A0A077Z504_TRITR Loading...

Arachidonate--CoA ligase

AlphaFold DB , UniProt , Accession A0A077Z504, Species TRITR (Trichuris trichiura, Whipworm), Gene n/a, Length 719 aa.

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Site Residue pLDDT pLDDT confidence pLDDT10 pLDDT10 confidence SASA SASA [Ų] SASA10 SASA10 [Ų] RSA RSA unformatted RSA10 RSA10 unformatted Surface Surface10 (not used) Disorder (not used) Disorder Sec. str. Secondary structure Isomer Phi (φ) Psi (ψ) Omega (ω) Chi 1 (χ1) Chi 2 (χ2) Chi 3 (χ3) Chi 4 (χ4) Chi 5 (χ5) Tau (τ) Contacts (colored by PAE) Contact details
1M40.1Very low40.9Very low197 Ų197104.9 Ų104.997%0.9761%0.609SS**  0-43.60-147.2-171.5-73.300111.2S4 L5M1-S4 PolarHBondContact O-OG 3.1Å; M1-L5 PolarHBondContact O-N 3.24Å
2L36.5Very low41.4Very low146 Ų146101.3 Ų101.376%0.76459%0.593SS**Hα-helixtrans-68.6-41.1171.5-79.4156.8000113.1S4 L5 A6L2-S4 VanDerWaalsContact C-N 3.35Å; L2-S4 PolarHBondContact O-N 3.03Å; L2-L5 WeakPolarHBondContact O-CB 3.48Å; L2-L5 PolarHBondContact O-N 3.42Å; L2-L5 VanDerWaalsContact O-N 3.12Å; L2-A6 PolarHBondContact O-N 3.2Å
3D42.1Very low41.8Very low129 Ų129103.2 Ų103.269%0.6959%0.591SS**Hα-helixtrans-64.6-37177.8-61.2-37.2000112.9L5 A6 D7D3-L5 PolarHBondContact O-N 3.2Å; D3-A6 PolarHBondContact O-N 3.03Å; D3-D7 PolarHBondContact O-N 3.39Å
4S45.4Very low42.6Very low74 Ų74101.5 Ų101.552%0.51759%0.585SS.*Hα-helixtrans-67.9-24.8175.763.70000113.1M1 L2 L8M1-S4 PolarHBondContact O-OG 3.1Å; L2-S4 VanDerWaalsContact C-N 3.35Å; L2-S4 PolarHBondContact O-N 3.03Å; S4-L8 WeakPolarHBondContact O-CB 3.17Å; S4-L8 PolarHBondContact O-N 3.36Å
5L32.8Very low43.7Very low99 Ų99100.9 Ų100.952%0.51858%0.584SS.*Hα-helixtrans-77.9-40.6173.1-89.6156.8000111M1 L2 D3 L8 V9M1-L5 PolarHBondContact O-N 3.24Å; L2-L5 WeakPolarHBondContact O-CB 3.48Å; L2-L5 PolarHBondContact O-N 3.42Å; L2-L5 VanDerWaalsContact O-N 3.12Å; D3-L5 PolarHBondContact O-N 3.2Å; L5-L8 PolarHBondContact O-N 3.39Å; L5-V9 VanDerWaalsContact O-CG2 3.26Å; L5-V9 WeakPolarHBondContact O-CG2 3.46Å; L5-V9 PolarHBondContact O-N 3.38Å
6A39.6Very low44.5Very low57 Ų5799.2 Ų99.247%0.47157%0.571SS.*Hα-helixtrans-62.6-43.4175.600000111.8L2 D3 L8 V9 A10L2-A6 PolarHBondContact O-N 3.2Å; D3-A6 PolarHBondContact O-N 3.03Å; A6-L8 VanDerWaalsContact C-N 3.34Å; A6-L8 PolarHBondContact O-N 2.8Å; A6-V9 PolarHBondContact O-N 3.1Å; A6-A10 VanDerWaalsContact O-CB 3.23Å; A6-A10 WeakPolarHBondContact O-CB 3.5Å; A6-A10 PolarHBondContact O-N 2.91Å
7D43.3Very low45.2Very low114 Ų11497.7 Ų97.761%0.6156%0.564SS**Hα-helixtrans-66.6-33.9175.3-76-24.3000112.5D3 S11D3-D7 PolarHBondContact O-N 3.39Å; D7-S11 WeakPolarHBondContact O-CB 3.3Å; D7-S11 PolarHBondContact O-N 3.07Å; D7-S11 PolarHBondContact O-OG 3.11Å
8L40.5Very low46.2Very low118 Ų11895 Ų9562%0.61856%0.555SS**Hα-helixtrans-69.5-38.5174.7-157.583.4000111.9S4 L5 A6 S11 S12S4-L8 WeakPolarHBondContact O-CB 3.17Å; S4-L8 PolarHBondContact O-N 3.36Å; L5-L8 PolarHBondContact O-N 3.39Å; A6-L8 VanDerWaalsContact C-N 3.34Å; A6-L8 PolarHBondContact O-N 2.8Å; L8-S11 WeakPolarHBondContact CA-OG 3.44Å; L8-S11 PolarHBondContact O-OG 3.26Å; L8-S11 VanDerWaalsContact O-OG 3.1Å; L8-S12 WeakPolarHBondContact O-CB 3.49Å; L8-S12 PolarHBondContact O-N 3.42Å; L8-S12 PolarHBondContact O-OG 3.38Å
9V40.1Very low47.3Very low87 Ų8792.1 Ų92.153%0.52754%0.539SS..Hα-helixtrans-72.5-40.8176.6174.10000110.9L5 A6 S12 F13L5-V9 VanDerWaalsContact O-CG2 3.26Å; L5-V9 WeakPolarHBondContact O-CG2 3.46Å; L5-V9 PolarHBondContact O-N 3.38Å; A6-V9 PolarHBondContact O-N 3.1Å; V9-S12 WeakPolarHBondContact CA-OG 3.18Å; V9-S12 PolarHBondContact O-N 3.04Å; V9-S12 PolarHBondContact O-OG 3.35Å; V9-F13 PolarHBondContact O-N 2.93Å; V9-F13 VanDerWaalsContact O-N 3.13Å
10A41.8Very low48.4Very low61 Ų6189.8 Ų89.850%0.50453%0.526SS..Hα-helixtrans-68.9-35.6176.900000112.4A6 P14A6-A10 VanDerWaalsContact O-CB 3.23Å; A6-A10 WeakPolarHBondContact O-CB 3.5Å; A6-A10 PolarHBondContact O-N 2.91Å; A10-P14 WeakPolarHBondContact O-CD 3.31Å
11S47.6Very low49.3Very low72 Ų7288.5 Ų88.550%0.50353%0.526SS..Hα-helixtrans-74.6-25.517656.90000113.5D7 L8D7-S11 WeakPolarHBondContact O-CB 3.3Å; D7-S11 PolarHBondContact O-N 3.07Å; D7-S11 PolarHBondContact O-OG 3.11Å; L8-S11 WeakPolarHBondContact CA-OG 3.44Å; L8-S11 PolarHBondContact O-OG 3.26Å; L8-S11 VanDerWaalsContact O-OG 3.1Å
12S47Very low50.9Low61 Ų6185.4 Ų85.443%0.42751%0.51SS..Hα-helixtrans-83.6-23.4175.647.50000113.6L8 V9 V15 L16L8-S12 WeakPolarHBondContact O-CB 3.49Å; L8-S12 PolarHBondContact O-N 3.42Å; L8-S12 PolarHBondContact O-OG 3.38Å; V9-S12 WeakPolarHBondContact CA-OG 3.18Å; V9-S12 PolarHBondContact O-N 3.04Å; V9-S12 PolarHBondContact O-OG 3.35Å; S12-V15 PolarHBondContact O-N 3.29Å; S12-L16 WeakPolarHBondContact O-CB 3.17Å; S12-L16 PolarHBondContact O-N 2.84Å
13F47.1Very low52.5Low127 Ų12778.9 Ų78.956%0.55748%0.476SS*.Hα-helixtrans-58.4-48.7179.9-139.9-91.2000113.5V9 V15 L16 T17V9-F13 PolarHBondContact O-N 2.93Å; V9-F13 VanDerWaalsContact O-N 3.13Å; F13-V15 VanDerWaalsContact C-N 3.33Å; F13-V15 PolarHBondContact O-N 3.47Å; F13-L16 WeakPolarHBondContact O-CB 3.34Å; F13-L16 PolarHBondContact O-N 3.37Å; F13-T17 HydrophobicContact CD1-CG2 4.41Å; F13-T17 HydrophobicContact CE1-CG2 4.42Å; F13-T17 PolarHBondContact O-N 2.71Å; F13-T17 PolarHBondContact O-OG1 3.35Å
14P53.2Low54Low79 Ų7976.2 Ų76.251%0.51347%0.465SS..Hα-helixtrans-59.1-42.6177-23.732.7000112.4A10 T17 A18A10-P14 WeakPolarHBondContact O-CD 3.31Å; P14-T17 VanDerWaalsContact CA-OG1 3.27Å; P14-T17 WeakPolarHBondContact CA-OG1 3.49Å; P14-T17 PolarHBondContact O-N 2.92Å; P14-T17 PolarHBondContact O-OG1 3.17Å; P14-A18 VanDerWaalsContact O-CB 3.26Å; P14-A18 WeakPolarHBondContact O-CB 3.18Å; P14-A18 PolarHBondContact O-N 3.08Å
15V57.9Low55.4Low93 Ų9374.6 Ų74.656%0.56446%0.459SS*.Hα-helixtrans-64.3-45.1178-178.70000110.1S12 F13 A18 V19S12-V15 PolarHBondContact O-N 3.29Å; F13-V15 VanDerWaalsContact C-N 3.33Å; F13-V15 PolarHBondContact O-N 3.47Å; V15-A18 PolarHBondContact O-N 3.17Å; V15-V19 HydrophobicContact CG1-CG2 4.41Å; V15-V19 VanDerWaalsContact O-CG2 3.29Å; V15-V19 WeakPolarHBondContact O-CG2 3.23Å; V15-V19 PolarHBondContact O-N 2.9Å
16L56.7Low57.2Low73 Ų7370.4 Ų70.438%0.38244%0.439SS..Hα-helixtrans-60.2-49.3176.5-174.867.3000111.1S12 F13 A18 V19 V20 L406S12-L16 WeakPolarHBondContact O-CB 3.17Å; S12-L16 PolarHBondContact O-N 2.84Å; F13-L16 WeakPolarHBondContact O-CB 3.34Å; F13-L16 PolarHBondContact O-N 3.37Å; L16-A18 VanDerWaalsContact C-N 3.34Å; L16-A18 PolarHBondContact O-N 2.95Å; L16-V19 PolarHBondContact O-N 3.13Å; L16-V20 WeakPolarHBondContact O-CB 3.47Å; L16-V20 VanDerWaalsContact O-CG2 3.25Å; L16-V20 WeakPolarHBondContact O-CG2 3.39Å; L16-V20 PolarHBondContact O-N 2.8Å; L16-L406 HydrophobicContact CD1-CB 3.83Å; L16-L406 HydrophobicContact CD1-CD1 3.63Å; L16-L406 HydrophobicContact CD1-CD2 3.67Å; L16-L406 HydrophobicContact CD1-CG 3.89Å
17T57Low58.6Low74 Ų7468.1 Ų68.145%0.45442%0.42SS..Hα-helixtrans-62.2-38.4175.833.10000112.7F13 P14 V20 A21F13-T17 HydrophobicContact CD1-CG2 4.41Å; F13-T17 HydrophobicContact CE1-CG2 4.42Å; F13-T17 PolarHBondContact O-N 2.71Å; F13-T17 PolarHBondContact O-OG1 3.35Å; P14-T17 VanDerWaalsContact CA-OG1 3.27Å; P14-T17 WeakPolarHBondContact CA-OG1 3.49Å; P14-T17 PolarHBondContact O-N 2.92Å; P14-T17 PolarHBondContact O-OG1 3.17Å; T17-V20 PolarHBondContact O-N 3.32Å; T17-A21 WeakPolarHBondContact O-CB 3.49Å; T17-A21 PolarHBondContact O-N 2.88Å
18A63.3Low59.8Low49 Ų4965.6 Ų65.641%0.40542%0.415SS..Hα-helixtrans-67.1-43.2177.800000111.4P14 V15 L16 A21 M22P14-A18 VanDerWaalsContact O-CB 3.26Å; P14-A18 WeakPolarHBondContact O-CB 3.18Å; P14-A18 PolarHBondContact O-N 3.08Å; V15-A18 PolarHBondContact O-N 3.17Å; L16-A18 VanDerWaalsContact C-N 3.34Å; L16-A18 PolarHBondContact O-N 2.95Å; A18-A21 PolarHBondContact O-N 2.83Å; A18-M22 WeakPolarHBondContact O-CB 3.46Å; A18-M22 WeakPolarHBondContact O-CG 3.47Å; A18-M22 PolarHBondContact O-N 2.95Å
19V67.6Low61.3Low39 Ų3966.2 Ų66.224%0.23641%0.413CS..Hα-helixtrans-64.4-46175.2175.90000110.2V15 L16 A21 M22 T23 L406 I410V15-V19 HydrophobicContact CG1-CG2 4.41Å; V15-V19 VanDerWaalsContact O-CG2 3.29Å; V15-V19 WeakPolarHBondContact O-CG2 3.23Å; V15-V19 PolarHBondContact O-N 2.9Å; L16-V19 PolarHBondContact O-N 3.13Å; V19-A21 PolarHBondContact O-N 3.16Å; V19-M22 HydrophobicContact CG2-CE 4.45Å; V19-M22 PolarHBondContact O-N 3.47Å; V19-T23 WeakPolarHBondContact O-CB 3.41Å; V19-T23 PolarHBondContact O-N 3.46Å; V19-T23 PolarHBondContact O-OG1 3.35Å; V19-L406 HydrophobicContact CB-CD2 4.32Å; V19-L406 HydrophobicContact CG1-CD1 4.09Å; V19-L406 HydrophobicContact CG1-CD2 3.98Å; V19-L406 HydrophobicContact CG1-CG 4.4Å; V19-I410 HydrophobicContact CG1-CD1 3.97Å
20V69.6Low62.6Low47 Ų4762.8 Ų62.829%0.28539%0.391SS..Hα-helixtrans-59.6-46.5176.2170.70000110.7L16 T17 T23 V24 L406 F409L16-V20 WeakPolarHBondContact O-CB 3.47Å; L16-V20 VanDerWaalsContact O-CG2 3.25Å; L16-V20 WeakPolarHBondContact O-CG2 3.39Å; L16-V20 PolarHBondContact O-N 2.8Å; T17-V20 PolarHBondContact O-N 3.32Å; V20-T23 PolarHBondContact O-N 3.36Å; V20-T23 VanDerWaalsContact O-N 3.17Å; V20-V24 HydrophobicContact CG1-CG2 4.32Å; V20-V24 WeakPolarHBondContact O-CB 3.47Å; V20-V24 VanDerWaalsContact O-CG2 3.3Å; V20-V24 WeakPolarHBondContact O-CG2 3.39Å; V20-V24 PolarHBondContact O-N 3.46Å; V20-L406 HydrophobicContact CG2-CD1 3.88Å; V20-F409 HydrophobicContact CG1-CE1 4.04Å; V20-F409 HydrophobicContact CG1-CZ 4.34Å; V20-F409 HydrophobicContact CG2-CD1 4.4Å; V20-F409 HydrophobicContact CG2-CE1 4.35Å
21A67.4Low63.8Low63 Ų6364.4 Ų64.452%0.52139%0.387SS..Hα-helixtrans-63.2-42.4178.100000112.5T17 A18 V19 T23 V24 G25T17-A21 WeakPolarHBondContact O-CB 3.49Å; T17-A21 PolarHBondContact O-N 2.88Å; A18-A21 PolarHBondContact O-N 2.83Å; V19-A21 PolarHBondContact O-N 3.16Å; A21-T23 VanDerWaalsContact C-N 3.31Å; A21-T23 PolarHBondContact O-N 2.84Å; A21-V24 PolarHBondContact O-N 3.45Å; A21-G25 PolarHBondContact O-N 2.84Å
22M73.1Confident64.1Low132 Ų13264.1 Ų64.165%0.6540%0.395SS*.Hα-helixtrans-63.7-37.9173.1-76-166.5-63.600111.8A18 V19 G25 A26A18-M22 WeakPolarHBondContact O-CB 3.46Å; A18-M22 WeakPolarHBondContact O-CG 3.47Å; A18-M22 PolarHBondContact O-N 2.95Å; V19-M22 HydrophobicContact CG2-CE 4.45Å; V19-M22 PolarHBondContact O-N 3.47Å; M22-G25 PolarHBondContact O-N 3.45Å; M22-A26 VanDerWaalsContact O-CB 3.25Å; M22-A26 WeakPolarHBondContact O-CB 3.01Å; M22-A26 PolarHBondContact O-N 3.26Å
23T70.3Confident64.5Low8 Ų865.9 Ų65.95%0.04940%0.399CS..Hα-helixtrans-69.6-42179.2-48.90000110.9V19 V20 A21 A26 A27 I410 L413 W433V19-T23 WeakPolarHBondContact O-CB 3.41Å; V19-T23 PolarHBondContact O-N 3.46Å; V19-T23 PolarHBondContact O-OG1 3.35Å; V20-T23 PolarHBondContact O-N 3.36Å; V20-T23 VanDerWaalsContact O-N 3.17Å; A21-T23 VanDerWaalsContact C-N 3.31Å; A21-T23 PolarHBondContact O-N 2.84Å; T23-A26 PolarHBondContact O-N 2.97Å; T23-A27 PolarHBondContact O-N 3.44Å; T23-I410 HydrophobicContact CG2-CB 4.47Å; T23-I410 HydrophobicContact CG2-CG1 3.98Å; T23-I410 HydrophobicContact CG2-CG2 4.29Å; T23-L413 HydrophobicContact CG2-CD2 3.77Å; T23-W433 HydrophobicContact CG2-CH2 3.73Å; T23-W433 HydrophobicContact CG2-CZ3 3.71Å
24V72.4Confident64.7Low74 Ų7462.3 Ų62.345%0.44840%0.398SS..Hα-helixtrans-66-41.6173.3172.60000110.7V20 A21 A26 A27 A28V20-V24 HydrophobicContact CG1-CG2 4.32Å; V20-V24 WeakPolarHBondContact O-CB 3.47Å; V20-V24 VanDerWaalsContact O-CG2 3.3Å; V20-V24 WeakPolarHBondContact O-CG2 3.39Å; V20-V24 PolarHBondContact O-N 3.46Å; A21-V24 PolarHBondContact O-N 3.45Å; V24-A26 VanDerWaalsContact C-N 3.35Å; V24-A27 WeakPolarHBondContact O-CB 3.33Å; V24-A27 PolarHBondContact O-N 2.74Å; V24-A28 WeakPolarHBondContact O-CB 3.46Å; V24-A28 PolarHBondContact O-N 2.89Å
25G75.1Confident64.6Low39 Ų3959.1 Ų59.140%0.40238%0.38SS..Hα-helixtrans-62.6-40174.200000112.4A21 M22 A28 F29A21-G25 PolarHBondContact O-N 2.84Å; M22-G25 PolarHBondContact O-N 3.45Å; G25-A28 PolarHBondContact O-N 3.5Å; G25-F29 VanDerWaalsContact O-CB 3.26Å; G25-F29 WeakPolarHBondContact O-CB 3.34Å; G25-F29 PolarHBondContact O-N 2.99Å
26A70.2Confident64.2Low12 Ų1262 Ų6210%0.09939%0.392CS..Hα-helixtrans-64.1-41.6172.800000112M22 T23 V24 F29 Y30 I432M22-A26 VanDerWaalsContact O-CB 3.25Å; M22-A26 WeakPolarHBondContact O-CB 3.01Å; M22-A26 PolarHBondContact O-N 3.26Å; T23-A26 PolarHBondContact O-N 2.97Å; V24-A26 VanDerWaalsContact C-N 3.35Å; A26-F29 PolarHBondContact O-N 3.11Å; A26-Y30 WeakPolarHBondContact O-CB 3.36Å; A26-Y30 PolarHBondContact O-N 2.81Å; A26-I432 HydrophobicContact CB-CD1 3.79Å; A26-I432 HydrophobicContact CB-CG2 4.27Å
