A0A077Z4J8_TRITR Loading...

cystathionine beta-synthase

AlphaFold DB , UniProt , Accession A0A077Z4J8, Species TRITR (Trichuris trichiura, Whipworm), Gene n/a, Length 517 aa.

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Site Residue pLDDT pLDDT confidence pLDDT10 pLDDT10 confidence SASA SASA [Ų] SASA10 SASA10 [Ų] RSA RSA unformatted RSA10 RSA10 unformatted Surface Surface10 (not used) Disorder (not used) Disorder Sec. str. Secondary structure Isomer Phi (φ) Psi (ψ) Omega (ω) Chi 1 (χ1) Chi 2 (χ2) Chi 3 (χ3) Chi 4 (χ4) Chi 5 (χ5) Tau (τ) Contacts (colored by PAE) Contact details
1M35.5Very low45.4Very low245 Ų245125.1 Ų125.1100%1.20769%0.694SS**  0129.30-60.7-172.3-150.700105.9
2D34.2Very low47.4Very low137 Ų137123.9 Ų123.973%0.73369%0.686SS**  trans-53.6137.6-152.190.565000114.9T4D2-T4 PolarHBondContact O-N 3.06Å; D2-T4 PolarHBondContact OD1-N 2.97Å; D2-T4 PolarHBondContact OD1-OG1 2.97Å
3G33Very low49.3Very low83 Ų83116.2 Ų116.286%0.85665%0.646SS**  trans-94.344-170.600000114.2
4T34.8Very low51.6Low114 Ų114109 Ų10970%0.69961%0.606SS**  trans-120.862172.4530000112.2D2 K6D2-T4 PolarHBondContact O-N 3.06Å; D2-T4 PolarHBondContact OD1-N 2.97Å; D2-T4 PolarHBondContact OD1-OG1 2.97Å; T4-K6 VanDerWaalsContact C-N 3.31Å; T4-K6 PolarHBondContact O-N 3.24Å
5A37.8Very low53.7Low99 Ų99108.7 Ų108.782%0.81860%0.603SS**  trans-65.994.9163.500000108.4K7A5-K7 PolarHBondContact O-N 3.34Å
6K42.7Very low55.6Low169 Ų169110.6 Ų110.674%0.73561%0.606SS**  trans-50.4111.1165-86.2-178.2176178.10106.8T4 Y8T4-K6 VanDerWaalsContact C-N 3.31Å; T4-K6 PolarHBondContact O-N 3.24Å; K6-Y8 VanDerWaalsContact C-N 3.25Å; K6-Y8 VanDerWaalsContact O-CD2 3.29Å; K6-Y8 WeakPolarHBondContact O-CD2 3.48Å; K6-Y8 PolarHBondContact O-N 2.91Å
7K46.8Very low57.4Low208 Ų208109.5 Ų109.590%0.90459%0.59SS**  trans-65.292.4171.6-128.2-179.3-177.6-177.80105.8A5 L9A5-K7 PolarHBondContact O-N 3.34Å; K7-L9 PolarHBondContact O-N 2.68Å
8Y54.9Low59.3Low115 Ų115106.6 Ų106.645%0.45157%0.571SS.*  trans-57.6138.6168.5-63.8-81.1000107.2K6 A10 F39K6-Y8 VanDerWaalsContact C-N 3.25Å; K6-Y8 VanDerWaalsContact O-CD2 3.29Å; K6-Y8 WeakPolarHBondContact O-CD2 3.48Å; K6-Y8 PolarHBondContact O-N 2.91Å; Y8-A10 PolarHBondContact O-N 2.7Å; Y8-F39 HydrophobicContact CD1-CB 3.99Å; Y8-F39 HydrophobicContact CD1-CD2 4.43Å; Y8-F39 HydrophobicContact CD2-CB 4.37Å; Y8-F39 AromaticContact CD2-CD2 3.76Å; Y8-F39 HydrophobicContact CD2-CD2 3.76Å; Y8-F39 HydrophobicContact CE1-CD2 4.35Å; Y8-F39 AromaticContact CE2-CD2 3.68Å; Y8-F39 HydrophobicContact CE2-CD2 3.68Å; Y8-F39 HydrophobicContact CE2-CE2 4.31Å; Y8-F39 HydrophobicContact CG-CB 3.9Å; Y8-F39 HydrophobicContact CG-CD2 4.14Å; Y8-F39 AromaticContact CZ-CD2 3.99Å
9L54.2Low61Low131 Ų131106.3 Ų106.369%0.68656%0.561SS**  trans-62.2114.3170.8-71.8172.1000106.1K7 D11 P37K7-L9 PolarHBondContact O-N 2.68Å; L9-D11 PolarHBondContact O-N 3.47Å; L9-P37 HydrophobicContact CD1-CB 4.1Å
10A59.2Low62.6Low51 Ų51101 Ų10142%0.42153%0.534SS..  trans-53.8134.3167.900000107.2Y8 D12 A107Y8-A10 PolarHBondContact O-N 2.7Å; A10-D12 VanDerWaalsContact C-N 3.27Å; A10-D12 PolarHBondContact O-N 3.24Å; A10-A107 HydrophobicContact CB-CB 3.62Å
11D66.7Low64Low24 Ų2499 Ų9913%0.12852%0.523CS..  trans-66.996.5169.3-173.9-0.2000107.4L9 S13 N199 L200L9-D11 PolarHBondContact O-N 3.47Å; D11-S13 VanDerWaalsContact C-N 3.25Å; D11-S13 WeakPolarHBondContact OD1-CB 3.39Å; D11-S13 PolarHBondContact OD1-N 3.2Å; D11-S13 VanDerWaalsContact OD1-N 3.14Å; D11-S13 PolarHBondContact OD1-OG 2.97Å; D11-S13 PolarHBondContact OD2-OG 2.94Å; D11-N199 PolarHBondContact OD2-OD1 3.01Å; D11-L200 VanDerWaalsContact OD2-CB 3.3Å; D11-L200 WeakPolarHBondContact OD2-CB 3.37Å; D11-L200 PolarHBondContact OD2-N 3.19Å
12D69Low66.8Low111 Ų11189.6 Ų89.659%0.59448%0.476SS*.  trans-87.23-18065.3-8000111.9A10 V14 L15A10-D12 VanDerWaalsContact C-N 3.27Å; A10-D12 PolarHBondContact O-N 3.24Å; D12-V14 PolarHBondContact O-N 2.65Å; D12-L15 HydrophobicContact CB-CD1 4.01Å; D12-L15 HydrophobicContact CB-CG 4.41Å; D12-L15 WeakPolarHBondContact O-CB 2.94Å; D12-L15 PolarHBondContact O-N 3.49Å
13S72Confident69.5Low23 Ų2388.2 Ų88.216%0.16148%0.475CS..THydrogen-bonded Turntrans-59.8-21.3179.867.70000113.5D11D11-S13 VanDerWaalsContact C-N 3.25Å; D11-S13 WeakPolarHBondContact OD1-CB 3.39Å; D11-S13 PolarHBondContact OD1-N 3.2Å; D11-S13 VanDerWaalsContact OD1-N 3.14Å; D11-S13 PolarHBondContact OD1-OG 2.97Å; D11-S13 PolarHBondContact OD2-OG 2.94Å
14V81.2Confident72.3Confident16 Ų1687 Ų8710%0.09746%0.457CS..THydrogen-bonded Turntrans-85.7-17.6176.8-57.30000113.8D12 Q16 Y109 I192 L194 N199D12-V14 PolarHBondContact O-N 2.65Å; V14-Q16 VanDerWaalsContact C-N 3.33Å; V14-Y109 HydrophobicContact CG2-CD1 4.42Å; V14-Y109 HydrophobicContact CG2-CD2 4.25Å; V14-Y109 HydrophobicContact CG2-CE1 3.82Å; V14-Y109 HydrophobicContact CG2-CE2 3.66Å; V14-I192 HydrophobicContact CG2-CD1 4.19Å; V14-L194 VanDerWaalsContact CG1-O 3.24Å; V14-L194 WeakPolarHBondContact CG1-O 2.98Å; V14-N199 HydrophobicContact CG1-CB 4.28Å; V14-N199 WeakPolarHBondContact CG1-ND2 3.23Å
15L83.6Confident75Confident105 Ų10589.5 Ų89.555%0.5546%0.458SS..THydrogen-bonded Turntrans-79.8-18.3-175.1-61.3-177.2000112.9D12 Y109D12-L15 HydrophobicContact CB-CD1 4.01Å; D12-L15 HydrophobicContact CB-CG 4.41Å; D12-L15 WeakPolarHBondContact O-CB 2.94Å; D12-L15 PolarHBondContact O-N 3.49Å; L15-Y109 HydrophobicContact CD2-CD1 4.19Å; L15-Y109 HydrophobicContact CD2-CG 3.94Å
16Q84.8Confident77.6Confident139 Ų13986.8 Ų86.865%0.6543%0.432SS*.SBendtrans-127.3115.3175.3-67.7-175.5-400108.7V14 K18V14-Q16 VanDerWaalsContact C-N 3.33Å; Q16-K18 PolarHBondContact O-N 3.11Å
17W85.6Confident79.9Confident92 Ų9288.4 Ų88.435%0.34843%0.434SS..  trans-59.4134.1176.8-17788.5000110.7W19 K182W17-W19 AromaticContact CH2-CD2 3.56Å; W17-W19 HydrophobicContact CH2-CD2 3.56Å; W17-W19 AromaticContact CH2-CE2 3.56Å; W17-W19 AromaticContact CH2-CE3 3.76Å; W17-W19 HydrophobicContact CH2-CE3 3.76Å; W17-W19 HydrophobicContact CH2-CG 4.14Å; W17-W19 AromaticContact CH2-CH2 4Å; W17-W19 HydrophobicContact CH2-CH2 4Å; W17-W19 AromaticContact CH2-CZ2 3.8Å; W17-W19 HydrophobicContact CH2-CZ2 3.8Å; W17-W19 AromaticContact CH2-CZ3 3.97Å; W17-W19 HydrophobicContact CH2-CZ3 3.97Å; W17-W19 HydrophobicContact CZ2-CD2 4.17Å; W17-W19 AromaticContact CZ2-CE3 3.94Å; W17-W19 HydrophobicContact CZ2-CE3 3.94Å; W17-W19 HydrophobicContact CZ2-CH2 4.47Å; W17-W19 HydrophobicContact CZ2-CZ3 4.1Å; W17-W19 HydrophobicContact CZ3-CD2 4.4Å; W17-K182 HydrophobicContact CD2-CD 3.59Å; W17-K182 VanDerWaalsContact CD2-CE 3.44Å; W17-K182 HydrophobicContact CD2-CG 4.13Å; W17-K182 HydrophobicContact CE3-CD 4.06Å; W17-K182 HydrophobicContact CG-CD 3.9Å; W17-K182 HydrophobicContact CG-CG 3.94Å; W17-K182 HydrophobicContact CH2-CD 4.33Å; W17-K182 HydrophobicContact CZ2-CD 3.93Å; W17-K182 HydrophobicContact CZ3-CD 4.41Å
18K91.4Very high82.2Confident57 Ų5780.7 Ų80.725%0.24840%0.399CS..  trans-147.7162.3175-67.2-169.4-177.5-179.30109.5Q16 E22Q16-K18 PolarHBondContact O-N 3.11Å; K18-E22 WeakPolarHBondContact CD-OE2 3.46Å; K18-E22 IonicContact NZ-OE1 2.85Å; K18-E22 PolarHBondContact NZ-OE1 3.17Å; K18-E22 IonicContact NZ-OE2 3.23Å; K18-E22 PolarHBondContact NZ-OE2 3.33Å
19W92.1Very high84Confident100 Ų10077 Ų7738%0.37939%0.393SS..  trans-60.8145.7175.9-69.6113.5000111.9W17 N21 E22 Y171 D172 R198W17-W19 AromaticContact CH2-CD2 3.56Å; W17-W19 HydrophobicContact CH2-CD2 3.56Å; W17-W19 AromaticContact CH2-CE2 3.56Å; W17-W19 AromaticContact CH2-CE3 3.76Å; W17-W19 HydrophobicContact CH2-CE3 3.76Å; W17-W19 HydrophobicContact CH2-CG 4.14Å; W17-W19 AromaticContact CH2-CH2 4Å; W17-W19 HydrophobicContact CH2-CH2 4Å; W17-W19 AromaticContact CH2-CZ2 3.8Å; W17-W19 HydrophobicContact CH2-CZ2 3.8Å; W17-W19 AromaticContact CH2-CZ3 3.97Å; W17-W19 HydrophobicContact CH2-CZ3 3.97Å; W17-W19 HydrophobicContact CZ2-CD2 4.17Å; W17-W19 AromaticContact CZ2-CE3 3.94Å; W17-W19 HydrophobicContact CZ2-CE3 3.94Å; W17-W19 HydrophobicContact CZ2-CH2 4.47Å; W17-W19 HydrophobicContact CZ2-CZ3 4.1Å; W17-W19 HydrophobicContact CZ3-CD2 4.4Å; W19-N21 VanDerWaalsContact CB-OD1 3.25Å; W19-N21 WeakPolarHBondContact CB-OD1 3.48Å; W19-N21 PolarHBondContact O-N 2.7Å; W19-N21 VanDerWaalsContact O-N 3.13Å; W19-E22 PolarHBondContact O-N 2.82Å; W19-Y171 HydrophobicContact CE3-CD2 4.3Å; W19-Y171 HydrophobicContact CE3-CE2 4.06Å; W19-Y171 HydrophobicContact CZ3-CD2 4.35Å; W19-Y171 HydrophobicContact CZ3-CE2 4.36Å; W19-D172 HydrophobicContact CH2-CB 3.94Å; W19-D172 HydrophobicContact CZ3-CB 4.13Å; W19-R198 PolarHBondContact O-NH1 3.46Å
20P92.4Very high85.7Confident1 Ų173 Ų731%0.00638%0.378CS..THydrogen-bonded Turntrans-69.1-11.1-176.334-40.6000112.7Y171 I178 Y197 F282 P284 T285P20-Y171 HydrophobicContact CG-CD2 4.32Å; P20-I178 HydrophobicContact CB-CD1 4.49Å; P20-I178 HydrophobicContact CG-CD1 3.84Å; P20-Y197 HydrophobicContact CB-CD2 4.02Å; P20-Y197 HydrophobicContact CB-CG 3.79Å; P20-F282 HydrophobicContact CB-CD2 4.23Å; P20-F282 HydrophobicContact CB-CE2 3.62Å; P20-F282 HydrophobicContact CB-CZ 4.05Å; P20-F282 HydrophobicContact CG-CD2 3.97Å; P20-F282 HydrophobicContact CG-CE1 4.43Å; P20-F282 HydrophobicContact CG-CE2 3.69Å; P20-F282 HydrophobicContact CG-CG 4.47Å; P20-F282 HydrophobicContact CG-CZ 3.94Å; P20-P284 CarbonylContact O-C 3.52Å; P20-P284 WeakPolarHBondContact O-CA 3.31Å; P20-T285 PolarHBondContact O-N 2.99Å; P20-T285 PolarHBondContact O-OG1 3.07Å
21N93.2Very high87.1Confident58 Ų5877.2 Ų77.231%0.3139%0.394SS..THydrogen-bonded Turntrans-106.612.4-177.872.1-21.7000114.5W19 Y171 F282 Y283W19-N21 VanDerWaalsContact CB-OD1 3.25Å; W19-N21 WeakPolarHBondContact CB-OD1 3.48Å; W19-N21 PolarHBondContact O-N 2.7Å; W19-N21 VanDerWaalsContact O-N 3.13Å; N21-Y171 PolarHBondContact ND2-OH 2.92Å; N21-F282 HydrophobicContact CB-CB 4.17Å; N21-F282 HydrophobicContact CB-CD2 4.15Å; N21-Y283 WeakPolarHBondContact CA-O 3.45Å; N21-Y283 WeakPolarHBondContact CB-O 3.34Å
22E92.9Very high88.1Confident49 Ų4978.7 Ų78.723%0.22941%0.405CS..SBendtrans-61134.6173.5-164.6-171.3-173.600109K18 W19 A24 R198 T285K18-E22 WeakPolarHBondContact CD-OE2 3.46Å; K18-E22 IonicContact NZ-OE1 2.85Å; K18-E22 PolarHBondContact NZ-OE1 3.17Å; K18-E22 IonicContact NZ-OE2 3.23Å; K18-E22 PolarHBondContact NZ-OE2 3.33Å; W19-E22 PolarHBondContact O-N 2.82Å; E22-A24 PolarHBondContact O-N 3.19Å; E22-R198 IonicContact OE2-CZ 3.15Å; E22-R198 IonicContact OE2-NH1 3.47Å; E22-R198 PolarHBondContact OE2-NH1 3.2Å; E22-R198 IonicContact OE2-NH2 2.73Å; E22-R198 PolarHBondContact OE2-NH2 3.07Å; E22-T285 WeakPolarHBondContact O-CB 3.07Å; E22-T285 WeakPolarHBondContact O-CG2 3.45Å; E22-T285 PolarHBondContact O-OG1 3.02Å
23P92.3Very high89Confident108 Ų10883.2 Ų83.270%0.70142%0.42SS*.PPolyproline II helixtrans-55.7136.9177.1-27.835.4000112.5K25P23-K25 PolarHBondContact O-N 3.23Å
24A91.9Very high89.9Confident57 Ų5788.1 Ų88.147%0.47144%0.44SS..PPolyproline II helixtrans-62.2135178.300000111.7E22 C26 T285E22-A24 PolarHBondContact O-N 3.19Å; A24-C26 VanDerWaalsContact C-N 3.34Å; A24-T285 HydrophobicContact CB-CG2 4.14Å; A24-T285 WeakPolarHBondContact CB-O 3.14Å
25K91.3Very high90.2Very high166 Ų16692.8 Ų92.872%0.72247%0.471SS*.  trans-89.5-1.1173.4-60-177.6-177.1-1770113.3P23P23-K25 PolarHBondContact O-N 3.23Å
26C91.3Very high90.6Very high43 Ų4390.6 Ų90.629%0.29146%0.464SS..  trans-65.2132.3-178.2-175.40000110.9A24 R240A24-C26 VanDerWaalsContact C-N 3.34Å; C26-R240 PolarHBondContact SG-NH1 2.86Å
27R92.1Very high90.8Very high203 Ų20387.1 Ų87.177%0.76645%0.454SS*.  trans-98.917-179.9-61.4-176.3-179.7-177-0.5113.8A29R27-A29 PolarHBondContact O-N 3.41Å
28W94.2Very high91.1Very high46 Ų4685 Ų8517%0.17445%0.448CS..  trans-56.4139.7-179.7176.491.2000111.3A30 R240 E244W28-A30 HydrophobicContact CH2-CB 3.84Å; W28-A30 HydrophobicContact CZ2-CB 3.95Å; W28-R240 HydrophobicContact CD2-CB 4.24Å; W28-R240 VanDerWaalsContact CD2-CD 3.42Å; W28-R240 HydrophobicContact CD2-CG 3.65Å; W28-R240 HydrophobicContact CE3-CG 3.72Å; W28-R240 VanDerWaalsContact CE3-NE 3.34Å; W28-R240 HydrophobicContact CG-CG 4.44Å; W28-R240 HydrophobicContact CH2-CB 3.96Å; W28-R240 HydrophobicContact CH2-CG 3.62Å; W28-R240 VanDerWaalsContact CZ2-CA 3.45Å; W28-R240 HydrophobicContact CZ2-CB 3.46Å; W28-R240 VanDerWaalsContact CZ2-CB 3.46Å; W28-R240 HydrophobicContact CZ2-CG 3.54Å; W28-R240 WeakPolarHBondContact CZ2-O 3.5Å; W28-R240 HydrophobicContact CZ3-CG 3.71Å; W28-E244 HydrophobicContact CZ2-CG 4.22Å; W28-E244 PolarHBondContact NE1-OE1 2.77Å
29A92.5Very high91Very high38 Ų3884.6 Ų84.631%0.31445%0.446SS..  trans-147.3144.6167.400000108R27 N31 S32R27-A29 PolarHBondContact O-N 3.41Å; A29-N31 PolarHBondContact O-N 3.01Å; A29-S32 VanDerWaalsContact O-CB 3.31Å; A29-S32 WeakPolarHBondContact O-CB 3.46Å; A29-S32 PolarHBondContact O-N 2.8Å
30A90.3Very high91.1Very high45 Ų4582.6 Ų82.637%0.37244%0.441SS..THydrogen-bonded Turntrans-57.5-24.6-174.800000114.4W28 K243W28-A30 HydrophobicContact CH2-CB 3.84Å; W28-A30 HydrophobicContact CZ2-CB 3.95Å; A30-K243 HydrophobicContact CB-CB 4.06Å
31N88Confident91.1Very high141 Ų14184 Ų8475%0.75445%0.448SS*.THydrogen-bonded Turntrans-110.713.717965.2-19000113.3A29 K33A29-N31 PolarHBondContact O-N 3.01Å; N31-K33 PolarHBondContact O-N 2.77Å
32S88.8Confident91Very high54 Ų5489.6 Ų89.638%0.37847%0.472SS..  trans-64134.7179.8-173.20000110.9A29 E34A29-S32 VanDerWaalsContact O-CB 3.31Å; A29-S32 WeakPolarHBondContact O-CB 3.46Å; A29-S32 PolarHBondContact O-N 2.8Å; S32-E34 PolarHBondContact OG-N 2.92Å
33K87.9Confident91.1Very high207 Ų20790.5 Ų90.590%0.947%0.474SS*.  trans-95.7-5.4170.4-63.2-176.6-179.4179.90112.2N31N31-K33 PolarHBondContact O-N 2.77Å
34E89.9Confident91.1Very high126 Ų12689.9 Ų89.959%0.58947%0.469SS*.SBendtrans-69.3132.7178.1-63.7-172.5174.200109.6S32 S36S32-E34 PolarHBondContact OG-N 2.92Å; E34-S36 PolarHBondContact O-N 3.14Å
35P88.6Confident90.9Very high114 Ų11490.2 Ų90.274%0.7446%0.46SS*.PPolyproline II helixtrans-63135.9176.826.5-33.3000109.8
36S90.8Very high90.7Very high59 Ų5992.1 Ų92.141%0.41347%0.468SS..PPolyproline II helixtrans-59.8130.2174179.30000110.2E34 H38 H40E34-S36 PolarHBondContact O-N 3.14Å; S36-H38 PolarHBondContact O-N 2.77Å; S36-H38 PolarHBondContact OG-CD2 3.09Å; S36-H38 PolarHBondContact OG-N 3.31Å; S36-H40 VanDerWaalsContact CB-NE2 3.34Å; S36-H40 WeakPolarHBondContact CB-NE2 3.42Å; S36-H40 PolarHBondContact OG-NE2 3.2Å
37P89.8Confident90.6Very high66 Ų6692.8 Ų92.843%0.42947%0.471SS..  trans-77.1-8.3174.631.4-34.3000112.8L9L9-P37 HydrophobicContact CD1-CB 4.1Å
38H90.6Very high90.7Very high48 Ų4886.2 Ų86.222%0.22245%0.454CS..SBendtrans-88.7152.1-172.1-52-57000112S36 H40 L200 I204S36-H38 PolarHBondContact O-N 2.77Å; S36-H38 PolarHBondContact OG-CD2 3.09Å; S36-H38 PolarHBondContact OG-N 3.31Å; H38-H40 PolarHBondContact O-CD2 2.8Å; H38-H40 VanDerWaalsContact O-CD2 3.28Å; H38-L200 WeakPolarHBondContact CE1-CD1 3.5Å; H38-L200 WeakPolarHBondContact ND1-CD1 3.22Å; H38-I204 HydrophobicContact CB-CD1 3.66Å
39F90.6Very high90.8Very high47 Ų4794.5 Ų94.521%0.20649%0.492CS..  trans-70.1129.7167.5174.8-90.3000109.7Y8 E41 R99 R106 I204Y8-F39 HydrophobicContact CD1-CB 3.99Å; Y8-F39 HydrophobicContact CD1-CD2 4.43Å; Y8-F39 HydrophobicContact CD2-CB 4.37Å; Y8-F39 AromaticContact CD2-CD2 3.76Å; Y8-F39 HydrophobicContact CD2-CD2 3.76Å; Y8-F39 HydrophobicContact CE1-CD2 4.35Å; Y8-F39 AromaticContact CE2-CD2 3.68Å; Y8-F39 HydrophobicContact CE2-CD2 3.68Å; Y8-F39 HydrophobicContact CE2-CE2 4.31Å; Y8-F39 HydrophobicContact CG-CB 3.9Å; Y8-F39 HydrophobicContact CG-CD2 4.14Å; Y8-F39 AromaticContact CZ-CD2 3.99Å; F39-E41 HydrophobicContact CE1-CG 3.84Å; F39-E41 HydrophobicContact CZ-CG 4.31Å; F39-R99 PolarHBondContact O-NH2 3.24Å; F39-R106 VanDerWaalsContact CE1-NH2 3.26Å; F39-I204 WeakPolarHBondContact O-CD1 3.32Å
40H94Very high91Very high59 Ų5999.9 Ų99.927%0.27351%0.514SS..  trans-117.5131.3176.3-72.7-81.5000110.5S36 H38 Y207 D208S36-H40 VanDerWaalsContact CB-NE2 3.34Å; S36-H40 WeakPolarHBondContact CB-NE2 3.42Å; S36-H40 PolarHBondContact OG-NE2 3.2Å; H38-H40 PolarHBondContact O-CD2 2.8Å; H38-H40 VanDerWaalsContact O-CD2 3.28Å; H40-Y207 AromaticContact CE1-CD1 3.69Å; H40-Y207 AromaticContact CE1-CE1 3.43Å; H40-Y207 VanDerWaalsContact CE1-CE1 3.43Å; H40-Y207 WeakPolarHBondContact CE1-CE1 2.93Å; H40-Y207 AromaticContact ND1-CD1 3.78Å; H40-Y207 AromaticContact ND1-CE1 3.68Å; H40-D208 WeakPolarHBondContact CA-OD2 3.31Å; H40-D208 IonicContact CE1-OD1 2.64Å; H40-D208 IonicContact CG-OD1 3.75Å; H40-D208 IonicContact ND1-OD1 3.19Å; H40-D208 PolarHBondContact ND1-OD1 3Å; H40-D208 IonicContact ND1-OD2 3.11Å
41E92.2Very high91.4Very high31 Ų31101.2 Ų101.215%0.14551%0.514CS..PPolyproline II helixtrans-81.7132.5170.8-101.7145.8-134.800110.5F39 K45 R99 D208F39-E41 HydrophobicContact CE1-CG 3.84Å; F39-E41 HydrophobicContact CZ-CG 4.31Å; E41-K45 WeakPolarHBondContact OE2-CE 3.4Å; E41-K45 IonicContact OE2-NZ 3.5Å; E41-K45 PolarHBondContact OE2-NZ 3.07Å; E41-R99 IonicContact OE1-CZ 4Å; E41-R99 IonicContact OE1-NE 2.78Å; E41-R99 IonicContact OE1-NH1 3.96Å; E41-R99 PolarHBondContact OE1-NH1 3.04Å; E41-R99 IonicContact OE2-NH1 3.81Å; E41-R99 PolarHBondContact OE2-NH1 3.43Å; E41-D208 HydrophobicContact CB-CB 4.44Å; E41-D208 PolarHBondContact N-OD2 2.93Å
42Q91.8Very high91.8Very high175 Ų17598.4 Ų98.482%0.81850%0.504SS*.PPolyproline II helixtrans-68.4139.8176.1-66.1-176.1-5.100111.4Q209Q42-Q209 PolarHBondContact O-NE2 2.83Å
43Y94.5Very high92.3Very high68 Ų6898.7 Ų98.727%0.26750%0.501SS..SBendtrans-101.7141.4168.4179.3-91.6000110.4E212 E213 D216Y43-E212 HydrophobicContact CD1-CB 3.77Å; Y43-E212 HydrophobicContact CD2-CB 3.88Å; Y43-E212 HydrophobicContact CE1-CB 4.37Å; Y43-E212 HydrophobicContact CE2-CB 4.47Å; Y43-E212 HydrophobicContact CG-CB 3.5Å; Y43-E212 VanDerWaalsContact CG-CB 3.5Å; Y43-E212 HydrophobicContact CG-CG 4.34Å; Y43-E213 HydrophobicContact CD2-CG 4.34Å; Y43-E213 HydrophobicContact CE2-CB 4.31Å; Y43-E213 HydrophobicContact CE2-CG 3.53Å; Y43-D216 HydrophobicContact CE1-CB 3.79Å; Y43-D216 PolarHBondContact OH-OD2 3.03Å
44P91.6Very high92.7Very high94 Ų9492.1 Ų92.161%0.6148%0.478SS*.SBendcis-77.5145.6-8.531.6-34000111.8K46P44-K46 PolarHBondContact O-N 3.02Å
45K88Confident93.1Very high65 Ų6586.5 Ų86.528%0.28345%0.452SS..PPolyproline II helixtrans-61.9120.3168.2-78.6-176.1-180-166.50109.7E41 V47E41-K45 WeakPolarHBondContact OE2-CE 3.4Å; E41-K45 IonicContact OE2-NZ 3.5Å; E41-K45 PolarHBondContact OE2-NZ 3.07Å; K45-V47 PolarHBondContact O-N 2.89Å
46K87.6Confident93.5Very high206 Ų20685.9 Ų85.990%0.89644%0.436SS*.PPolyproline II helixtrans-66.5122.8171.8-68.3-177.5-179.8178.20109.4P44P44-K46 PolarHBondContact O-N 3.02Å
47V89.8Confident93.8Very high57 Ų5784.9 Ų84.935%0.34543%0.431SS..  trans-118136.4173.8-67.80000110.1K45 L51 Y56K45-V47 PolarHBondContact O-N 2.89Å; V47-L51 HydrophobicContact CB-CD2 4.16Å; V47-Y56 HydrophobicContact CG1-CD1 4.39Å
48P94Very high94.2Very high64 Ų6482.3 Ų82.342%0.41641%0.414SS..  trans-68.6161.9174.730.6-36.4000111.1I50 P52P48-I50 VanDerWaalsContact C-N 3.31Å; P48-I50 WeakPolarHBondContact CG-O 3.33Å; P48-I50 PolarHBondContact O-N 2.9Å; P48-P52 HydrophobicContact CG-CG 4.02Å
49K95.6Very high94.6Very high220 Ų22080.5 Ų80.596%0.95741%0.408SS*.SBendtrans-60.9-39.8177.7-68.8-174.6178.2-178.80112.6
50I97.5Very high94.9Very high151 Ų15182.8 Ų82.877%0.77442%0.415SS*.SBendtrans-101.6114.8171.3-60.3174.6000106.4P48P48-I50 VanDerWaalsContact C-N 3.31Å; P48-I50 WeakPolarHBondContact CG-O 3.33Å; P48-I50 PolarHBondContact O-N 2.9Å
51L97.5Very high95.1Very high73 Ų7380.1 Ų80.138%0.38240%0.403SS..  trans-67.8130.4-179.7-57.3-175.6000109.9V47 N53 A57V47-L51 HydrophobicContact CB-CD2 4.16Å; L51-N53 VanDerWaalsContact C-N 3.25Å; L51-N53 PolarHBondContact O-N 3.36Å; L51-A57 HydrophobicContact CD1-CB 4.02Å
52P97.4Very high95.3Very high82 Ų8281 Ų8153%0.53241%0.411SS..SBendtrans-63.6-30.7-177.8-24.535.2000113.6P48 Y56P48-P52 HydrophobicContact CG-CG 4.02Å; P52-Y56 HydrophobicContact CB-CD2 4.21Å; P52-Y56 HydrophobicContact CB-CE2 3.9Å; P52-Y56 HydrophobicContact CG-CD2 4.11Å; P52-Y56 HydrophobicContact CG-CE1 4.25Å; P52-Y56 HydrophobicContact CG-CE2 3.83Å; P52-Y56 HydrophobicContact CG-CG 4.44Å
53N97.9Very high95.7Very high61 Ų6174.5 Ų74.533%0.32638%0.382SS..SBendtrans-161.2176.717260.155.7000109.7L51 L55 Y56 V134L51-N53 VanDerWaalsContact C-N 3.25Å; L51-N53 PolarHBondContact O-N 3.36Å; N53-L55 PolarHBondContact O-N 2.85Å; N53-L55 VanDerWaalsContact OD1-CB 3.24Å; N53-L55 WeakPolarHBondContact OD1-CB 3.27Å; N53-L55 PolarHBondContact OD1-N 3.23Å; N53-Y56 PolarHBondContact O-N 2.84Å; N53-Y56 WeakPolarHBondContact OD1-CD2 3.4Å; N53-V134 HydrophobicContact CB-CG1 4.03Å
54V97.9Very high95.8Very high68 Ų6873.9 Ų73.941%0.41239%0.385SS..G310 helixtrans-64.4-22.8-175.575.40000114Y56 A57 A88 M130 V134V54-Y56 PolarHBondContact O-N 3.49Å; V54-A57 VanDerWaalsContact O-CB 3.28Å; V54-A57 WeakPolarHBondContact O-CB 3.05Å; V54-A57 PolarHBondContact O-N 3.31Å; V54-A88 HydrophobicContact CG2-CB 3.73Å; V54-M130 HydrophobicContact CG1-CG 4.33Å; V54-M130 HydrophobicContact CG1-SD 4.34Å; V54-V134 HydrophobicContact CG1-CG2 3.79Å
55L97.9Very high96.1Very high8 Ų875.8 Ų75.84%0.04238%0.38CS..G310 helixtrans-66.3-26.5179.4-52.2-179.8000111.8N53 A57 V58 L98 M130 V131 V134 K135N53-L55 PolarHBondContact O-N 2.85Å; N53-L55 VanDerWaalsContact OD1-CB 3.24Å; N53-L55 WeakPolarHBondContact OD1-CB 3.27Å; N53-L55 PolarHBondContact OD1-N 3.23Å; L55-A57 PolarHBondContact O-N 3.37Å; L55-V58 WeakPolarHBondContact O-CB 3.36Å; L55-V58 WeakPolarHBondContact O-CG2 3.37Å; L55-V58 PolarHBondContact O-N 3.31Å; L55-V58 VanDerWaalsContact O-N 3.11Å; L55-L98 HydrophobicContact CB-CD1 4.09Å; L55-L98 HydrophobicContact CB-CD2 4.37Å; L55-L98 HydrophobicContact CD1-CD1 4.01Å; L55-M130 HydrophobicContact CD2-CE 4.03Å; L55-M130 HydrophobicContact CD2-CG 4.17Å; L55-V131 HydrophobicContact CD1-CG1 4.41Å; L55-V131 HydrophobicContact CD2-CB 4.45Å; L55-V131 HydrophobicContact CD2-CG2 3.86Å; L55-V134 HydrophobicContact CD1-CB 3.97Å; L55-V134 HydrophobicContact CD1-CG1 3.74Å; L55-V134 HydrophobicContact CD2-CB 4.42Å; L55-V134 HydrophobicContact CD2-CG2 4.2Å; L55-V134 HydrophobicContact CG-CB 4.14Å; L55-V134 HydrophobicContact CG-CG1 3.95Å; L55-V134 HydrophobicContact CG-CG2 4.2Å; L55-K135 HydrophobicContact CD1-CD 4.27Å; L55-K135 HydrophobicContact CD1-CG 4.23Å
56Y97.2Very high96.6Very high102 Ų10273.1 Ų73.140%0.437%0.369SS..G310 helixtrans-71.7-4.1171.7-72.4-102.7000113.3V47 P52 N53 V54 R60V47-Y56 HydrophobicContact CG1-CD1 4.39Å; P52-Y56 HydrophobicContact CB-CD2 4.21Å; P52-Y56 HydrophobicContact CB-CE2 3.9Å; P52-Y56 HydrophobicContact CG-CD2 4.11Å; P52-Y56 HydrophobicContact CG-CE1 4.25Å; P52-Y56 HydrophobicContact CG-CE2 3.83Å; P52-Y56 HydrophobicContact CG-CG 4.44Å; N53-Y56 PolarHBondContact O-N 2.84Å; N53-Y56 WeakPolarHBondContact OD1-CD2 3.4Å; V54-Y56 PolarHBondContact O-N 3.49Å; Y56-R60 PolarHBondContact O-NH2 2.79Å
57A97.2Very high96.9Very high37 Ų3767.4 Ų67.431%0.30635%0.348SS..G310 helixtrans-91.6-0.4169.500000112.9L51 V54 L55 A88L51-A57 HydrophobicContact CD1-CB 4.02Å; V54-A57 VanDerWaalsContact O-CB 3.28Å; V54-A57 WeakPolarHBondContact O-CB 3.05Å; V54-A57 PolarHBondContact O-N 3.31Å; L55-A57 PolarHBondContact O-N 3.37Å; A57-A88 HydrophobicContact CB-CB 4.34Å
58V98Very high97.1Very high13 Ų1371.9 Ų71.98%0.07936%0.359CS..SBendtrans-77.6132.3171.7179.80000110L55 R60 A88 D94 R95 L98 M130L55-V58 WeakPolarHBondContact O-CB 3.36Å; L55-V58 WeakPolarHBondContact O-CG2 3.37Å; L55-V58 PolarHBondContact O-N 3.31Å; L55-V58 VanDerWaalsContact O-N 3.11Å; V58-R60 PolarHBondContact O-NH2 3.3Å; V58-A88 HydrophobicContact CG2-CB 4.29Å; V58-D94 HydrophobicContact CG1-CB 4.07Å; V58-D94 HydrophobicContact CG2-CB 4Å; V58-R95 HydrophobicContact CG1-CB 4.36Å; V58-R95 HydrophobicContact CG1-CG 3.87Å; V58-L98 HydrophobicContact CB-CD2 4.11Å; V58-L98 HydrophobicContact CG1-CD2 4.41Å; V58-L98 HydrophobicContact CG2-CD2 4.42Å; V58-M130 HydrophobicContact CG2-CE 4.13Å
59G97.8Very high96.9Very high9 Ų969.3 Ų69.39%0.09334%0.341CS..SBendtrans90-170.9-176.200000114T61 N87G59-T61 PolarHBondContact O-N 2.92Å; G59-N87 PolarHBondContact N-OD1 3.24Å
60R97.6Very high96.7Very high96 Ų9659.1 Ų59.136%0.36230%0.299SS..  trans54.639-176.3-62.9164.9-70.2-68-16.6112.7Y56 V58 E213Y56-R60 PolarHBondContact O-NH2 2.79Å; V58-R60 PolarHBondContact O-NH2 3.3Å; R60-E213 PolarHBondContact N-OE1 3.37Å; R60-E213 PolarHBondContact N-OE2 3.1Å
61T97.6Very high96.5Very high3 Ų359.8 Ų59.82%0.01830%0.296CS..  trans-74.9150.4-17555.50000111.6G59 K82 C83 E84 R95 E213 Q217G59-T61 PolarHBondContact O-N 2.92Å; T61-K82 PolarHBondContact O-NZ 3.44Å; T61-K82 WeakPolarHBondContact OG1-CE 3.22Å; T61-K82 PolarHBondContact OG1-NZ 3.29Å; T61-K82 VanDerWaalsContact OG1-NZ 3.07Å; T61-C83 WeakPolarHBondContact CB-O 3.24Å; T61-E84 WeakPolarHBondContact CB-OE1 3.13Å; T61-E84 WeakPolarHBondContact CG2-OE1 3.25Å; T61-E84 PolarHBondContact OG1-OE1 2.87Å; T61-R95 PolarHBondContact OG1-NH2 2.98Å; T61-R95 VanDerWaalsContact OG1-NH2 3.17Å; T61-E213 PolarHBondContact N-OE2 3Å; T61-Q217 PolarHBondContact O-NE2 3.5Å
62P98Very high96.2Very high49 Ų4961.9 Ų61.932%0.31830%0.304SS..  trans-63.4145-179.9-22.333.9000113.1V64 C83 F86P62-V64 HydrophobicContact CB-CG2 3.94Å; P62-C83 PolarHBondContact O-N 3.23Å; P62-F86 HydrophobicContact CG-CD2 3.82Å; P62-F86 HydrophobicContact CG-CE2 4.08Å; P62-F86 HydrophobicContact CG-CG 4.16Å
63L98.5Very high96Very high39 Ų3959.7 Ų59.720%0.20429%0.293CS..EExtended strand (participates in β ladder)trans-107.8116163.5-172.173.4000107.9L80 V81 K82 Q217 C218 V361L63-L80 HydrophobicContact CD1-CB 4.07Å; L63-L80 HydrophobicContact CD2-CD1 3.96Å; L63-L80 HydrophobicContact CG-CB 4.22Å; L63-L80 HydrophobicContact CG-CD1 4.46Å; L63-V81 CarbonylContact C-O 3.53Å; L63-V81 WeakPolarHBondContact CA-O 3.41Å; L63-K82 HydrophobicContact CD1-CB 4.11Å; L63-K82 HydrophobicContact CD1-CD 4.3Å; L63-Q217 HydrophobicContact CB-CB 4.18Å; L63-Q217 HydrophobicContact CB-CG 4.48Å; L63-Q217 HydrophobicContact CD2-CB 3.7Å; L63-C218 WeakPolarHBondContact CD2-SG 3.07Å; L63-V361 HydrophobicContact CD1-CG1 3.91Å
64V97.9Very high95.9Very high54 Ų5459.6 Ų59.633%0.32731%0.306SS..EExtended strand (participates in β ladder)trans-118.1137.5-169-177.30000109.9P62 L80 V81P62-V64 HydrophobicContact CB-CG2 3.94Å; V64-L80 CarbonylContact O-C 3.27Å; V64-L80 WeakPolarHBondContact O-CA 3.34Å; V64-V81 HydrophobicContact CB-CG2 3.96Å; V64-V81 PolarHBondContact N-O 3.14Å; V64-V81 WeakPolarHBondContact O-CG2 3.38Å; V64-V81 PolarHBondContact O-N 3.16Å
65R98.1Very high95.8Very high134 Ų13457.3 Ų57.351%0.50629%0.292SS..EExtended strand (participates in β ladder)trans-77.7134.4176.1-177179.8-64107.42.6111.3N67 E78 L80R65-N67 PolarHBondContact O-ND2 3.07Å; R65-E78 IonicContact CZ-OE1 3.27Å; R65-E78 IonicContact NE-OE1 2.76Å; R65-E78 PolarHBondContact NE-OE1 2.87Å; R65-E78 IonicContact NH2-OE1 2.75Å; R65-E78 PolarHBondContact NH2-OE1 3.29Å; R65-L80 HydrophobicContact CB-CD2 3.97Å; R65-L80 HydrophobicContact CG-CD2 4.29Å
66I97Very high95.8Very high10 Ų1064.5 Ų64.55%0.05132%0.323CS..  trans-87.1122.2170.3-60.2-61.1000109.1L69 L79 V81 L310 E314 I316 M344I66-L69 HydrophobicContact CG2-CB 3.79Å; I66-L79 HydrophobicContact CB-CB 4.22Å; I66-L79 HydrophobicContact CB-CD2 4.23Å; I66-L79 HydrophobicContact CB-CG 4.15Å; I66-L79 HydrophobicContact CG1-CD2 4.46Å; I66-L79 HydrophobicContact CG1-CG 4.21Å; I66-L79 HydrophobicContact CG2-CD2 4.15Å; I66-L79 PolarHBondContact N-O 3.42Å; I66-V81 HydrophobicContact CD1-CB 4.35Å; I66-V81 HydrophobicContact CD1-CG1 3.66Å; I66-V81 HydrophobicContact CD1-CG2 3.72Å; I66-V81 HydrophobicContact CG1-CG1 3.67Å; I66-V81 HydrophobicContact CG1-CG2 4.21Å; I66-L310 HydrophobicContact CD1-CD2 3.97Å; I66-E314 HydrophobicContact CD1-CB 4.44Å; I66-E314 HydrophobicContact CD1-CG 3.99Å; I66-E314 HydrophobicContact CG2-CG 4.23Å; I66-E314 WeakPolarHBondContact CG2-OE1 3.29Å; I66-I316 HydrophobicContact CD1-CD1 3.53Å; I66-M344 HydrophobicContact CG1-CE 4.13Å; I66-M344 HydrophobicContact CG2-CE 3.85Å
67N94.7Very high95.8Very high85 Ų8560.3 Ų60.346%0.45531%0.308SS..  trans-106.4-31-169.2-62.6-68.1000113.9R65 K71 E314R65-N67 PolarHBondContact O-ND2 3.07Å; N67-K71 VanDerWaalsContact O-CD 3.31Å; N67-K71 WeakPolarHBondContact O-CD 2.94Å; N67-K71 WeakPolarHBondContact O-CE 3.22Å; N67-E314 PolarHBondContact N-OE1 3.03Å; N67-E314 PolarHBondContact N-OE2 3.39Å
68R93.2Very high95.9Very high151 Ų15161.1 Ų61.157%0.5731%0.306SS*.SBendtrans-105.8-53.3-174.2-57.9-170.5-178.8167.6-5.4111.7G70 K71 E72 K313 E314R68-G70 PolarHBondContact O-N 3.27Å; R68-K71 PolarHBondContact O-N 2.87Å; R68-K71 VanDerWaalsContact O-N 3.14Å; R68-E72 WeakPolarHBondContact O-CG 3.06Å; R68-E72 PolarHBondContact O-N 2.91Å; R68-K313 HydrophobicContact CB-CB 4.31Å; R68-K313 VanDerWaalsContact CD-O 3.31Å; R68-K313 WeakPolarHBondContact CD-O 3.19Å; R68-K313 PolarHBondContact NH1-O 3.46Å; R68-E314 VanDerWaalsContact CA-OE1 3.31Å; R68-E314 WeakPolarHBondContact CA-OE1 3.33Å; R68-E314 WeakPolarHBondContact CB-OE1 3.41Å; R68-E314 PolarHBondContact N-OE1 2.87Å
69L90.2Very high95.9Very high10 Ų1060.8 Ų60.85%0.05230%0.303CS..Hα-helixtrans-59.6-43.8-174.1-76.3175.2000113.1I66 K71 E72 A73 A309 L310 K313 E314 M344I66-L69 HydrophobicContact CG2-CB 3.79Å; L69-K71 VanDerWaalsContact C-N 3.33Å; L69-K71 PolarHBondContact O-N 3.34Å; L69-E72 PolarHBondContact O-N 3.25Å; L69-A73 WeakPolarHBondContact O-CB 3.21Å; L69-A73 PolarHBondContact O-N 2.82Å; L69-A309 HydrophobicContact CD2-CB 3.88Å; L69-L310 HydrophobicContact CD1-CB 4.45Å; L69-L310 HydrophobicContact CD1-CD2 3.68Å; L69-L310 HydrophobicContact CD1-CG 3.87Å; L69-K313 HydrophobicContact CD2-CD 3.66Å; L69-K313 HydrophobicContact CG-CB 4.42Å; L69-K313 HydrophobicContact CG-CD 4.27Å; L69-E314 HydrophobicContact CD1-CG 4.16Å; L69-E314 HydrophobicContact CG-CG 4.37Å; L69-E314 PolarHBondContact N-OE1 3.47Å; L69-M344 HydrophobicContact CB-CE 3.96Å; L69-M344 HydrophobicContact CD1-CE 3.95Å
70G91.5Very high95.9Very high6 Ų660.9 Ų60.96%0.06230%0.302CS..Hα-helixtrans-60.7-41.7177.600000112.5R68 A73 G74 L75R68-G70 PolarHBondContact O-N 3.27Å; G70-A73 PolarHBondContact O-N 3.26Å; G70-G74 PolarHBondContact O-N 2.82Å; G70-L75 WeakPolarHBondContact O-CB 3.48Å; G70-L75 PolarHBondContact O-N 2.81Å
71K93.1Very high96Very high166 Ų16656.3 Ų56.372%0.72228%0.284SS*.Hα-helixtrans-68.3-43.7177.7-66-175.2-176.4177.80112.2N67 R68 L69 A73 G74N67-K71 VanDerWaalsContact O-CD 3.31Å; N67-K71 WeakPolarHBondContact O-CD 2.94Å; N67-K71 WeakPolarHBondContact O-CE 3.22Å; R68-K71 PolarHBondContact O-N 2.87Å; R68-K71 VanDerWaalsContact O-N 3.14Å; L69-K71 VanDerWaalsContact C-N 3.33Å; L69-K71 PolarHBondContact O-N 3.34Å; K71-A73 PolarHBondContact O-N 2.55Å; K71-G74 PolarHBondContact O-N 3.04Å
72E92.3Very high96Very high116 Ų11656.2 Ų56.254%0.54228%0.283SS..Hα-helixtrans-63.1-31.2177.2-71175.1174.500112.5R68 L69 G74 K313R68-E72 WeakPolarHBondContact O-CG 3.06Å; R68-E72 PolarHBondContact O-N 2.91Å; L69-E72 PolarHBondContact O-N 3.25Å; E72-G74 VanDerWaalsContact C-N 3.25Å; E72-G74 PolarHBondContact O-N 2.92Å; E72-K313 IonicContact OE1-NZ 3.33Å; E72-K313 PolarHBondContact OE1-NZ 3.45Å; E72-K313 WeakPolarHBondContact OE2-CD 3.33Å; E72-K313 IonicContact OE2-NZ 2.77Å; E72-K313 PolarHBondContact OE2-NZ 2.82Å
73A92.1Very high96Very high37 Ų3753.9 Ų53.931%0.30627%0.268SS..THydrogen-bonded Turntrans-80.8-0.717300000113.9L69 G70 K71 L75 L348L69-A73 WeakPolarHBondContact O-CB 3.21Å; L69-A73 PolarHBondContact O-N 2.82Å; G70-A73 PolarHBondContact O-N 3.26Å; K71-A73 PolarHBondContact O-N 2.55Å; A73-L75 VanDerWaalsContact C-N 3.35Å; A73-L75 HydrophobicContact CB-CG 4.23Å; A73-L348 HydrophobicContact CB-CB 4.47Å; A73-L348 HydrophobicContact CB-CD2 3.78Å
74G95.4Very high95.9Very high59 Ų5952 Ų5261%0.60826%0.259SS*.THydrogen-bonded Turntrans74.219.7179.400000114.8G70 K71 E72G70-G74 PolarHBondContact O-N 2.82Å; K71-G74 PolarHBondContact O-N 3.04Å; E72-G74 VanDerWaalsContact C-N 3.25Å; E72-G74 PolarHBondContact O-N 2.92Å
75L96.8Very high95.7Very high20 Ų2050.9 Ų50.911%0.10525%0.249CC..  trans-72.4139.2179-57.5-176.4000111.2G70 A73 L79 L348 A351 K352G70-L75 WeakPolarHBondContact O-CB 3.48Å; G70-L75 PolarHBondContact O-N 2.81Å; A73-L75 VanDerWaalsContact C-N 3.35Å; A73-L75 HydrophobicContact CB-CG 4.23Å; L75-L79 HydrophobicContact CD1-CD2 3.97Å; L75-L348 HydrophobicContact CD1-CD2 3.88Å; L75-A351 HydrophobicContact CD1-CB 3.93Å; L75-A351 HydrophobicContact CD2-CB 4.12Å; L75-K352 HydrophobicContact CD2-CB 4.41Å; L75-K352 HydrophobicContact CD2-CG 3.84Å
76K97.2Very high95.7Very high159 Ų15950.4 Ų50.469%0.69125%0.25SS*.  trans-96.1-24.6176.9-61.1-177.1-178.9-179.80113E356K76-E356 WeakPolarHBondContact O-CA 3.5Å
77C98.3Very high95.7Very high13 Ų1350.1 Ų50.19%0.08825%0.249CC..SBendtrans-74.9164178.865.40000112.2L354 K355 Q358C77-L354 HydrophobicContact CB-CB 3.59Å; C77-L354 HydrophobicContact CB-CD1 4.13Å; C77-K355 WeakPolarHBondContact CA-O 3.41Å; C77-Q358 WeakPolarHBondContact CA-O 3.34Å; C77-Q358 HydrophobicContact CB-CB 4.35Å; C77-Q358 VanDerWaalsContact CB-O 3.27Å; C77-Q358 WeakPolarHBondContact CB-O 3.49Å
78E98.2Very high95.8Very high55 Ų5548 Ų4826%0.25724%0.244SC..EExtended strand (participates in β ladder)trans-76.7123.7167.7-177.2173.9-14200109.8R65 L80 Q358 K359 C360R65-E78 IonicContact CZ-OE1 3.27Å; R65-E78 IonicContact NE-OE1 2.76Å; R65-E78 PolarHBondContact NE-OE1 2.87Å; R65-E78 IonicContact NH2-OE1 2.75Å; R65-E78 PolarHBondContact NH2-OE1 3.29Å; E78-L80 HydrophobicContact CG-CD2 3.82Å; E78-L80 HydrophobicContact CG-CG 4.06Å; E78-Q358 PolarHBondContact N-O 2.88Å; E78-K359 HydrophobicContact CB-CG 4.25Å; E78-K359 WeakPolarHBondContact O-CA 3.48Å; E78-K359 WeakPolarHBondContact OE2-CD 2.94Å; E78-K359 WeakPolarHBondContact OE2-CE 3Å; E78-C360 PolarHBondContact O-N 2.91Å
79L98.2Very high96Very high5 Ų541.1 Ų41.13%0.02622%0.219CC..EExtended strand (participates in β ladder)trans-104.2122.6177.7-171.861.5000110.1I66 L75 M344 A347 L348 C360 V362I66-L79 HydrophobicContact CB-CB 4.22Å; I66-L79 HydrophobicContact CB-CD2 4.23Å; I66-L79 HydrophobicContact CB-CG 4.15Å; I66-L79 HydrophobicContact CG1-CD2 4.46Å; I66-L79 HydrophobicContact CG1-CG 4.21Å; I66-L79 HydrophobicContact CG2-CD2 4.15Å; I66-L79 PolarHBondContact N-O 3.42Å; L75-L79 HydrophobicContact CD1-CD2 3.97Å; L79-M344 HydrophobicContact CD2-CE 3.38Å; L79-M344 HydrophobicContact CD2-SD 4.24Å; L79-M344 HydrophobicContact CG-CE 4.35Å; L79-A347 HydrophobicContact CD1-CB 4.45Å; L79-L348 HydrophobicContact CD2-CD2 3.89Å; L79-C360 HydrophobicContact CD1-CB 3.78Å; L79-V362 HydrophobicContact CD1-CG2 3.73Å
80L98.6Very high96.3Very high12 Ų1241 Ų416%0.06322%0.22CC..EExtended strand (participates in β ladder)trans-123147.3-175.9-56.3174.5000109.7L63 V64 R65 E78 K359 C360 V361 V362L63-L80 HydrophobicContact CD1-CB 4.07Å; L63-L80 HydrophobicContact CD2-CD1 3.96Å; L63-L80 HydrophobicContact CG-CB 4.22Å; L63-L80 HydrophobicContact CG-CD1 4.46Å; V64-L80 CarbonylContact O-C 3.27Å; V64-L80 WeakPolarHBondContact O-CA 3.34Å; R65-L80 HydrophobicContact CB-CD2 3.97Å; R65-L80 HydrophobicContact CG-CD2 4.29Å; E78-L80 HydrophobicContact CG-CD2 3.82Å; E78-L80 HydrophobicContact CG-CG 4.06Å; L80-K359 HydrophobicContact CD1-CD 4.15Å; L80-C360 PolarHBondContact N-O 3.06Å; L80-V361 HydrophobicContact CB-CG2 4.23Å; L80-V361 HydrophobicContact CD1-CG2 4.29Å; L80-V361 CarbonylContact O-C 3.59Å; L80-V361 WeakPolarHBondContact O-CA 3.02Å; L80-V362 PolarHBondContact O-N 3.39Å
81V98.1Very high96.5Very high0 Ų040.7 Ų40.70%022%0.217CC..EExtended strand (participates in β ladder)trans-122.5134.8175.1-70.60000111.2L63 V64 I66 I316 M344 V362 L364L63-V81 CarbonylContact C-O 3.53Å; L63-V81 WeakPolarHBondContact CA-O 3.41Å; V64-V81 HydrophobicContact CB-CG2 3.96Å; V64-V81 PolarHBondContact N-O 3.14Å; V64-V81 WeakPolarHBondContact O-CG2 3.38Å; V64-V81 PolarHBondContact O-N 3.16Å; I66-V81 HydrophobicContact CD1-CB 4.35Å; I66-V81 HydrophobicContact CD1-CG1 3.66Å; I66-V81 HydrophobicContact CD1-CG2 3.72Å; I66-V81 HydrophobicContact CG1-CG1 3.67Å; I66-V81 HydrophobicContact CG1-CG2 4.21Å; V81-I316 HydrophobicContact CG2-CD1 3.78Å; V81-M344 HydrophobicContact CG1-SD 4.37Å; V81-V362 CarbonylContact C-O 3.49Å; V81-V362 VanDerWaalsContact CA-O 3.27Å; V81-V362 WeakPolarHBondContact CA-O 3.24Å; V81-V362 HydrophobicContact CG1-CB 4.12Å; V81-L364 HydrophobicContact CB-CD1 3.64Å; V81-L364 HydrophobicContact CB-CG 3.86Å; V81-L364 HydrophobicContact CG1-CD1 3.83Å; V81-L364 HydrophobicContact CG1-CD2 4.15Å; V81-L364 HydrophobicContact CG1-CG 4Å; V81-L364 HydrophobicContact CG2-CD1 3.94Å
82K98.4Very high96.7Very high0 Ų032.8 Ų32.80%018%0.183CC..EExtended strand (participates in β ladder)trans-95.6107174.9-175.663165.3169.30108.6T61 L63 E84 E213 I214 V361 V362 L363 L364T61-K82 PolarHBondContact O-NZ 3.44Å; T61-K82 WeakPolarHBondContact OG1-CE 3.22Å; T61-K82 PolarHBondContact OG1-NZ 3.29Å; T61-K82 VanDerWaalsContact OG1-NZ 3.07Å; L63-K82 HydrophobicContact CD1-CB 4.11Å; L63-K82 HydrophobicContact CD1-CD 4.3Å; K82-E84 PolarHBondContact O-N 3.38Å; K82-E84 VanDerWaalsContact O-N 3.13Å; K82-E213 WeakPolarHBondContact CE-OE2 3.46Å; K82-E213 IonicContact NZ-OE2 3.91Å; K82-E213 PolarHBondContact NZ-OE2 2.92Å; K82-I214 HydrophobicContact CD-CG1 4.14Å; K82-I214 HydrophobicContact CG-CD1 4.34Å; K82-I214 HydrophobicContact CG-CG1 4.2Å; K82-V361 HydrophobicContact CB-CG1 4.39Å; K82-V362 PolarHBondContact N-O 3.04Å; K82-L363 HydrophobicContact CB-CD1 4.04Å; K82-L363 HydrophobicContact CG-CD1 3.93Å; K82-L364 PolarHBondContact O-N 3.31Å
83C97.1Very high96.9Very high0 Ų028.4 Ų28.40%016%0.162CC..EExtended strand (participates in β ladder)trans-86.379.6-166.9-61.20000112.1T61 P62 Y85 F86T61-C83 WeakPolarHBondContact CB-O 3.24Å; P62-C83 PolarHBondContact O-N 3.23Å; C83-Y85 HydrophobicContact CB-CD1 4.23Å; C83-Y85 HydrophobicContact CB-CE1 3.6Å; C83-Y85 HydrophobicContact CB-CE2 4.19Å; C83-Y85 PolarHBondContact O-N 2.89Å; C83-Y85 PolarHBondContact SG-OH 2.98Å; C83-F86 HydrophobicContact CB-CD2 3.59Å; C83-F86 HydrophobicContact CB-CE2 3.88Å; C83-F86 PolarHBondContact O-N 2.94Å
