A0A077Z464_TRITR Loading...

6-phosphofructokinase

AlphaFold DB , UniProt , Accession A0A077Z464, Species TRITR (Trichuris trichiura, Whipworm), Gene n/a, Length 767 aa.

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Site Residue pLDDT pLDDT confidence pLDDT10 pLDDT10 confidence SASA SASA [Ų] SASA10 SASA10 [Ų] RSA RSA unformatted RSA10 RSA10 unformatted Surface Surface10 (not used) Disorder (not used) Disorder Sec. str. Secondary structure Isomer Phi (φ) Psi (ψ) Omega (ω) Chi 1 (χ1) Chi 2 (χ2) Chi 3 (χ3) Chi 4 (χ4) Chi 5 (χ5) Tau (τ) Contacts (colored by PAE) Contact details
1M28.8Very low42Very low235 Ų235157.9 Ų157.9100%1.15878%0.782SS**  0109.60-63-175.7-157.900105.6N3M1-N3 PolarHBondContact O-N 3.09Å
2E29.4Very low46.3Very low199 Ų199145.4 Ų145.493%0.9372%0.721SS**  trans-65.5101.2-177-71.8171.115000109G4E2-G4 PolarHBondContact O-N 3.35Å
3N30.6Very low50.1Low149 Ų149134.2 Ų134.280%0.79767%0.666SS**  trans-71.5112.6161.2-78.7-15.1000106.2M1 E5M1-N3 PolarHBondContact O-N 3.09Å; N3-E5 VanDerWaalsContact C-N 3.32Å; N3-E5 PolarHBondContact O-N 3.35Å
4G27.4Very low53.5Low76 Ų76124.6 Ų124.678%0.78462%0.618SS**  trans-58.497.6169.100000109.2E2 E6E2-G4 PolarHBondContact O-N 3.35Å; G4-E6 PolarHBondContact O-N 3.29Å
5E27.7Very low56.5Low185 Ų185116.3 Ų116.386%0.86458%0.577SS**  trans-65.291.7161.1-74.1-177165.300106.5N3 K7N3-E5 VanDerWaalsContact C-N 3.32Å; N3-E5 PolarHBondContact O-N 3.35Å; E5-K7 PolarHBondContact O-N 3.03Å
6E29.5Very low59.1Low175 Ų175109.1 Ų109.182%0.81854%0.541SS*.  trans-48.1108.5156.3-165.4174.9-15500105.5G4 V8G4-E6 PolarHBondContact O-N 3.29Å; E6-V8 PolarHBondContact O-N 2.9Å
7K32.9Very low61.4Low203 Ų203102.6 Ų102.688%0.88351%0.509SS*.  trans-55.195177.8-94.1-177.5174.2178.50107E5 R9E5-K7 PolarHBondContact O-N 3.03Å; K7-R9 VanDerWaalsContact C-N 3.32Å; K7-R9 PolarHBondContact O-N 3.23Å
8V43.7Very low63.3Low129 Ų12997.3 Ų97.378%0.78248%0.484SS*.  trans-61.7103.5174.8179.50000104.8E6 E10E6-V8 PolarHBondContact O-N 2.9Å; V8-E10 PolarHBondContact O-N 3.33Å
9R55.6Low64.8Low138 Ų13894 Ų9452%0.52148%0.477SS..  trans-55.4124.1-177-169.4167.9168.7-141.1-21.9108.2K7 R11 L147K7-R9 VanDerWaalsContact C-N 3.32Å; K7-R9 PolarHBondContact O-N 3.23Å; R9-R11 PolarHBondContact O-N 2.89Å; R9-L147 VanDerWaalsContact CZ-CG 3.45Å; R9-L147 PolarHBondContact NH1-O 2.92Å; R9-L147 VanDerWaalsContact NH2-C 3.33Å; R9-L147 PolarHBondContact NH2-O 3.43Å
10E70.1Confident66.1Low143 Ų14391.1 Ų91.167%0.66847%0.471SS*.  trans-51.7113.7178.3-85.1-176.6158.500109.2V8 R42V8-E10 PolarHBondContact O-N 3.33Å; E10-R42 WeakPolarHBondContact OE2-CD 3.39Å
11R86.1Confident67.4Low105 Ų10589.5 Ų89.540%0.39646%0.463SS..  trans-87.3133.2176.9-68.4-174.7175.4-177.2-3108.6R9 Y41 R42R9-R11 PolarHBondContact O-N 2.89Å; R11-Y41 HydrophobicContact CB-CD1 3.71Å; R11-Y41 HydrophobicContact CB-CE1 3.46Å; R11-Y41 VanDerWaalsContact CB-CE1 3.46Å; R11-Y41 HydrophobicContact CG-CE1 4.46Å; R11-Y41 WeakPolarHBondContact O-CA 3.5Å; R11-Y41 VanDerWaalsContact O-CD1 3.32Å; R11-Y41 WeakPolarHBondContact O-CD1 3.4Å; R11-R42 PolarHBondContact O-N 3.5Å
12S93.7Very high70.6Confident8 Ų878.3 Ų78.36%0.05641%0.408CS..EExtended strand (participates in β ladder)trans-99.5136.1173.1-53.70000111.1R42 G104 T106S12-R42 CarbonylContact C-O 3.43Å; S12-R42 VanDerWaalsContact CA-O 3.26Å; S12-R42 WeakPolarHBondContact CA-O 3.39Å; S12-G104 WeakPolarHBondContact CB-O 3.46Å; S12-T106 PolarHBondContact O-N 3.39Å
13M95.6Very high73.8Confident0 Ų069 Ų690%037%0.365CS..EExtended strand (participates in β ladder)trans-120.3136.1176.5177.9-176.3-59.600109.9V32 Y41 R42 V43 F44 D107 V109 V316 L319M13-V32 HydrophobicContact SD-CG1 3.8Å; M13-Y41 HydrophobicContact CB-CD1 3.68Å; M13-Y41 HydrophobicContact CB-CE1 4.2Å; M13-Y41 HydrophobicContact CB-CG 4.3Å; M13-Y41 HydrophobicContact CE-CD1 3.95Å; M13-Y41 HydrophobicContact CE-CD2 4.11Å; M13-Y41 HydrophobicContact CE-CE1 3.89Å; M13-Y41 HydrophobicContact CE-CE2 4.06Å; M13-Y41 HydrophobicContact CE-CG 4.05Å; M13-R42 PolarHBondContact N-O 3.05Å; M13-V43 CarbonylContact O-C 3.55Å; M13-V43 WeakPolarHBondContact O-CA 3.28Å; M13-F44 PolarHBondContact O-N 3.33Å; M13-D107 CarbonylContact C-O 3.56Å; M13-D107 VanDerWaalsContact CA-O 3.22Å; M13-D107 WeakPolarHBondContact CA-O 3.46Å; M13-D107 HydrophobicContact CB-CB 4.11Å; M13-D107 HydrophobicContact CE-CB 4.42Å; M13-D107 HydrophobicContact CG-CB 4.15Å; M13-V109 HydrophobicContact SD-CG2 3.97Å; M13-V316 HydrophobicContact CE-CB 4.47Å; M13-V316 HydrophobicContact CE-CG1 4.11Å; M13-V316 HydrophobicContact CE-CG2 4.18Å; M13-V316 HydrophobicContact SD-CG2 4.19Å; M13-L319 HydrophobicContact CE-CB 4.42Å; M13-L319 HydrophobicContact CE-CD1 3.6Å; M13-L319 HydrophobicContact SD-CD1 4.12Å
14G97.7Very high76.9Confident0 Ų061.9 Ų61.90%033%0.328CS..EExtended strand (participates in β ladder)trans-100.3142.3167.800000111.1F44 D107 L108 V109G14-F44 CarbonylContact C-O 3.58Å; G14-F44 WeakPolarHBondContact CA-O 3.31Å; G14-D107 PolarHBondContact N-O 2.94Å; G14-L108 WeakPolarHBondContact O-CA 3.37Å; G14-V109 PolarHBondContact O-N 3.47Å
15V98.4Very high80.3Confident0 Ų058.3 Ų58.30%029%0.29CS..EExtended strand (participates in β ladder)trans-130.3135.8168.359.90000109.9L29 V32 V43 F44 L45 I46 V109 I111V15-L29 HydrophobicContact CB-CD1 4.21Å; V15-L29 HydrophobicContact CG1-CD1 3.54Å; V15-L29 HydrophobicContact CG2-CD1 3.6Å; V15-V32 HydrophobicContact CB-CG1 3.94Å; V15-V32 HydrophobicContact CG1-CG1 4.41Å; V15-V32 HydrophobicContact CG2-CB 4.27Å; V15-V32 HydrophobicContact CG2-CG1 3.95Å; V15-V43 HydrophobicContact CG1-CG1 4.08Å; V15-F44 PolarHBondContact N-O 2.91Å; V15-L45 HydrophobicContact CG1-CD2 3.68Å; V15-I46 PolarHBondContact O-N 3.41Å; V15-V109 WeakPolarHBondContact CA-O 3.33Å; V15-V109 HydrophobicContact CB-CB 4.37Å; V15-V109 HydrophobicContact CG2-CB 4.16Å; V15-V109 HydrophobicContact CG2-CG1 4.36Å; V15-I111 HydrophobicContact CG2-CD1 3.95Å; V15-I111 HydrophobicContact CG2-CG1 4.49Å
16F98.1Very high83.6Confident0 Ų049.5 Ų49.50%025%0.249CC..EExtended strand (participates in β ladder)trans-146.1150.6-177.575.6-79.2000111.9I46 Y50 M53 L108 V109 C110 I111 L120F16-I46 HydrophobicContact CB-CB 3.8Å; F16-I46 HydrophobicContact CB-CD1 4.41Å; F16-I46 HydrophobicContact CB-CG1 4.45Å; F16-Y50 HydrophobicContact CE2-CD1 4.05Å; F16-Y50 HydrophobicContact CE2-CD2 4.32Å; F16-Y50 AromaticContact CE2-CE1 3.67Å; F16-Y50 HydrophobicContact CE2-CE1 3.67Å; F16-Y50 AromaticContact CE2-CE2 3.96Å; F16-Y50 HydrophobicContact CE2-CE2 3.96Å; F16-Y50 HydrophobicContact CE2-CG 4.35Å; F16-Y50 AromaticContact CE2-CZ 3.62Å; F16-Y50 HydrophobicContact CZ-CD1 4.39Å; F16-Y50 AromaticContact CZ-CE1 3.65Å; F16-Y50 HydrophobicContact CZ-CE1 3.65Å; F16-Y50 HydrophobicContact CZ-CE2 4.44Å; F16-Y50 AromaticContact CZ-CZ 3.67Å; F16-M53 HydrophobicContact CD1-CE 3.77Å; F16-M53 HydrophobicContact CD2-CE 4.22Å; F16-M53 HydrophobicContact CE1-CE 3.7Å; F16-M53 HydrophobicContact CE2-CE 4.13Å; F16-M53 HydrophobicContact CG-CE 4.04Å; F16-M53 HydrophobicContact CZ-CE 3.87Å; F16-L108 HydrophobicContact CD1-CD1 3.91Å; F16-L108 HydrophobicContact CD1-CD2 4.49Å; F16-L108 HydrophobicContact CD1-CG 4.15Å; F16-L108 HydrophobicContact CE1-CD1 4.03Å; F16-L108 HydrophobicContact CE1-CD2 3.8Å; F16-L108 HydrophobicContact CE1-CG 3.78Å; F16-V109 WeakPolarHBondContact CD1-O 3.49Å; F16-V109 PolarHBondContact N-O 2.88Å; F16-V109 VanDerWaalsContact N-O 3.12Å; F16-C110 HydrophobicContact CD1-CB 4.42Å; F16-C110 HydrophobicContact CE1-CB 3.6Å; F16-C110 HydrophobicContact CE2-CB 4.37Å; F16-C110 HydrophobicContact CZ-CB 3.58Å; F16-C110 WeakPolarHBondContact CZ-SG 3.34Å; F16-I111 PolarHBondContact O-N 3.41Å; F16-L120 HydrophobicContact CE1-CD1 4.08Å; F16-L120 HydrophobicContact CZ-CD1 4.07Å
17T97.8Very high86.8Confident0 Ų041.2 Ų41.20%021%0.211CC..EExtended strand (participates in β ladder)trans-104.5136.5171.743.80000110.4M25 G49 T77 I79 G80 I111T17-M25 HydrophobicContact CG2-CB 4.16Å; T17-M25 HydrophobicContact CG2-CG 4.46Å; T17-M25 HydrophobicContact CG2-SD 4.11Å; T17-G49 WeakPolarHBondContact O-CA 3.44Å; T17-T77 WeakPolarHBondContact CG2-OG1 3.38Å; T17-T77 WeakPolarHBondContact OG1-CB 3.38Å; T17-T77 WeakPolarHBondContact OG1-CG2 3.41Å; T17-T77 PolarHBondContact OG1-OG1 2.85Å; T17-I79 HydrophobicContact CG2-CD1 4.35Å; T17-I79 HydrophobicContact CG2-CG1 4.46Å; T17-I79 VanDerWaalsContact OG1-CG1 3.27Å; T17-I79 WeakPolarHBondContact OG1-CG1 3.41Å; T17-G80 PolarHBondContact OG1-O 2.99Å; T17-I111 CarbonylContact C-O 3.47Å; T17-I111 VanDerWaalsContact CA-O 3.24Å; T17-I111 WeakPolarHBondContact CA-O 3.36Å; T17-I111 HydrophobicContact CG2-CB 3.88Å; T17-I111 HydrophobicContact CG2-CD1 4.34Å; T17-I111 HydrophobicContact CG2-CG2 4.19Å
18S95.7Very high89.9Confident7 Ų731.5 Ų31.55%0.04917%0.169CC..EExtended strand (participates in β ladder)trans-143.2149.5-178-179.30000111.7Y50 S81 I111 G112 S116S18-Y50 WeakPolarHBondContact OG-CD2 3.36Å; S18-Y50 WeakPolarHBondContact OG-CE2 3.43Å; S18-S81 VanDerWaalsContact C-OG 3.28Å; S18-S81 VanDerWaalsContact CA-OG 3.29Å; S18-S81 WeakPolarHBondContact CA-OG 3.3Å; S18-I111 PolarHBondContact N-O 3.46Å; S18-G112 WeakPolarHBondContact O-CA 3.26Å; S18-S116 VanDerWaalsContact CB-OG 3.23Å; S18-S116 WeakPolarHBondContact CB-OG 3.47Å; S18-S116 PolarHBondContact O-OG 3Å; S18-S116 PolarHBondContact OG-OG 3.46Å
19G92.2Very high92.5Very high34 Ų3425.4 Ų25.435%0.35113%0.131SC..SBendtrans89.6-159.1-179.100000112.8S81 S116G19-S81 PolarHBondContact N-OG 2.63Å; G19-S81 PolarHBondContact O-OG 2.88Å; G19-S116 PolarHBondContact N-OG 3.24Å
20G91.6Very high94.5Very high36 Ų3619.2 Ų19.237%0.37111%0.108SC..SBendtrans-69.3135.4174.200000110.1M25G20-M25 WeakPolarHBondContact O-CE 3.3Å
21D93.7Very high95.8Very high57 Ų5712.4 Ų12.431%0.3058%0.076SC..  trans-67154.517970.5-51.8000111.7M25 G76 R296D21-M25 HydrophobicContact CB-SD 4.45Å; D21-G76 WeakPolarHBondContact OD2-CA 3.41Å; D21-R296 PolarHBondContact O-NH1 3.15Å
22A95.3Very high96.4Very high0 Ų07.4 Ų7.40%06%0.057CC..  trans-144.6139.5179.600000110G24 M25 I160 I171A22-G24 PolarHBondContact O-N 3.38Å; A22-M25 HydrophobicContact CB-CE 4.06Å; A22-M25 HydrophobicContact CB-CG 4.42Å; A22-M25 VanDerWaalsContact O-CG 3.31Å; A22-M25 WeakPolarHBondContact O-CG 3.5Å; A22-M25 PolarHBondContact O-N 3.5Å; A22-I160 HydrophobicContact CB-CG2 4.18Å; A22-I171 WeakPolarHBondContact CB-O 3.37Å
23A96.2Very high96.6Very high3 Ų37 Ų73%0.0256%0.055CC..THydrogen-bonded Turntrans-58.3125.7176.600000110.5S75 G172 S175 P300A23-S75 WeakPolarHBondContact CA-OG 3.21Å; A23-S75 WeakPolarHBondContact CB-OG 3.31Å; A23-G172 WeakPolarHBondContact O-CA 3.49Å; A23-G172 PolarHBondContact O-N 2.79Å; A23-S175 VanDerWaalsContact CB-CB 3.45Å; A23-P300 HydrophobicContact CB-CB 4.04Å; A23-P300 HydrophobicContact CB-CG 4.03Å
24G96.2Very high96.6Very high1 Ų17.9 Ų7.91%0.016%0.058CC..THydrogen-bonded Turntrans107.4-12.4-176.200000114.8A22 N26 A27 A28 A308A22-G24 PolarHBondContact O-N 3.38Å; G24-N26 VanDerWaalsContact C-N 3.27Å; G24-N26 PolarHBondContact O-N 2.91Å; G24-A27 WeakPolarHBondContact O-CA 3.43Å; G24-A27 WeakPolarHBondContact O-CB 3.32Å; G24-A27 PolarHBondContact O-N 3.19Å; G24-A28 PolarHBondContact O-N 3.03Å; G24-A28 VanDerWaalsContact O-N 3.12Å; G24-A308 VanDerWaalsContact O-CB 3.24Å; G24-A308 WeakPolarHBondContact O-CB 3.19Å
25M97.7Very high96.5Very high0 Ų07.9 Ų7.90%06%0.058CC..Hα-helixtrans-55.4-41.4173.8-74.4-176.4169.900112.4T17 G20 D21 A22 A27 A28 L29 I111 G158T17-M25 HydrophobicContact CG2-CB 4.16Å; T17-M25 HydrophobicContact CG2-CG 4.46Å; T17-M25 HydrophobicContact CG2-SD 4.11Å; G20-M25 WeakPolarHBondContact O-CE 3.3Å; D21-M25 HydrophobicContact CB-SD 4.45Å; A22-M25 HydrophobicContact CB-CE 4.06Å; A22-M25 HydrophobicContact CB-CG 4.42Å; A22-M25 VanDerWaalsContact O-CG 3.31Å; A22-M25 WeakPolarHBondContact O-CG 3.5Å; A22-M25 PolarHBondContact O-N 3.5Å; M25-A27 VanDerWaalsContact C-N 3.27Å; M25-A27 PolarHBondContact O-N 3Å; M25-A28 PolarHBondContact O-N 3.37Å; M25-L29 WeakPolarHBondContact O-CB 3.4Å; M25-L29 PolarHBondContact O-N 3.26Å; M25-I111 HydrophobicContact CB-CG2 4.24Å; M25-I111 HydrophobicContact CG-CG2 3.83Å; M25-G158 WeakPolarHBondContact CE-O 3.47Å
26N97.8Very high96.4Very high1 Ų17.9 Ų7.91%0.0056%0.058CC..Hα-helixtrans-60.9-32.6173.9-72.1-38.3000113.7G24 R30 V71 Y74 S75 G76 T77 I78G24-N26 VanDerWaalsContact C-N 3.27Å; G24-N26 PolarHBondContact O-N 2.91Å; N26-R30 WeakPolarHBondContact O-CB 3.39Å; N26-R30 PolarHBondContact O-N 3.33Å; N26-V71 HydrophobicContact CB-CB 4.2Å; N26-V71 HydrophobicContact CB-CG2 4.18Å; N26-V71 WeakPolarHBondContact CB-O 3.41Å; N26-Y74 PolarHBondContact ND2-O 3.49Å; N26-S75 PolarHBondContact ND2-O 2.51Å; N26-S75 VanDerWaalsContact ND2-O 3.14Å; N26-G76 PolarHBondContact ND2-O 3.01Å; N26-T77 WeakPolarHBondContact OD1-CA 3.24Å; N26-I78 WeakPolarHBondContact OD1-CG1 3.45Å; N26-I78 PolarHBondContact OD1-N 2.88Å
27A97.6Very high96.2Very high0 Ų010.4 Ų10.40%07%0.071CC..Hα-helixtrans-71.8-40177.300000111.3G24 M25 A31 I72 A308G24-A27 WeakPolarHBondContact O-CA 3.43Å; G24-A27 WeakPolarHBondContact O-CB 3.32Å; G24-A27 PolarHBondContact O-N 3.19Å; M25-A27 VanDerWaalsContact C-N 3.27Å; M25-A27 PolarHBondContact O-N 3Å; A27-A31 WeakPolarHBondContact O-CB 3.35Å; A27-A31 PolarHBondContact O-N 3.42Å; A27-I72 HydrophobicContact CB-CD1 4.46Å; A27-I72 HydrophobicContact CB-CG1 3.82Å; A27-A308 HydrophobicContact CB-CB 3.83Å
28A98Very high96Very high0 Ų012.9 Ų12.90%09%0.088CC..Hα-helixtrans-63.8-49.4172.100000111.1G24 M25 R30 A31 V32 I111 L156 I171 A308G24-A28 PolarHBondContact O-N 3.03Å; G24-A28 VanDerWaalsContact O-N 3.12Å; M25-A28 PolarHBondContact O-N 3.37Å; A28-R30 VanDerWaalsContact C-N 3.34Å; A28-R30 PolarHBondContact O-N 3.05Å; A28-A31 PolarHBondContact O-N 2.66Å; A28-A31 VanDerWaalsContact O-N 3.11Å; A28-V32 WeakPolarHBondContact O-CG2 3.33Å; A28-V32 PolarHBondContact O-N 3.16Å; A28-I111 HydrophobicContact CB-CD1 3.75Å; A28-I111 HydrophobicContact CB-CG1 4.33Å; A28-I111 HydrophobicContact CB-CG2 4.4Å; A28-L156 HydrophobicContact CB-CD1 4.04Å; A28-I171 HydrophobicContact CB-CD1 4.25Å; A28-A308 WeakPolarHBondContact CA-O 3.22Å; A28-A308 HydrophobicContact CB-CB 3.91Å
29L98Very high95.8Very high0 Ų015.7 Ų15.70%010%0.103CC..Hα-helixtrans-53.4-51.4176.2-176.568.5000111.1V15 M25 A31 V32 T33 L45 V68 I78 I79 I111V15-L29 HydrophobicContact CB-CD1 4.21Å; V15-L29 HydrophobicContact CG1-CD1 3.54Å; V15-L29 HydrophobicContact CG2-CD1 3.6Å; M25-L29 WeakPolarHBondContact O-CB 3.4Å; M25-L29 PolarHBondContact O-N 3.26Å; L29-A31 VanDerWaalsContact C-N 3.3Å; L29-A31 PolarHBondContact O-N 2.66Å; L29-V32 PolarHBondContact O-N 2.97Å; L29-T33 PolarHBondContact O-N 3.13Å; L29-T33 PolarHBondContact O-OG1 3.31Å; L29-T33 VanDerWaalsContact O-OG1 3.04Å; L29-L45 HydrophobicContact CD1-CD2 4.03Å; L29-V68 HydrophobicContact CG-CG1 4.41Å; L29-I78 HydrophobicContact CD2-CD1 3.89Å; L29-I78 HydrophobicContact CD2-CG1 3.59Å; L29-I79 HydrophobicContact CD1-CD1 3.81Å; L29-I79 HydrophobicContact CD2-CD1 4.19Å; L29-I79 HydrophobicContact CD2-CG1 4.12Å; L29-I79 HydrophobicContact CD2-CG2 3.87Å; L29-I111 HydrophobicContact CB-CD1 4.18Å
30R97.7Very high95.7Very high9 Ų916.6 Ų16.63%0.03411%0.112CC..Hα-helixtrans-56.3-43.6177.5176.1-179.8172.2-82.90.1112.3N26 A28 R34 V68 V71 L756N26-R30 WeakPolarHBondContact O-CB 3.39Å; N26-R30 PolarHBondContact O-N 3.33Å; A28-R30 VanDerWaalsContact C-N 3.34Å; A28-R30 PolarHBondContact O-N 3.05Å; R30-R34 WeakPolarHBondContact O-CB 3.4Å; R30-R34 WeakPolarHBondContact O-CG 3.41Å; R30-R34 PolarHBondContact O-N 3.33Å; R30-V68 HydrophobicContact CB-CB 4.11Å; R30-V68 HydrophobicContact CB-CG2 4.38Å; R30-V68 HydrophobicContact CG-CB 4.22Å; R30-V68 HydrophobicContact CG-CG2 4.08Å; R30-V71 HydrophobicContact CB-CG2 3.97Å; R30-L756 PolarHBondContact NH2-O 2.84Å; R30-L756 VanDerWaalsContact NH2-O 3.15Å
31A97.6Very high95.8Very high0 Ų015.5 Ų15.50%010%0.097CC..Hα-helixtrans-68.4-46.2-179.400000111.8A27 A28 L29 T33 R34 V35 S309 L756A27-A31 WeakPolarHBondContact O-CB 3.35Å; A27-A31 PolarHBondContact O-N 3.42Å; A28-A31 PolarHBondContact O-N 2.66Å; A28-A31 VanDerWaalsContact O-N 3.11Å; L29-A31 VanDerWaalsContact C-N 3.3Å; L29-A31 PolarHBondContact O-N 2.66Å; A31-T33 VanDerWaalsContact C-N 3.33Å; A31-T33 PolarHBondContact O-N 2.98Å; A31-R34 PolarHBondContact O-N 2.95Å; A31-V35 VanDerWaalsContact O-CB 3.29Å; A31-V35 WeakPolarHBondContact O-CB 3.31Å; A31-V35 VanDerWaalsContact O-CG2 3.25Å; A31-V35 WeakPolarHBondContact O-CG2 3.36Å; A31-V35 PolarHBondContact O-N 3.12Å; A31-S309 WeakPolarHBondContact CB-O 3.43Å; A31-L756 HydrophobicContact CB-CD2 4.26Å
32V98Very high96Very high0 Ų016.7 Ų16.70%010%0.097CC..Hα-helixtrans-56.7-48.8175.9174.80000110.5M13 V15 A28 L29 G36 V109 L156 V316M13-V32 HydrophobicContact SD-CG1 3.8Å; V15-V32 HydrophobicContact CB-CG1 3.94Å; V15-V32 HydrophobicContact CG1-CG1 4.41Å; V15-V32 HydrophobicContact CG2-CB 4.27Å; V15-V32 HydrophobicContact CG2-CG1 3.95Å; A28-V32 WeakPolarHBondContact O-CG2 3.33Å; A28-V32 PolarHBondContact O-N 3.16Å; L29-V32 PolarHBondContact O-N 2.97Å; V32-G36 WeakPolarHBondContact O-CA 3.32Å; V32-G36 PolarHBondContact O-N 2.79Å; V32-V109 HydrophobicContact CG1-CB 4.17Å; V32-V109 HydrophobicContact CG1-CG1 4.4Å; V32-V109 HydrophobicContact CG1-CG2 3.94Å; V32-V109 HydrophobicContact CG2-CG1 3.94Å; V32-L156 HydrophobicContact CG2-CD1 4.25Å; V32-V316 HydrophobicContact CB-CG2 4.37Å; V32-V316 HydrophobicContact CG1-CG2 4.04Å; V32-V316 WeakPolarHBondContact O-CG2 3.46Å
33T97.6Very high96.1Very high0 Ų016.8 Ų16.80%010%0.097CC..Hα-helixtrans-62.7-50.4-179.9-56.60000112.4L29 A31 G36 I37 V43 A63 V68L29-T33 PolarHBondContact O-N 3.13Å; L29-T33 PolarHBondContact O-OG1 3.31Å; L29-T33 VanDerWaalsContact O-OG1 3.04Å; A31-T33 VanDerWaalsContact C-N 3.33Å; A31-T33 PolarHBondContact O-N 2.98Å; T33-G36 PolarHBondContact O-N 3.39Å; T33-I37 HydrophobicContact CG2-CD1 3.76Å; T33-I37 WeakPolarHBondContact O-CB 3.26Å; T33-I37 VanDerWaalsContact O-CG1 3.26Å; T33-I37 WeakPolarHBondContact O-CG1 3.28Å; T33-I37 PolarHBondContact O-N 2.94Å; T33-V43 HydrophobicContact CG2-CG1 4.34Å; T33-A63 HydrophobicContact CG2-CB 3.61Å; T33-V68 HydrophobicContact CG2-CG1 4.04Å; T33-V68 HydrophobicContact CG2-CG2 3.89Å
34R96Very high96.2Very high17 Ų1717.1 Ų17.16%0.06410%0.098CC..Hα-helixtrans-69.3-40.2-175.8-73.2-174.5174.9-156.8-4112.6R30 A31 S38 W65 V68 S69 L756R30-R34 WeakPolarHBondContact O-CB 3.4Å; R30-R34 WeakPolarHBondContact O-CG 3.41Å; R30-R34 PolarHBondContact O-N 3.33Å; A31-R34 PolarHBondContact O-N 2.95Å; R34-S38 WeakPolarHBondContact O-CB 3.43Å; R34-S38 PolarHBondContact O-N 3.25Å; R34-S38 PolarHBondContact O-OG 3.16Å; R34-W65 HydrophobicContact CB-CE3 4.27Å; R34-W65 HydrophobicContact CB-CH2 3.66Å; R34-W65 HydrophobicContact CB-CZ2 4.25Å; R34-W65 HydrophobicContact CB-CZ3 3.69Å; R34-W65 VanDerWaalsContact CD-CZ2 3.48Å; R34-W65 HydrophobicContact CG-CD2 4.09Å; R34-W65 HydrophobicContact CG-CE3 3.98Å; R34-W65 HydrophobicContact CG-CH2 3.78Å; R34-W65 HydrophobicContact CG-CZ2 3.89Å; R34-W65 HydrophobicContact CG-CZ3 3.84Å; R34-W65 WeakPolarHBondContact O-CZ3 3.44Å; R34-V68 HydrophobicContact CG-CG2 3.92Å; R34-S69 PolarHBondContact NH2-OG 3.26Å; R34-L756 HydrophobicContact CB-CD2 3.79Å; R34-L756 VanDerWaalsContact CD-O 3.29Å; R34-L756 WeakPolarHBondContact CD-O 3.5Å; R34-L756 PolarHBondContact NH1-O 2.93Å
35V96Very high96.3Very high1 Ų117.1 Ų17.11%0.00610%0.098CC..Hα-helixtrans-71.2-39.3177.1179.80000110.3A31 S38 N39 A313 V316 L755 L756A31-V35 VanDerWaalsContact O-CB 3.29Å; A31-V35 WeakPolarHBondContact O-CB 3.31Å; A31-V35 VanDerWaalsContact O-CG2 3.25Å; A31-V35 WeakPolarHBondContact O-CG2 3.36Å; A31-V35 PolarHBondContact O-N 3.12Å; V35-S38 PolarHBondContact O-N 3.18Å; V35-N39 PolarHBondContact O-N 2.94Å; V35-N39 VanDerWaalsContact O-N 3.09Å; V35-N39 PolarHBondContact O-ND2 3.21Å; V35-A313 HydrophobicContact CG2-CB 3.9Å; V35-V316 HydrophobicContact CB-CB 4.29Å; V35-V316 HydrophobicContact CB-CG1 4.46Å; V35-V316 HydrophobicContact CB-CG2 4.19Å; V35-V316 HydrophobicContact CG1-CB 3.83Å; V35-V316 HydrophobicContact CG1-CG1 3.83Å; V35-V316 HydrophobicContact CG1-CG2 4.28Å; V35-L755 HydrophobicContact CG1-CD2 4.43Å; V35-L755 HydrophobicContact CG2-CD2 4.05Å; V35-L756 HydrophobicContact CG2-CD2 3.8Å
36G95.8Very high96.3Very high0 Ų017.1 Ų17.10%010%0.098CC..Hα-helixtrans-56.5-56.8173.400000112V32 T33 S38 N39 G40 Y41V32-G36 WeakPolarHBondContact O-CA 3.32Å; V32-G36 PolarHBondContact O-N 2.79Å; T33-G36 PolarHBondContact O-N 3.39Å; G36-S38 VanDerWaalsContact C-N 3.28Å; G36-S38 PolarHBondContact O-N 3.13Å; G36-N39 CarbonylContact O-C 3.57Å; G36-N39 PolarHBondContact O-N 3.14Å; G36-G40 PolarHBondContact O-N 2.96Å; G36-Y41 WeakPolarHBondContact O-CB 3.32Å; G36-Y41 PolarHBondContact O-N 3.39Å
37I94.3Very high96.3Very high52 Ų5219.1 Ų19.127%0.26711%0.107SC..Hα-helixtrans-57-42.6178.8-67.5168.2000111.1T33 N39 G40 V43 W65T33-I37 HydrophobicContact CG2-CD1 3.76Å; T33-I37 WeakPolarHBondContact O-CB 3.26Å; T33-I37 VanDerWaalsContact O-CG1 3.26Å; T33-I37 WeakPolarHBondContact O-CG1 3.28Å; T33-I37 PolarHBondContact O-N 2.94Å; I37-N39 PolarHBondContact O-N 3.39Å; I37-G40 PolarHBondContact O-N 3.48Å; I37-V43 HydrophobicContact CG1-CB 4.45Å; I37-V43 HydrophobicContact CG1-CG2 4.01Å; I37-W65 HydrophobicContact CG2-CE3 4.48Å
38S92.6Very high96.3Very high52 Ų5222.5 Ų22.536%0.36412%0.123SC..Hα-helixtrans-64.4-25.2179.7-57.80000113.3R34 V35 G36R34-S38 WeakPolarHBondContact O-CB 3.43Å; R34-S38 PolarHBondContact O-N 3.25Å; R34-S38 PolarHBondContact O-OG 3.16Å; V35-S38 PolarHBondContact O-N 3.18Å; G36-S38 VanDerWaalsContact C-N 3.28Å; G36-S38 PolarHBondContact O-N 3.13Å
39N91.3Very high96.2Very high66 Ų6622.5 Ų22.535%0.35312%0.123SC..THydrogen-bonded Turntrans-97.816.1176.7-72.5-77.8000112.9V35 G36 I37 Y41 M320V35-N39 PolarHBondContact O-N 2.94Å; V35-N39 VanDerWaalsContact O-N 3.09Å; V35-N39 PolarHBondContact O-ND2 3.21Å; G36-N39 CarbonylContact O-C 3.57Å; G36-N39 PolarHBondContact O-N 3.14Å; I37-N39 PolarHBondContact O-N 3.39Å; N39-Y41 HydrophobicContact CB-CD2 4.39Å; N39-M320 HydrophobicContact CB-CE 3.87Å; N39-M320 HydrophobicContact CB-SD 3.59Å; N39-M320 VanDerWaalsContact CB-SD 3.59Å; N39-M320 VanDerWaalsContact CG-SD 3.51Å; N39-M320 WeakPolarHBondContact OD1-CE 3.49Å
40G91.3Very high96.2Very high53 Ų5323.1 Ų23.155%0.54613%0.126SC..THydrogen-bonded Turntrans81.613.4173.900000115.1G36 I37G36-G40 PolarHBondContact O-N 2.96Å; I37-G40 PolarHBondContact O-N 3.48Å
41Y93.9Very high96.2Very high13 Ų1324.9 Ų24.95%0.05113%0.134CC..  trans-77.2140.5172-79.2-89.9000112R11 M13 G36 N39 V43 D107 M320R11-Y41 HydrophobicContact CB-CD1 3.71Å; R11-Y41 HydrophobicContact CB-CE1 3.46Å; R11-Y41 VanDerWaalsContact CB-CE1 3.46Å; R11-Y41 HydrophobicContact CG-CE1 4.46Å; R11-Y41 WeakPolarHBondContact O-CA 3.5Å; R11-Y41 VanDerWaalsContact O-CD1 3.32Å; R11-Y41 WeakPolarHBondContact O-CD1 3.4Å; M13-Y41 HydrophobicContact CB-CD1 3.68Å; M13-Y41 HydrophobicContact CB-CE1 4.2Å; M13-Y41 HydrophobicContact CB-CG 4.3Å; M13-Y41 HydrophobicContact CE-CD1 3.95Å; M13-Y41 HydrophobicContact CE-CD2 4.11Å; M13-Y41 HydrophobicContact CE-CE1 3.89Å; M13-Y41 HydrophobicContact CE-CE2 4.06Å; M13-Y41 HydrophobicContact CE-CG 4.05Å; G36-Y41 WeakPolarHBondContact O-CB 3.32Å; G36-Y41 PolarHBondContact O-N 3.39Å; N39-Y41 HydrophobicContact CB-CD2 4.39Å; Y41-V43 PolarHBondContact O-N 3.34Å; Y41-D107 HydrophobicContact CE1-CB 4.2Å; Y41-D107 WeakPolarHBondContact CE1-OD2 3.47Å; Y41-D107 PolarHBondContact OH-OD2 3.35Å; Y41-M320 HydrophobicContact CE2-CG 3.75Å; Y41-M320 HydrophobicContact CE2-SD 4.34Å
42R96.2Very high96.2Very high83 Ų8324.9 Ų24.931%0.31313%0.134SC..EExtended strand (participates in β ladder)trans-80106.9155.9-69-178.762.6-151.7-0.5108.2E10 R11 S12 M13 F44 E62E10-R42 WeakPolarHBondContact OE2-CD 3.39Å; R11-R42 PolarHBondContact O-N 3.5Å; S12-R42 CarbonylContact C-O 3.43Å; S12-R42 VanDerWaalsContact CA-O 3.26Å; S12-R42 WeakPolarHBondContact CA-O 3.39Å; M13-R42 PolarHBondContact N-O 3.05Å; R42-F44 HydrophobicContact CB-CE2 4.2Å; R42-E62 IonicContact CZ-OE1 2.88Å; R42-E62 IonicContact CZ-OE2 3.09Å; R42-E62 IonicContact NE-OE1 2.85Å; R42-E62 PolarHBondContact NE-OE1 3.3Å; R42-E62 IonicContact NE-OE2 3.02Å; R42-E62 IonicContact NH2-OE1 3.8Å; R42-E62 PolarHBondContact NH2-OE1 3.28Å; R42-E62 IonicContact NH2-OE2 3.69Å; R42-E62 PolarHBondContact NH2-OE2 3.13Å
43V97.6Very high96.2Very high1 Ų124.9 Ų24.91%0.00613%0.134CC..EExtended strand (participates in β ladder)trans-94.3131.1-176.1-176.60000109.6M13 V15 T33 I37 Y41 A63M13-V43 CarbonylContact O-C 3.55Å; M13-V43 WeakPolarHBondContact O-CA 3.28Å; V15-V43 HydrophobicContact CG1-CG1 4.08Å; T33-V43 HydrophobicContact CG2-CG1 4.34Å; I37-V43 HydrophobicContact CG1-CB 4.45Å; I37-V43 HydrophobicContact CG1-CG2 4.01Å; Y41-V43 PolarHBondContact O-N 3.34Å; V43-A63 HydrophobicContact CB-CB 4.25Å; V43-A63 HydrophobicContact CG1-CB 4.33Å; V43-A63 WeakPolarHBondContact O-CB 3.46Å; V43-A63 PolarHBondContact O-N 3.45Å
44F98.3Very high96.2Very high10 Ų1025.1 Ų25.14%0.04414%0.136CC..EExtended strand (participates in β ladder)trans-110.8127.7174.9-70.8-93.4000110.3M13 G14 V15 R42 F60 E61 E62 H103 I105M13-F44 PolarHBondContact O-N 3.33Å; G14-F44 CarbonylContact C-O 3.58Å; G14-F44 WeakPolarHBondContact CA-O 3.31Å; V15-F44 PolarHBondContact N-O 2.91Å; R42-F44 HydrophobicContact CB-CE2 4.2Å; F44-F60 HydrophobicContact CD1-CB 4.42Å; F44-E61 CarbonylContact C-O 3.5Å; F44-E61 VanDerWaalsContact CA-O 3.28Å; F44-E61 WeakPolarHBondContact CA-O 3.27Å; F44-E62 HydrophobicContact CD1-CB 4.13Å; F44-E62 HydrophobicContact CE1-CB 3.8Å; F44-E62 HydrophobicContact CE1-CG 4.33Å; F44-E62 HydrophobicContact CZ-CB 4.31Å; F44-E62 HydrophobicContact CZ-CG 4.36Å; F44-H103 AromaticContact CE1-CD2 3.94Å; F44-I105 HydrophobicContact CB-CD1 3.8Å; F44-I105 HydrophobicContact CD2-CD1 4Å; F44-I105 HydrophobicContact CD2-CG1 3.99Å; F44-I105 HydrophobicContact CG-CD1 3.94Å; F44-I105 HydrophobicContact CG-CG1 4.44Å
45L98.4Very high96.2Very high2 Ų227.2 Ų27.21%0.0115%0.148CC..EExtended strand (participates in β ladder)trans-84.5118.9167.7-50.1-176.2000107.9V15 L29 E61 A63 I79V15-L45 HydrophobicContact CG1-CD2 3.68Å; L29-L45 HydrophobicContact CD1-CD2 4.03Å; L45-E61 HydrophobicContact CB-CB 4.31Å; L45-E61 PolarHBondContact N-O 3.22Å; L45-E61 PolarHBondContact O-N 2.98Å; L45-A63 HydrophobicContact CD1-CB 4.22Å; L45-A63 HydrophobicContact CD2-CB 3.85Å; L45-A63 HydrophobicContact CG-CB 3.74Å; L45-I79 HydrophobicContact CB-CG2 3.96Å; L45-I79 HydrophobicContact CD1-CG2 4.05Å; L45-I79 HydrophobicContact CG-CG2 4.46Å
46I98.4Very high96.2Very high0 Ų027.4 Ų27.40%015%0.15CC..EExtended strand (participates in β ladder)trans-97.9106.9176.4-47.1173.7000108V15 F16 M53 Y59 F60 L100 L108V15-I46 PolarHBondContact O-N 3.41Å; F16-I46 HydrophobicContact CB-CB 3.8Å; F16-I46 HydrophobicContact CB-CD1 4.41Å; F16-I46 HydrophobicContact CB-CG1 4.45Å; I46-M53 HydrophobicContact CD1-CE 3.94Å; I46-M53 HydrophobicContact CG2-CB 4.01Å; I46-Y59 WeakPolarHBondContact CA-O 3.12Å; I46-F60 HydrophobicContact CD1-CD1 4.37Å; I46-F60 HydrophobicContact CD1-CE1 3.68Å; I46-F60 HydrophobicContact CD1-CZ 4.15Å; I46-F60 HydrophobicContact CG1-CD1 3.92Å; I46-F60 HydrophobicContact CG1-CE1 3.7Å; I46-F60 HydrophobicContact CG1-CZ 4.27Å; I46-F60 HydrophobicContact CG2-CE1 4.32Å; I46-F60 HydrophobicContact CG2-CE2 4.2Å; I46-F60 HydrophobicContact CG2-CZ 4.05Å; I46-L100 HydrophobicContact CD1-CD2 4.04Å; I46-L108 HydrophobicContact CD1-CD1 3.82Å
47H98Very high96.1Very high43 Ų4329.7 Ų29.720%0.19917%0.174CC..THydrogen-bonded Turntrans-71.6151.8-177.3-70.7-90.9000111.8G49 G52 Y59 E61 I79H47-G49 PolarHBondContact O-N 3.47Å; H47-G49 VanDerWaalsContact O-N 3.08Å; H47-G52 WeakPolarHBondContact O-CA 3.16Å; H47-G52 PolarHBondContact O-N 3.19Å; H47-Y59 HydrophobicContact CB-CD1 3.89Å; H47-Y59 PolarHBondContact CD2-O 2.87Å; H47-Y59 PolarHBondContact N-O 2.89Å; H47-E61 IonicContact CE1-OE2 2.97Å; H47-E61 PolarHBondContact CE1-OE2 3.24Å; H47-E61 IonicContact NE2-OE2 3.11Å; H47-E61 PolarHBondContact NE2-OE2 3.38Å; H47-I79 CarbonylContact C-O 3.53Å; H47-I79 WeakPolarHBondContact CA-O 3.45Å
48E97.2Very high96.1Very high70 Ų7035 Ų3533%0.32720%0.203SC..THydrogen-bonded Turntrans55.925.2178.3-57.9-53.4142.800115.2Y50 Q51 Y59 I79 G80 S81 A82E48-Y50 PolarHBondContact O-N 2.85Å; E48-Q51 HydrophobicContact CB-CB 4.4Å; E48-Q51 WeakPolarHBondContact O-CB 3.34Å; E48-Q51 PolarHBondContact O-N 3.33Å; E48-Y59 HydrophobicContact CB-CD1 4.29Å; E48-Y59 HydrophobicContact CB-CE1 4.08Å; E48-Y59 HydrophobicContact CG-CD1 4.25Å; E48-Y59 HydrophobicContact CG-CE1 3.77Å; E48-I79 PolarHBondContact N-O 2.78Å; E48-G80 WeakPolarHBondContact OE1-CA 3.44Å; E48-S81 PolarHBondContact OE2-N 2.79Å; E48-A82 HydrophobicContact CB-CB 3.95Å; E48-A82 PolarHBondContact O-N 3.16Å
49G96.9Very high96.3Very high0 Ų036.7 Ų36.70%020%0.202CC..THydrogen-bonded Turntrans60.4-132.8175.100000113.3T17 H47 Q51 G52 M53T17-G49 WeakPolarHBondContact O-CA 3.44Å; H47-G49 PolarHBondContact O-N 3.47Å; H47-G49 VanDerWaalsContact O-N 3.08Å; G49-Q51 PolarHBondContact O-N 2.93Å; G49-G52 PolarHBondContact O-N 3.16Å; G49-M53 PolarHBondContact O-N 3.37Å; G49-M53 VanDerWaalsContact O-N 3.1Å
50Y97.7Very high96.6Very high14 Ų1434.2 Ų34.26%0.05519%0.188CC..Hα-helixtrans-63.1-25.6178.4-72.7-60.2000113.1F16 S18 E48 M53 V54 F87 S116 L120F16-Y50 HydrophobicContact CE2-CD1 4.05Å; F16-Y50 HydrophobicContact CE2-CD2 4.32Å; F16-Y50 AromaticContact CE2-CE1 3.67Å; F16-Y50 HydrophobicContact CE2-CE1 3.67Å; F16-Y50 AromaticContact CE2-CE2 3.96Å; F16-Y50 HydrophobicContact CE2-CE2 3.96Å; F16-Y50 HydrophobicContact CE2-CG 4.35Å; F16-Y50 AromaticContact CE2-CZ 3.62Å; F16-Y50 HydrophobicContact CZ-CD1 4.39Å; F16-Y50 AromaticContact CZ-CE1 3.65Å; F16-Y50 HydrophobicContact CZ-CE1 3.65Å; F16-Y50 HydrophobicContact CZ-CE2 4.44Å; F16-Y50 AromaticContact CZ-CZ 3.67Å; S18-Y50 WeakPolarHBondContact OG-CD2 3.36Å; S18-Y50 WeakPolarHBondContact OG-CE2 3.43Å; E48-Y50 PolarHBondContact O-N 2.85Å; Y50-M53 HydrophobicContact CD1-CE 4.16Å; Y50-M53 HydrophobicContact CD1-SD 4.06Å; Y50-M53 HydrophobicContact CE1-CE 4.25Å; Y50-M53 HydrophobicContact CE1-SD 4.34Å; Y50-M53 PolarHBondContact O-N 3.27Å; Y50-V54 VanDerWaalsContact O-CG2 3.27Å; Y50-V54 WeakPolarHBondContact O-CG2 3.25Å; Y50-V54 PolarHBondContact O-N 3.33Å; Y50-F87 AromaticContact CD1-CD1 3.9Å; Y50-F87 HydrophobicContact CD1-CD1 3.9Å; Y50-F87 AromaticContact CD1-CD2 3.78Å; Y50-F87 HydrophobicContact CD1-CD2 3.78Å; Y50-F87 AromaticContact CD1-CE1 3.66Å; Y50-F87 HydrophobicContact CD1-CE1 3.66Å; Y50-F87 AromaticContact CD1-CE2 3.52Å; Y50-F87 HydrophobicContact CD1-CE2 3.52Å; Y50-F87 AromaticContact CD1-CG 3.95Å; Y50-F87 HydrophobicContact CD1-CG 3.95Å; Y50-F87 AromaticContact CD1-CZ 3.46Å; Y50-F87 HydrophobicContact CD1-CZ 3.46Å; Y50-F87 VanDerWaalsContact CD1-CZ 3.46Å; Y50-F87 HydrophobicContact CD2-CD1 4.36Å; Y50-F87 HydrophobicContact CE1-CD1 4.21Å; Y50-F87 AromaticContact CE1-CE1 3.56Å; Y50-F87 HydrophobicContact CE1-CE1 3.56Å; Y50-F87 AromaticContact CE1-CE2 3.93Å; Y50-F87 HydrophobicContact CE1-CE2 3.93Å; Y50-F87 AromaticContact CE1-CZ 3.39Å; Y50-F87 HydrophobicContact CE1-CZ 3.39Å; Y50-F87 HydrophobicContact CE2-CE1 4.47Å; Y50-F87 AromaticContact CG-CD1 3.99Å; Y50-F87 HydrophobicContact CG-CD1 3.99Å; Y50-F87 HydrophobicContact CG-CD2 4.2Å; Y50-F87 HydrophobicContact CG-CE1 4.18Å; Y50-F87 HydrophobicContact CG-CE2 4.37Å; Y50-F87 AromaticContact CG-CG 4Å; Y50-F87 HydrophobicContact CG-CG 4Å; Y50-F87 HydrophobicContact CG-CZ 4.36Å; Y50-F87 AromaticContact CZ-CE1 3.99Å; Y50-S116 PolarHBondContact OH-O 3.07Å; Y50-L120 WeakPolarHBondContact OH-CA 3.26Å; Y50-L120 PolarHBondContact OH-N 3.15Å
51Q97.2Very high96.9Very high45 Ų4535 Ų3521%0.2118%0.178CC..Hα-helixtrans-66.4-52.4179.5-173.657.252.100110.4E48 G49 M53 V54 D55 A82 C84E48-Q51 HydrophobicContact CB-CB 4.4Å; E48-Q51 WeakPolarHBondContact O-CB 3.34Å; E48-Q51 PolarHBondContact O-N 3.33Å; G49-Q51 PolarHBondContact O-N 2.93Å; Q51-M53 VanDerWaalsContact C-N 3.25Å; Q51-M53 PolarHBondContact O-N 3.05Å; Q51-V54 PolarHBondContact O-N 3.12Å; Q51-V54 VanDerWaalsContact O-N 3.1Å; Q51-D55 VanDerWaalsContact NE2-CG 3.26Å; Q51-D55 PolarHBondContact NE2-OD1 2.82Å; Q51-D55 VanDerWaalsContact NE2-OD1 3.11Å; Q51-D55 PolarHBondContact NE2-OD2 2.93Å; Q51-D55 PolarHBondContact O-N 2.94Å; Q51-A82 HydrophobicContact CB-CB 3.8Å; Q51-A82 HydrophobicContact CG-CB 4.35Å; Q51-C84 HydrophobicContact CB-CB 4.13Å; Q51-C84 PolarHBondContact OE1-SG 3.28Å
52G97.5Very high97.1Very high0 Ų039 Ų390%020%0.197CC..Hα-helixtrans-65.7-29.7175.700000113H47 G49 V54 D55 G56 Y59H47-G52 WeakPolarHBondContact O-CA 3.16Å; H47-G52 PolarHBondContact O-N 3.19Å; G49-G52 PolarHBondContact O-N 3.16Å; G52-V54 VanDerWaalsContact C-N 3.31Å; G52-V54 PolarHBondContact O-N 3.11Å; G52-D55 PolarHBondContact O-N 3.08Å; G52-G56 PolarHBondContact O-N 3.02Å; G52-Y59 VanDerWaalsContact CA-CG 3.48Å
53M97.7Very high97.1Very high0 Ų035.5 Ų35.50%019%0.186CC..Hα-helixtrans-60.7-39.7171.7-163.5-175.3-7000112.4F16 I46 G49 Y50 Q51 F60 F87 A96 N99 L100 L108 L123F16-M53 HydrophobicContact CD1-CE 3.77Å; F16-M53 HydrophobicContact CD2-CE 4.22Å; F16-M53 HydrophobicContact CE1-CE 3.7Å; F16-M53 HydrophobicContact CE2-CE 4.13Å; F16-M53 HydrophobicContact CG-CE 4.04Å; F16-M53 HydrophobicContact CZ-CE 3.87Å; I46-M53 HydrophobicContact CD1-CE 3.94Å; I46-M53 HydrophobicContact CG2-CB 4.01Å; G49-M53 PolarHBondContact O-N 3.37Å; G49-M53 VanDerWaalsContact O-N 3.1Å; Y50-M53 HydrophobicContact CD1-CE 4.16Å; Y50-M53 HydrophobicContact CD1-SD 4.06Å; Y50-M53 HydrophobicContact CE1-CE 4.25Å; Y50-M53 HydrophobicContact CE1-SD 4.34Å; Y50-M53 PolarHBondContact O-N 3.27Å; Q51-M53 VanDerWaalsContact C-N 3.25Å; Q51-M53 PolarHBondContact O-N 3.05Å; M53-F60 HydrophobicContact CG-CZ 4.23Å; M53-F87 HydrophobicContact SD-CE2 4.36Å; M53-A96 HydrophobicContact CB-CB 4.48Å; M53-A96 HydrophobicContact CG-CB 3.85Å; M53-A96 WeakPolarHBondContact O-CA 3.29Å; M53-A96 HydrophobicContact SD-CB 4.04Å; M53-N99 PolarHBondContact O-ND2 3.3Å; M53-L100 HydrophobicContact CG-CD1 4.44Å; M53-L100 HydrophobicContact CG-CG 4.34Å; M53-L100 HydrophobicContact SD-CD1 3.97Å; M53-L100 HydrophobicContact SD-CG 4.46Å; M53-L108 HydrophobicContact CE-CD1 4.28Å; M53-L108 HydrophobicContact CE-CD2 4.02Å; M53-L123 HydrophobicContact SD-CD2 4.32Å
54V97.5Very high96.8Very high5 Ų538.1 Ų38.13%0.0320%0.204CC..Hα-helixtrans-76-37.5176173.20000111.7Y50 Q51 G52 A86 F87 K95 A96 N99Y50-V54 VanDerWaalsContact O-CG2 3.27Å; Y50-V54 WeakPolarHBondContact O-CG2 3.25Å; Y50-V54 PolarHBondContact O-N 3.33Å; Q51-V54 PolarHBondContact O-N 3.12Å; Q51-V54 VanDerWaalsContact O-N 3.1Å; G52-V54 VanDerWaalsContact C-N 3.31Å; G52-V54 PolarHBondContact O-N 3.11Å; V54-A86 HydrophobicContact CG1-CB 4.06Å; V54-F87 HydrophobicContact CG2-CB 4.28Å; V54-F87 HydrophobicContact CG2-CD2 3.82Å; V54-K95 HydrophobicContact CG1-CB 4.44Å; V54-K95 HydrophobicContact CG1-CD 4.04Å; V54-K95 WeakPolarHBondContact O-CD 3.36Å; V54-K95 WeakPolarHBondContact O-CE 3.39Å; V54-K95 WeakPolarHBondContact O-CG 3.23Å; V54-K95 PolarHBondContact O-NZ 2.87Å; V54-K95 VanDerWaalsContact O-NZ 3.15Å; V54-A96 HydrophobicContact CG2-CB 4.07Å; V54-N99 PolarHBondContact O-ND2 2.8Å
55D96.9Very high96.3Very high61 Ų6140.2 Ų40.233%0.32621%0.212SC..Hα-helixtrans-73.3-36.9-176.2-69.1-22.4000112.1Q51 G52 Y59Q51-D55 VanDerWaalsContact NE2-CG 3.26Å; Q51-D55 PolarHBondContact NE2-OD1 2.82Å; Q51-D55 VanDerWaalsContact NE2-OD1 3.11Å; Q51-D55 PolarHBondContact NE2-OD2 2.93Å; Q51-D55 PolarHBondContact O-N 2.94Å; G52-D55 PolarHBondContact O-N 3.08Å; D55-Y59 HydrophobicContact CB-CD2 3.73Å; D55-Y59 HydrophobicContact CB-CE2 3.71Å
56G94.7Very high95.8Very high5 Ų544.4 Ų44.45%0.05223%0.234CC..  trans74-166.3177.500000113.2G52 D58 Y59 N99G52-G56 PolarHBondContact O-N 3.02Å; G56-D58 PolarHBondContact O-N 3.02Å; G56-Y59 WeakPolarHBondContact O-CD2 3.44Å; G56-N99 VanDerWaalsContact CA-ND2 3.32Å; G56-N99 WeakPolarHBondContact CA-ND2 3.45Å; G56-N99 PolarHBondContact N-ND2 2.9Å
57G94.2Very high95.5Very high49 Ų4945.9 Ų45.951%0.50525%0.245SC..G310 helixtrans62.8-129.8177.300000113Y59 F60G57-Y59 PolarHBondContact O-N 3Å; G57-F60 PolarHBondContact O-N 2.92Å
58D94.2Very high95.3Very high163 Ų16343.9 Ų43.987%0.87224%0.235SC*.G310 helixtrans-62-12.8-174-60.7-25.1000114.4G56 F60G56-D58 PolarHBondContact O-N 3.02Å; D58-F60 PolarHBondContact O-N 3.01Å
59Y97.6Very high94.9Very high88 Ų8842.5 Ų42.535%0.34523%0.233SC..G310 helixtrans-68.6-13.8171-72.8-80000113.2I46 H47 E48 G52 D55 G56 G57I46-Y59 WeakPolarHBondContact CA-O 3.12Å; H47-Y59 HydrophobicContact CB-CD1 3.89Å; H47-Y59 PolarHBondContact CD2-O 2.87Å; H47-Y59 PolarHBondContact N-O 2.89Å; E48-Y59 HydrophobicContact CB-CD1 4.29Å; E48-Y59 HydrophobicContact CB-CE1 4.08Å; E48-Y59 HydrophobicContact CG-CD1 4.25Å; E48-Y59 HydrophobicContact CG-CE1 3.77Å; G52-Y59 VanDerWaalsContact CA-CG 3.48Å; D55-Y59 HydrophobicContact CB-CD2 3.73Å; D55-Y59 HydrophobicContact CB-CE2 3.71Å; G56-Y59 WeakPolarHBondContact O-CD2 3.44Å; G57-Y59 PolarHBondContact O-N 3Å
60F98Very high94.4Very high14 Ų1444.2 Ų44.26%0.06124%0.243CC..EExtended strand (participates in β ladder)trans-101.7100.4173.1-73.5-106.1000109.6F44 I46 M53 G57 D58 N99 L100 H103 I105F44-F60 HydrophobicContact CD1-CB 4.42Å; I46-F60 HydrophobicContact CD1-CD1 4.37Å; I46-F60 HydrophobicContact CD1-CE1 3.68Å; I46-F60 HydrophobicContact CD1-CZ 4.15Å; I46-F60 HydrophobicContact CG1-CD1 3.92Å; I46-F60 HydrophobicContact CG1-CE1 3.7Å; I46-F60 HydrophobicContact CG1-CZ 4.27Å; I46-F60 HydrophobicContact CG2-CE1 4.32Å; I46-F60 HydrophobicContact CG2-CE2 4.2Å; I46-F60 HydrophobicContact CG2-CZ 4.05Å; M53-F60 HydrophobicContact CG-CZ 4.23Å; G57-F60 PolarHBondContact O-N 2.92Å; D58-F60 PolarHBondContact O-N 3.01Å; F60-N99 HydrophobicContact CE2-CB 4.04Å; F60-N99 HydrophobicContact CZ-CB 4.07Å; F60-L100 HydrophobicContact CE1-CD2 4.03Å; F60-L100 HydrophobicContact CZ-CD2 4.36Å; F60-H103 WeakPolarHBondContact CB-NE2 3.34Å; F60-H103 HydrophobicContact CD1-CB 4.42Å; F60-H103 AromaticContact CD1-CG 3.92Å; F60-H103 AromaticContact CD1-ND1 3.85Å; F60-H103 AromaticContact CD2-CE1 3.94Å; F60-H103 AromaticContact CG-CE1 3.69Å; F60-H103 AromaticContact CG-ND1 3.86Å; F60-H103 AromaticContact CG-NE2 3.9Å; F60-I105 HydrophobicContact CD1-CD1 3.72Å; F60-I105 HydrophobicContact CE1-CD1 3.7Å
61E97.3Very high94.2Very high70 Ų7044 Ų4433%0.32724%0.243SC..EExtended strand (participates in β ladder)trans-96.1122175.8179.7-164.1152.700110F44 L45 H47 A63 S67F44-E61 CarbonylContact C-O 3.5Å; F44-E61 VanDerWaalsContact CA-O 3.28Å; F44-E61 WeakPolarHBondContact CA-O 3.27Å; L45-E61 HydrophobicContact CB-CB 4.31Å; L45-E61 PolarHBondContact N-O 3.22Å; L45-E61 PolarHBondContact O-N 2.98Å; H47-E61 IonicContact CE1-OE2 2.97Å; H47-E61 PolarHBondContact CE1-OE2 3.24Å; H47-E61 IonicContact NE2-OE2 3.11Å; H47-E61 PolarHBondContact NE2-OE2 3.38Å; E61-A63 PolarHBondContact O-N 3.16Å; E61-S67 PolarHBondContact OE1-OG 2.96Å
62E97.1Very high94.1Very high95 Ų9542 Ų4244%0.44423%0.233SC..EExtended strand (participates in β ladder)trans-68.6114.9168.2-173.4165.4-173.700110R42 F44R42-E62 IonicContact CZ-OE1 2.88Å; R42-E62 IonicContact CZ-OE2 3.09Å; R42-E62 IonicContact NE-OE1 2.85Å; R42-E62 PolarHBondContact NE-OE1 3.3Å; R42-E62 IonicContact NE-OE2 3.02Å; R42-E62 IonicContact NH2-OE1 3.8Å; R42-E62 PolarHBondContact NH2-OE1 3.28Å; R42-E62 IonicContact NH2-OE2 3.69Å; R42-E62 PolarHBondContact NH2-OE2 3.13Å; F44-E62 HydrophobicContact CD1-CB 4.13Å; F44-E62 HydrophobicContact CE1-CB 3.8Å; F44-E62 HydrophobicContact CE1-CG 4.33Å; F44-E62 HydrophobicContact CZ-CB 4.31Å; F44-E62 HydrophobicContact CZ-CG 4.36Å
63A96.3Very high93.9Very high11 Ų1142.8 Ų42.89%0.09124%0.237CC..  trans-75.9134.7-172.300000111.3T33 V43 L45 E61T33-A63 HydrophobicContact CG2-CB 3.61Å; V43-A63 HydrophobicContact CB-CB 4.25Å; V43-A63 HydrophobicContact CG1-CB 4.33Å; V43-A63 WeakPolarHBondContact O-CB 3.46Å; V43-A63 PolarHBondContact O-N 3.45Å; L45-A63 HydrophobicContact CD1-CB 4.22Å; L45-A63 HydrophobicContact CD2-CB 3.85Å; L45-A63 HydrophobicContact CG-CB 3.74Å; E61-A63 PolarHBondContact O-N 3.16Å
64S92.3Very high93.8Very high55 Ų5547.5 Ų47.539%0.38526%0.256SS..  trans-97.8169.6163.673.60000110.9N66 S67S64-N66 PolarHBondContact O-N 3.29Å; S64-N66 VanDerWaalsContact O-N 3.15Å; S64-N66 PolarHBondContact OG-N 2.82Å; S64-S67 PolarHBondContact N-OG 2.87Å; S64-S67 WeakPolarHBondContact O-CB 3.37Å; S64-S67 PolarHBondContact O-N 2.87Å; S64-S67 VanDerWaalsContact O-N 3.13Å; S64-S67 PolarHBondContact OG-N 3Å; S64-S67 VanDerWaalsContact OG-N 3.13Å; S64-S67 PolarHBondContact OG-OG 3.06Å; S64-S67 VanDerWaalsContact OG-OG 3.08Å
65W88Confident93.6Very high54 Ų5448.7 Ų48.721%0.20526%0.264CS..THydrogen-bonded Turntrans-54.2-33.5169.2-167.7-91000112.9R34 I37 S69 L755 L756 A758R34-W65 HydrophobicContact CB-CE3 4.27Å; R34-W65 HydrophobicContact CB-CH2 3.66Å; R34-W65 HydrophobicContact CB-CZ2 4.25Å; R34-W65 HydrophobicContact CB-CZ3 3.69Å; R34-W65 VanDerWaalsContact CD-CZ2 3.48Å; R34-W65 HydrophobicContact CG-CD2 4.09Å; R34-W65 HydrophobicContact CG-CE3 3.98Å; R34-W65 HydrophobicContact CG-CH2 3.78Å; R34-W65 HydrophobicContact CG-CZ2 3.89Å; R34-W65 HydrophobicContact CG-CZ3 3.84Å; R34-W65 WeakPolarHBondContact O-CZ3 3.44Å; I37-W65 HydrophobicContact CG2-CE3 4.48Å; W65-S69 PolarHBondContact O-OG 3.19Å; W65-L755 VanDerWaalsContact CH2-O 3.27Å; W65-L755 WeakPolarHBondContact CH2-O 3.38Å; W65-L756 VanDerWaalsContact CZ2-O 3.28Å; W65-L756 WeakPolarHBondContact CZ2-O 3.4Å; W65-A758 HydrophobicContact CD2-CB 4.33Å; W65-A758 HydrophobicContact CH2-CB 3.95Å; W65-A758 HydrophobicContact CZ2-CB 3.52Å; W65-A758 HydrophobicContact CZ3-CB 4.49Å
66N87.9Confident93.4Very high90 Ų9046.3 Ų46.348%0.48125%0.254SS..THydrogen-bonded Turntrans-79.2-26.9-177.5-70.9-15.6000112.5S64 V68 S69S64-N66 PolarHBondContact O-N 3.29Å; S64-N66 VanDerWaalsContact O-N 3.15Å; S64-N66 PolarHBondContact OG-N 2.82Å; N66-V68 PolarHBondContact O-N 2.83Å; N66-V68 VanDerWaalsContact O-N 3.09Å; N66-S69 WeakPolarHBondContact O-CB 3.43Å; N66-S69 PolarHBondContact O-N 3.28Å
67S91.2Very high93.5Very high32 Ų3247.3 Ų47.322%0.22426%0.259CS..THydrogen-bonded Turntrans-57.3-27.3179.5-58.40000112.9E61 S64E61-S67 PolarHBondContact OE1-OG 2.96Å; S64-S67 PolarHBondContact N-OG 2.87Å; S64-S67 WeakPolarHBondContact O-CB 3.37Å; S64-S67 PolarHBondContact O-N 2.87Å; S64-S67 VanDerWaalsContact O-N 3.13Å; S64-S67 PolarHBondContact OG-N 3Å; S64-S67 VanDerWaalsContact OG-N 3.13Å; S64-S67 PolarHBondContact OG-OG 3.06Å; S64-S67 VanDerWaalsContact OG-OG 3.08Å
68V93.3Very high93.6Very high0 Ų048.5 Ų48.50%025%0.253CS..THydrogen-bonded Turntrans-114.323.8178.4-62.30000113.4L29 R30 T33 R34 N66 V71L29-V68 HydrophobicContact CG-CG1 4.41Å; R30-V68 HydrophobicContact CB-CB 4.11Å; R30-V68 HydrophobicContact CB-CG2 4.38Å; R30-V68 HydrophobicContact CG-CB 4.22Å; R30-V68 HydrophobicContact CG-CG2 4.08Å; T33-V68 HydrophobicContact CG2-CG1 4.04Å; T33-V68 HydrophobicContact CG2-CG2 3.89Å; R34-V68 HydrophobicContact CG-CG2 3.92Å; N66-V68 PolarHBondContact O-N 2.83Å; N66-V68 VanDerWaalsContact O-N 3.09Å; V68-V71 HydrophobicContact CB-CG2 4.32Å; V68-V71 WeakPolarHBondContact O-CG2 3.43Å
69S88.9Confident93.7Very high41 Ų4140.8 Ų40.829%0.28721%0.212SC..THydrogen-bonded Turntrans-79.8142.8176.7-710000111.9R34 W65 N66 V71R34-S69 PolarHBondContact NH2-OG 3.26Å; W65-S69 PolarHBondContact O-OG 3.19Å; N66-S69 WeakPolarHBondContact O-CB 3.43Å; N66-S69 PolarHBondContact O-N 3.28Å; S69-V71 WeakPolarHBondContact O-CG1 3.38Å; S69-V71 PolarHBondContact O-N 2.93Å; S69-V71 VanDerWaalsContact O-N 3.12Å
70D87Confident93.6Very high37 Ų3737.2 Ų37.220%0.19820%0.202CC..THydrogen-bonded Turntrans54.823.9-179.1-67.7-11.5000116.2Q73 Y74 R564 R625D70-Q73 PolarHBondContact O-NE2 2.54Å; D70-Q73 PolarHBondContact O-OE1 2.83Å; D70-Y74 WeakPolarHBondContact O-CD2 3.36Å; D70-Y74 WeakPolarHBondContact O-CE2 3.28Å; D70-R564 IonicContact OD2-CZ 2.88Å; D70-R564 IonicContact OD2-NE 3.65Å; D70-R564 PolarHBondContact OD2-NE 3.22Å; D70-R564 IonicContact OD2-NH2 3.66Å; D70-R564 PolarHBondContact OD2-NH2 3.23Å; D70-R625 IonicContact OD1-CZ 3.71Å; D70-R625 IonicContact OD1-NE 3.11Å; D70-R625 PolarHBondContact OD1-NE 3.44Å; D70-R625 IonicContact OD1-NH2 2.79Å; D70-R625 PolarHBondContact OD1-NH2 3.13Å; D70-R625 IonicContact OD2-NE 2.63Å
71V93.7Very high93.5Very high10 Ų1038.1 Ų38.16%0.06121%0.21CC..  trans-92.2-16.2179.7-55.60000114.2N26 R30 V68 S69 Q73 Y74 I78N26-V71 HydrophobicContact CB-CB 4.2Å; N26-V71 HydrophobicContact CB-CG2 4.18Å; N26-V71 WeakPolarHBondContact CB-O 3.41Å; R30-V71 HydrophobicContact CB-CG2 3.97Å; V68-V71 HydrophobicContact CB-CG2 4.32Å; V68-V71 WeakPolarHBondContact O-CG2 3.43Å; S69-V71 WeakPolarHBondContact O-CG1 3.38Å; S69-V71 PolarHBondContact O-N 2.93Å; S69-V71 VanDerWaalsContact O-N 3.12Å; V71-Q73 PolarHBondContact O-N 3.35Å; V71-Q73 VanDerWaalsContact O-N 3.15Å; V71-Y74 PolarHBondContact O-N 3.09Å; V71-Y74 VanDerWaalsContact O-N 3.07Å; V71-I78 HydrophobicContact CB-CG2 4.3Å; V71-I78 HydrophobicContact CG1-CD1 3.97Å; V71-I78 HydrophobicContact CG1-CG1 4.39Å; V71-I78 HydrophobicContact CG1-CG2 3.97Å
72I95.3Very high93.2Very high2 Ų236.2 Ų36.21%0.0121%0.206CC..THydrogen-bonded Turntrans-62.6-27.7-167.8-161.5168.4000114A27 R305 A590A27-I72 HydrophobicContact CB-CD1 4.46Å; A27-I72 HydrophobicContact CB-CG1 3.82Å; I72-R305 HydrophobicContact CG1-CB 4.4Å; I72-R305 HydrophobicContact CG1-CG 4.31Å; I72-A590 VanDerWaalsContact CD1-O 3.31Å; I72-A590 WeakPolarHBondContact CD1-O 3.42Å
73Q94.2Very high92.8Very high17 Ų1743.3 Ų43.38%0.07923%0.229CC..THydrogen-bonded Turntrans-90.4-2.7-18071.1-80.2-6.400114.6D70 V71 P300 D557D70-Q73 PolarHBondContact O-NE2 2.54Å; D70-Q73 PolarHBondContact O-OE1 2.83Å; V71-Q73 PolarHBondContact O-N 3.35Å; V71-Q73 VanDerWaalsContact O-N 3.15Å; Q73-P300 VanDerWaalsContact O-CD 3.28Å; Q73-P300 WeakPolarHBondContact O-CD 3.4Å; Q73-D557 HydrophobicContact CB-CB 4.44Å; Q73-D557 VanDerWaalsContact CB-CG 3.46Å; Q73-D557 WeakPolarHBondContact CB-OD1 3.42Å; Q73-D557 WeakPolarHBondContact CB-OD2 3.4Å
74Y94.3Very high92.6Very high99 Ų9943.8 Ų43.839%0.38823%0.231SC..  trans-95.6136.8180-61.3-55.7000111.3N26 D70 V71 R564N26-Y74 PolarHBondContact ND2-O 3.49Å; D70-Y74 WeakPolarHBondContact O-CD2 3.36Å; D70-Y74 WeakPolarHBondContact O-CE2 3.28Å; V71-Y74 PolarHBondContact O-N 3.09Å; V71-Y74 VanDerWaalsContact O-N 3.07Å; Y74-R564 PolarHBondContact OH-NH1 2.75Å; Y74-R564 PolarHBondContact OH-NH2 2.83Å
75S92.9Very high92.6Very high30 Ų3050 Ų5021%0.2125%0.251CS..  trans-70.5178.2167.1-145.60000111.9A23 N26 R296 G298A23-S75 WeakPolarHBondContact CA-OG 3.21Å; A23-S75 WeakPolarHBondContact CB-OG 3.31Å; N26-S75 PolarHBondContact ND2-O 2.51Å; N26-S75 VanDerWaalsContact ND2-O 3.14Å; S75-R296 PolarHBondContact OG-O 2.64Å; S75-R296 VanDerWaalsContact OG-O 3.04Å; S75-G298 WeakPolarHBondContact CB-O 3.31Å; S75-G298 PolarHBondContact OG-O 2.75Å
76G94.1Very high92.8Very high10 Ų1049.2 Ų49.210%0.10326%0.256CS..SBendtrans67.5-149.1179.700000111.1D21 N26D21-G76 WeakPolarHBondContact OD2-CA 3.41Å; N26-G76 PolarHBondContact ND2-O 3.01Å
77T96.2Very high93.1Very high26 Ų2645.6 Ų45.616%0.1624%0.236CC..  trans-138130.5177.7172.60000110T17 N26 I79 G80T17-T77 WeakPolarHBondContact CG2-OG1 3.38Å; T17-T77 WeakPolarHBondContact OG1-CB 3.38Å; T17-T77 WeakPolarHBondContact OG1-CG2 3.41Å; T17-T77 PolarHBondContact OG1-OG1 2.85Å; N26-T77 WeakPolarHBondContact OD1-CA 3.24Å; T77-I79 PolarHBondContact O-N 2.78Å; T77-I79 VanDerWaalsContact OG1-CG1 3.24Å; T77-I79 WeakPolarHBondContact OG1-CG1 3.45Å; T77-I79 PolarHBondContact OG1-N 2.83Å; T77-G80 VanDerWaalsContact CG2-C 3.5Å; T77-G80 VanDerWaalsContact CG2-O 3.29Å; T77-G80 WeakPolarHBondContact CG2-O 3.42Å; T77-G80 PolarHBondContact O-N 2.74Å
78I96.3Very high93.2Very high74 Ų7451.4 Ų51.438%0.37926%0.261SS..THydrogen-bonded Turntrans-70.2-14.5177.855.4141.4000113.3N26 L29 V71N26-I78 WeakPolarHBondContact OD1-CG1 3.45Å; N26-I78 PolarHBondContact OD1-N 2.88Å; L29-I78 HydrophobicContact CD2-CD1 3.89Å; L29-I78 HydrophobicContact CD2-CG1 3.59Å; V71-I78 HydrophobicContact CB-CG2 4.3Å; V71-I78 HydrophobicContact CG1-CD1 3.97Å; V71-I78 HydrophobicContact CG1-CG1 4.39Å; V71-I78 HydrophobicContact CG1-CG2 3.97Å
79I97.1Very high93.3Very high1 Ų154.5 Ų54.51%0.00528%0.28CS..THydrogen-bonded Turntrans-104.910.5179.562.3168.5000112.1T17 L29 L45 H47 E48 T77T17-I79 HydrophobicContact CG2-CD1 4.35Å; T17-I79 HydrophobicContact CG2-CG1 4.46Å; T17-I79 VanDerWaalsContact OG1-CG1 3.27Å; T17-I79 WeakPolarHBondContact OG1-CG1 3.41Å; L29-I79 HydrophobicContact CD1-CD1 3.81Å; L29-I79 HydrophobicContact CD2-CD1 4.19Å; L29-I79 HydrophobicContact CD2-CG1 4.12Å; L29-I79 HydrophobicContact CD2-CG2 3.87Å; L45-I79 HydrophobicContact CB-CG2 3.96Å; L45-I79 HydrophobicContact CD1-CG2 4.05Å; L45-I79 HydrophobicContact CG-CG2 4.46Å; H47-I79 CarbonylContact C-O 3.53Å; H47-I79 WeakPolarHBondContact CA-O 3.45Å; E48-I79 PolarHBondContact N-O 2.78Å; T77-I79 PolarHBondContact O-N 2.78Å; T77-I79 VanDerWaalsContact OG1-CG1 3.24Å; T77-I79 WeakPolarHBondContact OG1-CG1 3.45Å; T77-I79 PolarHBondContact OG1-N 2.83Å
80G95.6Very high93.6Very high14 Ų1456.1 Ų56.114%0.14429%0.288CS..  trans69.3173.9178.700000114.8T17 E48 T77T17-G80 PolarHBondContact OG1-O 2.99Å; E48-G80 WeakPolarHBondContact OE1-CA 3.44Å; T77-G80 VanDerWaalsContact CG2-C 3.5Å; T77-G80 VanDerWaalsContact CG2-O 3.29Å; T77-G80 WeakPolarHBondContact CG2-O 3.42Å; T77-G80 PolarHBondContact O-N 2.74Å
81S94Very high94Very high33 Ų3360.7 Ų60.723%0.23131%0.309CS..  trans-161.288.7179.3-177.10000109.8S18 G19 E48S18-S81 VanDerWaalsContact C-OG 3.28Å; S18-S81 VanDerWaalsContact CA-OG 3.29Å; S18-S81 WeakPolarHBondContact CA-OG 3.3Å; G19-S81 PolarHBondContact N-OG 2.63Å; G19-S81 PolarHBondContact O-OG 2.88Å; E48-S81 PolarHBondContact OE2-N 2.79Å
82A91.3Very high94.1Very high29 Ų2960.5 Ų60.524%0.2431%0.309CS..  trans-90.3148.7-179.600000112.2E48 Q51 C84E48-A82 HydrophobicContact CB-CB 3.95Å; E48-A82 PolarHBondContact O-N 3.16Å; Q51-A82 HydrophobicContact CB-CB 3.8Å; Q51-A82 HydrophobicContact CG-CB 4.35Å; A82-C84 PolarHBondContact O-N 2.89Å
83R89Confident94.2Very high245 Ų24561.8 Ų61.893%0.92531%0.314SS*.  trans-72.2122.2166.5-76.8-171.6-82.4179.4-7109.2
84C91.9Very high94.3Very high20 Ų2062 Ų6214%0.13532%0.315CS..  trans-106.5104.9-179.7-170.30000111.7Q51 A82 F87Q51-C84 HydrophobicContact CB-CB 4.13Å; Q51-C84 PolarHBondContact OE1-SG 3.28Å; A82-C84 PolarHBondContact O-N 2.89Å; C84-F87 HydrophobicContact CB-CB 4.03Å; C84-F87 VanDerWaalsContact SG-CB 3.59Å; C84-F87 PolarHBondContact SG-N 3.01Å
85K92Very high94.4Very high187 Ų18760.7 Ų60.781%0.81331%0.311SS*.SBendtrans-71.5-36172.6-71.1-176.2179.71790111.9F87 M88K85-F87 VanDerWaalsContact C-N 3.29Å; K85-F87 PolarHBondContact O-N 3.09Å; K85-M88 VanDerWaalsContact O-CB 3.32Å; K85-M88 WeakPolarHBondContact O-CB 3.2Å; K85-M88 PolarHBondContact O-N 3.22Å; K85-M88 VanDerWaalsContact O-N 3.13Å
86A93.3Very high94.6Very high37 Ų3759.2 Ų59.231%0.30630%0.301SS..G310 helixtrans-60.8-38.9-17800000111.9V54 M88 T89 G92V54-A86 HydrophobicContact CG1-CB 4.06Å; A86-M88 PolarHBondContact O-N 3.15Å; A86-M88 VanDerWaalsContact O-N 3.1Å; A86-T89 PolarHBondContact O-N 3.08Å; A86-T89 PolarHBondContact O-OG1 3.19Å; A86-G92 WeakPolarHBondContact O-CA 3.43Å
87F94.8Very high94.7Very high13 Ų1358.8 Ų58.86%0.05730%0.296CS..G310 helixtrans-64.8-15.3179.2-159.9-97.1000114Y50 M53 V54 C84 K85 T89 R93 A96 L123Y50-F87 AromaticContact CD1-CD1 3.9Å; Y50-F87 HydrophobicContact CD1-CD1 3.9Å; Y50-F87 AromaticContact CD1-CD2 3.78Å; Y50-F87 HydrophobicContact CD1-CD2 3.78Å; Y50-F87 AromaticContact CD1-CE1 3.66Å; Y50-F87 HydrophobicContact CD1-CE1 3.66Å; Y50-F87 AromaticContact CD1-CE2 3.52Å; Y50-F87 HydrophobicContact CD1-CE2 3.52Å; Y50-F87 AromaticContact CD1-CG 3.95Å; Y50-F87 HydrophobicContact CD1-CG 3.95Å; Y50-F87 AromaticContact CD1-CZ 3.46Å; Y50-F87 HydrophobicContact CD1-CZ 3.46Å; Y50-F87 VanDerWaalsContact CD1-CZ 3.46Å; Y50-F87 HydrophobicContact CD2-CD1 4.36Å; Y50-F87 HydrophobicContact CE1-CD1 4.21Å; Y50-F87 AromaticContact CE1-CE1 3.56Å; Y50-F87 HydrophobicContact CE1-CE1 3.56Å; Y50-F87 AromaticContact CE1-CE2 3.93Å; Y50-F87 HydrophobicContact CE1-CE2 3.93Å; Y50-F87 AromaticContact CE1-CZ 3.39Å; Y50-F87 HydrophobicContact CE1-CZ 3.39Å; Y50-F87 HydrophobicContact CE2-CE1 4.47Å; Y50-F87 AromaticContact CG-CD1 3.99Å; Y50-F87 HydrophobicContact CG-CD1 3.99Å; Y50-F87 HydrophobicContact CG-CD2 4.2Å; Y50-F87 HydrophobicContact CG-CE1 4.18Å; Y50-F87 HydrophobicContact CG-CE2 4.37Å; Y50-F87 AromaticContact CG-CG 4Å; Y50-F87 HydrophobicContact CG-CG 4Å; Y50-F87 HydrophobicContact CG-CZ 4.36Å; Y50-F87 AromaticContact CZ-CE1 3.99Å; M53-F87 HydrophobicContact SD-CE2 4.36Å; V54-F87 HydrophobicContact CG2-CB 4.28Å; V54-F87 HydrophobicContact CG2-CD2 3.82Å; C84-F87 HydrophobicContact CB-CB 4.03Å; C84-F87 VanDerWaalsContact SG-CB 3.59Å; C84-F87 PolarHBondContact SG-N 3.01Å; K85-F87 VanDerWaalsContact C-N 3.29Å; K85-F87 PolarHBondContact O-N 3.09Å; F87-T89 VanDerWaalsContact C-N 3.26Å; F87-T89 PolarHBondContact O-N 3.13Å; F87-R93 HydrophobicContact CD1-CG 4.15Å; F87-R93 HydrophobicContact CD2-CG 4.04Å; F87-R93 HydrophobicContact CE1-CG 4.08Å; F87-R93 HydrophobicContact CE2-CG 3.99Å; F87-R93 HydrophobicContact CG-CG 4.13Å; F87-R93 HydrophobicContact CZ-CG 4.01Å; F87-R93 WeakPolarHBondContact O-CG 3.43Å; F87-R93 PolarHBondContact O-NH1 3.13Å; F87-A96 HydrophobicContact CD2-CB 4.09Å; F87-A96 HydrophobicContact CE2-CB 3.74Å; F87-L123 HydrophobicContact CE2-CD1 4.14Å; F87-L123 HydrophobicContact CE2-CD2 4.42Å; F87-L123 HydrophobicContact CZ-CB 4.06Å; F87-L123 HydrophobicContact CZ-CD1 3.85Å; F87-L123 HydrophobicContact CZ-CD2 3.99Å; F87-L123 HydrophobicContact CZ-CG 4.17Å
88M92.7Very high94.6Very high154 Ų15458.3 Ų58.376%0.75929%0.292SS*.G310 helixtrans-71.7-22.4172.9-58.6-65.7-72.900112K85 A86 R93K85-M88 VanDerWaalsContact O-CB 3.32Å; K85-M88 WeakPolarHBondContact O-CB 3.2Å; K85-M88 PolarHBondContact O-N 3.22Å; K85-M88 VanDerWaalsContact O-N 3.13Å; A86-M88 PolarHBondContact O-N 3.15Å; A86-M88 VanDerWaalsContact O-N 3.1Å; M88-R93 VanDerWaalsContact C-NH1 3.35Å; M88-R93 PolarHBondContact O-NH1 3.02Å
89T95.2Very high94.6Very high65 Ų6555.6 Ų55.640%0.39928%0.278SS..SBendtrans-93156.5177.488.10000111.5A86 F87 E91 G92 R93A86-T89 PolarHBondContact O-N 3.08Å; A86-T89 PolarHBondContact O-OG1 3.19Å; F87-T89 VanDerWaalsContact C-N 3.26Å; F87-T89 PolarHBondContact O-N 3.13Å; T89-E91 VanDerWaalsContact C-N 3.28Å; T89-E91 VanDerWaalsContact CB-OE2 3.25Å; T89-E91 WeakPolarHBondContact CB-OE2 3.46Å; T89-E91 PolarHBondContact O-N 3.03Å; T89-E91 PolarHBondContact OG1-N 3.38Å; T89-E91 PolarHBondContact OG1-OE2 2.75Å; T89-G92 PolarHBondContact O-N 3.02Å; T89-G92 PolarHBondContact OG1-N 3.47Å; T89-R93 PolarHBondContact O-N 3.33Å; T89-R93 VanDerWaalsContact O-N 3.16Å; T89-R93 PolarHBondContact O-NH1 2.75Å
90V95.1Very high94.6Very high75 Ų7555.6 Ų55.646%0.45528%0.278SS..Hα-helixtrans-61.9-40.4177.6178.40000110G92 R93 Q94V90-G92 PolarHBondContact O-N 2.96Å; V90-R93 PolarHBondContact O-N 3.48Å; V90-Q94 WeakPolarHBondContact O-CB 3.4Å; V90-Q94 PolarHBondContact O-N 3.31Å
91E95.1Very high94.5Very high133 Ų13355 Ų5562%0.62127%0.272SS*.Hα-helixtrans-63.8-40.9179.8-57.477.3-167.800112T89 Q94 K95T89-E91 VanDerWaalsContact C-N 3.28Å; T89-E91 VanDerWaalsContact CB-OE2 3.25Å; T89-E91 WeakPolarHBondContact CB-OE2 3.46Å; T89-E91 PolarHBondContact O-N 3.03Å; T89-E91 PolarHBondContact OG1-N 3.38Å; T89-E91 PolarHBondContact OG1-OE2 2.75Å; E91-Q94 PolarHBondContact O-N 3.25Å; E91-K95 PolarHBondContact O-N 3.42Å
92G96.2Very high94.4Very high7 Ų758 Ų587%0.07228%0.284CS..Hα-helixtrans-65.5-43.5176.500000111.9A86 T89 V90 Q94 K95 A96A86-G92 WeakPolarHBondContact O-CA 3.43Å; T89-G92 PolarHBondContact O-N 3.02Å; T89-G92 PolarHBondContact OG1-N 3.47Å; V90-G92 PolarHBondContact O-N 2.96Å; G92-Q94 VanDerWaalsContact C-N 3.32Å; G92-Q94 PolarHBondContact O-N 3.25Å; G92-K95 PolarHBondContact O-N 3.12Å; G92-A96 PolarHBondContact O-N 3.5Å
93R96.9Very high94.5Very high28 Ų2858.8 Ų58.811%0.10628%0.283CS..Hα-helixtrans-62.5-40.9173.8-66-166.5-63.8-83.411.3111.7F87 M88 T89 V90 K95 A96 V97 L123 E126F87-R93 HydrophobicContact CD1-CG 4.15Å; F87-R93 HydrophobicContact CD2-CG 4.04Å; F87-R93 HydrophobicContact CE1-CG 4.08Å; F87-R93 HydrophobicContact CE2-CG 3.99Å; F87-R93 HydrophobicContact CG-CG 4.13Å; F87-R93 HydrophobicContact CZ-CG 4.01Å; F87-R93 WeakPolarHBondContact O-CG 3.43Å; F87-R93 PolarHBondContact O-NH1 3.13Å; M88-R93 VanDerWaalsContact C-NH1 3.35Å; M88-R93 PolarHBondContact O-NH1 3.02Å; T89-R93 PolarHBondContact O-N 3.33Å; T89-R93 VanDerWaalsContact O-N 3.16Å; T89-R93 PolarHBondContact O-NH1 2.75Å; V90-R93 PolarHBondContact O-N 3.48Å; R93-K95 VanDerWaalsContact C-N 3.33Å; R93-K95 PolarHBondContact O-N 3.23Å; R93-A96 WeakPolarHBondContact O-CB 3.31Å; R93-A96 PolarHBondContact O-N 2.83Å; R93-A96 VanDerWaalsContact O-N 3.16Å; R93-V97 WeakPolarHBondContact O-CG2 3.41Å; R93-V97 PolarHBondContact O-N 3.31Å; R93-L123 HydrophobicContact CB-CD1 4.16Å; R93-E126 IonicContact CZ-OE1 2.75Å; R93-E126 IonicContact CZ-OE2 2.78Å; R93-E126 IonicContact NE-OE1 3.81Å; R93-E126 IonicContact NE-OE2 2.78Å; R93-E126 PolarHBondContact NE-OE2 3.44Å; R93-E126 IonicContact NH2-OE1 3.16Å; R93-E126 PolarHBondContact NH2-OE1 3.45Å; R93-E126 IonicContact NH2-OE2 3.1Å; R93-E126 PolarHBondContact NH2-OE2 3.01Å; R93-E126 VanDerWaalsContact NH2-OE2 3.09Å
94Q96Very high94.6Very high21 Ų2148 Ų4810%0.09825%0.248CC..Hα-helixtrans-61.5-41.1176.7-167.1179.8-18.600111.8V90 E91 G92 V97 E98 L134V90-Q94 WeakPolarHBondContact O-CB 3.4Å; V90-Q94 PolarHBondContact O-N 3.31Å; E91-Q94 PolarHBondContact O-N 3.25Å; G92-Q94 VanDerWaalsContact C-N 3.32Å; G92-Q94 PolarHBondContact O-N 3.25Å; Q94-V97 PolarHBondContact O-N 3.43Å; Q94-E98 PolarHBondContact O-N 3.37Å; Q94-L134 HydrophobicContact CG-CD1 4.07Å; Q94-L134 HydrophobicContact CG-CD2 3.7Å; Q94-L134 HydrophobicContact CG-CG 3.63Å
95K96.7Very high94.7Very high72 Ų7247.1 Ų47.131%0.31324%0.242SC..Hα-helixtrans-65.2-38.7174.2-165.4-179.3176.1-150.90112.2V54 E91 G92 R93 E98 N99V54-K95 HydrophobicContact CG1-CB 4.44Å; V54-K95 HydrophobicContact CG1-CD 4.04Å; V54-K95 WeakPolarHBondContact O-CD 3.36Å; V54-K95 WeakPolarHBondContact O-CE 3.39Å; V54-K95 WeakPolarHBondContact O-CG 3.23Å; V54-K95 PolarHBondContact O-NZ 2.87Å; V54-K95 VanDerWaalsContact O-NZ 3.15Å; E91-K95 PolarHBondContact O-N 3.42Å; G92-K95 PolarHBondContact O-N 3.12Å; R93-K95 VanDerWaalsContact C-N 3.33Å; R93-K95 PolarHBondContact O-N 3.23Å; K95-E98 WeakPolarHBondContact O-CB 3.27Å; K95-E98 PolarHBondContact O-N 3.16Å; K95-N99 PolarHBondContact O-N 3.17Å; K95-N99 PolarHBondContact O-ND2 2.85Å
96A96.9Very high94.6Very high0 Ų038.8 Ų38.80%021%0.207CC..Hα-helixtrans-62.5-43.7173.800000112.5M53 V54 F87 G92 R93 E98 N99 L100M53-A96 HydrophobicContact CB-CB 4.48Å; M53-A96 HydrophobicContact CG-CB 3.85Å; M53-A96 WeakPolarHBondContact O-CA 3.29Å; M53-A96 HydrophobicContact SD-CB 4.04Å; V54-A96 HydrophobicContact CG2-CB 4.07Å; F87-A96 HydrophobicContact CD2-CB 4.09Å; F87-A96 HydrophobicContact CE2-CB 3.74Å; G92-A96 PolarHBondContact O-N 3.5Å; R93-A96 WeakPolarHBondContact O-CB 3.31Å; R93-A96 PolarHBondContact O-N 2.83Å; R93-A96 VanDerWaalsContact O-N 3.16Å; A96-E98 VanDerWaalsContact C-N 3.34Å; A96-E98 PolarHBondContact O-N 3.25Å; A96-N99 PolarHBondContact O-N 2.84Å; A96-L100 WeakPolarHBondContact O-CG 3.42Å; A96-L100 PolarHBondContact O-N 2.88Å
97V95.8Very high94.6Very high0 Ų037 Ų370%019%0.193CC..Hα-helixtrans-59-46.1175.1171.80000111R93 Q94 N99 L100 V101 L123 W127 H130 L131 L134R93-V97 WeakPolarHBondContact O-CG2 3.41Å; R93-V97 PolarHBondContact O-N 3.31Å; Q94-V97 PolarHBondContact O-N 3.43Å; V97-N99 PolarHBondContact O-N 2.9Å; V97-L100 PolarHBondContact O-N 3.04Å; V97-V101 HydrophobicContact CG1-CG2 4.37Å; V97-V101 VanDerWaalsContact O-CG2 3.28Å; V97-V101 WeakPolarHBondContact O-CG2 3.32Å; V97-V101 PolarHBondContact O-N 2.84Å; V97-L123 HydrophobicContact CG2-CD1 3.8Å; V97-W127 HydrophobicContact CB-CE3 4.32Å; V97-W127 HydrophobicContact CB-CZ3 3.99Å; V97-W127 HydrophobicContact CG1-CD2 4.39Å; V97-W127 HydrophobicContact CG1-CE3 3.94Å; V97-W127 HydrophobicContact CG1-CH2 3.91Å; V97-W127 HydrophobicContact CG1-CZ2 4.34Å; V97-W127 HydrophobicContact CG1-CZ3 3.71Å; V97-W127 HydrophobicContact CG2-CE3 3.63Å; V97-W127 HydrophobicContact CG2-CZ3 3.65Å; V97-H130 HydrophobicContact CB-CB 4.11Å; V97-H130 HydrophobicContact CG1-CB 4.07Å; V97-H130 HydrophobicContact CG2-CB 3.79Å; V97-L131 HydrophobicContact CG1-CD2 3.88Å; V97-L131 HydrophobicContact CG1-CG 4.35Å; V97-L134 HydrophobicContact CB-CD1 4.11Å; V97-L134 HydrophobicContact CG1-CD1 3.78Å
98E95.5Very high94.7Very high17 Ų1736.4 Ų36.48%0.07919%0.19CC..Hα-helixtrans-57.6-48.3176.8-177.2-173.6-166.800112.2Q94 K95 A96 L100 V101 I102 L134 R139 L140Q94-E98 PolarHBondContact O-N 3.37Å; K95-E98 WeakPolarHBondContact O-CB 3.27Å; K95-E98 PolarHBondContact O-N 3.16Å; A96-E98 VanDerWaalsContact C-N 3.34Å; A96-E98 PolarHBondContact O-N 3.25Å; E98-L100 VanDerWaalsContact C-N 3.34Å; E98-L100 PolarHBondContact O-N 3.2Å; E98-V101 PolarHBondContact O-N 3.48Å; E98-I102 HydrophobicContact CG-CD1 3.9Å; E98-I102 VanDerWaalsContact O-CG1 3.29Å; E98-I102 WeakPolarHBondContact O-CG1 3.27Å; E98-I102 PolarHBondContact O-N 2.82Å; E98-L134 HydrophobicContact CB-CD1 3.92Å; E98-L134 HydrophobicContact CB-CD2 3.95Å; E98-L134 HydrophobicContact CG-CD2 4.29Å; E98-R139 VanDerWaalsContact CD-NE 3.3Å; E98-R139 IonicContact OE1-CZ 2.97Å; E98-R139 IonicContact OE1-NE 3.52Å; E98-R139 PolarHBondContact OE1-NE 2.94Å; E98-R139 IonicContact OE1-NH2 2.57Å; E98-R139 PolarHBondContact OE1-NH2 2.69Å; E98-R139 IonicContact OE2-CZ 3.43Å; E98-R139 IonicContact OE2-NE 2.64Å; E98-R139 PolarHBondContact OE2-NE 2.96Å; E98-R139 IonicContact OE2-NH1 2.75Å; E98-R139 PolarHBondContact OE2-NH1 3.41Å; E98-R139 IonicContact OE2-NH2 3.06Å; E98-R139 PolarHBondContact OE2-NH2 2.94Å; E98-L140 HydrophobicContact CG-CD2 4.28Å; E98-L140 HydrophobicContact CG-CG 4.49Å
99N96.5Very high95Very high17 Ų1729.1 Ų29.19%0.09115%0.154CC..Hα-helixtrans-62-40.3179-69.4-28.3000112.4M53 V54 G56 F60 K95 A96 V97 I102 H103M53-N99 PolarHBondContact O-ND2 3.3Å; V54-N99 PolarHBondContact O-ND2 2.8Å; G56-N99 VanDerWaalsContact CA-ND2 3.32Å; G56-N99 WeakPolarHBondContact CA-ND2 3.45Å; G56-N99 PolarHBondContact N-ND2 2.9Å; F60-N99 HydrophobicContact CE2-CB 4.04Å; F60-N99 HydrophobicContact CZ-CB 4.07Å; K95-N99 PolarHBondContact O-N 3.17Å; K95-N99 PolarHBondContact O-ND2 2.85Å; A96-N99 PolarHBondContact O-N 2.84Å; V97-N99 PolarHBondContact O-N 2.9Å; N99-I102 PolarHBondContact O-N 3.5Å; N99-H103 PolarHBondContact O-N 2.7Å; N99-H103 PolarHBondContact O-ND1 3.32Å
100L95.8Very high95.1Very high0 Ų026 Ų260%014%0.135CC..Hα-helixtrans-61.6-44.2175.2-71.6166.5000111.3I46 M53 F60 A96 V97 E98 H103 G104 I105 L108 L123 W127I46-L100 HydrophobicContact CD1-CD2 4.04Å; M53-L100 HydrophobicContact CG-CD1 4.44Å; M53-L100 HydrophobicContact CG-CG 4.34Å; M53-L100 HydrophobicContact SD-CD1 3.97Å; M53-L100 HydrophobicContact SD-CG 4.46Å; F60-L100 HydrophobicContact CE1-CD2 4.03Å; F60-L100 HydrophobicContact CZ-CD2 4.36Å; A96-L100 WeakPolarHBondContact O-CG 3.42Å; A96-L100 PolarHBondContact O-N 2.88Å; V97-L100 PolarHBondContact O-N 3.04Å; E98-L100 VanDerWaalsContact C-N 3.34Å; E98-L100 PolarHBondContact O-N 3.2Å; L100-H103 PolarHBondContact O-N 3Å; L100-G104 PolarHBondContact O-N 3.02Å; L100-I105 HydrophobicContact CD2-CB 4.07Å; L100-I105 HydrophobicContact CD2-CD1 4.2Å; L100-I105 HydrophobicContact CD2-CG2 3.84Å; L100-I105 PolarHBondContact O-N 3.05Å; L100-L108 HydrophobicContact CD1-CD2 4.47Å; L100-L108 HydrophobicContact CD2-CD1 4.11Å; L100-L123 HydrophobicContact CD1-CD2 4.38Å; L100-W127 HydrophobicContact CB-CH2 4.09Å; L100-W127 HydrophobicContact CD1-CH2 4.24Å; L100-W127 HydrophobicContact CD1-CZ3 3.87Å
