContact CD1-CE3 3.88Å; I60-W420 HydrophobicContact CD1-CZ3 4.2Å; I60-W420 HydrophobicContact CG2-CZ3 4.16Å; I60-V424 HydrophobicContact CD1-CG2 3.59Å; I60-V424 HydrophobicContact CG1-CG2 4.18Å
61	I	97.8	Very high	95.7	Very high	32 Å²	32	54.6 Å²	54.6	16%	0.164	30%	0.295	C	S	.	.	H	α-helix	trans	-59	-53.2	179.4	-69.6	162.3	0	0	0	110.1	F57 V58 T63 T64 V65 P105 A108	F57-I61 VanDerWaalsContact O-CG1 3.32Å; F57-I61 WeakPolarHBondContact O-CG1 3.38Å; F57-I61 PolarHBondContact O-N 2.94Å; V58-I61 PolarHBondContact O-N 3.17Å; I61-T63 PolarHBondContact O-N 3.1Å; I61-T64 PolarHBondContact O-N 2.8Å; I61-V65 WeakPolarHBondContact O-CG2 3.48Å; I61-V65 PolarHBondContact O-N 2.76Å; I61-P105 HydrophobicContact CD1-CG 4.32Å; I61-A108 HydrophobicContact CD1-CB 4.29Å
62	L	97.7	Very high	96.1	Very high	110 Å²	110	51.7 Å²	51.7	58%	0.576	28%	0.28	S	S	*	.	H	α-helix	trans	-62.7	-41.2	-178.5	-70.1	175.5	0	0	0	112.7	V58 A66	V58-L62 HydrophobicContact CG1-CD1 3.76Å; V58-L62 HydrophobicContact CG1-CG 4.25Å; V58-L62 WeakPolarHBondContact O-CB 3.45Å; V58-L62 VanDerWaalsContact O-CG 3.27Å; V58-L62 WeakPolarHBondContact O-CG 3.45Å; V58-L62 PolarHBondContact O-N 3.48Å; L62-A66 WeakPolarHBondContact O-CB 3.2Å; L62-A66 PolarHBondContact O-N 3.47Å
63	T	96.7	Very high	96.4	Very high	49 Å²	49	46.9 Å²	46.9	30%	0.301	27%	0.265	S	S	.	.	H	α-helix	trans	-71.3	-33.6	178.2	52.4	0	0	0	0	112.8	F59 I60 I61 G67	F59-T63 HydrophobicContact CD1-CG2 4.43Å; F59-T63 HydrophobicContact CD2-CG2 4.17Å; F59-T63 HydrophobicContact CE1-CG2 4.07Å; F59-T63 HydrophobicContact CE2-CG2 3.79Å; F59-T63 HydrophobicContact CG-CG2 4.48Å; F59-T63 HydrophobicContact CZ-CG2 3.73Å; F59-T63 WeakPolarHBondContact O-CB 3.5Å; F59-T63 WeakPolarHBondContact O-CG2 3.44Å; F59-T63 PolarHBondContact O-N 2.84Å; F59-T63 PolarHBondContact O-OG1 3.38Å; I60-T63 PolarHBondContact O-N 2.96Å; I60-T63 PolarHBondContact O-OG1 2.82Å; I61-T63 PolarHBondContact O-N 3.1Å; T63-G67 WeakPolarHBondContact O-CA 3.44Å; T63-G67 PolarHBondContact O-N 3.46Å
64	T	98	Very high	96.7	Very high	0 Å²	0	44.5 Å²	44.5	0%	0	25%	0.251	C	S	.	.	H	α-helix	trans	-64.9	-54.3	173.9	-57.6	0	0	0	0	110.9	I60 I61 N68 D96	I60-T64 VanDerWaalsContact O-CB 3.28Å; I60-T64 WeakPolarHBondContact O-CB 3.37Å; I60-T64 PolarHBondContact O-N 2.61Å; I60-T64 PolarHBondContact O-OG1 3.4Å; I61-T64 PolarHBondContact O-N 2.8Å; T64-N68 WeakPolarHBondContact O-CB 3.46Å; T64-N68 PolarHBondContact O-N 3.27Å; T64-N68 PolarHBondContact O-ND2 3.28Å; T64-D96 WeakPolarHBondContact CG2-O 3.29Å
65	V	98.4	Very high	96.9	Very high	35 Å²	35	41.3 Å²	41.3	21%	0.212	24%	0.235	C	C	.	.	H	α-helix	trans	-63.5	-55.4	-179.1	172.1	0	0	0	0	110.9	I61 G67 N68 A69 E97 L101	I61-V65 WeakPolarHBondContact O-CG2 3.48Å; I61-V65 PolarHBondContact O-N 2.76Å; V65-G67 VanDerWaalsContact C-N 3.29Å; V65-G67 PolarHBondContact O-N 3.19Å; V65-N68 PolarHBondContact O-N 3.48Å; V65-A69 WeakPolarHBondContact O-CB 3.45Å; V65-A69 PolarHBondContact O-N 2.86Å; V65-E97 VanDerWaalsContact O-OE2 3.12Å; V65-L101 HydrophobicContact CG1-CD2 4.03Å; V65-L101 HydrophobicContact CG2-CD2 3.77Å; V65-L101 HydrophobicContact CG2-CG 4.11Å
66	A	97.4	Very high	96.9	Very high	55 Å²	55	41.2 Å²	41.2	46%	0.455	23%	0.234	S	C	.	.	H	α-helix	trans	-63.8	-36.2	-178.7	0	0	0	0	0	112.3	L62 L70	L62-A66 WeakPolarHBondContact O-CB 3.2Å; L62-A66 PolarHBondContact O-N 3.47Å; A66-L70 WeakPolarHBondContact O-CB 3.46Å; A66-L70 WeakPolarHBondContact O-CD1 3.42Å; A66-L70 WeakPolarHBondContact O-CG 3.47Å; A66-L70 PolarHBondContact O-N 3.31Å; A66-L70 VanDerWaalsContact O-N 3.12Å
67	G	97.5	Very high	96.9	Very high	11 Å²	11	40.2 Å²	40.2	11%	0.113	24%	0.239	C	C	.	.	H	α-helix	trans	-68	-46	179.5	0	0	0	0	0	113.1	T63 V65 L70 V71 P430	T63-G67 WeakPolarHBondContact O-CA 3.44Å; T63-G67 PolarHBondContact O-N 3.46Å; V65-G67 VanDerWaalsContact C-N 3.29Å; V65-G67 PolarHBondContact O-N 3.19Å; G67-L70 WeakPolarHBondContact O-CB 3.45Å; G67-L70 PolarHBondContact O-N 3.46Å; G67-V71 WeakPolarHBondContact O-CG2 3.25Å; G67-V71 PolarHBondContact O-N 2.78Å; G67-V71 VanDerWaalsContact O-N 3.1Å; G67-P430 WeakPolarHBondContact O-CG 3.36Å
68	N	98.2	Very high	96.9	Very high	0 Å²	0	41.1 Å²	41.1	0%	0	24%	0.243	C	C	.	.	H	α-helix	trans	-78.7	-36.3	-177.5	-70.9	-65.2	0	0	0	112.3	T64 V65 L70 V71 I72 A93 D96 E97 S426 P430	T64-N68 WeakPolarHBondContact O-CB 3.46Å; T64-N68 PolarHBondContact O-N 3.27Å; T64-N68 PolarHBondContact O-ND2 3.28Å; V65-N68 PolarHBondContact O-N 3.48Å; N68-L70 VanDerWaalsContact C-N 3.26Å; N68-L70 PolarHBondContact O-N 2.83Å; N68-V71 WeakPolarHBondContact O-CB 3.4Å; N68-V71 PolarHBondContact O-N 2.81Å; N68-I72 WeakPolarHBondContact O-CG1 3.29Å; N68-I72 PolarHBondContact O-N 3.17Å; N68-A93 HydrophobicContact CB-CB 4.23Å; N68-D96 HydrophobicContact CB-CB 4.46Å; N68-E97 WeakPolarHBondContact CB-OE2 3.44Å; N68-S426 PolarHBondContact ND2-O 3.31Å; N68-P430 WeakPolarHBondContact OD1-CG 3.48Å
69	A	97.7	Very high	96.6	Very high	42 Å²	42	45.9 Å²	45.9	35%	0.347	26%	0.258	S	S	.	.	H	α-helix	trans	-53.9	-40.8	164.9	0	0	0	0	0	112.5	V65 I72 A73 E97	V65-A69 WeakPolarHBondContact O-CB 3.45Å; V65-A69 PolarHBondContact O-N 2.86Å; A69-I72 PolarHBondContact O-N 3.33Å; A69-A73 VanDerWaalsContact O-CB 3.29Å; A69-A73 WeakPolarHBondContact O-CB 3.33Å; A69-A73 PolarHBondContact O-N 3.4Å; A69-E97 PolarHBondContact N-OE2 2.87Å; A69-E97 VanDerWaalsContact N-OE2 3.11Å
70	L	97.1	Very high	96.3	Very high	47 Å²	47	41.6 Å²	41.6	25%	0.246	25%	0.247	C	C	.	.	H	α-helix	trans	-65.3	-39.9	173.4	-78.9	170.3	0	0	0	112.8	A66 G67 N68 A73 A74 F444 I447 L448	A66-L70 WeakPolarHBondContact O-CB 3.46Å; A66-L70 WeakPolarHBondContact O-CD1 3.42Å; A66-L70 WeakPolarHBondContact O-CG 3.47Å; A66-L70 PolarHBondContact O-N 3.31Å; A66-L70 VanDerWaalsContact O-N 3.12Å; G67-L70 WeakPolarHBondContact O-CB 3.45Å; G67-L70 PolarHBondContact O-N 3.46Å; N68-L70 VanDerWaalsContact C-N 3.26Å; N68-L70 PolarHBondContact O-N 2.83Å; L70-A73 PolarHBondContact O-N 3.46Å; L70-A74 VanDerWaalsContact O-CB 3.27Å; L70-A74 WeakPolarHBondContact O-CB 3.42Å; L70-A74 PolarHBondContact O-N 3.16Å; L70-F444 HydrophobicContact CB-CD1 4.31Å; L70-F444 HydrophobicContact CB-CE1 4.2Å; L70-F444 WeakPolarHBondContact O-CE1 3.43Å; L70-I447 HydrophobicContact CD2-CG2 3.92Å; L70-L448 HydrophobicContact CD1-CD2 4.46Å; L70-L448 HydrophobicContact CD2-CD2 4.38Å
71	V	97.6	Very high	96.1	Very high	0 Å²	0	41.3 Å²	41.3	0%	0	25%	0.246	C	C	.	.	H	α-helix	trans	-58.6	-49	173.8	175	0	0	0	0	110.6	G67 N68 A74 V75 I89 A93 P430 Y433 F440 F444	G67-V71 WeakPolarHBondContact O-CG2 3.25Å; G67-V71 PolarHBondContact O-N 2.78Å; G67-V71 VanDerWaalsContact O-N 3.1Å; N68-V71 WeakPolarHBondContact O-CB 3.4Å; N68-V71 PolarHBondContact O-N 2.81Å; V71-A74 PolarHBondContact O-N 3.29Å; V71-V75 WeakPolarHBondContact O-CG2 3.41Å; V71-V75 PolarHBondContact O-N 2.79Å; V71-I89 HydrophobicContact CG1-CG2 4.15Å; V71-A93 HydrophobicContact CB-CB 3.93Å; V71-A93 HydrophobicContact CG1-CB 3.69Å; V71-P430 HydrophobicContact CG2-CB 4.22Å; V71-P430 HydrophobicContact CG2-CG 4.08Å; V71-Y433 HydrophobicContact CG1-CE2 4.41Å; V71-Y433 HydrophobicContact CG2-CD2 3.81Å; V71-Y433 HydrophobicContact CG2-CE2 4.21Å; V71-F440 HydrophobicContact CG1-CE1 4.16Å; V71-F440 HydrophobicContact CG1-CZ 4.36Å; V71-F444 HydrophobicContact CG2-CE1 4.47Å; V71-F444 HydrophobicContact CG2-CZ 3.86Å
72	I	97.9	Very high	95.8	Very high	34 Å²	34	46.1 Å²	46.1	17%	0.174	26%	0.262	C	S	.	.	H	α-helix	trans	-61.2	-50.5	178.9	-64.2	164.2	0	0	0	110.1	N68 A69 A74 V75 L76 M90 A93 M94	N68-I72 WeakPolarHBondContact O-CG1 3.29Å; N68-I72 PolarHBondContact O-N 3.17Å; A69-I72 PolarHBondContact O-N 3.33Å; I72-A74 VanDerWaalsContact C-N 3.28Å; I72-A74 PolarHBondContact O-N 2.83Å; I72-V75 PolarHBondContact O-N 2.79Å; I72-L76 HydrophobicContact CG2-CD1 3.86Å; I72-L76 HydrophobicContact CG2-CG 4.46Å; I72-L76 WeakPolarHBondContact O-CG 3.08Å; I72-L76 PolarHBondContact O-N 2.71Å; I72-M90 HydrophobicContact CB-CG 4.46Å; I72-M90 HydrophobicContact CG1-CG 4.2Å; I72-M90 HydrophobicContact CG2-CG 4.26Å; I72-A93 HydrophobicContact CD1-CB 4.42Å; I72-A93 HydrophobicContact CG1-CB 3.95Å; I72-M94 HydrophobicContact CD1-CG 3.81Å; I72-M94 HydrophobicContact CG1-CG 4.36Å
73	A	96.6	Very high	95.4	Very high	38 Å²	38	45.8 Å²	45.8	31%	0.314	25%	0.253	S	S	.	.	H	α-helix	trans	-59.2	-36.3	177.6	0	0	0	0	0	112.8	A69 L70 S77 I447	A69-A73 VanDerWaalsContact O-CB 3.29Å; A69-A73 WeakPolarHBondContact O-CB 3.33Å; A69-A73 PolarHBondContact O-N 3.4Å; L70-A73 PolarHBondContact O-N 3.46Å; A73-S77 WeakPolarHBondContact O-CB 3.19Å; A73-S77 PolarHBondContact O-N 3.11Å; A73-S77 PolarHBondContact O-OG 2.92Å; A73-I447 HydrophobicContact CB-CD1 4.29Å
74	A	96.9	Very high	95.2	Very high	0 Å²	0	45.3 Å²	45.3	0%	0	25%	0.248	C	C	.	.	H	α-helix	trans	-67.2	-44.7	176.1	0	0	0	0	0	112.7	L70 V71 I72 L76 E78 L81 F440 A443 F444 I447	L70-A74 VanDerWaalsContact O-CB 3.27Å; L70-A74 WeakPolarHBondContact O-CB 3.42Å; L70-A74 PolarHBondContact O-N 3.16Å; V71-A74 PolarHBondContact O-N 3.29Å; I72-A74 VanDerWaalsContact C-N 3.28Å; I72-A74 PolarHBondContact O-N 2.83Å; A74-L76 VanDerWaalsContact C-N 3.34Å; A74-L76 PolarHBondContact O-N 2.83Å; A74-E78 VanDerWaalsContact O-CB 3.32Å; A74-E78 WeakPolarHBondContact O-CB 3.23Å; A74-E78 PolarHBondContact O-N 3.47Å; A74-L81 HydrophobicContact CB-CD1 3.82Å; A74-F440 HydrophobicContact CB-CD1 4.13Å; A74-F440 HydrophobicContact CB-CE1 4.27Å; A74-A443 HydrophobicContact CB-CB 3.86Å; A74-F444 HydrophobicContact CB-CD1 3.85Å; A74-F444 HydrophobicContact CB-CE1 3.56Å; A74-I447 HydrophobicContact CB-CD1 3.97Å
75	V	96.7	Very high	94.7	Very high	1 Å²	1	46.7 Å²	46.7	1%	0.006	26%	0.255	C	S	.	.	H	α-helix	trans	-64.3	-39.8	176.6	177	0	0	0	0	111.3	V71 I72 R82 Y87 M90 F440	V71-V75 WeakPolarHBondContact O-CG2 3.41Å; V71-V75 PolarHBondContact O-N 2.79Å; I72-V75 PolarHBondContact O-N 2.79Å; V75-R82 WeakPolarHBondContact O-CG 3.32Å; V75-Y87 HydrophobicContact CG1-CD1 4.43Å; V75-M90 HydrophobicContact CB-CB 4.29Å; V75-M90 HydrophobicContact CB-CG 4.35Å; V75-M90 HydrophobicContact CB-SD 4.2Å; V75-M90 HydrophobicContact CG1-CB 4.14Å; V75-M90 HydrophobicContact CG1-CG 4.4Å; V75-M90 HydrophobicContact CG1-SD 3.89Å; V75-M90 HydrophobicContact CG2-CB 4.31Å; V75-F440 HydrophobicContact CG2-CE1 3.91Å; V75-F440 HydrophobicContact CG2-CZ 4.02Å
76	L	95.6	Very high	94.6	Very high	100 Å²	100	45.8 Å²	45.8	52%	0.524	25%	0.248	S	C	.	.	H	α-helix	trans	-73.1	-39.5	-179.5	-66.3	175.8	0	0	0	113.5	I72 A74 R82 M90	I72-L76 HydrophobicContact CG2-CD1 3.86Å; I72-L76 HydrophobicContact CG2-CG 4.46Å; I72-L76 WeakPolarHBondContact O-CG 3.08Å; I72-L76 PolarHBondContact O-N 2.71Å; A74-L76 VanDerWaalsContact C-N 3.34Å; A74-L76 PolarHBondContact O-N 2.83Å; L76-R82 WeakPolarHBondContact O-CD 3.22Å; L76-M90 HydrophobicContact CD2-SD 3.83Å; L76-M90 HydrophobicContact CG-SD 4.08Å
77	S	93.2	Very high	94.5	Very high	72 Å²	72	44.6 Å²	44.6	50%	0.503	23%	0.232	S	C	.	.	H	α-helix	trans	-91.6	-30.5	-172.3	67.3	0	0	0	0	115	A73	A73-S77 WeakPolarHBondContact O-CB 3.19Å; A73-S77 PolarHBondContact O-N 3.11Å; A73-S77 PolarHBondContact O-OG 2.92Å
78	E	94.3	Very high	94.5	Very high	31 Å²	31	44.1 Å²	44.1	15%	0.145	23%	0.227	C	C	.	.			trans	-93.2	118	-172.3	-176.4	46	-109	0	0	112.2	A74 A80 L81 R82 A443 K446	A74-E78 VanDerWaalsContact O-CB 3.32Å; A74-E78 WeakPolarHBondContact O-CB 3.23Å; A74-E78 PolarHBondContact O-N 3.47Å; E78-A80 HydrophobicContact CG-CB 4.06Å; E78-A80 PolarHBondContact O-N 2.81Å; E78-A80 VanDerWaalsContact O-N 3.1Å; E78-A80 PolarHBondContact OE1-N 3.08Å; E78-L81 HydrophobicContact CB-CB 4.25Å; E78-L81 HydrophobicContact CB-CD1 4.13Å; E78-L81 HydrophobicContact CB-CG 4.19Å; E78-L81 HydrophobicContact CG-CD1 4.44Å; E78-L81 HydrophobicContact CG-CG 4.2Å; E78-L81 PolarHBondContact O-N 2.83Å; E78-R82 PolarHBondContact O-N 3.14Å; E78-R82 VanDerWaalsContact O-N 3.14Å; E78-A443 HydrophobicContact CB-CB 4.08Å; E78-A443 HydrophobicContact CG-CB 4.14Å; E78-K446 IonicContact OE1-NZ 2.74Å; E78-K446 WeakPolarHBondContact OE2-CD 3.49Å; E78-K446 WeakPolarHBondContact OE2-CE 3.08Å; E78-K446 IonicContact OE2-NZ 3.8Å; E78-K446 PolarHBondContact OE2-NZ 2.76Å
79	K	91.6	Very high	94.5	Very high	168 Å²	168	44.6 Å²	44.6	73%	0.73	23%	0.229	S	C	*	.	T	Hydrogen-bonded Turn	trans	-55.1	-33.9	179.7	-66.8	-171.6	-179.6	-178	0	112.1	L81	K79-L81 VanDerWaalsContact C-N 3.3Å; K79-L81 PolarHBondContact O-N 2.99Å
80	A	89.9	Confident	94.5	Very high	42 Å²	42	44 Å²	44	35%	0.347	22%	0.219	S	C	.	.	T	Hydrogen-bonded Turn	trans	-68.6	-25.3	177.1	0	0	0	0	0	114.3	E78	E78-A80 HydrophobicContact CG-CB 4.06Å; E78-A80 PolarHBondContact O-N 2.81Å; E78-A80 VanDerWaalsContact O-N 3.1Å; E78-A80 PolarHBondContact OE1-N 3.08Å
81	L	91.9	Very high	94.5	Very high	0 Å²	0	42 Å²	42	0%	0	21%	0.209	C	C	.	.	T	Hydrogen-bonded Turn	trans	-97.8	-11.6	-179.3	-63.6	178.9	0	0	0	113.5	A74 E78 K79 R83 Y86 D439 F440 A443	A74-L81 HydrophobicContact CB-CD1 3.82Å; E78-L81 HydrophobicContact CB-CB 4.25Å; E78-L81 HydrophobicContact CB-CD1 4.13Å; E78-L81 HydrophobicContact CB-CG 4.19Å; E78-L81 HydrophobicContact CG-CD1 4.44Å; E78-L81 HydrophobicContact CG-CG 4.2Å; E78-L81 PolarHBondContact O-N 2.83Å; K79-L81 VanDerWaalsContact C-N 3.3Å; K79-L81 PolarHBondContact O-N 2.99Å; L81-R83 PolarHBondContact O-N 3.48Å; L81-Y86 HydrophobicContact CB-CD2 4.37Å; L81-Y86 HydrophobicContact CD2-CD1 4.13Å; L81-Y86 HydrophobicContact CD2-CD2 4.21Å; L81-Y86 HydrophobicContact CD2-CE1 3.67Å; L81-Y86 HydrophobicContact CD2-CE2 3.72Å; L81-Y86 HydrophobicContact CD2-CG 4.4Å; L81-Y86 VanDerWaalsContact CD2-CZ 3.44Å; L81-Y86 WeakPolarHBondContact O-CB 3.32Å; L81-Y86 WeakPolarHBondContact O-CD2 3.17Å; L81-Y86 VanDerWaalsContact O-CG 3.31Å; L81-D439 HydrophobicContact CD2-CB 3.88Å; L81-F440 HydrophobicContact CD1-CD1 3.66Å; L81-F440 HydrophobicContact CD1-CE1 3.78Å; L81-F440 HydrophobicContact CD1-CG 4.39Å; L81-F440 HydrophobicContact CD2-CD1 4.48Å; L81-F440 HydrophobicContact CD2-CE1 4.46Å; L81-A443 HydrophobicContact CD1-CB 3.57Å
82	R	90.5	Very high	94.6	Very high	133 Å²	133	42 Å²	42	50%	0.502	21%	0.21	S	C	.	.			trans	-74.4	40.3	173.5	-64.6	-172.7	-45.5	-179.3	9.6	114.1	V75 L76 E78	V75-R82 WeakPolarHBondContact O-CG 3.32Å; L76-R82 WeakPolarHBondContact O-CD 3.22Å; E78-R82 PolarHBondContact O-N 3.14Å; E78-R82 VanDerWaalsContact O-N 3.14Å
83	R	90	Very high	94.6	Very high	103 Å²	103	40.5 Å²	40.5	39%	0.389	20%	0.202	S	C	.	.	S	Bend	trans	-98	150.1	173.8	-54.9	177.3	171.9	-152.6	-14	109.9	L81 H85 Y86	L81-R83 PolarHBondContact O-N 3.48Å; R83-H85 VanDerWaalsContact C-N 3.3Å; R83-H85 PolarHBondContact O-N 2.97Å; R83-Y86 HydrophobicContact CB-CD2 3.92Å; R83-Y86 HydrophobicContact CB-CE2 4.36Å; R83-Y86 HydrophobicContact CG-CD2 4.43Å; R83-Y86 PolarHBondContact O-N 2.89Å
84	N	91.3	Very high	94.7	Very high	39 Å²	39	43.3 Å²	43.3	21%	0.209	21%	0.21	C	C	.	.	T	Hydrogen-bonded Turn	trans	-57.2	-33.5	-166	-60.7	-15.6	0	0	0	114.8	Y86 Y87 R161 K163 I166	N84-Y86 PolarHBondContact O-N 3.33Å; N84-Y87 WeakPolarHBondContact O-CD2 3.26Å; N84-Y87 PolarHBondContact O-N 2.82Å; N84-R161 HydrophobicContact CB-CG 4.4Å; N84-R161 PolarHBondContact ND2-O 3.14Å; N84-K163 WeakPolarHBondContact OD1-CG 3.46Å; N84-I166 HydrophobicContact CB-CG1 4.11Å; N84-I166 WeakPolarHBondContact O-CG2 2.98Å
85	H	89.3	Confident	94.7	Very high	30 Å²	30	43.3 Å²	43.3	14%	0.139	21%	0.21	C	C	.	.	T	Hydrogen-bonded Turn	trans	-69.7	-26.5	176	48	-101.3	0	0	0	115	R83 Y87 L88 R161	R83-H85 VanDerWaalsContact C-N 3.3Å; R83-H85 PolarHBondContact O-N 2.97Å; H85-Y87 PolarHBondContact O-N 3.32Å; H85-L88 WeakPolarHBondContact O-CB 3.41Å; H85-L88 PolarHBondContact O-N 3Å; H85-L88 VanDerWaalsContact O-N 3.13Å; H85-R161 PolarHBondContact ND1-NH1 2.97Å
86	Y	94.6	Very high	94.8	Very high	15 Å²	15	43.4 Å²	43.4	6%	0.059	21%	0.21	C	C	.	.	H	α-helix	trans	-69.7	-17.6	-179.3	-73.6	-67.4	0	0	0	112.4	L81 R83 N84 L88 I89 M90 D439 F440	L81-Y86 HydrophobicContact CB-CD2 4.37Å; L81-Y86 HydrophobicContact CD2-CD1 4.13Å; L81-Y86 HydrophobicContact CD2-CD2 4.21Å; L81-Y86 HydrophobicContact CD2-CE1 3.67Å; L81-Y86 HydrophobicContact CD2-CE2 3.72Å; L81-Y86 HydrophobicContact CD2-CG 4.4Å; L81-Y86 VanDerWaalsContact CD2-CZ 3.44Å; L81-Y86 WeakPolarHBondContact O-CB 3.32Å; L81-Y86 WeakPolarHBondContact O-CD2 3.17Å; L81-Y86 VanDerWaalsContact O-CG 3.31Å; R83-Y86 HydrophobicContact CB-CD2 3.92Å; R83-Y86 HydrophobicContact CB-CE2 4.36Å; R83-Y86 HydrophobicContact CG-CD2 4.43Å; R83-Y86 PolarHBondContact O-N 2.89Å; N84-Y86 PolarHBondContact O-N 3.33Å; Y86-L88 VanDerWaalsContact C-N 3.3Å; Y86-L88 PolarHBondContact O-N 3.45Å; Y86-I89 HydrophobicContact CD1-CD1 3.88Å; Y86-I89 HydrophobicContact CE1-CD1 4.22Å; Y86-I89 PolarHBondContact O-N 3.13Å; Y86-M90 WeakPolarHBondContact O-CB 3.26Å; Y86-M90 PolarHBondContact O-N 3.21Å; Y86-D439 PolarHBondContact OH-OD2 3.29Å; Y86-F440 AromaticContact CD1-CE2 3.87Å; Y86-F440 HydrophobicContact CD1-CE2 3.87Å; Y86-F440 AromaticContact CD1-CZ 3.78Å; Y86-F440 HydrophobicContact CD1-CZ 3.78Å; Y86-F440 HydrophobicContact CE1-CD2 4.38Å; Y86-F440 AromaticContact CE1-CE2 3.63Å; Y86-F440 HydrophobicContact CE1-CE2 3.63Å; Y86-F440 AromaticContact CE1-CZ 3.98Å; Y86-F440 HydrophobicContact CE1-CZ 3.98Å
87	Y	96.9	Very high	94.9	Very high	31 Å²	31	40.1 Å²	40.1	12%	0.122	19%	0.192	C	C	.	.	H	α-helix	trans	-66.1	-29.4	170.7	-62.4	-58	0	0	0	113	V75 N84 H85 M90 S91 F167	V75-Y87 HydrophobicContact CG1-CD1 4.43Å; N84-Y87 WeakPolarHBondContact O-CD2 3.26Å; N84-Y87 PolarHBondContact O-N 2.82Å; H85-Y87 PolarHBondContact O-N 3.32Å; Y87-M90 HydrophobicContact CD1-CE 4.01Å; Y87-M90 HydrophobicContact CD1-SD 4.35Å; Y87-S91 WeakPolarHBondContact O-CB 3.3Å; Y87-S91 PolarHBondContact O-N 2.85Å; Y87-F167 HydrophobicContact CD1-CZ 4.44Å; Y87-F167 HydrophobicContact CD2-CE2 4.4Å; Y87-F167 HydrophobicContact CD2-CZ 4.43Å; Y87-F167 HydrophobicContact CG-CZ 4.32Å
88	L	97.2	Very high	95.1	Very high	1 Å²	1	37.9 Å²	37.9	1%	0.005	17%	0.174	C	C	.	.	H	α-helix	trans	-67.1	-40.3	171.2	-67.2	171.8	0	0	0	111.3	H85 Y86 S91 L92 A143 I144 D147 I166 M169 I170	H85-L88 WeakPolarHBondContact O-CB 3.41Å; H85-L88 PolarHBondContact O-N 3Å; H85-L88 VanDerWaalsContact O-N 3.13Å; Y86-L88 VanDerWaalsContact C-N 3.3Å; Y86-L88 PolarHBondContact O-N 3.45Å; L88-S91 PolarHBondContact O-N 3.08Å; L88-L92 PolarHBondContact O-N 3Å; L88-A143 HydrophobicContact CD2-CB 4.1Å; L88-I144 HydrophobicContact CB-CD1 4.31Å; L88-I144 HydrophobicContact CB-CG1 3.7Å; L88-I144 HydrophobicContact CD1-CG1 4.13Å; L88-D147 HydrophobicContact CD1-CB 4Å; L88-I166 HydrophobicContact CD1-CD1 4.11Å; L88-I166 HydrophobicContact CD2-CG2 4.08Å; L88-I166 HydrophobicContact CG-CD1 4.42Å; L88-I166 HydrophobicContact CG-CG2 3.88Å; L88-M169 HydrophobicContact CD1-CE 4.27Å; L88-M169 HydrophobicContact CD2-CB 4.3Å; L88-I170 HydrophobicContact CD2-CD1 4.47Å; L88-I170 HydrophobicContact CD2-CG1 3.81Å
89	I	96.9	Very high	95.3	Very high	10 Å²	10	36.6 Å²	36.6	5%	0.051	17%	0.168	C	C	.	.	H	α-helix	trans	-69	-37.5	177.4	-62.8	175.4	0	0	0	110.9	V71 Y86 L92 A93 I144 L369 Y433 F440	V71-I89 HydrophobicContact CG1-CG2 4.15Å; Y86-I89 HydrophobicContact CD1-CD1 3.88Å; Y86-I89 HydrophobicContact CE1-CD1 4.22Å; Y86-I89 PolarHBondContact O-N 3.13Å; I89-L92 PolarHBondContact O-N 2.89Å; I89-A93 WeakPolarHBondContact O-CB 3.39Å; I89-A93 PolarHBondContact O-N 3.44Å; I89-I144 HydrophobicContact CG1-CD1 4.15Å; I89-L369 HydrophobicContact CD1-CD2 4Å; I89-Y433 HydrophobicContact CG2-CE1 4.32Å; I89-Y433 HydrophobicContact CG2-CE2 3.91Å; I89-F440 HydrophobicContact CD1-CE2 4.36Å; I89-F440 HydrophobicContact CG2-CE2 4.19Å; I89-F440 HydrophobicContact CG2-CZ 3.88Å
90	M	97.8	Very high	95.6	Very high	29 Å²	29	28.6 Å²	28.6	14%	0.143	13%	0.134	C	C	.	.	H	α-helix	trans	-64.3	-41.3	173.8	-169.7	-177.8	81.6	0	0	111.7	I72 V75 L76 Y86 Y87 A93 M94	I72-M90 HydrophobicContact CB-CG 4.46Å; I72-M90 HydrophobicContact CG1-CG 4.2Å; I72-M90 HydrophobicContact CG2-CG 4.26Å; V75-M90 HydrophobicContact CB-CB 4.29Å; V75-M90 HydrophobicContact CB-CG 4.35Å; V75-M90 HydrophobicContact CB-SD 4.2Å; V75-M90 HydrophobicContact CG1-CB 4.14Å; V75-M90 HydrophobicContact CG1-CG 4.4Å; V75-M90 HydrophobicContact CG1-SD 3.89Å; V75-M90 HydrophobicContact CG2-CB 4.31Å; L76-M90 HydrophobicContact CD2-SD 3.83Å; L76-M90 HydrophobicContact CG-SD 4.08Å; Y86-M90 WeakPolarHBondContact O-CB 3.26Å; Y86-M90 PolarHBondContact O-N 3.21Å; Y87-M90 HydrophobicContact CD1-CE 4.01Å; Y87-M90 HydrophobicContact CD1-SD 4.35Å; M90-A93 PolarHBondContact O-N 2.8Å; M90-M94 WeakPolarHBondContact O-CG 3.4Å; M90-M94 PolarHBondContact O-N 2.83Å
91	S	98.3	Very high	96	Very high	5 Å²	5	31.2 Å²	31.2	4%	0.035	14%	0.142	C	C	.	.	H	α-helix	trans	-71.3	-33.1	177.8	-168.2	0	0	0	0	112.7	Y87 L88 M94 A95 H140 I170 W174	Y87-S91 WeakPolarHBondContact O-CB 3.3Å; Y87-S91 PolarHBondContact O-N 2.85Å; L88-S91 PolarHBondContact O-N 3.08Å; S91-M94 PolarHBondContact O-N 3.32Å; S91-A95 PolarHBondContact O-N 3.13Å; S91-H140 VanDerWaalsContact CB-NE2 3.28Å; S91-H140 WeakPolarHBondContact CB-NE2 3.37Å; S91-H140 PolarHBondContact OG-CE1 3.25Å; S91-H140 PolarHBondContact OG-NE2 3.34Å; S91-I170 WeakPolarHBondContact OG-CG2 3.26Å; S91-W174 PolarHBondContact OG-NE1 2.88Å
92	L	98.3	Very high	96.3	Very high	1 Å²	1	34.7 Å²	34.7	1%	0.005	16%	0.159	C	C	.	.	H	α-helix	trans	-61	-47.6	166.4	175.7	61.6	0	0	0	111.2	L88 I89 M94 A95 D96 H140 L141 I144 V372	L88-L92 PolarHBondContact O-N 3Å; I89-L92 PolarHBondContact O-N 2.89Å; L92-M94 PolarHBondContact O-N 2.93Å; L92-A95 WeakPolarHBondContact O-CB 3.35Å; L92-A95 PolarHBondContact O-N 2.85Å; L92-D96 PolarHBondContact O-N 3.41Å; L92-H140 HydrophobicContact CB-CB 4.03Å; L92-H140 HydrophobicContact CD1-CB 4.1Å; L92-L141 HydrophobicContact CD2-CD2 3.99Å; L92-I144 HydrophobicContact CD2-CD1 4.21Å; L92-V372 HydrophobicContact CD2-CG1 4.44Å
93	A	98.4	Very high	96.6	Very high	2 Å²	2	28.3 Å²	28.3	2%	0.017	14%	0.136	C	C	.	.	H	α-helix	trans	-61.8	-29.4	176.3	0	0	0	0	0	112.8	N68 V71 I72 I89 M90 D96 E97	N68-A93 HydrophobicContact CB-CB 4.23Å; V71-A93 HydrophobicContact CB-CB 3.93Å; V71-A93 HydrophobicContact CG1-CB 3.69Å; I72-A93 HydrophobicContact CD1-CB 4.42Å; I72-A93 HydrophobicContact CG1-CB 3.95Å; I89-A93 WeakPolarHBondContact O-CB 3.39Å; I89-A93 PolarHBondContact O-N 3.44Å; M90-A93 PolarHBondContact O-N 2.8Å; A93-D96 PolarHBondContact O-N 3.47Å; A93-E97 VanDerWaalsContact O-CB 3.29Å; A93-E97 WeakPolarHBondContact O-CB 3.43Å; A93-E97 PolarHBondContact O-N 3.24Å
94	M	98.3	Very high	96.9	Very high	97 Å²	97	23.4 Å²	23.4	48%	0.478	12%	0.117	S	C	.	.	H	α-helix	trans	-69.8	-33.5	171.8	-70	172.7	67.2	0	0	112.9	I72 M90 S91 L92 M98	I72-M94 HydrophobicContact CD1-CG 3.81Å; I72-M94 HydrophobicContact CG1-CG 4.36Å; M90-M94 WeakPolarHBondContact O-CG 3.4Å; M90-M94 PolarHBondContact O-N 2.83Å; S91-M94 PolarHBondContact O-N 3.32Å; L92-M94 PolarHBondContact O-N 2.93Å; M94-M98 PolarHBondContact O-N 2.94Å
95	A	98.4	Very high	97.2	Very high	0 Å²	0	23.8 Å²	23.8	0%	0	12%	0.122	C	C	.	.	H	α-helix	trans	-69.6	-41.4	171.7	0	0	0	0	0	111.2	S91 L92 M98 V99 A136 S137 W174	S91-A95 PolarHBondContact O-N 3.13Å; L92-A95 WeakPolarHBondContact O-CB 3.35Å; L92-A95 PolarHBondContact O-N 2.85Å; A95-M98 WeakPolarHBondContact O-CB 3.38Å; A95-M98 PolarHBondContact O-N 3.33Å; A95-V99 PolarHBondContact O-N 2.89Å; A95-V99 VanDerWaalsContact O-N 3.12Å; A95-A136 HydrophobicContact CB-CB 4.09Å; A95-S137 WeakPolarHBondContact CB-OG 3.42Å; A95-W174 HydrophobicContact CB-CH2 4.01Å; A95-W174 HydrophobicContact CB-CZ2 4.24Å
96	D	98.4	Very high	97.6	Very high	2 Å²	2	24.1 Å²	24.1	1%	0.011	12%	0.124	C	C	.	.	H	α-helix	trans	-67.4	-33.2	174.9	-68.6	-37.6	0	0	0	112.8	T64 N68 L92 A93 M98 V99 G100 S137 S426 N429	T64-D96 WeakPolarHBondContact CG2-O 3.29Å; N68-D96 HydrophobicContact CB-CB 4.46Å; L92-D96 PolarHBondContact O-N 3.41Å; A93-D96 PolarHBondContact O-N 3.47Å; D96-M98 VanDerWaalsContact C-N 3.32Å; D96-V99 WeakPolarHBondContact O-CB 3.32Å; D96-V99 PolarHBondContact O-N 3.23Å; D96-G100 PolarHBondContact O-N 3.01Å; D96-S137 PolarHBondContact OD1-OG 3.21Å; D96-S426 WeakPolarHBondContact OD1-CB 3.24Å; D96-S426 PolarHBondContact OD1-OG 3Å; D96-N429 PolarHBondContact OD2-ND2 2.99Å
97	E	97.7	Very high	97.6	Very high	31 Å²	31	23.4 Å²	23.4	15%	0.145	12%	0.121	C	C	.	.	H	α-helix	trans	-62.9	-39.7	171.1	-167.1	74.2	-173.5	0	0	111.1	V65 N68 A69 A93 V99 G100 L101	V65-E97 VanDerWaalsContact O-OE2 3.12Å; N68-E97 WeakPolarHBondContact CB-OE2 3.44Å; A69-E97 PolarHBondContact N-OE2 2.87Å; A69-E97 VanDerWaalsContact N-OE2 3.11Å; A93-E97 VanDerWaalsContact O-CB 3.29Å; A93-E97 WeakPolarHBondContact O-CB 3.43Å; A93-E97 PolarHBondContact O-N 3.24Å; E97-V99 VanDerWaalsContact C-N 3.33Å; E97-V99 PolarHBondContact O-N 2.88Å; E97-G100 PolarHBondContact O-N 3.03Å; E97-G100 VanDerWaalsContact O-N 3.14Å; E97-L101 HydrophobicContact CG-CD1 3.84Å; E97-L101 HydrophobicContact CG-CG 4.35Å; E97-L101 WeakPolarHBondContact O-CB 3.28Å; E97-L101 WeakPolarHBondContact O-CG 3.2Å; E97-L101 PolarHBondContact O-N 3.47Å
98	M	97.9	Very high	97.6	Very high	26 Å²	26	22.5 Å²	22.5	13%	0.128	12%	0.12	C	C	.	.	H	α-helix	trans	-64.3	-35.7	174.8	-167	172	72.5	0	0	112	M94 A95 D96 L102 V103 F129 L132 A133 W174	M94-M98 PolarHBondContact O-N 2.94Å; A95-M98 WeakPolarHBondContact O-CB 3.38Å; A95-M98 PolarHBondContact O-N 3.33Å; D96-M98 VanDerWaalsContact C-N 3.32Å; M98-L102 HydrophobicContact CG-CD1 3.89Å; M98-L102 HydrophobicContact CG-CG 4.42Å; M98-L102 WeakPolarHBondContact O-CB 3.39Å; M98-L102 PolarHBondContact O-N 3.18Å; M98-V103 PolarHBondContact O-N 3.44Å; M98-F129 HydrophobicContact CE-CD1 4.24Å; M98-F129 HydrophobicContact CG-CD1 4.04Å; M98-F129 HydrophobicContact SD-CD1 3.58Å; M98-F129 VanDerWaalsContact SD-CD1 3.58Å; M98-F129 HydrophobicContact SD-CE1 3.9Å; M98-L132 HydrophobicContact CE-CB 4.13Å; M98-L132 HydrophobicContact CE-CD2 3.95Å; M98-L132 HydrophobicContact CE-CG 3.82Å; M98-L132 HydrophobicContact SD-CD2 4.28Å; M98-A133 VanDerWaalsContact CE-CA 3.46Å; M98-A133 HydrophobicContact CE-CB 3.51Å; M98-W174 HydrophobicContact CE-CH2 4.31Å; M98-W174 HydrophobicContact CE-CZ3 4.19Å
99	V	98.3	Very high	97.5	Very high	3 Å²	3	26.6 Å²	26.6	2%	0.018	14%	0.136	C	C	.	.	I	π-helix	trans	-61.2	-45.5	169.4	179.2	0	0	0	0	111	A95 D96 E97 V103 T104 A133 Y423	A95-V99 PolarHBondContact O-N 2.89Å; A95-V99 VanDerWaalsContact O-N 3.12Å; D96-V99 WeakPolarHBondContact O-CB 3.32Å; D96-V99 PolarHBondContact O-N 3.23Å; E97-V99 VanDerWaalsContact C-N 3.33Å; E97-V99 PolarHBondContact O-N 2.88Å; V99-V103 PolarHBondContact O-N 3Å; V99-T104 HydrophobicContact CG1-CG2 3.69Å; V99-T104 WeakPolarHBondContact O-CB 3.33Å; V99-T104 PolarHBondContact O-N 2.98Å; V99-T104 PolarHBondContact O-OG1 3.34Å; V99-A133 HydrophobicContact CG2-CB 3.51Å; V99-Y423 HydrophobicContact CG1-CD1 3.92Å
100	G	97.8	Very high	97.3	Very high	1 Å²	1	27.8 Å²	27.8	1%	0.01	14%	0.141	C	C	.	.	I	π-helix	trans	-67.8	-36.5	-179.7	0	0	0	0	0	114.5	D96 E97 T104 P105	D96-G100 PolarHBondContact O-N 3.01Å; E97-G100 PolarHBondContact O-N 3.03Å; E97-G100 VanDerWaalsContact O-N 3.14Å; G100-T104 WeakPolarHBondContact CA-OG1 3.34Å; G100-T104 PolarHBondContact O-OG1 2.86Å; G100-P105 WeakPolarHBondContact O-CD 3.38Å
101	L	97.9	Very high	97	Very high	97 Å²	97	27.6 Å²	27.6	51%	0.508	14%	0.14	S	C	.	.	I	π-helix	trans	-92.7	-34.8	-174.1	-67.4	176.8	0	0	0	114.5	V65 E97	V65-L101 HydrophobicContact CG1-CD2 4.03Å; V65-L101 HydrophobicContact CG2-CD2 3.77Å; V65-L101 HydrophobicContact CG2-CG 4.11Å; E97-L101 HydrophobicContact CG-CD1 3.84Å; E97-L101 HydrophobicContact CG-CG 4.35Å; E97-L101 WeakPolarHBondContact O-CB 3.28Å; E97-L101 WeakPolarHBondContact O-CG 3.2Å; E97-L101 PolarHBondContact O-N 3.47Å
102	L	97.1	Very high	96.6	Very high	72 Å²	72	30.4 Å²	30.4	38%	0.377	16%	0.157	S	C	.	.	I	π-helix	trans	-115	-38	-171.2	-55.8	-176.2	0	0	0	113.4	M98 L106 F129	M98-L102 HydrophobicContact CG-CD1 3.89Å; M98-L102 HydrophobicContact CG-CG 4.42Å; M98-L102 WeakPolarHBondContact O-CB 3.39Å; M98-L102 PolarHBondContact O-N 3.18Å; L102-L106 WeakPolarHBondContact O-CD1 3.33Å; L102-L106 WeakPolarHBondContact O-CG 3.37Å; L102-F129 HydrophobicContact CB-CB 4.48Å; L102-F129 HydrophobicContact CB-CG 4.45Å; L102-F129 HydrophobicContact CD1-CD1 3.77Å; L102-F129 HydrophobicContact CD1-CD2 3.92Å; L102-F129 HydrophobicContact CD1-CE1 3.72Å; L102-F129 HydrophobicContact CD1-CE2 3.87Å; L102-F129 HydrophobicContact CD1-CG 3.88Å; L102-F129 HydrophobicContact CD1-CZ 3.78Å
103	V	98.1	Very high	96.2	Very high	0 Å²	0	34.1 Å²	34.1	0%	0	18%	0.177	C	C	.	.	I	π-helix	trans	-89.2	-57.3	-170.5	-175.1	0	0	0	0	111.6	M98 V99 L106 A107 F129 D130 Y423	M98-V103 PolarHBondContact O-N 3.44Å; V99-V103 PolarHBondContact O-N 3Å; V103-L106 PolarHBondContact O-N 3.45Å; V103-A107 PolarHBondContact O-N 2.76Å; V103-F129 HydrophobicContact CG2-CB 4.01Å; V103-D130 HydrophobicContact CG1-CB 3.7Å; V103-D130 HydrophobicContact CG2-CB 4.41Å; V103-Y423 HydrophobicContact CG1-CD1 4.48Å; V103-Y423 HydrophobicContact CG1-CE1 3.55Å; V103-Y423 WeakPolarHBondContact CG1-OH 3.48Å
104	T	97	Very high	95.7	Very high	0 Å²	0	40.8 Å²	40.8	0%	0	21%	0.207	C	C	.	.	H	α-helix	trans	-66.2	-30.6	-174.5	48.2	0	0	0	0	114.9	V99 G100 A108 W420 Y423	V99-T104 HydrophobicContact CG1-CG2 3.69Å; V99-T104 WeakPolarHBondContact O-CB 3.33Å; V99-T104 PolarHBondContact O-N 2.98Å; V99-T104 PolarHBondContact O-OG1 3.34Å; G100-T104 WeakPolarHBondContact CA-OG1 3.34Å; G100-T104 PolarHBondContact O-OG1 2.86Å; T104-A108 VanDerWaalsContact O-CB 3.25Å; T104-A108 WeakPolarHBondContact O-CB 3.38Å; T104-A108 PolarHBondContact O-N 2.84Å; T104-W420 HydrophobicContact CG2-CZ3 4.37Å; T104-Y423 HydrophobicContact CG2-CD1 4Å; T104-Y423 HydrophobicContact CG2-CD2 3.72Å; T104-Y423 HydrophobicContact CG2-CE2 4.34Å; T104-Y423 HydrophobicContact CG2-CG 3.52Å