84E97.9Very high97.2Very high0 Ų026.7 Ų26.70%015%0.148CC..G310 helixtrans-72.4-10.4-177.1-69.9-65.9122.700114.6T61 K82 F86 N87 S91 V92 R95 L363 L364T61-E84 WeakPolarHBondContact CB-OE1 3.13Å; T61-E84 WeakPolarHBondContact CG2-OE1 3.25Å; T61-E84 PolarHBondContact OG1-OE1 2.87Å; K82-E84 PolarHBondContact O-N 3.38Å; K82-E84 VanDerWaalsContact O-N 3.13Å; E84-F86 PolarHBondContact O-N 3.48Å; E84-N87 PolarHBondContact O-N 3.12Å; E84-N87 PolarHBondContact O-ND2 2.92Å; E84-N87 PolarHBondContact OE2-ND2 3.23Å; E84-S91 CarbonylContact O-C 3.36Å; E84-S91 VanDerWaalsContact O-C 3.27Å; E84-V92 HydrophobicContact CB-CB 3.63Å; E84-V92 HydrophobicContact CB-CG2 4.17Å; E84-V92 HydrophobicContact CG-CB 3.89Å; E84-V92 HydrophobicContact CG-CG2 3.85Å; E84-R95 IonicContact OE1-CZ 2.72Å; E84-R95 IonicContact OE1-NE 3.16Å; E84-R95 PolarHBondContact OE1-NE 3.13Å; E84-R95 IonicContact OE1-NH2 3.06Å; E84-R95 PolarHBondContact OE1-NH2 2.8Å; E84-R95 WeakPolarHBondContact OE2-CD 3.42Å; E84-R95 IonicContact OE2-CZ 2.78Å; E84-R95 IonicContact OE2-NE 2.76Å; E84-R95 PolarHBondContact OE2-NE 3.39Å; E84-R95 IonicContact OE2-NH2 2.96Å; E84-R95 PolarHBondContact OE2-NH2 2.85Å; E84-L363 HydrophobicContact CG-CD1 3.61Å; E84-L363 HydrophobicContact CG-CG 4.29Å; E84-L364 WeakPolarHBondContact CB-O 3.32Å; E84-L364 PolarHBondContact N-O 3.45Å
85Y94.2Very high97.4Very high30 Ų3024.5 Ų24.512%0.11812%0.121CC..G310 helixtrans-72.4-4.2173.959-101.8000114.2C83 I316 C318 L364C83-Y85 HydrophobicContact CB-CD1 4.23Å; C83-Y85 HydrophobicContact CB-CE1 3.6Å; C83-Y85 HydrophobicContact CB-CE2 4.19Å; C83-Y85 PolarHBondContact O-N 2.89Å; C83-Y85 PolarHBondContact SG-OH 2.98Å; Y85-I316 HydrophobicContact CE1-CG2 3.94Å; Y85-I316 VanDerWaalsContact OH-CG2 3.23Å; Y85-I316 WeakPolarHBondContact OH-CG2 3.22Å; Y85-C318 HydrophobicContact CD1-CB 4.26Å; Y85-C318 HydrophobicContact CE1-CB 4.18Å; Y85-L364 HydrophobicContact CD1-CB 4.11Å; Y85-L364 HydrophobicContact CE1-CB 4.03Å; Y85-L364 HydrophobicContact CE1-CD1 4.02Å
86F96.6Very high97.4Very high124 Ų12423.6 Ų23.654%0.54412%0.116SC..G310 helixtrans-85.6-6.9171.3-81.1-80.9000114.3P62 C83 E84P62-F86 HydrophobicContact CG-CD2 3.82Å; P62-F86 HydrophobicContact CG-CE2 4.08Å; P62-F86 HydrophobicContact CG-CG 4.16Å; C83-F86 HydrophobicContact CB-CD2 3.59Å; C83-F86 HydrophobicContact CB-CE2 3.88Å; C83-F86 PolarHBondContact O-N 2.94Å; E84-F86 PolarHBondContact O-N 3.48Å
87N97.8Very high97.5Very high5 Ų516 Ų163%0.0278%0.083CC..SBendtrans-61.6157.8171.8-68.4-61.7000110.5G59 E84 G89 G90 S91 D94G59-N87 PolarHBondContact N-OD1 3.24Å; E84-N87 PolarHBondContact O-N 3.12Å; E84-N87 PolarHBondContact O-ND2 2.92Å; E84-N87 PolarHBondContact OE2-ND2 3.23Å; N87-G89 PolarHBondContact O-N 3.41Å; N87-G90 WeakPolarHBondContact O-CA 3.4Å; N87-G90 PolarHBondContact O-N 3.2Å; N87-S91 WeakPolarHBondContact CB-O 3.5Å; N87-S91 PolarHBondContact ND2-O 3.4Å; N87-S91 VanDerWaalsContact ND2-O 3.08Å; N87-D94 HydrophobicContact CB-CB 3.95Å; N87-D94 WeakPolarHBondContact CB-OD2 3.41Å
88A97.6Very high97.5Very high41 Ų4116 Ų1634%0.3398%0.082SC..THydrogen-bonded Turntrans-52.7-43-172.900000115.8V54 A57 V58 G90 D94 M130V54-A88 HydrophobicContact CG2-CB 3.73Å; A57-A88 HydrophobicContact CB-CB 4.34Å; V58-A88 HydrophobicContact CG2-CB 4.29Å; A88-G90 VanDerWaalsContact C-N 3.31Å; A88-D94 PolarHBondContact N-OD2 2.93Å; A88-M130 HydrophobicContact CB-CE 4.06Å; A88-M130 HydrophobicContact CB-SD 3.63Å
89G96Very high97.4Very high5 Ų513.6 Ų13.65%0.0527%0.071CC..THydrogen-bonded Turntrans-82.4-9.3176.600000113.2N87 D94 R369N87-G89 PolarHBondContact O-N 3.41Å; G89-D94 WeakPolarHBondContact CA-OD2 3.49Å; G89-D94 PolarHBondContact N-OD2 3.49Å; G89-R369 PolarHBondContact O-NH1 3.28Å; G89-R369 PolarHBondContact O-NH2 3.12Å
90G95.8Very high97.3Very high7 Ų713.3 Ų13.37%0.0727%0.069CC..SBendtrans92.818.4175.300000114.5N87 A88 D94 S367N87-G90 WeakPolarHBondContact O-CA 3.4Å; N87-G90 PolarHBondContact O-N 3.2Å; A88-G90 VanDerWaalsContact C-N 3.31Å; G90-D94 PolarHBondContact N-OD2 2.73Å; G90-S367 PolarHBondContact O-N 2.97Å
91S96.3Very high97.2Very high0 Ų012.8 Ų12.80%07%0.066CC..BIsolated β-bridgetrans-152.2165.3179.484.40000114.9E84 N87 K93 D94 P365E84-S91 CarbonylContact O-C 3.36Å; E84-S91 VanDerWaalsContact O-C 3.27Å; N87-S91 WeakPolarHBondContact CB-O 3.5Å; N87-S91 PolarHBondContact ND2-O 3.4Å; N87-S91 VanDerWaalsContact ND2-O 3.08Å; S91-K93 PolarHBondContact O-N 2.96Å; S91-K93 PolarHBondContact OG-N 3.33Å; S91-K93 VanDerWaalsContact OG-N 3.1Å; S91-D94 PolarHBondContact N-OD2 2.77Å; S91-D94 WeakPolarHBondContact O-CB 3.39Å; S91-D94 PolarHBondContact O-N 3.5Å; S91-D94 PolarHBondContact OG-OD1 2.97Å; S91-P365 CarbonylContact C-O 3.55Å; S91-P365 VanDerWaalsContact CA-O 3.29Å; S91-P365 WeakPolarHBondContact CA-O 3.38Å
92V97.1Very high97.1Very high1 Ų115.3 Ų15.31%0.0068%0.078CC..THydrogen-bonded Turntrans-59-24.6170.367.40000113.2E84 D94 R95 H206 L363 P365E84-V92 HydrophobicContact CB-CB 3.63Å; E84-V92 HydrophobicContact CB-CG2 4.17Å; E84-V92 HydrophobicContact CG-CB 3.89Å; E84-V92 HydrophobicContact CG-CG2 3.85Å; V92-D94 PolarHBondContact O-N 3.1Å; V92-R95 WeakPolarHBondContact O-CB 3.34Å; V92-R95 PolarHBondContact O-N 2.86Å; V92-H206 VanDerWaalsContact CG2-CE1 3.44Å; V92-H206 WeakPolarHBondContact CG2-CE1 3.22Å; V92-L363 HydrophobicContact CG2-CD2 4.4Å; V92-P365 HydrophobicContact CG1-CB 3.85Å; V92-P365 PolarHBondContact N-O 2.91Å
93K97.7Very high96.9Very high24 Ų2416.2 Ų16.210%0.1048%0.083CC..Hα-helixtrans-75.7-15.6-174.6-59.1-62.3-170.6-73.30112.8S91 R95 I96 A97 N123 T124S91-K93 PolarHBondContact O-N 2.96Å; S91-K93 PolarHBondContact OG-N 3.33Å; S91-K93 VanDerWaalsContact OG-N 3.1Å; K93-R95 PolarHBondContact O-N 3.23Å; K93-I96 HydrophobicContact CB-CG1 4.37Å; K93-I96 HydrophobicContact CD-CD1 3.81Å; K93-I96 HydrophobicContact CD-CG1 4.26Å; K93-I96 VanDerWaalsContact O-CG1 3.23Å; K93-I96 WeakPolarHBondContact O-CG1 3.24Å; K93-I96 PolarHBondContact O-N 3.28Å; K93-I96 VanDerWaalsContact O-N 3.14Å; K93-A97 WeakPolarHBondContact O-CB 3.43Å; K93-A97 PolarHBondContact O-N 3.34Å; K93-N123 HydrophobicContact CB-CB 4.04Å; K93-N123 HydrophobicContact CG-CB 3.65Å; K93-T124 WeakPolarHBondContact CD-OG1 3.16Å
94D98.5Very high96.7Very high0 Ų016.2 Ų16.20%08%0.083CC..Hα-helixtrans-58.2-35.5173.6-53.2-3.4000110.8V58 N87 A88 G89 G90 S91 V92 L98 M130V58-D94 HydrophobicContact CG1-CB 4.07Å; V58-D94 HydrophobicContact CG2-CB 4Å; N87-D94 HydrophobicContact CB-CB 3.95Å; N87-D94 WeakPolarHBondContact CB-OD2 3.41Å; A88-D94 PolarHBondContact N-OD2 2.93Å; G89-D94 WeakPolarHBondContact CA-OD2 3.49Å; G89-D94 PolarHBondContact N-OD2 3.49Å; G90-D94 PolarHBondContact N-OD2 2.73Å; S91-D94 PolarHBondContact N-OD2 2.77Å; S91-D94 WeakPolarHBondContact O-CB 3.39Å; S91-D94 PolarHBondContact O-N 3.5Å; S91-D94 PolarHBondContact OG-OD1 2.97Å; V92-D94 PolarHBondContact O-N 3.1Å; D94-L98 WeakPolarHBondContact O-CB 3.48Å; D94-L98 PolarHBondContact O-N 3.06Å; D94-L98 VanDerWaalsContact O-N 3.08Å; D94-M130 HydrophobicContact CB-CE 4.23Å
95R98.5Very high96.6Very high14 Ų1419.1 Ų19.15%0.05310%0.097CC..Hα-helixtrans-62-46.1176.9-62.6-175.3179.3-100.66.3112.3V58 T61 E84 V92 K93 R99 A205 T210 E213V58-R95 HydrophobicContact CG1-CB 4.36Å; V58-R95 HydrophobicContact CG1-CG 3.87Å; T61-R95 PolarHBondContact OG1-NH2 2.98Å; T61-R95 VanDerWaalsContact OG1-NH2 3.17Å; E84-R95 IonicContact OE1-CZ 2.72Å; E84-R95 IonicContact OE1-NE 3.16Å; E84-R95 PolarHBondContact OE1-NE 3.13Å; E84-R95 IonicContact OE1-NH2 3.06Å; E84-R95 PolarHBondContact OE1-NH2 2.8Å; E84-R95 WeakPolarHBondContact OE2-CD 3.42Å; E84-R95 IonicContact OE2-CZ 2.78Å; E84-R95 IonicContact OE2-NE 2.76Å; E84-R95 PolarHBondContact OE2-NE 3.39Å; E84-R95 IonicContact OE2-NH2 2.96Å; E84-R95 PolarHBondContact OE2-NH2 2.85Å; V92-R95 WeakPolarHBondContact O-CB 3.34Å; V92-R95 PolarHBondContact O-N 2.86Å; K93-R95 PolarHBondContact O-N 3.23Å; R95-R99 WeakPolarHBondContact O-CB 3.2Å; R95-R99 PolarHBondContact O-N 3.15Å; R95-A205 HydrophobicContact CB-CB 4.37Å; R95-T210 WeakPolarHBondContact CD-OG1 3.31Å; R95-T210 PolarHBondContact NE-OG1 2.88Å; R95-E213 IonicContact CZ-OE1 2.65Å; R95-E213 IonicContact CZ-OE2 2.84Å; R95-E213 IonicContact NH1-OE1 2.68Å; R95-E213 PolarHBondContact NH1-OE1 3.46Å; R95-E213 IonicContact NH1-OE2 2.84Å; R95-E213 IonicContact NH2-OE1 3.7Å; R95-E213 PolarHBondContact NH2-OE1 3.48Å; R95-E213 IonicContact NH2-OE2 3.94Å; R95-E213 PolarHBondContact NH2-OE2 3.21Å
96I98Very high96.5Very high0 Ų022.9 Ų22.90%011%0.111CC..Hα-helixtrans-76.1-37.9-176.273.5165.8000110.6K93 L98 R99 M100 T124 Q196 N202 A205 H206K93-I96 HydrophobicContact CB-CG1 4.37Å; K93-I96 HydrophobicContact CD-CD1 3.81Å; K93-I96 HydrophobicContact CD-CG1 4.26Å; K93-I96 VanDerWaalsContact O-CG1 3.23Å; K93-I96 WeakPolarHBondContact O-CG1 3.24Å; K93-I96 PolarHBondContact O-N 3.28Å; K93-I96 VanDerWaalsContact O-N 3.14Å; I96-L98 PolarHBondContact O-N 3.41Å; I96-R99 PolarHBondContact O-N 2.83Å; I96-M100 HydrophobicContact CD1-CE 4.36Å; I96-M100 HydrophobicContact CG1-CE 4.24Å; I96-M100 WeakPolarHBondContact O-CB 3.27Å; I96-M100 WeakPolarHBondContact O-CG 3.23Å; I96-M100 PolarHBondContact O-N 3.5Å; I96-T124 HydrophobicContact CD1-CG2 3.93Å; I96-T124 HydrophobicContact CG1-CG2 4.23Å; I96-Q196 HydrophobicContact CD1-CB 4.12Å; I96-N202 HydrophobicContact CB-CB 4.46Å; I96-N202 HydrophobicContact CD1-CB 4.42Å; I96-N202 HydrophobicContact CG2-CB 4.39Å; I96-N202 WeakPolarHBondContact CG2-O 3.45Å; I96-N202 WeakPolarHBondContact CG2-OD1 3.47Å; I96-A205 HydrophobicContact CG2-CB 4.32Å; I96-H206 WeakPolarHBondContact CG2-NE2 3.41Å
97A98.2Very high96.2Very high0 Ų019 Ų190%010%0.101CC..Hα-helixtrans-58.7-49.6176.300000110.7K93 V101 L128 V131K93-A97 WeakPolarHBondContact O-CB 3.43Å; K93-A97 PolarHBondContact O-N 3.34Å; A97-V101 WeakPolarHBondContact O-CG2 3.37Å; A97-V101 PolarHBondContact O-N 2.8Å; A97-L128 HydrophobicContact CB-CB 4.49Å; A97-L128 HydrophobicContact CB-CD2 3.8Å; A97-L128 HydrophobicContact CB-CG 3.84Å; A97-V131 HydrophobicContact CB-CG2 4.33Å
98L97.9Very high95.9Very high12 Ų1220.9 Ų20.96%0.06312%0.122CC..Hα-helixtrans-61.6-48.5176.5-17859.2000111.5L55 V58 D94 I96 M100 V101 E102 V131L55-L98 HydrophobicContact CB-CD1 4.09Å; L55-L98 HydrophobicContact CB-CD2 4.37Å; L55-L98 HydrophobicContact CD1-CD1 4.01Å; V58-L98 HydrophobicContact CB-CD2 4.11Å; V58-L98 HydrophobicContact CG1-CD2 4.41Å; V58-L98 HydrophobicContact CG2-CD2 4.42Å; D94-L98 WeakPolarHBondContact O-CB 3.48Å; D94-L98 PolarHBondContact O-N 3.06Å; D94-L98 VanDerWaalsContact O-N 3.08Å; I96-L98 PolarHBondContact O-N 3.41Å; L98-M100 PolarHBondContact O-N 2.82Å; L98-V101 PolarHBondContact O-N 2.83Å; L98-E102 HydrophobicContact CD1-CG 3.97Å; L98-E102 HydrophobicContact CG-CG 4.34Å; L98-E102 WeakPolarHBondContact O-CB 3.48Å; L98-E102 WeakPolarHBondContact O-CG 3.34Å; L98-E102 PolarHBondContact O-N 3.4Å; L98-V131 HydrophobicContact CB-CG2 4.32Å; L98-V131 HydrophobicContact CD1-CG2 4.39Å
99R97.2Very high95.7Very high5 Ų520 Ų202%0.01911%0.111CC..Hα-helixtrans-64.7-40.8-177.4-179.455.5173.9-113.2-13.5113.1F39 E41 R95 I96 N103 G201 I204 A205 D208F39-R99 PolarHBondContact O-NH2 3.24Å; E41-R99 IonicContact OE1-CZ 4Å; E41-R99 IonicContact OE1-NE 2.78Å; E41-R99 IonicContact OE1-NH1 3.96Å; E41-R99 PolarHBondContact OE1-NH1 3.04Å; E41-R99 IonicContact OE2-NH1 3.81Å; E41-R99 PolarHBondContact OE2-NH1 3.43Å; R95-R99 WeakPolarHBondContact O-CB 3.2Å; R95-R99 PolarHBondContact O-N 3.15Å; I96-R99 PolarHBondContact O-N 2.83Å; R99-N103 PolarHBondContact NE-OD1 3.32Å; R99-N103 VanDerWaalsContact O-CB 3.23Å; R99-N103 WeakPolarHBondContact O-CB 3.38Å; R99-N103 PolarHBondContact O-N 3.14Å; R99-G201 WeakPolarHBondContact CG-O 3.21Å; R99-I204 HydrophobicContact CG-CG2 4.03Å; R99-A205 HydrophobicContact CB-CB 3.8Å; R99-A205 HydrophobicContact CG-CB 4.02Å; R99-D208 IonicContact CZ-OD2 3.18Å; R99-D208 IonicContact NH1-OD2 3.78Å; R99-D208 PolarHBondContact NH1-OD2 3.19Å; R99-D208 IonicContact NH2-OD2 2.68Å; R99-D208 PolarHBondContact NH2-OD2 3.18Å
100M96.4Very high95.6Very high0 Ų020.2 Ų20.20%011%0.11CC..Hα-helixtrans-63.8-43.4178.6-70.3-174.9-55.400111I96 L98 N103 G104 T124 L128 L194 Q196 N199I96-M100 HydrophobicContact CD1-CE 4.36Å; I96-M100 HydrophobicContact CG1-CE 4.24Å; I96-M100 WeakPolarHBondContact O-CB 3.27Å; I96-M100 WeakPolarHBondContact O-CG 3.23Å; I96-M100 PolarHBondContact O-N 3.5Å; L98-M100 PolarHBondContact O-N 2.82Å; M100-N103 PolarHBondContact O-N 2.95Å; M100-G104 PolarHBondContact O-N 3.46Å; M100-T124 HydrophobicContact CE-CG2 4.15Å; M100-L128 HydrophobicContact CE-CD2 4.48Å; M100-L194 HydrophobicContact CB-CB 4.35Å; M100-L194 HydrophobicContact CB-CD1 4.13Å; M100-L194 HydrophobicContact CE-CB 4.34Å; M100-L194 HydrophobicContact SD-CB 4.29Å; M100-Q196 HydrophobicContact CE-CB 4.45Å; M100-Q196 HydrophobicContact SD-CB 4.46Å; M100-N199 HydrophobicContact CG-CB 4.33Å; M100-N199 HydrophobicContact SD-CB 3.92Å
101V96.7Very high95.5Very high0 Ų025.7 Ų25.70%013%0.129CC..Hα-helixtrans-66.3-48.2176.21730000111.5A97 L98 N103 G104 E105 L110 L116 L128 V131 K135 Y137 L194A97-V101 WeakPolarHBondContact O-CG2 3.37Å; A97-V101 PolarHBondContact O-N 2.8Å; L98-V101 PolarHBondContact O-N 2.83Å; V101-N103 VanDerWaalsContact C-N 3.28Å; V101-N103 PolarHBondContact O-N 2.8Å; V101-G104 PolarHBondContact O-N 3.33Å; V101-G104 VanDerWaalsContact O-N 3.08Å; V101-E105 HydrophobicContact CG1-CG 4.31Å; V101-E105 WeakPolarHBondContact O-CG 3.48Å; V101-E105 PolarHBondContact O-N 3.35Å; V101-L110 HydrophobicContact CB-CD1 4.31Å; V101-L110 HydrophobicContact CG1-CD1 4.12Å; V101-L110 HydrophobicContact CG2-CD1 4.49Å; V101-L110 WeakPolarHBondContact O-CD1 3.43Å; V101-L116 HydrophobicContact CG2-CD1 3.96Å; V101-L128 HydrophobicContact CG2-CD2 3.9Å; V101-V131 HydrophobicContact CB-CG1 3.86Å; V101-V131 HydrophobicContact CG1-CG1 3.8Å; V101-V131 HydrophobicContact CG2-CG1 3.78Å; V101-K135 HydrophobicContact CG1-CD 3.88Å; V101-Y137 HydrophobicContact CG1-CE2 3.88Å; V101-L194 HydrophobicContact CG2-CD1 3.67Å
102E95.4Very high95.4Very high53 Ų5331.4 Ų31.425%0.24817%0.166CC..Hα-helixtrans-62.1-35.6178.5-72.9-179.7156.300112.3L98 R106L98-E102 HydrophobicContact CD1-CG 3.97Å; L98-E102 HydrophobicContact CG-CG 4.34Å; L98-E102 WeakPolarHBondContact O-CB 3.48Å; L98-E102 WeakPolarHBondContact O-CG 3.34Å; L98-E102 PolarHBondContact O-N 3.4Å; E102-R106 VanDerWaalsContact O-CB 3.26Å; E102-R106 WeakPolarHBondContact O-CB 3.49Å; E102-R106 PolarHBondContact O-N 3.17Å
103N93.9Very high95.3Very high19 Ų1934 Ų3410%0.10219%0.193CC..Hα-helixtrans-61.1-47.1171.8-84.1-7.8000111.3R99 M100 V101 R106 A107R99-N103 PolarHBondContact NE-OD1 3.32Å; R99-N103 VanDerWaalsContact O-CB 3.23Å; R99-N103 WeakPolarHBondContact O-CB 3.38Å; R99-N103 PolarHBondContact O-N 3.14Å; M100-N103 PolarHBondContact O-N 2.95Å; V101-N103 VanDerWaalsContact C-N 3.28Å; V101-N103 PolarHBondContact O-N 2.8Å; N103-R106 PolarHBondContact O-N 3.49Å; N103-R106 PolarHBondContact OD1-NH2 3.1Å; N103-A107 VanDerWaalsContact O-CB 3.28Å; N103-A107 WeakPolarHBondContact O-CB 3.42Å; N103-A107 PolarHBondContact O-N 3.05Å
104G93.7Very high95.3Very high0 Ų033.5 Ų33.50%019%0.191CC..Hα-helixtrans-69-36.4-178.800000114.2M100 V101 A107 G108 Y109 L110M100-G104 PolarHBondContact O-N 3.46Å; V101-G104 PolarHBondContact O-N 3.33Å; V101-G104 VanDerWaalsContact O-N 3.08Å; G104-A107 PolarHBondContact O-N 3.24Å; G104-G108 PolarHBondContact O-N 2.88Å; G104-Y109 WeakPolarHBondContact CA-OH 3.39Å; G104-Y109 PolarHBondContact O-N 3.2Å; G104-L110 PolarHBondContact O-N 2.9Å
105E94.9Very high95.3Very high62 Ų6233.9 Ų33.929%0.2919%0.194SC..Hα-helixtrans-63.6-45.9172.5-72.1175.4159.900110.8V101 A107 G108 L110 K135 Y137V101-E105 HydrophobicContact CG1-CG 4.31Å; V101-E105 WeakPolarHBondContact O-CG 3.48Å; V101-E105 PolarHBondContact O-N 3.35Å; E105-A107 VanDerWaalsContact C-N 3.34Å; E105-A107 PolarHBondContact O-N 3.43Å; E105-G108 PolarHBondContact O-N 3.48Å; E105-G108 VanDerWaalsContact O-N 3.17Å; E105-L110 HydrophobicContact CG-CB 4.16Å; E105-K135 VanDerWaalsContact CD-NZ 3.31Å; E105-K135 WeakPolarHBondContact OE1-CD 3.46Å; E105-K135 IonicContact OE1-NZ 2.94Å; E105-K135 PolarHBondContact OE1-NZ 3.37Å; E105-K135 VanDerWaalsContact OE1-NZ 3.11Å; E105-K135 IonicContact OE2-NZ 3.22Å; E105-K135 PolarHBondContact OE2-NZ 3.48Å; E105-Y137 VanDerWaalsContact CG-OH 3.29Å; E105-Y137 WeakPolarHBondContact CG-OH 3.32Å; E105-Y137 PolarHBondContact OE1-OH 3.28Å
106R92.9Very high95.3Very high109 Ų10933.3 Ų33.341%0.41119%0.192SC..Hα-helixtrans-64.7-36.5176.9172.617146.3-122.7-4.6112.7F39 E102 N103 G108F39-R106 VanDerWaalsContact CE1-NH2 3.26Å; E102-R106 VanDerWaalsContact O-CB 3.26Å; E102-R106 WeakPolarHBondContact O-CB 3.49Å; E102-R106 PolarHBondContact O-N 3.17Å; N103-R106 PolarHBondContact O-N 3.49Å; N103-R106 PolarHBondContact OD1-NH2 3.1Å; R106-G108 VanDerWaalsContact C-N 3.28Å
107A90.6Very high95.3Very high41 Ų4133.4 Ų33.434%0.33919%0.192SC..Hα-helixtrans-75.4-17.9176.300000113A10 N103 G104 E105 Y109A10-A107 HydrophobicContact CB-CB 3.62Å; N103-A107 VanDerWaalsContact O-CB 3.28Å; N103-A107 WeakPolarHBondContact O-CB 3.42Å; N103-A107 PolarHBondContact O-N 3.05Å; G104-A107 PolarHBondContact O-N 3.24Å; E105-A107 VanDerWaalsContact C-N 3.34Å; E105-A107 PolarHBondContact O-N 3.43Å; A107-Y109 HydrophobicContact CB-CD1 3.53Å; A107-Y109 HydrophobicContact CB-CE1 3.61Å
108G91.7Very high95.2Very high46 Ų4633.4 Ų33.447%0.47419%0.192SC..THydrogen-bonded Turntrans84.52.8178.600000115.2G104 E105 R106G104-G108 PolarHBondContact O-N 2.88Å; E105-G108 PolarHBondContact O-N 3.48Å; E105-G108 VanDerWaalsContact O-N 3.17Å; R106-G108 VanDerWaalsContact C-N 3.28Å
109Y91.7Very high95Very high23 Ų2333 Ų339%0.0919%0.19CC..  trans-84.2-19.2176.465.2-112.6000113.3V14 L15 G104 A107 M114 I192 L194V14-Y109 HydrophobicContact CG2-CD1 4.42Å; V14-Y109 HydrophobicContact CG2-CD2 4.25Å; V14-Y109 HydrophobicContact CG2-CE1 3.82Å; V14-Y109 HydrophobicContact CG2-CE2 3.66Å; L15-Y109 HydrophobicContact CD2-CD1 4.19Å; L15-Y109 HydrophobicContact CD2-CG 3.94Å; G104-Y109 WeakPolarHBondContact CA-OH 3.39Å; G104-Y109 PolarHBondContact O-N 3.2Å; A107-Y109 HydrophobicContact CB-CD1 3.53Å; A107-Y109 HydrophobicContact CB-CE1 3.61Å; Y109-M114 VanDerWaalsContact O-SD 3.36Å; Y109-I192 HydrophobicContact CD2-CD1 3.45Å; Y109-I192 VanDerWaalsContact CD2-CD1 3.45Å; Y109-I192 HydrophobicContact CE2-CD1 3.71Å; Y109-I192 HydrophobicContact CG-CD1 4.47Å; Y109-L194 HydrophobicContact CE2-CD2 4.42Å
110L94.8Very high94.5Very high8 Ų832.8 Ų32.84%0.04219%0.189CC..  trans-95.1127.3166.4-73.2174.7000110.2V101 G104 E105 L116 I192 L194V101-L110 HydrophobicContact CB-CD1 4.31Å; V101-L110 HydrophobicContact CG1-CD1 4.12Å; V101-L110 HydrophobicContact CG2-CD1 4.49Å; V101-L110 WeakPolarHBondContact O-CD1 3.43Å; G104-L110 PolarHBondContact O-N 2.9Å; E105-L110 HydrophobicContact CG-CB 4.16Å; L110-L116 HydrophobicContact CD2-CD2 3.64Å; L110-I192 HydrophobicContact CD2-CG2 3.53Å; L110-L194 HydrophobicContact CD1-CD2 4.13Å
111R94.1Very high93.3Very high122 Ų12233.5 Ų33.546%0.4619%0.194SC..  trans-122.9148.7178.8-60.7-175.8-63.7-78.91.5110G113 M114 Y137 D190R111-G113 PolarHBondContact O-N 3.09Å; R111-M114 HydrophobicContact CB-CG 4.14Å; R111-M114 HydrophobicContact CB-SD 3.88Å; R111-M114 HydrophobicContact CG-SD 4.26Å; R111-M114 PolarHBondContact N-SD 2.96Å; R111-M114 WeakPolarHBondContact O-CB 3.22Å; R111-M114 VanDerWaalsContact O-CG 3.23Å; R111-M114 WeakPolarHBondContact O-CG 3.29Å; R111-M114 PolarHBondContact O-N 3.09Å; R111-M114 VanDerWaalsContact O-N 3.16Å; R111-Y137 VanDerWaalsContact O-CE1 3.27Å; R111-Y137 WeakPolarHBondContact O-CE1 3.47Å; R111-D190 IonicContact NH2-OD1 2.81Å; R111-D190 PolarHBondContact NH2-OD1 2.89Å
112P94.7Very high92.6Very high121 Ų12133.5 Ų33.579%0.78619%0.194SC*.THydrogen-bonded Turntrans-50134.7176.6-27.335000112.4
113G94.4Very high92.5Very high56 Ų5631.4 Ų31.458%0.57719%0.185SC*.THydrogen-bonded Turntrans84.5-3179.600000116R111R111-G113 PolarHBondContact O-N 3.09Å
114M98Very high92.6Very high12 Ų1230.5 Ų30.56%0.05918%0.18CC..PPolyproline II helixtrans-62.4163.4173-75.3-176.270.300112.6Y109 R111 Y137 R138 D190 I192Y109-M114 VanDerWaalsContact O-SD 3.36Å; R111-M114 HydrophobicContact CB-CG 4.14Å; R111-M114 HydrophobicContact CB-SD 3.88Å; R111-M114 HydrophobicContact CG-SD 4.26Å; R111-M114 PolarHBondContact N-SD 2.96Å; R111-M114 WeakPolarHBondContact O-CB 3.22Å; R111-M114 VanDerWaalsContact O-CG 3.23Å; R111-M114 WeakPolarHBondContact O-CG 3.29Å; R111-M114 PolarHBondContact O-N 3.09Å; R111-M114 VanDerWaalsContact O-N 3.16Å; M114-Y137 HydrophobicContact CB-CD1 4.17Å; M114-Y137 HydrophobicContact CB-CE1 4.35Å; M114-R138 PolarHBondContact O-N 3.11Å; M114-R138 VanDerWaalsContact O-N 3.13Å; M114-D190 WeakPolarHBondContact CA-O 3.3Å; M114-D190 WeakPolarHBondContact CB-O 3.25Å; M114-D190 HydrophobicContact CG-CB 4.23Å; M114-I192 HydrophobicContact CE-CB 4.28Å; M114-I192 HydrophobicContact CE-CG2 4.21Å
115T98.3Very high92.8Very high9 Ų930.5 Ų30.56%0.05518%0.18CC..EExtended strand (participates in β ladder)trans-100.9123176.3-56.50000110.9I117 R138 I140 I188 D190 A191 I192T115-I117 HydrophobicContact CG2-CG1 4.05Å; T115-R138 CarbonylContact C-O 3.51Å; T115-R138 WeakPolarHBondContact CA-O 3.49Å; T115-R138 HydrophobicContact CG2-CB 4.14Å; T115-R138 HydrophobicContact CG2-CG 4.03Å; T115-I140 HydrophobicContact CG2-CD1 3.77Å; T115-I140 HydrophobicContact CG2-CG1 3.94Å; T115-I188 HydrophobicContact CG2-CG2 4.42Å; T115-D190 PolarHBondContact N-O 3.47Å; T115-A191 HydrophobicContact CG2-CB 4.48Å; T115-A191 CarbonylContact O-C 3.55Å; T115-A191 VanDerWaalsContact O-CA 3.28Å; T115-A191 WeakPolarHBondContact O-CA 3.34Å; T115-I192 PolarHBondContact O-N 3.19Å
116L98Very high92.9Very high2 Ų227.7 Ų27.71%0.0117%0.167CC..EExtended strand (participates in β ladder)trans-90.6124171.4-56-177.8000109.4V101 L110 A132 Y137 R138 C139 I140 I192 L194V101-L116 HydrophobicContact CG2-CD1 3.96Å; L110-L116 HydrophobicContact CD2-CD2 3.64Å; L116-A132 HydrophobicContact CD1-CB 4.35Å; L116-Y137 HydrophobicContact CD1-CD2 4.16Å; L116-Y137 HydrophobicContact CD1-CG 4.12Å; L116-Y137 HydrophobicContact CG-CG 4.18Å; L116-R138 PolarHBondContact N-O 3.06Å; L116-C139 CarbonylContact O-C 3.5Å; L116-C139 WeakPolarHBondContact O-CA 3.45Å; L116-I140 PolarHBondContact O-N 2.93Å; L116-I192 HydrophobicContact CD2-CG2 3.9Å; L116-L194 HydrophobicContact CD2-CD1 4.23Å; L116-L194 HydrophobicContact CD2-CG 4.45Å
117I97.4Very high93.1Very high1 Ų122.5 Ų22.51%0.00515%0.147CC..EExtended strand (participates in β ladder)trans-117.2130.4174.7-53-175.5000108.1T115 I140 V142 A181 L184 C185 I188 A191 I192 I193T115-I117 HydrophobicContact CG2-CG1 4.05Å; I117-I140 VanDerWaalsContact CA-O 3.32Å; I117-I140 WeakPolarHBondContact CA-O 3.18Å; I117-I140 HydrophobicContact CD1-CD1 4.42Å; I117-I140 HydrophobicContact CG1-CB 4.22Å; I117-I140 HydrophobicContact CG1-CD1 4.38Å; I117-V142 HydrophobicContact CG2-CG2 4.18Å; I117-A181 HydrophobicContact CG2-CB 4.02Å; I117-L184 HydrophobicContact CD1-CB 3.95Å; I117-C185 HydrophobicContact CD1-CB 4.08Å; I117-I188 HydrophobicContact CD1-CD1 4.15Å; I117-A191 HydrophobicContact CD1-CB 3.74Å; I117-A191 HydrophobicContact CG1-CB 4.25Å; I117-I192 PolarHBondContact N-O 3Å; I117-I193 HydrophobicContact CB-CG1 4.14Å; I117-I193 HydrophobicContact CG2-CG1 4.38Å; I117-I193 VanDerWaalsContact O-CA 3.28Å; I117-I193 WeakPolarHBondContact O-CA 3.36Å
118E97Very high93.5Very high1 Ų120.6 Ų20.61%0.00513%0.131CC..EExtended strand (participates in β ladder)trans-138.9125.9178.7-169.972.8179.400112.9T124 L128 I140 I141 V142 L194 D195 Q196E118-T124 HydrophobicContact CG-CG2 4.37Å; E118-L128 HydrophobicContact CB-CD1 3.51Å; E118-L128 HydrophobicContact CG-CD1 3.57Å; E118-I140 PolarHBondContact N-O 2.76Å; E118-I140 VanDerWaalsContact N-O 3.12Å; E118-I141 HydrophobicContact CB-CD1 4.26Å; E118-V142 PolarHBondContact O-N 2.79Å; E118-V142 VanDerWaalsContact O-N 3.07Å; E118-L194 PolarHBondContact OE2-N 2.69Å; E118-D195 PolarHBondContact OE2-N 3.33Å; E118-Q196 WeakPolarHBondContact OE1-CB 3.18Å; E118-Q196 WeakPolarHBondContact OE1-CG 3.15Å; E118-Q196 PolarHBondContact OE1-N 2.79Å
119P92.6Very high93.8Very high4 Ų418.4 Ų18.43%0.02611%0.109CC..EExtended strand (participates in β ladder)trans-75.6119.4165.729.8-30.9000110.4V142 I178 A181 Q196 Y197P119-V142 WeakPolarHBondContact CA-O 3.42Å; P119-I178 HydrophobicContact CB-CG1 4.24Å; P119-A181 HydrophobicContact CB-CB 4.02Å; P119-A181 HydrophobicContact CG-CB 4.12Å; P119-Q196 PolarHBondContact O-NE2 3.36Å; P119-Y197 HydrophobicContact CG-CE2 4.15Å
120T86.7Confident94.1Very high0 Ų017.9 Ų17.90%011%0.108CC..  trans-156.3153.2-172-174.50000115.8G122 T124 I141 V142 M143 Q196T120-G122 PolarHBondContact O-N 3.48Å; T120-G122 PolarHBondContact OG1-N 3.06Å; T120-T124 WeakPolarHBondContact OG1-CB 3.33Å; T120-I141 HydrophobicContact CG2-CG2 3.55Å; T120-V142 PolarHBondContact N-O 2.94Å; T120-M143 WeakPolarHBondContact O-CB 3.18Å; T120-Q196 PolarHBondContact OG1-NE2 2.7Å
121S71.3Confident94.3Very high15 Ų1517.5 Ų17.511%0.10511%0.106CC..SBendtrans-77.110168.659.10000114.3K151S121-K151 PolarHBondContact O-NZ 2.94Å
122G82.7Confident94.5Very high0 Ų011.8 Ų11.80%09%0.085CC..SBendtrans113.3-47.2165.500000114.7T120 T124 G125 I126T120-G122 PolarHBondContact O-N 3.48Å; T120-G122 PolarHBondContact OG1-N 3.06Å; G122-T124 PolarHBondContact O-N 3.19Å; G122-G125 CarbonylContact O-C 3.59Å; G122-G125 WeakPolarHBondContact O-CA 3.38Å; G122-G125 PolarHBondContact O-N 3.49Å; G122-I126 PolarHBondContact O-N 3.11Å
123N93.6Very high94.7Very high9 Ų99.1 Ų9.15%0.0487%0.072CC..Hα-helixtrans-65.8-39.4-176.1-79.6-29000113.2K93 G125 I126 G127 D366 N370K93-N123 HydrophobicContact CB-CB 4.04Å; K93-N123 HydrophobicContact CG-CB 3.65Å; N123-G125 PolarHBondContact O-N 3.35Å; N123-I126 PolarHBondContact O-N 2.9Å; N123-G127 PolarHBondContact O-N 3.09Å; N123-D366 PolarHBondContact ND2-OD2 3.32Å; N123-N370 PolarHBondContact OD1-ND2 2.86Å
124T95.9Very high94.9Very high0 Ų09.2 Ų9.20%06%0.062CC..Hα-helixtrans-64.3-35.8172.1-45.90000110.7K93 I96 M100 E118 T120 G122 G127 L128 Q196K93-T124 WeakPolarHBondContact CD-OG1 3.16Å; I96-T124 HydrophobicContact CD1-CG2 3.93Å; I96-T124 HydrophobicContact CG1-CG2 4.23Å; M100-T124 HydrophobicContact CE-CG2 4.15Å; E118-T124 HydrophobicContact CG-CG2 4.37Å; T120-T124 WeakPolarHBondContact OG1-CB 3.33Å; G122-T124 PolarHBondContact O-N 3.19Å; T124-G127 PolarHBondContact O-N 2.85Å; T124-L128 HydrophobicContact CG2-CD1 4.18Å; T124-L128 HydrophobicContact CG2-CG 4.47Å; T124-L128 WeakPolarHBondContact O-CB 3.27Å; T124-L128 WeakPolarHBondContact O-CG 3.47Å; T124-L128 PolarHBondContact O-N 3.21Å; T124-Q196 HydrophobicContact CG2-CB 4.34Å; T124-Q196 PolarHBondContact OG1-OE1 3.14Å
125G96.5Very high94.9Very high0 Ų011.9 Ų11.90%07%0.073CC..Hα-helixtrans-62.6-44.7173.800000112.8G122 N123 L128 A129 I141G122-G125 CarbonylContact O-C 3.59Å; G122-G125 WeakPolarHBondContact O-CA 3.38Å; G122-G125 PolarHBondContact O-N 3.49Å; N123-G125 PolarHBondContact O-N 3.35Å; G125-L128 PolarHBondContact O-N 2.84Å; G125-A129 WeakPolarHBondContact O-CB 3.28Å; G125-A129 PolarHBondContact O-N 2.79Å; G125-I141 VanDerWaalsContact CA-CD1 3.45Å
126I97.3Very high94.8Very high2 Ų213.8 Ų13.81%0.0110%0.095CC..Hα-helixtrans-61.7-45.7175.6-67.9171.7000110.4G122 N123 L128 A129 M130 K151 V154 L155 L158G122-I126 PolarHBondContact O-N 3.11Å; N123-I126 PolarHBondContact O-N 2.9Å; I126-L128 PolarHBondContact O-N 3.04Å; I126-A129 PolarHBondContact O-N 3.33Å; I126-M130 WeakPolarHBondContact O-CB 3.44Å; I126-M130 PolarHBondContact O-N 3.21Å; I126-K151 HydrophobicContact CD1-CB 4.45Å; I126-K151 HydrophobicContact CD1-CG 4.13Å; I126-V154 HydrophobicContact CD1-CB 4.27Å; I126-V154 HydrophobicContact CD1-CG1 3.97Å; I126-V154 HydrophobicContact CG1-CG1 3.99Å; I126-V154 HydrophobicContact CG2-CG1 3.91Å; I126-L155 HydrophobicContact CG1-CD2 4Å; I126-L155 HydrophobicContact CG1-CG 4.07Å; I126-L158 HydrophobicContact CG2-CD1 4.1Å
127G98.2Very high94.9Very high0 Ų014.7 Ų14.70%010%0.098CC..Hα-helixtrans-59.1-46.4176.500000112.3N123 T124 M130 V131N123-G127 PolarHBondContact O-N 3.09Å; T124-G127 PolarHBondContact O-N 2.85Å; G127-M130 PolarHBondContact O-N 3.4Å; G127-V131 VanDerWaalsContact O-CG2 3.23Å; G127-V131 WeakPolarHBondContact O-CG2 3.43Å; G127-V131 PolarHBondContact O-N 3.3Å
128L98.2Very high94.9Very high1 Ų119.7 Ų19.71%0.00512%0.117CC..Hα-helixtrans-68.8-40.9178.9-75.9174.4000112.5A97 M100 V101 E118 T124 G125 I126 M130 V131 A132 L194A97-L128 HydrophobicContact CB-CB 4.49Å; A97-L128 HydrophobicContact CB-CD2 3.8Å; A97-L128 HydrophobicContact CB-CG 3.84Å; M100-L128 HydrophobicContact CE-CD2 4.48Å; V101-L128 HydrophobicContact CG2-CD2 3.9Å; E118-L128 HydrophobicContact CB-CD1 3.51Å; E118-L128 HydrophobicContact CG-CD1 3.57Å; T124-L128 HydrophobicContact CG2-CD1 4.18Å; T124-L128 HydrophobicContact CG2-CG 4.47Å; T124-L128 WeakPolarHBondContact O-CB 3.27Å; T124-L128 WeakPolarHBondContact O-CG 3.47Å; T124-L128 PolarHBondContact O-N 3.21Å; G125-L128 PolarHBondContact O-N 2.84Å; I126-L128 PolarHBondContact O-N 3.04Å; L128-M130 VanDerWaalsContact C-N 3.32Å; L128-M130 PolarHBondContact O-N 2.96Å; L128-V131 PolarHBondContact O-N 3.35Å; L128-A132 VanDerWaalsContact O-CB 3.22Å; L128-A132 WeakPolarHBondContact O-CB 3.3Å; L128-A132 PolarHBondContact O-N 3.24Å; L128-L194 HydrophobicContact CD1-CD1 4.4Å; L128-L194 HydrophobicContact CD2-CD1 3.51Å
129A98.4Very high95Very high1 Ų120 Ų201%0.00812%0.119CC..Hα-helixtrans-61.4-40.7175.100000111.5G125 I126 A132 A133 L155 L158 A160G125-A129 WeakPolarHBondContact O-CB 3.28Å; G125-A129 PolarHBondContact O-N 2.79Å; I126-A129 PolarHBondContact O-N 3.33Å; A129-A132 PolarHBondContact O-N 2.99Å; A129-A133 WeakPolarHBondContact O-CB 3.2Å; A129-A133 PolarHBondContact O-N 2.73Å; A129-L155 HydrophobicContact CB-CD2 3.86Å; A129-L158 HydrophobicContact CB-CB 3.9Å; A129-L158 HydrophobicContact CB-CD1 3.91Å; A129-A160 HydrophobicContact CB-CB 3.83Å
130M98.6Very high95.2Very high12 Ų1220 Ų206%0.05912%0.119CC..Hα-helixtrans-62.4-46.1173.2178.2-175.365.200111.8V54 L55 V58 A88 D94 I126 G127 L128 A132 A133 V134 L158V54-M130 HydrophobicContact CG1-CG 4.33Å; V54-M130 HydrophobicContact CG1-SD 4.34Å; L55-M130 HydrophobicContact CD2-CE 4.03Å; L55-M130 HydrophobicContact CD2-CG 4.17Å; V58-M130 HydrophobicContact CG2-CE 4.13Å; A88-M130 HydrophobicContact CB-CE 4.06Å; A88-M130 HydrophobicContact CB-SD 3.63Å; D94-M130 HydrophobicContact CB-CE 4.23Å; I126-M130 WeakPolarHBondContact O-CB 3.44Å; I126-M130 PolarHBondContact O-N 3.21Å; G127-M130 PolarHBondContact O-N 3.4Å; L128-M130 VanDerWaalsContact C-N 3.32Å; L128-M130 PolarHBondContact O-N 2.96Å; M130-A132 VanDerWaalsContact C-N 3.33Å; M130-A133 PolarHBondContact O-N 2.56Å; M130-V134 WeakPolarHBondContact O-CG2 3.42Å; M130-V134 PolarHBondContact O-N 3.43Å; M130-L158 HydrophobicContact CB-CD1 4.38Å; M130-L158 HydrophobicContact CB-CD2 4.4Å
131V98.5Very high95.8Very high0 Ų020 Ų200%012%0.119CC..Hα-helixtrans-62.9-42.1177.2176.10000110.8L55 A97 L98 V101 G127 L128 V134 K135L55-V131 HydrophobicContact CD1-CG1 4.41Å; L55-V131 HydrophobicContact CD2-CB 4.45Å; L55-V131 HydrophobicContact CD2-CG2 3.86Å; A97-V131 HydrophobicContact CB-CG2 4.33Å; L98-V131 HydrophobicContact CB-CG2 4.32Å; L98-V131 HydrophobicContact CD1-CG2 4.39Å; V101-V131 HydrophobicContact CB-CG1 3.86Å; V101-V131 HydrophobicContact CG1-CG1 3.8Å; V101-V131 HydrophobicContact CG2-CG1 3.78Å; G127-V131 VanDerWaalsContact O-CG2 3.23Å; G127-V131 WeakPolarHBondContact O-CG2 3.43Å; G127-V131 PolarHBondContact O-N 3.3Å; L128-V131 PolarHBondContact O-N 3.35Å; V131-V134 PolarHBondContact O-N 3.49Å; V131-K135 HydrophobicContact CG1-CD 3.74Å; V131-K135 WeakPolarHBondContact O-CB 3.39Å; V131-K135 PolarHBondContact O-N 3.02Å
132A98.5Very high96.9Very high2 Ų219.3 Ų19.32%0.01711%0.114CC..Hα-helixtrans-62.8-46177.800000112.3L116 L128 A129 M130 V134 K135 G136 Y137 C139L116-A132 HydrophobicContact CD1-CB 4.35Å; L128-A132 VanDerWaalsContact O-CB 3.22Å; L128-A132 WeakPolarHBondContact O-CB 3.3Å; L128-A132 PolarHBondContact O-N 3.24Å; A129-A132 PolarHBondContact O-N 2.99Å; M130-A132 VanDerWaalsContact C-N 3.33Å; A132-V134 VanDerWaalsContact C-N 3.28Å; A132-V134 PolarHBondContact O-N 2.82Å; A132-K135 PolarHBondContact O-N 3.22Å; A132-G136 WeakPolarHBondContact O-CA 3.29Å; A132-G136 PolarHBondContact O-N 3.09Å; A132-Y137 PolarHBondContact O-N 3.41Å; A132-C139 HydrophobicContact CB-CB 3.71Å
133A98.4Very high97.2Very high64 Ų6419.3 Ų19.353%0.52911%0.114SC..Hα-helixtrans-59.7-37.7176.900000112.4A129 M130A129-A133 WeakPolarHBondContact O-CB 3.2Å; A129-A133 PolarHBondContact O-N 2.73Å; M130-A133 PolarHBondContact O-N 2.56Å
134V98.2Very high96.8Very high58 Ų5819.4 Ų19.435%0.35212%0.115SC..Hα-helixtrans-78.7-37.2179.5174.80000112.5N53 V54 L55 M130 V131 A132N53-V134 HydrophobicContact CB-CG1 4.03Å; V54-V134 HydrophobicContact CG1-CG2 3.79Å; L55-V134 HydrophobicContact CD1-CB 3.97Å; L55-V134 HydrophobicContact CD1-CG1 3.74Å; L55-V134 HydrophobicContact CD2-CB 4.42Å; L55-V134 HydrophobicContact CD2-CG2 4.2Å; L55-V134 HydrophobicContact CG-CB 4.14Å; L55-V134 HydrophobicContact CG-CG1 3.95Å; L55-V134 HydrophobicContact CG-CG2 4.2Å; M130-V134 WeakPolarHBondContact O-CG2 3.42Å; M130-V134 PolarHBondContact O-N 3.43Å; V131-V134 PolarHBondContact O-N 3.49Å; A132-V134 VanDerWaalsContact C-N 3.28Å; A132-V134 PolarHBondContact O-N 2.82Å
135K98Very high96.1Very high68 Ų6824.6 Ų24.630%0.29614%0.139SC..Hα-helixtrans-97.5-5.2-173.8-71.9173.9167.5-83.90114.4L55 V101 E105 V131 A132 Y137L55-K135 HydrophobicContact CD1-CD 4.27Å; L55-K135 HydrophobicContact CD1-CG 4.23Å; V101-K135 HydrophobicContact CG1-CD 3.88Å; E105-K135 VanDerWaalsContact CD-NZ 3.31Å; E105-K135 WeakPolarHBondContact OE1-CD 3.46Å; E105-K135 IonicContact OE1-NZ 2.94Å; E105-K135 PolarHBondContact OE1-NZ 3.37Å; E105-K135 VanDerWaalsContact OE1-NZ 3.11Å; E105-K135 IonicContact OE2-NZ 3.22Å; E105-K135 PolarHBondContact OE2-NZ 3.48Å; V131-K135 HydrophobicContact CG1-CD 3.74Å; V131-K135 WeakPolarHBondContact O-CB 3.39Å; V131-K135 PolarHBondContact O-N 3.02Å; A132-K135 PolarHBondContact O-N 3.22Å; K135-Y137 HydrophobicContact CB-CD2 3.75Å; K135-Y137 HydrophobicContact CB-CE2 3.59Å; K135-Y137 HydrophobicContact CD-CE2 4.1Å; K135-Y137 HydrophobicContact CG-CE2 4.5Å
136G97.4Very high95Very high50 Ų5027.4 Ų27.452%0.51515%0.151SC..THydrogen-bonded Turntrans7838.7177.700000113.9A132A132-G136 WeakPolarHBondContact O-CA 3.29Å; A132-G136 PolarHBondContact O-N 3.09Å
137Y98.5Very high93.9Very high20 Ų2027.9 Ų27.98%0.07815%0.154CC..  trans-97.2148.8168.7-62.3-76.2000110.4V101 E105 R111 M114 L116 A132 K135V101-Y137 HydrophobicContact CG1-CE2 3.88Å; E105-Y137 VanDerWaalsContact CG-OH 3.29Å; E105-Y137 WeakPolarHBondContact CG-OH 3.32Å; E105-Y137 PolarHBondContact OE1-OH 3.28Å; R111-Y137 VanDerWaalsContact O-CE1 3.27Å; R111-Y137 WeakPolarHBondContact O-CE1 3.47Å; M114-Y137 HydrophobicContact CB-CD1 4.17Å; M114-Y137 HydrophobicContact CB-CE1 4.35Å; L116-Y137 HydrophobicContact CD1-CD2 4.16Å; L116-Y137 HydrophobicContact CD1-CG 4.12Å; L116-Y137 HydrophobicContact CG-CG 4.18Å; A132-Y137 PolarHBondContact O-N 3.41Å; K135-Y137 HydrophobicContact CB-CD2 3.75Å; K135-Y137 HydrophobicContact CB-CE2 3.59Å; K135-Y137 HydrophobicContact CD-CE2 4.1Å; K135-Y137 HydrophobicContact CG-CE2 4.5Å
138R98.3Very high93Very high107 Ų10728 Ų2840%0.40416%0.155SC..EExtended strand (participates in β ladder)trans-73.9142.2162.5-176.6-179.6177.7-157.6-1.7108.4M114 T115 L116 E161M114-R138 PolarHBondContact O-N 3.11Å; M114-R138 VanDerWaalsContact O-N 3.13Å; T115-R138 CarbonylContact C-O 3.51Å; T115-R138 WeakPolarHBondContact CA-O 3.49Å; T115-R138 HydrophobicContact CG2-CB 4.14Å; T115-R138 HydrophobicContact CG2-CG 4.03Å; L116-R138 PolarHBondContact N-O 3.06Å; R138-E161 IonicContact CZ-OE1 3.4Å; R138-E161 VanDerWaalsContact CZ-OE1 3.22Å; R138-E161 IonicContact CZ-OE2 2.86Å; R138-E161 IonicContact NE-OE1 3.69Å; R138-E161 PolarHBondContact NE-OE1 3.33Å; R138-E161 IonicContact NE-OE2 3.19Å; R138-E161 VanDerWaalsContact NH2-CD 3.26Å; R138-E161 IonicContact NH2-OE1 2.93Å; R138-E161 PolarHBondContact NH2-OE1 3.33Å; R138-E161 IonicContact NH2-OE2 2.69Å; R138-E161 PolarHBondContact NH2-OE2 2.95Å
139C98.5Very high92.4Very high6 Ų633.3 Ų33.34%0.04118%0.179CC..EExtended strand (participates in β ladder)trans-130.3126.7-177.7-169.90000111.5L116 A132 A160 E161L116-C139 CarbonylContact O-C 3.5Å; L116-C139 WeakPolarHBondContact O-CA 3.45Å; A132-C139 HydrophobicContact CB-CB 3.71Å; C139-A160 HydrophobicContact CB-CB 4.28Å; C139-A160 WeakPolarHBondContact O-CA 3.26Å; C139-E161 PolarHBondContact O-N 3.14Å
140I98.1Very high92Very high5 Ų534.5 Ų34.53%0.02619%0.185CC..EExtended strand (participates in β ladder)trans-122.7119.4176.7-51.8179000108.4T115 L116 I117 E118 E161 V163 L184 I188T115-I140 HydrophobicContact CG2-CD1 3.77Å; T115-I140 HydrophobicContact CG2-CG1 3.94Å; L116-I140 PolarHBondContact O-N 2.93Å; I117-I140 VanDerWaalsContact CA-O 3.32Å; I117-I140 WeakPolarHBondContact CA-O 3.18Å; I117-I140 HydrophobicContact CD1-CD1 4.42Å; I117-I140 HydrophobicContact CG1-CB 4.22Å; I117-I140 HydrophobicContact CG1-CD1 4.38Å; E118-I140 PolarHBondContact N-O 2.76Å; E118-I140 VanDerWaalsContact N-O 3.12Å; I140-E161 CarbonylContact C-O 3.45Å; I140-E161 WeakPolarHBondContact CA-O 3.43Å; I140-E161 HydrophobicContact CG1-CB 4.21Å; I140-E161 HydrophobicContact CG2-CB 4.44Å; I140-V163 HydrophobicContact CG2-CG2 4.12Å; I140-L184 HydrophobicContact CG2-CD1 4.38Å; I140-I188 HydrophobicContact CD1-CD1 3.34Å
141I97.9Very high91.6Very high0 Ų034 Ų340%018%0.182CC..EExtended strand (participates in β ladder)trans-106.3122-179.8-60.7-50.9000109.8E118 T120 G125 M143 L155 A160 E161 I162 V163E118-I141 HydrophobicContact CB-CD1 4.26Å; T120-I141 HydrophobicContact CG2-CG2 3.55Å; G125-I141 VanDerWaalsContact CA-CD1 3.45Å; I141-M143 HydrophobicContact CG2-CE 3.89Å; I141-L155 HydrophobicContact CB-CD1 4.24Å; I141-L155 HydrophobicContact CG1-CD1 4.41Å; I141-L155 HydrophobicContact CG1-CD2 3.83Å; I141-L155 HydrophobicContact CG2-CD1 3.92Å; I141-A160 HydrophobicContact CG1-CB 4.26Å; I141-E161 PolarHBondContact N-O 2.97Å; I141-I162 WeakPolarHBondContact O-CA 3.37Å; I141-V163 PolarHBondContact O-N 3.38Å
