A0A077Z4K4_TRITR Loading...

glucuronosyltransferase

AlphaFold DB , UniProt , Accession A0A077Z4K4, Species TRITR (Trichuris trichiura, Whipworm), Gene n/a, Length 764 aa.

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Site Residue pLDDT pLDDT confidence pLDDT10 pLDDT10 confidence SASA SASA [Ų] SASA10 SASA10 [Ų] RSA RSA unformatted RSA10 RSA10 unformatted Surface Surface10 (not used) Disorder (not used) Disorder Sec. str. Secondary structure Isomer Phi (φ) Psi (ψ) Omega (ω) Chi 1 (χ1) Chi 2 (χ2) Chi 3 (χ3) Chi 4 (χ4) Chi 5 (χ5) Tau (τ) Contacts (colored by PAE) Contact details
1M43.6Very low49.1Very low223 Ų223119.8 Ų119.8100%1.09963%0.625SS**  0-31.60-74.8-177.1-171.400113.7N3 Y4M1-N3 PolarHBondContact O-N 3.28Å; M1-Y4 PolarHBondContact O-N 2.92Å
2I49.9Very low48.6Very low136 Ų136114 Ų11470%0.69761%0.607SS**G310 helixtrans-64.9-30.2-174.1-65.1169.5000114.2Y4 A5I2-Y4 VanDerWaalsContact C-N 3.29Å; I2-Y4 PolarHBondContact O-N 3.21Å; I2-A5 PolarHBondContact O-N 3.3Å
3N47.7Very low47.8Very low140 Ų140111.2 Ų111.275%0.74960%0.597SS**G310 helixtrans-72.4-12.1-176.8-70.7-5.6000115.6M1M1-N3 PolarHBondContact O-N 3.28Å
4Y52.4Low46.7Very low191 Ų191112.6 Ų112.675%0.74960%0.603SS**G310 helixtrans-98.3-12.4176.3-70.2-77.3000113.6M1 I2M1-Y4 PolarHBondContact O-N 2.92Å; I2-Y4 VanDerWaalsContact C-N 3.29Å; I2-Y4 PolarHBondContact O-N 3.21Å
5A50.8Low46Very low49 Ų49110.9 Ų110.941%0.40560%0.604SS.*Hα-helixtrans-76.5-34.7-17800000112.8I2 M8 I9I2-A5 PolarHBondContact O-N 3.3Å; A5-M8 PolarHBondContact O-N 3.4Å; A5-I9 WeakPolarHBondContact O-CG1 3.49Å; A5-I9 PolarHBondContact O-N 3.32Å; A5-I9 VanDerWaalsContact O-N 3.08Å
6I54.2Low45.2Very low120 Ų120112.4 Ų112.462%0.61561%0.609SS**Hα-helixtrans-65.2-48.5-176.1-60.9174.7000112.7M8 I9 A10I6-M8 VanDerWaalsContact C-N 3.32Å; I6-M8 PolarHBondContact O-N 3.44Å; I6-I9 PolarHBondContact O-N 3.22Å; I6-A10 PolarHBondContact O-N 2.81Å; I6-A10 VanDerWaalsContact O-N 3.09Å
7P44.9Very low44.3Very low65 Ų65114.1 Ų114.142%0.42261%0.612SS.*Hα-helixtrans-67.9-30.6177.622.1-29.8000113A10 I11P7-A10 PolarHBondContact O-N 3.13Å; P7-I11 VanDerWaalsContact O-CG1 3.28Å; P7-I11 WeakPolarHBondContact O-CG1 3.46Å; P7-I11 PolarHBondContact O-N 3.11Å
8M47.5Very low43.4Very low130 Ų130111.5 Ų111.564%0.6462%0.616SS**Hα-helixtrans-68.7-37.9176.4-80.5-70-75.100112.5A5 I6 I11 A12A5-M8 PolarHBondContact O-N 3.4Å; I6-M8 VanDerWaalsContact C-N 3.32Å; I6-M8 PolarHBondContact O-N 3.44Å; M8-I11 PolarHBondContact O-N 2.88Å; M8-A12 VanDerWaalsContact O-CB 3.32Å; M8-A12 WeakPolarHBondContact O-CB 3.29Å; M8-A12 PolarHBondContact O-N 3.01Å
9I54.7Low43Very low113 Ų113114.3 Ų114.358%0.57963%0.626SS**Hα-helixtrans-68.2-37173.7-66168.8000110.6A5 I6 A12 T13A5-I9 WeakPolarHBondContact O-CG1 3.49Å; A5-I9 PolarHBondContact O-N 3.32Å; A5-I9 VanDerWaalsContact O-N 3.08Å; I6-I9 PolarHBondContact O-N 3.22Å; I9-A12 PolarHBondContact O-N 3.42Å; I9-T13 WeakPolarHBondContact O-CB 3.47Å; I9-T13 PolarHBondContact O-N 2.87Å; I9-T13 PolarHBondContact O-OG1 3.3Å
10A46.2Very low42.9Very low45 Ų45118 Ų11837%0.37264%0.636SS.*Hα-helixtrans-65.4-40175.100000112.4I6 P7 T13 L14I6-A10 PolarHBondContact O-N 2.81Å; I6-A10 VanDerWaalsContact O-N 3.09Å; P7-A10 PolarHBondContact O-N 3.13Å; A10-T13 WeakPolarHBondContact CA-OG1 3.31Å; A10-T13 PolarHBondContact O-OG1 3.25Å; A10-T13 VanDerWaalsContact O-OG1 3.11Å; A10-L14 WeakPolarHBondContact O-CB 3.37Å; A10-L14 WeakPolarHBondContact O-CD1 3.21Å; A10-L14 VanDerWaalsContact O-CG 3.28Å; A10-L14 WeakPolarHBondContact O-CG 3.38Å; A10-L14 PolarHBondContact O-N 3.38Å
11I48.3Very low42.8Very low106 Ų106118.4 Ų118.454%0.54464%0.643SS.*Hα-helixtrans-72-38.3177.3-66.8166.7000111P7 M8 L14 S15P7-I11 VanDerWaalsContact O-CG1 3.28Å; P7-I11 WeakPolarHBondContact O-CG1 3.46Å; P7-I11 PolarHBondContact O-N 3.11Å; M8-I11 PolarHBondContact O-N 2.88Å; I11-L14 PolarHBondContact O-N 2.92Å; I11-S15 PolarHBondContact O-N 3.06Å; I11-S15 PolarHBondContact O-OG 3.41Å
12A43.1Very low43.3Very low50 Ų50110.5 Ų110.541%0.41361%0.613SS.*Hα-helixtrans-66.5-36.2174.900000112.5M8 I9 S15 I16M8-A12 VanDerWaalsContact O-CB 3.32Å; M8-A12 WeakPolarHBondContact O-CB 3.29Å; M8-A12 PolarHBondContact O-N 3.01Å; I9-A12 PolarHBondContact O-N 3.42Å; A12-S15 PolarHBondContact O-OG 3.12Å; A12-I16 WeakPolarHBondContact O-CG1 3.28Å; A12-I16 PolarHBondContact O-N 3.47Å
13T37.7Very low44.2Very low78 Ų78112.7 Ų112.748%0.47962%0.618SS.*Hα-helixtrans-74.1-31.8174.839.60000112.7I9 A10 H17I9-T13 WeakPolarHBondContact O-CB 3.47Å; I9-T13 PolarHBondContact O-N 2.87Å; I9-T13 PolarHBondContact O-OG1 3.3Å; A10-T13 WeakPolarHBondContact CA-OG1 3.31Å; A10-T13 PolarHBondContact O-OG1 3.25Å; A10-T13 VanDerWaalsContact O-OG1 3.11Å; T13-H17 PolarHBondContact O-N 3.39Å; T13-H17 PolarHBondContact O-ND1 3.13Å
14L32.3Very low45.8Very low130 Ų130108.9 Ų108.968%0.68161%0.605SS**Hα-helixtrans-74.1-30.7174.7-77.8164.7000113.3A10 I11 H17A10-L14 WeakPolarHBondContact O-CB 3.37Å; A10-L14 WeakPolarHBondContact O-CD1 3.21Å; A10-L14 VanDerWaalsContact O-CG 3.28Å; A10-L14 WeakPolarHBondContact O-CG 3.38Å; A10-L14 PolarHBondContact O-N 3.38Å; I11-L14 PolarHBondContact O-N 2.92Å; L14-H17 PolarHBondContact O-N 2.69Å
15S36.2Very low47.6Very low88 Ų88102.5 Ų102.562%0.61558%0.581SS**Hα-helixtrans-78.9-17.7177.336.90000113.7I11 A12I11-S15 PolarHBondContact O-N 3.06Å; I11-S15 PolarHBondContact O-OG 3.41Å; A12-S15 PolarHBondContact O-OG 3.12Å
16I33Very low49.5Very low134 Ų134104.1 Ų104.169%0.68758%0.58SS**Hα-helixtrans-85.4-21.6171-62.6170.8000111.8A12 G18A12-I16 WeakPolarHBondContact O-CG1 3.28Å; A12-I16 PolarHBondContact O-N 3.47Å; I16-G18 VanDerWaalsContact C-N 3.3Å; I16-G18 PolarHBondContact O-N 2.93Å
17H30.1Very low51.4Low142 Ų14298.4 Ų98.466%0.65755%0.551SS**THydrogen-bonded Turntrans-83.68.6179.5-93.774.5000115.5T13 L14 M19T13-H17 PolarHBondContact O-N 3.39Å; T13-H17 PolarHBondContact O-ND1 3.13Å; L14-H17 PolarHBondContact O-N 2.69Å; H17-M19 VanDerWaalsContact C-N 3.3Å; H17-M19 PolarHBondContact O-N 3.09Å
18G28.3Very low53.6Low67 Ų6795.3 Ų95.369%0.69153%0.531SS*.THydrogen-bonded Turntrans-73.7-15.5175.400000114.8I16 K20I16-G18 VanDerWaalsContact C-N 3.3Å; I16-G18 PolarHBondContact O-N 2.93Å; G18-K20 PolarHBondContact O-N 3.35Å; G18-K20 VanDerWaalsContact O-N 3.14Å
19M36.4Very low55.7Low164 Ų16489.1 Ų89.181%0.80850%0.5SS*.SBendtrans-78.596.9165.3-67.4-176.375.700107.1H17 T21H17-M19 VanDerWaalsContact C-N 3.3Å; H17-M19 PolarHBondContact O-N 3.09Å; M19-T21 PolarHBondContact O-N 2.9Å
20K40.1Very low57.1Low188 Ų18884 Ų8482%0.81747%0.474SS*.  trans-42.8107.5167.1-75.5177.5177.8174.10107.9G18 A22G18-K20 PolarHBondContact O-N 3.35Å; G18-K20 VanDerWaalsContact O-N 3.14Å; K20-A22 PolarHBondContact O-N 3.48Å
21T41.4Very low58.8Low127 Ų12782 Ų8278%0.77946%0.457SS*.  trans-6883.9169.545.90000106.3M19 K23M19-T21 PolarHBondContact O-N 2.9Å; T21-K23 PolarHBondContact O-N 2.94Å
22A53.8Low59.9Low57 Ų5777.3 Ų77.347%0.47144%0.435SS..PPolyproline II helixtrans-53.7126.8168.100000106.2K20 A24K20-A22 PolarHBondContact O-N 3.48Å; A22-A24 PolarHBondContact O-N 3.27Å; A22-A24 VanDerWaalsContact O-N 3.14Å
23K68.7Low60.9Low183 Ų18377.4 Ų77.480%0.79643%0.427SS*.PPolyproline II helixtrans-46.3127.4173.5-75.8-177.1176.1-177.40107.9T21 K25T21-K23 PolarHBondContact O-N 2.94Å; K23-K25 VanDerWaalsContact O-CD 3.32Å; K23-K25 WeakPolarHBondContact O-CD 3.42Å; K23-K25 WeakPolarHBondContact O-CG 3.49Å; K23-K25 PolarHBondContact O-N 3.08Å
24A80.6Confident62.1Low59 Ų5973.9 Ų73.949%0.48841%0.406SS..PPolyproline II helixtrans-46.3125.9178.400000109.9A22 G53A22-A24 PolarHBondContact O-N 3.27Å; A22-A24 VanDerWaalsContact O-N 3.14Å; A24-G53 WeakPolarHBondContact CB-O 2.77Å
25K90.4Very high64Low57 Ų5767.9 Ų67.925%0.24838%0.375CS..PPolyproline II helixtrans-97.6145.7-178.3-62.1-52.5-151.6155.50110.7K23 H54 N55 D138 L448K23-K25 VanDerWaalsContact O-CD 3.32Å; K23-K25 WeakPolarHBondContact O-CD 3.42Å; K23-K25 WeakPolarHBondContact O-CG 3.49Å; K23-K25 PolarHBondContact O-N 3.08Å; K25-H54 PolarHBondContact N-ND1 3.07Å; K25-N55 PolarHBondContact O-N 3.15Å; K25-D138 WeakPolarHBondContact CA-OD2 3.08Å; K25-D138 HydrophobicContact CB-CB 3.97Å; K25-D138 HydrophobicContact CD-CB 4.19Å; K25-D138 WeakPolarHBondContact CD-OD1 3.47Å; K25-D138 HydrophobicContact CG-CB 4.46Å; K25-D138 IonicContact NZ-OD1 3.25Å; K25-D138 PolarHBondContact NZ-OD1 3.33Å; K25-L448 HydrophobicContact CB-CD1 4.01Å; K25-L448 HydrophobicContact CB-CD2 4.36Å; K25-L448 HydrophobicContact CG-CB 4.4Å; K25-L448 HydrophobicContact CG-CD1 4.04Å; K25-L448 HydrophobicContact CG-CD2 4.19Å; K25-L448 HydrophobicContact CG-CG 4.45Å
26H91.7Very high66Low83 Ų8364.3 Ų64.338%0.38435%0.35SS..EExtended strand (participates in β ladder)trans-89.1112.6176.1-65.3-79.3000110.1N55 W137 D138 L139H26-N55 WeakPolarHBondContact CA-O 3.36Å; H26-N55 PolarHBondContact CE1-ND2 2.61Å; H26-N55 PolarHBondContact ND1-ND2 3.1Å; H26-W137 HydrophobicContact CB-CE3 4.04Å; H26-W137 HydrophobicContact CB-CZ3 4.43Å; H26-D138 PolarHBondContact N-OD2 2.92Å; H26-D138 PolarHBondContact O-N 3.46Å; H26-L139 PolarHBondContact O-N 3.37Å
27I93.3Very high68.3Low0 Ų059 Ų590%032%0.324CS..EExtended strand (participates in β ladder)trans-115.9132-176.3-53.6176.7000109.2F29 L49 H54 N55 V56 S57 L139 I141 I444 L448I27-F29 HydrophobicContact CG2-CD2 4.36Å; I27-F29 HydrophobicContact CG2-CE2 4.05Å; I27-L49 HydrophobicContact CD1-CB 4.46Å; I27-L49 HydrophobicContact CD1-CD1 4.07Å; I27-L49 HydrophobicContact CD1-CD2 4.13Å; I27-L49 HydrophobicContact CD1-CG 4.47Å; I27-H54 HydrophobicContact CD1-CB 3.82Å; I27-H54 HydrophobicContact CG1-CB 4.43Å; I27-N55 PolarHBondContact N-O 3.18Å; I27-V56 WeakPolarHBondContact O-CA 3.45Å; I27-S57 PolarHBondContact O-N 3.14Å; I27-L139 WeakPolarHBondContact CA-O 3.44Å; I27-L139 HydrophobicContact CG1-CB 4.47Å; I27-L139 HydrophobicContact CG2-CD2 4.48Å; I27-I141 HydrophobicContact CG2-CD1 3.66Å; I27-I141 HydrophobicContact CG2-CG1 4.07Å; I27-I444 HydrophobicContact CD1-CG2 4.33Å; I27-L448 HydrophobicContact CD1-CD1 3.97Å
28L91.2Very high70.7Confident0 Ų053 Ų530%030%0.297CS..EExtended strand (participates in β ladder)trans-115.7119.9177.7-177.267.8000111.8M30 S57 V59 I76 L132 W137 L139 L140 I141L28-M30 HydrophobicContact CD2-CE 4.22Å; L28-M30 HydrophobicContact CD2-CG 3.86Å; L28-M30 HydrophobicContact CD2-SD 3.87Å; L28-M30 HydrophobicContact CG-CG 3.89Å; L28-M30 HydrophobicContact CG-SD 4.49Å; L28-S57 WeakPolarHBondContact CA-O 3.26Å; L28-V59 HydrophobicContact CD1-CG2 3.87Å; L28-V59 HydrophobicContact CD2-CG2 4.4Å; L28-V59 HydrophobicContact CG-CG2 4.37Å; L28-I76 HydrophobicContact CD1-CD1 4.08Å; L28-L132 HydrophobicContact CD2-CD1 3.43Å; L28-L132 VanDerWaalsContact CD2-CD1 3.43Å; L28-L132 HydrophobicContact CD2-CD2 4.43Å; L28-L132 HydrophobicContact CD2-CG 4.17Å; L28-W137 HydrophobicContact CB-CD2 3.8Å; L28-W137 HydrophobicContact CB-CE3 3.58Å; L28-W137 HydrophobicContact CB-CG 4.48Å; L28-W137 HydrophobicContact CB-CH2 4.07Å; L28-W137 HydrophobicContact CB-CZ2 4.28Å; L28-W137 HydrophobicContact CB-CZ3 3.72Å; L28-W137 HydrophobicContact CD1-CH2 3.74Å; L28-W137 HydrophobicContact CD1-CZ2 3.99Å; L28-W137 HydrophobicContact CD1-CZ3 4.17Å; L28-W137 HydrophobicContact CD2-CD2 4.37Å; L28-W137 HydrophobicContact CD2-CZ2 4.05Å; L28-W137 HydrophobicContact CG-CH2 4.32Å; L28-W137 HydrophobicContact CG-CZ2 4.33Å; L28-W137 HydrophobicContact CG-CZ3 4.45Å; L28-L139 PolarHBondContact N-O 2.87Å; L28-L139 VanDerWaalsContact N-O 3.08Å; L28-L140 HydrophobicContact CB-CD2 3.97Å; L28-L140 HydrophobicContact CD2-CD2 4.07Å; L28-I141 PolarHBondContact O-N 3.12Å
29F91.5Very high73.4Confident0 Ų050 Ų500%027%0.265CS..EExtended strand (participates in β ladder)trans-88.4134.8168.8-76.2-99.1000111.3I27 M42 L45 A46 L49 V56 S57 L58 V59 I141 Y159I27-F29 HydrophobicContact CG2-CD2 4.36Å; I27-F29 HydrophobicContact CG2-CE2 4.05Å; F29-M42 HydrophobicContact CB-SD 4.31Å; F29-M42 HydrophobicContact CD1-CB 3.91Å; F29-M42 HydrophobicContact CD1-CG 4.19Å; F29-M42 HydrophobicContact CD1-SD 3.8Å; F29-M42 HydrophobicContact CE1-CB 4.33Å; F29-L45 HydrophobicContact CE1-CD2 4.18Å; F29-L45 HydrophobicContact CE1-CG 4.42Å; F29-L45 HydrophobicContact CZ-CB 4.46Å; F29-L45 HydrophobicContact CZ-CD2 4.27Å; F29-L45 HydrophobicContact CZ-CG 4.14Å; F29-A46 HydrophobicContact CD2-CB 4.01Å; F29-A46 HydrophobicContact CE2-CB 3.75Å; F29-A46 HydrophobicContact CZ-CB 4.02Å; F29-L49 HydrophobicContact CE2-CD1 3.81Å; F29-L49 HydrophobicContact CZ-CD1 3.68Å; F29-V56 HydrophobicContact CD2-CG1 3.59Å; F29-V56 HydrophobicContact CE2-CG1 3.64Å; F29-S57 PolarHBondContact N-O 2.92Å; F29-L58 HydrophobicContact CB-CB 4.17Å; F29-L58 HydrophobicContact CB-CD1 3.9Å; F29-L58 HydrophobicContact CB-CG 3.8Å; F29-L58 HydrophobicContact CG-CD1 4.45Å; F29-V59 PolarHBondContact O-N 3.11Å; F29-I141 HydrophobicContact CD1-CB 3.97Å; F29-I141 HydrophobicContact CD1-CD1 4.44Å; F29-I141 HydrophobicContact CD1-CG2 3.88Å; F29-I141 HydrophobicContact CD2-CD1 4.49Å; F29-I141 HydrophobicContact CE1-CB 4.13Å; F29-I141 HydrophobicContact CE1-CD1 3.85Å; F29-I141 HydrophobicContact CE1-CG2 3.82Å; F29-I141 HydrophobicContact CE2-CD1 3.89Å; F29-I141 HydrophobicContact CG-CB 4.32Å; F29-I141 HydrophobicContact CZ-CD1 3.54Å; F29-Y159 HydrophobicContact CE1-CD2 4.25Å; F29-Y159 HydrophobicContact CE1-CE2 4.45Å
30M85.5Confident75.8Confident5 Ų546.4 Ų46.43%0.02525%0.245CC..EExtended strand (participates in β ladder)trans-130.880.4-180-47.317883.500110.1L28 V59 L132 I141 P142 S143 Y147L28-M30 HydrophobicContact CD2-CE 4.22Å; L28-M30 HydrophobicContact CD2-CG 3.86Å; L28-M30 HydrophobicContact CD2-SD 3.87Å; L28-M30 HydrophobicContact CG-CG 3.89Å; L28-M30 HydrophobicContact CG-SD 4.49Å; M30-V59 HydrophobicContact CE-CG2 4.47Å; M30-V59 HydrophobicContact CG-CG2 4.23Å; M30-L132 HydrophobicContact CE-CD2 3.74Å; M30-I141 PolarHBondContact N-O 3.27Å; M30-P142 HydrophobicContact CB-CB 4.28Å; M30-P142 WeakPolarHBondContact O-CA 3.22Å; M30-S143 PolarHBondContact O-N 3.38Å; M30-Y147 HydrophobicContact CB-CD2 4.08Å; M30-Y147 HydrophobicContact CB-CG 4.11Å; M30-Y147 HydrophobicContact CE-CG 4.27Å
31P81.4Confident78Confident3 Ų338.2 Ų38.22%0.01921%0.211CC..  trans-63.9139.5-178.223.8-31.7000112.5H38 V39 M42 L58 V59 Y147P31-H38 HydrophobicContact CB-CB 4.21Å; P31-V39 HydrophobicContact CB-CG2 4.33Å; P31-V39 HydrophobicContact CG-CG2 3.78Å; P31-M42 HydrophobicContact CB-CE 4.49Å; P31-M42 HydrophobicContact CB-SD 3.72Å; P31-M42 HydrophobicContact CG-SD 4.39Å; P31-L58 HydrophobicContact CG-CD2 4.24Å; P31-V59 WeakPolarHBondContact CD-O 3.39Å; P31-V59 WeakPolarHBondContact CG-O 3.43Å; P31-Y147 WeakPolarHBondContact O-CE2 3.43Å; P31-Y147 PolarHBondContact O-OH 2.76Å
32A71.5Confident80.3Confident9 Ų932.2 Ų32.27%0.07417%0.174CC..SBendtrans-60137.3174.600000109.8H38 S143A32-H38 WeakPolarHBondContact O-CB 3.45Å; A32-H38 VanDerWaalsContact O-CG 3.24Å; A32-H38 PolarHBondContact O-ND1 3.23Å; A32-S143 WeakPolarHBondContact CB-O 3.3Å; A32-S143 WeakPolarHBondContact CB-OG 3.47Å
33M63.1Low82Confident51 Ų5130.5 Ų30.525%0.25116%0.157SC..SBendtrans61.9166.9173.4-50.4-174.2-79.900113.2A35 H38 L85 I112 Y147M33-A35 PolarHBondContact O-N 3.42Å; M33-H38 WeakPolarHBondContact CE-CE1 3.44Å; M33-H38 VanDerWaalsContact CE-NE2 3.27Å; M33-H38 WeakPolarHBondContact CE-NE2 3.44Å; M33-L85 HydrophobicContact CB-CD2 3.99Å; M33-I112 HydrophobicContact CG-CG2 3.99Å; M33-I112 HydrophobicContact SD-CD1 3.94Å; M33-I112 HydrophobicContact SD-CG2 4.45Å; M33-Y147 PolarHBondContact N-OH 2.66Å
34A64.6Low83.1Confident4 Ų424.2 Ų24.23%0.03314%0.135CC..SBendtrans-85.416.1176.900000114.1P36 F61 M80A34-P36 WeakPolarHBondContact O-CD 3.31Å; A34-F61 HydrophobicContact CB-CB 3.56Å; A34-M80 HydrophobicContact CB-CE 4.14Å; A34-M80 HydrophobicContact CB-CG 3.88Å; A34-M80 HydrophobicContact CB-SD 3.01Å; A34-M80 WeakPolarHBondContact CB-SD 3.29Å
35A71.6Confident83.7Confident4 Ų421.5 Ų21.53%0.03311%0.112CC..  trans-77.4124.9-174.800000110.2M33 S37 H38 L85M33-A35 PolarHBondContact O-N 3.42Å; A35-S37 PolarHBondContact O-N 3.26Å; A35-H38 WeakPolarHBondContact O-CB 3.26Å; A35-H38 PolarHBondContact O-N 3.03Å; A35-L85 HydrophobicContact CB-CD1 3.73Å
36P78.8Confident83.8Confident13 Ų1318.8 Ų18.88%0.08410%0.1CC..Hα-helixtrans-54.2-29.1175.1-30.738.7000113.1A34 H38 K40 E66 I68A34-P36 WeakPolarHBondContact O-CD 3.31Å; P36-H38 VanDerWaalsContact C-N 3.28Å; P36-H38 PolarHBondContact O-N 2.98Å; P36-K40 WeakPolarHBondContact O-CB 3.41Å; P36-K40 VanDerWaalsContact O-CG 3.25Å; P36-K40 WeakPolarHBondContact O-CG 3.23Å; P36-K40 PolarHBondContact O-N 2.9Å; P36-E66 HydrophobicContact CG-CB 3.73Å; P36-E66 HydrophobicContact CG-CG 4.15Å; P36-I68 HydrophobicContact CB-CD1 3.85Å; P36-I68 HydrophobicContact CB-CG1 4.5Å; P36-I68 WeakPolarHBondContact O-CD1 3.34Å
37S79.4Confident83.9Confident22 Ų2219.1 Ų19.115%0.15410%0.101CC..Hα-helixtrans-62.8-32.1178.457.60000113.4A35 S41 K358A35-S37 PolarHBondContact O-N 3.26Å; S37-S41 PolarHBondContact O-N 3.02Å; S37-S41 PolarHBondContact O-OG 3.4Å; S37-K358 PolarHBondContact O-NZ 3.38Å
38H81.2Confident83.9Confident18 Ų1821 Ų218%0.08311%0.11CC..Hα-helixtrans-76.4-44.4-179.7-79.1-128.2000111.9P31 A32 M33 A35 P36 K40 S41 M42 T161 T162P31-H38 HydrophobicContact CB-CB 4.21Å; A32-H38 WeakPolarHBondContact O-CB 3.45Å; A32-H38 VanDerWaalsContact O-CG 3.24Å; A32-H38 PolarHBondContact O-ND1 3.23Å; M33-H38 WeakPolarHBondContact CE-CE1 3.44Å; M33-H38 VanDerWaalsContact CE-NE2 3.27Å; M33-H38 WeakPolarHBondContact CE-NE2 3.44Å; A35-H38 WeakPolarHBondContact O-CB 3.26Å; A35-H38 PolarHBondContact O-N 3.03Å; P36-H38 VanDerWaalsContact C-N 3.28Å; P36-H38 PolarHBondContact O-N 2.98Å; H38-K40 VanDerWaalsContact C-N 3.33Å; H38-K40 PolarHBondContact O-N 3.09Å; H38-S41 PolarHBondContact O-N 2.97Å; H38-M42 PolarHBondContact O-N 3.1Å; H38-T161 PolarHBondContact CE1-OG1 3.25Å; H38-T161 PolarHBondContact ND1-OG1 3.32Å; H38-T162 VanDerWaalsContact CE1-CG2 3.41Å; H38-T162 WeakPolarHBondContact CE1-CG2 3.14Å
39V86.2Confident84.1Confident2 Ų221 Ų211%0.01211%0.11CC..Hα-helixtrans-55.4-52.4170.6175.10000109.3P31 S41 M42 L43 L58 Q60 I68 F75P31-V39 HydrophobicContact CB-CG2 4.33Å; P31-V39 HydrophobicContact CG-CG2 3.78Å; V39-S41 PolarHBondContact O-N 3.16Å; V39-S41 VanDerWaalsContact O-N 3.15Å; V39-M42 PolarHBondContact O-N 3.29Å; V39-L43 HydrophobicContact CG1-CD1 4.45Å; V39-L43 HydrophobicContact CG1-CD2 4.47Å; V39-L43 HydrophobicContact CG1-CG 4.32Å; V39-L43 WeakPolarHBondContact O-CG 3.42Å; V39-L43 PolarHBondContact O-N 3.29Å; V39-L43 VanDerWaalsContact O-N 3.13Å; V39-L58 HydrophobicContact CG1-CD2 3.75Å; V39-L58 HydrophobicContact CG2-CD2 4.41Å; V39-Q60 HydrophobicContact CG2-CB 4.36Å; V39-Q60 HydrophobicContact CG2-CG 4Å; V39-I68 HydrophobicContact CB-CD1 3.74Å; V39-I68 HydrophobicContact CG1-CB 4.47Å; V39-I68 HydrophobicContact CG1-CD1 3.67Å; V39-I68 HydrophobicContact CG2-CD1 4.46Å; V39-F75 HydrophobicContact CG1-CE1 3.99Å
40K86.3Confident84.2Confident90 Ų9022.8 Ų22.839%0.39112%0.119SC..Hα-helixtrans-56.8-31.1179.4-73.9174.4-176.1178.70113.5P36 H38 P44 I68P36-K40 WeakPolarHBondContact O-CB 3.41Å; P36-K40 VanDerWaalsContact O-CG 3.25Å; P36-K40 WeakPolarHBondContact O-CG 3.23Å; P36-K40 PolarHBondContact O-N 2.9Å; H38-K40 VanDerWaalsContact C-N 3.33Å; H38-K40 PolarHBondContact O-N 3.09Å; K40-P44 WeakPolarHBondContact O-CD 3.38Å; K40-I68 HydrophobicContact CD-CD1 4.48Å; K40-I68 HydrophobicContact CG-CD1 3.87Å
41S85.8Confident84.6Confident16 Ų1628.3 Ų28.311%0.11215%0.149CC..Hα-helixtrans-71.7-29.9177.2-62.90000113.2S37 H38 V39 Y159S37-S41 PolarHBondContact O-N 3.02Å; S37-S41 PolarHBondContact O-OG 3.4Å; H38-S41 PolarHBondContact O-N 2.97Å; V39-S41 PolarHBondContact O-N 3.16Å; V39-S41 VanDerWaalsContact O-N 3.15Å; S41-Y159 PolarHBondContact O-OH 3.01Å
42M89.6Confident85Confident0 Ų031.9 Ų31.90%017%0.167CC..Hα-helixtrans-87-25.3178.9-68.5-175.6160.600113.5F29 P31 H38 V39 P44 L45 A46 L58 S143 Y159 T161F29-M42 HydrophobicContact CB-SD 4.31Å; F29-M42 HydrophobicContact CD1-CB 3.91Å; F29-M42 HydrophobicContact CD1-CG 4.19Å; F29-M42 HydrophobicContact CD1-SD 3.8Å; F29-M42 HydrophobicContact CE1-CB 4.33Å; P31-M42 HydrophobicContact CB-CE 4.49Å; P31-M42 HydrophobicContact CB-SD 3.72Å; P31-M42 HydrophobicContact CG-SD 4.39Å; H38-M42 PolarHBondContact O-N 3.1Å; V39-M42 PolarHBondContact O-N 3.29Å; M42-P44 VanDerWaalsContact C-CD 3.47Å; M42-L45 PolarHBondContact O-N 3.38Å; M42-A46 PolarHBondContact O-N 3.26Å; M42-L58 HydrophobicContact CB-CD1 4.43Å; M42-S143 VanDerWaalsContact CE-CB 3.5Å; M42-Y159 HydrophobicContact CB-CE2 4.39Å; M42-Y159 HydrophobicContact CE-CD2 3.9Å; M42-Y159 HydrophobicContact CE-CG 3.89Å; M42-Y159 HydrophobicContact CG-CD2 4.03Å; M42-Y159 HydrophobicContact CG-CE2 3.88Å; M42-T161 HydrophobicContact CE-CG2 3.72Å; M42-T161 HydrophobicContact CG-CG2 3.78Å; M42-T161 HydrophobicContact SD-CG2 4.38Å
43L90.6Very high86.1Confident22 Ų2233.5 Ų33.512%0.11519%0.185CC..Hα-helixtrans-52.7-42.3-175.6-73.8176.6000115V39 L45 A46 K47 L58 I68 I73 F75V39-L43 HydrophobicContact CG1-CD1 4.45Å; V39-L43 HydrophobicContact CG1-CD2 4.47Å; V39-L43 HydrophobicContact CG1-CG 4.32Å; V39-L43 WeakPolarHBondContact O-CG 3.42Å; V39-L43 PolarHBondContact O-N 3.29Å; V39-L43 VanDerWaalsContact O-N 3.13Å; L43-L45 VanDerWaalsContact C-N 3.35Å; L43-L45 PolarHBondContact O-N 3.12Å; L43-A46 PolarHBondContact O-N 3.21Å; L43-K47 WeakPolarHBondContact O-CB 3.49Å; L43-K47 WeakPolarHBondContact O-CG 3.48Å; L43-K47 PolarHBondContact O-N 3.05Å; L43-L58 HydrophobicContact CD2-CD1 4.02Å; L43-I68 HydrophobicContact CD1-CG2 4.17Å; L43-I73 HydrophobicContact CD2-CD1 3.49Å; L43-I73 VanDerWaalsContact CD2-CD1 3.49Å; L43-F75 HydrophobicContact CD2-CZ 3.89Å
44P90.2Very high87.5Confident51 Ų5131.8 Ų31.833%0.33118%0.177SC..Hα-helixtrans-58.3-46179.3-26.336000112.6K40 M42 K47 E48 T437K40-P44 WeakPolarHBondContact O-CD 3.38Å; M42-P44 VanDerWaalsContact C-CD 3.47Å; P44-K47 PolarHBondContact O-N 2.88Å; P44-E48 PolarHBondContact O-N 2.98Å; P44-T437 HydrophobicContact CB-CG2 4.19Å; P44-T437 WeakPolarHBondContact O-CG2 3.5Å
45L93Very high88.9Confident1 Ų134.9 Ų34.91%0.00519%0.193CC..Hα-helixtrans-68-40.3178.3-175.661.6000111.9F29 M42 L43 K47 E48 L49 Y159 I234 I254 T437 I444F29-L45 HydrophobicContact CE1-CD2 4.18Å; F29-L45 HydrophobicContact CE1-CG 4.42Å; F29-L45 HydrophobicContact CZ-CB 4.46Å; F29-L45 HydrophobicContact CZ-CD2 4.27Å; F29-L45 HydrophobicContact CZ-CG 4.14Å; M42-L45 PolarHBondContact O-N 3.38Å; L43-L45 VanDerWaalsContact C-N 3.35Å; L43-L45 PolarHBondContact O-N 3.12Å; L45-K47 VanDerWaalsContact C-N 3.3Å; L45-K47 PolarHBondContact O-N 2.91Å; L45-E48 PolarHBondContact O-N 3.2Å; L45-L49 HydrophobicContact CG-CD1 4.35Å; L45-L49 WeakPolarHBondContact O-CG 3.29Å; L45-L49 PolarHBondContact O-N 2.79Å; L45-Y159 HydrophobicContact CB-CE2 4.47Å; L45-Y159 HydrophobicContact CD2-CD2 4.08Å; L45-Y159 HydrophobicContact CD2-CE2 3.67Å; L45-I234 HydrophobicContact CD2-CD1 4.28Å; L45-I254 HydrophobicContact CD1-CD1 3.98Å; L45-I254 HydrophobicContact CD2-CD1 3.54Å; L45-I254 HydrophobicContact CG-CD1 4.29Å; L45-T437 HydrophobicContact CB-CG2 4.29Å; L45-T437 HydrophobicContact CD1-CG2 4.25Å; L45-I444 HydrophobicContact CD1-CD1 4.16Å; L45-I444 HydrophobicContact CD2-CD1 3.8Å; L45-I444 HydrophobicContact CG-CD1 4.17Å
46A94.2Very high90Very high0 Ų034.8 Ų34.80%019%0.191CC..Hα-helixtrans-59.6-41174.900000112F29 M42 L43 L50 V56 I73F29-A46 HydrophobicContact CD2-CB 4.01Å; F29-A46 HydrophobicContact CE2-CB 3.75Å; F29-A46 HydrophobicContact CZ-CB 4.02Å; M42-A46 PolarHBondContact O-N 3.26Å; L43-A46 PolarHBondContact O-N 3.21Å; A46-L50 WeakPolarHBondContact O-CG 3.38Å; A46-L50 PolarHBondContact O-N 3.33Å; A46-L50 VanDerWaalsContact O-N 3.15Å; A46-V56 HydrophobicContact CB-CG1 3.9Å; A46-I73 HydrophobicContact CB-CD1 3.88Å
47K93.6Very high90.6Very high91 Ų9134.3 Ų34.340%0.39619%0.188SC..Hα-helixtrans-67.9-39.8175.8-71.8-177.7179.6-172.30112.4L43 P44 L45 L49 L50 N51 I73L43-K47 WeakPolarHBondContact O-CB 3.49Å; L43-K47 WeakPolarHBondContact O-CG 3.48Å; L43-K47 PolarHBondContact O-N 3.05Å; P44-K47 PolarHBondContact O-N 2.88Å; L45-K47 VanDerWaalsContact C-N 3.3Å; L45-K47 PolarHBondContact O-N 2.91Å; K47-L49 VanDerWaalsContact C-N 3.33Å; K47-L49 PolarHBondContact O-N 2.92Å; K47-L50 WeakPolarHBondContact O-CB 3.5Å; K47-L50 PolarHBondContact O-N 3.47Å; K47-N51 VanDerWaalsContact O-CG 3.28Å; K47-N51 PolarHBondContact O-N 2.99Å; K47-N51 PolarHBondContact O-ND2 3.32Å; K47-I73 HydrophobicContact CG-CD1 3.8Å
48E93Very high91.2Very high39 Ų3933.2 Ų33.218%0.18218%0.181CC..Hα-helixtrans-65-38.5177.3-165.863.4-173.300111.8P44 L45 L50 N51 D52 T437 K438P44-E48 PolarHBondContact O-N 2.98Å; L45-E48 PolarHBondContact O-N 3.2Å; E48-L50 VanDerWaalsContact C-N 3.33Å; E48-L50 PolarHBondContact O-N 3.27Å; E48-N51 WeakPolarHBondContact O-CB 3.36Å; E48-N51 PolarHBondContact O-N 3.36Å; E48-N51 VanDerWaalsContact O-N 3.12Å; E48-N51 PolarHBondContact OE2-ND2 2.84Å; E48-D52 PolarHBondContact O-N 3.28Å; E48-T437 HydrophobicContact CB-CG2 3.75Å; E48-T437 HydrophobicContact CG-CG2 4.31Å; E48-K438 HydrophobicContact CG-CG 4.47Å; E48-K438 WeakPolarHBondContact OE1-CG 3.3Å
49L94.7Very high91.4Very high0 Ų032.5 Ų32.50%018%0.178CC..Hα-helixtrans-66.7-32.6174.4-71.5166000113.2I27 F29 L45 K47 D52 G53 H54 V56 I141 S441 I444I27-L49 HydrophobicContact CD1-CB 4.46Å; I27-L49 HydrophobicContact CD1-CD1 4.07Å; I27-L49 HydrophobicContact CD1-CD2 4.13Å; I27-L49 HydrophobicContact CD1-CG 4.47Å; F29-L49 HydrophobicContact CE2-CD1 3.81Å; F29-L49 HydrophobicContact CZ-CD1 3.68Å; L45-L49 HydrophobicContact CG-CD1 4.35Å; L45-L49 WeakPolarHBondContact O-CG 3.29Å; L45-L49 PolarHBondContact O-N 2.79Å; K47-L49 VanDerWaalsContact C-N 3.33Å; K47-L49 PolarHBondContact O-N 2.92Å; L49-D52 PolarHBondContact O-N 3.43Å; L49-G53 PolarHBondContact O-N 3.1Å; L49-H54 WeakPolarHBondContact O-CB 3.46Å; L49-H54 PolarHBondContact O-CD2 2.79Å; L49-H54 PolarHBondContact O-N 3.32Å; L49-H54 VanDerWaalsContact O-N 3.09Å; L49-V56 HydrophobicContact CB-CG2 3.82Å; L49-I141 HydrophobicContact CD1-CD1 4.35Å; L49-S441 VanDerWaalsContact CD2-OG 3.32Å; L49-S441 WeakPolarHBondContact CD2-OG 3.5Å; L49-I444 HydrophobicContact CD1-CD1 3.91Å; L49-I444 HydrophobicContact CD1-CG2 4.25Å; L49-I444 HydrophobicContact CD2-CB 4Å; L49-I444 HydrophobicContact CD2-CD1 4.41Å; L49-I444 HydrophobicContact CD2-CG2 3.61Å
50L94Very high91.4Very high38 Ų3832.4 Ų32.420%0.19918%0.177CC..Hα-helixtrans-63.8-42.4169.8-74.4170.2000111.1A46 K47 E48 D52 G53 H54 V56 S72 I73A46-L50 WeakPolarHBondContact O-CG 3.38Å; A46-L50 PolarHBondContact O-N 3.33Å; A46-L50 VanDerWaalsContact O-N 3.15Å; K47-L50 WeakPolarHBondContact O-CB 3.5Å; K47-L50 PolarHBondContact O-N 3.47Å; E48-L50 VanDerWaalsContact C-N 3.33Å; E48-L50 PolarHBondContact O-N 3.27Å; L50-D52 PolarHBondContact O-N 3.19Å; L50-G53 WeakPolarHBondContact O-CA 3.46Å; L50-G53 PolarHBondContact O-N 3.36Å; L50-H54 WeakPolarHBondContact CD2-O 3.34Å; L50-V56 HydrophobicContact CD2-CB 3.74Å; L50-V56 HydrophobicContact CD2-CG2 3.85Å; L50-V56 HydrophobicContact CG-CB 3.82Å; L50-V56 HydrophobicContact CG-CG2 3.79Å; L50-S72 VanDerWaalsContact CD1-O 3.22Å; L50-S72 WeakPolarHBondContact CD1-O 3.29Å; L50-I73 HydrophobicContact CD1-CB 4.48Å; L50-I73 HydrophobicContact CD1-CD1 4.47Å; L50-I73 HydrophobicContact CD1-CG1 3.46Å; L50-I73 VanDerWaalsContact CD1-CG1 3.46Å
51N92.9Very high91Very high121 Ų12128.8 Ų28.865%0.64716%0.162SC*.Hα-helixtrans-63.5-32.1176.5-63.3-25.1000112K47 E48 G53K47-N51 VanDerWaalsContact O-CG 3.28Å; K47-N51 PolarHBondContact O-N 2.99Å; K47-N51 PolarHBondContact O-ND2 3.32Å; E48-N51 WeakPolarHBondContact O-CB 3.36Å; E48-N51 PolarHBondContact O-N 3.36Å; E48-N51 VanDerWaalsContact O-N 3.12Å; E48-N51 PolarHBondContact OE2-ND2 2.84Å; N51-G53 PolarHBondContact O-N 3.04Å
52D91.7Very high90.4Very high77 Ų7730.1 Ų30.141%0.41216%0.164SC..THydrogen-bonded Turntrans-71.2-3.1171.9-77.3-7.9000113.4E48 L49 L50 S441 S445E48-D52 PolarHBondContact O-N 3.28Å; L49-D52 PolarHBondContact O-N 3.43Å; L50-D52 PolarHBondContact O-N 3.19Å; D52-S441 PolarHBondContact OD2-OG 3.15Å; D52-S445 PolarHBondContact OD2-OG 3.11Å
53G92.7Very high89.7Confident43 Ų4332.6 Ų32.644%0.44318%0.177SC..THydrogen-bonded Turntrans90.212.5176.500000115A24 L49 L50 N51A24-G53 WeakPolarHBondContact CB-O 2.77Å; L49-G53 PolarHBondContact O-N 3.1Å; L50-G53 WeakPolarHBondContact O-CA 3.46Å; L50-G53 PolarHBondContact O-N 3.36Å; N51-G53 PolarHBondContact O-N 3.04Å
54H94.1Very high88.8Confident16 Ų1640.2 Ų40.27%0.07421%0.213CC..  trans-81.8158.8174.5-58.2-61.2000111.7K25 I27 L49 L50 V56 S445K25-H54 PolarHBondContact N-ND1 3.07Å; I27-H54 HydrophobicContact CD1-CB 3.82Å; I27-H54 HydrophobicContact CG1-CB 4.43Å; L49-H54 WeakPolarHBondContact O-CB 3.46Å; L49-H54 PolarHBondContact O-CD2 2.79Å; L49-H54 PolarHBondContact O-N 3.32Å; L49-H54 VanDerWaalsContact O-N 3.09Å; L50-H54 WeakPolarHBondContact CD2-O 3.34Å; H54-V56 HydrophobicContact CB-CG2 4.36Å; H54-S445 PolarHBondContact NE2-OG 2.83Å
55N93Very high88Confident69 Ų6941.8 Ų41.837%0.36924%0.238SC..EExtended strand (participates in β ladder)trans-94.4111.4170.5-175.7-12.6000109.1K25 H26 I27K25-N55 PolarHBondContact O-N 3.15Å; H26-N55 WeakPolarHBondContact CA-O 3.36Å; H26-N55 PolarHBondContact CE1-ND2 2.61Å; H26-N55 PolarHBondContact ND1-ND2 3.1Å; I27-N55 PolarHBondContact N-O 3.18Å
56V94.5Very high87.3Confident1 Ų145.4 Ų45.41%0.00626%0.255CS..EExtended strand (participates in β ladder)trans-110.1124.2-173.3-174.50000110.7I27 F29 A46 L49 L50 H54I27-V56 WeakPolarHBondContact O-CA 3.45Å; F29-V56 HydrophobicContact CD2-CG1 3.59Å; F29-V56 HydrophobicContact CE2-CG1 3.64Å; A46-V56 HydrophobicContact CB-CG1 3.9Å; L49-V56 HydrophobicContact CB-CG2 3.82Å; L50-V56 HydrophobicContact CD2-CB 3.74Å; L50-V56 HydrophobicContact CD2-CG2 3.85Å; L50-V56 HydrophobicContact CG-CB 3.82Å; L50-V56 HydrophobicContact CG-CG2 3.79Å; H54-V56 HydrophobicContact CB-CG2 4.36Å
57S92.2Very high86.8Confident3 Ų350 Ų502%0.02128%0.275CS..EExtended strand (participates in β ladder)trans-112.2151168.4-62.50000110.8I27 L28 F29 N74I27-S57 PolarHBondContact O-N 3.14Å; L28-S57 WeakPolarHBondContact CA-O 3.26Å; F29-S57 PolarHBondContact N-O 2.92Å; S57-N74 CarbonylContact C-O 3.56Å; S57-N74 WeakPolarHBondContact CA-O 3.41Å; S57-N74 PolarHBondContact OG-ND2 3.31Å
58L91.5Very high86.4Confident0 Ų046.6 Ų46.60%026%0.261CS..EExtended strand (participates in β ladder)trans-135.3125.6179.8-170.5150000110.5F29 P31 V39 M42 L43 Q60 I73 N74 F75 I76F29-L58 HydrophobicContact CB-CB 4.17Å; F29-L58 HydrophobicContact CB-CD1 3.9Å; F29-L58 HydrophobicContact CB-CG 3.8Å; F29-L58 HydrophobicContact CG-CD1 4.45Å; P31-L58 HydrophobicContact CG-CD2 4.24Å; V39-L58 HydrophobicContact CG1-CD2 3.75Å; V39-L58 HydrophobicContact CG2-CD2 4.41Å; M42-L58 HydrophobicContact CB-CD1 4.43Å; L43-L58 HydrophobicContact CD2-CD1 4.02Å; L58-Q60 HydrophobicContact CD2-CB 4.47Å; L58-I73 HydrophobicContact CB-CG2 3.86Å; L58-N74 PolarHBondContact N-O 2.84Å; L58-F75 HydrophobicContact CD2-CD1 3.87Å; L58-F75 HydrophobicContact CD2-CE1 3.66Å; L58-F75 CarbonylContact O-C 3.57Å; L58-F75 WeakPolarHBondContact O-CA 3.49Å; L58-I76 PolarHBondContact O-N 2.84Å
59V86.3Confident86.1Confident3 Ų349.8 Ų49.82%0.01828%0.283CS..EExtended strand (participates in β ladder)trans-77.6130.9174.1-177.20000109.5L28 F29 M30 P31 F61 I76 L78 F128L28-V59 HydrophobicContact CD1-CG2 3.87Å; L28-V59 HydrophobicContact CD2-CG2 4.4Å; L28-V59 HydrophobicContact CG-CG2 4.37Å; F29-V59 PolarHBondContact O-N 3.11Å; M30-V59 HydrophobicContact CE-CG2 4.47Å; M30-V59 HydrophobicContact CG-CG2 4.23Å; P31-V59 WeakPolarHBondContact CD-O 3.39Å; P31-V59 WeakPolarHBondContact CG-O 3.43Å; V59-F61 HydrophobicContact CG1-CD2 4.31Å; V59-F61 HydrophobicContact CG1-CE2 3.9Å; V59-I76 WeakPolarHBondContact CA-O 3.44Å; V59-L78 HydrophobicContact CG1-CD1 3.84Å; V59-F128 HydrophobicContact CG1-CZ 4.1Å; V59-F128 HydrophobicContact CG2-CE2 4.43Å; V59-F128 HydrophobicContact CG2-CZ 4.08Å
60Q84.9Confident85.7Confident0 Ų051.1 Ų51.10%029%0.292CS..EExtended strand (participates in β ladder)trans-127.6115171179.2176.115.900110.4V39 L58 E66 I68 F75 I76 Y77 L78V39-Q60 HydrophobicContact CG2-CB 4.36Å; V39-Q60 HydrophobicContact CG2-CG 4Å; L58-Q60 HydrophobicContact CD2-CB 4.47Å; Q60-E66 PolarHBondContact NE2-O 3.32Å; Q60-E66 VanDerWaalsContact NE2-O 3.15Å; Q60-I68 VanDerWaalsContact NE2-N 3.17Å; Q60-I68 PolarHBondContact OE1-O 3.44Å; Q60-I68 VanDerWaalsContact OE1-O 3.08Å; Q60-F75 HydrophobicContact CB-CD1 4.04Å; Q60-I76 PolarHBondContact N-O 2.8Å; Q60-Y77 HydrophobicContact CB-CD1 4.21Å; Q60-Y77 HydrophobicContact CB-CE1 4.41Å; Q60-Y77 WeakPolarHBondContact O-CA 3.47Å; Q60-L78 PolarHBondContact O-N 2.95Å
61F77.6Confident85.2Confident14 Ų1457.6 Ų57.66%0.06133%0.327CS..EExtended strand (participates in β ladder)trans-74.4130.7158.7-64.6-94.5000108.5A34 V59 L78 M80 Y147A34-F61 HydrophobicContact CB-CB 3.56Å; V59-F61 HydrophobicContact CG1-CD2 4.31Å; V59-F61 HydrophobicContact CG1-CE2 3.9Å; F61-L78 CarbonylContact C-O 3.53Å; F61-L78 VanDerWaalsContact CA-O 3.26Å; F61-L78 WeakPolarHBondContact CA-O 3.37Å; F61-L78 HydrophobicContact CD1-CB 3.71Å; F61-L78 HydrophobicContact CD1-CD1 4.06Å; F61-L78 HydrophobicContact CE1-CB 3.87Å; F61-L78 HydrophobicContact CE1-CD1 3.41Å; F61-L78 VanDerWaalsContact CE1-CD1 3.41Å; F61-L78 HydrophobicContact CE1-CG 4.29Å; F61-L78 HydrophobicContact CE2-CD1 3.88Å; F61-L78 HydrophobicContact CG-CB 4.24Å; F61-L78 HydrophobicContact CZ-CB 4.47Å; F61-L78 HydrophobicContact CZ-CD1 3.3Å; F61-M80 HydrophobicContact CB-CG 4.25Å; F61-Y147 HydrophobicContact CD2-CE1 4.18Å; F61-Y147 WeakPolarHBondContact CD2-OH 3.38Å; F61-Y147 HydrophobicContact CE2-CD1 4.15Å; F61-Y147 AromaticContact CE2-CE1 3.19Å; F61-Y147 HydrophobicContact CE2-CE1 3.19Å; F61-Y147 AromaticContact CE2-CZ 3.48Å; F61-Y147 VanDerWaalsContact CE2-CZ 3.48Å; F61-Y147 VanDerWaalsContact CE2-OH 3.23Å; F61-Y147 WeakPolarHBondContact CE2-OH 3.45Å; F61-Y147 HydrophobicContact CZ-CD1 4.39Å; F61-Y147 AromaticContact CZ-CE1 3.52Å; F61-Y147 HydrophobicContact CZ-CE1 3.52Å
62Y74.4Confident84.9Confident43 Ų4355.9 Ų55.917%0.16933%0.325CS..EExtended strand (participates in β ladder)trans-141.8148.8-176.375.6-71.5000112.4K67 Y77 L78 P79 M80Y62-K67 HydrophobicContact CD2-CB 3.83Å; Y62-K67 HydrophobicContact CD2-CD 4.13Å; Y62-K67 HydrophobicContact CD2-CG 4.02Å; Y62-K67 HydrophobicContact CE2-CB 4.47Å; Y62-K67 HydrophobicContact CE2-CD 4.02Å; Y62-K67 HydrophobicContact CE2-CG 4.41Å; Y62-K67 HydrophobicContact CG-CB 4.38Å; Y62-K67 HydrophobicContact CG-CG 4.35Å; Y62-Y77 HydrophobicContact CD1-CD1 4.07Å; Y62-Y77 HydrophobicContact CD1-CG 4.48Å; Y62-Y77 HydrophobicContact CE1-CD1 4.33Å; Y62-Y77 HydrophobicContact CE1-CG 4.31Å; Y62-L78 VanDerWaalsContact CD1-O 3.32Å; Y62-L78 WeakPolarHBondContact CD1-O 3.31Å; Y62-L78 PolarHBondContact N-O 3.26Å; Y62-P79 HydrophobicContact CE1-CB 4.41Å; Y62-M80 PolarHBondContact O-N 3.46Å; Y62-M80 VanDerWaalsContact O-N 3.11Å
63N75.3Confident84.9Confident52 Ų5252.6 Ų52.628%0.27831%0.307SS..  trans-91.8151.8152.7-59.9-50.6000108G65 E66N63-G65 PolarHBondContact O-N 3.08Å; N63-E66 HydrophobicContact CB-CB 4.49Å; N63-E66 HydrophobicContact CB-CG 4.49Å; N63-E66 PolarHBondContact ND2-OE2 3.27Å; N63-E66 PolarHBondContact O-N 2.96Å
64E72Confident84.8Confident183 Ų18354.2 Ų54.286%0.85531%0.306SS*.G310 helixtrans-52.2-37.5-172-68-165.2156.100114.3E66E64-E66 VanDerWaalsContact C-N 3.29Å; E64-E66 PolarHBondContact O-N 2.84Å
65G73.1Confident84.6Confident84 Ų8454.3 Ų54.387%0.86631%0.306SS*.G310 helixtrans-78-3.2177.700000116N63N63-G65 PolarHBondContact O-N 3.08Å
66E77.2Confident84.3Confident76 Ų7652.8 Ų52.836%0.35530%0.297SS..G310 helixtrans-119.85.7-171.1-67.8-171.9135.900113.2P36 Q60 N63 E64 I68P36-E66 HydrophobicContact CG-CB 3.73Å; P36-E66 HydrophobicContact CG-CG 4.15Å; Q60-E66 PolarHBondContact NE2-O 3.32Å; Q60-E66 VanDerWaalsContact NE2-O 3.15Å; N63-E66 HydrophobicContact CB-CB 4.49Å; N63-E66 HydrophobicContact CB-CG 4.49Å; N63-E66 PolarHBondContact ND2-OE2 3.27Å; N63-E66 PolarHBondContact O-N 2.96Å; E64-E66 VanDerWaalsContact C-N 3.29Å; E64-E66 PolarHBondContact O-N 2.84Å; E66-I68 PolarHBondContact O-N 3.25Å
67K84.6Confident83.8Confident96 Ų9655.8 Ų55.842%0.41731%0.309SS..  trans-62.6130.2-179.2-164.9173.8-177.61740110.9Y62 Y77Y62-K67 HydrophobicContact CD2-CB 3.83Å; Y62-K67 HydrophobicContact CD2-CD 4.13Å; Y62-K67 HydrophobicContact CD2-CG 4.02Å; Y62-K67 HydrophobicContact CE2-CB 4.47Å; Y62-K67 HydrophobicContact CE2-CD 4.02Å; Y62-K67 HydrophobicContact CE2-CG 4.41Å; Y62-K67 HydrophobicContact CG-CB 4.38Å; Y62-K67 HydrophobicContact CG-CG 4.35Å; K67-Y77 HydrophobicContact CD-CD1 4.3Å; K67-Y77 HydrophobicContact CD-CE1 4.08Å; K67-Y77 VanDerWaalsContact CE-CE2 3.4Å; K67-Y77 HydrophobicContact CG-CD1 3.99Å; K67-Y77 HydrophobicContact CG-CE1 3.55Å
68I85.4Confident83.1Confident21 Ų2156 Ų5611%0.10831%0.31CS..  trans-104.7135.7174.5-64.2163.4000107.7P36 V39 K40 L43 Q60 E66 F75 Y77P36-I68 HydrophobicContact CB-CD1 3.85Å; P36-I68 HydrophobicContact CB-CG1 4.5Å; P36-I68 WeakPolarHBondContact O-CD1 3.34Å; V39-I68 HydrophobicContact CB-CD1 3.74Å; V39-I68 HydrophobicContact CG1-CB 4.47Å; V39-I68 HydrophobicContact CG1-CD1 3.67Å; V39-I68 HydrophobicContact CG2-CD1 4.46Å; K40-I68 HydrophobicContact CD-CD1 4.48Å; K40-I68 HydrophobicContact CG-CD1 3.87Å; L43-I68 HydrophobicContact CD1-CG2 4.17Å; Q60-I68 VanDerWaalsContact NE2-N 3.17Å; Q60-I68 PolarHBondContact OE1-O 3.44Å; Q60-I68 VanDerWaalsContact OE1-O 3.08Å; E66-I68 PolarHBondContact O-N 3.25Å; I68-F75 HydrophobicContact CB-CE1 4.45Å; I68-F75 HydrophobicContact CG2-CE1 4.35Å; I68-F75 HydrophobicContact CG2-CZ 3.96Å; I68-Y77 WeakPolarHBondContact O-CE1 3.46Å; I68-Y77 PolarHBondContact O-OH 3.5Å
69T86.8Confident82.3Confident106 Ų10659.6 Ų59.665%0.6533%0.333SS*.  trans-121.4154.3176.156.60000109.9
70S86Confident81.4Confident27 Ų2761.5 Ų61.519%0.18934%0.342CS..  trans-152.6136.7170.9-171.50000108S72S70-S72 PolarHBondContact O-N 3.43Å
71D83.5Confident80.2Confident175 Ų17565.4 Ų65.494%0.93637%0.369SS*.SBendtrans-66.6-25.1-178.2-54-33.1000112.8
72S86.8Confident79.1Confident85 Ų8574.1 Ų74.159%0.59441%0.411SS*.SBendtrans-97.9-22.6-174.1-360000115L50 S70L50-S72 VanDerWaalsContact CD1-O 3.22Å; L50-S72 WeakPolarHBondContact CD1-O 3.29Å; S70-S72 PolarHBondContact O-N 3.43Å
73I90.7Very high78.3Confident8 Ų874.1 Ų74.14%0.04142%0.419CS..SBendtrans-104.8129.7-173.9-69.9168.6000109.2L43 A46 K47 L50 L58 F75L43-I73 HydrophobicContact CD2-CD1 3.49Å; L43-I73 VanDerWaalsContact CD2-CD1 3.49Å; A46-I73 HydrophobicContact CB-CD1 3.88Å; K47-I73 HydrophobicContact CG-CD1 3.8Å; L50-I73 HydrophobicContact CD1-CB 4.48Å; L50-I73 HydrophobicContact CD1-CD1 4.47Å; L50-I73 HydrophobicContact CD1-CG1 3.46Å; L50-I73 VanDerWaalsContact CD1-CG1 3.46Å; L58-I73 HydrophobicContact CB-CG2 3.86Å; I73-F75 HydrophobicContact CB-CD2 4.38Å; I73-F75 HydrophobicContact CB-CE2 4.03Å; I73-F75 HydrophobicContact CG2-CD2 4.13Å; I73-F75 HydrophobicContact CG2-CE2 4Å; I73-F75 HydrophobicContact CG2-CZ 4.44Å; I73-F75 WeakPolarHBondContact O-CD2 3.48Å; I73-F75 PolarHBondContact O-N 3.02Å; I73-F75 VanDerWaalsContact O-N 3.16Å
74N91Very high77.5Confident77 Ų7774.7 Ų74.741%0.41243%0.428SS..EExtended strand (participates in β ladder)trans-75.3102.4172.1179.549.8000110.4S57 L58S57-N74 CarbonylContact C-O 3.56Å; S57-N74 WeakPolarHBondContact CA-O 3.41Å; S57-N74 PolarHBondContact OG-ND2 3.31Å; L58-N74 PolarHBondContact N-O 2.84Å
75F90.5Very high77Confident18 Ų1867.3 Ų67.38%0.07939%0.394CS..EExtended strand (participates in β ladder)trans-81.8135.8174.8-76.8-94.7000111.5V39 L43 L58 Q60 I68 I73 Y77V39-F75 HydrophobicContact CG1-CE1 3.99Å; L43-F75 HydrophobicContact CD2-CZ 3.89Å; L58-F75 HydrophobicContact CD2-CD1 3.87Å; L58-F75 HydrophobicContact CD2-CE1 3.66Å; L58-F75 CarbonylContact O-C 3.57Å; L58-F75 WeakPolarHBondContact O-CA 3.49Å; Q60-F75 HydrophobicContact CB-CD1 4.04Å; I68-F75 HydrophobicContact CB-CE1 4.45Å; I68-F75 HydrophobicContact CG2-CE1 4.35Å; I68-F75 HydrophobicContact CG2-CZ 3.96Å; I73-F75 HydrophobicContact CB-CD2 4.38Å; I73-F75 HydrophobicContact CB-CE2 4.03Å; I73-F75 HydrophobicContact CG2-CD2 4.13Å; I73-F75 HydrophobicContact CG2-CE2 4Å; I73-F75 HydrophobicContact CG2-CZ 4.44Å; I73-F75 WeakPolarHBondContact O-CD2 3.48Å; I73-F75 PolarHBondContact O-N 3.02Å; I73-F75 VanDerWaalsContact O-N 3.16Å; F75-Y77 HydrophobicContact CB-CD1 4.34Å; F75-Y77 HydrophobicContact CB-CD2 4.12Å; F75-Y77 HydrophobicContact CB-CE1 3.74Å; F75-Y77 HydrophobicContact CB-CE2 3.51Å; F75-Y77 WeakPolarHBondContact CB-OH 3.37Å; F75-Y77 HydrophobicContact CD1-CE1 4.08Å; F75-Y77 HydrophobicContact CG-CE1 4.05Å; F75-Y77 HydrophobicContact CG-CE2 4.44Å; F75-Y77 AromaticContact CG-CZ 3.75Å; F75-Y77 WeakPolarHBondContact CG-OH 3.34Å
76I85.9Confident76.8Confident36 Ų3664.3 Ų64.319%0.18536%0.357CS..EExtended strand (participates in β ladder)trans-106.3107.5166-47.7171.1000107.3L28 L58 V59 Q60 F128L28-I76 HydrophobicContact CD1-CD1 4.08Å; L58-I76 PolarHBondContact O-N 2.84Å; V59-I76 WeakPolarHBondContact CA-O 3.44Å; Q60-I76 PolarHBondContact N-O 2.8Å; I76-F128 HydrophobicContact CB-CE2 4.25Å; I76-F128 HydrophobicContact CG2-CD2 3.67Å; I76-F128 HydrophobicContact CG2-CE2 3.44Å; I76-F128 VanDerWaalsContact CG2-CE2 3.44Å
77Y84.1Confident76.7Confident65 Ų6562.7 Ų62.726%0.25535%0.351SS..EExtended strand (participates in β ladder)trans-88.4135.1-173.1-67.2-68.6000111.6Q60 Y62 K67 I68 F75Q60-Y77 HydrophobicContact CB-CD1 4.21Å; Q60-Y77 HydrophobicContact CB-CE1 4.41Å; Q60-Y77 WeakPolarHBondContact O-CA 3.47Å; Y62-Y77 HydrophobicContact CD1-CD1 4.07Å; Y62-Y77 HydrophobicContact CD1-CG 4.48Å; Y62-Y77 HydrophobicContact CE1-CD1 4.33Å; Y62-Y77 HydrophobicContact CE1-CG 4.31Å; K67-Y77 HydrophobicContact CD-CD1 4.3Å; K67-Y77 HydrophobicContact CD-CE1 4.08Å; K67-Y77 VanDerWaalsContact CE-CE2 3.4Å; K67-Y77 HydrophobicContact CG-CD1 3.99Å; K67-Y77 HydrophobicContact CG-CE1 3.55Å; I68-Y77 WeakPolarHBondContact O-CE1 3.46Å; I68-Y77 PolarHBondContact O-OH 3.5Å; F75-Y77 HydrophobicContact CB-CD1 4.34Å; F75-Y77 HydrophobicContact CB-CD2 4.12Å; F75-Y77 HydrophobicContact CB-CE1 3.74Å; F75-Y77 HydrophobicContact CB-CE2 3.51Å; F75-Y77 WeakPolarHBondContact CB-OH 3.37Å; F75-Y77 HydrophobicContact CD1-CE1 4.08Å; F75-Y77 HydrophobicContact CG-CE1 4.05Å; F75-Y77 HydrophobicContact CG-CE2 4.44Å; F75-Y77 AromaticContact CG-CZ 3.75Å; F75-Y77 WeakPolarHBondContact CG-OH 3.34Å
78L77.5Confident76.4Confident7 Ų766.9 Ų66.94%0.03737%0.37CS..EExtended strand (participates in β ladder)trans-125.3115.4173.6-70.9174.6000109.9V59 Q60 F61 Y62 Q125 F128V59-L78 HydrophobicContact CG1-CD1 3.84Å; Q60-L78 PolarHBondContact O-N 2.95Å; F61-L78 CarbonylContact C-O 3.53Å; F61-L78 VanDerWaalsContact CA-O 3.26Å; F61-L78 WeakPolarHBondContact CA-O 3.37Å; F61-L78 HydrophobicContact CD1-CB 3.71Å; F61-L78 HydrophobicContact CD1-CD1 4.06Å; F61-L78 HydrophobicContact CE1-CB 3.87Å; F61-L78 HydrophobicContact CE1-CD1 3.41Å; F61-L78 VanDerWaalsContact CE1-CD1 3.41Å; F61-L78 HydrophobicContact CE1-CG 4.29Å; F61-L78 HydrophobicContact CE2-CD1 3.88Å; F61-L78 HydrophobicContact CG-CB 4.24Å; F61-L78 HydrophobicContact CZ-CB 4.47Å; F61-L78 HydrophobicContact CZ-CD1 3.3Å; Y62-L78 VanDerWaalsContact CD1-O 3.32Å; Y62-L78 WeakPolarHBondContact CD1-O 3.31Å; Y62-L78 PolarHBondContact N-O 3.26Å; L78-Q125 HydrophobicContact CD2-CG 4.49Å; L78-F128 HydrophobicContact CD1-CD1 3.87Å; L78-F128 HydrophobicContact CD1-CD2 4.24Å; L78-F128 HydrophobicContact CD1-CE1 3.61Å; L78-F128 HydrophobicContact CD1-CE2 3.98Å; L78-F128 HydrophobicContact CD1-CG 4.2Å; L78-F128 HydrophobicContact CD1-CZ 3.67Å; L78-F128 HydrophobicContact CD2-CB 3.85Å; L78-F128 HydrophobicContact CD2-CD1 3.94Å; L78-F128 HydrophobicContact CD2-CD2 3.72Å; L78-F128 HydrophobicContact CD2-CE1 4.48Å; L78-F128 HydrophobicContact CD2-CE2 4.25Å; L78-F128 HydrophobicContact CD2-CG 3.55Å; L78-F128 HydrophobicContact CG-CD1 4.46Å; L78-F128 HydrophobicContact CG-CD2 4.17Å; L78-F128 HydrophobicContact CG-CE2 4.21Å; L78-F128 HydrophobicContact CG-CG 4.31Å; L78-F128 HydrophobicContact CG-CZ 4.4Å
79P74.7Confident76.2Confident76 Ų7672.3 Ų72.349%0.49439%0.394SS..EExtended strand (participates in β ladder)trans-66.2138.2174.228.2-32.8000109.7Y62 Q125Y62-P79 HydrophobicContact CE1-CB 4.41Å; P79-Q125 PolarHBondContact O-NE2 3.18Å
80M68.5Low75.8Confident43 Ų4368 Ų6821%0.21237%0.367CS..  trans-81.6131167.4-74.3-165.37900110.6A34 F61 Y62 E82 A83A34-M80 HydrophobicContact CB-CE 4.14Å; A34-M80 HydrophobicContact CB-CG 3.88Å; A34-M80 HydrophobicContact CB-SD 3.01Å; A34-M80 WeakPolarHBondContact CB-SD 3.29Å; F61-M80 HydrophobicContact CB-CG 4.25Å; Y62-M80 PolarHBondContact O-N 3.46Å; Y62-M80 VanDerWaalsContact O-N 3.11Å; M80-E82 PolarHBondContact O-N 3.21Å; M80-A83 HydrophobicContact CE-CB 4.5Å; M80-A83 WeakPolarHBondContact CE-O 3.49Å
81S59.6Low75.6Confident81 Ų8167.7 Ų67.757%0.56636%0.363SS*.  trans-76.7102.4164.659.60000109.5A83S81-A83 PolarHBondContact O-N 2.87Å
82E54.5Low75.6Confident198 Ų19862 Ų6293%0.92533%0.334SS*.SBendtrans44-7.2164.5-67.6-166.7163.700121.8M80 S84M80-E82 PolarHBondContact O-N 3.21Å; E82-S84 PolarHBondContact O-N 2.96Å; E82-S84 VanDerWaalsContact O-N 3.17Å
83A56.1Low75.5Confident43 Ų4360 Ų6036%0.35532%0.318SS..  trans-8595.2178.800000109.9M80 S81 L85 A115M80-A83 HydrophobicContact CE-CB 4.5Å; M80-A83 WeakPolarHBondContact CE-O 3.49Å; S81-A83 PolarHBondContact O-N 2.87Å; A83-L85 PolarHBondContact O-N 3.49Å; A83-A115 HydrophobicContact CB-CB 4.43Å
84S59.5Low75.3Confident64 Ų6459.9 Ų59.945%0.44832%0.318SS..  trans-53.9141.6163.564.90000109.3E82 I86 D87E82-S84 PolarHBondContact O-N 2.96Å; E82-S84 VanDerWaalsContact O-N 3.17Å; S84-I86 PolarHBondContact O-N 2.95Å; S84-I86 VanDerWaalsContact O-N 3.09Å; S84-I86 VanDerWaalsContact OG-C 3.27Å; S84-I86 PolarHBondContact OG-O 2.96Å; S84-D87 WeakPolarHBondContact OG-CA 3.2Å; S84-D87 PolarHBondContact OG-N 3.1Å
85L60.9Low75.2Confident28 Ų2856.3 Ų56.315%0.14730%0.298CS..SBendtrans-56.2-29.1178.2-73.7168.9000112.5M33 A35 A83 I112M33-L85 HydrophobicContact CB-CD2 3.99Å; A35-L85 HydrophobicContact CB-CD1 3.73Å; A83-L85 PolarHBondContact O-N 3.49Å; L85-I112 HydrophobicContact CD2-CD1 3.93Å; L85-I112 HydrophobicContact CD2-CG1 3.96Å; L85-I112 HydrophobicContact CD2-CG2 4.27Å
86I69.7Low75.1Confident20 Ų2062.8 Ų62.810%0.10332%0.323CS..SBendtrans-133.3113.7175.8-52.2178.7000106.8S84 Q90 Q91 I94 L288 F376S84-I86 PolarHBondContact O-N 2.95Å; S84-I86 VanDerWaalsContact O-N 3.09Å; S84-I86 VanDerWaalsContact OG-C 3.27Å; S84-I86 PolarHBondContact OG-O 2.96Å; I86-Q90 HydrophobicContact CG2-CB 3.5Å; I86-Q90 VanDerWaalsContact CG2-CB 3.5Å; I86-Q91 HydrophobicContact CB-CG 4.48Å; I86-Q91 HydrophobicContact CG2-CB 4.41Å; I86-Q91 HydrophobicContact CG2-CG 3.68Å; I86-I94 HydrophobicContact CD1-CD1 3.82Å; I86-I94 HydrophobicContact CG1-CD1 4.44Å; I86-I94 HydrophobicContact CG2-CD1 3.63Å; I86-L288 HydrophobicContact CD1-CB 3.83Å; I86-L288 HydrophobicContact CD1-CD1 4.26Å; I86-L288 HydrophobicContact CD1-CD2 4.11Å; I86-L288 HydrophobicContact CD1-CG 4.28Å; I86-F376 HydrophobicContact CD1-CE1 4.24Å; I86-F376 HydrophobicContact CD1-CZ 3.77Å
87D74.8Confident75Confident43 Ų4368.6 Ų68.623%0.2334%0.342CS..  trans-78.1173.1173.664.339.1000111.8S84 E89 Q90 Q91 K111S84-D87 WeakPolarHBondContact OG-CA 3.2Å; S84-D87 PolarHBondContact OG-N 3.1Å; D87-E89 VanDerWaalsContact C-N 3.27Å; D87-E89 PolarHBondContact O-N 2.86Å; D87-E89 WeakPolarHBondContact OD1-CA 3.44Å; D87-E89 WeakPolarHBondContact OD1-CB 3.33Å; D87-E89 PolarHBondContact OD1-N 3.47Å; D87-E89 VanDerWaalsContact OD1-N 3.08Å; D87-Q90 PolarHBondContact O-N 2.92Å; D87-Q90 WeakPolarHBondContact OD1-CB 3.43Å; D87-Q90 VanDerWaalsContact OD1-CG 3.3Å; D87-Q90 WeakPolarHBondContact OD1-CG 2.92Å; D87-Q90 PolarHBondContact OD1-N 2.78Å; D87-Q90 PolarHBondContact OD2-OE1 2.62Å; D87-Q91 WeakPolarHBondContact O-CG 3.4Å; D87-Q91 PolarHBondContact O-N 3.31Å; D87-K111 IonicContact OD2-NZ 3.26Å; D87-K111 PolarHBondContact OD2-NZ 3.41Å
88K78.3Confident74.8Confident184 Ų18470.3 Ų70.380%0.835%0.348SS*.Hα-helixtrans-59.8-35-179.5-73-176.2177.4179.40113.1T92K88-T92 WeakPolarHBondContact O-CB 3.43Å; K88-T92 PolarHBondContact O-N 2.93Å; K88-T92 PolarHBondContact O-OG1 2.54Å
89E80.6Confident74.2Confident134 Ų13470.6 Ų70.663%0.62635%0.352SS*.Hα-helixtrans-67.9-43.4177.9-172.1-163.1164.400110.5D87 T92 T93D87-E89 VanDerWaalsContact C-N 3.27Å; D87-E89 PolarHBondContact O-N 2.86Å; D87-E89 WeakPolarHBondContact OD1-CA 3.44Å; D87-E89 WeakPolarHBondContact OD1-CB 3.33Å; D87-E89 PolarHBondContact OD1-N 3.47Å; D87-E89 VanDerWaalsContact OD1-N 3.08Å; E89-T92 PolarHBondContact O-N 2.84Å; E89-T93 WeakPolarHBondContact O-CB 3.32Å; E89-T93 PolarHBondContact O-N 3.13Å; E89-T93 PolarHBondContact O-OG1 2.96Å
90Q77.6Confident73.7Confident17 Ų1769.2 Ų69.28%0.07934%0.343CS..Hα-helixtrans-67.1-41.2176-70.6173.2-53.300111.4I86 D87 T92 T93 I94 S108I86-Q90 HydrophobicContact CG2-CB 3.5Å; I86-Q90 VanDerWaalsContact CG2-CB 3.5Å; D87-Q90 PolarHBondContact O-N 2.92Å; D87-Q90 WeakPolarHBondContact OD1-CB 3.43Å; D87-Q90 VanDerWaalsContact OD1-CG 3.3Å; D87-Q90 WeakPolarHBondContact OD1-CG 2.92Å; D87-Q90 PolarHBondContact OD1-N 2.78Å; D87-Q90 PolarHBondContact OD2-OE1 2.62Å; Q90-T92 VanDerWaalsContact C-N 3.34Å; Q90-T92 PolarHBondContact O-N 2.89Å; Q90-T93 PolarHBondContact O-N 3.04Å; Q90-I94 WeakPolarHBondContact O-CB 3.34Å; Q90-I94 WeakPolarHBondContact O-CD1 3.35Å; Q90-I94 WeakPolarHBondContact O-CG1 3.5Å; Q90-I94 PolarHBondContact O-N 2.89Å; Q90-S108 PolarHBondContact NE2-OG 2.58Å
91Q83Confident73.7Confident20 Ų2069.5 Ų69.59%0.09335%0.345CS..Hα-helixtrans-56.6-50.2172.9-76-62.2-13.300110.3I86 D87 T93 I94 W95 L288 D290I86-Q91 HydrophobicContact CB-CG 4.48Å; I86-Q91 HydrophobicContact CG2-CB 4.41Å; I86-Q91 HydrophobicContact CG2-CG 3.68Å; D87-Q91 WeakPolarHBondContact O-CG 3.4Å; D87-Q91 PolarHBondContact O-N 3.31Å; Q91-T93 VanDerWaalsContact C-N 3.31Å; Q91-T93 PolarHBondContact O-N 3.46Å; Q91-I94 WeakPolarHBondContact O-CB 3.38Å; Q91-I94 PolarHBondContact O-N 3.01Å; Q91-W95 PolarHBondContact O-N 3.3Å; Q91-L288 PolarHBondContact NE2-O 3.06Å; Q91-L288 PolarHBondContact OE1-O 2.99Å; Q91-D290 HydrophobicContact CG-CB 4.29Å
92T84.1Confident73.9Confident56 Ų5667.4 Ų67.434%0.34433%0.329SS..Hα-helixtrans-58.8-43.4177.5-570000111.7K88 E89 Q90 W95 R96K88-T92 WeakPolarHBondContact O-CB 3.43Å; K88-T92 PolarHBondContact O-N 2.93Å; K88-T92 PolarHBondContact O-OG1 2.54Å; E89-T92 PolarHBondContact O-N 2.84Å; Q90-T92 VanDerWaalsContact C-N 3.34Å; Q90-T92 PolarHBondContact O-N 2.89Å; T92-W95 PolarHBondContact O-N 2.96Å; T92-R96 HydrophobicContact CG2-CG 4.44Å; T92-R96 WeakPolarHBondContact O-CB 3.18Å; T92-R96 WeakPolarHBondContact O-CG 3.4Å; T92-R96 PolarHBondContact O-N 3.08Å
93T84.1Confident74.5Confident41 Ų4165.9 Ų65.925%0.25232%0.315SS..Hα-helixtrans-65-43.4178.2-62.20000111.7E89 Q90 Q91 W95 R96 R97 T104E89-T93 WeakPolarHBondContact O-CB 3.32Å; E89-T93 PolarHBondContact O-N 3.13Å; E89-T93 PolarHBondContact O-OG1 2.96Å; Q90-T93 PolarHBondContact O-N 3.04Å; Q91-T93 VanDerWaalsContact C-N 3.31Å; Q91-T93 PolarHBondContact O-N 3.46Å; T93-W95 VanDerWaalsContact C-N 3.3Å; T93-W95 PolarHBondContact O-N 3.33Å; T93-R96 PolarHBondContact O-N 3.49Å; T93-R97 HydrophobicContact CG2-CG 3.82Å; T93-R97 VanDerWaalsContact O-CB 3.26Å; T93-R97 WeakPolarHBondContact O-CB 3.32Å; T93-R97 WeakPolarHBondContact O-CG 3.25Å; T93-R97 PolarHBondContact O-N 3.37Å; T93-T104 HydrophobicContact CG2-CG2 3.99Å
94I86.3Confident75Confident6 Ų664.9 Ų64.93%0.03131%0.305CS..Hα-helixtrans-57.3-47.2178.3-78.4163.8000109.3I86 Q90 Q91 L375 F376 K397I86-I94 HydrophobicContact CD1-CD1 3.82Å; I86-I94 HydrophobicContact CG1-CD1 4.44Å; I86-I94 HydrophobicContact CG2-CD1 3.63Å; Q90-I94 WeakPolarHBondContact O-CB 3.34Å; Q90-I94 WeakPolarHBondContact O-CD1 3.35Å; Q90-I94 WeakPolarHBondContact O-CG1 3.5Å; Q90-I94 PolarHBondContact O-N 2.89Å; Q91-I94 WeakPolarHBondContact O-CB 3.38Å; Q91-I94 PolarHBondContact O-N 3.01Å; I94-L375 HydrophobicContact CG2-CB 3.72Å; I94-F376 HydrophobicContact CB-CD1 4.32Å; I94-F376 HydrophobicContact CD1-CD1 3.78Å; I94-F376 HydrophobicContact CD1-CE1 3.77Å; I94-F376 HydrophobicContact CD1-CG 4.2Å; I94-F376 HydrophobicContact CD1-CZ 4.2Å; I94-F376 HydrophobicContact CG1-CB 4.32Å; I94-F376 HydrophobicContact CG1-CD1 3.84Å; I94-F376 HydrophobicContact CG1-CE1 4.35Å; I94-F376 HydrophobicContact CG1-CG 4.08Å; I94-F376 HydrophobicContact CG2-CD1 3.5Å; I94-F376 VanDerWaalsContact CG2-CD1 3.5Å; I94-F376 HydrophobicContact CG2-CE1 4.08Å; I94-F376 HydrophobicContact CG2-CG 4.36Å; I94-K397 WeakPolarHBondContact O-CE 3.17Å; I94-K397 PolarHBondContact O-NZ 3.25Å
95W89Confident75.4Confident2 Ų265 Ų651%0.00830%0.297CS..Hα-helixtrans-70.8-41.4-179.9-75.1110.8000114.1Q91 T92 T93 F285 A289 D290 W291 A294 L375 K397Q91-W95 PolarHBondContact O-N 3.3Å; T92-W95 PolarHBondContact O-N 2.96Å; T93-W95 VanDerWaalsContact C-N 3.3Å; T93-W95 PolarHBondContact O-N 3.33Å; W95-F285 AromaticContact CH2-CD2 3.63Å; W95-F285 HydrophobicContact CH2-CD2 3.63Å; W95-F285 AromaticContact CH2-CE2 3.81Å; W95-F285 HydrophobicContact CH2-CE2 3.81Å; W95-F285 HydrophobicContact CZ2-CD2 4.5Å; W95-F285 HydrophobicContact CZ3-CD2 4.21Å; W95-F285 AromaticContact CZ3-CE2 3.94Å; W95-F285 HydrophobicContact CZ3-CE2 3.94Å; W95-A289 HydrophobicContact CZ2-CB 4.37Å; W95-D290 PolarHBondContact NE1-O 3.21Å; W95-W291 AromaticContact CH2-CD2 3.89Å; W95-W291 HydrophobicContact CH2-CD2 3.89Å; W95-W291 AromaticContact CH2-CE3 3.64Å; W95-W291 HydrophobicContact CH2-CE3 3.64Å; W95-W291 AromaticContact CH2-CH2 3.94Å; W95-W291 HydrophobicContact CH2-CH2 3.94Å; W95-W291 HydrophobicContact CH2-CZ2 4.17Å; W95-W291 AromaticContact CH2-CZ3 3.67Å; W95-W291 HydrophobicContact CH2-CZ3 3.67Å; W95-W291 HydrophobicContact CZ2-CD2 4.14Å; W95-W291 HydrophobicContact CZ2-CE3 4.14Å; W95-W291 HydrophobicContact CZ2-CG 4.47Å; W95-W291 HydrophobicContact CZ3-CE3 4.34Å; W95-W291 HydrophobicContact CZ3-CH2 4.44Å; W95-W291 HydrophobicContact CZ3-CZ3 4.07Å; W95-A294 HydrophobicContact CD2-CB 3.62Å; W95-A294 HydrophobicContact CE3-CB 3.79Å; W95-A294 HydrophobicContact CG-CB 4.08Å; W95-A294 HydrophobicContact CH2-CB 4.1Å; W95-A294 HydrophobicContact CZ2-CB 3.98Å; W95-A294 HydrophobicContact CZ3-CB 4.01Å; W95-L375 HydrophobicContact CD2-CD2 4.43Å; W95-L375 HydrophobicContact CE3-CD2 3.89Å; W95-L375 HydrophobicContact CH2-CD1 4.48Å; W95-L375 HydrophobicContact CH2-CD2 4.14Å; W95-L375 HydrophobicContact CZ2-CD1 4.39Å; W95-L375 HydrophobicContact CZ3-CD2 3.73Å; W95-K397 WeakPolarHBondContact O-CE 3.5Å
96R88.1Confident75.7Confident155 Ų15564.6 Ų64.659%0.58530%0.295SS*.Hα-helixtrans-86.3-20.4-172.4-67.7-177.5-178.4-106.5-0.2114.6T92 T93 P295T92-R96 HydrophobicContact CG2-CG 4.44Å; T92-R96 WeakPolarHBondContact O-CB 3.18Å; T92-R96 WeakPolarHBondContact O-CG 3.4Å; T92-R96 PolarHBondContact O-N 3.08Å; T93-R96 PolarHBondContact O-N 3.49Å; R96-P295 HydrophobicContact CG-CG 3.99Å
97R84.7Confident75.7Confident158 Ų15870.7 Ų70.760%0.59632%0.321SS*.SBendtrans-99.6156179-60.2-62.3-174.1172-1110.9T93 K397 T398T93-R97 HydrophobicContact CG2-CG 3.82Å; T93-R97 VanDerWaalsContact O-CB 3.26Å; T93-R97 WeakPolarHBondContact O-CB 3.32Å; T93-R97 WeakPolarHBondContact O-CG 3.25Å; T93-R97 PolarHBondContact O-N 3.37Å; R97-K397 VanDerWaalsContact O-CE 3.29Å; R97-K397 WeakPolarHBondContact O-CE 3.34Å; R97-K397 PolarHBondContact O-NZ 2.7Å; R97-T398 VanDerWaalsContact C-CG2 3.46Å
98R79.7Confident75.3Confident101 Ų10169.3 Ų69.338%0.38132%0.315SS..  trans-58.2143.8168.5-75.5-168.8176.9-173.67.2109.2V100 E187 D396 T398R98-V100 PolarHBondContact O-N 2.66Å; R98-V100 VanDerWaalsContact O-N 3.16Å; R98-E187 IonicContact NH1-OE1 3.65Å; R98-E187 PolarHBondContact NH1-OE1 3.16Å; R98-D396 IonicContact CZ-OD2 3.2Å; R98-D396 IonicContact NE-OD2 2.56Å; R98-D396 PolarHBondContact NE-OD2 2.83Å; R98-D396 IonicContact NH2-OD2 3.69Å; R98-T398 HydrophobicContact CG-CG2 3.95Å
99G65.6Low74.8Confident12 Ų1261.6 Ų61.612%0.12429%0.285CS..SBendtrans-61.7-23.2176.700000112.9N101 L375 V380G99-N101 PolarHBondContact O-N 2.7Å; G99-L375 WeakPolarHBondContact CA-O 3.34Å; G99-V380 VanDerWaalsContact C-CG2 3.48Å
100V63.6Low74.3Confident48 Ų4859.3 Ų59.329%0.29127%0.271SS..  trans-75.866.3173.2-1690000110.1R98 S185 V380R98-V100 PolarHBondContact O-N 2.66Å; R98-V100 VanDerWaalsContact O-N 3.16Å; V100-S185 WeakPolarHBondContact CG1-O 3.36Å; V100-V380 HydrophobicContact CG2-CG1 3.94Å
101N67.1Low73.8Confident48 Ų4862.5 Ų62.526%0.25729%0.285SS..  trans-13498.7172.4-170.5-17.7000110.7G99 W103 T104 F105G99-N101 PolarHBondContact O-N 2.7Å; N101-W103 PolarHBondContact O-N 2.8Å; N101-W103 WeakPolarHBondContact OD1-CB 3.24Å; N101-W103 PolarHBondContact OD1-N 3.4Å; N101-T104 VanDerWaalsContact CG-OG1 3.31Å; N101-T104 PolarHBondContact ND2-OG1 3.03Å; N101-T104 VanDerWaalsContact ND2-OG1 3.14Å; N101-T104 PolarHBondContact O-N 3.43Å; N101-T104 PolarHBondContact OD1-N 2.96Å; N101-F105 PolarHBondContact O-N 2.9Å
102P64Low72.8Confident37 Ų3762.7 Ų62.724%0.2429%0.286CS..Hα-helixtrans-59.2-37.8178.722.8-31.7000111.3T104 F105 L106 V206P102-T104 PolarHBondContact O-N 3.47Å; P102-F105 WeakPolarHBondContact O-CB 3.41Å; P102-F105 PolarHBondContact O-N 2.76Å; P102-F105 VanDerWaalsContact O-N 3.17Å; P102-L106 VanDerWaalsContact O-CG 3.27Å; P102-L106 WeakPolarHBondContact O-CG 3.47Å; P102-L106 PolarHBondContact O-N 3.41Å; P102-V206 HydrophobicContact CB-CG1 4.32Å
103W67.3Low71.9Confident166 Ų16660.4 Ų60.463%0.62927%0.272SS*.Hα-helixtrans-63.6-37.5-179.3-65.6123.2000113.9N101 F105 L106 K107N101-W103 PolarHBondContact O-N 2.8Å; N101-W103 WeakPolarHBondContact OD1-CB 3.24Å; N101-W103 PolarHBondContact OD1-N 3.4Å; W103-F105 VanDerWaalsContact C-N 3.35Å; W103-L106 HydrophobicContact CE3-CD1 3.8Å; W103-L106 HydrophobicContact CZ3-CD1 3.74Å; W103-L106 PolarHBondContact O-N 3.35Å; W103-K107 WeakPolarHBondContact O-CB 3.33Å; W103-K107 WeakPolarHBondContact O-CG 3.24Å; W103-K107 PolarHBondContact O-N 3.3Å
104T67.5Low71Confident22 Ų2259.7 Ų59.714%0.13527%0.268CS..Hα-helixtrans-63.3-45.6175-57.40000110.3T93 N101 P102 K107 S108T93-T104 HydrophobicContact CG2-CG2 3.99Å; N101-T104 VanDerWaalsContact CG-OG1 3.31Å; N101-T104 PolarHBondContact ND2-OG1 3.03Å; N101-T104 VanDerWaalsContact ND2-OG1 3.14Å; N101-T104 PolarHBondContact O-N 3.43Å; N101-T104 PolarHBondContact OD1-N 2.96Å; P102-T104 PolarHBondContact O-N 3.47Å; T104-K107 PolarHBondContact O-N 2.63Å; T104-S108 PolarHBondContact O-N 2.99Å; T104-S108 PolarHBondContact O-OG 3.18Å; T104-S108 VanDerWaalsContact O-OG 3.09Å
105F67.3Low69.9Low66 Ų6660.8 Ų60.829%0.28928%0.278SS..Hα-helixtrans-61.7-46.8176.3177-98.8000111.5N101 P102 W103 K107 S108 A109 M184N101-F105 PolarHBondContact O-N 2.9Å; P102-F105 WeakPolarHBondContact O-CB 3.41Å; P102-F105 PolarHBondContact O-N 2.76Å; P102-F105 VanDerWaalsContact O-N 3.17Å; W103-F105 VanDerWaalsContact C-N 3.35Å; F105-K107 PolarHBondContact O-N 3.36Å; F105-S108 PolarHBondContact O-N 3.33Å; F105-A109 VanDerWaalsContact O-CB 3.3Å; F105-A109 WeakPolarHBondContact O-CB 3.45Å; F105-A109 PolarHBondContact O-N 3.46Å; F105-M184 HydrophobicContact CD1-CE 3.91Å; F105-M184 HydrophobicContact CE1-CE 3.89Å; F105-M184 HydrophobicContact CG-CE 4.31Å; F105-M184 HydrophobicContact CZ-CE 4.26Å
106L67.5Low68.6Low20 Ų2061.5 Ų61.511%0.10528%0.283CS..Hα-helixtrans-62.1-42178.6-65.9-171.4000112.2P102 W103 A109 W110 V206 F210P102-L106 VanDerWaalsContact O-CG 3.27Å; P102-L106 WeakPolarHBondContact O-CG 3.47Å; P102-L106 PolarHBondContact O-N 3.41Å; W103-L106 HydrophobicContact CE3-CD1 3.8Å; W103-L106 HydrophobicContact CZ3-CD1 3.74Å; W103-L106 PolarHBondContact O-N 3.35Å; L106-A109 PolarHBondContact O-N 3.05Å; L106-W110 WeakPolarHBondContact O-CB 3.47Å; L106-W110 PolarHBondContact O-N 3.03Å; L106-V206 HydrophobicContact CD1-CG1 4.21Å; L106-F210 HydrophobicContact CB-CD2 4.13Å; L106-F210 HydrophobicContact CB-CE2 4.18Å; L106-F210 HydrophobicContact CD1-CB 3.92Å; L106-F210 HydrophobicContact CD1-CD2 3.88Å; L106-F210 HydrophobicContact CD1-CG 4.07Å; L106-F210 HydrophobicContact CD2-CB 3.83Å; L106-F210 HydrophobicContact CD2-CD1 3.56Å; L106-F210 HydrophobicContact CD2-CD2 3.31Å; L106-F210 HydrophobicContact CD2-CE1 3.87Å; L106-F210 HydrophobicContact CD2-CE2 3.63Å; L106-F210 HydrophobicContact CD2-CG 3.25Å; L106-F210 HydrophobicContact CD2-CZ 3.9Å; L106-F210 HydrophobicContact CG-CD2 3.93Å; L106-F210 HydrophobicContact CG-CE2 4.34Å; L106-F210 HydrophobicContact CG-CG 4.18Å
107K69.4Low67.3Low148 Ų14858.1 Ų58.164%0.64327%0.273SS*.Hα-helixtrans-62.9-43.9175.3-78.8-176.6177.9-1720111.8W103 T104 F105 W110 K111W103-K107 WeakPolarHBondContact O-CB 3.33Å; W103-K107 WeakPolarHBondContact O-CG 3.24Å; W103-K107 PolarHBondContact O-N 3.3Å; T104-K107 PolarHBondContact O-N 2.63Å; F105-K107 PolarHBondContact O-N 3.36Å; K107-W110 PolarHBondContact O-N 3.49Å; K107-K111 PolarHBondContact O-N 3.17Å
108S67.4Low66.3Low15 Ų1559.2 Ų59.211%0.10528%0.277CS..Hα-helixtrans-65.6-46.8176.9-61.20000111.6Q90 T104 F105 W110 K111 I112Q90-S108 PolarHBondContact NE2-OG 2.58Å; T104-S108 PolarHBondContact O-N 2.99Å; T104-S108 PolarHBondContact O-OG 3.18Å; T104-S108 VanDerWaalsContact O-OG 3.09Å; F105-S108 PolarHBondContact O-N 3.33Å; S108-W110 VanDerWaalsContact C-N 3.3Å; S108-W110 PolarHBondContact O-N 3.48Å; S108-K111 PolarHBondContact O-N 2.93Å; S108-I112 WeakPolarHBondContact O-CB 3.21Å; S108-I112 WeakPolarHBondContact O-CD1 3.44Å; S108-I112 VanDerWaalsContact O-CG1 3.23Å; S108-I112 WeakPolarHBondContact O-CG1 3.28Å; S108-I112 PolarHBondContact O-N 3.14Å
109A67.7Low65.4Low22 Ų2255 Ų5518%0.18226%0.263CS..Hα-helixtrans-57.6-44.817500000110.9F105 L106 I112 S113 F210F105-A109 VanDerWaalsContact O-CB 3.3Å; F105-A109 WeakPolarHBondContact O-CB 3.45Å; F105-A109 PolarHBondContact O-N 3.46Å; L106-A109 PolarHBondContact O-N 3.05Å; A109-I112 PolarHBondContact O-N 2.83Å; A109-S113 VanDerWaalsContact O-CB 3.27Å; A109-S113 WeakPolarHBondContact O-CB 3.43Å; A109-S113 PolarHBondContact O-N 3.38Å; A109-S113 PolarHBondContact O-OG 2.63Å; A109-F210 HydrophobicContact CB-CZ 4.17Å
110W68.4Low65Low85 Ų8557.1 Ų57.132%0.32227%0.268SS..Hα-helixtrans-61.2-51.7176.5-176.1-90.3000112.6L106 K107 S108 I112 S113 T114 L213 L217L106-W110 WeakPolarHBondContact O-CB 3.47Å; L106-W110 PolarHBondContact O-N 3.03Å; K107-W110 PolarHBondContact O-N 3.49Å; S108-W110 VanDerWaalsContact C-N 3.3Å; S108-W110 PolarHBondContact O-N 3.48Å; W110-I112 VanDerWaalsContact C-N 3.34Å; W110-I112 PolarHBondContact O-N 2.71Å; W110-S113 WeakPolarHBondContact O-CB 3.42Å; W110-S113 PolarHBondContact O-N 3.13Å; W110-T114 HydrophobicContact CD2-CG2 4.47Å; W110-T114 HydrophobicContact CG-CG2 4.45Å; W110-T114 WeakPolarHBondContact O-CG2 3.33Å; W110-T114 PolarHBondContact O-N 2.86Å; W110-T114 PolarHBondContact O-OG1 3.41Å; W110-L213 HydrophobicContact CH2-CG 4.42Å; W110-L213 HydrophobicContact CZ3-CD2 4.18Å; W110-L213 HydrophobicContact CZ3-CG 4.16Å; W110-L217 HydrophobicContact CD2-CD1 4.07Å; W110-L217 HydrophobicContact CE3-CD1 3.69Å; W110-L217 HydrophobicContact CH2-CD1 3.06Å; W110-L217 HydrophobicContact CH2-CD2 3.88Å; W110-L217 HydrophobicContact CH2-CG 3.39Å; W110-L217 HydrophobicContact CZ2-CD1 3.43Å; W110-L217 VanDerWaalsContact CZ2-CD1 3.43Å; W110-L217 HydrophobicContact CZ2-CD2 4.07Å; W110-L217 HydrophobicContact CZ2-CG 4Å; W110-L217 HydrophobicContact CZ3-CD1 3.18Å; W110-L217 HydrophobicContact CZ3-CG 3.8Å