105	P	96.8	Very high	95.3	Very high	47 Å²	47	42.4 Å²	42.4	31%	0.305	21%	0.212	S	C	.	.	H	α-helix	trans	-66.9	-36.3	171.9	-23	36.2	0	0	0	113.1	I61 G100 Y109	I61-P105 HydrophobicContact CD1-CG 4.32Å; G100-P105 WeakPolarHBondContact O-CD 3.38Å; P105-Y109 WeakPolarHBondContact O-CB 3.48Å; P105-Y109 PolarHBondContact O-N 2.97Å
106	L	96.6	Very high	95	Very high	37 Å²	37	42.4 Å²	42.4	19%	0.194	21%	0.212	C	C	.	.	H	α-helix	trans	-73.1	-39.4	177	-65.7	-179.5	0	0	0	111.5	L102 V103 Y109 Y110 W116 I118 W126	L102-L106 WeakPolarHBondContact O-CD1 3.33Å; L102-L106 WeakPolarHBondContact O-CG 3.37Å; V103-L106 PolarHBondContact O-N 3.45Å; L106-Y109 WeakPolarHBondContact O-CB 3.49Å; L106-Y109 PolarHBondContact O-N 3.27Å; L106-Y110 PolarHBondContact O-N 3.38Å; L106-W116 HydrophobicContact CB-CH2 4.17Å; L106-W116 HydrophobicContact CB-CZ3 4.42Å; L106-W116 HydrophobicContact CD2-CH2 4.25Å; L106-I118 HydrophobicContact CD2-CD1 3.98Å; L106-W126 HydrophobicContact CB-CB 4.28Å; L106-W126 HydrophobicContact CB-CD2 4.2Å; L106-W126 HydrophobicContact CB-CG 3.91Å; L106-W126 HydrophobicContact CD1-CB 3.76Å; L106-W126 HydrophobicContact CD1-CG 4.24Å
107	A	95.8	Very high	94.8	Very high	0 Å²	0	46 Å²	46	0%	0	23%	0.234	C	C	.	.	H	α-helix	trans	-62.7	-44.7	171.4	0	0	0	0	0	112.3	V103 Y109 Y110 D111 W126 W420 Y423	V103-A107 PolarHBondContact O-N 2.76Å; A107-Y109 VanDerWaalsContact C-N 3.32Å; A107-Y109 PolarHBondContact O-N 3.48Å; A107-Y110 PolarHBondContact O-N 2.84Å; A107-D111 PolarHBondContact O-N 3.19Å; A107-W126 HydrophobicContact CB-CH2 4.42Å; A107-W126 HydrophobicContact CB-CZ2 3.59Å; A107-W420 HydrophobicContact CB-CZ2 4.26Å; A107-Y423 HydrophobicContact CB-CD2 4.42Å; A107-Y423 HydrophobicContact CB-CE2 3.52Å
108	A	95.7	Very high	94.7	Very high	12 Å²	12	47.8 Å²	47.8	10%	0.099	24%	0.244	C	C	.	.	H	α-helix	trans	-59.7	-41.5	174.6	0	0	0	0	0	112	F57 I61 T104 V112 W420	F57-A108 HydrophobicContact CB-CB 4.03Å; F57-A108 HydrophobicContact CD2-CB 3.85Å; F57-A108 HydrophobicContact CG-CB 4.21Å; I61-A108 HydrophobicContact CD1-CB 4.29Å; T104-A108 VanDerWaalsContact O-CB 3.25Å; T104-A108 WeakPolarHBondContact O-CB 3.38Å; T104-A108 PolarHBondContact O-N 2.84Å; A108-V112 VanDerWaalsContact O-CB 3.29Å; A108-V112 WeakPolarHBondContact O-CB 3.38Å; A108-V112 WeakPolarHBondContact O-CG2 3.43Å; A108-V112 PolarHBondContact O-N 2.9Å; A108-W420 HydrophobicContact CB-CH2 3.99Å; A108-W420 HydrophobicContact CB-CZ2 4.09Å
109	Y	95.1	Very high	94.5	Very high	86 Å²	86	47.5 Å²	47.5	34%	0.337	25%	0.248	S	C	.	.	H	α-helix	trans	-59.8	-47.1	174.2	-178.1	-84.4	0	0	0	111.6	P105 L106 A107 N113 T117 I118	P105-Y109 WeakPolarHBondContact O-CB 3.48Å; P105-Y109 PolarHBondContact O-N 2.97Å; L106-Y109 WeakPolarHBondContact O-CB 3.49Å; L106-Y109 PolarHBondContact O-N 3.27Å; A107-Y109 VanDerWaalsContact C-N 3.32Å; A107-Y109 PolarHBondContact O-N 3.48Å; Y109-N113 WeakPolarHBondContact CD2-ND2 3.4Å; Y109-N113 HydrophobicContact CE1-CB 4.48Å; Y109-N113 WeakPolarHBondContact CE2-ND2 3.5Å; Y109-N113 WeakPolarHBondContact O-CB 3.49Å; Y109-N113 PolarHBondContact O-N 3.37Å; Y109-N113 PolarHBondContact O-ND2 2.92Å; Y109-T117 PolarHBondContact OH-OG1 3.09Å; Y109-I118 HydrophobicContact CD1-CD1 3.6Å; Y109-I118 HydrophobicContact CD1-CG1 3.8Å; Y109-I118 HydrophobicContact CD2-CD1 4.46Å; Y109-I118 HydrophobicContact CE1-CD1 3.8Å; Y109-I118 HydrophobicContact CE1-CG1 3.46Å; Y109-I118 VanDerWaalsContact CE1-CG1 3.46Å; Y109-I118 HydrophobicContact CG-CD1 3.97Å
110	Y	93.7	Very high	94.3	Very high	36 Å²	36	49 Å²	49	14%	0.141	26%	0.256	C	S	.	.	H	α-helix	trans	-63.2	-48.7	-179	-176.1	-121.4	0	0	0	112	L106 A107 V112 N113 Q114 W116 W126	L106-Y110 PolarHBondContact O-N 3.38Å; A107-Y110 PolarHBondContact O-N 2.84Å; Y110-V112 PolarHBondContact O-N 2.78Å; Y110-N113 PolarHBondContact O-N 3.11Å; Y110-Q114 WeakPolarHBondContact O-CA 3.42Å; Y110-Q114 PolarHBondContact O-N 3.36Å; Y110-W116 HydrophobicContact CD2-CB 3.77Å; Y110-W116 AromaticContact CD2-CE3 3.89Å; Y110-W116 HydrophobicContact CD2-CE3 3.89Å; Y110-W116 HydrophobicContact CE2-CB 3.77Å; Y110-W116 HydrophobicContact CG-CE3 4.15Å; Y110-W126 AromaticContact CD1-CH2 3.76Å; Y110-W126 HydrophobicContact CD1-CH2 3.76Å; Y110-W126 AromaticContact CD1-CZ3 3.97Å; Y110-W126 HydrophobicContact CD1-CZ3 3.97Å; Y110-W126 HydrophobicContact CG-CH2 4.09Å; Y110-W126 AromaticContact CG-CZ3 3.95Å; Y110-W126 HydrophobicContact CG-CZ3 3.95Å
111	D	91	Very high	94.1	Very high	25 Å²	25	57.3 Å²	57.3	13%	0.134	29%	0.287	C	S	.	.	H	α-helix	trans	-67.2	-35.5	-179.4	-83.7	17.2	0	0	0	112.6	F57 A107 Q114 S416 W420	F57-D111 HydrophobicContact CE2-CB 3.84Å; F57-D111 HydrophobicContact CZ-CB 4.04Å; A107-D111 PolarHBondContact O-N 3.19Å; D111-Q114 PolarHBondContact O-NE2 2.9Å; D111-S416 PolarHBondContact OD2-OG 3.22Å; D111-W420 PolarHBondContact OD2-NE1 3.41Å
112	V	90.9	Very high	94	Very high	64 Å²	64	56.5 Å²	56.5	39%	0.388	28%	0.281	S	S	.	.	H	α-helix	trans	-72.6	-39.6	177.4	171.8	0	0	0	0	111.8	I54 F57 A108 Y110	I54-V112 HydrophobicContact CD1-CG1 4.06Å; I54-V112 HydrophobicContact CG1-CG1 4.11Å; I54-V112 HydrophobicContact CG1-CG2 3.73Å; F57-V112 HydrophobicContact CD2-CG2 3.98Å; F57-V112 HydrophobicContact CE2-CG2 4.02Å; A108-V112 VanDerWaalsContact O-CB 3.29Å; A108-V112 WeakPolarHBondContact O-CB 3.38Å; A108-V112 WeakPolarHBondContact O-CG2 3.43Å; A108-V112 PolarHBondContact O-N 2.9Å; Y110-V112 PolarHBondContact O-N 2.78Å
113	N	89.8	Confident	93.9	Very high	78 Å²	78	53 Å²	53	42%	0.417	26%	0.263	S	S	.	.	H	α-helix	trans	-85.3	-13.9	-179.4	-69.1	-78	0	0	0	113.7	Y109 Y110 K115	Y109-N113 WeakPolarHBondContact CD2-ND2 3.4Å; Y109-N113 HydrophobicContact CE1-CB 4.48Å; Y109-N113 WeakPolarHBondContact CE2-ND2 3.5Å; Y109-N113 WeakPolarHBondContact O-CB 3.49Å; Y109-N113 PolarHBondContact O-N 3.37Å; Y109-N113 PolarHBondContact O-ND2 2.92Å; Y110-N113 PolarHBondContact O-N 3.11Å; N113-K115 PolarHBondContact O-N 3.19Å
114	Q	87.6	Confident	93.7	Very high	142 Å²	142	54.6 Å²	54.6	66%	0.664	27%	0.27	S	S	*	.	S	Bend	trans	56.7	8.7	-173.1	-61.6	-74.9	-60	0	0	114.4	Y110 D111	Y110-Q114 WeakPolarHBondContact O-CA 3.42Å; Y110-Q114 PolarHBondContact O-N 3.36Å; D111-Q114 PolarHBondContact O-NE2 2.9Å
115	K	88.7	Confident	93.6	Very high	131 Å²	131	57.3 Å²	57.3	57%	0.57	29%	0.287	S	S	*	.	S	Bend	trans	-151.5	136.1	-175.4	-66.1	-175.2	-177.1	177.1	0	109.8	N113 T117 K201	N113-K115 PolarHBondContact O-N 3.19Å; K115-T117 HydrophobicContact CB-CG2 4.44Å; K115-T117 PolarHBondContact O-N 3.01Å; K115-K201 HydrophobicContact CB-CB 4.02Å; K115-K201 HydrophobicContact CG-CB 4.48Å
116	W	92.8	Very high	93.5	Very high	1 Å²	1	55.7 Å²	55.7	0%	0.004	27%	0.274	C	S	.	.			trans	-86.9	100.1	174.8	-172.3	-91.3	0	0	0	111.2	L106 Y110 I118 G119 M122 C123 W126 K201 C203	L106-W116 HydrophobicContact CB-CH2 4.17Å; L106-W116 HydrophobicContact CB-CZ3 4.42Å; L106-W116 HydrophobicContact CD2-CH2 4.25Å; Y110-W116 HydrophobicContact CD2-CB 3.77Å; Y110-W116 AromaticContact CD2-CE3 3.89Å; Y110-W116 HydrophobicContact CD2-CE3 3.89Å; Y110-W116 HydrophobicContact CE2-CB 3.77Å; Y110-W116 HydrophobicContact CG-CE3 4.15Å; W116-I118 HydrophobicContact CH2-CD1 3.79Å; W116-I118 HydrophobicContact CH2-CG1 4.32Å; W116-I118 HydrophobicContact CZ2-CB 3.96Å; W116-I118 HydrophobicContact CZ2-CD1 3.92Å; W116-I118 HydrophobicContact CZ2-CG1 4.03Å; W116-I118 HydrophobicContact CZ3-CD1 4.25Å; W116-G119 PolarHBondContact NE1-O 3.15Å; W116-M122 VanDerWaalsContact CZ2-C 3.41Å; W116-M122 HydrophobicContact CZ2-CB 3.67Å; W116-C123 HydrophobicContact CZ2-CB 4.24Å; W116-W126 AromaticContact CE3-CE3 3.81Å; W116-W126 HydrophobicContact CE3-CE3 3.81Å; W116-W126 AromaticContact CE3-CZ3 3.82Å; W116-W126 HydrophobicContact CE3-CZ3 3.82Å; W116-W126 HydrophobicContact CH2-CB 4.31Å; W116-W126 HydrophobicContact CH2-CD2 4.38Å; W116-W126 AromaticContact CH2-CE3 3.75Å; W116-W126 HydrophobicContact CH2-CE3 3.75Å; W116-W126 HydrophobicContact CZ3-CD2 4.15Å; W116-W126 AromaticContact CZ3-CE3 3.26Å; W116-W126 HydrophobicContact CZ3-CE3 3.26Å; W116-W126 AromaticContact CZ3-CZ3 3.63Å; W116-W126 HydrophobicContact CZ3-CZ3 3.63Å; W116-K201 PolarHBondContact N-O 3.14Å; W116-K201 WeakPolarHBondContact O-CD 3.45Å; W116-C203 HydrophobicContact CB-CB 3.79Å; W116-C203 HydrophobicContact CD2-CB 3.59Å; W116-C203 HydrophobicContact CE3-CB 3.85Å; W116-C203 HydrophobicContact CG-CB 3.54Å
117	T	94.8	Very high	93.4	Very high	78 Å²	78	55 Å²	55	48%	0.479	27%	0.271	S	S	.	.			trans	-106.9	-6.9	-177.5	47.9	0	0	0	0	114.1	Y109 K115 G119	Y109-T117 PolarHBondContact OH-OG1 3.09Å; K115-T117 HydrophobicContact CB-CG2 4.44Å; K115-T117 PolarHBondContact O-N 3.01Å; T117-G119 PolarHBondContact O-N 3.41Å
118	I	94.3	Very high	93.4	Very high	67 Å²	67	56.6 Å²	56.6	34%	0.344	28%	0.278	S	S	.	.	S	Bend	trans	-72.8	-4.3	178.8	-26.9	-177.9	0	0	0	112.8	L106 Y109 W116 M122	L106-I118 HydrophobicContact CD2-CD1 3.98Å; Y109-I118 HydrophobicContact CD1-CD1 3.6Å; Y109-I118 HydrophobicContact CD1-CG1 3.8Å; Y109-I118 HydrophobicContact CD2-CD1 4.46Å; Y109-I118 HydrophobicContact CE1-CD1 3.8Å; Y109-I118 HydrophobicContact CE1-CG1 3.46Å; Y109-I118 VanDerWaalsContact CE1-CG1 3.46Å; Y109-I118 HydrophobicContact CG-CD1 3.97Å; W116-I118 HydrophobicContact CH2-CD1 3.79Å; W116-I118 HydrophobicContact CH2-CG1 4.32Å; W116-I118 HydrophobicContact CZ2-CB 3.96Å; W116-I118 HydrophobicContact CZ2-CD1 3.92Å; W116-I118 HydrophobicContact CZ2-CG1 4.03Å; W116-I118 HydrophobicContact CZ3-CD1 4.25Å; I118-M122 HydrophobicContact CB-CB 4.01Å; I118-M122 HydrophobicContact CB-CG 4.37Å; I118-M122 HydrophobicContact CG2-CB 3.9Å; I118-M122 HydrophobicContact CG2-CG 3.72Å
119	G	94.5	Very high	93.5	Very high	21 Å²	21	58.7 Å²	58.7	22%	0.216	29%	0.285	C	S	.	.			trans	84.3	171.5	173.8	0	0	0	0	0	115.1	W116 T117 R121 M122 C123	W116-G119 PolarHBondContact NE1-O 3.15Å; T117-G119 PolarHBondContact O-N 3.41Å; G119-R121 PolarHBondContact O-N 3.46Å; G119-M122 PolarHBondContact O-N 2.9Å; G119-C123 PolarHBondContact O-N 3.37Å
120	L	93.5	Very high	93.5	Very high	35 Å²	35	55.5 Å²	55.5	18%	0.183	27%	0.274	C	S	.	.	H	α-helix	trans	-51.4	-51.3	-171.1	-170.6	67.5	0	0	0	114.2	M122 C123 E124 F193 T194 V197	L120-M122 VanDerWaalsContact C-N 3.33Å; L120-M122 PolarHBondContact O-N 3.39Å; L120-C123 WeakPolarHBondContact O-CB 3.37Å; L120-C123 PolarHBondContact O-N 2.96Å; L120-E124 WeakPolarHBondContact O-CG 3.25Å; L120-E124 PolarHBondContact O-N 3.37Å; L120-F193 HydrophobicContact CD1-CD1 3.99Å; L120-F193 HydrophobicContact CD1-CE1 3.68Å; L120-T194 HydrophobicContact CD1-CG2 4.4Å; L120-T194 HydrophobicContact CD2-CG2 4.06Å; L120-V197 HydrophobicContact CD1-CB 3.97Å; L120-V197 HydrophobicContact CD1-CG1 4.18Å; L120-V197 HydrophobicContact CD1-CG2 4.24Å
121	R	94.4	Very high	93.6	Very high	175 Å²	175	55 Å²	55	66%	0.66	27%	0.274	S	S	*	.	H	α-helix	trans	-61.1	-38.7	-174.4	-65.4	-49.7	-167.7	-176.4	0.5	113.3	G119 C123 E124 V125	G119-R121 PolarHBondContact O-N 3.46Å; R121-C123 VanDerWaalsContact C-N 3.33Å; R121-E124 WeakPolarHBondContact CD-OE2 3.43Å; R121-E124 IonicContact CZ-OE2 3.79Å; R121-E124 IonicContact NE-OE2 3.64Å; R121-E124 IonicContact NH1-OE1 2.73Å; R121-E124 IonicContact NH1-OE2 3.83Å; R121-E124 PolarHBondContact NH1-OE2 3.13Å; R121-E124 PolarHBondContact O-N 3.34Å; R121-V125 VanDerWaalsContact O-CG2 3.3Å; R121-V125 WeakPolarHBondContact O-CG2 3.22Å; R121-V125 PolarHBondContact O-N 2.86Å
122	M	95.3	Very high	93.9	Very high	79 Å²	79	54.1 Å²	54.1	39%	0.389	27%	0.27	S	S	.	.	H	α-helix	trans	-73.2	-28.7	178.2	-68.1	-64.7	118.8	0	0	111.8	W116 I118 G119 L120 V125 W126	W116-M122 VanDerWaalsContact CZ2-C 3.41Å; W116-M122 HydrophobicContact CZ2-CB 3.67Å; I118-M122 HydrophobicContact CB-CB 4.01Å; I118-M122 HydrophobicContact CB-CG 4.37Å; I118-M122 HydrophobicContact CG2-CB 3.9Å; I118-M122 HydrophobicContact CG2-CG 3.72Å; G119-M122 PolarHBondContact O-N 2.9Å; L120-M122 VanDerWaalsContact C-N 3.33Å; L120-M122 PolarHBondContact O-N 3.39Å; M122-V125 HydrophobicContact CE-CG2 4.36Å; M122-V125 PolarHBondContact O-N 3.32Å; M122-W126 WeakPolarHBondContact O-CB 3.48Å; M122-W126 PolarHBondContact O-N 2.74Å
123	C	95	Very high	94.3	Very high	0 Å²	0	51.1 Å²	51.1	0%	0	25%	0.251	C	S	.	.	H	α-helix	trans	-67.6	-40.5	171.3	-179.8	0	0	0	0	111.5	W116 G119 L120 R121 W126 N127 V197 C203	W116-C123 HydrophobicContact CZ2-CB 4.24Å; G119-C123 PolarHBondContact O-N 3.37Å; L120-C123 WeakPolarHBondContact O-CB 3.37Å; L120-C123 PolarHBondContact O-N 2.96Å; R121-C123 VanDerWaalsContact C-N 3.33Å; C123-W126 PolarHBondContact O-N 2.99Å; C123-N127 WeakPolarHBondContact O-CB 3.26Å; C123-N127 PolarHBondContact O-N 3.03Å; C123-N127 PolarHBondContact O-ND2 3.02Å; C123-N127 PolarHBondContact SG-ND2 3.03Å; C123-V197 HydrophobicContact CB-CG1 3.96Å; C123-V197 HydrophobicContact CB-CG2 4.24Å; C123-V197 VanDerWaalsContact SG-CG2 3.6Å; C123-C203 WeakPolarHBondContact CA-SG 3.04Å; C123-C203 HydrophobicContact CB-CB 3.88Å; C123-C203 WeakPolarHBondContact CB-SG 3.49Å; C123-C203 VanDerWaalsContact SG-CA 3.52Å; C123-C203 WeakPolarHBondContact SG-CB 3.46Å; C123-C203 CovalentContact SG-SG 2.03Å; C123-C203 PolarHBondContact SG-SG 2.72Å
124	E	94.1	Very high	94.6	Very high	33 Å²	33	47.8 Å²	47.8	15%	0.154	23%	0.234	C	C	.	.	H	α-helix	trans	-62.1	-43.8	173.6	-64	178.8	128.5	0	0	111.7	L120 R121 F128 K189 F193	L120-E124 WeakPolarHBondContact O-CG 3.25Å; L120-E124 PolarHBondContact O-N 3.37Å; R121-E124 WeakPolarHBondContact CD-OE2 3.43Å; R121-E124 IonicContact CZ-OE2 3.79Å; R121-E124 IonicContact NE-OE2 3.64Å; R121-E124 IonicContact NH1-OE1 2.73Å; R121-E124 IonicContact NH1-OE2 3.83Å; R121-E124 PolarHBondContact NH1-OE2 3.13Å; R121-E124 PolarHBondContact O-N 3.34Å; E124-F128 VanDerWaalsContact O-CB 3.29Å; E124-F128 WeakPolarHBondContact O-CB 3.22Å; E124-F128 PolarHBondContact O-N 2.67Å; E124-K189 IonicContact OE1-NZ 2.65Å; E124-K189 PolarHBondContact OE1-NZ 3.27Å; E124-F193 HydrophobicContact CG-CE1 4.18Å; E124-F193 HydrophobicContact CG-CZ 4.43Å
125	V	94.6	Very high	95.1	Very high	56 Å²	56	41.1 Å²	41.1	34%	0.339	20%	0.203	S	C	.	.	H	α-helix	trans	-63.6	-45	176.9	168.5	0	0	0	0	111.8	R121 M122 F128 F129	R121-V125 VanDerWaalsContact O-CG2 3.3Å; R121-V125 WeakPolarHBondContact O-CG2 3.22Å; R121-V125 PolarHBondContact O-N 2.86Å; M122-V125 HydrophobicContact CE-CG2 4.36Å; M122-V125 PolarHBondContact O-N 3.32Å; V125-F128 PolarHBondContact O-N 3.27Å; V125-F129 HydrophobicContact CG1-CD2 3.74Å; V125-F129 HydrophobicContact CG1-CE2 3.92Å; V125-F129 WeakPolarHBondContact O-CD2 3.25Å; V125-F129 PolarHBondContact O-N 3.04Å
126	W	96.2	Very high	95.5	Very high	13 Å²	13	34.9 Å²	34.9	5%	0.049	18%	0.176	C	C	.	.	H	α-helix	trans	-60.7	-54.6	177.5	178.3	22.4	0	0	0	111.4	L106 A107 Y110 W116 M122 C123 F128 F129 D130 C203	L106-W126 HydrophobicContact CB-CB 4.28Å; L106-W126 HydrophobicContact CB-CD2 4.2Å; L106-W126 HydrophobicContact CB-CG 3.91Å; L106-W126 HydrophobicContact CD1-CB 3.76Å; L106-W126 HydrophobicContact CD1-CG 4.24Å; A107-W126 HydrophobicContact CB-CH2 4.42Å; A107-W126 HydrophobicContact CB-CZ2 3.59Å; Y110-W126 AromaticContact CD1-CH2 3.76Å; Y110-W126 HydrophobicContact CD1-CH2 3.76Å; Y110-W126 AromaticContact CD1-CZ3 3.97Å; Y110-W126 HydrophobicContact CD1-CZ3 3.97Å; Y110-W126 HydrophobicContact CG-CH2 4.09Å; Y110-W126 AromaticContact CG-CZ3 3.95Å; Y110-W126 HydrophobicContact CG-CZ3 3.95Å; W116-W126 AromaticContact CE3-CE3 3.81Å; W116-W126 HydrophobicContact CE3-CE3 3.81Å; W116-W126 AromaticContact CE3-CZ3 3.82Å; W116-W126 HydrophobicContact CE3-CZ3 3.82Å; W116-W126 HydrophobicContact CH2-CB 4.31Å; W116-W126 HydrophobicContact CH2-CD2 4.38Å; W116-W126 AromaticContact CH2-CE3 3.75Å; W116-W126 HydrophobicContact CH2-CE3 3.75Å; W116-W126 HydrophobicContact CZ3-CD2 4.15Å; W116-W126 AromaticContact CZ3-CE3 3.26Å; W116-W126 HydrophobicContact CZ3-CE3 3.26Å; W116-W126 AromaticContact CZ3-CZ3 3.63Å; W116-W126 HydrophobicContact CZ3-CZ3 3.63Å; M122-W126 WeakPolarHBondContact O-CB 3.48Å; M122-W126 PolarHBondContact O-N 2.74Å; C123-W126 PolarHBondContact O-N 2.99Å; W126-F128 VanDerWaalsContact C-N 3.28Å; W126-F128 PolarHBondContact O-N 3.13Å; W126-F129 PolarHBondContact O-N 2.94Å; W126-D130 WeakPolarHBondContact O-CB 3.25Å; W126-D130 PolarHBondContact O-N 3.08Å; W126-C203 HydrophobicContact CE3-CB 4.22Å; W126-C203 VanDerWaalsContact CE3-SG 3.55Å; W126-C203 HydrophobicContact CZ3-CB 4.01Å
127	N	94.1	Very high	95.8	Very high	22 Å²	22	34.9 Å²	34.9	12%	0.118	18%	0.176	C	C	.	.	H	α-helix	trans	-57.7	-40.6	179	-76	-63.1	0	0	0	111.9	C123 V131 C203 M205	C123-N127 WeakPolarHBondContact O-CB 3.26Å; C123-N127 PolarHBondContact O-N 3.03Å; C123-N127 PolarHBondContact O-ND2 3.02Å; C123-N127 PolarHBondContact SG-ND2 3.03Å; N127-V131 WeakPolarHBondContact O-CG2 3.5Å; N127-V131 PolarHBondContact O-N 3.49Å; N127-C203 PolarHBondContact ND2-SG 3.36Å; N127-M205 PolarHBondContact OD1-N 3.1Å
128	F	95.6	Very high	96	Very high	35 Å²	35	31.2 Å²	31.2	15%	0.154	15%	0.153	C	C	.	.	H	α-helix	trans	-61.8	-50.8	176.8	170.9	-103.8	0	0	0	112.4	E124 V125 W126 L132 L178 V182 I185	E124-F128 VanDerWaalsContact O-CB 3.29Å; E124-F128 WeakPolarHBondContact O-CB 3.22Å; E124-F128 PolarHBondContact O-N 2.67Å; V125-F128 PolarHBondContact O-N 3.27Å; W126-F128 VanDerWaalsContact C-N 3.28Å; W126-F128 PolarHBondContact O-N 3.13Å; F128-L132 HydrophobicContact CE1-CD2 3.93Å; F128-L132 HydrophobicContact CZ-CD2 3.86Å; F128-L132 WeakPolarHBondContact O-CB 3.32Å; F128-L132 PolarHBondContact O-N 3.15Å; F128-L178 HydrophobicContact CZ-CD2 4.01Å; F128-V182 HydrophobicContact CE2-CG2 3.79Å; F128-I185 HydrophobicContact CB-CD1 4.22Å; F128-I185 HydrophobicContact CD2-CD1 3.53Å; F128-I185 HydrophobicContact CD2-CG1 4.49Å; F128-I185 HydrophobicContact CE2-CD1 4.03Å; F128-I185 HydrophobicContact CG-CD1 3.88Å
129	F	97.1	Very high	96.2	Very high	55 Å²	55	29.1 Å²	29.1	24%	0.241	14%	0.143	C	C	.	.	H	α-helix	trans	-71	-31.2	-177.5	-82	-63.4	0	0	0	113.3	M98 L102 V103 V125 W126 L132 A133	M98-F129 HydrophobicContact CE-CD1 4.24Å; M98-F129 HydrophobicContact CG-CD1 4.04Å; M98-F129 HydrophobicContact SD-CD1 3.58Å; M98-F129 VanDerWaalsContact SD-CD1 3.58Å; M98-F129 HydrophobicContact SD-CE1 3.9Å; L102-F129 HydrophobicContact CB-CB 4.48Å; L102-F129 HydrophobicContact CB-CG 4.45Å; L102-F129 HydrophobicContact CD1-CD1 3.77Å; L102-F129 HydrophobicContact CD1-CD2 3.92Å; L102-F129 HydrophobicContact CD1-CE1 3.72Å; L102-F129 HydrophobicContact CD1-CE2 3.87Å; L102-F129 HydrophobicContact CD1-CG 3.88Å; L102-F129 HydrophobicContact CD1-CZ 3.78Å; V103-F129 HydrophobicContact CG2-CB 4.01Å; V125-F129 HydrophobicContact CG1-CD2 3.74Å; V125-F129 HydrophobicContact CG1-CE2 3.92Å; V125-F129 WeakPolarHBondContact O-CD2 3.25Å; V125-F129 PolarHBondContact O-N 3.04Å; W126-F129 PolarHBondContact O-N 2.94Å; F129-L132 HydrophobicContact CD1-CD2 4.24Å; F129-L132 HydrophobicContact CE1-CD2 4.4Å; F129-A133 WeakPolarHBondContact O-CB 3.45Å; F129-A133 PolarHBondContact O-N 3.11Å
130	D	96.3	Very high	96.3	Very high	20 Å²	20	28.1 Å²	28.1	11%	0.107	13%	0.133	C	C	.	.	H	α-helix	trans	-63.7	-53.4	175	-165.4	3.6	0	0	0	111.2	V103 W126 L132 A133 C134 Y423	V103-D130 HydrophobicContact CG1-CB 3.7Å; V103-D130 HydrophobicContact CG2-CB 4.41Å; W126-D130 WeakPolarHBondContact O-CB 3.25Å; W126-D130 PolarHBondContact O-N 3.08Å; D130-L132 VanDerWaalsContact C-N 3.31Å; D130-L132 PolarHBondContact O-N 2.93Å; D130-A133 PolarHBondContact O-N 3.38Å; D130-C134 WeakPolarHBondContact O-CB 3.36Å; D130-C134 PolarHBondContact O-N 3.08Å; D130-Y423 WeakPolarHBondContact OD1-CE1 3.31Å; D130-Y423 PolarHBondContact OD2-OH 2.92Å
131	V	95.3	Very high	96.5	Very high	24 Å²	24	26.6 Å²	26.6	15%	0.145	13%	0.125	C	C	.	.	H	α-helix	trans	-61.1	-42.2	177.2	-178.2	0	0	0	0	110.8	N127 T135 I180 M205	N127-V131 WeakPolarHBondContact O-CG2 3.5Å; N127-V131 PolarHBondContact O-N 3.49Å; V131-T135 WeakPolarHBondContact O-CB 3.39Å; V131-T135 PolarHBondContact O-N 3.49Å; V131-T135 PolarHBondContact O-OG1 2.9Å; V131-I180 HydrophobicContact CG1-CG2 4.49Å; V131-M205 HydrophobicContact CG2-CE 3.44Å; V131-M205 VanDerWaalsContact CG2-CE 3.44Å
132	L	97.5	Very high	96.7	Very high	8 Å²	8	18.9 Å²	18.9	4%	0.042	10%	0.097	C	C	.	.	H	α-helix	trans	-62.8	-45.7	178.8	-178	63.5	0	0	0	111.6	M98 F128 F129 D130 A136 W174 A177 L178 S181	M98-L132 HydrophobicContact CE-CB 4.13Å; M98-L132 HydrophobicContact CE-CD2 3.95Å; M98-L132 HydrophobicContact CE-CG 3.82Å; M98-L132 HydrophobicContact SD-CD2 4.28Å; F128-L132 HydrophobicContact CE1-CD2 3.93Å; F128-L132 HydrophobicContact CZ-CD2 3.86Å; F128-L132 WeakPolarHBondContact O-CB 3.32Å; F128-L132 PolarHBondContact O-N 3.15Å; F129-L132 HydrophobicContact CD1-CD2 4.24Å; F129-L132 HydrophobicContact CE1-CD2 4.4Å; D130-L132 VanDerWaalsContact C-N 3.31Å; D130-L132 PolarHBondContact O-N 2.93Å; L132-A136 WeakPolarHBondContact O-CB 3.35Å; L132-A136 PolarHBondContact O-N 3.47Å; L132-W174 HydrophobicContact CD1-CE3 4.42Å; L132-W174 HydrophobicContact CD1-CZ3 4.42Å; L132-W174 HydrophobicContact CD2-CZ3 4.48Å; L132-W174 HydrophobicContact CG-CZ3 4.23Å; L132-A177 HydrophobicContact CD1-CB 3.87Å; L132-L178 HydrophobicContact CD1-CB 4.47Å; L132-L178 HydrophobicContact CD1-CD2 3.71Å; L132-L178 HydrophobicContact CD1-CG 3.87Å; L132-L178 HydrophobicContact CD2-CD2 3.94Å; L132-S181 WeakPolarHBondContact CA-OG 3.42Å; L132-S181 PolarHBondContact N-OG 3Å
133	A	97.8	Very high	96.9	Very high	0 Å²	0	15.4 Å²	15.4	0%	0	8%	0.081	C	C	.	.	H	α-helix	trans	-65.9	-50.2	179.6	0	0	0	0	0	111.6	M98 V99 F129 D130 A136 S137	M98-A133 VanDerWaalsContact CE-CA 3.46Å; M98-A133 HydrophobicContact CE-CB 3.51Å; V99-A133 HydrophobicContact CG2-CB 3.51Å; F129-A133 WeakPolarHBondContact O-CB 3.45Å; F129-A133 PolarHBondContact O-N 3.11Å; D130-A133 PolarHBondContact O-N 3.38Å; A133-A136 PolarHBondContact O-N 3.42Å; A133-S137 WeakPolarHBondContact O-CB 3.38Å; A133-S137 PolarHBondContact O-N 2.93Å; A133-S137 PolarHBondContact O-OG 3.21Å
134	C	96.9	Very high	96.9	Very high	8 Å²	8	15.7 Å²	15.7	5%	0.054	8%	0.082	C	C	.	.	H	α-helix	trans	-62.9	-46.2	-178.7	-172.9	0	0	0	0	111.8	D130 S137 I138 W380	D130-C134 WeakPolarHBondContact O-CB 3.36Å; D130-C134 PolarHBondContact O-N 3.08Å; C134-S137 PolarHBondContact O-N 3.46Å; C134-I138 PolarHBondContact O-N 2.89Å; C134-I138 VanDerWaalsContact O-N 3.09Å; C134-W380 HydrophobicContact CB-CH2 3.96Å; C134-W380 HydrophobicContact CB-CZ2 4.09Å; C134-W380 HydrophobicContact CB-CZ3 4.37Å
135	T	97.7	Very high	97	Very high	2 Å²	2	14.1 Å²	14.1	1%	0.012	8%	0.075	C	C	.	.	H	α-helix	trans	-64.6	-43.3	177.2	-52.8	0	0	0	0	111.3	V131 S137 I138 L139 A177 I180	V131-T135 WeakPolarHBondContact O-CB 3.39Å; V131-T135 PolarHBondContact O-N 3.49Å; V131-T135 PolarHBondContact O-OG1 2.9Å; T135-S137 PolarHBondContact O-N 3.24Å; T135-I138 WeakPolarHBondContact O-CG2 3.34Å; T135-L139 HydrophobicContact CG2-CD1 3.8Å; T135-L139 HydrophobicContact CG2-CG 4.38Å; T135-L139 VanDerWaalsContact O-CB 3.3Å; T135-L139 WeakPolarHBondContact O-CB 3.47Å; T135-L139 VanDerWaalsContact O-CG 3.23Å; T135-L139 WeakPolarHBondContact O-CG 3.49Å; T135-L139 PolarHBondContact O-N 3.07Å; T135-A177 HydrophobicContact CG2-CB 4.02Å; T135-I180 HydrophobicContact CG2-CB 4.3Å; T135-I180 HydrophobicContact CG2-CD1 3.87Å; T135-I180 HydrophobicContact CG2-CG2 4.28Å
136	A	98.5	Very high	97	Very high	0 Å²	0	14 Å²	14	0%	0	7%	0.072	C	C	.	.	H	α-helix	trans	-61.5	-43.6	174.7	0	0	0	0	0	111.4	A95 L132 A133 L139 H140 W174 A177	A95-A136 HydrophobicContact CB-CB 4.09Å; L132-A136 WeakPolarHBondContact O-CB 3.35Å; L132-A136 PolarHBondContact O-N 3.47Å; A133-A136 PolarHBondContact O-N 3.42Å; A136-L139 PolarHBondContact O-N 3.23Å; A136-H140 WeakPolarHBondContact O-CB 3.42Å; A136-H140 PolarHBondContact O-N 2.96Å; A136-H140 PolarHBondContact O-ND1 3.32Å; A136-W174 HydrophobicContact CB-CE3 4.11Å; A136-W174 HydrophobicContact CB-CH2 4.06Å; A136-W174 HydrophobicContact CB-CZ3 3.84Å; A136-A177 HydrophobicContact CB-CB 3.98Å
137	S	98.3	Very high	96.9	Very high	2 Å²	2	13.4 Å²	13.4	1%	0.014	7%	0.07	C	C	.	.	H	α-helix	trans	-63.6	-47.3	-178.8	-75.4	0	0	0	0	112.4	A95 D96 A133 C134 T135 L139 H140 L141	A95-S137 WeakPolarHBondContact CB-OG 3.42Å; D96-S137 PolarHBondContact OD1-OG 3.21Å; A133-S137 WeakPolarHBondContact O-CB 3.38Å; A133-S137 PolarHBondContact O-N 2.93Å; A133-S137 PolarHBondContact O-OG 3.21Å; C134-S137 PolarHBondContact O-N 3.46Å; T135-S137 PolarHBondContact O-N 3.24Å; S137-L139 PolarHBondContact O-N 3.08Å; S137-H140 PolarHBondContact O-N 2.96Å; S137-L141 WeakPolarHBondContact O-CG 3.45Å; S137-L141 PolarHBondContact O-N 2.84Å
138	I	98.1	Very high	96.8	Very high	0 Å²	0	12.8 Å²	12.8	0%	0	7%	0.066	C	C	.	.	H	α-helix	trans	-67.5	-36.9	177.1	-165.4	169.4	0	0	0	112.6	C134 T135 H140 L141 V142 A219 F220 P223 L224 I227 F376	C134-I138 PolarHBondContact O-N 2.89Å; C134-I138 VanDerWaalsContact O-N 3.09Å; T135-I138 WeakPolarHBondContact O-CG2 3.34Å; I138-H140 PolarHBondContact O-N 2.79Å; I138-L141 WeakPolarHBondContact O-CA 3.33Å; I138-L141 WeakPolarHBondContact O-CB 3.38Å; I138-L141 PolarHBondContact O-N 3.37Å; I138-L141 VanDerWaalsContact O-N 3.1Å; I138-V142 PolarHBondContact O-N 3.4Å; I138-A219 VanDerWaalsContact CG2-O 3.25Å; I138-A219 WeakPolarHBondContact CG2-O 3.47Å; I138-F220 HydrophobicContact CD1-CD2 3.77Å; I138-F220 HydrophobicContact CD1-CE2 4.13Å; I138-F220 HydrophobicContact CD1-CG 4.49Å; I138-P223 HydrophobicContact CB-CB 4.39Å; I138-P223 HydrophobicContact CD1-CB 3.77Å; I138-P223 HydrophobicContact CG1-CB 3.73Å; I138-P223 HydrophobicContact CG2-CB 3.87Å; I138-P223 HydrophobicContact CG2-CG 4.19Å; I138-L224 HydrophobicContact CD1-CB 4.34Å; I138-I227 HydrophobicContact CD1-CD1 4.21Å; I138-I227 HydrophobicContact CG1-CD1 3.58Å; I138-F376 HydrophobicContact CB-CD1 4.45Å; I138-F376 HydrophobicContact CB-CE1 3.68Å; I138-F376 HydrophobicContact CB-CE2 4.45Å; I138-F376 HydrophobicContact CB-CZ 3.68Å; I138-F376 HydrophobicContact CD1-CD1 4.35Å; I138-F376 HydrophobicContact CD1-CE1 3.79Å; I138-F376 HydrophobicContact CG1-CD1 4.35Å; I138-F376 HydrophobicContact CG1-CE1 3.89Å; I138-F376 HydrophobicContact CG1-CZ 4.41Å
139	L	98.4	Very high	96.6	Very high	23 Å²	23	14.1 Å²	14.1	12%	0.12	7%	0.07	C	C	.	.	H	α-helix	trans	-68	-33.1	174.9	-71.5	175.6	0	0	0	112.4	T135 A136 S137 L141 V142 A143 V173 V176 A177 P223	T135-L139 HydrophobicContact CG2-CD1 3.8Å; T135-L139 HydrophobicContact CG2-CG 4.38Å; T135-L139 VanDerWaalsContact O-CB 3.3Å; T135-L139 WeakPolarHBondContact O-CB 3.47Å; T135-L139 VanDerWaalsContact O-CG 3.23Å; T135-L139 WeakPolarHBondContact O-CG 3.49Å; T135-L139 PolarHBondContact O-N 3.07Å; A136-L139 PolarHBondContact O-N 3.23Å; S137-L139 PolarHBondContact O-N 3.08Å; L139-L141 VanDerWaalsContact C-N 3.32Å; L139-V142 WeakPolarHBondContact O-CB 3.34Å; L139-V142 PolarHBondContact O-N 2.91Å; L139-A143 WeakPolarHBondContact O-CB 3.46Å; L139-A143 PolarHBondContact O-N 2.8Å; L139-V173 HydrophobicContact CB-CB 4.34Å; L139-V173 HydrophobicContact CB-CG1 3.65Å; L139-V173 HydrophobicContact CB-CG2 4.13Å; L139-V176 HydrophobicContact CD1-CB 3.98Å; L139-V176 HydrophobicContact CD1-CG1 3.7Å; L139-A177 HydrophobicContact CD1-CB 4.27Å; L139-P223 HydrophobicContact CD2-CB 4.28Å; L139-P223 HydrophobicContact CD2-CG 3.85Å; L139-P223 HydrophobicContact CG-CG 4.49Å
140	H	98.5	Very high	96.4	Very high	0 Å²	0	15.1 Å²	15.1	0%	0	7%	0.072	C	C	.	.	H	α-helix	trans	-64	-37.2	168.4	-78.8	102.9	0	0	0	111.5	S91 L92 A136 S137 I138 A143 I144 V173 W174	S91-H140 VanDerWaalsContact CB-NE2 3.28Å; S91-H140 WeakPolarHBondContact CB-NE2 3.37Å; S91-H140 PolarHBondContact OG-CE1 3.25Å; S91-H140 PolarHBondContact OG-NE2 3.34Å; L92-H140 HydrophobicContact CB-CB 4.03Å; L92-H140 HydrophobicContact CD1-CB 4.1Å; A136-H140 WeakPolarHBondContact O-CB 3.42Å; A136-H140 PolarHBondContact O-N 2.96Å; A136-H140 PolarHBondContact O-ND1 3.32Å; S137-H140 PolarHBondContact O-N 2.96Å; I138-H140 PolarHBondContact O-N 2.79Å; H140-A143 PolarHBondContact O-N 2.62Å; H140-I144 WeakPolarHBondContact O-CB 3.5Å; H140-I144 WeakPolarHBondContact O-CG1 3.4Å; H140-I144 PolarHBondContact O-N 3.36Å; H140-V173 WeakPolarHBondContact CE1-CG1 3.42Å; H140-V173 WeakPolarHBondContact ND1-CG1 3.03Å; H140-W174 AromaticContact CE1-CE2 3.81Å; H140-W174 AromaticContact CE1-NE1 3.55Å; H140-W174 AromaticContact NE2-NE1 3.77Å
141	L	97.7	Very high	96.1	Very high	4 Å²	4	14.2 Å²	14.2	2%	0.021	7%	0.068	C	C	.	.	H	α-helix	trans	-65.3	-39.2	173.1	-63.8	174.2	0	0	0	112.2	L92 S137 I138 L139 I144 A145 I227 V372 F376	L92-L141 HydrophobicContact CD2-CD2 3.99Å; S137-L141 WeakPolarHBondContact O-CG 3.45Å; S137-L141 PolarHBondContact O-N 2.84Å; I138-L141 WeakPolarHBondContact O-CA 3.33Å; I138-L141 WeakPolarHBondContact O-CB 3.38Å; I138-L141 PolarHBondContact O-N 3.37Å; I138-L141 VanDerWaalsContact O-N 3.1Å; L139-L141 VanDerWaalsContact C-N 3.32Å; L141-I144 PolarHBondContact O-N 3.48Å; L141-A145 VanDerWaalsContact O-CB 3.31Å; L141-A145 WeakPolarHBondContact O-CB 3.44Å; L141-A145 PolarHBondContact O-N 3.49Å; L141-I227 HydrophobicContact CB-CD1 3.77Å; L141-V372 HydrophobicContact CD2-CG1 3.85Å; L141-F376 HydrophobicContact CD1-CB 3.5Å; L141-F376 VanDerWaalsContact CD1-CB 3.5Å; L141-F376 HydrophobicContact CD1-CD1 4.11Å; L141-F376 HydrophobicContact CD1-CD2 3.78Å; L141-F376 HydrophobicContact CD1-CG 3.5Å; L141-F376 VanDerWaalsContact CD1-CG 3.5Å
