A0A077Z476_TRITR Loading...

histone deacetylase

AlphaFold DB , UniProt , Accession A0A077Z476, Species TRITR (Trichuris trichiura, Whipworm), Gene n/a, Length 329 aa.

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Site Residue pLDDT pLDDT confidence pLDDT10 pLDDT10 confidence SASA SASA [Ų] SASA10 SASA10 [Ų] RSA RSA unformatted RSA10 RSA10 unformatted Surface Surface10 (not used) Disorder (not used) Disorder Sec. str. Secondary structure Isomer Phi (φ) Psi (ψ) Omega (ω) Chi 1 (χ1) Chi 2 (χ2) Chi 3 (χ3) Chi 4 (χ4) Chi 5 (χ5) Tau (τ) Contacts (colored by PAE) Contact details
1M74.6Confident92.1Very high103 Ų10384 Ų8451%0.50749%0.485SS..  0-53.40-64.4-52.1-78.500112.9E38 L39 R42M1-E38 HydrophobicContact CE-CG 4.26Å; M1-E38 WeakPolarHBondContact CE-OE1 3.36Å; M1-E38 HydrophobicContact SD-CG 4.45Å; M1-L39 HydrophobicContact SD-CD2 4.13Å; M1-R42 HydrophobicContact CE-CB 3.92Å; M1-R42 HydrophobicContact SD-CB 4.43Å
2N84.9Confident92.4Very high137 Ų13784.8 Ų84.873%0.73351%0.509SS*.  trans-91-4.1-178.3-57.8-26.4000115D4N2-D4 WeakPolarHBondContact CB-OD2 3.39Å
3G83Confident92.8Very high65 Ų6578.7 Ų78.767%0.6747%0.474SS*.SBendtrans85.513.2-173.200000114.2C5G3-C5 PolarHBondContact O-N 3.5Å
4D90.3Very high93.2Very high138 Ų13873.3 Ų73.374%0.73844%0.442SS*.SBendtrans-69.4-21.5-179.5-55.6-34.7000113.4N2N2-D4 WeakPolarHBondContact CB-OD2 3.39Å
5C94Very high93.5Very high75 Ų7572.6 Ų72.651%0.50744%0.435SS..  trans-150.2146.4179.162.50000111G3G3-C5 PolarHBondContact O-N 3.5Å
6D95.1Very high93.8Very high132 Ų13268.3 Ų68.371%0.70641%0.409SS*.SBendtrans-84.4-28.8170.8-58.8-53.5000112P170 L171D6-P170 WeakPolarHBondContact O-CA 3.44Å; D6-L171 PolarHBondContact O-N 3.21Å
7I97.9Very high94.1Very high50 Ų5064.5 Ų64.526%0.25639%0.386SS..EExtended strand (participates in β ladder)trans-127.4126.8178.7-51179.5000109.2I9 R165 L171 L173 A195I7-I9 HydrophobicContact CG2-CG1 4.44Å; I7-R165 HydrophobicContact CD1-CG 4.25Å; I7-L171 CarbonylContact C-O 3.54Å; I7-L171 VanDerWaalsContact CA-O 3.28Å; I7-L171 WeakPolarHBondContact CA-O 3.47Å; I7-L171 HydrophobicContact CD1-CD2 4.5Å; I7-L171 HydrophobicContact CG1-CB 4.24Å; I7-L171 HydrophobicContact CG2-CB 4.32Å; I7-L171 HydrophobicContact CG2-CD2 4.31Å; I7-L171 HydrophobicContact CG2-CG 4.34Å; I7-L173 HydrophobicContact CG2-CD1 4.37Å; I7-L173 HydrophobicContact CG2-CG 4.41Å; I7-A195 HydrophobicContact CD1-CB 4.48Å; I7-A195 WeakPolarHBondContact CD1-O 3.24Å; I7-A195 HydrophobicContact CG2-CB 4.36Å
8A98Very high94.3Very high37 Ų3761 Ų6131%0.30637%0.365SS..EExtended strand (participates in β ladder)trans-114.4149.3170.700000110L171 L172 L173A8-L171 PolarHBondContact N-O 3.29Å; A8-L172 HydrophobicContact CB-CD1 3.92Å; A8-L172 CarbonylContact O-C 3.52Å; A8-L172 WeakPolarHBondContact O-CA 3.05Å; A8-L173 PolarHBondContact O-N 2.68Å
9I98.4Very high94.5Very high66 Ų6659.7 Ų59.734%0.33835%0.354SS..EExtended strand (participates in β ladder)trans-132.5131.4-175.6-63.3171.7000109.2I7 W11 L173 T192 A195I7-I9 HydrophobicContact CG2-CG1 4.44Å; I9-W11 HydrophobicContact CD1-CZ2 4.31Å; I9-W11 HydrophobicContact CG2-CD2 3.54Å; I9-W11 HydrophobicContact CG2-CE3 4.22Å; I9-W11 HydrophobicContact CG2-CG 3.86Å; I9-W11 HydrophobicContact CG2-CH2 4.22Å; I9-W11 HydrophobicContact CG2-CZ2 3.55Å; I9-W11 VanDerWaalsContact CG2-NE1 3.31Å; I9-L173 CarbonylContact C-O 3.58Å; I9-L173 WeakPolarHBondContact CA-O 2.95Å; I9-L173 HydrophobicContact CG1-CB 4.17Å; I9-L173 HydrophobicContact CG1-CD1 4.18Å; I9-T192 HydrophobicContact CD1-CG2 4.38Å; I9-A195 HydrophobicContact CD1-CB 4.23Å
10N98.1Very high94.4Very high73 Ų7366.6 Ų66.639%0.3938%0.379SS..EExtended strand (participates in β ladder)trans-137.584.8169.117930.7000110.8A12 G13 L173 L174 G175N10-A12 PolarHBondContact O-N 3.26Å; N10-G13 PolarHBondContact ND2-N 3.03Å; N10-G13 PolarHBondContact O-N 3.07Å; N10-G13 VanDerWaalsContact O-N 3.08Å; N10-L173 PolarHBondContact N-O 3.31Å; N10-L174 HydrophobicContact CB-CD2 3.92Å; N10-L174 WeakPolarHBondContact O-CA 3.09Å; N10-G175 PolarHBondContact O-N 3.09Å
11W98.3Very high94.5Very high48 Ų4869.4 Ų69.418%0.18240%0.402CS..THydrogen-bonded Turntrans-65.9-19.4-179.7-61.3136.4000114.5I9 G13 C137 L173 G175 W188 E191 T192I9-W11 HydrophobicContact CD1-CZ2 4.31Å; I9-W11 HydrophobicContact CG2-CD2 3.54Å; I9-W11 HydrophobicContact CG2-CE3 4.22Å; I9-W11 HydrophobicContact CG2-CG 3.86Å; I9-W11 HydrophobicContact CG2-CH2 4.22Å; I9-W11 HydrophobicContact CG2-CZ2 3.55Å; I9-W11 VanDerWaalsContact CG2-NE1 3.31Å; W11-G13 VanDerWaalsContact C-N 3.29Å; W11-C137 HydrophobicContact CZ3-CB 4.03Å; W11-L173 HydrophobicContact CH2-CB 3.96Å; W11-L173 HydrophobicContact CH2-CD1 4.03Å; W11-L173 HydrophobicContact CZ3-CB 4.09Å; W11-G175 WeakPolarHBondContact O-CA 3.31Å; W11-W188 HydrophobicContact CB-CD2 4.21Å; W11-W188 HydrophobicContact CB-CE3 3.7Å; W11-W188 HydrophobicContact CB-CZ3 3.99Å; W11-W188 HydrophobicContact CD2-CB 3.89Å; W11-W188 HydrophobicContact CD2-CD2 4.22Å; W11-W188 AromaticContact CD2-CG 3.95Å; W11-W188 HydrophobicContact CD2-CG 3.95Å; W11-W188 HydrophobicContact CE3-CB 4.24Å; W11-W188 AromaticContact CE3-CD1 3.92Å; W11-W188 HydrophobicContact CE3-CD2 4.12Å; W11-W188 AromaticContact CE3-CG 3.87Å; W11-W188 HydrophobicContact CE3-CG 3.87Å; W11-W188 HydrophobicContact CG-CB 4.21Å; W11-W188 HydrophobicContact CG-CD2 4.29Å; W11-W188 HydrophobicContact CG-CE3 4.13Å; W11-W188 HydrophobicContact CG-CG 4.36Å; W11-W188 HydrophobicContact CZ2-CB 4.35Å; W11-W188 HydrophobicContact CZ3-CG 4.32Å; W11-W188 VanDerWaalsContact O-CH2 3.28Å; W11-W188 WeakPolarHBondContact O-CH2 3.19Å; W11-W188 WeakPolarHBondContact O-CZ3 3.4Å; W11-E191 HydrophobicContact CH2-CB 3.94Å; W11-E191 HydrophobicContact CZ2-CB 4.29Å; W11-T192 WeakPolarHBondContact CZ2-OG1 3.3Å; W11-T192 PolarHBondContact NE1-OG1 2.87Å; W11-T192 VanDerWaalsContact NE1-OG1 3.08Å
12A96Very high95.4Very high93 Ų9370.6 Ų70.677%0.76941%0.406SS*.THydrogen-bonded Turntrans-83.7-5.7175.200000113.2N10N10-A12 PolarHBondContact O-N 3.26Å
13G97.5Very high96Very high6 Ų666.6 Ų66.66%0.06239%0.392CS..  trans-92.5-16717500000112.8N10 W11 D31 G175 G176N10-G13 PolarHBondContact ND2-N 3.03Å; N10-G13 PolarHBondContact O-N 3.07Å; N10-G13 VanDerWaalsContact O-N 3.08Å; W11-G13 VanDerWaalsContact C-N 3.29Å; G13-D31 WeakPolarHBondContact CA-OD2 3.32Å; G13-G175 CarbonylContact O-C 3.58Å; G13-G175 VanDerWaalsContact O-C 3.29Å; G13-G175 WeakPolarHBondContact O-CA 3.41Å; G13-G175 PolarHBondContact O-N 2.69Å; G13-G176 PolarHBondContact O-N 3.05Å
14G98.3Very high96.6Very high3 Ų364.8 Ų64.83%0.03137%0.369CS..  trans98.825.3178.500000114H16 D31G14-H16 PolarHBondContact O-N 3.17Å; G14-D31 PolarHBondContact N-OD1 2.6Å; G14-D31 VanDerWaalsContact N-OD1 3.11Å; G14-D31 PolarHBondContact N-OD2 3.11Å
15L98.2Very high96.8Very high63 Ų6359.1 Ų59.133%0.3334%0.343SS..  trans-78.963.2-177.4-62.9179.5000111.6H17 A18 C27 V29 D31L15-H17 VanDerWaalsContact C-N 3.3Å; L15-H17 PolarHBondContact O-N 3.27Å; L15-A18 PolarHBondContact O-N 2.79Å; L15-C27 WeakPolarHBondContact CA-SG 3.47Å; L15-C27 HydrophobicContact CB-CB 3.85Å; L15-C27 HydrophobicContact CD2-CB 4.45Å; L15-V29 WeakPolarHBondContact CB-O 3.33Å; L15-V29 WeakPolarHBondContact CD1-O 3.37Å; L15-D31 WeakPolarHBondContact CB-OD1 3.42Å; L15-D31 PolarHBondContact N-OD1 2.65Å
16H98.7Very high96.8Very high4 Ų460.6 Ų60.62%0.01934%0.341CS..THydrogen-bonded Turntrans-71.6-12.8-165.365.8175.1000116.4G14 N30 I32 D50 D52 H54 G56 G58 V59G14-H16 PolarHBondContact O-N 3.17Å; H16-N30 PolarHBondContact O-ND2 3.09Å; H16-I32 HydrophobicContact CB-CD1 3.41Å; H16-I32 VanDerWaalsContact CB-CD1 3.41Å; H16-D50 IonicContact CE1-OD2 3.89Å; H16-D50 IonicContact CG-OD2 3.97Å; H16-D50 IonicContact ND1-OD1 3.75Å; H16-D50 IonicContact ND1-OD2 3.87Å; H16-D50 PolarHBondContact ND1-OD2 3.44Å; H16-D52 VanDerWaalsContact CE1-CB 3.48Å; H16-D52 WeakPolarHBondContact CE1-CB 3.31Å; H16-D52 IonicContact CE1-OD1 3.55Å; H16-D52 IonicContact CE1-OD2 3.59Å; H16-D52 IonicContact NE2-OD1 3.01Å; H16-D52 IonicContact NE2-OD2 3.87Å; H16-H54 PolarHBondContact CE1-O 2.67Å; H16-G56 VanDerWaalsContact ND1-CA 3.35Å; H16-G56 WeakPolarHBondContact ND1-CA 3.15Å; H16-G58 WeakPolarHBondContact O-CA 3.25Å; H16-G58 PolarHBondContact O-N 2.96Å; H16-V59 HydrophobicContact CB-CG2 3.85Å; H16-V59 PolarHBondContact O-N 3.41Å
17H98.6Very high96.9Very high4 Ų454.7 Ų54.72%0.01931%0.31CS..THydrogen-bonded Turntrans-88.5-22.2-179.1-65.4-52.6000113.6L15 K19 S24 C27 H55 D57 F81L15-H17 VanDerWaalsContact C-N 3.3Å; L15-H17 PolarHBondContact O-N 3.27Å; H17-K19 WeakPolarHBondContact O-CD 3.45Å; H17-K19 WeakPolarHBondContact O-CE 3.46Å; H17-K19 PolarHBondContact O-N 2.88Å; H17-S24 WeakPolarHBondContact CB-O 3.39Å; H17-C27 HydrophobicContact CB-CB 4.02Å; H17-H55 PolarHBondContact CE1-O 2.87Å; H17-H55 PolarHBondContact ND1-O 2.98Å; H17-D57 WeakPolarHBondContact CA-OD1 3.47Å; H17-D57 IonicContact CE1-OD1 3.66Å; H17-D57 IonicContact CG-OD1 3.43Å; H17-D57 IonicContact ND1-OD1 3.73Å; H17-D57 PolarHBondContact ND1-OD1 2.85Å; H17-F81 AromaticContact CD2-CE1 3.67Å; H17-F81 AromaticContact CE1-CE1 3.62Å; H17-F81 AromaticContact CG-CE1 3.87Å; H17-F81 AromaticContact ND1-CE1 3.83Å; H17-F81 AromaticContact NE2-CE1 3.47Å; H17-F81 WeakPolarHBondContact NE2-CE1 3.41Å
18A98Very high96.8Very high1 Ų160.3 Ų60.31%0.00833%0.329CS..  trans-59.9132.6-178.600000110.4L15 C27 N30L15-A18 PolarHBondContact O-N 2.79Å; A18-C27 HydrophobicContact CB-CB 3.64Å; A18-C27 WeakPolarHBondContact CB-O 3.14Å; A18-C27 VanDerWaalsContact N-CB 3.28Å; A18-N30 HydrophobicContact CB-CB 3.84Å; A18-N30 WeakPolarHBondContact O-CB 3.47Å; A18-N30 PolarHBondContact O-ND2 2.63Å
19K97Very high96.8Very high36 Ų3662.5 Ų62.516%0.15734%0.339CS..  trans-102.9176.9-178.9-52-56.7-174.4143.10110.7H17 C21 E22 D57 G58 E61H17-K19 WeakPolarHBondContact O-CD 3.45Å; H17-K19 WeakPolarHBondContact O-CE 3.46Å; H17-K19 PolarHBondContact O-N 2.88Å; K19-C21 VanDerWaalsContact C-N 3.27Å; K19-C21 PolarHBondContact O-N 2.83Å; K19-E22 HydrophobicContact CB-CB 4.12Å; K19-E22 HydrophobicContact CG-CB 4.47Å; K19-E22 PolarHBondContact N-O 3.25Å; K19-D57 WeakPolarHBondContact CE-OD2 3.37Å; K19-D57 VanDerWaalsContact NZ-CG 3.29Å; K19-D57 PolarHBondContact NZ-O 3.13Å; K19-D57 IonicContact NZ-OD1 2.76Å; K19-D57 IonicContact NZ-OD2 2.79Å; K19-D57 PolarHBondContact NZ-OD2 3.32Å; K19-G58 VanDerWaalsContact CD-CA 3.48Å; K19-E61 WeakPolarHBondContact CD-OE2 3.34Å; K19-E61 WeakPolarHBondContact CE-OE2 3.36Å; K19-E61 IonicContact NZ-OE2 3.97Å; K19-E61 PolarHBondContact NZ-OE2 3Å
20K94.1Very high96.8Very high198 Ų19860.1 Ų60.186%0.86133%0.327SS*.SBendtrans-59.7-35.7180-173.2-179.5177.2-177.80113.3
21C94.6Very high96.8Very high125 Ų12558.1 Ų58.185%0.84532%0.316SS*.SBendtrans-135.919.2-174.3-59.60000112.9K19K19-C21 VanDerWaalsContact C-N 3.27Å; K19-C21 PolarHBondContact O-N 2.83Å
22E94.7Very high96.8Very high129 Ų12955.9 Ų55.960%0.60331%0.308SS*.  trans-152.8131.4-173.1174177.2-167.300110K19K19-E22 HydrophobicContact CB-CB 4.12Å; K19-E22 HydrophobicContact CG-CB 4.47Å; K19-E22 PolarHBondContact N-O 3.25Å
23A96.6Very high96.9Very high53 Ų5352.4 Ų52.444%0.43828%0.277SS..  trans-79.9141.316600000109C27 Y28A23-C27 VanDerWaalsContact CA-O 3.25Å; A23-C27 WeakPolarHBondContact CA-O 3.43Å; A23-C27 WeakPolarHBondContact CB-O 3.25Å; A23-Y28 HydrophobicContact CB-CD1 3.69Å; A23-Y28 HydrophobicContact CB-CE1 4.14Å; A23-Y28 HydrophobicContact CB-CG 4.31Å
24S96.7Very high96.9Very high27 Ų2757.1 Ų57.119%0.18930%0.3CS..BIsolated β-bridgetrans-154.5146.3-176.5-179.20000110H17 F26 C27H17-S24 WeakPolarHBondContact CB-O 3.39Å; S24-F26 PolarHBondContact O-N 3.1Å; S24-C27 PolarHBondContact N-O 3.45Å; S24-C27 WeakPolarHBondContact O-CA 3.26Å; S24-C27 WeakPolarHBondContact O-CB 3.47Å; S24-C27 PolarHBondContact O-N 3.4Å
25G94.3Very high96.9Very high19 Ų1958.2 Ų58.220%0.19631%0.309CS..THydrogen-bonded Turntrans51.549.2175.300000114.1C27G25-C27 PolarHBondContact O-N 3.38Å; G25-C27 PolarHBondContact O-SG 3.31Å
26F94.2Very high97Very high105 Ų10555.2 Ų55.246%0.46129%0.293SS..THydrogen-bonded Turntrans62.84.7-174.7-43.9-59.6000115.7S24 L147 Y179 E286S24-F26 PolarHBondContact O-N 3.1Å; F26-L147 HydrophobicContact CE2-CD1 4.35Å; F26-Y179 HydrophobicContact CD2-CE1 4.04Å; F26-Y179 WeakPolarHBondContact CD2-OH 3.35Å; F26-Y179 AromaticContact CE2-CE1 3.91Å; F26-Y179 HydrophobicContact CE2-CE1 3.91Å; F26-E286 VanDerWaalsContact CE1-CD 3.46Å; F26-E286 HydrophobicContact CE1-CG 3.6Å; F26-E286 WeakPolarHBondContact CE1-OE1 3.44Å; F26-E286 HydrophobicContact CZ-CG 3.91Å
27C97.3Very high96.9Very high8 Ų859.3 Ų59.35%0.05432%0.315CS..BIsolated β-bridgetrans-100.5121.1-178-58.50000111L15 H17 A18 A23 S24 G25L15-C27 WeakPolarHBondContact CA-SG 3.47Å; L15-C27 HydrophobicContact CB-CB 3.85Å; L15-C27 HydrophobicContact CD2-CB 4.45Å; H17-C27 HydrophobicContact CB-CB 4.02Å; A18-C27 HydrophobicContact CB-CB 3.64Å; A18-C27 WeakPolarHBondContact CB-O 3.14Å; A18-C27 VanDerWaalsContact N-CB 3.28Å; A23-C27 VanDerWaalsContact CA-O 3.25Å; A23-C27 WeakPolarHBondContact CA-O 3.43Å; A23-C27 WeakPolarHBondContact CB-O 3.25Å; S24-C27 PolarHBondContact N-O 3.45Å; S24-C27 WeakPolarHBondContact O-CA 3.26Å; S24-C27 WeakPolarHBondContact O-CB 3.47Å; S24-C27 PolarHBondContact O-N 3.4Å; G25-C27 PolarHBondContact O-N 3.38Å; G25-C27 PolarHBondContact O-SG 3.31Å
28Y95.9Very high96.8Very high168 Ų16862.3 Ų62.366%0.65933%0.329SS*.SBendtrans-102.3-29.7177.3-63.6-90000113.9A23A23-Y28 HydrophobicContact CB-CD1 3.69Å; A23-Y28 HydrophobicContact CB-CE1 4.14Å; A23-Y28 HydrophobicContact CB-CG 4.31Å
29V96.4Very high96.8Very high84 Ų8463.3 Ų63.351%0.50933%0.334SS..SBendtrans-133.4126.1179.41770000108.2L15 D31 L34L15-V29 WeakPolarHBondContact CB-O 3.33Å; L15-V29 WeakPolarHBondContact CD1-O 3.37Å; V29-D31 PolarHBondContact O-N 2.63Å; V29-D31 VanDerWaalsContact O-N 3.08Å; V29-L34 HydrophobicContact CG1-CD1 3.96Å
30N98.3Very high96.7Very high15 Ų1562.4 Ų62.48%0.0833%0.331CS..  trans-83.983.8177.4-160.8-46.4000110.3H16 A18 I32 V33 L34H16-N30 PolarHBondContact O-ND2 3.09Å; A18-N30 HydrophobicContact CB-CB 3.84Å; A18-N30 WeakPolarHBondContact O-CB 3.47Å; A18-N30 PolarHBondContact O-ND2 2.63Å; N30-I32 PolarHBondContact O-N 2.76Å; N30-I32 WeakPolarHBondContact OD1-CB 3.41Å; N30-I32 PolarHBondContact OD1-N 2.81Å; N30-V33 HydrophobicContact CB-CB 4.09Å; N30-V33 HydrophobicContact CB-CG2 4.13Å; N30-V33 VanDerWaalsContact CG-CG2 3.41Å; N30-V33 PolarHBondContact O-N 3.43Å; N30-V33 VanDerWaalsContact OD1-CG2 3.3Å; N30-V33 WeakPolarHBondContact OD1-CG2 3.43Å; N30-V33 PolarHBondContact OD1-N 3.17Å; N30-L34 WeakPolarHBondContact O-CG 3.25Å; N30-L34 PolarHBondContact O-N 3.29Å
31D98.2Very high96.8Very high32 Ų3254.8 Ų54.817%0.17130%0.301CS..Hα-helixtrans-60.4-31179.967.3-60.3000112.3G13 G14 L15 V29 L34 A35G13-D31 WeakPolarHBondContact CA-OD2 3.32Å; G14-D31 PolarHBondContact N-OD1 2.6Å; G14-D31 VanDerWaalsContact N-OD1 3.11Å; G14-D31 PolarHBondContact N-OD2 3.11Å; L15-D31 WeakPolarHBondContact CB-OD1 3.42Å; L15-D31 PolarHBondContact N-OD1 2.65Å; V29-D31 PolarHBondContact O-N 2.63Å; V29-D31 VanDerWaalsContact O-N 3.08Å; D31-L34 PolarHBondContact O-N 2.93Å; D31-A35 WeakPolarHBondContact O-CB 3.48Å; D31-A35 PolarHBondContact O-N 2.82Å
32I98.7Very high96.7Very high0 Ų055.3 Ų55.30%029%0.285CS..Hα-helixtrans-63.6-50.5176.8-51163.8000110.5H16 N30 L34 A35 I36 Y48 V59 V134 Q136 L174H16-I32 HydrophobicContact CB-CD1 3.41Å; H16-I32 VanDerWaalsContact CB-CD1 3.41Å; N30-I32 PolarHBondContact O-N 2.76Å; N30-I32 WeakPolarHBondContact OD1-CB 3.41Å; N30-I32 PolarHBondContact OD1-N 2.81Å; I32-L34 VanDerWaalsContact C-N 3.3Å; I32-L34 PolarHBondContact O-N 3.35Å; I32-A35 PolarHBondContact O-N 2.95Å; I32-I36 HydrophobicContact CG2-CD1 3.83Å; I32-I36 HydrophobicContact CG2-CG1 4.42Å; I32-I36 VanDerWaalsContact O-CG1 3.31Å; I32-I36 WeakPolarHBondContact O-CG1 3.28Å; I32-I36 PolarHBondContact O-N 3.19Å; I32-Y48 HydrophobicContact CD1-CE2 4.23Å; I32-Y48 HydrophobicContact CG2-CD2 3.8Å; I32-Y48 HydrophobicContact CG2-CE2 3.49Å; I32-Y48 VanDerWaalsContact CG2-CE2 3.49Å; I32-V59 HydrophobicContact CB-CG2 3.89Å; I32-V59 HydrophobicContact CD1-CG2 3.65Å; I32-V59 HydrophobicContact CG1-CG2 4.4Å; I32-V59 HydrophobicContact CG2-CG1 4.05Å; I32-V59 HydrophobicContact CG2-CG2 3.84Å; I32-V134 HydrophobicContact CG2-CG1 4.16Å; I32-Q136 HydrophobicContact CD1-CG 4.36Å; I32-L174 HydrophobicContact CB-CD1 4.24Å; I32-L174 HydrophobicContact CG1-CD1 3.61Å; I32-L174 HydrophobicContact CG2-CD1 4.17Å
33V98.6Very high96.7Very high21 Ų2150.6 Ų50.613%0.12726%0.263CS..Hα-helixtrans-60-43.7178.8167.90000110.4N30 I36 L37 V59 A62 F63N30-V33 HydrophobicContact CB-CB 4.09Å; N30-V33 HydrophobicContact CB-CG2 4.13Å; N30-V33 VanDerWaalsContact CG-CG2 3.41Å; N30-V33 PolarHBondContact O-N 3.43Å; N30-V33 VanDerWaalsContact OD1-CG2 3.3Å; N30-V33 WeakPolarHBondContact OD1-CG2 3.43Å; N30-V33 PolarHBondContact OD1-N 3.17Å; V33-I36 PolarHBondContact O-N 3.33Å; V33-L37 HydrophobicContact CG1-CD1 3.99Å; V33-L37 HydrophobicContact CG1-CG 4.4Å; V33-L37 WeakPolarHBondContact O-CB 3.32Å; V33-L37 VanDerWaalsContact O-CG 3.25Å; V33-L37 WeakPolarHBondContact O-CG 3.46Å; V33-L37 PolarHBondContact O-N 2.97Å; V33-V59 HydrophobicContact CG2-CG2 4.44Å; V33-A62 HydrophobicContact CB-CB 4.46Å; V33-A62 HydrophobicContact CG1-CB 3.98Å; V33-A62 HydrophobicContact CG2-CB 3.54Å; V33-F63 HydrophobicContact CB-CE2 4.39Å; V33-F63 HydrophobicContact CG1-CE2 4.39Å; V33-F63 HydrophobicContact CG1-CZ 4.12Å; V33-F63 HydrophobicContact CG2-CE2 3.96Å; V33-F63 HydrophobicContact CG2-CZ 4.49Å
34L98.2Very high96.6Very high104 Ų10449 Ų4955%0.54525%0.246SC..Hα-helixtrans-62.8-43.5177-62.9179000111.8V29 N30 D31 I32 L37 E38V29-L34 HydrophobicContact CG1-CD1 3.96Å; N30-L34 WeakPolarHBondContact O-CG 3.25Å; N30-L34 PolarHBondContact O-N 3.29Å; D31-L34 PolarHBondContact O-N 2.93Å; I32-L34 VanDerWaalsContact C-N 3.3Å; I32-L34 PolarHBondContact O-N 3.35Å; L34-L37 PolarHBondContact O-N 3.16Å; L34-E38 PolarHBondContact O-N 2.94Å
35A98.4Very high96.6Very high27 Ų2749.2 Ų49.222%0.22324%0.243CC..Hα-helixtrans-63.4-41.7176.200000112.2D31 I32 E38 L39 L172D31-A35 WeakPolarHBondContact O-CB 3.48Å; D31-A35 PolarHBondContact O-N 2.82Å; I32-A35 PolarHBondContact O-N 2.95Å; A35-E38 WeakPolarHBondContact O-CB 3.46Å; A35-E38 PolarHBondContact O-N 3.11Å; A35-L39 VanDerWaalsContact O-CG 3.28Å; A35-L39 WeakPolarHBondContact O-CG 3.45Å; A35-L39 PolarHBondContact O-N 3.47Å; A35-L172 HydrophobicContact CB-CD2 4Å
36I98.5Very high96.8Very high0 Ų048.3 Ų48.30%023%0.233CC..Hα-helixtrans-65.9-44.1177.3-68.7172.1000110.8I32 V33 E38 L39 L40 V46 Y48 V59 F63 V69 V134I32-I36 HydrophobicContact CG2-CD1 3.83Å; I32-I36 HydrophobicContact CG2-CG1 4.42Å; I32-I36 VanDerWaalsContact O-CG1 3.31Å; I32-I36 WeakPolarHBondContact O-CG1 3.28Å; I32-I36 PolarHBondContact O-N 3.19Å; V33-I36 PolarHBondContact O-N 3.33Å; I36-E38 VanDerWaalsContact C-N 3.25Å; I36-E38 PolarHBondContact O-N 2.65Å; I36-L39 PolarHBondContact O-N 2.88Å; I36-L39 VanDerWaalsContact O-N 3.15Å; I36-L40 HydrophobicContact CG2-CD1 4.05Å; I36-L40 HydrophobicContact CG2-CG 4.27Å; I36-L40 VanDerWaalsContact O-CG 3.26Å; I36-L40 WeakPolarHBondContact O-CG 3.28Å; I36-L40 PolarHBondContact O-N 2.91Å; I36-V46 HydrophobicContact CG1-CG1 4.1Å; I36-V46 HydrophobicContact CG2-CB 4.24Å; I36-V46 HydrophobicContact CG2-CG1 4.18Å; I36-V46 HydrophobicContact CG2-CG2 4.34Å; I36-Y48 HydrophobicContact CD1-CD2 4.3Å; I36-Y48 HydrophobicContact CD1-CG 4.42Å; I36-V59 HydrophobicContact CD1-CG1 4.07Å; I36-F63 HydrophobicContact CB-CE2 3.92Å; I36-F63 HydrophobicContact CB-CZ 3.71Å; I36-F63 HydrophobicContact CD1-CD2 4.42Å; I36-F63 HydrophobicContact CD1-CE2 3.76Å; I36-F63 HydrophobicContact CD1-CZ 4.44Å; I36-F63 HydrophobicContact CG1-CE2 4.44Å; I36-F63 HydrophobicContact CG2-CE1 3.93Å; I36-F63 HydrophobicContact CG2-CE2 3.72Å; I36-F63 HydrophobicContact CG2-CZ 3.36Å; I36-V69 HydrophobicContact CD1-CG1 4.41Å; I36-V69 HydrophobicContact CG2-CG1 4.17Å; I36-V69 HydrophobicContact CG2-CG2 3.54Å; I36-V134 HydrophobicContact CG1-CB 4.48Å; I36-V134 HydrophobicContact CG1-CG2 4Å
37L97.8Very high97.1Very high90 Ų9043.3 Ų43.347%0.47121%0.211SC..Hα-helixtrans-58-40.2175.6-72.3171.7000111.7V33 L34 L40 F63V33-L37 HydrophobicContact CG1-CD1 3.99Å; V33-L37 HydrophobicContact CG1-CG 4.4Å; V33-L37 WeakPolarHBondContact O-CB 3.32Å; V33-L37 VanDerWaalsContact O-CG 3.25Å; V33-L37 WeakPolarHBondContact O-CG 3.46Å; V33-L37 PolarHBondContact O-N 2.97Å; L34-L37 PolarHBondContact O-N 3.16Å; L37-L40 PolarHBondContact O-N 3.34Å; L37-F63 HydrophobicContact CD2-CE1 4.15Å; L37-F63 HydrophobicContact CG-CZ 4.39Å
38E96.8Very high97.1Very high67 Ų6743 Ų4331%0.31321%0.209SC..Hα-helixtrans-64.2-47173.8179.560.8-157.400112M1 L34 A35 I36 L40 T41 K260M1-E38 HydrophobicContact CE-CG 4.26Å; M1-E38 WeakPolarHBondContact CE-OE1 3.36Å; M1-E38 HydrophobicContact SD-CG 4.45Å; L34-E38 PolarHBondContact O-N 2.94Å; A35-E38 WeakPolarHBondContact O-CB 3.46Å; A35-E38 PolarHBondContact O-N 3.11Å; I36-E38 VanDerWaalsContact C-N 3.25Å; I36-E38 PolarHBondContact O-N 2.65Å; E38-L40 VanDerWaalsContact C-N 3.27Å; E38-L40 PolarHBondContact O-N 3.34Å; E38-T41 WeakPolarHBondContact O-CB 3.3Å; E38-T41 WeakPolarHBondContact O-CG2 3.32Å; E38-T41 PolarHBondContact O-N 3.33Å; E38-T41 VanDerWaalsContact O-N 3.11Å; E38-T41 PolarHBondContact O-OG1 2.88Å; E38-K260 WeakPolarHBondContact OE1-CE 3.14Å; E38-K260 IonicContact OE1-NZ 2.6Å; E38-K260 PolarHBondContact OE1-NZ 3.04Å; E38-K260 WeakPolarHBondContact OE2-CE 3.49Å; E38-K260 IonicContact OE2-NZ 2.63Å; E38-K260 PolarHBondContact OE2-NZ 3.2Å
39L96.8Very high97.3Very high21 Ų2135 Ų3511%0.1118%0.178CC..Hα-helixtrans-60.4-36.3177.4-73.2169.7000112.1M1 A35 I36 T41 R42 F43 V46 V132 V134M1-L39 HydrophobicContact SD-CD2 4.13Å; A35-L39 VanDerWaalsContact O-CG 3.28Å; A35-L39 WeakPolarHBondContact O-CG 3.45Å; A35-L39 PolarHBondContact O-N 3.47Å; I36-L39 PolarHBondContact O-N 2.88Å; I36-L39 VanDerWaalsContact O-N 3.15Å; L39-T41 PolarHBondContact O-N 3.15Å; L39-T41 VanDerWaalsContact O-N 3.11Å; L39-R42 PolarHBondContact O-N 3.22Å; L39-F43 HydrophobicContact CB-CD2 4.2Å; L39-F43 HydrophobicContact CD2-CD2 3.85Å; L39-F43 HydrophobicContact CD2-CE2 3.72Å; L39-F43 WeakPolarHBondContact O-CD2 3.32Å; L39-F43 PolarHBondContact O-N 3.05Å; L39-V46 HydrophobicContact CB-CG2 4.08Å; L39-V132 HydrophobicContact CD1-CG1 4.36Å; L39-V132 HydrophobicContact CD1-CG2 4.11Å; L39-V132 HydrophobicContact CD2-CG2 4.21Å; L39-V134 HydrophobicContact CD1-CG2 3.49Å; L39-V134 VanDerWaalsContact CD1-CG2 3.49Å
40L95.9Very high97.4Very high18 Ų1831 Ų319%0.09415%0.154CC..THydrogen-bonded Turntrans-65.4-10.3177.7-73171.9000114.2I36 L37 E38 R42 F43 V46 F63 R68 V69I36-L40 HydrophobicContact CG2-CD1 4.05Å; I36-L40 HydrophobicContact CG2-CG 4.27Å; I36-L40 VanDerWaalsContact O-CG 3.26Å; I36-L40 WeakPolarHBondContact O-CG 3.28Å; I36-L40 PolarHBondContact O-N 2.91Å; L37-L40 PolarHBondContact O-N 3.34Å; E38-L40 VanDerWaalsContact C-N 3.27Å; E38-L40 PolarHBondContact O-N 3.34Å; L40-R42 VanDerWaalsContact C-N 3.27Å; L40-F43 WeakPolarHBondContact CA-O 3.31Å; L40-V46 HydrophobicContact CD2-CG2 3.82Å; L40-V46 HydrophobicContact CG-CG2 4.1Å; L40-F63 HydrophobicContact CD1-CE1 4.32Å; L40-R68 HydrophobicContact CD2-CB 3.91Å; L40-R68 WeakPolarHBondContact CD2-O 3.42Å; L40-R68 PolarHBondContact O-NH2 3.28Å; L40-V69 HydrophobicContact CD1-CG2 3.75Å; L40-V69 HydrophobicContact CD2-CG2 4.2Å; L40-V69 HydrophobicContact CG-CG2 4.35Å
41T95Very high97.4Very high38 Ų3830.3 Ų30.323%0.23315%0.15CC..THydrogen-bonded Turntrans-79.2-12.4170.872.50000112.8E38 L39 I257 K260E38-T41 WeakPolarHBondContact O-CB 3.3Å; E38-T41 WeakPolarHBondContact O-CG2 3.32Å; E38-T41 PolarHBondContact O-N 3.33Å; E38-T41 VanDerWaalsContact O-N 3.11Å; E38-T41 PolarHBondContact O-OG1 2.88Å; L39-T41 PolarHBondContact O-N 3.15Å; L39-T41 VanDerWaalsContact O-N 3.11Å; T41-I257 WeakPolarHBondContact O-CG2 3.5Å; T41-K260 HydrophobicContact CG2-CD 4.47Å; T41-K260 HydrophobicContact CG2-CG 3.63Å