27A69.2Low64.2Low8 Ų860.6 Ų60.67%0.06640%0.395CS..Hα-helixtrans-63.5-45.6172.900000111.6T23 V24 F29 Y30 F31 L413 W433T23-A27 PolarHBondContact O-N 3.44Å; V24-A27 WeakPolarHBondContact O-CB 3.33Å; V24-A27 PolarHBondContact O-N 2.74Å; A27-F29 VanDerWaalsContact C-N 3.33Å; A27-F29 PolarHBondContact O-N 2.87Å; A27-Y30 WeakPolarHBondContact O-CB 3.38Å; A27-Y30 PolarHBondContact O-N 3.17Å; A27-F31 WeakPolarHBondContact O-CD2 3.41Å; A27-F31 PolarHBondContact O-N 3.29Å; A27-L413 HydrophobicContact CB-CD1 4.19Å; A27-L413 HydrophobicContact CB-CD2 4.12Å; A27-L413 HydrophobicContact CB-CG 4.29Å; A27-W433 HydrophobicContact CB-CH2 4.22Å; A27-W433 HydrophobicContact CB-CZ2 3.79Å
28A69.8Low64.5Low61 Ų6158.2 Ų58.250%0.50439%0.385SS..Hα-helixtrans-61.9-40.6176.500000111.7V24 G25 G32V24-A28 WeakPolarHBondContact O-CB 3.46Å; V24-A28 PolarHBondContact O-N 2.89Å; G25-A28 PolarHBondContact O-N 3.5Å; A28-G32 WeakPolarHBondContact O-CA 3.48Å; A28-G32 PolarHBondContact O-N 3.31Å
29F71Confident65Low132 Ų13264.5 Ų64.558%0.57940%0.403SS*.Hα-helixtrans-65.2-42.2173.4-179-102.3000111.9G25 A26 A27 F31 G32 L33G25-F29 VanDerWaalsContact O-CB 3.26Å; G25-F29 WeakPolarHBondContact O-CB 3.34Å; G25-F29 PolarHBondContact O-N 2.99Å; A26-F29 PolarHBondContact O-N 3.11Å; A27-F29 VanDerWaalsContact C-N 3.33Å; A27-F29 PolarHBondContact O-N 2.87Å; F29-F31 PolarHBondContact O-N 2.6Å; F29-G32 PolarHBondContact O-N 2.89Å; F29-L33 HydrophobicContact CD1-CD1 4.01Å; F29-L33 HydrophobicContact CD2-CD1 4.37Å; F29-L33 HydrophobicContact CD2-CG 4.38Å; F29-L33 HydrophobicContact CE1-CD1 3.37Å; F29-L33 HydrophobicContact CE1-CG 4.34Å; F29-L33 HydrophobicContact CE2-CD1 3.79Å; F29-L33 HydrophobicContact CE2-CD2 4.48Å; F29-L33 HydrophobicContact CE2-CG 4.06Å; F29-L33 HydrophobicContact CG-CD1 4.48Å; F29-L33 HydrophobicContact CZ-CD1 3.27Å; F29-L33 HydrophobicContact CZ-CG 4.06Å; F29-L33 PolarHBondContact O-N 3.27Å
30Y68.1Low65.8Low15 Ų1569 Ų696%0.05942%0.42CS..Hα-helixtrans-59.8-45.1177.3-173.9-91.1000112.4A26 A27 C417 D421 R428 W433A26-Y30 WeakPolarHBondContact O-CB 3.36Å; A26-Y30 PolarHBondContact O-N 2.81Å; A27-Y30 WeakPolarHBondContact O-CB 3.38Å; A27-Y30 PolarHBondContact O-N 3.17Å; Y30-C417 HydrophobicContact CD1-CB 3.94Å; Y30-C417 HydrophobicContact CE1-CB 3.8Å; Y30-C417 WeakPolarHBondContact CE1-O 3.44Å; Y30-D421 VanDerWaalsContact OH-CG 3.26Å; Y30-D421 PolarHBondContact OH-OD2 3.13Å; Y30-R428 PolarHBondContact OH-NH2 3.21Å; Y30-R428 VanDerWaalsContact OH-NH2 3.16Å; Y30-W433 AromaticContact CD2-CD1 3.74Å; Y30-W433 AromaticContact CD2-NE1 3.56Å; Y30-W433 AromaticContact CE2-CD1 3.53Å; Y30-W433 AromaticContact CE2-NE1 3.78Å; Y30-W433 AromaticContact CG-NE1 3.66Å; Y30-W433 AromaticContact CZ-CD1 3.87Å
31F65.8Low66.6Low95 Ų9567.6 Ų67.642%0.41741%0.41SS..Hα-helixtrans-76.4-36.8175-70.9-63.8000112.6A27 F29 G34 C417 E420A27-F31 WeakPolarHBondContact O-CD2 3.41Å; A27-F31 PolarHBondContact O-N 3.29Å; F29-F31 PolarHBondContact O-N 2.6Å; F31-G34 PolarHBondContact O-N 3.17Å; F31-C417 VanDerWaalsContact CE2-SG 3.53Å; F31-C417 HydrophobicContact CZ-CB 4.3Å; F31-E420 HydrophobicContact CE1-CB 4.19Å; F31-E420 HydrophobicContact CE1-CG 4.11Å; F31-E420 HydrophobicContact CZ-CG 4.38Å
32G54.7Low67.5Low66 Ų6668.6 Ų68.668%0.6841%0.41SS*.Hα-helixtrans-70.1-29.8-176.800000114.3A28 F29 G34A28-G32 WeakPolarHBondContact O-CA 3.48Å; A28-G32 PolarHBondContact O-N 3.31Å; F29-G32 PolarHBondContact O-N 2.89Å; G32-G34 PolarHBondContact O-N 3.12Å; G32-G34 VanDerWaalsContact O-N 3.15Å
33L55Low68.2Low98 Ų9863.3 Ų63.351%0.51339%0.385SS..THydrogen-bonded Turntrans-7410.3168.3-75.3-179.8000113.6F29 G35 N36F29-L33 HydrophobicContact CD1-CD1 4.01Å; F29-L33 HydrophobicContact CD2-CD1 4.37Å; F29-L33 HydrophobicContact CD2-CG 4.38Å; F29-L33 HydrophobicContact CE1-CD1 3.37Å; F29-L33 HydrophobicContact CE1-CG 4.34Å; F29-L33 HydrophobicContact CE2-CD1 3.79Å; F29-L33 HydrophobicContact CE2-CD2 4.48Å; F29-L33 HydrophobicContact CE2-CG 4.06Å; F29-L33 HydrophobicContact CG-CD1 4.48Å; F29-L33 HydrophobicContact CZ-CD1 3.27Å; F29-L33 HydrophobicContact CZ-CG 4.06Å; F29-L33 PolarHBondContact O-N 3.27Å; L33-G35 PolarHBondContact O-N 3.3Å; L33-G35 VanDerWaalsContact O-N 3.13Å; L33-N36 WeakPolarHBondContact O-CB 3.32Å; L33-N36 PolarHBondContact O-N 3.06Å
34G50.7Low69Low52 Ų5265.3 Ų65.354%0.53639%0.392SS..THydrogen-bonded Turntrans62.622.8174.600000114F31 G32 N36F31-G34 PolarHBondContact O-N 3.17Å; G32-G34 PolarHBondContact O-N 3.12Å; G32-G34 VanDerWaalsContact O-N 3.15Å; G34-N36 PolarHBondContact O-N 3.28Å
35G51.6Low69.9Low12 Ų1262.2 Ų62.212%0.12437%0.374CS..THydrogen-bonded Turntrans59.614.8-176.900000114.7L33 G37L33-G35 PolarHBondContact O-N 3.3Å; L33-G35 VanDerWaalsContact O-N 3.13Å; G35-G37 PolarHBondContact O-N 2.72Å
36N49.5Very low70.3Confident153 Ų15366.4 Ų66.482%0.81840%0.397SS*.THydrogen-bonded Turntrans-618.3-169.2-89.5-15.3000116.6L33 G34L33-N36 WeakPolarHBondContact O-CB 3.32Å; L33-N36 PolarHBondContact O-N 3.06Å; G34-N36 PolarHBondContact O-N 3.28Å
37G56.9Low71.2Confident44 Ų4469.2 Ų69.245%0.45441%0.41SS..THydrogen-bonded Turntrans-104.34.1-173.300000116.1G35G35-G37 PolarHBondContact O-N 2.72Å
38G64Low72.2Confident23 Ų2370.3 Ų70.324%0.23742%0.415CS..  trans-127.5135.2-17400000113.4
39K73.8Confident73.1Confident181 Ų18171.5 Ų71.579%0.78741%0.412SS*.PPolyproline II helixtrans-78.5126.6172.3-170-179.6177.5-172.60108.3
40K83.9Confident74.2Confident135 Ų13570.9 Ų70.959%0.58741%0.411SS*.BIsolated β-bridgetrans-61.1135.1171-171.5178.5-179-173.50108.9T42 A425K40-T42 PolarHBondContact O-N 3.2Å; K40-A425 WeakPolarHBondContact CA-O 3.4Å; K40-A425 HydrophobicContact CG-CB 4.02Å
41I87Confident75.5Confident16 Ų1670.1 Ų70.18%0.08241%0.408CS..PPolyproline II helixtrans-62.2127.7173.4-67.2171.9000108.5T43 A327 A425 L427 V474 E493I41-T43 HydrophobicContact CG2-CG2 4.4Å; I41-A327 HydrophobicContact CG2-CB 3.75Å; I41-A425 HydrophobicContact CB-CB 4.42Å; I41-A425 WeakPolarHBondContact CG1-O 3.21Å; I41-A425 PolarHBondContact N-O 2.78Å; I41-L427 HydrophobicContact CD1-CB 4.49Å; I41-L427 HydrophobicContact CD1-CD1 3.61Å; I41-L427 HydrophobicContact CD1-CG 3.75Å; I41-V474 HydrophobicContact CD1-CG2 4.17Å; I41-E493 HydrophobicContact CG2-CB 3.7Å
42T85.1Confident76.9Confident84 Ų8466.1 Ų66.152%0.51539%0.392SS..PPolyproline II helixtrans-88128.5171-54.70000108.1K40 A327K40-T42 PolarHBondContact O-N 3.2Å; T42-A327 WeakPolarHBondContact O-CB 3.43Å
43T87.8Confident78.8Confident22 Ų2264.9 Ų64.914%0.13537%0.369CS..  trans-110.2165.3176.4950000109.4I41 V45 L48 E493I41-T43 HydrophobicContact CG2-CG2 4.4Å; T43-V45 PolarHBondContact O-N 3.33Å; T43-V45 PolarHBondContact OG1-N 3.19Å; T43-V45 PolarHBondContact OG1-O 2.81Å; T43-L48 HydrophobicContact CG2-CD2 4.16Å; T43-E493 WeakPolarHBondContact CG2-O 3.44Å
44Y88.4Confident80.7Confident50 Ų5064.4 Ų64.420%0.19637%0.367CS..SBendtrans-71.4-15.1173.667.6-96.7000112.7S64 W65 L66 A324 L492Y44-S64 PolarHBondContact OH-OG 2.93Å; Y44-W65 HydrophobicContact CD2-CB 4.01Å; Y44-W65 HydrophobicContact CE2-CB 3.91Å; Y44-L66 HydrophobicContact CD1-CD1 4.01Å; Y44-L66 HydrophobicContact CD1-CD2 4.35Å; Y44-L66 HydrophobicContact CD1-CG 4.23Å; Y44-L66 HydrophobicContact CD2-CD1 4.13Å; Y44-L66 HydrophobicContact CD2-CD2 3.95Å; Y44-L66 HydrophobicContact CD2-CG 3.56Å; Y44-L66 HydrophobicContact CE1-CD1 3.77Å; Y44-L66 HydrophobicContact CE1-CG 4.28Å; Y44-L66 HydrophobicContact CE2-CD1 3.88Å; Y44-L66 HydrophobicContact CE2-CD2 4.48Å; Y44-L66 HydrophobicContact CE2-CG 3.61Å; Y44-L66 HydrophobicContact CG-CD1 4.17Å; Y44-L66 HydrophobicContact CG-CD2 3.84Å; Y44-L66 HydrophobicContact CG-CG 3.85Å; Y44-A324 HydrophobicContact CE1-CB 3.84Å; Y44-L492 HydrophobicContact CD1-CD2 4.49Å; Y44-L492 HydrophobicContact CE1-CD2 3.41Å; Y44-L492 VanDerWaalsContact CE1-CD2 3.41Å; Y44-L492 HydrophobicContact CE2-CD2 4.46Å; Y44-L492 VanDerWaalsContact CZ-CD2 3.41Å; Y44-L492 WeakPolarHBondContact OH-CD2 3.37Å
45V89.6Confident82.8Confident9 Ų965.7 Ų65.76%0.05536%0.359CS..SBendtrans-94.8136.5172.6-169.70000109.5T43 D47 E50 W65 L492T43-V45 PolarHBondContact O-N 3.33Å; T43-V45 PolarHBondContact OG1-N 3.19Å; T43-V45 PolarHBondContact OG1-O 2.81Å; V45-D47 WeakPolarHBondContact CG1-O 2.99Å; V45-E50 VanDerWaalsContact CG1-O 3.3Å; V45-E50 WeakPolarHBondContact CG1-O 3.32Å; V45-W65 HydrophobicContact CG1-CG 4.41Å; V45-W65 HydrophobicContact CG2-CB 4.1Å; V45-W65 HydrophobicContact CG2-CG 4.19Å; V45-L492 HydrophobicContact CB-CD1 4.06Å; V45-L492 HydrophobicContact CG2-CD1 3.5Å
46S84.4Confident84.7Confident127 Ų12766.4 Ų66.489%0.88836%0.362SS*.SBendtrans-72.2-36.317746.20000112.7
47D89.2Confident86.6Confident70 Ų7067.3 Ų67.337%0.37436%0.361SS..  trans-124.6120.7179.5-162.7-17.5000111.7V45 D49 E50V45-D47 WeakPolarHBondContact CG1-O 2.99Å; D47-D49 PolarHBondContact O-N 3.06Å; D47-D49 PolarHBondContact OD1-N 2.03Å; D47-E50 HydrophobicContact CB-CB 4.44Å; D47-E50 CarbonylContact O-C 3.39Å; D47-E50 PolarHBondContact O-N 3.2Å
48L89.4Confident88.1Confident32 Ų3274.6 Ų74.617%0.16838%0.38CS..THydrogen-bonded Turntrans-72.2-9.3177.7-74.3175.9000112.8T43 Q51 L492 D495 R568T43-L48 HydrophobicContact CG2-CD2 4.16Å; L48-Q51 VanDerWaalsContact O-CG 3.23Å; L48-Q51 WeakPolarHBondContact O-CG 3.45Å; L48-Q51 PolarHBondContact O-NE2 2.91Å; L48-L492 HydrophobicContact CD2-CB 4.27Å; L48-L492 HydrophobicContact CD2-CD1 3.98Å; L48-D495 HydrophobicContact CD2-CB 4.47Å; L48-R568 VanDerWaalsContact O-CZ 3.26Å; L48-R568 PolarHBondContact O-NE 3.15Å; L48-R568 PolarHBondContact O-NH2 3.39Å
49D90.2Very high89.3Confident85 Ų8576.3 Ų76.346%0.45538%0.382SS..THydrogen-bonded Turntrans-90.21170.2-66.1-46.8000112.8D47 R568D47-D49 PolarHBondContact O-N 3.06Å; D47-D49 PolarHBondContact OD1-N 2.03Å; D49-R568 HydrophobicContact CB-CG 4.49Å; D49-R568 VanDerWaalsContact O-CA 3.26Å; D49-R568 WeakPolarHBondContact O-CA 3.15Å; D49-R568 IonicContact OD1-CZ 2.76Å; D49-R568 VanDerWaalsContact OD1-CZ 3.24Å; D49-R568 IonicContact OD1-NE 3.43Å; D49-R568 PolarHBondContact OD1-NE 3.49Å; D49-R568 IonicContact OD1-NH1 2.86Å; D49-R568 PolarHBondContact OD1-NH1 3.17Å
50E92.6Very high90.2Very high119 Ų11971.7 Ų71.756%0.55636%0.36SS*.  trans-137.671.6174.1-66.4-174.1-172.900110.7V45 D47 W65V45-E50 VanDerWaalsContact CG1-O 3.3Å; V45-E50 WeakPolarHBondContact CG1-O 3.32Å; D47-E50 HydrophobicContact CB-CB 4.44Å; D47-E50 CarbonylContact O-C 3.39Å; D47-E50 PolarHBondContact O-N 3.2Å; E50-W65 PolarHBondContact O-NE1 3.41Å
51Q95.1Very high90.8Very high0 Ų065.3 Ų65.30%033%0.332CS..  trans-85.8-7.9-167.5-58.7-170.120.700115.8L48 W65 L492 D495 P503 R568 T570L48-Q51 VanDerWaalsContact O-CG 3.23Å; L48-Q51 WeakPolarHBondContact O-CG 3.45Å; L48-Q51 PolarHBondContact O-NE2 2.91Å; Q51-W65 VanDerWaalsContact C-CD1 3.45Å; Q51-L492 HydrophobicContact CB-CD1 3.99Å; Q51-L492 HydrophobicContact CG-CD1 3.78Å; Q51-D495 PolarHBondContact NE2-OD2 3.07Å; Q51-D495 PolarHBondContact OE1-OD2 3.42Å; Q51-P503 HydrophobicContact CB-CB 4.19Å; Q51-P503 HydrophobicContact CB-CG 4.08Å; Q51-P503 WeakPolarHBondContact O-CB 3.3Å; Q51-P503 WeakPolarHBondContact O-CG 3.05Å; Q51-R568 WeakPolarHBondContact CB-O 3.48Å; Q51-R568 PolarHBondContact N-O 2.8Å; Q51-T570 HydrophobicContact CB-CG2 3.9Å; Q51-T570 HydrophobicContact CG-CG2 3.96Å
52S96.2Very high91.3Very high10 Ų1066.8 Ų66.87%0.0734%0.336CS..EExtended strand (participates in β ladder)trans-145.5158.2177.661.20000112.3R62 I63 G569S52-R62 WeakPolarHBondContact OG-CD 3.42Å; S52-R62 PolarHBondContact OG-NH1 3.04Å; S52-I63 WeakPolarHBondContact CB-O 3.45Å; S52-G569 WeakPolarHBondContact CB-O 3.31Å; S52-G569 WeakPolarHBondContact OG-CA 3.1Å; S52-G569 PolarHBondContact OG-O 3.46Å
53I95.1Very high91.9Very high41 Ų4162.9 Ų62.921%0.2131%0.312CS..EExtended strand (participates in β ladder)trans-100.5140.5179.7-51.2170.2000109.1H55 R62 I63 W65 D68I53-H55 PolarHBondContact O-N 2.94Å; I53-R62 CarbonylContact O-C 3.5Å; I53-R62 WeakPolarHBondContact O-CA 3.4Å; I53-I63 HydrophobicContact CB-CG2 3.86Å; I53-I63 PolarHBondContact N-O 3.44Å; I53-I63 PolarHBondContact O-N 3.41Å; I53-W65 HydrophobicContact CD1-CD2 3.68Å; I53-W65 HydrophobicContact CD1-CE3 3.38Å; I53-W65 HydrophobicContact CD1-CG 4.26Å; I53-W65 HydrophobicContact CD1-CH2 4.29Å; I53-W65 HydrophobicContact CD1-CZ3 3.7Å; I53-W65 HydrophobicContact CG1-CD2 3.43Å; I53-W65 VanDerWaalsContact CG1-CD2 3.43Å; I53-W65 HydrophobicContact CG1-CE3 3.61Å; I53-W65 HydrophobicContact CG1-CG 3.98Å; I53-W65 HydrophobicContact CG1-CH2 3.94Å; I53-W65 HydrophobicContact CG1-CZ2 3.81Å; I53-W65 HydrophobicContact CG1-CZ3 3.84Å; I53-D68 HydrophobicContact CD1-CB 4.22Å
54L94.4Very high92.3Very high87 Ų8761.8 Ų61.846%0.45531%0.306SS..EExtended strand (participates in β ladder)trans-72.3109.3165.9-17467.9000109.2E57L54-E57 HydrophobicContact CD2-CG 3.97Å