101V93.8Very high95.3Very high3 Ų322.4 Ų22.42%0.01811%0.113CC..Hα-helixtrans-66.6-38.6179.4171.10000111.9V97 E98 H103 G104 W127 L131 L140 Q144 V145 L148V97-V101 HydrophobicContact CG1-CG2 4.37Å; V97-V101 VanDerWaalsContact O-CG2 3.28Å; V97-V101 WeakPolarHBondContact O-CG2 3.32Å; V97-V101 PolarHBondContact O-N 2.84Å; E98-V101 PolarHBondContact O-N 3.48Å; V101-H103 VanDerWaalsContact C-N 3.28Å; V101-H103 PolarHBondContact O-N 2.82Å; V101-G104 PolarHBondContact O-N 2.98Å; V101-W127 HydrophobicContact CG2-CH2 4.11Å; V101-W127 HydrophobicContact CG2-CZ2 4.02Å; V101-L131 HydrophobicContact CG2-CD2 3.77Å; V101-L140 HydrophobicContact CB-CD1 3.98Å; V101-L140 HydrophobicContact CB-CD2 4.12Å; V101-L140 HydrophobicContact CG1-CD1 3.76Å; V101-L140 HydrophobicContact CG1-CD2 3.6Å; V101-L140 HydrophobicContact CG1-CG 4.29Å; V101-L140 HydrophobicContact CG2-CD1 4.1Å; V101-Q144 HydrophobicContact CG1-CG 4.16Å; V101-Q144 PolarHBondContact O-NE2 3.1Å; V101-Q144 VanDerWaalsContact O-NE2 3.08Å; V101-V145 HydrophobicContact CG1-CG2 4.45Å; V101-L148 HydrophobicContact CB-CD1 4.41Å; V101-L148 HydrophobicContact CG1-CD1 3.66Å; V101-L148 WeakPolarHBondContact O-CD1 3.32Å
102I92.4Very high95.3Very high95 Ų9516.1 Ų16.149%0.4878%0.084SC..Hα-helixtrans-59.7-39.2176-72.5167000111.2E98 N99 G104 L140E98-I102 HydrophobicContact CG-CD1 3.9Å; E98-I102 VanDerWaalsContact O-CG1 3.29Å; E98-I102 WeakPolarHBondContact O-CG1 3.27Å; E98-I102 PolarHBondContact O-N 2.82Å; N99-I102 PolarHBondContact O-N 3.5Å; I102-G104 VanDerWaalsContact C-N 3.26Å; I102-G104 PolarHBondContact O-N 3.14Å; I102-L140 HydrophobicContact CG1-CD2 4.5Å
103H92.8Very high95.2Very high45 Ų4516.1 Ų16.121%0.2088%0.084CC..THydrogen-bonded Turntrans-83.80.4176.4-65.785.3000113.5F44 F60 N99 L100 V101 I105F44-H103 AromaticContact CE1-CD2 3.94Å; F60-H103 WeakPolarHBondContact CB-NE2 3.34Å; F60-H103 HydrophobicContact CD1-CB 4.42Å; F60-H103 AromaticContact CD1-CG 3.92Å; F60-H103 AromaticContact CD1-ND1 3.85Å; F60-H103 AromaticContact CD2-CE1 3.94Å; F60-H103 AromaticContact CG-CE1 3.69Å; F60-H103 AromaticContact CG-ND1 3.86Å; F60-H103 AromaticContact CG-NE2 3.9Å; N99-H103 PolarHBondContact O-N 2.7Å; N99-H103 PolarHBondContact O-ND1 3.32Å; L100-H103 PolarHBondContact O-N 3Å; V101-H103 VanDerWaalsContact C-N 3.28Å; V101-H103 PolarHBondContact O-N 2.82Å; H103-I105 HydrophobicContact CB-CD1 3.76Å; H103-I105 HydrophobicContact CB-CG1 3.94Å; H103-I105 PolarHBondContact O-N 3.46Å
104G92.3Very high95Very high19 Ų1915.3 Ų15.320%0.1968%0.082CC..THydrogen-bonded Turntrans67.621.7-17800000114.5S12 L100 V101 I102 L148S12-G104 WeakPolarHBondContact CB-O 3.46Å; L100-G104 PolarHBondContact O-N 3.02Å; V101-G104 PolarHBondContact O-N 2.98Å; I102-G104 VanDerWaalsContact C-N 3.26Å; I102-G104 PolarHBondContact O-N 3.14Å; G104-L148 VanDerWaalsContact C-CD2 3.49Å; G104-L148 VanDerWaalsContact O-CD2 3.29Å; G104-L148 WeakPolarHBondContact O-CD2 3.4Å
105I94Very high94.7Very high1 Ų116.4 Ų16.41%0.00510%0.099CC..EExtended strand (participates in β ladder)trans-80.6122.4-176.6-64.5166.9000109.8F44 F60 L100 H103 D107F44-I105 HydrophobicContact CB-CD1 3.8Å; F44-I105 HydrophobicContact CD2-CD1 4Å; F44-I105 HydrophobicContact CD2-CG1 3.99Å; F44-I105 HydrophobicContact CG-CD1 3.94Å; F44-I105 HydrophobicContact CG-CG1 4.44Å; F60-I105 HydrophobicContact CD1-CD1 3.72Å; F60-I105 HydrophobicContact CE1-CD1 3.7Å; L100-I105 HydrophobicContact CD2-CB 4.07Å; L100-I105 HydrophobicContact CD2-CD1 4.2Å; L100-I105 HydrophobicContact CD2-CG2 3.84Å; L100-I105 PolarHBondContact O-N 3.05Å; H103-I105 HydrophobicContact CB-CD1 3.76Å; H103-I105 HydrophobicContact CB-CG1 3.94Å; H103-I105 PolarHBondContact O-N 3.46Å; I105-D107 WeakPolarHBondContact CG2-O 3.36Å
106T89.2Confident94.7Very high13 Ų1313.4 Ų13.48%0.089%0.087CC..EExtended strand (participates in β ladder)trans-126.5-14.4179.861.90000112.4S12 L148 R152S12-T106 PolarHBondContact O-N 3.39Å; T106-L148 HydrophobicContact CG2-CB 3.85Å; T106-L148 HydrophobicContact CG2-CD2 3.5Å; T106-L148 VanDerWaalsContact CG2-CD2 3.5Å; T106-L148 HydrophobicContact CG2-CG 4.31Å; T106-L148 WeakPolarHBondContact CG2-O 3.42Å; T106-R152 PolarHBondContact O-N 3.48Å; T106-R152 PolarHBondContact OG1-NH2 3.02Å
107D94.1Very high94.6Very high0 Ų013.4 Ų13.40%09%0.087CC..EExtended strand (participates in β ladder)trans-112122.5175.3-80.7-40.8000108M13 G14 Y41 I105 R152 L319M13-D107 CarbonylContact C-O 3.56Å; M13-D107 VanDerWaalsContact CA-O 3.22Å; M13-D107 WeakPolarHBondContact CA-O 3.46Å; M13-D107 HydrophobicContact CB-CB 4.11Å; M13-D107 HydrophobicContact CE-CB 4.42Å; M13-D107 HydrophobicContact CG-CB 4.15Å; G14-D107 PolarHBondContact N-O 2.94Å; Y41-D107 HydrophobicContact CE1-CB 4.2Å; Y41-D107 WeakPolarHBondContact CE1-OD2 3.47Å; Y41-D107 PolarHBondContact OH-OD2 3.35Å; I105-D107 WeakPolarHBondContact CG2-O 3.36Å; D107-R152 VanDerWaalsContact OD1-CB 3.28Å; D107-R152 WeakPolarHBondContact OD1-CB 3.46Å; D107-R152 IonicContact OD1-CZ 2.84Å; D107-R152 IonicContact OD1-NE 3.23Å; D107-R152 PolarHBondContact OD1-NE 3.44Å; D107-R152 VanDerWaalsContact OD1-NE 3.12Å; D107-R152 IonicContact OD1-NH1 2.87Å; D107-R152 PolarHBondContact OD1-NH1 2.91Å; D107-R152 IonicContact OD1-NH2 3.34Å; D107-R152 PolarHBondContact OD1-NH2 3.03Å; D107-R152 IonicContact OD2-CZ 3.5Å; D107-R152 IonicContact OD2-NH1 3.42Å; D107-R152 PolarHBondContact OD2-NH1 3.43Å; D107-R152 VanDerWaalsContact OD2-NH1 3.14Å; D107-R152 IonicContact OD2-NH2 2.82Å; D107-R152 PolarHBondContact OD2-NH2 3.15Å; D107-L319 HydrophobicContact CB-CD1 4.15Å; D107-L319 HydrophobicContact CB-CD2 4.33Å
108L96.6Very high94.4Very high0 Ų015.2 Ų15.20%010%0.098CC..EExtended strand (participates in β ladder)trans-129.3125.5-175.5-168.468.2000111.4G14 F16 I46 M53 L100 L120 L151 R152 I153 V154G14-L108 WeakPolarHBondContact O-CA 3.37Å; F16-L108 HydrophobicContact CD1-CD1 3.91Å; F16-L108 HydrophobicContact CD1-CD2 4.49Å; F16-L108 HydrophobicContact CD1-CG 4.15Å; F16-L108 HydrophobicContact CE1-CD1 4.03Å; F16-L108 HydrophobicContact CE1-CD2 3.8Å; F16-L108 HydrophobicContact CE1-CG 3.78Å; I46-L108 HydrophobicContact CD1-CD1 3.82Å; M53-L108 HydrophobicContact CE-CD1 4.28Å; M53-L108 HydrophobicContact CE-CD2 4.02Å; L100-L108 HydrophobicContact CD1-CD2 4.47Å; L100-L108 HydrophobicContact CD2-CD1 4.11Å; L108-L120 HydrophobicContact CD2-CD1 3.67Å; L108-L120 HydrophobicContact CG-CD1 4.33Å; L108-L151 HydrophobicContact CB-CD1 4.11Å; L108-R152 PolarHBondContact N-O 3.46Å; L108-I153 HydrophobicContact CB-CG2 4.38Å; L108-I153 CarbonylContact O-C 3.53Å; L108-I153 VanDerWaalsContact O-CA 3.31Å; L108-I153 WeakPolarHBondContact O-CA 3.28Å; L108-V154 PolarHBondContact O-N 2.9Å
109V98.2Very high94.3Very high0 Ų015.1 Ų15.10%010%0.102CC..EExtended strand (participates in β ladder)trans-108.1119.5174-176.20000109.7M13 G14 V15 F16 V32 V154 L156 A315 L319M13-V109 HydrophobicContact SD-CG2 3.97Å; G14-V109 PolarHBondContact O-N 3.47Å; V15-V109 WeakPolarHBondContact CA-O 3.33Å; V15-V109 HydrophobicContact CB-CB 4.37Å; V15-V109 HydrophobicContact CG2-CB 4.16Å; V15-V109 HydrophobicContact CG2-CG1 4.36Å; F16-V109 WeakPolarHBondContact CD1-O 3.49Å; F16-V109 PolarHBondContact N-O 2.88Å; F16-V109 VanDerWaalsContact N-O 3.12Å; V32-V109 HydrophobicContact CG1-CB 4.17Å; V32-V109 HydrophobicContact CG1-CG1 4.4Å; V32-V109 HydrophobicContact CG1-CG2 3.94Å; V32-V109 HydrophobicContact CG2-CG1 3.94Å; V109-V154 WeakPolarHBondContact CA-O 3.29Å; V109-L156 HydrophobicContact CG1-CD1 4.15Å; V109-L156 HydrophobicContact CG1-CG 4.25Å; V109-A315 HydrophobicContact CG1-CB 4.27Å; V109-A315 HydrophobicContact CG2-CB 4.5Å; V109-L319 HydrophobicContact CG2-CD1 3.46Å; V109-L319 VanDerWaalsContact CG2-CD1 3.46Å
110C98Very high94.2Very high0 Ų014.3 Ų14.30%010%0.097CC..EExtended strand (participates in β ladder)trans-101.3127174.2-179.90000110.1F16 L117 L120 V154 L156F16-C110 HydrophobicContact CD1-CB 4.42Å; F16-C110 HydrophobicContact CE1-CB 3.6Å; F16-C110 HydrophobicContact CE2-CB 4.37Å; F16-C110 HydrophobicContact CZ-CB 3.58Å; F16-C110 WeakPolarHBondContact CZ-SG 3.34Å; C110-L117 HydrophobicContact CB-CD2 4.08Å; C110-L120 HydrophobicContact CB-CD1 4.1Å; C110-L120 HydrophobicContact CB-CD2 3.46Å; C110-L120 VanDerWaalsContact CB-CD2 3.46Å; C110-L120 HydrophobicContact CB-CG 4.23Å; C110-V154 PolarHBondContact N-O 2.8Å; C110-L156 PolarHBondContact O-N 3.25Å
111I98.3Very high94Very high0 Ų014.9 Ų14.90%010%0.1CC..EExtended strand (participates in β ladder)trans-110.2108.2171-54.1167.2000107.8V15 F16 T17 S18 M25 A28 L29 L156V15-I111 HydrophobicContact CG2-CD1 3.95Å; V15-I111 HydrophobicContact CG2-CG1 4.49Å; F16-I111 PolarHBondContact O-N 3.41Å; T17-I111 CarbonylContact C-O 3.47Å; T17-I111 VanDerWaalsContact CA-O 3.24Å; T17-I111 WeakPolarHBondContact CA-O 3.36Å; T17-I111 HydrophobicContact CG2-CB 3.88Å; T17-I111 HydrophobicContact CG2-CD1 4.34Å; T17-I111 HydrophobicContact CG2-CG2 4.19Å; S18-I111 PolarHBondContact N-O 3.46Å; M25-I111 HydrophobicContact CB-CG2 4.24Å; M25-I111 HydrophobicContact CG-CG2 3.83Å; A28-I111 HydrophobicContact CB-CD1 3.75Å; A28-I111 HydrophobicContact CB-CG1 4.33Å; A28-I111 HydrophobicContact CB-CG2 4.4Å; L29-I111 HydrophobicContact CB-CD1 4.18Å; I111-L156 WeakPolarHBondContact CA-O 3.36Å; I111-L156 HydrophobicContact CG1-CB 4.15Å; I111-L156 HydrophobicContact CG1-CD1 4.04Å; I111-L156 HydrophobicContact CG1-CG 4.5Å; I111-L156 HydrophobicContact CG2-CB 4.5Å
112G96.3Very high94Very high0 Ų017.7 Ų17.70%012%0.115CC..EExtended strand (participates in β ladder)trans-176.5-175.5-175.600000115.1S18 L156 V157 G158S18-G112 WeakPolarHBondContact O-CA 3.26Å; G112-L156 PolarHBondContact N-O 2.88Å; G112-V157 CarbonylContact O-C 3.6Å; G112-V157 WeakPolarHBondContact O-CA 3.36Å; G112-G158 CarbonylContact C-O 3.6Å; G112-G158 VanDerWaalsContact C-O 3.29Å; G112-G158 PolarHBondContact O-N 2.94Å
113G94.1Very high94Very high8 Ų813.2 Ų13.28%0.0829%0.091CC..  trans-79.2-174.7178.900000113.8G115 S116 L117 G158G113-G115 VanDerWaalsContact C-N 3.34Å; G113-G115 PolarHBondContact O-N 3.29Å; G113-S116 PolarHBondContact O-N 3.35Å; G113-L117 PolarHBondContact O-N 2.69Å; G113-L117 VanDerWaalsContact O-N 3.08Å; G113-G158 PolarHBondContact N-O 2.78Å
114D91Very high94Very high10 Ų1013.6 Ų13.65%0.0539%0.091CC..Hα-helixtrans-52.2-47178.771-48.3000113.4S116 L117 T118 F164 R205 T353 K357D114-S116 PolarHBondContact O-N 3.06Å; D114-L117 PolarHBondContact O-N 3.24Å; D114-T118 WeakPolarHBondContact O-CB 3.48Å; D114-T118 PolarHBondContact O-N 3.01Å; D114-T118 PolarHBondContact O-OG1 3.09Å; D114-F164 HydrophobicContact CB-CD2 4Å; D114-R205 IonicContact OD1-NH1 3.52Å; D114-R205 PolarHBondContact OD1-NH1 2.91Å; D114-T353 HydrophobicContact CB-CG2 4.26Å; D114-K357 IonicContact OD2-NZ 3.38Å; D114-K357 PolarHBondContact OD2-NZ 3.45Å
115G91.1Very high93.9Very high45 Ų4518.6 Ų18.646%0.46411%0.109SC..Hα-helixtrans-64.4-39-179.700000113G113 T118 G119G113-G115 VanDerWaalsContact C-N 3.34Å; G113-G115 PolarHBondContact O-N 3.29Å; G115-T118 PolarHBondContact O-N 3.46Å; G115-G119 PolarHBondContact O-N 2.69Å
116S95.1Very high93.8Very high8 Ų821.4 Ų21.46%0.05612%0.123CC..Hα-helixtrans-67.3-44.9178.3-59.30000111.2S18 G19 Y50 G113 D114 T118 G119 L120S18-S116 VanDerWaalsContact CB-OG 3.23Å; S18-S116 WeakPolarHBondContact CB-OG 3.47Å; S18-S116 PolarHBondContact O-OG 3Å; S18-S116 PolarHBondContact OG-OG 3.46Å; G19-S116 PolarHBondContact N-OG 3.24Å; Y50-S116 PolarHBondContact OH-O 3.07Å; G113-S116 PolarHBondContact O-N 3.35Å; D114-S116 PolarHBondContact O-N 3.06Å; S116-T118 VanDerWaalsContact C-N 3.3Å; S116-T118 PolarHBondContact O-N 3.02Å; S116-G119 PolarHBondContact O-N 3.3Å; S116-L120 PolarHBondContact O-N 3.4Å
117L95Very high94Very high0 Ų021.4 Ų21.40%012%0.121CC..Hα-helixtrans-66.6-32.9177.4-66.3-174.8000112.7C110 G113 D114 L120 N121 G155 V157 F164 V333 L346C110-L117 HydrophobicContact CB-CD2 4.08Å; G113-L117 PolarHBondContact O-N 2.69Å; G113-L117 VanDerWaalsContact O-N 3.08Å; D114-L117 PolarHBondContact O-N 3.24Å; L117-L120 HydrophobicContact CD2-CD2 4.41Å; L117-L120 PolarHBondContact O-N 2.84Å; L117-N121 PolarHBondContact O-N 2.81Å; L117-G155 VanDerWaalsContact CD2-CA 3.48Å; L117-V157 HydrophobicContact CD1-CB 4.35Å; L117-V157 HydrophobicContact CD1-CG1 4.46Å; L117-V157 HydrophobicContact CD1-CG2 3.69Å; L117-F164 HydrophobicContact CB-CE2 4.29Å; L117-F164 HydrophobicContact CD1-CD2 4.43Å; L117-F164 HydrophobicContact CD1-CE1 4.42Å; L117-F164 HydrophobicContact CD1-CE2 3.9Å; L117-F164 HydrophobicContact CD1-CZ 3.89Å; L117-V333 HydrophobicContact CD1-CG2 4.16Å; L117-L346 HydrophobicContact CB-CD1 3.83Å; L117-L346 HydrophobicContact CD1-CD1 4.41Å
118T92.1Very high93.8Very high39 Ų3924.9 Ų24.924%0.23915%0.15CC..Hα-helixtrans-63.1-47.9170.8-55.30000110.9D114 G115 S116 L120 N121 I122 V350D114-T118 WeakPolarHBondContact O-CB 3.48Å; D114-T118 PolarHBondContact O-N 3.01Å; D114-T118 PolarHBondContact O-OG1 3.09Å; G115-T118 PolarHBondContact O-N 3.46Å; S116-T118 VanDerWaalsContact C-N 3.3Å; S116-T118 PolarHBondContact O-N 3.02Å; T118-L120 VanDerWaalsContact C-N 3.3Å; T118-L120 PolarHBondContact O-N 3.01Å; T118-N121 PolarHBondContact O-N 2.88Å; T118-I122 HydrophobicContact CG2-CD1 4.18Å; T118-I122 WeakPolarHBondContact O-CG1 3.3Å; T118-I122 PolarHBondContact O-N 3.44Å; T118-I122 VanDerWaalsContact O-N 3.08Å; T118-V350 HydrophobicContact CG2-CG1 4.05Å
119G93.8Very high93.6Very high15 Ų1527.2 Ų27.216%0.15517%0.173CC..Hα-helixtrans-60.7-37.5176.500000113.1G115 S116 I122 L123G115-G119 PolarHBondContact O-N 2.69Å; S116-G119 PolarHBondContact O-N 3.3Å; G119-I122 PolarHBondContact O-N 2.86Å; G119-L123 PolarHBondContact O-N 3.28Å
120L94.6Very high93.4Very high0 Ų027.7 Ų27.70%018%0.176CC..Hα-helixtrans-63.7-43.6175.4-173.172.8000111.7F16 Y50 L108 C110 S116 L117 T118 L123 R124 I153 L346F16-L120 HydrophobicContact CE1-CD1 4.08Å; F16-L120 HydrophobicContact CZ-CD1 4.07Å; Y50-L120 WeakPolarHBondContact OH-CA 3.26Å; Y50-L120 PolarHBondContact OH-N 3.15Å; L108-L120 HydrophobicContact CD2-CD1 3.67Å; L108-L120 HydrophobicContact CG-CD1 4.33Å; C110-L120 HydrophobicContact CB-CD1 4.1Å; C110-L120 HydrophobicContact CB-CD2 3.46Å; C110-L120 VanDerWaalsContact CB-CD2 3.46Å; C110-L120 HydrophobicContact CB-CG 4.23Å; S116-L120 PolarHBondContact O-N 3.4Å; L117-L120 HydrophobicContact CD2-CD2 4.41Å; L117-L120 PolarHBondContact O-N 2.84Å; T118-L120 VanDerWaalsContact C-N 3.3Å; T118-L120 PolarHBondContact O-N 3.01Å; L120-L123 PolarHBondContact O-N 2.96Å; L120-R124 PolarHBondContact O-N 3.45Å; L120-R124 VanDerWaalsContact O-N 3.11Å; L120-I153 HydrophobicContact CD1-CB 4.32Å; L120-I153 HydrophobicContact CD1-CG2 4.06Å; L120-I153 HydrophobicContact CD2-CB 3.93Å; L120-I153 HydrophobicContact CD2-CD1 3.97Å; L120-I153 HydrophobicContact CD2-CG1 4.28Å; L120-I153 HydrophobicContact CG-CB 4.06Å; L120-I153 HydrophobicContact CG-CD1 3.76Å; L120-I153 HydrophobicContact CG-CG1 4.41Å; L120-I153 HydrophobicContact CG-CG2 4.17Å; L120-L346 HydrophobicContact CD2-CD2 4.33Å
121N91.7Very high93.1Very high11 Ų1128.5 Ų28.56%0.05918%0.18CC..Hα-helixtrans-63-44.2178.2-169.245.2000111.5L117 T118 R124 Q125 L346L117-N121 PolarHBondContact O-N 2.81Å; T118-N121 PolarHBondContact O-N 2.88Å; N121-R124 PolarHBondContact O-N 3.44Å; N121-Q125 PolarHBondContact ND2-NE2 2.82Å; N121-Q125 WeakPolarHBondContact O-CG 3.33Å; N121-Q125 PolarHBondContact O-N 2.96Å; N121-L346 HydrophobicContact CB-CD2 4.04Å; N121-L346 HydrophobicContact CB-CG 4.36Å
122I92.9Very high92.9Very high63 Ų6335.2 Ų35.232%0.32321%0.209SC..Hα-helixtrans-60.5-46.7175.9-66166.8000110.6T118 G119 R124 Q125 E126T118-I122 HydrophobicContact CG2-CD1 4.18Å; T118-I122 WeakPolarHBondContact O-CG1 3.3Å; T118-I122 PolarHBondContact O-N 3.44Å; T118-I122 VanDerWaalsContact O-N 3.08Å; G119-I122 PolarHBondContact O-N 2.86Å; I122-R124 VanDerWaalsContact C-N 3.29Å; I122-R124 PolarHBondContact O-N 3.11Å; I122-Q125 PolarHBondContact O-N 2.64Å; I122-E126 HydrophobicContact CG2-CG 4.28Å; I122-E126 WeakPolarHBondContact O-CG 3.32Å; I122-E126 PolarHBondContact O-N 3.04Å
123L93.9Very high92.8Very high0 Ų039.6 Ų39.60%023%0.228CC..Hα-helixtrans-57.2-42.7178.8-176.270000111.9M53 F87 R93 V97 L100 G119 L120 E126 W127 L151M53-L123 HydrophobicContact SD-CD2 4.32Å; F87-L123 HydrophobicContact CE2-CD1 4.14Å; F87-L123 HydrophobicContact CE2-CD2 4.42Å; F87-L123 HydrophobicContact CZ-CB 4.06Å; F87-L123 HydrophobicContact CZ-CD1 3.85Å; F87-L123 HydrophobicContact CZ-CD2 3.99Å; F87-L123 HydrophobicContact CZ-CG 4.17Å; R93-L123 HydrophobicContact CB-CD1 4.16Å; V97-L123 HydrophobicContact CG2-CD1 3.8Å; L100-L123 HydrophobicContact CD1-CD2 4.38Å; G119-L123 PolarHBondContact O-N 3.28Å; L120-L123 PolarHBondContact O-N 2.96Å; L123-E126 PolarHBondContact O-N 2.86Å; L123-W127 PolarHBondContact O-N 3.37Å; L123-L151 HydrophobicContact CD2-CD2 4.34Å; L123-L151 HydrophobicContact CG-CD2 4.46Å
124R91.3Very high92.7Very high54 Ų5439.2 Ų39.220%0.20422%0.224CC..Hα-helixtrans-65.2-44.9176.8174.3174.2171.7-91.76112.1L120 N121 I122 E126 W127 L151 I153 N329 P331L120-R124 PolarHBondContact O-N 3.45Å; L120-R124 VanDerWaalsContact O-N 3.11Å; N121-R124 PolarHBondContact O-N 3.44Å; I122-R124 VanDerWaalsContact C-N 3.29Å; I122-R124 PolarHBondContact O-N 3.11Å; R124-E126 VanDerWaalsContact C-N 3.28Å; R124-E126 PolarHBondContact O-N 2.74Å; R124-W127 VanDerWaalsContact O-CB 3.22Å; R124-W127 WeakPolarHBondContact O-CB 3.42Å; R124-W127 PolarHBondContact O-N 3.08Å; R124-L151 HydrophobicContact CB-CD2 4.35Å; R124-I153 HydrophobicContact CB-CD1 3.76Å; R124-I153 HydrophobicContact CB-CG1 4.5Å; R124-I153 HydrophobicContact CB-CG2 4.28Å; R124-I153 HydrophobicContact CG-CD1 4.29Å; R124-N329 PolarHBondContact NH2-O 3.22Å; R124-P331 VanDerWaalsContact NH1-CG 3.28Å
125Q90Very high92.8Very high123 Ų12341.2 Ų41.258%0.57523%0.234SC*.Hα-helixtrans-61.6-38.5178.9-71.7174.5-10.500111.9N121 I122N121-Q125 PolarHBondContact ND2-NE2 2.82Å; N121-Q125 WeakPolarHBondContact O-CG 3.33Å; N121-Q125 PolarHBondContact O-N 2.96Å; I122-Q125 PolarHBondContact O-N 2.64Å
126E93.1Very high92.9Very high61 Ų6144.1 Ų44.129%0.28524%0.236SC..Hα-helixtrans-85.1-5.2179.9-63.2-17917400113.8R93 I122 L123 R124 A128 G129 H130R93-E126 IonicContact CZ-OE1 2.75Å; R93-E126 IonicContact CZ-OE2 2.78Å; R93-E126 IonicContact NE-OE1 3.81Å; R93-E126 IonicContact NE-OE2 2.78Å; R93-E126 PolarHBondContact NE-OE2 3.44Å; R93-E126 IonicContact NH2-OE1 3.16Å; R93-E126 PolarHBondContact NH2-OE1 3.45Å; R93-E126 IonicContact NH2-OE2 3.1Å; R93-E126 PolarHBondContact NH2-OE2 3.01Å; R93-E126 VanDerWaalsContact NH2-OE2 3.09Å; I122-E126 HydrophobicContact CG2-CG 4.28Å; I122-E126 WeakPolarHBondContact O-CG 3.32Å; I122-E126 PolarHBondContact O-N 3.04Å; L123-E126 PolarHBondContact O-N 2.86Å; R124-E126 VanDerWaalsContact C-N 3.28Å; R124-E126 PolarHBondContact O-N 2.74Å; E126-A128 PolarHBondContact O-N 3.18Å; E126-G129 WeakPolarHBondContact O-CA 2.88Å; E126-G129 PolarHBondContact O-N 3.23Å; E126-H130 WeakPolarHBondContact CB-NE2 3.28Å; E126-H130 PolarHBondContact O-CD2 3.18Å; E126-H130 PolarHBondContact O-N 2.97Å; E126-H130 IonicContact OE2-CD2 3.14Å; E126-H130 IonicContact OE2-CE1 3.42Å; E126-H130 IonicContact OE2-NE2 2.72Å; E126-H130 PolarHBondContact OE2-NE2 3.38Å
127W92.1Very high92.9Very high13 Ų1348.1 Ų48.15%0.04926%0.256CS..Hα-helixtrans-52.1-52-169.6-178.1-103000113.4V97 L100 V101 L123 R124 G129 H130 L131 L151V97-W127 HydrophobicContact CB-CE3 4.32Å; V97-W127 HydrophobicContact CB-CZ3 3.99Å; V97-W127 HydrophobicContact CG1-CD2 4.39Å; V97-W127 HydrophobicContact CG1-CE3 3.94Å; V97-W127 HydrophobicContact CG1-CH2 3.91Å; V97-W127 HydrophobicContact CG1-CZ2 4.34Å; V97-W127 HydrophobicContact CG1-CZ3 3.71Å; V97-W127 HydrophobicContact CG2-CE3 3.63Å; V97-W127 HydrophobicContact CG2-CZ3 3.65Å; L100-W127 HydrophobicContact CB-CH2 4.09Å; L100-W127 HydrophobicContact CD1-CH2 4.24Å; L100-W127 HydrophobicContact CD1-CZ3 3.87Å; V101-W127 HydrophobicContact CG2-CH2 4.11Å; V101-W127 HydrophobicContact CG2-CZ2 4.02Å; L123-W127 PolarHBondContact O-N 3.37Å; R124-W127 VanDerWaalsContact O-CB 3.22Å; R124-W127 WeakPolarHBondContact O-CB 3.42Å; R124-W127 PolarHBondContact O-N 3.08Å; W127-G129 VanDerWaalsContact C-N 3.28Å; W127-G129 PolarHBondContact O-N 3.36Å; W127-H130 PolarHBondContact O-N 3.37Å; W127-L131 HydrophobicContact CG-CD1 4.45Å; W127-L131 HydrophobicContact CZ2-CD2 4.41Å; W127-L131 VanDerWaalsContact NE1-CD1 3.25Å; W127-L131 WeakPolarHBondContact O-CG 3.39Å; W127-L131 PolarHBondContact O-N 2.78Å; W127-L151 HydrophobicContact CB-CB 4.49Å; W127-L151 HydrophobicContact CD2-CB 3.52Å; W127-L151 HydrophobicContact CD2-CD2 4.14Å; W127-L151 HydrophobicContact CD2-CG 4.34Å; W127-L151 HydrophobicContact CE3-CB 3.86Å; W127-L151 HydrophobicContact CE3-CD1 4.46Å; W127-L151 HydrophobicContact CE3-CD2 3.6Å; W127-L151 HydrophobicContact CE3-CG 4.17Å; W127-L151 HydrophobicContact CG-CB 3.8Å; W127-L151 HydrophobicContact CH2-CB 4.43Å; W127-L151 HydrophobicContact CH2-CD1 4.16Å; W127-L151 HydrophobicContact CZ2-CB 4.15Å; W127-L151 HydrophobicContact CZ3-CB 4.28Å; W127-L151 HydrophobicContact CZ3-CD1 4.11Å; W127-L151 HydrophobicContact CZ3-CD2 3.9Å; W127-L151 HydrophobicContact CZ3-CG 4.31Å
128A90.3Very high92.7Very high73 Ų7357.3 Ų57.360%0.60330%0.296SS*.Hα-helixtrans-62.5-36.2-179.400000112.4E126 K132E126-A128 PolarHBondContact O-N 3.18Å; A128-K132 WeakPolarHBondContact O-CB 3.37Å; A128-K132 PolarHBondContact O-N 2.77Å; A128-K132 VanDerWaalsContact O-N 3.07Å
129G92.7Very high92.7Very high48 Ų4861.1 Ų61.150%0.49531%0.306SS..Hα-helixtrans-64.6-45.3175.800000112E126 W127 K132 K133E126-G129 WeakPolarHBondContact O-CA 2.88Å; E126-G129 PolarHBondContact O-N 3.23Å; W127-G129 VanDerWaalsContact C-N 3.28Å; W127-G129 PolarHBondContact O-N 3.36Å; G129-K132 PolarHBondContact O-N 2.94Å; G129-K133 PolarHBondContact O-N 2.82Å
130H94.3Very high92.6Very high10 Ų1060.8 Ų60.85%0.04630%0.301CS..Hα-helixtrans-62.9-44.5176.6-70.8-56.1000112.3V97 E126 W127 K133 L134V97-H130 HydrophobicContact CB-CB 4.11Å; V97-H130 HydrophobicContact CG1-CB 4.07Å; V97-H130 HydrophobicContact CG2-CB 3.79Å; E126-H130 WeakPolarHBondContact CB-NE2 3.28Å; E126-H130 PolarHBondContact O-CD2 3.18Å; E126-H130 PolarHBondContact O-N 2.97Å; E126-H130 IonicContact OE2-CD2 3.14Å; E126-H130 IonicContact OE2-CE1 3.42Å; E126-H130 IonicContact OE2-NE2 2.72Å; E126-H130 PolarHBondContact OE2-NE2 3.38Å; W127-H130 PolarHBondContact O-N 3.37Å; H130-K133 PolarHBondContact O-N 3.34Å; H130-L134 WeakPolarHBondContact O-CB 3.35Å; H130-L134 WeakPolarHBondContact O-CG 3.34Å; H130-L134 PolarHBondContact O-N 2.87Å
131L92.6Very high92.3Very high18 Ų1867.5 Ų67.59%0.09433%0.332CS..Hα-helixtrans-59-49176.9-73178.3000111.9V97 V101 W127 K133 L134 I135 L140 V145V97-L131 HydrophobicContact CG1-CD2 3.88Å; V97-L131 HydrophobicContact CG1-CG 4.35Å; V101-L131 HydrophobicContact CG2-CD2 3.77Å; W127-L131 HydrophobicContact CG-CD1 4.45Å; W127-L131 HydrophobicContact CZ2-CD2 4.41Å; W127-L131 VanDerWaalsContact NE1-CD1 3.25Å; W127-L131 WeakPolarHBondContact O-CG 3.39Å; W127-L131 PolarHBondContact O-N 2.78Å; L131-K133 PolarHBondContact O-N 3.15Å; L131-L134 PolarHBondContact O-N 3.07Å; L131-I135 VanDerWaalsContact O-CG1 3.32Å; L131-I135 WeakPolarHBondContact O-CG1 3.44Å; L131-I135 PolarHBondContact O-N 3.33Å; L131-L140 HydrophobicContact CD2-CD1 4.19Å; L131-V145 HydrophobicContact CB-CG1 4.25Å; L131-V145 HydrophobicContact CD1-CG1 3.65Å; L131-V145 HydrophobicContact CD2-CG1 3.9Å; L131-V145 HydrophobicContact CD2-CG2 4.07Å; L131-V145 HydrophobicContact CG-CG1 4.16Å
132K92.4Very high92Very high140 Ų14073.3 Ų73.361%0.60936%0.357SS*.Hα-helixtrans-56-44.4177-175-179.7177.2-176.60110.6A128 G129 I135 E136A128-K132 WeakPolarHBondContact O-CB 3.37Å; A128-K132 PolarHBondContact O-N 2.77Å; A128-K132 VanDerWaalsContact O-N 3.07Å; G129-K132 PolarHBondContact O-N 2.94Å; K132-I135 PolarHBondContact O-N 3.34Å; K132-E136 WeakPolarHBondContact CE-OE1 3.35Å; K132-E136 WeakPolarHBondContact O-CG 3.4Å; K132-E136 PolarHBondContact O-N 2.95Å
133K93.9Very high91.5Very high92 Ų9273.4 Ų73.440%0.437%0.367SS..Hα-helixtrans-67.6-39.8-179.6-166.564.1-174.3170.20113.1G129 H130 L131 I135 E136 L137G129-K133 PolarHBondContact O-N 2.82Å; H130-K133 PolarHBondContact O-N 3.34Å; L131-K133 PolarHBondContact O-N 3.15Å; K133-I135 VanDerWaalsContact C-N 3.33Å; K133-E136 WeakPolarHBondContact CD-OE2 3.46Å; K133-E136 IonicContact NZ-OE2 3.02Å; K133-E136 PolarHBondContact NZ-OE2 3.22Å; K133-E136 PolarHBondContact O-N 3Å; K133-L137 HydrophobicContact CG-CD1 4.28Å; K133-L137 WeakPolarHBondContact O-CB 3.48Å; K133-L137 VanDerWaalsContact O-CG 3.29Å; K133-L137 WeakPolarHBondContact O-CG 3.36Å; K133-L137 PolarHBondContact O-N 3.32Å
134L93.8Very high90.9Very high0 Ų076.7 Ų76.70%038%0.383CS..Hα-helixtrans-65.6-36.1177.3-75164.7000112.5Q94 V97 E98 H130 L131 L137 K138 R139 L140Q94-L134 HydrophobicContact CG-CD1 4.07Å; Q94-L134 HydrophobicContact CG-CD2 3.7Å; Q94-L134 HydrophobicContact CG-CG 3.63Å; V97-L134 HydrophobicContact CB-CD1 4.11Å; V97-L134 HydrophobicContact CG1-CD1 3.78Å; E98-L134 HydrophobicContact CB-CD1 3.92Å; E98-L134 HydrophobicContact CB-CD2 3.95Å; E98-L134 HydrophobicContact CG-CD2 4.29Å; H130-L134 WeakPolarHBondContact O-CB 3.35Å; H130-L134 WeakPolarHBondContact O-CG 3.34Å; H130-L134 PolarHBondContact O-N 2.87Å; L131-L134 PolarHBondContact O-N 3.07Å; L134-L137 PolarHBondContact O-N 3.27Å; L134-K138 PolarHBondContact O-N 3.29Å; L134-R139 HydrophobicContact CD2-CB 3.91Å; L134-R139 PolarHBondContact O-N 3.32Å; L134-L140 HydrophobicContact CB-CB 4.25Å; L134-L140 HydrophobicContact CB-CD1 3.71Å; L134-L140 HydrophobicContact CB-CG 3.98Å; L134-L140 HydrophobicContact CD1-CD1 3.59Å; L134-L140 HydrophobicContact CD1-CG 4.4Å; L134-L140 HydrophobicContact CG-CD1 4.21Å; L134-L140 PolarHBondContact O-N 3.23Å
135I92.8Very high90.5Very high52 Ų5274.8 Ų74.827%0.26738%0.377SS..Hα-helixtrans-67-45.8173.1-65.6164.9000110.4L131 K132 K133 L137 K138 L140 K142 V145L131-I135 VanDerWaalsContact O-CG1 3.32Å; L131-I135 WeakPolarHBondContact O-CG1 3.44Å; L131-I135 PolarHBondContact O-N 3.33Å; K132-I135 PolarHBondContact O-N 3.34Å; K133-I135 VanDerWaalsContact C-N 3.33Å; I135-L137 VanDerWaalsContact C-N 3.26Å; I135-L137 PolarHBondContact O-N 3.49Å; I135-K138 PolarHBondContact O-N 2.84Å; I135-L140 HydrophobicContact CG1-CB 4.48Å; I135-K142 HydrophobicContact CD1-CB 4.46Å; I135-K142 HydrophobicContact CD1-CG 4.42Å; I135-K142 HydrophobicContact CG2-CB 4.4Å; I135-V145 HydrophobicContact CD1-CB 4.21Å; I135-V145 HydrophobicContact CD1-CG1 4.31Å; I135-V145 HydrophobicContact CD1-CG2 4.08Å; I135-V145 HydrophobicContact CG1-CG2 4.24Å
136E93.4Very high90.1Very high106 Ų10674 Ų7450%0.49538%0.377SS..Hα-helixtrans-57.5-40.3175.6-75.6173.4-168.800112.1K132 K133 K138K132-E136 WeakPolarHBondContact CE-OE1 3.35Å; K132-E136 WeakPolarHBondContact O-CG 3.4Å; K132-E136 PolarHBondContact O-N 2.95Å; K133-E136 WeakPolarHBondContact CD-OE2 3.46Å; K133-E136 IonicContact NZ-OE2 3.02Å; K133-E136 PolarHBondContact NZ-OE2 3.22Å; K133-E136 PolarHBondContact O-N 3Å; E136-K138 PolarHBondContact O-N 2.88Å
137L93.3Very high89.3Confident93 Ų9376.1 Ų76.149%0.48739%0.389SS..THydrogen-bonded Turntrans-781.8177-66.2177.5000113.7K133 L134 I135 R139K133-L137 HydrophobicContact CG-CD1 4.28Å; K133-L137 WeakPolarHBondContact O-CB 3.48Å; K133-L137 VanDerWaalsContact O-CG 3.29Å; K133-L137 WeakPolarHBondContact O-CG 3.36Å; K133-L137 PolarHBondContact O-N 3.32Å; L134-L137 PolarHBondContact O-N 3.27Å; I135-L137 VanDerWaalsContact C-N 3.26Å; I135-L137 PolarHBondContact O-N 3.49Å; L137-R139 HydrophobicContact CB-CG 4.05Å; L137-R139 PolarHBondContact O-N 3.45Å
138K92Very high88.4Confident193 Ų19377 Ų7784%0.83940%0.395SS*.THydrogen-bonded Turntrans55.427.9-176.1-55.3-178.1178.8-179.50114L134 I135 E136L134-K138 PolarHBondContact O-N 3.29Å; I135-K138 PolarHBondContact O-N 2.84Å; E136-K138 PolarHBondContact O-N 2.88Å
139R91.9Very high87.6Confident119 Ų11975.5 Ų75.545%0.44939%0.387SS..SBendtrans-86.1-25.2174.3-64.3-168.970.9176.16.5112.1E98 L134 L137E98-R139 VanDerWaalsContact CD-NE 3.3Å; E98-R139 IonicContact OE1-CZ 2.97Å; E98-R139 IonicContact OE1-NE 3.52Å; E98-R139 PolarHBondContact OE1-NE 2.94Å; E98-R139 IonicContact OE1-NH2 2.57Å; E98-R139 PolarHBondContact OE1-NH2 2.69Å; E98-R139 IonicContact OE2-CZ 3.43Å; E98-R139 IonicContact OE2-NE 2.64Å; E98-R139 PolarHBondContact OE2-NE 2.96Å; E98-R139 IonicContact OE2-NH1 2.75Å; E98-R139 PolarHBondContact OE2-NH1 3.41Å; E98-R139 IonicContact OE2-NH2 3.06Å; E98-R139 PolarHBondContact OE2-NH2 2.94Å; L134-R139 HydrophobicContact CD2-CB 3.91Å; L134-R139 PolarHBondContact O-N 3.32Å; L137-R139 HydrophobicContact CB-CG 4.05Å; L137-R139 PolarHBondContact O-N 3.45Å
140L90.8Very high87.1Confident8 Ų878.8 Ų78.84%0.04239%0.389CS..SBendtrans-129.2144.5174.1-68.3177.5000110.4E98 V101 I102 L131 L134 I135 V145E98-L140 HydrophobicContact CG-CD2 4.28Å; E98-L140 HydrophobicContact CG-CG 4.49Å; V101-L140 HydrophobicContact CB-CD1 3.98Å; V101-L140 HydrophobicContact CB-CD2 4.12Å; V101-L140 HydrophobicContact CG1-CD1 3.76Å; V101-L140 HydrophobicContact CG1-CD2 3.6Å; V101-L140 HydrophobicContact CG1-CG 4.29Å; V101-L140 HydrophobicContact CG2-CD1 4.1Å; I102-L140 HydrophobicContact CG1-CD2 4.5Å; L131-L140 HydrophobicContact CD2-CD1 4.19Å; L134-L140 HydrophobicContact CB-CB 4.25Å; L134-L140 HydrophobicContact CB-CD1 3.71Å; L134-L140 HydrophobicContact CB-CG 3.98Å; L134-L140 HydrophobicContact CD1-CD1 3.59Å; L134-L140 HydrophobicContact CD1-CG 4.4Å; L134-L140 HydrophobicContact CG-CD1 4.21Å; L134-L140 PolarHBondContact O-N 3.23Å; I135-L140 HydrophobicContact CG1-CB 4.48Å; L140-V145 HydrophobicContact CB-CG2 4.12Å; L140-V145 HydrophobicContact CD1-CG2 4.12Å
141E88.1Confident86.9Confident141 Ų14178.5 Ų78.566%0.65939%0.388SS*.  trans-84.5138.6172.2-66.9-171.4174.600111A143 Q144 V145E141-A143 PolarHBondContact O-N 3.28Å; E141-Q144 HydrophobicContact CB-CB 4.41Å; E141-Q144 WeakPolarHBondContact O-CB 3.41Å; E141-Q144 PolarHBondContact O-N 3.12Å; E141-Q144 VanDerWaalsContact O-N 3.08Å; E141-V145 PolarHBondContact O-N 3.49Å
142K85.8Confident86.8Confident132 Ų13279 Ų7957%0.57439%0.389SS*.Hα-helixtrans-57.5-39.1178.2-170.6-179.4175.9-176.50112I135 Q144 V145 D146I135-K142 HydrophobicContact CD1-CB 4.46Å; I135-K142 HydrophobicContact CD1-CG 4.42Å; I135-K142 HydrophobicContact CG2-CB 4.4Å; K142-Q144 VanDerWaalsContact C-N 3.31Å; K142-Q144 PolarHBondContact O-N 3.26Å; K142-V145 PolarHBondContact O-N 2.84Å; K142-D146 WeakPolarHBondContact CE-OD2 3.47Å; K142-D146 WeakPolarHBondContact CG-OD2 3.07Å; K142-D146 WeakPolarHBondContact O-CB 3.42Å; K142-D146 VanDerWaalsContact O-CG 3.22Å; K142-D146 PolarHBondContact O-N 3.36Å
143A83.6Confident86.9Confident66 Ų6672.6 Ų72.655%0.54536%0.361SS..Hα-helixtrans-61-37.517800000112.8E141 L147E141-A143 PolarHBondContact O-N 3.28Å; A143-L147 WeakPolarHBondContact O-CB 3.29Å; A143-L147 PolarHBondContact O-N 2.74Å
144Q81Confident87Confident68 Ų6868.3 Ų68.332%0.31834%0.343SS..Hα-helixtrans-67.3-44.4176.4-178.6179.5-300111.1V101 E141 K142 L147 L148V101-Q144 HydrophobicContact CG1-CG 4.16Å; V101-Q144 PolarHBondContact O-NE2 3.1Å; V101-Q144 VanDerWaalsContact O-NE2 3.08Å; E141-Q144 HydrophobicContact CB-CB 4.41Å; E141-Q144 WeakPolarHBondContact O-CB 3.41Å; E141-Q144 PolarHBondContact O-N 3.12Å; E141-Q144 VanDerWaalsContact O-N 3.08Å; K142-Q144 VanDerWaalsContact C-N 3.31Å; K142-Q144 PolarHBondContact O-N 3.26Å; Q144-L147 WeakPolarHBondContact O-CB 3.47Å; Q144-L147 PolarHBondContact O-N 3Å; Q144-L148 HydrophobicContact CG-CD1 3.91Å; Q144-L148 WeakPolarHBondContact O-CD1 3.5Å; Q144-L148 WeakPolarHBondContact O-CG 3.41Å; Q144-L148 PolarHBondContact O-N 3.34Å
145V83.2Confident87.2Confident14 Ų1468.3 Ų68.39%0.08534%0.343CS..Hα-helixtrans-67.5-45.6-179.6176.60000111.7V101 L131 I135 L140 E141 K142 L147 L148 G149V101-V145 HydrophobicContact CG1-CG2 4.45Å; L131-V145 HydrophobicContact CB-CG1 4.25Å; L131-V145 HydrophobicContact CD1-CG1 3.65Å; L131-V145 HydrophobicContact CD2-CG1 3.9Å; L131-V145 HydrophobicContact CD2-CG2 4.07Å; L131-V145 HydrophobicContact CG-CG1 4.16Å; I135-V145 HydrophobicContact CD1-CB 4.21Å; I135-V145 HydrophobicContact CD1-CG1 4.31Å; I135-V145 HydrophobicContact CD1-CG2 4.08Å; I135-V145 HydrophobicContact CG1-CG2 4.24Å; L140-V145 HydrophobicContact CB-CG2 4.12Å; L140-V145 HydrophobicContact CD1-CG2 4.12Å; E141-V145 PolarHBondContact O-N 3.49Å; K142-V145 PolarHBondContact O-N 2.84Å; V145-L147 PolarHBondContact O-N 2.93Å; V145-L148 PolarHBondContact O-N 2.9Å; V145-G149 PolarHBondContact O-N 3.34Å
146D81.8Confident87.4Confident108 Ų10865.9 Ų65.958%0.57833%0.33SS*.Hα-helixtrans-60.6-30.3177.6-70.2-13.4000111K142K142-D146 WeakPolarHBondContact CE-OD2 3.47Å; K142-D146 WeakPolarHBondContact CG-OD2 3.07Å; K142-D146 WeakPolarHBondContact O-CB 3.42Å; K142-D146 VanDerWaalsContact O-CG 3.22Å; K142-D146 PolarHBondContact O-N 3.36Å
147L76.3Confident87.6Confident104 Ų10461 Ų6155%0.54531%0.307SS..Hα-helixtrans-69.5-35.5172.8-124.380.4000112.2R9 A143 Q144 V145R9-L147 VanDerWaalsContact CZ-CG 3.45Å; R9-L147 PolarHBondContact NH1-O 2.92Å; R9-L147 VanDerWaalsContact NH2-C 3.33Å; R9-L147 PolarHBondContact NH2-O 3.43Å; A143-L147 WeakPolarHBondContact O-CB 3.29Å; A143-L147 PolarHBondContact O-N 2.74Å; Q144-L147 WeakPolarHBondContact O-CB 3.47Å; Q144-L147 PolarHBondContact O-N 3Å; V145-L147 PolarHBondContact O-N 2.93Å
148L72Confident87.7Confident31 Ų3156.5 Ų56.516%0.16228%0.284CS..Hα-helixtrans-86.3-20.5-168.1-79.3158.6000113.5V101 G104 T106 Q144 V145V101-L148 HydrophobicContact CB-CD1 4.41Å; V101-L148 HydrophobicContact CG1-CD1 3.66Å; V101-L148 WeakPolarHBondContact O-CD1 3.32Å; G104-L148 VanDerWaalsContact C-CD2 3.49Å; G104-L148 VanDerWaalsContact O-CD2 3.29Å; G104-L148 WeakPolarHBondContact O-CD2 3.4Å; T106-L148 HydrophobicContact CG2-CB 3.85Å; T106-L148 HydrophobicContact CG2-CD2 3.5Å; T106-L148 VanDerWaalsContact CG2-CD2 3.5Å; T106-L148 HydrophobicContact CG2-CG 4.31Å; T106-L148 WeakPolarHBondContact CG2-O 3.42Å; Q144-L148 HydrophobicContact CG-CD1 3.91Å; Q144-L148 WeakPolarHBondContact O-CD1 3.5Å; Q144-L148 WeakPolarHBondContact O-CG 3.41Å; Q144-L148 PolarHBondContact O-N 3.34Å; V145-L148 PolarHBondContact O-N 2.9Å
149G73Confident87.9Confident42 Ų4247.6 Ų47.643%0.43325%0.246SC..  trans64.5-158.1-18000000112.5V145V145-G149 PolarHBondContact O-N 3.34Å
150E82.6Confident88.1Confident118 Ų11842 Ų4255%0.55123%0.225SC*.PPolyproline II helixtrans-90.2153.2-172.4-71.5-171.3-169.700113.9R152 A325E150-R152 PolarHBondContact O-N 2.9Å; E150-A325 HydrophobicContact CB-CB 3.74Å; E150-A325 WeakPolarHBondContact OE2-CB 3.14Å; E150-A325 VanDerWaalsContact OE2-O 3.1Å
151L89.7Confident88.3Confident3 Ų341.7 Ų41.72%0.01622%0.223CC..PPolyproline II helixtrans-72.1118.4175.4-175.771.6000111.1L108 L123 R124 W127 I153L108-L151 HydrophobicContact CB-CD1 4.11Å; L123-L151 HydrophobicContact CD2-CD2 4.34Å; L123-L151 HydrophobicContact CG-CD2 4.46Å; R124-L151 HydrophobicContact CB-CD2 4.35Å; W127-L151 HydrophobicContact CB-CB 4.49Å; W127-L151 HydrophobicContact CD2-CB 3.52Å; W127-L151 HydrophobicContact CD2-CD2 4.14Å; W127-L151 HydrophobicContact CD2-CG 4.34Å; W127-L151 HydrophobicContact CE3-CB 3.86Å; W127-L151 HydrophobicContact CE3-CD1 4.46Å; W127-L151 HydrophobicContact CE3-CD2 3.6Å; W127-L151 HydrophobicContact CE3-CG 4.17Å; W127-L151 HydrophobicContact CG-CB 3.8Å; W127-L151 HydrophobicContact CH2-CB 4.43Å; W127-L151 HydrophobicContact CH2-CD1 4.16Å; W127-L151 HydrophobicContact CZ2-CB 4.15Å; W127-L151 HydrophobicContact CZ3-CB 4.28Å; W127-L151 HydrophobicContact CZ3-CD1 4.11Å; W127-L151 HydrophobicContact CZ3-CD2 3.9Å; W127-L151 HydrophobicContact CZ3-CG 4.31Å; L151-I153 HydrophobicContact CD1-CG2 4.48Å; L151-I153 HydrophobicContact CD2-CG2 3.73Å; L151-I153 HydrophobicContact CG-CG2 3.75Å
152R91.4Very high88.7Confident29 Ų2935.6 Ų35.611%0.10920%0.195CC..EExtended strand (participates in β ladder)trans-99.7132170.2-69.7171-76144.710.7108.6T106 D107 L108 E150 L319 A325T106-R152 PolarHBondContact O-N 3.48Å; T106-R152 PolarHBondContact OG1-NH2 3.02Å; D107-R152 VanDerWaalsContact OD1-CB 3.28Å; D107-R152 WeakPolarHBondContact OD1-CB 3.46Å; D107-R152 IonicContact OD1-CZ 2.84Å; D107-R152 IonicContact OD1-NE 3.23Å; D107-R152 PolarHBondContact OD1-NE 3.44Å; D107-R152 VanDerWaalsContact OD1-NE 3.12Å; D107-R152 IonicContact OD1-NH1 2.87Å; D107-R152 PolarHBondContact OD1-NH1 2.91Å; D107-R152 IonicContact OD1-NH2 3.34Å; D107-R152 PolarHBondContact OD1-NH2 3.03Å; D107-R152 IonicContact OD2-CZ 3.5Å; D107-R152 IonicContact OD2-NH1 3.42Å; D107-R152 PolarHBondContact OD2-NH1 3.43Å; D107-R152 VanDerWaalsContact OD2-NH1 3.14Å; D107-R152 IonicContact OD2-NH2 2.82Å; D107-R152 PolarHBondContact OD2-NH2 3.15Å; L108-R152 PolarHBondContact N-O 3.46Å; E150-R152 PolarHBondContact O-N 2.9Å; R152-L319 HydrophobicContact CB-CD2 3.87Å; R152-L319 PolarHBondContact NH1-O 3.38Å; R152-A325 HydrophobicContact CG-CB 4.27Å
153I94.3Very high89Confident6 Ų629.6 Ų29.63%0.03117%0.17CC..EExtended strand (participates in β ladder)trans-126.9144.7-176.869.6177.7000111.1L108 L120 R124 L151 P331 L346L108-I153 HydrophobicContact CB-CG2 4.38Å; L108-I153 CarbonylContact O-C 3.53Å; L108-I153 VanDerWaalsContact O-CA 3.31Å; L108-I153 WeakPolarHBondContact O-CA 3.28Å; L120-I153 HydrophobicContact CD1-CB 4.32Å; L120-I153 HydrophobicContact CD1-CG2 4.06Å; L120-I153 HydrophobicContact CD2-CB 3.93Å; L120-I153 HydrophobicContact CD2-CD1 3.97Å; L120-I153 HydrophobicContact CD2-CG1 4.28Å; L120-I153 HydrophobicContact CG-CB 4.06Å; L120-I153 HydrophobicContact CG-CD1 3.76Å; L120-I153 HydrophobicContact CG-CG1 4.41Å; L120-I153 HydrophobicContact CG-CG2 4.17Å; R124-I153 HydrophobicContact CB-CD1 3.76Å; R124-I153 HydrophobicContact CB-CG1 4.5Å; R124-I153 HydrophobicContact CB-CG2 4.28Å; R124-I153 HydrophobicContact CG-CD1 4.29Å; L151-I153 HydrophobicContact CD1-CG2 4.48Å; L151-I153 HydrophobicContact CD2-CG2 3.73Å; L151-I153 HydrophobicContact CG-CG2 3.75Å; I153-P331 HydrophobicContact CD1-CB 3.63Å; I153-P331 HydrophobicContact CD1-CG 4.43Å; I153-P331 HydrophobicContact CG1-CB 3.51Å; I153-L346 HydrophobicContact CD1-CD2 3.78Å
154V96.2Very high89.4Confident2 Ų226.7 Ų26.71%0.01215%0.145CC..EExtended strand (participates in β ladder)trans-131.1133.4165.41770000110L108 V109 C110 A315 A318 L319 V332 I334L108-V154 PolarHBondContact O-N 2.9Å; V109-V154 WeakPolarHBondContact CA-O 3.29Å; C110-V154 PolarHBondContact N-O 2.8Å; V154-A315 HydrophobicContact CB-CB 4.34Å; V154-A315 HydrophobicContact CG1-CB 3.64Å; V154-A318 HydrophobicContact CG2-CB 4.09Å; V154-L319 HydrophobicContact CB-CG 4.4Å; V154-L319 HydrophobicContact CG2-CD1 4.31Å; V154-L319 HydrophobicContact CG2-CD2 3.66Å; V154-L319 HydrophobicContact CG2-CG 3.6Å; V154-V332 WeakPolarHBondContact CA-O 3.31Å; V154-V332 HydrophobicContact CG1-CG2 4.27Å; V154-V332 HydrophobicContact CG2-CG2 3.74Å; V154-I334 HydrophobicContact CG1-CD1 3.93Å; V154-I334 HydrophobicContact CG1-CG1 3.76Å
155G97.2Very high89.9Confident0 Ų023.8 Ų23.80%013%0.132CC..EExtended strand (participates in β ladder)trans-96.9137.5174.700000112.8L117 V332 V333 I334L117-G155 VanDerWaalsContact CD2-CA 3.48Å; G155-V332 PolarHBondContact N-O 2.7Å; G155-V333 VanDerWaalsContact O-CA 3.31Å; G155-V333 WeakPolarHBondContact O-CA 3.26Å; G155-V333 WeakPolarHBondContact O-CG2 3.42Å; G155-I334 PolarHBondContact O-N 3.1Å
156L98.2Very high90.2Very high0 Ų024.1 Ų24.10%014%0.138CC..EExtended strand (participates in β ladder)trans-120.2125.4165.9-61.6-173.3000108.8A28 V32 V109 C110 I111 G112 G158 M311 A315 I334A28-L156 HydrophobicContact CB-CD1 4.04Å; V32-L156 HydrophobicContact CG2-CD1 4.25Å; V109-L156 HydrophobicContact CG1-CD1 4.15Å; V109-L156 HydrophobicContact CG1-CG 4.25Å; C110-L156 PolarHBondContact O-N 3.25Å; I111-L156 WeakPolarHBondContact CA-O 3.36Å; I111-L156 HydrophobicContact CG1-CB 4.15Å; I111-L156 HydrophobicContact CG1-CD1 4.04Å; I111-L156 HydrophobicContact CG1-CG 4.5Å; I111-L156 HydrophobicContact CG2-CB 4.5Å; G112-L156 PolarHBondContact N-O 2.88Å; L156-G158 PolarHBondContact O-N 3.43Å; L156-M311 HydrophobicContact CD2-CB 3.87Å; L156-A315 HydrophobicContact CD1-CB 4.25Å; L156-A315 HydrophobicContact CD2-CB 4.06Å; L156-A315 HydrophobicContact CG-CB 4.34Å; L156-I334 HydrophobicContact CD2-CB 3.59Å; L156-I334 HydrophobicContact CD2-CG1 3.55Å
157V97Very high90.7Very high3 Ų319.8 Ų19.82%0.01812%0.116CC..EExtended strand (participates in β ladder)trans-85.899.9-174.9-1620000110.6G112 L117 F164 T170 I171 V333G112-V157 CarbonylContact O-C 3.6Å; G112-V157 WeakPolarHBondContact O-CA 3.36Å; L117-V157 HydrophobicContact CD1-CB 4.35Å; L117-V157 HydrophobicContact CD1-CG1 4.46Å; L117-V157 HydrophobicContact CD1-CG2 3.69Å; V157-F164 HydrophobicContact CG1-CB 3.69Å; V157-F164 HydrophobicContact CG1-CD1 4.27Å; V157-F164 HydrophobicContact CG1-CG 3.92Å; V157-F164 HydrophobicContact CG2-CB 4.48Å; V157-F164 HydrophobicContact CG2-CD1 3.52Å; V157-F164 HydrophobicContact CG2-CE1 3.81Å; V157-F164 HydrophobicContact CG2-CG 3.99Å; V157-T170 HydrophobicContact CB-CG2 3.82Å; V157-T170 HydrophobicContact CG1-CG2 3.34Å; V157-I171 PolarHBondContact O-N 2.92Å; V157-V333 HydrophobicContact CG2-CG2 3.63Å
158G96.4Very high91.4Very high0 Ų017 Ų170%010%0.101CC..BIsolated β-bridgetrans-100.699.7172.400000110.9M25 G112 G113 L156M25-G158 WeakPolarHBondContact CE-O 3.47Å; G112-G158 CarbonylContact C-O 3.6Å; G112-G158 VanDerWaalsContact C-O 3.29Å; G112-G158 PolarHBondContact O-N 2.94Å; G113-G158 PolarHBondContact N-O 2.78Å; L156-G158 PolarHBondContact O-N 3.43Å
159S95.6Very high92.4Very high6 Ų616.4 Ų16.44%0.04210%0.098CC..  trans-158.2144.7-179.8-177.40000109.9D161 T170 I171 V173S159-D161 PolarHBondContact OG-N 2.85Å; S159-T170 WeakPolarHBondContact O-CB 3.42Å; S159-T170 PolarHBondContact O-OG1 3.43Å; S159-I171 CarbonylContact C-O 3.56Å; S159-I171 PolarHBondContact N-O 3.24Å; S159-V173 WeakPolarHBondContact O-CG2 3.49Å
160I96.8Very high93.5Very high1 Ų114.4 Ų14.41%0.0058%0.077CC..SBendtrans-84.1-18.3171.566.5164.2000112.3A22 N162 A176 M203 L210 Q295 R296A22-I160 HydrophobicContact CB-CG2 4.18Å; I160-N162 VanDerWaalsContact C-N 3.29Å; I160-N162 PolarHBondContact O-N 2.84Å; I160-A176 HydrophobicContact CB-CB 3.82Å; I160-A176 HydrophobicContact CG2-CB 3.91Å; I160-M203 HydrophobicContact CD1-CB 4.03Å; I160-M203 HydrophobicContact CD1-SD 4.09Å; I160-L210 HydrophobicContact CB-CD1 4.47Å; I160-L210 HydrophobicContact CD1-CD1 4.35Å; I160-L210 HydrophobicContact CG1-CD1 4.44Å; I160-L210 WeakPolarHBondContact O-CD1 3.37Å; I160-L210 WeakPolarHBondContact O-CG 3.37Å; I160-Q295 HydrophobicContact CD1-CB 4.36Å; I160-R296 HydrophobicContact CD1-CG 3.73Å
161D94.9Very high94.2Very high1 Ų18.8 Ų8.81%0.0055%0.051CC..SBendtrans-76.9-19.9-167.7-57.1-36.3000112.2S159 D163 G204 R205 C207 R296S159-D161 PolarHBondContact OG-N 2.85Å; D161-D163 HydrophobicContact CB-CB 4.18Å; D161-D163 PolarHBondContact O-N 3.33Å; D161-G204 VanDerWaalsContact OD1-CA 3.29Å; D161-G204 WeakPolarHBondContact OD1-CA 3.38Å; D161-R205 IonicContact OD2-CZ 2.69Å; D161-R205 IonicContact OD2-NE 2.68Å; D161-C207 WeakPolarHBondContact O-CB 3.37Å; D161-R296 IonicContact OD2-NH2 3.04Å
162N94.9Very high94.6Very high13 Ų138.7 Ų8.77%0.075%0.05CC..  trans51.538.3-171.4-153.532.5000113.4I160 D168 M169 T170 V173 Y209I160-N162 VanDerWaalsContact C-N 3.29Å; I160-N162 PolarHBondContact O-N 2.84Å; N162-D168 PolarHBondContact ND2-O 2.98Å; N162-M169 VanDerWaalsContact OD1-CA 3.26Å; N162-M169 WeakPolarHBondContact OD1-CA 3.41Å; N162-T170 PolarHBondContact OD1-N 3.42Å; N162-V173 HydrophobicContact CB-CG1 4.37Å; N162-V173 HydrophobicContact CB-CG2 3.66Å; N162-Y209 HydrophobicContact CB-CD1 3.75Å; N162-Y209 HydrophobicContact CB-CD2 4.41Å; N162-Y209 HydrophobicContact CB-CE1 4.29Å; N162-Y209 HydrophobicContact CB-CG 3.83Å; N162-Y209 WeakPolarHBondContact ND2-CD2 3.38Å; N162-Y209 WeakPolarHBondContact ND2-CE2 3.45Å; N162-Y209 VanDerWaalsContact ND2-CZ 3.29Å
163D92.2Very high94.9Very high7 Ų77.3 Ų7.34%0.0375%0.045CC..  trans-96.7-1.4-171.466.4-18.9000114.5D161 R205 C207 R372D161-D163 HydrophobicContact CB-CB 4.18Å; D161-D163 PolarHBondContact O-N 3.33Å; D163-R205 IonicContact OD2-NH1 3.43Å; D163-R205 PolarHBondContact OD2-NH1 3.32Å; D163-R205 VanDerWaalsContact OD2-NH1 3.11Å; D163-C207 HydrophobicContact CB-CB 3.92Å; D163-R372 VanDerWaalsContact CA-NH1 3.31Å; D163-R372 PolarHBondContact O-NH1 3.12Å
164F92.7Very high95Very high5 Ų57 Ų72%0.0224%0.044CC..  trans-88.7123.8179.8-166.7-97.7000111.6D114 L117 V157 T170 V333 L346 C349 V350D114-F164 HydrophobicContact CB-CD2 4Å; L117-F164 HydrophobicContact CB-CE2 4.29Å; L117-F164 HydrophobicContact CD1-CD2 4.43Å; L117-F164 HydrophobicContact CD1-CE1 4.42Å; L117-F164 HydrophobicContact CD1-CE2 3.9Å; L117-F164 HydrophobicContact CD1-CZ 3.89Å; V157-F164 HydrophobicContact CG1-CB 3.69Å; V157-F164 HydrophobicContact CG1-CD1 4.27Å; V157-F164 HydrophobicContact CG1-CG 3.92Å; V157-F164 HydrophobicContact CG2-CB 4.48Å; V157-F164 HydrophobicContact CG2-CD1 3.52Å; V157-F164 HydrophobicContact CG2-CE1 3.81Å; V157-F164 HydrophobicContact CG2-CG 3.99Å; F164-T170 HydrophobicContact CB-CG2 4.3Å; F164-V333 HydrophobicContact CE1-CG1 4.16Å; F164-V333 HydrophobicContact CE1-CG2 4.02Å; F164-V333 HydrophobicContact CZ-CG2 4.44Å; F164-L346 HydrophobicContact CZ-CD1 4.2Å; F164-C349 HydrophobicContact CD1-CB 4.42Å; F164-C349 HydrophobicContact CE1-CB 3.47Å; F164-C349 VanDerWaalsContact CE1-CB 3.47Å; F164-C349 HydrophobicContact CZ-CB 3.58Å; F164-V350 HydrophobicContact CE2-CG2 4.1Å; F164-V350 HydrophobicContact CZ-CG2 4.32Å
165C92Very high95.1Very high7 Ų77.2 Ų7.25%0.0475%0.045CC..THydrogen-bonded Turntrans-71.6148.9-179.2-65.30000111.9C349 Q352 T353C165-C349 WeakPolarHBondContact O-CB 3.3Å; C165-Q352 HydrophobicContact CB-CB 3.66Å; C165-T353 PolarHBondContact N-OG1 3.23Å
166G89.2Confident95.2Very high21 Ų217.2 Ų7.222%0.2165%0.045CC..THydrogen-bonded Turntrans92.7-1.217800000115.4T335 R344G166-T335 VanDerWaalsContact O-CB 3.29Å; G166-T335 WeakPolarHBondContact O-CB 3.23Å; G166-T335 PolarHBondContact O-OG1 3.17Å; G166-R344 WeakPolarHBondContact O-CD 3.28Å; G166-R344 PolarHBondContact O-NE 3.39Å; G166-R344 VanDerWaalsContact O-NE 3.1Å
167T92.7Very high95.2Very high17 Ų177.4 Ų7.410%0.1045%0.046CC..  trans-126.1141.1170.6-164.10000110.6M169 T170 L336T167-M169 VanDerWaalsContact C-N 3.34Å; T167-M169 PolarHBondContact OG1-O 3.43Å; T167-T170 HydrophobicContact CG2-CG2 3.54Å; T167-L336 WeakPolarHBondContact CA-O 3.27Å; T167-L336 PolarHBondContact OG1-N 3.07Å
168D90.3Very high95.2Very high46 Ų468.7 Ų8.725%0.2465%0.053CC..SBendtrans-71.1-33.2174.3-82.9-43.2000112.1N162 L336 D337 G338 T375N162-D168 PolarHBondContact ND2-O 2.98Å; D168-L336 PolarHBondContact N-O 3.45Å; D168-D337 WeakPolarHBondContact OD2-CA 3.09Å; D168-G338 PolarHBondContact OD2-N 3.38Å; D168-T375 PolarHBondContact OD1-OG1 2.9Å
169M93.6Very high95.3Very high17 Ų1711.7 Ų11.78%0.0846%0.064CC..SBendtrans-150.5132.9-178.1-162.7170.6-67.500110.6N162 T167 V173 D174 F303 L336N162-M169 VanDerWaalsContact OD1-CA 3.26Å; N162-M169 WeakPolarHBondContact OD1-CA 3.41Å; T167-M169 VanDerWaalsContact C-N 3.34Å; T167-M169 PolarHBondContact OG1-O 3.43Å; M169-V173 HydrophobicContact CG-CB 3.7Å; M169-V173 HydrophobicContact CG-CG1 3.91Å; M169-V173 HydrophobicContact CG-CG2 4.24Å; M169-V173 HydrophobicContact SD-CB 4.33Å; M169-V173 HydrophobicContact SD-CG1 4.31Å; M169-D174 HydrophobicContact SD-CB 4.11Å; M169-F303 HydrophobicContact CG-CE1 4.26Å; M169-F303 HydrophobicContact SD-CD1 4.01Å; M169-F303 HydrophobicContact SD-CE1 3.34Å; M169-F303 WeakPolarHBondContact SD-CE1 3.29Å; M169-F303 HydrophobicContact SD-CZ 3.87Å; M169-L336 HydrophobicContact CB-CD2 4.13Å
170T95.8Very high95.4Very high1 Ų111.4 Ų11.41%0.0066%0.062CC..  trans-90.2157.2173.153.80000111.7V157 S159 N162 F164 T167 G172 V173V157-T170 HydrophobicContact CB-CG2 3.82Å; V157-T170 HydrophobicContact CG1-CG2 3.34Å; S159-T170 WeakPolarHBondContact O-CB 3.42Å; S159-T170 PolarHBondContact O-OG1 3.43Å; N162-T170 PolarHBondContact OD1-N 3.42Å; F164-T170 HydrophobicContact CB-CG2 4.3Å; T167-T170 HydrophobicContact CG2-CG2 3.54Å; T170-G172 PolarHBondContact O-N 3.22Å; T170-V173 WeakPolarHBondContact O-CG2 3.44Å; T170-V173 PolarHBondContact O-N 2.85Å; T170-V173 WeakPolarHBondContact OG1-CG2 3.39Å
171I97.7Very high95.4Very high0 Ų011.5 Ų11.50%06%0.063CC..BIsolated β-bridgetrans-62.8121.3176.6-60.6165.2000108.8A22 A28 V157 S159 L307 A308 M311A22-I171 WeakPolarHBondContact CB-O 3.37Å; A28-I171 HydrophobicContact CB-CD1 4.25Å; V157-I171 PolarHBondContact O-N 2.92Å; S159-I171 CarbonylContact C-O 3.56Å; S159-I171 PolarHBondContact N-O 3.24Å; I171-L307 HydrophobicContact CG1-CD2 4.17Å; I171-L307 HydrophobicContact CG1-CG 4.31Å; I171-A308 HydrophobicContact CD1-CB 3.92Å; I171-A308 HydrophobicContact CG1-CB 4.16Å; I171-A308 HydrophobicContact CG2-CB 3.91Å; I171-M311 HydrophobicContact CD1-SD 3.81Å; I171-M311 HydrophobicContact CG1-SD 3.83Å
172G97.1Very high95.4Very high0 Ų016.4 Ų16.40%09%0.086CC..THydrogen-bonded Turntrans108.2-11.4176.800000114.7A23 T170 A176 D304A23-G172 WeakPolarHBondContact O-CA 3.49Å; A23-G172 PolarHBondContact O-N 2.79Å; T170-G172 PolarHBondContact O-N 3.22Å; G172-A176 WeakPolarHBondContact O-CB 3.4Å; G172-A176 PolarHBondContact O-N 3.08Å; G172-D304 WeakPolarHBondContact CA-OD2 3.1Å; G172-D304 PolarHBondContact N-OD1 3.4Å; G172-D304 PolarHBondContact N-OD2 3.42Å
173V97.4Very high95.5Very high0 Ų017.2 Ų17.20%09%0.093CC..Hα-helixtrans-64.5-47.7179.9173.40000111.1S159 N162 M169 T170 S175 A176 L177 Y209 L210S159-V173 WeakPolarHBondContact O-CG2 3.49Å; N162-V173 HydrophobicContact CB-CG1 4.37Å; N162-V173 HydrophobicContact CB-CG2 3.66Å; M169-V173 HydrophobicContact CG-CB 3.7Å; M169-V173 HydrophobicContact CG-CG1 3.91Å; M169-V173 HydrophobicContact CG-CG2 4.24Å; M169-V173 HydrophobicContact SD-CB 4.33Å; M169-V173 HydrophobicContact SD-CG1 4.31Å; T170-V173 WeakPolarHBondContact O-CG2 3.44Å; T170-V173 PolarHBondContact O-N 2.85Å; T170-V173 WeakPolarHBondContact OG1-CG2 3.39Å; V173-S175 VanDerWaalsContact C-N 3.32Å; V173-S175 PolarHBondContact O-N 3.22Å; V173-A176 PolarHBondContact O-N 2.9Å; V173-L177 HydrophobicContact CG1-CD1 4.07Å; V173-L177 WeakPolarHBondContact O-CG 3.25Å; V173-L177 PolarHBondContact O-N 3.43Å; V173-Y209 HydrophobicContact CG1-CD1 3.93Å; V173-Y209 HydrophobicContact CG1-CE1 3.53Å; V173-L210 HydrophobicContact CG1-CD2 4.18Å
174D97.6Very high95.6Very high1 Ų117 Ų171%0.0059%0.092CC..Hα-helixtrans-65.1-39.4-178.4-176.473.4000111.1M169 L177 N178 S301 F303 D304M169-D174 HydrophobicContact SD-CB 4.11Å; D174-L177 PolarHBondContact O-N 3.46Å; D174-N178 PolarHBondContact O-N 3.46Å; D174-N178 PolarHBondContact O-ND2 3.05Å; D174-N178 PolarHBondContact OD2-ND2 3.3Å; D174-N178 VanDerWaalsContact OD2-ND2 3.15Å; D174-S301 WeakPolarHBondContact OD2-CB 3.24Å; D174-S301 PolarHBondContact OD2-OG 3.45Å; D174-F303 HydrophobicContact CB-CB 4.19Å; D174-F303 HydrophobicContact CB-CD1 3.72Å; D174-F303 HydrophobicContact CB-CG 4.23Å; D174-D304 PolarHBondContact N-OD2 2.94Å
175S98.2Very high95.7Very high5 Ų518 Ų184%0.03510%0.097CC..Hα-helixtrans-62.4-45.4174-60.10000111.8A23 V173 L177 N178 R179 P300 S301 D304A23-S175 VanDerWaalsContact CB-CB 3.45Å; V173-S175 VanDerWaalsContact C-N 3.32Å; V173-S175 PolarHBondContact O-N 3.22Å; S175-L177 VanDerWaalsContact C-N 3.33Å; S175-L177 PolarHBondContact O-N 3.42Å; S175-N178 WeakPolarHBondContact O-CB 3.29Å; S175-N178 PolarHBondContact O-N 3.14Å; S175-N178 VanDerWaalsContact O-N 3.17Å; S175-R179 WeakPolarHBondContact O-CG 3.27Å; S175-R179 PolarHBondContact O-N 3.34Å; S175-R179 VanDerWaalsContact O-N 3.09Å; S175-P300 WeakPolarHBondContact OG-CA 3.36Å; S175-S301 PolarHBondContact OG-N 3.38Å; S175-D304 WeakPolarHBondContact CB-OD2 3.41Å; S175-D304 PolarHBondContact N-OD2 2.67Å; S175-D304 PolarHBondContact OG-OD2 2.68Å
176A98.1Very high95.7Very high1 Ų120.4 Ų20.41%0.00812%0.117CC..Hα-helixtrans-60.6-43.6175.700000111.3I160 G172 V173 N178 R179 I180 L210 Q295I160-A176 HydrophobicContact CB-CB 3.82Å; I160-A176 HydrophobicContact CG2-CB 3.91Å; G172-A176 WeakPolarHBondContact O-CB 3.4Å; G172-A176 PolarHBondContact O-N 3.08Å; V173-A176 PolarHBondContact O-N 2.9Å; A176-N178 VanDerWaalsContact C-N 3.32Å; A176-N178 PolarHBondContact O-N 2.69Å; A176-R179 WeakPolarHBondContact O-CB 3.21Å; A176-R179 PolarHBondContact O-N 2.91Å; A176-R179 VanDerWaalsContact O-N 3.12Å; A176-I180 WeakPolarHBondContact O-CD1 3.08Å; A176-I180 VanDerWaalsContact O-CG1 3.27Å; A176-I180 WeakPolarHBondContact O-CG1 3.06Å; A176-I180 PolarHBondContact O-N 3.39Å; A176-L210 HydrophobicContact CB-CD1 4.36Å; A176-L210 HydrophobicContact CB-CD2 4.1Å; A176-Q295 WeakPolarHBondContact CA-O 3.35Å; A176-Q295 WeakPolarHBondContact CB-O 3.49Å
177L98.1Very high95.9Very high4 Ų420.3 Ų20.32%0.02111%0.112CC..Hα-helixtrans-60.3-39.8174.3-72.3171.8000112.2V173 D174 S175 R179 I180 V181 Y209 L210 I213 P673V173-L177 HydrophobicContact CG1-CD1 4.07Å; V173-L177 WeakPolarHBondContact O-CG 3.25Å; V173-L177 PolarHBondContact O-N 3.43Å; D174-L177 PolarHBondContact O-N 3.46Å; S175-L177 VanDerWaalsContact C-N 3.33Å; S175-L177 PolarHBondContact O-N 3.42Å; L177-R179 VanDerWaalsContact C-N 3.31Å; L177-R179 PolarHBondContact O-N 3.17Å; L177-I180 HydrophobicContact CD2-CD1 4.35Å; L177-I180 PolarHBondContact O-N 3.35Å; L177-V181 WeakPolarHBondContact O-CB 3.29Å; L177-V181 VanDerWaalsContact O-CG2 3.3Å; L177-V181 WeakPolarHBondContact O-CG2 2.94Å; L177-V181 PolarHBondContact O-N 2.94Å; L177-Y209 HydrophobicContact CD1-CE1 4.47Å; L177-L210 HydrophobicContact CD2-CD2 3.75Å; L177-L210 HydrophobicContact CG-CD2 3.77Å; L177-I213 HydrophobicContact CD1-CB 4.18Å; L177-I213 HydrophobicContact CD1-CG2 3.71Å; L177-I213 HydrophobicContact CD2-CB 3.86Å; L177-I213 HydrophobicContact CD2-CG2 3.9Å; L177-I213 HydrophobicContact CG-CG2 4.46Å; L177-P673 HydrophobicContact CB-CB 3.98Å; L177-P673 HydrophobicContact CB-CG 4.11Å
178N97.8Very high95.7Very high30 Ų3020.2 Ų20.216%0.1611%0.113CC..Hα-helixtrans-60.5-41.1174.8-85.4-88.5000111.3D174 S175 A176 E182 P673D174-N178 PolarHBondContact O-N 3.46Å; D174-N178 PolarHBondContact O-ND2 3.05Å; D174-N178 PolarHBondContact OD2-ND2 3.3Å; D174-N178 VanDerWaalsContact OD2-ND2 3.15Å; S175-N178 WeakPolarHBondContact O-CB 3.29Å; S175-N178 PolarHBondContact O-N 3.14Å; S175-N178 VanDerWaalsContact O-N 3.17Å; A176-N178 VanDerWaalsContact C-N 3.32Å; A176-N178 PolarHBondContact O-N 2.69Å; N178-E182 VanDerWaalsContact O-CB 3.29Å; N178-E182 WeakPolarHBondContact O-CB 3.35Å; N178-E182 PolarHBondContact O-N 2.82Å; N178-P673 HydrophobicContact CB-CG 4.35Å; N178-P673 VanDerWaalsContact OD1-CD 3.22Å; N178-P673 WeakPolarHBondContact OD1-CD 3.5Å
179R97.7Very high95.6Very high63 Ų6321.3 Ų21.324%0.23813%0.125CC..Hα-helixtrans-67.1-41.8176.3-60.7-62.692.9-150.3-6.1112.3S175 A176 L177 E182 S183 V294S175-R179 WeakPolarHBondContact O-CG 3.27Å; S175-R179 PolarHBondContact O-N 3.34Å; S175-R179 VanDerWaalsContact O-N 3.09Å; A176-R179 WeakPolarHBondContact O-CB 3.21Å; A176-R179 PolarHBondContact O-N 2.91Å; A176-R179 VanDerWaalsContact O-N 3.12Å; L177-R179 VanDerWaalsContact C-N 3.31Å; L177-R179 PolarHBondContact O-N 3.17Å; R179-E182 IonicContact CZ-OE2 3.73Å; R179-E182 VanDerWaalsContact NH1-CD 3.33Å; R179-E182 IonicContact NH1-OE1 3.24Å; R179-E182 PolarHBondContact NH1-OE1 3.2Å; R179-E182 IonicContact NH1-OE2 2.8Å; R179-E182 PolarHBondContact NH1-OE2 3.37Å; R179-E182 IonicContact NH2-OE2 2.71Å; R179-E182 PolarHBondContact NH2-OE2 3.11Å; R179-S183 WeakPolarHBondContact O-CB 3.48Å; R179-S183 PolarHBondContact O-N 3.08Å; R179-S183 VanDerWaalsContact O-N 3.09Å; R179-S183 PolarHBondContact O-OG 3.32Å; R179-V294 VanDerWaalsContact CG-O 3.28Å; R179-V294 WeakPolarHBondContact CG-O 3.46Å
180I98Very high95.4Very high0 Ų023.2 Ų23.20%014%0.137CC..Hα-helixtrans-62.7-51.4178-65.9158.1000109.9A176 L177 E182 S183 I184 V202 L210 A214 L291 Q295A176-I180 WeakPolarHBondContact O-CD1 3.08Å; A176-I180 VanDerWaalsContact O-CG1 3.27Å; A176-I180 WeakPolarHBondContact O-CG1 3.06Å; A176-I180 PolarHBondContact O-N 3.39Å; L177-I180 HydrophobicContact CD2-CD1 4.35Å; L177-I180 PolarHBondContact O-N 3.35Å; I180-E182 PolarHBondContact O-N 2.89Å; I180-S183 WeakPolarHBondContact O-CB 3.44Å; I180-S183 PolarHBondContact O-N 3.26Å; I180-S183 VanDerWaalsContact O-N 3.16Å; I180-I184 HydrophobicContact CG2-CD1 3.6Å; I180-I184 HydrophobicContact CG2-CG1 4.31Å; I180-I184 VanDerWaalsContact O-CG1 3.29Å; I180-I184 WeakPolarHBondContact O-CG1 3.09Å; I180-I184 PolarHBondContact O-N 2.92Å; I180-V202 HydrophobicContact CD1-CG1 3.48Å; I180-V202 VanDerWaalsContact CD1-CG1 3.48Å; I180-V202 HydrophobicContact CG1-CG1 4.07Å; I180-V202 HydrophobicContact CG2-CG2 4.04Å; I180-L210 HydrophobicContact CD1-CB 3.96Å; I180-L210 HydrophobicContact CD1-CD1 4.2Å; I180-L210 HydrophobicContact CD1-CD2 4.1Å; I180-L210 HydrophobicContact CD1-CG 4.32Å; I180-A214 HydrophobicContact CG2-CB 3.6Å; I180-L291 HydrophobicContact CB-CD1 4.24Å; I180-L291 HydrophobicContact CG1-CD1 4.01Å; I180-L291 HydrophobicContact CG2-CD1 4.16Å; I180-Q295 HydrophobicContact CG1-CG 3.89Å
181V96.9Very high95.1Very high3 Ų323.1 Ų23.12%0.01814%0.137CC..Hα-helixtrans-65.7-40.1-177.8172.60000111.8L177 S183 I184 D185 V217 P673 R676L177-V181 WeakPolarHBondContact O-CB 3.29Å; L177-V181 VanDerWaalsContact O-CG2 3.3Å; L177-V181 WeakPolarHBondContact O-CG2 2.94Å; L177-V181 PolarHBondContact O-N 2.94Å; V181-S183 VanDerWaalsContact C-N 3.28Å; V181-S183 PolarHBondContact O-N 3.35Å; V181-I184 PolarHBondContact O-N 2.94Å; V181-D185 WeakPolarHBondContact O-CB 3.5Å; V181-D185 PolarHBondContact O-N 2.86Å; V181-V217 HydrophobicContact CG2-CG2 3.46Å; V181-V217 VanDerWaalsContact CG2-CG2 3.46Å; V181-P673 HydrophobicContact CB-CG 4.06Å; V181-P673 HydrophobicContact CG2-CB 4.16Å; V181-P673 HydrophobicContact CG2-CG 3.86Å; V181-R676 VanDerWaalsContact CG1-NH1 3.29Å
182E95.5Very high94.5Very high103 Ų10326.9 Ų26.948%0.48115%0.154SC..Hα-helixtrans-58.3-43.5173-178.8179.5144.300111.5N178 R179 I180 D185 A186N178-E182 VanDerWaalsContact O-CB 3.29Å; N178-E182 WeakPolarHBondContact O-CB 3.35Å; N178-E182 PolarHBondContact O-N 2.82Å; R179-E182 IonicContact CZ-OE2 3.73Å; R179-E182 VanDerWaalsContact NH1-CD 3.33Å; R179-E182 IonicContact NH1-OE1 3.24Å; R179-E182 PolarHBondContact NH1-OE1 3.2Å; R179-E182 IonicContact NH1-OE2 2.8Å; R179-E182 PolarHBondContact NH1-OE2 3.37Å; R179-E182 IonicContact NH2-OE2 2.71Å; R179-E182 PolarHBondContact NH2-OE2 3.11Å; I180-E182 PolarHBondContact O-N 2.89Å; E182-D185 PolarHBondContact O-N 3.39Å; E182-A186 WeakPolarHBondContact O-CB 3.46Å; E182-A186 PolarHBondContact O-N 3.23Å
183S96.1Very high94.1Very high31 Ų3130.9 Ų30.922%0.21718%0.182CC..Hα-helixtrans-66.5-42179-55.60000111.9R179 I180 V181 A186 V187 L291R179-S183 WeakPolarHBondContact O-CB 3.48Å; R179-S183 PolarHBondContact O-N 3.08Å; R179-S183 VanDerWaalsContact O-N 3.09Å; R179-S183 PolarHBondContact O-OG 3.32Å; I180-S183 WeakPolarHBondContact O-CB 3.44Å; I180-S183 PolarHBondContact O-N 3.26Å; I180-S183 VanDerWaalsContact O-N 3.16Å; V181-S183 VanDerWaalsContact C-N 3.28Å; V181-S183 PolarHBondContact O-N 3.35Å; S183-A186 PolarHBondContact O-N 2.71Å; S183-V187 WeakPolarHBondContact O-CB 3.45Å; S183-V187 VanDerWaalsContact O-CG2 3.3Å; S183-V187 WeakPolarHBondContact O-CG2 3.25Å; S183-V187 PolarHBondContact O-N 2.93Å; S183-L291 VanDerWaalsContact CB-CD2 3.43Å
184I96Very high93.6Very high3 Ų336 Ų362%0.01521%0.206CC..Hα-helixtrans-64.5-46.3176.2-63.5165.6000110.5I180 V181 A186 V187 A188 I200 A214 I254 I256I180-I184 HydrophobicContact CG2-CD1 3.6Å; I180-I184 HydrophobicContact CG2-CG1 4.31Å; I180-I184 VanDerWaalsContact O-CG1 3.29Å; I180-I184 WeakPolarHBondContact O-CG1 3.09Å; I180-I184 PolarHBondContact O-N 2.92Å; V181-I184 PolarHBondContact O-N 2.94Å; I184-A186 VanDerWaalsContact C-N 3.28Å; I184-A186 PolarHBondContact O-N 2.85Å; I184-V187 PolarHBondContact O-N 3.33Å; I184-A188 VanDerWaalsContact O-CB 3.3Å; I184-A188 WeakPolarHBondContact O-CB 3.42Å; I184-A188 PolarHBondContact O-N 3.28Å; I184-I200 HydrophobicContact CB-CD1 4.26Å; I184-I200 HydrophobicContact CG1-CD1 3.65Å; I184-I200 HydrophobicContact CG1-CG2 4.44Å; I184-I200 HydrophobicContact CG2-CD1 4.28Å; I184-A214 HydrophobicContact CD1-CB 4.22Å; I184-I254 HydrophobicContact CG2-CG2 4.23Å; I184-I256 HydrophobicContact CD1-CD1 3.75Å
185D93.5Very high93.1Very high24 Ų2440.9 Ų40.913%0.12823%0.229CC..Hα-helixtrans-60.2-39.8178.3-76.8-7.1000110.9V181 E182 A188 S189 N670 R676V181-D185 WeakPolarHBondContact O-CB 3.5Å; V181-D185 PolarHBondContact O-N 2.86Å; E182-D185 PolarHBondContact O-N 3.39Å; D185-A188 PolarHBondContact O-N 3.23Å; D185-S189 PolarHBondContact O-N 2.96Å; D185-N670 PolarHBondContact OD2-ND2 3.01Å; D185-R676 IonicContact OD1-NH1 2.65Å; D185-R676 PolarHBondContact OD1-NH1 3.18Å; D185-R676 IonicContact OD1-NH2 3.04Å; D185-R676 IonicContact OD2-CZ 2.7Å; D185-R676 IonicContact OD2-NH1 2.98Å; D185-R676 IonicContact OD2-NH2 3.12Å; D185-R676 PolarHBondContact OD2-NH2 2.71Å
186A93Very high92.8Very high58 Ų5843.2 Ų43.248%0.47924%0.237SC..Hα-helixtrans-65.1-46.6175.600000111.9E182 S183 I184 A188 S189E182-A186 WeakPolarHBondContact O-CB 3.46Å; E182-A186 PolarHBondContact O-N 3.23Å; S183-A186 PolarHBondContact O-N 2.71Å; I184-A186 VanDerWaalsContact C-N 3.28Å; I184-A186 PolarHBondContact O-N 2.85Å; A186-A188 VanDerWaalsContact C-N 3.34Å; A186-A188 PolarHBondContact O-N 3.14Å; A186-S189 PolarHBondContact O-N 2.86Å; A186-S189 PolarHBondContact O-OG 2.99Å
187V92.7Very high92.7Very high19 Ų1943.1 Ų43.112%0.11524%0.237CC..Hα-helixtrans-64-38.8177.3166.40000111.6S183 I184 S189 T190 A191 F198 I200 I254S183-V187 WeakPolarHBondContact O-CB 3.45Å; S183-V187 VanDerWaalsContact O-CG2 3.3Å; S183-V187 WeakPolarHBondContact O-CG2 3.25Å; S183-V187 PolarHBondContact O-N 2.93Å; I184-V187 PolarHBondContact O-N 3.33Å; V187-S189 PolarHBondContact O-N 2.86Å; V187-T190 WeakPolarHBondContact O-CG2 3.31Å; V187-T190 PolarHBondContact O-N 3.2Å; V187-A191 WeakPolarHBondContact O-CB 2.94Å; V187-A191 PolarHBondContact O-N 3.03Å; V187-F198 HydrophobicContact CG1-CB 3.81Å; V187-F198 HydrophobicContact CG1-CD1 3.3Å; V187-F198 HydrophobicContact CG1-CD2 3.61Å; V187-F198 HydrophobicContact CG1-CE1 3.63Å; V187-F198 HydrophobicContact CG1-CE2 3.93Å; V187-F198 HydrophobicContact CG1-CG 3.27Å; V187-F198 HydrophobicContact CG1-CZ 3.92Å; V187-I200 HydrophobicContact CG1-CD1 4.33Å; V187-I254 HydrophobicContact CG1-CD1 4.49Å
188A89Confident92.7Very high15 Ų1543.6 Ų43.612%0.12424%0.238CC..Hα-helixtrans-59.7-34.8-178.900000112.1I184 D185 A186 A191 Q192I184-A188 VanDerWaalsContact O-CB 3.3Å; I184-A188 WeakPolarHBondContact O-CB 3.42Å; I184-A188 PolarHBondContact O-N 3.28Å; D185-A188 PolarHBondContact O-N 3.23Å; A186-A188 VanDerWaalsContact C-N 3.34Å; A186-A188 PolarHBondContact O-N 3.14Å; A188-A191 PolarHBondContact O-N 2.86Å; A188-Q192 WeakPolarHBondContact O-CB 3.48Å; A188-Q192 PolarHBondContact O-N 2.94Å
189S87.5Confident92.7Very high70 Ų7042.1 Ų42.149%0.4923%0.231SC..Hα-helixtrans-64.4-47.9179.570.50000112.2D185 A186 V187 Q192 S193D185-S189 PolarHBondContact O-N 2.96Å; A186-S189 PolarHBondContact O-N 2.86Å; A186-S189 PolarHBondContact O-OG 2.99Å; V187-S189 PolarHBondContact O-N 2.86Å; S189-Q192 PolarHBondContact O-N 3.12Å; S189-S193 PolarHBondContact O-N 3.44Å; S189-S193 PolarHBondContact O-OG 2.9Å
190T90.4Very high92.7Very high56 Ų5639.2 Ų39.234%0.34422%0.22SC..Hα-helixtrans-70.3-34175.5-1760000112.3V187 Q192 S193 H194 F198V187-T190 WeakPolarHBondContact O-CG2 3.31Å; V187-T190 PolarHBondContact O-N 3.2Å; T190-Q192 VanDerWaalsContact C-N 3.3Å; T190-Q192 PolarHBondContact O-N 3.35Å; T190-S193 PolarHBondContact O-N 3.14Å; T190-H194 PolarHBondContact O-CD2 3.31Å; T190-H194 PolarHBondContact O-N 2.73Å; T190-F198 HydrophobicContact CG2-CZ 4.09Å
191A88Confident92.7Very high0 Ų041.4 Ų41.40%023%0.23CC..Hα-helixtrans-61.9-41.2176.600000111.6V187 A188 S193 H194 Q195 R196 F198 V252V187-A191 WeakPolarHBondContact O-CB 2.94Å; V187-A191 PolarHBondContact O-N 3.03Å; A188-A191 PolarHBondContact O-N 2.86Å; A191-S193 VanDerWaalsContact C-N 3.33Å; A191-S193 PolarHBondContact O-N 2.94Å; A191-H194 PolarHBondContact O-N 3.38Å; A191-Q195 WeakPolarHBondContact O-CA 3.35Å; A191-Q195 PolarHBondContact O-N 3.42Å; A191-R196 HydrophobicContact CB-CB 4.49Å; A191-R196 PolarHBondContact O-N 3.46Å; A191-F198 HydrophobicContact CB-CD2 3.55Å; A191-F198 HydrophobicContact CB-CE2 3.45Å; A191-F198 VanDerWaalsContact CB-CE2 3.45Å; A191-V252 VanDerWaalsContact C-CG2 3.48Å; A191-V252 HydrophobicContact CB-CB 4.28Å; A191-V252 HydrophobicContact CB-CG1 3.52Å; A191-V252 HydrophobicContact CB-CG2 3.81Å