42R92.9Very high97.4Very high136 Ų13628.8 Ų28.851%0.51314%0.142SC..THydrogen-bonded Turntrans-125.8-32.7-178.3177.958.2-176.188-1.4113.6M1 L39 L40M1-R42 HydrophobicContact CE-CB 3.92Å; M1-R42 HydrophobicContact SD-CB 4.43Å; L39-R42 PolarHBondContact O-N 3.22Å; L40-R42 VanDerWaalsContact C-N 3.27Å
43F95Very high97.4Very high30 Ų3028.8 Ų28.813%0.13214%0.142CC..  trans-111142.9-178.9-59.2-73.8000110.1L39 L40 R68 E131 V132 P170L39-F43 HydrophobicContact CB-CD2 4.2Å; L39-F43 HydrophobicContact CD2-CD2 3.85Å; L39-F43 HydrophobicContact CD2-CE2 3.72Å; L39-F43 WeakPolarHBondContact O-CD2 3.32Å; L39-F43 PolarHBondContact O-N 3.05Å; L40-F43 WeakPolarHBondContact CA-O 3.31Å; F43-R68 PolarHBondContact O-NH2 3.42Å; F43-E131 HydrophobicContact CB-CB 4.3Å; F43-E131 HydrophobicContact CD1-CB 3.63Å; F43-E131 HydrophobicContact CE1-CB 4.41Å; F43-E131 HydrophobicContact CG-CB 4.35Å; F43-V132 HydrophobicContact CB-CG1 3.88Å; F43-V132 HydrophobicContact CD1-CB 4.41Å; F43-V132 HydrophobicContact CD1-CG1 4.34Å; F43-V132 HydrophobicContact CD2-CB 4.06Å; F43-V132 HydrophobicContact CD2-CG1 3.63Å; F43-V132 HydrophobicContact CE1-CB 4.49Å; F43-V132 HydrophobicContact CE2-CB 4.16Å; F43-V132 HydrophobicContact CE2-CG1 4.21Å; F43-V132 HydrophobicContact CE2-CG2 4.46Å; F43-V132 HydrophobicContact CG-CB 4.18Å; F43-V132 HydrophobicContact CG-CG1 3.69Å; F43-V132 HydrophobicContact CZ-CB 4.36Å; F43-P170 HydrophobicContact CE1-CG 4.5Å; F43-P170 HydrophobicContact CZ-CG 4.43Å
44Q95Very high97.4Very high18 Ų1828.2 Ų28.28%0.08414%0.138CC..SBendtrans-76.8-37.9179.3-168.748.842.100112.5R68 E131 V255Q44-R68 VanDerWaalsContact NE2-NE 3.16Å; Q44-R68 PolarHBondContact O-NE 3.35Å; Q44-E131 WeakPolarHBondContact CA-OE2 3.25Å; Q44-E131 WeakPolarHBondContact CB-OE2 3.1Å; Q44-E131 PolarHBondContact N-OE2 2.92Å; Q44-V255 VanDerWaalsContact NE2-CB 3.29Å; Q44-V255 PolarHBondContact NE2-O 2.85Å; Q44-V255 VanDerWaalsContact NE2-O 3.09Å; Q44-V255 PolarHBondContact OE1-O 3.33Å
45R97.2Very high97.5Very high32 Ų3223.4 Ų23.412%0.12111%0.112CC..  trans-138.2122.4-171.8-68.7-176-57.4-71.7-11.6111.1R68 Y128 Q129 E131 P253R45-R68 WeakPolarHBondContact CA-O 3.44Å; R45-Y128 HydrophobicContact CB-CE1 3.79Å; R45-Y128 HydrophobicContact CB-CE2 4.36Å; R45-Y128 VanDerWaalsContact CD-O 3.25Å; R45-Y128 WeakPolarHBondContact CD-O 3.48Å; R45-Y128 HydrophobicContact CG-CE1 4.43Å; R45-Y128 HydrophobicContact CG-CE2 4.1Å; R45-Y128 PolarHBondContact NE-O 3.04Å; R45-Q129 VanDerWaalsContact CZ-O 3.24Å; R45-Q129 PolarHBondContact NE-O 3.1Å; R45-Q129 PolarHBondContact NH2-O 3.18Å; R45-E131 PolarHBondContact O-N 2.97Å; R45-P253 PolarHBondContact NH1-O 2.94Å
46V98.4Very high97.5Very high0 Ų022.2 Ų22.20%010%0.103CC..EExtended strand (participates in β ladder)trans-111.8127177.6-177.70000108.9I36 L39 L40 R68 V69 M70 Y128 V132 V134I36-V46 HydrophobicContact CG1-CG1 4.1Å; I36-V46 HydrophobicContact CG2-CB 4.24Å; I36-V46 HydrophobicContact CG2-CG1 4.18Å; I36-V46 HydrophobicContact CG2-CG2 4.34Å; L39-V46 HydrophobicContact CB-CG2 4.08Å; L40-V46 HydrophobicContact CD2-CG2 3.82Å; L40-V46 HydrophobicContact CG-CG2 4.1Å; V46-R68 PolarHBondContact N-O 3.5Å; V46-R68 VanDerWaalsContact N-O 3.1Å; V46-V69 HydrophobicContact CB-CG2 4.47Å; V46-V69 WeakPolarHBondContact O-CA 3.42Å; V46-M70 PolarHBondContact O-N 3.44Å; V46-Y128 WeakPolarHBondContact O-CE1 3.49Å; V46-V132 HydrophobicContact CB-CG1 4.2Å; V46-V132 HydrophobicContact CG1-CG1 4.12Å; V46-V132 HydrophobicContact CG2-CG1 3.69Å; V46-V134 HydrophobicContact CG1-CG2 3.86Å
47L98.8Very high97.5Very high0 Ų022.8 Ų22.80%011%0.106CC..EExtended strand (participates in β ladder)trans-97118.9169.317364.4000108.8V49 M70 L72 I125 Y128 P130 V132 I133 V134L47-V49 HydrophobicContact CD1-CG2 4.34Å; L47-V49 HydrophobicContact CD2-CG2 3.96Å; L47-V49 HydrophobicContact CG-CG2 3.79Å; L47-M70 HydrophobicContact CD1-CB 3.95Å; L47-M70 HydrophobicContact CD1-CG 3.75Å; L47-M70 HydrophobicContact CD1-SD 3.87Å; L47-L72 HydrophobicContact CD1-CB 4.28Å; L47-I125 HydrophobicContact CD2-CD1 4.42Å; L47-I125 HydrophobicContact CD2-CG1 3.69Å; L47-Y128 HydrophobicContact CB-CD1 4.43Å; L47-P130 HydrophobicContact CB-CB 3.53Å; L47-P130 HydrophobicContact CB-CG 3.7Å; L47-P130 HydrophobicContact CD2-CG 4.02Å; L47-V132 PolarHBondContact N-O 2.86Å; L47-I133 HydrophobicContact CB-CG1 4.33Å; L47-I133 HydrophobicContact CD2-CD1 4.38Å; L47-I133 HydrophobicContact CD2-CG1 4.34Å; L47-I133 CarbonylContact O-C 3.4Å; L47-I133 VanDerWaalsContact O-CA 3.29Å; L47-I133 WeakPolarHBondContact O-CA 3.16Å; L47-V134 PolarHBondContact O-N 3.19Å
48Y98.9Very high97.5Very high2 Ų218.7 Ų18.71%0.0089%0.085CC..EExtended strand (participates in β ladder)trans-93.6123.8169.5175.2-111.9000109.3I32 I36 D50 V59 M70 T71 L72 V134 Q136I32-Y48 HydrophobicContact CD1-CE2 4.23Å; I32-Y48 HydrophobicContact CG2-CD2 3.8Å; I32-Y48 HydrophobicContact CG2-CE2 3.49Å; I32-Y48 VanDerWaalsContact CG2-CE2 3.49Å; I36-Y48 HydrophobicContact CD1-CD2 4.3Å; I36-Y48 HydrophobicContact CD1-CG 4.42Å; Y48-D50 HydrophobicContact CD1-CB 4.48Å; Y48-D50 HydrophobicContact CE1-CB 3.64Å; Y48-D50 VanDerWaalsContact OH-CG 3.28Å; Y48-D50 PolarHBondContact OH-OD2 3.36Å; Y48-V59 HydrophobicContact CD1-CB 4.24Å; Y48-V59 HydrophobicContact CD1-CG1 3.66Å; Y48-V59 HydrophobicContact CD2-CG1 4.26Å; Y48-V59 HydrophobicContact CE1-CB 3.88Å; Y48-V59 HydrophobicContact CE1-CG1 3.77Å; Y48-V59 HydrophobicContact CE1-CG2 4.18Å; Y48-V59 HydrophobicContact CE2-CG1 4.35Å; Y48-V59 HydrophobicContact CG-CG1 3.91Å; Y48-M70 PolarHBondContact N-O 3.22Å; Y48-T71 HydrophobicContact CD1-CG2 3.98Å; Y48-L72 PolarHBondContact O-N 3.3Å; Y48-V134 CarbonylContact C-O 3.54Å; Y48-V134 VanDerWaalsContact CA-O 3.29Å; Y48-V134 WeakPolarHBondContact CA-O 3.46Å; Y48-V134 HydrophobicContact CD2-CB 4.22Å; Y48-V134 HydrophobicContact CD2-CG1 4.05Å; Y48-V134 HydrophobicContact CE2-CG1 4.48Å; Y48-Q136 HydrophobicContact CE2-CB 3.84Å; Y48-Q136 VanDerWaalsContact OH-CB 3.29Å; Y48-Q136 WeakPolarHBondContact OH-CB 3.05Å
49V98.9Very high97.6Very high0 Ų015.5 Ų15.50%07%0.07CC..EExtended strand (participates in β ladder)trans-118.4129.4176.8-175.60000108.8L47 L72 F117 I133 V134 M135 Q136 I164L47-V49 HydrophobicContact CD1-CG2 4.34Å; L47-V49 HydrophobicContact CD2-CG2 3.96Å; L47-V49 HydrophobicContact CG-CG2 3.79Å; V49-L72 CarbonylContact C-O 3.58Å; V49-L72 WeakPolarHBondContact CA-O 3.29Å; V49-L72 HydrophobicContact CG2-CD2 4.46Å; V49-F117 HydrophobicContact CG1-CE2 3.91Å; V49-F117 HydrophobicContact CG1-CZ 4.04Å; V49-I133 HydrophobicContact CG2-CG2 4.1Å; V49-V134 PolarHBondContact N-O 3.41Å; V49-M135 HydrophobicContact CB-CG 4.41Å; V49-M135 CarbonylContact O-C 3.58Å; V49-M135 VanDerWaalsContact O-CA 3.26Å; V49-M135 WeakPolarHBondContact O-CA 3.35Å; V49-Q136 PolarHBondContact O-N 2.86Å; V49-I164 HydrophobicContact CG2-CD1 4.14Å
50D98.9Very high97.7Very high0 Ų015 Ų150%07%0.068CC..EExtended strand (participates in β ladder)trans-127.5121.5-174.2-165.2-28.3000110.3H16 Y48 D52 G56 L72 F74 Q136H16-D50 IonicContact CE1-OD2 3.89Å; H16-D50 IonicContact CG-OD2 3.97Å; H16-D50 IonicContact ND1-OD1 3.75Å; H16-D50 IonicContact ND1-OD2 3.87Å; H16-D50 PolarHBondContact ND1-OD2 3.44Å; Y48-D50 HydrophobicContact CD1-CB 4.48Å; Y48-D50 HydrophobicContact CE1-CB 3.64Å; Y48-D50 VanDerWaalsContact OH-CG 3.28Å; Y48-D50 PolarHBondContact OH-OD2 3.36Å; D50-D52 WeakPolarHBondContact OD1-CB 3.34Å; D50-D52 PolarHBondContact OD1-N 3.11Å; D50-G56 WeakPolarHBondContact OD2-CA 3.48Å; D50-L72 PolarHBondContact N-O 3.33Å; D50-F74 PolarHBondContact O-N 2.8Å; D50-Q136 HydrophobicContact CB-CB 4.36Å; D50-Q136 PolarHBondContact OD1-OE1 3.43Å
51V98.8Very high97.8Very high0 Ų019.3 Ų19.30%09%0.087CC..  trans-115.18.6178.9-59.10000113Y113 F117 M135 Q136 S141 H157 C160V51-Y113 WeakPolarHBondContact CB-OH 3.3Å; V51-Y113 WeakPolarHBondContact CG1-OH 3.4Å; V51-F117 HydrophobicContact CG1-CD2 4.3Å; V51-F117 HydrophobicContact CG1-CE2 3.58Å; V51-F117 HydrophobicContact CG1-CZ 4.3Å; V51-M135 HydrophobicContact CG1-CE 4.05Å; V51-M135 HydrophobicContact CG2-CE 4.07Å; V51-Q136 VanDerWaalsContact CG2-O 3.32Å; V51-Q136 WeakPolarHBondContact CG2-O 3.46Å; V51-Q136 PolarHBondContact N-O 3.03Å; V51-S141 VanDerWaalsContact O-CB 3.3Å; V51-S141 WeakPolarHBondContact O-CB 3.4Å; V51-S141 PolarHBondContact O-OG 3.37Å; V51-H157 VanDerWaalsContact CG2-CE1 3.41Å; V51-H157 WeakPolarHBondContact CG2-CE1 3.41Å; V51-H157 VanDerWaalsContact CG2-NE2 3.28Å; V51-H157 WeakPolarHBondContact CG2-NE2 3.33Å; V51-C160 HydrophobicContact CG1-CB 4.37Å
52D98.7Very high98Very high0 Ų020 Ų200%010%0.096CC..SBendtrans-55.9151.8166-156.9-82.9000110.7H16 D50 H54 Q136 G138 D140 G177H16-D52 VanDerWaalsContact CE1-CB 3.48Å; H16-D52 WeakPolarHBondContact CE1-CB 3.31Å; H16-D52 IonicContact CE1-OD1 3.55Å; H16-D52 IonicContact CE1-OD2 3.59Å; H16-D52 IonicContact NE2-OD1 3.01Å; H16-D52 IonicContact NE2-OD2 3.87Å; D50-D52 WeakPolarHBondContact OD1-CB 3.34Å; D50-D52 PolarHBondContact OD1-N 3.11Å; D52-H54 PolarHBondContact O-N 2.77Å; D52-H54 WeakPolarHBondContact OD1-CB 3.19Å; D52-H54 IonicContact OD1-CG 3.33Å; D52-H54 PolarHBondContact OD1-N 3.19Å; D52-H54 IonicContact OD1-ND1 2.75Å; D52-H54 PolarHBondContact OD1-ND1 3.47Å; D52-Q136 PolarHBondContact OD2-NE2 2.85Å; D52-G138 WeakPolarHBondContact OD2-CA 3.47Å; D52-D140 VanDerWaalsContact CG-OD1 3.26Å; D52-D140 VanDerWaalsContact OD1-OD1 3.1Å; D52-D140 VanDerWaalsContact OD1-OD2 3.1Å; D52-G177 PolarHBondContact OD2-N 3.34Å
53C98.5Very high98.2Very high0 Ų014.2 Ų14.20%08%0.075CC..SBendtrans-70.3-21.8175.983.70000112.7H75 K76 Y80 D140 L150C53-H75 CarbonylContact O-C 3.52Å; C53-H75 WeakPolarHBondContact O-CA 3.13Å; C53-H75 WeakPolarHBondContact O-CB 3.41Å; C53-K76 PolarHBondContact O-N 3.47Å; C53-Y80 PolarHBondContact SG-OH 3Å; C53-D140 PolarHBondContact N-OD1 3Å; C53-D140 PolarHBondContact SG-OD1 2.83Å; C53-D140 VanDerWaalsContact SG-OD1 3.39Å; C53-D140 PolarHBondContact SG-OD2 3.19Å; C53-L150 HydrophobicContact CB-CD1 3.98Å; C53-L150 HydrophobicContact CB-CG 4.11Å
54H98.7Very high98.4Very high10 Ų1015.9 Ų15.95%0.0468%0.081CC..SBendtrans-95.9149177.3-5193.4000111.3H16 D52 G56 H75 Y80 F81 D140H16-H54 PolarHBondContact CE1-O 2.67Å; D52-H54 PolarHBondContact O-N 2.77Å; D52-H54 WeakPolarHBondContact OD1-CB 3.19Å; D52-H54 IonicContact OD1-CG 3.33Å; D52-H54 PolarHBondContact OD1-N 3.19Å; D52-H54 IonicContact OD1-ND1 2.75Å; D52-H54 PolarHBondContact OD1-ND1 3.47Å; H54-G56 PolarHBondContact O-N 3.1Å; H54-H75 VanDerWaalsContact C-CB 3.49Å; H54-Y80 AromaticContact CD2-CE1 3.46Å; H54-Y80 VanDerWaalsContact CD2-CE1 3.46Å; H54-Y80 WeakPolarHBondContact CD2-CE1 3.43Å; H54-Y80 AromaticContact CD2-CZ 3.99Å; H54-Y80 AromaticContact NE2-CE1 3.7Å; H54-Y80 AromaticContact NE2-CZ 3.73Å; H54-Y80 PolarHBondContact NE2-OH 2.88Å; H54-F81 PolarHBondContact CD2-O 2.79Å; H54-D140 IonicContact CE1-OD2 3.61Å; H54-D140 PolarHBondContact CE1-OD2 2.95Å; H54-D140 IonicContact ND1-OD2 2.71Å; H54-D140 PolarHBondContact ND1-OD2 3.41Å
55H98.7Very high98.5Very high2 Ų219.5 Ų19.51%0.00910%0.104CC..  trans-66.1129175.9177.8-142.2000110.6H17 D57 E60 H75 P82 T84 G85 N101H17-H55 PolarHBondContact CE1-O 2.87Å; H17-H55 PolarHBondContact ND1-O 2.98Å; H55-D57 PolarHBondContact O-N 3Å; H55-E60 IonicContact CE1-OE1 3.75Å; H55-E60 PolarHBondContact CE1-OE1 2.99Å; H55-E60 IonicContact CE1-OE2 3.79Å; H55-E60 IonicContact NE2-OE1 2.61Å; H55-E60 IonicContact NE2-OE2 4Å; H55-E60 PolarHBondContact NE2-OE2 3.31Å; H55-H75 HydrophobicContact CB-CB 4.35Å; H55-H75 AromaticContact CD2-CE1 3.32Å; H55-H75 PolarHBondContact CD2-CE1 3.47Å; H55-H75 AromaticContact CD2-ND1 3.57Å; H55-H75 AromaticContact CG-CE1 3.64Å; H55-H75 AromaticContact CG-ND1 3.91Å; H55-H75 AromaticContact CG-NE2 3.96Å; H55-P82 HydrophobicContact CB-CG 4.02Å; H55-T84 VanDerWaalsContact ND1-C 3.32Å; H55-T84 PolarHBondContact ND1-OG1 3.28Å; H55-G85 VanDerWaalsContact CE1-CA 3.46Å; H55-G85 WeakPolarHBondContact CE1-CA 3.49Å; H55-G85 PolarHBondContact CE1-N 2.97Å; H55-G85 WeakPolarHBondContact ND1-CA 3.4Å; H55-G85 PolarHBondContact ND1-N 2.77Å; H55-N101 PolarHBondContact NE2-OD1 2.82Å
56G98.5Very high98.5Very high2 Ų219.7 Ų19.72%0.02111%0.109CC..  trans-69.655.8171.900000114H16 D50 H54 G58 V59 E60H16-G56 VanDerWaalsContact ND1-CA 3.35Å; H16-G56 WeakPolarHBondContact ND1-CA 3.15Å; D50-G56 WeakPolarHBondContact OD2-CA 3.48Å; H54-G56 PolarHBondContact O-N 3.1Å; G56-G58 PolarHBondContact O-N 2.92Å; G56-V59 PolarHBondContact O-N 2.92Å; G56-E60 PolarHBondContact O-N 3.45Å
57D98.5Very high98.4Very high13 Ų1320.5 Ų20.57%0.0711%0.114CC..Hα-helixtrans-67.1-31.8-167.472.7-44.2000113.5H17 K19 H55 E61 P82 T84H17-D57 WeakPolarHBondContact CA-OD1 3.47Å; H17-D57 IonicContact CE1-OD1 3.66Å; H17-D57 IonicContact CG-OD1 3.43Å; H17-D57 IonicContact ND1-OD1 3.73Å; H17-D57 PolarHBondContact ND1-OD1 2.85Å; K19-D57 WeakPolarHBondContact CE-OD2 3.37Å; K19-D57 VanDerWaalsContact NZ-CG 3.29Å; K19-D57 PolarHBondContact NZ-O 3.13Å; K19-D57 IonicContact NZ-OD1 2.76Å; K19-D57 IonicContact NZ-OD2 2.79Å; K19-D57 PolarHBondContact NZ-OD2 3.32Å; H55-D57 PolarHBondContact O-N 3Å; D57-E61 WeakPolarHBondContact O-CB 3.44Å; D57-E61 PolarHBondContact O-N 3.03Å; D57-P82 HydrophobicContact CB-CG 3.93Å; D57-T84 VanDerWaalsContact CB-OG1 3.31Å; D57-T84 WeakPolarHBondContact CB-OG1 3.17Å
58G98.6Very high98.3Very high3 Ų321.9 Ų21.93%0.03112%0.119CC..Hα-helixtrans-69.8-37.6174.800000112.8H16 K19 G56 A62H16-G58 WeakPolarHBondContact O-CA 3.25Å; H16-G58 PolarHBondContact O-N 2.96Å; K19-G58 VanDerWaalsContact CD-CA 3.48Å; G56-G58 PolarHBondContact O-N 2.92Å; G58-A62 WeakPolarHBondContact O-CB 3.46Å; G58-A62 PolarHBondContact O-N 3.11Å; G58-A62 VanDerWaalsContact O-N 3.16Å
59V98.8Very high98.3Very high0 Ų021.9 Ų21.90%012%0.119CC..Hα-helixtrans-70.1-46.5175.3-172.70000110.4H16 I32 V33 I36 Y48 G56 E61 A62 F63 T71H16-V59 HydrophobicContact CB-CG2 3.85Å; H16-V59 PolarHBondContact O-N 3.41Å; I32-V59 HydrophobicContact CB-CG2 3.89Å; I32-V59 HydrophobicContact CD1-CG2 3.65Å; I32-V59 HydrophobicContact CG1-CG2 4.4Å; I32-V59 HydrophobicContact CG2-CG1 4.05Å; I32-V59 HydrophobicContact CG2-CG2 3.84Å; V33-V59 HydrophobicContact CG2-CG2 4.44Å; I36-V59 HydrophobicContact CD1-CG1 4.07Å; Y48-V59 HydrophobicContact CD1-CB 4.24Å; Y48-V59 HydrophobicContact CD1-CG1 3.66Å; Y48-V59 HydrophobicContact CD2-CG1 4.26Å; Y48-V59 HydrophobicContact CE1-CB 3.88Å; Y48-V59 HydrophobicContact CE1-CG1 3.77Å; Y48-V59 HydrophobicContact CE1-CG2 4.18Å; Y48-V59 HydrophobicContact CE2-CG1 4.35Å; Y48-V59 HydrophobicContact CG-CG1 3.91Å; G56-V59 PolarHBondContact O-N 2.92Å; V59-E61 PolarHBondContact O-N 3.36Å; V59-A62 PolarHBondContact O-N 2.91Å; V59-F63 HydrophobicContact CG1-CD2 4.07Å; V59-F63 HydrophobicContact CG1-CE2 4.19Å; V59-F63 VanDerWaalsContact O-CD2 3.25Å; V59-F63 WeakPolarHBondContact O-CD2 3.37Å; V59-F63 PolarHBondContact O-N 3.27Å; V59-T71 HydrophobicContact CG1-CG2 4.32Å
60E98.8Very high98.3Very high12 Ų1221.9 Ų21.96%0.05612%0.119CC..Hα-helixtrans-58.1-48.8175.6173.2166.8115.400111.7H55 G56 A62 F63 Y64 T71 A99 N101H55-E60 IonicContact CE1-OE1 3.75Å; H55-E60 PolarHBondContact CE1-OE1 2.99Å; H55-E60 IonicContact CE1-OE2 3.79Å; H55-E60 IonicContact NE2-OE1 2.61Å; H55-E60 IonicContact NE2-OE2 4Å; H55-E60 PolarHBondContact NE2-OE2 3.31Å; G56-E60 PolarHBondContact O-N 3.45Å; E60-A62 VanDerWaalsContact C-N 3.33Å; E60-A62 PolarHBondContact O-N 3.08Å; E60-F63 CarbonylContact O-C 3.29Å; E60-F63 PolarHBondContact O-N 2.92Å; E60-F63 VanDerWaalsContact O-N 3.14Å; E60-Y64 HydrophobicContact CG-CD2 3.69Å; E60-Y64 HydrophobicContact CG-CE2 4.13Å; E60-Y64 WeakPolarHBondContact O-CA 3Å; E60-Y64 WeakPolarHBondContact O-CB 3.31Å; E60-Y64 PolarHBondContact O-N 3.14Å; E60-T71 HydrophobicContact CB-CG2 4.5Å; E60-A99 HydrophobicContact CG-CB 4.27Å; E60-A99 WeakPolarHBondContact OE2-CB 3.47Å; E60-N101 PolarHBondContact OE1-ND2 2.84Å; E60-N101 PolarHBondContact OE2-ND2 3.29Å; E60-N101 PolarHBondContact OE2-OD1 3.42Å
61E98.4Very high98.3Very high107 Ų10722.2 Ų22.250%0.512%0.121SC..Hα-helixtrans-58.2-44.9179.7-176.7-173.8130.700112.1K19 D57 V59 F63 Y64K19-E61 WeakPolarHBondContact CD-OE2 3.34Å; K19-E61 WeakPolarHBondContact CE-OE2 3.36Å; K19-E61 IonicContact NZ-OE2 3.97Å; K19-E61 PolarHBondContact NZ-OE2 3Å; D57-E61 WeakPolarHBondContact O-CB 3.44Å; D57-E61 PolarHBondContact O-N 3.03Å; V59-E61 PolarHBondContact O-N 3.36Å; E61-F63 PolarHBondContact O-N 3.34Å; E61-Y64 PolarHBondContact O-N 3.38Å
62A98.4Very high98.3Very high52 Ų5222.2 Ų22.243%0.4312%0.121SC..Hα-helixtrans-59.6-29.7-179.900000113V33 G58 V59 E60V33-A62 HydrophobicContact CB-CB 4.46Å; V33-A62 HydrophobicContact CG1-CB 3.98Å; V33-A62 HydrophobicContact CG2-CB 3.54Å; G58-A62 WeakPolarHBondContact O-CB 3.46Å; G58-A62 PolarHBondContact O-N 3.11Å; G58-A62 VanDerWaalsContact O-N 3.16Å; V59-A62 PolarHBondContact O-N 2.91Å; E60-A62 VanDerWaalsContact C-N 3.33Å; E60-A62 PolarHBondContact O-N 3.08Å
63F98.4Very high98.3Very high16 Ų1622.3 Ų22.37%0.0712%0.122CC..Hα-helixtrans-115.37.5-176.2-60.4-60.9000114.3V33 I36 L37 L40 V59 E60 E61 T65 T66 V69V33-F63 HydrophobicContact CB-CE2 4.39Å; V33-F63 HydrophobicContact CG1-CE2 4.39Å; V33-F63 HydrophobicContact CG1-CZ 4.12Å; V33-F63 HydrophobicContact CG2-CE2 3.96Å; V33-F63 HydrophobicContact CG2-CZ 4.49Å; I36-F63 HydrophobicContact CB-CE2 3.92Å; I36-F63 HydrophobicContact CB-CZ 3.71Å; I36-F63 HydrophobicContact CD1-CD2 4.42Å; I36-F63 HydrophobicContact CD1-CE2 3.76Å; I36-F63 HydrophobicContact CD1-CZ 4.44Å; I36-F63 HydrophobicContact CG1-CE2 4.44Å; I36-F63 HydrophobicContact CG2-CE1 3.93Å; I36-F63 HydrophobicContact CG2-CE2 3.72Å; I36-F63 HydrophobicContact CG2-CZ 3.36Å; L37-F63 HydrophobicContact CD2-CE1 4.15Å; L37-F63 HydrophobicContact CG-CZ 4.39Å; L40-F63 HydrophobicContact CD1-CE1 4.32Å; V59-F63 HydrophobicContact CG1-CD2 4.07Å; V59-F63 HydrophobicContact CG1-CE2 4.19Å; V59-F63 VanDerWaalsContact O-CD2 3.25Å; V59-F63 WeakPolarHBondContact O-CD2 3.37Å; V59-F63 PolarHBondContact O-N 3.27Å; E60-F63 CarbonylContact O-C 3.29Å; E60-F63 PolarHBondContact O-N 2.92Å; E60-F63 VanDerWaalsContact O-N 3.14Å; E61-F63 PolarHBondContact O-N 3.34Å; F63-T65 PolarHBondContact O-N 3.18Å; F63-T66 HydrophobicContact CB-CG2 3.84Å; F63-T66 HydrophobicContact CD1-CG2 3.89Å; F63-T66 HydrophobicContact CG-CG2 4.32Å; F63-T66 WeakPolarHBondContact O-CG2 3.38Å; F63-T66 PolarHBondContact O-N 3.16Å; F63-V69 HydrophobicContact CB-CB 3.88Å; F63-V69 HydrophobicContact CB-CG1 4.08Å; F63-V69 HydrophobicContact CB-CG2 4.46Å; F63-V69 HydrophobicContact CD1-CB 3.96Å; F63-V69 HydrophobicContact CD1-CG1 4.41Å; F63-V69 HydrophobicContact CD1-CG2 3.57Å; F63-V69 HydrophobicContact CD2-CB 4.24Å; F63-V69 HydrophobicContact CD2-CG1 3.81Å; F63-V69 HydrophobicContact CD2-CG2 4.35Å; F63-V69 HydrophobicContact CE1-CG2 3.84Å; F63-V69 HydrophobicContact CE2-CG1 4.39Å; F63-V69 HydrophobicContact CG-CB 3.75Å; F63-V69 HydrophobicContact CG-CG1 3.83Å; F63-V69 HydrophobicContact CG-CG2 3.86Å; F63-V69 HydrophobicContact CZ-CG2 4.36Å
64Y98.4Very high98.3Very high64 Ų6422.3 Ų22.325%0.25112%0.122SC..THydrogen-bonded Turntrans-57.3-23.8-171.9-157.9-107.3000114.6E60 E61 G91 A92 A99E60-Y64 HydrophobicContact CG-CD2 3.69Å; E60-Y64 HydrophobicContact CG-CE2 4.13Å; E60-Y64 WeakPolarHBondContact O-CA 3Å; E60-Y64 WeakPolarHBondContact O-CB 3.31Å; E60-Y64 PolarHBondContact O-N 3.14Å; E61-Y64 PolarHBondContact O-N 3.38Å; Y64-G91 VanDerWaalsContact CZ-CA 3.42Å; Y64-G91 CarbonylContact O-C 3.53Å; Y64-G91 VanDerWaalsContact O-CA 3.31Å; Y64-G91 WeakPolarHBondContact O-CA 3.46Å; Y64-A92 HydrophobicContact CD1-CB 3.84Å; Y64-A92 HydrophobicContact CE1-CB 3.8Å; Y64-A92 PolarHBondContact O-N 2.83Å; Y64-A99 HydrophobicContact CD2-CB 4.47Å; Y64-A99 HydrophobicContact CE2-CB 4.35Å
65T97.7Very high98.3Very high94 Ų9421.9 Ų21.958%0.57712%0.12SC*.THydrogen-bonded Turntrans-110.54.4-175.860.80000114.7F63 A92 G95F63-T65 PolarHBondContact O-N 3.18Å; T65-A92 VanDerWaalsContact CA-O 3.32Å; T65-A92 WeakPolarHBondContact CA-O 3.37Å; T65-A92 HydrophobicContact CG2-CB 4.33Å; T65-G95 VanDerWaalsContact C-N 3.31Å; T65-G95 PolarHBondContact O-N 2.91Å; T65-G95 VanDerWaalsContact O-N 3.1Å
66T96.3Very high98.3Very high37 Ų3723 Ų2323%0.22713%0.125CC..  trans-109.9149.5-179.1-166.90000112.8F63 R68 V69 G95F63-T66 HydrophobicContact CB-CG2 3.84Å; F63-T66 HydrophobicContact CD1-CG2 3.89Å; F63-T66 HydrophobicContact CG-CG2 4.32Å; F63-T66 WeakPolarHBondContact O-CG2 3.38Å; F63-T66 PolarHBondContact O-N 3.16Å; T66-R68 PolarHBondContact OG1-N 3.37Å; T66-V69 HydrophobicContact CG2-CB 4.15Å; T66-V69 HydrophobicContact CG2-CG2 4.28Å; T66-G95 VanDerWaalsContact C-CA 3.49Å; T66-G95 WeakPolarHBondContact O-CA 3.28Å
67D96.4Very high98.3Very high17 Ų1726.6 Ų26.69%0.09114%0.138CC..SBendtrans-96.1-2.7173.956.912.6000112R94 Y98 Y128 P253D67-R94 IonicContact OD1-NH2 3.35Å; D67-R94 PolarHBondContact OD1-NH2 2.87Å; D67-R94 IonicContact OD2-CZ 3.44Å; D67-R94 IonicContact OD2-NE 3.17Å; D67-R94 PolarHBondContact OD2-NE 2.84Å; D67-R94 VanDerWaalsContact OD2-NE 3.17Å; D67-R94 IonicContact OD2-NH2 2.81Å; D67-R94 PolarHBondContact OD2-NH2 2.79Å; D67-Y98 HydrophobicContact CB-CD2 4.2Å; D67-Y98 HydrophobicContact CB-CE1 4.13Å; D67-Y98 HydrophobicContact CB-CE2 3.68Å; D67-Y128 VanDerWaalsContact O-CE2 3.32Å; D67-Y128 WeakPolarHBondContact O-CE2 3.42Å; D67-Y128 PolarHBondContact O-OH 2.91Å; D67-P253 HydrophobicContact CB-CB 4.22Å; D67-P253 HydrophobicContact CB-CG 3.9Å; D67-P253 VanDerWaalsContact O-CG 3.28Å; D67-P253 WeakPolarHBondContact O-CG 3.42Å
68R97.1Very high98.1Very high29 Ų2927.8 Ų27.811%0.10915%0.153CC..SBendtrans-89.9-8.6-179.2-64.1-168.564.6-158.8-4.8114.5L40 F43 Q44 R45 V46 T66 Y128 V255L40-R68 HydrophobicContact CD2-CB 3.91Å; L40-R68 WeakPolarHBondContact CD2-O 3.42Å; L40-R68 PolarHBondContact O-NH2 3.28Å; F43-R68 PolarHBondContact O-NH2 3.42Å; Q44-R68 VanDerWaalsContact NE2-NE 3.16Å; Q44-R68 PolarHBondContact O-NE 3.35Å; R45-R68 WeakPolarHBondContact CA-O 3.44Å; V46-R68 PolarHBondContact N-O 3.5Å; V46-R68 VanDerWaalsContact N-O 3.1Å; T66-R68 PolarHBondContact OG1-N 3.37Å; R68-Y128 WeakPolarHBondContact CA-OH 3.37Å; R68-Y128 PolarHBondContact O-OH 3.22Å; R68-V255 HydrophobicContact CG-CG2 4.21Å
69V98.4Very high97.8Very high1 Ų137.2 Ų37.21%0.00620%0.197CC..EExtended strand (participates in β ladder)trans-133.3130.8172-1760000107.7I36 L40 V46 F63 T66 Y128I36-V69 HydrophobicContact CD1-CG1 4.41Å; I36-V69 HydrophobicContact CG2-CG1 4.17Å; I36-V69 HydrophobicContact CG2-CG2 3.54Å; L40-V69 HydrophobicContact CD1-CG2 3.75Å; L40-V69 HydrophobicContact CD2-CG2 4.2Å; L40-V69 HydrophobicContact CG-CG2 4.35Å; V46-V69 HydrophobicContact CB-CG2 4.47Å; V46-V69 WeakPolarHBondContact O-CA 3.42Å; F63-V69 HydrophobicContact CB-CB 3.88Å; F63-V69 HydrophobicContact CB-CG1 4.08Å; F63-V69 HydrophobicContact CB-CG2 4.46Å; F63-V69 HydrophobicContact CD1-CB 3.96Å; F63-V69 HydrophobicContact CD1-CG1 4.41Å; F63-V69 HydrophobicContact CD1-CG2 3.57Å; F63-V69 HydrophobicContact CD2-CB 4.24Å; F63-V69 HydrophobicContact CD2-CG1 3.81Å; F63-V69 HydrophobicContact CD2-CG2 4.35Å; F63-V69 HydrophobicContact CE1-CG2 3.84Å; F63-V69 HydrophobicContact CE2-CG1 4.39Å; F63-V69 HydrophobicContact CG-CB 3.75Å; F63-V69 HydrophobicContact CG-CG1 3.83Å; F63-V69 HydrophobicContact CG-CG2 3.86Å; F63-V69 HydrophobicContact CZ-CG2 4.36Å; T66-V69 HydrophobicContact CG2-CB 4.15Å; T66-V69 HydrophobicContact CG2-CG2 4.28Å; V69-Y128 WeakPolarHBondContact CA-OH 3.27Å; V69-Y128 PolarHBondContact N-OH 3.31Å; V69-Y128 VanDerWaalsContact N-OH 3.13Å