55H95Very high92.7Very high80 Ų8063.6 Ų63.637%0.3731%0.312SS..EExtended strand (participates in β ladder)trans-80.3-36.2-177.5169.8-98.5000112.7I53 S61 I63 L509I53-H55 PolarHBondContact O-N 2.94Å; H55-S61 WeakPolarHBondContact CB-O 3.48Å; H55-S61 PolarHBondContact N-O 3.1Å; H55-S61 PolarHBondContact ND1-OG 3.28Å; H55-I63 HydrophobicContact CB-CB 4Å; H55-I63 HydrophobicContact CB-CG2 3.86Å; H55-L509 HydrophobicContact CB-CD2 4.07Å
56S92Very high92.9Very high27 Ų2764.7 Ų64.719%0.18932%0.318CS..EExtended strand (participates in β ladder)trans-142.9118.8-179.9172.90000109.5K58 E59 R60 S61S56-K58 VanDerWaalsContact C-N 3.28Å; S56-K58 PolarHBondContact O-N 3.32Å; S56-E59 PolarHBondContact OG-N 2.95Å; S56-R60 VanDerWaalsContact O-CA 3.25Å; S56-R60 WeakPolarHBondContact O-CA 3.49Å; S56-R60 PolarHBondContact O-N 3.21Å; S56-S61 WeakPolarHBondContact CB-OG 3.09Å; S56-S61 PolarHBondContact N-O 3.48Å; S56-S61 PolarHBondContact N-OG 3.12Å; S56-S61 PolarHBondContact O-N 3.1Å
57E89Confident93.5Very high171 Ų17158.7 Ų58.780%0.79928%0.276SS*.THydrogen-bonded Turntrans-61.9-39.2174.2-69.3-168.8169.800111.4L54 R60L54-E57 HydrophobicContact CD2-CG 3.97Å; E57-R60 PolarHBondContact O-N 3.4Å
58K89.1Confident93.5Very high198 Ų19861.3 Ų61.386%0.86129%0.29SS*.THydrogen-bonded Turntrans-65.9-45.2-178.1-177-173174.2-167.20112S56S56-K58 VanDerWaalsContact C-N 3.28Å; S56-K58 PolarHBondContact O-N 3.32Å
59E88.9Confident93.7Very high59 Ų5965.4 Ų65.428%0.27631%0.312SS..THydrogen-bonded Turntrans-89.4-8.8-178.6-65.2-171.2118.600112.9S56 S61 W556S56-E59 PolarHBondContact OG-N 2.95Å; E59-S61 PolarHBondContact O-N 3.16Å; E59-S61 VanDerWaalsContact O-N 3.12Å; E59-W556 PolarHBondContact OE1-NE1 2.76Å
60R93.1Very high93.8Very high84 Ų8462.6 Ų62.632%0.31730%0.303SS..THydrogen-bonded Turntrans50.331.1-169.6-58.8177.267.4137.4-9.5112.8S56 E57 A522 E523 D525S56-R60 VanDerWaalsContact O-CA 3.25Å; S56-R60 WeakPolarHBondContact O-CA 3.49Å; S56-R60 PolarHBondContact O-N 3.21Å; E57-R60 PolarHBondContact O-N 3.4Å; R60-A522 PolarHBondContact NE-O 3.11Å; R60-A522 VanDerWaalsContact NE-O 3.16Å; R60-A522 PolarHBondContact NH2-O 2.84Å; R60-E523 VanDerWaalsContact NH1-CA 3.28Å; R60-E523 PolarHBondContact NH1-O 3.48Å; R60-E523 PolarHBondContact NH2-O 3.21Å; R60-D525 IonicContact CZ-OD1 2.74Å; R60-D525 IonicContact NE-OD1 2.89Å; R60-D525 IonicContact NH2-OD1 3.75Å; R60-D525 PolarHBondContact NH2-OD1 3.06Å; R60-D525 IonicContact NH2-OD2 3.84Å
61S95.5Very high93.9Very high0 Ų063.6 Ų63.60%031%0.308CS..EExtended strand (participates in β ladder)trans-80.2140.9-179.465.60000110.4H55 S56 E59 I510H55-S61 WeakPolarHBondContact CB-O 3.48Å; H55-S61 PolarHBondContact N-O 3.1Å; H55-S61 PolarHBondContact ND1-OG 3.28Å; S56-S61 WeakPolarHBondContact CB-OG 3.09Å; S56-S61 PolarHBondContact N-O 3.48Å; S56-S61 PolarHBondContact N-OG 3.12Å; S56-S61 PolarHBondContact O-N 3.1Å; E59-S61 PolarHBondContact O-N 3.16Å; E59-S61 VanDerWaalsContact O-N 3.12Å; S61-I510 CarbonylContact C-O 3.45Å; S61-I510 WeakPolarHBondContact CA-O 3.35Å
62R97.4Very high94Very high47 Ų4765.2 Ų65.218%0.17732%0.316CS..EExtended strand (participates in β ladder)trans-109.9151.6174.8-67.6-179.3174-99.41.8111.9S52 I53 P504 I510 W565S52-R62 WeakPolarHBondContact OG-CD 3.42Å; S52-R62 PolarHBondContact OG-NH1 3.04Å; I53-R62 CarbonylContact O-C 3.5Å; I53-R62 WeakPolarHBondContact O-CA 3.4Å; R62-P504 HydrophobicContact CB-CG 4.24Å; R62-I510 PolarHBondContact N-O 3.49Å; R62-I510 PolarHBondContact O-N 3.28Å; R62-I510 VanDerWaalsContact O-N 3.12Å; R62-W565 HydrophobicContact CB-CH2 3.92Å; R62-W565 HydrophobicContact CB-CZ2 3.9Å; R62-W565 VanDerWaalsContact CD-CD2 3.46Å; R62-W565 VanDerWaalsContact CD-CE2 3.48Å; R62-W565 HydrophobicContact CG-CH2 4.32Å; R62-W565 HydrophobicContact CG-CZ2 4Å
63I97.5Very high94.1Very high2 Ų267.7 Ų67.71%0.0133%0.326CS..EExtended strand (participates in β ladder)trans-131.8158.7178.3-163.2174.3000110.4S52 I53 H55 C67 L72 L509S52-I63 WeakPolarHBondContact CB-O 3.45Å; I53-I63 HydrophobicContact CB-CG2 3.86Å; I53-I63 PolarHBondContact N-O 3.44Å; I53-I63 PolarHBondContact O-N 3.41Å; H55-I63 HydrophobicContact CB-CB 4Å; H55-I63 HydrophobicContact CB-CG2 3.86Å; I63-C67 HydrophobicContact CD1-CB 3.45Å; I63-C67 VanDerWaalsContact CD1-CB 3.45Å; I63-C67 HydrophobicContact CG1-CB 3.76Å; I63-L72 HydrophobicContact CD1-CD2 3.81Å; I63-L72 HydrophobicContact CG1-CD2 3.93Å; I63-L509 HydrophobicContact CB-CD2 3.66Å; I63-L509 HydrophobicContact CD1-CD2 3.85Å; I63-L509 HydrophobicContact CG1-CD2 3.75Å
64S96.7Very high94.2Very high0 Ų070.1 Ų70.10%034%0.339CS..EExtended strand (participates in β ladder)trans-67.2146.6174.4-170.60000112.3Y44 L66 C67 P504Y44-S64 PolarHBondContact OH-OG 2.93Å; S64-L66 PolarHBondContact O-N 3.3Å; S64-L66 VanDerWaalsContact O-N 3.15Å; S64-L66 PolarHBondContact OG-N 3.31Å; S64-C67 WeakPolarHBondContact O-CB 3.38Å; S64-C67 PolarHBondContact O-N 3.46Å; S64-P504 VanDerWaalsContact CB-O 3.31Å; S64-P504 WeakPolarHBondContact CB-O 3.28Å
65W96Very high94.4Very high87 Ų8768.8 Ų68.833%0.3333%0.329SS..G310 helixtrans-62.1-14.1166.7-79.2106.4000114.3Y44 V45 E50 Q51 I53 C67Y44-W65 HydrophobicContact CD2-CB 4.01Å; Y44-W65 HydrophobicContact CE2-CB 3.91Å; V45-W65 HydrophobicContact CG1-CG 4.41Å; V45-W65 HydrophobicContact CG2-CB 4.1Å; V45-W65 HydrophobicContact CG2-CG 4.19Å; E50-W65 PolarHBondContact O-NE1 3.41Å; Q51-W65 VanDerWaalsContact C-CD1 3.45Å; I53-W65 HydrophobicContact CD1-CD2 3.68Å; I53-W65 HydrophobicContact CD1-CE3 3.38Å; I53-W65 HydrophobicContact CD1-CG 4.26Å; I53-W65 HydrophobicContact CD1-CH2 4.29Å; I53-W65 HydrophobicContact CD1-CZ3 3.7Å; I53-W65 HydrophobicContact CG1-CD2 3.43Å; I53-W65 VanDerWaalsContact CG1-CD2 3.43Å; I53-W65 HydrophobicContact CG1-CE3 3.61Å; I53-W65 HydrophobicContact CG1-CG 3.98Å; I53-W65 HydrophobicContact CG1-CH2 3.94Å; I53-W65 HydrophobicContact CG1-CZ2 3.81Å; I53-W65 HydrophobicContact CG1-CZ3 3.84Å; W65-C67 PolarHBondContact O-N 3.12Å
66L94.8Very high94.4Very high33 Ų3367 Ų6717%0.17332%0.322CS..G310 helixtrans-71.1-6.7171-72.4162.9000113.1Y44 S64 K73 A324 P506Y44-L66 HydrophobicContact CD1-CD1 4.01Å; Y44-L66 HydrophobicContact CD1-CD2 4.35Å; Y44-L66 HydrophobicContact CD1-CG 4.23Å; Y44-L66 HydrophobicContact CD2-CD1 4.13Å; Y44-L66 HydrophobicContact CD2-CD2 3.95Å; Y44-L66 HydrophobicContact CD2-CG 3.56Å; Y44-L66 HydrophobicContact CE1-CD1 3.77Å; Y44-L66 HydrophobicContact CE1-CG 4.28Å; Y44-L66 HydrophobicContact CE2-CD1 3.88Å; Y44-L66 HydrophobicContact CE2-CD2 4.48Å; Y44-L66 HydrophobicContact CE2-CG 3.61Å; Y44-L66 HydrophobicContact CG-CD1 4.17Å; Y44-L66 HydrophobicContact CG-CD2 3.84Å; Y44-L66 HydrophobicContact CG-CG 3.85Å; S64-L66 PolarHBondContact O-N 3.3Å; S64-L66 VanDerWaalsContact O-N 3.15Å; S64-L66 PolarHBondContact OG-N 3.31Å; L66-K73 WeakPolarHBondContact O-CE 3.46Å; L66-K73 PolarHBondContact O-NZ 3.01Å; L66-A324 HydrophobicContact CD1-CB 4.43Å; L66-P506 HydrophobicContact CB-CB 4.27Å; L66-P506 HydrophobicContact CB-CG 3.94Å; L66-P506 HydrophobicContact CD1-CG 3.53Å; L66-P506 HydrophobicContact CG-CG 4.38Å
67C95.7Very high94.6Very high1 Ų168.1 Ų68.11%0.00732%0.323CS..G310 helixtrans-127.749.4-179.2-62.60000109.6I63 S64 W65 D69 G70 E71 P506I63-C67 HydrophobicContact CD1-CB 3.45Å; I63-C67 VanDerWaalsContact CD1-CB 3.45Å; I63-C67 HydrophobicContact CG1-CB 3.76Å; S64-C67 WeakPolarHBondContact O-CB 3.38Å; S64-C67 PolarHBondContact O-N 3.46Å; W65-C67 PolarHBondContact O-N 3.12Å; C67-D69 PolarHBondContact O-N 2.82Å; C67-G70 PolarHBondContact O-N 3.46Å; C67-E71 VanDerWaalsContact CB-O 3.23Å; C67-E71 WeakPolarHBondContact CB-O 3.4Å; C67-E71 PolarHBondContact SG-O 3.16Å; C67-P506 PolarHBondContact SG-O 3.07Å; C67-P506 VanDerWaalsContact SG-O 3.34Å
68D90Very high94.9Very high125 Ų12565 Ų6567%0.66832%0.318SS*.THydrogen-bonded Turntrans-68.6-15.6-177.263.4-22.3000113.8I53I53-D68 HydrophobicContact CD1-CB 4.22Å
69D92.9Very high95.2Very high118 Ų11858.9 Ų58.963%0.63129%0.294SS*.THydrogen-bonded Turntrans-77.6-6.4167.661.8-1.1000113.8C67 E71C67-D69 PolarHBondContact O-N 2.82Å; D69-E71 VanDerWaalsContact C-N 3.34Å; D69-E71 PolarHBondContact OD1-N 2.91Å
70G92.5Very high95.6Very high26 Ų2656.1 Ų56.127%0.26828%0.281SS..SBendtrans850.3-177.100000114.4C67C67-G70 PolarHBondContact O-N 3.46Å
71E95.8Very high95.9Very high139 Ų13956.8 Ų56.865%0.6528%0.284SS*.PPolyproline II helixtrans-102.6130.9-176.3-65.8-67.1155.200111.5C67 D69C67-E71 VanDerWaalsContact CB-O 3.23Å; C67-E71 WeakPolarHBondContact CB-O 3.4Å; C67-E71 PolarHBondContact SG-O 3.16Å; D69-E71 VanDerWaalsContact C-N 3.34Å; D69-E71 PolarHBondContact OD1-N 2.91Å
72L97.7Very high96Very high35 Ų3556.9 Ų56.918%0.18328%0.284CS..PPolyproline II helixtrans-70.4143.8178.7-65.3174.3000111.4I63 L74 P506 L509I63-L72 HydrophobicContact CD1-CD2 3.81Å; I63-L72 HydrophobicContact CG1-CD2 3.93Å; L72-L74 PolarHBondContact O-N 3.03Å; L72-P506 WeakPolarHBondContact CD2-O 3.37Å; L72-L509 HydrophobicContact CD1-CG 4.12Å; L72-L509 HydrophobicContact CD2-CD2 4.18Å; L72-L509 HydrophobicContact CD2-CG 4.13Å; L72-L509 HydrophobicContact CG-CG 4.42Å
73K97.2Very high96Very high62 Ų6254.7 Ų54.727%0.2728%0.276SS..PPolyproline II helixtrans-75.4124.7176-63.8-167.3-176.2178.20110.9L66 T320 S323 P506L66-K73 WeakPolarHBondContact O-CE 3.46Å; L66-K73 PolarHBondContact O-NZ 3.01Å; K73-T320 HydrophobicContact CB-CG2 3.68Å; K73-S323 PolarHBondContact NZ-OG 3.32Å; K73-P506 HydrophobicContact CB-CB 3.98Å; K73-P506 HydrophobicContact CD-CB 3.81Å; K73-P506 HydrophobicContact CG-CB 3.87Å; K73-P506 PolarHBondContact N-O 2.92Å
74L97.5Very high96Very high91 Ų9155.7 Ų55.748%0.47628%0.28SS..  trans-91.6-28.5179.1-54.8-175.4000113.4L72 A317 P534L72-L74 PolarHBondContact O-N 3.03Å; L74-A317 VanDerWaalsContact O-CA 3.24Å; L74-A317 WeakPolarHBondContact O-CA 3.32Å; L74-A317 WeakPolarHBondContact O-CB 3.33Å; L74-A317 PolarHBondContact O-N 3.03Å; L74-P534 HydrophobicContact CD2-CB 3.8Å; L74-P534 HydrophobicContact CD2-CG 3.77Å
75F97.5Very high96.1Very high60 Ų6057.8 Ų57.826%0.26329%0.291SS..  trans-165.2159.1-178.551-92000110Y77 P78 V316F75-Y77 VanDerWaalsContact CD2-C 3.5Å; F75-Y77 WeakPolarHBondContact CD2-O 3.28Å; F75-P78 HydrophobicContact CE2-CB 4.27Å; F75-P78 HydrophobicContact CE2-CG 4.14Å; F75-V316 HydrophobicContact CB-CG1 3.68Å
76L95.4Very high96.2Very high42 Ų4253.6 Ų53.622%0.2228%0.275CS..SBendtrans-87-31.5174.3-69.3174.3000113.2G319 T320 E322L76-G319 WeakPolarHBondContact CD1-O 3.46Å; L76-T320 HydrophobicContact CD2-CG2 4.28Å; L76-T320 HydrophobicContact CG-CG2 4.17Å; L76-E322 HydrophobicContact CD1-CB 4.07Å
77Y96.1Very high96.2Very high51 Ų5152.1 Ų52.120%0.227%0.267CS..  trans-131.3128.6-174-58.3-68.1000110.1F75 D79 V80 R89 M356 K357F75-Y77 VanDerWaalsContact CD2-C 3.5Å; F75-Y77 WeakPolarHBondContact CD2-O 3.28Å; Y77-D79 WeakPolarHBondContact CB-OD1 3.41Å; Y77-D79 PolarHBondContact O-N 3.45Å; Y77-D79 VanDerWaalsContact O-N 3.16Å; Y77-V80 HydrophobicContact CD2-CG2 4.47Å; Y77-V80 PolarHBondContact O-N 3.03Å; Y77-V80 VanDerWaalsContact O-O 3.13Å; Y77-R89 VanDerWaalsContact CD2-NE 3.34Å; Y77-M356 HydrophobicContact CE2-CB 4.46Å; Y77-K357 HydrophobicContact CE2-CD 4.45Å; Y77-K357 WeakPolarHBondContact OH-CD 3.23Å; Y77-K357 VanDerWaalsContact OH-CE 3.24Å; Y77-K357 WeakPolarHBondContact OH-CE 3.16Å; Y77-K357 PolarHBondContact OH-NZ 3.25Å
78P95.5Very high96.4Very high106 Ų10654.7 Ų54.769%0.68828%0.277SS*.THydrogen-bonded Turntrans-58.9-27.7178.3-25.433.7000113.9F75 V80F75-P78 HydrophobicContact CE2-CB 4.27Å; F75-P78 HydrophobicContact CE2-CG 4.14Å; P78-V80 VanDerWaalsContact C-N 3.31Å
79D95.6Very high96.7Very high68 Ų6850.8 Ų50.836%0.36425%0.253SS..THydrogen-bonded Turntrans-86.35.7176.768-23.9000113.9Y77 R89 K92Y77-D79 WeakPolarHBondContact CB-OD1 3.41Å; Y77-D79 PolarHBondContact O-N 3.45Å; Y77-D79 VanDerWaalsContact O-N 3.16Å; D79-R89 IonicContact OD1-CZ 2.73Å; D79-R89 IonicContact OD1-NH1 2.73Å; D79-R89 PolarHBondContact OD1-NH1 3.05Å; D79-R89 IonicContact OD2-NH1 3.88Å; D79-R89 PolarHBondContact OD2-NH1 2.81Å; D79-K92 IonicContact OD2-NZ 2.72Å; D79-K92 PolarHBondContact OD2-NZ 2.83Å
80V97.9Very high96.9Very high1 Ų145.1 Ų45.11%0.00622%0.223CC..  trans-12698.6173.3-177.80000109.3Y77 P78 D85 A86 R89 V316 M356Y77-V80 HydrophobicContact CD2-CG2 4.47Å; Y77-V80 PolarHBondContact O-N 3.03Å; Y77-V80 VanDerWaalsContact O-O 3.13Å; P78-V80 VanDerWaalsContact C-N 3.31Å; V80-D85 HydrophobicContact CB-CB 4.29Å; V80-D85 HydrophobicContact CG1-CB 4.1Å; V80-D85 HydrophobicContact CG2-CB 4.37Å; V80-A86 HydrophobicContact CG1-CB 4.13Å; V80-R89 HydrophobicContact CG2-CB 3.72Å; V80-R89 HydrophobicContact CG2-CG 4.11Å; V80-V316 HydrophobicContact CG1-CG2 4.46Å; V80-V316 WeakPolarHBondContact O-CG1 3.46Å; V80-M356 HydrophobicContact CB-SD 4.47Å; V80-M356 HydrophobicContact CG1-CG 3.97Å; V80-M356 HydrophobicContact CG1-SD 3.63Å