142	V	98.3	Very high	95.7	Very high	13 Å²	13	13.4 Å²	13.4	8%	0.079	6%	0.063	C	C	.	.	H	α-helix	trans	-58.1	-48.9	169.6	176.8	0	0	0	0	110.5	I138 L139 I144 A145 L146 P223 L226 I227 L230	I138-V142 PolarHBondContact O-N 3.4Å; L139-V142 WeakPolarHBondContact O-CB 3.34Å; L139-V142 PolarHBondContact O-N 2.91Å; V142-I144 PolarHBondContact O-N 2.75Å; V142-A145 PolarHBondContact O-N 3.33Å; V142-L146 HydrophobicContact CG1-CD1 4.05Å; V142-L146 WeakPolarHBondContact O-CG 3.35Å; V142-L146 PolarHBondContact O-N 3.27Å; V142-P223 HydrophobicContact CG2-CB 3.94Å; V142-L226 HydrophobicContact CG1-CB 4.4Å; V142-L226 HydrophobicContact CG2-CB 4.39Å; V142-I227 HydrophobicContact CB-CG1 4.46Å; V142-I227 HydrophobicContact CG2-CD1 4.02Å; V142-I227 HydrophobicContact CG2-CG1 3.7Å; V142-L230 HydrophobicContact CG1-CD1 4.17Å
143	A	97.8	Very high	95.2	Very high	5 Å²	5	14 Å²	14	4%	0.041	7%	0.069	C	C	.	.	H	α-helix	trans	-63.2	-40.5	-179	0	0	0	0	0	112.5	L88 L139 H140 L146 D147 M169 V173	L88-A143 HydrophobicContact CD2-CB 4.1Å; L139-A143 WeakPolarHBondContact O-CB 3.46Å; L139-A143 PolarHBondContact O-N 2.8Å; H140-A143 PolarHBondContact O-N 2.62Å; A143-L146 PolarHBondContact O-N 3.02Å; A143-D147 PolarHBondContact O-N 3.16Å; A143-M169 HydrophobicContact CB-CE 3.97Å; A143-M169 WeakPolarHBondContact O-CE 3.37Å; A143-V173 HydrophobicContact CB-CG2 3.92Å
144	I	96.2	Very high	94.7	Very high	6 Å²	6	19.3 Å²	19.3	3%	0.031	9%	0.093	C	C	.	.	H	α-helix	trans	-63.2	-44.9	172.8	-73.2	167.8	0	0	0	110.5	L88 I89 L92 H140 L141 V142 L146 D147 R148 L369	L88-I144 HydrophobicContact CB-CD1 4.31Å; L88-I144 HydrophobicContact CB-CG1 3.7Å; L88-I144 HydrophobicContact CD1-CG1 4.13Å; I89-I144 HydrophobicContact CG1-CD1 4.15Å; L92-I144 HydrophobicContact CD2-CD1 4.21Å; H140-I144 WeakPolarHBondContact O-CB 3.5Å; H140-I144 WeakPolarHBondContact O-CG1 3.4Å; H140-I144 PolarHBondContact O-N 3.36Å; L141-I144 PolarHBondContact O-N 3.48Å; V142-I144 PolarHBondContact O-N 2.75Å; I144-L146 PolarHBondContact O-N 2.66Å; I144-D147 PolarHBondContact O-N 3.34Å; I144-R148 WeakPolarHBondContact O-CB 3.2Å; I144-R148 WeakPolarHBondContact O-CG 3.46Å; I144-R148 PolarHBondContact O-N 3.02Å; I144-L369 HydrophobicContact CG2-CB 4.28Å; I144-L369 HydrophobicContact CG2-CD1 3.76Å; I144-L369 HydrophobicContact CG2-CD2 3.87Å; I144-L369 HydrophobicContact CG2-CG 4.15Å
145	A	95.9	Very high	93.9	Very high	0 Å²	0	21.7 Å²	21.7	0%	0	11%	0.105	C	C	.	.	H	α-helix	trans	-64.1	-37.3	177.5	0	0	0	0	0	112.1	L141 V142 R148 Y149 L230 Y231	L141-A145 VanDerWaalsContact O-CB 3.31Å; L141-A145 WeakPolarHBondContact O-CB 3.44Å; L141-A145 PolarHBondContact O-N 3.49Å; V142-A145 PolarHBondContact O-N 3.33Å; A145-R148 PolarHBondContact O-N 3.44Å; A145-Y149 WeakPolarHBondContact O-CB 3.32Å; A145-Y149 PolarHBondContact O-N 2.86Å; A145-L230 HydrophobicContact CB-CB 3.96Å; A145-L230 HydrophobicContact CB-CD1 3.9Å; A145-Y231 HydrophobicContact CB-CD2 4.46Å; A145-Y231 HydrophobicContact CB-CE2 4.03Å
146	L	95.7	Very high	93.4	Very high	53 Å²	53	24.2 Å²	24.2	28%	0.277	13%	0.126	S	C	.	.	H	α-helix	trans	-63.3	-48.8	172.3	-77.4	166	0	0	0	112.4	V142 A143 I144 R148 Y149 W150 M169 L230	V142-L146 HydrophobicContact CG1-CD1 4.05Å; V142-L146 WeakPolarHBondContact O-CG 3.35Å; V142-L146 PolarHBondContact O-N 3.27Å; A143-L146 PolarHBondContact O-N 3.02Å; I144-L146 PolarHBondContact O-N 2.66Å; L146-R148 VanDerWaalsContact C-N 3.27Å; L146-R148 PolarHBondContact O-N 3.48Å; L146-Y149 PolarHBondContact O-N 3.49Å; L146-W150 HydrophobicContact CB-CZ3 4.47Å; L146-W150 HydrophobicContact CD2-CZ2 4.48Å; L146-W150 PolarHBondContact O-N 3.14Å; L146-M169 HydrophobicContact CB-CE 4.31Å; L146-L230 HydrophobicContact CD2-CD1 4.04Å; L146-L230 HydrophobicContact CD2-CD2 3.61Å; L146-L230 HydrophobicContact CD2-CG 4.49Å; L146-L230 HydrophobicContact CG-CD1 3.79Å; L146-L230 HydrophobicContact CG-CD2 4.2Å
147	D	94	Very high	92.9	Very high	2 Å²	2	25.2 Å²	25.2	1%	0.011	13%	0.13	C	C	.	.	H	α-helix	trans	-57.8	-41.1	174.8	171.9	88.8	0	0	0	111.5	L88 A143 I144 S151 Y157 R161 M169	L88-D147 HydrophobicContact CD1-CB 4Å; A143-D147 PolarHBondContact O-N 3.16Å; I144-D147 PolarHBondContact O-N 3.34Å; D147-S151 WeakPolarHBondContact O-CB 3.36Å; D147-S151 PolarHBondContact O-N 3Å; D147-S151 PolarHBondContact O-OG 3.09Å; D147-Y157 PolarHBondContact OD1-OH 2.89Å; D147-Y157 VanDerWaalsContact OD1-OH 3.1Å; D147-R161 WeakPolarHBondContact OD1-CD 3.33Å; D147-R161 IonicContact OD1-CZ 3.56Å; D147-R161 VanDerWaalsContact OD1-CZ 3.25Å; D147-R161 IonicContact OD1-NE 3.83Å; D147-R161 IonicContact OD1-NH1 3.27Å; D147-R161 PolarHBondContact OD1-NH1 2.83Å; D147-R161 IonicContact OD2-CZ 2.7Å; D147-R161 IonicContact OD2-NH1 3.35Å; D147-R161 PolarHBondContact OD2-NH1 3.32Å; D147-M169 HydrophobicContact CB-CE 4.42Å
148	R	91.5	Very high	92.2	Very high	8 Å²	8	27.7 Å²	27.7	3%	0.03	14%	0.143	C	C	.	.	H	α-helix	trans	-66.6	-45	174.4	-72.8	-53.5	94.1	174.6	12.8	112.7	I144 A145 L146 S151 V152 I234 E362 L369	I144-R148 WeakPolarHBondContact O-CB 3.2Å; I144-R148 WeakPolarHBondContact O-CG 3.46Å; I144-R148 PolarHBondContact O-N 3.02Å; A145-R148 PolarHBondContact O-N 3.44Å; L146-R148 VanDerWaalsContact C-N 3.27Å; L146-R148 PolarHBondContact O-N 3.48Å; R148-S151 WeakPolarHBondContact O-CB 3.27Å; R148-S151 PolarHBondContact O-N 2.94Å; R148-V152 WeakPolarHBondContact O-CB 3.16Å; R148-V152 WeakPolarHBondContact O-CG2 3.35Å; R148-V152 PolarHBondContact O-N 3.49Å; R148-I234 HydrophobicContact CB-CD1 3.9Å; R148-E362 IonicContact CZ-OE2 2.66Å; R148-E362 IonicContact NH1-OE2 2.83Å; R148-E362 PolarHBondContact NH1-OE2 2.91Å; R148-L369 HydrophobicContact CG-CD1 3.6Å
149	Y	92.1	Very high	91.3	Very high	63 Å²	63	35 Å²	35	25%	0.247	18%	0.177	C	C	.	.	H	α-helix	trans	-57.8	-50.7	177.2	172.7	-112.8	0	0	0	111.2	A145 L146 S151 V152 A153 L230 R233 I234 V237	A145-Y149 WeakPolarHBondContact O-CB 3.32Å; A145-Y149 PolarHBondContact O-N 2.86Å; L146-Y149 PolarHBondContact O-N 3.49Å; Y149-S151 VanDerWaalsContact C-N 3.32Å; Y149-S151 PolarHBondContact O-N 3.31Å; Y149-V152 PolarHBondContact O-N 2.87Å; Y149-A153 HydrophobicContact CE2-CB 4.19Å; Y149-A153 WeakPolarHBondContact O-CB 3.35Å; Y149-A153 PolarHBondContact O-N 3.49Å; Y149-L230 HydrophobicContact CG-CD2 4.43Å; Y149-R233 HydrophobicContact CD2-CB 3.93Å; Y149-R233 HydrophobicContact CE2-CB 3.72Å; Y149-I234 HydrophobicContact CD2-CG1 4.26Å; Y149-V237 HydrophobicContact CE2-CG2 4.29Å
150	W	92.3	Very high	90.5	Very high	76 Å²	76	40.6 Å²	40.6	29%	0.288	20%	0.202	S	C	.	.	H	α-helix	trans	-63.8	-35.9	177.7	-66.2	-35.7	0	0	0	113	L146 H154 Y157 M169	L146-W150 HydrophobicContact CB-CZ3 4.47Å; L146-W150 HydrophobicContact CD2-CZ2 4.48Å; L146-W150 PolarHBondContact O-N 3.14Å; W150-H154 PolarHBondContact O-N 3.18Å; W150-Y157 HydrophobicContact CB-CD1 3.65Å; W150-Y157 HydrophobicContact CB-CD2 3.9Å; W150-Y157 HydrophobicContact CB-CE1 3.78Å; W150-Y157 HydrophobicContact CB-CE2 4.03Å; W150-Y157 HydrophobicContact CB-CG 3.71Å; W150-Y157 HydrophobicContact CD2-CE2 4.41Å; W150-Y157 AromaticContact CE3-CE2 3.88Å; W150-Y157 HydrophobicContact CE3-CE2 3.88Å; W150-Y157 AromaticContact CE3-CZ 3.86Å; W150-M169 HydrophobicContact CZ3-CE 4.41Å; W150-M169 HydrophobicContact CZ3-SD 4.21Å
151	S	88.9	Confident	89.9	Confident	2 Å²	2	41.5 Å²	41.5	1%	0.014	21%	0.205	C	C	.	.	H	α-helix	trans	-62.6	-40.5	173.6	-55.7	0	0	0	0	113	D147 R148 Y149 R161	D147-S151 WeakPolarHBondContact O-CB 3.36Å; D147-S151 PolarHBondContact O-N 3Å; D147-S151 PolarHBondContact O-OG 3.09Å; R148-S151 WeakPolarHBondContact O-CB 3.27Å; R148-S151 PolarHBondContact O-N 2.94Å; Y149-S151 VanDerWaalsContact C-N 3.32Å; Y149-S151 PolarHBondContact O-N 3.31Å; S151-R161 PolarHBondContact OG-NH2 2.98Å
152	V	86.6	Confident	89.7	Confident	7 Å²	7	44.8 Å²	44.8	4%	0.042	23%	0.226	C	C	.	.	H	α-helix	trans	-83.3	-26.3	-178.3	174.1	0	0	0	0	111.6	R148 Y149 I234 V237 A238 R241	R148-V152 WeakPolarHBondContact O-CB 3.16Å; R148-V152 WeakPolarHBondContact O-CG2 3.35Å; R148-V152 PolarHBondContact O-N 3.49Å; Y149-V152 PolarHBondContact O-N 2.87Å; V152-I234 HydrophobicContact CG2-CG2 4.48Å; V152-V237 HydrophobicContact CG1-CB 4.26Å; V152-V237 HydrophobicContact CG1-CG1 3.9Å; V152-V237 VanDerWaalsContact O-CG1 3.25Å; V152-V237 WeakPolarHBondContact O-CG1 3.47Å; V152-A238 HydrophobicContact CG1-CB 4.09Å; V152-R241 PolarHBondContact O-NE 3.44Å; V152-R241 PolarHBondContact O-NH1 3.07Å; V152-R241 PolarHBondContact O-NH2 3.38Å
153	A	87.5	Confident	89.5	Confident	20 Å²	20	49.5 Å²	49.5	17%	0.165	25%	0.245	C	C	.	.	H	α-helix	trans	-81.2	-43.2	175.8	0	0	0	0	0	113	Y149 R241	Y149-A153 HydrophobicContact CE2-CB 4.19Å; Y149-A153 WeakPolarHBondContact O-CB 3.35Å; Y149-A153 PolarHBondContact O-N 3.49Å; A153-R241 PolarHBondContact O-NH2 2.88Å
154	H	87	Confident	89.3	Confident	111 Å²	111	59.3 Å²	59.3	51%	0.514	28%	0.281	S	S	.	.			trans	-129.4	114	-171.6	-53.5	103.9	0	0	0	111.2	W150 A156 Y157	W150-H154 PolarHBondContact O-N 3.18Å; H154-A156 VanDerWaalsContact C-N 3.27Å; H154-A156 PolarHBondContact O-N 3.45Å; H154-Y157 WeakPolarHBondContact O-CB 3.34Å; H154-Y157 PolarHBondContact O-N 3.26Å; H154-Y157 VanDerWaalsContact O-N 3.11Å
155	I	81.1	Confident	89.3	Confident	59 Å²	59	64.4 Å²	64.4	30%	0.303	30%	0.3	S	S	.	.	H	α-helix	trans	-62.8	-38.6	179.6	-62.2	170.5	0	0	0	110.5	Y157 I158 V356	I155-Y157 PolarHBondContact O-N 2.87Å; I155-I158 WeakPolarHBondContact O-CB 3.41Å; I155-I158 PolarHBondContact O-N 3.33Å; I155-V356 HydrophobicContact CD1-CB 4.4Å; I155-V356 WeakPolarHBondContact CD1-O 3.49Å
156	A	87	Confident	89.3	Confident	54 Å²	54	64.4 Å²	64.4	45%	0.446	30%	0.3	S	S	.	.	H	α-helix	trans	-57.7	-29.1	175.5	0	0	0	0	0	113.7	H154 I158 Q159 H160	H154-A156 VanDerWaalsContact C-N 3.27Å; H154-A156 PolarHBondContact O-N 3.45Å; A156-I158 PolarHBondContact O-N 3.08Å; A156-Q159 PolarHBondContact O-N 3.11Å; A156-H160 PolarHBondContact O-N 3.23Å; A156-H160 VanDerWaalsContact O-N 3.08Å; A156-H160 PolarHBondContact O-ND1 3.36Å
157	Y	88.8	Confident	89.4	Confident	21 Å²	21	66.8 Å²	66.8	8%	0.082	31%	0.308	C	S	.	.	H	α-helix	trans	-64.3	-29.9	176	175	-97.5	0	0	0	112.4	D147 W150 H154 I155 Q159 R161	D147-Y157 PolarHBondContact OD1-OH 2.89Å; D147-Y157 VanDerWaalsContact OD1-OH 3.1Å; W150-Y157 HydrophobicContact CB-CD1 3.65Å; W150-Y157 HydrophobicContact CB-CD2 3.9Å; W150-Y157 HydrophobicContact CB-CE1 3.78Å; W150-Y157 HydrophobicContact CB-CE2 4.03Å; W150-Y157 HydrophobicContact CB-CG 3.71Å; W150-Y157 HydrophobicContact CD2-CE2 4.41Å; W150-Y157 AromaticContact CE3-CE2 3.88Å; W150-Y157 HydrophobicContact CE3-CE2 3.88Å; W150-Y157 AromaticContact CE3-CZ 3.86Å; H154-Y157 WeakPolarHBondContact O-CB 3.34Å; H154-Y157 PolarHBondContact O-N 3.26Å; H154-Y157 VanDerWaalsContact O-N 3.11Å; I155-Y157 PolarHBondContact O-N 2.87Å; Y157-Q159 VanDerWaalsContact C-N 3.32Å; Y157-Q159 PolarHBondContact O-N 3.1Å; Y157-R161 WeakPolarHBondContact O-CB 3.31Å; Y157-R161 PolarHBondContact O-N 3.45Å
158	I	82.3	Confident	89.5	Confident	55 Å²	55	70.4 Å²	70.4	28%	0.282	33%	0.33	S	S	.	.	H	α-helix	trans	-65.6	-39.4	177.9	-57.6	177.7	0	0	0	110.5	I155 A156	I155-I158 WeakPolarHBondContact O-CB 3.41Å; I155-I158 PolarHBondContact O-N 3.33Å; A156-I158 PolarHBondContact O-N 3.08Å
159	Q	79.1	Confident	89.8	Confident	153 Å²	153	71.3 Å²	71.3	72%	0.715	34%	0.335	S	S	*	.	H	α-helix	trans	-75.4	-41.6	179.9	-68.4	168.3	-37.5	0	0	112.3	A156 Y157 R161	A156-Q159 PolarHBondContact O-N 3.11Å; Y157-Q159 VanDerWaalsContact C-N 3.32Å; Y157-Q159 PolarHBondContact O-N 3.1Å; Q159-R161 PolarHBondContact O-N 3.19Å
160	H	81.6	Confident	90.1	Very high	140 Å²	140	69.2 Å²	69.2	65%	0.648	33%	0.328	S	S	*	.	S	Bend	trans	-92.9	15.5	-172.6	-60.3	87.7	0	0	0	114.5	A156 T162	A156-H160 PolarHBondContact O-N 3.23Å; A156-H160 VanDerWaalsContact O-N 3.08Å; A156-H160 PolarHBondContact O-ND1 3.36Å; H160-T162 PolarHBondContact O-N 2.7Å
161	R	87.3	Confident	90.4	Very high	20 Å²	20	68.7 Å²	68.7	8%	0.075	34%	0.34	C	S	.	.			trans	-74.8	100.2	-177.7	-169.6	-175.2	-41.2	-160.9	0.2	111.5	N84 H85 D147 S151 Y157 Q159 I166	N84-R161 HydrophobicContact CB-CG 4.4Å; N84-R161 PolarHBondContact ND2-O 3.14Å; H85-R161 PolarHBondContact ND1-NH1 2.97Å; D147-R161 WeakPolarHBondContact OD1-CD 3.33Å; D147-R161 IonicContact OD1-CZ 3.56Å; D147-R161 VanDerWaalsContact OD1-CZ 3.25Å; D147-R161 IonicContact OD1-NE 3.83Å; D147-R161 IonicContact OD1-NH1 3.27Å; D147-R161 PolarHBondContact OD1-NH1 2.83Å; D147-R161 IonicContact OD2-CZ 2.7Å; D147-R161 IonicContact OD2-NH1 3.35Å; D147-R161 PolarHBondContact OD2-NH1 3.32Å; S151-R161 PolarHBondContact OG-NH2 2.98Å; Y157-R161 WeakPolarHBondContact O-CB 3.31Å; Y157-R161 PolarHBondContact O-N 3.45Å; Q159-R161 PolarHBondContact O-N 3.19Å; R161-I166 HydrophobicContact CG-CD1 4.48Å; R161-I166 HydrophobicContact CG-CG1 4.49Å
162	T	92.3	Very high	90.9	Very high	73 Å²	73	72.9 Å²	72.9	45%	0.448	37%	0.365	S	S	.	.			trans	-78.1	155	178.4	65.6	0	0	0	0	112.9	H160 R164 R165	H160-T162 PolarHBondContact O-N 2.7Å; T162-R164 VanDerWaalsContact C-N 3.33Å; T162-R165 PolarHBondContact OG1-N 2.91Å
163	K	93.5	Very high	91.5	Very high	112 Å²	112	73 Å²	73	49%	0.487	37%	0.366	S	S	.	.	H	α-helix	trans	-60.4	-42.9	168.9	-73.1	-177.3	178.9	-176.9	0	111.5	N84 R165 I166 F167	N84-K163 WeakPolarHBondContact OD1-CG 3.46Å; K163-R165 VanDerWaalsContact C-N 3.32Å; K163-R165 PolarHBondContact O-N 2.99Å; K163-I166 PolarHBondContact O-N 3.21Å; K163-F167 HydrophobicContact CB-CD2 4.26Å; K163-F167 HydrophobicContact CB-CE2 4.33Å; K163-F167 WeakPolarHBondContact O-CD2 3.46Å; K163-F167 PolarHBondContact O-N 3.21Å
164	R	95.2	Very high	92	Very high	211 Å²	211	74.7 Å²	74.7	80%	0.796	37%	0.368	S	S	*	.	H	α-helix	trans	-50.8	-48.7	179.4	-173.4	176.1	179.1	179.7	0.2	111.6	T162 I166 F167 T168	T162-R164 VanDerWaalsContact C-N 3.33Å; R164-I166 VanDerWaalsContact C-N 3.34Å; R164-I166 PolarHBondContact O-N 3.34Å; R164-F167 PolarHBondContact O-N 2.98Å; R164-T168 PolarHBondContact O-N 3.18Å; R164-T168 PolarHBondContact O-OG1 2.65Å
165	R	94.9	Very high	92.5	Very high	113 Å²	113	71.3 Å²	71.3	43%	0.426	36%	0.363	S	S	.	.	H	α-helix	trans	-57.8	-44.2	177.7	-175.9	178.9	-67.8	-144.9	2	112.4	T162 K163 T168 M169	T162-R165 PolarHBondContact OG1-N 2.91Å; K163-R165 VanDerWaalsContact C-N 3.32Å; K163-R165 PolarHBondContact O-N 2.99Å; R165-T168 PolarHBondContact O-N 2.87Å; R165-M169 HydrophobicContact CG-SD 4.18Å; R165-M169 VanDerWaalsContact O-CG 3.31Å; R165-M169 WeakPolarHBondContact O-CG 3.49Å; R165-M169 PolarHBondContact O-N 3.36Å
166	I	96.4	Very high	93.4	Very high	0 Å²	0	71.3 Å²	71.3	0%	0	37%	0.366	C	S	.	.	H	α-helix	trans	-68.1	-44.1	-179.3	-60.7	-63	0	0	0	111.5	N84 L88 R161 K163 R164 T168 M169 I170	N84-I166 HydrophobicContact CB-CG1 4.11Å; N84-I166 WeakPolarHBondContact O-CG2 2.98Å; L88-I166 HydrophobicContact CD1-CD1 4.11Å; L88-I166 HydrophobicContact CD2-CG2 4.08Å; L88-I166 HydrophobicContact CG-CD1 4.42Å; L88-I166 HydrophobicContact CG-CG2 3.88Å; R161-I166 HydrophobicContact CG-CD1 4.48Å; R161-I166 HydrophobicContact CG-CG1 4.49Å; K163-I166 PolarHBondContact O-N 3.21Å; R164-I166 VanDerWaalsContact C-N 3.34Å; R164-I166 PolarHBondContact O-N 3.34Å; I166-T168 VanDerWaalsContact C-N 3.32Å; I166-T168 PolarHBondContact O-N 2.87Å; I166-M169 HydrophobicContact CD1-SD 4.21Å; I166-M169 WeakPolarHBondContact O-CB 3.42Å; I166-M169 PolarHBondContact O-N 2.97Å; I166-M169 VanDerWaalsContact O-N 3.13Å; I166-I170 HydrophobicContact CG2-CD1 4Å; I166-I170 WeakPolarHBondContact O-CG1 3.47Å; I166-I170 PolarHBondContact O-N 3.15Å
167	F	97.4	Very high	93.9	Very high	102 Å²	102	68.8 Å²	68.8	45%	0.447	35%	0.345	S	S	.	.	H	α-helix	trans	-65.5	-34.2	176	-76.4	-71	0	0	0	112.5	Y87 K163 R164 I170 A171	Y87-F167 HydrophobicContact CD1-CZ 4.44Å; Y87-F167 HydrophobicContact CD2-CE2 4.4Å; Y87-F167 HydrophobicContact CD2-CZ 4.43Å; Y87-F167 HydrophobicContact CG-CZ 4.32Å; K163-F167 HydrophobicContact CB-CD2 4.26Å; K163-F167 HydrophobicContact CB-CE2 4.33Å; K163-F167 WeakPolarHBondContact O-CD2 3.46Å; K163-F167 PolarHBondContact O-N 3.21Å; R164-F167 PolarHBondContact O-N 2.98Å; F167-I170 HydrophobicContact CD1-CD1 4.27Å; F167-I170 PolarHBondContact O-N 3.49Å; F167-A171 WeakPolarHBondContact O-CB 3.26Å; F167-A171 PolarHBondContact O-N 3.26Å
168	T	97.6	Very high	94.3	Very high	78 Å²	78	71.3 Å²	71.3	48%	0.479	36%	0.36	S	S	.	.	H	α-helix	trans	-62.7	-42.2	169.5	-58.1	0	0	0	0	111.8	R164 R165 I166 I170 A171 V172	R164-T168 PolarHBondContact O-N 3.18Å; R164-T168 PolarHBondContact O-OG1 2.65Å; R165-T168 PolarHBondContact O-N 2.87Å; I166-T168 VanDerWaalsContact C-N 3.32Å; I166-T168 PolarHBondContact O-N 2.87Å; T168-I170 PolarHBondContact O-N 2.96Å; T168-A171 PolarHBondContact O-N 3.25Å; T168-V172 WeakPolarHBondContact O-CG2 3.49Å; T168-V172 PolarHBondContact O-N 3.44Å
169	M	97.9	Very high	94.9	Very high	27 Å²	27	74.9 Å²	74.9	13%	0.133	38%	0.379	C	S	.	.	H	α-helix	trans	-61.7	-42.9	175	-69.7	167.8	68.4	0	0	111.7	L88 A143 L146 D147 W150 R165 I166 V172 V173	L88-M169 HydrophobicContact CD1-CE 4.27Å; L88-M169 HydrophobicContact CD2-CB 4.3Å; A143-M169 HydrophobicContact CB-CE 3.97Å; A143-M169 WeakPolarHBondContact O-CE 3.37Å; L146-M169 HydrophobicContact CB-CE 4.31Å; D147-M169 HydrophobicContact CB-CE 4.42Å; W150-M169 HydrophobicContact CZ3-CE 4.41Å; W150-M169 HydrophobicContact CZ3-SD 4.21Å; R165-M169 HydrophobicContact CG-SD 4.18Å; R165-M169 VanDerWaalsContact O-CG 3.31Å; R165-M169 WeakPolarHBondContact O-CG 3.49Å; R165-M169 PolarHBondContact O-N 3.36Å; I166-M169 HydrophobicContact CD1-SD 4.21Å; I166-M169 WeakPolarHBondContact O-CB 3.42Å; I166-M169 PolarHBondContact O-N 2.97Å; I166-M169 VanDerWaalsContact O-N 3.13Å; M169-V172 PolarHBondContact O-N 3.36Å; M169-V173 VanDerWaalsContact O-CG2 3.3Å; M169-V173 WeakPolarHBondContact O-CG2 3.32Å; M169-V173 PolarHBondContact O-N 3.03Å
170	I	98.6	Very high	95.7	Very high	20 Å²	20	68.7 Å²	68.7	10%	0.103	35%	0.35	C	S	.	.	H	α-helix	trans	-61.5	-47	175.6	-68	167.8	0	0	0	110.9	L88 S91 I166 F167 T168 V172 V173 W174	L88-I170 HydrophobicContact CD2-CD1 4.47Å; L88-I170 HydrophobicContact CD2-CG1 3.81Å; S91-I170 WeakPolarHBondContact OG-CG2 3.26Å; I166-I170 HydrophobicContact CG2-CD1 4Å; I166-I170 WeakPolarHBondContact O-CG1 3.47Å; I166-I170 PolarHBondContact O-N 3.15Å; F167-I170 HydrophobicContact CD1-CD1 4.27Å; F167-I170 PolarHBondContact O-N 3.49Å; T168-I170 PolarHBondContact O-N 2.96Å; I170-V172 PolarHBondContact O-N 2.83Å; I170-V173 PolarHBondContact O-N 3.07Å; I170-W174 VanDerWaalsContact O-CD1 3.32Å; I170-W174 PolarHBondContact O-N 3.19Å
171	A	98.5	Very high	96.2	Very high	65 Å²	65	62.1 Å²	62.1	54%	0.537	32%	0.32	S	S	.	.	H	α-helix	trans	-62.7	-40.2	179.1	0	0	0	0	0	112.5	F167 T168 G175	F167-A171 WeakPolarHBondContact O-CB 3.26Å; F167-A171 PolarHBondContact O-N 3.26Å; T168-A171 PolarHBondContact O-N 3.25Å; A171-G175 PolarHBondContact O-N 3.45Å
172	V	98.5	Very high	96.5	Very high	90 Å²	90	63 Å²	63	55%	0.545	33%	0.328	S	S	.	.	H	α-helix	trans	-64.1	-44.1	174.1	169.9	0	0	0	0	111.1	T168 M169 I170 G175 V176	T168-V172 WeakPolarHBondContact O-CG2 3.49Å; T168-V172 PolarHBondContact O-N 3.44Å; M169-V172 PolarHBondContact O-N 3.36Å; I170-V172 PolarHBondContact O-N 2.83Å; V172-G175 PolarHBondContact O-N 2.88Å; V172-V176 HydrophobicContact CG1-CG2 4.33Å; V172-V176 WeakPolarHBondContact O-CB 3.45Å; V172-V176 VanDerWaalsContact O-CG2 3.31Å; V172-V176 WeakPolarHBondContact O-CG2 3.33Å; V172-V176 PolarHBondContact O-N 3.36Å
173	V	98.6	Very high	96.5	Very high	10 Å²	10	61.2 Å²	61.2	6%	0.061	32%	0.317	C	S	.	.	H	α-helix	trans	-59.2	-51.2	177.8	165.1	0	0	0	0	111.4	L139 H140 A143 M169 I170 V176 A177	L139-V173 HydrophobicContact CB-CB 4.34Å; L139-V173 HydrophobicContact CB-CG1 3.65Å; L139-V173 HydrophobicContact CB-CG2 4.13Å; H140-V173 WeakPolarHBondContact CE1-CG1 3.42Å; H140-V173 WeakPolarHBondContact ND1-CG1 3.03Å; A143-V173 HydrophobicContact CB-CG2 3.92Å; M169-V173 VanDerWaalsContact O-CG2 3.3Å; M169-V173 WeakPolarHBondContact O-CG2 3.32Å; M169-V173 PolarHBondContact O-N 3.03Å; I170-V173 PolarHBondContact O-N 3.07Å; V173-V176 PolarHBondContact O-N 2.86Å; V173-A177 WeakPolarHBondContact O-CB 3.34Å; V173-A177 PolarHBondContact O-N 3.42Å
174	W	98.7	Very high	96.1	Very high	54 Å²	54	56.5 Å²	56.5	21%	0.205	30%	0.298	C	S	.	.	H	α-helix	trans	-65.7	-39.4	178.6	-77.3	107.8	0	0	0	112.7	S91 A95 M98 L132 A136 H140 I170 A177 L178	S91-W174 PolarHBondContact OG-NE1 2.88Å; A95-W174 HydrophobicContact CB-CH2 4.01Å; A95-W174 HydrophobicContact CB-CZ2 4.24Å; M98-W174 HydrophobicContact CE-CH2 4.31Å; M98-W174 HydrophobicContact CE-CZ3 4.19Å; L132-W174 HydrophobicContact CD1-CE3 4.42Å; L132-W174 HydrophobicContact CD1-CZ3 4.42Å; L132-W174 HydrophobicContact CD2-CZ3 4.48Å; L132-W174 HydrophobicContact CG-CZ3 4.23Å; A136-W174 HydrophobicContact CB-CE3 4.11Å; A136-W174 HydrophobicContact CB-CH2 4.06Å; A136-W174 HydrophobicContact CB-CZ3 3.84Å; H140-W174 AromaticContact CE1-CE2 3.81Å; H140-W174 AromaticContact CE1-NE1 3.55Å; H140-W174 AromaticContact NE2-NE1 3.77Å; I170-W174 VanDerWaalsContact O-CD1 3.32Å; I170-W174 PolarHBondContact O-N 3.19Å; W174-A177 PolarHBondContact O-N 3.46Å; W174-L178 WeakPolarHBondContact O-CB 3.49Å; W174-L178 VanDerWaalsContact O-CG 3.3Å; W174-L178 WeakPolarHBondContact O-CG 3.13Å; W174-L178 PolarHBondContact O-N 2.92Å
175	G	98.4	Very high	95.7	Very high	40 Å²	40	50.6 Å²	50.6	41%	0.412	28%	0.281	S	S	.	.	H	α-helix	trans	-62.4	-43.5	176.9	0	0	0	0	0	113.1	A171 V172 L179	A171-G175 PolarHBondContact O-N 3.45Å; V172-G175 PolarHBondContact O-N 2.88Å; G175-L179 WeakPolarHBondContact O-CB 3.5Å; G175-L179 PolarHBondContact O-N 3.31Å
176	V	98	Very high	95.4	Very high	60 Å²	60	53.3 Å²	53.3	36%	0.364	30%	0.296	S	S	.	.	H	α-helix	trans	-68.9	-40.9	176	175	0	0	0	0	111.2	L139 V172 V173 L178 L179 I180	L139-V176 HydrophobicContact CD1-CB 3.98Å; L139-V176 HydrophobicContact CD1-CG1 3.7Å; V172-V176 HydrophobicContact CG1-CG2 4.33Å; V172-V176 WeakPolarHBondContact O-CB 3.45Å; V172-V176 VanDerWaalsContact O-CG2 3.31Å; V172-V176 WeakPolarHBondContact O-CG2 3.33Å; V172-V176 PolarHBondContact O-N 3.36Å; V173-V176 PolarHBondContact O-N 2.86Å; V176-L178 PolarHBondContact O-N 3.28Å; V176-L179 PolarHBondContact O-N 2.95Å; V176-I180 HydrophobicContact CG1-CD1 3.89Å; V176-I180 WeakPolarHBondContact O-CG1 3.33Å; V176-I180 PolarHBondContact O-N 3.01Å; V176-I180 VanDerWaalsContact O-N 3.09Å
177	A	98.1	Very high	94.8	Very high	0 Å²	0	55.8 Å²	55.8	0%	0	32%	0.322	C	S	.	.	H	α-helix	trans	-62.4	-43	176.6	0	0	0	0	0	112.1	L132 T135 A136 L139 V173 W174 I180 S181	L132-A177 HydrophobicContact CD1-CB 3.87Å; T135-A177 HydrophobicContact CG2-CB 4.02Å; A136-A177 HydrophobicContact CB-CB 3.98Å; L139-A177 HydrophobicContact CD1-CB 4.27Å; V173-A177 WeakPolarHBondContact O-CB 3.34Å; V173-A177 PolarHBondContact O-N 3.42Å; W174-A177 PolarHBondContact O-N 3.46Å; A177-I180 PolarHBondContact O-N 3.1Å; A177-S181 WeakPolarHBondContact O-CB 3.48Å; A177-S181 PolarHBondContact O-N 3.36Å; A177-S181 PolarHBondContact O-OG 2.85Å
178	L	97.2	Very high	94.1	Very high	74 Å²	74	55.7 Å²	55.7	39%	0.387	33%	0.326	S	S	.	.	H	α-helix	trans	-60.7	-47.7	173.3	-74.9	166.5	0	0	0	111.5	F128 L132 W174 V176 I180 S181 V182	F128-L178 HydrophobicContact CZ-CD2 4.01Å; L132-L178 HydrophobicContact CD1-CB 4.47Å; L132-L178 HydrophobicContact CD1-CD2 3.71Å; L132-L178 HydrophobicContact CD1-CG 3.87Å; L132-L178 HydrophobicContact CD2-CD2 3.94Å; W174-L178 WeakPolarHBondContact O-CB 3.49Å; W174-L178 VanDerWaalsContact O-CG 3.3Å; W174-L178 WeakPolarHBondContact O-CG 3.13Å; W174-L178 PolarHBondContact O-N 2.92Å; V176-L178 PolarHBondContact O-N 3.28Å; L178-I180 VanDerWaalsContact C-N 3.25Å; L178-I180 PolarHBondContact O-N 2.74Å; L178-S181 PolarHBondContact O-N 3.44Å; L178-S181 VanDerWaalsContact O-N 3.09Å; L178-V182 WeakPolarHBondContact O-CB 3.31Å; L178-V182 WeakPolarHBondContact O-CG2 3.5Å; L178-V182 PolarHBondContact O-N 2.96Å
179	L	95.7	Very high	93.4	Very high	131 Å²	131	54 Å²	54	69%	0.686	31%	0.312	S	S	*	.	H	α-helix	trans	-57.5	-36.9	179.6	-178.1	62.9	0	0	0	112.9	G175 V176 P183	G175-L179 WeakPolarHBondContact O-CB 3.5Å; G175-L179 PolarHBondContact O-N 3.31Å; V176-L179 PolarHBondContact O-N 2.95Å; L179-P183 WeakPolarHBondContact O-CD 3.38Å
180	I	94.5	Very high	92.7	Very high	23 Å²	23	53.3 Å²	53.3	12%	0.118	31%	0.309	C	S	.	.	H	α-helix	trans	-76.1	-33.1	177.6	-68.3	168.3	0	0	0	112.1	V131 T135 V176 A177 L178 P183 L218 A219	V131-I180 HydrophobicContact CG1-CG2 4.49Å; T135-I180 HydrophobicContact CG2-CB 4.3Å; T135-I180 HydrophobicContact CG2-CD1 3.87Å; T135-I180 HydrophobicContact CG2-CG2 4.28Å; V176-I180 HydrophobicContact CG1-CD1 3.89Å; V176-I180 WeakPolarHBondContact O-CG1 3.33Å; V176-I180 PolarHBondContact O-N 3.01Å; V176-I180 VanDerWaalsContact O-N 3.09Å; A177-I180 PolarHBondContact O-N 3.1Å; L178-I180 VanDerWaalsContact C-N 3.25Å; L178-I180 PolarHBondContact O-N 2.74Å; I180-P183 VanDerWaalsContact O-CD 3.3Å; I180-P183 WeakPolarHBondContact O-CD 3.3Å; I180-L218 HydrophobicContact CD1-CB 4.12Å; I180-L218 HydrophobicContact CG1-CB 4.39Å; I180-A219 HydrophobicContact CG2-CB 4.05Å
181	S	94	Very high	92	Very high	2 Å²	2	57.2 Å²	57.2	1%	0.014	34%	0.335	C	S	.	.	H	α-helix	trans	-87.9	-27.1	-171.5	-49.8	0	0	0	0	114.2	L132 A177 L178 P183	L132-S181 WeakPolarHBondContact CA-OG 3.42Å; L132-S181 PolarHBondContact N-OG 3Å; A177-S181 WeakPolarHBondContact O-CB 3.48Å; A177-S181 PolarHBondContact O-N 3.36Å; A177-S181 PolarHBondContact O-OG 2.85Å; L178-S181 PolarHBondContact O-N 3.44Å; L178-S181 VanDerWaalsContact O-N 3.09Å; S181-P183 VanDerWaalsContact C-CD 3.45Å
182	V	93.2	Very high	91.4	Very high	38 Å²	38	58.2 Å²	58.2	23%	0.23	33%	0.331	C	S	.	.	S	Bend	trans	-69.5	-33.4	-176.2	164.1	0	0	0	0	116.4	F128 L178 P184 I185 F186	F128-V182 HydrophobicContact CE2-CG2 3.79Å; L178-V182 WeakPolarHBondContact O-CB 3.31Å; L178-V182 WeakPolarHBondContact O-CG2 3.5Å; L178-V182 PolarHBondContact O-N 2.96Å; V182-P184 VanDerWaalsContact C-CD 3.47Å; V182-P184 VanDerWaalsContact O-N 3.13Å; V182-I185 VanDerWaalsContact O-CB 3.3Å; V182-I185 WeakPolarHBondContact O-CB 3.4Å; V182-I185 PolarHBondContact O-N 3.4Å; V182-F186 HydrophobicContact CG1-CD2 3.49Å; V182-F186 VanDerWaalsContact CG1-CD2 3.49Å; V182-F186 HydrophobicContact CG1-CE2 3.31Å; V182-F186 HydrophobicContact CG1-CZ 4.44Å
183	P	90.8	Very high	90.9	Very high	35 Å²	35	54.2 Å²	54.2	23%	0.227	31%	0.306	C	S	.	.	G	3₁₀ helix	trans	-53.4	-37.7	-167.2	-27.5	34	0	0	0	117.4	L179 I180 S181 I185 F186 L188 Y211	L179-P183 WeakPolarHBondContact O-CD 3.38Å; I180-P183 VanDerWaalsContact O-CD 3.3Å; I180-P183 WeakPolarHBondContact O-CD 3.3Å; S181-P183 VanDerWaalsContact C-CD 3.45Å; P183-I185 PolarHBondContact O-N 3.06Å; P183-F186 PolarHBondContact O-N 3.13Å; P183-F186 VanDerWaalsContact O-N 3.1Å; P183-L188 HydrophobicContact CB-CB 4.2Å; P183-L188 HydrophobicContact CB-CD1 4.43Å; P183-L188 HydrophobicContact CB-CD2 4.15Å; P183-L188 HydrophobicContact CB-CG 4.5Å; P183-L188 PolarHBondContact O-N 3.49Å; P183-Y211 HydrophobicContact CB-CE2 4.34Å
184	P	86.7	Confident	90.6	Very high	13 Å²	13	57.2 Å²	57.2	8%	0.084	33%	0.325	C	S	.	.	G	3₁₀ helix	trans	-59	-29.9	174.4	-26.8	36.9	0	0	0	113.9	V182 F186 G187 K189 M205 Y211	V182-P184 VanDerWaalsContact C-CD 3.47Å; V182-P184 VanDerWaalsContact O-N 3.13Å; P184-F186 VanDerWaalsContact C-N 3.3Å; P184-F186 PolarHBondContact O-N 3.37Å; P184-G187 PolarHBondContact O-N 3.27Å; P184-K189 HydrophobicContact CB-CG 4.02Å; P184-K189 WeakPolarHBondContact O-CE 3.3Å; P184-K189 PolarHBondContact O-NZ 3.39Å; P184-M205 HydrophobicContact CG-CE 4.29Å; P184-M205 HydrophobicContact CG-SD 4.3Å; P184-Y211 HydrophobicContact CG-CE1 4.29Å; P184-Y211 HydrophobicContact CG-CE2 4.03Å; P184-Y211 WeakPolarHBondContact CG-OH 3.45Å
185	I	86.9	Confident	90.2	Very high	88 Å²	88	58 Å²	58	45%	0.451	33%	0.331	S	S	.	.	G	3₁₀ helix	trans	-65.7	-36.1	178.1	-58.3	177.6	0	0	0	110.5	F128 V182 P183 G187	F128-I185 HydrophobicContact CB-CD1 4.22Å; F128-I185 HydrophobicContact CD2-CD1 3.53Å; F128-I185 HydrophobicContact CD2-CG1 4.49Å; F128-I185 HydrophobicContact CE2-CD1 4.03Å; F128-I185 HydrophobicContact CG-CD1 3.88Å; V182-I185 VanDerWaalsContact O-CB 3.3Å; V182-I185 WeakPolarHBondContact O-CB 3.4Å; V182-I185 PolarHBondContact O-N 3.4Å; P183-I185 PolarHBondContact O-N 3.06Å; I185-G187 VanDerWaalsContact C-N 3.25Å; I185-G187 PolarHBondContact O-N 3.05Å
186	F	87.8	Confident	89.8	Confident	169 Å²	169	58 Å²	58	74%	0.741	32%	0.319	S	S	*	.	G	3₁₀ helix	trans	-86.5	17	176.3	-67.2	-58.7	0	0	0	114.1	V182 P183 P184	V182-F186 HydrophobicContact CG1-CD2 3.49Å; V182-F186 VanDerWaalsContact CG1-CD2 3.49Å; V182-F186 HydrophobicContact CG1-CE2 3.31Å; V182-F186 HydrophobicContact CG1-CZ 4.44Å; P183-F186 PolarHBondContact O-N 3.13Å; P183-F186 VanDerWaalsContact O-N 3.1Å; P184-F186 VanDerWaalsContact C-N 3.3Å; P184-F186 PolarHBondContact O-N 3.37Å
187	G	83.1	Confident	89.4	Confident	53 Å²	53	55.2 Å²	55.2	55%	0.546	30%	0.301	S	S	.	.	T	Hydrogen-bonded Turn	trans	93.7	7.1	171.5	0	0	0	0	0	115.8	P184 I185 K189	P184-G187 PolarHBondContact O-N 3.27Å; I185-G187 VanDerWaalsContact C-N 3.25Å; I185-G187 PolarHBondContact O-N 3.05Å; G187-K189 PolarHBondContact O-N 3.47Å
188	L	83.6	Confident	89.2	Confident	99 Å²	99	58.3 Å²	58.3	52%	0.518	32%	0.318	S	S	.	.			trans	-76.8	69.8	168.1	-74	79.4	0	0	0	110	P183 Y211	P183-L188 HydrophobicContact CB-CB 4.2Å; P183-L188 HydrophobicContact CB-CD1 4.43Å; P183-L188 HydrophobicContact CB-CD2 4.15Å; P183-L188 HydrophobicContact CB-CG 4.5Å; P183-L188 PolarHBondContact O-N 3.49Å; L188-Y211 HydrophobicContact CB-CD2 4.31Å