70M98.7Very high97.7Very high0 Ų039.2 Ų39.20%020%0.204CC..EExtended strand (participates in β ladder)trans-105.5127.1167.9174.4177.5-78.600108.4V46 L47 Y48 Y98 V100 A124 Y128 L246 M249V46-M70 PolarHBondContact O-N 3.44Å; L47-M70 HydrophobicContact CD1-CB 3.95Å; L47-M70 HydrophobicContact CD1-CG 3.75Å; L47-M70 HydrophobicContact CD1-SD 3.87Å; Y48-M70 PolarHBondContact N-O 3.22Å; M70-Y98 CarbonylContact C-O 3.6Å; M70-Y98 VanDerWaalsContact CA-O 3.23Å; M70-Y98 WeakPolarHBondContact CA-O 3.35Å; M70-Y98 HydrophobicContact CB-CD1 4.49Å; M70-Y98 HydrophobicContact CE-CD1 4.14Å; M70-Y98 WeakPolarHBondContact CG-O 3.1Å; M70-V100 HydrophobicContact CG-CG2 4.32Å; M70-V100 HydrophobicContact SD-CG2 4.34Å; M70-A124 HydrophobicContact SD-CB 3.88Å; M70-Y128 HydrophobicContact CB-CD1 3.63Å; M70-Y128 HydrophobicContact CB-CD2 4.29Å; M70-Y128 HydrophobicContact CB-CE1 3.59Å; M70-Y128 HydrophobicContact CB-CE2 4.27Å; M70-Y128 HydrophobicContact CB-CG 4Å; M70-Y128 HydrophobicContact CE-CD1 4.47Å; M70-Y128 HydrophobicContact CE-CD2 3.93Å; M70-Y128 HydrophobicContact CE-CG 3.75Å; M70-Y128 HydrophobicContact SD-CD1 4.19Å; M70-Y128 HydrophobicContact SD-CG 4Å; M70-L246 HydrophobicContact CE-CD2 4.13Å; M70-M249 HydrophobicContact CE-CE 3.77Å; M70-M249 HydrophobicContact CE-SD 3.13Å; M70-M249 WeakPolarHBondContact CE-SD 3.4Å
71T98.9Very high97.7Very high7 Ų742.9 Ų42.94%0.04322%0.22CC..EExtended strand (participates in β ladder)trans-97.8135.5170.858.60000109.9Y48 V59 E60 Y98 A99 V100Y48-T71 HydrophobicContact CD1-CG2 3.98Å; V59-T71 HydrophobicContact CG1-CG2 4.32Å; E60-T71 HydrophobicContact CB-CG2 4.5Å; T71-Y98 PolarHBondContact N-O 3.25Å; T71-A99 WeakPolarHBondContact OG1-CA 3.37Å; T71-V100 WeakPolarHBondContact O-CB 3.43Å; T71-V100 PolarHBondContact O-N 2.85Å
72L98.9Very high97.7Very high0 Ų039.2 Ų39.20%021%0.206CC..EExtended strand (participates in β ladder)trans-136106.7177.8174.463.2000109.1L47 Y48 V49 D50 F74 V100 I120 V121 A124L47-L72 HydrophobicContact CD1-CB 4.28Å; Y48-L72 PolarHBondContact O-N 3.3Å; V49-L72 CarbonylContact C-O 3.58Å; V49-L72 WeakPolarHBondContact CA-O 3.29Å; V49-L72 HydrophobicContact CG2-CD2 4.46Å; D50-L72 PolarHBondContact N-O 3.33Å; L72-F74 HydrophobicContact CD1-CE2 3.88Å; L72-F74 HydrophobicContact CD1-CZ 4.04Å; L72-F74 HydrophobicContact CD2-CE2 3.93Å; L72-F74 HydrophobicContact CD2-CZ 4.31Å; L72-F74 HydrophobicContact CG-CD2 4.43Å; L72-F74 HydrophobicContact CG-CE2 3.66Å; L72-F74 HydrophobicContact CG-CZ 4.24Å; L72-V100 VanDerWaalsContact CA-O 3.32Å; L72-V100 WeakPolarHBondContact CA-O 3.48Å; L72-V100 HydrophobicContact CB-CB 4.43Å; L72-V100 HydrophobicContact CD1-CB 3.64Å; L72-V100 HydrophobicContact CD1-CG1 3.42Å; L72-V100 VanDerWaalsContact CD1-CG1 3.42Å; L72-I120 HydrophobicContact CD1-CG2 3.7Å; L72-I120 HydrophobicContact CD2-CG2 4.4Å; L72-V121 HydrophobicContact CD2-CB 4.31Å; L72-V121 HydrophobicContact CD2-CG2 3.61Å; L72-A124 HydrophobicContact CD2-CB 4.23Å
73S98.9Very high97.6Very high3 Ų338.8 Ų38.82%0.02121%0.207CC..EExtended strand (participates in β ladder)trans-122.9138.4-175.5-176.80000111.9H75 V100 F102S73-H75 WeakPolarHBondContact CB-ND1 3.29Å; S73-H75 PolarHBondContact OG-ND1 3.46Å; S73-V100 PolarHBondContact N-O 3.36Å; S73-F102 PolarHBondContact O-N 2.9Å
74F98.9Very high97.6Very high0 Ų040.6 Ų40.60%022%0.219CC..EExtended strand (participates in β ladder)trans-120.589.7178.5-63.9-98.8000110.1D50 L72 F102 L104 Y113 I116 F117 I120 V121D50-F74 PolarHBondContact O-N 2.8Å; L72-F74 HydrophobicContact CD1-CE2 3.88Å; L72-F74 HydrophobicContact CD1-CZ 4.04Å; L72-F74 HydrophobicContact CD2-CE2 3.93Å; L72-F74 HydrophobicContact CD2-CZ 4.31Å; L72-F74 HydrophobicContact CG-CD2 4.43Å; L72-F74 HydrophobicContact CG-CE2 3.66Å; L72-F74 HydrophobicContact CG-CZ 4.24Å; F74-F102 HydrophobicContact CD1-CB 3.48Å; F74-F102 VanDerWaalsContact CD1-CB 3.48Å; F74-F102 AromaticContact CD1-CD2 3.89Å; F74-F102 HydrophobicContact CD1-CD2 3.89Å; F74-F102 AromaticContact CD1-CG 3.71Å; F74-F102 HydrophobicContact CD1-CG 3.71Å; F74-F102 HydrophobicContact CE1-CB 3.91Å; F74-F102 AromaticContact CE1-CD2 3.62Å; F74-F102 HydrophobicContact CE1-CD2 3.62Å; F74-F102 HydrophobicContact CE1-CE2 4.47Å; F74-F102 AromaticContact CE1-CG 3.95Å; F74-F102 HydrophobicContact CE1-CG 3.95Å; F74-F102 HydrophobicContact CG-CB 4.09Å; F74-L104 HydrophobicContact CB-CD1 4.29Å; F74-Y113 HydrophobicContact CB-CE2 4.08Å; F74-Y113 VanDerWaalsContact CB-OH 3.24Å; F74-Y113 WeakPolarHBondContact CB-OH 3.48Å; F74-I116 HydrophobicContact CD1-CD1 4.32Å; F74-F117 AromaticContact CD2-CD2 3.83Å; F74-F117 HydrophobicContact CD2-CD2 3.83Å; F74-F117 HydrophobicContact CD2-CE2 4.08Å; F74-F117 HydrophobicContact CE1-CD2 4.34Å; F74-F117 AromaticContact CE2-CD2 3.52Å; F74-F117 HydrophobicContact CE2-CD2 3.52Å; F74-F117 AromaticContact CE2-CE2 3.8Å; F74-F117 HydrophobicContact CE2-CE2 3.8Å; F74-F117 HydrophobicContact CG-CD2 4.37Å; F74-F117 HydrophobicContact CZ-CB 4.5Å; F74-F117 AromaticContact CZ-CD2 3.81Å; F74-F117 HydrophobicContact CZ-CD2 3.81Å; F74-F117 HydrophobicContact CZ-CE2 4.48Å; F74-F117 HydrophobicContact CZ-CG 4.44Å; F74-I120 HydrophobicContact CE1-CB 4.41Å; F74-I120 HydrophobicContact CE1-CG2 4.46Å; F74-I120 HydrophobicContact CZ-CB 4.11Å; F74-I120 HydrophobicContact CZ-CG2 3.97Å; F74-V121 HydrophobicContact CE2-CG2 4.12Å; F74-V121 HydrophobicContact CZ-CG2 4.17Å
75H98.8Very high97.6Very high0 Ų037.6 Ų37.60%021%0.207CC..EExtended strand (participates in β ladder)trans-131.1162.5-166.751-97.9000111.6C53 H54 H55 S73 G85 F102 L104C53-H75 CarbonylContact O-C 3.52Å; C53-H75 WeakPolarHBondContact O-CA 3.13Å; C53-H75 WeakPolarHBondContact O-CB 3.41Å; H54-H75 VanDerWaalsContact C-CB 3.49Å; H55-H75 HydrophobicContact CB-CB 4.35Å; H55-H75 AromaticContact CD2-CE1 3.32Å; H55-H75 PolarHBondContact CD2-CE1 3.47Å; H55-H75 AromaticContact CD2-ND1 3.57Å; H55-H75 AromaticContact CG-CE1 3.64Å; H55-H75 AromaticContact CG-ND1 3.91Å; H55-H75 AromaticContact CG-NE2 3.96Å; S73-H75 WeakPolarHBondContact CB-ND1 3.29Å; S73-H75 PolarHBondContact OG-ND1 3.46Å; H75-G85 PolarHBondContact NE2-O 3.34Å; H75-G85 VanDerWaalsContact NE2-O 3.09Å; H75-F102 PolarHBondContact N-O 2.88Å; H75-L104 WeakPolarHBondContact O-CA 3.42Å; H75-L104 VanDerWaalsContact O-CB 3.32Å; H75-L104 WeakPolarHBondContact O-CB 3.44Å; H75-L104 PolarHBondContact O-N 2.86Å
76K98.4Very high97.6Very high26 Ų2634.9 Ų34.911%0.11319%0.189CC..EExtended strand (participates in β ladder)trans-69.1135.6168.2174.7170.1-177.3-67.20110.4C53 Y80 L104 D106 C149 L150C53-K76 PolarHBondContact O-N 3.47Å; K76-Y80 HydrophobicContact CB-CD1 3.72Å; K76-Y80 HydrophobicContact CB-CE1 3.91Å; K76-Y80 HydrophobicContact CB-CG 4.33Å; K76-Y80 HydrophobicContact CD-CD1 3.85Å; K76-Y80 HydrophobicContact CD-CD2 3.77Å; K76-Y80 HydrophobicContact CD-CE1 4.08Å; K76-Y80 HydrophobicContact CD-CE2 4Å; K76-Y80 HydrophobicContact CD-CG 3.68Å; K76-Y80 HydrophobicContact CG-CD1 3.76Å; K76-Y80 HydrophobicContact CG-CD2 4.44Å; K76-Y80 HydrophobicContact CG-CE1 4.27Å; K76-Y80 HydrophobicContact CG-CG 3.85Å; K76-Y80 VanDerWaalsContact NZ-CB 3.26Å; K76-Y80 VanDerWaalsContact NZ-CG 3.33Å; K76-L104 WeakPolarHBondContact CA-O 3.48Å; K76-D106 WeakPolarHBondContact CD-OD1 3.34Å; K76-D106 WeakPolarHBondContact CE-OD1 3.42Å; K76-C149 WeakPolarHBondContact CD-SG 3.2Å; K76-C149 WeakPolarHBondContact CE-SG 3.38Å; K76-L150 HydrophobicContact CB-CD2 4.39Å
77Y98.1Very high97.7Very high77 Ų7734.7 Ų34.730%0.30219%0.187SC..  trans-125.6154.5177.6179.8-107.9000112.4T84 D86 P103 L104Y77-T84 WeakPolarHBondContact CD2-O 3.33Å; Y77-D86 HydrophobicContact CE1-CB 4.2Å; Y77-D86 WeakPolarHBondContact CE1-OD2 3.31Å; Y77-D86 HydrophobicContact CE2-CB 4.1Å; Y77-D86 WeakPolarHBondContact OH-CB 3.43Å; Y77-D86 PolarHBondContact OH-OD2 2.84Å; Y77-P103 HydrophobicContact CD1-CB 3.87Å; Y77-P103 HydrophobicContact CG-CB 3.81Å; Y77-L104 PolarHBondContact N-O 2.95Å
78G94.7Very high97.7Very high38 Ų3841.9 Ų41.939%0.39222%0.217SC..SBendtrans122.4-139.7-178.700000111.6Y80G78-Y80 PolarHBondContact O-N 2.94Å
79E93.6Very high97.8Very high201 Ų20142.8 Ų42.894%0.93922%0.224SC*.SBendtrans-71.975.1170-65.8178.8-176.400109.5
80Y96.3Very high97.8Very high42 Ų4244.3 Ų44.317%0.16523%0.232CC..SBendtrans-156.8145.6-177.3-157.1-118.9000109.5C53 H54 K76 G78 G83 L147 G148C53-Y80 PolarHBondContact SG-OH 3Å; H54-Y80 AromaticContact CD2-CE1 3.46Å; H54-Y80 VanDerWaalsContact CD2-CE1 3.46Å; H54-Y80 WeakPolarHBondContact CD2-CE1 3.43Å; H54-Y80 AromaticContact CD2-CZ 3.99Å; H54-Y80 AromaticContact NE2-CE1 3.7Å; H54-Y80 AromaticContact NE2-CZ 3.73Å; H54-Y80 PolarHBondContact NE2-OH 2.88Å; K76-Y80 HydrophobicContact CB-CD1 3.72Å; K76-Y80 HydrophobicContact CB-CE1 3.91Å; K76-Y80 HydrophobicContact CB-CG 4.33Å; K76-Y80 HydrophobicContact CD-CD1 3.85Å; K76-Y80 HydrophobicContact CD-CD2 3.77Å; K76-Y80 HydrophobicContact CD-CE1 4.08Å; K76-Y80 HydrophobicContact CD-CE2 4Å; K76-Y80 HydrophobicContact CD-CG 3.68Å; K76-Y80 HydrophobicContact CG-CD1 3.76Å; K76-Y80 HydrophobicContact CG-CD2 4.44Å; K76-Y80 HydrophobicContact CG-CE1 4.27Å; K76-Y80 HydrophobicContact CG-CG 3.85Å; K76-Y80 VanDerWaalsContact NZ-CB 3.26Å; K76-Y80 VanDerWaalsContact NZ-CG 3.33Å; G78-Y80 PolarHBondContact O-N 2.94Å; Y80-G83 WeakPolarHBondContact O-CA 3.23Å; Y80-G83 PolarHBondContact O-N 3.04Å; Y80-L147 PolarHBondContact OH-O 3.35Å; Y80-G148 WeakPolarHBondContact OH-CA 3.44Å
81F97.8Very high97.8Very high89 Ų8944.7 Ų44.739%0.3924%0.236SC..THydrogen-bonded Turntrans-63.9139.2175.6-177.8-96.7000110.5H17 H54H17-F81 AromaticContact CD2-CE1 3.67Å; H17-F81 AromaticContact CE1-CE1 3.62Å; H17-F81 AromaticContact CG-CE1 3.87Å; H17-F81 AromaticContact ND1-CE1 3.83Å; H17-F81 AromaticContact NE2-CE1 3.47Å; H17-F81 WeakPolarHBondContact NE2-CE1 3.41Å; H54-F81 PolarHBondContact CD2-O 2.79Å
82P97.8Very high97.7Very high31 Ų3146.2 Ų46.220%0.20125%0.249CC..THydrogen-bonded Turncis-89.44.4-2.135.6-36.1000114.9H55 D57 T84H55-P82 HydrophobicContact CB-CG 4.02Å; D57-P82 HydrophobicContact CB-CG 3.93Å; P82-T84 VanDerWaalsContact C-N 3.33Å; P82-T84 WeakPolarHBondContact CG-OG1 3.29Å
83G96.9Very high97.6Very high43 Ų4349.6 Ų49.644%0.44328%0.284SS..  trans79.812.6-179.400000114.5Y80Y80-G83 WeakPolarHBondContact O-CA 3.23Å; Y80-G83 PolarHBondContact O-N 3.04Å
84T98.1Very high97.4Very high54 Ų5456.8 Ų56.833%0.33131%0.311SS..  trans-117.2177.3176.661.80000110.6H55 D57 Y77 P82H55-T84 VanDerWaalsContact ND1-C 3.32Å; H55-T84 PolarHBondContact ND1-OG1 3.28Å; D57-T84 VanDerWaalsContact CB-OG1 3.31Å; D57-T84 WeakPolarHBondContact CB-OG1 3.17Å; Y77-T84 WeakPolarHBondContact CD2-O 3.33Å; P82-T84 VanDerWaalsContact C-N 3.33Å; P82-T84 WeakPolarHBondContact CG-OG1 3.29Å
85G98.1Very high97.3Very high0 Ų056.8 Ų56.80%031%0.311CS..  trans89.333.2-179.200000112.4H55 H75 D89 N101H55-G85 VanDerWaalsContact CE1-CA 3.46Å; H55-G85 WeakPolarHBondContact CE1-CA 3.49Å; H55-G85 PolarHBondContact CE1-N 2.97Å; H55-G85 WeakPolarHBondContact ND1-CA 3.4Å; H55-G85 PolarHBondContact ND1-N 2.77Å; H75-G85 PolarHBondContact NE2-O 3.34Å; H75-G85 VanDerWaalsContact NE2-O 3.09Å; G85-D89 PolarHBondContact N-OD2 2.92Å; G85-N101 WeakPolarHBondContact O-CB 3.37Å
86D98Very high97.3Very high37 Ų3761.5 Ų61.520%0.19833%0.331CS..  trans-63.3152.2172.6-164.7-65.9000109.5Y77 K88 D89Y77-D86 HydrophobicContact CE1-CB 4.2Å; Y77-D86 WeakPolarHBondContact CE1-OD2 3.31Å; Y77-D86 HydrophobicContact CE2-CB 4.1Å; Y77-D86 WeakPolarHBondContact OH-CB 3.43Å; Y77-D86 PolarHBondContact OH-OD2 2.84Å; D86-K88 PolarHBondContact O-N 3Å; D86-K88 WeakPolarHBondContact OD1-CG 3.45Å; D86-K88 PolarHBondContact OD1-N 3.02Å; D86-D89 PolarHBondContact N-OD2 2.89Å; D86-D89 WeakPolarHBondContact O-CB 3.35Å; D86-D89 PolarHBondContact O-N 3.18Å
87L98.1Very high97.3Very high33 Ų3362.8 Ų62.817%0.17334%0.336CS..THydrogen-bonded Turntrans-53.8-21.9170.4-178.557.6000113.7P103 I238 K241 L242L87-P103 HydrophobicContact CB-CG 4.07Å; L87-I238 HydrophobicContact CD1-CG2 4.08Å; L87-I238 HydrophobicContact CD2-CG1 4.31Å; L87-K241 HydrophobicContact CD1-CB 4.28Å; L87-K241 HydrophobicContact CD1-CG 3.96Å; L87-K241 HydrophobicContact CD2-CB 4Å; L87-K241 HydrophobicContact CD2-CG 3.82Å; L87-K241 HydrophobicContact CG-CB 4.43Å; L87-K241 HydrophobicContact CG-CG 3.87Å; L87-L242 HydrophobicContact CD1-CD2 3.44Å; L87-L242 VanDerWaalsContact CD1-CD2 3.44Å; L87-L242 HydrophobicContact CD1-CG 3.83Å
88K98Very high97.3Very high168 Ų16859.4 Ų59.473%0.7332%0.323SS*.THydrogen-bonded Turntrans-85.4-15.1177-63.8173.2-169.81650113.7D86 I90D86-K88 PolarHBondContact O-N 3Å; D86-K88 WeakPolarHBondContact OD1-CG 3.45Å; D86-K88 PolarHBondContact OD1-N 3.02Å; K88-I90 PolarHBondContact O-N 3.05Å; K88-I90 VanDerWaalsContact O-N 3.11Å
89D98.2Very high97.5Very high49 Ų4957.8 Ų57.826%0.26231%0.306SS..  trans-78.196.9177.2-60-26.5000107.8G85 D86 N101G85-D89 PolarHBondContact N-OD2 2.92Å; D86-D89 PolarHBondContact N-OD2 2.89Å; D86-D89 WeakPolarHBondContact O-CB 3.35Å; D86-D89 PolarHBondContact O-N 3.18Å; D89-N101 PolarHBondContact O-ND2 3.33Å; D89-N101 VanDerWaalsContact O-ND2 3.09Å
90I98.4Very high97.7Very high32 Ų3248.5 Ų48.516%0.16426%0.263CS..  trans-120.314.8-169.962166.5000112.8K88 K96 Y97 N245K88-I90 PolarHBondContact O-N 3.05Å; K88-I90 VanDerWaalsContact O-N 3.11Å; I90-K96 HydrophobicContact CD1-CG 4.17Å; I90-K96 CarbonylContact O-C 3.51Å; I90-K96 WeakPolarHBondContact O-CA 3.43Å; I90-Y97 HydrophobicContact CD1-CD1 4.06Å; I90-Y97 HydrophobicContact CD1-CE1 3.81Å; I90-Y97 WeakPolarHBondContact O-CA 3.18Å; I90-Y97 PolarHBondContact O-N 3.08Å; I90-N245 WeakPolarHBondContact CG2-ND2 3.26Å
91G98.2Very high97.9Very high8 Ų846.6 Ų46.68%0.08226%0.255CS..  trans80.3171.6-172.800000113.1Y64Y64-G91 VanDerWaalsContact CZ-CA 3.42Å; Y64-G91 CarbonylContact O-C 3.53Å; Y64-G91 VanDerWaalsContact O-CA 3.31Å; Y64-G91 WeakPolarHBondContact O-CA 3.46Å
92A98Very high97.9Very high39 Ų3942.3 Ų42.332%0.32224%0.237SC..  trans-137.4161.3-175.900000112.5Y64 T65 R94 G95 K96Y64-A92 HydrophobicContact CD1-CB 3.84Å; Y64-A92 HydrophobicContact CE1-CB 3.8Å; Y64-A92 PolarHBondContact O-N 2.83Å; T65-A92 VanDerWaalsContact CA-O 3.32Å; T65-A92 WeakPolarHBondContact CA-O 3.37Å; T65-A92 HydrophobicContact CG2-CB 4.33Å; A92-R94 PolarHBondContact O-N 2.83Å; A92-G95 WeakPolarHBondContact O-CA 3.18Å; A92-G95 PolarHBondContact O-N 2.87Å; A92-K96 PolarHBondContact O-N 2.85Å
93G96.5Very high97.9Very high71 Ų7141.1 Ų41.173%0.73223%0.229SC*.G310 helixtrans56-123.2179.900000111.9G95G93-G95 VanDerWaalsContact C-N 3.34Å
94R95.3Very high98Very high154 Ų15439.1 Ų39.158%0.58121%0.208SC*.G310 helixtrans-71-29.1176.8-67.6179.860.1159.9-3.3113D67 A92 K96 Y98D67-R94 IonicContact OD1-NH2 3.35Å; D67-R94 PolarHBondContact OD1-NH2 2.87Å; D67-R94 IonicContact OD2-CZ 3.44Å; D67-R94 IonicContact OD2-NE 3.17Å; D67-R94 PolarHBondContact OD2-NE 2.84Å; D67-R94 VanDerWaalsContact OD2-NE 3.17Å; D67-R94 IonicContact OD2-NH2 2.81Å; D67-R94 PolarHBondContact OD2-NH2 2.79Å; A92-R94 PolarHBondContact O-N 2.83Å; R94-K96 PolarHBondContact O-N 3.17Å; R94-Y98 WeakPolarHBondContact O-CE2 3.27Å
95G96.8Very high98Very high1 Ų141.8 Ų41.81%0.0121%0.212CC..G310 helixtrans-80.55.5177.700000114.9T65 T66 A92 G93 Y97 Y98T65-G95 VanDerWaalsContact C-N 3.31Å; T65-G95 PolarHBondContact O-N 2.91Å; T65-G95 VanDerWaalsContact O-N 3.1Å; T66-G95 VanDerWaalsContact C-CA 3.49Å; T66-G95 WeakPolarHBondContact O-CA 3.28Å; A92-G95 WeakPolarHBondContact O-CA 3.18Å; A92-G95 PolarHBondContact O-N 2.87Å; G93-G95 VanDerWaalsContact C-N 3.34Å; G95-Y97 PolarHBondContact O-N 2.82Å; G95-Y98 WeakPolarHBondContact O-CB 3.45Å; G95-Y98 PolarHBondContact O-N 3.19Å
96K98Very high98Very high98 Ų9844.1 Ų44.143%0.42622%0.224SC..THydrogen-bonded Turntrans-60.6129.3174.2-169.7-177.9-179.6-177.80110.9I90 A92 R94 Y98I90-K96 HydrophobicContact CD1-CG 4.17Å; I90-K96 CarbonylContact O-C 3.51Å; I90-K96 WeakPolarHBondContact O-CA 3.43Å; A92-K96 PolarHBondContact O-N 2.85Å; R94-K96 PolarHBondContact O-N 3.17Å; K96-Y98 VanDerWaalsContact C-N 3.34Å; K96-Y98 VanDerWaalsContact O-CD2 3.3Å; K96-Y98 WeakPolarHBondContact O-CD2 3.37Å
97Y98.2Very high98Very high53 Ų5342.3 Ų42.321%0.20822%0.215CC..THydrogen-bonded Turntrans74.84-171-52.1-69.6000116.7I90 G95 N245 A248I90-Y97 HydrophobicContact CD1-CD1 4.06Å; I90-Y97 HydrophobicContact CD1-CE1 3.81Å; I90-Y97 WeakPolarHBondContact O-CA 3.18Å; I90-Y97 PolarHBondContact O-N 3.08Å; G95-Y97 PolarHBondContact O-N 2.82Å; Y97-N245 HydrophobicContact CD1-CB 3.97Å; Y97-N245 HydrophobicContact CE1-CB 4.44Å; Y97-A248 HydrophobicContact CD1-CB 4.38Å; Y97-A248 HydrophobicContact CD2-CB 4.43Å; Y97-A248 HydrophobicContact CE1-CB 3.98Å; Y97-A248 HydrophobicContact CE2-CB 4.04Å
98Y98.3Very high98.1Very high6 Ų640.8 Ų40.82%0.02421%0.207CC..  trans-98.8-5178-62.8-94000113.5D67 M70 T71 R94 G95 K96 Y128 M249 P250 P253D67-Y98 HydrophobicContact CB-CD2 4.2Å; D67-Y98 HydrophobicContact CB-CE1 4.13Å; D67-Y98 HydrophobicContact CB-CE2 3.68Å; M70-Y98 CarbonylContact C-O 3.6Å; M70-Y98 VanDerWaalsContact CA-O 3.23Å; M70-Y98 WeakPolarHBondContact CA-O 3.35Å; M70-Y98 HydrophobicContact CB-CD1 4.49Å; M70-Y98 HydrophobicContact CE-CD1 4.14Å; M70-Y98 WeakPolarHBondContact CG-O 3.1Å; T71-Y98 PolarHBondContact N-O 3.25Å; R94-Y98 WeakPolarHBondContact O-CE2 3.27Å; G95-Y98 WeakPolarHBondContact O-CB 3.45Å; G95-Y98 PolarHBondContact O-N 3.19Å; K96-Y98 VanDerWaalsContact C-N 3.34Å; K96-Y98 VanDerWaalsContact O-CD2 3.3Å; K96-Y98 WeakPolarHBondContact O-CD2 3.37Å; Y98-Y128 AromaticContact CD1-CD2 3.76Å; Y98-Y128 HydrophobicContact CD1-CD2 3.76Å; Y98-Y128 AromaticContact CD1-CE2 3.5Å; Y98-Y128 HydrophobicContact CD1-CE2 3.5Å; Y98-Y128 AromaticContact CE1-CD2 3.56Å; Y98-Y128 HydrophobicContact CE1-CD2 3.56Å; Y98-Y128 AromaticContact CE1-CE2 3.39Å; Y98-Y128 HydrophobicContact CE1-CE2 3.39Å; Y98-M249 HydrophobicContact CD1-CG 4.39Å; Y98-M249 HydrophobicContact CD1-SD 3.62Å; Y98-M249 HydrophobicContact CD2-CG 4.39Å; Y98-M249 HydrophobicContact CE1-CE 4.4Å; Y98-M249 HydrophobicContact CE1-CG 3.9Å; Y98-M249 HydrophobicContact CE1-SD 3.42Å; Y98-M249 WeakPolarHBondContact CE1-SD 3.27Å; Y98-M249 HydrophobicContact CE2-CG 3.94Å; Y98-M249 HydrophobicContact CE2-SD 4.4Å; Y98-M249 HydrophobicContact CG-SD 4.19Å; Y98-P250 PolarHBondContact OH-O 3.17Å; Y98-P253 HydrophobicContact CE1-CG 4.11Å; Y98-P253 WeakPolarHBondContact OH-CG 3.39Å
99A98.7Very high98.1Very high5 Ų534.8 Ų34.84%0.04118%0.184CC..EExtended strand (participates in β ladder)trans-98.5121.5163.900000109.6E60 Y64 T71E60-A99 HydrophobicContact CG-CB 4.27Å; E60-A99 WeakPolarHBondContact OE2-CB 3.47Å; Y64-A99 HydrophobicContact CD2-CB 4.47Å; Y64-A99 HydrophobicContact CE2-CB 4.35Å; T71-A99 WeakPolarHBondContact OG1-CA 3.37Å
100V98.8Very high98.1Very high5 Ų533.9 Ų33.93%0.0318%0.18CC..EExtended strand (participates in β ladder)trans-124.199.8-174.5-169.30000109.1M70 T71 L72 S73 I120 L242 L246M70-V100 HydrophobicContact CG-CG2 4.32Å; M70-V100 HydrophobicContact SD-CG2 4.34Å; T71-V100 WeakPolarHBondContact O-CB 3.43Å; T71-V100 PolarHBondContact O-N 2.85Å; L72-V100 VanDerWaalsContact CA-O 3.32Å; L72-V100 WeakPolarHBondContact CA-O 3.48Å; L72-V100 HydrophobicContact CB-CB 4.43Å; L72-V100 HydrophobicContact CD1-CB 3.64Å; L72-V100 HydrophobicContact CD1-CG1 3.42Å; L72-V100 VanDerWaalsContact CD1-CG1 3.42Å; S73-V100 PolarHBondContact N-O 3.36Å; V100-I120 HydrophobicContact CG1-CG2 4.44Å; V100-L242 HydrophobicContact CG1-CD1 4.29Å; V100-L242 HydrophobicContact CG1-CD2 3.92Å; V100-L246 HydrophobicContact CG2-CD2 4.12Å
101N98.9Very high98.1Very high2 Ų237.3 Ų37.31%0.01120%0.198CC..EExtended strand (participates in β ladder)trans-105.1123.3-177.4-68.3-51.7000111.9H55 E60 G85 D89 P103H55-N101 PolarHBondContact NE2-OD1 2.82Å; E60-N101 PolarHBondContact OE1-ND2 2.84Å; E60-N101 PolarHBondContact OE2-ND2 3.29Å; E60-N101 PolarHBondContact OE2-OD1 3.42Å; G85-N101 WeakPolarHBondContact O-CB 3.37Å; D89-N101 PolarHBondContact O-ND2 3.33Å; D89-N101 VanDerWaalsContact O-ND2 3.09Å; N101-P103 WeakPolarHBondContact O-CD 3.38Å
102F98.8Very high98.1Very high0 Ų038 Ų380%020%0.202CC..EExtended strand (participates in β ladder)trans-104.790.2173.3-155.1-54.6000109.5S73 F74 H75 L104 I116 I120 L235 I238 M239 L242S73-F102 PolarHBondContact O-N 2.9Å; F74-F102 HydrophobicContact CD1-CB 3.48Å; F74-F102 VanDerWaalsContact CD1-CB 3.48Å; F74-F102 AromaticContact CD1-CD2 3.89Å; F74-F102 HydrophobicContact CD1-CD2 3.89Å; F74-F102 AromaticContact CD1-CG 3.71Å; F74-F102 HydrophobicContact CD1-CG 3.71Å; F74-F102 HydrophobicContact CE1-CB 3.91Å; F74-F102 AromaticContact CE1-CD2 3.62Å; F74-F102 HydrophobicContact CE1-CD2 3.62Å; F74-F102 HydrophobicContact CE1-CE2 4.47Å; F74-F102 AromaticContact CE1-CG 3.95Å; F74-F102 HydrophobicContact CE1-CG 3.95Å; F74-F102 HydrophobicContact CG-CB 4.09Å; H75-F102 PolarHBondContact N-O 2.88Å; F102-L104 HydrophobicContact CD1-CD2 3.58Å; F102-L104 HydrophobicContact CD1-CG 4.33Å; F102-L104 HydrophobicContact CE1-CD2 3.81Å; F102-L104 PolarHBondContact O-N 2.69Å; F102-I116 HydrophobicContact CD1-CD1 4.07Å; F102-I116 HydrophobicContact CD2-CB 4.5Å; F102-I116 HydrophobicContact CE1-CD1 3.72Å; F102-I116 HydrophobicContact CE2-CB 3.7Å; F102-I116 HydrophobicContact CE2-CD1 4.19Å; F102-I116 HydrophobicContact CE2-CG1 4.41Å; F102-I116 HydrophobicContact CE2-CG2 4.11Å; F102-I116 HydrophobicContact CG-CD1 4.47Å; F102-I116 HydrophobicContact CZ-CB 3.73Å; F102-I116 HydrophobicContact CZ-CD1 3.8Å; F102-I116 HydrophobicContact CZ-CG1 4.33Å; F102-I116 HydrophobicContact CZ-CG2 3.69Å; F102-I120 HydrophobicContact CD2-CG1 4.17Å; F102-I120 HydrophobicContact CE2-CG1 4.07Å; F102-L235 HydrophobicContact CE1-CD2 3.75Å; F102-L235 HydrophobicContact CZ-CD2 4.11Å; F102-I238 HydrophobicContact CD1-CD1 4.29Å; F102-I238 HydrophobicContact CD1-CG2 3.75Å; F102-I238 HydrophobicContact CD2-CG2 3.97Å; F102-I238 HydrophobicContact CE1-CB 3.93Å; F102-I238 HydrophobicContact CE1-CD1 3.88Å; F102-I238 HydrophobicContact CE1-CG2 3.59Å; F102-I238 HydrophobicContact CE2-CB 4.48Å; F102-I238 HydrophobicContact CE2-CG2 3.82Å; F102-I238 HydrophobicContact CG-CG2 3.92Å; F102-I238 HydrophobicContact CZ-CB 3.89Å; F102-I238 HydrophobicContact CZ-CG2 3.62Å; F102-M239 HydrophobicContact CE2-CG 3.82Å; F102-M239 HydrophobicContact CZ-CG 4Å; F102-L242 HydrophobicContact CB-CD1 4.11Å; F102-L242 HydrophobicContact CD2-CD1 3.43Å; F102-L242 VanDerWaalsContact CD2-CD1 3.43Å; F102-L242 HydrophobicContact CE2-CD1 4.06Å; F102-L242 HydrophobicContact CG-CD1 4.01Å
103P98.6Very high98.1Very high6 Ų636.3 Ų36.34%0.03919%0.187CC..EExtended strand (participates in β ladder)trans-69.1122.6178.426.6-34.1000110.6Y77 L87 N101 Y234 I238Y77-P103 HydrophobicContact CD1-CB 3.87Å; Y77-P103 HydrophobicContact CG-CB 3.81Å; L87-P103 HydrophobicContact CB-CG 4.07Å; N101-P103 WeakPolarHBondContact O-CD 3.38Å; P103-Y234 PolarHBondContact O-OH 3.36Å; P103-I238 HydrophobicContact CG-CD1 3.99Å; P103-I238 WeakPolarHBondContact O-CD1 3.5Å
104L98.8Very high98.2Very high0 Ų035.7 Ų35.70%017%0.165CC..EExtended strand (participates in β ladder)trans-105.1162.2178.1-58.1173.9000110.8F74 H75 K76 Y77 F102 I108 Y113 I116 L150 L235F74-L104 HydrophobicContact CB-CD1 4.29Å; H75-L104 WeakPolarHBondContact O-CA 3.42Å; H75-L104 VanDerWaalsContact O-CB 3.32Å; H75-L104 WeakPolarHBondContact O-CB 3.44Å; H75-L104 PolarHBondContact O-N 2.86Å; K76-L104 WeakPolarHBondContact CA-O 3.48Å; Y77-L104 PolarHBondContact N-O 2.95Å; F102-L104 HydrophobicContact CD1-CD2 3.58Å; F102-L104 HydrophobicContact CD1-CG 4.33Å; F102-L104 HydrophobicContact CE1-CD2 3.81Å; F102-L104 PolarHBondContact O-N 2.69Å; L104-I108 HydrophobicContact CD1-CG2 4.29Å; L104-Y113 HydrophobicContact CD1-CD2 4.21Å; L104-Y113 HydrophobicContact CD1-CE2 3.81Å; L104-I116 HydrophobicContact CD2-CD1 3.57Å; L104-L150 HydrophobicContact CB-CD2 4.42Å; L104-L150 HydrophobicContact CD1-CD1 4.22Å; L104-L235 HydrophobicContact CD2-CD2 4.29Å