81R98Very high97.2Very high98 Ų9846.5 Ų46.537%0.3722%0.223SC..SBendtrans-115-12.7178.6-56.6-58.1-60.7-106.7-2.8112.1D85 P289R81-D85 PolarHBondContact N-OD2 3.34Å; R81-P289 HydrophobicContact CB-CG 3.8Å
82T98.5Very high97.3Very high3 Ų346.6 Ų46.62%0.01822%0.222CC..SBendtrans-133.2163.6174.969.50000112.7Y84 D85 A86 P287 P289 H312T82-Y84 PolarHBondContact O-N 2.89Å; T82-Y84 WeakPolarHBondContact OG1-CB 3.42Å; T82-Y84 PolarHBondContact OG1-N 3.32Å; T82-D85 PolarHBondContact N-OD2 3.07Å; T82-D85 WeakPolarHBondContact O-CB 3.47Å; T82-D85 PolarHBondContact O-N 3.32Å; T82-D85 VanDerWaalsContact O-N 3.11Å; T82-D85 PolarHBondContact OG1-N 3.14Å; T82-D85 VanDerWaalsContact OG1-N 3.13Å; T82-D85 PolarHBondContact OG1-OD1 2.81Å; T82-D85 PolarHBondContact OG1-OD2 3.48Å; T82-A86 PolarHBondContact O-N 3.43Å; T82-P287 HydrophobicContact CG2-CG 4.36Å; T82-P287 WeakPolarHBondContact CG2-O 3.44Å; T82-P289 HydrophobicContact CG2-CG 4.41Å; T82-H312 HydrophobicContact CG2-CB 3.89Å
83V97.4Very high97.2Very high1 Ų147.4 Ų47.41%0.00623%0.228CC..Hα-helixtrans-62.7-29.1170.7-177.80000111.3D85 A86 Y173 H312 I315 I352V83-D85 VanDerWaalsContact C-N 3.32Å; V83-D85 PolarHBondContact O-N 2.79Å; V83-A86 WeakPolarHBondContact O-CB 3.34Å; V83-A86 PolarHBondContact O-N 2.97Å; V83-Y173 HydrophobicContact CB-CE2 4.12Å; V83-Y173 HydrophobicContact CG1-CD2 4.35Å; V83-Y173 HydrophobicContact CG1-CE2 3.65Å; V83-H312 PolarHBondContact N-ND1 2.9Å; V83-I315 HydrophobicContact CG2-CB 4.09Å; V83-I315 HydrophobicContact CG2-CD1 4.23Å; V83-I315 HydrophobicContact CG2-CG2 3.85Å; V83-I352 HydrophobicContact CG1-CD1 3.92Å; V83-I352 HydrophobicContact CG1-CG1 4.05Å; V83-I352 HydrophobicContact CG2-CD1 4.02Å
84Y98.1Very high97.2Very high22 Ų2245.8 Ų45.89%0.08622%0.223CC..Hα-helixtrans-63.4-36.9172.6176.3-88.3000112.4T82 R88 V174 P286T82-Y84 PolarHBondContact O-N 2.89Å; T82-Y84 WeakPolarHBondContact OG1-CB 3.42Å; T82-Y84 PolarHBondContact OG1-N 3.32Å; Y84-R88 VanDerWaalsContact CE2-NH2 3.26Å; Y84-R88 VanDerWaalsContact CZ-NH1 3.26Å; Y84-R88 VanDerWaalsContact CZ-NH2 3.31Å; Y84-R88 PolarHBondContact O-NH1 2.86Å; Y84-R88 PolarHBondContact OH-NE 3.45Å; Y84-R88 PolarHBondContact OH-NH2 3.02Å; Y84-R88 VanDerWaalsContact OH-NH2 3.15Å; Y84-V174 HydrophobicContact CE2-CG2 4.4Å; Y84-P286 HydrophobicContact CD1-CB 3.69Å; Y84-P286 HydrophobicContact CD2-CB 4.4Å; Y84-P286 HydrophobicContact CE1-CB 3.46Å; Y84-P286 VanDerWaalsContact CE1-CB 3.46Å; Y84-P286 HydrophobicContact CE1-CG 4.28Å; Y84-P286 HydrophobicContact CE2-CB 4.2Å; Y84-P286 HydrophobicContact CG-CB 4.15Å
85D98.3Very high97.2Very high44 Ų4448.5 Ų48.524%0.23524%0.238CC..Hα-helixtrans-71.7-34.3176-56.6-37.9000111.8V80 R81 T82 V83 I87 R88 R89V80-D85 HydrophobicContact CB-CB 4.29Å; V80-D85 HydrophobicContact CG1-CB 4.1Å; V80-D85 HydrophobicContact CG2-CB 4.37Å; R81-D85 PolarHBondContact N-OD2 3.34Å; T82-D85 PolarHBondContact N-OD2 3.07Å; T82-D85 WeakPolarHBondContact O-CB 3.47Å; T82-D85 PolarHBondContact O-N 3.32Å; T82-D85 VanDerWaalsContact O-N 3.11Å; T82-D85 PolarHBondContact OG1-N 3.14Å; T82-D85 VanDerWaalsContact OG1-N 3.13Å; T82-D85 PolarHBondContact OG1-OD1 2.81Å; T82-D85 PolarHBondContact OG1-OD2 3.48Å; V83-D85 VanDerWaalsContact C-N 3.32Å; V83-D85 PolarHBondContact O-N 2.79Å; D85-I87 PolarHBondContact O-N 3.13Å; D85-R88 CarbonylContact O-C 3.47Å; D85-R88 PolarHBondContact O-N 2.96Å; D85-R88 VanDerWaalsContact O-N 3.15Å; D85-R89 WeakPolarHBondContact O-CB 3.33Å; D85-R89 PolarHBondContact O-N 2.54Å
86A97.6Very high97.2Very high0 Ų049.2 Ų49.20%025%0.245CC..Hα-helixtrans-55.9-51.3-174.900000112.7V80 T82 V83 R88 R89 G90 I352 M355 M356V80-A86 HydrophobicContact CG1-CB 4.13Å; T82-A86 PolarHBondContact O-N 3.43Å; V83-A86 WeakPolarHBondContact O-CB 3.34Å; V83-A86 PolarHBondContact O-N 2.97Å; A86-R88 VanDerWaalsContact C-N 3.33Å; A86-R88 PolarHBondContact O-N 3.42Å; A86-R89 WeakPolarHBondContact O-CB 3.4Å; A86-R89 PolarHBondContact O-N 3.11Å; A86-G90 PolarHBondContact O-N 2.93Å; A86-G90 VanDerWaalsContact O-N 3.12Å; A86-I352 HydrophobicContact CB-CG2 4.26Å; A86-M355 CarbonylContact O-C 3.55Å; A86-M356 HydrophobicContact CB-CG 3.37Å; A86-M356 HydrophobicContact CB-SD 4.37Å
87I96.2Very high97.2Very high1 Ų148 Ų481%0.00524%0.242CC..Hα-helixtrans-67.7-33.9179-164.3169.3000112.3D85 G90 L91 Y118 V121 I122 Q170 M355D85-I87 PolarHBondContact O-N 3.13Å; I87-G90 PolarHBondContact O-N 2.86Å; I87-L91 PolarHBondContact O-N 3.04Å; I87-Y118 HydrophobicContact CG1-CD1 3.8Å; I87-Y118 HydrophobicContact CG1-CE1 4.05Å; I87-Y118 WeakPolarHBondContact O-CD1 3.5Å; I87-V121 HydrophobicContact CD1-CB 4.42Å; I87-V121 HydrophobicContact CD1-CG1 3.65Å; I87-I122 HydrophobicContact CD1-CG1 4.33Å; I87-I122 HydrophobicContact CG1-CD1 4.46Å; I87-I122 HydrophobicContact CG1-CG1 4.3Å; I87-I122 HydrophobicContact CG2-CD1 4.46Å; I87-I122 HydrophobicContact CG2-CG1 4.25Å; I87-Q170 HydrophobicContact CD1-CG 4.02Å; I87-M355 HydrophobicContact CB-SD 4.27Å; I87-M355 HydrophobicContact CD1-SD 4.27Å; I87-M355 HydrophobicContact CG1-SD 4.31Å
88R97.9Very high97.2Very high55 Ų5547.8 Ų47.821%0.20825%0.247CC..Hα-helixtrans-71.1-33.2177.5-74.6175.4172.367.67.2112.2Y84 D85 A86 L91 K92 I122 E126Y84-R88 VanDerWaalsContact CE2-NH2 3.26Å; Y84-R88 VanDerWaalsContact CZ-NH1 3.26Å; Y84-R88 VanDerWaalsContact CZ-NH2 3.31Å; Y84-R88 PolarHBondContact O-NH1 2.86Å; Y84-R88 PolarHBondContact OH-NE 3.45Å; Y84-R88 PolarHBondContact OH-NH2 3.02Å; Y84-R88 VanDerWaalsContact OH-NH2 3.15Å; D85-R88 CarbonylContact O-C 3.47Å; D85-R88 PolarHBondContact O-N 2.96Å; D85-R88 VanDerWaalsContact O-N 3.15Å; A86-R88 VanDerWaalsContact C-N 3.33Å; A86-R88 PolarHBondContact O-N 3.42Å; R88-L91 WeakPolarHBondContact O-CB 3.23Å; R88-L91 PolarHBondContact O-N 3.21Å; R88-K92 PolarHBondContact O-N 3.41Å; R88-K92 VanDerWaalsContact O-N 3.12Å; R88-I122 HydrophobicContact CG-CD1 4.07Å; R88-E126 IonicContact NH2-OE1 2.72Å; R88-E126 PolarHBondContact NH2-OE1 2.98Å
89R97.9Very high97.2Very high43 Ų4342.7 Ų42.716%0.16221%0.214CC..Hα-helixtrans-62.4-45.6167.8177172.1179.269.46.6110.7Y77 D79 V80 D85 A86 L91 K92 V93 M356Y77-R89 VanDerWaalsContact CD2-NE 3.34Å; D79-R89 IonicContact OD1-CZ 2.73Å; D79-R89 IonicContact OD1-NH1 2.73Å; D79-R89 PolarHBondContact OD1-NH1 3.05Å; D79-R89 IonicContact OD2-NH1 3.88Å; D79-R89 PolarHBondContact OD2-NH1 2.81Å; V80-R89 HydrophobicContact CG2-CB 3.72Å; V80-R89 HydrophobicContact CG2-CG 4.11Å; D85-R89 WeakPolarHBondContact O-CB 3.33Å; D85-R89 PolarHBondContact O-N 2.54Å; A86-R89 WeakPolarHBondContact O-CB 3.4Å; A86-R89 PolarHBondContact O-N 3.11Å; R89-L91 VanDerWaalsContact C-N 3.31Å; R89-L91 PolarHBondContact O-N 3.38Å; R89-K92 PolarHBondContact O-N 3.23Å; R89-K92 VanDerWaalsContact O-N 3.13Å; R89-V93 HydrophobicContact CG-CG2 3.92Å; R89-V93 WeakPolarHBondContact O-CB 3.12Å; R89-V93 WeakPolarHBondContact O-CG2 3.23Å; R89-V93 PolarHBondContact O-N 3.4Å; R89-M356 VanDerWaalsContact CD-O 3.28Å; R89-M356 WeakPolarHBondContact CD-O 3.44Å; R89-M356 WeakPolarHBondContact CG-O 3.29Å; R89-M356 PolarHBondContact NE-O 2.97Å
90G97.3Very high97.1Very high0 Ų039.5 Ų39.50%020%0.197CC..Hα-helixtrans-54.4-45.2174.900000112.8A86 I87 K92 V93 T94 M355A86-G90 PolarHBondContact O-N 2.93Å; A86-G90 VanDerWaalsContact O-N 3.12Å; I87-G90 PolarHBondContact O-N 2.86Å; G90-K92 PolarHBondContact O-N 3.42Å; G90-V93 PolarHBondContact O-N 3.35Å; G90-T94 WeakPolarHBondContact O-CB 3.14Å; G90-T94 VanDerWaalsContact O-CG2 3.31Å; G90-T94 WeakPolarHBondContact O-CG2 3.36Å; G90-T94 PolarHBondContact O-N 2.87Å; G90-T94 VanDerWaalsContact O-N 3.09Å; G90-T94 PolarHBondContact O-OG1 3.43Å; G90-M355 WeakPolarHBondContact CA-O 3.44Å; G90-M355 PolarHBondContact N-O 3.34Å
91L97.8Very high96.8Very high54 Ų5439.4 Ų39.428%0.28320%0.197SC..Hα-helixtrans-54.3-51.4172.9175.465.9000112.1I87 R88 R89 T94 N95 N96 Y118 I122I87-L91 PolarHBondContact O-N 3.04Å; R88-L91 WeakPolarHBondContact O-CB 3.23Å; R88-L91 PolarHBondContact O-N 3.21Å; R89-L91 VanDerWaalsContact C-N 3.31Å; R89-L91 PolarHBondContact O-N 3.38Å; L91-T94 PolarHBondContact O-OG1 3.4Å; L91-N95 WeakPolarHBondContact O-CA 3.41Å; L91-N95 PolarHBondContact O-N 3.41Å; L91-N95 VanDerWaalsContact O-N 3.07Å; L91-N96 HydrophobicContact CD1-CB 3.75Å; L91-N96 WeakPolarHBondContact CD1-OD1 3.33Å; L91-N96 PolarHBondContact O-N 3.32Å; L91-Y118 HydrophobicContact CB-CG 4.5Å; L91-I122 HydrophobicContact CB-CD1 3.92Å; L91-I122 HydrophobicContact CD2-CD1 3.76Å; L91-I122 HydrophobicContact CG-CD1 4.34Å
92K97.6Very high96.4Very high142 Ų14235.5 Ų35.562%0.61718%0.182SC*.Hα-helixtrans-65-46.1-178.7173-177160.4-168.30112.6D79 R88 R89 G90 T94 N95D79-K92 IonicContact OD2-NZ 2.72Å; D79-K92 PolarHBondContact OD2-NZ 2.83Å; R88-K92 PolarHBondContact O-N 3.41Å; R88-K92 VanDerWaalsContact O-N 3.12Å; R89-K92 PolarHBondContact O-N 3.23Å; R89-K92 VanDerWaalsContact O-N 3.13Å; G90-K92 PolarHBondContact O-N 3.42Å; K92-T94 VanDerWaalsContact C-N 3.32Å; K92-T94 PolarHBondContact O-N 3.18Å; K92-N95 PolarHBondContact O-N 3.09Å
93V96.6Very high95.8Very high52 Ų5237.3 Ų37.332%0.31519%0.189SC..Hα-helixtrans-67.4-34.3-176.2169.70000111.9R89 G90R89-V93 HydrophobicContact CG-CG2 3.92Å; R89-V93 WeakPolarHBondContact O-CB 3.12Å; R89-V93 WeakPolarHBondContact O-CG2 3.23Å; R89-V93 PolarHBondContact O-N 3.4Å; G90-V93 PolarHBondContact O-N 3.35Å
94T96.8Very high95.2Very high27 Ų2741.2 Ų41.217%0.16621%0.205CC..Hα-helixtrans-91.8-11.7-178.260.40000113.6G90 L91 K92 N96 G97 Y118 K332 G358G90-T94 WeakPolarHBondContact O-CB 3.14Å; G90-T94 VanDerWaalsContact O-CG2 3.31Å; G90-T94 WeakPolarHBondContact O-CG2 3.36Å; G90-T94 PolarHBondContact O-N 2.87Å; G90-T94 VanDerWaalsContact O-N 3.09Å; G90-T94 PolarHBondContact O-OG1 3.43Å; L91-T94 PolarHBondContact O-OG1 3.4Å; K92-T94 VanDerWaalsContact C-N 3.32Å; K92-T94 PolarHBondContact O-N 3.18Å; T94-N96 PolarHBondContact OG1-N 3.43Å; T94-G97 PolarHBondContact OG1-N 3.38Å; T94-Y118 HydrophobicContact CG2-CD2 4.39Å; T94-Y118 HydrophobicContact CG2-CE2 4.12Å; T94-K332 HydrophobicContact CG2-CB 4.17Å; T94-G358 VanDerWaalsContact CG2-CA 3.48Å; T94-G358 WeakPolarHBondContact CG2-O 3.49Å
95N97Very high94.4Very high148 Ų14845 Ų4579%0.79123%0.227SC*.THydrogen-bonded Turntrans53.354.6-166.3-172.149.8000111.3L91 K92L91-N95 WeakPolarHBondContact O-CA 3.41Å; L91-N95 PolarHBondContact O-N 3.41Å; L91-N95 VanDerWaalsContact O-N 3.07Å; K92-N95 PolarHBondContact O-N 3.09Å
96N97Very high93.5Very high76 Ų7644.3 Ų44.341%0.40622%0.224SC..SBendtrans6345.9-177-163.531.7000114.9L91 T94 S117 G119L91-N96 HydrophobicContact CD1-CB 3.75Å; L91-N96 WeakPolarHBondContact CD1-OD1 3.33Å; L91-N96 PolarHBondContact O-N 3.32Å; T94-N96 PolarHBondContact OG1-N 3.43Å; N96-S117 WeakPolarHBondContact OD1-CB 3.48Å; N96-S117 PolarHBondContact OD1-OG 3.24Å; N96-G119 VanDerWaalsContact OD1-CA 3.26Å; N96-G119 WeakPolarHBondContact OD1-CA 3.46Å; N96-G119 PolarHBondContact OD1-N 2.86Å
97G96.2Very high92.7Very high15 Ų1550.4 Ų50.416%0.15526%0.264CS..  trans-71.8177.617400000113.6T94 S117 Y118T94-G97 PolarHBondContact OG1-N 3.38Å; G97-S117 CarbonylContact O-C 3.54Å; G97-S117 WeakPolarHBondContact O-CA 3.19Å; G97-Y118 WeakPolarHBondContact O-CD2 3.49Å; G97-Y118 PolarHBondContact O-N 2.8Å
98P95.9Very high92.1Very high47 Ų4757.3 Ų57.331%0.30530%0.296SS..EExtended strand (participates in β ladder)trans-63.2139.4173.528.5-35.7000111.1W115 Y118 K360P98-W115 HydrophobicContact CB-CB 3.95Å; P98-W115 HydrophobicContact CB-CD2 4.19Å; P98-W115 HydrophobicContact CB-CE3 4.08Å; P98-W115 HydrophobicContact CB-CG 4.16Å; P98-Y118 WeakPolarHBondContact O-CE2 3.2Å; P98-K360 HydrophobicContact CB-CD 4.29Å; P98-K360 HydrophobicContact CB-CG 4.43Å; P98-K360 HydrophobicContact CG-CD 3.62Å; P98-K360 HydrophobicContact CG-CG 4.01Å
99C95.1Very high91.3Very high0 Ų057.3 Ų57.30%031%0.313CS..EExtended strand (participates in β ladder)trans-118.5-67.4-178.4-176.30000110.7L116 Y118 V121 I361C99-L116 PolarHBondContact N-O 3.24Å; C99-Y118 HydrophobicContact CB-CD1 4.02Å; C99-Y118 HydrophobicContact CB-CD2 3.57Å; C99-Y118 HydrophobicContact CB-CE1 4.14Å; C99-Y118 HydrophobicContact CB-CE2 3.67Å; C99-Y118 HydrophobicContact CB-CG 3.71Å; C99-Y118 VanDerWaalsContact SG-CE1 3.51Å; C99-V121 HydrophobicContact CB-CG2 4.23Å; C99-I361 PolarHBondContact O-N 3.07Å
100L93.6Very high90.6Very high0 Ų058.9 Ų58.90%033%0.327CS..EExtended strand (participates in β ladder)trans-113.8124.9-172.8-54.3-179.3000110.5W115 L116 V121 L164 V166 M355 I361 Y363L100-W115 CarbonylContact O-C 3.56Å; L100-W115 WeakPolarHBondContact O-CA 3.04Å; L100-L116 PolarHBondContact N-O 3.36Å; L100-L116 PolarHBondContact O-N 3.35Å; L100-V121 HydrophobicContact CB-CG2 4.34Å; L100-V121 HydrophobicContact CD1-CB 4.49Å; L100-V121 HydrophobicContact CD1-CG1 3.86Å; L100-V121 HydrophobicContact CD1-CG2 3.7Å; L100-V121 HydrophobicContact CG-CG2 3.86Å; L100-L164 HydrophobicContact CB-CD1 3.7Å; L100-L164 HydrophobicContact CD1-CB 4.32Å; L100-L164 HydrophobicContact CD1-CD1 3.54Å; L100-L164 HydrophobicContact CD1-CG 4.47Å; L100-L164 HydrophobicContact CG-CD1 4.26Å; L100-V166 HydrophobicContact CD1-CB 3.81Å; L100-V166 HydrophobicContact CD1-CG1 3.85Å; L100-V166 HydrophobicContact CD1-CG2 4.42Å; L100-M355 HydrophobicContact CD2-CE 4.39Å; L100-I361 CarbonylContact C-O 3.42Å; L100-I361 WeakPolarHBondContact CA-O 3.19Å; L100-I361 HydrophobicContact CD2-CB 4.04Å; L100-I361 HydrophobicContact CD2-CD1 4.03Å; L100-Y363 HydrophobicContact CB-CE2 4.22Å; L100-Y363 HydrophobicContact CD2-CE2 4.08Å