142V95.4Very high91.2Very high0 Ų034.4 Ų34.40%019%0.185CC..EExtended strand (participates in β ladder)trans-102.6116.6176-168.20000108.5I117 E118 P119 T120 V163 T165 H177 V180 A181 L184I117-V142 HydrophobicContact CG2-CG2 4.18Å; E118-V142 PolarHBondContact O-N 2.79Å; E118-V142 VanDerWaalsContact O-N 3.07Å; P119-V142 WeakPolarHBondContact CA-O 3.42Å; T120-V142 PolarHBondContact N-O 2.94Å; V142-V163 WeakPolarHBondContact CA-O 3.4Å; V142-V163 HydrophobicContact CG1-CB 4.39Å; V142-V163 HydrophobicContact CG1-CG1 4.41Å; V142-V163 HydrophobicContact CG2-CB 4.31Å; V142-T165 HydrophobicContact CG1-CG2 3.77Å; V142-H177 HydrophobicContact CG1-CB 3.94Å; V142-H177 WeakPolarHBondContact CG1-O 3.02Å; V142-V180 HydrophobicContact CG1-CB 4.02Å; V142-V180 HydrophobicContact CG1-CG1 3.82Å; V142-A181 HydrophobicContact CB-CB 4.19Å; V142-A181 HydrophobicContact CG2-CB 3.85Å; V142-L184 HydrophobicContact CG2-CD1 3.83Å
143M89.4Confident91Very high0 Ų039.1 Ų39.10%021%0.207CC..EExtended strand (participates in β ladder)trans-140146.9-174.458.6167.84300113.3T120 I141 M147 V152 L155 I162 V163 R164 T165T120-M143 WeakPolarHBondContact O-CB 3.18Å; I141-M143 HydrophobicContact CG2-CE 3.89Å; M143-M147 HydrophobicContact CB-CG 4.19Å; M143-M147 HydrophobicContact CE-CB 4.35Å; M143-M147 HydrophobicContact SD-CB 3.92Å; M143-M147 HydrophobicContact SD-CG 4.45Å; M143-V152 HydrophobicContact SD-CG2 4.28Å; M143-L155 HydrophobicContact CE-CD1 3.39Å; M143-L155 HydrophobicContact SD-CD1 4.3Å; M143-I162 HydrophobicContact CG-CG2 4.17Å; M143-I162 HydrophobicContact SD-CG2 4.27Å; M143-V163 PolarHBondContact N-O 3.42Å; M143-R164 CarbonylContact O-C 3.58Å; M143-R164 VanDerWaalsContact O-CA 3.28Å; M143-R164 WeakPolarHBondContact O-CA 3.1Å; M143-R164 PolarHBondContact SD-NH1 2.87Å; M143-R164 VanDerWaalsContact SD-NH1 3.38Å; M143-T165 PolarHBondContact O-N 2.83Å
144P83.7Confident90.9Very high12 Ų1237.5 Ų37.58%0.07819%0.19CC..EExtended strand (participates in β ladder)trans-61.4150.7172.9-23.234.1000113K146 M147 T165 N167P144-K146 HydrophobicContact CB-CG 4.21Å; P144-K146 PolarHBondContact O-N 3.5Å; P144-K146 VanDerWaalsContact O-N 3.13Å; P144-M147 HydrophobicContact CB-CE 4.31Å; P144-M147 HydrophobicContact CG-CE 4.05Å; P144-M147 WeakPolarHBondContact O-CG 3.24Å; P144-M147 PolarHBondContact O-N 2.65Å; P144-T165 CarbonylContact C-O 3.53Å; P144-T165 WeakPolarHBondContact CA-O 3.46Å; P144-N167 VanDerWaalsContact CB-OD1 3.28Å; P144-N167 WeakPolarHBondContact CB-OD1 2.8Å
145E81.8Confident90.8Very high108 Ų10834.8 Ų34.851%0.50517%0.173SC..THydrogen-bonded Turntrans-58.2-25.2178.1-76.7175.4171.500114.4M147 R164 T165 N167E145-M147 PolarHBondContact O-N 3.38Å; E145-R164 HydrophobicContact CG-CB 4.07Å; E145-R164 PolarHBondContact O-NH2 3.48Å; E145-T165 PolarHBondContact N-O 2.77Å; E145-N167 PolarHBondContact N-OD1 2.78Å; E145-N167 VanDerWaalsContact N-OD1 3.14Å
146K73Confident90.7Very high59 Ų5936.9 Ų36.926%0.25718%0.183SC..THydrogen-bonded Turntrans-67.1-18.4177.674.2176.5-176.5178.40111.4P144 N167 F272 T335P144-K146 HydrophobicContact CB-CG 4.21Å; P144-K146 PolarHBondContact O-N 3.5Å; P144-K146 VanDerWaalsContact O-N 3.13Å; K146-N167 VanDerWaalsContact CB-OD1 3.22Å; K146-N167 WeakPolarHBondContact CB-OD1 3.1Å; K146-N167 WeakPolarHBondContact CG-OD1 3.26Å; K146-N167 VanDerWaalsContact N-CG 3.32Å; K146-N167 PolarHBondContact N-ND2 3.44Å; K146-N167 VanDerWaalsContact N-ND2 3.18Å; K146-N167 PolarHBondContact N-OD1 2.7Å; K146-F272 HydrophobicContact CD-CE2 4.47Å; K146-T335 HydrophobicContact CB-CG2 3.59Å; K146-T335 HydrophobicContact CD-CG2 3.79Å; K146-T335 HydrophobicContact CG-CG2 3.68Å; K146-T335 WeakPolarHBondContact O-CB 3.21Å; K146-T335 WeakPolarHBondContact O-CG2 3.41Å; K146-T335 PolarHBondContact O-OG1 3.47Å
147M75.9Confident90.7Very high13 Ų1338.8 Ų38.86%0.06419%0.193CC..SBendtrans-66.1142.9-177.3-59.5-57.2153.900111.6M143 P144 E145 K151 R164M143-M147 HydrophobicContact CB-CG 4.19Å; M143-M147 HydrophobicContact CE-CB 4.35Å; M143-M147 HydrophobicContact SD-CB 3.92Å; M143-M147 HydrophobicContact SD-CG 4.45Å; P144-M147 HydrophobicContact CB-CE 4.31Å; P144-M147 HydrophobicContact CG-CE 4.05Å; P144-M147 WeakPolarHBondContact O-CG 3.24Å; P144-M147 PolarHBondContact O-N 2.65Å; E145-M147 PolarHBondContact O-N 3.38Å; M147-K151 HydrophobicContact CB-CD 4.49Å; M147-R164 PolarHBondContact O-NH2 2.97Å
148S78.2Confident90.7Very high2 Ų240.3 Ų40.31%0.01420%0.203CC..  trans-54.9149-173.676.50000114.1E150 K151 V152 N370 K374S148-E150 VanDerWaalsContact C-N 3.25Å; S148-E150 WeakPolarHBondContact CB-OE2 3.36Å; S148-E150 PolarHBondContact O-N 2.83Å; S148-K151 WeakPolarHBondContact O-CB 3.15Å; S148-K151 PolarHBondContact O-N 3.44Å; S148-K151 WeakPolarHBondContact OG-CD 3.42Å; S148-K151 VanDerWaalsContact OG-CG 3.3Å; S148-K151 WeakPolarHBondContact OG-CG 3.4Å; S148-K151 PolarHBondContact OG-N 3.18Å; S148-V152 PolarHBondContact O-N 3.12Å; S148-N370 WeakPolarHBondContact CB-O 3.37Å; S148-N370 PolarHBondContact OG-O 3.16Å; S148-K374 VanDerWaalsContact CA-NZ 3.34Å
149Q86Confident90.6Very high112 Ų11238.1 Ų38.152%0.52321%0.213SC..Hα-helixtrans-66.3-32.4176.1-68.7-61.9-6.600111.2K151 V152 E153Q149-K151 PolarHBondContact O-N 2.96Å; Q149-V152 WeakPolarHBondContact O-CA 3.31Å; Q149-V152 VanDerWaalsContact O-CB 3.3Å; Q149-V152 WeakPolarHBondContact O-CB 3.45Å; Q149-V152 PolarHBondContact O-N 2.95Å; Q149-E153 WeakPolarHBondContact O-CG 3.38Å; Q149-E153 PolarHBondContact O-N 3.19Å
150E90.1Very high90.6Very high27 Ų2738.2 Ų38.213%0.12621%0.214CC..Hα-helixtrans-59.1-37.2175.6-62.389.4157.400112S148 V154 R369 M372 T373S148-E150 VanDerWaalsContact C-N 3.25Å; S148-E150 WeakPolarHBondContact CB-OE2 3.36Å; S148-E150 PolarHBondContact O-N 2.83Å; E150-V154 VanDerWaalsContact O-CG2 3.28Å; E150-V154 WeakPolarHBondContact O-CG2 3.08Å; E150-V154 PolarHBondContact O-N 3.41Å; E150-V154 VanDerWaalsContact O-N 3.1Å; E150-R369 WeakPolarHBondContact CB-O 3.4Å; E150-R369 WeakPolarHBondContact CG-O 3.25Å; E150-M372 HydrophobicContact CG-CB 4.35Å; E150-M372 PolarHBondContact OE1-N 2.87Å; E150-T373 WeakPolarHBondContact OE1-CB 3.32Å; E150-T373 WeakPolarHBondContact OE1-CG2 3.41Å; E150-T373 PolarHBondContact OE1-N 2.91Å; E150-T373 PolarHBondContact OE1-OG1 3.23Å
151K89.5Confident90.6Very high1 Ų142.1 Ų42.10%0.00423%0.233CC..Hα-helixtrans-65.7-40.1173.6-74.2165.9174.3-179.10111.8S121 I126 M147 S148 Q149 V154 L155 E276 N370S121-K151 PolarHBondContact O-NZ 2.94Å; I126-K151 HydrophobicContact CD1-CB 4.45Å; I126-K151 HydrophobicContact CD1-CG 4.13Å; M147-K151 HydrophobicContact CB-CD 4.49Å; S148-K151 WeakPolarHBondContact O-CB 3.15Å; S148-K151 PolarHBondContact O-N 3.44Å; S148-K151 WeakPolarHBondContact OG-CD 3.42Å; S148-K151 VanDerWaalsContact OG-CG 3.3Å; S148-K151 WeakPolarHBondContact OG-CG 3.4Å; S148-K151 PolarHBondContact OG-N 3.18Å; Q149-K151 PolarHBondContact O-N 2.96Å; K151-V154 PolarHBondContact O-N 3.11Å; K151-L155 WeakPolarHBondContact O-CB 3.47Å; K151-L155 VanDerWaalsContact O-CG 3.23Å; K151-L155 WeakPolarHBondContact O-CG 3.44Å; K151-L155 PolarHBondContact O-N 3.24Å; K151-E276 IonicContact NZ-OE2 3.7Å; K151-E276 PolarHBondContact NZ-OE2 3.31Å; K151-N370 HydrophobicContact CG-CB 4.27Å
152V91.2Very high90.4Very high9 Ų944.3 Ų44.36%0.05524%0.244CC..Hα-helixtrans-61.1-48.2177.3174.50000110.6M143 S148 Q149 V154 L155 K156 I162M143-V152 HydrophobicContact SD-CG2 4.28Å; S148-V152 PolarHBondContact O-N 3.12Å; Q149-V152 WeakPolarHBondContact O-CA 3.31Å; Q149-V152 VanDerWaalsContact O-CB 3.3Å; Q149-V152 WeakPolarHBondContact O-CB 3.45Å; Q149-V152 PolarHBondContact O-N 2.95Å; V152-V154 PolarHBondContact O-N 3.31Å; V152-L155 PolarHBondContact O-N 3.22Å; V152-K156 HydrophobicContact CG1-CD 4.14Å; V152-K156 VanDerWaalsContact CG1-CE 3.45Å; V152-K156 HydrophobicContact CG1-CG 4.45Å; V152-K156 WeakPolarHBondContact O-CG 3.18Å; V152-K156 PolarHBondContact O-N 2.96Å; V152-I162 HydrophobicContact CB-CD1 4.28Å; V152-I162 HydrophobicContact CG1-CD1 3.71Å; V152-I162 WeakPolarHBondContact O-CD1 3.37Å
153E94.4Very high90.4Very high101 Ų10146.4 Ų46.447%0.47226%0.257SS..Hα-helixtrans-65.6-38.7-178.1-63.9-49.6129.300112Q149 K156 A157Q149-E153 WeakPolarHBondContact O-CG 3.38Å; Q149-E153 PolarHBondContact O-N 3.19Å; E153-K156 IonicContact OE1-NZ 2.81Å; E153-K156 PolarHBondContact OE1-NZ 3.28Å; E153-A157 WeakPolarHBondContact O-CB 3.32Å; E153-A157 PolarHBondContact O-N 3.48Å
154V95.6Very high90.4Very high30 Ų3050 Ų5018%0.18227%0.27CS..Hα-helixtrans-63.4-43.6172.81730000111.6I126 E150 K151 V152 A157 L158I126-V154 HydrophobicContact CD1-CB 4.27Å; I126-V154 HydrophobicContact CD1-CG1 3.97Å; I126-V154 HydrophobicContact CG1-CG1 3.99Å; I126-V154 HydrophobicContact CG2-CG1 3.91Å; E150-V154 VanDerWaalsContact O-CG2 3.28Å; E150-V154 WeakPolarHBondContact O-CG2 3.08Å; E150-V154 PolarHBondContact O-N 3.41Å; E150-V154 VanDerWaalsContact O-N 3.1Å; K151-V154 PolarHBondContact O-N 3.11Å; V152-V154 PolarHBondContact O-N 3.31Å; V154-A157 PolarHBondContact O-N 3.4Å; V154-L158 HydrophobicContact CG1-CD1 4Å; V154-L158 WeakPolarHBondContact O-CG 3.02Å; V154-L158 PolarHBondContact O-N 3.35Å
155L96.5Very high90.6Very high0 Ų049.6 Ų49.60%027%0.267CS..Hα-helixtrans-63.6-45.9179.1-77171000112.3I126 A129 I141 M143 K151 V152 A157 L158 G159 A160 I162I126-L155 HydrophobicContact CG1-CD2 4Å; I126-L155 HydrophobicContact CG1-CG 4.07Å; A129-L155 HydrophobicContact CB-CD2 3.86Å; I141-L155 HydrophobicContact CB-CD1 4.24Å; I141-L155 HydrophobicContact CG1-CD1 4.41Å; I141-L155 HydrophobicContact CG1-CD2 3.83Å; I141-L155 HydrophobicContact CG2-CD1 3.92Å; M143-L155 HydrophobicContact CE-CD1 3.39Å; M143-L155 HydrophobicContact SD-CD1 4.3Å; K151-L155 WeakPolarHBondContact O-CB 3.47Å; K151-L155 VanDerWaalsContact O-CG 3.23Å; K151-L155 WeakPolarHBondContact O-CG 3.44Å; K151-L155 PolarHBondContact O-N 3.24Å; V152-L155 PolarHBondContact O-N 3.22Å; L155-A157 VanDerWaalsContact C-N 3.33Å; L155-A157 PolarHBondContact O-N 2.94Å; L155-L158 PolarHBondContact O-N 2.93Å; L155-G159 PolarHBondContact O-N 3.48Å; L155-A160 HydrophobicContact CB-CB 4.34Å; L155-A160 HydrophobicContact CD2-CB 4.21Å; L155-A160 WeakPolarHBondContact O-CB 3.4Å; L155-A160 PolarHBondContact O-N 3.01Å; L155-I162 HydrophobicContact CB-CD1 3.66Å; L155-I162 HydrophobicContact CB-CG1 4.11Å; L155-I162 HydrophobicContact CD1-CD1 4.32Å; L155-I162 HydrophobicContact CD1-CG1 4.45Å
156K95.7Very high90.7Very high113 Ų11346.6 Ų46.649%0.49126%0.257SS..Hα-helixtrans-58.9-44.8174.7-71.5174.3-175.4161.70111.3V152 E153 L158 G159 I162V152-K156 HydrophobicContact CG1-CD 4.14Å; V152-K156 VanDerWaalsContact CG1-CE 3.45Å; V152-K156 HydrophobicContact CG1-CG 4.45Å; V152-K156 WeakPolarHBondContact O-CG 3.18Å; V152-K156 PolarHBondContact O-N 2.96Å; E153-K156 IonicContact OE1-NZ 2.81Å; E153-K156 PolarHBondContact OE1-NZ 3.28Å; K156-L158 VanDerWaalsContact C-N 3.25Å; K156-L158 PolarHBondContact O-N 3.42Å; K156-G159 PolarHBondContact O-N 3.36Å; K156-I162 HydrophobicContact CG-CD1 3.78Å
157A97.4Very high90.8Very high89 Ų8947.1 Ų47.174%0.73626%0.263SS*.Hα-helixtrans-64-29.617900000113.1E153 V154 L155 G159E153-A157 WeakPolarHBondContact O-CB 3.32Å; E153-A157 PolarHBondContact O-N 3.48Å; V154-A157 PolarHBondContact O-N 3.4Å; L155-A157 VanDerWaalsContact C-N 3.33Å; L155-A157 PolarHBondContact O-N 2.94Å; A157-G159 PolarHBondContact O-N 3.43Å
158L97.9Very high91Very high53 Ų5352 Ų5228%0.27730%0.298SS..THydrogen-bonded Turntrans-79.1-2.7172.7-71.1169.4000113.5I126 A129 M130 V154 L155 K156I126-L158 HydrophobicContact CG2-CD1 4.1Å; A129-L158 HydrophobicContact CB-CB 3.9Å; A129-L158 HydrophobicContact CB-CD1 3.91Å; M130-L158 HydrophobicContact CB-CD1 4.38Å; M130-L158 HydrophobicContact CB-CD2 4.4Å; V154-L158 HydrophobicContact CG1-CD1 4Å; V154-L158 WeakPolarHBondContact O-CG 3.02Å; V154-L158 PolarHBondContact O-N 3.35Å; L155-L158 PolarHBondContact O-N 2.93Å; K156-L158 VanDerWaalsContact C-N 3.25Å; K156-L158 PolarHBondContact O-N 3.42Å
159G97.2Very high91.1Very high61 Ų6153 Ų5363%0.62931%0.306SS*.THydrogen-bonded Turntrans81.117.1-17900000114.3L155 K156 A157L155-G159 PolarHBondContact O-N 3.48Å; K156-G159 PolarHBondContact O-N 3.36Å; A157-G159 PolarHBondContact O-N 3.43Å
160A97.6Very high91Very high8 Ų850 Ų507%0.06630%0.298CS..  trans-80.9139.9174.600000111.6A129 C139 I141 L155A129-A160 HydrophobicContact CB-CB 3.83Å; C139-A160 HydrophobicContact CB-CB 4.28Å; C139-A160 WeakPolarHBondContact O-CA 3.26Å; I141-A160 HydrophobicContact CG1-CB 4.26Å; L155-A160 HydrophobicContact CB-CB 4.34Å; L155-A160 HydrophobicContact CD2-CB 4.21Å; L155-A160 WeakPolarHBondContact O-CB 3.4Å; L155-A160 PolarHBondContact O-N 3.01Å
161E97.7Very high90.6Very high87 Ų8751 Ų5141%0.40730%0.301SS..EExtended strand (participates in β ladder)trans-80.2142.4166.7-68.6168.1-116.100109.5R138 C139 I140 I141R138-E161 IonicContact CZ-OE1 3.4Å; R138-E161 VanDerWaalsContact CZ-OE1 3.22Å; R138-E161 IonicContact CZ-OE2 2.86Å; R138-E161 IonicContact NE-OE1 3.69Å; R138-E161 PolarHBondContact NE-OE1 3.33Å; R138-E161 IonicContact NE-OE2 3.19Å; R138-E161 VanDerWaalsContact NH2-CD 3.26Å; R138-E161 IonicContact NH2-OE1 2.93Å; R138-E161 PolarHBondContact NH2-OE1 3.33Å; R138-E161 IonicContact NH2-OE2 2.69Å; R138-E161 PolarHBondContact NH2-OE2 2.95Å; C139-E161 PolarHBondContact O-N 3.14Å; I140-E161 CarbonylContact C-O 3.45Å; I140-E161 WeakPolarHBondContact CA-O 3.43Å; I140-E161 HydrophobicContact CG1-CB 4.21Å; I140-E161 HydrophobicContact CG2-CB 4.44Å; I141-E161 PolarHBondContact N-O 2.97Å
162I95.3Very high90.5Very high46 Ų4654.9 Ų54.924%0.23632%0.322CS..EExtended strand (participates in β ladder)trans-123.1126.5-172.9-56.3171.9000109.2I141 M143 V152 L155 K156 R164I141-I162 WeakPolarHBondContact O-CA 3.37Å; M143-I162 HydrophobicContact CG-CG2 4.17Å; M143-I162 HydrophobicContact SD-CG2 4.27Å; V152-I162 HydrophobicContact CB-CD1 4.28Å; V152-I162 HydrophobicContact CG1-CD1 3.71Å; V152-I162 WeakPolarHBondContact O-CD1 3.37Å; L155-I162 HydrophobicContact CB-CD1 3.66Å; L155-I162 HydrophobicContact CB-CG1 4.11Å; L155-I162 HydrophobicContact CD1-CD1 4.32Å; L155-I162 HydrophobicContact CD1-CG1 4.45Å; K156-I162 HydrophobicContact CG-CD1 3.78Å; I162-R164 HydrophobicContact CG2-CG 4.46Å
163V94.4Very high90.4Very high44 Ų4455.7 Ų55.727%0.26733%0.328SS..EExtended strand (participates in β ladder)trans-114.6124172.1-178.80000108.3I140 I141 V142 M143 V180 L184I140-V163 HydrophobicContact CG2-CG2 4.12Å; I141-V163 PolarHBondContact O-N 3.38Å; V142-V163 WeakPolarHBondContact CA-O 3.4Å; V142-V163 HydrophobicContact CG1-CB 4.39Å; V142-V163 HydrophobicContact CG1-CG1 4.41Å; V142-V163 HydrophobicContact CG2-CB 4.31Å; M143-V163 PolarHBondContact N-O 3.42Å; V163-V180 HydrophobicContact CG1-CG1 3.88Å; V163-L184 HydrophobicContact CB-CD1 4.4Å; V163-L184 HydrophobicContact CG1-CD1 4.43Å; V163-L184 HydrophobicContact CG2-CD1 3.92Å
164R89.1Confident90.3Very high76 Ų7655.4 Ų55.429%0.28734%0.335SS..EExtended strand (participates in β ladder)trans-95.1142.6179.8-59.9-72-91.7-151.9-2.4110.1M143 E145 M147 I162M143-R164 CarbonylContact O-C 3.58Å; M143-R164 VanDerWaalsContact O-CA 3.28Å; M143-R164 WeakPolarHBondContact O-CA 3.1Å; M143-R164 PolarHBondContact SD-NH1 2.87Å; M143-R164 VanDerWaalsContact SD-NH1 3.38Å; E145-R164 HydrophobicContact CG-CB 4.07Å; E145-R164 PolarHBondContact O-NH2 3.48Å; M147-R164 PolarHBondContact O-NH2 2.97Å; I162-R164 HydrophobicContact CG2-CG 4.46Å
165T88.5Confident90Very high3 Ų359.7 Ų59.72%0.01835%0.353CS..EExtended strand (participates in β ladder)trans-126.4153.7175.663.70000112V142 M143 P144 E145 E175 H177 V180V142-T165 HydrophobicContact CG1-CG2 3.77Å; M143-T165 PolarHBondContact O-N 2.83Å; P144-T165 CarbonylContact C-O 3.53Å; P144-T165 WeakPolarHBondContact CA-O 3.46Å; E145-T165 PolarHBondContact N-O 2.77Å; T165-E175 WeakPolarHBondContact CB-O 2.99Å; T165-H177 HydrophobicContact CG2-CB 4.21Å; T165-V180 HydrophobicContact CG2-CB 4.04Å; T165-V180 HydrophobicContact CG2-CG1 4.25Å; T165-V180 HydrophobicContact CG2-CG2 3.88Å
166P83.5Confident89.7Confident45 Ų4559.7 Ų59.729%0.29235%0.353SS..  trans-55.8142.7175.9-2534.7000112.6E175P166-E175 HydrophobicContact CG-CB 4.45Å
167N75.9Confident89.3Confident70 Ų7055.5 Ų55.537%0.37434%0.335SS..THydrogen-bonded Turntrans-73.9-28.1179.9-67.6-41000114P144 E145 K146 A169P144-N167 VanDerWaalsContact CB-OD1 3.28Å; P144-N167 WeakPolarHBondContact CB-OD1 2.8Å; E145-N167 PolarHBondContact N-OD1 2.78Å; E145-N167 VanDerWaalsContact N-OD1 3.14Å; K146-N167 VanDerWaalsContact CB-OD1 3.22Å; K146-N167 WeakPolarHBondContact CB-OD1 3.1Å; K146-N167 WeakPolarHBondContact CG-OD1 3.26Å; K146-N167 VanDerWaalsContact N-CG 3.32Å; K146-N167 PolarHBondContact N-ND2 3.44Å; K146-N167 VanDerWaalsContact N-ND2 3.18Å; K146-N167 PolarHBondContact N-OD1 2.7Å; N167-A169 VanDerWaalsContact C-N 3.32Å
168S78.7Confident89Confident115 Ų11551.7 Ų51.780%0.80430%0.302SS*.THydrogen-bonded Turntrans-83.7-6.1-176.151.80000113.6S170S168-S170 PolarHBondContact O-N 3.43Å
169A80.5Confident88.8Confident22 Ų2250.1 Ų50.118%0.18230%0.296CS..  trans-72122.7179.700000110.3N167 E175N167-A169 VanDerWaalsContact C-N 3.32Å; A169-E175 HydrophobicContact CB-CB 4.26Å
170S83.7Confident88.7Confident51 Ų5147.7 Ų47.736%0.35727%0.268SS..  trans-58156.4169.359.50000111S168 D172 S173 S176S168-S170 PolarHBondContact O-N 3.43Å; S170-D172 VanDerWaalsContact CB-OD1 3.25Å; S170-D172 WeakPolarHBondContact CB-OD1 3.42Å; S170-D172 PolarHBondContact O-N 3.03Å; S170-D172 VanDerWaalsContact O-N 3.09Å; S170-D172 PolarHBondContact OG-OD1 3.21Å; S170-S173 VanDerWaalsContact O-CB 3.29Å; S170-S173 WeakPolarHBondContact O-CB 3.44Å; S170-S173 PolarHBondContact O-N 2.74Å; S170-S173 PolarHBondContact OG-N 3.46Å; S170-S176 WeakPolarHBondContact O-CB 3.1Å
171Y82.9Confident88.6Confident47 Ų4747.3 Ų47.318%0.18427%0.265CS..THydrogen-bonded Turntrans-58-28.5-176.380.9-91.4000113.7W19 P20 N21 S176 F282W19-Y171 HydrophobicContact CE3-CD2 4.3Å; W19-Y171 HydrophobicContact CE3-CE2 4.06Å; W19-Y171 HydrophobicContact CZ3-CD2 4.35Å; W19-Y171 HydrophobicContact CZ3-CE2 4.36Å; P20-Y171 HydrophobicContact CG-CD2 4.32Å; N21-Y171 PolarHBondContact ND2-OH 2.92Å; Y171-S176 WeakPolarHBondContact O-CB 2.98Å; Y171-S176 PolarHBondContact O-OG 2.81Å; Y171-F282 HydrophobicContact CD1-CB 3.99Å; Y171-F282 AromaticContact CD1-CD1 3.95Å; Y171-F282 HydrophobicContact CD1-CD1 3.95Å; Y171-F282 HydrophobicContact CD1-CG 4.37Å; Y171-F282 HydrophobicContact CD2-CD1 4.25Å; Y171-F282 HydrophobicContact CE1-CB 3.96Å; Y171-F282 HydrophobicContact CG-CB 4.36Å; Y171-F282 AromaticContact CG-CD1 3.69Å; Y171-F282 HydrophobicContact CG-CD1 3.69Å; Y171-F282 HydrophobicContact CG-CE1 4.36Å; Y171-F282 HydrophobicContact CG-CG 4.29Å
172D86.6Confident88.4Confident82 Ų8245.6 Ų45.644%0.43926%0.257SS..THydrogen-bonded Turntrans-92.9-4.7-179.465.2-18.7000114.2W19 S170W19-D172 HydrophobicContact CH2-CB 3.94Å; W19-D172 HydrophobicContact CZ3-CB 4.13Å; S170-D172 VanDerWaalsContact CB-OD1 3.25Å; S170-D172 WeakPolarHBondContact CB-OD1 3.42Å; S170-D172 PolarHBondContact O-N 3.03Å; S170-D172 VanDerWaalsContact O-N 3.09Å; S170-D172 PolarHBondContact OG-OD1 3.21Å
173S89.9Confident88.5Confident26 Ų2649.4 Ų49.418%0.18227%0.268CS..SBendtrans-63.8144.3174.4172.70000111.2S170 E175 S176 S179S170-S173 VanDerWaalsContact O-CB 3.29Å; S170-S173 WeakPolarHBondContact O-CB 3.44Å; S170-S173 PolarHBondContact O-N 2.74Å; S170-S173 PolarHBondContact OG-N 3.46Å; S173-E175 PolarHBondContact O-N 2.71Å; S173-E175 VanDerWaalsContact O-N 3.14Å; S173-E175 PolarHBondContact OG-N 2.62Å; S173-S176 VanDerWaalsContact O-CB 3.24Å; S173-S176 WeakPolarHBondContact O-CB 2.89Å; S173-S176 PolarHBondContact O-N 2.72Å; S173-S176 PolarHBondContact O-OG 3.16Å; S173-S179 WeakPolarHBondContact O-CB 3.24Å; S173-S179 PolarHBondContact O-OG 3.24Å
174P91.4Very high88.5Confident96 Ų9648.8 Ų48.862%0.62326%0.263SS*.THydrogen-bonded Turntrans-57.2-24170.7-24.534.4000114.1S179P174-S179 WeakPolarHBondContact O-CB 3.42Å
175E90.3Very high88.9Confident119 Ų11946.5 Ų46.556%0.55626%0.258SS*.THydrogen-bonded Turntrans-91.9-3.2179.2-61.5-177.6173.700112.9T165 P166 A169 S173T165-E175 WeakPolarHBondContact CB-O 2.99Å; P166-E175 HydrophobicContact CG-CB 4.45Å; A169-E175 HydrophobicContact CB-CB 4.26Å; S173-E175 PolarHBondContact O-N 2.71Å; S173-E175 VanDerWaalsContact O-N 3.14Å; S173-E175 PolarHBondContact OG-N 2.62Å
176S89.6Confident89.2Confident0 Ų051.7 Ų51.70%029%0.286CS..SBendtrans-65146.6177.593.10000110.5S170 Y171 S173 I178 S179 V180S170-S176 WeakPolarHBondContact O-CB 3.1Å; Y171-S176 WeakPolarHBondContact O-CB 2.98Å; Y171-S176 PolarHBondContact O-OG 2.81Å; S173-S176 VanDerWaalsContact O-CB 3.24Å; S173-S176 WeakPolarHBondContact O-CB 2.89Å; S173-S176 PolarHBondContact O-N 2.72Å; S173-S176 PolarHBondContact O-OG 3.16Å; S176-I178 PolarHBondContact O-N 2.42Å; S176-I178 PolarHBondContact OG-N 2.72Å; S176-S179 PolarHBondContact O-N 2.82Å; S176-S179 VanDerWaalsContact O-N 3.09Å; S176-S179 PolarHBondContact OG-N 3.08Å; S176-S179 PolarHBondContact OG-OG 3.44Å; S176-V180 WeakPolarHBondContact O-CB 3.47Å; S176-V180 WeakPolarHBondContact O-CG2 3.29Å; S176-V180 PolarHBondContact O-N 2.82Å
177H88Confident89.9Confident26 Ų2655.5 Ų55.512%0.1230%0.3CS..Hα-helixtrans-49.9-30.117158.9-57.6000113.7V142 T165 A181V142-H177 HydrophobicContact CG1-CB 3.94Å; V142-H177 WeakPolarHBondContact CG1-O 3.02Å; T165-H177 HydrophobicContact CG2-CB 4.21Å; H177-A181 WeakPolarHBondContact O-CB 3.36Å; H177-A181 PolarHBondContact O-N 3.49Å
178I91Very high90.9Very high9 Ų953.6 Ų53.65%0.04629%0.289CS..Hα-helixtrans-71.8-50.6176.6-55.5-175.1000110.9P20 P119 S176 A181 K182 Y197 F282P20-I178 HydrophobicContact CB-CD1 4.49Å; P20-I178 HydrophobicContact CG-CD1 3.84Å; P119-I178 HydrophobicContact CB-CG1 4.24Å; S176-I178 PolarHBondContact O-N 2.42Å; S176-I178 PolarHBondContact OG-N 2.72Å; I178-A181 PolarHBondContact O-N 2.85Å; I178-K182 PolarHBondContact O-N 2.68Å; I178-Y197 HydrophobicContact CD1-CE2 4.45Å; I178-F282 HydrophobicContact CD1-CE1 4.16Å; I178-F282 HydrophobicContact CD1-CZ 4.26Å
179S93.2Very high91.6Very high20 Ų2053.3 Ų53.314%0.1429%0.285CS..Hα-helixtrans-66.7-39.2179.8-62.90000112.2S173 P174 S176 K182 R183S173-S179 WeakPolarHBondContact O-CB 3.24Å; S173-S179 PolarHBondContact O-OG 3.24Å; P174-S179 WeakPolarHBondContact O-CB 3.42Å; S176-S179 PolarHBondContact O-N 2.82Å; S176-S179 VanDerWaalsContact O-N 3.09Å; S176-S179 PolarHBondContact OG-N 3.08Å; S176-S179 PolarHBondContact OG-OG 3.44Å; S179-K182 WeakPolarHBondContact O-CB 3.25Å; S179-K182 PolarHBondContact O-N 2.99Å; S179-R183 PolarHBondContact O-N 2.84Å
180V94.6Very high92.3Very high9 Ų956.9 Ų56.96%0.05530%0.301CS..Hα-helixtrans-65.5-43.4175.31730000110.9V142 V163 T165 S176 K182 R183 L184V142-V180 HydrophobicContact CG1-CB 4.02Å; V142-V180 HydrophobicContact CG1-CG1 3.82Å; V163-V180 HydrophobicContact CG1-CG1 3.88Å; T165-V180 HydrophobicContact CG2-CB 4.04Å; T165-V180 HydrophobicContact CG2-CG1 4.25Å; T165-V180 HydrophobicContact CG2-CG2 3.88Å; S176-V180 WeakPolarHBondContact O-CB 3.47Å; S176-V180 WeakPolarHBondContact O-CG2 3.29Å; S176-V180 PolarHBondContact O-N 2.82Å; V180-K182 VanDerWaalsContact C-N 3.32Å; V180-K182 PolarHBondContact O-N 3.14Å; V180-R183 PolarHBondContact O-N 2.89Å; V180-L184 HydrophobicContact CG1-CD1 4.05Å; V180-L184 HydrophobicContact CG1-CG 4.48Å; V180-L184 VanDerWaalsContact O-CG 3.32Å; V180-L184 WeakPolarHBondContact O-CG 3.47Å; V180-L184 PolarHBondContact O-N 2.72Å
181A95.3Very high93Very high0 Ų055.3 Ų55.30%029%0.291CS..Hα-helixtrans-59.2-44.4173.600000111.5I117 P119 V142 H177 I178 L184 C185 I193I117-A181 HydrophobicContact CG2-CB 4.02Å; P119-A181 HydrophobicContact CB-CB 4.02Å; P119-A181 HydrophobicContact CG-CB 4.12Å; V142-A181 HydrophobicContact CB-CB 4.19Å; V142-A181 HydrophobicContact CG2-CB 3.85Å; H177-A181 WeakPolarHBondContact O-CB 3.36Å; H177-A181 PolarHBondContact O-N 3.49Å; I178-A181 PolarHBondContact O-N 2.85Å; A181-L184 PolarHBondContact O-N 3.19Å; A181-C185 WeakPolarHBondContact O-CB 3.31Å; A181-C185 PolarHBondContact O-N 3.06Å; A181-I193 HydrophobicContact CB-CD1 4.18Å; A181-I193 WeakPolarHBondContact O-CD1 3.22Å
182K94.7Very high93.6Very high52 Ų5253.8 Ų53.823%0.22629%0.286CS..Hα-helixtrans-57.5-51.6175.2-171.2-161.4-176.1-300111.6W17 I178 S179 V180 L184 C185 D186 I193W17-K182 HydrophobicContact CD2-CD 3.59Å; W17-K182 VanDerWaalsContact CD2-CE 3.44Å; W17-K182 HydrophobicContact CD2-CG 4.13Å; W17-K182 HydrophobicContact CE3-CD 4.06Å; W17-K182 HydrophobicContact CG-CD 3.9Å; W17-K182 HydrophobicContact CG-CG 3.94Å; W17-K182 HydrophobicContact CH2-CD 4.33Å; W17-K182 HydrophobicContact CZ2-CD 3.93Å; W17-K182 HydrophobicContact CZ3-CD 4.41Å; I178-K182 PolarHBondContact O-N 2.68Å; S179-K182 WeakPolarHBondContact O-CB 3.25Å; S179-K182 PolarHBondContact O-N 2.99Å; V180-K182 VanDerWaalsContact C-N 3.32Å; V180-K182 PolarHBondContact O-N 3.14Å; K182-L184 VanDerWaalsContact C-N 3.34Å; K182-L184 PolarHBondContact O-N 3.34Å; K182-C185 WeakPolarHBondContact O-CB 3.34Å; K182-C185 PolarHBondContact O-N 3.39Å; K182-C185 VanDerWaalsContact O-N 3.09Å; K182-D186 VanDerWaalsContact NZ-CG 3.35Å; K182-D186 IonicContact NZ-OD1 2.72Å; K182-D186 PolarHBondContact NZ-OD1 3.44Å; K182-D186 VanDerWaalsContact NZ-OD1 3.12Å; K182-D186 IonicContact NZ-OD2 3.12Å; K182-D186 PolarHBondContact NZ-OD2 3.18Å; K182-D186 PolarHBondContact O-N 2.79Å; K182-I193 HydrophobicContact CB-CD1 4.5Å
183R95.8Very high94Very high126 Ų12650.7 Ų50.748%0.47527%0.269SS..Hα-helixtrans-57-47.3179.8-180176.265.1-151.2-1.8111.5S179 V180 C185 D186 E187S179-R183 PolarHBondContact O-N 2.84Å; V180-R183 PolarHBondContact O-N 2.89Å; R183-C185 VanDerWaalsContact C-N 3.28Å; R183-C185 PolarHBondContact O-N 2.86Å; R183-D186 PolarHBondContact O-N 3.4Å; R183-D186 VanDerWaalsContact O-N 3.14Å; R183-E187 WeakPolarHBondContact CD-OE1 3.34Å; R183-E187 HydrophobicContact CG-CG 4.45Å; R183-E187 WeakPolarHBondContact CG-OE1 3.31Å; R183-E187 WeakPolarHBondContact O-CG 3.49Å; R183-E187 PolarHBondContact O-N 3.11Å
184L96.3Very high94.3Very high30 Ų3049.5 Ų49.516%0.15726%0.26CS..Hα-helixtrans-60.9-37.1176.7-68.8169.1000112.3I117 I140 V142 V163 V180 A181 K182 E187 I188I117-L184 HydrophobicContact CD1-CB 3.95Å; I140-L184 HydrophobicContact CG2-CD1 4.38Å; V142-L184 HydrophobicContact CG2-CD1 3.83Å; V163-L184 HydrophobicContact CB-CD1 4.4Å; V163-L184 HydrophobicContact CG1-CD1 4.43Å; V163-L184 HydrophobicContact CG2-CD1 3.92Å; V180-L184 HydrophobicContact CG1-CD1 4.05Å; V180-L184 HydrophobicContact CG1-CG 4.48Å; V180-L184 VanDerWaalsContact O-CG 3.32Å; V180-L184 WeakPolarHBondContact O-CG 3.47Å; V180-L184 PolarHBondContact O-N 2.72Å; A181-L184 PolarHBondContact O-N 3.19Å; K182-L184 VanDerWaalsContact C-N 3.34Å; K182-L184 PolarHBondContact O-N 3.34Å; L184-E187 PolarHBondContact O-N 3.4Å; L184-I188 HydrophobicContact CB-CD1 4.43Å; L184-I188 WeakPolarHBondContact O-CB 3.33Å; L184-I188 VanDerWaalsContact O-CG1 3.25Å; L184-I188 WeakPolarHBondContact O-CG1 3.26Å; L184-I188 PolarHBondContact O-N 2.96Å
185C96Very high94.4Very high28 Ų2845.7 Ų45.719%0.18924%0.235CC..Hα-helixtrans-68-34.4176.1-168.80000112.9I117 A181 K182 R183 E187 I193I117-C185 HydrophobicContact CD1-CB 4.08Å; A181-C185 WeakPolarHBondContact O-CB 3.31Å; A181-C185 PolarHBondContact O-N 3.06Å; K182-C185 WeakPolarHBondContact O-CB 3.34Å; K182-C185 PolarHBondContact O-N 3.39Å; K182-C185 VanDerWaalsContact O-N 3.09Å; R183-C185 VanDerWaalsContact C-N 3.28Å; R183-C185 PolarHBondContact O-N 2.86Å; C185-E187 VanDerWaalsContact C-N 3.35Å; C185-I193 HydrophobicContact CB-CD1 3.72Å; C185-I193 HydrophobicContact CB-CG1 3.81Å
186D95.7Very high94.6Very high113 Ų11340 Ų4060%0.60421%0.209SC*.Hα-helixtrans-73.3-29.5175.7-64-25.3000111.4K182 R183K182-D186 VanDerWaalsContact NZ-CG 3.35Å; K182-D186 IonicContact NZ-OD1 2.72Å; K182-D186 PolarHBondContact NZ-OD1 3.44Å; K182-D186 VanDerWaalsContact NZ-OD1 3.12Å; K182-D186 IonicContact NZ-OD2 3.12Å; K182-D186 PolarHBondContact NZ-OD2 3.18Å; K182-D186 PolarHBondContact O-N 2.79Å; R183-D186 PolarHBondContact O-N 3.4Å; R183-D186 VanDerWaalsContact O-N 3.14Å
187E97Very high94.8Very high124 Ų12440.1 Ų40.158%0.57921%0.209SC*.Hα-helixtrans-87.2-29.3-177.7-72.2171.1-175.200114.1R183 L184 C185R183-E187 WeakPolarHBondContact CD-OE1 3.34Å; R183-E187 HydrophobicContact CG-CG 4.45Å; R183-E187 WeakPolarHBondContact CG-OE1 3.31Å; R183-E187 WeakPolarHBondContact O-CG 3.49Å; R183-E187 PolarHBondContact O-N 3.11Å; L184-E187 PolarHBondContact O-N 3.4Å; C185-E187 VanDerWaalsContact C-N 3.35Å
188I96.9Very high95.2Very high30 Ų3039.8 Ų39.815%0.15421%0.207CC..SBendtrans-97118.6-175.2-62.7172000110T115 I117 I140 L184 A191T115-I188 HydrophobicContact CG2-CG2 4.42Å; I117-I188 HydrophobicContact CD1-CD1 4.15Å; I140-I188 HydrophobicContact CD1-CD1 3.34Å; L184-I188 HydrophobicContact CB-CD1 4.43Å; L184-I188 WeakPolarHBondContact O-CB 3.33Å; L184-I188 VanDerWaalsContact O-CG1 3.25Å; L184-I188 WeakPolarHBondContact O-CG1 3.26Å; L184-I188 PolarHBondContact O-N 2.96Å; I188-A191 HydrophobicContact CB-CB 3.9Å; I188-A191 HydrophobicContact CG2-CB 3.93Å; I188-A191 VanDerWaalsContact O-CB 3.22Å; I188-A191 WeakPolarHBondContact O-CB 3.37Å; I188-A191 PolarHBondContact O-N 3.35Å
189P95.4Very high95.3Very high109 Ų10939.4 Ų39.471%0.70820%0.204SC*.THydrogen-bonded Turntrans-58.3144.1174.6-23.733.9000112.3A191P189-A191 PolarHBondContact O-N 2.81Å; P189-A191 VanDerWaalsContact O-N 3.14Å
190D95.1Very high95.3Very high97 Ų9740.4 Ų40.452%0.51921%0.208SC..THydrogen-bonded Turntrans54.729.1179.7-69-57.6000113.9R111 M114 T115R111-D190 IonicContact NH2-OD1 2.81Å; R111-D190 PolarHBondContact NH2-OD1 2.89Å; M114-D190 WeakPolarHBondContact CA-O 3.3Å; M114-D190 WeakPolarHBondContact CB-O 3.25Å; M114-D190 HydrophobicContact CG-CB 4.23Å; T115-D190 PolarHBondContact N-O 3.47Å
191A96.5Very high95.3Very high18 Ų1840 Ų4015%0.14921%0.206CC..EExtended strand (participates in β ladder)trans-91.8153.317100000112.4T115 I117 I188 P189T115-A191 HydrophobicContact CG2-CB 4.48Å; T115-A191 CarbonylContact O-C 3.55Å; T115-A191 VanDerWaalsContact O-CA 3.28Å; T115-A191 WeakPolarHBondContact O-CA 3.34Å; I117-A191 HydrophobicContact CD1-CB 3.74Å; I117-A191 HydrophobicContact CG1-CB 4.25Å; I188-A191 HydrophobicContact CB-CB 3.9Å; I188-A191 HydrophobicContact CG2-CB 3.93Å; I188-A191 VanDerWaalsContact O-CB 3.22Å; I188-A191 WeakPolarHBondContact O-CB 3.37Å; I188-A191 PolarHBondContact O-N 3.35Å; P189-A191 PolarHBondContact O-N 2.81Å; P189-A191 VanDerWaalsContact O-N 3.14Å
192I96.2Very high95.4Very high15 Ų1540 Ų408%0.07721%0.206CC..EExtended strand (participates in β ladder)trans-147.2145.2174.1-169.4169.6000110.9V14 Y109 L110 M114 T115 L116 I117V14-I192 HydrophobicContact CG2-CD1 4.19Å; Y109-I192 HydrophobicContact CD2-CD1 3.45Å; Y109-I192 VanDerWaalsContact CD2-CD1 3.45Å; Y109-I192 HydrophobicContact CE2-CD1 3.71Å; Y109-I192 HydrophobicContact CG-CD1 4.47Å; L110-I192 HydrophobicContact CD2-CG2 3.53Å; M114-I192 HydrophobicContact CE-CB 4.28Å; M114-I192 HydrophobicContact CE-CG2 4.21Å; T115-I192 PolarHBondContact O-N 3.19Å; L116-I192 HydrophobicContact CD2-CG2 3.9Å; I117-I192 PolarHBondContact N-O 3Å
193I95.8Very high95.5Very high17 Ų1738 Ų389%0.08720%0.198CC..EExtended strand (participates in β ladder)trans-98.8122.5168-58.5168.3000108.5I117 A181 K182 C185 D195I117-I193 HydrophobicContact CB-CG1 4.14Å; I117-I193 HydrophobicContact CG2-CG1 4.38Å; I117-I193 VanDerWaalsContact O-CA 3.28Å; I117-I193 WeakPolarHBondContact O-CA 3.36Å; A181-I193 HydrophobicContact CB-CD1 4.18Å; A181-I193 WeakPolarHBondContact O-CD1 3.22Å; K182-I193 HydrophobicContact CB-CD1 4.5Å; C185-I193 HydrophobicContact CB-CD1 3.72Å; C185-I193 HydrophobicContact CB-CG1 3.81Å; I193-D195 VanDerWaalsContact C-N 3.35Å; I193-D195 HydrophobicContact CG2-CB 4.08Å
194L95.1Very high95.5Very high1 Ų132.6 Ų32.61%0.00518%0.179CC..  trans-78.5-24.5179.1-67.4176.2000112.1V14 M100 V101 Y109 L110 L116 E118 L128 N199V14-L194 VanDerWaalsContact CG1-O 3.24Å; V14-L194 WeakPolarHBondContact CG1-O 2.98Å; M100-L194 HydrophobicContact CB-CB 4.35Å; M100-L194 HydrophobicContact CB-CD1 4.13Å; M100-L194 HydrophobicContact CE-CB 4.34Å; M100-L194 HydrophobicContact SD-CB 4.29Å; V101-L194 HydrophobicContact CG2-CD1 3.67Å; Y109-L194 HydrophobicContact CE2-CD2 4.42Å; L110-L194 HydrophobicContact CD1-CD2 4.13Å; L116-L194 HydrophobicContact CD2-CD1 4.23Å; L116-L194 HydrophobicContact CD2-CG 4.45Å; E118-L194 PolarHBondContact OE2-N 2.69Å; L128-L194 HydrophobicContact CD1-CD1 4.4Å; L128-L194 HydrophobicContact CD2-CD1 3.51Å; L194-N199 WeakPolarHBondContact O-CB 3.31Å; L194-N199 PolarHBondContact O-ND2 2.65Å
195D94.2Very high95.6Very high16 Ų1631.4 Ų31.49%0.08617%0.173CC..  trans59.777.2168.4-165.5-22.2000113.5E118 I193 Y197 R198 N199E118-D195 PolarHBondContact OE2-N 3.33Å; I193-D195 VanDerWaalsContact C-N 3.35Å; I193-D195 HydrophobicContact CG2-CB 4.08Å; D195-Y197 PolarHBondContact O-N 3.18Å; D195-Y197 WeakPolarHBondContact OD1-CB 2.97Å; D195-Y197 WeakPolarHBondContact OD1-CD2 3.42Å; D195-Y197 PolarHBondContact OD1-N 3.13Å; D195-R198 PolarHBondContact O-N 2.91Å; D195-R198 VanDerWaalsContact O-N 3.14Å; D195-R198 PolarHBondContact OD1-N 2.74Å; D195-R198 WeakPolarHBondContact OD2-CD 3.2Å; D195-N199 WeakPolarHBondContact O-CB 3.42Å; D195-N199 PolarHBondContact O-N 3.44Å
196Q94.6Very high95.7Very high1 Ų130 Ų301%0.00516%0.164CC..THydrogen-bonded Turntrans-55.5-17.4175.264.7178.1-38.800114.8I96 M100 E118 P119 T120 T124 N202 T231I96-Q196 HydrophobicContact CD1-CB 4.12Å; M100-Q196 HydrophobicContact CE-CB 4.45Å; M100-Q196 HydrophobicContact SD-CB 4.46Å; E118-Q196 WeakPolarHBondContact OE1-CB 3.18Å; E118-Q196 WeakPolarHBondContact OE1-CG 3.15Å; E118-Q196 PolarHBondContact OE1-N 2.79Å; P119-Q196 PolarHBondContact O-NE2 3.36Å; T120-Q196 PolarHBondContact OG1-NE2 2.7Å; T124-Q196 HydrophobicContact CG2-CB 4.34Å; T124-Q196 PolarHBondContact OG1-OE1 3.14Å; Q196-N202 PolarHBondContact O-ND2 3.28Å; Q196-T231 HydrophobicContact CB-CG2 4.27Å; Q196-T231 HydrophobicContact CG-CG2 3.82Å
197Y94.3Very high95.9Very high1 Ų126.2 Ų26.20%0.00414%0.141CC..THydrogen-bonded Turntrans-82.4-23.9-177.5-53.5-75.8000112.5P20 P119 I178 D195 T231 Y280 F282 P284 T285 V286P20-Y197 HydrophobicContact CB-CD2 4.02Å; P20-Y197 HydrophobicContact CB-CG 3.79Å; P119-Y197 HydrophobicContact CG-CE2 4.15Å; I178-Y197 HydrophobicContact CD1-CE2 4.45Å; D195-Y197 PolarHBondContact O-N 3.18Å; D195-Y197 WeakPolarHBondContact OD1-CB 2.97Å; D195-Y197 WeakPolarHBondContact OD1-CD2 3.42Å; D195-Y197 PolarHBondContact OD1-N 3.13Å; Y197-T231 HydrophobicContact CD1-CG2 3.96Å; Y197-T231 HydrophobicContact CE1-CG2 4.01Å; Y197-Y280 AromaticContact CE1-CE1 3.87Å; Y197-Y280 HydrophobicContact CE1-CE1 3.87Å; Y197-Y280 AromaticContact CE1-CE2 3.93Å; Y197-Y280 HydrophobicContact CE1-CE2 3.93Å; Y197-Y280 AromaticContact CE1-CZ 3.49Å; Y197-Y280 VanDerWaalsContact CE1-CZ 3.49Å; Y197-Y280 WeakPolarHBondContact CE1-OH 3.35Å; Y197-Y280 PolarHBondContact OH-OH 2.78Å; Y197-F282 AromaticContact CD1-CE2 3.87Å; Y197-F282 HydrophobicContact CD1-CE2 3.87Å; Y197-F282 AromaticContact CD1-CZ 3.71Å; Y197-F282 HydrophobicContact CD1-CZ 3.71Å; Y197-F282 HydrophobicContact CE1-CE2 4.32Å; Y197-F282 AromaticContact CE1-CZ 3.7Å; Y197-F282 HydrophobicContact CE1-CZ 3.7Å; Y197-F282 HydrophobicContact CG-CE2 4.33Å; Y197-F282 HydrophobicContact CG-CZ 4.29Å; Y197-P284 HydrophobicContact CD1-CB 4.35Å; Y197-P284 HydrophobicContact CD1-CG 4.49Å; Y197-T285 WeakPolarHBondContact O-CB 3.36Å; Y197-T285 PolarHBondContact O-N 3.27Å; Y197-V286 WeakPolarHBondContact O-CG1 2.93Å; Y197-V286 WeakPolarHBondContact O-CG2 3.11Å; Y197-V286 PolarHBondContact O-N 2.85Å
198R95Very high95.9Very high20 Ų2020.7 Ų20.78%0.07512%0.115CC..THydrogen-bonded Turntrans-119.3-32.9-175.8-59.8175.754.183.213.6114W19 E22 D195 L200W19-R198 PolarHBondContact O-NH1 3.46Å; E22-R198 IonicContact OE2-CZ 3.15Å; E22-R198 IonicContact OE2-NH1 3.47Å; E22-R198 PolarHBondContact OE2-NH1 3.2Å; E22-R198 IonicContact OE2-NH2 2.73Å; E22-R198 PolarHBondContact OE2-NH2 3.07Å; D195-R198 PolarHBondContact O-N 2.91Å; D195-R198 VanDerWaalsContact O-N 3.14Å; D195-R198 PolarHBondContact OD1-N 2.74Å; D195-R198 WeakPolarHBondContact OD2-CD 3.2Å; R198-L200 PolarHBondContact O-N 2.95Å
199N94.1Very high96Very high0 Ų019.8 Ų19.80%011%0.11CC..  trans-66.2123.9-172.6-170.5-36.7000111.3D11 V14 M100 L194 D195 G201 N202 V286D11-N199 PolarHBondContact OD2-OD1 3.01Å; V14-N199 HydrophobicContact CG1-CB 4.28Å; V14-N199 WeakPolarHBondContact CG1-ND2 3.23Å; M100-N199 HydrophobicContact CG-CB 4.33Å; M100-N199 HydrophobicContact SD-CB 3.92Å; L194-N199 WeakPolarHBondContact O-CB 3.31Å; L194-N199 PolarHBondContact O-ND2 2.65Å; D195-N199 WeakPolarHBondContact O-CB 3.42Å; D195-N199 PolarHBondContact O-N 3.44Å; N199-G201 PolarHBondContact O-N 3.38Å; N199-G201 VanDerWaalsContact O-N 3.16Å; N199-G201 WeakPolarHBondContact OD1-CA 3.13Å; N199-G201 PolarHBondContact OD1-N 3Å; N199-N202 VanDerWaalsContact O-CB 3.29Å; N199-N202 WeakPolarHBondContact O-CB 3.37Å; N199-N202 PolarHBondContact O-N 3.05Å; N199-V286 WeakPolarHBondContact O-CG1 3.3Å
200L93.5Very high96.1Very high42 Ų4214.6 Ų14.622%0.228%0.077CC..Hα-helixtrans-63.5-23.2-179.6-68166.7000111.9D11 H38 R198 N202 S203 I204D11-L200 VanDerWaalsContact OD2-CB 3.3Å; D11-L200 WeakPolarHBondContact OD2-CB 3.37Å; D11-L200 PolarHBondContact OD2-N 3.19Å; H38-L200 WeakPolarHBondContact CE1-CD1 3.5Å; H38-L200 WeakPolarHBondContact ND1-CD1 3.22Å; R198-L200 PolarHBondContact O-N 2.95Å; L200-N202 PolarHBondContact O-N 3.43Å; L200-N202 VanDerWaalsContact O-N 3.09Å; L200-S203 PolarHBondContact O-N 3.26Å; L200-I204 VanDerWaalsContact O-CB 3.22Å; L200-I204 WeakPolarHBondContact O-CB 3.25Å; L200-I204 WeakPolarHBondContact O-CG2 3.46Å; L200-I204 PolarHBondContact O-N 3.22Å
201G94.7Very high96.3Very high0 Ų010 Ų100%05%0.052CC..Hα-helixtrans-49.2-31169.700000113.3R99 N199 A205R99-G201 WeakPolarHBondContact CG-O 3.21Å; N199-G201 PolarHBondContact O-N 3.38Å; N199-G201 VanDerWaalsContact O-N 3.16Å; N199-G201 WeakPolarHBondContact OD1-CA 3.13Å; N199-G201 PolarHBondContact OD1-N 3Å; G201-A205 VanDerWaalsContact O-CB 3.3Å; G201-A205 WeakPolarHBondContact O-CB 3.47Å; G201-A205 PolarHBondContact O-N 3.27Å
202N96.5Very high96.4Very high0 Ų010.7 Ų10.70%05%0.053CC..Hα-helixtrans-64.8-65.2175.1-172.8-17.5000112.2I96 Q196 N199 L200 H206 T231 G233I96-N202 HydrophobicContact CB-CB 4.46Å; I96-N202 HydrophobicContact CD1-CB 4.42Å; I96-N202 HydrophobicContact CG2-CB 4.39Å; I96-N202 WeakPolarHBondContact CG2-O 3.45Å; I96-N202 WeakPolarHBondContact CG2-OD1 3.47Å; Q196-N202 PolarHBondContact O-ND2 3.28Å; N199-N202 VanDerWaalsContact O-CB 3.29Å; N199-N202 WeakPolarHBondContact O-CB 3.37Å; N199-N202 PolarHBondContact O-N 3.05Å; L200-N202 PolarHBondContact O-N 3.43Å; L200-N202 VanDerWaalsContact O-N 3.09Å; N202-H206 PolarHBondContact O-CD2 3.39Å; N202-T231 PolarHBondContact ND2-OG1 3.04Å; N202-G233 WeakPolarHBondContact OD1-CA 3.32Å