105R98.4Very high98.4Very high111 Ų11135.2 Ų35.242%0.41917%0.167SC..  trans-111.3172169.4-61.4175.6175.2-174.3-5.1109.7Q229 N230 Y234R105-Q229 HydrophobicContact CB-CB 3.79Å; R105-Q229 VanDerWaalsContact CD-O 3.31Å; R105-Q229 WeakPolarHBondContact CD-O 3.29Å; R105-N230 PolarHBondContact N-OD1 3.3Å; R105-N230 PolarHBondContact O-ND2 3.48Å; R105-Y234 HydrophobicContact CG-CE1 3.87Å
106D98Very high98.4Very high48 Ų4835.3 Ų35.326%0.25717%0.167SC..THydrogen-bonded Turntrans-54.1147.8-179.4-53.6-20.7000113K76 I108 C149 Q229 N230K76-D106 WeakPolarHBondContact CD-OD1 3.34Å; K76-D106 WeakPolarHBondContact CE-OD1 3.42Å; D106-I108 PolarHBondContact O-N 3.25Å; D106-C149 WeakPolarHBondContact CA-O 3.38Å; D106-C149 PolarHBondContact OD1-SG 2.7Å; D106-Q229 HydrophobicContact CB-CG 4.31Å; D106-Q229 PolarHBondContact O-N 2.6Å; D106-Q229 PolarHBondContact OD2-NE2 3.4Å; D106-N230 PolarHBondContact O-ND2 2.97Å
107G98Very high98.5Very high0 Ų030.7 Ų30.70%015%0.147CC..THydrogen-bonded Turntrans72.920.9166.100000115.3T109 C149 N228G107-T109 PolarHBondContact O-N 3.11Å; G107-C149 PolarHBondContact N-O 2.88Å; G107-N228 VanDerWaalsContact O-CA 3.29Å; G107-N228 WeakPolarHBondContact O-CA 3.22Å; G107-N228 WeakPolarHBondContact O-CB 3.49Å; G107-N228 PolarHBondContact O-OD1 3.17Å
108I98.6Very high98.5Very high0 Ų031.1 Ų31.10%015%0.151CC..  trans-53.9131.1171.3-16669.9000109.4L104 D106 Y113 L150 N151 L152 N230 L235L104-I108 HydrophobicContact CD1-CG2 4.29Å; D106-I108 PolarHBondContact O-N 3.25Å; I108-Y113 HydrophobicContact CG1-CD2 3.98Å; I108-Y113 HydrophobicContact CG2-CD2 4Å; I108-L150 HydrophobicContact CG2-CB 3.88Å; I108-L150 HydrophobicContact CG2-CD1 4.06Å; I108-L150 HydrophobicContact CG2-CD2 3.76Å; I108-L150 HydrophobicContact CG2-CG 4.08Å; I108-N151 CarbonylContact O-C 3.52Å; I108-N151 VanDerWaalsContact O-CA 3.26Å; I108-N151 WeakPolarHBondContact O-CA 3.26Å; I108-N151 WeakPolarHBondContact O-CB 3.32Å; I108-N151 PolarHBondContact O-N 3.47Å; I108-L152 HydrophobicContact CG2-CD2 4.18Å; I108-N230 WeakPolarHBondContact CB-ND2 3.32Å; I108-N230 HydrophobicContact CD1-CB 3.54Å; I108-N230 PolarHBondContact N-ND2 2.76Å; I108-L235 HydrophobicContact CD1-CD1 4.06Å; I108-L235 HydrophobicContact CD1-CD2 4.36Å
109T98.4Very high98.5Very high43 Ų4333.2 Ų33.226%0.26417%0.166SC..BIsolated β-bridgetrans-102.3160-178.256.30000111G107 D111 S112 Y113 N228G107-T109 PolarHBondContact O-N 3.11Å; T109-D111 VanDerWaalsContact C-N 3.3Å; T109-D111 PolarHBondContact O-N 3.09Å; T109-S112 PolarHBondContact O-N 3.24Å; T109-Y113 WeakPolarHBondContact O-CB 3.34Å; T109-Y113 PolarHBondContact O-N 2.76Å; T109-N228 HydrophobicContact CG2-CB 4.33Å; T109-N228 PolarHBondContact OG1-ND2 2.99Å
110D98.3Very high98.5Very high30 Ų3033 Ų3316%0.1616%0.164CC..Hα-helixtrans-44.3-51.5176.7-65.1-3.2000113.2S112 Y113 E114 L152 T153 G156D110-S112 VanDerWaalsContact C-N 3.34Å; D110-S112 PolarHBondContact O-N 2.87Å; D110-Y113 PolarHBondContact O-N 2.77Å; D110-E114 WeakPolarHBondContact O-CB 3.45Å; D110-E114 PolarHBondContact O-N 3.5Å; D110-L152 VanDerWaalsContact OD1-CA 3.29Å; D110-L152 WeakPolarHBondContact OD1-CA 3.32Å; D110-T153 PolarHBondContact OD1-N 3.26Å; D110-T153 WeakPolarHBondContact OD2-CB 3.42Å; D110-T153 WeakPolarHBondContact OD2-CG2 3.43Å; D110-T153 PolarHBondContact OD2-OG1 3.43Å; D110-G156 VanDerWaalsContact CG-CA 3.44Å; D110-G156 WeakPolarHBondContact OD1-CA 3.22Å; D110-G156 PolarHBondContact OD2-N 2.93Å
111D98Very high98.5Very high104 Ų10432.8 Ų32.856%0.55616%0.162SC*.Hα-helixtrans-64.1-36.6-177.3-74-10.5000113.2T109 K115T109-D111 VanDerWaalsContact C-N 3.3Å; T109-D111 PolarHBondContact O-N 3.09Å; D111-K115 VanDerWaalsContact O-CD 3.3Å; D111-K115 WeakPolarHBondContact O-CD 3.48Å; D111-K115 VanDerWaalsContact O-CG 3.23Å; D111-K115 WeakPolarHBondContact O-CG 3.15Å; D111-K115 PolarHBondContact O-N 3.31Å
112S98.4Very high98.5Very high22 Ų2235.5 Ų35.515%0.15418%0.179CC..Hα-helixtrans-77.8-38.1178.6-69.80000110.8T109 D110 K115 I116 N228T109-S112 PolarHBondContact O-N 3.24Å; D110-S112 VanDerWaalsContact C-N 3.34Å; D110-S112 PolarHBondContact O-N 2.87Å; S112-K115 PolarHBondContact O-N 3.04Å; S112-I116 PolarHBondContact O-N 3.29Å; S112-N228 PolarHBondContact OG-ND2 2.96Å
113Y98.8Very high98.5Very high3 Ų336.4 Ų36.41%0.01218%0.183CC..Hα-helixtrans-64.5-45176.7-161.2-85.1000111.2V51 F74 L104 I108 T109 D110 K115 I116 F117 L152 C160V51-Y113 WeakPolarHBondContact CB-OH 3.3Å; V51-Y113 WeakPolarHBondContact CG1-OH 3.4Å; F74-Y113 HydrophobicContact CB-CE2 4.08Å; F74-Y113 VanDerWaalsContact CB-OH 3.24Å; F74-Y113 WeakPolarHBondContact CB-OH 3.48Å; L104-Y113 HydrophobicContact CD1-CD2 4.21Å; L104-Y113 HydrophobicContact CD1-CE2 3.81Å; I108-Y113 HydrophobicContact CG1-CD2 3.98Å; I108-Y113 HydrophobicContact CG2-CD2 4Å; T109-Y113 WeakPolarHBondContact O-CB 3.34Å; T109-Y113 PolarHBondContact O-N 2.76Å; D110-Y113 PolarHBondContact O-N 2.77Å; Y113-K115 VanDerWaalsContact C-N 3.3Å; Y113-K115 PolarHBondContact O-N 2.85Å; Y113-I116 WeakPolarHBondContact O-CG1 3.28Å; Y113-I116 PolarHBondContact O-N 3.43Å; Y113-I116 VanDerWaalsContact O-N 3.12Å; Y113-F117 HydrophobicContact CD1-CB 3.96Å; Y113-F117 HydrophobicContact CD1-CD2 4.5Å; Y113-F117 HydrophobicContact CD1-CG 4.44Å; Y113-F117 HydrophobicContact CE1-CB 3.95Å; Y113-F117 AromaticContact CE1-CD2 3.66Å; Y113-F117 HydrophobicContact CE1-CD2 3.66Å; Y113-F117 HydrophobicContact CE1-CE2 4.46Å; Y113-F117 HydrophobicContact CE1-CG 4.01Å; Y113-F117 VanDerWaalsContact O-CB 3.23Å; Y113-F117 WeakPolarHBondContact O-CB 3.37Å; Y113-F117 PolarHBondContact O-N 2.86Å; Y113-L152 HydrophobicContact CD1-CD1 4.38Å; Y113-L152 HydrophobicContact CD2-CD1 3.96Å; Y113-L152 HydrophobicContact CD2-CD2 3.9Å; Y113-L152 HydrophobicContact CD2-CG 4.44Å; Y113-L152 HydrophobicContact CE1-CD1 4.41Å; Y113-L152 HydrophobicContact CE2-CD1 3.98Å; Y113-L152 HydrophobicContact CG-CD1 4.15Å; Y113-L152 HydrophobicContact CG-CD2 3.81Å; Y113-C160 WeakPolarHBondContact CE1-SG 3.44Å
114E98.5Very high98.5Very high59 Ų5936.1 Ų36.128%0.27618%0.181SC..Hα-helixtrans-59.4-40.7177.5-17217517600112.2D110 I116 Q118 K159D110-E114 WeakPolarHBondContact O-CB 3.45Å; D110-E114 PolarHBondContact O-N 3.5Å; E114-I116 PolarHBondContact O-N 2.87Å; E114-Q118 HydrophobicContact CG-CG 4.21Å; E114-Q118 PolarHBondContact O-N 3.22Å; E114-Q118 PolarHBondContact OE1-NE2 3.39Å; E114-K159 WeakPolarHBondContact OE2-CD 3.32Å; E114-K159 IonicContact OE2-NZ 3.95Å; E114-K159 PolarHBondContact OE2-NZ 3.3Å
115K98.4Very high98.4Very high144 Ų14437.3 Ų37.363%0.62619%0.187SC*.Hα-helixtrans-65.9-21.2178.7-74.6169-170.5162.20114D111 S112 Y113 P119D111-K115 VanDerWaalsContact O-CD 3.3Å; D111-K115 WeakPolarHBondContact O-CD 3.48Å; D111-K115 VanDerWaalsContact O-CG 3.23Å; D111-K115 WeakPolarHBondContact O-CG 3.15Å; D111-K115 PolarHBondContact O-N 3.31Å; S112-K115 PolarHBondContact O-N 3.04Å; Y113-K115 VanDerWaalsContact C-N 3.3Å; Y113-K115 PolarHBondContact O-N 2.85Å; K115-P119 WeakPolarHBondContact O-CD 3.42Å; K115-P119 WeakPolarHBondContact O-CG 3.46Å
116I98.7Very high98.4Very high2 Ų239.2 Ų39.21%0.0119%0.194CC..Hα-helixtrans-101.3-40177.162.2172.6000111.8F74 F102 L104 S112 Y113 E114 I120 L235 M239F74-I116 HydrophobicContact CD1-CD1 4.32Å; F102-I116 HydrophobicContact CD1-CD1 4.07Å; F102-I116 HydrophobicContact CD2-CB 4.5Å; F102-I116 HydrophobicContact CE1-CD1 3.72Å; F102-I116 HydrophobicContact CE2-CB 3.7Å; F102-I116 HydrophobicContact CE2-CD1 4.19Å; F102-I116 HydrophobicContact CE2-CG1 4.41Å; F102-I116 HydrophobicContact CE2-CG2 4.11Å; F102-I116 HydrophobicContact CG-CD1 4.47Å; F102-I116 HydrophobicContact CZ-CB 3.73Å; F102-I116 HydrophobicContact CZ-CD1 3.8Å; F102-I116 HydrophobicContact CZ-CG1 4.33Å; F102-I116 HydrophobicContact CZ-CG2 3.69Å; L104-I116 HydrophobicContact CD2-CD1 3.57Å; S112-I116 PolarHBondContact O-N 3.29Å; Y113-I116 WeakPolarHBondContact O-CG1 3.28Å; Y113-I116 PolarHBondContact O-N 3.43Å; Y113-I116 VanDerWaalsContact O-N 3.12Å; E114-I116 PolarHBondContact O-N 2.87Å; I116-I120 WeakPolarHBondContact O-CB 3.36Å; I116-I120 VanDerWaalsContact O-CG1 3.26Å; I116-I120 WeakPolarHBondContact O-CG1 3.38Å; I116-I120 PolarHBondContact O-N 3.25Å; I116-L235 HydrophobicContact CD1-CD2 4.2Å; I116-L235 HydrophobicContact CG2-CB 4.04Å; I116-L235 HydrophobicContact CG2-CD1 4.06Å; I116-L235 HydrophobicContact CG2-CD2 4.17Å; I116-L235 HydrophobicContact CG2-CG 4.32Å; I116-M239 HydrophobicContact CB-SD 4.5Å; I116-M239 HydrophobicContact CG2-CG 4.24Å; I116-M239 HydrophobicContact CG2-SD 3.87Å
117F98.8Very high98.3Very high2 Ų237.9 Ų37.91%0.00919%0.189CC..Hα-helixtrans-64.9-55.3-174.8-176-93.2000110.9V49 V51 F74 Y113 I120 V121 M135 C160 F163 I164V49-F117 HydrophobicContact CG1-CE2 3.91Å; V49-F117 HydrophobicContact CG1-CZ 4.04Å; V51-F117 HydrophobicContact CG1-CD2 4.3Å; V51-F117 HydrophobicContact CG1-CE2 3.58Å; V51-F117 HydrophobicContact CG1-CZ 4.3Å; F74-F117 AromaticContact CD2-CD2 3.83Å; F74-F117 HydrophobicContact CD2-CD2 3.83Å; F74-F117 HydrophobicContact CD2-CE2 4.08Å; F74-F117 HydrophobicContact CE1-CD2 4.34Å; F74-F117 AromaticContact CE2-CD2 3.52Å; F74-F117 HydrophobicContact CE2-CD2 3.52Å; F74-F117 AromaticContact CE2-CE2 3.8Å; F74-F117 HydrophobicContact CE2-CE2 3.8Å; F74-F117 HydrophobicContact CG-CD2 4.37Å; F74-F117 HydrophobicContact CZ-CB 4.5Å; F74-F117 AromaticContact CZ-CD2 3.81Å; F74-F117 HydrophobicContact CZ-CD2 3.81Å; F74-F117 HydrophobicContact CZ-CE2 4.48Å; F74-F117 HydrophobicContact CZ-CG 4.44Å; Y113-F117 HydrophobicContact CD1-CB 3.96Å; Y113-F117 HydrophobicContact CD1-CD2 4.5Å; Y113-F117 HydrophobicContact CD1-CG 4.44Å; Y113-F117 HydrophobicContact CE1-CB 3.95Å; Y113-F117 AromaticContact CE1-CD2 3.66Å; Y113-F117 HydrophobicContact CE1-CD2 3.66Å; Y113-F117 HydrophobicContact CE1-CE2 4.46Å; Y113-F117 HydrophobicContact CE1-CG 4.01Å; Y113-F117 VanDerWaalsContact O-CB 3.23Å; Y113-F117 WeakPolarHBondContact O-CB 3.37Å; Y113-F117 PolarHBondContact O-N 2.86Å; F117-I120 PolarHBondContact O-N 3.27Å; F117-V121 HydrophobicContact CD1-CG2 4.05Å; F117-V121 HydrophobicContact CD2-CG2 4.06Å; F117-V121 HydrophobicContact CE1-CG2 3.88Å; F117-V121 HydrophobicContact CE2-CG2 3.87Å; F117-V121 HydrophobicContact CG-CG2 4.15Å; F117-V121 HydrophobicContact CZ-CG2 3.78Å; F117-V121 WeakPolarHBondContact O-CB 3.4Å; F117-V121 WeakPolarHBondContact O-CG2 3.4Å; F117-V121 PolarHBondContact O-N 3.46Å; F117-M135 HydrophobicContact CZ-CE 4.49Å; F117-C160 HydrophobicContact CD1-CB 4.25Å; F117-C160 HydrophobicContact CE1-CB 3.72Å; F117-C160 HydrophobicContact CE2-CB 4.12Å; F117-C160 HydrophobicContact CZ-CB 3.65Å; F117-F163 HydrophobicContact CD1-CD1 4.22Å; F117-F163 HydrophobicContact CE1-CB 4.4Å; F117-F163 AromaticContact CE1-CD1 3.87Å; F117-F163 HydrophobicContact CE1-CD1 3.87Å; F117-F163 HydrophobicContact CE1-CG 4.48Å; F117-I164 HydrophobicContact CE1-CG1 4.3Å; F117-I164 HydrophobicContact CZ-CD1 4.37Å; F117-I164 HydrophobicContact CZ-CG1 4.1Å
118Q98.6Very high98.3Very high62 Ų6237.9 Ų37.929%0.2919%0.189SC..Hα-helixtrans-61.4-48.1-174.5-59.2-177.77.300112.7E114 I120 T122 F163E114-Q118 HydrophobicContact CG-CG 4.21Å; E114-Q118 PolarHBondContact O-N 3.22Å; E114-Q118 PolarHBondContact OE1-NE2 3.39Å; Q118-I120 PolarHBondContact O-N 3.28Å; Q118-T122 VanDerWaalsContact O-CB 3.22Å; Q118-T122 WeakPolarHBondContact O-CB 3.49Å; Q118-T122 PolarHBondContact O-N 2.9Å; Q118-T122 PolarHBondContact O-OG1 3.27Å; Q118-F163 HydrophobicContact CB-CD2 4.08Å; Q118-F163 HydrophobicContact CB-CE1 4.48Å; Q118-F163 HydrophobicContact CB-CE2 3.8Å; Q118-F163 HydrophobicContact CB-CZ 4.04Å; Q118-F163 HydrophobicContact CG-CD1 4.43Å; Q118-F163 HydrophobicContact CG-CD2 3.58Å; Q118-F163 HydrophobicContact CG-CE2 3.84Å; Q118-F163 HydrophobicContact CG-CG 3.91Å; Q118-F163 HydrophobicContact CG-CZ 4.4Å
119P98.5Very high98.3Very high50 Ų5043.1 Ų43.133%0.32521%0.213SC..Hα-helixtrans-65-41.5-179.2-24.637.6000113.3K115 K123 M239K115-P119 WeakPolarHBondContact O-CD 3.42Å; K115-P119 WeakPolarHBondContact O-CG 3.46Å; P119-K123 WeakPolarHBondContact O-CB 3.36Å; P119-K123 PolarHBondContact O-N 2.85Å; P119-M239 HydrophobicContact CB-CE 3.83Å; P119-M239 HydrophobicContact CG-CE 4.02Å
120I98.7Very high98.2Very high0 Ų041.4 Ų41.40%020%0.203CC..Hα-helixtrans-68.3-47.6-179.2-66.1-60.1000110.8L72 F74 V100 F102 I116 F117 Q118 T122 K123 A124 M239 L242 E243L72-I120 HydrophobicContact CD1-CG2 3.7Å; L72-I120 HydrophobicContact CD2-CG2 4.4Å; F74-I120 HydrophobicContact CE1-CB 4.41Å; F74-I120 HydrophobicContact CE1-CG2 4.46Å; F74-I120 HydrophobicContact CZ-CB 4.11Å; F74-I120 HydrophobicContact CZ-CG2 3.97Å; V100-I120 HydrophobicContact CG1-CG2 4.44Å; F102-I120 HydrophobicContact CD2-CG1 4.17Å; F102-I120 HydrophobicContact CE2-CG1 4.07Å; I116-I120 WeakPolarHBondContact O-CB 3.36Å; I116-I120 VanDerWaalsContact O-CG1 3.26Å; I116-I120 WeakPolarHBondContact O-CG1 3.38Å; I116-I120 PolarHBondContact O-N 3.25Å; F117-I120 PolarHBondContact O-N 3.27Å; Q118-I120 PolarHBondContact O-N 3.28Å; I120-T122 PolarHBondContact O-N 3.36Å; I120-K123 PolarHBondContact O-N 3.37Å; I120-A124 WeakPolarHBondContact O-CB 3.32Å; I120-A124 PolarHBondContact O-N 2.61Å; I120-M239 HydrophobicContact CD1-CG 4.46Å; I120-L242 HydrophobicContact CD1-CB 3.91Å; I120-L242 HydrophobicContact CD1-CD1 4.26Å; I120-L242 HydrophobicContact CG2-CD1 4.47Å; I120-E243 HydrophobicContact CD1-CG 4.42Å
121V98.8Very high98.2Very high0 Ų043.3 Ų43.30%021%0.211CC..Hα-helixtrans-62-43.7176.4176.30000110.7L72 F74 F117 K123 A124 I125 F163 I164L72-V121 HydrophobicContact CD2-CB 4.31Å; L72-V121 HydrophobicContact CD2-CG2 3.61Å; F74-V121 HydrophobicContact CE2-CG2 4.12Å; F74-V121 HydrophobicContact CZ-CG2 4.17Å; F117-V121 HydrophobicContact CD1-CG2 4.05Å; F117-V121 HydrophobicContact CD2-CG2 4.06Å; F117-V121 HydrophobicContact CE1-CG2 3.88Å; F117-V121 HydrophobicContact CE2-CG2 3.87Å; F117-V121 HydrophobicContact CG-CG2 4.15Å; F117-V121 HydrophobicContact CZ-CG2 3.78Å; F117-V121 WeakPolarHBondContact O-CB 3.4Å; F117-V121 WeakPolarHBondContact O-CG2 3.4Å; F117-V121 PolarHBondContact O-N 3.46Å; V121-K123 VanDerWaalsContact C-N 3.3Å; V121-K123 PolarHBondContact O-N 2.97Å; V121-A124 PolarHBondContact O-N 3.49Å; V121-I125 HydrophobicContact CG1-CD1 3.82Å; V121-I125 HydrophobicContact CG1-CG1 4.36Å; V121-I125 WeakPolarHBondContact O-CG1 3.32Å; V121-I125 PolarHBondContact O-N 2.87Å; V121-F163 HydrophobicContact CB-CD1 4.46Å; V121-F163 HydrophobicContact CB-CE1 3.85Å; V121-F163 HydrophobicContact CG1-CD1 4.2Å; V121-F163 HydrophobicContact CG1-CE1 3.66Å; V121-I164 HydrophobicContact CG1-CD1 3.58Å
122T98.6Very high98.2Very high60 Ų6038.5 Ų38.537%0.36819%0.185SC..Hα-helixtrans-55.7-46.9175.9-60.40000111.2Q118 I120 R126 F163Q118-T122 VanDerWaalsContact O-CB 3.22Å; Q118-T122 WeakPolarHBondContact O-CB 3.49Å; Q118-T122 PolarHBondContact O-N 2.9Å; Q118-T122 PolarHBondContact O-OG1 3.27Å; I120-T122 PolarHBondContact O-N 3.36Å; T122-R126 WeakPolarHBondContact O-CB 3.41Å; T122-R126 PolarHBondContact O-N 3.16Å; T122-F163 VanDerWaalsContact OG1-CZ 3.32Å; T122-F163 WeakPolarHBondContact OG1-CZ 3.38Å
123K98Very high98.2Very high18 Ų1837.6 Ų37.68%0.07818%0.179CC..Hα-helixtrans-69-41.8-179-173.1175.6174.9101.10111.5P119 I120 V121 R126 C127 E243 L246 D247P119-K123 WeakPolarHBondContact O-CB 3.36Å; P119-K123 PolarHBondContact O-N 2.85Å; I120-K123 PolarHBondContact O-N 3.37Å; V121-K123 VanDerWaalsContact C-N 3.3Å; V121-K123 PolarHBondContact O-N 2.97Å; K123-R126 PolarHBondContact O-N 3.07Å; K123-C127 WeakPolarHBondContact O-CB 3.49Å; K123-C127 PolarHBondContact O-N 2.89Å; K123-C127 PolarHBondContact O-SG 3.35Å; K123-C127 VanDerWaalsContact O-SG 3.37Å; K123-E243 HydrophobicContact CD-CB 4.15Å; K123-E243 HydrophobicContact CD-CG 3.81Å; K123-E243 WeakPolarHBondContact CE-O 3.47Å; K123-L246 HydrophobicContact CB-CD1 4.02Å; K123-L246 HydrophobicContact CD-CB 4.02Å; K123-L246 HydrophobicContact CD-CD1 3.86Å; K123-L246 HydrophobicContact CG-CB 4.14Å; K123-L246 HydrophobicContact CG-CD1 3.82Å; K123-D247 WeakPolarHBondContact CE-OD1 3.38Å; K123-D247 IonicContact NZ-OD1 2.86Å; K123-D247 PolarHBondContact NZ-OD1 3.4Å; K123-D247 IonicContact NZ-OD2 2.64Å; K123-D247 PolarHBondContact NZ-OD2 2.84Å
124A98.4Very high98.2Very high0 Ų037.4 Ų37.40%018%0.178CC..Hα-helixtrans-56.6-51.2174.800000110.9M70 L72 I120 V121 R126 C127 Y128 L246M70-A124 HydrophobicContact SD-CB 3.88Å; L72-A124 HydrophobicContact CD2-CB 4.23Å; I120-A124 WeakPolarHBondContact O-CB 3.32Å; I120-A124 PolarHBondContact O-N 2.61Å; V121-A124 PolarHBondContact O-N 3.49Å; A124-R126 VanDerWaalsContact C-N 3.34Å; A124-R126 PolarHBondContact O-N 3.43Å; A124-C127 PolarHBondContact O-N 3.22Å; A124-Y128 WeakPolarHBondContact O-CB 3.24Å; A124-Y128 PolarHBondContact O-N 3.44Å; A124-L246 HydrophobicContact CB-CD2 4.33Å
125I98.4Very high98.2Very high26 Ų2634.6 Ų34.613%0.13317%0.165CC..Hα-helixtrans-59.5-44.4176.7-68.6173.2000111.3L47 V121 Q129 P130 I133 Q167L47-I125 HydrophobicContact CD2-CD1 4.42Å; L47-I125 HydrophobicContact CD2-CG1 3.69Å; V121-I125 HydrophobicContact CG1-CD1 3.82Å; V121-I125 HydrophobicContact CG1-CG1 4.36Å; V121-I125 WeakPolarHBondContact O-CG1 3.32Å; V121-I125 PolarHBondContact O-N 2.87Å; I125-Q129 VanDerWaalsContact O-CA 3.27Å; I125-Q129 WeakPolarHBondContact O-CA 3.12Å; I125-Q129 PolarHBondContact O-N 3.46Å; I125-P130 HydrophobicContact CG1-CG 4.3Å; I125-I133 HydrophobicContact CD1-CD1 4.09Å; I125-Q167 HydrophobicContact CD1-CB 4.21Å; I125-Q167 HydrophobicContact CD1-CG 3.6Å
126R97Very high98.2Very high150 Ų15027.8 Ų27.857%0.56614%0.135SC*.Hα-helixtrans-63-45.3180-175.2-177.768.7-146.24.1112.7T122 K123 A124T122-R126 WeakPolarHBondContact O-CB 3.41Å; T122-R126 PolarHBondContact O-N 3.16Å; K123-R126 PolarHBondContact O-N 3.07Å; A124-R126 VanDerWaalsContact C-N 3.34Å; A124-R126 PolarHBondContact O-N 3.43Å
127C96.6Very high98.2Very high20 Ų2027.7 Ų27.714%0.13514%0.135CC..Hα-helixtrans-77-39.1-177.2-65.20000112K123 A124 M249 A252K123-C127 WeakPolarHBondContact O-CB 3.49Å; K123-C127 PolarHBondContact O-N 2.89Å; K123-C127 PolarHBondContact O-SG 3.35Å; K123-C127 VanDerWaalsContact O-SG 3.37Å; A124-C127 PolarHBondContact O-N 3.22Å; C127-M249 HydrophobicContact CB-CE 3.64Å; C127-A252 PolarHBondContact O-N 2.59Å
128Y98Very high98.2Very high0 Ų027.6 Ų27.60%013%0.134CC..Hα-helixtrans-89.2-30.6-173.3-171.4-126.2000113.7R45 V46 L47 D67 R68 V69 M70 Y98 A124 P130 M249 P253R45-Y128 HydrophobicContact CB-CE1 3.79Å; R45-Y128 HydrophobicContact CB-CE2 4.36Å; R45-Y128 VanDerWaalsContact CD-O 3.25Å; R45-Y128 WeakPolarHBondContact CD-O 3.48Å; R45-Y128 HydrophobicContact CG-CE1 4.43Å; R45-Y128 HydrophobicContact CG-CE2 4.1Å; R45-Y128 PolarHBondContact NE-O 3.04Å; V46-Y128 WeakPolarHBondContact O-CE1 3.49Å; L47-Y128 HydrophobicContact CB-CD1 4.43Å; D67-Y128 VanDerWaalsContact O-CE2 3.32Å; D67-Y128 WeakPolarHBondContact O-CE2 3.42Å; D67-Y128 PolarHBondContact O-OH 2.91Å; R68-Y128 WeakPolarHBondContact CA-OH 3.37Å; R68-Y128 PolarHBondContact O-OH 3.22Å; V69-Y128 WeakPolarHBondContact CA-OH 3.27Å; V69-Y128 PolarHBondContact N-OH 3.31Å; V69-Y128 VanDerWaalsContact N-OH 3.13Å; M70-Y128 HydrophobicContact CB-CD1 3.63Å; M70-Y128 HydrophobicContact CB-CD2 4.29Å; M70-Y128 HydrophobicContact CB-CE1 3.59Å; M70-Y128 HydrophobicContact CB-CE2 4.27Å; M70-Y128 HydrophobicContact CB-CG 4Å; M70-Y128 HydrophobicContact CE-CD1 4.47Å; M70-Y128 HydrophobicContact CE-CD2 3.93Å; M70-Y128 HydrophobicContact CE-CG 3.75Å; M70-Y128 HydrophobicContact SD-CD1 4.19Å; M70-Y128 HydrophobicContact SD-CG 4Å; Y98-Y128 AromaticContact CD1-CD2 3.76Å; Y98-Y128 HydrophobicContact CD1-CD2 3.76Å; Y98-Y128 AromaticContact CD1-CE2 3.5Å; Y98-Y128 HydrophobicContact CD1-CE2 3.5Å; Y98-Y128 AromaticContact CE1-CD2 3.56Å; Y98-Y128 HydrophobicContact CE1-CD2 3.56Å; Y98-Y128 AromaticContact CE1-CE2 3.39Å; Y98-Y128 HydrophobicContact CE1-CE2 3.39Å; A124-Y128 WeakPolarHBondContact O-CB 3.24Å; A124-Y128 PolarHBondContact O-N 3.44Å; Y128-P130 HydrophobicContact CD1-CB 3.94Å; Y128-P130 HydrophobicContact CD1-CG 4.34Å; Y128-P130 HydrophobicContact CE1-CB 4.2Å; Y128-M249 HydrophobicContact CD2-CE 4.24Å; Y128-M249 HydrophobicContact CD2-SD 4.37Å; Y128-P253 HydrophobicContact CE2-CG 4.42Å
129Q97.4Very high98.2Very high110 Ų11024.7 Ų24.751%0.51412%0.121SC..  trans51.158.6-176-57.3-176.3-15.600112.6R45 I125 A252R45-Q129 VanDerWaalsContact CZ-O 3.24Å; R45-Q129 PolarHBondContact NE-O 3.1Å; R45-Q129 PolarHBondContact NH2-O 3.18Å; I125-Q129 VanDerWaalsContact O-CA 3.27Å; I125-Q129 WeakPolarHBondContact O-CA 3.12Å; I125-Q129 PolarHBondContact O-N 3.46Å; Q129-A252 HydrophobicContact CB-CB 4.21Å; Q129-A252 HydrophobicContact CG-CB 4.31Å
130P98Very high98.2Very high7 Ų722.3 Ų22.35%0.04511%0.106CC..  trans-63.6152.1176.929.8-35.1000111.3L47 I125 Y128 L169L47-P130 HydrophobicContact CB-CB 3.53Å; L47-P130 HydrophobicContact CB-CG 3.7Å; L47-P130 HydrophobicContact CD2-CG 4.02Å; I125-P130 HydrophobicContact CG1-CG 4.3Å; Y128-P130 HydrophobicContact CD1-CB 3.94Å; Y128-P130 HydrophobicContact CD1-CG 4.34Å; Y128-P130 HydrophobicContact CE1-CB 4.2Å; P130-L169 HydrophobicContact CG-CD1 3.98Å
131E96.9Very high98.2Very high70 Ų7022.3 Ų22.333%0.32711%0.106SC..SBendtrans-100.1-13.5175.5-64.8171.6115.100112.5F43 Q44 R45 P170F43-E131 HydrophobicContact CB-CB 4.3Å; F43-E131 HydrophobicContact CD1-CB 3.63Å; F43-E131 HydrophobicContact CE1-CB 4.41Å; F43-E131 HydrophobicContact CG-CB 4.35Å; Q44-E131 WeakPolarHBondContact CA-OE2 3.25Å; Q44-E131 WeakPolarHBondContact CB-OE2 3.1Å; Q44-E131 PolarHBondContact N-OE2 2.92Å; R45-E131 PolarHBondContact O-N 2.97Å; E131-P170 VanDerWaalsContact O-CD 3.31Å; E131-P170 WeakPolarHBondContact O-CD 3.5Å
132V98.2Very high98.2Very high4 Ų422.4 Ų22.42%0.02411%0.106CC..EExtended strand (participates in β ladder)trans-150.8145.8176.556.80000108.8L39 F43 V46 L47 P170L39-V132 HydrophobicContact CD1-CG1 4.36Å; L39-V132 HydrophobicContact CD1-CG2 4.11Å; L39-V132 HydrophobicContact CD2-CG2 4.21Å; F43-V132 HydrophobicContact CB-CG1 3.88Å; F43-V132 HydrophobicContact CD1-CB 4.41Å; F43-V132 HydrophobicContact CD1-CG1 4.34Å; F43-V132 HydrophobicContact CD2-CB 4.06Å; F43-V132 HydrophobicContact CD2-CG1 3.63Å; F43-V132 HydrophobicContact CE1-CB 4.49Å; F43-V132 HydrophobicContact CE2-CB 4.16Å; F43-V132 HydrophobicContact CE2-CG1 4.21Å; F43-V132 HydrophobicContact CE2-CG2 4.46Å; F43-V132 HydrophobicContact CG-CB 4.18Å; F43-V132 HydrophobicContact CG-CG1 3.69Å; F43-V132 HydrophobicContact CZ-CB 4.36Å; V46-V132 HydrophobicContact CB-CG1 4.2Å; V46-V132 HydrophobicContact CG1-CG1 4.12Å; V46-V132 HydrophobicContact CG2-CG1 3.69Å; L47-V132 PolarHBondContact N-O 2.86Å; V132-P170 WeakPolarHBondContact CA-O 3.32Å; V132-P170 HydrophobicContact CB-CB 4.25Å; V132-P170 HydrophobicContact CG2-CB 4.06Å; V132-P170 WeakPolarHBondContact CG2-O 3.41Å
133I98.8Very high98.1Very high2 Ų219.8 Ų19.81%0.019%0.09CC..EExtended strand (participates in β ladder)trans-111.9132.8174.2-60.7178000109.1L47 V49 I125 M135 I164 L169 P170 L171 L172L47-I133 HydrophobicContact CB-CG1 4.33Å; L47-I133 HydrophobicContact CD2-CD1 4.38Å; L47-I133 HydrophobicContact CD2-CG1 4.34Å; L47-I133 CarbonylContact O-C 3.4Å; L47-I133 VanDerWaalsContact O-CA 3.29Å; L47-I133 WeakPolarHBondContact O-CA 3.16Å; V49-I133 HydrophobicContact CG2-CG2 4.1Å; I125-I133 HydrophobicContact CD1-CD1 4.09Å; I133-M135 HydrophobicContact CG2-CB 4.49Å; I133-I164 HydrophobicContact CD1-CD1 4.28Å; I133-I164 HydrophobicContact CD1-CG2 4.04Å; I133-I164 HydrophobicContact CG2-CG2 3.97Å; I133-L169 HydrophobicContact CD1-CB 4.42Å; I133-L169 HydrophobicContact CD1-CD1 3.94Å; I133-L169 HydrophobicContact CG1-CB 4.41Å; I133-L169 HydrophobicContact CG1-CD1 4.08Å; I133-P170 PolarHBondContact N-O 2.92Å; I133-L171 HydrophobicContact CB-CD1 3.94Å; I133-L171 HydrophobicContact CG2-CD1 3.84Å; I133-L171 WeakPolarHBondContact O-CA 3.32Å; I133-L172 PolarHBondContact O-N 3.48Å