101G92.3Very high90Very high0 Ų063.4 Ų63.40%034%0.344CS..EExtended strand (participates in β ladder)trans-115.3147.5-174.700000112.8A114 W115 I361 G362 Y363G101-A114 CarbonylContact C-O 3.5Å; G101-A114 WeakPolarHBondContact CA-O 3.5Å; G101-W115 VanDerWaalsContact CA-CZ3 3.5Å; G101-I361 PolarHBondContact N-O 2.77Å; G101-G362 WeakPolarHBondContact O-CA 3.35Å; G101-Y363 WeakPolarHBondContact O-CD2 3.35Å; G101-Y363 PolarHBondContact O-N 3.46Å
102Y89.2Confident89.6Confident16 Ų1663.9 Ų63.96%0.06335%0.351CS..EExtended strand (participates in β ladder)trans-152.7155.9-177.666.2-85.3000115.3K104 Y113 A114 P153 D162Y102-K104 HydrophobicContact CD2-CB 4.15Å; Y102-K104 HydrophobicContact CE2-CB 3.64Å; Y102-K104 HydrophobicContact CE2-CD 4.11Å; Y102-K104 HydrophobicContact CE2-CG 4.01Å; Y102-K104 PolarHBondContact O-N 3.41Å; Y102-K104 VanDerWaalsContact O-N 3.16Å; Y102-Y113 CarbonylContact O-C 2.99Å; Y102-Y113 VanDerWaalsContact O-CA 3.22Å; Y102-Y113 WeakPolarHBondContact O-CA 3.34Å; Y102-A114 HydrophobicContact CD1-CB 4.37Å; Y102-A114 WeakPolarHBondContact CD1-O 3.01Å; Y102-A114 HydrophobicContact CE1-CB 3.79Å; Y102-A114 HydrophobicContact CE2-CB 3.97Å; Y102-A114 PolarHBondContact N-O 3.39Å; Y102-A114 PolarHBondContact O-N 2.76Å; Y102-P153 VanDerWaalsContact CB-CG 3.46Å; Y102-P153 HydrophobicContact CG-CB 4.11Å; Y102-D162 HydrophobicContact CD1-CB 4.35Å; Y102-D162 HydrophobicContact CE1-CB 3.96Å; Y102-D162 WeakPolarHBondContact CE1-OD2 3.43Å; Y102-D162 WeakPolarHBondContact CE2-OD1 3.42Å; Y102-D162 PolarHBondContact OH-OD1 2.94Å; Y102-D162 PolarHBondContact OH-OD2 3.31Å
103R87.2Confident89.3Confident41 Ų4158.6 Ų58.616%0.15533%0.327CS..EExtended strand (participates in β ladder)trans-75.797178.6-59.7-67.8-57.5-111.815.2110.9R111 P112 Y113 D373 D374R103-R111 HydrophobicContact CB-CB 4.35Å; R103-R111 PolarHBondContact NE-O 2.81Å; R103-R111 PolarHBondContact NH2-O 3.46Å; R103-P112 WeakPolarHBondContact CA-O 3.37Å; R103-Y113 HydrophobicContact CG-CE1 4.41Å; R103-Y113 HydrophobicContact CG-CE2 4.25Å; R103-D373 PolarHBondContact NH1-O 3.19Å; R103-D374 IonicContact CZ-OD1 3.12Å; R103-D374 IonicContact NE-OD1 3.4Å; R103-D374 VanDerWaalsContact NH1-CA 3.34Å; R103-D374 IonicContact NH1-OD1 3.41Å; R103-D374 PolarHBondContact NH1-OD1 2.8Å
104K83.3Confident89.1Confident83 Ų8357.4 Ų57.436%0.36132%0.323SS..PPolyproline II helixtrans-88.4124.8177.8-169.2168.9-173.1161.30111.1Y102 T106 R111 P112 A114 D160Y102-K104 HydrophobicContact CD2-CB 4.15Å; Y102-K104 HydrophobicContact CE2-CB 3.64Å; Y102-K104 HydrophobicContact CE2-CD 4.11Å; Y102-K104 HydrophobicContact CE2-CG 4.01Å; Y102-K104 PolarHBondContact O-N 3.41Å; Y102-K104 VanDerWaalsContact O-N 3.16Å; K104-T106 PolarHBondContact O-N 3.43Å; K104-R111 VanDerWaalsContact O-CA 3.28Å; K104-R111 WeakPolarHBondContact O-CA 3.27Å; K104-P112 PolarHBondContact N-O 3.47Å; K104-P112 WeakPolarHBondContact O-CD 3.25Å; K104-A114 HydrophobicContact CB-CB 3.94Å; K104-A114 HydrophobicContact CD-CB 4.08Å; K104-D160 IonicContact NZ-OD1 3.76Å
105L81.7Confident88.9Confident102 Ų10260 Ų6053%0.53433%0.329SS..PPolyproline II helixtrans-70.8122.8174.1-177.666.5000110.4T110 R111L105-T110 WeakPolarHBondContact CA-O 3.48Å; L105-R111 HydrophobicContact CB-CG 4.36Å; L105-R111 HydrophobicContact CD1-CG 3.82Å
106T80.6Confident88.6Confident28 Ų2853.4 Ų53.417%0.17229%0.294CS..PPolyproline II helixtrans-90.5159.8174.979.40000111.1K104 E108 G109 T110 P112K104-T106 PolarHBondContact O-N 3.43Å; T106-E108 WeakPolarHBondContact CB-OE2 3.42Å; T106-E108 PolarHBondContact O-N 2.79Å; T106-E108 VanDerWaalsContact O-N 3.13Å; T106-E108 PolarHBondContact OG1-N 2.82Å; T106-E108 PolarHBondContact OG1-OE2 3.46Å; T106-G109 PolarHBondContact O-N 3.39Å; T106-T110 WeakPolarHBondContact CG2-OG1 3.26Å; T106-T110 PolarHBondContact N-O 3Å; T106-T110 PolarHBondContact OG1-N 3.48Å; T106-T110 PolarHBondContact OG1-OG1 2.92Å; T106-P112 VanDerWaalsContact CG2-CD 3.41Å; T106-P112 HydrophobicContact CG2-CG 3.72Å
107P80.7Confident88.6Confident129 Ų12950.7 Ų50.784%0.83828%0.281SS*.THydrogen-bonded Turntrans-54.7-28.1173.9-26.236000113.8G109P107-G109 PolarHBondContact O-N 3.17Å
108E83.3Confident88.5Confident145 Ų14550 Ų5068%0.67827%0.273SS*.THydrogen-bonded Turntrans-77.90.8177.6-53.471.2-148.700113.1T106 T110T106-E108 WeakPolarHBondContact CB-OE2 3.42Å; T106-E108 PolarHBondContact O-N 2.79Å; T106-E108 VanDerWaalsContact O-N 3.13Å; T106-E108 PolarHBondContact OG1-N 2.82Å; T106-E108 PolarHBondContact OG1-OE2 3.46Å; E108-T110 VanDerWaalsContact C-N 3.26Å; E108-T110 HydrophobicContact CB-CG2 4.5Å; E108-T110 PolarHBondContact O-N 3Å
109G80.8Confident88.5Confident55 Ų5548.6 Ų48.657%0.56727%0.268SS*.SBendtrans79.24.7-17900000114.3T106 P107T106-G109 PolarHBondContact O-N 3.39Å; P107-G109 PolarHBondContact O-N 3.17Å
110T82.9Confident88.5Confident77 Ų7752.7 Ų52.747%0.47229%0.287SS..  trans-81.3160.8173.274.10000110.8L105 T106 E108L105-T110 WeakPolarHBondContact CA-O 3.48Å; T106-T110 WeakPolarHBondContact CG2-OG1 3.26Å; T106-T110 PolarHBondContact N-O 3Å; T106-T110 PolarHBondContact OG1-N 3.48Å; T106-T110 PolarHBondContact OG1-OG1 2.92Å; E108-T110 VanDerWaalsContact C-N 3.26Å; E108-T110 HydrophobicContact CB-CG2 4.5Å; E108-T110 PolarHBondContact O-N 3Å
111R85.3Confident88.5Confident94 Ų9452.7 Ų52.736%0.35529%0.287SS..  trans-129.872.3176.2-64.1-174.9-177-156-4111.1R103 K104 L105 E154R103-R111 HydrophobicContact CB-CB 4.35Å; R103-R111 PolarHBondContact NE-O 2.81Å; R103-R111 PolarHBondContact NH2-O 3.46Å; K104-R111 VanDerWaalsContact O-CA 3.28Å; K104-R111 WeakPolarHBondContact O-CA 3.27Å; L105-R111 HydrophobicContact CB-CG 4.36Å; L105-R111 HydrophobicContact CD1-CG 3.82Å; R111-E154 IonicContact NH1-OE1 2.97Å
112P89.5Confident88.6Confident64 Ų6453.4 Ų53.442%0.41629%0.291SS..PPolyproline II helixtrans-68.5165.2173.131.2-35.2000111.4R103 K104 T106R103-P112 WeakPolarHBondContact CA-O 3.37Å; K104-P112 PolarHBondContact N-O 3.47Å; K104-P112 WeakPolarHBondContact O-CD 3.25Å; T106-P112 VanDerWaalsContact CG2-CD 3.41Å; T106-P112 HydrophobicContact CG2-CG 3.72Å
113Y91.1Very high88.9Confident32 Ų3258.3 Ų58.313%0.12532%0.315CS..EExtended strand (participates in β ladder)trans-76.4120.6167.9-85.9-90.8000110.2Y102 R103 Y363 A377 L378Y102-Y113 CarbonylContact O-C 2.99Å; Y102-Y113 VanDerWaalsContact O-CA 3.22Å; Y102-Y113 WeakPolarHBondContact O-CA 3.34Å; R103-Y113 HydrophobicContact CG-CE1 4.41Å; R103-Y113 HydrophobicContact CG-CE2 4.25Å; Y113-Y363 WeakPolarHBondContact CE1-O 3.3Å; Y113-Y363 PolarHBondContact OH-O 2.83Å; Y113-A377 HydrophobicContact CD2-CB 4.15Å; Y113-A377 HydrophobicContact CE2-CB 4.01Å; Y113-L378 HydrophobicContact CD1-CD1 3.83Å; Y113-L378 HydrophobicContact CD2-CB 4.06Å; Y113-L378 HydrophobicContact CD2-CD1 4.03Å; Y113-L378 HydrophobicContact CE1-CB 4.48Å; Y113-L378 HydrophobicContact CE1-CD1 3.76Å; Y113-L378 HydrophobicContact CE1-CD2 4.39Å; Y113-L378 HydrophobicContact CE1-CG 4.43Å; Y113-L378 HydrophobicContact CE2-CB 3.42Å; Y113-L378 VanDerWaalsContact CE2-CB 3.42Å; Y113-L378 HydrophobicContact CE2-CD1 3.96Å; Y113-L378 HydrophobicContact CE2-CG 4.19Å; Y113-L378 HydrophobicContact CG-CD1 3.97Å
114A91.1Very high89.3Confident26 Ų2657 Ų5722%0.21531%0.312CS..EExtended strand (participates in β ladder)trans-94.6155162.200000108.9G101 Y102 K104G101-A114 CarbonylContact C-O 3.5Å; G101-A114 WeakPolarHBondContact CA-O 3.5Å; Y102-A114 HydrophobicContact CD1-CB 4.37Å; Y102-A114 WeakPolarHBondContact CD1-O 3.01Å; Y102-A114 HydrophobicContact CE1-CB 3.79Å; Y102-A114 HydrophobicContact CE2-CB 3.97Å; Y102-A114 PolarHBondContact N-O 3.39Å; Y102-A114 PolarHBondContact O-N 2.76Å; K104-A114 HydrophobicContact CB-CB 3.94Å; K104-A114 HydrophobicContact CD-CB 4.08Å
115W92.2Very high89.8Confident82 Ų8253.2 Ų53.231%0.31130%0.295SS..EExtended strand (participates in β ladder)trans-132.8130.9-172.6-6790.1000110.6P98 L100 G101 I335 K360 L378P98-W115 HydrophobicContact CB-CB 3.95Å; P98-W115 HydrophobicContact CB-CD2 4.19Å; P98-W115 HydrophobicContact CB-CE3 4.08Å; P98-W115 HydrophobicContact CB-CG 4.16Å; L100-W115 CarbonylContact O-C 3.56Å; L100-W115 WeakPolarHBondContact O-CA 3.04Å; G101-W115 VanDerWaalsContact CA-CZ3 3.5Å; W115-I335 HydrophobicContact CH2-CG2 4.04Å; W115-K360 HydrophobicContact CE3-CB 4.39Å; W115-K360 HydrophobicContact CH2-CB 3.77Å; W115-K360 HydrophobicContact CZ3-CB 3.56Å; W115-K360 HydrophobicContact CZ3-CG 4.38Å; W115-L378 HydrophobicContact CH2-CD1 3.85Å; W115-L378 HydrophobicContact CZ2-CD1 3.69Å
116L92.4Very high90.5Very high10 Ų1050.7 Ų50.75%0.05228%0.281CS..EExtended strand (participates in β ladder)trans-85.6136.2161.5-62.1-178.3000109.4C99 L100 E120 V121 D162 L164 I167C99-L116 PolarHBondContact N-O 3.24Å; L100-L116 PolarHBondContact N-O 3.36Å; L100-L116 PolarHBondContact O-N 3.35Å; L116-E120 HydrophobicContact CB-CB 4.45Å; L116-E120 HydrophobicContact CD2-CB 4.46Å; L116-V121 HydrophobicContact CB-CG2 3.79Å; L116-V121 HydrophobicContact CD1-CG2 4.09Å; L116-D162 HydrophobicContact CD1-CB 4.12Å; L116-D162 WeakPolarHBondContact CD2-OD2 3.37Å; L116-L164 HydrophobicContact CD1-CD1 3.66Å; L116-I167 HydrophobicContact CD1-CD1 4.36Å
117S95.4Very high91.2Very high18 Ų1849.4 Ų49.413%0.12627%0.273CS..EExtended strand (participates in β ladder)trans-71159.6169.465.30000112N96 G97 G119 E120 V121N96-S117 WeakPolarHBondContact OD1-CB 3.48Å; N96-S117 PolarHBondContact OD1-OG 3.24Å; G97-S117 CarbonylContact O-C 3.54Å; G97-S117 WeakPolarHBondContact O-CA 3.19Å; S117-G119 PolarHBondContact O-N 3.19Å; S117-E120 VanDerWaalsContact CB-OE2 3.29Å; S117-E120 WeakPolarHBondContact CB-OE2 3.48Å; S117-E120 PolarHBondContact N-OE2 2.8Å; S117-E120 PolarHBondContact O-N 3.44Å; S117-E120 VanDerWaalsContact OG-CD 3.31Å; S117-E120 VanDerWaalsContact OG-CG 3.31Å; S117-E120 WeakPolarHBondContact OG-CG 3.3Å; S117-E120 PolarHBondContact OG-N 2.85Å; S117-E120 PolarHBondContact OG-OE2 2.87Å; S117-V121 WeakPolarHBondContact O-CG2 2.92Å; S117-V121 PolarHBondContact O-N 2.92Å
118Y95.4Very high91.9Very high0 Ų043.3 Ų43.30%023%0.233CC..Hα-helixtrans-53.6-38.8174.7-86.1-88.6000112.5I87 L91 T94 G97 P98 C99 V121 I122 G358 S359I87-Y118 HydrophobicContact CG1-CD1 3.8Å; I87-Y118 HydrophobicContact CG1-CE1 4.05Å; I87-Y118 WeakPolarHBondContact O-CD1 3.5Å; L91-Y118 HydrophobicContact CB-CG 4.5Å; T94-Y118 HydrophobicContact CG2-CD2 4.39Å; T94-Y118 HydrophobicContact CG2-CE2 4.12Å; G97-Y118 WeakPolarHBondContact O-CD2 3.49Å; G97-Y118 PolarHBondContact O-N 2.8Å; P98-Y118 WeakPolarHBondContact O-CE2 3.2Å; C99-Y118 HydrophobicContact CB-CD1 4.02Å; C99-Y118 HydrophobicContact CB-CD2 3.57Å; C99-Y118 HydrophobicContact CB-CE1 4.14Å; C99-Y118 HydrophobicContact CB-CE2 3.67Å; C99-Y118 HydrophobicContact CB-CG 3.71Å; C99-Y118 VanDerWaalsContact SG-CE1 3.51Å; Y118-V121 PolarHBondContact O-N 2.82Å; Y118-I122 WeakPolarHBondContact O-CB 3.42Å; Y118-I122 WeakPolarHBondContact O-CD1 3.06Å; Y118-I122 VanDerWaalsContact O-CG1 3.25Å; Y118-I122 WeakPolarHBondContact O-CG1 3.45Å; Y118-I122 PolarHBondContact O-N 2.92Å; Y118-G358 VanDerWaalsContact OH-C 3.23Å; Y118-G358 VanDerWaalsContact OH-CA 3.27Å; Y118-G358 WeakPolarHBondContact OH-CA 2.83Å; Y118-S359 PolarHBondContact OH-N 3.33Å; Y118-S359 PolarHBondContact OH-O 2.93Å
119G96.3Very high92.6Very high19 Ų1936.4 Ų36.420%0.19620%0.201CC..Hα-helixtrans-68.2-44.2179.600000112.2N96 S117 V121 I122 E123N96-G119 VanDerWaalsContact OD1-CA 3.26Å; N96-G119 WeakPolarHBondContact OD1-CA 3.46Å; N96-G119 PolarHBondContact OD1-N 2.86Å; S117-G119 PolarHBondContact O-N 3.19Å; G119-V121 VanDerWaalsContact C-N 3.31Å; G119-V121 PolarHBondContact O-N 2.65Å; G119-I122 PolarHBondContact O-N 3.4Å; G119-E123 VanDerWaalsContact O-CB 3.3Å; G119-E123 WeakPolarHBondContact O-CB 3.45Å; G119-E123 PolarHBondContact O-N 3.49Å
120E94.2Very high93.4Very high86 Ų8636.2 Ų36.240%0.40219%0.185SC..Hα-helixtrans-62.3-39.2175.2-73.6162.2136.800111.7L116 S117 S124L116-E120 HydrophobicContact CB-CB 4.45Å; L116-E120 HydrophobicContact CD2-CB 4.46Å; S117-E120 VanDerWaalsContact CB-OE2 3.29Å; S117-E120 WeakPolarHBondContact CB-OE2 3.48Å; S117-E120 PolarHBondContact N-OE2 2.8Å; S117-E120 PolarHBondContact O-N 3.44Å; S117-E120 VanDerWaalsContact OG-CD 3.31Å; S117-E120 VanDerWaalsContact OG-CG 3.31Å; S117-E120 WeakPolarHBondContact OG-CG 3.3Å; S117-E120 PolarHBondContact OG-N 2.85Å; S117-E120 PolarHBondContact OG-OE2 2.87Å; E120-S124 VanDerWaalsContact O-CB 3.26Å; E120-S124 WeakPolarHBondContact O-CB 3.21Å; E120-S124 PolarHBondContact O-N 3.34Å; E120-S124 PolarHBondContact O-OG 2.89Å