189	K	82.9	Confident	88.8	Confident	43 Å²	43	60.8 Å²	60.8	19%	0.187	32%	0.322	C	S	.	.	S	Bend	trans	-129.8	153.7	178.5	-70.4	173.3	169.9	123.3	0	109.4	E124 P184 G187 F193 S206	E124-K189 IonicContact OE1-NZ 2.65Å; E124-K189 PolarHBondContact OE1-NZ 3.27Å; P184-K189 HydrophobicContact CB-CG 4.02Å; P184-K189 WeakPolarHBondContact O-CE 3.3Å; P184-K189 PolarHBondContact O-NZ 3.39Å; G187-K189 PolarHBondContact O-N 3.47Å; K189-F193 HydrophobicContact CB-CB 4.1Å; K189-F193 HydrophobicContact CB-CG 4.26Å; K189-F193 HydrophobicContact CD-CB 4.46Å; K189-F193 HydrophobicContact CD-CD1 3.65Å; K189-F193 HydrophobicContact CD-CD2 4.27Å; K189-F193 HydrophobicContact CD-CE1 3.87Å; K189-F193 HydrophobicContact CD-CE2 4.46Å; K189-F193 HydrophobicContact CD-CG 3.87Å; K189-F193 HydrophobicContact CD-CZ 4.28Å; K189-F193 HydrophobicContact CG-CD2 4.41Å; K189-F193 HydrophobicContact CG-CG 4.31Å; K189-S206 WeakPolarHBondContact CA-OG 3.26Å
190	D	82.9	Confident	88.5	Confident	13 Å²	13	60.4 Å²	60.4	7%	0.07	32%	0.315	C	S	.	.			trans	-63.9	147	171.6	70.6	-93.4	0	0	0	111.4	L192 F193 R196 S206 Q207 D208	D190-L192 PolarHBondContact O-N 2.92Å; D190-L192 WeakPolarHBondContact OD2-CA 3.2Å; D190-L192 WeakPolarHBondContact OD2-CB 3.45Å; D190-L192 PolarHBondContact OD2-N 2.82Å; D190-F193 VanDerWaalsContact O-CB 3.27Å; D190-F193 WeakPolarHBondContact O-CB 3.35Å; D190-F193 PolarHBondContact O-N 3.04Å; D190-F193 PolarHBondContact OD2-N 3.21Å; D190-F193 VanDerWaalsContact OD2-N 3.09Å; D190-R196 VanDerWaalsContact CG-NH2 3.32Å; D190-R196 IonicContact OD1-NH2 2.63Å; D190-R196 PolarHBondContact OD1-NH2 2.73Å; D190-R196 IonicContact OD2-CZ 3.61Å; D190-R196 IonicContact OD2-NH2 3.65Å; D190-R196 PolarHBondContact OD2-NH2 2.85Å; D190-S206 PolarHBondContact N-OG 2.88Å; D190-S206 WeakPolarHBondContact OD1-CA 3.29Å; D190-Q207 PolarHBondContact OD1-N 3.04Å; D190-D208 HydrophobicContact CB-CB 4.27Å
191	P	84.5	Confident	88.4	Confident	101 Å²	101	62.7 Å²	62.7	66%	0.656	33%	0.325	S	S	*	.	T	Hydrogen-bonded Turn	trans	-58.4	-21.8	-176.9	-27.3	35.7	0	0	0	115
192	L	86	Confident	88.2	Confident	87 Å²	87	64.1 Å²	64.1	46%	0.455	33%	0.333	S	S	.	.	T	Hydrogen-bonded Turn	trans	-91.9	-2.2	-179.2	-59.2	176.4	0	0	0	112.8	D190 T194 E195 R196	D190-L192 PolarHBondContact O-N 2.92Å; D190-L192 WeakPolarHBondContact OD2-CA 3.2Å; D190-L192 WeakPolarHBondContact OD2-CB 3.45Å; D190-L192 PolarHBondContact OD2-N 2.82Å; L192-T194 PolarHBondContact O-N 3.28Å; L192-E195 PolarHBondContact O-N 3.09Å; L192-R196 VanDerWaalsContact O-CB 3.23Å; L192-R196 WeakPolarHBondContact O-CB 3.43Å; L192-R196 PolarHBondContact O-N 3.03Å
193	F	88.4	Confident	88.1	Confident	5 Å²	5	62.4 Å²	62.4	2%	0.022	32%	0.323	C	S	.	.	H	α-helix	trans	-54.2	-48.8	-175.2	-179	-86.5	0	0	0	112.9	L120 E124 K189 D190 R196 V197 L204	L120-F193 HydrophobicContact CD1-CD1 3.99Å; L120-F193 HydrophobicContact CD1-CE1 3.68Å; E124-F193 HydrophobicContact CG-CE1 4.18Å; E124-F193 HydrophobicContact CG-CZ 4.43Å; K189-F193 HydrophobicContact CB-CB 4.1Å; K189-F193 HydrophobicContact CB-CG 4.26Å; K189-F193 HydrophobicContact CD-CB 4.46Å; K189-F193 HydrophobicContact CD-CD1 3.65Å; K189-F193 HydrophobicContact CD-CD2 4.27Å; K189-F193 HydrophobicContact CD-CE1 3.87Å; K189-F193 HydrophobicContact CD-CE2 4.46Å; K189-F193 HydrophobicContact CD-CG 3.87Å; K189-F193 HydrophobicContact CD-CZ 4.28Å; K189-F193 HydrophobicContact CG-CD2 4.41Å; K189-F193 HydrophobicContact CG-CG 4.31Å; D190-F193 VanDerWaalsContact O-CB 3.27Å; D190-F193 WeakPolarHBondContact O-CB 3.35Å; D190-F193 PolarHBondContact O-N 3.04Å; D190-F193 PolarHBondContact OD2-N 3.21Å; D190-F193 VanDerWaalsContact OD2-N 3.09Å; F193-R196 WeakPolarHBondContact O-CB 3.47Å; F193-R196 PolarHBondContact O-N 3.38Å; F193-V197 HydrophobicContact CD1-CG2 4.49Å; F193-V197 HydrophobicContact CE1-CG2 4.18Å; F193-V197 HydrophobicContact CZ-CG2 4.29Å; F193-V197 WeakPolarHBondContact O-CG2 3.46Å; F193-V197 PolarHBondContact O-N 3.1Å; F193-V197 VanDerWaalsContact O-N 3.11Å; F193-L204 VanDerWaalsContact CE2-O 3.31Å; F193-L204 WeakPolarHBondContact CE2-O 3.41Å
194	T	90.7	Very high	87.9	Confident	74 Å²	74	61.9 Å²	61.9	45%	0.454	32%	0.318	S	S	.	.	H	α-helix	trans	-64.6	-44.2	-179.2	-56	0	0	0	0	111.7	L120 L192 V197 D198	L120-T194 HydrophobicContact CD1-CG2 4.4Å; L120-T194 HydrophobicContact CD2-CG2 4.06Å; L192-T194 PolarHBondContact O-N 3.28Å; T194-V197 PolarHBondContact O-N 2.89Å; T194-D198 WeakPolarHBondContact O-CB 3.29Å; T194-D198 PolarHBondContact O-N 3.06Å
195	E	90.1	Very high	87.9	Confident	69 Å²	69	62.7 Å²	62.7	32%	0.322	32%	0.321	S	S	.	.	H	α-helix	trans	-66.1	-40.9	178.2	-169.4	-178.8	-173.2	0	0	111.7	L192 V197 R199 F200	L192-E195 PolarHBondContact O-N 3.09Å; E195-V197 VanDerWaalsContact C-N 3.28Å; E195-V197 PolarHBondContact O-N 3.28Å; E195-R199 HydrophobicContact CG-CB 3.84Å; E195-R199 WeakPolarHBondContact O-CA 3.39Å; E195-R199 VanDerWaalsContact O-CB 3.24Å; E195-R199 WeakPolarHBondContact O-CB 3.41Å; E195-R199 PolarHBondContact O-N 3.1Å; E195-R199 WeakPolarHBondContact OE1-CD 3.32Å; E195-R199 IonicContact OE1-CZ 3.7Å; E195-R199 IonicContact OE1-NE 2.69Å; E195-R199 IonicContact OE1-NH1 3.26Å; E195-R199 PolarHBondContact OE1-NH1 3.19Å; E195-F200 HydrophobicContact CG-CD2 4.15Å; E195-F200 HydrophobicContact CG-CE2 3.82Å; E195-F200 PolarHBondContact O-N 3.22Å; E195-F200 VanDerWaalsContact O-N 3.17Å
196	R	90.2	Very high	87.8	Confident	41 Å²	41	58.5 Å²	58.5	16%	0.155	30%	0.3	C	S	.	.	H	α-helix	trans	-53.8	-44.5	174.4	-168.2	-163.2	-52.8	-84.1	-2.7	111.6	D190 L192 F193 F200 K201 V202	D190-R196 VanDerWaalsContact CG-NH2 3.32Å; D190-R196 IonicContact OD1-NH2 2.63Å; D190-R196 PolarHBondContact OD1-NH2 2.73Å; D190-R196 IonicContact OD2-CZ 3.61Å; D190-R196 IonicContact OD2-NH2 3.65Å; D190-R196 PolarHBondContact OD2-NH2 2.85Å; L192-R196 VanDerWaalsContact O-CB 3.23Å; L192-R196 WeakPolarHBondContact O-CB 3.43Å; L192-R196 PolarHBondContact O-N 3.03Å; F193-R196 WeakPolarHBondContact O-CB 3.47Å; F193-R196 PolarHBondContact O-N 3.38Å; R196-F200 CarbonylContact O-C 3.45Å; R196-F200 WeakPolarHBondContact O-CB 3.48Å; R196-K201 PolarHBondContact O-N 3.15Å; R196-K201 VanDerWaalsContact O-N 3.14Å; R196-V202 CarbonylContact C-O 3.58Å; R196-V202 HydrophobicContact CG-CB 4.01Å; R196-V202 HydrophobicContact CG-CG1 4.01Å; R196-V202 WeakPolarHBondContact CG-O 3.42Å; R196-V202 PolarHBondContact O-N 3.5Å
197	V	91.2	Very high	87.5	Confident	1 Å²	1	52.3 Å²	52.3	1%	0.006	27%	0.273	C	S	.	.	H	α-helix	trans	-78.8	-49.6	-179.7	-178.8	0	0	0	0	112	L120 C123 F193 T194 E195 K201	L120-V197 HydrophobicContact CD1-CB 3.97Å; L120-V197 HydrophobicContact CD1-CG1 4.18Å; L120-V197 HydrophobicContact CD1-CG2 4.24Å; C123-V197 HydrophobicContact CB-CG1 3.96Å; C123-V197 HydrophobicContact CB-CG2 4.24Å; C123-V197 VanDerWaalsContact SG-CG2 3.6Å; F193-V197 HydrophobicContact CD1-CG2 4.49Å; F193-V197 HydrophobicContact CE1-CG2 4.18Å; F193-V197 HydrophobicContact CZ-CG2 4.29Å; F193-V197 WeakPolarHBondContact O-CG2 3.46Å; F193-V197 PolarHBondContact O-N 3.1Å; F193-V197 VanDerWaalsContact O-N 3.11Å; T194-V197 PolarHBondContact O-N 2.89Å; E195-V197 VanDerWaalsContact C-N 3.28Å; E195-V197 PolarHBondContact O-N 3.28Å; V197-K201 VanDerWaalsContact O-CA 3.27Å; V197-K201 WeakPolarHBondContact O-CA 3.15Å; V197-K201 PolarHBondContact O-N 3.06Å
198	D	92.1	Very high	87.5	Confident	66 Å²	66	53 Å²	53	35%	0.353	26%	0.264	S	S	.	.	H	α-helix	trans	-83.9	-36.6	-170.6	-72.6	-33.2	0	0	0	113.7	T194 K201	T194-D198 WeakPolarHBondContact O-CB 3.29Å; T194-D198 PolarHBondContact O-N 3.06Å; D198-K201 WeakPolarHBondContact O-CE 3.13Å; D198-K201 PolarHBondContact O-NZ 3.17Å
199	R	89.7	Confident	87.6	Confident	125 Å²	125	52.2 Å²	52.2	47%	0.472	26%	0.26	S	S	.	.	T	Hydrogen-bonded Turn	trans	-90.8	-53.1	178.8	-171.5	-175.2	-173.5	170.7	3.2	111.7	E195	E195-R199 HydrophobicContact CG-CB 3.84Å; E195-R199 WeakPolarHBondContact O-CA 3.39Å; E195-R199 VanDerWaalsContact O-CB 3.24Å; E195-R199 WeakPolarHBondContact O-CB 3.41Å; E195-R199 PolarHBondContact O-N 3.1Å; E195-R199 WeakPolarHBondContact OE1-CD 3.32Å; E195-R199 IonicContact OE1-CZ 3.7Å; E195-R199 IonicContact OE1-NE 2.69Å; E195-R199 IonicContact OE1-NH1 3.26Å; E195-R199 PolarHBondContact OE1-NH1 3.19Å
200	F	89.6	Confident	87.7	Confident	123 Å²	123	55.5 Å²	55.5	54%	0.539	28%	0.278	S	S	.	.	S	Bend	trans	-85.7	-8.8	-174.5	-60.9	-75.8	0	0	0	113.8	E195 R196 V202	E195-F200 HydrophobicContact CG-CD2 4.15Å; E195-F200 HydrophobicContact CG-CE2 3.82Å; E195-F200 PolarHBondContact O-N 3.22Å; E195-F200 VanDerWaalsContact O-N 3.17Å; R196-F200 CarbonylContact O-C 3.45Å; R196-F200 WeakPolarHBondContact O-CB 3.48Å; F200-V202 PolarHBondContact O-N 3.49Å
201	K	91.1	Very high	87.9	Confident	72 Å²	72	55.9 Å²	55.9	31%	0.313	28%	0.279	S	S	.	.			trans	56.5	36.7	-179.7	-51.2	-53.6	-173.1	-171.3	0	112.8	K115 W116 R196 V197 D198	K115-K201 HydrophobicContact CB-CB 4.02Å; K115-K201 HydrophobicContact CG-CB 4.48Å; W116-K201 PolarHBondContact N-O 3.14Å; W116-K201 WeakPolarHBondContact O-CD 3.45Å; R196-K201 PolarHBondContact O-N 3.15Å; R196-K201 VanDerWaalsContact O-N 3.14Å; V197-K201 VanDerWaalsContact O-CA 3.27Å; V197-K201 WeakPolarHBondContact O-CA 3.15Å; V197-K201 PolarHBondContact O-N 3.06Å; D198-K201 WeakPolarHBondContact O-CE 3.13Å; D198-K201 PolarHBondContact O-NZ 3.17Å
202	V	89.8	Confident	88.1	Confident	32 Å²	32	51.8 Å²	51.8	19%	0.194	25%	0.251	C	S	.	.			trans	-114.6	110	177.9	168.6	0	0	0	0	108.7	R196 F200 L204	R196-V202 CarbonylContact C-O 3.58Å; R196-V202 HydrophobicContact CG-CB 4.01Å; R196-V202 HydrophobicContact CG-CG1 4.01Å; R196-V202 WeakPolarHBondContact CG-O 3.42Å; R196-V202 PolarHBondContact O-N 3.5Å; F200-V202 PolarHBondContact O-N 3.49Å; V202-L204 HydrophobicContact CG1-CB 4.45Å; V202-L204 HydrophobicContact CG1-CD1 3.59Å; V202-L204 HydrophobicContact CG1-CG 3.65Å
203	C	91.6	Very high	88.3	Confident	2 Å²	2	50.5 Å²	50.5	1%	0.014	25%	0.245	C	C	.	.			trans	-92.2	106	170.9	-177.9	0	0	0	0	109.2	W116 C123 W126 N127	W116-C203 HydrophobicContact CB-CB 3.79Å; W116-C203 HydrophobicContact CD2-CB 3.59Å; W116-C203 HydrophobicContact CE3-CB 3.85Å; W116-C203 HydrophobicContact CG-CB 3.54Å; C123-C203 WeakPolarHBondContact CA-SG 3.04Å; C123-C203 HydrophobicContact CB-CB 3.88Å; C123-C203 WeakPolarHBondContact CB-SG 3.49Å; C123-C203 VanDerWaalsContact SG-CA 3.52Å; C123-C203 WeakPolarHBondContact SG-CB 3.46Å; C123-C203 CovalentContact SG-SG 2.03Å; C123-C203 PolarHBondContact SG-SG 2.72Å; W126-C203 HydrophobicContact CE3-CB 4.22Å; W126-C203 VanDerWaalsContact CE3-SG 3.55Å; W126-C203 HydrophobicContact CZ3-CB 4.01Å; N127-C203 PolarHBondContact ND2-SG 3.36Å
204	L	87.2	Confident	88.4	Confident	23 Å²	23	56.6 Å²	56.6	12%	0.12	27%	0.271	C	S	.	.			trans	-131.7	154.9	172.1	-70.1	172.9	0	0	0	108.3	F193 V202	F193-L204 VanDerWaalsContact CE2-O 3.31Å; F193-L204 WeakPolarHBondContact CE2-O 3.41Å; V202-L204 HydrophobicContact CG1-CB 4.45Å; V202-L204 HydrophobicContact CG1-CD1 3.59Å; V202-L204 HydrophobicContact CG1-CG 3.65Å
205	M	86	Confident	88.4	Confident	30 Å²	30	53.7 Å²	53.7	15%	0.148	25%	0.254	C	S	.	.			trans	-55.4	156.8	167.4	-176	54.5	129	0	0	111.3	N127 V131 P184 Q207 Y211	N127-M205 PolarHBondContact OD1-N 3.1Å; V131-M205 HydrophobicContact CG2-CE 3.44Å; V131-M205 VanDerWaalsContact CG2-CE 3.44Å; P184-M205 HydrophobicContact CG-CE 4.29Å; P184-M205 HydrophobicContact CG-SD 4.3Å; M205-Q207 PolarHBondContact O-N 3.47Å; M205-Q207 PolarHBondContact O-NE2 2.66Å; M205-Y211 HydrophobicContact CE-CE1 3.8Å; M205-Y211 WeakPolarHBondContact CE-OH 3.46Å; M205-Y211 HydrophobicContact CG-CE1 4.2Å; M205-Y211 HydrophobicContact SD-CE1 3.93Å
206	S	84.3	Confident	88.5	Confident	1 Å²	1	50.7 Å²	50.7	1%	0.007	24%	0.24	C	C	.	.			trans	-46.4	127.9	175.5	178.1	0	0	0	0	112	K189 D190 D208	K189-S206 WeakPolarHBondContact CA-OG 3.26Å; D190-S206 PolarHBondContact N-OG 2.88Å; D190-S206 WeakPolarHBondContact OD1-CA 3.29Å; S206-D208 VanDerWaalsContact C-N 3.34Å; S206-D208 PolarHBondContact OG-N 3.18Å
207	Q	82.2	Confident	88.7	Confident	38 Å²	38	52 Å²	52	18%	0.178	25%	0.25	C	C	.	.			trans	-92	8.7	179.6	-61.1	-59.5	-70.7	0	0	113.4	D190 M205 L209	D190-Q207 PolarHBondContact OD1-N 3.04Å; M205-Q207 PolarHBondContact O-N 3.47Å; M205-Q207 PolarHBondContact O-NE2 2.66Å; Q207-L209 PolarHBondContact O-N 2.91Å
208	D	83.7	Confident	88.9	Confident	67 Å²	67	56.2 Å²	56.2	36%	0.358	27%	0.271	S	S	.	.			trans	-62.9	126.7	172.4	175.3	-98.6	0	0	0	110.5	D190 S206 I210 Y211 Q212	D190-D208 HydrophobicContact CB-CB 4.27Å; S206-D208 VanDerWaalsContact C-N 3.34Å; S206-D208 PolarHBondContact OG-N 3.18Å; D208-I210 VanDerWaalsContact C-N 3.35Å; D208-I210 PolarHBondContact O-N 3.29Å; D208-I210 WeakPolarHBondContact OD1-CB 3.21Å; D208-I210 PolarHBondContact OD1-N 3.42Å; D208-I210 VanDerWaalsContact OD1-N 3.15Å; D208-Y211 PolarHBondContact O-N 3.15Å; D208-Y211 WeakPolarHBondContact OD1-CB 3.36Å; D208-Y211 PolarHBondContact OD1-N 3.01Å; D208-Q212 VanDerWaalsContact O-CB 3.23Å; D208-Q212 WeakPolarHBondContact O-CB 3.42Å; D208-Q212 PolarHBondContact O-N 3.1Å
209	L	84.9	Confident	89	Confident	84 Å²	84	53.3 Å²	53.3	44%	0.44	26%	0.257	S	S	.	.	H	α-helix	trans	-60.6	-43.5	-173.7	176.5	65.2	0	0	0	111.9	Q207 L213 P391	Q207-L209 PolarHBondContact O-N 2.91Å; L209-L213 HydrophobicContact CD1-CD1 3.81Å; L209-L213 HydrophobicContact CD1-CG 4.07Å; L209-L213 HydrophobicContact CG-CD1 4.01Å; L209-L213 WeakPolarHBondContact O-CB 3.22Å; L209-L213 WeakPolarHBondContact O-CG 3.24Å; L209-L213 PolarHBondContact O-N 3.12Å; L209-P391 HydrophobicContact CD1-CB 3.5Å; L209-P391 VanDerWaalsContact CD1-CB 3.5Å; L209-P391 HydrophobicContact CD1-CG 4.4Å
210	I	86.3	Confident	89.3	Confident	111 Å²	111	47.4 Å²	47.4	57%	0.569	24%	0.235	S	C	*	.	H	α-helix	trans	-67.8	-51.7	-176.5	-63.7	176.7	0	0	0	108.9	D208 Q212 L213 F214	D208-I210 VanDerWaalsContact C-N 3.35Å; D208-I210 PolarHBondContact O-N 3.29Å; D208-I210 WeakPolarHBondContact OD1-CB 3.21Å; D208-I210 PolarHBondContact OD1-N 3.42Å; D208-I210 VanDerWaalsContact OD1-N 3.15Å; I210-Q212 PolarHBondContact O-N 3.41Å; I210-L213 PolarHBondContact O-N 3.42Å; I210-F214 HydrophobicContact CG2-CD2 3.73Å; I210-F214 HydrophobicContact CG2-CE2 3.89Å; I210-F214 VanDerWaalsContact O-CD2 3.3Å; I210-F214 WeakPolarHBondContact O-CD2 3.16Å; I210-F214 PolarHBondContact O-N 2.89Å
211	Y	86.5	Confident	89.7	Confident	21 Å²	21	44.1 Å²	44.1	8%	0.082	22%	0.219	C	C	.	.	H	α-helix	trans	-55.4	-50.6	176.6	175.9	-95.9	0	0	0	111.7	P183 P184 L188 M205 D208 L213 F214 S215	P183-Y211 HydrophobicContact CB-CE2 4.34Å; P184-Y211 HydrophobicContact CG-CE1 4.29Å; P184-Y211 HydrophobicContact CG-CE2 4.03Å; P184-Y211 WeakPolarHBondContact CG-OH 3.45Å; L188-Y211 HydrophobicContact CB-CD2 4.31Å; M205-Y211 HydrophobicContact CE-CE1 3.8Å; M205-Y211 WeakPolarHBondContact CE-OH 3.46Å; M205-Y211 HydrophobicContact CG-CE1 4.2Å; M205-Y211 HydrophobicContact SD-CE1 3.93Å; D208-Y211 PolarHBondContact O-N 3.15Å; D208-Y211 WeakPolarHBondContact OD1-CB 3.36Å; D208-Y211 PolarHBondContact OD1-N 3.01Å; Y211-L213 PolarHBondContact O-N 3.23Å; Y211-F214 PolarHBondContact O-N 3.47Å; Y211-S215 WeakPolarHBondContact O-CB 3.49Å; Y211-S215 PolarHBondContact O-N 3.24Å; Y211-S215 PolarHBondContact OH-OG 3.43Å
212	Q	87.7	Confident	90	Very high	16 Å²	16	43.8 Å²	43.8	8%	0.075	22%	0.223	C	C	.	.	H	α-helix	trans	-65.2	-40.6	-175.8	-176.1	66.3	0.2	0	0	111.9	D208 I210 T216 A387 P391	D208-Q212 VanDerWaalsContact O-CB 3.23Å; D208-Q212 WeakPolarHBondContact O-CB 3.42Å; D208-Q212 PolarHBondContact O-N 3.1Å; I210-Q212 PolarHBondContact O-N 3.41Å; Q212-T216 WeakPolarHBondContact O-CB 3.21Å; Q212-T216 VanDerWaalsContact O-CG2 3.26Å; Q212-T216 WeakPolarHBondContact O-CG2 3.22Å; Q212-T216 PolarHBondContact O-N 3.45Å; Q212-T216 PolarHBondContact O-OG1 3.37Å; Q212-A387 WeakPolarHBondContact CG-O 3Å; Q212-A387 PolarHBondContact NE2-O 2.8Å; Q212-P391 HydrophobicContact CB-CG 3.92Å; Q212-P391 HydrophobicContact CG-CG 3.54Å
213	L	90.1	Very high	90.4	Very high	60 Å²	60	42.4 Å²	42.4	31%	0.314	22%	0.215	S	C	.	.	H	α-helix	trans	-63.8	-52.6	174.8	-72.1	175.3	0	0	0	111.7	L209 I210 Y211 S215 T216 I217 L388	L209-L213 HydrophobicContact CD1-CD1 3.81Å; L209-L213 HydrophobicContact CD1-CG 4.07Å; L209-L213 HydrophobicContact CG-CD1 4.01Å; L209-L213 WeakPolarHBondContact O-CB 3.22Å; L209-L213 WeakPolarHBondContact O-CG 3.24Å; L209-L213 PolarHBondContact O-N 3.12Å; I210-L213 PolarHBondContact O-N 3.42Å; Y211-L213 PolarHBondContact O-N 3.23Å; L213-S215 PolarHBondContact O-N 2.87Å; L213-T216 PolarHBondContact O-OG1 2.8Å; L213-I217 WeakPolarHBondContact O-CB 3.26Å; L213-I217 WeakPolarHBondContact O-CD1 3.49Å; L213-I217 WeakPolarHBondContact O-CG1 3.45Å; L213-I217 PolarHBondContact O-N 3.29Å; L213-L388 HydrophobicContact CD2-CD2 3.68Å
214	F	90.7	Very high	90.7	Very high	133 Å²	133	43.2 Å²	43.2	58%	0.583	22%	0.219	S	C	*	.	H	α-helix	trans	-65.2	-41.4	-179	-81.1	-71.4	0	0	0	112.4	I210 Y211 I217 L218	I210-F214 HydrophobicContact CG2-CD2 3.73Å; I210-F214 HydrophobicContact CG2-CE2 3.89Å; I210-F214 VanDerWaalsContact O-CD2 3.3Å; I210-F214 WeakPolarHBondContact O-CD2 3.16Å; I210-F214 PolarHBondContact O-N 2.89Å; Y211-F214 PolarHBondContact O-N 3.47Å; F214-I217 PolarHBondContact O-N 3.4Å; F214-L218 WeakPolarHBondContact O-CB 3.45Å; F214-L218 VanDerWaalsContact O-CG 3.29Å; F214-L218 WeakPolarHBondContact O-CG 3.11Å; F214-L218 PolarHBondContact O-N 3.06Å
215	S	90.9	Very high	91.2	Very high	13 Å²	13	47 Å²	47	9%	0.091	24%	0.239	C	C	.	.	H	α-helix	trans	-62.6	-50.8	178.9	-172.7	0	0	0	0	111.3	Y211 L213 I217 L218 A219	Y211-S215 WeakPolarHBondContact O-CB 3.49Å; Y211-S215 PolarHBondContact O-N 3.24Å; Y211-S215 PolarHBondContact OH-OG 3.43Å; L213-S215 PolarHBondContact O-N 2.87Å; S215-I217 PolarHBondContact O-N 3.5Å; S215-L218 PolarHBondContact O-N 2.95Å; S215-A219 WeakPolarHBondContact O-CB 3.27Å; S215-A219 PolarHBondContact O-N 3.35Å
216	T	92.9	Very high	91.7	Very high	5 Å²	5	49.3 Å²	49.3	3%	0.031	25%	0.251	C	S	.	.	H	α-helix	trans	-65.1	-38.1	178.5	54.5	0	0	0	0	113	Q212 L213 F220 Y221 F384 A387 L388	Q212-T216 WeakPolarHBondContact O-CB 3.21Å; Q212-T216 VanDerWaalsContact O-CG2 3.26Å; Q212-T216 WeakPolarHBondContact O-CG2 3.22Å; Q212-T216 PolarHBondContact O-N 3.45Å; Q212-T216 PolarHBondContact O-OG1 3.37Å; L213-T216 PolarHBondContact O-OG1 2.8Å; T216-F220 PolarHBondContact O-N 3.08Å; T216-Y221 WeakPolarHBondContact O-CD2 3.46Å; T216-Y221 PolarHBondContact O-N 3.12Å; T216-F384 HydrophobicContact CG2-CD1 4.24Å; T216-A387 HydrophobicContact CG2-CB 3.89Å; T216-L388 VanDerWaalsContact OG1-CD2 3.23Å; T216-L388 WeakPolarHBondContact OG1-CD2 3.15Å
217	I	94.5	Very high	92.3	Very high	70 Å²	70	49.3 Å²	49.3	36%	0.359	25%	0.251	S	S	.	.	I	π-helix	trans	-63.2	-47	176.6	-71.6	168.4	0	0	0	111.2	L213 F214 S215 Y221 V222	L213-I217 WeakPolarHBondContact O-CB 3.26Å; L213-I217 WeakPolarHBondContact O-CD1 3.49Å; L213-I217 WeakPolarHBondContact O-CG1 3.45Å; L213-I217 PolarHBondContact O-N 3.29Å; F214-I217 PolarHBondContact O-N 3.4Å; S215-I217 PolarHBondContact O-N 3.5Å; I217-Y221 PolarHBondContact O-N 3.04Å; I217-V222 HydrophobicContact CG2-CG2 3.91Å; I217-V222 PolarHBondContact O-N 3.06Å
218	L	94.6	Very high	93	Very high	88 Å²	88	52.1 Å²	52.1	46%	0.461	27%	0.267	S	S	.	.	I	π-helix	trans	-73.2	-40.8	-179	-68.8	173	0	0	0	112.7	I180 F214 S215 P223	I180-L218 HydrophobicContact CD1-CB 4.12Å; I180-L218 HydrophobicContact CG1-CB 4.39Å; F214-L218 WeakPolarHBondContact O-CB 3.45Å; F214-L218 VanDerWaalsContact O-CG 3.29Å; F214-L218 WeakPolarHBondContact O-CG 3.11Å; F214-L218 PolarHBondContact O-N 3.06Å; S215-L218 PolarHBondContact O-N 2.95Å; L218-P223 VanDerWaalsContact O-CD 3.23Å; L218-P223 WeakPolarHBondContact O-CD 3.12Å
219	A	94.4	Very high	93.6	Very high	6 Å²	6	53.5 Å²	53.5	5%	0.05	27%	0.273	C	S	.	.	I	π-helix	trans	-70.3	-38.5	-178.5	0	0	0	0	0	112.7	I138 I180 S215	I138-A219 VanDerWaalsContact CG2-O 3.25Å; I138-A219 WeakPolarHBondContact CG2-O 3.47Å; I180-A219 HydrophobicContact CG2-CB 4.05Å; S215-A219 WeakPolarHBondContact O-CB 3.27Å; S215-A219 PolarHBondContact O-N 3.35Å
220	F	96.8	Very high	94.2	Very high	0 Å²	0	50.6 Å²	50.6	0%	0	26%	0.258	C	S	.	.	I	π-helix	trans	-124.8	-56.2	-170.9	-176.9	-103	0	0	0	114.5	I138 T216 V222 P223 L224 F376 W380 L381 F384	I138-F220 HydrophobicContact CD1-CD2 3.77Å; I138-F220 HydrophobicContact CD1-CE2 4.13Å; I138-F220 HydrophobicContact CD1-CG 4.49Å; T216-F220 PolarHBondContact O-N 3.08Å; F220-V222 PolarHBondContact O-N 3.49Å; F220-P223 WeakPolarHBondContact O-CD 3.32Å; F220-L224 HydrophobicContact CD1-CD2 4.39Å; F220-L224 HydrophobicContact CE1-CD2 3.73Å; F220-L224 HydrophobicContact CZ-CD2 4.09Å; F220-L224 WeakPolarHBondContact O-CB 3.41Å; F220-L224 PolarHBondContact O-N 3.42Å; F220-F376 HydrophobicContact CD2-CE1 4.19Å; F220-F376 HydrophobicContact CE2-CD1 4.5Å; F220-F376 AromaticContact CE2-CE1 3.92Å; F220-F376 HydrophobicContact CE2-CE1 3.92Å; F220-W380 HydrophobicContact CD2-CB 4.49Å; F220-W380 HydrophobicContact CE2-CB 3.75Å; F220-W380 HydrophobicContact CZ-CB 4.38Å; F220-L381 HydrophobicContact CE1-CD1 3.85Å; F220-L381 HydrophobicContact CZ-CB 4.15Å; F220-L381 HydrophobicContact CZ-CD1 4.24Å; F220-F384 HydrophobicContact CB-CB 4.5Å; F220-F384 HydrophobicContact CB-CD1 3.56Å; F220-F384 HydrophobicContact CB-CD2 3.81Å; F220-F384 HydrophobicContact CB-CE1 3.59Å; F220-F384 HydrophobicContact CB-CE2 3.83Å; F220-F384 HydrophobicContact CB-CG 3.68Å; F220-F384 HydrophobicContact CB-CZ 3.73Å; F220-F384 HydrophobicContact CD1-CB 3.53Å; F220-F384 HydrophobicContact CD1-CD1 4.21Å; F220-F384 AromaticContact CD1-CD2 3.73Å; F220-F384 HydrophobicContact CD1-CD2 3.73Å; F220-F384 AromaticContact CD1-CG 3.55Å; F220-F384 HydrophobicContact CD1-CG 3.55Å; F220-F384 AromaticContact CD2-CD2 3.24Å; F220-F384 HydrophobicContact CD2-CD2 3.24Å; F220-F384 AromaticContact CD2-CE2 3.36Å; F220-F384 HydrophobicContact CD2-CE2 3.36Å; F220-F384 AromaticContact CD2-CG 3.91Å; F220-F384 HydrophobicContact CD2-CG 3.91Å; F220-F384 HydrophobicContact CD2-CZ 4.11Å; F220-F384 HydrophobicContact CE1-CB 3.77Å; F220-F384 HydrophobicContact CE1-CD2 4.03Å; F220-F384 HydrophobicContact CE1-CG 4.08Å; F220-F384 AromaticContact CE2-CD2 3.59Å; F220-F384 HydrophobicContact CE2-CD2 3.59Å; F220-F384 AromaticContact CE2-CE2 3.98Å; F220-F384 HydrophobicContact CE2-CE2 3.98Å; F220-F384 HydrophobicContact CE2-CG 4.4Å; F220-F384 HydrophobicContact CG-CB 4Å; F220-F384 AromaticContact CG-CD1 3.9Å; F220-F384 HydrophobicContact CG-CD1 3.9Å; F220-F384 AromaticContact CG-CD2 3.31Å; F220-F384 HydrophobicContact CG-CD2 3.31Å; F220-F384 HydrophobicContact CG-CE1 4.22Å; F220-F384 AromaticContact CG-CE2 3.67Å; F220-F384 HydrophobicContact CG-CE2 3.67Å; F220-F384 AromaticContact CG-CG 3.44Å; F220-F384 HydrophobicContact CG-CG 3.44Å; F220-F384 VanDerWaalsContact CG-CG 3.44Å; F220-F384 HydrophobicContact CG-CZ 4.12Å; F220-F384 HydrophobicContact CZ-CB 4.41Å; F220-F384 AromaticContact CZ-CD2 3.97Å; F220-F384 HydrophobicContact CZ-CD2 3.97Å; F220-F384 HydrophobicContact CZ-CG 4.48Å
221	Y	97.2	Very high	94.5	Very high	54 Å²	54	47.4 Å²	47.4	21%	0.212	24%	0.24	C	C	.	.	I	π-helix	trans	-70	-36.8	-168	-68.9	-81.6	0	0	0	113.9	T216 I217 L224 L225 F384 V385 L388	T216-Y221 WeakPolarHBondContact O-CD2 3.46Å; T216-Y221 PolarHBondContact O-N 3.12Å; I217-Y221 PolarHBondContact O-N 3.04Å; Y221-L224 HydrophobicContact CD1-CD2 4.49Å; Y221-L225 WeakPolarHBondContact O-CB 3.45Å; Y221-L225 PolarHBondContact O-N 2.98Å; Y221-F384 HydrophobicContact CE2-CB 4.1Å; Y221-F384 PolarHBondContact OH-O 3.3Å; Y221-F384 VanDerWaalsContact OH-O 3.08Å; Y221-V385 PolarHBondContact OH-N 3.19Å; Y221-L388 HydrophobicContact CD2-CD1 4.3Å; Y221-L388 HydrophobicContact CE1-CD1 4.36Å; Y221-L388 HydrophobicContact CE2-CD1 3.47Å; Y221-L388 VanDerWaalsContact CE2-CD1 3.47Å; Y221-L388 HydrophobicContact CE2-CD2 4.39Å; Y221-L388 HydrophobicContact CE2-CG 3.82Å; Y221-L388 WeakPolarHBondContact OH-CD1 3.22Å
222	V	97.4	Very high	94.9	Very high	66 Å²	66	54.1 Å²	54.1	40%	0.4	27%	0.265	S	S	.	.	H	α-helix	trans	-67.3	-51.7	174.1	168.1	0	0	0	0	111.2	I217 F220 L224 L225 L226	I217-V222 HydrophobicContact CG2-CG2 3.91Å; I217-V222 PolarHBondContact O-N 3.06Å; F220-V222 PolarHBondContact O-N 3.49Å; V222-L224 VanDerWaalsContact C-N 3.3Å; V222-L224 PolarHBondContact O-N 3.5Å; V222-L225 PolarHBondContact O-N 3.34Å; V222-L226 HydrophobicContact CG1-CD1 4.35Å; V222-L226 WeakPolarHBondContact O-CG 3.37Å; V222-L226 PolarHBondContact O-N 3.44Å
223	P	97.8	Very high	95.2	Very high	3 Å²	3	60.5 Å²	60.5	2%	0.019	29%	0.288	C	S	.	.	H	α-helix	trans	-56.7	-38.6	171.6	-29.2	37.2	0	0	0	114.1	I138 L139 V142 L218 F220 L226 I227	I138-P223 HydrophobicContact CB-CB 4.39Å; I138-P223 HydrophobicContact CD1-CB 3.77Å; I138-P223 HydrophobicContact CG1-CB 3.73Å; I138-P223 HydrophobicContact CG2-CB 3.87Å; I138-P223 HydrophobicContact CG2-CG 4.19Å; L139-P223 HydrophobicContact CD2-CB 4.28Å; L139-P223 HydrophobicContact CD2-CG 3.85Å; L139-P223 HydrophobicContact CG-CG 4.49Å; V142-P223 HydrophobicContact CG2-CB 3.94Å; L218-P223 VanDerWaalsContact O-CD 3.23Å; L218-P223 WeakPolarHBondContact O-CD 3.12Å; F220-P223 WeakPolarHBondContact O-CD 3.32Å; P223-L226 PolarHBondContact O-N 2.94Å; P223-I227 WeakPolarHBondContact O-CB 3.41Å; P223-I227 VanDerWaalsContact O-CG1 3.32Å; P223-I227 WeakPolarHBondContact O-CG1 3.5Å; P223-I227 PolarHBondContact O-N 3.37Å
224	L	97.9	Very high	95.3	Very high	18 Å²	18	58.3 Å²	58.3	9%	0.094	28%	0.277	C	S	.	.	H	α-helix	trans	-61	-48.5	175.4	175.2	62.2	0	0	0	111.7	I138 F220 Y221 V222 L226 I227 L228 I377	I138-L224 HydrophobicContact CD1-CB 4.34Å; F220-L224 HydrophobicContact CD1-CD2 4.39Å; F220-L224 HydrophobicContact CE1-CD2 3.73Å; F220-L224 HydrophobicContact CZ-CD2 4.09Å; F220-L224 WeakPolarHBondContact O-CB 3.41Å; F220-L224 PolarHBondContact O-N 3.42Å; Y221-L224 HydrophobicContact CD1-CD2 4.49Å; V222-L224 VanDerWaalsContact C-N 3.3Å; V222-L224 PolarHBondContact O-N 3.5Å; L224-L226 VanDerWaalsContact C-N 3.33Å; L224-L226 PolarHBondContact O-N 3.1Å; L224-I227 WeakPolarHBondContact O-CB 3.42Å; L224-I227 PolarHBondContact O-N 3.13Å; L224-L228 HydrophobicContact CD1-CD1 4.15Å; L224-L228 HydrophobicContact CD1-CG 4.23Å; L224-L228 HydrophobicContact CG-CD1 4.13Å; L224-L228 VanDerWaalsContact O-CG 3.32Å; L224-L228 WeakPolarHBondContact O-CG 3.27Å; L224-L228 PolarHBondContact O-N 3.02Å; L224-I377 HydrophobicContact CD1-CD1 3.61Å; L224-I377 HydrophobicContact CD1-CG1 3.66Å; L224-I377 HydrophobicContact CD1-CG2 4.06Å
225	L	98	Very high	95.3	Very high	104 Å²	104	58.8 Å²	58.8	55%	0.545	28%	0.275	S	S	.	.	H	α-helix	trans	-59.6	-44.4	176.6	178.7	60.9	0	0	0	111.2	Y221 V222 I227 L228 L229	Y221-L225 WeakPolarHBondContact O-CB 3.45Å; Y221-L225 PolarHBondContact O-N 2.98Å; V222-L225 PolarHBondContact O-N 3.34Å; L225-I227 PolarHBondContact O-N 2.97Å; L225-L228 PolarHBondContact O-N 3.43Å; L225-L229 HydrophobicContact CD1-CD1 4.15Å; L225-L229 HydrophobicContact CD1-CG 4.23Å; L225-L229 HydrophobicContact CG-CD1 4.04Å; L225-L229 WeakPolarHBondContact O-CB 3.21Å; L225-L229 VanDerWaalsContact O-CG 3.27Å; L225-L229 WeakPolarHBondContact O-CG 3.32Å; L225-L229 PolarHBondContact O-N 3.01Å
226	L	97.7	Very high	95.4	Very high	78 Å²	78	60.3 Å²	60.3	41%	0.408	28%	0.284	S	S	.	.	H	α-helix	trans	-60.5	-45.1	175.9	-68.2	174.6	0	0	0	111.8	V142 V222 P223 L224 L229 L230	V142-L226 HydrophobicContact CG1-CB 4.4Å; V142-L226 HydrophobicContact CG2-CB 4.39Å; V222-L226 HydrophobicContact CG1-CD1 4.35Å; V222-L226 WeakPolarHBondContact O-CG 3.37Å; V222-L226 PolarHBondContact O-N 3.44Å; P223-L226 PolarHBondContact O-N 2.94Å; L224-L226 VanDerWaalsContact C-N 3.33Å; L224-L226 PolarHBondContact O-N 3.1Å; L226-L229 PolarHBondContact O-N 2.9Å; L226-L230 WeakPolarHBondContact O-CB 3.37Å; L226-L230 WeakPolarHBondContact O-CD1 3.38Å; L226-L230 WeakPolarHBondContact O-CG 3.27Å; L226-L230 PolarHBondContact O-N 3.3Å
227	I	96.5	Very high	95.3	Very high	1 Å²	1	61.6 Å²	61.6	1%	0.005	29%	0.292	C	S	.	.	H	α-helix	trans	-56.8	-50.5	174.8	-79.1	168.6	0	0	0	111	I138 L141 V142 P223 L224 L225 L229 L230 Y231 T373 I377	I138-I227 HydrophobicContact CD1-CD1 4.21Å; I138-I227 HydrophobicContact CG1-CD1 3.58Å; L141-I227 HydrophobicContact CB-CD1 3.77Å; V142-I227 HydrophobicContact CB-CG1 4.46Å; V142-I227 HydrophobicContact CG2-CD1 4.02Å; V142-I227 HydrophobicContact CG2-CG1 3.7Å; P223-I227 WeakPolarHBondContact O-CB 3.41Å; P223-I227 VanDerWaalsContact O-CG1 3.32Å; P223-I227 WeakPolarHBondContact O-CG1 3.5Å; P223-I227 PolarHBondContact O-N 3.37Å; L224-I227 WeakPolarHBondContact O-CB 3.42Å; L224-I227 PolarHBondContact O-N 3.13Å; L225-I227 PolarHBondContact O-N 2.97Å; I227-L229 PolarHBondContact O-N 3.3Å; I227-L230 PolarHBondContact O-N 3.14Å; I227-Y231 HydrophobicContact CG2-CD2 3.82Å; I227-Y231 HydrophobicContact CG2-CE2 4.08Å; I227-Y231 WeakPolarHBondContact O-CD2 3.36Å; I227-Y231 PolarHBondContact O-N 3.04Å; I227-T373 HydrophobicContact CD1-CG2 4.45Å; I227-T373 HydrophobicContact CG2-CG2 3.32Å; I227-I377 HydrophobicContact CG2-CD1 4.25Å