134V98.9Very high98Very high0 Ų021.5 Ų21.50%011%0.112CC..EExtended strand (participates in β ladder)trans-108.7118.2166-179.40000106.5I32 I36 L39 V46 L47 Y48 V49 L172 L174I32-V134 HydrophobicContact CG2-CG1 4.16Å; I36-V134 HydrophobicContact CG1-CB 4.48Å; I36-V134 HydrophobicContact CG1-CG2 4Å; L39-V134 HydrophobicContact CD1-CG2 3.49Å; L39-V134 VanDerWaalsContact CD1-CG2 3.49Å; V46-V134 HydrophobicContact CG1-CG2 3.86Å; L47-V134 PolarHBondContact O-N 3.19Å; Y48-V134 CarbonylContact C-O 3.54Å; Y48-V134 VanDerWaalsContact CA-O 3.29Å; Y48-V134 WeakPolarHBondContact CA-O 3.46Å; Y48-V134 HydrophobicContact CD2-CB 4.22Å; Y48-V134 HydrophobicContact CD2-CG1 4.05Å; Y48-V134 HydrophobicContact CE2-CG1 4.48Å; V49-V134 PolarHBondContact N-O 3.41Å; V134-L172 CarbonylContact C-O 3.44Å; V134-L172 WeakPolarHBondContact CA-O 3.4Å; V134-L172 HydrophobicContact CG1-CD2 4.18Å; V134-L172 HydrophobicContact CG1-CG 4.42Å; V134-L172 HydrophobicContact CG2-CB 4.32Å; V134-L172 HydrophobicContact CG2-CD2 4.31Å; V134-L174 HydrophobicContact CG1-CD1 3.62Å; V134-L174 HydrophobicContact CG1-CG 4.36Å
135M98.8Very high98Very high0 Ų022.2 Ų22.20%012%0.116CC..EExtended strand (participates in β ladder)trans-115.1118.1-177.5-173176.4176.100109.8V49 V51 F117 I133 C160 V161 I164 L171 L172 L173 L174V49-M135 HydrophobicContact CB-CG 4.41Å; V49-M135 CarbonylContact O-C 3.58Å; V49-M135 VanDerWaalsContact O-CA 3.26Å; V49-M135 WeakPolarHBondContact O-CA 3.35Å; V51-M135 HydrophobicContact CG1-CE 4.05Å; V51-M135 HydrophobicContact CG2-CE 4.07Å; F117-M135 HydrophobicContact CZ-CE 4.49Å; I133-M135 HydrophobicContact CG2-CB 4.49Å; M135-C160 HydrophobicContact CE-CB 3.77Å; M135-V161 HydrophobicContact CE-CG2 3.77Å; M135-V161 HydrophobicContact SD-CG2 4Å; M135-I164 HydrophobicContact CE-CG1 4.48Å; M135-I164 HydrophobicContact SD-CB 4.05Å; M135-I164 HydrophobicContact SD-CG1 3.77Å; M135-I164 HydrophobicContact SD-CG2 4.22Å; M135-L171 HydrophobicContact CB-CD1 4.12Å; M135-L172 PolarHBondContact N-O 3.47Å; M135-L173 HydrophobicContact CB-CD2 3.88Å; M135-L173 HydrophobicContact CG-CD2 4.36Å; M135-L173 WeakPolarHBondContact O-CA 3.46Å; M135-L173 HydrophobicContact SD-CD2 4.14Å; M135-L174 PolarHBondContact O-N 2.92Å
136Q98.8Very high97.9Very high0 Ų026.4 Ų26.40%013%0.13CC..EExtended strand (participates in β ladder)trans-82.8130.6169.7-168.3-78.14.700107.8I32 Y48 V49 D50 V51 D52 G175I32-Q136 HydrophobicContact CD1-CG 4.36Å; Y48-Q136 HydrophobicContact CE2-CB 3.84Å; Y48-Q136 VanDerWaalsContact OH-CB 3.29Å; Y48-Q136 WeakPolarHBondContact OH-CB 3.05Å; V49-Q136 PolarHBondContact O-N 2.86Å; D50-Q136 HydrophobicContact CB-CB 4.36Å; D50-Q136 PolarHBondContact OD1-OE1 3.43Å; V51-Q136 VanDerWaalsContact CG2-O 3.32Å; V51-Q136 WeakPolarHBondContact CG2-O 3.46Å; V51-Q136 PolarHBondContact N-O 3.03Å; D52-Q136 PolarHBondContact OD2-NE2 2.85Å; Q136-G175 WeakPolarHBondContact CG-O 3.3Å; Q136-G175 PolarHBondContact NE2-O 3.3Å
137C98.7Very high97.8Very high0 Ų022 Ų220%012%0.118CC..  trans-122.349.6-174.6-56.40000111.2W11 A139 L174 G175 W188 E191W11-C137 HydrophobicContact CZ3-CB 4.03Å; C137-A139 PolarHBondContact O-N 2.81Å; C137-L174 VanDerWaalsContact CB-O 3.22Å; C137-L174 WeakPolarHBondContact CB-O 3.47Å; C137-L174 PolarHBondContact N-O 3.4Å; C137-G175 PolarHBondContact N-O 2.84Å; C137-W188 PolarHBondContact O-NE1 2.73Å; C137-E191 WeakPolarHBondContact CB-OE2 3.23Å
138G98.5Very high97.7Very high0 Ų021.5 Ų21.50%012%0.116CC..  trans-54.3121.717200000111.5D52 D140 S141 H157 G177D52-G138 WeakPolarHBondContact OD2-CA 3.47Å; G138-D140 VanDerWaalsContact C-N 3.3Å; G138-D140 PolarHBondContact O-N 2.97Å; G138-S141 PolarHBondContact O-OG 3.49Å; G138-H157 PolarHBondContact O-NE2 3.43Å; G138-G177 CarbonylContact C-O 3.59Å; G138-G177 WeakPolarHBondContact CA-O 3.09Å
139A98.5Very high97.6Very high2 Ų223.1 Ų23.12%0.01713%0.127CC..G310 helixtrans-86.62-17600000113.1C137 S141 L142 G177 V184 C187C137-A139 PolarHBondContact O-N 2.81Å; A139-S141 PolarHBondContact O-N 2.86Å; A139-L142 HydrophobicContact CB-CD1 4Å; A139-L142 HydrophobicContact CB-CG 4.49Å; A139-L142 WeakPolarHBondContact O-CB 3.32Å; A139-L142 WeakPolarHBondContact O-CD1 3.14Å; A139-L142 WeakPolarHBondContact O-CG 3.22Å; A139-L142 PolarHBondContact O-N 2.82Å; A139-G177 PolarHBondContact N-O 2.99Å; A139-V184 HydrophobicContact CB-CB 4.44Å; A139-V184 HydrophobicContact CB-CG2 4.1Å; A139-C187 HydrophobicContact CB-CB 4.11Å
140D98.3Very high97.6Very high0 Ų017.9 Ų17.90%010%0.103CC..G310 helixtrans-74.7-9.9174.259.311.7000113.5D52 C53 H54 G138 L142 D145 G148 G177 Y179D52-D140 VanDerWaalsContact CG-OD1 3.26Å; D52-D140 VanDerWaalsContact OD1-OD1 3.1Å; D52-D140 VanDerWaalsContact OD1-OD2 3.1Å; C53-D140 PolarHBondContact N-OD1 3Å; C53-D140 PolarHBondContact SG-OD1 2.83Å; C53-D140 VanDerWaalsContact SG-OD1 3.39Å; C53-D140 PolarHBondContact SG-OD2 3.19Å; H54-D140 IonicContact CE1-OD2 3.61Å; H54-D140 PolarHBondContact CE1-OD2 2.95Å; H54-D140 IonicContact ND1-OD2 2.71Å; H54-D140 PolarHBondContact ND1-OD2 3.41Å; G138-D140 VanDerWaalsContact C-N 3.3Å; G138-D140 PolarHBondContact O-N 2.97Å; D140-L142 PolarHBondContact O-N 3.01Å; D140-D145 VanDerWaalsContact CA-CG 3.49Å; D140-D145 HydrophobicContact CB-CB 4.45Å; D140-G148 VanDerWaalsContact O-CA 3.3Å; D140-G148 WeakPolarHBondContact O-CA 3.23Å; D140-G177 PolarHBondContact N-O 3.06Å; D140-Y179 HydrophobicContact CB-CD2 3.96Å; D140-Y179 HydrophobicContact CB-CE2 4.05Å
141S98.3Very high97.6Very high0 Ų017.8 Ų17.80%010%0.102CC..G310 helixtrans-71.5-9.1166.365.60000113.4V51 G138 A139 L150 L152 H157V51-S141 VanDerWaalsContact O-CB 3.3Å; V51-S141 WeakPolarHBondContact O-CB 3.4Å; V51-S141 PolarHBondContact O-OG 3.37Å; G138-S141 PolarHBondContact O-OG 3.49Å; A139-S141 PolarHBondContact O-N 2.86Å; S141-L150 VanDerWaalsContact O-CB 3.26Å; S141-L150 WeakPolarHBondContact O-CB 3.17Å; S141-L152 WeakPolarHBondContact O-CB 3.32Å; S141-L152 PolarHBondContact O-N 2.94Å; S141-H157 PolarHBondContact OG-CD2 3.02Å; S141-H157 PolarHBondContact OG-NE2 3.1Å; S141-H157 VanDerWaalsContact OG-NE2 3.14Å
142L98.4Very high97.7Very high1 Ų114.5 Ų14.51%0.0059%0.086CC..BIsolated β-bridgetrans-72.7149.8179.2-64.5178.1000112.9A139 D140 G144 D145 L152 T153 V154 H157 N183 C187 I221A139-L142 HydrophobicContact CB-CD1 4Å; A139-L142 HydrophobicContact CB-CG 4.49Å; A139-L142 WeakPolarHBondContact O-CB 3.32Å; A139-L142 WeakPolarHBondContact O-CD1 3.14Å; A139-L142 WeakPolarHBondContact O-CG 3.22Å; A139-L142 PolarHBondContact O-N 2.82Å; D140-L142 PolarHBondContact O-N 3.01Å; L142-G144 PolarHBondContact O-N 3.41Å; L142-D145 WeakPolarHBondContact O-CB 3.31Å; L142-D145 PolarHBondContact O-N 3.36Å; L142-L152 CarbonylContact C-O 3.57Å; L142-L152 WeakPolarHBondContact CA-O 3.26Å; L142-L152 HydrophobicContact CD2-CB 4.44Å; L142-T153 VanDerWaalsContact CD2-C 3.47Å; L142-V154 HydrophobicContact CD1-CG2 4.28Å; L142-H157 HydrophobicContact CD2-CB 3.89Å; L142-N183 HydrophobicContact CD1-CB 4.26Å; L142-C187 HydrophobicContact CD1-CB 3.78Å; L142-I221 HydrophobicContact CB-CD1 4.23Å; L142-I221 HydrophobicContact CD1-CD1 4.44Å
143T97.9Very high97.7Very high6 Ų614.6 Ų14.64%0.0379%0.087CC..THydrogen-bonded Turntrans-59.6133.2170.6-164.20000111D145 N151 L152 I221 T222 S224T143-D145 VanDerWaalsContact C-N 3.28Å; T143-D145 PolarHBondContact O-N 3.32Å; T143-N151 WeakPolarHBondContact CB-OD1 3.42Å; T143-N151 PolarHBondContact OG1-OD1 3.13Å; T143-L152 WeakPolarHBondContact CB-O 3.38Å; T143-L152 PolarHBondContact N-O 2.98Å; T143-I221 HydrophobicContact CG2-CD1 3.57Å; T143-I221 HydrophobicContact CG2-CG1 3.87Å; T143-T222 WeakPolarHBondContact CG2-O 3.38Å; T143-S224 WeakPolarHBondContact OG1-CB 3.48Å; T143-S224 PolarHBondContact OG1-N 3.39Å; T143-S224 VanDerWaalsContact OG1-N 3.16Å; T143-S224 PolarHBondContact OG1-OG 3.09Å; T143-S224 VanDerWaalsContact OG1-OG 3.09Å
144G95.4Very high97.6Very high53 Ų5314.5 Ų14.555%0.5469%0.087SC..THydrogen-bonded Turntrans75.113-17900000114.5L142 T180L142-G144 PolarHBondContact O-N 3.41Å; G144-T180 PolarHBondContact O-OG1 3.3Å
145D97.5Very high97.6Very high16 Ų1619.4 Ų19.49%0.08611%0.108CC..  trans-62.6153.7162.6-169.773.3000110.9D140 L142 T143 L147 G148 Y179 T180D140-D145 VanDerWaalsContact CA-CG 3.49Å; D140-D145 HydrophobicContact CB-CB 4.45Å; L142-D145 WeakPolarHBondContact O-CB 3.31Å; L142-D145 PolarHBondContact O-N 3.36Å; T143-D145 VanDerWaalsContact C-N 3.28Å; T143-D145 PolarHBondContact O-N 3.32Å; D145-L147 PolarHBondContact OD2-N 2.85Å; D145-G148 PolarHBondContact OD2-N 3.21Å; D145-Y179 PolarHBondContact OD1-N 2.8Å; D145-T180 PolarHBondContact OD1-N 3.12Å
146R95.9Very high97.6Very high113 Ų11319.7 Ų19.743%0.42611%0.111SC..SBendtrans-83.6-30.3-174-149.6-170.272.9-147.4-27.8113.1G285R146-G285 PolarHBondContact NH1-O 3.35Å; R146-G285 PolarHBondContact NH2-O 3.11Å
147L95.4Very high97.6Very high57 Ų5719.7 Ų19.730%0.29811%0.111SC..SBendtrans-108.8-30.9179.1-60-169.7000111.9F26 Y80 D145 Y179F26-L147 HydrophobicContact CE2-CD1 4.35Å; Y80-L147 PolarHBondContact OH-O 3.35Å; D145-L147 PolarHBondContact OD2-N 2.85Å; L147-Y179 HydrophobicContact CB-CD2 3.65Å; L147-Y179 HydrophobicContact CB-CE2 3.99Å; L147-Y179 HydrophobicContact CB-CG 4.14Å; L147-Y179 HydrophobicContact CD1-CD1 3.64Å; L147-Y179 HydrophobicContact CD1-CD2 3.75Å; L147-Y179 HydrophobicContact CD1-CE1 3.61Å; L147-Y179 HydrophobicContact CD1-CE2 3.74Å; L147-Y179 HydrophobicContact CD1-CG 3.7Å; L147-Y179 HydrophobicContact CG-CD1 4.15Å; L147-Y179 HydrophobicContact CG-CD2 3.75Å; L147-Y179 HydrophobicContact CG-CE2 4.19Å; L147-Y179 HydrophobicContact CG-CG 3.72Å
148G95.1Very high97.6Very high10 Ų1019.7 Ų19.710%0.10311%0.111CC..  trans-74.4145.4173.600000113.9Y80 D140 D145Y80-G148 WeakPolarHBondContact OH-CA 3.44Å; D140-G148 VanDerWaalsContact O-CA 3.3Å; D140-G148 WeakPolarHBondContact O-CA 3.23Å; D145-G148 PolarHBondContact OD2-N 3.21Å
149C94.9Very high97.6Very high34 Ų3423.1 Ų23.123%0.2313%0.126CC..  trans-128.124176.957.50000113.4K76 D106 G107K76-C149 WeakPolarHBondContact CD-SG 3.2Å; K76-C149 WeakPolarHBondContact CE-SG 3.38Å; D106-C149 WeakPolarHBondContact CA-O 3.38Å; D106-C149 PolarHBondContact OD1-SG 2.7Å; G107-C149 PolarHBondContact N-O 2.88Å
150L98Very high97.6Very high1 Ų123.2 Ų23.21%0.00513%0.126CC..  trans-80.4172.4164.1-57.1-169.9000109.7C53 K76 L104 I108 S141C53-L150 HydrophobicContact CB-CD1 3.98Å; C53-L150 HydrophobicContact CB-CG 4.11Å; K76-L150 HydrophobicContact CB-CD2 4.39Å; L104-L150 HydrophobicContact CB-CD2 4.42Å; L104-L150 HydrophobicContact CD1-CD1 4.22Å; I108-L150 HydrophobicContact CG2-CB 3.88Å; I108-L150 HydrophobicContact CG2-CD1 4.06Å; I108-L150 HydrophobicContact CG2-CD2 3.76Å; I108-L150 HydrophobicContact CG2-CG 4.08Å; S141-L150 VanDerWaalsContact O-CB 3.26Å; S141-L150 WeakPolarHBondContact O-CB 3.17Å
151N98.1Very high97.6Very high5 Ų523.2 Ų23.23%0.02713%0.126CC..BIsolated β-bridgetrans-132.842.1-174.9-165.622.8000111.4I108 T143 S224 L226I108-N151 CarbonylContact O-C 3.52Å; I108-N151 VanDerWaalsContact O-CA 3.26Å; I108-N151 WeakPolarHBondContact O-CA 3.26Å; I108-N151 WeakPolarHBondContact O-CB 3.32Å; I108-N151 PolarHBondContact O-N 3.47Å; T143-N151 WeakPolarHBondContact CB-OD1 3.42Å; T143-N151 PolarHBondContact OG1-OD1 3.13Å; N151-S224 PolarHBondContact ND2-O 3.41Å; N151-S224 VanDerWaalsContact ND2-O 3.13Å; N151-S224 PolarHBondContact OD1-N 3.12Å; N151-S224 PolarHBondContact OD1-OG 2.89Å; N151-L226 HydrophobicContact CB-CD1 4.48Å
152L98.6Very high97.6Very high0 Ų026.8 Ų26.80%014%0.143CC..BIsolated β-bridgetrans-80.1146.6175.5-57.6-173.2000111.2I108 D110 Y113 S141 L142 T143I108-L152 HydrophobicContact CG2-CD2 4.18Å; D110-L152 VanDerWaalsContact OD1-CA 3.29Å; D110-L152 WeakPolarHBondContact OD1-CA 3.32Å; Y113-L152 HydrophobicContact CD1-CD1 4.38Å; Y113-L152 HydrophobicContact CD2-CD1 3.96Å; Y113-L152 HydrophobicContact CD2-CD2 3.9Å; Y113-L152 HydrophobicContact CD2-CG 4.44Å; Y113-L152 HydrophobicContact CE1-CD1 4.41Å; Y113-L152 HydrophobicContact CE2-CD1 3.98Å; Y113-L152 HydrophobicContact CG-CD1 4.15Å; Y113-L152 HydrophobicContact CG-CD2 3.81Å; S141-L152 WeakPolarHBondContact O-CB 3.32Å; S141-L152 PolarHBondContact O-N 2.94Å; L142-L152 CarbonylContact C-O 3.57Å; L142-L152 WeakPolarHBondContact CA-O 3.26Å; L142-L152 HydrophobicContact CD2-CB 4.44Å; T143-L152 WeakPolarHBondContact CB-O 3.38Å; T143-L152 PolarHBondContact N-O 2.98Å
153T98.3Very high97.6Very high7 Ų727.9 Ų27.94%0.04315%0.148CC..  trans-92.9166.2167.274.40000110.7D110 L142 K155 G156 H157 P223D110-T153 PolarHBondContact OD1-N 3.26Å; D110-T153 WeakPolarHBondContact OD2-CB 3.42Å; D110-T153 WeakPolarHBondContact OD2-CG2 3.43Å; D110-T153 PolarHBondContact OD2-OG1 3.43Å; L142-T153 VanDerWaalsContact CD2-C 3.47Å; T153-K155 PolarHBondContact O-N 2.79Å; T153-K155 VanDerWaalsContact O-N 3.13Å; T153-K155 PolarHBondContact OG1-N 3.14Å; T153-G156 PolarHBondContact O-N 2.84Å; T153-G156 PolarHBondContact OG1-N 3.13Å; T153-G156 VanDerWaalsContact OG1-N 3.1Å; T153-H157 WeakPolarHBondContact O-CB 3.41Å; T153-H157 PolarHBondContact O-N 3.14Å; T153-P223 HydrophobicContact CG2-CB 4.3Å; T153-P223 HydrophobicContact CG2-CG 3.52Å
154V98.3Very high97.7Very high0 Ų027.7 Ų27.70%015%0.147CC..Hα-helixtrans-52.2-34.7168.8170.90000111.5L142 G158 R186 Y190 I221L142-V154 HydrophobicContact CD1-CG2 4.28Å; V154-G158 PolarHBondContact O-N 3Å; V154-R186 HydrophobicContact CG2-CB 4.14Å; V154-Y190 HydrophobicContact CG1-CD1 3.61Å; V154-Y190 HydrophobicContact CG1-CG 3.76Å; V154-Y190 VanDerWaalsContact O-CD1 3.31Å; V154-Y190 WeakPolarHBondContact O-CD1 3.48Å; V154-Y190 WeakPolarHBondContact O-CE1 3.18Å; V154-I221 HydrophobicContact CG2-CD1 4.16Å; V154-I221 HydrophobicContact CG2-CG1 4.08Å
155K98Very high97.8Very high103 Ų10329.7 Ų29.745%0.44814%0.138SC..Hα-helixtrans-70.6-44.9176.1-67-175.2-179.7178.60111.9T153 G158 K159 H220T153-K155 PolarHBondContact O-N 2.79Å; T153-K155 VanDerWaalsContact O-N 3.13Å; T153-K155 PolarHBondContact OG1-N 3.14Å; K155-G158 PolarHBondContact O-N 2.75Å; K155-K159 WeakPolarHBondContact O-CG 3.25Å; K155-K159 PolarHBondContact O-N 3.09Å; K155-H220 WeakPolarHBondContact CE-CD2 3.38Å; K155-H220 WeakPolarHBondContact CE-NE2 3.37Å; K155-H220 HydrophobicContact CG-CB 4.44Å; K155-H220 WeakPolarHBondContact CG-ND1 3.23Å
156G98.2Very high97.8Very high5 Ų534.1 Ų34.15%0.05216%0.156CC..Hα-helixtrans-61.3-44.7177.200000112.4D110 T153 K159D110-G156 VanDerWaalsContact CG-CA 3.44Å; D110-G156 WeakPolarHBondContact OD1-CA 3.22Å; D110-G156 PolarHBondContact OD2-N 2.93Å; T153-G156 PolarHBondContact O-N 2.84Å; T153-G156 PolarHBondContact OG1-N 3.13Å; T153-G156 VanDerWaalsContact OG1-N 3.1Å; G156-K159 WeakPolarHBondContact O-CB 3.28Å; G156-K159 PolarHBondContact O-N 2.9Å
157H98.6Very high97.9Very high0 Ų031.5 Ų31.50%015%0.149CC..Hα-helixtrans-61.3-52.1175.5-154.7-87.5000111.2V51 G138 S141 L142 T153 K159 C160 E191V51-H157 VanDerWaalsContact CG2-CE1 3.41Å; V51-H157 WeakPolarHBondContact CG2-CE1 3.41Å; V51-H157 VanDerWaalsContact CG2-NE2 3.28Å; V51-H157 WeakPolarHBondContact CG2-NE2 3.33Å; G138-H157 PolarHBondContact O-NE2 3.43Å; S141-H157 PolarHBondContact OG-CD2 3.02Å; S141-H157 PolarHBondContact OG-NE2 3.1Å; S141-H157 VanDerWaalsContact OG-NE2 3.14Å; L142-H157 HydrophobicContact CD2-CB 3.89Å; T153-H157 WeakPolarHBondContact O-CB 3.41Å; T153-H157 PolarHBondContact O-N 3.14Å; H157-K159 VanDerWaalsContact C-N 3.26Å; H157-K159 PolarHBondContact O-N 2.82Å; H157-C160 WeakPolarHBondContact O-CB 3.42Å; H157-C160 PolarHBondContact O-N 3.19Å; H157-E191 IonicContact CE1-OE1 3.8Å; H157-E191 PolarHBondContact CE1-OE1 3.27Å; H157-E191 IonicContact CG-OE1 2.86Å; H157-E191 IonicContact ND1-OE1 3.06Å; H157-E191 PolarHBondContact ND1-OE1 2.86Å
158G98.6Very high97.9Very high1 Ų135.7 Ų35.71%0.0117%0.171CC..Hα-helixtrans-64.4-23178.300000114.8V154 K155 C160 V161 E162V154-G158 PolarHBondContact O-N 3Å; K155-G158 PolarHBondContact O-N 2.75Å; G158-C160 PolarHBondContact O-N 3.43Å; G158-V161 PolarHBondContact O-N 3.34Å; G158-E162 WeakPolarHBondContact O-CB 3.49Å; G158-E162 PolarHBondContact O-N 3.14Å
159K98.5Very high98.1Very high71 Ų7137.6 Ų37.631%0.30918%0.179SC..Hα-helixtrans-63-29.5169.7-82.4178.5173.1-173.70112.2E114 K155 G156 H157 E162 F163E114-K159 WeakPolarHBondContact OE2-CD 3.32Å; E114-K159 IonicContact OE2-NZ 3.95Å; E114-K159 PolarHBondContact OE2-NZ 3.3Å; K155-K159 WeakPolarHBondContact O-CG 3.25Å; K155-K159 PolarHBondContact O-N 3.09Å; G156-K159 WeakPolarHBondContact O-CB 3.28Å; G156-K159 PolarHBondContact O-N 2.9Å; H157-K159 VanDerWaalsContact C-N 3.26Å; H157-K159 PolarHBondContact O-N 2.82Å; K159-E162 PolarHBondContact O-N 2.85Å; K159-F163 VanDerWaalsContact O-CB 3.29Å; K159-F163 WeakPolarHBondContact O-CB 3.41Å; K159-F163 PolarHBondContact O-N 2.99Å
160C98.8Very high98.2Very high4 Ų438.2 Ų38.23%0.02718%0.182CC..Hα-helixtrans-66.9-47.8175.4-56.60000110.1V51 Y113 F117 M135 H157 G158 E162 F163 I164V51-C160 HydrophobicContact CG1-CB 4.37Å; Y113-C160 WeakPolarHBondContact CE1-SG 3.44Å; F117-C160 HydrophobicContact CD1-CB 4.25Å; F117-C160 HydrophobicContact CE1-CB 3.72Å; F117-C160 HydrophobicContact CE2-CB 4.12Å; F117-C160 HydrophobicContact CZ-CB 3.65Å; M135-C160 HydrophobicContact CE-CB 3.77Å; H157-C160 WeakPolarHBondContact O-CB 3.42Å; H157-C160 PolarHBondContact O-N 3.19Å; G158-C160 PolarHBondContact O-N 3.43Å; C160-E162 VanDerWaalsContact C-N 3.34Å; C160-E162 PolarHBondContact O-N 2.96Å; C160-F163 PolarHBondContact O-N 3.23Å; C160-I164 WeakPolarHBondContact O-CG1 3.12Å; C160-I164 PolarHBondContact O-N 2.89Å
161V98.7Very high98.2Very high0 Ų038.6 Ų38.60%018%0.184CC..Hα-helixtrans-61.2-43.1173.8178.70000111M135 G158 F163 I164 R165 L173 E191 V194M135-V161 HydrophobicContact CE-CG2 3.77Å; M135-V161 HydrophobicContact SD-CG2 4Å; G158-V161 PolarHBondContact O-N 3.34Å; V161-F163 VanDerWaalsContact C-N 3.31Å; V161-F163 PolarHBondContact O-N 3Å; V161-I164 PolarHBondContact O-N 3.46Å; V161-R165 VanDerWaalsContact O-CB 3.23Å; V161-R165 WeakPolarHBondContact O-CB 3.37Å; V161-R165 PolarHBondContact O-N 2.75Å; V161-L173 HydrophobicContact CG1-CD1 4.02Å; V161-L173 HydrophobicContact CG1-CD2 4.32Å; V161-E191 HydrophobicContact CG2-CB 4.3Å; V161-E191 HydrophobicContact CG2-CG 3.92Å; V161-E191 WeakPolarHBondContact CG2-OE1 3.24Å; V161-V194 HydrophobicContact CB-CG1 4.29Å; V161-V194 HydrophobicContact CG1-CB 4.43Å; V161-V194 HydrophobicContact CG1-CG1 3.99Å
162E98.6Very high98.3Very high75 Ų7539.8 Ų39.835%0.3519%0.191SC..Hα-helixtrans-59.9-43.1177.5-164.9-163.2176.600111.3G158 K159 C160 K166 V194G158-E162 WeakPolarHBondContact O-CB 3.49Å; G158-E162 PolarHBondContact O-N 3.14Å; K159-E162 PolarHBondContact O-N 2.85Å; C160-E162 VanDerWaalsContact C-N 3.34Å; C160-E162 PolarHBondContact O-N 2.96Å; E162-K166 VanDerWaalsContact O-CG 3.3Å; E162-K166 WeakPolarHBondContact O-CG 3.37Å; E162-K166 PolarHBondContact O-N 3.03Å; E162-K166 VanDerWaalsContact O-N 3.14Å; E162-K166 VanDerWaalsContact OE1-CE 3.31Å; E162-K166 WeakPolarHBondContact OE1-CE 3.45Å; E162-K166 IonicContact OE1-NZ 3.35Å; E162-K166 PolarHBondContact OE1-NZ 3.34Å; E162-K166 IonicContact OE2-NZ 2.69Å; E162-V194 HydrophobicContact CB-CG1 3.68Å; E162-V194 HydrophobicContact CG-CG1 4.15Å
163F98.8Very high98.3Very high24 Ų2439.8 Ų39.811%0.10519%0.191CC..Hα-helixtrans-66.1-44.6178.4179.3-95.2000112.3F117 Q118 V121 T122 K159 C160 V161 K166 Q167F117-F163 HydrophobicContact CD1-CD1 4.22Å; F117-F163 HydrophobicContact CE1-CB 4.4Å; F117-F163 AromaticContact CE1-CD1 3.87Å; F117-F163 HydrophobicContact CE1-CD1 3.87Å; F117-F163 HydrophobicContact CE1-CG 4.48Å; Q118-F163 HydrophobicContact CB-CD2 4.08Å; Q118-F163 HydrophobicContact CB-CE1 4.48Å; Q118-F163 HydrophobicContact CB-CE2 3.8Å; Q118-F163 HydrophobicContact CB-CZ 4.04Å; Q118-F163 HydrophobicContact CG-CD1 4.43Å; Q118-F163 HydrophobicContact CG-CD2 3.58Å; Q118-F163 HydrophobicContact CG-CE2 3.84Å; Q118-F163 HydrophobicContact CG-CG 3.91Å; Q118-F163 HydrophobicContact CG-CZ 4.4Å; V121-F163 HydrophobicContact CB-CD1 4.46Å; V121-F163 HydrophobicContact CB-CE1 3.85Å; V121-F163 HydrophobicContact CG1-CD1 4.2Å; V121-F163 HydrophobicContact CG1-CE1 3.66Å; T122-F163 VanDerWaalsContact OG1-CZ 3.32Å; T122-F163 WeakPolarHBondContact OG1-CZ 3.38Å; K159-F163 VanDerWaalsContact O-CB 3.29Å; K159-F163 WeakPolarHBondContact O-CB 3.41Å; K159-F163 PolarHBondContact O-N 2.99Å; C160-F163 PolarHBondContact O-N 3.23Å; V161-F163 VanDerWaalsContact C-N 3.31Å; V161-F163 PolarHBondContact O-N 3Å; F163-K166 PolarHBondContact O-N 3.43Å; F163-Q167 PolarHBondContact O-NE2 2.64Å
164I98.7Very high98.3Very high3 Ų339.6 Ų39.62%0.01519%0.189CC..Hα-helixtrans-64.2-44.2176.8-70-70.5000110.8V49 F117 V121 I133 M135 C160 V161 K166 Q167 L171V49-I164 HydrophobicContact CG2-CD1 4.14Å; F117-I164 HydrophobicContact CE1-CG1 4.3Å; F117-I164 HydrophobicContact CZ-CD1 4.37Å; F117-I164 HydrophobicContact CZ-CG1 4.1Å; V121-I164 HydrophobicContact CG1-CD1 3.58Å; I133-I164 HydrophobicContact CD1-CD1 4.28Å; I133-I164 HydrophobicContact CD1-CG2 4.04Å; I133-I164 HydrophobicContact CG2-CG2 3.97Å; M135-I164 HydrophobicContact CE-CG1 4.48Å; M135-I164 HydrophobicContact SD-CB 4.05Å; M135-I164 HydrophobicContact SD-CG1 3.77Å; M135-I164 HydrophobicContact SD-CG2 4.22Å; C160-I164 WeakPolarHBondContact O-CG1 3.12Å; C160-I164 PolarHBondContact O-N 2.89Å; V161-I164 PolarHBondContact O-N 3.46Å; I164-K166 VanDerWaalsContact C-N 3.26Å; I164-K166 PolarHBondContact O-N 3.5Å; I164-Q167 VanDerWaalsContact O-CB 3.27Å; I164-Q167 WeakPolarHBondContact O-CB 3.35Å; I164-Q167 VanDerWaalsContact O-CG 3.27Å; I164-Q167 WeakPolarHBondContact O-CG 3.3Å; I164-Q167 PolarHBondContact O-N 2.69Å; I164-L171 HydrophobicContact CG2-CD1 3.55Å; I164-L171 HydrophobicContact CG2-CD2 3.99Å; I164-L171 HydrophobicContact CG2-CG 4.42Å
165R97.9Very high98.3Very high94 Ų9439.6 Ų39.636%0.35519%0.189SC..Hα-helixtrans-57.3-38.4176.2179.5179.7173.5-85-1.3112.3I7 V161 Q167 N168 V194 A195I7-R165 HydrophobicContact CD1-CG 4.25Å; V161-R165 VanDerWaalsContact O-CB 3.23Å; V161-R165 WeakPolarHBondContact O-CB 3.37Å; V161-R165 PolarHBondContact O-N 2.75Å; R165-Q167 PolarHBondContact O-N 3.14Å; R165-Q167 VanDerWaalsContact O-N 3.13Å; R165-N168 PolarHBondContact O-N 3.08Å; R165-V194 WeakPolarHBondContact CD-O 3.2Å; R165-V194 PolarHBondContact NE-O 3.41Å; R165-A195 WeakPolarHBondContact CD-O 3.44Å; R165-A195 PolarHBondContact NE-O 2.92Å
166K98Very high98.3Very high110 Ų11035.8 Ų35.848%0.47818%0.179SC..THydrogen-bonded Turntrans-64.7-12.1177.9-76.2167.4-176.61650114E162 F163 I164 N168E162-K166 VanDerWaalsContact O-CG 3.3Å; E162-K166 WeakPolarHBondContact O-CG 3.37Å; E162-K166 PolarHBondContact O-N 3.03Å; E162-K166 VanDerWaalsContact O-N 3.14Å; E162-K166 VanDerWaalsContact OE1-CE 3.31Å; E162-K166 WeakPolarHBondContact OE1-CE 3.45Å; E162-K166 IonicContact OE1-NZ 3.35Å; E162-K166 PolarHBondContact OE1-NZ 3.34Å; E162-K166 IonicContact OE2-NZ 2.69Å; F163-K166 PolarHBondContact O-N 3.43Å; I164-K166 VanDerWaalsContact C-N 3.26Å; I164-K166 PolarHBondContact O-N 3.5Å; K166-N168 PolarHBondContact O-N 3.46Å; K166-N168 PolarHBondContact O-ND2 3.42Å; K166-N168 VanDerWaalsContact O-ND2 3.14Å
167Q97.8Very high98.2Very high57 Ų5736 Ų3627%0.26618%0.182SC..THydrogen-bonded Turntrans-77-11.4177.2-49.9-54.4-49.800112.9I125 F163 I164 R165 L169I125-Q167 HydrophobicContact CD1-CB 4.21Å; I125-Q167 HydrophobicContact CD1-CG 3.6Å; F163-Q167 PolarHBondContact O-NE2 2.64Å; I164-Q167 VanDerWaalsContact O-CB 3.27Å; I164-Q167 WeakPolarHBondContact O-CB 3.35Å; I164-Q167 VanDerWaalsContact O-CG 3.27Å; I164-Q167 WeakPolarHBondContact O-CG 3.3Å; I164-Q167 PolarHBondContact O-N 2.69Å; R165-Q167 PolarHBondContact O-N 3.14Å; R165-Q167 VanDerWaalsContact O-N 3.13Å; Q167-L169 PolarHBondContact O-N 3.45Å