121V93.8Very high94.1Very high0 Ų033.3 Ų33.30%017%0.165CC..Hα-helixtrans-65.4-45.9175.9177.50000110.8I87 C99 L100 L116 S117 Y118 G119 S124 S125 V166 I167I87-V121 HydrophobicContact CD1-CB 4.42Å; I87-V121 HydrophobicContact CD1-CG1 3.65Å; C99-V121 HydrophobicContact CB-CG2 4.23Å; L100-V121 HydrophobicContact CB-CG2 4.34Å; L100-V121 HydrophobicContact CD1-CB 4.49Å; L100-V121 HydrophobicContact CD1-CG1 3.86Å; L100-V121 HydrophobicContact CD1-CG2 3.7Å; L100-V121 HydrophobicContact CG-CG2 3.86Å; L116-V121 HydrophobicContact CB-CG2 3.79Å; L116-V121 HydrophobicContact CD1-CG2 4.09Å; S117-V121 WeakPolarHBondContact O-CG2 2.92Å; S117-V121 PolarHBondContact O-N 2.92Å; Y118-V121 PolarHBondContact O-N 2.82Å; G119-V121 VanDerWaalsContact C-N 3.31Å; G119-V121 PolarHBondContact O-N 2.65Å; V121-S124 PolarHBondContact O-N 2.74Å; V121-S125 WeakPolarHBondContact O-CB 3.29Å; V121-S125 PolarHBondContact O-N 3.35Å; V121-S125 PolarHBondContact O-OG 2.67Å; V121-V166 HydrophobicContact CG1-CG1 4.46Å; V121-I167 HydrophobicContact CG1-CG1 4.14Å
122I95.4Very high94.7Very high14 Ų1428.8 Ų28.87%0.07215%0.148CC..Hα-helixtrans-64-46.9178.3-72.2164000110.8I87 R88 L91 Y118 G119 S124 S125 E126I87-I122 HydrophobicContact CD1-CG1 4.33Å; I87-I122 HydrophobicContact CG1-CD1 4.46Å; I87-I122 HydrophobicContact CG1-CG1 4.3Å; I87-I122 HydrophobicContact CG2-CD1 4.46Å; I87-I122 HydrophobicContact CG2-CG1 4.25Å; R88-I122 HydrophobicContact CG-CD1 4.07Å; L91-I122 HydrophobicContact CB-CD1 3.92Å; L91-I122 HydrophobicContact CD2-CD1 3.76Å; L91-I122 HydrophobicContact CG-CD1 4.34Å; Y118-I122 WeakPolarHBondContact O-CB 3.42Å; Y118-I122 WeakPolarHBondContact O-CD1 3.06Å; Y118-I122 VanDerWaalsContact O-CG1 3.25Å; Y118-I122 WeakPolarHBondContact O-CG1 3.45Å; Y118-I122 PolarHBondContact O-N 2.92Å; G119-I122 PolarHBondContact O-N 3.4Å; I122-S124 PolarHBondContact O-N 3.4Å; I122-S125 WeakPolarHBondContact O-CB 3.12Å; I122-S125 PolarHBondContact O-N 3.44Å; I122-E126 HydrophobicContact CG2-CG 4.44Å; I122-E126 WeakPolarHBondContact O-CG 3.35Å; I122-E126 PolarHBondContact O-N 3.17Å
123E95.3Very high95Very high120 Ų12027.3 Ų27.356%0.56114%0.137SC*.Hα-helixtrans-60.2-45.3178.2-178.8176.5-145.500111.4G119 S125 E126 G127G119-E123 VanDerWaalsContact O-CB 3.3Å; G119-E123 WeakPolarHBondContact O-CB 3.45Å; G119-E123 PolarHBondContact O-N 3.49Å; E123-S125 VanDerWaalsContact C-N 3.29Å; E123-S125 PolarHBondContact O-N 2.92Å; E123-E126 PolarHBondContact O-N 3.01Å; E123-G127 PolarHBondContact O-N 3.32Å
124S94.1Very high95.3Very high13 Ų1331.9 Ų31.99%0.09116%0.159CC..Hα-helixtrans-62.5-38.7176.7-60.80000111.9E120 V121 I122 G127 L128E120-S124 VanDerWaalsContact O-CB 3.26Å; E120-S124 WeakPolarHBondContact O-CB 3.21Å; E120-S124 PolarHBondContact O-N 3.34Å; E120-S124 PolarHBondContact O-OG 2.89Å; V121-S124 PolarHBondContact O-N 2.74Å; I122-S124 PolarHBondContact O-N 3.4Å; S124-G127 PolarHBondContact O-N 2.97Å; S124-L128 WeakPolarHBondContact O-CB 3.25Å; S124-L128 PolarHBondContact O-N 3.49Å
125S95Very high95.5Very high3 Ų331.4 Ų31.42%0.02115%0.153CC..Hα-helixtrans-67.4-42.4177.7-55.20000111.4V121 I122 E123 L128 A129 Q170 A171V121-S125 WeakPolarHBondContact O-CB 3.29Å; V121-S125 PolarHBondContact O-N 3.35Å; V121-S125 PolarHBondContact O-OG 2.67Å; I122-S125 WeakPolarHBondContact O-CB 3.12Å; I122-S125 PolarHBondContact O-N 3.44Å; E123-S125 VanDerWaalsContact C-N 3.29Å; E123-S125 PolarHBondContact O-N 2.92Å; S125-L128 PolarHBondContact O-N 3.41Å; S125-A129 VanDerWaalsContact O-CB 3.3Å; S125-A129 WeakPolarHBondContact O-CB 3.49Å; S125-A129 PolarHBondContact O-N 2.67Å; S125-Q170 WeakPolarHBondContact OG-CB 3.39Å; S125-A171 WeakPolarHBondContact O-CA 3.35Å; S125-A171 VanDerWaalsContact O-CB 3.25Å; S125-A171 WeakPolarHBondContact O-CB 3.47Å
126E96.2Very high95.6Very high50 Ų5029.6 Ų29.623%0.23416%0.159CC..Hα-helixtrans-67.1-38.6175.3-72178.6-177.800112R88 I122 E123 A129 K130 V174R88-E126 IonicContact NH2-OE1 2.72Å; R88-E126 PolarHBondContact NH2-OE1 2.98Å; I122-E126 HydrophobicContact CG2-CG 4.44Å; I122-E126 WeakPolarHBondContact O-CG 3.35Å; I122-E126 PolarHBondContact O-N 3.17Å; E123-E126 PolarHBondContact O-N 3.01Å; E126-A129 PolarHBondContact O-N 3.45Å; E126-K130 VanDerWaalsContact O-CG 3.25Å; E126-K130 WeakPolarHBondContact O-CG 3.41Å; E126-K130 PolarHBondContact O-N 3.13Å; E126-V174 HydrophobicContact CG-CG1 4.31Å; E126-V174 HydrophobicContact CG-CG2 3.98Å
127G96Very high95.6Very high1 Ų129.3 Ų29.31%0.0116%0.158CC..Hα-helixtrans-57.8-54.9171.700000111.4E123 S124 A129 K130 Y131 G275E123-G127 PolarHBondContact O-N 3.32Å; S124-G127 PolarHBondContact O-N 2.97Å; G127-A129 VanDerWaalsContact C-N 3.3Å; G127-A129 PolarHBondContact O-N 3.02Å; G127-K130 PolarHBondContact O-N 2.86Å; G127-Y131 PolarHBondContact O-N 3.01Å; G127-G275 WeakPolarHBondContact O-CA 3.26Å
128L95.5Very high95.5Very high0 Ų032 Ų320%018%0.177CC..Hα-helixtrans-58-42.2178.2-174.559.6000112.4S124 S125 Y131 F132 I167 A171 I221 I245 F268 C271 V272S124-L128 WeakPolarHBondContact O-CB 3.25Å; S124-L128 PolarHBondContact O-N 3.49Å; S125-L128 PolarHBondContact O-N 3.41Å; L128-Y131 WeakPolarHBondContact O-CB 3.24Å; L128-Y131 PolarHBondContact O-N 3.04Å; L128-Y131 VanDerWaalsContact O-N 3.13Å; L128-F132 HydrophobicContact CD1-CD1 4.45Å; L128-F132 HydrophobicContact CD1-CE1 3.64Å; L128-F132 HydrophobicContact CD1-CZ 4.01Å; L128-F132 HydrophobicContact CD2-CE1 4.32Å; L128-F132 HydrophobicContact CD2-CZ 3.84Å; L128-F132 HydrophobicContact CG-CE1 3.65Å; L128-F132 HydrophobicContact CG-CE2 4.27Å; L128-F132 HydrophobicContact CG-CZ 3.49Å; L128-F132 VanDerWaalsContact CG-CZ 3.49Å; L128-F132 WeakPolarHBondContact O-CD1 3.39Å; L128-F132 WeakPolarHBondContact O-CG 3.34Å; L128-F132 PolarHBondContact O-N 3.15Å; L128-I167 HydrophobicContact CD2-CG2 4.28Å; L128-A171 HydrophobicContact CB-CB 3.89Å; L128-A171 HydrophobicContact CD2-CB 3.82Å; L128-A171 HydrophobicContact CG-CB 3.94Å; L128-I221 HydrophobicContact CD2-CD1 4.35Å; L128-I245 HydrophobicContact CD1-CD1 4.34Å; L128-F268 HydrophobicContact CD1-CE2 4.38Å; L128-F268 HydrophobicContact CD2-CE2 3.53Å; L128-F268 HydrophobicContact CD2-CZ 3.7Å; L128-C271 HydrophobicContact CD1-CB 3.95Å; L128-V272 HydrophobicContact CB-CG2 4.14Å; L128-V272 HydrophobicContact CD1-CG2 4.32Å
129A97.2Very high95.5Very high0 Ų035.6 Ų35.60%020%0.2CC..Hα-helixtrans-61.8-44178.200000112.8S125 E126 G127 Y131 F132 L133 A171 V174 Y175S125-A129 VanDerWaalsContact O-CB 3.3Å; S125-A129 WeakPolarHBondContact O-CB 3.49Å; S125-A129 PolarHBondContact O-N 2.67Å; E126-A129 PolarHBondContact O-N 3.45Å; G127-A129 VanDerWaalsContact C-N 3.3Å; G127-A129 PolarHBondContact O-N 3.02Å; A129-Y131 PolarHBondContact O-N 2.81Å; A129-F132 WeakPolarHBondContact O-CB 3.38Å; A129-F132 PolarHBondContact O-N 3.22Å; A129-L133 PolarHBondContact O-N 3.12Å; A129-A171 HydrophobicContact CB-CB 4.2Å; A129-A171 VanDerWaalsContact CB-O 3.27Å; A129-A171 WeakPolarHBondContact CB-O 3.05Å; A129-V174 HydrophobicContact CB-CB 3.57Å; A129-V174 HydrophobicContact CB-CG1 3.86Å; A129-V174 HydrophobicContact CB-CG2 3.88Å; A129-Y175 HydrophobicContact CB-CD2 3.89Å; A129-Y175 HydrophobicContact CB-CE2 3.95Å
130K97.9Very high95.4Very high52 Ų5235.7 Ų35.723%0.22620%0.201CC..Hα-helixtrans-61.5-36.1174-70.2169.6-175.5175.90111.4E126 G127 F132 L133 H134 Y175 G275 I278 A281E126-K130 VanDerWaalsContact O-CG 3.25Å; E126-K130 WeakPolarHBondContact O-CG 3.41Å; E126-K130 PolarHBondContact O-N 3.13Å; G127-K130 PolarHBondContact O-N 2.86Å; K130-F132 VanDerWaalsContact C-N 3.35Å; K130-L133 PolarHBondContact O-N 3.18Å; K130-H134 PolarHBondContact O-N 3.04Å; K130-Y175 HydrophobicContact CG-CE2 4.49Å; K130-G275 WeakPolarHBondContact CD-O 3.08Å; K130-I278 HydrophobicContact CB-CD1 4.26Å; K130-A281 HydrophobicContact CB-CB 4.26Å; K130-A281 HydrophobicContact CD-CB 4.09Å; K130-A281 HydrophobicContact CG-CB 3.75Å
131Y97.3Very high95.4Very high15 Ų1533.9 Ų33.96%0.05919%0.192CC..Hα-helixtrans-66.7-35.1176.5-159.7-98.5000112.7G127 L128 A129 L133 H134 L135 L266 C271 Q274G127-Y131 PolarHBondContact O-N 3.01Å; L128-Y131 WeakPolarHBondContact O-CB 3.24Å; L128-Y131 PolarHBondContact O-N 3.04Å; L128-Y131 VanDerWaalsContact O-N 3.13Å; A129-Y131 PolarHBondContact O-N 2.81Å; Y131-L133 VanDerWaalsContact C-N 3.31Å; Y131-L133 PolarHBondContact O-N 3.48Å; Y131-H134 AromaticContact CE2-CD2 3.99Å; Y131-H134 WeakPolarHBondContact O-CB 3.03Å; Y131-H134 PolarHBondContact O-N 2.83Å; Y131-L135 HydrophobicContact CD1-CD1 3.9Å; Y131-L135 HydrophobicContact CD1-CD2 4.48Å; Y131-L135 HydrophobicContact CD1-CG 3.98Å; Y131-L135 HydrophobicContact CE1-CD1 3.86Å; Y131-L135 HydrophobicContact CE1-CD2 3.84Å; Y131-L135 HydrophobicContact CE1-CG 3.84Å; Y131-L135 WeakPolarHBondContact O-CG 3.47Å; Y131-L135 PolarHBondContact O-N 2.92Å; Y131-L266 HydrophobicContact CE1-CD1 4.21Å; Y131-C271 WeakPolarHBondContact CB-O 3.38Å; Y131-C271 HydrophobicContact CD1-CB 3.47Å; Y131-C271 VanDerWaalsContact CD1-CB 3.47Å; Y131-C271 WeakPolarHBondContact CD2-O 3.39Å; Y131-C271 HydrophobicContact CE1-CB 3.75Å; Y131-C271 WeakPolarHBondContact CE1-SG 3.34Å; Y131-C271 HydrophobicContact CG-CB 3.91Å; Y131-Q274 HydrophobicContact CD2-CB 3.89Å; Y131-Q274 HydrophobicContact CE2-CB 3.65Å; Y131-Q274 HydrophobicContact CE2-CG 4.48Å; Y131-Q274 PolarHBondContact OH-OE1 2.87Å
132F96.8Very high95.2Very high0 Ų039.9 Ų39.90%022%0.224CC..Hα-helixtrans-57.5-45.8172-58.2-25000111.5L128 A129 K130 H134 L135 G136 I137 A171 M177 L219 I221 I245L128-F132 HydrophobicContact CD1-CD1 4.45Å; L128-F132 HydrophobicContact CD1-CE1 3.64Å; L128-F132 HydrophobicContact CD1-CZ 4.01Å; L128-F132 HydrophobicContact CD2-CE1 4.32Å; L128-F132 HydrophobicContact CD2-CZ 3.84Å; L128-F132 HydrophobicContact CG-CE1 3.65Å; L128-F132 HydrophobicContact CG-CE2 4.27Å; L128-F132 HydrophobicContact CG-CZ 3.49Å; L128-F132 VanDerWaalsContact CG-CZ 3.49Å; L128-F132 WeakPolarHBondContact O-CD1 3.39Å; L128-F132 WeakPolarHBondContact O-CG 3.34Å; L128-F132 PolarHBondContact O-N 3.15Å; A129-F132 WeakPolarHBondContact O-CB 3.38Å; A129-F132 PolarHBondContact O-N 3.22Å; K130-F132 VanDerWaalsContact C-N 3.35Å; F132-H134 VanDerWaalsContact C-N 3.31Å; F132-H134 PolarHBondContact O-N 3.06Å; F132-L135 WeakPolarHBondContact O-CB 3.38Å; F132-L135 PolarHBondContact O-N 3.26Å; F132-L135 VanDerWaalsContact O-N 3.16Å; F132-G136 PolarHBondContact O-N 3.46Å; F132-I137 HydrophobicContact CB-CB 4.19Å; F132-I137 HydrophobicContact CB-CG1 4.49Å; F132-I137 VanDerWaalsContact O-CB 3.28Å; F132-I137 WeakPolarHBondContact O-CB 3.26Å; F132-I137 PolarHBondContact O-N 3.37Å; F132-A171 HydrophobicContact CE2-CB 3.85Å; F132-A171 HydrophobicContact CZ-CB 4.23Å; F132-M177 HydrophobicContact CB-CE 4.26Å; F132-M177 HydrophobicContact CD2-SD 4.08Å; F132-L219 HydrophobicContact CD1-CD1 3.87Å; F132-L219 HydrophobicContact CE1-CD1 4.19Å; F132-L219 HydrophobicContact CE1-CD2 4.19Å; F132-I221 HydrophobicContact CE1-CD1 4.33Å; F132-I221 HydrophobicContact CZ-CD1 3.91Å; F132-I245 HydrophobicContact CD1-CD1 4.32Å; F132-I245 HydrophobicContact CE1-CD1 3.84Å
133L97.1Very high95.1Very high33 Ų3340.2 Ų40.217%0.17323%0.227CC..Hα-helixtrans-62.9-39.1176.5-58.2-170000111.9A129 K130 Y131 L135 G136 I137 P139 Y175 M177 P282A129-L133 PolarHBondContact O-N 3.12Å; K130-L133 PolarHBondContact O-N 3.18Å; Y131-L133 VanDerWaalsContact C-N 3.31Å; Y131-L133 PolarHBondContact O-N 3.48Å; L133-L135 VanDerWaalsContact C-N 3.28Å; L133-L135 PolarHBondContact O-N 2.87Å; L133-G136 WeakPolarHBondContact O-CA 3.34Å; L133-G136 PolarHBondContact O-N 3.36Å; L133-I137 VanDerWaalsContact CD2-O 3.27Å; L133-I137 WeakPolarHBondContact CD2-O 3.47Å; L133-P139 HydrophobicContact CD2-CB 4.21Å; L133-P139 HydrophobicContact CD2-CG 4.44Å; L133-Y175 HydrophobicContact CD1-CD1 4.06Å; L133-Y175 HydrophobicContact CD1-CD2 3.84Å; L133-Y175 HydrophobicContact CD1-CE1 3.72Å; L133-Y175 HydrophobicContact CD1-CE2 3.5Å; L133-Y175 VanDerWaalsContact CD1-CE2 3.5Å; L133-Y175 HydrophobicContact CD1-CG 4.12Å; L133-Y175 VanDerWaalsContact CD1-CZ 3.43Å; L133-Y175 HydrophobicContact CD2-CD2 4.34Å; L133-Y175 HydrophobicContact CD2-CG 4.5Å; L133-Y175 HydrophobicContact CG-CD2 4.03Å; L133-Y175 HydrophobicContact CG-CE2 3.96Å; L133-M177 HydrophobicContact CD2-CE 3.76Å; L133-P282 HydrophobicContact CD1-CG 3.53Å