228	L	96.3	Very high	94.9	Very high	97 Å²	97	59.5 Å²	59.5	51%	0.508	29%	0.285	S	S	.	.	H	α-helix	trans	-61.7	-44.5	-178.7	-68.5	172	0	0	0	111.5	L224 L225 L230 Y231 W232 I377	L224-L228 HydrophobicContact CD1-CD1 4.15Å; L224-L228 HydrophobicContact CD1-CG 4.23Å; L224-L228 HydrophobicContact CG-CD1 4.13Å; L224-L228 VanDerWaalsContact O-CG 3.32Å; L224-L228 WeakPolarHBondContact O-CG 3.27Å; L224-L228 PolarHBondContact O-N 3.02Å; L225-L228 PolarHBondContact O-N 3.43Å; L228-L230 PolarHBondContact O-N 3.06Å; L228-Y231 PolarHBondContact O-N 3.17Å; L228-W232 VanDerWaalsContact O-CB 3.32Å; L228-W232 WeakPolarHBondContact O-CB 3.35Å; L228-W232 PolarHBondContact O-N 3.28Å; L228-I377 HydrophobicContact CD2-CD1 4.49Å
229	L	97.3	Very high	94.5	Very high	95 Å²	95	58.9 Å²	58.9	50%	0.497	28%	0.28	S	S	.	.	H	α-helix	trans	-62.8	-40.6	175.6	-69.7	172.3	0	0	0	112.3	L225 L226 I227 R233	L225-L229 HydrophobicContact CD1-CD1 4.15Å; L225-L229 HydrophobicContact CD1-CG 4.23Å; L225-L229 HydrophobicContact CG-CD1 4.04Å; L225-L229 WeakPolarHBondContact O-CB 3.21Å; L225-L229 VanDerWaalsContact O-CG 3.27Å; L225-L229 WeakPolarHBondContact O-CG 3.32Å; L225-L229 PolarHBondContact O-N 3.01Å; L226-L229 PolarHBondContact O-N 2.9Å; I227-L229 PolarHBondContact O-N 3.3Å; L229-R233 WeakPolarHBondContact O-CB 3.49Å; L229-R233 VanDerWaalsContact O-CG 3.25Å; L229-R233 WeakPolarHBondContact O-CG 3.47Å; L229-R233 PolarHBondContact O-N 2.85Å
230	L	96.4	Very high	94.2	Very high	23 Å²	23	62 Å²	62	12%	0.12	30%	0.296	C	S	.	.	H	α-helix	trans	-67.4	-45	177.7	-72.4	165.6	0	0	0	111.9	V142 A145 L146 Y149 L226 I227 L228 R233 I234	V142-L230 HydrophobicContact CG1-CD1 4.17Å; A145-L230 HydrophobicContact CB-CB 3.96Å; A145-L230 HydrophobicContact CB-CD1 3.9Å; L146-L230 HydrophobicContact CD2-CD1 4.04Å; L146-L230 HydrophobicContact CD2-CD2 3.61Å; L146-L230 HydrophobicContact CD2-CG 4.49Å; L146-L230 HydrophobicContact CG-CD1 3.79Å; L146-L230 HydrophobicContact CG-CD2 4.2Å; Y149-L230 HydrophobicContact CG-CD2 4.43Å; L226-L230 WeakPolarHBondContact O-CB 3.37Å; L226-L230 WeakPolarHBondContact O-CD1 3.38Å; L226-L230 WeakPolarHBondContact O-CG 3.27Å; L226-L230 PolarHBondContact O-N 3.3Å; I227-L230 PolarHBondContact O-N 3.14Å; L228-L230 PolarHBondContact O-N 3.06Å; L230-R233 PolarHBondContact O-N 2.76Å; L230-I234 WeakPolarHBondContact O-CB 3.49Å; L230-I234 VanDerWaalsContact O-CG1 3.25Å; L230-I234 WeakPolarHBondContact O-CG1 3.43Å; L230-I234 PolarHBondContact O-N 2.85Å
231	Y	93	Very high	93.6	Very high	45 Å²	45	64.1 Å²	64.1	18%	0.176	30%	0.304	C	S	.	.	H	α-helix	trans	-66.5	-36.9	176.1	-85.3	-72.7	0	0	0	112.6	A145 I227 L228 I234 Y235 L369 A370 T373	A145-Y231 HydrophobicContact CB-CD2 4.46Å; A145-Y231 HydrophobicContact CB-CE2 4.03Å; I227-Y231 HydrophobicContact CG2-CD2 3.82Å; I227-Y231 HydrophobicContact CG2-CE2 4.08Å; I227-Y231 WeakPolarHBondContact O-CD2 3.36Å; I227-Y231 PolarHBondContact O-N 3.04Å; L228-Y231 PolarHBondContact O-N 3.17Å; Y231-I234 HydrophobicContact CD1-CD1 4.22Å; Y231-I234 HydrophobicContact CE1-CD1 4.44Å; Y231-I234 PolarHBondContact O-N 3.09Å; Y231-Y235 WeakPolarHBondContact O-CB 3.48Å; Y231-Y235 PolarHBondContact O-N 2.73Å; Y231-L369 PolarHBondContact OH-O 2.88Å; Y231-L369 VanDerWaalsContact OH-O 3.14Å; Y231-A370 HydrophobicContact CD1-CB 4.35Å; Y231-A370 HydrophobicContact CE1-CB 3.77Å; Y231-A370 PolarHBondContact OH-N 2.79Å; Y231-T373 HydrophobicContact CD2-CG2 4.26Å; Y231-T373 HydrophobicContact CE2-CG2 3.65Å; Y231-T373 WeakPolarHBondContact CE2-OG1 3.41Å; Y231-T373 PolarHBondContact OH-OG1 3.4Å
232	W	94.7	Very high	92.9	Very high	162 Å²	162	64.7 Å²	64.7	61%	0.614	31%	0.31	S	S	*	.	H	α-helix	trans	-58.7	-48.8	169.9	176.7	-100.5	0	0	0	111.7	L228 I234 Y235 V236	L228-W232 VanDerWaalsContact O-CB 3.32Å; L228-W232 WeakPolarHBondContact O-CB 3.35Å; L228-W232 PolarHBondContact O-N 3.28Å; W232-I234 PolarHBondContact O-N 3.3Å; W232-Y235 WeakPolarHBondContact O-CB 3.23Å; W232-Y235 PolarHBondContact O-N 3.39Å; W232-V236 HydrophobicContact CD2-CG2 4.49Å; W232-V236 HydrophobicContact CZ2-CG2 4.42Å; W232-V236 WeakPolarHBondContact O-CG2 3.43Å; W232-V236 PolarHBondContact O-N 2.96Å
233	R	95	Very high	92.4	Very high	150 Å²	150	64.9 Å²	64.9	57%	0.566	31%	0.308	S	S	*	.	H	α-helix	trans	-63.4	-40.4	176.9	-70	-71.4	-174.4	178.2	1.6	112.3	Y149 L229 L230 V236 V237	Y149-R233 HydrophobicContact CD2-CB 3.93Å; Y149-R233 HydrophobicContact CE2-CB 3.72Å; L229-R233 WeakPolarHBondContact O-CB 3.49Å; L229-R233 VanDerWaalsContact O-CG 3.25Å; L229-R233 WeakPolarHBondContact O-CG 3.47Å; L229-R233 PolarHBondContact O-N 2.85Å; L230-R233 PolarHBondContact O-N 2.76Å; R233-V236 PolarHBondContact O-N 3.46Å; R233-V237 WeakPolarHBondContact O-CB 3.25Å; R233-V237 VanDerWaalsContact O-CG2 3.26Å; R233-V237 WeakPolarHBondContact O-CG2 3.23Å; R233-V237 PolarHBondContact O-N 3.46Å
234	I	91.5	Very high	91.8	Very high	14 Å²	14	73.2 Å²	73.2	7%	0.072	34%	0.339	C	S	.	.	H	α-helix	trans	-58.6	-47.7	172.9	-71.8	161.8	0	0	0	110.5	R148 Y149 V152 L230 Y231 W232 V237 A238	R148-I234 HydrophobicContact CB-CD1 3.9Å; Y149-I234 HydrophobicContact CD2-CG1 4.26Å; V152-I234 HydrophobicContact CG2-CG2 4.48Å; L230-I234 WeakPolarHBondContact O-CB 3.49Å; L230-I234 VanDerWaalsContact O-CG1 3.25Å; L230-I234 WeakPolarHBondContact O-CG1 3.43Å; L230-I234 PolarHBondContact O-N 2.85Å; Y231-I234 HydrophobicContact CD1-CD1 4.22Å; Y231-I234 HydrophobicContact CE1-CD1 4.44Å; Y231-I234 PolarHBondContact O-N 3.09Å; W232-I234 PolarHBondContact O-N 3.3Å; I234-V237 PolarHBondContact O-N 3.14Å; I234-A238 WeakPolarHBondContact O-CB 3.3Å; I234-A238 PolarHBondContact O-N 3.45Å
235	Y	90.8	Very high	91	Very high	142 Å²	142	75.5 Å²	75.5	56%	0.557	35%	0.349	S	S	*	.	H	α-helix	trans	-59.5	-51.7	178.5	171.3	-98.2	0	0	0	111.6	Y231 W232 V237 A238 H239	Y231-Y235 WeakPolarHBondContact O-CB 3.48Å; Y231-Y235 PolarHBondContact O-N 2.73Å; W232-Y235 WeakPolarHBondContact O-CB 3.23Å; W232-Y235 PolarHBondContact O-N 3.39Å; Y235-V237 PolarHBondContact O-N 3.33Å; Y235-A238 PolarHBondContact O-N 2.92Å; Y235-H239 WeakPolarHBondContact O-CB 3.48Å; Y235-H239 PolarHBondContact O-N 3.26Å
236	V	92.7	Very high	90.2	Very high	45 Å²	45	78.6 Å²	78.6	27%	0.273	35%	0.354	S	S	.	.	H	α-helix	trans	-58.5	-46.6	179.6	171.4	0	0	0	0	111.3	W232 R233 N240	W232-V236 HydrophobicContact CD2-CG2 4.49Å; W232-V236 HydrophobicContact CZ2-CG2 4.42Å; W232-V236 WeakPolarHBondContact O-CG2 3.43Å; W232-V236 PolarHBondContact O-N 2.96Å; R233-V236 PolarHBondContact O-N 3.46Å; V236-N240 VanDerWaalsContact O-CB 3.28Å; V236-N240 WeakPolarHBondContact O-CB 3.3Å; V236-N240 PolarHBondContact O-N 2.9Å; V236-N240 PolarHBondContact O-ND2 3.25Å
237	V	90.3	Very high	89.5	Confident	33 Å²	33	81.9 Å²	81.9	20%	0.2	37%	0.365	C	S	.	.	H	α-helix	trans	-66.8	-43.9	179.9	173.9	0	0	0	0	111.7	Y149 V152 R233 I234 Y235 N240 R241	Y149-V237 HydrophobicContact CE2-CG2 4.29Å; V152-V237 HydrophobicContact CG1-CB 4.26Å; V152-V237 HydrophobicContact CG1-CG1 3.9Å; V152-V237 VanDerWaalsContact O-CG1 3.25Å; V152-V237 WeakPolarHBondContact O-CG1 3.47Å; R233-V237 WeakPolarHBondContact O-CB 3.25Å; R233-V237 VanDerWaalsContact O-CG2 3.26Å; R233-V237 WeakPolarHBondContact O-CG2 3.23Å; R233-V237 PolarHBondContact O-N 3.46Å; I234-V237 PolarHBondContact O-N 3.14Å; Y235-V237 PolarHBondContact O-N 3.33Å; V237-N240 PolarHBondContact O-N 3.27Å; V237-R241 WeakPolarHBondContact O-CG 3.48Å; V237-R241 PolarHBondContact O-N 3.36Å
238	A	86.4	Confident	88.8	Confident	25 Å²	25	88.8 Å²	88.8	21%	0.207	39%	0.39	C	S	.	.	H	α-helix	trans	-64.2	-43.6	177.5	0	0	0	0	0	111.8	V152 I234 Y235 R241 I242	V152-A238 HydrophobicContact CG1-CB 4.09Å; I234-A238 WeakPolarHBondContact O-CB 3.3Å; I234-A238 PolarHBondContact O-N 3.45Å; Y235-A238 PolarHBondContact O-N 2.92Å; A238-R241 PolarHBondContact O-N 3.04Å; A238-I242 VanDerWaalsContact O-CG1 3.32Å; A238-I242 WeakPolarHBondContact O-CG1 3.38Å; A238-I242 PolarHBondContact O-N 3.27Å
239	H	86.9	Confident	87.9	Confident	76 Å²	76	90.6 Å²	90.6	35%	0.352	39%	0.394	S	S	.	.	H	α-helix	trans	-61.2	-48.3	176.4	-176.2	-109.7	0	0	0	111.4	Y235 R241 I242 L243	Y235-H239 WeakPolarHBondContact O-CB 3.48Å; Y235-H239 PolarHBondContact O-N 3.26Å; H239-R241 VanDerWaalsContact C-N 3.29Å; H239-R241 PolarHBondContact O-N 3.37Å; H239-I242 PolarHBondContact O-N 2.99Å; H239-I242 VanDerWaalsContact O-N 3.14Å; H239-L243 VanDerWaalsContact CE1-CD1 3.44Å; H239-L243 WeakPolarHBondContact CE1-CD1 3.45Å; H239-L243 WeakPolarHBondContact O-CG 3.31Å; H239-L243 PolarHBondContact O-N 3.39Å
240	N	88.6	Confident	86.8	Confident	72 Å²	72	89.4 Å²	89.4	39%	0.385	39%	0.394	S	S	.	.	H	α-helix	trans	-62.2	-35.1	177.9	-72.2	-14.9	0	0	0	112.5	V236 V237 R244	V236-N240 VanDerWaalsContact O-CB 3.28Å; V236-N240 WeakPolarHBondContact O-CB 3.3Å; V236-N240 PolarHBondContact O-N 2.9Å; V236-N240 PolarHBondContact O-ND2 3.25Å; V237-N240 PolarHBondContact O-N 3.27Å; N240-R244 WeakPolarHBondContact O-CB 3.39Å; N240-R244 VanDerWaalsContact O-CG 3.24Å; N240-R244 WeakPolarHBondContact O-CG 3.36Å; N240-R244 PolarHBondContact O-N 3.47Å
241	R	83.1	Confident	85.6	Confident	44 Å²	44	96.7 Å²	96.7	17%	0.166	42%	0.421	C	S	.	.	H	α-helix	trans	-65.4	-47.4	171.6	-75.9	177.1	171	-148.3	5.2	112	V152 A153 V237 A238 H239 L243 R244 E245	V152-R241 PolarHBondContact O-NE 3.44Å; V152-R241 PolarHBondContact O-NH1 3.07Å; V152-R241 PolarHBondContact O-NH2 3.38Å; A153-R241 PolarHBondContact O-NH2 2.88Å; V237-R241 WeakPolarHBondContact O-CG 3.48Å; V237-R241 PolarHBondContact O-N 3.36Å; A238-R241 PolarHBondContact O-N 3.04Å; H239-R241 VanDerWaalsContact C-N 3.29Å; H239-R241 PolarHBondContact O-N 3.37Å; R241-L243 VanDerWaalsContact C-N 3.31Å; R241-L243 PolarHBondContact O-N 3.47Å; R241-R244 PolarHBondContact O-N 2.96Å; R241-E245 WeakPolarHBondContact O-CG 3.26Å; R241-E245 PolarHBondContact O-N 3.27Å
242	I	81.7	Confident	84.4	Confident	66 Å²	66	98 Å²	98	34%	0.338	44%	0.437	S	S	.	.	H	α-helix	trans	-60.4	-40.5	177	-67.6	163.8	0	0	0	111.2	A238 H239 E245 R246	A238-I242 VanDerWaalsContact O-CG1 3.32Å; A238-I242 WeakPolarHBondContact O-CG1 3.38Å; A238-I242 PolarHBondContact O-N 3.27Å; H239-I242 PolarHBondContact O-N 2.99Å; H239-I242 VanDerWaalsContact O-N 3.14Å; I242-E245 PolarHBondContact O-N 3.09Å; I242-R246 WeakPolarHBondContact O-CG 3.43Å; I242-R246 PolarHBondContact O-N 3.32Å
243	L	87.2	Confident	82.9	Confident	69 Å²	69	96.1 Å²	96.1	36%	0.361	44%	0.437	S	S	.	.	H	α-helix	trans	-65.5	-42.1	175	-71.2	-176	0	0	0	112.5	H239 R241 R246 K247	H239-L243 VanDerWaalsContact CE1-CD1 3.44Å; H239-L243 WeakPolarHBondContact CE1-CD1 3.45Å; H239-L243 WeakPolarHBondContact O-CG 3.31Å; H239-L243 PolarHBondContact O-N 3.39Å; R241-L243 VanDerWaalsContact C-N 3.31Å; R241-L243 PolarHBondContact O-N 3.47Å; L243-R246 PolarHBondContact O-N 2.74Å; L243-K247 PolarHBondContact O-N 3.29Å
244	R	86	Confident	81.3	Confident	179 Å²	179	92.8 Å²	92.8	68%	0.675	44%	0.437	S	S	*	.	H	α-helix	trans	-63.3	-42	175.2	-73.8	171.5	-177.5	-165	0.5	111.8	N240 R241 K247 R248	N240-R244 WeakPolarHBondContact O-CB 3.39Å; N240-R244 VanDerWaalsContact O-CG 3.24Å; N240-R244 WeakPolarHBondContact O-CG 3.36Å; N240-R244 PolarHBondContact O-N 3.47Å; R241-R244 PolarHBondContact O-N 2.96Å; R244-K247 PolarHBondContact O-N 3.01Å; R244-R248 WeakPolarHBondContact O-CG 3.47Å; R244-R248 PolarHBondContact O-N 2.98Å
245	E	81.4	Confident	79.8	Confident	66 Å²	66	96 Å²	96	31%	0.308	47%	0.466	S	S	.	.	H	α-helix	trans	-61.9	-40.6	173.7	-73.7	178.8	-163.1	0	0	112.1	R241 I242 K249 A357 L358	R241-E245 WeakPolarHBondContact O-CG 3.26Å; R241-E245 PolarHBondContact O-N 3.27Å; I242-E245 PolarHBondContact O-N 3.09Å; E245-K249 WeakPolarHBondContact O-CG 3.36Å; E245-K249 PolarHBondContact O-N 2.98Å; E245-K249 VanDerWaalsContact O-N 3.15Å; E245-A357 WeakPolarHBondContact OE1-CA 3.39Å; E245-L358 PolarHBondContact OE1-N 3.17Å
246	R	81.7	Confident	78.1	Confident	169 Å²	169	96.5 Å²	96.5	64%	0.638	48%	0.478	S	S	*	.	H	α-helix	trans	-65.4	-47.8	174.5	-73.1	177.2	-171.4	-169.3	4.7	112.3	I242 L243 R248 K249 S250	I242-R246 WeakPolarHBondContact O-CG 3.43Å; I242-R246 PolarHBondContact O-N 3.32Å; L243-R246 PolarHBondContact O-N 2.74Å; R246-R248 PolarHBondContact O-N 2.94Å; R246-K249 PolarHBondContact O-N 2.96Å; R246-S250 PolarHBondContact O-N 2.95Å
247	K	83.1	Confident	75.9	Confident	147 Å²	147	96.9 Å²	96.9	64%	0.639	49%	0.491	S	S	*	.	H	α-helix	trans	-58.9	-45.1	178.1	-75.8	-168.7	175.6	-167.7	0	111.7	L243 R244 K249 S250 Y251	L243-K247 PolarHBondContact O-N 3.29Å; R244-K247 PolarHBondContact O-N 3.01Å; K247-K249 PolarHBondContact O-N 3.46Å; K247-S250 WeakPolarHBondContact O-CB 3.41Å; K247-S250 PolarHBondContact O-N 3.19Å; K247-S250 VanDerWaalsContact O-N 3.12Å; K247-Y251 VanDerWaalsContact O-CD2 3.28Å; K247-Y251 WeakPolarHBondContact O-CD2 3.45Å; K247-Y251 PolarHBondContact O-N 2.83Å
248	R	80	Confident	73.2	Confident	145 Å²	145	103.6 Å²	103.6	55%	0.547	52%	0.52	S	S	.	.	H	α-helix	trans	-62	-40.3	177	-75.1	-177.1	177.9	174.2	1.2	113.2	R244 R246 S250 Y251 S252 S355	R244-R248 WeakPolarHBondContact O-CG 3.47Å; R244-R248 PolarHBondContact O-N 2.98Å; R246-R248 PolarHBondContact O-N 2.94Å; R248-S250 VanDerWaalsContact C-N 3.29Å; R248-S250 PolarHBondContact O-N 2.86Å; R248-Y251 PolarHBondContact O-N 3.44Å; R248-S252 PolarHBondContact O-N 3.01Å; R248-S252 PolarHBondContact O-OG 3.29Å; R248-S355 PolarHBondContact NH1-OG 3.02Å
249	K	77.9	Confident	70.9	Confident	136 Å²	136	106.8 Å²	106.8	59%	0.591	54%	0.539	S	S	*	.	H	α-helix	trans	-64.8	-32.5	173.5	-73.7	177.6	179.6	-177	0	112.9	E245 R246 K247 S252 I253	E245-K249 WeakPolarHBondContact O-CG 3.36Å; E245-K249 PolarHBondContact O-N 2.98Å; E245-K249 VanDerWaalsContact O-N 3.15Å; R246-K249 PolarHBondContact O-N 2.96Å; K247-K249 PolarHBondContact O-N 3.46Å; K249-S252 WeakPolarHBondContact CA-OG 3.28Å; K249-S252 PolarHBondContact O-OG 2.87Å; K249-I253 WeakPolarHBondContact O-CD1 3.37Å; K249-I253 VanDerWaalsContact O-CG1 3.24Å; K249-I253 WeakPolarHBondContact O-CG1 3.32Å; K249-I253 PolarHBondContact O-N 2.71Å
250	S	74.8	Confident	68.2	Low	70 Å²	70	107.4 Å²	107.4	49%	0.49	55%	0.552	S	S	.	*	H	α-helix	trans	-67.3	-48.5	173	-153.1	0	0	0	0	111.1	R246 K247 R248 S252 I253 S254	R246-S250 PolarHBondContact O-N 2.95Å; K247-S250 WeakPolarHBondContact O-CB 3.41Å; K247-S250 PolarHBondContact O-N 3.19Å; K247-S250 VanDerWaalsContact O-N 3.12Å; R248-S250 VanDerWaalsContact C-N 3.29Å; R248-S250 PolarHBondContact O-N 2.86Å; S250-S252 VanDerWaalsContact C-N 3.35Å; S250-S252 PolarHBondContact O-N 3.28Å; S250-I253 PolarHBondContact O-N 2.86Å; S250-I253 VanDerWaalsContact O-N 3.08Å; S250-S254 PolarHBondContact O-N 3.42Å; S250-S254 PolarHBondContact O-OG 3.28Å
251	Y	72	Confident	65.7	Low	175 Å²	175	114.7 Å²	114.7	69%	0.686	57%	0.574	S	S	*	*	H	α-helix	trans	-61.7	-39	177.6	-80.2	-67.4	0	0	0	113	K247 R248 I253 S254 A255	K247-Y251 VanDerWaalsContact O-CD2 3.28Å; K247-Y251 WeakPolarHBondContact O-CD2 3.45Å; K247-Y251 PolarHBondContact O-N 2.83Å; R248-Y251 PolarHBondContact O-N 3.44Å; Y251-I253 PolarHBondContact O-N 2.94Å; Y251-S254 PolarHBondContact O-N 2.97Å; Y251-A255 VanDerWaalsContact O-CB 3.31Å; Y251-A255 WeakPolarHBondContact O-CB 3.37Å; Y251-A255 PolarHBondContact O-N 3.41Å
252	S	66.8	Low	63.4	Low	72 Å²	72	120.7 Å²	120.7	50%	0.503	60%	0.604	S	S	.	*	H	α-helix	trans	-68.3	-21.2	175.3	61.2	0	0	0	0	113.8	R248 K249 S250	R248-S252 PolarHBondContact O-N 3.01Å; R248-S252 PolarHBondContact O-OG 3.29Å; K249-S252 WeakPolarHBondContact CA-OG 3.28Å; K249-S252 PolarHBondContact O-OG 2.87Å; S250-S252 VanDerWaalsContact C-N 3.35Å; S250-S252 PolarHBondContact O-N 3.28Å
253	I	64	Low	61.4	Low	123 Å²	123	122.8 Å²	122.8	63%	0.631	62%	0.62	S	S	*	*	H	α-helix	trans	-85.3	-38	174	-68.9	166.6	0	0	0	110.4	K249 S250 Y251 G257	K249-I253 WeakPolarHBondContact O-CD1 3.37Å; K249-I253 VanDerWaalsContact O-CG1 3.24Å; K249-I253 WeakPolarHBondContact O-CG1 3.32Å; K249-I253 PolarHBondContact O-N 2.71Å; S250-I253 PolarHBondContact O-N 2.86Å; S250-I253 VanDerWaalsContact O-N 3.08Å; Y251-I253 PolarHBondContact O-N 2.94Å; I253-G257 PolarHBondContact O-N 2.94Å
254	S	61.5	Low	59.1	Low	81 Å²	81	127.2 Å²	127.2	57%	0.566	64%	0.639	S	S	*	*	H	α-helix	trans	-73.3	-31.7	178	-60.4	0	0	0	0	113.6	S250 Y251 D256 G257	S250-S254 PolarHBondContact O-N 3.42Å; S250-S254 PolarHBondContact O-OG 3.28Å; Y251-S254 PolarHBondContact O-N 2.97Å; S254-D256 VanDerWaalsContact C-N 3.32Å; S254-G257 PolarHBondContact O-N 3.45Å
255	A	58.2	Low	56.8	Low	82 Å²	82	123.6 Å²	123.6	68%	0.678	64%	0.641	S	S	*	*	G	3₁₀ helix	trans	-71.6	-26.9	176.3	0	0	0	0	0	113.1	Y251	Y251-A255 VanDerWaalsContact O-CB 3.31Å; Y251-A255 WeakPolarHBondContact O-CB 3.37Å; Y251-A255 PolarHBondContact O-N 3.41Å
256	D	56.1	Low	54.6	Low	152 Å²	152	126 Å²	126	81%	0.813	66%	0.664	S	S	*	*	G	3₁₀ helix	trans	-83.9	-0.3	174.3	-142.8	24.3	0	0	0	111.7	S254	S254-D256 VanDerWaalsContact C-N 3.32Å
257	G	47.1	Very low	52.6	Low	52 Å²	52	125.6 Å²	125.6	54%	0.536	67%	0.674	S	S	.	*	G	3₁₀ helix	trans	-104.9	9.4	-170	0	0	0	0	0	115.7	I253 S254 P259	I253-G257 PolarHBondContact O-N 2.94Å; S254-G257 PolarHBondContact O-N 3.45Å; G257-P259 WeakPolarHBondContact O-CD 3.43Å
258	Q	33.9	Very low	50.2	Low	174 Å²	174	126.5 Å²	126.5	81%	0.813	68%	0.684	S	S	*	*			trans	-90.9	107.6	164	-89.3	-178.4	-84.1	0	0	108.8	S260	Q258-S260 PolarHBondContact O-N 2.99Å
259	P	36.3	Very low	48.1	Very low	92 Å²	92	128.9 Å²	128.9	60%	0.597	70%	0.702	S	S	*	*			trans	-72.6	118	170.6	3	13.7	0	0	0	107.7	G257 W261	G257-P259 WeakPolarHBondContact O-CD 3.43Å; P259-W261 VanDerWaalsContact C-N 3.29Å; P259-W261 PolarHBondContact O-N 2.9Å
260	S	31.9	Very low	45.9	Very low	89 Å²	89	127.8 Å²	127.8	62%	0.622	71%	0.711	S	S	*	*			trans	-74.7	85.7	170.4	50	0	0	0	0	109.5	Q258 Q262	Q258-S260 PolarHBondContact O-N 2.99Å; S260-Q262 PolarHBondContact O-N 2.97Å
261	W	34.5	Very low	43.9	Very low	225 Å²	225	130.5 Å²	130.5	85%	0.852	73%	0.73	S	S	*	*	T	Hydrogen-bonded Turn	trans	-66.5	30.6	173	-71.4	103.1	0	0	0	113.7	P259	P259-W261 VanDerWaalsContact C-N 3.29Å; P259-W261 PolarHBondContact O-N 2.9Å
262	Q	35.9	Very low	42.2	Very low	171 Å²	171	128.2 Å²	128.2	80%	0.799	74%	0.735	S	S	*	*	T	Hydrogen-bonded Turn	trans	-127.7	10	-171.1	-69.1	-174.1	-57	0	0	113.6	S260	S260-Q262 PolarHBondContact O-N 2.97Å
263	T	40.3	Very low	40.6	Very low	109 Å²	109	132.1 Å²	132.1	67%	0.669	75%	0.75	S	S	*	*	S	Bend	trans	-118.2	-4.7	-174.1	-23.9	0	0	0	0	115
264	E	38.3	Very low	39.1	Very low	162 Å²	162	135.7 Å²	135.7	76%	0.757	76%	0.761	S	S	*	*	S	Bend	trans	-107.5	-3	177.7	-73.7	-172.6	126	0	0	114.4	C266	E264-C266 PolarHBondContact O-N 3.3Å
265	S	37.9	Very low	37.8	Very low	103 Å²	103	136.5 Å²	136.5	72%	0.72	76%	0.764	S	S	*	*	T	Hydrogen-bonded Turn	trans	-73.6	7.7	-179.6	55.5	0	0	0	0	115.3
266	C	35.4	Very low	36.6	Very low	117 Å²	117	141.3 Å²	141.3	79%	0.791	77%	0.772	S	S	*	*	T	Hydrogen-bonded Turn	trans	-113.2	6.6	-180	-70.3	0	0	0	0	114.6	E264	E264-C266 PolarHBondContact O-N 3.3Å
267	L	39.1	Very low	35.5	Very low	161 Å²	161	142 Å²	142	84%	0.843	77%	0.771	S	S	*	*	S	Bend	trans	-126.2	10.4	-178.3	-68.1	176.6	0	0	0	114.6
268	L	33.2	Very low	34.7	Very low	166 Å²	166	142.2 Å²	142.2	87%	0.869	77%	0.774	S	S	*	*			trans	-103.8	54.8	179.8	-93.4	164.9	0	0	0	112.6
269	E	34.7	Very low	34.3	Very low	194 Å²	194	138.4 Å²	138.4	91%	0.907	77%	0.766	S	S	*	*	S	Bend	trans	-144.5	47.6	174.9	-155.8	163.8	-143.3	0	0	113.5
270	S	33.1	Very low	34.1	Very low	114 Å²	114	144.1 Å²	144.1	80%	0.797	78%	0.777	S	S	*	*			trans	-171.8	93.7	151.6	-171.7	0	0	0	0	111.9
271	S	31.3	Very low	33.8	Very low	127 Å²	127	144.6 Å²	144.6	89%	0.888	79%	0.786	S	S	*	*			trans	-168.7	89.2	158.9	-86.4	0	0	0	0	111.4
272	T	36.1	Very low	33.7	Very low	127 Å²	127	142.1 Å²	142.1	78%	0.779	79%	0.789	S	S	*	*			trans	-92.9	132	162.3	43.5	0	0	0	0	110.3
273	N	33.5	Very low	33.3	Very low	154 Å²	154	140 Å²	140	82%	0.824	79%	0.788	S	S	*	*			trans	116.8	64.4	161.7	-55.5	-13.5	0	0	0	117.7
274	K	33.6	Very low	32.8	Very low	198 Å²	198	139.8 Å²	139.8	86%	0.861	79%	0.791	S	S	*	*				9.7	158	115.1	-110.7	-166.7	-177.7	-175.9	0	119.5
275	P	34.4	Very low	32.6	Very low	97 Å²	97	138.4 Å²	138.4	63%	0.63	79%	0.793	S	S	*	*				-138.2	-174.8	-64.6	41.1	-22.9	0	0	0	113.4
276	E	31.8	Very low	32.4	Very low	183 Å²	183	139.8 Å²	139.8	86%	0.855	79%	0.792	S	S	*	*			trans	139.7	153.7	156.1	-82	155.4	-142.8	0	0	111.4
277	E	32.4	Very low	32.4	Very low	166 Å²	166	139.4 Å²	139.4	78%	0.776	78%	0.783	S	S	*	*			cis	-149.7	176	-6.3	-149.5	-77.7	102.9	0	0	108
278	G	31.8	Very low	32.2	Very low	58 Å²	58	139.6 Å²	139.6	60%	0.598	78%	0.777	S	S	*	*			trans	120.6	113.4	148	0	0	0	0	0	116.5
279	S	25.6	Very low	32.3	Very low	93 Å²	93	139.2 Å²	139.2	65%	0.65	78%	0.776	S	S	*	*			trans	-105.7	-168.2	176.5	-167.1	0	0	0	0	113
280	Y	31	Very low	32.1	Very low	212 Å²	212	135.8 Å²	135.8	83%	0.831	77%	0.768	S	S	*	*			trans	114.8	127.8	155.3	-48.6	-55	0	0	0	117.8
281	A	26.9	Very low	32	Very low	99 Å²	99	139.7 Å²	139.7	82%	0.818	77%	0.774	S	S	*	*			trans	-124.3	161.9	174.9	0	0	0	0	0	110.1
282	L	30.6	Very low	31.9	Very low	173 Å²	173	139.8 Å²	139.8	91%	0.906	77%	0.769	S	S	*	*			trans	-133.7	155.4	177.8	-143.2	85.9	0	0	0	113.2
283	T	27.8	Very low	31.8	Very low	127 Å²	127	141.7 Å²	141.7	78%	0.779	77%	0.773	S	S	*	*			trans	-132	170.8	-156.9	39.6	0	0	0	0	115
284	S	29.8	Very low	31.8	Very low	104 Å²	104	140.2 Å²	140.2	73%	0.727	77%	0.772	S	S	*	*			trans	80.9	152.6	155.1	-141.6	0	0	0	0	116.8
285	V	35.6	Very low	31.6	Very low	133 Å²	133	138.8 Å²	138.8	81%	0.806	77%	0.772	S	S	*	*			cis	-152.8	166	45	171	0	0	0	0	113
286	N	33.7	Very low	31.4	Very low	132 Å²	132	145.7 Å²	145.7	71%	0.706	79%	0.786	S	S	*	*			trans	-90.8	-157.2	-173.8	-48.8	-50.1	0	0	0	114
287	D	35.4	Very low	31.6	Very low	110 Å²	110	146.6 Å²	146.6	59%	0.588	79%	0.787	S	S	*	*			cis	-166.9	161	17.9	-137.2	-6.7	0	0	0	115.7
288	K	33.9	Very low	31.5	Very low	165 Å²	165	148.3 Å²	148.3	72%	0.717	79%	0.788	S	S	*	*			trans	24.7	146.2	147.5	-67.7	158.4	-160.6	141.7	0	122.8
289	N	34.5	Very low	31.9	Very low	158 Å²	158	150.8 Å²	150.8	85%	0.845	79%	0.792	S	S	*	*				-172.2	174.1	59.9	-145	-0.5	0	0	0	114.1
290	T	31.1	Very low	32.8	Very low	122 Å²	122	151.6 Å²	151.6	75%	0.748	80%	0.797	S	S	*	*			trans	-136	147.6	-173	-60.4	0	0	0	0	114.2
291	Q	30.5	Very low	33.3	Very low	196 Å²	196	147.3 Å²	147.3	92%	0.916	79%	0.788	S	S	*	*			trans	-152.6	154.9	164.7	-109	177.7	7	0	0	113.6
292	T	30.9	Very low	34.4	Very low	129 Å²	129	144.1 Å²	144.1	79%	0.791	76%	0.76	S	S	*	*			trans	-134.9	141.4	-166.5	41.7	0	0	0	0	113.9
293	I	33.6	Very low	35	Very low	167 Å²	167	142.5 Å²	142.5	86%	0.856	75%	0.751	S	S	*	*			trans	-143.6	146.9	175.3	-65	-173.1	0	0	0	109.7
294	P	32.2	Very low	35.9	Very low	123 Å²	123	144 Å²	144	80%	0.799	75%	0.749	S	S	*	*			trans	-103.3	174.8	-149.4	39.3	-36.9	0	0	0	119
295	L	29.7	Very low	36.8	Very low	167 Å²	167	143.9 Å²	143.9	87%	0.874	74%	0.737	S	S	*	*			trans	-69.2	147.1	-176.1	-84.5	79.7	0	0	0	115.7
296	R	31.6	Very low	37.4	Very low	243 Å²	243	139.5 Å²	139.5	92%	0.917	72%	0.715	S	S	*	*			trans	-140.7	131.1	159.7	-153.9	174.1	-159.3	177.5	6	113.7
297	K	34.1	Very low	38.1	Very low	201 Å²	201	135.6 Å²	135.6	87%	0.874	70%	0.701	S	S	*	*			trans	11.5	134.5	169	-73.7	-177	171.9	-178	0	122
298	Y	31.5	Very low	39.3	Very low	203 Å²	203	133.3 Å²	133.3	80%	0.796	69%	0.694	S	S	*	*			trans	-76	144.4	172.7	-74.2	-113.8	0	0	0	113.4	S302	Y298-S302 WeakPolarHBondContact CD1-OG 3.41Å
299	T	40.8	Very low	40.5	Very low	110 Å²	110	133.6 Å²	133.6	68%	0.675	69%	0.69	S	S	*	*			trans	-128.3	161	158.5	51.5	0	0	0	0	109.9	L301 S302	T299-L301 VanDerWaalsContact C-N 3.28Å; T299-L301 PolarHBondContact O-N 3.12Å; T299-L301 VanDerWaalsContact O-N 3.1Å; T299-S302 VanDerWaalsContact O-CB 3.26Å; T299-S302 WeakPolarHBondContact O-CB 3.46Å; T299-S302 PolarHBondContact O-N 3.11Å; T299-S302 PolarHBondContact O-OG 2.9Å
300	S	44	Very low	41.6	Very low	110 Å²	110	133.4 Å²	133.4	77%	0.769	68%	0.682	S	S	*	*	T	Hydrogen-bonded Turn	trans	-59	-25.8	-164.7	45.2	0	0	0	0	116.3	S302 L303	S300-S302 PolarHBondContact O-N 3.43Å; S300-L303 PolarHBondContact O-N 2.98Å; S300-L303 VanDerWaalsContact O-N 3.08Å
301	L	41.5	Very low	43	Very low	121 Å²	121	132.4 Å²	132.4	63%	0.634	68%	0.675	S	S	*	*	H	α-helix	trans	-52.9	-34.8	170.5	-108	71.5	0	0	0	112.4	T299 L303 Q304 E305	T299-L301 VanDerWaalsContact C-N 3.28Å; T299-L301 PolarHBondContact O-N 3.12Å; T299-L301 VanDerWaalsContact O-N 3.1Å; L301-L303 PolarHBondContact O-N 2.94Å; L301-L303 VanDerWaalsContact O-N 3.13Å; L301-Q304 PolarHBondContact O-N 3.2Å; L301-Q304 VanDerWaalsContact O-N 3.13Å; L301-E305 PolarHBondContact O-N 2.97Å
302	S	49.2	Very low	44.5	Very low	33 Å²	33	129 Å²	129	23%	0.231	66%	0.659	C	S	.	*	H	α-helix	trans	-61.5	-20.7	-180	66.2	0	0	0	0	113.9	Y298 T299 S300 A306	Y298-S302 WeakPolarHBondContact CD1-OG 3.41Å; T299-S302 VanDerWaalsContact O-CB 3.26Å; T299-S302 WeakPolarHBondContact O-CB 3.46Å; T299-S302 PolarHBondContact O-N 3.11Å; T299-S302 PolarHBondContact O-OG 2.9Å; S300-S302 PolarHBondContact O-N 3.43Å; S302-A306 WeakPolarHBondContact O-CA 3.43Å; S302-A306 WeakPolarHBondContact O-CB 3.38Å; S302-A306 PolarHBondContact O-N 3.29Å
303	L	43.4	Very low	46	Very low	139 Å²	139	127.1 Å²	127.1	73%	0.728	64%	0.644	S	S	*	*	H	α-helix	trans	-75.4	-39	176.3	-141.7	85.4	0	0	0	111.6	S300 L301 A306 A307	S300-L303 PolarHBondContact O-N 2.98Å; S300-L303 VanDerWaalsContact O-N 3.08Å; L301-L303 PolarHBondContact O-N 2.94Å; L301-L303 VanDerWaalsContact O-N 3.13Å; L303-A306 PolarHBondContact O-N 2.9Å; L303-A307 WeakPolarHBondContact O-CB 3.43Å; L303-A307 PolarHBondContact O-N 3.43Å
304	Q	46.4	Very low	47.4	Very low	158 Å²	158	123.4 Å²	123.4	74%	0.738	63%	0.629	S	S	*	*	H	α-helix	trans	-75.3	-37.8	177.6	-165.1	170	-8.3	0	0	110.8	L301 A307 S308	L301-Q304 PolarHBondContact O-N 3.2Å; L301-Q304 VanDerWaalsContact O-N 3.13Å; Q304-A307 PolarHBondContact O-N 2.95Å; Q304-S308 WeakPolarHBondContact O-CB 3.49Å; Q304-S308 PolarHBondContact O-N 3.35Å
305	E	48.7	Very low	48.9	Very low	102 Å²	102	124.9 Å²	124.9	48%	0.477	62%	0.623	S	S	.	*	H	α-helix	trans	-66.9	-37.8	168.5	-67.7	-168.9	163.7	0	0	112.7	L301 S308 R309	L301-E305 PolarHBondContact O-N 2.97Å; E305-S308 PolarHBondContact O-N 3.27Å; E305-R309 WeakPolarHBondContact O-CB 3.5Å; E305-R309 VanDerWaalsContact O-CG 3.26Å; E305-R309 WeakPolarHBondContact O-CG 3.39Å; E305-R309 PolarHBondContact O-N 3.4Å
306	A	48.5	Very low	50.5	Low	40 Å²	40	126.9 Å²	126.9	33%	0.331	62%	0.619	S	S	.	*	H	α-helix	trans	-69.5	-34.7	174.8	0	0	0	0	0	112	S302 L303 K310	S302-A306 WeakPolarHBondContact O-CA 3.43Å; S302-A306 WeakPolarHBondContact O-CB 3.38Å; S302-A306 PolarHBondContact O-N 3.29Å; L303-A306 PolarHBondContact O-N 2.9Å; A306-K310 VanDerWaalsContact O-CB 3.29Å; A306-K310 WeakPolarHBondContact O-CB 3.34Å; A306-K310 VanDerWaalsContact O-CG 3.25Å; A306-K310 WeakPolarHBondContact O-CG 3.42Å; A306-K310 PolarHBondContact O-N 3.41Å
307	A	48.5	Very low	52.2	Low	51 Å²	51	123.5 Å²	123.5	42%	0.421	61%	0.606	S	S	.	*	H	α-helix	trans	-63.2	-48.6	169.9	0	0	0	0	0	110.7	L303 Q304 R309 K310 V311	L303-A307 WeakPolarHBondContact O-CB 3.43Å; L303-A307 PolarHBondContact O-N 3.43Å; Q304-A307 PolarHBondContact O-N 2.95Å; A307-R309 PolarHBondContact O-N 3.39Å; A307-K310 PolarHBondContact O-N 2.91Å; A307-V311 WeakPolarHBondContact O-CG2 3.44Å; A307-V311 PolarHBondContact O-N 3.5Å
308	S	60.7	Low	53.6	Low	62 Å²	62	117.5 Å²	117.5	43%	0.434	59%	0.586	S	S	.	*	H	α-helix	trans	-59.7	-45.4	175.5	-174	0	0	0	0	112.4	Q304 E305 K310 V311 Q312	Q304-S308 WeakPolarHBondContact O-CB 3.49Å; Q304-S308 PolarHBondContact O-N 3.35Å; E305-S308 PolarHBondContact O-N 3.27Å; S308-K310 PolarHBondContact O-N 3.21Å; S308-V311 PolarHBondContact O-N 3.31Å; S308-Q312 WeakPolarHBondContact O-CB 3.36Å; S308-Q312 WeakPolarHBondContact O-CG 3.29Å; S308-Q312 PolarHBondContact O-N 2.98Å
309	R	58.4	Low	55.3	Low	171 Å²	171	114 Å²	114	65%	0.645	58%	0.577	S	S	*	*	H	α-helix	trans	-63.1	-39.4	173.9	-73.1	178.5	-169.8	-159.2	6.7	112	E305 A307 Q312 L313	E305-R309 WeakPolarHBondContact O-CB 3.5Å; E305-R309 VanDerWaalsContact O-CG 3.26Å; E305-R309 WeakPolarHBondContact O-CG 3.39Å; E305-R309 PolarHBondContact O-N 3.4Å; A307-R309 PolarHBondContact O-N 3.39Å; R309-Q312 PolarHBondContact O-N 3.3Å; R309-L313 WeakPolarHBondContact O-CB 3.4Å; R309-L313 PolarHBondContact O-N 2.93Å
310	K	58.9	Low	56.4	Low	154 Å²	154	112 Å²	112	67%	0.67	57%	0.567	S	S	*	*	H	α-helix	trans	-63.6	-43.3	173.2	-79.8	175.5	179.9	179.4	0	111.3	A306 A307 S308 L313 V314	A306-K310 VanDerWaalsContact O-CB 3.29Å; A306-K310 WeakPolarHBondContact O-CB 3.34Å; A306-K310 VanDerWaalsContact O-CG 3.25Å; A306-K310 WeakPolarHBondContact O-CG 3.42Å; A306-K310 PolarHBondContact O-N 3.41Å; A307-K310 PolarHBondContact O-N 2.91Å; S308-K310 PolarHBondContact O-N 3.21Å; K310-L313 PolarHBondContact O-N 2.92Å; K310-V314 WeakPolarHBondContact O-CG2 3.47Å; K310-V314 PolarHBondContact O-N 3.09Å
311	V	59.2	Low	57.4	Low	100 Å²	100	111.8 Å²	111.8	61%	0.606	56%	0.557	S	S	*	*	H	α-helix	trans	-63.1	-46.2	175	170.4	0	0	0	0	111.1	A307 S308 L313 V314 F315	A307-V311 WeakPolarHBondContact O-CG2 3.44Å; A307-V311 PolarHBondContact O-N 3.5Å; S308-V311 PolarHBondContact O-N 3.31Å; V311-L313 VanDerWaalsContact C-N 3.31Å; V311-L313 PolarHBondContact O-N 3.4Å; V311-V314 PolarHBondContact O-N 3Å; V311-F315 WeakPolarHBondContact O-CB 3.37Å; V311-F315 PolarHBondContact O-N 2.98Å
312	Q	62.9	Low	58.5	Low	124 Å²	124	109.7 Å²	109.7	58%	0.579	55%	0.549	S	S	*	.	H	α-helix	trans	-62.2	-35.8	173.8	-74.2	-173.4	-4.4	0	0	112.7	S308 R309 F315 R316	S308-Q312 WeakPolarHBondContact O-CB 3.36Å; S308-Q312 WeakPolarHBondContact O-CG 3.29Å; S308-Q312 PolarHBondContact O-N 2.98Å; R309-Q312 PolarHBondContact O-N 3.3Å; Q312-F315 PolarHBondContact O-N 2.96Å; Q312-R316 WeakPolarHBondContact O-CB 3.18Å; Q312-R316 PolarHBondContact O-N 3.49Å