111K67.1Low64.9Low84 Ų8460.5 Ų60.537%0.36528%0.28SS..Hα-helixtrans-54.4-50.3177.3-82.3-176171.6-178.20111D87 K107 S108 S113 T114 A115D87-K111 IonicContact OD2-NZ 3.26Å; D87-K111 PolarHBondContact OD2-NZ 3.41Å; K107-K111 PolarHBondContact O-N 3.17Å; S108-K111 PolarHBondContact O-N 2.93Å; K111-S113 VanDerWaalsContact C-N 3.35Å; K111-S113 PolarHBondContact O-N 3.34Å; K111-T114 PolarHBondContact O-N 3.07Å; K111-T114 PolarHBondContact O-OG1 2.97Å; K111-A115 WeakPolarHBondContact O-CB 3.4Å; K111-A115 PolarHBondContact O-N 3.06Å
112I63.9Low64.8Low24 Ų2460.9 Ų60.912%0.12328%0.282CS..Hα-helixtrans-60-46178.4-66.4166000110.9M33 L85 S108 A109 W110 T114 A115 S116M33-I112 HydrophobicContact CG-CG2 3.99Å; M33-I112 HydrophobicContact SD-CD1 3.94Å; M33-I112 HydrophobicContact SD-CG2 4.45Å; L85-I112 HydrophobicContact CD2-CD1 3.93Å; L85-I112 HydrophobicContact CD2-CG1 3.96Å; L85-I112 HydrophobicContact CD2-CG2 4.27Å; S108-I112 WeakPolarHBondContact O-CB 3.21Å; S108-I112 WeakPolarHBondContact O-CD1 3.44Å; S108-I112 VanDerWaalsContact O-CG1 3.23Å; S108-I112 WeakPolarHBondContact O-CG1 3.28Å; S108-I112 PolarHBondContact O-N 3.14Å; A109-I112 PolarHBondContact O-N 2.83Å; W110-I112 VanDerWaalsContact C-N 3.34Å; W110-I112 PolarHBondContact O-N 2.71Å; I112-T114 PolarHBondContact O-N 3.27Å; I112-A115 PolarHBondContact O-N 3.4Å; I112-S116 PolarHBondContact O-N 3.21Å; I112-S116 PolarHBondContact O-OG 2.67Å
113S64Low64.8Low8 Ų867.3 Ų67.36%0.05631%0.309CS..Hα-helixtrans-62.1-44.1-179.6-56.60000112.3A109 W110 K111 F117 H146 F214A109-S113 VanDerWaalsContact O-CB 3.27Å; A109-S113 WeakPolarHBondContact O-CB 3.43Å; A109-S113 PolarHBondContact O-N 3.38Å; A109-S113 PolarHBondContact O-OG 2.63Å; W110-S113 WeakPolarHBondContact O-CB 3.42Å; W110-S113 PolarHBondContact O-N 3.13Å; K111-S113 VanDerWaalsContact C-N 3.35Å; K111-S113 PolarHBondContact O-N 3.34Å; S113-F117 VanDerWaalsContact O-CB 3.3Å; S113-F117 WeakPolarHBondContact O-CB 3.25Å; S113-F117 PolarHBondContact O-N 3.48Å; S113-H146 PolarHBondContact OG-CE1 3.14Å; S113-F214 VanDerWaalsContact CB-CE2 3.46Å; S113-F214 WeakPolarHBondContact OG-CE2 3.4Å; S113-F214 WeakPolarHBondContact OG-CZ 3.32Å
114T65.2Low64.5Low26 Ų2666 Ų6616%0.1631%0.314CS..Hα-helixtrans-68.1-36.8177.159.20000111.8W110 K111 I112 F117 R118 L217W110-T114 HydrophobicContact CD2-CG2 4.47Å; W110-T114 HydrophobicContact CG-CG2 4.45Å; W110-T114 WeakPolarHBondContact O-CG2 3.33Å; W110-T114 PolarHBondContact O-N 2.86Å; W110-T114 PolarHBondContact O-OG1 3.41Å; K111-T114 PolarHBondContact O-N 3.07Å; K111-T114 PolarHBondContact O-OG1 2.97Å; I112-T114 PolarHBondContact O-N 3.27Å; T114-F117 PolarHBondContact O-N 3.49Å; T114-R118 WeakPolarHBondContact O-CB 3.38Å; T114-R118 WeakPolarHBondContact O-CG 3.41Å; T114-R118 PolarHBondContact O-N 3.3Å; T114-L217 HydrophobicContact CG2-CD1 4.32Å
115A64.4Low64.5Low29 Ų2965.3 Ų65.324%0.2431%0.309CS..Hα-helixtrans-64.3-47.4174.800000111.4A83 K111 I112 F117 R118 S119A83-A115 HydrophobicContact CB-CB 4.43Å; K111-A115 WeakPolarHBondContact O-CB 3.4Å; K111-A115 PolarHBondContact O-N 3.06Å; I112-A115 PolarHBondContact O-N 3.4Å; A115-F117 PolarHBondContact O-N 3.47Å; A115-R118 PolarHBondContact O-N 2.89Å; A115-S119 WeakPolarHBondContact O-CB 3.31Å; A115-S119 PolarHBondContact O-N 3.37Å
116S60.9Low64.6Low18 Ų1864.8 Ų64.813%0.12631%0.311CS..Hα-helixtrans-63.8-37.5175-60.50000112.8I112 S119 R120I112-S116 PolarHBondContact O-N 3.21Å; I112-S116 PolarHBondContact O-OG 2.67Å; S116-S119 PolarHBondContact O-OG 3.44Å; S116-S119 VanDerWaalsContact O-OG 3.13Å; S116-R120 PolarHBondContact O-N 3.12Å
117F61.5Low64.7Low84 Ų8469.9 Ų69.937%0.36834%0.335SS..Hα-helixtrans-67-42.2174.8-179.6-94.4000112S113 T114 A115 R120 H121 L218S113-F117 VanDerWaalsContact O-CB 3.3Å; S113-F117 WeakPolarHBondContact O-CB 3.25Å; S113-F117 PolarHBondContact O-N 3.48Å; T114-F117 PolarHBondContact O-N 3.49Å; A115-F117 PolarHBondContact O-N 3.47Å; F117-R120 WeakPolarHBondContact O-CB 3.25Å; F117-R120 PolarHBondContact O-N 2.97Å; F117-H121 AromaticContact CE1-CE1 3.64Å; F117-H121 AromaticContact CE1-ND1 3.97Å; F117-H121 AromaticContact CE2-CE1 3.72Å; F117-H121 AromaticContact CZ-CE1 3.39Å; F117-H121 WeakPolarHBondContact CZ-CE1 3.18Å; F117-H121 PolarHBondContact O-ND1 2.89Å; F117-L218 HydrophobicContact CD2-CD2 3.54Å; F117-L218 HydrophobicContact CE2-CD2 3.98Å; F117-L218 HydrophobicContact CG-CD2 4.46Å
118R62.5Low64.9Low180 Ų18064 Ų6468%0.67931%0.309SS*.Hα-helixtrans-65.7-40.5175.8-75.2171.9-174.6165.70.9111.7T114 A115 R120 H121 N122T114-R118 WeakPolarHBondContact O-CB 3.38Å; T114-R118 WeakPolarHBondContact O-CG 3.41Å; T114-R118 PolarHBondContact O-N 3.3Å; A115-R118 PolarHBondContact O-N 2.89Å; R118-R120 PolarHBondContact O-N 3.45Å; R118-H121 CarbonylContact O-C 3.55Å; R118-H121 WeakPolarHBondContact O-CA 3.47Å; R118-H121 PolarHBondContact O-N 2.77Å; R118-N122 PolarHBondContact O-N 3.37Å; R118-N122 VanDerWaalsContact O-N 3.15Å
119S60.5Low65.1Low13 Ų1364.3 Ų64.39%0.09131%0.308CS..Hα-helixtrans-59.8-34178.6920000111.4A115 S116 H121 N122 Q125A115-S119 WeakPolarHBondContact O-CB 3.31Å; A115-S119 PolarHBondContact O-N 3.37Å; S116-S119 PolarHBondContact O-OG 3.44Å; S116-S119 VanDerWaalsContact O-OG 3.13Å; S119-H121 PolarHBondContact O-N 3.18Å; S119-N122 WeakPolarHBondContact O-CB 3.48Å; S119-N122 PolarHBondContact O-N 2.92Å; S119-N122 VanDerWaalsContact O-N 3.12Å; S119-Q125 VanDerWaalsContact C-OE1 3.24Å; S119-Q125 VanDerWaalsContact O-CB 3.3Å; S119-Q125 WeakPolarHBondContact O-CB 3.36Å; S119-Q125 PolarHBondContact O-OE1 2.9Å; S119-Q125 PolarHBondContact OG-OE1 3.38Å
120R58Low65.3Low57 Ų5768.9 Ų68.922%0.21533%0.326CS..THydrogen-bonded Turntrans-59.3-27.1172.6-169.7-176.5-62169.8-1.6114.6S116 F117 R118 Y129 H146 T149S116-R120 PolarHBondContact O-N 3.12Å; F117-R120 WeakPolarHBondContact O-CB 3.25Å; F117-R120 PolarHBondContact O-N 2.97Å; R118-R120 PolarHBondContact O-N 3.45Å; R120-Y129 VanDerWaalsContact CA-CE2 3.49Å; R120-Y129 HydrophobicContact CB-CD2 4.45Å; R120-Y129 HydrophobicContact CB-CE2 3.85Å; R120-Y129 HydrophobicContact CG-CD1 4.32Å; R120-Y129 HydrophobicContact CG-CD2 3.93Å; R120-Y129 HydrophobicContact CG-CE1 4.06Å; R120-Y129 HydrophobicContact CG-CE2 3.72Å; R120-Y129 HydrophobicContact CG-CG 4.25Å; R120-H146 PolarHBondContact NH2-O 3.09Å; R120-T149 VanDerWaalsContact NH1-CG2 3.3Å
121H60.9Low65.5Low118 Ų11868.8 Ų68.855%0.54633%0.331SS..THydrogen-bonded Turntrans-103.82.1-179.6-59.382.7000112.4F117 R118 S119F117-H121 AromaticContact CE1-CE1 3.64Å; F117-H121 AromaticContact CE1-ND1 3.97Å; F117-H121 AromaticContact CE2-CE1 3.72Å; F117-H121 AromaticContact CZ-CE1 3.39Å; F117-H121 WeakPolarHBondContact CZ-CE1 3.18Å; F117-H121 PolarHBondContact O-ND1 2.89Å; R118-H121 CarbonylContact O-C 3.55Å; R118-H121 WeakPolarHBondContact O-CA 3.47Å; R118-H121 PolarHBondContact O-N 2.77Å; S119-H121 PolarHBondContact O-N 3.18Å
122N66.4Low65.8Low57 Ų5765.4 Ų65.431%0.30532%0.318SS..SBendtrans-71.9130.8171.6-172.62.3000108.9R118 S119 D124 Q125 V126R118-N122 PolarHBondContact O-N 3.37Å; R118-N122 VanDerWaalsContact O-N 3.15Å; S119-N122 WeakPolarHBondContact O-CB 3.48Å; S119-N122 PolarHBondContact O-N 2.92Å; S119-N122 VanDerWaalsContact O-N 3.12Å; N122-D124 PolarHBondContact O-N 3.47Å; N122-Q125 PolarHBondContact O-N 2.83Å; N122-V126 WeakPolarHBondContact O-CG2 3.1Å; N122-V126 PolarHBondContact O-N 3.07Å; N122-V126 VanDerWaalsContact O-N 3.09Å
123E62.6Low66.1Low172 Ų17267.9 Ų67.980%0.80433%0.334SS*.Hα-helixtrans-52.6-39.7-177.9-66.7-177.1172.500111.7Q125 V126E123-Q125 PolarHBondContact O-N 2.6Å; E123-V126 PolarHBondContact O-N 2.75Å
124D62.5Low66.6Low137 Ų13771.5 Ų71.573%0.73336%0.364SS*.Hα-helixtrans-62.3-23.9177.3-60.9-32.5000114N122N122-D124 PolarHBondContact O-N 3.47Å
125Q67Low67.1Low8 Ų876.8 Ų76.84%0.03738%0.381CS..Hα-helixtrans-105.3-12.2-179.1-62.3-164.1-3.800113.2L78 P79 S119 N122 E123 E127 F128 Y129L78-Q125 HydrophobicContact CD2-CG 4.49Å; P79-Q125 PolarHBondContact O-NE2 3.18Å; S119-Q125 VanDerWaalsContact C-OE1 3.24Å; S119-Q125 VanDerWaalsContact O-CB 3.3Å; S119-Q125 WeakPolarHBondContact O-CB 3.36Å; S119-Q125 PolarHBondContact O-OE1 2.9Å; S119-Q125 PolarHBondContact OG-OE1 3.38Å; N122-Q125 PolarHBondContact O-N 2.83Å; E123-Q125 PolarHBondContact O-N 2.6Å; Q125-E127 PolarHBondContact O-N 3.09Å; Q125-F128 WeakPolarHBondContact O-CB 3.42Å; Q125-F128 PolarHBondContact O-N 3.13Å; Q125-Y129 HydrophobicContact CB-CE2 4.41Å; Q125-Y129 VanDerWaalsContact O-CD2 3.3Å; Q125-Y129 WeakPolarHBondContact O-CD2 3.19Å; Q125-Y129 PolarHBondContact O-N 3.49Å; Q125-Y129 VanDerWaalsContact O-N 3.11Å
126V68.5Low67.9Low55 Ų5584.1 Ų84.133%0.33341%0.408SS..Hα-helixtrans-56.8-42.9176.4170.70000110.1N122 E123 F128 Y129 Q130N122-V126 WeakPolarHBondContact O-CG2 3.1Å; N122-V126 PolarHBondContact O-N 3.07Å; N122-V126 VanDerWaalsContact O-N 3.09Å; E123-V126 PolarHBondContact O-N 2.75Å; V126-F128 VanDerWaalsContact C-N 3.32Å; V126-F128 PolarHBondContact O-N 3.24Å; V126-Y129 PolarHBondContact O-N 3.32Å; V126-Q130 HydrophobicContact CG1-CG 4.25Å; V126-Q130 WeakPolarHBondContact O-CB 3.36Å; V126-Q130 WeakPolarHBondContact O-CG 3.22Å; V126-Q130 PolarHBondContact O-N 2.81Å
127E69.7Low69.1Low127 Ų12784 Ų8459%0.59340%0.404SS*.Hα-helixtrans-60.4-40.4176.3-163.8-163.615100111.9Q125 Y129 Q130 N131Q125-E127 PolarHBondContact O-N 3.09Å; E127-Y129 PolarHBondContact O-N 3.4Å; E127-Q130 PolarHBondContact O-N 3.04Å; E127-N131 WeakPolarHBondContact O-CB 3.39Å; E127-N131 PolarHBondContact O-N 3.28Å; E127-N131 PolarHBondContact O-ND2 2.82Å; E127-N131 PolarHBondContact OE1-ND2 2.87Å
128F74.3Confident70.5Confident24 Ų2482.3 Ų82.311%0.10540%0.399CS..Hα-helixtrans-59.1-49.3174.7161-93.5000111.4V59 I76 L78 Q125 V126 Q130 N131 L132V59-F128 HydrophobicContact CG1-CZ 4.1Å; V59-F128 HydrophobicContact CG2-CE2 4.43Å; V59-F128 HydrophobicContact CG2-CZ 4.08Å; I76-F128 HydrophobicContact CB-CE2 4.25Å; I76-F128 HydrophobicContact CG2-CD2 3.67Å; I76-F128 HydrophobicContact CG2-CE2 3.44Å; I76-F128 VanDerWaalsContact CG2-CE2 3.44Å; L78-F128 HydrophobicContact CD1-CD1 3.87Å; L78-F128 HydrophobicContact CD1-CD2 4.24Å; L78-F128 HydrophobicContact CD1-CE1 3.61Å; L78-F128 HydrophobicContact CD1-CE2 3.98Å; L78-F128 HydrophobicContact CD1-CG 4.2Å; L78-F128 HydrophobicContact CD1-CZ 3.67Å; L78-F128 HydrophobicContact CD2-CB 3.85Å; L78-F128 HydrophobicContact CD2-CD1 3.94Å; L78-F128 HydrophobicContact CD2-CD2 3.72Å; L78-F128 HydrophobicContact CD2-CE1 4.48Å; L78-F128 HydrophobicContact CD2-CE2 4.25Å; L78-F128 HydrophobicContact CD2-CG 3.55Å; L78-F128 HydrophobicContact CG-CD1 4.46Å; L78-F128 HydrophobicContact CG-CD2 4.17Å; L78-F128 HydrophobicContact CG-CE2 4.21Å; L78-F128 HydrophobicContact CG-CG 4.31Å; L78-F128 HydrophobicContact CG-CZ 4.4Å; Q125-F128 WeakPolarHBondContact O-CB 3.42Å; Q125-F128 PolarHBondContact O-N 3.13Å; V126-F128 VanDerWaalsContact C-N 3.32Å; V126-F128 PolarHBondContact O-N 3.24Å; F128-Q130 VanDerWaalsContact C-N 3.32Å; F128-Q130 PolarHBondContact O-N 3.23Å; F128-N131 PolarHBondContact O-N 3.22Å; F128-L132 HydrophobicContact CE1-CD2 4.24Å; F128-L132 HydrophobicContact CE2-CD1 4.2Å; F128-L132 HydrophobicContact CZ-CD1 3.93Å; F128-L132 HydrophobicContact CZ-CD2 4.2Å; F128-L132 HydrophobicContact CZ-CG 4.5Å; F128-L132 VanDerWaalsContact O-CB 3.31Å; F128-L132 WeakPolarHBondContact O-CB 3.15Å; F128-L132 PolarHBondContact O-N 2.9Å
129Y71.6Confident71.8Confident22 Ų2273.8 Ų73.89%0.08637%0.367CS..Hα-helixtrans-68-33-179.7-75.3-79.6000111.9R120 Q125 V126 E127 L132 T133 T149R120-Y129 VanDerWaalsContact CA-CE2 3.49Å; R120-Y129 HydrophobicContact CB-CD2 4.45Å; R120-Y129 HydrophobicContact CB-CE2 3.85Å; R120-Y129 HydrophobicContact CG-CD1 4.32Å; R120-Y129 HydrophobicContact CG-CD2 3.93Å; R120-Y129 HydrophobicContact CG-CE1 4.06Å; R120-Y129 HydrophobicContact CG-CE2 3.72Å; R120-Y129 HydrophobicContact CG-CG 4.25Å; Q125-Y129 HydrophobicContact CB-CE2 4.41Å; Q125-Y129 VanDerWaalsContact O-CD2 3.3Å; Q125-Y129 WeakPolarHBondContact O-CD2 3.19Å; Q125-Y129 PolarHBondContact O-N 3.49Å; Q125-Y129 VanDerWaalsContact O-N 3.11Å; V126-Y129 PolarHBondContact O-N 3.32Å; E127-Y129 PolarHBondContact O-N 3.4Å; Y129-L132 HydrophobicContact CD1-CD2 4.46Å; Y129-L132 PolarHBondContact O-N 2.91Å; Y129-T133 WeakPolarHBondContact O-CB 3.46Å; Y129-T133 WeakPolarHBondContact O-CG2 3.35Å; Y129-T133 PolarHBondContact O-N 3.46Å; Y129-T133 PolarHBondContact O-OG1 3.34Å; Y129-T149 HydrophobicContact CE1-CG2 4.24Å
130Q72.3Confident73.2Confident118 Ų11873.9 Ų73.955%0.55137%0.366SS*.Hα-helixtrans-64.1-46.6171-73.8176.5-7.600111.4V126 E127 F128 L132 T133 A134V126-Q130 HydrophobicContact CG1-CG 4.25Å; V126-Q130 WeakPolarHBondContact O-CB 3.36Å; V126-Q130 WeakPolarHBondContact O-CG 3.22Å; V126-Q130 PolarHBondContact O-N 2.81Å; E127-Q130 PolarHBondContact O-N 3.04Å; F128-Q130 VanDerWaalsContact C-N 3.32Å; F128-Q130 PolarHBondContact O-N 3.23Å; Q130-L132 VanDerWaalsContact C-N 3.33Å; Q130-L132 PolarHBondContact O-N 3.24Å; Q130-T133 WeakPolarHBondContact CA-OG1 3.45Å; Q130-T133 PolarHBondContact O-N 2.88Å; Q130-T133 PolarHBondContact O-OG1 2.87Å; Q130-A134 VanDerWaalsContact O-CB 3.22Å; Q130-A134 WeakPolarHBondContact O-CB 3.46Å; Q130-A134 PolarHBondContact O-N 2.87Å
131N71Confident74.8Confident83 Ų8371.1 Ų71.144%0.44436%0.356SS..Hα-helixtrans-64.8-37.3176-79.2-30.7000112.3E127 F128 A134 R135E127-N131 WeakPolarHBondContact O-CB 3.39Å; E127-N131 PolarHBondContact O-N 3.28Å; E127-N131 PolarHBondContact O-ND2 2.82Å; E127-N131 PolarHBondContact OE1-ND2 2.87Å; F128-N131 PolarHBondContact O-N 3.22Å; N131-A134 PolarHBondContact O-N 3.35Å; N131-R135 WeakPolarHBondContact O-CG 3.42Å; N131-R135 PolarHBondContact O-N 3.33Å
132L74.3Confident76Confident14 Ų1465.7 Ų65.77%0.07333%0.331CS..Hα-helixtrans-61.6-45175.6-161.875.8000111.3L28 M30 F128 Y129 Q130 W137L28-L132 HydrophobicContact CD2-CD1 3.43Å; L28-L132 VanDerWaalsContact CD2-CD1 3.43Å; L28-L132 HydrophobicContact CD2-CD2 4.43Å; L28-L132 HydrophobicContact CD2-CG 4.17Å; M30-L132 HydrophobicContact CE-CD2 3.74Å; F128-L132 HydrophobicContact CE1-CD2 4.24Å; F128-L132 HydrophobicContact CE2-CD1 4.2Å; F128-L132 HydrophobicContact CZ-CD1 3.93Å; F128-L132 HydrophobicContact CZ-CD2 4.2Å; F128-L132 HydrophobicContact CZ-CG 4.5Å; F128-L132 VanDerWaalsContact O-CB 3.31Å; F128-L132 WeakPolarHBondContact O-CB 3.15Å; F128-L132 PolarHBondContact O-N 2.9Å; Y129-L132 HydrophobicContact CD1-CD2 4.46Å; Y129-L132 PolarHBondContact O-N 2.91Å; Q130-L132 VanDerWaalsContact C-N 3.33Å; Q130-L132 PolarHBondContact O-N 3.24Å; L132-W137 HydrophobicContact CD1-CZ2 4.25Å; L132-W137 PolarHBondContact O-NE1 2.91Å
133T70.9Confident76.8Confident76 Ų7663.1 Ų63.147%0.46632%0.318SS..Hα-helixtrans-78.4-27.3-179.750.70000113.1Y129 Q130 R135Y129-T133 WeakPolarHBondContact O-CB 3.46Å; Y129-T133 WeakPolarHBondContact O-CG2 3.35Å; Y129-T133 PolarHBondContact O-N 3.46Å; Y129-T133 PolarHBondContact O-OG1 3.34Å; Q130-T133 WeakPolarHBondContact CA-OG1 3.45Å; Q130-T133 PolarHBondContact O-N 2.88Å; Q130-T133 PolarHBondContact O-OG1 2.87Å; T133-R135 VanDerWaalsContact C-N 3.29Å; T133-R135 PolarHBondContact O-N 3.49Å
134A72.8Confident77.2Confident83 Ų8355.5 Ų55.569%0.68629%0.285SS*.Hα-helixtrans-68.3-27.817400000112.4Q130 N131Q130-A134 VanDerWaalsContact O-CB 3.22Å; Q130-A134 WeakPolarHBondContact O-CB 3.46Å; Q130-A134 PolarHBondContact O-N 2.87Å; N131-A134 PolarHBondContact O-N 3.35Å
135R76Confident77.1Confident138 Ų13849.4 Ų49.452%0.52125%0.253SS..SBendtrans-81135.7175.5-70.6-177-177-163.42.1111.2N131 T133 W137N131-R135 WeakPolarHBondContact O-CG 3.42Å; N131-R135 PolarHBondContact O-N 3.33Å; T133-R135 VanDerWaalsContact C-N 3.29Å; T133-R135 PolarHBondContact O-N 3.49Å; R135-W137 HydrophobicContact CB-CZ2 4.23Å; R135-W137 PolarHBondContact O-N 2.82Å
136K82Confident76.6Confident183 Ų18350.9 Ų50.980%0.79626%0.259SS*.  trans-84.1100.1171.1-171177.7-178.4177.40109.8
137W86.9Confident75.9Confident15 Ų1548.5 Ų48.56%0.05724%0.244CC..  trans-81.2138.3171.4-57.598.7000110.3H26 L28 L132 R135 L140H26-W137 HydrophobicContact CB-CE3 4.04Å; H26-W137 HydrophobicContact CB-CZ3 4.43Å; L28-W137 HydrophobicContact CB-CD2 3.8Å; L28-W137 HydrophobicContact CB-CE3 3.58Å; L28-W137 HydrophobicContact CB-CG 4.48Å; L28-W137 HydrophobicContact CB-CH2 4.07Å; L28-W137 HydrophobicContact CB-CZ2 4.28Å; L28-W137 HydrophobicContact CB-CZ3 3.72Å; L28-W137 HydrophobicContact CD1-CH2 3.74Å; L28-W137 HydrophobicContact CD1-CZ2 3.99Å; L28-W137 HydrophobicContact CD1-CZ3 4.17Å; L28-W137 HydrophobicContact CD2-CD2 4.37Å; L28-W137 HydrophobicContact CD2-CZ2 4.05Å; L28-W137 HydrophobicContact CG-CH2 4.32Å; L28-W137 HydrophobicContact CG-CZ2 4.33Å; L28-W137 HydrophobicContact CG-CZ3 4.45Å; L132-W137 HydrophobicContact CD1-CZ2 4.25Å; L132-W137 PolarHBondContact O-NE1 2.91Å; R135-W137 HydrophobicContact CB-CZ2 4.23Å; R135-W137 PolarHBondContact O-N 2.82Å; W137-L140 HydrophobicContact CB-CD2 3.74Å; W137-L140 HydrophobicContact CG-CD2 3.79Å
138D89.3Confident75.1Confident49 Ų4943.4 Ų43.426%0.26222%0.224SC..SBendtrans-79.8-29.4171.2-69.1-84.3000111.1K25 H26 L448K25-D138 WeakPolarHBondContact CA-OD2 3.08Å; K25-D138 HydrophobicContact CB-CB 3.97Å; K25-D138 HydrophobicContact CD-CB 4.19Å; K25-D138 WeakPolarHBondContact CD-OD1 3.47Å; K25-D138 HydrophobicContact CG-CB 4.46Å; K25-D138 IonicContact NZ-OD1 3.25Å; K25-D138 PolarHBondContact NZ-OD1 3.33Å; H26-D138 PolarHBondContact N-OD2 2.92Å; H26-D138 PolarHBondContact O-N 3.46Å; D138-L448 HydrophobicContact CB-CD2 4.33Å
139L90.8Very high73.8Confident1 Ų143.3 Ų43.31%0.00523%0.225CC..EExtended strand (participates in β ladder)trans-156.4136.2-178.9-177.767.3000112.1H26 I27 L28 I141 A155 I157 I444 Y447 L448H26-L139 PolarHBondContact O-N 3.37Å; I27-L139 WeakPolarHBondContact CA-O 3.44Å; I27-L139 HydrophobicContact CG1-CB 4.47Å; I27-L139 HydrophobicContact CG2-CD2 4.48Å; L28-L139 PolarHBondContact N-O 2.87Å; L28-L139 VanDerWaalsContact N-O 3.08Å; L139-I141 HydrophobicContact CD2-CD1 4.26Å; L139-I141 HydrophobicContact CD2-CG1 4.3Å; L139-I141 HydrophobicContact CG-CG1 4.29Å; L139-A155 HydrophobicContact CD1-CB 4.14Å; L139-I157 HydrophobicContact CD1-CD1 4.25Å; L139-I157 HydrophobicContact CD1-CG1 4.14Å; L139-I157 HydrophobicContact CD2-CD1 3.89Å; L139-I444 HydrophobicContact CD2-CG2 3.6Å; L139-Y447 HydrophobicContact CD1-CD1 4.25Å; L139-Y447 HydrophobicContact CD1-CE1 4.1Å; L139-L448 HydrophobicContact CB-CD2 4.18Å; L139-L448 HydrophobicContact CD2-CD2 4.49Å
140L89.2Confident72.7Confident14 Ų1448.8 Ų48.87%0.07326%0.256CS..EExtended strand (participates in β ladder)trans-103.7142170.9-53.9178.8000110.7L28 W137 P142 A155 W156 I157L28-L140 HydrophobicContact CB-CD2 3.97Å; L28-L140 HydrophobicContact CD2-CD2 4.07Å; W137-L140 HydrophobicContact CB-CD2 3.74Å; W137-L140 HydrophobicContact CG-CD2 3.79Å; L140-P142 VanDerWaalsContact C-CD 3.41Å; L140-P142 WeakPolarHBondContact O-CD 3.46Å; L140-A155 PolarHBondContact N-O 3.37Å; L140-W156 HydrophobicContact CB-CB 3.95Å; L140-W156 CarbonylContact O-C 3.57Å; L140-W156 WeakPolarHBondContact O-CA 3.48Å; L140-W156 WeakPolarHBondContact O-CB 3.34Å; L140-I157 PolarHBondContact O-N 3.39Å
141I91.3Very high71.7Confident0 Ų044.8 Ų44.80%024%0.24CC..EExtended strand (participates in β ladder)trans-127.374175.8-52.1-178.9000109.6I27 L28 F29 M30 L49 L139 I157 Y159 I444I27-I141 HydrophobicContact CG2-CD1 3.66Å; I27-I141 HydrophobicContact CG2-CG1 4.07Å; L28-I141 PolarHBondContact O-N 3.12Å; F29-I141 HydrophobicContact CD1-CB 3.97Å; F29-I141 HydrophobicContact CD1-CD1 4.44Å; F29-I141 HydrophobicContact CD1-CG2 3.88Å; F29-I141 HydrophobicContact CD2-CD1 4.49Å; F29-I141 HydrophobicContact CE1-CB 4.13Å; F29-I141 HydrophobicContact CE1-CD1 3.85Å; F29-I141 HydrophobicContact CE1-CG2 3.82Å; F29-I141 HydrophobicContact CE2-CD1 3.89Å; F29-I141 HydrophobicContact CG-CB 4.32Å; F29-I141 HydrophobicContact CZ-CD1 3.54Å; M30-I141 PolarHBondContact N-O 3.27Å; L49-I141 HydrophobicContact CD1-CD1 4.35Å; L139-I141 HydrophobicContact CD2-CD1 4.26Å; L139-I141 HydrophobicContact CD2-CG1 4.3Å; L139-I141 HydrophobicContact CG-CG1 4.29Å; I141-I157 WeakPolarHBondContact CA-O 3.46Å; I141-I157 HydrophobicContact CG1-CB 4.42Å; I141-Y159 HydrophobicContact CG2-CD2 3.9Å; I141-Y159 HydrophobicContact CG2-CG 4.29Å; I141-I444 HydrophobicContact CD1-CD1 3.92Å
142P86Confident70.9Confident3 Ų351 Ų512%0.01926%0.263CS..EExtended strand (participates in β ladder)trans-78.7147.6175.730.9-34.5000112.9M30 L140 W156 I157 Y159 F226M30-P142 HydrophobicContact CB-CB 4.28Å; M30-P142 WeakPolarHBondContact O-CA 3.22Å; L140-P142 VanDerWaalsContact C-CD 3.41Å; L140-P142 WeakPolarHBondContact O-CD 3.46Å; P142-W156 HydrophobicContact CG-CB 4.44Å; P142-I157 WeakPolarHBondContact CD-O 3.36Å; P142-Y159 PolarHBondContact O-N 3.4Å; P142-F226 HydrophobicContact CB-CE2 4.4Å; P142-F226 HydrophobicContact CB-CZ 4.28Å; P142-F226 HydrophobicContact CG-CE2 3.56Å; P142-F226 HydrophobicContact CG-CZ 3.67Å
143S83.2Confident70.4Confident4 Ų454.4 Ų54.43%0.02830%0.302CS..SBendtrans-99102.6162.6175.90000109M30 A32 M42 Y159 T161M30-S143 PolarHBondContact O-N 3.38Å; A32-S143 WeakPolarHBondContact CB-O 3.3Å; A32-S143 WeakPolarHBondContact CB-OG 3.47Å; M42-S143 VanDerWaalsContact CE-CB 3.5Å; S143-Y159 WeakPolarHBondContact CA-O 3.31Å; S143-Y159 WeakPolarHBondContact CB-O 3.24Å; S143-Y159 PolarHBondContact OG-O 3.34Å; S143-Y159 VanDerWaalsContact OG-O 3.12Å; S143-T161 PolarHBondContact OG-N 2.88Å; S143-T161 PolarHBondContact OG-OG1 3.31Å
144G71.2Confident70.7Confident11 Ų1153.5 Ų53.511%0.11329%0.292CS..SBendtrans74.1173.5-178.900000115H146G144-H146 VanDerWaalsContact C-N 3.27Å; G144-H146 PolarHBondContact O-N 3.48Å
145L60.7Low71.3Confident10 Ų1050.4 Ų50.45%0.05227%0.266CS..G310 helixtrans-68.4-19.5-170.6-171.973.7000114.5Y147 A148 F214 L218 I223 F226L145-Y147 PolarHBondContact O-N 2.94Å; L145-A148 HydrophobicContact CD1-CB 4.26Å; L145-A148 PolarHBondContact O-N 3.3Å; L145-A148 VanDerWaalsContact O-N 3.12Å; L145-F214 HydrophobicContact CD2-CE1 4.26Å; L145-L218 HydrophobicContact CD2-CB 4.25Å; L145-L218 HydrophobicContact CD2-CD1 3.83Å; L145-I223 HydrophobicContact CD1-CG1 4.4Å; L145-I223 HydrophobicContact CD2-CB 4.13Å; L145-I223 HydrophobicContact CD2-CD1 3.37Å; L145-I223 HydrophobicContact CD2-CG1 3.37Å; L145-I223 HydrophobicContact CD2-CG2 4.1Å; L145-F226 HydrophobicContact CD1-CB 3.69Å; L145-F226 HydrophobicContact CD1-CD1 4.1Å; L145-F226 HydrophobicContact CD1-CG 3.84Å
146H56.7Low71.9Confident38 Ų3844.4 Ų44.418%0.17624%0.244CC..G310 helixtrans-52.5-20.6-171.9-61.5-58.4000114.1S113 R120 G144 F214S113-H146 PolarHBondContact OG-CE1 3.14Å; R120-H146 PolarHBondContact NH2-O 3.09Å; G144-H146 VanDerWaalsContact C-N 3.27Å; G144-H146 PolarHBondContact O-N 3.48Å; H146-F214 AromaticContact CE1-CZ 3.82Å
147Y54.2Low72.3Confident6 Ų635.7 Ų35.72%0.02421%0.206CC..G310 helixtrans-122.6-2.9-175.3-55.1-60.1000116.1M30 P31 M33 F61 L145 T149M30-Y147 HydrophobicContact CB-CD2 4.08Å; M30-Y147 HydrophobicContact CB-CG 4.11Å; M30-Y147 HydrophobicContact CE-CG 4.27Å; P31-Y147 WeakPolarHBondContact O-CE2 3.43Å; P31-Y147 PolarHBondContact O-OH 2.76Å; M33-Y147 PolarHBondContact N-OH 2.66Å; F61-Y147 HydrophobicContact CD2-CE1 4.18Å; F61-Y147 WeakPolarHBondContact CD2-OH 3.38Å; F61-Y147 HydrophobicContact CE2-CD1 4.15Å; F61-Y147 AromaticContact CE2-CE1 3.19Å; F61-Y147 HydrophobicContact CE2-CE1 3.19Å; F61-Y147 AromaticContact CE2-CZ 3.48Å; F61-Y147 VanDerWaalsContact CE2-CZ 3.48Å; F61-Y147 VanDerWaalsContact CE2-OH 3.23Å; F61-Y147 WeakPolarHBondContact CE2-OH 3.45Å; F61-Y147 HydrophobicContact CZ-CD1 4.39Å; F61-Y147 AromaticContact CZ-CE1 3.52Å; F61-Y147 HydrophobicContact CZ-CE1 3.52Å; L145-Y147 PolarHBondContact O-N 2.94Å; Y147-T149 PolarHBondContact O-N 3.1Å; Y147-T149 PolarHBondContact O-OG1 3.23Å
148A52.6Low72.3Confident20 Ų2035 Ų3517%0.16520%0.203CC..  trans-73.768.7177.300000110.2L145 T151 F226L145-A148 HydrophobicContact CD1-CB 4.26Å; L145-A148 PolarHBondContact O-N 3.3Å; L145-A148 VanDerWaalsContact O-N 3.12Å; A148-T151 HydrophobicContact CB-CG2 4.49Å; A148-F226 HydrophobicContact CB-CD2 3.27Å; A148-F226 HydrophobicContact CB-CE2 3.47Å; A148-F226 VanDerWaalsContact CB-CE2 3.47Å; A148-F226 HydrophobicContact CB-CG 4.11Å; A148-F226 HydrophobicContact CB-CZ 4.44Å
149T46.5Very low72.3Confident22 Ų2233 Ų3314%0.13519%0.192CC..  trans-88.8120.417640.10000108.4R120 Y129 Y147 T151R120-T149 VanDerWaalsContact NH1-CG2 3.3Å; Y129-T149 HydrophobicContact CE1-CG2 4.24Å; Y147-T149 PolarHBondContact O-N 3.1Å; Y147-T149 PolarHBondContact O-OG1 3.23Å; T149-T151 PolarHBondContact O-N 3.07Å
150N50Low72Confident137 Ų13733.1 Ų33.173%0.73319%0.193SC*.  trans57.346.8164.7-62.2-18.1000116.2K152N150-K152 PolarHBondContact O-N 3.05Å
151T51.1Low71.7Confident33 Ų3332.6 Ų32.620%0.20219%0.191CC..  trans-67.220.8177.152.50000115.7A148 T149 G153 Q154 W156A148-T151 HydrophobicContact CB-CG2 4.49Å; T149-T151 PolarHBondContact O-N 3.07Å; T151-G153 PolarHBondContact O-N 3.2Å; T151-Q154 PolarHBondContact O-N 2.93Å; T151-W156 HydrophobicContact CG2-CE3 3.97Å; T151-W156 HydrophobicContact CG2-CZ3 4.2Å
152K53.3Low70.9Confident213 Ų21335 Ų3593%0.92621%0.205SC*.THydrogen-bonded Turntrans-62.4103.5177.1-79.8-168.8179.2-179.10109.8N150N150-K152 PolarHBondContact O-N 3.05Å
153G64.4Low70.4Confident87 Ų8735.8 Ų35.890%0.89721%0.209SC*.THydrogen-bonded Turntrans86.82.617500000116.8T151T151-G153 PolarHBondContact O-N 3.2Å
154Q77.1Confident70.1Confident57 Ų5737.2 Ų37.227%0.26622%0.216SC..  trans-103.9143.5176.9-67.7-175.71100111.5T151 W156T151-Q154 PolarHBondContact O-N 2.93Å; Q154-W156 VanDerWaalsContact O-CE3 3.3Å
155A85.4Confident70.3Confident17 Ų1738.5 Ų38.514%0.1422%0.22CC..  trans-85145.2177.400000111.6L139 L140 V231 Y447L139-A155 HydrophobicContact CD1-CB 4.14Å; L140-A155 PolarHBondContact N-O 3.37Å; A155-V231 HydrophobicContact CB-CG2 4.13Å; A155-Y447 HydrophobicContact CB-CE1 3.66Å; A155-Y447 WeakPolarHBondContact CB-OH 3.39Å
156W87.7Confident71Confident13 Ų1338.4 Ų38.45%0.04922%0.219CC..BIsolated β-bridgetrans-139.7156.3173.270.794.7000113.3L140 P142 T151 Q154 D225 F226 N229 V231L140-W156 HydrophobicContact CB-CB 3.95Å; L140-W156 CarbonylContact O-C 3.57Å; L140-W156 WeakPolarHBondContact O-CA 3.48Å; L140-W156 WeakPolarHBondContact O-CB 3.34Å; P142-W156 HydrophobicContact CG-CB 4.44Å; T151-W156 HydrophobicContact CG2-CE3 3.97Å; T151-W156 HydrophobicContact CG2-CZ3 4.2Å; Q154-W156 VanDerWaalsContact O-CE3 3.3Å; W156-D225 WeakPolarHBondContact CZ2-O 3.48Å; W156-F226 AromaticContact CD1-CD2 3.92Å; W156-F226 AromaticContact CD1-CE2 3.53Å; W156-F226 AromaticContact CE2-CD2 3.95Å; W156-F226 VanDerWaalsContact CE2-O 3.27Å; W156-F226 HydrophobicContact CG-CE2 4.27Å; W156-F226 HydrophobicContact CZ2-CD2 4.45Å; W156-F226 VanDerWaalsContact CZ2-O 3.27Å; W156-F226 WeakPolarHBondContact CZ2-O 3.45Å; W156-F226 AromaticContact NE1-CD2 3.46Å; W156-F226 AromaticContact NE1-CE2 3.55Å; W156-F226 PolarHBondContact NE1-O 3.2Å; W156-N229 HydrophobicContact CH2-CB 3.54Å; W156-N229 HydrophobicContact CZ2-CB 3.68Å; W156-V231 WeakPolarHBondContact O-CB 3.39Å; W156-V231 WeakPolarHBondContact O-CG2 3.44Å; W156-V231 PolarHBondContact O-N 3.13Å
157I90.3Very high71.8Confident0 Ų036.7 Ų36.70%021%0.211CC..  trans-117.3122.7169.1-70.4169.5000107.7L139 L140 I141 P142 Y159 V231 Y232 I234 I444L139-I157 HydrophobicContact CD1-CD1 4.25Å; L139-I157 HydrophobicContact CD1-CG1 4.14Å; L139-I157 HydrophobicContact CD2-CD1 3.89Å; L140-I157 PolarHBondContact O-N 3.39Å; I141-I157 WeakPolarHBondContact CA-O 3.46Å; I141-I157 HydrophobicContact CG1-CB 4.42Å; P142-I157 WeakPolarHBondContact CD-O 3.36Å; I157-Y159 PolarHBondContact O-N 3.5Å; I157-V231 HydrophobicContact CG1-CB 4.04Å; I157-V231 HydrophobicContact CG1-CG1 4.35Å; I157-Y232 WeakPolarHBondContact CA-O 3.47Å; I157-Y232 HydrophobicContact CD1-CD2 3.77Å; I157-Y232 HydrophobicContact CG1-CD2 4.11Å; I157-I234 HydrophobicContact CG2-CD1 3.6Å; I157-I234 HydrophobicContact CG2-CG1 3.86Å; I157-I444 HydrophobicContact CD1-CB 4.43Å; I157-I444 HydrophobicContact CD1-CD1 4.44Å; I157-I444 HydrophobicContact CD1-CG1 3.62Å
158D86.7Confident72.9Confident0 Ų036.9 Ų36.90%021%0.213CC..EExtended strand (participates in β ladder)trans-79.8108.6178.4172.428000110.2R172 F226 Y227 A230 Y232 S233 I234D158-R172 IonicContact OD1-CZ 2.9Å; D158-R172 IonicContact OD1-NE 3.5Å; D158-R172 IonicContact OD1-NH2 3.87Å; D158-R172 PolarHBondContact OD1-NH2 3.13Å; D158-R172 WeakPolarHBondContact OD2-CD 3.43Å; D158-R172 IonicContact OD2-CZ 2.65Å; D158-R172 IonicContact OD2-NE 2.68Å; D158-R172 PolarHBondContact OD2-NE 3.19Å; D158-R172 IonicContact OD2-NH2 3.69Å; D158-R172 PolarHBondContact OD2-NH2 3.35Å; D158-F226 HydrophobicContact CB-CE1 4.35Å; D158-F226 HydrophobicContact CB-CZ 4.29Å; D158-Y227 WeakPolarHBondContact OD2-CD1 3.33Å; D158-Y227 WeakPolarHBondContact OD2-CE1 3.24Å; D158-A230 HydrophobicContact CB-CB 4.09Å; D158-Y232 PolarHBondContact N-O 3.46Å; D158-S233 CarbonylContact O-C 3.58Å; D158-S233 VanDerWaalsContact O-CA 3.31Å; D158-S233 WeakPolarHBondContact O-CA 3.34Å; D158-I234 PolarHBondContact O-N 3.22Å
159Y89.1Confident74.1Confident7 Ų736.6 Ų36.63%0.02721%0.207CC..EExtended strand (participates in β ladder)trans-10796.9-178.7-173-5.3000110.8F29 S41 M42 L45 I141 P142 S143 I157 T161 I234F29-Y159 HydrophobicContact CE1-CD2 4.25Å; F29-Y159 HydrophobicContact CE1-CE2 4.45Å; S41-Y159 PolarHBondContact O-OH 3.01Å; M42-Y159 HydrophobicContact CB-CE2 4.39Å; M42-Y159 HydrophobicContact CE-CD2 3.9Å; M42-Y159 HydrophobicContact CE-CG 3.89Å; M42-Y159 HydrophobicContact CG-CD2 4.03Å; M42-Y159 HydrophobicContact CG-CE2 3.88Å; L45-Y159 HydrophobicContact CB-CE2 4.47Å; L45-Y159 HydrophobicContact CD2-CD2 4.08Å; L45-Y159 HydrophobicContact CD2-CE2 3.67Å; I141-Y159 HydrophobicContact CG2-CD2 3.9Å; I141-Y159 HydrophobicContact CG2-CG 4.29Å; P142-Y159 PolarHBondContact O-N 3.4Å; S143-Y159 WeakPolarHBondContact CA-O 3.31Å; S143-Y159 WeakPolarHBondContact CB-O 3.24Å; S143-Y159 PolarHBondContact OG-O 3.34Å; S143-Y159 VanDerWaalsContact OG-O 3.12Å; I157-Y159 PolarHBondContact O-N 3.5Å; Y159-T161 PolarHBondContact O-N 2.8Å; Y159-T161 VanDerWaalsContact O-N 3.16Å; Y159-I234 HydrophobicContact CD1-CB 3.82Å; Y159-I234 HydrophobicContact CD1-CG2 3.59Å; Y159-I234 HydrophobicContact CE1-CB 4.4Å; Y159-I234 HydrophobicContact CE1-CG2 3.65Å; Y159-I234 HydrophobicContact CG-CB 4.06Å; Y159-I234 HydrophobicContact CG-CG2 4.13Å
160S85.9Confident75.5Confident4 Ų438 Ų383%0.02821%0.212CC..  trans-71.3104.8173.3-158.50000111.6T162 R172 I234 S236S160-T162 WeakPolarHBondContact CB-O 3.22Å; S160-T162 PolarHBondContact O-N 3.11Å; S160-T162 PolarHBondContact OG-O 2.97Å; S160-R172 VanDerWaalsContact CB-NH1 3.31Å; S160-R172 PolarHBondContact OG-NH1 3.12Å; S160-I234 WeakPolarHBondContact CB-O 3.31Å; S160-I234 PolarHBondContact N-O 3.1Å; S160-S236 WeakPolarHBondContact O-CB 3.08Å; S160-S236 PolarHBondContact O-N 3.08Å
161T81.5Confident76.7Confident3 Ų332.5 Ų32.52%0.01818%0.183CC..SBendtrans-76.6-6.1171.149.50000113.3H38 M42 S143 Y159 S236H38-T161 PolarHBondContact CE1-OG1 3.25Å; H38-T161 PolarHBondContact ND1-OG1 3.32Å; M42-T161 HydrophobicContact CE-CG2 3.72Å; M42-T161 HydrophobicContact CG-CG2 3.78Å; M42-T161 HydrophobicContact SD-CG2 4.38Å; S143-T161 PolarHBondContact OG-N 2.88Å; S143-T161 PolarHBondContact OG-OG1 3.31Å; Y159-T161 PolarHBondContact O-N 2.8Å; Y159-T161 VanDerWaalsContact O-N 3.16Å; T161-S236 PolarHBondContact O-OG 2.88Å
162T76.3Confident77.8Confident50 Ų5031.5 Ų31.531%0.30718%0.175SC..SBendtrans-122.5-179.2175.259.90000110H38 S160H38-T162 VanDerWaalsContact CE1-CG2 3.41Å; H38-T162 WeakPolarHBondContact CE1-CG2 3.14Å; S160-T162 WeakPolarHBondContact CB-O 3.22Å; S160-T162 PolarHBondContact O-N 3.11Å; S160-T162 PolarHBondContact OG-O 2.97Å
163L74.2Confident78.8Confident19 Ų1921.6 Ų21.610%0.09913%0.133CC..  trans-50.4144.1172.8-60.5169.4000112.8L165 D378 R381L163-L165 PolarHBondContact O-N 3.25Å; L163-D378 HydrophobicContact CD1-CB 3.2Å; L163-D378 HydrophobicContact CG-CB 3.7Å; L163-R381 HydrophobicContact CD1-CB 4.11Å; L163-R381 HydrophobicContact CD1-CG 4.34Å
164M76.5Confident79.4Confident34 Ų3417.7 Ų17.717%0.1679%0.092CC..  trans-75110.2164.5-175.8176.8-66.400108.7R169 R172 A173 T251M164-R169 HydrophobicContact CG-CB 4.04Å; M164-R169 HydrophobicContact CG-CG 4.42Å; M164-R169 HydrophobicContact SD-CB 3.94Å; M164-R169 HydrophobicContact SD-CG 3.75Å; M164-R172 HydrophobicContact CE-CB 3.87Å; M164-R172 HydrophobicContact SD-CB 4.07Å; M164-A173 HydrophobicContact CE-CB 4.42Å; M164-A173 HydrophobicContact SD-CB 3.93Å; M164-T251 HydrophobicContact CE-CG2 3.68Å
165L75.5Confident79.4Confident38 Ų3820.3 Ų20.320%0.19911%0.105CC..  trans-65.4149.4176-64.4177.5000111L163 C167 I168 R169 M184L163-L165 PolarHBondContact O-N 3.25Å; L165-C167 VanDerWaalsContact C-N 3.34Å; L165-C167 PolarHBondContact O-N 2.73Å; L165-I168 HydrophobicContact CB-CD1 4.33Å; L165-I168 HydrophobicContact CB-CG1 4.39Å; L165-I168 HydrophobicContact CD1-CD1 4.27Å; L165-I168 PolarHBondContact O-N 3.17Å; L165-I168 VanDerWaalsContact O-N 3.11Å; L165-R169 WeakPolarHBondContact O-CB 3.31Å; L165-R169 PolarHBondContact O-N 2.89Å; L165-M184 HydrophobicContact CD2-CE 3.99Å
166Q76.6Confident79.3Confident9 Ų919.8 Ų19.84%0.04210%0.1CC..Hα-helixtrans-59.4-43-178.2166.6165.650.900112.4I168 R169 P178 E181 Y204Q166-I168 PolarHBondContact O-N 3.38Å; Q166-R169 PolarHBondContact O-N 3.01Å; Q166-P178 VanDerWaalsContact NE2-CA 3.32Å; Q166-E181 VanDerWaalsContact CA-OE1 3.28Å; Q166-E181 WeakPolarHBondContact CA-OE1 3.3Å; Q166-E181 VanDerWaalsContact CB-CD 3.49Å; Q166-E181 HydrophobicContact CB-CG 4.47Å; Q166-E181 WeakPolarHBondContact CB-OE1 3.23Å; Q166-E181 WeakPolarHBondContact CB-OE2 3.36Å; Q166-E181 WeakPolarHBondContact CG-OE2 3.36Å; Q166-E181 PolarHBondContact NE2-OE2 3.48Å; Q166-Y204 HydrophobicContact CG-CD2 3.7Å; Q166-Y204 HydrophobicContact CG-CE2 4.38Å
167C73.5Confident79.1Confident2 Ų220 Ų201%0.01410%0.102CC..Hα-helixtrans-65.5-26178.559.10000113.9L165 Q170 Q207L165-C167 VanDerWaalsContact C-N 3.34Å; L165-C167 PolarHBondContact O-N 2.73Å; C167-Q170 VanDerWaalsContact O-CG 3.28Å; C167-Q170 WeakPolarHBondContact O-CG 3.49Å; C167-Q170 PolarHBondContact O-NE2 3.24Å; C167-Q207 HydrophobicContact CB-CB 4.02Å
168I76.2Confident79Confident9 Ų920.8 Ų20.85%0.04611%0.107CC..Hα-helixtrans-93.7-25.7179.4-54.4174.2000110.5L165 Q166 Q170 L171 R172 W211 Y227L165-I168 HydrophobicContact CB-CD1 4.33Å; L165-I168 HydrophobicContact CB-CG1 4.39Å; L165-I168 HydrophobicContact CD1-CD1 4.27Å; L165-I168 PolarHBondContact O-N 3.17Å; L165-I168 VanDerWaalsContact O-N 3.11Å; Q166-I168 PolarHBondContact O-N 3.38Å; I168-Q170 PolarHBondContact O-N 3.2Å; I168-L171 CarbonylContact O-C 3.07Å; I168-L171 WeakPolarHBondContact O-CA 3.34Å; I168-L171 WeakPolarHBondContact O-CB 3.23Å; I168-L171 PolarHBondContact O-N 3.43Å; I168-R172 VanDerWaalsContact CG2-CD 3.41Å; I168-R172 HydrophobicContact CG2-CG 3.62Å; I168-R172 PolarHBondContact O-N 3.37Å; I168-W211 HydrophobicContact CD1-CH2 3.79Å; I168-W211 HydrophobicContact CD1-CZ2 4.21Å; I168-W211 HydrophobicContact CD1-CZ3 4.19Å; I168-W211 HydrophobicContact CG1-CH2 4.08Å; I168-W211 HydrophobicContact CG1-CZ2 4.01Å; I168-Y227 HydrophobicContact CD1-CE2 4.43Å; I168-Y227 HydrophobicContact CG2-CD1 3.59Å; I168-Y227 HydrophobicContact CG2-CD2 3.98Å; I168-Y227 HydrophobicContact CG2-CE1 3.58Å; I168-Y227 HydrophobicContact CG2-CE2 3.99Å; I168-Y227 HydrophobicContact CG2-CG 3.79Å
169R79Confident79Confident14 Ų1420.9 Ų20.95%0.05311%0.108CC..Hα-helixtrans-55.9-38.5179.2-174.4177.4-175.991.710.7112.8M164 L165 Q166 L171 R172 A173 P246M164-R169 HydrophobicContact CG-CB 4.04Å; M164-R169 HydrophobicContact CG-CG 4.42Å; M164-R169 HydrophobicContact SD-CB 3.94Å; M164-R169 HydrophobicContact SD-CG 3.75Å; L165-R169 WeakPolarHBondContact O-CB 3.31Å; L165-R169 PolarHBondContact O-N 2.89Å; Q166-R169 PolarHBondContact O-N 3.01Å; R169-L171 PolarHBondContact O-N 2.92Å; R169-R172 PolarHBondContact O-N 2.93Å; R169-A173 HydrophobicContact CG-CB 4.14Å; R169-A173 CarbonylContact O-C 3.54Å; R169-A173 WeakPolarHBondContact O-CA 3.48Å; R169-A173 WeakPolarHBondContact O-CB 3.33Å; R169-A173 PolarHBondContact O-N 3.17Å; R169-P246 PolarHBondContact NH2-O 3.31Å
170Q75.6Confident79Confident52 Ų5220.8 Ų20.824%0.24311%0.109CC..Hα-helixtrans-63.5-21175.567.3-173.5-4.500113.7C167 I168 H175 Q208C167-Q170 VanDerWaalsContact O-CG 3.28Å; C167-Q170 WeakPolarHBondContact O-CG 3.49Å; C167-Q170 PolarHBondContact O-NE2 3.24Å; I168-Q170 PolarHBondContact O-N 3.2Å; Q170-H175 HydrophobicContact CB-CB 4.36Å; Q170-Q208 VanDerWaalsContact NE2-NE2 3.1Å
171L75.6Confident79Confident21 Ų2121.1 Ų21.111%0.1111%0.109CC..Hα-helixtrans-98.2-38.2177.9-54.2175.8000112.1I168 R169 D224 Y227 T228 L462I168-L171 CarbonylContact O-C 3.07Å; I168-L171 WeakPolarHBondContact O-CA 3.34Å; I168-L171 WeakPolarHBondContact O-CB 3.23Å; I168-L171 PolarHBondContact O-N 3.43Å; R169-L171 PolarHBondContact O-N 2.92Å; L171-D224 WeakPolarHBondContact CD1-OD1 3.41Å; L171-Y227 HydrophobicContact CB-CG 4.43Å; L171-Y227 HydrophobicContact CD1-CD2 4.11Å; L171-Y227 HydrophobicContact CD1-CG 4.48Å; L171-T228 HydrophobicContact CB-CG2 4.42Å; L171-T228 HydrophobicContact CD2-CG2 4.16Å; L171-L462 HydrophobicContact CD2-CD2 4.15Å
172R73.9Confident79.2Confident12 Ų1221.3 Ų21.35%0.04511%0.111CC..Hα-helixtrans-83.9-25.7-176.7-81.3176.8-179.5-169.9-20.2114.7D158 S160 M164 I168 R169 Y227 T251D158-R172 IonicContact OD1-CZ 2.9Å; D158-R172 IonicContact OD1-NE 3.5Å; D158-R172 IonicContact OD1-NH2 3.87Å; D158-R172 PolarHBondContact OD1-NH2 3.13Å; D158-R172 WeakPolarHBondContact OD2-CD 3.43Å; D158-R172 IonicContact OD2-CZ 2.65Å; D158-R172 IonicContact OD2-NE 2.68Å; D158-R172 PolarHBondContact OD2-NE 3.19Å; D158-R172 IonicContact OD2-NH2 3.69Å; D158-R172 PolarHBondContact OD2-NH2 3.35Å; S160-R172 VanDerWaalsContact CB-NH1 3.31Å; S160-R172 PolarHBondContact OG-NH1 3.12Å; M164-R172 HydrophobicContact CE-CB 3.87Å; M164-R172 HydrophobicContact SD-CB 4.07Å; I168-R172 VanDerWaalsContact CG2-CD 3.41Å; I168-R172 HydrophobicContact CG2-CG 3.62Å; I168-R172 PolarHBondContact O-N 3.37Å; R169-R172 PolarHBondContact O-N 2.93Å; R172-Y227 HydrophobicContact CG-CD1 3.64Å; R172-Y227 HydrophobicContact CG-CE1 4.34Å; R172-Y227 HydrophobicContact CG-CG 4.33Å; R172-T251 PolarHBondContact O-OG1 3.37Å
173A73.6Confident79.5Confident6 Ų619.1 Ų19.15%0.0510%0.097CC..SBendtrans-145.3-122.6-16500000110.4M164 R169 T248 T251M164-A173 HydrophobicContact CE-CB 4.42Å; M164-A173 HydrophobicContact SD-CB 3.93Å; R169-A173 HydrophobicContact CG-CB 4.14Å; R169-A173 CarbonylContact O-C 3.54Å; R169-A173 WeakPolarHBondContact O-CA 3.48Å; R169-A173 WeakPolarHBondContact O-CB 3.33Å; R169-A173 PolarHBondContact O-N 3.17Å; A173-T248 WeakPolarHBondContact CA-OG1 3.18Å; A173-T248 WeakPolarHBondContact O-CG2 3.35Å; A173-T251 HydrophobicContact CB-CG2 3.96Å
174A76.8Confident79.6Confident4 Ų419.6 Ų19.63%0.03310%0.099CC..  trans-121.5140.8175.900000110.9V176 P246 P501A174-V176 PolarHBondContact O-N 3.45Å; A174-P246 HydrophobicContact CB-CB 4.24Å; A174-P501 HydrophobicContact CB-CB 3.56Å; A174-P501 HydrophobicContact CB-CG 3.55Å
175H78.5Confident79.8Confident113 Ų11318.9 Ų18.952%0.52310%0.097SC..  trans-63.8128.4172.9-178.4-83.2000110.6Q170Q170-H175 HydrophobicContact CB-CB 4.36Å
176V81.5Confident80Confident6 Ų617.3 Ų17.34%0.0369%0.089CC..  trans-127.2144.6176.3-65.30000109.6A174 V180 E181 L245 P246A174-V176 PolarHBondContact O-N 3.45Å; V176-V180 HydrophobicContact CB-CG2 4.47Å; V176-E181 HydrophobicContact CG2-CB 4.43Å; V176-E181 WeakPolarHBondContact CG2-OE2 3.43Å; V176-L245 HydrophobicContact CG1-CD2 4.41Å; V176-L245 HydrophobicContact CG2-CD1 4.5Å; V176-P246 HydrophobicContact CG1-CG 4.34Å
177P85.4Confident80.2Confident17 Ų1721.7 Ų21.711%0.1111%0.109CC..  trans-65143.4176.6-23.835.3000112.3S179 V180 Y724P177-S179 PolarHBondContact O-N 2.69Å; P177-V180 WeakPolarHBondContact O-CG2 3.39Å; P177-V180 PolarHBondContact O-N 2.98Å; P177-V180 VanDerWaalsContact O-N 3.17Å; P177-Y724 WeakPolarHBondContact CB-O 3.26Å; P177-Y724 WeakPolarHBondContact CD-OH 2.89Å; P177-Y724 HydrophobicContact CG-CD1 4.06Å; P177-Y724 HydrophobicContact CG-CE1 3.57Å; P177-Y724 HydrophobicContact CG-CE2 4.08Å; P177-Y724 VanDerWaalsContact CG-O 3.31Å; P177-Y724 WeakPolarHBondContact CG-O 3.49Å
178P86.9Confident80.7Confident16 Ų1624.3 Ų24.310%0.10413%0.125CC..THydrogen-bonded Turntrans-56.9-18.8176.8-26.432.8000115.8Q166 V180 V201 Y204Q166-P178 VanDerWaalsContact NE2-CA 3.32Å; P178-V180 VanDerWaalsContact C-N 3.29Å; P178-V180 PolarHBondContact O-N 3.04Å; P178-V201 HydrophobicContact CB-CG2 4.15Å; P178-Y204 HydrophobicContact CG-CD1 4.43Å; P178-Y204 HydrophobicContact CG-CD2 3.83Å; P178-Y204 HydrophobicContact CG-CG 3.76Å
179S88Confident81.3Confident2 Ų224.8 Ų24.81%0.01413%0.127CC..THydrogen-bonded Turntrans-68-23.3178.449.60000115.2P177 P191 R197 Y724 S726P177-S179 PolarHBondContact O-N 2.69Å; S179-P191 WeakPolarHBondContact O-CA 3.34Å; S179-P191 VanDerWaalsContact O-CB 3.27Å; S179-P191 WeakPolarHBondContact O-CB 3.47Å; S179-R197 VanDerWaalsContact CB-CD 3.41Å; S179-Y724 PolarHBondContact OG-O 2.84Å; S179-S726 VanDerWaalsContact CB-OG 3.31Å; S179-S726 WeakPolarHBondContact CB-OG 3.45Å
180V88.1Confident81.8Confident6 Ų629 Ų294%0.03615%0.147CC..THydrogen-bonded Turntrans-111.8-1.7-178.5-62.30000112.5V176 P177 P178 Y189 L245 M719 Y724V176-V180 HydrophobicContact CB-CG2 4.47Å; P177-V180 WeakPolarHBondContact O-CG2 3.39Å; P177-V180 PolarHBondContact O-N 2.98Å; P177-V180 VanDerWaalsContact O-N 3.17Å; P178-V180 VanDerWaalsContact C-N 3.29Å; P178-V180 PolarHBondContact O-N 3.04Å; V180-Y189 PolarHBondContact O-OH 3.26Å; V180-L245 HydrophobicContact CG2-CD2 4.18Å; V180-M719 HydrophobicContact CG1-SD 3.69Å; V180-Y724 HydrophobicContact CG1-CD2 3.77Å; V180-Y724 HydrophobicContact CG1-CE2 3.81Å; V180-Y724 HydrophobicContact CG2-CE2 4.07Å
181E85.6Confident82.4Confident10 Ų1027.4 Ų27.45%0.04714%0.142CC..SBendtrans-91.6143.7179.7-167.7157.9-166.300110.5Q166 V176 L245Q166-E181 VanDerWaalsContact CA-OE1 3.28Å; Q166-E181 WeakPolarHBondContact CA-OE1 3.3Å; Q166-E181 VanDerWaalsContact CB-CD 3.49Å; Q166-E181 HydrophobicContact CB-CG 4.47Å; Q166-E181 WeakPolarHBondContact CB-OE1 3.23Å; Q166-E181 WeakPolarHBondContact CB-OE2 3.36Å; Q166-E181 WeakPolarHBondContact CG-OE2 3.36Å; Q166-E181 PolarHBondContact NE2-OE2 3.48Å; V176-E181 HydrophobicContact CG2-CB 4.43Å; V176-E181 WeakPolarHBondContact CG2-OE2 3.43Å; E181-L245 HydrophobicContact CG-CD1 4.34Å
182L86.6Confident83Confident8 Ų834.2 Ų34.24%0.04217%0.166CC..  trans-92.7119.1177.7179.356.9000109.6M186 Y189 I243 R381 I384 L385L182-M186 HydrophobicContact CD1-SD 4.01Å; L182-Y189 HydrophobicContact CB-CD2 4.18Å; L182-Y189 HydrophobicContact CB-CE2 4.41Å; L182-Y189 HydrophobicContact CD1-CD2 3.81Å; L182-Y189 HydrophobicContact CD1-CG 4.06Å; L182-I243 HydrophobicContact CB-CG1 4.1Å; L182-I243 HydrophobicContact CD2-CG1 4Å; L182-R381 HydrophobicContact CD2-CG 3.68Å; L182-R381 HydrophobicContact CG-CG 3.64Å; L182-R381 PolarHBondContact O-NE 2.73Å; L182-I384 HydrophobicContact CD1-CB 4.24Å; L182-I384 HydrophobicContact CD1-CD1 3.66Å; L182-I384 HydrophobicContact CD1-CG2 3.87Å; L182-I384 HydrophobicContact CD2-CB 4.41Å; L182-I384 HydrophobicContact CD2-CG2 4.37Å; L182-L385 HydrophobicContact CD2-CD2 3.81Å; L182-L385 HydrophobicContact CD2-CG 4.16Å
183T81.5Confident83.8Confident4 Ų436.7 Ų36.73%0.02518%0.18CC..  trans-104.9162.2-176.876.60000112.9S185 M186 D203T183-S185 PolarHBondContact O-N 3.37Å; T183-S185 PolarHBondContact OG1-N 3.28Å; T183-M186 HydrophobicContact CG2-CE 3.93Å; T183-M186 WeakPolarHBondContact OG1-CG 3.39Å; T183-D203 VanDerWaalsContact CB-OD2 3.3Å; T183-D203 WeakPolarHBondContact CB-OD2 3.37Å; T183-D203 HydrophobicContact CG2-CB 4.12Å
184M77.2Confident84.8Confident29 Ų2939.9 Ų39.914%0.14319%0.193CC..THydrogen-bonded Turntrans-73.3-11.3177.1-61.5-175-64.800112.9F105 L165 V380F105-M184 HydrophobicContact CD1-CE 3.91Å; F105-M184 HydrophobicContact CE1-CE 3.89Å; F105-M184 HydrophobicContact CG-CE 4.31Å; F105-M184 HydrophobicContact CZ-CE 4.26Å; L165-M184 HydrophobicContact CD2-CE 3.99Å; M184-V380 WeakPolarHBondContact O-CG1 3.37Å
185S80.1Confident85.4Confident19 Ų1946.2 Ų46.213%0.13322%0.219CC..THydrogen-bonded Turntrans-97.6-0.8-177.3-60.90000113.3V100 T183 D203V100-S185 WeakPolarHBondContact CG1-O 3.36Å; T183-S185 PolarHBondContact O-N 3.37Å; T183-S185 PolarHBondContact OG1-N 3.28Å; S185-D203 WeakPolarHBondContact CB-OD1 3.08Å; S185-D203 PolarHBondContact OG-OD1 3.49Å
186M80.9Confident86Confident5 Ų541.3 Ų41.33%0.02520%0.198CC..  trans-86.3150.7178.1-73170.9-176.200111.9L182 T183 Y189 S196 I199 I384L182-M186 HydrophobicContact CD1-SD 4.01Å; T183-M186 HydrophobicContact CG2-CE 3.93Å; T183-M186 WeakPolarHBondContact OG1-CG 3.39Å; M186-Y189 HydrophobicContact SD-CD2 4.5Å; M186-S196 VanDerWaalsContact CE-O 3.29Å; M186-S196 WeakPolarHBondContact CE-O 3.24Å; M186-I199 HydrophobicContact CG-CG2 3.93Å; M186-I384 HydrophobicContact CB-CD1 3.82Å; M186-I384 VanDerWaalsContact O-CD1 3.25Å; M186-I384 WeakPolarHBondContact O-CD1 3.24Å
187E79.4Confident86.5Confident100 Ų10041.4 Ų41.447%0.46720%0.198SC..SBendtrans-96.3-30.4168.8-67.5-177.1168.600111.9R98R98-E187 IonicContact NH1-OE1 3.65Å; R98-E187 PolarHBondContact NH1-OE1 3.16Å
188T84.4Confident86.8Confident57 Ų5742.3 Ų42.335%0.3520%0.202SC..SBendtrans-144.3145.6178.5590000110Q190T188-Q190 PolarHBondContact O-N 3.05Å
189Y88.8Confident86.9Confident20 Ų2043.8 Ų43.88%0.07821%0.208CC..  trans-92.998.8176.4-176.9-118.8000110.4V180 L182 M186 P191 I243 F388 K715V180-Y189 PolarHBondContact O-OH 3.26Å; L182-Y189 HydrophobicContact CB-CD2 4.18Å; L182-Y189 HydrophobicContact CB-CE2 4.41Å; L182-Y189 HydrophobicContact CD1-CD2 3.81Å; L182-Y189 HydrophobicContact CD1-CG 4.06Å; M186-Y189 HydrophobicContact SD-CD2 4.5Å; Y189-P191 HydrophobicContact CE1-CG 4.13Å; Y189-P191 HydrophobicContact CE2-CB 4.27Å; Y189-P191 HydrophobicContact CE2-CG 4.36Å; Y189-I243 HydrophobicContact CD1-CD1 3.58Å; Y189-I243 HydrophobicContact CD1-CG1 4.08Å; Y189-I243 HydrophobicContact CE1-CD1 3.56Å; Y189-I243 HydrophobicContact CE1-CG1 3.86Å; Y189-I243 HydrophobicContact CE1-CG2 3.85Å; Y189-I243 HydrophobicContact CG-CD1 4.43Å; Y189-F388 AromaticContact CD1-CD2 3.84Å; Y189-F388 HydrophobicContact CD1-CD2 3.84Å; Y189-F388 AromaticContact CD1-CE2 3.89Å; Y189-F388 HydrophobicContact CD1-CE2 3.89Å; Y189-F388 HydrophobicContact CE1-CE2 4.2Å; Y189-K715 HydrophobicContact CE1-CG 4.12Å
190Q89.2Confident87Confident101 Ų10143.7 Ų43.747%0.47221%0.207SC..  trans-13182.6176.4-66.7-174.2-20.300109.4T188 R192 N193 S196T188-Q190 PolarHBondContact O-N 3.05Å; Q190-R192 PolarHBondContact O-N 3.01Å; Q190-N193 HydrophobicContact CB-CB 3.75Å; Q190-N193 WeakPolarHBondContact O-CB 3.22Å; Q190-N193 PolarHBondContact O-N 3.45Å; Q190-N193 PolarHBondContact OE1-ND2 3.11Å; Q190-S196 VanDerWaalsContact O-CB 3.31Å; Q190-S196 WeakPolarHBondContact O-CB 3.29Å
191P88.2Confident87.1Confident20 Ų2043.7 Ų43.713%0.1321%0.207CC..THydrogen-bonded Turntrans-62.9-19.4-171.423.8-34.4000114S179 Y189 R197 K715 M719S179-P191 WeakPolarHBondContact O-CA 3.34Å; S179-P191 VanDerWaalsContact O-CB 3.27Å; S179-P191 WeakPolarHBondContact O-CB 3.47Å; Y189-P191 HydrophobicContact CE1-CG 4.13Å; Y189-P191 HydrophobicContact CE2-CB 4.27Å; Y189-P191 HydrophobicContact CE2-CG 4.36Å; P191-R197 WeakPolarHBondContact O-CD 3.47Å; P191-R197 VanDerWaalsContact O-CG 3.22Å; P191-R197 WeakPolarHBondContact O-CG 3.16Å; P191-K715 HydrophobicContact CG-CB 4.01Å; P191-M719 HydrophobicContact CB-SD 4.09Å; P191-M719 WeakPolarHBondContact O-CE 3.26Å
192R88.5Confident87.2Confident163 Ų16347.2 Ų47.262%0.61523%0.226SC*.THydrogen-bonded Turntrans-80.1-23.1172.9-67-175.5179.2178.5-1.3113.4Q190 T718 M719Q190-R192 PolarHBondContact O-N 3.01Å; R192-T718 PolarHBondContact NH2-OG1 2.82Å; R192-M719 HydrophobicContact CG-CG 4.32Å
193N91.4Very high87.2Confident64 Ų6447.2 Ų47.234%0.34223%0.226SC..SBendtrans-73.1130.8-177.3-171.1-59.5000110.2Q190 K195 S196 R197Q190-N193 HydrophobicContact CB-CB 3.75Å; Q190-N193 WeakPolarHBondContact O-CB 3.22Å; Q190-N193 PolarHBondContact O-N 3.45Å; Q190-N193 PolarHBondContact OE1-ND2 3.11Å; N193-K195 PolarHBondContact O-N 2.8Å; N193-K195 VanDerWaalsContact OD1-CB 3.31Å; N193-K195 WeakPolarHBondContact OD1-CB 3.38Å; N193-K195 PolarHBondContact OD1-N 3.32Å; N193-S196 PolarHBondContact O-N 3.01Å; N193-R197 WeakPolarHBondContact O-CG 3.26Å; N193-R197 PolarHBondContact O-N 2.94Å; N193-R197 VanDerWaalsContact O-N 3.13Å
194F93Very high87.3Confident74 Ų7449.3 Ų49.333%0.32523%0.234SC..Hα-helixtrans-59.7-43.6179.5-178-91.5000112.6S196 R197 L198 V729 F732F194-S196 PolarHBondContact O-N 2.97Å; F194-R197 PolarHBondContact O-N 3.12Å; F194-L198 HydrophobicContact CE1-CB 4.44Å; F194-L198 HydrophobicContact CE1-CD2 4.31Å; F194-L198 WeakPolarHBondContact O-CB 3.38Å; F194-L198 PolarHBondContact O-N 3.35Å; F194-V729 HydrophobicContact CD2-CG2 4.01Å; F194-V729 HydrophobicContact CE2-CB 4.34Å; F194-V729 HydrophobicContact CE2-CG2 3.71Å; F194-V729 HydrophobicContact CZ-CG2 4.27Å; F194-F732 HydrophobicContact CE1-CD1 4.06Å; F194-F732 HydrophobicContact CE1-CE1 4.3Å; F194-F732 HydrophobicContact CE1-CG 4.34Å; F194-F732 HydrophobicContact CE2-CB 4.39Å; F194-F732 HydrophobicContact CZ-CB 3.77Å; F194-F732 AromaticContact CZ-CD1 3.72Å; F194-F732 HydrophobicContact CZ-CD1 3.72Å; F194-F732 HydrophobicContact CZ-CD2 4.4Å; F194-F732 HydrophobicContact CZ-CE1 4.4Å; F194-F732 AromaticContact CZ-CG 3.7Å; F194-F732 HydrophobicContact CZ-CG 3.7Å
195K91.1Very high87.7Confident136 Ų13652.2 Ų52.259%0.59125%0.246SC*.Hα-helixtrans-61.4-44.6179.4-177.5-177.4176.6-177.10111.5N193 R197 L198 I199N193-K195 PolarHBondContact O-N 2.8Å; N193-K195 VanDerWaalsContact OD1-CB 3.31Å; N193-K195 WeakPolarHBondContact OD1-CB 3.38Å; N193-K195 PolarHBondContact OD1-N 3.32Å; K195-R197 VanDerWaalsContact C-N 3.34Å; K195-R197 PolarHBondContact O-N 3.42Å; K195-L198 PolarHBondContact O-N 2.96Å; K195-I199 HydrophobicContact CG-CD1 4.12Å; K195-I199 WeakPolarHBondContact O-CG1 3.49Å; K195-I199 PolarHBondContact O-N 3.17Å
196S89.6Confident87.8Confident10 Ų1053.5 Ų53.57%0.0725%0.253CS..Hα-helixtrans-60.4-45.1176.4-62.90000111M186 Q190 N193 F194 I199 G200M186-S196 VanDerWaalsContact CE-O 3.29Å; M186-S196 WeakPolarHBondContact CE-O 3.24Å; Q190-S196 VanDerWaalsContact O-CB 3.31Å; Q190-S196 WeakPolarHBondContact O-CB 3.29Å; N193-S196 PolarHBondContact O-N 3.01Å; F194-S196 PolarHBondContact O-N 2.97Å; S196-I199 PolarHBondContact O-N 3.27Å; S196-G200 PolarHBondContact O-N 3.49Å
197R92.4Very high87.7Confident8 Ų854.2 Ų54.23%0.0326%0.256CS..Hα-helixtrans-66.7-38.9177.9-65.9-172.1-71.2128.95.4113.2S179 P191 N193 F194 K195 G200 V201 T723 D728 V729S179-R197 VanDerWaalsContact CB-CD 3.41Å; P191-R197 WeakPolarHBondContact O-CD 3.47Å; P191-R197 VanDerWaalsContact O-CG 3.22Å; P191-R197 WeakPolarHBondContact O-CG 3.16Å; N193-R197 WeakPolarHBondContact O-CG 3.26Å; N193-R197 PolarHBondContact O-N 2.94Å; N193-R197 VanDerWaalsContact O-N 3.13Å; F194-R197 PolarHBondContact O-N 3.12Å; K195-R197 VanDerWaalsContact C-N 3.34Å; K195-R197 PolarHBondContact O-N 3.42Å; R197-G200 PolarHBondContact O-N 3.19Å; R197-V201 WeakPolarHBondContact O-CG2 3.28Å; R197-V201 PolarHBondContact O-N 3.02Å; R197-T723 PolarHBondContact NH1-O 3.26Å; R197-T723 VanDerWaalsContact NH1-O 3.09Å; R197-D728 IonicContact CZ-OD1 2.86Å; R197-D728 IonicContact CZ-OD2 3.35Å; R197-D728 IonicContact NH1-OD1 3.66Å; R197-D728 PolarHBondContact NH1-OD1 2.68Å; R197-D728 IonicContact NH1-OD2 3.37Å; R197-D728 PolarHBondContact NH1-OD2 3.44Å; R197-D728 IonicContact NH2-OD1 3.45Å; R197-D728 IonicContact NH2-OD2 3.12Å; R197-D728 PolarHBondContact NH2-OD2 3.15Å; R197-V729 HydrophobicContact CB-CG2 3.93Å
198L92.5Very high87.7Confident37 Ų3751.6 Ų51.619%0.19424%0.244CC..Hα-helixtrans-59.2-46.8173.2177.263.5000111.3F194 K195 G200 V201 L202 V729 F732 M733F194-L198 HydrophobicContact CE1-CB 4.44Å; F194-L198 HydrophobicContact CE1-CD2 4.31Å; F194-L198 WeakPolarHBondContact O-CB 3.38Å; F194-L198 PolarHBondContact O-N 3.35Å; K195-L198 PolarHBondContact O-N 2.96Å; L198-G200 VanDerWaalsContact C-N 3.31Å; L198-G200 PolarHBondContact O-N 3.48Å; L198-V201 PolarHBondContact O-N 3.02Å; L198-L202 HydrophobicContact CD1-CD1 4.26Å; L198-L202 HydrophobicContact CD1-CG 4.31Å; L198-L202 HydrophobicContact CG-CD1 4.16Å; L198-L202 WeakPolarHBondContact O-CG 3.44Å; L198-L202 PolarHBondContact O-N 2.96Å; L198-V729 HydrophobicContact CB-CG1 4.15Å; L198-V729 HydrophobicContact CD1-CG1 3.72Å; L198-F732 HydrophobicContact CD2-CE1 4.32Å; L198-M733 HydrophobicContact CD1-CG 4.09Å; L198-M733 HydrophobicContact CD1-SD 4.16Å
199I88.9Confident87.3Confident46 Ų4653.6 Ų53.624%0.23625%0.252CS..Hα-helixtrans-60-43.4174.4-67.8166.3000110.6M186 K195 S196 V201 L202 D203M186-I199 HydrophobicContact CG-CG2 3.93Å; K195-I199 HydrophobicContact CG-CD1 4.12Å; K195-I199 WeakPolarHBondContact O-CG1 3.49Å; K195-I199 PolarHBondContact O-N 3.17Å; S196-I199 PolarHBondContact O-N 3.27Å; I199-V201 PolarHBondContact O-N 3.41Å; I199-L202 PolarHBondContact O-N 2.94Å; I199-D203 VanDerWaalsContact O-CB 3.3Å; I199-D203 WeakPolarHBondContact O-CB 3.49Å; I199-D203 PolarHBondContact O-N 3.32Å
200G89.2Confident86.6Confident0 Ų054 Ų540%025%0.254CS..Hα-helixtrans-59.4-44.4176.900000113.1S196 R197 L198 D203 Y204S196-G200 PolarHBondContact O-N 3.49Å; R197-G200 PolarHBondContact O-N 3.19Å; L198-G200 VanDerWaalsContact C-N 3.31Å; L198-G200 PolarHBondContact O-N 3.48Å; G200-D203 PolarHBondContact O-N 2.8Å; G200-Y204 WeakPolarHBondContact O-CB 3.16Å; G200-Y204 PolarHBondContact O-N 3.43Å
201V90.9Very high85.7Confident6 Ų650.4 Ų50.44%0.03624%0.237CC..Hα-helixtrans-66.7-43.3177171.30000111.7P178 R197 L198 I199 Y204 F205 V729 L730 M733P178-V201 HydrophobicContact CB-CG2 4.15Å; R197-V201 WeakPolarHBondContact O-CG2 3.28Å; R197-V201 PolarHBondContact O-N 3.02Å; L198-V201 PolarHBondContact O-N 3.02Å; I199-V201 PolarHBondContact O-N 3.41Å; V201-Y204 WeakPolarHBondContact O-CB 3.42Å; V201-Y204 PolarHBondContact O-N 3.31Å; V201-F205 HydrophobicContact CG1-CD2 3.91Å; V201-F205 HydrophobicContact CG1-CE2 3.55Å; V201-F205 WeakPolarHBondContact O-CD2 3.27Å; V201-F205 PolarHBondContact O-N 3.19Å; V201-F205 VanDerWaalsContact O-N 3.1Å; V201-V729 HydrophobicContact CB-CG1 4.09Å; V201-V729 HydrophobicContact CG1-CG1 4.37Å; V201-V729 HydrophobicContact CG2-CB 4.48Å; V201-V729 HydrophobicContact CG2-CG1 3.95Å; V201-L730 HydrophobicContact CG1-CD2 4.12Å; V201-M733 HydrophobicContact CG1-SD 3.81Å
202L88.5Confident84.8Confident85 Ų8552.9 Ų52.945%0.44525%0.248SC..Hα-helixtrans-63-43.8176.4-70.6172.9000111.6L198 I199 Y204 F205 V206 M733L198-L202 HydrophobicContact CD1-CD1 4.26Å; L198-L202 HydrophobicContact CD1-CG 4.31Å; L198-L202 HydrophobicContact CG-CD1 4.16Å; L198-L202 WeakPolarHBondContact O-CG 3.44Å; L198-L202 PolarHBondContact O-N 2.96Å; I199-L202 PolarHBondContact O-N 2.94Å; L202-Y204 VanDerWaalsContact C-N 3.33Å; L202-Y204 PolarHBondContact O-N 3.24Å; L202-F205 PolarHBondContact O-N 3.49Å; L202-V206 WeakPolarHBondContact O-CG2 3.38Å; L202-V206 PolarHBondContact O-N 3.02Å; L202-M733 HydrophobicContact CD2-CE 3.95Å
203D84.9Confident83.8Confident7 Ų749.9 Ų49.94%0.03724%0.244CC..Hα-helixtrans-64.6-38.6177.9-160.874000111.4T183 S185 I199 G200 F205 V206 Q207T183-D203 VanDerWaalsContact CB-OD2 3.3Å; T183-D203 WeakPolarHBondContact CB-OD2 3.37Å; T183-D203 HydrophobicContact CG2-CB 4.12Å; S185-D203 WeakPolarHBondContact CB-OD1 3.08Å; S185-D203 PolarHBondContact OG-OD1 3.49Å; I199-D203 VanDerWaalsContact O-CB 3.3Å; I199-D203 WeakPolarHBondContact O-CB 3.49Å; I199-D203 PolarHBondContact O-N 3.32Å; G200-D203 PolarHBondContact O-N 2.8Å; D203-F205 PolarHBondContact O-N 3.5Å; D203-V206 PolarHBondContact O-N 3.49Å; D203-Q207 WeakPolarHBondContact O-CB 3.41Å; D203-Q207 WeakPolarHBondContact O-CG 3.43Å; D203-Q207 PolarHBondContact O-N 2.99Å; D203-Q207 PolarHBondContact OD2-NE2 2.91Å
204Y85.4Confident82.6Confident49 Ų4947.1 Ų47.119%0.19223%0.229CC..Hα-helixtrans-54.9-50.8170.9176.8-93.5000111.1Q166 P178 G200 V201 L202 V206 Q207 Q208Q166-Y204 HydrophobicContact CG-CD2 3.7Å; Q166-Y204 HydrophobicContact CG-CE2 4.38Å; P178-Y204 HydrophobicContact CG-CD1 4.43Å; P178-Y204 HydrophobicContact CG-CD2 3.83Å; P178-Y204 HydrophobicContact CG-CG 3.76Å; G200-Y204 WeakPolarHBondContact O-CB 3.16Å; G200-Y204 PolarHBondContact O-N 3.43Å; V201-Y204 WeakPolarHBondContact O-CB 3.42Å; V201-Y204 PolarHBondContact O-N 3.31Å; L202-Y204 VanDerWaalsContact C-N 3.33Å; L202-Y204 PolarHBondContact O-N 3.24Å; Y204-V206 PolarHBondContact O-N 2.88Å; Y204-Q207 PolarHBondContact O-N 2.89Å; Y204-Q208 HydrophobicContact CD1-CG 4.15Å; Y204-Q208 HydrophobicContact CE1-CG 3.79Å; Y204-Q208 HydrophobicContact CE2-CG 4.26Å; Y204-Q208 VanDerWaalsContact O-CG 3.29Å; Y204-Q208 WeakPolarHBondContact O-CG 3.46Å; Y204-Q208 PolarHBondContact O-N 3.45Å; Y204-Q208 PolarHBondContact OH-NE2 3.31Å
205F84.7Confident81.2Confident90 Ų9043.9 Ų43.940%0.39522%0.215SC..Hα-helixtrans-62.3-42.2177.8-75.6-64000112.6V201 L202 D203 Q207 Q208 N209 L730 M733V201-F205 HydrophobicContact CG1-CD2 3.91Å; V201-F205 HydrophobicContact CG1-CE2 3.55Å; V201-F205 WeakPolarHBondContact O-CD2 3.27Å; V201-F205 PolarHBondContact O-N 3.19Å; V201-F205 VanDerWaalsContact O-N 3.1Å; L202-F205 PolarHBondContact O-N 3.49Å; D203-F205 PolarHBondContact O-N 3.5Å; F205-Q207 PolarHBondContact O-N 3.42Å; F205-Q208 PolarHBondContact O-N 3Å; F205-N209 WeakPolarHBondContact O-CB 3.47Å; F205-N209 PolarHBondContact O-N 3.06Å; F205-N209 PolarHBondContact O-ND2 3.17Å; F205-L730 HydrophobicContact CE2-CD2 4.4Å; F205-L730 HydrophobicContact CZ-CD2 4.48Å; F205-M733 HydrophobicContact CD2-CE 4.35Å; F205-M733 HydrophobicContact CE2-CE 4.11Å
206V82.1Confident79.9Confident46 Ų4642.2 Ų42.228%0.27922%0.217SC..Hα-helixtrans-60.9-45176.8171.10000110.9P102 L106 L202 D203 Y204 N209 F210P102-V206 HydrophobicContact CB-CG1 4.32Å; L106-V206 HydrophobicContact CD1-CG1 4.21Å; L202-V206 WeakPolarHBondContact O-CG2 3.38Å; L202-V206 PolarHBondContact O-N 3.02Å; D203-V206 PolarHBondContact O-N 3.49Å; Y204-V206 PolarHBondContact O-N 2.88Å; V206-N209 PolarHBondContact O-N 3.19Å; V206-F210 WeakPolarHBondContact O-CB 3.39Å; V206-F210 PolarHBondContact O-N 3.03Å
207Q79.3Confident78.4Confident19 Ų1945.4 Ų45.49%0.08923%0.233CC..Hα-helixtrans-64.1-42177.7-72.7-175.847.900112.1C167 D203 Y204 F205 F210 W211C167-Q207 HydrophobicContact CB-CB 4.02Å; D203-Q207 WeakPolarHBondContact O-CB 3.41Å; D203-Q207 WeakPolarHBondContact O-CG 3.43Å; D203-Q207 PolarHBondContact O-N 2.99Å; D203-Q207 PolarHBondContact OD2-NE2 2.91Å; Y204-Q207 PolarHBondContact O-N 2.89Å; F205-Q207 PolarHBondContact O-N 3.42Å; Q207-F210 PolarHBondContact O-N 3.49Å; Q207-W211 VanDerWaalsContact O-CB 3.28Å; Q207-W211 WeakPolarHBondContact O-CB 3.17Å; Q207-W211 PolarHBondContact O-N 2.89Å
208Q78Confident76.7Confident46 Ų4646 Ų4622%0.21524%0.237CC..Hα-helixtrans-63.8-42.1176.7-67.6-62-21.900111.9Q170 Y204 F205 W211 L212Q170-Q208 VanDerWaalsContact NE2-NE2 3.1Å; Y204-Q208 HydrophobicContact CD1-CG 4.15Å; Y204-Q208 HydrophobicContact CE1-CG 3.79Å; Y204-Q208 HydrophobicContact CE2-CG 4.26Å; Y204-Q208 VanDerWaalsContact O-CG 3.29Å; Y204-Q208 WeakPolarHBondContact O-CG 3.46Å; Y204-Q208 PolarHBondContact O-N 3.45Å; Y204-Q208 PolarHBondContact OH-NE2 3.31Å; F205-Q208 PolarHBondContact O-N 3Å; Q208-W211 PolarHBondContact O-N 3.29Å; Q208-L212 WeakPolarHBondContact O-CB 3.33Å; Q208-L212 PolarHBondContact O-N 2.96Å
209N77.4Confident74.8Confident99 Ų9948.2 Ų48.253%0.52926%0.255SS..Hα-helixtrans-67.8-42.3177-80.2-80.6000112.2F205 V206 W211 L212 L213F205-N209 WeakPolarHBondContact O-CB 3.47Å; F205-N209 PolarHBondContact O-N 3.06Å; F205-N209 PolarHBondContact O-ND2 3.17Å; V206-N209 PolarHBondContact O-N 3.19Å; N209-W211 VanDerWaalsContact C-N 3.27Å; N209-W211 PolarHBondContact O-N 2.92Å; N209-L212 WeakPolarHBondContact O-CB 3.38Å; N209-L212 PolarHBondContact O-N 3.5Å; N209-L213 PolarHBondContact O-N 3.21Å
210F73.6Confident72.7Confident27 Ų2753.2 Ų53.212%0.11827%0.271CS..Hα-helixtrans-58.1-44.3172.4171-109000111L106 A109 V206 Q207 L213 F214L106-F210 HydrophobicContact CB-CD2 4.13Å; L106-F210 HydrophobicContact CB-CE2 4.18Å; L106-F210 HydrophobicContact CD1-CB 3.92Å; L106-F210 HydrophobicContact CD1-CD2 3.88Å; L106-F210 HydrophobicContact CD1-CG 4.07Å; L106-F210 HydrophobicContact CD2-CB 3.83Å; L106-F210 HydrophobicContact CD2-CD1 3.56Å; L106-F210 HydrophobicContact CD2-CD2 3.31Å; L106-F210 HydrophobicContact CD2-CE1 3.87Å; L106-F210 HydrophobicContact CD2-CE2 3.63Å; L106-F210 HydrophobicContact CD2-CG 3.25Å; L106-F210 HydrophobicContact CD2-CZ 3.9Å; L106-F210 HydrophobicContact CG-CD2 3.93Å; L106-F210 HydrophobicContact CG-CE2 4.34Å; L106-F210 HydrophobicContact CG-CG 4.18Å; A109-F210 HydrophobicContact CB-CZ 4.17Å; V206-F210 WeakPolarHBondContact O-CB 3.39Å; V206-F210 PolarHBondContact O-N 3.03Å; Q207-F210 PolarHBondContact O-N 3.49Å; F210-L213 PolarHBondContact O-N 3.15Å; F210-F214 HydrophobicContact CZ-CD2 4.12Å; F210-F214 HydrophobicContact CZ-CG 4.5Å; F210-F214 VanDerWaalsContact O-CB 3.28Å; F210-F214 WeakPolarHBondContact O-CB 3.22Å; F210-F214 PolarHBondContact O-N 3.2Å
211W71Confident70.7Confident27 Ų2757.6 Ų57.610%0.10231%0.307CS..Hα-helixtrans-65.6-40-179.9-161.2-120.4000112.7I168 Q207 Q208 N209 F214 S215 I223 Y227I168-W211 HydrophobicContact CD1-CH2 3.79Å; I168-W211 HydrophobicContact CD1-CZ2 4.21Å; I168-W211 HydrophobicContact CD1-CZ3 4.19Å; I168-W211 HydrophobicContact CG1-CH2 4.08Å; I168-W211 HydrophobicContact CG1-CZ2 4.01Å; Q207-W211 VanDerWaalsContact O-CB 3.28Å; Q207-W211 WeakPolarHBondContact O-CB 3.17Å; Q207-W211 PolarHBondContact O-N 2.89Å; Q208-W211 PolarHBondContact O-N 3.29Å; N209-W211 VanDerWaalsContact C-N 3.27Å; N209-W211 PolarHBondContact O-N 2.92Å; W211-F214 HydrophobicContact CE3-CB 4.38Å; W211-F214 HydrophobicContact CE3-CD1 4.08Å; W211-F214 HydrophobicContact CH2-CD1 4.49Å; W211-F214 AromaticContact CZ3-CD1 3.79Å; W211-F214 HydrophobicContact CZ3-CD1 3.79Å; W211-F214 HydrophobicContact CZ3-CE1 4.27Å; W211-F214 PolarHBondContact O-N 3.28Å; W211-S215 WeakPolarHBondContact O-CB 3.42Å; W211-S215 PolarHBondContact O-N 3.09Å; W211-S215 PolarHBondContact O-OG 3.4Å; W211-I223 HydrophobicContact CH2-CG2 3.81Å; W211-I223 HydrophobicContact CZ2-CG2 3.05Å; W211-Y227 AromaticContact CH2-CE2 3.76Å; W211-Y227 HydrophobicContact CH2-CE2 3.76Å; W211-Y227 HydrophobicContact CZ2-CD2 4.16Å; W211-Y227 AromaticContact CZ2-CE2 3.5Å; W211-Y227 HydrophobicContact CZ2-CE2 3.5Å; W211-Y227 VanDerWaalsContact CZ2-CE2 3.5Å
212L68.7Low69.3Low72 Ų7259.1 Ų59.138%0.37732%0.318SS..Hα-helixtrans-57.6-49.2171.9-17965.6000111.2Q208 N209 F214 S215 T216 R220Q208-L212 WeakPolarHBondContact O-CB 3.33Å; Q208-L212 PolarHBondContact O-N 2.96Å; N209-L212 WeakPolarHBondContact O-CB 3.38Å; N209-L212 PolarHBondContact O-N 3.5Å; L212-F214 VanDerWaalsContact C-N 3.35Å; L212-F214 PolarHBondContact O-N 2.84Å; L212-S215 PolarHBondContact O-N 2.89Å; L212-S215 PolarHBondContact O-OG 2.99Å; L212-T216 PolarHBondContact O-N 3.14Å; L212-R220 VanDerWaalsContact CD1-NH1 3.34Å