168N96.4Very high98.2Very high145 Ų14537 Ų3778%0.77519%0.193SC*.  trans54.437.1178.3-52.3-65.5000113.7R165 K166R165-N168 PolarHBondContact O-N 3.08Å; K166-N168 PolarHBondContact O-N 3.46Å; K166-N168 PolarHBondContact O-ND2 3.42Å; K166-N168 VanDerWaalsContact O-ND2 3.14Å
169L97.6Very high98.1Very high51 Ų5140 Ų4027%0.26720%0.204SC..SBendtrans-103.4149.9170-68.7173.8000109.5P130 I133 Q167 L171P130-L169 HydrophobicContact CG-CD1 3.98Å; I133-L169 HydrophobicContact CD1-CB 4.42Å; I133-L169 HydrophobicContact CD1-CD1 3.94Å; I133-L169 HydrophobicContact CG1-CB 4.41Å; I133-L169 HydrophobicContact CG1-CD1 4.08Å; Q167-L169 PolarHBondContact O-N 3.45Å; L169-L171 PolarHBondContact O-N 2.85Å
170P98.1Very high98Very high46 Ų4637.3 Ų37.330%0.29919%0.193SC..  trans-47132.3166.6-27.333.8000110.9D6 F43 E131 V132 I133D6-P170 WeakPolarHBondContact O-CA 3.44Å; F43-P170 HydrophobicContact CE1-CG 4.5Å; F43-P170 HydrophobicContact CZ-CG 4.43Å; E131-P170 VanDerWaalsContact O-CD 3.31Å; E131-P170 WeakPolarHBondContact O-CD 3.5Å; V132-P170 WeakPolarHBondContact CA-O 3.32Å; V132-P170 HydrophobicContact CB-CB 4.25Å; V132-P170 HydrophobicContact CG2-CB 4.06Å; V132-P170 WeakPolarHBondContact CG2-O 3.41Å; I133-P170 PolarHBondContact N-O 2.92Å
171L98.6Very high97.8Very high9 Ų941.3 Ų41.35%0.04722%0.218CC..EExtended strand (participates in β ladder)trans-131.2129.5-169.7-179.859.4000111.2D6 I7 A8 I133 M135 I164 L169 L173D6-L171 PolarHBondContact O-N 3.21Å; I7-L171 CarbonylContact C-O 3.54Å; I7-L171 VanDerWaalsContact CA-O 3.28Å; I7-L171 WeakPolarHBondContact CA-O 3.47Å; I7-L171 HydrophobicContact CD1-CD2 4.5Å; I7-L171 HydrophobicContact CG1-CB 4.24Å; I7-L171 HydrophobicContact CG2-CB 4.32Å; I7-L171 HydrophobicContact CG2-CD2 4.31Å; I7-L171 HydrophobicContact CG2-CG 4.34Å; A8-L171 PolarHBondContact N-O 3.29Å; I133-L171 HydrophobicContact CB-CD1 3.94Å; I133-L171 HydrophobicContact CG2-CD1 3.84Å; I133-L171 WeakPolarHBondContact O-CA 3.32Å; M135-L171 HydrophobicContact CB-CD1 4.12Å; I164-L171 HydrophobicContact CG2-CD1 3.55Å; I164-L171 HydrophobicContact CG2-CD2 3.99Å; I164-L171 HydrophobicContact CG2-CG 4.42Å; L169-L171 PolarHBondContact O-N 2.85Å; L171-L173 HydrophobicContact CD1-CD2 3.97Å; L171-L173 HydrophobicContact CD2-CD2 3.8Å; L171-L173 HydrophobicContact CD2-CG 4.2Å; L171-L173 HydrophobicContact CG-CD2 3.85Å; L171-L173 HydrophobicContact CG-CG 4.15Å
172L98.6Very high97.6Very high30 Ų3046.1 Ų46.116%0.15724%0.236CC..EExtended strand (participates in β ladder)trans-110.4115.9166.6174.160.4000108.5A8 A35 I133 V134 M135 L174A8-L172 HydrophobicContact CB-CD1 3.92Å; A8-L172 CarbonylContact O-C 3.52Å; A8-L172 WeakPolarHBondContact O-CA 3.05Å; A35-L172 HydrophobicContact CB-CD2 4Å; I133-L172 PolarHBondContact O-N 3.48Å; V134-L172 CarbonylContact C-O 3.44Å; V134-L172 WeakPolarHBondContact CA-O 3.4Å; V134-L172 HydrophobicContact CG1-CD2 4.18Å; V134-L172 HydrophobicContact CG1-CG 4.42Å; V134-L172 HydrophobicContact CG2-CB 4.32Å; V134-L172 HydrophobicContact CG2-CD2 4.31Å; M135-L172 PolarHBondContact N-O 3.47Å; L172-L174 HydrophobicContact CD1-CD2 3.96Å; L172-L174 HydrophobicContact CD2-CD2 4.08Å; L172-L174 HydrophobicContact CD2-CG 4.49Å; L172-L174 HydrophobicContact CG-CD2 3.84Å; L172-L174 HydrophobicContact CG-CG 4.13Å
173L98.8Very high97.5Very high0 Ų043.2 Ų43.20%022%0.223CC..EExtended strand (participates in β ladder)trans-94133.9172.2-60-179.6000109.8I7 A8 I9 N10 W11 M135 V161 L171 A195I7-L173 HydrophobicContact CG2-CD1 4.37Å; I7-L173 HydrophobicContact CG2-CG 4.41Å; A8-L173 PolarHBondContact O-N 2.68Å; I9-L173 CarbonylContact C-O 3.58Å; I9-L173 WeakPolarHBondContact CA-O 2.95Å; I9-L173 HydrophobicContact CG1-CB 4.17Å; I9-L173 HydrophobicContact CG1-CD1 4.18Å; N10-L173 PolarHBondContact N-O 3.31Å; W11-L173 HydrophobicContact CH2-CB 3.96Å; W11-L173 HydrophobicContact CH2-CD1 4.03Å; W11-L173 HydrophobicContact CZ3-CB 4.09Å; M135-L173 HydrophobicContact CB-CD2 3.88Å; M135-L173 HydrophobicContact CG-CD2 4.36Å; M135-L173 WeakPolarHBondContact O-CA 3.46Å; M135-L173 HydrophobicContact SD-CD2 4.14Å; V161-L173 HydrophobicContact CG1-CD1 4.02Å; V161-L173 HydrophobicContact CG1-CD2 4.32Å; L171-L173 HydrophobicContact CD1-CD2 3.97Å; L171-L173 HydrophobicContact CD2-CD2 3.8Å; L171-L173 HydrophobicContact CD2-CG 4.2Å; L171-L173 HydrophobicContact CG-CD2 3.85Å; L171-L173 HydrophobicContact CG-CG 4.15Å; L173-A195 HydrophobicContact CD1-CB 3.85Å
174L98.8Very high97.5Very high3 Ų342.9 Ų42.92%0.01622%0.222CC..EExtended strand (participates in β ladder)trans-122.9158179.5-57.5176000109.7N10 I32 V134 M135 C137 L172N10-L174 HydrophobicContact CB-CD2 3.92Å; N10-L174 WeakPolarHBondContact O-CA 3.09Å; I32-L174 HydrophobicContact CB-CD1 4.24Å; I32-L174 HydrophobicContact CG1-CD1 3.61Å; I32-L174 HydrophobicContact CG2-CD1 4.17Å; V134-L174 HydrophobicContact CG1-CD1 3.62Å; V134-L174 HydrophobicContact CG1-CG 4.36Å; M135-L174 PolarHBondContact O-N 2.92Å; C137-L174 VanDerWaalsContact CB-O 3.22Å; C137-L174 WeakPolarHBondContact CB-O 3.47Å; C137-L174 PolarHBondContact N-O 3.4Å; L172-L174 HydrophobicContact CD1-CD2 3.96Å; L172-L174 HydrophobicContact CD2-CD2 4.08Å; L172-L174 HydrophobicContact CD2-CG 4.49Å; L172-L174 HydrophobicContact CG-CD2 3.84Å; L172-L174 HydrophobicContact CG-CG 4.13Å
175G98.4Very high97.4Very high0 Ų044.2 Ų44.20%023%0.234CC..  trans-71-142.3168.200000111.8N10 W11 G13 Q136 C137N10-G175 PolarHBondContact O-N 3.09Å; W11-G175 WeakPolarHBondContact O-CA 3.31Å; G13-G175 CarbonylContact O-C 3.58Å; G13-G175 VanDerWaalsContact O-C 3.29Å; G13-G175 WeakPolarHBondContact O-CA 3.41Å; G13-G175 PolarHBondContact O-N 2.69Å; Q136-G175 WeakPolarHBondContact CG-O 3.3Å; Q136-G175 PolarHBondContact NE2-O 3.3Å; C137-G175 PolarHBondContact N-O 2.84Å
176G97.5Very high97.4Very high23 Ų2340.1 Ų40.124%0.23722%0.218CC..  trans156.8-160.3-175.100000112.5G13G13-G176 PolarHBondContact O-N 3.05Å
177G96.6Very high97.4Very high11 Ų1134.9 Ų34.911%0.11320%0.196CC..  trans-61.7159.3172.200000112.2D52 G138 A139 D140D52-G177 PolarHBondContact OD2-N 3.34Å; G138-G177 CarbonylContact C-O 3.59Å; G138-G177 WeakPolarHBondContact CA-O 3.09Å; A139-G177 PolarHBondContact N-O 2.99Å; D140-G177 PolarHBondContact N-O 3.06Å
178G97.3Very high97.4Very high21 Ų2134.3 Ų34.322%0.21619%0.191CC..  trans162.195.5-175.600000110.9V184G178-V184 WeakPolarHBondContact O-CG2 3.44Å
179Y97Very high97.5Very high62 Ų6231 Ų3124%0.24318%0.177CC..SBendtrans-105.94.8-166.9-53.6-85.3000112.5F26 D140 D145 L147F26-Y179 HydrophobicContact CD2-CE1 4.04Å; F26-Y179 WeakPolarHBondContact CD2-OH 3.35Å; F26-Y179 AromaticContact CE2-CE1 3.91Å; F26-Y179 HydrophobicContact CE2-CE1 3.91Å; D140-Y179 HydrophobicContact CB-CD2 3.96Å; D140-Y179 HydrophobicContact CB-CE2 4.05Å; D145-Y179 PolarHBondContact OD1-N 2.8Å; L147-Y179 HydrophobicContact CB-CD2 3.65Å; L147-Y179 HydrophobicContact CB-CE2 3.99Å; L147-Y179 HydrophobicContact CB-CG 4.14Å; L147-Y179 HydrophobicContact CD1-CD1 3.64Å; L147-Y179 HydrophobicContact CD1-CD2 3.75Å; L147-Y179 HydrophobicContact CD1-CE1 3.61Å; L147-Y179 HydrophobicContact CD1-CE2 3.74Å; L147-Y179 HydrophobicContact CD1-CG 3.7Å; L147-Y179 HydrophobicContact CG-CD1 4.15Å; L147-Y179 HydrophobicContact CG-CD2 3.75Å; L147-Y179 HydrophobicContact CG-CE2 4.19Å; L147-Y179 HydrophobicContact CG-CG 3.72Å
180T96.3Very high97.6Very high15 Ų1530.9 Ų30.99%0.09217%0.173CC..SBendtrans-114.288.6163.2-60.60000109.3G144 D145 R182 N183 V184G144-T180 PolarHBondContact O-OG1 3.3Å; D145-T180 PolarHBondContact OD1-N 3.12Å; T180-R182 VanDerWaalsContact C-N 3.28Å; T180-R182 HydrophobicContact CG2-CG 3.82Å; T180-R182 PolarHBondContact O-N 3.33Å; T180-R182 VanDerWaalsContact O-N 3.11Å; T180-N183 HydrophobicContact CG2-CB 4.07Å; T180-N183 WeakPolarHBondContact O-CA 3.43Å; T180-N183 WeakPolarHBondContact O-CB 3.29Å; T180-N183 PolarHBondContact O-N 2.64Å; T180-V184 PolarHBondContact O-N 3.27Å; T180-V184 VanDerWaalsContact O-N 3.12Å
181V95Very high97.6Very high89 Ų8928.7 Ų28.754%0.53916%0.159SC..Hα-helixtrans-51-42-168.1-179.90000113.5N183 V184 A185 Y288V181-N183 VanDerWaalsContact C-N 3.26Å; V181-N183 PolarHBondContact O-N 3.22Å; V181-V184 WeakPolarHBondContact O-CB 3.35Å; V181-V184 PolarHBondContact O-N 2.98Å; V181-A185 PolarHBondContact O-N 3.03Å; V181-Y288 HydrophobicContact CG2-CD1 4.07Å; V181-Y288 HydrophobicContact CG2-CE1 4.09Å
182R94.9Very high97.6Very high100 Ų10030.2 Ų30.238%0.37717%0.169SC..Hα-helixtrans-60.3-33.3176.362.4-176.5-179.5178.3-5.2113.5T180 R186 Y212 Y213T180-R182 VanDerWaalsContact C-N 3.28Å; T180-R182 HydrophobicContact CG2-CG 3.82Å; T180-R182 PolarHBondContact O-N 3.33Å; T180-R182 VanDerWaalsContact O-N 3.11Å; R182-R186 VanDerWaalsContact O-CG 3.32Å; R182-R186 WeakPolarHBondContact O-CG 3.37Å; R182-R186 PolarHBondContact O-N 3.29Å; R182-Y212 WeakPolarHBondContact CD-O 3.4Å; R182-Y213 HydrophobicContact CB-CD1 4.18Å; R182-Y213 HydrophobicContact CB-CE1 4.06Å; R182-Y213 WeakPolarHBondContact O-CE1 3.08Å
183N96.3Very high97.6Very high15 Ų1529 Ų298%0.0816%0.162CC..Hα-helixtrans-80.5-33.6177.7-70.2-9.1000111.4L142 T180 V181 R186 C187L142-N183 HydrophobicContact CD1-CB 4.26Å; T180-N183 HydrophobicContact CG2-CB 4.07Å; T180-N183 WeakPolarHBondContact O-CA 3.43Å; T180-N183 WeakPolarHBondContact O-CB 3.29Å; T180-N183 PolarHBondContact O-N 2.64Å; V181-N183 VanDerWaalsContact C-N 3.26Å; V181-N183 PolarHBondContact O-N 3.22Å; N183-R186 PolarHBondContact O-N 2.93Å; N183-R186 PolarHBondContact OD1-NH1 3.14Å; N183-C187 WeakPolarHBondContact O-CB 3.33Å; N183-C187 PolarHBondContact O-N 3.14Å
184V97.9Very high97.6Very high16 Ų1629.8 Ų29.810%0.09717%0.167CC..Hα-helixtrans-56.3-51.5169.4-178.80000110.3A139 G178 T180 V181 R186 C187 W188A139-V184 HydrophobicContact CB-CB 4.44Å; A139-V184 HydrophobicContact CB-CG2 4.1Å; G178-V184 WeakPolarHBondContact O-CG2 3.44Å; T180-V184 PolarHBondContact O-N 3.27Å; T180-V184 VanDerWaalsContact O-N 3.12Å; V181-V184 WeakPolarHBondContact O-CB 3.35Å; V181-V184 PolarHBondContact O-N 2.98Å; V184-R186 VanDerWaalsContact C-N 3.34Å; V184-R186 PolarHBondContact O-N 3.33Å; V184-C187 PolarHBondContact O-N 2.88Å; V184-C187 VanDerWaalsContact O-N 3.14Å; V184-W188 HydrophobicContact CG1-CD2 3.61Å; V184-W188 HydrophobicContact CG1-CE3 3.45Å; V184-W188 VanDerWaalsContact CG1-CE3 3.45Å; V184-W188 HydrophobicContact CG1-CG 4.49Å; V184-W188 HydrophobicContact CG1-CH2 3.47Å; V184-W188 VanDerWaalsContact CG1-CH2 3.47Å; V184-W188 HydrophobicContact CG1-CZ2 3.6Å; V184-W188 HydrophobicContact CG1-CZ3 3.39Å; V184-W188 PolarHBondContact O-N 3.25Å
185A96.9Very high97.5Very high31 Ų3129.9 Ų29.926%0.25617%0.169SC..Hα-helixtrans-59.1-43.4178.800000112.4V181 T189 Y213V181-A185 PolarHBondContact O-N 3.03Å; A185-T189 WeakPolarHBondContact O-CB 3.45Å; A185-T189 PolarHBondContact O-N 3.5Å; A185-T189 VanDerWaalsContact O-N 3.12Å; A185-T189 PolarHBondContact O-OG1 3.38Å; A185-Y213 HydrophobicContact CB-CE1 4.4Å; A185-Y213 WeakPolarHBondContact CB-OH 3.39Å
186R97.5Very high97.5Very high8 Ų834.8 Ų34.83%0.0319%0.193CC..Hα-helixtrans-60.5-47.1173.9-75170.4172.6124.4-4112V154 R182 N183 V184 Y190 Y213 D216 K218 L219V154-R186 HydrophobicContact CG2-CB 4.14Å; R182-R186 VanDerWaalsContact O-CG 3.32Å; R182-R186 WeakPolarHBondContact O-CG 3.37Å; R182-R186 PolarHBondContact O-N 3.29Å; N183-R186 PolarHBondContact O-N 2.93Å; N183-R186 PolarHBondContact OD1-NH1 3.14Å; V184-R186 VanDerWaalsContact C-N 3.34Å; V184-R186 PolarHBondContact O-N 3.33Å; R186-Y190 WeakPolarHBondContact O-CB 3.5Å; R186-Y190 PolarHBondContact O-N 3.24Å; R186-Y213 HydrophobicContact CG-CD1 4.27Å; R186-Y213 HydrophobicContact CG-CE1 4.19Å; R186-Y213 PolarHBondContact NH2-O 3.37Å; R186-Y213 VanDerWaalsContact NH2-O 3.11Å; R186-D216 IonicContact NH2-OD1 3.47Å; R186-D216 PolarHBondContact NH2-OD1 3.05Å; R186-K218 PolarHBondContact NE-O 2.68Å; R186-K218 PolarHBondContact NH2-O 2.84Å; R186-L219 HydrophobicContact CB-CD1 4.21Å; R186-L219 WeakPolarHBondContact CB-O 3.46Å; R186-L219 WeakPolarHBondContact CD-O 3.35Å; R186-L219 HydrophobicContact CG-CD1 4.43Å; R186-L219 WeakPolarHBondContact CG-O 3.49Å; R186-L219 WeakPolarHBondContact O-CD1 3.43Å
187C98.5Very high97.4Very high0 Ų036 Ų360%021%0.206CC..Hα-helixtrans-60.8-59.4-177-161.10000111.3A139 L142 N183 V184 T189 Y190 E191A139-C187 HydrophobicContact CB-CB 4.11Å; L142-C187 HydrophobicContact CD1-CB 3.78Å; N183-C187 WeakPolarHBondContact O-CB 3.33Å; N183-C187 PolarHBondContact O-N 3.14Å; V184-C187 PolarHBondContact O-N 2.88Å; V184-C187 VanDerWaalsContact O-N 3.14Å; C187-T189 VanDerWaalsContact C-N 3.29Å; C187-T189 PolarHBondContact O-N 3.4Å; C187-Y190 CarbonylContact O-C 3.18Å; C187-Y190 WeakPolarHBondContact O-CA 3.31Å; C187-Y190 WeakPolarHBondContact O-CB 3.46Å; C187-Y190 PolarHBondContact O-N 3.37Å; C187-E191 WeakPolarHBondContact O-CG 3.49Å; C187-E191 PolarHBondContact O-N 3.04Å
188W98.7Very high97.5Very high45 Ų4540.9 Ų40.917%0.1723%0.227CC..Hα-helixtrans-68.5-28-174.9-62-18.8000112.6W11 C137 V184 T192W11-W188 HydrophobicContact CB-CD2 4.21Å; W11-W188 HydrophobicContact CB-CE3 3.7Å; W11-W188 HydrophobicContact CB-CZ3 3.99Å; W11-W188 HydrophobicContact CD2-CB 3.89Å; W11-W188 HydrophobicContact CD2-CD2 4.22Å; W11-W188 AromaticContact CD2-CG 3.95Å; W11-W188 HydrophobicContact CD2-CG 3.95Å; W11-W188 HydrophobicContact CE3-CB 4.24Å; W11-W188 AromaticContact CE3-CD1 3.92Å; W11-W188 HydrophobicContact CE3-CD2 4.12Å; W11-W188 AromaticContact CE3-CG 3.87Å; W11-W188 HydrophobicContact CE3-CG 3.87Å; W11-W188 HydrophobicContact CG-CB 4.21Å; W11-W188 HydrophobicContact CG-CD2 4.29Å; W11-W188 HydrophobicContact CG-CE3 4.13Å; W11-W188 HydrophobicContact CG-CG 4.36Å; W11-W188 HydrophobicContact CZ2-CB 4.35Å; W11-W188 HydrophobicContact CZ3-CG 4.32Å; W11-W188 VanDerWaalsContact O-CH2 3.28Å; W11-W188 WeakPolarHBondContact O-CH2 3.19Å; W11-W188 WeakPolarHBondContact O-CZ3 3.4Å; C137-W188 PolarHBondContact O-NE1 2.73Å; V184-W188 HydrophobicContact CG1-CD2 3.61Å; V184-W188 HydrophobicContact CG1-CE3 3.45Å; V184-W188 VanDerWaalsContact CG1-CE3 3.45Å; V184-W188 HydrophobicContact CG1-CG 4.49Å; V184-W188 HydrophobicContact CG1-CH2 3.47Å; V184-W188 VanDerWaalsContact CG1-CH2 3.47Å; V184-W188 HydrophobicContact CG1-CZ2 3.6Å; V184-W188 HydrophobicContact CG1-CZ3 3.39Å; V184-W188 PolarHBondContact O-N 3.25Å; W188-T192 VanDerWaalsContact O-CB 3.31Å; W188-T192 WeakPolarHBondContact O-CB 3.08Å; W188-T192 PolarHBondContact O-N 3.06Å; W188-T192 PolarHBondContact O-OG1 3.31Å
189T98.2Very high97.5Very high77 Ų7746.8 Ų46.847%0.47226%0.259SS..Hα-helixtrans-63.2-47.5168.8-62.30000111.1A185 C187 T192 S193 I200 L219A185-T189 WeakPolarHBondContact O-CB 3.45Å; A185-T189 PolarHBondContact O-N 3.5Å; A185-T189 VanDerWaalsContact O-N 3.12Å; A185-T189 PolarHBondContact O-OG1 3.38Å; C187-T189 VanDerWaalsContact C-N 3.29Å; C187-T189 PolarHBondContact O-N 3.4Å; T189-T192 PolarHBondContact O-N 2.86Å; T189-S193 PolarHBondContact O-N 2.83Å; T189-S193 VanDerWaalsContact O-N 3.14Å; T189-I200 HydrophobicContact CG2-CD1 4.12Å; T189-L219 HydrophobicContact CG2-CD1 4.42Å
190Y98.6Very high97.5Very high47 Ų4746.3 Ų46.318%0.18426%0.26CS..Hα-helixtrans-65.2-44.1178.2-178.6-116.6000111.7V154 R186 C187 T192 S193 V194 I200 L219 H220V154-Y190 HydrophobicContact CG1-CD1 3.61Å; V154-Y190 HydrophobicContact CG1-CG 3.76Å; V154-Y190 VanDerWaalsContact O-CD1 3.31Å; V154-Y190 WeakPolarHBondContact O-CD1 3.48Å; V154-Y190 WeakPolarHBondContact O-CE1 3.18Å; R186-Y190 WeakPolarHBondContact O-CB 3.5Å; R186-Y190 PolarHBondContact O-N 3.24Å; C187-Y190 CarbonylContact O-C 3.18Å; C187-Y190 WeakPolarHBondContact O-CA 3.31Å; C187-Y190 WeakPolarHBondContact O-CB 3.46Å; C187-Y190 PolarHBondContact O-N 3.37Å; Y190-T192 VanDerWaalsContact C-N 3.32Å; Y190-T192 PolarHBondContact O-N 3.49Å; Y190-S193 WeakPolarHBondContact O-CA 3.42Å; Y190-S193 WeakPolarHBondContact O-CB 3.27Å; Y190-S193 PolarHBondContact O-N 3.04Å; Y190-S193 PolarHBondContact O-OG 3.08Å; Y190-V194 HydrophobicContact CD1-CG2 4.36Å; Y190-V194 HydrophobicContact CE1-CG2 4Å; Y190-V194 HydrophobicContact CE2-CG2 4.31Å; Y190-V194 WeakPolarHBondContact O-CG2 3.39Å; Y190-V194 PolarHBondContact O-N 2.78Å; Y190-I200 HydrophobicContact CD2-CD1 4.49Å; Y190-L219 HydrophobicContact CD2-CD2 3.94Å; Y190-L219 HydrophobicContact CG-CD2 4.42Å; Y190-H220 AromaticContact CD2-CE1 3.57Å; Y190-H220 AromaticContact CE2-CE1 3.47Å; Y190-H220 VanDerWaalsContact CE2-CE1 3.47Å; Y190-H220 WeakPolarHBondContact CE2-CE1 3.5Å; Y190-H220 AromaticContact CG-CE1 3.95Å; Y190-H220 AromaticContact CZ-CE1 3.77Å
191E98.7Very high97.6Very high0 Ų050.4 Ų50.40%029%0.287CS..Hα-helixtrans-65.1-35.7177.9-68.7-174.914200112.9W11 C137 H157 V161 C187 S193 V194 A195W11-E191 HydrophobicContact CH2-CB 3.94Å; W11-E191 HydrophobicContact CZ2-CB 4.29Å; C137-E191 WeakPolarHBondContact CB-OE2 3.23Å; H157-E191 IonicContact CE1-OE1 3.8Å; H157-E191 PolarHBondContact CE1-OE1 3.27Å; H157-E191 IonicContact CG-OE1 2.86Å; H157-E191 IonicContact ND1-OE1 3.06Å; H157-E191 PolarHBondContact ND1-OE1 2.86Å; V161-E191 HydrophobicContact CG2-CB 4.3Å; V161-E191 HydrophobicContact CG2-CG 3.92Å; V161-E191 WeakPolarHBondContact CG2-OE1 3.24Å; C187-E191 WeakPolarHBondContact O-CG 3.49Å; C187-E191 PolarHBondContact O-N 3.04Å; E191-S193 VanDerWaalsContact C-N 3.28Å; E191-S193 PolarHBondContact O-N 2.74Å; E191-V194 PolarHBondContact O-N 3.3Å; E191-A195 WeakPolarHBondContact O-CB 3.46Å; E191-A195 PolarHBondContact O-N 2.64Å
192T98.7Very high97.7Very high42 Ų4249 Ų4926%0.25828%0.276SS..Hα-helixtrans-58.1-44.1169.7-59.60000110.4I9 W11 W188 T189 Y190 V194 A195 I196I9-T192 HydrophobicContact CD1-CG2 4.38Å; W11-T192 WeakPolarHBondContact CZ2-OG1 3.3Å; W11-T192 PolarHBondContact NE1-OG1 2.87Å; W11-T192 VanDerWaalsContact NE1-OG1 3.08Å; W188-T192 VanDerWaalsContact O-CB 3.31Å; W188-T192 WeakPolarHBondContact O-CB 3.08Å; W188-T192 PolarHBondContact O-N 3.06Å; W188-T192 PolarHBondContact O-OG1 3.31Å; T189-T192 PolarHBondContact O-N 2.86Å; Y190-T192 VanDerWaalsContact C-N 3.32Å; Y190-T192 PolarHBondContact O-N 3.49Å; T192-V194 VanDerWaalsContact C-N 3.34Å; T192-V194 PolarHBondContact O-N 3.39Å; T192-A195 WeakPolarHBondContact O-CB 3.33Å; T192-A195 PolarHBondContact O-N 2.82Å; T192-I196 WeakPolarHBondContact O-CG1 3.34Å; T192-I196 PolarHBondContact O-N 2.78Å; T192-I196 VanDerWaalsContact O-N 3.09Å
193S98.6Very high97.8Very high4 Ų449.1 Ų49.13%0.02829%0.285CS..Hα-helixtrans-63.1-39176.982.60000112.6T189 Y190 E191 I196 G197 M198T189-S193 PolarHBondContact O-N 2.83Å; T189-S193 VanDerWaalsContact O-N 3.14Å; Y190-S193 WeakPolarHBondContact O-CA 3.42Å; Y190-S193 WeakPolarHBondContact O-CB 3.27Å; Y190-S193 PolarHBondContact O-N 3.04Å; Y190-S193 PolarHBondContact O-OG 3.08Å; E191-S193 VanDerWaalsContact C-N 3.28Å; E191-S193 PolarHBondContact O-N 2.74Å; S193-I196 WeakPolarHBondContact O-CG1 3.47Å; S193-G197 PolarHBondContact O-N 2.78Å; S193-M198 CarbonylContact C-O 3.56Å; S193-M198 WeakPolarHBondContact CB-O 3.16Å; S193-M198 PolarHBondContact O-N 3.19Å
194V98.4Very high97.8Very high17 Ų1750 Ų5010%0.10329%0.289CS..Hα-helixtrans-65.4-44.9175.4174.20000110.7V161 E162 R165 Y190 E191 T192 I196 G197V161-V194 HydrophobicContact CB-CG1 4.29Å; V161-V194 HydrophobicContact CG1-CB 4.43Å; V161-V194 HydrophobicContact CG1-CG1 3.99Å; E162-V194 HydrophobicContact CB-CG1 3.68Å; E162-V194 HydrophobicContact CG-CG1 4.15Å; R165-V194 WeakPolarHBondContact CD-O 3.2Å; R165-V194 PolarHBondContact NE-O 3.41Å; Y190-V194 HydrophobicContact CD1-CG2 4.36Å; Y190-V194 HydrophobicContact CE1-CG2 4Å; Y190-V194 HydrophobicContact CE2-CG2 4.31Å; Y190-V194 WeakPolarHBondContact O-CG2 3.39Å; Y190-V194 PolarHBondContact O-N 2.78Å; E191-V194 PolarHBondContact O-N 3.3Å; T192-V194 VanDerWaalsContact C-N 3.34Å; T192-V194 PolarHBondContact O-N 3.39Å; V194-I196 PolarHBondContact O-N 2.56Å; V194-G197 PolarHBondContact O-N 3.14Å; V194-G197 VanDerWaalsContact O-N 3.1Å
195A98.1Very high97.7Very high5 Ų553.9 Ų53.94%0.04132%0.315CS..Hα-helixtrans-56.7-47.9178.700000111.4I7 I9 R165 L173 E191 T192 G197I7-A195 HydrophobicContact CD1-CB 4.48Å; I7-A195 WeakPolarHBondContact CD1-O 3.24Å; I7-A195 HydrophobicContact CG2-CB 4.36Å; I9-A195 HydrophobicContact CD1-CB 4.23Å; R165-A195 WeakPolarHBondContact CD-O 3.44Å; R165-A195 PolarHBondContact NE-O 2.92Å; L173-A195 HydrophobicContact CD1-CB 3.85Å; E191-A195 WeakPolarHBondContact O-CB 3.46Å; E191-A195 PolarHBondContact O-N 2.64Å; T192-A195 WeakPolarHBondContact O-CB 3.33Å; T192-A195 PolarHBondContact O-N 2.82Å; A195-G197 VanDerWaalsContact C-N 3.29Å; A195-G197 PolarHBondContact O-N 3.48Å
196I97.2Very high97.6Very high102 Ų10261.6 Ų61.652%0.52334%0.339SS..Hα-helixtrans-82.5-3.2179.470.5-174.1000113.6T192 S193 V194 M198T192-I196 WeakPolarHBondContact O-CG1 3.34Å; T192-I196 PolarHBondContact O-N 2.78Å; T192-I196 VanDerWaalsContact O-N 3.09Å; S193-I196 WeakPolarHBondContact O-CG1 3.47Å; V194-I196 PolarHBondContact O-N 2.56Å; I196-M198 HydrophobicContact CD1-CB 4.11Å; I196-M198 HydrophobicContact CD1-CG 3.97Å; I196-M198 HydrophobicContact CD1-SD 3.46Å; I196-M198 WeakPolarHBondContact CD1-SD 3.2Å; I196-M198 HydrophobicContact CG1-CB 3.87Å; I196-M198 HydrophobicContact CG1-CG 3.79Å; I196-M198 HydrophobicContact CG1-SD 3.95Å
197G96.9Very high97.4Very high48 Ų4863.4 Ų63.450%0.49535%0.349SS..THydrogen-bonded Turntrans70.131.6178.700000114.2S193 V194 A195S193-G197 PolarHBondContact O-N 2.78Å; V194-G197 PolarHBondContact O-N 3.14Å; V194-G197 VanDerWaalsContact O-N 3.1Å; A195-G197 VanDerWaalsContact C-N 3.29Å; A195-G197 PolarHBondContact O-N 3.48Å
198M97.5Very high97.2Very high115 Ų11570.5 Ų70.557%0.56739%0.387SS*.  trans-108135.5179.1-72.4-179.662.600111.4S193 I196S193-M198 CarbonylContact C-O 3.56Å; S193-M198 WeakPolarHBondContact CB-O 3.16Å; S193-M198 PolarHBondContact O-N 3.19Å; I196-M198 HydrophobicContact CD1-CB 4.11Å; I196-M198 HydrophobicContact CD1-CG 3.97Å; I196-M198 HydrophobicContact CD1-SD 3.46Å; I196-M198 WeakPolarHBondContact CD1-SD 3.2Å; I196-M198 HydrophobicContact CG1-CB 3.87Å; I196-M198 HydrophobicContact CG1-CG 3.79Å; I196-M198 HydrophobicContact CG1-SD 3.95Å
199T97.2Very high97Very high145 Ų14575.4 Ų75.489%0.8941%0.407SS*.  trans-82.5128167.3-55.20000109.1
200I97.7Very high96.8Very high51 Ų5174 Ų7426%0.26239%0.394SS..  trans-113.2153.4175.657.9172.2000111.4T189 Y190 L219T189-I200 HydrophobicContact CG2-CD1 4.12Å; Y190-I200 HydrophobicContact CD2-CD1 4.49Å; I200-L219 HydrophobicContact CD1-CD2 3.46Å; I200-L219 VanDerWaalsContact CD1-CD2 3.46Å; I200-L219 HydrophobicContact CG1-CD2 3.83Å
201P97.5Very high96.6Very high101 Ų10180.1 Ų80.166%0.65642%0.424SS*.  trans-62.4150.5176.7-21.433.7000112.4
202N97.8Very high96.3Very high59 Ų5984.7 Ų84.732%0.31644%0.442SS..SBendtrans-79.4-23.6171.7-172.542.7000112.4K218 L219 H220N202-K218 CarbonylContact O-C 3.53Å; N202-K218 VanDerWaalsContact O-CA 3.28Å; N202-K218 WeakPolarHBondContact O-CA 3.14Å; N202-L219 PolarHBondContact O-N 3Å; N202-L219 PolarHBondContact OD1-N 2.87Å; N202-H220 WeakPolarHBondContact OD1-CB 3.45Å; N202-H220 PolarHBondContact OD1-CD2 2.87Å; N202-H220 PolarHBondContact OD1-N 2.82Å
203D97.6Very high96.1Very high103 Ų10384.3 Ų84.355%0.55144%0.436SS*.BIsolated β-bridgetrans-73.7126.4173-70.3-74.6000110.1K218D203-K218 IonicContact OD1-NZ 2.56Å; D203-K218 PolarHBondContact OD1-NZ 2.85Å; D203-K218 IonicContact OD2-NZ 3.8Å
204L96.2Very high95.8Very high33 Ų3384.9 Ų84.917%0.17344%0.443CS..PPolyproline II helixtrans-72.4135.8178.8-63.9179.1000110.7F210 Y213 F217 L219L204-F210 HydrophobicContact CB-CE2 4.12Å; L204-Y213 VanDerWaalsContact CD1-CB 3.4Å; L204-Y213 HydrophobicContact CD1-CD1 3.65Å; L204-Y213 HydrophobicContact CD1-CD2 4.17Å; L204-Y213 HydrophobicContact CD1-CE1 4.47Å; L204-Y213 HydrophobicContact CD1-CG 3.47Å; L204-Y213 VanDerWaalsContact CD1-CG 3.47Å; L204-F217 WeakPolarHBondContact CB-O 3.48Å; L204-F217 WeakPolarHBondContact CG-O 3.26Å; L204-F217 PolarHBondContact N-O 2.71Å; L204-F217 VanDerWaalsContact N-O 3.09Å; L204-L219 HydrophobicContact CD2-CB 4.05Å; L204-L219 HydrophobicContact CD2-CD1 4.37Å