313	L	62.9	Low	59.2	Low	91 Å²	91	115 Å²	115	48%	0.476	57%	0.565	S	S	.	*	H	α-helix	trans	-72.5	-36.1	177.8	-162.7	154.1	0	0	0	111.2	R309 K310 V311 R317	R309-L313 WeakPolarHBondContact O-CB 3.4Å; R309-L313 PolarHBondContact O-N 2.93Å; K310-L313 PolarHBondContact O-N 2.92Å; V311-L313 VanDerWaalsContact C-N 3.31Å; V311-L313 PolarHBondContact O-N 3.4Å; L313-R317 HydrophobicContact CD2-CG 4.22Å; L313-R317 WeakPolarHBondContact O-CB 3.46Å; L313-R317 WeakPolarHBondContact O-CG 3.4Å; L313-R317 PolarHBondContact O-N 3.03Å
314	V	62.7	Low	60.4	Low	88 Å²	88	114 Å²	114	53%	0.533	56%	0.558	S	S	.	*	H	α-helix	trans	-61.5	-47.2	166.3	170.3	0	0	0	0	110.2	K310 V311 R316 R317 V318	K310-V314 WeakPolarHBondContact O-CG2 3.47Å; K310-V314 PolarHBondContact O-N 3.09Å; V311-V314 PolarHBondContact O-N 3Å; V314-R316 PolarHBondContact O-N 2.98Å; V314-R317 CarbonylContact O-C 3.57Å; V314-R317 PolarHBondContact O-N 3.34Å; V314-R317 VanDerWaalsContact O-N 3.17Å; V314-V318 HydrophobicContact CG1-CG2 4.31Å; V314-V318 WeakPolarHBondContact O-CB 3.38Å; V314-V318 WeakPolarHBondContact O-CG2 3.3Å; V314-V318 PolarHBondContact O-N 2.92Å
315	F	64.2	Low	61.5	Low	155 Å²	155	111 Å²	111	68%	0.68	55%	0.547	S	S	*	.	H	α-helix	trans	-63.3	-43.2	179.5	-154.9	-90.6	0	0	0	112.2	V311 Q312 V318 H319	V311-F315 WeakPolarHBondContact O-CB 3.37Å; V311-F315 PolarHBondContact O-N 2.98Å; Q312-F315 PolarHBondContact O-N 2.96Å; F315-V318 PolarHBondContact O-N 3.29Å; F315-H319 WeakPolarHBondContact O-CB 3.28Å; F315-H319 PolarHBondContact O-N 2.71Å
316	R	62.7	Low	62.6	Low	208 Å²	208	108.1 Å²	108.1	79%	0.785	54%	0.535	S	S	*	.	H	α-helix	trans	-61.7	-41.3	171.2	-95.4	-175.1	166.1	-177.6	-3.3	112.2	Q312 V314 H319 S320	Q312-R316 WeakPolarHBondContact O-CB 3.18Å; Q312-R316 PolarHBondContact O-N 3.49Å; V314-R316 PolarHBondContact O-N 2.98Å; R316-H319 PolarHBondContact O-N 3.17Å; R316-S320 WeakPolarHBondContact O-CB 3.28Å; R316-S320 PolarHBondContact O-N 3.03Å
317	R	66.2	Low	63.7	Low	173 Å²	173	109.6 Å²	109.6	65%	0.653	54%	0.537	S	S	*	.	H	α-helix	trans	-65	-40.4	174.3	-80.8	-179.1	174.6	179	-0.5	111.8	L313 V314 L321	L313-R317 HydrophobicContact CD2-CG 4.22Å; L313-R317 WeakPolarHBondContact O-CB 3.46Å; L313-R317 WeakPolarHBondContact O-CG 3.4Å; L313-R317 PolarHBondContact O-N 3.03Å; V314-R317 CarbonylContact O-C 3.57Å; V314-R317 PolarHBondContact O-N 3.34Å; V314-R317 VanDerWaalsContact O-N 3.17Å; R317-L321 VanDerWaalsContact O-CB 3.23Å; R317-L321 WeakPolarHBondContact O-CB 3.19Å; R317-L321 WeakPolarHBondContact O-CG 3.29Å; R317-L321 PolarHBondContact O-N 3.48Å
318	V	64.8	Low	65	Low	75 Å²	75	114.6 Å²	114.6	46%	0.455	55%	0.549	S	S	.	.	H	α-helix	trans	-66.7	-41.9	175.4	170.2	0	0	0	0	111.2	V314 F315 L321 T322	V314-V318 HydrophobicContact CG1-CG2 4.31Å; V314-V318 WeakPolarHBondContact O-CB 3.38Å; V314-V318 WeakPolarHBondContact O-CG2 3.3Å; V314-V318 PolarHBondContact O-N 2.92Å; F315-V318 PolarHBondContact O-N 3.29Å; V318-L321 PolarHBondContact O-N 3.03Å; V318-T322 VanDerWaalsContact O-CB 3.3Å; V318-T322 WeakPolarHBondContact O-CB 3.48Å; V318-T322 PolarHBondContact O-N 3Å; V318-T322 PolarHBondContact O-OG1 3.08Å
319	H	65.9	Low	65.7	Low	129 Å²	129	115.6 Å²	115.6	60%	0.597	55%	0.546	S	S	*	.	H	α-helix	trans	-66.1	-45.2	175.7	-169.7	-96.2	0	0	0	111.5	F315 R316 T322 Y323	F315-H319 WeakPolarHBondContact O-CB 3.28Å; F315-H319 PolarHBondContact O-N 2.71Å; R316-H319 PolarHBondContact O-N 3.17Å; H319-T322 PolarHBondContact O-N 3.49Å; H319-T322 VanDerWaalsContact O-N 3.16Å; H319-Y323 WeakPolarHBondContact O-CB 3.48Å; H319-Y323 PolarHBondContact O-N 2.9Å
320	S	65.3	Low	66.3	Low	68 Å²	68	114.9 Å²	114.9	48%	0.476	54%	0.543	S	S	.	.	H	α-helix	trans	-60.2	-46.1	173.4	178.3	0	0	0	0	111.8	R316 T322 Y323 M324	R316-S320 WeakPolarHBondContact O-CB 3.28Å; R316-S320 PolarHBondContact O-N 3.03Å; S320-T322 VanDerWaalsContact C-N 3.31Å; S320-T322 PolarHBondContact O-N 3.38Å; S320-Y323 PolarHBondContact O-N 3.25Å; S320-M324 VanDerWaalsContact O-CB 3.24Å; S320-M324 WeakPolarHBondContact O-CB 3.35Å; S320-M324 WeakPolarHBondContact O-CG 3.43Å; S320-M324 PolarHBondContact O-N 3.49Å
321	L	64	Low	67	Low	105 Å²	105	116.4 Å²	116.4	55%	0.55	55%	0.545	S	S	.	.	H	α-helix	trans	-59.5	-40.6	172.4	-88	158.5	0	0	0	111.9	R317 V318 L325	R317-L321 VanDerWaalsContact O-CB 3.23Å; R317-L321 WeakPolarHBondContact O-CB 3.19Å; R317-L321 WeakPolarHBondContact O-CG 3.29Å; R317-L321 PolarHBondContact O-N 3.48Å; V318-L321 PolarHBondContact O-N 3.03Å; L321-L325 WeakPolarHBondContact O-CB 3.27Å; L321-L325 WeakPolarHBondContact O-CD1 3.16Å; L321-L325 WeakPolarHBondContact O-CG 3.39Å; L321-L325 PolarHBondContact O-N 3.44Å
322	T	66	Low	67.6	Low	77 Å²	77	113 Å²	113	47%	0.472	53%	0.525	S	S	.	.	H	α-helix	trans	-67.8	-42.1	179	-58.6	0	0	0	0	111.3	V318 H319 S320 L325 D326	V318-T322 VanDerWaalsContact O-CB 3.3Å; V318-T322 WeakPolarHBondContact O-CB 3.48Å; V318-T322 PolarHBondContact O-N 3Å; V318-T322 PolarHBondContact O-OG1 3.08Å; H319-T322 PolarHBondContact O-N 3.49Å; H319-T322 VanDerWaalsContact O-N 3.16Å; S320-T322 VanDerWaalsContact C-N 3.31Å; S320-T322 PolarHBondContact O-N 3.38Å; T322-L325 PolarHBondContact O-N 3.08Å; T322-D326 PolarHBondContact O-N 3.49Å
323	Y	63.4	Low	67.9	Low	145 Å²	145	114.4 Å²	114.4	57%	0.569	53%	0.525	S	S	*	.	H	α-helix	trans	-65.1	-47.2	174.3	-176.3	-101.9	0	0	0	111.8	H319 S320 L325 D326 L327	H319-Y323 WeakPolarHBondContact O-CB 3.48Å; H319-Y323 PolarHBondContact O-N 2.9Å; S320-Y323 PolarHBondContact O-N 3.25Å; Y323-L325 VanDerWaalsContact C-N 3.29Å; Y323-L325 PolarHBondContact O-N 2.85Å; Y323-D326 PolarHBondContact O-N 3.05Å; Y323-D326 VanDerWaalsContact O-N 3.11Å; Y323-L327 HydrophobicContact CD1-CD1 3.89Å; Y323-L327 HydrophobicContact CD1-CG 4.29Å; Y323-L327 HydrophobicContact CE1-CD1 3.39Å; Y323-L327 HydrophobicContact CE1-CG 3.95Å; Y323-L327 PolarHBondContact O-N 2.68Å
324	M	67.4	Low	68.2	Low	117 Å²	117	118.6 Å²	118.6	58%	0.576	54%	0.535	S	S	*	.	H	α-helix	trans	-60	-36.7	173.3	-74.1	-73.2	-80.1	0	0	112.2	S320 K328	S320-M324 VanDerWaalsContact O-CB 3.24Å; S320-M324 WeakPolarHBondContact O-CB 3.35Å; S320-M324 WeakPolarHBondContact O-CG 3.43Å; S320-M324 PolarHBondContact O-N 3.49Å; M324-K328 WeakPolarHBondContact O-CB 3.27Å; M324-K328 PolarHBondContact O-N 2.87Å
325	L	70.8	Confident	68.6	Low	95 Å²	95	118.6 Å²	118.6	50%	0.497	53%	0.529	S	S	.	.	H	α-helix	trans	-70.2	-35.7	174	-76.3	167.7	0	0	0	112.2	L321 T322 Y323 K329	L321-L325 WeakPolarHBondContact O-CB 3.27Å; L321-L325 WeakPolarHBondContact O-CD1 3.16Å; L321-L325 WeakPolarHBondContact O-CG 3.39Å; L321-L325 PolarHBondContact O-N 3.44Å; T322-L325 PolarHBondContact O-N 3.08Å; Y323-L325 VanDerWaalsContact C-N 3.29Å; Y323-L325 PolarHBondContact O-N 2.85Å; L325-K329 WeakPolarHBondContact O-CB 3.4Å; L325-K329 PolarHBondContact O-N 3.24Å
326	D	71.5	Confident	68.8	Low	43 Å²	43	115.9 Å²	115.9	23%	0.23	52%	0.518	C	S	.	.	H	α-helix	trans	-72.2	-41.1	172.7	-160.1	63.6	0	0	0	111.8	T322 Y323 K328 K329 R330	T322-D326 PolarHBondContact O-N 3.49Å; Y323-D326 PolarHBondContact O-N 3.05Å; Y323-D326 VanDerWaalsContact O-N 3.11Å; D326-K328 PolarHBondContact O-N 3.48Å; D326-K329 CarbonylContact O-C 3.47Å; D326-K329 WeakPolarHBondContact O-CA 3.2Å; D326-K329 WeakPolarHBondContact O-CB 3.35Å; D326-K329 PolarHBondContact O-N 2.98Å; D326-K329 VanDerWaalsContact O-N 3.17Å; D326-K329 IonicContact OD1-NZ 3.96Å; D326-K329 PolarHBondContact OD1-NZ 2.84Å; D326-R330 WeakPolarHBondContact O-CG 3.33Å; D326-R330 PolarHBondContact O-N 3.4Å; D326-R330 IonicContact OD2-CZ 2.81Å; D326-R330 IonicContact OD2-NE 3.08Å; D326-R330 PolarHBondContact OD2-NE 3.45Å; D326-R330 IonicContact OD2-NH2 3.41Å; D326-R330 PolarHBondContact OD2-NH2 3.43Å; D326-R330 VanDerWaalsContact OD2-NH2 3.08Å
327	L	71.8	Confident	68.8	Low	71 Å²	71	111.9 Å²	111.9	37%	0.372	51%	0.512	S	S	.	.	H	α-helix	trans	-58.5	-47.4	171.7	-74.7	-176.4	0	0	0	111.7	Y323 K329 R330 R331	Y323-L327 HydrophobicContact CD1-CD1 3.89Å; Y323-L327 HydrophobicContact CD1-CG 4.29Å; Y323-L327 HydrophobicContact CE1-CD1 3.39Å; Y323-L327 HydrophobicContact CE1-CG 3.95Å; Y323-L327 PolarHBondContact O-N 2.68Å; L327-K329 VanDerWaalsContact C-N 3.28Å; L327-K329 PolarHBondContact O-N 2.95Å; L327-R330 WeakPolarHBondContact O-CB 3.26Å; L327-R330 PolarHBondContact O-N 3.49Å; L327-R330 VanDerWaalsContact O-N 3.1Å; L327-R331 PolarHBondContact O-N 2.99Å
328	K	74.8	Confident	68.8	Low	155 Å²	155	108.5 Å²	108.5	67%	0.674	50%	0.504	S	S	*	.	H	α-helix	trans	-65.3	-32	176.7	-165.4	167.4	-170.6	167	0	112.3	M324 D326 S332	M324-K328 WeakPolarHBondContact O-CB 3.27Å; M324-K328 PolarHBondContact O-N 2.87Å; D326-K328 PolarHBondContact O-N 3.48Å; K328-S332 VanDerWaalsContact O-CB 3.23Å; K328-S332 WeakPolarHBondContact O-CB 3.23Å; K328-S332 PolarHBondContact O-N 2.96Å
329	K	75.5	Confident	68.7	Low	84 Å²	84	111.9 Å²	111.9	37%	0.365	51%	0.512	S	S	.	.	H	α-helix	trans	-73.3	-27.7	172.1	171	-174.9	157.2	-139.2	0	112.8	L325 D326 L327 R333	L325-K329 WeakPolarHBondContact O-CB 3.4Å; L325-K329 PolarHBondContact O-N 3.24Å; D326-K329 CarbonylContact O-C 3.47Å; D326-K329 WeakPolarHBondContact O-CA 3.2Å; D326-K329 WeakPolarHBondContact O-CB 3.35Å; D326-K329 PolarHBondContact O-N 2.98Å; D326-K329 VanDerWaalsContact O-N 3.17Å; D326-K329 IonicContact OD1-NZ 3.96Å; D326-K329 PolarHBondContact OD1-NZ 2.84Å; L327-K329 VanDerWaalsContact C-N 3.28Å; L327-K329 PolarHBondContact O-N 2.95Å; K329-R333 WeakPolarHBondContact O-CB 3.33Å; K329-R333 PolarHBondContact O-N 3.37Å
330	R	71	Confident	68.2	Low	155 Å²	155	112.8 Å²	112.8	59%	0.585	51%	0.514	S	S	*	.	H	α-helix	trans	-74.1	-50.8	169.9	-71.2	176.3	-165.9	-145.4	3.4	110.4	D326 L327 S332 R333 R334	D326-R330 WeakPolarHBondContact O-CG 3.33Å; D326-R330 PolarHBondContact O-N 3.4Å; D326-R330 IonicContact OD2-CZ 2.81Å; D326-R330 IonicContact OD2-NE 3.08Å; D326-R330 PolarHBondContact OD2-NE 3.45Å; D326-R330 IonicContact OD2-NH2 3.41Å; D326-R330 PolarHBondContact OD2-NH2 3.43Å; D326-R330 VanDerWaalsContact OD2-NH2 3.08Å; L327-R330 WeakPolarHBondContact O-CB 3.26Å; L327-R330 PolarHBondContact O-N 3.49Å; L327-R330 VanDerWaalsContact O-N 3.1Å; R330-S332 PolarHBondContact O-N 3.5Å; R330-R333 CarbonylContact O-C 3.58Å; R330-R333 WeakPolarHBondContact O-CA 3.36Å; R330-R333 WeakPolarHBondContact O-CB 3.17Å; R330-R333 PolarHBondContact O-N 2.97Å; R330-R334 PolarHBondContact O-N 2.03Å
331	R	73.6	Confident	67.7	Low	187 Å²	187	114.9 Å²	114.9	71%	0.706	52%	0.524	S	S	*	.	H	α-helix	trans	-55.9	-50.8	177.3	-158.3	-175.2	-170	153.6	4.1	111.4	L327 R333 R334 E335	L327-R331 PolarHBondContact O-N 2.99Å; R331-R333 PolarHBondContact O-N 2.96Å; R331-R333 VanDerWaalsContact O-N 3.17Å; R331-R334 WeakPolarHBondContact O-CA 3.29Å; R331-R334 WeakPolarHBondContact O-CB 3.38Å; R331-R334 PolarHBondContact O-N 3.36Å; R331-E335 WeakPolarHBondContact CG-OE1 3.31Å; R331-E335 IonicContact NE-OE1 3.98Å; R331-E335 WeakPolarHBondContact O-CG 3.31Å; R331-E335 PolarHBondContact O-N 2.9Å
332	S	72.6	Confident	66.9	Low	29 Å²	29	113.2 Å²	113.2	20%	0.203	52%	0.522	C	S	.	.	H	α-helix	trans	-65	-19.8	175.9	-176	0	0	0	0	114.2	K328 R330 E335 E336 K360	K328-S332 VanDerWaalsContact O-CB 3.23Å; K328-S332 WeakPolarHBondContact O-CB 3.23Å; K328-S332 PolarHBondContact O-N 2.96Å; R330-S332 PolarHBondContact O-N 3.5Å; S332-E335 WeakPolarHBondContact CA-OE2 3.45Å; S332-E336 WeakPolarHBondContact O-CB 3.48Å; S332-E336 PolarHBondContact O-N 2.9Å; S332-K360 PolarHBondContact OG-NZ 2.76Å
333	R	69.5	Low	66.2	Low	152 Å²	152	113.7 Å²	113.7	57%	0.574	52%	0.524	S	S	*	.	H	α-helix	trans	-83.1	-30.5	172.1	-151.2	-169.5	-47.6	-174	12.2	111.8	K329 R330 R331 L337	K329-R333 WeakPolarHBondContact O-CB 3.33Å; K329-R333 PolarHBondContact O-N 3.37Å; R330-R333 CarbonylContact O-C 3.58Å; R330-R333 WeakPolarHBondContact O-CA 3.36Å; R330-R333 WeakPolarHBondContact O-CB 3.17Å; R330-R333 PolarHBondContact O-N 2.97Å; R331-R333 PolarHBondContact O-N 2.96Å; R331-R333 VanDerWaalsContact O-N 3.17Å; R333-L337 WeakPolarHBondContact O-CB 3.13Å; R333-L337 PolarHBondContact O-N 3.37Å; R333-L337 VanDerWaalsContact O-N 3.09Å
334	R	69.2	Low	65.1	Low	179 Å²	179	112.6 Å²	112.6	68%	0.675	54%	0.536	S	S	*	.	H	α-helix	trans	-68.8	-49.3	171.1	-160.3	-170.2	-108.6	-170.8	-6.3	110	R330 R331 E336 L337 E338	R330-R334 PolarHBondContact O-N 2.03Å; R331-R334 WeakPolarHBondContact O-CA 3.29Å; R331-R334 WeakPolarHBondContact O-CB 3.38Å; R331-R334 PolarHBondContact O-N 3.36Å; R334-E336 VanDerWaalsContact C-N 3.27Å; R334-E336 PolarHBondContact O-N 2.91Å; R334-L337 CarbonylContact O-C 3.59Å; R334-L337 WeakPolarHBondContact O-CA 3.4Å; R334-L337 WeakPolarHBondContact O-CB 3.44Å; R334-L337 PolarHBondContact O-N 2.9Å; R334-E338 VanDerWaalsContact CD-OE1 3.32Å; R334-E338 WeakPolarHBondContact CD-OE1 3.34Å; R334-E338 VanDerWaalsContact CG-OE1 3.29Å; R334-E338 WeakPolarHBondContact CG-OE1 3.37Å; R334-E338 WeakPolarHBondContact O-CB 3.11Å; R334-E338 WeakPolarHBondContact O-CG 3.35Å; R334-E338 PolarHBondContact O-N 2.66Å
335	E	71.6	Confident	63.8	Low	88 Å²	88	111.7 Å²	111.7	41%	0.411	54%	0.542	S	S	.	.	H	α-helix	trans	-55.6	-37.8	172.8	-67.7	161.3	-163	0	0	112.8	R331 S332 E338 K339	R331-E335 WeakPolarHBondContact CG-OE1 3.31Å; R331-E335 IonicContact NE-OE1 3.98Å; R331-E335 WeakPolarHBondContact O-CG 3.31Å; R331-E335 PolarHBondContact O-N 2.9Å; S332-E335 WeakPolarHBondContact CA-OE2 3.45Å; E335-E338 WeakPolarHBondContact CA-OE2 3.44Å; E335-K339 WeakPolarHBondContact O-CB 3.41Å; E335-K339 WeakPolarHBondContact O-CG 3.07Å; E335-K339 PolarHBondContact O-N 2.7Å
336	E	66.9	Low	62.5	Low	99 Å²	99	112.6 Å²	112.6	46%	0.463	55%	0.551	S	S	.	*	H	α-helix	trans	-76.8	-23.2	177.5	-168.4	175.7	155.1	0	0	112.7	S332 R334 K340 K360	S332-E336 WeakPolarHBondContact O-CB 3.48Å; S332-E336 PolarHBondContact O-N 2.9Å; R334-E336 VanDerWaalsContact C-N 3.27Å; R334-E336 PolarHBondContact O-N 2.91Å; E336-K340 WeakPolarHBondContact O-CB 3.41Å; E336-K340 VanDerWaalsContact O-CG 3.29Å; E336-K340 WeakPolarHBondContact O-CG 3.34Å; E336-K340 PolarHBondContact O-N 2.8Å; E336-K360 IonicContact OE2-NZ 3.52Å
337	L	63.8	Low	60.8	Low	124 Å²	124	114.8 Å²	114.8	65%	0.649	58%	0.575	S	S	*	*	H	α-helix	trans	-78.5	-47.9	171.5	-154.2	77.4	0	0	0	110.4	R333 R334 K339 K340 T341	R333-L337 WeakPolarHBondContact O-CB 3.13Å; R333-L337 PolarHBondContact O-N 3.37Å; R333-L337 VanDerWaalsContact O-N 3.09Å; R334-L337 CarbonylContact O-C 3.59Å; R334-L337 WeakPolarHBondContact O-CA 3.4Å; R334-L337 WeakPolarHBondContact O-CB 3.44Å; R334-L337 PolarHBondContact O-N 2.9Å; L337-K339 PolarHBondContact O-N 3.06Å; L337-K340 CarbonylContact O-C 3.59Å; L337-K340 WeakPolarHBondContact O-CA 3.44Å; L337-K340 WeakPolarHBondContact O-CB 3.47Å; L337-K340 PolarHBondContact O-N 3.12Å; L337-T341 PolarHBondContact O-N 3.21Å; L337-T341 PolarHBondContact O-OG1 2.65Å; L337-T341 VanDerWaalsContact O-OG1 3.04Å
338	E	64.9	Low	59	Low	102 Å²	102	117.1 Å²	117.1	48%	0.477	59%	0.592	S	S	.	*	H	α-helix	trans	-57.6	-44.5	175.5	-71.6	159.9	176.5	0	0	111.5	R334 E335 K340 T341 S342	R334-E338 VanDerWaalsContact CD-OE1 3.32Å; R334-E338 WeakPolarHBondContact CD-OE1 3.34Å; R334-E338 VanDerWaalsContact CG-OE1 3.29Å; R334-E338 WeakPolarHBondContact CG-OE1 3.37Å; R334-E338 WeakPolarHBondContact O-CB 3.11Å; R334-E338 WeakPolarHBondContact O-CG 3.35Å; R334-E338 PolarHBondContact O-N 2.66Å; E335-E338 WeakPolarHBondContact CA-OE2 3.44Å; E338-K340 VanDerWaalsContact C-N 3.32Å; E338-K340 PolarHBondContact O-N 3.28Å; E338-T341 WeakPolarHBondContact CA-OG1 3.21Å; E338-T341 PolarHBondContact O-N 2.88Å; E338-T341 PolarHBondContact O-OG1 2.79Å; E338-T341 VanDerWaalsContact O-OG1 3.1Å; E338-S342 PolarHBondContact O-N 3.27Å
339	K	62.8	Low	57.2	Low	145 Å²	145	116 Å²	116	63%	0.63	60%	0.599	S	S	*	*	H	α-helix	trans	-67.3	-29.5	172.6	-76.5	-166.2	173	-157.6	0	113.3	E335 L337 T341 V343	E335-K339 WeakPolarHBondContact O-CB 3.41Å; E335-K339 WeakPolarHBondContact O-CG 3.07Å; E335-K339 PolarHBondContact O-N 2.7Å; L337-K339 PolarHBondContact O-N 3.06Å; K339-T341 VanDerWaalsContact C-N 3.34Å; K339-V343 HydrophobicContact CB-CG2 4.45Å; K339-V343 WeakPolarHBondContact O-CB 3.36Å; K339-V343 WeakPolarHBondContact O-CG2 3.33Å; K339-V343 PolarHBondContact O-N 3.37Å
340	K	55.2	Low	55.5	Low	148 Å²	148	117.7 Å²	117.7	64%	0.643	62%	0.621	S	S	*	*	H	α-helix	trans	-72.9	-26.4	173.7	-81.2	-179.9	179.8	-174.4	0	112.9	E336 L337 E338	E336-K340 WeakPolarHBondContact O-CB 3.41Å; E336-K340 VanDerWaalsContact O-CG 3.29Å; E336-K340 WeakPolarHBondContact O-CG 3.34Å; E336-K340 PolarHBondContact O-N 2.8Å; L337-K340 CarbonylContact O-C 3.59Å; L337-K340 WeakPolarHBondContact O-CA 3.44Å; L337-K340 WeakPolarHBondContact O-CB 3.47Å; L337-K340 PolarHBondContact O-N 3.12Å; E338-K340 VanDerWaalsContact C-N 3.32Å; E338-K340 PolarHBondContact O-N 3.28Å
341	T	55.2	Low	53.7	Low	112 Å²	112	114.8 Å²	114.8	69%	0.687	64%	0.639	S	S	*	*	H	α-helix	trans	-80.1	-35.1	169.1	21.4	0	0	0	0	112.9	L337 E338 K339	L337-T341 PolarHBondContact O-N 3.21Å; L337-T341 PolarHBondContact O-OG1 2.65Å; L337-T341 VanDerWaalsContact O-OG1 3.04Å; E338-T341 WeakPolarHBondContact CA-OG1 3.21Å; E338-T341 PolarHBondContact O-N 2.88Å; E338-T341 PolarHBondContact O-OG1 2.79Å; E338-T341 VanDerWaalsContact O-OG1 3.1Å; K339-T341 VanDerWaalsContact C-N 3.34Å
342	S	48.4	Very low	51.7	Low	71 Å²	71	108.7 Å²	108.7	50%	0.497	63%	0.634	S	S	.	*	H	α-helix	trans	-87.2	-19	-177.2	91.3	0	0	0	0	115.6	E338 S345	E338-S342 PolarHBondContact O-N 3.27Å; S342-S345 PolarHBondContact O-OG 3.37Å
343	V	49.8	Very low	49.8	Very low	86 Å²	86	113.1 Å²	113.1	52%	0.521	67%	0.666	S	S	.	*	G	3₁₀ helix	trans	-87.9	-6	-177.9	174.2	0	0	0	0	112.6	K339 S345	K339-V343 HydrophobicContact CB-CG2 4.45Å; K339-V343 WeakPolarHBondContact O-CB 3.36Å; K339-V343 WeakPolarHBondContact O-CG2 3.33Å; K339-V343 PolarHBondContact O-N 3.37Å; V343-S345 PolarHBondContact O-N 2.87Å
344	C	39.9	Very low	48.5	Very low	122 Å²	122	109.9 Å²	109.9	82%	0.824	67%	0.671	S	S	*	*	G	3₁₀ helix	trans	-69	-8.7	172.3	-106.2	0	0	0	0	114.3
345	S	40.5	Very low	47.6	Very low	99 Å²	99	104.8 Å²	104.8	69%	0.692	66%	0.663	S	S	*	*	G	3₁₀ helix	trans	-114.5	-5.3	-176.9	47.6	0	0	0	0	115.3	S342 V343	S342-S345 PolarHBondContact O-OG 3.37Å; V343-S345 PolarHBondContact O-N 2.87Å
346	V	44.3	Very low	46.8	Very low	113 Å²	113	105.2 Å²	105.2	69%	0.685	67%	0.672	S	S	*	*			trans	-138.8	86.6	177.7	-171.6	0	0	0	0	110.1
347	A	35.2	Very low	46.3	Very low	90 Å²	90	103.2 Å²	103.2	74%	0.744	67%	0.672	S	S	*	*			trans	-130.4	56.6	-178.5	0	0	0	0	0	111.7
348	T	35.1	Very low	46.3	Very low	120 Å²	120	98.4 Å²	98.4	74%	0.736	65%	0.646	S	S	*	*			trans	-141.1	142.9	177	-7.3	0	0	0	0	111.3
349	T	36.6	Very low	46.3	Very low	131 Å²	131	96.6 Å²	96.6	80%	0.804	64%	0.644	S	S	*	*			trans	61.9	95.7	169.1	62.9	0	0	0	0	118.9
350	S	39.1	Very low	46.6	Very low	120 Å²	120	95 Å²	95	84%	0.839	64%	0.637	S	S	*	*				169.6	122	116.3	48.5	0	0	0	0	111.8	G352	S350-G352 PolarHBondContact O-N 2.74Å
351	G	32.7	Very low	47.2	Very low	94 Å²	94	92.3 Å²	92.3	97%	0.969	62%	0.622	S	S	*	*			trans	-76.9	42.5	-175.1	0	0	0	0	0	115.4
352	G	31.5	Very low	48	Very low	58 Å²	58	88.1 Å²	88.1	60%	0.598	60%	0.595	S	S	*	*			trans	-74.7	129.2	177.3	0	0	0	0	0	112	S350 A354	S350-G352 PolarHBondContact O-N 2.74Å; G352-A354 PolarHBondContact O-N 3.14Å
353	S	34	Very low	49	Very low	123 Å²	123	88.9 Å²	88.9	86%	0.86	59%	0.593	S	S	*	*			trans	-62.3	90.4	-179.2	-166.3	0	0	0	0	112.2	S355	S353-S355 PolarHBondContact O-N 3.05Å
354	A	41.6	Very low	50.2	Low	84 Å²	84	90.6 Å²	90.6	69%	0.694	59%	0.59	S	S	*	*			trans	-73.2	93.6	-174.1	0	0	0	0	0	110.7	G352 V356	G352-A354 PolarHBondContact O-N 3.14Å; A354-V356 PolarHBondContact O-N 3.26Å
355	S	49.9	Very low	52	Low	72 Å²	72	86.3 Å²	86.3	50%	0.503	56%	0.563	S	S	.	*			trans	-63	104.6	173.8	73	0	0	0	0	109.9	R248 S353 A357	R248-S355 PolarHBondContact NH1-OG 3.02Å; S353-S355 PolarHBondContact O-N 3.05Å; S355-A357 PolarHBondContact O-N 3.47Å
356	V	55.1	Low	53.8	Low	97 Å²	97	82.5 Å²	82.5	59%	0.588	54%	0.538	S	S	*	.	P	Polyproline II helix	trans	-54.3	120.7	-174.7	-177	0	0	0	0	110.4	I155 A354	I155-V356 HydrophobicContact CD1-CB 4.4Å; I155-V356 WeakPolarHBondContact CD1-O 3.49Å; A354-V356 PolarHBondContact O-N 3.26Å
357	A	57.6	Low	55.7	Low	56 Å²	56	84.2 Å²	84.2	46%	0.463	53%	0.532	S	S	.	.	P	Polyproline II helix	trans	-57.1	141.2	178	0	0	0	0	0	110.5	E245 S355 P359	E245-A357 WeakPolarHBondContact OE1-CA 3.39Å; S355-A357 PolarHBondContact O-N 3.47Å; A357-P359 WeakPolarHBondContact O-CD 3.39Å; A357-P359 VanDerWaalsContact O-N 3.15Å
358	L	62.2	Low	58.2	Low	23 Å²	23	80.3 Å²	80.3	12%	0.12	50%	0.499	C	S	.	.	P	Polyproline II helix	trans	-61.8	122	-174.9	-172.6	70	0	0	0	109.5	E245 K360 E362 I363	E245-L358 PolarHBondContact OE1-N 3.17Å; L358-K360 PolarHBondContact O-N 2.87Å; L358-E362 HydrophobicContact CD1-CB 4.39Å; L358-E362 HydrophobicContact CG-CB 4.41Å; L358-I363 HydrophobicContact CD2-CD1 4.42Å; L358-I363 HydrophobicContact CD2-CG1 3.81Å; L358-I363 HydrophobicContact CG-CG1 4.35Å
359	P	64.8	Low	60.7	Low	64 Å²	64	75.2 Å²	75.2	42%	0.416	47%	0.467	S	S	.	.	P	Polyproline II helix	trans	-57.9	133.1	-172.1	-26.7	34.4	0	0	0	111.6	A357 R361 E362	A357-P359 WeakPolarHBondContact O-CD 3.39Å; A357-P359 VanDerWaalsContact O-N 3.15Å; P359-R361 PolarHBondContact O-N 2.87Å; P359-E362 HydrophobicContact CB-CG 4.29Å; P359-E362 HydrophobicContact CG-CG 4.4Å; P359-E362 PolarHBondContact O-N 2.96Å
360	K	69.7	Low	63.3	Low	112 Å²	112	71 Å²	71	49%	0.487	45%	0.446	S	S	.	.	H	α-helix	trans	-50.9	-23.3	179.5	-64	170.3	-175.2	162.7	0	113.2	S332 E336 L358	S332-K360 PolarHBondContact OG-NZ 2.76Å; E336-K360 IonicContact OE2-NZ 3.52Å; L358-K360 PolarHBondContact O-N 2.87Å
361	R	68.9	Low	66	Low	91 Å²	91	67.7 Å²	67.7	34%	0.343	42%	0.418	S	S	.	.	H	α-helix	trans	-70.7	-43.4	174.2	-171.5	177.2	-175.4	177.8	-4.1	112.9	P359 I363 R364 A365 D439	P359-R361 PolarHBondContact O-N 2.87Å; R361-I363 VanDerWaalsContact C-N 3.34Å; R361-I363 PolarHBondContact O-N 2.9Å; R361-R364 PolarHBondContact O-N 3.19Å; R361-A365 PolarHBondContact O-N 3.43Å; R361-D439 IonicContact CZ-OD2 2.74Å; R361-D439 IonicContact NE-OD2 2.67Å; R361-D439 PolarHBondContact NE-OD2 3.18Å; R361-D439 IonicContact NH2-OD1 3.35Å; R361-D439 IonicContact NH2-OD2 3.89Å; R361-D439 PolarHBondContact NH2-OD2 3.38Å
362	E	70.4	Confident	68.9	Low	24 Å²	24	63.3 Å²	63.3	11%	0.112	37%	0.372	C	S	.	.	H	α-helix	trans	-66.3	-36.4	-178.9	-62.8	-54.2	128.2	0	0	111.6	R148 L358 P359 R364 A365 A366	R148-E362 IonicContact CZ-OE2 2.66Å; R148-E362 IonicContact NH1-OE2 2.83Å; R148-E362 PolarHBondContact NH1-OE2 2.91Å; L358-E362 HydrophobicContact CD1-CB 4.39Å; L358-E362 HydrophobicContact CG-CB 4.41Å; P359-E362 HydrophobicContact CB-CG 4.29Å; P359-E362 HydrophobicContact CG-CG 4.4Å; P359-E362 PolarHBondContact O-N 2.96Å; E362-R364 VanDerWaalsContact C-N 3.32Å; E362-R364 PolarHBondContact O-N 3.26Å; E362-A365 PolarHBondContact O-N 2.93Å; E362-A366 WeakPolarHBondContact O-CB 3.34Å; E362-A366 PolarHBondContact O-N 3.39Å
363	I	70.6	Confident	72	Confident	87 Å²	87	60.8 Å²	60.8	45%	0.446	35%	0.345	S	S	.	.	H	α-helix	trans	-62.6	-39.4	174.3	-60.5	174.9	0	0	0	111.1	L358 R361 R367	L358-I363 HydrophobicContact CD2-CD1 4.42Å; L358-I363 HydrophobicContact CD2-CG1 3.81Å; L358-I363 HydrophobicContact CG-CG1 4.35Å; R361-I363 VanDerWaalsContact C-N 3.34Å; R361-I363 PolarHBondContact O-N 2.9Å; I363-R367 PolarHBondContact O-N 2.93Å
364	R	75.5	Confident	75	Confident	123 Å²	123	56.2 Å²	56.2	46%	0.464	32%	0.317	S	S	.	.	H	α-helix	trans	-69.3	-40.9	176.2	-68.7	179.1	-171.3	151.6	9.2	112.2	R361 E362 R367 T368	R361-R364 PolarHBondContact O-N 3.19Å; E362-R364 VanDerWaalsContact C-N 3.32Å; E362-R364 PolarHBondContact O-N 3.26Å; R364-R367 PolarHBondContact O-N 3.46Å; R364-T368 PolarHBondContact O-N 2.92Å; R364-T368 PolarHBondContact O-OG1 3.42Å
365	A	75.8	Confident	77.6	Confident	31 Å²	31	52.9 Å²	52.9	26%	0.256	29%	0.289	S	S	.	.	H	α-helix	trans	-61.1	-47.6	174.4	0	0	0	0	0	110.9	R361 E362 R367 T368 L369	R361-A365 PolarHBondContact O-N 3.43Å; E362-A365 PolarHBondContact O-N 2.93Å; A365-R367 VanDerWaalsContact C-N 3.33Å; A365-R367 PolarHBondContact O-N 3.09Å; A365-T368 PolarHBondContact O-N 2.92Å; A365-T368 VanDerWaalsContact O-N 3.13Å; A365-L369 WeakPolarHBondContact O-CG 3.44Å; A365-L369 PolarHBondContact O-N 3.46Å
366	A	78.9	Confident	79.9	Confident	20 Å²	20	49.6 Å²	49.6	17%	0.165	27%	0.266	C	S	.	.	H	α-helix	trans	-58.5	-40.9	175.7	0	0	0	0	0	112.6	E362 L369 A370	E362-A366 WeakPolarHBondContact O-CB 3.34Å; E362-A366 PolarHBondContact O-N 3.39Å; A366-L369 PolarHBondContact O-N 3.44Å; A366-A370 WeakPolarHBondContact O-CB 3.49Å; A366-A370 PolarHBondContact O-N 3.01Å
367	R	84.4	Confident	81.9	Confident	148 Å²	148	46.6 Å²	46.6	56%	0.558	25%	0.246	S	C	*	.	H	α-helix	trans	-61.5	-44.1	173.7	-178.7	179.3	176.1	-174.2	-1.8	112.4	I363 R364 A365 L369 A370 I371	I363-R367 PolarHBondContact O-N 2.93Å; R364-R367 PolarHBondContact O-N 3.46Å; A365-R367 VanDerWaalsContact C-N 3.33Å; A365-R367 PolarHBondContact O-N 3.09Å; R367-L369 VanDerWaalsContact C-N 3.34Å; R367-A370 PolarHBondContact O-N 3.4Å; R367-I371 HydrophobicContact CG-CD1 4.12Å; R367-I371 WeakPolarHBondContact O-CG1 3.25Å; R367-I371 PolarHBondContact O-N 2.82Å; R367-I371 VanDerWaalsContact O-N 3.09Å
368	T	88	Confident	83.8	Confident	9 Å²	9	50.3 Å²	50.3	6%	0.055	26%	0.258	C	S	.	.	H	α-helix	trans	-62.2	-45	179.9	-54.3	0	0	0	0	110.8	R364 A365 I371 V372 I432 Y433 F436	R364-T368 PolarHBondContact O-N 2.92Å; R364-T368 PolarHBondContact O-OG1 3.42Å; A365-T368 PolarHBondContact O-N 2.92Å; A365-T368 VanDerWaalsContact O-N 3.13Å; T368-I371 WeakPolarHBondContact O-CB 3.32Å; T368-I371 PolarHBondContact O-N 3.43Å; T368-I371 VanDerWaalsContact O-N 3.15Å; T368-V372 WeakPolarHBondContact O-CG2 3.46Å; T368-V372 PolarHBondContact O-N 3.36Å; T368-I432 HydrophobicContact CG2-CG2 4.37Å; T368-Y433 HydrophobicContact CG2-CD1 4.24Å; T368-F436 HydrophobicContact CG2-CB 3.93Å; T368-F436 PolarHBondContact OG1-O 3.03Å; T368-F436 VanDerWaalsContact OG1-O 3.13Å
369	L	88.1	Confident	85.5	Confident	13 Å²	13	49.6 Å²	49.6	7%	0.068	25%	0.254	C	S	.	.	H	α-helix	trans	-67.7	-36.2	179.4	-61.3	169.5	0	0	0	112.1	I89 I144 R148 Y231 A365 A366 R367 I371 V372 T373	I89-L369 HydrophobicContact CD1-CD2 4Å; I144-L369 HydrophobicContact CG2-CB 4.28Å; I144-L369 HydrophobicContact CG2-CD1 3.76Å; I144-L369 HydrophobicContact CG2-CD2 3.87Å; I144-L369 HydrophobicContact CG2-CG 4.15Å; R148-L369 HydrophobicContact CG-CD1 3.6Å; Y231-L369 PolarHBondContact OH-O 2.88Å; Y231-L369 VanDerWaalsContact OH-O 3.14Å; A365-L369 WeakPolarHBondContact O-CG 3.44Å; A365-L369 PolarHBondContact O-N 3.46Å; A366-L369 PolarHBondContact O-N 3.44Å; R367-L369 VanDerWaalsContact C-N 3.34Å; L369-I371 VanDerWaalsContact C-N 3.28Å; L369-I371 PolarHBondContact O-N 3.31Å; L369-V372 PolarHBondContact O-N 3.47Å; L369-T373 WeakPolarHBondContact O-CB 3.25Å; L369-T373 PolarHBondContact O-N 3.38Å; L369-T373 PolarHBondContact O-OG1 3.09Å
370	A	91.4	Very high	87	Confident	43 Å²	43	46.8 Å²	46.8	36%	0.355	24%	0.235	S	C	.	.	H	α-helix	trans	-63.3	-32.9	171.8	0	0	0	0	0	112.8	Y231 A366 R367 G374	Y231-A370 HydrophobicContact CD1-CB 4.35Å; Y231-A370 HydrophobicContact CE1-CB 3.77Å; Y231-A370 PolarHBondContact OH-N 2.79Å; A366-A370 WeakPolarHBondContact O-CB 3.49Å; A366-A370 PolarHBondContact O-N 3.01Å; R367-A370 PolarHBondContact O-N 3.4Å; A370-G374 PolarHBondContact O-N 3.15Å
371	I	94.3	Very high	88.3	Confident	50 Å²	50	44.5 Å²	44.5	26%	0.256	23%	0.228	S	C	.	.	H	α-helix	trans	-70.2	-45.4	174.3	-65.7	164	0	0	0	110.6	R367 T368 L369 T373 G374 S375 I432 F436	R367-I371 HydrophobicContact CG-CD1 4.12Å; R367-I371 WeakPolarHBondContact O-CG1 3.25Å; R367-I371 PolarHBondContact O-N 2.82Å; R367-I371 VanDerWaalsContact O-N 3.09Å; T368-I371 WeakPolarHBondContact O-CB 3.32Å; T368-I371 PolarHBondContact O-N 3.43Å; T368-I371 VanDerWaalsContact O-N 3.15Å; L369-I371 VanDerWaalsContact C-N 3.28Å; L369-I371 PolarHBondContact O-N 3.31Å; I371-T373 PolarHBondContact O-N 3.28Å; I371-G374 PolarHBondContact O-N 3.25Å; I371-G374 VanDerWaalsContact O-N 3.16Å; I371-S375 PolarHBondContact O-N 3.03Å; I371-I432 HydrophobicContact CB-CG2 4.24Å; I371-I432 HydrophobicContact CG2-CD1 4.28Å; I371-I432 HydrophobicContact CG2-CG1 4.28Å; I371-I432 HydrophobicContact CG2-CG2 3.76Å; I371-F436 HydrophobicContact CD1-CD1 3.83Å; I371-F436 HydrophobicContact CD1-CD2 4.02Å; I371-F436 HydrophobicContact CD1-CE1 3.95Å; I371-F436 HydrophobicContact CD1-CE2 4.12Å; I371-F436 HydrophobicContact CD1-CG 3.87Å; I371-F436 HydrophobicContact CD1-CZ 4.08Å; I371-F436 HydrophobicContact CG2-CD2 4.41Å; I371-F436 HydrophobicContact CG2-CE2 4.29Å
372	V	95	Very high	89.7	Confident	2 Å²	2	41.8 Å²	41.8	1%	0.012	22%	0.223	C	C	.	.	H	α-helix	trans	-59.4	-44.3	174.6	172.5	0	0	0	0	111.7	L92 L141 T368 L369 G374 S375 F376 I432 Y433	L92-V372 HydrophobicContact CD2-CG1 4.44Å; L141-V372 HydrophobicContact CD2-CG1 3.85Å; T368-V372 WeakPolarHBondContact O-CG2 3.46Å; T368-V372 PolarHBondContact O-N 3.36Å; L369-V372 PolarHBondContact O-N 3.47Å; V372-G374 VanDerWaalsContact C-N 3.34Å; V372-S375 PolarHBondContact O-N 3.5Å; V372-S375 PolarHBondContact O-OG 3.38Å; V372-F376 PolarHBondContact O-N 3.08Å; V372-I432 HydrophobicContact CG2-CB 4.16Å; V372-I432 HydrophobicContact CG2-CD1 4.41Å; V372-I432 HydrophobicContact CG2-CG2 3.5Å; V372-Y433 HydrophobicContact CG2-CD1 4.43Å; V372-Y433 HydrophobicContact CG2-CE1 3.72Å