203S97Very high96.5Very high9 Ų910 Ų106%0.0635%0.049CC..Hα-helixtrans-71.3-34.1-175.355.40000112.5L200 A205 H206 Y207 G233 G237L200-S203 PolarHBondContact O-N 3.26Å; S203-A205 PolarHBondContact O-N 2.86Å; S203-H206 PolarHBondContact O-N 2.53Å; S203-Y207 PolarHBondContact O-N 3.48Å; S203-G233 WeakPolarHBondContact CA-O 3.22Å; S203-G237 VanDerWaalsContact O-CA 3.26Å; S203-G237 WeakPolarHBondContact O-CA 3.25Å
204I96.1Very high96.6Very high14 Ų149.2 Ų9.27%0.0725%0.045CC..Hα-helixtrans-70.7-30.5-178.2-153.7164000112.8H38 F39 R99 L200 H206 Y207 D208H38-I204 HydrophobicContact CB-CD1 3.66Å; F39-I204 WeakPolarHBondContact O-CD1 3.32Å; R99-I204 HydrophobicContact CG-CG2 4.03Å; L200-I204 VanDerWaalsContact O-CB 3.22Å; L200-I204 WeakPolarHBondContact O-CB 3.25Å; L200-I204 WeakPolarHBondContact O-CG2 3.46Å; L200-I204 PolarHBondContact O-N 3.22Å; I204-H206 PolarHBondContact O-N 2.92Å; I204-Y207 PolarHBondContact O-N 3.43Å; I204-D208 VanDerWaalsContact O-CB 3.29Å; I204-D208 WeakPolarHBondContact O-CB 3.25Å; I204-D208 PolarHBondContact O-N 3.31Å
205A98Very high96.8Very high4 Ų49.4 Ų9.43%0.0335%0.046CC..Hα-helixtrans-58.8-39.2173.800000111.2R95 I96 R99 G201 S203 Q209R95-A205 HydrophobicContact CB-CB 4.37Å; I96-A205 HydrophobicContact CG2-CB 4.32Å; R99-A205 HydrophobicContact CB-CB 3.8Å; R99-A205 HydrophobicContact CG-CB 4.02Å; G201-A205 VanDerWaalsContact O-CB 3.3Å; G201-A205 WeakPolarHBondContact O-CB 3.47Å; G201-A205 PolarHBondContact O-N 3.27Å; S203-A205 PolarHBondContact O-N 2.86Å; A205-Q209 WeakPolarHBondContact O-CB 3.13Å; A205-Q209 PolarHBondContact O-N 2.93Å
206H98.7Very high97Very high0 Ų013.2 Ų13.20%07%0.066CC..Iπ-helixtrans-77.7-36.8178.8-64.4-54.2000112.7V92 I96 N202 S203 I204 T210 A211 S234 I238V92-H206 VanDerWaalsContact CG2-CE1 3.44Å; V92-H206 WeakPolarHBondContact CG2-CE1 3.22Å; I96-H206 WeakPolarHBondContact CG2-NE2 3.41Å; N202-H206 PolarHBondContact O-CD2 3.39Å; S203-H206 PolarHBondContact O-N 2.53Å; I204-H206 PolarHBondContact O-N 2.92Å; H206-T210 PolarHBondContact ND1-OG1 2.8Å; H206-T210 PolarHBondContact O-N 3.24Å; H206-A211 WeakPolarHBondContact O-CB 3.45Å; H206-A211 PolarHBondContact O-N 2.84Å; H206-S234 WeakPolarHBondContact CD2-CA 3.31Å; H206-S234 PolarHBondContact CD2-OG 2.92Å; H206-S234 PolarHBondContact CE1-OG 3.22Å; H206-S234 PolarHBondContact NE2-OG 2.97Å; H206-I238 HydrophobicContact CB-CG1 4.06Å
207Y98.3Very high97.2Very high33 Ų3316.6 Ų16.613%0.1298%0.082CC..Iπ-helixtrans-64.8-45.5174.5179.5-88.1000112.6H40 S203 I204 G237 R240 K241 E244H40-Y207 AromaticContact CE1-CD1 3.69Å; H40-Y207 AromaticContact CE1-CE1 3.43Å; H40-Y207 VanDerWaalsContact CE1-CE1 3.43Å; H40-Y207 WeakPolarHBondContact CE1-CE1 2.93Å; H40-Y207 AromaticContact ND1-CD1 3.78Å; H40-Y207 AromaticContact ND1-CE1 3.68Å; S203-Y207 PolarHBondContact O-N 3.48Å; I204-Y207 PolarHBondContact O-N 3.43Å; Y207-G237 WeakPolarHBondContact CA-O 3.15Å; Y207-R240 HydrophobicContact CD2-CB 3.92Å; Y207-R240 HydrophobicContact CE2-CB 4.15Å; Y207-K241 HydrophobicContact CD2-CB 3.72Å; Y207-K241 VanDerWaalsContact CE1-CE 3.43Å; Y207-K241 VanDerWaalsContact CE1-NZ 3.26Å; Y207-K241 HydrophobicContact CE2-CB 3.9Å; Y207-K241 HydrophobicContact CE2-CD 4.33Å; Y207-K241 HydrophobicContact CG-CB 4.37Å; Y207-K241 VanDerWaalsContact O-CE 3.29Å; Y207-K241 WeakPolarHBondContact O-CE 2.77Å; Y207-K241 PolarHBondContact OH-NZ 2.88Å; Y207-K241 VanDerWaalsContact OH-NZ 3.12Å; Y207-E244 WeakPolarHBondContact CE2-OE1 3.37Å; Y207-E244 WeakPolarHBondContact CE2-OE2 3.28Å; Y207-E244 PolarHBondContact OH-OE1 3.1Å; Y207-E244 PolarHBondContact OH-OE2 3.15Å
208D98Very high97.4Very high7 Ų716.7 Ų16.74%0.0378%0.083CC..Iπ-helixtrans-76.5-33.9-175.9-75.5-7.5000113.3H40 E41 R99 I204H40-D208 WeakPolarHBondContact CA-OD2 3.31Å; H40-D208 IonicContact CE1-OD1 2.64Å; H40-D208 IonicContact CG-OD1 3.75Å; H40-D208 IonicContact ND1-OD1 3.19Å; H40-D208 PolarHBondContact ND1-OD1 3Å; H40-D208 IonicContact ND1-OD2 3.11Å; E41-D208 HydrophobicContact CB-CB 4.44Å; E41-D208 PolarHBondContact N-OD2 2.93Å; R99-D208 IonicContact CZ-OD2 3.18Å; R99-D208 IonicContact NH1-OD2 3.78Å; R99-D208 PolarHBondContact NH1-OD2 3.19Å; R99-D208 IonicContact NH2-OD2 2.68Å; R99-D208 PolarHBondContact NH2-OD2 3.18Å; I204-D208 VanDerWaalsContact O-CB 3.29Å; I204-D208 WeakPolarHBondContact O-CB 3.25Å; I204-D208 PolarHBondContact O-N 3.31Å
209Q98.4Very high97.5Very high11 Ų1122.8 Ų22.85%0.05112%0.117CC..Iπ-helixtrans-123-62.6-169.3-59.4-68.4-51.600112Q42 A205 A211 E212 E213Q42-Q209 PolarHBondContact O-NE2 2.83Å; A205-Q209 WeakPolarHBondContact O-CB 3.13Å; A205-Q209 PolarHBondContact O-N 2.93Å; Q209-A211 VanDerWaalsContact C-N 3.27Å; Q209-A211 PolarHBondContact O-N 3.31Å; Q209-E212 PolarHBondContact O-N 3.3Å; Q209-E213 WeakPolarHBondContact O-CB 3.47Å; Q209-E213 VanDerWaalsContact O-CG 3.27Å; Q209-E213 WeakPolarHBondContact O-CG 3.4Å; Q209-E213 PolarHBondContact O-N 2.78Å
210T98.7Very high97.6Very high0 Ų024.4 Ų24.40%013%0.134CC..Iπ-helixtrans-57.6-41.4-173.5-49.30000112.2R95 H206 I214 I238 L363R95-T210 WeakPolarHBondContact CD-OG1 3.31Å; R95-T210 PolarHBondContact NE-OG1 2.88Å; H206-T210 PolarHBondContact ND1-OG1 2.8Å; H206-T210 PolarHBondContact O-N 3.24Å; T210-I214 HydrophobicContact CG2-CD1 4.32Å; T210-I214 VanDerWaalsContact O-CG1 3.3Å; T210-I214 WeakPolarHBondContact O-CG1 3.41Å; T210-I214 PolarHBondContact O-N 3.45Å; T210-I214 VanDerWaalsContact O-N 3.1Å; T210-I238 HydrophobicContact CG2-CD1 3.73Å; T210-I238 HydrophobicContact CG2-CG1 4.12Å; T210-L363 HydrophobicContact CG2-CD1 4.33Å
211A98.6Very high97.7Very high0 Ų025 Ų250%014%0.141CC..Hα-helixtrans-71.5-43.3179.600000113.3H206 Q209 E213 I214 L215 I238 K241H206-A211 WeakPolarHBondContact O-CB 3.45Å; H206-A211 PolarHBondContact O-N 2.84Å; Q209-A211 VanDerWaalsContact C-N 3.27Å; Q209-A211 PolarHBondContact O-N 3.31Å; A211-E213 VanDerWaalsContact C-N 3.33Å; A211-I214 PolarHBondContact O-N 3.3Å; A211-L215 WeakPolarHBondContact O-CG 3.41Å; A211-L215 PolarHBondContact O-N 3.19Å; A211-I238 HydrophobicContact CB-CB 4.36Å; A211-I238 HydrophobicContact CB-CG2 3.98Å; A211-K241 HydrophobicContact CB-CB 3.49Å; A211-K241 VanDerWaalsContact CB-CB 3.49Å; A211-K241 HydrophobicContact CB-CG 3.54Å
212E98.4Very high97.8Very high34 Ų3425.4 Ų25.416%0.15914%0.143CC..Hα-helixtrans-66-37.1176.4-65.1-70.817800110.9Y43 Q209 I214 L215 D216 K241 R245Y43-E212 HydrophobicContact CD1-CB 3.77Å; Y43-E212 HydrophobicContact CD2-CB 3.88Å; Y43-E212 HydrophobicContact CE1-CB 4.37Å; Y43-E212 HydrophobicContact CE2-CB 4.47Å; Y43-E212 HydrophobicContact CG-CB 3.5Å; Y43-E212 VanDerWaalsContact CG-CB 3.5Å; Y43-E212 HydrophobicContact CG-CG 4.34Å; Q209-E212 PolarHBondContact O-N 3.3Å; E212-I214 PolarHBondContact O-N 2.99Å; E212-L215 PolarHBondContact O-N 2.83Å; E212-D216 WeakPolarHBondContact O-CB 3.44Å; E212-D216 PolarHBondContact O-N 3.28Å; E212-K241 VanDerWaalsContact OE1-CD 3.29Å; E212-K241 WeakPolarHBondContact OE1-CD 3.37Å; E212-K241 WeakPolarHBondContact OE1-CE 3.49Å; E212-K241 IonicContact OE1-NZ 2.68Å; E212-K241 PolarHBondContact OE1-NZ 3.26Å; E212-R245 IonicContact OE1-NH1 3.69Å; E212-R245 IonicContact OE2-NH1 3.53Å; E212-R245 PolarHBondContact OE2-NH1 3.07Å
213E98.6Very high97.9Very high1 Ų127.3 Ų27.31%0.00515%0.154CC..Hα-helixtrans-58.4-47.2170.7-73.1173.2-15400111.4Y43 R60 T61 K82 R95 Q209 A211 D216 Q217Y43-E213 HydrophobicContact CD2-CG 4.34Å; Y43-E213 HydrophobicContact CE2-CB 4.31Å; Y43-E213 HydrophobicContact CE2-CG 3.53Å; R60-E213 PolarHBondContact N-OE1 3.37Å; R60-E213 PolarHBondContact N-OE2 3.1Å; T61-E213 PolarHBondContact N-OE2 3Å; K82-E213 WeakPolarHBondContact CE-OE2 3.46Å; K82-E213 IonicContact NZ-OE2 3.91Å; K82-E213 PolarHBondContact NZ-OE2 2.92Å; R95-E213 IonicContact CZ-OE1 2.65Å; R95-E213 IonicContact CZ-OE2 2.84Å; R95-E213 IonicContact NH1-OE1 2.68Å; R95-E213 PolarHBondContact NH1-OE1 3.46Å; R95-E213 IonicContact NH1-OE2 2.84Å; R95-E213 IonicContact NH2-OE1 3.7Å; R95-E213 PolarHBondContact NH2-OE1 3.48Å; R95-E213 IonicContact NH2-OE2 3.94Å; R95-E213 PolarHBondContact NH2-OE2 3.21Å; Q209-E213 WeakPolarHBondContact O-CB 3.47Å; Q209-E213 VanDerWaalsContact O-CG 3.27Å; Q209-E213 WeakPolarHBondContact O-CG 3.4Å; Q209-E213 PolarHBondContact O-N 2.78Å; A211-E213 VanDerWaalsContact C-N 3.33Å; E213-D216 PolarHBondContact O-N 3.02Å; E213-Q217 WeakPolarHBondContact O-CB 3.23Å; E213-Q217 WeakPolarHBondContact O-CG 3.36Å; E213-Q217 PolarHBondContact O-N 3.45Å; E213-Q217 PolarHBondContact O-OE1 2.99Å
214I98.7Very high98Very high0 Ų026.9 Ų26.90%015%0.151CC..Hα-helixtrans-62.5-45.4178.4-71.1165000110.7K82 T210 A211 E212 C218 I222 L225 I238 V361K82-I214 HydrophobicContact CD-CG1 4.14Å; K82-I214 HydrophobicContact CG-CD1 4.34Å; K82-I214 HydrophobicContact CG-CG1 4.2Å; T210-I214 HydrophobicContact CG2-CD1 4.32Å; T210-I214 VanDerWaalsContact O-CG1 3.3Å; T210-I214 WeakPolarHBondContact O-CG1 3.41Å; T210-I214 PolarHBondContact O-N 3.45Å; T210-I214 VanDerWaalsContact O-N 3.1Å; A211-I214 PolarHBondContact O-N 3.3Å; E212-I214 PolarHBondContact O-N 2.99Å; I214-C218 WeakPolarHBondContact O-CB 3.35Å; I214-C218 PolarHBondContact O-N 3.24Å; I214-C218 PolarHBondContact O-SG 2.83Å; I214-I222 HydrophobicContact CG2-CD1 4.21Å; I214-I222 HydrophobicContact CG2-CG2 4.26Å; I214-L225 HydrophobicContact CD1-CD1 4.26Å; I214-I238 HydrophobicContact CD1-CD1 4.3Å; I214-I238 HydrophobicContact CD1-CG2 4.01Å; I214-V361 HydrophobicContact CD1-CG1 4.31Å; I214-V361 HydrophobicContact CG1-CG1 4.42Å; I214-V361 HydrophobicContact CG2-CG1 4.19Å; I214-V361 HydrophobicContact CG2-CG2 4.22Å
215L98.4Very high98.1Very high5 Ų526.3 Ų26.33%0.02615%0.148CC..Hα-helixtrans-62-48179.5-74.9168.3000111.1A211 E212 C218 N219 G220 K241 I242 R245 L246A211-L215 WeakPolarHBondContact O-CG 3.41Å; A211-L215 PolarHBondContact O-N 3.19Å; E212-L215 PolarHBondContact O-N 2.83Å; L215-C218 CarbonylContact O-C 3.48Å; L215-C218 PolarHBondContact O-N 2.86Å; L215-N219 PolarHBondContact O-N 3.05Å; L215-G220 WeakPolarHBondContact O-CA 3.08Å; L215-G220 PolarHBondContact O-N 2.78Å; L215-K241 HydrophobicContact CD1-CD 4.48Å; L215-K241 HydrophobicContact CD1-CG 3.96Å; L215-I242 HydrophobicContact CD1-CD1 4.09Å; L215-I242 HydrophobicContact CD2-CD1 3.57Å; L215-I242 HydrophobicContact CG-CD1 3.64Å; L215-R245 HydrophobicContact CD1-CB 4.15Å; L215-R245 HydrophobicContact CD1-CG 3.84Å; L215-R245 HydrophobicContact CD2-CB 4.41Å; L215-L246 HydrophobicContact CD2-CD1 3.77Å; L215-L246 HydrophobicContact CD2-CG 4.37Å
216D98.1Very high98.2Very high95 Ų9526.1 Ų26.151%0.50815%0.146SC..Hα-helixtrans-61.1-51.2177.8-175.648.4000111.2Y43 E212 E213 C218 N219Y43-D216 HydrophobicContact CE1-CB 3.79Å; Y43-D216 PolarHBondContact OH-OD2 3.03Å; E212-D216 WeakPolarHBondContact O-CB 3.44Å; E212-D216 PolarHBondContact O-N 3.28Å; E213-D216 PolarHBondContact O-N 3.02Å; D216-C218 PolarHBondContact O-N 2.8Å; D216-N219 PolarHBondContact O-N 2.81Å
217Q98.4Very high98.1Very high72 Ų7226.1 Ų26.134%0.33615%0.146SC..Hα-helixtrans-62.4-26.4178.7-69.8170.1-36.700113.4T61 L63 E213T61-Q217 PolarHBondContact O-NE2 3.5Å; L63-Q217 HydrophobicContact CB-CB 4.18Å; L63-Q217 HydrophobicContact CB-CG 4.48Å; L63-Q217 HydrophobicContact CD2-CB 3.7Å; E213-Q217 WeakPolarHBondContact O-CB 3.23Å; E213-Q217 WeakPolarHBondContact O-CG 3.36Å; E213-Q217 PolarHBondContact O-N 3.45Å; E213-Q217 PolarHBondContact O-OE1 2.99Å
218C98.2Very high98Very high4 Ų425.1 Ų25.13%0.02715%0.146CC..THydrogen-bonded Turntrans-95.17.4177.4-66.30000114L63 I214 L215 D216 G220 S221 I222 K359L63-C218 WeakPolarHBondContact CD2-SG 3.07Å; I214-C218 WeakPolarHBondContact O-CB 3.35Å; I214-C218 PolarHBondContact O-N 3.24Å; I214-C218 PolarHBondContact O-SG 2.83Å; L215-C218 CarbonylContact O-C 3.48Å; L215-C218 PolarHBondContact O-N 2.86Å; D216-C218 PolarHBondContact O-N 2.8Å; C218-G220 PolarHBondContact O-N 2.87Å; C218-S221 WeakPolarHBondContact CB-O 3.07Å; C218-S221 PolarHBondContact O-N 2.86Å; C218-I222 HydrophobicContact CB-CG2 3.49Å; C218-I222 VanDerWaalsContact CB-CG2 3.49Å; C218-I222 WeakPolarHBondContact SG-CG2 3.29Å; C218-K359 PolarHBondContact O-NZ 3.26Å
219N97.3Very high98Very high148 Ų14824.8 Ų24.879%0.79114%0.144SC*.THydrogen-bonded Turntrans53.140.9-173.4-60.3-43.1000112.8L215 D216 S221L215-N219 PolarHBondContact O-N 3.05Å; D216-N219 PolarHBondContact O-N 2.81Å; N219-S221 VanDerWaalsContact C-N 3.27Å; N219-S221 PolarHBondContact O-N 3.43Å
220G96.3Very high97.7Very high34 Ų3424.6 Ų24.635%0.35115%0.145SC..THydrogen-bonded Turntrans71.212.1178.800000115.3L215 C218 L246L215-G220 WeakPolarHBondContact O-CA 3.08Å; L215-G220 PolarHBondContact O-N 2.78Å; C218-G220 PolarHBondContact O-N 2.87Å; G220-L246 WeakPolarHBondContact O-CD2 3.2Å
221S95.9Very high97.6Very high54 Ų5424.9 Ų24.938%0.37815%0.147SC..  trans-128.1106.7-175.6169.20000111.6C218 N219 K359C218-S221 WeakPolarHBondContact CB-O 3.07Å; C218-S221 PolarHBondContact O-N 2.86Å; N219-S221 VanDerWaalsContact C-N 3.27Å; N219-S221 PolarHBondContact O-N 3.43Å; S221-K359 WeakPolarHBondContact O-CD 3.32Å; S221-K359 PolarHBondContact O-NZ 2.75Å; S221-K359 VanDerWaalsContact O-NZ 3.11Å
222I97.9Very high97.5Very high8 Ų825 Ų254%0.04115%0.148CC..  trans-135.3148167.966.7167.4000109.7I214 C218 I242 L246 A249 V361I214-I222 HydrophobicContact CG2-CD1 4.21Å; I214-I222 HydrophobicContact CG2-CG2 4.26Å; C218-I222 HydrophobicContact CB-CG2 3.49Å; C218-I222 VanDerWaalsContact CB-CG2 3.49Å; C218-I222 WeakPolarHBondContact SG-CG2 3.29Å; I222-I242 HydrophobicContact CD1-CD1 3.45Å; I222-I242 VanDerWaalsContact CD1-CD1 3.45Å; I222-I242 HydrophobicContact CD1-CG1 3.83Å; I222-I242 HydrophobicContact CD1-CG2 3.9Å; I222-I242 HydrophobicContact CG1-CD1 4.29Å; I222-I242 HydrophobicContact CG1-CG2 4.39Å; I222-L246 HydrophobicContact CG1-CD1 3.61Å; I222-A249 HydrophobicContact CG1-CB 4.46Å; I222-V361 HydrophobicContact CG2-CG2 3.9Å
223D98.6Very high97.5Very high41 Ų4123.4 Ų23.422%0.21914%0.141CC..SBendtrans-110.3-26.9-180-61.4-99.6000112A249 I250 L354 Q358 K359D223-A249 CarbonylContact O-C 3.58Å; D223-A249 WeakPolarHBondContact O-CA 3.48Å; D223-I250 PolarHBondContact O-N 2.83Å; D223-L354 HydrophobicContact CB-CD2 4.24Å; D223-Q358 HydrophobicContact CB-CB 3.99Å; D223-Q358 HydrophobicContact CB-CG 4.44Å; D223-Q358 PolarHBondContact OD1-NE2 2.73Å; D223-Q358 WeakPolarHBondContact OD2-CA 3.13Å; D223-Q358 WeakPolarHBondContact OD2-CB 3.41Å; D223-K359 PolarHBondContact N-O 3.06Å; D223-K359 PolarHBondContact OD2-N 3.24Å
224M98.7Very high97.5Very high0 Ų023.8 Ų23.80%014%0.144CC..EExtended strand (participates in β ladder)trans-145139.6178.2-171.7176.3-67.400112V226 I250 V252 A350 A351 L354 K359 C360 V361M224-V226 HydrophobicContact CG-CG2 4.11Å; M224-V226 HydrophobicContact SD-CG2 4.19Å; M224-I250 CarbonylContact C-O 3.58Å; M224-I250 WeakPolarHBondContact CA-O 3.33Å; M224-I250 HydrophobicContact CE-CB 4.38Å; M224-I250 HydrophobicContact CE-CD1 4.2Å; M224-I250 HydrophobicContact CE-CG2 4.39Å; M224-I250 HydrophobicContact CG-CB 4.39Å; M224-V252 HydrophobicContact CG-CG2 4.04Å; M224-V252 HydrophobicContact SD-CG2 4.01Å; M224-A350 HydrophobicContact SD-CB 3.92Å; M224-A351 HydrophobicContact SD-CB 4.47Å; M224-L354 HydrophobicContact CB-CD1 3.84Å; M224-L354 HydrophobicContact CE-CD1 4.03Å; M224-L354 HydrophobicContact CE-CD2 4.03Å; M224-L354 HydrophobicContact CE-CG 3.96Å; M224-L354 HydrophobicContact SD-CD1 4.27Å; M224-K359 PolarHBondContact N-O 3.19Å; M224-C360 HydrophobicContact CB-CB 4.24Å; M224-C360 CarbonylContact O-C 3.58Å; M224-C360 WeakPolarHBondContact O-CA 3.47Å; M224-V361 PolarHBondContact O-N 2.76Å
225L98.7Very high97.4Very high1 Ų123.8 Ų23.81%0.00514%0.144CC..EExtended strand (participates in β ladder)trans-117.7135.5168.6174.874.5000108.9I214 I238 I250 V251 V252 V361I214-L225 HydrophobicContact CD1-CD1 4.26Å; L225-I238 HydrophobicContact CD1-CG2 4.04Å; L225-I238 HydrophobicContact CD2-CB 3.73Å; L225-I238 HydrophobicContact CD2-CG2 3.27Å; L225-I238 HydrophobicContact CG-CG2 4.29Å; L225-I250 PolarHBondContact N-O 2.83Å; L225-V251 HydrophobicContact CD2-CG1 4.22Å; L225-V251 HydrophobicContact CD2-CG2 4.46Å; L225-V252 PolarHBondContact O-N 2.83Å; L225-V361 CarbonylContact C-O 3.45Å; L225-V361 WeakPolarHBondContact CA-O 3.19Å; L225-V361 HydrophobicContact CD1-CB 4.4Å; L225-V361 HydrophobicContact CD1-CG1 4.33Å
226V98.6Very high97.4Very high0 Ų023.6 Ų23.60%014%0.143CC..EExtended strand (participates in β ladder)trans-125.4122.4175.9-171.70000109.9M224 V252 V254 N343 A346 A347 V361 V362 L363M224-V226 HydrophobicContact CG-CG2 4.11Å; M224-V226 HydrophobicContact SD-CG2 4.19Å; V226-V252 WeakPolarHBondContact CA-O 3.46Å; V226-V252 HydrophobicContact CB-CB 4.47Å; V226-V252 HydrophobicContact CG1-CB 4.32Å; V226-V252 HydrophobicContact CG1-CG1 4.37Å; V226-V252 HydrophobicContact CG2-CB 4.1Å; V226-V252 HydrophobicContact CG2-CG2 4.37Å; V226-V254 HydrophobicContact CG1-CG2 3.62Å; V226-N343 WeakPolarHBondContact CG1-O 3.46Å; V226-A346 HydrophobicContact CG1-CB 4.21Å; V226-A347 HydrophobicContact CB-CB 4.1Å; V226-A347 HydrophobicContact CG1-CB 4.14Å; V226-A347 HydrophobicContact CG2-CB 3.82Å; V226-V361 PolarHBondContact N-O 3.25Å; V226-V362 HydrophobicContact CB-CG1 4.38Å; V226-V362 HydrophobicContact CB-CG2 4.4Å; V226-V362 WeakPolarHBondContact O-CA 3.42Å; V226-L363 PolarHBondContact O-N 2.98Å
227A98.2Very high97.5Very high0 Ų019.1 Ų19.10%012%0.119CC..EExtended strand (participates in β ladder)trans-149.5134.2179.300000112.3V235 V252 G253 V254 L363A227-V235 HydrophobicContact CB-CB 4.14Å; A227-V235 HydrophobicContact CB-CG2 4.32Å; A227-V252 PolarHBondContact N-O 2.7Å; A227-G253 WeakPolarHBondContact O-CA 3.4Å; A227-V254 PolarHBondContact O-N 3.47Å; A227-V254 VanDerWaalsContact O-N 3.08Å; A227-L363 HydrophobicContact CB-CB 4.02Å; A227-L363 HydrophobicContact CB-CD2 4.16Å
228G96.2Very high97.5Very high13 Ų1315.7 Ų15.713%0.13410%0.103CC..EExtended strand (participates in β ladder)trans-74.4144.517600000113.9V254 N343G228-V254 CarbonylContact C-O 3.6Å; G228-V254 VanDerWaalsContact CA-O 3.31Å; G228-V254 WeakPolarHBondContact CA-O 3.4Å; G228-N343 WeakPolarHBondContact CA-OD1 3.38Å; G228-N343 VanDerWaalsContact N-CG 3.33Å; G228-N343 PolarHBondContact N-ND2 3.27Å; G228-N343 PolarHBondContact N-OD1 2.88Å
229A96.5Very high97.5Very high0 Ų015.5 Ų15.50%010%0.102CC..  trans-100.9115.3179.800000110.3V235 V254 L261 I278 G279 W295A229-V235 HydrophobicContact CB-CG1 4.3Å; A229-V254 PolarHBondContact N-O 3.18Å; A229-L261 HydrophobicContact CB-CD1 4.03Å; A229-I278 CarbonylContact O-C 3.6Å; A229-I278 WeakPolarHBondContact O-CA 3.43Å; A229-I278 WeakPolarHBondContact O-CB 3.44Å; A229-G279 PolarHBondContact O-N 2.78Å; A229-W295 HydrophobicContact CB-CH2 3.76Å; A229-W295 HydrophobicContact CB-CZ3 3.7Å
230G93.3Very high97.5Very high7 Ų79.9 Ų9.97%0.0727%0.07CC..SBendtrans-96-95154.200000107.8G232 L261 Y280G230-G232 PolarHBondContact O-N 3.4Å; G230-G232 VanDerWaalsContact O-N 3.14Å; G230-L261 VanDerWaalsContact O-CD1 3.3Å; G230-L261 WeakPolarHBondContact O-CD1 3.37Å; G230-Y280 VanDerWaalsContact O-CD2 3.31Å; G230-Y280 WeakPolarHBondContact O-CD2 3.44Å
231T95.3Very high97.6Very high5 Ų59.3 Ų9.33%0.0316%0.057CC..SBendtrans-63.3-17.4169.969.60000113.3Q196 Y197 N202 G233 P284 V286Q196-T231 HydrophobicContact CB-CG2 4.27Å; Q196-T231 HydrophobicContact CG-CG2 3.82Å; Y197-T231 HydrophobicContact CD1-CG2 3.96Å; Y197-T231 HydrophobicContact CE1-CG2 4.01Å; N202-T231 PolarHBondContact ND2-OG1 3.04Å; T231-G233 VanDerWaalsContact C-N 3.27Å; T231-G233 PolarHBondContact O-N 3.17Å; T231-G233 PolarHBondContact OG1-N 2.74Å; T231-P284 VanDerWaalsContact O-CB 3.25Å; T231-P284 WeakPolarHBondContact O-CB 3.31Å; T231-V286 WeakPolarHBondContact O-CG2 3.28Å
232G96.9Very high97.7Very high3 Ų36.8 Ų6.83%0.0314%0.039CC..SBendtrans83.7-11.9-173.200000115.3G230 S234 V235 T236G230-G232 PolarHBondContact O-N 3.4Å; G230-G232 VanDerWaalsContact O-N 3.14Å; G232-S234 VanDerWaalsContact C-N 3.33Å; G232-S234 PolarHBondContact O-N 3.02Å; G232-V235 VanDerWaalsContact O-CG1 3.29Å; G232-V235 WeakPolarHBondContact O-CG1 3.3Å; G232-V235 PolarHBondContact O-N 3.2Å; G232-T236 VanDerWaalsContact O-CB 3.32Å; G232-T236 WeakPolarHBondContact O-CB 3.4Å; G232-T236 PolarHBondContact O-N 2.74Å; G232-T236 PolarHBondContact O-OG1 2.76Å
233G97.9Very high97.6Very high0 Ų07.6 Ų7.60%04%0.043CC..Hα-helixtrans-59.5-36.9-173.900000114.7N202 S203 T231 G237N202-G233 WeakPolarHBondContact OD1-CA 3.32Å; S203-G233 WeakPolarHBondContact CA-O 3.22Å; T231-G233 VanDerWaalsContact C-N 3.27Å; T231-G233 PolarHBondContact O-N 3.17Å; T231-G233 PolarHBondContact OG1-N 2.74Å; G233-G237 PolarHBondContact O-N 2.92Å
234S98.4Very high97.5Very high9 Ų98.4 Ų8.46%0.0635%0.045CC..Hα-helixtrans-67.9-50.8176.7-49.60000112.7H206 G232 T236 I238H206-S234 WeakPolarHBondContact CD2-CA 3.31Å; H206-S234 PolarHBondContact CD2-OG 2.92Å; H206-S234 PolarHBondContact CE1-OG 3.22Å; H206-S234 PolarHBondContact NE2-OG 2.97Å; G232-S234 VanDerWaalsContact C-N 3.33Å; G232-S234 PolarHBondContact O-N 3.02Å; S234-T236 VanDerWaalsContact C-N 3.32Å; S234-T236 PolarHBondContact O-N 3.34Å; S234-I238 WeakPolarHBondContact O-CB 3.35Å; S234-I238 WeakPolarHBondContact O-CG1 3.46Å; S234-I238 PolarHBondContact O-N 2.82Å
235V98.4Very high97.3Very high1 Ų114.8 Ų14.81%0.0067%0.069CC..Hα-helixtrans-65.8-37.5179.367.40000111.2A227 A229 G232 G239 V251 L287 V292A227-V235 HydrophobicContact CB-CB 4.14Å; A227-V235 HydrophobicContact CB-CG2 4.32Å; A229-V235 HydrophobicContact CB-CG1 4.3Å; G232-V235 VanDerWaalsContact O-CG1 3.29Å; G232-V235 WeakPolarHBondContact O-CG1 3.3Å; G232-V235 PolarHBondContact O-N 3.2Å; V235-G239 WeakPolarHBondContact O-CA 3.37Å; V235-G239 PolarHBondContact O-N 3.01Å; V235-V251 HydrophobicContact CG2-CG1 3.83Å; V235-L287 HydrophobicContact CG1-CD1 3.97Å; V235-V292 HydrophobicContact CG1-CG2 4.36Å; V235-V292 HydrophobicContact CG2-CG2 3.83Å
236T98.5Very high97.2Very high1 Ų116.7 Ų16.71%0.0068%0.079CC..Hα-helixtrans-67-52.6175.6-68.10000112.4G232 S234 I238 G239 R240 V286 D288G232-T236 VanDerWaalsContact O-CB 3.32Å; G232-T236 WeakPolarHBondContact O-CB 3.4Å; G232-T236 PolarHBondContact O-N 2.74Å; G232-T236 PolarHBondContact O-OG1 2.76Å; S234-T236 VanDerWaalsContact C-N 3.32Å; S234-T236 PolarHBondContact O-N 3.34Å; T236-I238 PolarHBondContact O-N 3.03Å; T236-G239 PolarHBondContact O-N 2.56Å; T236-R240 HydrophobicContact CG2-CG 4.31Å; T236-R240 WeakPolarHBondContact O-CB 3.4Å; T236-R240 VanDerWaalsContact O-CG 3.23Å; T236-R240 WeakPolarHBondContact O-CG 3.44Å; T236-R240 PolarHBondContact O-N 3.27Å; T236-V286 WeakPolarHBondContact CG2-O 3.48Å; T236-V286 PolarHBondContact OG1-O 3.26Å; T236-D288 HydrophobicContact CG2-CB 3.55Å; T236-D288 PolarHBondContact OG1-N 3.19Å
237G98.4Very high97.1Very high1 Ų121.1 Ų21.11%0.0111%0.108CC..Hα-helixtrans-61.1-47-177.500000112.3S203 Y207 G233 K241S203-G237 VanDerWaalsContact O-CA 3.26Å; S203-G237 WeakPolarHBondContact O-CA 3.25Å; Y207-G237 WeakPolarHBondContact CA-O 3.15Å; G233-G237 PolarHBondContact O-N 2.92Å; G237-K241 PolarHBondContact O-N 2.94Å
238I98.7Very high97Very high0 Ų030.9 Ų30.90%015%0.151CC..Hα-helixtrans-68.1-48.3177.5-52167.6000110.3H206 T210 A211 I214 L225 S234 T236 R240 K241 I242 L363H206-I238 HydrophobicContact CB-CG1 4.06Å; T210-I238 HydrophobicContact CG2-CD1 3.73Å; T210-I238 HydrophobicContact CG2-CG1 4.12Å; A211-I238 HydrophobicContact CB-CB 4.36Å; A211-I238 HydrophobicContact CB-CG2 3.98Å; I214-I238 HydrophobicContact CD1-CD1 4.3Å; I214-I238 HydrophobicContact CD1-CG2 4.01Å; L225-I238 HydrophobicContact CD1-CG2 4.04Å; L225-I238 HydrophobicContact CD2-CB 3.73Å; L225-I238 HydrophobicContact CD2-CG2 3.27Å; L225-I238 HydrophobicContact CG-CG2 4.29Å; S234-I238 WeakPolarHBondContact O-CB 3.35Å; S234-I238 WeakPolarHBondContact O-CG1 3.46Å; S234-I238 PolarHBondContact O-N 2.82Å; T236-I238 PolarHBondContact O-N 3.03Å; I238-R240 PolarHBondContact O-N 3.18Å; I238-K241 PolarHBondContact O-N 2.88Å; I238-I242 HydrophobicContact CG2-CG1 3.95Å; I238-I242 WeakPolarHBondContact O-CB 3.42Å; I238-I242 VanDerWaalsContact O-CG1 3.31Å; I238-I242 WeakPolarHBondContact O-CG1 3.3Å; I238-I242 PolarHBondContact O-N 2.8Å; I238-L363 HydrophobicContact CD1-CD1 4.25Å; I238-L363 HydrophobicContact CD1-CD2 4.21Å
239G98.4Very high97.1Very high0 Ų030.5 Ų30.50%015%0.146CC..Hα-helixtrans-57.1-45.3-178.600000112.9V235 T236 K241 I242 K243V235-G239 WeakPolarHBondContact O-CA 3.37Å; V235-G239 PolarHBondContact O-N 3.01Å; T236-G239 PolarHBondContact O-N 2.56Å; G239-K241 PolarHBondContact O-N 3.08Å; G239-I242 PolarHBondContact O-N 3.05Å; G239-K243 WeakPolarHBondContact O-CB 3.48Å; G239-K243 VanDerWaalsContact O-CG 3.28Å; G239-K243 WeakPolarHBondContact O-CG 3.3Å; G239-K243 PolarHBondContact O-N 2.91Å
240R97.9Very high97.1Very high30 Ų3033.2 Ų33.211%0.11316%0.16CC..Hα-helixtrans-56.7-51176.4-75.2-172.9168.9-176.7-2.1112.2C26 W28 Y207 T236 I238 K243 E244 D288 A291C26-R240 PolarHBondContact SG-NH1 2.86Å; W28-R240 HydrophobicContact CD2-CB 4.24Å; W28-R240 VanDerWaalsContact CD2-CD 3.42Å; W28-R240 HydrophobicContact CD2-CG 3.65Å; W28-R240 HydrophobicContact CE3-CG 3.72Å; W28-R240 VanDerWaalsContact CE3-NE 3.34Å; W28-R240 HydrophobicContact CG-CG 4.44Å; W28-R240 HydrophobicContact CH2-CB 3.96Å; W28-R240 HydrophobicContact CH2-CG 3.62Å; W28-R240 VanDerWaalsContact CZ2-CA 3.45Å; W28-R240 HydrophobicContact CZ2-CB 3.46Å; W28-R240 VanDerWaalsContact CZ2-CB 3.46Å; W28-R240 HydrophobicContact CZ2-CG 3.54Å; W28-R240 WeakPolarHBondContact CZ2-O 3.5Å; W28-R240 HydrophobicContact CZ3-CG 3.71Å; Y207-R240 HydrophobicContact CD2-CB 3.92Å; Y207-R240 HydrophobicContact CE2-CB 4.15Å; T236-R240 HydrophobicContact CG2-CG 4.31Å; T236-R240 WeakPolarHBondContact O-CB 3.4Å; T236-R240 VanDerWaalsContact O-CG 3.23Å; T236-R240 WeakPolarHBondContact O-CG 3.44Å; T236-R240 PolarHBondContact O-N 3.27Å; I238-R240 PolarHBondContact O-N 3.18Å; R240-K243 PolarHBondContact O-N 3Å; R240-E244 WeakPolarHBondContact O-CG 3.39Å; R240-E244 PolarHBondContact O-N 3.44Å; R240-E244 VanDerWaalsContact O-N 3.12Å; R240-D288 IonicContact CZ-OD2 2.7Å; R240-D288 IonicContact NE-OD2 2.76Å; R240-D288 PolarHBondContact NE-OD2 3.03Å; R240-D288 IonicContact NH2-OD2 3.19Å; R240-D288 PolarHBondContact NH2-OD2 3.01Å; R240-A291 HydrophobicContact CG-CB 3.91Å
241K97.7Very high97.4Very high22 Ų2232.9 Ų32.910%0.09616%0.156CC..Hα-helixtrans-64.1-42.9179.5178.662.467.2178.10112.1Y207 A211 E212 L215 G237 I238 G239 E244 R245Y207-K241 HydrophobicContact CD2-CB 3.72Å; Y207-K241 VanDerWaalsContact CE1-CE 3.43Å; Y207-K241 VanDerWaalsContact CE1-NZ 3.26Å; Y207-K241 HydrophobicContact CE2-CB 3.9Å; Y207-K241 HydrophobicContact CE2-CD 4.33Å; Y207-K241 HydrophobicContact CG-CB 4.37Å; Y207-K241 VanDerWaalsContact O-CE 3.29Å; Y207-K241 WeakPolarHBondContact O-CE 2.77Å; Y207-K241 PolarHBondContact OH-NZ 2.88Å; Y207-K241 VanDerWaalsContact OH-NZ 3.12Å; A211-K241 HydrophobicContact CB-CB 3.49Å; A211-K241 VanDerWaalsContact CB-CB 3.49Å; A211-K241 HydrophobicContact CB-CG 3.54Å; E212-K241 VanDerWaalsContact OE1-CD 3.29Å; E212-K241 WeakPolarHBondContact OE1-CD 3.37Å; E212-K241 WeakPolarHBondContact OE1-CE 3.49Å; E212-K241 IonicContact OE1-NZ 2.68Å; E212-K241 PolarHBondContact OE1-NZ 3.26Å; L215-K241 HydrophobicContact CD1-CD 4.48Å; L215-K241 HydrophobicContact CD1-CG 3.96Å; G237-K241 PolarHBondContact O-N 2.94Å; I238-K241 PolarHBondContact O-N 2.88Å; G239-K241 PolarHBondContact O-N 3.08Å; K241-E244 IonicContact NZ-OE2 2.73Å; K241-E244 PolarHBondContact O-N 3.05Å; K241-R245 HydrophobicContact CD-CG 4.13Å; K241-R245 WeakPolarHBondContact O-CG 3.36Å; K241-R245 PolarHBondContact O-N 3.21Å; K241-R245 VanDerWaalsContact O-N 3.16Å
242I97.7Very high97.5Very high0 Ų032.7 Ų32.70%016%0.155CC..Hα-helixtrans-63.1-42.4178.1-67.5-51.7000110.8L215 I222 I238 G239 E244 R245 L246 A249L215-I242 HydrophobicContact CD1-CD1 4.09Å; L215-I242 HydrophobicContact CD2-CD1 3.57Å; L215-I242 HydrophobicContact CG-CD1 3.64Å; I222-I242 HydrophobicContact CD1-CD1 3.45Å; I222-I242 VanDerWaalsContact CD1-CD1 3.45Å; I222-I242 HydrophobicContact CD1-CG1 3.83Å; I222-I242 HydrophobicContact CD1-CG2 3.9Å; I222-I242 HydrophobicContact CG1-CD1 4.29Å; I222-I242 HydrophobicContact CG1-CG2 4.39Å; I238-I242 HydrophobicContact CG2-CG1 3.95Å; I238-I242 WeakPolarHBondContact O-CB 3.42Å; I238-I242 VanDerWaalsContact O-CG1 3.31Å; I238-I242 WeakPolarHBondContact O-CG1 3.3Å; I238-I242 PolarHBondContact O-N 2.8Å; G239-I242 PolarHBondContact O-N 3.05Å; I242-E244 VanDerWaalsContact C-N 3.34Å; I242-E244 PolarHBondContact O-N 2.95Å; I242-R245 PolarHBondContact O-N 3.34Å; I242-L246 CarbonylContact O-C 3.59Å; I242-L246 WeakPolarHBondContact O-CA 3.28Å; I242-L246 PolarHBondContact O-N 3.19Å; I242-A249 HydrophobicContact CG2-CB 3.63Å
243K96.5Very high97.6Very high26 Ų2632.5 Ų32.511%0.11315%0.154CC..Hα-helixtrans-65.8-33.1178.1-72.9-60.9-167.6-178.70113.8A30 G239 R240 P247 A249 D293A30-K243 HydrophobicContact CB-CB 4.06Å; G239-K243 WeakPolarHBondContact O-CB 3.48Å; G239-K243 VanDerWaalsContact O-CG 3.28Å; G239-K243 WeakPolarHBondContact O-CG 3.3Å; G239-K243 PolarHBondContact O-N 2.91Å; R240-K243 PolarHBondContact O-N 3Å; K243-P247 WeakPolarHBondContact O-CA 3.46Å; K243-A249 PolarHBondContact NZ-O 3.31Å; K243-D293 VanDerWaalsContact CE-OD1 3.32Å; K243-D293 WeakPolarHBondContact CE-OD1 3.48Å; K243-D293 WeakPolarHBondContact CE-OD2 3.35Å; K243-D293 IonicContact NZ-OD1 3.75Å; K243-D293 PolarHBondContact NZ-OD1 3.17Å; K243-D293 IonicContact NZ-OD2 3.55Å; K243-D293 PolarHBondContact NZ-OD2 3.17Å
244E95.9Very high97.6Very high58 Ų5832.5 Ų32.527%0.27115%0.154SC..Hα-helixtrans-66.5-42.2173.1-71.3166-175.200112.2W28 Y207 R240 K241 I242W28-E244 HydrophobicContact CZ2-CG 4.22Å; W28-E244 PolarHBondContact NE1-OE1 2.77Å; Y207-E244 WeakPolarHBondContact CE2-OE1 3.37Å; Y207-E244 WeakPolarHBondContact CE2-OE2 3.28Å; Y207-E244 PolarHBondContact OH-OE1 3.1Å; Y207-E244 PolarHBondContact OH-OE2 3.15Å; R240-E244 WeakPolarHBondContact O-CG 3.39Å; R240-E244 PolarHBondContact O-N 3.44Å; R240-E244 VanDerWaalsContact O-N 3.12Å; K241-E244 IonicContact NZ-OE2 2.73Å; K241-E244 PolarHBondContact O-N 3.05Å; I242-E244 VanDerWaalsContact C-N 3.34Å; I242-E244 PolarHBondContact O-N 2.95Å
245R95.6Very high97.5Very high134 Ų13432.1 Ų32.151%0.50615%0.151SC..Hα-helixtrans-87.9-35-173.4-62.1-67.3-66.2-80.3-1.3113E212 L215 K241 I242E212-R245 IonicContact OE1-NH1 3.69Å; E212-R245 IonicContact OE2-NH1 3.53Å; E212-R245 PolarHBondContact OE2-NH1 3.07Å; L215-R245 HydrophobicContact CD1-CB 4.15Å; L215-R245 HydrophobicContact CD1-CG 3.84Å; L215-R245 HydrophobicContact CD2-CB 4.41Å; K241-R245 HydrophobicContact CD-CG 4.13Å; K241-R245 WeakPolarHBondContact O-CG 3.36Å; K241-R245 PolarHBondContact O-N 3.21Å; K241-R245 VanDerWaalsContact O-N 3.16Å; I242-R245 PolarHBondContact O-N 3.34Å
246L96.8Very high97.2Very high41 Ų4132.1 Ų32.122%0.21515%0.151CC..  trans-137.775.3-173.4-60.2173.7000109.7L215 G220 I222 I242 K248 A249L215-L246 HydrophobicContact CD2-CD1 3.77Å; L215-L246 HydrophobicContact CD2-CG 4.37Å; G220-L246 WeakPolarHBondContact O-CD2 3.2Å; I222-L246 HydrophobicContact CG1-CD1 3.61Å; I242-L246 CarbonylContact O-C 3.59Å; I242-L246 WeakPolarHBondContact O-CA 3.28Å; I242-L246 PolarHBondContact O-N 3.19Å; L246-K248 PolarHBondContact O-N 2.97Å; L246-A249 HydrophobicContact CB-CB 3.95Å; L246-A249 WeakPolarHBondContact O-CB 3.1Å; L246-A249 PolarHBondContact O-N 2.99Å
247P95.6Very high96.8Very high93 Ų9333.5 Ų33.560%0.60416%0.157SC*.THydrogen-bonded Turntrans-57.5-23.4-173.9-26.634.6000115K243K243-P247 WeakPolarHBondContact O-CA 3.46Å
248K96.3Very high96.3Very high205 Ų20534.5 Ų34.589%0.89117%0.168SC*.THydrogen-bonded Turntrans-85.4-14.1179-64.6-176.5179.3179.80114.1L246L246-K248 PolarHBondContact O-N 2.97Å
249A97.7Very high96Very high4 Ų434.6 Ų34.63%0.03317%0.169CC..PPolyproline II helixtrans-68.3140.1178.700000110.2I222 D223 I242 K243 L246I222-A249 HydrophobicContact CG1-CB 4.46Å; D223-A249 CarbonylContact O-C 3.58Å; D223-A249 WeakPolarHBondContact O-CA 3.48Å; I242-A249 HydrophobicContact CG2-CB 3.63Å; K243-A249 PolarHBondContact NZ-O 3.31Å; L246-A249 HydrophobicContact CB-CB 3.95Å; L246-A249 WeakPolarHBondContact O-CB 3.1Å; L246-A249 PolarHBondContact O-N 2.99Å
250I98.2Very high95.7Very high58 Ų5837.5 Ų37.530%0.29718%0.184SC..EExtended strand (participates in β ladder)trans-94.2125.4-176.8-57.9171.5000109.4D223 M224 L225 V252 D293D223-I250 PolarHBondContact O-N 2.83Å; M224-I250 CarbonylContact C-O 3.58Å; M224-I250 WeakPolarHBondContact CA-O 3.33Å; M224-I250 HydrophobicContact CE-CB 4.38Å; M224-I250 HydrophobicContact CE-CD1 4.2Å; M224-I250 HydrophobicContact CE-CG2 4.39Å; M224-I250 HydrophobicContact CG-CB 4.39Å; L225-I250 PolarHBondContact N-O 2.83Å; I250-V252 HydrophobicContact CG2-CG2 4.04Å; I250-D293 WeakPolarHBondContact CA-OD2 3.41Å; I250-D293 HydrophobicContact CG2-CB 4.11Å
251V98.4Very high95.6Very high0 Ų036.1 Ų36.10%018%0.178CC..EExtended strand (participates in β ladder)trans-102.2119.3173.8-179.30000108.9L225 V235 A291 D293 R294L225-V251 HydrophobicContact CD2-CG1 4.22Å; L225-V251 HydrophobicContact CD2-CG2 4.46Å; V235-V251 HydrophobicContact CG2-CG1 3.83Å; V251-A291 VanDerWaalsContact CB-O 3.29Å; V251-A291 WeakPolarHBondContact CB-O 3.28Å; V251-A291 VanDerWaalsContact CG1-O 3.29Å; V251-A291 WeakPolarHBondContact CG1-O 3.23Å; V251-D293 PolarHBondContact N-OD2 2.83Å; V251-D293 PolarHBondContact O-N 3.13Å; V251-R294 PolarHBondContact O-N 3.09Å
252V98.4Very high95.5Very high0 Ų035.2 Ų35.20%018%0.175CC..EExtended strand (participates in β ladder)trans-107.4117.8179.6-175.50000109.7M224 L225 V226 A227 I250 R294 V296 A350M224-V252 HydrophobicContact CG-CG2 4.04Å; M224-V252 HydrophobicContact SD-CG2 4.01Å; L225-V252 PolarHBondContact O-N 2.83Å; V226-V252 WeakPolarHBondContact CA-O 3.46Å; V226-V252 HydrophobicContact CB-CB 4.47Å; V226-V252 HydrophobicContact CG1-CB 4.32Å; V226-V252 HydrophobicContact CG1-CG1 4.37Å; V226-V252 HydrophobicContact CG2-CB 4.1Å; V226-V252 HydrophobicContact CG2-CG2 4.37Å; A227-V252 PolarHBondContact N-O 2.7Å; I250-V252 HydrophobicContact CG2-CG2 4.04Å; V252-R294 WeakPolarHBondContact CA-O 3.39Å; V252-R294 HydrophobicContact CG1-CG 4.39Å; V252-R294 HydrophobicContact CG2-CG 4Å; V252-V296 HydrophobicContact CG1-CB 4.5Å; V252-V296 HydrophobicContact CG1-CG2 3.7Å; V252-A350 HydrophobicContact CG1-CB 4.43Å; V252-A350 HydrophobicContact CG2-CB 4.27Å
253G98.2Very high94.9Very high0 Ų038.4 Ų38.40%020%0.196CC..EExtended strand (participates in β ladder)trans-83.8140.6170.300000110.9A227 R294 W295 V296A227-G253 WeakPolarHBondContact O-CA 3.4Å; G253-R294 PolarHBondContact N-O 3.05Å; G253-W295 CarbonylContact O-C 3.6Å; G253-W295 VanDerWaalsContact O-CA 3.31Å; G253-W295 WeakPolarHBondContact O-CA 3.24Å; G253-V296 PolarHBondContact O-N 2.85Å
254V97.6Very high94.5Very high0 Ų044.3 Ų44.30%023%0.229CC..EExtended strand (participates in β ladder)trans-115.4129.7176.6-171.70000109.9V226 A227 G228 A229 T298 A342 A346V226-V254 HydrophobicContact CG1-CG2 3.62Å; A227-V254 PolarHBondContact O-N 3.47Å; A227-V254 VanDerWaalsContact O-N 3.08Å; G228-V254 CarbonylContact C-O 3.6Å; G228-V254 VanDerWaalsContact CA-O 3.31Å; G228-V254 WeakPolarHBondContact CA-O 3.4Å; A229-V254 PolarHBondContact N-O 3.18Å; V254-T298 HydrophobicContact CG1-CG2 3.47Å; V254-T298 VanDerWaalsContact CG1-CG2 3.47Å; V254-A342 HydrophobicContact CG1-CB 4.36Å; V254-A346 HydrophobicContact CB-CB 4.29Å; V254-A346 HydrophobicContact CG1-CB 3.86Å; V254-A346 HydrophobicContact CG2-CB 3.43Å; V254-A346 VanDerWaalsContact CG2-CB 3.43Å
255D96.2Very high94.2Very high0 Ų044.7 Ų44.70%023%0.232CC..EExtended strand (participates in β ladder)trans-132.6133.1-174.8-174.248000109.5S259 L261 A262 W295 V296 K297 T298D255-S259 WeakPolarHBondContact OD1-CB 3.38Å; D255-S259 PolarHBondContact OD1-OG 3.08Å; D255-L261 WeakPolarHBondContact OD1-CB 3.34Å; D255-A262 HydrophobicContact CB-CB 3.87Å; D255-A262 PolarHBondContact OD2-N 3.5Å; D255-W295 HydrophobicContact CB-CE3 3.99Å; D255-W295 HydrophobicContact CB-CZ3 4.18Å; D255-V296 PolarHBondContact N-O 2.69Å; D255-K297 HydrophobicContact CB-CD 4.16Å; D255-K297 CarbonylContact O-C 3.57Å; D255-K297 VanDerWaalsContact O-CA 3.25Å; D255-K297 WeakPolarHBondContact O-CA 3.35Å; D255-K297 IonicContact OD2-NZ 3.06Å; D255-K297 PolarHBondContact OD2-NZ 2.82Å; D255-T298 PolarHBondContact O-N 3.28Å; D255-T298 PolarHBondContact O-OG1 3.48Å
256P92.2Very high93.7Very high2 Ų243.2 Ų43.21%0.01324%0.24CC..EExtended strand (participates in β ladder)trans-74.6152.1176.831.5-35.9000111.3S259 Y273 I278 K297 T298P256-S259 WeakPolarHBondContact O-CB 3.38Å; P256-S259 PolarHBondContact O-N 3.25Å; P256-Y273 HydrophobicContact CB-CD2 4.18Å; P256-Y273 HydrophobicContact CB-CE2 4.26Å; P256-Y273 HydrophobicContact CB-CG 4.38Å; P256-Y273 HydrophobicContact CG-CD2 4.29Å; P256-Y273 HydrophobicContact CG-CE1 4.3Å; P256-Y273 HydrophobicContact CG-CE2 3.86Å; P256-I278 HydrophobicContact CB-CD1 4.3Å; P256-I278 HydrophobicContact CB-CG1 4.4Å; P256-I278 HydrophobicContact CG-CD1 4.3Å; P256-I278 HydrophobicContact CG-CG1 3.99Å; P256-K297 PolarHBondContact O-NZ 2.91Å; P256-T298 CarbonylContact C-O 3.48Å; P256-T298 WeakPolarHBondContact CA-O 3.49Å
257M91.2Very high92.8Very high29 Ų2944.2 Ų44.214%0.14325%0.245CC..THydrogen-bonded Turntrans-56.8139.2164.4-69.9-59.4-166.100109.9V270 Y273 K297 T298 K299M257-V270 HydrophobicContact CB-CG2 4.49Å; M257-Y273 VanDerWaalsContact O-CD1 3.29Å; M257-Y273 WeakPolarHBondContact O-CD1 3.38Å; M257-K297 HydrophobicContact CE-CB 3.72Å; M257-K297 HydrophobicContact CE-CG 4.38Å; M257-K297 HydrophobicContact SD-CB 3.84Å; M257-K297 HydrophobicContact SD-CD 4.4Å; M257-K297 WeakPolarHBondContact SD-CE 3.27Å; M257-K297 HydrophobicContact SD-CG 4.19Å; M257-T298 PolarHBondContact N-O 2.93Å; M257-K299 HydrophobicContact CB-CG 4.37Å; M257-K299 HydrophobicContact CG-CG 3.62Å
258G87.5Confident91.7Very high23 Ų2343.2 Ų43.224%0.23724%0.235CC..THydrogen-bonded Turntrans92.3-16.3-170.900000114.9N267 V270G258-N267 PolarHBondContact N-OD1 2.86Å; G258-V270 WeakPolarHBondContact CA-O 3.49Å