134H96.5Very high95Very high128 Ų12835.3 Ų35.359%0.59320%0.204SC*.Hα-helixtrans-61.5-34.1174.9179.574000113.2K130 Y131 F132 G136 I278K130-H134 PolarHBondContact O-N 3.04Å; Y131-H134 AromaticContact CE2-CD2 3.99Å; Y131-H134 WeakPolarHBondContact O-CB 3.03Å; Y131-H134 PolarHBondContact O-N 2.83Å; F132-H134 VanDerWaalsContact C-N 3.31Å; F132-H134 PolarHBondContact O-N 3.06Å; H134-G136 PolarHBondContact O-N 3.15Å; H134-I278 HydrophobicContact CB-CD1 3.72Å
135L95.6Very high95Very high16 Ų1634.8 Ų34.88%0.08420%0.2CC..THydrogen-bonded Turntrans-72.4-5.9172.5-64.6176.3000113.3Y131 F132 L133 I137 L219 F243 L266Y131-L135 HydrophobicContact CD1-CD1 3.9Å; Y131-L135 HydrophobicContact CD1-CD2 4.48Å; Y131-L135 HydrophobicContact CD1-CG 3.98Å; Y131-L135 HydrophobicContact CE1-CD1 3.86Å; Y131-L135 HydrophobicContact CE1-CD2 3.84Å; Y131-L135 HydrophobicContact CE1-CG 3.84Å; Y131-L135 WeakPolarHBondContact O-CG 3.47Å; Y131-L135 PolarHBondContact O-N 2.92Å; F132-L135 WeakPolarHBondContact O-CB 3.38Å; F132-L135 PolarHBondContact O-N 3.26Å; F132-L135 VanDerWaalsContact O-N 3.16Å; L133-L135 VanDerWaalsContact C-N 3.28Å; L133-L135 PolarHBondContact O-N 2.87Å; L135-I137 HydrophobicContact CB-CG1 4.39Å; L135-L219 HydrophobicContact CD1-CD1 3.96Å; L135-F243 HydrophobicContact CB-CD2 4.5Å; L135-F243 HydrophobicContact CB-CE1 4.29Å; L135-F243 HydrophobicContact CB-CE2 4.11Å; L135-F243 HydrophobicContact CB-CZ 4Å; L135-F243 HydrophobicContact CD1-CD1 4.23Å; L135-F243 HydrophobicContact CD1-CG 4.24Å; L135-F243 HydrophobicContact CD2-CD1 4.22Å; L135-F243 HydrophobicContact CD2-CE1 3.98Å; L135-F243 HydrophobicContact CD2-CZ 4.49Å; L135-F243 WeakPolarHBondContact O-CZ 3.43Å; L135-L266 HydrophobicContact CD1-CD1 3.62Å; L135-L266 HydrophobicContact CD2-CD1 3.75Å; L135-L266 HydrophobicContact CG-CD1 4.35Å
136G94.3Very high94.9Very high43 Ų4334.6 Ų34.644%0.44320%0.199SC..THydrogen-bonded Turntrans78.827-176.100000113.1F132 L133 H134F132-G136 PolarHBondContact O-N 3.46Å; L133-G136 WeakPolarHBondContact O-CA 3.34Å; L133-G136 PolarHBondContact O-N 3.36Å; H134-G136 PolarHBondContact O-N 3.15Å
137I93.5Very high94.6Very high4 Ų432.2 Ų32.22%0.02119%0.188CC..PPolyproline II helixtrans-79.2127.4166.4-58.1-59.6000108.1F132 L133 L135 T143 I145 M177 Q218 L219 F243F132-I137 HydrophobicContact CB-CB 4.19Å; F132-I137 HydrophobicContact CB-CG1 4.49Å; F132-I137 VanDerWaalsContact O-CB 3.28Å; F132-I137 WeakPolarHBondContact O-CB 3.26Å; F132-I137 PolarHBondContact O-N 3.37Å; L133-I137 VanDerWaalsContact CD2-O 3.27Å; L133-I137 WeakPolarHBondContact CD2-O 3.47Å; L135-I137 HydrophobicContact CB-CG1 4.39Å; I137-T143 HydrophobicContact CG2-CG2 3.49Å; I137-T143 VanDerWaalsContact CG2-CG2 3.49Å; I137-I145 HydrophobicContact CG2-CD1 4.08Å; I137-M177 HydrophobicContact CG2-CE 4.02Å; I137-M177 HydrophobicContact CG2-SD 4.2Å; I137-Q218 HydrophobicContact CD1-CB 3.95Å; I137-L219 HydrophobicContact CD1-CB 4.26Å; I137-L219 HydrophobicContact CG1-CD1 4.13Å; I137-F243 HydrophobicContact CD1-CD2 3.95Å; I137-F243 HydrophobicContact CD1-CE2 4.03Å
138S93.2Very high94.3Very high75 Ų7532.8 Ų32.852%0.52419%0.19SC..PPolyproline II helixtrans-74.4141.5-178.2-590000111.6T143 M177S138-T143 VanDerWaalsContact O-CB 3.31Å; S138-T143 WeakPolarHBondContact O-CB 3.23Å; S138-T143 WeakPolarHBondContact O-CG2 3.39Å; S138-T143 PolarHBondContact O-OG1 3.25Å; S138-M177 WeakPolarHBondContact O-CE 3.26Å
139P95Very high93.8Very high76 Ų7633 Ų3349%0.49419%0.191SC..PPolyproline II helixtrans-70.6159.9170.732.8-36.2000111.3L133 Y175L133-P139 HydrophobicContact CD2-CB 4.21Å; L133-P139 HydrophobicContact CD2-CG 4.44Å; P139-Y175 HydrophobicContact CB-CG 4.43Å
140G94.3Very high92.7Very high20 Ų2036.3 Ų36.321%0.20620%0.204CC..SBendtrans104.3178.6170.700000116.1D142 T143 Y175 S176G140-D142 VanDerWaalsContact C-N 3.26Å; G140-D142 PolarHBondContact O-N 3.25Å; G140-T143 WeakPolarHBondContact O-CB 3.46Å; G140-T143 PolarHBondContact O-N 2.65Å; G140-T143 VanDerWaalsContact O-N 3.11Å; G140-Y175 PolarHBondContact N-O 2.86Å; G140-S176 CarbonylContact C-O 3.46Å; G140-S176 WeakPolarHBondContact CA-O 3.2Å
141Q93.5Very high91.1Very high48 Ų4834 Ų3422%0.22419%0.194CC..THydrogen-bonded Turntrans-71.7-11.4-166.7-71.2-70.7-66.300115.5T143 S176 D291 L292Q141-T143 VanDerWaalsContact C-N 3.31Å; Q141-S176 PolarHBondContact N-O 2.8Å; Q141-S176 PolarHBondContact NE2-O 2.98Å; Q141-D291 HydrophobicContact CG-CB 4.22Å; Q141-L292 PolarHBondContact NE2-O 3.23Å
142D90.5Very high89.6Confident127 Ų12733.6 Ų33.668%0.67919%0.192SC*.THydrogen-bonded Turntrans-84.7-6.8173.5-65.6-40.6000112.7G140 F144G140-D142 VanDerWaalsContact C-N 3.26Å; G140-D142 PolarHBondContact O-N 3.25Å; D142-F144 WeakPolarHBondContact O-CD2 3.25Å
143T92.8Very high87.1Confident21 Ų2133.6 Ų33.613%0.12919%0.192CC..  trans-99.9120.6-177.9-65.40000111.5I137 S138 G140 Q141 I145 M177 V178I137-T143 HydrophobicContact CG2-CG2 3.49Å; I137-T143 VanDerWaalsContact CG2-CG2 3.49Å; S138-T143 VanDerWaalsContact O-CB 3.31Å; S138-T143 WeakPolarHBondContact O-CB 3.23Å; S138-T143 WeakPolarHBondContact O-CG2 3.39Å; S138-T143 PolarHBondContact O-OG1 3.25Å; G140-T143 WeakPolarHBondContact O-CB 3.46Å; G140-T143 PolarHBondContact O-N 2.65Å; G140-T143 VanDerWaalsContact O-N 3.11Å; Q141-T143 VanDerWaalsContact C-N 3.31Å; T143-I145 HydrophobicContact CG2-CD1 3.97Å; T143-I145 HydrophobicContact CG2-CG1 4.4Å; T143-M177 HydrophobicContact CG2-CB 4.24Å; T143-M177 HydrophobicContact CG2-CG 3.9Å; T143-M177 HydrophobicContact CG2-SD 3.9Å; T143-V178 PolarHBondContact O-N 2.87Å
144F92.8Very high84.4Confident17 Ų1734.5 Ų34.58%0.07520%0.196CC..EExtended strand (participates in β ladder)trans-112.6125.7-179.8-64-97.8000110.8D142 V178 V180 A215 I217 V295 Y541D142-F144 WeakPolarHBondContact O-CD2 3.25Å; F144-V178 CarbonylContact C-O 3.59Å; F144-V178 VanDerWaalsContact CA-O 3.31Å; F144-V178 WeakPolarHBondContact CA-O 3.33Å; F144-V178 HydrophobicContact CD1-CB 3.84Å; F144-V178 HydrophobicContact CD1-CG1 3.95Å; F144-V178 HydrophobicContact CE1-CB 3.92Å; F144-V178 HydrophobicContact CE1-CG1 3.88Å; F144-V178 HydrophobicContact CE1-CG2 4.23Å; F144-V178 HydrophobicContact CG-CB 4.49Å; F144-V180 HydrophobicContact CB-CG2 3.95Å; F144-V180 HydrophobicContact CD1-CG2 3.83Å; F144-V180 HydrophobicContact CG-CG2 4.38Å; F144-A215 HydrophobicContact CD2-CB 3.61Å; F144-A215 HydrophobicContact CE2-CB 3.52Å; F144-A215 HydrophobicContact CZ-CB 4.35Å; F144-I217 HydrophobicContact CB-CG1 4.21Å; F144-V295 HydrophobicContact CD1-CG2 4.24Å; F144-V295 HydrophobicContact CE1-CG2 3.77Å; F144-Y541 AromaticContact CE1-CE2 3.92Å; F144-Y541 HydrophobicContact CE1-CE2 3.92Å; F144-Y541 AromaticContact CZ-CE2 3.7Å; F144-Y541 HydrophobicContact CZ-CE2 3.7Å; F144-Y541 AromaticContact CZ-CZ 3.95Å
145I93.7Very high81.7Confident1 Ų129 Ų291%0.00517%0.171CC..EExtended strand (participates in β ladder)trans-112.5119.4-179-54.8-61.6000109.8I137 T143 T172 M177 V178 N179 V180 L219 I221I137-I145 HydrophobicContact CG2-CD1 4.08Å; T143-I145 HydrophobicContact CG2-CD1 3.97Å; T143-I145 HydrophobicContact CG2-CG1 4.4Å; I145-T172 HydrophobicContact CB-CG2 3.85Å; I145-T172 HydrophobicContact CG1-CG2 4.02Å; I145-T172 HydrophobicContact CG2-CG2 4.2Å; I145-M177 HydrophobicContact CD1-SD 4.37Å; I145-M177 HydrophobicContact CG1-CB 4.47Å; I145-M177 HydrophobicContact CG1-SD 4.21Å; I145-V178 PolarHBondContact N-O 2.96Å; I145-N179 CarbonylContact O-C 3.56Å; I145-N179 WeakPolarHBondContact O-CA 3.44Å; I145-V180 PolarHBondContact O-N 2.94Å; I145-L219 HydrophobicContact CD1-CB 4Å; I145-L219 HydrophobicContact CD1-CD2 4.43Å; I145-L219 HydrophobicContact CG2-CD2 3.7Å; I145-I221 HydrophobicContact CG2-CD1 4.3Å
146G92.7Very high78.6Confident0 Ų036.5 Ų36.50%021%0.208CC..EExtended strand (participates in β ladder)trans-76.7134.3177.700000111.8V180 L219 I220 I221G146-V180 WeakPolarHBondContact CA-O 3.22Å; G146-L219 PolarHBondContact N-O 2.91Å; G146-I220 CarbonylContact O-C 3.56Å; G146-I220 WeakPolarHBondContact O-CA 3.4Å; G146-I221 PolarHBondContact O-N 2.93Å
147I91.5Very high75.9Confident0 Ų036.1 Ų36.10%020%0.198CC..EExtended strand (participates in β ladder)trans-118.7101.1171.7-53.9176.8000108.4W165 E169 N179 V180 L182I147-W165 HydrophobicContact CG2-CD2 4.38Å; I147-W165 HydrophobicContact CG2-CG 4.18Å; I147-E169 HydrophobicContact CD1-CB 4.33Å; I147-N179 HydrophobicContact CD1-CB 3.82Å; I147-N179 HydrophobicContact CG1-CB 4.41Å; I147-V180 PolarHBondContact N-O 3.43Å; I147-L182 PolarHBondContact O-N 2.9Å
148Y88.8Confident73.3Confident13 Ų1341.9 Ų41.95%0.05123%0.233CC..EExtended strand (participates in β ladder)trans-106.673-178.4-166.3-167.4000112L182 V191 I221 C222 D223 K227Y148-L182 HydrophobicContact CD2-CB 3.76Å; Y148-L182 WeakPolarHBondContact CD2-O 3.38Å; Y148-L182 HydrophobicContact CG-CB 3.92Å; Y148-L182 HydrophobicContact CG-CD1 4.34Å; Y148-V191 HydrophobicContact CD1-CG1 4.36Å; Y148-V191 HydrophobicContact CE1-CG1 4.18Å; Y148-V191 HydrophobicContact CE1-CG2 4.25Å; Y148-I221 PolarHBondContact N-O 3.46Å; Y148-C222 WeakPolarHBondContact O-CA 3.08Å; Y148-D223 PolarHBondContact O-N 3.46Å; Y148-K227 HydrophobicContact CD1-CD 3.57Å; Y148-K227 HydrophobicContact CD1-CG 3.68Å; Y148-K227 HydrophobicContact CD2-CD 3.76Å; Y148-K227 HydrophobicContact CE1-CD 3.61Å; Y148-K227 HydrophobicContact CE1-CG 3.4Å; Y148-K227 HydrophobicContact CE2-CD 3.81Å; Y148-K227 HydrophobicContact CE2-CG 4.41Å; Y148-K227 HydrophobicContact CG-CD 3.65Å; Y148-K227 HydrophobicContact CG-CG 4.28Å; Y148-K227 VanDerWaalsContact O-CD 3.26Å; Y148-K227 WeakPolarHBondContact O-CD 3.26Å; Y148-K227 PolarHBondContact O-NZ 2.89Å
149S84.7Confident70.8Confident5 Ų544.2 Ų44.24%0.03523%0.234CC..  trans-142.8140.5-171.4178.10000111.3D223 M247S149-D223 WeakPolarHBondContact OG-CB 3.43Å; S149-M247 PolarHBondContact OG-SD 2.93Å
150R74.4Confident68.4Low69 Ų6946.7 Ų46.726%0.2624%0.244SC..  trans-67.4162.3166.667.7-172.7-179.2144.95.2110.1R152 E154 D223 G366R150-R152 HydrophobicContact CG-CB 4.03Å; R150-R152 HydrophobicContact CG-CG 4.37Å; R150-R152 PolarHBondContact O-N 2.76Å; R150-E154 IonicContact NH2-OE2 2.86Å; R150-E154 PolarHBondContact NH2-OE2 3.22Å; R150-D223 WeakPolarHBondContact CG-OD2 3.29Å; R150-D223 PolarHBondContact N-OD2 2.93Å; R150-D223 VanDerWaalsContact N-OD2 3.15Å; R150-G366 PolarHBondContact NH1-O 2.86Å
151N65.3Low66.1Low4 Ų446.8 Ų46.82%0.02124%0.24CC..SBendtrans-60119161.7-86.532.3000108S338 L340 L342 Y364N151-S338 PolarHBondContact ND2-OG 3.38Å; N151-L340 PolarHBondContact ND2-O 3.19Å; N151-L340 PolarHBondContact OD1-O 3.08Å; N151-L342 WeakPolarHBondContact ND2-CG 3.48Å; N151-L342 WeakPolarHBondContact OD1-CB 3.44Å; N151-L342 WeakPolarHBondContact OD1-CD1 3.4Å; N151-L342 WeakPolarHBondContact OD1-CG 3.48Å; N151-L342 PolarHBondContact OD1-N 3.44Å; N151-Y364 HydrophobicContact CB-CE1 4.03Å; N151-Y364 WeakPolarHBondContact O-CE1 3.39Å; N151-Y364 PolarHBondContact O-OH 3.2Å
152R64.3Low64Low5 Ų545 Ų452%0.01923%0.232CC..  trans-153.1154.7179.463.4-175.1-62162.27.7108.7R150 E154 L164 D223 D248R150-R152 HydrophobicContact CG-CB 4.03Å; R150-R152 HydrophobicContact CG-CG 4.37Å; R150-R152 PolarHBondContact O-N 2.76Å; R152-E154 PolarHBondContact NE-O 2.78Å; R152-E154 PolarHBondContact NH2-O 3.41Å; R152-L164 WeakPolarHBondContact O-CD2 3.32Å; R152-D223 PolarHBondContact NH1-O 3.21Å; R152-D248 IonicContact CZ-OD1 3.32Å; R152-D248 IonicContact CZ-OD2 2.66Å; R152-D248 IonicContact NH1-OD1 3.03Å; R152-D248 IonicContact NH1-OD2 3.8Å; R152-D248 PolarHBondContact NH1-OD2 2.69Å; R152-D248 IonicContact NH2-OD1 3.7Å; R152-D248 PolarHBondContact NH2-OD1 3.07Å; R152-D248 IonicContact NH2-OD2 3.71Å; R152-D248 PolarHBondContact NH2-OD2 3.05Å; R152-D248 VanDerWaalsContact NH2-OD2 3.12Å
153P45Very low62.3Low1 Ų138.9 Ų38.91%0.00620%0.199CC..  trans-11910.6159.743-36.7000114.6Y102 L164 Y363 Y364Y102-P153 VanDerWaalsContact CB-CG 3.46Å; Y102-P153 HydrophobicContact CG-CB 4.11Å; P153-L164 HydrophobicContact CB-CD2 3.66Å; P153-Y363 HydrophobicContact CB-CD2 4.23Å; P153-Y363 HydrophobicContact CB-CG 4.2Å; P153-Y363 HydrophobicContact CG-CG 4.49Å; P153-Y364 WeakPolarHBondContact CD-O 3.37Å
154E40.4Very low61.2Low52 Ų5238 Ų3824%0.24319%0.193CC..  trans-92.1119.9-171.9-68.6176.9144.900110.8R111 R150 R152R111-E154 IonicContact NH1-OE1 2.97Å; R150-E154 IonicContact NH2-OE2 2.86Å; R150-E154 PolarHBondContact NH2-OE2 3.22Å; R152-E154 PolarHBondContact NE-O 2.78Å; R152-E154 PolarHBondContact NH2-O 3.41Å
155V39.4Very low60.9Low13 Ų1337.1 Ų37.18%0.07919%0.19CC..  -130.2135.8126.9170.20000109.4C157 E163 M247 D248 P249V155-C157 HydrophobicContact CG1-CB 3.91Å; V155-C157 WeakPolarHBondContact CG1-SG 3.15Å; V155-C157 PolarHBondContact O-N 3.3Å; V155-E163 HydrophobicContact CB-CB 4.47Å; V155-E163 HydrophobicContact CB-CG 3.97Å; V155-E163 HydrophobicContact CG2-CB 4.13Å; V155-E163 HydrophobicContact CG2-CG 3.97Å; V155-E163 WeakPolarHBondContact CG2-OE2 3.26Å; V155-M247 HydrophobicContact CG2-CB 4.38Å; V155-D248 WeakPolarHBondContact CG2-OD1 3.37Å; V155-P249 HydrophobicContact CG1-CG 4.17Å