192Q86.9Confident92.8Very high78 Ų7841.3 Ų41.336%0.36423%0.23SC..Hα-helixtrans-65.4-35.9-179.5-170.1173.711.500112.4A188 S189 T190 R251 V252A188-Q192 WeakPolarHBondContact O-CB 3.48Å; A188-Q192 PolarHBondContact O-N 2.94Å; S189-Q192 PolarHBondContact O-N 3.12Å; T190-Q192 VanDerWaalsContact C-N 3.3Å; T190-Q192 PolarHBondContact O-N 3.35Å; Q192-R251 PolarHBondContact O-NE 3.36Å; Q192-R251 PolarHBondContact O-NH2 3.23Å; Q192-V252 HydrophobicContact CB-CG2 3.75Å; Q192-V252 HydrophobicContact CG-CG2 4.39Å
193S87.9Confident92.9Very high84 Ų8437.3 Ų37.359%0.58721%0.211SC*.Hα-helixtrans-64.9-44.7175.6-59.30000112.1S189 T190 A191 R251S189-S193 PolarHBondContact O-N 3.44Å; S189-S193 PolarHBondContact O-OG 2.9Å; T190-S193 PolarHBondContact O-N 3.14Å; A191-S193 VanDerWaalsContact C-N 3.33Å; A191-S193 PolarHBondContact O-N 2.94Å; S193-R251 PolarHBondContact O-NH2 2.86Å
194H86.2Confident92.8Very high107 Ų10735.8 Ų35.850%0.49520%0.2SC..Hα-helixtrans-99.84.5-172.2-67.3-68.7000115.2T190 A191 R196T190-H194 PolarHBondContact O-CD2 3.31Å; T190-H194 PolarHBondContact O-N 2.73Å; A191-H194 PolarHBondContact O-N 3.38Å; H194-R196 VanDerWaalsContact C-N 3.3Å; H194-R196 HydrophobicContact CB-CG 3.67Å; H194-R196 PolarHBondContact CD2-NH1 3.1Å; H194-R196 PolarHBondContact O-N 2.73Å
195Q87.8Confident92.6Very high104 Ų10440.8 Ų40.849%0.48622%0.219SC..THydrogen-bonded Turntrans56.241.1-174.9-57.7-171.635.100113.3A191 R246 R251A191-Q195 WeakPolarHBondContact O-CA 3.35Å; A191-Q195 PolarHBondContact O-N 3.42Å; Q195-R246 VanDerWaalsContact C-NH2 3.35Å; Q195-R246 VanDerWaalsContact O-CZ 3.31Å; Q195-R246 PolarHBondContact O-NH1 3.29Å; Q195-R246 PolarHBondContact O-NH2 3Å; Q195-R251 CarbonylContact C-O 3.52Å; Q195-R251 VanDerWaalsContact C-O 3.3Å; Q195-R251 WeakPolarHBondContact CA-O 3.49Å; Q195-R251 HydrophobicContact CG-CB 4.49Å; Q195-R251 VanDerWaalsContact CG-CZ 3.47Å; Q195-R251 VanDerWaalsContact CG-NH2 3.28Å
196R92.5Very high92.5Very high54 Ų5445.9 Ų45.920%0.20424%0.237CC..  trans-93.8160-170.2-75.9176176.8154.15.2114.3A191 H194 F198 R246 N253 D285A191-R196 HydrophobicContact CB-CB 4.49Å; A191-R196 PolarHBondContact O-N 3.46Å; H194-R196 VanDerWaalsContact C-N 3.3Å; H194-R196 HydrophobicContact CB-CG 3.67Å; H194-R196 PolarHBondContact CD2-NH1 3.1Å; H194-R196 PolarHBondContact O-N 2.73Å; R196-F198 HydrophobicContact CB-CD2 4.13Å; R196-F198 HydrophobicContact CB-CE2 3.71Å; R196-R246 VanDerWaalsContact C-NH2 3.3Å; R196-R246 PolarHBondContact O-NH2 2.77Å; R196-R246 VanDerWaalsContact O-NH2 3.16Å; R196-N253 PolarHBondContact O-N 3.24Å; R196-D285 HydrophobicContact CG-CB 4.12Å; R196-D285 IonicContact CZ-OD2 3.09Å; R196-D285 IonicContact NE-OD2 3.74Å; R196-D285 PolarHBondContact NE-OD2 3.43Å; R196-D285 IonicContact NH2-OD2 2.79Å; R196-D285 PolarHBondContact NH2-OD2 3.08Å
197T95.7Very high92.5Very high0 Ų043.1 Ų43.10%021%0.214CC..EExtended strand (participates in β ladder)trans-104.2133.7166.9-59.40000109.5N253 I255 V278 D285 T286 R287T197-N253 CarbonylContact C-O 3.4Å; T197-N253 WeakPolarHBondContact CA-O 3.27Å; T197-N253 HydrophobicContact CG2-CB 3.81Å; T197-N253 PolarHBondContact OG1-OD1 3.2Å; T197-I255 HydrophobicContact CG2-CD1 3.77Å; T197-I255 HydrophobicContact CG2-CG1 4.49Å; T197-V278 HydrophobicContact CG2-CG1 4.24Å; T197-D285 PolarHBondContact N-O 2.79Å; T197-T286 HydrophobicContact CG2-CG2 3.93Å; T197-T286 CarbonylContact O-C 3.28Å; T197-T286 VanDerWaalsContact O-CA 3.26Å; T197-T286 WeakPolarHBondContact O-CA 3.33Å; T197-R287 PolarHBondContact O-N 3.48Å
198F96.8Very high92.7Very high13 Ų1342.2 Ų42.26%0.05721%0.208CC..EExtended strand (participates in β ladder)trans-118.5132.3176-80.2-96.7000110.8V187 T190 A191 R196 I200 N253 I254 I255 R287V187-F198 HydrophobicContact CG1-CB 3.81Å; V187-F198 HydrophobicContact CG1-CD1 3.3Å; V187-F198 HydrophobicContact CG1-CD2 3.61Å; V187-F198 HydrophobicContact CG1-CE1 3.63Å; V187-F198 HydrophobicContact CG1-CE2 3.93Å; V187-F198 HydrophobicContact CG1-CG 3.27Å; V187-F198 HydrophobicContact CG1-CZ 3.92Å; T190-F198 HydrophobicContact CG2-CZ 4.09Å; A191-F198 HydrophobicContact CB-CD2 3.55Å; A191-F198 HydrophobicContact CB-CE2 3.45Å; A191-F198 VanDerWaalsContact CB-CE2 3.45Å; R196-F198 HydrophobicContact CB-CD2 4.13Å; R196-F198 HydrophobicContact CB-CE2 3.71Å; F198-I200 HydrophobicContact CB-CG1 4.3Å; F198-N253 PolarHBondContact N-O 3Å; F198-I254 HydrophobicContact CB-CD1 4.04Å; F198-I255 PolarHBondContact O-N 2.99Å; F198-R287 WeakPolarHBondContact CA-O 3.21Å; F198-R287 HydrophobicContact CD1-CB 3.86Å; F198-R287 HydrophobicContact CE1-CB 3.69Å; F198-R287 HydrophobicContact CE1-CG 4.34Å; F198-R287 HydrophobicContact CZ-CB 4.26Å; F198-R287 HydrophobicContact CZ-CG 4.49Å
199V97.8Very high93Very high0 Ų042 Ų420%020%0.204CC..EExtended strand (participates in β ladder)trans-103.2113168-1730000107.4I255 C257 V274 T286 R287 V288 T289V199-I255 CarbonylContact C-O 3.6Å; V199-I255 WeakPolarHBondContact CA-O 3.22Å; V199-I255 HydrophobicContact CG1-CG2 4.45Å; V199-I255 HydrophobicContact CG2-CB 4.37Å; V199-I255 HydrophobicContact CG2-CD1 4.18Å; V199-C257 HydrophobicContact CG1-CB 4.39Å; V199-V274 HydrophobicContact CG1-CB 4.17Å; V199-V274 HydrophobicContact CG1-CG1 4.16Å; V199-V274 HydrophobicContact CG2-CB 4.29Å; V199-V274 HydrophobicContact CG2-CG1 3.8Å; V199-T286 HydrophobicContact CG2-CG2 4.04Å; V199-R287 PolarHBondContact N-O 2.85Å; V199-V288 HydrophobicContact CB-CG2 4.2Å; V199-V288 CarbonylContact O-C 3.52Å; V199-V288 WeakPolarHBondContact O-CA 3.35Å; V199-T289 PolarHBondContact O-N 3.28Å
200I98Very high93.5Very high1 Ų138.6 Ų38.61%0.00518%0.181CC..EExtended strand (participates in β ladder)trans-107116.7-174.6-58.1178.4000108.3I184 V187 F198 V202 I254 I255 I256 C257 T289 L291I184-I200 HydrophobicContact CB-CD1 4.26Å; I184-I200 HydrophobicContact CG1-CD1 3.65Å; I184-I200 HydrophobicContact CG1-CG2 4.44Å; I184-I200 HydrophobicContact CG2-CD1 4.28Å; V187-I200 HydrophobicContact CG1-CD1 4.33Å; F198-I200 HydrophobicContact CB-CG1 4.3Å; I200-V202 HydrophobicContact CG2-CG2 4.2Å; I200-I254 HydrophobicContact CD1-CG2 3.96Å; I200-I255 PolarHBondContact N-O 3.42Å; I200-I256 WeakPolarHBondContact O-CA 3.19Å; I200-C257 PolarHBondContact O-N 3.23Å; I200-T289 WeakPolarHBondContact CA-O 3.37Å; I200-L291 HydrophobicContact CG2-CD1 3.98Å; I200-L291 HydrophobicContact CG2-CD2 4.2Å; I200-L291 HydrophobicContact CG2-CG 3.91Å
201E98.5Very high93.9Very high46 Ų4636 Ų3622%0.21516%0.164CC..EExtended strand (participates in β ladder)trans-90.4124.9178.5-167178.5116.300110.6C257 S271 T289 V290 L291E201-C257 WeakPolarHBondContact CA-O 3.43Å; E201-S271 VanDerWaalsContact OE2-CB 3.29Å; E201-S271 WeakPolarHBondContact OE2-CB 3.44Å; E201-S271 PolarHBondContact OE2-OG 3.35Å; E201-T289 PolarHBondContact N-O 3.42Å; E201-V290 HydrophobicContact CB-CB 4.38Å; E201-V290 HydrophobicContact CB-CG1 4.31Å; E201-V290 HydrophobicContact CB-CG2 4.09Å; E201-L291 PolarHBondContact O-N 3.42Å
202V98.2Very high94.3Very high2 Ų236 Ų361%0.01217%0.165CC..EExtended strand (participates in β ladder)trans-119.8141-171.7176.50000109.3I180 I200 L210 I256 C257 E259 L291I180-V202 HydrophobicContact CD1-CG1 3.48Å; I180-V202 VanDerWaalsContact CD1-CG1 3.48Å; I180-V202 HydrophobicContact CG1-CG1 4.07Å; I180-V202 HydrophobicContact CG2-CG2 4.04Å; I200-V202 HydrophobicContact CG2-CG2 4.2Å; V202-L210 HydrophobicContact CG1-CB 3.74Å; V202-I256 HydrophobicContact CB-CG2 4.29Å; V202-I256 HydrophobicContact CG2-CG2 3.7Å; V202-C257 PolarHBondContact N-O 3.32Å; V202-E259 PolarHBondContact O-N 2.87Å; V202-L291 HydrophobicContact CG2-CD1 4.3Å
203M97.8Very high94.8Very high18 Ų1832.4 Ų32.49%0.08915%0.148CC..  trans-69.5171.9177.5-74.7179.899.300111.5I160 L210 Q295 R296I160-M203 HydrophobicContact CD1-CB 4.03Å; I160-M203 HydrophobicContact CD1-SD 4.09Å; M203-L210 WeakPolarHBondContact O-CD1 3.48Å; M203-Q295 VanDerWaalsContact CG-NE2 3.33Å; M203-Q295 HydrophobicContact SD-CB 4.28Å; M203-R296 HydrophobicContact SD-CG 4.43Å
204G94Very high95.2Very high0 Ų028.4 Ų28.40%012%0.12CC..  trans150.72.6176.600000113.5D161 R206 C207 E259D161-G204 VanDerWaalsContact OD1-CA 3.29Å; D161-G204 WeakPolarHBondContact OD1-CA 3.38Å; G204-R206 PolarHBondContact O-N 3.41Å; G204-C207 CarbonylContact C-O 3.6Å; G204-C207 WeakPolarHBondContact CA-O 3.46Å; G204-C207 WeakPolarHBondContact O-CA 3.22Å; G204-C207 VanDerWaalsContact O-CB 3.31Å; G204-C207 WeakPolarHBondContact O-CB 3.39Å; G204-C207 PolarHBondContact O-N 3.06Å; G204-E259 PolarHBondContact N-OE1 2.93Å
205R91.7Very high95.7Very high108 Ų10823.4 Ų23.441%0.40810%0.097SC..THydrogen-bonded Turntrans56.3-100.2-176.7-173.6-167.7-69159.4-10.6111.5D114 D161 D163 E259 G260D114-R205 IonicContact OD1-NH1 3.52Å; D114-R205 PolarHBondContact OD1-NH1 2.91Å; D161-R205 IonicContact OD2-CZ 2.69Å; D161-R205 IonicContact OD2-NE 2.68Å; D163-R205 IonicContact OD2-NH1 3.43Å; D163-R205 PolarHBondContact OD2-NH1 3.32Å; D163-R205 VanDerWaalsContact OD2-NH1 3.11Å; R205-E259 VanDerWaalsContact CA-OE1 3.27Å; R205-E259 WeakPolarHBondContact CA-OE1 3.38Å; R205-E259 PolarHBondContact N-OE1 3.3Å; R205-G260 WeakPolarHBondContact O-CA 3.44Å; R205-G260 PolarHBondContact O-N 3.2Å
206R91.5Very high96.1Very high131 Ų13118.8 Ų18.849%0.4948%0.076SC..THydrogen-bonded Turntrans-11424.1175.8-69.9-171.6172.8-158-1.4110.9G204 D361 R372G204-R206 PolarHBondContact O-N 3.41Å; R206-D361 IonicContact CZ-OD1 3.98Å; R206-D361 IonicContact NH1-OD1 3.59Å; R206-D361 PolarHBondContact NH1-OD1 3.28Å; R206-D361 IonicContact NH1-OD2 2.76Å; R206-R372 PolarHBondContact O-NH2 3.01Å
207C94.6Very high96.2Very high0 Ų016.2 Ų16.20%07%0.066CC..  trans-122.9126.8175.7-167.50000111D161 D163 G204 Y209 E227 R372D161-C207 WeakPolarHBondContact O-CB 3.37Å; D163-C207 HydrophobicContact CB-CB 3.92Å; G204-C207 CarbonylContact C-O 3.6Å; G204-C207 WeakPolarHBondContact CA-O 3.46Å; G204-C207 WeakPolarHBondContact O-CA 3.22Å; G204-C207 VanDerWaalsContact O-CB 3.31Å; G204-C207 WeakPolarHBondContact O-CB 3.39Å; G204-C207 PolarHBondContact O-N 3.06Å; C207-Y209 VanDerWaalsContact C-N 3.28Å; C207-Y209 PolarHBondContact O-N 3.38Å; C207-E227 VanDerWaalsContact CA-OE1 3.23Å; C207-E227 WeakPolarHBondContact CA-OE1 3.43Å; C207-E227 PolarHBondContact SG-OE1 3.32Å; C207-R372 VanDerWaalsContact SG-CZ 3.56Å
208G95.5Very high96.1Very high0 Ų017.1 Ų17.10%07%0.072CC..  trans-84.15.3176.600000114.2L210 A211 L212 E227G208-L210 PolarHBondContact O-N 3.2Å; G208-A211 PolarHBondContact O-N 2.86Å; G208-L212 VanDerWaalsContact O-CB 3.28Å; G208-L212 WeakPolarHBondContact O-CB 3.39Å; G208-L212 PolarHBondContact O-N 3.05Å; G208-E227 VanDerWaalsContact CA-OE2 3.26Å; G208-E227 WeakPolarHBondContact CA-OE2 3.46Å; G208-E227 VanDerWaalsContact N-CD 3.34Å; G208-E227 PolarHBondContact N-OE1 3.41Å; G208-E227 VanDerWaalsContact N-OE1 3.12Å; G208-E227 PolarHBondContact N-OE2 2.95Å
209Y96.4Very high95.9Very high9 Ų917.8 Ų17.84%0.0358%0.075CC..Hα-helixtrans-56.2-51.7-172.8-175.3-88.8000112.2N162 V173 L177 C207 A211 L212 I213 F376N162-Y209 HydrophobicContact CB-CD1 3.75Å; N162-Y209 HydrophobicContact CB-CD2 4.41Å; N162-Y209 HydrophobicContact CB-CE1 4.29Å; N162-Y209 HydrophobicContact CB-CG 3.83Å; N162-Y209 WeakPolarHBondContact ND2-CD2 3.38Å; N162-Y209 WeakPolarHBondContact ND2-CE2 3.45Å; N162-Y209 VanDerWaalsContact ND2-CZ 3.29Å; V173-Y209 HydrophobicContact CG1-CD1 3.93Å; V173-Y209 HydrophobicContact CG1-CE1 3.53Å; L177-Y209 HydrophobicContact CD1-CE1 4.47Å; C207-Y209 VanDerWaalsContact C-N 3.28Å; C207-Y209 PolarHBondContact O-N 3.38Å; Y209-A211 PolarHBondContact O-N 2.58Å; Y209-L212 PolarHBondContact O-N 3.28Å; Y209-I213 HydrophobicContact CD1-CG1 3.98Å; Y209-I213 HydrophobicContact CD2-CG1 4.45Å; Y209-I213 HydrophobicContact CE1-CG1 3.57Å; Y209-I213 HydrophobicContact CE2-CD1 4.31Å; Y209-I213 HydrophobicContact CE2-CG1 4.14Å; Y209-I213 HydrophobicContact CG-CG1 4.4Å; Y209-I213 WeakPolarHBondContact O-CG1 3.34Å; Y209-I213 PolarHBondContact O-N 3.33Å; Y209-F376 AromaticContact CD2-CD2 3.84Å; Y209-F376 HydrophobicContact CD2-CD2 3.84Å; Y209-F376 HydrophobicContact CD2-CE2 4.18Å
210L97.8Very high95.7Very high0 Ų018 Ų180%08%0.077CC..Hα-helixtrans-59.2-46.7179.7-70.9178.5000111.7I160 V173 A176 L177 I180 V202 M203 G208 L212 A214I160-L210 HydrophobicContact CB-CD1 4.47Å; I160-L210 HydrophobicContact CD1-CD1 4.35Å; I160-L210 HydrophobicContact CG1-CD1 4.44Å; I160-L210 WeakPolarHBondContact O-CD1 3.37Å; I160-L210 WeakPolarHBondContact O-CG 3.37Å; V173-L210 HydrophobicContact CG1-CD2 4.18Å; A176-L210 HydrophobicContact CB-CD1 4.36Å; A176-L210 HydrophobicContact CB-CD2 4.1Å; L177-L210 HydrophobicContact CD2-CD2 3.75Å; L177-L210 HydrophobicContact CG-CD2 3.77Å; I180-L210 HydrophobicContact CD1-CB 3.96Å; I180-L210 HydrophobicContact CD1-CD1 4.2Å; I180-L210 HydrophobicContact CD1-CD2 4.1Å; I180-L210 HydrophobicContact CD1-CG 4.32Å; V202-L210 HydrophobicContact CG1-CB 3.74Å; M203-L210 WeakPolarHBondContact O-CD1 3.48Å; G208-L210 PolarHBondContact O-N 3.2Å; L210-L212 PolarHBondContact O-N 3.48Å; L210-A214 WeakPolarHBondContact O-CB 3.28Å; L210-A214 PolarHBondContact O-N 3.19Å
211A97.6Very high95.4Very high0 Ų018.5 Ų18.50%08%0.08CC..Hα-helixtrans-62.6-41.6178.600000112.3G208 Y209 S215 V223 T225 I256G208-A211 PolarHBondContact O-N 2.86Å; Y209-A211 PolarHBondContact O-N 2.58Å; A211-S215 WeakPolarHBondContact O-CB 3.45Å; A211-S215 PolarHBondContact O-N 3.49Å; A211-S215 PolarHBondContact O-OG 2.78Å; A211-V223 HydrophobicContact CB-CG2 3.97Å; A211-V223 WeakPolarHBondContact O-CG2 3.4Å; A211-T225 HydrophobicContact CB-CG2 4.23Å; A211-I256 HydrophobicContact CB-CG2 3.8Å
212L96.9Very high95.3Very high2 Ų217.9 Ų17.91%0.018%0.076CC..Hα-helixtrans-67.6-45.8179175.761.4000112.2G208 Y209 L210 S215 I216 T225 F376 N379 F380 Y383G208-L212 VanDerWaalsContact O-CB 3.28Å; G208-L212 WeakPolarHBondContact O-CB 3.39Å; G208-L212 PolarHBondContact O-N 3.05Å; Y209-L212 PolarHBondContact O-N 3.28Å; L210-L212 PolarHBondContact O-N 3.48Å; L212-S215 PolarHBondContact O-N 2.92Å; L212-S215 PolarHBondContact O-OG 3.19Å; L212-I216 HydrophobicContact CD1-CD1 4.37Å; L212-I216 HydrophobicContact CG-CD1 4.43Å; L212-I216 WeakPolarHBondContact O-CG1 3.28Å; L212-I216 PolarHBondContact O-N 3.32Å; L212-T225 HydrophobicContact CB-CG2 4.48Å; L212-F376 HydrophobicContact CD2-CD1 4.35Å; L212-F376 HydrophobicContact CD2-CE1 3.99Å; L212-F376 HydrophobicContact CD2-CE2 4.34Å; L212-F376 HydrophobicContact CD2-CZ 3.97Å; L212-N379 HydrophobicContact CD2-CB 3.98Å; L212-N379 HydrophobicContact CG-CB 4.35Å; L212-F380 HydrophobicContact CD2-CB 4.15Å; L212-Y383 HydrophobicContact CD1-CD1 4.42Å; L212-Y383 HydrophobicContact CD1-CG 4.1Å
213I97Very high95.2Very high1 Ų117.9 Ų17.91%0.0058%0.076CC..Hα-helixtrans-67.9-44.8177.7-60.4-51000110L177 Y209 S215 I216 V217 N379 L677L177-I213 HydrophobicContact CD1-CB 4.18Å; L177-I213 HydrophobicContact CD1-CG2 3.71Å; L177-I213 HydrophobicContact CD2-CB 3.86Å; L177-I213 HydrophobicContact CD2-CG2 3.9Å; L177-I213 HydrophobicContact CG-CG2 4.46Å; Y209-I213 HydrophobicContact CD1-CG1 3.98Å; Y209-I213 HydrophobicContact CD2-CG1 4.45Å; Y209-I213 HydrophobicContact CE1-CG1 3.57Å; Y209-I213 HydrophobicContact CE2-CD1 4.31Å; Y209-I213 HydrophobicContact CE2-CG1 4.14Å; Y209-I213 HydrophobicContact CG-CG1 4.4Å; Y209-I213 WeakPolarHBondContact O-CG1 3.34Å; Y209-I213 PolarHBondContact O-N 3.33Å; I213-S215 PolarHBondContact O-N 3.24Å; I213-I216 HydrophobicContact CD1-CD1 4.45Å; I213-I216 PolarHBondContact O-N 3.45Å; I213-I216 VanDerWaalsContact O-N 3.15Å; I213-V217 HydrophobicContact CG2-CG1 4.2Å; I213-V217 WeakPolarHBondContact O-CG2 3.44Å; I213-V217 PolarHBondContact O-N 3.1Å; I213-N379 HydrophobicContact CD1-CB 3.98Å; I213-N379 VanDerWaalsContact CD1-ND2 3.3Å; I213-N379 WeakPolarHBondContact CD1-ND2 3.46Å; I213-L677 HydrophobicContact CD1-CD1 4.26Å; I213-L677 HydrophobicContact CD1-CD2 3.94Å; I213-L677 HydrophobicContact CG2-CD2 3.98Å
214A97.5Very high95.2Very high0 Ų017.1 Ų17.10%07%0.072CC..Hα-helixtrans-55.2-41.4176.400000111.3I180 I184 L210 I216 V217 S218 I256I180-A214 HydrophobicContact CG2-CB 3.6Å; I184-A214 HydrophobicContact CD1-CB 4.22Å; L210-A214 WeakPolarHBondContact O-CB 3.28Å; L210-A214 PolarHBondContact O-N 3.19Å; A214-I216 PolarHBondContact O-N 2.88Å; A214-V217 PolarHBondContact O-N 3.02Å; A214-S218 VanDerWaalsContact O-CB 3.24Å; A214-S218 WeakPolarHBondContact O-CB 3.44Å; A214-S218 PolarHBondContact O-N 3.15Å; A214-S218 PolarHBondContact O-OG 2.72Å; A214-I256 HydrophobicContact CB-CD1 3.79Å
215S96.2Very high95.3Very high2 Ų217.3 Ų17.31%0.0147%0.073CC..Hα-helixtrans-65.7-38.6179.670.20000112.8A211 L212 I213 E219 A220 Y383A211-S215 WeakPolarHBondContact O-CB 3.45Å; A211-S215 PolarHBondContact O-N 3.49Å; A211-S215 PolarHBondContact O-OG 2.78Å; L212-S215 PolarHBondContact O-N 2.92Å; L212-S215 PolarHBondContact O-OG 3.19Å; I213-S215 PolarHBondContact O-N 3.24Å; S215-E219 PolarHBondContact O-N 3.42Å; S215-E219 VanDerWaalsContact O-N 3.12Å; S215-A220 PolarHBondContact O-N 3.05Å; S215-Y383 WeakPolarHBondContact OG-CD2 3.44Å; S215-Y383 WeakPolarHBondContact OG-CE2 3.32Å
216I95.2Very high95.4Very high8 Ų812.6 Ų12.64%0.0416%0.056CC..Hα-helixtrans-65.2-50.4176.4-63.7164.1000110.7L212 I213 A214 S218 N379 Y383 L677 T680L212-I216 HydrophobicContact CD1-CD1 4.37Å; L212-I216 HydrophobicContact CG-CD1 4.43Å; L212-I216 WeakPolarHBondContact O-CG1 3.28Å; L212-I216 PolarHBondContact O-N 3.32Å; I213-I216 HydrophobicContact CD1-CD1 4.45Å; I213-I216 PolarHBondContact O-N 3.45Å; I213-I216 VanDerWaalsContact O-N 3.15Å; A214-I216 PolarHBondContact O-N 2.88Å; I216-S218 PolarHBondContact O-N 2.8Å; I216-N379 HydrophobicContact CD1-CB 3.86Å; I216-N379 VanDerWaalsContact CD1-O 3.31Å; I216-N379 WeakPolarHBondContact CD1-O 3.12Å; I216-Y383 HydrophobicContact CG1-CD2 4.41Å; I216-L677 HydrophobicContact CD1-CD1 4.34Å; I216-L677 HydrophobicContact CG2-CD1 4.09Å; I216-T680 HydrophobicContact CG2-CG2 3.94Å
217V95.3Very high95.5Very high0 Ų06.3 Ų6.30%03%0.033CC..Hα-helixtrans-81.8-13.4-171.1-54.70000114V181 I213 A214 T463 P673 R676 L677V181-V217 HydrophobicContact CG2-CG2 3.46Å; V181-V217 VanDerWaalsContact CG2-CG2 3.46Å; I213-V217 HydrophobicContact CG2-CG1 4.2Å; I213-V217 WeakPolarHBondContact O-CG2 3.44Å; I213-V217 PolarHBondContact O-N 3.1Å; A214-V217 PolarHBondContact O-N 3.02Å; V217-T463 WeakPolarHBondContact O-CG2 3.21Å; V217-P673 HydrophobicContact CG2-CB 4.49Å; V217-R676 HydrophobicContact CB-CB 3.75Å; V217-R676 HydrophobicContact CG1-CB 3.85Å; V217-R676 VanDerWaalsContact O-CD 3.23Å; V217-R676 WeakPolarHBondContact O-CD 2.94Å; V217-R676 PolarHBondContact O-NH1 3.43Å; V217-L677 HydrophobicContact CG1-CB 3.79Å; V217-L677 HydrophobicContact CG1-CD1 4.47Å
218S93.8Very high95.4Very high19 Ų1910.4 Ų10.413%0.1335%0.048CC..Hα-helixtrans-107.5-0.3174.367.50000114.2A214 I216 A220A214-S218 VanDerWaalsContact O-CB 3.24Å; A214-S218 WeakPolarHBondContact O-CB 3.44Å; A214-S218 PolarHBondContact O-N 3.15Å; A214-S218 PolarHBondContact O-OG 2.72Å; I216-S218 PolarHBondContact O-N 2.8Å; S218-A220 VanDerWaalsContact C-N 3.33Å; S218-A220 PolarHBondContact O-N 3.11Å
219E92.3Very high95.3Very high26 Ų2610.5 Ų10.512%0.1215%0.049CC..THydrogen-bonded Turntrans59.837.7-176.5-45.1-170.6-157.500114.1S215 D221 R423 D461 W462 T463S215-E219 PolarHBondContact O-N 3.42Å; S215-E219 VanDerWaalsContact O-N 3.12Å; E219-D221 PolarHBondContact O-N 2.94Å; E219-R423 VanDerWaalsContact CD-NH2 3.26Å; E219-R423 VanDerWaalsContact CG-NH2 3.35Å; E219-R423 VanDerWaalsContact OE1-CD 3.28Å; E219-R423 WeakPolarHBondContact OE1-CD 3.24Å; E219-R423 IonicContact OE1-CZ 3.92Å; E219-R423 IonicContact OE1-NE 3.84Å; E219-R423 PolarHBondContact OE1-NE 3.33Å; E219-R423 VanDerWaalsContact OE1-NE 3.07Å; E219-R423 IonicContact OE2-CZ 3.67Å; E219-R423 IonicContact OE2-NE 3.91Å; E219-R423 PolarHBondContact OE2-NE 2.88Å; E219-R423 IonicContact OE2-NH2 3.48Å; E219-R423 PolarHBondContact OE2-NH2 3.29Å; E219-D461 WeakPolarHBondContact OE1-CA 3.29Å; E219-D461 PolarHBondContact OE1-N 3.17Å; E219-D461 PolarHBondContact OE2-N 3.17Å; E219-W462 PolarHBondContact OE1-N 3.41Å; E219-T463 VanDerWaalsContact CD-OG1 3.26Å; E219-T463 WeakPolarHBondContact CG-OG1 3.26Å; E219-T463 WeakPolarHBondContact OE1-CB 3.37Å; E219-T463 PolarHBondContact OE1-N 2.94Å; E219-T463 PolarHBondContact OE1-OG1 2.8Å
220A93.4Very high95.2Very high4 Ų410.4 Ų10.43%0.0335%0.049CC..  trans-60.6139.2-17900000112.1S215 S218 W222 I254 I256S215-A220 PolarHBondContact O-N 3.05Å; S218-A220 VanDerWaalsContact C-N 3.33Å; S218-A220 PolarHBondContact O-N 3.11Å; A220-W222 VanDerWaalsContact C-N 3.32Å; A220-W222 PolarHBondContact O-N 3.1Å; A220-I254 HydrophobicContact CB-CB 4.46Å; A220-I254 HydrophobicContact CB-CG2 4.16Å; A220-I256 HydrophobicContact CB-CD1 3.81Å; A220-I256 HydrophobicContact CB-CG1 3.9Å
221D93.2Very high95Very high13 Ų1312.2 Ų12.27%0.076%0.061CC..SBendtrans-68.7-33.2179.3-57.4-100.2000111.9E219 K241 L242 S245 N253 I254E219-D221 PolarHBondContact O-N 2.94Å; D221-K241 WeakPolarHBondContact O-CD 3.41Å; D221-K241 WeakPolarHBondContact O-CE 3.27Å; D221-K241 PolarHBondContact O-NZ 3.38Å; D221-L242 HydrophobicContact CB-CD2 3.97Å; D221-S245 PolarHBondContact OD1-OG 3.29Å; D221-N253 PolarHBondContact OD1-ND2 3.22Å; D221-N253 WeakPolarHBondContact OD2-CA 3.39Å; D221-I254 PolarHBondContact N-O 2.93Å; D221-I254 PolarHBondContact OD2-N 3.38Å
222W95.4Very high94.8Very high32 Ų3219.3 Ų19.312%0.1219%0.094CC..EExtended strand (participates in β ladder)trans-147.1150.2178.2-156.3-80000111.9A220 F224 V230 L237 L238 K241 I254 I255 I256 Y383A220-W222 VanDerWaalsContact C-N 3.32Å; A220-W222 PolarHBondContact O-N 3.1Å; W222-F224 AromaticContact CD1-CD2 3.78Å; W222-F224 AromaticContact CD1-CE2 3.46Å; W222-F224 VanDerWaalsContact CD1-CE2 3.46Å; W222-F224 AromaticContact CD1-CZ 3.7Å; W222-F224 HydrophobicContact CG-CE2 4.37Å; W222-F224 AromaticContact NE1-CE1 3.91Å; W222-F224 AromaticContact NE1-CE2 3.99Å; W222-F224 AromaticContact NE1-CZ 3.77Å; W222-V230 HydrophobicContact CZ2-CG1 4.24Å; W222-L237 HydrophobicContact CH2-CB 3.92Å; W222-L238 HydrophobicContact CB-CD1 3.68Å; W222-L238 HydrophobicContact CD2-CD1 3.76Å; W222-L238 HydrophobicContact CE3-CD1 3.88Å; W222-L238 HydrophobicContact CG-CD1 3.64Å; W222-K241 HydrophobicContact CE3-CB 4.24Å; W222-K241 HydrophobicContact CE3-CD 3.47Å; W222-K241 VanDerWaalsContact CE3-CD 3.47Å; W222-K241 HydrophobicContact CE3-CG 4.48Å; W222-K241 HydrophobicContact CZ3-CB 4.06Å; W222-K241 HydrophobicContact CZ3-CD 3.65Å; W222-K241 HydrophobicContact CZ3-CG 4.49Å; W222-I254 PolarHBondContact N-O 3.06Å; W222-I255 HydrophobicContact CB-CG1 4.3Å; W222-I255 HydrophobicContact CB-CG2 4.19Å; W222-I255 WeakPolarHBondContact O-CA 3.47Å; W222-I256 PolarHBondContact O-N 2.85Å; W222-Y383 VanDerWaalsContact C-OH 3.28Å; W222-Y383 WeakPolarHBondContact CA-OH 3.25Å
223V96.7Very high94.6Very high2 Ų223.2 Ų23.21%0.01212%0.115CC..EExtended strand (participates in β ladder)trans-133.8139.6173.975.70000109.9A211 T225 I256 Y383A211-V223 HydrophobicContact CB-CG2 3.97Å; A211-V223 WeakPolarHBondContact O-CG2 3.4Å; V223-T225 HydrophobicContact CG2-CG2 3.95Å; V223-I256 CarbonylContact C-O 3.42Å; V223-I256 VanDerWaalsContact CA-O 3.25Å; V223-I256 WeakPolarHBondContact CA-O 3.22Å; V223-I256 HydrophobicContact CG2-CB 4.21Å; V223-I256 HydrophobicContact CG2-CG2 4.37Å; V223-Y383 HydrophobicContact CB-CE1 4.3Å; V223-Y383 HydrophobicContact CB-CE2 4.33Å; V223-Y383 HydrophobicContact CG1-CD1 3.85Å; V223-Y383 HydrophobicContact CG1-CE1 3.29Å; V223-Y383 HydrophobicContact CG1-CE2 4.07Å; V223-Y383 HydrophobicContact CG1-CG 4.45Å; V223-Y383 VanDerWaalsContact CG1-CZ 3.42Å; V223-Y383 PolarHBondContact N-OH 3.2Å
224F97.3Very high94.6Very high2 Ų223.4 Ų23.41%0.00912%0.116CC..EExtended strand (participates in β ladder)trans-113123.4170-63.5-93.6000109.6W222 V230 W234 L238 I255 I256 S258 A261 I269 V274W222-F224 AromaticContact CD1-CD2 3.78Å; W222-F224 AromaticContact CD1-CE2 3.46Å; W222-F224 VanDerWaalsContact CD1-CE2 3.46Å; W222-F224 AromaticContact CD1-CZ 3.7Å; W222-F224 HydrophobicContact CG-CE2 4.37Å; W222-F224 AromaticContact NE1-CE1 3.91Å; W222-F224 AromaticContact NE1-CE2 3.99Å; W222-F224 AromaticContact NE1-CZ 3.77Å; F224-V230 HydrophobicContact CD1-CG1 3.9Å; F224-V230 HydrophobicContact CD1-CG2 3.97Å; F224-V230 HydrophobicContact CE1-CG1 3.98Å; F224-V230 HydrophobicContact CE1-CG2 3.87Å; F224-W234 HydrophobicContact CE1-CD2 4.05Å; F224-W234 AromaticContact CE1-CE3 3.87Å; F224-W234 HydrophobicContact CE1-CE3 3.87Å; F224-W234 HydrophobicContact CE1-CG 4.44Å; F224-W234 HydrophobicContact CE1-CZ3 4.36Å; F224-W234 HydrophobicContact CZ-CD2 4.38Å; F224-W234 AromaticContact CZ-CE3 3.73Å; F224-W234 HydrophobicContact CZ-CE3 3.73Å; F224-W234 AromaticContact CZ-CZ3 3.94Å; F224-W234 HydrophobicContact CZ-CZ3 3.94Å; F224-L238 HydrophobicContact CZ-CD2 4.34Å; F224-I255 HydrophobicContact CD2-CG2 4.04Å; F224-I255 HydrophobicContact CE2-CG2 3.69Å; F224-I256 PolarHBondContact N-O 2.91Å; F224-S258 VanDerWaalsContact O-CB 3.28Å; F224-S258 WeakPolarHBondContact O-CB 3.41Å; F224-S258 PolarHBondContact O-N 3.12Å; F224-A261 HydrophobicContact CB-CB 3.68Å; F224-I269 HydrophobicContact CD1-CD1 3.75Å; F224-I269 HydrophobicContact CD1-CG2 4.2Å; F224-I269 HydrophobicContact CE1-CD1 3.98Å; F224-I269 HydrophobicContact CE1-CG2 4.26Å; F224-V274 HydrophobicContact CD2-CG2 4.32Å; F224-V274 HydrophobicContact CE2-CG1 4.03Å; F224-V274 HydrophobicContact CE2-CG2 3.74Å; F224-V274 HydrophobicContact CZ-CG1 4.43Å; F224-V274 HydrophobicContact CZ-CG2 3.88Å
225T95.8Very high94.6Very high5 Ų524.2 Ų24.23%0.03112%0.121CC..BIsolated β-bridgetrans-136.8143.9-17753.70000111.2A211 L212 V223 E227 W228A211-T225 HydrophobicContact CB-CG2 4.23Å; L212-T225 HydrophobicContact CB-CG2 4.48Å; V223-T225 HydrophobicContact CG2-CG2 3.95Å; T225-E227 VanDerWaalsContact C-N 3.32Å; T225-E227 PolarHBondContact O-N 3.08Å; T225-W228 CarbonylContact O-C 3.53Å; T225-W228 VanDerWaalsContact O-C 3.28Å; T225-W228 PolarHBondContact O-N 3.32Å
226P94.7Very high94.6Very high8 Ų828.5 Ų28.55%0.05214%0.143CC..THydrogen-bonded Turntrans-63-32.9177.617.5-25.3000114W228 G260P226-W228 VanDerWaalsContact C-N 3.29Å; P226-W228 PolarHBondContact O-N 3.22Å; P226-G260 WeakPolarHBondContact CB-O 3.28Å
227E93.6Very high94.6Very high0 Ų031.3 Ų31.30%016%0.158CC..THydrogen-bonded Turntrans-74.4-21.5-178.9-63.388.5166.800113.3C207 G208 T225 I369 R372 F376C207-E227 VanDerWaalsContact CA-OE1 3.23Å; C207-E227 WeakPolarHBondContact CA-OE1 3.43Å; C207-E227 PolarHBondContact SG-OE1 3.32Å; G208-E227 VanDerWaalsContact CA-OE2 3.26Å; G208-E227 WeakPolarHBondContact CA-OE2 3.46Å; G208-E227 VanDerWaalsContact N-CD 3.34Å; G208-E227 PolarHBondContact N-OE1 3.41Å; G208-E227 VanDerWaalsContact N-OE1 3.12Å; G208-E227 PolarHBondContact N-OE2 2.95Å; T225-E227 VanDerWaalsContact C-N 3.32Å; T225-E227 PolarHBondContact O-N 3.08Å; E227-I369 HydrophobicContact CB-CG1 3.96Å; E227-I369 WeakPolarHBondContact O-CD1 3.36Å; E227-R372 HydrophobicContact CG-CG 4.33Å; E227-R372 IonicContact OE1-CZ 3.99Å; E227-R372 IonicContact OE1-NE 3.17Å; E227-R372 PolarHBondContact OE1-NE 2.79Å; E227-R372 IonicContact OE1-NH2 3.18Å; E227-R372 PolarHBondContact OE1-NH2 3.22Å; E227-F376 HydrophobicContact CB-CE1 4.03Å; E227-F376 HydrophobicContact CB-CZ 4.11Å; E227-F376 HydrophobicContact CG-CE1 4.2Å; E227-F376 HydrophobicContact CG-CZ 3.94Å
228W92.1Very high94.6Very high86 Ų8631.3 Ų31.333%0.32616%0.158SC..BIsolated β-bridgetrans-131.676175.5-171.956000110.6T225 P226 F380 Y383T225-W228 CarbonylContact O-C 3.53Å; T225-W228 VanDerWaalsContact O-C 3.28Å; T225-W228 PolarHBondContact O-N 3.32Å; P226-W228 VanDerWaalsContact C-N 3.29Å; P226-W228 PolarHBondContact O-N 3.22Å; W228-F380 HydrophobicContact CB-CD2 4.22Å; W228-F380 HydrophobicContact CB-CE2 3.46Å; W228-F380 VanDerWaalsContact CB-CE2 3.46Å; W228-F380 HydrophobicContact CB-CZ 4.05Å; W228-F380 AromaticContact CD1-CE2 3.98Å; W228-F380 AromaticContact CD1-CZ 3.64Å; W228-F380 AromaticContact CD2-CE2 3.18Å; W228-F380 HydrophobicContact CD2-CE2 3.18Å; W228-F380 AromaticContact CD2-CZ 3.22Å; W228-F380 HydrophobicContact CD2-CZ 3.22Å; W228-F380 AromaticContact CE2-CE2 3.84Å; W228-F380 AromaticContact CE2-CZ 3.33Å; W228-F380 HydrophobicContact CE3-CD2 4.49Å; W228-F380 AromaticContact CE3-CE2 3.28Å; W228-F380 HydrophobicContact CE3-CE2 3.28Å; W228-F380 AromaticContact CE3-CZ 3.65Å; W228-F380 HydrophobicContact CE3-CZ 3.65Å; W228-F380 HydrophobicContact CG-CD2 4.41Å; W228-F380 AromaticContact CG-CE2 3.27Å; W228-F380 HydrophobicContact CG-CE2 3.27Å; W228-F380 AromaticContact CG-CZ 3.4Å; W228-F380 HydrophobicContact CG-CZ 3.4Å; W228-F380 HydrophobicContact CH2-CE2 4.41Å; W228-F380 HydrophobicContact CH2-CZ 4.06Å; W228-F380 HydrophobicContact CZ2-CE2 4.41Å; W228-F380 AromaticContact CZ2-CZ 3.77Å; W228-F380 HydrophobicContact CZ2-CZ 3.77Å; W228-F380 AromaticContact CZ3-CE2 3.9Å; W228-F380 HydrophobicContact CZ3-CE2 3.9Å; W228-F380 HydrophobicContact CZ3-CZ 4.03Å; W228-F380 AromaticContact NE1-CZ 3.63Å; W228-Y383 HydrophobicContact CZ3-CE1 4.43Å
229P93.5Very high94.7Very high2 Ų230.9 Ų30.91%0.01316%0.155CC..PPolyproline II helixtrans-68.5138.8-178.924.3-28.9000110.9T262 D263 Q264 W365P229-T262 WeakPolarHBondContact CA-O 3.32Å; P229-T262 VanDerWaalsContact CB-O 3.22Å; P229-T262 WeakPolarHBondContact CB-O 3.27Å; P229-D263 VanDerWaalsContact CB-C 3.44Å; P229-D263 WeakPolarHBondContact CB-O 3.21Å; P229-Q264 HydrophobicContact CB-CG 4.27Å; P229-Q264 HydrophobicContact CG-CG 4.21Å; P229-Q264 WeakPolarHBondContact O-CG 3.44Å; P229-Q264 PolarHBondContact O-NE2 3Å; P229-W365 HydrophobicContact CG-CD2 3.51Å; P229-W365 VanDerWaalsContact CG-CE2 3.4Å; P229-W365 HydrophobicContact CG-CE3 4.05Å; P229-W365 HydrophobicContact CG-CG 3.77Å; P229-W365 HydrophobicContact CG-CH2 4.35Å; P229-W365 HydrophobicContact CG-CZ2 3.85Å; P229-W365 HydrophobicContact CG-CZ3 4.45Å
230V93.9Very high94.8Very high6 Ų636 Ų364%0.03618%0.177CC..BIsolated β-bridgetrans-72.2152.3178.4-65.70000111.1W222 F224 W234 D263 Q264 I269W222-V230 HydrophobicContact CZ2-CG1 4.24Å; F224-V230 HydrophobicContact CD1-CG1 3.9Å; F224-V230 HydrophobicContact CD1-CG2 3.97Å; F224-V230 HydrophobicContact CE1-CG1 3.98Å; F224-V230 HydrophobicContact CE1-CG2 3.87Å; V230-W234 HydrophobicContact CB-CB 3.69Å; V230-W234 HydrophobicContact CB-CG 4.31Å; V230-W234 HydrophobicContact CG1-CB 4.46Å; V230-W234 HydrophobicContact CG2-CB 3.51Å; V230-W234 HydrophobicContact CG2-CD2 4.45Å; V230-W234 HydrophobicContact CG2-CG 3.57Å; V230-D263 HydrophobicContact CG2-CB 4.37Å; V230-D263 WeakPolarHBondContact O-CA 3.38Å; V230-Q264 WeakPolarHBondContact O-CG 3.5Å; V230-Q264 PolarHBondContact O-N 3.38Å; V230-I269 HydrophobicContact CG2-CD1 3.39Å
231P94.5Very high94.8Very high39 Ų3937.2 Ų37.225%0.25318%0.181SC..PPolyproline II helixtrans-65.6163.3174.130.6-37.4000111.4N233 W234 L237P231-N233 WeakPolarHBondContact CB-OD1 3.49Å; P231-N233 VanDerWaalsContact CG-OD1 3.25Å; P231-N233 WeakPolarHBondContact CG-OD1 3.22Å; P231-N233 PolarHBondContact O-N 3.03Å; P231-W234 VanDerWaalsContact O-CB 3.26Å; P231-W234 WeakPolarHBondContact O-CB 3.48Å; P231-W234 VanDerWaalsContact O-CD1 3.32Å; P231-W234 PolarHBondContact O-N 3.22Å; P231-L237 HydrophobicContact CG-CD1 3.52Å
232E91.7Very high94.9Very high149 Ų14936.6 Ų36.670%0.69618%0.178SC*.THydrogen-bonded Turntrans-59.4-31.4-177.9-167.8176.3-174.600112.9W234 P235E232-W234 PolarHBondContact O-N 3.18Å; E232-P235 WeakPolarHBondContact O-CD 3.41Å
233N94.6Very high94.8Very high84 Ų8440.3 Ų40.345%0.44920%0.195SC..THydrogen-bonded Turntrans-8218.217573.4-25.3000114.2P231 P235 D236 L237P231-N233 WeakPolarHBondContact CB-OD1 3.49Å; P231-N233 VanDerWaalsContact CG-OD1 3.25Å; P231-N233 WeakPolarHBondContact CG-OD1 3.22Å; P231-N233 PolarHBondContact O-N 3.03Å; N233-P235 VanDerWaalsContact O-N 3.16Å; N233-D236 PolarHBondContact O-N 3.14Å; N233-D236 VanDerWaalsContact O-N 3.11Å; N233-L237 PolarHBondContact O-N 2.84Å
234W95.8Very high94.5Very high5 Ų543.2 Ų43.22%0.01921%0.209CC..Hα-helixtrans-51.6-3217672.7-96.5000115F224 V230 P231 E232 D236 L237 L238 I269 Q273 V274 V277F224-W234 HydrophobicContact CE1-CD2 4.05Å; F224-W234 AromaticContact CE1-CE3 3.87Å; F224-W234 HydrophobicContact CE1-CE3 3.87Å; F224-W234 HydrophobicContact CE1-CG 4.44Å; F224-W234 HydrophobicContact CE1-CZ3 4.36Å; F224-W234 HydrophobicContact CZ-CD2 4.38Å; F224-W234 AromaticContact CZ-CE3 3.73Å; F224-W234 HydrophobicContact CZ-CE3 3.73Å; F224-W234 AromaticContact CZ-CZ3 3.94Å; F224-W234 HydrophobicContact CZ-CZ3 3.94Å; V230-W234 HydrophobicContact CB-CB 3.69Å; V230-W234 HydrophobicContact CB-CG 4.31Å; V230-W234 HydrophobicContact CG1-CB 4.46Å; V230-W234 HydrophobicContact CG2-CB 3.51Å; V230-W234 HydrophobicContact CG2-CD2 4.45Å; V230-W234 HydrophobicContact CG2-CG 3.57Å; P231-W234 VanDerWaalsContact O-CB 3.26Å; P231-W234 WeakPolarHBondContact O-CB 3.48Å; P231-W234 VanDerWaalsContact O-CD1 3.32Å; P231-W234 PolarHBondContact O-N 3.22Å; E232-W234 PolarHBondContact O-N 3.18Å; W234-D236 VanDerWaalsContact C-N 3.27Å; W234-D236 PolarHBondContact O-N 3.44Å; W234-L237 PolarHBondContact O-N 3.14Å; W234-L238 HydrophobicContact CE3-CB 4.33Å; W234-L238 HydrophobicContact CE3-CD2 4.15Å; W234-L238 HydrophobicContact CZ3-CD2 3.79Å; W234-L238 VanDerWaalsContact O-CB 3.27Å; W234-L238 WeakPolarHBondContact O-CB 3.1Å; W234-L238 PolarHBondContact O-N 3.04Å; W234-I269 HydrophobicContact CZ2-CG2 4.26Å; W234-Q273 HydrophobicContact CH2-CG 4.35Å; W234-Q273 HydrophobicContact CZ2-CG 4.14Å; W234-V274 HydrophobicContact CH2-CG2 3.96Å; W234-V274 HydrophobicContact CZ3-CG2 4.15Å; W234-V277 HydrophobicContact CH2-CB 4.12Å; W234-V277 HydrophobicContact CH2-CG1 4.38Å; W234-V277 HydrophobicContact CH2-CG2 3.7Å; W234-V277 HydrophobicContact CZ2-CG2 4.36Å; W234-V277 HydrophobicContact CZ3-CB 4.25Å; W234-V277 HydrophobicContact CZ3-CG1 4.07Å; W234-V277 HydrophobicContact CZ3-CG2 4.24Å
235P96.9Very high94.1Very high16 Ų1643.1 Ų43.110%0.10421%0.208CC..Hα-helixtrans-59.1-39.2177.6-29.841.2000112.6E232 N233 C239 V277 R281E232-P235 WeakPolarHBondContact O-CD 3.41Å; N233-P235 VanDerWaalsContact O-N 3.16Å; P235-C239 VanDerWaalsContact O-CB 3.31Å; P235-C239 WeakPolarHBondContact O-CB 3.17Å; P235-C239 PolarHBondContact O-N 3.15Å; P235-C239 VanDerWaalsContact O-N 3.07Å; P235-C239 PolarHBondContact O-SG 2.99Å; P235-V277 HydrophobicContact CB-CG1 3.65Å; P235-V277 HydrophobicContact CB-CG2 4.25Å; P235-V277 HydrophobicContact CG-CG1 4.48Å; P235-V277 HydrophobicContact CG-CG2 4.36Å; P235-R281 VanDerWaalsContact CB-CZ 3.42Å
236D96.6Very high93.8Very high92 Ų9244.6 Ų44.649%0.49221%0.213SC..Hα-helixtrans-71-43.9177.9-69.2-65.9000111.7N233 W234 C239 K240 R281N233-D236 PolarHBondContact O-N 3.14Å; N233-D236 VanDerWaalsContact O-N 3.11Å; W234-D236 VanDerWaalsContact C-N 3.27Å; W234-D236 PolarHBondContact O-N 3.44Å; D236-C239 PolarHBondContact O-N 3.41Å; D236-K240 VanDerWaalsContact O-CB 3.27Å; D236-K240 WeakPolarHBondContact O-CB 3.41Å; D236-K240 PolarHBondContact O-N 3.33Å; D236-R281 IonicContact OD1-CZ 3.88Å; D236-R281 IonicContact OD1-NH1 2.76Å; D236-R281 PolarHBondContact OD1-NH1 2.97Å; D236-R281 IonicContact OD2-CZ 3.98Å; D236-R281 IonicContact OD2-NH1 3.22Å; D236-R281 PolarHBondContact OD2-NH1 2.83Å
237L95Very high93.5Very high68 Ų6849.7 Ų49.736%0.35624%0.24SC..Hα-helixtrans-63.5-44.8179.4-62.8175.9000111.8W222 P231 N233 W234 K241W222-L237 HydrophobicContact CH2-CB 3.92Å; P231-L237 HydrophobicContact CG-CD1 3.52Å; N233-L237 PolarHBondContact O-N 2.84Å; W234-L237 PolarHBondContact O-N 3.14Å; L237-K241 PolarHBondContact O-N 3.44Å; L237-K241 VanDerWaalsContact O-N 3.09Å
238L95.9Very high93Very high0 Ų055.5 Ų55.50%026%0.263CS..Hα-helixtrans-60.7-55176.1176.666.4000110W222 F224 W234 K240 K241 L242 I255 V274 V278W222-L238 HydrophobicContact CB-CD1 3.68Å; W222-L238 HydrophobicContact CD2-CD1 3.76Å; W222-L238 HydrophobicContact CE3-CD1 3.88Å; W222-L238 HydrophobicContact CG-CD1 3.64Å; F224-L238 HydrophobicContact CZ-CD2 4.34Å; W234-L238 HydrophobicContact CE3-CB 4.33Å; W234-L238 HydrophobicContact CE3-CD2 4.15Å; W234-L238 HydrophobicContact CZ3-CD2 3.79Å; W234-L238 VanDerWaalsContact O-CB 3.27Å; W234-L238 WeakPolarHBondContact O-CB 3.1Å; W234-L238 PolarHBondContact O-N 3.04Å; L238-K240 VanDerWaalsContact C-N 3.28Å; L238-K240 PolarHBondContact O-N 2.96Å; L238-K241 PolarHBondContact O-N 3.26Å; L238-K241 VanDerWaalsContact O-N 3.13Å; L238-L242 HydrophobicContact CD1-CD1 3.88Å; L238-L242 HydrophobicContact CD1-CD2 4.31Å; L238-L242 HydrophobicContact CD1-CG 3.96Å; L238-L242 HydrophobicContact CD2-CD1 4.47Å; L238-L242 HydrophobicContact CG-CD1 3.86Å; L238-L242 HydrophobicContact CG-CG 4.26Å; L238-L242 VanDerWaalsContact O-CG 3.31Å; L238-L242 WeakPolarHBondContact O-CG 3.42Å; L238-L242 PolarHBondContact O-N 3.49Å; L238-I255 HydrophobicContact CD1-CD1 4.14Å; L238-I255 HydrophobicContact CD1-CG1 4.4Å; L238-I255 HydrophobicContact CD2-CD1 4.38Å; L238-V274 HydrophobicContact CD2-CG1 3.87Å; L238-V278 HydrophobicContact CD2-CG2 3.83Å; L238-V278 HydrophobicContact CG-CG2 4.48Å
239C96.1Very high92.6Very high10 Ų1054.1 Ų54.17%0.06828%0.275CS..Hα-helixtrans-61.8-37.5-176.2-73.10000112.5P235 D236 K243 R281 L282P235-C239 VanDerWaalsContact O-CB 3.31Å; P235-C239 WeakPolarHBondContact O-CB 3.17Å; P235-C239 PolarHBondContact O-N 3.15Å; P235-C239 VanDerWaalsContact O-N 3.07Å; P235-C239 PolarHBondContact O-SG 2.99Å; D236-C239 PolarHBondContact O-N 3.41Å; C239-K243 VanDerWaalsContact O-CB 3.3Å; C239-K243 WeakPolarHBondContact O-CB 3.26Å; C239-K243 PolarHBondContact O-N 3.41Å; C239-R281 HydrophobicContact CB-CB 4.47Å; C239-L282 HydrophobicContact CB-CD1 4.05Å; C239-L282 HydrophobicContact CB-CD2 4.06Å; C239-L282 HydrophobicContact CB-CG 3.95Å
240K95Very high92.2Very high133 Ų13355.6 Ų55.658%0.57828%0.282SS*.Hα-helixtrans-59.2-51.7173.2-179.8178.5174.9-1800111.2D236 L238 L242 K243 E244D236-K240 VanDerWaalsContact O-CB 3.27Å; D236-K240 WeakPolarHBondContact O-CB 3.41Å; D236-K240 PolarHBondContact O-N 3.33Å; L238-K240 VanDerWaalsContact C-N 3.28Å; L238-K240 PolarHBondContact O-N 2.96Å; K240-L242 PolarHBondContact O-N 3.49Å; K240-K243 PolarHBondContact O-N 3.49Å; K240-E244 WeakPolarHBondContact CE-OE1 3.48Å; K240-E244 WeakPolarHBondContact CG-OE1 3.22Å; K240-E244 WeakPolarHBondContact O-CG 3.34Å; K240-E244 PolarHBondContact O-N 3.15Å
241K93Very high91.9Very high29 Ų2960.1 Ų60.113%0.12630%0.298CS..Hα-helixtrans-61.9-44.3-178.2-168.4-175.4-171.6178.80112.2D221 W222 L237 L238 K243 E244 S245 S387 M389D221-K241 WeakPolarHBondContact O-CD 3.41Å; D221-K241 WeakPolarHBondContact O-CE 3.27Å; D221-K241 PolarHBondContact O-NZ 3.38Å; W222-K241 HydrophobicContact CE3-CB 4.24Å; W222-K241 HydrophobicContact CE3-CD 3.47Å; W222-K241 VanDerWaalsContact CE3-CD 3.47Å; W222-K241 HydrophobicContact CE3-CG 4.48Å; W222-K241 HydrophobicContact CZ3-CB 4.06Å; W222-K241 HydrophobicContact CZ3-CD 3.65Å; W222-K241 HydrophobicContact CZ3-CG 4.49Å; L237-K241 PolarHBondContact O-N 3.44Å; L237-K241 VanDerWaalsContact O-N 3.09Å; L238-K241 PolarHBondContact O-N 3.26Å; L238-K241 VanDerWaalsContact O-N 3.13Å; K241-K243 VanDerWaalsContact C-N 3.35Å; K241-E244 PolarHBondContact O-N 3.34Å; K241-S245 WeakPolarHBondContact O-CB 3.39Å; K241-S245 PolarHBondContact O-N 3.24Å; K241-S387 WeakPolarHBondContact CE-O 3.27Å; K241-S387 PolarHBondContact NZ-O 3.48Å; K241-S387 PolarHBondContact NZ-OG 2.97Å; K241-M389 HydrophobicContact CG-CG 4.34Å
242L94.4Very high91.8Very high0 Ų059.5 Ų59.50%029%0.293CS..Hα-helixtrans-65.1-39.7179.1-63.8179.8000111.9D221 L238 K240 S245 R246 N253 I255 V278 L282 Y284D221-L242 HydrophobicContact CB-CD2 3.97Å; L238-L242 HydrophobicContact CD1-CD1 3.88Å; L238-L242 HydrophobicContact CD1-CD2 4.31Å; L238-L242 HydrophobicContact CD1-CG 3.96Å; L238-L242 HydrophobicContact CD2-CD1 4.47Å; L238-L242 HydrophobicContact CG-CD1 3.86Å; L238-L242 HydrophobicContact CG-CG 4.26Å; L238-L242 VanDerWaalsContact O-CG 3.31Å; L238-L242 WeakPolarHBondContact O-CG 3.42Å; L238-L242 PolarHBondContact O-N 3.49Å; K240-L242 PolarHBondContact O-N 3.49Å; L242-S245 WeakPolarHBondContact O-CB 3.29Å; L242-S245 PolarHBondContact O-N 3.12Å; L242-R246 WeakPolarHBondContact O-CG 3.45Å; L242-R246 PolarHBondContact O-N 2.97Å; L242-N253 HydrophobicContact CD2-CB 3.8Å; L242-I255 HydrophobicContact CD1-CD1 3.89Å; L242-I255 HydrophobicContact CD2-CD1 4.38Å; L242-I255 HydrophobicContact CD2-CG1 4.4Å; L242-V278 HydrophobicContact CD1-CG1 4.07Å; L242-V278 HydrophobicContact CD1-CG2 3.66Å; L242-L282 HydrophobicContact CB-CD1 3.79Å; L242-L282 HydrophobicContact CD1-CD1 4.24Å; L242-Y284 HydrophobicContact CB-CE2 4.46Å
243K94.1Very high91.8Very high110 Ų11052.4 Ų52.448%0.47826%0.26SS..Hα-helixtrans-63.6-48.6176.2-176.4175.4178.2177.30111.3C239 K240 K241 S245 R246 D247 L282C239-K243 VanDerWaalsContact O-CB 3.3Å; C239-K243 WeakPolarHBondContact O-CB 3.26Å; C239-K243 PolarHBondContact O-N 3.41Å; K240-K243 PolarHBondContact O-N 3.49Å; K241-K243 VanDerWaalsContact C-N 3.35Å; K243-S245 VanDerWaalsContact C-N 3.29Å; K243-S245 PolarHBondContact O-N 3.36Å; K243-R246 PolarHBondContact O-N 3.16Å; K243-R246 VanDerWaalsContact O-N 3.13Å; K243-D247 PolarHBondContact O-N 3.42Å; K243-L282 HydrophobicContact CB-CD2 4.09Å
244E90.6Very high91.9Very high64 Ų6448.9 Ų48.930%0.29924%0.242SC..Hα-helixtrans-55.4-47.1175.1-72.2171.4-177.800110.6K240 K241 R246 D247 Y248 M389K240-E244 WeakPolarHBondContact CE-OE1 3.48Å; K240-E244 WeakPolarHBondContact CG-OE1 3.22Å; K240-E244 WeakPolarHBondContact O-CG 3.34Å; K240-E244 PolarHBondContact O-N 3.15Å; K241-E244 PolarHBondContact O-N 3.34Å; E244-R246 VanDerWaalsContact C-N 3.35Å; E244-R246 PolarHBondContact O-N 2.7Å; E244-D247 PolarHBondContact O-N 3.04Å; E244-Y248 WeakPolarHBondContact O-CD2 3.46Å; E244-Y248 PolarHBondContact O-N 3.3Å; E244-M389 HydrophobicContact CB-CG 4.39Å
245S88.8Confident91.9Very high0 Ų048.7 Ų48.70%024%0.241CC..Hα-helixtrans-51.2-48.5174.31620000113.6D221 K241 L242 K243 Y248 Q250 N253 M389D221-S245 PolarHBondContact OD1-OG 3.29Å; K241-S245 WeakPolarHBondContact O-CB 3.39Å; K241-S245 PolarHBondContact O-N 3.24Å; L242-S245 WeakPolarHBondContact O-CB 3.29Å; L242-S245 PolarHBondContact O-N 3.12Å; K243-S245 VanDerWaalsContact C-N 3.29Å; K243-S245 PolarHBondContact O-N 3.36Å; S245-Y248 PolarHBondContact O-N 2.96Å; S245-Q250 VanDerWaalsContact CB-OE1 3.26Å; S245-Q250 WeakPolarHBondContact O-CB 3.39Å; S245-Q250 PolarHBondContact O-N 3.22Å; S245-Q250 VanDerWaalsContact O-N 3.14Å; S245-Q250 WeakPolarHBondContact OG-CB 3.48Å; S245-Q250 PolarHBondContact OG-OE1 3.38Å; S245-N253 PolarHBondContact OG-ND2 2.86Å; S245-M389 VanDerWaalsContact CA-CE 3.46Å
246R88.9Confident92Very high35 Ų3547.9 Ų47.913%0.13224%0.236CC..Hα-helixtrans-67.4-40.8177.1-67.4-48.7-1711201.5113.3Q195 R196 L242 K243 E244 Y248 G249 Q250 R251 N253 Y284Q195-R246 VanDerWaalsContact C-NH2 3.35Å; Q195-R246 VanDerWaalsContact O-CZ 3.31Å; Q195-R246 PolarHBondContact O-NH1 3.29Å; Q195-R246 PolarHBondContact O-NH2 3Å; R196-R246 VanDerWaalsContact C-NH2 3.3Å; R196-R246 PolarHBondContact O-NH2 2.77Å; R196-R246 VanDerWaalsContact O-NH2 3.16Å; L242-R246 WeakPolarHBondContact O-CG 3.45Å; L242-R246 PolarHBondContact O-N 2.97Å; K243-R246 PolarHBondContact O-N 3.16Å; K243-R246 VanDerWaalsContact O-N 3.13Å; E244-R246 VanDerWaalsContact C-N 3.35Å; E244-R246 PolarHBondContact O-N 2.7Å; R246-Y248 PolarHBondContact O-N 3.49Å; R246-G249 WeakPolarHBondContact O-CA 3.48Å; R246-G249 PolarHBondContact O-N 3.23Å; R246-Q250 WeakPolarHBondContact CD-O 3.27Å; R246-R251 PolarHBondContact NH1-O 3.09Å; R246-R251 PolarHBondContact NH2-O 3.06Å; R246-N253 PolarHBondContact NE-OD1 3.46Å; R246-Y284 HydrophobicContact CB-CE2 4.49Å; R246-Y284 WeakPolarHBondContact CB-OH 3.39Å; R246-Y284 HydrophobicContact CG-CD2 4.45Å; R246-Y284 HydrophobicContact CG-CE2 3.48Å; R246-Y284 VanDerWaalsContact CG-CE2 3.48Å; R246-Y284 VanDerWaalsContact CG-OH 3.31Å; R246-Y284 WeakPolarHBondContact CG-OH 3.38Å
247D89.1Confident92.1Very high115 Ų11543.6 Ų43.662%0.61521%0.213SC*.Hα-helixtrans-62.2-30.4179.5-67.5-16.5000111.1K243 E244 G249K243-D247 PolarHBondContact O-N 3.42Å; E244-D247 PolarHBondContact O-N 3.04Å; D247-G249 VanDerWaalsContact C-N 3.28Å; D247-G249 PolarHBondContact O-N 3Å
248Y83Confident92.2Very high123 Ų12340.4 Ų40.448%0.48220%0.196SC..THydrogen-bonded Turntrans-81.10.4172.6-81.9-76.8000115E244 S245 R246 M389 H390 H457E244-Y248 WeakPolarHBondContact O-CD2 3.46Å; E244-Y248 PolarHBondContact O-N 3.3Å; S245-Y248 PolarHBondContact O-N 2.96Å; R246-Y248 PolarHBondContact O-N 3.49Å; Y248-M389 HydrophobicContact CD2-CE 4.35Å; Y248-H390 AromaticContact CD2-CE1 3.67Å; Y248-H390 AromaticContact CE1-CE1 3.74Å; Y248-H390 AromaticContact CE2-CE1 2.99Å; Y248-H390 WeakPolarHBondContact CE2-CE1 3.49Å; Y248-H390 AromaticContact CE2-NE2 3.16Å; Y248-H390 WeakPolarHBondContact CE2-NE2 3.47Å; Y248-H390 AromaticContact CZ-CE1 3Å; Y248-H390 AromaticContact CZ-NE2 3.4Å; Y248-H390 PolarHBondContact OH-CE1 3.03Å; Y248-H390 PolarHBondContact OH-NE2 3.49Å; Y248-H390 VanDerWaalsContact OH-NE2 3.14Å; Y248-H457 AromaticContact CD1-CE1 3.58Å; Y248-H457 AromaticContact CD1-NE2 3.47Å; Y248-H457 WeakPolarHBondContact CD1-NE2 3.34Å; Y248-H457 AromaticContact CE1-CE1 3.93Å; Y248-H457 AromaticContact CG-NE2 3.54Å
249G84Confident92.2Very high56 Ų5644.5 Ų44.558%0.57722%0.215SC*.THydrogen-bonded Turntrans95.56.117400000115.2R246 D247 R251R246-G249 WeakPolarHBondContact O-CA 3.48Å; R246-G249 PolarHBondContact O-N 3.23Å; D247-G249 VanDerWaalsContact C-N 3.28Å; D247-G249 PolarHBondContact O-N 3Å; G249-R251 PolarHBondContact O-N 3.43Å
250Q85.1Confident92.1Very high33 Ų3344.8 Ų44.815%0.15422%0.22CC..  trans-63.5129.2168.5-72.7-175.3-61.300109.1S245 R246 I460S245-Q250 VanDerWaalsContact CB-OE1 3.26Å; S245-Q250 WeakPolarHBondContact O-CB 3.39Å; S245-Q250 PolarHBondContact O-N 3.22Å; S245-Q250 VanDerWaalsContact O-N 3.14Å; S245-Q250 WeakPolarHBondContact OG-CB 3.48Å; S245-Q250 PolarHBondContact OG-OE1 3.38Å; R246-Q250 WeakPolarHBondContact CD-O 3.27Å; Q250-I460 HydrophobicContact CG-CD1 4.12Å
251R87.3Confident92.2Very high102 Ų10238.6 Ų38.639%0.38519%0.194SC..  trans-89.9-17.8-179.4-65.4178.158.677.61.1112.5Q192 S193 Q195 R246 G249Q192-R251 PolarHBondContact O-NE 3.36Å; Q192-R251 PolarHBondContact O-NH2 3.23Å; S193-R251 PolarHBondContact O-NH2 2.86Å; Q195-R251 CarbonylContact C-O 3.52Å; Q195-R251 VanDerWaalsContact C-O 3.3Å; Q195-R251 WeakPolarHBondContact CA-O 3.49Å; Q195-R251 HydrophobicContact CG-CB 4.49Å; Q195-R251 VanDerWaalsContact CG-CZ 3.47Å; Q195-R251 VanDerWaalsContact CG-NH2 3.28Å; R246-R251 PolarHBondContact NH1-O 3.09Å; R246-R251 PolarHBondContact NH2-O 3.06Å; G249-R251 PolarHBondContact O-N 3.43Å
252V90.9Very high92.2Very high25 Ų2538.6 Ų38.615%0.15220%0.196CC..  trans-125.8140.7-173.3179.40000107.8A191 Q192 I254A191-V252 VanDerWaalsContact C-CG2 3.48Å; A191-V252 HydrophobicContact CB-CB 4.28Å; A191-V252 HydrophobicContact CB-CG1 3.52Å; A191-V252 HydrophobicContact CB-CG2 3.81Å; Q192-V252 HydrophobicContact CB-CG2 3.75Å; Q192-V252 HydrophobicContact CG-CG2 4.39Å; V252-I254 HydrophobicContact CG1-CD1 3.69Å; V252-I254 HydrophobicContact CG1-CG1 3.92Å
253N93.6Very high92.2Very high0 Ų039.1 Ų39.10%020%0.199CC..EExtended strand (participates in β ladder)trans-119.8131.5160.7-60.6119.7000110.4R196 T197 F198 D221 L242 S245 R246R196-N253 PolarHBondContact O-N 3.24Å; T197-N253 CarbonylContact C-O 3.4Å; T197-N253 WeakPolarHBondContact CA-O 3.27Å; T197-N253 HydrophobicContact CG2-CB 3.81Å; T197-N253 PolarHBondContact OG1-OD1 3.2Å; F198-N253 PolarHBondContact N-O 3Å; D221-N253 PolarHBondContact OD1-ND2 3.22Å; D221-N253 WeakPolarHBondContact OD2-CA 3.39Å; L242-N253 HydrophobicContact CD2-CB 3.8Å; S245-N253 PolarHBondContact OG-ND2 2.86Å; R246-N253 PolarHBondContact NE-OD1 3.46Å
254I95.1Very high92.2Very high11 Ų1138.4 Ų38.46%0.05620%0.197CC..EExtended strand (participates in β ladder)trans-114.1122.2173.9-57.4-57.8000108.4I184 V187 F198 I200 A220 D221 W222 V252 I256I184-I254 HydrophobicContact CG2-CG2 4.23Å; V187-I254 HydrophobicContact CG1-CD1 4.49Å; F198-I254 HydrophobicContact CB-CD1 4.04Å; I200-I254 HydrophobicContact CD1-CG2 3.96Å; A220-I254 HydrophobicContact CB-CB 4.46Å; A220-I254 HydrophobicContact CB-CG2 4.16Å; D221-I254 PolarHBondContact N-O 2.93Å; D221-I254 PolarHBondContact OD2-N 3.38Å; W222-I254 PolarHBondContact N-O 3.06Å; V252-I254 HydrophobicContact CG1-CD1 3.69Å; V252-I254 HydrophobicContact CG1-CG1 3.92Å; I254-I256 HydrophobicContact CG2-CG1 4.16Å
255I97.5Very high92.2Very high0 Ų038.6 Ų38.60%020%0.203CC..EExtended strand (participates in β ladder)trans-116126175.1-59.2161.5000107T197 F198 V199 I200 W222 F224 L238 L242 V274 V278T197-I255 HydrophobicContact CG2-CD1 3.77Å; T197-I255 HydrophobicContact CG2-CG1 4.49Å; F198-I255 PolarHBondContact O-N 2.99Å; V199-I255 CarbonylContact C-O 3.6Å; V199-I255 WeakPolarHBondContact CA-O 3.22Å; V199-I255 HydrophobicContact CG1-CG2 4.45Å; V199-I255 HydrophobicContact CG2-CB 4.37Å; V199-I255 HydrophobicContact CG2-CD1 4.18Å; I200-I255 PolarHBondContact N-O 3.42Å; W222-I255 HydrophobicContact CB-CG1 4.3Å; W222-I255 HydrophobicContact CB-CG2 4.19Å; W222-I255 WeakPolarHBondContact O-CA 3.47Å; F224-I255 HydrophobicContact CD2-CG2 4.04Å; F224-I255 HydrophobicContact CE2-CG2 3.69Å; L238-I255 HydrophobicContact CD1-CD1 4.14Å; L238-I255 HydrophobicContact CD1-CG1 4.4Å; L238-I255 HydrophobicContact CD2-CD1 4.38Å; L242-I255 HydrophobicContact CD1-CD1 3.89Å; L242-I255 HydrophobicContact CD2-CD1 4.38Å; L242-I255 HydrophobicContact CD2-CG1 4.4Å; I255-V274 HydrophobicContact CD1-CG1 4.13Å; I255-V274 HydrophobicContact CG2-CG1 4.02Å; I255-V278 HydrophobicContact CD1-CG2 4.13Å
256I98Very high92.2Very high0 Ų040.3 Ų40.30%022%0.221CC..EExtended strand (participates in β ladder)trans-105.4126.6178.6-60.3-178.4000109.2I184 I200 V202 A211 A214 A220 W222 V223 F224 I254I184-I256 HydrophobicContact CD1-CD1 3.75Å; I200-I256 WeakPolarHBondContact O-CA 3.19Å; V202-I256 HydrophobicContact CB-CG2 4.29Å; V202-I256 HydrophobicContact CG2-CG2 3.7Å; A211-I256 HydrophobicContact CB-CG2 3.8Å; A214-I256 HydrophobicContact CB-CD1 3.79Å; A220-I256 HydrophobicContact CB-CD1 3.81Å; A220-I256 HydrophobicContact CB-CG1 3.9Å; W222-I256 PolarHBondContact O-N 2.85Å; V223-I256 CarbonylContact C-O 3.42Å; V223-I256 VanDerWaalsContact CA-O 3.25Å; V223-I256 WeakPolarHBondContact CA-O 3.22Å; V223-I256 HydrophobicContact CG2-CB 4.21Å; V223-I256 HydrophobicContact CG2-CG2 4.37Å; F224-I256 PolarHBondContact N-O 2.91Å; I254-I256 HydrophobicContact CG2-CG1 4.16Å
257C97.8Very high92.4Very high1 Ų144.7 Ų44.71%0.00724%0.241CC..EExtended strand (participates in β ladder)trans-115.5118.3178-164.60000109.4V199 I200 E201 V202V199-C257 HydrophobicContact CG1-CB 4.39Å; I200-C257 PolarHBondContact O-N 3.23Å; E201-C257 WeakPolarHBondContact CA-O 3.43Å; V202-C257 PolarHBondContact N-O 3.32Å
258S97.5Very high92.7Very high1 Ų142.7 Ų42.71%0.00724%0.24CC..EExtended strand (participates in β ladder)trans-65.3143.1166.1177.40000109.7F224 G260 A261F224-S258 VanDerWaalsContact O-CB 3.28Å; F224-S258 WeakPolarHBondContact O-CB 3.41Å; F224-S258 PolarHBondContact O-N 3.12Å; S258-G260 PolarHBondContact O-N 2.95Å; S258-G260 VanDerWaalsContact O-N 3.14Å; S258-G260 PolarHBondContact OG-N 2.84Å; S258-A261 WeakPolarHBondContact O-CB 3.44Å; S258-A261 PolarHBondContact O-N 2.87Å
259E95.7Very high93.3Very high86 Ų8637.2 Ų37.240%0.40222%0.219SC..THydrogen-bonded Turntrans-59.1-22.6173.569.9-175.8165.900113.2V202 G204 R205V202-E259 PolarHBondContact O-N 2.87Å; G204-E259 PolarHBondContact N-OE1 2.93Å; R205-E259 VanDerWaalsContact CA-OE1 3.27Å; R205-E259 WeakPolarHBondContact CA-OE1 3.38Å; R205-E259 PolarHBondContact N-OE1 3.3Å
260G95Very high93.9Very high17 Ų1737.4 Ų37.418%0.17521%0.212CC..THydrogen-bonded Turntrans-94.712.9175.800000114.9R205 P226 S258R205-G260 WeakPolarHBondContact O-CA 3.44Å; R205-G260 PolarHBondContact O-N 3.2Å; P226-G260 WeakPolarHBondContact CB-O 3.28Å; S258-G260 PolarHBondContact O-N 2.95Å; S258-G260 VanDerWaalsContact O-N 3.14Å; S258-G260 PolarHBondContact OG-N 2.84Å
261A96Very high94.5Very high2 Ų236.2 Ų36.22%0.01721%0.207CC..  trans-63134.5-174.400000113.5F224 S258 A268 I269F224-A261 HydrophobicContact CB-CB 3.68Å; S258-A261 WeakPolarHBondContact O-CB 3.44Å; S258-A261 PolarHBondContact O-N 2.87Å; A261-A268 WeakPolarHBondContact O-CA 3.39Å; A261-I269 HydrophobicContact CB-CB 4.34Å; A261-I269 PolarHBondContact O-N 2.97Å
262T94.6Very high95Very high30 Ų3035.4 Ų35.418%0.18421%0.208CC..BIsolated β-bridgetrans-135.2159.9175.360.90000111.6P229 K267P229-T262 WeakPolarHBondContact CA-O 3.32Å; P229-T262 VanDerWaalsContact CB-O 3.22Å; P229-T262 WeakPolarHBondContact CB-O 3.27Å; T262-K267 CarbonylContact C-O 3.09Å; T262-K267 VanDerWaalsContact CA-O 3.23Å; T262-K267 WeakPolarHBondContact CA-O 3.41Å
263D94.5Very high95.2Very high10 Ų1037.1 Ų37.15%0.05321%0.214CC..BIsolated β-bridgetrans-85.9175.7162.36924.1000111.6P229 V230 T265 G266 K267 I269P229-D263 VanDerWaalsContact CB-C 3.44Å; P229-D263 WeakPolarHBondContact CB-O 3.21Å; V230-D263 HydrophobicContact CG2-CB 4.37Å; V230-D263 WeakPolarHBondContact O-CA 3.38Å; D263-T265 PolarHBondContact O-N 3.41Å; D263-T265 WeakPolarHBondContact OD1-CA 3.4Å; D263-T265 WeakPolarHBondContact OD1-CB 3.15Å; D263-T265 PolarHBondContact OD1-N 3.31Å; D263-T265 PolarHBondContact OD1-OG1 3.26Å; D263-T265 PolarHBondContact OD2-OG1 2.92Å; D263-G266 WeakPolarHBondContact O-CA 3.22Å; D263-G266 PolarHBondContact O-N 3.22Å; D263-G266 PolarHBondContact OD1-N 3.2Å; D263-G266 VanDerWaalsContact OD1-N 3.12Å; D263-K267 PolarHBondContact N-O 3.34Å; D263-K267 PolarHBondContact OD1-N 3.01Å; D263-K267 WeakPolarHBondContact OD2-CB 3.43Å; D263-I269 HydrophobicContact CB-CD1 4.07Å; D263-I269 HydrophobicContact CB-CG1 4.45Å
264Q93.1Very high95.4Very high95 Ų9537.1 Ų37.144%0.44421%0.214SC..THydrogen-bonded Turntrans-64.3-19.7-179.4-75.1173.9-1.200113.7P229 V230 G266P229-Q264 HydrophobicContact CB-CG 4.27Å; P229-Q264 HydrophobicContact CG-CG 4.21Å; P229-Q264 WeakPolarHBondContact O-CG 3.44Å; P229-Q264 PolarHBondContact O-NE2 3Å; V230-Q264 WeakPolarHBondContact O-CG 3.5Å; V230-Q264 PolarHBondContact O-N 3.38Å; Q264-G266 PolarHBondContact O-N 2.88Å
265T91.2Very high95.6Very high68 Ų6839.1 Ų39.142%0.41722%0.221SC..THydrogen-bonded Turntrans-78.2-12.8173.879.50000111.7D263 K267 K363D263-T265 PolarHBondContact O-N 3.41Å; D263-T265 WeakPolarHBondContact OD1-CA 3.4Å; D263-T265 WeakPolarHBondContact OD1-CB 3.15Å; D263-T265 PolarHBondContact OD1-N 3.31Å; D263-T265 PolarHBondContact OD1-OG1 3.26Å; D263-T265 PolarHBondContact OD2-OG1 2.92Å; T265-K267 PolarHBondContact OG1-N 3.33Å; T265-K363 WeakPolarHBondContact O-CE 3.4Å; T265-K363 PolarHBondContact O-NZ 3.26Å
266G87.6Confident95.6Very high37 Ų3742.5 Ų42.538%0.38124%0.237SC..SBendtrans88.98.5-174.200000113.1D263 Q264D263-G266 WeakPolarHBondContact O-CA 3.22Å; D263-G266 PolarHBondContact O-N 3.22Å; D263-G266 PolarHBondContact OD1-N 3.2Å; D263-G266 VanDerWaalsContact OD1-N 3.12Å; Q264-G266 PolarHBondContact O-N 2.88Å
267K93.7Very high95.5Very high126 Ų12643.6 Ų43.655%0.54824%0.243SC..  trans-76.6131.5176.2-176-177.8177.6179.70109.2T262 D263 T265T262-K267 CarbonylContact C-O 3.09Å; T262-K267 VanDerWaalsContact CA-O 3.23Å; T262-K267 WeakPolarHBondContact CA-O 3.41Å; D263-K267 PolarHBondContact N-O 3.34Å; D263-K267 PolarHBondContact OD1-N 3.01Å; D263-K267 WeakPolarHBondContact OD2-CB 3.43Å; T265-K267 PolarHBondContact OG1-N 3.33Å
268A95.1Very high95.5Very high73 Ų7343.5 Ų43.560%0.60324%0.243SC*.BIsolated β-bridgetrans-62.8139176.900000111.2A261A261-A268 WeakPolarHBondContact O-CA 3.39Å
269I96.6Very high95.4Very high8 Ų846.8 Ų46.84%0.04126%0.258CS..  trans-108.6116.4174.9-60.2174.9000107.6F224 V230 W234 A261 D263 V274F224-I269 HydrophobicContact CD1-CD1 3.75Å; F224-I269 HydrophobicContact CD1-CG2 4.2Å; F224-I269 HydrophobicContact CE1-CD1 3.98Å; F224-I269 HydrophobicContact CE1-CG2 4.26Å; V230-I269 HydrophobicContact CG2-CD1 3.39Å; W234-I269 HydrophobicContact CZ2-CG2 4.26Å; A261-I269 HydrophobicContact CB-CB 4.34Å; A261-I269 PolarHBondContact O-N 2.97Å; D263-I269 HydrophobicContact CB-CD1 4.07Å; D263-I269 HydrophobicContact CB-CG1 4.45Å; I269-V274 HydrophobicContact CG2-CG2 3.67Å
270S96.6Very high95.4Very high60 Ų6046 Ų4642%0.4226%0.256SS..  trans-90.8152175.970.90000111.9E272 Q273 V274S270-E272 PolarHBondContact O-N 3Å; S270-Q273 WeakPolarHBondContact O-CB 3.06Å; S270-Q273 PolarHBondContact O-N 2.92Å; S270-Q273 VanDerWaalsContact O-N 3.1Å; S270-Q273 WeakPolarHBondContact OG-CB 3.24Å; S270-Q273 PolarHBondContact OG-N 3.36Å; S270-Q273 VanDerWaalsContact OG-N 3.1Å; S270-V274 PolarHBondContact O-N 3.42Å; S270-V274 VanDerWaalsContact O-N 3.13Å
271S96.8Very high95.5Very high8 Ų851 Ų516%0.05627%0.27CS..Hα-helixtrans-55.9-36173.254.80000112.4E201 V274 R275E201-S271 VanDerWaalsContact OE2-CB 3.29Å; E201-S271 WeakPolarHBondContact OE2-CB 3.44Å; E201-S271 PolarHBondContact OE2-OG 3.35Å; S271-V274 PolarHBondContact O-N 2.65Å; S271-R275 PolarHBondContact O-N 3.04Å
272E97.3Very high95.5Very high86 Ų8652.5 Ų52.540%0.40228%0.277SS..Hα-helixtrans-69.2-37.7176.3-173.956-156.900113S270 V274 R275 Q276S270-E272 PolarHBondContact O-N 3Å; E272-V274 VanDerWaalsContact C-N 3.32Å; E272-V274 PolarHBondContact O-N 2.93Å; E272-R275 WeakPolarHBondContact O-CB 3.31Å; E272-R275 PolarHBondContact O-N 3.35Å; E272-R275 IonicContact OE1-CZ 2.7Å; E272-R275 IonicContact OE1-NE 3.59Å; E272-R275 PolarHBondContact OE1-NE 3.47Å; E272-R275 IonicContact OE1-NH2 3.71Å; E272-R275 PolarHBondContact OE1-NH2 2.96Å; E272-R275 WeakPolarHBondContact OE2-CD 3.48Å; E272-R275 IonicContact OE2-NE 2.82Å; E272-R275 PolarHBondContact OE2-NE 3.47Å; E272-Q276 WeakPolarHBondContact O-CB 3.35Å; E272-Q276 PolarHBondContact O-N 2.69Å
273Q97Very high95.4Very high60 Ų6059.3 Ų59.328%0.2830%0.3SS..Hα-helixtrans-61.8-43.2173.1-176.9-175.71.400110.9W234 S270 Q276 V277W234-Q273 HydrophobicContact CH2-CG 4.35Å; W234-Q273 HydrophobicContact CZ2-CG 4.14Å; S270-Q273 WeakPolarHBondContact O-CB 3.06Å; S270-Q273 PolarHBondContact O-N 2.92Å; S270-Q273 VanDerWaalsContact O-N 3.1Å; S270-Q273 WeakPolarHBondContact OG-CB 3.24Å; S270-Q273 PolarHBondContact OG-N 3.36Å; S270-Q273 VanDerWaalsContact OG-N 3.1Å; Q273-Q276 PolarHBondContact O-N 3.16Å; Q273-V277 WeakPolarHBondContact O-CG2 3.42Å; Q273-V277 PolarHBondContact O-N 2.98Å
274V97.6Very high95.4Very high0 Ų061 Ų610%031%0.306CS..Hα-helixtrans-62-44.9175.9178.50000110.7V199 F224 W234 L238 I255 I269 S270 S271 E272 Q276 V277 V278V199-V274 HydrophobicContact CG1-CB 4.17Å; V199-V274 HydrophobicContact CG1-CG1 4.16Å; V199-V274 HydrophobicContact CG2-CB 4.29Å; V199-V274 HydrophobicContact CG2-CG1 3.8Å; F224-V274 HydrophobicContact CD2-CG2 4.32Å; F224-V274 HydrophobicContact CE2-CG1 4.03Å; F224-V274 HydrophobicContact CE2-CG2 3.74Å; F224-V274 HydrophobicContact CZ-CG1 4.43Å; F224-V274 HydrophobicContact CZ-CG2 3.88Å; W234-V274 HydrophobicContact CH2-CG2 3.96Å; W234-V274 HydrophobicContact CZ3-CG2 4.15Å; L238-V274 HydrophobicContact CD2-CG1 3.87Å; I255-V274 HydrophobicContact CD1-CG1 4.13Å; I255-V274 HydrophobicContact CG2-CG1 4.02Å; I269-V274 HydrophobicContact CG2-CG2 3.67Å; S270-V274 PolarHBondContact O-N 3.42Å; S270-V274 VanDerWaalsContact O-N 3.13Å; S271-V274 PolarHBondContact O-N 2.65Å; E272-V274 VanDerWaalsContact C-N 3.32Å; E272-V274 PolarHBondContact O-N 2.93Å; V274-Q276 VanDerWaalsContact C-N 3.34Å; V274-Q276 PolarHBondContact O-N 3.28Å; V274-V277 PolarHBondContact O-N 2.85Å; V274-V278 WeakPolarHBondContact O-CG2 3.43Å; V274-V278 PolarHBondContact O-N 3.2Å; V274-V278 VanDerWaalsContact O-N 3.1Å
275R97.7Very high95.5Very high54 Ų5459.4 Ų59.420%0.20430%0.3CS..Hα-helixtrans-55.4-49.1175.1-172.1-163.472.179.26.5111.4S271 E272 V278 H279 T286 V288S271-R275 PolarHBondContact O-N 3.04Å; E272-R275 WeakPolarHBondContact O-CB 3.31Å; E272-R275 PolarHBondContact O-N 3.35Å; E272-R275 IonicContact OE1-CZ 2.7Å; E272-R275 IonicContact OE1-NE 3.59Å; E272-R275 PolarHBondContact OE1-NE 3.47Å; E272-R275 IonicContact OE1-NH2 3.71Å; E272-R275 PolarHBondContact OE1-NH2 2.96Å; E272-R275 WeakPolarHBondContact OE2-CD 3.48Å; E272-R275 IonicContact OE2-NE 2.82Å; E272-R275 PolarHBondContact OE2-NE 3.47Å; R275-V278 PolarHBondContact O-N 2.65Å; R275-H279 WeakPolarHBondContact O-CB 3.42Å; R275-H279 PolarHBondContact O-N 3.35Å; R275-T286 HydrophobicContact CB-CG2 4.28Å; R275-T286 HydrophobicContact CG-CG2 3.79Å; R275-V288 HydrophobicContact CB-CG2 3.64Å; R275-V288 HydrophobicContact CG-CG2 4.02Å
276Q97.5Very high95.7Very high71 Ų7156.2 Ų56.233%0.33228%0.281SS..Hα-helixtrans-63.5-42.9-177.3-16862.531.600111.5E272 Q273 V274 V278 H279 D280E272-Q276 WeakPolarHBondContact O-CB 3.35Å; E272-Q276 PolarHBondContact O-N 2.69Å; Q273-Q276 PolarHBondContact O-N 3.16Å; V274-Q276 VanDerWaalsContact C-N 3.34Å; V274-Q276 PolarHBondContact O-N 3.28Å; Q276-V278 PolarHBondContact O-N 3.04Å; Q276-H279 PolarHBondContact O-N 3.23Å; Q276-D280 WeakPolarHBondContact CG-OD2 3.28Å; Q276-D280 PolarHBondContact NE2-OD1 2.93Å; Q276-D280 PolarHBondContact NE2-OD2 3.43Å; Q276-D280 VanDerWaalsContact O-CB 3.31Å; Q276-D280 WeakPolarHBondContact O-CB 3.04Å; Q276-D280 VanDerWaalsContact O-CG 3.26Å; Q276-D280 PolarHBondContact O-N 3.21Å
277V97.4Very high96.1Very high22 Ų2259.4 Ų59.413%0.13328%0.281CS..Hα-helixtrans-58.6-48.5176164.10000111.8W234 P235 Q273 V274 D280 R281W234-V277 HydrophobicContact CH2-CB 4.12Å; W234-V277 HydrophobicContact CH2-CG1 4.38Å; W234-V277 HydrophobicContact CH2-CG2 3.7Å; W234-V277 HydrophobicContact CZ2-CG2 4.36Å; W234-V277 HydrophobicContact CZ3-CB 4.25Å; W234-V277 HydrophobicContact CZ3-CG1 4.07Å; W234-V277 HydrophobicContact CZ3-CG2 4.24Å; P235-V277 HydrophobicContact CB-CG1 3.65Å; P235-V277 HydrophobicContact CB-CG2 4.25Å; P235-V277 HydrophobicContact CG-CG1 4.48Å; P235-V277 HydrophobicContact CG-CG2 4.36Å; Q273-V277 WeakPolarHBondContact O-CG2 3.42Å; Q273-V277 PolarHBondContact O-N 2.98Å; V274-V277 PolarHBondContact O-N 2.85Å; V277-D280 PolarHBondContact O-N 3.47Å; V277-R281 WeakPolarHBondContact O-CB 3.38Å; V277-R281 PolarHBondContact O-N 3.45Å
278V97.1Very high96.3Very high0 Ų055.4 Ų55.40%027%0.267CS..Hα-helixtrans-65.2-43.8-179.8176.70000110.7T197 L238 L242 I255 V274 R275 Q276 L282 R283 Y284 T286T197-V278 HydrophobicContact CG2-CG1 4.24Å; L238-V278 HydrophobicContact CD2-CG2 3.83Å; L238-V278 HydrophobicContact CG-CG2 4.48Å; L242-V278 HydrophobicContact CD1-CG1 4.07Å; L242-V278 HydrophobicContact CD1-CG2 3.66Å; I255-V278 HydrophobicContact CD1-CG2 4.13Å; V274-V278 WeakPolarHBondContact O-CG2 3.43Å; V274-V278 PolarHBondContact O-N 3.2Å; V274-V278 VanDerWaalsContact O-N 3.1Å; R275-V278 PolarHBondContact O-N 2.65Å; Q276-V278 PolarHBondContact O-N 3.04Å; V278-L282 HydrophobicContact CG1-CD1 4.44Å; V278-L282 WeakPolarHBondContact O-CA 3.46Å; V278-L282 WeakPolarHBondContact O-CB 3.44Å; V278-L282 PolarHBondContact O-N 3.43Å; V278-R283 PolarHBondContact O-N 2.87Å; V278-Y284 HydrophobicContact CG1-CD2 4.38Å; V278-T286 HydrophobicContact CB-CG2 4.34Å; V278-T286 HydrophobicContact CG1-CG2 4.34Å; V278-T286 VanDerWaalsContact CG1-OG1 3.29Å; V278-T286 WeakPolarHBondContact CG1-OG1 3.39Å
279H95.9Very high96.4Very high69 Ų6953.9 Ų53.932%0.31925%0.25SS..Hα-helixtrans-62.3-44.4177.3176.6-92.6000112.2R275 Q276 R283R275-H279 WeakPolarHBondContact O-CB 3.42Å; R275-H279 PolarHBondContact O-N 3.35Å; Q276-H279 PolarHBondContact O-N 3.23Å; H279-R283 WeakPolarHBondContact O-CA 3.32Å; H279-R283 WeakPolarHBondContact O-CD 3.5Å; H279-R283 PolarHBondContact O-N 2.98Å; H279-R283 PolarHBondContact O-NH1 3.38Å
280D96.2Very high96.4Very high69 Ų6957.5 Ų57.537%0.36927%0.273SS..Hα-helixtrans-75.9-38.6-173.1-71.1-14.8000113.3Q276 V277 R283Q276-D280 WeakPolarHBondContact CG-OD2 3.28Å; Q276-D280 PolarHBondContact NE2-OD1 2.93Å; Q276-D280 PolarHBondContact NE2-OD2 3.43Å; Q276-D280 VanDerWaalsContact O-CB 3.31Å; Q276-D280 WeakPolarHBondContact O-CB 3.04Å; Q276-D280 VanDerWaalsContact O-CG 3.26Å; Q276-D280 PolarHBondContact O-N 3.21Å; V277-D280 PolarHBondContact O-N 3.47Å; D280-R283 VanDerWaalsContact O-CZ 3.24Å; D280-R283 PolarHBondContact O-NH1 3.1Å; D280-R283 PolarHBondContact O-NH2 3.06Å; D280-R283 IonicContact OD1-NH1 3.87Å