213L68.1Low68.2Low99 Ų9955.1 Ų55.152%0.51830%0.297SS..Hα-helixtrans-66.5-35.7178-169.572.9000112.5W110 N209 F210 S215 T216W110-L213 HydrophobicContact CH2-CG 4.42Å; W110-L213 HydrophobicContact CZ3-CD2 4.18Å; W110-L213 HydrophobicContact CZ3-CG 4.16Å; N209-L213 PolarHBondContact O-N 3.21Å; F210-L213 PolarHBondContact O-N 3.15Å; L213-S215 VanDerWaalsContact C-N 3.31Å; L213-S215 PolarHBondContact O-N 3.4Å; L213-T216 PolarHBondContact O-N 2.65Å; L213-T216 PolarHBondContact O-OG1 2.68Å
214F65.7Low67.6Low7 Ų758.2 Ų58.23%0.03131%0.314CS..Hα-helixtrans-65.6-37.8176.8-165.5-109.7000111.6S113 L145 H146 F210 W211 L212 T216 L217 L218 I223S113-F214 VanDerWaalsContact CB-CE2 3.46Å; S113-F214 WeakPolarHBondContact OG-CE2 3.4Å; S113-F214 WeakPolarHBondContact OG-CZ 3.32Å; L145-F214 HydrophobicContact CD2-CE1 4.26Å; H146-F214 AromaticContact CE1-CZ 3.82Å; F210-F214 HydrophobicContact CZ-CD2 4.12Å; F210-F214 HydrophobicContact CZ-CG 4.5Å; F210-F214 VanDerWaalsContact O-CB 3.28Å; F210-F214 WeakPolarHBondContact O-CB 3.22Å; F210-F214 PolarHBondContact O-N 3.2Å; W211-F214 HydrophobicContact CE3-CB 4.38Å; W211-F214 HydrophobicContact CE3-CD1 4.08Å; W211-F214 HydrophobicContact CH2-CD1 4.49Å; W211-F214 AromaticContact CZ3-CD1 3.79Å; W211-F214 HydrophobicContact CZ3-CD1 3.79Å; W211-F214 HydrophobicContact CZ3-CE1 4.27Å; W211-F214 PolarHBondContact O-N 3.28Å; L212-F214 VanDerWaalsContact C-N 3.35Å; L212-F214 PolarHBondContact O-N 2.84Å; F214-T216 VanDerWaalsContact C-N 3.28Å; F214-T216 PolarHBondContact O-N 2.9Å; F214-L217 PolarHBondContact O-N 2.86Å; F214-L218 HydrophobicContact CD1-CD1 4.39Å; F214-L218 HydrophobicContact CE1-CD1 3.56Å; F214-L218 HydrophobicContact CE2-CD1 4.41Å; F214-L218 HydrophobicContact CZ-CD1 3.55Å; F214-L218 PolarHBondContact O-N 3Å; F214-I223 HydrophobicContact CD1-CD1 4.24Å
215S62.8Low67Low5 Ų559.2 Ų59.24%0.03532%0.322CS..Hα-helixtrans-72-14.7178.580.30000115.1W211 L212 L213 L218 R220W211-S215 WeakPolarHBondContact O-CB 3.42Å; W211-S215 PolarHBondContact O-N 3.09Å; W211-S215 PolarHBondContact O-OG 3.4Å; L212-S215 PolarHBondContact O-N 2.89Å; L212-S215 PolarHBondContact O-OG 2.99Å; L213-S215 VanDerWaalsContact C-N 3.31Å; L213-S215 PolarHBondContact O-N 3.4Å; S215-L218 CarbonylContact C-O 3.58Å; S215-L218 WeakPolarHBondContact CA-O 3.48Å; S215-L218 CarbonylContact O-C 3.5Å; S215-R220 WeakPolarHBondContact O-CA 3.35Å; S215-R220 PolarHBondContact O-N 3.3Å; S215-R220 WeakPolarHBondContact OG-CD 3.48Å; S215-R220 WeakPolarHBondContact OG-CG 3.39Å
216T64Low66.6Low101 Ų10155.1 Ų55.162%0.6230%0.304SS*.Hα-helixtrans-81.5-27172.260.30000111.9L212 L213 F214L212-T216 PolarHBondContact O-N 3.14Å; L213-T216 PolarHBondContact O-N 2.65Å; L213-T216 PolarHBondContact O-OG1 2.68Å; F214-T216 VanDerWaalsContact C-N 3.28Å; F214-T216 PolarHBondContact O-N 2.9Å
217L59Low66.4Low78 Ų7853.4 Ų53.441%0.40829%0.293SS..Hα-helixtrans-76.6-43.3172-76.4-177000113.1W110 T114 F214W110-L217 HydrophobicContact CD2-CD1 4.07Å; W110-L217 HydrophobicContact CE3-CD1 3.69Å; W110-L217 HydrophobicContact CH2-CD1 3.06Å; W110-L217 HydrophobicContact CH2-CD2 3.88Å; W110-L217 HydrophobicContact CH2-CG 3.39Å; W110-L217 HydrophobicContact CZ2-CD1 3.43Å; W110-L217 VanDerWaalsContact CZ2-CD1 3.43Å; W110-L217 HydrophobicContact CZ2-CD2 4.07Å; W110-L217 HydrophobicContact CZ2-CG 4Å; W110-L217 HydrophobicContact CZ3-CD1 3.18Å; W110-L217 HydrophobicContact CZ3-CG 3.8Å; T114-L217 HydrophobicContact CG2-CD1 4.32Å; F214-L217 PolarHBondContact O-N 2.86Å
218L56.8Low66.3Low21 Ų2153.9 Ų53.911%0.1130%0.297CS..THydrogen-bonded Turntrans-111.1107.8178.6-64.5173.3000106.7F117 L145 F214 S215 R220 I223F117-L218 HydrophobicContact CD2-CD2 3.54Å; F117-L218 HydrophobicContact CE2-CD2 3.98Å; F117-L218 HydrophobicContact CG-CD2 4.46Å; L145-L218 HydrophobicContact CD2-CB 4.25Å; L145-L218 HydrophobicContact CD2-CD1 3.83Å; F214-L218 HydrophobicContact CD1-CD1 4.39Å; F214-L218 HydrophobicContact CE1-CD1 3.56Å; F214-L218 HydrophobicContact CE2-CD1 4.41Å; F214-L218 HydrophobicContact CZ-CD1 3.55Å; F214-L218 PolarHBondContact O-N 3Å; S215-L218 CarbonylContact C-O 3.58Å; S215-L218 WeakPolarHBondContact CA-O 3.48Å; S215-L218 CarbonylContact O-C 3.5Å; L218-R220 PolarHBondContact O-N 2.94Å; L218-I223 HydrophobicContact CB-CD1 4.41Å
219S51.2Low66.3Low83 Ų8354.8 Ų54.858%0.5830%0.303SS*.THydrogen-bonded Turntrans-21.7106.4-176.955.10000114.3A221 S222S219-A221 PolarHBondContact O-N 3.46Å; S219-S222 WeakPolarHBondContact O-CB 3.47Å; S219-S222 PolarHBondContact O-N 3.31Å; S219-S222 PolarHBondContact O-OG 2.67Å; S219-S222 PolarHBondContact OG-OG 3.36Å
220R46Very low66.6Low151 Ų15150.3 Ų50.357%0.5728%0.28SS*.G310 helixtrans-46.9-36-175.4-169.5169.4-174.6-173.11.8115.1L212 S215 L218 S222 I223L212-R220 VanDerWaalsContact CD1-NH1 3.34Å; S215-R220 WeakPolarHBondContact O-CA 3.35Å; S215-R220 PolarHBondContact O-N 3.3Å; S215-R220 WeakPolarHBondContact OG-CD 3.48Å; S215-R220 WeakPolarHBondContact OG-CG 3.39Å; L218-R220 PolarHBondContact O-N 2.94Å; R220-S222 PolarHBondContact O-N 2.99Å; R220-I223 PolarHBondContact O-N 2.71Å
221A46.9Very low67.3Low91 Ų9149.3 Ų49.375%0.75228%0.276SS*.G310 helixtrans-62.3-16.4176.200000114.5S219 D225S219-A221 PolarHBondContact O-N 3.46Å; A221-D225 WeakPolarHBondContact O-CB 3.4Å
222S61.8Low68.1Low39 Ų3948.5 Ų48.527%0.27327%0.273SS..G310 helixtrans-91.7-12.1178.3730000113.9S219 R220 F226S219-S222 WeakPolarHBondContact O-CB 3.47Å; S219-S222 PolarHBondContact O-N 3.31Å; S219-S222 PolarHBondContact O-OG 2.67Å; S219-S222 PolarHBondContact OG-OG 3.36Å; R220-S222 PolarHBondContact O-N 2.99Å; S222-F226 VanDerWaalsContact O-CB 3.22Å; S222-F226 WeakPolarHBondContact O-CB 3.24Å; S222-F226 PolarHBondContact O-N 2.67Å
223I65.3Low69Low1 Ų145.1 Ų45.11%0.00526%0.256CS..Hα-helixtrans-91.6-57.8-169.4-51-157.4000112.1L145 W211 F214 L218 R220 D225 F226 Y227L145-I223 HydrophobicContact CD1-CG1 4.4Å; L145-I223 HydrophobicContact CD2-CB 4.13Å; L145-I223 HydrophobicContact CD2-CD1 3.37Å; L145-I223 HydrophobicContact CD2-CG1 3.37Å; L145-I223 HydrophobicContact CD2-CG2 4.1Å; W211-I223 HydrophobicContact CH2-CG2 3.81Å; W211-I223 HydrophobicContact CZ2-CG2 3.05Å; F214-I223 HydrophobicContact CD1-CD1 4.24Å; L218-I223 HydrophobicContact CB-CD1 4.41Å; R220-I223 PolarHBondContact O-N 2.71Å; I223-D225 PolarHBondContact O-N 2.96Å; I223-F226 WeakPolarHBondContact O-CB 3.42Å; I223-F226 PolarHBondContact O-N 3.33Å; I223-F226 VanDerWaalsContact O-N 3.14Å; I223-Y227 HydrophobicContact CG2-CD2 4.21Å; I223-Y227 HydrophobicContact CG2-CE2 3.97Å; I223-Y227 WeakPolarHBondContact O-CD2 3.48Å; I223-Y227 PolarHBondContact O-N 2.82Å
224D71.8Confident70Confident72 Ų7240.5 Ų40.539%0.38523%0.231SC..Hα-helixtrans-59.5-45.7177.3-67.4-17.8000108.4L171 F226 Y227 T228L171-D224 WeakPolarHBondContact CD1-OD1 3.41Å; D224-F226 VanDerWaalsContact C-N 3.28Å; D224-F226 PolarHBondContact O-N 2.64Å; D224-Y227 PolarHBondContact O-N 2.95Å; D224-T228 WeakPolarHBondContact O-CB 3.39Å; D224-T228 VanDerWaalsContact O-CG2 3.23Å; D224-T228 WeakPolarHBondContact O-CG2 3.21Å; D224-T228 PolarHBondContact O-N 3.18Å; D224-T228 PolarHBondContact O-OG1 2.68Å
225D72.8Confident71Confident70 Ų7040.6 Ų40.637%0.37424%0.235SC..Hα-helixtrans-52.1-43.6174.5-160.173.7000112.8W156 A221 I223 Y227 N229W156-D225 WeakPolarHBondContact CZ2-O 3.48Å; A221-D225 WeakPolarHBondContact O-CB 3.4Å; I223-D225 PolarHBondContact O-N 2.96Å; D225-Y227 VanDerWaalsContact C-N 3.35Å; D225-Y227 PolarHBondContact O-N 2.95Å; D225-N229 VanDerWaalsContact O-CB 3.22Å; D225-N229 WeakPolarHBondContact O-CB 3.47Å; D225-N229 PolarHBondContact O-N 3.28Å; D225-N229 PolarHBondContact OD1-ND2 2.84Å; D225-N229 PolarHBondContact OD2-ND2 3.41Å
226F76.2Confident71.8Confident4 Ų441 Ų412%0.01824%0.238CC..Hα-helixtrans-60.2-41.6177.2173-100.9000112.7P142 L145 A148 W156 D158 S222 I223 D224P142-F226 HydrophobicContact CB-CE2 4.4Å; P142-F226 HydrophobicContact CB-CZ 4.28Å; P142-F226 HydrophobicContact CG-CE2 3.56Å; P142-F226 HydrophobicContact CG-CZ 3.67Å; L145-F226 HydrophobicContact CD1-CB 3.69Å; L145-F226 HydrophobicContact CD1-CD1 4.1Å; L145-F226 HydrophobicContact CD1-CG 3.84Å; A148-F226 HydrophobicContact CB-CD2 3.27Å; A148-F226 HydrophobicContact CB-CE2 3.47Å; A148-F226 VanDerWaalsContact CB-CE2 3.47Å; A148-F226 HydrophobicContact CB-CG 4.11Å; A148-F226 HydrophobicContact CB-CZ 4.44Å; W156-F226 AromaticContact CD1-CD2 3.92Å; W156-F226 AromaticContact CD1-CE2 3.53Å; W156-F226 AromaticContact CE2-CD2 3.95Å; W156-F226 VanDerWaalsContact CE2-O 3.27Å; W156-F226 HydrophobicContact CG-CE2 4.27Å; W156-F226 HydrophobicContact CZ2-CD2 4.45Å; W156-F226 VanDerWaalsContact CZ2-O 3.27Å; W156-F226 WeakPolarHBondContact CZ2-O 3.45Å; W156-F226 AromaticContact NE1-CD2 3.46Å; W156-F226 AromaticContact NE1-CE2 3.55Å; W156-F226 PolarHBondContact NE1-O 3.2Å; D158-F226 HydrophobicContact CB-CE1 4.35Å; D158-F226 HydrophobicContact CB-CZ 4.29Å; S222-F226 VanDerWaalsContact O-CB 3.22Å; S222-F226 WeakPolarHBondContact O-CB 3.24Å; S222-F226 PolarHBondContact O-N 2.67Å; I223-F226 WeakPolarHBondContact O-CB 3.42Å; I223-F226 PolarHBondContact O-N 3.33Å; I223-F226 VanDerWaalsContact O-N 3.14Å; D224-F226 VanDerWaalsContact C-N 3.28Å; D224-F226 PolarHBondContact O-N 2.64Å
227Y78.1Confident72.8Confident9 Ų936.9 Ų36.94%0.03521%0.212CC..Hα-helixtrans-82.8-38.1-179.2-67.6-64.2000112.5D158 I168 L171 R172 W211 I223 D224 D225D158-Y227 WeakPolarHBondContact OD2-CD1 3.33Å; D158-Y227 WeakPolarHBondContact OD2-CE1 3.24Å; I168-Y227 HydrophobicContact CD1-CE2 4.43Å; I168-Y227 HydrophobicContact CG2-CD1 3.59Å; I168-Y227 HydrophobicContact CG2-CD2 3.98Å; I168-Y227 HydrophobicContact CG2-CE1 3.58Å; I168-Y227 HydrophobicContact CG2-CE2 3.99Å; I168-Y227 HydrophobicContact CG2-CG 3.79Å; L171-Y227 HydrophobicContact CB-CG 4.43Å; L171-Y227 HydrophobicContact CD1-CD2 4.11Å; L171-Y227 HydrophobicContact CD1-CG 4.48Å; R172-Y227 HydrophobicContact CG-CD1 3.64Å; R172-Y227 HydrophobicContact CG-CE1 4.34Å; R172-Y227 HydrophobicContact CG-CG 4.33Å; W211-Y227 AromaticContact CH2-CE2 3.76Å; W211-Y227 HydrophobicContact CH2-CE2 3.76Å; W211-Y227 HydrophobicContact CZ2-CD2 4.16Å; W211-Y227 AromaticContact CZ2-CE2 3.5Å; W211-Y227 HydrophobicContact CZ2-CE2 3.5Å; W211-Y227 VanDerWaalsContact CZ2-CE2 3.5Å; I223-Y227 HydrophobicContact CG2-CD2 4.21Å; I223-Y227 HydrophobicContact CG2-CE2 3.97Å; I223-Y227 WeakPolarHBondContact O-CD2 3.48Å; I223-Y227 PolarHBondContact O-N 2.82Å; D224-Y227 PolarHBondContact O-N 2.95Å; D225-Y227 VanDerWaalsContact C-N 3.35Å; D225-Y227 PolarHBondContact O-N 2.95Å
228T77.2Confident73.9Confident30 Ų3034 Ų3418%0.18420%0.198CC..Hα-helixtrans-78.5-28.3-174.261.40000113.2L171 D224 L462L171-T228 HydrophobicContact CB-CG2 4.42Å; L171-T228 HydrophobicContact CD2-CG2 4.16Å; D224-T228 WeakPolarHBondContact O-CB 3.39Å; D224-T228 VanDerWaalsContact O-CG2 3.23Å; D224-T228 WeakPolarHBondContact O-CG2 3.21Å; D224-T228 PolarHBondContact O-N 3.18Å; D224-T228 PolarHBondContact O-OG1 2.68Å; T228-L462 HydrophobicContact CG2-CD1 3.36Å
229N78.9Confident74.9Confident64 Ų6434.2 Ų34.234%0.34220%0.201SC..SBendtrans-100.11.4179.2-60.6-18.9000113.3W156 D225 V231W156-N229 HydrophobicContact CH2-CB 3.54Å; W156-N229 HydrophobicContact CZ2-CB 3.68Å; D225-N229 VanDerWaalsContact O-CB 3.22Å; D225-N229 WeakPolarHBondContact O-CB 3.47Å; D225-N229 PolarHBondContact O-N 3.28Å; D225-N229 PolarHBondContact OD1-ND2 2.84Å; D225-N229 PolarHBondContact OD2-ND2 3.41Å; N229-V231 PolarHBondContact O-N 3.05Å
230A83.8Confident76.5Confident5 Ų530.8 Ų30.84%0.04118%0.176CC..  trans-57.2134.917100000109.9D158 Y232D158-A230 HydrophobicContact CB-CB 4.09Å; A230-Y232 VanDerWaalsContact C-N 3.34Å; A230-Y232 PolarHBondContact O-N 3.23Å
231V87Confident78.5Confident7 Ų723.6 Ų23.64%0.04215%0.149CC..SBendtrans-59.4-50.2177.31710000110A155 W156 I157 N229 Y447 A454A155-V231 HydrophobicContact CB-CG2 4.13Å; W156-V231 WeakPolarHBondContact O-CB 3.39Å; W156-V231 WeakPolarHBondContact O-CG2 3.44Å; W156-V231 PolarHBondContact O-N 3.13Å; I157-V231 HydrophobicContact CG1-CB 4.04Å; I157-V231 HydrophobicContact CG1-CG1 4.35Å; N229-V231 PolarHBondContact O-N 3.05Å; V231-Y447 HydrophobicContact CB-CD2 4.32Å; V231-Y447 HydrophobicContact CB-CE2 4.3Å; V231-Y447 HydrophobicContact CG1-CD1 4.06Å; V231-Y447 HydrophobicContact CG1-CD2 3.26Å; V231-Y447 HydrophobicContact CG1-CE1 4.43Å; V231-Y447 HydrophobicContact CG1-CE2 3.68Å; V231-Y447 HydrophobicContact CG1-CG 3.48Å; V231-Y447 VanDerWaalsContact CG1-CG 3.48Å; V231-Y447 HydrophobicContact CG2-CD1 4.43Å; V231-Y447 HydrophobicContact CG2-CD2 4.07Å; V231-Y447 HydrophobicContact CG2-CE1 4Å; V231-Y447 HydrophobicContact CG2-CE2 3.57Å; V231-Y447 HydrophobicContact CG2-CG 4.47Å; V231-A454 HydrophobicContact CB-CB 4.43Å; V231-A454 HydrophobicContact CG1-CB 4.12Å; V231-A454 HydrophobicContact CG2-CB 4.21Å
232Y89Confident80.5Confident9 Ų920.6 Ų20.64%0.03512%0.12CC..  trans-138.6159.1174.7-58-53.1000110I157 D158 A230 N250 F252 W443 I457I157-Y232 WeakPolarHBondContact CA-O 3.47Å; I157-Y232 HydrophobicContact CD1-CD2 3.77Å; I157-Y232 HydrophobicContact CG1-CD2 4.11Å; D158-Y232 PolarHBondContact N-O 3.46Å; A230-Y232 VanDerWaalsContact C-N 3.34Å; A230-Y232 PolarHBondContact O-N 3.23Å; Y232-N250 CarbonylContact C-O 3.53Å; Y232-N250 WeakPolarHBondContact CA-O 3.23Å; Y232-N250 WeakPolarHBondContact CB-O 3.43Å; Y232-N250 HydrophobicContact CD1-CB 3.91Å; Y232-N250 HydrophobicContact CE1-CB 4.5Å; Y232-F252 HydrophobicContact CD1-CE1 4.25Å; Y232-F252 HydrophobicContact CD2-CE1 4.34Å; Y232-F252 AromaticContact CG-CE1 3.92Å; Y232-F252 HydrophobicContact CG-CE1 3.92Å; Y232-W443 HydrophobicContact CE2-CB 4.26Å; Y232-W443 WeakPolarHBondContact CE2-O 3.36Å; Y232-I457 HydrophobicContact CE1-CD1 4.12Å
233S87.7Confident81.6Confident2 Ų219 Ų191%0.01411%0.109CC..EExtended strand (participates in β ladder)trans-118.9121.8169.8-74.10000109.9D158 N250 T251 F252D158-S233 CarbonylContact O-C 3.58Å; D158-S233 VanDerWaalsContact O-CA 3.31Å; D158-S233 WeakPolarHBondContact O-CA 3.34Å; S233-N250 PolarHBondContact N-O 2.79Å; S233-T251 VanDerWaalsContact O-CA 3.26Å; S233-T251 WeakPolarHBondContact O-CA 3.41Å; S233-F252 PolarHBondContact O-N 3.07Å
234I88.8Confident82.4Confident1 Ų119.3 Ų19.31%0.00511%0.11CC..EExtended strand (participates in β ladder)trans-106.6125-178.6-58.9175000110.2L45 I157 D158 Y159 S160 F252 I254L45-I234 HydrophobicContact CD2-CD1 4.28Å; I157-I234 HydrophobicContact CG2-CD1 3.6Å; I157-I234 HydrophobicContact CG2-CG1 3.86Å; D158-I234 PolarHBondContact O-N 3.22Å; Y159-I234 HydrophobicContact CD1-CB 3.82Å; Y159-I234 HydrophobicContact CD1-CG2 3.59Å; Y159-I234 HydrophobicContact CE1-CB 4.4Å; Y159-I234 HydrophobicContact CE1-CG2 3.65Å; Y159-I234 HydrophobicContact CG-CB 4.06Å; Y159-I234 HydrophobicContact CG-CG2 4.13Å; S160-I234 WeakPolarHBondContact CB-O 3.31Å; S160-I234 PolarHBondContact N-O 3.1Å; I234-F252 CarbonylContact C-O 3.56Å; I234-F252 VanDerWaalsContact CA-O 3.22Å; I234-F252 WeakPolarHBondContact CA-O 3.39Å; I234-F252 HydrophobicContact CD1-CE2 4.05Å; I234-F252 HydrophobicContact CD1-CZ 4.1Å; I234-F252 HydrophobicContact CG1-CD2 4.39Å; I234-F252 HydrophobicContact CG1-CE2 3.76Å; I234-F252 HydrophobicContact CG1-CZ 3.85Å; I234-I254 HydrophobicContact CD1-CD1 3.94Å; I234-I254 HydrophobicContact CG2-CB 4Å; I234-I254 HydrophobicContact CG2-CD1 3.75Å; I234-I254 HydrophobicContact CG2-CG1 3.72Å
235G85.9Confident82.9Confident10 Ų1016.6 Ų16.610%0.10310%0.096CC..EExtended strand (participates in β ladder)trans-98.2158.6169.600000113F252 S253 I254G235-F252 PolarHBondContact N-O 3.36Å; G235-S253 CarbonylContact O-C 3.56Å; G235-S253 VanDerWaalsContact O-CA 3.22Å; G235-S253 WeakPolarHBondContact O-CA 3.43Å; G235-I254 PolarHBondContact O-N 3.48Å
236S80.9Confident83.2Confident14 Ų1414.5 Ų14.510%0.0989%0.086CC..SBendtrans-103.311.8-175.565.30000115.6S160 T161 I254 I357S160-S236 WeakPolarHBondContact O-CB 3.08Å; S160-S236 PolarHBondContact O-N 3.08Å; T161-S236 PolarHBondContact O-OG 2.88Å; S236-I254 WeakPolarHBondContact CA-O 3.4Å; S236-I357 VanDerWaalsContact OG-CD1 3.25Å; S236-I357 WeakPolarHBondContact OG-CD1 3.33Å
237M84.6Confident83.3Confident14 Ų1416.4 Ų16.47%0.06910%0.095CC..SBendtrans-136.5132.6179.5-173179.6-68.100110.6L241 D242 S253 I357 F360 N382 L385M237-L241 HydrophobicContact CG-CB 4.27Å; M237-L241 HydrophobicContact CG-CD2 4.23Å; M237-L241 HydrophobicContact CG-CG 4.34Å; M237-L241 HydrophobicContact SD-CG 4.33Å; M237-D242 HydrophobicContact CG-CB 4.25Å; M237-D242 HydrophobicContact SD-CB 3.79Å; M237-S253 WeakPolarHBondContact O-CB 2.98Å; M237-S253 PolarHBondContact O-OG 3.39Å; M237-I357 HydrophobicContact CB-CD1 4.35Å; M237-I357 HydrophobicContact CE-CD1 3.88Å; M237-I357 HydrophobicContact CE-CG1 3.69Å; M237-F360 HydrophobicContact CE-CD1 4.3Å; M237-F360 HydrophobicContact CE-CE1 4.41Å; M237-N382 WeakPolarHBondContact CE-OD1 3.39Å; M237-L385 HydrophobicContact CE-CD1 4.16Å; M237-L385 HydrophobicContact SD-CD1 3.64Å
238S81.8Confident83.2Confident17 Ų1716.2 Ų16.212%0.1199%0.094CC..  trans-58.6137.1172.7173.20000111.5M240 L241 D242 L429S238-M240 PolarHBondContact O-N 2.8Å; S238-M240 PolarHBondContact OG-N 2.84Å; S238-L241 PolarHBondContact O-N 3.26Å; S238-D242 PolarHBondContact O-N 3.25Å; S238-L429 WeakPolarHBondContact OG-CD2 3.32Å
239S78.3Confident83.1Confident26 Ų2618.4 Ų18.418%0.18210%0.103CC..THydrogen-bonded Turntrans-61.9-23.9174.743.20000113.4D242 I244 M504S239-D242 CarbonylContact O-C 3.6Å; S239-D242 VanDerWaalsContact O-O 3.09Å; S239-I244 WeakPolarHBondContact O-CD1 3.3Å; S239-M504 PolarHBondContact OG-SD 3.44Å
240M84Confident83.2Confident10 Ų1015.9 Ų15.95%0.0499%0.09CC..THydrogen-bonded Turntrans-69.2-34.6172.5-70.8-175.6-162.500112.7S238 H389 L429 M504 W698 F701S238-M240 PolarHBondContact O-N 2.8Å; S238-M240 PolarHBondContact OG-N 2.84Å; M240-H389 PolarHBondContact O-CE1 2.79Å; M240-L429 HydrophobicContact CB-CD2 3.66Å; M240-L429 HydrophobicContact SD-CD2 4.35Å; M240-M504 HydrophobicContact CB-CE 4.36Å; M240-M504 HydrophobicContact CE-CE 3.72Å; M240-M504 HydrophobicContact CE-SD 3.99Å; M240-M504 HydrophobicContact CG-CE 3.18Å; M240-M504 HydrophobicContact CG-SD 3.51Å; M240-M504 VanDerWaalsContact CG-SD 3.51Å; M240-M504 HydrophobicContact SD-CE 4.23Å; M240-W698 HydrophobicContact CE-CH2 3.78Å; M240-W698 HydrophobicContact CE-CZ3 3.77Å; M240-F701 HydrophobicContact CE-CE1 4.19Å; M240-F701 HydrophobicContact CE-CE2 4.21Å; M240-F701 HydrophobicContact CE-CZ 3.66Å; M240-F701 HydrophobicContact SD-CZ 4Å
241L88.3Confident83.2Confident1 Ų116 Ų161%0.0059%0.09CC..THydrogen-bonded Turntrans-81.2-29.4177.2-176.357.6000111M237 S238 F360 V364 H389 L425 L429M237-L241 HydrophobicContact CG-CB 4.27Å; M237-L241 HydrophobicContact CG-CD2 4.23Å; M237-L241 HydrophobicContact CG-CG 4.34Å; M237-L241 HydrophobicContact SD-CG 4.33Å; S238-L241 PolarHBondContact O-N 3.26Å; L241-F360 HydrophobicContact CD1-CE1 3.57Å; L241-F360 HydrophobicContact CD1-CZ 3.67Å; L241-F360 HydrophobicContact CD2-CD1 3.99Å; L241-F360 HydrophobicContact CD2-CE1 3.65Å; L241-F360 HydrophobicContact CG-CD1 4.41Å; L241-F360 HydrophobicContact CG-CE1 3.58Å; L241-F360 HydrophobicContact CG-CZ 4.2Å; L241-V364 HydrophobicContact CD1-CG2 4Å; L241-H389 PolarHBondContact O-NE2 2.73Å; L241-L425 HydrophobicContact CD1-CD2 3.96Å; L241-L429 HydrophobicContact CB-CD1 4.15Å; L241-L429 HydrophobicContact CB-CD2 4.33Å; L241-L429 HydrophobicContact CD1-CD1 4.28Å
242D87.9Confident83.1Confident27 Ų2716.5 Ų16.514%0.1449%0.092CC..SBendtrans-88-177.3176.6-153.10000113.5M237 S238 S239 R381M237-D242 HydrophobicContact CG-CB 4.25Å; M237-D242 HydrophobicContact SD-CB 3.79Å; S238-D242 PolarHBondContact O-N 3.25Å; S239-D242 CarbonylContact O-C 3.6Å; S239-D242 VanDerWaalsContact O-O 3.09Å; D242-R381 IonicContact OD1-CZ 3.47Å; D242-R381 IonicContact OD1-NH1 3Å; D242-R381 PolarHBondContact OD1-NH1 2.9Å; D242-R381 IonicContact OD1-NH2 2.87Å; D242-R381 PolarHBondContact OD1-NH2 2.93Å; D242-R381 IonicContact OD2-CZ 2.5Å; D242-R381 IonicContact OD2-NH1 2.94Å; D242-R381 IonicContact OD2-NH2 3.56Å; D242-R381 PolarHBondContact OD2-NH2 3.08Å
243I85.8Confident82.9Confident7 Ų716.9 Ų16.94%0.03610%0.096CC..  trans-76.5124.4164.9-55.4-52.8000109.1L182 Y189 L245 L385 F388L182-I243 HydrophobicContact CB-CG1 4.1Å; L182-I243 HydrophobicContact CD2-CG1 4Å; Y189-I243 HydrophobicContact CD1-CD1 3.58Å; Y189-I243 HydrophobicContact CD1-CG1 4.08Å; Y189-I243 HydrophobicContact CE1-CD1 3.56Å; Y189-I243 HydrophobicContact CE1-CG1 3.86Å; Y189-I243 HydrophobicContact CE1-CG2 3.85Å; Y189-I243 HydrophobicContact CG-CD1 4.43Å; I243-L245 HydrophobicContact CG2-CG 4.49Å; I243-L245 PolarHBondContact O-N 3.01Å; I243-L385 HydrophobicContact CD1-CD2 3.91Å; I243-L385 HydrophobicContact CG1-CD2 4.06Å; I243-F388 HydrophobicContact CD1-CD1 3.69Å; I243-F388 HydrophobicContact CD1-CD2 4.16Å; I243-F388 HydrophobicContact CD1-CE1 3.51Å; I243-F388 HydrophobicContact CD1-CE2 4Å; I243-F388 HydrophobicContact CD1-CG 4.01Å; I243-F388 HydrophobicContact CD1-CZ 3.67Å
244I82.3Confident82.9Confident7 Ų717 Ų174%0.03610%0.096CC..  trans-62.3121.1176.3-53.7-72.4000109.9S239 T503 M504 H711 L714S239-I244 WeakPolarHBondContact O-CD1 3.3Å; I244-T503 HydrophobicContact CG2-CG2 4.47Å; I244-M504 HydrophobicContact CD1-CB 4.28Å; I244-M504 HydrophobicContact CD1-CE 4.09Å; I244-H711 WeakPolarHBondContact CG1-O 3.48Å; I244-L714 HydrophobicContact CG2-CD2 4.08Å; I244-L714 HydrophobicContact CG2-CG 4.48Å; I244-L714 WeakPolarHBondContact O-CD2 3.46Å
245L82.3Confident82.4Confident15 Ų1517.8 Ų17.88%0.07910%0.101CC..  trans-136.5148.4176.7-66.8174.4000109V176 V180 E181 I243 Q247V176-L245 HydrophobicContact CG1-CD2 4.41Å; V176-L245 HydrophobicContact CG2-CD1 4.5Å; V180-L245 HydrophobicContact CG2-CD2 4.18Å; E181-L245 HydrophobicContact CG-CD1 4.34Å; I243-L245 HydrophobicContact CG2-CG 4.49Å; I243-L245 PolarHBondContact O-N 3.01Å; L245-Q247 PolarHBondContact O-N 2.75Å
246P79.1Confident82.1Confident25 Ų2520 Ų2016%0.16211%0.106CC..  trans-60135.8176.3-21.733.2000112.5R169 A174 V176 P501 Q502 T503 L714R169-P246 PolarHBondContact NH2-O 3.31Å; A174-P246 HydrophobicContact CB-CB 4.24Å; V176-P246 HydrophobicContact CG1-CG 4.34Å; P246-P501 HydrophobicContact CB-CB 3.74Å; P246-Q502 CarbonylContact C-O 3.58Å; P246-Q502 WeakPolarHBondContact CA-O 3.34Å; P246-T503 HydrophobicContact CB-CG2 4.05Å; P246-T503 HydrophobicContact CG-CG2 3.87Å; P246-L714 HydrophobicContact CG-CD2 4.21Å
247Q78.1Confident82.1Confident45 Ų4521.5 Ų21.521%0.2112%0.119CC..BIsolated β-bridgetrans-129.6149.7176.8-71-179.6-25.400109.6L245 P501 Q502L245-Q247 PolarHBondContact O-N 2.75Å; Q247-P501 CarbonylContact O-C 3.59Å; Q247-P501 WeakPolarHBondContact O-CA 3.47Å; Q247-Q502 PolarHBondContact N-O 2.99Å; Q247-Q502 PolarHBondContact O-N 2.58Å
248T76.6Confident82.2Confident4 Ų423.2 Ų23.23%0.02513%0.132CC..  trans-81159.4172.845.30000110.3A173 N250 T251 I499A173-T248 WeakPolarHBondContact CA-OG1 3.18Å; A173-T248 WeakPolarHBondContact O-CG2 3.35Å; T248-N250 WeakPolarHBondContact CB-OD1 3.42Å; T248-N250 PolarHBondContact O-N 3.38Å; T248-N250 PolarHBondContact OG1-OD1 3.48Å; T248-T251 WeakPolarHBondContact O-CA 3.33Å; T248-T251 WeakPolarHBondContact O-CB 3.29Å; T248-T251 PolarHBondContact O-N 2.85Å; T248-T251 VanDerWaalsContact O-O 3.04Å; T248-T251 PolarHBondContact OG1-OG1 2.04Å; T248-I499 HydrophobicContact CG2-CG2 3.75Å
249M74.6Confident82.4Confident76 Ų7623.7 Ų23.737%0.37413%0.134SC..THydrogen-bonded Turntrans-62.9-25.5-175.5-17359.56900113.8T251 T494M249-T251 PolarHBondContact O-N 3.07Å; M249-T494 HydrophobicContact CB-CG2 4.08Å; M249-T494 HydrophobicContact CE-CG2 3.67Å; M249-T494 HydrophobicContact CG-CG2 3.95Å
250N80.8Confident82.7Confident12 Ų1231.6 Ų31.66%0.06417%0.166CC..THydrogen-bonded Turntrans-79.9-1.4173.866-29000113.5Y232 S233 T248 I457Y232-N250 CarbonylContact C-O 3.53Å; Y232-N250 WeakPolarHBondContact CA-O 3.23Å; Y232-N250 WeakPolarHBondContact CB-O 3.43Å; Y232-N250 HydrophobicContact CD1-CB 3.91Å; Y232-N250 HydrophobicContact CE1-CB 4.5Å; S233-N250 PolarHBondContact N-O 2.79Å; T248-N250 WeakPolarHBondContact CB-OD1 3.42Å; T248-N250 PolarHBondContact O-N 3.38Å; T248-N250 PolarHBondContact OG1-OD1 3.48Å; N250-I457 HydrophobicContact CB-CG2 3.3Å; N250-I457 VanDerWaalsContact CG-CG2 3.48Å; N250-I457 WeakPolarHBondContact ND2-CG2 3.28Å
251T84.4Confident82.4Confident7 Ų735.5 Ų35.54%0.04320%0.2CC..EExtended strand (participates in β ladder)trans-113.1119.6175.8-39.90000109.3M164 R172 A173 S233 T248 M249M164-T251 HydrophobicContact CE-CG2 3.68Å; R172-T251 PolarHBondContact O-OG1 3.37Å; A173-T251 HydrophobicContact CB-CG2 3.96Å; S233-T251 VanDerWaalsContact O-CA 3.26Å; S233-T251 WeakPolarHBondContact O-CA 3.41Å; T248-T251 WeakPolarHBondContact O-CA 3.33Å; T248-T251 WeakPolarHBondContact O-CB 3.29Å; T248-T251 PolarHBondContact O-N 2.85Å; T248-T251 VanDerWaalsContact O-O 3.04Å; T248-T251 PolarHBondContact OG1-OG1 2.04Å; M249-T251 PolarHBondContact O-N 3.07Å
252F83.6Confident82.1Confident18 Ų1837.9 Ų37.98%0.07922%0.219CC..EExtended strand (participates in β ladder)trans-142159.8175.855.4-90.3000110.5Y232 S233 I234 G235 I254 W443Y232-F252 HydrophobicContact CD1-CE1 4.25Å; Y232-F252 HydrophobicContact CD2-CE1 4.34Å; Y232-F252 AromaticContact CG-CE1 3.92Å; Y232-F252 HydrophobicContact CG-CE1 3.92Å; S233-F252 PolarHBondContact O-N 3.07Å; I234-F252 CarbonylContact C-O 3.56Å; I234-F252 VanDerWaalsContact CA-O 3.22Å; I234-F252 WeakPolarHBondContact CA-O 3.39Å; I234-F252 HydrophobicContact CD1-CE2 4.05Å; I234-F252 HydrophobicContact CD1-CZ 4.1Å; I234-F252 HydrophobicContact CG1-CD2 4.39Å; I234-F252 HydrophobicContact CG1-CE2 3.76Å; I234-F252 HydrophobicContact CG1-CZ 3.85Å; G235-F252 PolarHBondContact N-O 3.36Å; F252-I254 HydrophobicContact CD2-CG1 4.34Å; F252-I254 HydrophobicContact CE2-CD1 4.32Å; F252-I254 HydrophobicContact CE2-CG1 4.17Å; F252-W443 HydrophobicContact CE1-CB 4.14Å; F252-W443 HydrophobicContact CE1-CG 4.28Å; F252-W443 HydrophobicContact CZ-CB 3.88Å; F252-W443 HydrophobicContact CZ-CG 4.29Å
253S85.5Confident82.2Confident16 Ų1644.2 Ų44.211%0.11225%0.253CS..EExtended strand (participates in β ladder)trans-96.5141.7173.7-64.20000110.3G235 M237 E436G235-S253 CarbonylContact O-C 3.56Å; G235-S253 VanDerWaalsContact O-CA 3.22Å; G235-S253 WeakPolarHBondContact O-CA 3.43Å; M237-S253 WeakPolarHBondContact O-CB 2.98Å; M237-S253 PolarHBondContact O-OG 3.39Å; S253-E436 VanDerWaalsContact O-OE2 3.07Å
254I86.6Confident82.7Confident6 Ų644.9 Ų44.93%0.03126%0.257CS..  trans-106.5108.8158.3-63174.4000105.5L45 I234 G235 S236 F252 E436L45-I254 HydrophobicContact CD1-CD1 3.98Å; L45-I254 HydrophobicContact CD2-CD1 3.54Å; L45-I254 HydrophobicContact CG-CD1 4.29Å; I234-I254 HydrophobicContact CD1-CD1 3.94Å; I234-I254 HydrophobicContact CG2-CB 4Å; I234-I254 HydrophobicContact CG2-CD1 3.75Å; I234-I254 HydrophobicContact CG2-CG1 3.72Å; G235-I254 PolarHBondContact O-N 3.48Å; S236-I254 WeakPolarHBondContact CA-O 3.4Å; F252-I254 HydrophobicContact CD2-CG1 4.34Å; F252-I254 HydrophobicContact CE2-CD1 4.32Å; F252-I254 HydrophobicContact CE2-CG1 4.17Å; I254-E436 HydrophobicContact CG2-CB 4.39Å
255D79.4Confident83.3Confident17 Ų1748.4 Ų48.49%0.09128%0.278CS..  trans-68.9149.4-179.5-162.516.4000110.9A257 R361 E436D255-A257 PolarHBondContact O-N 3.32Å; D255-A257 VanDerWaalsContact O-N 3.1Å; D255-R361 IonicContact OD1-NE 3.44Å; D255-R361 PolarHBondContact OD1-NE 3.21Å; D255-R361 IonicContact OD2-CZ 2.9Å; D255-R361 IonicContact OD2-NE 2.82Å; D255-R361 PolarHBondContact OD2-NE 2.99Å; D255-R361 IonicContact OD2-NH2 3.96Å; D255-R361 PolarHBondContact OD2-NH2 2.79Å; D255-E436 HydrophobicContact CB-CG 4.41Å
256Y80.2Confident84Confident57 Ų5756.5 Ų56.522%0.22431%0.309CS..  trans-66.3114.3171.2175.1-103.2000108.8C258 P259 K358 R361 E362Y256-C258 PolarHBondContact O-N 2.75Å; Y256-P259 HydrophobicContact CE1-CG 4.19Å; Y256-K358 HydrophobicContact CD1-CB 4.48Å; Y256-K358 HydrophobicContact CD1-CG 4.5Å; Y256-K358 HydrophobicContact CD2-CD 3.97Å; Y256-K358 HydrophobicContact CD2-CG 4.14Å; Y256-K358 HydrophobicContact CE1-CB 4.32Å; Y256-K358 HydrophobicContact CE2-CD 3.72Å; Y256-K358 HydrophobicContact CE2-CG 4.24Å; Y256-K358 HydrophobicContact CG-CG 4.26Å; Y256-R361 HydrophobicContact CD1-CB 4.22Å; Y256-R361 HydrophobicContact CD1-CG 4.07Å; Y256-E362 HydrophobicContact CE1-CG 3.75Å; Y256-E362 WeakPolarHBondContact CE1-OE1 3.21Å; Y256-E362 PolarHBondContact OH-OE1 3.06Å
257A79.8Confident84.8Confident44 Ų4460.9 Ų60.936%0.36433%0.327SS..PPolyproline II helixtrans-58.5138179.500000110.6D255D255-A257 PolarHBondContact O-N 3.32Å; D255-A257 VanDerWaalsContact O-N 3.1Å
258C87Confident85.8Confident50 Ų5059.6 Ų59.634%0.33832%0.321SS..PPolyproline II helixtrans-57.9130.6174.7-620000109.5Y256 K260 C365Y256-C258 PolarHBondContact O-N 2.75Å; C258-K260 PolarHBondContact O-N 3.31Å; C258-C365 WeakPolarHBondContact CA-SG 3.25Å; C258-C365 HydrophobicContact CB-CB 3.69Å; C258-C365 WeakPolarHBondContact CB-SG 3.26Å; C258-C365 WeakPolarHBondContact SG-CB 3.15Å; C258-C365 CovalentContact SG-SG 2.03Å; C258-C365 PolarHBondContact SG-SG 2.87Å
259P85.7Confident86.8Confident27 Ų2763.1 Ų63.118%0.17534%0.337CS..PPolyproline II helixtrans-53.6141.2175.2-26.733.9000111.2Y256 P340 E362 F366Y256-P259 HydrophobicContact CE1-CG 4.19Å; P259-P340 HydrophobicContact CB-CB 3.79Å; P259-P340 HydrophobicContact CB-CG 4.41Å; P259-P340 HydrophobicContact CG-CB 4.04Å; P259-P340 HydrophobicContact CG-CG 4.33Å; P259-E362 HydrophobicContact CG-CG 3.79Å; P259-F366 HydrophobicContact CB-CZ 4.11Å; P259-F366 HydrophobicContact CG-CE2 4.27Å; P259-F366 HydrophobicContact CG-CZ 4.23Å; P259-F366 WeakPolarHBondContact O-CZ 3.3Å
260K85.2Confident87.9Confident193 Ų19364.4 Ų64.484%0.83935%0.346SS*.PPolyproline II helixtrans-67163175.2-66.5-173.8179-177.90110.9C258 A262 Q344C258-K260 PolarHBondContact O-N 3.31Å; K260-A262 PolarHBondContact O-N 2.7Å; K260-Q344 PolarHBondContact O-NE2 3.45Å
261A77.7Confident88.7Confident92 Ų9265.2 Ų65.276%0.7635%0.348SS*.PPolyproline II helixtrans-46.8122.3170.900000111.1
262A81.9Confident89.3Confident50 Ų5064.9 Ų64.941%0.41335%0.346SS..  trans-130.5128.7176.300000108.4K260 A341K260-A262 PolarHBondContact O-N 2.7Å; A262-A341 HydrophobicContact CB-CB 4Å; A262-A341 WeakPolarHBondContact O-CB 3.4Å
263N89.7Confident90Very high161 Ų16168 Ų6886%0.86136%0.361SS*.PPolyproline II helixtrans-75.7142.1176.4-68.6-13.8000109.7
264L95.4Very high90.5Very high21 Ų2169 Ų6911%0.1137%0.366CS..PPolyproline II helixtrans-68.7150.7166.2-69.4173.1000109.3Q269 V272 P338 A341 L342 H345L264-Q269 HydrophobicContact CB-CB 4.14Å; L264-V272 HydrophobicContact CD1-CB 4.45Å; L264-V272 HydrophobicContact CD1-CG2 4.41Å; L264-P338 HydrophobicContact CD2-CG 4.07Å; L264-A341 HydrophobicContact CD2-CB 3.57Å; L264-A341 HydrophobicContact CG-CB 4.16Å; L264-L342 HydrophobicContact CD1-CD2 4.38Å; L264-L342 HydrophobicContact CD2-CD2 3.79Å; L264-L342 HydrophobicContact CD2-CG 3.91Å; L264-H345 HydrophobicContact CD1-CB 4.33Å
265T95.9Very high91Very high80 Ų8074.6 Ų74.649%0.49140%0.402SS..PPolyproline II helixtrans-65.6157.7165.467.40000109E267 Y268 Q269T265-E267 PolarHBondContact O-N 3.47Å; T265-E267 VanDerWaalsContact O-N 3.13Å; T265-Y268 PolarHBondContact O-N 2.66Å; T265-Y268 VanDerWaalsContact O-N 3.11Å; T265-Y268 WeakPolarHBondContact OG1-CD2 3.47Å; T265-Q269 WeakPolarHBondContact O-CB 3.41Å; T265-Q269 PolarHBondContact O-N 2.5Å
266Y96.6Very high91.8Very high185 Ų18578.2 Ų78.273%0.72543%0.429SS*.Hα-helixtrans-50.7-40178.4178.4-100.5000112.7Q269 N270Y266-Q269 PolarHBondContact O-N 3.24Å; Y266-N270 VanDerWaalsContact O-CB 3.3Å; Y266-N270 WeakPolarHBondContact O-CB 3.49Å; Y266-N270 PolarHBondContact O-N 3.03Å
267E97Very high92.7Very high117 Ų11775.9 Ų75.955%0.54742%0.421SS..Hα-helixtrans-60.3-52.2177.6-173.3-168.5176.400112.8T265 Q269 F271 K332T265-E267 PolarHBondContact O-N 3.47Å; T265-E267 VanDerWaalsContact O-N 3.13Å; E267-Q269 VanDerWaalsContact C-N 3.35Å; E267-F271 WeakPolarHBondContact O-CB 3.41Å; E267-F271 PolarHBondContact O-N 3.02Å; E267-F271 VanDerWaalsContact O-N 3.13Å; E267-K332 VanDerWaalsContact CD-NZ 3.3Å; E267-K332 WeakPolarHBondContact OE1-CE 3.45Å; E267-K332 IonicContact OE1-NZ 2.89Å; E267-K332 PolarHBondContact OE1-NZ 2.89Å; E267-K332 IonicContact OE2-NZ 3.13Å
268Y97.8Very high93.5Very high18 Ų1880.5 Ų80.57%0.07143%0.433CS..Hα-helixtrans-67.9-37.6178.1-77.4-74.2000111.8T265 F271 V272 V315 K332 D334 P338 L342T265-Y268 PolarHBondContact O-N 2.66Å; T265-Y268 VanDerWaalsContact O-N 3.11Å; T265-Y268 WeakPolarHBondContact OG1-CD2 3.47Å; Y268-F271 PolarHBondContact O-N 3.48Å; Y268-V272 VanDerWaalsContact O-CB 3.26Å; Y268-V272 WeakPolarHBondContact O-CB 3.31Å; Y268-V272 VanDerWaalsContact O-CG2 3.23Å; Y268-V272 WeakPolarHBondContact O-CG2 2.99Å; Y268-V272 PolarHBondContact O-N 3.48Å; Y268-V315 HydrophobicContact CE1-CG1 3.97Å; Y268-K332 HydrophobicContact CD1-CD 3.97Å; Y268-K332 HydrophobicContact CE1-CD 3.83Å; Y268-K332 HydrophobicContact CE1-CG 4.43Å; Y268-D334 VanDerWaalsContact CZ-OD2 3.29Å; Y268-D334 PolarHBondContact OH-OD2 2.71Å; Y268-P338 HydrophobicContact CD1-CG 4.4Å; Y268-P338 HydrophobicContact CD2-CG 3.62Å; Y268-P338 HydrophobicContact CE1-CG 4.35Å; Y268-P338 HydrophobicContact CE2-CG 3.58Å; Y268-P338 HydrophobicContact CG-CG 4.06Å; Y268-L342 HydrophobicContact CD1-CD2 4.2Å
269Q97.6Very high94.1Very high78 Ų7878.1 Ų78.136%0.36442%0.417SS..Hα-helixtrans-61.2-52178.6-173.6171.7600110.6L264 T265 Y266 E267 F271 V272 E273L264-Q269 HydrophobicContact CB-CB 4.14Å; T265-Q269 WeakPolarHBondContact O-CB 3.41Å; T265-Q269 PolarHBondContact O-N 2.5Å; Y266-Q269 PolarHBondContact O-N 3.24Å; E267-Q269 VanDerWaalsContact C-N 3.35Å; Q269-F271 VanDerWaalsContact C-N 3.28Å; Q269-F271 PolarHBondContact O-N 2.77Å; Q269-V272 PolarHBondContact O-N 3.09Å; Q269-E273 HydrophobicContact CG-CG 4.13Å; Q269-E273 WeakPolarHBondContact CG-OE1 3.04Å; Q269-E273 WeakPolarHBondContact CG-OE2 3.39Å; Q269-E273 PolarHBondContact NE2-OE1 3.17Å; Q269-E273 PolarHBondContact NE2-OE2 2.96Å; Q269-E273 VanDerWaalsContact O-CB 3.3Å; Q269-E273 WeakPolarHBondContact O-CB 3.3Å; Q269-E273 WeakPolarHBondContact O-CG 3.49Å; Q269-E273 PolarHBondContact O-N 2.98Å
270N97.5Very high94.7Very high104 Ų10476.9 Ų76.956%0.55641%0.409SS*.Hα-helixtrans-60-37.9178.4-171.846.8000112.3Y266Y266-N270 VanDerWaalsContact O-CB 3.3Å; Y266-N270 WeakPolarHBondContact O-CB 3.49Å; Y266-N270 PolarHBondContact O-N 3.03Å
271F98.2Very high95.3Very high28 Ų2867.7 Ų67.712%0.12337%0.369CS..Hα-helixtrans-67.5-44.2176-178.9-95.9000112.8E267 Y268 Q269 R313 V315 N330 K332E267-F271 WeakPolarHBondContact O-CB 3.41Å; E267-F271 PolarHBondContact O-N 3.02Å; E267-F271 VanDerWaalsContact O-N 3.13Å; Y268-F271 PolarHBondContact O-N 3.48Å; Q269-F271 VanDerWaalsContact C-N 3.28Å; Q269-F271 PolarHBondContact O-N 2.77Å; F271-R313 HydrophobicContact CD1-CB 4.28Å; F271-R313 HydrophobicContact CE1-CB 3.78Å; F271-R313 HydrophobicContact CE1-CG 4.44Å; F271-R313 HydrophobicContact CZ-CB 4.22Å; F271-R313 WeakPolarHBondContact O-CD 3.43Å; F271-R313 VanDerWaalsContact O-CG 3.26Å; F271-R313 WeakPolarHBondContact O-CG 3.23Å; F271-V315 HydrophobicContact CD1-CG2 3.92Å; F271-V315 HydrophobicContact CE1-CG2 3.65Å; F271-N330 VanDerWaalsContact CZ-O 3.26Å; F271-N330 WeakPolarHBondContact CZ-O 3.31Å; F271-K332 HydrophobicContact CB-CD 4.49Å; F271-K332 HydrophobicContact CD1-CB 4.1Å; F271-K332 HydrophobicContact CD1-CD 4.38Å; F271-K332 HydrophobicContact CD2-CB 4.14Å; F271-K332 HydrophobicContact CE1-CB 3.69Å; F271-K332 HydrophobicContact CE2-CB 3.73Å; F271-K332 HydrophobicContact CG-CB 4.3Å; F271-K332 HydrophobicContact CG-CD 4.22Å; F271-K332 HydrophobicContact CZ-CB 3.47Å; F271-K332 VanDerWaalsContact CZ-CB 3.47Å
272V97.9Very high96.3Very high0 Ų063.3 Ų63.30%033%0.332CS..Hα-helixtrans-76.7-32.8-175.1165.40000112.5L264 Y268 Q269 D274 T280 L342 H345 R347L264-V272 HydrophobicContact CD1-CB 4.45Å; L264-V272 HydrophobicContact CD1-CG2 4.41Å; Y268-V272 VanDerWaalsContact O-CB 3.26Å; Y268-V272 WeakPolarHBondContact O-CB 3.31Å; Y268-V272 VanDerWaalsContact O-CG2 3.23Å; Y268-V272 WeakPolarHBondContact O-CG2 2.99Å; Y268-V272 PolarHBondContact O-N 3.48Å; Q269-V272 PolarHBondContact O-N 3.09Å; V272-D274 VanDerWaalsContact C-N 3.31Å; V272-D274 PolarHBondContact O-N 3.11Å; V272-T280 WeakPolarHBondContact CG1-OG1 3.46Å; V272-T280 HydrophobicContact CG2-CG2 4.07Å; V272-L342 HydrophobicContact CG2-CD2 3.88Å; V272-H345 HydrophobicContact CG1-CB 4.49Å; V272-H345 VanDerWaalsContact CG1-ND1 3.26Å; V272-H345 WeakPolarHBondContact CG1-ND1 3.31Å; V272-R347 HydrophobicContact CG1-CB 3.83Å; V272-R347 HydrophobicContact CG1-CG 4.34Å
273E97.6Very high97.1Very high83 Ų8360.9 Ų60.939%0.38831%0.313SS..SBendtrans-85.40.5-175-70.8-178.5171.700114.3Q269 P275 H345 R347Q269-E273 HydrophobicContact CG-CG 4.13Å; Q269-E273 WeakPolarHBondContact CG-OE1 3.04Å; Q269-E273 WeakPolarHBondContact CG-OE2 3.39Å; Q269-E273 PolarHBondContact NE2-OE1 3.17Å; Q269-E273 PolarHBondContact NE2-OE2 2.96Å; Q269-E273 VanDerWaalsContact O-CB 3.3Å; Q269-E273 WeakPolarHBondContact O-CB 3.3Å; Q269-E273 WeakPolarHBondContact O-CG 3.49Å; Q269-E273 PolarHBondContact O-N 2.98Å; E273-P275 WeakPolarHBondContact O-CD 3.35Å; E273-P275 VanDerWaalsContact O-N 3.14Å; E273-H345 IonicContact OE1-NE2 3.68Å; E273-H345 PolarHBondContact OE1-NE2 2.98Å; E273-R347 PolarHBondContact O-NH2 3.38Å
274D97Very high97.5Very high39 Ų3953.3 Ų53.321%0.20927%0.272CS..  trans-45.3119.7-179.1-171.1-57.1000112.3V272 S276 S277 R313 R347V272-D274 VanDerWaalsContact C-N 3.31Å; V272-D274 PolarHBondContact O-N 3.11Å; D274-S276 PolarHBondContact O-N 3.15Å; D274-S276 WeakPolarHBondContact OD1-CA 3.36Å; D274-S276 VanDerWaalsContact OD1-CB 3.3Å; D274-S276 WeakPolarHBondContact OD1-CB 3.46Å; D274-S276 PolarHBondContact OD1-N 3.37Å; D274-S276 PolarHBondContact OD1-OG 2.81Å; D274-S277 WeakPolarHBondContact O-CB 3.22Å; D274-S277 PolarHBondContact O-N 3.45Å; D274-R313 HydrophobicContact CB-CG 4.41Å; D274-R313 IonicContact OD2-CZ 2.63Å; D274-R313 IonicContact OD2-NE 2.77Å; D274-R313 IonicContact OD2-NH2 3.76Å; D274-R313 PolarHBondContact OD2-NH2 2.84Å; D274-R347 PolarHBondContact O-NH2 2.79Å
275P96.5Very high97.5Very high122 Ų12252.6 Ų52.679%0.79227%0.268SS*.THydrogen-bonded Turntrans-59.5-29.4-176.7-26.435000114.8E273 S277E273-P275 WeakPolarHBondContact O-CD 3.35Å; E273-P275 VanDerWaalsContact O-N 3.14Å; P275-S277 VanDerWaalsContact C-N 3.26Å; P275-S277 PolarHBondContact O-N 2.91Å
276S96.2Very high97.1Very high94 Ų9449.4 Ų49.466%0.65725%0.251SS*.THydrogen-bonded Turntrans-75-15.417971.80000113.2D274D274-S276 PolarHBondContact O-N 3.15Å; D274-S276 WeakPolarHBondContact OD1-CA 3.36Å; D274-S276 VanDerWaalsContact OD1-CB 3.3Å; D274-S276 WeakPolarHBondContact OD1-CB 3.46Å; D274-S276 PolarHBondContact OD1-N 3.37Å; D274-S276 PolarHBondContact OD1-OG 2.81Å
277S97.8Very high96.4Very high8 Ų844.6 Ų44.66%0.05624%0.235CC..  trans-79.7136-177.6-171.40000113D274 P275 G279 R313 R347D274-S277 WeakPolarHBondContact O-CB 3.22Å; D274-S277 PolarHBondContact O-N 3.45Å; P275-S277 VanDerWaalsContact C-N 3.26Å; P275-S277 PolarHBondContact O-N 2.91Å; S277-G279 PolarHBondContact O-N 3.45Å; S277-G279 PolarHBondContact OG-N 2.98Å; S277-G279 VanDerWaalsContact OG-N 3.09Å; S277-G279 PolarHBondContact OG-O 3.15Å; S277-R313 WeakPolarHBondContact OG-CG 3.42Å; S277-R313 PolarHBondContact OG-N 3.21Å; S277-R347 PolarHBondContact O-NH1 3.2Å; S277-R347 VanDerWaalsContact O-NH1 3.12Å
278K97.8Very high95.6Very high140 Ų14042.1 Ų42.161%0.60923%0.225SC*.SBendtrans-73.7-9.2168.3-65.2-168.9-175.9179.80113.1Q311 Y312K278-Q311 WeakPolarHBondContact CB-O 3.12Å; K278-Q311 HydrophobicContact CD-CB 4.17Å; K278-Q311 HydrophobicContact CD-CG 3.8Å; K278-Q311 HydrophobicContact CG-CB 4.24Å; K278-Q311 HydrophobicContact CG-CG 4.28Å; K278-Q311 PolarHBondContact N-O 2.87Å; K278-Y312 HydrophobicContact CB-CD1 3.98Å; K278-Y312 HydrophobicContact CB-CE1 3.56Å
279G98.2Very high95Very high1 Ų141.7 Ų41.71%0.0123%0.226CC..  trans144.8178.3179.100000112.8S277 Y312 R313 R347S277-G279 PolarHBondContact O-N 3.45Å; S277-G279 PolarHBondContact OG-N 2.98Å; S277-G279 VanDerWaalsContact OG-N 3.09Å; S277-G279 PolarHBondContact OG-O 3.15Å; G279-Y312 WeakPolarHBondContact O-CA 3.09Å; G279-Y312 WeakPolarHBondContact O-CD1 3.44Å; G279-R313 PolarHBondContact O-N 2.93Å; G279-R347 CarbonylContact C-O 3.58Å; G279-R347 VanDerWaalsContact CA-O 3.26Å; G279-R347 WeakPolarHBondContact CA-O 3.49Å
280T98.7Very high94.6Very high0 Ų039.9 Ų39.90%022%0.219CC..EExtended strand (participates in β ladder)trans-106.8129.9-176.7-58.10000111.4V272 V282 R313 V315 R347 T348 V349V272-T280 WeakPolarHBondContact CG1-OG1 3.46Å; V272-T280 HydrophobicContact CG2-CG2 4.07Å; T280-V282 HydrophobicContact CG2-CG2 4.08Å; T280-R313 CarbonylContact C-O 3.57Å; T280-R313 WeakPolarHBondContact CA-O 3.43Å; T280-V315 HydrophobicContact CG2-CG2 4.14Å; T280-R347 PolarHBondContact N-O 3.29Å; T280-T348 WeakPolarHBondContact O-CA 3.34Å; T280-V349 WeakPolarHBondContact O-CG2 3.49Å; T280-V349 PolarHBondContact O-N 3.16Å
281I98.8Very high94.4Very high0 Ų035.2 Ų35.20%019%0.193CC..EExtended strand (participates in β ladder)trans-100.7123.9168.3-56.8176.2000107.2L309 Y312 R313 I314 V315 V349 L350 I352 I409 L413I281-L309 HydrophobicContact CD1-CD1 4.1Å; I281-Y312 HydrophobicContact CD1-CD2 4.38Å; I281-Y312 HydrophobicContact CD1-CG 4.06Å; I281-Y312 HydrophobicContact CG1-CD1 4.47Å; I281-Y312 HydrophobicContact CG1-CG 4.4Å; I281-R313 PolarHBondContact N-O 3.44Å; I281-I314 HydrophobicContact CB-CG1 4.27Å; I281-I314 HydrophobicContact CB-CG2 4.49Å; I281-I314 HydrophobicContact CD1-CG1 4.44Å; I281-I314 CarbonylContact O-C 3.49Å; I281-I314 WeakPolarHBondContact O-CA 3.39Å; I281-V315 PolarHBondContact O-N 2.96Å; I281-V349 HydrophobicContact CG1-CG2 4.47Å; I281-L350 WeakPolarHBondContact CA-O 3.45Å; I281-L350 HydrophobicContact CD1-CD2 4.48Å; I281-L350 HydrophobicContact CG1-CB 4.25Å; I281-L350 HydrophobicContact CG1-CD2 4.49Å; I281-L350 HydrophobicContact CG2-CB 4.26Å; I281-L350 HydrophobicContact CG2-CD2 4.02Å; I281-L350 HydrophobicContact CG2-CG 4.21Å; I281-I352 HydrophobicContact CG2-CD1 3.74Å; I281-I352 HydrophobicContact CG2-CG1 3.94Å; I281-I409 HydrophobicContact CD1-CG2 4.03Å; I281-L413 HydrophobicContact CD1-CD1 4.2Å
282V98.7Very high94Very high0 Ų040.6 Ų40.60%022%0.219CC..EExtended strand (participates in β ladder)trans-105.8130.9177.2-178.90000108.7T280 V315 I337 L339 L342 T348 L350 F351 I352T280-V282 HydrophobicContact CG2-CG2 4.08Å; V282-V315 CarbonylContact C-O 3.48Å; V282-V315 WeakPolarHBondContact CA-O 3.35Å; V282-I337 HydrophobicContact CG1-CD1 3.71Å; V282-L339 HydrophobicContact CG1-CD1 3.69Å; V282-L342 HydrophobicContact CG1-CD1 4.4Å; V282-L342 HydrophobicContact CG2-CB 3.95Å; V282-T348 HydrophobicContact CG2-CG2 3.83Å; V282-L350 PolarHBondContact N-O 2.79Å; V282-F351 HydrophobicContact CB-CD2 4.12Å; V282-F351 HydrophobicContact CG1-CD2 4.1Å; V282-F351 HydrophobicContact CG1-CE2 4.24Å; V282-F351 CarbonylContact O-C 3.58Å; V282-F351 WeakPolarHBondContact O-CA 3.36Å; V282-F351 WeakPolarHBondContact O-CD2 3.23Å; V282-I352 PolarHBondContact O-N 2.94Å
283F98.5Very high93.6Very high0 Ų041.3 Ų41.30%023%0.226CC..EExtended strand (participates in β ladder)trans-118.8112.3175.5-170.1159.9000109.3F285 W291 I302 F306 V315 W316 Q317 I352 F405F283-F285 HydrophobicContact CD2-CD1 4.13Å; F283-F285 HydrophobicContact CD2-CE1 4.09Å; F283-F285 AromaticContact CE2-CD1 3.5Å; F283-F285 HydrophobicContact CE2-CD1 3.5Å; F283-F285 VanDerWaalsContact CE2-CD1 3.5Å; F283-F285 AromaticContact CE2-CD2 3.94Å; F283-F285 HydrophobicContact CE2-CD2 3.94Å; F283-F285 AromaticContact CE2-CE1 3.22Å; F283-F285 HydrophobicContact CE2-CE1 3.22Å; F283-F285 AromaticContact CE2-CE2 3.67Å; F283-F285 HydrophobicContact CE2-CE2 3.67Å; F283-F285 AromaticContact CE2-CG 3.87Å; F283-F285 HydrophobicContact CE2-CG 3.87Å; F283-F285 AromaticContact CE2-CZ 3.3Å; F283-F285 HydrophobicContact CE2-CZ 3.3Å; F283-F285 HydrophobicContact CZ-CD1 4.49Å; F283-F285 AromaticContact CZ-CE1 3.86Å; F283-F285 HydrophobicContact CZ-CE1 3.86Å; F283-F285 AromaticContact CZ-CE2 3.86Å; F283-F285 HydrophobicContact CZ-CE2 3.86Å; F283-F285 AromaticContact CZ-CZ 3.49Å; F283-F285 HydrophobicContact CZ-CZ 3.49Å; F283-F285 VanDerWaalsContact CZ-CZ 3.49Å; F283-W291 HydrophobicContact CD2-CZ2 4.34Å; F283-W291 HydrophobicContact CE1-CH2 4.16Å; F283-W291 HydrophobicContact CE1-CZ2 4.46Å; F283-W291 AromaticContact CE2-CH2 3.85Å; F283-W291 HydrophobicContact CE2-CH2 3.85Å; F283-W291 AromaticContact CE2-CZ2 3.56Å; F283-W291 HydrophobicContact CE2-CZ2 3.56Å; F283-W291 AromaticContact CZ-CH2 3.47Å; F283-W291 HydrophobicContact CZ-CH2 3.47Å; F283-W291 VanDerWaalsContact CZ-CH2 3.47Å; F283-W291 AromaticContact CZ-CZ2 3.7Å; F283-W291 HydrophobicContact CZ-CZ2 3.7Å; F283-I302 HydrophobicContact CD1-CG2 4.24Å; F283-I302 HydrophobicContact CE1-CD1 3.94Å; F283-I302 HydrophobicContact CE1-CG1 4.37Å; F283-I302 HydrophobicContact CE1-CG2 3.69Å; F283-I302 HydrophobicContact CZ-CD1 4.03Å; F283-F306 HydrophobicContact CB-CZ 4.4Å; F283-F306 AromaticContact CD1-CE2 3.82Å; F283-F306 HydrophobicContact CD1-CE2 3.82Å; F283-F306 AromaticContact CD1-CZ 3.6Å; F283-F306 HydrophobicContact CD1-CZ 3.6Å; F283-F306 HydrophobicContact CE1-CZ 4.38Å; F283-F306 HydrophobicContact CG-CZ 4.49Å; F283-V315 PolarHBondContact N-O 2.79Å; F283-W316 HydrophobicContact CB-CB 4.32Å; F283-W316 HydrophobicContact CB-CG 4.17Å; F283-W316 AromaticContact CD1-CD1 3.78Å; F283-W316 HydrophobicContact CD1-CD2 4.38Å; F283-W316 HydrophobicContact CD1-CG 4.19Å; F283-W316 AromaticContact CD1-NE1 3.76Å; F283-W316 AromaticContact CD2-CD1 3.99Å; F283-W316 AromaticContact CE1-NE1 3.99Å; F283-W316 AromaticContact CG-CD1 3.58Å; F283-W316 HydrophobicContact CG-CG 4.25Å; F283-W316 AromaticContact CG-NE1 3.88Å; F283-Q317 WeakPolarHBondContact O-CB 3.45Å; F283-Q317 PolarHBondContact O-N 3.37Å; F283-I352 WeakPolarHBondContact CA-O 3.41Å; F283-I352 HydrophobicContact CB-CB 4.1Å; F283-I352 HydrophobicContact CD1-CB 4.3Å; F283-I352 HydrophobicContact CD1-CD1 4.28Å; F283-I352 HydrophobicContact CD1-CG2 4.04Å; F283-I352 HydrophobicContact CD2-CB 4.19Å; F283-I352 HydrophobicContact CD2-CG2 3.98Å; F283-I352 HydrophobicContact CE1-CG2 4.02Å; F283-I352 HydrophobicContact CE2-CG2 4.04Å; F283-I352 HydrophobicContact CG-CB 3.93Å; F283-I352 HydrophobicContact CG-CG2 3.96Å; F283-I352 HydrophobicContact CZ-CG2 4Å; F283-F405 HydrophobicContact CD1-CZ 4.12Å; F283-F405 HydrophobicContact CE1-CE2 4.14Å; F283-F405 AromaticContact CE1-CZ 3.66Å; F283-F405 HydrophobicContact CE1-CZ 3.66Å
284S97.7Very high93.4Very high1 Ų137.9 Ų37.91%0.00721%0.212CC..EExtended strand (participates in β ladder)trans-141.1132.5170.3169.20000113.9G286 Q317 I352 T353S284-G286 PolarHBondContact OG-N 3.38Å; S284-Q317 PolarHBondContact OG-OE1 3.49Å; S284-I352 PolarHBondContact N-O 3.28Å; S284-T353 WeakPolarHBondContact O-CA 3.4Å; S284-T353 PolarHBondContact O-OG1 3.4Å
285F95Very high93.3Very high6 Ų636.7 Ų36.73%0.02621%0.206CC..  trans-105.414.7172.9-72.3-8.8000114.1W95 F283 A289 W291 H354 I373 L375W95-F285 AromaticContact CH2-CD2 3.63Å; W95-F285 HydrophobicContact CH2-CD2 3.63Å; W95-F285 AromaticContact CH2-CE2 3.81Å; W95-F285 HydrophobicContact CH2-CE2 3.81Å; W95-F285 HydrophobicContact CZ2-CD2 4.5Å; W95-F285 HydrophobicContact CZ3-CD2 4.21Å; W95-F285 AromaticContact CZ3-CE2 3.94Å; W95-F285 HydrophobicContact CZ3-CE2 3.94Å; F283-F285 HydrophobicContact CD2-CD1 4.13Å; F283-F285 HydrophobicContact CD2-CE1 4.09Å; F283-F285 AromaticContact CE2-CD1 3.5Å; F283-F285 HydrophobicContact CE2-CD1 3.5Å; F283-F285 VanDerWaalsContact CE2-CD1 3.5Å; F283-F285 AromaticContact CE2-CD2 3.94Å; F283-F285 HydrophobicContact CE2-CD2 3.94Å; F283-F285 AromaticContact CE2-CE1 3.22Å; F283-F285 HydrophobicContact CE2-CE1 3.22Å; F283-F285 AromaticContact CE2-CE2 3.67Å; F283-F285 HydrophobicContact CE2-CE2 3.67Å; F283-F285 AromaticContact CE2-CG 3.87Å; F283-F285 HydrophobicContact CE2-CG 3.87Å; F283-F285 AromaticContact CE2-CZ 3.3Å; F283-F285 HydrophobicContact CE2-CZ 3.3Å; F283-F285 HydrophobicContact CZ-CD1 4.49Å; F283-F285 AromaticContact CZ-CE1 3.86Å; F283-F285 HydrophobicContact CZ-CE1 3.86Å; F283-F285 AromaticContact CZ-CE2 3.86Å; F283-F285 HydrophobicContact CZ-CE2 3.86Å; F283-F285 AromaticContact CZ-CZ 3.49Å; F283-F285 HydrophobicContact CZ-CZ 3.49Å; F283-F285 VanDerWaalsContact CZ-CZ 3.49Å; F285-A289 HydrophobicContact CB-CB 3.41Å; F285-A289 VanDerWaalsContact CB-CB 3.41Å; F285-A289 HydrophobicContact CG-CB 4.48Å; F285-A289 WeakPolarHBondContact O-CB 3.43Å; F285-W291 HydrophobicContact CD2-CH2 4.08Å; F285-W291 AromaticContact CD2-CZ2 3.71Å; F285-W291 HydrophobicContact CD2-CZ2 3.71Å; F285-W291 AromaticContact CE2-CH2 3.85Å; F285-W291 HydrophobicContact CE2-CH2 3.85Å; F285-W291 AromaticContact CE2-CZ2 3.94Å; F285-W291 HydrophobicContact CE2-CZ2 3.94Å; F285-W291 HydrophobicContact CG-CZ2 4.38Å; F285-H354 HydrophobicContact CB-CB 4.22Å; F285-H354 HydrophobicContact CD1-CB 3.73Å; F285-H354 HydrophobicContact CE1-CB 4.27Å; F285-H354 HydrophobicContact CG-CB 4.05Å; F285-H354 PolarHBondContact O-CD2 3.03Å; F285-H354 PolarHBondContact O-CE1 3.34Å; F285-H354 PolarHBondContact O-ND1 3.31Å; F285-H354 PolarHBondContact O-NE2 3.01Å; F285-I373 HydrophobicContact CE1-CB 4.12Å; F285-I373 HydrophobicContact CZ-CB 3.81Å; F285-I373 HydrophobicContact CZ-CD1 4.35Å; F285-I373 HydrophobicContact CZ-CG2 4.13Å; F285-L375 HydrophobicContact CB-CD1 4.33Å; F285-L375 HydrophobicContact CD2-CD1 4.06Å; F285-L375 HydrophobicContact CD2-CD2 4.13Å; F285-L375 HydrophobicContact CD2-CG 4.35Å; F285-L375 HydrophobicContact CE2-CD2 4.03Å; F285-L375 HydrophobicContact CG-CD1 4.43Å
286G88.6Confident93.2Very high13 Ų1333.6 Ų33.613%0.13419%0.185CC..  trans76.3-156171.200000114.9S284 Q317S284-G286 PolarHBondContact OG-N 3.38Å; G286-Q317 PolarHBondContact O-NE2 2.94Å
287H82.1Confident93.1Very high84 Ų8435.3 Ų35.339%0.38918%0.183SC..SBendtrans-86.5-26.6-168.8-62.354.3000114.2W336H287-W336 HydrophobicContact CB-CH2 3.95Å; H287-W336 AromaticContact CD2-CH2 3.55Å; H287-W336 AromaticContact CE1-CH2 3.89Å; H287-W336 AromaticContact CE1-CZ3 3.94Å; H287-W336 AromaticContact CG-CH2 3.47Å; H287-W336 VanDerWaalsContact CG-CH2 3.47Å; H287-W336 AromaticContact ND1-CH2 3.7Å; H287-W336 AromaticContact ND1-CZ3 4Å; H287-W336 AromaticContact NE2-CH2 3.88Å
288L80Confident93Very high65 Ų6535.7 Ų35.734%0.3418%0.184SC..SBendtrans-95.8-6.3-172.5-65.7-179.9000113.2I86 Q91 F376I86-L288 HydrophobicContact CD1-CB 3.83Å; I86-L288 HydrophobicContact CD1-CD1 4.26Å; I86-L288 HydrophobicContact CD1-CD2 4.11Å; I86-L288 HydrophobicContact CD1-CG 4.28Å; Q91-L288 PolarHBondContact NE2-O 3.06Å; Q91-L288 PolarHBondContact OE1-O 2.99Å; L288-F376 HydrophobicContact CB-CZ 4.3Å; L288-F376 HydrophobicContact CD1-CZ 4.05Å
289A85Confident93Very high10 Ų1029.2 Ų29.28%0.08316%0.156CC..  trans-88.9107.1178.500000109.8W95 F285 L375W95-A289 HydrophobicContact CZ2-CB 4.37Å; F285-A289 HydrophobicContact CB-CB 3.41Å; F285-A289 VanDerWaalsContact CB-CB 3.41Å; F285-A289 HydrophobicContact CG-CB 4.48Å; F285-A289 WeakPolarHBondContact O-CB 3.43Å; A289-L375 HydrophobicContact CB-CD1 3.5Å; A289-L375 VanDerWaalsContact CB-CD1 3.5Å
290D89Confident93Very high40 Ų4034.1 Ų34.121%0.21418%0.178CC..  trans-98.9111.4172.3-17810.4000110.2Q91 W95 Q292 G293 N319Q91-D290 HydrophobicContact CG-CB 4.29Å; W95-D290 PolarHBondContact NE1-O 3.21Å; D290-Q292 PolarHBondContact O-N 2.97Å; D290-Q292 WeakPolarHBondContact OD1-CB 3.36Å; D290-Q292 WeakPolarHBondContact OD1-CG 3.22Å; D290-Q292 PolarHBondContact OD1-N 3.34Å; D290-G293 PolarHBondContact O-N 3.27Å; D290-G293 VanDerWaalsContact O-N 3.13Å; D290-N319 PolarHBondContact OD1-ND2 2.82Å
291W93.4Very high92.9Very high5 Ų534.7 Ų34.72%0.01918%0.184CC..G310 helixtrans-65.9-16.2-179.5-7396.9000113.5W95 F283 F285 G293 A294 I299 I302 W316 Q317 F318 N319W95-W291 AromaticContact CH2-CD2 3.89Å; W95-W291 HydrophobicContact CH2-CD2 3.89Å; W95-W291 AromaticContact CH2-CE3 3.64Å; W95-W291 HydrophobicContact CH2-CE3 3.64Å; W95-W291 AromaticContact CH2-CH2 3.94Å; W95-W291 HydrophobicContact CH2-CH2 3.94Å; W95-W291 HydrophobicContact CH2-CZ2 4.17Å; W95-W291 AromaticContact CH2-CZ3 3.67Å; W95-W291 HydrophobicContact CH2-CZ3 3.67Å; W95-W291 HydrophobicContact CZ2-CD2 4.14Å; W95-W291 HydrophobicContact CZ2-CE3 4.14Å; W95-W291 HydrophobicContact CZ2-CG 4.47Å; W95-W291 HydrophobicContact CZ3-CE3 4.34Å; W95-W291 HydrophobicContact CZ3-CH2 4.44Å; W95-W291 HydrophobicContact CZ3-CZ3 4.07Å; F283-W291 HydrophobicContact CD2-CZ2 4.34Å; F283-W291 HydrophobicContact CE1-CH2 4.16Å; F283-W291 HydrophobicContact CE1-CZ2 4.46Å; F283-W291 AromaticContact CE2-CH2 3.85Å; F283-W291 HydrophobicContact CE2-CH2 3.85Å; F283-W291 AromaticContact CE2-CZ2 3.56Å; F283-W291 HydrophobicContact CE2-CZ2 3.56Å; F283-W291 AromaticContact CZ-CH2 3.47Å; F283-W291 HydrophobicContact CZ-CH2 3.47Å; F283-W291 VanDerWaalsContact CZ-CH2 3.47Å; F283-W291 AromaticContact CZ-CZ2 3.7Å; F283-W291 HydrophobicContact CZ-CZ2 3.7Å; F285-W291 HydrophobicContact CD2-CH2 4.08Å; F285-W291 AromaticContact CD2-CZ2 3.71Å; F285-W291 HydrophobicContact CD2-CZ2 3.71Å; F285-W291 AromaticContact CE2-CH2 3.85Å; F285-W291 HydrophobicContact CE2-CH2 3.85Å; F285-W291 AromaticContact CE2-CZ2 3.94Å; F285-W291 HydrophobicContact CE2-CZ2 3.94Å; F285-W291 HydrophobicContact CG-CZ2 4.38Å; W291-G293 PolarHBondContact O-N 3Å; W291-A294 HydrophobicContact CE3-CB 4.04Å; W291-A294 WeakPolarHBondContact O-CB 3.27Å; W291-A294 PolarHBondContact O-N 3.5Å; W291-A294 VanDerWaalsContact O-N 3.16Å; W291-I299 HydrophobicContact CE3-CG1 4.16Å; W291-I299 HydrophobicContact CZ3-CG1 4.45Å; W291-I302 HydrophobicContact CH2-CD1 3.84Å; W291-I302 HydrophobicContact CZ3-CD1 3.95Å; W291-W316 AromaticContact CE2-NE1 3.67Å; W291-W316 HydrophobicContact CE3-CZ2 4.29Å; W291-W316 AromaticContact CH2-CZ2 3.74Å; W291-W316 HydrophobicContact CH2-CZ2 3.74Å; W291-W316 AromaticContact CH2-NE1 3.75Å; W291-W316 AromaticContact CZ2-CE2 3.96Å; W291-W316 HydrophobicContact CZ2-CZ2 4.06Å; W291-W316 AromaticContact CZ2-NE1 3.23Å; W291-W316 AromaticContact CZ3-CZ2 3.86Å; W291-W316 HydrophobicContact CZ3-CZ2 3.86Å; W291-Q317 PolarHBondContact NE1-O 2.8Å; W291-F318 HydrophobicContact CB-CD2 3.72Å; W291-F318 HydrophobicContact CB-CE2 3.62Å; W291-F318 HydrophobicContact CB-CZ 4.41Å; W291-F318 AromaticContact CD1-CD2 3.86Å; W291-F318 AromaticContact CD2-CD2 3.46Å; W291-F318 HydrophobicContact CD2-CD2 3.46Å; W291-F318 VanDerWaalsContact CD2-CD2 3.46Å; W291-F318 AromaticContact CD2-CE2 3.8Å; W291-F318 HydrophobicContact CD2-CE2 3.8Å; W291-F318 AromaticContact CE2-CD2 3.94Å; W291-F318 AromaticContact CE3-CD2 3.87Å; W291-F318 HydrophobicContact CE3-CD2 3.87Å; W291-F318 AromaticContact CE3-CE2 3.8Å; W291-F318 HydrophobicContact CE3-CE2 3.8Å; W291-F318 AromaticContact CG-CD2 3.4Å; W291-F318 HydrophobicContact CG-CD2 3.4Å; W291-F318 AromaticContact CG-CE2 3.75Å; W291-F318 HydrophobicContact CG-CE2 3.75Å; W291-F318 HydrophobicContact CG-CG 4.3Å; W291-N319 WeakPolarHBondContact CB-OD1 3.49Å; W291-N319 VanDerWaalsContact CD1-OD1 3.27Å; W291-N319 PolarHBondContact N-OD1 3.17Å
292Q90Very high92.9Very high142 Ų14234.8 Ų34.866%0.66418%0.184SC*.G310 helixtrans-65.6-26.5173.2-60.7-178.920.900112.6D290D290-Q292 PolarHBondContact O-N 2.97Å; D290-Q292 WeakPolarHBondContact OD1-CB 3.36Å; D290-Q292 WeakPolarHBondContact OD1-CG 3.22Å; D290-Q292 PolarHBondContact OD1-N 3.34Å
293G88.7Confident92.8Very high15 Ų1535.2 Ų35.216%0.15519%0.187CC..G310 helixtrans-85.1-6.517500000114.4D290 W291D290-G293 PolarHBondContact O-N 3.27Å; D290-G293 VanDerWaalsContact O-N 3.13Å; W291-G293 PolarHBondContact O-N 3Å
294A93.2Very high92.8Very high11 Ų1136.4 Ų36.49%0.09120%0.197CC..SBendtrans-77.6141.2-176.800000111.5W95 W291 V296 I299W95-A294 HydrophobicContact CD2-CB 3.62Å; W95-A294 HydrophobicContact CE3-CB 3.79Å; W95-A294 HydrophobicContact CG-CB 4.08Å; W95-A294 HydrophobicContact CH2-CB 4.1Å; W95-A294 HydrophobicContact CZ2-CB 3.98Å; W95-A294 HydrophobicContact CZ3-CB 4.01Å; W291-A294 HydrophobicContact CE3-CB 4.04Å; W291-A294 WeakPolarHBondContact O-CB 3.27Å; W291-A294 PolarHBondContact O-N 3.5Å; W291-A294 VanDerWaalsContact O-N 3.16Å; A294-V296 PolarHBondContact O-N 3.32Å; A294-I299 HydrophobicContact CB-CD1 4.17Å; A294-I299 HydrophobicContact CB-CG1 4.18Å
295P94.3Very high92.8Very high13 Ų1336.4 Ų36.48%0.08420%0.197CC..  trans-55.8136.1170.8-24.632.4000111.9R96 E297 I298 I299R96-P295 HydrophobicContact CG-CG 3.99Å; P295-E297 VanDerWaalsContact CB-OE2 3.24Å; P295-E297 WeakPolarHBondContact CB-OE2 3.46Å; P295-E297 PolarHBondContact O-N 3.49Å; P295-I298 HydrophobicContact CB-CB 4.46Å; P295-I298 HydrophobicContact CB-CD1 4.35Å; P295-I298 HydrophobicContact CB-CG1 4.23Å; P295-I298 HydrophobicContact CG-CD1 4.01Å; P295-I298 HydrophobicContact CG-CG1 4.44Å; P295-I298 WeakPolarHBondContact O-CB 3.5Å; P295-I298 PolarHBondContact O-N 2.93Å; P295-I299 PolarHBondContact O-N 2.68Å
296V94.9Very high93Very high58 Ų5836.2 Ų36.235%0.35220%0.196SC..Hα-helixtrans-59.2-36.1-179.5174.70000110.7A294 I298 I299 Q300 M324A294-V296 PolarHBondContact O-N 3.32Å; V296-I298 VanDerWaalsContact C-N 3.27Å; V296-I298 PolarHBondContact O-N 3.3Å; V296-I299 PolarHBondContact O-N 3.34Å; V296-Q300 HydrophobicContact CG1-CG 4.14Å; V296-Q300 WeakPolarHBondContact O-CB 3.46Å; V296-Q300 WeakPolarHBondContact O-CG 3.38Å; V296-Q300 PolarHBondContact O-N 2.9Å; V296-M324 HydrophobicContact CG2-CE 4.33Å; V296-M324 HydrophobicContact CG2-SD 4.29Å
297E95.3Very high93.4Very high130 Ų13040 Ų4061%0.60721%0.21SC*.Hα-helixtrans-62.1-35.4179.2-53.378.2-170.800111.6P295 A301P295-E297 VanDerWaalsContact CB-OE2 3.24Å; P295-E297 WeakPolarHBondContact CB-OE2 3.46Å; P295-E297 PolarHBondContact O-N 3.49Å; E297-A301 WeakPolarHBondContact O-CB 3.23Å; E297-A301 PolarHBondContact O-N 3.24Å
298I96.1Very high94.2Very high15 Ų1539.8 Ų39.88%0.07721%0.209CC..Hα-helixtrans-71.3-43.7176.5-70.9-177.2000110.5P295 V296 A301 I302 K397 L400P295-I298 HydrophobicContact CB-CB 4.46Å; P295-I298 HydrophobicContact CB-CD1 4.35Å; P295-I298 HydrophobicContact CB-CG1 4.23Å; P295-I298 HydrophobicContact CG-CD1 4.01Å; P295-I298 HydrophobicContact CG-CG1 4.44Å; P295-I298 WeakPolarHBondContact O-CB 3.5Å; P295-I298 PolarHBondContact O-N 2.93Å; V296-I298 VanDerWaalsContact C-N 3.27Å; V296-I298 PolarHBondContact O-N 3.3Å; I298-A301 PolarHBondContact O-N 2.81Å; I298-I302 HydrophobicContact CG2-CD1 3.84Å; I298-I302 WeakPolarHBondContact O-CD1 3.28Å; I298-I302 VanDerWaalsContact O-CG1 3.29Å; I298-I302 WeakPolarHBondContact O-CG1 3.2Å; I298-I302 PolarHBondContact O-N 3.41Å; I298-K397 VanDerWaalsContact CD1-O 3.26Å; I298-K397 WeakPolarHBondContact CD1-O 3.22Å; I298-L400 HydrophobicContact CG2-CD2 4.04Å
299I97.1Very high95Very high4 Ų436.7 Ų36.72%0.02119%0.193CC..Hα-helixtrans-61.7-47.1178.4-62.6172.6000110W291 A294 P295 V296 I302 S303 W316 F318 M324 V325W291-I299 HydrophobicContact CE3-CG1 4.16Å; W291-I299 HydrophobicContact CZ3-CG1 4.45Å; A294-I299 HydrophobicContact CB-CD1 4.17Å; A294-I299 HydrophobicContact CB-CG1 4.18Å; P295-I299 PolarHBondContact O-N 2.68Å; V296-I299 PolarHBondContact O-N 3.34Å; I299-I302 PolarHBondContact O-N 3.01Å; I299-S303 WeakPolarHBondContact O-CB 3.38Å; I299-S303 PolarHBondContact O-N 3.25Å; I299-W316 HydrophobicContact CG2-CH2 4.29Å; I299-F318 HydrophobicContact CD1-CE2 4.11Å; I299-F318 HydrophobicContact CD1-CZ 4.24Å; I299-F318 HydrophobicContact CG1-CE2 4.24Å; I299-F318 HydrophobicContact CG2-CE2 4Å; I299-F318 HydrophobicContact CG2-CZ 4Å; I299-M324 HydrophobicContact CD1-SD 4.47Å; I299-M324 HydrophobicContact CG2-CB 4.15Å; I299-V325 HydrophobicContact CG2-CG1 3.49Å; I299-V325 VanDerWaalsContact CG2-CG1 3.49Å
300Q97.1Very high95.6Very high104 Ų10440.5 Ų40.549%0.48622%0.217SC..Hα-helixtrans-64.6-43.3178.4-72.8177.4-2200112V296 I302 S303 A304V296-Q300 HydrophobicContact CG1-CG 4.14Å; V296-Q300 WeakPolarHBondContact O-CB 3.46Å; V296-Q300 WeakPolarHBondContact O-CG 3.38Å; V296-Q300 PolarHBondContact O-N 2.9Å; Q300-I302 VanDerWaalsContact C-N 3.34Å; Q300-I302 PolarHBondContact O-N 2.97Å; Q300-S303 PolarHBondContact O-N 3.49Å; Q300-A304 WeakPolarHBondContact O-CB 3.29Å; Q300-A304 PolarHBondContact O-N 3.43Å
301A97.6Very high96Very high13 Ų1341.4 Ų41.411%0.10722%0.22CC..Hα-helixtrans-58.7-43.7175.600000112.6E297 I298 A305 E402E297-A301 WeakPolarHBondContact O-CB 3.23Å; E297-A301 PolarHBondContact O-N 3.24Å; I298-A301 PolarHBondContact O-N 2.81Å; A301-A305 WeakPolarHBondContact O-CB 3.17Å; A301-A305 PolarHBondContact O-N 3.14Å; A301-A305 VanDerWaalsContact O-N 3.15Å; A301-E402 HydrophobicContact CB-CB 4.43Å; A301-E402 WeakPolarHBondContact O-CA 3.46Å
302I98.1Very high96.2Very high2 Ų242.4 Ų42.41%0.0122%0.224CC..Hα-helixtrans-64.1-47.1175.7-71.6165.1000110.4F283 W291 I298 I299 Q300 A305 F306 W316 L400 F405F283-I302 HydrophobicContact CD1-CG2 4.24Å; F283-I302 HydrophobicContact CE1-CD1 3.94Å; F283-I302 HydrophobicContact CE1-CG1 4.37Å; F283-I302 HydrophobicContact CE1-CG2 3.69Å; F283-I302 HydrophobicContact CZ-CD1 4.03Å; W291-I302 HydrophobicContact CH2-CD1 3.84Å; W291-I302 HydrophobicContact CZ3-CD1 3.95Å; I298-I302 HydrophobicContact CG2-CD1 3.84Å; I298-I302 WeakPolarHBondContact O-CD1 3.28Å; I298-I302 VanDerWaalsContact O-CG1 3.29Å; I298-I302 WeakPolarHBondContact O-CG1 3.2Å; I298-I302 PolarHBondContact O-N 3.41Å; I299-I302 PolarHBondContact O-N 3.01Å; Q300-I302 VanDerWaalsContact C-N 3.34Å; Q300-I302 PolarHBondContact O-N 2.97Å; I302-A305 PolarHBondContact O-N 3.42Å; I302-F306 HydrophobicContact CG2-CD2 4.01Å; I302-F306 HydrophobicContact CG2-CE2 3.77Å; I302-F306 HydrophobicContact CG2-CZ 4.33Å; I302-F306 WeakPolarHBondContact O-CG 3.5Å; I302-F306 PolarHBondContact O-N 3.4Å; I302-F306 VanDerWaalsContact O-N 3.09Å; I302-W316 HydrophobicContact CB-CH2 4.13Å; I302-W316 HydrophobicContact CB-CZ2 4.48Å; I302-W316 HydrophobicContact CG2-CE3 4.42Å; I302-W316 HydrophobicContact CG2-CH2 3.51Å; I302-W316 HydrophobicContact CG2-CZ2 3.74Å; I302-W316 HydrophobicContact CG2-CZ3 3.88Å; I302-L400 HydrophobicContact CD1-CD2 3.95Å; I302-L400 HydrophobicContact CG1-CD2 3.81Å; I302-F405 HydrophobicContact CB-CD1 4.48Å; I302-F405 HydrophobicContact CB-CE1 4.17Å; I302-F405 HydrophobicContact CG1-CD1 4.24Å; I302-F405 HydrophobicContact CG1-CD2 4.45Å; I302-F405 HydrophobicContact CG1-CE1 4.09Å; I302-F405 HydrophobicContact CG1-CE2 4.31Å; I302-F405 HydrophobicContact CG1-CG 4.4Å; I302-F405 HydrophobicContact CG1-CZ 4.12Å; I302-F405 HydrophobicContact CG2-CE1 3.81Å; I302-F405 HydrophobicContact CG2-CZ 4.02Å
303S98.1Very high96.7Very high9 Ų937.5 Ų37.56%0.06320%0.199CC..Hα-helixtrans-59.5-50.2-179.9-176.40000111.8I299 Q300 A305 F306 E307 V325 S326I299-S303 WeakPolarHBondContact O-CB 3.38Å; I299-S303 PolarHBondContact O-N 3.25Å; Q300-S303 PolarHBondContact O-N 3.49Å; S303-A305 VanDerWaalsContact C-N 3.35Å; S303-A305 PolarHBondContact O-N 2.65Å; S303-F306 WeakPolarHBondContact O-CB 3.39Å; S303-F306 PolarHBondContact O-N 2.87Å; S303-F306 VanDerWaalsContact O-N 3.13Å; S303-E307 PolarHBondContact O-N 3.02Å; S303-E307 VanDerWaalsContact O-N 3.12Å; S303-V325 WeakPolarHBondContact OG-CA 3.15Å; S303-S326 WeakPolarHBondContact OG-CB 3.48Å; S303-S326 PolarHBondContact OG-N 3.23Å