259S91.8Very high90.3Very high2 Ų241.8 Ų41.81%0.01424%0.237CC..  trans-92151.7172.7170.30000112.7D255 P256 L261 N267 G279 Y280 K297D255-S259 WeakPolarHBondContact OD1-CB 3.38Å; D255-S259 PolarHBondContact OD1-OG 3.08Å; P256-S259 WeakPolarHBondContact O-CB 3.38Å; P256-S259 PolarHBondContact O-N 3.25Å; S259-L261 WeakPolarHBondContact OG-CG 3.41Å; S259-L261 PolarHBondContact OG-N 3.35Å; S259-N267 PolarHBondContact O-ND2 2.82Å; S259-G279 VanDerWaalsContact CB-CA 3.43Å; S259-G279 WeakPolarHBondContact OG-CA 3.4Å; S259-Y280 PolarHBondContact OG-N 2.83Å; S259-Y280 PolarHBondContact OG-O 2.87Å; S259-K297 PolarHBondContact O-NZ 3.07Å
260I93.2Very high88.7Confident61 Ų6143.7 Ų43.731%0.31325%0.249SC..  trans-98.41.4179.967.6168.6000113.7A262 Y280 D281 Y283I260-A262 PolarHBondContact O-N 3.25Å; I260-A262 VanDerWaalsContact O-N 3.13Å; I260-Y280 WeakPolarHBondContact CG1-O 3.43Å; I260-Y280 PolarHBondContact N-O 3.3Å; I260-Y280 VanDerWaalsContact N-O 3.1Å; I260-D281 VanDerWaalsContact CD1-O 3.31Å; I260-D281 WeakPolarHBondContact CD1-O 3.47Å; I260-Y283 HydrophobicContact CD1-CD2 4.34Å; I260-Y283 HydrophobicContact CD1-CE1 4.18Å; I260-Y283 HydrophobicContact CD1-CE2 3.83Å; I260-Y283 HydrophobicContact CG1-CE1 4.12Å; I260-Y283 VanDerWaalsContact O-CE1 3.3Å; I260-Y283 WeakPolarHBondContact O-CE1 3.27Å
261L95.3Very high87.3Confident0 Ų046.5 Ų46.50%027%0.273CS..SBendtrans-68.3-15.3-170.3-58.6179.5000114.2A229 G230 D255 S259 P263 F282 Y283 L287 Y289 W295A229-L261 HydrophobicContact CB-CD1 4.03Å; G230-L261 VanDerWaalsContact O-CD1 3.3Å; G230-L261 WeakPolarHBondContact O-CD1 3.37Å; D255-L261 WeakPolarHBondContact OD1-CB 3.34Å; S259-L261 WeakPolarHBondContact OG-CG 3.41Å; S259-L261 PolarHBondContact OG-N 3.35Å; L261-P263 WeakPolarHBondContact O-CD 3.47Å; L261-F282 WeakPolarHBondContact CD2-O 3.43Å; L261-Y283 HydrophobicContact CD2-CD1 4.23Å; L261-L287 HydrophobicContact CB-CD2 4.36Å; L261-L287 HydrophobicContact CD2-CD2 4.05Å; L261-Y289 WeakPolarHBondContact O-CE1 3.44Å; L261-Y289 PolarHBondContact O-OH 3.24Å; L261-W295 HydrophobicContact CB-CH2 4.46Å
262A95.1Very high86.2Confident4 Ų449.1 Ų49.13%0.03329%0.285CS..SBendtrans-105.879.8170.700000111D255 I260 D264 L265 W295 K297D255-A262 HydrophobicContact CB-CB 3.87Å; D255-A262 PolarHBondContact OD2-N 3.5Å; I260-A262 PolarHBondContact O-N 3.25Å; I260-A262 VanDerWaalsContact O-N 3.13Å; A262-D264 VanDerWaalsContact C-N 3.28Å; A262-D264 PolarHBondContact O-N 3.13Å; A262-L265 HydrophobicContact CB-CB 4.45Å; A262-L265 HydrophobicContact CB-CD1 4.3Å; A262-L265 PolarHBondContact O-N 3.34Å; A262-W295 HydrophobicContact CB-CB 3.6Å; A262-W295 HydrophobicContact CB-CD2 3.82Å; A262-W295 HydrophobicContact CB-CE3 3.91Å; A262-W295 HydrophobicContact CB-CG 3.7Å; A262-K297 HydrophobicContact CB-CD 4.06Å
263P85.7Confident85.4Confident66 Ų6650.6 Ų50.643%0.42929%0.291SS..THydrogen-bonded Turntrans-64.4-26-165.525.3-36.3000114.9L261 L265 Y289L261-P263 WeakPolarHBondContact O-CD 3.47Å; P263-L265 VanDerWaalsContact C-N 3.34Å; P263-Y289 HydrophobicContact CG-CE1 4.14Å
264D87.6Confident84.6Confident151 Ų15150.9 Ų50.981%0.80729%0.292SS*.THydrogen-bonded Turntrans-88.80.4-177.3-57.8-44.3000113.5A262A262-D264 VanDerWaalsContact C-N 3.28Å; A262-D264 PolarHBondContact O-N 3.13Å
265L90.3Very high84.1Confident66 Ų6651 Ų5135%0.34629%0.292SS..SBendtrans-111.2142.5-179.7-64.3-178.6000110.8A262 P263 W295 K297A262-L265 HydrophobicContact CB-CB 4.45Å; A262-L265 HydrophobicContact CB-CD1 4.3Å; A262-L265 PolarHBondContact O-N 3.34Å; P263-L265 VanDerWaalsContact C-N 3.34Å; L265-W295 HydrophobicContact CD1-CB 3.73Å; L265-W295 WeakPolarHBondContact CD1-O 3.03Å; L265-K297 HydrophobicContact CB-CD 4.39Å; L265-K297 HydrophobicContact CB-CG 3.83Å; L265-K297 HydrophobicContact CD1-CG 3.86Å
266P84.5Confident83.5Confident102 Ų10251.3 Ų51.366%0.66229%0.294SS*.  trans-61.6144.5177.427.2-34.3000110.5
267N78.6Confident83.2Confident62 Ų6252.1 Ų52.133%0.33230%0.303SS..  trans-111.1131.2168.9-140.78.5000107.2G258 S259 K297G258-N267 PolarHBondContact N-OD1 2.86Å; S259-N267 PolarHBondContact O-ND2 2.82Å; N267-K297 WeakPolarHBondContact OD1-CE 3.4Å; N267-K297 PolarHBondContact OD1-NZ 3.03Å
268D71.7Confident83.3Confident72 Ų7251 Ų5139%0.38530%0.297SS..  trans-68.8165167.9-65.1-20.7000108.7V270 K299D268-V270 HydrophobicContact CB-CG2 3.87Å; D268-V270 PolarHBondContact O-N 2.98Å; D268-K299 VanDerWaalsContact OD2-CE 3.26Å; D268-K299 WeakPolarHBondContact OD2-CE 3.45Å; D268-K299 IonicContact OD2-NZ 3.37Å; D268-K299 PolarHBondContact OD2-NZ 2.95Å
269D67.4Low83.5Confident176 Ų17650.2 Ų50.294%0.94129%0.289SS*.SBendtrans-70.240.8175.8-69.9-34000112.7S271D269-S271 PolarHBondContact O-N 2.92Å
270V64.5Low83.3Confident44 Ų4451.4 Ų51.427%0.26729%0.293SS..  trans-87.6104.6-179.5176.40000108.3M257 G258 D268 F272M257-V270 HydrophobicContact CB-CG2 4.49Å; G258-V270 WeakPolarHBondContact CA-O 3.49Å; D268-V270 HydrophobicContact CB-CG2 3.87Å; D268-V270 PolarHBondContact O-N 2.98Å; V270-F272 WeakPolarHBondContact CG1-O 3.32Å
271S67.3Low83.1Confident117 Ų11752.4 Ų52.482%0.81830%0.299SS*.  trans-81.9-19.5174.357.50000113.5D269D269-S271 PolarHBondContact O-N 2.92Å
272F76.6Confident82.8Confident55 Ų5552.6 Ų52.624%0.24130%0.3CS..  trans-137137.5-174.4178.5-93.1000111.4K146 V270 E274 T333K146-F272 HydrophobicContact CD-CE2 4.47Å; V270-F272 WeakPolarHBondContact CG1-O 3.32Å; F272-E274 VanDerWaalsContact CE1-CD 3.5Å; F272-E274 HydrophobicContact CE1-CG 4.16Å; F272-E274 WeakPolarHBondContact CE1-OE2 3.38Å; F272-E274 WeakPolarHBondContact CZ-OE2 3.28Å; F272-T333 HydrophobicContact CZ-CG2 4.43Å
273Y80.9Confident82.8Confident31 Ų3157.3 Ų57.312%0.12232%0.317CS..  trans-137.1145.6173.956.5-93000110.1P256 M257 V275 I278 G279 D300P256-Y273 HydrophobicContact CB-CD2 4.18Å; P256-Y273 HydrophobicContact CB-CE2 4.26Å; P256-Y273 HydrophobicContact CB-CG 4.38Å; P256-Y273 HydrophobicContact CG-CD2 4.29Å; P256-Y273 HydrophobicContact CG-CE1 4.3Å; P256-Y273 HydrophobicContact CG-CE2 3.86Å; M257-Y273 VanDerWaalsContact O-CD1 3.29Å; M257-Y273 WeakPolarHBondContact O-CD1 3.38Å; Y273-V275 VanDerWaalsContact CD2-O 3.3Å; Y273-V275 WeakPolarHBondContact CD2-O 3.33Å; Y273-V275 VanDerWaalsContact CE2-O 3.31Å; Y273-V275 WeakPolarHBondContact CE2-O 3.48Å; Y273-I278 WeakPolarHBondContact CE2-O 3.13Å; Y273-I278 PolarHBondContact OH-O 2.83Å; Y273-G279 VanDerWaalsContact OH-C 3.32Å; Y273-G279 WeakPolarHBondContact OH-CA 3.47Å; Y273-G279 PolarHBondContact OH-O 2.95Å; Y273-D300 VanDerWaalsContact CA-OD2 3.31Å; Y273-D300 WeakPolarHBondContact CA-OD2 3.45Å
274E82.2Confident83.3Confident6 Ų654.3 Ų54.33%0.02830%0.298CS..  trans-78.2-35.4-176.8-63.9-67.3-158.400112.3F272 E276 D300 L334 T335 S336 W380 R384 W386F272-E274 VanDerWaalsContact CE1-CD 3.5Å; F272-E274 HydrophobicContact CE1-CG 4.16Å; F272-E274 WeakPolarHBondContact CE1-OE2 3.38Å; F272-E274 WeakPolarHBondContact CZ-OE2 3.28Å; E274-E276 PolarHBondContact O-N 3.37Å; E274-D300 HydrophobicContact CB-CB 4.49Å; E274-D300 PolarHBondContact N-OD1 3.17Å; E274-D300 PolarHBondContact N-OD2 3.07Å; E274-L334 PolarHBondContact OE1-N 3.29Å; E274-L334 PolarHBondContact OE2-N 2.67Å; E274-T335 WeakPolarHBondContact OE2-CA 3.09Å; E274-T335 PolarHBondContact OE2-N 3.45Å; E274-S336 CarbonylContact C-O 3.49Å; E274-S336 CarbonylContact O-C 3.45Å; E274-S336 PolarHBondContact O-N 2.79Å; E274-W380 HydrophobicContact CB-CH2 4.09Å; E274-W380 HydrophobicContact CB-CZ2 4.45Å; E274-W380 HydrophobicContact CG-CH2 4.05Å; E274-W380 HydrophobicContact CG-CZ2 4.28Å; E274-R384 IonicContact OE1-CZ 3.35Å; E274-R384 IonicContact OE1-NE 2.56Å; E274-R384 PolarHBondContact OE1-NE 2.89Å; E274-R384 IonicContact OE1-NH2 3.54Å; E274-R384 PolarHBondContact OE1-NH2 3.33Å; E274-W386 HydrophobicContact CB-CH2 3.92Å; E274-W386 HydrophobicContact CB-CZ3 4.36Å; E274-W386 HydrophobicContact CG-CH2 3.51Å; E274-W386 HydrophobicContact CG-CZ2 4.49Å; E274-W386 HydrophobicContact CG-CZ3 4.1Å
275V86.9Confident83.7Confident2 Ų248.1 Ų48.11%0.01227%0.266CS..EExtended strand (participates in β ladder)trans-59.1118.5-175.9170.20000111.7Y273 I278 D300 L304 S336Y273-V275 VanDerWaalsContact CD2-O 3.3Å; Y273-V275 WeakPolarHBondContact CD2-O 3.33Å; Y273-V275 VanDerWaalsContact CE2-O 3.31Å; Y273-V275 WeakPolarHBondContact CE2-O 3.48Å; V275-I278 HydrophobicContact CG1-CD1 3.84Å; V275-I278 HydrophobicContact CG1-CG1 3.81Å; V275-D300 WeakPolarHBondContact CB-OD1 3.16Å; V275-D300 HydrophobicContact CG2-CB 4.41Å; V275-D300 WeakPolarHBondContact CG2-OD1 3Å; V275-D300 PolarHBondContact N-OD1 2.95Å; V275-L304 HydrophobicContact CG2-CD2 4.16Å; V275-L304 HydrophobicContact CG2-CG 4.21Å; V275-S336 CarbonylContact C-O 3.51Å; V275-S336 WeakPolarHBondContact CA-O 3.33Å
276E84Confident84Confident7 Ų745.4 Ų45.43%0.03325%0.252CS..EExtended strand (participates in β ladder)trans-85.9143.5-179.5-64.6-179.5-119.900113.1K151 E274 T335 S336 Y371 K374K151-E276 IonicContact NZ-OE2 3.7Å; K151-E276 PolarHBondContact NZ-OE2 3.31Å; E274-E276 PolarHBondContact O-N 3.37Å; E276-T335 HydrophobicContact CG-CG2 3.83Å; E276-T335 WeakPolarHBondContact OE1-CB 3.39Å; E276-S336 WeakPolarHBondContact CG-O 3.36Å; E276-S336 PolarHBondContact N-O 2.62Å; E276-Y371 HydrophobicContact CB-CE1 4.3Å; E276-K374 IonicContact OE1-NZ 3.37Å; E276-K374 PolarHBondContact OE1-NZ 3.19Å
277G86Confident84.6Confident19 Ų1941.1 Ų41.120%0.19622%0.223CC..SBendtrans96.1-5.116500000116.7
278I91.8Very high85.5Confident6 Ų639.3 Ų39.33%0.03121%0.214CC..  trans-126.8158.3173.657.1172.3000110.8A229 P256 Y273 V275 A342A229-I278 CarbonylContact O-C 3.6Å; A229-I278 WeakPolarHBondContact O-CA 3.43Å; A229-I278 WeakPolarHBondContact O-CB 3.44Å; P256-I278 HydrophobicContact CB-CD1 4.3Å; P256-I278 HydrophobicContact CB-CG1 4.4Å; P256-I278 HydrophobicContact CG-CD1 4.3Å; P256-I278 HydrophobicContact CG-CG1 3.99Å; Y273-I278 WeakPolarHBondContact CE2-O 3.13Å; Y273-I278 PolarHBondContact OH-O 2.83Å; V275-I278 HydrophobicContact CG1-CD1 3.84Å; V275-I278 HydrophobicContact CG1-CG1 3.81Å; I278-A342 HydrophobicContact CD1-CB 3.8Å
279G91.4Very high86.6Confident5 Ų539.2 Ų39.25%0.05221%0.208CC..  trans79148.4-179.600000115.4A229 S259 Y273A229-G279 PolarHBondContact O-N 2.78Å; S259-G279 VanDerWaalsContact CB-CA 3.43Å; S259-G279 WeakPolarHBondContact OG-CA 3.4Å; Y273-G279 VanDerWaalsContact OH-C 3.32Å; Y273-G279 WeakPolarHBondContact OH-CA 3.47Å; Y273-G279 PolarHBondContact OH-O 2.95Å
280Y89.2Confident87.9Confident28 Ų2839 Ų3911%0.1120%0.199CC..  trans-152.8160.6174-83.2-77.2000111.4Y197 G230 S259 I260 F282 P284Y197-Y280 AromaticContact CE1-CE1 3.87Å; Y197-Y280 HydrophobicContact CE1-CE1 3.87Å; Y197-Y280 AromaticContact CE1-CE2 3.93Å; Y197-Y280 HydrophobicContact CE1-CE2 3.93Å; Y197-Y280 AromaticContact CE1-CZ 3.49Å; Y197-Y280 VanDerWaalsContact CE1-CZ 3.49Å; Y197-Y280 WeakPolarHBondContact CE1-OH 3.35Å; Y197-Y280 PolarHBondContact OH-OH 2.78Å; G230-Y280 VanDerWaalsContact O-CD2 3.31Å; G230-Y280 WeakPolarHBondContact O-CD2 3.44Å; S259-Y280 PolarHBondContact OG-N 2.83Å; S259-Y280 PolarHBondContact OG-O 2.87Å; I260-Y280 WeakPolarHBondContact CG1-O 3.43Å; I260-Y280 PolarHBondContact N-O 3.3Å; I260-Y280 VanDerWaalsContact N-O 3.1Å; Y280-F282 VanDerWaalsContact C-N 3.35Å; Y280-F282 HydrophobicContact CD1-CD1 4.11Å; Y280-F282 AromaticContact CD1-CE1 3.34Å; Y280-F282 HydrophobicContact CD1-CE1 3.34Å; Y280-F282 AromaticContact CD1-CZ 3.64Å; Y280-F282 HydrophobicContact CD1-CZ 3.64Å; Y280-F282 AromaticContact CE1-CE1 3.92Å; Y280-F282 HydrophobicContact CE1-CE1 3.92Å; Y280-F282 AromaticContact CE1-CZ 3.98Å; Y280-F282 HydrophobicContact CE1-CZ 3.98Å; Y280-F282 HydrophobicContact CG-CE1 4.02Å; Y280-F282 HydrophobicContact CG-CZ 4.08Å; Y280-P284 HydrophobicContact CD2-CG 4.5Å
281D87.3Confident89.4Confident81 Ų8136.9 Ų36.943%0.43319%0.186SC..SBendtrans-904.3173.662.1-28.1000113.2I260I260-D281 VanDerWaalsContact CD1-O 3.31Å; I260-D281 WeakPolarHBondContact CD1-O 3.47Å
282F90.9Very high90.8Very high4 Ų432 Ų322%0.01815%0.152CC..SBendtrans-139.8166.8174.165.3-92.3000110.5P20 N21 Y171 I178 Y197 L261 Y280 P284P20-F282 HydrophobicContact CB-CD2 4.23Å; P20-F282 HydrophobicContact CB-CE2 3.62Å; P20-F282 HydrophobicContact CB-CZ 4.05Å; P20-F282 HydrophobicContact CG-CD2 3.97Å; P20-F282 HydrophobicContact CG-CE1 4.43Å; P20-F282 HydrophobicContact CG-CE2 3.69Å; P20-F282 HydrophobicContact CG-CG 4.47Å; P20-F282 HydrophobicContact CG-CZ 3.94Å; N21-F282 HydrophobicContact CB-CB 4.17Å; N21-F282 HydrophobicContact CB-CD2 4.15Å; Y171-F282 HydrophobicContact CD1-CB 3.99Å; Y171-F282 AromaticContact CD1-CD1 3.95Å; Y171-F282 HydrophobicContact CD1-CD1 3.95Å; Y171-F282 HydrophobicContact CD1-CG 4.37Å; Y171-F282 HydrophobicContact CD2-CD1 4.25Å; Y171-F282 HydrophobicContact CE1-CB 3.96Å; Y171-F282 HydrophobicContact CG-CB 4.36Å; Y171-F282 AromaticContact CG-CD1 3.69Å; Y171-F282 HydrophobicContact CG-CD1 3.69Å; Y171-F282 HydrophobicContact CG-CE1 4.36Å; Y171-F282 HydrophobicContact CG-CG 4.29Å; I178-F282 HydrophobicContact CD1-CE1 4.16Å; I178-F282 HydrophobicContact CD1-CZ 4.26Å; Y197-F282 AromaticContact CD1-CE2 3.87Å; Y197-F282 HydrophobicContact CD1-CE2 3.87Å; Y197-F282 AromaticContact CD1-CZ 3.71Å; Y197-F282 HydrophobicContact CD1-CZ 3.71Å; Y197-F282 HydrophobicContact CE1-CE2 4.32Å; Y197-F282 AromaticContact CE1-CZ 3.7Å; Y197-F282 HydrophobicContact CE1-CZ 3.7Å; Y197-F282 HydrophobicContact CG-CE2 4.33Å; Y197-F282 HydrophobicContact CG-CZ 4.29Å; L261-F282 WeakPolarHBondContact CD2-O 3.43Å; Y280-F282 VanDerWaalsContact C-N 3.35Å; Y280-F282 HydrophobicContact CD1-CD1 4.11Å; Y280-F282 AromaticContact CD1-CE1 3.34Å; Y280-F282 HydrophobicContact CD1-CE1 3.34Å; Y280-F282 AromaticContact CD1-CZ 3.64Å; Y280-F282 HydrophobicContact CD1-CZ 3.64Å; Y280-F282 AromaticContact CE1-CE1 3.92Å; Y280-F282 HydrophobicContact CE1-CE1 3.92Å; Y280-F282 AromaticContact CE1-CZ 3.98Å; Y280-F282 HydrophobicContact CE1-CZ 3.98Å; Y280-F282 HydrophobicContact CG-CE1 4.02Å; Y280-F282 HydrophobicContact CG-CZ 4.08Å; F282-P284 HydrophobicContact CD2-CG 4.28Å; F282-P284 HydrophobicContact CE2-CB 4.24Å; F282-P284 HydrophobicContact CE2-CG 3.87Å; F282-P284 VanDerWaalsContact O-CD 3.32Å; F282-P284 WeakPolarHBondContact O-CD 3.45Å
283Y94.5Very high91.8Very high103 Ų10333.4 Ų33.440%0.40416%0.162SC..  trans-96.1104.7178.4-60.1-67.2000111.4N21 I260 L261 Y289N21-Y283 WeakPolarHBondContact CA-O 3.45Å; N21-Y283 WeakPolarHBondContact CB-O 3.34Å; I260-Y283 HydrophobicContact CD1-CD2 4.34Å; I260-Y283 HydrophobicContact CD1-CE1 4.18Å; I260-Y283 HydrophobicContact CD1-CE2 3.83Å; I260-Y283 HydrophobicContact CG1-CE1 4.12Å; I260-Y283 VanDerWaalsContact O-CE1 3.3Å; I260-Y283 WeakPolarHBondContact O-CE1 3.27Å; L261-Y283 HydrophobicContact CD2-CD1 4.23Å; Y283-Y289 HydrophobicContact CD1-CE2 4.23Å; Y283-Y289 AromaticContact CD1-CZ 3.98Å; Y283-Y289 WeakPolarHBondContact CD1-OH 3.29Å; Y283-Y289 WeakPolarHBondContact CE1-OH 3.4Å
284P95.2Very high92.5Very high4 Ų435.7 Ų35.73%0.02617%0.17CC..  trans-63.2140.3-177.9-21.132.9000112.3P20 Y197 T231 Y280 F282 V286 L287P20-P284 CarbonylContact O-C 3.52Å; P20-P284 WeakPolarHBondContact O-CA 3.31Å; Y197-P284 HydrophobicContact CD1-CB 4.35Å; Y197-P284 HydrophobicContact CD1-CG 4.49Å; T231-P284 VanDerWaalsContact O-CB 3.25Å; T231-P284 WeakPolarHBondContact O-CB 3.31Å; Y280-P284 HydrophobicContact CD2-CG 4.5Å; F282-P284 HydrophobicContact CD2-CG 4.28Å; F282-P284 HydrophobicContact CE2-CB 4.24Å; F282-P284 HydrophobicContact CE2-CG 3.87Å; F282-P284 VanDerWaalsContact O-CD 3.32Å; F282-P284 WeakPolarHBondContact O-CD 3.45Å; P284-V286 HydrophobicContact CB-CG2 4.47Å; P284-V286 PolarHBondContact O-N 3.2Å; P284-V286 VanDerWaalsContact O-N 3.15Å; P284-L287 WeakPolarHBondContact O-CB 3.45Å; P284-L287 PolarHBondContact O-N 3.11Å
285T96.2Very high93.2Very high21 Ų2136.9 Ų36.913%0.12917%0.174CC..THydrogen-bonded Turntrans-54.7-34.6178.5-57.30000113.2P20 E22 A24 Y197 L287P20-T285 PolarHBondContact O-N 2.99Å; P20-T285 PolarHBondContact O-OG1 3.07Å; E22-T285 WeakPolarHBondContact O-CB 3.07Å; E22-T285 WeakPolarHBondContact O-CG2 3.45Å; E22-T285 PolarHBondContact O-OG1 3.02Å; A24-T285 HydrophobicContact CB-CG2 4.14Å; A24-T285 WeakPolarHBondContact CB-O 3.14Å; Y197-T285 WeakPolarHBondContact O-CB 3.36Å; Y197-T285 PolarHBondContact O-N 3.27Å; T285-L287 VanDerWaalsContact C-N 3.31Å; T285-L287 PolarHBondContact O-N 3.03Å
286V96.5Very high93.6Very high9 Ų937.9 Ų37.96%0.05518%0.18CC..THydrogen-bonded Turntrans-77.4-10.4-179.1-63.70000114.5Y197 N199 T231 T236 P284 D288Y197-V286 WeakPolarHBondContact O-CG1 2.93Å; Y197-V286 WeakPolarHBondContact O-CG2 3.11Å; Y197-V286 PolarHBondContact O-N 2.85Å; N199-V286 WeakPolarHBondContact O-CG1 3.3Å; T231-V286 WeakPolarHBondContact O-CG2 3.28Å; T236-V286 WeakPolarHBondContact CG2-O 3.48Å; T236-V286 PolarHBondContact OG1-O 3.26Å; P284-V286 HydrophobicContact CB-CG2 4.47Å; P284-V286 PolarHBondContact O-N 3.2Å; P284-V286 VanDerWaalsContact O-N 3.15Å; V286-D288 PolarHBondContact O-N 2.62Å
287L97.5Very high94.2Very high12 Ų1238.6 Ų38.66%0.06318%0.183CC..  trans-81.6108.2176.8178.557000110.4V235 L261 P284 T285 Y289 W295V235-L287 HydrophobicContact CG1-CD1 3.97Å; L261-L287 HydrophobicContact CB-CD2 4.36Å; L261-L287 HydrophobicContact CD2-CD2 4.05Å; P284-L287 WeakPolarHBondContact O-CB 3.45Å; P284-L287 PolarHBondContact O-N 3.11Å; T285-L287 VanDerWaalsContact C-N 3.31Å; T285-L287 PolarHBondContact O-N 3.03Å; L287-Y289 HydrophobicContact CD2-CE1 4.25Å; L287-Y289 HydrophobicContact CD2-CE2 3.83Å; L287-Y289 VanDerWaalsContact CD2-OH 3.3Å; L287-Y289 WeakPolarHBondContact CD2-OH 3.44Å; L287-Y289 HydrophobicContact CG-CD2 4.35Å; L287-Y289 HydrophobicContact CG-CE2 3.91Å; L287-W295 HydrophobicContact CD1-CH2 4.15Å; L287-W295 HydrophobicContact CD1-CZ2 4.33Å; L287-W295 HydrophobicContact CD2-CH2 4.19Å; L287-W295 HydrophobicContact CD2-CZ2 4.48Å
288D96.9Very high94.5Very high23 Ų2337.8 Ų37.812%0.12318%0.175CC..  trans-96.5106.5171.6-174.93.5000111.4T236 R240 V286 K290 A291T236-D288 HydrophobicContact CG2-CB 3.55Å; T236-D288 PolarHBondContact OG1-N 3.19Å; R240-D288 IonicContact CZ-OD2 2.7Å; R240-D288 IonicContact NE-OD2 2.76Å; R240-D288 PolarHBondContact NE-OD2 3.03Å; R240-D288 IonicContact NH2-OD2 3.19Å; R240-D288 PolarHBondContact NH2-OD2 3.01Å; V286-D288 PolarHBondContact O-N 2.62Å; D288-K290 PolarHBondContact O-N 3.46Å; D288-K290 WeakPolarHBondContact OD1-CB 3.34Å; D288-K290 PolarHBondContact OD1-N 3.1Å; D288-A291 HydrophobicContact CB-CB 4.48Å; D288-A291 WeakPolarHBondContact O-CB 3.37Å; D288-A291 PolarHBondContact O-N 3.14Å; D288-A291 VanDerWaalsContact O-N 3.12Å
289Y95.6Very high94.4Very high71 Ų7142 Ų4228%0.27819%0.193SC..G310 helixtrans-60.9-26.8176.6-74.4-85000113.9L261 P263 Y283 L287 A291 V292 W295L261-Y289 WeakPolarHBondContact O-CE1 3.44Å; L261-Y289 PolarHBondContact O-OH 3.24Å; P263-Y289 HydrophobicContact CG-CE1 4.14Å; Y283-Y289 HydrophobicContact CD1-CE2 4.23Å; Y283-Y289 AromaticContact CD1-CZ 3.98Å; Y283-Y289 WeakPolarHBondContact CD1-OH 3.29Å; Y283-Y289 WeakPolarHBondContact CE1-OH 3.4Å; L287-Y289 HydrophobicContact CD2-CE1 4.25Å; L287-Y289 HydrophobicContact CD2-CE2 3.83Å; L287-Y289 VanDerWaalsContact CD2-OH 3.3Å; L287-Y289 WeakPolarHBondContact CD2-OH 3.44Å; L287-Y289 HydrophobicContact CG-CD2 4.35Å; L287-Y289 HydrophobicContact CG-CE2 3.91Å; Y289-A291 PolarHBondContact O-N 3.09Å; Y289-V292 PolarHBondContact O-N 3.02Å; Y289-V292 VanDerWaalsContact O-N 3.16Å; Y289-W295 AromaticContact CD1-CZ2 3.97Å; Y289-W295 HydrophobicContact CD1-CZ2 3.97Å; Y289-W295 AromaticContact CD1-NE1 3.94Å; Y289-W295 AromaticContact CE1-CZ2 3.64Å; Y289-W295 HydrophobicContact CE1-CZ2 3.64Å
290K94.6Very high94.2Very high170 Ų17043 Ų4374%0.73920%0.197SC*.G310 helixtrans-70.2-14.6177.6-60.9178.1-178.5175.40113D288 V292D288-K290 PolarHBondContact O-N 3.46Å; D288-K290 WeakPolarHBondContact OD1-CB 3.34Å; D288-K290 PolarHBondContact OD1-N 3.1Å; K290-V292 VanDerWaalsContact C-N 3.35Å
291A95.7Very high94Very high0 Ų045.2 Ų45.20%021%0.205CC..G310 helixtrans-85.9-7.3175.800000113R240 V251 D288 Y289R240-A291 HydrophobicContact CG-CB 3.91Å; V251-A291 VanDerWaalsContact CB-O 3.29Å; V251-A291 WeakPolarHBondContact CB-O 3.28Å; V251-A291 VanDerWaalsContact CG1-O 3.29Å; V251-A291 WeakPolarHBondContact CG1-O 3.23Å; D288-A291 HydrophobicContact CB-CB 4.48Å; D288-A291 WeakPolarHBondContact O-CB 3.37Å; D288-A291 PolarHBondContact O-N 3.14Å; D288-A291 VanDerWaalsContact O-N 3.12Å; Y289-A291 PolarHBondContact O-N 3.09Å
292V97.1Very high94.1Very high15 Ų1544 Ų449%0.09120%0.196CC..  trans-116125.8-176.3-174.40000109.4V235 Y289 K290 R294 W295V235-V292 HydrophobicContact CG1-CG2 4.36Å; V235-V292 HydrophobicContact CG2-CG2 3.83Å; Y289-V292 PolarHBondContact O-N 3.02Å; Y289-V292 VanDerWaalsContact O-N 3.16Å; K290-V292 VanDerWaalsContact C-N 3.35Å; V292-R294 VanDerWaalsContact CG1-O 3.32Å; V292-R294 WeakPolarHBondContact CG1-O 3.13Å; V292-W295 HydrophobicContact CB-CZ2 4.4Å; V292-W295 HydrophobicContact CG1-CD2 4.28Å; V292-W295 HydrophobicContact CG1-CG 4.48Å; V292-W295 HydrophobicContact CG1-CZ2 4.24Å; V292-W295 HydrophobicContact CG2-CZ2 4.15Å
293D96.9Very high94.1Very high85 Ų8543.8 Ų43.846%0.45520%0.196SC..SBendtrans-84.6-35.4180-62.4-72.6000112.8K243 I250 V251K243-D293 VanDerWaalsContact CE-OD1 3.32Å; K243-D293 WeakPolarHBondContact CE-OD1 3.48Å; K243-D293 WeakPolarHBondContact CE-OD2 3.35Å; K243-D293 IonicContact NZ-OD1 3.75Å; K243-D293 PolarHBondContact NZ-OD1 3.17Å; K243-D293 IonicContact NZ-OD2 3.55Å; K243-D293 PolarHBondContact NZ-OD2 3.17Å; I250-D293 WeakPolarHBondContact CA-OD2 3.41Å; I250-D293 HydrophobicContact CG2-CB 4.11Å; V251-D293 PolarHBondContact N-OD2 2.83Å; V251-D293 PolarHBondContact O-N 3.13Å
294R95.7Very high93.9Very high79 Ų7938.9 Ų38.930%0.29818%0.176SC..EExtended strand (participates in β ladder)trans-153.3157.3177.364.6179.6-179.5-177.6-1.6111.9V251 V252 G253 V292 A350 D353V251-R294 PolarHBondContact O-N 3.09Å; V252-R294 WeakPolarHBondContact CA-O 3.39Å; V252-R294 HydrophobicContact CG1-CG 4.39Å; V252-R294 HydrophobicContact CG2-CG 4Å; G253-R294 PolarHBondContact N-O 3.05Å; V292-R294 VanDerWaalsContact CG1-O 3.32Å; V292-R294 WeakPolarHBondContact CG1-O 3.13Å; R294-A350 PolarHBondContact NH2-O 2.9Å; R294-D353 IonicContact CZ-OD2 2.76Å; R294-D353 IonicContact NH1-OD2 2.69Å; R294-D353 PolarHBondContact NH1-OD2 2.72Å; R294-D353 IonicContact NH2-OD2 2.73Å
295W97.6Very high93.5Very high31 Ų3140.6 Ų40.612%0.11719%0.185CC..EExtended strand (participates in β ladder)trans-109.4154.8177.2-69.989.8000111.5A229 G253 D255 L261 A262 L265 L287 Y289 V292A229-W295 HydrophobicContact CB-CH2 3.76Å; A229-W295 HydrophobicContact CB-CZ3 3.7Å; G253-W295 CarbonylContact O-C 3.6Å; G253-W295 VanDerWaalsContact O-CA 3.31Å; G253-W295 WeakPolarHBondContact O-CA 3.24Å; D255-W295 HydrophobicContact CB-CE3 3.99Å; D255-W295 HydrophobicContact CB-CZ3 4.18Å; L261-W295 HydrophobicContact CB-CH2 4.46Å; A262-W295 HydrophobicContact CB-CB 3.6Å; A262-W295 HydrophobicContact CB-CD2 3.82Å; A262-W295 HydrophobicContact CB-CE3 3.91Å; A262-W295 HydrophobicContact CB-CG 3.7Å; L265-W295 HydrophobicContact CD1-CB 3.73Å; L265-W295 WeakPolarHBondContact CD1-O 3.03Å; L287-W295 HydrophobicContact CD1-CH2 4.15Å; L287-W295 HydrophobicContact CD1-CZ2 4.33Å; L287-W295 HydrophobicContact CD2-CH2 4.19Å; L287-W295 HydrophobicContact CD2-CZ2 4.48Å; Y289-W295 AromaticContact CD1-CZ2 3.97Å; Y289-W295 HydrophobicContact CD1-CZ2 3.97Å; Y289-W295 AromaticContact CD1-NE1 3.94Å; Y289-W295 AromaticContact CE1-CZ2 3.64Å; Y289-W295 HydrophobicContact CE1-CZ2 3.64Å; V292-W295 HydrophobicContact CB-CZ2 4.4Å; V292-W295 HydrophobicContact CG1-CD2 4.28Å; V292-W295 HydrophobicContact CG1-CG 4.48Å; V292-W295 HydrophobicContact CG1-CZ2 4.24Å; V292-W295 HydrophobicContact CG2-CZ2 4.15Å
296V96.2Very high93.2Very high22 Ų2240.3 Ų40.313%0.13318%0.183CC..EExtended strand (participates in β ladder)trans-130.5124.8170.3177.30000108.7V252 G253 D255 T298 W345 A346V252-V296 HydrophobicContact CG1-CB 4.5Å; V252-V296 HydrophobicContact CG1-CG2 3.7Å; G253-V296 PolarHBondContact O-N 2.85Å; D255-V296 PolarHBondContact N-O 2.69Å; V296-T298 HydrophobicContact CG1-CG2 4.48Å; V296-W345 HydrophobicContact CG1-CE3 4.46Å; V296-W345 HydrophobicContact CG1-CZ3 3.93Å; V296-A346 HydrophobicContact CB-CB 3.91Å; V296-A346 HydrophobicContact CG1-CB 3.7Å; V296-A346 HydrophobicContact CG2-CB 4.39Å
297K94.9Very high92.9Very high22 Ų2239.9 Ų39.910%0.09618%0.181CC..EExtended strand (participates in β ladder)trans-80.9140.3171.8-65-68.9-79.3-1780110.8D255 P256 M257 S259 A262 L265 N267D255-K297 HydrophobicContact CB-CD 4.16Å; D255-K297 CarbonylContact O-C 3.57Å; D255-K297 VanDerWaalsContact O-CA 3.25Å; D255-K297 WeakPolarHBondContact O-CA 3.35Å; D255-K297 IonicContact OD2-NZ 3.06Å; D255-K297 PolarHBondContact OD2-NZ 2.82Å; P256-K297 PolarHBondContact O-NZ 2.91Å; M257-K297 HydrophobicContact CE-CB 3.72Å; M257-K297 HydrophobicContact CE-CG 4.38Å; M257-K297 HydrophobicContact SD-CB 3.84Å; M257-K297 HydrophobicContact SD-CD 4.4Å; M257-K297 WeakPolarHBondContact SD-CE 3.27Å; M257-K297 HydrophobicContact SD-CG 4.19Å; S259-K297 PolarHBondContact O-NZ 3.07Å; A262-K297 HydrophobicContact CB-CD 4.06Å; L265-K297 HydrophobicContact CB-CD 4.39Å; L265-K297 HydrophobicContact CB-CG 3.83Å; L265-K297 HydrophobicContact CD1-CG 3.86Å; N267-K297 WeakPolarHBondContact OD1-CE 3.4Å; N267-K297 PolarHBondContact OD1-NZ 3.03Å
298T92.6Very high92.4Very high3 Ų339.3 Ų39.32%0.01818%0.178CC..EExtended strand (participates in β ladder)trans-128.1144.5-178.753.60000111.5V254 D255 P256 M257 V296 A342 W345 A346V254-T298 HydrophobicContact CG1-CG2 3.47Å; V254-T298 VanDerWaalsContact CG1-CG2 3.47Å; D255-T298 PolarHBondContact O-N 3.28Å; D255-T298 PolarHBondContact O-OG1 3.48Å; P256-T298 CarbonylContact C-O 3.48Å; P256-T298 WeakPolarHBondContact CA-O 3.49Å; M257-T298 PolarHBondContact N-O 2.93Å; V296-T298 HydrophobicContact CG1-CG2 4.48Å; T298-A342 HydrophobicContact CG2-CB 4.27Å; T298-W345 HydrophobicContact CG2-CE3 3.81Å; T298-W345 HydrophobicContact CG2-CZ3 4.16Å; T298-A346 HydrophobicContact CG2-CB 4.35Å
299K89.9Confident92Very high95 Ų9539 Ų3941%0.41318%0.178SC..  trans-105.7155.3174.6-72.4-176.8-176.9-157.10109.4M257 D268 R301 E302 S303M257-K299 HydrophobicContact CB-CG 4.37Å; M257-K299 HydrophobicContact CG-CG 3.62Å; D268-K299 VanDerWaalsContact OD2-CE 3.26Å; D268-K299 WeakPolarHBondContact OD2-CE 3.45Å; D268-K299 IonicContact OD2-NZ 3.37Å; D268-K299 PolarHBondContact OD2-NZ 2.95Å; K299-R301 PolarHBondContact O-N 3.41Å; K299-E302 WeakPolarHBondContact CB-OE2 3.29Å; K299-S303 WeakPolarHBondContact O-CB 3.25Å; K299-S303 PolarHBondContact O-N 3.45Å; K299-S303 VanDerWaalsContact O-N 3.08Å; K299-S303 PolarHBondContact O-OG 2.73Å
300D86.8Confident91.7Very high24 Ų2435.6 Ų35.613%0.12817%0.165CC..Hα-helixtrans-59.9-47.8-175.3-71.8-35.2000112.1Y273 E274 V275 E302 S303 L304 W386Y273-D300 VanDerWaalsContact CA-OD2 3.31Å; Y273-D300 WeakPolarHBondContact CA-OD2 3.45Å; E274-D300 HydrophobicContact CB-CB 4.49Å; E274-D300 PolarHBondContact N-OD1 3.17Å; E274-D300 PolarHBondContact N-OD2 3.07Å; V275-D300 WeakPolarHBondContact CB-OD1 3.16Å; V275-D300 HydrophobicContact CG2-CB 4.41Å; V275-D300 WeakPolarHBondContact CG2-OD1 3Å; V275-D300 PolarHBondContact N-OD1 2.95Å; D300-E302 PolarHBondContact O-N 2.94Å; D300-S303 WeakPolarHBondContact O-CB 3.36Å; D300-S303 PolarHBondContact O-N 3.14Å; D300-S303 VanDerWaalsContact O-N 3.16Å; D300-L304 HydrophobicContact CB-CD1 4.29Å; D300-L304 WeakPolarHBondContact O-CB 3.07Å; D300-L304 WeakPolarHBondContact O-CG 3.31Å; D300-L304 PolarHBondContact O-N 3.46Å; D300-W386 HydrophobicContact CB-CH2 3.35Å; D300-W386 HydrophobicContact CB-CZ2 3.56Å; D300-W386 HydrophobicContact CB-CZ3 4.25Å
301R86.6Confident91.4Very high76 Ų7628.1 Ų28.129%0.28713%0.133SC..Hα-helixtrans-54.7-53.2-177.1-176.3178.6178.2-78.8-4.7111.8K299 S303 L304 L305 W386K299-R301 PolarHBondContact O-N 3.41Å; R301-S303 VanDerWaalsContact C-N 3.33Å; R301-S303 PolarHBondContact O-N 2.78Å; R301-L304 PolarHBondContact O-N 2.68Å; R301-L305 HydrophobicContact CG-CD1 3.86Å; R301-L305 HydrophobicContact CG-CG 4.49Å; R301-L305 VanDerWaalsContact O-CB 3.26Å; R301-L305 WeakPolarHBondContact O-CB 3.3Å; R301-L305 WeakPolarHBondContact O-CG 3.45Å; R301-L305 PolarHBondContact O-N 2.73Å; R301-W386 HydrophobicContact CB-CD2 4.39Å; R301-W386 HydrophobicContact CB-CG 4.22Å; R301-W386 HydrophobicContact CG-CB 4.43Å; R301-W386 HydrophobicContact CG-CG 4.01Å
302E88.8Confident90.8Very high54 Ų5433.1 Ų33.125%0.25215%0.152SC..Hα-helixtrans-62.7-42179.5-73.968.1-15300111.5K299 D300 T306 W345K299-E302 WeakPolarHBondContact CB-OE2 3.29Å; D300-E302 PolarHBondContact O-N 2.94Å; E302-T306 VanDerWaalsContact O-CB 3.25Å; E302-T306 WeakPolarHBondContact O-CB 3.42Å; E302-T306 PolarHBondContact O-N 2.9Å; E302-T306 PolarHBondContact O-OG1 2.81Å; E302-W345 HydrophobicContact CB-CD2 4.21Å; E302-W345 HydrophobicContact CB-CG 4.14Å; E302-W345 HydrophobicContact CB-CZ2 4.48Å; E302-W345 HydrophobicContact CG-CZ2 4.14Å
303S91.5Very high90.4Very high0 Ų035.6 Ų35.60%016%0.161CC..Hα-helixtrans-62.6-51.4179.7-59.90000110.6K299 D300 R301 T306 A307 G341 A342K299-S303 WeakPolarHBondContact O-CB 3.25Å; K299-S303 PolarHBondContact O-N 3.45Å; K299-S303 VanDerWaalsContact O-N 3.08Å; K299-S303 PolarHBondContact O-OG 2.73Å; D300-S303 WeakPolarHBondContact O-CB 3.36Å; D300-S303 PolarHBondContact O-N 3.14Å; D300-S303 VanDerWaalsContact O-N 3.16Å; R301-S303 VanDerWaalsContact C-N 3.33Å; R301-S303 PolarHBondContact O-N 2.78Å; S303-T306 PolarHBondContact O-N 3.43Å; S303-A307 PolarHBondContact O-N 2.87Å; S303-G341 CarbonylContact O-C 3.52Å; S303-G341 VanDerWaalsContact O-CA 3.25Å; S303-G341 WeakPolarHBondContact O-CA 3.49Å; S303-A342 WeakPolarHBondContact OG-CA 3.24Å; S303-A342 WeakPolarHBondContact OG-CB 3.38Å
304L89.1Confident90.2Very high0 Ų033.2 Ų33.20%015%0.148CC..Hα-helixtrans-70.8-43.3-175.7-61.8169.3000111.2V275 D300 R301 T306 A307 L308 S336 G337 F375 W380 M381 W386V275-L304 HydrophobicContact CG2-CD2 4.16Å; V275-L304 HydrophobicContact CG2-CG 4.21Å; D300-L304 HydrophobicContact CB-CD1 4.29Å; D300-L304 WeakPolarHBondContact O-CB 3.07Å; D300-L304 WeakPolarHBondContact O-CG 3.31Å; D300-L304 PolarHBondContact O-N 3.46Å; R301-L304 PolarHBondContact O-N 2.68Å; L304-T306 PolarHBondContact O-N 3.28Å; L304-A307 WeakPolarHBondContact O-CB 3.38Å; L304-A307 PolarHBondContact O-N 2.78Å; L304-L308 VanDerWaalsContact O-CB 3.26Å; L304-L308 WeakPolarHBondContact O-CB 3.3Å; L304-L308 WeakPolarHBondContact O-CG 3.2Å; L304-L308 PolarHBondContact O-N 2.96Å; L304-S336 VanDerWaalsContact CD1-OG 3.23Å; L304-S336 WeakPolarHBondContact CD1-OG 3.39Å; L304-S336 VanDerWaalsContact CD2-OG 3.3Å; L304-S336 WeakPolarHBondContact CD2-OG 3.23Å; L304-G337 WeakPolarHBondContact CD2-O 3.5Å; L304-F375 HydrophobicContact CB-CB 4.49Å; L304-F375 HydrophobicContact CD1-CB 4.46Å; L304-F375 HydrophobicContact CD2-CB 3.85Å; L304-F375 HydrophobicContact CD2-CD1 4.36Å; L304-F375 HydrophobicContact CD2-CD2 4.26Å; L304-F375 HydrophobicContact CD2-CG 3.93Å; L304-F375 HydrophobicContact CG-CB 4.49Å; L304-W380 HydrophobicContact CD1-CH2 4.21Å; L304-W380 HydrophobicContact CD1-CZ3 4.15Å; L304-M381 HydrophobicContact CB-CE 4.29Å; L304-M381 HydrophobicContact CB-SD 4.43Å; L304-W386 HydrophobicContact CD1-CE3 3.62Å; L304-W386 HydrophobicContact CD1-CH2 3.78Å; L304-W386 HydrophobicContact CD1-CZ3 3.05Å; L304-W386 HydrophobicContact CG-CZ3 4.48Å
305L86.8Confident89.8Confident41 Ų4132.3 Ų32.322%0.21516%0.162CC..Hα-helixtrans-59.8-32.1172.6-69.5176.2000112.6R301 L308 A309 M381 L387R301-L305 HydrophobicContact CG-CD1 3.86Å; R301-L305 HydrophobicContact CG-CG 4.49Å; R301-L305 VanDerWaalsContact O-CB 3.26Å; R301-L305 WeakPolarHBondContact O-CB 3.3Å; R301-L305 WeakPolarHBondContact O-CG 3.45Å; R301-L305 PolarHBondContact O-N 2.73Å; L305-L308 HydrophobicContact CD2-CD1 4.24Å; L305-L308 WeakPolarHBondContact O-CB 3.12Å; L305-A309 WeakPolarHBondContact O-CB 3.36Å; L305-A309 PolarHBondContact O-N 2.81Å; L305-M381 HydrophobicContact CD2-CE 4.29Å; L305-L387 HydrophobicContact CD2-CD2 3.96Å
306T90.2Very high89.5Confident14 Ų1431.2 Ų31.29%0.08616%0.159CC..Hα-helixtrans-76.4-39.5175.7-56.70000112.1E302 S303 L304 L308 A309 L310 M344 W345 L348E302-T306 VanDerWaalsContact O-CB 3.25Å; E302-T306 WeakPolarHBondContact O-CB 3.42Å; E302-T306 PolarHBondContact O-N 2.9Å; E302-T306 PolarHBondContact O-OG1 2.81Å; S303-T306 PolarHBondContact O-N 3.43Å; L304-T306 PolarHBondContact O-N 3.28Å; T306-L308 VanDerWaalsContact C-N 3.27Å; T306-L308 PolarHBondContact O-N 3.14Å; T306-A309 PolarHBondContact O-N 3.34Å; T306-A309 VanDerWaalsContact O-N 3.12Å; T306-L310 PolarHBondContact O-N 3.48Å; T306-M344 HydrophobicContact CG2-CB 3.82Å; T306-M344 HydrophobicContact CG2-CG 3.75Å; T306-W345 HydrophobicContact CG2-CB 4.1Å; T306-L348 HydrophobicContact CG2-CD1 4.39Å
307A91Very high89.1Confident0 Ų034.5 Ų34.50%018%0.175CC..Hα-helixtrans-55.6-50.2170.900000109.4S303 L304 A309 L310 I311 F375S303-A307 PolarHBondContact O-N 2.87Å; L304-A307 WeakPolarHBondContact O-CB 3.38Å; L304-A307 PolarHBondContact O-N 2.78Å; A307-A309 VanDerWaalsContact C-N 3.29Å; A307-A309 PolarHBondContact O-N 3.31Å; A307-L310 WeakPolarHBondContact O-CB 3.22Å; A307-L310 PolarHBondContact O-N 3.38Å; A307-L310 VanDerWaalsContact O-N 3.11Å; A307-I311 WeakPolarHBondContact O-CD1 3.42Å; A307-I311 WeakPolarHBondContact O-CG1 3.33Å; A307-I311 PolarHBondContact O-N 2.99Å; A307-F375 HydrophobicContact CB-CD2 4.49Å; A307-F375 HydrophobicContact CB-CE2 3.69Å; A307-F375 HydrophobicContact CB-CZ 4.2Å
308L86.6Confident87.9Confident1 Ų133.7 Ų33.71%0.00517%0.172CC..Hα-helixtrans-53.7-41.6174.1-73.1178.4000113.2L304 L305 T306 R312 L320 Y321 F375 M381L304-L308 VanDerWaalsContact O-CB 3.26Å; L304-L308 WeakPolarHBondContact O-CB 3.3Å; L304-L308 WeakPolarHBondContact O-CG 3.2Å; L304-L308 PolarHBondContact O-N 2.96Å; L305-L308 HydrophobicContact CD2-CD1 4.24Å; L305-L308 WeakPolarHBondContact O-CB 3.12Å; T306-L308 VanDerWaalsContact C-N 3.27Å; T306-L308 PolarHBondContact O-N 3.14Å; L308-R312 PolarHBondContact O-N 3.24Å; L308-L320 WeakPolarHBondContact CD2-O 3.47Å; L308-Y321 VanDerWaalsContact CB-CB 3.44Å; L308-Y321 HydrophobicContact CB-CD1 4.19Å; L308-Y321 HydrophobicContact CB-CD2 3.69Å; L308-Y321 HydrophobicContact CB-CE2 4.44Å; L308-Y321 HydrophobicContact CB-CG 3.52Å; L308-Y321 HydrophobicContact CD1-CD2 3.57Å; L308-Y321 HydrophobicContact CD1-CE2 4.03Å; L308-Y321 HydrophobicContact CD1-CG 4.3Å; L308-Y321 VanDerWaalsContact CD2-CB 3.42Å; L308-Y321 HydrophobicContact CD2-CD2 3.81Å; L308-Y321 HydrophobicContact CD2-CG 4Å; L308-Y321 HydrophobicContact CG-CD2 3.85Å; L308-Y321 HydrophobicContact CG-CG 4.1Å; L308-Y321 WeakPolarHBondContact O-CB 3.34Å; L308-F375 HydrophobicContact CD2-CD2 3.69Å; L308-F375 HydrophobicContact CD2-CE2 4.05Å; L308-F375 HydrophobicContact CG-CD2 3.97Å; L308-F375 HydrophobicContact CG-CE2 4.38Å; L308-M381 HydrophobicContact CD1-CE 3.59Å; L308-M381 HydrophobicContact CD1-SD 4.29Å
309A87.2Confident85.6Confident16 Ų1633.5 Ų33.513%0.13217%0.171CC..Hα-helixtrans-69.5-36.8177.100000113.3L69 L305 T306 A307 I311 R312 K313L69-A309 HydrophobicContact CD2-CB 3.88Å; L305-A309 WeakPolarHBondContact O-CB 3.36Å; L305-A309 PolarHBondContact O-N 2.81Å; T306-A309 PolarHBondContact O-N 3.34Å; T306-A309 VanDerWaalsContact O-N 3.12Å; A307-A309 VanDerWaalsContact C-N 3.29Å; A307-A309 PolarHBondContact O-N 3.31Å; A309-I311 VanDerWaalsContact C-N 3.26Å; A309-I311 PolarHBondContact O-N 3.38Å; A309-R312 PolarHBondContact O-N 3.19Å; A309-K313 VanDerWaalsContact O-CB 3.24Å; A309-K313 WeakPolarHBondContact O-CB 3.47Å; A309-K313 WeakPolarHBondContact O-CG 3.49Å; A309-K313 PolarHBondContact O-N 3.37Å
310L89.4Confident82.7Confident0 Ų033 Ų330%017%0.172CC..Hα-helixtrans-56-43175.9-81.8163.5000111.3I66 L69 T306 A307 E314 G315 I316 C318 M344 L364I66-L310 HydrophobicContact CD1-CD2 3.97Å; L69-L310 HydrophobicContact CD1-CB 4.45Å; L69-L310 HydrophobicContact CD1-CD2 3.68Å; L69-L310 HydrophobicContact CD1-CG 3.87Å; T306-L310 PolarHBondContact O-N 3.48Å; A307-L310 WeakPolarHBondContact O-CB 3.22Å; A307-L310 PolarHBondContact O-N 3.38Å; A307-L310 VanDerWaalsContact O-N 3.11Å; L310-E314 HydrophobicContact CD2-CG 4.48Å; L310-E314 WeakPolarHBondContact O-CA 3.29Å; L310-E314 VanDerWaalsContact O-CB 3.22Å; L310-E314 WeakPolarHBondContact O-CB 3.29Å; L310-E314 PolarHBondContact O-N 2.85Å; L310-G315 PolarHBondContact O-N 3.03Å; L310-I316 HydrophobicContact CD2-CD1 4.42Å; L310-C318 WeakPolarHBondContact CD1-SG 3.41Å; L310-M344 HydrophobicContact CD1-CB 3.74Å; L310-M344 HydrophobicContact CD1-CG 3.86Å; L310-M344 HydrophobicContact CD2-CE 4.2Å; L310-M344 HydrophobicContact CD2-CG 3.94Å; L310-M344 HydrophobicContact CD2-SD 4.07Å; L310-M344 HydrophobicContact CG-CB 4.42Å; L310-M344 HydrophobicContact CG-CG 3.99Å; L310-L364 HydrophobicContact CD1-CD2 4.3Å
311I88.5Confident80.1Confident12 Ų1234 Ų346%0.06218%0.175CC..Hα-helixtrans-75.8-46.5-174.5-42.3116.8000110.4A307 A309 K313 G315 I316 L317 G319 L320A307-I311 WeakPolarHBondContact O-CD1 3.42Å; A307-I311 WeakPolarHBondContact O-CG1 3.33Å; A307-I311 PolarHBondContact O-N 2.99Å; A309-I311 VanDerWaalsContact C-N 3.26Å; A309-I311 PolarHBondContact O-N 3.38Å; I311-K313 VanDerWaalsContact C-N 3.29Å; I311-K313 PolarHBondContact O-N 3.48Å; I311-G315 VanDerWaalsContact O-CA 3.25Å; I311-G315 WeakPolarHBondContact O-CA 3.32Å; I311-G315 PolarHBondContact O-N 2.94Å; I311-I316 VanDerWaalsContact CA-O 3.29Å; I311-I316 WeakPolarHBondContact CA-O 3.39Å; I311-I316 WeakPolarHBondContact CB-O 3.31Å; I311-I316 WeakPolarHBondContact CG1-O 3.48Å; I311-L317 HydrophobicContact CG2-CD2 3.6Å; I311-L317 HydrophobicContact CG2-CG 4.44Å; I311-G319 WeakPolarHBondContact CD1-O 3.23Å; I311-G319 WeakPolarHBondContact CG1-O 3.46Å; I311-L320 HydrophobicContact CB-CB 4.17Å; I311-L320 HydrophobicContact CD1-CB 3.95Å; I311-L320 HydrophobicContact CG1-CB 4.25Å; I311-L320 HydrophobicContact CG2-CB 3.78Å; I311-L320 HydrophobicContact CG2-CD1 3.85Å; I311-L320 HydrophobicContact CG2-CG 4.42Å
312R84.3Confident77.4Confident105 Ų10535.6 Ų35.640%0.39619%0.185SC..Hα-helixtrans-63.1-39.2-178-177.7174.3-173.584.52.7111.7L308 A309 Y321 H322L308-R312 PolarHBondContact O-N 3.24Å; A309-R312 PolarHBondContact O-N 3.19Å; R312-Y321 HydrophobicContact CB-CD1 4.08Å; R312-Y321 HydrophobicContact CG-CD1 4.43Å; R312-H322 PolarHBondContact NH1-CD2 3.45Å; R312-H322 PolarHBondContact NH1-CE1 2.93Å; R312-H322 PolarHBondContact NH1-NE2 3.46Å