281R96.4Very high96.4Very high124 Ų12455.4 Ų55.447%0.46826%0.257SS..Hα-helixtrans-88.7-36.1-176.5-62.5-172.1-179.1-157.31.8113.5P235 D236 C239 V277P235-R281 VanDerWaalsContact CB-CZ 3.42Å; D236-R281 IonicContact OD1-CZ 3.88Å; D236-R281 IonicContact OD1-NH1 2.76Å; D236-R281 PolarHBondContact OD1-NH1 2.97Å; D236-R281 IonicContact OD2-CZ 3.98Å; D236-R281 IonicContact OD2-NH1 3.22Å; D236-R281 PolarHBondContact OD2-NH1 2.83Å; C239-R281 HydrophobicContact CB-CB 4.47Å; V277-R281 WeakPolarHBondContact O-CB 3.38Å; V277-R281 PolarHBondContact O-N 3.45Å
282L94.9Very high96.3Very high32 Ų3256 Ų5617%0.16826%0.264CS..Hα-helixtrans-108.7-14.2-176.5-61.5179.9000114.2C239 L242 K243 V278 Y284C239-L282 HydrophobicContact CB-CD1 4.05Å; C239-L282 HydrophobicContact CB-CD2 4.06Å; C239-L282 HydrophobicContact CB-CG 3.95Å; L242-L282 HydrophobicContact CB-CD1 3.79Å; L242-L282 HydrophobicContact CD1-CD1 4.24Å; K243-L282 HydrophobicContact CB-CD2 4.09Å; V278-L282 HydrophobicContact CG1-CD1 4.44Å; V278-L282 WeakPolarHBondContact O-CA 3.46Å; V278-L282 WeakPolarHBondContact O-CB 3.44Å; V278-L282 PolarHBondContact O-N 3.43Å; L282-Y284 HydrophobicContact CB-CD1 3.92Å; L282-Y284 HydrophobicContact CB-CD2 4.07Å; L282-Y284 HydrophobicContact CB-CE1 4.04Å; L282-Y284 HydrophobicContact CB-CE2 4.19Å; L282-Y284 HydrophobicContact CB-CG 3.93Å; L282-Y284 HydrophobicContact CD1-CD2 3.93Å; L282-Y284 HydrophobicContact CD1-CE2 3.68Å; L282-Y284 VanDerWaalsContact O-CD1 3.26Å; L282-Y284 WeakPolarHBondContact O-CD1 3.48Å; L282-Y284 PolarHBondContact O-N 2.68Å
283R94.4Very high96.2Very high173 Ų17358.6 Ų58.665%0.65328%0.276SS*.  trans58.425.3-175-53.6-66.1176.3-152.6-0.1113.6V278 H279 D280V278-R283 PolarHBondContact O-N 2.87Å; H279-R283 WeakPolarHBondContact O-CA 3.32Å; H279-R283 WeakPolarHBondContact O-CD 3.5Å; H279-R283 PolarHBondContact O-N 2.98Å; H279-R283 PolarHBondContact O-NH1 3.38Å; D280-R283 VanDerWaalsContact O-CZ 3.24Å; D280-R283 PolarHBondContact O-NH1 3.1Å; D280-R283 PolarHBondContact O-NH2 3.06Å; D280-R283 IonicContact OD1-NH1 3.87Å
284Y93.9Very high96.2Very high47 Ų4759.4 Ų59.418%0.18429%0.285CS..  trans-78.2141.2175.7-66.9-5000111L242 R246 V278 L282 T286L242-Y284 HydrophobicContact CB-CE2 4.46Å; R246-Y284 HydrophobicContact CB-CE2 4.49Å; R246-Y284 WeakPolarHBondContact CB-OH 3.39Å; R246-Y284 HydrophobicContact CG-CD2 4.45Å; R246-Y284 HydrophobicContact CG-CE2 3.48Å; R246-Y284 VanDerWaalsContact CG-CE2 3.48Å; R246-Y284 VanDerWaalsContact CG-OH 3.31Å; R246-Y284 WeakPolarHBondContact CG-OH 3.38Å; V278-Y284 HydrophobicContact CG1-CD2 4.38Å; L282-Y284 HydrophobicContact CB-CD1 3.92Å; L282-Y284 HydrophobicContact CB-CD2 4.07Å; L282-Y284 HydrophobicContact CB-CE1 4.04Å; L282-Y284 HydrophobicContact CB-CE2 4.19Å; L282-Y284 HydrophobicContact CB-CG 3.93Å; L282-Y284 HydrophobicContact CD1-CD2 3.93Å; L282-Y284 HydrophobicContact CD1-CE2 3.68Å; L282-Y284 VanDerWaalsContact O-CD1 3.26Å; L282-Y284 WeakPolarHBondContact O-CD1 3.48Å; L282-Y284 PolarHBondContact O-N 2.68Å; Y284-T286 PolarHBondContact O-N 2.87Å; Y284-T286 PolarHBondContact O-OG1 2.96Å
285D94.2Very high96.1Very high61 Ų6159.6 Ų59.633%0.32629%0.286SS..  trans-67.498.5173.8-170.726.5000109.7R196 T197 R287R196-D285 HydrophobicContact CG-CB 4.12Å; R196-D285 IonicContact CZ-OD2 3.09Å; R196-D285 IonicContact NE-OD2 3.74Å; R196-D285 PolarHBondContact NE-OD2 3.43Å; R196-D285 IonicContact NH2-OD2 2.79Å; R196-D285 PolarHBondContact NH2-OD2 3.08Å; T197-D285 PolarHBondContact N-O 2.79Å; D285-R287 IonicContact OD1-CZ 2.75Å; D285-R287 IonicContact OD1-NH1 2.75Å; D285-R287 PolarHBondContact OD1-NH1 3.24Å; D285-R287 IonicContact OD1-NH2 3.36Å; D285-R287 PolarHBondContact OD1-NH2 2.85Å; D285-R287 IonicContact OD2-NH2 2.83Å; D285-R287 PolarHBondContact OD2-NH2 2.75Å
286T95.9Very high95.9Very high1 Ų158.4 Ų58.41%0.00628%0.281CS..EExtended strand (participates in β ladder)trans-112.1133.4-169.6-49.10000111T197 V199 R275 V278 Y284T197-T286 HydrophobicContact CG2-CG2 3.93Å; T197-T286 CarbonylContact O-C 3.28Å; T197-T286 VanDerWaalsContact O-CA 3.26Å; T197-T286 WeakPolarHBondContact O-CA 3.33Å; V199-T286 HydrophobicContact CG2-CG2 4.04Å; R275-T286 HydrophobicContact CB-CG2 4.28Å; R275-T286 HydrophobicContact CG-CG2 3.79Å; V278-T286 HydrophobicContact CB-CG2 4.34Å; V278-T286 HydrophobicContact CG1-CG2 4.34Å; V278-T286 VanDerWaalsContact CG1-OG1 3.29Å; V278-T286 WeakPolarHBondContact CG1-OG1 3.39Å; Y284-T286 PolarHBondContact O-N 2.87Å; Y284-T286 PolarHBondContact O-OG1 2.96Å
287R96.2Very high95.6Very high103 Ų10356.3 Ų56.339%0.38928%0.279SS..EExtended strand (participates in β ladder)trans-124.4147.6178.6-65.9-67176-77.4-11.3110.9T197 F198 V199 D285T197-R287 PolarHBondContact O-N 3.48Å; F198-R287 WeakPolarHBondContact CA-O 3.21Å; F198-R287 HydrophobicContact CD1-CB 3.86Å; F198-R287 HydrophobicContact CE1-CB 3.69Å; F198-R287 HydrophobicContact CE1-CG 4.34Å; F198-R287 HydrophobicContact CZ-CB 4.26Å; F198-R287 HydrophobicContact CZ-CG 4.49Å; V199-R287 PolarHBondContact N-O 2.85Å; D285-R287 IonicContact OD1-CZ 2.75Å; D285-R287 IonicContact OD1-NH1 2.75Å; D285-R287 PolarHBondContact OD1-NH1 3.24Å; D285-R287 IonicContact OD1-NH2 3.36Å; D285-R287 PolarHBondContact OD1-NH2 2.85Å; D285-R287 IonicContact OD2-NH2 2.83Å; D285-R287 PolarHBondContact OD2-NH2 2.75Å
288V97.4Very high95.3Very high43 Ų4357.1 Ų57.126%0.26129%0.291SS..EExtended strand (participates in β ladder)trans-101.3139.2172.11730000108.6V199 R275 V290V199-V288 HydrophobicContact CB-CG2 4.2Å; V199-V288 CarbonylContact O-C 3.52Å; V199-V288 WeakPolarHBondContact O-CA 3.35Å; R275-V288 HydrophobicContact CB-CG2 3.64Å; R275-V288 HydrophobicContact CG-CG2 4.02Å; V288-V290 HydrophobicContact CG1-CG2 3.99Å
289T96.9Very high95.2Very high40 Ų4061.3 Ų61.325%0.24532%0.316CS..EExtended strand (participates in β ladder)trans-131.3107.3171.7-58.30000108.3V199 I200 E201 L291V199-T289 PolarHBondContact O-N 3.28Å; I200-T289 WeakPolarHBondContact CA-O 3.37Å; E201-T289 PolarHBondContact N-O 3.42Å; T289-L291 HydrophobicContact CG2-CD2 4.01Å
290V97.4Very high95.3Very high84 Ų8458.1 Ų58.151%0.50930%0.302SS..EExtended strand (participates in β ladder)trans-89108.8173.2-176.30000107.7E201 V288 G292E201-V290 HydrophobicContact CB-CB 4.38Å; E201-V290 HydrophobicContact CB-CG1 4.31Å; E201-V290 HydrophobicContact CB-CG2 4.09Å; V288-V290 HydrophobicContact CG1-CG2 3.99Å; V290-G292 VanDerWaalsContact C-N 3.33Å
291L96.9Very high95.3Very high17 Ų1755 Ų559%0.08929%0.286CS..  trans-66.1-40.2-178.3-61.2-173.8000111I180 S183 I200 E201 V202 T289 V294 Q295I180-L291 HydrophobicContact CB-CD1 4.24Å; I180-L291 HydrophobicContact CG1-CD1 4.01Å; I180-L291 HydrophobicContact CG2-CD1 4.16Å; S183-L291 VanDerWaalsContact CB-CD2 3.43Å; I200-L291 HydrophobicContact CG2-CD1 3.98Å; I200-L291 HydrophobicContact CG2-CD2 4.2Å; I200-L291 HydrophobicContact CG2-CG 3.91Å; E201-L291 PolarHBondContact O-N 3.42Å; V202-L291 HydrophobicContact CG2-CD1 4.3Å; T289-L291 HydrophobicContact CG2-CD2 4.01Å; L291-V294 HydrophobicContact CB-CG2 3.96Å; L291-V294 WeakPolarHBondContact O-CG2 3.4Å; L291-Q295 HydrophobicContact CB-CG 4.06Å; L291-Q295 HydrophobicContact CD1-CG 4.34Å
292G95.1Very high95.4Very high20 Ų2049.1 Ų49.121%0.20626%0.263CS..G310 helixtrans57.7-141.5-179.900000112.4V290 V294 Q295V290-G292 VanDerWaalsContact C-N 3.33Å; G292-V294 PolarHBondContact O-N 2.79Å; G292-V294 VanDerWaalsContact O-N 3.1Å; G292-Q295 WeakPolarHBondContact O-CG 3.14Å; G292-Q295 PolarHBondContact O-N 2.78Å; G292-Q295 PolarHBondContact O-NE2 3.34Å
293H94.6Very high95.5Very high140 Ų14048.9 Ų48.965%0.64826%0.261SS*.G310 helixtrans-71.4-4.9-168.4-65.382.9000115.2Q295 R296 G297H293-Q295 PolarHBondContact O-N 3.28Å; H293-R296 PolarHBondContact O-N 2.75Å; H293-G297 PolarHBondContact O-N 3.37Å
294V95.8Very high95.7Very high78 Ų7840.6 Ų40.647%0.47323%0.23SC..G310 helixtrans-57.6-22169.3-53.30000111.7R179 L291 G292R179-V294 VanDerWaalsContact CG-O 3.28Å; R179-V294 WeakPolarHBondContact CG-O 3.46Å; L291-V294 HydrophobicContact CB-CG2 3.96Å; L291-V294 WeakPolarHBondContact O-CG2 3.4Å; G292-V294 PolarHBondContact O-N 2.79Å; G292-V294 VanDerWaalsContact O-N 3.1Å
295Q96.9Very high95.9Very high3 Ų338.5 Ų38.51%0.01422%0.222CC..G310 helixtrans-76.7-20.2176.7-61.7169.885.900113.9I160 A176 I180 M203 L291 G292 H293I160-Q295 HydrophobicContact CD1-CB 4.36Å; A176-Q295 WeakPolarHBondContact CA-O 3.35Å; A176-Q295 WeakPolarHBondContact CB-O 3.49Å; I180-Q295 HydrophobicContact CG1-CG 3.89Å; M203-Q295 VanDerWaalsContact CG-NE2 3.33Å; M203-Q295 HydrophobicContact SD-CB 4.28Å; L291-Q295 HydrophobicContact CB-CG 4.06Å; L291-Q295 HydrophobicContact CD1-CG 4.34Å; G292-Q295 WeakPolarHBondContact O-CG 3.14Å; G292-Q295 PolarHBondContact O-N 2.78Å; G292-Q295 PolarHBondContact O-NE2 3.34Å; H293-Q295 PolarHBondContact O-N 3.28Å
296R93.5Very high96Very high30 Ų3036.4 Ų36.411%0.11321%0.21CC..THydrogen-bonded Turntrans-93.9-29.9174.4-69-170.4-178.5-89.6-7.9112.4D21 S75 I160 D161 M203 H293D21-R296 PolarHBondContact O-NH1 3.15Å; S75-R296 PolarHBondContact OG-O 2.64Å; S75-R296 VanDerWaalsContact OG-O 3.04Å; I160-R296 HydrophobicContact CD1-CG 3.73Å; D161-R296 IonicContact OD2-NH2 3.04Å; M203-R296 HydrophobicContact SD-CG 4.43Å; H293-R296 PolarHBondContact O-N 2.75Å
297G91.4Very high96.1Very high27 Ų2736.4 Ų36.428%0.27821%0.21SC..  trans-83.6-172178.400000114.2H293H293-G297 PolarHBondContact O-N 3.37Å
298G90.9Very high96.2Very high38 Ų3831.5 Ų31.539%0.39219%0.192SC..SBendtrans88.2165.9175.500000114.1S75S75-G298 WeakPolarHBondContact CB-O 3.31Å; S75-G298 PolarHBondContact OG-O 2.75Å
299V94.2Very high96.2Very high88 Ų8829.5 Ų29.553%0.53318%0.179SC..PPolyproline II helixtrans-64.4128.2-177.7174.70000109.6
300P97.6Very high96.2Very high2 Ų228.6 Ų28.61%0.01317%0.171CC..PPolyproline II helixtrans-60.3140.5177.7-21.731.8000111.4A23 Q73 S175 R305A23-P300 HydrophobicContact CB-CB 4.04Å; A23-P300 HydrophobicContact CB-CG 4.03Å; Q73-P300 VanDerWaalsContact O-CD 3.28Å; Q73-P300 WeakPolarHBondContact O-CD 3.4Å; S175-P300 WeakPolarHBondContact OG-CA 3.36Å; P300-R305 HydrophobicContact CB-CG 3.93Å; P300-R305 PolarHBondContact O-NE 3.23Å; P300-R305 PolarHBondContact O-NH2 3.28Å; P300-R305 VanDerWaalsContact O-NH2 3.14Å
301S98Very high96.2Very high4 Ų424.7 Ų24.73%0.02815%0.148CC..PPolyproline II helixtrans-65.5159.617774.60000111.7D174 S175 F303 D304 R305 N550D174-S301 WeakPolarHBondContact OD2-CB 3.24Å; D174-S301 PolarHBondContact OD2-OG 3.45Å; S175-S301 PolarHBondContact OG-N 3.38Å; S301-F303 PolarHBondContact O-N 2.87Å; S301-D304 PolarHBondContact O-N 2.81Å; S301-D304 PolarHBondContact OG-N 3.18Å; S301-R305 VanDerWaalsContact O-CG 3.28Å; S301-R305 WeakPolarHBondContact O-CG 3.33Å; S301-R305 PolarHBondContact O-N 2.62Å; S301-N550 WeakPolarHBondContact CA-OD1 3.48Å; S301-N550 WeakPolarHBondContact CB-OD1 3.39Å
302A97.8Very high96.2Very high0 Ų023.9 Ų23.90%014%0.144CC..Hα-helixtrans-57-40.2175.100000111.3R305 L306 L549 N550A302-R305 PolarHBondContact O-N 3.28Å; A302-L306 WeakPolarHBondContact O-CB 3.29Å; A302-L306 WeakPolarHBondContact O-CD1 3.38Å; A302-L306 VanDerWaalsContact O-CG 3.22Å; A302-L306 WeakPolarHBondContact O-CG 3.27Å; A302-L306 PolarHBondContact O-N 2.86Å; A302-L549 HydrophobicContact CB-CB 3.73Å; A302-N550 PolarHBondContact N-OD1 2.95Å
303F97.1Very high96.3Very high27 Ų2723 Ų2312%0.11813%0.134CC..Hα-helixtrans-58.7-53.2176.4-176.5-88.8000112M169 D174 S301 R305 L306 L307 L336 F674M169-F303 HydrophobicContact CG-CE1 4.26Å; M169-F303 HydrophobicContact SD-CD1 4.01Å; M169-F303 HydrophobicContact SD-CE1 3.34Å; M169-F303 WeakPolarHBondContact SD-CE1 3.29Å; M169-F303 HydrophobicContact SD-CZ 3.87Å; D174-F303 HydrophobicContact CB-CB 4.19Å; D174-F303 HydrophobicContact CB-CD1 3.72Å; D174-F303 HydrophobicContact CB-CG 4.23Å; S301-F303 PolarHBondContact O-N 2.87Å; F303-R305 VanDerWaalsContact C-N 3.32Å; F303-R305 PolarHBondContact O-N 2.7Å; F303-L306 PolarHBondContact O-N 2.85Å; F303-L307 HydrophobicContact CE1-CB 4.31Å; F303-L307 HydrophobicContact CE1-CD2 3.82Å; F303-L307 VanDerWaalsContact O-CB 3.28Å; F303-L307 WeakPolarHBondContact O-CB 3.23Å; F303-L307 PolarHBondContact O-N 3.25Å; F303-L336 HydrophobicContact CZ-CD2 3.89Å; F303-F674 HydrophobicContact CD2-CD2 4.16Å; F303-F674 AromaticContact CD2-CE2 4Å; F303-F674 HydrophobicContact CD2-CE2 4Å; F303-F674 HydrophobicContact CE2-CD2 4.31Å; F303-F674 AromaticContact CE2-CE2 3.78Å; F303-F674 HydrophobicContact CE2-CE2 3.78Å
304D98Very high96.4Very high0 Ų016.4 Ų16.40%010%0.104CC..Hα-helixtrans-65.4-35.8-177.9-83.1-41000112.3G172 D174 S175 S301 A308G172-D304 WeakPolarHBondContact CA-OD2 3.1Å; G172-D304 PolarHBondContact N-OD1 3.4Å; G172-D304 PolarHBondContact N-OD2 3.42Å; D174-D304 PolarHBondContact N-OD2 2.94Å; S175-D304 WeakPolarHBondContact CB-OD2 3.41Å; S175-D304 PolarHBondContact N-OD2 2.67Å; S175-D304 PolarHBondContact OG-OD2 2.68Å; S301-D304 PolarHBondContact O-N 2.81Å; S301-D304 PolarHBondContact OG-N 3.18Å; D304-A308 WeakPolarHBondContact O-CB 3.22Å; D304-A308 PolarHBondContact O-N 2.79Å
305R98Very high96.4Very high3 Ų312.7 Ų12.71%0.0118%0.081CC..Hα-helixtrans-63.2-44.2174.1-66.2-179.5-155.4-163.70.3111.9I72 P300 S301 A302 F303 S309 D557 A590I72-R305 HydrophobicContact CG1-CB 4.4Å; I72-R305 HydrophobicContact CG1-CG 4.31Å; P300-R305 HydrophobicContact CB-CG 3.93Å; P300-R305 PolarHBondContact O-NE 3.23Å; P300-R305 PolarHBondContact O-NH2 3.28Å; P300-R305 VanDerWaalsContact O-NH2 3.14Å; S301-R305 VanDerWaalsContact O-CG 3.28Å; S301-R305 WeakPolarHBondContact O-CG 3.33Å; S301-R305 PolarHBondContact O-N 2.62Å; A302-R305 PolarHBondContact O-N 3.28Å; F303-R305 VanDerWaalsContact C-N 3.32Å; F303-R305 PolarHBondContact O-N 2.7Å; R305-S309 VanDerWaalsContact O-CB 3.22Å; R305-S309 WeakPolarHBondContact O-CB 3.17Å; R305-S309 PolarHBondContact O-N 2.59Å; R305-S309 PolarHBondContact O-OG 2.91Å; R305-D557 IonicContact CZ-OD2 3.52Å; R305-D557 VanDerWaalsContact CZ-OD2 3.23Å; R305-D557 IonicContact NH1-OD1 3.97Å; R305-D557 PolarHBondContact NH1-OD1 3Å; R305-D557 IonicContact NH1-OD2 2.74Å; R305-D557 PolarHBondContact NH1-OD2 3.34Å; R305-D557 IonicContact NH2-OD2 3.49Å; R305-D557 PolarHBondContact NH2-OD2 3.22Å; R305-A590 HydrophobicContact CB-CB 4.12Å; R305-A590 WeakPolarHBondContact CD-O 3.41Å
306L97Very high96.3Very high16 Ų1612.6 Ų12.68%0.0848%0.081CC..Hα-helixtrans-67.2-47.9178.2-73.4167.9000111.4A302 F303 S309 R310 L549 L586 L589 A590A302-L306 WeakPolarHBondContact O-CB 3.29Å; A302-L306 WeakPolarHBondContact O-CD1 3.38Å; A302-L306 VanDerWaalsContact O-CG 3.22Å; A302-L306 WeakPolarHBondContact O-CG 3.27Å; A302-L306 PolarHBondContact O-N 2.86Å; F303-L306 PolarHBondContact O-N 2.85Å; L306-S309 PolarHBondContact O-N 3.45Å; L306-R310 WeakPolarHBondContact O-CB 3.47Å; L306-R310 WeakPolarHBondContact O-CD 3.28Å; L306-R310 WeakPolarHBondContact O-CG 2.95Å; L306-R310 PolarHBondContact O-N 3.38Å; L306-L549 HydrophobicContact CD1-CD1 4.29Å; L306-L586 HydrophobicContact CD1-CB 4.24Å; L306-L586 HydrophobicContact CD1-CD2 3.98Å; L306-L586 HydrophobicContact CD2-CB 4.42Å; L306-L586 HydrophobicContact CD2-CD2 3.68Å; L306-L586 HydrophobicContact CG-CD2 4.46Å; L306-L589 HydrophobicContact CD2-CB 3.97Å; L306-L589 HydrophobicContact CD2-CD2 3.73Å; L306-L589 HydrophobicContact CD2-CG 3.83Å; L306-A590 HydrophobicContact CD1-CB 4.36Å; L306-A590 HydrophobicContact CD2-CB 3.88Å; L306-A590 HydrophobicContact CG-CB 3.74Å
307L97Very high96.3Very high2 Ų212.4 Ų12.41%0.018%0.082CC..Hα-helixtrans-56.8-55.4178.6179.864.3000110.1I171 F303 S309 R310 M311 L336 L341I171-L307 HydrophobicContact CG1-CD2 4.17Å; I171-L307 HydrophobicContact CG1-CG 4.31Å; F303-L307 HydrophobicContact CE1-CB 4.31Å; F303-L307 HydrophobicContact CE1-CD2 3.82Å; F303-L307 VanDerWaalsContact O-CB 3.28Å; F303-L307 WeakPolarHBondContact O-CB 3.23Å; F303-L307 PolarHBondContact O-N 3.25Å; L307-S309 PolarHBondContact O-N 2.56Å; L307-R310 PolarHBondContact O-N 3.32Å; L307-M311 HydrophobicContact CD1-CE 3.63Å; L307-M311 HydrophobicContact CD1-CG 4.26Å; L307-M311 HydrophobicContact CD1-SD 3.93Å; L307-M311 HydrophobicContact CD2-CE 4.43Å; L307-M311 HydrophobicContact CD2-SD 4.44Å; L307-M311 HydrophobicContact CG-CE 4.09Å; L307-M311 HydrophobicContact CG-CG 4.49Å; L307-M311 HydrophobicContact CG-SD 3.85Å; L307-M311 WeakPolarHBondContact O-CB 3.44Å; L307-M311 WeakPolarHBondContact O-CG 3.09Å; L307-M311 PolarHBondContact O-N 2.79Å; L307-L336 HydrophobicContact CD1-CB 4.43Å; L307-L336 HydrophobicContact CD1-CD1 3.76Å; L307-L336 HydrophobicContact CD1-CD2 4.17Å; L307-L336 HydrophobicContact CD1-CG 4.35Å; L307-L341 HydrophobicContact CD1-CD2 4.06Å
308A97.8Very high96.4Very high0 Ų011.6 Ų11.60%07%0.072CC..Hα-helixtrans-62.4-40.8-178.800000112.3G24 A27 A28 I171 D304 M311 G312G24-A308 VanDerWaalsContact O-CB 3.24Å; G24-A308 WeakPolarHBondContact O-CB 3.19Å; A27-A308 HydrophobicContact CB-CB 3.83Å; A28-A308 WeakPolarHBondContact CA-O 3.22Å; A28-A308 HydrophobicContact CB-CB 3.91Å; I171-A308 HydrophobicContact CD1-CB 3.92Å; I171-A308 HydrophobicContact CG1-CB 4.16Å; I171-A308 HydrophobicContact CG2-CB 3.91Å; D304-A308 WeakPolarHBondContact O-CB 3.22Å; D304-A308 PolarHBondContact O-N 2.79Å; A308-M311 PolarHBondContact O-N 2.98Å; A308-G312 PolarHBondContact O-N 3.32Å
309S97.4Very high96.4Very high0 Ų09.9 Ų9.90%05%0.054CC..Hα-helixtrans-64.6-41.9177.4-61.10000112.1A31 R305 L306 L307 A313A31-S309 WeakPolarHBondContact CB-O 3.43Å; R305-S309 VanDerWaalsContact O-CB 3.22Å; R305-S309 WeakPolarHBondContact O-CB 3.17Å; R305-S309 PolarHBondContact O-N 2.59Å; R305-S309 PolarHBondContact O-OG 2.91Å; L306-S309 PolarHBondContact O-N 3.45Å; L307-S309 PolarHBondContact O-N 2.56Å; S309-A313 PolarHBondContact O-N 3.1Å; S309-A313 VanDerWaalsContact O-N 3.15Å
310R97Very high96.2Very high21 Ų218.7 Ų8.78%0.0794%0.044CC..Hα-helixtrans-68.7-43.3177.7-67.7165.161-162.2-1111L306 L307 A313 D314 N339 L341 L749 L752L306-R310 WeakPolarHBondContact O-CB 3.47Å; L306-R310 WeakPolarHBondContact O-CD 3.28Å; L306-R310 WeakPolarHBondContact O-CG 2.95Å; L306-R310 PolarHBondContact O-N 3.38Å; L307-R310 PolarHBondContact O-N 3.32Å; R310-A313 PolarHBondContact O-N 3.05Å; R310-D314 PolarHBondContact O-N 3.4Å; R310-N339 PolarHBondContact NH2-O 2.8Å; R310-L341 HydrophobicContact CB-CD1 3.55Å; R310-L341 HydrophobicContact CB-CG 4.49Å; R310-L749 HydrophobicContact CG-CD2 4.15Å; R310-L752 HydrophobicContact CG-CD2 4.2Å
311M97.6Very high95.6Very high3 Ų313.1 Ų13.12%0.0157%0.067CC..Hα-helixtrans-62.8-43.1177.3-79-178.6163.100111.9L156 I171 L307 A308 A313 D314 A315 I334 L336 L341L156-M311 HydrophobicContact CD2-CB 3.87Å; I171-M311 HydrophobicContact CD1-SD 3.81Å; I171-M311 HydrophobicContact CG1-SD 3.83Å; L307-M311 HydrophobicContact CD1-CE 3.63Å; L307-M311 HydrophobicContact CD1-CG 4.26Å; L307-M311 HydrophobicContact CD1-SD 3.93Å; L307-M311 HydrophobicContact CD2-CE 4.43Å; L307-M311 HydrophobicContact CD2-SD 4.44Å; L307-M311 HydrophobicContact CG-CE 4.09Å; L307-M311 HydrophobicContact CG-CG 4.49Å; L307-M311 HydrophobicContact CG-SD 3.85Å; L307-M311 WeakPolarHBondContact O-CB 3.44Å; L307-M311 WeakPolarHBondContact O-CG 3.09Å; L307-M311 PolarHBondContact O-N 2.79Å; A308-M311 PolarHBondContact O-N 2.98Å; M311-A313 PolarHBondContact O-N 3.04Å; M311-D314 PolarHBondContact O-N 2.93Å; M311-A315 WeakPolarHBondContact O-CB 3.19Å; M311-A315 PolarHBondContact O-N 2.92Å; M311-I334 HydrophobicContact CB-CG2 4.27Å; M311-I334 HydrophobicContact CG-CB 4.43Å; M311-I334 HydrophobicContact CG-CG2 3.91Å; M311-L336 HydrophobicContact CE-CB 4.3Å; M311-L341 HydrophobicContact CE-CD2 3.95Å; M311-L341 HydrophobicContact CG-CD1 4.26Å; M311-L341 HydrophobicContact CG-CD2 3.67Å
312G97.6Very high94.7Very high0 Ų013.7 Ų13.70%07%0.072CC..Hα-helixtrans-63.9-39.2176.800000113.1A308 A315 V316A308-G312 PolarHBondContact O-N 3.32Å; G312-A315 PolarHBondContact O-N 2.99Å; G312-V316 PolarHBondContact O-N 3.06Å
313A96.9Very high92.9Very high0 Ų022.8 Ų22.80%011%0.112CC..Hα-helixtrans-65.2-45.6173.900000112V35 S309 R310 M311 A315 V316 L317 L752 Y763V35-A313 HydrophobicContact CG2-CB 3.9Å; S309-A313 PolarHBondContact O-N 3.1Å; S309-A313 VanDerWaalsContact O-N 3.15Å; R310-A313 PolarHBondContact O-N 3.05Å; M311-A313 PolarHBondContact O-N 3.04Å; A313-A315 VanDerWaalsContact C-N 3.3Å; A313-A315 PolarHBondContact O-N 2.8Å; A313-V316 PolarHBondContact O-N 3.11Å; A313-L317 WeakPolarHBondContact O-CG 3.32Å; A313-L317 PolarHBondContact O-N 2.76Å; A313-L752 HydrophobicContact CB-CD1 3.66Å; A313-L752 HydrophobicContact CB-CD2 4.36Å; A313-Y763 HydrophobicContact CB-CD1 4.44Å; A313-Y763 HydrophobicContact CB-CE1 4.04Å
314D96.1Very high90.8Very high3 Ų329 Ų292%0.01614%0.139CC..Hα-helixtrans-67.2-30.5178.7-167.943.8000112.5R310 M311 V316 L317 A318 I334 L341 R343 T765R310-D314 PolarHBondContact O-N 3.4Å; M311-D314 PolarHBondContact O-N 2.93Å; D314-V316 PolarHBondContact O-N 3.15Å; D314-L317 PolarHBondContact O-N 2.59Å; D314-A318 WeakPolarHBondContact O-CB 3.25Å; D314-A318 PolarHBondContact O-N 2.82Å; D314-I334 HydrophobicContact CB-CG2 4.25Å; D314-L341 HydrophobicContact CB-CD1 4.3Å; D314-R343 IonicContact OD1-CZ 2.7Å; D314-R343 IonicContact OD1-NE 2.67Å; D314-R343 PolarHBondContact OD1-NE 3.19Å; D314-R343 VanDerWaalsContact OD1-NE 3.15Å; D314-R343 IonicContact OD1-NH2 3.13Å; D314-R343 PolarHBondContact OD1-NH2 2.55Å; D314-R343 IonicContact OD2-NE 2.86Å; D314-R343 PolarHBondContact OD2-NE 2.94Å; D314-T765 HydrophobicContact CB-CG2 4.11Å; D314-T765 WeakPolarHBondContact OD1-CG2 3.46Å
315A96.8Very high88.6Confident0 Ų029.7 Ų29.70%014%0.144CC..Hα-helixtrans-62.6-41.8175.100000112.5V109 V154 L156 M311 G312 A313 A318 L319 I334V109-A315 HydrophobicContact CG1-CB 4.27Å; V109-A315 HydrophobicContact CG2-CB 4.5Å; V154-A315 HydrophobicContact CB-CB 4.34Å; V154-A315 HydrophobicContact CG1-CB 3.64Å; L156-A315 HydrophobicContact CD1-CB 4.25Å; L156-A315 HydrophobicContact CD2-CB 4.06Å; L156-A315 HydrophobicContact CG-CB 4.34Å; M311-A315 WeakPolarHBondContact O-CB 3.19Å; M311-A315 PolarHBondContact O-N 2.92Å; G312-A315 PolarHBondContact O-N 2.99Å; A313-A315 VanDerWaalsContact C-N 3.3Å; A313-A315 PolarHBondContact O-N 2.8Å; A315-A318 PolarHBondContact O-N 3.22Å; A315-L319 WeakPolarHBondContact O-CG 3.19Å; A315-L319 PolarHBondContact O-N 3.17Å; A315-L319 VanDerWaalsContact O-N 3.15Å; A315-I334 HydrophobicContact CB-CG1 4.17Å
316V95.7Very high86.1Confident0 Ų032.8 Ų32.80%016%0.163CC..Hα-helixtrans-65.8-44.6175.71760000110.5M13 V32 V35 G312 A313 D314 A318 L319 M320M13-V316 HydrophobicContact CE-CB 4.47Å; M13-V316 HydrophobicContact CE-CG1 4.11Å; M13-V316 HydrophobicContact CE-CG2 4.18Å; M13-V316 HydrophobicContact SD-CG2 4.19Å; V32-V316 HydrophobicContact CB-CG2 4.37Å; V32-V316 HydrophobicContact CG1-CG2 4.04Å; V32-V316 WeakPolarHBondContact O-CG2 3.46Å; V35-V316 HydrophobicContact CB-CB 4.29Å; V35-V316 HydrophobicContact CB-CG1 4.46Å; V35-V316 HydrophobicContact CB-CG2 4.19Å; V35-V316 HydrophobicContact CG1-CB 3.83Å; V35-V316 HydrophobicContact CG1-CG1 3.83Å; V35-V316 HydrophobicContact CG1-CG2 4.28Å; G312-V316 PolarHBondContact O-N 3.06Å; A313-V316 PolarHBondContact O-N 3.11Å; D314-V316 PolarHBondContact O-N 3.15Å; V316-A318 VanDerWaalsContact C-N 3.32Å; V316-A318 PolarHBondContact O-N 2.81Å; V316-L319 PolarHBondContact O-N 3.44Å; V316-M320 HydrophobicContact CG1-SD 4.16Å; V316-M320 WeakPolarHBondContact O-CG 3.47Å; V316-M320 PolarHBondContact O-N 2.92Å
317L93.2Very high83.8Confident27 Ų2740.5 Ų40.514%0.14121%0.205CC..Hα-helixtrans-63.3-39.4178.3-65.6173.2000111.7A313 D314 L319 M320 D321 Y763 T765A313-L317 WeakPolarHBondContact O-CG 3.32Å; A313-L317 PolarHBondContact O-N 2.76Å; D314-L317 PolarHBondContact O-N 2.59Å; L317-L319 VanDerWaalsContact C-N 3.32Å; L317-L319 PolarHBondContact O-N 3.41Å; L317-M320 HydrophobicContact CD2-SD 4.25Å; L317-M320 WeakPolarHBondContact O-CB 2.98Å; L317-M320 PolarHBondContact O-N 2.85Å; L317-M320 VanDerWaalsContact O-N 3.14Å; L317-D321 WeakPolarHBondContact O-CB 3.48Å; L317-D321 PolarHBondContact O-N 2.95Å; L317-Y763 HydrophobicContact CD1-CD1 3.92Å; L317-Y763 HydrophobicContact CD1-CE1 4.13Å; L317-T765 HydrophobicContact CB-CG2 4.49Å; L317-T765 HydrophobicContact CD1-CG2 3.3Å
318A92.8Very high81.6Confident9 Ų948.9 Ų48.97%0.07424%0.244CC..Hα-helixtrans-60.4-39.3174.200000112.7V154 D314 A315 V316 M320 A322 V332 I334V154-A318 HydrophobicContact CG2-CB 4.09Å; D314-A318 WeakPolarHBondContact O-CB 3.25Å; D314-A318 PolarHBondContact O-N 2.82Å; A315-A318 PolarHBondContact O-N 3.22Å; V316-A318 VanDerWaalsContact C-N 3.32Å; V316-A318 PolarHBondContact O-N 2.81Å; A318-M320 VanDerWaalsContact C-N 3.35Å; A318-A322 PolarHBondContact O-N 3.11Å; A318-V332 HydrophobicContact CB-CG2 4.05Å; A318-I334 HydrophobicContact CB-CD1 4.26Å
319L91.8Very high79.9Confident2 Ų251.8 Ų51.81%0.0126%0.259CS..Hα-helixtrans-68.9-32.5175.1-70.7167.2000112.8M13 D107 V109 R152 V154 A315 V316 L317M13-L319 HydrophobicContact CE-CB 4.42Å; M13-L319 HydrophobicContact CE-CD1 3.6Å; M13-L319 HydrophobicContact SD-CD1 4.12Å; D107-L319 HydrophobicContact CB-CD1 4.15Å; D107-L319 HydrophobicContact CB-CD2 4.33Å; V109-L319 HydrophobicContact CG2-CD1 3.46Å; V109-L319 VanDerWaalsContact CG2-CD1 3.46Å; R152-L319 HydrophobicContact CB-CD2 3.87Å; R152-L319 PolarHBondContact NH1-O 3.38Å; V154-L319 HydrophobicContact CB-CG 4.4Å; V154-L319 HydrophobicContact CG2-CD1 4.31Å; V154-L319 HydrophobicContact CG2-CD2 3.66Å; V154-L319 HydrophobicContact CG2-CG 3.6Å; A315-L319 WeakPolarHBondContact O-CG 3.19Å; A315-L319 PolarHBondContact O-N 3.17Å; A315-L319 VanDerWaalsContact O-N 3.15Å; V316-L319 PolarHBondContact O-N 3.44Å; L317-L319 VanDerWaalsContact C-N 3.32Å; L317-L319 PolarHBondContact O-N 3.41Å
320M88.4Confident79.1Confident64 Ų6455.6 Ų55.632%0.31528%0.277SS..Hα-helixtrans-71.7-42.1175.4-69.8176.267.500112.3N39 Y41 V316 L317 A318 A322N39-M320 HydrophobicContact CB-CE 3.87Å; N39-M320 HydrophobicContact CB-SD 3.59Å; N39-M320 VanDerWaalsContact CB-SD 3.59Å; N39-M320 VanDerWaalsContact CG-SD 3.51Å; N39-M320 WeakPolarHBondContact OD1-CE 3.49Å; Y41-M320 HydrophobicContact CE2-CG 3.75Å; Y41-M320 HydrophobicContact CE2-SD 4.34Å; V316-M320 HydrophobicContact CG1-SD 4.16Å; V316-M320 WeakPolarHBondContact O-CG 3.47Å; V316-M320 PolarHBondContact O-N 2.92Å; L317-M320 HydrophobicContact CD2-SD 4.25Å; L317-M320 WeakPolarHBondContact O-CB 2.98Å; L317-M320 PolarHBondContact O-N 2.85Å; L317-M320 VanDerWaalsContact O-N 3.14Å; A318-M320 VanDerWaalsContact C-N 3.35Å; M320-A322 PolarHBondContact O-N 3.23Å
321D85.8Confident78.8Confident94 Ų9454.9 Ų54.950%0.50328%0.276SS..Hα-helixtrans-66.9-26.4178.8-67.3-24.6000112L317 K323 R343L317-D321 WeakPolarHBondContact O-CB 3.48Å; L317-D321 PolarHBondContact O-N 2.95Å; D321-K323 PolarHBondContact O-N 3.36Å; D321-R343 IonicContact OD2-CZ 3.28Å; D321-R343 IonicContact OD2-NH1 3.09Å; D321-R343 PolarHBondContact OD2-NH1 3.26Å; D321-R343 IonicContact OD2-NH2 3.2Å; D321-R343 PolarHBondContact OD2-NH2 3.44Å
322A78.2Confident78.6Confident17 Ų1756.4 Ų56.414%0.1429%0.285CS..  trans-66.589.7175.100000110.9A318 M320 K324A318-A322 PolarHBondContact O-N 3.11Å; M320-A322 PolarHBondContact O-N 3.23Å; A322-K324 PolarHBondContact O-N 3.05Å
323K60.4Low78.5Confident190 Ų19056.4 Ų56.483%0.82629%0.285SS*.  trans-61.7-38.2-175.7-72.5-176.3178.8177.70114D321D321-K323 PolarHBondContact O-N 3.36Å
324K53.7Low78.5Confident159 Ų15956.4 Ų56.469%0.69129%0.285SS*.SBendtrans-159.4138.4170.9-75.8-171176.6176.40108.4A322 T326 N329A322-K324 PolarHBondContact O-N 3.05Å; K324-T326 HydrophobicContact CB-CG2 4.24Å; K324-T326 PolarHBondContact O-N 3.23Å; K324-N329 PolarHBondContact O-ND2 3.32Å
325A50.8Low78.5Confident14 Ų1456.3 Ų56.312%0.11628%0.284CS..  trans-64.4107.416500000107.4E150 R152E150-A325 HydrophobicContact CB-CB 3.74Å; E150-A325 WeakPolarHBondContact OE2-CB 3.14Å; E150-A325 VanDerWaalsContact OE2-O 3.1Å; R152-A325 HydrophobicContact CG-CB 4.27Å
326T46.8Very low78.3Confident67 Ų6756.5 Ų56.541%0.41129%0.285SS..SBendtrans-122.4169.8166.451.50000105.3K324 E328 N329K324-T326 HydrophobicContact CB-CG2 4.24Å; K324-T326 PolarHBondContact O-N 3.23Å; T326-E328 PolarHBondContact O-N 3.31Å; T326-N329 PolarHBondContact O-N 2.98Å
327D47.5Very low78Confident179 Ų17958.1 Ų58.196%0.95729%0.294SS*.THydrogen-bonded Turntrans-55-17.6174.5-79.5-33.2000113.3
328E51.6Low77.5Confident178 Ų17857.5 Ų57.583%0.83229%0.294SS*.THydrogen-bonded Turntrans-77.4-23.9172.7-63.8-176.6161.200114T326 E330T326-E328 PolarHBondContact O-N 3.31Å; E328-E330 PolarHBondContact O-N 3.49Å
329N62.9Low77Confident60 Ų6058.4 Ų58.432%0.32130%0.298SS..SBendtrans-94.671.3178.6-86.9-23.3000110.9R124 K324 T326R124-N329 PolarHBondContact NH2-O 3.22Å; K324-N329 PolarHBondContact O-ND2 3.32Å; T326-N329 PolarHBondContact O-N 2.98Å
330E80.4Confident76.9Confident80 Ų8059.6 Ų59.637%0.37431%0.305SS..  trans-52.7136.8171.2-165.5169.3-165.300110.2E328 V332 S345 K348E328-E330 PolarHBondContact O-N 3.49Å; E330-V332 WeakPolarHBondContact O-CG1 3.12Å; E330-V332 PolarHBondContact O-N 3.29Å; E330-S345 WeakPolarHBondContact OE1-CB 3.42Å; E330-S345 PolarHBondContact OE1-OG 3.02Å; E330-S345 WeakPolarHBondContact OE2-CB 3.31Å; E330-K348 IonicContact OE1-NZ 3.33Å; E330-K348 IonicContact OE2-NZ 3.59Å; E330-K348 PolarHBondContact OE2-NZ 3.34Å
331P89.9Confident77.1Confident7 Ų756.9 Ų56.95%0.04529%0.291CS..  trans-66.7137.7-178.328.6-26.9000108.5R124 I153 L346R124-P331 VanDerWaalsContact NH1-CG 3.28Å; I153-P331 HydrophobicContact CD1-CB 3.63Å; I153-P331 HydrophobicContact CD1-CG 4.43Å; I153-P331 HydrophobicContact CG1-CB 3.51Å; P331-L346 HydrophobicContact CB-CB 4.24Å; P331-L346 HydrophobicContact CB-CD2 4.31Å; P331-L346 HydrophobicContact CG-CB 4.21Å; P331-L346 WeakPolarHBondContact O-CB 3.42Å; P331-L346 PolarHBondContact O-N 3.02Å
332V93.6Very high77.4Confident35 Ų3553.4 Ų53.421%0.21227%0.274CS..EExtended strand (participates in β ladder)trans-107.7147.6-173.8-58.70000112.3V154 G155 A318 E330 I334 R343 R344V154-V332 WeakPolarHBondContact CA-O 3.31Å; V154-V332 HydrophobicContact CG1-CG2 4.27Å; V154-V332 HydrophobicContact CG2-CG2 3.74Å; G155-V332 PolarHBondContact N-O 2.7Å; A318-V332 HydrophobicContact CB-CG2 4.05Å; E330-V332 WeakPolarHBondContact O-CG1 3.12Å; E330-V332 PolarHBondContact O-N 3.29Å; V332-I334 HydrophobicContact CG2-CD1 4.44Å; V332-R343 HydrophobicContact CB-CB 4.48Å; V332-R344 CarbonylContact C-O 3.43Å; V332-R344 VanDerWaalsContact CA-O 3.22Å; V332-R344 WeakPolarHBondContact CA-O 3.32Å
333V96.2Very high78.2Confident0 Ų055.9 Ų55.90%028%0.28CS..EExtended strand (participates in β ladder)trans-114.1133.2164.356.90000107.7L117 G155 V157 F164 T335 R344 L346 C349L117-V333 HydrophobicContact CD1-CG2 4.16Å; G155-V333 VanDerWaalsContact O-CA 3.31Å; G155-V333 WeakPolarHBondContact O-CA 3.26Å; G155-V333 WeakPolarHBondContact O-CG2 3.42Å; V157-V333 HydrophobicContact CG2-CG2 3.63Å; F164-V333 HydrophobicContact CE1-CG1 4.16Å; F164-V333 HydrophobicContact CE1-CG2 4.02Å; F164-V333 HydrophobicContact CZ-CG2 4.44Å; V333-T335 HydrophobicContact CB-CG2 4.45Å; V333-T335 HydrophobicContact CG1-CG2 3.85Å; V333-T335 HydrophobicContact CG2-CG2 4.02Å; V333-R344 HydrophobicContact CG1-CB 4.2Å; V333-R344 PolarHBondContact N-O 3.35Å; V333-R344 PolarHBondContact O-N 2.97Å; V333-L346 HydrophobicContact CB-CB 4.36Å; V333-L346 HydrophobicContact CB-CD1 4.28Å; V333-L346 HydrophobicContact CG1-CB 4.45Å; V333-C349 HydrophobicContact CG1-CB 4.26Å
334I97.1Very high79.8Confident0 Ų051.1 Ų51.10%026%0.256CS..EExtended strand (participates in β ladder)trans-83.6118.7175.3-43.9-57.3000107.5V154 G155 L156 M311 D314 A315 A318 V332 L341 R343V154-I334 HydrophobicContact CG1-CD1 3.93Å; V154-I334 HydrophobicContact CG1-CG1 3.76Å; G155-I334 PolarHBondContact O-N 3.1Å; L156-I334 HydrophobicContact CD2-CB 3.59Å; L156-I334 HydrophobicContact CD2-CG1 3.55Å; M311-I334 HydrophobicContact CB-CG2 4.27Å; M311-I334 HydrophobicContact CG-CB 4.43Å; M311-I334 HydrophobicContact CG-CG2 3.91Å; D314-I334 HydrophobicContact CB-CG2 4.25Å; A315-I334 HydrophobicContact CB-CG1 4.17Å; A318-I334 HydrophobicContact CB-CD1 4.26Å; V332-I334 HydrophobicContact CG2-CD1 4.44Å; I334-L341 HydrophobicContact CG2-CD1 4.43Å; I334-R343 HydrophobicContact CD1-CG 3.83Å
335T95Very high81.7Confident0 Ų044.2 Ų44.20%023%0.228CC..EExtended strand (participates in β ladder)trans-122.7169.9-176.6730000112G166 V333 L341 V342 R344G166-T335 VanDerWaalsContact O-CB 3.29Å; G166-T335 WeakPolarHBondContact O-CB 3.23Å; G166-T335 PolarHBondContact O-OG1 3.17Å; V333-T335 HydrophobicContact CB-CG2 4.45Å; V333-T335 HydrophobicContact CG1-CG2 3.85Å; V333-T335 HydrophobicContact CG2-CG2 4.02Å; T335-L341 WeakPolarHBondContact O-CA 3.15Å; T335-V342 PolarHBondContact N-O 2.9Å; T335-V342 PolarHBondContact O-N 3.32Å; T335-V342 PolarHBondContact OG1-O 3.09Å; T335-R344 HydrophobicContact CG2-CB 4.41Å; T335-R344 WeakPolarHBondContact OG1-CD 3.33Å; T335-R344 PolarHBondContact OG1-NE 2.84Å
336L92.7Very high83.7Confident4 Ų443.6 Ų43.62%0.02122%0.223CC..EExtended strand (participates in β ladder)trans-106.8128.3173.8-164.470.5000109.7T167 D168 M169 F303 L307 M311 L341T167-L336 WeakPolarHBondContact CA-O 3.27Å; T167-L336 PolarHBondContact OG1-N 3.07Å; D168-L336 PolarHBondContact N-O 3.45Å; M169-L336 HydrophobicContact CB-CD2 4.13Å; F303-L336 HydrophobicContact CZ-CD2 3.89Å; L307-L336 HydrophobicContact CD1-CB 4.43Å; L307-L336 HydrophobicContact CD1-CD1 3.76Å; L307-L336 HydrophobicContact CD1-CD2 4.17Å; L307-L336 HydrophobicContact CD1-CG 4.35Å; M311-L336 HydrophobicContact CE-CB 4.3Å; L336-L341 HydrophobicContact CD1-CD2 3.96Å
337D89Confident85.8Confident35 Ų3541.6 Ų41.619%0.18721%0.211CC..EExtended strand (participates in β ladder)trans-131.3107.2171.6-177.1-0.4000108D168 N339 V340 V342 R344 R720D168-D337 WeakPolarHBondContact OD2-CA 3.09Å; D337-N339 PolarHBondContact O-N 3.17Å; D337-V340 PolarHBondContact N-O 3.46Å; D337-V340 PolarHBondContact O-N 2.9Å; D337-V340 VanDerWaalsContact O-N 3.09Å; D337-V342 HydrophobicContact CB-CG2 3.74Å; D337-R344 IonicContact OD2-NH2 2.73Å; D337-R344 PolarHBondContact OD2-NH2 3.07Å; D337-R344 VanDerWaalsContact OD2-NH2 3.1Å; D337-R720 WeakPolarHBondContact O-CG 3.46Å; D337-R720 IonicContact OD2-CZ 3.53Å; D337-R720 IonicContact OD2-NE 3.37Å; D337-R720 IonicContact OD2-NH1 2.75Å; D337-R720 PolarHBondContact OD2-NH1 3.37Å
338G83.2Confident88Confident13 Ų1338.3 Ų38.313%0.13419%0.188CC..THydrogen-bonded Turntrans45.260.6-172.600000112.8D168 V340 H719D168-G338 PolarHBondContact OD2-N 3.38Å; G338-V340 PolarHBondContact O-N 3.41Å; G338-H719 CarbonylContact O-C 3.54Å
339N83.1Confident90Very high29 Ų2930 Ų3016%0.15515%0.15CC..THydrogen-bonded Turntrans62.50.3179.4-64.1-23.5000116.8R310 D337 Y541R310-N339 PolarHBondContact NH2-O 2.8Å; D337-N339 PolarHBondContact O-N 3.17Å; N339-Y541 HydrophobicContact CB-CE2 3.65Å; N339-Y541 VanDerWaalsContact ND2-CE2 3.33Å; N339-Y541 WeakPolarHBondContact ND2-CE2 3.28Å
340V88.5Confident91.4Very high26 Ų2627.6 Ų27.616%0.15814%0.137CC..EExtended strand (participates in β ladder)trans-97.3136.7172.5-175.50000108.9D337 G338 H719 R720D337-V340 PolarHBondContact N-O 3.46Å; D337-V340 PolarHBondContact O-N 2.9Å; D337-V340 VanDerWaalsContact O-N 3.09Å; G338-V340 PolarHBondContact O-N 3.41Å; V340-H719 HydrophobicContact CG2-CB 4.34Å; V340-R720 HydrophobicContact CG2-CG 4.33Å
341L92.8Very high91.9Very high7 Ų728.8 Ų28.84%0.03714%0.142CC..EExtended strand (participates in β ladder)trans-74.6134.4173-67.1-171.4000109.8L307 R310 M311 D314 I334 T335 L336L307-L341 HydrophobicContact CD1-CD2 4.06Å; R310-L341 HydrophobicContact CB-CD1 3.55Å; R310-L341 HydrophobicContact CB-CG 4.49Å; M311-L341 HydrophobicContact CE-CD2 3.95Å; M311-L341 HydrophobicContact CG-CD1 4.26Å; M311-L341 HydrophobicContact CG-CD2 3.67Å; D314-L341 HydrophobicContact CB-CD1 4.3Å; I334-L341 HydrophobicContact CG2-CD1 4.43Å; T335-L341 WeakPolarHBondContact O-CA 3.15Å; L336-L341 HydrophobicContact CD1-CD2 3.96Å
342V92.9Very high92.1Very high22 Ų2232.4 Ų32.413%0.13316%0.159CC..EExtended strand (participates in β ladder)trans-134.5136.4179.4-172.30000108.8T335 D337 R344T335-V342 PolarHBondContact N-O 2.9Å; T335-V342 PolarHBondContact O-N 3.32Å; T335-V342 PolarHBondContact OG1-O 3.09Å; D337-V342 HydrophobicContact CB-CG2 3.74Å; V342-R344 HydrophobicContact CG1-CG 4.27Å
343R94.2Very high92Very high69 Ų6931.1 Ų31.126%0.2615%0.151SC..EExtended strand (participates in β ladder)trans-85.6122.6171.3-54.9-177.9-174.4168.8-0.2108D314 D321 V332 I334D314-R343 IonicContact OD1-CZ 2.7Å; D314-R343 IonicContact OD1-NE 2.67Å; D314-R343 PolarHBondContact OD1-NE 3.19Å; D314-R343 VanDerWaalsContact OD1-NE 3.15Å; D314-R343 IonicContact OD1-NH2 3.13Å; D314-R343 PolarHBondContact OD1-NH2 2.55Å; D314-R343 IonicContact OD2-NE 2.86Å; D314-R343 PolarHBondContact OD2-NE 2.94Å; D321-R343 IonicContact OD2-CZ 3.28Å; D321-R343 IonicContact OD2-NH1 3.09Å; D321-R343 PolarHBondContact OD2-NH1 3.26Å; D321-R343 IonicContact OD2-NH2 3.2Å; D321-R343 PolarHBondContact OD2-NH2 3.44Å; V332-R343 HydrophobicContact CB-CB 4.48Å; I334-R343 HydrophobicContact CD1-CG 3.83Å
344R93.2Very high91.8Very high89 Ų8935.4 Ų35.434%0.33617%0.173SC..EExtended strand (participates in β ladder)trans-120.9157.2177.4-67.6-171.9-179.8-109.9-0.6110.6G166 V332 V333 T335 D337 V342 L346G166-R344 WeakPolarHBondContact O-CD 3.28Å; G166-R344 PolarHBondContact O-NE 3.39Å; G166-R344 VanDerWaalsContact O-NE 3.1Å; V332-R344 CarbonylContact C-O 3.43Å; V332-R344 VanDerWaalsContact CA-O 3.22Å; V332-R344 WeakPolarHBondContact CA-O 3.32Å; V333-R344 HydrophobicContact CG1-CB 4.2Å; V333-R344 PolarHBondContact N-O 3.35Å; V333-R344 PolarHBondContact O-N 2.97Å; T335-R344 HydrophobicContact CG2-CB 4.41Å; T335-R344 WeakPolarHBondContact OG1-CD 3.33Å; T335-R344 PolarHBondContact OG1-NE 2.84Å; D337-R344 IonicContact OD2-NH2 2.73Å; D337-R344 PolarHBondContact OD2-NH2 3.07Å; D337-R344 VanDerWaalsContact OD2-NH2 3.1Å; V342-R344 HydrophobicContact CG1-CG 4.27Å; R344-L346 PolarHBondContact O-N 3.15Å
345S93.7Very high91.6Very high15 Ų1539.6 Ų39.611%0.10519%0.193CC..EExtended strand (participates in β ladder)trans-58.4121.8169.2165.70000110.3E330 T347 K348 C349E330-S345 WeakPolarHBondContact OE1-CB 3.42Å; E330-S345 PolarHBondContact OE1-OG 3.02Å; E330-S345 WeakPolarHBondContact OE2-CB 3.31Å; S345-T347 VanDerWaalsContact C-N 3.32Å; S345-T347 PolarHBondContact OG-N 2.91Å; S345-K348 WeakPolarHBondContact OG-CG 3.34Å; S345-K348 PolarHBondContact OG-N 3.39Å; S345-C349 PolarHBondContact O-N 3.42Å; S345-C349 PolarHBondContact O-SG 3.16Å
346L93.6Very high91.5Very high0 Ų039.7 Ų39.70%019%0.193CC..Hα-helixtrans-60.6-44.9172.6170.560.2000110.4L117 L120 N121 I153 F164 P331 V333 R344 K348 C349 V350L117-L346 HydrophobicContact CB-CD1 3.83Å; L117-L346 HydrophobicContact CD1-CD1 4.41Å; L120-L346 HydrophobicContact CD2-CD2 4.33Å; N121-L346 HydrophobicContact CB-CD2 4.04Å; N121-L346 HydrophobicContact CB-CG 4.36Å; I153-L346 HydrophobicContact CD1-CD2 3.78Å; F164-L346 HydrophobicContact CZ-CD1 4.2Å; P331-L346 HydrophobicContact CB-CB 4.24Å; P331-L346 HydrophobicContact CB-CD2 4.31Å; P331-L346 HydrophobicContact CG-CB 4.21Å; P331-L346 WeakPolarHBondContact O-CB 3.42Å; P331-L346 PolarHBondContact O-N 3.02Å; V333-L346 HydrophobicContact CB-CB 4.36Å; V333-L346 HydrophobicContact CB-CD1 4.28Å; V333-L346 HydrophobicContact CG1-CB 4.45Å; R344-L346 PolarHBondContact O-N 3.15Å; L346-K348 PolarHBondContact O-N 2.9Å; L346-C349 PolarHBondContact O-N 2.7Å; L346-V350 HydrophobicContact CD1-CG2 3.84Å; L346-V350 HydrophobicContact CG-CG2 4.43Å; L346-V350 VanDerWaalsContact O-CG2 3.31Å; L346-V350 WeakPolarHBondContact O-CG2 3.16Å; L346-V350 PolarHBondContact O-N 3.09Å
347T91.5Very high91.5Very high26 Ų2643 Ų4316%0.1621%0.208CC..Hα-helixtrans-57.1-52-179-50.20000111.5S345 C349 V350 E351S345-T347 VanDerWaalsContact C-N 3.32Å; S345-T347 PolarHBondContact OG-N 2.91Å; T347-C349 VanDerWaalsContact C-N 3.33Å; T347-C349 PolarHBondContact O-N 2.82Å; T347-V350 PolarHBondContact O-N 3.45Å; T347-E351 WeakPolarHBondContact O-CG 3.31Å; T347-E351 PolarHBondContact O-N 3Å
348K93.2Very high91.8Very high110 Ų11044.1 Ų44.148%0.47822%0.222SC..Hα-helixtrans-63.6-38.5-179-66.9173.2-174.5147.60112.2E330 S345 L346 E351 Q352E330-K348 IonicContact OE1-NZ 3.33Å; E330-K348 IonicContact OE2-NZ 3.59Å; E330-K348 PolarHBondContact OE2-NZ 3.34Å; S345-K348 WeakPolarHBondContact OG-CG 3.34Å; S345-K348 PolarHBondContact OG-N 3.39Å; L346-K348 PolarHBondContact O-N 2.9Å; K348-E351 PolarHBondContact O-N 3.2Å; K348-Q352 WeakPolarHBondContact O-CG 3.21Å; K348-Q352 PolarHBondContact O-N 2.96Å
349C93.4Very high92.3Very high4 Ų444 Ų443%0.02722%0.22CC..Hα-helixtrans-67.5-38178.1-650000111.7F164 C165 V333 S345 L346 T347 T353F164-C349 HydrophobicContact CD1-CB 4.42Å; F164-C349 HydrophobicContact CE1-CB 3.47Å; F164-C349 VanDerWaalsContact CE1-CB 3.47Å; F164-C349 HydrophobicContact CZ-CB 3.58Å; C165-C349 WeakPolarHBondContact O-CB 3.3Å; V333-C349 HydrophobicContact CG1-CB 4.26Å; S345-C349 PolarHBondContact O-N 3.42Å; S345-C349 PolarHBondContact O-SG 3.16Å; L346-C349 PolarHBondContact O-N 2.7Å; T347-C349 VanDerWaalsContact C-N 3.33Å; T347-C349 PolarHBondContact O-N 2.82Å; C349-T353 WeakPolarHBondContact O-CB 3.35Å; C349-T353 PolarHBondContact O-N 3.17Å; C349-T353 PolarHBondContact O-OG1 3.41Å
350V91.6Very high92.7Very high9 Ų943.4 Ų43.46%0.05522%0.217CC..Hα-helixtrans-65.1-46.3174.8169.90000110.7T118 F164 L346 T347 Q352 T353 L354T118-V350 HydrophobicContact CG2-CG1 4.05Å; F164-V350 HydrophobicContact CE2-CG2 4.1Å; F164-V350 HydrophobicContact CZ-CG2 4.32Å; L346-V350 HydrophobicContact CD1-CG2 3.84Å; L346-V350 HydrophobicContact CG-CG2 4.43Å; L346-V350 VanDerWaalsContact O-CG2 3.31Å; L346-V350 WeakPolarHBondContact O-CG2 3.16Å; L346-V350 PolarHBondContact O-N 3.09Å; T347-V350 PolarHBondContact O-N 3.45Å; V350-Q352 PolarHBondContact O-N 2.99Å; V350-T353 WeakPolarHBondContact O-CB 3.32Å; V350-T353 PolarHBondContact O-N 3.31Å; V350-T353 VanDerWaalsContact O-N 3.15Å; V350-L354 HydrophobicContact CG1-CD1 4.31Å; V350-L354 WeakPolarHBondContact O-CG 3.49Å; V350-L354 PolarHBondContact O-N 2.77Å
351E92.5Very high92.9Very high104 Ų10447.2 Ų47.249%0.48624%0.236SC..Hα-helixtrans-56.9-50.7176.8-73.1169176.800111.8T347 K348 T353 L354 E355T347-E351 WeakPolarHBondContact O-CG 3.31Å; T347-E351 PolarHBondContact O-N 3Å; K348-E351 PolarHBondContact O-N 3.2Å; E351-T353 VanDerWaalsContact C-N 3.26Å; E351-T353 PolarHBondContact O-N 2.84Å; E351-L354 WeakPolarHBondContact O-CB 3.39Å; E351-L354 PolarHBondContact O-N 3.12Å; E351-E355 PolarHBondContact O-N 3.23Å
352Q92.5Very high93Very high84 Ų8450.5 Ų50.539%0.39326%0.264SS..Hα-helixtrans-60-36.6176.7-72.4177.8-15.900112.6C165 K348 V350 L354 E355 V356C165-Q352 HydrophobicContact CB-CB 3.66Å; K348-Q352 WeakPolarHBondContact O-CG 3.21Å; K348-Q352 PolarHBondContact O-N 2.96Å; V350-Q352 PolarHBondContact O-N 2.99Å; Q352-L354 VanDerWaalsContact C-N 3.32Å; Q352-L354 PolarHBondContact O-N 2.96Å; Q352-E355 WeakPolarHBondContact O-CB 3.18Å; Q352-E355 PolarHBondContact O-N 3.47Å; Q352-V356 PolarHBondContact O-N 3.48Å; Q352-V356 VanDerWaalsContact O-N 3.11Å
353T92.4Very high93Very high7 Ų754.5 Ų54.54%0.04328%0.28CS..Hα-helixtrans-66.7-35.2176.9-57.20000111.7D114 C165 C349 V350 E351 K357D114-T353 HydrophobicContact CB-CG2 4.26Å; C165-T353 PolarHBondContact N-OG1 3.23Å; C349-T353 WeakPolarHBondContact O-CB 3.35Å; C349-T353 PolarHBondContact O-N 3.17Å; C349-T353 PolarHBondContact O-OG1 3.41Å; V350-T353 WeakPolarHBondContact O-CB 3.32Å; V350-T353 PolarHBondContact O-N 3.31Å; V350-T353 VanDerWaalsContact O-N 3.15Å; E351-T353 VanDerWaalsContact C-N 3.26Å; E351-T353 PolarHBondContact O-N 2.84Å; T353-K357 PolarHBondContact O-N 2.92Å
354L91.4Very high93Very high91 Ų9155 Ų5548%0.47629%0.287SS..Hα-helixtrans-70.4-37.3173.1-66171.7000111.7V350 E351 Q352 V356 K357 A358V350-L354 HydrophobicContact CG1-CD1 4.31Å; V350-L354 WeakPolarHBondContact O-CG 3.49Å; V350-L354 PolarHBondContact O-N 2.77Å; E351-L354 WeakPolarHBondContact O-CB 3.39Å; E351-L354 PolarHBondContact O-N 3.12Å; Q352-L354 VanDerWaalsContact C-N 3.32Å; Q352-L354 PolarHBondContact O-N 2.96Å; L354-V356 VanDerWaalsContact C-N 3.3Å; L354-V356 PolarHBondContact O-N 3.04Å; L354-K357 HydrophobicContact CD2-CD 4.43Å; L354-K357 WeakPolarHBondContact O-CB 3.22Å; L354-K357 PolarHBondContact O-N 3.13Å; L354-K357 VanDerWaalsContact O-N 3.14Å; L354-A358 PolarHBondContact O-N 3.1Å
355E94.3Very high93Very high88 Ų8853.1 Ų53.141%0.41128%0.28SS..Hα-helixtrans-59.3-39.4174-72.2-179.6-150.700112.2E351 Q352 K357 A358 A359 R367 L371E351-E355 PolarHBondContact O-N 3.23Å; Q352-E355 WeakPolarHBondContact O-CB 3.18Å; Q352-E355 PolarHBondContact O-N 3.47Å; E355-K357 VanDerWaalsContact C-N 3.32Å; E355-K357 PolarHBondContact O-N 3.37Å; E355-A358 PolarHBondContact O-N 3.16Å; E355-A359 WeakPolarHBondContact O-CB 3.5Å; E355-A359 PolarHBondContact O-N 3.32Å; E355-R367 IonicContact OE2-NH2 2.84Å; E355-R367 PolarHBondContact OE2-NH2 3.27Å; E355-L371 HydrophobicContact CB-CD1 3.89Å
356V92.6Very high92.9Very high1 Ų159.6 Ų59.61%0.00631%0.306CS..Hα-helixtrans-60.3-44.6175.1174.90000111Q352 L354 A358 A359 L360 L371Q352-V356 PolarHBondContact O-N 3.48Å; Q352-V356 VanDerWaalsContact O-N 3.11Å; L354-V356 VanDerWaalsContact C-N 3.3Å; L354-V356 PolarHBondContact O-N 3.04Å; V356-A358 VanDerWaalsContact C-N 3.33Å; V356-A358 PolarHBondContact O-N 3.45Å; V356-A359 PolarHBondContact O-N 3.48Å; V356-L360 HydrophobicContact CG1-CD1 4.13Å; V356-L360 HydrophobicContact CG1-CG 4.48Å; V356-L360 WeakPolarHBondContact O-CG 3.45Å; V356-L360 PolarHBondContact O-N 3.38Å; V356-L371 HydrophobicContact CG2-CB 3.47Å; V356-L371 VanDerWaalsContact CG2-CB 3.47Å; V356-L371 HydrophobicContact CG2-CD1 4.01Å; V356-L371 HydrophobicContact CG2-CG 4.35Å
357K91.5Very high92.9Very high74 Ų7464.3 Ų64.332%0.32232%0.324SS..Hα-helixtrans-61.1-45.6178.7-66.8175-175.2173.50110.5D114 T353 L354 E355 A359 L360 D361D114-K357 IonicContact OD2-NZ 3.38Å; D114-K357 PolarHBondContact OD2-NZ 3.45Å; T353-K357 PolarHBondContact O-N 2.92Å; L354-K357 HydrophobicContact CD2-CD 4.43Å; L354-K357 WeakPolarHBondContact O-CB 3.22Å; L354-K357 PolarHBondContact O-N 3.13Å; L354-K357 VanDerWaalsContact O-N 3.14Å; E355-K357 VanDerWaalsContact C-N 3.32Å; E355-K357 PolarHBondContact O-N 3.37Å; K357-A359 PolarHBondContact O-N 3.23Å; K357-L360 PolarHBondContact O-N 3.37Å; K357-D361 PolarHBondContact O-N 2.75Å
358A95Very high93Very high59 Ų5963.1 Ų63.149%0.48832%0.317SS..Hα-helixtrans-61.8-42.3176.800000112.6L354 E355 V356 D361 A362L354-A358 PolarHBondContact O-N 3.1Å; E355-A358 PolarHBondContact O-N 3.16Å; V356-A358 VanDerWaalsContact C-N 3.33Å; V356-A358 PolarHBondContact O-N 3.45Å; A358-D361 PolarHBondContact O-N 3.46Å; A358-A362 VanDerWaalsContact O-CB 3.27Å; A358-A362 WeakPolarHBondContact O-CB 3.43Å; A358-A362 PolarHBondContact O-N 3.38Å
359A94.7Very high92.9Very high11 Ų1158.9 Ų58.99%0.09130%0.299CS..Hα-helixtrans-63-42.7177.500000112.1E355 V356 K357 A362 K363 D364 R367 A368 L371E355-A359 WeakPolarHBondContact O-CB 3.5Å; E355-A359 PolarHBondContact O-N 3.32Å; V356-A359 PolarHBondContact O-N 3.48Å; K357-A359 PolarHBondContact O-N 3.23Å; A359-A362 CarbonylContact O-C 3.41Å; A359-A362 PolarHBondContact O-N 2.94Å; A359-K363 PolarHBondContact O-N 3.48Å; A359-K363 VanDerWaalsContact O-N 3.13Å; A359-D364 PolarHBondContact O-N 2.89Å; A359-R367 HydrophobicContact CB-CB 4.34Å; A359-R367 HydrophobicContact CB-CG 4.18Å; A359-A368 HydrophobicContact CB-CB 4.3Å; A359-L371 HydrophobicContact CB-CD1 4.37Å
360L91.6Very high92.9Very high16 Ų1662.9 Ų62.98%0.08432%0.318CS..Hα-helixtrans-63.8-44175.5-70.2173000111.9V356 K357 A362 K363 W365 A368V356-L360 HydrophobicContact CG1-CD1 4.13Å; V356-L360 HydrophobicContact CG1-CG 4.48Å; V356-L360 WeakPolarHBondContact O-CG 3.45Å; V356-L360 PolarHBondContact O-N 3.38Å; K357-L360 PolarHBondContact O-N 3.37Å; L360-A362 VanDerWaalsContact C-N 3.3Å; L360-A362 PolarHBondContact O-N 3.4Å; L360-K363 PolarHBondContact O-N 3.49Å; L360-K363 VanDerWaalsContact O-N 3.14Å; L360-W365 HydrophobicContact CD2-CE3 4.05Å; L360-W365 HydrophobicContact CD2-CZ3 4.04Å; L360-W365 WeakPolarHBondContact O-CZ3 3.22Å; L360-A368 HydrophobicContact CD2-CB 3.69Å; L360-A368 HydrophobicContact CG-CB 4.07Å
361D92.4Very high92.8Very high105 Ų10563.8 Ų63.856%0.56132%0.322SS*.Hα-helixtrans-65.8-34.6178.1-69.1-28.5000111.7R206 K357 A358 K363R206-D361 IonicContact CZ-OD1 3.98Å; R206-D361 IonicContact NH1-OD1 3.59Å; R206-D361 PolarHBondContact NH1-OD1 3.28Å; R206-D361 IonicContact NH1-OD2 2.76Å; K357-D361 PolarHBondContact O-N 2.75Å; A358-D361 PolarHBondContact O-N 3.46Å; D361-K363 PolarHBondContact O-N 3.47Å
362A94.6Very high92.7Very high76 Ų7660.9 Ų60.963%0.62831%0.307SS*.THydrogen-bonded Turntrans-78.5-1.9175.200000114.2A358 A359 L360 D364A358-A362 VanDerWaalsContact O-CB 3.27Å; A358-A362 WeakPolarHBondContact O-CB 3.43Å; A358-A362 PolarHBondContact O-N 3.38Å; A359-A362 CarbonylContact O-C 3.41Å; A359-A362 PolarHBondContact O-N 2.94Å; L360-A362 VanDerWaalsContact C-N 3.3Å; L360-A362 PolarHBondContact O-N 3.4Å; A362-D364 PolarHBondContact O-N 3.29Å
363K93.5Very high92.5Very high107 Ų10758.1 Ų58.147%0.46530%0.3SS..THydrogen-bonded Turntrans61.926.3-175.7-50.6-176.1-170.6178.50114.4T265 A359 L360 D361 W365T265-K363 WeakPolarHBondContact O-CE 3.4Å; T265-K363 PolarHBondContact O-NZ 3.26Å; A359-K363 PolarHBondContact O-N 3.48Å; A359-K363 VanDerWaalsContact O-N 3.13Å; L360-K363 PolarHBondContact O-N 3.49Å; L360-K363 VanDerWaalsContact O-N 3.14Å; D361-K363 PolarHBondContact O-N 3.47Å; K363-W365 VanDerWaalsContact CA-CZ2 3.5Å; K363-W365 HydrophobicContact CB-CH2 3.78Å; K363-W365 HydrophobicContact CB-CZ2 3.34Å; K363-W365 HydrophobicContact CD-CZ2 4.21Å; K363-W365 HydrophobicContact CG-CH2 3.75Å; K363-W365 HydrophobicContact CG-CZ2 3.6Å; K363-W365 PolarHBondContact O-N 2.88Å; K363-W365 PolarHBondContact O-NE1 2.98Å
364D94.4Very high92.2Very high78 Ų7865.2 Ų65.242%0.41733%0.331SS..  trans-90.177.2172-169.8-11.4000110.5A359 A362 K366 R367 A368A359-D364 PolarHBondContact O-N 2.89Å; A362-D364 PolarHBondContact O-N 3.29Å; D364-K366 VanDerWaalsContact C-N 3.31Å; D364-K366 PolarHBondContact O-N 3.3Å; D364-R367 HydrophobicContact CB-CB 4.15Å; D364-R367 PolarHBondContact O-N 3.35Å; D364-R367 WeakPolarHBondContact OD1-CB 3.42Å; D364-R367 PolarHBondContact OD1-N 3.36Å; D364-R367 VanDerWaalsContact OD2-CB 3.27Å; D364-R367 WeakPolarHBondContact OD2-CB 3.45Å; D364-A368 PolarHBondContact O-N 2.67Å
365W91.9Very high92Very high50 Ų5062.2 Ų62.219%0.18932%0.316CS..Hα-helixtrans-64-35.9-175.4-41.5124.9000112.8P229 L360 K363 A368 I369P229-W365 HydrophobicContact CG-CD2 3.51Å; P229-W365 VanDerWaalsContact CG-CE2 3.4Å; P229-W365 HydrophobicContact CG-CE3 4.05Å; P229-W365 HydrophobicContact CG-CG 3.77Å; P229-W365 HydrophobicContact CG-CH2 4.35Å; P229-W365 HydrophobicContact CG-CZ2 3.85Å; P229-W365 HydrophobicContact CG-CZ3 4.45Å; L360-W365 HydrophobicContact CD2-CE3 4.05Å; L360-W365 HydrophobicContact CD2-CZ3 4.04Å; L360-W365 WeakPolarHBondContact O-CZ3 3.22Å; K363-W365 VanDerWaalsContact CA-CZ2 3.5Å; K363-W365 HydrophobicContact CB-CH2 3.78Å; K363-W365 HydrophobicContact CB-CZ2 3.34Å; K363-W365 HydrophobicContact CD-CZ2 4.21Å; K363-W365 HydrophobicContact CG-CH2 3.75Å; K363-W365 HydrophobicContact CG-CZ2 3.6Å; K363-W365 PolarHBondContact O-N 2.88Å; K363-W365 PolarHBondContact O-NE1 2.98Å; W365-A368 PolarHBondContact O-N 2.82Å; W365-I369 WeakPolarHBondContact O-CG1 3.38Å; W365-I369 PolarHBondContact O-N 3.23Å
366K92.3Very high91.8Very high151 Ų15158.4 Ų58.466%0.65730%0.298SS*.Hα-helixtrans-65.2-47.3179.7-174-178.5175.4-1720109.8D364 A368 I369 E370D364-K366 VanDerWaalsContact C-N 3.31Å; D364-K366 PolarHBondContact O-N 3.3Å; K366-A368 VanDerWaalsContact C-N 3.31Å; K366-A368 PolarHBondContact O-N 3.09Å; K366-I369 PolarHBondContact O-N 2.84Å; K366-E370 VanDerWaalsContact CE-OE1 3.24Å; K366-E370 WeakPolarHBondContact CE-OE1 3.44Å; K366-E370 WeakPolarHBondContact O-CG 3.48Å; K366-E370 PolarHBondContact O-N 3.26Å
367R93.7Very high91.7Very high100 Ų10062 Ų6238%0.37732%0.315SS..Hα-helixtrans-62.9-38.8175.8-177.358179.7165.32.2112E355 A359 D364 I369 E370 L371E355-R367 IonicContact OE2-NH2 2.84Å; E355-R367 PolarHBondContact OE2-NH2 3.27Å; A359-R367 HydrophobicContact CB-CB 4.34Å; A359-R367 HydrophobicContact CB-CG 4.18Å; D364-R367 HydrophobicContact CB-CB 4.15Å; D364-R367 PolarHBondContact O-N 3.35Å; D364-R367 WeakPolarHBondContact OD1-CB 3.42Å; D364-R367 PolarHBondContact OD1-N 3.36Å; D364-R367 VanDerWaalsContact OD2-CB 3.27Å; D364-R367 WeakPolarHBondContact OD2-CB 3.45Å; R367-I369 PolarHBondContact O-N 3.37Å; R367-E370 IonicContact NH1-OE2 2.96Å; R367-E370 PolarHBondContact O-N 3.43Å; R367-L371 HydrophobicContact CG-CD1 3.9Å; R367-L371 HydrophobicContact CG-CG 4.28Å; R367-L371 WeakPolarHBondContact O-CB 3.12Å; R367-L371 VanDerWaalsContact O-CG 3.28Å; R367-L371 WeakPolarHBondContact O-CG 3.47Å; R367-L371 PolarHBondContact O-N 2.79Å
368A92.9Very high91.6Very high0 Ų065.1 Ų65.10%032%0.324CS..Hα-helixtrans-59.3-46.817600000112.1A359 L360 D364 W365 K366 L371 R372A359-A368 HydrophobicContact CB-CB 4.3Å; L360-A368 HydrophobicContact CD2-CB 3.69Å; L360-A368 HydrophobicContact CG-CB 4.07Å; D364-A368 PolarHBondContact O-N 2.67Å; W365-A368 PolarHBondContact O-N 2.82Å; K366-A368 VanDerWaalsContact C-N 3.31Å; K366-A368 PolarHBondContact O-N 3.09Å; A368-L371 PolarHBondContact O-N 3.35Å; A368-R372 VanDerWaalsContact O-CG 3.3Å; A368-R372 WeakPolarHBondContact O-CG 3.32Å; A368-R372 PolarHBondContact O-N 3.15Å
369I92.3Very high91.5Very high21 Ų2162.3 Ų62.311%0.10830%0.302CS..Hα-helixtrans-62.7-43.9176.2-68.9171.6000111.3E227 W365 K366 R367 L371 R372 G373 F376 Q377E227-I369 HydrophobicContact CB-CG1 3.96Å; E227-I369 WeakPolarHBondContact O-CD1 3.36Å; W365-I369 WeakPolarHBondContact O-CG1 3.38Å; W365-I369 PolarHBondContact O-N 3.23Å; K366-I369 PolarHBondContact O-N 2.84Å; R367-I369 PolarHBondContact O-N 3.37Å; I369-L371 VanDerWaalsContact C-N 3.34Å; I369-L371 PolarHBondContact O-N 3.47Å; I369-R372 PolarHBondContact O-N 3.45Å; I369-G373 PolarHBondContact O-N 3.45Å; I369-F376 HydrophobicContact CG2-CD1 4.46Å; I369-Q377 HydrophobicContact CG2-CB 4.04Å; I369-Q377 HydrophobicContact CG2-CG 4.19Å
370E92.1Very high91.3Very high89 Ų8963.1 Ų63.142%0.41630%0.303SS..Hα-helixtrans-60.7-43.5178.3-73.9173.7-173.600111.9K366 R367 G373K366-E370 VanDerWaalsContact CE-OE1 3.24Å; K366-E370 WeakPolarHBondContact CE-OE1 3.44Å; K366-E370 WeakPolarHBondContact O-CG 3.48Å; K366-E370 PolarHBondContact O-N 3.26Å; R367-E370 IonicContact NH1-OE2 2.96Å; R367-E370 PolarHBondContact O-N 3.43Å; E370-G373 WeakPolarHBondContact O-CA 3.16Å; E370-G373 PolarHBondContact O-N 2.82Å; E370-G373 VanDerWaalsContact O-N 3.1Å
371L91Very high91.3Very high28 Ų2867 Ų6715%0.14732%0.321CS..Hα-helixtrans-67.3-34.2178.6-75.6171.7000113E355 V356 A359 R367 A368 I369 G373E355-L371 HydrophobicContact CB-CD1 3.89Å; V356-L371 HydrophobicContact CG2-CB 3.47Å; V356-L371 VanDerWaalsContact CG2-CB 3.47Å; V356-L371 HydrophobicContact CG2-CD1 4.01Å; V356-L371 HydrophobicContact CG2-CG 4.35Å; A359-L371 HydrophobicContact CB-CD1 4.37Å; R367-L371 HydrophobicContact CG-CD1 3.9Å; R367-L371 HydrophobicContact CG-CG 4.28Å; R367-L371 WeakPolarHBondContact O-CB 3.12Å; R367-L371 VanDerWaalsContact O-CG 3.28Å; R367-L371 WeakPolarHBondContact O-CG 3.47Å; R367-L371 PolarHBondContact O-N 2.79Å; A368-L371 PolarHBondContact O-N 3.35Å; I369-L371 VanDerWaalsContact C-N 3.34Å; I369-L371 PolarHBondContact O-N 3.47Å; L371-G373 PolarHBondContact O-N 3.01Å
372R89.5Confident91.1Very high43 Ų4362.5 Ų62.516%0.16230%0.298CS..Hα-helixtrans-62.6-22.4171.6-70-71.2-169.4-148.5-1.5112.5D163 R206 C207 E227 A368 I369 F376D163-R372 VanDerWaalsContact CA-NH1 3.31Å; D163-R372 PolarHBondContact O-NH1 3.12Å; R206-R372 PolarHBondContact O-NH2 3.01Å; C207-R372 VanDerWaalsContact SG-CZ 3.56Å; E227-R372 HydrophobicContact CG-CG 4.33Å; E227-R372 IonicContact OE1-CZ 3.99Å; E227-R372 IonicContact OE1-NE 3.17Å; E227-R372 PolarHBondContact OE1-NE 2.79Å; E227-R372 IonicContact OE1-NH2 3.18Å; E227-R372 PolarHBondContact OE1-NH2 3.22Å; A368-R372 VanDerWaalsContact O-CG 3.3Å; A368-R372 WeakPolarHBondContact O-CG 3.32Å; A368-R372 PolarHBondContact O-N 3.15Å; I369-R372 PolarHBondContact O-N 3.45Å; R372-F376 HydrophobicContact CB-CB 3.78Å; R372-F376 HydrophobicContact CB-CD1 4.22Å; R372-F376 HydrophobicContact CB-CD2 4.01Å; R372-F376 HydrophobicContact CB-CG 3.75Å; R372-F376 HydrophobicContact CG-CD2 4.28Å; R372-F376 HydrophobicContact CG-CG 4.35Å
373G88Confident91Very high25 Ų2559.2 Ų59.226%0.25827%0.269SS..  trans100.9169171.500000114.9I369 E370 L371 T375 F376 Q377I369-G373 PolarHBondContact O-N 3.45Å; E370-G373 WeakPolarHBondContact O-CA 3.16Å; E370-G373 PolarHBondContact O-N 2.82Å; E370-G373 VanDerWaalsContact O-N 3.1Å; L371-G373 PolarHBondContact O-N 3.01Å; G373-T375 VanDerWaalsContact C-N 3.28Å; G373-T375 PolarHBondContact O-N 2.93Å; G373-F376 WeakPolarHBondContact O-CB 3.48Å; G373-F376 PolarHBondContact O-N 2.88Å; G373-F376 VanDerWaalsContact O-N 3.13Å; G373-Q377 PolarHBondContact O-N 3.06Å
374K86.9Confident90.8Very high157 Ų15757.2 Ų57.268%0.68326%0.264SS*.Hα-helixtrans-60.1-34.4-171.7-65-179.3179.6177.50113.4Q377 R378K374-Q377 PolarHBondContact O-N 3.35Å; K374-R378 WeakPolarHBondContact O-CB 3.37Å; K374-R378 VanDerWaalsContact O-CG 3.28Å; K374-R378 WeakPolarHBondContact O-CG 3.47Å; K374-R378 PolarHBondContact O-N 3.37Å
375T86.6Confident90.4Very high27 Ų2754.6 Ų54.617%0.16625%0.25CC..Hα-helixtrans-64.2-44.7178.8-56.20000110.6D168 G373 R378 N379D168-T375 PolarHBondContact OD1-OG1 2.9Å; G373-T375 VanDerWaalsContact C-N 3.28Å; G373-T375 PolarHBondContact O-N 2.93Å; T375-R378 PolarHBondContact O-N 2.82Å; T375-N379 VanDerWaalsContact O-CG 3.28Å; T375-N379 PolarHBondContact O-N 3.44Å; T375-N379 VanDerWaalsContact O-N 3.09Å; T375-N379 PolarHBondContact O-ND2 2.96Å; T375-N379 VanDerWaalsContact O-ND2 3.09Å
376F90.1Very high90.1Very high8 Ų852.6 Ų52.64%0.03524%0.243CC..Hα-helixtrans-60.6-49.1176.6-166.8-78.5000111.1Y209 L212 E227 I369 R372 G373 R378 N379 F380Y209-F376 AromaticContact CD2-CD2 3.84Å; Y209-F376 HydrophobicContact CD2-CD2 3.84Å; Y209-F376 HydrophobicContact CD2-CE2 4.18Å; L212-F376 HydrophobicContact CD2-CD1 4.35Å; L212-F376 HydrophobicContact CD2-CE1 3.99Å; L212-F376 HydrophobicContact CD2-CE2 4.34Å; L212-F376 HydrophobicContact CD2-CZ 3.97Å; E227-F376 HydrophobicContact CB-CE1 4.03Å; E227-F376 HydrophobicContact CB-CZ 4.11Å; E227-F376 HydrophobicContact CG-CE1 4.2Å; E227-F376 HydrophobicContact CG-CZ 3.94Å; I369-F376 HydrophobicContact CG2-CD1 4.46Å; R372-F376 HydrophobicContact CB-CB 3.78Å; R372-F376 HydrophobicContact CB-CD1 4.22Å; R372-F376 HydrophobicContact CB-CD2 4.01Å; R372-F376 HydrophobicContact CB-CG 3.75Å; R372-F376 HydrophobicContact CG-CD2 4.28Å; R372-F376 HydrophobicContact CG-CG 4.35Å; G373-F376 WeakPolarHBondContact O-CB 3.48Å; G373-F376 PolarHBondContact O-N 2.88Å; G373-F376 VanDerWaalsContact O-N 3.13Å; F376-R378 VanDerWaalsContact C-N 3.35Å; F376-R378 PolarHBondContact O-N 2.94Å; F376-N379 PolarHBondContact O-N 2.92Å; F376-F380 WeakPolarHBondContact O-CB 3.35Å; F376-F380 PolarHBondContact O-N 2.57Å
377Q91Very high89.8Confident76 Ų7646.3 Ų46.336%0.35522%0.217SC..Hα-helixtrans-58.1-44.1178.8-174.5-176-6.300112.5I369 G373 K374 N379 F380 E381I369-Q377 HydrophobicContact CG2-CB 4.04Å; I369-Q377 HydrophobicContact CG2-CG 4.19Å; G373-Q377 PolarHBondContact O-N 3.06Å; K374-Q377 PolarHBondContact O-N 3.35Å; Q377-N379 PolarHBondContact O-N 3.09Å; Q377-F380 WeakPolarHBondContact O-CB 3.36Å; Q377-F380 PolarHBondContact O-N 2.87Å; Q377-E381 WeakPolarHBondContact CG-OE1 3.44Å; Q377-E381 PolarHBondContact NE2-OE1 3.38Å; Q377-E381 WeakPolarHBondContact O-CG 3.29Å; Q377-E381 PolarHBondContact O-N 3.46Å
378R90.1Very high89.3Confident140 Ų14045.1 Ų45.153%0.52822%0.215SC..Hα-helixtrans-63.7-39.9177.5-74.7169.9174.4178.1-5112.6K374 T375 F376 F380 E381 A382K374-R378 WeakPolarHBondContact O-CB 3.37Å; K374-R378 VanDerWaalsContact O-CG 3.28Å; K374-R378 WeakPolarHBondContact O-CG 3.47Å; K374-R378 PolarHBondContact O-N 3.37Å; T375-R378 PolarHBondContact O-N 2.82Å; F376-R378 VanDerWaalsContact C-N 3.35Å; F376-R378 PolarHBondContact O-N 2.94Å; R378-F380 VanDerWaalsContact C-N 3.29Å; R378-E381 PolarHBondContact O-N 3.19Å; R378-A382 VanDerWaalsContact O-CB 3.29Å; R378-A382 WeakPolarHBondContact O-CB 3.44Å; R378-A382 PolarHBondContact O-N 2.84Å
379N92.2Very high88.5Confident1 Ų146 Ų461%0.00522%0.219CC..Hα-helixtrans-64.7-40.4176.1-68.1-32.9000110.7L212 I213 I216 T375 F376 Q377 A382 Y383L212-N379 HydrophobicContact CD2-CB 3.98Å; L212-N379 HydrophobicContact CG-CB 4.35Å; I213-N379 HydrophobicContact CD1-CB 3.98Å; I213-N379 VanDerWaalsContact CD1-ND2 3.3Å; I213-N379 WeakPolarHBondContact CD1-ND2 3.46Å; I216-N379 HydrophobicContact CD1-CB 3.86Å; I216-N379 VanDerWaalsContact CD1-O 3.31Å; I216-N379 WeakPolarHBondContact CD1-O 3.12Å; T375-N379 VanDerWaalsContact O-CG 3.28Å; T375-N379 PolarHBondContact O-N 3.44Å; T375-N379 VanDerWaalsContact O-N 3.09Å; T375-N379 PolarHBondContact O-ND2 2.96Å; T375-N379 VanDerWaalsContact O-ND2 3.09Å; F376-N379 PolarHBondContact O-N 2.92Å; Q377-N379 PolarHBondContact O-N 3.09Å; N379-A382 PolarHBondContact O-N 2.92Å; N379-Y383 PolarHBondContact O-N 2.81Å
380F91.2Very high87.9Confident27 Ų2748.3 Ų48.312%0.11823%0.23CC..Hα-helixtrans-60-49.6175.6176.6-93.7000112.1L212 W228 F376 Q377 R378 A382 Y383 N384L212-F380 HydrophobicContact CD2-CB 4.15Å; W228-F380 HydrophobicContact CB-CD2 4.22Å; W228-F380 HydrophobicContact CB-CE2 3.46Å; W228-F380 VanDerWaalsContact CB-CE2 3.46Å; W228-F380 HydrophobicContact CB-CZ 4.05Å; W228-F380 AromaticContact CD1-CE2 3.98Å; W228-F380 AromaticContact CD1-CZ 3.64Å; W228-F380 AromaticContact CD2-CE2 3.18Å; W228-F380 HydrophobicContact CD2-CE2 3.18Å; W228-F380 AromaticContact CD2-CZ 3.22Å; W228-F380 HydrophobicContact CD2-CZ 3.22Å; W228-F380 AromaticContact CE2-CE2 3.84Å; W228-F380 AromaticContact CE2-CZ 3.33Å; W228-F380 HydrophobicContact CE3-CD2 4.49Å; W228-F380 AromaticContact CE3-CE2 3.28Å; W228-F380 HydrophobicContact CE3-CE2 3.28Å; W228-F380 AromaticContact CE3-CZ 3.65Å; W228-F380 HydrophobicContact CE3-CZ 3.65Å; W228-F380 HydrophobicContact CG-CD2 4.41Å; W228-F380 AromaticContact CG-CE2 3.27Å; W228-F380 HydrophobicContact CG-CE2 3.27Å; W228-F380 AromaticContact CG-CZ 3.4Å; W228-F380 HydrophobicContact CG-CZ 3.4Å; W228-F380 HydrophobicContact CH2-CE2 4.41Å; W228-F380 HydrophobicContact CH2-CZ 4.06Å; W228-F380 HydrophobicContact CZ2-CE2 4.41Å; W228-F380 AromaticContact CZ2-CZ 3.77Å; W228-F380 HydrophobicContact CZ2-CZ 3.77Å; W228-F380 AromaticContact CZ3-CE2 3.9Å; W228-F380 HydrophobicContact CZ3-CE2 3.9Å; W228-F380 HydrophobicContact CZ3-CZ 4.03Å; W228-F380 AromaticContact NE1-CZ 3.63Å; F376-F380 WeakPolarHBondContact O-CB 3.35Å; F376-F380 PolarHBondContact O-N 2.57Å; Q377-F380 WeakPolarHBondContact O-CB 3.36Å; Q377-F380 PolarHBondContact O-N 2.87Å; R378-F380 VanDerWaalsContact C-N 3.29Å; F380-A382 VanDerWaalsContact C-N 3.34Å; F380-A382 PolarHBondContact O-N 3.43Å; F380-Y383 PolarHBondContact O-N 2.76Å; F380-N384 WeakPolarHBondContact O-CB 3.27Å; F380-N384 PolarHBondContact O-N 3.13Å
381E90.1Very high87.1Confident99 Ų9946.4 Ų46.446%0.46323%0.225SC..Hα-helixtrans-60.1-43.4175.8-71.2166.3-174.100111.8Q377 R378 N384 L385Q377-E381 WeakPolarHBondContact CG-OE1 3.44Å; Q377-E381 PolarHBondContact NE2-OE1 3.38Å; Q377-E381 WeakPolarHBondContact O-CG 3.29Å; Q377-E381 PolarHBondContact O-N 3.46Å; R378-E381 PolarHBondContact O-N 3.19Å; E381-N384 PolarHBondContact O-N 2.81Å; E381-L385 WeakPolarHBondContact O-CB 3.3Å; E381-L385 PolarHBondContact O-N 3.45Å
382A89.7Confident86.2Confident9 Ų946.6 Ų46.67%0.07423%0.228CC..Hα-helixtrans-60.3-46.617700000112R378 N379 F380 L385 L386 I684R378-A382 VanDerWaalsContact O-CB 3.29Å; R378-A382 WeakPolarHBondContact O-CB 3.44Å; R378-A382 PolarHBondContact O-N 2.84Å; N379-A382 PolarHBondContact O-N 2.92Å; F380-A382 VanDerWaalsContact C-N 3.34Å; F380-A382 PolarHBondContact O-N 3.43Å; A382-L385 PolarHBondContact O-N 3.46Å; A382-L386 VanDerWaalsContact O-CB 3.3Å; A382-L386 WeakPolarHBondContact O-CB 3.3Å; A382-L386 VanDerWaalsContact O-CG 3.28Å; A382-L386 WeakPolarHBondContact O-CG 3.49Å; A382-L386 PolarHBondContact O-N 3.37Å; A382-I684 HydrophobicContact CB-CD1 3.48Å; A382-I684 VanDerWaalsContact CB-CD1 3.48Å