304A97.9Very high97.1Very high25 Ų2536.8 Ų36.821%0.20719%0.192CC..Hα-helixtrans-61.3-41.6179.900000112.1Q300 F306 E307 Q308 E402Q300-A304 WeakPolarHBondContact O-CB 3.29Å; Q300-A304 PolarHBondContact O-N 3.43Å; A304-F306 VanDerWaalsContact C-N 3.29Å; A304-F306 PolarHBondContact O-N 3.33Å; A304-E307 WeakPolarHBondContact O-CB 3.28Å; A304-E307 PolarHBondContact O-N 2.89Å; A304-E307 VanDerWaalsContact O-N 3.15Å; A304-Q308 PolarHBondContact O-N 3.46Å; A304-E402 VanDerWaalsContact CB-CD 3.4Å; A304-E402 HydrophobicContact CB-CG 3.88Å
305A98.2Very high97.4Very high0 Ų036.2 Ų36.20%019%0.187CC..Hα-helixtrans-63.9-32.6175.800000113.1A301 I302 S303 Q308 E402 F405A301-A305 WeakPolarHBondContact O-CB 3.17Å; A301-A305 PolarHBondContact O-N 3.14Å; A301-A305 VanDerWaalsContact O-N 3.15Å; I302-A305 PolarHBondContact O-N 3.42Å; S303-A305 VanDerWaalsContact C-N 3.35Å; S303-A305 PolarHBondContact O-N 2.65Å; A305-Q308 PolarHBondContact O-N 2.88Å; A305-E402 HydrophobicContact CB-CG 4.1Å; A305-F405 HydrophobicContact CB-CD1 3.65Å; A305-F405 HydrophobicContact CB-CE1 4.42Å
306F98.4Very high97.6Very high3 Ų335.6 Ų35.61%0.01318%0.183CC..Hα-helixtrans-72-30.6174-75.2-19.7000113.4F283 I302 S303 A304 Q308 L309 I314 W316 L331 I352 F405 I409F283-F306 HydrophobicContact CB-CZ 4.4Å; F283-F306 AromaticContact CD1-CE2 3.82Å; F283-F306 HydrophobicContact CD1-CE2 3.82Å; F283-F306 AromaticContact CD1-CZ 3.6Å; F283-F306 HydrophobicContact CD1-CZ 3.6Å; F283-F306 HydrophobicContact CE1-CZ 4.38Å; F283-F306 HydrophobicContact CG-CZ 4.49Å; I302-F306 HydrophobicContact CG2-CD2 4.01Å; I302-F306 HydrophobicContact CG2-CE2 3.77Å; I302-F306 HydrophobicContact CG2-CZ 4.33Å; I302-F306 WeakPolarHBondContact O-CG 3.5Å; I302-F306 PolarHBondContact O-N 3.4Å; I302-F306 VanDerWaalsContact O-N 3.09Å; S303-F306 WeakPolarHBondContact O-CB 3.39Å; S303-F306 PolarHBondContact O-N 2.87Å; S303-F306 VanDerWaalsContact O-N 3.13Å; A304-F306 VanDerWaalsContact C-N 3.29Å; A304-F306 PolarHBondContact O-N 3.33Å; F306-Q308 PolarHBondContact O-N 3.39Å; F306-L309 HydrophobicContact CD1-CD1 4.42Å; F306-L309 PolarHBondContact O-N 2.97Å; F306-L309 VanDerWaalsContact O-N 3.08Å; F306-I314 HydrophobicContact CB-CD1 3.76Å; F306-I314 HydrophobicContact CD1-CD1 3.56Å; F306-I314 HydrophobicContact CD1-CG2 4.26Å; F306-I314 HydrophobicContact CD2-CD1 4.43Å; F306-I314 HydrophobicContact CD2-CG2 3.95Å; F306-I314 HydrophobicContact CE1-CD1 4.11Å; F306-I314 HydrophobicContact CE1-CG2 3.96Å; F306-I314 HydrophobicContact CE2-CG2 3.65Å; F306-I314 HydrophobicContact CG-CD1 3.7Å; F306-I314 HydrophobicContact CG-CG2 4.22Å; F306-I314 HydrophobicContact CZ-CG2 3.61Å; F306-W316 HydrophobicContact CD2-CE3 4.09Å; F306-W316 HydrophobicContact CD2-CZ3 4.4Å; F306-W316 HydrophobicContact CE2-CD2 4.13Å; F306-W316 AromaticContact CE2-CE3 3.95Å; F306-W316 HydrophobicContact CE2-CE3 3.95Å; F306-W316 HydrophobicContact CE2-CG 4.41Å; F306-L331 HydrophobicContact CD2-CD1 3.84Å; F306-L331 HydrophobicContact CE2-CD1 4.29Å; F306-I352 HydrophobicContact CE1-CD1 3.85Å; F306-I352 HydrophobicContact CZ-CD1 3.88Å; F306-F405 AromaticContact CD1-CE1 3.98Å; F306-F405 HydrophobicContact CD1-CE1 3.98Å; F306-F405 AromaticContact CE1-CE1 3.59Å; F306-F405 HydrophobicContact CE1-CE1 3.59Å; F306-F405 AromaticContact CE1-CZ 3.96Å; F306-F405 HydrophobicContact CE1-CZ 3.96Å; F306-F405 AromaticContact CZ-CE1 3.96Å; F306-F405 HydrophobicContact CZ-CE1 3.96Å; F306-F405 AromaticContact CZ-CZ 4Å; F306-F405 HydrophobicContact CZ-CZ 4Å; F306-I409 HydrophobicContact CD1-CD1 4.04Å; F306-I409 HydrophobicContact CE1-CD1 3.7Å
307E97.3Very high97.7Very high91 Ų9133.6 Ų33.643%0.42517%0.17SC..Hα-helixtrans-63.3-26.7172.6-64.6-173.1168.900112.6S303 A304 L309 S326 K328S303-E307 PolarHBondContact O-N 3.02Å; S303-E307 VanDerWaalsContact O-N 3.12Å; A304-E307 WeakPolarHBondContact O-CB 3.28Å; A304-E307 PolarHBondContact O-N 2.89Å; A304-E307 VanDerWaalsContact O-N 3.15Å; E307-L309 PolarHBondContact O-N 3.47Å; E307-S326 WeakPolarHBondContact CG-OG 3.45Å; E307-S326 WeakPolarHBondContact OE1-CB 3.33Å; E307-S326 PolarHBondContact OE1-OG 3.32Å; E307-K328 HydrophobicContact CG-CG 4.25Å
308Q97.6Very high97.8Very high80 Ų8027.6 Ų27.637%0.37414%0.142SC..THydrogen-bonded Turntrans-78.53.2175.4-59.4-173.150.600114.1A304 A305 F306 P310 E402 Y406A304-Q308 PolarHBondContact O-N 3.46Å; A305-Q308 PolarHBondContact O-N 2.88Å; F306-Q308 PolarHBondContact O-N 3.39Å; Q308-P310 WeakPolarHBondContact O-CD 3.42Å; Q308-E402 PolarHBondContact NE2-OE1 2.58Å; Q308-Y406 HydrophobicContact CB-CD2 3.85Å; Q308-Y406 HydrophobicContact CB-CE2 3.5Å; Q308-Y406 VanDerWaalsContact CB-CE2 3.5Å
309L97.9Very high97.7Very high0 Ų029.6 Ų29.60%015%0.153CC..  trans-122.647.3-178.7-64169.9000112.9I281 F306 E307 Q311 Y312 I314 N330 Y406 I409 L410I281-L309 HydrophobicContact CD1-CD1 4.1Å; F306-L309 HydrophobicContact CD1-CD1 4.42Å; F306-L309 PolarHBondContact O-N 2.97Å; F306-L309 VanDerWaalsContact O-N 3.08Å; E307-L309 PolarHBondContact O-N 3.47Å; L309-Q311 VanDerWaalsContact C-OE1 3.27Å; L309-Q311 PolarHBondContact O-N 2.84Å; L309-Y312 HydrophobicContact CB-CD2 4.26Å; L309-Y312 HydrophobicContact CD2-CD2 4.11Å; L309-Y312 HydrophobicContact CD2-CE2 4.34Å; L309-Y312 PolarHBondContact O-N 3.25Å; L309-I314 HydrophobicContact CB-CD1 4.24Å; L309-N330 PolarHBondContact O-ND2 2.9Å; L309-Y406 HydrophobicContact CD2-CD2 4.33Å; L309-Y406 HydrophobicContact CD2-CE2 3.69Å; L309-Y406 HydrophobicContact CG-CD2 4.24Å; L309-Y406 HydrophobicContact CG-CE2 3.93Å; L309-I409 HydrophobicContact CD1-CB 4.47Å; L309-I409 HydrophobicContact CD1-CD1 3.85Å; L309-I409 HydrophobicContact CD1-CG2 3.76Å; L309-L410 HydrophobicContact CD2-CD2 4.05Å
310P97.1Very high97.5Very high90 Ų9030.1 Ų30.158%0.58416%0.159SC*.THydrogen-bonded Turntrans-61.3-21.4-176.928.3-37.3000113.6Q308 Y312Q308-P310 WeakPolarHBondContact O-CD 3.42Å; P310-Y312 VanDerWaalsContact C-N 3.25Å; P310-Y312 PolarHBondContact O-N 3.47Å
311Q97.9Very high97.4Very high59 Ų5929.1 Ų29.128%0.27616%0.157SC..THydrogen-bonded Turntrans-76.1-517772.8-80.214.300114.4K278 L309K278-Q311 WeakPolarHBondContact CB-O 3.12Å; K278-Q311 HydrophobicContact CD-CB 4.17Å; K278-Q311 HydrophobicContact CD-CG 3.8Å; K278-Q311 HydrophobicContact CG-CB 4.24Å; K278-Q311 HydrophobicContact CG-CG 4.28Å; K278-Q311 PolarHBondContact N-O 2.87Å; L309-Q311 VanDerWaalsContact C-OE1 3.27Å; L309-Q311 PolarHBondContact O-N 2.84Å
312Y98.5Very high97.2Very high26 Ų2632.6 Ų32.610%0.10218%0.177CC..SBendtrans-118.5148177.1-68.2-79.2000110.9K278 G279 I281 L309 P310 N330 V349 L413K278-Y312 HydrophobicContact CB-CD1 3.98Å; K278-Y312 HydrophobicContact CB-CE1 3.56Å; G279-Y312 WeakPolarHBondContact O-CA 3.09Å; G279-Y312 WeakPolarHBondContact O-CD1 3.44Å; I281-Y312 HydrophobicContact CD1-CD2 4.38Å; I281-Y312 HydrophobicContact CD1-CG 4.06Å; I281-Y312 HydrophobicContact CG1-CD1 4.47Å; I281-Y312 HydrophobicContact CG1-CG 4.4Å; L309-Y312 HydrophobicContact CB-CD2 4.26Å; L309-Y312 HydrophobicContact CD2-CD2 4.11Å; L309-Y312 HydrophobicContact CD2-CE2 4.34Å; L309-Y312 PolarHBondContact O-N 3.25Å; P310-Y312 VanDerWaalsContact C-N 3.25Å; P310-Y312 PolarHBondContact O-N 3.47Å; Y312-N330 WeakPolarHBondContact O-CB 3.48Å; Y312-N330 PolarHBondContact O-ND2 2.6Å; Y312-N330 VanDerWaalsContact O-ND2 3.16Å; Y312-V349 HydrophobicContact CD1-CG2 4.18Å; Y312-V349 HydrophobicContact CE1-CG2 4.09Å; Y312-L413 HydrophobicContact CD2-CD1 4.41Å; Y312-L413 HydrophobicContact CE1-CD1 4.25Å; Y312-L413 HydrophobicContact CE1-CD2 4.49Å; Y312-L413 HydrophobicContact CE2-CD1 3.81Å
313R98.6Very high96.9Very high39 Ų3937.2 Ų37.215%0.14721%0.209CC..EExtended strand (participates in β ladder)trans-86.6132.6168.1-69.2-73.8171.3-170.1-7.9108.3F271 D274 S277 G279 T280 I281 P329F271-R313 HydrophobicContact CD1-CB 4.28Å; F271-R313 HydrophobicContact CE1-CB 3.78Å; F271-R313 HydrophobicContact CE1-CG 4.44Å; F271-R313 HydrophobicContact CZ-CB 4.22Å; F271-R313 WeakPolarHBondContact O-CD 3.43Å; F271-R313 VanDerWaalsContact O-CG 3.26Å; F271-R313 WeakPolarHBondContact O-CG 3.23Å; D274-R313 HydrophobicContact CB-CG 4.41Å; D274-R313 IonicContact OD2-CZ 2.63Å; D274-R313 IonicContact OD2-NE 2.77Å; D274-R313 IonicContact OD2-NH2 3.76Å; D274-R313 PolarHBondContact OD2-NH2 2.84Å; S277-R313 WeakPolarHBondContact OG-CG 3.42Å; S277-R313 PolarHBondContact OG-N 3.21Å; G279-R313 PolarHBondContact O-N 2.93Å; T280-R313 CarbonylContact C-O 3.57Å; T280-R313 WeakPolarHBondContact CA-O 3.43Å; I281-R313 PolarHBondContact N-O 3.44Å; R313-P329 PolarHBondContact NH1-O 3.11Å
314I98.7Very high96.7Very high0 Ų040.2 Ų40.20%022%0.223CC..EExtended strand (participates in β ladder)trans-124.8119.9-173.9-52.8179.3000108.5I281 F306 L309 N330 L331 K332I281-I314 HydrophobicContact CB-CG1 4.27Å; I281-I314 HydrophobicContact CB-CG2 4.49Å; I281-I314 HydrophobicContact CD1-CG1 4.44Å; I281-I314 CarbonylContact O-C 3.49Å; I281-I314 WeakPolarHBondContact O-CA 3.39Å; F306-I314 HydrophobicContact CB-CD1 3.76Å; F306-I314 HydrophobicContact CD1-CD1 3.56Å; F306-I314 HydrophobicContact CD1-CG2 4.26Å; F306-I314 HydrophobicContact CD2-CD1 4.43Å; F306-I314 HydrophobicContact CD2-CG2 3.95Å; F306-I314 HydrophobicContact CE1-CD1 4.11Å; F306-I314 HydrophobicContact CE1-CG2 3.96Å; F306-I314 HydrophobicContact CE2-CG2 3.65Å; F306-I314 HydrophobicContact CG-CD1 3.7Å; F306-I314 HydrophobicContact CG-CG2 4.22Å; F306-I314 HydrophobicContact CZ-CG2 3.61Å; L309-I314 HydrophobicContact CB-CD1 4.24Å; I314-N330 PolarHBondContact N-O 2.91Å; I314-L331 HydrophobicContact CB-CD1 3.54Å; I314-L331 HydrophobicContact CG2-CD1 3.41Å; I314-L331 VanDerWaalsContact CG2-CD1 3.41Å; I314-L331 CarbonylContact O-C 3.59Å; I314-L331 WeakPolarHBondContact O-CA 3.43Å; I314-K332 PolarHBondContact O-N 3.44Å
315V98.5Very high96.6Very high0 Ų039.7 Ų39.70%022%0.218CC..EExtended strand (participates in β ladder)trans-107.5113.8174.9-178.60000108.3Y268 F271 T280 I281 V282 F283 K332 I337 L342Y268-V315 HydrophobicContact CE1-CG1 3.97Å; F271-V315 HydrophobicContact CD1-CG2 3.92Å; F271-V315 HydrophobicContact CE1-CG2 3.65Å; T280-V315 HydrophobicContact CG2-CG2 4.14Å; I281-V315 PolarHBondContact O-N 2.96Å; V282-V315 CarbonylContact C-O 3.48Å; V282-V315 WeakPolarHBondContact CA-O 3.35Å; F283-V315 PolarHBondContact N-O 2.79Å; V315-K332 CarbonylContact C-O 3.34Å; V315-K332 WeakPolarHBondContact CA-O 3.42Å; V315-I337 HydrophobicContact CG1-CB 4.25Å; V315-I337 HydrophobicContact CG1-CD1 4.2Å; V315-I337 HydrophobicContact CG1-CG2 3.81Å; V315-L342 HydrophobicContact CB-CD1 4.34Å; V315-L342 HydrophobicContact CG1-CD1 3.74Å; V315-L342 HydrophobicContact CG2-CD2 4.22Å
316W98.1Very high96.3Very high0 Ų040.4 Ų40.40%022%0.223CC..EExtended strand (participates in β ladder)trans-116.1115.5-175.5-174.58.3000111.4F283 W291 I299 I302 F306 F318 V325 L331 K332 I333 D334F283-W316 HydrophobicContact CB-CB 4.32Å; F283-W316 HydrophobicContact CB-CG 4.17Å; F283-W316 AromaticContact CD1-CD1 3.78Å; F283-W316 HydrophobicContact CD1-CD2 4.38Å; F283-W316 HydrophobicContact CD1-CG 4.19Å; F283-W316 AromaticContact CD1-NE1 3.76Å; F283-W316 AromaticContact CD2-CD1 3.99Å; F283-W316 AromaticContact CE1-NE1 3.99Å; F283-W316 AromaticContact CG-CD1 3.58Å; F283-W316 HydrophobicContact CG-CG 4.25Å; F283-W316 AromaticContact CG-NE1 3.88Å; W291-W316 AromaticContact CE2-NE1 3.67Å; W291-W316 HydrophobicContact CE3-CZ2 4.29Å; W291-W316 AromaticContact CH2-CZ2 3.74Å; W291-W316 HydrophobicContact CH2-CZ2 3.74Å; W291-W316 AromaticContact CH2-NE1 3.75Å; W291-W316 AromaticContact CZ2-CE2 3.96Å; W291-W316 HydrophobicContact CZ2-CZ2 4.06Å; W291-W316 AromaticContact CZ2-NE1 3.23Å; W291-W316 AromaticContact CZ3-CZ2 3.86Å; W291-W316 HydrophobicContact CZ3-CZ2 3.86Å; I299-W316 HydrophobicContact CG2-CH2 4.29Å; I302-W316 HydrophobicContact CB-CH2 4.13Å; I302-W316 HydrophobicContact CB-CZ2 4.48Å; I302-W316 HydrophobicContact CG2-CE3 4.42Å; I302-W316 HydrophobicContact CG2-CH2 3.51Å; I302-W316 HydrophobicContact CG2-CZ2 3.74Å; I302-W316 HydrophobicContact CG2-CZ3 3.88Å; F306-W316 HydrophobicContact CD2-CE3 4.09Å; F306-W316 HydrophobicContact CD2-CZ3 4.4Å; F306-W316 HydrophobicContact CE2-CD2 4.13Å; F306-W316 AromaticContact CE2-CE3 3.95Å; F306-W316 HydrophobicContact CE2-CE3 3.95Å; F306-W316 HydrophobicContact CE2-CG 4.41Å; W316-F318 HydrophobicContact CD2-CB 4.17Å; W316-F318 AromaticContact CE2-CD2 3.79Å; W316-F318 HydrophobicContact CG-CB 4.19Å; W316-F318 HydrophobicContact CH2-CD2 4.15Å; W316-F318 HydrophobicContact CH2-CE2 4.31Å; W316-F318 AromaticContact CZ2-CD2 3.55Å; W316-F318 HydrophobicContact CZ2-CD2 3.55Å; W316-F318 HydrophobicContact CZ2-CE2 4.01Å; W316-F318 HydrophobicContact CZ2-CG 4.31Å; W316-F318 PolarHBondContact O-N 3.31Å; W316-V325 HydrophobicContact CE3-CG1 4.44Å; W316-V325 HydrophobicContact CH2-CG1 3.57Å; W316-V325 HydrophobicContact CZ3-CB 4.02Å; W316-V325 HydrophobicContact CZ3-CG1 3.44Å; W316-V325 VanDerWaalsContact CZ3-CG1 3.44Å; W316-L331 HydrophobicContact CB-CD1 4.39Å; W316-L331 HydrophobicContact CE3-CD2 4.48Å; W316-K332 PolarHBondContact N-O 3.32Å; W316-I333 HydrophobicContact CE3-CD1 4.37Å; W316-I333 WeakPolarHBondContact O-CA 3.34Å; W316-D334 PolarHBondContact O-N 3.36Å
317Q97.5Very high95.9Very high16 Ų1644.2 Ų44.28%0.07526%0.262CS..EExtended strand (participates in β ladder)trans-72106.1167.6-169.7-169.2-26.700110F283 S284 G286 W291 D334 P335 W336 I337F283-Q317 WeakPolarHBondContact O-CB 3.45Å; F283-Q317 PolarHBondContact O-N 3.37Å; S284-Q317 PolarHBondContact OG-OE1 3.49Å; G286-Q317 PolarHBondContact O-NE2 2.94Å; W291-Q317 PolarHBondContact NE1-O 2.8Å; Q317-D334 CarbonylContact C-O 3.56Å; Q317-D334 VanDerWaalsContact CA-O 3.28Å; Q317-D334 WeakPolarHBondContact CA-O 3.29Å; Q317-P335 VanDerWaalsContact CG-O 3.22Å; Q317-P335 WeakPolarHBondContact CG-O 3.4Å; Q317-W336 VanDerWaalsContact NE2-CZ3 3.32Å; Q317-I337 HydrophobicContact CB-CD1 4Å; Q317-I337 HydrophobicContact CB-CG1 4.02Å; Q317-I337 HydrophobicContact CB-CG2 4.11Å; Q317-I337 HydrophobicContact CG-CG1 4.47Å
318F97Very high95.8Very high3 Ų345 Ų451%0.01326%0.264CS..  trans-145.2118.4-174-179.3-98.9000110.8W291 I299 W316 G320 V325 I333 D334 P335W291-F318 HydrophobicContact CB-CD2 3.72Å; W291-F318 HydrophobicContact CB-CE2 3.62Å; W291-F318 HydrophobicContact CB-CZ 4.41Å; W291-F318 AromaticContact CD1-CD2 3.86Å; W291-F318 AromaticContact CD2-CD2 3.46Å; W291-F318 HydrophobicContact CD2-CD2 3.46Å; W291-F318 VanDerWaalsContact CD2-CD2 3.46Å; W291-F318 AromaticContact CD2-CE2 3.8Å; W291-F318 HydrophobicContact CD2-CE2 3.8Å; W291-F318 AromaticContact CE2-CD2 3.94Å; W291-F318 AromaticContact CE3-CD2 3.87Å; W291-F318 HydrophobicContact CE3-CD2 3.87Å; W291-F318 AromaticContact CE3-CE2 3.8Å; W291-F318 HydrophobicContact CE3-CE2 3.8Å; W291-F318 AromaticContact CG-CD2 3.4Å; W291-F318 HydrophobicContact CG-CD2 3.4Å; W291-F318 AromaticContact CG-CE2 3.75Å; W291-F318 HydrophobicContact CG-CE2 3.75Å; W291-F318 HydrophobicContact CG-CG 4.3Å; I299-F318 HydrophobicContact CD1-CE2 4.11Å; I299-F318 HydrophobicContact CD1-CZ 4.24Å; I299-F318 HydrophobicContact CG1-CE2 4.24Å; I299-F318 HydrophobicContact CG2-CE2 4Å; I299-F318 HydrophobicContact CG2-CZ 4Å; W316-F318 HydrophobicContact CD2-CB 4.17Å; W316-F318 AromaticContact CE2-CD2 3.79Å; W316-F318 HydrophobicContact CG-CB 4.19Å; W316-F318 HydrophobicContact CH2-CD2 4.15Å; W316-F318 HydrophobicContact CH2-CE2 4.31Å; W316-F318 AromaticContact CZ2-CD2 3.55Å; W316-F318 HydrophobicContact CZ2-CD2 3.55Å; W316-F318 HydrophobicContact CZ2-CE2 4.01Å; W316-F318 HydrophobicContact CZ2-CG 4.31Å; W316-F318 PolarHBondContact O-N 3.31Å; F318-G320 WeakPolarHBondContact CE1-O 3.28Å; F318-V325 HydrophobicContact CE1-CG1 4.17Å; F318-V325 HydrophobicContact CE1-CG2 4.27Å; F318-V325 HydrophobicContact CE2-CG1 4.4Å; F318-V325 HydrophobicContact CZ-CG1 4.02Å; F318-I333 HydrophobicContact CB-CG2 3.66Å; F318-I333 HydrophobicContact CD1-CG2 3.91Å; F318-I333 HydrophobicContact CG-CG2 4.18Å; F318-D334 PolarHBondContact N-O 3.19Å; F318-D334 CarbonylContact O-C 3.59Å; F318-P335 WeakPolarHBondContact O-CA 3.49Å
319N94.4Very high95.7Very high58 Ų5846.3 Ų46.331%0.3128%0.279SS..  trans-107.113.6179.273.2-41.1000112.7D290 W291 P335D290-N319 PolarHBondContact OD1-ND2 2.82Å; W291-N319 WeakPolarHBondContact CB-OD1 3.49Å; W291-N319 VanDerWaalsContact CD1-OD1 3.27Å; W291-N319 PolarHBondContact N-OD1 3.17Å; N319-P335 HydrophobicContact CB-CB 4.21Å
320G93.8Very high95.7Very high14 Ų1446.9 Ų46.914%0.14428%0.282CS..SBendtrans-86.2-167.2177.200000112.5F318 V322F318-G320 WeakPolarHBondContact CE1-O 3.28Å; G320-V322 PolarHBondContact O-N 3.46Å
321N94.3Very high95.7Very high83 Ų8343.5 Ų43.544%0.44426%0.259SS..  trans-73109.6177.1-176.71.1000111.2S323 M324N321-S323 VanDerWaalsContact CG-OG 3.27Å; N321-S323 PolarHBondContact ND2-OG 3.46Å; N321-S323 PolarHBondContact O-N 3.26Å; N321-S323 VanDerWaalsContact O-N 3.16Å; N321-S323 WeakPolarHBondContact OD1-CB 3.44Å; N321-S323 PolarHBondContact OD1-N 2.95Å; N321-S323 PolarHBondContact OD1-OG 3.21Å; N321-M324 HydrophobicContact CB-CE 4.07Å; N321-M324 HydrophobicContact CB-CG 4.12Å; N321-M324 HydrophobicContact CB-SD 4.08Å; N321-M324 WeakPolarHBondContact O-CB 3.42Å; N321-M324 PolarHBondContact O-N 2.86Å
322V93.6Very high95.7Very high87 Ų8741.6 Ų41.653%0.52725%0.25SS..G310 helixtrans-62.3-21.3-178.6-176.70000112.4G320 M324 V325G320-V322 PolarHBondContact O-N 3.46Å; V322-M324 PolarHBondContact O-N 3.1Å; V322-V325 HydrophobicContact CG1-CG2 4.13Å; V322-V325 WeakPolarHBondContact O-CG2 3.5Å; V322-V325 PolarHBondContact O-N 3.39Å
323S92.7Very high95.6Very high99 Ų9942 Ų4269%0.69225%0.254SS*.G310 helixtrans-68.7-12.1175.680.30000113.8N321N321-S323 VanDerWaalsContact CG-OG 3.27Å; N321-S323 PolarHBondContact ND2-OG 3.46Å; N321-S323 PolarHBondContact O-N 3.26Å; N321-S323 VanDerWaalsContact O-N 3.16Å; N321-S323 WeakPolarHBondContact OD1-CB 3.44Å; N321-S323 PolarHBondContact OD1-N 2.95Å; N321-S323 PolarHBondContact OD1-OG 3.21Å
324M92.8Very high95.5Very high71 Ų7141.8 Ų41.835%0.3526%0.256SS..G310 helixtrans-89.7-6.5179.1-61.1-179.6176.500113.3V296 I299 N321 V322V296-M324 HydrophobicContact CG2-CE 4.33Å; V296-M324 HydrophobicContact CG2-SD 4.29Å; I299-M324 HydrophobicContact CD1-SD 4.47Å; I299-M324 HydrophobicContact CG2-CB 4.15Å; N321-M324 HydrophobicContact CB-CE 4.07Å; N321-M324 HydrophobicContact CB-CG 4.12Å; N321-M324 HydrophobicContact CB-SD 4.08Å; N321-M324 WeakPolarHBondContact O-CB 3.42Å; N321-M324 PolarHBondContact O-N 2.86Å; V322-M324 PolarHBondContact O-N 3.1Å
325V95.4Very high95.3Very high15 Ų1545.4 Ų45.49%0.09128%0.279CS..SBendtrans-121.3156.7-173.7-65.60000110.3I299 S303 W316 F318 V322 I333I299-V325 HydrophobicContact CG2-CG1 3.49Å; I299-V325 VanDerWaalsContact CG2-CG1 3.49Å; S303-V325 WeakPolarHBondContact OG-CA 3.15Å; W316-V325 HydrophobicContact CE3-CG1 4.44Å; W316-V325 HydrophobicContact CH2-CG1 3.57Å; W316-V325 HydrophobicContact CZ3-CB 4.02Å; W316-V325 HydrophobicContact CZ3-CG1 3.44Å; W316-V325 VanDerWaalsContact CZ3-CG1 3.44Å; F318-V325 HydrophobicContact CE1-CG1 4.17Å; F318-V325 HydrophobicContact CE1-CG2 4.27Å; F318-V325 HydrophobicContact CE2-CG1 4.4Å; F318-V325 HydrophobicContact CZ-CG1 4.02Å; V322-V325 HydrophobicContact CG1-CG2 4.13Å; V322-V325 WeakPolarHBondContact O-CG2 3.5Å; V322-V325 PolarHBondContact O-N 3.39Å; V325-I333 HydrophobicContact CB-CD1 3.9Å; V325-I333 HydrophobicContact CG2-CD1 3.32Å
326S92.1Very high95.1Very high15 Ų1551.9 Ų51.911%0.10530%0.304CS..  trans-63.6138.6-174.3-165.50000112.8S303 E307 K328S303-S326 WeakPolarHBondContact OG-CB 3.48Å; S303-S326 PolarHBondContact OG-N 3.23Å; E307-S326 WeakPolarHBondContact CG-OG 3.45Å; E307-S326 WeakPolarHBondContact OE1-CB 3.33Å; E307-S326 PolarHBondContact OE1-OG 3.32Å; S326-K328 VanDerWaalsContact C-N 3.31Å; S326-K328 WeakPolarHBondContact OG-CG 3.07Å; S326-K328 PolarHBondContact OG-N 2.85Å
327G90.9Very high95Very high82 Ų8252.7 Ų52.785%0.84531%0.308SS*.  trans-9017.8171.900000114.2
328K95.4Very high94.9Very high109 Ų10953.9 Ų53.947%0.47432%0.317SS..  trans-62.6142.3-177.5-69-76.1-178.8-175.90111E307 S326 N330 L331E307-K328 HydrophobicContact CG-CG 4.25Å; S326-K328 VanDerWaalsContact C-N 3.31Å; S326-K328 WeakPolarHBondContact OG-CG 3.07Å; S326-K328 PolarHBondContact OG-N 2.85Å; K328-N330 VanDerWaalsContact CB-OD1 3.31Å; K328-N330 WeakPolarHBondContact CB-OD1 3.38Å; K328-N330 PolarHBondContact O-N 3.31Å; K328-N330 VanDerWaalsContact O-N 3.07Å; K328-L331 PolarHBondContact O-N 2.68Å
329P95.3Very high94.8Very high106 Ų10654.7 Ų54.769%0.68832%0.321SS*.THydrogen-bonded Turntrans-66.6-16-173.327.1-36.2000114R313 L331R313-P329 PolarHBondContact NH1-O 3.11Å; P329-L331 VanDerWaalsContact C-N 3.3Å
330N96.8Very high94.8Very high12 Ų1253.9 Ų53.96%0.06432%0.319CS..THydrogen-bonded Turntrans-83.8-2.1175.673.4-63.1000113.6F271 L309 Y312 I314 K328F271-N330 VanDerWaalsContact CZ-O 3.26Å; F271-N330 WeakPolarHBondContact CZ-O 3.31Å; L309-N330 PolarHBondContact O-ND2 2.9Å; Y312-N330 WeakPolarHBondContact O-CB 3.48Å; Y312-N330 PolarHBondContact O-ND2 2.6Å; Y312-N330 VanDerWaalsContact O-ND2 3.16Å; I314-N330 PolarHBondContact N-O 2.91Å; K328-N330 VanDerWaalsContact CB-OD1 3.31Å; K328-N330 WeakPolarHBondContact CB-OD1 3.38Å; K328-N330 PolarHBondContact O-N 3.31Å; K328-N330 VanDerWaalsContact O-N 3.07Å
331L97.7Very high94.9Very high19 Ų1953.5 Ų53.510%0.09932%0.315CS..EExtended strand (participates in β ladder)trans-113121179.7-170.262.2000110F306 I314 W316 K328 P329 I333F306-L331 HydrophobicContact CD2-CD1 3.84Å; F306-L331 HydrophobicContact CE2-CD1 4.29Å; I314-L331 HydrophobicContact CB-CD1 3.54Å; I314-L331 HydrophobicContact CG2-CD1 3.41Å; I314-L331 VanDerWaalsContact CG2-CD1 3.41Å; I314-L331 CarbonylContact O-C 3.59Å; I314-L331 WeakPolarHBondContact O-CA 3.43Å; W316-L331 HydrophobicContact CB-CD1 4.39Å; W316-L331 HydrophobicContact CE3-CD2 4.48Å; K328-L331 PolarHBondContact O-N 2.68Å; P329-L331 VanDerWaalsContact C-N 3.3Å; L331-I333 HydrophobicContact CD1-CG1 4.49Å; L331-I333 HydrophobicContact CD2-CD1 3.67Å; L331-I333 HydrophobicContact CD2-CG1 4.1Å; L331-I333 HydrophobicContact CG-CD1 3.92Å; L331-I333 HydrophobicContact CG-CG1 3.75Å
332K97.3Very high95.1Very high19 Ų1949.6 Ų49.68%0.08329%0.294CS..EExtended strand (participates in β ladder)trans-109.3121.6172.3177.2161172.756.50108.8E267 Y268 F271 I314 V315 W316 D334E267-K332 VanDerWaalsContact CD-NZ 3.3Å; E267-K332 WeakPolarHBondContact OE1-CE 3.45Å; E267-K332 IonicContact OE1-NZ 2.89Å; E267-K332 PolarHBondContact OE1-NZ 2.89Å; E267-K332 IonicContact OE2-NZ 3.13Å; Y268-K332 HydrophobicContact CD1-CD 3.97Å; Y268-K332 HydrophobicContact CE1-CD 3.83Å; Y268-K332 HydrophobicContact CE1-CG 4.43Å; F271-K332 HydrophobicContact CB-CD 4.49Å; F271-K332 HydrophobicContact CD1-CB 4.1Å; F271-K332 HydrophobicContact CD1-CD 4.38Å; F271-K332 HydrophobicContact CD2-CB 4.14Å; F271-K332 HydrophobicContact CE1-CB 3.69Å; F271-K332 HydrophobicContact CE2-CB 3.73Å; F271-K332 HydrophobicContact CG-CB 4.3Å; F271-K332 HydrophobicContact CG-CD 4.22Å; F271-K332 HydrophobicContact CZ-CB 3.47Å; F271-K332 VanDerWaalsContact CZ-CB 3.47Å; I314-K332 PolarHBondContact O-N 3.44Å; V315-K332 CarbonylContact C-O 3.34Å; V315-K332 WeakPolarHBondContact CA-O 3.42Å; W316-K332 PolarHBondContact N-O 3.32Å; K332-D334 WeakPolarHBondContact CE-OD2 3.24Å; K332-D334 IonicContact NZ-OD1 2.6Å; K332-D334 PolarHBondContact NZ-OD1 3.33Å; K332-D334 IonicContact NZ-OD2 3.58Å; K332-D334 PolarHBondContact NZ-OD2 3.49Å
333I97.5Very high95.3Very high35 Ų3545.5 Ų45.518%0.17927%0.269CS..EExtended strand (participates in β ladder)trans-121.8116.9-172.2-51.3-174.4000108.3W316 F318 V325 L331W316-I333 HydrophobicContact CE3-CD1 4.37Å; W316-I333 WeakPolarHBondContact O-CA 3.34Å; F318-I333 HydrophobicContact CB-CG2 3.66Å; F318-I333 HydrophobicContact CD1-CG2 3.91Å; F318-I333 HydrophobicContact CG-CG2 4.18Å; V325-I333 HydrophobicContact CB-CD1 3.9Å; V325-I333 HydrophobicContact CG2-CD1 3.32Å; L331-I333 HydrophobicContact CD1-CG1 4.49Å; L331-I333 HydrophobicContact CD2-CD1 3.67Å; L331-I333 HydrophobicContact CD2-CG1 4.1Å; L331-I333 HydrophobicContact CG-CD1 3.92Å; L331-I333 HydrophobicContact CG-CG1 3.75Å
334D96.4Very high95.4Very high35 Ų3543.5 Ų43.519%0.18725%0.249CC..EExtended strand (participates in β ladder)trans-135.5149.1178.1-59.3-55.5000109.7Y268 W316 Q317 F318 K332 W336 I337Y268-D334 VanDerWaalsContact CZ-OD2 3.29Å; Y268-D334 PolarHBondContact OH-OD2 2.71Å; W316-D334 PolarHBondContact O-N 3.36Å; Q317-D334 CarbonylContact C-O 3.56Å; Q317-D334 VanDerWaalsContact CA-O 3.28Å; Q317-D334 WeakPolarHBondContact CA-O 3.29Å; F318-D334 PolarHBondContact N-O 3.19Å; F318-D334 CarbonylContact O-C 3.59Å; K332-D334 WeakPolarHBondContact CE-OD2 3.24Å; K332-D334 IonicContact NZ-OD1 2.6Å; K332-D334 PolarHBondContact NZ-OD1 3.33Å; K332-D334 IonicContact NZ-OD2 3.58Å; K332-D334 PolarHBondContact NZ-OD2 3.49Å; D334-W336 PolarHBondContact O-N 3.17Å; D334-I337 HydrophobicContact CB-CG2 4.13Å
335P94.5Very high95.6Very high75 Ų7541.8 Ų41.849%0.48724%0.24SC..SBendtrans-63.5-29.7176.524.9-34000112.7Q317 F318 N319Q317-P335 VanDerWaalsContact CG-O 3.22Å; Q317-P335 WeakPolarHBondContact CG-O 3.4Å; F318-P335 WeakPolarHBondContact O-CA 3.49Å; N319-P335 HydrophobicContact CB-CB 4.21Å
336W93.5Very high95.6Very high137 Ų13746.5 Ų46.552%0.51927%0.273SS..SBendtrans-140.3135.1177.5-78.9107.1000110.3H287 Q317 D334H287-W336 HydrophobicContact CB-CH2 3.95Å; H287-W336 AromaticContact CD2-CH2 3.55Å; H287-W336 AromaticContact CE1-CH2 3.89Å; H287-W336 AromaticContact CE1-CZ3 3.94Å; H287-W336 AromaticContact CG-CH2 3.47Å; H287-W336 VanDerWaalsContact CG-CH2 3.47Å; H287-W336 AromaticContact ND1-CH2 3.7Å; H287-W336 AromaticContact ND1-CZ3 4Å; H287-W336 AromaticContact NE2-CH2 3.88Å; Q317-W336 VanDerWaalsContact NE2-CZ3 3.32Å; D334-W336 PolarHBondContact O-N 3.17Å
337I95.7Very high95.9Very high16 Ų1649.5 Ų49.58%0.08228%0.282CS..  trans-121.2151.9-176.867.3173.8000110.7V282 V315 Q317 D334 L339 L342V282-I337 HydrophobicContact CG1-CD1 3.71Å; V315-I337 HydrophobicContact CG1-CB 4.25Å; V315-I337 HydrophobicContact CG1-CD1 4.2Å; V315-I337 HydrophobicContact CG1-CG2 3.81Å; Q317-I337 HydrophobicContact CB-CD1 4Å; Q317-I337 HydrophobicContact CB-CG1 4.02Å; Q317-I337 HydrophobicContact CB-CG2 4.11Å; Q317-I337 HydrophobicContact CG-CG1 4.47Å; D334-I337 HydrophobicContact CB-CG2 4.13Å; I337-L339 HydrophobicContact CD1-CD1 4.35Å; I337-L339 HydrophobicContact CG1-CB 4.27Å; I337-L339 PolarHBondContact O-N 2.95Å; I337-L342 HydrophobicContact CB-CD1 3.99Å; I337-L342 HydrophobicContact CD1-CD1 3.92Å; I337-L342 HydrophobicContact CG1-CD1 4.2Å
338P95.5Very high96.3Very high42 Ų4245.8 Ų45.827%0.27324%0.244SC..  trans-76.765.6175.432.9-35.8000110.7L264 Y268 A341 L342L264-P338 HydrophobicContact CD2-CG 4.07Å; Y268-P338 HydrophobicContact CD1-CG 4.4Å; Y268-P338 HydrophobicContact CD2-CG 3.62Å; Y268-P338 HydrophobicContact CE1-CG 4.35Å; Y268-P338 HydrophobicContact CE2-CG 3.58Å; Y268-P338 HydrophobicContact CG-CG 4.06Å; P338-A341 HydrophobicContact CB-CB 4.37Å; P338-A341 PolarHBondContact O-N 2.8Å; P338-A341 VanDerWaalsContact O-N 3.08Å; P338-L342 HydrophobicContact CG-CD1 4.21Å; P338-L342 HydrophobicContact CG-CG 4.24Å; P338-L342 PolarHBondContact O-N 2.7Å
339L95.1Very high96.4Very high20 Ų2042.9 Ų42.911%0.10524%0.235CC..Hα-helixtrans-51.3-48.5-169.5177.567.5000113.7V282 I337 A341 L342 L343 F351V282-L339 HydrophobicContact CG1-CD1 3.69Å; I337-L339 HydrophobicContact CD1-CD1 4.35Å; I337-L339 HydrophobicContact CG1-CB 4.27Å; I337-L339 PolarHBondContact O-N 2.95Å; L339-A341 VanDerWaalsContact C-N 3.32Å; L339-A341 PolarHBondContact O-N 3.5Å; L339-L342 PolarHBondContact O-N 2.88Å; L339-L343 HydrophobicContact CD1-CD1 3.88Å; L339-L343 HydrophobicContact CD1-CD2 4.23Å; L339-L343 HydrophobicContact CD1-CG 3.8Å; L339-L343 HydrophobicContact CG-CD1 3.99Å; L339-L343 HydrophobicContact CG-CG 4.27Å; L339-L343 WeakPolarHBondContact O-CG 3.48Å; L339-L343 PolarHBondContact O-N 3.38Å; L339-F351 HydrophobicContact CD1-CD2 4.3Å; L339-F351 HydrophobicContact CD1-CE2 3.57Å; L339-F351 HydrophobicContact CD1-CZ 3.86Å; L339-F351 HydrophobicContact CD2-CE2 4.49Å; L339-F351 HydrophobicContact CD2-CZ 4.02Å
340P94.6Very high96.6Very high41 Ų4137.8 Ų37.827%0.26620%0.202SC..Hα-helixtrans-61.1-37.8179.9-25.836.4000113.8P259 Q344P259-P340 HydrophobicContact CB-CB 3.79Å; P259-P340 HydrophobicContact CB-CG 4.41Å; P259-P340 HydrophobicContact CG-CB 4.04Å; P259-P340 HydrophobicContact CG-CG 4.33Å; P340-Q344 WeakPolarHBondContact O-CB 3.46Å; P340-Q344 WeakPolarHBondContact O-CG 3.44Å; P340-Q344 PolarHBondContact O-N 2.94Å; P340-Q344 VanDerWaalsContact O-N 3.14Å; P340-Q344 PolarHBondContact O-NE2 3.48Å
341A96.6Very high96.7Very high6 Ų637.2 Ų37.25%0.0520%0.199CC..Hα-helixtrans-71.1-39.7178.300000111.1A262 L264 P338 L339 Q344 H345A262-A341 HydrophobicContact CB-CB 4Å; A262-A341 WeakPolarHBondContact O-CB 3.4Å; L264-A341 HydrophobicContact CD2-CB 3.57Å; L264-A341 HydrophobicContact CG-CB 4.16Å; P338-A341 HydrophobicContact CB-CB 4.37Å; P338-A341 PolarHBondContact O-N 2.8Å; P338-A341 VanDerWaalsContact O-N 3.08Å; L339-A341 VanDerWaalsContact C-N 3.32Å; L339-A341 PolarHBondContact O-N 3.5Å; A341-Q344 PolarHBondContact O-N 3.44Å; A341-H345 PolarHBondContact O-N 2.89Å; A341-H345 VanDerWaalsContact O-N 3.16Å
342L97.8Very high96.7Very high0 Ų036.3 Ų36.30%019%0.194CC..Hα-helixtrans-63.6-45.4175.9-71.4166.2000111.7L264 Y268 V272 V282 V315 I337 P338 L339 Q344 H345 T348L264-L342 HydrophobicContact CD1-CD2 4.38Å; L264-L342 HydrophobicContact CD2-CD2 3.79Å; L264-L342 HydrophobicContact CD2-CG 3.91Å; Y268-L342 HydrophobicContact CD1-CD2 4.2Å; V272-L342 HydrophobicContact CG2-CD2 3.88Å; V282-L342 HydrophobicContact CG1-CD1 4.4Å; V282-L342 HydrophobicContact CG2-CB 3.95Å; V315-L342 HydrophobicContact CB-CD1 4.34Å; V315-L342 HydrophobicContact CG1-CD1 3.74Å; V315-L342 HydrophobicContact CG2-CD2 4.22Å; I337-L342 HydrophobicContact CB-CD1 3.99Å; I337-L342 HydrophobicContact CD1-CD1 3.92Å; I337-L342 HydrophobicContact CG1-CD1 4.2Å; P338-L342 HydrophobicContact CG-CD1 4.21Å; P338-L342 HydrophobicContact CG-CG 4.24Å; P338-L342 PolarHBondContact O-N 2.7Å; L339-L342 PolarHBondContact O-N 2.88Å; L342-Q344 VanDerWaalsContact C-N 3.32Å; L342-Q344 PolarHBondContact O-N 2.79Å; L342-H345 WeakPolarHBondContact O-CB 3.1Å; L342-H345 PolarHBondContact O-N 3.5Å; L342-T348 WeakPolarHBondContact O-CB 3.31Å; L342-T348 PolarHBondContact O-OG1 2.87Å
343L97.6Very high96.8Very high2 Ų235.4 Ų35.41%0.0119%0.19CC..Hα-helixtrans-67.2-32.4178.6-66.6-179.3000112.8L339 H345 T348 F351 E362 F366 V368L339-L343 HydrophobicContact CD1-CD1 3.88Å; L339-L343 HydrophobicContact CD1-CD2 4.23Å; L339-L343 HydrophobicContact CD1-CG 3.8Å; L339-L343 HydrophobicContact CG-CD1 3.99Å; L339-L343 HydrophobicContact CG-CG 4.27Å; L339-L343 WeakPolarHBondContact O-CG 3.48Å; L339-L343 PolarHBondContact O-N 3.38Å; L343-H345 VanDerWaalsContact C-N 3.28Å; L343-H345 PolarHBondContact O-N 3.19Å; L343-T348 HydrophobicContact CD2-CG2 4.32Å; L343-F351 HydrophobicContact CD1-CD1 4.38Å; L343-F351 HydrophobicContact CD1-CE1 4.28Å; L343-F351 HydrophobicContact CD2-CB 3.86Å; L343-F351 HydrophobicContact CD2-CD1 4.18Å; L343-F351 HydrophobicContact CD2-CD2 3.91Å; L343-F351 HydrophobicContact CD2-CE2 4.5Å; L343-F351 HydrophobicContact CD2-CG 3.73Å; L343-E362 HydrophobicContact CD1-CB 3.85Å; L343-F366 HydrophobicContact CB-CB 4.35Å; L343-F366 HydrophobicContact CB-CD2 3.65Å; L343-F366 HydrophobicContact CB-CE2 4.46Å; L343-F366 HydrophobicContact CB-CG 4.38Å; L343-F366 VanDerWaalsContact O-CB 3.27Å; L343-F366 WeakPolarHBondContact O-CB 3.44Å; L343-V368 HydrophobicContact CB-CG2 4.5Å; L343-V368 HydrophobicContact CD2-CB 4.38Å; L343-V368 HydrophobicContact CD2-CG1 4.34Å; L343-V368 HydrophobicContact CD2-CG2 4.27Å; L343-V368 WeakPolarHBondContact O-CG2 3.33Å
344Q95.8Very high96.6Very high57 Ų5734.6 Ų34.627%0.26619%0.185SC..Hα-helixtrans-69.6-25.5175.2-80.6176.675.400113.5K260 P340 A341 L342 S346 F366K260-Q344 PolarHBondContact O-NE2 3.45Å; P340-Q344 WeakPolarHBondContact O-CB 3.46Å; P340-Q344 WeakPolarHBondContact O-CG 3.44Å; P340-Q344 PolarHBondContact O-N 2.94Å; P340-Q344 VanDerWaalsContact O-N 3.14Å; P340-Q344 PolarHBondContact O-NE2 3.48Å; A341-Q344 PolarHBondContact O-N 3.44Å; L342-Q344 VanDerWaalsContact C-N 3.32Å; L342-Q344 PolarHBondContact O-N 2.79Å; Q344-S346 PolarHBondContact O-N 3.31Å; Q344-F366 HydrophobicContact CB-CD1 4.38Å; Q344-F366 VanDerWaalsContact CD-CE1 3.5Å; Q344-F366 VanDerWaalsContact CD-CZ 3.45Å; Q344-F366 HydrophobicContact CG-CD1 3.29Å; Q344-F366 HydrophobicContact CG-CD2 3.81Å; Q344-F366 HydrophobicContact CG-CE1 3.12Å; Q344-F366 HydrophobicContact CG-CE2 3.64Å; Q344-F366 HydrophobicContact CG-CG 3.64Å; Q344-F366 HydrophobicContact CG-CZ 3.29Å
345H97Very high96.5Very high35 Ų3532.9 Ų32.916%0.16218%0.176CC..SBendtrans-67.4132.6-174.9-161.1-85.7000111.6L264 V272 E273 A341 L342 L343 R347 T348L264-H345 HydrophobicContact CD1-CB 4.33Å; V272-H345 HydrophobicContact CG1-CB 4.49Å; V272-H345 VanDerWaalsContact CG1-ND1 3.26Å; V272-H345 WeakPolarHBondContact CG1-ND1 3.31Å; E273-H345 IonicContact OE1-NE2 3.68Å; E273-H345 PolarHBondContact OE1-NE2 2.98Å; A341-H345 PolarHBondContact O-N 2.89Å; A341-H345 VanDerWaalsContact O-N 3.16Å; L342-H345 WeakPolarHBondContact O-CB 3.1Å; L342-H345 PolarHBondContact O-N 3.5Å; L343-H345 VanDerWaalsContact C-N 3.28Å; L343-H345 PolarHBondContact O-N 3.19Å; H345-R347 WeakPolarHBondContact ND1-CB 3.27Å; H345-R347 PolarHBondContact ND1-N 3.37Å; H345-R347 PolarHBondContact O-N 2.93Å; H345-R347 VanDerWaalsContact O-N 3.1Å; H345-T348 WeakPolarHBondContact O-CB 3.43Å; H345-T348 PolarHBondContact O-N 3.35Å
346S95.6Very high96.4Very high114 Ų11429.8 Ų29.880%0.79716%0.158SC*.THydrogen-bonded Turntrans-60.8-25.2-175.160.70000114.1Q344 T348Q344-S346 PolarHBondContact O-N 3.31Å; S346-T348 VanDerWaalsContact C-N 3.3Å; S346-T348 PolarHBondContact O-N 2.83Å
347R97.3Very high96.1Very high77 Ų7724.4 Ų24.429%0.29114%0.139SC..THydrogen-bonded Turntrans-73.7-14.6175.5-65.1-66.9-148.6145.113.9113.7V272 E273 D274 S277 G279 T280 H345 V349V272-R347 HydrophobicContact CG1-CB 3.83Å; V272-R347 HydrophobicContact CG1-CG 4.34Å; E273-R347 PolarHBondContact O-NH2 3.38Å; D274-R347 PolarHBondContact O-NH2 2.79Å; S277-R347 PolarHBondContact O-NH1 3.2Å; S277-R347 VanDerWaalsContact O-NH1 3.12Å; G279-R347 CarbonylContact C-O 3.58Å; G279-R347 VanDerWaalsContact CA-O 3.26Å; G279-R347 WeakPolarHBondContact CA-O 3.49Å; T280-R347 PolarHBondContact N-O 3.29Å; H345-R347 WeakPolarHBondContact ND1-CB 3.27Å; H345-R347 PolarHBondContact ND1-N 3.37Å; H345-R347 PolarHBondContact O-N 2.93Å; H345-R347 VanDerWaalsContact O-N 3.1Å; R347-V349 PolarHBondContact O-N 3.21Å
348T98.4Very high95.8Very high5 Ų525.3 Ų25.33%0.03114%0.142CC..EExtended strand (participates in β ladder)trans-76.2117.8-177.1-63.70000111.3T280 V282 L342 L343 H345 S346 V368T280-T348 WeakPolarHBondContact O-CA 3.34Å; V282-T348 HydrophobicContact CG2-CG2 3.83Å; L342-T348 WeakPolarHBondContact O-CB 3.31Å; L342-T348 PolarHBondContact O-OG1 2.87Å; L343-T348 HydrophobicContact CD2-CG2 4.32Å; H345-T348 WeakPolarHBondContact O-CB 3.43Å; H345-T348 PolarHBondContact O-N 3.35Å; S346-T348 VanDerWaalsContact C-N 3.3Å; S346-T348 PolarHBondContact O-N 2.83Å; T348-V368 HydrophobicContact CG2-CG1 3.83Å; T348-V368 HydrophobicContact CG2-CG2 4.13Å
349V98.4Very high95.7Very high47 Ų4723.8 Ų23.829%0.28513%0.133SC..EExtended strand (participates in β ladder)trans-109.1-23-172.2-67.60000113.6T280 I281 Y312 R347 L413T280-V349 WeakPolarHBondContact O-CG2 3.49Å; T280-V349 PolarHBondContact O-N 3.16Å; I281-V349 HydrophobicContact CG1-CG2 4.47Å; Y312-V349 HydrophobicContact CD1-CG2 4.18Å; Y312-V349 HydrophobicContact CE1-CG2 4.09Å; R347-V349 PolarHBondContact O-N 3.21Å; V349-L413 HydrophobicContact CB-CD2 4.11Å; V349-L413 HydrophobicContact CG2-CD2 3.7Å
350L98.8Very high95.6Very high0 Ų022.9 Ų22.90%013%0.128CC..EExtended strand (participates in β ladder)trans-148.8137.9-178.2176.163.7000110.9I281 V282 I352 L371 I409 V412 L413I281-L350 WeakPolarHBondContact CA-O 3.45Å; I281-L350 HydrophobicContact CD1-CD2 4.48Å; I281-L350 HydrophobicContact CG1-CB 4.25Å; I281-L350 HydrophobicContact CG1-CD2 4.49Å; I281-L350 HydrophobicContact CG2-CB 4.26Å; I281-L350 HydrophobicContact CG2-CD2 4.02Å; I281-L350 HydrophobicContact CG2-CG 4.21Å; V282-L350 PolarHBondContact N-O 2.79Å; L350-I352 HydrophobicContact CD2-CD1 4.48Å; L350-I352 HydrophobicContact CD2-CG1 4.16Å; L350-I352 HydrophobicContact CG-CG1 4.22Å; L350-L371 HydrophobicContact CD1-CB 4.2Å; L350-I409 HydrophobicContact CD2-CB 4.19Å; L350-I409 HydrophobicContact CD2-CG1 4.11Å; L350-I409 HydrophobicContact CD2-CG2 3.75Å; L350-V412 HydrophobicContact CD1-CB 3.92Å; L350-V412 HydrophobicContact CD1-CG1 3.64Å; L350-V412 HydrophobicContact CD1-CG2 4.38Å; L350-L413 HydrophobicContact CB-CD2 3.88Å; L350-L413 HydrophobicContact CD2-CD2 4.42Å; L350-L413 HydrophobicContact CD2-CG 4.33Å
351F98.8Very high95.6Very high0 Ų021.4 Ų21.40%012%0.117CC..EExtended strand (participates in β ladder)trans-115.6112.3170.4-178.7-141.2000111.5V282 L339 L343 T353 A363 V368 P369 M370 L371V282-F351 HydrophobicContact CB-CD2 4.12Å; V282-F351 HydrophobicContact CG1-CD2 4.1Å; V282-F351 HydrophobicContact CG1-CE2 4.24Å; V282-F351 CarbonylContact O-C 3.58Å; V282-F351 WeakPolarHBondContact O-CA 3.36Å; V282-F351 WeakPolarHBondContact O-CD2 3.23Å; L339-F351 HydrophobicContact CD1-CD2 4.3Å; L339-F351 HydrophobicContact CD1-CE2 3.57Å; L339-F351 HydrophobicContact CD1-CZ 3.86Å; L339-F351 HydrophobicContact CD2-CE2 4.49Å; L339-F351 HydrophobicContact CD2-CZ 4.02Å; L343-F351 HydrophobicContact CD1-CD1 4.38Å; L343-F351 HydrophobicContact CD1-CE1 4.28Å; L343-F351 HydrophobicContact CD2-CB 3.86Å; L343-F351 HydrophobicContact CD2-CD1 4.18Å; L343-F351 HydrophobicContact CD2-CD2 3.91Å; L343-F351 HydrophobicContact CD2-CE2 4.5Å; L343-F351 HydrophobicContact CD2-CG 3.73Å; F351-T353 HydrophobicContact CD1-CG2 3.77Å; F351-T353 HydrophobicContact CE1-CG2 3.7Å; F351-T353 WeakPolarHBondContact CE1-OG1 2.99Å; F351-T353 HydrophobicContact CG-CG2 4.46Å; F351-T353 VanDerWaalsContact CZ-CB 3.44Å; F351-T353 HydrophobicContact CZ-CG2 4.31Å; F351-T353 WeakPolarHBondContact CZ-OG1 3.28Å; F351-A363 HydrophobicContact CD1-CB 3.73Å; F351-A363 HydrophobicContact CE1-CB 4.32Å; F351-V368 HydrophobicContact CB-CB 4.48Å; F351-V368 HydrophobicContact CB-CG1 3.74Å; F351-P369 PolarHBondContact N-O 2.86Å; F351-M370 HydrophobicContact CB-CG 4.4Å; F351-M370 HydrophobicContact CD1-CG 4.18Å; F351-M370 CarbonylContact O-C 3.55Å; F351-M370 VanDerWaalsContact O-CA 3.22Å; F351-M370 WeakPolarHBondContact O-CA 3.32Å; F351-L371 PolarHBondContact O-N 3.16Å
352I98.8Very high95.5Very high0 Ų021.7 Ų21.70%012%0.117CC..EExtended strand (participates in β ladder)trans-87.7118172.5-49.8-177.3000107.8I281 V282 F283 S284 F306 L350 L371 I373 F405 I409I281-I352 HydrophobicContact CG2-CD1 3.74Å; I281-I352 HydrophobicContact CG2-CG1 3.94Å; V282-I352 PolarHBondContact O-N 2.94Å; F283-I352 WeakPolarHBondContact CA-O 3.41Å; F283-I352 HydrophobicContact CB-CB 4.1Å; F283-I352 HydrophobicContact CD1-CB 4.3Å; F283-I352 HydrophobicContact CD1-CD1 4.28Å; F283-I352 HydrophobicContact CD1-CG2 4.04Å; F283-I352 HydrophobicContact CD2-CB 4.19Å; F283-I352 HydrophobicContact CD2-CG2 3.98Å; F283-I352 HydrophobicContact CE1-CG2 4.02Å; F283-I352 HydrophobicContact CE2-CG2 4.04Å; F283-I352 HydrophobicContact CG-CB 3.93Å; F283-I352 HydrophobicContact CG-CG2 3.96Å; F283-I352 HydrophobicContact CZ-CG2 4Å; S284-I352 PolarHBondContact N-O 3.28Å; F306-I352 HydrophobicContact CE1-CD1 3.85Å; F306-I352 HydrophobicContact CZ-CD1 3.88Å; L350-I352 HydrophobicContact CD2-CD1 4.48Å; L350-I352 HydrophobicContact CD2-CG1 4.16Å; L350-I352 HydrophobicContact CG-CG1 4.22Å; I352-L371 WeakPolarHBondContact CA-O 3.41Å; I352-L371 HydrophobicContact CB-CB 4.44Å; I352-L371 HydrophobicContact CD1-CD2 4.15Å; I352-L371 HydrophobicContact CG1-CB 4.09Å; I352-L371 HydrophobicContact CG1-CD2 4.15Å; I352-L371 HydrophobicContact CG2-CB 4.36Å; I352-L371 HydrophobicContact CG2-CD2 4.19Å; I352-L371 HydrophobicContact CG2-CG 4.32Å; I352-I373 HydrophobicContact CG2-CD1 4.19Å; I352-F405 HydrophobicContact CD1-CE1 4.41Å; I352-F405 HydrophobicContact CD1-CE2 4.14Å; I352-F405 HydrophobicContact CD1-CZ 3.59Å; I352-F405 HydrophobicContact CG2-CE2 4Å; I352-F405 HydrophobicContact CG2-CZ 4.25Å; I352-I409 HydrophobicContact CD1-CD1 4Å; I352-I409 HydrophobicContact CD1-CG1 4.01Å
353T98.1Very high95.4Very high0 Ų021.7 Ų21.70%012%0.117CC..EExtended strand (participates in β ladder)trans-147.6151.3-169.3-170.30000113.3S284 F351 S355 S359 M370 L371 S372 I373S284-T353 WeakPolarHBondContact O-CA 3.4Å; S284-T353 PolarHBondContact O-OG1 3.4Å; F351-T353 HydrophobicContact CD1-CG2 3.77Å; F351-T353 HydrophobicContact CE1-CG2 3.7Å; F351-T353 WeakPolarHBondContact CE1-OG1 2.99Å; F351-T353 HydrophobicContact CG-CG2 4.46Å; F351-T353 VanDerWaalsContact CZ-CB 3.44Å; F351-T353 HydrophobicContact CZ-CG2 4.31Å; F351-T353 WeakPolarHBondContact CZ-OG1 3.28Å; T353-S355 PolarHBondContact O-N 3.48Å; T353-S355 PolarHBondContact OG1-N 2.84Å; T353-S359 PolarHBondContact OG1-OG 3.04Å; T353-M370 HydrophobicContact CG2-CB 4.45Å; T353-M370 HydrophobicContact CG2-CG 4.15Å; T353-M370 HydrophobicContact CG2-SD 4.06Å; T353-L371 PolarHBondContact N-O 2.83Å; T353-S372 CarbonylContact O-C 3.58Å; T353-S372 VanDerWaalsContact O-CA 3.25Å; T353-S372 WeakPolarHBondContact O-CA 3.45Å; T353-I373 PolarHBondContact O-N 3.22Å
354H95.1Very high95.4Very high17 Ų1721.6 Ų21.68%0.07912%0.117CC..  trans-70-6166.871.1-44000113.3F285 G356 I373 L375 Q379F285-H354 HydrophobicContact CB-CB 4.22Å; F285-H354 HydrophobicContact CD1-CB 3.73Å; F285-H354 HydrophobicContact CE1-CB 4.27Å; F285-H354 HydrophobicContact CG-CB 4.05Å; F285-H354 PolarHBondContact O-CD2 3.03Å; F285-H354 PolarHBondContact O-CE1 3.34Å; F285-H354 PolarHBondContact O-ND1 3.31Å; F285-H354 PolarHBondContact O-NE2 3.01Å; H354-G356 VanDerWaalsContact C-N 3.35Å; H354-G356 PolarHBondContact CE1-N 3.46Å; H354-G356 PolarHBondContact ND1-N 3.13Å; H354-G356 WeakPolarHBondContact NE2-CA 3.4Å; H354-G356 PolarHBondContact O-N 3.22Å; H354-I373 VanDerWaalsContact CA-O 3.32Å; H354-I373 WeakPolarHBondContact CA-O 3.4Å; H354-L375 HydrophobicContact CB-CG 4.23Å; H354-Q379 PolarHBondContact CD2-NE2 3.01Å; H354-Q379 WeakPolarHBondContact O-CB 3.29Å; H354-Q379 WeakPolarHBondContact O-CG 3.45Å
355S93.8Very high95.4Very high0 Ų019.5 Ų19.50%011%0.108CC..  trans60.638.6-175-70.20000113.7T353 S372 N382T353-S355 PolarHBondContact O-N 3.48Å; T353-S355 PolarHBondContact OG1-N 2.84Å; S355-S372 WeakPolarHBondContact OG-CB 3.48Å; S355-S372 PolarHBondContact OG-OG 3.45Å; S355-N382 WeakPolarHBondContact O-CB 3.41Å; S355-N382 PolarHBondContact O-ND2 3.14Å
356G91.3Very high95.4Very high9 Ų919.8 Ų19.89%0.09311%0.109CC..  trans-55.7145.8162.400000110.6H354 K358 S359 F360H354-G356 VanDerWaalsContact C-N 3.35Å; H354-G356 PolarHBondContact CE1-N 3.46Å; H354-G356 PolarHBondContact ND1-N 3.13Å; H354-G356 WeakPolarHBondContact NE2-CA 3.4Å; H354-G356 PolarHBondContact O-N 3.22Å; G356-K358 VanDerWaalsContact C-N 3.26Å; G356-K358 PolarHBondContact O-N 3.38Å; G356-K358 VanDerWaalsContact O-N 3.09Å; G356-S359 PolarHBondContact O-N 3.43Å; G356-S359 PolarHBondContact O-OG 2.62Å; G356-F360 VanDerWaalsContact O-CB 3.27Å; G356-F360 WeakPolarHBondContact O-CB 3.45Å; G356-F360 PolarHBondContact O-N 3.43Å
357I88.6Confident95.5Very high25 Ų2514.9 Ų14.913%0.1288%0.075CC..Hα-helixtrans-51.1-41.7-169.1-167.9162.9000114.1S236 M237 R361 N382S236-I357 VanDerWaalsContact OG-CD1 3.25Å; S236-I357 WeakPolarHBondContact OG-CD1 3.33Å; M237-I357 HydrophobicContact CB-CD1 4.35Å; M237-I357 HydrophobicContact CE-CD1 3.88Å; M237-I357 HydrophobicContact CE-CG1 3.69Å; I357-R361 PolarHBondContact O-N 3.44Å; I357-R361 VanDerWaalsContact O-N 3.1Å; I357-N382 PolarHBondContact N-ND2 3.27Å
358K88.9Confident95.5Very high34 Ų3411.3 Ų11.315%0.1486%0.062CC..Hα-helixtrans-73.7-50.1179.9-65.5-169-65.7-169.50112.8S37 Y256 G356 F360 R361 E362S37-K358 PolarHBondContact O-NZ 3.38Å; Y256-K358 HydrophobicContact CD1-CB 4.48Å; Y256-K358 HydrophobicContact CD1-CG 4.5Å; Y256-K358 HydrophobicContact CD2-CD 3.97Å; Y256-K358 HydrophobicContact CD2-CG 4.14Å; Y256-K358 HydrophobicContact CE1-CB 4.32Å; Y256-K358 HydrophobicContact CE2-CD 3.72Å; Y256-K358 HydrophobicContact CE2-CG 4.24Å; Y256-K358 HydrophobicContact CG-CG 4.26Å; G356-K358 VanDerWaalsContact C-N 3.26Å; G356-K358 PolarHBondContact O-N 3.38Å; G356-K358 VanDerWaalsContact O-N 3.09Å; K358-F360 PolarHBondContact O-N 3.24Å; K358-R361 CarbonylContact O-C 3.57Å; K358-R361 WeakPolarHBondContact O-CA 3.2Å; K358-R361 WeakPolarHBondContact O-CB 3.37Å; K358-R361 PolarHBondContact O-N 3.4Å; K358-E362 WeakPolarHBondContact O-CG 3.12Å; K358-E362 PolarHBondContact O-N 2.74Å
359S92.4Very high95.5Very high11 Ų1111.3 Ų11.38%0.0776%0.062CC..Hα-helixtrans-65.2-33.2-179.661.70000111.5T353 G356 E362 A363T353-S359 PolarHBondContact OG1-OG 3.04Å; G356-S359 PolarHBondContact O-N 3.43Å; G356-S359 PolarHBondContact O-OG 2.62Å; S359-E362 PolarHBondContact O-N 2.88Å; S359-A363 WeakPolarHBondContact O-CB 3.34Å; S359-A363 PolarHBondContact O-N 2.88Å
360F94.7Very high95.6Very high0 Ų09.1 Ų9.10%05%0.049CC..Hα-helixtrans-60.1-47.4168.7175.8-115.5000111.3M237 L241 G356 K358 A363 V364 M370 N382 L385 T386 L391M237-F360 HydrophobicContact CE-CD1 4.3Å; M237-F360 HydrophobicContact CE-CE1 4.41Å; L241-F360 HydrophobicContact CD1-CE1 3.57Å; L241-F360 HydrophobicContact CD1-CZ 3.67Å; L241-F360 HydrophobicContact CD2-CD1 3.99Å; L241-F360 HydrophobicContact CD2-CE1 3.65Å; L241-F360 HydrophobicContact CG-CD1 4.41Å; L241-F360 HydrophobicContact CG-CE1 3.58Å; L241-F360 HydrophobicContact CG-CZ 4.2Å; G356-F360 VanDerWaalsContact O-CB 3.27Å; G356-F360 WeakPolarHBondContact O-CB 3.45Å; G356-F360 PolarHBondContact O-N 3.43Å; K358-F360 PolarHBondContact O-N 3.24Å; F360-A363 PolarHBondContact O-N 2.89Å; F360-V364 WeakPolarHBondContact O-CG2 3.22Å; F360-V364 PolarHBondContact O-N 3.33Å; F360-M370 HydrophobicContact CD2-CE 3.59Å; F360-M370 HydrophobicContact CD2-SD 3.7Å; F360-M370 HydrophobicContact CE2-CE 3.58Å; F360-M370 HydrophobicContact CE2-SD 4.29Å; F360-N382 HydrophobicContact CD1-CB 4.45Å; F360-N382 HydrophobicContact CG-CB 4.44Å; F360-L385 HydrophobicContact CE1-CB 4.15Å; F360-L385 HydrophobicContact CE1-CD1 4.02Å; F360-L385 HydrophobicContact CE2-CB 4.48Å; F360-L385 HydrophobicContact CZ-CB 3.67Å; F360-L385 HydrophobicContact CZ-CD1 4.39Å; F360-T386 WeakPolarHBondContact CE2-OG1 3.49Å; F360-L391 HydrophobicContact CE2-CD1 4.23Å; F360-L391 HydrophobicContact CZ-CD1 4.4Å
361R93Very high95.5Very high10 Ų109.1 Ų9.14%0.0385%0.049CC..Hα-helixtrans-63-41.9176.5-175.158.4176.6113.4-3.7112.8D255 Y256 I357 K358 V364 C365D255-R361 IonicContact OD1-NE 3.44Å; D255-R361 PolarHBondContact OD1-NE 3.21Å; D255-R361 IonicContact OD2-CZ 2.9Å; D255-R361 IonicContact OD2-NE 2.82Å; D255-R361 PolarHBondContact OD2-NE 2.99Å; D255-R361 IonicContact OD2-NH2 3.96Å; D255-R361 PolarHBondContact OD2-NH2 2.79Å; Y256-R361 HydrophobicContact CD1-CB 4.22Å; Y256-R361 HydrophobicContact CD1-CG 4.07Å; I357-R361 PolarHBondContact O-N 3.44Å; I357-R361 VanDerWaalsContact O-N 3.1Å; K358-R361 CarbonylContact O-C 3.57Å; K358-R361 WeakPolarHBondContact O-CA 3.2Å; K358-R361 WeakPolarHBondContact O-CB 3.37Å; K358-R361 PolarHBondContact O-N 3.4Å; R361-V364 PolarHBondContact O-N 3.27Å; R361-C365 PolarHBondContact NH1-SG 3.02Å; R361-C365 VanDerWaalsContact NH1-SG 3.45Å; R361-C365 PolarHBondContact O-N 3.49Å; R361-C365 PolarHBondContact O-SG 2.76Å
362E94.5Very high95.5Very high13 Ų139.1 Ų9.16%0.0615%0.049CC..Hα-helixtrans-63-41.6177.7-69.9172.7-174.700111.9Y256 P259 L343 K358 S359 V364 C365 F366Y256-E362 HydrophobicContact CE1-CG 3.75Å; Y256-E362 WeakPolarHBondContact CE1-OE1 3.21Å; Y256-E362 PolarHBondContact OH-OE1 3.06Å; P259-E362 HydrophobicContact CG-CG 3.79Å; L343-E362 HydrophobicContact CD1-CB 3.85Å; K358-E362 WeakPolarHBondContact O-CG 3.12Å; K358-E362 PolarHBondContact O-N 2.74Å; S359-E362 PolarHBondContact O-N 2.88Å; E362-V364 VanDerWaalsContact C-N 3.27Å; E362-V364 PolarHBondContact O-N 2.94Å; E362-C365 WeakPolarHBondContact O-CB 3.31Å; E362-C365 PolarHBondContact O-N 3.42Å; E362-F366 HydrophobicContact CB-CD2 4.49Å; E362-F366 HydrophobicContact CB-CE2 4.31Å; E362-F366 WeakPolarHBondContact O-CD2 3.47Å; E362-F366 PolarHBondContact O-N 2.87Å
363A97.4Very high95.3Very high0 Ų09.2 Ų9.20%05%0.049CC..Hα-helixtrans-58.7-41.5173.800000111.7F351 S359 F360 A367 V368 M370 I422F351-A363 HydrophobicContact CD1-CB 3.73Å; F351-A363 HydrophobicContact CE1-CB 4.32Å; S359-A363 WeakPolarHBondContact O-CB 3.34Å; S359-A363 PolarHBondContact O-N 2.88Å; F360-A363 PolarHBondContact O-N 2.89Å; A363-A367 CarbonylContact O-C 3.57Å; A363-A367 WeakPolarHBondContact O-CA 3.33Å; A363-A367 PolarHBondContact O-N 2.84Å; A363-V368 PolarHBondContact O-N 3.32Å; A363-M370 HydrophobicContact CB-CE 4.06Å; A363-M370 HydrophobicContact CB-CG 3.8Å; A363-M370 HydrophobicContact CB-SD 3.46Å; A363-M370 WeakPolarHBondContact CB-SD 3.23Å; A363-I422 WeakPolarHBondContact O-CD1 3.43Å
364V96.6Very high95.1Very high0 Ų010.1 Ų10.10%06%0.055CC..Hα-helixtrans-69.4-44.3175.4-178.90000111.4L241 F360 R361 E362 F366 A367 M370 L391 I422 L425 S426 L429L241-V364 HydrophobicContact CD1-CG2 4Å; F360-V364 WeakPolarHBondContact O-CG2 3.22Å; F360-V364 PolarHBondContact O-N 3.33Å; R361-V364 PolarHBondContact O-N 3.27Å; E362-V364 VanDerWaalsContact C-N 3.27Å; E362-V364 PolarHBondContact O-N 2.94Å; V364-F366 VanDerWaalsContact C-N 3.29Å; V364-F366 PolarHBondContact O-N 3.19Å; V364-A367 PolarHBondContact O-N 3.28Å; V364-A367 VanDerWaalsContact O-N 3.1Å; V364-M370 HydrophobicContact CG2-CE 4.39Å; V364-L391 HydrophobicContact CG2-CD1 3.9Å; V364-I422 HydrophobicContact CG2-CD1 4.26Å; V364-I422 HydrophobicContact CG2-CG1 4.33Å; V364-L425 HydrophobicContact CG1-CD2 4.13Å; V364-L425 HydrophobicContact CG1-CG 3.99Å; V364-S426 WeakPolarHBondContact O-CB 3.39Å; V364-S426 PolarHBondContact O-OG 3.08Å; V364-S426 VanDerWaalsContact O-OG 3.14Å; V364-L429 HydrophobicContact CG1-CD1 3.54Å
365C95.1Very high94.8Very high12 Ų129.4 Ų9.48%0.0815%0.052CC..Hα-helixtrans-50.5-50.6175.6-74.70000111.6C258 R361 E362 A367 S426C258-C365 WeakPolarHBondContact CA-SG 3.25Å; C258-C365 HydrophobicContact CB-CB 3.69Å; C258-C365 WeakPolarHBondContact CB-SG 3.26Å; C258-C365 WeakPolarHBondContact SG-CB 3.15Å; C258-C365 CovalentContact SG-SG 2.03Å; C258-C365 PolarHBondContact SG-SG 2.87Å; R361-C365 PolarHBondContact NH1-SG 3.02Å; R361-C365 VanDerWaalsContact NH1-SG 3.45Å; R361-C365 PolarHBondContact O-N 3.49Å; R361-C365 PolarHBondContact O-SG 2.76Å; E362-C365 WeakPolarHBondContact O-CB 3.31Å; E362-C365 PolarHBondContact O-N 3.42Å; C365-A367 VanDerWaalsContact C-N 3.3Å; C365-A367 PolarHBondContact O-N 3.05Å; C365-S426 PolarHBondContact O-OG 3.16Å
366F97Very high94.4Very high42 Ų4211.1 Ų11.118%0.1846%0.06CC..THydrogen-bonded Turntrans-9412.3-175.9-49.1-52.9000113.3P259 L343 Q344 E362 V364 V368P259-F366 HydrophobicContact CB-CZ 4.11Å; P259-F366 HydrophobicContact CG-CE2 4.27Å; P259-F366 HydrophobicContact CG-CZ 4.23Å; P259-F366 WeakPolarHBondContact O-CZ 3.3Å; L343-F366 HydrophobicContact CB-CB 4.35Å; L343-F366 HydrophobicContact CB-CD2 3.65Å; L343-F366 HydrophobicContact CB-CE2 4.46Å; L343-F366 HydrophobicContact CB-CG 4.38Å; L343-F366 VanDerWaalsContact O-CB 3.27Å; L343-F366 WeakPolarHBondContact O-CB 3.44Å; Q344-F366 HydrophobicContact CB-CD1 4.38Å; Q344-F366 VanDerWaalsContact CD-CE1 3.5Å; Q344-F366 VanDerWaalsContact CD-CZ 3.45Å; Q344-F366 HydrophobicContact CG-CD1 3.29Å; Q344-F366 HydrophobicContact CG-CD2 3.81Å; Q344-F366 HydrophobicContact CG-CE1 3.12Å; Q344-F366 HydrophobicContact CG-CE2 3.64Å; Q344-F366 HydrophobicContact CG-CG 3.64Å; Q344-F366 HydrophobicContact CG-CZ 3.29Å; E362-F366 HydrophobicContact CB-CD2 4.49Å; E362-F366 HydrophobicContact CB-CE2 4.31Å; E362-F366 WeakPolarHBondContact O-CD2 3.47Å; E362-F366 PolarHBondContact O-N 2.87Å; V364-F366 VanDerWaalsContact C-N 3.29Å; V364-F366 PolarHBondContact O-N 3.19Å; F366-V368 VanDerWaalsContact C-N 3.27Å; F366-V368 HydrophobicContact CB-CG2 4.27Å; F366-V368 PolarHBondContact O-N 2.56Å
367A97.8Very high93.8Very high11 Ų1111 Ų119%0.0916%0.059CC..THydrogen-bonded Turntrans5240.4176.800000113.8A363 V364 C365 P369 K419 I422A363-A367 CarbonylContact O-C 3.57Å; A363-A367 WeakPolarHBondContact O-CA 3.33Å; A363-A367 PolarHBondContact O-N 2.84Å; V364-A367 PolarHBondContact O-N 3.28Å; V364-A367 VanDerWaalsContact O-N 3.1Å; C365-A367 VanDerWaalsContact C-N 3.3Å; C365-A367 PolarHBondContact O-N 3.05Å; A367-P369 WeakPolarHBondContact O-CD 3.37Å; A367-K419 VanDerWaalsContact O-CD 3.25Å; A367-K419 WeakPolarHBondContact O-CD 3.39Å; A367-K419 WeakPolarHBondContact O-CE 3.3Å; A367-K419 PolarHBondContact O-NZ 3.34Å; A367-I422 HydrophobicContact CB-CG2 4.14Å; A367-I422 WeakPolarHBondContact O-CG2 3.35Å
368V98.5Very high93.5Very high1 Ų111.5 Ų11.51%0.0066%0.061CC..  trans-97114.6178.6-175.20000110.2L343 T348 F351 A363 F366 I422L343-V368 HydrophobicContact CB-CG2 4.5Å; L343-V368 HydrophobicContact CD2-CB 4.38Å; L343-V368 HydrophobicContact CD2-CG1 4.34Å; L343-V368 HydrophobicContact CD2-CG2 4.27Å; L343-V368 WeakPolarHBondContact O-CG2 3.33Å; T348-V368 HydrophobicContact CG2-CG1 3.83Å; T348-V368 HydrophobicContact CG2-CG2 4.13Å; F351-V368 HydrophobicContact CB-CB 4.48Å; F351-V368 HydrophobicContact CB-CG1 3.74Å; A363-V368 PolarHBondContact O-N 3.32Å; F366-V368 VanDerWaalsContact C-N 3.27Å; F366-V368 HydrophobicContact CB-CG2 4.27Å; F366-V368 PolarHBondContact O-N 2.56Å; V368-I422 WeakPolarHBondContact O-CD1 3.25Å
369P98.8Very high93.6Very high6 Ų610.2 Ų10.24%0.0396%0.056CC..  trans-55.3152.5175.2-27.237000113F351 A367 L391 V412 K419 I422F351-P369 PolarHBondContact N-O 2.86Å; A367-P369 WeakPolarHBondContact O-CD 3.37Å; P369-L391 WeakPolarHBondContact CA-O 3.43Å; P369-V412 HydrophobicContact CB-CG1 3.47Å; P369-V412 VanDerWaalsContact CB-CG1 3.47Å; P369-K419 HydrophobicContact CG-CB 4.04Å; P369-K419 HydrophobicContact CG-CD 4.15Å; P369-I422 HydrophobicContact CG-CG2 4.25Å
370M98.7Very high93.4Very high0 Ų010 Ų100%05%0.054CC..EExtended strand (participates in β ladder)trans-117.3143.6-170.8-71.1173.2-78.800114.4F351 T353 F360 A363 V364 T386 L391 G392 V393 I422F351-M370 HydrophobicContact CB-CG 4.4Å; F351-M370 HydrophobicContact CD1-CG 4.18Å; F351-M370 CarbonylContact O-C 3.55Å; F351-M370 VanDerWaalsContact O-CA 3.22Å; F351-M370 WeakPolarHBondContact O-CA 3.32Å; T353-M370 HydrophobicContact CG2-CB 4.45Å; T353-M370 HydrophobicContact CG2-CG 4.15Å; T353-M370 HydrophobicContact CG2-SD 4.06Å; F360-M370 HydrophobicContact CD2-CE 3.59Å; F360-M370 HydrophobicContact CD2-SD 3.7Å; F360-M370 HydrophobicContact CE2-CE 3.58Å; F360-M370 HydrophobicContact CE2-SD 4.29Å; A363-M370 HydrophobicContact CB-CE 4.06Å; A363-M370 HydrophobicContact CB-CG 3.8Å; A363-M370 HydrophobicContact CB-SD 3.46Å; A363-M370 WeakPolarHBondContact CB-SD 3.23Å; V364-M370 HydrophobicContact CG2-CE 4.39Å; M370-T386 HydrophobicContact CB-CG2 4.02Å; M370-T386 HydrophobicContact CE-CG2 4.27Å; M370-L391 HydrophobicContact CE-CB 3.97Å; M370-L391 HydrophobicContact CE-CD1 4.02Å; M370-L391 PolarHBondContact N-O 3.12Å; M370-G392 WeakPolarHBondContact O-CA 3.19Å; M370-V393 PolarHBondContact O-N 2.87Å; M370-I422 HydrophobicContact CE-CD1 4.26Å
371L98.6Very high93.2Very high0 Ų010.9 Ų10.90%06%0.058CC..EExtended strand (participates in β ladder)trans-106.2100.9156.3177.561.1000107.5L350 F351 I352 T353 I373 V393 L395 F405 I409L350-L371 HydrophobicContact CD1-CB 4.2Å; F351-L371 PolarHBondContact O-N 3.16Å; I352-L371 WeakPolarHBondContact CA-O 3.41Å; I352-L371 HydrophobicContact CB-CB 4.44Å; I352-L371 HydrophobicContact CD1-CD2 4.15Å; I352-L371 HydrophobicContact CG1-CB 4.09Å; I352-L371 HydrophobicContact CG1-CD2 4.15Å; I352-L371 HydrophobicContact CG2-CB 4.36Å; I352-L371 HydrophobicContact CG2-CD2 4.19Å; I352-L371 HydrophobicContact CG2-CG 4.32Å; T353-L371 PolarHBondContact N-O 2.83Å; L371-I373 HydrophobicContact CG-CD1 4.47Å; L371-I373 HydrophobicContact CG-CG1 4.44Å; L371-V393 HydrophobicContact CD1-CG2 3.34Å; L371-L395 HydrophobicContact CD1-CD1 3.8Å; L371-L395 HydrophobicContact CD1-CG 3.8Å; L371-L395 HydrophobicContact CD2-CD1 4.23Å; L371-L395 HydrophobicContact CG-CD1 4.37Å; L371-F405 HydrophobicContact CD2-CD2 4.06Å; L371-F405 HydrophobicContact CD2-CE2 3.85Å; L371-I409 HydrophobicContact CD2-CG1 3.73Å
372S97.5Very high93.1Very high0 Ų010.4 Ų10.40%06%0.056CC..EExtended strand (participates in β ladder)trans-89.9124.5-173.1-68.40000112.1T353 S355 T386 V393 S394 L395T353-S372 CarbonylContact O-C 3.58Å; T353-S372 VanDerWaalsContact O-CA 3.25Å; T353-S372 WeakPolarHBondContact O-CA 3.45Å; S355-S372 WeakPolarHBondContact OG-CB 3.48Å; S355-S372 PolarHBondContact OG-OG 3.45Å; S372-T386 PolarHBondContact OG-OG1 3.03Å; S372-V393 PolarHBondContact N-O 2.96Å; S372-S394 CarbonylContact O-C 3.55Å; S372-S394 WeakPolarHBondContact O-CA 3.45Å; S372-S394 VanDerWaalsContact O-CB 3.31Å; S372-S394 WeakPolarHBondContact O-CB 3.22Å; S372-L395 PolarHBondContact O-N 2.77Å
373I95.9Very high93.1Very high2 Ų210 Ų101%0.015%0.054CC..  trans-130.785.3-179.4-49.1-174.8000109.2F285 I352 T353 H354 L371 L375 L395 K397 L400 F405F285-I373 HydrophobicContact CE1-CB 4.12Å; F285-I373 HydrophobicContact CZ-CB 3.81Å; F285-I373 HydrophobicContact CZ-CD1 4.35Å; F285-I373 HydrophobicContact CZ-CG2 4.13Å; I352-I373 HydrophobicContact CG2-CD1 4.19Å; T353-I373 PolarHBondContact O-N 3.22Å; H354-I373 VanDerWaalsContact CA-O 3.32Å; H354-I373 WeakPolarHBondContact CA-O 3.4Å; L371-I373 HydrophobicContact CG-CD1 4.47Å; L371-I373 HydrophobicContact CG-CG1 4.44Å; I373-L375 PolarHBondContact O-N 3.31Å; I373-L395 HydrophobicContact CD1-CB 4.45Å; I373-L395 HydrophobicContact CD1-CD1 4.35Å; I373-L395 HydrophobicContact CG1-CB 4.2Å; I373-K397 HydrophobicContact CG2-CB 3.85Å; I373-L400 HydrophobicContact CD1-CD1 4.39Å; I373-F405 HydrophobicContact CD1-CD2 3.92Å; I373-F405 HydrophobicContact CD1-CE2 3.69Å
374P93.2Very high92.9Very high19 Ų1910.1 Ų10.112%0.1236%0.055CC..  trans-69.8132.9-172.127.6-33.7000111.8Q379 V380 T383P374-Q379 HydrophobicContact CB-CB 3.92Å; P374-V380 HydrophobicContact CB-CB 4.44Å; P374-V380 HydrophobicContact CB-CG2 3.98Å; P374-V380 HydrophobicContact CG-CG2 4.37Å; P374-T383 HydrophobicContact CG-CG2 4.13Å
375L89.3Confident92.7Very high2 Ų210.1 Ų10.11%0.016%0.055CC..  trans-84.4-51.9174.2-56.8-179.3000110.6I94 W95 G99 F285 A289 H354 I373 Q379 K397I94-L375 HydrophobicContact CG2-CB 3.72Å; W95-L375 HydrophobicContact CD2-CD2 4.43Å; W95-L375 HydrophobicContact CE3-CD2 3.89Å; W95-L375 HydrophobicContact CH2-CD1 4.48Å; W95-L375 HydrophobicContact CH2-CD2 4.14Å; W95-L375 HydrophobicContact CZ2-CD1 4.39Å; W95-L375 HydrophobicContact CZ3-CD2 3.73Å; G99-L375 WeakPolarHBondContact CA-O 3.34Å; F285-L375 HydrophobicContact CB-CD1 4.33Å; F285-L375 HydrophobicContact CD2-CD1 4.06Å; F285-L375 HydrophobicContact CD2-CD2 4.13Å; F285-L375 HydrophobicContact CD2-CG 4.35Å; F285-L375 HydrophobicContact CE2-CD2 4.03Å; F285-L375 HydrophobicContact CG-CD1 4.43Å; A289-L375 HydrophobicContact CB-CD1 3.5Å; A289-L375 VanDerWaalsContact CB-CD1 3.5Å; H354-L375 HydrophobicContact CB-CG 4.23Å; I373-L375 PolarHBondContact O-N 3.31Å; L375-Q379 VanDerWaalsContact CB-OE1 3.23Å; L375-K397 HydrophobicContact CD2-CD 3.58Å; L375-K397 PolarHBondContact O-NZ 2.87Å
376F84.3Confident92.7Very high37 Ų379.6 Ų9.616%0.1625%0.051CC..SBendtrans-167167.5-178.665.9-79.3000113.2I86 I94 L288 Q379I86-F376 HydrophobicContact CD1-CE1 4.24Å; I86-F376 HydrophobicContact CD1-CZ 3.77Å; I94-F376 HydrophobicContact CB-CD1 4.32Å; I94-F376 HydrophobicContact CD1-CD1 3.78Å; I94-F376 HydrophobicContact CD1-CE1 3.77Å; I94-F376 HydrophobicContact CD1-CG 4.2Å; I94-F376 HydrophobicContact CD1-CZ 4.2Å; I94-F376 HydrophobicContact CG1-CB 4.32Å; I94-F376 HydrophobicContact CG1-CD1 3.84Å; I94-F376 HydrophobicContact CG1-CE1 4.35Å; I94-F376 HydrophobicContact CG1-CG 4.08Å; I94-F376 HydrophobicContact CG2-CD1 3.5Å; I94-F376 VanDerWaalsContact CG2-CD1 3.5Å; I94-F376 HydrophobicContact CG2-CE1 4.08Å; I94-F376 HydrophobicContact CG2-CG 4.36Å; L288-F376 HydrophobicContact CB-CZ 4.3Å; L288-F376 HydrophobicContact CD1-CZ 4.05Å; F376-Q379 VanDerWaalsContact N-OE1 3.12Å; F376-Q379 WeakPolarHBondContact O-CB 3.17Å; F376-Q379 WeakPolarHBondContact O-CG 3.06Å; F376-Q379 PolarHBondContact O-N 2.72Å; F376-Q379 PolarHBondContact O-NE2 2.98Å; F376-Q379 PolarHBondContact O-OE1 3.34Å
377G80.1Confident92.6Very high7 Ų711.9 Ų11.97%0.0726%0.061CC..THydrogen-bonded Turntrans65.9-136.5167.900000114.3Q379 V380G377-Q379 PolarHBondContact O-N 3.32Å; G377-V380 PolarHBondContact O-N 2.82Å
378D82Confident92.3Very high35 Ų3514.6 Ų14.619%0.1877%0.071CC..Hα-helixtrans-61.3-23.9-177.969-43.3000113.6L163 V380 R381 N382L163-D378 HydrophobicContact CD1-CB 3.2Å; L163-D378 HydrophobicContact CG-CB 3.7Å; D378-V380 VanDerWaalsContact C-N 3.27Å; D378-V380 PolarHBondContact O-N 3.44Å; D378-R381 WeakPolarHBondContact O-CA 3.39Å; D378-R381 VanDerWaalsContact O-CB 3.23Å; D378-R381 WeakPolarHBondContact O-CB 3.32Å; D378-R381 PolarHBondContact O-N 2.77Å; D378-N382 VanDerWaalsContact O-CG 3.24Å; D378-N382 PolarHBondContact O-N 3.2Å; D378-N382 PolarHBondContact O-ND2 2.8Å; D378-N382 PolarHBondContact OD2-ND2 3.39Å
379Q90.3Very high92.1Very high7 Ų715.1 Ų15.13%0.0337%0.073CC..Hα-helixtrans-56.2-39.3176.7-65.1163.932.600113H354 P374 L375 F376 G377 R381 N382 T383H354-Q379 PolarHBondContact CD2-NE2 3.01Å; H354-Q379 WeakPolarHBondContact O-CB 3.29Å; H354-Q379 WeakPolarHBondContact O-CG 3.45Å; P374-Q379 HydrophobicContact CB-CB 3.92Å; L375-Q379 VanDerWaalsContact CB-OE1 3.23Å; F376-Q379 VanDerWaalsContact N-OE1 3.12Å; F376-Q379 WeakPolarHBondContact O-CB 3.17Å; F376-Q379 WeakPolarHBondContact O-CG 3.06Å; F376-Q379 PolarHBondContact O-N 2.72Å; F376-Q379 PolarHBondContact O-NE2 2.98Å; F376-Q379 PolarHBondContact O-OE1 3.34Å; G377-Q379 PolarHBondContact O-N 3.32Å; Q379-R381 VanDerWaalsContact C-N 3.3Å; Q379-R381 PolarHBondContact O-N 2.67Å; Q379-N382 PolarHBondContact O-N 3.47Å; Q379-T383 VanDerWaalsContact O-CB 3.28Å; Q379-T383 WeakPolarHBondContact O-CB 3.48Å; Q379-T383 PolarHBondContact O-N 3.37Å; Q379-T383 PolarHBondContact O-OG1 3.26Å
380V88.9Confident91.9Very high7 Ų715.4 Ų15.44%0.0428%0.077CC..Hα-helixtrans-60.4-47.3176.4178.10000109.3G99 V100 M184 P374 G377 D378 T383 I384G99-V380 VanDerWaalsContact C-CG2 3.48Å; V100-V380 HydrophobicContact CG2-CG1 3.94Å; M184-V380 WeakPolarHBondContact O-CG1 3.37Å; P374-V380 HydrophobicContact CB-CB 4.44Å; P374-V380 HydrophobicContact CB-CG2 3.98Å; P374-V380 HydrophobicContact CG-CG2 4.37Å; G377-V380 PolarHBondContact O-N 2.82Å; D378-V380 VanDerWaalsContact C-N 3.27Å; D378-V380 PolarHBondContact O-N 3.44Å; V380-T383 WeakPolarHBondContact O-CB 3.3Å; V380-T383 PolarHBondContact O-N 2.83Å; V380-I384 WeakPolarHBondContact O-CG1 3.34Å; V380-I384 PolarHBondContact O-N 3.25Å; V380-I384 VanDerWaalsContact O-N 3.12Å