373	T	95.5	Very high	90.8	Very high	4 Å²	4	42.8 Å²	42.8	3%	0.025	23%	0.227	C	C	.	.	H	α-helix	trans	-64.7	-41	174.5	-56.8	0	0	0	0	111.2	I227 Y231 L369 I371 F376 I377	I227-T373 HydrophobicContact CD1-CG2 4.45Å; I227-T373 HydrophobicContact CG2-CG2 3.32Å; Y231-T373 HydrophobicContact CD2-CG2 4.26Å; Y231-T373 HydrophobicContact CE2-CG2 3.65Å; Y231-T373 WeakPolarHBondContact CE2-OG1 3.41Å; Y231-T373 PolarHBondContact OH-OG1 3.4Å; L369-T373 WeakPolarHBondContact O-CB 3.25Å; L369-T373 PolarHBondContact O-N 3.38Å; L369-T373 PolarHBondContact O-OG1 3.09Å; I371-T373 PolarHBondContact O-N 3.28Å; T373-F376 PolarHBondContact O-N 3.09Å; T373-I377 HydrophobicContact CG2-CD1 4Å; T373-I377 WeakPolarHBondContact O-CG1 3.42Å; T373-I377 PolarHBondContact O-N 3.07Å; T373-I377 VanDerWaalsContact O-N 3.09Å
374	G	96.3	Very high	92	Very high	27 Å²	27	39.4 Å²	39.4	28%	0.278	21%	0.209	S	C	.	.	H	α-helix	trans	-61.8	-41.6	177.5	0	0	0	0	0	113.3	A370 I371 V372 I377 L378	A370-G374 PolarHBondContact O-N 3.15Å; I371-G374 PolarHBondContact O-N 3.25Å; I371-G374 VanDerWaalsContact O-N 3.16Å; V372-G374 VanDerWaalsContact C-N 3.34Å; G374-I377 PolarHBondContact O-N 3.31Å; G374-L378 WeakPolarHBondContact O-CB 3.33Å; G374-L378 VanDerWaalsContact O-CG 3.26Å; G374-L378 WeakPolarHBondContact O-CG 3.43Å; G374-L378 PolarHBondContact O-N 3.17Å
375	S	97.3	Very high	92.9	Very high	15 Å²	15	37.3 Å²	37.3	11%	0.105	21%	0.209	C	C	.	.	H	α-helix	trans	-63.9	-43.9	175	63.5	0	0	0	0	111.3	I371 V372 I377 L378 C379 N425 I432	I371-S375 PolarHBondContact O-N 3.03Å; V372-S375 PolarHBondContact O-N 3.5Å; V372-S375 PolarHBondContact O-OG 3.38Å; S375-I377 VanDerWaalsContact C-N 3.35Å; S375-I377 PolarHBondContact O-N 2.79Å; S375-L378 PolarHBondContact O-N 2.96Å; S375-C379 VanDerWaalsContact O-CB 3.26Å; S375-C379 WeakPolarHBondContact O-CB 3.46Å; S375-C379 PolarHBondContact O-N 2.9Å; S375-C379 PolarHBondContact O-SG 2.65Å; S375-N425 WeakPolarHBondContact CB-OD1 3.47Å; S375-N425 PolarHBondContact OG-OD1 2.92Å; S375-I432 WeakPolarHBondContact OG-CD1 3.3Å
376	F	97.4	Very high	93.7	Very high	3 Å²	3	36.4 Å²	36.4	1%	0.013	20%	0.2	C	C	.	.	H	α-helix	trans	-56.6	-49.2	177.9	-172.3	-77.8	0	0	0	111.4	I138 L141 F220 V372 T373 C379 W380 N425	I138-F376 HydrophobicContact CB-CD1 4.45Å; I138-F376 HydrophobicContact CB-CE1 3.68Å; I138-F376 HydrophobicContact CB-CE2 4.45Å; I138-F376 HydrophobicContact CB-CZ 3.68Å; I138-F376 HydrophobicContact CD1-CD1 4.35Å; I138-F376 HydrophobicContact CD1-CE1 3.79Å; I138-F376 HydrophobicContact CG1-CD1 4.35Å; I138-F376 HydrophobicContact CG1-CE1 3.89Å; I138-F376 HydrophobicContact CG1-CZ 4.41Å; L141-F376 HydrophobicContact CD1-CB 3.5Å; L141-F376 VanDerWaalsContact CD1-CB 3.5Å; L141-F376 HydrophobicContact CD1-CD1 4.11Å; L141-F376 HydrophobicContact CD1-CD2 3.78Å; L141-F376 HydrophobicContact CD1-CG 3.5Å; L141-F376 VanDerWaalsContact CD1-CG 3.5Å; F220-F376 HydrophobicContact CD2-CE1 4.19Å; F220-F376 HydrophobicContact CE2-CD1 4.5Å; F220-F376 AromaticContact CE2-CE1 3.92Å; F220-F376 HydrophobicContact CE2-CE1 3.92Å; V372-F376 PolarHBondContact O-N 3.08Å; T373-F376 PolarHBondContact O-N 3.09Å; F376-C379 PolarHBondContact O-N 3.15Å; F376-W380 HydrophobicContact CD1-CB 4.46Å; F376-W380 AromaticContact CD1-CD1 3.98Å; F376-W380 HydrophobicContact CD1-CG 4.49Å; F376-W380 AromaticContact CD2-CD1 3.76Å; F376-W380 HydrophobicContact CE1-CB 4.06Å; F376-W380 AromaticContact CE1-CD1 3.71Å; F376-W380 AromaticContact CE1-CG 3.98Å; F376-W380 HydrophobicContact CE1-CG 3.98Å; F376-W380 AromaticContact CE2-CD1 3.49Å; F376-W380 VanDerWaalsContact CE2-CD1 3.49Å; F376-W380 HydrophobicContact CE2-CG 4.37Å; F376-W380 AromaticContact CE2-NE1 3.59Å; F376-W380 AromaticContact CG-CD1 3.98Å; F376-W380 HydrophobicContact CZ-CB 4.46Å; F376-W380 AromaticContact CZ-CD1 3.45Å; F376-W380 VanDerWaalsContact CZ-CD1 3.45Å; F376-W380 AromaticContact CZ-CG 3.91Å; F376-W380 HydrophobicContact CZ-CG 3.91Å; F376-W380 AromaticContact CZ-NE1 3.82Å; F376-W380 WeakPolarHBondContact O-CB 3.23Å; F376-W380 PolarHBondContact O-N 3.37Å; F376-N425 VanDerWaalsContact CA-OD1 3.26Å; F376-N425 WeakPolarHBondContact CA-OD1 3.01Å; F376-N425 WeakPolarHBondContact CD2-ND2 3.05Å; F376-N425 PolarHBondContact N-OD1 3.01Å
377	I	97.3	Very high	94.2	Very high	33 Å²	33	35.7 Å²	35.7	17%	0.169	19%	0.194	C	C	.	.	H	α-helix	trans	-63.1	-47.1	-179.8	-62.1	170.8	0	0	0	110.8	L224 I227 L228 T373 G374 S375 C379 L381	L224-I377 HydrophobicContact CD1-CD1 3.61Å; L224-I377 HydrophobicContact CD1-CG1 3.66Å; L224-I377 HydrophobicContact CD1-CG2 4.06Å; I227-I377 HydrophobicContact CG2-CD1 4.25Å; L228-I377 HydrophobicContact CD2-CD1 4.49Å; T373-I377 HydrophobicContact CG2-CD1 4Å; T373-I377 WeakPolarHBondContact O-CG1 3.42Å; T373-I377 PolarHBondContact O-N 3.07Å; T373-I377 VanDerWaalsContact O-N 3.09Å; G374-I377 PolarHBondContact O-N 3.31Å; S375-I377 VanDerWaalsContact C-N 3.35Å; S375-I377 PolarHBondContact O-N 2.79Å; I377-C379 VanDerWaalsContact C-N 3.3Å; I377-C379 PolarHBondContact O-N 3.39Å; I377-L381 WeakPolarHBondContact O-CB 3.42Å; I377-L381 PolarHBondContact O-N 3.21Å
378	L	97.4	Very high	94.4	Very high	134 Å²	134	31 Å²	31	70%	0.702	18%	0.18	S	C	*	.	H	α-helix	trans	-64.3	-34.2	-179.5	-71.7	170.5	0	0	0	112.8	G374 S375 P382	G374-L378 WeakPolarHBondContact O-CB 3.33Å; G374-L378 VanDerWaalsContact O-CG 3.26Å; G374-L378 WeakPolarHBondContact O-CG 3.43Å; G374-L378 PolarHBondContact O-N 3.17Å; S375-L378 PolarHBondContact O-N 2.96Å; L378-P382 WeakPolarHBondContact O-CD 3.13Å
379	C	97.8	Very high	94.4	Very high	8 Å²	8	36.5 Å²	36.5	5%	0.054	20%	0.201	C	C	.	.	H	α-helix	trans	-77.9	-44.2	-179.5	-81.2	0	0	0	0	113.2	S375 F376 I377 L421 N425	S375-C379 VanDerWaalsContact O-CB 3.26Å; S375-C379 WeakPolarHBondContact O-CB 3.46Å; S375-C379 PolarHBondContact O-N 2.9Å; S375-C379 PolarHBondContact O-SG 2.65Å; F376-C379 PolarHBondContact O-N 3.15Å; I377-C379 VanDerWaalsContact C-N 3.3Å; I377-C379 PolarHBondContact O-N 3.39Å; C379-L421 HydrophobicContact CB-CG 4.35Å; C379-L421 VanDerWaalsContact CB-O 3.22Å; C379-L421 WeakPolarHBondContact CB-O 3.2Å; C379-L421 PolarHBondContact SG-O 2.84Å; C379-N425 HydrophobicContact CB-CB 3.78Å
380	W	97.9	Very high	94.2	Very high	5 Å²	5	36.7 Å²	36.7	2%	0.019	20%	0.201	C	C	.	.	H	α-helix	trans	-90.9	-27.2	-172.8	-79	100.5	0	0	0	114.5	C134 F220 F376 P382 F383 F384 G422 Y423	C134-W380 HydrophobicContact CB-CH2 3.96Å; C134-W380 HydrophobicContact CB-CZ2 4.09Å; C134-W380 HydrophobicContact CB-CZ3 4.37Å; F220-W380 HydrophobicContact CD2-CB 4.49Å; F220-W380 HydrophobicContact CE2-CB 3.75Å; F220-W380 HydrophobicContact CZ-CB 4.38Å; F376-W380 HydrophobicContact CD1-CB 4.46Å; F376-W380 AromaticContact CD1-CD1 3.98Å; F376-W380 HydrophobicContact CD1-CG 4.49Å; F376-W380 AromaticContact CD2-CD1 3.76Å; F376-W380 HydrophobicContact CE1-CB 4.06Å; F376-W380 AromaticContact CE1-CD1 3.71Å; F376-W380 AromaticContact CE1-CG 3.98Å; F376-W380 HydrophobicContact CE1-CG 3.98Å; F376-W380 AromaticContact CE2-CD1 3.49Å; F376-W380 VanDerWaalsContact CE2-CD1 3.49Å; F376-W380 HydrophobicContact CE2-CG 4.37Å; F376-W380 AromaticContact CE2-NE1 3.59Å; F376-W380 AromaticContact CG-CD1 3.98Å; F376-W380 HydrophobicContact CZ-CB 4.46Å; F376-W380 AromaticContact CZ-CD1 3.45Å; F376-W380 VanDerWaalsContact CZ-CD1 3.45Å; F376-W380 AromaticContact CZ-CG 3.91Å; F376-W380 HydrophobicContact CZ-CG 3.91Å; F376-W380 AromaticContact CZ-NE1 3.82Å; F376-W380 WeakPolarHBondContact O-CB 3.23Å; F376-W380 PolarHBondContact O-N 3.37Å; W380-P382 VanDerWaalsContact C-CD 3.48Å; W380-F383 HydrophobicContact CE3-CD1 4.06Å; W380-F383 AromaticContact CZ3-CD1 3.99Å; W380-F383 HydrophobicContact CZ3-CD1 3.99Å; W380-F383 HydrophobicContact CZ3-CE1 4.37Å; W380-F383 PolarHBondContact O-N 3.23Å; W380-F384 HydrophobicContact CB-CD2 4.02Å; W380-F384 HydrophobicContact CB-CE2 4.09Å; W380-F384 HydrophobicContact CD2-CE2 4.13Å; W380-F384 HydrophobicContact CE3-CD2 4.17Å; W380-F384 AromaticContact CE3-CE2 3.55Å; W380-F384 HydrophobicContact CE3-CE2 3.55Å; W380-F384 HydrophobicContact CE3-CZ 4.34Å; W380-F384 HydrophobicContact CG-CE2 4.39Å; W380-F384 HydrophobicContact CZ3-CE2 4.3Å; W380-F384 WeakPolarHBondContact O-CD2 3.19Å; W380-F384 PolarHBondContact O-N 3.02Å; W380-G422 PolarHBondContact NE1-O 2.87Å; W380-Y423 HydrophobicContact CH2-CD1 4.24Å; W380-Y423 HydrophobicContact CH2-CE1 4.18Å; W380-Y423 HydrophobicContact CZ2-CD1 4.4Å
381	L	97.2	Very high	93.7	Very high	65 Å²	65	35 Å²	35	34%	0.34	19%	0.186	S	C	.	.	H	α-helix	trans	-55.8	-41.4	-177.9	-179.9	64.9	0	0	0	113.8	F220 I377 F383 F384 V385	F220-L381 HydrophobicContact CE1-CD1 3.85Å; F220-L381 HydrophobicContact CZ-CB 4.15Å; F220-L381 HydrophobicContact CZ-CD1 4.24Å; I377-L381 WeakPolarHBondContact O-CB 3.42Å; I377-L381 PolarHBondContact O-N 3.21Å; L381-F383 PolarHBondContact O-N 3.49Å; L381-F384 PolarHBondContact O-N 2.93Å; L381-V385 HydrophobicContact CD1-CG2 3.92Å; L381-V385 HydrophobicContact CG-CG2 4.26Å; L381-V385 WeakPolarHBondContact O-CB 3.13Å; L381-V385 VanDerWaalsContact O-CG2 3.29Å; L381-V385 WeakPolarHBondContact O-CG2 3.3Å; L381-V385 PolarHBondContact O-N 3.45Å
382	P	96.9	Very high	93	Very high	34 Å²	34	37.9 Å²	37.9	22%	0.221	20%	0.201	C	C	.	.	H	α-helix	trans	-59.4	-43.7	177.2	-25.3	36.7	0	0	0	112.9	L378 W380 V385 L386 F418 L421	L378-P382 WeakPolarHBondContact O-CD 3.13Å; W380-P382 VanDerWaalsContact C-CD 3.48Å; P382-V385 PolarHBondContact O-N 2.98Å; P382-L386 PolarHBondContact O-N 3.48Å; P382-F418 VanDerWaalsContact C-CD2 3.47Å; P382-F418 HydrophobicContact CB-CB 4.4Å; P382-F418 HydrophobicContact CB-CD1 3.81Å; P382-F418 HydrophobicContact CB-CD2 3.67Å; P382-F418 HydrophobicContact CB-CE1 3.88Å; P382-F418 HydrophobicContact CB-CE2 3.75Å; P382-F418 HydrophobicContact CB-CG 3.7Å; P382-F418 HydrophobicContact CB-CZ 3.85Å; P382-F418 VanDerWaalsContact O-CD2 3.26Å; P382-F418 WeakPolarHBondContact O-CD2 3.34Å; P382-L421 HydrophobicContact CG-CD2 4.08Å
383	F	94.8	Very high	92.2	Very high	45 Å²	45	38.8 Å²	38.8	20%	0.197	21%	0.209	C	C	.	.	H	α-helix	trans	-64	-47.4	176.5	179.2	-99.3	0	0	0	111.9	W380 L381 V385 L386 A387 F418 L419	W380-F383 HydrophobicContact CE3-CD1 4.06Å; W380-F383 AromaticContact CZ3-CD1 3.99Å; W380-F383 HydrophobicContact CZ3-CD1 3.99Å; W380-F383 HydrophobicContact CZ3-CE1 4.37Å; W380-F383 PolarHBondContact O-N 3.23Å; L381-F383 PolarHBondContact O-N 3.49Å; F383-V385 VanDerWaalsContact C-N 3.33Å; F383-V385 PolarHBondContact O-N 2.86Å; F383-L386 CarbonylContact O-C 3.44Å; F383-L386 WeakPolarHBondContact O-CB 3.38Å; F383-L386 PolarHBondContact O-N 2.97Å; F383-L386 VanDerWaalsContact O-N 3.14Å; F383-A387 WeakPolarHBondContact O-CB 3.3Å; F383-A387 PolarHBondContact O-N 3.18Å; F383-F418 HydrophobicContact CB-CB 4.29Å; F383-L419 HydrophobicContact CD2-CB 4.24Å; F383-L419 HydrophobicContact CD2-CD1 4.1Å; F383-L419 HydrophobicContact CE2-CB 4.34Å; F383-L419 HydrophobicContact CE2-CD1 3.67Å; F383-L419 HydrophobicContact CZ-CD1 4.02Å
384	F	95	Very high	91.3	Very high	16 Å²	16	39.7 Å²	39.7	7%	0.07	22%	0.215	C	C	.	.	H	α-helix	trans	-67.6	-30.8	-179.9	-78.9	-74	0	0	0	113.7	T216 F220 Y221 W380 L381 A387 L388	T216-F384 HydrophobicContact CG2-CD1 4.24Å; F220-F384 HydrophobicContact CB-CB 4.5Å; F220-F384 HydrophobicContact CB-CD1 3.56Å; F220-F384 HydrophobicContact CB-CD2 3.81Å; F220-F384 HydrophobicContact CB-CE1 3.59Å; F220-F384 HydrophobicContact CB-CE2 3.83Å; F220-F384 HydrophobicContact CB-CG 3.68Å; F220-F384 HydrophobicContact CB-CZ 3.73Å; F220-F384 HydrophobicContact CD1-CB 3.53Å; F220-F384 HydrophobicContact CD1-CD1 4.21Å; F220-F384 AromaticContact CD1-CD2 3.73Å; F220-F384 HydrophobicContact CD1-CD2 3.73Å; F220-F384 AromaticContact CD1-CG 3.55Å; F220-F384 HydrophobicContact CD1-CG 3.55Å; F220-F384 AromaticContact CD2-CD2 3.24Å; F220-F384 HydrophobicContact CD2-CD2 3.24Å; F220-F384 AromaticContact CD2-CE2 3.36Å; F220-F384 HydrophobicContact CD2-CE2 3.36Å; F220-F384 AromaticContact CD2-CG 3.91Å; F220-F384 HydrophobicContact CD2-CG 3.91Å; F220-F384 HydrophobicContact CD2-CZ 4.11Å; F220-F384 HydrophobicContact CE1-CB 3.77Å; F220-F384 HydrophobicContact CE1-CD2 4.03Å; F220-F384 HydrophobicContact CE1-CG 4.08Å; F220-F384 AromaticContact CE2-CD2 3.59Å; F220-F384 HydrophobicContact CE2-CD2 3.59Å; F220-F384 AromaticContact CE2-CE2 3.98Å; F220-F384 HydrophobicContact CE2-CE2 3.98Å; F220-F384 HydrophobicContact CE2-CG 4.4Å; F220-F384 HydrophobicContact CG-CB 4Å; F220-F384 AromaticContact CG-CD1 3.9Å; F220-F384 HydrophobicContact CG-CD1 3.9Å; F220-F384 AromaticContact CG-CD2 3.31Å; F220-F384 HydrophobicContact CG-CD2 3.31Å; F220-F384 HydrophobicContact CG-CE1 4.22Å; F220-F384 AromaticContact CG-CE2 3.67Å; F220-F384 HydrophobicContact CG-CE2 3.67Å; F220-F384 AromaticContact CG-CG 3.44Å; F220-F384 HydrophobicContact CG-CG 3.44Å; F220-F384 VanDerWaalsContact CG-CG 3.44Å; F220-F384 HydrophobicContact CG-CZ 4.12Å; F220-F384 HydrophobicContact CZ-CB 4.41Å; F220-F384 AromaticContact CZ-CD2 3.97Å; F220-F384 HydrophobicContact CZ-CD2 3.97Å; F220-F384 HydrophobicContact CZ-CG 4.48Å; Y221-F384 HydrophobicContact CE2-CB 4.1Å; Y221-F384 PolarHBondContact OH-O 3.3Å; Y221-F384 VanDerWaalsContact OH-O 3.08Å; W380-F384 HydrophobicContact CB-CD2 4.02Å; W380-F384 HydrophobicContact CB-CE2 4.09Å; W380-F384 HydrophobicContact CD2-CE2 4.13Å; W380-F384 HydrophobicContact CE3-CD2 4.17Å; W380-F384 AromaticContact CE3-CE2 3.55Å; W380-F384 HydrophobicContact CE3-CE2 3.55Å; W380-F384 HydrophobicContact CE3-CZ 4.34Å; W380-F384 HydrophobicContact CG-CE2 4.39Å; W380-F384 HydrophobicContact CZ3-CE2 4.3Å; W380-F384 WeakPolarHBondContact O-CD2 3.19Å; W380-F384 PolarHBondContact O-N 3.02Å; L381-F384 PolarHBondContact O-N 2.93Å; F384-A387 PolarHBondContact O-N 3.01Å; F384-L388 PolarHBondContact O-N 2.98Å; F384-L388 VanDerWaalsContact O-N 3.12Å
385	V	94.5	Very high	89.7	Confident	78 Å²	78	42.4 Å²	42.4	47%	0.473	23%	0.23	S	C	.	.	H	α-helix	trans	-64.8	-45	170	168.8	0	0	0	0	110.7	Y221 L381 P382 F383 A387 L388 Y389	Y221-V385 PolarHBondContact OH-N 3.19Å; L381-V385 HydrophobicContact CD1-CG2 3.92Å; L381-V385 HydrophobicContact CG-CG2 4.26Å; L381-V385 WeakPolarHBondContact O-CB 3.13Å; L381-V385 VanDerWaalsContact O-CG2 3.29Å; L381-V385 WeakPolarHBondContact O-CG2 3.3Å; L381-V385 PolarHBondContact O-N 3.45Å; P382-V385 PolarHBondContact O-N 2.98Å; F383-V385 VanDerWaalsContact C-N 3.33Å; F383-V385 PolarHBondContact O-N 2.86Å; V385-A387 VanDerWaalsContact C-N 3.28Å; V385-A387 PolarHBondContact O-N 3.43Å; V385-L388 PolarHBondContact O-N 3.05Å; V385-Y389 PolarHBondContact O-N 3.42Å
386	L	91.5	Very high	87.7	Confident	12 Å²	12	45.8 Å²	45.8	6%	0.063	25%	0.253	C	S	.	.	H	α-helix	trans	-63.9	-35.2	175.3	-170.2	63	0	0	0	111.9	P382 F383 L388 Y389 R390 I410 D415 F418	P382-L386 PolarHBondContact O-N 3.48Å; F383-L386 CarbonylContact O-C 3.44Å; F383-L386 WeakPolarHBondContact O-CB 3.38Å; F383-L386 PolarHBondContact O-N 2.97Å; F383-L386 VanDerWaalsContact O-N 3.14Å; L386-L388 PolarHBondContact O-N 2.94Å; L386-Y389 HydrophobicContact CD1-CD1 4.26Å; L386-Y389 PolarHBondContact O-N 3.35Å; L386-R390 VanDerWaalsContact O-CB 3.31Å; L386-R390 WeakPolarHBondContact O-CB 3.21Å; L386-R390 PolarHBondContact O-N 3Å; L386-I410 HydrophobicContact CD1-CD1 3.82Å; L386-I410 HydrophobicContact CD1-CG1 4.11Å; L386-I410 HydrophobicContact CD1-CG2 3.93Å; L386-I410 HydrophobicContact CD2-CG2 4.12Å; L386-I410 HydrophobicContact CG-CD1 4.48Å; L386-I410 HydrophobicContact CG-CG2 4.47Å; L386-D415 HydrophobicContact CD2-CB 4.23Å; L386-D415 WeakPolarHBondContact CD2-OD1 3.41Å; L386-F418 HydrophobicContact CB-CD2 4.09Å; L386-F418 HydrophobicContact CD2-CD2 3.96Å
387	A	89.8	Confident	85.5	Confident	6 Å²	6	48.2 Å²	48.2	5%	0.05	27%	0.271	C	S	.	.	H	α-helix	trans	-67.9	-30.4	178.5	0	0	0	0	0	113.6	Q212 T216 F383 F384 V385 P391	Q212-A387 WeakPolarHBondContact CG-O 3Å; Q212-A387 PolarHBondContact NE2-O 2.8Å; T216-A387 HydrophobicContact CG2-CB 3.89Å; F383-A387 WeakPolarHBondContact O-CB 3.3Å; F383-A387 PolarHBondContact O-N 3.18Å; F384-A387 PolarHBondContact O-N 3.01Å; V385-A387 VanDerWaalsContact C-N 3.28Å; V385-A387 PolarHBondContact O-N 3.43Å; A387-P391 WeakPolarHBondContact O-CD 3.35Å
388	L	89.1	Confident	83.2	Confident	48 Å²	48	53.1 Å²	53.1	25%	0.251	30%	0.296	S	S	.	.	H	α-helix	trans	-77	-37.7	168.6	-73.8	-178.9	0	0	0	112.5	L213 T216 Y221 F384 V385 L386	L213-L388 HydrophobicContact CD2-CD2 3.68Å; T216-L388 VanDerWaalsContact OG1-CD2 3.23Å; T216-L388 WeakPolarHBondContact OG1-CD2 3.15Å; Y221-L388 HydrophobicContact CD2-CD1 4.3Å; Y221-L388 HydrophobicContact CE1-CD1 4.36Å; Y221-L388 HydrophobicContact CE2-CD1 3.47Å; Y221-L388 VanDerWaalsContact CE2-CD1 3.47Å; Y221-L388 HydrophobicContact CE2-CD2 4.39Å; Y221-L388 HydrophobicContact CE2-CG 3.82Å; Y221-L388 WeakPolarHBondContact OH-CD1 3.22Å; F384-L388 PolarHBondContact O-N 2.98Å; F384-L388 VanDerWaalsContact O-N 3.12Å; V385-L388 PolarHBondContact O-N 3.05Å; L386-L388 PolarHBondContact O-N 2.94Å
389	Y	87.4	Confident	81	Confident	125 Å²	125	55.6 Å²	55.6	49%	0.49	30%	0.304	S	S	.	.	H	α-helix	trans	-70.6	-38.7	-179.1	178.6	-115.3	0	0	0	112.6	V385 L386 I392 A393 I410	V385-Y389 PolarHBondContact O-N 3.42Å; L386-Y389 HydrophobicContact CD1-CD1 4.26Å; L386-Y389 PolarHBondContact O-N 3.35Å; Y389-I392 PolarHBondContact O-N 3.35Å; Y389-I392 VanDerWaalsContact O-N 3.08Å; Y389-A393 HydrophobicContact CD1-CB 3.8Å; Y389-A393 HydrophobicContact CD2-CB 4.31Å; Y389-A393 HydrophobicContact CE1-CB 3.41Å; Y389-A393 VanDerWaalsContact CE1-CB 3.41Å; Y389-A393 HydrophobicContact CE2-CB 3.96Å; Y389-A393 HydrophobicContact CG-CB 4.24Å; Y389-A393 VanDerWaalsContact CZ-CB 3.5Å; Y389-A393 WeakPolarHBondContact O-CB 3.39Å; Y389-A393 PolarHBondContact O-N 2.9Å; Y389-I410 HydrophobicContact CD1-CD1 4.22Å; Y389-I410 HydrophobicContact CD1-CG1 4.4Å; Y389-I410 HydrophobicContact CE1-CG1 4.29Å
390	R	85.4	Confident	78.4	Confident	18 Å²	18	59.9 Å²	59.9	7%	0.068	33%	0.327	C	S	.	.	H	α-helix	trans	-53	-51.5	-172.6	177.3	-171	-66	-105	6.1	114	L386 I392 A393 C394 I410 D415	L386-R390 VanDerWaalsContact O-CB 3.31Å; L386-R390 WeakPolarHBondContact O-CB 3.21Å; L386-R390 PolarHBondContact O-N 3Å; R390-I392 VanDerWaalsContact C-N 3.28Å; R390-I392 PolarHBondContact O-N 2.97Å; R390-A393 PolarHBondContact O-N 3Å; R390-C394 VanDerWaalsContact CG-SG 3.59Å; R390-C394 WeakPolarHBondContact O-CB 3.44Å; R390-C394 PolarHBondContact O-N 3.08Å; R390-C394 PolarHBondContact O-SG 2.74Å; R390-I410 HydrophobicContact CB-CD1 3.88Å; R390-I410 HydrophobicContact CG-CD1 4.08Å; R390-D415 IonicContact CZ-OD1 3.25Å; R390-D415 IonicContact CZ-OD2 2.8Å; R390-D415 IonicContact NH2-OD1 3.53Å; R390-D415 PolarHBondContact NH2-OD1 3.5Å; R390-D415 IonicContact NH2-OD2 2.66Å; R390-D415 PolarHBondContact NH2-OD2 2.84Å
391	P	79.3	Confident	76.1	Confident	8 Å²	8	67.7 Å²	67.7	5%	0.052	37%	0.369	C	S	.	.	H	α-helix	trans	-55.4	-43	177	-28.2	36.6	0	0	0	112.9	L209 Q212 A387 S395	L209-P391 HydrophobicContact CD1-CB 3.5Å; L209-P391 VanDerWaalsContact CD1-CB 3.5Å; L209-P391 HydrophobicContact CD1-CG 4.4Å; Q212-P391 HydrophobicContact CB-CG 3.92Å; Q212-P391 HydrophobicContact CG-CG 3.54Å; A387-P391 WeakPolarHBondContact O-CD 3.35Å; P391-S395 WeakPolarHBondContact O-CB 3.39Å; P391-S395 PolarHBondContact O-N 3.3Å
392	I	79.7	Confident	73.8	Confident	109 Å²	109	71.2 Å²	71.2	56%	0.559	39%	0.387	S	S	*	.	H	α-helix	trans	-68.4	-45.5	-179.4	-55	171.4	0	0	0	110.4	Y389 R390	Y389-I392 PolarHBondContact O-N 3.35Å; Y389-I392 VanDerWaalsContact O-N 3.08Å; R390-I392 VanDerWaalsContact C-N 3.28Å; R390-I392 PolarHBondContact O-N 2.97Å
393	A	79.8	Confident	71.2	Confident	22 Å²	22	74 Å²	74	18%	0.182	41%	0.406	C	S	.	.	H	α-helix	trans	-68.6	-33.9	-177.1	0	0	0	0	0	113.6	Y389 R390	Y389-A393 HydrophobicContact CD1-CB 3.8Å; Y389-A393 HydrophobicContact CD2-CB 4.31Å; Y389-A393 HydrophobicContact CE1-CB 3.41Å; Y389-A393 VanDerWaalsContact CE1-CB 3.41Å; Y389-A393 HydrophobicContact CE2-CB 3.96Å; Y389-A393 HydrophobicContact CG-CB 4.24Å; Y389-A393 VanDerWaalsContact CZ-CB 3.5Å; Y389-A393 WeakPolarHBondContact O-CB 3.39Å; Y389-A393 PolarHBondContact O-N 2.9Å; R390-A393 PolarHBondContact O-N 3Å
394	C	74.5	Confident	68.9	Low	23 Å²	23	78.6 Å²	78.6	16%	0.155	44%	0.439	C	S	.	.	H	α-helix	trans	-99.5	-15.3	-177.3	-37.9	0	0	0	0	113.4	R390 S396 S397 C408	R390-C394 VanDerWaalsContact CG-SG 3.59Å; R390-C394 WeakPolarHBondContact O-CB 3.44Å; R390-C394 PolarHBondContact O-N 3.08Å; R390-C394 PolarHBondContact O-SG 2.74Å; C394-S396 VanDerWaalsContact C-N 3.27Å; C394-S396 PolarHBondContact O-N 3.48Å; C394-S397 WeakPolarHBondContact O-CB 3.4Å; C394-S397 PolarHBondContact O-N 3.34Å; C394-S397 PolarHBondContact O-OG 2.84Å; C394-S397 VanDerWaalsContact O-OG 3.08Å; C394-C408 VanDerWaalsContact CA-SG 3.56Å; C394-C408 HydrophobicContact CB-CB 3.76Å; C394-C408 WeakPolarHBondContact CB-SG 3.47Å; C394-C408 WeakPolarHBondContact SG-CB 3.48Å; C394-C408 CovalentContact SG-SG 2.03Å; C394-C408 PolarHBondContact SG-SG 3.33Å
395	S	64.7	Low	66.7	Low	84 Å²	84	82.4 Å²	82.4	59%	0.587	47%	0.467	S	S	*	.	H	α-helix	trans	-66.8	-27.1	178.5	-178.7	0	0	0	0	113.1	P391 S397 L398	P391-S395 WeakPolarHBondContact O-CB 3.39Å; P391-S395 PolarHBondContact O-N 3.3Å; S395-S397 PolarHBondContact O-N 2.73Å; S395-S397 VanDerWaalsContact O-N 3.09Å; S395-L398 PolarHBondContact O-N 2.03Å
396	S	53.5	Low	64.5	Low	86 Å²	86	84.6 Å²	84.6	60%	0.601	48%	0.476	S	S	*	.	T	Hydrogen-bonded Turn	trans	-65.7	-9.3	179.2	-49.9	0	0	0	0	113.9	C394	C394-S396 VanDerWaalsContact C-N 3.27Å; C394-S396 PolarHBondContact O-N 3.48Å
397	S	51.5	Low	62.7	Low	54 Å²	54	90.6 Å²	90.6	38%	0.378	50%	0.499	S	S	.	.	T	Hydrogen-bonded Turn	trans	-85.9	-9.1	-176.4	-44.3	0	0	0	0	114.2	C394 S395 Y407	C394-S397 WeakPolarHBondContact O-CB 3.4Å; C394-S397 PolarHBondContact O-N 3.34Å; C394-S397 PolarHBondContact O-OG 2.84Å; C394-S397 VanDerWaalsContact O-OG 3.08Å; S395-S397 PolarHBondContact O-N 2.73Å; S395-S397 VanDerWaalsContact O-N 3.09Å; S397-Y407 PolarHBondContact OG-O 3.05Å
398	L	49.5	Very low	61.7	Low	136 Å²	136	91.1 Å²	91.1	71%	0.712	50%	0.503	S	S	*	.	S	Bend	trans	-98.4	-19.5	-170.7	-161	67.1	0	0	0	114.6	S395	S395-L398 PolarHBondContact O-N 2.03Å
399	E	50.4	Low	60.9	Low	186 Å²	186	95.5 Å²	95.5	87%	0.869	53%	0.526	S	S	*	.	S	Bend	trans	-88.8	-15	177.3	-74.7	-171.7	136.2	0	0	113.8
400	N	44.7	Very low	60.6	Low	98 Å²	98	90.4 Å²	90.4	52%	0.524	51%	0.507	S	S	.	.	S	Bend	trans	-109.2	120	177.4	-63	-66.8	0	0	0	109.2	I402	N400-I402 HydrophobicContact CB-CD1 3.87Å; N400-I402 HydrophobicContact CB-CG1 4.01Å; N400-I402 PolarHBondContact O-N 3.49Å
401	N	49.8	Very low	60.7	Low	168 Å²	168	93 Å²	93	90%	0.898	53%	0.526	S	S	*	.			trans	-69.7	57.7	176.3	-73.8	-40.2	0	0	0	112.2
402	I	47.6	Very low	60.9	Low	140 Å²	140	97.4 Å²	97.4	72%	0.718	56%	0.555	S	S	*	*			trans	-103.9	120.2	-177.5	-63.5	175.2	0	0	0	109	N400 T404	N400-I402 HydrophobicContact CB-CD1 3.87Å; N400-I402 HydrophobicContact CB-CG1 4.01Å; N400-I402 PolarHBondContact O-N 3.49Å; I402-T404 PolarHBondContact O-N 2.91Å; I402-T404 VanDerWaalsContact O-N 3.08Å
403	S	43.3	Very low	61.2	Low	91 Å²	91	98.4 Å²	98.4	64%	0.636	56%	0.561	S	S	*	*			trans	-47.2	105.5	-176.2	-47.9	0	0	0	0	114.8	S405	S403-S405 VanDerWaalsContact C-N 3.25Å; S403-S405 PolarHBondContact O-N 3.44Å; S403-S405 PolarHBondContact O-OG 2.99Å
404	T	46.2	Very low	61.8	Low	143 Å²	143	100.7 Å²	100.7	88%	0.877	57%	0.57	S	S	*	*	S	Bend		47.4	6.6	127.1	43.5	0	0	0	0	122.4	I402	I402-T404 PolarHBondContact O-N 2.91Å; I402-T404 VanDerWaalsContact O-N 3.08Å
405	S	47.6	Very low	62.4	Low	96 Å²	96	101.1 Å²	101.1	67%	0.671	57%	0.57	S	S	*	*	S	Bend	trans	-114.6	-28.4	177	64.7	0	0	0	0	115.1	S403	S403-S405 VanDerWaalsContact C-N 3.25Å; S403-S405 PolarHBondContact O-N 3.44Å; S403-S405 PolarHBondContact O-OG 2.99Å
406	N	48.4	Very low	63.6	Low	124 Å²	124	98.5 Å²	98.5	66%	0.663	55%	0.552	S	S	*	*			trans	-115.2	56	-176.3	-71	-33.7	0	0	0	112.4	C408	N406-C408 PolarHBondContact O-N 3.01Å; N406-C408 VanDerWaalsContact O-N 3.15Å
407	Y	55.2	Low	65.5	Low	137 Å²	137	98.1 Å²	98.1	54%	0.537	55%	0.546	S	S	.	.	S	Bend	trans	-64	-21.8	-172.3	88.3	-88.5	0	0	0	114.5	S397	S397-Y407 PolarHBondContact OG-O 3.05Å
408	C	67.4	Low	67.6	Low	18 Å²	18	98.1 Å²	98.1	12%	0.122	54%	0.539	C	S	.	.			trans	-162.1	143.1	166.3	-158.3	0	0	0	0	111.7	C394 N406 I410	C394-C408 VanDerWaalsContact CA-SG 3.56Å; C394-C408 HydrophobicContact CB-CB 3.76Å; C394-C408 WeakPolarHBondContact CB-SG 3.47Å; C394-C408 WeakPolarHBondContact SG-CB 3.48Å; C394-C408 CovalentContact SG-SG 2.03Å; C394-C408 PolarHBondContact SG-SG 3.33Å; N406-C408 PolarHBondContact O-N 3.01Å; N406-C408 VanDerWaalsContact O-N 3.15Å; C408-I410 PolarHBondContact O-N 3.47Å
409	N	72.3	Confident	69.7	Low	140 Å²	140	92.5 Å²	92.5	75%	0.749	51%	0.51	S	S	*	.	S	Bend	trans	-78.4	31.6	178.1	-73.7	-21.8	0	0	0	113.9
410	I	82.8	Confident	71.9	Confident	18 Å²	18	84.2 Å²	84.2	9%	0.092	47%	0.471	C	S	.	.	S	Bend	trans	-102.3	114.7	174.8	-65.3	169.9	0	0	0	107.6	L386 Y389 R390 C408 D415	L386-I410 HydrophobicContact CD1-CD1 3.82Å; L386-I410 HydrophobicContact CD1-CG1 4.11Å; L386-I410 HydrophobicContact CD1-CG2 3.93Å; L386-I410 HydrophobicContact CD2-CG2 4.12Å; L386-I410 HydrophobicContact CG-CD1 4.48Å; L386-I410 HydrophobicContact CG-CG2 4.47Å; Y389-I410 HydrophobicContact CD1-CD1 4.22Å; Y389-I410 HydrophobicContact CD1-CG1 4.4Å; Y389-I410 HydrophobicContact CE1-CG1 4.29Å; R390-I410 HydrophobicContact CB-CD1 3.88Å; R390-I410 HydrophobicContact CG-CD1 4.08Å; C408-I410 PolarHBondContact O-N 3.47Å; I410-D415 HydrophobicContact CG2-CB 4.4Å
411	P	86.5	Confident	74.4	Confident	72 Å²	72	82.6 Å²	82.6	47%	0.468	46%	0.462	S	S	.	.			trans	-60.1	129.1	178.4	-24	34.1	0	0	0	111.1	L413 L414 D415	P411-L413 PolarHBondContact O-N 2.76Å; P411-L413 VanDerWaalsContact O-N 3.14Å; P411-L414 HydrophobicContact CB-CB 4.19Å; P411-L414 WeakPolarHBondContact O-CB 3.5Å; P411-L414 PolarHBondContact O-N 2.96Å; P411-D415 PolarHBondContact O-N 3.41Å
412	P	83	Confident	76.6	Confident	101 Å²	101	74.6 Å²	74.6	66%	0.656	42%	0.419	S	S	*	.	H	α-helix	trans	-56.3	-34.2	-178.7	-28.8	35.7	0	0	0	113.8	L414 D415 S416	P412-L414 VanDerWaalsContact C-N 3.34Å; P412-L414 PolarHBondContact O-N 3.2Å; P412-D415 PolarHBondContact O-N 3.09Å; P412-S416 PolarHBondContact O-N 3.27Å
413	L	87.3	Confident	79	Confident	130 Å²	130	68 Å²	68	68%	0.681	39%	0.385	S	S	*	.	H	α-helix	trans	-63.8	-36	174.8	-178.2	63.2	0	0	0	112.7	P411 V417	P411-L413 PolarHBondContact O-N 2.76Å; P411-L413 VanDerWaalsContact O-N 3.14Å; L413-V417 HydrophobicContact CD1-CG2 4.02Å; L413-V417 HydrophobicContact CG-CG2 4.32Å; L413-V417 VanDerWaalsContact O-CB 3.27Å; L413-V417 WeakPolarHBondContact O-CB 3.5Å; L413-V417 WeakPolarHBondContact O-CG2 3.38Å; L413-V417 PolarHBondContact O-N 3.36Å
414	L	90.7	Very high	81.6	Confident	70 Å²	70	65.3 Å²	65.3	37%	0.366	37%	0.365	S	S	.	.	H	α-helix	trans	-66.7	-41.8	178.4	-176.1	67.2	0	0	0	110.8	P411 P412 F418	P411-L414 HydrophobicContact CB-CB 4.19Å; P411-L414 WeakPolarHBondContact O-CB 3.5Å; P411-L414 PolarHBondContact O-N 2.96Å; P412-L414 VanDerWaalsContact C-N 3.34Å; P412-L414 PolarHBondContact O-N 3.2Å; L414-F418 HydrophobicContact CD1-CD1 4.21Å; L414-F418 HydrophobicContact CD1-CE1 3.62Å; L414-F418 HydrophobicContact CD1-CE2 4.07Å; L414-F418 HydrophobicContact CD1-CZ 3.55Å; L414-F418 HydrophobicContact CG-CD2 4.49Å; L414-F418 HydrophobicContact CG-CE1 4.45Å; L414-F418 HydrophobicContact CG-CE2 4.2Å; L414-F418 HydrophobicContact CG-CZ 4.18Å; L414-F418 WeakPolarHBondContact O-CB 3.29Å; L414-F418 WeakPolarHBondContact O-CG 3.43Å; L414-F418 PolarHBondContact O-N 3.03Å
415	D	87	Confident	84	Confident	32 Å²	32	58.5 Å²	58.5	17%	0.171	32%	0.323	C	S	.	.	H	α-helix	trans	-64.8	-51.7	178.8	-166.5	41	0	0	0	111.8	L386 R390 I410 P411 P412 V417 F418 L419	L386-D415 HydrophobicContact CD2-CB 4.23Å; L386-D415 WeakPolarHBondContact CD2-OD1 3.41Å; R390-D415 IonicContact CZ-OD1 3.25Å; R390-D415 IonicContact CZ-OD2 2.8Å; R390-D415 IonicContact NH2-OD1 3.53Å; R390-D415 PolarHBondContact NH2-OD1 3.5Å; R390-D415 IonicContact NH2-OD2 2.66Å; R390-D415 PolarHBondContact NH2-OD2 2.84Å; I410-D415 HydrophobicContact CG2-CB 4.4Å; P411-D415 PolarHBondContact O-N 3.41Å; P412-D415 PolarHBondContact O-N 3.09Å; D415-V417 PolarHBondContact O-N 2.74Å; D415-F418 PolarHBondContact O-N 3Å; D415-L419 WeakPolarHBondContact O-CB 3.18Å; D415-L419 PolarHBondContact O-N 2.87Å
416	S	90.5	Very high	86.4	Confident	29 Å²	29	54 Å²	54	20%	0.203	29%	0.292	C	S	.	.	H	α-helix	trans	-57.5	-47.7	174.5	173.6	0	0	0	0	111.3	D111 P412 F418 L419 W420	D111-S416 PolarHBondContact OD2-OG 3.22Å; P412-S416 PolarHBondContact O-N 3.27Å; S416-F418 VanDerWaalsContact C-N 3.35Å; S416-F418 PolarHBondContact O-N 2.74Å; S416-L419 PolarHBondContact O-N 3.1Å; S416-W420 WeakPolarHBondContact O-CB 3.48Å; S416-W420 PolarHBondContact O-N 3.11Å
417	V	93.6	Very high	88.7	Confident	77 Å²	77	48.6 Å²	48.6	47%	0.467	26%	0.264	S	S	.	.	H	α-helix	trans	-61.1	-40.6	178.6	167.8	0	0	0	0	112.3	L413 D415 L421	L413-V417 HydrophobicContact CD1-CG2 4.02Å; L413-V417 HydrophobicContact CG-CG2 4.32Å; L413-V417 VanDerWaalsContact O-CB 3.27Å; L413-V417 WeakPolarHBondContact O-CB 3.5Å; L413-V417 WeakPolarHBondContact O-CG2 3.38Å; L413-V417 PolarHBondContact O-N 3.36Å; D415-V417 PolarHBondContact O-N 2.74Å; V417-L421 WeakPolarHBondContact O-CB 3.3Å; V417-L421 PolarHBondContact O-N 3.23Å