383Y92Very high85.1Confident8 Ų851.4 Ų51.43%0.03126%0.261CS..Hα-helixtrans-61.6-48.2176.3169.9-98.9000111.8L212 S215 I216 W222 V223 W228 N379 F380 L385 L386 S387L212-Y383 HydrophobicContact CD1-CD1 4.42Å; L212-Y383 HydrophobicContact CD1-CG 4.1Å; S215-Y383 WeakPolarHBondContact OG-CD2 3.44Å; S215-Y383 WeakPolarHBondContact OG-CE2 3.32Å; I216-Y383 HydrophobicContact CG1-CD2 4.41Å; W222-Y383 VanDerWaalsContact C-OH 3.28Å; W222-Y383 WeakPolarHBondContact CA-OH 3.25Å; V223-Y383 HydrophobicContact CB-CE1 4.3Å; V223-Y383 HydrophobicContact CB-CE2 4.33Å; V223-Y383 HydrophobicContact CG1-CD1 3.85Å; V223-Y383 HydrophobicContact CG1-CE1 3.29Å; V223-Y383 HydrophobicContact CG1-CE2 4.07Å; V223-Y383 HydrophobicContact CG1-CG 4.45Å; V223-Y383 VanDerWaalsContact CG1-CZ 3.42Å; V223-Y383 PolarHBondContact N-OH 3.2Å; W228-Y383 HydrophobicContact CZ3-CE1 4.43Å; N379-Y383 PolarHBondContact O-N 2.81Å; F380-Y383 PolarHBondContact O-N 2.76Å; Y383-L385 PolarHBondContact O-N 3.35Å; Y383-L386 PolarHBondContact O-N 2.78Å; Y383-S387 WeakPolarHBondContact O-CB 3.21Å; Y383-S387 PolarHBondContact O-N 2.84Å; Y383-S387 PolarHBondContact O-OG 2.81Å
384N88.2Confident84.1Confident65 Ų6554.3 Ų54.335%0.34827%0.271SS..Hα-helixtrans-60.6-34.9-178.5-175.640.9000112.1F380 E381 K388F380-N384 WeakPolarHBondContact O-CB 3.27Å; F380-N384 PolarHBondContact O-N 3.13Å; E381-N384 PolarHBondContact O-N 2.81Å; N384-K388 WeakPolarHBondContact O-CG 3.13Å
385L85.8Confident82.7Confident23 Ų2355.9 Ų55.912%0.1228%0.278CS..Hα-helixtrans-75.1-53176-170.4155.3000111.7E381 A382 Y383 S387 K388 M428 Y431E381-L385 WeakPolarHBondContact O-CB 3.3Å; E381-L385 PolarHBondContact O-N 3.45Å; A382-L385 PolarHBondContact O-N 3.46Å; Y383-L385 PolarHBondContact O-N 3.35Å; L385-S387 VanDerWaalsContact C-N 3.3Å; L385-S387 PolarHBondContact O-N 3.3Å; L385-K388 PolarHBondContact O-N 3.48Å; L385-M428 HydrophobicContact CD1-CE 4.01Å; L385-M428 HydrophobicContact CD1-SD 3.86Å; L385-M428 HydrophobicContact CD2-CE 4.48Å; L385-M428 HydrophobicContact CD2-SD 3.33Å; L385-M428 WeakPolarHBondContact CD2-SD 3.45Å; L385-M428 HydrophobicContact CG-SD 4.25Å; L385-Y431 HydrophobicContact CD1-CD1 4.2Å; L385-Y431 HydrophobicContact CD1-CD2 3.78Å; L385-Y431 HydrophobicContact CD1-CE1 4.02Å; L385-Y431 HydrophobicContact CD1-CE2 3.52Å; L385-Y431 HydrophobicContact CD1-CG 4.15Å; L385-Y431 HydrophobicContact CD2-CD2 3.86Å; L385-Y431 HydrophobicContact CD2-CE2 4.36Å; L385-Y431 HydrophobicContact CD2-CG 4.24Å; L385-Y431 HydrophobicContact CG-CD2 3.64Å; L385-Y431 HydrophobicContact CG-CE2 3.62Å; L385-Y431 HydrophobicContact CG-CG 4.33Å
386L86.1Confident81.9Confident8 Ų863.1 Ų63.14%0.04231%0.31CS..Hα-helixtrans-72.5-23.1-171.4-68.2174.1000113.3A382 Y383 K388 R427 T680 I684A382-L386 VanDerWaalsContact O-CB 3.3Å; A382-L386 WeakPolarHBondContact O-CB 3.3Å; A382-L386 VanDerWaalsContact O-CG 3.28Å; A382-L386 WeakPolarHBondContact O-CG 3.49Å; A382-L386 PolarHBondContact O-N 3.37Å; Y383-L386 PolarHBondContact O-N 2.78Å; L386-K388 VanDerWaalsContact C-N 3.27Å; L386-K388 PolarHBondContact O-N 2.93Å; L386-R427 HydrophobicContact CD2-CB 4.11Å; L386-R427 PolarHBondContact O-NH1 3.27Å; L386-T680 HydrophobicContact CD1-CG2 3.41Å; L386-T680 VanDerWaalsContact CD1-CG2 3.41Å; L386-I684 HydrophobicContact CD1-CD1 4.08Å
387S85.5Confident81.6Confident18 Ų1863.9 Ų63.913%0.12631%0.314CS..THydrogen-bonded Turntrans-81.40.3178.4710000113.8K241 Y383 L385K241-S387 WeakPolarHBondContact CE-O 3.27Å; K241-S387 PolarHBondContact NZ-O 3.48Å; K241-S387 PolarHBondContact NZ-OG 2.97Å; Y383-S387 WeakPolarHBondContact O-CB 3.21Å; Y383-S387 PolarHBondContact O-N 2.84Å; Y383-S387 PolarHBondContact O-OG 2.81Å; L385-S387 VanDerWaalsContact C-N 3.3Å; L385-S387 PolarHBondContact O-N 3.3Å
388K83.5Confident81.4Confident76 Ų7663.1 Ų63.133%0.3331%0.312SS..  trans-70.9143.4176.2-66.6-177.3179.3-176.90111.4N384 L385 L386 P392 W456N384-K388 WeakPolarHBondContact O-CG 3.13Å; L385-K388 PolarHBondContact O-N 3.48Å; L386-K388 VanDerWaalsContact C-N 3.27Å; L386-K388 PolarHBondContact O-N 2.93Å; K388-P392 HydrophobicContact CD-CB 4.48Å; K388-P392 HydrophobicContact CD-CG 4.23Å; K388-W456 HydrophobicContact CB-CZ2 4.37Å; K388-W456 VanDerWaalsContact O-CZ2 3.3Å; K388-W456 WeakPolarHBondContact O-CZ2 3.42Å; K388-W456 PolarHBondContact O-NE1 3.46Å
389M77.4Confident81.1Confident19 Ų1956.5 Ų56.59%0.09429%0.287CS..SBendtrans-74.3-30.2177.4-70.7-53.1-5300112.9K241 E244 S245 Y248 W456K241-M389 HydrophobicContact CG-CG 4.34Å; E244-M389 HydrophobicContact CB-CG 4.39Å; S245-M389 VanDerWaalsContact CA-CE 3.46Å; Y248-M389 HydrophobicContact CD2-CE 4.35Å; M389-W456 PolarHBondContact O-NE1 3.29Å
390H78.9Confident80.8Confident69 Ų6958.3 Ų58.332%0.31931%0.307SS..SBendtrans-127.2150.4-179.5-62.1-33.7000110.8Y248 P392Y248-H390 AromaticContact CD2-CE1 3.67Å; Y248-H390 AromaticContact CE1-CE1 3.74Å; Y248-H390 AromaticContact CE2-CE1 2.99Å; Y248-H390 WeakPolarHBondContact CE2-CE1 3.49Å; Y248-H390 AromaticContact CE2-NE2 3.16Å; Y248-H390 WeakPolarHBondContact CE2-NE2 3.47Å; Y248-H390 AromaticContact CZ-CE1 3Å; Y248-H390 AromaticContact CZ-NE2 3.4Å; Y248-H390 PolarHBondContact OH-CE1 3.03Å; Y248-H390 PolarHBondContact OH-NE2 3.49Å; Y248-H390 VanDerWaalsContact OH-NE2 3.14Å; H390-P392 WeakPolarHBondContact O-CD 3.34Å; H390-P392 VanDerWaalsContact O-N 3.17Å
391P76.4Confident80.5Confident49 Ų4959.8 Ų59.832%0.31833%0.33SS..  trans-55.9124.3163.824.9-31.2000107.2V393 L430 W456P391-V393 PolarHBondContact O-N 2.9Å; P391-L430 HydrophobicContact CB-CB 4.46Å; P391-W456 HydrophobicContact CB-CE3 3.81Å; P391-W456 HydrophobicContact CB-CZ3 3.8Å; P391-W456 HydrophobicContact CG-CE3 4.17Å
392P71.4Confident80.4Confident31 Ų3158 Ų5820%0.20132%0.323CS..  trans-63.3141.2179.620.4-24.7000109.7K388 H390 D394 Y431K388-P392 HydrophobicContact CD-CB 4.48Å; K388-P392 HydrophobicContact CD-CG 4.23Å; H390-P392 WeakPolarHBondContact O-CD 3.34Å; H390-P392 VanDerWaalsContact O-N 3.17Å; P392-D394 PolarHBondContact O-N 2.81Å; P392-Y431 HydrophobicContact CB-CE2 4.4Å; P392-Y431 HydrophobicContact CG-CD2 3.14Å; P392-Y431 HydrophobicContact CG-CE2 3.05Å; P392-Y431 HydrophobicContact CG-CG 4.14Å
393V66.7Low80.3Confident144 Ų14466 Ų6687%0.87336%0.356SS*.  trans-80.829.7-177.8-157.90000111.2P391 K395P391-V393 PolarHBondContact O-N 2.9Å; V393-K395 PolarHBondContact O-N 2.9Å
394D65.7Low80.5Confident86 Ų8665.6 Ų65.646%0.4635%0.354SS..  trans-69.2121.9-173.1-155.4-23000109.9P392 Q396 N397P392-D394 PolarHBondContact O-N 2.81Å; D394-Q396 PolarHBondContact O-N 3.41Å; D394-Q396 PolarHBondContact OD1-N 2.97Å; D394-Q396 VanDerWaalsContact OD1-N 3.1Å; D394-N397 PolarHBondContact O-ND2 3.3Å
395K57.7Low81Confident190 Ų19063.8 Ų63.883%0.82634%0.344SS*.SBendtrans-72.9-19.5178.5-68.1-173.8179.7-178.30111.4V393 N397V393-K395 PolarHBondContact O-N 2.9Å; K395-N397 VanDerWaalsContact C-N 3.35Å; K395-N397 PolarHBondContact O-N 3.23Å
396Q70.1Confident81.5Confident180 Ų18062.7 Ų62.784%0.84134%0.339SS*.SBendtrans-98.247.9177.1-66.3-173.6-1.200111.9D394D394-Q396 PolarHBondContact O-N 3.41Å; D394-Q396 PolarHBondContact OD1-N 2.97Å; D394-Q396 VanDerWaalsContact OD1-N 3.1Å
397N83.4Confident82.1Confident23 Ų2362.3 Ų62.312%0.12334%0.337CS..SBendtrans-83.7167.3172.662.829.5000111.6D394 K395 S399 G400D394-N397 PolarHBondContact O-ND2 3.3Å; K395-N397 VanDerWaalsContact C-N 3.35Å; K395-N397 PolarHBondContact O-N 3.23Å; N397-S399 PolarHBondContact O-N 3.03Å; N397-S399 PolarHBondContact OD1-N 3.44Å; N397-S399 PolarHBondContact OD1-OG 3.08Å; N397-G400 PolarHBondContact O-N 3.45Å; N397-G400 PolarHBondContact OD1-N 3.04Å
398L87.2Confident82.8Confident60 Ų6061.4 Ų61.431%0.31433%0.331SS..THydrogen-bonded Turntrans-61.2-29.4-178-69.3178000113.5G400 H432 Q688 V691 R695L398-G400 PolarHBondContact O-N 2.92Å; L398-H432 VanDerWaalsContact CD1-CE1 3.49Å; L398-H432 WeakPolarHBondContact CD1-CE1 3.18Å; L398-H432 PolarHBondContact N-ND1 3.47Å; L398-Q688 HydrophobicContact CD1-CB 3.74Å; L398-Q688 HydrophobicContact CD1-CG 3.79Å; L398-V691 HydrophobicContact CB-CG1 3.85Å; L398-R695 WeakPolarHBondContact O-CD 3.27Å; L398-R695 PolarHBondContact O-NH1 3.29Å
399S84.6Confident83.5Confident1 Ų157.8 Ų57.81%0.00732%0.315CS..THydrogen-bonded Turntrans-70.6-13.7177.566.60000113.2N397 G401 L402 H432N397-S399 PolarHBondContact O-N 3.03Å; N397-S399 PolarHBondContact OD1-N 3.44Å; N397-S399 PolarHBondContact OD1-OG 3.08Å; S399-G401 PolarHBondContact O-N 3.07Å; S399-L402 WeakPolarHBondContact CB-O 3.36Å; S399-L402 WeakPolarHBondContact O-CB 3.15Å; S399-L402 PolarHBondContact O-N 2.98Å; S399-L402 PolarHBondContact OG-O 3.21Å; S399-H432 VanDerWaalsContact CB-O 3.24Å; S399-H432 WeakPolarHBondContact CB-O 3.32Å; S399-H432 PolarHBondContact OG-O 2.94Å
400G85.5Confident84.5Confident40 Ų4056.9 Ų56.941%0.41231%0.311SS..THydrogen-bonded Turntrans6422.9-179.700000113.1N397 L398N397-G400 PolarHBondContact O-N 3.45Å; N397-G400 PolarHBondContact OD1-N 3.04Å; L398-G400 PolarHBondContact O-N 2.92Å
401G83.7Confident85.4Confident58 Ų5853.6 Ų53.660%0.59830%0.295SS*.THydrogen-bonded Turntrans90-6.1-176.900000115.3S399S399-G401 PolarHBondContact O-N 3.07Å
402L88Confident86.4Confident61 Ų6151.3 Ų51.332%0.31928%0.281SS..  trans-71.1145.3172-65.2172.1000110.8S399 F404 R695 A698S399-L402 WeakPolarHBondContact CB-O 3.36Å; S399-L402 WeakPolarHBondContact O-CB 3.15Å; S399-L402 PolarHBondContact O-N 2.98Å; S399-L402 PolarHBondContact OG-O 3.21Å; L402-F404 HydrophobicContact CB-CE1 4.05Å; L402-F404 HydrophobicContact CB-CE2 3.91Å; L402-F404 HydrophobicContact CB-CZ 3.57Å; L402-F404 HydrophobicContact CD1-CE1 4.28Å; L402-F404 HydrophobicContact CD1-CZ 3.67Å; L402-F404 HydrophobicContact CG-CZ 4.28Å; L402-R695 HydrophobicContact CD1-CG 4.45Å; L402-A698 HydrophobicContact CD1-CB 3.91Å
403K89.5Confident87.5Confident176 Ų17651.9 Ų51.977%0.76529%0.285SS*.  trans-105.494.1-178.4-67.9-174.3-179.3179.20110.5
404F95.3Very high88.9Confident0 Ų047.2 Ų47.20%026%0.258CS..  trans-87.4146.6175.5-55.3-58.6000112L402 L406 C434 K435 N494 A694 R695 A698 V704L402-F404 HydrophobicContact CB-CE1 4.05Å; L402-F404 HydrophobicContact CB-CE2 3.91Å; L402-F404 HydrophobicContact CB-CZ 3.57Å; L402-F404 HydrophobicContact CD1-CE1 4.28Å; L402-F404 HydrophobicContact CD1-CZ 3.67Å; L402-F404 HydrophobicContact CG-CZ 4.28Å; F404-L406 HydrophobicContact CB-CD2 4.14Å; F404-C434 HydrophobicContact CB-CB 4.44Å; F404-C434 CarbonylContact O-C 3.56Å; F404-C434 VanDerWaalsContact O-CA 3.31Å; F404-C434 WeakPolarHBondContact O-CA 3.37Å; F404-C434 VanDerWaalsContact O-CB 3.29Å; F404-C434 WeakPolarHBondContact O-CB 3.3Å; F404-K435 PolarHBondContact O-N 3.49Å; F404-N494 WeakPolarHBondContact CA-OD1 3.38Å; F404-N494 HydrophobicContact CB-CB 4.1Å; F404-N494 HydrophobicContact CD1-CB 4.18Å; F404-A694 HydrophobicContact CD1-CB 4.21Å; F404-A694 HydrophobicContact CD2-CB 4.11Å; F404-A694 HydrophobicContact CE1-CB 4.24Å; F404-A694 HydrophobicContact CE2-CB 4.14Å; F404-A694 HydrophobicContact CG-CB 4.15Å; F404-A694 HydrophobicContact CZ-CB 4.21Å; F404-R695 HydrophobicContact CE2-CB 4.09Å; F404-R695 HydrophobicContact CZ-CB 4.1Å; F404-A698 HydrophobicContact CE1-CB 4.07Å; F404-A698 HydrophobicContact CZ-CB 4.19Å; F404-V704 HydrophobicContact CD1-CG2 3.79Å; F404-V704 HydrophobicContact CE1-CG2 3.66Å
405N97.7Very high90.3Very high27 Ų2743.1 Ų43.114%0.14424%0.236CC..EExtended strand (participates in β ladder)trans-97106.5166.6-68.8-5.8000109.1K435 Y437 Y491 K492 I493 N494N405-K435 CarbonylContact C-O 3.6Å; N405-K435 WeakPolarHBondContact CA-O 3.26Å; N405-Y437 HydrophobicContact CB-CD2 4.29Å; N405-Y437 HydrophobicContact CB-CE2 4.02Å; N405-Y491 PolarHBondContact ND2-O 3.06Å; N405-K492 WeakPolarHBondContact CB-O 3.38Å; N405-I493 HydrophobicContact CB-CD1 4.36Å; N405-I493 CarbonylContact O-C 3.5Å; N405-N494 PolarHBondContact N-OD1 3.41Å; N405-N494 PolarHBondContact O-N 3.21Å
406L98.2Very high92.2Very high0 Ų034.1 Ų34.10%020%0.197CC..EExtended strand (participates in β ladder)trans-90.5147.4174.4-48179.7000109.4F404 F425 C434 K435 V436 Y437 A495 V691F404-L406 HydrophobicContact CB-CD2 4.14Å; L406-F425 HydrophobicContact CB-CE1 4.08Å; L406-F425 HydrophobicContact CB-CZ 4.04Å; L406-F425 HydrophobicContact CD1-CZ 4.17Å; L406-C434 HydrophobicContact CD1-CB 3.84Å; L406-C434 HydrophobicContact CG-CB 3.9Å; L406-K435 PolarHBondContact N-O 2.96Å; L406-V436 HydrophobicContact CB-CG2 4.44Å; L406-V436 HydrophobicContact CD1-CG2 4.49Å; L406-V436 CarbonylContact O-C 3.59Å; L406-V436 WeakPolarHBondContact O-CA 3.34Å; L406-Y437 PolarHBondContact O-N 2.74Å; L406-A495 WeakPolarHBondContact CA-O 3.28Å; L406-A495 HydrophobicContact CD2-CB 3.78Å; L406-V691 HydrophobicContact CD1-CG2 3.94Å
407A98.6Very high93.4Very high0 Ų025.5 Ų25.50%016%0.157CC..EExtended strand (participates in β ladder)trans-121.9148.3170.800000111.7Y437 I439 I493 A495 L496 L497A407-Y437 CarbonylContact C-O 3.6Å; A407-Y437 VanDerWaalsContact CA-O 3.27Å; A407-Y437 WeakPolarHBondContact CA-O 3.26Å; A407-I439 HydrophobicContact CB-CD1 3.89Å; A407-I439 HydrophobicContact CB-CG1 4.48Å; A407-I493 HydrophobicContact CB-CD1 3.93Å; A407-I493 HydrophobicContact CB-CG1 4.14Å; A407-I493 HydrophobicContact CB-CG2 3.67Å; A407-A495 PolarHBondContact N-O 3.05Å; A407-L496 HydrophobicContact CB-CD1 3.77Å; A407-L497 PolarHBondContact O-N 2.96Å
408V98.7Very high94.1Very high0 Ų024.4 Ų24.40%015%0.151CC..EExtended strand (participates in β ladder)trans-133.3139.4172.6610000110.9V422 F425 V426 V436 Y437 I439 L470 L497 V499V408-V422 HydrophobicContact CG1-CG1 4.13Å; V408-V422 HydrophobicContact CG2-CG2 4.02Å; V408-F425 HydrophobicContact CB-CD1 3.69Å; V408-F425 HydrophobicContact CB-CE1 3.9Å; V408-F425 HydrophobicContact CG1-CD1 4.07Å; V408-F425 HydrophobicContact CG1-CE1 4.5Å; V408-F425 HydrophobicContact CG2-CD1 4.19Å; V408-V426 HydrophobicContact CG1-CG2 4.44Å; V408-V436 HydrophobicContact CG1-CG1 4.42Å; V408-Y437 PolarHBondContact N-O 3.18Å; V408-I439 PolarHBondContact O-N 3.46Å; V408-L470 HydrophobicContact CG1-CD1 4.48Å; V408-L497 WeakPolarHBondContact CA-O 3.49Å; V408-L497 HydrophobicContact CB-CB 4.27Å; V408-L497 HydrophobicContact CG2-CB 4.11Å; V408-L497 HydrophobicContact CG2-CD2 3.84Å; V408-L497 HydrophobicContact CG2-CG 3.98Å; V408-V499 HydrophobicContact CG2-CG2 4.25Å
409M98.4Very high94.6Very high0 Ų021.6 Ų21.60%014%0.136CC..EExtended strand (participates in β ladder)trans-144152.3174.381.7174.796.100111.8V411 I439 F443 L446 L496 L497 L498 V499M409-V411 HydrophobicContact CG-CG2 3.69Å; M409-V411 HydrophobicContact SD-CG2 3.85Å; M409-I439 HydrophobicContact CB-CB 3.73Å; M409-I439 HydrophobicContact CB-CD1 4.17Å; M409-I439 HydrophobicContact CB-CG1 4.47Å; M409-I439 HydrophobicContact CB-CG2 4.12Å; M409-I439 HydrophobicContact CE-CD1 3.63Å; M409-I439 HydrophobicContact SD-CD1 4.49Å; M409-I439 HydrophobicContact SD-CG2 4.45Å; M409-F443 HydrophobicContact CE-CD1 4.43Å; M409-F443 HydrophobicContact CE-CE1 3.85Å; M409-F443 HydrophobicContact CE-CZ 3.9Å; M409-F443 HydrophobicContact SD-CD1 4.45Å; M409-F443 HydrophobicContact SD-CD2 4.2Å; M409-F443 HydrophobicContact SD-CE1 4.2Å; M409-F443 HydrophobicContact SD-CE2 3.95Å; M409-F443 HydrophobicContact SD-CG 4.45Å; M409-F443 HydrophobicContact SD-CZ 3.95Å; M409-L446 HydrophobicContact CE-CD2 4.02Å; M409-L496 HydrophobicContact CE-CD1 3.7Å; M409-L496 HydrophobicContact CE-CD2 3.94Å; M409-L496 HydrophobicContact CE-CG 4.34Å; M409-L497 PolarHBondContact N-O 3.41Å; M409-L498 HydrophobicContact CE-CD2 3.87Å; M409-L498 HydrophobicContact CG-CD2 3.74Å; M409-L498 HydrophobicContact SD-CD2 3.87Å; M409-V499 PolarHBondContact O-N 2.76Å
410N98.6Very high95.1Very high0 Ų021.5 Ų21.50%014%0.136CC..EExtended strand (participates in β ladder)trans-97.3137.2171.6-64.1-17.7000109.5M418 V422 S442 S468 V499N410-M418 HydrophobicContact CB-SD 4.09Å; N410-V422 WeakPolarHBondContact OD1-CG2 3.34Å; N410-S442 WeakPolarHBondContact O-CB 3.32Å; N410-S442 PolarHBondContact O-OG 3.28Å; N410-S468 PolarHBondContact ND2-OG 3.22Å; N410-V499 CarbonylContact C-O 3.52Å; N410-V499 WeakPolarHBondContact CA-O 3.4Å; N410-V499 WeakPolarHBondContact OD1-CB 3.17Å
411V98.3Very high95.7Very high0 Ų019.6 Ų19.60%012%0.116CC..EExtended strand (participates in β ladder)trans-137.2135.7-177.5-170.80000110.9M409 F443 L498 V499 G500 G501 E503 A504M409-V411 HydrophobicContact CG-CG2 3.69Å; M409-V411 HydrophobicContact SD-CG2 3.85Å; V411-F443 HydrophobicContact CG1-CD2 4.45Å; V411-F443 HydrophobicContact CG1-CE2 4.28Å; V411-F443 HydrophobicContact CG2-CD2 4.4Å; V411-F443 HydrophobicContact CG2-CE2 3.96Å; V411-L498 HydrophobicContact CG2-CD2 3.76Å; V411-V499 PolarHBondContact N-O 3.38Å; V411-G500 WeakPolarHBondContact O-CA 3.33Å; V411-G501 PolarHBondContact O-N 3.22Å; V411-E503 HydrophobicContact CG1-CB 3.93Å; V411-A504 HydrophobicContact CB-CB 3.92Å
412G97Very high96.4Very high1 Ų116.9 Ų16.91%0.019%0.088CC..SBendtrans100.1-156.7-178.100000112.8S472 Q473G412-S472 CarbonylContact O-C 3.58Å; G412-S472 WeakPolarHBondContact O-CB 3.38Å; G412-S472 PolarHBondContact O-OG 3.24Å; G412-Q473 PolarHBondContact N-O 3.42Å
413S95.8Very high96.8Very high43 Ų4314.3 Ų14.330%0.3017%0.074SC..SBendtrans-72.6142.6177.4-72.90000111.8M418 K474S413-M418 WeakPolarHBondContact O-CE 3.17Å; S413-K474 WeakPolarHBondContact OG-CE 3.4Å
414P95.7Very high97.1Very high45 Ų455.9 Ų5.929%0.2924%0.037SC..  trans-60.6142.2176.125.9-33.5000110.9
415S95.2Very high97.2Very high0 Ų05.9 Ų5.90%04%0.037CC..  trans-146.3148-176.8-168.70000110.1M418 I543 G544S415-M418 WeakPolarHBondContact O-CG 3.4Å; S415-M418 PolarHBondContact O-N 2.87Å; S415-I543 PolarHBondContact OG-O 3.31Å; S415-G544 WeakPolarHBondContact OG-CA 3.33Å
416C95.9Very high97.1Very high1 Ų14.6 Ų4.61%0.0073%0.03CC..THydrogen-bonded Turntrans-59.1139.7171.5-80.30000110.7I543 G544 T547 Q667 A671C416-I543 WeakPolarHBondContact O-CG2 3.18Å; C416-G544 VanDerWaalsContact O-CA 3.27Å; C416-G544 WeakPolarHBondContact O-CA 3.11Å; C416-G544 PolarHBondContact O-N 3.25Å; C416-T547 HydrophobicContact CB-CG2 3.95Å; C416-Q667 PolarHBondContact SG-O 3.01Å; C416-A671 HydrophobicContact CB-CB 3.73Å
417G96Very high96.9Very high0 Ų05.3 Ų5.30%03%0.033CC..THydrogen-bonded Turntrans92.4-11.4179.900000115.8N419 A420 A421 A679G417-N419 VanDerWaalsContact C-N 3.34Å; G417-N419 PolarHBondContact O-N 3.17Å; G417-A420 PolarHBondContact O-N 3.42Å; G417-A421 PolarHBondContact O-N 3.33Å; G417-A679 WeakPolarHBondContact O-CB 3.2Å
418M97.6Very high96.6Very high0 Ų05.3 Ų5.30%03%0.033CC..Hα-helixtrans-55.3-48.5172.2-73.6-174.6167.500112N410 S413 S415 A420 A421 V422 V499 C530N410-M418 HydrophobicContact CB-SD 4.09Å; S413-M418 WeakPolarHBondContact O-CE 3.17Å; S415-M418 WeakPolarHBondContact O-CG 3.4Å; S415-M418 PolarHBondContact O-N 2.87Å; M418-A420 VanDerWaalsContact C-N 3.33Å; M418-A420 PolarHBondContact O-N 2.64Å; M418-A421 PolarHBondContact O-N 3.39Å; M418-V422 WeakPolarHBondContact O-CG2 3.14Å; M418-V422 PolarHBondContact O-N 3.42Å; M418-V499 HydrophobicContact CG-CG1 4.31Å; M418-C530 HydrophobicContact CE-CB 4.46Å; M418-C530 HydrophobicContact CG-CB 4.3Å; M418-C530 WeakPolarHBondContact CG-SG 3.08Å
419N97.7Very high96.4Very high0 Ų05.3 Ų5.30%03%0.033CC..Hα-helixtrans-64.1-37.7-179.6-60.1-40.6000112.2G417 V422 R423 W462 Y465 G466 G467 S468 F469G417-N419 VanDerWaalsContact C-N 3.34Å; G417-N419 PolarHBondContact O-N 3.17Å; N419-V422 PolarHBondContact O-N 3.08Å; N419-R423 WeakPolarHBondContact O-CB 3.22Å; N419-R423 PolarHBondContact O-N 3.46Å; N419-W462 HydrophobicContact CB-CB 4.21Å; N419-W462 HydrophobicContact CB-CE3 4.31Å; N419-W462 WeakPolarHBondContact CB-O 3.49Å; N419-Y465 PolarHBondContact ND2-O 3.23Å; N419-G466 PolarHBondContact ND2-O 2.93Å; N419-G467 PolarHBondContact ND2-O 2.97Å; N419-S468 WeakPolarHBondContact OD1-CA 3.31Å; N419-F469 PolarHBondContact OD1-N 3.26Å
420A96.7Very high96.2Very high0 Ų06.8 Ų6.80%04%0.041CC..Hα-helixtrans-63.9-43.2175.500000112G417 M418 C424 T463 A679G417-A420 PolarHBondContact O-N 3.42Å; M418-A420 VanDerWaalsContact C-N 3.33Å; M418-A420 PolarHBondContact O-N 2.64Å; A420-C424 WeakPolarHBondContact O-CB 3.48Å; A420-C424 PolarHBondContact O-N 3.17Å; A420-T463 HydrophobicContact CB-CG2 3.91Å; A420-A679 HydrophobicContact CB-CB 3.79Å
421A97.6Very high95.8Very high0 Ų09 Ų90%05%0.049CC..Hα-helixtrans-62.6-48.3176.200000111.4G417 M418 R423 C424 F425 V499 A679 A683G417-A421 PolarHBondContact O-N 3.33Å; M418-A421 PolarHBondContact O-N 3.39Å; A421-R423 PolarHBondContact O-N 2.77Å; A421-C424 PolarHBondContact O-N 2.95Å; A421-F425 WeakPolarHBondContact O-CB 3.35Å; A421-F425 PolarHBondContact O-N 3.11Å; A421-V499 HydrophobicContact CB-CG1 4.08Å; A421-V499 HydrophobicContact CB-CG2 4.26Å; A421-A679 HydrophobicContact CB-CB 4.13Å; A421-A683 HydrophobicContact CB-CB 4.39Å; A421-A683 VanDerWaalsContact O-CB 3.27Å; A421-A683 WeakPolarHBondContact O-CB 3.43Å
422V97.9Very high95.5Very high0 Ų09.3 Ų9.30%05%0.051CC..Hα-helixtrans-59-49.3178.11720000111.2V408 N410 M418 N419 C424 F425 V426 W462 L470V408-V422 HydrophobicContact CG1-CG1 4.13Å; V408-V422 HydrophobicContact CG2-CG2 4.02Å; N410-V422 WeakPolarHBondContact OD1-CG2 3.34Å; M418-V422 WeakPolarHBondContact O-CG2 3.14Å; M418-V422 PolarHBondContact O-N 3.42Å; N419-V422 PolarHBondContact O-N 3.08Å; V422-C424 VanDerWaalsContact C-N 3.31Å; V422-C424 PolarHBondContact O-N 2.89Å; V422-F425 PolarHBondContact O-N 2.97Å; V422-V426 HydrophobicContact CG1-CG2 4.35Å; V422-V426 VanDerWaalsContact O-CG2 3.32Å; V422-V426 WeakPolarHBondContact O-CG2 3.35Å; V422-V426 PolarHBondContact O-N 2.98Å; V422-W462 HydrophobicContact CB-CE3 4.43Å; V422-W462 HydrophobicContact CB-CZ3 4.34Å; V422-W462 HydrophobicContact CG1-CE3 4.15Å; V422-W462 HydrophobicContact CG1-CZ3 3.72Å; V422-L470 HydrophobicContact CG1-CD1 3.92Å; V422-L470 HydrophobicContact CG1-CG 4.42Å; V422-L470 HydrophobicContact CG2-CD1 3.94Å
423R96.2Very high95.1Very high7 Ų711 Ų113%0.0267%0.069CC..Hα-helixtrans-54-50.8178170.8-170.7176.9-90.98111.6E219 N419 A421 V426 R427 V459 W462 T463E219-R423 VanDerWaalsContact CD-NH2 3.26Å; E219-R423 VanDerWaalsContact CG-NH2 3.35Å; E219-R423 VanDerWaalsContact OE1-CD 3.28Å; E219-R423 WeakPolarHBondContact OE1-CD 3.24Å; E219-R423 IonicContact OE1-CZ 3.92Å; E219-R423 IonicContact OE1-NE 3.84Å; E219-R423 PolarHBondContact OE1-NE 3.33Å; E219-R423 VanDerWaalsContact OE1-NE 3.07Å; E219-R423 IonicContact OE2-CZ 3.67Å; E219-R423 IonicContact OE2-NE 3.91Å; E219-R423 PolarHBondContact OE2-NE 2.88Å; E219-R423 IonicContact OE2-NH2 3.48Å; E219-R423 PolarHBondContact OE2-NH2 3.29Å; N419-R423 WeakPolarHBondContact O-CB 3.22Å; N419-R423 PolarHBondContact O-N 3.46Å; A421-R423 PolarHBondContact O-N 2.77Å; R423-V426 PolarHBondContact O-N 3.42Å; R423-R427 VanDerWaalsContact NH2-NH1 3.1Å; R423-R427 PolarHBondContact O-N 3.09Å; R423-V459 HydrophobicContact CB-CB 3.98Å; R423-V459 HydrophobicContact CB-CG2 4.28Å; R423-V459 WeakPolarHBondContact CD-O 3.17Å; R423-V459 HydrophobicContact CG-CB 3.91Å; R423-V459 HydrophobicContact CG-CG2 3.8Å; R423-V459 WeakPolarHBondContact CG-O 3.28Å; R423-W462 HydrophobicContact CB-CB 4.04Å; R423-T463 WeakPolarHBondContact CD-OG1 3.4Å; R423-T463 PolarHBondContact NE-OG1 3.06Å
424C95.6Very high95Very high0 Ų09.2 Ų9.20%06%0.056CC..Hα-helixtrans-65.9-42.7-175.7-173.70000111.1A420 A421 V422 V426 R427 M428 T680 A683 I684A420-C424 WeakPolarHBondContact O-CB 3.48Å; A420-C424 PolarHBondContact O-N 3.17Å; A421-C424 PolarHBondContact O-N 2.95Å; V422-C424 VanDerWaalsContact C-N 3.31Å; V422-C424 PolarHBondContact O-N 2.89Å; C424-V426 PolarHBondContact O-N 2.96Å; C424-R427 PolarHBondContact O-N 2.79Å; C424-M428 WeakPolarHBondContact O-CB 3.26Å; C424-M428 VanDerWaalsContact O-CG 3.23Å; C424-M428 WeakPolarHBondContact O-CG 3.34Å; C424-M428 PolarHBondContact O-N 2.89Å; C424-T680 HydrophobicContact CB-CG2 4.43Å; C424-T680 PolarHBondContact SG-O 2.99Å; C424-T680 VanDerWaalsContact SG-O 3.34Å; C424-A683 HydrophobicContact CB-CB 3.66Å; C424-I684 WeakPolarHBondContact SG-CG1 3.29Å
425F97.2Very high95Very high0 Ų011.3 Ų11.30%06%0.06CC..Hα-helixtrans-59.1-44.9174.8-176.5-102.3000112.5L406 V408 A421 V422 M428 G429 V436 L497 A683 A687 L690L406-F425 HydrophobicContact CB-CE1 4.08Å; L406-F425 HydrophobicContact CB-CZ 4.04Å; L406-F425 HydrophobicContact CD1-CZ 4.17Å; V408-F425 HydrophobicContact CB-CD1 3.69Å; V408-F425 HydrophobicContact CB-CE1 3.9Å; V408-F425 HydrophobicContact CG1-CD1 4.07Å; V408-F425 HydrophobicContact CG1-CE1 4.5Å; V408-F425 HydrophobicContact CG2-CD1 4.19Å; A421-F425 WeakPolarHBondContact O-CB 3.35Å; A421-F425 PolarHBondContact O-N 3.11Å; V422-F425 PolarHBondContact O-N 2.97Å; F425-M428 PolarHBondContact O-N 2.97Å; F425-G429 PolarHBondContact O-N 3.23Å; F425-V436 HydrophobicContact CD1-CG1 4.14Å; F425-V436 HydrophobicContact CE1-CG1 4.08Å; F425-L497 HydrophobicContact CB-CD2 3.75Å; F425-L497 HydrophobicContact CD1-CB 4.43Å; F425-L497 HydrophobicContact CD1-CD2 3.93Å; F425-L497 HydrophobicContact CD2-CB 4.32Å; F425-L497 HydrophobicContact CD2-CD2 3.33Å; F425-L497 HydrophobicContact CD2-CG 4.41Å; F425-L497 HydrophobicContact CE1-CB 4.05Å; F425-L497 HydrophobicContact CE1-CD2 4.35Å; F425-L497 HydrophobicContact CE2-CB 3.94Å; F425-L497 HydrophobicContact CE2-CD2 3.82Å; F425-L497 HydrophobicContact CE2-CG 4.47Å; F425-L497 HydrophobicContact CG-CD2 3.38Å; F425-L497 HydrophobicContact CZ-CB 3.78Å; F425-L497 HydrophobicContact CZ-CD2 4.29Å; F425-A683 HydrophobicContact CB-CB 4.43Å; F425-A687 HydrophobicContact CD2-CB 3.68Å; F425-A687 HydrophobicContact CE2-CB 3.98Å; F425-L690 HydrophobicContact CE2-CD1 3.92Å; F425-L690 HydrophobicContact CZ-CD1 4.08Å
426V96.3Very high95.2Very high0 Ų011.3 Ų11.30%06%0.06CC..Hα-helixtrans-59-50.4176.6168.40000111V408 V422 R423 C424 M428 G429 L430 V436 M454 V459V408-V426 HydrophobicContact CG1-CG2 4.44Å; V422-V426 HydrophobicContact CG1-CG2 4.35Å; V422-V426 VanDerWaalsContact O-CG2 3.32Å; V422-V426 WeakPolarHBondContact O-CG2 3.35Å; V422-V426 PolarHBondContact O-N 2.98Å; R423-V426 PolarHBondContact O-N 3.42Å; C424-V426 PolarHBondContact O-N 2.96Å; V426-M428 VanDerWaalsContact C-N 3.31Å; V426-M428 PolarHBondContact O-N 2.91Å; V426-G429 PolarHBondContact O-N 2.66Å; V426-L430 HydrophobicContact CG1-CD1 3.9Å; V426-L430 VanDerWaalsContact O-CG 3.26Å; V426-L430 WeakPolarHBondContact O-CG 3.29Å; V426-L430 PolarHBondContact O-N 3.4Å; V426-L430 VanDerWaalsContact O-N 3.08Å; V426-V436 HydrophobicContact CB-CG1 4.46Å; V426-V436 HydrophobicContact CG2-CB 4.48Å; V426-V436 HydrophobicContact CG2-CG1 3.82Å; V426-M454 HydrophobicContact CG1-CB 3.7Å; V426-M454 HydrophobicContact CG2-CB 4.04Å; V426-M454 HydrophobicContact CG2-CG 4.07Å; V426-V459 HydrophobicContact CB-CG1 4.11Å; V426-V459 HydrophobicContact CB-CG2 4.27Å; V426-V459 HydrophobicContact CG1-CG1 4.06Å; V426-V459 HydrophobicContact CG1-CG2 4.03Å; V426-V459 HydrophobicContact CG2-CG1 4.1Å
427R93.7Very high95.3Very high14 Ų1412.4 Ų12.45%0.0537%0.065CC..Hα-helixtrans-61.9-39.7178.8-73.8-167.1175-172.83.8112L386 R423 C424 Y431 W456 V459L386-R427 HydrophobicContact CD2-CB 4.11Å; L386-R427 PolarHBondContact O-NH1 3.27Å; R423-R427 VanDerWaalsContact NH2-NH1 3.1Å; R423-R427 PolarHBondContact O-N 3.09Å; C424-R427 PolarHBondContact O-N 2.79Å; R427-Y431 VanDerWaalsContact O-CB 3.23Å; R427-Y431 WeakPolarHBondContact O-CB 3.34Å; R427-Y431 PolarHBondContact O-N 2.94Å; R427-W456 HydrophobicContact CB-CE3 4.35Å; R427-W456 HydrophobicContact CB-CH2 4.09Å; R427-W456 HydrophobicContact CB-CZ2 4.47Å; R427-W456 HydrophobicContact CB-CZ3 4.04Å; R427-W456 HydrophobicContact CG-CD2 4.21Å; R427-W456 HydrophobicContact CG-CE3 4.27Å; R427-W456 HydrophobicContact CG-CH2 4.4Å; R427-W456 HydrophobicContact CG-CZ2 4.32Å; R427-W456 HydrophobicContact CG-CZ3 4.38Å; R427-W456 WeakPolarHBondContact O-CZ3 3.46Å; R427-V459 HydrophobicContact CG-CG2 4.22Å
428M93.6Very high95.4Very high0 Ų012.4 Ų12.40%07%0.065CC..Hα-helixtrans-69.3-41.3179.3-71.2-61.4-51.600113L385 C424 F425 V426 Y431 H432 I684 A687 Q688L385-M428 HydrophobicContact CD1-CE 4.01Å; L385-M428 HydrophobicContact CD1-SD 3.86Å; L385-M428 HydrophobicContact CD2-CE 4.48Å; L385-M428 HydrophobicContact CD2-SD 3.33Å; L385-M428 WeakPolarHBondContact CD2-SD 3.45Å; L385-M428 HydrophobicContact CG-SD 4.25Å; C424-M428 WeakPolarHBondContact O-CB 3.26Å; C424-M428 VanDerWaalsContact O-CG 3.23Å; C424-M428 WeakPolarHBondContact O-CG 3.34Å; C424-M428 PolarHBondContact O-N 2.89Å; F425-M428 PolarHBondContact O-N 2.97Å; V426-M428 VanDerWaalsContact C-N 3.31Å; V426-M428 PolarHBondContact O-N 2.91Å; M428-Y431 WeakPolarHBondContact O-CB 3.37Å; M428-Y431 PolarHBondContact O-N 3.05Å; M428-H432 WeakPolarHBondContact CE-NE2 3.23Å; M428-H432 PolarHBondContact O-CD2 2.92Å; M428-H432 PolarHBondContact O-N 3.42Å; M428-I684 HydrophobicContact CE-CG2 4.07Å; M428-I684 HydrophobicContact CG-CG1 4.15Å; M428-I684 HydrophobicContact SD-CG1 4.18Å; M428-I684 HydrophobicContact SD-CG2 4.23Å; M428-A687 HydrophobicContact CB-CB 3.35Å; M428-A687 HydrophobicContact CG-CB 4.19Å; M428-Q688 HydrophobicContact CE-CG 3.83Å
429G94.2Very high95.5Very high0 Ų012.4 Ų12.40%07%0.065CC..Hα-helixtrans-59.3-48.117400000111.7F425 V426 Y431 H432 G433 C434F425-G429 PolarHBondContact O-N 3.23Å; V426-G429 PolarHBondContact O-N 2.66Å; G429-Y431 PolarHBondContact O-N 3.34Å; G429-H432 CarbonylContact O-C 3.58Å; G429-H432 PolarHBondContact O-N 3.27Å; G429-H432 VanDerWaalsContact O-N 3.16Å; G429-G433 PolarHBondContact O-N 3.46Å; G429-C434 VanDerWaalsContact O-CB 3.27Å; G429-C434 WeakPolarHBondContact O-CB 3.39Å; G429-C434 PolarHBondContact O-N 3.45Å
430L93.3Very high95.5Very high32 Ų3216.8 Ų16.817%0.1688%0.084CC..Hα-helixtrans-64.6-38.7177.3-65.5171.6000112.4P391 V426 H432 G433 V436 W456P391-L430 HydrophobicContact CB-CB 4.46Å; V426-L430 HydrophobicContact CG1-CD1 3.9Å; V426-L430 VanDerWaalsContact O-CG 3.26Å; V426-L430 WeakPolarHBondContact O-CG 3.29Å; V426-L430 PolarHBondContact O-N 3.4Å; V426-L430 VanDerWaalsContact O-N 3.08Å; L430-H432 PolarHBondContact O-N 3.07Å; L430-G433 PolarHBondContact O-N 3.34Å; L430-V436 HydrophobicContact CG-CG2 4.33Å; L430-W456 HydrophobicContact CB-CE3 3.95Å; L430-W456 HydrophobicContact CB-CZ3 4.3Å; L430-W456 HydrophobicContact CD1-CB 4.16Å; L430-W456 HydrophobicContact CD1-CE3 4.24Å
431Y90.7Very high95.5Very high46 Ų4619 Ų1918%0.1810%0.096CC..Hα-helixtrans-57.6-37.8174171.1-80.7000111.3L385 P392 R427 M428 G429 G433L385-Y431 HydrophobicContact CD1-CD1 4.2Å; L385-Y431 HydrophobicContact CD1-CD2 3.78Å; L385-Y431 HydrophobicContact CD1-CE1 4.02Å; L385-Y431 HydrophobicContact CD1-CE2 3.52Å; L385-Y431 HydrophobicContact CD1-CG 4.15Å; L385-Y431 HydrophobicContact CD2-CD2 3.86Å; L385-Y431 HydrophobicContact CD2-CE2 4.36Å; L385-Y431 HydrophobicContact CD2-CG 4.24Å; L385-Y431 HydrophobicContact CG-CD2 3.64Å; L385-Y431 HydrophobicContact CG-CE2 3.62Å; L385-Y431 HydrophobicContact CG-CG 4.33Å; P392-Y431 HydrophobicContact CB-CE2 4.4Å; P392-Y431 HydrophobicContact CG-CD2 3.14Å; P392-Y431 HydrophobicContact CG-CE2 3.05Å; P392-Y431 HydrophobicContact CG-CG 4.14Å; R427-Y431 VanDerWaalsContact O-CB 3.23Å; R427-Y431 WeakPolarHBondContact O-CB 3.34Å; R427-Y431 PolarHBondContact O-N 2.94Å; M428-Y431 WeakPolarHBondContact O-CB 3.37Å; M428-Y431 PolarHBondContact O-N 3.05Å; G429-Y431 PolarHBondContact O-N 3.34Å; Y431-G433 VanDerWaalsContact C-N 3.26Å; Y431-G433 PolarHBondContact O-N 2.87Å
432H91Very high95.5Very high6 Ų619 Ų193%0.02810%0.096CC..THydrogen-bonded Turntrans-87.218176.2-65.3-57.5000113.9L398 S399 M428 G429 L430 C434 V691L398-H432 VanDerWaalsContact CD1-CE1 3.49Å; L398-H432 WeakPolarHBondContact CD1-CE1 3.18Å; L398-H432 PolarHBondContact N-ND1 3.47Å; S399-H432 VanDerWaalsContact CB-O 3.24Å; S399-H432 WeakPolarHBondContact CB-O 3.32Å; S399-H432 PolarHBondContact OG-O 2.94Å; M428-H432 WeakPolarHBondContact CE-NE2 3.23Å; M428-H432 PolarHBondContact O-CD2 2.92Å; M428-H432 PolarHBondContact O-N 3.42Å; G429-H432 CarbonylContact O-C 3.58Å; G429-H432 PolarHBondContact O-N 3.27Å; G429-H432 VanDerWaalsContact O-N 3.16Å; L430-H432 PolarHBondContact O-N 3.07Å; H432-C434 PolarHBondContact O-N 2.91Å; H432-V691 HydrophobicContact CB-CG1 4.07Å; H432-V691 HydrophobicContact CB-CG2 4.23Å
433G89.5Confident95.5Very high38 Ų3819 Ų1939%0.39210%0.096SC..THydrogen-bonded Turntrans71.712.4175.500000114.9G429 L430 Y431G429-G433 PolarHBondContact O-N 3.46Å; L430-G433 PolarHBondContact O-N 3.34Å; Y431-G433 VanDerWaalsContact C-N 3.26Å; Y431-G433 PolarHBondContact O-N 2.87Å
434C93.5Very high95.5Very high5 Ų522.6 Ų22.63%0.03411%0.113CC..  trans-86.8156.4177.5-55.80000110.7F404 L406 G429 H432F404-C434 HydrophobicContact CB-CB 4.44Å; F404-C434 CarbonylContact O-C 3.56Å; F404-C434 VanDerWaalsContact O-CA 3.31Å; F404-C434 WeakPolarHBondContact O-CA 3.37Å; F404-C434 VanDerWaalsContact O-CB 3.29Å; F404-C434 WeakPolarHBondContact O-CB 3.3Å; L406-C434 HydrophobicContact CD1-CB 3.84Å; L406-C434 HydrophobicContact CG-CB 3.9Å; G429-C434 VanDerWaalsContact O-CB 3.27Å; G429-C434 WeakPolarHBondContact O-CB 3.39Å; G429-C434 PolarHBondContact O-N 3.45Å; H432-C434 PolarHBondContact O-N 2.91Å
435K96.2Very high95.6Very high88 Ų8822.6 Ų22.638%0.38311%0.113SC..EExtended strand (participates in β ladder)trans-85.7143.7162.6-70-173.9164.8-132.30109.1F404 N405 L406 Y437 E453F404-K435 PolarHBondContact O-N 3.49Å; N405-K435 CarbonylContact C-O 3.6Å; N405-K435 WeakPolarHBondContact CA-O 3.26Å; L406-K435 PolarHBondContact N-O 2.96Å; K435-Y437 HydrophobicContact CB-CE2 4.25Å; K435-E453 WeakPolarHBondContact CE-OE1 3.46Å; K435-E453 IonicContact NZ-OE1 2.66Å; K435-E453 PolarHBondContact NZ-OE1 3.19Å; K435-E453 IonicContact NZ-OE2 3.93Å; K435-E453 PolarHBondContact NZ-OE2 3.07Å
436V98.1Very high95.6Very high0 Ų022.6 Ų22.60%011%0.113CC..EExtended strand (participates in β ladder)trans-123.4127.7178.3-169.80000109.8L406 V408 F425 V426 L430 M454L406-V436 HydrophobicContact CB-CG2 4.44Å; L406-V436 HydrophobicContact CD1-CG2 4.49Å; L406-V436 CarbonylContact O-C 3.59Å; L406-V436 WeakPolarHBondContact O-CA 3.34Å; V408-V436 HydrophobicContact CG1-CG1 4.42Å; F425-V436 HydrophobicContact CD1-CG1 4.14Å; F425-V436 HydrophobicContact CE1-CG1 4.08Å; V426-V436 HydrophobicContact CB-CG1 4.46Å; V426-V436 HydrophobicContact CG2-CB 4.48Å; V426-V436 HydrophobicContact CG2-CG1 3.82Å; L430-V436 HydrophobicContact CG-CG2 4.33Å; V436-M454 WeakPolarHBondContact O-CB 3.02Å; V436-M454 PolarHBondContact O-N 3.47Å
437Y98.6Very high95.7Very high24 Ų2424.2 Ų24.29%0.09412%0.121CC..EExtended strand (participates in β ladder)trans-106.9130.9175-68.7-85.4000110.3N405 L406 A407 V408 K435 L451 T452 E453 Y491 I493N405-Y437 HydrophobicContact CB-CD2 4.29Å; N405-Y437 HydrophobicContact CB-CE2 4.02Å; L406-Y437 PolarHBondContact O-N 2.74Å; A407-Y437 CarbonylContact C-O 3.6Å; A407-Y437 VanDerWaalsContact CA-O 3.27Å; A407-Y437 WeakPolarHBondContact CA-O 3.26Å; V408-Y437 PolarHBondContact N-O 3.18Å; K435-Y437 HydrophobicContact CB-CE2 4.25Å; Y437-L451 HydrophobicContact CD1-CB 4.45Å; Y437-T452 CarbonylContact C-O 3.55Å; Y437-T452 WeakPolarHBondContact CA-O 3.27Å; Y437-E453 HydrophobicContact CD1-CB 4.07Å; Y437-E453 HydrophobicContact CE1-CB 3.66Å; Y437-E453 HydrophobicContact CE1-CG 4.12Å; Y437-E453 PolarHBondContact OH-OE2 3.43Å; Y437-E453 VanDerWaalsContact OH-OE2 3.05Å; Y437-Y491 HydrophobicContact CD1-CD1 4.04Å; Y437-Y491 HydrophobicContact CD1-CE1 4.49Å; Y437-Y491 AromaticContact CE1-CD1 3.91Å; Y437-Y491 HydrophobicContact CE1-CD1 3.91Å; Y437-Y491 HydrophobicContact CE1-CE1 4.37Å; Y437-I493 HydrophobicContact CD2-CD1 3.85Å; Y437-I493 HydrophobicContact CG-CD1 4.32Å
438A98.4Very high95.8Very high1 Ų130 Ų301%0.00815%0.147CC..EExtended strand (participates in β ladder)trans-95.8124.6168.600000110L451 T452 M454 L470A438-L451 WeakPolarHBondContact O-CA 3.3Å; A438-T452 PolarHBondContact N-O 2.75Å; A438-T452 PolarHBondContact O-N 2.98Å; A438-M454 HydrophobicContact CB-CE 4.15Å; A438-M454 HydrophobicContact CB-CG 3.61Å; A438-M454 HydrophobicContact CB-SD 3.41Å; A438-M454 WeakPolarHBondContact CB-SD 3.47Å; A438-L470 HydrophobicContact CB-CD1 4Å; A438-L470 HydrophobicContact CB-CD2 3.63Å; A438-L470 HydrophobicContact CB-CG 4.49Å
439I98.6Very high95.9Very high0 Ų030.8 Ų30.80%016%0.155CC..EExtended strand (participates in β ladder)trans-91.1122.3176.2-61.7162.8000107.7A407 V408 M409 S442 L446 L451 L496A407-I439 HydrophobicContact CB-CD1 3.89Å; A407-I439 HydrophobicContact CB-CG1 4.48Å; V408-I439 PolarHBondContact O-N 3.46Å; M409-I439 HydrophobicContact CB-CB 3.73Å; M409-I439 HydrophobicContact CB-CD1 4.17Å; M409-I439 HydrophobicContact CB-CG1 4.47Å; M409-I439 HydrophobicContact CB-CG2 4.12Å; M409-I439 HydrophobicContact CE-CD1 3.63Å; M409-I439 HydrophobicContact SD-CD1 4.49Å; M409-I439 HydrophobicContact SD-CG2 4.45Å; I439-S442 WeakPolarHBondContact CG2-O 3.42Å; I439-L446 HydrophobicContact CD1-CD1 4.17Å; I439-L446 HydrophobicContact CD1-CD2 4.33Å; I439-L446 HydrophobicContact CG1-CD1 4.36Å; I439-L446 HydrophobicContact CG2-CB 3.75Å; I439-L446 HydrophobicContact CG2-CD1 4.35Å; I439-L446 HydrophobicContact CG2-CG 4.5Å; I439-L451 HydrophobicContact CD1-CD2 4.46Å; I439-L451 HydrophobicContact CG1-CD2 3.82Å; I439-L451 HydrophobicContact CG1-CG 3.82Å; I439-L496 HydrophobicContact CD1-CD1 4.04Å
440K97.8Very high96.1Very high92 Ų9235 Ų3540%0.417%0.173SC..SBendtrans-85.9149.9177.7-60.8-172178.8-177.40111.1S442 G445 K450 L470K440-S442 VanDerWaalsContact C-N 3.27Å; K440-S442 PolarHBondContact O-N 2.97Å; K440-G445 WeakPolarHBondContact O-CA 3.41Å; K440-K450 HydrophobicContact CB-CB 4.15Å; K440-K450 HydrophobicContact CB-CD 4.49Å; K440-K450 PolarHBondContact N-O 2.64Å; K440-L470 CarbonylContact C-O 3.57Å; K440-L470 WeakPolarHBondContact CA-O 3.19Å
441D97.1Very high96.3Very high47 Ų4734.3 Ų34.325%0.25117%0.169SC..SBendtrans54.735.9174.2-51.8-42.4000114.3Q444 G445 K450 L470D441-Q444 PolarHBondContact O-N 2.99Å; D441-G445 PolarHBondContact O-N 3.27Å; D441-K450 IonicContact OD2-NZ 2.8Å; D441-K450 PolarHBondContact OD2-NZ 3.08Å; D441-L470 PolarHBondContact N-O 2.57Å
442S97.7Very high96.6Very high0 Ų034.9 Ų34.90%018%0.178CC..Hα-helixtrans54.4-143.9177.3-450000112.5N410 I439 K440 Q444 G445 L446 Q473N410-S442 WeakPolarHBondContact O-CB 3.32Å; N410-S442 PolarHBondContact O-OG 3.28Å; I439-S442 WeakPolarHBondContact CG2-O 3.42Å; K440-S442 VanDerWaalsContact C-N 3.27Å; K440-S442 PolarHBondContact O-N 2.97Å; S442-Q444 VanDerWaalsContact C-N 3.29Å; S442-Q444 PolarHBondContact O-N 2.89Å; S442-G445 PolarHBondContact O-N 2.86Å; S442-L446 PolarHBondContact O-N 3.35Å; S442-Q473 PolarHBondContact OG-N 2.99Å; S442-Q473 PolarHBondContact OG-O 2.75Å
443F98.1Very high96.9Very high0 Ų039.3 Ų39.30%020%0.199CC..Hα-helixtrans-64.3-31.5178.8-68.4-80.5000113.3M409 V411 G445 L446 I447 S475 P477 M479 V484 L498 A507 L511M409-F443 HydrophobicContact CE-CD1 4.43Å; M409-F443 HydrophobicContact CE-CE1 3.85Å; M409-F443 HydrophobicContact CE-CZ 3.9Å; M409-F443 HydrophobicContact SD-CD1 4.45Å; M409-F443 HydrophobicContact SD-CD2 4.2Å; M409-F443 HydrophobicContact SD-CE1 4.2Å; M409-F443 HydrophobicContact SD-CE2 3.95Å; M409-F443 HydrophobicContact SD-CG 4.45Å; M409-F443 HydrophobicContact SD-CZ 3.95Å; V411-F443 HydrophobicContact CG1-CD2 4.45Å; V411-F443 HydrophobicContact CG1-CE2 4.28Å; V411-F443 HydrophobicContact CG2-CD2 4.4Å; V411-F443 HydrophobicContact CG2-CE2 3.96Å; F443-G445 VanDerWaalsContact C-N 3.31Å; F443-G445 PolarHBondContact O-N 2.95Å; F443-L446 HydrophobicContact CD1-CD2 4.11Å; F443-L446 HydrophobicContact CE1-CD2 4.38Å; F443-L446 PolarHBondContact O-N 3.37Å; F443-I447 WeakPolarHBondContact O-CD1 3.29Å; F443-I447 VanDerWaalsContact O-CG1 3.29Å; F443-I447 WeakPolarHBondContact O-CG1 3.44Å; F443-I447 PolarHBondContact O-N 3.32Å; F443-S475 VanDerWaalsContact CD2-O 3.27Å; F443-S475 WeakPolarHBondContact CD2-O 3.15Å; F443-S475 PolarHBondContact N-OG 3.1Å; F443-P477 HydrophobicContact CD1-CB 3.76Å; F443-P477 HydrophobicContact CD1-CG 4.36Å; F443-P477 HydrophobicContact CE1-CB 3.65Å; F443-P477 HydrophobicContact CE1-CG 3.93Å; F443-P477 HydrophobicContact CE2-CG 4.43Å; F443-P477 HydrophobicContact CG-CB 4.4Å; F443-P477 HydrophobicContact CZ-CB 4.2Å; F443-P477 HydrophobicContact CZ-CG 3.96Å; F443-M479 HydrophobicContact CB-SD 4.31Å; F443-V484 HydrophobicContact CD1-CG1 4.3Å; F443-V484 HydrophobicContact CD1-CG2 4.08Å; F443-V484 HydrophobicContact CE1-CG1 4.35Å; F443-L498 HydrophobicContact CE2-CD2 4.07Å; F443-L498 HydrophobicContact CZ-CD2 3.82Å; F443-A507 HydrophobicContact CD2-CB 4.48Å; F443-A507 HydrophobicContact CE2-CB 3.42Å; F443-A507 VanDerWaalsContact CE2-CB 3.42Å; F443-A507 HydrophobicContact CZ-CB 3.68Å; F443-L511 HydrophobicContact CE1-CD1 4.23Å; F443-L511 HydrophobicContact CZ-CD1 4.19Å
444Q96.9Very high97.3Very high81 Ų8138.3 Ų38.338%0.37918%0.184SC..Hα-helixtrans-64.1-37.2177.8-167.7179.61900112.3D441 S442 K448 M479D441-Q444 PolarHBondContact O-N 2.99Å; S442-Q444 VanDerWaalsContact C-N 3.29Å; S442-Q444 PolarHBondContact O-N 2.89Å; Q444-K448 WeakPolarHBondContact O-CG 3.46Å; Q444-M479 HydrophobicContact CB-CE 4.43Å; Q444-M479 HydrophobicContact CG-CE 4.31Å
445G97.2Very high97.3Very high0 Ų041 Ų410%020%0.203CC..Hα-helixtrans-81.2-31.9172.900000113.2K440 D441 S442 F443 I447 K448 G449 K450K440-G445 WeakPolarHBondContact O-CA 3.41Å; D441-G445 PolarHBondContact O-N 3.27Å; S442-G445 PolarHBondContact O-N 2.86Å; F443-G445 VanDerWaalsContact C-N 3.31Å; F443-G445 PolarHBondContact O-N 2.95Å; G445-I447 PolarHBondContact O-N 3.19Å; G445-K448 CarbonylContact O-C 3.47Å; G445-K448 WeakPolarHBondContact O-CA 3.35Å; G445-K448 PolarHBondContact O-N 3.05Å; G445-K448 VanDerWaalsContact O-N 3.09Å; G445-G449 PolarHBondContact O-N 3.31Å; G445-K450 WeakPolarHBondContact O-CB 3.29Å; G445-K450 PolarHBondContact O-N 2.94Å
446L97.8Very high97Very high0 Ų037.4 Ų37.40%019%0.187CC..Hα-helixtrans-56.2-50.2172.4-178.851.6000111.7M409 I439 S442 F443 K448 G449 L451 V484 Q487 L488M409-L446 HydrophobicContact CE-CD2 4.02Å; I439-L446 HydrophobicContact CD1-CD1 4.17Å; I439-L446 HydrophobicContact CD1-CD2 4.33Å; I439-L446 HydrophobicContact CG1-CD1 4.36Å; I439-L446 HydrophobicContact CG2-CB 3.75Å; I439-L446 HydrophobicContact CG2-CD1 4.35Å; I439-L446 HydrophobicContact CG2-CG 4.5Å; S442-L446 PolarHBondContact O-N 3.35Å; F443-L446 HydrophobicContact CD1-CD2 4.11Å; F443-L446 HydrophobicContact CE1-CD2 4.38Å; F443-L446 PolarHBondContact O-N 3.37Å; L446-K448 PolarHBondContact O-N 3.13Å; L446-K448 VanDerWaalsContact O-N 3.13Å; L446-G449 WeakPolarHBondContact O-CA 3.46Å; L446-G449 PolarHBondContact O-N 3.41Å; L446-L451 HydrophobicContact CD1-CD1 3.74Å; L446-L451 HydrophobicContact CD1-CD2 4.35Å; L446-L451 HydrophobicContact CD1-CG 4.39Å; L446-V484 HydrophobicContact CD2-CG1 3.81Å; L446-Q487 HydrophobicContact CD1-CB 3.87Å; L446-Q487 HydrophobicContact CG-CB 4.45Å; L446-Q487 VanDerWaalsContact O-CG 3.31Å; L446-Q487 WeakPolarHBondContact O-CG 3.19Å; L446-L488 HydrophobicContact CD2-CD2 4.33Å
447I97.3Very high96.5Very high34 Ų3440 Ų4017%0.17420%0.199CC..Hα-helixtrans-57.3-30.4177.9-71.4160.8000111.8F443 G445 G449 M479 N480 A483 V484F443-I447 WeakPolarHBondContact O-CD1 3.29Å; F443-I447 VanDerWaalsContact O-CG1 3.29Å; F443-I447 WeakPolarHBondContact O-CG1 3.44Å; F443-I447 PolarHBondContact O-N 3.32Å; G445-I447 PolarHBondContact O-N 3.19Å; I447-G449 VanDerWaalsContact C-N 3.31Å; I447-M479 HydrophobicContact CD1-CE 3.91Å; I447-M479 HydrophobicContact CD1-CG 3.34Å; I447-M479 HydrophobicContact CD1-SD 3.52Å; I447-M479 VanDerWaalsContact CD1-SD 3.52Å; I447-N480 HydrophobicContact CD1-CB 3.83Å; I447-N480 HydrophobicContact CG1-CB 4.36Å; I447-A483 HydrophobicContact CB-CB 4.42Å; I447-A483 HydrophobicContact CG1-CB 4.2Å; I447-A483 HydrophobicContact CG2-CB 3.86Å; I447-V484 HydrophobicContact CD1-CG2 4.14Å; I447-V484 HydrophobicContact CG1-CG2 3.74Å
448K96.8Very high96.2Very high136 Ų13640.9 Ų40.959%0.59121%0.209SC*.THydrogen-bonded Turntrans-87.14.3177-64.1175.7-176.1179.60113.3Q444 G445 L446 K450Q444-K448 WeakPolarHBondContact O-CG 3.46Å; G445-K448 CarbonylContact O-C 3.47Å; G445-K448 WeakPolarHBondContact O-CA 3.35Å; G445-K448 PolarHBondContact O-N 3.05Å; G445-K448 VanDerWaalsContact O-N 3.09Å; L446-K448 PolarHBondContact O-N 3.13Å; L446-K448 VanDerWaalsContact O-N 3.13Å; K448-K450 HydrophobicContact CB-CG 4.26Å; K448-K450 PolarHBondContact O-N 3.23Å
449G95.8Very high95.9Very high16 Ų1640.9 Ų40.917%0.16521%0.208CC..THydrogen-bonded Turntrans70.125-178.100000114.4G445 L446 I447 L451 Y491G445-G449 PolarHBondContact O-N 3.31Å; L446-G449 WeakPolarHBondContact O-CA 3.46Å; L446-G449 PolarHBondContact O-N 3.41Å; I447-G449 VanDerWaalsContact C-N 3.31Å; G449-L451 VanDerWaalsContact C-N 3.26Å; G449-L451 PolarHBondContact O-N 3.41Å; G449-Y491 PolarHBondContact O-OH 3.26Å
450K97.5Very high95.4Very high89 Ų8942.5 Ų42.539%0.38722%0.217SC..  trans-80.566.1-179.1-63.8-170.3-179-176.10112.7K440 D441 G445 K448K440-K450 HydrophobicContact CB-CB 4.15Å; K440-K450 HydrophobicContact CB-CD 4.49Å; K440-K450 PolarHBondContact N-O 2.64Å; D441-K450 IonicContact OD2-NZ 2.8Å; D441-K450 PolarHBondContact OD2-NZ 3.08Å; G445-K450 WeakPolarHBondContact O-CB 3.29Å; G445-K450 PolarHBondContact O-N 2.94Å; K448-K450 HydrophobicContact CB-CG 4.26Å; K448-K450 PolarHBondContact O-N 3.23Å
451L97.3Very high94.9Very high17 Ų1741.4 Ų41.49%0.08922%0.215CC..EExtended strand (participates in β ladder)trans-106.4142.6173.1-64.481.3000110.8Y437 A438 I439 L446 G449 Y491 I493Y437-L451 HydrophobicContact CD1-CB 4.45Å; A438-L451 WeakPolarHBondContact O-CA 3.3Å; I439-L451 HydrophobicContact CD1-CD2 4.46Å; I439-L451 HydrophobicContact CG1-CD2 3.82Å; I439-L451 HydrophobicContact CG1-CG 3.82Å; L446-L451 HydrophobicContact CD1-CD1 3.74Å; L446-L451 HydrophobicContact CD1-CD2 4.35Å; L446-L451 HydrophobicContact CD1-CG 4.39Å; G449-L451 VanDerWaalsContact C-N 3.26Å; G449-L451 PolarHBondContact O-N 3.41Å; L451-Y491 HydrophobicContact CB-CD1 4.15Å; L451-Y491 HydrophobicContact CB-CE1 3.81Å; L451-Y491 HydrophobicContact CB-CE2 4.23Å; L451-Y491 HydrophobicContact CB-CG 4.48Å; L451-Y491 HydrophobicContact CD1-CD2 3.94Å; L451-Y491 HydrophobicContact CD1-CE2 3.67Å; L451-Y491 HydrophobicContact CD2-CD1 4.22Å; L451-Y491 HydrophobicContact CD2-CD2 3.91Å; L451-Y491 HydrophobicContact CD2-CE2 4.36Å; L451-Y491 HydrophobicContact CD2-CG 3.84Å; L451-Y491 HydrophobicContact CG-CD2 4.32Å; L451-Y491 HydrophobicContact CG-CE2 4.28Å; L451-I493 HydrophobicContact CD2-CD1 4.48Å
452T97.6Very high94.7Very high59 Ų5940.8 Ų40.836%0.36221%0.209SC..EExtended strand (participates in β ladder)trans-127.5127.5176-54.10000109.5Y437 A438 M454Y437-T452 CarbonylContact C-O 3.55Å; Y437-T452 WeakPolarHBondContact CA-O 3.27Å; A438-T452 PolarHBondContact N-O 2.75Å; A438-T452 PolarHBondContact O-N 2.98Å; T452-M454 PolarHBondContact O-N 3.24Å
453E97.9Very high94.5Very high99 Ų9940.9 Ų40.946%0.46321%0.21SC..EExtended strand (participates in β ladder)trans-68.1125172.6-170.6167.3158.600109.1K435 Y437K435-E453 WeakPolarHBondContact CE-OE1 3.46Å; K435-E453 IonicContact NZ-OE1 2.66Å; K435-E453 PolarHBondContact NZ-OE1 3.19Å; K435-E453 IonicContact NZ-OE2 3.93Å; K435-E453 PolarHBondContact NZ-OE2 3.07Å; Y437-E453 HydrophobicContact CD1-CB 4.07Å; Y437-E453 HydrophobicContact CE1-CB 3.66Å; Y437-E453 HydrophobicContact CE1-CG 4.12Å; Y437-E453 PolarHBondContact OH-OE2 3.43Å; Y437-E453 VanDerWaalsContact OH-OE2 3.05Å
454M97Very high94.2Very high17 Ų1742.4 Ų42.48%0.08422%0.216CC..EExtended strand (participates in β ladder)trans-93.7142.1-175.2-57.7-59-7700110.5V426 V436 A438 T452 S458 V459 W462V426-M454 HydrophobicContact CG1-CB 3.7Å; V426-M454 HydrophobicContact CG2-CB 4.04Å; V426-M454 HydrophobicContact CG2-CG 4.07Å; V436-M454 WeakPolarHBondContact O-CB 3.02Å; V436-M454 PolarHBondContact O-N 3.47Å; A438-M454 HydrophobicContact CB-CE 4.15Å; A438-M454 HydrophobicContact CB-CG 3.61Å; A438-M454 HydrophobicContact CB-SD 3.41Å; A438-M454 WeakPolarHBondContact CB-SD 3.47Å; T452-M454 PolarHBondContact O-N 3.24Å; M454-S458 WeakPolarHBondContact CE-OG 3.33Å; M454-V459 HydrophobicContact CE-CG1 3.54Å; M454-W462 HydrophobicContact CE-CH2 4.11Å; M454-W462 HydrophobicContact CE-CZ2 4.36Å
455S93.8Very high94Very high61 Ų6142.6 Ų42.643%0.42721%0.213SC..  trans-110.1164.6172.876.30000111H457 S458S455-H457 PolarHBondContact O-N 3.44Å; S455-H457 VanDerWaalsContact O-N 3.11Å; S455-S458 PolarHBondContact N-OG 2.84Å; S455-S458 PolarHBondContact O-N 3.13Å; S455-S458 PolarHBondContact O-OG 3.38Å; S455-S458 PolarHBondContact OG-N 3.09Å
456W89.5Confident93.9Very high12 Ų1243.4 Ų43.45%0.04522%0.222CC..THydrogen-bonded Turntrans-53.2-36.5178.2-168.5-91.6000112.8K388 M389 P391 R427 L430K388-W456 HydrophobicContact CB-CZ2 4.37Å; K388-W456 VanDerWaalsContact O-CZ2 3.3Å; K388-W456 WeakPolarHBondContact O-CZ2 3.42Å; K388-W456 PolarHBondContact O-NE1 3.46Å; M389-W456 PolarHBondContact O-NE1 3.29Å; P391-W456 HydrophobicContact CB-CE3 3.81Å; P391-W456 HydrophobicContact CB-CZ3 3.8Å; P391-W456 HydrophobicContact CG-CE3 4.17Å; R427-W456 HydrophobicContact CB-CE3 4.35Å; R427-W456 HydrophobicContact CB-CH2 4.09Å; R427-W456 HydrophobicContact CB-CZ2 4.47Å; R427-W456 HydrophobicContact CB-CZ3 4.04Å; R427-W456 HydrophobicContact CG-CD2 4.21Å; R427-W456 HydrophobicContact CG-CE3 4.27Å; R427-W456 HydrophobicContact CG-CH2 4.4Å; R427-W456 HydrophobicContact CG-CZ2 4.32Å; R427-W456 HydrophobicContact CG-CZ3 4.38Å; R427-W456 WeakPolarHBondContact O-CZ3 3.46Å; L430-W456 HydrophobicContact CB-CE3 3.95Å; L430-W456 HydrophobicContact CB-CZ3 4.3Å; L430-W456 HydrophobicContact CD1-CB 4.16Å; L430-W456 HydrophobicContact CD1-CE3 4.24Å
457H89Confident93.7Very high55 Ų5544.8 Ų44.826%0.25524%0.236SC..THydrogen-bonded Turntrans-87.5-19.3-176.6-58.889.4000113.2Y248 S455 V459 I460Y248-H457 AromaticContact CD1-CE1 3.58Å; Y248-H457 AromaticContact CD1-NE2 3.47Å; Y248-H457 WeakPolarHBondContact CD1-NE2 3.34Å; Y248-H457 AromaticContact CE1-CE1 3.93Å; Y248-H457 AromaticContact CG-NE2 3.54Å; S455-H457 PolarHBondContact O-N 3.44Å; S455-H457 VanDerWaalsContact O-N 3.11Å; H457-V459 PolarHBondContact O-N 3.36Å; H457-V459 VanDerWaalsContact O-N 3.14Å; H457-I460 HydrophobicContact CB-CD1 3.89Å; H457-I460 WeakPolarHBondContact O-CG1 3.28Å; H457-I460 PolarHBondContact O-N 2.95Å
458S91.2Very high93.7Very high43 Ų4344.4 Ų44.430%0.30124%0.236SC..THydrogen-bonded Turntrans-64.9-17.9-177.766.10000114.5M454 S455 W462M454-S458 WeakPolarHBondContact CE-OG 3.33Å; S455-S458 PolarHBondContact N-OG 2.84Å; S455-S458 PolarHBondContact O-N 3.13Å; S455-S458 PolarHBondContact O-OG 3.38Å; S455-S458 PolarHBondContact OG-N 3.09Å; S458-W462 PolarHBondContact O-NE1 2.91Å
459V92.9Very high93.7Very high0 Ų042.5 Ų42.50%023%0.228CC..THydrogen-bonded Turntrans-113.116.8-177-63.90000113.6R423 V426 R427 M454 H457 W462R423-V459 HydrophobicContact CB-CB 3.98Å; R423-V459 HydrophobicContact CB-CG2 4.28Å; R423-V459 WeakPolarHBondContact CD-O 3.17Å; R423-V459 HydrophobicContact CG-CB 3.91Å; R423-V459 HydrophobicContact CG-CG2 3.8Å; R423-V459 WeakPolarHBondContact CG-O 3.28Å; V426-V459 HydrophobicContact CB-CG1 4.11Å; V426-V459 HydrophobicContact CB-CG2 4.27Å; V426-V459 HydrophobicContact CG1-CG1 4.06Å; V426-V459 HydrophobicContact CG1-CG2 4.03Å; V426-V459 HydrophobicContact CG2-CG1 4.1Å; R427-V459 HydrophobicContact CG-CG2 4.22Å; M454-V459 HydrophobicContact CE-CG1 3.54Å; H457-V459 PolarHBondContact O-N 3.36Å; H457-V459 VanDerWaalsContact O-N 3.14Å; V459-W462 HydrophobicContact CB-CD2 4.2Å; V459-W462 HydrophobicContact CB-CG 4.28Å; V459-W462 HydrophobicContact CG1-CD2 4.2Å; V459-W462 HydrophobicContact CG1-CE3 4.32Å; V459-W462 HydrophobicContact CG1-CZ2 4.45Å
460I88.2Confident93.7Very high35 Ų3542 Ų4218%0.17922%0.222CC..THydrogen-bonded Turntrans-64.2138175.2-73170.9000110.2Q250 H457 W462Q250-I460 HydrophobicContact CG-CD1 4.12Å; H457-I460 HydrophobicContact CB-CD1 3.89Å; H457-I460 WeakPolarHBondContact O-CG1 3.28Å; H457-I460 PolarHBondContact O-N 2.95Å; I460-W462 VanDerWaalsContact O-CD1 3.23Å; I460-W462 PolarHBondContact O-N 3.27Å
461D86.9Confident93.7Very high68 Ų6838.8 Ų38.836%0.36421%0.213SC..THydrogen-bonded Turntrans65.816.1177.9-57.4-27.8000115.1E219 Y465E219-D461 WeakPolarHBondContact OE1-CA 3.29Å; E219-D461 PolarHBondContact OE1-N 3.17Å; E219-D461 PolarHBondContact OE2-N 3.17Å; D461-Y465 WeakPolarHBondContact O-CD2 3.49Å; D461-Y465 WeakPolarHBondContact O-CE2 3.42Å
462W93.5Very high93.6Very high35 Ų3538.7 Ų38.713%0.13322%0.215CC..  trans-75.5-24.9178.6-78.434.9000112.7E219 N419 V422 R423 M454 S458 V459 I460 R464 Y465 F469 L470E219-W462 PolarHBondContact OE1-N 3.41Å; N419-W462 HydrophobicContact CB-CB 4.21Å; N419-W462 HydrophobicContact CB-CE3 4.31Å; N419-W462 WeakPolarHBondContact CB-O 3.49Å; V422-W462 HydrophobicContact CB-CE3 4.43Å; V422-W462 HydrophobicContact CB-CZ3 4.34Å; V422-W462 HydrophobicContact CG1-CE3 4.15Å; V422-W462 HydrophobicContact CG1-CZ3 3.72Å; R423-W462 HydrophobicContact CB-CB 4.04Å; M454-W462 HydrophobicContact CE-CH2 4.11Å; M454-W462 HydrophobicContact CE-CZ2 4.36Å; S458-W462 PolarHBondContact O-NE1 2.91Å; V459-W462 HydrophobicContact CB-CD2 4.2Å; V459-W462 HydrophobicContact CB-CG 4.28Å; V459-W462 HydrophobicContact CG1-CD2 4.2Å; V459-W462 HydrophobicContact CG1-CE3 4.32Å; V459-W462 HydrophobicContact CG1-CZ2 4.45Å; I460-W462 VanDerWaalsContact O-CD1 3.23Å; I460-W462 PolarHBondContact O-N 3.27Å; W462-R464 VanDerWaalsContact C-N 3.3Å; W462-R464 PolarHBondContact O-N 3.04Å; W462-Y465 PolarHBondContact O-N 2.8Å; W462-F469 HydrophobicContact CB-CE2 4.43Å; W462-F469 AromaticContact CD1-CD2 3.92Å; W462-F469 AromaticContact CD1-CE2 3.87Å; W462-F469 AromaticContact CD2-CD2 3.49Å; W462-F469 HydrophobicContact CD2-CD2 3.49Å; W462-F469 VanDerWaalsContact CD2-CD2 3.49Å; W462-F469 HydrophobicContact CD2-CE2 4.14Å; W462-F469 AromaticContact CE2-CD2 3.55Å; W462-F469 HydrophobicContact CE3-CB 4.3Å; W462-F469 AromaticContact CE3-CD2 3.85Å; W462-F469 HydrophobicContact CE3-CD2 3.85Å; W462-F469 AromaticContact CG-CD2 3.77Å; W462-F469 HydrophobicContact CG-CD2 3.77Å; W462-F469 AromaticContact CG-CE2 3.92Å; W462-F469 HydrophobicContact CG-CE2 3.92Å; W462-F469 HydrophobicContact CH2-CB 3.73Å; W462-F469 HydrophobicContact CH2-CD2 4.31Å; W462-F469 HydrophobicContact CZ2-CB 4.06Å; W462-F469 AromaticContact CZ2-CD2 4Å; W462-F469 HydrophobicContact CZ2-CD2 4Å; W462-F469 HydrophobicContact CZ3-CB 3.85Å; W462-F469 HydrophobicContact CZ3-CD2 4.23Å; W462-F469 AromaticContact NE1-CD2 3.84Å; W462-L470 HydrophobicContact CH2-CD2 3.78Å; W462-L470 HydrophobicContact CZ3-CD2 4.04Å; W462-L470 HydrophobicContact CZ3-CG 4.3Å
463T92.9Very high93.5Very high1 Ų139.9 Ų39.91%0.00622%0.216CC..THydrogen-bonded Turntrans-62-35.8-168.6-53.40000112.8V217 E219 A420 R423 R676V217-T463 WeakPolarHBondContact O-CG2 3.21Å; E219-T463 VanDerWaalsContact CD-OG1 3.26Å; E219-T463 WeakPolarHBondContact CG-OG1 3.26Å; E219-T463 WeakPolarHBondContact OE1-CB 3.37Å; E219-T463 PolarHBondContact OE1-N 2.94Å; E219-T463 PolarHBondContact OE1-OG1 2.8Å; A420-T463 HydrophobicContact CB-CG2 3.91Å; R423-T463 WeakPolarHBondContact CD-OG1 3.4Å; R423-T463 PolarHBondContact NE-OG1 3.06Å; T463-R676 HydrophobicContact CG2-CB 4Å; T463-R676 HydrophobicContact CG2-CG 4.08Å
464R91.5Very high93.4Very high33 Ų3340.9 Ų40.913%0.12522%0.219CC..THydrogen-bonded Turntrans-74.9-34-173.469.1178.8178.4-173.9-5.5114.6W462 N670 A671W462-R464 VanDerWaalsContact C-N 3.3Å; W462-R464 PolarHBondContact O-N 3.04Å; R464-N670 WeakPolarHBondContact O-CA 3.3Å; R464-N670 WeakPolarHBondContact O-CB 3.17Å; R464-A671 PolarHBondContact O-N 3.35Å; R464-A671 VanDerWaalsContact O-N 3.11Å
465Y93.3Very high93.3Very high84 Ų8441 Ų4133%0.32922%0.222SC..BIsolated β-bridgetrans-80.3133.6-166.2-67.1-75.2000111.6N419 D461 W462 F469N419-Y465 PolarHBondContact ND2-O 3.23Å; D461-Y465 WeakPolarHBondContact O-CD2 3.49Å; D461-Y465 WeakPolarHBondContact O-CE2 3.42Å; W462-Y465 PolarHBondContact O-N 2.8Å; Y465-F469 HydrophobicContact CD1-CZ 4.46Å; Y465-F469 AromaticContact CD2-CE2 3.94Å; Y465-F469 HydrophobicContact CD2-CE2 3.94Å; Y465-F469 AromaticContact CD2-CZ 3.52Å; Y465-F469 HydrophobicContact CD2-CZ 3.52Å; Y465-F469 HydrophobicContact CE2-CZ 4.19Å; Y465-F469 HydrophobicContact CG-CE1 4.46Å; Y465-F469 HydrophobicContact CG-CE2 4.39Å; Y465-F469 AromaticContact CG-CZ 3.65Å; Y465-F469 HydrophobicContact CG-CZ 3.65Å
466G93.3Very high93.5Very high18 Ų1839.9 Ų39.919%0.18621%0.211CC..  trans-71.7-174.4163.900000112.7N419 G669N419-G466 PolarHBondContact ND2-O 2.93Å; G466-G669 WeakPolarHBondContact CA-O 3.28Å; G466-G669 PolarHBondContact N-O 3.39Å
467G94.5Very high93.8Very high29 Ų2939.3 Ų39.330%0.29921%0.208SC..SBendtrans70.3-154.8-175.700000113.1N419N419-G467 PolarHBondContact ND2-O 2.97Å
468S96.8Very high94.2Very high25 Ų2539.9 Ų39.918%0.17522%0.219CC..  trans-140.3114.3-179.4175.50000111N410 N419 L470 G471N410-S468 PolarHBondContact ND2-OG 3.22Å; N419-S468 WeakPolarHBondContact OD1-CA 3.31Å; S468-L470 VanDerWaalsContact C-N 3.26Å; S468-L470 PolarHBondContact O-N 2.92Å; S468-L470 PolarHBondContact OG-N 3.32Å; S468-G471 PolarHBondContact O-N 2.78Å; S468-G471 VanDerWaalsContact O-N 3.13Å; S468-G471 PolarHBondContact OG-N 2.92Å; S468-G471 PolarHBondContact OG-O 2.9Å
469F96.9Very high94.4Very high97 Ų9742.6 Ų42.643%0.42523%0.227SC..THydrogen-bonded Turntrans-71.6-20.7173.6-67.7-22.6000113.7N419 W462 Y465N419-F469 PolarHBondContact OD1-N 3.26Å; W462-F469 HydrophobicContact CB-CE2 4.43Å; W462-F469 AromaticContact CD1-CD2 3.92Å; W462-F469 AromaticContact CD1-CE2 3.87Å; W462-F469 AromaticContact CD2-CD2 3.49Å; W462-F469 HydrophobicContact CD2-CD2 3.49Å; W462-F469 VanDerWaalsContact CD2-CD2 3.49Å; W462-F469 HydrophobicContact CD2-CE2 4.14Å; W462-F469 AromaticContact CE2-CD2 3.55Å; W462-F469 HydrophobicContact CE3-CB 4.3Å; W462-F469 AromaticContact CE3-CD2 3.85Å; W462-F469 HydrophobicContact CE3-CD2 3.85Å; W462-F469 AromaticContact CG-CD2 3.77Å; W462-F469 HydrophobicContact CG-CD2 3.77Å; W462-F469 AromaticContact CG-CE2 3.92Å; W462-F469 HydrophobicContact CG-CE2 3.92Å; W462-F469 HydrophobicContact CH2-CB 3.73Å; W462-F469 HydrophobicContact CH2-CD2 4.31Å; W462-F469 HydrophobicContact CZ2-CB 4.06Å; W462-F469 AromaticContact CZ2-CD2 4Å; W462-F469 HydrophobicContact CZ2-CD2 4Å; W462-F469 HydrophobicContact CZ3-CB 3.85Å; W462-F469 HydrophobicContact CZ3-CD2 4.23Å; W462-F469 AromaticContact NE1-CD2 3.84Å; Y465-F469 HydrophobicContact CD1-CZ 4.46Å; Y465-F469 AromaticContact CD2-CE2 3.94Å; Y465-F469 HydrophobicContact CD2-CE2 3.94Å; Y465-F469 AromaticContact CD2-CZ 3.52Å; Y465-F469 HydrophobicContact CD2-CZ 3.52Å; Y465-F469 HydrophobicContact CE2-CZ 4.19Å; Y465-F469 HydrophobicContact CG-CE1 4.46Å; Y465-F469 HydrophobicContact CG-CE2 4.39Å; Y465-F469 AromaticContact CG-CZ 3.65Å; Y465-F469 HydrophobicContact CG-CZ 3.65Å
470L97.1Very high94.6Very high6 Ų645.9 Ų45.93%0.03125%0.245CC..THydrogen-bonded Turntrans-80.9-7.1171.4-58.2-169.1000112.3V408 V422 A438 K440 D441 W462 S468V408-L470 HydrophobicContact CG1-CD1 4.48Å; V422-L470 HydrophobicContact CG1-CD1 3.92Å; V422-L470 HydrophobicContact CG1-CG 4.42Å; V422-L470 HydrophobicContact CG2-CD1 3.94Å; A438-L470 HydrophobicContact CB-CD1 4Å; A438-L470 HydrophobicContact CB-CD2 3.63Å; A438-L470 HydrophobicContact CB-CG 4.49Å; K440-L470 CarbonylContact C-O 3.57Å; K440-L470 WeakPolarHBondContact CA-O 3.19Å; D441-L470 PolarHBondContact N-O 2.57Å; W462-L470 HydrophobicContact CH2-CD2 3.78Å; W462-L470 HydrophobicContact CZ3-CD2 4.04Å; W462-L470 HydrophobicContact CZ3-CG 4.3Å; S468-L470 VanDerWaalsContact C-N 3.26Å; S468-L470 PolarHBondContact O-N 2.92Å; S468-L470 PolarHBondContact OG-N 3.32Å
471G96.6Very high95Very high20 Ų2045.2 Ų45.221%0.20624%0.242CC..  trans74154.7-160.800000110.7S468S468-G471 PolarHBondContact O-N 2.78Å; S468-G471 VanDerWaalsContact O-N 3.13Å; S468-G471 PolarHBondContact OG-N 2.92Å; S468-G471 PolarHBondContact OG-O 2.9Å
472S95.9Very high95.6Very high16 Ų1645.6 Ų45.611%0.11225%0.248CC..  trans-147.5121.7177.7-169.50000108.7G412G412-S472 CarbonylContact O-C 3.58Å; G412-S472 WeakPolarHBondContact O-CB 3.38Å; G412-S472 PolarHBondContact O-OG 3.24Å
473Q95.9Very high95.8Very high83 Ų8344.5 Ų44.539%0.38825%0.246SC..BIsolated β-bridgetrans-126.5153.8-177.3-59.7-63.1-20.300110.1G412 S442 S475G412-Q473 PolarHBondContact N-O 3.42Å; S442-Q473 PolarHBondContact OG-N 2.99Å; S442-Q473 PolarHBondContact OG-O 2.75Å; Q473-S475 PolarHBondContact O-N 3.47Å
474K95.1Very high96Very high120 Ų12044.4 Ų44.452%0.52225%0.246SC..  trans-80.712.2175.6-64.1-176.7176.5-177.50113.7S413 E503S413-K474 WeakPolarHBondContact OG-CE 3.4Å; K474-E503 HydrophobicContact CB-CG 4.07Å; K474-E503 HydrophobicContact CG-CG 4.35Å
475S94.7Very high96.3Very high21 Ų2143 Ų4315%0.14724%0.241CC..  trans-66.1139.818056.20000111.4F443 Q473F443-S475 VanDerWaalsContact CD2-O 3.27Å; F443-S475 WeakPolarHBondContact CD2-O 3.15Å; F443-S475 PolarHBondContact N-OG 3.1Å; Q473-S475 PolarHBondContact O-N 3.47Å
476L96.9Very high96.6Very high37 Ų3744.9 Ų44.919%0.19425%0.253CS..  trans-105.6156.4174.2-65.5176.1000110.8S478 M479 E503 H506 A507L476-S478 WeakPolarHBondContact CB-OG 3.38Å; L476-S478 PolarHBondContact O-N 2.81Å; L476-M479 WeakPolarHBondContact O-CG 3.47Å; L476-M479 PolarHBondContact O-N 2.94Å; L476-E503 HydrophobicContact CD2-CB 4.28Å; L476-E503 WeakPolarHBondContact CD2-O 3.4Å; L476-H506 HydrophobicContact CD2-CB 4.26Å; L476-A507 HydrophobicContact CD2-CB 4.07Å
477P97.2Very high96.8Very high0 Ų044.7 Ų44.70%025%0.247CC..G310 helixtrans-62.4-28.1178.318.8-25.2000113.1F443 M479 N480 M481 V484 A507 E510 L511F443-P477 HydrophobicContact CD1-CB 3.76Å; F443-P477 HydrophobicContact CD1-CG 4.36Å; F443-P477 HydrophobicContact CE1-CB 3.65Å; F443-P477 HydrophobicContact CE1-CG 3.93Å; F443-P477 HydrophobicContact CE2-CG 4.43Å; F443-P477 HydrophobicContact CG-CB 4.4Å; F443-P477 HydrophobicContact CZ-CB 4.2Å; F443-P477 HydrophobicContact CZ-CG 3.96Å; P477-M479 PolarHBondContact O-N 3.24Å; P477-N480 CarbonylContact O-C 3.58Å; P477-N480 PolarHBondContact O-N 2.51Å; P477-N480 VanDerWaalsContact O-N 3.08Å; P477-M481 HydrophobicContact CB-CE 4.45Å; P477-M481 HydrophobicContact CB-SD 4.38Å; P477-M481 PolarHBondContact O-N 2.96Å; P477-V484 HydrophobicContact CB-CG2 4.35Å; P477-A507 HydrophobicContact CG-CB 4.08Å; P477-E510 WeakPolarHBondContact CD-OE2 3.33Å; P477-E510 HydrophobicContact CG-CB 3.91Å; P477-E510 VanDerWaalsContact CG-OE2 3.26Å; P477-E510 WeakPolarHBondContact CG-OE2 3.49Å; P477-L511 HydrophobicContact CB-CD2 3.83Å; P477-L511 HydrophobicContact CB-CG 4.32Å; P477-L511 HydrophobicContact CG-CD2 4.03Å; P477-L511 HydrophobicContact CG-CG 3.96Å
478S96.3Very high96.9Very high67 Ų6743.5 Ų43.547%0.46923%0.234SC..G310 helixtrans-53-19.3173.7490000115L476 N480 E510L476-S478 WeakPolarHBondContact CB-OG 3.38Å; L476-S478 PolarHBondContact O-N 2.81Å; S478-N480 VanDerWaalsContact C-N 3.26Å; S478-N480 PolarHBondContact O-N 3.23Å; S478-E510 WeakPolarHBondContact CB-OE1 3.2Å; S478-E510 WeakPolarHBondContact CB-OE2 3.21Å; S478-E510 PolarHBondContact N-OE2 3.12Å; S478-E510 VanDerWaalsContact OG-CD 3.32Å; S478-E510 PolarHBondContact OG-OE1 3Å; S478-E510 PolarHBondContact OG-OE2 3.48Å
479M95.9Very high97Very high99 Ų9943.8 Ų43.849%0.48824%0.241SC..G310 helixtrans-61.2-32.6175.174.2-176.8-70.600113.5F443 Q444 I447 L476 P477F443-M479 HydrophobicContact CB-SD 4.31Å; Q444-M479 HydrophobicContact CB-CE 4.43Å; Q444-M479 HydrophobicContact CG-CE 4.31Å; I447-M479 HydrophobicContact CD1-CE 3.91Å; I447-M479 HydrophobicContact CD1-CG 3.34Å; I447-M479 HydrophobicContact CD1-SD 3.52Å; I447-M479 VanDerWaalsContact CD1-SD 3.52Å; L476-M479 WeakPolarHBondContact O-CG 3.47Å; L476-M479 PolarHBondContact O-N 2.94Å; P477-M479 PolarHBondContact O-N 3.24Å