381R89Confident91.9Very high18 Ų1815.4 Ų15.47%0.0688%0.077CC..Hα-helixtrans-62.5-46.9179.5-163-162.8171.3-78.58.4112L163 L182 D242 D378 Q379 T383 I384 L385L163-R381 HydrophobicContact CD1-CB 4.11Å; L163-R381 HydrophobicContact CD1-CG 4.34Å; L182-R381 HydrophobicContact CD2-CG 3.68Å; L182-R381 HydrophobicContact CG-CG 3.64Å; L182-R381 PolarHBondContact O-NE 2.73Å; D242-R381 IonicContact OD1-CZ 3.47Å; D242-R381 IonicContact OD1-NH1 3Å; D242-R381 PolarHBondContact OD1-NH1 2.9Å; D242-R381 IonicContact OD1-NH2 2.87Å; D242-R381 PolarHBondContact OD1-NH2 2.93Å; D242-R381 IonicContact OD2-CZ 2.5Å; D242-R381 IonicContact OD2-NH1 2.94Å; D242-R381 IonicContact OD2-NH2 3.56Å; D242-R381 PolarHBondContact OD2-NH2 3.08Å; D378-R381 WeakPolarHBondContact O-CA 3.39Å; D378-R381 VanDerWaalsContact O-CB 3.23Å; D378-R381 WeakPolarHBondContact O-CB 3.32Å; D378-R381 PolarHBondContact O-N 2.77Å; Q379-R381 VanDerWaalsContact C-N 3.3Å; Q379-R381 PolarHBondContact O-N 2.67Å; R381-T383 VanDerWaalsContact C-N 3.27Å; R381-T383 PolarHBondContact O-N 3.36Å; R381-I384 WeakPolarHBondContact O-CB 3.32Å; R381-I384 PolarHBondContact O-N 3.5Å; R381-I384 VanDerWaalsContact O-N 3.08Å; R381-L385 PolarHBondContact O-N 2.99Å; R381-L385 VanDerWaalsContact O-N 3.16Å
382N92.3Very high91.9Very high0 Ų015.5 Ų15.50%08%0.078CC..Hα-helixtrans-65.3-33.7178.8-60.8-21.3000111.6M237 S355 I357 F360 D378 Q379 I384 L385 T386M237-N382 WeakPolarHBondContact CE-OD1 3.39Å; S355-N382 WeakPolarHBondContact O-CB 3.41Å; S355-N382 PolarHBondContact O-ND2 3.14Å; I357-N382 PolarHBondContact N-ND2 3.27Å; F360-N382 HydrophobicContact CD1-CB 4.45Å; F360-N382 HydrophobicContact CG-CB 4.44Å; D378-N382 VanDerWaalsContact O-CG 3.24Å; D378-N382 PolarHBondContact O-N 3.2Å; D378-N382 PolarHBondContact O-ND2 2.8Å; D378-N382 PolarHBondContact OD2-ND2 3.39Å; Q379-N382 PolarHBondContact O-N 3.47Å; N382-I384 VanDerWaalsContact C-N 3.29Å; N382-I384 PolarHBondContact O-N 3.48Å; N382-L385 WeakPolarHBondContact O-CA 3.3Å; N382-L385 WeakPolarHBondContact O-CB 3.43Å; N382-L385 PolarHBondContact O-N 2.94Å; N382-L385 VanDerWaalsContact O-N 3.1Å; N382-T386 PolarHBondContact O-N 2.63Å; N382-T386 PolarHBondContact O-OG1 3.41Å
383T94Very high91.8Very high4 Ų416.7 Ų16.73%0.0259%0.085CC..Hα-helixtrans-62.3-36.6172-66.70000112.1P374 Q379 V380 R381 L385 T386 K387P374-T383 HydrophobicContact CG-CG2 4.13Å; Q379-T383 VanDerWaalsContact O-CB 3.28Å; Q379-T383 WeakPolarHBondContact O-CB 3.48Å; Q379-T383 PolarHBondContact O-N 3.37Å; Q379-T383 PolarHBondContact O-OG1 3.26Å; V380-T383 WeakPolarHBondContact O-CB 3.3Å; V380-T383 PolarHBondContact O-N 2.83Å; R381-T383 VanDerWaalsContact C-N 3.27Å; R381-T383 PolarHBondContact O-N 3.36Å; T383-L385 VanDerWaalsContact C-N 3.31Å; T383-T386 WeakPolarHBondContact O-CB 3.33Å; T383-T386 PolarHBondContact O-N 3.4Å; T383-K387 PolarHBondContact O-N 2.98Å
384I92.9Very high91.8Very high3 Ų317.8 Ų17.82%0.0159%0.094CC..Hα-helixtrans-66-37.8173.3-59.2160.8000110.4L182 M186 V380 R381 N382 K387 F388L182-I384 HydrophobicContact CD1-CB 4.24Å; L182-I384 HydrophobicContact CD1-CD1 3.66Å; L182-I384 HydrophobicContact CD1-CG2 3.87Å; L182-I384 HydrophobicContact CD2-CB 4.41Å; L182-I384 HydrophobicContact CD2-CG2 4.37Å; M186-I384 HydrophobicContact CB-CD1 3.82Å; M186-I384 VanDerWaalsContact O-CD1 3.25Å; M186-I384 WeakPolarHBondContact O-CD1 3.24Å; V380-I384 WeakPolarHBondContact O-CG1 3.34Å; V380-I384 PolarHBondContact O-N 3.25Å; V380-I384 VanDerWaalsContact O-N 3.12Å; R381-I384 WeakPolarHBondContact O-CB 3.32Å; R381-I384 PolarHBondContact O-N 3.5Å; R381-I384 VanDerWaalsContact O-N 3.08Å; N382-I384 VanDerWaalsContact C-N 3.29Å; N382-I384 PolarHBondContact O-N 3.48Å; I384-K387 PolarHBondContact O-N 3.22Å; I384-F388 VanDerWaalsContact O-CB 3.23Å; I384-F388 WeakPolarHBondContact O-CB 3.43Å; I384-F388 PolarHBondContact O-N 3.45Å
385L93.2Very high91.9Very high0 Ų018.5 Ų18.50%010%0.096CC..Hα-helixtrans-62.6-39.3173.8-63.8178.7000112.3L182 M237 I243 F360 R381 N382 T383 K387 F388 H389L182-L385 HydrophobicContact CD2-CD2 3.81Å; L182-L385 HydrophobicContact CD2-CG 4.16Å; M237-L385 HydrophobicContact CE-CD1 4.16Å; M237-L385 HydrophobicContact SD-CD1 3.64Å; I243-L385 HydrophobicContact CD1-CD2 3.91Å; I243-L385 HydrophobicContact CG1-CD2 4.06Å; F360-L385 HydrophobicContact CE1-CB 4.15Å; F360-L385 HydrophobicContact CE1-CD1 4.02Å; F360-L385 HydrophobicContact CE2-CB 4.48Å; F360-L385 HydrophobicContact CZ-CB 3.67Å; F360-L385 HydrophobicContact CZ-CD1 4.39Å; R381-L385 PolarHBondContact O-N 2.99Å; R381-L385 VanDerWaalsContact O-N 3.16Å; N382-L385 WeakPolarHBondContact O-CA 3.3Å; N382-L385 WeakPolarHBondContact O-CB 3.43Å; N382-L385 PolarHBondContact O-N 2.94Å; N382-L385 VanDerWaalsContact O-N 3.1Å; T383-L385 VanDerWaalsContact C-N 3.31Å; L385-K387 VanDerWaalsContact C-N 3.3Å; L385-K387 PolarHBondContact O-N 2.95Å; L385-F388 PolarHBondContact O-N 3.11Å; L385-H389 PolarHBondContact O-CD2 3.11Å; L385-H389 PolarHBondContact O-N 3.16Å
386T95.5Very high92Very high0 Ų019.9 Ų19.90%010%0.104CC..Hα-helixtrans-52.6-48.8171.3-600000110.9F360 M370 S372 N382 T383 G390 L391F360-T386 WeakPolarHBondContact CE2-OG1 3.49Å; M370-T386 HydrophobicContact CB-CG2 4.02Å; M370-T386 HydrophobicContact CE-CG2 4.27Å; S372-T386 PolarHBondContact OG-OG1 3.03Å; N382-T386 PolarHBondContact O-N 2.63Å; N382-T386 PolarHBondContact O-OG1 3.41Å; T383-T386 WeakPolarHBondContact O-CB 3.33Å; T383-T386 PolarHBondContact O-N 3.4Å; T386-G390 PolarHBondContact O-N 3.05Å; T386-L391 HydrophobicContact CG2-CB 4.2Å; T386-L391 PolarHBondContact O-N 3.33Å
387K94.1Very high92.4Very high90 Ų9018.3 Ų18.339%0.39110%0.096SC..Hα-helixtrans-69.8-43.7178.6-78.2179.6162.31700112.5T383 I384 L385 H389 G390 S394T383-K387 PolarHBondContact O-N 2.98Å; I384-K387 PolarHBondContact O-N 3.22Å; L385-K387 VanDerWaalsContact C-N 3.3Å; L385-K387 PolarHBondContact O-N 2.95Å; K387-H389 PolarHBondContact O-N 3.19Å; K387-G390 PolarHBondContact O-N 2.96Å; K387-S394 WeakPolarHBondContact CE-OG 3.27Å; K387-S394 PolarHBondContact NZ-OG 2.97Å
388F92Very high92.9Very high69 Ų6920.6 Ų20.630%0.30311%0.109SC..Hα-helixtrans-60.8-43.7-176.4171.8-100.7000112.3Y189 I243 I384 L385 G390 K715Y189-F388 AromaticContact CD1-CD2 3.84Å; Y189-F388 HydrophobicContact CD1-CD2 3.84Å; Y189-F388 AromaticContact CD1-CE2 3.89Å; Y189-F388 HydrophobicContact CD1-CE2 3.89Å; Y189-F388 HydrophobicContact CE1-CE2 4.2Å; I243-F388 HydrophobicContact CD1-CD1 3.69Å; I243-F388 HydrophobicContact CD1-CD2 4.16Å; I243-F388 HydrophobicContact CD1-CE1 3.51Å; I243-F388 HydrophobicContact CD1-CE2 4Å; I243-F388 HydrophobicContact CD1-CG 4.01Å; I243-F388 HydrophobicContact CD1-CZ 3.67Å; I384-F388 VanDerWaalsContact O-CB 3.23Å; I384-F388 WeakPolarHBondContact O-CB 3.43Å; I384-F388 PolarHBondContact O-N 3.45Å; L385-F388 PolarHBondContact O-N 3.11Å; F388-G390 VanDerWaalsContact C-N 3.27Å; F388-K715 VanDerWaalsContact CZ-CE 3.45Å
389H93.3Very high93.4Very high11 Ų1125.9 Ų25.95%0.05113%0.126CC..THydrogen-bonded Turntrans-84.2-2.5175-66-69.1000113.1M240 L241 L385 K387 L391 L425 H711M240-H389 PolarHBondContact O-CE1 2.79Å; L241-H389 PolarHBondContact O-NE2 2.73Å; L385-H389 PolarHBondContact O-CD2 3.11Å; L385-H389 PolarHBondContact O-N 3.16Å; K387-H389 PolarHBondContact O-N 3.19Å; H389-L391 HydrophobicContact CB-CD1 3.94Å; H389-L391 HydrophobicContact CB-CD2 3.79Å; H389-L391 HydrophobicContact CB-CG 3.63Å; H389-L425 HydrophobicContact CB-CD2 4.16Å; H389-H711 AromaticContact CE1-ND1 3.71Å; H389-H711 AromaticContact ND1-CE1 3.6Å; H389-H711 AromaticContact ND1-ND1 3.24Å; H389-H711 PolarHBondContact ND1-ND1 2.89Å
390G95.6Very high93.7Very high12 Ų1226.4 Ų26.412%0.12413%0.129CC..THydrogen-bonded Turntrans61.546.5-17800000112.5T386 K387 F388 Y418 R421T386-G390 PolarHBondContact O-N 3.05Å; K387-G390 PolarHBondContact O-N 2.96Å; F388-G390 VanDerWaalsContact C-N 3.27Å; G390-Y418 WeakPolarHBondContact O-CD1 3.37Å; G390-R421 PolarHBondContact O-NE 3.4Å; G390-R421 PolarHBondContact O-NH2 2.9Å
391L97.7Very high94.1Very high0 Ų029 Ų290%015%0.146CC..SBendtrans-95.1-6.2-179.5-46.7-180000112.7F360 V364 P369 M370 T386 H389 I422 L425F360-L391 HydrophobicContact CE2-CD1 4.23Å; F360-L391 HydrophobicContact CZ-CD1 4.4Å; V364-L391 HydrophobicContact CG2-CD1 3.9Å; P369-L391 WeakPolarHBondContact CA-O 3.43Å; M370-L391 HydrophobicContact CE-CB 3.97Å; M370-L391 HydrophobicContact CE-CD1 4.02Å; M370-L391 PolarHBondContact N-O 3.12Å; T386-L391 HydrophobicContact CG2-CB 4.2Å; T386-L391 PolarHBondContact O-N 3.33Å; H389-L391 HydrophobicContact CB-CD1 3.94Å; H389-L391 HydrophobicContact CB-CD2 3.79Å; H389-L391 HydrophobicContact CB-CG 3.63Å; L391-I422 HydrophobicContact CB-CD1 4.33Å; L391-I422 HydrophobicContact CD1-CG1 4.48Å; L391-I422 HydrophobicContact CD2-CB 3.8Å; L391-I422 HydrophobicContact CD2-CG1 3.99Å; L391-L425 HydrophobicContact CD1-CD2 3.81Å; L391-L425 HydrophobicContact CD2-CD2 3.92Å; L391-L425 HydrophobicContact CG-CD2 4.45Å
392G97.9Very high94.5Very high3 Ų331.9 Ų31.93%0.03116%0.16CC..EExtended strand (participates in β ladder)trans168.6-165.3-177.500000112.5M370 Y418M370-G392 WeakPolarHBondContact O-CA 3.19Å; G392-Y418 VanDerWaalsContact CA-CD1 3.48Å; G392-Y418 WeakPolarHBondContact O-CE1 3.32Å
393V97.1Very high94.8Very high24 Ų2437.3 Ų37.315%0.14519%0.185CC..EExtended strand (participates in β ladder)trans-113.9168.6174.6-54.90000110.3M370 L371 S372 S411 V412 Y418M370-V393 PolarHBondContact O-N 2.87Å; L371-V393 HydrophobicContact CD1-CG2 3.34Å; S372-V393 PolarHBondContact N-O 2.96Å; V393-S411 WeakPolarHBondContact CG1-OG 3.37Å; V393-V412 HydrophobicContact CB-CG2 4.31Å; V393-V412 HydrophobicContact CG1-CG2 4.09Å; V393-V412 HydrophobicContact CG2-CG2 3.65Å; V393-Y418 HydrophobicContact CG1-CE2 4.26Å; V393-Y418 VanDerWaalsContact CG1-OH 3.27Å; V393-Y418 WeakPolarHBondContact CG1-OH 3.4Å
394S95.4Very high95Very high26 Ų2639.6 Ų39.618%0.18220%0.199CC..EExtended strand (participates in β ladder)trans-131.6144.4173.490.30000112.4S372 K387S372-S394 CarbonylContact O-C 3.55Å; S372-S394 WeakPolarHBondContact O-CA 3.45Å; S372-S394 VanDerWaalsContact O-CB 3.31Å; S372-S394 WeakPolarHBondContact O-CB 3.22Å; K387-S394 WeakPolarHBondContact CE-OG 3.27Å; K387-S394 PolarHBondContact NZ-OG 2.97Å
395L95.1Very high95.3Very high34 Ų3439.4 Ų39.418%0.17820%0.198CC..  trans-117.7155.4176.5-57.7177.5000110.7L371 S372 I373 L400 F405L371-L395 HydrophobicContact CD1-CD1 3.8Å; L371-L395 HydrophobicContact CD1-CG 3.8Å; L371-L395 HydrophobicContact CD2-CD1 4.23Å; L371-L395 HydrophobicContact CG-CD1 4.37Å; S372-L395 PolarHBondContact O-N 2.77Å; I373-L395 HydrophobicContact CD1-CB 4.45Å; I373-L395 HydrophobicContact CD1-CD1 4.35Å; I373-L395 HydrophobicContact CG1-CB 4.2Å; L395-L400 HydrophobicContact CB-CD1 4.08Å; L395-L400 HydrophobicContact CD1-CD1 3.68Å; L395-F405 HydrophobicContact CD1-CD2 4.12Å
396D91.9Very high95.5Very high31 Ų3142 Ų4217%0.16621%0.208CC..  trans-99.8114.5173.5176.1-2.6000108.3R98 T398 R399 L400R98-D396 IonicContact CZ-OD2 3.2Å; R98-D396 IonicContact NE-OD2 2.56Å; R98-D396 PolarHBondContact NE-OD2 2.83Å; R98-D396 IonicContact NH2-OD2 3.69Å; D396-T398 PolarHBondContact O-N 2.94Å; D396-T398 VanDerWaalsContact O-N 3.11Å; D396-T398 PolarHBondContact OD1-N 2.81Å; D396-T398 PolarHBondContact OD1-OG1 3.12Å; D396-T398 PolarHBondContact OD2-OG1 2.79Å; D396-R399 CarbonylContact O-C 3.59Å; D396-R399 PolarHBondContact O-N 3.08Å; D396-R399 IonicContact OD2-CZ 2.77Å; D396-R399 IonicContact OD2-NE 3.42Å; D396-R399 PolarHBondContact OD2-NE 3.2Å; D396-R399 IonicContact OD2-NH2 3.63Å; D396-R399 PolarHBondContact OD2-NH2 3.4Å; D396-L400 PolarHBondContact O-N 3.31Å
397K92.1Very high95.7Very high3 Ų347.8 Ų47.81%0.01323%0.234CC..G310 helixtrans-57.5-27.6-177.969.8-173.5-168.3-78.70113.9I94 W95 R97 I298 I373 L375 R399 L400I94-K397 WeakPolarHBondContact O-CE 3.17Å; I94-K397 PolarHBondContact O-NZ 3.25Å; W95-K397 WeakPolarHBondContact O-CE 3.5Å; R97-K397 VanDerWaalsContact O-CE 3.29Å; R97-K397 WeakPolarHBondContact O-CE 3.34Å; R97-K397 PolarHBondContact O-NZ 2.7Å; I298-K397 VanDerWaalsContact CD1-O 3.26Å; I298-K397 WeakPolarHBondContact CD1-O 3.22Å; I373-K397 HydrophobicContact CG2-CB 3.85Å; L375-K397 HydrophobicContact CD2-CD 3.58Å; L375-K397 PolarHBondContact O-NZ 2.87Å; K397-R399 PolarHBondContact O-N 3.48Å; K397-L400 WeakPolarHBondContact O-CB 3.46Å; K397-L400 PolarHBondContact O-N 2.79Å
398T90.8Very high95.9Very high55 Ų5543.8 Ų43.834%0.33722%0.217SC..G310 helixtrans-74.2-12.9179.464.10000113.5R97 R98 D396R97-T398 VanDerWaalsContact C-CG2 3.46Å; R98-T398 HydrophobicContact CG-CG2 3.95Å; D396-T398 PolarHBondContact O-N 2.94Å; D396-T398 VanDerWaalsContact O-N 3.11Å; D396-T398 PolarHBondContact OD1-N 2.81Å; D396-T398 PolarHBondContact OD1-OG1 3.12Å; D396-T398 PolarHBondContact OD2-OG1 2.79Å
399R92.4Very high96.2Very high146 Ų14640.5 Ų40.555%0.55120%0.203SC*.G310 helixtrans-120.317.2177.3-65.9-178.6-75.1166.2-1.1111.3D396 K397 T401D396-R399 CarbonylContact O-C 3.59Å; D396-R399 PolarHBondContact O-N 3.08Å; D396-R399 IonicContact OD2-CZ 2.77Å; D396-R399 IonicContact OD2-NE 3.42Å; D396-R399 PolarHBondContact OD2-NE 3.2Å; D396-R399 IonicContact OD2-NH2 3.63Å; D396-R399 PolarHBondContact OD2-NH2 3.4Å; K397-R399 PolarHBondContact O-N 3.48Å; R399-T401 PolarHBondContact O-N 3.41Å
400L95.9Very high96.5Very high18 Ų1841.4 Ų41.49%0.09421%0.208CC..  trans-74.8128.6-178-159.277000109.7I298 I302 I373 L395 D396 K397 F405I298-L400 HydrophobicContact CG2-CD2 4.04Å; I302-L400 HydrophobicContact CD1-CD2 3.95Å; I302-L400 HydrophobicContact CG1-CD2 3.81Å; I373-L400 HydrophobicContact CD1-CD1 4.39Å; L395-L400 HydrophobicContact CB-CD1 4.08Å; L395-L400 HydrophobicContact CD1-CD1 3.68Å; D396-L400 PolarHBondContact O-N 3.31Å; K397-L400 WeakPolarHBondContact O-CB 3.46Å; K397-L400 PolarHBondContact O-N 2.79Å; L400-F405 HydrophobicContact CD1-CB 3.99Å; L400-F405 HydrophobicContact CD1-CD2 3.99Å; L400-F405 HydrophobicContact CD1-CG 4.43Å; L400-F405 HydrophobicContact CD2-CD2 4.2Å; L400-F405 HydrophobicContact CG-CB 4.21Å
401T97.8Very high96.6Very high63 Ų6343 Ų4339%0.38722%0.217SC..  trans-131.816517463.80000107.8R399 E403 T404 F405R399-T401 PolarHBondContact O-N 3.41Å; T401-E403 VanDerWaalsContact C-N 3.26Å; T401-E403 PolarHBondContact O-N 2.83Å; T401-T404 PolarHBondContact N-OG1 3.43Å; T401-T404 PolarHBondContact O-N 3.26Å; T401-T404 PolarHBondContact O-OG1 3.3Å; T401-T404 WeakPolarHBondContact OG1-CG2 3.14Å; T401-T404 PolarHBondContact OG1-N 3.49Å; T401-T404 VanDerWaalsContact OG1-N 3.13Å; T401-T404 PolarHBondContact OG1-OG1 2.87Å; T401-F405 WeakPolarHBondContact O-CB 3.48Å; T401-F405 PolarHBondContact O-N 2.87Å
402E98.1Very high96.6Very high78 Ų7843.2 Ų43.236%0.36422%0.219SC..Hα-helixtrans-51.8-49.5174.2178.2-177.9173.400110.8A301 A304 A305 Q308 F405 Y406A301-E402 HydrophobicContact CB-CB 4.43Å; A301-E402 WeakPolarHBondContact O-CA 3.46Å; A304-E402 VanDerWaalsContact CB-CD 3.4Å; A304-E402 HydrophobicContact CB-CG 3.88Å; A305-E402 HydrophobicContact CB-CG 4.1Å; Q308-E402 PolarHBondContact NE2-OE1 2.58Å; E402-F405 PolarHBondContact O-N 3.4Å; E402-Y406 VanDerWaalsContact O-CB 3.22Å; E402-Y406 WeakPolarHBondContact O-CB 3.35Å; E402-Y406 PolarHBondContact O-N 2.76Å
403E98.3Very high96.7Very high114 Ų11444.8 Ų44.853%0.53323%0.226SC..Hα-helixtrans-61.8-47.4-179.6-172.4-167.9165.600112.7T401 K407T401-E403 VanDerWaalsContact C-N 3.26Å; T401-E403 PolarHBondContact O-N 2.83Å; E403-K407 HydrophobicContact CG-CD 4.04Å; E403-K407 VanDerWaalsContact O-CB 3.28Å; E403-K407 WeakPolarHBondContact O-CB 3.38Å; E403-K407 VanDerWaalsContact O-CG 3.29Å; E403-K407 WeakPolarHBondContact O-CG 3.33Å; E403-K407 PolarHBondContact O-N 3.14Å; E403-K407 VanDerWaalsContact OE1-CE 3.29Å; E403-K407 WeakPolarHBondContact OE1-CE 3.39Å; E403-K407 IonicContact OE1-NZ 3.36Å; E403-K407 PolarHBondContact OE1-NZ 3.08Å
404T98.2Very high96.7Very high51 Ų5150.1 Ų50.131%0.31325%0.249SC..Hα-helixtrans-69.7-35.4-177.1530000111.8T401 G408T401-T404 PolarHBondContact N-OG1 3.43Å; T401-T404 PolarHBondContact O-N 3.26Å; T401-T404 PolarHBondContact O-OG1 3.3Å; T401-T404 WeakPolarHBondContact OG1-CG2 3.14Å; T401-T404 PolarHBondContact OG1-N 3.49Å; T401-T404 VanDerWaalsContact OG1-N 3.13Å; T401-T404 PolarHBondContact OG1-OG1 2.87Å; T404-G408 PolarHBondContact O-N 2.88Å
405F98.6Very high96.8Very high0 Ų052.1 Ų52.10%026%0.258CS..Hα-helixtrans-69.1-48.1174.8-172.8-110.6000111.5F283 I302 A305 F306 I352 L371 I373 L395 L400 T401 E402 K407 G408 I409F283-F405 HydrophobicContact CD1-CZ 4.12Å; F283-F405 HydrophobicContact CE1-CE2 4.14Å; F283-F405 AromaticContact CE1-CZ 3.66Å; F283-F405 HydrophobicContact CE1-CZ 3.66Å; I302-F405 HydrophobicContact CB-CD1 4.48Å; I302-F405 HydrophobicContact CB-CE1 4.17Å; I302-F405 HydrophobicContact CG1-CD1 4.24Å; I302-F405 HydrophobicContact CG1-CD2 4.45Å; I302-F405 HydrophobicContact CG1-CE1 4.09Å; I302-F405 HydrophobicContact CG1-CE2 4.31Å; I302-F405 HydrophobicContact CG1-CG 4.4Å; I302-F405 HydrophobicContact CG1-CZ 4.12Å; I302-F405 HydrophobicContact CG2-CE1 3.81Å; I302-F405 HydrophobicContact CG2-CZ 4.02Å; A305-F405 HydrophobicContact CB-CD1 3.65Å; A305-F405 HydrophobicContact CB-CE1 4.42Å; F306-F405 AromaticContact CD1-CE1 3.98Å; F306-F405 HydrophobicContact CD1-CE1 3.98Å; F306-F405 AromaticContact CE1-CE1 3.59Å; F306-F405 HydrophobicContact CE1-CE1 3.59Å; F306-F405 AromaticContact CE1-CZ 3.96Å; F306-F405 HydrophobicContact CE1-CZ 3.96Å; F306-F405 AromaticContact CZ-CE1 3.96Å; F306-F405 HydrophobicContact CZ-CE1 3.96Å; F306-F405 AromaticContact CZ-CZ 4Å; F306-F405 HydrophobicContact CZ-CZ 4Å; I352-F405 HydrophobicContact CD1-CE1 4.41Å; I352-F405 HydrophobicContact CD1-CE2 4.14Å; I352-F405 HydrophobicContact CD1-CZ 3.59Å; I352-F405 HydrophobicContact CG2-CE2 4Å; I352-F405 HydrophobicContact CG2-CZ 4.25Å; L371-F405 HydrophobicContact CD2-CD2 4.06Å; L371-F405 HydrophobicContact CD2-CE2 3.85Å; I373-F405 HydrophobicContact CD1-CD2 3.92Å; I373-F405 HydrophobicContact CD1-CE2 3.69Å; L395-F405 HydrophobicContact CD1-CD2 4.12Å; L400-F405 HydrophobicContact CD1-CB 3.99Å; L400-F405 HydrophobicContact CD1-CD2 3.99Å; L400-F405 HydrophobicContact CD1-CG 4.43Å; L400-F405 HydrophobicContact CD2-CD2 4.2Å; L400-F405 HydrophobicContact CG-CB 4.21Å; T401-F405 WeakPolarHBondContact O-CB 3.48Å; T401-F405 PolarHBondContact O-N 2.87Å; E402-F405 PolarHBondContact O-N 3.4Å; F405-K407 PolarHBondContact O-N 3.26Å; F405-G408 WeakPolarHBondContact O-CA 3.35Å; F405-G408 PolarHBondContact O-N 3.36Å; F405-G408 VanDerWaalsContact O-N 3.13Å; F405-I409 HydrophobicContact CD1-CD1 3.88Å; F405-I409 HydrophobicContact CE1-CD1 3.59Å; F405-I409 HydrophobicContact CZ-CD1 4.06Å; F405-I409 WeakPolarHBondContact O-CG1 3.45Å; F405-I409 PolarHBondContact O-N 3.49Å
406Y98.7Very high96.9Very high55 Ų5554.1 Ų54.122%0.21628%0.275CS..Hα-helixtrans-58-49.6176179.1-103.4000112.1Q308 L309 E402 G408 I409 L410Q308-Y406 HydrophobicContact CB-CD2 3.85Å; Q308-Y406 HydrophobicContact CB-CE2 3.5Å; Q308-Y406 VanDerWaalsContact CB-CE2 3.5Å; L309-Y406 HydrophobicContact CD2-CD2 4.33Å; L309-Y406 HydrophobicContact CD2-CE2 3.69Å; L309-Y406 HydrophobicContact CG-CD2 4.24Å; L309-Y406 HydrophobicContact CG-CE2 3.93Å; E402-Y406 VanDerWaalsContact O-CB 3.22Å; E402-Y406 WeakPolarHBondContact O-CB 3.35Å; E402-Y406 PolarHBondContact O-N 2.76Å; Y406-G408 VanDerWaalsContact C-N 3.29Å; Y406-G408 PolarHBondContact O-N 3.43Å; Y406-I409 WeakPolarHBondContact O-CB 3.3Å; Y406-I409 PolarHBondContact O-N 2.82Å; Y406-L410 HydrophobicContact CD1-CD1 4.04Å; Y406-L410 HydrophobicContact CD1-CG 4.46Å; Y406-L410 HydrophobicContact CE1-CD1 3.34Å; Y406-L410 HydrophobicContact CE1-CG 4.09Å; Y406-L410 HydrophobicContact CE2-CD1 4.37Å; Y406-L410 HydrophobicContact CE2-CG 4.43Å; Y406-L410 PolarHBondContact O-N 2.81Å
407K98.5Very high97.2Very high121 Ų12153 Ų5353%0.52627%0.271SS..Hα-helixtrans-60.8-38.5174.8-74.6179.7175.5178.50111.9E403 F405 L410 S411E403-K407 HydrophobicContact CG-CD 4.04Å; E403-K407 VanDerWaalsContact O-CB 3.28Å; E403-K407 WeakPolarHBondContact O-CB 3.38Å; E403-K407 VanDerWaalsContact O-CG 3.29Å; E403-K407 WeakPolarHBondContact O-CG 3.33Å; E403-K407 PolarHBondContact O-N 3.14Å; E403-K407 VanDerWaalsContact OE1-CE 3.29Å; E403-K407 WeakPolarHBondContact OE1-CE 3.39Å; E403-K407 IonicContact OE1-NZ 3.36Å; E403-K407 PolarHBondContact OE1-NZ 3.08Å; F405-K407 PolarHBondContact O-N 3.26Å; K407-L410 PolarHBondContact O-N 3.27Å; K407-S411 VanDerWaalsContact O-CB 3.3Å; K407-S411 WeakPolarHBondContact O-CB 3.3Å; K407-S411 PolarHBondContact O-N 2.87Å
408G98.4Very high97.5Very high5 Ų554.6 Ų54.65%0.05228%0.277CS..Hα-helixtrans-57.4-48.5174.200000112.1T404 F405 Y406 S411 V412T404-G408 PolarHBondContact O-N 2.88Å; F405-G408 WeakPolarHBondContact O-CA 3.35Å; F405-G408 PolarHBondContact O-N 3.36Å; F405-G408 VanDerWaalsContact O-N 3.13Å; Y406-G408 VanDerWaalsContact C-N 3.29Å; Y406-G408 PolarHBondContact O-N 3.43Å; G408-S411 PolarHBondContact O-N 3.46Å; G408-S411 PolarHBondContact O-OG 3.12Å; G408-V412 PolarHBondContact O-N 3.44Å
409I98.8Very high97.9Very high0 Ų056.2 Ų56.20%028%0.279CS..Hα-helixtrans-58.6-54.3175.7-69.2167.6000110.7I281 F306 L309 L350 I352 L371 F405 Y406 S411 V412 L413I281-I409 HydrophobicContact CD1-CG2 4.03Å; F306-I409 HydrophobicContact CD1-CD1 4.04Å; F306-I409 HydrophobicContact CE1-CD1 3.7Å; L309-I409 HydrophobicContact CD1-CB 4.47Å; L309-I409 HydrophobicContact CD1-CD1 3.85Å; L309-I409 HydrophobicContact CD1-CG2 3.76Å; L350-I409 HydrophobicContact CD2-CB 4.19Å; L350-I409 HydrophobicContact CD2-CG1 4.11Å; L350-I409 HydrophobicContact CD2-CG2 3.75Å; I352-I409 HydrophobicContact CD1-CD1 4Å; I352-I409 HydrophobicContact CD1-CG1 4.01Å; L371-I409 HydrophobicContact CD2-CG1 3.73Å; F405-I409 HydrophobicContact CD1-CD1 3.88Å; F405-I409 HydrophobicContact CE1-CD1 3.59Å; F405-I409 HydrophobicContact CZ-CD1 4.06Å; F405-I409 WeakPolarHBondContact O-CG1 3.45Å; F405-I409 PolarHBondContact O-N 3.49Å; Y406-I409 WeakPolarHBondContact O-CB 3.3Å; Y406-I409 PolarHBondContact O-N 2.82Å; I409-S411 VanDerWaalsContact C-N 3.28Å; I409-S411 PolarHBondContact O-N 3.16Å; I409-V412 PolarHBondContact O-N 2.75Å; I409-V412 VanDerWaalsContact O-N 3.16Å; I409-L413 HydrophobicContact CG2-CD1 3.49Å; I409-L413 VanDerWaalsContact CG2-CD1 3.49Å; I409-L413 HydrophobicContact CG2-CG 4.18Å; I409-L413 WeakPolarHBondContact O-CG 3.27Å; I409-L413 PolarHBondContact O-N 3.15Å
410L98.5Very high98.1Very high30 Ų3054.7 Ų54.716%0.15728%0.278CS..Hα-helixtrans-61.4-36.6-178-67.8-170.2000112.6L309 Y406 K407 V412 L413 H414L309-L410 HydrophobicContact CD2-CD2 4.05Å; Y406-L410 HydrophobicContact CD1-CD1 4.04Å; Y406-L410 HydrophobicContact CD1-CG 4.46Å; Y406-L410 HydrophobicContact CE1-CD1 3.34Å; Y406-L410 HydrophobicContact CE1-CG 4.09Å; Y406-L410 HydrophobicContact CE2-CD1 4.37Å; Y406-L410 HydrophobicContact CE2-CG 4.43Å; Y406-L410 PolarHBondContact O-N 2.81Å; K407-L410 PolarHBondContact O-N 3.27Å; L410-V412 PolarHBondContact O-N 3.41Å; L410-L413 PolarHBondContact O-N 2.87Å; L410-H414 VanDerWaalsContact O-CB 3.28Å; L410-H414 WeakPolarHBondContact O-CB 2.96Å; L410-H414 VanDerWaalsContact O-CG 3.29Å; L410-H414 PolarHBondContact O-N 2.79Å
411S98.3Very high98.2Very high46 Ų4658.7 Ų58.732%0.32229%0.292SS..Hα-helixtrans-60.9-32.1179.576.40000113V393 K407 G408 I409 N415 Y418V393-S411 WeakPolarHBondContact CG1-OG 3.37Å; K407-S411 VanDerWaalsContact O-CB 3.3Å; K407-S411 WeakPolarHBondContact O-CB 3.3Å; K407-S411 PolarHBondContact O-N 2.87Å; G408-S411 PolarHBondContact O-N 3.46Å; G408-S411 PolarHBondContact O-OG 3.12Å; I409-S411 VanDerWaalsContact C-N 3.28Å; I409-S411 PolarHBondContact O-N 3.16Å; S411-N415 WeakPolarHBondContact O-CB 3.28Å; S411-Y418 WeakPolarHBondContact O-CE2 3.45Å
412V98.6Very high98.2Very high5 Ų555.7 Ų55.73%0.0327%0.274CS..Hα-helixtrans-82.8-46176.6-175.90000110.3L350 P369 V393 G408 I409 L410 H414 N415 Y418L350-V412 HydrophobicContact CD1-CB 3.92Å; L350-V412 HydrophobicContact CD1-CG1 3.64Å; L350-V412 HydrophobicContact CD1-CG2 4.38Å; P369-V412 HydrophobicContact CB-CG1 3.47Å; P369-V412 VanDerWaalsContact CB-CG1 3.47Å; V393-V412 HydrophobicContact CB-CG2 4.31Å; V393-V412 HydrophobicContact CG1-CG2 4.09Å; V393-V412 HydrophobicContact CG2-CG2 3.65Å; G408-V412 PolarHBondContact O-N 3.44Å; I409-V412 PolarHBondContact O-N 2.75Å; I409-V412 VanDerWaalsContact O-N 3.16Å; L410-V412 PolarHBondContact O-N 3.41Å; V412-H414 VanDerWaalsContact C-N 3.35Å; V412-H414 PolarHBondContact O-N 3.06Å; V412-N415 PolarHBondContact O-N 3.49Å; V412-Y418 HydrophobicContact CB-CD2 4.39Å; V412-Y418 HydrophobicContact CG1-CD2 4.11Å; V412-Y418 HydrophobicContact CG1-CG 4.48Å
413L98.2Very high98.1Very high35 Ų3555.2 Ų55.218%0.18328%0.276CS..Hα-helixtrans-63.3-37.5-178.4-68.2176.8000113I281 Y312 V349 L350 I409 L410I281-L413 HydrophobicContact CD1-CD1 4.2Å; Y312-L413 HydrophobicContact CD2-CD1 4.41Å; Y312-L413 HydrophobicContact CE1-CD1 4.25Å; Y312-L413 HydrophobicContact CE1-CD2 4.49Å; Y312-L413 HydrophobicContact CE2-CD1 3.81Å; V349-L413 HydrophobicContact CB-CD2 4.11Å; V349-L413 HydrophobicContact CG2-CD2 3.7Å; L350-L413 HydrophobicContact CB-CD2 3.88Å; L350-L413 HydrophobicContact CD2-CD2 4.42Å; L350-L413 HydrophobicContact CD2-CG 4.33Å; I409-L413 HydrophobicContact CG2-CD1 3.49Å; I409-L413 VanDerWaalsContact CG2-CD1 3.49Å; I409-L413 HydrophobicContact CG2-CG 4.18Å; I409-L413 WeakPolarHBondContact O-CG 3.27Å; I409-L413 PolarHBondContact O-N 3.15Å; L410-L413 PolarHBondContact O-N 2.87Å
414H97.8Very high98Very high137 Ų13755 Ų5563%0.63427%0.274SS*.THydrogen-bonded Turntrans-83.7-12-178.4-63.9170.5000113.6L410 V412L410-H414 VanDerWaalsContact O-CB 3.28Å; L410-H414 WeakPolarHBondContact O-CB 2.96Å; L410-H414 VanDerWaalsContact O-CG 3.29Å; L410-H414 PolarHBondContact O-N 2.79Å; V412-H414 VanDerWaalsContact C-N 3.35Å; V412-H414 PolarHBondContact O-N 3.06Å
415N98.2Very high97.8Very high67 Ų6752.7 Ų52.736%0.35826%0.259SS..  trans-108.492.3-178.9-174.2-18.7000110.9S411 V412 G417 Y418S411-N415 WeakPolarHBondContact O-CB 3.28Å; V412-N415 PolarHBondContact O-N 3.49Å; N415-G417 PolarHBondContact O-N 3.3Å; N415-G417 WeakPolarHBondContact OD1-CA 3.49Å; N415-G417 PolarHBondContact OD1-N 3.42Å; N415-Y418 HydrophobicContact CB-CD2 3.66Å; N415-Y418 HydrophobicContact CB-CE2 3.68Å; N415-Y418 WeakPolarHBondContact O-CD2 3.5Å; N415-Y418 PolarHBondContact O-N 2.71Å; N415-Y418 VanDerWaalsContact O-N 3.14Å
416S97.2Very high97.7Very high77 Ų7753.4 Ų53.454%0.53826%0.264SS..Hα-helixtrans-59.2-18.4177.2630000113.7Y418 K419 Q420S416-Y418 PolarHBondContact O-N 3.46Å; S416-K419 PolarHBondContact O-N 3.31Å; S416-K419 VanDerWaalsContact O-N 3.13Å; S416-Q420 WeakPolarHBondContact O-CG 3.22Å; S416-Q420 PolarHBondContact O-N 3.29Å
417G98.2Very high97.5Very high8 Ų853 Ų538%0.08227%0.272CS..Hα-helixtrans-59.4-31.917500000113.4N415 R421N415-G417 PolarHBondContact O-N 3.3Å; N415-G417 WeakPolarHBondContact OD1-CA 3.49Å; N415-G417 PolarHBondContact OD1-N 3.42Å; G417-R421 WeakPolarHBondContact O-CG 3.37Å; G417-R421 VanDerWaalsContact O-CZ 3.24Å; G417-R421 PolarHBondContact O-N 3.31Å; G417-R421 PolarHBondContact O-NE 3.45Å
418Y98.6Very high97.2Very high36 Ų3647.4 Ų47.414%0.14125%0.248CC..Hα-helixtrans-64.2-47.4173.7-65.7-62.1000111.3G390 G392 V393 S411 V412 N415 S416 Q420 R421 I422G390-Y418 WeakPolarHBondContact O-CD1 3.37Å; G392-Y418 VanDerWaalsContact CA-CD1 3.48Å; G392-Y418 WeakPolarHBondContact O-CE1 3.32Å; V393-Y418 HydrophobicContact CG1-CE2 4.26Å; V393-Y418 VanDerWaalsContact CG1-OH 3.27Å; V393-Y418 WeakPolarHBondContact CG1-OH 3.4Å; S411-Y418 WeakPolarHBondContact O-CE2 3.45Å; V412-Y418 HydrophobicContact CB-CD2 4.39Å; V412-Y418 HydrophobicContact CG1-CD2 4.11Å; V412-Y418 HydrophobicContact CG1-CG 4.48Å; N415-Y418 HydrophobicContact CB-CD2 3.66Å; N415-Y418 HydrophobicContact CB-CE2 3.68Å; N415-Y418 WeakPolarHBondContact O-CD2 3.5Å; N415-Y418 PolarHBondContact O-N 2.71Å; N415-Y418 VanDerWaalsContact O-N 3.14Å; S416-Y418 PolarHBondContact O-N 3.46Å; Y418-Q420 PolarHBondContact O-N 2.98Å; Y418-R421 VanDerWaalsContact CD1-NH2 3.29Å; Y418-R421 PolarHBondContact O-N 3.17Å; Y418-I422 WeakPolarHBondContact O-CG2 3.16Å; Y418-I422 PolarHBondContact O-N 2.82Å
419K98.2Very high96.9Very high89 Ų8947.3 Ų47.339%0.38725%0.246SC..Hα-helixtrans-61.1-44.6176.5-175.565.9177.6-171.80111.3A367 P369 S416 R421 I422 T423A367-K419 VanDerWaalsContact O-CD 3.25Å; A367-K419 WeakPolarHBondContact O-CD 3.39Å; A367-K419 WeakPolarHBondContact O-CE 3.3Å; A367-K419 PolarHBondContact O-NZ 3.34Å; P369-K419 HydrophobicContact CG-CB 4.04Å; P369-K419 HydrophobicContact CG-CD 4.15Å; S416-K419 PolarHBondContact O-N 3.31Å; S416-K419 VanDerWaalsContact O-N 3.13Å; K419-R421 PolarHBondContact O-N 3.38Å; K419-I422 HydrophobicContact CD-CG2 4.47Å; K419-I422 WeakPolarHBondContact O-CG2 3.4Å; K419-I422 PolarHBondContact O-N 3.11Å; K419-T423 WeakPolarHBondContact O-CB 3.22Å; K419-T423 PolarHBondContact O-N 3.25Å; K419-T423 PolarHBondContact O-OG1 3.37Å
420Q97.9Very high96.5Very high113 Ų11350.6 Ų50.653%0.52827%0.27SS..Hα-helixtrans-60.7-44.8178.4-68.5172.513.600112.5S416 Y418 K424S416-Q420 WeakPolarHBondContact O-CG 3.22Å; S416-Q420 PolarHBondContact O-N 3.29Å; Y418-Q420 PolarHBondContact O-N 2.98Å; Q420-K424 WeakPolarHBondContact O-CG 3.5Å; Q420-K424 PolarHBondContact O-N 3.4Å; Q420-K424 VanDerWaalsContact O-N 3.13Å
421R97Very high96.2Very high103 Ų10350.7 Ų50.739%0.38927%0.27SS..Hα-helixtrans-68.9-43.3-179.9-74.8-177-64.5-94.4-1112.3G390 G417 Y418 K419 K424 L425G390-R421 PolarHBondContact O-NE 3.4Å; G390-R421 PolarHBondContact O-NH2 2.9Å; G417-R421 WeakPolarHBondContact O-CG 3.37Å; G417-R421 VanDerWaalsContact O-CZ 3.24Å; G417-R421 PolarHBondContact O-N 3.31Å; G417-R421 PolarHBondContact O-NE 3.45Å; Y418-R421 VanDerWaalsContact CD1-NH2 3.29Å; Y418-R421 PolarHBondContact O-N 3.17Å; K419-R421 PolarHBondContact O-N 3.38Å; R421-K424 PolarHBondContact O-N 2.72Å; R421-L425 WeakPolarHBondContact O-CB 3.23Å; R421-L425 PolarHBondContact O-N 3.49Å
422I97.4Very high95.7Very high0 Ų051.6 Ų51.60%027%0.271CS..Hα-helixtrans-68.7-35.1178.3-159.3174.4000112.2A363 V364 A367 V368 P369 M370 L391 Y418 K419 L425 S426A363-I422 WeakPolarHBondContact O-CD1 3.43Å; V364-I422 HydrophobicContact CG2-CD1 4.26Å; V364-I422 HydrophobicContact CG2-CG1 4.33Å; A367-I422 HydrophobicContact CB-CG2 4.14Å; A367-I422 WeakPolarHBondContact O-CG2 3.35Å; V368-I422 WeakPolarHBondContact O-CD1 3.25Å; P369-I422 HydrophobicContact CG-CG2 4.25Å; M370-I422 HydrophobicContact CE-CD1 4.26Å; L391-I422 HydrophobicContact CB-CD1 4.33Å; L391-I422 HydrophobicContact CD1-CG1 4.48Å; L391-I422 HydrophobicContact CD2-CB 3.8Å; L391-I422 HydrophobicContact CD2-CG1 3.99Å; Y418-I422 WeakPolarHBondContact O-CG2 3.16Å; Y418-I422 PolarHBondContact O-N 2.82Å; K419-I422 HydrophobicContact CD-CG2 4.47Å; K419-I422 WeakPolarHBondContact O-CG2 3.4Å; K419-I422 PolarHBondContact O-N 3.11Å; I422-L425 PolarHBondContact O-N 3.35Å; I422-S426 VanDerWaalsContact O-CB 3.3Å; I422-S426 WeakPolarHBondContact O-CB 3.49Å; I422-S426 PolarHBondContact O-N 2.78Å
423T97.5Very high95.2Very high67 Ų6754.2 Ų54.241%0.41129%0.285SS..Hα-helixtrans-62-44.6172.4-62.90000111.4K419 S426 A427K419-T423 WeakPolarHBondContact O-CB 3.22Å; K419-T423 PolarHBondContact O-N 3.25Å; K419-T423 PolarHBondContact O-OG1 3.37Å; T423-S426 PolarHBondContact O-N 3.26Å; T423-A427 PolarHBondContact O-N 2.92Å
424K95.6Very high94.8Very high111 Ų11154.2 Ų54.248%0.48329%0.285SS..Hα-helixtrans-62.4-43.6175.4-73177.2-178-176.30111.9Q420 R421 A427 M428Q420-K424 WeakPolarHBondContact O-CG 3.5Å; Q420-K424 PolarHBondContact O-N 3.4Å; Q420-K424 VanDerWaalsContact O-N 3.13Å; R421-K424 PolarHBondContact O-N 2.72Å; K424-A427 PolarHBondContact O-N 2.83Å; K424-M428 WeakPolarHBondContact O-CG 3.35Å; K424-M428 PolarHBondContact O-N 2.98Å
425L94.9Very high94.3Very high2 Ų251.4 Ų51.41%0.0127%0.274CS..Hα-helixtrans-65.8-40.2177.9-175.359.5000112.3L241 V364 H389 L391 R421 I422 M428 L429L241-L425 HydrophobicContact CD1-CD2 3.96Å; V364-L425 HydrophobicContact CG1-CD2 4.13Å; V364-L425 HydrophobicContact CG1-CG 3.99Å; H389-L425 HydrophobicContact CB-CD2 4.16Å; L391-L425 HydrophobicContact CD1-CD2 3.81Å; L391-L425 HydrophobicContact CD2-CD2 3.92Å; L391-L425 HydrophobicContact CG-CD2 4.45Å; R421-L425 WeakPolarHBondContact O-CB 3.23Å; R421-L425 PolarHBondContact O-N 3.49Å; I422-L425 PolarHBondContact O-N 3.35Å; L425-M428 HydrophobicContact CB-CE 4.27Å; L425-M428 HydrophobicContact CD1-CE 3.78Å; L425-M428 PolarHBondContact O-N 2.75Å; L425-L429 HydrophobicContact CD1-CD1 4.05Å; L425-L429 HydrophobicContact CD1-CG 4.25Å; L425-L429 HydrophobicContact CG-CD1 3.89Å; L425-L429 WeakPolarHBondContact O-CB 3.48Å; L425-L429 WeakPolarHBondContact O-CG 3.08Å; L425-L429 PolarHBondContact O-N 2.63Å
426S95.2Very high93.8Very high14 Ų1450 Ų5010%0.09827%0.266CS..Hα-helixtrans-57.9-48.6173.3-177.80000111.7V364 C365 I422 T423 M428 L429 S430V364-S426 WeakPolarHBondContact O-CB 3.39Å; V364-S426 PolarHBondContact O-OG 3.08Å; V364-S426 VanDerWaalsContact O-OG 3.14Å; C365-S426 PolarHBondContact O-OG 3.16Å; I422-S426 VanDerWaalsContact O-CB 3.3Å; I422-S426 WeakPolarHBondContact O-CB 3.49Å; I422-S426 PolarHBondContact O-N 2.78Å; T423-S426 PolarHBondContact O-N 3.26Å; S426-M428 PolarHBondContact O-N 3.4Å; S426-L429 PolarHBondContact O-N 2.77Å; S426-S430 WeakPolarHBondContact O-CB 3.33Å; S426-S430 PolarHBondContact O-N 2.94Å; S426-S430 PolarHBondContact O-OG 3.23Å
427A95Very high93.5Very high47 Ų4747 Ų4739%0.38824%0.244SC..Hα-helixtrans-61.8-43.6179.100000111.8T423 K424 S430 D431T423-A427 PolarHBondContact O-N 2.92Å; K424-A427 PolarHBondContact O-N 2.83Å; A427-S430 PolarHBondContact O-N 3.24Å; A427-D431 WeakPolarHBondContact O-CB 3.35Å; A427-D431 PolarHBondContact O-N 2.92Å; A427-D431 VanDerWaalsContact O-N 3.17Å
428M92.4Very high93.1Very high4 Ų452.1 Ų52.12%0.0226%0.264CS..Hα-helixtrans-61-45.2175.3-73.2-175.8-59.200112K424 L425 S426 S430 D431 F701 H705 Q707K424-M428 WeakPolarHBondContact O-CG 3.35Å; K424-M428 PolarHBondContact O-N 2.98Å; L425-M428 HydrophobicContact CB-CE 4.27Å; L425-M428 HydrophobicContact CD1-CE 3.78Å; L425-M428 PolarHBondContact O-N 2.75Å; S426-M428 PolarHBondContact O-N 3.4Å; M428-S430 VanDerWaalsContact C-N 3.28Å; M428-S430 PolarHBondContact O-N 3.04Å; M428-D431 PolarHBondContact O-N 2.89Å; M428-F701 HydrophobicContact CB-CZ 4.14Å; M428-F701 HydrophobicContact CG-CZ 4.35Å; M428-F701 WeakPolarHBondContact O-CE2 3.49Å; M428-H705 HydrophobicContact CG-CB 3.69Å; M428-H705 WeakPolarHBondContact CG-ND1 3.22Å; M428-H705 HydrophobicContact SD-CB 4.08Å; M428-Q707 HydrophobicContact SD-CG 4.25Å
429L91.2Very high92.7Very high2 Ų252.9 Ų52.91%0.0127%0.268CS..Hα-helixtrans-73.8-16.9-178.5-76.6169.7000114S238 M240 L241 V364 L425 S426 N432S238-L429 WeakPolarHBondContact OG-CD2 3.32Å; M240-L429 HydrophobicContact CB-CD2 3.66Å; M240-L429 HydrophobicContact SD-CD2 4.35Å; L241-L429 HydrophobicContact CB-CD1 4.15Å; L241-L429 HydrophobicContact CB-CD2 4.33Å; L241-L429 HydrophobicContact CD1-CD1 4.28Å; V364-L429 HydrophobicContact CG1-CD1 3.54Å; L425-L429 HydrophobicContact CD1-CD1 4.05Å; L425-L429 HydrophobicContact CD1-CG 4.25Å; L425-L429 HydrophobicContact CG-CD1 3.89Å; L425-L429 WeakPolarHBondContact O-CB 3.48Å; L425-L429 WeakPolarHBondContact O-CG 3.08Å; L425-L429 PolarHBondContact O-N 2.63Å; S426-L429 PolarHBondContact O-N 2.77Å; L429-N432 PolarHBondContact O-ND2 3.1Å
430S90.9Very high92.4Very high70 Ų7048.6 Ų48.649%0.4925%0.249SC..Hα-helixtrans-92.1-19.8177.3-55.80000112.2S426 A427 M428 N432S426-S430 WeakPolarHBondContact O-CB 3.33Å; S426-S430 PolarHBondContact O-N 2.94Å; S426-S430 PolarHBondContact O-OG 3.23Å; A427-S430 PolarHBondContact O-N 3.24Å; M428-S430 VanDerWaalsContact C-N 3.28Å; M428-S430 PolarHBondContact O-N 3.04Å; S430-N432 PolarHBondContact O-N 2.78Å; S430-N432 VanDerWaalsContact O-N 3.16Å
431D91.8Very high92.2Very high32 Ų3243.3 Ų43.317%0.17123%0.225CC..  trans-8678.6178.3-173.60.1000110.2A427 M428 F697 F701 R704 H705A427-D431 WeakPolarHBondContact O-CB 3.35Å; A427-D431 PolarHBondContact O-N 2.92Å; A427-D431 VanDerWaalsContact O-N 3.17Å; M428-D431 PolarHBondContact O-N 2.89Å; D431-F697 WeakPolarHBondContact O-CZ 3.41Å; D431-F697 WeakPolarHBondContact OD1-CE2 3.4Å; D431-F701 HydrophobicContact CB-CD2 4.08Å; D431-F701 HydrophobicContact CB-CE2 3.93Å; D431-F701 WeakPolarHBondContact O-CD2 3.34Å; D431-F701 WeakPolarHBondContact O-CE2 3.49Å; D431-R704 VanDerWaalsContact CG-NH2 3.27Å; D431-R704 IonicContact OD1-CZ 3.78Å; D431-R704 IonicContact OD1-NE 3.46Å; D431-R704 IonicContact OD1-NH2 2.61Å; D431-R704 PolarHBondContact OD1-NH2 3.2Å; D431-R704 IonicContact OD2-CZ 2.87Å; D431-R704 VanDerWaalsContact OD2-CZ 3.26Å; D431-R704 IonicContact OD2-NE 2.78Å; D431-R704 PolarHBondContact OD2-NE 3.14Å; D431-R704 IonicContact OD2-NH2 2.76Å; D431-R704 PolarHBondContact OD2-NH2 3.22Å; D431-H705 IonicContact OD2-CD2 2.81Å; D431-H705 PolarHBondContact OD2-CD2 3.43Å; D431-H705 IonicContact OD2-NE2 2.8Å; D431-H705 PolarHBondContact OD2-NE2 3.15Å
432N88.3Confident92Very high65 Ų6539.8 Ų39.835%0.34821%0.212SC..  trans-109.9144.6179.9-59-66.3000111.1L429 S430 I434L429-N432 PolarHBondContact O-ND2 3.1Å; S430-N432 PolarHBondContact O-N 2.78Å; S430-N432 VanDerWaalsContact O-N 3.16Å; N432-I434 VanDerWaalsContact C-N 3.34Å
433L88.5Confident91.7Very high59 Ų5942.7 Ų42.731%0.30922%0.223SC..SBendtrans-69.4-32.7176.3179.356.1000112.8I689 K694 F697L433-I689 HydrophobicContact CD1-CG2 4.44Å; L433-I689 HydrophobicContact CD2-CD1 3.8Å; L433-I689 HydrophobicContact CD2-CG2 3.98Å; L433-I689 HydrophobicContact CG-CD1 3.83Å; L433-I689 HydrophobicContact CG-CG1 4.49Å; L433-I689 HydrophobicContact CG-CG2 4.32Å; L433-K694 HydrophobicContact CD2-CB 3.87Å; L433-K694 HydrophobicContact CD2-CG 3.89Å; L433-F697 HydrophobicContact CB-CD1 3.77Å; L433-F697 HydrophobicContact CB-CD2 4.12Å; L433-F697 HydrophobicContact CB-CE1 3.81Å; L433-F697 HydrophobicContact CB-CE2 4.14Å; L433-F697 HydrophobicContact CB-CG 3.93Å; L433-F697 HydrophobicContact CB-CZ 4Å; L433-F697 HydrophobicContact CD1-CB 3.83Å; L433-F697 HydrophobicContact CD1-CD1 4.41Å; L433-F697 HydrophobicContact CD1-CD2 3.85Å; L433-F697 HydrophobicContact CD1-CG 3.75Å; L433-F697 HydrophobicContact CD2-CB 4.27Å; L433-F697 HydrophobicContact CD2-CD1 4.21Å; L433-F697 HydrophobicContact CD2-CG 4.26Å; L433-F697 HydrophobicContact CG-CD1 4.36Å; L433-F697 HydrophobicContact CG-CG 4.2Å; L433-F697 VanDerWaalsContact N-CZ 3.35Å
434I88.4Confident91.5Very high35 Ų3539.5 Ų39.518%0.17920%0.204CC..SBendtrans-143.7147.8178.3-174.6166.8000108.6N432 E436 K438 K439 V688 I689N432-I434 VanDerWaalsContact C-N 3.34Å; I434-E436 PolarHBondContact O-N 2.77Å; I434-K438 HydrophobicContact CD1-CB 4.39Å; I434-K438 HydrophobicContact CG1-CB 4.23Å; I434-K439 HydrophobicContact CD1-CB 4.3Å; I434-K439 HydrophobicContact CG1-CB 4.45Å; I434-K439 HydrophobicContact CG2-CB 3.94Å; I434-K439 HydrophobicContact CG2-CD 4.08Å; I434-K439 HydrophobicContact CG2-CG 4.32Å; I434-V688 HydrophobicContact CD1-CG2 3.31Å; I434-I689 HydrophobicContact CB-CD1 4.01Å; I434-I689 HydrophobicContact CD1-CD1 4.41Å; I434-I689 HydrophobicContact CG2-CD1 3.85Å
435D88.2Confident91.4Very high78 Ų7834.6 Ų34.642%0.41718%0.183SC..  trans-59.7130.9169.1178.2-88.4000110.4T437 K438 K439D435-T437 VanDerWaalsContact C-N 3.27Å; D435-T437 PolarHBondContact O-N 3.44Å; D435-T437 VanDerWaalsContact OD1-CA 3.32Å; D435-T437 WeakPolarHBondContact OD1-CA 3.44Å; D435-T437 WeakPolarHBondContact OD1-CB 3.22Å; D435-T437 PolarHBondContact OD1-N 3.33Å; D435-T437 PolarHBondContact OD1-OG1 3.46Å; D435-K438 HydrophobicContact CB-CB 4.1Å; D435-K438 HydrophobicContact CB-CD 4.17Å; D435-K438 HydrophobicContact CB-CG 3.99Å; D435-K438 WeakPolarHBondContact O-CB 3.32Å; D435-K438 PolarHBondContact O-N 3.01Å; D435-K438 VanDerWaalsContact O-N 3.16Å; D435-K438 PolarHBondContact OD1-N 3.24Å; D435-K439 PolarHBondContact O-N 3.3Å
436E88Confident91.2Very high39 Ų3934.6 Ų34.618%0.18218%0.183CC..Hα-helixtrans-66.4-28.8-174.5-69.6-63.2135.200112.6S253 I254 D255 I434 K439 G440S253-E436 VanDerWaalsContact O-OE2 3.07Å; I254-E436 HydrophobicContact CG2-CB 4.39Å; D255-E436 HydrophobicContact CB-CG 4.41Å; I434-E436 PolarHBondContact O-N 2.77Å; E436-K439 IonicContact OE1-NZ 2.7Å; E436-K439 PolarHBondContact OE1-NZ 3.24Å; E436-K439 WeakPolarHBondContact OE2-CD 3.48Å; E436-K439 IonicContact OE2-NZ 3.15Å; E436-K439 PolarHBondContact OE2-NZ 3.44Å; E436-G440 PolarHBondContact O-N 3.45Å
437T90.1Very high91Very high13 Ų1335.2 Ų35.28%0.0818%0.184CC..Hα-helixtrans-68.7-44174.1-45.60000110.1P44 L45 E48 D435 K439 G440 S441P44-T437 HydrophobicContact CB-CG2 4.19Å; P44-T437 WeakPolarHBondContact O-CG2 3.5Å; L45-T437 HydrophobicContact CB-CG2 4.29Å; L45-T437 HydrophobicContact CD1-CG2 4.25Å; E48-T437 HydrophobicContact CB-CG2 3.75Å; E48-T437 HydrophobicContact CG-CG2 4.31Å; D435-T437 VanDerWaalsContact C-N 3.27Å; D435-T437 PolarHBondContact O-N 3.44Å; D435-T437 VanDerWaalsContact OD1-CA 3.32Å; D435-T437 WeakPolarHBondContact OD1-CA 3.44Å; D435-T437 WeakPolarHBondContact OD1-CB 3.22Å; D435-T437 PolarHBondContact OD1-N 3.33Å; D435-T437 PolarHBondContact OD1-OG1 3.46Å; T437-K439 PolarHBondContact O-N 3.31Å; T437-G440 PolarHBondContact O-N 2.71Å; T437-S441 PolarHBondContact O-N 2.95Å
438K91.2Very high90.8Very high115 Ų11534.2 Ų34.250%0.517%0.172SC..Hα-helixtrans-62-41.6174.4-69.7-168.7170.8-173.20112.7E48 I434 D435 S441 F442E48-K438 HydrophobicContact CG-CG 4.47Å; E48-K438 WeakPolarHBondContact OE1-CG 3.3Å; I434-K438 HydrophobicContact CD1-CB 4.39Å; I434-K438 HydrophobicContact CG1-CB 4.23Å; D435-K438 HydrophobicContact CB-CB 4.1Å; D435-K438 HydrophobicContact CB-CD 4.17Å; D435-K438 HydrophobicContact CB-CG 3.99Å; D435-K438 WeakPolarHBondContact O-CB 3.32Å; D435-K438 PolarHBondContact O-N 3.01Å; D435-K438 VanDerWaalsContact O-N 3.16Å; D435-K438 PolarHBondContact OD1-N 3.24Å; K438-S441 PolarHBondContact O-N 2.9Å; K438-F442 WeakPolarHBondContact O-CB 3.2Å; K438-F442 PolarHBondContact O-N 3.12Å
439K90.2Very high90.8Very high52 Ų5238.4 Ų38.423%0.22619%0.187CC..Hα-helixtrans-61.9-43.8174.4178.1-174.3165.9-161.20111.4I434 D435 E436 T437 F442 W443I434-K439 HydrophobicContact CD1-CB 4.3Å; I434-K439 HydrophobicContact CG1-CB 4.45Å; I434-K439 HydrophobicContact CG2-CB 3.94Å; I434-K439 HydrophobicContact CG2-CD 4.08Å; I434-K439 HydrophobicContact CG2-CG 4.32Å; D435-K439 PolarHBondContact O-N 3.3Å; E436-K439 IonicContact OE1-NZ 2.7Å; E436-K439 PolarHBondContact OE1-NZ 3.24Å; E436-K439 WeakPolarHBondContact OE2-CD 3.48Å; E436-K439 IonicContact OE2-NZ 3.15Å; E436-K439 PolarHBondContact OE2-NZ 3.44Å; T437-K439 PolarHBondContact O-N 3.31Å; K439-F442 PolarHBondContact O-N 2.84Å; K439-W443 PolarHBondContact O-N 2.92Å; K439-W443 VanDerWaalsContact O-N 3.11Å
440G91.5Very high90.7Very high0 Ų039.7 Ų39.70%019%0.193CC..Hα-helixtrans-59-49.3173.200000112.4E436 T437 F442 W443 I444E436-G440 PolarHBondContact O-N 3.45Å; T437-G440 PolarHBondContact O-N 2.71Å; G440-F442 VanDerWaalsContact C-N 3.32Å; G440-F442 PolarHBondContact O-N 2.88Å; G440-W443 PolarHBondContact O-N 3.24Å; G440-I444 VanDerWaalsContact O-CG1 3.3Å; G440-I444 WeakPolarHBondContact O-CG1 3.41Å; G440-I444 PolarHBondContact O-N 2.89Å
441S93.9Very high90.4Very high1 Ų140 Ų401%0.00719%0.194CC..Hα-helixtrans-60-42.3177.7-154.60000112L49 D52 T437 K438 W443 I444 S445L49-S441 VanDerWaalsContact CD2-OG 3.32Å; L49-S441 WeakPolarHBondContact CD2-OG 3.5Å; D52-S441 PolarHBondContact OD2-OG 3.15Å; T437-S441 PolarHBondContact O-N 2.95Å; K438-S441 PolarHBondContact O-N 2.9Å; S441-W443 PolarHBondContact O-N 3.11Å; S441-I444 PolarHBondContact O-N 3.33Å; S441-S445 VanDerWaalsContact O-CB 3.28Å; S441-S445 WeakPolarHBondContact O-CB 3.31Å; S441-S445 PolarHBondContact O-N 3.24Å; S441-S445 PolarHBondContact O-OG 3.49Å
442F92.8Very high89.8Confident29 Ų2943.6 Ų43.613%0.12721%0.21CC..Hα-helixtrans-58.1-50.3176.1173-92.6000112.1K438 K439 G440 S445 F446 D686 V688K438-F442 WeakPolarHBondContact O-CB 3.2Å; K438-F442 PolarHBondContact O-N 3.12Å; K439-F442 PolarHBondContact O-N 2.84Å; G440-F442 VanDerWaalsContact C-N 3.32Å; G440-F442 PolarHBondContact O-N 2.88Å; F442-S445 CarbonylContact O-C 3.54Å; F442-S445 PolarHBondContact O-N 3.22Å; F442-F446 HydrophobicContact CE1-CB 4.29Å; F442-F446 HydrophobicContact CE1-CD2 4.31Å; F442-F446 HydrophobicContact CZ-CD2 4.14Å; F442-F446 VanDerWaalsContact O-CB 3.25Å; F442-F446 WeakPolarHBondContact O-CB 3.23Å; F442-F446 PolarHBondContact O-N 2.8Å; F442-D686 WeakPolarHBondContact CZ-O 3.33Å; F442-V688 HydrophobicContact CB-CB 4.45Å; F442-V688 HydrophobicContact CB-CG2 4.18Å; F442-V688 HydrophobicContact CD1-CB 3.68Å; F442-V688 HydrophobicContact CD1-CG1 4.02Å; F442-V688 HydrophobicContact CD1-CG2 4.31Å; F442-V688 HydrophobicContact CD2-CB 3.66Å; F442-V688 HydrophobicContact CD2-CG2 3.89Å; F442-V688 HydrophobicContact CE1-CB 3.76Å; F442-V688 HydrophobicContact CE1-CG1 4.08Å; F442-V688 HydrophobicContact CE2-CB 3.73Å; F442-V688 HydrophobicContact CE2-CG2 4.39Å; F442-V688 HydrophobicContact CG-CB 3.63Å; F442-V688 HydrophobicContact CG-CG1 4.4Å; F442-V688 HydrophobicContact CG-CG2 3.84Å; F442-V688 HydrophobicContact CZ-CB 3.78Å
443W91.2Very high89.2Confident61 Ų6141 Ų4123%0.23120%0.197CC..Hα-helixtrans-67-38-178.2-76.4116.5000112.4Y232 F252 K439 G440 S441 F446 Y447Y232-W443 HydrophobicContact CE2-CB 4.26Å; Y232-W443 WeakPolarHBondContact CE2-O 3.36Å; F252-W443 HydrophobicContact CE1-CB 4.14Å; F252-W443 HydrophobicContact CE1-CG 4.28Å; F252-W443 HydrophobicContact CZ-CB 3.88Å; F252-W443 HydrophobicContact CZ-CG 4.29Å; K439-W443 PolarHBondContact O-N 2.92Å; K439-W443 VanDerWaalsContact O-N 3.11Å; G440-W443 PolarHBondContact O-N 3.24Å; S441-W443 PolarHBondContact O-N 3.11Å; W443-F446 HydrophobicContact CE3-CB 4.27Å; W443-F446 HydrophobicContact CE3-CD1 4.11Å; W443-F446 HydrophobicContact CE3-CG 4.14Å; W443-F446 HydrophobicContact CZ3-CD1 4.15Å; W443-F446 HydrophobicContact CZ3-CD2 4.5Å; W443-F446 HydrophobicContact CZ3-CE1 4.36Å; W443-F446 HydrophobicContact CZ3-CG 4.24Å; W443-F446 WeakPolarHBondContact O-CB 3.43Å; W443-F446 PolarHBondContact O-N 3.21Å; W443-Y447 PolarHBondContact O-N 3.46Å
444I93.2Very high88.2Confident0 Ų039 Ų390%019%0.188CC..Hα-helixtrans-59.8-51172.7-69172.1000110.1I27 L45 L49 L139 I141 I157 G440 S441 F446 Y447 L448I27-I444 HydrophobicContact CD1-CG2 4.33Å; L45-I444 HydrophobicContact CD1-CD1 4.16Å; L45-I444 HydrophobicContact CD2-CD1 3.8Å; L45-I444 HydrophobicContact CG-CD1 4.17Å; L49-I444 HydrophobicContact CD1-CD1 3.91Å; L49-I444 HydrophobicContact CD1-CG2 4.25Å; L49-I444 HydrophobicContact CD2-CB 4Å; L49-I444 HydrophobicContact CD2-CD1 4.41Å; L49-I444 HydrophobicContact CD2-CG2 3.61Å; L139-I444 HydrophobicContact CD2-CG2 3.6Å; I141-I444 HydrophobicContact CD1-CD1 3.92Å; I157-I444 HydrophobicContact CD1-CB 4.43Å; I157-I444 HydrophobicContact CD1-CD1 4.44Å; I157-I444 HydrophobicContact CD1-CG1 3.62Å; G440-I444 VanDerWaalsContact O-CG1 3.3Å; G440-I444 WeakPolarHBondContact O-CG1 3.41Å; G440-I444 PolarHBondContact O-N 2.89Å; S441-I444 PolarHBondContact O-N 3.33Å; I444-F446 VanDerWaalsContact C-N 3.3Å; I444-F446 PolarHBondContact O-N 3Å; I444-Y447 PolarHBondContact O-N 3.48Å; I444-L448 HydrophobicContact CG2-CD1 4.18Å; I444-L448 WeakPolarHBondContact O-CG 3.44Å; I444-L448 PolarHBondContact O-N 3.41Å
445S92.5Very high86.8Confident8 Ų840.8 Ų40.86%0.05620%0.204CC..Hα-helixtrans-65.4-32.8178.3-68.30000112.3D52 H54 S441 F442 L448 R449D52-S445 PolarHBondContact OD2-OG 3.11Å; H54-S445 PolarHBondContact NE2-OG 2.83Å; S441-S445 VanDerWaalsContact O-CB 3.28Å; S441-S445 WeakPolarHBondContact O-CB 3.31Å; S441-S445 PolarHBondContact O-N 3.24Å; S441-S445 PolarHBondContact O-OG 3.49Å; F442-S445 CarbonylContact O-C 3.54Å; F442-S445 PolarHBondContact O-N 3.22Å; S445-L448 PolarHBondContact O-N 3.49Å; S445-R449 VanDerWaalsContact CB-NH1 3.27Å; S445-R449 WeakPolarHBondContact O-CG 3.49Å; S445-R449 PolarHBondContact O-N 3.3Å; S445-R449 PolarHBondContact O-NH1 3.49Å
446F91.2Very high85Confident2 Ų241.3 Ų41.31%0.00920%0.203CC..Hα-helixtrans-61.4-47.9173.6176.8-83000110.6F442 W443 I444 L448 R449 H450 M495 M683 D686F442-F446 HydrophobicContact CE1-CB 4.29Å; F442-F446 HydrophobicContact CE1-CD2 4.31Å; F442-F446 HydrophobicContact CZ-CD2 4.14Å; F442-F446 VanDerWaalsContact O-CB 3.25Å; F442-F446 WeakPolarHBondContact O-CB 3.23Å; F442-F446 PolarHBondContact O-N 2.8Å; W443-F446 HydrophobicContact CE3-CB 4.27Å; W443-F446 HydrophobicContact CE3-CD1 4.11Å; W443-F446 HydrophobicContact CE3-CG 4.14Å; W443-F446 HydrophobicContact CZ3-CD1 4.15Å; W443-F446 HydrophobicContact CZ3-CD2 4.5Å; W443-F446 HydrophobicContact CZ3-CE1 4.36Å; W443-F446 HydrophobicContact CZ3-CG 4.24Å; W443-F446 WeakPolarHBondContact O-CB 3.43Å; W443-F446 PolarHBondContact O-N 3.21Å; I444-F446 VanDerWaalsContact C-N 3.3Å; I444-F446 PolarHBondContact O-N 3Å; F446-L448 VanDerWaalsContact C-N 3.32Å; F446-L448 PolarHBondContact O-N 2.8Å; F446-R449 PolarHBondContact O-N 2.96Å; F446-H450 AromaticContact CD2-CD2 3.87Å; F446-H450 HydrophobicContact CE1-CB 4.36Å; F446-H450 AromaticContact CE2-CD2 3.74Å; F446-H450 AromaticContact CZ-CD2 3.88Å; F446-H450 WeakPolarHBondContact O-CB 3.45Å; F446-H450 PolarHBondContact O-CD2 3.27Å; F446-H450 PolarHBondContact O-N 3.28Å; F446-M495 HydrophobicContact CE1-CE 4.49Å; F446-M495 HydrophobicContact CE1-SD 4.34Å; F446-M495 HydrophobicContact CE2-CE 4.19Å; F446-M495 HydrophobicContact CZ-CE 3.63Å; F446-M495 HydrophobicContact CZ-SD 3.75Å; F446-M683 HydrophobicContact CE2-CB 4.46Å; F446-M683 HydrophobicContact CZ-CB 3.92Å; F446-M683 HydrophobicContact CZ-CG 4.08Å; F446-D686 HydrophobicContact CD2-CB 4.11Å; F446-D686 HydrophobicContact CE2-CB 3.91Å; F446-D686 WeakPolarHBondContact CE2-O 3.35Å
447Y90.9Very high83.1Confident27 Ų2740.6 Ų40.611%0.10620%0.201CC..Hα-helixtrans-59.4-43.7173.9170.8-103000111.8L139 A155 V231 W443 I444 R449 H450 P451 A454L139-Y447 HydrophobicContact CD1-CD1 4.25Å; L139-Y447 HydrophobicContact CD1-CE1 4.1Å; A155-Y447 HydrophobicContact CB-CE1 3.66Å; A155-Y447 WeakPolarHBondContact CB-OH 3.39Å; V231-Y447 HydrophobicContact CB-CD2 4.32Å; V231-Y447 HydrophobicContact CB-CE2 4.3Å; V231-Y447 HydrophobicContact CG1-CD1 4.06Å; V231-Y447 HydrophobicContact CG1-CD2 3.26Å; V231-Y447 HydrophobicContact CG1-CE1 4.43Å; V231-Y447 HydrophobicContact CG1-CE2 3.68Å; V231-Y447 HydrophobicContact CG1-CG 3.48Å; V231-Y447 VanDerWaalsContact CG1-CG 3.48Å; V231-Y447 HydrophobicContact CG2-CD1 4.43Å; V231-Y447 HydrophobicContact CG2-CD2 4.07Å; V231-Y447 HydrophobicContact CG2-CE1 4Å; V231-Y447 HydrophobicContact CG2-CE2 3.57Å; V231-Y447 HydrophobicContact CG2-CG 4.47Å; W443-Y447 PolarHBondContact O-N 3.46Å; I444-Y447 PolarHBondContact O-N 3.48Å; Y447-R449 VanDerWaalsContact C-N 3.26Å; Y447-R449 PolarHBondContact O-N 3.45Å; Y447-H450 CarbonylContact O-C 3.52Å; Y447-H450 PolarHBondContact O-N 2.81Å; Y447-P451 HydrophobicContact CE2-CB 4.42Å; Y447-P451 VanDerWaalsContact CE2-O 3.29Å; Y447-P451 WeakPolarHBondContact CE2-O 3.23Å; Y447-P451 VanDerWaalsContact O-CA 3.23Å; Y447-P451 WeakPolarHBondContact O-CA 3.46Å; Y447-A454 HydrophobicContact CD2-CB 4.23Å; Y447-A454 HydrophobicContact CE2-CB 3.87Å
448L91.5Very high80.9Confident26 Ų2643.4 Ų43.414%0.13622%0.218CC..Hα-helixtrans-63.9-30.6178.7-67.5171.5000112.8K25 I27 D138 L139 I444 S445 F446K25-L448 HydrophobicContact CB-CD1 4.01Å; K25-L448 HydrophobicContact CB-CD2 4.36Å; K25-L448 HydrophobicContact CG-CB 4.4Å; K25-L448 HydrophobicContact CG-CD1 4.04Å; K25-L448 HydrophobicContact CG-CD2 4.19Å; K25-L448 HydrophobicContact CG-CG 4.45Å; I27-L448 HydrophobicContact CD1-CD1 3.97Å; D138-L448 HydrophobicContact CB-CD2 4.33Å; L139-L448 HydrophobicContact CB-CD2 4.18Å; L139-L448 HydrophobicContact CD2-CD2 4.49Å; I444-L448 HydrophobicContact CG2-CD1 4.18Å; I444-L448 WeakPolarHBondContact O-CG 3.44Å; I444-L448 PolarHBondContact O-N 3.41Å; S445-L448 PolarHBondContact O-N 3.49Å; F446-L448 VanDerWaalsContact C-N 3.32Å; F446-L448 PolarHBondContact O-N 2.8Å
449R90.8Very high78.5Confident93 Ų9339.3 Ų39.335%0.35120%0.203SC..Hα-helixtrans-77-32.5171.6-69.8-173.3-58.8-89.96.4112.4S445 F446 Y447 D686S445-R449 VanDerWaalsContact CB-NH1 3.27Å; S445-R449 WeakPolarHBondContact O-CG 3.49Å; S445-R449 PolarHBondContact O-N 3.3Å; S445-R449 PolarHBondContact O-NH1 3.49Å; F446-R449 PolarHBondContact O-N 2.96Å; Y447-R449 VanDerWaalsContact C-N 3.26Å; Y447-R449 PolarHBondContact O-N 3.45Å; R449-D686 IonicContact CZ-OD1 2.67Å; R449-D686 IonicContact CZ-OD2 2.85Å; R449-D686 IonicContact NE-OD1 2.73Å; R449-D686 IonicContact NE-OD2 2.81Å; R449-D686 PolarHBondContact NE-OD2 2.88Å; R449-D686 IonicContact NH2-OD1 2.59Å; R449-D686 PolarHBondContact NH2-OD1 3.37Å; R449-D686 IonicContact NH2-OD2 3.44Å; R449-D686 PolarHBondContact NH2-OD2 3.31Å
450H90.1Very high76Confident28 Ų2840.8 Ų40.813%0.1322%0.217CC..  trans-128.966.8-174.7-56.2-73.3000111.6F446 Y447 Q452 S453 M683 D686F446-H450 AromaticContact CD2-CD2 3.87Å; F446-H450 HydrophobicContact CE1-CB 4.36Å; F446-H450 AromaticContact CE2-CD2 3.74Å; F446-H450 AromaticContact CZ-CD2 3.88Å; F446-H450 WeakPolarHBondContact O-CB 3.45Å; F446-H450 PolarHBondContact O-CD2 3.27Å; F446-H450 PolarHBondContact O-N 3.28Å; Y447-H450 CarbonylContact O-C 3.52Å; Y447-H450 PolarHBondContact O-N 2.81Å; H450-Q452 PolarHBondContact O-N 2.85Å; H450-S453 WeakPolarHBondContact O-CB 3.15Å; H450-S453 PolarHBondContact O-N 3.31Å; H450-S453 PolarHBondContact O-OG 2.85Å; H450-M683 HydrophobicContact CB-CE 4.14Å; H450-M683 HydrophobicContact CB-CG 3.95Å; H450-M683 HydrophobicContact CB-SD 4.37Å; H450-D686 IonicContact CD2-OD2 3.66Å; H450-D686 PolarHBondContact CD2-OD2 3.05Å; H450-D686 IonicContact NE2-OD2 3.78Å; H450-D686 PolarHBondContact NE2-OD2 3.26Å
451P84.9Confident73.4Confident78 Ų7845.7 Ų45.751%0.50624%0.242SC..THydrogen-bonded Turntrans-64.7-18.4-17122.9-34.3000114.1Y447 S453Y447-P451 HydrophobicContact CE2-CB 4.42Å; Y447-P451 VanDerWaalsContact CE2-O 3.29Å; Y447-P451 WeakPolarHBondContact CE2-O 3.23Å; Y447-P451 VanDerWaalsContact O-CA 3.23Å; Y447-P451 WeakPolarHBondContact O-CA 3.46Å; P451-S453 VanDerWaalsContact C-N 3.35Å
452Q78Confident70.6Confident107 Ų10750.2 Ų50.250%0.527%0.265SS..THydrogen-bonded Turntrans-83.4-9.1174.5-64.7-175.6-13.200113.5H450 A454 S455H450-Q452 PolarHBondContact O-N 2.85Å; Q452-A454 PolarHBondContact O-N 3.24Å; Q452-S455 WeakPolarHBondContact O-CB 2.99Å; Q452-S455 PolarHBondContact O-N 3.33Å; Q452-S455 PolarHBondContact O-OG 3.36Å
453S75.5Confident67.5Low11 Ų1156 Ų568%0.07729%0.293CS..G310 helixtrans-56-35.8177.558.30000111.9H450 P451 S455 I457H450-S453 WeakPolarHBondContact O-CB 3.15Å; H450-S453 PolarHBondContact O-N 3.31Å; H450-S453 PolarHBondContact O-OG 2.85Å; P451-S453 VanDerWaalsContact C-N 3.35Å; S453-S455 VanDerWaalsContact C-N 3.32Å; S453-S455 PolarHBondContact O-N 3.47Å; S453-I457 WeakPolarHBondContact O-CG1 3.35Å
454A67.4Low64.4Low16 Ų1659 Ų5913%0.13232%0.32CS..G310 helixtrans-72.4-17.5178.900000114.9V231 Y447 Q452 H456 I457V231-A454 HydrophobicContact CB-CB 4.43Å; V231-A454 HydrophobicContact CG1-CB 4.12Å; V231-A454 HydrophobicContact CG2-CB 4.21Å; Y447-A454 HydrophobicContact CD2-CB 4.23Å; Y447-A454 HydrophobicContact CE2-CB 3.87Å; Q452-A454 PolarHBondContact O-N 3.24Å; A454-H456 PolarHBondContact O-N 3.38Å; A454-I457 WeakPolarHBondContact O-CB 3.46Å; A454-I457 PolarHBondContact O-N 3.13Å
455S59.5Low61.4Low72 Ų7264 Ų6450%0.50335%0.346SS..G310 helixtrans-67.1-20.2-174.864.70000114.1Q452 S453Q452-S455 WeakPolarHBondContact O-CB 2.99Å; Q452-S455 PolarHBondContact O-N 3.33Å; Q452-S455 PolarHBondContact O-OG 3.36Å; S453-S455 VanDerWaalsContact C-N 3.32Å; S453-S455 PolarHBondContact O-N 3.47Å
456H50.3Low58.1Low89 Ų8975.2 Ų75.241%0.41239%0.387SS..G310 helixtrans-98.6-4.7173.6-58.1-61.8000112.7A454A454-H456 PolarHBondContact O-N 3.38Å
457I48.4Very low55.2Low25 Ų2581.8 Ų81.813%0.12842%0.421CS..THydrogen-bonded Turntrans-86.2-19.8-172.7-62.1-170.3000112.4Y232 N250 S453 A454 T459 I499Y232-I457 HydrophobicContact CE1-CD1 4.12Å; N250-I457 HydrophobicContact CB-CG2 3.3Å; N250-I457 VanDerWaalsContact CG-CG2 3.48Å; N250-I457 WeakPolarHBondContact ND2-CG2 3.28Å; S453-I457 WeakPolarHBondContact O-CG1 3.35Å; A454-I457 WeakPolarHBondContact O-CB 3.46Å; A454-I457 PolarHBondContact O-N 3.13Å; I457-T459 PolarHBondContact O-N 3.32Å; I457-T459 PolarHBondContact O-OG1 2.91Å; I457-I499 VanDerWaalsContact CA-CD1 3.46Å; I457-I499 HydrophobicContact CB-CD1 3.72Å; I457-I499 HydrophobicContact CG1-CD1 3.83Å; I457-I499 HydrophobicContact CG2-CD1 3.53Å
458T44.9Very low52.2Low71 Ų7188.1 Ų88.144%0.43646%0.455SS..SBendtrans-58.1107.1175.654.40000108.8P460T458-P460 WeakPolarHBondContact O-CD 3.43Å
459T39.7Very low49.2Very low30 Ų3097.3 Ų97.318%0.18449%0.488CS..  trans-64.6116-166.6-45.40000109.3I457 M461I457-T459 PolarHBondContact O-N 3.32Å; I457-T459 PolarHBondContact O-OG1 2.91Å; T459-M461 HydrophobicContact CG2-CB 3.69Å; T459-M461 HydrophobicContact CG2-CG 3.83Å; T459-M461 PolarHBondContact O-N 3.25Å
460P38.3Very low46.2Very low82 Ų8297 Ų9753%0.53251%0.505SS..G310 helixtrans-68.6-1.6176.1-1731.4000113.1T458 L462 Q463T458-P460 WeakPolarHBondContact O-CD 3.43Å; P460-L462 PolarHBondContact O-N 2.86Å; P460-Q463 PolarHBondContact O-N 3.16Å
461M36.1Very low43.3Very low104 Ų104100.1 Ų100.151%0.51253%0.526SS..G310 helixtrans-64.7-5.6179-73-143.1132.500114.4T459 Q463 P501T459-M461 HydrophobicContact CG2-CB 3.69Å; T459-M461 HydrophobicContact CG2-CG 3.83Å; T459-M461 PolarHBondContact O-N 3.25Å; M461-Q463 VanDerWaalsContact C-N 3.29Å; M461-P501 HydrophobicContact SD-CG 4.28Å
462L35.6Very low40.9Very low96 Ų96101.8 Ų101.850%0.50354%0.54SS..G310 helixtrans-80.9-4.8175.6-67168.6000114.2L171 T228 P460L171-L462 HydrophobicContact CD2-CD2 4.15Å; T228-L462 HydrophobicContact CG2-CD1 3.36Å; P460-L462 PolarHBondContact O-N 2.86Å
463Q26.9Very low38.8Very low150 Ų150101.6 Ų101.670%0.70154%0.542SS*.SBendtrans-83.5125.3156.3-69.4-166.5-15.700107.6P460 M461 I465P460-Q463 PolarHBondContact O-N 3.16Å; M461-Q463 VanDerWaalsContact C-N 3.29Å; Q463-I465 PolarHBondContact O-N 3.43Å
464P27.7Very low36.7Very low125 Ų125104.4 Ų104.481%0.81256%0.56SS**  trans-6291.7175.723.7-30.4000108.5R466P464-R466 PolarHBondContact O-N 2.86Å
465I29.8Very low35.4Very low104 Ų104108.6 Ų108.653%0.53359%0.586SS.*  trans-68.9102.9174-73174.1000105.6Q463 I467Q463-I465 PolarHBondContact O-N 3.43Å; I465-I467 HydrophobicContact CG2-CB 4.03Å; I465-I467 HydrophobicContact CG2-CD1 3.32Å; I465-I467 HydrophobicContact CG2-CG1 3.33Å; I465-I467 PolarHBondContact O-N 3.34Å
466R23.7Very low34.4Very low243 Ų243109.2 Ų109.292%0.91759%0.59SS**  trans-6170.9160-71179.1171.4176.9-2.7109.2P464 L468P464-R466 PolarHBondContact O-N 2.86Å; R466-L468 VanDerWaalsContact C-N 3.34Å; R466-L468 PolarHBondContact O-N 3.43Å
467I29.9Very low34Very low141 Ų141107.1 Ų107.172%0.72358%0.583SS**  trans-92.782.7158.6-71.5163.8000106.9I465 R469I465-I467 HydrophobicContact CG2-CB 4.03Å; I465-I467 HydrophobicContact CG2-CD1 3.32Å; I465-I467 HydrophobicContact CG2-CG1 3.33Å; I465-I467 PolarHBondContact O-N 3.34Å; I467-R469 PolarHBondContact O-N 3.45Å
468L27.9Very low33.5Very low159 Ų159111.5 Ų111.583%0.83260%0.603SS**  trans-64.8108150.3-93149.9000107.3R466R466-L468 VanDerWaalsContact C-N 3.34Å; R466-L468 PolarHBondContact O-N 3.43Å
469R27.2Very low33Very low219 Ų219114.1 Ų114.183%0.82661%0.614SS**  trans-162.588.8143.5-105.8170.1-162.5-162.64.8108.7I467 V471I467-R469 PolarHBondContact O-N 3.45Å; R469-V471 HydrophobicContact CB-CG2 4.42Å; R469-V471 HydrophobicContact CG-CG2 4.48Å; R469-V471 PolarHBondContact O-N 2.89Å
470A27.6Very low32.9Very low86 Ų86116 Ų11671%0.71163%0.626SS**  trans-6787.115300000107.1
471V30.4Very low32.8Very low94 Ų94117.2 Ų117.257%0.5763%0.626SS**  trans-90.3108.8156.5179.30000104.5R469 L473R469-V471 HydrophobicContact CB-CG2 4.42Å; R469-V471 HydrophobicContact CG-CG2 4.48Å; R469-V471 PolarHBondContact O-N 2.89Å; V471-L473 VanDerWaalsContact C-N 3.29Å; V471-L473 HydrophobicContact CG1-CD2 4.32Å; V471-L473 PolarHBondContact O-N 3.19Å
472S34.5Very low32.9Very low114 Ų114114.3 Ų114.380%0.79762%0.616SS**  trans-56.4100.6159.446.20000106.6
473L32.8Very low32.9Very low103 Ų103113.4 Ų113.454%0.53961%0.614SS.*  trans-68.4138.2179.3-73.2164.3000108.5V471 V477V471-L473 VanDerWaalsContact C-N 3.29Å; V471-L473 HydrophobicContact CG1-CD2 4.32Å; V471-L473 PolarHBondContact O-N 3.19Å; L473-V477 HydrophobicContact CB-CB 4.04Å; L473-V477 HydrophobicContact CB-CG1 4.14Å; L473-V477 HydrophobicContact CD1-CG1 3.88Å; L473-V477 HydrophobicContact CD2-CG1 4.14Å; L473-V477 HydrophobicContact CD2-CG2 4.47Å; L473-V477 HydrophobicContact CG-CG1 4.27Å
474P32.4Very low33.9Very low70 Ų70108.5 Ų108.546%0.45559%0.592SS.*  trans-60.2157.3177.8-11.919.5000112S476 V477 E478P474-S476 PolarHBondContact O-N 2.91Å; P474-V477 PolarHBondContact O-N 2.77Å; P474-E478 PolarHBondContact O-N 2.9Å
475P40.3Very low34.4Very low103 Ų103104.7 Ų104.767%0.66957%0.565SS**Hα-helixtrans-54.1-27.6-178-25.733.1000114.8V477 E478 L479P475-V477 VanDerWaalsContact C-N 3.28Å; P475-V477 PolarHBondContact O-N 2.9Å; P475-E478 WeakPolarHBondContact O-CB 3.34Å; P475-E478 PolarHBondContact O-N 3.47Å; P475-L479 PolarHBondContact O-N 3.35Å
476S38.9Very low34.9Very low86 Ų86103.8 Ų103.860%0.60156%0.559SS**Hα-helixtrans-64.9-29.3175.853.60000113.3P474 L479P474-S476 PolarHBondContact O-N 2.91Å; S476-L479 WeakPolarHBondContact O-CB 3.03Å
477V40.8Very low35.5Very low44 Ų4498.5 Ų98.527%0.26754%0.54SS..Hα-helixtrans-84-28.1175.3-1760000111.3L473 P474 P475 L479 T480 M481L473-V477 HydrophobicContact CB-CB 4.04Å; L473-V477 HydrophobicContact CB-CG1 4.14Å; L473-V477 HydrophobicContact CD1-CG1 3.88Å; L473-V477 HydrophobicContact CD2-CG1 4.14Å; L473-V477 HydrophobicContact CD2-CG2 4.47Å; L473-V477 HydrophobicContact CG-CG1 4.27Å; P474-V477 PolarHBondContact O-N 2.77Å; P475-V477 VanDerWaalsContact C-N 3.28Å; P475-V477 PolarHBondContact O-N 2.9Å; V477-L479 PolarHBondContact O-N 2.9Å; V477-T480 VanDerWaalsContact CA-OG1 3.24Å; V477-T480 WeakPolarHBondContact CA-OG1 3.44Å; V477-T480 WeakPolarHBondContact CG1-OG1 3.27Å; V477-T480 CarbonylContact O-C 3.59Å; V477-T480 WeakPolarHBondContact O-CA 3.41Å; V477-T480 PolarHBondContact O-N 2.85Å; V477-T480 PolarHBondContact O-OG1 3.21Å; V477-M481 PolarHBondContact O-N 2.98Å
478E37.3Very low36Very low117 Ų11795 Ų9555%0.54753%0.528SS..Hα-helixtrans-60.2-32.7169.4-152.2172.6-162.800110.9P474 P475 M481 S482P474-E478 PolarHBondContact O-N 2.9Å; P475-E478 WeakPolarHBondContact O-CB 3.34Å; P475-E478 PolarHBondContact O-N 3.47Å; E478-M481 PolarHBondContact O-N 3.34Å; E478-S482 WeakPolarHBondContact O-CB 3.22Å; E478-S482 PolarHBondContact O-N 2.92Å; E478-S482 PolarHBondContact O-OG 3.48Å
479L35.6Very low36.3Very low126 Ų12693.9 Ų93.966%0.6652%0.522SS*.Hα-helixtrans-65-41169.7-141.184.5000112.4P475 S476 V477 S482 T483P475-L479 PolarHBondContact O-N 3.35Å; S476-L479 WeakPolarHBondContact O-CB 3.03Å; V477-L479 PolarHBondContact O-N 2.9Å; L479-S482 CarbonylContact O-C 3.54Å; L479-S482 PolarHBondContact O-N 3.17Å; L479-T483 PolarHBondContact O-N 3.14Å; L479-T483 PolarHBondContact O-OG1 2.83Å
480T37.1Very low37.2Very low71 Ų7184.9 Ų84.944%0.43650%0.497SS..Hα-helixtrans-71.3-25.9176.756.50000114.1V477 T483 M486V477-T480 VanDerWaalsContact CA-OG1 3.24Å; V477-T480 WeakPolarHBondContact CA-OG1 3.44Å; V477-T480 WeakPolarHBondContact CG1-OG1 3.27Å; V477-T480 CarbonylContact O-C 3.59Å; V477-T480 WeakPolarHBondContact O-CA 3.41Å; V477-T480 PolarHBondContact O-N 2.85Å; V477-T480 PolarHBondContact O-OG1 3.21Å; T480-T483 VanDerWaalsContact C-OG1 3.25Å; T480-T483 WeakPolarHBondContact CA-OG1 3.32Å; T480-T483 PolarHBondContact O-OG1 3.39Å; T480-M486 WeakPolarHBondContact O-CE 3.32Å