313K89Confident74.7Confident67 Ų6741.8 Ų41.829%0.29121%0.206SC..Hα-helixtrans-97.5-33.2-170.5-62-177.9-179.5-178.60112.9R68 L69 E72 A309 I311R68-K313 HydrophobicContact CB-CB 4.31Å; R68-K313 VanDerWaalsContact CD-O 3.31Å; R68-K313 WeakPolarHBondContact CD-O 3.19Å; R68-K313 PolarHBondContact NH1-O 3.46Å; L69-K313 HydrophobicContact CD2-CD 3.66Å; L69-K313 HydrophobicContact CG-CB 4.42Å; L69-K313 HydrophobicContact CG-CD 4.27Å; E72-K313 IonicContact OE1-NZ 3.33Å; E72-K313 PolarHBondContact OE1-NZ 3.45Å; E72-K313 WeakPolarHBondContact OE2-CD 3.33Å; E72-K313 IonicContact OE2-NZ 2.77Å; E72-K313 PolarHBondContact OE2-NZ 2.82Å; A309-K313 VanDerWaalsContact O-CB 3.24Å; A309-K313 WeakPolarHBondContact O-CB 3.47Å; A309-K313 WeakPolarHBondContact O-CG 3.49Å; A309-K313 PolarHBondContact O-N 3.37Å; I311-K313 VanDerWaalsContact C-N 3.29Å; I311-K313 PolarHBondContact O-N 3.48Å
314E91.2Very high72Confident36 Ų3642.6 Ų42.617%0.16821%0.213CC..Hα-helixtrans-112.8-6-175.3-48.9-67.5166.800113I66 N67 R68 L69 L310 I316I66-E314 HydrophobicContact CD1-CB 4.44Å; I66-E314 HydrophobicContact CD1-CG 3.99Å; I66-E314 HydrophobicContact CG2-CG 4.23Å; I66-E314 WeakPolarHBondContact CG2-OE1 3.29Å; N67-E314 PolarHBondContact N-OE1 3.03Å; N67-E314 PolarHBondContact N-OE2 3.39Å; R68-E314 VanDerWaalsContact CA-OE1 3.31Å; R68-E314 WeakPolarHBondContact CA-OE1 3.33Å; R68-E314 WeakPolarHBondContact CB-OE1 3.41Å; R68-E314 PolarHBondContact N-OE1 2.87Å; L69-E314 HydrophobicContact CD1-CG 4.16Å; L69-E314 HydrophobicContact CG-CG 4.37Å; L69-E314 PolarHBondContact N-OE1 3.47Å; L310-E314 HydrophobicContact CD2-CG 4.48Å; L310-E314 WeakPolarHBondContact O-CA 3.29Å; L310-E314 VanDerWaalsContact O-CB 3.22Å; L310-E314 WeakPolarHBondContact O-CB 3.29Å; L310-E314 PolarHBondContact O-N 2.85Å; E314-I316 HydrophobicContact CB-CB 4.4Å; E314-I316 HydrophobicContact CB-CD1 3.7Å; E314-I316 HydrophobicContact CB-CG1 3.76Å; E314-I316 HydrophobicContact CG-CD1 4.49Å; E314-I316 PolarHBondContact O-N 3.22Å
315G88.1Confident69.3Low59 Ų5950.1 Ų50.161%0.60825%0.248SC*.  trans68.818.4-176.400000113.4L310 I311L310-G315 PolarHBondContact O-N 3.03Å; I311-G315 VanDerWaalsContact O-CA 3.25Å; I311-G315 WeakPolarHBondContact O-CA 3.32Å; I311-G315 PolarHBondContact O-N 2.94Å
316I90.4Very high66.9Low8 Ų858 Ų584%0.04128%0.275CS..  trans-91.6107.4-176.5-65.7179.7000108I66 V81 Y85 L310 I311 E314 C318 L364I66-I316 HydrophobicContact CD1-CD1 3.53Å; V81-I316 HydrophobicContact CG2-CD1 3.78Å; Y85-I316 HydrophobicContact CE1-CG2 3.94Å; Y85-I316 VanDerWaalsContact OH-CG2 3.23Å; Y85-I316 WeakPolarHBondContact OH-CG2 3.22Å; L310-I316 HydrophobicContact CD2-CD1 4.42Å; I311-I316 VanDerWaalsContact CA-O 3.29Å; I311-I316 WeakPolarHBondContact CA-O 3.39Å; I311-I316 WeakPolarHBondContact CB-O 3.31Å; I311-I316 WeakPolarHBondContact CG1-O 3.48Å; E314-I316 HydrophobicContact CB-CB 4.4Å; E314-I316 HydrophobicContact CB-CD1 3.7Å; E314-I316 HydrophobicContact CB-CG1 3.76Å; E314-I316 HydrophobicContact CG-CD1 4.49Å; E314-I316 PolarHBondContact O-N 3.22Å; I316-C318 HydrophobicContact CG2-CB 4.12Å; I316-C318 WeakPolarHBondContact CG2-SG 3.42Å; I316-C318 PolarHBondContact O-N 3.2Å; I316-L364 HydrophobicContact CG2-CD1 3.64Å
317L88.2Confident64.4Low91 Ų9160.1 Ų60.148%0.47629%0.29SS..  trans-76.461-179.2-68.1171.6000111.7I311 L320 V368I311-L317 HydrophobicContact CG2-CD2 3.6Å; I311-L317 HydrophobicContact CG2-CG 4.44Å; L317-L320 HydrophobicContact CD2-CD1 4.23Å; L317-V368 HydrophobicContact CB-CG1 3.69Å; L317-V368 HydrophobicContact CD2-CG1 4.22Å; L317-V368 WeakPolarHBondContact O-CG1 3.3Å; L317-V368 PolarHBondContact O-N 3Å
318C68.9Low61.7Low5 Ų566.2 Ų66.23%0.03432%0.323CS..SBendtrans-109.233165.4650000110.4Y85 L310 I316Y85-C318 HydrophobicContact CD1-CB 4.26Å; Y85-C318 HydrophobicContact CE1-CB 4.18Å; L310-C318 WeakPolarHBondContact CD1-SG 3.41Å; I316-C318 HydrophobicContact CG2-CB 4.12Å; I316-C318 WeakPolarHBondContact CG2-SG 3.42Å; I316-C318 PolarHBondContact O-N 3.2Å
319G46.3Very low59.2Low0 Ų074.7 Ų74.70%036%0.363CS..SBendtrans160.7-164169.300000112.3I311 V368I311-G319 WeakPolarHBondContact CD1-O 3.23Å; I311-G319 WeakPolarHBondContact CG1-O 3.46Å; G319-V368 VanDerWaalsContact N-CG1 3.34Å; G319-V368 WeakPolarHBondContact O-CG1 3.49Å
320L28.5Very low56.9Low83 Ų8381.2 Ų81.244%0.43539%0.394SS..  trans-143.8110.2178.7174.8173.6000114.4L308 I311 L317 L376L308-L320 WeakPolarHBondContact CD2-O 3.47Å; I311-L320 HydrophobicContact CB-CB 4.17Å; I311-L320 HydrophobicContact CD1-CB 3.95Å; I311-L320 HydrophobicContact CG1-CB 4.25Å; I311-L320 HydrophobicContact CG2-CB 3.78Å; I311-L320 HydrophobicContact CG2-CD1 3.85Å; I311-L320 HydrophobicContact CG2-CG 4.42Å; L317-L320 HydrophobicContact CD2-CD1 4.23Å; L320-L376 HydrophobicContact CB-CD2 3.74Å; L320-L376 HydrophobicContact CB-CG 4.46Å; L320-L376 HydrophobicContact CD2-CD2 3.76Å; L320-L376 HydrophobicContact CG-CD2 4.35Å; L320-L376 WeakPolarHBondContact O-CA 3.32Å
321Y32.6Very low54.1Low46 Ų4688 Ų8818%0.1843%0.426CS..  trans-124.9146.5178.4-172-131.8000119.6L308 R312 R323 A324 L387L308-Y321 VanDerWaalsContact CB-CB 3.44Å; L308-Y321 HydrophobicContact CB-CD1 4.19Å; L308-Y321 HydrophobicContact CB-CD2 3.69Å; L308-Y321 HydrophobicContact CB-CE2 4.44Å; L308-Y321 HydrophobicContact CB-CG 3.52Å; L308-Y321 HydrophobicContact CD1-CD2 3.57Å; L308-Y321 HydrophobicContact CD1-CE2 4.03Å; L308-Y321 HydrophobicContact CD1-CG 4.3Å; L308-Y321 VanDerWaalsContact CD2-CB 3.42Å; L308-Y321 HydrophobicContact CD2-CD2 3.81Å; L308-Y321 HydrophobicContact CD2-CG 4Å; L308-Y321 HydrophobicContact CG-CD2 3.85Å; L308-Y321 HydrophobicContact CG-CG 4.1Å; L308-Y321 WeakPolarHBondContact O-CB 3.34Å; R312-Y321 HydrophobicContact CB-CD1 4.08Å; R312-Y321 HydrophobicContact CG-CD1 4.43Å; Y321-R323 WeakPolarHBondContact OH-CA 3.44Å; Y321-A324 PolarHBondContact OH-N 3.08Å; Y321-A324 VanDerWaalsContact OH-N 3.09Å; Y321-L387 HydrophobicContact CE2-CD1 4.03Å; Y321-L387 HydrophobicContact CE2-CD2 3.9Å
322H29.7Very low51.3Low110 Ų11089.6 Ų89.651%0.50945%0.446SS..  trans-138.9150.8149.2-140.9-81.1000113.7R312R312-H322 PolarHBondContact NH1-CD2 3.45Å; R312-H322 PolarHBondContact NH1-CE1 2.93Å; R312-H322 PolarHBondContact NH1-NE2 3.46Å
323R31.2Very low48.6Very low184 Ų18489.2 Ų89.269%0.69446%0.455SS*.  trans-60.9135.9-156.8-164.6-179-171.9172.21120.4Y321Y321-R323 WeakPolarHBondContact OH-CA 3.44Å
324A35.6Very low45.7Very low17 Ų1791.7 Ų91.714%0.1447%0.471CS..  trans-174.6160.5136.500000114.7Y321 L387 Q390Y321-A324 PolarHBondContact OH-N 3.08Å; Y321-A324 VanDerWaalsContact OH-N 3.09Å; A324-L387 VanDerWaalsContact O-CD2 3.29Å; A324-L387 WeakPolarHBondContact O-CD2 3.19Å; A324-Q390 HydrophobicContact CB-CG 3.96Å
325Q32.2Very low42.8Very low158 Ų15890.2 Ų90.274%0.73846%0.464SS*.  trans-112.3159.6-166.6-73.7-174.8-36.700114.7S388Q325-S388 PolarHBondContact O-OG 3.23Å; Q325-S388 VanDerWaalsContact O-OG 3.09Å
326R35.3Very low39.9Very low207 Ų20787.4 Ų87.478%0.78144%0.435SS*.  trans65.1108.6168.1-76.8-176.7170.2173.6-4.1116.6
327S37.5Very low38Very low58 Ų5887 Ų8741%0.40643%0.434SS..  67.7120.388.5850000110.5
328D36.3Very low37.2Very low127 Ų12782.8 Ų82.868%0.67941%0.412SS*.  -158.6156.454.1-45.1-44.2000111.5
329E32.7Very low38.2Very low180 Ų18082.8 Ų82.884%0.84141%0.412SS*.  trans18.5120.6162.4-61.7174.6176.200122.8
330L39.7Very low40.5Very low152 Ų15282.9 Ų82.980%0.79641%0.412SS*.  -178.6158.8112.2-134.881000112.8
331E30.1Very low43.6Very low143 Ų14378.9 Ų78.967%0.66839%0.392SS*.  trans-84.4135.1-169.9-142.7170.1-173.700113
332G29.6Very low46.6Very low46 Ų4676.7 Ų76.747%0.47438%0.383SS..  trans175.4103.4178.500000116.9
333T27.4Very low49.8Very low97 Ų9771.5 Ų71.560%0.59536%0.359SS*.  trans-12.8121.7170.8-31.90000120.5F272 R384F272-T333 HydrophobicContact CZ-CG2 4.43Å; T333-R384 VanDerWaalsContact C-NH2 3.3Å; T333-R384 PolarHBondContact O-NH2 2.93Å
334L28.5Very low52.9Low119 Ų11962.8 Ų62.862%0.62333%0.326SS*.  trans162.385.1138.9-97.2138.4000110.5E274 W380 R384E274-L334 PolarHBondContact OE1-N 3.29Å; E274-L334 PolarHBondContact OE2-N 2.67Å; L334-W380 WeakPolarHBondContact O-CZ2 3.19Å; L334-W380 PolarHBondContact O-NE1 2.84Å; L334-R384 VanDerWaalsContact CA-NH2 3.33Å; L334-R384 PolarHBondContact O-NH2 3.36Å; L334-R384 VanDerWaalsContact O-NH2 3.11Å
335T29.2Very low55.8Low4 Ų465 Ų653%0.02533%0.331CS..  trans-5.8144.3178.137.60000121.4K146 E274 E276 K374K146-T335 HydrophobicContact CB-CG2 3.59Å; K146-T335 HydrophobicContact CD-CG2 3.79Å; K146-T335 HydrophobicContact CG-CG2 3.68Å; K146-T335 WeakPolarHBondContact O-CB 3.21Å; K146-T335 WeakPolarHBondContact O-CG2 3.41Å; K146-T335 PolarHBondContact O-OG1 3.47Å; E274-T335 WeakPolarHBondContact OE2-CA 3.09Å; E274-T335 PolarHBondContact OE2-N 3.45Å; E276-T335 HydrophobicContact CG-CG2 3.83Å; E276-T335 WeakPolarHBondContact OE1-CB 3.39Å; T335-K374 VanDerWaalsContact C-NZ 3.32Å; T335-K374 WeakPolarHBondContact O-CD 3.32Å; T335-K374 WeakPolarHBondContact O-CE 3.33Å; T335-K374 WeakPolarHBondContact O-CG 3.28Å; T335-K374 PolarHBondContact O-NZ 2.89Å; T335-K374 PolarHBondContact OG1-NZ 3.42Å
336S28.4Very low58.9Low0 Ų057.5 Ų57.50%030%0.296CS..EExtended strand (participates in β ladder)trans-142.2152.1167.1620000114.6E274 V275 E276 L304 W380E274-S336 CarbonylContact C-O 3.49Å; E274-S336 CarbonylContact O-C 3.45Å; E274-S336 PolarHBondContact O-N 2.79Å; V275-S336 CarbonylContact C-O 3.51Å; V275-S336 WeakPolarHBondContact CA-O 3.33Å; E276-S336 WeakPolarHBondContact CG-O 3.36Å; E276-S336 PolarHBondContact N-O 2.62Å; L304-S336 VanDerWaalsContact CD1-OG 3.23Å; L304-S336 WeakPolarHBondContact CD1-OG 3.39Å; L304-S336 VanDerWaalsContact CD2-OG 3.3Å; L304-S336 WeakPolarHBondContact CD2-OG 3.23Å; S336-W380 VanDerWaalsContact CB-CZ2 3.47Å; S336-W380 WeakPolarHBondContact OG-CH2 3.44Å
337G49.2Very low61.8Low1 Ų147.7 Ų47.71%0.0126%0.259CS..EExtended strand (participates in β ladder)trans-73.1131.9170.100000112.8L304 Y371 F375L304-G337 WeakPolarHBondContact CD2-O 3.5Å; G337-Y371 VanDerWaalsContact CA-CE2 3.47Å; G337-Y371 VanDerWaalsContact CA-CG 3.46Å; G337-F375 WeakPolarHBondContact O-CD1 3.45Å; G337-F375 WeakPolarHBondContact O-CE1 3.41Å; G337-F375 WeakPolarHBondContact O-CZ 3.29Å
338G72.4Confident64.6Low2 Ų245.8 Ų45.82%0.02124%0.244CC..  trans-158.94.2178.200000114.2S340 G341 A342G338-S340 VanDerWaalsContact C-N 3.26Å; G338-S340 PolarHBondContact O-N 2.99Å; G338-G341 CarbonylContact O-C 3.54Å; G338-G341 VanDerWaalsContact O-CA 3.31Å; G338-G341 WeakPolarHBondContact O-CA 3.3Å; G338-G341 PolarHBondContact O-N 2.81Å; G338-A342 PolarHBondContact O-N 3.1Å
339S90.7Very high67.4Low4 Ų443.2 Ų43.23%0.02823%0.228CC..Hα-helixtrans-61.1-34.3-17365.10000112.8G341 A342 N343 P365S339-G341 VanDerWaalsContact C-N 3.34Å; S339-G341 PolarHBondContact O-N 2.9Å; S339-A342 PolarHBondContact O-N 3.24Å; S339-N343 WeakPolarHBondContact O-CB 3.4Å; S339-N343 PolarHBondContact O-N 3.11Å; S339-N343 PolarHBondContact O-OD1 3.23Å; S339-P365 WeakPolarHBondContact OG-CG 3.18Å
340S94.6Very high70.5Confident2 Ų234.9 Ų34.91%0.01419%0.19CC..Hα-helixtrans-59.4-43.1169.4-70.80000112.3G338 M344 P365G338-S340 VanDerWaalsContact C-N 3.26Å; G338-S340 PolarHBondContact O-N 2.99Å; S340-M344 VanDerWaalsContact O-CB 3.28Å; S340-M344 WeakPolarHBondContact O-CB 3.47Å; S340-M344 PolarHBondContact O-N 3.2Å; S340-P365 VanDerWaalsContact OG-CD 3.24Å; S340-P365 WeakPolarHBondContact OG-CD 3.46Å
341G93.6Very high73.2Confident0 Ų027.6 Ų27.60%015%0.152CC..Hα-helixtrans-70.3-38.4175.900000113.6S303 G338 S339 M344 W345S303-G341 CarbonylContact O-C 3.52Å; S303-G341 VanDerWaalsContact O-CA 3.25Å; S303-G341 WeakPolarHBondContact O-CA 3.49Å; G338-G341 CarbonylContact O-C 3.54Å; G338-G341 VanDerWaalsContact O-CA 3.31Å; G338-G341 WeakPolarHBondContact O-CA 3.3Å; G338-G341 PolarHBondContact O-N 2.81Å; S339-G341 VanDerWaalsContact C-N 3.34Å; S339-G341 PolarHBondContact O-N 2.9Å; G341-M344 PolarHBondContact O-N 2.81Å; G341-W345 VanDerWaalsContact O-CB 3.28Å; G341-W345 WeakPolarHBondContact O-CB 3.43Å; G341-W345 PolarHBondContact O-N 3.44Å
342A94.9Very high76.4Confident0 Ų026.4 Ų26.40%014%0.144CC..Hα-helixtrans-60.6-49.117300000111V254 I278 T298 S303 G338 S339 M344 W345 A346V254-A342 HydrophobicContact CG1-CB 4.36Å; I278-A342 HydrophobicContact CD1-CB 3.8Å; T298-A342 HydrophobicContact CG2-CB 4.27Å; S303-A342 WeakPolarHBondContact OG-CA 3.24Å; S303-A342 WeakPolarHBondContact OG-CB 3.38Å; G338-A342 PolarHBondContact O-N 3.1Å; S339-A342 PolarHBondContact O-N 3.24Å; A342-M344 VanDerWaalsContact C-N 3.33Å; A342-M344 PolarHBondContact O-N 3.5Å; A342-W345 PolarHBondContact O-N 2.96Å; A342-A346 WeakPolarHBondContact O-CB 3.35Å; A342-A346 PolarHBondContact O-N 2.76Å
343N97.2Very high79.4Confident1 Ų129.7 Ų29.71%0.00515%0.151CC..Hα-helixtrans-61.1-43.6177.6-67.6-4.5000111.6V226 G228 S339 A347 V362 L363V226-N343 WeakPolarHBondContact CG1-O 3.46Å; G228-N343 WeakPolarHBondContact CA-OD1 3.38Å; G228-N343 VanDerWaalsContact N-CG 3.33Å; G228-N343 PolarHBondContact N-ND2 3.27Å; G228-N343 PolarHBondContact N-OD1 2.88Å; S339-N343 WeakPolarHBondContact O-CB 3.4Å; S339-N343 PolarHBondContact O-N 3.11Å; S339-N343 PolarHBondContact O-OD1 3.23Å; N343-A347 WeakPolarHBondContact O-CB 3.41Å; N343-A347 PolarHBondContact O-N 3.22Å; N343-V362 HydrophobicContact CB-CG1 3.77Å; N343-L363 PolarHBondContact ND2-O 2.75Å
344M96.5Very high82.7Confident0 Ų025.6 Ų25.60%013%0.125CC..Hα-helixtrans-67.3-43.4178.6-173.966.6-175.600112.1I66 L69 L79 V81 T306 L310 S340 G341 A342 A346 A347 L348 V362I66-M344 HydrophobicContact CG1-CE 4.13Å; I66-M344 HydrophobicContact CG2-CE 3.85Å; L69-M344 HydrophobicContact CB-CE 3.96Å; L69-M344 HydrophobicContact CD1-CE 3.95Å; L79-M344 HydrophobicContact CD2-CE 3.38Å; L79-M344 HydrophobicContact CD2-SD 4.24Å; L79-M344 HydrophobicContact CG-CE 4.35Å; V81-M344 HydrophobicContact CG1-SD 4.37Å; T306-M344 HydrophobicContact CG2-CB 3.82Å; T306-M344 HydrophobicContact CG2-CG 3.75Å; L310-M344 HydrophobicContact CD1-CB 3.74Å; L310-M344 HydrophobicContact CD1-CG 3.86Å; L310-M344 HydrophobicContact CD2-CE 4.2Å; L310-M344 HydrophobicContact CD2-CG 3.94Å; L310-M344 HydrophobicContact CD2-SD 4.07Å; L310-M344 HydrophobicContact CG-CB 4.42Å; L310-M344 HydrophobicContact CG-CG 3.99Å; S340-M344 VanDerWaalsContact O-CB 3.28Å; S340-M344 WeakPolarHBondContact O-CB 3.47Å; S340-M344 PolarHBondContact O-N 3.2Å; G341-M344 PolarHBondContact O-N 2.81Å; A342-M344 VanDerWaalsContact C-N 3.33Å; A342-M344 PolarHBondContact O-N 3.5Å; M344-A346 VanDerWaalsContact C-N 3.32Å; M344-A346 PolarHBondContact O-N 3.35Å; M344-A347 WeakPolarHBondContact O-CB 3.2Å; M344-A347 PolarHBondContact O-N 3.31Å; M344-L348 HydrophobicContact CE-CD1 4.42Å; M344-L348 HydrophobicContact CE-CD2 3.91Å; M344-L348 HydrophobicContact CE-CG 4.14Å; M344-L348 HydrophobicContact CG-CD1 4.49Å; M344-L348 VanDerWaalsContact O-CG 3.31Å; M344-L348 WeakPolarHBondContact O-CG 3.09Å; M344-L348 PolarHBondContact O-N 3.33Å; M344-V362 HydrophobicContact SD-CG2 4.47Å
345W95.5Very high86Confident65 Ų6527.1 Ų27.125%0.24613%0.127CC..Hα-helixtrans-61-45.7177.4-176.790.9000110.5V296 T298 E302 T306 G341 A342 A347 L348 Q349V296-W345 HydrophobicContact CG1-CE3 4.46Å; V296-W345 HydrophobicContact CG1-CZ3 3.93Å; T298-W345 HydrophobicContact CG2-CE3 3.81Å; T298-W345 HydrophobicContact CG2-CZ3 4.16Å; E302-W345 HydrophobicContact CB-CD2 4.21Å; E302-W345 HydrophobicContact CB-CG 4.14Å; E302-W345 HydrophobicContact CB-CZ2 4.48Å; E302-W345 HydrophobicContact CG-CZ2 4.14Å; T306-W345 HydrophobicContact CG2-CB 4.1Å; G341-W345 VanDerWaalsContact O-CB 3.28Å; G341-W345 WeakPolarHBondContact O-CB 3.43Å; G341-W345 PolarHBondContact O-N 3.44Å; A342-W345 PolarHBondContact O-N 2.96Å; W345-A347 VanDerWaalsContact C-N 3.31Å; W345-A347 PolarHBondContact O-N 3.18Å; W345-L348 PolarHBondContact O-N 3.2Å; W345-Q349 HydrophobicContact CD2-CG 4.17Å; W345-Q349 HydrophobicContact CE3-CG 4.05Å; W345-Q349 HydrophobicContact CH2-CG 3.86Å; W345-Q349 HydrophobicContact CZ2-CG 3.96Å; W345-Q349 HydrophobicContact CZ3-CG 3.9Å; W345-Q349 WeakPolarHBondContact O-CG 3.47Å; W345-Q349 PolarHBondContact O-N 2.75Å; W345-Q349 VanDerWaalsContact O-N 3.11Å
346A96.9Very high89.2Confident0 Ų035 Ų350%016%0.164CC..Hα-helixtrans-59.9-41.4175.600000111.8V226 V254 V296 T298 A342 M344 Q349 A350V226-A346 HydrophobicContact CG1-CB 4.21Å; V254-A346 HydrophobicContact CB-CB 4.29Å; V254-A346 HydrophobicContact CG1-CB 3.86Å; V254-A346 HydrophobicContact CG2-CB 3.43Å; V254-A346 VanDerWaalsContact CG2-CB 3.43Å; V296-A346 HydrophobicContact CB-CB 3.91Å; V296-A346 HydrophobicContact CG1-CB 3.7Å; V296-A346 HydrophobicContact CG2-CB 4.39Å; T298-A346 HydrophobicContact CG2-CB 4.35Å; A342-A346 WeakPolarHBondContact O-CB 3.35Å; A342-A346 PolarHBondContact O-N 2.76Å; M344-A346 VanDerWaalsContact C-N 3.32Å; M344-A346 PolarHBondContact O-N 3.35Å; A346-Q349 PolarHBondContact O-N 3.5Å; A346-A350 WeakPolarHBondContact O-CB 3.27Å; A346-A350 PolarHBondContact O-N 2.89Å
347A97.5Very high92.5Very high0 Ų038.3 Ų38.30%020%0.197CC..Hα-helixtrans-63.6-41.7175.400000112.7L79 V226 N343 M344 W345 Q349 A350 A351 V362L79-A347 HydrophobicContact CD1-CB 4.45Å; V226-A347 HydrophobicContact CB-CB 4.1Å; V226-A347 HydrophobicContact CG1-CB 4.14Å; V226-A347 HydrophobicContact CG2-CB 3.82Å; N343-A347 WeakPolarHBondContact O-CB 3.41Å; N343-A347 PolarHBondContact O-N 3.22Å; M344-A347 WeakPolarHBondContact O-CB 3.2Å; M344-A347 PolarHBondContact O-N 3.31Å; W345-A347 VanDerWaalsContact C-N 3.31Å; W345-A347 PolarHBondContact O-N 3.18Å; A347-Q349 PolarHBondContact O-N 3.35Å; A347-A350 PolarHBondContact O-N 3.3Å; A347-A351 WeakPolarHBondContact O-CB 3.47Å; A347-A351 PolarHBondContact O-N 3.26Å; A347-V362 HydrophobicContact CB-CB 4.41Å; A347-V362 HydrophobicContact CB-CG1 4.23Å; A347-V362 HydrophobicContact CB-CG2 3.3Å
348L96.3Very high94.8Very high18 Ų1840.7 Ų40.79%0.09421%0.208CC..Hα-helixtrans-63.2-27.8176.1-67.9177.1000112.7A73 L75 L79 T306 M344 W345 K352A73-L348 HydrophobicContact CB-CB 4.47Å; A73-L348 HydrophobicContact CB-CD2 3.78Å; L75-L348 HydrophobicContact CD1-CD2 3.88Å; L79-L348 HydrophobicContact CD2-CD2 3.89Å; T306-L348 HydrophobicContact CG2-CD1 4.39Å; M344-L348 HydrophobicContact CE-CD1 4.42Å; M344-L348 HydrophobicContact CE-CD2 3.91Å; M344-L348 HydrophobicContact CE-CG 4.14Å; M344-L348 HydrophobicContact CG-CD1 4.49Å; M344-L348 VanDerWaalsContact O-CG 3.31Å; M344-L348 WeakPolarHBondContact O-CG 3.09Å; M344-L348 PolarHBondContact O-N 3.33Å; W345-L348 PolarHBondContact O-N 3.2Å; L348-K352 WeakPolarHBondContact O-CE 3.22Å
349Q95.2Very high96.1Very high73 Ų7342.3 Ų42.334%0.34122%0.215SC..Hα-helixtrans-80.6-49.5171.2-55.7-44.9-43.100111.8W345 A346 A347 K352W345-Q349 HydrophobicContact CD2-CG 4.17Å; W345-Q349 HydrophobicContact CE3-CG 4.05Å; W345-Q349 HydrophobicContact CH2-CG 3.86Å; W345-Q349 HydrophobicContact CZ2-CG 3.96Å; W345-Q349 HydrophobicContact CZ3-CG 3.9Å; W345-Q349 WeakPolarHBondContact O-CG 3.47Å; W345-Q349 PolarHBondContact O-N 2.75Å; W345-Q349 VanDerWaalsContact O-N 3.11Å; A346-Q349 PolarHBondContact O-N 3.5Å; A347-Q349 PolarHBondContact O-N 3.35Å; Q349-K352 WeakPolarHBondContact O-CG 3.28Å
350A96.5Very high96.4Very high5 Ų542.1 Ų42.14%0.04121%0.213CC..Hα-helixtrans-69.4-36.1-172.300000113.3M224 V252 R294 A346 A347 K352M224-A350 HydrophobicContact SD-CB 3.92Å; V252-A350 HydrophobicContact CG1-CB 4.43Å; V252-A350 HydrophobicContact CG2-CB 4.27Å; R294-A350 PolarHBondContact NH2-O 2.9Å; A346-A350 WeakPolarHBondContact O-CB 3.27Å; A346-A350 PolarHBondContact O-N 2.89Å; A347-A350 PolarHBondContact O-N 3.3Å; A350-K352 PolarHBondContact O-N 3.24Å
351A97.5Very high96.6Very high0 Ų042.1 Ų42.10%021%0.213CC..G310 helixtrans-77.7-4-175.300000113.7L75 M224 A347 D353 L354 C360L75-A351 HydrophobicContact CD1-CB 3.93Å; L75-A351 HydrophobicContact CD2-CB 4.12Å; M224-A351 HydrophobicContact SD-CB 4.47Å; A347-A351 WeakPolarHBondContact O-CB 3.47Å; A347-A351 PolarHBondContact O-N 3.26Å; A351-D353 PolarHBondContact O-N 2.66Å; A351-L354 HydrophobicContact CB-CD1 4.18Å; A351-L354 WeakPolarHBondContact O-CB 3.49Å; A351-L354 PolarHBondContact O-N 3.03Å; A351-C360 HydrophobicContact CB-CB 4.19Å
352K96.3Very high96.9Very high118 Ų11842.1 Ų42.151%0.51321%0.213SC..G310 helixtrans-58.7-28177-71.3174.8176.4171.40112.9L75 L348 Q349 A350 L354L75-K352 HydrophobicContact CD2-CB 4.41Å; L75-K352 HydrophobicContact CD2-CG 3.84Å; L348-K352 WeakPolarHBondContact O-CE 3.22Å; Q349-K352 WeakPolarHBondContact O-CG 3.28Å; A350-K352 PolarHBondContact O-N 3.24Å; K352-L354 VanDerWaalsContact C-N 3.29Å
353D92.2Very high97Very high114 Ų11442.3 Ų42.361%0.6121%0.214SC*.G310 helixtrans-79-11.6179.5-55.8-35000113R294 A351R294-D353 IonicContact CZ-OD2 2.76Å; R294-D353 IonicContact NH1-OD2 2.69Å; R294-D353 PolarHBondContact NH1-OD2 2.72Å; R294-D353 IonicContact NH2-OD2 2.73Å; A351-D353 PolarHBondContact O-N 2.66Å
354L97.7Very high97Very high11 Ų1142.2 Ų42.26%0.05821%0.214CC..PPolyproline II helixtrans-84.2147-178.4-60.9179.9000112C77 D223 M224 A351 K352 Q358 C360C77-L354 HydrophobicContact CB-CB 3.59Å; C77-L354 HydrophobicContact CB-CD1 4.13Å; D223-L354 HydrophobicContact CB-CD2 4.24Å; M224-L354 HydrophobicContact CB-CD1 3.84Å; M224-L354 HydrophobicContact CE-CD1 4.03Å; M224-L354 HydrophobicContact CE-CD2 4.03Å; M224-L354 HydrophobicContact CE-CG 3.96Å; M224-L354 HydrophobicContact SD-CD1 4.27Å; A351-L354 HydrophobicContact CB-CD1 4.18Å; A351-L354 WeakPolarHBondContact O-CB 3.49Å; A351-L354 PolarHBondContact O-N 3.03Å; K352-L354 VanDerWaalsContact C-N 3.29Å; L354-Q358 HydrophobicContact CB-CB 4.31Å; L354-C360 HydrophobicContact CD1-CB 3.83Å
355K97.5Very high97Very high152 Ų15242.8 Ų42.866%0.66122%0.217SC*.PPolyproline II helixtrans-97.8168.9-177.7-58.5178.9-176.1178.90111.4C77 Q358C77-K355 WeakPolarHBondContact CA-O 3.41Å; K355-Q358 WeakPolarHBondContact O-CB 3.49Å; K355-Q358 PolarHBondContact O-N 3.42Å
356E97.2Very high97Very high170 Ų17039.9 Ų39.979%0.79421%0.206SC*.THydrogen-bonded Turntrans-56.2140170-172.1172.7-174.200110.8K76 Q358K76-E356 WeakPolarHBondContact O-CA 3.5Å; E356-Q358 VanDerWaalsContact C-N 3.28Å; E356-Q358 PolarHBondContact O-N 3.36Å
357G96.5Very high96.8Very high68 Ų6840.8 Ų40.870%0.70121%0.213SC*.THydrogen-bonded Turntrans85.1-14.2-175.200000115.2
358Q98.4Very high96.4Very high51 Ų5142 Ų4224%0.23822%0.22CC..  trans-84.3155.2173.7-61.8-169-83.500111.6C77 E78 D223 L354 K355 E356C77-Q358 WeakPolarHBondContact CA-O 3.34Å; C77-Q358 HydrophobicContact CB-CB 4.35Å; C77-Q358 VanDerWaalsContact CB-O 3.27Å; C77-Q358 WeakPolarHBondContact CB-O 3.49Å; E78-Q358 PolarHBondContact N-O 2.88Å; D223-Q358 HydrophobicContact CB-CB 3.99Å; D223-Q358 HydrophobicContact CB-CG 4.44Å; D223-Q358 PolarHBondContact OD1-NE2 2.73Å; D223-Q358 WeakPolarHBondContact OD2-CA 3.13Å; D223-Q358 WeakPolarHBondContact OD2-CB 3.41Å; L354-Q358 HydrophobicContact CB-CB 4.31Å; K355-Q358 WeakPolarHBondContact O-CB 3.49Å; K355-Q358 PolarHBondContact O-N 3.42Å; E356-Q358 VanDerWaalsContact C-N 3.28Å; E356-Q358 PolarHBondContact O-N 3.36Å
359K98.6Very high96.2Very high37 Ų3744.8 Ų44.816%0.16123%0.229CC..EExtended strand (participates in β ladder)trans-120.3131.8-179.7-54.5-172.1-162.4134.30113.1E78 L80 C218 S221 D223 M224E78-K359 HydrophobicContact CB-CG 4.25Å; E78-K359 WeakPolarHBondContact O-CA 3.48Å; E78-K359 WeakPolarHBondContact OE2-CD 2.94Å; E78-K359 WeakPolarHBondContact OE2-CE 3Å; L80-K359 HydrophobicContact CD1-CD 4.15Å; C218-K359 PolarHBondContact O-NZ 3.26Å; S221-K359 WeakPolarHBondContact O-CD 3.32Å; S221-K359 PolarHBondContact O-NZ 2.75Å; S221-K359 VanDerWaalsContact O-NZ 3.11Å; D223-K359 PolarHBondContact N-O 3.06Å; D223-K359 PolarHBondContact OD2-N 3.24Å; M224-K359 PolarHBondContact N-O 3.19Å
360C98.7Very high95.9Very high0 Ų041.3 Ų41.30%021%0.213CC..EExtended strand (participates in β ladder)trans-110.9124.7169.7-177.60000109.8E78 L79 L80 M224 A351 L354E78-C360 PolarHBondContact O-N 2.91Å; L79-C360 HydrophobicContact CD1-CB 3.78Å; L80-C360 PolarHBondContact N-O 3.06Å; M224-C360 HydrophobicContact CB-CB 4.24Å; M224-C360 CarbonylContact O-C 3.58Å; M224-C360 WeakPolarHBondContact O-CA 3.47Å; A351-C360 HydrophobicContact CB-CB 4.19Å; L354-C360 HydrophobicContact CD1-CB 3.83Å
361V98.7Very high95.5Very high1 Ų141.3 Ų41.31%0.00621%0.212CC..EExtended strand (participates in β ladder)trans-108.8128.81771790000109.8L63 L80 K82 I214 I222 M224 L225 V226L63-V361 HydrophobicContact CD1-CG1 3.91Å; L80-V361 HydrophobicContact CB-CG2 4.23Å; L80-V361 HydrophobicContact CD1-CG2 4.29Å; L80-V361 CarbonylContact O-C 3.59Å; L80-V361 WeakPolarHBondContact O-CA 3.02Å; K82-V361 HydrophobicContact CB-CG1 4.39Å; I214-V361 HydrophobicContact CD1-CG1 4.31Å; I214-V361 HydrophobicContact CG1-CG1 4.42Å; I214-V361 HydrophobicContact CG2-CG1 4.19Å; I214-V361 HydrophobicContact CG2-CG2 4.22Å; I222-V361 HydrophobicContact CG2-CG2 3.9Å; M224-V361 PolarHBondContact O-N 2.76Å; L225-V361 CarbonylContact C-O 3.45Å; L225-V361 WeakPolarHBondContact CA-O 3.19Å; L225-V361 HydrophobicContact CD1-CB 4.4Å; L225-V361 HydrophobicContact CD1-CG1 4.33Å; V226-V361 PolarHBondContact N-O 3.25Å
362V98.5Very high94.9Very high0 Ų046.2 Ų46.20%024%0.236CC..EExtended strand (participates in β ladder)trans-116130.7-179.8-169.90000110.1L79 L80 V81 K82 V226 N343 M344 A347 L364L79-V362 HydrophobicContact CD1-CG2 3.73Å; L80-V362 PolarHBondContact O-N 3.39Å; V81-V362 CarbonylContact C-O 3.49Å; V81-V362 VanDerWaalsContact CA-O 3.27Å; V81-V362 WeakPolarHBondContact CA-O 3.24Å; V81-V362 HydrophobicContact CG1-CB 4.12Å; K82-V362 PolarHBondContact N-O 3.04Å; V226-V362 HydrophobicContact CB-CG1 4.38Å; V226-V362 HydrophobicContact CB-CG2 4.4Å; V226-V362 WeakPolarHBondContact O-CA 3.42Å; N343-V362 HydrophobicContact CB-CG1 3.77Å; M344-V362 HydrophobicContact SD-CG2 4.47Å; A347-V362 HydrophobicContact CB-CB 4.41Å; A347-V362 HydrophobicContact CB-CG1 4.23Å; A347-V362 HydrophobicContact CB-CG2 3.3Å; V362-L364 HydrophobicContact CG1-CD2 4.35Å
363L98.2Very high94.4Very high4 Ų444.8 Ų44.82%0.02124%0.238CC..EExtended strand (participates in β ladder)trans-82.6125.3176.6-165.572000110.7K82 E84 V92 T210 V226 A227 I238 N343 P365K82-L363 HydrophobicContact CB-CD1 4.04Å; K82-L363 HydrophobicContact CG-CD1 3.93Å; E84-L363 HydrophobicContact CG-CD1 3.61Å; E84-L363 HydrophobicContact CG-CG 4.29Å; V92-L363 HydrophobicContact CG2-CD2 4.4Å; T210-L363 HydrophobicContact CG2-CD1 4.33Å; V226-L363 PolarHBondContact O-N 2.98Å; A227-L363 HydrophobicContact CB-CB 4.02Å; A227-L363 HydrophobicContact CB-CD2 4.16Å; I238-L363 HydrophobicContact CD1-CD1 4.25Å; I238-L363 HydrophobicContact CD1-CD2 4.21Å; N343-L363 PolarHBondContact ND2-O 2.75Å; L363-P365 WeakPolarHBondContact O-CD 3.1Å
364L97.2Very high93.9Very high0 Ų039.9 Ų39.90%021%0.211CC..EExtended strand (participates in β ladder)trans-106101.6175-58.4-172.6000110.1V81 K82 E84 Y85 L310 I316 V362V81-L364 HydrophobicContact CB-CD1 3.64Å; V81-L364 HydrophobicContact CB-CG 3.86Å; V81-L364 HydrophobicContact CG1-CD1 3.83Å; V81-L364 HydrophobicContact CG1-CD2 4.15Å; V81-L364 HydrophobicContact CG1-CG 4Å; V81-L364 HydrophobicContact CG2-CD1 3.94Å; K82-L364 PolarHBondContact O-N 3.31Å; E84-L364 WeakPolarHBondContact CB-O 3.32Å; E84-L364 PolarHBondContact N-O 3.45Å; Y85-L364 HydrophobicContact CD1-CB 4.11Å; Y85-L364 HydrophobicContact CE1-CB 4.03Å; Y85-L364 HydrophobicContact CE1-CD1 4.02Å; L310-L364 HydrophobicContact CD1-CD2 4.3Å; I316-L364 HydrophobicContact CG2-CD1 3.64Å; V362-L364 HydrophobicContact CG1-CD2 4.35Å
365P96Very high93.3Very high12 Ų1239.5 Ų39.58%0.07821%0.209CC..  trans-69.6-37.6-161.1-26.738.9000116.6S91 V92 S339 S340 L363S91-P365 CarbonylContact C-O 3.55Å; S91-P365 VanDerWaalsContact CA-O 3.29Å; S91-P365 WeakPolarHBondContact CA-O 3.38Å; V92-P365 HydrophobicContact CG1-CB 3.85Å; V92-P365 PolarHBondContact N-O 2.91Å; S339-P365 WeakPolarHBondContact OG-CG 3.18Å; S340-P365 VanDerWaalsContact OG-CD 3.24Å; S340-P365 WeakPolarHBondContact OG-CD 3.46Å; L363-P365 WeakPolarHBondContact O-CD 3.1Å
366D94.4Very high92.7Very high3 Ų333.5 Ų33.52%0.01618%0.184CC..BIsolated β-bridgetrans-156.2171-170.772.2-24000114.7N123 N370 Y371N123-D366 PolarHBondContact ND2-OD2 3.32Å; D366-N370 PolarHBondContact OD2-ND2 3.12Å; D366-Y371 PolarHBondContact OD1-OH 3.37Å; D366-Y371 WeakPolarHBondContact OD2-CE2 3.25Å; D366-Y371 VanDerWaalsContact OD2-CZ 3.24Å; D366-Y371 PolarHBondContact OD2-OH 3Å
367S93.1Very high92Very high19 Ų1927.2 Ų27.213%0.13316%0.158CC..  trans-88166.4-17171.60000113.6G90 R369 Y371G90-S367 PolarHBondContact O-N 2.97Å; S367-R369 PolarHBondContact O-N 2.97Å; S367-R369 WeakPolarHBondContact OG-CB 3.49Å; S367-R369 PolarHBondContact OG-N 3.4Å; S367-Y371 WeakPolarHBondContact O-CD2 3.48Å; S367-Y371 WeakPolarHBondContact O-CE2 3.19Å
368V90.5Very high91.1Very high25 Ų2529.1 Ų29.115%0.15215%0.149CC..G310 helixtrans-57.7-26.1173.2-38.70000113.9L317 G319 N370 Y371 M372 L376L317-V368 HydrophobicContact CB-CG1 3.69Å; L317-V368 HydrophobicContact CD2-CG1 4.22Å; L317-V368 WeakPolarHBondContact O-CG1 3.3Å; L317-V368 PolarHBondContact O-N 3Å; G319-V368 VanDerWaalsContact N-CG1 3.34Å; G319-V368 WeakPolarHBondContact O-CG1 3.49Å; V368-N370 PolarHBondContact O-N 3.24Å; V368-Y371 PolarHBondContact O-N 2.84Å; V368-M372 HydrophobicContact CG2-SD 3.97Å; V368-L376 HydrophobicContact CB-CD1 3.99Å; V368-L376 HydrophobicContact CB-CD2 4.12Å
369R92Very high90.1Very high78 Ų7829.2 Ų29.229%0.29415%0.149SC..G310 helixtrans-52.4-38.5-168.7-179.9-167.365-158.4-7.5111.9G89 E150 S367 Y371G89-R369 PolarHBondContact O-NH1 3.28Å; G89-R369 PolarHBondContact O-NH2 3.12Å; E150-R369 WeakPolarHBondContact CB-O 3.4Å; E150-R369 WeakPolarHBondContact CG-O 3.25Å; S367-R369 PolarHBondContact O-N 2.97Å; S367-R369 WeakPolarHBondContact OG-CB 3.49Å; S367-R369 PolarHBondContact OG-N 3.4Å; R369-Y371 PolarHBondContact O-N 2.92Å; R369-Y371 VanDerWaalsContact O-N 3.14Å
370N88.7Confident89.4Confident0 Ų028.4 Ų28.40%015%0.145CC..G310 helixtrans-70.5-8-175.9-65.9-18.9000113.3N123 S148 K151 D366 V368N123-N370 PolarHBondContact OD1-ND2 2.86Å; S148-N370 WeakPolarHBondContact CB-O 3.37Å; S148-N370 PolarHBondContact OG-O 3.16Å; K151-N370 HydrophobicContact CG-CB 4.27Å; D366-N370 PolarHBondContact OD2-ND2 3.12Å; V368-N370 PolarHBondContact O-N 3.24Å
371Y86.5Confident88.5Confident4 Ų428.4 Ų28.42%0.01615%0.145CC..G310 helixtrans-137.114.1-159.2-46.5-56.7000113.8E276 G337 D366 S367 V368 R369 T373 K374 F375 L376E276-Y371 HydrophobicContact CB-CE1 4.3Å; G337-Y371 VanDerWaalsContact CA-CE2 3.47Å; G337-Y371 VanDerWaalsContact CA-CG 3.46Å; D366-Y371 PolarHBondContact OD1-OH 3.37Å; D366-Y371 WeakPolarHBondContact OD2-CE2 3.25Å; D366-Y371 VanDerWaalsContact OD2-CZ 3.24Å; D366-Y371 PolarHBondContact OD2-OH 3Å; S367-Y371 WeakPolarHBondContact O-CD2 3.48Å; S367-Y371 WeakPolarHBondContact O-CE2 3.19Å; V368-Y371 PolarHBondContact O-N 2.84Å; R369-Y371 PolarHBondContact O-N 2.92Å; R369-Y371 VanDerWaalsContact O-N 3.14Å; Y371-T373 PolarHBondContact O-N 2.84Å; Y371-K374 PolarHBondContact O-N 2.74Å; Y371-F375 AromaticContact CD2-CE1 3.71Å; Y371-F375 HydrophobicContact CD2-CE1 3.71Å; Y371-F375 HydrophobicContact CG-CD1 4.19Å; Y371-F375 AromaticContact CG-CE1 3.67Å; Y371-F375 HydrophobicContact CG-CE1 3.67Å; Y371-L376 WeakPolarHBondContact O-CD1 3.34Å
372M86.6Confident87.5Confident103 Ų10329.3 Ų29.351%0.50715%0.153SC..THydrogen-bonded Turntrans-53.1-39.4-173.4-66.9-63.8-64.600113E150 V368 L376E150-M372 HydrophobicContact CG-CB 4.35Å; E150-M372 PolarHBondContact OE1-N 2.87Å; V368-M372 HydrophobicContact CG2-SD 3.97Å; M372-L376 WeakPolarHBondContact O-CB 3.38Å; M372-L376 HydrophobicContact SD-CD2 4.15Å
373T85.4Confident86.5Confident89 Ų8934.1 Ų34.155%0.54618%0.178SC..THydrogen-bonded Turntrans-93.86.7-179.1590000114E150 Y371E150-T373 WeakPolarHBondContact OE1-CB 3.32Å; E150-T373 WeakPolarHBondContact OE1-CG2 3.41Å; E150-T373 PolarHBondContact OE1-N 2.91Å; E150-T373 PolarHBondContact OE1-OG1 3.23Å; Y371-T373 PolarHBondContact O-N 2.84Å
374K82.4Confident85.4Confident11 Ų1134.9 Ų34.95%0.04818%0.181CC..THydrogen-bonded Turntrans-114.9-121.7-170.5-67.5160160.6-132.30110.8S148 E276 T335 Y371 L376 S377 W380S148-K374 VanDerWaalsContact CA-NZ 3.34Å; E276-K374 IonicContact OE1-NZ 3.37Å; E276-K374 PolarHBondContact OE1-NZ 3.19Å; T335-K374 VanDerWaalsContact C-NZ 3.32Å; T335-K374 WeakPolarHBondContact O-CD 3.32Å; T335-K374 WeakPolarHBondContact O-CE 3.33Å; T335-K374 WeakPolarHBondContact O-CG 3.28Å; T335-K374 PolarHBondContact O-NZ 2.89Å; T335-K374 PolarHBondContact OG1-NZ 3.42Å; Y371-K374 PolarHBondContact O-N 2.74Å; K374-L376 PolarHBondContact O-N 3.21Å; K374-S377 WeakPolarHBondContact O-CA 3.33Å; K374-S377 VanDerWaalsContact O-CB 3.25Å; K374-S377 WeakPolarHBondContact O-CB 3.07Å; K374-S377 PolarHBondContact O-N 3.45Å; K374-W380 VanDerWaalsContact C-CD2 3.42Å; K374-W380 HydrophobicContact CB-CD2 4.29Å; K374-W380 VanDerWaalsContact O-CB 3.32Å; K374-W380 WeakPolarHBondContact O-CB 3.32Å
375F84.6Confident84.4Confident2 Ų236.4 Ų36.41%0.00920%0.197CC..THydrogen-bonded Turntrans-60.8-15.8-179.583.1-77.6000114.6L304 A307 L308 G337 Y371 S377 W380 M381L304-F375 HydrophobicContact CB-CB 4.49Å; L304-F375 HydrophobicContact CD1-CB 4.46Å; L304-F375 HydrophobicContact CD2-CB 3.85Å; L304-F375 HydrophobicContact CD2-CD1 4.36Å; L304-F375 HydrophobicContact CD2-CD2 4.26Å; L304-F375 HydrophobicContact CD2-CG 3.93Å; L304-F375 HydrophobicContact CG-CB 4.49Å; A307-F375 HydrophobicContact CB-CD2 4.49Å; A307-F375 HydrophobicContact CB-CE2 3.69Å; A307-F375 HydrophobicContact CB-CZ 4.2Å; L308-F375 HydrophobicContact CD2-CD2 3.69Å; L308-F375 HydrophobicContact CD2-CE2 4.05Å; L308-F375 HydrophobicContact CG-CD2 3.97Å; L308-F375 HydrophobicContact CG-CE2 4.38Å; G337-F375 WeakPolarHBondContact O-CD1 3.45Å; G337-F375 WeakPolarHBondContact O-CE1 3.41Å; G337-F375 WeakPolarHBondContact O-CZ 3.29Å; Y371-F375 AromaticContact CD2-CE1 3.71Å; Y371-F375 HydrophobicContact CD2-CE1 3.71Å; Y371-F375 HydrophobicContact CG-CD1 4.19Å; Y371-F375 AromaticContact CG-CE1 3.67Å; Y371-F375 HydrophobicContact CG-CE1 3.67Å; F375-S377 VanDerWaalsContact C-N 3.34Å; F375-W380 HydrophobicContact CB-CE3 4.25Å; F375-W380 HydrophobicContact CB-CZ3 3.97Å; F375-M381 HydrophobicContact CB-CG 4.48Å; F375-M381 HydrophobicContact CB-SD 3.65Å; F375-M381 WeakPolarHBondContact O-CG 3.34Å
376L83.6Confident83.3Confident26 Ų2637.8 Ų37.814%0.13620%0.2CC..THydrogen-bonded Turntrans-68.7-30167.1-83110.2000113.4L320 V368 Y371 M372 K374L320-L376 HydrophobicContact CB-CD2 3.74Å; L320-L376 HydrophobicContact CB-CG 4.46Å; L320-L376 HydrophobicContact CD2-CD2 3.76Å; L320-L376 HydrophobicContact CG-CD2 4.35Å; L320-L376 WeakPolarHBondContact O-CA 3.32Å; V368-L376 HydrophobicContact CB-CD1 3.99Å; V368-L376 HydrophobicContact CB-CD2 4.12Å; Y371-L376 WeakPolarHBondContact O-CD1 3.34Å; M372-L376 WeakPolarHBondContact O-CB 3.38Å; M372-L376 HydrophobicContact SD-CD2 4.15Å; K374-L376 PolarHBondContact O-N 3.21Å
377S82.9Confident82.1Confident38 Ų3838.2 Ų38.227%0.26620%0.203SC..SBendtrans-79.7123.3175.9173.40000110.5K374 F375 K379 W380 M381K374-S377 WeakPolarHBondContact O-CA 3.33Å; K374-S377 VanDerWaalsContact O-CB 3.25Å; K374-S377 WeakPolarHBondContact O-CB 3.07Å; K374-S377 PolarHBondContact O-N 3.45Å; F375-S377 VanDerWaalsContact C-N 3.34Å; S377-K379 VanDerWaalsContact C-N 3.33Å; S377-W380 PolarHBondContact O-N 2.78Å; S377-W380 PolarHBondContact OG-N 3.13Å; S377-M381 WeakPolarHBondContact O-CG 3.39Å; S377-M381 PolarHBondContact O-N 3.31Å; S377-M381 VanDerWaalsContact O-N 3.09Å
378Q78Confident80.3Confident109 Ų10939.3 Ų39.351%0.50921%0.21SC..Hα-helixtrans-63.5-40.6175.7-70-176.542.100111.4W380 M381 A382Q378-W380 PolarHBondContact O-N 2.8Å; Q378-M381 PolarHBondContact O-N 3.48Å; Q378-A382 VanDerWaalsContact O-CB 3.3Å; Q378-A382 WeakPolarHBondContact O-CB 3.47Å; Q378-A382 PolarHBondContact O-N 3.19Å
379K77.2Confident78.4Confident52 Ų5242.5 Ų42.523%0.22622%0.224CC..Hα-helixtrans-55.9-51.6174.1171.3168.1169.756.80110.5S377 M381 A382 D383 E477S377-K379 VanDerWaalsContact C-N 3.33Å; K379-M381 VanDerWaalsContact C-N 3.27Å; K379-M381 PolarHBondContact O-N 2.84Å; K379-A382 CarbonylContact O-C 3.53Å; K379-A382 PolarHBondContact O-N 2.69Å; K379-D383 WeakPolarHBondContact CG-OD2 3.44Å; K379-D383 IonicContact NZ-OD1 2.73Å; K379-D383 IonicContact NZ-OD2 2.7Å; K379-D383 PolarHBondContact NZ-OD2 2.73Å; K379-D383 WeakPolarHBondContact O-CB 3.47Å; K379-D383 PolarHBondContact O-N 3.47Å; K379-E477 IonicContact NZ-OE1 2.79Å; K379-E477 PolarHBondContact NZ-OE1 3.4Å
380W83.3Confident76.3Confident20 Ų2045.2 Ų45.28%0.07624%0.24CC..Hα-helixtrans-59.5-38.5179.9-177.4101.3000112.7E274 L304 L334 S336 K374 F375 S377 Q378 R384 W386E274-W380 HydrophobicContact CB-CH2 4.09Å; E274-W380 HydrophobicContact CB-CZ2 4.45Å; E274-W380 HydrophobicContact CG-CH2 4.05Å; E274-W380 HydrophobicContact CG-CZ2 4.28Å; L304-W380 HydrophobicContact CD1-CH2 4.21Å; L304-W380 HydrophobicContact CD1-CZ3 4.15Å; L334-W380 WeakPolarHBondContact O-CZ2 3.19Å; L334-W380 PolarHBondContact O-NE1 2.84Å; S336-W380 VanDerWaalsContact CB-CZ2 3.47Å; S336-W380 WeakPolarHBondContact OG-CH2 3.44Å; K374-W380 VanDerWaalsContact C-CD2 3.42Å; K374-W380 HydrophobicContact CB-CD2 4.29Å; K374-W380 VanDerWaalsContact O-CB 3.32Å; K374-W380 WeakPolarHBondContact O-CB 3.32Å; F375-W380 HydrophobicContact CB-CE3 4.25Å; F375-W380 HydrophobicContact CB-CZ3 3.97Å; S377-W380 PolarHBondContact O-N 2.78Å; S377-W380 PolarHBondContact OG-N 3.13Å; Q378-W380 PolarHBondContact O-N 2.8Å; W380-R384 VanDerWaalsContact CD1-NH1 3.28Å; W380-R384 VanDerWaalsContact CZ3-CD 3.42Å; W380-R384 WeakPolarHBondContact O-CD 3.34Å; W380-R384 PolarHBondContact O-NH1 3.4Å; W380-W386 HydrophobicContact CH2-CE3 4.44Å; W380-W386 HydrophobicContact CH2-CH2 4.48Å; W380-W386 AromaticContact CH2-CZ3 3.64Å; W380-W386 HydrophobicContact CH2-CZ3 3.64Å; W380-W386 HydrophobicContact CZ3-CE3 4.01Å; W380-W386 AromaticContact CZ3-CZ3 3.65Å; W380-W386 HydrophobicContact CZ3-CZ3 3.65Å