480N97.2Very high97Very high69 Ų6947.7 Ų47.737%0.36925%0.252SS..  trans-165.976.4172.5-167.5-25.5000110.3I447 P477 S478 P482 A483 V484I447-N480 HydrophobicContact CD1-CB 3.83Å; I447-N480 HydrophobicContact CG1-CB 4.36Å; P477-N480 CarbonylContact O-C 3.58Å; P477-N480 PolarHBondContact O-N 2.51Å; P477-N480 VanDerWaalsContact O-N 3.08Å; S478-N480 VanDerWaalsContact C-N 3.26Å; S478-N480 PolarHBondContact O-N 3.23Å; N480-P482 WeakPolarHBondContact OD1-CD 3.29Å; N480-A483 HydrophobicContact CB-CB 4.18Å; N480-A483 VanDerWaalsContact CG-CB 3.48Å; N480-A483 PolarHBondContact O-N 3.48Å; N480-A483 WeakPolarHBondContact OD1-CB 3.29Å; N480-A483 PolarHBondContact OD1-N 3.4Å; N480-A483 VanDerWaalsContact OD1-N 3.13Å; N480-V484 WeakPolarHBondContact O-CG2 3.07Å; N480-V484 PolarHBondContact O-N 3.28Å; N480-V484 VanDerWaalsContact O-N 3.11Å
481M97.2Very high97Very high22 Ų2250 Ų5011%0.10826%0.261CS..Hα-helixtrans-51.6-47.7179.2-82.9-85.5-166.300113.8P477 A483 V484 A485 E510 N514 F518 F521P477-M481 HydrophobicContact CB-CE 4.45Å; P477-M481 HydrophobicContact CB-SD 4.38Å; P477-M481 PolarHBondContact O-N 2.96Å; M481-A483 PolarHBondContact O-N 3.42Å; M481-V484 WeakPolarHBondContact O-CB 3.41Å; M481-V484 PolarHBondContact O-N 3.09Å; M481-V484 VanDerWaalsContact O-N 3.16Å; M481-A485 PolarHBondContact O-N 3Å; M481-E510 HydrophobicContact CE-CB 3.89Å; M481-E510 WeakPolarHBondContact CE-O 3.47Å; M481-N514 HydrophobicContact CE-CB 3.86Å; M481-N514 WeakPolarHBondContact CE-ND2 3.42Å; M481-N514 HydrophobicContact SD-CB 4.08Å; M481-F518 HydrophobicContact CB-CE2 3.85Å; M481-F518 HydrophobicContact CB-CZ 4Å; M481-F521 HydrophobicContact SD-CD2 4.46Å; M481-F521 HydrophobicContact SD-CE2 3.37Å; M481-F521 WeakPolarHBondContact SD-CE2 3.39Å; M481-F521 HydrophobicContact SD-CZ 3.7Å
482P98.1Very high97Very high76 Ų7656.4 Ų56.449%0.49428%0.283SS..Hα-helixtrans-58-43.4178.9-26.434.7000113.6N480 V484 A485 E486 F518N480-P482 WeakPolarHBondContact OD1-CD 3.29Å; P482-V484 VanDerWaalsContact C-N 3.34Å; P482-A485 PolarHBondContact O-N 3.38Å; P482-E486 WeakPolarHBondContact O-CB 3.47Å; P482-E486 PolarHBondContact O-N 3.29Å; P482-F518 HydrophobicContact CB-CE1 4.25Å; P482-F518 HydrophobicContact CG-CE1 4.18Å; P482-F518 HydrophobicContact CG-CZ 4.06Å
483A97.9Very high97.1Very high11 Ų1156.1 Ų56.19%0.09128%0.28CS..Hα-helixtrans-69.6-32.917900000112.3I447 N480 M481 Q487I447-A483 HydrophobicContact CB-CB 4.42Å; I447-A483 HydrophobicContact CG1-CB 4.2Å; I447-A483 HydrophobicContact CG2-CB 3.86Å; N480-A483 HydrophobicContact CB-CB 4.18Å; N480-A483 VanDerWaalsContact CG-CB 3.48Å; N480-A483 PolarHBondContact O-N 3.48Å; N480-A483 WeakPolarHBondContact OD1-CB 3.29Å; N480-A483 PolarHBondContact OD1-N 3.4Å; N480-A483 VanDerWaalsContact OD1-N 3.13Å; M481-A483 PolarHBondContact O-N 3.42Å; A483-Q487 VanDerWaalsContact O-CG 3.23Å; A483-Q487 WeakPolarHBondContact O-CG 3.5Å; A483-Q487 PolarHBondContact O-N 3.27Å; A483-Q487 VanDerWaalsContact O-N 3.13Å
484V98.2Very high97.2Very high0 Ų053.1 Ų53.10%027%0.267CS..Hα-helixtrans-62.2-49.5172.3174.10000110.1F443 L446 I447 P477 N480 M481 P482 E486 Q487 L488 L511 F521F443-V484 HydrophobicContact CD1-CG1 4.3Å; F443-V484 HydrophobicContact CD1-CG2 4.08Å; F443-V484 HydrophobicContact CE1-CG1 4.35Å; L446-V484 HydrophobicContact CD2-CG1 3.81Å; I447-V484 HydrophobicContact CD1-CG2 4.14Å; I447-V484 HydrophobicContact CG1-CG2 3.74Å; P477-V484 HydrophobicContact CB-CG2 4.35Å; N480-V484 WeakPolarHBondContact O-CG2 3.07Å; N480-V484 PolarHBondContact O-N 3.28Å; N480-V484 VanDerWaalsContact O-N 3.11Å; M481-V484 WeakPolarHBondContact O-CB 3.41Å; M481-V484 PolarHBondContact O-N 3.09Å; M481-V484 VanDerWaalsContact O-N 3.16Å; P482-V484 VanDerWaalsContact C-N 3.34Å; V484-E486 PolarHBondContact O-N 2.86Å; V484-Q487 PolarHBondContact O-N 3.12Å; V484-L488 HydrophobicContact CG1-CD1 4.21Å; V484-L488 WeakPolarHBondContact O-CG 3.29Å; V484-L488 PolarHBondContact O-N 3.07Å; V484-L511 HydrophobicContact CG1-CD2 4.21Å; V484-F521 HydrophobicContact CG1-CE1 3.94Å; V484-F521 HydrophobicContact CG1-CZ 4.3Å
485A98.1Very high97.3Very high3 Ų347.4 Ų47.43%0.02524%0.242CC..Hα-helixtrans-59.7-46.5177.300000111.9M481 P482 Q487 L488 G489 F518 E520 F521M481-A485 PolarHBondContact O-N 3Å; P482-A485 PolarHBondContact O-N 3.38Å; A485-Q487 VanDerWaalsContact C-N 3.3Å; A485-Q487 PolarHBondContact O-N 2.99Å; A485-L488 PolarHBondContact O-N 3.25Å; A485-G489 PolarHBondContact O-N 2.94Å; A485-F518 HydrophobicContact CB-CB 3.85Å; A485-F518 HydrophobicContact CB-CD1 3.51Å; A485-F518 HydrophobicContact CB-CE1 4.31Å; A485-F518 HydrophobicContact CB-CG 3.84Å; A485-E520 HydrophobicContact CB-CB 4.26Å; A485-E520 WeakPolarHBondContact O-CG 2.92Å; A485-F521 HydrophobicContact CB-CE1 3.78Å; A485-F521 HydrophobicContact CB-CZ 3.87Å
486E98Very high97.5Very high124 Ų12446.4 Ų46.458%0.57924%0.235SC*.Hα-helixtrans-53.8-46.6177.5-174.3-167.8170.900111.7P482 V484 G489 R490P482-E486 WeakPolarHBondContact O-CB 3.47Å; P482-E486 PolarHBondContact O-N 3.29Å; V484-E486 PolarHBondContact O-N 2.86Å; E486-G489 PolarHBondContact O-N 2.94Å; E486-R490 WeakPolarHBondContact O-CB 3.49Å; E486-R490 PolarHBondContact O-N 2.96Å
487Q98.1Very high97.6Very high14 Ų1444.7 Ų44.77%0.06523%0.226CC..Hα-helixtrans-73-39.2-177.2-63-67.2-2100111.9L446 A483 V484 A485 G489 R490 Y491L446-Q487 HydrophobicContact CD1-CB 3.87Å; L446-Q487 HydrophobicContact CG-CB 4.45Å; L446-Q487 VanDerWaalsContact O-CG 3.31Å; L446-Q487 WeakPolarHBondContact O-CG 3.19Å; A483-Q487 VanDerWaalsContact O-CG 3.23Å; A483-Q487 WeakPolarHBondContact O-CG 3.5Å; A483-Q487 PolarHBondContact O-N 3.27Å; A483-Q487 VanDerWaalsContact O-N 3.13Å; V484-Q487 PolarHBondContact O-N 3.12Å; A485-Q487 VanDerWaalsContact C-N 3.3Å; A485-Q487 PolarHBondContact O-N 2.99Å; Q487-G489 VanDerWaalsContact C-N 3.3Å; Q487-G489 PolarHBondContact O-N 3.21Å; Q487-R490 PolarHBondContact O-N 3.38Å; Q487-Y491 WeakPolarHBondContact O-CD2 3.38Å; Q487-Y491 PolarHBondContact O-N 3.29Å; Q487-Y491 VanDerWaalsContact O-N 3.13Å
488L97.9Very high97.7Very high4 Ų444.7 Ų44.72%0.02123%0.226CC..Hα-helixtrans-60.1-42.4172.6-68.2179.1000111.4L446 V484 A485 K492 I493 E520 F521L446-L488 HydrophobicContact CD2-CD2 4.33Å; V484-L488 HydrophobicContact CG1-CD1 4.21Å; V484-L488 WeakPolarHBondContact O-CG 3.29Å; V484-L488 PolarHBondContact O-N 3.07Å; A485-L488 PolarHBondContact O-N 3.25Å; L488-K492 PolarHBondContact O-N 3.47Å; L488-I493 HydrophobicContact CD2-CB 4.05Å; L488-I493 HydrophobicContact CD2-CG1 3.91Å; L488-I493 HydrophobicContact CD2-CG2 4.27Å; L488-I493 PolarHBondContact O-N 3.31Å; L488-E520 HydrophobicContact CB-CB 4.29Å; L488-F521 HydrophobicContact CD1-CD1 3.92Å; L488-F521 HydrophobicContact CD1-CE1 4Å
489G97.1Very high97.8Very high31 Ų3141.5 Ų41.532%0.3220%0.204SC..Hα-helixtrans-64.3-44.3174.900000112.9A485 E486 Q487 Y491 K492A485-G489 PolarHBondContact O-N 2.94Å; E486-G489 PolarHBondContact O-N 2.94Å; Q487-G489 VanDerWaalsContact C-N 3.3Å; Q487-G489 PolarHBondContact O-N 3.21Å; G489-Y491 VanDerWaalsContact C-N 3.33Å; G489-Y491 PolarHBondContact O-N 2.93Å; G489-K492 PolarHBondContact O-N 2.77Å
490R97.3Very high97.9Very high178 Ų17836.8 Ų36.867%0.67218%0.181SC*.Hα-helixtrans-58-42.5179.1-179.4178.3178.6168.60.1112.7E486 Q487 K492E486-R490 WeakPolarHBondContact O-CB 3.49Å; E486-R490 PolarHBondContact O-N 2.96Å; Q487-R490 PolarHBondContact O-N 3.38Å; R490-K492 VanDerWaalsContact C-N 3.31Å
491Y97.1Very high97.9Very high56 Ų5633.6 Ų33.622%0.2216%0.164CC..THydrogen-bonded Turntrans-88.71.7177.7-71.9-94.1000113.1N405 Y437 G449 L451 Q487 G489 I493N405-Y491 PolarHBondContact ND2-O 3.06Å; Y437-Y491 HydrophobicContact CD1-CD1 4.04Å; Y437-Y491 HydrophobicContact CD1-CE1 4.49Å; Y437-Y491 AromaticContact CE1-CD1 3.91Å; Y437-Y491 HydrophobicContact CE1-CD1 3.91Å; Y437-Y491 HydrophobicContact CE1-CE1 4.37Å; G449-Y491 PolarHBondContact O-OH 3.26Å; L451-Y491 HydrophobicContact CB-CD1 4.15Å; L451-Y491 HydrophobicContact CB-CE1 3.81Å; L451-Y491 HydrophobicContact CB-CE2 4.23Å; L451-Y491 HydrophobicContact CB-CG 4.48Å; L451-Y491 HydrophobicContact CD1-CD2 3.94Å; L451-Y491 HydrophobicContact CD1-CE2 3.67Å; L451-Y491 HydrophobicContact CD2-CD1 4.22Å; L451-Y491 HydrophobicContact CD2-CD2 3.91Å; L451-Y491 HydrophobicContact CD2-CE2 4.36Å; L451-Y491 HydrophobicContact CD2-CG 3.84Å; L451-Y491 HydrophobicContact CG-CD2 4.32Å; L451-Y491 HydrophobicContact CG-CE2 4.28Å; Q487-Y491 WeakPolarHBondContact O-CD2 3.38Å; Q487-Y491 PolarHBondContact O-N 3.29Å; Q487-Y491 VanDerWaalsContact O-N 3.13Å; G489-Y491 VanDerWaalsContact C-N 3.33Å; G489-Y491 PolarHBondContact O-N 2.93Å; Y491-I493 VanDerWaalsContact C-N 3.28Å; Y491-I493 PolarHBondContact O-N 2.96Å
492K96.7Very high97.9Very high154 Ų15432.8 Ų32.867%0.6716%0.16SC*.THydrogen-bonded Turntrans51.944-179.1-56.2-176.7177.7-172.90112.4N405 L488 G489 R490 N494N405-K492 WeakPolarHBondContact CB-O 3.38Å; L488-K492 PolarHBondContact O-N 3.47Å; G489-K492 PolarHBondContact O-N 2.77Å; R490-K492 VanDerWaalsContact C-N 3.31Å; K492-N494 PolarHBondContact O-N 2.97Å; K492-N494 PolarHBondContact O-OD1 3.01Å
493I98Very high97.9Very high9 Ų930 Ų305%0.04614%0.14CC..  trans-65.2125.1-177.3-58.4-50.9000109.5N405 A407 Y437 L451 L488 Y491 A495 I523N405-I493 HydrophobicContact CB-CD1 4.36Å; N405-I493 CarbonylContact O-C 3.5Å; A407-I493 HydrophobicContact CB-CD1 3.93Å; A407-I493 HydrophobicContact CB-CG1 4.14Å; A407-I493 HydrophobicContact CB-CG2 3.67Å; Y437-I493 HydrophobicContact CD2-CD1 3.85Å; Y437-I493 HydrophobicContact CG-CD1 4.32Å; L451-I493 HydrophobicContact CD2-CD1 4.48Å; L488-I493 HydrophobicContact CD2-CB 4.05Å; L488-I493 HydrophobicContact CD2-CG1 3.91Å; L488-I493 HydrophobicContact CD2-CG2 4.27Å; L488-I493 PolarHBondContact O-N 3.31Å; Y491-I493 VanDerWaalsContact C-N 3.28Å; Y491-I493 PolarHBondContact O-N 2.96Å; I493-A495 WeakPolarHBondContact CG2-O 3.22Å; I493-I523 HydrophobicContact CG2-CD1 3.98Å
494N97.9Very high97.9Very high20 Ų2029.5 Ų29.511%0.10714%0.136CC..  trans-100-20.8-178.3-62.4120.5000113.4F404 N405 K492 I523 P524 V704F404-N494 WeakPolarHBondContact CA-OD1 3.38Å; F404-N494 HydrophobicContact CB-CB 4.1Å; F404-N494 HydrophobicContact CD1-CB 4.18Å; N405-N494 PolarHBondContact N-OD1 3.41Å; N405-N494 PolarHBondContact O-N 3.21Å; K492-N494 PolarHBondContact O-N 2.97Å; K492-N494 PolarHBondContact O-OD1 3.01Å; N494-I523 WeakPolarHBondContact O-CB 3.39Å; N494-P524 WeakPolarHBondContact O-CD 3.45Å; N494-V704 HydrophobicContact CB-CB 4.14Å; N494-V704 HydrophobicContact CB-CG2 3.86Å
495A98.4Very high97.9Very high0 Ų029.5 Ų29.50%014%0.136CC..EExtended strand (participates in β ladder)trans-156.2151.1171.400000110.5L406 A407 I493 P524 L690L406-A495 WeakPolarHBondContact CA-O 3.28Å; L406-A495 HydrophobicContact CD2-CB 3.78Å; A407-A495 PolarHBondContact N-O 3.05Å; I493-A495 WeakPolarHBondContact CG2-O 3.22Å; A495-P524 VanDerWaalsContact CA-O 3.25Å; A495-P524 WeakPolarHBondContact CA-O 3.1Å; A495-P524 HydrophobicContact CB-CB 4.29Å; A495-L690 HydrophobicContact CB-CB 4.13Å; A495-L690 HydrophobicContact CB-CD1 4.39Å; A495-L690 HydrophobicContact CB-CD2 4.37Å
496L98.6Very high97.9Very high1 Ų131.9 Ų31.91%0.00515%0.147CC..EExtended strand (participates in β ladder)trans-128.4129.6-173.5177.364.8000112.3A407 M409 I439 L498 L511 I523 P524 M525 A526A407-L496 HydrophobicContact CB-CD1 3.77Å; M409-L496 HydrophobicContact CE-CD1 3.7Å; M409-L496 HydrophobicContact CE-CD2 3.94Å; M409-L496 HydrophobicContact CE-CG 4.34Å; I439-L496 HydrophobicContact CD1-CD1 4.04Å; L496-L498 HydrophobicContact CD2-CG 4.47Å; L496-L498 HydrophobicContact CG-CG 4.44Å; L496-L511 HydrophobicContact CD2-CD1 3.95Å; L496-I523 HydrophobicContact CB-CD1 4.29Å; L496-P524 PolarHBondContact N-O 2.72Å; L496-M525 HydrophobicContact CB-CG 4.2Å; L496-M525 HydrophobicContact CD2-SD 4.43Å; L496-M525 CarbonylContact O-C 3.51Å; L496-M525 VanDerWaalsContact O-CA 3.3Å; L496-M525 WeakPolarHBondContact O-CA 3.46Å; L496-A526 PolarHBondContact O-N 2.97Å
497L98.8Very high97.9Very high0 Ų026 Ų260%012%0.119CC..EExtended strand (participates in β ladder)trans-105127168.9176.158.2000111.2A407 V408 M409 F425 V499 A526 I528 V686 L690A407-L497 PolarHBondContact O-N 2.96Å; V408-L497 WeakPolarHBondContact CA-O 3.49Å; V408-L497 HydrophobicContact CB-CB 4.27Å; V408-L497 HydrophobicContact CG2-CB 4.11Å; V408-L497 HydrophobicContact CG2-CD2 3.84Å; V408-L497 HydrophobicContact CG2-CG 3.98Å; M409-L497 PolarHBondContact N-O 3.41Å; F425-L497 HydrophobicContact CB-CD2 3.75Å; F425-L497 HydrophobicContact CD1-CB 4.43Å; F425-L497 HydrophobicContact CD1-CD2 3.93Å; F425-L497 HydrophobicContact CD2-CB 4.32Å; F425-L497 HydrophobicContact CD2-CD2 3.33Å; F425-L497 HydrophobicContact CD2-CG 4.41Å; F425-L497 HydrophobicContact CE1-CB 4.05Å; F425-L497 HydrophobicContact CE1-CD2 4.35Å; F425-L497 HydrophobicContact CE2-CB 3.94Å; F425-L497 HydrophobicContact CE2-CD2 3.82Å; F425-L497 HydrophobicContact CE2-CG 4.47Å; F425-L497 HydrophobicContact CG-CD2 3.38Å; F425-L497 HydrophobicContact CZ-CB 3.78Å; F425-L497 HydrophobicContact CZ-CD2 4.29Å; L497-V499 HydrophobicContact CD1-CG2 4.36Å; L497-V499 HydrophobicContact CD2-CG2 3.95Å; L497-V499 HydrophobicContact CG-CG2 3.92Å; L497-A526 WeakPolarHBondContact CA-O 3.39Å; L497-A526 HydrophobicContact CD1-CB 4.34Å; L497-A526 WeakPolarHBondContact CD1-O 3.48Å; L497-I528 HydrophobicContact CD1-CB 4.47Å; L497-I528 HydrophobicContact CD1-CD1 3.94Å; L497-I528 HydrophobicContact CD1-CG1 3.89Å; L497-I528 HydrophobicContact CD2-CD1 4.11Å; L497-V686 HydrophobicContact CD1-CG1 3.72Å; L497-L690 HydrophobicContact CB-CD1 4.31Å
498L98.7Very high97.9Very high0 Ų025.3 Ų25.30%012%0.116CC..EExtended strand (participates in β ladder)trans-107.9117.1171-64.2150.1000108.8M409 V411 F443 L496 A504 C508 A526 V527 I528M409-L498 HydrophobicContact CE-CD2 3.87Å; M409-L498 HydrophobicContact CG-CD2 3.74Å; M409-L498 HydrophobicContact SD-CD2 3.87Å; V411-L498 HydrophobicContact CG2-CD2 3.76Å; F443-L498 HydrophobicContact CE2-CD2 4.07Å; F443-L498 HydrophobicContact CZ-CD2 3.82Å; L496-L498 HydrophobicContact CD2-CG 4.47Å; L496-L498 HydrophobicContact CG-CG 4.44Å; L498-A504 HydrophobicContact CB-CB 4.27Å; L498-C508 HydrophobicContact CD1-CB 3.68Å; L498-A526 PolarHBondContact N-O 3.39Å; L498-V527 HydrophobicContact CB-CG2 4.25Å; L498-V527 HydrophobicContact CD1-CG2 4.17Å; L498-V527 CarbonylContact O-C 3.58Å; L498-V527 VanDerWaalsContact O-CA 3.29Å; L498-V527 WeakPolarHBondContact O-CA 3.45Å; L498-I528 PolarHBondContact O-N 3.28Å
499V98.7Very high97.9Very high0 Ų025.2 Ų25.20%012%0.115CC..EExtended strand (participates in β ladder)trans-105.7119.8174.5-176.40000108.7V408 M409 N410 V411 M418 A421 L497 I528 C530V408-V499 HydrophobicContact CG2-CG2 4.25Å; M409-V499 PolarHBondContact O-N 2.76Å; N410-V499 CarbonylContact C-O 3.52Å; N410-V499 WeakPolarHBondContact CA-O 3.4Å; N410-V499 WeakPolarHBondContact OD1-CB 3.17Å; V411-V499 PolarHBondContact N-O 3.38Å; M418-V499 HydrophobicContact CG-CG1 4.31Å; A421-V499 HydrophobicContact CB-CG1 4.08Å; A421-V499 HydrophobicContact CB-CG2 4.26Å; L497-V499 HydrophobicContact CD1-CG2 4.36Å; L497-V499 HydrophobicContact CD2-CG2 3.95Å; L497-V499 HydrophobicContact CG-CG2 3.92Å; V499-I528 HydrophobicContact CG1-CG2 4.44Å; V499-I528 HydrophobicContact CG2-CB 4.41Å; V499-C530 HydrophobicContact CG1-CB 3.75Å
500G98.1Very high98Very high0 Ų024.9 Ų24.90%011%0.106CC..EExtended strand (participates in β ladder)trans163.9-170.5-177.800000117V411 I528 P529 C530V411-G500 WeakPolarHBondContact O-CA 3.33Å; G500-I528 PolarHBondContact N-O 3.29Å; G500-P529 CarbonylContact O-C 3.5Å; G500-P529 WeakPolarHBondContact O-CA 3.22Å; G500-C530 CarbonylContact C-O 3.6Å; G500-C530 WeakPolarHBondContact CA-O 3.24Å; G500-C530 PolarHBondContact O-N 2.95Å
501G97.1Very high98Very high2 Ų216.5 Ų16.52%0.0217%0.074CC..SBendtrans-84-150.3-176.600000113.2V411 E503 A504 Y505 C530V411-G501 PolarHBondContact O-N 3.22Å; G501-E503 PolarHBondContact O-N 3.45Å; G501-A504 WeakPolarHBondContact O-CB 3.33Å; G501-A504 PolarHBondContact O-N 2.97Å; G501-Y505 PolarHBondContact O-N 3.45Å; G501-C530 PolarHBondContact N-O 3.26Å; G501-C530 VanDerWaalsContact N-O 3.15Å
502F97.7Very high98.1Very high6 Ų614.2 Ų14.23%0.0267%0.066CC..Hα-helixtrans-58-33.7179.8-162.5-85.6000112.8A504 Y505 H506 P537 T734 F736 R739F502-A504 VanDerWaalsContact C-N 3.34Å; F502-A504 PolarHBondContact O-N 3.07Å; F502-Y505 HydrophobicContact CD2-CD1 4.38Å; F502-Y505 HydrophobicContact CE2-CD1 4.29Å; F502-Y505 HydrophobicContact CE2-CE1 4.37Å; F502-Y505 HydrophobicContact CZ-CD1 4.44Å; F502-Y505 HydrophobicContact CZ-CE1 4.41Å; F502-Y505 PolarHBondContact O-N 3.43Å; F502-H506 HydrophobicContact CD1-CB 4.48Å; F502-H506 WeakPolarHBondContact O-CB 3.36Å; F502-H506 PolarHBondContact O-N 2.57Å; F502-P537 HydrophobicContact CE2-CG 4.32Å; F502-T734 HydrophobicContact CE2-CG2 3.6Å; F502-T734 HydrophobicContact CZ-CG2 3.43Å; F502-T734 VanDerWaalsContact CZ-CG2 3.43Å; F502-F736 AromaticContact CE1-CD1 3.83Å; F502-F736 HydrophobicContact CE1-CD1 3.83Å; F502-F736 HydrophobicContact CE1-CE1 4.14Å; F502-F736 AromaticContact CZ-CD1 3.84Å; F502-F736 HydrophobicContact CZ-CD1 3.84Å; F502-F736 HydrophobicContact CZ-CE1 4.11Å; F502-F736 HydrophobicContact CZ-CG 4.37Å; F502-R739 HydrophobicContact CB-CB 4.49Å; F502-R739 HydrophobicContact CD1-CB 3.96Å; F502-R739 HydrophobicContact CD1-CG 3.84Å; F502-R739 HydrophobicContact CD2-CB 3.8Å; F502-R739 HydrophobicContact CE1-CB 4.06Å; F502-R739 HydrophobicContact CE1-CG 3.84Å; F502-R739 HydrophobicContact CE2-CB 3.89Å; F502-R739 HydrophobicContact CG-CB 3.83Å; F502-R739 HydrophobicContact CG-CG 4.21Å; F502-R739 HydrophobicContact CZ-CB 4.02Å; F502-R739 HydrophobicContact CZ-CG 4.21Å
503E97.9Very high98.1Very high17 Ų1710.8 Ų10.88%0.0795%0.052CC..Hα-helixtrans-64.4-35.2175.1-69.383.8175.300112.8V411 K474 L476 G501 A507 R739V411-E503 HydrophobicContact CG1-CB 3.93Å; K474-E503 HydrophobicContact CB-CG 4.07Å; K474-E503 HydrophobicContact CG-CG 4.35Å; L476-E503 HydrophobicContact CD2-CB 4.28Å; L476-E503 WeakPolarHBondContact CD2-O 3.4Å; G501-E503 PolarHBondContact O-N 3.45Å; E503-A507 WeakPolarHBondContact O-CB 3.37Å; E503-A507 PolarHBondContact O-N 3.15Å; E503-R739 IonicContact OE1-CZ 3.07Å; E503-R739 IonicContact OE1-NH1 2.85Å; E503-R739 PolarHBondContact OE1-NH1 3.02Å; E503-R739 IonicContact OE1-NH2 3.75Å; E503-R739 PolarHBondContact OE1-NH2 3.49Å; E503-R739 IonicContact OE2-CZ 2.77Å; E503-R739 IonicContact OE2-NH2 2.58Å; E503-R739 PolarHBondContact OE2-NH2 3.21Å
504A98.2Very high98Very high0 Ų012 Ų120%06%0.059CC..Hα-helixtrans-66.5-43.7176.200000111V411 L498 G501 F502 C508 V527V411-A504 HydrophobicContact CB-CB 3.92Å; L498-A504 HydrophobicContact CB-CB 4.27Å; G501-A504 WeakPolarHBondContact O-CB 3.33Å; G501-A504 PolarHBondContact O-N 2.97Å; F502-A504 VanDerWaalsContact C-N 3.34Å; F502-A504 PolarHBondContact O-N 3.07Å; A504-C508 PolarHBondContact O-N 2.9Å; A504-C508 VanDerWaalsContact O-N 3.07Å; A504-V527 HydrophobicContact CB-CG1 4.15Å
505Y98.2Very high98Very high0 Ų011.6 Ų11.60%06%0.056CC..Hα-helixtrans-61.1-49.7174163.7-116.4000111.9G501 F502 A507 C508 I509 V536 P537 L714 V727 L730 K731 T734 F736G501-Y505 PolarHBondContact O-N 3.45Å; F502-Y505 HydrophobicContact CD2-CD1 4.38Å; F502-Y505 HydrophobicContact CE2-CD1 4.29Å; F502-Y505 HydrophobicContact CE2-CE1 4.37Å; F502-Y505 HydrophobicContact CZ-CD1 4.44Å; F502-Y505 HydrophobicContact CZ-CE1 4.41Å; F502-Y505 PolarHBondContact O-N 3.43Å; Y505-A507 PolarHBondContact O-N 3.28Å; Y505-C508 WeakPolarHBondContact O-CB 3.35Å; Y505-C508 PolarHBondContact O-N 3.42Å; Y505-I509 HydrophobicContact CD1-CD1 4.46Å; Y505-I509 HydrophobicContact CD2-CD1 4.24Å; Y505-I509 HydrophobicContact CE1-CD1 3.87Å; Y505-I509 HydrophobicContact CE2-CD1 3.59Å; Y505-I509 HydrophobicContact CE2-CG1 4.17Å; Y505-I509 PolarHBondContact O-N 3.27Å; Y505-I509 VanDerWaalsContact O-N 3.13Å; Y505-V536 HydrophobicContact CG-CG1 4.49Å; Y505-P537 HydrophobicContact CD1-CG 4.42Å; Y505-P537 HydrophobicContact CE1-CB 4.47Å; Y505-P537 HydrophobicContact CE1-CG 3.85Å; Y505-L714 HydrophobicContact CD2-CD1 3.8Å; Y505-L714 HydrophobicContact CG-CD1 4.31Å; Y505-V727 HydrophobicContact CD2-CB 4.38Å; Y505-V727 HydrophobicContact CD2-CG1 4.28Å; Y505-V727 HydrophobicContact CE2-CB 4.11Å; Y505-V727 HydrophobicContact CE2-CG1 4.42Å; Y505-L730 HydrophobicContact CE2-CB 3.87Å; Y505-L730 HydrophobicContact CE2-CD1 4.23Å; Y505-L730 VanDerWaalsContact OH-CB 3.31Å; Y505-L730 WeakPolarHBondContact OH-CB 3.23Å; Y505-L730 PolarHBondContact OH-O 3.24Å; Y505-K731 WeakPolarHBondContact OH-CA 3.24Å; Y505-K731 PolarHBondContact OH-N 2.95Å; Y505-T734 HydrophobicContact CE1-CG2 4.01Å; Y505-T734 PolarHBondContact OH-OG1 3.21Å; Y505-F736 HydrophobicContact CE1-CE1 4.48Å; Y505-F736 HydrophobicContact CE1-CZ 4.3Å
506H98Very high98Very high54 Ų5418.6 Ų18.625%0.259%0.088CC..Hα-helixtrans-63.7-40.6179.1-171.4-162.8000112L476 F502 C508 I509 E510 F736L476-H506 HydrophobicContact CD2-CB 4.26Å; F502-H506 HydrophobicContact CD1-CB 4.48Å; F502-H506 WeakPolarHBondContact O-CB 3.36Å; F502-H506 PolarHBondContact O-N 2.57Å; H506-C508 VanDerWaalsContact C-N 3.3Å; H506-C508 PolarHBondContact O-N 3.03Å; H506-I509 WeakPolarHBondContact O-CB 3.49Å; H506-I509 PolarHBondContact O-N 2.89Å; H506-E510 IonicContact CE1-OE1 3.14Å; H506-E510 PolarHBondContact O-N 3.28Å; H506-F736 AromaticContact CD2-CE1 3.95Å
507A98.2Very high97.9Very high0 Ų024.1 Ų24.10%011%0.114CC..Hα-helixtrans-61-39.3174.700000112.5F443 L476 P477 E503 Y505 I509 E510 L511F443-A507 HydrophobicContact CD2-CB 4.48Å; F443-A507 HydrophobicContact CE2-CB 3.42Å; F443-A507 VanDerWaalsContact CE2-CB 3.42Å; F443-A507 HydrophobicContact CZ-CB 3.68Å; L476-A507 HydrophobicContact CD2-CB 4.07Å; P477-A507 HydrophobicContact CG-CB 4.08Å; E503-A507 WeakPolarHBondContact O-CB 3.37Å; E503-A507 PolarHBondContact O-N 3.15Å; Y505-A507 PolarHBondContact O-N 3.28Å; A507-I509 VanDerWaalsContact C-N 3.34Å; A507-E510 PolarHBondContact O-N 3.34Å; A507-L511 VanDerWaalsContact O-CG 3.31Å; A507-L511 WeakPolarHBondContact O-CG 3.35Å; A507-L511 PolarHBondContact O-N 2.57Å
508C98.3Very high97.8Very high0 Ų025.9 Ų25.90%012%0.122CC..Hα-helixtrans-62.1-43.6175.4-163.50000111.1L498 A504 Y505 H506 L511 T512 V527 V727L498-C508 HydrophobicContact CD1-CB 3.68Å; A504-C508 PolarHBondContact O-N 2.9Å; A504-C508 VanDerWaalsContact O-N 3.07Å; Y505-C508 WeakPolarHBondContact O-CB 3.35Å; Y505-C508 PolarHBondContact O-N 3.42Å; H506-C508 VanDerWaalsContact C-N 3.3Å; H506-C508 PolarHBondContact O-N 3.03Å; C508-L511 PolarHBondContact O-N 2.92Å; C508-T512 PolarHBondContact O-N 2.83Å; C508-T512 PolarHBondContact O-OG1 3.25Å; C508-V527 HydrophobicContact CB-CG2 3.43Å; C508-V527 VanDerWaalsContact CB-CG2 3.43Å; C508-V727 HydrophobicContact CB-CG1 4.17Å
509I98.1Very high97.7Very high1 Ų133 Ų331%0.00515%0.152CC..Hα-helixtrans-57.6-51.8173.8-69.1173.4000110.8Y505 H506 A507 L511 T512 E513 V727 L728 K731 F736Y505-I509 HydrophobicContact CD1-CD1 4.46Å; Y505-I509 HydrophobicContact CD2-CD1 4.24Å; Y505-I509 HydrophobicContact CE1-CD1 3.87Å; Y505-I509 HydrophobicContact CE2-CD1 3.59Å; Y505-I509 HydrophobicContact CE2-CG1 4.17Å; Y505-I509 PolarHBondContact O-N 3.27Å; Y505-I509 VanDerWaalsContact O-N 3.13Å; H506-I509 WeakPolarHBondContact O-CB 3.49Å; H506-I509 PolarHBondContact O-N 2.89Å; A507-I509 VanDerWaalsContact C-N 3.34Å; I509-L511 VanDerWaalsContact C-N 3.3Å; I509-L511 PolarHBondContact O-N 3.48Å; I509-T512 PolarHBondContact O-N 3.41Å; I509-T512 VanDerWaalsContact O-N 3.12Å; I509-E513 HydrophobicContact CG2-CG 4.16Å; I509-E513 WeakPolarHBondContact O-CG 3.38Å; I509-E513 PolarHBondContact O-N 3.41Å; I509-V727 HydrophobicContact CG1-CB 3.91Å; I509-V727 HydrophobicContact CG1-CG2 3.97Å; I509-L728 HydrophobicContact CG1-CD2 4.42Å; I509-L728 HydrophobicContact CG2-CD2 3.99Å; I509-K731 HydrophobicContact CD1-CB 4.08Å; I509-K731 HydrophobicContact CD1-CG 4.29Å; I509-K731 HydrophobicContact CG2-CD 4.03Å; I509-F736 HydrophobicContact CD1-CE1 4.35Å; I509-F736 HydrophobicContact CD1-CZ 3.86Å
510E97.9Very high97.7Very high25 Ų2535.5 Ų35.512%0.11716%0.164CC..Hα-helixtrans-56.2-45.5-179.1-75.7-170.7174.400111.4P477 S478 M481 H506 A507 N514P477-E510 WeakPolarHBondContact CD-OE2 3.33Å; P477-E510 HydrophobicContact CG-CB 3.91Å; P477-E510 VanDerWaalsContact CG-OE2 3.26Å; P477-E510 WeakPolarHBondContact CG-OE2 3.49Å; S478-E510 WeakPolarHBondContact CB-OE1 3.2Å; S478-E510 WeakPolarHBondContact CB-OE2 3.21Å; S478-E510 PolarHBondContact N-OE2 3.12Å; S478-E510 VanDerWaalsContact OG-CD 3.32Å; S478-E510 PolarHBondContact OG-OE1 3Å; S478-E510 PolarHBondContact OG-OE2 3.48Å; M481-E510 HydrophobicContact CE-CB 3.89Å; M481-E510 WeakPolarHBondContact CE-O 3.47Å; H506-E510 IonicContact CE1-OE1 3.14Å; H506-E510 PolarHBondContact O-N 3.28Å; A507-E510 PolarHBondContact O-N 3.34Å; E510-N514 WeakPolarHBondContact O-CB 3.35Å; E510-N514 PolarHBondContact O-N 2.74Å; E510-N514 PolarHBondContact O-ND2 2.74Å
511L98.2Very high97.7Very high1 Ų135.6 Ų35.61%0.00517%0.165CC..Hα-helixtrans-62-45177.1-67.4171.4000111.7F443 P477 V484 L496 A507 C508 I509 N514 R515 F521 M525F443-L511 HydrophobicContact CE1-CD1 4.23Å; F443-L511 HydrophobicContact CZ-CD1 4.19Å; P477-L511 HydrophobicContact CB-CD2 3.83Å; P477-L511 HydrophobicContact CB-CG 4.32Å; P477-L511 HydrophobicContact CG-CD2 4.03Å; P477-L511 HydrophobicContact CG-CG 3.96Å; V484-L511 HydrophobicContact CG1-CD2 4.21Å; L496-L511 HydrophobicContact CD2-CD1 3.95Å; A507-L511 VanDerWaalsContact O-CG 3.31Å; A507-L511 WeakPolarHBondContact O-CG 3.35Å; A507-L511 PolarHBondContact O-N 2.57Å; C508-L511 PolarHBondContact O-N 2.92Å; I509-L511 VanDerWaalsContact C-N 3.3Å; I509-L511 PolarHBondContact O-N 3.48Å; L511-N514 PolarHBondContact O-N 3Å; L511-R515 PolarHBondContact O-N 2.91Å; L511-F521 HydrophobicContact CD2-CD1 3.83Å; L511-F521 HydrophobicContact CD2-CD2 4.19Å; L511-F521 HydrophobicContact CD2-CE1 3.69Å; L511-F521 HydrophobicContact CD2-CE2 4.05Å; L511-F521 HydrophobicContact CD2-CG 4.1Å; L511-F521 HydrophobicContact CD2-CZ 3.81Å; L511-M525 HydrophobicContact CB-CE 3.86Å; L511-M525 HydrophobicContact CB-SD 3.77Å; L511-M525 HydrophobicContact CD1-SD 3.8Å; L511-M525 HydrophobicContact CG-SD 4.43Å
512T97.9Very high97.7Very high9 Ų935.5 Ų35.56%0.05516%0.164CC..Hα-helixtrans-63.9-44.1179.9-57.90000112C508 I509 N514 R515 M525 A712 L728C508-T512 PolarHBondContact O-N 2.83Å; C508-T512 PolarHBondContact O-OG1 3.25Å; I509-T512 PolarHBondContact O-N 3.41Å; I509-T512 VanDerWaalsContact O-N 3.12Å; T512-N514 PolarHBondContact O-N 2.7Å; T512-R515 WeakPolarHBondContact O-CB 3.31Å; T512-R515 WeakPolarHBondContact O-CG 3.4Å; T512-R515 PolarHBondContact O-N 2.79Å; T512-M525 WeakPolarHBondContact OG1-CE 3.41Å; T512-A712 HydrophobicContact CG2-CB 3.94Å; T512-A712 WeakPolarHBondContact OG1-CB 3.21Å; T512-L728 HydrophobicContact CG2-CD1 3.87Å; T512-L728 HydrophobicContact CG2-CG 4.1Å
513E97Very high97.7Very high81 Ų8135.5 Ų35.538%0.37916%0.164SC..Hα-helixtrans-66.2-26.5179.7-67.8-171.4138.600112.2I509 H516 L728 K731I509-E513 HydrophobicContact CG2-CG 4.16Å; I509-E513 WeakPolarHBondContact O-CG 3.38Å; I509-E513 PolarHBondContact O-N 3.41Å; E513-H516 PolarHBondContact O-CE1 3.32Å; E513-H516 PolarHBondContact O-ND1 3.35Å; E513-L728 HydrophobicContact CG-CD2 3.84Å; E513-K731 IonicContact OE1-NZ 3.15Å; E513-K731 PolarHBondContact OE1-NZ 2.96Å; E513-K731 IonicContact OE2-NZ 3.05Å; E513-K731 PolarHBondContact OE2-NZ 3.48Å
514N97.3Very high97.8Very high34 Ų3434.7 Ų34.718%0.18216%0.16CC..THydrogen-bonded Turntrans-95.59.5-179.7-72.4-87.9000114.4M481 E510 L511 T512 H516 Q517 F518 F521M481-N514 HydrophobicContact CE-CB 3.86Å; M481-N514 WeakPolarHBondContact CE-ND2 3.42Å; M481-N514 HydrophobicContact SD-CB 4.08Å; E510-N514 WeakPolarHBondContact O-CB 3.35Å; E510-N514 PolarHBondContact O-N 2.74Å; E510-N514 PolarHBondContact O-ND2 2.74Å; L511-N514 PolarHBondContact O-N 3Å; T512-N514 PolarHBondContact O-N 2.7Å; N514-H516 PolarHBondContact O-N 3Å; N514-Q517 PolarHBondContact O-N 2.84Å; N514-F518 HydrophobicContact CB-CD2 4.34Å; N514-F518 PolarHBondContact O-N 3.29Å; N514-F521 HydrophobicContact CB-CD2 4.03Å; N514-F521 HydrophobicContact CB-CE2 4.05Å
515R97.8Very high97.8Very high12 Ų1234.8 Ų34.85%0.04516%0.161CC..THydrogen-bonded Turntrans-54.6-33.9174.5-79.9176.9169-176.4-1.6114L511 T512 Q517 F521 C522 I523 D707 N708 T711L511-R515 PolarHBondContact O-N 2.91Å; T512-R515 WeakPolarHBondContact O-CB 3.31Å; T512-R515 WeakPolarHBondContact O-CG 3.4Å; T512-R515 PolarHBondContact O-N 2.79Å; R515-Q517 PolarHBondContact O-N 3.16Å; R515-F521 HydrophobicContact CG-CB 3.94Å; R515-F521 WeakPolarHBondContact CG-O 3.28Å; R515-F521 PolarHBondContact NE-O 2.84Å; R515-C522 PolarHBondContact O-SG 2.83Å; R515-I523 PolarHBondContact NH2-O 2.96Å; R515-D707 PolarHBondContact NH1-O 2.91Å; R515-D707 VanDerWaalsContact NH1-O 3.13Å; R515-N708 VanDerWaalsContact NH1-C 3.33Å; R515-N708 PolarHBondContact NH1-O 3.36Å; R515-T711 PolarHBondContact NH1-OG1 3.03Å; R515-T711 VanDerWaalsContact NH1-OG1 3.17Å; R515-T711 PolarHBondContact NH2-OG1 3.14Å
516H96.6Very high97.8Very high147 Ų14734.8 Ų34.868%0.68116%0.161SC*.THydrogen-bonded Turntrans-67.3-21.7177.666.9-80.4000113.7E513 N514E513-H516 PolarHBondContact O-CE1 3.32Å; E513-H516 PolarHBondContact O-ND1 3.35Å; N514-H516 PolarHBondContact O-N 3Å
517Q96.9Very high97.8Very high117 Ų11732.2 Ų32.255%0.54715%0.149SC..THydrogen-bonded Turntrans-96.5-34.7-179.8-57.2-174.215.200112.2N514 R515N514-Q517 PolarHBondContact O-N 2.84Å; R515-Q517 PolarHBondContact O-N 3.16Å
518F97.6Very high97.8Very high37 Ų3732.2 Ų32.216%0.16215%0.149CC..  trans-129.1109.6-174.8-53.8-82.8000110M481 P482 A485 N514 E520 F521M481-F518 HydrophobicContact CB-CE2 3.85Å; M481-F518 HydrophobicContact CB-CZ 4Å; P482-F518 HydrophobicContact CB-CE1 4.25Å; P482-F518 HydrophobicContact CG-CE1 4.18Å; P482-F518 HydrophobicContact CG-CZ 4.06Å; A485-F518 HydrophobicContact CB-CB 3.85Å; A485-F518 HydrophobicContact CB-CD1 3.51Å; A485-F518 HydrophobicContact CB-CE1 4.31Å; A485-F518 HydrophobicContact CB-CG 3.84Å; N514-F518 HydrophobicContact CB-CD2 4.34Å; N514-F518 PolarHBondContact O-N 3.29Å; F518-E520 PolarHBondContact O-N 3.4Å; F518-E520 VanDerWaalsContact O-N 3.14Å; F518-F521 HydrophobicContact CB-CD1 4.42Å; F518-F521 HydrophobicContact CB-CD2 3.68Å; F518-F521 HydrophobicContact CB-CE1 4.39Å; F518-F521 HydrophobicContact CB-CE2 3.65Å; F518-F521 HydrophobicContact CB-CG 4.06Å; F518-F521 HydrophobicContact CB-CZ 4.02Å; F518-F521 AromaticContact CD2-CD2 3.93Å; F518-F521 HydrophobicContact CD2-CD2 3.93Å; F518-F521 AromaticContact CD2-CE2 3.3Å; F518-F521 HydrophobicContact CD2-CE2 3.3Å; F518-F521 AromaticContact CD2-CZ 3.97Å; F518-F521 HydrophobicContact CD2-CZ 3.97Å; F518-F521 HydrophobicContact CE2-CE2 4.16Å; F518-F521 HydrophobicContact CG-CD2 4.19Å; F518-F521 AromaticContact CG-CE2 3.69Å; F518-F521 HydrophobicContact CG-CE2 3.69Å; F518-F521 HydrophobicContact CG-CZ 4.03Å; F518-F521 PolarHBondContact O-N 2.86Å
519K96.5Very high97.8Very high149 Ų14932.2 Ų32.265%0.64815%0.149SC*.G310 helixtrans-60.1-24.8178.166.9176.7-176.51790112.5F521 C522 Y705K519-F521 PolarHBondContact O-N 2.59Å; K519-C522 VanDerWaalsContact O-CB 3.24Å; K519-C522 WeakPolarHBondContact O-CB 3.42Å; K519-C522 PolarHBondContact O-N 2.84Å; K519-Y705 HydrophobicContact CB-CE2 4.41Å
520E97.6Very high97.8Very high54 Ų5432.2 Ų32.225%0.25215%0.149SC..G310 helixtrans-68-15.8178.4-65.974.9-162.300112.8A485 L488 F518A485-E520 HydrophobicContact CB-CB 4.26Å; A485-E520 WeakPolarHBondContact O-CG 2.92Å; L488-E520 HydrophobicContact CB-CB 4.29Å; F518-E520 PolarHBondContact O-N 3.4Å; F518-E520 VanDerWaalsContact O-N 3.14Å
521F98.1Very high97.8Very high1 Ų131.6 Ų31.60%0.00415%0.147CC..G310 helixtrans-89.3-9.1171.9-54.9-19.6000112.7M481 V484 A485 L488 L511 N514 R515 F518 K519 I523M481-F521 HydrophobicContact SD-CD2 4.46Å; M481-F521 HydrophobicContact SD-CE2 3.37Å; M481-F521 WeakPolarHBondContact SD-CE2 3.39Å; M481-F521 HydrophobicContact SD-CZ 3.7Å; V484-F521 HydrophobicContact CG1-CE1 3.94Å; V484-F521 HydrophobicContact CG1-CZ 4.3Å; A485-F521 HydrophobicContact CB-CE1 3.78Å; A485-F521 HydrophobicContact CB-CZ 3.87Å; L488-F521 HydrophobicContact CD1-CD1 3.92Å; L488-F521 HydrophobicContact CD1-CE1 4Å; L511-F521 HydrophobicContact CD2-CD1 3.83Å; L511-F521 HydrophobicContact CD2-CD2 4.19Å; L511-F521 HydrophobicContact CD2-CE1 3.69Å; L511-F521 HydrophobicContact CD2-CE2 4.05Å; L511-F521 HydrophobicContact CD2-CG 4.1Å; L511-F521 HydrophobicContact CD2-CZ 3.81Å; N514-F521 HydrophobicContact CB-CD2 4.03Å; N514-F521 HydrophobicContact CB-CE2 4.05Å; R515-F521 HydrophobicContact CG-CB 3.94Å; R515-F521 WeakPolarHBondContact CG-O 3.28Å; R515-F521 PolarHBondContact NE-O 2.84Å; F518-F521 HydrophobicContact CB-CD1 4.42Å; F518-F521 HydrophobicContact CB-CD2 3.68Å; F518-F521 HydrophobicContact CB-CE1 4.39Å; F518-F521 HydrophobicContact CB-CE2 3.65Å; F518-F521 HydrophobicContact CB-CG 4.06Å; F518-F521 HydrophobicContact CB-CZ 4.02Å; F518-F521 AromaticContact CD2-CD2 3.93Å; F518-F521 HydrophobicContact CD2-CD2 3.93Å; F518-F521 AromaticContact CD2-CE2 3.3Å; F518-F521 HydrophobicContact CD2-CE2 3.3Å; F518-F521 AromaticContact CD2-CZ 3.97Å; F518-F521 HydrophobicContact CD2-CZ 3.97Å; F518-F521 HydrophobicContact CE2-CE2 4.16Å; F518-F521 HydrophobicContact CG-CD2 4.19Å; F518-F521 AromaticContact CG-CE2 3.69Å; F518-F521 HydrophobicContact CG-CE2 3.69Å; F518-F521 HydrophobicContact CG-CZ 4.03Å; F518-F521 PolarHBondContact O-N 2.86Å; K519-F521 PolarHBondContact O-N 2.59Å; F521-I523 PolarHBondContact O-N 2.93Å
522C98.1Very high97.8Very high0 Ų032 Ų320%015%0.149CC..  trans-77.652.9177-60.20000111.3R515 K519 Y705 T706R515-C522 PolarHBondContact O-SG 2.83Å; K519-C522 VanDerWaalsContact O-CB 3.24Å; K519-C522 WeakPolarHBondContact O-CB 3.42Å; K519-C522 PolarHBondContact O-N 2.84Å; C522-Y705 HydrophobicContact CB-CD2 3.63Å; C522-Y705 HydrophobicContact CB-CE2 3.48Å; C522-Y705 VanDerWaalsContact CB-CE2 3.48Å; C522-Y705 HydrophobicContact CB-CG 4.32Å; C522-Y705 CarbonylContact O-C 3.39Å; C522-Y705 WeakPolarHBondContact O-CA 3.13Å; C522-T706 CarbonylContact C-O 3.43Å; C522-T706 WeakPolarHBondContact CA-O 3.32Å; C522-T706 WeakPolarHBondContact CB-O 3.36Å; C522-T706 PolarHBondContact O-N 3.06Å
523I98Very high97.8Very high6 Ų632.5 Ų32.53%0.03115%0.153CC..SBendtrans-128.5157177.457.4172.3000109.8I493 N494 L496 R515 F521 M525I493-I523 HydrophobicContact CG2-CD1 3.98Å; N494-I523 WeakPolarHBondContact O-CB 3.39Å; L496-I523 HydrophobicContact CB-CD1 4.29Å; R515-I523 PolarHBondContact NH2-O 2.96Å; F521-I523 PolarHBondContact O-N 2.93Å; I523-M525 HydrophobicContact CG1-CG 4.34Å; I523-M525 PolarHBondContact O-N 3.25Å
524P98.5Very high97.8Very high0 Ų028.9 Ų28.90%014%0.136CC..  trans-58.2133.7169.4-25.135.4000111.9N494 A495 L496 L690 M693 V704 T706 T711N494-P524 WeakPolarHBondContact O-CD 3.45Å; A495-P524 VanDerWaalsContact CA-O 3.25Å; A495-P524 WeakPolarHBondContact CA-O 3.1Å; A495-P524 HydrophobicContact CB-CB 4.29Å; L496-P524 PolarHBondContact N-O 2.72Å; P524-L690 HydrophobicContact CB-CD2 3.82Å; P524-M693 HydrophobicContact CB-CB 4Å; P524-M693 HydrophobicContact CB-SD 4.46Å; P524-M693 HydrophobicContact CG-CB 3.84Å; P524-V704 HydrophobicContact CG-CG1 4.37Å; P524-T706 HydrophobicContact CG-CG2 4.14Å; P524-T711 WeakPolarHBondContact CA-O 3.33Å
525M98.7Very high97.8Very high2 Ų227.8 Ų27.81%0.0113%0.13CC..EExtended strand (participates in β ladder)trans-132.1143179.3-61.6-174.4-77.500110.1L496 L511 T512 I523 T711 A712 L713L496-M525 HydrophobicContact CB-CG 4.2Å; L496-M525 HydrophobicContact CD2-SD 4.43Å; L496-M525 CarbonylContact O-C 3.51Å; L496-M525 VanDerWaalsContact O-CA 3.3Å; L496-M525 WeakPolarHBondContact O-CA 3.46Å; L511-M525 HydrophobicContact CB-CE 3.86Å; L511-M525 HydrophobicContact CB-SD 3.77Å; L511-M525 HydrophobicContact CD1-SD 3.8Å; L511-M525 HydrophobicContact CG-SD 4.43Å; T512-M525 WeakPolarHBondContact OG1-CE 3.41Å; I523-M525 HydrophobicContact CG1-CG 4.34Å; I523-M525 PolarHBondContact O-N 3.25Å; M525-T711 PolarHBondContact N-O 3.01Å; M525-T711 VanDerWaalsContact O-O 3.1Å; M525-A712 HydrophobicContact CB-CB 4.43Å; M525-A712 HydrophobicContact CE-CB 4.12Å; M525-A712 CarbonylContact O-C 3.16Å; M525-A712 WeakPolarHBondContact O-CA 3.5Å; M525-L713 PolarHBondContact O-N 3.01Å
526A98.5Very high97.7Very high1 Ų127.2 Ų27.21%0.00813%0.128CC..EExtended strand (participates in β ladder)trans-137.2145.7175.200000112.2L496 L497 L498 V686 L690 L713L496-A526 PolarHBondContact O-N 2.97Å; L497-A526 WeakPolarHBondContact CA-O 3.39Å; L497-A526 HydrophobicContact CD1-CB 4.34Å; L497-A526 WeakPolarHBondContact CD1-O 3.48Å; L498-A526 PolarHBondContact N-O 3.39Å; A526-V686 HydrophobicContact CB-CG1 3.4Å; A526-V686 VanDerWaalsContact CB-CG1 3.4Å; A526-V686 HydrophobicContact CB-CG2 4.49Å; A526-L690 HydrophobicContact CB-CD1 4.05Å; A526-L690 HydrophobicContact CB-CD2 3.89Å; A526-L690 HydrophobicContact CB-CG 4.08Å; A526-L713 CarbonylContact C-O 3.53Å; A526-L713 VanDerWaalsContact CA-O 3.22Å; A526-L713 WeakPolarHBondContact CA-O 3.36Å
527V98.6Very high97.7Very high0 Ų020.3 Ų20.30%010%0.096CC..EExtended strand (participates in β ladder)trans-111.8130.5173.7-176.30000109.7L498 A504 C508 L713 L714 L715 V727L498-V527 HydrophobicContact CB-CG2 4.25Å; L498-V527 HydrophobicContact CD1-CG2 4.17Å; L498-V527 CarbonylContact O-C 3.58Å; L498-V527 VanDerWaalsContact O-CA 3.29Å; L498-V527 WeakPolarHBondContact O-CA 3.45Å; A504-V527 HydrophobicContact CB-CG1 4.15Å; C508-V527 HydrophobicContact CB-CG2 3.43Å; C508-V527 VanDerWaalsContact CB-CG2 3.43Å; V527-L713 PolarHBondContact N-O 2.67Å; V527-L714 HydrophobicContact CB-CB 4.33Å; V527-L714 HydrophobicContact CB-CD1 4.21Å; V527-L714 HydrophobicContact CB-CG 4.23Å; V527-L714 HydrophobicContact CG1-CD1 4.1Å; V527-L714 HydrophobicContact CG1-CG 4.48Å; V527-L715 PolarHBondContact O-N 3.06Å; V527-V727 HydrophobicContact CG2-CG1 4.43Å
528I98.3Very high97.5Very high0 Ų015.4 Ų15.40%08%0.077CC..EExtended strand (participates in β ladder)trans-105.9112.6165.8-70.2176.1000108.2L497 L498 V499 G500 C530 I543 M682 A683 V686L497-I528 HydrophobicContact CD1-CB 4.47Å; L497-I528 HydrophobicContact CD1-CD1 3.94Å; L497-I528 HydrophobicContact CD1-CG1 3.89Å; L497-I528 HydrophobicContact CD2-CD1 4.11Å; L498-I528 PolarHBondContact O-N 3.28Å; V499-I528 HydrophobicContact CG1-CG2 4.44Å; V499-I528 HydrophobicContact CG2-CB 4.41Å; G500-I528 PolarHBondContact N-O 3.29Å; I528-C530 PolarHBondContact O-N 3.02Å; I528-I543 HydrophobicContact CG2-CD1 3.34Å; I528-M682 HydrophobicContact CD1-CB 4.27Å; I528-M682 HydrophobicContact CG2-CB 4.34Å; I528-M682 HydrophobicContact CG2-CE 4.2Å; I528-M682 HydrophobicContact CG2-SD 4.43Å; I528-A683 HydrophobicContact CD1-CB 4.22Å; I528-V686 HydrophobicContact CD1-CB 4.13Å; I528-V686 HydrophobicContact CD1-CG2 3.87Å; I528-V686 HydrophobicContact CG1-CB 4.44Å; I528-V686 HydrophobicContact CG1-CG2 3.73Å
529P98.1Very high97.3Very high0 Ų014.2 Ų14.20%07%0.074CC..EExtended strand (participates in β ladder)trans-61.1115176.6-25.936.7000112.4G500 V536 A539 I543 L714 L715G500-P529 CarbonylContact O-C 3.5Å; G500-P529 WeakPolarHBondContact O-CA 3.22Å; P529-V536 HydrophobicContact CB-CB 4.02Å; P529-V536 HydrophobicContact CB-CG1 4.08Å; P529-V536 HydrophobicContact CB-CG2 4.25Å; P529-V536 HydrophobicContact CG-CB 4.44Å; P529-V536 HydrophobicContact CG-CG1 4.03Å; P529-A539 HydrophobicContact CB-CB 4.15Å; P529-A539 HydrophobicContact CG-CB 3.8Å; P529-I543 PolarHBondContact O-N 2.95Å; P529-L714 HydrophobicContact CG-CD1 4.12Å; P529-L714 HydrophobicContact CG-CD2 3.81Å; P529-L714 HydrophobicContact CG-CG 3.97Å; P529-L715 WeakPolarHBondContact CD-O 3.45Å
530C98Very high97.1Very high0 Ų08.2 Ų8.20%05%0.049CC..BIsolated β-bridgetrans-139.399.7-179.8-167.70000110.1M418 V499 G500 G501 I528 I543M418-C530 HydrophobicContact CE-CB 4.46Å; M418-C530 HydrophobicContact CG-CB 4.3Å; M418-C530 WeakPolarHBondContact CG-SG 3.08Å; V499-C530 HydrophobicContact CG1-CB 3.75Å; G500-C530 CarbonylContact C-O 3.6Å; G500-C530 WeakPolarHBondContact CA-O 3.24Å; G500-C530 PolarHBondContact O-N 2.95Å; G501-C530 PolarHBondContact N-O 3.26Å; G501-C530 VanDerWaalsContact N-O 3.15Å; I528-C530 PolarHBondContact O-N 3.02Å; C530-I543 CarbonylContact C-O 3.49Å; C530-I543 WeakPolarHBondContact CA-O 3.32Å; C530-I543 HydrophobicContact CB-CB 4.1Å; C530-I543 PolarHBondContact SG-O 3.13Å
531T97.7Very high96.9Very high13 Ų136.7 Ų6.78%0.084%0.041CC..  trans-163.5150.9-178.4175.90000109.1S533 V536 S542 I543T531-S533 VanDerWaalsContact C-N 3.33Å; T531-S533 PolarHBondContact OG1-N 3.32Å; T531-V536 HydrophobicContact CG2-CG2 3.79Å; T531-S542 PolarHBondContact O-OG 2.78Å; T531-I543 PolarHBondContact N-O 3.09Å
532I97.7Very high96.8Very high10 Ų106.7 Ų6.75%0.0514%0.041CC..SBendtrans-72.6-28.6174.465.3172000112.3N534 A548 M576 L583 Q666 Q667I532-N534 VanDerWaalsContact C-N 3.29Å; I532-N534 PolarHBondContact O-N 3.21Å; I532-A548 HydrophobicContact CB-CB 3.7Å; I532-A548 HydrophobicContact CG2-CB 3.81Å; I532-M576 HydrophobicContact CD1-CB 4.15Å; I532-M576 HydrophobicContact CD1-CE 4.35Å; I532-M576 HydrophobicContact CD1-SD 4.01Å; I532-L583 HydrophobicContact CB-CD1 4.35Å; I532-L583 HydrophobicContact CD1-CD1 4.38Å; I532-L583 HydrophobicContact CG1-CD1 4.28Å; I532-L583 WeakPolarHBondContact O-CD1 3.42Å; I532-L583 WeakPolarHBondContact O-CD2 3.38Å; I532-L583 WeakPolarHBondContact O-CG 3.21Å; I532-Q666 HydrophobicContact CD1-CB 4.19Å; I532-Q667 HydrophobicContact CD1-CG 4.22Å
533S97.7Very high96.8Very high18 Ų186.7 Ų6.713%0.1264%0.041CC..SBendtrans-74.7-17.2-171.5-52.80000114.1T531 N535 C580T531-S533 VanDerWaalsContact C-N 3.33Å; T531-S533 PolarHBondContact OG1-N 3.32Å; S533-N535 VanDerWaalsContact C-N 3.25Å; S533-N535 PolarHBondContact O-N 2.88Å; S533-C580 PolarHBondContact O-SG 3.29Å
534N97.4Very high96.8Very high5 Ų56.4 Ų6.43%0.0274%0.039CC..  trans49.544.7-173.1-163.438.2000113.9I532 N540 Y541 S542 Y582I532-N534 VanDerWaalsContact C-N 3.29Å; I532-N534 PolarHBondContact O-N 3.21Å; N534-N540 PolarHBondContact ND2-O 3.18Å; N534-Y541 VanDerWaalsContact OD1-C 3.27Å; N534-Y541 VanDerWaalsContact OD1-CA 3.26Å; N534-Y541 WeakPolarHBondContact OD1-CA 3.31Å; N534-S542 WeakPolarHBondContact CA-OG 3.49Å; N534-S542 PolarHBondContact N-OG 2.8Å; N534-S542 PolarHBondContact OD1-N 3.31Å; N534-S542 PolarHBondContact OD1-OG 3.29Å; N534-Y582 HydrophobicContact CB-CD1 3.6Å; N534-Y582 HydrophobicContact CB-CD2 3.98Å; N534-Y582 HydrophobicContact CB-CE1 3.83Å; N534-Y582 HydrophobicContact CB-CE2 4.15Å; N534-Y582 HydrophobicContact CB-CG 3.7Å; N534-Y582 WeakPolarHBondContact ND2-CD2 3.36Å; N534-Y582 WeakPolarHBondContact ND2-CE2 3.46Å
535N97Very high96.7Very high11 Ų116.4 Ų6.46%0.0594%0.04CC..  trans-109.420.2-174.174.3-45.3000113.1S533 C580 R739 L740S533-N535 VanDerWaalsContact C-N 3.25Å; S533-N535 PolarHBondContact O-N 2.88Å; N535-C580 HydrophobicContact CB-CB 3.78Å; N535-R739 PolarHBondContact ND2-O 3.37Å; N535-L740 HydrophobicContact CB-CD2 4.4Å
536V96.5Very high96.7Very high1 Ų16.7 Ų6.71%0.0064%0.041CC..  trans-96.4123.5-177.8-174.90000109.6Y505 P529 T531 L714Y505-V536 HydrophobicContact CG-CG1 4.49Å; P529-V536 HydrophobicContact CB-CB 4.02Å; P529-V536 HydrophobicContact CB-CG1 4.08Å; P529-V536 HydrophobicContact CB-CG2 4.25Å; P529-V536 HydrophobicContact CG-CB 4.44Å; P529-V536 HydrophobicContact CG-CG1 4.03Å; T531-V536 HydrophobicContact CG2-CG2 3.79Å; V536-L714 HydrophobicContact CG1-CD1 3.65Å
537P95.3Very high96.7Very high2 Ų27 Ų71%0.0134%0.043CC..THydrogen-bonded Turntrans-55.9147175.3-2534.2000113.8F502 Y505 A539 L714 L730 T734 P741F502-P537 HydrophobicContact CE2-CG 4.32Å; Y505-P537 HydrophobicContact CD1-CG 4.42Å; Y505-P537 HydrophobicContact CE1-CB 4.47Å; Y505-P537 HydrophobicContact CE1-CG 3.85Å; P537-A539 VanDerWaalsContact C-N 3.3Å; P537-A539 PolarHBondContact O-N 3.12Å; P537-L714 WeakPolarHBondContact O-CD1 3.44Å; P537-L714 WeakPolarHBondContact O-CD2 3.29Å; P537-L730 HydrophobicContact CB-CB 4.29Å; P537-T734 HydrophobicContact CG-CG2 3.85Å; P537-T734 VanDerWaalsContact CG-OG1 3.27Å; P537-T734 WeakPolarHBondContact CG-OG1 3.47Å; P537-P741 HydrophobicContact CB-CB 4.35Å; P537-P741 HydrophobicContact CG-CB 4.31Å
538G93.6Very high96.7Very high14 Ų147 Ų714%0.1444%0.043CC..THydrogen-bonded Turntrans79.92.1178.200000115.2G716 L718G538-G716 WeakPolarHBondContact O-CA 3.34Å; G538-L718 WeakPolarHBondContact O-CD1 3.36Å; G538-L718 VanDerWaalsContact O-CG 3.29Å; G538-L718 WeakPolarHBondContact O-CG 3.23Å
539A93.7Very high96.7Very high11 Ų117.1 Ų7.19%0.0914%0.044CC..  trans-133.7126.2176.600000112.1P529 P537 Y541 L714P529-A539 HydrophobicContact CB-CB 4.15Å; P529-A539 HydrophobicContact CG-CB 3.8Å; P537-A539 VanDerWaalsContact C-N 3.3Å; P537-A539 PolarHBondContact O-N 3.12Å; A539-Y541 PolarHBondContact O-N 3.38Å; A539-L714 HydrophobicContact CB-CD2 4.47Å
540N92.7Very high96.7Very high23 Ų238.8 Ų8.812%0.1235%0.052CC..SBendtrans-72.2-23.2174.3-73.6-4000112.4N534 V717 H719 W745N534-N540 PolarHBondContact ND2-O 3.18Å; N540-V717 VanDerWaalsContact CB-O 3.26Å; N540-V717 WeakPolarHBondContact CB-O 3.45Å; N540-V717 PolarHBondContact N-O 2.97Å; N540-H719 PolarHBondContact ND2-N 3.32Å; N540-W745 VanDerWaalsContact CB-CD1 3.5Å; N540-W745 HydrophobicContact CB-CG 4.3Å; N540-W745 VanDerWaalsContact CG-CD1 3.4Å; N540-W745 PolarHBondContact O-NE1 3.48Å
541Y93.2Very high96.7Very high23 Ų2310.3 Ų10.39%0.096%0.062CC..  trans-139.6129.8-179-55.2-82.7000109N339 N534 A539 M678 V717 W745N339-Y541 HydrophobicContact CB-CE2 3.65Å; N339-Y541 VanDerWaalsContact ND2-CE2 3.33Å; N339-Y541 WeakPolarHBondContact ND2-CE2 3.28Å; N534-Y541 VanDerWaalsContact OD1-C 3.27Å; N534-Y541 VanDerWaalsContact OD1-CA 3.26Å; N534-Y541 WeakPolarHBondContact OD1-CA 3.31Å; A539-Y541 PolarHBondContact O-N 3.38Å; Y541-M678 WeakPolarHBondContact O-CE 3.21Å; Y541-V717 HydrophobicContact CD2-CG1 4.45Å; Y541-W745 HydrophobicContact CD1-CZ2 4.18Å; Y541-W745 AromaticContact CE1-CH2 3.86Å; Y541-W745 HydrophobicContact CE1-CH2 3.86Å; Y541-W745 AromaticContact CE1-CZ2 3.31Å; Y541-W745 HydrophobicContact CE1-CZ2 3.31Å; Y541-W745 HydrophobicContact CE2-CZ2 4.47Å; Y541-W745 AromaticContact CZ-CH2 3.88Å; Y541-W745 AromaticContact CZ-CZ2 3.48Å; Y541-W745 VanDerWaalsContact CZ-CZ2 3.48Å; Y541-W745 VanDerWaalsContact OH-CH2 3.25Å; Y541-W745 WeakPolarHBondContact OH-CH2 2.93Å; Y541-W745 WeakPolarHBondContact OH-CZ2 3.48Å
542S96.3Very high96.7Very high0 Ų09.7 Ų9.70%06%0.058CC..  trans-101.6146.1168.758.70000110.3T531 N534 G544 S545T531-S542 PolarHBondContact O-OG 2.78Å; N534-S542 WeakPolarHBondContact CA-OG 3.49Å; N534-S542 PolarHBondContact N-OG 2.8Å; N534-S542 PolarHBondContact OD1-N 3.31Å; N534-S542 PolarHBondContact OD1-OG 3.29Å; S542-G544 PolarHBondContact O-N 3.03Å; S542-S545 VanDerWaalsContact O-CB 3.31Å; S542-S545 WeakPolarHBondContact O-CB 3.33Å; S542-S545 PolarHBondContact O-N 3.41Å; S542-S545 PolarHBondContact O-OG 3.13Å
543I97.8Very high96.7Very high0 Ų09.2 Ų9.20%06%0.056CC..BIsolated β-bridgetrans-62.1134.8174.3-62.1159.3000109.4S415 C416 I528 P529 C530 T531 D675 M678 A679 M682S415-I543 PolarHBondContact OG-O 3.31Å; C416-I543 WeakPolarHBondContact O-CG2 3.18Å; I528-I543 HydrophobicContact CG2-CD1 3.34Å; P529-I543 PolarHBondContact O-N 2.95Å; C530-I543 CarbonylContact C-O 3.49Å; C530-I543 WeakPolarHBondContact CA-O 3.32Å; C530-I543 HydrophobicContact CB-CB 4.1Å; C530-I543 PolarHBondContact SG-O 3.13Å; T531-I543 PolarHBondContact N-O 3.09Å; I543-D675 HydrophobicContact CG2-CB 4.42Å; I543-M678 HydrophobicContact CG1-CB 4.48Å; I543-M678 HydrophobicContact CG1-CG 3.99Å; I543-M678 HydrophobicContact CG1-SD 4.39Å; I543-A679 HydrophobicContact CD1-CB 3.85Å; I543-A679 HydrophobicContact CG1-CB 4.32Å; I543-A679 HydrophobicContact CG2-CB 3.95Å; I543-M682 HydrophobicContact CD1-SD 3.91Å; I543-M682 HydrophobicContact CG1-SD 4.06Å
544G97.6Very high96.7Very high0 Ų010.8 Ų10.80%07%0.067CC..THydrogen-bonded Turntrans95.7-14-17800000113.9S415 C416 S542 A548 D675S415-G544 WeakPolarHBondContact OG-CA 3.33Å; C416-G544 VanDerWaalsContact O-CA 3.27Å; C416-G544 WeakPolarHBondContact O-CA 3.11Å; C416-G544 PolarHBondContact O-N 3.25Å; S542-G544 PolarHBondContact O-N 3.03Å; G544-A548 PolarHBondContact O-N 3.13Å; G544-A548 VanDerWaalsContact O-N 3.09Å; G544-D675 VanDerWaalsContact C-OD2 3.29Å; G544-D675 VanDerWaalsContact CA-CG 3.45Å; G544-D675 WeakPolarHBondContact CA-OD2 3.34Å; G544-D675 PolarHBondContact N-OD1 2.94Å; G544-D675 PolarHBondContact N-OD2 3.04Å
545S97.4Very high96.7Very high1 Ų113 Ų131%0.0078%0.077CC..Hα-helixtrans-68.6-35.2179.267.10000112.3S542 A548 L549S542-S545 VanDerWaalsContact O-CB 3.31Å; S542-S545 WeakPolarHBondContact O-CB 3.33Å; S542-S545 PolarHBondContact O-N 3.41Å; S542-S545 PolarHBondContact O-OG 3.13Å; S545-A548 PolarHBondContact O-N 3.49Å; S545-L549 VanDerWaalsContact O-CG 3.27Å; S545-L549 WeakPolarHBondContact O-CG 3.44Å; S545-L549 PolarHBondContact O-N 2.87Å
546D98.1Very high96.6Very high7 Ų712.5 Ų12.54%0.0378%0.075CC..Hα-helixtrans-68.6-42.6176175.974.1000111.9A548 L549 N550 S672 F674D546-A548 VanDerWaalsContact C-N 3.29Å; D546-A548 PolarHBondContact O-N 2.83Å; D546-L549 PolarHBondContact O-N 2.95Å; D546-N550 PolarHBondContact O-N 3.5Å; D546-N550 PolarHBondContact O-ND2 3.36Å; D546-N550 PolarHBondContact OD1-ND2 3.25Å; D546-N550 PolarHBondContact OD2-ND2 3.16Å; D546-N550 VanDerWaalsContact OD2-ND2 3.1Å; D546-S672 WeakPolarHBondContact OD2-CB 3.4Å; D546-S672 PolarHBondContact OD2-OG 3.11Å; D546-F674 HydrophobicContact CB-CB 4.2Å; D546-F674 HydrophobicContact CB-CD1 3.75Å; D546-F674 HydrophobicContact CB-CG 4.22Å
547T98.3Very high96.6Very high7 Ų713.4 Ų13.44%0.0438%0.08CC..Hα-helixtrans-58-45.4174.5-57.90000110.5C416 L549 N550 V551 S672 D675C416-T547 HydrophobicContact CB-CG2 3.95Å; T547-L549 PolarHBondContact O-N 2.93Å; T547-N550 PolarHBondContact O-N 3.42Å; T547-V551 WeakPolarHBondContact O-CG2 3.26Å; T547-V551 PolarHBondContact O-N 2.99Å; T547-S672 PolarHBondContact OG1-N 2.81Å; T547-S672 PolarHBondContact OG1-OG 2.98Å; T547-D675 VanDerWaalsContact CB-OD2 3.23Å; T547-D675 WeakPolarHBondContact CB-OD2 3.29Å; T547-D675 PolarHBondContact N-OD2 3.37Å; T547-D675 PolarHBondContact OG1-OD2 3.38Å
548A98.3Very high96.5Very high0 Ų019.4 Ų19.40%011%0.106CC..Hα-helixtrans-61-45177.400000112.3I532 G544 S545 D546 N550 V551 I552 L583 Q666I532-A548 HydrophobicContact CB-CB 3.7Å; I532-A548 HydrophobicContact CG2-CB 3.81Å; G544-A548 PolarHBondContact O-N 3.13Å; G544-A548 VanDerWaalsContact O-N 3.09Å; S545-A548 PolarHBondContact O-N 3.49Å; D546-A548 VanDerWaalsContact C-N 3.29Å; D546-A548 PolarHBondContact O-N 2.83Å; A548-N550 VanDerWaalsContact C-N 3.34Å; A548-N550 PolarHBondContact O-N 3.3Å; A548-V551 PolarHBondContact O-N 2.81Å; A548-I552 VanDerWaalsContact O-CG1 3.25Å; A548-I552 WeakPolarHBondContact O-CG1 3.22Å; A548-I552 PolarHBondContact O-N 3.5Å; A548-L583 HydrophobicContact CB-CD1 4.47Å; A548-L583 HydrophobicContact CB-CD2 3.93Å; A548-Q666 WeakPolarHBondContact CA-O 3.28Å; A548-Q666 WeakPolarHBondContact CB-O 3.37Å
549L98.4Very high96.5Very high4 Ų419.7 Ų19.72%0.02110%0.104CC..Hα-helixtrans-59.5-43176.6-72.3173000112.1A302 L306 S545 D546 T547 V551 I552 C553 Y582 L583 L586 A587A302-L549 HydrophobicContact CB-CB 3.73Å; L306-L549 HydrophobicContact CD1-CD1 4.29Å; S545-L549 VanDerWaalsContact O-CG 3.27Å; S545-L549 WeakPolarHBondContact O-CG 3.44Å; S545-L549 PolarHBondContact O-N 2.87Å; D546-L549 PolarHBondContact O-N 2.95Å; T547-L549 PolarHBondContact O-N 2.93Å; L549-V551 PolarHBondContact O-N 2.85Å; L549-I552 PolarHBondContact O-N 3Å; L549-C553 WeakPolarHBondContact O-CB 3.46Å; L549-C553 PolarHBondContact O-N 2.91Å; L549-C553 PolarHBondContact O-SG 3.1Å; L549-Y582 HydrophobicContact CD1-CE1 3.97Å; L549-Y582 HydrophobicContact CG-CE1 4.38Å; L549-L583 HydrophobicContact CD2-CD2 3.82Å; L549-L583 HydrophobicContact CG-CD2 4.01Å; L549-L586 HydrophobicContact CD1-CB 4.24Å; L549-L586 HydrophobicContact CD1-CD1 4.23Å; L549-L586 HydrophobicContact CD2-CB 3.71Å; L549-A587 HydrophobicContact CD2-CB 3.95Å
550N98.4Very high96.3Very high34 Ų3419.3 Ų19.318%0.18210%0.1CC..Hα-helixtrans-61.9-42176.5-81.4-72000112.1S301 A302 D546 T547 A548 C553 S554S301-N550 WeakPolarHBondContact CA-OD1 3.48Å; S301-N550 WeakPolarHBondContact CB-OD1 3.39Å; A302-N550 PolarHBondContact N-OD1 2.95Å; D546-N550 PolarHBondContact O-N 3.5Å; D546-N550 PolarHBondContact O-ND2 3.36Å; D546-N550 PolarHBondContact OD1-ND2 3.25Å; D546-N550 PolarHBondContact OD2-ND2 3.16Å; D546-N550 VanDerWaalsContact OD2-ND2 3.1Å; T547-N550 PolarHBondContact O-N 3.42Å; A548-N550 VanDerWaalsContact C-N 3.34Å; A548-N550 PolarHBondContact O-N 3.3Å; N550-C553 PolarHBondContact O-N 3.48Å; N550-S554 WeakPolarHBondContact O-CB 3.47Å; N550-S554 PolarHBondContact O-N 2.93Å
551V97.9Very high96.1Very high32 Ų3225.2 Ų25.219%0.19413%0.127CC..Hα-helixtrans-62.6-48.5175.5174.80000111.2T547 A548 L549 C553 S554 M555 A665T547-V551 WeakPolarHBondContact O-CG2 3.26Å; T547-V551 PolarHBondContact O-N 2.99Å; A548-V551 PolarHBondContact O-N 2.81Å; L549-V551 PolarHBondContact O-N 2.85Å; V551-C553 VanDerWaalsContact C-N 3.33Å; V551-C553 PolarHBondContact O-N 3.26Å; V551-S554 WeakPolarHBondContact O-CB 3.37Å; V551-S554 PolarHBondContact O-N 2.84Å; V551-M555 HydrophobicContact CG1-CE 3.98Å; V551-M555 HydrophobicContact CG1-CG 4.48Å; V551-M555 HydrophobicContact CG1-SD 4.21Å; V551-M555 WeakPolarHBondContact O-CG 2.97Å; V551-M555 PolarHBondContact O-N 3.31Å; V551-A665 WeakPolarHBondContact CG1-O 3.42Å
552I98.2Very high95.9Very high0 Ų027.1 Ų27.10%014%0.143CC..Hα-helixtrans-60.4-45.9-179.9-61.2161.7000109.7A548 L549 S554 M555 V556 T575 L583 A587 L662 Q666A548-I552 VanDerWaalsContact O-CG1 3.25Å; A548-I552 WeakPolarHBondContact O-CG1 3.22Å; A548-I552 PolarHBondContact O-N 3.5Å; L549-I552 PolarHBondContact O-N 3Å; I552-S554 PolarHBondContact O-N 2.94Å; I552-M555 PolarHBondContact O-N 2.91Å; I552-V556 HydrophobicContact CG2-CG2 4.18Å; I552-V556 VanDerWaalsContact O-CG2 3.3Å; I552-V556 WeakPolarHBondContact O-CG2 3.35Å; I552-V556 PolarHBondContact O-N 3.01Å; I552-T575 HydrophobicContact CD1-CG2 4.18Å; I552-T575 HydrophobicContact CG2-CG2 4.05Å; I552-L583 HydrophobicContact CD1-CB 3.93Å; I552-L583 HydrophobicContact CD1-CD1 4.27Å; I552-L583 HydrophobicContact CD1-CD2 4.05Å; I552-L583 HydrophobicContact CD1-CG 4.31Å; I552-A587 HydrophobicContact CB-CB 3.82Å; I552-A587 HydrophobicContact CD1-CB 4.24Å; I552-A587 HydrophobicContact CG2-CB 3.36Å; I552-L662 HydrophobicContact CB-CD1 4.2Å; I552-L662 HydrophobicContact CG1-CD1 3.97Å; I552-L662 HydrophobicContact CG2-CD1 3.82Å; I552-Q666 HydrophobicContact CD1-CG 4.32Å; I552-Q666 HydrophobicContact CG1-CG 3.83Å
553C97.9Very high95.3Very high1 Ų127.1 Ų27.11%0.00714%0.144CC..Hα-helixtrans-59.3-45.2177.3-67.50000111.9L549 N550 V551 M555 V556 D557 S591L549-C553 WeakPolarHBondContact O-CB 3.46Å; L549-C553 PolarHBondContact O-N 2.91Å; L549-C553 PolarHBondContact O-SG 3.1Å; N550-C553 PolarHBondContact O-N 3.48Å; V551-C553 VanDerWaalsContact C-N 3.33Å; V551-C553 PolarHBondContact O-N 3.26Å; C553-M555 VanDerWaalsContact C-N 3.3Å; C553-M555 PolarHBondContact O-N 3.32Å; C553-V556 PolarHBondContact O-N 3.3Å; C553-D557 WeakPolarHBondContact O-CB 3.43Å; C553-D557 PolarHBondContact O-N 2.9Å; C553-S591 WeakPolarHBondContact CA-OG 3.31Å; C553-S591 PolarHBondContact SG-OG 2.91Å
554S96.8Very high94.3Very high51 Ų5133.1 Ų33.136%0.35717%0.166SC..Hα-helixtrans-59.1-40.9176.3-177.30000112.3N550 V551 I552 K558N550-S554 WeakPolarHBondContact O-CB 3.47Å; N550-S554 PolarHBondContact O-N 2.93Å; V551-S554 WeakPolarHBondContact O-CB 3.37Å; V551-S554 PolarHBondContact O-N 2.84Å; I552-S554 PolarHBondContact O-N 2.94Å; S554-K558 WeakPolarHBondContact O-CD 3.49Å; S554-K558 WeakPolarHBondContact O-CG 3.44Å; S554-K558 PolarHBondContact O-N 3.37Å; S554-K558 PolarHBondContact OG-NZ 2.93Å
555M96.8Very high93.2Very high51 Ų5136.5 Ų36.525%0.25120%0.201SC..Hα-helixtrans-67.7-46.8176.7-69.9-173.8169.600111.5V551 I552 C553 D557 K558 L559 L662 A665V551-M555 HydrophobicContact CG1-CE 3.98Å; V551-M555 HydrophobicContact CG1-CG 4.48Å; V551-M555 HydrophobicContact CG1-SD 4.21Å; V551-M555 WeakPolarHBondContact O-CG 2.97Å; V551-M555 PolarHBondContact O-N 3.31Å; I552-M555 PolarHBondContact O-N 2.91Å; C553-M555 VanDerWaalsContact C-N 3.3Å; C553-M555 PolarHBondContact O-N 3.32Å; M555-D557 VanDerWaalsContact C-N 3.29Å; M555-D557 PolarHBondContact O-N 3.48Å; M555-K558 WeakPolarHBondContact O-CB 3.39Å; M555-K558 PolarHBondContact O-N 3.03Å; M555-L559 WeakPolarHBondContact O-CG 3.45Å; M555-L559 PolarHBondContact O-N 3.09Å; M555-L662 HydrophobicContact CB-CD1 4.35Å; M555-L662 HydrophobicContact CB-CD2 4.13Å; M555-L662 HydrophobicContact SD-CB 4.02Å; M555-L662 HydrophobicContact SD-CD1 3.96Å; M555-L662 HydrophobicContact SD-CD2 3.61Å; M555-L662 HydrophobicContact SD-CG 4.05Å; M555-A665 HydrophobicContact CE-CB 3.37Å
556V96.2Very high92.2Very high0 Ų038.9 Ų38.90%022%0.215CC..Hα-helixtrans-60.5-39.6177.5176.20000111.1I552 C553 K558 L559 K560 V573 I627I552-V556 HydrophobicContact CG2-CG2 4.18Å; I552-V556 VanDerWaalsContact O-CG2 3.3Å; I552-V556 WeakPolarHBondContact O-CG2 3.35Å; I552-V556 PolarHBondContact O-N 3.01Å; C553-V556 PolarHBondContact O-N 3.3Å; V556-K558 VanDerWaalsContact C-N 3.35Å; V556-K558 PolarHBondContact O-N 3.4Å; V556-L559 CarbonylContact O-C 3.53Å; V556-L559 WeakPolarHBondContact O-CB 3.31Å; V556-L559 PolarHBondContact O-N 3.2Å; V556-L559 VanDerWaalsContact O-N 3.11Å; V556-K560 WeakPolarHBondContact O-CG 3.31Å; V556-K560 PolarHBondContact O-N 3.49Å; V556-V573 HydrophobicContact CG2-CG1 4.26Å; V556-V573 HydrophobicContact CG2-CG2 4.43Å; V556-I627 HydrophobicContact CG1-CD1 3.84Å; V556-I627 HydrophobicContact CG1-CG2 4.14Å
557D95Very high91.1Very high21 Ų2146.7 Ų46.711%0.11225%0.249CC..Hα-helixtrans-63.6-38.9177.4-69.5-25.4000112.5Q73 R305 C553 M555 L559 K560 Q561Q73-D557 HydrophobicContact CB-CB 4.44Å; Q73-D557 VanDerWaalsContact CB-CG 3.46Å; Q73-D557 WeakPolarHBondContact CB-OD1 3.42Å; Q73-D557 WeakPolarHBondContact CB-OD2 3.4Å; R305-D557 IonicContact CZ-OD2 3.52Å; R305-D557 VanDerWaalsContact CZ-OD2 3.23Å; R305-D557 IonicContact NH1-OD1 3.97Å; R305-D557 PolarHBondContact NH1-OD1 3Å; R305-D557 IonicContact NH1-OD2 2.74Å; R305-D557 PolarHBondContact NH1-OD2 3.34Å; R305-D557 IonicContact NH2-OD2 3.49Å; R305-D557 PolarHBondContact NH2-OD2 3.22Å; C553-D557 WeakPolarHBondContact O-CB 3.43Å; C553-D557 PolarHBondContact O-N 2.9Å; M555-D557 VanDerWaalsContact C-N 3.29Å; M555-D557 PolarHBondContact O-N 3.48Å; D557-L559 VanDerWaalsContact C-N 3.32Å; D557-L559 PolarHBondContact O-N 3.46Å; D557-K560 WeakPolarHBondContact O-CB 3.23Å; D557-K560 PolarHBondContact O-N 3.19Å; D557-K560 IonicContact OD1-NZ 3.51Å; D557-K560 PolarHBondContact OD1-NZ 3.09Å; D557-Q561 PolarHBondContact O-N 3.13Å
558K94Very high90.6Very high128 Ų12849 Ų4956%0.55726%0.259SS*.Hα-helixtrans-63.7-38172.2-68.4162.3-176159.80111.6S554 M555 V556 Q561 S562S554-K558 WeakPolarHBondContact O-CD 3.49Å; S554-K558 WeakPolarHBondContact O-CG 3.44Å; S554-K558 PolarHBondContact O-N 3.37Å; S554-K558 PolarHBondContact OG-NZ 2.93Å; M555-K558 WeakPolarHBondContact O-CB 3.39Å; M555-K558 PolarHBondContact O-N 3.03Å; V556-K558 VanDerWaalsContact C-N 3.35Å; V556-K558 PolarHBondContact O-N 3.4Å; K558-Q561 PolarHBondContact O-N 3.37Å; K558-S562 PolarHBondContact O-N 2.93Å
559L92.7Very high90.3Very high20 Ų2051 Ų5111%0.10527%0.267CS..Hα-helixtrans-66.7-40.5175.2-63.6177.8000112M555 V556 D557 Q561 S562 A563 F571 V573 N660M555-L559 WeakPolarHBondContact O-CG 3.45Å; M555-L559 PolarHBondContact O-N 3.09Å; V556-L559 CarbonylContact O-C 3.53Å; V556-L559 WeakPolarHBondContact O-CB 3.31Å; V556-L559 PolarHBondContact O-N 3.2Å; V556-L559 VanDerWaalsContact O-N 3.11Å; D557-L559 VanDerWaalsContact C-N 3.32Å; D557-L559 PolarHBondContact O-N 3.46Å; L559-Q561 VanDerWaalsContact C-N 3.3Å; L559-Q561 PolarHBondContact O-N 3.39Å; L559-S562 WeakPolarHBondContact O-CB 3.46Å; L559-S562 PolarHBondContact O-N 3.25Å; L559-A563 PolarHBondContact O-N 3.49Å; L559-F571 HydrophobicContact CB-CD2 4.3Å; L559-F571 HydrophobicContact CB-CE2 4.41Å; L559-F571 HydrophobicContact CB-CG 4.41Å; L559-F571 HydrophobicContact CD1-CD1 4.49Å; L559-F571 HydrophobicContact CD2-CD1 4.28Å; L559-F571 HydrophobicContact CD2-CE1 4.02Å; L559-F571 HydrophobicContact CD2-CZ 4.36Å; L559-F571 WeakPolarHBondContact O-CE2 3.37Å; L559-V573 HydrophobicContact CD1-CG2 3.55Å; L559-N660 HydrophobicContact CD1-CB 3.99Å; L559-N660 WeakPolarHBondContact CD2-ND2 3.37Å
560K90.4Very high90.1Very high2 Ų250.8 Ų50.81%0.00927%0.266CS..Hα-helixtrans-58.4-44.7172.3-67.4176.3-171.7159.20111.3V556 D557 S562 A563 R564 S591 I627V556-K560 WeakPolarHBondContact O-CG 3.31Å; V556-K560 PolarHBondContact O-N 3.49Å; D557-K560 WeakPolarHBondContact O-CB 3.23Å; D557-K560 PolarHBondContact O-N 3.19Å; D557-K560 IonicContact OD1-NZ 3.51Å; D557-K560 PolarHBondContact OD1-NZ 3.09Å; K560-S562 VanDerWaalsContact C-N 3.32Å; K560-S562 PolarHBondContact O-N 3.03Å; K560-A563 WeakPolarHBondContact O-CB 3.36Å; K560-A563 PolarHBondContact O-N 3.46Å; K560-A563 VanDerWaalsContact O-N 3.16Å; K560-R564 PolarHBondContact O-N 3.14Å; K560-R564 VanDerWaalsContact O-N 3.13Å; K560-S591 WeakPolarHBondContact CE-O 3.33Å; K560-S591 PolarHBondContact NZ-O 2.99Å; K560-I627 HydrophobicContact CB-CD1 4.49Å; K560-I627 HydrophobicContact CD-CD1 4.48Å; K560-I627 HydrophobicContact CG-CD1 3.4Å; K560-I627 VanDerWaalsContact CG-CD1 3.4Å
561Q88.2Confident90Very high147 Ų14749.6 Ų49.669%0.68726%0.259SS*.Hα-helixtrans-61.9-42.5177.9-172.5177.33.800111.2D557 K558 L559 A563 R564D557-Q561 PolarHBondContact O-N 3.13Å; K558-Q561 PolarHBondContact O-N 3.37Å; L559-Q561 VanDerWaalsContact C-N 3.3Å; L559-Q561 PolarHBondContact O-N 3.39Å; Q561-A563 VanDerWaalsContact C-N 3.32Å; Q561-A563 PolarHBondContact O-N 3.31Å; Q561-R564 PolarHBondContact O-N 2.65Å
562S88.3Confident90Very high63 Ų6348.1 Ų48.144%0.44125%0.25SC..Hα-helixtrans-60.6-40.4173.2-177.50000112.3K558 L559 K560 R564 G565K558-S562 PolarHBondContact O-N 2.93Å; L559-S562 WeakPolarHBondContact O-CB 3.46Å; L559-S562 PolarHBondContact O-N 3.25Å; K560-S562 VanDerWaalsContact C-N 3.32Å; K560-S562 PolarHBondContact O-N 3.03Å; S562-R564 VanDerWaalsContact C-N 3.31Å; S562-R564 PolarHBondContact O-N 3.06Å; S562-G565 PolarHBondContact O-N 3.48Å
563A84.3Confident90Very high1 Ų148.1 Ų48.11%0.00825%0.25CC..Hα-helixtrans-62-35.8178.100000112.4L559 K560 Q561 G565 T566 R569 F571 R625L559-A563 PolarHBondContact O-N 3.49Å; K560-A563 WeakPolarHBondContact O-CB 3.36Å; K560-A563 PolarHBondContact O-N 3.46Å; K560-A563 VanDerWaalsContact O-N 3.16Å; Q561-A563 VanDerWaalsContact C-N 3.32Å; Q561-A563 PolarHBondContact O-N 3.31Å; A563-G565 PolarHBondContact O-N 3.25Å; A563-T566 CarbonylContact O-C 3.45Å; A563-T566 PolarHBondContact O-N 2.79Å; A563-R569 HydrophobicContact CB-CB 4.5Å; A563-F571 HydrophobicContact CB-CD2 4.36Å; A563-F571 HydrophobicContact CB-CE2 3.87Å; A563-R625 HydrophobicContact CB-CB 3.67Å
564R77.3Confident90Very high126 Ų12649.9 Ų49.948%0.47526%0.258SS..Hα-helixtrans-62-28.6178.9-71.1-177.7176.4-177.11.6113.4D70 Y74 K560 Q561 S562 T566D70-R564 IonicContact OD2-CZ 2.88Å; D70-R564 IonicContact OD2-NE 3.65Å; D70-R564 PolarHBondContact OD2-NE 3.22Å; D70-R564 IonicContact OD2-NH2 3.66Å; D70-R564 PolarHBondContact OD2-NH2 3.23Å; Y74-R564 PolarHBondContact OH-NH1 2.75Å; Y74-R564 PolarHBondContact OH-NH2 2.83Å; K560-R564 PolarHBondContact O-N 3.14Å; K560-R564 VanDerWaalsContact O-N 3.13Å; Q561-R564 PolarHBondContact O-N 2.65Å; S562-R564 VanDerWaalsContact C-N 3.31Å; S562-R564 PolarHBondContact O-N 3.06Å; R564-T566 VanDerWaalsContact C-N 3.29Å; R564-T566 PolarHBondContact O-N 3.42Å
565G75.2Confident90.1Very high71 Ų7147.5 Ų47.573%0.73224%0.242SC*.THydrogen-bonded Turntrans-77.9-1017700000114.1S562 A563S562-G565 PolarHBondContact O-N 3.48Å; A563-G565 PolarHBondContact O-N 3.25Å
566T75.3Confident90.1Very high50 Ų5046.5 Ų46.531%0.30724%0.237SC..SBendtrans-133.9119.8179.2-41.10000111A563 R564 H568 R569A563-T566 CarbonylContact O-C 3.45Å; A563-T566 PolarHBondContact O-N 2.79Å; R564-T566 VanDerWaalsContact C-N 3.29Å; R564-T566 PolarHBondContact O-N 3.42Å; T566-H568 PolarHBondContact O-N 3.05Å; T566-R569 VanDerWaalsContact CB-CZ 3.49Å; T566-R569 VanDerWaalsContact CG2-CZ 3.48Å; T566-R569 PolarHBondContact OG1-NH1 3Å
567K75.5Confident90.1Very high171 Ų17146.5 Ų46.574%0.74324%0.237SC*.SBendtrans-56.7136.7178.7-65.9-172.3177.3-176.80110.9