205P95.7Very high95.5Very high99 Ų9990 Ų9064%0.64348%0.477SS*.PPolyproline II helixtrans-70.3153.317031.2-34.3000110.5N207 F210P205-N207 PolarHBondContact O-N 2.91Å; P205-N207 PolarHBondContact O-ND2 2.84Å; P205-F210 WeakPolarHBondContact O-CD2 3.26Å
206Y94.9Very high95.2Very high192 Ų19293 Ų9375%0.75349%0.492SS*.PPolyproline II helixtrans-58.7136.9171.3-176.5-97.5000110.6F210Y206-F210 HydrophobicContact CD2-CB 4.19Å; Y206-F210 HydrophobicContact CD2-CD1 4.31Å; Y206-F210 HydrophobicContact CD2-CG 4.17Å; Y206-F210 HydrophobicContact CE2-CB 4.41Å
207N92.7Very high95.1Very high47 Ų4791.4 Ų91.425%0.25148%0.481SS..  trans-155.2170177.964.785.2000109.5P205 Y209 F210P205-N207 PolarHBondContact O-N 2.91Å; P205-N207 PolarHBondContact O-ND2 2.84Å; N207-Y209 PolarHBondContact O-N 3.26Å; N207-Y209 VanDerWaalsContact O-N 3.12Å; N207-Y209 VanDerWaalsContact OD1-CA 3.27Å; N207-Y209 WeakPolarHBondContact OD1-CA 3.17Å; N207-Y209 WeakPolarHBondContact OD1-CB 3.31Å; N207-Y209 PolarHBondContact OD1-N 2.6Å; N207-F210 WeakPolarHBondContact O-CB 3.46Å; N207-F210 PolarHBondContact O-N 3.4Å; N207-F210 PolarHBondContact OD1-N 2.96Å; N207-F210 VanDerWaalsContact OD1-N 3.12Å
208D95Very high95.1Very high149 Ų14992.2 Ų92.280%0.79747%0.471SS*.THydrogen-bonded Turntrans-63.7-19.8-176.6-60.8-26.7000113.5
209Y93.8Very high95.1Very high147 Ų14786.9 Ų86.958%0.57645%0.445SS*.THydrogen-bonded Turntrans-106.817.3177.8-52.2-82.7000112.4N207 E211 Y212 Y213N207-Y209 PolarHBondContact O-N 3.26Å; N207-Y209 VanDerWaalsContact O-N 3.12Å; N207-Y209 VanDerWaalsContact OD1-CA 3.27Å; N207-Y209 WeakPolarHBondContact OD1-CA 3.17Å; N207-Y209 WeakPolarHBondContact OD1-CB 3.31Å; N207-Y209 PolarHBondContact OD1-N 2.6Å; Y209-E211 PolarHBondContact O-N 2.94Å; Y209-E211 VanDerWaalsContact O-N 3.12Å; Y209-Y212 HydrophobicContact CD1-CD2 4.28Å; Y209-Y212 AromaticContact CD1-CE2 3.96Å; Y209-Y212 HydrophobicContact CD1-CE2 3.96Å; Y209-Y212 WeakPolarHBondContact O-CB 3.3Å; Y209-Y212 VanDerWaalsContact O-CD2 3.31Å; Y209-Y212 WeakPolarHBondContact O-CD2 3.43Å; Y209-Y212 PolarHBondContact O-N 3.19Å; Y209-Y212 VanDerWaalsContact O-N 3.11Å; Y209-Y213 WeakPolarHBondContact O-CD2 3.43Å; Y209-Y213 VanDerWaalsContact O-CE2 3.26Å; Y209-Y213 WeakPolarHBondContact O-CE2 2.73Å
210F93.5Very high95.1Very high49 Ų4981.4 Ų81.422%0.21541%0.41CS..G310 helixtrans-56.3-35.7-171.4-172.8-105.8000113.2L204 P205 Y206 N207 Y212 Y213 F217L204-F210 HydrophobicContact CB-CE2 4.12Å; P205-F210 WeakPolarHBondContact O-CD2 3.26Å; Y206-F210 HydrophobicContact CD2-CB 4.19Å; Y206-F210 HydrophobicContact CD2-CD1 4.31Å; Y206-F210 HydrophobicContact CD2-CG 4.17Å; Y206-F210 HydrophobicContact CE2-CB 4.41Å; N207-F210 WeakPolarHBondContact O-CB 3.46Å; N207-F210 PolarHBondContact O-N 3.4Å; N207-F210 PolarHBondContact OD1-N 2.96Å; N207-F210 VanDerWaalsContact OD1-N 3.12Å; F210-Y212 VanDerWaalsContact C-N 3.31Å; F210-Y212 PolarHBondContact O-N 3.39Å; F210-Y213 PolarHBondContact O-N 3.27Å; F210-F217 AromaticContact CD1-CD1 3.85Å; F210-F217 HydrophobicContact CD1-CD1 3.85Å; F210-F217 AromaticContact CD1-CE1 3.8Å; F210-F217 HydrophobicContact CD1-CE1 3.8Å; F210-F217 HydrophobicContact CD2-CD1 4.4Å; F210-F217 AromaticContact CE1-CD1 3.37Å; F210-F217 HydrophobicContact CE1-CD1 3.37Å; F210-F217 AromaticContact CE1-CE1 3.56Å; F210-F217 HydrophobicContact CE1-CE1 3.56Å; F210-F217 AromaticContact CE1-CG 3.98Å; F210-F217 HydrophobicContact CE1-CG 3.98Å; F210-F217 HydrophobicContact CE1-CZ 4.31Å; F210-F217 HydrophobicContact CE2-CB 4.29Å; F210-F217 AromaticContact CE2-CD1 3.99Å; F210-F217 HydrophobicContact CE2-CD1 3.99Å; F210-F217 HydrophobicContact CE2-CG 4.45Å; F210-F217 HydrophobicContact CG-CD1 4.34Å; F210-F217 HydrophobicContact CZ-CB 3.89Å; F210-F217 AromaticContact CZ-CD1 3.45Å; F210-F217 HydrophobicContact CZ-CD1 3.45Å; F210-F217 VanDerWaalsContact CZ-CD1 3.45Å; F210-F217 HydrophobicContact CZ-CE1 4.15Å; F210-F217 AromaticContact CZ-CG 3.76Å; F210-F217 HydrophobicContact CZ-CG 3.76Å; F210-F217 WeakPolarHBondContact O-CE1 3.45Å
211E94.5Very high95Very high174 Ų17479.9 Ų79.981%0.81340%0.402SS*.G310 helixtrans-66.9-26.8-177.8-62.8-176.3166.500113.7Y209 Y213 G214Y209-E211 PolarHBondContact O-N 2.94Å; Y209-E211 VanDerWaalsContact O-N 3.12Å; E211-Y213 PolarHBondContact O-N 3.29Å; E211-Y213 VanDerWaalsContact O-N 3.16Å; E211-G214 PolarHBondContact O-N 3.34Å; E211-G214 VanDerWaalsContact O-N 3.17Å
212Y93Very high94.8Very high96 Ų9680.5 Ų80.538%0.37640%0.403SS..G310 helixtrans-64.5-21.1177.4-68.2-99.8000112.8R182 Y209 F210 H290R182-Y212 WeakPolarHBondContact CD-O 3.4Å; Y209-Y212 HydrophobicContact CD1-CD2 4.28Å; Y209-Y212 AromaticContact CD1-CE2 3.96Å; Y209-Y212 HydrophobicContact CD1-CE2 3.96Å; Y209-Y212 WeakPolarHBondContact O-CB 3.3Å; Y209-Y212 VanDerWaalsContact O-CD2 3.31Å; Y209-Y212 WeakPolarHBondContact O-CD2 3.43Å; Y209-Y212 PolarHBondContact O-N 3.19Å; Y209-Y212 VanDerWaalsContact O-N 3.11Å; F210-Y212 VanDerWaalsContact C-N 3.31Å; F210-Y212 PolarHBondContact O-N 3.39Å; Y212-H290 AromaticContact CE1-CE1 3.4Å; Y212-H290 VanDerWaalsContact CE1-CE1 3.4Å; Y212-H290 WeakPolarHBondContact CE1-CE1 3.33Å; Y212-H290 AromaticContact CE1-NE2 3.32Å; Y212-H290 VanDerWaalsContact CE1-NE2 3.32Å; Y212-H290 WeakPolarHBondContact CE1-NE2 3.39Å; Y212-H290 AromaticContact CZ-CE1 3.5Å; Y212-H290 AromaticContact CZ-NE2 3.54Å; Y212-H290 PolarHBondContact OH-CE1 2.91Å; Y212-H290 PolarHBondContact OH-NE2 3.47Å; Y212-H290 VanDerWaalsContact OH-NE2 3.08Å
213Y94.7Very high94.4Very high34 Ų3481.3 Ų81.313%0.13341%0.412CS..G310 helixtrans-93.66.1-178-57-84.8000113.2R182 A185 R186 L204 Y209 F210 E211 D216 F217R182-Y213 HydrophobicContact CB-CD1 4.18Å; R182-Y213 HydrophobicContact CB-CE1 4.06Å; R182-Y213 WeakPolarHBondContact O-CE1 3.08Å; A185-Y213 HydrophobicContact CB-CE1 4.4Å; A185-Y213 WeakPolarHBondContact CB-OH 3.39Å; R186-Y213 HydrophobicContact CG-CD1 4.27Å; R186-Y213 HydrophobicContact CG-CE1 4.19Å; R186-Y213 PolarHBondContact NH2-O 3.37Å; R186-Y213 VanDerWaalsContact NH2-O 3.11Å; L204-Y213 VanDerWaalsContact CD1-CB 3.4Å; L204-Y213 HydrophobicContact CD1-CD1 3.65Å; L204-Y213 HydrophobicContact CD1-CD2 4.17Å; L204-Y213 HydrophobicContact CD1-CE1 4.47Å; L204-Y213 HydrophobicContact CD1-CG 3.47Å; L204-Y213 VanDerWaalsContact CD1-CG 3.47Å; Y209-Y213 WeakPolarHBondContact O-CD2 3.43Å; Y209-Y213 VanDerWaalsContact O-CE2 3.26Å; Y209-Y213 WeakPolarHBondContact O-CE2 2.73Å; F210-Y213 PolarHBondContact O-N 3.27Å; E211-Y213 PolarHBondContact O-N 3.29Å; E211-Y213 VanDerWaalsContact O-N 3.16Å; Y213-D216 VanDerWaalsContact O-OD1 3.06Å; Y213-F217 PolarHBondContact O-N 3.01Å; Y213-F217 VanDerWaalsContact O-N 3.09Å
214G91.6Very high94.1Very high17 Ų1778.4 Ų78.418%0.17540%0.4CS..THydrogen-bonded Turntrans-64.8160.1173.100000113.2E211E211-G214 PolarHBondContact O-N 3.34Å; E211-G214 VanDerWaalsContact O-N 3.17Å
215P93Very high93.9Very high125 Ų12584.5 Ų84.581%0.81243%0.433SS*.THydrogen-bonded Turncis-89.4-7.10.535.9-36000114.1F217P215-F217 WeakPolarHBondContact O-CD2 3.47Å; P215-F217 WeakPolarHBondContact O-CE2 3.37Å
216D91.8Very high93.8Very high66 Ų6683.7 Ų83.735%0.35342%0.423SS..THydrogen-bonded Turntrans-91.4-27-168.862.1-4.9000113.6R186 Y213 K218R186-D216 IonicContact NH2-OD1 3.47Å; R186-D216 PolarHBondContact NH2-OD1 3.05Å; Y213-D216 VanDerWaalsContact O-OD1 3.06Å; D216-K218 HydrophobicContact CB-CG 4.21Å; D216-K218 WeakPolarHBondContact O-CG 3.4Å; D216-K218 PolarHBondContact O-N 3.05Å
217F95.2Very high93.9Very high69 Ų6979.9 Ų79.930%0.30342%0.42SS..  trans52.236.7-179-51.3-81000112.4L204 F210 Y213 P215L204-F217 WeakPolarHBondContact CB-O 3.48Å; L204-F217 WeakPolarHBondContact CG-O 3.26Å; L204-F217 PolarHBondContact N-O 2.71Å; L204-F217 VanDerWaalsContact N-O 3.09Å; F210-F217 AromaticContact CD1-CD1 3.85Å; F210-F217 HydrophobicContact CD1-CD1 3.85Å; F210-F217 AromaticContact CD1-CE1 3.8Å; F210-F217 HydrophobicContact CD1-CE1 3.8Å; F210-F217 HydrophobicContact CD2-CD1 4.4Å; F210-F217 AromaticContact CE1-CD1 3.37Å; F210-F217 HydrophobicContact CE1-CD1 3.37Å; F210-F217 AromaticContact CE1-CE1 3.56Å; F210-F217 HydrophobicContact CE1-CE1 3.56Å; F210-F217 AromaticContact CE1-CG 3.98Å; F210-F217 HydrophobicContact CE1-CG 3.98Å; F210-F217 HydrophobicContact CE1-CZ 4.31Å; F210-F217 HydrophobicContact CE2-CB 4.29Å; F210-F217 AromaticContact CE2-CD1 3.99Å; F210-F217 HydrophobicContact CE2-CD1 3.99Å; F210-F217 HydrophobicContact CE2-CG 4.45Å; F210-F217 HydrophobicContact CG-CD1 4.34Å; F210-F217 HydrophobicContact CZ-CB 3.89Å; F210-F217 AromaticContact CZ-CD1 3.45Å; F210-F217 HydrophobicContact CZ-CD1 3.45Å; F210-F217 VanDerWaalsContact CZ-CD1 3.45Å; F210-F217 HydrophobicContact CZ-CE1 4.15Å; F210-F217 AromaticContact CZ-CG 3.76Å; F210-F217 HydrophobicContact CZ-CG 3.76Å; F210-F217 WeakPolarHBondContact O-CE1 3.45Å; Y213-F217 PolarHBondContact O-N 3.01Å; Y213-F217 VanDerWaalsContact O-N 3.09Å; P215-F217 WeakPolarHBondContact O-CD2 3.47Å; P215-F217 WeakPolarHBondContact O-CE2 3.37Å
218K97.2Very high94.1Very high65 Ų6579.9 Ų79.928%0.28342%0.42SS..BIsolated β-bridgetrans-106.7150.9178.5-59-50.9179.41760112R186 N202 D203 D216R186-K218 PolarHBondContact NE-O 2.68Å; R186-K218 PolarHBondContact NH2-O 2.84Å; N202-K218 CarbonylContact O-C 3.53Å; N202-K218 VanDerWaalsContact O-CA 3.28Å; N202-K218 WeakPolarHBondContact O-CA 3.14Å; D203-K218 IonicContact OD1-NZ 2.56Å; D203-K218 PolarHBondContact OD1-NZ 2.85Å; D203-K218 IonicContact OD2-NZ 3.8Å; D216-K218 HydrophobicContact CB-CG 4.21Å; D216-K218 WeakPolarHBondContact O-CG 3.4Å; D216-K218 PolarHBondContact O-N 3.05Å
219L97.4Very high94.3Very high4 Ų477.3 Ų77.32%0.02140%0.403CS..SBendtrans-68.7-44.9170.1179.567.6000111.2R186 T189 Y190 I200 N202 L204R186-L219 HydrophobicContact CB-CD1 4.21Å; R186-L219 WeakPolarHBondContact CB-O 3.46Å; R186-L219 WeakPolarHBondContact CD-O 3.35Å; R186-L219 HydrophobicContact CG-CD1 4.43Å; R186-L219 WeakPolarHBondContact CG-O 3.49Å; R186-L219 WeakPolarHBondContact O-CD1 3.43Å; T189-L219 HydrophobicContact CG2-CD1 4.42Å; Y190-L219 HydrophobicContact CD2-CD2 3.94Å; Y190-L219 HydrophobicContact CG-CD2 4.42Å; I200-L219 HydrophobicContact CD1-CD2 3.46Å; I200-L219 VanDerWaalsContact CD1-CD2 3.46Å; I200-L219 HydrophobicContact CG1-CD2 3.83Å; N202-L219 PolarHBondContact O-N 3Å; N202-L219 PolarHBondContact OD1-N 2.87Å; L204-L219 HydrophobicContact CD2-CB 4.05Å; L204-L219 HydrophobicContact CD2-CD1 4.37Å
220H97.4Very high94.5Very high30 Ų3070.6 Ų70.614%0.13938%0.377CS..SBendtrans-92.3123.1-177.1-60.3-56.5000111.9K155 Y190 N202K155-H220 WeakPolarHBondContact CE-CD2 3.38Å; K155-H220 WeakPolarHBondContact CE-NE2 3.37Å; K155-H220 HydrophobicContact CG-CB 4.44Å; K155-H220 WeakPolarHBondContact CG-ND1 3.23Å; Y190-H220 AromaticContact CD2-CE1 3.57Å; Y190-H220 AromaticContact CE2-CE1 3.47Å; Y190-H220 VanDerWaalsContact CE2-CE1 3.47Å; Y190-H220 WeakPolarHBondContact CE2-CE1 3.5Å; Y190-H220 AromaticContact CG-CE1 3.95Å; Y190-H220 AromaticContact CZ-CE1 3.77Å; N202-H220 WeakPolarHBondContact OD1-CB 3.45Å; N202-H220 PolarHBondContact OD1-CD2 2.87Å; N202-H220 PolarHBondContact OD1-N 2.82Å
221I94.6Very high94.8Very high19 Ų1971.1 Ų71.110%0.09739%0.386CS..PPolyproline II helixtrans-79.2152.9174.864.8-174.2000111.9L142 T143 V154L142-I221 HydrophobicContact CB-CD1 4.23Å; L142-I221 HydrophobicContact CD1-CD1 4.44Å; T143-I221 HydrophobicContact CG2-CD1 3.57Å; T143-I221 HydrophobicContact CG2-CG1 3.87Å; V154-I221 HydrophobicContact CG2-CD1 4.16Å; V154-I221 HydrophobicContact CG2-CG1 4.08Å
222T92.7Very high94.9Very high113 Ų11367.6 Ų67.669%0.69338%0.381SS*.PPolyproline II helixtrans-88.1137.5177.7-56.20000110T143T143-T222 WeakPolarHBondContact CG2-O 3.38Å
223P90Very high95.2Very high76 Ų7669.7 Ų69.749%0.49439%0.394SS..PPolyproline II helixtrans-55.1141.9172.1-18.425.8000112.1T153T153-P223 HydrophobicContact CG2-CB 4.3Å; T153-P223 HydrophobicContact CG2-CG 3.52Å
224S91.2Very high95.4Very high43 Ų4370.2 Ų70.230%0.30140%0.396SS..PPolyproline II helixtrans-79168.2169.669.20000111.6T143 N151 L226T143-S224 WeakPolarHBondContact OG1-CB 3.48Å; T143-S224 PolarHBondContact OG1-N 3.39Å; T143-S224 VanDerWaalsContact OG1-N 3.16Å; T143-S224 PolarHBondContact OG1-OG 3.09Å; T143-S224 VanDerWaalsContact OG1-OG 3.09Å; N151-S224 PolarHBondContact ND2-O 3.41Å; N151-S224 VanDerWaalsContact ND2-O 3.13Å; N151-S224 PolarHBondContact OD1-N 3.12Å; N151-S224 PolarHBondContact OD1-OG 2.89Å; S224-L226 PolarHBondContact O-N 3.45Å; S224-L226 WeakPolarHBondContact OG-CD1 3.42Å; S224-L226 WeakPolarHBondContact OG-CG 3.46Å
225N92.3Very high95.7Very high160 Ų16069.9 Ų69.986%0.85639%0.39SS*.  trans-81.218.2175.466.7-21.2000113.6T227N225-T227 PolarHBondContact O-N 3.21Å
226L93.4Very high96Very high83 Ų8370.9 Ų70.944%0.43538%0.378SS..  trans-56.8129.8176.5-74.2173000110.8N151 S224 N228N151-L226 HydrophobicContact CB-CD1 4.48Å; S224-L226 PolarHBondContact O-N 3.45Å; S224-L226 WeakPolarHBondContact OG-CD1 3.42Å; S224-L226 WeakPolarHBondContact OG-CG 3.46Å; L226-N228 PolarHBondContact O-N 2.98Å
227T96.9Very high96.3Very high112 Ų11275.1 Ų75.169%0.68739%0.393SS*.  trans-65.2122.3175.9-600000109.8N225 Q229N225-T227 PolarHBondContact O-N 3.21Å; T227-Q229 PolarHBondContact O-N 3.36Å; T227-Q229 VanDerWaalsContact O-N 3.16Å
228N98.1Very high96.5Very high47 Ų4772 Ų7225%0.25138%0.38SS..  trans-73.2106.8174.4-171.8-10.8000110.6G107 T109 S112 L226 N230G107-N228 VanDerWaalsContact O-CA 3.29Å; G107-N228 WeakPolarHBondContact O-CA 3.22Å; G107-N228 WeakPolarHBondContact O-CB 3.49Å; G107-N228 PolarHBondContact O-OD1 3.17Å; T109-N228 HydrophobicContact CG2-CB 4.33Å; T109-N228 PolarHBondContact OG1-ND2 2.99Å; S112-N228 PolarHBondContact OG-ND2 2.96Å; L226-N228 PolarHBondContact O-N 2.98Å; N228-N230 PolarHBondContact O-N 3.02Å; N228-N230 WeakPolarHBondContact OD1-CA 3.46Å; N228-N230 WeakPolarHBondContact OD1-CB 3.4Å; N228-N230 PolarHBondContact OD1-N 3.12Å; N228-N230 PolarHBondContact OD1-ND2 2.91Å
229Q98.3Very high96.5Very high95 Ų9570.5 Ų70.544%0.44437%0.374SS..  trans-81.80.6179.6-61.6-171.938.400113.3R105 D106 T227 S231R105-Q229 HydrophobicContact CB-CB 3.79Å; R105-Q229 VanDerWaalsContact CD-O 3.31Å; R105-Q229 WeakPolarHBondContact CD-O 3.29Å; D106-Q229 HydrophobicContact CB-CG 4.31Å; D106-Q229 PolarHBondContact O-N 2.6Å; D106-Q229 PolarHBondContact OD2-NE2 3.4Å; T227-Q229 PolarHBondContact O-N 3.36Å; T227-Q229 VanDerWaalsContact O-N 3.16Å; Q229-S231 PolarHBondContact O-N 3.02Å
230N98.5Very high96.6Very high5 Ų573.9 Ų73.93%0.02739%0.392CS..  trans-93.177.4179.9-56-88.5000110.6R105 D106 I108 N228 Y234 L235R105-N230 PolarHBondContact N-OD1 3.3Å; R105-N230 PolarHBondContact O-ND2 3.48Å; D106-N230 PolarHBondContact O-ND2 2.97Å; I108-N230 WeakPolarHBondContact CB-ND2 3.32Å; I108-N230 HydrophobicContact CD1-CB 3.54Å; I108-N230 PolarHBondContact N-ND2 2.76Å; N228-N230 PolarHBondContact O-N 3.02Å; N228-N230 WeakPolarHBondContact OD1-CA 3.46Å; N228-N230 WeakPolarHBondContact OD1-CB 3.4Å; N228-N230 PolarHBondContact OD1-N 3.12Å; N228-N230 PolarHBondContact OD1-ND2 2.91Å; N230-Y234 HydrophobicContact CB-CD1 4.5Å; N230-L235 HydrophobicContact CB-CD1 4.05Å; N230-L235 HydrophobicContact CB-CD2 3.85Å; N230-L235 HydrophobicContact CB-CG 3.96Å
231S98.2Very high96.6Very high60 Ų6076.4 Ų76.442%0.4240%0.402SS..  trans-58.8148.9177.574.40000111.4Q229 E233 Y234 L235Q229-S231 PolarHBondContact O-N 3.02Å; S231-E233 PolarHBondContact O-N 3.12Å; S231-E233 VanDerWaalsContact O-N 3.12Å; S231-Y234 WeakPolarHBondContact O-CB 3.43Å; S231-Y234 PolarHBondContact O-N 3.22Å; S231-Y234 WeakPolarHBondContact OG-CB 3.35Å; S231-Y234 PolarHBondContact OG-N 3.34Å; S231-Y234 VanDerWaalsContact OG-N 3.16Å; S231-L235 PolarHBondContact O-N 2.86Å
232S98.1Very high96.8Very high101 Ų10175.6 Ų75.671%0.70640%0.398SS*.Hα-helixtrans-56.1-31.6176.8-51.90000112.6R236S232-R236 WeakPolarHBondContact O-CB 3.13Å; S232-R236 PolarHBondContact O-N 3.14Å
233E98.4Very high97.1Very high140 Ų14073.1 Ų73.165%0.65438%0.379SS*.Hα-helixtrans-68.2-44.8174.9-174.9179.3-17700112.2S231 R236 K237S231-E233 PolarHBondContact O-N 3.12Å; S231-E233 VanDerWaalsContact O-N 3.12Å; E233-R236 PolarHBondContact O-N 3.11Å; E233-K237 WeakPolarHBondContact O-CB 3.33Å; E233-K237 PolarHBondContact O-N 3.29Å
234Y98.6Very high97.5Very high44 Ų4475 Ų7517%0.17338%0.381CS..Hα-helixtrans-61.4-51.2176.7171.1-107.6000111.3P103 R105 N230 S231 R236 K237 I238P103-Y234 PolarHBondContact O-OH 3.36Å; R105-Y234 HydrophobicContact CG-CE1 3.87Å; N230-Y234 HydrophobicContact CB-CD1 4.5Å; S231-Y234 WeakPolarHBondContact O-CB 3.43Å; S231-Y234 PolarHBondContact O-N 3.22Å; S231-Y234 WeakPolarHBondContact OG-CB 3.35Å; S231-Y234 PolarHBondContact OG-N 3.34Å; S231-Y234 VanDerWaalsContact OG-N 3.16Å; Y234-R236 VanDerWaalsContact C-N 3.34Å; Y234-R236 PolarHBondContact O-N 3.12Å; Y234-K237 WeakPolarHBondContact O-CB 3.5Å; Y234-K237 PolarHBondContact O-N 2.81Å; Y234-K237 VanDerWaalsContact O-N 3.17Å; Y234-I238 HydrophobicContact CD1-CD1 4.16Å; Y234-I238 HydrophobicContact CD2-CD1 4.32Å; Y234-I238 HydrophobicContact CE1-CD1 3.57Å; Y234-I238 HydrophobicContact CE2-CD1 3.73Å; Y234-I238 HydrophobicContact CE2-CG1 4.41Å; Y234-I238 PolarHBondContact O-N 2.97Å; Y234-I238 VanDerWaalsContact O-N 3.14Å
235L98.8Very high97.8Very high10 Ų1073.4 Ų73.45%0.05237%0.369CS..Hα-helixtrans-58.9-45.9178.2-66.9-179.6000111.3F102 L104 I108 I116 N230 S231 K237 I238 M239F102-L235 HydrophobicContact CE1-CD2 3.75Å; F102-L235 HydrophobicContact CZ-CD2 4.11Å; L104-L235 HydrophobicContact CD2-CD2 4.29Å; I108-L235 HydrophobicContact CD1-CD1 4.06Å; I108-L235 HydrophobicContact CD1-CD2 4.36Å; I116-L235 HydrophobicContact CD1-CD2 4.2Å; I116-L235 HydrophobicContact CG2-CB 4.04Å; I116-L235 HydrophobicContact CG2-CD1 4.06Å; I116-L235 HydrophobicContact CG2-CD2 4.17Å; I116-L235 HydrophobicContact CG2-CG 4.32Å; N230-L235 HydrophobicContact CB-CD1 4.05Å; N230-L235 HydrophobicContact CB-CD2 3.85Å; N230-L235 HydrophobicContact CB-CG 3.96Å; S231-L235 PolarHBondContact O-N 2.86Å; L235-K237 VanDerWaalsContact C-N 3.31Å; L235-K237 PolarHBondContact O-N 3Å; L235-I238 PolarHBondContact O-N 2.94Å; L235-M239 WeakPolarHBondContact O-CG 3.46Å; L235-M239 PolarHBondContact O-N 3.44Å
236R98.4Very high98.1Very high146 Ų14666 Ų6655%0.55133%0.329SS*.Hα-helixtrans-61.3-38.1177.9-174.81746683.60.8112.5S232 E233 Y234 M239 L240S232-R236 WeakPolarHBondContact O-CB 3.13Å; S232-R236 PolarHBondContact O-N 3.14Å; E233-R236 PolarHBondContact O-N 3.11Å; Y234-R236 VanDerWaalsContact C-N 3.34Å; Y234-R236 PolarHBondContact O-N 3.12Å; R236-M239 PolarHBondContact O-N 3.21Å; R236-L240 HydrophobicContact CG-CD1 4.29Å; R236-L240 HydrophobicContact CG-CG 4.49Å; R236-L240 VanDerWaalsContact O-CG 3.3Å; R236-L240 WeakPolarHBondContact O-CG 3.32Å; R236-L240 PolarHBondContact O-N 3.42Å
237K98.6Very high98.2Very high155 Ų15567 Ų6767%0.67434%0.335SS*.Hα-helixtrans-63-43.2176.8-178-179.1176.5-1780111.5E233 Y234 L235 K241E233-K237 WeakPolarHBondContact O-CB 3.33Å; E233-K237 PolarHBondContact O-N 3.29Å; Y234-K237 WeakPolarHBondContact O-CB 3.5Å; Y234-K237 PolarHBondContact O-N 2.81Å; Y234-K237 VanDerWaalsContact O-N 3.17Å; L235-K237 VanDerWaalsContact C-N 3.31Å; L235-K237 PolarHBondContact O-N 3Å; K237-K241 PolarHBondContact O-N 2.8Å
238I98.7Very high98.2Very high5 Ų564.1 Ų64.13%0.02632%0.323CS..Hα-helixtrans-64.6-50175.9-65.5171.9000110L87 F102 P103 Y234 L235 L240 K241 L242L87-I238 HydrophobicContact CD1-CG2 4.08Å; L87-I238 HydrophobicContact CD2-CG1 4.31Å; F102-I238 HydrophobicContact CD1-CD1 4.29Å; F102-I238 HydrophobicContact CD1-CG2 3.75Å; F102-I238 HydrophobicContact CD2-CG2 3.97Å; F102-I238 HydrophobicContact CE1-CB 3.93Å; F102-I238 HydrophobicContact CE1-CD1 3.88Å; F102-I238 HydrophobicContact CE1-CG2 3.59Å; F102-I238 HydrophobicContact CE2-CB 4.48Å; F102-I238 HydrophobicContact CE2-CG2 3.82Å; F102-I238 HydrophobicContact CG-CG2 3.92Å; F102-I238 HydrophobicContact CZ-CB 3.89Å; F102-I238 HydrophobicContact CZ-CG2 3.62Å; P103-I238 HydrophobicContact CG-CD1 3.99Å; P103-I238 WeakPolarHBondContact O-CD1 3.5Å; Y234-I238 HydrophobicContact CD1-CD1 4.16Å; Y234-I238 HydrophobicContact CD2-CD1 4.32Å; Y234-I238 HydrophobicContact CE1-CD1 3.57Å; Y234-I238 HydrophobicContact CE2-CD1 3.73Å; Y234-I238 HydrophobicContact CE2-CG1 4.41Å; Y234-I238 PolarHBondContact O-N 2.97Å; Y234-I238 VanDerWaalsContact O-N 3.14Å; L235-I238 PolarHBondContact O-N 2.94Å; I238-L240 VanDerWaalsContact C-N 3.34Å; I238-L240 PolarHBondContact O-N 3.11Å; I238-K241 PolarHBondContact O-N 3.2Å; I238-L242 HydrophobicContact CG2-CD1 3.8Å; I238-L242 HydrophobicContact CG2-CG 4.05Å; I238-L242 WeakPolarHBondContact O-CG 3.49Å; I238-L242 PolarHBondContact O-N 3.12Å
239M98.6Very high97.9Very high32 Ų3262.5 Ų62.516%0.15831%0.314CS..Hα-helixtrans-53.1-50.1179-72.6-1797800111.8F102 I116 P119 I120 L235 R236 K241 L242 E243F102-M239 HydrophobicContact CE2-CG 3.82Å; F102-M239 HydrophobicContact CZ-CG 4Å; I116-M239 HydrophobicContact CB-SD 4.5Å; I116-M239 HydrophobicContact CG2-CG 4.24Å; I116-M239 HydrophobicContact CG2-SD 3.87Å; P119-M239 HydrophobicContact CB-CE 3.83Å; P119-M239 HydrophobicContact CG-CE 4.02Å; I120-M239 HydrophobicContact CD1-CG 4.46Å; L235-M239 WeakPolarHBondContact O-CG 3.46Å; L235-M239 PolarHBondContact O-N 3.44Å; R236-M239 PolarHBondContact O-N 3.21Å; M239-K241 VanDerWaalsContact C-N 3.26Å; M239-K241 PolarHBondContact O-N 3.19Å; M239-L242 PolarHBondContact O-N 3.3Å; M239-E243 WeakPolarHBondContact O-CB 3.35Å; M239-E243 VanDerWaalsContact O-CG 3.25Å; M239-E243 WeakPolarHBondContact O-CG 3.4Å; M239-E243 PolarHBondContact O-N 2.87Å
240L98.5Very high97.4Very high76 Ų7661.9 Ų61.940%0.39832%0.318SS..Hα-helixtrans-58.4-38.9178.9-73.9172000112.4R236 I238 Q244R236-L240 HydrophobicContact CG-CD1 4.29Å; R236-L240 HydrophobicContact CG-CG 4.49Å; R236-L240 VanDerWaalsContact O-CG 3.3Å; R236-L240 WeakPolarHBondContact O-CG 3.32Å; R236-L240 PolarHBondContact O-N 3.42Å; I238-L240 VanDerWaalsContact C-N 3.34Å; I238-L240 PolarHBondContact O-N 3.11Å; L240-Q244 WeakPolarHBondContact O-CG 3.36Å; L240-Q244 PolarHBondContact O-N 3.21Å
241K98.6Very high96.7Very high82 Ų8265.4 Ų65.436%0.35735%0.349SS..Hα-helixtrans-71.5-42.6179.1-18053.9179.5150.10111.8L87 K237 I238 M239 E243 Q244 N245L87-K241 HydrophobicContact CD1-CB 4.28Å; L87-K241 HydrophobicContact CD1-CG 3.96Å; L87-K241 HydrophobicContact CD2-CB 4Å; L87-K241 HydrophobicContact CD2-CG 3.82Å; L87-K241 HydrophobicContact CG-CB 4.43Å; L87-K241 HydrophobicContact CG-CG 3.87Å; K237-K241 PolarHBondContact O-N 2.8Å; I238-K241 PolarHBondContact O-N 3.2Å; M239-K241 VanDerWaalsContact C-N 3.26Å; M239-K241 PolarHBondContact O-N 3.19Å; K241-E243 VanDerWaalsContact C-N 3.32Å; K241-Q244 PolarHBondContact O-N 3.34Å; K241-N245 WeakPolarHBondContact CE-OD1 3.49Å; K241-N245 PolarHBondContact NZ-OD1 3.48Å; K241-N245 VanDerWaalsContact O-CG 3.28Å; K241-N245 PolarHBondContact O-N 3.47Å; K241-N245 PolarHBondContact O-OD1 2.69Å
242L98.6Very high95.9Very high2 Ų264 Ų641%0.0134%0.34CS..Hα-helixtrans-64.4-39.2175.2-68-176.6000111.4L87 V100 F102 I120 I238 M239 Q244 N245 L246L87-L242 HydrophobicContact CD1-CD2 3.44Å; L87-L242 VanDerWaalsContact CD1-CD2 3.44Å; L87-L242 HydrophobicContact CD1-CG 3.83Å; V100-L242 HydrophobicContact CG1-CD1 4.29Å; V100-L242 HydrophobicContact CG1-CD2 3.92Å; F102-L242 HydrophobicContact CB-CD1 4.11Å; F102-L242 HydrophobicContact CD2-CD1 3.43Å; F102-L242 VanDerWaalsContact CD2-CD1 3.43Å; F102-L242 HydrophobicContact CE2-CD1 4.06Å; F102-L242 HydrophobicContact CG-CD1 4.01Å; I120-L242 HydrophobicContact CD1-CB 3.91Å; I120-L242 HydrophobicContact CD1-CD1 4.26Å; I120-L242 HydrophobicContact CG2-CD1 4.47Å; I238-L242 HydrophobicContact CG2-CD1 3.8Å; I238-L242 HydrophobicContact CG2-CG 4.05Å; I238-L242 WeakPolarHBondContact O-CG 3.49Å; I238-L242 PolarHBondContact O-N 3.12Å; M239-L242 PolarHBondContact O-N 3.3Å; L242-Q244 PolarHBondContact O-N 2.81Å; L242-N245 PolarHBondContact O-N 3.14Å; L242-L246 WeakPolarHBondContact O-CB 3.18Å; L242-L246 WeakPolarHBondContact O-CG 3.47Å; L242-L246 PolarHBondContact O-N 3.2Å