481M35.7Very low38.8Very low107 Ų10781.8 Ų81.853%0.52747%0.47SS..Hα-helixtrans-81.7-25.5169.3-76.1-72.2-159.400112V477 E478 M486V477-M481 PolarHBondContact O-N 2.98Å; E478-M481 PolarHBondContact O-N 3.34Å; M481-M486 HydrophobicContact CE-CE 4.47Å; M481-M486 HydrophobicContact CG-CE 4.27Å; M481-M486 HydrophobicContact SD-CE 3.47Å; M481-M486 WeakPolarHBondContact SD-CE 3.28Å
482S37.8Very low40.8Very low43 Ų4377.7 Ų77.730%0.30145%0.445SS..Hα-helixtrans-78.9-18.6175.2-63.60000113.5E478 L479 L484 R713E478-S482 WeakPolarHBondContact O-CB 3.22Å; E478-S482 PolarHBondContact O-N 2.92Å; E478-S482 PolarHBondContact O-OG 3.48Å; L479-S482 CarbonylContact O-C 3.54Å; L479-S482 PolarHBondContact O-N 3.17Å; S482-L484 PolarHBondContact O-N 2.95Å; S482-R713 PolarHBondContact O-NH2 3Å
483T36.2Very low42.6Very low76 Ų7672.4 Ų72.447%0.46641%0.408SS..SBendtrans-61.6123.5174.628.50000110.4L479 T480 L485L479-T483 PolarHBondContact O-N 3.14Å; L479-T483 PolarHBondContact O-OG1 2.83Å; T480-T483 VanDerWaalsContact C-OG1 3.25Å; T480-T483 WeakPolarHBondContact CA-OG1 3.32Å; T480-T483 PolarHBondContact O-OG1 3.39Å; T483-L485 PolarHBondContact O-N 3.34Å
484L47.5Very low44.4Very low48 Ų4869.2 Ų69.225%0.25139%0.393SS..SBendtrans-60-16.1-159.5-105.780.4000116.3S482 Y702S482-L484 PolarHBondContact O-N 2.95Å; L484-Y702 HydrophobicContact CD2-CD2 4.03Å; L484-Y702 HydrophobicContact CD2-CE2 3.13Å; L484-Y702 WeakPolarHBondContact CD2-OH 3.25Å
485L39.5Very low46.6Very low45 Ų4568.5 Ų68.524%0.23638%0.384CS..SBendtrans-147.7122.8165.3-76106.5000106.3T483 Y487 N505 F507T483-L485 PolarHBondContact O-N 3.34Å; L485-Y487 PolarHBondContact O-N 3.33Å; L485-Y487 VanDerWaalsContact O-N 3.15Å; L485-N505 WeakPolarHBondContact CA-O 3.46Å; L485-F507 HydrophobicContact CD2-CD1 4.18Å; L485-F507 HydrophobicContact CD2-CE1 3.25Å; L485-F507 HydrophobicContact CD2-CZ 3.79Å
486M39.9Very low48.4Very low84 Ų8463.6 Ų63.641%0.41435%0.352SS..  trans-79104.2174.9-162.4179.8-71.200108.1T480 M481 S488 T506T480-M486 WeakPolarHBondContact O-CE 3.32Å; M481-M486 HydrophobicContact CE-CE 4.47Å; M481-M486 HydrophobicContact CG-CE 4.27Å; M481-M486 HydrophobicContact SD-CE 3.47Å; M481-M486 WeakPolarHBondContact SD-CE 3.28Å; M486-S488 PolarHBondContact O-N 3.46Å; M486-T506 HydrophobicContact CB-CG2 4.1Å
487Y36.1Very low50.4Low133 Ų13360.9 Ų60.952%0.52233%0.331SS..  trans-83.996.7178.7-167-112.4000109L485 I489 L509L485-Y487 PolarHBondContact O-N 3.33Å; L485-Y487 VanDerWaalsContact O-N 3.15Å; Y487-I489 HydrophobicContact CD1-CD1 3.6Å; Y487-I489 HydrophobicContact CD1-CG1 3.17Å; Y487-I489 HydrophobicContact CE1-CB 4.43Å; Y487-I489 HydrophobicContact CE1-CD1 3.33Å; Y487-I489 HydrophobicContact CE1-CG1 3.04Å; Y487-I489 HydrophobicContact CG-CG1 4.31Å; Y487-I489 PolarHBondContact O-N 3.41Å; Y487-L509 HydrophobicContact CD2-CD1 4.16Å; Y487-L509 HydrophobicContact CE2-CD1 3.28Å; Y487-L509 HydrophobicContact CE2-CG 4.32Å
488S40.9Very low51.9Low66 Ų6662.4 Ų62.446%0.46234%0.337SS..  trans-87.588.9171.9-1700000109.6M486 G490 S491M486-S488 PolarHBondContact O-N 3.46Å; S488-G490 PolarHBondContact O-N 3.11Å; S488-S491 PolarHBondContact O-OG 2.98Å
489I34.1Very low53.5Low136 Ų13657.6 Ų57.670%0.69732%0.315SS*.THydrogen-bonded Turntrans-63.8124170.2-54.9176.8000108Y487Y487-I489 HydrophobicContact CD1-CD1 3.6Å; Y487-I489 HydrophobicContact CD1-CG1 3.17Å; Y487-I489 HydrophobicContact CE1-CB 4.43Å; Y487-I489 HydrophobicContact CE1-CD1 3.33Å; Y487-I489 HydrophobicContact CE1-CG1 3.04Å; Y487-I489 HydrophobicContact CG-CG1 4.31Å; Y487-I489 PolarHBondContact O-N 3.41Å
490G46.8Very low55.1Low30 Ų3055.7 Ų55.731%0.30931%0.305SS..THydrogen-bonded Turntrans81.325.5173.700000114.6S488 I612S488-G490 PolarHBondContact O-N 3.11Å; G490-I612 WeakPolarHBondContact O-CD1 3.46Å
491S59.9Low56.8Low22 Ų2254.6 Ų54.615%0.15430%0.299CS..PPolyproline II helixtrans-60.2151.9168.147.60000111.7S488 R616S488-S491 PolarHBondContact O-OG 2.98Å; S491-R616 PolarHBondContact O-NH1 2.93Å
492M73.6Confident58.5Low8 Ų851.9 Ų51.94%0.03929%0.285CS..PPolyproline II helixtrans-57.3143.9167-81.4-77.711000109T494 D497 I612 F615 R616 I637 L640M492-T494 PolarHBondContact O-N 3.09Å; M492-D497 HydrophobicContact CB-CB 4.32Å; M492-I612 HydrophobicContact CE-CB 4.17Å; M492-I612 HydrophobicContact CE-CD1 3.35Å; M492-I612 HydrophobicContact CE-CG1 3.37Å; M492-I612 HydrophobicContact CG-CD1 4.34Å; M492-F615 HydrophobicContact CE-CD1 3.73Å; M492-F615 HydrophobicContact CE-CE1 4.21Å; M492-F615 HydrophobicContact SD-CD1 3.92Å; M492-F615 HydrophobicContact SD-CE1 3.77Å; M492-R616 HydrophobicContact CE-CG 4.28Å; M492-I637 HydrophobicContact CE-CD1 3.85Å; M492-I637 HydrophobicContact CE-CG1 3.86Å; M492-I637 HydrophobicContact CE-CG2 4Å; M492-I637 HydrophobicContact CG-CG1 4.44Å; M492-I637 HydrophobicContact SD-CG1 4.14Å; M492-I637 HydrophobicContact SD-CG2 4.15Å; M492-L640 HydrophobicContact CG-CD1 4.15Å; M492-L640 HydrophobicContact SD-CD1 4.44Å
493P71.1Confident60.1Low2 Ų250.5 Ų50.51%0.01328%0.275CS..PPolyproline II helixtrans-54.9136.6170.71.81.2000108.8M495 L496 D497 D510 R616 L684P493-M495 PolarHBondContact O-N 2.94Å; P493-L496 HydrophobicContact CB-CG 4.41Å; P493-L496 HydrophobicContact CG-CB 4.13Å; P493-L496 HydrophobicContact CG-CD1 3.53Å; P493-L496 HydrophobicContact CG-CG 3.8Å; P493-L496 PolarHBondContact O-N 3.36Å; P493-D497 PolarHBondContact O-N 2.9Å; P493-D510 WeakPolarHBondContact CA-OD2 3.4Å; P493-D510 VanDerWaalsContact CB-OD2 3.3Å; P493-D510 WeakPolarHBondContact CB-OD2 3.2Å; P493-R616 VanDerWaalsContact CD-CZ 3.49Å; P493-R616 VanDerWaalsContact CD-NH1 3.3Å; P493-L684 HydrophobicContact CB-CD2 3.48Å; P493-L684 VanDerWaalsContact CB-CD2 3.48Å; P493-L684 HydrophobicContact CG-CD1 4.28Å; P493-L684 HydrophobicContact CG-CD2 4.04Å
494T71.8Confident61.7Low37 Ų3748.9 Ų48.923%0.22726%0.262CS..G310 helixtrans-56.2-33.5-174.9-45.50000112.3M249 M492 L496 D497M249-T494 HydrophobicContact CB-CG2 4.08Å; M249-T494 HydrophobicContact CE-CG2 3.67Å; M249-T494 HydrophobicContact CG-CG2 3.95Å; M492-T494 PolarHBondContact O-N 3.09Å; T494-L496 VanDerWaalsContact C-N 3.27Å; T494-L496 PolarHBondContact O-N 3Å; T494-D497 PolarHBondContact O-N 2.94Å
495M77Confident62.8Low55 Ų5547.3 Ų47.327%0.27125%0.254SS..G310 helixtrans-69.7-18.8177.3-110.9-176.7-75.900115F446 P493 H644 M683 L684F446-M495 HydrophobicContact CE1-CE 4.49Å; F446-M495 HydrophobicContact CE1-SD 4.34Å; F446-M495 HydrophobicContact CE2-CE 4.19Å; F446-M495 HydrophobicContact CZ-CE 3.63Å; F446-M495 HydrophobicContact CZ-SD 3.75Å; P493-M495 PolarHBondContact O-N 2.94Å; M495-H644 PolarHBondContact O-NE2 2.72Å; M495-M683 HydrophobicContact CE-CB 4.16Å; M495-M683 HydrophobicContact SD-CB 3.5Å; M495-M683 VanDerWaalsContact SD-CB 3.5Å; M495-M683 HydrophobicContact SD-CG 4.21Å; M495-M683 HydrophobicContact SD-SD 3.94Å; M495-L684 HydrophobicContact CB-CD2 4.31Å
496L79.6Confident64.3Low0 Ų047 Ų470%025%0.254CS..G310 helixtrans-95.5-7.8172.7-66.9-173.8000112.5P493 T494 F615 V619 H644 F646 L680 L684P493-L496 HydrophobicContact CB-CG 4.41Å; P493-L496 HydrophobicContact CG-CB 4.13Å; P493-L496 HydrophobicContact CG-CD1 3.53Å; P493-L496 HydrophobicContact CG-CG 3.8Å; P493-L496 PolarHBondContact O-N 3.36Å; T494-L496 VanDerWaalsContact C-N 3.27Å; T494-L496 PolarHBondContact O-N 3Å; L496-F615 HydrophobicContact CD1-CD1 4.5Å; L496-F615 HydrophobicContact CD1-CE1 3.78Å; L496-V619 HydrophobicContact CD1-CB 4.21Å; L496-V619 HydrophobicContact CD1-CG1 4.02Å; L496-V619 HydrophobicContact CD1-CG2 3.81Å; L496-V619 HydrophobicContact CD2-CG1 4.27Å; L496-H644 PolarHBondContact O-CE1 2.95Å; L496-F646 HydrophobicContact CD2-CE1 4.08Å; L496-F646 HydrophobicContact CD2-CZ 4.25Å; L496-L680 HydrophobicContact CD2-CB 4.31Å; L496-L680 HydrophobicContact CD2-CD1 3.7Å; L496-L680 HydrophobicContact CD2-CD2 4.02Å; L496-L680 HydrophobicContact CD2-CG 4.23Å; L496-L684 HydrophobicContact CD1-CD1 4.44Å
497D79.1Confident65.7Low28 Ų2844.6 Ų44.615%0.1524%0.241CC..SBendtrans-100.5162.6-178.7-145.4-29.9000111.1M492 P493 T494 R636M492-D497 HydrophobicContact CB-CB 4.32Å; P493-D497 PolarHBondContact O-N 2.9Å; T494-D497 PolarHBondContact O-N 2.94Å; D497-R636 IonicContact OD1-CZ 3.3Å; D497-R636 IonicContact OD1-NH1 2.63Å; D497-R636 IonicContact OD1-NH2 2.83Å; D497-R636 PolarHBondContact OD1-NH2 3.21Å; D497-R636 IonicContact OD2-CZ 3.61Å; D497-R636 IonicContact OD2-NH1 3.38Å; D497-R636 PolarHBondContact OD2-NH1 3.42Å; D497-R636 VanDerWaalsContact OD2-NH1 3.1Å; D497-R636 IonicContact OD2-NH2 3.96Å; D497-R636 PolarHBondContact OD2-NH2 3.45Å
498I74.3Confident67.2Low77 Ų7739.3 Ų39.340%0.39522%0.224SC..  trans-63.4137.1165.3-58.5171.1000107L500 L640 M643I498-L500 WeakPolarHBondContact O-CG 3.23Å; I498-L500 PolarHBondContact O-N 3.46Å; I498-L640 HydrophobicContact CG1-CD2 4.11Å; I498-M643 HydrophobicContact CD1-CE 4.01Å; I498-M643 HydrophobicContact CG1-CE 3.88Å; I498-M643 HydrophobicContact CG1-SD 4.45Å
499I69Low68.5Low16 Ų1637.2 Ų37.28%0.08221%0.207CC..  trans-61.7115.1174.4-62.3-167.5000109.4T248 I457T248-I499 HydrophobicContact CG2-CG2 3.75Å; I457-I499 VanDerWaalsContact CA-CD1 3.46Å; I457-I499 HydrophobicContact CB-CD1 3.72Å; I457-I499 HydrophobicContact CG1-CD1 3.83Å; I457-I499 HydrophobicContact CG2-CD1 3.53Å
500L69.4Low70.1Confident85 Ų8532.5 Ų32.545%0.44518%0.184SC..  trans-108.9148.9174.6-64.3175.7000109.9I498 Q502I498-L500 WeakPolarHBondContact O-CG 3.23Å; I498-L500 PolarHBondContact O-N 3.46Å; L500-Q502 PolarHBondContact O-N 3.34Å
501P72.6Confident71.1Confident48 Ų4834.6 Ų34.631%0.31218%0.183SC..  trans-58.7126167.5-23.534.7000111.2A174 P246 Q247 M461A174-P501 HydrophobicContact CB-CB 3.56Å; A174-P501 HydrophobicContact CB-CG 3.55Å; P246-P501 HydrophobicContact CB-CB 3.74Å; Q247-P501 CarbonylContact O-C 3.59Å; Q247-P501 WeakPolarHBondContact O-CA 3.47Å; M461-P501 HydrophobicContact SD-CG 4.28Å
502Q71.6Confident71.8Confident50 Ų5036.2 Ų36.223%0.23420%0.198CC..BIsolated β-bridgetrans-118154.4173.7-63.3-172-15.900109.9P246 Q247 L500P246-Q502 CarbonylContact C-O 3.58Å; P246-Q502 WeakPolarHBondContact CA-O 3.34Å; Q247-Q502 PolarHBondContact N-O 2.99Å; Q247-Q502 PolarHBondContact O-N 2.58Å; L500-Q502 PolarHBondContact O-N 3.34Å
503T71.3Confident72.3Confident15 Ų1537.9 Ų37.99%0.09221%0.209CC..  trans-112.2159.8172.949.70000110.6I244 P246 N505 T506 L714I244-T503 HydrophobicContact CG2-CG2 4.47Å; P246-T503 HydrophobicContact CB-CG2 4.05Å; P246-T503 HydrophobicContact CG-CG2 3.87Å; T503-N505 VanDerWaalsContact CB-OD1 3.24Å; T503-N505 WeakPolarHBondContact CB-OD1 3.22Å; T503-N505 PolarHBondContact O-N 3.44Å; T503-N505 VanDerWaalsContact O-N 3.16Å; T503-N505 PolarHBondContact OG1-OD1 2.96Å; T503-T506 PolarHBondContact N-OG1 2.67Å; T503-T506 CarbonylContact O-C 3.55Å; T503-T506 WeakPolarHBondContact O-CA 3.49Å; T503-T506 PolarHBondContact O-N 3.42Å; T503-T506 PolarHBondContact O-OG1 3.44Å; T503-T506 PolarHBondContact OG1-OG1 2.92Å; T503-L714 HydrophobicContact CG2-CD1 3.81Å; T503-L714 HydrophobicContact CG2-CD2 3.63Å; T503-L714 HydrophobicContact CG2-CG 3.76Å
504M70.2Confident72.9Confident41 Ų4139.5 Ų39.520%0.20222%0.22CC..THydrogen-bonded Turntrans-60.5-29.3-176.9-165.2-168.975.700113.6S239 M240 I244 T506 M712S239-M504 PolarHBondContact OG-SD 3.44Å; M240-M504 HydrophobicContact CB-CE 4.36Å; M240-M504 HydrophobicContact CE-CE 3.72Å; M240-M504 HydrophobicContact CE-SD 3.99Å; M240-M504 HydrophobicContact CG-CE 3.18Å; M240-M504 HydrophobicContact CG-SD 3.51Å; M240-M504 VanDerWaalsContact CG-SD 3.51Å; M240-M504 HydrophobicContact SD-CE 4.23Å; I244-M504 HydrophobicContact CD1-CB 4.28Å; I244-M504 HydrophobicContact CD1-CE 4.09Å; M504-T506 PolarHBondContact O-N 3.38Å; M504-M712 HydrophobicContact CE-CB 4.15Å; M504-M712 HydrophobicContact CE-CG 3.35Å; M504-M712 HydrophobicContact CE-SD 3.39Å; M504-M712 WeakPolarHBondContact CE-SD 3.33Å
505N70.7Confident73.5Confident16 Ų1647.8 Ų47.89%0.08625%0.253CS..THydrogen-bonded Turntrans-79.8-0.217468.5-38.6000114.1L485 T503 M712L485-N505 WeakPolarHBondContact CA-O 3.46Å; T503-N505 VanDerWaalsContact CB-OD1 3.24Å; T503-N505 WeakPolarHBondContact CB-OD1 3.22Å; T503-N505 PolarHBondContact O-N 3.44Å; T503-N505 VanDerWaalsContact O-N 3.16Å; T503-N505 PolarHBondContact OG1-OD1 2.96Å; N505-M712 HydrophobicContact CB-CB 3.98Å; N505-M712 WeakPolarHBondContact CB-O 3.46Å
506T71.2Confident74Confident38 Ų3847.2 Ų47.223%0.23325%0.252CS..  trans-128.1106.6177.261.10000108.8M486 T503 M504M486-T506 HydrophobicContact CB-CG2 4.1Å; T503-T506 PolarHBondContact N-OG1 2.67Å; T503-T506 CarbonylContact O-C 3.55Å; T503-T506 WeakPolarHBondContact O-CA 3.49Å; T503-T506 PolarHBondContact O-N 3.42Å; T503-T506 PolarHBondContact O-OG1 3.44Å; T503-T506 PolarHBondContact OG1-OG1 2.92Å; M504-T506 PolarHBondContact O-N 3.38Å
507F68.8Low74.5Confident33 Ų3349.6 Ų49.615%0.14528%0.277CS..  trans-121.9143.6172.251.4-96.9000109.3L485 L509 W698L485-F507 HydrophobicContact CD2-CD1 4.18Å; L485-F507 HydrophobicContact CD2-CE1 3.25Å; L485-F507 HydrophobicContact CD2-CZ 3.79Å; F507-L509 HydrophobicContact CD2-CD2 3.58Å; F507-L509 HydrophobicContact CD2-CG 3.85Å; F507-L509 HydrophobicContact CE2-CD1 4.14Å; F507-L509 HydrophobicContact CE2-CD2 3.49Å; F507-L509 VanDerWaalsContact CE2-CD2 3.49Å; F507-L509 HydrophobicContact CE2-CG 3.65Å; F507-W698 AromaticContact CD1-CD1 3.84Å; F507-W698 HydrophobicContact CD1-CG 4.2Å; F507-W698 HydrophobicContact CE1-CB 3.59Å; F507-W698 AromaticContact CE1-CD1 3.33Å; F507-W698 AromaticContact CE1-CD2 4Å; F507-W698 HydrophobicContact CE1-CD2 4Å; F507-W698 AromaticContact CE1-CG 3.35Å; F507-W698 HydrophobicContact CE1-CG 3.35Å; F507-W698 AromaticContact CE1-NE1 3.94Å; F507-W698 HydrophobicContact CE2-CB 4.41Å; F507-W698 AromaticContact CE2-CD1 3.91Å; F507-W698 HydrophobicContact CE2-CG 4.42Å; F507-W698 HydrophobicContact CZ-CB 3.37Å; F507-W698 AromaticContact CZ-CD1 3.4Å; F507-W698 VanDerWaalsContact CZ-CD1 3.4Å; F507-W698 AromaticContact CZ-CG 3.52Å; F507-W698 HydrophobicContact CZ-CG 3.52Å
508S68.4Low75Confident22 Ų2255.8 Ų55.815%0.15431%0.31CS..  trans-71.2129.1165-58.60000108.3K694S508-K694 PolarHBondContact O-NZ 3.13Å
509L68.9Low76Confident22 Ų2253 Ų5312%0.11530%0.296CS..  trans-94.9114.2159.1-68.1-174.5000108.1Y487 F507 E691 K694 G695Y487-L509 HydrophobicContact CD2-CD1 4.16Å; Y487-L509 HydrophobicContact CE2-CD1 3.28Å; Y487-L509 HydrophobicContact CE2-CG 4.32Å; F507-L509 HydrophobicContact CD2-CD2 3.58Å; F507-L509 HydrophobicContact CD2-CG 3.85Å; F507-L509 HydrophobicContact CE2-CD1 4.14Å; F507-L509 HydrophobicContact CE2-CD2 3.49Å; F507-L509 VanDerWaalsContact CE2-CD2 3.49Å; F507-L509 HydrophobicContact CE2-CG 3.65Å; L509-E691 WeakPolarHBondContact CD2-O 3.48Å; L509-K694 HydrophobicContact CD2-CB 4.37Å; L509-K694 HydrophobicContact CD2-CD 4.24Å; L509-K694 HydrophobicContact CD2-CG 4.24Å; L509-G695 VanDerWaalsContact CD1-CA 3.42Å
510D67.2Low77.2Confident37 Ų3755.1 Ų55.120%0.19831%0.312CS..  trans-75.4157.8166.3-148.9-55.3000110.4P493 R616 E691P493-D510 WeakPolarHBondContact CA-OD2 3.4Å; P493-D510 VanDerWaalsContact CB-OD2 3.3Å; P493-D510 WeakPolarHBondContact CB-OD2 3.2Å; D510-R616 IonicContact OD1-CZ 3.1Å; D510-R616 IonicContact OD1-NE 2.76Å; D510-R616 IonicContact OD1-NH1 3.99Å; D510-R616 IonicContact OD1-NH2 3.35Å; D510-R616 PolarHBondContact OD1-NH2 3.47Å; D510-R616 IonicContact OD2-CZ 2.66Å; D510-R616 IonicContact OD2-NH1 3.82Å; D510-R616 PolarHBondContact OD2-NH1 3.41Å; D510-R616 IonicContact OD2-NH2 3.64Å; D510-R616 PolarHBondContact OD2-NH2 3.01Å; D510-E691 HydrophobicContact CB-CB 3.9Å; D510-E691 HydrophobicContact CB-CG 3.63Å; D510-E691 PolarHBondContact N-OE2 3.06Å; D510-E691 WeakPolarHBondContact O-CB 3.36Å
511Y67.2Low78.5Confident75 Ų7558.1 Ų58.129%0.29432%0.324SS..  trans-106.1133.2162.665.4-93.2000108.6K613 R616Y511-K613 WeakPolarHBondContact OH-CA 3.34Å; Y511-K613 PolarHBondContact OH-O 3.23Å; Y511-R616 VanDerWaalsContact OH-CB 3.32Å; Y511-R616 WeakPolarHBondContact OH-CB 2.99Å; Y511-R616 WeakPolarHBondContact OH-CD 3.46Å
512A74.6Confident79.5Confident56 Ų5661.6 Ų61.646%0.46334%0.336SS..PPolyproline II helixtrans-54147.1-178.700000111.5
513C84.1Confident80.8Confident42 Ų4260.1 Ų60.128%0.28433%0.328SS..PPolyproline II helixtrans-50.2129.6171-67.60000109.5K515 C620C513-K515 PolarHBondContact O-N 3.24Å; C513-C620 WeakPolarHBondContact CA-SG 3.38Å; C513-C620 HydrophobicContact CB-CB 3.64Å; C513-C620 WeakPolarHBondContact CB-SG 3.4Å; C513-C620 WeakPolarHBondContact SG-CB 3.35Å; C513-C620 CovalentContact SG-SG 2.04Å; C513-C620 PolarHBondContact SG-SG 3.14Å
514P84.4Confident81.9Confident36 Ų3662.2 Ų62.223%0.23434%0.337CS..PPolyproline II helixtrans-65.9138.1-170.525-32.2000110.6V516 E617 F621P514-V516 HydrophobicContact CB-CG2 3.87Å; P514-V516 HydrophobicContact CG-CG2 4.11Å; P514-V516 PolarHBondContact O-N 3.43Å; P514-E617 HydrophobicContact CG-CG 4.09Å; P514-F621 HydrophobicContact CG-CE2 4.01Å; P514-F621 HydrophobicContact CG-CZ 3.86Å; P514-F621 WeakPolarHBondContact O-CZ 3.3Å
515K84.2Confident83.2Confident211 Ų21165.7 Ų65.792%0.91736%0.356SS*.  trans-87.3102.9166.6-64.4-177.3-178.3-179.60107.3C513C513-K515 PolarHBondContact O-N 3.24Å
516V87.6Confident84.4Confident43 Ų4366.4 Ų66.426%0.26136%0.359SS..PPolyproline II helixtrans-103.9147-175.3-166.10000109.6P514 P595 A596 Q599 F621P514-V516 HydrophobicContact CB-CG2 3.87Å; P514-V516 HydrophobicContact CG-CG2 4.11Å; P514-V516 PolarHBondContact O-N 3.43Å; V516-P595 HydrophobicContact CB-CB 4.42Å; V516-P595 HydrophobicContact CG1-CB 4.05Å; V516-P595 HydrophobicContact CG2-CB 3.53Å; V516-A596 HydrophobicContact CG1-CB 3.8Å; V516-Q599 PolarHBondContact O-OE1 3.38Å; V516-F621 HydrophobicContact CG2-CZ 4.04Å
517G88.9Confident85.7Confident51 Ų5164.6 Ų64.653%0.52635%0.348SS..PPolyproline II helixtrans-75.2173.5171.700000112.5
518N90.7Very high87Confident158 Ų15867.1 Ų67.185%0.84536%0.36SS*.PPolyproline II helixtrans-67.1157.9-179.8-66.2-14.1000112.3
519L94.3Very high88.3Confident17 Ų1768 Ų689%0.08936%0.363CS..PPolyproline II helixtrans-61.7151170.9-71170.7000110.7Q524 V527 P593 A596 L597 H600L519-Q524 HydrophobicContact CB-CB 4.23Å; L519-V527 HydrophobicContact CD1-CG2 4.44Å; L519-P593 HydrophobicContact CD2-CG 4.01Å; L519-A596 HydrophobicContact CD2-CB 3.58Å; L519-A596 HydrophobicContact CG-CB 4.16Å; L519-L597 HydrophobicContact CD1-CD2 4.12Å; L519-L597 HydrophobicContact CD2-CD2 3.8Å; L519-L597 HydrophobicContact CD2-CG 3.85Å; L519-H600 HydrophobicContact CD1-CB 4.15Å
520S95.1Very high89.4Confident62 Ų6273.1 Ų73.143%0.43440%0.397SS..PPolyproline II helixtrans-64.2155.1166.870.30000109.9E522 Y523 Q524S520-E522 PolarHBondContact O-N 2.86Å; S520-E522 VanDerWaalsContact O-N 3.08Å; S520-Y523 PolarHBondContact O-N 3.36Å; S520-Y523 VanDerWaalsContact O-N 3.11Å; S520-Y523 WeakPolarHBondContact OG-CD2 3.33Å; S520-Q524 WeakPolarHBondContact O-CB 3.28Å; S520-Q524 PolarHBondContact O-N 3.49Å
521H95.5Very high90.7Very high148 Ų14875.3 Ų75.369%0.68542%0.416SS*.Hα-helixtrans-51-36.6179.4-76.4-77.3000113.3Q524 N525H521-Q524 PolarHBondContact O-N 2.89Å; H521-N525 VanDerWaalsContact O-CB 3.31Å; H521-N525 WeakPolarHBondContact O-CB 3.49Å; H521-N525 PolarHBondContact O-N 3.02Å; H521-N525 PolarHBondContact O-ND2 3.16Å
522E95.6Very high92.1Very high120 Ų12072.1 Ų72.156%0.56140%0.404SS*.Hα-helixtrans-62.1-52.5177.9-173.3-168160.900112.6S520 Q524 F526 K587S520-E522 PolarHBondContact O-N 2.86Å; S520-E522 VanDerWaalsContact O-N 3.08Å; E522-Q524 VanDerWaalsContact C-N 3.35Å; E522-F526 PolarHBondContact O-N 3.16Å; E522-K587 WeakPolarHBondContact OE1-CE 3.2Å; E522-K587 IonicContact OE1-NZ 3.31Å; E522-K587 PolarHBondContact OE1-NZ 2.67Å
523Y96.9Very high93.1Very high20 Ų2076.4 Ų76.48%0.07841%0.413CS..Hα-helixtrans-68.5-37.3177.3-77.2-79.1000111.6S520 F526 V527 V570 K587 D589 P593 L597S520-Y523 PolarHBondContact O-N 3.36Å; S520-Y523 VanDerWaalsContact O-N 3.11Å; S520-Y523 WeakPolarHBondContact OG-CD2 3.33Å; Y523-F526 PolarHBondContact O-N 3.18Å; Y523-V527 VanDerWaalsContact O-CB 3.3Å; Y523-V527 WeakPolarHBondContact O-CB 3.11Å; Y523-V527 VanDerWaalsContact O-CG2 3.24Å; Y523-V527 WeakPolarHBondContact O-CG2 3.31Å; Y523-V527 PolarHBondContact O-N 2.91Å; Y523-V570 HydrophobicContact CE1-CG1 4.06Å; Y523-K587 HydrophobicContact CD1-CD 3.93Å; Y523-K587 HydrophobicContact CE1-CD 3.83Å; Y523-K587 HydrophobicContact CE1-CG 4.46Å; Y523-D589 VanDerWaalsContact CZ-OD2 3.27Å; Y523-D589 PolarHBondContact OH-OD2 3.42Å; Y523-P593 HydrophobicContact CD1-CG 4.37Å; Y523-P593 HydrophobicContact CD2-CG 3.66Å; Y523-P593 HydrophobicContact CE1-CG 4.32Å; Y523-P593 HydrophobicContact CE2-CG 3.61Å; Y523-P593 HydrophobicContact CG-CG 4.06Å; Y523-P593 WeakPolarHBondContact OH-CD 3.39Å; Y523-L597 HydrophobicContact CD1-CD1 4.5Å; Y523-L597 HydrophobicContact CD1-CD2 4.15Å; Y523-L597 HydrophobicContact CE1-CD1 4.49Å
524Q96.4Very high93.7Very high58 Ų5874.5 Ų74.527%0.27140%0.4SS..Hα-helixtrans-60.4-51.8178.6-175.5171.9100110.7L519 S520 H521 E522 F526 V527 E528L519-Q524 HydrophobicContact CB-CB 4.23Å; S520-Q524 WeakPolarHBondContact O-CB 3.28Å; S520-Q524 PolarHBondContact O-N 3.49Å; H521-Q524 PolarHBondContact O-N 2.89Å; E522-Q524 VanDerWaalsContact C-N 3.35Å; Q524-F526 VanDerWaalsContact C-N 3.27Å; Q524-F526 PolarHBondContact O-N 3.49Å; Q524-V527 PolarHBondContact O-N 3.04Å; Q524-E528 HydrophobicContact CG-CG 4.11Å; Q524-E528 WeakPolarHBondContact CG-OE2 3.38Å; Q524-E528 PolarHBondContact NE2-OE1 3.35Å; Q524-E528 PolarHBondContact NE2-OE2 3.26Å; Q524-E528 VanDerWaalsContact O-CB 3.28Å; Q524-E528 WeakPolarHBondContact O-CB 3.33Å; Q524-E528 WeakPolarHBondContact O-CG 3.35Å; Q524-E528 PolarHBondContact O-N 3.3Å
525N96.4Very high94.4Very high114 Ų11472.8 Ų72.861%0.6139%0.388SS*.Hα-helixtrans-58.3-39.2177.9-71.1-13.3000112.2H521 D529H521-N525 VanDerWaalsContact O-CB 3.31Å; H521-N525 WeakPolarHBondContact O-CB 3.49Å; H521-N525 PolarHBondContact O-N 3.02Å; H521-N525 PolarHBondContact O-ND2 3.16Å; N525-D529 PolarHBondContact O-N 3.45Å
526F96.7Very high95.1Very high31 Ų3162.7 Ų62.714%0.13635%0.345CS..Hα-helixtrans-68.3-42.9177.7-178.6-98.4000112.7E522 Y523 Q524 R568 V570 N585 K587E522-F526 PolarHBondContact O-N 3.16Å; Y523-F526 PolarHBondContact O-N 3.18Å; Q524-F526 VanDerWaalsContact C-N 3.27Å; Q524-F526 PolarHBondContact O-N 3.49Å; F526-R568 HydrophobicContact CD1-CB 4.33Å; F526-R568 HydrophobicContact CE1-CB 3.77Å; F526-R568 HydrophobicContact CE1-CG 4.42Å; F526-R568 HydrophobicContact CZ-CB 4.13Å; F526-R568 WeakPolarHBondContact O-CD 3.48Å; F526-R568 WeakPolarHBondContact O-CG 3.46Å; F526-V570 HydrophobicContact CD1-CG2 3.92Å; F526-V570 HydrophobicContact CE1-CG2 3.7Å; F526-N585 WeakPolarHBondContact CZ-O 3.38Å; F526-K587 HydrophobicContact CB-CD 4.39Å; F526-K587 HydrophobicContact CD1-CB 3.93Å; F526-K587 HydrophobicContact CD1-CD 4.22Å; F526-K587 HydrophobicContact CD2-CB 4.18Å; F526-K587 HydrophobicContact CE1-CB 3.56Å; F526-K587 HydrophobicContact CE2-CB 3.84Å; F526-K587 HydrophobicContact CG-CB 4.22Å; F526-K587 HydrophobicContact CG-CD 4.14Å; F526-K587 HydrophobicContact CZ-CB 3.51Å
527V97Very high95.6Very high0 Ų060.7 Ų60.70%033%0.332CS..Hα-helixtrans-76.6-33.7-176.6167.10000112.2L519 Y523 Q524 D529 T535 L597 H600 K602L519-V527 HydrophobicContact CD1-CG2 4.44Å; Y523-V527 VanDerWaalsContact O-CB 3.3Å; Y523-V527 WeakPolarHBondContact O-CB 3.11Å; Y523-V527 VanDerWaalsContact O-CG2 3.24Å; Y523-V527 WeakPolarHBondContact O-CG2 3.31Å; Y523-V527 PolarHBondContact O-N 2.91Å; Q524-V527 PolarHBondContact O-N 3.04Å; V527-D529 VanDerWaalsContact C-N 3.33Å; V527-T535 HydrophobicContact CG2-CG2 4.1Å; V527-L597 HydrophobicContact CG2-CD2 3.88Å; V527-H600 VanDerWaalsContact CG1-ND1 3.31Å; V527-H600 WeakPolarHBondContact CG1-ND1 3.01Å; V527-K602 HydrophobicContact CG1-CB 3.72Å; V527-K602 HydrophobicContact CG1-CG 4.39Å
528E96.5Very high96Very high86 Ų8658.2 Ų58.240%0.40231%0.307SS..THydrogen-bonded Turntrans-89.87.6-177.6-65.5-172.6150.800113.8Q524 P530 H600Q524-E528 HydrophobicContact CG-CG 4.11Å; Q524-E528 WeakPolarHBondContact CG-OE2 3.38Å; Q524-E528 PolarHBondContact NE2-OE1 3.35Å; Q524-E528 PolarHBondContact NE2-OE2 3.26Å; Q524-E528 VanDerWaalsContact O-CB 3.28Å; Q524-E528 WeakPolarHBondContact O-CB 3.33Å; Q524-E528 WeakPolarHBondContact O-CG 3.35Å; Q524-E528 PolarHBondContact O-N 3.3Å; E528-P530 WeakPolarHBondContact O-CD 3.46Å; E528-P530 VanDerWaalsContact O-N 3.13Å; E528-H600 IonicContact OE1-CE1 3.46Å; E528-H600 IonicContact OE1-NE2 3.39Å; E528-H600 PolarHBondContact OE1-NE2 3.15Å
529D95Very high96.4Very high42 Ų4250.7 Ų50.723%0.22527%0.267CS..  trans-49121177.3-171.6-57.5000111.1N525 V527 S531 S532 R568N525-D529 PolarHBondContact O-N 3.45Å; V527-D529 VanDerWaalsContact C-N 3.33Å; D529-S531 PolarHBondContact O-N 3.44Å; D529-S531 VanDerWaalsContact O-N 3.12Å; D529-S531 VanDerWaalsContact OD1-CB 3.32Å; D529-S531 WeakPolarHBondContact OD1-CB 3.38Å; D529-S531 PolarHBondContact OD1-N 3.39Å; D529-S531 PolarHBondContact OD1-OG 2.87Å; D529-S532 WeakPolarHBondContact O-CB 3.41Å; D529-S532 PolarHBondContact O-N 3.1Å; D529-R568 IonicContact OD1-NH2 3.54Å; D529-R568 IonicContact OD2-CZ 3.21Å; D529-R568 IonicContact OD2-NE 3.75Å; D529-R568 IonicContact OD2-NH1 3.87Å; D529-R568 IonicContact OD2-NH2 2.62Å; D529-R568 PolarHBondContact OD2-NH2 3.26Å
530P94.1Very high96.4Very high128 Ų12850.5 Ų50.583%0.83127%0.266SS*.THydrogen-bonded Turntrans-59.7-25.3-175-26.534.7000114.7E528 S532E528-P530 WeakPolarHBondContact O-CD 3.46Å; E528-P530 VanDerWaalsContact O-N 3.13Å; P530-S532 VanDerWaalsContact C-N 3.27Å; P530-S532 PolarHBondContact O-N 3.42Å
531S93.8Very high96.2Very high84 Ų8448.5 Ų48.559%0.58725%0.254SS*.THydrogen-bonded Turntrans-75.6-15.7176.869.40000113.2D529 R568D529-S531 PolarHBondContact O-N 3.44Å; D529-S531 VanDerWaalsContact O-N 3.12Å; D529-S531 VanDerWaalsContact OD1-CB 3.32Å; D529-S531 WeakPolarHBondContact OD1-CB 3.38Å; D529-S531 PolarHBondContact OD1-N 3.39Å; D529-S531 PolarHBondContact OD1-OG 2.87Å; S531-R568 PolarHBondContact OG-NH2 3.18Å
532S95.9Very high95.7Very high8 Ų848.5 Ų48.56%0.05626%0.255CS..  trans-81.2129.8-175.5-176.20000112.7D529 P530 G534 R568D529-S532 WeakPolarHBondContact O-CB 3.41Å; D529-S532 PolarHBondContact O-N 3.1Å; P530-S532 VanDerWaalsContact C-N 3.27Å; P530-S532 PolarHBondContact O-N 3.42Å; S532-G534 PolarHBondContact O-N 3.43Å; S532-G534 PolarHBondContact OG-N 3.31Å; S532-G534 VanDerWaalsContact OG-N 3.1Å; S532-G534 PolarHBondContact OG-O 3.05Å; S532-R568 WeakPolarHBondContact OG-CG 3.33Å; S532-R568 PolarHBondContact OG-N 2.87Å
533K96.2Very high95.2Very high146 Ų14648.4 Ų48.464%0.63526%0.257SS*.SBendtrans-74-13.4169-65.4-169.4-175.9179.20113Q566 Y567K533-Q566 HydrophobicContact CD-CB 4.21Å; K533-Q566 HydrophobicContact CD-CG 3.89Å; K533-Q566 HydrophobicContact CG-CB 4.31Å; K533-Q566 HydrophobicContact CG-CG 4.37Å; K533-Q566 PolarHBondContact N-O 2.74Å; K533-Y567 HydrophobicContact CB-CD1 3.93Å; K533-Y567 HydrophobicContact CB-CE1 3.57Å
534G97.3Very high94.8Very high1 Ų148.3 Ų48.31%0.0126%0.26CS..  trans153176.7178.900000112.2S532 Y567 R568 K602S532-G534 PolarHBondContact O-N 3.43Å; S532-G534 PolarHBondContact OG-N 3.31Å; S532-G534 VanDerWaalsContact OG-N 3.1Å; S532-G534 PolarHBondContact OG-O 3.05Å; G534-Y567 WeakPolarHBondContact O-CA 3.45Å; G534-R568 PolarHBondContact O-N 2.8Å; G534-K602 CarbonylContact C-O 3.49Å; G534-K602 WeakPolarHBondContact CA-O 3.5Å
535T98.5Very high94.6Very high0 Ų049.5 Ų49.50%027%0.269CS..EExtended strand (participates in β ladder)trans-112.2132.6-174.2-58.90000111.2V527 V537 R568 V570 K602 T603 I604V527-T535 HydrophobicContact CG2-CG2 4.1Å; T535-V537 HydrophobicContact CG2-CG2 4.21Å; T535-R568 CarbonylContact C-O 3.58Å; T535-R568 VanDerWaalsContact CA-O 3.25Å; T535-R568 WeakPolarHBondContact CA-O 3.42Å; T535-R568 HydrophobicContact CG2-CB 4.49Å; T535-V570 HydrophobicContact CG2-CG2 4.09Å; T535-K602 PolarHBondContact N-O 3.42Å; T535-T603 WeakPolarHBondContact O-CA 3.11Å; T535-I604 WeakPolarHBondContact O-CG1 2.71Å; T535-I604 PolarHBondContact O-N 3.48Å
536I98.6Very high94.4Very high0 Ų044.9 Ų44.90%024%0.243CC..EExtended strand (participates in β ladder)trans-102.4123.9169.6-55.2176.2000107.1L564 Y567 R568 I569 V570 L605 I607 L668I536-L564 HydrophobicContact CD1-CD1 3.95Å; I536-Y567 HydrophobicContact CD1-CG 4.39Å; I536-R568 PolarHBondContact N-O 3.19Å; I536-I569 HydrophobicContact CB-CG1 4.31Å; I536-I569 HydrophobicContact CD1-CG1 4.49Å; I536-I569 CarbonylContact O-C 3.51Å; I536-I569 WeakPolarHBondContact O-CA 3.38Å; I536-V570 PolarHBondContact O-N 3.28Å; I536-L605 WeakPolarHBondContact CA-O 3.49Å; I536-L605 HydrophobicContact CD1-CD2 4.38Å; I536-L605 HydrophobicContact CG1-CB 4.23Å; I536-L605 HydrophobicContact CG1-CD2 4.41Å; I536-L605 HydrophobicContact CG2-CB 4.24Å; I536-L605 HydrophobicContact CG2-CD2 4.03Å; I536-L605 HydrophobicContact CG2-CG 4.16Å; I536-I607 HydrophobicContact CG2-CD1 3.7Å; I536-I607 HydrophobicContact CG2-CG1 3.9Å; I536-L668 HydrophobicContact CD1-CD1 4.06Å
537V98.6Very high94.2Very high0 Ų050.2 Ų50.20%027%0.268CS..EExtended strand (participates in β ladder)trans-104.1132.3175.6179.90000108.5T535 V570 I592 L594 L597 T603 L605 F606 I607T535-V537 HydrophobicContact CG2-CG2 4.21Å; V537-V570 CarbonylContact C-O 3.5Å; V537-V570 WeakPolarHBondContact CA-O 3.4Å; V537-I592 HydrophobicContact CG1-CD1 3.67Å; V537-L594 HydrophobicContact CG1-CD1 3.58Å; V537-L597 HydrophobicContact CG2-CB 4.01Å; V537-T603 HydrophobicContact CG2-CG2 3.75Å; V537-L605 PolarHBondContact N-O 3.27Å; V537-F606 HydrophobicContact CB-CD2 4.18Å; V537-F606 HydrophobicContact CG1-CD2 4.13Å; V537-F606 HydrophobicContact CG1-CE2 4.33Å; V537-F606 CarbonylContact O-C 3.48Å; V537-F606 WeakPolarHBondContact O-CA 3.19Å; V537-F606 WeakPolarHBondContact O-CD2 3.27Å; V537-I607 PolarHBondContact O-N 3Å
538F98Very high93.9Very high0 Ų053.4 Ų53.40%030%0.301CS..EExtended strand (participates in β ladder)trans-124.7110179.3-174.1-157.1000110F540 W546 I557 F561 V570 W571 Q572 I607 F660F538-F540 HydrophobicContact CD2-CD2 4.23Å; F538-F540 AromaticContact CD2-CE2 3.88Å; F538-F540 HydrophobicContact CD2-CE2 3.88Å; F538-F540 AromaticContact CE2-CD2 3.86Å; F538-F540 HydrophobicContact CE2-CD2 3.86Å; F538-F540 AromaticContact CE2-CE2 3.2Å; F538-F540 HydrophobicContact CE2-CE2 3.2Å; F538-F540 AromaticContact CE2-CZ 3.55Å; F538-F540 HydrophobicContact CE2-CZ 3.55Å; F538-F540 HydrophobicContact CZ-CE2 4.08Å; F538-F540 HydrophobicContact CZ-CZ 4.02Å; F538-W546 AromaticContact CE1-CH2 3.77Å; F538-W546 HydrophobicContact CE1-CH2 3.77Å; F538-W546 AromaticContact CE1-CZ2 3.95Å; F538-W546 HydrophobicContact CE1-CZ2 3.95Å; F538-W546 HydrophobicContact CE2-CH2 4.36Å; F538-W546 HydrophobicContact CE2-CZ2 4.32Å; F538-W546 AromaticContact CZ-CH2 3.5Å; F538-W546 HydrophobicContact CZ-CH2 3.5Å; F538-W546 AromaticContact CZ-CZ2 3.79Å; F538-W546 HydrophobicContact CZ-CZ2 3.79Å; F538-I557 HydrophobicContact CD1-CG2 4.22Å; F538-I557 HydrophobicContact CE1-CD1 4.07Å; F538-I557 HydrophobicContact CE1-CG2 3.47Å; F538-I557 VanDerWaalsContact CE1-CG2 3.47Å; F538-I557 HydrophobicContact CZ-CD1 3.89Å; F538-I557 HydrophobicContact CZ-CG2 4.17Å; F538-F561 HydrophobicContact CB-CZ 4.27Å; F538-F561 AromaticContact CD1-CE2 3.74Å; F538-F561 HydrophobicContact CD1-CE2 3.74Å; F538-F561 AromaticContact CD1-CZ 3.53Å; F538-F561 HydrophobicContact CD1-CZ 3.53Å; F538-F561 HydrophobicContact CE1-CE2 4.22Å; F538-F561 HydrophobicContact CE1-CZ 4.07Å; F538-F561 HydrophobicContact CG-CZ 4.14Å; F538-V570 PolarHBondContact N-O 2.88Å; F538-W571 HydrophobicContact CB-CB 4.43Å; F538-W571 HydrophobicContact CB-CG 4.3Å; F538-W571 HydrophobicContact CD1-CB 4.47Å; F538-W571 AromaticContact CD1-CD1 3.27Å; F538-W571 AromaticContact CD1-CD2 3.7Å; F538-W571 HydrophobicContact CD1-CD2 3.7Å; F538-W571 AromaticContact CD1-CE2 3.49Å; F538-W571 VanDerWaalsContact CD1-CE2 3.49Å; F538-W571 AromaticContact CD1-CG 3.6Å; F538-W571 HydrophobicContact CD1-CG 3.6Å; F538-W571 HydrophobicContact CD1-CZ2 4.19Å; F538-W571 AromaticContact CD1-NE1 3.23Å; F538-W571 AromaticContact CE1-CD1 3.94Å; F538-W571 HydrophobicContact CE1-CD2 4.1Å; F538-W571 AromaticContact CE1-CE2 3.46Å; F538-W571 VanDerWaalsContact CE1-CE2 3.46Å; F538-W571 HydrophobicContact CE1-CG 4.4Å; F538-W571 AromaticContact CE1-CZ2 3.71Å; F538-W571 HydrophobicContact CE1-CZ2 3.71Å; F538-W571 AromaticContact CE1-NE1 3.38Å; F538-W571 AromaticContact CG-CD1 3.8Å; F538-W571 HydrophobicContact CG-CG 4.31Å; F538-Q572 PolarHBondContact O-N 2.89Å; F538-I607 WeakPolarHBondContact CA-O 3.5Å; F538-I607 HydrophobicContact CB-CB 4.24Å; F538-I607 HydrophobicContact CD2-CB 3.44Å; F538-I607 VanDerWaalsContact CD2-CB 3.44Å; F538-I607 HydrophobicContact CD2-CG2 3.38Å; F538-I607 WeakPolarHBondContact CD2-O 3.42Å; F538-I607 HydrophobicContact CE2-CB 3.97Å; F538-I607 HydrophobicContact CE2-CG2 3.33Å; F538-I607 HydrophobicContact CG-CB 4.09Å; F538-I607 HydrophobicContact CG-CG2 4.31Å; F538-I607 HydrophobicContact CZ-CG2 4.3Å; F538-F660 HydrophobicContact CZ-CZ 4.36Å
539S97.6Very high93.8Very high0 Ų050.6 Ų50.60%029%0.293CS..EExtended strand (participates in β ladder)trans-147.6130.4-179.4169.80000112.9G541 Q572 I607S539-G541 PolarHBondContact OG-N 3.42Å; S539-Q572 PolarHBondContact OG-OE1 3.48Å; S539-I607 PolarHBondContact N-O 3.41Å
540F95.3Very high93.7Very high13 Ų1352.1 Ų52.16%0.05731%0.305CS..  trans-105.718.1178.4-75.9-164.5000113.4F538 A544 W546 T608 H609 I628 L630F538-F540 HydrophobicContact CD2-CD2 4.23Å; F538-F540 AromaticContact CD2-CE2 3.88Å; F538-F540 HydrophobicContact CD2-CE2 3.88Å; F538-F540 AromaticContact CE2-CD2 3.86Å; F538-F540 HydrophobicContact CE2-CD2 3.86Å; F538-F540 AromaticContact CE2-CE2 3.2Å; F538-F540 HydrophobicContact CE2-CE2 3.2Å; F538-F540 AromaticContact CE2-CZ 3.55Å; F538-F540 HydrophobicContact CE2-CZ 3.55Å; F538-F540 HydrophobicContact CZ-CE2 4.08Å; F538-F540 HydrophobicContact CZ-CZ 4.02Å; F540-A544 HydrophobicContact CB-CB 3.43Å; F540-A544 VanDerWaalsContact CB-CB 3.43Å; F540-A544 HydrophobicContact CD1-CB 4.31Å; F540-A544 HydrophobicContact CG-CB 4.41Å; F540-A544 WeakPolarHBondContact O-CB 3.48Å; F540-W546 HydrophobicContact CD1-CH2 4.16Å; F540-W546 AromaticContact CD1-CZ2 3.85Å; F540-W546 HydrophobicContact CD1-CZ2 3.85Å; F540-W546 AromaticContact CE1-CH2 3.99Å; F540-W546 HydrophobicContact CE1-CH2 3.99Å; F540-W546 HydrophobicContact CE1-CZ2 4.11Å; F540-W546 HydrophobicContact CG-CZ2 4.06Å; F540-W546 HydrophobicContact CZ-CH2 4.44Å; F540-T608 VanDerWaalsContact CE2-C 3.42Å; F540-H609 VanDerWaalsContact C-ND1 3.31Å; F540-H609 VanDerWaalsContact CA-ND1 3.34Å; F540-H609 WeakPolarHBondContact CA-ND1 3.37Å; F540-H609 HydrophobicContact CB-CB 4.34Å; F540-H609 HydrophobicContact CD1-CB 4.35Å; F540-H609 HydrophobicContact CD2-CB 4.08Å; F540-H609 HydrophobicContact CE2-CB 4.44Å; F540-H609 HydrophobicContact CG-CB 4.03Å; F540-H609 PolarHBondContact O-CE1 3.42Å; F540-H609 PolarHBondContact O-ND1 3.02Å; F540-H609 PolarHBondContact O-NE2 3.34Å; F540-I628 HydrophobicContact CE1-CB 4.45Å; F540-I628 HydrophobicContact CZ-CB 3.75Å; F540-I628 HydrophobicContact CZ-CD1 3.85Å; F540-I628 HydrophobicContact CZ-CG1 4.32Å; F540-I628 HydrophobicContact CZ-CG2 4.28Å; F540-L630 HydrophobicContact CD1-CD1 4.01Å; F540-L630 HydrophobicContact CD1-CD2 4.4Å; F540-L630 HydrophobicContact CD1-CG 4.45Å; F540-L630 HydrophobicContact CE1-CD2 4.16Å
541G89.6Confident93.7Very high19 Ų1948.9 Ų48.920%0.19628%0.283CS..  trans69.7-162.5177.800000113.4S539 Q572S539-G541 PolarHBondContact OG-N 3.42Å; G541-Q572 PolarHBondContact O-NE2 3.06Å; G541-Q572 VanDerWaalsContact O-NE2 3.17Å
542H85.3Confident93.7Very high149 Ų14951.3 Ų51.369%0.6929%0.285SS*.SBendtrans-90.3-18-172.267.4-81.2000114.2W591H542-W591 HydrophobicContact CB-CH2 4.3Å; H542-W591 HydrophobicContact CB-CZ3 4.06Å
543L85.8Confident93.6Very high118 Ų11852.5 Ų52.562%0.61829%0.29SS*.SBendtrans-90.5-11.2-177.9-65178.9000113.5F631L543-F631 HydrophobicContact CD1-CZ 4.35Å
544A87.4Confident93.6Very high17 Ų1745.9 Ų45.914%0.1426%0.261CS..  trans-95.3104.2177.800000109.5F540 L630F540-A544 HydrophobicContact CB-CB 3.43Å; F540-A544 VanDerWaalsContact CB-CB 3.43Å; F540-A544 HydrophobicContact CD1-CB 4.31Å; F540-A544 HydrophobicContact CG-CB 4.41Å; F540-A544 WeakPolarHBondContact O-CB 3.48Å; A544-L630 HydrophobicContact CB-CD1 3.72Å
545D92.1Very high93.4Very high84 Ų8451 Ų5145%0.44929%0.285SS..  trans-88.1115.7172.2-174.34.5000110.4Q547 G548 N574D545-Q547 PolarHBondContact O-N 2.73Å; D545-Q547 WeakPolarHBondContact OD1-CB 3.37Å; D545-Q547 WeakPolarHBondContact OD1-CG 3.47Å; D545-Q547 PolarHBondContact OD1-N 2.73Å; D545-G548 PolarHBondContact O-N 3.35Å; D545-N574 PolarHBondContact OD1-ND2 3.22Å
546W94Very high93.3Very high16 Ų1651.6 Ų51.66%0.06129%0.29CS..G310 helixtrans-69.5-16178.3-73.298.4000113.4F538 F540 G548 A549 I554 I557 W571 Q572 F573 N574F538-W546 AromaticContact CE1-CH2 3.77Å; F538-W546 HydrophobicContact CE1-CH2 3.77Å; F538-W546 AromaticContact CE1-CZ2 3.95Å; F538-W546 HydrophobicContact CE1-CZ2 3.95Å; F538-W546 HydrophobicContact CE2-CH2 4.36Å; F538-W546 HydrophobicContact CE2-CZ2 4.32Å; F538-W546 AromaticContact CZ-CH2 3.5Å; F538-W546 HydrophobicContact CZ-CH2 3.5Å; F538-W546 AromaticContact CZ-CZ2 3.79Å; F538-W546 HydrophobicContact CZ-CZ2 3.79Å; F540-W546 HydrophobicContact CD1-CH2 4.16Å; F540-W546 AromaticContact CD1-CZ2 3.85Å; F540-W546 HydrophobicContact CD1-CZ2 3.85Å; F540-W546 AromaticContact CE1-CH2 3.99Å; F540-W546 HydrophobicContact CE1-CH2 3.99Å; F540-W546 HydrophobicContact CE1-CZ2 4.11Å; F540-W546 HydrophobicContact CG-CZ2 4.06Å; F540-W546 HydrophobicContact CZ-CH2 4.44Å; W546-G548 PolarHBondContact O-N 2.82Å; W546-A549 HydrophobicContact CE3-CB 3.98Å; W546-A549 WeakPolarHBondContact O-CB 3.19Å; W546-A549 PolarHBondContact O-N 2.86Å; W546-I554 HydrophobicContact CE3-CG1 4.19Å; W546-I554 HydrophobicContact CZ3-CG1 4.48Å; W546-I557 HydrophobicContact CH2-CD1 4.03Å; W546-I557 HydrophobicContact CZ3-CD1 4.07Å; W546-W571 AromaticContact CE2-NE1 3.65Å; W546-W571 HydrophobicContact CE3-CZ2 4.31Å; W546-W571 HydrophobicContact CH2-CZ2 4.04Å; W546-W571 HydrophobicContact CZ2-CZ2 4.26Å; W546-W571 AromaticContact CZ2-NE1 3.47Å; W546-W571 HydrophobicContact CZ3-CZ2 4.06Å; W546-W571 AromaticContact NE1-NE1 3.93Å; W546-Q572 PolarHBondContact NE1-O 3.12Å; W546-Q572 VanDerWaalsContact NE1-O 3.08Å; W546-F573 HydrophobicContact CB-CD2 3.65Å; W546-F573 HydrophobicContact CB-CE2 3.54Å; W546-F573 HydrophobicContact CB-CZ 4.35Å; W546-F573 AromaticContact CD1-CD2 3.81Å; W546-F573 AromaticContact CD2-CD2 3.58Å; W546-F573 HydrophobicContact CD2-CD2 3.58Å; W546-F573 AromaticContact CD2-CE2 3.86Å; W546-F573 HydrophobicContact CD2-CE2 3.86Å; W546-F573 HydrophobicContact CE3-CD2 4.07Å; W546-F573 AromaticContact CE3-CE2 3.94Å; W546-F573 HydrophobicContact CE3-CE2 3.94Å; W546-F573 AromaticContact CG-CD2 3.38Å; W546-F573 HydrophobicContact CG-CD2 3.38Å; W546-F573 AromaticContact CG-CE2 3.71Å; W546-F573 HydrophobicContact CG-CE2 3.71Å; W546-F573 HydrophobicContact CG-CG 4.34Å; W546-N574 WeakPolarHBondContact CB-OD1 3.5Å; W546-N574 PolarHBondContact N-OD1 2.9Å
547Q92Very high93.1Very high143 Ų14351.6 Ų51.667%0.66829%0.29SS*.G310 helixtrans-66.2-28.5173.5-62.2179.126.500112.2D545 N574D545-Q547 PolarHBondContact O-N 2.73Å; D545-Q547 WeakPolarHBondContact OD1-CB 3.37Å; D545-Q547 WeakPolarHBondContact OD1-CG 3.47Å; D545-Q547 PolarHBondContact OD1-N 2.73Å; Q547-N574 PolarHBondContact NE2-O 2.98Å
548G91.2Very high93Very high68 Ų6851.9 Ų51.970%0.70129%0.292SS*.G310 helixtrans-88.2-0.3175.700000114.5D545 W546D545-G548 PolarHBondContact O-N 3.35Å; W546-G548 PolarHBondContact O-N 2.82Å
549A92.9Very high92.8Very high27 Ų2753 Ų5322%0.22330%0.301CS..SBendtrans-81.3142.7-179.300000111.3W546 V551 I554W546-A549 HydrophobicContact CE3-CB 3.98Å; W546-A549 WeakPolarHBondContact O-CB 3.19Å; W546-A549 PolarHBondContact O-N 2.86Å; A549-V551 PolarHBondContact O-N 3Å; A549-I554 HydrophobicContact CB-CD1 4.2Å; A549-I554 HydrophobicContact CB-CG1 4.24Å
550P94Very high92.7Very high74 Ų7453 Ų5348%0.48130%0.301SS..  trans-57.9136.2175.4-22.932.8000111.8E552 I553 I554P550-E552 WeakPolarHBondContact CB-OE2 3.35Å; P550-E552 PolarHBondContact O-N 3.31Å; P550-I553 HydrophobicContact CB-CB 4.42Å; P550-I553 HydrophobicContact CB-CG1 3.96Å; P550-I553 HydrophobicContact CG-CG1 4.19Å; P550-I553 WeakPolarHBondContact O-CB 3.42Å; P550-I553 PolarHBondContact O-N 3.44Å; P550-I553 VanDerWaalsContact O-N 3.08Å; P550-I554 PolarHBondContact O-N 3.02Å
551V93.7Very high92.7Very high60 Ų6052.4 Ų52.436%0.36430%0.298SS..Hα-helixtrans-61-36.8-176.4174.80000111A549 I553 I554 Q555 M579A549-V551 PolarHBondContact O-N 3Å; V551-I553 PolarHBondContact O-N 2.75Å; V551-I554 PolarHBondContact O-N 3.44Å; V551-Q555 HydrophobicContact CG1-CG 4.22Å; V551-Q555 WeakPolarHBondContact O-CB 3.02Å; V551-Q555 WeakPolarHBondContact O-CG 3.44Å; V551-Q555 PolarHBondContact O-N 3.25Å; V551-M579 HydrophobicContact CG1-CE 4.35Å; V551-M579 HydrophobicContact CG1-SD 4.34Å; V551-M579 HydrophobicContact CG2-CE 4.23Å
552E93.8Very high92.9Very high134 Ų13456.2 Ų56.263%0.62631%0.311SS*.Hα-helixtrans-60.2-36.6178.8-5775.7-164.900111.4P550 A556P550-E552 WeakPolarHBondContact CB-OE2 3.35Å; P550-E552 PolarHBondContact O-N 3.31Å; E552-A556 WeakPolarHBondContact O-CB 3.41Å; E552-A556 PolarHBondContact O-N 3.29Å
553I94.6Very high93.3Very high34 Ų3452.1 Ų52.117%0.17429%0.293CS..Hα-helixtrans-71.4-44.6178.6-63.5-70.3000110.5P550 V551 Q555 A556 I557 L655P550-I553 HydrophobicContact CB-CB 4.42Å; P550-I553 HydrophobicContact CB-CG1 3.96Å; P550-I553 HydrophobicContact CG-CG1 4.19Å; P550-I553 WeakPolarHBondContact O-CB 3.42Å; P550-I553 PolarHBondContact O-N 3.44Å; P550-I553 VanDerWaalsContact O-N 3.08Å; V551-I553 PolarHBondContact O-N 2.75Å; I553-Q555 VanDerWaalsContact C-N 3.33Å; I553-Q555 PolarHBondContact O-N 3.37Å; I553-A556 PolarHBondContact O-N 3.4Å; I553-I557 HydrophobicContact CG2-CD1 3.91Å; I553-I557 WeakPolarHBondContact O-CD1 3.37Å; I553-I557 VanDerWaalsContact O-CG1 3.26Å; I553-I557 WeakPolarHBondContact O-CG1 3.3Å; I553-I557 PolarHBondContact O-N 3.36Å; I553-L655 HydrophobicContact CD1-CB 3.83Å; I553-L655 HydrophobicContact CG2-CD2 4.02Å
554I95.2Very high93.8Very high6 Ų646.5 Ų46.53%0.03126%0.263CS..Hα-helixtrans-60.6-45.7176.9-62172.9000110W546 A549 P550 V551 I557 S558 W571 F573 M579 V580W546-I554 HydrophobicContact CE3-CG1 4.19Å; W546-I554 HydrophobicContact CZ3-CG1 4.48Å; A549-I554 HydrophobicContact CB-CD1 4.2Å; A549-I554 HydrophobicContact CB-CG1 4.24Å; P550-I554 PolarHBondContact O-N 3.02Å; V551-I554 PolarHBondContact O-N 3.44Å; I554-I557 PolarHBondContact O-N 3.27Å; I554-S558 WeakPolarHBondContact O-CB 3.33Å; I554-S558 PolarHBondContact O-N 2.99Å; I554-W571 HydrophobicContact CG2-CH2 4.22Å; I554-F573 HydrophobicContact CD1-CE2 4.19Å; I554-F573 HydrophobicContact CD1-CZ 4.31Å; I554-F573 HydrophobicContact CG1-CE2 4.42Å; I554-F573 HydrophobicContact CG2-CE2 4.13Å; I554-F573 HydrophobicContact CG2-CZ 4.14Å; I554-M579 HydrophobicContact CG2-CB 4.38Å; I554-V580 HydrophobicContact CG2-CG1 3.57Å
555Q94.1Very high94.1Very high108 Ų10849.9 Ų49.951%0.50528%0.284SS..Hα-helixtrans-64.4-43.4177.5-72.4177.7-1100112.1V551 I553 I557 S558 A559V551-Q555 HydrophobicContact CG1-CG 4.22Å; V551-Q555 WeakPolarHBondContact O-CB 3.02Å; V551-Q555 WeakPolarHBondContact O-CG 3.44Å; V551-Q555 PolarHBondContact O-N 3.25Å; I553-Q555 VanDerWaalsContact C-N 3.33Å; I553-Q555 PolarHBondContact O-N 3.37Å; Q555-I557 VanDerWaalsContact C-N 3.33Å; Q555-I557 PolarHBondContact O-N 2.95Å; Q555-S558 PolarHBondContact O-N 2.99Å; Q555-A559 VanDerWaalsContact O-CB 3.28Å; Q555-A559 WeakPolarHBondContact O-CB 3.2Å; Q555-A559 PolarHBondContact O-N 3.42Å
556A94.8Very high94.3Very high13 Ų1348.2 Ų48.211%0.10727%0.273CS..Hα-helixtrans-59.3-42.7176.600000112.3E552 I553 A560E552-A556 WeakPolarHBondContact O-CB 3.41Å; E552-A556 PolarHBondContact O-N 3.29Å; I553-A556 PolarHBondContact O-N 3.4Å; A556-A560 WeakPolarHBondContact O-CB 3.33Å; A556-A560 PolarHBondContact O-N 2.96Å; A556-A560 VanDerWaalsContact O-N 3.12Å
557I95.9Very high94.5Very high1 Ų148.2 Ų48.21%0.00527%0.273CS..Hα-helixtrans-66.2-49.1176.2-65.9162.5000110.5F538 W546 I553 I554 Q555 A559 A560 F561 W571 L655 F660F538-I557 HydrophobicContact CD1-CG2 4.22Å; F538-I557 HydrophobicContact CE1-CD1 4.07Å; F538-I557 HydrophobicContact CE1-CG2 3.47Å; F538-I557 VanDerWaalsContact CE1-CG2 3.47Å; F538-I557 HydrophobicContact CZ-CD1 3.89Å; F538-I557 HydrophobicContact CZ-CG2 4.17Å; W546-I557 HydrophobicContact CH2-CD1 4.03Å; W546-I557 HydrophobicContact CZ3-CD1 4.07Å; I553-I557 HydrophobicContact CG2-CD1 3.91Å; I553-I557 WeakPolarHBondContact O-CD1 3.37Å; I553-I557 VanDerWaalsContact O-CG1 3.26Å; I553-I557 WeakPolarHBondContact O-CG1 3.3Å; I553-I557 PolarHBondContact O-N 3.36Å; I554-I557 PolarHBondContact O-N 3.27Å; Q555-I557 VanDerWaalsContact C-N 3.33Å; Q555-I557 PolarHBondContact O-N 2.95Å; I557-A559 VanDerWaalsContact C-N 3.34Å; I557-A559 PolarHBondContact O-N 3.16Å; I557-A560 WeakPolarHBondContact O-CB 3.37Å; I557-A560 PolarHBondContact O-N 2.81Å; I557-A560 VanDerWaalsContact O-N 3.12Å; I557-F561 HydrophobicContact CG2-CD2 3.99Å; I557-F561 HydrophobicContact CG2-CE1 4.45Å; I557-F561 HydrophobicContact CG2-CE2 3.47Å; I557-F561 VanDerWaalsContact CG2-CE2 3.47Å; I557-F561 HydrophobicContact CG2-CZ 3.74Å; I557-F561 PolarHBondContact O-N 3.23Å; I557-W571 HydrophobicContact CB-CH2 4.33Å; I557-W571 HydrophobicContact CG2-CH2 3.86Å; I557-W571 HydrophobicContact CG2-CZ2 4.18Å; I557-W571 HydrophobicContact CG2-CZ3 4.21Å; I557-L655 HydrophobicContact CD1-CD2 4.02Å; I557-L655 HydrophobicContact CG1-CD2 3.86Å; I557-F660 HydrophobicContact CB-CD1 4.28Å; I557-F660 HydrophobicContact CB-CE1 4.02Å; I557-F660 HydrophobicContact CG1-CD1 4.1Å; I557-F660 HydrophobicContact CG1-CE1 3.98Å; I557-F660 HydrophobicContact CG1-CZ 4.31Å; I557-F660 HydrophobicContact CG2-CD1 4.23Å; I557-F660 HydrophobicContact CG2-CE1 3.5Å; I557-F660 HydrophobicContact CG2-CZ 4.04Å
558S94.9Very high94.8Very high5 Ų543 Ų434%0.03525%0.247CC..Hα-helixtrans-55.6-47.4178.5-168.80000111.6I554 Q555 A560 F561 E562 K583I554-S558 WeakPolarHBondContact O-CB 3.33Å; I554-S558 PolarHBondContact O-N 2.99Å; Q555-S558 PolarHBondContact O-N 2.99Å; S558-A560 VanDerWaalsContact C-N 3.3Å; S558-A560 PolarHBondContact O-N 3.17Å; S558-F561 PolarHBondContact O-N 3.38Å; S558-E562 PolarHBondContact O-N 2.92Å; S558-K583 PolarHBondContact OG-NZ 2.95Å
559A94.1Very high95.1Very high23 Ų2339.8 Ų39.819%0.1921%0.214CC..Hα-helixtrans-71.1-20.4179.700000114Q555 I557 R657Q555-A559 VanDerWaalsContact O-CB 3.28Å; Q555-A559 WeakPolarHBondContact O-CB 3.2Å; Q555-A559 PolarHBondContact O-N 3.42Å; I557-A559 VanDerWaalsContact C-N 3.34Å; I557-A559 PolarHBondContact O-N 3.16Å; A559-R657 HydrophobicContact CB-CG 4.03Å; A559-R657 PolarHBondContact O-NE 3.25Å; A559-R657 VanDerWaalsContact O-NE 3.13Å
560A95.8Very high95.3Very high0 Ų038.5 Ų38.50%020%0.203CC..Hα-helixtrans-80.4-37.4172.800000111.6A556 I557 S558 E562 Q563 R657 F660 M664A556-A560 WeakPolarHBondContact O-CB 3.33Å; A556-A560 PolarHBondContact O-N 2.96Å; A556-A560 VanDerWaalsContact O-N 3.12Å; I557-A560 WeakPolarHBondContact O-CB 3.37Å; I557-A560 PolarHBondContact O-N 2.81Å; I557-A560 VanDerWaalsContact O-N 3.12Å; S558-A560 VanDerWaalsContact C-N 3.3Å; S558-A560 PolarHBondContact O-N 3.17Å; A560-E562 VanDerWaalsContact C-N 3.26Å; A560-E562 PolarHBondContact O-N 2.81Å; A560-Q563 WeakPolarHBondContact O-CB 3.18Å; A560-Q563 PolarHBondContact O-N 3.33Å; A560-Q563 VanDerWaalsContact O-N 3.16Å; A560-R657 HydrophobicContact CB-CG 4.3Å; A560-F660 HydrophobicContact CB-CB 4.39Å; A560-F660 HydrophobicContact CB-CD1 3.66Å; A560-F660 HydrophobicContact CB-CG 4.5Å; A560-M664 HydrophobicContact CB-CE 3.89Å
561F96.2Very high95.5Very high1 Ų135 Ų350%0.00418%0.18CC..Hα-helixtrans-63.4-30.3174.3-71.9-23.4000113.1F538 I557 S558 Q563 L564 I569 W571 L586 I607 F660 M664F538-F561 HydrophobicContact CB-CZ 4.27Å; F538-F561 AromaticContact CD1-CE2 3.74Å; F538-F561 HydrophobicContact CD1-CE2 3.74Å; F538-F561 AromaticContact CD1-CZ 3.53Å; F538-F561 HydrophobicContact CD1-CZ 3.53Å; F538-F561 HydrophobicContact CE1-CE2 4.22Å; F538-F561 HydrophobicContact CE1-CZ 4.07Å; F538-F561 HydrophobicContact CG-CZ 4.14Å; I557-F561 HydrophobicContact CG2-CD2 3.99Å; I557-F561 HydrophobicContact CG2-CE1 4.45Å; I557-F561 HydrophobicContact CG2-CE2 3.47Å; I557-F561 VanDerWaalsContact CG2-CE2 3.47Å; I557-F561 HydrophobicContact CG2-CZ 3.74Å; I557-F561 PolarHBondContact O-N 3.23Å; S558-F561 PolarHBondContact O-N 3.38Å; F561-Q563 PolarHBondContact O-N 3.41Å; F561-L564 PolarHBondContact O-N 3.04Å; F561-L564 VanDerWaalsContact O-N 3.1Å; F561-I569 HydrophobicContact CB-CD1 3.51Å; F561-I569 HydrophobicContact CD1-CD1 3.6Å; F561-I569 HydrophobicContact CD1-CG2 4.34Å; F561-I569 HydrophobicContact CD2-CD1 4.31Å; F561-I569 HydrophobicContact CD2-CG2 4.06Å; F561-I569 HydrophobicContact CE1-CD1 4.34Å; F561-I569 HydrophobicContact CE1-CG2 4.16Å; F561-I569 HydrophobicContact CE2-CG2 3.89Å; F561-I569 HydrophobicContact CG-CD1 3.56Å; F561-I569 HydrophobicContact CG-CG2 4.28Å; F561-I569 HydrophobicContact CZ-CG2 3.95Å; F561-W571 HydrophobicContact CD2-CE3 4.15Å; F561-W571 HydrophobicContact CD2-CZ3 4.29Å; F561-W571 HydrophobicContact CE2-CD2 4.16Å; F561-W571 AromaticContact CE2-CE3 3.78Å; F561-W571 HydrophobicContact CE2-CE3 3.78Å; F561-W571 HydrophobicContact CE2-CZ3 4.12Å; F561-L586 HydrophobicContact CD2-CD1 4.35Å; F561-I607 HydrophobicContact CE1-CD1 3.9Å; F561-I607 HydrophobicContact CZ-CD1 4.2Å; F561-F660 HydrophobicContact CD1-CE1 4.17Å; F561-F660 AromaticContact CE1-CE1 3.6Å; F561-F660 HydrophobicContact CE1-CE1 3.6Å; F561-F660 HydrophobicContact CE1-CZ 4.04Å; F561-F660 AromaticContact CZ-CE1 3.92Å; F561-F660 HydrophobicContact CZ-CE1 3.92Å; F561-F660 HydrophobicContact CZ-CZ 4.15Å; F561-M664 HydrophobicContact CD1-CE 3.92Å; F561-M664 HydrophobicContact CD1-SD 3.87Å; F561-M664 HydrophobicContact CE1-CE 4.13Å; F561-M664 HydrophobicContact CE1-SD 3.57Å; F561-M664 VanDerWaalsContact CE1-SD 3.57Å
562E92.8Very high95.6Very high100 Ų10032.7 Ų32.747%0.46717%0.166SC..THydrogen-bonded Turntrans-60.3-26.7173-71.4173-17400113.6S558 A560 L564 K583S558-E562 PolarHBondContact O-N 2.92Å; A560-E562 VanDerWaalsContact C-N 3.26Å; A560-E562 PolarHBondContact O-N 2.81Å; E562-L564 PolarHBondContact O-N 3.32Å; E562-K583 HydrophobicContact CG-CD 3.98Å; E562-K583 WeakPolarHBondContact OE1-CE 3.14Å; E562-K583 IonicContact OE1-NZ 2.92Å; E562-K583 PolarHBondContact OE1-NZ 3.47Å
563Q94.8Very high95.7Very high63 Ų6326.4 Ų26.429%0.29414%0.137SC..THydrogen-bonded Turntrans-81.73.3179.2-62.2-17879.100112.9A560 F561 Y661A560-Q563 WeakPolarHBondContact O-CB 3.18Å; A560-Q563 PolarHBondContact O-N 3.33Å; A560-Q563 VanDerWaalsContact O-N 3.16Å; F561-Q563 PolarHBondContact O-N 3.41Å; Q563-Y661 HydrophobicContact CB-CD2 3.52Å; Q563-Y661 HydrophobicContact CB-CE2 3.37Å; Q563-Y661 HydrophobicContact CB-CG 4.41Å; Q563-Y661 HydrophobicContact CG-CD2 4.36Å; Q563-Y661 HydrophobicContact CG-CE2 4.45Å
564L95.4Very high95.7Very high0 Ų027.7 Ų27.70%014%0.144CC..  trans-125.448-178.3-65.7176000112.6I536 F561 E562 Q566 Y567 N585 Y661 M664 W665 L668I536-L564 HydrophobicContact CD1-CD1 3.95Å; F561-L564 PolarHBondContact O-N 3.04Å; F561-L564 VanDerWaalsContact O-N 3.1Å; E562-L564 PolarHBondContact O-N 3.32Å; L564-Q566 PolarHBondContact O-N 3.2Å; L564-Q566 VanDerWaalsContact O-N 3.1Å; L564-Y567 HydrophobicContact CB-CD2 4.05Å; L564-Y567 HydrophobicContact CD2-CD2 3.99Å; L564-Y567 HydrophobicContact CD2-CE2 4.08Å; L564-Y567 HydrophobicContact CG-CD2 4.48Å; L564-Y567 PolarHBondContact O-N 2.85Å; L564-N585 PolarHBondContact O-ND2 3.44Å; L564-Y661 HydrophobicContact CD2-CD2 4.42Å; L564-Y661 HydrophobicContact CD2-CE2 3.78Å; L564-Y661 HydrophobicContact CG-CD2 4.25Å; L564-Y661 HydrophobicContact CG-CE2 4.01Å; L564-M664 HydrophobicContact CD1-CB 4.31Å; L564-M664 HydrophobicContact CD1-CE 3.85Å; L564-M664 HydrophobicContact CD1-SD 4.02Å; L564-W665 HydrophobicContact CD2-CE3 3.74Å; L564-W665 HydrophobicContact CD2-CZ3 3.88Å; L564-L668 HydrophobicContact CD1-CD1 4.27Å; L564-L668 HydrophobicContact CD2-CD1 4.43Å
565P94.6Very high95.6Very high88 Ų8828 Ų2857%0.57115%0.148SC*.THydrogen-bonded Turntrans-61.6-22.5-176.728-37000113.7Y567P565-Y567 PolarHBondContact O-N 2.73Å
566Q95.9Very high95.5Very high48 Ų4826.8 Ų26.822%0.22415%0.145CC..THydrogen-bonded Turntrans-75.8-3.1177.171.5-82.719.900114.5K533 L564K533-Q566 HydrophobicContact CD-CB 4.21Å; K533-Q566 HydrophobicContact CD-CG 3.89Å; K533-Q566 HydrophobicContact CG-CB 4.31Å; K533-Q566 HydrophobicContact CG-CG 4.37Å; K533-Q566 PolarHBondContact N-O 2.74Å; L564-Q566 PolarHBondContact O-N 3.2Å; L564-Q566 VanDerWaalsContact O-N 3.1Å
567Y97.7Very high95.3Very high16 Ų1629.5 Ų29.56%0.06316%0.16CC..SBendtrans-120.7147.6178-63.8-76.9000110.8K533 G534 I536 L564 P565 N585 I604 W665 L668K533-Y567 HydrophobicContact CB-CD1 3.93Å; K533-Y567 HydrophobicContact CB-CE1 3.57Å; G534-Y567 WeakPolarHBondContact O-CA 3.45Å; I536-Y567 HydrophobicContact CD1-CG 4.39Å; L564-Y567 HydrophobicContact CB-CD2 4.05Å; L564-Y567 HydrophobicContact CD2-CD2 3.99Å; L564-Y567 HydrophobicContact CD2-CE2 4.08Å; L564-Y567 HydrophobicContact CG-CD2 4.48Å; L564-Y567 PolarHBondContact O-N 2.85Å; P565-Y567 PolarHBondContact O-N 2.73Å; Y567-N585 WeakPolarHBondContact O-CB 3.49Å; Y567-N585 PolarHBondContact O-ND2 3.42Å; Y567-I604 HydrophobicContact CD1-CD1 3.62Å; Y567-I604 HydrophobicContact CE1-CD1 3.33Å; Y567-W665 HydrophobicContact CE2-CZ3 4.42Å; Y567-L668 HydrophobicContact CD2-CD1 4.36Å; Y567-L668 HydrophobicContact CE1-CD2 4.27Å; Y567-L668 HydrophobicContact CE2-CD1 3.95Å
568R97.8Very high95Very high34 Ų3433.6 Ų33.613%0.12819%0.189CC..EExtended strand (participates in β ladder)trans-87.2139171.1-65.8-73.5162179.6-2.9109.5F526 D529 S531 S532 G534 T535 I536 P584F526-R568 HydrophobicContact CD1-CB 4.33Å; F526-R568 HydrophobicContact CE1-CB 3.77Å; F526-R568 HydrophobicContact CE1-CG 4.42Å; F526-R568 HydrophobicContact CZ-CB 4.13Å; F526-R568 WeakPolarHBondContact O-CD 3.48Å; F526-R568 WeakPolarHBondContact O-CG 3.46Å; D529-R568 IonicContact OD1-NH2 3.54Å; D529-R568 IonicContact OD2-CZ 3.21Å; D529-R568 IonicContact OD2-NE 3.75Å; D529-R568 IonicContact OD2-NH1 3.87Å; D529-R568 IonicContact OD2-NH2 2.62Å; D529-R568 PolarHBondContact OD2-NH2 3.26Å; S531-R568 PolarHBondContact OG-NH2 3.18Å; S532-R568 WeakPolarHBondContact OG-CG 3.33Å; S532-R568 PolarHBondContact OG-N 2.87Å; G534-R568 PolarHBondContact O-N 2.8Å; T535-R568 CarbonylContact C-O 3.58Å; T535-R568 VanDerWaalsContact CA-O 3.25Å; T535-R568 WeakPolarHBondContact CA-O 3.42Å; T535-R568 HydrophobicContact CG2-CB 4.49Å; I536-R568 PolarHBondContact N-O 3.19Å; R568-P584 PolarHBondContact NH1-O 3.26Å
569I98.1Very high94.7Very high0 Ų036.7 Ų36.70%020%0.203CC..EExtended strand (participates in β ladder)trans-125.7121.1-176.1-54174.2000108.1I536 F561 N585 L586 K587I536-I569 HydrophobicContact CB-CG1 4.31Å; I536-I569 HydrophobicContact CD1-CG1 4.49Å; I536-I569 CarbonylContact O-C 3.51Å; I536-I569 WeakPolarHBondContact O-CA 3.38Å; F561-I569 HydrophobicContact CB-CD1 3.51Å; F561-I569 HydrophobicContact CD1-CD1 3.6Å; F561-I569 HydrophobicContact CD1-CG2 4.34Å; F561-I569 HydrophobicContact CD2-CD1 4.31Å; F561-I569 HydrophobicContact CD2-CG2 4.06Å; F561-I569 HydrophobicContact CE1-CD1 4.34Å; F561-I569 HydrophobicContact CE1-CG2 4.16Å; F561-I569 HydrophobicContact CE2-CG2 3.89Å; F561-I569 HydrophobicContact CG-CD1 3.56Å; F561-I569 HydrophobicContact CG-CG2 4.28Å; F561-I569 HydrophobicContact CZ-CG2 3.95Å; I569-N585 PolarHBondContact N-O 3.39Å; I569-L586 HydrophobicContact CB-CD1 3.69Å; I569-L586 HydrophobicContact CG2-CD1 3.5Å; I569-L586 CarbonylContact O-C 3.58Å; I569-L586 WeakPolarHBondContact O-CA 3.39Å; I569-K587 PolarHBondContact O-N 3.38Å
570V98.1Very high94.5Very high0 Ų035.6 Ų35.60%019%0.194CC..EExtended strand (participates in β ladder)trans-107.3113.6173.1-179.30000107.7Y523 F526 T535 I536 V537 F538 K587 I592 L597Y523-V570 HydrophobicContact CE1-CG1 4.06Å; F526-V570 HydrophobicContact CD1-CG2 3.92Å; F526-V570 HydrophobicContact CE1-CG2 3.7Å; T535-V570 HydrophobicContact CG2-CG2 4.09Å; I536-V570 PolarHBondContact O-N 3.28Å; V537-V570 CarbonylContact C-O 3.5Å; V537-V570 WeakPolarHBondContact CA-O 3.4Å; F538-V570 PolarHBondContact N-O 2.88Å; V570-K587 WeakPolarHBondContact CA-O 3.37Å; V570-K587 HydrophobicContact CG2-CB 4.49Å; V570-I592 HydrophobicContact CG1-CB 4.3Å; V570-I592 HydrophobicContact CG1-CD1 4.11Å; V570-I592 HydrophobicContact CG1-CG2 3.82Å; V570-L597 HydrophobicContact CB-CD1 4.41Å; V570-L597 HydrophobicContact CG1-CD1 3.78Å; V570-L597 HydrophobicContact CG2-CD2 4.31Å
571W97.3Very high94Very high0 Ų038.3 Ų38.30%021%0.214CC..EExtended strand (participates in β ladder)trans-114.5115.2-176.6-173.12.9000110.9F538 W546 I554 I557 F561 F573 V580 L586 K587 I588 D589F538-W571 HydrophobicContact CB-CB 4.43Å; F538-W571 HydrophobicContact CB-CG 4.3Å; F538-W571 HydrophobicContact CD1-CB 4.47Å; F538-W571 AromaticContact CD1-CD1 3.27Å; F538-W571 AromaticContact CD1-CD2 3.7Å; F538-W571 HydrophobicContact CD1-CD2 3.7Å; F538-W571 AromaticContact CD1-CE2 3.49Å; F538-W571 VanDerWaalsContact CD1-CE2 3.49Å; F538-W571 AromaticContact CD1-CG 3.6Å; F538-W571 HydrophobicContact CD1-CG 3.6Å; F538-W571 HydrophobicContact CD1-CZ2 4.19Å; F538-W571 AromaticContact CD1-NE1 3.23Å; F538-W571 AromaticContact CE1-CD1 3.94Å; F538-W571 HydrophobicContact CE1-CD2 4.1Å; F538-W571 AromaticContact CE1-CE2 3.46Å; F538-W571 VanDerWaalsContact CE1-CE2 3.46Å; F538-W571 HydrophobicContact CE1-CG 4.4Å; F538-W571 AromaticContact CE1-CZ2 3.71Å; F538-W571 HydrophobicContact CE1-CZ2 3.71Å; F538-W571 AromaticContact CE1-NE1 3.38Å; F538-W571 AromaticContact CG-CD1 3.8Å; F538-W571 HydrophobicContact CG-CG 4.31Å; W546-W571 AromaticContact CE2-NE1 3.65Å; W546-W571 HydrophobicContact CE3-CZ2 4.31Å; W546-W571 HydrophobicContact CH2-CZ2 4.04Å; W546-W571 HydrophobicContact CZ2-CZ2 4.26Å; W546-W571 AromaticContact CZ2-NE1 3.47Å; W546-W571 HydrophobicContact CZ3-CZ2 4.06Å; W546-W571 AromaticContact NE1-NE1 3.93Å; I554-W571 HydrophobicContact CG2-CH2 4.22Å; I557-W571 HydrophobicContact CB-CH2 4.33Å; I557-W571 HydrophobicContact CG2-CH2 3.86Å; I557-W571 HydrophobicContact CG2-CZ2 4.18Å; I557-W571 HydrophobicContact CG2-CZ3 4.21Å; F561-W571 HydrophobicContact CD2-CE3 4.15Å; F561-W571 HydrophobicContact CD2-CZ3 4.29Å; F561-W571 HydrophobicContact CE2-CD2 4.16Å; F561-W571 AromaticContact CE2-CE3 3.78Å; F561-W571 HydrophobicContact CE2-CE3 3.78Å; F561-W571 HydrophobicContact CE2-CZ3 4.12Å; W571-F573 HydrophobicContact CD2-CB 4.18Å; W571-F573 HydrophobicContact CD2-CD2 4.44Å; W571-F573 AromaticContact CE2-CD2 3.66Å; W571-F573 HydrophobicContact CG-CB 4.08Å; W571-F573 HydrophobicContact CH2-CD2 4.29Å; W571-F573 HydrophobicContact CH2-CE2 4.37Å; W571-F573 AromaticContact CZ2-CD2 3.56Å; W571-F573 HydrophobicContact CZ2-CD2 3.56Å; W571-F573 AromaticContact CZ2-CE2 3.93Å; W571-F573 HydrophobicContact CZ2-CE2 3.93Å; W571-F573 HydrophobicContact CZ2-CG 4.37Å; W571-F573 AromaticContact NE1-CD2 3.84Å; W571-F573 PolarHBondContact O-N 3.39Å; W571-V580 HydrophobicContact CE3-CB 4.39Å; W571-V580 HydrophobicContact CE3-CG1 4.33Å; W571-V580 HydrophobicContact CH2-CB 4.44Å; W571-V580 HydrophobicContact CH2-CG1 3.54Å; W571-V580 HydrophobicContact CZ3-CB 3.82Å; W571-V580 HydrophobicContact CZ3-CG1 3.36Å; W571-L586 HydrophobicContact CB-CD1 4.03Å; W571-L586 HydrophobicContact CE3-CD1 4.35Å; W571-L586 HydrophobicContact CE3-CD2 4.32Å; W571-K587 PolarHBondContact N-O 3.33Å; W571-I588 WeakPolarHBondContact O-CA 3.38Å; W571-D589 PolarHBondContact O-N 3.09Å
572Q96.8Very high93.4Very high12 Ų1242.1 Ų42.16%0.05625%0.253CS..EExtended strand (participates in β ladder)trans-73.3106.3166.6-173-178-36.300109.9F538 S539 G541 W546 D589 P590 W591 I592F538-Q572 PolarHBondContact O-N 2.89Å; S539-Q572 PolarHBondContact OG-OE1 3.48Å; G541-Q572 PolarHBondContact O-NE2 3.06Å; G541-Q572 VanDerWaalsContact O-NE2 3.17Å; W546-Q572 PolarHBondContact NE1-O 3.12Å; W546-Q572 VanDerWaalsContact NE1-O 3.08Å; Q572-D589 CarbonylContact C-O 3.46Å; Q572-D589 VanDerWaalsContact CA-O 3.29Å; Q572-D589 WeakPolarHBondContact CA-O 3.3Å; Q572-P590 WeakPolarHBondContact CG-O 3.39Å; Q572-W591 VanDerWaalsContact NE2-CE3 3.29Å; Q572-W591 VanDerWaalsContact NE2-CZ3 3.31Å; Q572-I592 HydrophobicContact CB-CD1 3.99Å; Q572-I592 HydrophobicContact CB-CG1 4.03Å; Q572-I592 HydrophobicContact CB-CG2 4.13Å; Q572-I592 HydrophobicContact CG-CG1 4.5Å
573F95.9Very high93.1Very high3 Ų339.3 Ų39.31%0.01324%0.239CC..  trans-145.6123.3-171.9-177.7-100.2000111W546 I554 W571 G575 V577 V580 I588 D589 P590W546-F573 HydrophobicContact CB-CD2 3.65Å; W546-F573 HydrophobicContact CB-CE2 3.54Å; W546-F573 HydrophobicContact CB-CZ 4.35Å; W546-F573 AromaticContact CD1-CD2 3.81Å; W546-F573 AromaticContact CD2-CD2 3.58Å; W546-F573 HydrophobicContact CD2-CD2 3.58Å; W546-F573 AromaticContact CD2-CE2 3.86Å; W546-F573 HydrophobicContact CD2-CE2 3.86Å; W546-F573 HydrophobicContact CE3-CD2 4.07Å; W546-F573 AromaticContact CE3-CE2 3.94Å; W546-F573 HydrophobicContact CE3-CE2 3.94Å; W546-F573 AromaticContact CG-CD2 3.38Å; W546-F573 HydrophobicContact CG-CD2 3.38Å; W546-F573 AromaticContact CG-CE2 3.71Å; W546-F573 HydrophobicContact CG-CE2 3.71Å; W546-F573 HydrophobicContact CG-CG 4.34Å; I554-F573 HydrophobicContact CD1-CE2 4.19Å; I554-F573 HydrophobicContact CD1-CZ 4.31Å; I554-F573 HydrophobicContact CG1-CE2 4.42Å; I554-F573 HydrophobicContact CG2-CE2 4.13Å; I554-F573 HydrophobicContact CG2-CZ 4.14Å; W571-F573 HydrophobicContact CD2-CB 4.18Å; W571-F573 HydrophobicContact CD2-CD2 4.44Å; W571-F573 AromaticContact CE2-CD2 3.66Å; W571-F573 HydrophobicContact CG-CB 4.08Å; W571-F573 HydrophobicContact CH2-CD2 4.29Å; W571-F573 HydrophobicContact CH2-CE2 4.37Å; W571-F573 AromaticContact CZ2-CD2 3.56Å; W571-F573 HydrophobicContact CZ2-CD2 3.56Å; W571-F573 AromaticContact CZ2-CE2 3.93Å; W571-F573 HydrophobicContact CZ2-CE2 3.93Å; W571-F573 HydrophobicContact CZ2-CG 4.37Å; W571-F573 AromaticContact NE1-CD2 3.84Å; W571-F573 PolarHBondContact O-N 3.39Å; F573-G575 WeakPolarHBondContact CE1-O 3.4Å; F573-V577 HydrophobicContact CD1-CG2 4.46Å; F573-V580 HydrophobicContact CD1-CG2 3.84Å; F573-V580 HydrophobicContact CE1-CG2 3.59Å; F573-V580 HydrophobicContact CZ-CG1 4.38Å; F573-V580 HydrophobicContact CZ-CG2 4.19Å; F573-I588 HydrophobicContact CB-CG2 3.81Å; F573-I588 HydrophobicContact CD1-CG2 4.09Å; F573-I588 HydrophobicContact CG-CG2 4.39Å; F573-D589 PolarHBondContact N-O 2.83Å; F573-P590 WeakPolarHBondContact O-CA 3.49Å
574N94.1Very high92.7Very high61 Ų6141.7 Ų41.733%0.32626%0.26SS..  trans-112.812.5-179.571.6-40.8000112.8D545 W546 Q547 P590D545-N574 PolarHBondContact OD1-ND2 3.22Å; W546-N574 WeakPolarHBondContact CB-OD1 3.5Å; W546-N574 PolarHBondContact N-OD1 2.9Å; Q547-N574 PolarHBondContact NE2-O 2.98Å; N574-P590 HydrophobicContact CB-CB 4.44Å
575G92.6Very high92.7Very high11 Ų1142.3 Ų42.311%0.11326%0.264CS..SBendtrans-87.1-162.2176.900000112.8F573 V577F573-G575 WeakPolarHBondContact CE1-O 3.4Å; G575-V577 PolarHBondContact O-N 2.87Å