568H88Confident90.2Very high56 Ų5646.5 Ų46.526%0.25924%0.242SC..SBendtrans5671.6170.2-58.6179.8000113.9T566 M619 Q624 Q654 F655 S656T566-H568 PolarHBondContact O-N 3.05Å; H568-M619 HydrophobicContact CB-CE 4.48Å; H568-M619 HydrophobicContact CB-SD 3.54Å; H568-M619 VanDerWaalsContact CB-SD 3.54Å; H568-Q624 VanDerWaalsContact CA-O 3.28Å; H568-Q624 WeakPolarHBondContact CA-O 3.5Å; H568-Q624 PolarHBondContact N-O 3.27Å; H568-Q654 WeakPolarHBondContact CB-O 3.37Å; H568-Q654 PolarHBondContact ND1-O 2.98Å; H568-F655 HydrophobicContact CB-CB 4.11Å; H568-F655 VanDerWaalsContact O-CA 3.31Å; H568-F655 WeakPolarHBondContact O-CA 3.41Å; H568-F655 WeakPolarHBondContact O-CB 3.28Å; H568-S656 PolarHBondContact O-N 3.32Å
569R91.9Very high90.4Very high42 Ų4244.5 Ų44.516%0.15823%0.231CC..EExtended strand (participates in β ladder)trans-120.5132.9-179.9-174.3157.1-72.1165.71.7113.7A563 T566 F571 Q624 R625 Y626 S656A563-R569 HydrophobicContact CB-CB 4.5Å; T566-R569 VanDerWaalsContact CB-CZ 3.49Å; T566-R569 VanDerWaalsContact CG2-CZ 3.48Å; T566-R569 PolarHBondContact OG1-NH1 3Å; R569-F571 HydrophobicContact CG-CD2 4.16Å; R569-F571 HydrophobicContact CG-CE2 3.75Å; R569-F571 HydrophobicContact CG-CZ 4.11Å; R569-Q624 PolarHBondContact N-O 2.94Å; R569-Q624 VanDerWaalsContact N-O 3.14Å; R569-R625 CarbonylContact O-C 3.58Å; R569-R625 VanDerWaalsContact O-CA 3.25Å; R569-R625 WeakPolarHBondContact O-CA 3.22Å; R569-Y626 PolarHBondContact O-N 3.4Å; R569-S656 WeakPolarHBondContact CA-O 3.26Å; R569-S656 PolarHBondContact NE-OG 3.02Å; R569-S656 VanDerWaalsContact NE-OG 3.16Å
570V94.1Very high90.6Very high0 Ų043.5 Ų43.50%023%0.226CC..EExtended strand (participates in β ladder)trans-105.5132.7173.7-173.30000109.9I615 M619 Y626 F647 F655 S656 T657 R658V570-I615 HydrophobicContact CG1-CD1 4.27Å; V570-I615 HydrophobicContact CG2-CD1 4.38Å; V570-I615 HydrophobicContact CG2-CG2 3.67Å; V570-M619 HydrophobicContact CG2-CE 3.82Å; V570-Y626 CarbonylContact C-O 3.5Å; V570-Y626 VanDerWaalsContact CA-O 3.29Å; V570-Y626 WeakPolarHBondContact CA-O 3.46Å; V570-Y626 HydrophobicContact CG1-CD1 4.21Å; V570-F647 HydrophobicContact CG1-CD2 3.88Å; V570-F647 HydrophobicContact CG1-CE2 4.07Å; V570-F655 HydrophobicContact CB-CD2 4.3Å; V570-F655 HydrophobicContact CG2-CB 4.22Å; V570-F655 HydrophobicContact CG2-CD2 3.31Å; V570-F655 HydrophobicContact CG2-CE2 3.7Å; V570-F655 HydrophobicContact CG2-CG 3.81Å; V570-F655 HydrophobicContact CG2-CZ 4.48Å; V570-S656 PolarHBondContact N-O 2.91Å; V570-T657 HydrophobicContact CB-CG2 4.3Å; V570-T657 HydrophobicContact CG1-CG2 4.35Å; V570-T657 CarbonylContact O-C 3.52Å; V570-T657 WeakPolarHBondContact O-CA 3.23Å; V570-R658 PolarHBondContact O-N 3.31Å
571F95.9Very high91Very high9 Ų943.4 Ų43.44%0.03923%0.226CC..EExtended strand (participates in β ladder)trans-115.8129.1171.1-76.2-75.9000110.9L559 A563 R569 V573 Y626 I627 V628 R658 N660L559-F571 HydrophobicContact CB-CD2 4.3Å; L559-F571 HydrophobicContact CB-CE2 4.41Å; L559-F571 HydrophobicContact CB-CG 4.41Å; L559-F571 HydrophobicContact CD1-CD1 4.49Å; L559-F571 HydrophobicContact CD2-CD1 4.28Å; L559-F571 HydrophobicContact CD2-CE1 4.02Å; L559-F571 HydrophobicContact CD2-CZ 4.36Å; L559-F571 WeakPolarHBondContact O-CE2 3.37Å; A563-F571 HydrophobicContact CB-CD2 4.36Å; A563-F571 HydrophobicContact CB-CE2 3.87Å; R569-F571 HydrophobicContact CG-CD2 4.16Å; R569-F571 HydrophobicContact CG-CE2 3.75Å; R569-F571 HydrophobicContact CG-CZ 4.11Å; F571-V573 HydrophobicContact CB-CG2 4.4Å; F571-Y626 PolarHBondContact N-O 3.14Å; F571-I627 HydrophobicContact CB-CG1 4.43Å; F571-V628 PolarHBondContact O-N 3.48Å; F571-R658 CarbonylContact C-O 3.48Å; F571-R658 WeakPolarHBondContact CA-O 3.29Å; F571-R658 HydrophobicContact CD1-CB 3.7Å; F571-R658 HydrophobicContact CE1-CB 3.6Å; F571-R658 HydrophobicContact CE1-CG 4.3Å; F571-N660 WeakPolarHBondContact CD1-ND2 3.43Å
572I97.3Very high91.4Very high0 Ų036.7 Ų36.70%019%0.194CC..EExtended strand (participates in β ladder)trans-103.3114.3166.5-52.8174.8000107.2V628 R630 T640 M643 F647 T657 R658 I659 N660I572-V628 HydrophobicContact CG1-CB 4.43Å; I572-V628 HydrophobicContact CG2-CG1 4.3Å; I572-R630 HydrophobicContact CG2-CB 4.29Å; I572-T640 HydrophobicContact CG2-CG2 4.05Å; I572-M643 HydrophobicContact CD1-CB 3.75Å; I572-F647 HydrophobicContact CD1-CD2 3.94Å; I572-F647 HydrophobicContact CD1-CE2 4.19Å; I572-F647 HydrophobicContact CD1-CG 4.48Å; I572-F647 HydrophobicContact CG1-CD2 4.3Å; I572-F647 HydrophobicContact CG1-CE2 4.32Å; I572-T657 HydrophobicContact CD1-CG2 4.02Å; I572-T657 HydrophobicContact CG1-CG2 4.21Å; I572-R658 PolarHBondContact N-O 3.32Å; I572-I659 HydrophobicContact CB-CG2 4.28Å; I572-I659 CarbonylContact O-C 3.54Å; I572-I659 VanDerWaalsContact O-CA 3.31Å; I572-I659 WeakPolarHBondContact O-CA 3.44Å; I572-N660 PolarHBondContact O-N 3.02Å
573V98Very high91.9Very high0 Ų033.7 Ų33.70%017%0.173CC..EExtended strand (participates in β ladder)trans-106.1109.5-176-175.70000108.5V556 L559 F571 I627 V628 T629 R630 N660 L662V556-V573 HydrophobicContact CG2-CG1 4.26Å; V556-V573 HydrophobicContact CG2-CG2 4.43Å; L559-V573 HydrophobicContact CD1-CG2 3.55Å; F571-V573 HydrophobicContact CB-CG2 4.4Å; V573-I627 HydrophobicContact CG2-CG2 4.32Å; V573-V628 PolarHBondContact N-O 3.06Å; V573-T629 CarbonylContact O-C 3.56Å; V573-T629 WeakPolarHBondContact O-CA 3.48Å; V573-R630 PolarHBondContact O-N 2.82Å; V573-N660 CarbonylContact C-O 3.58Å; V573-N660 WeakPolarHBondContact CA-O 3.33Å; V573-L662 HydrophobicContact CG1-CD1 3.72Å; V573-L662 HydrophobicContact CG1-CD2 3.83Å; V573-L662 HydrophobicContact CG1-CG 3.75Å
574E98.5Very high92.5Very high38 Ų3833.7 Ų33.718%0.17817%0.173CC..EExtended strand (participates in β ladder)trans-82.8119.6177.2-170.9-179.7104.300110.2R630 E632 T640 N660 V661 L662E574-R630 CarbonylContact C-O 3.59Å; E574-R630 VanDerWaalsContact CA-O 3.27Å; E574-R630 WeakPolarHBondContact CA-O 3.41Å; E574-R630 IonicContact OE2-NH1 2.75Å; E574-R630 PolarHBondContact OE2-NH1 3.37Å; E574-E632 HydrophobicContact CG-CB 4.27Å; E574-T640 HydrophobicContact CB-CG2 4.49Å; E574-T640 VanDerWaalsContact OE2-CB 3.28Å; E574-T640 WeakPolarHBondContact OE2-CB 3.33Å; E574-T640 PolarHBondContact OE2-OG1 3.44Å; E574-N660 PolarHBondContact N-O 3.49Å; E574-V661 HydrophobicContact CB-CB 4.45Å; E574-V661 HydrophobicContact CB-CG1 4.45Å; E574-V661 HydrophobicContact CB-CG2 4.1Å; E574-V661 WeakPolarHBondContact OE1-CG1 3.47Å; E574-L662 PolarHBondContact O-N 3.45Å
575T98.4Very high93.5Very high2 Ų227.7 Ų27.71%0.01215%0.15CC..EExtended strand (participates in β ladder)trans-100.4151.6174.667.10000110.2I552 A584 R630 E632 Q666I552-T575 HydrophobicContact CD1-CG2 4.18Å; I552-T575 HydrophobicContact CG2-CG2 4.05Å; T575-A584 WeakPolarHBondContact OG1-CB 3.41Å; T575-A584 PolarHBondContact OG1-N 3.49Å; T575-R630 PolarHBondContact N-O 2.9Å; T575-R630 PolarHBondContact OG1-O 3.46Å; T575-E632 PolarHBondContact O-N 2.99Å; T575-Q666 VanDerWaalsContact CA-OE1 3.26Å
576M98Very high94.6Very high30 Ų3024.4 Ų24.415%0.14812%0.116CC..  trans-69.1175166.2-76.5173.686.700109.8I532 G663 Q666I532-M576 HydrophobicContact CD1-CB 4.15Å; I532-M576 HydrophobicContact CD1-CE 4.35Å; I532-M576 HydrophobicContact CD1-SD 4.01Å; M576-G663 VanDerWaalsContact SD-O 3.37Å; M576-Q666 VanDerWaalsContact CG-NE2 3.26Å; M576-Q666 HydrophobicContact SD-CB 4.47Å
577G96.5Very high95.7Very high0 Ų022 Ų220%010%0.101CC..  trans150.4-6.2176.500000113.2Y579 C580 E632G577-Y579 PolarHBondContact O-N 3.01Å; G577-C580 VanDerWaalsContact O-CB 3.27Å; G577-C580 WeakPolarHBondContact O-CB 3.41Å; G577-C580 PolarHBondContact O-N 3.45Å; G577-E632 PolarHBondContact N-OE1 2.78Å
578G96.7Very high96.7Very high21 Ų2113.9 Ų13.922%0.2167%0.066CC..THydrogen-bonded Turntrans58-124.3-162.900000109C580 C631 E632 N633G578-C580 VanDerWaalsContact C-N 3.34Å; G578-C631 PolarHBondContact O-SG 3.43Å; G578-E632 WeakPolarHBondContact CA-OE1 3.42Å; G578-E632 PolarHBondContact N-OE1 2.79Å; G578-N633 VanDerWaalsContact O-CB 3.26Å; G578-N633 WeakPolarHBondContact O-CB 3.44Å; G578-N633 PolarHBondContact O-N 2.87Å
579Y97.4Very high97.1Very high85 Ų8511.4 Ų11.433%0.3335%0.054SC..THydrogen-bonded Turntrans-86.5-1.8173.2-65.3-81.6000113.4G577 F599 N633 H738G577-Y579 PolarHBondContact O-N 3.01Å; Y579-F599 HydrophobicContact CD1-CB 4.47Å; Y579-F599 HydrophobicContact CD1-CD1 4.19Å; Y579-F599 AromaticContact CD1-CD2 3.6Å; Y579-F599 HydrophobicContact CD1-CD2 3.6Å; Y579-F599 HydrophobicContact CD1-CE1 4.32Å; Y579-F599 AromaticContact CD1-CE2 3.75Å; Y579-F599 HydrophobicContact CD1-CE2 3.75Å; Y579-F599 AromaticContact CD1-CG 3.83Å; Y579-F599 HydrophobicContact CD1-CG 3.83Å; Y579-F599 HydrophobicContact CD1-CZ 4.11Å; Y579-F599 HydrophobicContact CE1-CD2 4.22Å; Y579-F599 HydrophobicContact CE1-CE2 4.11Å; Y579-F599 HydrophobicContact CG-CG 4.49Å; Y579-F599 VanDerWaalsContact O-CB 3.31Å; Y579-F599 WeakPolarHBondContact O-CB 3.44Å; Y579-N633 HydrophobicContact CD1-CB 3.59Å; Y579-N633 HydrophobicContact CE1-CB 3.65Å; Y579-N633 HydrophobicContact CG-CB 4.07Å; Y579-H738 HydrophobicContact CD2-CB 3.98Å; Y579-H738 WeakPolarHBondContact CD2-O 3.43Å; Y579-H738 AromaticContact CE1-CD2 3.96Å; Y579-H738 HydrophobicContact CG-CB 3.98Å
580C97.8Very high97.3Very high0 Ų09.4 Ų9.40%05%0.047CC..  trans-88.8115-178.4-173.20000110.7S533 N535 G577 G578 Y582 E600 C631 L740S533-C580 PolarHBondContact O-SG 3.29Å; N535-C580 HydrophobicContact CB-CB 3.78Å; G577-C580 VanDerWaalsContact O-CB 3.27Å; G577-C580 WeakPolarHBondContact O-CB 3.41Å; G577-C580 PolarHBondContact O-N 3.45Å; G578-C580 VanDerWaalsContact C-N 3.34Å; C580-Y582 PolarHBondContact O-N 3.15Å; C580-Y582 VanDerWaalsContact SG-CB 3.56Å; C580-E600 WeakPolarHBondContact CA-OE1 3.44Å; C580-C631 PolarHBondContact O-SG 3.5Å; C580-L740 HydrophobicContact CB-CD2 3.56Å
581G97.7Very high97.4Very high0 Ų09.4 Ų9.40%05%0.047CC..THydrogen-bonded Turntrans-74.64.5178.700000115.6L583 A584 T585 E600G581-L583 PolarHBondContact O-N 3.11Å; G581-A584 PolarHBondContact O-N 3.5Å; G581-T585 WeakPolarHBondContact O-CB 3.35Å; G581-T585 PolarHBondContact O-N 3.12Å; G581-T585 PolarHBondContact O-OG1 2.56Å; G581-E600 WeakPolarHBondContact CA-OE2 3.12Å; G581-E600 PolarHBondContact N-OE1 3.48Å; G581-E600 PolarHBondContact N-OE2 3.01Å
582Y98Very high97.3Very high6 Ų69.4 Ų9.42%0.0245%0.049CC..Hα-helixtrans-52.9-53.6-175.4175-93.5000112.5N534 L549 C580 T585 L586 W745 W746N534-Y582 HydrophobicContact CB-CD1 3.6Å; N534-Y582 HydrophobicContact CB-CD2 3.98Å; N534-Y582 HydrophobicContact CB-CE1 3.83Å; N534-Y582 HydrophobicContact CB-CE2 4.15Å; N534-Y582 HydrophobicContact CB-CG 3.7Å; N534-Y582 WeakPolarHBondContact ND2-CD2 3.36Å; N534-Y582 WeakPolarHBondContact ND2-CE2 3.46Å; L549-Y582 HydrophobicContact CD1-CE1 3.97Å; L549-Y582 HydrophobicContact CG-CE1 4.38Å; C580-Y582 PolarHBondContact O-N 3.15Å; C580-Y582 VanDerWaalsContact SG-CB 3.56Å; Y582-T585 PolarHBondContact O-N 3.33Å; Y582-L586 HydrophobicContact CD1-CD1 4.13Å; Y582-L586 HydrophobicContact CD2-CD1 3.46Å; Y582-L586 VanDerWaalsContact CD2-CD1 3.46Å; Y582-L586 HydrophobicContact CE1-CD1 3.71Å; Y582-L586 HydrophobicContact CE2-CD1 3Å; Y582-L586 HydrophobicContact CE2-CG 4.35Å; Y582-L586 HydrophobicContact CG-CD1 4.02Å; Y582-L586 WeakPolarHBondContact O-CB 3.42Å; Y582-L586 PolarHBondContact O-N 2.84Å; Y582-L586 WeakPolarHBondContact OH-CD1 3.44Å; Y582-W745 AromaticContact CE2-CZ2 3.98Å; Y582-W745 HydrophobicContact CE2-CZ2 3.98Å; Y582-W746 HydrophobicContact CD2-CB 4.18Å; Y582-W746 AromaticContact CD2-CD1 3.5Å; Y582-W746 VanDerWaalsContact CD2-CD1 3.5Å; Y582-W746 HydrophobicContact CD2-CD2 4.18Å; Y582-W746 AromaticContact CD2-CG 3.68Å; Y582-W746 HydrophobicContact CD2-CG 3.68Å; Y582-W746 AromaticContact CD2-NE1 3.83Å; Y582-W746 HydrophobicContact CE2-CG 4.45Å; Y582-W746 VanDerWaalsContact N-CH2 3.3Å; Y582-W746 VanDerWaalsContact N-CZ2 3.32Å
583L98.2Very high97.1Very high0 Ų09.5 Ų9.50%05%0.05CC..Hα-helixtrans-65-45.9-177.9-70.6179.4000111.5I532 A548 L549 I552 G581 T585 A587I532-L583 HydrophobicContact CB-CD1 4.35Å; I532-L583 HydrophobicContact CD1-CD1 4.38Å; I532-L583 HydrophobicContact CG1-CD1 4.28Å; I532-L583 WeakPolarHBondContact O-CD1 3.42Å; I532-L583 WeakPolarHBondContact O-CD2 3.38Å; I532-L583 WeakPolarHBondContact O-CG 3.21Å; A548-L583 HydrophobicContact CB-CD1 4.47Å; A548-L583 HydrophobicContact CB-CD2 3.93Å; L549-L583 HydrophobicContact CD2-CD2 3.82Å; L549-L583 HydrophobicContact CG-CD2 4.01Å; I552-L583 HydrophobicContact CD1-CB 3.93Å; I552-L583 HydrophobicContact CD1-CD1 4.27Å; I552-L583 HydrophobicContact CD1-CD2 4.05Å; I552-L583 HydrophobicContact CD1-CG 4.31Å; G581-L583 PolarHBondContact O-N 3.11Å; L583-T585 VanDerWaalsContact C-N 3.34Å; L583-T585 PolarHBondContact O-N 3.17Å; L583-A587 WeakPolarHBondContact O-CB 3.27Å; L583-A587 PolarHBondContact O-N 2.99Å
584A97.9Very high96.8Very high0 Ų010.3 Ų10.30%06%0.055CC..Hα-helixtrans-59.1-45.8178.300000111.6T575 G581 G588 I598 T629 C631T575-A584 WeakPolarHBondContact OG1-CB 3.41Å; T575-A584 PolarHBondContact OG1-N 3.49Å; G581-A584 PolarHBondContact O-N 3.5Å; A584-G588 WeakPolarHBondContact O-CA 3.32Å; A584-G588 PolarHBondContact O-N 2.8Å; A584-I598 HydrophobicContact CB-CG2 3.91Å; A584-T629 WeakPolarHBondContact O-CB 3.34Å; A584-T629 PolarHBondContact O-OG1 3.02Å; A584-C631 HydrophobicContact CB-CB 4.07Å
585T97.8Very high96.6Very high0 Ų08.7 Ų8.70%05%0.047CC..Hα-helixtrans-70.4-52.9-176.6-56.90000111.5G581 Y582 L583 G588 L589 W746 H750 L753G581-T585 WeakPolarHBondContact O-CB 3.35Å; G581-T585 PolarHBondContact O-N 3.12Å; G581-T585 PolarHBondContact O-OG1 2.56Å; Y582-T585 PolarHBondContact O-N 3.33Å; L583-T585 VanDerWaalsContact C-N 3.34Å; L583-T585 PolarHBondContact O-N 3.17Å; T585-G588 PolarHBondContact O-N 3.3Å; T585-L589 PolarHBondContact O-N 3.14Å; T585-W746 HydrophobicContact CG2-CE3 4.22Å; T585-W746 HydrophobicContact CG2-CZ3 4.43Å; T585-W746 WeakPolarHBondContact OG1-CZ3 3.38Å; T585-H750 HydrophobicContact CG2-CB 4.05Å; T585-L753 WeakPolarHBondContact O-CD1 3.32Å
586L97.7Very high96.5Very high3 Ų38.7 Ų8.72%0.0165%0.047CC..Hα-helixtrans-72-41.5-175.5-75.9171.6000112.4L306 L549 Y582 G588 L589 A590 L749L306-L586 HydrophobicContact CD1-CB 4.24Å; L306-L586 HydrophobicContact CD1-CD2 3.98Å; L306-L586 HydrophobicContact CD2-CB 4.42Å; L306-L586 HydrophobicContact CD2-CD2 3.68Å; L306-L586 HydrophobicContact CG-CD2 4.46Å; L549-L586 HydrophobicContact CD1-CB 4.24Å; L549-L586 HydrophobicContact CD1-CD1 4.23Å; L549-L586 HydrophobicContact CD2-CB 3.71Å; Y582-L586 HydrophobicContact CD1-CD1 4.13Å; Y582-L586 HydrophobicContact CD2-CD1 3.46Å; Y582-L586 VanDerWaalsContact CD2-CD1 3.46Å; Y582-L586 HydrophobicContact CE1-CD1 3.71Å; Y582-L586 HydrophobicContact CE2-CD1 3Å; Y582-L586 HydrophobicContact CE2-CG 4.35Å; Y582-L586 HydrophobicContact CG-CD1 4.02Å; Y582-L586 WeakPolarHBondContact O-CB 3.42Å; Y582-L586 PolarHBondContact O-N 2.84Å; Y582-L586 WeakPolarHBondContact OH-CD1 3.44Å; L586-G588 VanDerWaalsContact C-N 3.25Å; L586-G588 PolarHBondContact O-N 2.85Å; L586-L589 PolarHBondContact O-N 2.73Å; L586-A590 VanDerWaalsContact O-CB 3.27Å; L586-A590 WeakPolarHBondContact O-CB 3.3Å; L586-A590 PolarHBondContact O-N 2.78Å; L586-L749 HydrophobicContact CD2-CD1 3.54Å
587A97.6Very high96.5Very high0 Ų07.6 Ų7.60%04%0.042CC..Hα-helixtrans-66-34.7174.500000111L549 I552 L583 S591L549-A587 HydrophobicContact CD2-CB 3.95Å; I552-A587 HydrophobicContact CB-CB 3.82Å; I552-A587 HydrophobicContact CD1-CB 4.24Å; I552-A587 HydrophobicContact CG2-CB 3.36Å; L583-A587 WeakPolarHBondContact O-CB 3.27Å; L583-A587 PolarHBondContact O-N 2.99Å; A587-S591 WeakPolarHBondContact O-CB 3.33Å; A587-S591 PolarHBondContact O-N 3.36Å; A587-S591 PolarHBondContact O-OG 3.05Å
588G96.6Very high96.5Very high0 Ų07.7 Ų7.70%04%0.042CC..Hα-helixtrans-58.2-48.9171.100000111.8A584 T585 L586 S591 G592 A593A584-G588 WeakPolarHBondContact O-CA 3.32Å; A584-G588 PolarHBondContact O-N 2.8Å; T585-G588 PolarHBondContact O-N 3.3Å; L586-G588 VanDerWaalsContact C-N 3.25Å; L586-G588 PolarHBondContact O-N 2.85Å; G588-S591 PolarHBondContact O-N 3.5Å; G588-G592 PolarHBondContact O-N 2.89Å; G588-A593 WeakPolarHBondContact O-CB 3.28Å; G588-A593 PolarHBondContact O-N 2.9Å
589L97Very high96.6Very high3 Ų39.8 Ų9.82%0.0165%0.046CC..Hα-helixtrans-64.6-49.3178.9177.959.3000111.5L306 T585 L586 S591 G592 L749 L752 L753 L756L306-L589 HydrophobicContact CD2-CB 3.97Å; L306-L589 HydrophobicContact CD2-CD2 3.73Å; L306-L589 HydrophobicContact CD2-CG 3.83Å; T585-L589 PolarHBondContact O-N 3.14Å; L586-L589 PolarHBondContact O-N 2.73Å; L589-S591 PolarHBondContact O-N 2.76Å; L589-G592 PolarHBondContact O-N 3.47Å; L589-G592 VanDerWaalsContact O-N 3.12Å; L589-L749 HydrophobicContact CD2-CB 4.28Å; L589-L752 HydrophobicContact CD1-CD2 4.46Å; L589-L752 HydrophobicContact CD1-CG 4.26Å; L589-L752 HydrophobicContact CD2-CD2 4.23Å; L589-L753 HydrophobicContact CB-CB 4.41Å; L589-L753 HydrophobicContact CB-CD1 4.31Å; L589-L753 HydrophobicContact CD1-CB 4.35Å; L589-L756 HydrophobicContact CD1-CD1 3.7Å
590A97.3Very high96.5Very high0 Ų08 Ų80%04%0.04CC..Hα-helixtrans-66.8-26.3-178.900000112.8I72 R305 L306 L586I72-A590 VanDerWaalsContact CD1-O 3.31Å; I72-A590 WeakPolarHBondContact CD1-O 3.42Å; R305-A590 HydrophobicContact CB-CB 4.12Å; R305-A590 WeakPolarHBondContact CD-O 3.41Å; L306-A590 HydrophobicContact CD1-CB 4.36Å; L306-A590 HydrophobicContact CD2-CB 3.88Å; L306-A590 HydrophobicContact CG-CB 3.74Å; L586-A590 VanDerWaalsContact O-CB 3.27Å; L586-A590 WeakPolarHBondContact O-CB 3.3Å; L586-A590 PolarHBondContact O-N 2.78Å
591S95.4Very high96.3Very high0 Ų011.7 Ų11.70%06%0.057CC..Hα-helixtrans-94.1-5.6175.9-54.20000112.7C553 K560 A587 G588 L589 A593C553-S591 WeakPolarHBondContact CA-OG 3.31Å; C553-S591 PolarHBondContact SG-OG 2.91Å; K560-S591 WeakPolarHBondContact CE-O 3.33Å; K560-S591 PolarHBondContact NZ-O 2.99Å; A587-S591 WeakPolarHBondContact O-CB 3.33Å; A587-S591 PolarHBondContact O-N 3.36Å; A587-S591 PolarHBondContact O-OG 3.05Å; G588-S591 PolarHBondContact O-N 3.5Å; L589-S591 PolarHBondContact O-N 2.76Å; S591-A593 VanDerWaalsContact C-N 3.29Å; S591-A593 PolarHBondContact O-N 3.1Å
592G93.2Very high96Very high9 Ų918 Ų189%0.09310%0.096CC..THydrogen-bonded Turntrans58.643.6-171.600000112.2G588 L589G588-G592 PolarHBondContact O-N 2.89Å; L589-G592 PolarHBondContact O-N 3.47Å; L589-G592 VanDerWaalsContact O-N 3.12Å
593A93.9Very high95.8Very high3 Ų318.9 Ų18.93%0.02510%0.1CC..  trans-65.1156.2162.100000109.7G588 S591 I627 T629G588-A593 WeakPolarHBondContact O-CB 3.28Å; G588-A593 PolarHBondContact O-N 2.9Å; S591-A593 VanDerWaalsContact C-N 3.29Å; S591-A593 PolarHBondContact O-N 3.1Å; A593-I627 HydrophobicContact CB-CB 4.31Å; A593-I627 HydrophobicContact CB-CG2 3.95Å; A593-T629 HydrophobicContact CB-CG2 4.27Å
594D92.3Very high95.6Very high16 Ų1620 Ų209%0.08611%0.111CC..SBendtrans-88.6-28.3-175.5-66.8-89.5000112.9K618 Y626 I627 A757 Y759D594-K618 IonicContact OD1-NZ 2.93Å; D594-K618 PolarHBondContact OD1-NZ 3.45Å; D594-Y626 HydrophobicContact CB-CD1 3.92Å; D594-Y626 HydrophobicContact CB-CD2 3.69Å; D594-Y626 HydrophobicContact CB-CE1 3.53Å; D594-Y626 HydrophobicContact CB-CE2 3.3Å; D594-Y626 HydrophobicContact CB-CG 3.98Å; D594-Y626 WeakPolarHBondContact OD2-CA 3.31Å; D594-I627 PolarHBondContact N-O 2.84Å; D594-I627 PolarHBondContact OD2-N 3.32Å; D594-A757 HydrophobicContact CB-CB 4.46Å; D594-A757 WeakPolarHBondContact O-CB 3.3Å; D594-Y759 WeakPolarHBondContact O-CE2 3.36Å
595N94.2Very high95.4Very high4 Ų422.6 Ų22.62%0.02113%0.127CC..EExtended strand (participates in β ladder)trans-151.9160.1174.4-159.17.2000111.4D611 I627 V628 T629N595-D611 PolarHBondContact ND2-OD2 2.82Å; N595-I627 PolarHBondContact N-O 3.48Å; N595-V628 WeakPolarHBondContact O-CA 3.46Å; N595-T629 PolarHBondContact O-N 3.41Å; N595-T629 PolarHBondContact O-OG1 2.93Å
596A96.4Very high95.2Very high2 Ų227.6 Ų27.62%0.01715%0.154CC..EExtended strand (participates in β ladder)trans-133.1118.6173.900000110.5T629 H750 L753A596-T629 CarbonylContact C-O 3.3Å; A596-T629 VanDerWaalsContact CA-O 3.23Å; A596-T629 WeakPolarHBondContact CA-O 3.44Å; A596-T629 VanDerWaalsContact CB-OG1 3.31Å; A596-T629 WeakPolarHBondContact CB-OG1 3.41Å; A596-H750 PolarHBondContact O-NE2 3.37Å; A596-L753 HydrophobicContact CB-CD1 3.97Å
597Y97.2Very high95Very high7 Ų731.2 Ų31.23%0.02717%0.173CC..EExtended strand (participates in β ladder)trans-90.8123.8171.8-63-79.4000110.1F603 I608 D611 V628 T629 R630 C631 M643Y597-F603 HydrophobicContact CD1-CB 4.5Å; Y597-F603 AromaticContact CD1-CD1 3.99Å; Y597-F603 HydrophobicContact CD1-CD1 3.99Å; Y597-F603 AromaticContact CD1-CD2 3.71Å; Y597-F603 HydrophobicContact CD1-CD2 3.71Å; Y597-F603 HydrophobicContact CD1-CE1 4.11Å; Y597-F603 AromaticContact CD1-CE2 3.8Å; Y597-F603 HydrophobicContact CD1-CE2 3.8Å; Y597-F603 AromaticContact CD1-CG 3.81Å; Y597-F603 HydrophobicContact CD1-CG 3.81Å; Y597-F603 HydrophobicContact CD1-CZ 4.01Å; Y597-F603 HydrophobicContact CE1-CD2 4.03Å; Y597-F603 HydrophobicContact CE1-CE2 4.37Å; Y597-F603 HydrophobicContact CE1-CG 4.31Å; Y597-F603 HydrophobicContact CG-CE2 4.39Å; Y597-F603 HydrophobicContact CG-CZ 4.31Å; Y597-I608 HydrophobicContact CE1-CG1 4.22Å; Y597-D611 VanDerWaalsContact CZ-OD2 3.3Å; Y597-D611 PolarHBondContact OH-OD2 3.2Å; Y597-V628 HydrophobicContact CD2-CG1 3.3Å; Y597-V628 HydrophobicContact CE2-CB 4.48Å; Y597-V628 HydrophobicContact CE2-CG1 3.36Å; Y597-V628 HydrophobicContact CE2-CG2 4.29Å; Y597-T629 PolarHBondContact N-O 3.35Å; Y597-R630 WeakPolarHBondContact O-CA 3.46Å; Y597-C631 PolarHBondContact O-N 3.42Å; Y597-M643 HydrophobicContact CD1-CE 4.18Å; Y597-M643 HydrophobicContact CD2-CE 3.39Å; Y597-M643 HydrophobicContact CD2-SD 4.29Å; Y597-M643 HydrophobicContact CE1-CE 3.94Å; Y597-M643 HydrophobicContact CE2-CE 3.08Å; Y597-M643 HydrophobicContact CE2-SD 4.48Å; Y597-M643 HydrophobicContact CG-CE 3.93Å
598I97.2Very high94.8Very high2 Ų231.2 Ų31.21%0.0117%0.173CC..  trans-135.7162.8-174.862173.1000110.1A584 E600 Q601 W746 L747A584-I598 HydrophobicContact CB-CG2 3.91Å; I598-E600 WeakPolarHBondContact CB-OE2 3.45Å; I598-E600 HydrophobicContact CD1-CB 4.2Å; I598-Q601 HydrophobicContact CD1-CB 4.23Å; I598-Q601 HydrophobicContact CG1-CB 3.85Å; I598-W746 HydrophobicContact CD1-CH2 4.26Å; I598-W746 HydrophobicContact CD1-CZ3 3.95Å; I598-L747 HydrophobicContact CD1-CD2 3.88Å
599F97.1Very high94.6Very high66 Ų6634.6 Ų34.629%0.28919%0.188SC..SBendtrans-73.6-36.7-178.1171.6-104.9000111.6Y579 Q601 H738 L740Y579-F599 HydrophobicContact CD1-CB 4.47Å; Y579-F599 HydrophobicContact CD1-CD1 4.19Å; Y579-F599 AromaticContact CD1-CD2 3.6Å; Y579-F599 HydrophobicContact CD1-CD2 3.6Å; Y579-F599 HydrophobicContact CD1-CE1 4.32Å; Y579-F599 AromaticContact CD1-CE2 3.75Å; Y579-F599 HydrophobicContact CD1-CE2 3.75Å; Y579-F599 AromaticContact CD1-CG 3.83Å; Y579-F599 HydrophobicContact CD1-CG 3.83Å; Y579-F599 HydrophobicContact CD1-CZ 4.11Å; Y579-F599 HydrophobicContact CE1-CD2 4.22Å; Y579-F599 HydrophobicContact CE1-CE2 4.11Å; Y579-F599 HydrophobicContact CG-CG 4.49Å; Y579-F599 VanDerWaalsContact O-CB 3.31Å; Y579-F599 WeakPolarHBondContact O-CB 3.44Å; F599-Q601 PolarHBondContact O-N 3.29Å; F599-H738 HydrophobicContact CE1-CB 4.32Å; F599-H738 AromaticContact CZ-CD2 3.59Å; F599-H738 AromaticContact CZ-CG 3.87Å; F599-H738 AromaticContact CZ-NE2 3.73Å; F599-L740 HydrophobicContact CD1-CD1 3.84Å; F599-L740 HydrophobicContact CE1-CD1 3.92Å
600E96Very high94.4Very high46 Ų4638.4 Ų38.422%0.21521%0.208CC..SBendtrans-66.3-21-176.5-60.385.8163.400113.2C580 G581 I598 Q744 W746 L747C580-E600 WeakPolarHBondContact CA-OE1 3.44Å; G581-E600 WeakPolarHBondContact CA-OE2 3.12Å; G581-E600 PolarHBondContact N-OE1 3.48Å; G581-E600 PolarHBondContact N-OE2 3.01Å; I598-E600 WeakPolarHBondContact CB-OE2 3.45Å; I598-E600 HydrophobicContact CD1-CB 4.2Å; E600-Q744 VanDerWaalsContact CG-NE2 3.33Å; E600-Q744 PolarHBondContact OE1-OE1 3.13Å; E600-W746 VanDerWaalsContact CD-CH2 3.45Å; E600-W746 HydrophobicContact CG-CH2 4.19Å; E600-W746 VanDerWaalsContact OE1-CH2 3.22Å; E600-W746 WeakPolarHBondContact OE1-CH2 3.42Å; E600-W746 VanDerWaalsContact OE1-CZ2 3.26Å; E600-W746 WeakPolarHBondContact OE1-CZ2 3.43Å; E600-L747 HydrophobicContact CB-CD1 4.28Å; E600-L747 HydrophobicContact CB-CD2 3.57Å; E600-L747 HydrophobicContact CG-CD1 4.46Å; E600-L747 HydrophobicContact CG-CD2 3.97Å
601Q93.2Very high94.2Very high78 Ų7838.8 Ų38.836%0.36421%0.21SC..SBendtrans-112.6109.7174.2-177.1172.217.800108.9I598 F599 F603 H750I598-Q601 HydrophobicContact CD1-CB 4.23Å; I598-Q601 HydrophobicContact CG1-CB 3.85Å; F599-Q601 PolarHBondContact O-N 3.29Å; Q601-F603 WeakPolarHBondContact O-CD1 3.26Å; Q601-H750 PolarHBondContact OE1-CE1 3.1Å; Q601-H750 PolarHBondContact OE1-ND1 3.34Å; Q601-H750 PolarHBondContact OE1-NE2 3.1Å
602T92.1Very high94.1Very high133 Ų13339.1 Ų39.182%0.81621%0.213SC*.  trans-63140.2175.853.20000110.9
603F94.4Very high94Very high24 Ų2444.5 Ų44.511%0.10523%0.233CC..  trans-143.4144.3175.260.9-83.7000110Y597 Q601 D607 I608 A634 N635 Y638Y597-F603 HydrophobicContact CD1-CB 4.5Å; Y597-F603 AromaticContact CD1-CD1 3.99Å; Y597-F603 HydrophobicContact CD1-CD1 3.99Å; Y597-F603 AromaticContact CD1-CD2 3.71Å; Y597-F603 HydrophobicContact CD1-CD2 3.71Å; Y597-F603 HydrophobicContact CD1-CE1 4.11Å; Y597-F603 AromaticContact CD1-CE2 3.8Å; Y597-F603 HydrophobicContact CD1-CE2 3.8Å; Y597-F603 AromaticContact CD1-CG 3.81Å; Y597-F603 HydrophobicContact CD1-CG 3.81Å; Y597-F603 HydrophobicContact CD1-CZ 4.01Å; Y597-F603 HydrophobicContact CE1-CD2 4.03Å; Y597-F603 HydrophobicContact CE1-CE2 4.37Å; Y597-F603 HydrophobicContact CE1-CG 4.31Å; Y597-F603 HydrophobicContact CG-CE2 4.39Å; Y597-F603 HydrophobicContact CG-CZ 4.31Å; Q601-F603 WeakPolarHBondContact O-CD1 3.26Å; F603-D607 WeakPolarHBondContact CA-OD2 3.42Å; F603-D607 HydrophobicContact CB-CB 4.25Å; F603-I608 HydrophobicContact CD2-CD1 3.95Å; F603-I608 HydrophobicContact CD2-CG1 3.99Å; F603-I608 HydrophobicContact CE2-CD1 4.03Å; F603-I608 HydrophobicContact CE2-CG1 4.43Å; F603-A634 HydrophobicContact CE1-CB 4.04Å; F603-A634 HydrophobicContact CZ-CB 4.14Å; F603-N635 HydrophobicContact CE1-CB 4.22Å; F603-N635 HydrophobicContact CE2-CB 4.28Å; F603-N635 HydrophobicContact CZ-CB 3.67Å; F603-Y638 HydrophobicContact CD2-CD2 4.01Å; F603-Y638 AromaticContact CE2-CD2 3.69Å; F603-Y638 HydrophobicContact CE2-CD2 3.69Å; F603-Y638 HydrophobicContact CE2-CG 4.26Å; F603-Y638 HydrophobicContact CZ-CD2 4.45Å; F603-Y638 WeakPolarHBondContact O-CE2 3.38Å
604G94.3Very high93.8Very high23 Ų2345.2 Ų45.224%0.23724%0.239CC..  trans-111.1-179.4176.700000112.9D606 D607 I608G604-D606 PolarHBondContact O-N 3.01Å; G604-D607 PolarHBondContact N-OD2 3.44Å; G604-D607 PolarHBondContact O-N 2.99Å; G604-I608 WeakPolarHBondContact O-CG1 3.39Å; G604-I608 PolarHBondContact O-N 3.37Å
605V93.5Very high93.8Very high55 Ų5544.4 Ų44.433%0.33324%0.235SC..Hα-helixtrans-61.2-32.7176.573.60000112.2I608 K609 L646V605-I608 PolarHBondContact O-N 3.22Å; V605-K609 HydrophobicContact CG2-CD 4.48Å; V605-K609 WeakPolarHBondContact O-CG 3.14Å; V605-K609 PolarHBondContact O-N 2.93Å; V605-L646 HydrophobicContact CG2-CD2 4.04Å
606D93.4Very high93.6Very high106 Ų10644.9 Ų44.957%0.56724%0.239SC*.Hα-helixtrans-68.1-37.3179.2-67.9-43.5000112.3G604 K609 N610G604-D606 PolarHBondContact O-N 3.01Å; D606-K609 PolarHBondContact O-N 2.97Å; D606-N610 WeakPolarHBondContact O-CB 3.47Å; D606-N610 PolarHBondContact O-N 3.45Å; D606-N610 PolarHBondContact O-ND2 3.49Å
607D93Very high93.2Very high78 Ų7850.5 Ų50.542%0.41727%0.265SS..Hα-helixtrans-62.8-45.3173.7-60-55.2000110.8F603 G604 K609 N610 D611F603-D607 WeakPolarHBondContact CA-OD2 3.42Å; F603-D607 HydrophobicContact CB-CB 4.25Å; G604-D607 PolarHBondContact N-OD2 3.44Å; G604-D607 PolarHBondContact O-N 2.99Å; D607-K609 VanDerWaalsContact C-N 3.31Å; D607-K609 PolarHBondContact O-N 2.74Å; D607-N610 WeakPolarHBondContact O-CB 3.44Å; D607-N610 PolarHBondContact O-N 3.32Å; D607-N610 VanDerWaalsContact O-N 3.16Å; D607-D611 PolarHBondContact O-N 2.84Å
608I94.1Very high92.6Very high0 Ų051.7 Ų51.70%027%0.271CS..Hα-helixtrans-62.6-40.5178.1-57.2169.4000110.4Y597 F603 G604 V605 D611 V612 Y638 M643 L646 F647Y597-I608 HydrophobicContact CE1-CG1 4.22Å; F603-I608 HydrophobicContact CD2-CD1 3.95Å; F603-I608 HydrophobicContact CD2-CG1 3.99Å; F603-I608 HydrophobicContact CE2-CD1 4.03Å; F603-I608 HydrophobicContact CE2-CG1 4.43Å; G604-I608 WeakPolarHBondContact O-CG1 3.39Å; G604-I608 PolarHBondContact O-N 3.37Å; V605-I608 PolarHBondContact O-N 3.22Å; I608-D611 PolarHBondContact O-N 2.93Å; I608-V612 PolarHBondContact O-N 3.14Å; I608-Y638 HydrophobicContact CD1-CD1 4.49Å; I608-Y638 HydrophobicContact CD1-CD2 4.19Å; I608-Y638 HydrophobicContact CD1-CG 4.06Å; I608-M643 HydrophobicContact CD1-CE 4.32Å; I608-M643 HydrophobicContact CD1-CG 4.48Å; I608-M643 HydrophobicContact CG1-CE 4.26Å; I608-M643 HydrophobicContact CG2-CE 4.19Å; I608-L646 HydrophobicContact CB-CD2 4.11Å; I608-L646 HydrophobicContact CG2-CD2 3.57Å; I608-F647 HydrophobicContact CG2-CD1 3.96Å; I608-F647 HydrophobicContact CG2-CE1 3.38Å; I608-F647 HydrophobicContact CG2-CZ 4.36Å
609K92.2Very high92.2Very high71 Ų7151.8 Ų51.831%0.30927%0.271SS..Hα-helixtrans-67.1-36.4174.7-73.8178.170.3174.40112.7V605 D606 D607 D611 V612 K613V605-K609 HydrophobicContact CG2-CD 4.48Å; V605-K609 WeakPolarHBondContact O-CG 3.14Å; V605-K609 PolarHBondContact O-N 2.93Å; D606-K609 PolarHBondContact O-N 2.97Å; D607-K609 VanDerWaalsContact C-N 3.31Å; D607-K609 PolarHBondContact O-N 2.74Å; K609-D611 VanDerWaalsContact C-N 3.31Å; K609-V612 WeakPolarHBondContact O-CB 3.35Å; K609-V612 PolarHBondContact O-N 3.04Å; K609-K613 WeakPolarHBondContact O-CG 3.48Å; K609-K613 PolarHBondContact O-N 3.3Å; K609-K613 VanDerWaalsContact O-N 3.13Å
610N92.3Very high91.6Very high83 Ų8354.5 Ų54.544%0.44429%0.288SS..Hα-helixtrans-65.7-37.8174.8-72.1-27.7000111.1D606 D607 K613 A614D606-N610 WeakPolarHBondContact O-CB 3.47Å; D606-N610 PolarHBondContact O-N 3.45Å; D606-N610 PolarHBondContact O-ND2 3.49Å; D607-N610 WeakPolarHBondContact O-CB 3.44Å; D607-N610 PolarHBondContact O-N 3.32Å; D607-N610 VanDerWaalsContact O-N 3.16Å; N610-K613 PolarHBondContact O-N 3.33Å; N610-A614 PolarHBondContact O-N 2.92Å
611D92.2Very high90.9Very high8 Ų860.1 Ų60.14%0.04331%0.312CS..Hα-helixtrans-64-40.4172.7-72.3-28000111.7N595 Y597 D607 I608 K609 K613 A614 I615 F647 Y759N595-D611 PolarHBondContact ND2-OD2 2.82Å; Y597-D611 VanDerWaalsContact CZ-OD2 3.3Å; Y597-D611 PolarHBondContact OH-OD2 3.2Å; D607-D611 PolarHBondContact O-N 2.84Å; I608-D611 PolarHBondContact O-N 2.93Å; K609-D611 VanDerWaalsContact C-N 3.31Å; D611-K613 VanDerWaalsContact C-N 3.31Å; D611-K613 PolarHBondContact O-N 2.75Å; D611-A614 PolarHBondContact O-N 3.01Å; D611-A614 VanDerWaalsContact O-N 3.12Å; D611-I615 WeakPolarHBondContact O-CG1 3.25Å; D611-I615 PolarHBondContact O-N 2.98Å; D611-F647 HydrophobicContact CB-CZ 4.48Å; D611-Y759 PolarHBondContact OD1-OH 3.06Å
612V93.5Very high90.2Very high8 Ų858.6 Ų58.65%0.04832%0.317CS..Hα-helixtrans-55.9-44.9172.4168.70000112I608 K609 I615 A616 F647 E650 F655I608-V612 PolarHBondContact O-N 3.14Å; K609-V612 WeakPolarHBondContact O-CB 3.35Å; K609-V612 PolarHBondContact O-N 3.04Å; V612-I615 WeakPolarHBondContact O-CB 2.91Å; V612-I615 PolarHBondContact O-N 3.17Å; V612-A616 PolarHBondContact O-N 3.04Å; V612-F647 HydrophobicContact CG2-CB 4.46Å; V612-F647 HydrophobicContact CG2-CD1 3.28Å; V612-F647 HydrophobicContact CG2-CE1 3.57Å; V612-F647 HydrophobicContact CG2-CG 4Å; V612-E650 HydrophobicContact CB-CB 4.49Å; V612-E650 HydrophobicContact CG1-CB 3.82Å; V612-E650 HydrophobicContact CG2-CB 4.36Å; V612-F655 HydrophobicContact CG1-CE1 4.46Å; V612-F655 HydrophobicContact CG1-CZ 4.01Å
613K92.1Very high89.7Confident121 Ų12154.2 Ų54.253%0.52629%0.291SS..Hα-helixtrans-64.3-40.6176.2-66.1171.9-174168.30111.7K609 N610 D611 I615 A616 Q617K609-K613 WeakPolarHBondContact O-CG 3.48Å; K609-K613 PolarHBondContact O-N 3.3Å; K609-K613 VanDerWaalsContact O-N 3.13Å; N610-K613 PolarHBondContact O-N 3.33Å; D611-K613 VanDerWaalsContact C-N 3.31Å; D611-K613 PolarHBondContact O-N 2.75Å; K613-I615 VanDerWaalsContact C-N 3.34Å; K613-A616 WeakPolarHBondContact O-CB 3.48Å; K613-A616 PolarHBondContact O-N 3.13Å; K613-Q617 VanDerWaalsContact O-CG 3.3Å; K613-Q617 WeakPolarHBondContact O-CG 3.31Å; K613-Q617 PolarHBondContact O-N 3.17Å
614A89.7Confident89Confident18 Ų1856.9 Ų56.915%0.14930%0.303CS..Hα-helixtrans-65.9-37.2177.300000112N610 D611 K618 Y759N610-A614 PolarHBondContact O-N 2.92Å; D611-A614 PolarHBondContact O-N 3.01Å; D611-A614 VanDerWaalsContact O-N 3.12Å; A614-K618 WeakPolarHBondContact O-CB 3.29Å; A614-K618 WeakPolarHBondContact O-CG 3.17Å; A614-K618 PolarHBondContact O-N 3.35Å; A614-Y759 HydrophobicContact CB-CE1 3.95Å; A614-Y759 VanDerWaalsContact CB-OH 3.27Å; A614-Y759 WeakPolarHBondContact CB-OH 3.26Å
615I91.2Very high88.8Confident0 Ų056.7 Ų56.70%030%0.296CS..Hα-helixtrans-59.7-54.4173.3-66.5163.5000109.8V570 D611 V612 K613 Q617 K618 M619 Y626 F647 F655V570-I615 HydrophobicContact CG1-CD1 4.27Å; V570-I615 HydrophobicContact CG2-CD1 4.38Å; V570-I615 HydrophobicContact CG2-CG2 3.67Å; D611-I615 WeakPolarHBondContact O-CG1 3.25Å; D611-I615 PolarHBondContact O-N 2.98Å; V612-I615 WeakPolarHBondContact O-CB 2.91Å; V612-I615 PolarHBondContact O-N 3.17Å; K613-I615 VanDerWaalsContact C-N 3.34Å; I615-Q617 PolarHBondContact O-N 3.16Å; I615-K618 PolarHBondContact O-N 3.17Å; I615-K618 VanDerWaalsContact O-N 3.16Å; I615-M619 HydrophobicContact CG2-CE 3.87Å; I615-M619 HydrophobicContact CG2-CG 4.45Å; I615-M619 HydrophobicContact CG2-SD 4.2Å; I615-M619 WeakPolarHBondContact O-CG 3.38Å; I615-M619 PolarHBondContact O-N 2.89Å; I615-Y626 HydrophobicContact CB-CD2 4.27Å; I615-Y626 HydrophobicContact CB-CG 4.46Å; I615-Y626 HydrophobicContact CD1-CD1 3.85Å; I615-Y626 HydrophobicContact CD1-CE1 3.91Å; I615-Y626 HydrophobicContact CD1-CG 4.21Å; I615-Y626 HydrophobicContact CG1-CD1 3.66Å; I615-Y626 HydrophobicContact CG1-CD2 3.55Å; I615-Y626 HydrophobicContact CG1-CE1 3.71Å; I615-Y626 HydrophobicContact CG1-CE2 3.59Å; I615-Y626 HydrophobicContact CG1-CG 3.58Å; I615-Y626 HydrophobicContact CG2-CD2 4.42Å; I615-Y626 HydrophobicContact CG2-CG 4.32Å; I615-F647 HydrophobicContact CD1-CD2 4.08Å; I615-F647 HydrophobicContact CD1-CE2 3.66Å; I615-F647 HydrophobicContact CD1-CZ 3.99Å; I615-F655 HydrophobicContact CB-CE1 3.93Å; I615-F655 HydrophobicContact CB-CZ 4.18Å; I615-F655 HydrophobicContact CD1-CZ 4.4Å; I615-F655 HydrophobicContact CG2-CD1 3.58Å; I615-F655 HydrophobicContact CG2-CD2 4.4Å; I615-F655 HydrophobicContact CG2-CE1 3.45Å; I615-F655 VanDerWaalsContact CG2-CE1 3.45Å; I615-F655 HydrophobicContact CG2-CE2 4.28Å; I615-F655 HydrophobicContact CG2-CG 4.06Å; I615-F655 HydrophobicContact CG2-CZ 3.82Å
616A89.7Confident88.7Confident13 Ų1354.1 Ų54.111%0.10728%0.28CS..Hα-helixtrans-51.4-52.9177.800000111.9V612 K613 K618 M619 D620V612-A616 PolarHBondContact O-N 3.04Å; K613-A616 WeakPolarHBondContact O-CB 3.48Å; K613-A616 PolarHBondContact O-N 3.13Å; A616-K618 VanDerWaalsContact C-N 3.33Å; A616-K618 PolarHBondContact O-N 3.5Å; A616-M619 PolarHBondContact O-N 2.91Å; A616-M619 VanDerWaalsContact O-N 3.12Å; A616-D620 PolarHBondContact O-N 3.28Å
617Q88Confident88.8Confident120 Ų12049.1 Ų49.156%0.56125%0.253SS*.Hα-helixtrans-61.8-36.9179.9-71.7175.32.400113.5K613 I615 K621K613-Q617 VanDerWaalsContact O-CG 3.3Å; K613-Q617 WeakPolarHBondContact O-CG 3.31Å; K613-Q617 PolarHBondContact O-N 3.17Å; I615-Q617 PolarHBondContact O-N 3.16Å; Q617-K621 WeakPolarHBondContact O-CG 3.39Å; Q617-K621 PolarHBondContact O-N 3.3Å
618K86.5Confident88.9Confident32 Ų3245.4 Ų45.414%0.13923%0.233CC..Hα-helixtrans-66.5-42.1175.3-81177.6172.2-176.40111.1D594 A614 I615 A616 K621 G622 V623 Y626 A757D594-K618 IonicContact OD1-NZ 2.93Å; D594-K618 PolarHBondContact OD1-NZ 3.45Å; A614-K618 WeakPolarHBondContact O-CB 3.29Å; A614-K618 WeakPolarHBondContact O-CG 3.17Å; A614-K618 PolarHBondContact O-N 3.35Å; I615-K618 PolarHBondContact O-N 3.17Å; I615-K618 VanDerWaalsContact O-N 3.16Å; A616-K618 VanDerWaalsContact C-N 3.33Å; A616-K618 PolarHBondContact O-N 3.5Å; K618-K621 CarbonylContact O-C 3.57Å; K618-K621 PolarHBondContact O-N 2.86Å; K618-G622 PolarHBondContact O-N 2.86Å; K618-V623 HydrophobicContact CB-CB 4.19Å; K618-V623 HydrophobicContact CB-CG2 4.14Å; K618-V623 VanDerWaalsContact O-CB 3.26Å; K618-V623 WeakPolarHBondContact O-CB 3.4Å; K618-V623 WeakPolarHBondContact O-CG2 3.42Å; K618-V623 PolarHBondContact O-N 3.27Å; K618-V623 VanDerWaalsContact O-N 3.13Å; K618-Y626 HydrophobicContact CD-CD2 4.01Å; K618-Y626 HydrophobicContact CD-CE2 3.85Å; K618-A757 WeakPolarHBondContact CE-O 3.36Å; K618-A757 PolarHBondContact NZ-O 3.18Å
619M86.7Confident89Confident5 Ų545.4 Ų45.43%0.02523%0.233CC..Hα-helixtrans-68.4-38.1-179.4-65.8-167.2173.900112.3H568 V570 I615 A616 K621 G622 V623 F655H568-M619 HydrophobicContact CB-CE 4.48Å; H568-M619 HydrophobicContact CB-SD 3.54Å; H568-M619 VanDerWaalsContact CB-SD 3.54Å; V570-M619 HydrophobicContact CG2-CE 3.82Å; I615-M619 HydrophobicContact CG2-CE 3.87Å; I615-M619 HydrophobicContact CG2-CG 4.45Å; I615-M619 HydrophobicContact CG2-SD 4.2Å; I615-M619 WeakPolarHBondContact O-CG 3.38Å; I615-M619 PolarHBondContact O-N 2.89Å; A616-M619 PolarHBondContact O-N 2.91Å; A616-M619 VanDerWaalsContact O-N 3.12Å; M619-K621 PolarHBondContact O-N 2.86Å; M619-G622 PolarHBondContact O-N 2.89Å; M619-V623 WeakPolarHBondContact CA-O 3.46Å; M619-V623 WeakPolarHBondContact CG-O 3.5Å; M619-F655 HydrophobicContact CE-CB 3.92Å; M619-F655 HydrophobicContact CE-CG 4.44Å; M619-F655 HydrophobicContact SD-CB 3.41Å; M619-F655 WeakPolarHBondContact SD-CB 3.48Å; M619-F655 HydrophobicContact SD-CD1 4.12Å; M619-F655 HydrophobicContact SD-CG 4.08Å
620D84.6Confident89.3Confident122 Ų12242.3 Ų42.365%0.65222%0.219SC*.Hα-helixtrans-60.5-30171.9-72.2-18000112.6A616 G622A616-D620 PolarHBondContact O-N 3.28Å; D620-G622 PolarHBondContact O-N 2.88Å
621K81.6Confident89.6Confident164 Ų16438.3 Ų38.371%0.71320%0.198SC*.THydrogen-bonded Turntrans-83.810.5174.6-67.8176.5-178.1-178.50113.8Q617 K618 M619Q617-K621 WeakPolarHBondContact O-CG 3.39Å; Q617-K621 PolarHBondContact O-N 3.3Å; K618-K621 CarbonylContact O-C 3.57Å; K618-K621 PolarHBondContact O-N 2.86Å; M619-K621 PolarHBondContact O-N 2.86Å
622G78.8Confident89.8Confident46 Ų4640.7 Ų40.747%0.47421%0.209SC..THydrogen-bonded Turntrans98.6-1.4173.100000115.6K618 M619 D620 Q624K618-G622 PolarHBondContact O-N 2.86Å; M619-G622 PolarHBondContact O-N 2.89Å; D620-G622 PolarHBondContact O-N 2.88Å; G622-Q624 PolarHBondContact O-N 3.04Å; G622-Q624 PolarHBondContact O-NE2 3.31Å
623V80.9Confident90Very high42 Ų4243.1 Ų43.126%0.25522%0.222SC..  trans-68.7124.3177-179.80000109.8K618 M619 R625K618-V623 HydrophobicContact CB-CB 4.19Å; K618-V623 HydrophobicContact CB-CG2 4.14Å; K618-V623 VanDerWaalsContact O-CB 3.26Å; K618-V623 WeakPolarHBondContact O-CB 3.4Å; K618-V623 WeakPolarHBondContact O-CG2 3.42Å; K618-V623 PolarHBondContact O-N 3.27Å; K618-V623 VanDerWaalsContact O-N 3.13Å; M619-V623 WeakPolarHBondContact CA-O 3.46Å; M619-V623 WeakPolarHBondContact CG-O 3.5Å; V623-R625 WeakPolarHBondContact CG1-O 3.33Å
624Q81.4Confident90.2Very high80 Ų8037.6 Ų37.637%0.37420%0.199SC..  trans-85.1-20.1-175.3-65.7-59.6-49.900114.3H568 R569 G622H568-Q624 VanDerWaalsContact CA-O 3.28Å; H568-Q624 WeakPolarHBondContact CA-O 3.5Å; H568-Q624 PolarHBondContact N-O 3.27Å; R569-Q624 PolarHBondContact N-O 2.94Å; R569-Q624 VanDerWaalsContact N-O 3.14Å; G622-Q624 PolarHBondContact O-N 3.04Å; G622-Q624 PolarHBondContact O-NE2 3.31Å
625R89.4Confident90.5Very high19 Ų1938.8 Ų38.87%0.07220%0.203CC..EExtended strand (participates in β ladder)trans-139.8155.1-172.768168.3-170.282.5-3.6112.5D70 A563 R569 V623 I627D70-R625 IonicContact OD1-CZ 3.71Å; D70-R625 IonicContact OD1-NE 3.11Å; D70-R625 PolarHBondContact OD1-NE 3.44Å; D70-R625 IonicContact OD1-NH2 2.79Å; D70-R625 PolarHBondContact OD1-NH2 3.13Å; D70-R625 IonicContact OD2-NE 2.63Å; A563-R625 HydrophobicContact CB-CB 3.67Å; R569-R625 CarbonylContact O-C 3.58Å; R569-R625 VanDerWaalsContact O-CA 3.25Å; R569-R625 WeakPolarHBondContact O-CA 3.22Å; V623-R625 WeakPolarHBondContact CG1-O 3.33Å; R625-I627 VanDerWaalsContact NH1-CD1 3.31Å
626Y91.8Very high90.7Very high1 Ų146 Ų460%0.00424%0.238CC..EExtended strand (participates in β ladder)trans-136.5135.5168-165.2-84.8000109.7R569 V570 F571 D594 I615 K618 V628 Y759R569-Y626 PolarHBondContact O-N 3.4Å; V570-Y626 CarbonylContact C-O 3.5Å; V570-Y626 VanDerWaalsContact CA-O 3.29Å; V570-Y626 WeakPolarHBondContact CA-O 3.46Å; V570-Y626 HydrophobicContact CG1-CD1 4.21Å; F571-Y626 PolarHBondContact N-O 3.14Å; D594-Y626 HydrophobicContact CB-CD1 3.92Å; D594-Y626 HydrophobicContact CB-CD2 3.69Å; D594-Y626 HydrophobicContact CB-CE1 3.53Å; D594-Y626 HydrophobicContact CB-CE2 3.3Å; D594-Y626 HydrophobicContact CB-CG 3.98Å; D594-Y626 WeakPolarHBondContact OD2-CA 3.31Å; I615-Y626 HydrophobicContact CB-CD2 4.27Å; I615-Y626 HydrophobicContact CB-CG 4.46Å; I615-Y626 HydrophobicContact CD1-CD1 3.85Å; I615-Y626 HydrophobicContact CD1-CE1 3.91Å; I615-Y626 HydrophobicContact CD1-CG 4.21Å; I615-Y626 HydrophobicContact CG1-CD1 3.66Å; I615-Y626 HydrophobicContact CG1-CD2 3.55Å; I615-Y626 HydrophobicContact CG1-CE1 3.71Å; I615-Y626 HydrophobicContact CG1-CE2 3.59Å; I615-Y626 HydrophobicContact CG1-CG 3.58Å; I615-Y626 HydrophobicContact CG2-CD2 4.42Å; I615-Y626 HydrophobicContact CG2-CG 4.32Å; K618-Y626 HydrophobicContact CD-CD2 4.01Å; K618-Y626 HydrophobicContact CD-CE2 3.85Å; Y626-V628 HydrophobicContact CD1-CG2 3.89Å; Y626-V628 HydrophobicContact CE1-CG2 3.52Å; Y626-Y759 PolarHBondContact OH-OH 3.46Å
627I94Very high91Very high0 Ų051.7 Ų51.70%026%0.262CS..EExtended strand (participates in β ladder)trans-123.2130.5179.9-62.3-176.1000110.2V556 K560 F571 V573 A593 D594 N595 R625V556-I627 HydrophobicContact CG1-CD1 3.84Å; V556-I627 HydrophobicContact CG1-CG2 4.14Å; K560-I627 HydrophobicContact CB-CD1 4.49Å; K560-I627 HydrophobicContact CD-CD1 4.48Å; K560-I627 HydrophobicContact CG-CD1 3.4Å; K560-I627 VanDerWaalsContact CG-CD1 3.4Å; F571-I627 HydrophobicContact CB-CG1 4.43Å; V573-I627 HydrophobicContact CG2-CG2 4.32Å; A593-I627 HydrophobicContact CB-CB 4.31Å; A593-I627 HydrophobicContact CB-CG2 3.95Å; D594-I627 PolarHBondContact N-O 2.84Å; D594-I627 PolarHBondContact OD2-N 3.32Å; N595-I627 PolarHBondContact N-O 3.48Å; R625-I627 VanDerWaalsContact NH1-CD1 3.31Å
628V95.6Very high91.3Very high0 Ų048.8 Ų48.80%025%0.247CC..EExtended strand (participates in β ladder)trans-114.2130.4172.2171.50000108.2F571 I572 V573 N595 Y597 Y626 F647F571-V628 PolarHBondContact O-N 3.48Å; I572-V628 HydrophobicContact CG1-CB 4.43Å; I572-V628 HydrophobicContact CG2-CG1 4.3Å; V573-V628 PolarHBondContact N-O 3.06Å; N595-V628 WeakPolarHBondContact O-CA 3.46Å; Y597-V628 HydrophobicContact CD2-CG1 3.3Å; Y597-V628 HydrophobicContact CE2-CB 4.48Å; Y597-V628 HydrophobicContact CE2-CG1 3.36Å; Y597-V628 HydrophobicContact CE2-CG2 4.29Å; Y626-V628 HydrophobicContact CD1-CG2 3.89Å; Y626-V628 HydrophobicContact CE1-CG2 3.52Å; V628-F647 HydrophobicContact CG2-CE2 4.15Å
629T97.5Very high91.8Very high0 Ų050.1 Ų50.10%026%0.257CS..EExtended strand (participates in β ladder)trans-93.8141160.850.90000109.5V573 A584 A593 N595 A596 Y597V573-T629 CarbonylContact O-C 3.56Å; V573-T629 WeakPolarHBondContact O-CA 3.48Å; A584-T629 WeakPolarHBondContact O-CB 3.34Å; A584-T629 PolarHBondContact O-OG1 3.02Å; A593-T629 HydrophobicContact CB-CG2 4.27Å; N595-T629 PolarHBondContact O-N 3.41Å; N595-T629 PolarHBondContact O-OG1 2.93Å; A596-T629 CarbonylContact C-O 3.3Å; A596-T629 VanDerWaalsContact CA-O 3.23Å; A596-T629 WeakPolarHBondContact CA-O 3.44Å; A596-T629 VanDerWaalsContact CB-OG1 3.31Å; A596-T629 WeakPolarHBondContact CB-OG1 3.41Å; Y597-T629 PolarHBondContact N-O 3.35Å
630R97.7Very high92.2Very high6 Ų650 Ų502%0.02326%0.257CS..EExtended strand (participates in β ladder)trans-133.6127.1177.5172.5179171-70.6-13.6108.9I572 V573 E574 T575 Y597 E632 A634 N635 Y638 T640I572-R630 HydrophobicContact CG2-CB 4.29Å; V573-R630 PolarHBondContact O-N 2.82Å; E574-R630 CarbonylContact C-O 3.59Å; E574-R630 VanDerWaalsContact CA-O 3.27Å; E574-R630 WeakPolarHBondContact CA-O 3.41Å; E574-R630 IonicContact OE2-NH1 2.75Å; E574-R630 PolarHBondContact OE2-NH1 3.37Å; T575-R630 PolarHBondContact N-O 2.9Å; T575-R630 PolarHBondContact OG1-O 3.46Å; Y597-R630 WeakPolarHBondContact O-CA 3.46Å; R630-E632 PolarHBondContact NH1-O 3.34Å; R630-E632 PolarHBondContact NH2-O 3.41Å; R630-A634 HydrophobicContact CG-CB 4.21Å; R630-N635 PolarHBondContact NH2-O 2.99Å; R630-Y638 PolarHBondContact NE-O 2.92Å; R630-Y638 VanDerWaalsContact NE-O 3.09Å; R630-Y638 PolarHBondContact NH2-O 3.31Å; R630-T640 WeakPolarHBondContact CD-OG1 3.34Å; R630-T640 PolarHBondContact NH1-OG1 2.95Å
631C98Very high92.8Very high0 Ų047.6 Ų47.60%024%0.242CC..EExtended strand (participates in β ladder)trans-70.3139.3169.4-168.60000110.2G578 C580 A584 Y597 N633 A634G578-C631 PolarHBondContact O-SG 3.43Å; C580-C631 PolarHBondContact O-SG 3.5Å; A584-C631 HydrophobicContact CB-CB 4.07Å; Y597-C631 PolarHBondContact O-N 3.42Å; C631-N633 VanDerWaalsContact C-N 3.26Å; C631-N633 PolarHBondContact O-N 2.87Å; C631-A634 HydrophobicContact CB-CB 4.23Å; C631-A634 WeakPolarHBondContact O-CB 3.42Å; C631-A634 PolarHBondContact O-N 3.29Å
632E96.5Very high93.5Very high57 Ų5743.1 Ų43.127%0.26622%0.223SC..THydrogen-bonded Turntrans-50.2-43-175.662.8-168159.600113.2E574 T575 G577 G578 R630E574-E632 HydrophobicContact CG-CB 4.27Å; T575-E632 PolarHBondContact O-N 2.99Å; G577-E632 PolarHBondContact N-OE1 2.78Å; G578-E632 WeakPolarHBondContact CA-OE1 3.42Å; G578-E632 PolarHBondContact N-OE1 2.79Å; R630-E632 PolarHBondContact NH1-O 3.34Å; R630-E632 PolarHBondContact NH2-O 3.41Å
633N97.1Very high94.4Very high59 Ų5941 Ų4132%0.31620%0.2SC..THydrogen-bonded Turntrans-103.526.7177.5-54.8-17.1000113.6G578 Y579 C631 N635G578-N633 VanDerWaalsContact O-CB 3.26Å; G578-N633 WeakPolarHBondContact O-CB 3.44Å; G578-N633 PolarHBondContact O-N 2.87Å; Y579-N633 HydrophobicContact CD1-CB 3.59Å; Y579-N633 HydrophobicContact CE1-CB 3.65Å; Y579-N633 HydrophobicContact CG-CB 4.07Å; C631-N633 VanDerWaalsContact C-N 3.26Å; C631-N633 PolarHBondContact O-N 2.87Å; N633-N635 PolarHBondContact O-N 3.3Å
634A97.1Very high95.1Very high5 Ų542.2 Ų42.24%0.04120%0.2CC..SBendtrans-55.6-38.5176.900000112.3F603 R630 C631F603-A634 HydrophobicContact CE1-CB 4.04Å; F603-A634 HydrophobicContact CZ-CB 4.14Å; R630-A634 HydrophobicContact CG-CB 4.21Å; C631-A634 HydrophobicContact CB-CB 4.23Å; C631-A634 WeakPolarHBondContact O-CB 3.42Å; C631-A634 PolarHBondContact O-N 3.29Å
635N96.8Very high95.8Very high44 Ų4443.2 Ų43.224%0.23521%0.205CC..  trans-156140.2169.8-171.5-74.3000109.4F603 R630 N633 H637 Y638F603-N635 HydrophobicContact CE1-CB 4.22Å; F603-N635 HydrophobicContact CE2-CB 4.28Å; F603-N635 HydrophobicContact CZ-CB 3.67Å; R630-N635 PolarHBondContact NH2-O 2.99Å; N633-N635 PolarHBondContact O-N 3.3Å; N635-H637 PolarHBondContact OD1-N 3.48Å; N635-Y638 HydrophobicContact CB-CD2 3.96Å; N635-Y638 HydrophobicContact CB-CG 4.36Å; N635-Y638 VanDerWaalsContact CG-CD2 3.42Å; N635-Y638 PolarHBondContact OD1-N 3.4Å
636M94.4Very high96.1Very high152 Ų15243.5 Ų43.575%0.74921%0.208SC*.SBendtrans-67.9-34-178.6-177.3171.469.300113.3
637H95.7Very high96.2Very high132 Ų13243.5 Ų43.561%0.61121%0.208SC*.SBendtrans-97.3-37.2-175.9-59.5-62.8000112.2N635 T639N635-H637 PolarHBondContact OD1-N 3.48Å; H637-T639 PolarHBondContact O-N 3.01Å
638Y95.7Very high96.2Very high59 Ų5945.4 Ų45.423%0.23122%0.221CC..SBendtrans-83.870175.8-47.2-42.1000110.4F603 I608 R630 N635 F642F603-Y638 HydrophobicContact CD2-CD2 4.01Å; F603-Y638 AromaticContact CE2-CD2 3.69Å; F603-Y638 HydrophobicContact CE2-CD2 3.69Å; F603-Y638 HydrophobicContact CE2-CG 4.26Å; F603-Y638 HydrophobicContact CZ-CD2 4.45Å; F603-Y638 WeakPolarHBondContact O-CE2 3.38Å; I608-Y638 HydrophobicContact CD1-CD1 4.49Å; I608-Y638 HydrophobicContact CD1-CD2 4.19Å; I608-Y638 HydrophobicContact CD1-CG 4.06Å; R630-Y638 PolarHBondContact NE-O 2.92Å; R630-Y638 VanDerWaalsContact NE-O 3.09Å; R630-Y638 PolarHBondContact NH2-O 3.31Å; N635-Y638 HydrophobicContact CB-CD2 3.96Å; N635-Y638 HydrophobicContact CB-CG 4.36Å; N635-Y638 VanDerWaalsContact CG-CD2 3.42Å; N635-Y638 PolarHBondContact OD1-N 3.4Å; Y638-F642 AromaticContact CD1-CD1 3.9Å; Y638-F642 HydrophobicContact CD1-CD1 3.9Å; Y638-F642 AromaticContact CD1-CE1 3.61Å; Y638-F642 HydrophobicContact CD1-CE1 3.61Å; Y638-F642 HydrophobicContact CD1-CZ 4.3Å; Y638-F642 HydrophobicContact CE1-CE1 4.23Å; Y638-F642 HydrophobicContact CG-CE1 4.45Å
639T96Very high96.2Very high59 Ų5952.2 Ų52.236%0.36225%0.253SS..  trans-67.7160.4177.568.10000111.4H637 E641 F642 M643H637-T639 PolarHBondContact O-N 3.01Å; T639-E641 PolarHBondContact O-N 3.08Å; T639-F642 PolarHBondContact O-N 3.38Å; T639-F642 VanDerWaalsContact O-N 3.11Å; T639-F642 WeakPolarHBondContact OG1-CB 3.36Å; T639-F642 PolarHBondContact OG1-N 2.93Å; T639-F642 VanDerWaalsContact OG1-N 3.08Å; T639-M643 WeakPolarHBondContact O-CG 3.41Å; T639-M643 PolarHBondContact O-N 2.95Å
640T96.6Very high96Very high4 Ų455.9 Ų55.93%0.02527%0.27CS..Hα-helixtrans-54-37.2174.4-65.80000112I572 E574 R630 R644 I659I572-T640 HydrophobicContact CG2-CG2 4.05Å; E574-T640 HydrophobicContact CB-CG2 4.49Å; E574-T640 VanDerWaalsContact OE2-CB 3.28Å; E574-T640 WeakPolarHBondContact OE2-CB 3.33Å; E574-T640 PolarHBondContact OE2-OG1 3.44Å; R630-T640 WeakPolarHBondContact CD-OG1 3.34Å; R630-T640 PolarHBondContact NH1-OG1 2.95Å; T640-R644 WeakPolarHBondContact O-CB 3.3Å; T640-R644 PolarHBondContact O-N 3.37Å; T640-I659 HydrophobicContact CG2-CB 3.66Å; T640-I659 HydrophobicContact CG2-CD1 4.27Å; T640-I659 HydrophobicContact CG2-CG2 3.46Å; T640-I659 VanDerWaalsContact CG2-CG2 3.46Å
641E96.6Very high95.6Very high70 Ų7055.7 Ų55.733%0.32727%0.27SS..Hα-helixtrans-71.9-42177.8-177.853.5-153.800112.3T639 M643 R644 Q645T639-E641 PolarHBondContact O-N 3.08Å; E641-M643 VanDerWaalsContact C-N 3.35Å; E641-M643 PolarHBondContact O-N 3.1Å; E641-R644 VanDerWaalsContact CD-NE 3.33Å; E641-R644 WeakPolarHBondContact O-CB 3.49Å; E641-R644 PolarHBondContact O-N 2.92Å; E641-R644 IonicContact OE1-CZ 3.25Å; E641-R644 VanDerWaalsContact OE1-CZ 3.25Å; E641-R644 IonicContact OE1-NE 3.33Å; E641-R644 PolarHBondContact OE1-NE 3.34Å; E641-R644 IonicContact OE1-NH2 2.66Å; E641-R644 PolarHBondContact OE1-NH2 3.32Å; E641-R644 IonicContact OE2-CZ 3.91Å; E641-R644 IonicContact OE2-NE 3.52Å; E641-R644 PolarHBondContact OE2-NE 3.45Å; E641-Q645 WeakPolarHBondContact O-CG 3.25Å; E641-Q645 PolarHBondContact O-N 3.45Å; E641-Q645 PolarHBondContact OE1-NE2 3.05Å
642F96.4Very high95.2Very high71 Ų7164 Ų6431%0.31131%0.306SS..Hα-helixtrans-58.4-48.2173.2173.2-94.3000111.3Y638 T639 R644 Q645 L646Y638-F642 AromaticContact CD1-CD1 3.9Å; Y638-F642 HydrophobicContact CD1-CD1 3.9Å; Y638-F642 AromaticContact CD1-CE1 3.61Å; Y638-F642 HydrophobicContact CD1-CE1 3.61Å; Y638-F642 HydrophobicContact CD1-CZ 4.3Å; Y638-F642 HydrophobicContact CE1-CE1 4.23Å; Y638-F642 HydrophobicContact CG-CE1 4.45Å; T639-F642 PolarHBondContact O-N 3.38Å; T639-F642 VanDerWaalsContact O-N 3.11Å; T639-F642 WeakPolarHBondContact OG1-CB 3.36Å; T639-F642 PolarHBondContact OG1-N 2.93Å; T639-F642 VanDerWaalsContact OG1-N 3.08Å; F642-R644 VanDerWaalsContact C-N 3.3Å; F642-R644 PolarHBondContact O-N 3.23Å; F642-Q645 PolarHBondContact O-N 3.2Å; F642-Q645 VanDerWaalsContact O-N 3.16Å; F642-L646 HydrophobicContact CE1-CD2 4.03Å; F642-L646 HydrophobicContact CZ-CD2 4.35Å; F642-L646 WeakPolarHBondContact O-CB 3.34Å; F642-L646 PolarHBondContact O-N 2.9Å
643M96.3Very high94.8Very high0 Ų064.7 Ų64.70%033%0.329CS..Hα-helixtrans-62.8-37.3179.4-64.5-175.57200112I572 Y597 I608 T639 E641 L646 F647I572-M643 HydrophobicContact CD1-CB 3.75Å; Y597-M643 HydrophobicContact CD1-CE 4.18Å; Y597-M643 HydrophobicContact CD2-CE 3.39Å; Y597-M643 HydrophobicContact CD2-SD 4.29Å; Y597-M643 HydrophobicContact CE1-CE 3.94Å; Y597-M643 HydrophobicContact CE2-CE 3.08Å; Y597-M643 HydrophobicContact CE2-SD 4.48Å; Y597-M643 HydrophobicContact CG-CE 3.93Å; I608-M643 HydrophobicContact CD1-CE 4.32Å; I608-M643 HydrophobicContact CD1-CG 4.48Å; I608-M643 HydrophobicContact CG1-CE 4.26Å; I608-M643 HydrophobicContact CG2-CE 4.19Å; T639-M643 WeakPolarHBondContact O-CG 3.41Å; T639-M643 PolarHBondContact O-N 2.95Å; E641-M643 VanDerWaalsContact C-N 3.35Å; E641-M643 PolarHBondContact O-N 3.1Å; M643-L646 PolarHBondContact O-N 3.4Å; M643-F647 VanDerWaalsContact O-CB 3.28Å; M643-F647 WeakPolarHBondContact O-CB 3.39Å; M643-F647 WeakPolarHBondContact O-CG 3.33Å; M643-F647 PolarHBondContact O-N 3.11Å
644R96.2Very high94.4Very high69 Ų6966.2 Ų66.226%0.2633%0.334SS..Hα-helixtrans-59.6-47.5173.3-173.5-161.969.273.4-4.3111.6T640 E641 F642 S648 T657 I659T640-R644 WeakPolarHBondContact O-CB 3.3Å; T640-R644 PolarHBondContact O-N 3.37Å; E641-R644 VanDerWaalsContact CD-NE 3.33Å; E641-R644 WeakPolarHBondContact O-CB 3.49Å; E641-R644 PolarHBondContact O-N 2.92Å; E641-R644 IonicContact OE1-CZ 3.25Å; E641-R644 VanDerWaalsContact OE1-CZ 3.25Å; E641-R644 IonicContact OE1-NE 3.33Å; E641-R644 PolarHBondContact OE1-NE 3.34Å; E641-R644 IonicContact OE1-NH2 2.66Å; E641-R644 PolarHBondContact OE1-NH2 3.32Å; E641-R644 IonicContact OE2-CZ 3.91Å; E641-R644 IonicContact OE2-NE 3.52Å; E641-R644 PolarHBondContact OE2-NE 3.45Å; F642-R644 VanDerWaalsContact C-N 3.3Å; F642-R644 PolarHBondContact O-N 3.23Å; R644-S648 VanDerWaalsContact O-CB 3.32Å; R644-S648 WeakPolarHBondContact O-CB 3.46Å; R644-S648 PolarHBondContact O-N 2.98Å; R644-S648 PolarHBondContact O-OG 2.72Å; R644-T657 HydrophobicContact CB-CG2 4.49Å; R644-T657 HydrophobicContact CG-CG2 4.08Å; R644-I659 HydrophobicContact CB-CG2 3.52Å; R644-I659 HydrophobicContact CG-CG2 3.71Å
645Q96.1Very high94.2Very high100 Ų10066.6 Ų66.647%0.46734%0.335SS..Hα-helixtrans-63-49.3-179.7-70173.46.700110.3E641 F642 F647 S648 E649E641-Q645 WeakPolarHBondContact O-CG 3.25Å; E641-Q645 PolarHBondContact O-N 3.45Å; E641-Q645 PolarHBondContact OE1-NE2 3.05Å; F642-Q645 PolarHBondContact O-N 3.2Å; F642-Q645 VanDerWaalsContact O-N 3.16Å; Q645-F647 PolarHBondContact O-N 3.29Å; Q645-S648 PolarHBondContact O-N 3.46Å; Q645-E649 WeakPolarHBondContact O-CB 3.15Å; Q645-E649 PolarHBondContact O-N 3.38Å
646L95.2Very high94Very high26 Ų2666.1 Ų66.114%0.13634%0.335CS..Hα-helixtrans-60-48178.4-175.964.6000112.1V605 I608 F642 M643 S648 E649 E650V605-L646 HydrophobicContact CG2-CD2 4.04Å; I608-L646 HydrophobicContact CB-CD2 4.11Å; I608-L646 HydrophobicContact CG2-CD2 3.57Å; F642-L646 HydrophobicContact CE1-CD2 4.03Å; F642-L646 HydrophobicContact CZ-CD2 4.35Å; F642-L646 WeakPolarHBondContact O-CB 3.34Å; F642-L646 PolarHBondContact O-N 2.9Å; M643-L646 PolarHBondContact O-N 3.4Å; L646-S648 VanDerWaalsContact C-N 3.29Å; L646-S648 PolarHBondContact O-N 3.48Å; L646-E649 PolarHBondContact O-N 2.91Å; L646-E650 HydrophobicContact CD1-CG 3.64Å; L646-E650 HydrophobicContact CG-CG 4.26Å; L646-E650 VanDerWaalsContact O-CB 3.3Å; L646-E650 WeakPolarHBondContact O-CB 3.47Å; L646-E650 WeakPolarHBondContact O-CG 3.48Å; L646-E650 PolarHBondContact O-N 2.9Å
647F95.5Very high94Very high0 Ų059 Ų590%030%0.3CS..Hα-helixtrans-61.6-37.7177-82.516.6000112.5V570 I572 I608 D611 V612 I615 V628 M643 Q645 G651 F655 T657V570-F647 HydrophobicContact CG1-CD2 3.88Å; V570-F647 HydrophobicContact CG1-CE2 4.07Å; I572-F647 HydrophobicContact CD1-CD2 3.94Å; I572-F647 HydrophobicContact CD1-CE2 4.19Å; I572-F647 HydrophobicContact CD1-CG 4.48Å; I572-F647 HydrophobicContact CG1-CD2 4.3Å; I572-F647 HydrophobicContact CG1-CE2 4.32Å; I608-F647 HydrophobicContact CG2-CD1 3.96Å; I608-F647 HydrophobicContact CG2-CE1 3.38Å; I608-F647 HydrophobicContact CG2-CZ 4.36Å; D611-F647 HydrophobicContact CB-CZ 4.48Å; V612-F647 HydrophobicContact CG2-CB 4.46Å; V612-F647 HydrophobicContact CG2-CD1 3.28Å; V612-F647 HydrophobicContact CG2-CE1 3.57Å; V612-F647 HydrophobicContact CG2-CG 4Å; I615-F647 HydrophobicContact CD1-CD2 4.08Å; I615-F647 HydrophobicContact CD1-CE2 3.66Å; I615-F647 HydrophobicContact CD1-CZ 3.99Å; V628-F647 HydrophobicContact CG2-CE2 4.15Å; M643-F647 VanDerWaalsContact O-CB 3.28Å; M643-F647 WeakPolarHBondContact O-CB 3.39Å; M643-F647 WeakPolarHBondContact O-CG 3.33Å; M643-F647 PolarHBondContact O-N 3.11Å; Q645-F647 PolarHBondContact O-N 3.29Å; F647-G651 WeakPolarHBondContact O-CA 3.27Å; F647-G651 PolarHBondContact O-N 3.26Å; F647-F655 HydrophobicContact CB-CE2 4.37Å; F647-F655 WeakPolarHBondContact O-CE2 3.42Å; F647-T657 HydrophobicContact CB-CG2 3.92Å; F647-T657 WeakPolarHBondContact CB-OG1 3.33Å; F647-T657 HydrophobicContact CD2-CG2 4.12Å
648S93.6Very high94Very high40 Ų4058.6 Ų58.628%0.2829%0.293SS..Hα-helixtrans-70.1-41.8-179.6-56.10000111.6R644 Q645 L646R644-S648 VanDerWaalsContact O-CB 3.32Å; R644-S648 WeakPolarHBondContact O-CB 3.46Å; R644-S648 PolarHBondContact O-N 2.98Å; R644-S648 PolarHBondContact O-OG 2.72Å; Q645-S648 PolarHBondContact O-N 3.46Å; L646-S648 VanDerWaalsContact C-N 3.29Å; L646-S648 PolarHBondContact O-N 3.48Å
649E94.8Very high94.1Very high143 Ų14358.4 Ų58.467%0.66830%0.295SS*.Hα-helixtrans-72.5-53.3-179.4-171.959.5-149.600111.3Q645 L646 G651 K652Q645-E649 WeakPolarHBondContact O-CB 3.15Å; Q645-E649 PolarHBondContact O-N 3.38Å; L646-E649 PolarHBondContact O-N 2.91Å; E649-G651 VanDerWaalsContact C-N 3.27Å; E649-G651 PolarHBondContact O-N 3.45Å; E649-K652 WeakPolarHBondContact O-CG 3.36Å; E649-K652 PolarHBondContact O-N 3.35Å; E649-K652 VanDerWaalsContact O-N 3.09Å
650E93.3Very high94.1Very high78 Ų7858.1 Ų58.136%0.36429%0.292SS..Hα-helixtrans-71-24.2-178-65.8-69.9145.900112.5V612 L646 K652V612-E650 HydrophobicContact CB-CB 4.49Å; V612-E650 HydrophobicContact CG1-CB 3.82Å; V612-E650 HydrophobicContact CG2-CB 4.36Å; L646-E650 HydrophobicContact CD1-CG 3.64Å; L646-E650 HydrophobicContact CG-CG 4.26Å; L646-E650 VanDerWaalsContact O-CB 3.3Å; L646-E650 WeakPolarHBondContact O-CB 3.47Å; L646-E650 WeakPolarHBondContact O-CG 3.48Å; L646-E650 PolarHBondContact O-N 2.9Å; E650-K652 PolarHBondContact O-N 3.35Å
651G90.2Very high94.1Very high2 Ų262 Ų622%0.02132%0.315CS..THydrogen-bonded Turntrans-68.7-15.2172.400000113.8F647 E649 G653 Q654F647-G651 WeakPolarHBondContact O-CA 3.27Å; F647-G651 PolarHBondContact O-N 3.26Å; E649-G651 VanDerWaalsContact C-N 3.27Å; E649-G651 PolarHBondContact O-N 3.45Å; G651-G653 PolarHBondContact O-N 3.43Å; G651-Q654 VanDerWaalsContact O-CB 3.31Å; G651-Q654 WeakPolarHBondContact O-CB 3.35Å; G651-Q654 WeakPolarHBondContact O-CG 3.25Å; G651-Q654 PolarHBondContact O-N 3.03Å
652K90.4Very high94.2Very high173 Ų17359.6 Ų59.675%0.75230%0.304SS*.THydrogen-bonded Turntrans45.440.6173.6-62.8-175.8-178.9-1770114.6E649 E650 Q654E649-K652 WeakPolarHBondContact O-CG 3.36Å; E649-K652 PolarHBondContact O-N 3.35Å; E649-K652 VanDerWaalsContact O-N 3.09Å; E650-K652 PolarHBondContact O-N 3.35Å; K652-Q654 VanDerWaalsContact C-N 3.26Å; K652-Q654 PolarHBondContact O-N 3.37Å
653G87.5Confident94.1Very high72 Ų7257.2 Ų57.274%0.74230%0.3SS*.THydrogen-bonded Turntrans76.3-0.4178.800000115.9G651 F655G651-G653 PolarHBondContact O-N 3.43Å; G653-F655 PolarHBondContact O-N 2.83Å
654Q89.3Confident94.1Very high92 Ų9263.7 Ų63.743%0.4333%0.33SS..SBendtrans-63.9-29172.9-64.4-175.9-200111.8H568 G651 K652H568-Q654 WeakPolarHBondContact CB-O 3.37Å; H568-Q654 PolarHBondContact ND1-O 2.98Å; G651-Q654 VanDerWaalsContact O-CB 3.31Å; G651-Q654 WeakPolarHBondContact O-CB 3.35Å; G651-Q654 WeakPolarHBondContact O-CG 3.25Å; G651-Q654 PolarHBondContact O-N 3.03Å; K652-Q654 VanDerWaalsContact C-N 3.26Å; K652-Q654 PolarHBondContact O-N 3.37Å
655F92.1Very high94.1Very high12 Ų1262.7 Ų62.75%0.05334%0.336CS..SBendtrans-149.5159.817657.3-102.2000112.6H568 V570 V612 I615 M619 F647 G653H568-F655 HydrophobicContact CB-CB 4.11Å; H568-F655 VanDerWaalsContact O-CA 3.31Å; H568-F655 WeakPolarHBondContact O-CA 3.41Å; H568-F655 WeakPolarHBondContact O-CB 3.28Å; V570-F655 HydrophobicContact CB-CD2 4.3Å; V570-F655 HydrophobicContact CG2-CB 4.22Å; V570-F655 HydrophobicContact CG2-CD2 3.31Å; V570-F655 HydrophobicContact CG2-CE2 3.7Å; V570-F655 HydrophobicContact CG2-CG 3.81Å; V570-F655 HydrophobicContact CG2-CZ 4.48Å; V612-F655 HydrophobicContact CG1-CE1 4.46Å; V612-F655 HydrophobicContact CG1-CZ 4.01Å; I615-F655 HydrophobicContact CB-CE1 3.93Å; I615-F655 HydrophobicContact CB-CZ 4.18Å; I615-F655 HydrophobicContact CD1-CZ 4.4Å; I615-F655 HydrophobicContact CG2-CD1 3.58Å; I615-F655 HydrophobicContact CG2-CD2 4.4Å; I615-F655 HydrophobicContact CG2-CE1 3.45Å; I615-F655 VanDerWaalsContact CG2-CE1 3.45Å; I615-F655 HydrophobicContact CG2-CE2 4.28Å; I615-F655 HydrophobicContact CG2-CG 4.06Å; I615-F655 HydrophobicContact CG2-CZ 3.82Å; M619-F655 HydrophobicContact CE-CB 3.92Å; M619-F655 HydrophobicContact CE-CG 4.44Å; M619-F655 HydrophobicContact SD-CB 3.41Å; M619-F655 WeakPolarHBondContact SD-CB 3.48Å; M619-F655 HydrophobicContact SD-CD1 4.12Å; M619-F655 HydrophobicContact SD-CG 4.08Å; F647-F655 HydrophobicContact CB-CE2 4.37Å; F647-F655 WeakPolarHBondContact O-CE2 3.42Å; G653-F655 PolarHBondContact O-N 2.83Å
656S92.8Very high94.2Very high35 Ų3558 Ų5825%0.24531%0.314CS..EExtended strand (participates in β ladder)trans-102.2136.6174.262.20000111.5H568 R569 V570H568-S656 PolarHBondContact O-N 3.32Å; R569-S656 WeakPolarHBondContact CA-O 3.26Å; R569-S656 PolarHBondContact NE-OG 3.02Å; R569-S656 VanDerWaalsContact NE-OG 3.16Å; V570-S656 PolarHBondContact N-O 2.91Å
657T94.8Very high94.2Very high1 Ų158.6 Ų58.61%0.00632%0.317CS..EExtended strand (participates in β ladder)trans-106.9136.9178.2-51.10000111.8V570 I572 R644 F647V570-T657 HydrophobicContact CB-CG2 4.3Å; V570-T657 HydrophobicContact CG1-CG2 4.35Å; V570-T657 CarbonylContact O-C 3.52Å; V570-T657 WeakPolarHBondContact O-CA 3.23Å; I572-T657 HydrophobicContact CD1-CG2 4.02Å; I572-T657 HydrophobicContact CG1-CG2 4.21Å; R644-T657 HydrophobicContact CB-CG2 4.49Å; R644-T657 HydrophobicContact CG-CG2 4.08Å; F647-T657 HydrophobicContact CB-CG2 3.92Å; F647-T657 WeakPolarHBondContact CB-OG1 3.33Å; F647-T657 HydrophobicContact CD2-CG2 4.12Å
658R95.2Very high94.1Very high124 Ų12460 Ų6047%0.46833%0.331SS..EExtended strand (participates in β ladder)trans-132.5150.5174.9-68.3-65.4179.4-93.35.2110.5V570 F571 I572V570-R658 PolarHBondContact O-N 3.31Å; F571-R658 CarbonylContact C-O 3.48Å; F571-R658 WeakPolarHBondContact CA-O 3.29Å; F571-R658 HydrophobicContact CD1-CB 3.7Å; F571-R658 HydrophobicContact CE1-CB 3.6Å; F571-R658 HydrophobicContact CE1-CG 4.3Å; I572-R658 PolarHBondContact N-O 3.32Å
659I96.6Very high94.1Very high56 Ų5660.5 Ų60.529%0.28734%0.343SS..EExtended strand (participates in β ladder)trans-110.4148.617761.4170.6000110I572 T640 R644I572-I659 HydrophobicContact CB-CG2 4.28Å; I572-I659 CarbonylContact O-C 3.54Å; I572-I659 VanDerWaalsContact O-CA 3.31Å; I572-I659 WeakPolarHBondContact O-CA 3.44Å; T640-I659 HydrophobicContact CG2-CB 3.66Å; T640-I659 HydrophobicContact CG2-CD1 4.27Å; T640-I659 HydrophobicContact CG2-CG2 3.46Å; T640-I659 VanDerWaalsContact CG2-CG2 3.46Å; R644-I659 HydrophobicContact CB-CG2 3.52Å; R644-I659 HydrophobicContact CG-CG2 3.71Å
660N96.8Very high94.1Very high53 Ų5357.5 Ų57.528%0.28333%0.331SS..EExtended strand (participates in β ladder)trans-136.1113.8167.2-81.9-84000108.9L559 F571 I572 V573 E574 L662L559-N660 HydrophobicContact CD1-CB 3.99Å; L559-N660 WeakPolarHBondContact CD2-ND2 3.37Å; F571-N660 WeakPolarHBondContact CD1-ND2 3.43Å; I572-N660 PolarHBondContact O-N 3.02Å; V573-N660 CarbonylContact C-O 3.58Å; V573-N660 WeakPolarHBondContact CA-O 3.33Å; E574-N660 PolarHBondContact N-O 3.49Å; N660-L662 HydrophobicContact CB-CD2 4.24Å
661V97.3Very high94.2Very high84 Ų8454 Ų5451%0.50932%0.315SS..EExtended strand (participates in β ladder)trans-93.5106.5171.8-179.30000107.5E574 G663E574-V661 HydrophobicContact CB-CB 4.45Å; E574-V661 HydrophobicContact CB-CG1 4.45Å; E574-V661 HydrophobicContact CB-CG2 4.1Å; E574-V661 WeakPolarHBondContact OE1-CG1 3.47Å; V661-G663 VanDerWaalsContact C-N 3.3Å; V661-G663 PolarHBondContact O-N 3.02Å