381M81.1Confident74.1Confident0 Ų047.4 Ų47.40%025%0.254CS..Hα-helixtrans-70.6-34.3175.6-71.5-69.7-63.100112.6L304 L305 L308 F375 S377 Q378 K379 W386 L387L304-M381 HydrophobicContact CB-CE 4.29Å; L304-M381 HydrophobicContact CB-SD 4.43Å; L305-M381 HydrophobicContact CD2-CE 4.29Å; L308-M381 HydrophobicContact CD1-CE 3.59Å; L308-M381 HydrophobicContact CD1-SD 4.29Å; F375-M381 HydrophobicContact CB-CG 4.48Å; F375-M381 HydrophobicContact CB-SD 3.65Å; F375-M381 WeakPolarHBondContact O-CG 3.34Å; S377-M381 WeakPolarHBondContact O-CG 3.39Å; S377-M381 PolarHBondContact O-N 3.31Å; S377-M381 VanDerWaalsContact O-N 3.09Å; Q378-M381 PolarHBondContact O-N 3.48Å; K379-M381 VanDerWaalsContact C-N 3.27Å; K379-M381 PolarHBondContact O-N 2.84Å; M381-W386 HydrophobicContact CE-CB 3.77Å; M381-W386 HydrophobicContact CE-CE3 4.13Å; M381-W386 PolarHBondContact O-N 2.85Å; M381-W386 HydrophobicContact SD-CE3 4.06Å; M381-L387 HydrophobicContact CB-CB 4.16Å; M381-L387 HydrophobicContact CB-CD1 3.6Å; M381-L387 HydrophobicContact CB-CG 3.86Å; M381-L387 HydrophobicContact CE-CD1 4.35Å; M381-L387 HydrophobicContact CE-CG 4.18Å; M381-L387 HydrophobicContact CG-CD1 4Å; M381-L387 PolarHBondContact O-N 3.01Å
382A77.3Confident72.3Confident21 Ų2151.4 Ų51.417%0.17428%0.278CS..Hα-helixtrans-75.3-40.1178.600000112.3Q378 K379 R384 G385 L387 E389Q378-A382 VanDerWaalsContact O-CB 3.3Å; Q378-A382 WeakPolarHBondContact O-CB 3.47Å; Q378-A382 PolarHBondContact O-N 3.19Å; K379-A382 CarbonylContact O-C 3.53Å; K379-A382 PolarHBondContact O-N 2.69Å; A382-R384 PolarHBondContact O-N 3.05Å; A382-G385 PolarHBondContact O-N 3.46Å; A382-L387 VanDerWaalsContact CA-O 3.28Å; A382-L387 WeakPolarHBondContact CA-O 3.26Å; A382-E389 HydrophobicContact CB-CG 3.78Å
383D77.3Confident70.4Confident100 Ų10053.5 Ų53.554%0.53529%0.292SS..THydrogen-bonded Turntrans-57.7-20.6173.2-66.8-19000111.8K379K379-D383 WeakPolarHBondContact CG-OD2 3.44Å; K379-D383 IonicContact NZ-OD1 2.73Å; K379-D383 IonicContact NZ-OD2 2.7Å; K379-D383 PolarHBondContact NZ-OD2 2.73Å; K379-D383 WeakPolarHBondContact O-CB 3.47Å; K379-D383 PolarHBondContact O-N 3.47Å
384R76.2Confident68.4Low21 Ų2152.3 Ų52.38%0.07930%0.297CS..THydrogen-bonded Turntrans-100.14.8175.4-74.1161.4-179.767.311.8114.7E274 T333 L334 W380 A382 W386E274-R384 IonicContact OE1-CZ 3.35Å; E274-R384 IonicContact OE1-NE 2.56Å; E274-R384 PolarHBondContact OE1-NE 2.89Å; E274-R384 IonicContact OE1-NH2 3.54Å; E274-R384 PolarHBondContact OE1-NH2 3.33Å; T333-R384 VanDerWaalsContact C-NH2 3.3Å; T333-R384 PolarHBondContact O-NH2 2.93Å; L334-R384 VanDerWaalsContact CA-NH2 3.33Å; L334-R384 PolarHBondContact O-NH2 3.36Å; L334-R384 VanDerWaalsContact O-NH2 3.11Å; W380-R384 VanDerWaalsContact CD1-NH1 3.28Å; W380-R384 VanDerWaalsContact CZ3-CD 3.42Å; W380-R384 WeakPolarHBondContact O-CD 3.34Å; W380-R384 PolarHBondContact O-NH1 3.4Å; A382-R384 PolarHBondContact O-N 3.05Å; R384-W386 HydrophobicContact CB-CD2 3.86Å; R384-W386 HydrophobicContact CB-CE3 3.89Å; R384-W386 HydrophobicContact CB-CG 4.28Å; R384-W386 HydrophobicContact CB-CZ3 4.22Å; R384-W386 HydrophobicContact CG-CZ3 4.45Å; R384-W386 VanDerWaalsContact O-CD1 3.24Å; R384-W386 PolarHBondContact O-N 2.87Å; R384-W386 PolarHBondContact O-NE1 3.42Å
385G74.8Confident66.8Low32 Ų3252.9 Ų52.933%0.3330%0.303SS..THydrogen-bonded Turntrans66.915.7-177.900000114.6A382A382-G385 PolarHBondContact O-N 3.46Å
386W74.1Confident65.2Low40 Ų4059 Ų5915%0.15234%0.343CS..SBendtrans-92.1-21.5-177.9-64-17.3000113.7E274 D300 R301 L304 W380 M381 R384E274-W386 HydrophobicContact CB-CH2 3.92Å; E274-W386 HydrophobicContact CB-CZ3 4.36Å; E274-W386 HydrophobicContact CG-CH2 3.51Å; E274-W386 HydrophobicContact CG-CZ2 4.49Å; E274-W386 HydrophobicContact CG-CZ3 4.1Å; D300-W386 HydrophobicContact CB-CH2 3.35Å; D300-W386 HydrophobicContact CB-CZ2 3.56Å; D300-W386 HydrophobicContact CB-CZ3 4.25Å; R301-W386 HydrophobicContact CB-CD2 4.39Å; R301-W386 HydrophobicContact CB-CG 4.22Å; R301-W386 HydrophobicContact CG-CB 4.43Å; R301-W386 HydrophobicContact CG-CG 4.01Å; L304-W386 HydrophobicContact CD1-CE3 3.62Å; L304-W386 HydrophobicContact CD1-CH2 3.78Å; L304-W386 HydrophobicContact CD1-CZ3 3.05Å; L304-W386 HydrophobicContact CG-CZ3 4.48Å; W380-W386 HydrophobicContact CH2-CE3 4.44Å; W380-W386 HydrophobicContact CH2-CH2 4.48Å; W380-W386 AromaticContact CH2-CZ3 3.64Å; W380-W386 HydrophobicContact CH2-CZ3 3.64Å; W380-W386 HydrophobicContact CZ3-CE3 4.01Å; W380-W386 AromaticContact CZ3-CZ3 3.65Å; W380-W386 HydrophobicContact CZ3-CZ3 3.65Å; M381-W386 HydrophobicContact CE-CB 3.77Å; M381-W386 HydrophobicContact CE-CE3 4.13Å; M381-W386 PolarHBondContact O-N 2.85Å; M381-W386 HydrophobicContact SD-CE3 4.06Å; R384-W386 HydrophobicContact CB-CD2 3.86Å; R384-W386 HydrophobicContact CB-CE3 3.89Å; R384-W386 HydrophobicContact CB-CG 4.28Å; R384-W386 HydrophobicContact CB-CZ3 4.22Å; R384-W386 HydrophobicContact CG-CZ3 4.45Å; R384-W386 VanDerWaalsContact O-CD1 3.24Å; R384-W386 PolarHBondContact O-N 2.87Å; R384-W386 PolarHBondContact O-NE1 3.42Å
387L67.8Low64.2Low13 Ų1363.4 Ų63.47%0.06837%0.366CS..SBendtrans-126.2140.3166.1-66.4177.3000109L305 Y321 A324 M381 A382L305-L387 HydrophobicContact CD2-CD2 3.96Å; Y321-L387 HydrophobicContact CE2-CD1 4.03Å; Y321-L387 HydrophobicContact CE2-CD2 3.9Å; A324-L387 VanDerWaalsContact O-CD2 3.29Å; A324-L387 WeakPolarHBondContact O-CD2 3.19Å; M381-L387 HydrophobicContact CB-CB 4.16Å; M381-L387 HydrophobicContact CB-CD1 3.6Å; M381-L387 HydrophobicContact CB-CG 3.86Å; M381-L387 HydrophobicContact CE-CD1 4.35Å; M381-L387 HydrophobicContact CE-CG 4.18Å; M381-L387 HydrophobicContact CG-CD1 4Å; M381-L387 PolarHBondContact O-N 3.01Å; A382-L387 VanDerWaalsContact CA-O 3.28Å; A382-L387 WeakPolarHBondContact CA-O 3.26Å
388S56.7Low63.6Low42 Ų4263.4 Ų63.429%0.29437%0.373SS..  trans-82.7131.1165.944.10000108.7Q325 Q390Q325-S388 PolarHBondContact O-OG 3.23Å; Q325-S388 VanDerWaalsContact O-OG 3.09Å; S388-Q390 VanDerWaalsContact C-N 3.34Å; S388-Q390 PolarHBondContact O-N 2.93Å
389E50.9Low63.7Low92 Ų9261.6 Ų61.643%0.4336%0.361SS..  trans-6598.7164.2-74.7-171.9167.800108A382A382-E389 HydrophobicContact CB-CG 3.78Å
390Q46.3Very low63.6Low135 Ų13560 Ų6063%0.63136%0.355SS*.  trans-81.3128.2166.2-73.7-89.1-39.800107.3A324 S388 T392A324-Q390 HydrophobicContact CB-CG 3.96Å; S388-Q390 VanDerWaalsContact C-N 3.34Å; S388-Q390 PolarHBondContact O-N 2.93Å; Q390-T392 PolarHBondContact O-N 2.97Å
391P44.1Very low63.4Low46 Ų4665.6 Ų65.630%0.29938%0.382SS..  trans-46.6118.9167-30.737.6000110.1N393 V486P391-N393 PolarHBondContact O-N 3.43Å; P391-V486 HydrophobicContact CB-CG2 3.89Å; P391-V486 HydrophobicContact CG-CG1 4.18Å; P391-V486 HydrophobicContact CG-CG2 4.08Å
392T47.8Very low63.6Low87 Ų8771.1 Ų71.153%0.53441%0.406SS..SBendtrans-66101.8173.948.40000108.4Q390 E490Q390-T392 PolarHBondContact O-N 2.97Å; T392-E490 PolarHBondContact OG1-OE1 3.35Å
393N47.7Very low64Low147 Ų14774.2 Ų74.279%0.78641%0.413SS*.SBendtrans57.6117.5-177.4-65.4-30.2000114.7P391 S395 Q400P391-N393 PolarHBondContact O-N 3.43Å; N393-S395 PolarHBondContact O-N 3.26Å; N393-Q400 PolarHBondContact O-NE2 3.05Å
394G43Very low64.4Low64 Ų6469.6 Ų69.666%0.6639%0.388SS*.  trans-48.4109.6166.500000110.1Q400G394-Q400 VanDerWaalsContact CA-OE1 3.23Å
395S47.6Very low64.8Low24 Ų2472 Ų7217%0.16840%0.403CS..  trans-63.3138.3170.9740000106.6N393 D397 G398 W399 Q400N393-S395 PolarHBondContact O-N 3.26Å; S395-D397 PolarHBondContact O-N 2.72Å; S395-G398 PolarHBondContact O-N 3.05Å; S395-W399 VanDerWaalsContact CB-NE1 3.29Å; S395-W399 PolarHBondContact OG-NE1 2.94Å; S395-Q400 VanDerWaalsContact N-CD 3.29Å
396P51.6Low65.3Low131 Ų13174.4 Ų74.485%0.85141%0.411SS*.THydrogen-bonded Turntrans-53.9-22179.8-21.931.1000113.7
397D61.8Low65.7Low117 Ų11774.7 Ų74.763%0.62642%0.415SS*.THydrogen-bonded Turntrans-94.81.4-164.8-22.3-34.2000113.3S395 W399S395-D397 PolarHBondContact O-N 2.72Å; D397-W399 PolarHBondContact O-N 3.34Å
398G70.7Confident66.3Low39 Ų3980.3 Ų80.340%0.40246%0.455SS..  trans63.76.3176.200000115.4S395 Q400 Q401S395-G398 PolarHBondContact O-N 3.05Å; G398-Q400 PolarHBondContact O-N 2.82Å; G398-Q401 PolarHBondContact O-N 3.23Å
399W80Confident67.1Low70 Ų7079.6 Ų79.627%0.26545%0.449SS..G310 helixtrans-62.5-29.9-176.567.5-101.8000112.4S395 D397 Q401 K402 I485 H489S395-W399 VanDerWaalsContact CB-NE1 3.29Å; S395-W399 PolarHBondContact OG-NE1 2.94Å; D397-W399 PolarHBondContact O-N 3.34Å; W399-Q401 PolarHBondContact O-N 3.34Å; W399-Q401 VanDerWaalsContact O-N 3.17Å; W399-K402 WeakPolarHBondContact O-CB 3.4Å; W399-K402 PolarHBondContact O-N 2.77Å; W399-I485 HydrophobicContact CE3-CB 4.16Å; W399-I485 HydrophobicContact CE3-CG2 3.61Å; W399-I485 HydrophobicContact CZ3-CB 4.42Å; W399-I485 HydrophobicContact CZ3-CG2 3.71Å; W399-H489 HydrophobicContact CH2-CB 3.82Å; W399-H489 AromaticContact CH2-CD2 3.86Å; W399-H489 AromaticContact CH2-CG 3.63Å; W399-H489 HydrophobicContact CZ3-CB 3.88Å
400Q75.5Confident68.3Low19 Ų1979.7 Ų79.79%0.08945%0.453CS..G310 helixtrans-54.5-35.1179.9-72.5167-2600113.6N393 G394 S395 G398 V486N393-Q400 PolarHBondContact O-NE2 3.05Å; G394-Q400 VanDerWaalsContact CA-OE1 3.23Å; S395-Q400 VanDerWaalsContact N-CD 3.29Å; G398-Q400 PolarHBondContact O-N 2.82Å; Q400-V486 HydrophobicContact CB-CB 3.76Å; Q400-V486 HydrophobicContact CB-CG1 4.4Å; Q400-V486 HydrophobicContact CB-CG2 4.23Å; Q400-V486 HydrophobicContact CG-CB 4.06Å; Q400-V486 HydrophobicContact CG-CG2 4.08Å; Q400-V486 WeakPolarHBondContact O-CB 3.33Å; Q400-V486 VanDerWaalsContact O-CG1 3.27Å; Q400-V486 WeakPolarHBondContact O-CG1 3.5Å; Q400-V486 PolarHBondContact O-N 3.36Å; Q400-V486 VanDerWaalsContact O-N 3.07Å
401Q78.8Confident69.9Low138 Ų13878 Ų7865%0.64545%0.454SS*.G310 helixtrans-94.1-7.9-178.5-63.9-65.6-16.400113.2G398 W399G398-Q401 PolarHBondContact O-N 3.23Å; W399-Q401 PolarHBondContact O-N 3.34Å; W399-Q401 VanDerWaalsContact O-N 3.17Å
402K85.1Confident71.9Confident116 Ų11676.8 Ų76.850%0.50445%0.446SS..SBendtrans-65.9151173.1-67.9-176.2-178.8178.30108.9W399 P484 I485W399-K402 WeakPolarHBondContact O-CB 3.4Å; W399-K402 PolarHBondContact O-N 2.77Å; K402-P484 CarbonylContact O-C 3.54Å; K402-P484 WeakPolarHBondContact O-CA 3.28Å; K402-I485 HydrophobicContact CB-CD1 3.73Å; K402-I485 HydrophobicContact CB-CG1 4.45Å; K402-I485 WeakPolarHBondContact O-CG1 3.4Å; K402-I485 PolarHBondContact O-N 3.14Å
403R86.3Confident73.9Confident85 Ų8573.2 Ų73.232%0.32142%0.424SS..BIsolated β-bridgetrans-84.8149.2178.9-67.5173.458.5-117.8-16.5109.8D405 T406 K482 C483R403-D405 WeakPolarHBondContact CB-OD1 3.22Å; R403-D405 VanDerWaalsContact CZ-CG 3.42Å; R403-D405 IonicContact CZ-OD1 3Å; R403-D405 VanDerWaalsContact CZ-OD1 3.28Å; R403-D405 IonicContact CZ-OD2 2.67Å; R403-D405 IonicContact NE-OD1 3.28Å; R403-D405 VanDerWaalsContact NH1-CG 3.33Å; R403-D405 IonicContact NH1-OD1 2.7Å; R403-D405 PolarHBondContact NH1-OD1 3.32Å; R403-D405 IonicContact NH1-OD2 3.47Å; R403-D405 PolarHBondContact NH1-OD2 2.93Å; R403-D405 IonicContact NH2-OD1 2.68Å; R403-D405 PolarHBondContact NH2-OD1 2.85Å; R403-D405 IonicContact NH2-OD2 3.45Å; R403-D405 PolarHBondContact NH2-OD2 3.24Å; R403-D405 PolarHBondContact O-N 3.28Å; R403-T406 HydrophobicContact CB-CG2 4.41Å; R403-T406 WeakPolarHBondContact O-CB 3.36Å; R403-T406 PolarHBondContact O-N 2.83Å; R403-T406 PolarHBondContact O-OG1 3.19Å; R403-K482 VanDerWaalsContact NE-CA 3.33Å; R403-C483 WeakPolarHBondContact CA-O 3.31Å
404V84.8Confident76Confident4 Ų469.1 Ų69.12%0.02440%0.399CS..G310 helixtrans-58.3-33.4179.8173.20000112.1T406 L407 C483 I485 V488 V500V404-T406 PolarHBondContact O-N 3.23Å; V404-L407 WeakPolarHBondContact O-CB 3.33Å; V404-L407 PolarHBondContact O-N 3.26Å; V404-C483 HydrophobicContact CG2-CB 4.22Å; V404-C483 VanDerWaalsContact CG2-O 3.24Å; V404-C483 WeakPolarHBondContact CG2-O 3.27Å; V404-C483 PolarHBondContact N-O 3.21Å; V404-I485 HydrophobicContact CG2-CG1 4.33Å; V404-V488 HydrophobicContact CG2-CB 4.3Å; V404-V488 HydrophobicContact CG2-CG2 3.34Å; V404-V500 HydrophobicContact CG1-CB 4.25Å; V404-V500 HydrophobicContact CG1-CG1 3.73Å; V404-V500 HydrophobicContact CG1-CG2 3.48Å; V404-V500 VanDerWaalsContact CG1-CG2 3.48Å
405D85.8Confident78.4Confident72 Ų7266.1 Ų66.139%0.38537%0.368SS..G310 helixtrans-63.4-9174.574.6-21.1000115.1R403 E481R403-D405 WeakPolarHBondContact CB-OD1 3.22Å; R403-D405 VanDerWaalsContact CZ-CG 3.42Å; R403-D405 IonicContact CZ-OD1 3Å; R403-D405 VanDerWaalsContact CZ-OD1 3.28Å; R403-D405 IonicContact CZ-OD2 2.67Å; R403-D405 IonicContact NE-OD1 3.28Å; R403-D405 VanDerWaalsContact NH1-CG 3.33Å; R403-D405 IonicContact NH1-OD1 2.7Å; R403-D405 PolarHBondContact NH1-OD1 3.32Å; R403-D405 IonicContact NH1-OD2 3.47Å; R403-D405 PolarHBondContact NH1-OD2 2.93Å; R403-D405 IonicContact NH2-OD1 2.68Å; R403-D405 PolarHBondContact NH2-OD1 2.85Å; R403-D405 IonicContact NH2-OD2 3.45Å; R403-D405 PolarHBondContact NH2-OD2 3.24Å; R403-D405 PolarHBondContact O-N 3.28Å; D405-E481 HydrophobicContact CB-CB 4.22Å; D405-E481 WeakPolarHBondContact CB-O 3.45Å; D405-E481 PolarHBondContact N-O 2.94Å
406T84.9Confident80.6Confident82 Ų8268.1 Ų68.150%0.50338%0.38SS..G310 helixtrans-84.9-11.5171.870.10000113.4R403 V404R403-T406 HydrophobicContact CB-CG2 4.41Å; R403-T406 WeakPolarHBondContact O-CB 3.36Å; R403-T406 PolarHBondContact O-N 2.83Å; R403-T406 PolarHBondContact O-OG1 3.19Å; V404-T406 PolarHBondContact O-N 3.23Å
407L83.4Confident82.5Confident46 Ų4664 Ų6424%0.24135%0.349CS..SBendtrans-79.4140.1175.1-64.5173000110.1V404 V409 I485 A513 F515V404-L407 WeakPolarHBondContact O-CB 3.33Å; V404-L407 PolarHBondContact O-N 3.26Å; L407-V409 HydrophobicContact CB-CG1 4.46Å; L407-V409 WeakPolarHBondContact O-CG2 3.44Å; L407-I485 HydrophobicContact CD1-CD1 4Å; L407-I485 HydrophobicContact CD1-CG1 4.09Å; L407-I485 HydrophobicContact CD1-CG2 4.5Å; L407-I485 HydrophobicContact CD2-CD1 3.83Å; L407-I485 HydrophobicContact CG-CD1 3.77Å; L407-I485 HydrophobicContact CG-CG1 4.34Å; L407-A513 HydrophobicContact CD1-CB 4.4Å; L407-F515 HydrophobicContact CD1-CE2 4.17Å; L407-F515 HydrophobicContact CD1-CZ 4.45Å; L407-F515 HydrophobicContact CD2-CZ 4.43Å
408S79.3Confident84Confident130 Ų13064.7 Ų64.791%0.90935%0.353SS*.  trans-84.4112.7166.9-700000108.8
409V73.1Confident85Confident27 Ų2763.1 Ų63.116%0.16434%0.335CS..  trans-132.6131.3-172.5-93.90000109.5L407 F511 V512 A513L407-V409 HydrophobicContact CB-CG1 4.46Å; L407-V409 WeakPolarHBondContact O-CG2 3.44Å; V409-F511 HydrophobicContact CB-CB 3.83Å; V409-F511 HydrophobicContact CB-CD1 3.99Å; V409-F511 HydrophobicContact CB-CG 4.31Å; V409-F511 HydrophobicContact CG2-CB 3.44Å; V409-F511 VanDerWaalsContact CG2-CB 3.44Å; V409-F511 HydrophobicContact CG2-CD1 3.46Å; V409-F511 VanDerWaalsContact CG2-CD1 3.46Å; V409-F511 HydrophobicContact CG2-CE1 4.37Å; V409-F511 HydrophobicContact CG2-CG 3.62Å; V409-V512 WeakPolarHBondContact CG1-O 3.28Å; V409-A513 VanDerWaalsContact CG1-CA 3.43Å; V409-A513 HydrophobicContact CG1-CB 3.56Å
410D75.8Confident85.5Confident94 Ų9462.7 Ų62.750%0.50334%0.341SS..PPolyproline II helixtrans-63.2144.8179.2-50-58.5000110.4K434D410-K434 VanDerWaalsContact CB-NZ 3.33Å; D410-K434 IonicContact OD2-NZ 3.47Å; D410-K434 PolarHBondContact OD2-NZ 2.86Å
411P80.6Confident86.1Confident100 Ų10063.7 Ų63.765%0.64934%0.344SS*.PPolyproline II helixtrans-59.4146.3175.623.4-32.2000110.9
412P85.4Confident86.5Confident21 Ų2160.5 Ų60.514%0.13634%0.337CS..PPolyproline II helixtrans-64.7155.2177.427.1-32000111.2F414 F437 T510P412-F414 HydrophobicContact CB-CE2 4Å; P412-F414 HydrophobicContact CB-CZ 3.95Å; P412-F414 HydrophobicContact CG-CD2 4.21Å; P412-F414 HydrophobicContact CG-CE1 4.47Å; P412-F414 HydrophobicContact CG-CE2 3.31Å; P412-F414 HydrophobicContact CG-CZ 3.43Å; P412-F414 VanDerWaalsContact CG-CZ 3.43Å; P412-F437 HydrophobicContact CB-CD2 3.68Å; P412-F437 HydrophobicContact CB-CE2 3.97Å; P412-T510 WeakPolarHBondContact CB-O 3.13Å; P412-T510 WeakPolarHBondContact CD-O 3.34Å; P412-T510 WeakPolarHBondContact CG-O 3.35Å
413V90.9Very high86.8Confident12 Ų1259.1 Ų59.17%0.07333%0.332CS..EExtended strand (participates in β ladder)trans-96.9125.3167179.90000108.6L427 K430 A431 I436 F437V413-L427 HydrophobicContact CG1-CB 4.02Å; V413-L427 HydrophobicContact CG1-CD2 3.59Å; V413-L427 HydrophobicContact CG1-CG 4.26Å; V413-K430 HydrophobicContact CG2-CB 4.26Å; V413-K430 HydrophobicContact CG2-CD 4.34Å; V413-K430 HydrophobicContact CG2-CG 3.97Å; V413-A431 HydrophobicContact CB-CB 4Å; V413-A431 HydrophobicContact CG2-CB 3.85Å; V413-I436 HydrophobicContact CG1-CG2 4.39Å; V413-I436 WeakPolarHBondContact O-CA 3.44Å; V413-F437 PolarHBondContact O-N 2.86Å
414F92.4Very high87Confident61 Ų6155.1 Ų55.127%0.26832%0.317SS..EExtended strand (participates in β ladder)trans-102.8146.8175.1-65.1-78.3000111.3P412 F437 L439 A508P412-F414 HydrophobicContact CB-CE2 4Å; P412-F414 HydrophobicContact CB-CZ 3.95Å; P412-F414 HydrophobicContact CG-CD2 4.21Å; P412-F414 HydrophobicContact CG-CE1 4.47Å; P412-F414 HydrophobicContact CG-CE2 3.31Å; P412-F414 HydrophobicContact CG-CZ 3.43Å; P412-F414 VanDerWaalsContact CG-CZ 3.43Å; F414-F437 CarbonylContact C-O 3.59Å; F414-F437 WeakPolarHBondContact CA-O 3.32Å; F414-F437 HydrophobicContact CD1-CB 3.56Å; F414-F437 HydrophobicContact CE1-CB 3.6Å; F414-F437 HydrophobicContact CE1-CG 4.31Å; F414-L439 HydrophobicContact CB-CD1 4.08Å; F414-L439 HydrophobicContact CB-CG 4.23Å; F414-L439 HydrophobicContact CD1-CD1 4.39Å; F414-L439 HydrophobicContact CD1-CD2 3.65Å; F414-L439 HydrophobicContact CD1-CG 3.94Å; F414-L439 HydrophobicContact CE1-CD2 4.07Å; F414-L439 HydrophobicContact CG-CD1 4.35Å; F414-L439 HydrophobicContact CG-CD2 4.39Å; F414-L439 HydrophobicContact CG-CG 4.36Å; F414-A508 HydrophobicContact CE1-CB 3.67Å; F414-A508 HydrophobicContact CE2-CB 4.15Å; F414-A508 HydrophobicContact CZ-CB 3.43Å; F414-A508 VanDerWaalsContact CZ-CB 3.43Å
415A93.4Very high87.1Confident1 Ų158.5 Ų58.51%0.00834%0.335CS..EExtended strand (participates in β ladder)trans-120.3142.4167.500000109.8V419 L424 L427 I436 F437 V438 L439A415-V419 HydrophobicContact CB-CB 3.98Å; A415-V419 HydrophobicContact CB-CG1 3.9Å; A415-V419 HydrophobicContact CB-CG2 4.02Å; A415-L424 HydrophobicContact CB-CD2 4.13Å; A415-L427 HydrophobicContact CB-CD1 3.75Å; A415-I436 HydrophobicContact CB-CG2 3.72Å; A415-F437 PolarHBondContact N-O 3.34Å; A415-V438 WeakPolarHBondContact O-CA 3.36Å; A415-L439 PolarHBondContact O-N 3.01Å
416P93.6Very high87.3Confident65 Ų6561.8 Ų61.842%0.42235%0.348SS..  trans-67.7157.7169.631.8-35.6000110.6N418 V419P416-N418 WeakPolarHBondContact CB-OD1 3.4Å; P416-N418 PolarHBondContact O-N 3.35Å; P416-V419 HydrophobicContact CG-CB 4.26Å; P416-V419 VanDerWaalsContact O-CB 3.22Å; P416-V419 WeakPolarHBondContact O-CB 3.15Å; P416-V419 WeakPolarHBondContact O-CG1 3.24Å; P416-V419 PolarHBondContact O-N 3.4Å
417F92Very high87.6Confident44 Ų4459.6 Ų59.619%0.19333%0.333CS..THydrogen-bonded Turntrans-56.9-34.7-179.4-163.6-109000113.5V419 V438 L439 E441 V447 V468 E469F417-V419 VanDerWaalsContact C-N 3.25Å; F417-V419 PolarHBondContact O-N 2.97Å; F417-V438 HydrophobicContact CD2-CG1 4.08Å; F417-L439 WeakPolarHBondContact CA-O 3.21Å; F417-L439 VanDerWaalsContact CB-O 3.29Å; F417-L439 WeakPolarHBondContact CB-O 3.49Å; F417-L439 PolarHBondContact N-O 3.14Å; F417-E441 HydrophobicContact CB-CG 4.12Å; F417-E441 HydrophobicContact CD1-CG 3.59Å; F417-E441 HydrophobicContact CE1-CG 4.25Å; F417-E441 HydrophobicContact CG-CG 4.01Å; F417-V447 HydrophobicContact CD2-CG2 3.93Å; F417-V447 HydrophobicContact CE2-CG2 4.08Å; F417-V468 HydrophobicContact CD2-CG1 4.42Å; F417-V468 VanDerWaalsContact O-CG1 3.25Å; F417-V468 WeakPolarHBondContact O-CG1 3.22Å; F417-E469 HydrophobicContact CE2-CG 4.03Å; F417-E469 HydrophobicContact CZ-CG 3.63Å; F417-E469 WeakPolarHBondContact CZ-OE1 3.25Å
418N92Very high87.7Confident132 Ų13258.8 Ų58.871%0.70633%0.33SS*.THydrogen-bonded Turntrans-87.320.4179.468.8-14.2000113.9P416 T420P416-N418 WeakPolarHBondContact CB-OD1 3.4Å; P416-N418 PolarHBondContact O-N 3.35Å; N418-T420 PolarHBondContact O-N 3.41Å
419V91.9Very high88Confident6 Ų661.3 Ų61.34%0.03632%0.324CS..  trans-60.8133.1-179.467.40000111.1A415 P416 F417 Q423 L424 L427 F466 V468A415-V419 HydrophobicContact CB-CB 3.98Å; A415-V419 HydrophobicContact CB-CG1 3.9Å; A415-V419 HydrophobicContact CB-CG2 4.02Å; P416-V419 HydrophobicContact CG-CB 4.26Å; P416-V419 VanDerWaalsContact O-CB 3.22Å; P416-V419 WeakPolarHBondContact O-CB 3.15Å; P416-V419 WeakPolarHBondContact O-CG1 3.24Å; P416-V419 PolarHBondContact O-N 3.4Å; F417-V419 VanDerWaalsContact C-N 3.25Å; F417-V419 PolarHBondContact O-N 2.97Å; V419-Q423 HydrophobicContact CG2-CB 3.53Å; V419-L424 HydrophobicContact CB-CG 4.37Å; V419-L424 HydrophobicContact CG1-CD1 3.77Å; V419-L424 HydrophobicContact CG1-CD2 3.95Å; V419-L424 HydrophobicContact CG1-CG 3.66Å; V419-L424 HydrophobicContact CG2-CD2 4.26Å; V419-L424 HydrophobicContact CG2-CG 3.79Å; V419-L427 HydrophobicContact CG2-CD1 4.33Å; V419-F466 WeakPolarHBondContact O-CE1 3.42Å; V419-V468 HydrophobicContact CG1-CB 4.04Å; V419-V468 HydrophobicContact CG1-CG2 3.99Å
420T90Very high88.6Confident62 Ų6267.7 Ų67.738%0.3835%0.35SS..  trans-79.5156.5174.760.60000111.3N418 S422 Q423 L424N418-T420 PolarHBondContact O-N 3.41Å; T420-S422 PolarHBondContact O-N 3.09Å; T420-S422 PolarHBondContact OG1-OG 3.13Å; T420-Q423 PolarHBondContact O-N 3.15Å; T420-Q423 WeakPolarHBondContact OG1-CB 3.34Å; T420-Q423 WeakPolarHBondContact OG1-CG 3.39Å; T420-Q423 PolarHBondContact OG1-N 2.94Å; T420-Q423 PolarHBondContact OG1-OE1 3.37Å; T420-L424 PolarHBondContact O-N 2.97Å
421Y88.9Confident89.2Confident40 Ų4063.4 Ų63.416%0.15733%0.327CS..Hα-helixtrans-55.9-38.3176.3-175.5-98.2000112.4L424 L425 L455 M458 P461 F466Y421-L424 PolarHBondContact O-N 3.28Å; Y421-L425 HydrophobicContact CD1-CD1 3.79Å; Y421-L425 HydrophobicContact CD1-CG 4.36Å; Y421-L425 HydrophobicContact CE1-CD1 3.34Å; Y421-L425 HydrophobicContact CE1-CG 3.98Å; Y421-L425 PolarHBondContact O-N 3.14Å; Y421-L455 HydrophobicContact CD2-CD2 3.86Å; Y421-L455 HydrophobicContact CE2-CD2 3.62Å; Y421-L455 PolarHBondContact OH-O 3.06Å; Y421-M458 HydrophobicContact CD2-SD 4.49Å; Y421-M458 HydrophobicContact CE2-CB 4.18Å; Y421-M458 HydrophobicContact CE2-SD 4.3Å; Y421-M458 PolarHBondContact OH-O 2.82Å; Y421-P461 HydrophobicContact CD1-CG 4.2Å; Y421-P461 HydrophobicContact CD2-CG 3.7Å; Y421-P461 HydrophobicContact CE1-CG 4.49Å; Y421-P461 HydrophobicContact CE2-CG 4.05Å; Y421-P461 HydrophobicContact CG-CG 3.8Å; Y421-F466 HydrophobicContact CD2-CD2 4.03Å; Y421-F466 AromaticContact CD2-CE2 3.9Å; Y421-F466 HydrophobicContact CD2-CE2 3.9Å; Y421-F466 HydrophobicContact CD2-CZ 4.32Å
422S87.3Confident89.3Confident71 Ų7164.3 Ų64.350%0.49733%0.327SS..Hα-helixtrans-67.4-37.2176.550.90000113T420 Q426T420-S422 PolarHBondContact O-N 3.09Å; T420-S422 PolarHBondContact OG1-OG 3.13Å; S422-Q426 WeakPolarHBondContact O-CG 3.19Å; S422-Q426 PolarHBondContact O-N 3.32Å; S422-Q426 VanDerWaalsContact O-N 3.14Å
423Q90.6Very high89Confident87 Ų8769.4 Ų69.441%0.40735%0.353SS..Hα-helixtrans-67.9-41.1173.1-74.7165-32.900111.5V419 T420 L425 Q426 L427V419-Q423 HydrophobicContact CG2-CB 3.53Å; T420-Q423 PolarHBondContact O-N 3.15Å; T420-Q423 WeakPolarHBondContact OG1-CB 3.34Å; T420-Q423 WeakPolarHBondContact OG1-CG 3.39Å; T420-Q423 PolarHBondContact OG1-N 2.94Å; T420-Q423 PolarHBondContact OG1-OE1 3.37Å; Q423-L425 PolarHBondContact O-N 2.97Å; Q423-Q426 WeakPolarHBondContact O-CB 3.44Å; Q423-Q426 PolarHBondContact O-N 2.95Å; Q423-Q426 VanDerWaalsContact O-N 3.12Å; Q423-L427 WeakPolarHBondContact O-CG 3.25Å; Q423-L427 PolarHBondContact O-N 3.45Å
424L90.9Very high88.8Confident0 Ų069.8 Ų69.80%035%0.354CS..Hα-helixtrans-60.3-43.8174-82.3169.7000111.9A415 V419 T420 Y421 Q426 L427 T428 I436 L455 F466 V468 I471A415-L424 HydrophobicContact CB-CD2 4.13Å; V419-L424 HydrophobicContact CB-CG 4.37Å; V419-L424 HydrophobicContact CG1-CD1 3.77Å; V419-L424 HydrophobicContact CG1-CD2 3.95Å; V419-L424 HydrophobicContact CG1-CG 3.66Å; V419-L424 HydrophobicContact CG2-CD2 4.26Å; V419-L424 HydrophobicContact CG2-CG 3.79Å; T420-L424 PolarHBondContact O-N 2.97Å; Y421-L424 PolarHBondContact O-N 3.28Å; L424-Q426 PolarHBondContact O-N 2.99Å; L424-L427 CarbonylContact O-C 3.59Å; L424-L427 PolarHBondContact O-N 3.04Å; L424-L427 VanDerWaalsContact O-N 3.07Å; L424-T428 PolarHBondContact O-N 3.15Å; L424-I436 HydrophobicContact CD2-CB 4.48Å; L424-I436 HydrophobicContact CD2-CD1 4.01Å; L424-I436 HydrophobicContact CD2-CG2 4.05Å; L424-L455 HydrophobicContact CB-CD1 4.11Å; L424-L455 HydrophobicContact CB-CD2 3.8Å; L424-L455 HydrophobicContact CD1-CD2 4.16Å; L424-F466 HydrophobicContact CD1-CE1 3.72Å; L424-F466 HydrophobicContact CD1-CZ 3.5Å; L424-F466 VanDerWaalsContact CD1-CZ 3.5Å; L424-V468 HydrophobicContact CD1-CG2 4Å; L424-I471 HydrophobicContact CD1-CD1 4.27Å
425L87.3Confident88.7Confident76 Ų7667.2 Ų67.240%0.39834%0.343SS..Hα-helixtrans-63.2-26.7174.4-81.3175.3000113.9Y421 Q423 T428Y421-L425 HydrophobicContact CD1-CD1 3.79Å; Y421-L425 HydrophobicContact CD1-CG 4.36Å; Y421-L425 HydrophobicContact CE1-CD1 3.34Å; Y421-L425 HydrophobicContact CE1-CG 3.98Å; Y421-L425 PolarHBondContact O-N 3.14Å; Q423-L425 PolarHBondContact O-N 2.97Å; L425-T428 PolarHBondContact O-OG1 2.85Å
426Q88.9Confident88.6Confident140 Ų14067.2 Ų67.265%0.65434%0.343SS*.Hα-helixtrans-77.6-38171.5-72176.61.600111S422 Q423 L424 T428 K429S422-Q426 WeakPolarHBondContact O-CG 3.19Å; S422-Q426 PolarHBondContact O-N 3.32Å; S422-Q426 VanDerWaalsContact O-N 3.14Å; Q423-Q426 WeakPolarHBondContact O-CB 3.44Å; Q423-Q426 PolarHBondContact O-N 2.95Å; Q423-Q426 VanDerWaalsContact O-N 3.12Å; L424-Q426 PolarHBondContact O-N 2.99Å; Q426-T428 VanDerWaalsContact C-N 3.34Å; Q426-T428 PolarHBondContact O-N 3.17Å; Q426-K429 PolarHBondContact O-N 3.4Å
427L91.4Very high88.6Confident36 Ų3664.1 Ų64.119%0.18832%0.323CS..Hα-helixtrans-68.5-29.5178.7-72.1170.9000112.7V413 A415 V419 Q423 L424 K429 K430 A431 I436V413-L427 HydrophobicContact CG1-CB 4.02Å; V413-L427 HydrophobicContact CG1-CD2 3.59Å; V413-L427 HydrophobicContact CG1-CG 4.26Å; A415-L427 HydrophobicContact CB-CD1 3.75Å; V419-L427 HydrophobicContact CG2-CD1 4.33Å; Q423-L427 WeakPolarHBondContact O-CG 3.25Å; Q423-L427 PolarHBondContact O-N 3.45Å; L424-L427 CarbonylContact O-C 3.59Å; L424-L427 PolarHBondContact O-N 3.04Å; L424-L427 VanDerWaalsContact O-N 3.07Å; L427-K429 VanDerWaalsContact C-N 3.25Å; L427-K429 PolarHBondContact O-N 2.95Å; L427-K430 CarbonylContact O-C 3.54Å; L427-K430 WeakPolarHBondContact O-CA 3.33Å; L427-K430 WeakPolarHBondContact O-CB 3.45Å; L427-K430 PolarHBondContact O-N 3.14Å; L427-A431 WeakPolarHBondContact O-CB 3.5Å; L427-A431 PolarHBondContact O-N 2.92Å; L427-I436 HydrophobicContact CB-CD1 3.75Å; L427-I436 HydrophobicContact CB-CG1 4.39Å; L427-I436 HydrophobicContact CD1-CG2 4.38Å
428T86.6Confident88.6Confident30 Ų3062 Ų6218%0.18431%0.314CS..Hα-helixtrans-59.6-36.3175.2460000112.3L424 L425 Q426 K430 A431 N432 I436 L455L424-T428 PolarHBondContact O-N 3.15Å; L425-T428 PolarHBondContact O-OG1 2.85Å; Q426-T428 VanDerWaalsContact C-N 3.34Å; Q426-T428 PolarHBondContact O-N 3.17Å; T428-K430 VanDerWaalsContact C-N 3.32Å; T428-K430 PolarHBondContact O-N 3.35Å; T428-A431 PolarHBondContact O-N 2.82Å; T428-N432 PolarHBondContact O-N 2.81Å; T428-N432 VanDerWaalsContact O-N 3.11Å; T428-I436 HydrophobicContact CG2-CD1 3.75Å; T428-L455 HydrophobicContact CG2-CD1 3.4Å
429K85.3Confident88.5Confident182 Ų18257.1 Ų57.179%0.79129%0.287SS*.Hα-helixtrans-63.6-38.3173.2-65.7-176.1179.4-1790112.2Q426 L427Q426-K429 PolarHBondContact O-N 3.4Å; L427-K429 VanDerWaalsContact C-N 3.25Å; L427-K429 PolarHBondContact O-N 2.95Å
430K86.4Confident88.3Confident162 Ų16258.1 Ų58.170%0.70429%0.293SS*.Hα-helixtrans-73.4-33.8177.2-168.7179.4178.3-1770111.7V413 L427 T428 N432V413-K430 HydrophobicContact CG2-CB 4.26Å; V413-K430 HydrophobicContact CG2-CD 4.34Å; V413-K430 HydrophobicContact CG2-CG 3.97Å; L427-K430 CarbonylContact O-C 3.54Å; L427-K430 WeakPolarHBondContact O-CA 3.33Å; L427-K430 WeakPolarHBondContact O-CB 3.45Å; L427-K430 PolarHBondContact O-N 3.14Å; T428-K430 VanDerWaalsContact C-N 3.32Å; T428-K430 PolarHBondContact O-N 3.35Å; K430-N432 VanDerWaalsContact C-N 3.28Å; K430-N432 PolarHBondContact O-N 3.01Å
431A86.6Confident88.1Confident3 Ų363.2 Ų63.23%0.02531%0.312CS..Hα-helixtrans-75.9-16.9-179.300000112.7V413 L427 T428 N433 K434 I436V413-A431 HydrophobicContact CB-CB 4Å; V413-A431 HydrophobicContact CG2-CB 3.85Å; L427-A431 WeakPolarHBondContact O-CB 3.5Å; L427-A431 PolarHBondContact O-N 2.92Å; T428-A431 PolarHBondContact O-N 2.82Å; A431-N433 PolarHBondContact O-N 2.87Å; A431-K434 WeakPolarHBondContact CB-O 3.18Å; A431-K434 WeakPolarHBondContact O-CB 3.46Å; A431-K434 VanDerWaalsContact O-CG 3.24Å; A431-K434 WeakPolarHBondContact O-CG 3.41Å; A431-K434 PolarHBondContact O-N 3.35Å; A431-I436 HydrophobicContact CB-CG1 3.93Å
432N84.1Confident87.9Confident119 Ų11964.4 Ų64.464%0.63633%0.33SS*.THydrogen-bonded Turntrans51.256.1177.5-165.136.7000112.3T428 K430 K434T428-N432 PolarHBondContact O-N 2.81Å; T428-N432 VanDerWaalsContact O-N 3.11Å; K430-N432 VanDerWaalsContact C-N 3.28Å; K430-N432 PolarHBondContact O-N 3.01Å; N432-K434 PolarHBondContact O-N 3.16Å
433N78.6Confident87.7Confident129 Ų12963.1 Ų63.169%0.6933%0.328SS*.THydrogen-bonded Turntrans64.29.4-174.4-62.6-14000116.2A431A431-N433 PolarHBondContact O-N 2.87Å
434K86.1Confident87Confident20 Ų2066.2 Ų66.29%0.08734%0.342CS..SBendtrans-84.7157.4172.1-59.5171.6175.6-1620111.1D410 A431 N432 V512D410-K434 VanDerWaalsContact CB-NZ 3.33Å; D410-K434 IonicContact OD2-NZ 3.47Å; D410-K434 PolarHBondContact OD2-NZ 2.86Å; A431-K434 WeakPolarHBondContact CB-O 3.18Å; A431-K434 WeakPolarHBondContact O-CB 3.46Å; A431-K434 VanDerWaalsContact O-CG 3.24Å; A431-K434 WeakPolarHBondContact O-CG 3.41Å; A431-K434 PolarHBondContact O-N 3.35Å; N432-K434 PolarHBondContact O-N 3.16Å; K434-V512 HydrophobicContact CB-CB 4.47Å; K434-V512 HydrophobicContact CB-CG1 4.17Å; K434-V512 HydrophobicContact CD-CB 3.98Å; K434-V512 HydrophobicContact CD-CG1 4.07Å; K434-V512 HydrophobicContact CG-CB 4.31Å; K434-V512 HydrophobicContact CG-CG1 3.91Å; K434-V512 PolarHBondContact NZ-O 3.39Å; K434-V512 VanDerWaalsContact NZ-O 3.07Å
435P89.8Confident86.4Confident6 Ų673 Ų734%0.03937%0.368CS..PPolyproline II helixtrans-56.6140.5172.5-17.925.7000111.8F437 C449 L451 F497P435-F437 HydrophobicContact CB-CE2 4.43Å; P435-F437 HydrophobicContact CB-CZ 4.26Å; P435-C449 HydrophobicContact CB-CB 4.1Å; P435-L451 HydrophobicContact CB-CD2 3.97Å; P435-L451 HydrophobicContact CG-CD2 3.71Å; P435-F497 HydrophobicContact CB-CE1 4.44Å; P435-F497 HydrophobicContact CB-CE2 4.4Å; P435-F497 HydrophobicContact CB-CZ 4.35Å; P435-F497 HydrophobicContact CG-CB 4.1Å; P435-F497 HydrophobicContact CG-CD1 3.56Å; P435-F497 HydrophobicContact CG-CD2 3.68Å; P435-F497 HydrophobicContact CG-CE1 3.88Å; P435-F497 HydrophobicContact CG-CE2 3.97Å; P435-F497 HydrophobicContact CG-CG 3.47Å; P435-F497 VanDerWaalsContact CG-CG 3.47Å; P435-F497 HydrophobicContact CG-CZ 4.07Å
436I92.5Very high86.3Confident1 Ų170.1 Ų70.11%0.00535%0.353CS..EExtended strand (participates in β ladder)trans-94117.6169.6-59.6163.8000107.6V413 A415 L424 L427 T428 A431 C449 V450 L455V413-I436 HydrophobicContact CG1-CG2 4.39Å; V413-I436 WeakPolarHBondContact O-CA 3.44Å; A415-I436 HydrophobicContact CB-CG2 3.72Å; L424-I436 HydrophobicContact CD2-CB 4.48Å; L424-I436 HydrophobicContact CD2-CD1 4.01Å; L424-I436 HydrophobicContact CD2-CG2 4.05Å; L427-I436 HydrophobicContact CB-CD1 3.75Å; L427-I436 HydrophobicContact CB-CG1 4.39Å; L427-I436 HydrophobicContact CD1-CG2 4.38Å; T428-I436 HydrophobicContact CG2-CD1 3.75Å; A431-I436 HydrophobicContact CB-CG1 3.93Å; I436-C449 CarbonylContact O-C 3.55Å; I436-C449 VanDerWaalsContact O-CA 3.27Å; I436-C449 WeakPolarHBondContact O-CA 3.48Å; I436-V450 PolarHBondContact N-O 3.16Å; I436-V450 PolarHBondContact O-N 2.69Å; I436-L455 HydrophobicContact CD1-CD1 4.38Å
437F92.4Very high86.3Confident0 Ų065.2 Ų65.20%033%0.333CS..EExtended strand (participates in β ladder)trans-83127.9-179.2-67.1-77.9000110.6P412 V413 F414 A415 P435 T446 C449 F476 F497 A499 T510 V512P412-F437 HydrophobicContact CB-CD2 3.68Å; P412-F437 HydrophobicContact CB-CE2 3.97Å; V413-F437 PolarHBondContact O-N 2.86Å; F414-F437 CarbonylContact C-O 3.59Å; F414-F437 WeakPolarHBondContact CA-O 3.32Å; F414-F437 HydrophobicContact CD1-CB 3.56Å; F414-F437 HydrophobicContact CE1-CB 3.6Å; F414-F437 HydrophobicContact CE1-CG 4.31Å; A415-F437 PolarHBondContact N-O 3.34Å; P435-F437 HydrophobicContact CB-CE2 4.43Å; P435-F437 HydrophobicContact CB-CZ 4.26Å; F437-T446 HydrophobicContact CB-CG2 3.84Å; F437-T446 HydrophobicContact CD1-CG2 3.85Å; F437-T446 HydrophobicContact CG-CG2 4.28Å; F437-C449 HydrophobicContact CD1-CB 3.88Å; F437-C449 HydrophobicContact CE1-CB 4.06Å; F437-F476 HydrophobicContact CD1-CE2 4.21Å; F437-F476 AromaticContact CD1-CZ 3.98Å; F437-F476 HydrophobicContact CD1-CZ 3.98Å; F437-F476 HydrophobicContact CE1-CD2 4.22Å; F437-F476 AromaticContact CE1-CE2 3.79Å; F437-F476 HydrophobicContact CE1-CE2 3.79Å; F437-F476 HydrophobicContact CE1-CZ 4.01Å; F437-F497 HydrophobicContact CE1-CE2 4.06Å; F437-F497 HydrophobicContact CZ-CD2 4.42Å; F437-F497 HydrophobicContact CZ-CE2 4.09Å; F437-A499 HydrophobicContact CE1-CB 4.04Å; F437-A499 HydrophobicContact CZ-CB 4.09Å; F437-T510 HydrophobicContact CD1-CG2 4.23Å; F437-T510 HydrophobicContact CD2-CG2 4.06Å; F437-T510 HydrophobicContact CE1-CG2 3.7Å; F437-T510 HydrophobicContact CE2-CG2 3.51Å; F437-T510 HydrophobicContact CG-CG2 4.39Å; F437-T510 HydrophobicContact CZ-CG2 3.31Å; F437-V512 HydrophobicContact CE2-CG2 3.88Å; F437-V512 HydrophobicContact CZ-CG2 4.2Å
438V92.3Very high86.2Confident0 Ų063.5 Ų63.50%032%0.324CS..EExtended strand (participates in β ladder)trans-93.9123.8-178.4-175.60000108.5A415 F417 T446 V447 G448 V450 V468 M472A415-V438 WeakPolarHBondContact O-CA 3.36Å; F417-V438 HydrophobicContact CD2-CG1 4.08Å; V438-T446 CarbonylContact O-C 3.59Å; V438-T446 WeakPolarHBondContact O-CA 3.44Å; V438-V447 HydrophobicContact CB-CG2 4.3Å; V438-V447 HydrophobicContact CG1-CG2 4.06Å; V438-V447 WeakPolarHBondContact O-CG2 3.36Å; V438-V447 PolarHBondContact O-N 3.06Å; V438-G448 PolarHBondContact N-O 2.96Å; V438-V450 HydrophobicContact CG2-CG2 3.86Å; V438-V468 HydrophobicContact CG1-CG1 3.9Å; V438-V468 HydrophobicContact CG1-CG2 4.31Å; V438-V468 HydrophobicContact CG2-CG2 3.66Å; V438-M472 HydrophobicContact CB-SD 3.62Å; V438-M472 HydrophobicContact CG1-SD 3.9Å; V438-M472 HydrophobicContact CG2-CG 4.17Å; V438-M472 HydrophobicContact CG2-SD 3.84Å
439L91.1Very high86.4Confident29 Ų2962 Ų6215%0.15232%0.315CS..EExtended strand (participates in β ladder)trans-83.4151.7174.1-60.8174.5000110.3F414 A415 F417 R445 A508F414-L439 HydrophobicContact CB-CD1 4.08Å; F414-L439 HydrophobicContact CB-CG 4.23Å; F414-L439 HydrophobicContact CD1-CD1 4.39Å; F414-L439 HydrophobicContact CD1-CD2 3.65Å; F414-L439 HydrophobicContact CD1-CG 3.94Å; F414-L439 HydrophobicContact CE1-CD2 4.07Å; F414-L439 HydrophobicContact CG-CD1 4.35Å; F414-L439 HydrophobicContact CG-CD2 4.39Å; F414-L439 HydrophobicContact CG-CG 4.36Å; A415-L439 PolarHBondContact O-N 3.01Å; F417-L439 WeakPolarHBondContact CA-O 3.21Å; F417-L439 VanDerWaalsContact CB-O 3.29Å; F417-L439 WeakPolarHBondContact CB-O 3.49Å; F417-L439 PolarHBondContact N-O 3.14Å; L439-R445 CarbonylContact C-O 3.47Å; L439-R445 VanDerWaalsContact CA-O 3.3Å; L439-R445 WeakPolarHBondContact CA-O 3.22Å; L439-A508 HydrophobicContact CD2-CB 4.45Å
440N87.2Confident86.7Confident28 Ų2853.4 Ų53.415%0.1528%0.277CS..PPolyproline II helixtrans-60.3170.1169.570.5-24.5000111.4A442 G443 Q444 R445 V447N440-A442 PolarHBondContact O-N 2.82Å; N440-A442 VanDerWaalsContact O-N 3.13Å; N440-G443 WeakPolarHBondContact O-CA 3.35Å; N440-G443 PolarHBondContact O-N 3.49Å; N440-G443 PolarHBondContact OD1-N 3.47Å; N440-G443 VanDerWaalsContact OD1-N 3.15Å; N440-Q444 PolarHBondContact OD1-N 3.23Å; N440-R445 HydrophobicContact CB-CG 4Å; N440-R445 PolarHBondContact N-O 3Å; N440-R445 PolarHBondContact OD1-N 3.09Å; N440-R445 VanDerWaalsContact OD1-N 3.14Å; N440-R445 PolarHBondContact OD1-O 3.27Å; N440-V447 HydrophobicContact CB-CG1 3.54Å
441E86.3Confident86.8Confident169 Ų16946.9 Ų46.979%0.7925%0.25SS*.THydrogen-bonded Turntrans-55.1-33.2178.9-64.7-175.6162.300113.7F417 G443F417-E441 HydrophobicContact CB-CG 4.12Å; F417-E441 HydrophobicContact CD1-CG 3.59Å; F417-E441 HydrophobicContact CE1-CG 4.25Å; F417-E441 HydrophobicContact CG-CG 4.01Å; E441-G443 PolarHBondContact O-N 3.34Å
442A83.9Confident86.6Confident64 Ų6447.4 Ų47.453%0.52925%0.253SS..THydrogen-bonded Turntrans-74.9-9.917600000114N440 Q444N440-A442 PolarHBondContact O-N 2.82Å; N440-A442 VanDerWaalsContact O-N 3.13Å; A442-Q444 VanDerWaalsContact C-N 3.27Å; A442-Q444 HydrophobicContact CB-CB 4.46Å; A442-Q444 HydrophobicContact CB-CG 4.06Å; A442-Q444 PolarHBondContact O-N 2.86Å
443G82.8Confident86.6Confident44 Ų4446.9 Ų46.945%0.45425%0.247SC..SBendtrans70.917.7-177.400000114.6N440 E441N440-G443 WeakPolarHBondContact O-CA 3.35Å; N440-G443 PolarHBondContact O-N 3.49Å; N440-G443 PolarHBondContact OD1-N 3.47Å; N440-G443 VanDerWaalsContact OD1-N 3.15Å; E441-G443 PolarHBondContact O-N 3.34Å
444Q75.7Confident86.9Confident152 Ų15241.8 Ų41.871%0.7122%0.223SC*.SBendtrans-103.8-30.8-168.2-70.1180-33.300114.3N440 A442N440-Q444 PolarHBondContact OD1-N 3.23Å; A442-Q444 VanDerWaalsContact C-N 3.27Å; A442-Q444 HydrophobicContact CB-CB 4.46Å; A442-Q444 HydrophobicContact CB-CG 4.06Å; A442-Q444 PolarHBondContact O-N 2.86Å
445R79.5Confident86.6Confident144 Ų14440.9 Ų40.954%0.54322%0.219SC..SBendtrans-136.9147.6-177.569.9-179.6-175.2178.60.9111.1L439 N440 V447 H506L439-R445 CarbonylContact C-O 3.47Å; L439-R445 VanDerWaalsContact CA-O 3.3Å; L439-R445 WeakPolarHBondContact CA-O 3.22Å; N440-R445 HydrophobicContact CB-CG 4Å; N440-R445 PolarHBondContact N-O 3Å; N440-R445 PolarHBondContact OD1-N 3.09Å; N440-R445 VanDerWaalsContact OD1-N 3.14Å; N440-R445 PolarHBondContact OD1-O 3.27Å; R445-V447 HydrophobicContact CG-CG1 4.34Å; R445-H506 HydrophobicContact CB-CB 4.32Å
446T85.2Confident86Confident14 Ų1447.2 Ų47.29%0.08625%0.251CS..EExtended strand (participates in β ladder)trans-70.9130.9169.6-49.60000110.2F437 V438 G448 F476F437-T446 HydrophobicContact CB-CG2 3.84Å; F437-T446 HydrophobicContact CD1-CG2 3.85Å; F437-T446 HydrophobicContact CG-CG2 4.28Å; V438-T446 CarbonylContact O-C 3.59Å; V438-T446 WeakPolarHBondContact O-CA 3.44Å; T446-G448 VanDerWaalsContact CG2-O 3.27Å; T446-G448 WeakPolarHBondContact CG2-O 3.28Å; T446-F476 HydrophobicContact CG2-CE1 4.3Å; T446-F476 HydrophobicContact CG2-CZ 3.75Å