576N92.4Very high92.7Very high84 Ų8439 Ų3945%0.44924%0.241SC..  trans-71101.4178.1-175.2-5.1000111.6S578 M579N576-S578 PolarHBondContact ND2-OG 3.36Å; N576-S578 PolarHBondContact O-N 2.88Å; N576-S578 VanDerWaalsContact O-N 3.14Å; N576-S578 WeakPolarHBondContact OD1-CB 3.34Å; N576-S578 PolarHBondContact OD1-N 2.67Å; N576-S578 VanDerWaalsContact OD1-N 3.12Å; N576-S578 PolarHBondContact OD1-OG 3.09Å; N576-M579 HydrophobicContact CB-CE 4.18Å; N576-M579 HydrophobicContact CB-CG 4.22Å; N576-M579 HydrophobicContact CB-SD 4.16Å; N576-M579 WeakPolarHBondContact O-CB 3.5Å; N576-M579 PolarHBondContact O-N 3.32Å; N576-M579 VanDerWaalsContact O-N 3.1Å
577V90.8Very high92.7Very high70 Ų7037.9 Ų37.942%0.42424%0.235SC..G310 helixtrans-58.9-27.5-176.6177.70000112.8F573 G575 M579 V580 S581F573-V577 HydrophobicContact CD1-CG2 4.46Å; G575-V577 PolarHBondContact O-N 2.87Å; V577-M579 PolarHBondContact O-N 2.89Å; V577-M579 VanDerWaalsContact O-N 3.15Å; V577-V580 VanDerWaalsContact O-CG2 3.31Å; V577-V580 WeakPolarHBondContact O-CG2 3.46Å; V577-V580 PolarHBondContact O-N 3.25Å; V577-S581 VanDerWaalsContact O-CB 3.26Å; V577-S581 WeakPolarHBondContact O-CB 3.44Å; V577-S581 PolarHBondContact O-N 3.15Å; V577-S581 PolarHBondContact O-OG 2.95Å; V577-S581 VanDerWaalsContact O-OG 3.11Å
578S89.7Confident92.6Very high86 Ų8638.6 Ų38.660%0.60124%0.24SC*.G310 helixtrans-61.7-21.9177.865.90000114N576 V580N576-S578 PolarHBondContact ND2-OG 3.36Å; N576-S578 PolarHBondContact O-N 2.88Å; N576-S578 VanDerWaalsContact O-N 3.14Å; N576-S578 WeakPolarHBondContact OD1-CB 3.34Å; N576-S578 PolarHBondContact OD1-N 2.67Å; N576-S578 VanDerWaalsContact OD1-N 3.12Å; N576-S578 PolarHBondContact OD1-OG 3.09Å; S578-V580 VanDerWaalsContact C-N 3.3Å
579M87.3Confident92.4Very high70 Ų7038.6 Ų38.635%0.34524%0.243SC..G310 helixtrans-77-17.5177.6-61.5-179.6174.500113.3V551 I554 N576 V577V551-M579 HydrophobicContact CG1-CE 4.35Å; V551-M579 HydrophobicContact CG1-SD 4.34Å; V551-M579 HydrophobicContact CG2-CE 4.23Å; I554-M579 HydrophobicContact CG2-CB 4.38Å; N576-M579 HydrophobicContact CB-CE 4.18Å; N576-M579 HydrophobicContact CB-CG 4.22Å; N576-M579 HydrophobicContact CB-SD 4.16Å; N576-M579 WeakPolarHBondContact O-CB 3.5Å; N576-M579 PolarHBondContact O-N 3.32Å; N576-M579 VanDerWaalsContact O-N 3.1Å; V577-M579 PolarHBondContact O-N 2.89Å; V577-M579 VanDerWaalsContact O-N 3.15Å
580V91Very high92.2Very high0 Ų043.1 Ų43.10%027%0.272CS..THydrogen-bonded Turntrans-130.3-19.1-166.1-68.60000113.4I554 W571 F573 V577 S578 L586 I588I554-V580 HydrophobicContact CG2-CG1 3.57Å; W571-V580 HydrophobicContact CE3-CB 4.39Å; W571-V580 HydrophobicContact CE3-CG1 4.33Å; W571-V580 HydrophobicContact CH2-CB 4.44Å; W571-V580 HydrophobicContact CH2-CG1 3.54Å; W571-V580 HydrophobicContact CZ3-CB 3.82Å; W571-V580 HydrophobicContact CZ3-CG1 3.36Å; F573-V580 HydrophobicContact CD1-CG2 3.84Å; F573-V580 HydrophobicContact CE1-CG2 3.59Å; F573-V580 HydrophobicContact CZ-CG1 4.38Å; F573-V580 HydrophobicContact CZ-CG2 4.19Å; V577-V580 VanDerWaalsContact O-CG2 3.31Å; V577-V580 WeakPolarHBondContact O-CG2 3.46Å; V577-V580 PolarHBondContact O-N 3.25Å; S578-V580 VanDerWaalsContact C-N 3.3Å; V580-L586 VanDerWaalsContact O-CD2 3.29Å; V580-L586 WeakPolarHBondContact O-CD2 3.32Å; V580-I588 HydrophobicContact CB-CD1 3.87Å; V580-I588 HydrophobicContact CG2-CD1 3.48Å; V580-I588 VanDerWaalsContact CG2-CD1 3.48Å
581S85Confident92.1Very high58 Ų5850.9 Ų50.941%0.40630%0.301SS..  trans-72.9179.7-179.165.20000113.9V577V577-S581 VanDerWaalsContact O-CB 3.26Å; V577-S581 WeakPolarHBondContact O-CB 3.44Å; V577-S581 PolarHBondContact O-N 3.15Å; V577-S581 PolarHBondContact O-OG 2.95Å; V577-S581 VanDerWaalsContact O-OG 3.11Å
582G82.5Confident92Very high81 Ų8151 Ų5184%0.83530%0.302SS*.  trans914.2175.700000115.7
583K86.6Confident92Very high40 Ų4052.6 Ų52.617%0.17431%0.313CS..  trans-110.6125.5-175.7-61.9168.2173.176.60111.1S558 E562 N585 L586S558-K583 PolarHBondContact OG-NZ 2.95Å; E562-K583 HydrophobicContact CG-CD 3.98Å; E562-K583 WeakPolarHBondContact OE1-CE 3.14Å; E562-K583 IonicContact OE1-NZ 2.92Å; E562-K583 PolarHBondContact OE1-NZ 3.47Å; K583-N585 VanDerWaalsContact C-N 3.26Å; K583-N585 PolarHBondContact O-N 3.44Å; K583-L586 HydrophobicContact CB-CB 3.98Å; K583-L586 HydrophobicContact CD-CD2 4.11Å; K583-L586 PolarHBondContact O-N 3.09Å
584P88.1Confident92Very high114 Ų11453.3 Ų53.374%0.7432%0.317SS*.THydrogen-bonded Turntrans-68.7-22.9-173.927.1-35000113.8R568R568-P584 PolarHBondContact NH1-O 3.26Å
585N94Very high92Very high13 Ų1352.1 Ų52.17%0.0731%0.313CS..THydrogen-bonded Turntrans-91.33.4179.371.2-47.7000113.7F526 L564 Y567 I569 K583F526-N585 WeakPolarHBondContact CZ-O 3.38Å; L564-N585 PolarHBondContact O-ND2 3.44Å; Y567-N585 WeakPolarHBondContact O-CB 3.49Å; Y567-N585 PolarHBondContact O-ND2 3.42Å; I569-N585 PolarHBondContact N-O 3.39Å; K583-N585 VanDerWaalsContact C-N 3.26Å; K583-N585 PolarHBondContact O-N 3.44Å
586L95.4Very high92.2Very high19 Ų1952 Ų5210%0.09931%0.311CS..EExtended strand (participates in β ladder)trans-117.7121.6-176.8-176.162.9000111.2F561 I569 W571 V580 K583 I588F561-L586 HydrophobicContact CD2-CD1 4.35Å; I569-L586 HydrophobicContact CB-CD1 3.69Å; I569-L586 HydrophobicContact CG2-CD1 3.5Å; I569-L586 CarbonylContact O-C 3.58Å; I569-L586 WeakPolarHBondContact O-CA 3.39Å; W571-L586 HydrophobicContact CB-CD1 4.03Å; W571-L586 HydrophobicContact CE3-CD1 4.35Å; W571-L586 HydrophobicContact CE3-CD2 4.32Å; V580-L586 VanDerWaalsContact O-CD2 3.29Å; V580-L586 WeakPolarHBondContact O-CD2 3.32Å; K583-L586 HydrophobicContact CB-CB 3.98Å; K583-L586 HydrophobicContact CD-CD2 4.11Å; K583-L586 PolarHBondContact O-N 3.09Å; L586-I588 HydrophobicContact CD1-CG1 4.37Å; L586-I588 HydrophobicContact CD2-CD1 3.69Å; L586-I588 HydrophobicContact CD2-CG1 3.95Å; L586-I588 HydrophobicContact CG-CD1 4.02Å; L586-I588 HydrophobicContact CG-CG1 3.7Å
587K95.4Very high92.5Very high23 Ų2348 Ų4810%0.129%0.29CS..EExtended strand (participates in β ladder)trans-105.4125.1169.7178.2161.1178.344.30109.2E522 Y523 F526 I569 V570 W571 D589E522-K587 WeakPolarHBondContact OE1-CE 3.2Å; E522-K587 IonicContact OE1-NZ 3.31Å; E522-K587 PolarHBondContact OE1-NZ 2.67Å; Y523-K587 HydrophobicContact CD1-CD 3.93Å; Y523-K587 HydrophobicContact CE1-CD 3.83Å; Y523-K587 HydrophobicContact CE1-CG 4.46Å; F526-K587 HydrophobicContact CB-CD 4.39Å; F526-K587 HydrophobicContact CD1-CB 3.93Å; F526-K587 HydrophobicContact CD1-CD 4.22Å; F526-K587 HydrophobicContact CD2-CB 4.18Å; F526-K587 HydrophobicContact CE1-CB 3.56Å; F526-K587 HydrophobicContact CE2-CB 3.84Å; F526-K587 HydrophobicContact CG-CB 4.22Å; F526-K587 HydrophobicContact CG-CD 4.14Å; F526-K587 HydrophobicContact CZ-CB 3.51Å; I569-K587 PolarHBondContact O-N 3.38Å; V570-K587 WeakPolarHBondContact CA-O 3.37Å; V570-K587 HydrophobicContact CG2-CB 4.49Å; W571-K587 PolarHBondContact N-O 3.33Å; K587-D589 WeakPolarHBondContact CE-OD2 3.33Å; K587-D589 IonicContact NZ-OD1 2.73Å; K587-D589 PolarHBondContact NZ-OD1 3.09Å; K587-D589 IonicContact NZ-OD2 2.73Å; K587-D589 PolarHBondContact NZ-OD2 3.39Å
588I95.8Very high92.8Very high31 Ų3144.8 Ų44.816%0.15927%0.27CS..EExtended strand (participates in β ladder)trans-122120.6-174-51.2-178.6000108.1W571 F573 V580 L586W571-I588 WeakPolarHBondContact O-CA 3.38Å; F573-I588 HydrophobicContact CB-CG2 3.81Å; F573-I588 HydrophobicContact CD1-CG2 4.09Å; F573-I588 HydrophobicContact CG-CG2 4.39Å; V580-I588 HydrophobicContact CB-CD1 3.87Å; V580-I588 HydrophobicContact CG2-CD1 3.48Å; V580-I588 VanDerWaalsContact CG2-CD1 3.48Å; L586-I588 HydrophobicContact CD1-CG1 4.37Å; L586-I588 HydrophobicContact CD2-CD1 3.69Å; L586-I588 HydrophobicContact CD2-CG1 3.95Å; L586-I588 HydrophobicContact CG-CD1 4.02Å; L586-I588 HydrophobicContact CG-CG1 3.7Å
589D94.7Very high93.1Very high35 Ų3544.7 Ų44.719%0.18726%0.26CS..EExtended strand (participates in β ladder)trans-137.5148.9174.1-63-55.5000109.5Y523 W571 Q572 F573 K587 W591 I592Y523-D589 VanDerWaalsContact CZ-OD2 3.27Å; Y523-D589 PolarHBondContact OH-OD2 3.42Å; W571-D589 PolarHBondContact O-N 3.09Å; Q572-D589 CarbonylContact C-O 3.46Å; Q572-D589 VanDerWaalsContact CA-O 3.29Å; Q572-D589 WeakPolarHBondContact CA-O 3.3Å; F573-D589 PolarHBondContact N-O 2.83Å; K587-D589 WeakPolarHBondContact CE-OD2 3.33Å; K587-D589 IonicContact NZ-OD1 2.73Å; K587-D589 PolarHBondContact NZ-OD1 3.09Å; K587-D589 IonicContact NZ-OD2 2.73Å; K587-D589 PolarHBondContact NZ-OD2 3.39Å; D589-W591 PolarHBondContact O-N 3.34Å; D589-I592 HydrophobicContact CB-CG2 4.05Å
590P93.6Very high93.6Very high94 Ų9442.9 Ų42.961%0.6125%0.251SS*.SBendtrans-64.9-27.317626.1-34.3000112.4Q572 F573 N574Q572-P590 WeakPolarHBondContact CG-O 3.39Å; F573-P590 WeakPolarHBondContact O-CA 3.49Å; N574-P590 HydrophobicContact CB-CB 4.44Å
591W94.7Very high93.8Very high164 Ų16448.1 Ų48.162%0.62129%0.287SS*.SBendtrans-143.7132.7176.1-166.7-103000110.3H542 Q572 D589H542-W591 HydrophobicContact CB-CH2 4.3Å; H542-W591 HydrophobicContact CB-CZ3 4.06Å; Q572-W591 VanDerWaalsContact NE2-CE3 3.29Å; Q572-W591 VanDerWaalsContact NE2-CZ3 3.31Å; D589-W591 PolarHBondContact O-N 3.34Å
592I96Very high94.3Very high2 Ų249 Ų491%0.0128%0.284CS..  trans-117.2153-175.566.2174.9000110.6V537 V570 Q572 D589 L594 L597V537-I592 HydrophobicContact CG1-CD1 3.67Å; V570-I592 HydrophobicContact CG1-CB 4.3Å; V570-I592 HydrophobicContact CG1-CD1 4.11Å; V570-I592 HydrophobicContact CG1-CG2 3.82Å; Q572-I592 HydrophobicContact CB-CD1 3.99Å; Q572-I592 HydrophobicContact CB-CG1 4.03Å; Q572-I592 HydrophobicContact CB-CG2 4.13Å; Q572-I592 HydrophobicContact CG-CG1 4.5Å; D589-I592 HydrophobicContact CB-CG2 4.05Å; I592-L594 HydrophobicContact CD1-CB 4.46Å; I592-L594 HydrophobicContact CD1-CD1 4.24Å; I592-L594 HydrophobicContact CG1-CB 4.15Å; I592-L594 PolarHBondContact O-N 3.39Å; I592-L597 HydrophobicContact CB-CD1 3.98Å; I592-L597 HydrophobicContact CD1-CD1 3.88Å; I592-L597 HydrophobicContact CG1-CD1 4.17Å
593P96Very high95.1Very high46 Ų4645.2 Ų45.230%0.29925%0.245SC..  trans-75.564.2173.732.8-35.6000110.7L519 Y523 A596 L597L519-P593 HydrophobicContact CD2-CG 4.01Å; Y523-P593 HydrophobicContact CD1-CG 4.37Å; Y523-P593 HydrophobicContact CD2-CG 3.66Å; Y523-P593 HydrophobicContact CE1-CG 4.32Å; Y523-P593 HydrophobicContact CE2-CG 3.61Å; Y523-P593 HydrophobicContact CG-CG 4.06Å; Y523-P593 WeakPolarHBondContact OH-CD 3.39Å; P593-A596 HydrophobicContact CB-CB 4.41Å; P593-A596 PolarHBondContact O-N 2.87Å; P593-A596 VanDerWaalsContact O-N 3.1Å; P593-L597 HydrophobicContact CG-CD1 4.27Å; P593-L597 HydrophobicContact CG-CG 4.3Å; P593-L597 PolarHBondContact O-N 2.88Å
594L95.8Very high95.6Very high17 Ų1745.9 Ų45.99%0.08925%0.249CC..Hα-helixtrans-51.7-48.2-169.4177.765.8000113.7V537 I592 A596 L597 L598 F606V537-L594 HydrophobicContact CG1-CD1 3.58Å; I592-L594 HydrophobicContact CD1-CB 4.46Å; I592-L594 HydrophobicContact CD1-CD1 4.24Å; I592-L594 HydrophobicContact CG1-CB 4.15Å; I592-L594 PolarHBondContact O-N 3.39Å; L594-A596 VanDerWaalsContact C-N 3.31Å; L594-A596 PolarHBondContact O-N 2.75Å; L594-L597 PolarHBondContact O-N 3.21Å; L594-L598 HydrophobicContact CD1-CD1 3.9Å; L594-L598 HydrophobicContact CD1-CD2 4.25Å; L594-L598 HydrophobicContact CD1-CG 3.82Å; L594-L598 HydrophobicContact CG-CD1 3.92Å; L594-L598 HydrophobicContact CG-CG 4.24Å; L594-L598 WeakPolarHBondContact O-CG 3.26Å; L594-L598 PolarHBondContact O-N 3.08Å; L594-F606 HydrophobicContact CD1-CD2 4.34Å; L594-F606 HydrophobicContact CD1-CE2 3.75Å; L594-F606 HydrophobicContact CD1-CZ 4.09Å; L594-F606 HydrophobicContact CD2-CE2 4.46Å; L594-F606 HydrophobicContact CD2-CZ 4.07Å
595P95.1Very high96.1Very high37 Ų3740.4 Ų40.424%0.2421%0.214CC..Hα-helixtrans-62.3-37.5-178.9-23.335.3000113V516 L598 Q599 F621V516-P595 HydrophobicContact CB-CB 4.42Å; V516-P595 HydrophobicContact CG1-CB 4.05Å; V516-P595 HydrophobicContact CG2-CB 3.53Å; P595-L598 PolarHBondContact O-N 3.01Å; P595-Q599 WeakPolarHBondContact O-CB 3.47Å; P595-Q599 PolarHBondContact O-N 3.49Å; P595-F621 WeakPolarHBondContact O-CE2 3.47Å
596A96.7Very high96.4Very high9 Ų939.8 Ų39.87%0.07421%0.211CC..Hα-helixtrans-71.7-37.4178.400000111.2V516 L519 P593 L594 Q599 H600V516-A596 HydrophobicContact CG1-CB 3.8Å; L519-A596 HydrophobicContact CD2-CB 3.58Å; L519-A596 HydrophobicContact CG-CB 4.16Å; P593-A596 HydrophobicContact CB-CB 4.41Å; P593-A596 PolarHBondContact O-N 2.87Å; P593-A596 VanDerWaalsContact O-N 3.1Å; L594-A596 VanDerWaalsContact C-N 3.31Å; L594-A596 PolarHBondContact O-N 2.75Å; A596-Q599 PolarHBondContact O-N 3.19Å; A596-H600 PolarHBondContact O-N 3.13Å
597L97.9Very high96.5Very high0 Ų038.9 Ų38.90%021%0.206CC..Hα-helixtrans-63.9-45.5173.6-72.6166.2000111.1L519 Y523 V527 V537 V570 I592 P593 L594 Q599 H600 T603L519-L597 HydrophobicContact CD1-CD2 4.12Å; L519-L597 HydrophobicContact CD2-CD2 3.8Å; L519-L597 HydrophobicContact CD2-CG 3.85Å; Y523-L597 HydrophobicContact CD1-CD1 4.5Å; Y523-L597 HydrophobicContact CD1-CD2 4.15Å; Y523-L597 HydrophobicContact CE1-CD1 4.49Å; V527-L597 HydrophobicContact CG2-CD2 3.88Å; V537-L597 HydrophobicContact CG2-CB 4.01Å; V570-L597 HydrophobicContact CB-CD1 4.41Å; V570-L597 HydrophobicContact CG1-CD1 3.78Å; V570-L597 HydrophobicContact CG2-CD2 4.31Å; I592-L597 HydrophobicContact CB-CD1 3.98Å; I592-L597 HydrophobicContact CD1-CD1 3.88Å; I592-L597 HydrophobicContact CG1-CD1 4.17Å; P593-L597 HydrophobicContact CG-CD1 4.27Å; P593-L597 HydrophobicContact CG-CG 4.3Å; P593-L597 PolarHBondContact O-N 2.88Å; L594-L597 PolarHBondContact O-N 3.21Å; L597-Q599 PolarHBondContact O-N 3.38Å; L597-H600 WeakPolarHBondContact O-CB 3.42Å; L597-H600 PolarHBondContact O-N 2.99Å; L597-T603 WeakPolarHBondContact O-CB 3.29Å; L597-T603 PolarHBondContact O-OG1 2.9Å
598L97.5Very high96.6Very high2 Ų237.8 Ų37.81%0.0120%0.201CC..Hα-helixtrans-65.9-36.3178.9-68.2177.1000112.5L594 P595 H600 T603 F606 E617 A618 F621 V623L594-L598 HydrophobicContact CD1-CD1 3.9Å; L594-L598 HydrophobicContact CD1-CD2 4.25Å; L594-L598 HydrophobicContact CD1-CG 3.82Å; L594-L598 HydrophobicContact CG-CD1 3.92Å; L594-L598 HydrophobicContact CG-CG 4.24Å; L594-L598 WeakPolarHBondContact O-CG 3.26Å; L594-L598 PolarHBondContact O-N 3.08Å; P595-L598 PolarHBondContact O-N 3.01Å; L598-H600 VanDerWaalsContact C-N 3.26Å; L598-H600 PolarHBondContact O-N 2.96Å; L598-T603 HydrophobicContact CD2-CG2 4.34Å; L598-F606 HydrophobicContact CD1-CE1 4.5Å; L598-F606 HydrophobicContact CD2-CB 3.84Å; L598-F606 HydrophobicContact CD2-CD1 4.17Å; L598-F606 HydrophobicContact CD2-CD2 4.07Å; L598-F606 HydrophobicContact CD2-CG 3.78Å; L598-E617 HydrophobicContact CD1-CB 3.8Å; L598-A618 HydrophobicContact CD1-CB 4.27Å; L598-F621 HydrophobicContact CB-CB 4.46Å; L598-F621 HydrophobicContact CB-CD2 3.68Å; L598-F621 HydrophobicContact CB-CE2 4.42Å; L598-F621 HydrophobicContact CB-CG 4.47Å; L598-F621 VanDerWaalsContact O-CB 3.27Å; L598-F621 WeakPolarHBondContact O-CB 3.3Å; L598-V623 HydrophobicContact CD2-CB 4.34Å; L598-V623 HydrophobicContact CD2-CG1 4.31Å; L598-V623 HydrophobicContact CD2-CG2 4.25Å; L598-V623 WeakPolarHBondContact O-CG2 3.32Å
599Q95.8Very high96.6Very high83 Ų8337.2 Ų37.239%0.38820%0.198SC..Hα-helixtrans-66.4-28175.5-172.9-178.321.900112.7V516 P595 A596 L597 F621V516-Q599 PolarHBondContact O-OE1 3.38Å; P595-Q599 WeakPolarHBondContact O-CB 3.47Å; P595-Q599 PolarHBondContact O-N 3.49Å; A596-Q599 PolarHBondContact O-N 3.19Å; L597-Q599 PolarHBondContact O-N 3.38Å; Q599-F621 HydrophobicContact CB-CD1 3.86Å; Q599-F621 HydrophobicContact CB-CD2 4.22Å; Q599-F621 HydrophobicContact CB-CE1 3.73Å; Q599-F621 HydrophobicContact CB-CE2 4.08Å; Q599-F621 HydrophobicContact CB-CG 4.11Å; Q599-F621 HydrophobicContact CB-CZ 3.83Å; Q599-F621 HydrophobicContact CG-CD1 3.91Å; Q599-F621 HydrophobicContact CG-CE1 3.65Å; Q599-F621 HydrophobicContact CG-CZ 4.15Å
600H97.1Very high96.6Very high32 Ų3235.6 Ų35.615%0.14819%0.189CC..SBendtrans-65.9133.8-174.2-162.9-85.6000112.3L519 V527 E528 A596 L597 L598 K602 T603L519-H600 HydrophobicContact CD1-CB 4.15Å; V527-H600 VanDerWaalsContact CG1-ND1 3.31Å; V527-H600 WeakPolarHBondContact CG1-ND1 3.01Å; E528-H600 IonicContact OE1-CE1 3.46Å; E528-H600 IonicContact OE1-NE2 3.39Å; E528-H600 PolarHBondContact OE1-NE2 3.15Å; A596-H600 PolarHBondContact O-N 3.13Å; L597-H600 WeakPolarHBondContact O-CB 3.42Å; L597-H600 PolarHBondContact O-N 2.99Å; L598-H600 VanDerWaalsContact C-N 3.26Å; L598-H600 PolarHBondContact O-N 2.96Å; H600-K602 WeakPolarHBondContact ND1-CB 3.41Å; H600-K602 PolarHBondContact ND1-N 3.04Å; H600-K602 PolarHBondContact O-N 3.3Å; H600-K602 VanDerWaalsContact O-N 3.12Å; H600-T603 WeakPolarHBondContact O-CB 3.16Å; H600-T603 PolarHBondContact O-N 3.19Å
601S95.2Very high96.5Very high111 Ų11131.6 Ų31.678%0.77617%0.165SC*.THydrogen-bonded Turntrans-61.6-26.2-173.862.60000114.5T603S601-T603 VanDerWaalsContact C-N 3.32Å
602K97.1Very high96.2Very high76 Ų7626.2 Ų26.233%0.3315%0.148SC..THydrogen-bonded Turntrans-75.9-14175.4-68.5-75.4-172165.20113.8V527 G534 T535 H600 I604V527-K602 HydrophobicContact CG1-CB 3.72Å; V527-K602 HydrophobicContact CG1-CG 4.39Å; G534-K602 CarbonylContact C-O 3.49Å; G534-K602 WeakPolarHBondContact CA-O 3.5Å; T535-K602 PolarHBondContact N-O 3.42Å; H600-K602 WeakPolarHBondContact ND1-CB 3.41Å; H600-K602 PolarHBondContact ND1-N 3.04Å; H600-K602 PolarHBondContact O-N 3.3Å; H600-K602 VanDerWaalsContact O-N 3.12Å; K602-I604 PolarHBondContact O-N 3.02Å
603T98.3Very high95.9Very high2 Ų232.6 Ų32.61%0.01218%0.176CC..EExtended strand (participates in β ladder)trans-78.5116.7179.1-62.60000110.5T535 V537 L597 L598 H600 S601 V623T535-T603 WeakPolarHBondContact O-CA 3.11Å; V537-T603 HydrophobicContact CG2-CG2 3.75Å; L597-T603 WeakPolarHBondContact O-CB 3.29Å; L597-T603 PolarHBondContact O-OG1 2.9Å; L598-T603 HydrophobicContact CD2-CG2 4.34Å; H600-T603 WeakPolarHBondContact O-CB 3.16Å; H600-T603 PolarHBondContact O-N 3.19Å; S601-T603 VanDerWaalsContact C-N 3.32Å; T603-V623 HydrophobicContact CG2-CG1 3.93Å; T603-V623 HydrophobicContact CG2-CG2 4.21Å
604I98.1Very high95.7Very high53 Ų5331 Ų3127%0.27217%0.166SC..EExtended strand (participates in β ladder)trans-117.4-17-169.757.5169.9000113.7T535 Y567 K602 L668T535-I604 WeakPolarHBondContact O-CG1 2.71Å; T535-I604 PolarHBondContact O-N 3.48Å; Y567-I604 HydrophobicContact CD1-CD1 3.62Å; Y567-I604 HydrophobicContact CE1-CD1 3.33Å; K602-I604 PolarHBondContact O-N 3.02Å; I604-L668 HydrophobicContact CD1-CD2 3.46Å; I604-L668 VanDerWaalsContact CD1-CD2 3.46Å; I604-L668 HydrophobicContact CG1-CD2 3.94Å
605L98.7Very high95.6Very high0 Ų030.2 Ų30.20%016%0.162CC..EExtended strand (participates in β ladder)trans-147.2133.4178177.461.7000110I536 V537 I607 L626 M664 V667 L668I536-L605 WeakPolarHBondContact CA-O 3.49Å; I536-L605 HydrophobicContact CD1-CD2 4.38Å; I536-L605 HydrophobicContact CG1-CB 4.23Å; I536-L605 HydrophobicContact CG1-CD2 4.41Å; I536-L605 HydrophobicContact CG2-CB 4.24Å; I536-L605 HydrophobicContact CG2-CD2 4.03Å; I536-L605 HydrophobicContact CG2-CG 4.16Å; V537-L605 PolarHBondContact N-O 3.27Å; L605-I607 HydrophobicContact CD2-CD1 4.43Å; L605-I607 HydrophobicContact CD2-CG1 4.22Å; L605-I607 HydrophobicContact CG-CG1 4.16Å; L605-L626 HydrophobicContact CD1-CB 4.32Å; L605-M664 HydrophobicContact CD2-CB 4.23Å; L605-M664 HydrophobicContact CD2-CG 4.11Å; L605-V667 HydrophobicContact CD1-CB 4.16Å; L605-V667 HydrophobicContact CD1-CG1 3.69Å; L605-L668 HydrophobicContact CB-CD2 4.11Å; L605-L668 HydrophobicContact CD2-CD2 4.31Å; L605-L668 HydrophobicContact CD2-CG 4.24Å
606F98.8Very high95.4Very high0 Ų028.8 Ų28.80%015%0.151CC..EExtended strand (participates in β ladder)trans-113.9116.1171178.3-140.4000110.5V537 L594 L598 T608 A618 V623 P624 M625 L626V537-F606 HydrophobicContact CB-CD2 4.18Å; V537-F606 HydrophobicContact CG1-CD2 4.13Å; V537-F606 HydrophobicContact CG1-CE2 4.33Å; V537-F606 CarbonylContact O-C 3.48Å; V537-F606 WeakPolarHBondContact O-CA 3.19Å; V537-F606 WeakPolarHBondContact O-CD2 3.27Å; L594-F606 HydrophobicContact CD1-CD2 4.34Å; L594-F606 HydrophobicContact CD1-CE2 3.75Å; L594-F606 HydrophobicContact CD1-CZ 4.09Å; L594-F606 HydrophobicContact CD2-CE2 4.46Å; L594-F606 HydrophobicContact CD2-CZ 4.07Å; L598-F606 HydrophobicContact CD1-CE1 4.5Å; L598-F606 HydrophobicContact CD2-CB 3.84Å; L598-F606 HydrophobicContact CD2-CD1 4.17Å; L598-F606 HydrophobicContact CD2-CD2 4.07Å; L598-F606 HydrophobicContact CD2-CG 3.78Å; F606-T608 HydrophobicContact CD1-CG2 3.96Å; F606-T608 VanDerWaalsContact CE1-CB 3.43Å; F606-T608 HydrophobicContact CE1-CG2 3.85Å; F606-T608 VanDerWaalsContact CZ-CB 3.45Å; F606-T608 HydrophobicContact CZ-CG2 4.37Å; F606-T608 WeakPolarHBondContact CZ-OG1 3.32Å; F606-A618 HydrophobicContact CD1-CB 3.59Å; F606-A618 HydrophobicContact CE1-CB 4.23Å; F606-A618 HydrophobicContact CG-CB 4.47Å; F606-V623 HydrophobicContact CB-CG1 3.78Å; F606-P624 PolarHBondContact N-O 3.49Å; F606-M625 HydrophobicContact CB-CG 4.01Å; F606-M625 HydrophobicContact CD1-CG 3.82Å; F606-M625 HydrophobicContact CD1-SD 3.91Å; F606-M625 HydrophobicContact CE1-SD 4.48Å; F606-M625 HydrophobicContact CG-CG 4.32Å; F606-M625 CarbonylContact O-C 3.38Å; F606-M625 WeakPolarHBondContact O-CA 3.36Å; F606-L626 PolarHBondContact O-N 3.1Å
607I98.6Very high95.2Very high0 Ų028.9 Ų28.90%015%0.15CC..EExtended strand (participates in β ladder)trans-94.5123.2173.9-47.1-179000107.8I536 V537 F538 S539 F561 L605 L626 I628 F660 M664I536-I607 HydrophobicContact CG2-CD1 3.7Å; I536-I607 HydrophobicContact CG2-CG1 3.9Å; V537-I607 PolarHBondContact O-N 3Å; F538-I607 WeakPolarHBondContact CA-O 3.5Å; F538-I607 HydrophobicContact CB-CB 4.24Å; F538-I607 HydrophobicContact CD2-CB 3.44Å; F538-I607 VanDerWaalsContact CD2-CB 3.44Å; F538-I607 HydrophobicContact CD2-CG2 3.38Å; F538-I607 WeakPolarHBondContact CD2-O 3.42Å; F538-I607 HydrophobicContact CE2-CB 3.97Å; F538-I607 HydrophobicContact CE2-CG2 3.33Å; F538-I607 HydrophobicContact CG-CB 4.09Å; F538-I607 HydrophobicContact CG-CG2 4.31Å; F538-I607 HydrophobicContact CZ-CG2 4.3Å; S539-I607 PolarHBondContact N-O 3.41Å; F561-I607 HydrophobicContact CE1-CD1 3.9Å; F561-I607 HydrophobicContact CZ-CD1 4.2Å; L605-I607 HydrophobicContact CD2-CD1 4.43Å; L605-I607 HydrophobicContact CD2-CG1 4.22Å; L605-I607 HydrophobicContact CG-CG1 4.16Å; I607-L626 CarbonylContact C-O 3.58Å; I607-L626 VanDerWaalsContact CA-O 3.28Å; I607-L626 WeakPolarHBondContact CA-O 3.37Å; I607-L626 HydrophobicContact CB-CB 4.49Å; I607-L626 HydrophobicContact CD1-CD2 4.3Å; I607-L626 HydrophobicContact CG1-CB 4.17Å; I607-L626 HydrophobicContact CG1-CD2 4.37Å; I607-L626 HydrophobicContact CG2-CB 4.24Å; I607-L626 HydrophobicContact CG2-CD2 4.25Å; I607-L626 HydrophobicContact CG2-CG 4.37Å; I607-I628 HydrophobicContact CG2-CD1 4.44Å; I607-F660 HydrophobicContact CD1-CE1 4.43Å; I607-F660 HydrophobicContact CD1-CE2 4.18Å; I607-F660 HydrophobicContact CD1-CZ 3.61Å; I607-F660 HydrophobicContact CG2-CE2 3.95Å; I607-F660 HydrophobicContact CG2-CZ 4.05Å; I607-M664 HydrophobicContact CD1-CG 3.99Å; I607-M664 HydrophobicContact CD1-SD 3.6Å; I607-M664 VanDerWaalsContact CD1-SD 3.6Å
608T97.7Very high95.1Very high0 Ų028.9 Ų28.90%015%0.15CC..EExtended strand (participates in β ladder)trans-146.8163.8-167.5-174.90000112.5F540 F606 S610 M625 L626 S627 I628F540-T608 VanDerWaalsContact CE2-C 3.42Å; F606-T608 HydrophobicContact CD1-CG2 3.96Å; F606-T608 VanDerWaalsContact CE1-CB 3.43Å; F606-T608 HydrophobicContact CE1-CG2 3.85Å; F606-T608 VanDerWaalsContact CZ-CB 3.45Å; F606-T608 HydrophobicContact CZ-CG2 4.37Å; F606-T608 WeakPolarHBondContact CZ-OG1 3.32Å; T608-S610 PolarHBondContact OG1-N 2.96Å; T608-M625 HydrophobicContact CG2-CB 4.47Å; T608-M625 HydrophobicContact CG2-CG 4.15Å; T608-M625 HydrophobicContact CG2-SD 3.84Å; T608-L626 PolarHBondContact N-O 3.49Å; T608-S627 CarbonylContact O-C 2.98Å; T608-S627 WeakPolarHBondContact O-CA 3.4Å; T608-I628 PolarHBondContact O-N 2.69Å
609H96Very high95Very high19 Ų1928.8 Ų28.89%0.08815%0.15CC..  trans-85.11.9165.469-58000112.4F540 G611 I628 L630 Q634F540-H609 VanDerWaalsContact C-ND1 3.31Å; F540-H609 VanDerWaalsContact CA-ND1 3.34Å; F540-H609 WeakPolarHBondContact CA-ND1 3.37Å; F540-H609 HydrophobicContact CB-CB 4.34Å; F540-H609 HydrophobicContact CD1-CB 4.35Å; F540-H609 HydrophobicContact CD2-CB 4.08Å; F540-H609 HydrophobicContact CE2-CB 4.44Å; F540-H609 HydrophobicContact CG-CB 4.03Å; F540-H609 PolarHBondContact O-CE1 3.42Å; F540-H609 PolarHBondContact O-ND1 3.02Å; F540-H609 PolarHBondContact O-NE2 3.34Å; H609-G611 WeakPolarHBondContact NE2-CA 3.43Å; H609-G611 PolarHBondContact NE2-N 2.92Å; H609-I628 WeakPolarHBondContact CA-O 3.32Å; H609-L630 HydrophobicContact CB-CD1 4.37Å; H609-L630 HydrophobicContact CB-CG 4.17Å; H609-Q634 PolarHBondContact CD2-NE2 3.28Å; H609-Q634 VanDerWaalsContact O-CB 3.25Å; H609-Q634 WeakPolarHBondContact O-CB 3.48Å; H609-Q634 WeakPolarHBondContact O-CG 3.34Å
610S94.2Very high94.8Very high0 Ų025.4 Ų25.40%014%0.135CC..  trans62.236.4-173.5-69.40000114.6T608 I612 S627 I637 T638T608-S610 PolarHBondContact OG1-N 2.96Å; S610-I612 PolarHBondContact O-N 3.12Å; S610-S627 WeakPolarHBondContact CB-OG 3.26Å; S610-S627 VanDerWaalsContact OG-CB 3.24Å; S610-S627 WeakPolarHBondContact OG-CB 3.01Å; S610-S627 PolarHBondContact OG-OG 3.21Å; S610-I637 WeakPolarHBondContact O-CD1 3.37Å; S610-T638 WeakPolarHBondContact CB-OG1 3.47Å; S610-T638 PolarHBondContact OG-OG1 3.27Å
611G92.1Very high94.8Very high11 Ų1125.7 Ų25.711%0.11314%0.136CC..  trans-59.5131.5166.100000111.2H609 K613 S614 F615H609-G611 WeakPolarHBondContact NE2-CA 3.43Å; H609-G611 PolarHBondContact NE2-N 2.92Å; G611-K613 VanDerWaalsContact C-N 3.27Å; G611-K613 PolarHBondContact O-N 3.42Å; G611-K613 VanDerWaalsContact O-N 3.07Å; G611-S614 PolarHBondContact O-N 3.47Å; G611-S614 PolarHBondContact O-OG 2.93Å; G611-S614 VanDerWaalsContact O-OG 3.05Å; G611-F615 WeakPolarHBondContact O-CB 3.42Å; G611-F615 PolarHBondContact O-N 3.08Å
612I88.5Confident94.9Very high51 Ų5121 Ų2126%0.26210%0.103SC..Hα-helixtrans-48.7-42.1-168.1-171.2131.8000114.4G490 M492 S610 R616 I637G490-I612 WeakPolarHBondContact O-CD1 3.46Å; M492-I612 HydrophobicContact CE-CB 4.17Å; M492-I612 HydrophobicContact CE-CD1 3.35Å; M492-I612 HydrophobicContact CE-CG1 3.37Å; M492-I612 HydrophobicContact CG-CD1 4.34Å; S610-I612 PolarHBondContact O-N 3.12Å; I612-R616 VanDerWaalsContact O-CG 3.23Å; I612-R616 WeakPolarHBondContact O-CG 3.45Å; I612-R616 PolarHBondContact O-N 3.41Å; I612-I637 HydrophobicContact CB-CD1 3.95Å; I612-I637 HydrophobicContact CD1-CD1 4.14Å; I612-I637 HydrophobicContact CG1-CD1 4.43Å
613K88.8Confident94.9Very high136 Ų13617.4 Ų17.459%0.5919%0.088SC*.Hα-helixtrans-66.4-57.9-179-173.9-177.7177.1-174.90112.2Y511 G611 F615 R616 E617Y511-K613 WeakPolarHBondContact OH-CA 3.34Å; Y511-K613 PolarHBondContact OH-O 3.23Å; G611-K613 VanDerWaalsContact C-N 3.27Å; G611-K613 PolarHBondContact O-N 3.42Å; G611-K613 VanDerWaalsContact O-N 3.07Å; K613-F615 VanDerWaalsContact C-N 3.28Å; K613-F615 PolarHBondContact O-N 3.23Å; K613-R616 PolarHBondContact O-N 2.77Å; K613-E617 VanDerWaalsContact CE-OE1 3.24Å; K613-E617 WeakPolarHBondContact CE-OE1 3.04Å; K613-E617 WeakPolarHBondContact O-CG 3.11Å; K613-E617 PolarHBondContact O-N 2.99Å
614S92.3Very high94.9Very high12 Ų1217.4 Ų17.48%0.0849%0.088CC..Hα-helixtrans-64.2-33.2-17962.50000112.9G611 R616 E617 A618G611-S614 PolarHBondContact O-N 3.47Å; G611-S614 PolarHBondContact O-OG 2.93Å; G611-S614 VanDerWaalsContact O-OG 3.05Å; S614-R616 VanDerWaalsContact C-N 3.34Å; S614-R616 PolarHBondContact O-N 3.49Å; S614-E617 PolarHBondContact O-N 3.35Å; S614-A618 WeakPolarHBondContact O-CB 3.35Å; S614-A618 PolarHBondContact O-N 2.72Å
615F93.6Very high95Very high1 Ų114.9 Ų14.90%0.0048%0.075CC..Hα-helixtrans-58.8-47.9174.3-179.5-96000111.2M492 L496 G611 K613 A618 V619 M625 I637 M641 F646M492-F615 HydrophobicContact CE-CD1 3.73Å; M492-F615 HydrophobicContact CE-CE1 4.21Å; M492-F615 HydrophobicContact SD-CD1 3.92Å; M492-F615 HydrophobicContact SD-CE1 3.77Å; L496-F615 HydrophobicContact CD1-CD1 4.5Å; L496-F615 HydrophobicContact CD1-CE1 3.78Å; G611-F615 WeakPolarHBondContact O-CB 3.42Å; G611-F615 PolarHBondContact O-N 3.08Å; K613-F615 VanDerWaalsContact C-N 3.28Å; K613-F615 PolarHBondContact O-N 3.23Å; F615-A618 PolarHBondContact O-N 2.94Å; F615-V619 HydrophobicContact CD1-CG2 4.39Å; F615-V619 HydrophobicContact CE1-CG2 4.12Å; F615-V619 HydrophobicContact CZ-CG2 4.43Å; F615-V619 WeakPolarHBondContact O-CG2 3.14Å; F615-V619 PolarHBondContact O-N 3.46Å; F615-M625 HydrophobicContact CD2-CE 3.57Å; F615-M625 HydrophobicContact CD2-SD 3.59Å; F615-M625 VanDerWaalsContact CD2-SD 3.59Å; F615-M625 HydrophobicContact CE2-CE 3.49Å; F615-M625 VanDerWaalsContact CE2-CE 3.49Å; F615-M625 HydrophobicContact CE2-SD 4Å; F615-M625 HydrophobicContact CG-CE 4.33Å; F615-M625 HydrophobicContact CG-SD 4.44Å; F615-M625 HydrophobicContact CZ-CE 4.22Å; F615-I637 HydrophobicContact CB-CG2 4.14Å; F615-I637 HydrophobicContact CD1-CG2 3.65Å; F615-I637 HydrophobicContact CD2-CG2 3.47Å; F615-I637 VanDerWaalsContact CD2-CG2 3.47Å; F615-I637 HydrophobicContact CE1-CG2 3.77Å; F615-I637 HydrophobicContact CE2-CG2 3.61Å; F615-I637 HydrophobicContact CG-CG2 3.46Å; F615-I637 VanDerWaalsContact CG-CG2 3.46Å; F615-I637 HydrophobicContact CZ-CG2 3.74Å; F615-M641 HydrophobicContact CE2-CB 3.75Å; F615-M641 HydrophobicContact CE2-CG 4.31Å; F615-M641 HydrophobicContact CE2-SD 4.4Å; F615-M641 HydrophobicContact CZ-CB 3.96Å; F615-F646 HydrophobicContact CE1-CZ 4.4Å; F615-F646 AromaticContact CE2-CE2 3.98Å; F615-F646 HydrophobicContact CE2-CE2 3.98Å; F615-F646 HydrophobicContact CE2-CZ 4.33Å; F615-F646 AromaticContact CZ-CE2 3.77Å; F615-F646 HydrophobicContact CZ-CE2 3.77Å; F615-F646 AromaticContact CZ-CZ 3.66Å; F615-F646 HydrophobicContact CZ-CZ 3.66Å
616R90.3Very high95Very high7 Ų714.9 Ų14.93%0.0268%0.075CC..Hα-helixtrans-67.3-40.3178.5-69.8173.966.3100.243.4112.1S491 M492 P493 D510 Y511 I612 K613 S614 A618 V619 C620S491-R616 PolarHBondContact O-NH1 2.93Å; M492-R616 HydrophobicContact CE-CG 4.28Å; P493-R616 VanDerWaalsContact CD-CZ 3.49Å; P493-R616 VanDerWaalsContact CD-NH1 3.3Å; D510-R616 IonicContact OD1-CZ 3.1Å; D510-R616 IonicContact OD1-NE 2.76Å; D510-R616 IonicContact OD1-NH1 3.99Å; D510-R616 IonicContact OD1-NH2 3.35Å; D510-R616 PolarHBondContact OD1-NH2 3.47Å; D510-R616 IonicContact OD2-CZ 2.66Å; D510-R616 IonicContact OD2-NH1 3.82Å; D510-R616 PolarHBondContact OD2-NH1 3.41Å; D510-R616 IonicContact OD2-NH2 3.64Å; D510-R616 PolarHBondContact OD2-NH2 3.01Å; Y511-R616 VanDerWaalsContact OH-CB 3.32Å; Y511-R616 WeakPolarHBondContact OH-CB 2.99Å; Y511-R616 WeakPolarHBondContact OH-CD 3.46Å; I612-R616 VanDerWaalsContact O-CG 3.23Å; I612-R616 WeakPolarHBondContact O-CG 3.45Å; I612-R616 PolarHBondContact O-N 3.41Å; K613-R616 PolarHBondContact O-N 2.77Å; S614-R616 VanDerWaalsContact C-N 3.34Å; S614-R616 PolarHBondContact O-N 3.49Å; R616-A618 VanDerWaalsContact C-N 3.28Å; R616-A618 PolarHBondContact O-N 2.78Å; R616-V619 PolarHBondContact O-N 3.45Å; R616-C620 WeakPolarHBondContact O-CB 3.12Å; R616-C620 PolarHBondContact O-N 3.21Å; R616-C620 PolarHBondContact O-SG 3.42Å
617E92.9Very high94.9Very high11 Ų1114.9 Ų14.95%0.0518%0.075CC..Hα-helixtrans-57.2-43.9173.5-68.4168.9175.500111P514 L598 K613 S614 V619 C620 F621P514-E617 HydrophobicContact CG-CG 4.09Å; L598-E617 HydrophobicContact CD1-CB 3.8Å; K613-E617 VanDerWaalsContact CE-OE1 3.24Å; K613-E617 WeakPolarHBondContact CE-OE1 3.04Å; K613-E617 WeakPolarHBondContact O-CG 3.11Å; K613-E617 PolarHBondContact O-N 2.99Å; S614-E617 PolarHBondContact O-N 3.35Å; E617-V619 PolarHBondContact O-N 3.37Å; E617-C620 WeakPolarHBondContact O-CB 3.07Å; E617-C620 PolarHBondContact O-N 3.2Å; E617-F621 HydrophobicContact CB-CE2 4.47Å; E617-F621 WeakPolarHBondContact O-CD2 3.37Å; E617-F621 PolarHBondContact O-N 3.41Å
618A95.9Very high94.9Very high0 Ų015.1 Ų15.10%08%0.076CC..Hα-helixtrans-64.6-39.6176.300000112.6L598 F606 S614 F615 R616 F621 A622 V623 M625L598-A618 HydrophobicContact CD1-CB 4.27Å; F606-A618 HydrophobicContact CD1-CB 3.59Å; F606-A618 HydrophobicContact CE1-CB 4.23Å; F606-A618 HydrophobicContact CG-CB 4.47Å; S614-A618 WeakPolarHBondContact O-CB 3.35Å; S614-A618 PolarHBondContact O-N 2.72Å; F615-A618 PolarHBondContact O-N 2.94Å; R616-A618 VanDerWaalsContact C-N 3.28Å; R616-A618 PolarHBondContact O-N 2.78Å; A618-F621 CarbonylContact O-C 3.49Å; A618-A622 CarbonylContact O-C 3.53Å; A618-A622 WeakPolarHBondContact O-CA 3.27Å; A618-A622 PolarHBondContact O-N 2.86Å; A618-V623 HydrophobicContact CB-CB 4.45Å; A618-V623 PolarHBondContact O-N 3.37Å; A618-M625 HydrophobicContact CB-CE 3.95Å; A618-M625 HydrophobicContact CB-CG 4.17Å; A618-M625 HydrophobicContact CB-SD 3.75Å
619V94.7Very high94.8Very high0 Ų015.7 Ų15.70%08%0.08CC..Hα-helixtrans-67-44.3173.9-177.30000111.1L496 F615 R616 E617 F621 A622 M625 F646 I677 L680 S681 L684L496-V619 HydrophobicContact CD1-CB 4.21Å; L496-V619 HydrophobicContact CD1-CG1 4.02Å; L496-V619 HydrophobicContact CD1-CG2 3.81Å; L496-V619 HydrophobicContact CD2-CG1 4.27Å; F615-V619 HydrophobicContact CD1-CG2 4.39Å; F615-V619 HydrophobicContact CE1-CG2 4.12Å; F615-V619 HydrophobicContact CZ-CG2 4.43Å; F615-V619 WeakPolarHBondContact O-CG2 3.14Å; F615-V619 PolarHBondContact O-N 3.46Å; R616-V619 PolarHBondContact O-N 3.45Å; E617-V619 PolarHBondContact O-N 3.37Å; V619-F621 VanDerWaalsContact C-N 3.32Å; V619-F621 PolarHBondContact O-N 3.16Å; V619-A622 PolarHBondContact O-N 3.2Å; V619-M625 HydrophobicContact CG2-CE 4.02Å; V619-F646 HydrophobicContact CG2-CE2 3.97Å; V619-F646 HydrophobicContact CG2-CZ 4Å; V619-I677 HydrophobicContact CB-CD1 4.45Å; V619-I677 HydrophobicContact CB-CG1 4.42Å; V619-I677 HydrophobicContact CG1-CG1 4.19Å; V619-I677 HydrophobicContact CG2-CD1 4.14Å; V619-I677 HydrophobicContact CG2-CG1 4.34Å; V619-L680 HydrophobicContact CG1-CB 4.24Å; V619-S681 WeakPolarHBondContact O-CB 3.29Å; V619-L684 HydrophobicContact CB-CD1 4.39Å; V619-L684 HydrophobicContact CG1-CD1 3.5Å
620C93.1Very high94.7Very high12 Ų1216.8 Ų16.88%0.0819%0.086CC..Hα-helixtrans-54.1-47.9175.8-84.90000111.9C513 R616 E617 A622 S681C513-C620 WeakPolarHBondContact CA-SG 3.38Å; C513-C620 HydrophobicContact CB-CB 3.64Å; C513-C620 WeakPolarHBondContact CB-SG 3.4Å; C513-C620 WeakPolarHBondContact SG-CB 3.35Å; C513-C620 CovalentContact SG-SG 2.04Å; C513-C620 PolarHBondContact SG-SG 3.14Å; R616-C620 WeakPolarHBondContact O-CB 3.12Å; R616-C620 PolarHBondContact O-N 3.21Å; R616-C620 PolarHBondContact O-SG 3.42Å; E617-C620 WeakPolarHBondContact O-CB 3.07Å; E617-C620 PolarHBondContact O-N 3.2Å; C620-A622 VanDerWaalsContact C-N 3.26Å; C620-A622 PolarHBondContact O-N 3.09Å; C620-S681 PolarHBondContact O-OG 3.23Å
621F95.9Very high94.6Very high38 Ų3822.1 Ų22.117%0.16711%0.11CC..THydrogen-bonded Turntrans-87.89.9178.7-56.1-54.1000113.8P514 V516 P595 L598 Q599 E617 A618 V619 V623P514-F621 HydrophobicContact CG-CE2 4.01Å; P514-F621 HydrophobicContact CG-CZ 3.86Å; P514-F621 WeakPolarHBondContact O-CZ 3.3Å; V516-F621 HydrophobicContact CG2-CZ 4.04Å; P595-F621 WeakPolarHBondContact O-CE2 3.47Å; L598-F621 HydrophobicContact CB-CB 4.46Å; L598-F621 HydrophobicContact CB-CD2 3.68Å; L598-F621 HydrophobicContact CB-CE2 4.42Å; L598-F621 HydrophobicContact CB-CG 4.47Å; L598-F621 VanDerWaalsContact O-CB 3.27Å; L598-F621 WeakPolarHBondContact O-CB 3.3Å; Q599-F621 HydrophobicContact CB-CD1 3.86Å; Q599-F621 HydrophobicContact CB-CD2 4.22Å; Q599-F621 HydrophobicContact CB-CE1 3.73Å; Q599-F621 HydrophobicContact CB-CE2 4.08Å; Q599-F621 HydrophobicContact CB-CG 4.11Å; Q599-F621 HydrophobicContact CB-CZ 3.83Å; Q599-F621 HydrophobicContact CG-CD1 3.91Å; Q599-F621 HydrophobicContact CG-CE1 3.65Å; Q599-F621 HydrophobicContact CG-CZ 4.15Å; E617-F621 HydrophobicContact CB-CE2 4.47Å; E617-F621 WeakPolarHBondContact O-CD2 3.37Å; E617-F621 PolarHBondContact O-N 3.41Å; A618-F621 CarbonylContact O-C 3.49Å; V619-F621 VanDerWaalsContact C-N 3.32Å; V619-F621 PolarHBondContact O-N 3.16Å; F621-V623 VanDerWaalsContact C-N 3.34Å; F621-V623 HydrophobicContact CB-CG2 4.27Å; F621-V623 PolarHBondContact O-N 3.48Å
622A97Very high94.5Very high11 Ų1124.3 Ų24.39%0.09113%0.133CC..THydrogen-bonded Turntrans54.840177.100000114.3A618 V619 C620 P624 K674 I677 A678A618-A622 CarbonylContact O-C 3.53Å; A618-A622 WeakPolarHBondContact O-CA 3.27Å; A618-A622 PolarHBondContact O-N 2.86Å; V619-A622 PolarHBondContact O-N 3.2Å; C620-A622 VanDerWaalsContact C-N 3.26Å; C620-A622 PolarHBondContact O-N 3.09Å; A622-P624 WeakPolarHBondContact O-CD 3.43Å; A622-K674 VanDerWaalsContact O-CD 3.24Å; A622-K674 WeakPolarHBondContact O-CD 3.28Å; A622-K674 VanDerWaalsContact O-CE 3.29Å; A622-K674 WeakPolarHBondContact O-CE 3.43Å; A622-K674 PolarHBondContact O-NZ 2.9Å; A622-I677 VanDerWaalsContact C-CG2 3.47Å; A622-I677 HydrophobicContact CB-CG2 4.15Å; A622-I677 VanDerWaalsContact O-CG2 3.26Å; A622-I677 WeakPolarHBondContact O-CG2 3.44Å; A622-A678 HydrophobicContact CB-CB 4.16Å
623V98.3Very high94.4Very high1 Ų125.8 Ų25.81%0.00614%0.141CC..  trans-96.1113.5178.3-174.40000110.7L598 T603 F606 A618 F621 I677L598-V623 HydrophobicContact CD2-CB 4.34Å; L598-V623 HydrophobicContact CD2-CG1 4.31Å; L598-V623 HydrophobicContact CD2-CG2 4.25Å; L598-V623 WeakPolarHBondContact O-CG2 3.32Å; T603-V623 HydrophobicContact CG2-CG1 3.93Å; T603-V623 HydrophobicContact CG2-CG2 4.21Å; F606-V623 HydrophobicContact CB-CG1 3.78Å; A618-V623 HydrophobicContact CB-CB 4.45Å; A618-V623 PolarHBondContact O-N 3.37Å; F621-V623 VanDerWaalsContact C-N 3.34Å; F621-V623 HydrophobicContact CB-CG2 4.27Å; F621-V623 PolarHBondContact O-N 3.48Å; V623-I677 WeakPolarHBondContact O-CD1 3.49Å
624P98.6Very high94.6Very high3 Ų319.7 Ų19.72%0.01912%0.115CC..  trans-53.9153.6174.2-28.237000112.8F606 A622 V667 K674 I677F606-P624 PolarHBondContact N-O 3.49Å; A622-P624 WeakPolarHBondContact O-CD 3.43Å; P624-V667 HydrophobicContact CB-CG1 3.64Å; P624-K674 HydrophobicContact CG-CB 3.89Å; P624-K674 HydrophobicContact CG-CD 3.99Å; P624-I677 HydrophobicContact CG-CG2 4.17Å
625M98.6Very high94.7Very high0 Ų022.7 Ų22.70%013%0.132CC..EExtended strand (participates in β ladder)trans-125144.9-171.6-79.3177.4-80.200114.5F606 T608 F615 A618 V619 M641 F646 G647 I648 I677F606-M625 HydrophobicContact CB-CG 4.01Å; F606-M625 HydrophobicContact CD1-CG 3.82Å; F606-M625 HydrophobicContact CD1-SD 3.91Å; F606-M625 HydrophobicContact CE1-SD 4.48Å; F606-M625 HydrophobicContact CG-CG 4.32Å; F606-M625 CarbonylContact O-C 3.38Å; F606-M625 WeakPolarHBondContact O-CA 3.36Å; T608-M625 HydrophobicContact CG2-CB 4.47Å; T608-M625 HydrophobicContact CG2-CG 4.15Å; T608-M625 HydrophobicContact CG2-SD 3.84Å; F615-M625 HydrophobicContact CD2-CE 3.57Å; F615-M625 HydrophobicContact CD2-SD 3.59Å; F615-M625 VanDerWaalsContact CD2-SD 3.59Å; F615-M625 HydrophobicContact CE2-CE 3.49Å; F615-M625 VanDerWaalsContact CE2-CE 3.49Å; F615-M625 HydrophobicContact CE2-SD 4Å; F615-M625 HydrophobicContact CG-CE 4.33Å; F615-M625 HydrophobicContact CG-SD 4.44Å; F615-M625 HydrophobicContact CZ-CE 4.22Å; A618-M625 HydrophobicContact CB-CE 3.95Å; A618-M625 HydrophobicContact CB-CG 4.17Å; A618-M625 HydrophobicContact CB-SD 3.75Å; V619-M625 HydrophobicContact CG2-CE 4.02Å; M625-M641 HydrophobicContact CB-SD 3.4Å; M625-M641 WeakPolarHBondContact CB-SD 3.38Å; M625-M641 HydrophobicContact CE-SD 4.47Å; M625-F646 HydrophobicContact CE-CD2 3.89Å; M625-F646 HydrophobicContact CE-CE2 3.45Å; M625-F646 VanDerWaalsContact CE-CE2 3.45Å; M625-F646 PolarHBondContact N-O 3.04Å; M625-G647 CarbonylContact O-C 3.55Å; M625-G647 WeakPolarHBondContact O-CA 3.25Å; M625-I648 PolarHBondContact O-N 3.49Å; M625-I648 VanDerWaalsContact O-N 3.13Å; M625-I677 HydrophobicContact CE-CD1 4.21Å
626L98.5Very high94.5Very high0 Ų027.9 Ų27.90%015%0.152CC..EExtended strand (participates in β ladder)trans-111.6118.9160-17763.8000107.2L605 F606 I607 T608 I648 L650 F660 A663 M664L605-L626 HydrophobicContact CD1-CB 4.32Å; F606-L626 PolarHBondContact O-N 3.1Å; I607-L626 CarbonylContact C-O 3.58Å; I607-L626 VanDerWaalsContact CA-O 3.28Å; I607-L626 WeakPolarHBondContact CA-O 3.37Å; I607-L626 HydrophobicContact CB-CB 4.49Å; I607-L626 HydrophobicContact CD1-CD2 4.3Å; I607-L626 HydrophobicContact CG1-CB 4.17Å; I607-L626 HydrophobicContact CG1-CD2 4.37Å; I607-L626 HydrophobicContact CG2-CB 4.24Å; I607-L626 HydrophobicContact CG2-CD2 4.25Å; I607-L626 HydrophobicContact CG2-CG 4.37Å; T608-L626 PolarHBondContact N-O 3.49Å; L626-I648 HydrophobicContact CD1-CB 3.81Å; L626-I648 HydrophobicContact CD1-CG2 4.04Å; L626-L650 HydrophobicContact CD1-CD1 3.58Å; L626-L650 HydrophobicContact CD1-CG 3.73Å; L626-L650 HydrophobicContact CD2-CD1 3.7Å; L626-L650 HydrophobicContact CG-CD1 3.74Å; L626-L650 HydrophobicContact CG-CG 4.32Å; L626-F660 HydrophobicContact CD2-CD2 3.88Å; L626-F660 HydrophobicContact CD2-CE2 3.59Å; L626-F660 HydrophobicContact CD2-CZ 4.47Å; L626-A663 HydrophobicContact CD1-CB 3.7Å; L626-A663 HydrophobicContact CD2-CB 4.34Å; L626-M664 HydrophobicContact CD2-CG 3.66Å
627S98.1Very high94.6Very high0 Ų027.7 Ų27.70%015%0.151CC..EExtended strand (participates in β ladder)trans-111.4131.2-174.5-178.60000113.2T608 S610 T638 I648 R649 L650T608-S627 CarbonylContact O-C 2.98Å; T608-S627 WeakPolarHBondContact O-CA 3.4Å; S610-S627 WeakPolarHBondContact CB-OG 3.26Å; S610-S627 VanDerWaalsContact OG-CB 3.24Å; S610-S627 WeakPolarHBondContact OG-CB 3.01Å; S610-S627 PolarHBondContact OG-OG 3.21Å; S627-T638 PolarHBondContact OG-OG1 2.96Å; S627-I648 PolarHBondContact N-O 2.96Å; S627-R649 CarbonylContact O-C 3.49Å; S627-R649 WeakPolarHBondContact O-CA 3.4Å; S627-L650 PolarHBondContact O-N 2.94Å
628I97.6Very high94.7Very high4 Ų427.1 Ų27.12%0.02115%0.149CC..  trans-119.383.5172-57.3161000107.2F540 I607 T608 H609 L630 L650 K652 L655 F660F540-I628 HydrophobicContact CE1-CB 4.45Å; F540-I628 HydrophobicContact CZ-CB 3.75Å; F540-I628 HydrophobicContact CZ-CD1 3.85Å; F540-I628 HydrophobicContact CZ-CG1 4.32Å; F540-I628 HydrophobicContact CZ-CG2 4.28Å; I607-I628 HydrophobicContact CG2-CD1 4.44Å; T608-I628 PolarHBondContact O-N 2.69Å; H609-I628 WeakPolarHBondContact CA-O 3.32Å; I628-L630 PolarHBondContact O-N 3Å; I628-L650 HydrophobicContact CD1-CD1 4.46Å; I628-L650 HydrophobicContact CG1-CB 3.8Å; I628-L650 HydrophobicContact CG1-CD1 4.22Å; I628-K652 HydrophobicContact CG2-CB 3.73Å; I628-L655 HydrophobicContact CD1-CD1 4.41Å; I628-L655 HydrophobicContact CD1-CD2 4.15Å; I628-F660 HydrophobicContact CD1-CD2 4.33Å; I628-F660 HydrophobicContact CD1-CE2 3.85Å
629P96.1Very high94.6Very high12 Ų1229.6 Ų29.68%0.07817%0.169CC..  trans-65.8133.6-177.626.7-34000110.9Q634 V635 T638 R649P629-Q634 HydrophobicContact CB-CB 3.9Å; P629-V635 HydrophobicContact CB-CG2 4.07Å; P629-V635 HydrophobicContact CG-CG2 4.45Å; P629-T638 HydrophobicContact CG-CG2 4.34Å; P629-R649 HydrophobicContact CG-CG 4.32Å
630L94.1Very high94.4Very high42 Ų4229.9 Ų29.922%0.2217%0.17CC..  trans-93-46.2-178.5-59.1-179.3000112.2F540 A544 H609 I628 K652F540-L630 HydrophobicContact CD1-CD1 4.01Å; F540-L630 HydrophobicContact CD1-CD2 4.4Å; F540-L630 HydrophobicContact CD1-CG 4.45Å; F540-L630 HydrophobicContact CE1-CD2 4.16Å; A544-L630 HydrophobicContact CB-CD1 3.72Å; H609-L630 HydrophobicContact CB-CD1 4.37Å; H609-L630 HydrophobicContact CB-CG 4.17Å; I628-L630 PolarHBondContact O-N 3Å; L630-K652 HydrophobicContact CD2-CD 4.08Å; L630-K652 PolarHBondContact O-NZ 3.13Å
631F91.4Very high94.5Very high113 Ų11329.3 Ų29.350%0.49617%0.167SC..SBendtrans-166.3171.3-178.861.5-90000112.9L543 Q634L543-F631 HydrophobicContact CD1-CZ 4.35Å; F631-Q634 VanDerWaalsContact N-OE1 3.16Å; F631-Q634 VanDerWaalsContact O-CB 3.25Å; F631-Q634 WeakPolarHBondContact O-CB 3.43Å; F631-Q634 VanDerWaalsContact O-CG 3.31Å; F631-Q634 WeakPolarHBondContact O-CG 3.48Å; F631-Q634 PolarHBondContact O-NE2 3.11Å; F631-Q634 PolarHBondContact O-OE1 3.18Å
632G89.4Confident94.5Very high57 Ų5730.8 Ų30.859%0.58818%0.179SC*.THydrogen-bonded Turntrans67.1-140167.300000115.1Q634G632-Q634 PolarHBondContact O-N 2.73Å
633D88.2Confident94.2Very high81 Ų8135.4 Ų35.443%0.43320%0.2SC..THydrogen-bonded Turntrans-65.5-22.1-179.164.4-34.7000113.5V635 R636 I637D633-V635 PolarHBondContact O-N 3.34Å; D633-R636 WeakPolarHBondContact O-CB 3.38Å; D633-R636 PolarHBondContact O-N 2.83Å; D633-I637 HydrophobicContact CB-CD1 4.41Å; D633-I637 WeakPolarHBondContact O-CG1 3.49Å; D633-I637 PolarHBondContact O-N 3.31Å; D633-I637 WeakPolarHBondContact OD2-CD1 3.22Å
634Q93Very high93.8Very high9 Ų935.6 Ų35.64%0.04220%0.201CC..Hα-helixtrans-52.6-38.7177.9-63162.225.800112.7H609 P629 F631 G632 R636 I637 T638H609-Q634 PolarHBondContact CD2-NE2 3.28Å; H609-Q634 VanDerWaalsContact O-CB 3.25Å; H609-Q634 WeakPolarHBondContact O-CB 3.48Å; H609-Q634 WeakPolarHBondContact O-CG 3.34Å; P629-Q634 HydrophobicContact CB-CB 3.9Å; F631-Q634 VanDerWaalsContact N-OE1 3.16Å; F631-Q634 VanDerWaalsContact O-CB 3.25Å; F631-Q634 WeakPolarHBondContact O-CB 3.43Å; F631-Q634 VanDerWaalsContact O-CG 3.31Å; F631-Q634 WeakPolarHBondContact O-CG 3.48Å; F631-Q634 PolarHBondContact O-NE2 3.11Å; F631-Q634 PolarHBondContact O-OE1 3.18Å; G632-Q634 PolarHBondContact O-N 2.73Å; Q634-R636 VanDerWaalsContact C-N 3.34Å; Q634-R636 PolarHBondContact O-N 3.47Å; Q634-I637 PolarHBondContact O-N 2.03Å; Q634-T638 VanDerWaalsContact O-CB 3.24Å; Q634-T638 WeakPolarHBondContact O-CB 3.46Å; Q634-T638 PolarHBondContact O-N 2.82Å; Q634-T638 PolarHBondContact O-OG1 2.92Å
635V93.3Very high93.6Very high75 Ų7536.3 Ų36.346%0.45521%0.208SC..Hα-helixtrans-62.6-43.2178.6179.10000110.7P629 D633 A639P629-V635 HydrophobicContact CB-CG2 4.07Å; P629-V635 HydrophobicContact CG-CG2 4.45Å; D633-V635 PolarHBondContact O-N 3.34Å; V635-A639 PolarHBondContact O-N 3.37Å
636R90.4Very high93.5Very high109 Ų10936.3 Ų36.341%0.41121%0.208SC..Hα-helixtrans-68.2-46.7177.8179.8-171.7178.7-87.24.3111.3D497 D633 Q634 T638 A639 L640D497-R636 IonicContact OD1-CZ 3.3Å; D497-R636 IonicContact OD1-NH1 2.63Å; D497-R636 IonicContact OD1-NH2 2.83Å; D497-R636 PolarHBondContact OD1-NH2 3.21Å; D497-R636 IonicContact OD2-CZ 3.61Å; D497-R636 IonicContact OD2-NH1 3.38Å; D497-R636 PolarHBondContact OD2-NH1 3.42Å; D497-R636 VanDerWaalsContact OD2-NH1 3.1Å; D497-R636 IonicContact OD2-NH2 3.96Å; D497-R636 PolarHBondContact OD2-NH2 3.45Å; D633-R636 WeakPolarHBondContact O-CB 3.38Å; D633-R636 PolarHBondContact O-N 2.83Å; Q634-R636 VanDerWaalsContact C-N 3.34Å; Q634-R636 PolarHBondContact O-N 3.47Å; R636-T638 VanDerWaalsContact C-N 3.25Å; R636-T638 PolarHBondContact O-N 3.2Å; R636-A639 WeakPolarHBondContact O-CB 3.47Å; R636-A639 PolarHBondContact O-N 3.14Å; R636-A639 VanDerWaalsContact O-N 3.08Å; R636-L640 PolarHBondContact O-N 3.01Å
637I92Very high93.5Very high3 Ų336.5 Ų36.52%0.01521%0.21CC..Hα-helixtrans-59.1-42.4178.5-64.5168000110.3M492 S610 I612 F615 D633 Q634 A639 L640 M641M492-I637 HydrophobicContact CE-CD1 3.85Å; M492-I637 HydrophobicContact CE-CG1 3.86Å; M492-I637 HydrophobicContact CE-CG2 4Å; M492-I637 HydrophobicContact CG-CG1 4.44Å; M492-I637 HydrophobicContact SD-CG1 4.14Å; M492-I637 HydrophobicContact SD-CG2 4.15Å; S610-I637 WeakPolarHBondContact O-CD1 3.37Å; I612-I637 HydrophobicContact CB-CD1 3.95Å; I612-I637 HydrophobicContact CD1-CD1 4.14Å; I612-I637 HydrophobicContact CG1-CD1 4.43Å; F615-I637 HydrophobicContact CB-CG2 4.14Å; F615-I637 HydrophobicContact CD1-CG2 3.65Å; F615-I637 HydrophobicContact CD2-CG2 3.47Å; F615-I637 VanDerWaalsContact CD2-CG2 3.47Å; F615-I637 HydrophobicContact CE1-CG2 3.77Å; F615-I637 HydrophobicContact CE2-CG2 3.61Å; F615-I637 HydrophobicContact CG-CG2 3.46Å; F615-I637 VanDerWaalsContact CG-CG2 3.46Å; F615-I637 HydrophobicContact CZ-CG2 3.74Å; D633-I637 HydrophobicContact CB-CD1 4.41Å; D633-I637 WeakPolarHBondContact O-CG1 3.49Å; D633-I637 PolarHBondContact O-N 3.31Å; D633-I637 WeakPolarHBondContact OD2-CD1 3.22Å; Q634-I637 PolarHBondContact O-N 2.03Å; I637-A639 VanDerWaalsContact C-N 3.34Å; I637-A639 PolarHBondContact O-N 2.83Å; I637-L640 WeakPolarHBondContact O-CB 3.25Å; I637-L640 PolarHBondContact O-N 3.23Å; I637-M641 PolarHBondContact O-N 3.1Å
638T95.2Very high93.5Very high0 Ų037.8 Ų37.80%022%0.217CC..Hα-helixtrans-62.9-40.2175.6-580000112.2S610 S627 P629 Q634 R636 L640 M641 V642 R649S610-T638 WeakPolarHBondContact CB-OG1 3.47Å; S610-T638 PolarHBondContact OG-OG1 3.27Å; S627-T638 PolarHBondContact OG-OG1 2.96Å; P629-T638 HydrophobicContact CG-CG2 4.34Å; Q634-T638 VanDerWaalsContact O-CB 3.24Å; Q634-T638 WeakPolarHBondContact O-CB 3.46Å; Q634-T638 PolarHBondContact O-N 2.82Å; Q634-T638 PolarHBondContact O-OG1 2.92Å; R636-T638 VanDerWaalsContact C-N 3.25Å; R636-T638 PolarHBondContact O-N 3.2Å; T638-L640 VanDerWaalsContact C-N 3.33Å; T638-L640 PolarHBondContact O-N 3.5Å; T638-M641 HydrophobicContact CG2-CE 3.94Å; T638-M641 WeakPolarHBondContact O-CB 3.4Å; T638-M641 PolarHBondContact O-N 2.98Å; T638-V642 WeakPolarHBondContact O-CG2 3.37Å; T638-V642 PolarHBondContact O-N 2.79Å; T638-V642 VanDerWaalsContact O-N 3.09Å; T638-R649 HydrophobicContact CG2-CB 3.53Å; T638-R649 HydrophobicContact CG2-CG 3.46Å; T638-R649 VanDerWaalsContact CG2-CG 3.46Å
639A93.4Very high93.5Very high52 Ų5243.9 Ų43.943%0.4324%0.239SC..Hα-helixtrans-63.3-38.7175.400000112V635 R636 I637 V642 M643V635-A639 PolarHBondContact O-N 3.37Å; R636-A639 WeakPolarHBondContact O-CB 3.47Å; R636-A639 PolarHBondContact O-N 3.14Å; R636-A639 VanDerWaalsContact O-N 3.08Å; I637-A639 VanDerWaalsContact C-N 3.34Å; I637-A639 PolarHBondContact O-N 2.83Å; A639-V642 PolarHBondContact O-N 3.47Å; A639-M643 WeakPolarHBondContact O-CB 3.24Å; A639-M643 PolarHBondContact O-N 3.49Å
640L90.9Very high93.6Very high5 Ų544.3 Ų44.33%0.02624%0.241CC..Hα-helixtrans-63.4-42.7174.5-67.3172000111.8M492 I498 R636 I637 T638 V642 M643 H644M492-L640 HydrophobicContact CG-CD1 4.15Å; M492-L640 HydrophobicContact SD-CD1 4.44Å; I498-L640 HydrophobicContact CG1-CD2 4.11Å; R636-L640 PolarHBondContact O-N 3.01Å; I637-L640 WeakPolarHBondContact O-CB 3.25Å; I637-L640 PolarHBondContact O-N 3.23Å; T638-L640 VanDerWaalsContact C-N 3.33Å; T638-L640 PolarHBondContact O-N 3.5Å; L640-V642 PolarHBondContact O-N 3.19Å; L640-M643 HydrophobicContact CD2-CE 4.1Å; L640-M643 HydrophobicContact CD2-SD 4.42Å; L640-M643 WeakPolarHBondContact O-CB 3.38Å; L640-M643 PolarHBondContact O-N 2.99Å; L640-H644 PolarHBondContact O-N 2.8Å; L640-H644 PolarHBondContact O-ND1 3.31Å
641M94.5Very high93.6Very high0 Ų045 Ų450%025%0.245CC..Hα-helixtrans-58.3-45174.4170.5-169.380.400113.1F615 M625 I637 T638 H644 G645 F646 I648F615-M641 HydrophobicContact CE2-CB 3.75Å; F615-M641 HydrophobicContact CE2-CG 4.31Å; F615-M641 HydrophobicContact CE2-SD 4.4Å; F615-M641 HydrophobicContact CZ-CB 3.96Å; M625-M641 HydrophobicContact CB-SD 3.4Å; M625-M641 WeakPolarHBondContact CB-SD 3.38Å; M625-M641 HydrophobicContact CE-SD 4.47Å; I637-M641 PolarHBondContact O-N 3.1Å; T638-M641 HydrophobicContact CG2-CE 3.94Å; T638-M641 WeakPolarHBondContact O-CB 3.4Å; T638-M641 PolarHBondContact O-N 2.98Å; M641-H644 PolarHBondContact O-N 3.01Å; M641-G645 PolarHBondContact O-N 3.14Å; M641-F646 HydrophobicContact CB-CD2 4.26Å; M641-F646 HydrophobicContact CB-CE2 3.68Å; M641-F646 HydrophobicContact CB-CZ 3.98Å; M641-F646 HydrophobicContact CG-CD2 3.55Å; M641-F646 HydrophobicContact CG-CE2 3.44Å; M641-F646 VanDerWaalsContact CG-CE2 3.44Å; M641-F646 HydrophobicContact CG-CG 4.34Å; M641-F646 HydrophobicContact CG-CZ 4.18Å; M641-F646 PolarHBondContact O-N 3.45Å; M641-I648 WeakPolarHBondContact CE-O 3.39Å
642V95.6Very high93.7Very high70 Ų7044.3 Ų44.342%0.42424%0.242SC..Hα-helixtrans-66.8-42.8177.9173.70000110.5T638 A639 L640 H644 G645 R649T638-V642 WeakPolarHBondContact O-CG2 3.37Å; T638-V642 PolarHBondContact O-N 2.79Å; T638-V642 VanDerWaalsContact O-N 3.09Å; A639-V642 PolarHBondContact O-N 3.47Å; L640-V642 PolarHBondContact O-N 3.19Å; V642-H644 VanDerWaalsContact C-N 3.32Å; V642-H644 PolarHBondContact O-N 3.02Å; V642-G645 WeakPolarHBondContact O-CA 3.26Å; V642-G645 PolarHBondContact O-N 3.29Å; V642-R649 HydrophobicContact CG2-CB 3.98Å
643M90.7Very high93.8Very high107 Ų10746.7 Ų46.753%0.52725%0.245SC..Hα-helixtrans-56.6-44.4175.9179.5-163.1-63.700111.9I498 A639 L640 G645I498-M643 HydrophobicContact CD1-CE 4.01Å; I498-M643 HydrophobicContact CG1-CE 3.88Å; I498-M643 HydrophobicContact CG1-SD 4.45Å; A639-M643 WeakPolarHBondContact O-CB 3.24Å; A639-M643 PolarHBondContact O-N 3.49Å; L640-M643 HydrophobicContact CD2-CE 4.1Å; L640-M643 HydrophobicContact CD2-SD 4.42Å; L640-M643 WeakPolarHBondContact O-CB 3.38Å; L640-M643 PolarHBondContact O-N 2.99Å; M643-G645 PolarHBondContact O-N 3.4Å
644H91Very high94Very high6 Ų650.1 Ų50.13%0.02826%0.256CS..THydrogen-bonded Turntrans-78.5-6.9177.1-70.189.7000113.3M495 L496 L640 M641 V642 F646 R676 L680M495-H644 PolarHBondContact O-NE2 2.72Å; L496-H644 PolarHBondContact O-CE1 2.95Å; L640-H644 PolarHBondContact O-N 2.8Å; L640-H644 PolarHBondContact O-ND1 3.31Å; M641-H644 PolarHBondContact O-N 3.01Å; V642-H644 VanDerWaalsContact C-N 3.32Å; V642-H644 PolarHBondContact O-N 3.02Å; H644-F646 HydrophobicContact CB-CD1 3.41Å; H644-F646 VanDerWaalsContact CB-CD1 3.41Å; H644-F646 HydrophobicContact CB-CE1 3.29Å; H644-F646 HydrophobicContact CB-CZ 4.46Å; H644-F646 AromaticContact CG-CE1 3.94Å; H644-F646 PolarHBondContact O-N 3.37Å; H644-R676 WeakPolarHBondContact O-CD 3.35Å; H644-L680 HydrophobicContact CB-CD1 3.97Å
645G94.3Very high94.1Very high17 Ų1750.4 Ų50.418%0.17526%0.258CS..THydrogen-bonded Turntrans72.323.9172.900000114.9M641 V642 M643 Y673 R676M641-G645 PolarHBondContact O-N 3.14Å; V642-G645 WeakPolarHBondContact O-CA 3.26Å; V642-G645 PolarHBondContact O-N 3.29Å; M643-G645 PolarHBondContact O-N 3.4Å; G645-Y673 WeakPolarHBondContact O-CD1 3.25Å; G645-R676 WeakPolarHBondContact O-CD 3.41Å
646F96.3Very high94.3Very high0 Ų049.7 Ų49.70%025%0.253CS..SBendtrans-105.810.8177.260.6-100.1000114.9L496 F615 V619 M625 M641 H644 R676 I677 L680L496-F646 HydrophobicContact CD2-CE1 4.08Å; L496-F646 HydrophobicContact CD2-CZ 4.25Å; F615-F646 HydrophobicContact CE1-CZ 4.4Å; F615-F646 AromaticContact CE2-CE2 3.98Å; F615-F646 HydrophobicContact CE2-CE2 3.98Å; F615-F646 HydrophobicContact CE2-CZ 4.33Å; F615-F646 AromaticContact CZ-CE2 3.77Å; F615-F646 HydrophobicContact CZ-CE2 3.77Å; F615-F646 AromaticContact CZ-CZ 3.66Å; F615-F646 HydrophobicContact CZ-CZ 3.66Å; V619-F646 HydrophobicContact CG2-CE2 3.97Å; V619-F646 HydrophobicContact CG2-CZ 4Å; M625-F646 HydrophobicContact CE-CD2 3.89Å; M625-F646 HydrophobicContact CE-CE2 3.45Å; M625-F646 VanDerWaalsContact CE-CE2 3.45Å; M625-F646 PolarHBondContact N-O 3.04Å; M641-F646 HydrophobicContact CB-CD2 4.26Å; M641-F646 HydrophobicContact CB-CE2 3.68Å; M641-F646 HydrophobicContact CB-CZ 3.98Å; M641-F646 HydrophobicContact CG-CD2 3.55Å; M641-F646 HydrophobicContact CG-CE2 3.44Å; M641-F646 VanDerWaalsContact CG-CE2 3.44Å; M641-F646 HydrophobicContact CG-CG 4.34Å; M641-F646 HydrophobicContact CG-CZ 4.18Å; M641-F646 PolarHBondContact O-N 3.45Å; H644-F646 HydrophobicContact CB-CD1 3.41Å; H644-F646 VanDerWaalsContact CB-CD1 3.41Å; H644-F646 HydrophobicContact CB-CE1 3.29Å; H644-F646 HydrophobicContact CB-CZ 4.46Å; H644-F646 AromaticContact CG-CE1 3.94Å; H644-F646 PolarHBondContact O-N 3.37Å; F646-R676 HydrophobicContact CB-CB 4.38Å; F646-I677 HydrophobicContact CB-CB 3.67Å; F646-I677 HydrophobicContact CB-CD1 4.45Å; F646-I677 HydrophobicContact CB-CG1 4.23Å; F646-I677 HydrophobicContact CD2-CB 4.44Å; F646-I677 HydrophobicContact CD2-CD1 3.75Å; F646-I677 HydrophobicContact CD2-CG1 4.06Å; F646-I677 HydrophobicContact CE2-CD1 4.27Å; F646-I677 HydrophobicContact CG-CB 4.05Å; F646-I677 HydrophobicContact CG-CD1 4.23Å; F646-I677 HydrophobicContact CG-CG1 4.07Å; F646-L680 HydrophobicContact CD1-CD1 3.5Å; F646-L680 HydrophobicContact CE1-CD1 3.41Å; F646-L680 VanDerWaalsContact CE1-CD1 3.41Å
647G97.9Very high94.6Very high4 Ų449 Ų494%0.04125%0.251CS..EExtended strand (participates in β ladder)trans-167.4179.2170.600000114.4M625M625-G647 CarbonylContact O-C 3.55Å; M625-G647 WeakPolarHBondContact O-CA 3.25Å
648I98.4Very high94.8Very high27 Ų2754.3 Ų54.314%0.13828%0.276CS..EExtended strand (participates in β ladder)trans-119138.5179.8-62.3179.2000109.5M625 L626 S627 M641 A663 K666 V667 Y673M625-I648 PolarHBondContact O-N 3.49Å; M625-I648 VanDerWaalsContact O-N 3.13Å; L626-I648 HydrophobicContact CD1-CB 3.81Å; L626-I648 HydrophobicContact CD1-CG2 4.04Å; S627-I648 PolarHBondContact N-O 2.96Å; M641-I648 WeakPolarHBondContact CE-O 3.39Å; I648-A663 HydrophobicContact CG2-CB 4.38Å; I648-K666 HydrophobicContact CD1-CB 4.13Å; I648-K666 HydrophobicContact CD1-CD 3.71Å; I648-K666 HydrophobicContact CD1-CG 3.99Å; I648-V667 HydrophobicContact CB-CG2 4.46Å; I648-V667 HydrophobicContact CD1-CG2 3.62Å; I648-V667 HydrophobicContact CG1-CG2 3.84Å; I648-Y673 HydrophobicContact CG1-CE1 4.11Å
649R97.9Very high94.9Very high132 Ų13257.1 Ų57.150%0.49829%0.293SS..EExtended strand (participates in β ladder)trans-90132.9168.8-175.9171.278.789.90.4110.3S627 P629 T638 V642S627-R649 CarbonylContact O-C 3.49Å; S627-R649 WeakPolarHBondContact O-CA 3.4Å; P629-R649 HydrophobicContact CG-CG 4.32Å; T638-R649 HydrophobicContact CG2-CB 3.53Å; T638-R649 HydrophobicContact CG2-CG 3.46Å; T638-R649 VanDerWaalsContact CG2-CG 3.46Å; V642-R649 HydrophobicContact CG2-CB 3.98Å
650L97.8Very high95.2Very high21 Ų2154.7 Ų54.711%0.1127%0.273CS..  trans-111.6147.3168.2-71177.6000110.7L626 S627 I628 L655 F660 A663L626-L650 HydrophobicContact CD1-CD1 3.58Å; L626-L650 HydrophobicContact CD1-CG 3.73Å; L626-L650 HydrophobicContact CD2-CD1 3.7Å; L626-L650 HydrophobicContact CG-CD1 3.74Å; L626-L650 HydrophobicContact CG-CG 4.32Å; S627-L650 PolarHBondContact O-N 2.94Å; I628-L650 HydrophobicContact CD1-CD1 4.46Å; I628-L650 HydrophobicContact CG1-CB 3.8Å; I628-L650 HydrophobicContact CG1-CD1 4.22Å; L650-L655 HydrophobicContact CB-CD1 4.18Å; L650-L655 HydrophobicContact CD1-CD1 3.72Å; L650-L655 HydrophobicContact CG-CD1 4.42Å; L650-F660 HydrophobicContact CD1-CD2 3.6Å; L650-F660 HydrophobicContact CD1-CE2 4.22Å; L650-A663 HydrophobicContact CD1-CB 4.1Å; L650-A663 HydrophobicContact CD2-CB 3.87Å; L650-A663 HydrophobicContact CG-CB 4.28Å
651D94.7Very high95.5Very high58 Ų5857.1 Ų57.131%0.3128%0.282SS..  trans-93.3117.7175.2-173-24.1000109.1T653 K654 L655D651-T653 VanDerWaalsContact CG-OG1 3.29Å; D651-T653 PolarHBondContact O-N 3.13Å; D651-T653 VanDerWaalsContact O-N 3.13Å; D651-T653 WeakPolarHBondContact OD1-CB 3.37Å; D651-T653 PolarHBondContact OD1-N 2.97Å; D651-T653 PolarHBondContact OD1-OG1 3.04Å; D651-T653 PolarHBondContact OD2-OG1 3.41Å; D651-K654 HydrophobicContact CB-CB 4.35Å; D651-K654 PolarHBondContact O-N 2.87Å; D651-K654 VanDerWaalsContact O-N 3.09Å; D651-L655 PolarHBondContact O-N 2.69Å
652K92Very high95.7Very high98 Ų9860.6 Ų60.643%0.42631%0.306SS..G310 helixtrans-58.5-25.6-179.271.7-177.6-173.7-179.40113.3I628 L630I628-K652 HydrophobicContact CG2-CB 3.73Å; L630-K652 HydrophobicContact CD2-CD 4.08Å; L630-K652 PolarHBondContact O-NZ 3.13Å
653T91.6Very high95.8Very high106 Ų10657.7 Ų57.765%0.6529%0.289SS*.G310 helixtrans-82.8-15.5-178.765.70000113.6D651D651-T653 VanDerWaalsContact CG-OG1 3.29Å; D651-T653 PolarHBondContact O-N 3.13Å; D651-T653 VanDerWaalsContact O-N 3.13Å; D651-T653 WeakPolarHBondContact OD1-CB 3.37Å; D651-T653 PolarHBondContact OD1-N 2.97Å; D651-T653 PolarHBondContact OD1-OG1 3.04Å; D651-T653 PolarHBondContact OD2-OG1 3.41Å
654K92.7Very high96.1Very high154 Ų15452.6 Ų52.667%0.6726%0.264SS*.G310 helixtrans-118.915-178-58.2-179.6-177.31790111.9D651 T656D651-K654 HydrophobicContact CB-CB 4.35Å; D651-K654 PolarHBondContact O-N 2.87Å; D651-K654 VanDerWaalsContact O-N 3.09Å; K654-T656 PolarHBondContact O-N 3Å
655L95.6Very high96.5Very high14 Ų1456.7 Ų56.77%0.07328%0.28CS..  trans-74.9122-176.2-163.176000109.5I553 I557 I628 L650 D651 F660I553-L655 HydrophobicContact CD1-CB 3.83Å; I553-L655 HydrophobicContact CG2-CD2 4.02Å; I557-L655 HydrophobicContact CD1-CD2 4.02Å; I557-L655 HydrophobicContact CG1-CD2 3.86Å; I628-L655 HydrophobicContact CD1-CD1 4.41Å; I628-L655 HydrophobicContact CD1-CD2 4.15Å; L650-L655 HydrophobicContact CB-CD1 4.18Å; L650-L655 HydrophobicContact CD1-CD1 3.72Å; L650-L655 HydrophobicContact CG-CD1 4.42Å; D651-L655 PolarHBondContact O-N 2.69Å; L655-F660 HydrophobicContact CD1-CB 4.02Å; L655-F660 HydrophobicContact CD1-CD2 3.93Å; L655-F660 HydrophobicContact CD1-CG 4.32Å; L655-F660 HydrophobicContact CG-CB 4.38Å
656T96.8Very high96.7Very high60 Ų6061.3 Ų61.337%0.36830%0.295SS..  trans-128.1166.1176.359.50000108.8K654 E658 T659 F660K654-T656 PolarHBondContact O-N 3Å; T656-E658 PolarHBondContact O-N 3.11Å; T656-T659 PolarHBondContact N-OG1 2.81Å; T656-T659 PolarHBondContact O-N 2.99Å; T656-T659 PolarHBondContact O-OG1 3.46Å; T656-T659 VanDerWaalsContact O-OG1 3.11Å; T656-T659 WeakPolarHBondContact OG1-CB 3.43Å; T656-T659 VanDerWaalsContact OG1-CG2 3.29Å; T656-T659 WeakPolarHBondContact OG1-CG2 3.41Å; T656-T659 PolarHBondContact OG1-N 3.16Å; T656-T659 PolarHBondContact OG1-OG1 3.17Å; T656-F660 VanDerWaalsContact O-CB 3.31Å; T656-F660 WeakPolarHBondContact O-CB 3.43Å; T656-F660 PolarHBondContact O-N 2.92Å
657R97Very high96.8Very high96 Ų9661.8 Ų61.836%0.36230%0.297SS..Hα-helixtrans-54.7-44.7176.1175.6-173.4179.3-138.33.1110.8A559 A560 Y661A559-R657 HydrophobicContact CB-CG 4.03Å; A559-R657 PolarHBondContact O-NE 3.25Å; A559-R657 VanDerWaalsContact O-NE 3.13Å; A560-R657 HydrophobicContact CB-CG 4.3Å; R657-Y661 VanDerWaalsContact O-CB 3.23Å; R657-Y661 WeakPolarHBondContact O-CB 3.22Å; R657-Y661 PolarHBondContact O-N 2.84Å
658E97.5Very high96.7Very high113 Ų11363 Ų6353%0.52830%0.303SS..Hα-helixtrans-70.5-44.7-175.5-63.465.9-14000111.3T656 S662T656-E658 PolarHBondContact O-N 3.11Å; E658-S662 WeakPolarHBondContact O-CB 3.43Å; E658-S662 PolarHBondContact O-N 3.31Å
659T97.2Very high96.7Very high60 Ų6066.6 Ų66.637%0.36832%0.319SS..Hα-helixtrans-67.7-39.6179.553.50000111.6T656 A663T656-T659 PolarHBondContact N-OG1 2.81Å; T656-T659 PolarHBondContact O-N 2.99Å; T656-T659 PolarHBondContact O-OG1 3.46Å; T656-T659 VanDerWaalsContact O-OG1 3.11Å; T656-T659 WeakPolarHBondContact OG1-CB 3.43Å; T656-T659 VanDerWaalsContact OG1-CG2 3.29Å; T656-T659 WeakPolarHBondContact OG1-CG2 3.41Å; T656-T659 PolarHBondContact OG1-N 3.16Å; T656-T659 PolarHBondContact OG1-OG1 3.17Å; T659-A663 WeakPolarHBondContact O-CB 3.47Å; T659-A663 PolarHBondContact O-N 3.5Å; T659-A663 VanDerWaalsContact O-N 3.09Å
660F98Very high96.7Very high0 Ų063.2 Ų63.20%031%0.311CS..Hα-helixtrans-68.6-47.5177.7-169.5-122.6000111.7F538 I557 A560 F561 I607 L626 I628 L650 L655 T656 A663 M664F538-F660 HydrophobicContact CZ-CZ 4.36Å; I557-F660 HydrophobicContact CB-CD1 4.28Å; I557-F660 HydrophobicContact CB-CE1 4.02Å; I557-F660 HydrophobicContact CG1-CD1 4.1Å; I557-F660 HydrophobicContact CG1-CE1 3.98Å; I557-F660 HydrophobicContact CG1-CZ 4.31Å; I557-F660 HydrophobicContact CG2-CD1 4.23Å; I557-F660 HydrophobicContact CG2-CE1 3.5Å; I557-F660 HydrophobicContact CG2-CZ 4.04Å; A560-F660 HydrophobicContact CB-CB 4.39Å; A560-F660 HydrophobicContact CB-CD1 3.66Å; A560-F660 HydrophobicContact CB-CG 4.5Å; F561-F660 HydrophobicContact CD1-CE1 4.17Å; F561-F660 AromaticContact CE1-CE1 3.6Å; F561-F660 HydrophobicContact CE1-CE1 3.6Å; F561-F660 HydrophobicContact CE1-CZ 4.04Å; F561-F660 AromaticContact CZ-CE1 3.92Å; F561-F660 HydrophobicContact CZ-CE1 3.92Å; F561-F660 HydrophobicContact CZ-CZ 4.15Å; I607-F660 HydrophobicContact CD1-CE1 4.43Å; I607-F660 HydrophobicContact CD1-CE2 4.18Å; I607-F660 HydrophobicContact CD1-CZ 3.61Å; I607-F660 HydrophobicContact CG2-CE2 3.95Å; I607-F660 HydrophobicContact CG2-CZ 4.05Å; L626-F660 HydrophobicContact CD2-CD2 3.88Å; L626-F660 HydrophobicContact CD2-CE2 3.59Å; L626-F660 HydrophobicContact CD2-CZ 4.47Å; I628-F660 HydrophobicContact CD1-CD2 4.33Å; I628-F660 HydrophobicContact CD1-CE2 3.85Å; L650-F660 HydrophobicContact CD1-CD2 3.6Å; L650-F660 HydrophobicContact CD1-CE2 4.22Å; L655-F660 HydrophobicContact CD1-CB 4.02Å; L655-F660 HydrophobicContact CD1-CD2 3.93Å; L655-F660 HydrophobicContact CD1-CG 4.32Å; L655-F660 HydrophobicContact CG-CB 4.38Å; T656-F660 VanDerWaalsContact O-CB 3.31Å; T656-F660 WeakPolarHBondContact O-CB 3.43Å; T656-F660 PolarHBondContact O-N 2.92Å; F660-A663 PolarHBondContact O-N 3.08Å; F660-M664 HydrophobicContact CD1-CE 3.62Å; F660-M664 HydrophobicContact CD1-SD 4.29Å; F660-M664 HydrophobicContact CE1-CE 3.71Å; F660-M664 HydrophobicContact CE1-SD 3.85Å; F660-M664 HydrophobicContact CG-CE 4.29Å; F660-M664 HydrophobicContact CZ-CE 4.48Å; F660-M664 HydrophobicContact CZ-SD 4.1Å; F660-M664 WeakPolarHBondContact O-CG 3.41Å; F660-M664 PolarHBondContact O-N 3.15Å