662L97Very high94.6Very high20 Ų2054.2 Ų54.211%0.10532%0.317CS..  trans-71.1-30.7-172.2-54.9-170.7000112.1I552 M555 V573 E574 N660 Q666I552-L662 HydrophobicContact CB-CD1 4.2Å; I552-L662 HydrophobicContact CG1-CD1 3.97Å; I552-L662 HydrophobicContact CG2-CD1 3.82Å; M555-L662 HydrophobicContact CB-CD1 4.35Å; M555-L662 HydrophobicContact CB-CD2 4.13Å; M555-L662 HydrophobicContact SD-CB 4.02Å; M555-L662 HydrophobicContact SD-CD1 3.96Å; M555-L662 HydrophobicContact SD-CD2 3.61Å; M555-L662 HydrophobicContact SD-CG 4.05Å; V573-L662 HydrophobicContact CG1-CD1 3.72Å; V573-L662 HydrophobicContact CG1-CD2 3.83Å; V573-L662 HydrophobicContact CG1-CG 3.75Å; E574-L662 PolarHBondContact O-N 3.45Å; N660-L662 HydrophobicContact CB-CD2 4.24Å; L662-Q666 HydrophobicContact CB-CG 3.86Å; L662-Q666 HydrophobicContact CD1-CG 4.32Å
663G95.9Very high94.9Very high21 Ų2146.1 Ų46.122%0.21628%0.282CS..G310 helixtrans55.9-146177.300000113.2M576 V661 A665 Q666M576-G663 VanDerWaalsContact SD-O 3.37Å; V661-G663 VanDerWaalsContact C-N 3.3Å; V661-G663 PolarHBondContact O-N 3.02Å; G663-A665 PolarHBondContact O-N 3.33Å; G663-A665 VanDerWaalsContact O-N 3.1Å; G663-Q666 WeakPolarHBondContact O-CB 3.45Å; G663-Q666 WeakPolarHBondContact O-CG 3.48Å; G663-Q666 PolarHBondContact O-N 2.87Å; G663-Q666 PolarHBondContact O-NE2 3.31Å
664H96.2Very high95.3Very high137 Ų13744.1 Ų44.163%0.63425%0.253SS*.G310 helixtrans-65.6-13.7-171.7-71.782.1000115Q666 Q667H664-Q666 PolarHBondContact O-N 3.45Å; H664-Q666 VanDerWaalsContact O-N 3.08Å; H664-Q667 WeakPolarHBondContact O-CB 3.3Å; H664-Q667 PolarHBondContact O-N 2.84Å
665A95.9Very high95.6Very high48 Ų4839.8 Ų39.840%0.39723%0.232SC..G310 helixtrans-56.9-27.6174.600000111.9V551 M555 G663 Q667 G668V551-A665 WeakPolarHBondContact CG1-O 3.42Å; M555-A665 HydrophobicContact CE-CB 3.37Å; G663-A665 PolarHBondContact O-N 3.33Å; G663-A665 VanDerWaalsContact O-N 3.1Å; A665-Q667 PolarHBondContact O-N 3.36Å; A665-Q667 VanDerWaalsContact O-N 3.16Å; A665-G668 PolarHBondContact O-N 3.31Å
666Q97.4Very high95.9Very high1 Ų139.4 Ų39.41%0.00523%0.23CC..G310 helixtrans-61.1-17.8175.6-65.2172.390.300114I532 A548 I552 T575 M576 L662 G663 H664 G668I532-Q666 HydrophobicContact CD1-CB 4.19Å; A548-Q666 WeakPolarHBondContact CA-O 3.28Å; A548-Q666 WeakPolarHBondContact CB-O 3.37Å; I552-Q666 HydrophobicContact CD1-CG 4.32Å; I552-Q666 HydrophobicContact CG1-CG 3.83Å; T575-Q666 VanDerWaalsContact CA-OE1 3.26Å; M576-Q666 VanDerWaalsContact CG-NE2 3.26Å; M576-Q666 HydrophobicContact SD-CB 4.47Å; L662-Q666 HydrophobicContact CB-CG 3.86Å; L662-Q666 HydrophobicContact CD1-CG 4.32Å; G663-Q666 WeakPolarHBondContact O-CB 3.45Å; G663-Q666 WeakPolarHBondContact O-CG 3.48Å; G663-Q666 PolarHBondContact O-N 2.87Å; G663-Q666 PolarHBondContact O-NE2 3.31Å; H664-Q666 PolarHBondContact O-N 3.45Å; H664-Q666 VanDerWaalsContact O-N 3.08Å; Q666-G668 PolarHBondContact O-N 3.47Å
667Q96.1Very high96Very high39 Ų3938.6 Ų38.618%0.18222%0.223CC..G310 helixtrans-69.3-13.8172.6-68.7179.4-8.800113C416 I532 H664 A665C416-Q667 PolarHBondContact SG-O 3.01Å; I532-Q667 HydrophobicContact CD1-CG 4.22Å; H664-Q667 WeakPolarHBondContact O-CB 3.3Å; H664-Q667 PolarHBondContact O-N 2.84Å; A665-Q667 PolarHBondContact O-N 3.36Å; A665-Q667 VanDerWaalsContact O-N 3.16Å
668G94.2Very high96Very high29 Ų2939.3 Ų39.330%0.29923%0.227SC..  trans79.3179.2-179.600000113.8A665 Q666A665-G668 PolarHBondContact O-N 3.31Å; Q666-G668 PolarHBondContact O-N 3.47Å
669G92.3Very high96Very high51 Ų5133.4 Ų33.453%0.52620%0.204SC..SBendtrans-109.5-90.9172.100000109.2G466G466-G669 WeakPolarHBondContact CA-O 3.28Å; G466-G669 PolarHBondContact N-O 3.39Å
670N94.5Very high96Very high80 Ų8030.7 Ų30.743%0.42819%0.191SC..BIsolated β-bridgetrans-80.6145.1168.9-68.2-5.4000110.1D185 R464D185-N670 PolarHBondContact OD2-ND2 3.01Å; R464-N670 WeakPolarHBondContact O-CA 3.3Å; R464-N670 WeakPolarHBondContact O-CB 3.17Å
671A96.1Very high95.8Very high3 Ų332.7 Ų32.73%0.02519%0.194CC..PPolyproline II helixtrans-66.8144.3178.500000111.1C416 R464 R676C416-A671 HydrophobicContact CB-CB 3.73Å; R464-A671 PolarHBondContact O-N 3.35Å; R464-A671 VanDerWaalsContact O-N 3.11Å; A671-R676 HydrophobicContact CB-CG 3.76Å; A671-R676 PolarHBondContact O-NE 3.3Å; A671-R676 PolarHBondContact O-NH2 3.48Å
672S97.3Very high95.7Very high8 Ų829.1 Ų29.16%0.05617%0.172CC..PPolyproline II helixtrans-64.9156.9172.274.90000111.4D546 T547 F674 D675 R676D546-S672 WeakPolarHBondContact OD2-CB 3.4Å; D546-S672 PolarHBondContact OD2-OG 3.11Å; T547-S672 PolarHBondContact OG1-N 2.81Å; T547-S672 PolarHBondContact OG1-OG 2.98Å; S672-F674 PolarHBondContact O-N 3.36Å; S672-D675 PolarHBondContact O-N 3.28Å; S672-D675 PolarHBondContact OG-N 3.49Å; S672-R676 VanDerWaalsContact O-CG 3.29Å; S672-R676 WeakPolarHBondContact O-CG 3.47Å; S672-R676 PolarHBondContact O-N 2.94Å
673P97Very high95.7Very high3 Ų328.1 Ų28.12%0.01917%0.167CC..Hα-helixtrans-55.5-39.7175-21.230.5000112.4L177 N178 V181 V217 R676 L677L177-P673 HydrophobicContact CB-CB 3.98Å; L177-P673 HydrophobicContact CB-CG 4.11Å; N178-P673 HydrophobicContact CB-CG 4.35Å; N178-P673 VanDerWaalsContact OD1-CD 3.22Å; N178-P673 WeakPolarHBondContact OD1-CD 3.5Å; V181-P673 HydrophobicContact CB-CG 4.06Å; V181-P673 HydrophobicContact CG2-CB 4.16Å; V181-P673 HydrophobicContact CG2-CG 3.86Å; V217-P673 HydrophobicContact CG2-CB 4.49Å; P673-R676 PolarHBondContact O-N 3.34Å; P673-L677 WeakPolarHBondContact O-CB 3.47Å; P673-L677 PolarHBondContact O-N 2.91Å
674F95.6Very high95.6Very high30 Ų3028.2 Ų28.213%0.13216%0.162CC..Hα-helixtrans-59.3-50.7177.3-172.1-84.7000111.5F303 D546 S672 R676 L677 M678F303-F674 HydrophobicContact CD2-CD2 4.16Å; F303-F674 AromaticContact CD2-CE2 4Å; F303-F674 HydrophobicContact CD2-CE2 4Å; F303-F674 HydrophobicContact CE2-CD2 4.31Å; F303-F674 AromaticContact CE2-CE2 3.78Å; F303-F674 HydrophobicContact CE2-CE2 3.78Å; D546-F674 HydrophobicContact CB-CB 4.2Å; D546-F674 HydrophobicContact CB-CD1 3.75Å; D546-F674 HydrophobicContact CB-CG 4.22Å; S672-F674 PolarHBondContact O-N 3.36Å; F674-R676 PolarHBondContact O-N 3Å; F674-L677 PolarHBondContact O-N 3.46Å; F674-M678 HydrophobicContact CE1-CB 4.49Å; F674-M678 HydrophobicContact CE1-SD 3.86Å; F674-M678 VanDerWaalsContact O-CB 3.28Å; F674-M678 WeakPolarHBondContact O-CB 3.47Å; F674-M678 PolarHBondContact O-N 2.9Å
675D97.2Very high95.6Very high0 Ų024.9 Ų24.90%015%0.147CC..Hα-helixtrans-66.5-38.2-180-79-37.5000112.3I543 G544 T547 S672 A679I543-D675 HydrophobicContact CG2-CB 4.42Å; G544-D675 VanDerWaalsContact C-OD2 3.29Å; G544-D675 VanDerWaalsContact CA-CG 3.45Å; G544-D675 WeakPolarHBondContact CA-OD2 3.34Å; G544-D675 PolarHBondContact N-OD1 2.94Å; G544-D675 PolarHBondContact N-OD2 3.04Å; T547-D675 VanDerWaalsContact CB-OD2 3.23Å; T547-D675 WeakPolarHBondContact CB-OD2 3.29Å; T547-D675 PolarHBondContact N-OD2 3.37Å; T547-D675 PolarHBondContact OG1-OD2 3.38Å; S672-D675 PolarHBondContact O-N 3.28Å; S672-D675 PolarHBondContact OG-N 3.49Å; D675-A679 WeakPolarHBondContact O-CB 3.47Å; D675-A679 PolarHBondContact O-N 3.4Å
676R97.1Very high95.6Very high4 Ų422.6 Ų22.62%0.01513%0.128CC..Hα-helixtrans-60.5-46.2174.2-68-179.1-158.2-1647.7111.2V181 D185 V217 T463 A671 S672 P673 F674 T680V181-R676 VanDerWaalsContact CG1-NH1 3.29Å; D185-R676 IonicContact OD1-NH1 2.65Å; D185-R676 PolarHBondContact OD1-NH1 3.18Å; D185-R676 IonicContact OD1-NH2 3.04Å; D185-R676 IonicContact OD2-CZ 2.7Å; D185-R676 IonicContact OD2-NH1 2.98Å; D185-R676 IonicContact OD2-NH2 3.12Å; D185-R676 PolarHBondContact OD2-NH2 2.71Å; V217-R676 HydrophobicContact CB-CB 3.75Å; V217-R676 HydrophobicContact CG1-CB 3.85Å; V217-R676 VanDerWaalsContact O-CD 3.23Å; V217-R676 WeakPolarHBondContact O-CD 2.94Å; V217-R676 PolarHBondContact O-NH1 3.43Å; T463-R676 HydrophobicContact CG2-CB 4Å; T463-R676 HydrophobicContact CG2-CG 4.08Å; A671-R676 HydrophobicContact CB-CG 3.76Å; A671-R676 PolarHBondContact O-NE 3.3Å; A671-R676 PolarHBondContact O-NH2 3.48Å; S672-R676 VanDerWaalsContact O-CG 3.29Å; S672-R676 WeakPolarHBondContact O-CG 3.47Å; S672-R676 PolarHBondContact O-N 2.94Å; P673-R676 PolarHBondContact O-N 3.34Å; F674-R676 PolarHBondContact O-N 3Å; R676-T680 WeakPolarHBondContact O-CB 3.43Å; R676-T680 PolarHBondContact O-N 2.89Å; R676-T680 VanDerWaalsContact O-N 3.09Å; R676-T680 PolarHBondContact O-OG1 3Å
677L95.2Very high95.6Very high18 Ų1822.6 Ų22.69%0.09413%0.128CC..Hα-helixtrans-68.8-45.5-179.5-17863.3000111.5I213 I216 V217 P673 F674 T680 R681I213-L677 HydrophobicContact CD1-CD1 4.26Å; I213-L677 HydrophobicContact CD1-CD2 3.94Å; I213-L677 HydrophobicContact CG2-CD2 3.98Å; I216-L677 HydrophobicContact CD1-CD1 4.34Å; I216-L677 HydrophobicContact CG2-CD1 4.09Å; V217-L677 HydrophobicContact CG1-CB 3.79Å; V217-L677 HydrophobicContact CG1-CD1 4.47Å; P673-L677 WeakPolarHBondContact O-CB 3.47Å; P673-L677 PolarHBondContact O-N 2.91Å; F674-L677 PolarHBondContact O-N 3.46Å; L677-T680 PolarHBondContact O-N 3.13Å; L677-R681 HydrophobicContact CD1-CG 4.3Å; L677-R681 WeakPolarHBondContact O-CG 3.27Å; L677-R681 PolarHBondContact O-N 2.95Å
678M94.4Very high95.5Very high16 Ų1623.8 Ų23.88%0.07913%0.133CC..Hα-helixtrans-61-47.7178.9-176.9169177.300110.8Y541 I543 F674 T680 R681 M682 V717Y541-M678 WeakPolarHBondContact O-CE 3.21Å; I543-M678 HydrophobicContact CG1-CB 4.48Å; I543-M678 HydrophobicContact CG1-CG 3.99Å; I543-M678 HydrophobicContact CG1-SD 4.39Å; F674-M678 HydrophobicContact CE1-CB 4.49Å; F674-M678 HydrophobicContact CE1-SD 3.86Å; F674-M678 VanDerWaalsContact O-CB 3.28Å; F674-M678 WeakPolarHBondContact O-CB 3.47Å; F674-M678 PolarHBondContact O-N 2.9Å; M678-T680 VanDerWaalsContact C-N 3.31Å; M678-T680 PolarHBondContact O-N 3.06Å; M678-R681 PolarHBondContact O-N 3.14Å; M678-M682 HydrophobicContact CE-CE 4.34Å; M678-M682 HydrophobicContact CE-SD 3.38Å; M678-M682 WeakPolarHBondContact CE-SD 3.18Å; M678-M682 HydrophobicContact CG-CG 4.33Å; M678-M682 HydrophobicContact CG-SD 3.74Å; M678-M682 WeakPolarHBondContact O-CB 3.37Å; M678-M682 VanDerWaalsContact O-CG 3.28Å; M678-M682 WeakPolarHBondContact O-CG 3.22Å; M678-M682 PolarHBondContact O-N 3.45Å; M678-M682 HydrophobicContact SD-SD 4.43Å; M678-V717 HydrophobicContact CE-CB 4.48Å; M678-V717 HydrophobicContact CE-CG2 3.78Å
679A96.8Very high95.6Very high0 Ų023.4 Ų23.40%013%0.125CC..Hα-helixtrans-57.1-44.7175.600000112.5G417 A420 A421 I543 D675 A683G417-A679 WeakPolarHBondContact O-CB 3.2Å; A420-A679 HydrophobicContact CB-CB 3.79Å; A421-A679 HydrophobicContact CB-CB 4.13Å; I543-A679 HydrophobicContact CD1-CB 3.85Å; I543-A679 HydrophobicContact CG1-CB 4.32Å; I543-A679 HydrophobicContact CG2-CB 3.95Å; D675-A679 WeakPolarHBondContact O-CB 3.47Å; D675-A679 PolarHBondContact O-N 3.4Å; A679-A683 WeakPolarHBondContact O-CB 3.41Å; A679-A683 PolarHBondContact O-N 2.97Å
680T95.2Very high95.9Very high0 Ų021 Ų210%010%0.1CC..Hα-helixtrans-61.1-53177.2-59.50000110.8I216 L386 C424 R676 L677 M678 M682 A683 I684I216-T680 HydrophobicContact CG2-CG2 3.94Å; L386-T680 HydrophobicContact CD1-CG2 3.41Å; L386-T680 VanDerWaalsContact CD1-CG2 3.41Å; C424-T680 HydrophobicContact CB-CG2 4.43Å; C424-T680 PolarHBondContact SG-O 2.99Å; C424-T680 VanDerWaalsContact SG-O 3.34Å; R676-T680 WeakPolarHBondContact O-CB 3.43Å; R676-T680 PolarHBondContact O-N 2.89Å; R676-T680 VanDerWaalsContact O-N 3.09Å; R676-T680 PolarHBondContact O-OG1 3Å; L677-T680 PolarHBondContact O-N 3.13Å; M678-T680 VanDerWaalsContact C-N 3.31Å; M678-T680 PolarHBondContact O-N 3.06Å; T680-M682 PolarHBondContact O-N 3.31Å; T680-A683 PolarHBondContact O-N 3.48Å; T680-I684 HydrophobicContact CG2-CD1 4.29Å; T680-I684 WeakPolarHBondContact O-CG1 3.4Å; T680-I684 PolarHBondContact O-N 3.31Å
681R93.3Very high95.9Very high95 Ų9517.2 Ų17.236%0.3588%0.08SC..Hα-helixtrans-61.6-42.9-177.5-73.3176.961.2-178.4-1.8112.6L677 M678 I684 H685L677-R681 HydrophobicContact CD1-CG 4.3Å; L677-R681 WeakPolarHBondContact O-CG 3.27Å; L677-R681 PolarHBondContact O-N 2.95Å; M678-R681 PolarHBondContact O-N 3.14Å; R681-I684 PolarHBondContact O-N 3.46Å; R681-H685 PolarHBondContact O-N 3.13Å
682M95.3Very high95.9Very high8 Ų818.8 Ų18.84%0.0399%0.091CC..Hα-helixtrans-65.7-43.8179-69.3-179.58000111.2I528 I543 M678 T680 I684 H685 V686 L715I528-M682 HydrophobicContact CD1-CB 4.27Å; I528-M682 HydrophobicContact CG2-CB 4.34Å; I528-M682 HydrophobicContact CG2-CE 4.2Å; I528-M682 HydrophobicContact CG2-SD 4.43Å; I543-M682 HydrophobicContact CD1-SD 3.91Å; I543-M682 HydrophobicContact CG1-SD 4.06Å; M678-M682 HydrophobicContact CE-CE 4.34Å; M678-M682 HydrophobicContact CE-SD 3.38Å; M678-M682 WeakPolarHBondContact CE-SD 3.18Å; M678-M682 HydrophobicContact CG-CG 4.33Å; M678-M682 HydrophobicContact CG-SD 3.74Å; M678-M682 WeakPolarHBondContact O-CB 3.37Å; M678-M682 VanDerWaalsContact O-CG 3.28Å; M678-M682 WeakPolarHBondContact O-CG 3.22Å; M678-M682 PolarHBondContact O-N 3.45Å; M678-M682 HydrophobicContact SD-SD 4.43Å; T680-M682 PolarHBondContact O-N 3.31Å; M682-I684 PolarHBondContact O-N 3.45Å; M682-H685 PolarHBondContact O-N 3.07Å; M682-V686 WeakPolarHBondContact O-CG2 3.34Å; M682-V686 PolarHBondContact O-N 2.9Å; M682-L715 HydrophobicContact CB-CD2 3.88Å; M682-L715 HydrophobicContact CE-CB 4.38Å; M682-L715 HydrophobicContact CE-CD2 4.29Å; M682-L715 HydrophobicContact CE-CG 4.05Å; M682-L715 WeakPolarHBondContact CE-O 3.27Å; M682-L715 HydrophobicContact CG-CD2 4.11Å; M682-L715 WeakPolarHBondContact O-CD2 3.4Å
683A96.7Very high95.9Very high0 Ų020.1 Ų20.10%010%0.097CC..Hα-helixtrans-65.1-37.2178.400000113.2A421 C424 F425 I528 A679 T680 A687A421-A683 HydrophobicContact CB-CB 4.39Å; A421-A683 VanDerWaalsContact O-CB 3.27Å; A421-A683 WeakPolarHBondContact O-CB 3.43Å; C424-A683 HydrophobicContact CB-CB 3.66Å; F425-A683 HydrophobicContact CB-CB 4.43Å; I528-A683 HydrophobicContact CD1-CB 4.22Å; A679-A683 WeakPolarHBondContact O-CB 3.41Å; A679-A683 PolarHBondContact O-N 2.97Å; T680-A683 PolarHBondContact O-N 3.48Å; A683-A687 VanDerWaalsContact O-CB 3.25Å; A683-A687 WeakPolarHBondContact O-CB 3.44Å; A683-A687 PolarHBondContact O-N 3.04Å
684I94.5Very high95.9Very high23 Ų2320 Ų2012%0.11810%0.096CC..Hα-helixtrans-57-52.8171.6-65.9175.6000110.2A382 L386 C424 M428 T680 R681 M682 V686 A687 Q688A382-I684 HydrophobicContact CB-CD1 3.48Å; A382-I684 VanDerWaalsContact CB-CD1 3.48Å; L386-I684 HydrophobicContact CD1-CD1 4.08Å; C424-I684 WeakPolarHBondContact SG-CG1 3.29Å; M428-I684 HydrophobicContact CE-CG2 4.07Å; M428-I684 HydrophobicContact CG-CG1 4.15Å; M428-I684 HydrophobicContact SD-CG1 4.18Å; M428-I684 HydrophobicContact SD-CG2 4.23Å; T680-I684 HydrophobicContact CG2-CD1 4.29Å; T680-I684 WeakPolarHBondContact O-CG1 3.4Å; T680-I684 PolarHBondContact O-N 3.31Å; R681-I684 PolarHBondContact O-N 3.46Å; M682-I684 PolarHBondContact O-N 3.45Å; I684-V686 PolarHBondContact O-N 3.45Å; I684-A687 PolarHBondContact O-N 3.03Å; I684-Q688 WeakPolarHBondContact O-CG 3.36Å; I684-Q688 PolarHBondContact O-N 3Å; I684-Q688 VanDerWaalsContact O-N 3.11Å
685H94.6Very high95.8Very high67 Ų6724.4 Ų24.431%0.3111%0.112SC..Hα-helixtrans-62.7-47.3-175.6-170.463.2000111.6R681 M682 A687 Q688 V689 L715R681-H685 PolarHBondContact O-N 3.13Å; M682-H685 PolarHBondContact O-N 3.07Å; H685-A687 PolarHBondContact O-N 2.82Å; H685-Q688 PolarHBondContact O-N 3.25Å; H685-V689 WeakPolarHBondContact O-CG2 3.48Å; H685-V689 PolarHBondContact O-N 3.05Å; H685-L715 HydrophobicContact CB-CD2 4.05Å
686V97.1Very high95.7Very high0 Ų031.8 Ų31.80%015%0.146CC..Hα-helixtrans-62.9-42.1178.5171.90000112.1L497 A526 I528 M682 I684 Q688 V689 L690 L715L497-V686 HydrophobicContact CD1-CG1 3.72Å; A526-V686 HydrophobicContact CB-CG1 3.4Å; A526-V686 VanDerWaalsContact CB-CG1 3.4Å; A526-V686 HydrophobicContact CB-CG2 4.49Å; I528-V686 HydrophobicContact CD1-CB 4.13Å; I528-V686 HydrophobicContact CD1-CG2 3.87Å; I528-V686 HydrophobicContact CG1-CB 4.44Å; I528-V686 HydrophobicContact CG1-CG2 3.73Å; M682-V686 WeakPolarHBondContact O-CG2 3.34Å; M682-V686 PolarHBondContact O-N 2.9Å; I684-V686 PolarHBondContact O-N 3.45Å; V686-Q688 VanDerWaalsContact C-N 3.33Å; V686-Q688 PolarHBondContact O-N 3.46Å; V686-V689 PolarHBondContact O-N 3.45Å; V686-L690 HydrophobicContact CG1-CD1 3.87Å; V686-L690 HydrophobicContact CG1-CG 4.05Å; V686-L690 WeakPolarHBondContact O-CB 3.22Å; V686-L690 WeakPolarHBondContact O-CG 3.31Å; V686-L690 PolarHBondContact O-N 2.82Å; V686-L715 HydrophobicContact CG2-CB 3.72Å; V686-L715 HydrophobicContact CG2-CD2 3.49Å; V686-L715 VanDerWaalsContact CG2-CD2 3.49Å; V686-L715 HydrophobicContact CG2-CG 4.22Å
687A96.5Very high95.7Very high0 Ų033.7 Ų33.70%016%0.158CC..Hα-helixtrans-59.7-45.5178.200000111.6F425 M428 A683 I684 H685 V691F425-A687 HydrophobicContact CD2-CB 3.68Å; F425-A687 HydrophobicContact CE2-CB 3.98Å; M428-A687 HydrophobicContact CB-CB 3.35Å; M428-A687 HydrophobicContact CG-CB 4.19Å; A683-A687 VanDerWaalsContact O-CB 3.25Å; A683-A687 WeakPolarHBondContact O-CB 3.44Å; A683-A687 PolarHBondContact O-N 3.04Å; I684-A687 PolarHBondContact O-N 3.03Å; H685-A687 PolarHBondContact O-N 2.82Å; A687-V691 WeakPolarHBondContact O-CB 3.27Å; A687-V691 VanDerWaalsContact O-CG2 3.25Å; A687-V691 WeakPolarHBondContact O-CG2 3.39Å; A687-V691 PolarHBondContact O-N 3.31Å
688Q94.8Very high95.6Very high65 Ų6534.1 Ų34.130%0.30416%0.164SC..Hα-helixtrans-62.7-44.4177.5-69.8174.2-30.500111.6L398 M428 I684 H685 V686 V691 S692L398-Q688 HydrophobicContact CD1-CB 3.74Å; L398-Q688 HydrophobicContact CD1-CG 3.79Å; M428-Q688 HydrophobicContact CE-CG 3.83Å; I684-Q688 WeakPolarHBondContact O-CG 3.36Å; I684-Q688 PolarHBondContact O-N 3Å; I684-Q688 VanDerWaalsContact O-N 3.11Å; H685-Q688 PolarHBondContact O-N 3.25Å; V686-Q688 VanDerWaalsContact C-N 3.33Å; V686-Q688 PolarHBondContact O-N 3.46Å; Q688-V691 PolarHBondContact O-N 2.87Å; Q688-S692 WeakPolarHBondContact O-CB 3.3Å; Q688-S692 PolarHBondContact O-N 3.36Å; Q688-S692 PolarHBondContact O-OG 3.07Å; Q688-S692 VanDerWaalsContact O-OG 3.07Å
689V96.5Very high95.5Very high21 Ų2135.8 Ų35.813%0.12718%0.18CC..Hα-helixtrans-62.1-49178.9169.80000111.2H685 V686 V691 S692 M693 L713 L724H685-V689 WeakPolarHBondContact O-CG2 3.48Å; H685-V689 PolarHBondContact O-N 3.05Å; V686-V689 PolarHBondContact O-N 3.45Å; V689-V691 VanDerWaalsContact C-N 3.34Å; V689-V691 PolarHBondContact O-N 3Å; V689-S692 PolarHBondContact O-N 3.34Å; V689-M693 HydrophobicContact CG1-CE 4Å; V689-M693 HydrophobicContact CG1-CG 4.39Å; V689-M693 HydrophobicContact CG1-SD 3.97Å; V689-M693 WeakPolarHBondContact O-CB 3.5Å; V689-M693 WeakPolarHBondContact O-CG 3.36Å; V689-M693 PolarHBondContact O-N 2.76Å; V689-L713 HydrophobicContact CG1-CD1 4.25Å; V689-L724 HydrophobicContact CB-CD1 4.37Å; V689-L724 HydrophobicContact CG1-CD1 3.87Å; V689-L724 HydrophobicContact CG2-CD1 3.65Å
690L97.8Very high94.9Very high1 Ų145.6 Ų45.61%0.00523%0.226CC..Hα-helixtrans-63-39.9-179.9-72.7-176.8000112F425 A495 L497 P524 A526 V686 A694F425-L690 HydrophobicContact CE2-CD1 3.92Å; F425-L690 HydrophobicContact CZ-CD1 4.08Å; A495-L690 HydrophobicContact CB-CB 4.13Å; A495-L690 HydrophobicContact CB-CD1 4.39Å; A495-L690 HydrophobicContact CB-CD2 4.37Å; L497-L690 HydrophobicContact CB-CD1 4.31Å; P524-L690 HydrophobicContact CB-CD2 3.82Å; A526-L690 HydrophobicContact CB-CD1 4.05Å; A526-L690 HydrophobicContact CB-CD2 3.89Å; A526-L690 HydrophobicContact CB-CG 4.08Å; V686-L690 HydrophobicContact CG1-CD1 3.87Å; V686-L690 HydrophobicContact CG1-CG 4.05Å; V686-L690 WeakPolarHBondContact O-CB 3.22Å; V686-L690 WeakPolarHBondContact O-CG 3.31Å; V686-L690 PolarHBondContact O-N 2.82Å; L690-A694 WeakPolarHBondContact O-CB 3.31Å; L690-A694 PolarHBondContact O-N 3.43Å
691V95.9Very high94.4Very high0 Ų051.8 Ų51.80%026%0.259CS..Hα-helixtrans-65.9-44.6176.3171.90000111.3L398 L406 H432 A687 Q688 V689 A694 R695L398-V691 HydrophobicContact CB-CG1 3.85Å; L406-V691 HydrophobicContact CD1-CG2 3.94Å; H432-V691 HydrophobicContact CB-CG1 4.07Å; H432-V691 HydrophobicContact CB-CG2 4.23Å; A687-V691 WeakPolarHBondContact O-CB 3.27Å; A687-V691 VanDerWaalsContact O-CG2 3.25Å; A687-V691 WeakPolarHBondContact O-CG2 3.39Å; A687-V691 PolarHBondContact O-N 3.31Å; Q688-V691 PolarHBondContact O-N 2.87Å; V689-V691 VanDerWaalsContact C-N 3.34Å; V689-V691 PolarHBondContact O-N 3Å; V691-A694 PolarHBondContact O-N 2.87Å; V691-R695 WeakPolarHBondContact O-CB 3.41Å; V691-R695 PolarHBondContact O-N 2.84Å
692S96Very high93.9Very high36 Ų3648.1 Ų48.125%0.25225%0.251SS..Hα-helixtrans-62.8-46.6177.5-65.10000111.6Q688 V689 A694 R695 E696Q688-S692 WeakPolarHBondContact O-CB 3.3Å; Q688-S692 PolarHBondContact O-N 3.36Å; Q688-S692 PolarHBondContact O-OG 3.07Å; Q688-S692 VanDerWaalsContact O-OG 3.07Å; V689-S692 PolarHBondContact O-N 3.34Å; S692-A694 PolarHBondContact O-N 3.42Å; S692-R695 WeakPolarHBondContact O-CB 3.23Å; S692-R695 PolarHBondContact O-N 3.44Å; S692-E696 WeakPolarHBondContact O-CG 3.4Å; S692-E696 PolarHBondContact O-N 3.07Å
693M96.7Very high93.7Very high36 Ų3650.2 Ų50.218%0.17727%0.267CS..Hα-helixtrans-61.7-44.4176.7-74.4-175.316700112.1P524 V689 R695 E696 V697 L713P524-M693 HydrophobicContact CB-CB 4Å; P524-M693 HydrophobicContact CB-SD 4.46Å; P524-M693 HydrophobicContact CG-CB 3.84Å; V689-M693 HydrophobicContact CG1-CE 4Å; V689-M693 HydrophobicContact CG1-CG 4.39Å; V689-M693 HydrophobicContact CG1-SD 3.97Å; V689-M693 WeakPolarHBondContact O-CB 3.5Å; V689-M693 WeakPolarHBondContact O-CG 3.36Å; V689-M693 PolarHBondContact O-N 2.76Å; M693-R695 VanDerWaalsContact C-N 3.26Å; M693-R695 PolarHBondContact O-N 3.05Å; M693-E696 PolarHBondContact O-N 3.3Å; M693-V697 WeakPolarHBondContact O-CG2 3.33Å; M693-V697 PolarHBondContact O-N 2.94Å; M693-V697 VanDerWaalsContact O-N 3.16Å; M693-L713 HydrophobicContact CE-CD1 3.3Å; M693-L713 HydrophobicContact CE-CG 4.47Å; M693-L713 HydrophobicContact SD-CD1 3.95Å
694A96.4Very high93.6Very high0 Ų051 Ų510%027%0.271CS..Hα-helixtrans-59.1-40.3177.100000111.2F404 L690 V691 S692 A698 V704F404-A694 HydrophobicContact CD1-CB 4.21Å; F404-A694 HydrophobicContact CD2-CB 4.11Å; F404-A694 HydrophobicContact CE1-CB 4.24Å; F404-A694 HydrophobicContact CE2-CB 4.14Å; F404-A694 HydrophobicContact CG-CB 4.15Å; F404-A694 HydrophobicContact CZ-CB 4.21Å; L690-A694 WeakPolarHBondContact O-CB 3.31Å; L690-A694 PolarHBondContact O-N 3.43Å; V691-A694 PolarHBondContact O-N 2.87Å; S692-A694 PolarHBondContact O-N 3.42Å; A694-A698 VanDerWaalsContact O-CB 3.3Å; A694-A698 WeakPolarHBondContact O-CB 3.48Å; A694-A698 PolarHBondContact O-N 2.78Å; A694-V704 HydrophobicContact CB-CG1 4.41Å; A694-V704 HydrophobicContact CB-CG2 4.21Å
695R94.7Very high93.8Very high123 Ų12356.1 Ų56.146%0.46429%0.29SS..Hα-helixtrans-67.5-43175.6178.1178174.7-173.5-1.7113.2L398 L402 F404 V691 S692 M693 V697 A698L398-R695 WeakPolarHBondContact O-CD 3.27Å; L398-R695 PolarHBondContact O-NH1 3.29Å; L402-R695 HydrophobicContact CD1-CG 4.45Å; F404-R695 HydrophobicContact CE2-CB 4.09Å; F404-R695 HydrophobicContact CZ-CB 4.1Å; V691-R695 WeakPolarHBondContact O-CB 3.41Å; V691-R695 PolarHBondContact O-N 2.84Å; S692-R695 WeakPolarHBondContact O-CB 3.23Å; S692-R695 PolarHBondContact O-N 3.44Å; M693-R695 VanDerWaalsContact C-N 3.26Å; M693-R695 PolarHBondContact O-N 3.05Å; R695-V697 PolarHBondContact O-N 3.11Å; R695-A698 PolarHBondContact O-N 3.05Å
696E95.2Very high93.9Very high154 Ų15453.4 Ų53.472%0.7228%0.278SS*.Hα-helixtrans-62.2-32.7-179.4-76.3171.6-17100112.5S692 M693S692-E696 WeakPolarHBondContact O-CG 3.4Å; S692-E696 PolarHBondContact O-N 3.07Å; M693-E696 PolarHBondContact O-N 3.3Å
697V95.6Very high93.8Very high45 Ų4558.2 Ų58.227%0.27330%0.304SS..THydrogen-bonded Turntrans-106.311.4-178.9-48.30000113.3M693 R695 V704 T706M693-V697 WeakPolarHBondContact O-CG2 3.33Å; M693-V697 PolarHBondContact O-N 2.94Å; M693-V697 VanDerWaalsContact O-N 3.16Å; R695-V697 PolarHBondContact O-N 3.11Å; V697-V704 HydrophobicContact CG2-CG1 3.56Å; V697-T706 HydrophobicContact CG2-CG2 4.07Å
698A94.2Very high93.7Very high27 Ų2761.7 Ų61.722%0.22332%0.323CS..BIsolated β-bridgetrans-74.6134.7177.100000111L402 F404 A694 R695 S703 V704L402-A698 HydrophobicContact CD1-CB 3.91Å; F404-A698 HydrophobicContact CE1-CB 4.07Å; F404-A698 HydrophobicContact CZ-CB 4.19Å; A694-A698 VanDerWaalsContact O-CB 3.3Å; A694-A698 WeakPolarHBondContact O-CB 3.48Å; A694-A698 PolarHBondContact O-N 2.78Å; R695-A698 PolarHBondContact O-N 3.05Å; A698-S703 CarbonylContact C-O 3.48Å; A698-S703 WeakPolarHBondContact CA-O 3.36Å; A698-V704 HydrophobicContact CB-CG2 4.41Å
699A91.5Very high93.6Very high50 Ų5061.5 Ų61.541%0.41333%0.327SS..  trans-76.7171.6166.400000111.2D701 G702 S703A699-D701 WeakPolarHBondContact CB-OD1 3.09Å; A699-D701 PolarHBondContact O-N 2.83Å; A699-G702 PolarHBondContact O-N 3.39Å; A699-S703 PolarHBondContact N-O 2.98Å
700E84.2Confident93.6Very high207 Ų20764.9 Ų64.997%0.96734%0.344SS*.THydrogen-bonded Turntrans-59.6-29-179.6-65.9-175.517100113.5G702E700-G702 PolarHBondContact O-N 3.16Å
701D85Confident93.6Very high129 Ų12965.4 Ų65.469%0.6935%0.347SS*.THydrogen-bonded Turntrans-81.3-0.7176.773.5-15.3000113.5A699 S703A699-D701 WeakPolarHBondContact CB-OD1 3.09Å; A699-D701 PolarHBondContact O-N 2.83Å; D701-S703 VanDerWaalsContact C-N 3.29Å; D701-S703 WeakPolarHBondContact OD1-CB 3.24Å; D701-S703 PolarHBondContact OD1-N 3.48Å; D701-S703 PolarHBondContact OD1-OG 3.4Å; D701-S703 PolarHBondContact OD2-OG 3.14Å
702G83.8Confident93.7Very high19 Ų1965.4 Ų65.420%0.19635%0.347CS..SBendtrans79.93.4-176.600000114.4A699 E700A699-G702 PolarHBondContact O-N 3.39Å; E700-G702 PolarHBondContact O-N 3.16Å
703S90.3Very high93.8Very high52 Ų5264.1 Ų64.136%0.36434%0.338SS..  trans-67.8143.9169.867.50000110.3A698 A699 D701A698-S703 CarbonylContact C-O 3.48Å; A698-S703 WeakPolarHBondContact CA-O 3.36Å; A699-S703 PolarHBondContact N-O 2.98Å; D701-S703 VanDerWaalsContact C-N 3.29Å; D701-S703 WeakPolarHBondContact OD1-CB 3.24Å; D701-S703 PolarHBondContact OD1-N 3.48Å; D701-S703 PolarHBondContact OD1-OG 3.4Å; D701-S703 PolarHBondContact OD2-OG 3.14Å
704V95.3Very high93.8Very high15 Ų1562.4 Ų62.49%0.09133%0.33CS..BIsolated β-bridgetrans-113.9126.3-176.8174.80000107.4F404 N494 P524 A694 V697 A698F404-V704 HydrophobicContact CD1-CG2 3.79Å; F404-V704 HydrophobicContact CE1-CG2 3.66Å; N494-V704 HydrophobicContact CB-CB 4.14Å; N494-V704 HydrophobicContact CB-CG2 3.86Å; P524-V704 HydrophobicContact CG-CG1 4.37Å; A694-V704 HydrophobicContact CB-CG1 4.41Å; A694-V704 HydrophobicContact CB-CG2 4.21Å; V697-V704 HydrophobicContact CG2-CG1 3.56Å; A698-V704 HydrophobicContact CB-CG2 4.41Å
705Y97.1Very high93.8Very high131 Ų13162.5 Ų62.551%0.51433%0.33SS..  trans-141.9125.2177-178.6-87.5000110.8K519 C522K519-Y705 HydrophobicContact CB-CE2 4.41Å; C522-Y705 HydrophobicContact CB-CD2 3.63Å; C522-Y705 HydrophobicContact CB-CE2 3.48Å; C522-Y705 VanDerWaalsContact CB-CE2 3.48Å; C522-Y705 HydrophobicContact CB-CG 4.32Å; C522-Y705 CarbonylContact O-C 3.39Å; C522-Y705 WeakPolarHBondContact O-CA 3.13Å
706T96.5Very high93.7Very high11 Ų1156.6 Ų56.67%0.06731%0.308CS..  trans-153.8124172.6-177.90000111C522 P524 V697 T711C522-T706 CarbonylContact C-O 3.43Å; C522-T706 WeakPolarHBondContact CA-O 3.32Å; C522-T706 WeakPolarHBondContact CB-O 3.36Å; C522-T706 PolarHBondContact O-N 3.06Å; P524-T706 HydrophobicContact CG-CG2 4.14Å; V697-T706 HydrophobicContact CG2-CG2 4.07Å; T706-T711 HydrophobicContact CG2-CG2 3.87Å; T706-T711 WeakPolarHBondContact CG2-OG1 3.38Å; T706-T711 WeakPolarHBondContact OG1-CG2 3.42Å
707D94.8Very high93.3Very high100 Ų10050.6 Ų50.654%0.53528%0.281SS..  trans-94.7-11.9172.159.1-2.2000112.5R515 P709R515-D707 PolarHBondContact NH1-O 2.91Å; R515-D707 VanDerWaalsContact NH1-O 3.13Å; D707-P709 WeakPolarHBondContact O-CD 3.44Å
708N95.6Very high92.8Very high74 Ų7450 Ų5040%0.39628%0.276SS..  trans-54.5118.7-178.5-175.7-21000111.5R515 N710 T711R515-N708 VanDerWaalsContact NH1-C 3.33Å; R515-N708 PolarHBondContact NH1-O 3.36Å; N708-N710 PolarHBondContact O-N 3.33Å; N708-N710 WeakPolarHBondContact OD1-CB 3.42Å; N708-N710 PolarHBondContact OD1-N 2.86Å; N708-T711 HydrophobicContact CB-CG2 4.33Å; N708-T711 PolarHBondContact O-N 3.18Å; N708-T711 PolarHBondContact O-OG1 2.84Å
709P93.3Very high92Very high60 Ų6054.4 Ų54.439%0.3929%0.292SS..G310 helixtrans-50.7-30.3178.7-31.637.7000115D707 T711 A712 L728D707-P709 WeakPolarHBondContact O-CD 3.44Å; P709-T711 PolarHBondContact O-N 3.34Å; P709-T711 VanDerWaalsContact O-N 3.16Å; P709-A712 PolarHBondContact O-N 3.07Å; P709-A712 VanDerWaalsContact O-N 3.17Å; P709-L728 HydrophobicContact CB-CD1 4.17Å
710N95.5Very high91.3Very high92 Ų9257 Ų5749%0.49229%0.291SS..G310 helixtrans-74.4-0.4-177.3-62.4-18.8000113.8N708 L713 P726N708-N710 PolarHBondContact O-N 3.33Å; N708-N710 WeakPolarHBondContact OD1-CB 3.42Å; N708-N710 PolarHBondContact OD1-N 2.86Å; N710-L713 WeakPolarHBondContact O-CD2 3.49Å; N710-L713 WeakPolarHBondContact O-CG 3.25Å; N710-P726 HydrophobicContact CB-CG 4.38Å; N710-P726 WeakPolarHBondContact OD1-CG 3.38Å
711T97.2Very high91.2Very high12 Ų1253.6 Ų53.67%0.07428%0.275CS..G310 helixtrans-94.6-1.4171.663.30000113.1R515 P524 M525 T706 N708 P709R515-T711 PolarHBondContact NH1-OG1 3.03Å; R515-T711 VanDerWaalsContact NH1-OG1 3.17Å; R515-T711 PolarHBondContact NH2-OG1 3.14Å; P524-T711 WeakPolarHBondContact CA-O 3.33Å; M525-T711 PolarHBondContact N-O 3.01Å; M525-T711 VanDerWaalsContact O-O 3.1Å; T706-T711 HydrophobicContact CG2-CG2 3.87Å; T706-T711 WeakPolarHBondContact CG2-OG1 3.38Å; T706-T711 WeakPolarHBondContact OG1-CG2 3.42Å; N708-T711 HydrophobicContact CB-CG2 4.33Å; N708-T711 PolarHBondContact O-N 3.18Å; N708-T711 PolarHBondContact O-OG1 2.84Å; P709-T711 PolarHBondContact O-N 3.34Å; P709-T711 VanDerWaalsContact O-N 3.16Å
712A98.1Very high91.3Very high0 Ų050.3 Ų50.30%027%0.266CS..EExtended strand (participates in β ladder)trans-107.699.6170.200000109.6T512 M525 P709 P726 V727T512-A712 HydrophobicContact CG2-CB 3.94Å; T512-A712 WeakPolarHBondContact OG1-CB 3.21Å; M525-A712 HydrophobicContact CB-CB 4.43Å; M525-A712 HydrophobicContact CE-CB 4.12Å; M525-A712 CarbonylContact O-C 3.16Å; M525-A712 WeakPolarHBondContact O-CA 3.5Å; P709-A712 PolarHBondContact O-N 3.07Å; P709-A712 VanDerWaalsContact O-N 3.17Å; A712-P726 WeakPolarHBondContact O-CA 3.46Å; A712-V727 HydrophobicContact CB-CG2 3.92Å; A712-V727 PolarHBondContact O-N 3.38Å
713L98Very high91.7Very high10 Ų1053.5 Ų53.55%0.05228%0.275CS..EExtended strand (participates in β ladder)trans-116.1155.2-165.4-64.5170000112.4M525 A526 V527 V689 M693 N710 L724 T725 P726M525-L713 PolarHBondContact O-N 3.01Å; A526-L713 CarbonylContact C-O 3.53Å; A526-L713 VanDerWaalsContact CA-O 3.22Å; A526-L713 WeakPolarHBondContact CA-O 3.36Å; V527-L713 PolarHBondContact N-O 2.67Å; V689-L713 HydrophobicContact CG1-CD1 4.25Å; M693-L713 HydrophobicContact CE-CD1 3.3Å; M693-L713 HydrophobicContact CE-CG 4.47Å; M693-L713 HydrophobicContact SD-CD1 3.95Å; N710-L713 WeakPolarHBondContact O-CD2 3.49Å; N710-L713 WeakPolarHBondContact O-CG 3.25Å; L713-L724 HydrophobicContact CB-CD2 4.2Å; L713-L724 HydrophobicContact CD1-CB 4.12Å; L713-L724 HydrophobicContact CD1-CD1 4.33Å; L713-L724 HydrophobicContact CD1-CD2 4.16Å; L713-L724 HydrophobicContact CD1-CG 4.44Å; L713-L724 HydrophobicContact CD2-CB 4.33Å; L713-T725 CarbonylContact C-O 3.5Å; L713-T725 WeakPolarHBondContact CA-O 3.45Å; L713-P726 HydrophobicContact CD2-CG 4.13Å
714L97.8Very high91.9Very high0 Ų053.5 Ų53.50%027%0.271CS..EExtended strand (participates in β ladder)trans-114.9125.3163.3-177.1144000108.2Y505 V527 P529 V536 P537 A539 G716 L724 T725 V727 L730Y505-L714 HydrophobicContact CD2-CD1 3.8Å; Y505-L714 HydrophobicContact CG-CD1 4.31Å; V527-L714 HydrophobicContact CB-CB 4.33Å; V527-L714 HydrophobicContact CB-CD1 4.21Å; V527-L714 HydrophobicContact CB-CG 4.23Å; V527-L714 HydrophobicContact CG1-CD1 4.1Å; V527-L714 HydrophobicContact CG1-CG 4.48Å; P529-L714 HydrophobicContact CG-CD1 4.12Å; P529-L714 HydrophobicContact CG-CD2 3.81Å; P529-L714 HydrophobicContact CG-CG 3.97Å; V536-L714 HydrophobicContact CG1-CD1 3.65Å; P537-L714 WeakPolarHBondContact O-CD1 3.44Å; P537-L714 WeakPolarHBondContact O-CD2 3.29Å; A539-L714 HydrophobicContact CB-CD2 4.47Å; L714-G716 PolarHBondContact O-N 3.37Å; L714-L724 WeakPolarHBondContact O-CA 3.49Å; L714-T725 PolarHBondContact N-O 3.45Å; L714-T725 PolarHBondContact O-N 3.14Å; L714-V727 HydrophobicContact CB-CG1 4.17Å; L714-L730 HydrophobicContact CB-CD1 3.79Å; L714-L730 HydrophobicContact CD1-CD1 4.1Å; L714-L730 HydrophobicContact CD2-CD1 4.05Å; L714-L730 HydrophobicContact CG-CD1 4.2Å
715L96.7Very high91.9Very high1 Ų152.9 Ų52.91%0.00527%0.268CS..EExtended strand (participates in β ladder)trans-87.7108.2171.9-179.263.2000108.8V527 P529 M682 H685 V686 A722 L724V527-L715 PolarHBondContact O-N 3.06Å; P529-L715 WeakPolarHBondContact CD-O 3.45Å; M682-L715 HydrophobicContact CB-CD2 3.88Å; M682-L715 HydrophobicContact CE-CB 4.38Å; M682-L715 HydrophobicContact CE-CD2 4.29Å; M682-L715 HydrophobicContact CE-CG 4.05Å; M682-L715 WeakPolarHBondContact CE-O 3.27Å; M682-L715 HydrophobicContact CG-CD2 4.11Å; M682-L715 WeakPolarHBondContact O-CD2 3.4Å; H685-L715 HydrophobicContact CB-CD2 4.05Å; V686-L715 HydrophobicContact CG2-CB 3.72Å; V686-L715 HydrophobicContact CG2-CD2 3.49Å; V686-L715 VanDerWaalsContact CG2-CD2 3.49Å; V686-L715 HydrophobicContact CG2-CG 4.22Å; L715-A722 HydrophobicContact CD1-CB 4.11Å; L715-L724 HydrophobicContact CB-CD2 3.86Å; L715-L724 HydrophobicContact CD1-CD2 3.79Å; L715-L724 HydrophobicContact CD1-CG 3.96Å; L715-L724 HydrophobicContact CG-CD2 4.38Å
716G92.3Very high91.9Very high0 Ų047.5 Ų47.50%025%0.248CC..EExtended strand (participates in β ladder)trans-109.5162.3171.500000112.1G538 L714 A722 Q723G538-G716 WeakPolarHBondContact O-CA 3.34Å; L714-G716 PolarHBondContact O-N 3.37Å; G716-A722 CarbonylContact O-C 3.29Å; G716-A722 WeakPolarHBondContact O-CA 3.31Å; G716-Q723 PolarHBondContact N-O 3.38Å; G716-Q723 PolarHBondContact O-N 3.03Å
717V87.2Confident92Very high27 Ų2747 Ų4716%0.16425%0.245CC..EExtended strand (participates in β ladder)trans-97.4108.5161.5-179.90000106.6N540 Y541 M678N540-V717 VanDerWaalsContact CB-O 3.26Å; N540-V717 WeakPolarHBondContact CB-O 3.45Å; N540-V717 PolarHBondContact N-O 2.97Å; Y541-V717 HydrophobicContact CD2-CG1 4.45Å; M678-V717 HydrophobicContact CE-CB 4.48Å; M678-V717 HydrophobicContact CE-CG2 3.78Å
718L83.8Confident92Very high33 Ų3344.4 Ų44.417%0.17323%0.231CC..EExtended strand (participates in β ladder)trans-113.9121.7177.8-72.9172.1000108.7G538 R720 H721 Q723G538-L718 WeakPolarHBondContact O-CD1 3.36Å; G538-L718 VanDerWaalsContact O-CG 3.29Å; G538-L718 WeakPolarHBondContact O-CG 3.23Å; L718-R720 PolarHBondContact O-N 2.88Å; L718-H721 PolarHBondContact N-O 3.4Å; L718-H721 PolarHBondContact O-N 3.26Å; L718-H721 VanDerWaalsContact O-O 3.08Å; L718-Q723 HydrophobicContact CB-CB 4.36Å; L718-Q723 HydrophobicContact CD1-CB 4.18Å; L718-Q723 HydrophobicContact CD1-CG 4.26Å; L718-Q723 VanDerWaalsContact CD1-OE1 3.3Å
719H76.9Confident92.1Very high120 Ų12045 Ų4556%0.55623%0.232SC*.THydrogen-bonded Turntrans48-118.3-172.6-51.5-75.5000110.2G338 V340 N540G338-H719 CarbonylContact O-C 3.54Å; V340-H719 HydrophobicContact CG2-CB 4.34Å; N540-H719 PolarHBondContact ND2-N 3.32Å
720R78.4Confident92.2Very high105 Ų10542.8 Ų42.840%0.39622%0.216SC..THydrogen-bonded Turntrans-88.4-4.8-173.2-49.8-171.8-176.3176.412.2114.5D337 V340 L718D337-R720 WeakPolarHBondContact O-CG 3.46Å; D337-R720 IonicContact OD2-CZ 3.53Å; D337-R720 IonicContact OD2-NE 3.37Å; D337-R720 IonicContact OD2-NH1 2.75Å; D337-R720 PolarHBondContact OD2-NH1 3.37Å; V340-R720 HydrophobicContact CG2-CG 4.33Å; L718-R720 PolarHBondContact O-N 2.88Å
721H81.6Confident92.2Very high134 Ų13441.9 Ų41.962%0.6221%0.208SC*.EExtended strand (participates in β ladder)trans-131.2145.6-165.4-59.1-41.4000112.6L718 Q723L718-H721 PolarHBondContact N-O 3.4Å; L718-H721 PolarHBondContact O-N 3.26Å; L718-H721 VanDerWaalsContact O-O 3.08Å; H721-Q723 PolarHBondContact O-N 3.13Å
722A86.2Confident91.9Very high60 Ų6049.4 Ų49.450%0.49624%0.242SC..EExtended strand (participates in β ladder)trans-72.4119.4162.300000106.9L715 G716L715-A722 HydrophobicContact CD1-CB 4.11Å; G716-A722 CarbonylContact O-C 3.29Å; G716-A722 WeakPolarHBondContact O-CA 3.31Å
723Q91.9Very high91.7Very high86 Ų8656.9 Ų56.940%0.40227%0.271SS..EExtended strand (participates in β ladder)trans-122.2130.7-175.4-177.7172.4-13.100109.4G716 L718 H721G716-Q723 PolarHBondContact N-O 3.38Å; G716-Q723 PolarHBondContact O-N 3.03Å; L718-Q723 HydrophobicContact CB-CB 4.36Å; L718-Q723 HydrophobicContact CD1-CB 4.18Å; L718-Q723 HydrophobicContact CD1-CG 4.26Å; L718-Q723 VanDerWaalsContact CD1-OE1 3.3Å; H721-Q723 PolarHBondContact O-N 3.13Å
724L94.8Very high91.6Very high52 Ų5256.9 Ų56.927%0.27227%0.271SS..EExtended strand (participates in β ladder)trans-92.9121.2170.1-68.4159.6000107.9V689 L713 L714 L715V689-L724 HydrophobicContact CB-CD1 4.37Å; V689-L724 HydrophobicContact CG1-CD1 3.87Å; V689-L724 HydrophobicContact CG2-CD1 3.65Å; L713-L724 HydrophobicContact CB-CD2 4.2Å; L713-L724 HydrophobicContact CD1-CB 4.12Å; L713-L724 HydrophobicContact CD1-CD1 4.33Å; L713-L724 HydrophobicContact CD1-CD2 4.16Å; L713-L724 HydrophobicContact CD1-CG 4.44Å; L713-L724 HydrophobicContact CD2-CB 4.33Å; L714-L724 WeakPolarHBondContact O-CA 3.49Å; L715-L724 HydrophobicContact CB-CD2 3.86Å; L715-L724 HydrophobicContact CD1-CD2 3.79Å; L715-L724 HydrophobicContact CD1-CG 3.96Å; L715-L724 HydrophobicContact CG-CD2 4.38Å
725T96.3Very high91.6Very high3 Ų358.8 Ų58.82%0.01828%0.281CS..EExtended strand (participates in β ladder)trans-122.3133178.7-52.60000109.6L713 L714 V727 E729 L730L713-T725 CarbonylContact C-O 3.5Å; L713-T725 WeakPolarHBondContact CA-O 3.45Å; L714-T725 PolarHBondContact N-O 3.45Å; L714-T725 PolarHBondContact O-N 3.14Å; T725-V727 PolarHBondContact O-N 3.41Å; T725-E729 HydrophobicContact CG2-CB 4.34Å; T725-E729 HydrophobicContact CG2-CG 4.48Å; T725-L730 HydrophobicContact CG2-CD1 4.29Å; T725-L730 HydrophobicContact CG2-CD2 3.75Å; T725-L730 HydrophobicContact CG2-CG 3.74Å
726P97.4Very high91.5Very high17 Ų1762 Ų6211%0.1130%0.296CS..EExtended strand (participates in β ladder)trans-54.3132.9172.3-2635.3000111.9N710 A712 L713 L728 E729 L730N710-P726 HydrophobicContact CB-CG 4.38Å; N710-P726 WeakPolarHBondContact OD1-CG 3.38Å; A712-P726 WeakPolarHBondContact O-CA 3.46Å; L713-P726 HydrophobicContact CD2-CG 4.13Å; P726-L728 PolarHBondContact O-N 3.09Å; P726-E729 HydrophobicContact CB-CB 4.22Å; P726-E729 WeakPolarHBondContact O-CB 3.16Å; P726-E729 PolarHBondContact O-N 2.85Å; P726-E729 VanDerWaalsContact O-N 3.09Å; P726-L730 PolarHBondContact O-N 3.37Å
727V97.3Very high91.7Very high0 Ų065.9 Ų65.90%033%0.327CS..Hα-helixtrans-63.9-29.7-176.9-64.30000112.6Y505 C508 I509 V527 A712 L714 T725 L730 K731Y505-V727 HydrophobicContact CD2-CB 4.38Å; Y505-V727 HydrophobicContact CD2-CG1 4.28Å; Y505-V727 HydrophobicContact CE2-CB 4.11Å; Y505-V727 HydrophobicContact CE2-CG1 4.42Å; C508-V727 HydrophobicContact CB-CG1 4.17Å; I509-V727 HydrophobicContact CG1-CB 3.91Å; I509-V727 HydrophobicContact CG1-CG2 3.97Å; V527-V727 HydrophobicContact CG2-CG1 4.43Å; A712-V727 HydrophobicContact CB-CG2 3.92Å; A712-V727 PolarHBondContact O-N 3.38Å; L714-V727 HydrophobicContact CB-CG1 4.17Å; T725-V727 PolarHBondContact O-N 3.41Å; V727-L730 PolarHBondContact O-N 3.33Å; V727-K731 PolarHBondContact O-N 3.11Å; V727-K731 VanDerWaalsContact O-N 3.13Å
728L96.6Very high92.1Very high46 Ų4667.6 Ų67.624%0.24133%0.333CS..Hα-helixtrans-73.1-29.9176-62.1-171.4000112.8I509 T512 E513 P709 P726 L730 K731I509-L728 HydrophobicContact CG1-CD2 4.42Å; I509-L728 HydrophobicContact CG2-CD2 3.99Å; T512-L728 HydrophobicContact CG2-CD1 3.87Å; T512-L728 HydrophobicContact CG2-CG 4.1Å; E513-L728 HydrophobicContact CG-CD2 3.84Å; P709-L728 HydrophobicContact CB-CD1 4.17Å; P726-L728 PolarHBondContact O-N 3.09Å; L728-L730 VanDerWaalsContact C-N 3.34Å; L728-K731 VanDerWaalsContact O-CB 3.28Å; L728-K731 WeakPolarHBondContact O-CB 3.37Å; L728-K731 PolarHBondContact O-N 2.91Å
729E95.9Very high92.7Very high87 Ų8769.8 Ų69.841%0.40734%0.339SS..Hα-helixtrans-66.4-40.7172.1-174.1-170.1150.300110.4T725 P726 K731T725-E729 HydrophobicContact CG2-CB 4.34Å; T725-E729 HydrophobicContact CG2-CG 4.48Å; P726-E729 HydrophobicContact CB-CB 4.22Å; P726-E729 WeakPolarHBondContact O-CB 3.16Å; P726-E729 PolarHBondContact O-N 2.85Å; P726-E729 VanDerWaalsContact O-N 3.09Å; E729-K731 VanDerWaalsContact C-N 3.25Å; E729-K731 PolarHBondContact O-N 3.28Å
730L95.8Very high93.6Very high13 Ų1364.4 Ų64.47%0.06832%0.315CS..Hα-helixtrans-66.9-27.6176.9-65.8175.3000112.5Y505 P537 L714 T725 P726 V727 L728 E732 R733 T734Y505-L730 HydrophobicContact CE2-CB 3.87Å; Y505-L730 HydrophobicContact CE2-CD1 4.23Å; Y505-L730 VanDerWaalsContact OH-CB 3.31Å; Y505-L730 WeakPolarHBondContact OH-CB 3.23Å; Y505-L730 PolarHBondContact OH-O 3.24Å; P537-L730 HydrophobicContact CB-CB 4.29Å; L714-L730 HydrophobicContact CB-CD1 3.79Å; L714-L730 HydrophobicContact CD1-CD1 4.1Å; L714-L730 HydrophobicContact CD2-CD1 4.05Å; L714-L730 HydrophobicContact CG-CD1 4.2Å; T725-L730 HydrophobicContact CG2-CD1 4.29Å; T725-L730 HydrophobicContact CG2-CD2 3.75Å; T725-L730 HydrophobicContact CG2-CG 3.74Å; P726-L730 PolarHBondContact O-N 3.37Å; V727-L730 PolarHBondContact O-N 3.33Å; L728-L730 VanDerWaalsContact C-N 3.34Å; L730-E732 PolarHBondContact O-N 3.5Å; L730-R733 CarbonylContact O-C 3.51Å; L730-R733 WeakPolarHBondContact O-CA 3.45Å; L730-R733 PolarHBondContact O-N 3.12Å; L730-T734 PolarHBondContact O-N 2.94Å; L730-T734 PolarHBondContact O-OG1 2.59Å
731K95.8Very high94.4Very high73 Ų7360.2 Ų60.232%0.31730%0.301SS..Hα-helixtrans-55.7-40.1-180-173.9175.8178.6170.90111.6Y505 I509 E513 V727 L728 E729 R733 T734 F736Y505-K731 WeakPolarHBondContact OH-CA 3.24Å; Y505-K731 PolarHBondContact OH-N 2.95Å; I509-K731 HydrophobicContact CD1-CB 4.08Å; I509-K731 HydrophobicContact CD1-CG 4.29Å; I509-K731 HydrophobicContact CG2-CD 4.03Å; E513-K731 IonicContact OE1-NZ 3.15Å; E513-K731 PolarHBondContact OE1-NZ 2.96Å; E513-K731 IonicContact OE2-NZ 3.05Å; E513-K731 PolarHBondContact OE2-NZ 3.48Å; V727-K731 PolarHBondContact O-N 3.11Å; V727-K731 VanDerWaalsContact O-N 3.13Å; L728-K731 VanDerWaalsContact O-CB 3.28Å; L728-K731 WeakPolarHBondContact O-CB 3.37Å; L728-K731 PolarHBondContact O-N 2.91Å; E729-K731 VanDerWaalsContact C-N 3.25Å; E729-K731 PolarHBondContact O-N 3.28Å; K731-R733 PolarHBondContact O-N 3.18Å; K731-T734 PolarHBondContact O-N 2.87Å; K731-F736 HydrophobicContact CG-CE2 3.7Å; K731-F736 HydrophobicContact CG-CZ 3.82Å
732E91.9Very high94.9Very high170 Ų17059.9 Ų59.979%0.79430%0.301SS*.THydrogen-bonded Turntrans-66.7-22.1178.5-60.2-175170.200113.3L730L730-E732 PolarHBondContact O-N 3.5Å
733R92.8Very high95Very high158 Ų15863.4 Ų63.460%0.59631%0.312SS*.THydrogen-bonded Turntrans-109.526.3-178.5-55.9-175.6-173.9175.96.4112.5L730 K731 M742L730-R733 CarbonylContact O-C 3.51Å; L730-R733 WeakPolarHBondContact O-CA 3.45Å; L730-R733 PolarHBondContact O-N 3.12Å; K731-R733 PolarHBondContact O-N 3.18Å; R733-M742 VanDerWaalsContact C-CG 3.48Å; R733-M742 VanDerWaalsContact O-CG 3.3Å; R733-M742 WeakPolarHBondContact O-CG 2.99Å; R733-M742 PolarHBondContact O-N 2.91Å; R733-M742 VanDerWaalsContact O-N 3.09Å
734T96.9Very high95.1Very high10 Ų1060.2 Ų60.26%0.06130%0.297CS..EExtended strand (participates in β ladder)trans-119.7129.6-176.6-58.80000110.8F502 Y505 P537 L730 K731 F736F502-T734 HydrophobicContact CE2-CG2 3.6Å; F502-T734 HydrophobicContact CZ-CG2 3.43Å; F502-T734 VanDerWaalsContact CZ-CG2 3.43Å; Y505-T734 HydrophobicContact CE1-CG2 4.01Å; Y505-T734 PolarHBondContact OH-OG1 3.21Å; P537-T734 HydrophobicContact CG-CG2 3.85Å; P537-T734 VanDerWaalsContact CG-OG1 3.27Å; P537-T734 WeakPolarHBondContact CG-OG1 3.47Å; L730-T734 PolarHBondContact O-N 2.94Å; L730-T734 PolarHBondContact O-OG1 2.59Å; K731-T734 PolarHBondContact O-N 2.87Å; T734-F736 HydrophobicContact CG2-CD1 4.31Å; T734-F736 HydrophobicContact CG2-CD2 3.71Å; T734-F736 HydrophobicContact CG2-CE1 4.19Å; T734-F736 HydrophobicContact CG2-CE2 3.59Å; T734-F736 HydrophobicContact CG2-CG 4.08Å; T734-F736 HydrophobicContact CG2-CZ 3.83Å; T734-F736 PolarHBondContact O-N 2.66Å
735D96.6Very high94.9Very high39 Ų3959.2 Ų59.221%0.20929%0.29CS..EExtended strand (participates in β ladder)trans-85.8101.6161.8-178.1-17.4000108.8A737 H738 R739 L740 M742D735-A737 WeakPolarHBondContact OD1-CB 3.27Å; D735-A737 PolarHBondContact OD1-N 2.96Å; D735-H738 PolarHBondContact OD1-N 2.72Å; D735-H738 IonicContact OD1-ND1 3.25Å; D735-H738 PolarHBondContact OD1-ND1 3.45Å; D735-H738 IonicContact OD2-CE1 3.38Å; D735-H738 IonicContact OD2-CG 3.63Å; D735-H738 IonicContact OD2-ND1 3.79Å; D735-H738 PolarHBondContact OD2-ND1 3.16Å; D735-R739 CarbonylContact O-C 3.44Å; D735-R739 WeakPolarHBondContact O-CA 3.34Å; D735-R739 PolarHBondContact O-N 3.35Å; D735-L740 HydrophobicContact CB-CB 4.32Å; D735-L740 PolarHBondContact N-O 3.44Å; D735-L740 PolarHBondContact O-N 3.07Å; D735-M742 HydrophobicContact CB-CE 3.95Å; D735-M742 HydrophobicContact CB-SD 4.43Å
736F95.9Very high94.8Very high70 Ų7059.2 Ų59.231%0.30729%0.289SS..THydrogen-bonded Turntrans-74-25.6178.8-77.1-89.6000113.5F502 Y505 H506 I509 K731 T734F502-F736 AromaticContact CE1-CD1 3.83Å; F502-F736 HydrophobicContact CE1-CD1 3.83Å; F502-F736 HydrophobicContact CE1-CE1 4.14Å; F502-F736 AromaticContact CZ-CD1 3.84Å; F502-F736 HydrophobicContact CZ-CD1 3.84Å; F502-F736 HydrophobicContact CZ-CE1 4.11Å; F502-F736 HydrophobicContact CZ-CG 4.37Å; Y505-F736 HydrophobicContact CE1-CE1 4.48Å; Y505-F736 HydrophobicContact CE1-CZ 4.3Å; H506-F736 AromaticContact CD2-CE1 3.95Å; I509-F736 HydrophobicContact CD1-CE1 4.35Å; I509-F736 HydrophobicContact CD1-CZ 3.86Å; K731-F736 HydrophobicContact CG-CE2 3.7Å; K731-F736 HydrophobicContact CG-CZ 3.82Å; T734-F736 HydrophobicContact CG2-CD1 4.31Å; T734-F736 HydrophobicContact CG2-CD2 3.71Å; T734-F736 HydrophobicContact CG2-CE1 4.19Å; T734-F736 HydrophobicContact CG2-CE2 3.59Å; T734-F736 HydrophobicContact CG2-CG 4.08Å; T734-F736 HydrophobicContact CG2-CZ 3.83Å; T734-F736 PolarHBondContact O-N 2.66Å
737A95.6Very high94.6Very high81 Ų8161.4 Ų61.467%0.66930%0.3SS*.THydrogen-bonded Turntrans-70-45-178.600000110.5D735D735-A737 WeakPolarHBondContact OD1-CB 3.27Å; D735-A737 PolarHBondContact OD1-N 2.96Å
738H96Very high94.3Very high62 Ų6265.5 Ų65.529%0.28732%0.317SS..THydrogen-bonded Turntrans-97.1-8.3178.6-54.1103.1000113.3Y579 F599 D735 L740Y579-H738 HydrophobicContact CD2-CB 3.98Å; Y579-H738 WeakPolarHBondContact CD2-O 3.43Å; Y579-H738 AromaticContact CE1-CD2 3.96Å; Y579-H738 HydrophobicContact CG-CB 3.98Å; F599-H738 HydrophobicContact CE1-CB 4.32Å; F599-H738 AromaticContact CZ-CD2 3.59Å; F599-H738 AromaticContact CZ-CG 3.87Å; F599-H738 AromaticContact CZ-NE2 3.73Å; D735-H738 PolarHBondContact OD1-N 2.72Å; D735-H738 IonicContact OD1-ND1 3.25Å; D735-H738 PolarHBondContact OD1-ND1 3.45Å; D735-H738 IonicContact OD2-CE1 3.38Å; D735-H738 IonicContact OD2-CG 3.63Å; D735-H738 IonicContact OD2-ND1 3.79Å; D735-H738 PolarHBondContact OD2-ND1 3.16Å; H738-L740 HydrophobicContact CB-CD1 3.93Å; H738-L740 HydrophobicContact CB-CG 4.12Å
739R96.9Very high94.1Very high79 Ų7963.3 Ų63.330%0.29831%0.306SS..THydrogen-bonded Turntrans60.653.2-178.5-56.5168.649167.6-3112.1F502 E503 N535 D735F502-R739 HydrophobicContact CB-CB 4.49Å; F502-R739 HydrophobicContact CD1-CB 3.96Å; F502-R739 HydrophobicContact CD1-CG 3.84Å; F502-R739 HydrophobicContact CD2-CB 3.8Å; F502-R739 HydrophobicContact CE1-CB 4.06Å; F502-R739 HydrophobicContact CE1-CG 3.84Å; F502-R739 HydrophobicContact CE2-CB 3.89Å; F502-R739 HydrophobicContact CG-CB 3.83Å; F502-R739 HydrophobicContact CG-CG 4.21Å; F502-R739 HydrophobicContact CZ-CB 4.02Å; F502-R739 HydrophobicContact CZ-CG 4.21Å; E503-R739 IonicContact OE1-CZ 3.07Å; E503-R739 IonicContact OE1-NH1 2.85Å; E503-R739 PolarHBondContact OE1-NH1 3.02Å; E503-R739 IonicContact OE1-NH2 3.75Å; E503-R739 PolarHBondContact OE1-NH2 3.49Å; E503-R739 IonicContact OE2-CZ 2.77Å; E503-R739 IonicContact OE2-NH2 2.58Å; E503-R739 PolarHBondContact OE2-NH2 3.21Å; N535-R739 PolarHBondContact ND2-O 3.37Å; D735-R739 CarbonylContact O-C 3.44Å; D735-R739 WeakPolarHBondContact O-CA 3.34Å; D735-R739 PolarHBondContact O-N 3.35Å
740L96.1Very high93.9Very high8 Ų859.5 Ų59.54%0.04229%0.288CS..EExtended strand (participates in β ladder)trans-125.7148.9-176.3-66.7174.5000111.8N535 C580 F599 D735 H738N535-L740 HydrophobicContact CB-CD2 4.4Å; C580-L740 HydrophobicContact CB-CD2 3.56Å; F599-L740 HydrophobicContact CD1-CD1 3.84Å; F599-L740 HydrophobicContact CE1-CD1 3.92Å; D735-L740 HydrophobicContact CB-CB 4.32Å; D735-L740 PolarHBondContact N-O 3.44Å; D735-L740 PolarHBondContact O-N 3.07Å; H738-L740 HydrophobicContact CB-CD1 3.93Å; H738-L740 HydrophobicContact CB-CG 4.12Å
741P94.7Very high93.7Very high17 Ų1760.6 Ų60.611%0.1130%0.296CS..EExtended strand (participates in β ladder)trans-71.2143.6159.730.9-31.7000110.5P537 D743 Q744P537-P741 HydrophobicContact CB-CB 4.35Å; P537-P741 HydrophobicContact CG-CB 4.31Å; P741-D743 VanDerWaalsContact C-N 3.32Å; P741-Q744 HydrophobicContact CG-CG 3.74Å
742M91Very high93.5Very high126 Ų12657.1 Ų57.162%0.62128%0.281SS*.SBendtrans-68-32.2176.4-68.6-68.5-175.400112.7R733 D735R733-M742 VanDerWaalsContact C-CG 3.48Å; R733-M742 VanDerWaalsContact O-CG 3.3Å; R733-M742 WeakPolarHBondContact O-CG 2.99Å; R733-M742 PolarHBondContact O-N 2.91Å; R733-M742 VanDerWaalsContact O-N 3.09Å; D735-M742 HydrophobicContact CB-CE 3.95Å; D735-M742 HydrophobicContact CB-SD 4.43Å
743D89.5Confident93.6Very high134 Ų13449.1 Ų49.172%0.71724%0.244SC*.  trans-106.3127.8174.6-176.425.2000110.9P741P741-D743 VanDerWaalsContact C-N 3.32Å
744Q92.7Very high93.5Very high20 Ų2044.5 Ų44.59%0.09323%0.226CC..  trans-132.891.9-172.7-71.3-175.1100.100110.1E600 P741 W746 L747E600-Q744 VanDerWaalsContact CG-NE2 3.33Å; E600-Q744 PolarHBondContact OE1-OE1 3.13Å; P741-Q744 HydrophobicContact CG-CG 3.74Å; Q744-W746 HydrophobicContact CB-CZ2 4.39Å; Q744-W746 PolarHBondContact O-N 3.26Å; Q744-L747 HydrophobicContact CB-CD1 3.75Å; Q744-L747 HydrophobicContact CB-CG 3.9Å; Q744-L747 WeakPolarHBondContact O-CB 3.27Å; Q744-L747 PolarHBondContact O-N 2.92Å; Q744-L747 VanDerWaalsContact O-N 3.08Å
745W91.4Very high93.2Very high31 Ų3144.9 Ų44.912%0.11723%0.228CC..G310 helixtrans-54.1-27.3-173.173.4-91.3000114.6N540 Y541 Y582 K748 L749N540-W745 VanDerWaalsContact CB-CD1 3.5Å; N540-W745 HydrophobicContact CB-CG 4.3Å; N540-W745 VanDerWaalsContact CG-CD1 3.4Å; N540-W745 PolarHBondContact O-NE1 3.48Å; Y541-W745 HydrophobicContact CD1-CZ2 4.18Å; Y541-W745 AromaticContact CE1-CH2 3.86Å; Y541-W745 HydrophobicContact CE1-CH2 3.86Å; Y541-W745 AromaticContact CE1-CZ2 3.31Å; Y541-W745 HydrophobicContact CE1-CZ2 3.31Å; Y541-W745 HydrophobicContact CE2-CZ2 4.47Å; Y541-W745 AromaticContact CZ-CH2 3.88Å; Y541-W745 AromaticContact CZ-CZ2 3.48Å; Y541-W745 VanDerWaalsContact CZ-CZ2 3.48Å; Y541-W745 VanDerWaalsContact OH-CH2 3.25Å; Y541-W745 WeakPolarHBondContact OH-CH2 2.93Å; Y541-W745 WeakPolarHBondContact OH-CZ2 3.48Å; Y582-W745 AromaticContact CE2-CZ2 3.98Å; Y582-W745 HydrophobicContact CE2-CZ2 3.98Å; W745-K748 VanDerWaalsContact O-CD 3.22Å; W745-K748 WeakPolarHBondContact O-CD 3.16Å; W745-K748 WeakPolarHBondContact O-CE 3.25Å; W745-K748 WeakPolarHBondContact O-CG 3.26Å; W745-L749 HydrophobicContact CH2-CD1 4.12Å; W745-L749 HydrophobicContact CZ3-CD1 3.69Å; W745-L749 HydrophobicContact CZ3-CG 4.47Å
746W93.2Very high93Very high3 Ų343 Ų431%0.01122%0.218CC..G310 helixtrans-82.2-14.2-173.556-95.1000112.8Y582 T585 I598 E600 Q744 K748 L749Y582-W746 HydrophobicContact CD2-CB 4.18Å; Y582-W746 AromaticContact CD2-CD1 3.5Å; Y582-W746 VanDerWaalsContact CD2-CD1 3.5Å; Y582-W746 HydrophobicContact CD2-CD2 4.18Å; Y582-W746 AromaticContact CD2-CG 3.68Å; Y582-W746 HydrophobicContact CD2-CG 3.68Å; Y582-W746 AromaticContact CD2-NE1 3.83Å; Y582-W746 HydrophobicContact CE2-CG 4.45Å; Y582-W746 VanDerWaalsContact N-CH2 3.3Å; Y582-W746 VanDerWaalsContact N-CZ2 3.32Å; T585-W746 HydrophobicContact CG2-CE3 4.22Å; T585-W746 HydrophobicContact CG2-CZ3 4.43Å; T585-W746 WeakPolarHBondContact OG1-CZ3 3.38Å; I598-W746 HydrophobicContact CD1-CH2 4.26Å; I598-W746 HydrophobicContact CD1-CZ3 3.95Å; E600-W746 VanDerWaalsContact CD-CH2 3.45Å; E600-W746 HydrophobicContact CG-CH2 4.19Å; E600-W746 VanDerWaalsContact OE1-CH2 3.22Å; E600-W746 WeakPolarHBondContact OE1-CH2 3.42Å; E600-W746 VanDerWaalsContact OE1-CZ2 3.26Å; E600-W746 WeakPolarHBondContact OE1-CZ2 3.43Å; Q744-W746 HydrophobicContact CB-CZ2 4.39Å; Q744-W746 PolarHBondContact O-N 3.26Å; W746-K748 PolarHBondContact O-N 2.93Å; W746-L749 VanDerWaalsContact O-CB 3.29Å; W746-L749 WeakPolarHBondContact O-CB 3.45Å; W746-L749 PolarHBondContact O-N 3.26Å
747L94.1Very high92.6Very high62 Ų6239.8 Ų39.833%0.32520%0.204SC..G310 helixtrans-58.9-32.6176.7-72.2173.7000112.2I598 E600 Q744 L749 H750 P751I598-L747 HydrophobicContact CD1-CD2 3.88Å; E600-L747 HydrophobicContact CB-CD1 4.28Å; E600-L747 HydrophobicContact CB-CD2 3.57Å; E600-L747 HydrophobicContact CG-CD1 4.46Å; E600-L747 HydrophobicContact CG-CD2 3.97Å; Q744-L747 HydrophobicContact CB-CD1 3.75Å; Q744-L747 HydrophobicContact CB-CG 3.9Å; Q744-L747 WeakPolarHBondContact O-CB 3.27Å; Q744-L747 PolarHBondContact O-N 2.92Å; Q744-L747 VanDerWaalsContact O-N 3.08Å; L747-L749 PolarHBondContact O-N 3.26Å; L747-L749 VanDerWaalsContact O-N 3.1Å; L747-H750 WeakPolarHBondContact O-CB 3.33Å; L747-H750 PolarHBondContact O-N 2.79Å; L747-P751 WeakPolarHBondContact O-CD 3.34Å
748K91Very high91.8Very high86 Ų8638.7 Ų38.737%0.37420%0.195SC..G310 helixtrans-63.9-1417577-162.1175.7-172.60114.3W745 W746 S766W745-K748 VanDerWaalsContact O-CD 3.22Å; W745-K748 WeakPolarHBondContact O-CD 3.16Å; W745-K748 WeakPolarHBondContact O-CE 3.25Å; W745-K748 WeakPolarHBondContact O-CG 3.26Å; W746-K748 PolarHBondContact O-N 2.93Å; K748-S766 VanDerWaalsContact NZ-CB 3.34Å
749L93.2Very high90.1Very high1 Ų137.3 Ų37.31%0.00519%0.187CC..G310 helixtrans-87.8-14.6176.2-58.8-179.5000112.8R310 L586 L589 W745 W746 L747 L752 L753 Y763R310-L749 HydrophobicContact CG-CD2 4.15Å; L586-L749 HydrophobicContact CD2-CD1 3.54Å; L589-L749 HydrophobicContact CD2-CB 4.28Å; W745-L749 HydrophobicContact CH2-CD1 4.12Å; W745-L749 HydrophobicContact CZ3-CD1 3.69Å; W745-L749 HydrophobicContact CZ3-CG 4.47Å; W746-L749 VanDerWaalsContact O-CB 3.29Å; W746-L749 WeakPolarHBondContact O-CB 3.45Å; W746-L749 PolarHBondContact O-N 3.26Å; L747-L749 PolarHBondContact O-N 3.26Å; L747-L749 VanDerWaalsContact O-N 3.1Å; L749-L752 WeakPolarHBondContact O-CB 3.33Å; L749-L752 PolarHBondContact O-N 3.33Å; L749-L752 VanDerWaalsContact O-N 3.15Å; L749-L753 PolarHBondContact O-N 2.68Å; L749-Y763 HydrophobicContact CD2-CE2 4.42Å
750H90.3Very high88.2Confident7 Ų744.2 Ų44.23%0.03222%0.219CC..Hα-helixtrans-63.1-44176.5-167.9-71.6000112.3T585 A596 Q601 L747 L752 L753 R754T585-H750 HydrophobicContact CG2-CB 4.05Å; A596-H750 PolarHBondContact O-NE2 3.37Å; Q601-H750 PolarHBondContact OE1-CE1 3.1Å; Q601-H750 PolarHBondContact OE1-ND1 3.34Å; Q601-H750 PolarHBondContact OE1-NE2 3.1Å; L747-H750 WeakPolarHBondContact O-CB 3.33Å; L747-H750 PolarHBondContact O-N 2.79Å; H750-L752 VanDerWaalsContact C-N 3.26Å; H750-L752 PolarHBondContact O-N 3.49Å; H750-L753 WeakPolarHBondContact O-CB 3.48Å; H750-L753 PolarHBondContact O-N 3.24Å; H750-L753 VanDerWaalsContact O-N 3.12Å; H750-R754 PolarHBondContact O-N 3.41Å; H750-R754 VanDerWaalsContact O-N 3.1Å
751P91.4Very high86.3Confident36 Ų3645.5 Ų45.523%0.23423%0.229CC..Hα-helixtrans-56-36.9169.6-28.736.5000114.1L747 R754 L755 S761 T762L747-P751 WeakPolarHBondContact O-CD 3.34Å; P751-R754 PolarHBondContact O-N 3.39Å; P751-L755 VanDerWaalsContact O-CB 3.3Å; P751-L755 WeakPolarHBondContact O-CB 3.45Å; P751-L755 PolarHBondContact O-N 3.29Å; P751-S761 WeakPolarHBondContact CA-OG 3.5Å; P751-S761 WeakPolarHBondContact CB-OG 3.18Å; P751-S761 PolarHBondContact O-OG 3.46Å; P751-T762 WeakPolarHBondContact CB-O 3.34Å
752L93Very high84.2Confident0 Ų051.1 Ų51.10%026%0.263CS..Hα-helixtrans-66.5-41.2177.2-178.859.8000111.6R310 A313 L589 L749 H750 R754 L755 L756 Y763R310-L752 HydrophobicContact CG-CD2 4.2Å; A313-L752 HydrophobicContact CB-CD1 3.66Å; A313-L752 HydrophobicContact CB-CD2 4.36Å; L589-L752 HydrophobicContact CD1-CD2 4.46Å; L589-L752 HydrophobicContact CD1-CG 4.26Å; L589-L752 HydrophobicContact CD2-CD2 4.23Å; L749-L752 WeakPolarHBondContact O-CB 3.33Å; L749-L752 PolarHBondContact O-N 3.33Å; L749-L752 VanDerWaalsContact O-N 3.15Å; H750-L752 VanDerWaalsContact C-N 3.26Å; H750-L752 PolarHBondContact O-N 3.49Å; L752-R754 VanDerWaalsContact C-N 3.32Å; L752-R754 PolarHBondContact O-N 3.49Å; L752-L755 PolarHBondContact O-N 2.97Å; L752-L756 HydrophobicContact CD1-CD1 3.92Å; L752-L756 HydrophobicContact CD1-CG 3.92Å; L752-L756 HydrophobicContact CG-CD1 3.91Å; L752-L756 HydrophobicContact CG-CG 4.31Å; L752-L756 WeakPolarHBondContact O-CB 3.3Å; L752-L756 VanDerWaalsContact O-CG 3.27Å; L752-L756 WeakPolarHBondContact O-CG 3.21Å; L752-L756 PolarHBondContact O-N 3.45Å; L752-Y763 HydrophobicContact CB-CD2 3.63Å; L752-Y763 HydrophobicContact CB-CE2 3.73Å; L752-Y763 HydrophobicContact CB-CG 4.1Å; L752-Y763 HydrophobicContact CD1-CD1 4.01Å; L752-Y763 HydrophobicContact CD1-CD2 4.49Å; L752-Y763 HydrophobicContact CD1-CE1 4.17Å; L752-Y763 HydrophobicContact CD1-CG 4.17Å; L752-Y763 HydrophobicContact CD2-CE1 4.35Å; L752-Y763 HydrophobicContact CD2-CE2 4.21Å; L752-Y763 HydrophobicContact CG-CD2 4.5Å; L752-Y763 HydrophobicContact CG-CE2 4.4Å
753L93.8Very high82.8Confident2 Ų246.2 Ų46.21%0.0124%0.238CC..Hα-helixtrans-56.1-48.9173.6177.1155.4000110.6T585 L589 A596 L749 H750 L756 A757T585-L753 WeakPolarHBondContact O-CD1 3.32Å; L589-L753 HydrophobicContact CB-CB 4.41Å; L589-L753 HydrophobicContact CB-CD1 4.31Å; L589-L753 HydrophobicContact CD1-CB 4.35Å; A596-L753 HydrophobicContact CB-CD1 3.97Å; L749-L753 PolarHBondContact O-N 2.68Å; H750-L753 WeakPolarHBondContact O-CB 3.48Å; H750-L753 PolarHBondContact O-N 3.24Å; H750-L753 VanDerWaalsContact O-N 3.12Å; L753-L756 PolarHBondContact O-N 2.6Å; L753-A757 WeakPolarHBondContact O-CB 3.01Å; L753-A757 PolarHBondContact O-N 3.43Å; L753-A757 VanDerWaalsContact O-N 3.14Å
754R90.6Very high81.3Confident61 Ų6143.5 Ų43.523%0.2323%0.234CC..Hα-helixtrans-64.7-45.7179.5-68.5-168.375.3140.75.4112.2H750 P751 L752 L756 A757 A758 Y759H750-R754 PolarHBondContact O-N 3.41Å; H750-R754 VanDerWaalsContact O-N 3.1Å; P751-R754 PolarHBondContact O-N 3.39Å; L752-R754 VanDerWaalsContact C-N 3.32Å; L752-R754 PolarHBondContact O-N 3.49Å; R754-L756 PolarHBondContact O-N 2.87Å; R754-A757 CarbonylContact O-C 3.53Å; R754-A757 WeakPolarHBondContact O-CA 3.48Å; R754-A757 PolarHBondContact O-N 3.2Å; R754-A758 PolarHBondContact O-N 3.25Å; R754-Y759 WeakPolarHBondContact O-CB 3.24Å; R754-Y759 PolarHBondContact O-N 3.04Å
755L91.2Very high79.4Confident17 Ų1744.4 Ų44.49%0.08924%0.241CC..Hα-helixtrans-56.5-51.8176.4179.164.7000110.3V35 W65 P751 L752 A757 A758V35-L755 HydrophobicContact CG1-CD2 4.43Å; V35-L755 HydrophobicContact CG2-CD2 4.05Å; W65-L755 VanDerWaalsContact CH2-O 3.27Å; W65-L755 WeakPolarHBondContact CH2-O 3.38Å; P751-L755 VanDerWaalsContact O-CB 3.3Å; P751-L755 WeakPolarHBondContact O-CB 3.45Å; P751-L755 PolarHBondContact O-N 3.29Å; L752-L755 PolarHBondContact O-N 2.97Å; L755-A757 PolarHBondContact O-N 3.34Å; L755-A758 PolarHBondContact O-N 3.24Å
756L91.7Very high77.3Confident1 Ų144.6 Ų44.61%0.00525%0.247CC..THydrogen-bonded Turntrans-66.4-7.3177.5-67.4175.7000113.5R30 A31 R34 V35 W65 L589 L752 L753 R754R30-L756 PolarHBondContact NH2-O 2.84Å; R30-L756 VanDerWaalsContact NH2-O 3.15Å; A31-L756 HydrophobicContact CB-CD2 4.26Å; R34-L756 HydrophobicContact CB-CD2 3.79Å; R34-L756 VanDerWaalsContact CD-O 3.29Å; R34-L756 WeakPolarHBondContact CD-O 3.5Å; R34-L756 PolarHBondContact NH1-O 2.93Å; V35-L756 HydrophobicContact CG2-CD2 3.8Å; W65-L756 VanDerWaalsContact CZ2-O 3.28Å; W65-L756 WeakPolarHBondContact CZ2-O 3.4Å; L589-L756 HydrophobicContact CD1-CD1 3.7Å; L752-L756 HydrophobicContact CD1-CD1 3.92Å; L752-L756 HydrophobicContact CD1-CG 3.92Å; L752-L756 HydrophobicContact CG-CD1 3.91Å; L752-L756 HydrophobicContact CG-CG 4.31Å; L752-L756 WeakPolarHBondContact O-CB 3.3Å; L752-L756 VanDerWaalsContact O-CG 3.27Å; L752-L756 WeakPolarHBondContact O-CG 3.21Å; L752-L756 PolarHBondContact O-N 3.45Å; L753-L756 PolarHBondContact O-N 2.6Å; R754-L756 PolarHBondContact O-N 2.87Å
757A86.6Confident74.6Confident2 Ų250.6 Ų50.62%0.01730%0.297CS..THydrogen-bonded Turntrans-106.113.1173.900000113.4D594 K618 L753 R754 L755 Y759D594-A757 HydrophobicContact CB-CB 4.46Å; D594-A757 WeakPolarHBondContact O-CB 3.3Å; K618-A757 WeakPolarHBondContact CE-O 3.36Å; K618-A757 PolarHBondContact NZ-O 3.18Å; L753-A757 WeakPolarHBondContact O-CB 3.01Å; L753-A757 PolarHBondContact O-N 3.43Å; L753-A757 VanDerWaalsContact O-N 3.14Å; R754-A757 CarbonylContact O-C 3.53Å; R754-A757 WeakPolarHBondContact O-CA 3.48Å; R754-A757 PolarHBondContact O-N 3.2Å; L755-A757 PolarHBondContact O-N 3.34Å; A757-Y759 VanDerWaalsContact C-N 3.33Å; A757-Y759 HydrophobicContact CB-CD2 4.05Å; A757-Y759 HydrophobicContact CB-CE2 4.4Å
758A79.5Confident73.7Confident57 Ų5750 Ų5047%0.47130%0.296SS..THydrogen-bonded Turntrans68.922.818000000114.8W65 R754 L755W65-A758 HydrophobicContact CD2-CB 4.33Å; W65-A758 HydrophobicContact CH2-CB 3.95Å; W65-A758 HydrophobicContact CZ2-CB 3.52Å; W65-A758 HydrophobicContact CZ3-CB 4.49Å; R754-A758 PolarHBondContact O-N 3.25Å; L755-A758 PolarHBondContact O-N 3.24Å
759Y60.3Low72.8Confident33 Ų3348.1 Ų48.113%0.12929%0.292CS..  trans-85.5140.3165.2-72.6-84.6000109.8D594 D611 A614 Y626 R754 A757 S761D594-Y759 WeakPolarHBondContact O-CE2 3.36Å; D611-Y759 PolarHBondContact OD1-OH 3.06Å; A614-Y759 HydrophobicContact CB-CE1 3.95Å; A614-Y759 VanDerWaalsContact CB-OH 3.27Å; A614-Y759 WeakPolarHBondContact CB-OH 3.26Å; Y626-Y759 PolarHBondContact OH-OH 3.46Å; R754-Y759 WeakPolarHBondContact O-CB 3.24Å; R754-Y759 PolarHBondContact O-N 3.04Å; A757-Y759 VanDerWaalsContact C-N 3.33Å; A757-Y759 HydrophobicContact CB-CD2 4.05Å; A757-Y759 HydrophobicContact CB-CE2 4.4Å; Y759-S761 PolarHBondContact O-N 3.1Å
760K56.6Low71.6Confident224 Ų22450.7 Ų50.797%0.97431%0.308SS*.  trans-63.6109.1168.5-75.5-171.1177.1-174.70108.5
761S55.6Low70.5Confident35 Ų3553.3 Ų53.325%0.24532%0.324CS..  trans-150.8138.1178.8-171.80000109.6P751 Y759P751-S761 WeakPolarHBondContact CA-OG 3.5Å; P751-S761 WeakPolarHBondContact CB-OG 3.18Å; P751-S761 PolarHBondContact O-OG 3.46Å; Y759-S761 PolarHBondContact O-N 3.1Å
762T52.3Low69.2Low135 Ų13554.4 Ų54.483%0.82833%0.329SS*.  trans-88121.8177.4-30.20000109.1P751P751-T762 WeakPolarHBondContact CB-O 3.34Å
763Y60.4Low67.6Low24 Ų2458 Ų589%0.09435%0.351CS..  trans-107.2128.2174.2175.2-114.4000109.7A313 L317 L749 L752 T765A313-Y763 HydrophobicContact CB-CD1 4.44Å; A313-Y763 HydrophobicContact CB-CE1 4.04Å; L317-Y763 HydrophobicContact CD1-CD1 3.92Å; L317-Y763 HydrophobicContact CD1-CE1 4.13Å; L749-Y763 HydrophobicContact CD2-CE2 4.42Å; L752-Y763 HydrophobicContact CB-CD2 3.63Å; L752-Y763 HydrophobicContact CB-CE2 3.73Å; L752-Y763 HydrophobicContact CB-CG 4.1Å; L752-Y763 HydrophobicContact CD1-CD1 4.01Å; L752-Y763 HydrophobicContact CD1-CD2 4.49Å; L752-Y763 HydrophobicContact CD1-CE1 4.17Å; L752-Y763 HydrophobicContact CD1-CG 4.17Å; L752-Y763 HydrophobicContact CD2-CE1 4.35Å; L752-Y763 HydrophobicContact CD2-CE2 4.21Å; L752-Y763 HydrophobicContact CG-CD2 4.5Å; L752-Y763 HydrophobicContact CG-CE2 4.4Å; Y763-T765 HydrophobicContact CE1-CG2 3.99Å
764A58.6Low65.8Low76 Ų7662 Ų6263%0.62838%0.376SS*.  trans-113.3137.217400000109.7
765T51.9Low63.9Low39 Ų3962.1 Ų62.124%0.23939%0.387CS..  trans-75.4157.4-179.441.10000112.4D314 L317 Y763 A767D314-T765 HydrophobicContact CB-CG2 4.11Å; D314-T765 WeakPolarHBondContact OD1-CG2 3.46Å; L317-T765 HydrophobicContact CB-CG2 4.49Å; L317-T765 HydrophobicContact CD1-CG2 3.3Å; Y763-T765 HydrophobicContact CE1-CG2 3.99Å; T765-A767 PolarHBondContact O-N 3.21Å
766S48Very low61.6Low36 Ų3665.8 Ų65.825%0.25241%0.412SS..  trans-82.817.7-176.857.20000115K748K748-S766 VanDerWaalsContact NZ-CB 3.34Å
767A37.5Very low58.9Low128 Ų12871.7 Ų71.7100%1.05845%0.449SS*.  trans-103.10-173.400000111T765T765-A767 PolarHBondContact O-N 3.21Å

Retrieved 767 of 767 residues in 810.3 ms (Link to these results)