243E98.2Very high94.9Very high62 Ų6260.1 Ų60.129%0.2931%0.313SS..Hα-helixtrans-61.3-45174.8-74.5177.2159.600111.5I120 K123 M239 K241 N245 L246 D247I120-E243 HydrophobicContact CD1-CG 4.42Å; K123-E243 HydrophobicContact CD-CB 4.15Å; K123-E243 HydrophobicContact CD-CG 3.81Å; K123-E243 WeakPolarHBondContact CE-O 3.47Å; M239-E243 WeakPolarHBondContact O-CB 3.35Å; M239-E243 VanDerWaalsContact O-CG 3.25Å; M239-E243 WeakPolarHBondContact O-CG 3.4Å; M239-E243 PolarHBondContact O-N 2.87Å; K241-E243 VanDerWaalsContact C-N 3.32Å; E243-N245 VanDerWaalsContact C-N 3.33Å; E243-N245 PolarHBondContact O-N 2.87Å; E243-L246 PolarHBondContact O-N 3.32Å; E243-D247 WeakPolarHBondContact O-CB 3.44Å; E243-D247 PolarHBondContact O-N 3.43Å; E243-D247 VanDerWaalsContact O-OD2 3.11Å
244Q98.1Very high93.6Very high114 Ų11456.7 Ų56.753%0.53332%0.315SS..Hα-helixtrans-60.8-40.9174.3-73.3168.64.900112.5L240 K241 L242 D247 A248L240-Q244 WeakPolarHBondContact O-CG 3.36Å; L240-Q244 PolarHBondContact O-N 3.21Å; K241-Q244 PolarHBondContact O-N 3.34Å; L242-Q244 PolarHBondContact O-N 2.81Å; Q244-D247 PolarHBondContact O-N 3.09Å; Q244-A248 WeakPolarHBondContact O-CB 3.2Å; Q244-A248 PolarHBondContact O-N 3.1Å
245N98.2Very high92.5Very high11 Ų1156.2 Ų56.26%0.05932%0.317CS..Hα-helixtrans-64.5-45176.9-70.9-7.7000110.9I90 Y97 K241 L242 E243 D247 A248 M249I90-N245 WeakPolarHBondContact CG2-ND2 3.26Å; Y97-N245 HydrophobicContact CD1-CB 3.97Å; Y97-N245 HydrophobicContact CE1-CB 4.44Å; K241-N245 WeakPolarHBondContact CE-OD1 3.49Å; K241-N245 PolarHBondContact NZ-OD1 3.48Å; K241-N245 VanDerWaalsContact O-CG 3.28Å; K241-N245 PolarHBondContact O-N 3.47Å; K241-N245 PolarHBondContact O-OD1 2.69Å; L242-N245 PolarHBondContact O-N 3.14Å; E243-N245 VanDerWaalsContact C-N 3.33Å; E243-N245 PolarHBondContact O-N 2.87Å; N245-D247 VanDerWaalsContact C-N 3.31Å; N245-D247 PolarHBondContact O-N 2.98Å; N245-A248 PolarHBondContact O-N 3.02Å; N245-A248 VanDerWaalsContact O-N 3.16Å; N245-M249 PolarHBondContact O-N 3.45Å
246L97.9Very high91.1Very high3 Ų360.4 Ų60.42%0.01634%0.344CS..Hα-helixtrans-66.1-29.8177.6-74170.1000113.1M70 V100 K123 A124 L242 E243M70-L246 HydrophobicContact CE-CD2 4.13Å; V100-L246 HydrophobicContact CG2-CD2 4.12Å; K123-L246 HydrophobicContact CB-CD1 4.02Å; K123-L246 HydrophobicContact CD-CB 4.02Å; K123-L246 HydrophobicContact CD-CD1 3.86Å; K123-L246 HydrophobicContact CG-CB 4.14Å; K123-L246 HydrophobicContact CG-CD1 3.82Å; A124-L246 HydrophobicContact CB-CD2 4.33Å; L242-L246 WeakPolarHBondContact O-CB 3.18Å; L242-L246 WeakPolarHBondContact O-CG 3.47Å; L242-L246 PolarHBondContact O-N 3.2Å; E243-L246 PolarHBondContact O-N 3.32Å
247D96.5Very high90.1Very high104 Ų10457.3 Ų57.356%0.55634%0.338SS*.Hα-helixtrans-76.6-26.4173-72.6-35.5000112.9K123 E243 Q244 N245K123-D247 WeakPolarHBondContact CE-OD1 3.38Å; K123-D247 IonicContact NZ-OD1 2.86Å; K123-D247 PolarHBondContact NZ-OD1 3.4Å; K123-D247 IonicContact NZ-OD2 2.64Å; K123-D247 PolarHBondContact NZ-OD2 2.84Å; E243-D247 WeakPolarHBondContact O-CB 3.44Å; E243-D247 PolarHBondContact O-N 3.43Å; E243-D247 VanDerWaalsContact O-OD2 3.11Å; Q244-D247 PolarHBondContact O-N 3.09Å; N245-D247 VanDerWaalsContact C-N 3.31Å; N245-D247 PolarHBondContact O-N 2.98Å
248A95.5Very high88.6Confident53 Ų5356.2 Ų56.244%0.43834%0.335SS..Hα-helixtrans-82.9-13177.200000113.4Y97 Q244 N245Y97-A248 HydrophobicContact CD1-CB 4.38Å; Y97-A248 HydrophobicContact CD2-CB 4.43Å; Y97-A248 HydrophobicContact CE1-CB 3.98Å; Y97-A248 HydrophobicContact CE2-CB 4.04Å; Q244-A248 WeakPolarHBondContact O-CB 3.2Å; Q244-A248 PolarHBondContact O-N 3.1Å; N245-A248 PolarHBondContact O-N 3.02Å; N245-A248 VanDerWaalsContact O-N 3.16Å
249M93Very high86.8Confident12 Ų1261.1 Ų61.16%0.05937%0.37CS..SBendtrans-69.9136.9-179.2-172.8-172.368.700111.4M70 Y98 C127 Y128 N245 A251M70-M249 HydrophobicContact CE-CE 3.77Å; M70-M249 HydrophobicContact CE-SD 3.13Å; M70-M249 WeakPolarHBondContact CE-SD 3.4Å; Y98-M249 HydrophobicContact CD1-CG 4.39Å; Y98-M249 HydrophobicContact CD1-SD 3.62Å; Y98-M249 HydrophobicContact CD2-CG 4.39Å; Y98-M249 HydrophobicContact CE1-CE 4.4Å; Y98-M249 HydrophobicContact CE1-CG 3.9Å; Y98-M249 HydrophobicContact CE1-SD 3.42Å; Y98-M249 WeakPolarHBondContact CE1-SD 3.27Å; Y98-M249 HydrophobicContact CE2-CG 3.94Å; Y98-M249 HydrophobicContact CE2-SD 4.4Å; Y98-M249 HydrophobicContact CG-SD 4.19Å; C127-M249 HydrophobicContact CB-CE 3.64Å; Y128-M249 HydrophobicContact CD2-CE 4.24Å; Y128-M249 HydrophobicContact CD2-SD 4.37Å; N245-M249 PolarHBondContact O-N 3.45Å; M249-A251 PolarHBondContact O-N 3.13Å
250P88.1Confident84.8Confident82 Ų8264.7 Ų64.753%0.53239%0.385SS..PPolyproline II helixtrans-57.6124.8165.9-21.433.1000110.8Y98Y98-P250 PolarHBondContact OH-O 3.17Å
251A83.1Confident82.7Confident80 Ų8065.5 Ų65.566%0.66139%0.394SS*.SBendtrans-73.4136.7-176.500000112.1M249M249-A251 PolarHBondContact O-N 3.13Å
252A81.2Confident80.1Confident29 Ų2967.6 Ų67.624%0.2442%0.418CS..SBendtrans41.162.9167.200000115.6C127 Q129 G254C127-A252 PolarHBondContact O-N 2.59Å; Q129-A252 HydrophobicContact CB-CB 4.21Å; Q129-A252 HydrophobicContact CG-CB 4.31Å; A252-G254 PolarHBondContact O-N 2.81Å
253P78.1Confident77.8Confident20 Ų2076.3 Ų76.313%0.1345%0.452CS..  trans-58.2138.5178.527.3-37.2000111.6R45 D67 Y98 Y128R45-P253 PolarHBondContact NH1-O 2.94Å; D67-P253 HydrophobicContact CB-CB 4.22Å; D67-P253 HydrophobicContact CB-CG 3.9Å; D67-P253 VanDerWaalsContact O-CG 3.28Å; D67-P253 WeakPolarHBondContact O-CG 3.42Å; Y98-P253 HydrophobicContact CE1-CG 4.11Å; Y98-P253 WeakPolarHBondContact OH-CG 3.39Å; Y128-P253 HydrophobicContact CE2-CG 4.42Å
254G71.1Confident75.4Confident69 Ų6977.2 Ų77.271%0.71147%0.47SS*.  trans-113.3124.6173.700000110.7A252A252-G254 PolarHBondContact O-N 2.81Å
255V74.3Confident72.9Confident33 Ų3381.2 Ų81.220%0.249%0.486CS..  trans-126.4149.3173.1-173.50000106.9Q44 R68 I257Q44-V255 VanDerWaalsContact NE2-CB 3.29Å; Q44-V255 PolarHBondContact NE2-O 2.85Å; Q44-V255 VanDerWaalsContact NE2-O 3.09Å; Q44-V255 PolarHBondContact OE1-O 3.33Å; R68-V255 HydrophobicContact CG-CG2 4.21Å; V255-I257 PolarHBondContact O-N 2.84Å
256P70.7Confident70.1Confident98 Ų9885.6 Ų85.664%0.63652%0.516SS*.PPolyproline II helixtrans-59.2137171.2-24.835.3000111.3H258P256-H258 PolarHBondContact O-N 3.39Å
257I76.2Confident67.5Low81 Ų8190.9 Ų90.942%0.41555%0.554SS.*PPolyproline II helixtrans-67.7121172.3-63.6174.8000108T41 V255T41-I257 WeakPolarHBondContact O-CG2 3.5Å; V255-I257 PolarHBondContact O-N 2.84Å
258H67.4Low64.9Low132 Ų13292.6 Ų92.661%0.61156%0.562SS**PPolyproline II helixtrans-85.1131.8171.2-66.7-49.8000109.9P256P256-H258 PolarHBondContact O-N 3.39Å
259S60.9Low62.5Low109 Ų10995 Ų9576%0.76257%0.573SS**PPolyproline II helixtrans-66.8148.1168.648.80000110.2
260K57.1Low60.2Low106 Ų106102.7 Ų102.746%0.46161%0.607SS.*PPolyproline II helixtrans-50.2140.4171.2-61.2-175.2-163.8-172.80110E38 T41 C262E38-K260 WeakPolarHBondContact OE1-CE 3.14Å; E38-K260 IonicContact OE1-NZ 2.6Å; E38-K260 PolarHBondContact OE1-NZ 3.04Å; E38-K260 WeakPolarHBondContact OE2-CE 3.49Å; E38-K260 IonicContact OE2-NZ 2.63Å; E38-K260 PolarHBondContact OE2-NZ 3.2Å; T41-K260 HydrophobicContact CG2-CD 4.47Å; T41-K260 HydrophobicContact CG2-CG 3.63Å; K260-C262 PolarHBondContact O-N 3Å
261P53.3Low58.2Low93 Ų93107.6 Ų107.660%0.60462%0.62SS**PPolyproline II helixtrans-52.3132.1161.7-19.930.9000108.2Y263P261-Y263 VanDerWaalsContact C-N 3.31Å; P261-Y263 WeakPolarHBondContact O-CD2 3.18Å; P261-Y263 PolarHBondContact O-N 3.41Å
262C44.1Very low56.1Low126 Ų126110.1 Ų110.185%0.85162%0.618SS**  trans-66.199.8170.4-157.50000106K260 A264K260-C262 PolarHBondContact O-N 3Å; C262-A264 PolarHBondContact O-N 3.47Å
263Y50.5Low54.3Low185 Ų185114 Ų11473%0.72564%0.64SS**  trans-69.374.7162.8-62-81.6000106.1P261 F265P261-Y263 VanDerWaalsContact C-N 3.31Å; P261-Y263 WeakPolarHBondContact O-CD2 3.18Å; P261-Y263 PolarHBondContact O-N 3.41Å; Y263-F265 VanDerWaalsContact C-N 3.27Å; Y263-F265 PolarHBondContact O-N 2.78Å
264A47.6Very low52.9Low81 Ų81121.6 Ų121.667%0.66967%0.674SS**  trans-54.6109.6151.100000103.4C262 C266C262-A264 PolarHBondContact O-N 3.47Å; A264-C266 PolarHBondContact O-N 3.46Å
265F46.7Very low51.5Low198 Ų198128.4 Ų128.487%0.86868%0.68SS**  trans-52.694.1174.9-79.8-94.5000106.8Y263 S267Y263-F265 VanDerWaalsContact C-N 3.27Å; Y263-F265 PolarHBondContact O-N 2.78Å; F265-S267 VanDerWaalsContact C-N 3.34Å; F265-S267 PolarHBondContact O-N 2.74Å
266C39.3Very low50.3Low103 Ų103133.4 Ų133.470%0.69671%0.711SS**  trans-63.1110.9161-168.30000102.6A264 L268A264-C266 PolarHBondContact O-N 3.46Å; C266-L268 PolarHBondContact O-N 3.42Å
267S42.1Very low49Very low114 Ų114134.2 Ų134.280%0.79771%0.714SS**  trans-63.272.5177.951.90000109.1F265F265-S267 VanDerWaalsContact C-N 3.34Å; F265-S267 PolarHBondContact O-N 2.74Å
268L42.9Very low47.8Very low140 Ų140135.3 Ų135.373%0.73372%0.72SS**  trans-79.1132.3162.9-72.6172.8000106.6C266 F270C266-L268 PolarHBondContact O-N 3.42Å; L268-F270 PolarHBondContact O-N 3.32Å
269P44.7Very low47Very low103 Ų103137.5 Ų137.567%0.66973%0.733SS**  trans-58134.4177.37.8-7.2000108.9F271P269-F271 VanDerWaalsContact C-N 3.33Å; P269-F271 PolarHBondContact O-N 2.97Å
270F45.7Very low46.5Very low175 Ų175136.8 Ų136.877%0.76872%0.724SS**  trans-58.194.8174.8-175-103.2000108.9L268 Q272L268-F270 PolarHBondContact O-N 3.32Å; F270-Q272 HydrophobicContact CD1-CG 3.8Å; F270-Q272 HydrophobicContact CE1-CG 3.44Å; F270-Q272 VanDerWaalsContact CE1-CG 3.44Å; F270-Q272 HydrophobicContact CZ-CG 4.47Å; F270-Q272 PolarHBondContact O-N 3.3Å
271F45.7Very low46.1Very low185 Ų185138.5 Ų138.581%0.81174%0.743SS**  trans-71.4110.1166.6-108.5-91.7000106.4P269 P273P269-F271 VanDerWaalsContact C-N 3.33Å; P269-F271 PolarHBondContact O-N 2.97Å; F271-P273 VanDerWaalsContact O-CD 3.24Å; F271-P273 WeakPolarHBondContact O-CD 3.29Å
272Q38.4Very low45.6Very low133 Ų133138.6 Ų138.662%0.62174%0.739SS**PPolyproline II helixtrans-67.8116.1160.9-77-167.7-27.100106.6F270 E274F270-Q272 HydrophobicContact CD1-CG 3.8Å; F270-Q272 HydrophobicContact CE1-CG 3.44Å; F270-Q272 VanDerWaalsContact CE1-CG 3.44Å; F270-Q272 HydrophobicContact CZ-CG 4.47Å; F270-Q272 PolarHBondContact O-N 3.3Å; Q272-E274 PolarHBondContact O-N 2.92Å
273P44.6Very low45.8Very low109 Ų109138.2 Ų138.271%0.70872%0.724SS**PPolyproline II helixtrans-60.1135.9170.624.7-30.9000108.5F271 Y275F271-P273 VanDerWaalsContact O-CD 3.24Å; F271-P273 WeakPolarHBondContact O-CD 3.29Å; P273-Y275 PolarHBondContact O-N 3.01Å
274E46.8Very low45.7Very low180 Ų180134 Ų13484%0.84172%0.72SS**PPolyproline II helixtrans-55.6129.9168.1-72.4178.2166.800108.1Q272 V276Q272-E274 PolarHBondContact O-N 2.92Å; E274-V276 PolarHBondContact O-N 2.96Å
275Y42.9Very low45.8Very low213 Ų213130.8 Ų130.884%0.83570%0.695SS**  trans-60.2106.3179.6-67.2-88000109P273 T277P273-Y275 PolarHBondContact O-N 3.01Å; Y275-T277 PolarHBondContact O-N 3.41Å
276V48.9Very low45.9Very low138 Ų138124.6 Ų124.684%0.83667%0.668SS**  trans-76.4108.9166.8-174.40000106.2E274 D278E274-V276 PolarHBondContact O-N 2.96Å; V276-D278 PolarHBondContact O-N 3.16Å
277T42.4Very low46Very low115 Ų115123.3 Ų123.371%0.70665%0.653SS**  trans-70.9119168.447.60000108.2Y275 M279Y275-T277 PolarHBondContact O-N 3.41Å; T277-M279 PolarHBondContact O-N 3Å
278D52.3Low46.4Very low104 Ų104125.1 Ų125.156%0.55664%0.643SS**  trans-59.5132.2171-159.6-14.8000109.6V276 T280V276-D278 PolarHBondContact O-N 3.16Å; D278-T280 VanDerWaalsContact CG-OG1 3.31Å; D278-T280 PolarHBondContact OD1-N 3.12Å; D278-T280 PolarHBondContact OD1-OG1 3.31Å; D278-T280 PolarHBondContact OD2-OG1 3.16Å
279M51.2Low46.7Very low177 Ų177124.6 Ų124.687%0.87264%0.637SS**  trans-108.75.8179.9-72.4-112.2-64.500111.5T277T277-M279 PolarHBondContact O-N 3Å
280T49Very low46.6Very low94 Ų94125 Ų12558%0.57763%0.63SS**  trans-69.3146.8174.255.90000111.2D278D278-T280 VanDerWaalsContact CG-OG1 3.31Å; D278-T280 PolarHBondContact OD1-N 3.12Å; D278-T280 PolarHBondContact OD1-OG1 3.31Å; D278-T280 PolarHBondContact OD2-OG1 3.16Å
281V49.9Very low46.5Very low142 Ų142121.4 Ų121.486%0.86162%0.616SS**  trans-88.9111.4173.2178.90000107
282D42.8Very low46.4Very low96 Ų96119.9 Ų119.951%0.51361%0.611SS.*  trans-56.1137.5177.2-63.8-12.3000111E286D282-E286 WeakPolarHBondContact CA-OE2 3.46Å; D282-E286 HydrophobicContact CB-CB 4.24Å; D282-E286 WeakPolarHBondContact CB-OE2 3.28Å; D282-E286 VanDerWaalsContact CG-OE2 3.3Å
283H48.1Very low46.2Very low117 Ų117121.9 Ų121.954%0.54262%0.62SS.*  trans-62142.3175.1-174.4-88.3000109.2G285 E286H283-G285 PolarHBondContact ND1-N 3.17Å; H283-G285 VanDerWaalsContact ND1-N 3.19Å; H283-G285 PolarHBondContact O-N 3.25Å; H283-E286 HydrophobicContact CB-CG 4.09Å; H283-E286 WeakPolarHBondContact CB-OE1 3.3Å; H283-E286 PolarHBondContact N-OE1 3.16Å; H283-E286 VanDerWaalsContact O-CB 3.24Å; H283-E286 WeakPolarHBondContact O-CB 3.31Å; H283-E286 WeakPolarHBondContact O-CG 3.15Å; H283-E286 PolarHBondContact O-N 3.36Å
284P47.9Very low45.6Very low97 Ų97119.5 Ų119.563%0.6362%0.616SS**G310 helixtrans-59.6-18.4-176.919.9-32.1000114.4E286P284-E286 VanDerWaalsContact C-N 3.31Å
285G49.4Very low45Very low14 Ų14120.8 Ų120.814%0.14462%0.622CS.*G310 helixtrans-71.4-21.3169.800000114.5R146 H283 M287R146-G285 PolarHBondContact NH1-O 3.35Å; R146-G285 PolarHBondContact NH2-O 3.11Å; H283-G285 PolarHBondContact ND1-N 3.17Å; H283-G285 VanDerWaalsContact ND1-N 3.19Å; H283-G285 PolarHBondContact O-N 3.25Å; G285-M287 PolarHBondContact O-N 2.97Å; G285-M287 VanDerWaalsContact O-N 3.14Å
286E48.6Very low44.5Very low67 Ų67113.7 Ų113.731%0.31361%0.613SS.*G310 helixtrans-68.7-16-176.8-65173-14800112.6F26 D282 H283 P284F26-E286 VanDerWaalsContact CE1-CD 3.46Å; F26-E286 HydrophobicContact CE1-CG 3.6Å; F26-E286 WeakPolarHBondContact CE1-OE1 3.44Å; F26-E286 HydrophobicContact CZ-CG 3.91Å; D282-E286 WeakPolarHBondContact CA-OE2 3.46Å; D282-E286 HydrophobicContact CB-CB 4.24Å; D282-E286 WeakPolarHBondContact CB-OE2 3.28Å; D282-E286 VanDerWaalsContact CG-OE2 3.3Å; H283-E286 HydrophobicContact CB-CG 4.09Å; H283-E286 WeakPolarHBondContact CB-OE1 3.3Å; H283-E286 PolarHBondContact N-OE1 3.16Å; H283-E286 VanDerWaalsContact O-CB 3.24Å; H283-E286 WeakPolarHBondContact O-CB 3.31Å; H283-E286 WeakPolarHBondContact O-CG 3.15Å; H283-E286 PolarHBondContact O-N 3.36Å; P284-E286 VanDerWaalsContact C-N 3.31Å
287M42.3Very low43.5Very low76 Ų76118.3 Ų118.337%0.37462%0.615SS.*SBendtrans-72.6125.9176.6-53.3-59.3-79.700110.7G285 E291G285-M287 PolarHBondContact O-N 2.97Å; G285-M287 VanDerWaalsContact O-N 3.14Å; M287-E291 VanDerWaalsContact CA-OE2 3.32Å; M287-E291 WeakPolarHBondContact CA-OE2 3.35Å; M287-E291 HydrophobicContact CB-CB 4.2Å; M287-E291 HydrophobicContact CE-CB 3.57Å
288Y49.5Very low42.9Very low152 Ų152119.7 Ų119.760%0.59662%0.618SS**  trans-65.5153.5168-70.7-87.1000109.5V181 H290 E291V181-Y288 HydrophobicContact CG2-CD1 4.07Å; V181-Y288 HydrophobicContact CG2-CE1 4.09Å; Y288-H290 PolarHBondContact O-N 2.57Å; Y288-E291 PolarHBondContact N-OE2 2.89Å; Y288-E291 VanDerWaalsContact N-OE2 3.14Å; Y288-E291 WeakPolarHBondContact O-CB 3.32Å; Y288-E291 PolarHBondContact O-N 3.09Å
289E50.3Low41.8Very low130 Ų130120.2 Ų120.261%0.60762%0.621SS**Hα-helixtrans-51.2-27.8179.6-68.7179.8168.600113E291E289-E291 VanDerWaalsContact C-N 3.35Å
290H42.5Very low40.9Very low111 Ų111122.1 Ų122.151%0.51462%0.619SS.*Hα-helixtrans-73.6-20.2175.5-67.4-47.8000115.6Y212 Y288Y212-H290 AromaticContact CE1-CE1 3.4Å; Y212-H290 VanDerWaalsContact CE1-CE1 3.4Å; Y212-H290 WeakPolarHBondContact CE1-CE1 3.33Å; Y212-H290 AromaticContact CE1-NE2 3.32Å; Y212-H290 VanDerWaalsContact CE1-NE2 3.32Å; Y212-H290 WeakPolarHBondContact CE1-NE2 3.39Å; Y212-H290 AromaticContact CZ-CE1 3.5Å; Y212-H290 AromaticContact CZ-NE2 3.54Å; Y212-H290 PolarHBondContact OH-CE1 2.91Å; Y212-H290 PolarHBondContact OH-NE2 3.47Å; Y212-H290 VanDerWaalsContact OH-NE2 3.08Å; Y288-H290 PolarHBondContact O-N 2.57Å
291E42.2Very low39.9Very low100 Ų100127 Ų12747%0.46763%0.627SS.*Hα-helixtrans-89.6-16.9-178.1-58.5179.3151.600111.6M287 Y288 E289M287-E291 VanDerWaalsContact CA-OE2 3.32Å; M287-E291 WeakPolarHBondContact CA-OE2 3.35Å; M287-E291 HydrophobicContact CB-CB 4.2Å; M287-E291 HydrophobicContact CE-CB 3.57Å; Y288-E291 PolarHBondContact N-OE2 2.89Å; Y288-E291 VanDerWaalsContact N-OE2 3.14Å; Y288-E291 WeakPolarHBondContact O-CB 3.32Å; Y288-E291 PolarHBondContact O-N 3.09Å; E289-E291 VanDerWaalsContact C-N 3.35Å
292E44.2Very low39Very low152 Ų152125.3 Ų125.371%0.7162%0.621SS**Hα-helixtrans-74.3-29.5168.9-71.4-167.7169.200112.7G294E292-G294 PolarHBondContact O-N 3.39Å
293E35.4Very low38.5Very low176 Ų176130.3 Ų130.382%0.82264%0.638SS**SBendtrans-919.6-176.8-66.3-163.9159.200114.7E295E293-E295 PolarHBondContact O-N 3.39Å
294G31.6Very low37.5Very low59 Ų59129.1 Ų129.161%0.60865%0.648SS**  trans-93.959.8-176.400000115.7E292 G296E292-G294 PolarHBondContact O-N 3.39Å; G294-G296 VanDerWaalsContact C-N 3.26Å; G294-G296 PolarHBondContact O-N 2.94Å
295E33.8Very low36.7Very low207 Ų207132.1 Ų132.197%0.96766%0.658SS**  trans-67.288.1160.6-79.7-165.6168.800109.7E293E293-E295 PolarHBondContact O-N 3.39Å
296G32.4Very low35.6Very low63 Ų63142.6 Ų142.665%0.64969%0.693SS**  trans131.280159.300000116.4G294G294-G296 VanDerWaalsContact C-N 3.26Å; G294-G296 PolarHBondContact O-N 2.94Å
297R26.9Very low34.7Very low235 Ų235148.2 Ų148.289%0.88772%0.719SS**  trans-169.782132.2-106.7169.6-176.9179.32109.6D299R297-D299 PolarHBondContact O-N 3.26Å
298N31.5Very low34.1Very low145 Ų145151.5 Ų151.578%0.77574%0.738SS**  trans-65.277.2158.3-104.8-28.1000108.6R300N298-R300 VanDerWaalsContact C-N 3.31Å
299D28.6Very low33.4Very low114 Ų114151.4 Ų151.461%0.6175%0.748SS**  trans-99.564165.2-123.6-17.7000108.1R297 R301R297-D299 PolarHBondContact O-N 3.26Å; D299-R301 PolarHBondContact O-N 3.39Å; D299-R301 IonicContact OD1-NE 2.77Å
300R32.4Very low32.7Very low218 Ų218153.6 Ų153.682%0.82376%0.764SS**  trans-68.772.2164.6-72-176.7178.5-176.7-2.7108.6N298 S302N298-R300 VanDerWaalsContact C-N 3.31Å; R300-S302 PolarHBondContact O-N 2.79Å
301R27.8Very low32.4Very low197 Ų197154.9 Ų154.974%0.74377%0.773SS**  trans-82.981.9160.2-73.6-173-175.8-177.10.1107.7D299 F303D299-R301 PolarHBondContact O-N 3.39Å; D299-R301 IonicContact OD1-NE 2.77Å; R301-F303 PolarHBondContact O-N 3Å; R301-F303 VanDerWaalsContact O-N 3.11Å
302S30.8Very low32.1Very low106 Ų106155.4 Ų155.474%0.74178%0.779SS**  trans-53.8112.3158.542.70000108R300 A304R300-S302 PolarHBondContact O-N 2.79Å; S302-A304 VanDerWaalsContact C-N 3.26Å; S302-A304 PolarHBondContact O-N 3.08Å
303F31.7Very low31.9Very low201 Ų201154.5 Ų154.588%0.88278%0.778SS**  trans-68.593.9164.7-84.5-92.6000106.9R301 I305R301-F303 PolarHBondContact O-N 3Å; R301-F303 VanDerWaalsContact O-N 3.11Å; F303-I305 PolarHBondContact O-N 2.56Å; F303-I305 VanDerWaalsContact O-N 3.16Å
304A28.4Very low32Very low91 Ų91150.9 Ų150.975%0.75277%0.768SS**  trans-62.5113172.100000108.9S302 R306S302-A304 VanDerWaalsContact C-N 3.26Å; S302-A304 PolarHBondContact O-N 3.08Å; A304-R306 PolarHBondContact O-N 3.45Å
305I30.3Very low32.2Very low160 Ų160156 Ų15682%0.82178%0.777SS**  trans-65.7125.1170.2-61.4173.7000107F303 E307F303-I305 PolarHBondContact O-N 2.56Å; F303-I305 VanDerWaalsContact O-N 3.16Å; I305-E307 PolarHBondContact O-N 3.09Å
306R26.7Very low32.3Very low235 Ų235153 Ų15389%0.88777%0.766SS**  trans-72.5116.6168.7-81.6-179.4168.2179.8-4.6107.8A304 D308A304-R306 PolarHBondContact O-N 3.45Å; R306-D308 PolarHBondContact O-N 3.2Å; R306-D308 VanDerWaalsContact O-N 3.1Å
307E29.3Very low32.5Very low184 Ų184156 Ų15686%0.8677%0.772SS**  trans-58.2104.6164.9-68.5177.8161.200108.5I305I305-E307 PolarHBondContact O-N 3.09Å
308D29.7Very low32.9Very low146 Ų146153 Ų15378%0.78177%0.768SS**  trans-169.392.5156.8-91.1-30.4000106.5R306R306-D308 PolarHBondContact O-N 3.2Å; R306-D308 VanDerWaalsContact O-N 3.1Å
309N36.1Very low33Very low149 Ų149153.7 Ų153.780%0.79777%0.772SS**  trans169.992.7142.9-82.3-27.6000109I311N309-I311 PolarHBondContact O-N 3.38Å
310D33.7Very low33.2Very low176 Ų176157.5 Ų157.594%0.94179%0.786SS**  trans-59.6102.9160.3-75.7-40.2000108.7
311I36.8Very low33.2Very low139 Ų139155.9 Ų155.971%0.71379%0.787SS**  trans-96.3103.9167.1-57.9-178.8000107.5N309 L313N309-I311 PolarHBondContact O-N 3.38Å; I311-L313 PolarHBondContact O-N 3.26Å
312D35.9Very low33.4Very low111 Ų111157.9 Ų157.959%0.59480%0.795SS**  trans-68.6105.8173-175.9-8.7000110.3T314D312-T314 PolarHBondContact O-N 3.25Å; D312-T314 VanDerWaalsContact O-N 3.09Å; D312-T314 WeakPolarHBondContact OD1-CB 3.21Å; D312-T314 WeakPolarHBondContact OD1-CG2 3.35Å; D312-T314 PolarHBondContact OD1-N 3Å; D312-T314 PolarHBondContact OD1-OG1 3.13Å; D312-T314 PolarHBondContact OD2-OG1 3.3Å
313L39.7Very low33.6Very low132 Ų132160.6 Ų160.669%0.69180%0.8SS**G310 helixtrans-64.7-5.1-178.4-78.3156.4000114.3I311 Q315 L316I311-L313 PolarHBondContact O-N 3.26Å; L313-Q315 PolarHBondContact O-N 3.16Å; L313-L316 HydrophobicContact CD2-CD1 4.18Å
314T37.9Very low33.6Very low100 Ų100158.3 Ų158.361%0.61380%0.797SS**G310 helixtrans-70.2-16-179.5560000114.3D312D312-T314 PolarHBondContact O-N 3.25Å; D312-T314 VanDerWaalsContact O-N 3.09Å; D312-T314 WeakPolarHBondContact OD1-CB 3.21Å; D312-T314 WeakPolarHBondContact OD1-CG2 3.35Å; D312-T314 PolarHBondContact OD1-N 3Å; D312-T314 PolarHBondContact OD1-OG1 3.13Å; D312-T314 PolarHBondContact OD2-OG1 3.3Å
315Q35.4Very low33.9Very low168 Ų168161.2 Ų161.279%0.78580%0.799SS**G310 helixtrans-81.7-11.1179.7-66.7-163.5500115.2L313 V317L313-Q315 PolarHBondContact O-N 3.16Å; Q315-V317 PolarHBondContact O-N 3.35Å
316L36.4Very low34.2Very low142 Ų142160.7 Ų160.774%0.74380%0.803SS**G310 helixtrans-82.4-9.6-177.3-82.9160.5000114.4L313L313-L316 HydrophobicContact CD2-CD1 4.18Å
317V36.9Very low34.7Very low126 Ų126156.5 Ų156.576%0.76480%0.798SS**G310 helixtrans-93.4-4.2-172.8-169.80000113.6Q315Q315-V317 PolarHBondContact O-N 3.35Å
318Q35.7Very low34.9Very low174 Ų174156.5 Ų156.581%0.81380%0.799SS**SBendtrans-102.53.1-172.4-75.4-167.7-11.900117.6
319N32.5Very low35.5Very low159 Ų159163.3 Ų163.385%0.8582%0.821SS**  trans-120.343.8-175.1-80.6-21000115
320Q33.4Very low35.4Very low194 Ų194164 Ų16491%0.90782%0.822SS**  trans-118.915.5176.4-133.7167.48.100115.9
321E31.9Very low35.5Very low183 Ų183163.4 Ų163.486%0.85582%0.816SS**  trans-118.5111.6171.9-70-172.9168.900111.5
322R32Very low35.5Very low239 Ų239164.7 Ų164.790%0.90282%0.822SS**  trans146.682.3147.1-82.9-172.7-75.3-154-1.6111.8
323I34.2Very low35.4Very low164 Ų164167.9 Ų167.984%0.84184%0.835SS**  trans-141.574.8153.4-50.7178.4000107.4
324D32.5Very low35.2Very low153 Ų153170.1 Ų170.182%0.81884%0.844SS**  trans-143.3109.1159.3-80.1-37.2000104.7
325D34.1Very low35Very low151 Ų151174.8 Ų174.881%0.80786%0.859SS**  trans159.985.6158.4-82-16.2000108.3
326V38.3Very low34.9Very low150 Ų150175.3 Ų175.391%0.90987%0.865SS**  trans-119.482.3159.4-175.50000106.5
327D36.6Very low34.8Very low146 Ų146177.8 Ų177.878%0.78187%0.874SS**  trans-86.8147.1173.4-98.7-19.6000111.9
328E32.9Very low34.7Very low185 Ų185182.2 Ų182.286%0.86488%0.883SS**  trans-50141.1-175.3-61.4172.7142.800115.9
329K41.7Very low34.6Very low288 Ų288182.9 Ų182.9100%1.25289%0.89SS**  trans-145.30143-91-167.9-178173.10111.8

Retrieved 329 of 329 residues in 276.7 ms (Link to these results)