661Y98.1Very high96.6Very high57 Ų5771.9 Ų71.922%0.22434%0.342CS..Hα-helixtrans-58.5-49.1174.7173.5-100000112.1Q563 L564 R657 A663 M664 W665Q563-Y661 HydrophobicContact CB-CD2 3.52Å; Q563-Y661 HydrophobicContact CB-CE2 3.37Å; Q563-Y661 HydrophobicContact CB-CG 4.41Å; Q563-Y661 HydrophobicContact CG-CD2 4.36Å; Q563-Y661 HydrophobicContact CG-CE2 4.45Å; L564-Y661 HydrophobicContact CD2-CD2 4.42Å; L564-Y661 HydrophobicContact CD2-CE2 3.78Å; L564-Y661 HydrophobicContact CG-CD2 4.25Å; L564-Y661 HydrophobicContact CG-CE2 4.01Å; R657-Y661 VanDerWaalsContact O-CB 3.23Å; R657-Y661 WeakPolarHBondContact O-CB 3.22Å; R657-Y661 PolarHBondContact O-N 2.84Å; Y661-A663 VanDerWaalsContact C-N 3.31Å; Y661-A663 PolarHBondContact O-N 2.83Å; Y661-M664 PolarHBondContact O-N 3.37Å; Y661-W665 WeakPolarHBondContact O-CB 3.43Å; Y661-W665 PolarHBondContact O-N 3.32Å
662S98Very high96.8Very high73 Ų7370.7 Ų70.751%0.5134%0.338SS..Hα-helixtrans-58.7-42.8-179.6-178.20000111.9E658 W665 K666E658-S662 WeakPolarHBondContact O-CB 3.43Å; E658-S662 PolarHBondContact O-N 3.31Å; S662-W665 PolarHBondContact O-N 3.02Å; S662-K666 WeakPolarHBondContact O-CB 3.44Å; S662-K666 PolarHBondContact O-N 3.43Å
663A98.1Very high97.1Very high8 Ų867.1 Ų67.17%0.06632%0.323CS..Hα-helixtrans-68.2-42.4178.500000112.7L626 I648 L650 T659 F660 Y661 K666 V667L626-A663 HydrophobicContact CD1-CB 3.7Å; L626-A663 HydrophobicContact CD2-CB 4.34Å; I648-A663 HydrophobicContact CG2-CB 4.38Å; L650-A663 HydrophobicContact CD1-CB 4.1Å; L650-A663 HydrophobicContact CD2-CB 3.87Å; L650-A663 HydrophobicContact CG-CB 4.28Å; T659-A663 WeakPolarHBondContact O-CB 3.47Å; T659-A663 PolarHBondContact O-N 3.5Å; T659-A663 VanDerWaalsContact O-N 3.09Å; F660-A663 PolarHBondContact O-N 3.08Å; Y661-A663 VanDerWaalsContact C-N 3.31Å; Y661-A663 PolarHBondContact O-N 2.83Å; A663-K666 PolarHBondContact O-N 3.06Å; A663-V667 PolarHBondContact O-N 3Å
664M98.3Very high97.4Very high0 Ų066.2 Ų66.20%031%0.31CS..Hα-helixtrans-59.4-50.6172.6-71.8-172-69.200110.9A560 F561 L564 L605 I607 L626 F660 Y661 K666 V667 L668A560-M664 HydrophobicContact CB-CE 3.89Å; F561-M664 HydrophobicContact CD1-CE 3.92Å; F561-M664 HydrophobicContact CD1-SD 3.87Å; F561-M664 HydrophobicContact CE1-CE 4.13Å; F561-M664 HydrophobicContact CE1-SD 3.57Å; F561-M664 VanDerWaalsContact CE1-SD 3.57Å; L564-M664 HydrophobicContact CD1-CB 4.31Å; L564-M664 HydrophobicContact CD1-CE 3.85Å; L564-M664 HydrophobicContact CD1-SD 4.02Å; L605-M664 HydrophobicContact CD2-CB 4.23Å; L605-M664 HydrophobicContact CD2-CG 4.11Å; I607-M664 HydrophobicContact CD1-CG 3.99Å; I607-M664 HydrophobicContact CD1-SD 3.6Å; I607-M664 VanDerWaalsContact CD1-SD 3.6Å; L626-M664 HydrophobicContact CD2-CG 3.66Å; F660-M664 HydrophobicContact CD1-CE 3.62Å; F660-M664 HydrophobicContact CD1-SD 4.29Å; F660-M664 HydrophobicContact CE1-CE 3.71Å; F660-M664 HydrophobicContact CE1-SD 3.85Å; F660-M664 HydrophobicContact CG-CE 4.29Å; F660-M664 HydrophobicContact CZ-CE 4.48Å; F660-M664 HydrophobicContact CZ-SD 4.1Å; F660-M664 WeakPolarHBondContact O-CG 3.41Å; F660-M664 PolarHBondContact O-N 3.15Å; Y661-M664 PolarHBondContact O-N 3.37Å; M664-K666 VanDerWaalsContact C-N 3.29Å; M664-K666 PolarHBondContact O-N 3.49Å; M664-V667 PolarHBondContact O-N 3.31Å; M664-L668 WeakPolarHBondContact O-CB 3.11Å; M664-L668 WeakPolarHBondContact O-CG 3.4Å; M664-L668 PolarHBondContact O-N 3.34Å
665W98Very high97.5Very high93 Ų9364.3 Ų64.335%0.35230%0.303SS..Hα-helixtrans-57.4-43.6180-168.6-111.1000111.5L564 Y567 Y661 S662 V667 L668 Q669L564-W665 HydrophobicContact CD2-CE3 3.74Å; L564-W665 HydrophobicContact CD2-CZ3 3.88Å; Y567-W665 HydrophobicContact CE2-CZ3 4.42Å; Y661-W665 WeakPolarHBondContact O-CB 3.43Å; Y661-W665 PolarHBondContact O-N 3.32Å; S662-W665 PolarHBondContact O-N 3.02Å; W665-V667 PolarHBondContact O-N 3.34Å; W665-L668 PolarHBondContact O-N 2.98Å; W665-Q669 HydrophobicContact CD2-CG 4.05Å; W665-Q669 HydrophobicContact CG-CG 4.26Å; W665-Q669 VanDerWaalsContact CH2-NE2 3.31Å; W665-Q669 HydrophobicContact CZ2-CG 4.14Å; W665-Q669 VanDerWaalsContact CZ2-NE2 3.29Å; W665-Q669 WeakPolarHBondContact O-CB 3.27Å; W665-Q669 VanDerWaalsContact O-CG 3.29Å; W665-Q669 WeakPolarHBondContact O-CG 3.4Å; W665-Q669 PolarHBondContact O-N 3.5Å
666K98.3Very high97.5Very high114 Ų11469.3 Ų69.350%0.49632%0.321SS..Hα-helixtrans-58-48.2177.2-176.3171.3176.8-173.60112.6I648 S662 A663 M664 L668 Q669 D670 Y673I648-K666 HydrophobicContact CD1-CB 4.13Å; I648-K666 HydrophobicContact CD1-CD 3.71Å; I648-K666 HydrophobicContact CD1-CG 3.99Å; S662-K666 WeakPolarHBondContact O-CB 3.44Å; S662-K666 PolarHBondContact O-N 3.43Å; A663-K666 PolarHBondContact O-N 3.06Å; M664-K666 VanDerWaalsContact C-N 3.29Å; M664-K666 PolarHBondContact O-N 3.49Å; K666-L668 VanDerWaalsContact C-N 3.35Å; K666-Q669 PolarHBondContact O-N 2.98Å; K666-D670 VanDerWaalsContact O-CB 3.31Å; K666-D670 WeakPolarHBondContact O-CB 3.34Å; K666-D670 PolarHBondContact O-N 3.27Å; K666-Y673 WeakPolarHBondContact CE-OH 3.44Å; K666-Y673 HydrophobicContact CG-CE2 4.4Å
667V98.1Very high97.4Very high9 Ų966.4 Ų66.46%0.05530%0.303CS..Hα-helixtrans-68.6-35.2179.3-178.90000111.6L605 P624 I648 A663 M664 W665 Y673L605-V667 HydrophobicContact CD1-CB 4.16Å; L605-V667 HydrophobicContact CD1-CG1 3.69Å; P624-V667 HydrophobicContact CB-CG1 3.64Å; I648-V667 HydrophobicContact CB-CG2 4.46Å; I648-V667 HydrophobicContact CD1-CG2 3.62Å; I648-V667 HydrophobicContact CG1-CG2 3.84Å; A663-V667 PolarHBondContact O-N 3Å; M664-V667 PolarHBondContact O-N 3.31Å; W665-V667 PolarHBondContact O-N 3.34Å; V667-Y673 HydrophobicContact CB-CD2 4.35Å; V667-Y673 HydrophobicContact CG1-CD2 4.24Å; V667-Y673 HydrophobicContact CG1-CG 4.22Å; V667-Y673 HydrophobicContact CG2-CD2 4.32Å; V667-Y673 HydrophobicContact CG2-CE2 4.33Å
668L97.7Very high97.3Very high31 Ų3163.8 Ų63.816%0.16230%0.302CS..Hα-helixtrans-69.5-33.6178.7-69.3167.8000113.1I536 L564 Y567 I604 L605 M664 W665 K666I536-L668 HydrophobicContact CD1-CD1 4.06Å; L564-L668 HydrophobicContact CD1-CD1 4.27Å; L564-L668 HydrophobicContact CD2-CD1 4.43Å; Y567-L668 HydrophobicContact CD2-CD1 4.36Å; Y567-L668 HydrophobicContact CE1-CD2 4.27Å; Y567-L668 HydrophobicContact CE2-CD1 3.95Å; I604-L668 HydrophobicContact CD1-CD2 3.46Å; I604-L668 VanDerWaalsContact CD1-CD2 3.46Å; I604-L668 HydrophobicContact CG1-CD2 3.94Å; L605-L668 HydrophobicContact CB-CD2 4.11Å; L605-L668 HydrophobicContact CD2-CD2 4.31Å; L605-L668 HydrophobicContact CD2-CG 4.24Å; M664-L668 WeakPolarHBondContact O-CB 3.11Å; M664-L668 WeakPolarHBondContact O-CG 3.4Å; M664-L668 PolarHBondContact O-N 3.34Å; W665-L668 PolarHBondContact O-N 2.98Å; K666-L668 VanDerWaalsContact C-N 3.35Å
669Q97.1Very high97.1Very high101 Ų10162.7 Ų62.747%0.47230%0.295SS..Hα-helixtrans-87.5-38.1-179.4-63.2-51.8-41.600113.2W665 K666 R671W665-Q669 HydrophobicContact CD2-CG 4.05Å; W665-Q669 HydrophobicContact CG-CG 4.26Å; W665-Q669 VanDerWaalsContact CH2-NE2 3.31Å; W665-Q669 HydrophobicContact CZ2-CG 4.14Å; W665-Q669 VanDerWaalsContact CZ2-NE2 3.29Å; W665-Q669 WeakPolarHBondContact O-CB 3.27Å; W665-Q669 VanDerWaalsContact O-CG 3.29Å; W665-Q669 WeakPolarHBondContact O-CG 3.4Å; W665-Q669 PolarHBondContact O-N 3.5Å; K666-Q669 PolarHBondContact O-N 2.98Å; Q669-R671 PolarHBondContact O-N 3.33Å
670D97.9Very high96.8Very high62 Ų6260.3 Ų60.333%0.33228%0.28SS..  trans-84.3101.8-176.9-177.3-5.8000111.4K666 S672 Y673K666-D670 VanDerWaalsContact O-CB 3.31Å; K666-D670 WeakPolarHBondContact O-CB 3.34Å; K666-D670 PolarHBondContact O-N 3.27Å; D670-S672 PolarHBondContact O-N 2.99Å; D670-S672 WeakPolarHBondContact OD1-CB 3.49Å; D670-S672 PolarHBondContact OD1-N 2.82Å; D670-S672 PolarHBondContact OD1-OG 2.98Å; D670-S672 PolarHBondContact OD2-OG 2.86Å; D670-Y673 HydrophobicContact CB-CD2 3.79Å; D670-Y673 HydrophobicContact CB-CE2 3.71Å; D670-Y673 WeakPolarHBondContact O-CD2 3.45Å; D670-Y673 PolarHBondContact O-N 2.96Å; D670-Y673 WeakPolarHBondContact OD2-CE2 3.29Å
671R96.9Very high96.5Very high202 Ų20261.1 Ų61.176%0.76229%0.286SS*.Hα-helixtrans-61.6-16.7178.7-66.9-174.8179.1-175.70.2113.6Q669 Y673 K674 Q675Q669-R671 PolarHBondContact O-N 3.33Å; R671-Y673 VanDerWaalsContact C-N 3.27Å; R671-Y673 PolarHBondContact O-N 2.76Å; R671-K674 PolarHBondContact O-N 3.33Å; R671-Q675 WeakPolarHBondContact O-CG 3.38Å; R671-Q675 PolarHBondContact O-N 2.8Å
672S97.2Very high96.2Very high33 Ų3360.6 Ų60.623%0.23129%0.294CS..Hα-helixtrans-62.6-33.2-178.377.50000112.4D670 Q675 R676D670-S672 PolarHBondContact O-N 2.99Å; D670-S672 WeakPolarHBondContact OD1-CB 3.49Å; D670-S672 PolarHBondContact OD1-N 2.82Å; D670-S672 PolarHBondContact OD1-OG 2.98Å; D670-S672 PolarHBondContact OD2-OG 2.86Å; S672-Q675 PolarHBondContact O-N 3.36Å; S672-R676 WeakPolarHBondContact O-CB 3.49Å; S672-R676 VanDerWaalsContact O-CG 3.24Å; S672-R676 WeakPolarHBondContact O-CG 3.36Å; S672-R676 PolarHBondContact O-N 3.34Å
673Y98.4Very high95.8Very high24 Ų2457.8 Ų57.89%0.09427%0.272CS..Hα-helixtrans-61.1-47.6174.2-63.8-76.3000111.4G645 I648 K666 V667 D670 R671 R676 I677G645-Y673 WeakPolarHBondContact O-CD1 3.25Å; I648-Y673 HydrophobicContact CG1-CE1 4.11Å; K666-Y673 WeakPolarHBondContact CE-OH 3.44Å; K666-Y673 HydrophobicContact CG-CE2 4.4Å; V667-Y673 HydrophobicContact CB-CD2 4.35Å; V667-Y673 HydrophobicContact CG1-CD2 4.24Å; V667-Y673 HydrophobicContact CG1-CG 4.22Å; V667-Y673 HydrophobicContact CG2-CD2 4.32Å; V667-Y673 HydrophobicContact CG2-CE2 4.33Å; D670-Y673 HydrophobicContact CB-CD2 3.79Å; D670-Y673 HydrophobicContact CB-CE2 3.71Å; D670-Y673 WeakPolarHBondContact O-CD2 3.45Å; D670-Y673 PolarHBondContact O-N 2.96Å; D670-Y673 WeakPolarHBondContact OD2-CE2 3.29Å; R671-Y673 VanDerWaalsContact C-N 3.27Å; R671-Y673 PolarHBondContact O-N 2.76Å; Y673-R676 PolarHBondContact O-N 2.83Å; Y673-I677 PolarHBondContact O-N 3.45Å; Y673-I677 VanDerWaalsContact O-N 3.13Å
674K98Very high95.2Very high87 Ų8758.2 Ų58.238%0.37827%0.274SS..Hα-helixtrans-64.7-42176.7-176.566.5176.9-1710112A622 P624 R671 I677 A678A622-K674 VanDerWaalsContact O-CD 3.24Å; A622-K674 WeakPolarHBondContact O-CD 3.28Å; A622-K674 VanDerWaalsContact O-CE 3.29Å; A622-K674 WeakPolarHBondContact O-CE 3.43Å; A622-K674 PolarHBondContact O-NZ 2.9Å; P624-K674 HydrophobicContact CG-CB 3.89Å; P624-K674 HydrophobicContact CG-CD 3.99Å; R671-K674 PolarHBondContact O-N 3.33Å; K674-I677 HydrophobicContact CD-CG2 4.47Å; K674-I677 WeakPolarHBondContact O-CG2 3.29Å; K674-A678 WeakPolarHBondContact O-CB 3.28Å; K674-A678 PolarHBondContact O-N 2.9Å
675Q96.4Very high94.6Very high113 Ų11361.7 Ų61.753%0.52830%0.298SS..Hα-helixtrans-64.3-41.2178.5-71171.9-4.800112.1R671 S672 K679R671-Q675 WeakPolarHBondContact O-CG 3.38Å; R671-Q675 PolarHBondContact O-N 2.8Å; S672-Q675 PolarHBondContact O-N 3.36Å; Q675-K679 WeakPolarHBondContact O-CG 3.46Å; Q675-K679 PolarHBondContact O-N 3.13Å; Q675-K679 VanDerWaalsContact O-N 3.13Å
676R94.5Very high94.1Very high119 Ų11958.9 Ų58.945%0.44929%0.29SS..Hα-helixtrans-67.4-45.5179.4-73.5170.6-172.6-76.91.7112H644 G645 F646 S672 Y673 K679 L680H644-R676 WeakPolarHBondContact O-CD 3.35Å; G645-R676 WeakPolarHBondContact O-CD 3.41Å; F646-R676 HydrophobicContact CB-CB 4.38Å; S672-R676 WeakPolarHBondContact O-CB 3.49Å; S672-R676 VanDerWaalsContact O-CG 3.24Å; S672-R676 WeakPolarHBondContact O-CG 3.36Å; S672-R676 PolarHBondContact O-N 3.34Å; Y673-R676 PolarHBondContact O-N 2.83Å; R676-K679 PolarHBondContact O-N 3.02Å; R676-L680 PolarHBondContact O-N 3Å; R676-L680 VanDerWaalsContact O-N 3.17Å
677I95.4Very high93.4Very high0 Ų057.4 Ų57.40%029%0.287CS..Hα-helixtrans-69.3-34.2177.4-155.8173.1000112.7V619 A622 V623 P624 M625 F646 Y673 K674 K679 L680 S681V619-I677 HydrophobicContact CB-CD1 4.45Å; V619-I677 HydrophobicContact CB-CG1 4.42Å; V619-I677 HydrophobicContact CG1-CG1 4.19Å; V619-I677 HydrophobicContact CG2-CD1 4.14Å; V619-I677 HydrophobicContact CG2-CG1 4.34Å; A622-I677 VanDerWaalsContact C-CG2 3.47Å; A622-I677 HydrophobicContact CB-CG2 4.15Å; A622-I677 VanDerWaalsContact O-CG2 3.26Å; A622-I677 WeakPolarHBondContact O-CG2 3.44Å; V623-I677 WeakPolarHBondContact O-CD1 3.49Å; P624-I677 HydrophobicContact CG-CG2 4.17Å; M625-I677 HydrophobicContact CE-CD1 4.21Å; F646-I677 HydrophobicContact CB-CB 3.67Å; F646-I677 HydrophobicContact CB-CD1 4.45Å; F646-I677 HydrophobicContact CB-CG1 4.23Å; F646-I677 HydrophobicContact CD2-CB 4.44Å; F646-I677 HydrophobicContact CD2-CD1 3.75Å; F646-I677 HydrophobicContact CD2-CG1 4.06Å; F646-I677 HydrophobicContact CE2-CD1 4.27Å; F646-I677 HydrophobicContact CG-CB 4.05Å; F646-I677 HydrophobicContact CG-CD1 4.23Å; F646-I677 HydrophobicContact CG-CG1 4.07Å; Y673-I677 PolarHBondContact O-N 3.45Å; Y673-I677 VanDerWaalsContact O-N 3.13Å; K674-I677 HydrophobicContact CD-CG2 4.47Å; K674-I677 WeakPolarHBondContact O-CG2 3.29Å; I677-K679 VanDerWaalsContact C-N 3.32Å; I677-K679 PolarHBondContact O-N 2.96Å; I677-L680 PolarHBondContact O-N 2.95Å; I677-S681 WeakPolarHBondContact O-CB 3.42Å; I677-S681 PolarHBondContact O-N 3.2Å
678A95.4Very high92.8Very high40 Ų4059.8 Ų59.833%0.33130%0.302SS..Hα-helixtrans-64.5-37175.500000112.1A622 K674 A682A622-A678 HydrophobicContact CB-CB 4.16Å; K674-A678 WeakPolarHBondContact O-CB 3.28Å; K674-A678 PolarHBondContact O-N 2.9Å; A678-A682 WeakPolarHBondContact O-CB 3.37Å; A678-A682 PolarHBondContact O-N 2.89Å
679K92.2Very high92.1Very high90 Ų9060.1 Ų60.139%0.39130%0.304SS..Hα-helixtrans-62.3-47172-73.4172.6-178.3-178.60111.4Q675 R676 I677 A682 M683Q675-K679 WeakPolarHBondContact O-CG 3.46Å; Q675-K679 PolarHBondContact O-N 3.13Å; Q675-K679 VanDerWaalsContact O-N 3.13Å; R676-K679 PolarHBondContact O-N 3.02Å; I677-K679 VanDerWaalsContact C-N 3.32Å; I677-K679 PolarHBondContact O-N 2.96Å; K679-A682 PolarHBondContact O-N 3.45Å; K679-M683 HydrophobicContact CB-CE 4.32Å; K679-M683 WeakPolarHBondContact O-CG 3.39Å; K679-M683 PolarHBondContact O-N 3.14Å
680L90.4Very high91.4Very high10 Ų1058.6 Ų58.65%0.05230%0.298CS..Hα-helixtrans-64.7-41.9177.9-72.7166.8000112.4L496 V619 H644 F646 R676 I677 A682 M683 L684L496-L680 HydrophobicContact CD2-CB 4.31Å; L496-L680 HydrophobicContact CD2-CD1 3.7Å; L496-L680 HydrophobicContact CD2-CD2 4.02Å; L496-L680 HydrophobicContact CD2-CG 4.23Å; V619-L680 HydrophobicContact CG1-CB 4.24Å; H644-L680 HydrophobicContact CB-CD1 3.97Å; F646-L680 HydrophobicContact CD1-CD1 3.5Å; F646-L680 HydrophobicContact CE1-CD1 3.41Å; F646-L680 VanDerWaalsContact CE1-CD1 3.41Å; R676-L680 PolarHBondContact O-N 3Å; R676-L680 VanDerWaalsContact O-N 3.17Å; I677-L680 PolarHBondContact O-N 2.95Å; L680-A682 VanDerWaalsContact C-N 3.33Å; L680-A682 PolarHBondContact O-N 3.29Å; L680-M683 PolarHBondContact O-N 3.34Å; L680-L684 WeakPolarHBondContact O-CB 3.48Å; L680-L684 VanDerWaalsContact O-CG 3.3Å; L680-L684 WeakPolarHBondContact O-CG 3.49Å; L680-L684 PolarHBondContact O-N 2.95Å
681S92.7Very high90.5Very high18 Ų1857.1 Ų57.113%0.12629%0.29CS..Hα-helixtrans-55.3-47.4172.5173.10000111.8V619 C620 I677 M683 L684 S685V619-S681 WeakPolarHBondContact O-CB 3.29Å; C620-S681 PolarHBondContact O-OG 3.23Å; I677-S681 WeakPolarHBondContact O-CB 3.42Å; I677-S681 PolarHBondContact O-N 3.2Å; S681-M683 VanDerWaalsContact C-N 3.35Å; S681-M683 PolarHBondContact O-N 3.43Å; S681-L684 PolarHBondContact O-N 3.13Å; S681-S685 WeakPolarHBondContact O-CB 3.42Å; S681-S685 PolarHBondContact O-N 3.5Å; S681-S685 PolarHBondContact O-OG 2.71Å
682A92Very high89.8Confident46 Ų4652 Ų5238%0.3828%0.281SS..Hα-helixtrans-63.8-40.2179.100000112.1A678 K679 L680 S685 D686A678-A682 WeakPolarHBondContact O-CB 3.37Å; A678-A682 PolarHBondContact O-N 2.89Å; K679-A682 PolarHBondContact O-N 3.45Å; L680-A682 VanDerWaalsContact C-N 3.33Å; L680-A682 PolarHBondContact O-N 3.29Å; A682-S685 PolarHBondContact O-N 2.59Å; A682-D686 WeakPolarHBondContact O-CB 3.2Å; A682-D686 PolarHBondContact O-N 2.9Å
683M88.4Confident89.2Confident13 Ų1357.4 Ų57.46%0.06430%0.3CS..Hα-helixtrans-66.5-43.4174.9-70.1-179.7-151.900112.1F446 H450 M495 K679 L680 S681 S685 D686F446-M683 HydrophobicContact CE2-CB 4.46Å; F446-M683 HydrophobicContact CZ-CB 3.92Å; F446-M683 HydrophobicContact CZ-CG 4.08Å; H450-M683 HydrophobicContact CB-CE 4.14Å; H450-M683 HydrophobicContact CB-CG 3.95Å; H450-M683 HydrophobicContact CB-SD 4.37Å; M495-M683 HydrophobicContact CE-CB 4.16Å; M495-M683 HydrophobicContact SD-CB 3.5Å; M495-M683 VanDerWaalsContact SD-CB 3.5Å; M495-M683 HydrophobicContact SD-CG 4.21Å; M495-M683 HydrophobicContact SD-SD 3.94Å; K679-M683 HydrophobicContact CB-CE 4.32Å; K679-M683 WeakPolarHBondContact O-CG 3.39Å; K679-M683 PolarHBondContact O-N 3.14Å; L680-M683 PolarHBondContact O-N 3.34Å; S681-M683 VanDerWaalsContact C-N 3.35Å; S681-M683 PolarHBondContact O-N 3.43Å; M683-S685 PolarHBondContact O-N 3.48Å; M683-D686 PolarHBondContact O-N 3.42Å
684L85.8Confident88.6Confident17 Ų1758.4 Ų58.49%0.08931%0.305CS..Hα-helixtrans-66.4-24.2177.2-73.1176.2000113.3P493 M495 L496 V619 L680 S681 N687P493-L684 HydrophobicContact CB-CD2 3.48Å; P493-L684 VanDerWaalsContact CB-CD2 3.48Å; P493-L684 HydrophobicContact CG-CD1 4.28Å; P493-L684 HydrophobicContact CG-CD2 4.04Å; M495-L684 HydrophobicContact CB-CD2 4.31Å; L496-L684 HydrophobicContact CD1-CD1 4.44Å; V619-L684 HydrophobicContact CB-CD1 4.39Å; V619-L684 HydrophobicContact CG1-CD1 3.5Å; L680-L684 WeakPolarHBondContact O-CB 3.48Å; L680-L684 VanDerWaalsContact O-CG 3.3Å; L680-L684 WeakPolarHBondContact O-CG 3.49Å; L680-L684 PolarHBondContact O-N 2.95Å; S681-L684 PolarHBondContact O-N 3.13Å; L684-N687 PolarHBondContact O-ND2 3Å
685S86.5Confident88Confident74 Ų7454.4 Ų54.452%0.51729%0.289SS..Hα-helixtrans-86.6-16.5176.5-55.70000112.5S681 A682 M683 N687S681-S685 WeakPolarHBondContact O-CB 3.42Å; S681-S685 PolarHBondContact O-N 3.5Å; S681-S685 PolarHBondContact O-OG 2.71Å; A682-S685 PolarHBondContact O-N 2.59Å; M683-S685 PolarHBondContact O-N 3.48Å; S685-N687 PolarHBondContact O-N 3.16Å
686D88Confident87.7Confident34 Ų3452.3 Ų52.318%0.18229%0.287CS..  trans-91.673179.7-169.9-8.4000109.4F442 F446 R449 H450 A682 M683F442-D686 WeakPolarHBondContact CZ-O 3.33Å; F446-D686 HydrophobicContact CD2-CB 4.11Å; F446-D686 HydrophobicContact CE2-CB 3.91Å; F446-D686 WeakPolarHBondContact CE2-O 3.35Å; R449-D686 IonicContact CZ-OD1 2.67Å; R449-D686 IonicContact CZ-OD2 2.85Å; R449-D686 IonicContact NE-OD1 2.73Å; R449-D686 IonicContact NE-OD2 2.81Å; R449-D686 PolarHBondContact NE-OD2 2.88Å; R449-D686 IonicContact NH2-OD1 2.59Å; R449-D686 PolarHBondContact NH2-OD1 3.37Å; R449-D686 IonicContact NH2-OD2 3.44Å; R449-D686 PolarHBondContact NH2-OD2 3.31Å; H450-D686 IonicContact CD2-OD2 3.66Å; H450-D686 PolarHBondContact CD2-OD2 3.05Å; H450-D686 IonicContact NE2-OD2 3.78Å; H450-D686 PolarHBondContact NE2-OD2 3.26Å; A682-D686 WeakPolarHBondContact O-CB 3.2Å; A682-D686 PolarHBondContact O-N 2.9Å; M683-D686 PolarHBondContact O-N 3.42Å
687N83.4Confident87.5Confident82 Ų8247.9 Ų47.944%0.43927%0.271SS..  trans-108.5145.2177.7-61.9-53.6000111L684 S685L684-N687 PolarHBondContact O-ND2 3Å; S685-N687 PolarHBondContact O-N 3.16Å
688V84.7Confident87.2Confident60 Ų6049.9 Ų49.936%0.36428%0.278SS..SBendtrans-79-32.8176.462.70000113.1I434 F442I434-V688 HydrophobicContact CD1-CG2 3.31Å; F442-V688 HydrophobicContact CB-CB 4.45Å; F442-V688 HydrophobicContact CB-CG2 4.18Å; F442-V688 HydrophobicContact CD1-CB 3.68Å; F442-V688 HydrophobicContact CD1-CG1 4.02Å; F442-V688 HydrophobicContact CD1-CG2 4.31Å; F442-V688 HydrophobicContact CD2-CB 3.66Å; F442-V688 HydrophobicContact CD2-CG2 3.89Å; F442-V688 HydrophobicContact CE1-CB 3.76Å; F442-V688 HydrophobicContact CE1-CG1 4.08Å; F442-V688 HydrophobicContact CE2-CB 3.73Å; F442-V688 HydrophobicContact CE2-CG2 4.39Å; F442-V688 HydrophobicContact CG-CB 3.63Å; F442-V688 HydrophobicContact CG-CG1 4.4Å; F442-V688 HydrophobicContact CG-CG2 3.84Å; F442-V688 HydrophobicContact CZ-CB 3.78Å
689I83.5Confident86.9Confident38 Ų3852.6 Ų52.620%0.19529%0.286CS..SBendtrans-135.5141.7-175.8-60.5150.2000108.7L433 I434 E691 K694L433-I689 HydrophobicContact CD1-CG2 4.44Å; L433-I689 HydrophobicContact CD2-CD1 3.8Å; L433-I689 HydrophobicContact CD2-CG2 3.98Å; L433-I689 HydrophobicContact CG-CD1 3.83Å; L433-I689 HydrophobicContact CG-CG1 4.49Å; L433-I689 HydrophobicContact CG-CG2 4.32Å; I434-I689 HydrophobicContact CB-CD1 4.01Å; I434-I689 HydrophobicContact CD1-CD1 4.41Å; I434-I689 HydrophobicContact CG2-CD1 3.85Å; I689-E691 PolarHBondContact O-N 3.31Å; I689-K694 HydrophobicContact CG2-CB 4.28Å
690D82.7Confident87Confident68 Ų6850.1 Ų50.136%0.36428%0.28SS..  trans-62.3124.9168.7177.9-91.1000110.6T692 K693 K694D690-T692 VanDerWaalsContact C-N 3.28Å; D690-T692 PolarHBondContact O-N 3.43Å; D690-T692 WeakPolarHBondContact OD1-CA 3.14Å; D690-T692 VanDerWaalsContact OD1-CB 3.23Å; D690-T692 WeakPolarHBondContact OD1-CB 3.49Å; D690-T692 PolarHBondContact OD1-N 3.24Å; D690-K693 HydrophobicContact CB-CB 4.13Å; D690-K693 HydrophobicContact CB-CD 4.07Å; D690-K693 HydrophobicContact CB-CG 4Å; D690-K693 WeakPolarHBondContact O-CB 3.38Å; D690-K693 PolarHBondContact O-N 2.86Å; D690-K693 VanDerWaalsContact O-N 3.08Å; D690-K693 PolarHBondContact OD1-N 3.42Å; D690-K694 PolarHBondContact O-N 3.31Å
691E78.9Confident87.1Confident32 Ų3249.7 Ų49.715%0.1528%0.278CS..Hα-helixtrans-67.6-28.8-172.2-73.1-81.3144.100112.3L509 D510 I689 K694 G695L509-E691 WeakPolarHBondContact CD2-O 3.48Å; D510-E691 HydrophobicContact CB-CB 3.9Å; D510-E691 HydrophobicContact CB-CG 3.63Å; D510-E691 PolarHBondContact N-OE2 3.06Å; D510-E691 WeakPolarHBondContact O-CB 3.36Å; I689-E691 PolarHBondContact O-N 3.31Å; E691-K694 VanDerWaalsContact CD-NZ 3.33Å; E691-K694 WeakPolarHBondContact O-CB 3.36Å; E691-K694 PolarHBondContact O-N 2.72Å; E691-K694 WeakPolarHBondContact OE1-CD 3.43Å; E691-K694 IonicContact OE1-NZ 3Å; E691-K694 PolarHBondContact OE1-NZ 3.37Å; E691-K694 WeakPolarHBondContact OE2-CD 3.22Å; E691-K694 IonicContact OE2-NZ 3.21Å; E691-K694 PolarHBondContact OE2-NZ 3.07Å; E691-G695 PolarHBondContact O-N 2.85Å
692T81.8Confident87Confident95 Ų9552.6 Ų52.658%0.58329%0.287SS*.Hα-helixtrans-67.2-42.6172.1-48.10000111D690 K694 G695 S696D690-T692 VanDerWaalsContact C-N 3.28Å; D690-T692 PolarHBondContact O-N 3.43Å; D690-T692 WeakPolarHBondContact OD1-CA 3.14Å; D690-T692 VanDerWaalsContact OD1-CB 3.23Å; D690-T692 WeakPolarHBondContact OD1-CB 3.49Å; D690-T692 PolarHBondContact OD1-N 3.24Å; T692-K694 VanDerWaalsContact C-N 3.33Å; T692-K694 PolarHBondContact O-N 3.36Å; T692-G695 PolarHBondContact O-N 3.2Å; T692-S696 PolarHBondContact O-N 2.95Å
693K85.3Confident87.1Confident145 Ų14556.3 Ų56.363%0.6330%0.3SS*.Hα-helixtrans-62.4-39.1173.8-69.5-174.2-178.4179.10112.1D690 G695 S696 F697D690-K693 HydrophobicContact CB-CB 4.13Å; D690-K693 HydrophobicContact CB-CD 4.07Å; D690-K693 HydrophobicContact CB-CG 4Å; D690-K693 WeakPolarHBondContact O-CB 3.38Å; D690-K693 PolarHBondContact O-N 2.86Å; D690-K693 VanDerWaalsContact O-N 3.08Å; D690-K693 PolarHBondContact OD1-N 3.42Å; K693-G695 VanDerWaalsContact C-N 3.35Å; K693-S696 PolarHBondContact O-N 2.86Å; K693-F697 WeakPolarHBondContact O-CB 3.48Å; K693-F697 PolarHBondContact O-N 3.47Å
694K85.3Confident87.4Confident45 Ų4561.3 Ų61.320%0.19632%0.318CS..Hα-helixtrans-60.2-44174.2178.8-170.6175.5-166.60111.6L433 S508 L509 I689 D690 E691 T692 F697 W698L433-K694 HydrophobicContact CD2-CB 3.87Å; L433-K694 HydrophobicContact CD2-CG 3.89Å; S508-K694 PolarHBondContact O-NZ 3.13Å; L509-K694 HydrophobicContact CD2-CB 4.37Å; L509-K694 HydrophobicContact CD2-CD 4.24Å; L509-K694 HydrophobicContact CD2-CG 4.24Å; I689-K694 HydrophobicContact CG2-CB 4.28Å; D690-K694 PolarHBondContact O-N 3.31Å; E691-K694 VanDerWaalsContact CD-NZ 3.33Å; E691-K694 WeakPolarHBondContact O-CB 3.36Å; E691-K694 PolarHBondContact O-N 2.72Å; E691-K694 WeakPolarHBondContact OE1-CD 3.43Å; E691-K694 IonicContact OE1-NZ 3Å; E691-K694 PolarHBondContact OE1-NZ 3.37Å; E691-K694 WeakPolarHBondContact OE2-CD 3.22Å; E691-K694 IonicContact OE2-NZ 3.21Å; E691-K694 PolarHBondContact OE2-NZ 3.07Å; T692-K694 VanDerWaalsContact C-N 3.33Å; T692-K694 PolarHBondContact O-N 3.36Å; K694-F697 PolarHBondContact O-N 3.16Å; K694-W698 PolarHBondContact O-N 3.23Å; K694-W698 VanDerWaalsContact O-N 3.14Å
695G85.2Confident87.8Confident3 Ų361.3 Ų61.33%0.03132%0.317CS..Hα-helixtrans-61.4-50.3174.900000113L509 E691 T692 K693 F697 W698 I699L509-G695 VanDerWaalsContact CD1-CA 3.42Å; E691-G695 PolarHBondContact O-N 2.85Å; T692-G695 PolarHBondContact O-N 3.2Å; K693-G695 VanDerWaalsContact C-N 3.35Å; G695-F697 VanDerWaalsContact C-N 3.29Å; G695-F697 PolarHBondContact O-N 2.95Å; G695-W698 PolarHBondContact O-N 2.57Å; G695-I699 WeakPolarHBondContact O-CG1 3.42Å; G695-I699 PolarHBondContact O-N 3.05Å; G695-I699 VanDerWaalsContact O-N 3.11Å
696S89.5Confident87.9Confident70 Ų7061.3 Ų61.349%0.4932%0.315SS..Hα-helixtrans-57.9-41.6176.3179.80000112.3T692 K693 S700T692-S696 PolarHBondContact O-N 2.95Å; K693-S696 PolarHBondContact O-N 2.86Å; S696-S700 WeakPolarHBondContact O-CB 3.47Å; S696-S700 PolarHBondContact O-N 2.9Å; S696-S700 PolarHBondContact O-OG 2.76Å
697F91.4Very high87.8Confident26 Ų2662.5 Ų62.511%0.11432%0.32CS..Hα-helixtrans-59-50.1176.8172.4-91.3000111.8D431 L433 K693 K694 G695 S700 F701D431-F697 WeakPolarHBondContact O-CZ 3.41Å; D431-F697 WeakPolarHBondContact OD1-CE2 3.4Å; L433-F697 HydrophobicContact CB-CD1 3.77Å; L433-F697 HydrophobicContact CB-CD2 4.12Å; L433-F697 HydrophobicContact CB-CE1 3.81Å; L433-F697 HydrophobicContact CB-CE2 4.14Å; L433-F697 HydrophobicContact CB-CG 3.93Å; L433-F697 HydrophobicContact CB-CZ 4Å; L433-F697 HydrophobicContact CD1-CB 3.83Å; L433-F697 HydrophobicContact CD1-CD1 4.41Å; L433-F697 HydrophobicContact CD1-CD2 3.85Å; L433-F697 HydrophobicContact CD1-CG 3.75Å; L433-F697 HydrophobicContact CD2-CB 4.27Å; L433-F697 HydrophobicContact CD2-CD1 4.21Å; L433-F697 HydrophobicContact CD2-CG 4.26Å; L433-F697 HydrophobicContact CG-CD1 4.36Å; L433-F697 HydrophobicContact CG-CG 4.2Å; L433-F697 VanDerWaalsContact N-CZ 3.35Å; K693-F697 WeakPolarHBondContact O-CB 3.48Å; K693-F697 PolarHBondContact O-N 3.47Å; K694-F697 PolarHBondContact O-N 3.16Å; G695-F697 VanDerWaalsContact C-N 3.29Å; G695-F697 PolarHBondContact O-N 2.95Å; F697-S700 CarbonylContact O-C 3.48Å; F697-S700 PolarHBondContact O-N 3.19Å; F697-F701 HydrophobicContact CE1-CB 4.22Å; F697-F701 HydrophobicContact CE1-CD2 4.25Å; F697-F701 HydrophobicContact CZ-CB 4.5Å; F697-F701 HydrophobicContact CZ-CD2 4.12Å; F697-F701 WeakPolarHBondContact O-CB 3.46Å; F697-F701 PolarHBondContact O-N 3.43Å
698W88.5Confident87.8Confident42 Ų4258.7 Ų58.716%0.15930%0.299CS..Hα-helixtrans-69.2-35.1-176.7-76.3118.3000113.4M240 F507 K694 G695 S700 F701 Y702M240-W698 HydrophobicContact CE-CH2 3.78Å; M240-W698 HydrophobicContact CE-CZ3 3.77Å; F507-W698 AromaticContact CD1-CD1 3.84Å; F507-W698 HydrophobicContact CD1-CG 4.2Å; F507-W698 HydrophobicContact CE1-CB 3.59Å; F507-W698 AromaticContact CE1-CD1 3.33Å; F507-W698 AromaticContact CE1-CD2 4Å; F507-W698 HydrophobicContact CE1-CD2 4Å; F507-W698 AromaticContact CE1-CG 3.35Å; F507-W698 HydrophobicContact CE1-CG 3.35Å; F507-W698 AromaticContact CE1-NE1 3.94Å; F507-W698 HydrophobicContact CE2-CB 4.41Å; F507-W698 AromaticContact CE2-CD1 3.91Å; F507-W698 HydrophobicContact CE2-CG 4.42Å; F507-W698 HydrophobicContact CZ-CB 3.37Å; F507-W698 AromaticContact CZ-CD1 3.4Å; F507-W698 VanDerWaalsContact CZ-CD1 3.4Å; F507-W698 AromaticContact CZ-CG 3.52Å; F507-W698 HydrophobicContact CZ-CG 3.52Å; K694-W698 PolarHBondContact O-N 3.23Å; K694-W698 VanDerWaalsContact O-N 3.14Å; G695-W698 PolarHBondContact O-N 2.57Å; W698-S700 VanDerWaalsContact C-N 3.33Å; W698-F701 HydrophobicContact CE3-CB 4.11Å; W698-F701 AromaticContact CE3-CD1 4Å; W698-F701 HydrophobicContact CE3-CD1 4Å; W698-F701 AromaticContact CE3-CG 3.99Å; W698-F701 HydrophobicContact CE3-CG 3.99Å; W698-F701 AromaticContact CZ3-CD1 3.99Å; W698-F701 HydrophobicContact CZ3-CD1 3.99Å; W698-F701 HydrophobicContact CZ3-CD2 4.3Å; W698-F701 HydrophobicContact CZ3-CE1 4.2Å; W698-F701 HydrophobicContact CZ3-CE2 4.49Å; W698-F701 HydrophobicContact CZ3-CG 4.05Å; W698-F701 HydrophobicContact CZ3-CZ 4.45Å; W698-F701 PolarHBondContact O-N 3.46Å; W698-Y702 PolarHBondContact O-N 3.33Å
699I89.4Confident87.6Confident96 Ų9655.9 Ų55.949%0.49228%0.283SS..Hα-helixtrans-60-49.1170.3-67.4167.8000109.2G695 F701 Y702 L703G695-I699 WeakPolarHBondContact O-CG1 3.42Å; G695-I699 PolarHBondContact O-N 3.05Å; G695-I699 VanDerWaalsContact O-N 3.11Å; I699-F701 VanDerWaalsContact C-N 3.34Å; I699-F701 PolarHBondContact O-N 2.83Å; I699-Y702 PolarHBondContact O-N 3.06Å; I699-L703 HydrophobicContact CG2-CD1 4.39Å; I699-L703 WeakPolarHBondContact O-CG 3.41Å; I699-L703 PolarHBondContact O-N 3.25Å; I699-L703 VanDerWaalsContact O-N 3.12Å
700S93.8Very high87.3Confident38 Ų3857.3 Ų57.327%0.26630%0.296SS..Hα-helixtrans-66.2-36179.6-54.60000112.5S696 F697 W698 L703 R704S696-S700 WeakPolarHBondContact O-CB 3.47Å; S696-S700 PolarHBondContact O-N 2.9Å; S696-S700 PolarHBondContact O-OG 2.76Å; F697-S700 CarbonylContact O-C 3.48Å; F697-S700 PolarHBondContact O-N 3.19Å; W698-S700 VanDerWaalsContact C-N 3.33Å; S700-L703 PolarHBondContact O-N 3.27Å; S700-R704 WeakPolarHBondContact O-CG 3.37Å; S700-R704 PolarHBondContact O-N 3.01Å
701F92.3Very high87.1Confident1 Ų156.1 Ų56.10%0.00429%0.288CS..Hα-helixtrans-60.1-46.2175.1176.7-84.5000110.4M240 M428 D431 F697 W698 I699 L703 R704 H705 M712M240-F701 HydrophobicContact CE-CE1 4.19Å; M240-F701 HydrophobicContact CE-CE2 4.21Å; M240-F701 HydrophobicContact CE-CZ 3.66Å; M240-F701 HydrophobicContact SD-CZ 4Å; M428-F701 HydrophobicContact CB-CZ 4.14Å; M428-F701 HydrophobicContact CG-CZ 4.35Å; M428-F701 WeakPolarHBondContact O-CE2 3.49Å; D431-F701 HydrophobicContact CB-CD2 4.08Å; D431-F701 HydrophobicContact CB-CE2 3.93Å; D431-F701 WeakPolarHBondContact O-CD2 3.34Å; D431-F701 WeakPolarHBondContact O-CE2 3.49Å; F697-F701 HydrophobicContact CE1-CB 4.22Å; F697-F701 HydrophobicContact CE1-CD2 4.25Å; F697-F701 HydrophobicContact CZ-CB 4.5Å; F697-F701 HydrophobicContact CZ-CD2 4.12Å; F697-F701 WeakPolarHBondContact O-CB 3.46Å; F697-F701 PolarHBondContact O-N 3.43Å; W698-F701 HydrophobicContact CE3-CB 4.11Å; W698-F701 AromaticContact CE3-CD1 4Å; W698-F701 HydrophobicContact CE3-CD1 4Å; W698-F701 AromaticContact CE3-CG 3.99Å; W698-F701 HydrophobicContact CE3-CG 3.99Å; W698-F701 AromaticContact CZ3-CD1 3.99Å; W698-F701 HydrophobicContact CZ3-CD1 3.99Å; W698-F701 HydrophobicContact CZ3-CD2 4.3Å; W698-F701 HydrophobicContact CZ3-CE1 4.2Å; W698-F701 HydrophobicContact CZ3-CE2 4.49Å; W698-F701 HydrophobicContact CZ3-CG 4.05Å; W698-F701 HydrophobicContact CZ3-CZ 4.45Å; W698-F701 PolarHBondContact O-N 3.46Å; I699-F701 VanDerWaalsContact C-N 3.34Å; I699-F701 PolarHBondContact O-N 2.83Å; F701-L703 VanDerWaalsContact C-N 3.32Å; F701-L703 PolarHBondContact O-N 3.24Å; F701-R704 PolarHBondContact O-N 2.92Å; F701-H705 AromaticContact CD2-CD2 3.81Å; F701-H705 HydrophobicContact CE1-CB 4.48Å; F701-H705 AromaticContact CE2-CD2 3.72Å; F701-H705 AromaticContact CZ-CD2 3.93Å; F701-H705 PolarHBondContact O-CD2 3.03Å; F701-H705 VanDerWaalsContact O-CD2 3.31Å; F701-H705 PolarHBondContact O-N 3.34Å; F701-M712 HydrophobicContact CE1-CE 4.23Å
702Y90.2Very high87.1Confident80 Ų8054.7 Ų54.731%0.31428%0.282SS..Hα-helixtrans-62.2-40.8176.1177-104.3000111.9L484 W698 I699 R704 H705 P706L484-Y702 HydrophobicContact CD2-CD2 4.03Å; L484-Y702 HydrophobicContact CD2-CE2 3.13Å; L484-Y702 WeakPolarHBondContact CD2-OH 3.25Å; W698-Y702 PolarHBondContact O-N 3.33Å; I699-Y702 PolarHBondContact O-N 3.06Å; Y702-R704 VanDerWaalsContact C-N 3.34Å; Y702-R704 PolarHBondContact O-N 3.08Å; Y702-H705 CarbonylContact O-C 3.55Å; Y702-H705 PolarHBondContact O-N 2.95Å; Y702-P706 WeakPolarHBondContact CE2-O 3.49Å; Y702-P706 WeakPolarHBondContact O-CA 3.28Å; Y702-P706 VanDerWaalsContact O-N 3.11Å
703L94.2Very high87Confident124 Ų12454.6 Ų54.665%0.64927%0.271SS*.Hα-helixtrans-64.7-37.1176-65.8174.7000112.5I699 S700 F701I699-L703 HydrophobicContact CG2-CD1 4.39Å; I699-L703 WeakPolarHBondContact O-CG 3.41Å; I699-L703 PolarHBondContact O-N 3.25Å; I699-L703 VanDerWaalsContact O-N 3.12Å; S700-L703 PolarHBondContact O-N 3.27Å; F701-L703 VanDerWaalsContact C-N 3.32Å; F701-L703 PolarHBondContact O-N 3.24Å
704R95Very high86.8Confident117 Ų11749.8 Ų49.844%0.44225%0.251SS..Hα-helixtrans-71-32173.8-70.1-172.5-58.1-91.46112.5D431 S700 F701 Y702D431-R704 VanDerWaalsContact CG-NH2 3.27Å; D431-R704 IonicContact OD1-CZ 3.78Å; D431-R704 IonicContact OD1-NE 3.46Å; D431-R704 IonicContact OD1-NH2 2.61Å; D431-R704 PolarHBondContact OD1-NH2 3.2Å; D431-R704 IonicContact OD2-CZ 2.87Å; D431-R704 VanDerWaalsContact OD2-CZ 3.26Å; D431-R704 IonicContact OD2-NE 2.78Å; D431-R704 PolarHBondContact OD2-NE 3.14Å; D431-R704 IonicContact OD2-NH2 2.76Å; D431-R704 PolarHBondContact OD2-NH2 3.22Å; S700-R704 WeakPolarHBondContact O-CG 3.37Å; S700-R704 PolarHBondContact O-N 3.01Å; F701-R704 PolarHBondContact O-N 2.92Å; Y702-R704 VanDerWaalsContact C-N 3.34Å; Y702-R704 PolarHBondContact O-N 3.08Å
705H93.3Very high86.6Confident18 Ų1850.5 Ų50.58%0.08326%0.255CS..  trans-129.671.5-176.7-52.3-75.4000112.2M428 D431 F701 Y702 Q707 S708M428-H705 HydrophobicContact CG-CB 3.69Å; M428-H705 WeakPolarHBondContact CG-ND1 3.22Å; M428-H705 HydrophobicContact SD-CB 4.08Å; D431-H705 IonicContact OD2-CD2 2.81Å; D431-H705 PolarHBondContact OD2-CD2 3.43Å; D431-H705 IonicContact OD2-NE2 2.8Å; D431-H705 PolarHBondContact OD2-NE2 3.15Å; F701-H705 AromaticContact CD2-CD2 3.81Å; F701-H705 HydrophobicContact CE1-CB 4.48Å; F701-H705 AromaticContact CE2-CD2 3.72Å; F701-H705 AromaticContact CZ-CD2 3.93Å; F701-H705 PolarHBondContact O-CD2 3.03Å; F701-H705 VanDerWaalsContact O-CD2 3.31Å; F701-H705 PolarHBondContact O-N 3.34Å; Y702-H705 CarbonylContact O-C 3.55Å; Y702-H705 PolarHBondContact O-N 2.95Å; H705-Q707 PolarHBondContact O-N 2.93Å; H705-Q707 VanDerWaalsContact O-N 3.11Å; H705-S708 WeakPolarHBondContact O-CB 3.39Å; H705-S708 PolarHBondContact O-N 2.61Å; H705-S708 PolarHBondContact O-OG 3.46Å
706P89.8Confident86.4Confident73 Ų7350.9 Ų50.947%0.47426%0.259SS..THydrogen-bonded Turntrans-59.7-30.1-173.3-26.535.6000114.6Y702 S708Y702-P706 WeakPolarHBondContact CE2-O 3.49Å; Y702-P706 WeakPolarHBondContact O-CA 3.28Å; Y702-P706 VanDerWaalsContact O-N 3.11Å; P706-S708 PolarHBondContact O-N 2.8Å
707Q84.9Confident85.8Confident60 Ų6050.3 Ų50.328%0.2825%0.249SC..THydrogen-bonded Turntrans-69.8-16.3176.171.3-75.5-6.100113.9M428 H705 G709 S710M428-Q707 HydrophobicContact SD-CG 4.25Å; H705-Q707 PolarHBondContact O-N 2.93Å; H705-Q707 VanDerWaalsContact O-N 3.11Å; Q707-G709 PolarHBondContact O-N 3.5Å; Q707-G709 VanDerWaalsContact O-N 3.16Å; Q707-S710 PolarHBondContact O-N 3.16Å; Q707-S710 PolarHBondContact O-OG 3.46Å
708S85.1Confident85.3Confident1 Ų152.7 Ų52.71%0.00727%0.266CS..Hα-helixtrans-56.6-33.4-174.461.90000112.5H705 P706 S710 H711 M712H705-S708 WeakPolarHBondContact O-CB 3.39Å; H705-S708 PolarHBondContact O-N 2.61Å; H705-S708 PolarHBondContact O-OG 3.46Å; P706-S708 PolarHBondContact O-N 2.8Å; S708-S710 PolarHBondContact O-N 3.25Å; S708-S710 VanDerWaalsContact O-N 3.11Å; S708-H711 WeakPolarHBondContact O-CA 3.41Å; S708-H711 WeakPolarHBondContact O-CB 3.47Å; S708-H711 PolarHBondContact O-N 3.39Å; S708-M712 VanDerWaalsContact O-CG 3.29Å; S708-M712 WeakPolarHBondContact O-CG 3.36Å; S708-M712 PolarHBondContact O-N 2.87Å; S708-M712 VanDerWaalsContact OG-CE 3.3Å; S708-M712 WeakPolarHBondContact OG-CE 3.43Å
709G79.7Confident85.1Confident2 Ų251.7 Ų51.72%0.02126%0.264CS..Hα-helixtrans-54.9-33.2176.600000114.3Q707 M712 R713Q707-G709 PolarHBondContact O-N 3.5Å; Q707-G709 VanDerWaalsContact O-N 3.16Å; G709-M712 PolarHBondContact O-N 3.34Å; G709-R713 VanDerWaalsContact O-CG 3.23Å; G709-R713 WeakPolarHBondContact O-CG 3.21Å; G709-R713 PolarHBondContact O-N 3.49Å
710S78.1Confident85.1Confident67 Ų6750.2 Ų50.247%0.46927%0.266SS..Hα-helixtrans-71.7-31.2177.169.50000113.3Q707 S708 K715Q707-S710 PolarHBondContact O-N 3.16Å; Q707-S710 PolarHBondContact O-OG 3.46Å; S708-S710 PolarHBondContact O-N 3.25Å; S708-S710 VanDerWaalsContact O-N 3.11Å; S710-K715 PolarHBondContact O-NZ 2.89Å
711H78.5Confident84.7Confident43 Ų4351.5 Ų51.520%0.19928%0.275CS..Hα-helixtrans-77.5-32.1174.5-67.3-87.7000111.6I244 H389 S708I244-H711 WeakPolarHBondContact CG1-O 3.48Å; H389-H711 AromaticContact CE1-ND1 3.71Å; H389-H711 AromaticContact ND1-CE1 3.6Å; H389-H711 AromaticContact ND1-ND1 3.24Å; H389-H711 PolarHBondContact ND1-ND1 2.89Å; S708-H711 WeakPolarHBondContact O-CA 3.41Å; S708-H711 WeakPolarHBondContact O-CB 3.47Å; S708-H711 PolarHBondContact O-N 3.39Å
712M77.7Confident84.5Confident3 Ų356.7 Ų56.72%0.01530%0.302CS..Hα-helixtrans-89.9-4.5-175.3-58.4-166.5-82.500114.6M504 N505 F701 S708 G709M504-M712 HydrophobicContact CE-CB 4.15Å; M504-M712 HydrophobicContact CE-CG 3.35Å; M504-M712 HydrophobicContact CE-SD 3.39Å; M504-M712 WeakPolarHBondContact CE-SD 3.33Å; N505-M712 HydrophobicContact CB-CB 3.98Å; N505-M712 WeakPolarHBondContact CB-O 3.46Å; F701-M712 HydrophobicContact CE1-CE 4.23Å; S708-M712 VanDerWaalsContact O-CG 3.29Å; S708-M712 WeakPolarHBondContact O-CG 3.36Å; S708-M712 PolarHBondContact O-N 2.87Å; S708-M712 VanDerWaalsContact OG-CE 3.3Å; S708-M712 WeakPolarHBondContact OG-CE 3.43Å; G709-M712 PolarHBondContact O-N 3.34Å
713R78.9Confident84.5Confident92 Ų9254.4 Ų54.435%0.34730%0.297SS..SBendtrans-78.7129.8178.6-86171176.9-166.8-2.7112.6S482 G709 K715 I717S482-R713 PolarHBondContact O-NH2 3Å; G709-R713 VanDerWaalsContact O-CG 3.23Å; G709-R713 WeakPolarHBondContact O-CG 3.21Å; G709-R713 PolarHBondContact O-N 3.49Å; R713-K715 PolarHBondContact O-N 3.1Å; R713-I717 HydrophobicContact CG-CD1 4.46Å
714L81.6Confident84.2Confident44 Ų4451.9 Ų51.923%0.2328%0.279CS..  trans-53.9130.6163.9-80.1178.5000110.9I244 P246 T503 I717I244-L714 HydrophobicContact CG2-CD2 4.08Å; I244-L714 HydrophobicContact CG2-CG 4.48Å; I244-L714 WeakPolarHBondContact O-CD2 3.46Å; P246-L714 HydrophobicContact CG-CD2 4.21Å; T503-L714 HydrophobicContact CG2-CD1 3.81Å; T503-L714 HydrophobicContact CG2-CD2 3.63Å; T503-L714 HydrophobicContact CG2-CG 3.76Å; L714-I717 HydrophobicContact CB-CG2 3.59Å; L714-I717 HydrophobicContact CD1-CG2 4.05Å; L714-I717 WeakPolarHBondContact O-CG1 3.49Å
715K82Confident83.9Confident60 Ų6051.6 Ų51.626%0.26128%0.278SS..G310 helixtrans-77.4-22.6-179.5-60.4-51.5-176.3-1680114Y189 P191 F388 S710 R713 I717Y189-K715 HydrophobicContact CE1-CG 4.12Å; P191-K715 HydrophobicContact CG-CB 4.01Å; F388-K715 VanDerWaalsContact CZ-CE 3.45Å; S710-K715 PolarHBondContact O-NZ 2.89Å; R713-K715 PolarHBondContact O-N 3.1Å; K715-I717 VanDerWaalsContact C-N 3.34Å; K715-I717 PolarHBondContact O-N 2.95Å
716G80.9Confident83.8Confident11 Ų1150.9 Ų50.911%0.11328%0.275CS..G310 helixtrans-70.3-21.317800000115.5T718 M719G716-T718 PolarHBondContact O-N 3.3Å; G716-T718 VanDerWaalsContact O-N 3.15Å; G716-M719 WeakPolarHBondContact O-CB 3.46Å; G716-M719 PolarHBondContact O-N 3.24Å; G716-M719 VanDerWaalsContact O-N 3.11Å
717I77.1Confident84Confident58 Ų5852.6 Ų52.630%0.29728%0.275SS..G310 helixtrans-64.9-24.6-171.369.9-173.6000113.5R713 L714 K715R713-I717 HydrophobicContact CG-CD1 4.46Å; L714-I717 HydrophobicContact CB-CG2 3.59Å; L714-I717 HydrophobicContact CD1-CG2 4.05Å; L714-I717 WeakPolarHBondContact O-CG1 3.49Å; K715-I717 VanDerWaalsContact C-N 3.34Å; K715-I717 PolarHBondContact O-N 2.95Å
718T79.7Confident84.4Confident77 Ų7752.4 Ų52.447%0.47228%0.276SS..G310 helixtrans-100.510.9-177.965.50000112.8R192 G716R192-T718 PolarHBondContact NH2-OG1 2.82Å; G716-T718 PolarHBondContact O-N 3.3Å; G716-T718 VanDerWaalsContact O-N 3.15Å
719M85.4Confident84.9Confident20 Ų2052.3 Ų52.310%0.09928%0.275CS..SBendtrans-101.2141.6-178.5-63.9174.865.400110V180 P191 R192 G716 T723V180-M719 HydrophobicContact CG1-SD 3.69Å; P191-M719 HydrophobicContact CB-SD 4.09Å; P191-M719 WeakPolarHBondContact O-CE 3.26Å; R192-M719 HydrophobicContact CG-CG 4.32Å; G716-M719 WeakPolarHBondContact O-CB 3.46Å; G716-M719 PolarHBondContact O-N 3.24Å; G716-M719 VanDerWaalsContact O-N 3.11Å; M719-T723 HydrophobicContact CE-CG2 3.47Å; M719-T723 VanDerWaalsContact CE-CG2 3.47Å
720A89Confident85.6Confident66 Ų6655.2 Ų55.255%0.54529%0.29SS..  trans-60.7149.1170.700000110.9L722 T723 Y724A720-L722 VanDerWaalsContact C-N 3.25Å; A720-L722 PolarHBondContact O-N 2.93Å; A720-L722 VanDerWaalsContact O-N 3.17Å; A720-T723 WeakPolarHBondContact O-CB 3.44Å; A720-T723 PolarHBondContact O-N 3.38Å; A720-Y724 PolarHBondContact O-N 3.2Å
721S85.9Confident86.4Confident64 Ų6453.5 Ų53.545%0.44828%0.283SS..Hα-helixtrans-54.6-38.4-175.4-130.80000113.8R725S721-R725 PolarHBondContact O-N 3.03Å; S721-R725 VanDerWaalsContact O-N 3.14Å; S721-R725 PolarHBondContact OG-NH1 3.42Å
722L88.6Confident87.2Confident111 Ų11155.3 Ų55.358%0.58129%0.29SS*.Hα-helixtrans-66.4-45.8176.9-64.2177.6000111.2A720 R725 S726 F727A720-L722 VanDerWaalsContact C-N 3.25Å; A720-L722 PolarHBondContact O-N 2.93Å; A720-L722 VanDerWaalsContact O-N 3.17Å; L722-R725 PolarHBondContact O-N 2.85Å; L722-S726 PolarHBondContact O-N 3.12Å; L722-S726 VanDerWaalsContact O-N 3.09Å; L722-F727 HydrophobicContact CD2-CB 4.25Å; L722-F727 HydrophobicContact CD2-CD2 3.93Å; L722-F727 PolarHBondContact O-N 3.09Å
723T89.3Confident88Confident32 Ų3257.1 Ų57.120%0.19630%0.299CS..Hα-helixtrans-65-43.4179.3-49.40000111.6R197 M719 A720 R725 S726R197-T723 PolarHBondContact NH1-O 3.26Å; R197-T723 VanDerWaalsContact NH1-O 3.09Å; M719-T723 HydrophobicContact CE-CG2 3.47Å; M719-T723 VanDerWaalsContact CE-CG2 3.47Å; A720-T723 WeakPolarHBondContact O-CB 3.44Å; A720-T723 PolarHBondContact O-N 3.38Å; T723-R725 VanDerWaalsContact C-N 3.35Å; T723-S726 PolarHBondContact O-N 3.13Å
724Y89.1Confident88.9Confident71 Ų7156 Ų5628%0.27831%0.305SS..Hα-helixtrans-66.8-31.5178.4177.4-103.7000113P177 S179 V180 A720 S726P177-Y724 WeakPolarHBondContact CB-O 3.26Å; P177-Y724 WeakPolarHBondContact CD-OH 2.89Å; P177-Y724 HydrophobicContact CG-CD1 4.06Å; P177-Y724 HydrophobicContact CG-CE1 3.57Å; P177-Y724 HydrophobicContact CG-CE2 4.08Å; P177-Y724 VanDerWaalsContact CG-O 3.31Å; P177-Y724 WeakPolarHBondContact CG-O 3.49Å; S179-Y724 PolarHBondContact OG-O 2.84Å; V180-Y724 HydrophobicContact CG1-CD2 3.77Å; V180-Y724 HydrophobicContact CG1-CE2 3.81Å; V180-Y724 HydrophobicContact CG2-CE2 4.07Å; A720-Y724 PolarHBondContact O-N 3.2Å; Y724-S726 VanDerWaalsContact C-N 3.35Å
725R88.1Confident89.6Confident110 Ų11059.4 Ų59.442%0.41532%0.322SS..THydrogen-bonded Turntrans-91.52.7174.2-65.8-169-172.984.3-0.2113.4S721 L722 T723 F727S721-R725 PolarHBondContact O-N 3.03Å; S721-R725 VanDerWaalsContact O-N 3.14Å; S721-R725 PolarHBondContact OG-NH1 3.42Å; L722-R725 PolarHBondContact O-N 2.85Å; T723-R725 VanDerWaalsContact C-N 3.35Å; R725-F727 HydrophobicContact CB-CD1 4.26Å; R725-F727 HydrophobicContact CB-CD2 3.95Å; R725-F727 HydrophobicContact CB-CE1 4.21Å; R725-F727 HydrophobicContact CB-CE2 3.92Å; R725-F727 HydrophobicContact CB-CG 4.12Å; R725-F727 HydrophobicContact CB-CZ 4.05Å; R725-F727 HydrophobicContact CG-CE2 4.4Å; R725-F727 PolarHBondContact O-N 2.88Å
726S91.8Very high90.3Very high3 Ų361 Ų612%0.02133%0.333CS..THydrogen-bonded Turntrans55.926.3-175.2-52.30000114.1S179 L722 T723 Y724 D728 V729 L730S179-S726 VanDerWaalsContact CB-OG 3.31Å; S179-S726 WeakPolarHBondContact CB-OG 3.45Å; L722-S726 PolarHBondContact O-N 3.12Å; L722-S726 VanDerWaalsContact O-N 3.09Å; T723-S726 PolarHBondContact O-N 3.13Å; Y724-S726 VanDerWaalsContact C-N 3.35Å; S726-D728 VanDerWaalsContact C-N 3.29Å; S726-D728 PolarHBondContact O-N 3.24Å; S726-V729 WeakPolarHBondContact O-CB 3.48Å; S726-V729 PolarHBondContact O-N 3.41Å; S726-V729 VanDerWaalsContact O-N 3.15Å; S726-L730 WeakPolarHBondContact O-CG 3.08Å; S726-L730 PolarHBondContact O-N 3.34Å
727F92.8Very high90.9Very high110 Ų11066.1 Ų66.148%0.48236%0.357SS..Hα-helixtrans-66.8-31.6-178.4-74.2-31.2000112.9L722 R725 L730 G731L722-F727 HydrophobicContact CD2-CB 4.25Å; L722-F727 HydrophobicContact CD2-CD2 3.93Å; L722-F727 PolarHBondContact O-N 3.09Å; R725-F727 HydrophobicContact CB-CD1 4.26Å; R725-F727 HydrophobicContact CB-CD2 3.95Å; R725-F727 HydrophobicContact CB-CE1 4.21Å; R725-F727 HydrophobicContact CB-CE2 3.92Å; R725-F727 HydrophobicContact CB-CG 4.12Å; R725-F727 HydrophobicContact CB-CZ 4.05Å; R725-F727 HydrophobicContact CG-CE2 4.4Å; R725-F727 PolarHBondContact O-N 2.88Å; F727-L730 HydrophobicContact CD1-CD1 4.23Å; F727-G731 PolarHBondContact O-N 3.08Å
728D93.6Very high91.9Very high55 Ų5569 Ų6929%0.29437%0.373SS..Hα-helixtrans-65.8-39.5170.856.8-23.2000112.5R197 S726 F732R197-D728 IonicContact CZ-OD1 2.86Å; R197-D728 IonicContact CZ-OD2 3.35Å; R197-D728 IonicContact NH1-OD1 3.66Å; R197-D728 PolarHBondContact NH1-OD1 2.68Å; R197-D728 IonicContact NH1-OD2 3.37Å; R197-D728 PolarHBondContact NH1-OD2 3.44Å; R197-D728 IonicContact NH2-OD1 3.45Å; R197-D728 IonicContact NH2-OD2 3.12Å; R197-D728 PolarHBondContact NH2-OD2 3.15Å; S726-D728 VanDerWaalsContact C-N 3.29Å; S726-D728 PolarHBondContact O-N 3.24Å; D728-F732 WeakPolarHBondContact O-CB 3.41Å; D728-F732 PolarHBondContact O-N 2.76Å
729V95.4Very high92.7Very high0 Ų067.6 Ų67.60%037%0.368CS..Hα-helixtrans-66.7-46.2174.1176.20000110.8F194 R197 L198 V201 S726 G731 F732 M733F194-V729 HydrophobicContact CD2-CG2 4.01Å; F194-V729 HydrophobicContact CE2-CB 4.34Å; F194-V729 HydrophobicContact CE2-CG2 3.71Å; F194-V729 HydrophobicContact CZ-CG2 4.27Å; R197-V729 HydrophobicContact CB-CG2 3.93Å; L198-V729 HydrophobicContact CB-CG1 4.15Å; L198-V729 HydrophobicContact CD1-CG1 3.72Å; V201-V729 HydrophobicContact CB-CG1 4.09Å; V201-V729 HydrophobicContact CG1-CG1 4.37Å; V201-V729 HydrophobicContact CG2-CB 4.48Å; V201-V729 HydrophobicContact CG2-CG1 3.95Å; S726-V729 WeakPolarHBondContact O-CB 3.48Å; S726-V729 PolarHBondContact O-N 3.41Å; S726-V729 VanDerWaalsContact O-N 3.15Å; V729-G731 VanDerWaalsContact C-N 3.34Å; V729-G731 PolarHBondContact O-N 3.3Å; V729-F732 WeakPolarHBondContact O-CB 3.41Å; V729-F732 PolarHBondContact O-N 2.95Å; V729-M733 HydrophobicContact CG1-SD 4.29Å; V729-M733 WeakPolarHBondContact O-CG 3.5Å; V729-M733 PolarHBondContact O-N 3.26Å
730L94Very high93.2Very high62 Ų6272.8 Ų72.833%0.32539%0.391SS..Hα-helixtrans-63.3-41.2177.2-68.9173.9000111.4V201 F205 S726 F727 M733 C734V201-L730 HydrophobicContact CG1-CD2 4.12Å; F205-L730 HydrophobicContact CE2-CD2 4.4Å; F205-L730 HydrophobicContact CZ-CD2 4.48Å; S726-L730 WeakPolarHBondContact O-CG 3.08Å; S726-L730 PolarHBondContact O-N 3.34Å; F727-L730 HydrophobicContact CD1-CD1 4.23Å; L730-M733 PolarHBondContact O-N 3.32Å; L730-C734 PolarHBondContact O-N 3.06Å; L730-C734 PolarHBondContact O-SG 2.99Å
731G95.6Very high93.5Very high31 Ų3177 Ų7732%0.3239%0.394SS..Hα-helixtrans-59.6-46.1173.300000112.1F727 V729 M733 C734 I735F727-G731 PolarHBondContact O-N 3.08Å; V729-G731 VanDerWaalsContact C-N 3.34Å; V729-G731 PolarHBondContact O-N 3.3Å; G731-M733 PolarHBondContact O-N 3.41Å; G731-C734 PolarHBondContact O-N 2.79Å; G731-I735 WeakPolarHBondContact O-CG1 3.1Å; G731-I735 PolarHBondContact O-N 3.01Å
732F96Very high94Very high81 Ų8181.7 Ų81.736%0.35540%0.403SS..Hα-helixtrans-59.5-44.4174.2174.4-102.6000112.6F194 L198 D728 V729 C734 I735 L736F194-F732 HydrophobicContact CE1-CD1 4.06Å; F194-F732 HydrophobicContact CE1-CE1 4.3Å; F194-F732 HydrophobicContact CE1-CG 4.34Å; F194-F732 HydrophobicContact CE2-CB 4.39Å; F194-F732 HydrophobicContact CZ-CB 3.77Å; F194-F732 AromaticContact CZ-CD1 3.72Å; F194-F732 HydrophobicContact CZ-CD1 3.72Å; F194-F732 HydrophobicContact CZ-CD2 4.4Å; F194-F732 HydrophobicContact CZ-CE1 4.4Å; F194-F732 AromaticContact CZ-CG 3.7Å; F194-F732 HydrophobicContact CZ-CG 3.7Å; L198-F732 HydrophobicContact CD2-CE1 4.32Å; D728-F732 WeakPolarHBondContact O-CB 3.41Å; D728-F732 PolarHBondContact O-N 2.76Å; V729-F732 WeakPolarHBondContact O-CB 3.41Å; V729-F732 PolarHBondContact O-N 2.95Å; F732-C734 PolarHBondContact O-N 2.95Å; F732-I735 PolarHBondContact O-N 3.01Å; F732-L736 HydrophobicContact CD1-CD1 4.06Å; F732-L736 HydrophobicContact CE1-CD1 3.42Å; F732-L736 VanDerWaalsContact CE1-CD1 3.42Å; F732-L736 HydrophobicContact CE1-CG 4.19Å; F732-L736 HydrophobicContact CE2-CD1 4.4Å; F732-L736 HydrophobicContact CE2-CG 4.39Å; F732-L736 HydrophobicContact CZ-CD1 3.63Å; F732-L736 HydrophobicContact CZ-CD2 4.34Å; F732-L736 HydrophobicContact CZ-CG 4.08Å; F732-L736 PolarHBondContact O-N 3.16Å
733M94.5Very high94.3Very high41 Ų4181.1 Ų81.120%0.20240%0.399CS..Hα-helixtrans-62.7-40.8175.8-70.3176.366.600112.1L198 V201 L202 F205 V729 L730 G731 L736 L737L198-M733 HydrophobicContact CD1-CG 4.09Å; L198-M733 HydrophobicContact CD1-SD 4.16Å; V201-M733 HydrophobicContact CG1-SD 3.81Å; L202-M733 HydrophobicContact CD2-CE 3.95Å; F205-M733 HydrophobicContact CD2-CE 4.35Å; F205-M733 HydrophobicContact CE2-CE 4.11Å; V729-M733 HydrophobicContact CG1-SD 4.29Å; V729-M733 WeakPolarHBondContact O-CG 3.5Å; V729-M733 PolarHBondContact O-N 3.26Å; L730-M733 PolarHBondContact O-N 3.32Å; G731-M733 PolarHBondContact O-N 3.41Å; M733-L736 PolarHBondContact O-N 3.01Å; M733-L737 WeakPolarHBondContact O-CG 3.47Å; M733-L737 PolarHBondContact O-N 3.07Å
734C96.1Very high94.5Very high70 Ų7082.8 Ų82.847%0.47341%0.406SS..Hα-helixtrans-62.8-42.1176-66.70000111.6L730 G731 F732 L736 L737 L738L730-C734 PolarHBondContact O-N 3.06Å; L730-C734 PolarHBondContact O-SG 2.99Å; G731-C734 PolarHBondContact O-N 2.79Å; F732-C734 PolarHBondContact O-N 2.95Å; C734-L736 PolarHBondContact O-N 3.09Å; C734-L737 PolarHBondContact O-N 3.4Å; C734-L738 WeakPolarHBondContact O-CB 3.33Å; C734-L738 VanDerWaalsContact O-CG 3.31Å; C734-L738 WeakPolarHBondContact O-CG 3.36Å; C734-L738 PolarHBondContact O-N 3.25Å
735I97.3Very high94.7Very high115 Ų11582.6 Ų82.659%0.5941%0.408SS*.Hα-helixtrans-61.4-43.5175.9-68164.9000110.8G731 F732 L738 A739G731-I735 WeakPolarHBondContact O-CG1 3.1Å; G731-I735 PolarHBondContact O-N 3.01Å; F732-I735 PolarHBondContact O-N 3.01Å; I735-L738 PolarHBondContact O-N 3.28Å; I735-A739 WeakPolarHBondContact O-CB 3.18Å; I735-A739 PolarHBondContact O-N 2.58Å
736L96Very high94.9Very high93 Ų9379.1 Ų79.149%0.48740%0.4SS..Hα-helixtrans-62.8-41.6176.6-72.6-179.6000112.5F732 M733 C734 A739 F740F732-L736 HydrophobicContact CD1-CD1 4.06Å; F732-L736 HydrophobicContact CE1-CD1 3.42Å; F732-L736 VanDerWaalsContact CE1-CD1 3.42Å; F732-L736 HydrophobicContact CE1-CG 4.19Å; F732-L736 HydrophobicContact CE2-CD1 4.4Å; F732-L736 HydrophobicContact CE2-CG 4.39Å; F732-L736 HydrophobicContact CZ-CD1 3.63Å; F732-L736 HydrophobicContact CZ-CD2 4.34Å; F732-L736 HydrophobicContact CZ-CG 4.08Å; F732-L736 PolarHBondContact O-N 3.16Å; M733-L736 PolarHBondContact O-N 3.01Å; C734-L736 PolarHBondContact O-N 3.09Å; L736-A739 PolarHBondContact O-N 3.19Å; L736-F740 WeakPolarHBondContact O-CB 3.46Å; L736-F740 PolarHBondContact O-N 2.9Å
737L94.5Very high94.9Very high119 Ų11981.6 Ų81.662%0.62342%0.415SS*.Hα-helixtrans-65.5-41.3177.1-71.3172.7000111.9M733 C734 F740 Y741M733-L737 WeakPolarHBondContact O-CG 3.47Å; M733-L737 PolarHBondContact O-N 3.07Å; C734-L737 PolarHBondContact O-N 3.4Å; L737-F740 PolarHBondContact O-N 2.57Å; L737-Y741 WeakPolarHBondContact O-CB 3.26Å; L737-Y741 PolarHBondContact O-N 3.45Å
738L96.8Very high94.9Very high119 Ų11981.8 Ų81.862%0.62342%0.418SS*.Hα-helixtrans-66.5-41.2175.9-70.9171.7000111.9C734 I735 Y741 Y742C734-L738 WeakPolarHBondContact O-CB 3.33Å; C734-L738 VanDerWaalsContact O-CG 3.31Å; C734-L738 WeakPolarHBondContact O-CG 3.36Å; C734-L738 PolarHBondContact O-N 3.25Å; I735-L738 PolarHBondContact O-N 3.28Å; L738-Y741 PolarHBondContact O-N 3.18Å; L738-Y742 WeakPolarHBondContact O-CB 3.23Å; L738-Y742 PolarHBondContact O-N 2.79Å
739A96.9Very high94.7Very high46 Ų4684.8 Ų84.838%0.3843%0.43SS..Hα-helixtrans-63-43.8174.800000111.4I735 L736 Y742 I743I735-A739 WeakPolarHBondContact O-CB 3.18Å; I735-A739 PolarHBondContact O-N 2.58Å; L736-A739 PolarHBondContact O-N 3.19Å; A739-Y742 PolarHBondContact O-N 3Å; A739-I743 WeakPolarHBondContact O-CD1 3.1Å; A739-I743 WeakPolarHBondContact O-CG1 3.45Å; A739-I743 PolarHBondContact O-N 3.19Å
740F95.8Very high94.4Very high130 Ų13090.1 Ų90.157%0.5746%0.455SS*.Hα-helixtrans-62.7-44.2175.8-176.4-107.5000112.1L736 L737 I743 I744L736-F740 WeakPolarHBondContact O-CB 3.46Å; L736-F740 PolarHBondContact O-N 2.9Å; L737-F740 PolarHBondContact O-N 2.57Å; F740-I743 PolarHBondContact O-N 2.9Å; F740-I744 HydrophobicContact CD1-CD1 3.75Å; F740-I744 HydrophobicContact CE1-CD1 3.27Å; F740-I744 HydrophobicContact CE1-CG1 4.34Å; F740-I744 HydrophobicContact CE2-CD1 4.29Å; F740-I744 HydrophobicContact CG-CD1 4.45Å; F740-I744 HydrophobicContact CZ-CD1 3.58Å; F740-I744 HydrophobicContact CZ-CG1 4.34Å; F740-I744 WeakPolarHBondContact O-CG1 3.26Å; F740-I744 PolarHBondContact O-N 2.87Å
741Y95.6Very high93.8Very high153 Ų15391.3 Ų91.360%0.646%0.46SS*.Hα-helixtrans-60.1-46.2174.6176.3-95.6000112L737 L738 I743 I744 H745L737-Y741 WeakPolarHBondContact O-CB 3.26Å; L737-Y741 PolarHBondContact O-N 3.45Å; L738-Y741 PolarHBondContact O-N 3.18Å; Y741-I743 VanDerWaalsContact C-N 3.34Å; Y741-I743 PolarHBondContact O-N 3.31Å; Y741-I744 PolarHBondContact O-N 2.84Å; Y741-H745 WeakPolarHBondContact O-CB 3.41Å; Y741-H745 PolarHBondContact O-N 3.38Å
742Y95.8Very high93.2Very high163 Ų16394.7 Ų94.764%0.63947%0.471SS*.Hα-helixtrans-62.2-40.4177.2-180-94.6000112.2L738 A739 H745 S746L738-Y742 WeakPolarHBondContact O-CB 3.23Å; L738-Y742 PolarHBondContact O-N 2.79Å; A739-Y742 PolarHBondContact O-N 3Å; Y742-H745 PolarHBondContact O-N 3.36Å; Y742-S746 VanDerWaalsContact O-CB 3.23Å; Y742-S746 WeakPolarHBondContact O-CB 3.3Å; Y742-S746 PolarHBondContact O-N 3.16Å
743I95.2Very high92.6Very high100 Ų10095.4 Ų95.451%0.51348%0.483SS..Hα-helixtrans-62.6-46.6175.2-69.6163.4000110.5A739 F740 Y741 H745 S746 V747A739-I743 WeakPolarHBondContact O-CD1 3.1Å; A739-I743 WeakPolarHBondContact O-CG1 3.45Å; A739-I743 PolarHBondContact O-N 3.19Å; F740-I743 PolarHBondContact O-N 2.9Å; Y741-I743 VanDerWaalsContact C-N 3.34Å; Y741-I743 PolarHBondContact O-N 3.31Å; I743-H745 VanDerWaalsContact C-N 3.34Å; I743-H745 PolarHBondContact O-N 2.96Å; I743-S746 PolarHBondContact O-N 3.25Å; I743-V747 HydrophobicContact CG2-CG2 4.32Å; I743-V747 WeakPolarHBondContact O-CB 3.41Å; I743-V747 WeakPolarHBondContact O-CG2 3.46Å; I743-V747 PolarHBondContact O-N 2.84Å
744I94.2Very high91.9Very high67 Ų67100.3 Ų100.334%0.34451%0.51SS..Hα-helixtrans-59.2-47.2176.7-70.8172.2000110.7F740 Y741 V747 Q748F740-I744 HydrophobicContact CD1-CD1 3.75Å; F740-I744 HydrophobicContact CE1-CD1 3.27Å; F740-I744 HydrophobicContact CE1-CG1 4.34Å; F740-I744 HydrophobicContact CE2-CD1 4.29Å; F740-I744 HydrophobicContact CG-CD1 4.45Å; F740-I744 HydrophobicContact CZ-CD1 3.58Å; F740-I744 HydrophobicContact CZ-CG1 4.34Å; F740-I744 WeakPolarHBondContact O-CG1 3.26Å; F740-I744 PolarHBondContact O-N 2.87Å; Y741-I744 PolarHBondContact O-N 2.84Å; I744-V747 PolarHBondContact O-N 3.42Å; I744-Q748 HydrophobicContact CG2-CG 4.47Å; I744-Q748 WeakPolarHBondContact O-CB 3.16Å; I744-Q748 WeakPolarHBondContact O-CG 3.26Å; I744-Q748 PolarHBondContact O-N 3.48Å
745H93.2Very high91Very high67 Ų67100.9 Ų100.931%0.3151%0.508SS..Hα-helixtrans-63.8-42.4179.8-168-82.2000112Y741 Y742 I743 Q748 E749Y741-H745 WeakPolarHBondContact O-CB 3.41Å; Y741-H745 PolarHBondContact O-N 3.38Å; Y742-H745 PolarHBondContact O-N 3.36Å; I743-H745 VanDerWaalsContact C-N 3.34Å; I743-H745 PolarHBondContact O-N 2.96Å; H745-Q748 PolarHBondContact O-N 3.46Å; H745-E749 IonicContact CE1-OE1 2.95Å; H745-E749 PolarHBondContact CE1-OE1 3.12Å; H745-E749 VanDerWaalsContact CE1-OE1 3.3Å; H745-E749 IonicContact CE1-OE2 2.92Å; H745-E749 PolarHBondContact CE1-OE2 3.45Å; H745-E749 VanDerWaalsContact CE1-OE2 3.31Å; H745-E749 IonicContact ND1-OE2 3.26Å; H745-E749 IonicContact NE2-OE1 3.05Å; H745-E749 PolarHBondContact O-N 2.83Å
746S92.7Very high89.8Confident36 Ų3699.7 Ų99.725%0.25251%0.507SS..Hα-helixtrans-64.4-40.9176.2179.10000111.7Y742 I743 Q748 H750Y742-S746 VanDerWaalsContact O-CB 3.23Å; Y742-S746 WeakPolarHBondContact O-CB 3.3Å; Y742-S746 PolarHBondContact O-N 3.16Å; I743-S746 PolarHBondContact O-N 3.25Å; S746-Q748 VanDerWaalsContact C-N 3.34Å; S746-Q748 PolarHBondContact O-N 3.4Å; S746-H750 VanDerWaalsContact O-CB 3.3Å; S746-H750 WeakPolarHBondContact O-CB 3.41Å; S746-H750 PolarHBondContact O-N 3.05Å
747V92Very high88.2Confident56 Ų56102.2 Ų102.234%0.33952%0.521SS..Iπ-helixtrans-61-44172.5172.20000110.5I743 I744 I751 L752I743-V747 HydrophobicContact CG2-CG2 4.32Å; I743-V747 WeakPolarHBondContact O-CB 3.41Å; I743-V747 WeakPolarHBondContact O-CG2 3.46Å; I743-V747 PolarHBondContact O-N 2.84Å; I744-V747 PolarHBondContact O-N 3.42Å; V747-I751 HydrophobicContact CG1-CB 4.4Å; V747-I751 HydrophobicContact CG2-CD1 4.03Å; V747-I751 CarbonylContact O-C 3.56Å; V747-I751 WeakPolarHBondContact O-CA 3.41Å; V747-I751 WeakPolarHBondContact O-CB 3.31Å; V747-I751 PolarHBondContact O-N 3.24Å; V747-I751 VanDerWaalsContact O-N 3.13Å; V747-L752 HydrophobicContact CG1-CD1 4.42Å; V747-L752 PolarHBondContact O-N 3.38Å
748Q91Very high86.3Confident114 Ų114105.5 Ų105.553%0.53353%0.53SS..Iπ-helixtrans-67.5-40.2-180-75.6176.4-27.600113.6I744 H745 S746 L752 P753I744-Q748 HydrophobicContact CG2-CG 4.47Å; I744-Q748 WeakPolarHBondContact O-CB 3.16Å; I744-Q748 WeakPolarHBondContact O-CG 3.26Å; I744-Q748 PolarHBondContact O-N 3.48Å; H745-Q748 PolarHBondContact O-N 3.46Å; S746-Q748 VanDerWaalsContact C-N 3.34Å; S746-Q748 PolarHBondContact O-N 3.4Å; Q748-L752 WeakPolarHBondContact O-CB 3.46Å; Q748-P753 WeakPolarHBondContact O-CD 3.3Å
749E89.4Confident84.2Confident118 Ų118105.8 Ų105.855%0.55153%0.532SS*.Iπ-helixtrans-87.1-34.8-177.1-76.6-158.9152.600114.2H745 P753H745-E749 IonicContact CE1-OE1 2.95Å; H745-E749 PolarHBondContact CE1-OE1 3.12Å; H745-E749 VanDerWaalsContact CE1-OE1 3.3Å; H745-E749 IonicContact CE1-OE2 2.92Å; H745-E749 PolarHBondContact CE1-OE2 3.45Å; H745-E749 VanDerWaalsContact CE1-OE2 3.31Å; H745-E749 IonicContact ND1-OE2 3.26Å; H745-E749 IonicContact NE2-OE1 3.05Å; H745-E749 PolarHBondContact O-N 2.83Å; E749-P753 WeakPolarHBondContact O-CD 3.34Å; E749-P753 WeakPolarHBondContact O-CG 3.41Å
750H89Confident81.7Confident112 Ų112110.6 Ų110.652%0.51955%0.551SS.*Iπ-helixtrans-109.3-31.8-169.5-6171.1000112.5S746 L754S746-H750 VanDerWaalsContact O-CB 3.3Å; S746-H750 WeakPolarHBondContact O-CB 3.41Å; S746-H750 PolarHBondContact O-N 3.05Å; H750-L754 WeakPolarHBondContact O-CD1 3.48Å; H750-L754 WeakPolarHBondContact O-CG 3.46Å
751I82.8Confident79.5Confident87 Ų87113.6 Ų113.645%0.44656%0.56SS.*Iπ-helixtrans-97.8-46.8-174.6-57.5-179.3000110.6V747 L754 L755V747-I751 HydrophobicContact CG1-CB 4.4Å; V747-I751 HydrophobicContact CG2-CD1 4.03Å; V747-I751 CarbonylContact O-C 3.56Å; V747-I751 WeakPolarHBondContact O-CA 3.41Å; V747-I751 WeakPolarHBondContact O-CB 3.31Å; V747-I751 PolarHBondContact O-N 3.24Å; V747-I751 VanDerWaalsContact O-N 3.13Å; I751-L754 PolarHBondContact O-N 2.61Å; I751-L755 PolarHBondContact O-N 3.34Å; I751-L755 VanDerWaalsContact O-N 3.09Å
752L82.8Confident77Confident102 Ų102113.2 Ų113.253%0.53457%0.568SS.*G310 helixtrans-56.9-44-178.6-128.487.1000113V747 Q748 L754 L755V747-L752 HydrophobicContact CG1-CD1 4.42Å; V747-L752 PolarHBondContact O-N 3.38Å; Q748-L752 WeakPolarHBondContact O-CB 3.46Å; L752-L754 VanDerWaalsContact C-N 3.26Å; L752-L754 PolarHBondContact O-N 3.11Å; L752-L755 HydrophobicContact CD1-CD1 4.41Å; L752-L755 WeakPolarHBondContact O-CB 3.3Å; L752-L755 PolarHBondContact O-N 3.2Å
753P82.7Confident74.6Confident95 Ų95112.3 Ų112.362%0.61758%0.579SS**G310 helixtrans-72.3-18178.4-21.736.8000114Q748 E749Q748-P753 WeakPolarHBondContact O-CD 3.3Å; E749-P753 WeakPolarHBondContact O-CD 3.34Å; E749-P753 WeakPolarHBondContact O-CG 3.41Å
754L81.1Confident71.9Confident145 Ų145121.4 Ų121.476%0.75961%0.607SS**G310 helixtrans-87.2-15.8174.4-66.9178.4000112.4H750 I751 L752H750-L754 WeakPolarHBondContact O-CD1 3.48Å; H750-L754 WeakPolarHBondContact O-CG 3.46Å; I751-L754 PolarHBondContact O-N 2.61Å; L752-L754 VanDerWaalsContact C-N 3.26Å; L752-L754 PolarHBondContact O-N 3.11Å
755L75.7Confident70.8Confident82 Ų82124.2 Ų124.243%0.42962%0.621SS.*SBendtrans-67.2126171.4-69.4169.1000107.5I751 L752 D757I751-L755 PolarHBondContact O-N 3.34Å; I751-L755 VanDerWaalsContact O-N 3.09Å; L752-L755 HydrophobicContact CD1-CD1 4.41Å; L752-L755 WeakPolarHBondContact O-CB 3.3Å; L752-L755 PolarHBondContact O-N 3.2Å; L755-D757 PolarHBondContact O-N 3.13Å
756P72.5Confident69.6Low89 Ų89127.2 Ų127.258%0.57864%0.637SS**  trans-56.5137.8-179.620.1-30.1000110.1K758 L759P756-K758 PolarHBondContact O-N 2.87Å; P756-L759 PolarHBondContact O-N 3.07Å
757D62.7Low68.3Low147 Ų147132.2 Ų132.279%0.78666%0.658SS**G310 helixtrans-50.5-10177.6-76.6-37.3000114.5L755 L759 N760L755-D757 PolarHBondContact O-N 3.13Å; D757-L759 PolarHBondContact O-N 3.13Å; D757-N760 PolarHBondContact O-N 2.9Å; D757-N760 VanDerWaalsContact O-N 3.12Å
758K54.8Low66.9Low187 Ų187136.7 Ų136.781%0.81368%0.677SS**G310 helixtrans-66.54173.5-70.2-169.2174.6-176.50115.1P756P756-K758 PolarHBondContact O-N 2.87Å
759L52.2Low65.4Low126 Ų126138.1 Ų138.166%0.6669%0.686SS**G310 helixtrans-1015.3168.5-87.5155000114.5P756 D757 Y761P756-L759 PolarHBondContact O-N 3.07Å; D757-L759 PolarHBondContact O-N 3.13Å; L759-Y761 PolarHBondContact O-N 2.75Å
760N44.3Very low63.8Low146 Ų146139.5 Ų139.578%0.78170%0.695SS**  trans-69.667.4155.4-89.7-16.6000109.6D757 D762D757-N760 PolarHBondContact O-N 2.9Å; D757-N760 VanDerWaalsContact O-N 3.12Å; N760-D762 PolarHBondContact O-N 2.6Å
761Y49.2Very low62Low194 Ų194141.4 Ų141.476%0.76171%0.708SS**  trans-74108.8151.5-91.3-86.2000106.2L759 V763L759-Y761 PolarHBondContact O-N 2.75Å; Y761-V763 VanDerWaalsContact C-N 3.34Å; Y761-V763 PolarHBondContact O-N 2.57Å
762D44.3Very low60.4Low144 Ų144145.6 Ų145.677%0.7773%0.728SS**  trans-37.597.1158.8-89.2-48.6000109.7N760 R764N760-D762 PolarHBondContact O-N 2.6Å; D762-R764 PolarHBondContact O-N 2.77Å
763V46Very low58.6Low144 Ų144149.3 Ų149.387%0.87374%0.744SS**  trans-87.381.2157.3-174.60000105.2Y761Y761-V763 VanDerWaalsContact C-N 3.34Å; Y761-V763 PolarHBondContact O-N 2.57Å
764R37.6Very low56.4Low292 Ų292154.2 Ų154.2100%1.10276%0.756SS**  trans-74.10155.9-81.4-171.1-177.2-171.61.2109.9D762D762-R764 PolarHBondContact O-N 2.77Å

Retrieved 764 of 764 residues in 166.5 ms (Link to these results)