418	F	95.9	Very high	90.7	Very high	54 Å²	54	44.8 Å²	44.8	24%	0.237	25%	0.253	C	S	.	.	H	α-helix	trans	-70.7	-38.3	178.1	-76.1	6	0	0	0	112.3	P382 F383 L386 L414 D415 S416 G422	P382-F418 VanDerWaalsContact C-CD2 3.47Å; P382-F418 HydrophobicContact CB-CB 4.4Å; P382-F418 HydrophobicContact CB-CD1 3.81Å; P382-F418 HydrophobicContact CB-CD2 3.67Å; P382-F418 HydrophobicContact CB-CE1 3.88Å; P382-F418 HydrophobicContact CB-CE2 3.75Å; P382-F418 HydrophobicContact CB-CG 3.7Å; P382-F418 HydrophobicContact CB-CZ 3.85Å; P382-F418 VanDerWaalsContact O-CD2 3.26Å; P382-F418 WeakPolarHBondContact O-CD2 3.34Å; F383-F418 HydrophobicContact CB-CB 4.29Å; L386-F418 HydrophobicContact CB-CD2 4.09Å; L386-F418 HydrophobicContact CD2-CD2 3.96Å; L414-F418 HydrophobicContact CD1-CD1 4.21Å; L414-F418 HydrophobicContact CD1-CE1 3.62Å; L414-F418 HydrophobicContact CD1-CE2 4.07Å; L414-F418 HydrophobicContact CD1-CZ 3.55Å; L414-F418 HydrophobicContact CG-CD2 4.49Å; L414-F418 HydrophobicContact CG-CE1 4.45Å; L414-F418 HydrophobicContact CG-CE2 4.2Å; L414-F418 HydrophobicContact CG-CZ 4.18Å; L414-F418 WeakPolarHBondContact O-CB 3.29Å; L414-F418 WeakPolarHBondContact O-CG 3.43Å; L414-F418 PolarHBondContact O-N 3.03Å; D415-F418 PolarHBondContact O-N 3Å; S416-F418 VanDerWaalsContact C-N 3.35Å; S416-F418 PolarHBondContact O-N 2.74Å; F418-G422 PolarHBondContact O-N 3.47Å
419	L	94.2	Very high	92.1	Very high	19 Å²	19	44 Å²	44	10%	0.099	25%	0.247	C	C	.	.	H	α-helix	trans	-63.6	-51.5	174.8	-176	67.4	0	0	0	111.5	F383 D415 S416 L421 G422 Y423	F383-L419 HydrophobicContact CD2-CB 4.24Å; F383-L419 HydrophobicContact CD2-CD1 4.1Å; F383-L419 HydrophobicContact CE2-CB 4.34Å; F383-L419 HydrophobicContact CE2-CD1 3.67Å; F383-L419 HydrophobicContact CZ-CD1 4.02Å; D415-L419 WeakPolarHBondContact O-CB 3.18Å; D415-L419 PolarHBondContact O-N 2.87Å; S416-L419 PolarHBondContact O-N 3.1Å; L419-L421 VanDerWaalsContact C-N 3.31Å; L419-L421 PolarHBondContact O-N 3.22Å; L419-G422 WeakPolarHBondContact O-CA 3.38Å; L419-G422 PolarHBondContact O-N 2.63Å; L419-Y423 HydrophobicContact CD1-CE1 4.31Å; L419-Y423 HydrophobicContact CD1-CE2 3.99Å; L419-Y423 HydrophobicContact CD2-CE2 3.91Å; L419-Y423 HydrophobicContact CG-CD2 4.23Å; L419-Y423 HydrophobicContact CG-CE2 3.56Å; L419-Y423 PolarHBondContact O-N 3.32Å; L419-Y423 VanDerWaalsContact O-N 3.07Å
420	W	96.2	Very high	93.3	Very high	12 Å²	12	37.8 Å²	37.8	5%	0.045	21%	0.214	C	C	.	.	H	α-helix	trans	-64.6	-32.6	178.3	-80	101.2	0	0	0	113.2	F57 I60 T104 A107 A108 D111 S416 G422 Y423 V424	F57-W420 HydrophobicContact CB-CH2 3.94Å; F57-W420 HydrophobicContact CB-CZ2 4.43Å; F57-W420 HydrophobicContact CB-CZ3 4.42Å; F57-W420 AromaticContact CD1-CD2 3.84Å; F57-W420 HydrophobicContact CD1-CD2 3.84Å; F57-W420 AromaticContact CD1-CE2 3.6Å; F57-W420 AromaticContact CD1-CE3 3.89Å; F57-W420 HydrophobicContact CD1-CE3 3.89Å; F57-W420 AromaticContact CD1-CH2 3.52Å; F57-W420 HydrophobicContact CD1-CH2 3.52Å; F57-W420 AromaticContact CD1-CZ2 3.45Å; F57-W420 HydrophobicContact CD1-CZ2 3.45Å; F57-W420 VanDerWaalsContact CD1-CZ2 3.45Å; F57-W420 AromaticContact CD1-CZ3 3.73Å; F57-W420 HydrophobicContact CD1-CZ3 3.73Å; F57-W420 HydrophobicContact CD2-CH2 4.27Å; F57-W420 AromaticContact CD2-CZ2 3.91Å; F57-W420 HydrophobicContact CD2-CZ2 3.91Å; F57-W420 AromaticContact CE1-CD1 3.9Å; F57-W420 AromaticContact CE1-CD2 3.54Å; F57-W420 HydrophobicContact CE1-CD2 3.54Å; F57-W420 AromaticContact CE1-CE2 3.18Å; F57-W420 HydrophobicContact CE1-CE3 4.07Å; F57-W420 HydrophobicContact CE1-CG 4.02Å; F57-W420 HydrophobicContact CE1-CH2 4.03Å; F57-W420 AromaticContact CE1-CZ2 3.48Å; F57-W420 HydrophobicContact CE1-CZ2 3.48Å; F57-W420 VanDerWaalsContact CE1-CZ2 3.48Å; F57-W420 HydrophobicContact CE1-CZ3 4.29Å; F57-W420 AromaticContact CE1-NE1 3.42Å; F57-W420 AromaticContact CE2-CZ2 3.91Å; F57-W420 HydrophobicContact CE2-CZ2 3.91Å; F57-W420 AromaticContact CG-CH2 3.66Å; F57-W420 HydrophobicContact CG-CH2 3.66Å; F57-W420 AromaticContact CG-CZ2 3.68Å; F57-W420 HydrophobicContact CG-CZ2 3.68Å; F57-W420 HydrophobicContact CG-CZ3 4.24Å; F57-W420 HydrophobicContact CZ-CD2 4.3Å; F57-W420 AromaticContact CZ-CE2 3.52Å; F57-W420 AromaticContact CZ-CZ2 3.7Å; F57-W420 HydrophobicContact CZ-CZ2 3.7Å; F57-W420 AromaticContact CZ-NE1 3.41Å; I60-W420 HydrophobicContact CB-CZ3 4.43Å; I60-W420 HydrophobicContact CD1-CE3 3.88Å; I60-W420 HydrophobicContact CD1-CZ3 4.2Å; I60-W420 HydrophobicContact CG2-CZ3 4.16Å; T104-W420 HydrophobicContact CG2-CZ3 4.37Å; A107-W420 HydrophobicContact CB-CZ2 4.26Å; A108-W420 HydrophobicContact CB-CH2 3.99Å; A108-W420 HydrophobicContact CB-CZ2 4.09Å; D111-W420 PolarHBondContact OD2-NE1 3.41Å; S416-W420 WeakPolarHBondContact O-CB 3.48Å; S416-W420 PolarHBondContact O-N 3.11Å; W420-G422 VanDerWaalsContact C-N 3.28Å; W420-G422 PolarHBondContact O-N 3.17Å; W420-Y423 HydrophobicContact CD2-CD2 4.19Å; W420-Y423 HydrophobicContact CE3-CD2 4.09Å; W420-Y423 HydrophobicContact CZ3-CD2 4.37Å; W420-Y423 PolarHBondContact O-N 3.14Å; W420-V424 WeakPolarHBondContact O-CB 3.29Å; W420-V424 VanDerWaalsContact O-CG2 3.26Å; W420-V424 WeakPolarHBondContact O-CG2 3.02Å; W420-V424 PolarHBondContact O-N 2.85Å
421	L	96.8	Very high	93.9	Very high	64 Å²	64	41.7 Å²	41.7	34%	0.335	24%	0.235	S	C	.	.	H	α-helix	trans	-61.6	-38.1	171.9	-178.6	66.2	0	0	0	111.6	C379 P382 V417 L419	C379-L421 HydrophobicContact CB-CG 4.35Å; C379-L421 VanDerWaalsContact CB-O 3.22Å; C379-L421 WeakPolarHBondContact CB-O 3.2Å; C379-L421 PolarHBondContact SG-O 2.84Å; P382-L421 HydrophobicContact CG-CD2 4.08Å; V417-L421 WeakPolarHBondContact O-CB 3.3Å; V417-L421 PolarHBondContact O-N 3.23Å; L419-L421 VanDerWaalsContact C-N 3.31Å; L419-L421 PolarHBondContact O-N 3.22Å
422	G	96.8	Very high	94.3	Very high	0 Å²	0	39 Å²	39	0%	0	22%	0.217	C	C	.	.	H	α-helix	trans	-60.1	-52.1	170.5	0	0	0	0	0	112.3	W380 F418 L419 W420 V424 N425	W380-G422 PolarHBondContact NE1-O 2.87Å; F418-G422 PolarHBondContact O-N 3.47Å; L419-G422 WeakPolarHBondContact O-CA 3.38Å; L419-G422 PolarHBondContact O-N 2.63Å; W420-G422 VanDerWaalsContact C-N 3.28Å; W420-G422 PolarHBondContact O-N 3.17Å; G422-V424 VanDerWaalsContact C-N 3.34Å; G422-V424 PolarHBondContact O-N 3.34Å; G422-N425 VanDerWaalsContact O-CB 3.24Å; G422-N425 WeakPolarHBondContact O-CB 3.43Å; G422-N425 PolarHBondContact O-N 3.33Å; G422-N425 VanDerWaalsContact O-N 3.09Å
423	Y	97.3	Very high	94.9	Very high	0 Å²	0	34.4 Å²	34.4	0%	0	19%	0.186	C	C	.	.	H	α-helix	trans	-62.2	-35.9	178.6	-63.1	-31.6	0	0	0	113.8	V99 V103 T104 A107 D130 W380 L419 W420 N425 S426	V99-Y423 HydrophobicContact CG1-CD1 3.92Å; V103-Y423 HydrophobicContact CG1-CD1 4.48Å; V103-Y423 HydrophobicContact CG1-CE1 3.55Å; V103-Y423 WeakPolarHBondContact CG1-OH 3.48Å; T104-Y423 HydrophobicContact CG2-CD1 4Å; T104-Y423 HydrophobicContact CG2-CD2 3.72Å; T104-Y423 HydrophobicContact CG2-CE2 4.34Å; T104-Y423 HydrophobicContact CG2-CG 3.52Å; A107-Y423 HydrophobicContact CB-CD2 4.42Å; A107-Y423 HydrophobicContact CB-CE2 3.52Å; D130-Y423 WeakPolarHBondContact OD1-CE1 3.31Å; D130-Y423 PolarHBondContact OD2-OH 2.92Å; W380-Y423 HydrophobicContact CH2-CD1 4.24Å; W380-Y423 HydrophobicContact CH2-CE1 4.18Å; W380-Y423 HydrophobicContact CZ2-CD1 4.4Å; L419-Y423 HydrophobicContact CD1-CE1 4.31Å; L419-Y423 HydrophobicContact CD1-CE2 3.99Å; L419-Y423 HydrophobicContact CD2-CE2 3.91Å; L419-Y423 HydrophobicContact CG-CD2 4.23Å; L419-Y423 HydrophobicContact CG-CE2 3.56Å; L419-Y423 PolarHBondContact O-N 3.32Å; L419-Y423 VanDerWaalsContact O-N 3.07Å; W420-Y423 HydrophobicContact CD2-CD2 4.19Å; W420-Y423 HydrophobicContact CE3-CD2 4.09Å; W420-Y423 HydrophobicContact CZ3-CD2 4.37Å; W420-Y423 PolarHBondContact O-N 3.14Å; Y423-N425 PolarHBondContact O-N 2.73Å; Y423-N425 VanDerWaalsContact O-N 3.15Å; Y423-S426 PolarHBondContact O-N 3.35Å; Y423-S426 VanDerWaalsContact O-N 3.1Å
424	V	96.9	Very high	95.2	Very high	36 Å²	36	31 Å²	31	22%	0.218	17%	0.171	C	C	.	.	H	α-helix	trans	-58	-27	174.7	163.3	0	0	0	0	112.1	I60 W420 G422 S426 A427 L428	I60-V424 HydrophobicContact CD1-CG2 3.59Å; I60-V424 HydrophobicContact CG1-CG2 4.18Å; W420-V424 WeakPolarHBondContact O-CB 3.29Å; W420-V424 VanDerWaalsContact O-CG2 3.26Å; W420-V424 WeakPolarHBondContact O-CG2 3.02Å; W420-V424 PolarHBondContact O-N 2.85Å; G422-V424 VanDerWaalsContact C-N 3.34Å; G422-V424 PolarHBondContact O-N 3.34Å; V424-S426 VanDerWaalsContact C-N 3.26Å; V424-S426 PolarHBondContact O-N 3.05Å; V424-A427 WeakPolarHBondContact O-CB 3.48Å; V424-A427 PolarHBondContact O-N 3.31Å; V424-A427 VanDerWaalsContact O-N 3.1Å; V424-L428 HydrophobicContact CG1-CD1 4.14Å; V424-L428 HydrophobicContact CG1-CG 4.06Å; V424-L428 WeakPolarHBondContact O-CG 3.36Å; V424-L428 PolarHBondContact O-N 3.33Å
425	N	97.6	Very high	95.4	Very high	0 Å²	0	32.7 Å²	32.7	0%	0	18%	0.183	C	C	.	.	H	α-helix	trans	-58.3	-37.2	176	-177.1	76.7	0	0	0	113	S375 F376 C379 G422 Y423 A427 L428 N429	S375-N425 WeakPolarHBondContact CB-OD1 3.47Å; S375-N425 PolarHBondContact OG-OD1 2.92Å; F376-N425 VanDerWaalsContact CA-OD1 3.26Å; F376-N425 WeakPolarHBondContact CA-OD1 3.01Å; F376-N425 WeakPolarHBondContact CD2-ND2 3.05Å; F376-N425 PolarHBondContact N-OD1 3.01Å; C379-N425 HydrophobicContact CB-CB 3.78Å; G422-N425 VanDerWaalsContact O-CB 3.24Å; G422-N425 WeakPolarHBondContact O-CB 3.43Å; G422-N425 PolarHBondContact O-N 3.33Å; G422-N425 VanDerWaalsContact O-N 3.09Å; Y423-N425 PolarHBondContact O-N 2.73Å; Y423-N425 VanDerWaalsContact O-N 3.15Å; N425-A427 VanDerWaalsContact C-N 3.27Å; N425-A427 PolarHBondContact O-N 2.91Å; N425-L428 PolarHBondContact O-N 3.35Å; N425-L428 VanDerWaalsContact O-N 3.09Å; N425-N429 PolarHBondContact O-N 3.36Å
426	S	97.9	Very high	95.6	Very high	2 Å²	2	35 Å²	35	1%	0.014	19%	0.192	C	C	.	.	H	α-helix	trans	-66.4	-28.8	179	-63.4	0	0	0	0	112.3	N68 D96 Y423 V424 P430	N68-S426 PolarHBondContact ND2-O 3.31Å; D96-S426 WeakPolarHBondContact OD1-CB 3.24Å; D96-S426 PolarHBondContact OD1-OG 3Å; Y423-S426 PolarHBondContact O-N 3.35Å; Y423-S426 VanDerWaalsContact O-N 3.1Å; V424-S426 VanDerWaalsContact C-N 3.26Å; V424-S426 PolarHBondContact O-N 3.05Å; S426-P430 WeakPolarHBondContact O-CD 3.44Å
427	A	97.1	Very high	95.7	Very high	10 Å²	10	34.3 Å²	34.3	8%	0.083	19%	0.187	C	C	.	.	H	α-helix	trans	-77.1	-32.3	169.4	0	0	0	0	0	113.2	V424 N425 N429	V424-A427 WeakPolarHBondContact O-CB 3.48Å; V424-A427 PolarHBondContact O-N 3.31Å; V424-A427 VanDerWaalsContact O-N 3.1Å; N425-A427 VanDerWaalsContact C-N 3.27Å; N425-A427 PolarHBondContact O-N 2.91Å; A427-N429 PolarHBondContact O-N 2.87Å
428	L	97.4	Very high	95.5	Very high	57 Å²	57	34.1 Å²	34.1	30%	0.298	19%	0.188	S	C	.	.	H	α-helix	trans	-68.2	-32	179.8	-70.1	176.8	0	0	0	113.1	V424 N425 L431 I432	V424-L428 HydrophobicContact CG1-CD1 4.14Å; V424-L428 HydrophobicContact CG1-CG 4.06Å; V424-L428 WeakPolarHBondContact O-CG 3.36Å; V424-L428 PolarHBondContact O-N 3.33Å; N425-L428 PolarHBondContact O-N 3.35Å; N425-L428 VanDerWaalsContact O-N 3.09Å; L428-L431 HydrophobicContact CD2-CD1 4.47Å; L428-L431 WeakPolarHBondContact O-CB 3.04Å; L428-L431 PolarHBondContact O-N 3.18Å; L428-L431 VanDerWaalsContact O-N 3.11Å; L428-I432 HydrophobicContact CB-CD1 4.23Å; L428-I432 VanDerWaalsContact O-CG1 3.32Å; L428-I432 WeakPolarHBondContact O-CG1 3.46Å; L428-I432 PolarHBondContact O-N 3Å
429	N	96.3	Very high	95.3	Very high	2 Å²	2	33.3 Å²	33.3	1%	0.011	19%	0.186	C	C	.	.	H	α-helix	trans	-55.7	-54.9	-175.8	-76.7	-14	0	0	0	113.2	D96 N425 A427 L431 I432 Y433	D96-N429 PolarHBondContact OD2-ND2 2.99Å; N425-N429 PolarHBondContact O-N 3.36Å; A427-N429 PolarHBondContact O-N 2.87Å; N429-L431 VanDerWaalsContact C-N 3.31Å; N429-L431 PolarHBondContact O-N 3.34Å; N429-I432 PolarHBondContact O-N 3.01Å; N429-Y433 HydrophobicContact CB-CE2 4.33Å; N429-Y433 WeakPolarHBondContact O-CD2 3.42Å; N429-Y433 PolarHBondContact O-N 2.93Å; N429-Y433 VanDerWaalsContact O-N 3.08Å
430	P	96.6	Very high	95.3	Very high	8 Å²	8	32.5 Å²	32.5	5%	0.052	18%	0.182	C	C	.	.	H	α-helix	trans	-53.5	-41.9	171.6	-28.3	34.9	0	0	0	114.2	G67 N68 V71 S426 Y433 T434	G67-P430 WeakPolarHBondContact O-CG 3.36Å; N68-P430 WeakPolarHBondContact OD1-CG 3.48Å; V71-P430 HydrophobicContact CG2-CB 4.22Å; V71-P430 HydrophobicContact CG2-CG 4.08Å; S426-P430 WeakPolarHBondContact O-CD 3.44Å; P430-Y433 PolarHBondContact O-N 2.99Å; P430-T434 WeakPolarHBondContact O-CG2 3.42Å; P430-T434 PolarHBondContact O-N 2.69Å
431	L	96	Very high	95.2	Very high	101 Å²	101	33.6 Å²	33.6	53%	0.529	19%	0.194	S	C	.	.	H	α-helix	trans	-64.8	-43.9	179.6	-62.4	176.1	0	0	0	111.5	L428 N429 Y433 T434 V435	L428-L431 HydrophobicContact CD2-CD1 4.47Å; L428-L431 WeakPolarHBondContact O-CB 3.04Å; L428-L431 PolarHBondContact O-N 3.18Å; L428-L431 VanDerWaalsContact O-N 3.11Å; N429-L431 VanDerWaalsContact C-N 3.31Å; N429-L431 PolarHBondContact O-N 3.34Å; L431-Y433 VanDerWaalsContact C-N 3.27Å; L431-Y433 PolarHBondContact O-N 3.3Å; L431-T434 PolarHBondContact O-N 3.28Å; L431-T434 VanDerWaalsContact O-N 3.14Å; L431-T434 PolarHBondContact O-OG1 3.27Å; L431-V435 PolarHBondContact O-N 2.71Å; L431-V435 VanDerWaalsContact O-N 3.11Å
432	I	96.1	Very high	95.1	Very high	16 Å²	16	37.7 Å²	37.7	8%	0.082	21%	0.209	C	C	.	.	H	α-helix	trans	-60.4	-38.9	174.9	-66.1	163.2	0	0	0	110.5	T368 I371 V372 S375 L428 N429 F436	T368-I432 HydrophobicContact CG2-CG2 4.37Å; I371-I432 HydrophobicContact CB-CG2 4.24Å; I371-I432 HydrophobicContact CG2-CD1 4.28Å; I371-I432 HydrophobicContact CG2-CG1 4.28Å; I371-I432 HydrophobicContact CG2-CG2 3.76Å; V372-I432 HydrophobicContact CG2-CB 4.16Å; V372-I432 HydrophobicContact CG2-CD1 4.41Å; V372-I432 HydrophobicContact CG2-CG2 3.5Å; S375-I432 WeakPolarHBondContact OG-CD1 3.3Å; L428-I432 HydrophobicContact CB-CD1 4.23Å; L428-I432 VanDerWaalsContact O-CG1 3.32Å; L428-I432 WeakPolarHBondContact O-CG1 3.46Å; L428-I432 PolarHBondContact O-N 3Å; N429-I432 PolarHBondContact O-N 3.01Å; I432-F436 HydrophobicContact CG2-CD2 3.99Å; I432-F436 WeakPolarHBondContact O-CB 3.23Å; I432-F436 PolarHBondContact O-N 3.29Å
433	Y	94.5	Very high	95	Very high	4 Å²	4	37.8 Å²	37.8	2%	0.016	21%	0.209	C	C	.	.	H	α-helix	trans	-66.5	-39	174.5	-59.9	-42.4	0	0	0	113.1	V71 I89 T368 V372 N429 P430 L431 S437 F440	V71-Y433 HydrophobicContact CG1-CE2 4.41Å; V71-Y433 HydrophobicContact CG2-CD2 3.81Å; V71-Y433 HydrophobicContact CG2-CE2 4.21Å; I89-Y433 HydrophobicContact CG2-CE1 4.32Å; I89-Y433 HydrophobicContact CG2-CE2 3.91Å; T368-Y433 HydrophobicContact CG2-CD1 4.24Å; V372-Y433 HydrophobicContact CG2-CD1 4.43Å; V372-Y433 HydrophobicContact CG2-CE1 3.72Å; N429-Y433 HydrophobicContact CB-CE2 4.33Å; N429-Y433 WeakPolarHBondContact O-CD2 3.42Å; N429-Y433 PolarHBondContact O-N 2.93Å; N429-Y433 VanDerWaalsContact O-N 3.08Å; P430-Y433 PolarHBondContact O-N 2.99Å; L431-Y433 VanDerWaalsContact C-N 3.27Å; L431-Y433 PolarHBondContact O-N 3.3Å; Y433-S437 WeakPolarHBondContact O-CA 3.48Å; Y433-S437 WeakPolarHBondContact O-CB 3.27Å; Y433-S437 PolarHBondContact O-N 3.02Å; Y433-F440 HydrophobicContact CD1-CD2 4.12Å; Y433-F440 HydrophobicContact CD1-CE2 4.21Å; Y433-F440 HydrophobicContact CG-CD2 4.01Å; Y433-F440 HydrophobicContact CG-CE2 4.25Å; Y433-F440 HydrophobicContact CG-CG 4.5Å
434	T	94	Very high	94.9	Very high	59 Å²	59	38.4 Å²	38.4	36%	0.362	21%	0.212	S	C	.	.	H	α-helix	trans	-62.4	-42	176.1	69	0	0	0	0	112.5	P430 L431 A441 F444	P430-T434 WeakPolarHBondContact O-CG2 3.42Å; P430-T434 PolarHBondContact O-N 2.69Å; L431-T434 PolarHBondContact O-N 3.28Å; L431-T434 VanDerWaalsContact O-N 3.14Å; L431-T434 PolarHBondContact O-OG1 3.27Å; T434-A441 WeakPolarHBondContact O-CB 3.14Å; T434-F444 HydrophobicContact CG2-CD2 3.59Å; T434-F444 HydrophobicContact CG2-CE2 3.78Å
435	V	94.1	Very high	94.7	Very high	104 Å²	104	44 Å²	44	63%	0.63	23%	0.233	S	C	*	.	H	α-helix	trans	-81.5	-43.5	-174.2	176.7	0	0	0	0	111.8	L431	L431-V435 PolarHBondContact O-N 2.71Å; L431-V435 VanDerWaalsContact O-N 3.11Å
436	F	92.7	Very high	94.5	Very high	80 Å²	80	48.6 Å²	48.6	35%	0.351	25%	0.253	S	S	.	.	H	α-helix	trans	-106.4	-14	-168.5	-61.5	-74.5	0	0	0	115	T368 I371 I432 P438	T368-F436 HydrophobicContact CG2-CB 3.93Å; T368-F436 PolarHBondContact OG1-O 3.03Å; T368-F436 VanDerWaalsContact OG1-O 3.13Å; I371-F436 HydrophobicContact CD1-CD1 3.83Å; I371-F436 HydrophobicContact CD1-CD2 4.02Å; I371-F436 HydrophobicContact CD1-CE1 3.95Å; I371-F436 HydrophobicContact CD1-CE2 4.12Å; I371-F436 HydrophobicContact CD1-CG 3.87Å; I371-F436 HydrophobicContact CD1-CZ 4.08Å; I371-F436 HydrophobicContact CG2-CD2 4.41Å; I371-F436 HydrophobicContact CG2-CE2 4.29Å; I432-F436 HydrophobicContact CG2-CD2 3.99Å; I432-F436 WeakPolarHBondContact O-CB 3.23Å; I432-F436 PolarHBondContact O-N 3.29Å; F436-P438 WeakPolarHBondContact O-CD 3.38Å
437	S	91.2	Very high	94.3	Very high	15 Å²	15	49.9 Å²	49.9	11%	0.105	26%	0.26	C	S	.	.			trans	-111	100.5	174.1	-176.3	0	0	0	0	112.5	Y433 D439 F440 A441	Y433-S437 WeakPolarHBondContact O-CA 3.48Å; Y433-S437 WeakPolarHBondContact O-CB 3.27Å; Y433-S437 PolarHBondContact O-N 3.02Å; S437-D439 PolarHBondContact O-N 3.15Å; S437-D439 VanDerWaalsContact O-N 3.08Å; S437-F440 PolarHBondContact O-N 3.44Å; S437-F440 VanDerWaalsContact O-N 3.15Å; S437-F440 PolarHBondContact OG-N 3.49Å; S437-A441 WeakPolarHBondContact O-CB 3.43Å; S437-A441 PolarHBondContact O-N 2.95Å
438	P	90.5	Very high	94	Very high	74 Å²	74	53.5 Å²	53.5	48%	0.481	28%	0.277	S	S	.	.	H	α-helix	trans	-60	-20	175.5	-25.4	34.9	0	0	0	114.7	F436 K442	F436-P438 WeakPolarHBondContact O-CD 3.38Å; P438-K442 WeakPolarHBondContact O-CD 3.41Å; P438-K442 WeakPolarHBondContact O-CG 3.24Å; P438-K442 PolarHBondContact O-N 3.4Å
439	D	91.3	Very high	93.7	Very high	36 Å²	36	53.9 Å²	53.9	19%	0.193	28%	0.282	C	S	.	.	H	α-helix	trans	-76.7	-44.6	176.7	-66	-28.3	0	0	0	110.4	L81 Y86 R361 S437 A443	L81-D439 HydrophobicContact CD2-CB 3.88Å; Y86-D439 PolarHBondContact OH-OD2 3.29Å; R361-D439 IonicContact CZ-OD2 2.74Å; R361-D439 IonicContact NE-OD2 2.67Å; R361-D439 PolarHBondContact NE-OD2 3.18Å; R361-D439 IonicContact NH2-OD1 3.35Å; R361-D439 IonicContact NH2-OD2 3.89Å; R361-D439 PolarHBondContact NH2-OD2 3.38Å; S437-D439 PolarHBondContact O-N 3.15Å; S437-D439 VanDerWaalsContact O-N 3.08Å; D439-A443 PolarHBondContact O-N 3.03Å
440	F	93.8	Very high	93.4	Very high	2 Å²	2	59.9 Å²	59.9	1%	0.009	31%	0.308	C	S	.	.	H	α-helix	trans	-67.9	-45.3	173.3	-83.5	-66.5	0	0	0	112.1	V71 A74 V75 L81 Y86 I89 Y433 S437 K442 A443 F444	V71-F440 HydrophobicContact CG1-CE1 4.16Å; V71-F440 HydrophobicContact CG1-CZ 4.36Å; A74-F440 HydrophobicContact CB-CD1 4.13Å; A74-F440 HydrophobicContact CB-CE1 4.27Å; V75-F440 HydrophobicContact CG2-CE1 3.91Å; V75-F440 HydrophobicContact CG2-CZ 4.02Å; L81-F440 HydrophobicContact CD1-CD1 3.66Å; L81-F440 HydrophobicContact CD1-CE1 3.78Å; L81-F440 HydrophobicContact CD1-CG 4.39Å; L81-F440 HydrophobicContact CD2-CD1 4.48Å; L81-F440 HydrophobicContact CD2-CE1 4.46Å; Y86-F440 AromaticContact CD1-CE2 3.87Å; Y86-F440 HydrophobicContact CD1-CE2 3.87Å; Y86-F440 AromaticContact CD1-CZ 3.78Å; Y86-F440 HydrophobicContact CD1-CZ 3.78Å; Y86-F440 HydrophobicContact CE1-CD2 4.38Å; Y86-F440 AromaticContact CE1-CE2 3.63Å; Y86-F440 HydrophobicContact CE1-CE2 3.63Å; Y86-F440 AromaticContact CE1-CZ 3.98Å; Y86-F440 HydrophobicContact CE1-CZ 3.98Å; I89-F440 HydrophobicContact CD1-CE2 4.36Å; I89-F440 HydrophobicContact CG2-CE2 4.19Å; I89-F440 HydrophobicContact CG2-CZ 3.88Å; Y433-F440 HydrophobicContact CD1-CD2 4.12Å; Y433-F440 HydrophobicContact CD1-CE2 4.21Å; Y433-F440 HydrophobicContact CG-CD2 4.01Å; Y433-F440 HydrophobicContact CG-CE2 4.25Å; Y433-F440 HydrophobicContact CG-CG 4.5Å; S437-F440 PolarHBondContact O-N 3.44Å; S437-F440 VanDerWaalsContact O-N 3.15Å; S437-F440 PolarHBondContact OG-N 3.49Å; F440-K442 PolarHBondContact O-N 3.16Å; F440-A443 WeakPolarHBondContact O-CA 3.36Å; F440-A443 WeakPolarHBondContact O-CB 3.06Å; F440-A443 PolarHBondContact O-N 3.24Å; F440-F444 HydrophobicContact CB-CD2 4.47Å; F440-F444 HydrophobicContact CB-CE2 4Å; F440-F444 HydrophobicContact CB-CZ 4.13Å; F440-F444 AromaticContact CD1-CE1 4Å; F440-F444 HydrophobicContact CD1-CE1 4Å; F440-F444 HydrophobicContact CD1-CE2 4.5Å; F440-F444 AromaticContact CD1-CZ 3.79Å; F440-F444 HydrophobicContact CD1-CZ 3.79Å; F440-F444 HydrophobicContact CG-CZ 4.27Å; F440-F444 WeakPolarHBondContact O-CG 3.27Å; F440-F444 PolarHBondContact O-N 3.46Å
441	A	94.2	Very high	92.9	Very high	36 Å²	36	63.6 Å²	63.6	30%	0.298	33%	0.331	S	S	.	.	H	α-helix	trans	-54.8	-39.9	178.4	0	0	0	0	0	112.8	T434 S437 K445	T434-A441 WeakPolarHBondContact O-CB 3.14Å; S437-A441 WeakPolarHBondContact O-CB 3.43Å; S437-A441 PolarHBondContact O-N 2.95Å; A441-K445 WeakPolarHBondContact O-CB 3.49Å; A441-K445 PolarHBondContact O-N 3.08Å; A441-K445 VanDerWaalsContact O-N 3.08Å
442	K	94.2	Very high	92.5	Very high	150 Å²	150	64.6 Å²	64.6	65%	0.652	34%	0.336	S	S	*	.	H	α-helix	trans	-68	-43	173.7	-75.2	173	-177.1	-177.3	0	112.6	P438 F440 K446	P438-K442 WeakPolarHBondContact O-CD 3.41Å; P438-K442 WeakPolarHBondContact O-CG 3.24Å; P438-K442 PolarHBondContact O-N 3.4Å; F440-K442 PolarHBondContact O-N 3.16Å; K442-K446 VanDerWaalsContact O-CB 3.3Å; K442-K446 WeakPolarHBondContact O-CB 3.47Å; K442-K446 PolarHBondContact O-N 3.27Å
443	A	94.6	Very high	92	Very high	1 Å²	1	69.2 Å²	69.2	1%	0.008	36%	0.36	C	S	.	.	H	α-helix	trans	-63.2	-46.9	178.6	0	0	0	0	0	111.3	A74 E78 L81 D439 F440 K446 I447	A74-A443 HydrophobicContact CB-CB 3.86Å; E78-A443 HydrophobicContact CB-CB 4.08Å; E78-A443 HydrophobicContact CG-CB 4.14Å; L81-A443 HydrophobicContact CD1-CB 3.57Å; D439-A443 PolarHBondContact O-N 3.03Å; F440-A443 WeakPolarHBondContact O-CA 3.36Å; F440-A443 WeakPolarHBondContact O-CB 3.06Å; F440-A443 PolarHBondContact O-N 3.24Å; A443-K446 WeakPolarHBondContact O-CB 3.48Å; A443-K446 PolarHBondContact O-N 3.25Å; A443-I447 WeakPolarHBondContact O-CG1 3.3Å; A443-I447 PolarHBondContact O-N 3.09Å
444	F	95.2	Very high	91.5	Very high	13 Å²	13	79.5 Å²	79.5	6%	0.057	40%	0.399	C	S	.	.	H	α-helix	trans	-61.2	-47.2	176.3	-60.7	-25.4	0	0	0	112	L70 V71 A74 T434 F440 K446 I447 L448	L70-F444 HydrophobicContact CB-CD1 4.31Å; L70-F444 HydrophobicContact CB-CE1 4.2Å; L70-F444 WeakPolarHBondContact O-CE1 3.43Å; V71-F444 HydrophobicContact CG2-CE1 4.47Å; V71-F444 HydrophobicContact CG2-CZ 3.86Å; A74-F444 HydrophobicContact CB-CD1 3.85Å; A74-F444 HydrophobicContact CB-CE1 3.56Å; T434-F444 HydrophobicContact CG2-CD2 3.59Å; T434-F444 HydrophobicContact CG2-CE2 3.78Å; F440-F444 HydrophobicContact CB-CD2 4.47Å; F440-F444 HydrophobicContact CB-CE2 4Å; F440-F444 HydrophobicContact CB-CZ 4.13Å; F440-F444 AromaticContact CD1-CE1 4Å; F440-F444 HydrophobicContact CD1-CE1 4Å; F440-F444 HydrophobicContact CD1-CE2 4.5Å; F440-F444 AromaticContact CD1-CZ 3.79Å; F440-F444 HydrophobicContact CD1-CZ 3.79Å; F440-F444 HydrophobicContact CG-CZ 4.27Å; F440-F444 WeakPolarHBondContact O-CG 3.27Å; F440-F444 PolarHBondContact O-N 3.46Å; F444-K446 VanDerWaalsContact C-N 3.3Å; F444-K446 PolarHBondContact O-N 3.26Å; F444-I447 PolarHBondContact O-N 3.09Å; F444-L448 WeakPolarHBondContact O-CB 3.21Å; F444-L448 WeakPolarHBondContact O-CG 3.42Å; F444-L448 PolarHBondContact O-N 3.49Å
445	K	94	Very high	90.6	Very high	153 Å²	153	81.6 Å²	81.6	67%	0.665	42%	0.416	S	S	*	.	H	α-helix	trans	-56.3	-45.4	174.3	-176.6	171.6	-179	173.1	0	111.4	A441 T449	A441-K445 WeakPolarHBondContact O-CB 3.49Å; A441-K445 PolarHBondContact O-N 3.08Å; A441-K445 VanDerWaalsContact O-N 3.08Å; K445-T449 VanDerWaalsContact O-CB 3.3Å; K445-T449 WeakPolarHBondContact O-CB 3.32Å; K445-T449 PolarHBondContact O-N 3.08Å; K445-T449 PolarHBondContact O-OG1 3.03Å
446	K	93.7	Very high	89	Confident	98 Å²	98	89.4 Å²	89.4	43%	0.426	43%	0.434	S	S	.	.	H	α-helix	trans	-64.2	-38.8	178.8	179.1	179.8	172.2	-176	0	113	E78 K442 A443 F444 K450	E78-K446 IonicContact OE1-NZ 2.74Å; E78-K446 WeakPolarHBondContact OE2-CD 3.49Å; E78-K446 WeakPolarHBondContact OE2-CE 3.08Å; E78-K446 IonicContact OE2-NZ 3.8Å; E78-K446 PolarHBondContact OE2-NZ 2.76Å; K442-K446 VanDerWaalsContact O-CB 3.3Å; K442-K446 WeakPolarHBondContact O-CB 3.47Å; K442-K446 PolarHBondContact O-N 3.27Å; A443-K446 WeakPolarHBondContact O-CB 3.48Å; A443-K446 PolarHBondContact O-N 3.25Å; F444-K446 VanDerWaalsContact C-N 3.3Å; F444-K446 PolarHBondContact O-N 3.26Å; K446-K450 WeakPolarHBondContact O-CB 3.18Å; K446-K450 VanDerWaalsContact O-CG 3.31Å; K446-K450 WeakPolarHBondContact O-CG 3.48Å; K446-K450 PolarHBondContact O-N 3.27Å; K446-K450 VanDerWaalsContact O-N 3.15Å
447	I	92.3	Very high	88.8	Confident	29 Å²	29	89.9 Å²	89.9	15%	0.149	44%	0.438	C	S	.	.	H	α-helix	trans	-67.2	-55.4	175.9	-70.8	166.1	0	0	0	109.7	L70 A73 A74 A443 F444 T449 K450 T451	L70-I447 HydrophobicContact CD2-CG2 3.92Å; A73-I447 HydrophobicContact CB-CD1 4.29Å; A74-I447 HydrophobicContact CB-CD1 3.97Å; A443-I447 WeakPolarHBondContact O-CG1 3.3Å; A443-I447 PolarHBondContact O-N 3.09Å; F444-I447 PolarHBondContact O-N 3.09Å; I447-T449 PolarHBondContact O-N 3.23Å; I447-K450 WeakPolarHBondContact O-CA 3.4Å; I447-K450 WeakPolarHBondContact O-CB 3.47Å; I447-K450 PolarHBondContact O-N 3.36Å; I447-T451 PolarHBondContact O-N 3.41Å; I447-T451 PolarHBondContact O-OG1 3Å
448	L	91.3	Very high	88.7	Confident	86 Å²	86	93.8 Å²	93.8	45%	0.45	46%	0.456	S	S	.	.	H	α-helix	trans	-58.6	-44.6	-178.5	-67.1	170.9	0	0	0	111.8	L70 F444 K450 T451 L452	L70-L448 HydrophobicContact CD1-CD2 4.46Å; L70-L448 HydrophobicContact CD2-CD2 4.38Å; F444-L448 WeakPolarHBondContact O-CB 3.21Å; F444-L448 WeakPolarHBondContact O-CG 3.42Å; F444-L448 PolarHBondContact O-N 3.49Å; L448-K450 VanDerWaalsContact C-N 3.34Å; L448-K450 PolarHBondContact O-N 3.48Å; L448-T451 PolarHBondContact O-N 3.44Å; L448-L452 WeakPolarHBondContact O-CB 3.28Å; L448-L452 VanDerWaalsContact O-CG 3.27Å; L448-L452 WeakPolarHBondContact O-CG 3.34Å; L448-L452 PolarHBondContact O-N 3.46Å
449	T	92	Very high	88.6	Confident	64 Å²	64	94.9 Å²	94.9	39%	0.393	45%	0.454	S	S	.	.	H	α-helix	trans	-61.3	-39.8	174.3	-61.5	0	0	0	0	112.1	K445 I447 L453	K445-T449 VanDerWaalsContact O-CB 3.3Å; K445-T449 WeakPolarHBondContact O-CB 3.32Å; K445-T449 PolarHBondContact O-N 3.08Å; K445-T449 PolarHBondContact O-OG1 3.03Å; I447-T449 PolarHBondContact O-N 3.23Å; T449-L453 HydrophobicContact CG2-CD1 3.77Å; T449-L453 HydrophobicContact CG2-CG 4.3Å; T449-L453 VanDerWaalsContact O-CB 3.29Å; T449-L453 WeakPolarHBondContact O-CB 3.47Å; T449-L453 WeakPolarHBondContact O-CG 3.34Å; T449-L453 PolarHBondContact O-N 3.29Å
450	K	89.6	Confident	88.5	Confident	128 Å²	128	98.4 Å²	98.4	56%	0.557	47%	0.47	S	S	*	.	H	α-helix	trans	-67.8	-37.3	175.9	-80.9	-174.3	171.6	-155.2	0	113.3	K446 I447 L448 R454	K446-K450 WeakPolarHBondContact O-CB 3.18Å; K446-K450 VanDerWaalsContact O-CG 3.31Å; K446-K450 WeakPolarHBondContact O-CG 3.48Å; K446-K450 PolarHBondContact O-N 3.27Å; K446-K450 VanDerWaalsContact O-N 3.15Å; I447-K450 WeakPolarHBondContact O-CA 3.4Å; I447-K450 WeakPolarHBondContact O-CB 3.47Å; I447-K450 PolarHBondContact O-N 3.36Å; L448-K450 VanDerWaalsContact C-N 3.34Å; L448-K450 PolarHBondContact O-N 3.48Å; K450-R454 WeakPolarHBondContact O-CB 3.5Å; K450-R454 WeakPolarHBondContact O-CG 3.46Å; K450-R454 PolarHBondContact O-N 3.36Å; K450-R454 VanDerWaalsContact O-N 3.15Å
451	T	86.5	Confident	88.1	Confident	87 Å²	87	104.4 Å²	104.4	53%	0.534	50%	0.499	S	S	.	.	H	α-helix	trans	-68.3	-46	176.8	-54.9	0	0	0	0	110.6	I447 L448 L453 R454 S455	I447-T451 PolarHBondContact O-N 3.41Å; I447-T451 PolarHBondContact O-OG1 3Å; L448-T451 PolarHBondContact O-N 3.44Å; T451-L453 VanDerWaalsContact C-N 3.33Å; T451-L453 PolarHBondContact O-N 3.36Å; T451-R454 PolarHBondContact O-N 3.21Å; T451-R454 VanDerWaalsContact O-N 3.1Å; T451-S455 PolarHBondContact O-N 3.32Å; T451-S455 VanDerWaalsContact O-N 3.12Å
452	L	86	Confident	87.7	Confident	121 Å²	121	109 Å²	109	63%	0.634	51%	0.512	S	S	*	.	H	α-helix	trans	-63.1	-36.2	176.5	-69	170.4	0	0	0	112.8	L448 R454 S455	L448-L452 WeakPolarHBondContact O-CB 3.28Å; L448-L452 VanDerWaalsContact O-CG 3.27Å; L448-L452 WeakPolarHBondContact O-CG 3.34Å; L448-L452 PolarHBondContact O-N 3.46Å; L452-R454 VanDerWaalsContact C-N 3.31Å; L452-S455 PolarHBondContact O-N 3.2Å
453	L	87.2	Confident	87.3	Confident	113 Å²	113	106.1 Å²	106.1	59%	0.592	50%	0.502	S	S	*	.	T	Hydrogen-bonded Turn	trans	-77.2	-10.8	174.9	-72.1	174	0	0	0	114.4	T449 T451	T449-L453 HydrophobicContact CG2-CD1 3.77Å; T449-L453 HydrophobicContact CG2-CG 4.3Å; T449-L453 VanDerWaalsContact O-CB 3.29Å; T449-L453 WeakPolarHBondContact O-CB 3.47Å; T449-L453 WeakPolarHBondContact O-CG 3.34Å; T449-L453 PolarHBondContact O-N 3.29Å; T451-L453 VanDerWaalsContact C-N 3.33Å; T451-L453 PolarHBondContact O-N 3.36Å
454	R	83.1	Confident	86.7	Confident	220 Å²	220	114.2 Å²	114.2	83%	0.83	54%	0.54	S	S	*	.	T	Hydrogen-bonded Turn	trans	-96.8	-12.6	171.3	-79.6	177	167.8	-167.9	-6.9	113.1	K450 T451 L452	K450-R454 WeakPolarHBondContact O-CB 3.5Å; K450-R454 WeakPolarHBondContact O-CG 3.46Å; K450-R454 PolarHBondContact O-N 3.36Å; K450-R454 VanDerWaalsContact O-N 3.15Å; T451-R454 PolarHBondContact O-N 3.21Å; T451-R454 VanDerWaalsContact O-N 3.1Å; L452-R454 VanDerWaalsContact C-N 3.31Å
455	S	75.4	Confident	86	Confident	103 Å²	103	122.6 Å²	122.6	72%	0.72	58%	0.58	S	S	*	*			trans	-95.7	4.3	175.8	-172.9	0	0	0	0	112.3	T451 L452	T451-S455 PolarHBondContact O-N 3.32Å; T451-S455 VanDerWaalsContact O-N 3.12Å; L452-S455 PolarHBondContact O-N 3.2Å
456	R	61	Low	85.3	Confident	269 Å²	269	119.8 Å²	119.8	100%	1.015	57%	0.573	S	S	*	*			trans	-117.8	0	168.6	-70.2	-177	175.2	-163.2	-2.9	107.7

Retrieved 456 of 456 residues in 188 ms (Link to these results)

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