447V87.8Confident85.1Confident37 Ų3751.7 Ų51.722%0.22428%0.282CS..EExtended strand (participates in β ladder)trans-110.2-8.7178.4-67.70000113.4F417 V438 N440 R445 M472F417-V447 HydrophobicContact CD2-CG2 3.93Å; F417-V447 HydrophobicContact CE2-CG2 4.08Å; V438-V447 HydrophobicContact CB-CG2 4.3Å; V438-V447 HydrophobicContact CG1-CG2 4.06Å; V438-V447 WeakPolarHBondContact O-CG2 3.36Å; V438-V447 PolarHBondContact O-N 3.06Å; N440-V447 HydrophobicContact CB-CG1 3.54Å; R445-V447 HydrophobicContact CG-CG1 4.34Å; V447-M472 HydrophobicContact CG2-CE 4.24Å; V447-M472 HydrophobicContact CG2-SD 4Å
448G89.9Confident84Confident0 Ų053.5 Ų53.50%029%0.291CS..EExtended strand (participates in β ladder)trans174.3-176.4179.600000111.1V438 T446 M472 Q473V438-G448 PolarHBondContact N-O 2.96Å; T446-G448 VanDerWaalsContact CG2-O 3.27Å; T446-G448 WeakPolarHBondContact CG2-O 3.28Å; G448-M472 VanDerWaalsContact CA-SD 3.53Å; G448-Q473 CarbonylContact C-O 3.52Å; G448-Q473 WeakPolarHBondContact CA-O 3.09Å
449C91Very high82.4Confident0 Ų057.9 Ų57.90%033%0.327CS..EExtended strand (participates in β ladder)trans-135.1154.4170.764.30000111.1P435 I436 F437 M472 Q473 F476 F497P435-C449 HydrophobicContact CB-CB 4.1Å; I436-C449 CarbonylContact O-C 3.55Å; I436-C449 VanDerWaalsContact O-CA 3.27Å; I436-C449 WeakPolarHBondContact O-CA 3.48Å; F437-C449 HydrophobicContact CD1-CB 3.88Å; F437-C449 HydrophobicContact CE1-CB 4.06Å; C449-M472 CarbonylContact O-C 3.52Å; C449-M472 WeakPolarHBondContact O-CA 3.24Å; C449-Q473 PolarHBondContact N-O 3.12Å; C449-Q473 PolarHBondContact O-N 3.37Å; C449-F476 HydrophobicContact CB-CD1 4.25Å; C449-F476 HydrophobicContact CB-CE1 4.32Å; C449-F497 HydrophobicContact CB-CZ 4.36Å; C449-F497 WeakPolarHBondContact SG-CZ 2.9Å
450V91Very high80.9Confident0 Ų063.9 Ų63.90%036%0.355CS..EExtended strand (participates in β ladder)trans-112.3120.4171.3-179.60000108I436 V438 L455 V468 I471 M472I436-V450 PolarHBondContact N-O 3.16Å; I436-V450 PolarHBondContact O-N 2.69Å; V438-V450 HydrophobicContact CG2-CG2 3.86Å; V450-L455 HydrophobicContact CG1-CD1 3.75Å; V450-L455 HydrophobicContact CG1-CG 3.75Å; V450-V468 HydrophobicContact CG2-CG2 3.64Å; V450-I471 HydrophobicContact CG1-CD1 3.67Å; V450-I471 HydrophobicContact CG1-CG1 4.19Å; V450-I471 HydrophobicContact CG2-CD1 4.41Å; V450-I471 HydrophobicContact CG2-CG1 4.26Å; V450-M472 HydrophobicContact CG2-CB 4.28Å
451L88.7Confident79.3Confident25 Ų2563.5 Ų63.513%0.13135%0.354CS..  trans-82.2147.6173.5-67.5173.9000110.7P435 E453 A454 L455 E496 F497P435-L451 HydrophobicContact CB-CD2 3.97Å; P435-L451 HydrophobicContact CG-CD2 3.71Å; L451-E453 WeakPolarHBondContact CB-OE2 3.23Å; L451-E453 PolarHBondContact O-N 3.08Å; L451-A454 WeakPolarHBondContact O-CB 3.49Å; L451-A454 PolarHBondContact O-N 3.38Å; L451-A454 VanDerWaalsContact O-N 3.1Å; L451-L455 PolarHBondContact O-N 2.93Å; L451-E496 WeakPolarHBondContact CD1-OE2 3.16Å; L451-F497 HydrophobicContact CD2-CD1 3.83Å; L451-F497 HydrophobicContact CD2-CE1 3.7Å; L451-F497 HydrophobicContact CG-CE1 4.42Å
452P83.6Confident77.8Confident14 Ų1461 Ų619%0.09135%0.351CS..Hα-helixtrans-54.3-37.2177.7-2534.2000113.4A454 L455 I456P452-A454 VanDerWaalsContact C-N 3.31Å; P452-A454 PolarHBondContact O-N 3.38Å; P452-L455 PolarHBondContact O-N 2.77Å; P452-I456 WeakPolarHBondContact O-CG1 3.5Å; P452-I456 PolarHBondContact O-N 2.9Å
453E83.2Confident76.5Confident108 Ų10866.7 Ų66.751%0.50536%0.363SS..Hα-helixtrans-64.4-35.6179.4-58.975.3-155.400112L451 L455 I456 S457L451-E453 WeakPolarHBondContact CB-OE2 3.23Å; L451-E453 PolarHBondContact O-N 3.08Å; E453-L455 VanDerWaalsContact C-N 3.3Å; E453-L455 PolarHBondContact O-N 2.96Å; E453-I456 PolarHBondContact O-N 3.02Å; E453-S457 WeakPolarHBondContact O-CB 3.43Å; E453-S457 PolarHBondContact O-N 3.32Å; E453-S457 PolarHBondContact O-OG 2.91Å
454A84.4Confident75.3Confident22 Ų2271.7 Ų71.718%0.18238%0.379CS..Hα-helixtrans-66.2-32.8178.100000112.1L451 P452 S457 M458 I471L451-A454 WeakPolarHBondContact O-CB 3.49Å; L451-A454 PolarHBondContact O-N 3.38Å; L451-A454 VanDerWaalsContact O-N 3.1Å; P452-A454 VanDerWaalsContact C-N 3.31Å; P452-A454 PolarHBondContact O-N 3.38Å; A454-S457 PolarHBondContact O-OG 3.48Å; A454-M458 PolarHBondContact O-N 2.88Å; A454-I471 HydrophobicContact CB-CB 4.24Å
455L81.5Confident75.4Confident2 Ų271 Ų711%0.0138%0.381CS..Hα-helixtrans-72.7-35174-82.1159000112.6Y421 L424 T428 I436 V450 L451 P452 E453 I471Y421-L455 HydrophobicContact CD2-CD2 3.86Å; Y421-L455 HydrophobicContact CE2-CD2 3.62Å; Y421-L455 PolarHBondContact OH-O 3.06Å; L424-L455 HydrophobicContact CB-CD1 4.11Å; L424-L455 HydrophobicContact CB-CD2 3.8Å; L424-L455 HydrophobicContact CD1-CD2 4.16Å; T428-L455 HydrophobicContact CG2-CD1 3.4Å; I436-L455 HydrophobicContact CD1-CD1 4.38Å; V450-L455 HydrophobicContact CG1-CD1 3.75Å; V450-L455 HydrophobicContact CG1-CG 3.75Å; L451-L455 PolarHBondContact O-N 2.93Å; P452-L455 PolarHBondContact O-N 2.77Å; E453-L455 VanDerWaalsContact C-N 3.3Å; E453-L455 PolarHBondContact O-N 2.96Å; L455-I471 HydrophobicContact CD2-CD1 3.73Å; L455-I471 HydrophobicContact CG-CD1 3.97Å
456I76.4Confident75.6Confident138 Ų13865.9 Ų65.971%0.70836%0.363SS*.Hα-helixtrans-75.7-37.8-179.8-64166.4000111.1P452 E453 M458P452-I456 WeakPolarHBondContact O-CG1 3.5Å; P452-I456 PolarHBondContact O-N 2.9Å; E453-I456 PolarHBondContact O-N 3.02Å; I456-M458 VanDerWaalsContact C-N 3.28Å; I456-M458 PolarHBondContact O-N 2.84Å
457S73.1Confident75.7Confident95 Ų9567 Ų6766%0.66437%0.371SS*.Hα-helixtrans-70.4-24.4-179.864.80000113E453 A454 A459E453-S457 WeakPolarHBondContact O-CB 3.43Å; E453-S457 PolarHBondContact O-N 3.32Å; E453-S457 PolarHBondContact O-OG 2.91Å; A454-S457 PolarHBondContact O-OG 3.48Å; S457-A459 PolarHBondContact O-N 2.84Å
458M70.4Confident75.7Confident38 Ų3865.4 Ų65.419%0.18736%0.361CS..SBendtrans-69.491.2164.1-80.4-164.183.800110.6Y421 A454 I456 Q460 P461 F466 I471Y421-M458 HydrophobicContact CD2-SD 4.49Å; Y421-M458 HydrophobicContact CE2-CB 4.18Å; Y421-M458 HydrophobicContact CE2-SD 4.3Å; Y421-M458 PolarHBondContact OH-O 2.82Å; A454-M458 PolarHBondContact O-N 2.88Å; I456-M458 VanDerWaalsContact C-N 3.28Å; I456-M458 PolarHBondContact O-N 2.84Å; M458-Q460 PolarHBondContact O-N 2.68Å; M458-P461 HydrophobicContact CE-CB 3.44Å; M458-P461 VanDerWaalsContact CE-CB 3.44Å; M458-P461 HydrophobicContact CE-CG 3.48Å; M458-P461 VanDerWaalsContact CE-CG 3.48Å; M458-P461 HydrophobicContact SD-CG 4.41Å; M458-F466 HydrophobicContact CE-CD2 4Å; M458-F466 HydrophobicContact CE-CE2 4.33Å; M458-F466 HydrophobicContact SD-CD2 4.03Å; M458-F466 HydrophobicContact SD-CE2 3.76Å; M458-I471 HydrophobicContact CG-CG2 3.53Å; M458-I471 HydrophobicContact SD-CB 4.43Å; M458-I471 HydrophobicContact SD-CD1 4.24Å; M458-I471 HydrophobicContact SD-CG2 3.18Å; M458-I471 WeakPolarHBondContact SD-CG2 3.36Å
459A59Low75.6Confident92 Ų9271 Ų7176%0.7639%0.387SS*.  trans-50.7116.1160.300000108.1S457 P461S457-A459 PolarHBondContact O-N 2.84Å; A459-P461 VanDerWaalsContact O-N 3.15Å
460Q57.6Low75.4Confident156 Ų15676.9 Ų76.973%0.72942%0.415SS*.  trans-13.5104.7-167.9-75.3-163-2.300113.2M458 T462M458-Q460 PolarHBondContact O-N 2.68Å; Q460-T462 PolarHBondContact O-N 2.62Å
461P55.1Low75.2Confident19 Ų1978 Ų7812%0.12342%0.42CS..  trans-53.7134.8173.915.6-22.4000107.6Y421 M458 A459 K463 F466Y421-P461 HydrophobicContact CD1-CG 4.2Å; Y421-P461 HydrophobicContact CD2-CG 3.7Å; Y421-P461 HydrophobicContact CE1-CG 4.49Å; Y421-P461 HydrophobicContact CE2-CG 4.05Å; Y421-P461 HydrophobicContact CG-CG 3.8Å; M458-P461 HydrophobicContact CE-CB 3.44Å; M458-P461 VanDerWaalsContact CE-CB 3.44Å; M458-P461 HydrophobicContact CE-CG 3.48Å; M458-P461 VanDerWaalsContact CE-CG 3.48Å; M458-P461 HydrophobicContact SD-CG 4.41Å; A459-P461 VanDerWaalsContact O-N 3.15Å; P461-K463 WeakPolarHBondContact O-CA 3.39Å; P461-K463 PolarHBondContact O-N 3.12Å; P461-F466 HydrophobicContact CB-CB 4.47Å; P461-F466 HydrophobicContact CG-CB 4.39Å; P461-F466 HydrophobicContact CG-CD2 4.09Å
462T54.9Low75.2Confident118 Ų11878.2 Ų78.272%0.72442%0.421SS*.  trans-42.7112.4164.746.30000106.5Q460 D464 N465Q460-T462 PolarHBondContact O-N 2.62Å; T462-D464 PolarHBondContact O-N 3.19Å; T462-N465 PolarHBondContact O-N 3.16Å
463K55Low75.3Confident183 Ų18381.1 Ų81.180%0.79643%0.434SS*.THydrogen-bonded Turntrans-53.2-8.6-158-86.8178.6173.8175.50115.6P461P461-K463 WeakPolarHBondContact O-CA 3.39Å; P461-K463 PolarHBondContact O-N 3.12Å
464D59.3Low75.2Confident148 Ų14879.6 Ų79.679%0.79143%0.433SS*.THydrogen-bonded Turntrans-104.6-6.1-166.3-55.7-33.5000114.7T462T462-D464 PolarHBondContact O-N 3.19Å
465N76.4Confident75Confident139 Ų13985.8 Ų85.874%0.74346%0.458SS*.  trans-136.723.3-175.1-96.9-2.1000116.3T462 S467T462-N465 PolarHBondContact O-N 3.16Å; N465-S467 PolarHBondContact O-N 2.68Å
466F84.1Confident75Confident36 Ų3687.6 Ų87.616%0.15847%0.466CS..  trans-70.7129.6178.3173.9-99.6000112.2V419 Y421 L424 M458 P461 V468 I471V419-F466 WeakPolarHBondContact O-CE1 3.42Å; Y421-F466 HydrophobicContact CD2-CD2 4.03Å; Y421-F466 AromaticContact CD2-CE2 3.9Å; Y421-F466 HydrophobicContact CD2-CE2 3.9Å; Y421-F466 HydrophobicContact CD2-CZ 4.32Å; L424-F466 HydrophobicContact CD1-CE1 3.72Å; L424-F466 HydrophobicContact CD1-CZ 3.5Å; L424-F466 VanDerWaalsContact CD1-CZ 3.5Å; M458-F466 HydrophobicContact CE-CD2 4Å; M458-F466 HydrophobicContact CE-CE2 4.33Å; M458-F466 HydrophobicContact SD-CD2 4.03Å; M458-F466 HydrophobicContact SD-CE2 3.76Å; P461-F466 HydrophobicContact CB-CB 4.47Å; P461-F466 HydrophobicContact CG-CB 4.39Å; P461-F466 HydrophobicContact CG-CD2 4.09Å; F466-V468 HydrophobicContact CE1-CB 4.35Å; F466-V468 HydrophobicContact CZ-CB 4.37Å; F466-I471 HydrophobicContact CE2-CD1 3.75Å; F466-I471 HydrophobicContact CE2-CG1 4.05Å; F466-I471 HydrophobicContact CZ-CD1 3.76Å; F466-I471 HydrophobicContact CZ-CG1 4.12Å
467S87.1Confident75.2Confident38 Ų3883.7 Ų83.727%0.26644%0.444SS..  trans-119.3137.4162.3172.90000109.1N465 E469 Q470N465-S467 PolarHBondContact O-N 2.68Å; S467-E469 PolarHBondContact O-N 3.11Å; S467-E469 PolarHBondContact OG-N 3.19Å; S467-E469 PolarHBondContact OG-OE2 3.37Å; S467-Q470 VanDerWaalsContact O-CB 3.32Å; S467-Q470 WeakPolarHBondContact O-CB 3.36Å; S467-Q470 WeakPolarHBondContact O-CG 3.3Å; S467-Q470 PolarHBondContact O-N 2.64Å; S467-Q470 PolarHBondContact O-OE1 3.32Å
468V88.3Confident75.7Confident2 Ų282.5 Ų82.51%0.01243%0.433CS..G310 helixtrans-59.8-29178.470.60000112.2F417 V419 L424 V438 V450 F466 Q470 I471 M472F417-V468 HydrophobicContact CD2-CG1 4.42Å; F417-V468 VanDerWaalsContact O-CG1 3.25Å; F417-V468 WeakPolarHBondContact O-CG1 3.22Å; V419-V468 HydrophobicContact CG1-CB 4.04Å; V419-V468 HydrophobicContact CG1-CG2 3.99Å; L424-V468 HydrophobicContact CD1-CG2 4Å; V438-V468 HydrophobicContact CG1-CG1 3.9Å; V438-V468 HydrophobicContact CG1-CG2 4.31Å; V438-V468 HydrophobicContact CG2-CG2 3.66Å; V450-V468 HydrophobicContact CG2-CG2 3.64Å; F466-V468 HydrophobicContact CE1-CB 4.35Å; F466-V468 HydrophobicContact CZ-CB 4.37Å; V468-Q470 PolarHBondContact O-N 2.72Å; V468-Q470 VanDerWaalsContact O-N 3.11Å; V468-I471 WeakPolarHBondContact O-CG1 3.37Å; V468-I471 PolarHBondContact O-N 3.21Å; V468-I471 VanDerWaalsContact O-N 3.09Å; V468-M472 HydrophobicContact CG2-CB 4.44Å; V468-M472 WeakPolarHBondContact O-CB 3.1Å; V468-M472 PolarHBondContact O-N 2.73Å
469E88.2Confident76.3Confident119 Ų11981.2 Ų81.256%0.55643%0.427SS*.G310 helixtrans-58.2-25176.7-64.3178.1119.400113.2F417 S467 I471F417-E469 HydrophobicContact CE2-CG 4.03Å; F417-E469 HydrophobicContact CZ-CG 3.63Å; F417-E469 WeakPolarHBondContact CZ-OE1 3.25Å; S467-E469 PolarHBondContact O-N 3.11Å; S467-E469 PolarHBondContact OG-N 3.19Å; S467-E469 PolarHBondContact OG-OE2 3.37Å; E469-I471 PolarHBondContact O-N 3.12Å
470Q86.2Confident77.4Confident122 Ų12279.2 Ų79.257%0.5740%0.404SS*.G310 helixtrans-69.1-22.6179.9-64.4172.2-32.100113.1S467 V468S467-Q470 VanDerWaalsContact O-CB 3.32Å; S467-Q470 WeakPolarHBondContact O-CB 3.36Å; S467-Q470 WeakPolarHBondContact O-CG 3.3Å; S467-Q470 PolarHBondContact O-N 2.64Å; S467-Q470 PolarHBondContact O-OE1 3.32Å; V468-Q470 PolarHBondContact O-N 2.72Å; V468-Q470 VanDerWaalsContact O-N 3.11Å
471I87.4Confident78.6Confident24 Ų2473.6 Ų73.612%0.12338%0.378CS..THydrogen-bonded Turntrans-127.5-6.3-177.458.3170000114.1L424 V450 A454 L455 M458 F466 V468 E469L424-I471 HydrophobicContact CD1-CD1 4.27Å; V450-I471 HydrophobicContact CG1-CD1 3.67Å; V450-I471 HydrophobicContact CG1-CG1 4.19Å; V450-I471 HydrophobicContact CG2-CD1 4.41Å; V450-I471 HydrophobicContact CG2-CG1 4.26Å; A454-I471 HydrophobicContact CB-CB 4.24Å; L455-I471 HydrophobicContact CD2-CD1 3.73Å; L455-I471 HydrophobicContact CG-CD1 3.97Å; M458-I471 HydrophobicContact CG-CG2 3.53Å; M458-I471 HydrophobicContact SD-CB 4.43Å; M458-I471 HydrophobicContact SD-CD1 4.24Å; M458-I471 HydrophobicContact SD-CG2 3.18Å; M458-I471 WeakPolarHBondContact SD-CG2 3.36Å; F466-I471 HydrophobicContact CE2-CD1 3.75Å; F466-I471 HydrophobicContact CE2-CG1 4.05Å; F466-I471 HydrophobicContact CZ-CD1 3.76Å; F466-I471 HydrophobicContact CZ-CG1 4.12Å; V468-I471 WeakPolarHBondContact O-CG1 3.37Å; V468-I471 PolarHBondContact O-N 3.21Å; V468-I471 VanDerWaalsContact O-N 3.09Å; E469-I471 PolarHBondContact O-N 3.12Å
472M87.8Confident80Confident29 Ų2978.9 Ų78.914%0.14340%0.398CS..  trans-75.2131.1179.8-178.4-178.77600109.7V438 V447 G448 C449 V450 V468 P474V438-M472 HydrophobicContact CB-SD 3.62Å; V438-M472 HydrophobicContact CG1-SD 3.9Å; V438-M472 HydrophobicContact CG2-CG 4.17Å; V438-M472 HydrophobicContact CG2-SD 3.84Å; V447-M472 HydrophobicContact CG2-CE 4.24Å; V447-M472 HydrophobicContact CG2-SD 4Å; G448-M472 VanDerWaalsContact CA-SD 3.53Å; C449-M472 CarbonylContact O-C 3.52Å; C449-M472 WeakPolarHBondContact O-CA 3.24Å; V450-M472 HydrophobicContact CG2-CB 4.28Å; V468-M472 HydrophobicContact CG2-CB 4.44Å; V468-M472 WeakPolarHBondContact O-CB 3.1Å; V468-M472 PolarHBondContact O-N 2.73Å; M472-P474 WeakPolarHBondContact O-CD 3.22Å
473Q85.3Confident81.3Confident76 Ų7673.8 Ų73.836%0.35537%0.368SS..BIsolated β-bridgetrans-83.5116.2165.9-175.2177.4-14.500108.4G448 C449 H475G448-Q473 CarbonylContact C-O 3.52Å; G448-Q473 WeakPolarHBondContact CA-O 3.09Å; C449-Q473 PolarHBondContact N-O 3.12Å; C449-Q473 PolarHBondContact O-N 3.37Å; Q473-H475 VanDerWaalsContact C-N 3.35Å; Q473-H475 VanDerWaalsContact CG-O 3.24Å; Q473-H475 WeakPolarHBondContact CG-O 3.32Å; Q473-H475 PolarHBondContact NE2-O 3.23Å
474P81.3Confident82.8Confident75 Ų7566.8 Ų66.849%0.48734%0.341SS..SBendtrans-77.6-20.6-177.129.9-34.6000113.1M472M472-P474 WeakPolarHBondContact O-CD 3.22Å
475H80.1Confident84Confident153 Ų15360 Ų6071%0.70831%0.305SS*.  trans-118.6126.3-176.3-61.4-56.8000111.2Q473Q473-H475 VanDerWaalsContact C-N 3.35Å; Q473-H475 VanDerWaalsContact CG-O 3.24Å; Q473-H475 WeakPolarHBondContact CG-O 3.32Å; Q473-H475 PolarHBondContact NE2-O 3.23Å
476F82.5Confident84.3Confident40 Ų4054 Ų5418%0.17527%0.273CS..  trans-151.4154.6173.851.3-91.1000108.3F437 T446 C449 V478 F497 A499F437-F476 HydrophobicContact CD1-CE2 4.21Å; F437-F476 AromaticContact CD1-CZ 3.98Å; F437-F476 HydrophobicContact CD1-CZ 3.98Å; F437-F476 HydrophobicContact CE1-CD2 4.22Å; F437-F476 AromaticContact CE1-CE2 3.79Å; F437-F476 HydrophobicContact CE1-CE2 3.79Å; F437-F476 HydrophobicContact CE1-CZ 4.01Å; T446-F476 HydrophobicContact CG2-CE1 4.3Å; T446-F476 HydrophobicContact CG2-CZ 3.75Å; C449-F476 HydrophobicContact CB-CD1 4.25Å; C449-F476 HydrophobicContact CB-CE1 4.32Å; F476-V478 HydrophobicContact CD2-CG2 3.78Å; F476-V478 HydrophobicContact CE2-CG2 3.52Å; F476-V478 PolarHBondContact O-N 3.46Å; F476-F497 HydrophobicContact CB-CE1 4.42Å; F476-F497 HydrophobicContact CB-CE2 3.78Å; F476-F497 HydrophobicContact CB-CZ 3.43Å; F476-F497 VanDerWaalsContact CB-CZ 3.43Å; F476-F497 HydrophobicContact CD2-CE2 4.03Å; F476-F497 HydrophobicContact CD2-CZ 4.42Å; F476-F497 AromaticContact CG-CE2 3.99Å; F476-F497 HydrophobicContact CG-CE2 3.99Å; F476-F497 AromaticContact CG-CZ 3.91Å; F476-F497 HydrophobicContact CG-CZ 3.91Å; F476-A499 HydrophobicContact CD2-CB 3.65Å; F476-A499 HydrophobicContact CE2-CB 3.63Å
477E80.9Confident84.2Confident56 Ų5656.5 Ų56.526%0.26229%0.285SS..  trans-70.2130.4-178.7-70.5-67.1176.300110.7K379 M491 E495 A499K379-E477 IonicContact NZ-OE1 2.79Å; K379-E477 PolarHBondContact NZ-OE1 3.4Å; E477-M491 HydrophobicContact CB-CE 4.44Å; E477-M491 HydrophobicContact CG-CE 4.47Å; E477-E495 HydrophobicContact CG-CG 3.83Å; E477-A499 WeakPolarHBondContact O-CB 3.38Å; E477-A499 PolarHBondContact O-N 2.73Å
478V82.3Confident84Confident69 Ų6955 Ų5542%0.41827%0.274SS..EExtended strand (participates in β ladder)trans-120.6123.6175.9-174.90000109F476 A499F476-V478 HydrophobicContact CD2-CG2 3.78Å; F476-V478 HydrophobicContact CE2-CG2 3.52Å; F476-V478 PolarHBondContact O-N 3.46Å; V478-A499 CarbonylContact C-O 3.49Å; V478-A499 VanDerWaalsContact CA-O 3.23Å; V478-A499 WeakPolarHBondContact CA-O 3.36Å; V478-A499 HydrophobicContact CG2-CB 4Å
479V82.6Confident83.8Confident12 Ų1258.2 Ų58.27%0.07329%0.289CS..EExtended strand (participates in β ladder)trans-110.4152173.3-61.40000110.7C483 V488 M491 V498 A499 V500 G501V479-C483 HydrophobicContact CB-CB 3.86Å; V479-C483 HydrophobicContact CG2-CB 4.19Å; V479-V488 HydrophobicContact CB-CG2 4.46Å; V479-V488 HydrophobicContact CG1-CG2 4.3Å; V479-V488 HydrophobicContact CG2-CG2 3.8Å; V479-M491 HydrophobicContact CG1-CE 3.91Å; V479-M491 HydrophobicContact CG1-SD 3.41Å; V479-M491 WeakPolarHBondContact CG1-SD 3.44Å; V479-V498 HydrophobicContact CB-CG1 4.26Å; V479-V498 HydrophobicContact CG1-CG1 3.69Å; V479-V498 HydrophobicContact CG2-CG1 3.72Å; V479-A499 PolarHBondContact N-O 3.36Å; V479-V500 HydrophobicContact CG2-CB 4.46Å; V479-V500 HydrophobicContact CG2-CG1 4.49Å; V479-V500 HydrophobicContact CG2-CG2 4.05Å; V479-V500 CarbonylContact O-C 3.56Å; V479-V500 WeakPolarHBondContact O-CA 3.13Å; V479-G501 PolarHBondContact O-N 3.42Å
480D82.7Confident83.2Confident49 Ų4954.2 Ų54.226%0.26227%0.27SS..EExtended strand (participates in β ladder)trans-71.2148.7170.3-177.7-93.2000111K482 C483 G501 G503 G504D480-K482 PolarHBondContact O-N 3.06Å; D480-K482 WeakPolarHBondContact OD1-CA 3.44Å; D480-K482 WeakPolarHBondContact OD1-CB 3.43Å; D480-K482 WeakPolarHBondContact OD1-CG 3.29Å; D480-K482 PolarHBondContact OD1-N 3.48Å; D480-C483 WeakPolarHBondContact O-CB 3.37Å; D480-C483 PolarHBondContact O-N 2.64Å; D480-G501 WeakPolarHBondContact CA-O 3.28Å; D480-G503 WeakPolarHBondContact OD2-CA 3.39Å; D480-G503 PolarHBondContact OD2-N 2.8Å; D480-G503 VanDerWaalsContact OD2-N 3.14Å; D480-G504 PolarHBondContact OD2-N 3.42Å
481E82.7Confident82.8Confident39 Ų3950.6 Ų50.618%0.18225%0.254CS..THydrogen-bonded Turntrans-57.8-19.5177.871.8-176.8174.900114.1D405 V500 G501 K502D405-E481 HydrophobicContact CB-CB 4.22Å; D405-E481 WeakPolarHBondContact CB-O 3.45Å; D405-E481 PolarHBondContact N-O 2.94Å; E481-V500 HydrophobicContact CB-CG1 3.95Å; E481-G501 PolarHBondContact N-O 3.28Å; E481-G501 VanDerWaalsContact N-O 3.09Å; E481-K502 VanDerWaalsContact CD-CG 3.47Å; E481-K502 WeakPolarHBondContact OE2-CE 3.23Å; E481-K502 WeakPolarHBondContact OE2-CG 3.48Å
482K84.5Confident82.5Confident129 Ų12951.4 Ų51.456%0.56126%0.258SS*.THydrogen-bonded Turntrans-86-5.1173.9-42.3-140.5178.7152.50114R403 D480R403-K482 VanDerWaalsContact NE-CA 3.33Å; D480-K482 PolarHBondContact O-N 3.06Å; D480-K482 WeakPolarHBondContact OD1-CA 3.44Å; D480-K482 WeakPolarHBondContact OD1-CB 3.43Å; D480-K482 WeakPolarHBondContact OD1-CG 3.29Å; D480-K482 PolarHBondContact OD1-N 3.48Å
483C82.6Confident82.1Confident12 Ų1254.5 Ų54.58%0.08127%0.271CS..SBendtrans-55136.1177.6179.50000110.5R403 V404 V479 D480 Q487R403-C483 WeakPolarHBondContact CA-O 3.31Å; V404-C483 HydrophobicContact CG2-CB 4.22Å; V404-C483 VanDerWaalsContact CG2-O 3.24Å; V404-C483 WeakPolarHBondContact CG2-O 3.27Å; V404-C483 PolarHBondContact N-O 3.21Å; V479-C483 HydrophobicContact CB-CB 3.86Å; V479-C483 HydrophobicContact CG2-CB 4.19Å; D480-C483 WeakPolarHBondContact O-CB 3.37Å; D480-C483 PolarHBondContact O-N 2.64Å; C483-Q487 VanDerWaalsContact SG-CB 3.58Å; C483-Q487 PolarHBondContact SG-OE1 2.59Å
484P85.6Confident81.7Confident36 Ų3657.6 Ų57.623%0.23429%0.285CS..BIsolated β-bridgetrans-61.3137.6170.5-24.735.4000111.7K402 V486 Q487 V488K402-P484 CarbonylContact O-C 3.54Å; K402-P484 WeakPolarHBondContact O-CA 3.28Å; P484-V486 HydrophobicContact CB-CG1 4.03Å; P484-V486 PolarHBondContact O-N 3.28Å; P484-V486 VanDerWaalsContact O-N 3.07Å; P484-Q487 PolarHBondContact O-N 3.46Å; P484-V488 PolarHBondContact O-N 3.15Å
485I86.3Confident81.5Confident6 Ų657 Ų573%0.03128%0.276CS..Hα-helixtrans-58.3-28.1-179.4-63.2171.7000111.3W399 K402 V404 L407 Q487 V488 H489W399-I485 HydrophobicContact CE3-CB 4.16Å; W399-I485 HydrophobicContact CE3-CG2 3.61Å; W399-I485 HydrophobicContact CZ3-CB 4.42Å; W399-I485 HydrophobicContact CZ3-CG2 3.71Å; K402-I485 HydrophobicContact CB-CD1 3.73Å; K402-I485 HydrophobicContact CB-CG1 4.45Å; K402-I485 WeakPolarHBondContact O-CG1 3.4Å; K402-I485 PolarHBondContact O-N 3.14Å; V404-I485 HydrophobicContact CG2-CG1 4.33Å; L407-I485 HydrophobicContact CD1-CD1 4Å; L407-I485 HydrophobicContact CD1-CG1 4.09Å; L407-I485 HydrophobicContact CD1-CG2 4.5Å; L407-I485 HydrophobicContact CD2-CD1 3.83Å; L407-I485 HydrophobicContact CG-CD1 3.77Å; L407-I485 HydrophobicContact CG-CG1 4.34Å; I485-Q487 VanDerWaalsContact C-N 3.33Å; I485-Q487 PolarHBondContact O-N 2.81Å; I485-V488 PolarHBondContact O-N 3.2Å; I485-H489 WeakPolarHBondContact O-CB 3.32Å; I485-H489 PolarHBondContact O-N 2.94Å
486V82.7Confident81.5Confident11 Ų1156.7 Ų56.77%0.06728%0.275CS..Hα-helixtrans-61-39.7175.167.50000113.2P391 Q400 P484 V488 H489 E490P391-V486 HydrophobicContact CB-CG2 3.89Å; P391-V486 HydrophobicContact CG-CG1 4.18Å; P391-V486 HydrophobicContact CG-CG2 4.08Å; Q400-V486 HydrophobicContact CB-CB 3.76Å; Q400-V486 HydrophobicContact CB-CG1 4.4Å; Q400-V486 HydrophobicContact CB-CG2 4.23Å; Q400-V486 HydrophobicContact CG-CB 4.06Å; Q400-V486 HydrophobicContact CG-CG2 4.08Å; Q400-V486 WeakPolarHBondContact O-CB 3.33Å; Q400-V486 VanDerWaalsContact O-CG1 3.27Å; Q400-V486 WeakPolarHBondContact O-CG1 3.5Å; Q400-V486 PolarHBondContact O-N 3.36Å; Q400-V486 VanDerWaalsContact O-N 3.07Å; P484-V486 HydrophobicContact CB-CG1 4.03Å; P484-V486 PolarHBondContact O-N 3.28Å; P484-V486 VanDerWaalsContact O-N 3.07Å; V486-V488 VanDerWaalsContact C-N 3.35Å; V486-H489 PolarHBondContact O-N 2.94Å; V486-E490 HydrophobicContact CG2-CG 4.46Å; V486-E490 WeakPolarHBondContact O-CG 3.44Å; V486-E490 PolarHBondContact O-N 3.32Å
487Q80.7Confident81.5Confident90 Ų9055.5 Ų55.542%0.42127%0.269SS..Hα-helixtrans-66.3-42.4178.2-74.3-178.7-17.600110.2C483 P484 I485 H489 E490 M491C483-Q487 VanDerWaalsContact SG-CB 3.58Å; C483-Q487 PolarHBondContact SG-OE1 2.59Å; P484-Q487 PolarHBondContact O-N 3.46Å; I485-Q487 VanDerWaalsContact C-N 3.33Å; I485-Q487 PolarHBondContact O-N 2.81Å; Q487-H489 VanDerWaalsContact C-N 3.33Å; Q487-H489 PolarHBondContact O-N 3.03Å; Q487-E490 PolarHBondContact O-N 3.46Å; Q487-M491 WeakPolarHBondContact O-CG 3.22Å; Q487-M491 PolarHBondContact O-N 3.42Å
488V83.8Confident81.7Confident7 Ų753.1 Ų53.14%0.04226%0.259CS..Hα-helixtrans-62.8-40.6173.8-178.50000111.8V404 V479 P484 I485 V486 M491 L492 V498V404-V488 HydrophobicContact CG2-CB 4.3Å; V404-V488 HydrophobicContact CG2-CG2 3.34Å; V479-V488 HydrophobicContact CB-CG2 4.46Å; V479-V488 HydrophobicContact CG1-CG2 4.3Å; V479-V488 HydrophobicContact CG2-CG2 3.8Å; P484-V488 PolarHBondContact O-N 3.15Å; I485-V488 PolarHBondContact O-N 3.2Å; V486-V488 VanDerWaalsContact C-N 3.35Å; V488-M491 WeakPolarHBondContact O-CB 3.23Å; V488-M491 PolarHBondContact O-N 3.48Å; V488-L492 HydrophobicContact CG1-CD1 3.88Å; V488-L492 HydrophobicContact CG1-CG 4.24Å; V488-L492 WeakPolarHBondContact O-CB 3.36Å; V488-L492 VanDerWaalsContact O-CG 3.25Å; V488-L492 WeakPolarHBondContact O-CG 3.29Å; V488-L492 PolarHBondContact O-N 2.75Å; V488-V498 HydrophobicContact CG1-CB 4.08Å; V488-V498 HydrophobicContact CG1-CG1 4.32Å; V488-V498 HydrophobicContact CG1-CG2 4.26Å
489H83.3Confident81.8Confident68 Ų6849.9 Ų49.932%0.31524%0.239SC..Hα-helixtrans-63.5-42.9177.1174.774.3000112.2W399 I485 V486 Q487 L492 K493W399-H489 HydrophobicContact CH2-CB 3.82Å; W399-H489 AromaticContact CH2-CD2 3.86Å; W399-H489 AromaticContact CH2-CG 3.63Å; W399-H489 HydrophobicContact CZ3-CB 3.88Å; I485-H489 WeakPolarHBondContact O-CB 3.32Å; I485-H489 PolarHBondContact O-N 2.94Å; V486-H489 PolarHBondContact O-N 2.94Å; Q487-H489 VanDerWaalsContact C-N 3.33Å; Q487-H489 PolarHBondContact O-N 3.03Å; H489-L492 PolarHBondContact O-N 2.67Å; H489-K493 WeakPolarHBondContact NE2-CE 3.29Å; H489-K493 PolarHBondContact O-N 3.17Å
490E75.5Confident81.7Confident36 Ų3649.7 Ų49.717%0.16824%0.238CC..Hα-helixtrans-64.3-41175.6-67.2-60.8153.200111.2T392 V486 Q487 L492 K493T392-E490 PolarHBondContact OG1-OE1 3.35Å; V486-E490 HydrophobicContact CG2-CG 4.46Å; V486-E490 WeakPolarHBondContact O-CG 3.44Å; V486-E490 PolarHBondContact O-N 3.32Å; Q487-E490 PolarHBondContact O-N 3.46Å; E490-L492 PolarHBondContact O-N 2.78Å; E490-K493 WeakPolarHBondContact O-CB 3.43Å; E490-K493 PolarHBondContact O-N 2.97Å; E490-K493 IonicContact OE1-NZ 3.82Å; E490-K493 PolarHBondContact OE1-NZ 2.85Å; E490-K493 WeakPolarHBondContact OE2-CD 3.39Å; E490-K493 WeakPolarHBondContact OE2-CE 3.4Å; E490-K493 IonicContact OE2-NZ 3.2Å; E490-K493 PolarHBondContact OE2-NZ 2.87Å
491M78.7Confident81.3Confident45 Ų4547.8 Ų47.822%0.22223%0.23CC..Hα-helixtrans-59.4-46.2172.3-72.9173149.600111.8E477 V479 Q487 V488 K493 H494 E495 V498E477-M491 HydrophobicContact CB-CE 4.44Å; E477-M491 HydrophobicContact CG-CE 4.47Å; V479-M491 HydrophobicContact CG1-CE 3.91Å; V479-M491 HydrophobicContact CG1-SD 3.41Å; V479-M491 WeakPolarHBondContact CG1-SD 3.44Å; Q487-M491 WeakPolarHBondContact O-CG 3.22Å; Q487-M491 PolarHBondContact O-N 3.42Å; V488-M491 WeakPolarHBondContact O-CB 3.23Å; V488-M491 PolarHBondContact O-N 3.48Å; M491-K493 PolarHBondContact O-N 3.39Å; M491-K493 VanDerWaalsContact O-N 3.1Å; M491-H494 PolarHBondContact O-N 3.01Å; M491-E495 WeakPolarHBondContact O-CB 3.29Å; M491-E495 PolarHBondContact O-N 2.89Å; M491-V498 HydrophobicContact CB-CG2 3.63Å; M491-V498 HydrophobicContact SD-CG1 4.2Å; M491-V498 HydrophobicContact SD-CG2 4.3Å
492L81.2Confident80.6Confident42 Ų4250.7 Ų50.722%0.2224%0.242CC..THydrogen-bonded Turntrans-66.3-9179.5-72.4172.1000114.4V488 H489 E490 H494 E495 V498 F515V488-L492 HydrophobicContact CG1-CD1 3.88Å; V488-L492 HydrophobicContact CG1-CG 4.24Å; V488-L492 WeakPolarHBondContact O-CB 3.36Å; V488-L492 VanDerWaalsContact O-CG 3.25Å; V488-L492 WeakPolarHBondContact O-CG 3.29Å; V488-L492 PolarHBondContact O-N 2.75Å; H489-L492 PolarHBondContact O-N 2.67Å; E490-L492 PolarHBondContact O-N 2.78Å; L492-H494 PolarHBondContact O-N 3.28Å; L492-E495 WeakPolarHBondContact CA-O 2.82Å; L492-V498 HydrophobicContact CD2-CB 4.47Å; L492-V498 HydrophobicContact CD2-CG2 3.89Å; L492-V498 HydrophobicContact CG-CG2 3.98Å; L492-F515 HydrophobicContact CD1-CD2 4.01Å
493K78.7Confident79.4Confident94 Ų9447.1 Ų47.141%0.40924%0.242SC..THydrogen-bonded Turntrans-73-17.6169.1-67.6177.1-172.4169.70112.6H489 E490 M491H489-K493 WeakPolarHBondContact NE2-CE 3.29Å; H489-K493 PolarHBondContact O-N 3.17Å; E490-K493 WeakPolarHBondContact O-CB 3.43Å; E490-K493 PolarHBondContact O-N 2.97Å; E490-K493 IonicContact OE1-NZ 3.82Å; E490-K493 PolarHBondContact OE1-NZ 2.85Å; E490-K493 WeakPolarHBondContact OE2-CD 3.39Å; E490-K493 WeakPolarHBondContact OE2-CE 3.4Å; E490-K493 IonicContact OE2-NZ 3.2Å; E490-K493 PolarHBondContact OE2-NZ 2.87Å; M491-K493 PolarHBondContact O-N 3.39Å; M491-K493 VanDerWaalsContact O-N 3.1Å
494H77.3Confident77.6Confident141 Ų14149.3 Ų49.365%0.65327%0.266SS*.THydrogen-bonded Turntrans-125.9-26.4-174.7-59.3-53.4000112.8M491 L492M491-H494 PolarHBondContact O-N 3.01Å; L492-H494 PolarHBondContact O-N 3.28Å
495E77.5Confident75.3Confident61 Ų6152.5 Ų52.529%0.28529%0.285SS..  trans-105.8141.8178.1-56-59.4148.500110.9E477 M491 L492 F497E477-E495 HydrophobicContact CG-CG 3.83Å; M491-E495 WeakPolarHBondContact O-CB 3.29Å; M491-E495 PolarHBondContact O-N 2.89Å; L492-E495 WeakPolarHBondContact CA-O 2.82Å; E495-F497 VanDerWaalsContact C-N 3.26Å; E495-F497 PolarHBondContact O-N 3.18Å
496E79.4Confident73.4Confident147 Ų14758.3 Ų58.369%0.68731%0.312SS*.SBendtrans-68.8-26.7177-70.6-174.5159.900112.8L451L451-E496 WeakPolarHBondContact CD1-OE2 3.16Å
497F82.9Confident71.2Confident15 Ų1560.3 Ų60.37%0.06633%0.33CS..  trans-153.6161.1175.871.7-81.8000110.4P435 F437 C449 L451 F476 E495P435-F497 HydrophobicContact CB-CE1 4.44Å; P435-F497 HydrophobicContact CB-CE2 4.4Å; P435-F497 HydrophobicContact CB-CZ 4.35Å; P435-F497 HydrophobicContact CG-CB 4.1Å; P435-F497 HydrophobicContact CG-CD1 3.56Å; P435-F497 HydrophobicContact CG-CD2 3.68Å; P435-F497 HydrophobicContact CG-CE1 3.88Å; P435-F497 HydrophobicContact CG-CE2 3.97Å; P435-F497 HydrophobicContact CG-CG 3.47Å; P435-F497 VanDerWaalsContact CG-CG 3.47Å; P435-F497 HydrophobicContact CG-CZ 4.07Å; F437-F497 HydrophobicContact CE1-CE2 4.06Å; F437-F497 HydrophobicContact CZ-CD2 4.42Å; F437-F497 HydrophobicContact CZ-CE2 4.09Å; C449-F497 HydrophobicContact CB-CZ 4.36Å; C449-F497 WeakPolarHBondContact SG-CZ 2.9Å; L451-F497 HydrophobicContact CD2-CD1 3.83Å; L451-F497 HydrophobicContact CD2-CE1 3.7Å; L451-F497 HydrophobicContact CG-CE1 4.42Å; F476-F497 HydrophobicContact CB-CE1 4.42Å; F476-F497 HydrophobicContact CB-CE2 3.78Å; F476-F497 HydrophobicContact CB-CZ 3.43Å; F476-F497 VanDerWaalsContact CB-CZ 3.43Å; F476-F497 HydrophobicContact CD2-CE2 4.03Å; F476-F497 HydrophobicContact CD2-CZ 4.42Å; F476-F497 AromaticContact CG-CE2 3.99Å; F476-F497 HydrophobicContact CG-CE2 3.99Å; F476-F497 AromaticContact CG-CZ 3.91Å; F476-F497 HydrophobicContact CG-CZ 3.91Å; E495-F497 VanDerWaalsContact C-N 3.26Å; E495-F497 PolarHBondContact O-N 3.18Å
498V84.1Confident68.9Low7 Ų757.9 Ų57.94%0.04233%0.325CS..  trans-126.6128.5170177.60000107.8V479 V488 M491 L492V479-V498 HydrophobicContact CB-CG1 4.26Å; V479-V498 HydrophobicContact CG1-CG1 3.69Å; V479-V498 HydrophobicContact CG2-CG1 3.72Å; V488-V498 HydrophobicContact CG1-CB 4.08Å; V488-V498 HydrophobicContact CG1-CG1 4.32Å; V488-V498 HydrophobicContact CG1-CG2 4.26Å; M491-V498 HydrophobicContact CB-CG2 3.63Å; M491-V498 HydrophobicContact SD-CG1 4.2Å; M491-V498 HydrophobicContact SD-CG2 4.3Å; L492-V498 HydrophobicContact CD2-CB 4.47Å; L492-V498 HydrophobicContact CD2-CG2 3.89Å; L492-V498 HydrophobicContact CG-CG2 3.98Å
499A84.5Confident66.5Low1 Ų159.9 Ų59.91%0.00834%0.337CS..EExtended strand (participates in β ladder)trans-81.9135.3175.500000110F437 F476 E477 V478 V479 T510F437-A499 HydrophobicContact CE1-CB 4.04Å; F437-A499 HydrophobicContact CZ-CB 4.09Å; F476-A499 HydrophobicContact CD2-CB 3.65Å; F476-A499 HydrophobicContact CE2-CB 3.63Å; E477-A499 WeakPolarHBondContact O-CB 3.38Å; E477-A499 PolarHBondContact O-N 2.73Å; V478-A499 CarbonylContact C-O 3.49Å; V478-A499 VanDerWaalsContact CA-O 3.23Å; V478-A499 WeakPolarHBondContact CA-O 3.36Å; V478-A499 HydrophobicContact CG2-CB 4Å; V479-A499 PolarHBondContact N-O 3.36Å; A499-T510 HydrophobicContact CB-CG2 3.34Å
500V81.3Confident64.5Low7 Ų757.1 Ų57.14%0.04233%0.325CS..EExtended strand (participates in β ladder)trans-106115.8178-174.90000109.7V404 V479 E481 T509 T510 F511V404-V500 HydrophobicContact CG1-CB 4.25Å; V404-V500 HydrophobicContact CG1-CG1 3.73Å; V404-V500 HydrophobicContact CG1-CG2 3.48Å; V404-V500 VanDerWaalsContact CG1-CG2 3.48Å; V479-V500 HydrophobicContact CG2-CB 4.46Å; V479-V500 HydrophobicContact CG2-CG1 4.49Å; V479-V500 HydrophobicContact CG2-CG2 4.05Å; V479-V500 CarbonylContact O-C 3.56Å; V479-V500 WeakPolarHBondContact O-CA 3.13Å; E481-V500 HydrophobicContact CB-CG1 3.95Å; V500-T509 CarbonylContact O-C 3.58Å; V500-T510 WeakPolarHBondContact O-CA 3.3Å; V500-F511 HydrophobicContact CB-CB 3.97Å; V500-F511 HydrophobicContact CB-CD2 4.37Å; V500-F511 HydrophobicContact CG1-CD2 4.4Å; V500-F511 HydrophobicContact CG2-CB 4.15Å; V500-F511 PolarHBondContact N-O 2.87Å; V500-F511 PolarHBondContact O-N 3.01Å
501G74.3Confident63Low10 Ų1057.9 Ų57.910%0.10333%0.328CS..EExtended strand (participates in β ladder)trans-100.3147.1178.800000113.4V479 D480 E481V479-G501 PolarHBondContact O-N 3.42Å; D480-G501 WeakPolarHBondContact CA-O 3.28Å; E481-G501 PolarHBondContact N-O 3.28Å; E481-G501 VanDerWaalsContact N-O 3.09Å
502K68.6Low61Low100 Ų10056.1 Ų56.144%0.43532%0.32SS..G310 helixtrans-81.1117168.4-99.4-176177.6178.50110.6E481E481-K502 VanDerWaalsContact CD-CG 3.47Å; E481-K502 WeakPolarHBondContact OE2-CE 3.23Å; E481-K502 WeakPolarHBondContact OE2-CG 3.48Å
503G58.6Low58.7Low54 Ų5455.4 Ų55.456%0.55732%0.319SS*.G310 helixtrans7729.7171.500000114.5D480 V505D480-G503 WeakPolarHBondContact OD2-CA 3.39Å; D480-G503 PolarHBondContact OD2-N 2.8Å; D480-G503 VanDerWaalsContact OD2-N 3.14Å; G503-V505 PolarHBondContact O-N 3.18Å
504G44.9Very low56.6Low57 Ų5754.3 Ų54.359%0.58832%0.322SS*.G310 helixtrans60.6-2174.800000116.8D480D480-G504 PolarHBondContact OD2-N 3.42Å
505V38.1Very low54.4Low103 Ų10353.3 Ų53.362%0.62432%0.316SS*.SBendtrans-132.7107.1-172.3-179.30000107.8G503 A507G503-V505 PolarHBondContact O-N 3.18Å; V505-A507 WeakPolarHBondContact O-CB 3.31Å; V505-A507 PolarHBondContact O-N 3.47Å
506H45.4Very low52.1Low129 Ų12958.9 Ų58.960%0.59734%0.34SS*.SBendtrans26.813.1155.6-70.3-66.1000121.5R445 A508R445-H506 HydrophobicContact CB-CB 4.32Å; H506-A508 PolarHBondContact O-N 2.86Å
507A35.5Very low49.6Very low53 Ų5366.2 Ų66.244%0.43836%0.363SS..  trans-87.896.9175.500000105.8V505 T509V505-A507 WeakPolarHBondContact O-CB 3.31Å; V505-A507 PolarHBondContact O-N 3.47Å; A507-T509 VanDerWaalsContact C-N 3.31Å; A507-T509 PolarHBondContact O-N 3.48Å
508A32.5Very low48Very low38 Ų3868.8 Ų68.831%0.31438%0.378SS..SBendtrans-46.586.1178.100000112.8F414 L439 H506F414-A508 HydrophobicContact CE1-CB 3.67Å; F414-A508 HydrophobicContact CE2-CB 4.15Å; F414-A508 HydrophobicContact CZ-CB 3.43Å; F414-A508 VanDerWaalsContact CZ-CB 3.43Å; L439-A508 HydrophobicContact CD2-CB 4.45Å; H506-A508 PolarHBondContact O-N 2.86Å
509T35.2Very low46.1Very low50 Ų5072.1 Ų72.131%0.30740%0.396SS..  trans-130.164.5151.4-5.80000106.1V500 A507 F511V500-T509 CarbonylContact O-C 3.58Å; A507-T509 VanDerWaalsContact C-N 3.31Å; A507-T509 PolarHBondContact O-N 3.48Å; T509-F511 HydrophobicContact CG2-CE2 4.25Å; T509-F511 HydrophobicContact CG2-CZ 4.24Å; T509-F511 WeakPolarHBondContact O-CD2 3.26Å; T509-F511 WeakPolarHBondContact O-CE2 3.46Å; T509-F511 PolarHBondContact O-N 2.92Å
510T41.3Very low43.9Very low9 Ų976 Ų766%0.05542%0.417CS..  trans-76.197.7-171.5-36.20000112.2P412 F437 A499 V500P412-T510 WeakPolarHBondContact CB-O 3.13Å; P412-T510 WeakPolarHBondContact CD-O 3.34Å; P412-T510 WeakPolarHBondContact CG-O 3.35Å; F437-T510 HydrophobicContact CD1-CG2 4.23Å; F437-T510 HydrophobicContact CD2-CG2 4.06Å; F437-T510 HydrophobicContact CE1-CG2 3.7Å; F437-T510 HydrophobicContact CE2-CG2 3.51Å; F437-T510 HydrophobicContact CG-CG2 4.39Å; F437-T510 HydrophobicContact CZ-CG2 3.31Å; A499-T510 HydrophobicContact CB-CG2 3.34Å; V500-T510 WeakPolarHBondContact O-CA 3.3Å
511F42.8Very low41.7Very low53 Ų5380.1 Ų80.123%0.23244%0.439CS..BIsolated β-bridgetrans-81.3145.8176.1-62.1-83.1000112V409 V500 T509V409-F511 HydrophobicContact CB-CB 3.83Å; V409-F511 HydrophobicContact CB-CD1 3.99Å; V409-F511 HydrophobicContact CB-CG 4.31Å; V409-F511 HydrophobicContact CG2-CB 3.44Å; V409-F511 VanDerWaalsContact CG2-CB 3.44Å; V409-F511 HydrophobicContact CG2-CD1 3.46Å; V409-F511 VanDerWaalsContact CG2-CD1 3.46Å; V409-F511 HydrophobicContact CG2-CE1 4.37Å; V409-F511 HydrophobicContact CG2-CG 3.62Å; V500-F511 HydrophobicContact CB-CB 3.97Å; V500-F511 HydrophobicContact CB-CD2 4.37Å; V500-F511 HydrophobicContact CG1-CD2 4.4Å; V500-F511 HydrophobicContact CG2-CB 4.15Å; V500-F511 PolarHBondContact N-O 2.87Å; V500-F511 PolarHBondContact O-N 3.01Å; T509-F511 HydrophobicContact CG2-CE2 4.25Å; T509-F511 HydrophobicContact CG2-CZ 4.24Å; T509-F511 WeakPolarHBondContact O-CD2 3.26Å; T509-F511 WeakPolarHBondContact O-CE2 3.46Å; T509-F511 PolarHBondContact O-N 2.92Å
512V36.7Very low39.7Very low8 Ų884.4 Ų84.45%0.04846%0.46CS..  trans-125.2112.9174.5-177.80000108.8V409 K434 F437 P514V409-V512 WeakPolarHBondContact CG1-O 3.28Å; K434-V512 HydrophobicContact CB-CB 4.47Å; K434-V512 HydrophobicContact CB-CG1 4.17Å; K434-V512 HydrophobicContact CD-CB 3.98Å; K434-V512 HydrophobicContact CD-CG1 4.07Å; K434-V512 HydrophobicContact CG-CB 4.31Å; K434-V512 HydrophobicContact CG-CG1 3.91Å; K434-V512 PolarHBondContact NZ-O 3.39Å; K434-V512 VanDerWaalsContact NZ-O 3.07Å; F437-V512 HydrophobicContact CE2-CG2 3.88Å; F437-V512 HydrophobicContact CZ-CG2 4.2Å; V512-P514 WeakPolarHBondContact O-CD 3.29Å
513A33.4Very low37.8Very low26 Ų2683.4 Ų83.422%0.21546%0.462CS..  trans-89.1114.217000000109.5L407 V409 F515L407-A513 HydrophobicContact CD1-CB 4.4Å; V409-A513 VanDerWaalsContact CG1-CA 3.43Å; V409-A513 HydrophobicContact CG1-CB 3.56Å; A513-F515 HydrophobicContact CB-CD2 4.11Å; A513-F515 HydrophobicContact CB-CE2 4.08Å; A513-F515 PolarHBondContact O-N 2.98Å
514P34.9Very low36.3Very low72 Ų7285.5 Ų85.547%0.46846%0.455SS..  trans-76.4101.5164.929.7-26000107.6V512 F516V512-P514 WeakPolarHBondContact O-CD 3.29Å; P514-F516 HydrophobicContact CB-CD2 3.86Å; P514-F516 HydrophobicContact CB-CE2 3.74Å; P514-F516 PolarHBondContact O-N 3.28Å
515F31.1Very low35.6Very low120 Ų12087.7 Ų87.753%0.52645%0.445SS..  trans-87.891157.9-81.6-80.9000107.1L407 L492 A513L407-F515 HydrophobicContact CD1-CE2 4.17Å; L407-F515 HydrophobicContact CD1-CZ 4.45Å; L407-F515 HydrophobicContact CD2-CZ 4.43Å; L492-F515 HydrophobicContact CD1-CD2 4.01Å; A513-F515 HydrophobicContact CB-CD2 4.11Å; A513-F515 HydrophobicContact CB-CE2 4.08Å; A513-F515 PolarHBondContact O-N 2.98Å
516F28.8Very low35.4Very low178 Ų17886.4 Ų86.478%0.78143%0.43SS*.  trans-79.8135.6158-72.1-79.6000107.6P514P514-F516 HydrophobicContact CB-CD2 3.86Å; P514-F516 HydrophobicContact CB-CE2 3.74Å; P514-F516 PolarHBondContact O-N 3.28Å
517Y27.3Very low34.5Very low301 Ų30182.5 Ų82.5100%1.1842%0.415SS*.  trans-46.20171.4-89.2-88.7000113.6

Retrieved 517 of 517 residues in 1193.6 ms (Link to these results)