156M30.6Very low60.8Low173 Ų17337.1 Ų37.185%0.85219%0.19SC*.  trans-6963.4165.7-168.7178.378.800109.3
157C36.8Very low60.8Low34 Ų3437.1 Ų37.123%0.2319%0.19CC..  trans-95.8123.7174.1-95.20000107.7V155 F159V155-C157 HydrophobicContact CG1-CB 3.91Å; V155-C157 WeakPolarHBondContact CG1-SG 3.15Å; V155-C157 PolarHBondContact O-N 3.3Å; C157-F159 PolarHBondContact O-N 2.87Å
158T38.7Very low60.9Low125 Ų12537.1 Ų37.177%0.76719%0.19SC*.SBendtrans-62.59172.835.20000114.1
159F41.5Very low61.2Low125 Ų12536.6 Ų36.655%0.54819%0.188SC..SBendtrans-149.887.7-168.2-64-69.6000109.7C157 V161 R273C157-F159 PolarHBondContact O-N 2.87Å; F159-V161 PolarHBondContact O-N 3.5Å; F159-R273 PolarHBondContact O-NH2 3.08Å
160D45.4Very low61.7Low128 Ų12836.5 Ų36.568%0.68419%0.187SC*.SBendtrans16.120.3158.6-53.3-40.9000123K104K104-D160 IonicContact NZ-OD1 3.76Å
161V45.4Very low62.8Low21 Ų2133.2 Ų33.213%0.12717%0.174CC..  trans-118.1105.2173.2-170.40000107.5F159 V272 R273F159-V161 PolarHBondContact O-N 3.5Å; V161-V272 HydrophobicContact CG1-CB 4.12Å; V161-V272 HydrophobicContact CG1-CG1 3.77Å; V161-V272 HydrophobicContact CG1-CG2 4.38Å; V161-R273 HydrophobicContact CG2-CG 4.08Å
162D50.3Low64.2Low10 Ų1033 Ų335%0.05317%0.173CC..  trans-87.2128.9-177.6-57.7-68.5000110.9Y102 L116 L164 I167Y102-D162 HydrophobicContact CD1-CB 4.35Å; Y102-D162 HydrophobicContact CE1-CB 3.96Å; Y102-D162 WeakPolarHBondContact CE1-OD2 3.43Å; Y102-D162 WeakPolarHBondContact CE2-OD1 3.42Å; Y102-D162 PolarHBondContact OH-OD1 2.94Å; Y102-D162 PolarHBondContact OH-OD2 3.31Å; L116-D162 HydrophobicContact CD1-CB 4.12Å; L116-D162 WeakPolarHBondContact CD2-OD2 3.37Å; D162-L164 HydrophobicContact CB-CD1 4.48Å; D162-L164 PolarHBondContact O-N 2.9Å; D162-I167 WeakPolarHBondContact O-CD1 3.26Å
163E54.2Low65.8Low0 Ų032.8 Ų32.80%017%0.173CC..  trans-9093.8-166.1-51-172.2170.700110.6V155 M247 F268 D269V155-E163 HydrophobicContact CB-CB 4.47Å; V155-E163 HydrophobicContact CB-CG 3.97Å; V155-E163 HydrophobicContact CG2-CB 4.13Å; V155-E163 HydrophobicContact CG2-CG 3.97Å; V155-E163 WeakPolarHBondContact CG2-OE2 3.26Å; E163-M247 HydrophobicContact CB-CB 4.26Å; E163-M247 HydrophobicContact CB-CG 4.36Å; E163-M247 VanDerWaalsContact CD-O 3.31Å; E163-M247 WeakPolarHBondContact OE2-CA 3.42Å; E163-M247 WeakPolarHBondContact OE2-CB 3.47Å; E163-F268 HydrophobicContact CB-CD1 3.71Å; E163-F268 HydrophobicContact CB-CE1 3.93Å; E163-F268 HydrophobicContact CB-CG 4.38Å; E163-F268 HydrophobicContact CG-CD1 3.52Å; E163-F268 HydrophobicContact CG-CE1 4.08Å; E163-F268 HydrophobicContact CG-CG 4.32Å; E163-D269 PolarHBondContact OE1-N 3.16Å
164L68.6Low68.4Low1 Ų132.9 Ų32.91%0.00517%0.173CC..  trans-108.6140.4-170.9-67.4162000111.2L100 L116 R152 P153 D162 V166 I167 S168 Y363L100-L164 HydrophobicContact CB-CD1 3.7Å; L100-L164 HydrophobicContact CD1-CB 4.32Å; L100-L164 HydrophobicContact CD1-CD1 3.54Å; L100-L164 HydrophobicContact CD1-CG 4.47Å; L100-L164 HydrophobicContact CG-CD1 4.26Å; L116-L164 HydrophobicContact CD1-CD1 3.66Å; R152-L164 WeakPolarHBondContact O-CD2 3.32Å; P153-L164 HydrophobicContact CB-CD2 3.66Å; D162-L164 HydrophobicContact CB-CD1 4.48Å; D162-L164 PolarHBondContact O-N 2.9Å; L164-V166 PolarHBondContact O-N 2.96Å; L164-I167 HydrophobicContact CB-CD1 4.08Å; L164-I167 HydrophobicContact CB-CG1 4.18Å; L164-I167 HydrophobicContact CD1-CD1 4.35Å; L164-I167 WeakPolarHBondContact O-CB 3.35Å; L164-I167 PolarHBondContact O-N 2.91Å; L164-S168 PolarHBondContact O-N 3.28Å; L164-Y363 HydrophobicContact CD2-CD2 3.85Å; L164-Y363 HydrophobicContact CD2-CE2 3.82Å
165W86.1Confident71.1Confident0 Ų030.5 Ų30.50%016%0.162CC..Hα-helixtrans-51.1-40.2171.3-169.4107.3000111.2I147 I167 S168 E169 P181 L342 R348I147-W165 HydrophobicContact CG2-CD2 4.38Å; I147-W165 HydrophobicContact CG2-CG 4.18Å; W165-I167 PolarHBondContact O-N 3.32Å; W165-S168 VanDerWaalsContact O-CB 3.32Å; W165-S168 WeakPolarHBondContact O-CB 3.47Å; W165-S168 PolarHBondContact O-N 2.96Å; W165-E169 HydrophobicContact CE3-CB 3.97Å; W165-E169 HydrophobicContact CH2-CB 4.41Å; W165-E169 HydrophobicContact CH2-CG 4.34Å; W165-E169 HydrophobicContact CZ3-CB 3.71Å; W165-E169 VanDerWaalsContact CZ3-CD 3.43Å; W165-E169 HydrophobicContact CZ3-CG 3.87Å; W165-E169 PolarHBondContact O-N 3.26Å; W165-P181 HydrophobicContact CZ2-CB 3.98Å; W165-L342 HydrophobicContact CB-CD1 3.89Å; W165-L342 HydrophobicContact CD2-CB 3.55Å; W165-L342 HydrophobicContact CD2-CD1 3.76Å; W165-L342 HydrophobicContact CD2-CG 4.22Å; W165-L342 HydrophobicContact CE3-CB 3.69Å; W165-L342 HydrophobicContact CE3-CD1 3.58Å; W165-L342 HydrophobicContact CE3-CD2 4.3Å; W165-L342 HydrophobicContact CE3-CG 4.04Å; W165-L342 HydrophobicContact CG-CB 4.12Å; W165-L342 HydrophobicContact CG-CD1 3.91Å; W165-L342 HydrophobicContact CH2-CB 3.88Å; W165-L342 WeakPolarHBondContact CH2-O 3.49Å; W165-L342 HydrophobicContact CZ2-CB 3.73Å; W165-L342 WeakPolarHBondContact CZ2-O 3.31Å; W165-L342 HydrophobicContact CZ3-CB 3.84Å; W165-L342 HydrophobicContact CZ3-CD1 4.3Å; W165-L342 HydrophobicContact CZ3-CD2 4.19Å; W165-L342 HydrophobicContact CZ3-CG 4.32Å; W165-R348 HydrophobicContact CH2-CG 4.13Å; W165-R348 HydrophobicContact CZ3-CG 4.41Å
166V91.9Very high73.9Confident0 Ų030.4 Ų30.40%016%0.162CC..Hα-helixtrans-63.6-37.7177.2173.60000112.8L100 V121 L164 S168 E169 Q170 L342 E351 M355 Y363L100-V166 HydrophobicContact CD1-CB 3.81Å; L100-V166 HydrophobicContact CD1-CG1 3.85Å; L100-V166 HydrophobicContact CD1-CG2 4.42Å; V121-V166 HydrophobicContact CG1-CG1 4.46Å; L164-V166 PolarHBondContact O-N 2.96Å; V166-S168 VanDerWaalsContact C-N 3.29Å; V166-S168 PolarHBondContact O-N 2.85Å; V166-E169 PolarHBondContact O-N 2.9Å; V166-Q170 HydrophobicContact CG1-CG 3.93Å; V166-Q170 WeakPolarHBondContact O-CB 3.27Å; V166-Q170 WeakPolarHBondContact O-CG 3.47Å; V166-Q170 PolarHBondContact O-N 2.8Å; V166-L342 HydrophobicContact CG2-CD1 4.33Å; V166-E351 WeakPolarHBondContact CG2-OE2 3.26Å; V166-M355 HydrophobicContact CB-CE 4.45Å; V166-M355 HydrophobicContact CG1-CE 3.56Å; V166-M355 HydrophobicContact CG2-CE 3.98Å; V166-Y363 WeakPolarHBondContact CG2-OH 3.35Å
167I92.9Very high77Confident0 Ų022.2 Ų22.20%012%0.121CC..Hα-helixtrans-63.7-41.3176.3-69.1167.8000110L116 V121 L128 D162 L164 W165 A171 F268L116-I167 HydrophobicContact CD1-CD1 4.36Å; V121-I167 HydrophobicContact CG1-CG1 4.14Å; L128-I167 HydrophobicContact CD2-CG2 4.28Å; D162-I167 WeakPolarHBondContact O-CD1 3.26Å; L164-I167 HydrophobicContact CB-CD1 4.08Å; L164-I167 HydrophobicContact CB-CG1 4.18Å; L164-I167 HydrophobicContact CD1-CD1 4.35Å; L164-I167 WeakPolarHBondContact O-CB 3.35Å; L164-I167 PolarHBondContact O-N 2.91Å; W165-I167 PolarHBondContact O-N 3.32Å; I167-A171 WeakPolarHBondContact O-CB 3.31Å; I167-A171 PolarHBondContact O-N 3.49Å; I167-F268 HydrophobicContact CB-CZ 4.4Å; I167-F268 HydrophobicContact CG2-CE1 4.47Å; I167-F268 HydrophobicContact CG2-CZ 3.97Å
168S93.9Very high79.8Confident0 Ų020.6 Ų20.60%011%0.11CC..Hα-helixtrans-62-45.3175.6-58.30000111.6L164 W165 V166 T172 F268L164-S168 PolarHBondContact O-N 3.28Å; W165-S168 VanDerWaalsContact O-CB 3.32Å; W165-S168 WeakPolarHBondContact O-CB 3.47Å; W165-S168 PolarHBondContact O-N 2.96Å; V166-S168 VanDerWaalsContact C-N 3.29Å; V166-S168 PolarHBondContact O-N 2.85Å; S168-T172 PolarHBondContact O-N 2.71Å; S168-F268 WeakPolarHBondContact OG-CE2 3.38Å
169E94.4Very high82.4Confident3 Ų314.7 Ų14.71%0.0147%0.074CC..Hα-helixtrans-60.8-54.7176.7-175.6-166.4-149.500111.3I147 W165 V166 A171 T172 Y173 R348I147-E169 HydrophobicContact CD1-CB 4.33Å; W165-E169 HydrophobicContact CE3-CB 3.97Å; W165-E169 HydrophobicContact CH2-CB 4.41Å; W165-E169 HydrophobicContact CH2-CG 4.34Å; W165-E169 HydrophobicContact CZ3-CB 3.71Å; W165-E169 VanDerWaalsContact CZ3-CD 3.43Å; W165-E169 HydrophobicContact CZ3-CG 3.87Å; W165-E169 PolarHBondContact O-N 3.26Å; V166-E169 PolarHBondContact O-N 2.9Å; E169-A171 VanDerWaalsContact C-N 3.27Å; E169-A171 PolarHBondContact O-N 3.01Å; E169-T172 WeakPolarHBondContact O-CB 3.48Å; E169-T172 PolarHBondContact O-N 3.17Å; E169-T172 VanDerWaalsContact O-N 3.07Å; E169-T172 PolarHBondContact O-OG1 2.9Å; E169-Y173 VanDerWaalsContact CD-OH 3.32Å; E169-Y173 HydrophobicContact CG-CE2 3.65Å; E169-Y173 WeakPolarHBondContact CG-OH 3.43Å; E169-Y173 PolarHBondContact OE1-OH 3.21Å; E169-R348 IonicContact OE1-CZ 3.95Å; E169-R348 VanDerWaalsContact OE1-CZ 3.24Å; E169-R348 IonicContact OE1-NE 3.34Å; E169-R348 PolarHBondContact OE1-NE 2.88Å; E169-R348 IonicContact OE1-NH2 3.43Å; E169-R348 PolarHBondContact OE1-NH2 3.08Å
170Q96Very high84.9Confident3 Ų38.9 Ų8.91%0.0145%0.049CC..Hα-helixtrans-63.8-32.1-177.6-66.5-61-38.900112.4I87 S125 V166 T172 Y173 V174I87-Q170 HydrophobicContact CD1-CG 4.02Å; S125-Q170 WeakPolarHBondContact OG-CB 3.39Å; V166-Q170 HydrophobicContact CG1-CG 3.93Å; V166-Q170 WeakPolarHBondContact O-CB 3.27Å; V166-Q170 WeakPolarHBondContact O-CG 3.47Å; V166-Q170 PolarHBondContact O-N 2.8Å; Q170-T172 VanDerWaalsContact C-N 3.28Å; Q170-T172 PolarHBondContact O-N 3.1Å; Q170-Y173 PolarHBondContact O-N 2.83Å; Q170-V174 PolarHBondContact O-N 3.29Å
171A96.7Very high87Confident0 Ų02.8 Ų2.80%02%0.016CC..Hα-helixtrans-60.7-36.1174.300000112.5S125 L128 A129 F132 I167 E169 Y173 V174S125-A171 WeakPolarHBondContact O-CA 3.35Å; S125-A171 VanDerWaalsContact O-CB 3.25Å; S125-A171 WeakPolarHBondContact O-CB 3.47Å; L128-A171 HydrophobicContact CB-CB 3.89Å; L128-A171 HydrophobicContact CD2-CB 3.82Å; L128-A171 HydrophobicContact CG-CB 3.94Å; A129-A171 HydrophobicContact CB-CB 4.2Å; A129-A171 VanDerWaalsContact CB-O 3.27Å; A129-A171 WeakPolarHBondContact CB-O 3.05Å; F132-A171 HydrophobicContact CE2-CB 3.85Å; F132-A171 HydrophobicContact CZ-CB 4.23Å; I167-A171 WeakPolarHBondContact O-CB 3.31Å; I167-A171 PolarHBondContact O-N 3.49Å; E169-A171 VanDerWaalsContact C-N 3.27Å; E169-A171 PolarHBondContact O-N 3.01Å; A171-Y173 VanDerWaalsContact C-N 3.26Å; A171-Y173 PolarHBondContact O-N 2.84Å; A171-V174 PolarHBondContact O-N 3.1Å
172T96.6Very high88.8Confident0 Ų01.8 Ų1.80%01%0.01CC..Hα-helixtrans-62.4-35.917764.60000112I145 S168 E169 Q170 V174 M177 N179I145-T172 HydrophobicContact CB-CG2 3.85Å; I145-T172 HydrophobicContact CG1-CG2 4.02Å; I145-T172 HydrophobicContact CG2-CG2 4.2Å; S168-T172 PolarHBondContact O-N 2.71Å; E169-T172 WeakPolarHBondContact O-CB 3.48Å; E169-T172 PolarHBondContact O-N 3.17Å; E169-T172 VanDerWaalsContact O-N 3.07Å; E169-T172 PolarHBondContact O-OG1 2.9Å; Q170-T172 VanDerWaalsContact C-N 3.28Å; Q170-T172 PolarHBondContact O-N 3.1Å; T172-V174 PolarHBondContact O-N 2.71Å; T172-M177 WeakPolarHBondContact O-CA 3.5Å; T172-M177 WeakPolarHBondContact O-CB 3.21Å; T172-M177 PolarHBondContact O-N 3.39Å; T172-N179 HydrophobicContact CG2-CB 3.97Å; T172-N179 PolarHBondContact OG1-ND2 3.18Å
173Y97.9Very high90Very high0 Ų01.8 Ų1.80%01%0.009CC..Hα-helixtrans-75.4-21.7-177-50.2-36.3000113.7V83 E169 Q170 A171 Y175 S176 N179 P287 C293 H312 R348V83-Y173 HydrophobicContact CB-CE2 4.12Å; V83-Y173 HydrophobicContact CG1-CD2 4.35Å; V83-Y173 HydrophobicContact CG1-CE2 3.65Å; E169-Y173 VanDerWaalsContact CD-OH 3.32Å; E169-Y173 HydrophobicContact CG-CE2 3.65Å; E169-Y173 WeakPolarHBondContact CG-OH 3.43Å; E169-Y173 PolarHBondContact OE1-OH 3.21Å; Q170-Y173 PolarHBondContact O-N 2.83Å; A171-Y173 VanDerWaalsContact C-N 3.26Å; A171-Y173 PolarHBondContact O-N 2.84Å; Y173-Y175 PolarHBondContact O-N 3.05Å; Y173-Y175 VanDerWaalsContact O-N 3.13Å; Y173-S176 PolarHBondContact O-N 3.34Å; Y173-N179 WeakPolarHBondContact CE1-ND2 3.42Å; Y173-N179 VanDerWaalsContact CZ-ND2 3.3Å; Y173-N179 PolarHBondContact OH-ND2 3.11Å; Y173-P287 VanDerWaalsContact O-CD 3.25Å; Y173-P287 WeakPolarHBondContact O-CD 3.4Å; Y173-C293 WeakPolarHBondContact CE1-O 3.44Å; Y173-C293 VanDerWaalsContact CE1-SG 3.6Å; Y173-C293 PolarHBondContact OH-SG 3.02Å; Y173-H312 AromaticContact CD1-CE1 3.56Å; Y173-H312 AromaticContact CD1-NE2 3.84Å; Y173-H312 AromaticContact CE1-CE1 3.72Å; Y173-H312 AromaticContact CG-CE1 3.93Å; Y173-R348 PolarHBondContact OH-NH2 3.36Å; Y173-R348 VanDerWaalsContact OH-NH2 3.15Å
174V98.1Very high90.5Very high2 Ų25.3 Ų5.31%0.0123%0.028CC..THydrogen-bonded Turntrans-58.5-30.9-179177.10000112.5Y84 E126 A129 Q170 A171 T172 P284 T285Y84-V174 HydrophobicContact CE2-CG2 4.4Å; E126-V174 HydrophobicContact CG-CG1 4.31Å; E126-V174 HydrophobicContact CG-CG2 3.98Å; A129-V174 HydrophobicContact CB-CB 3.57Å; A129-V174 HydrophobicContact CB-CG1 3.86Å; A129-V174 HydrophobicContact CB-CG2 3.88Å; Q170-V174 PolarHBondContact O-N 3.29Å; A171-V174 PolarHBondContact O-N 3.1Å; T172-V174 PolarHBondContact O-N 2.71Å; V174-P284 HydrophobicContact CG1-CB 3.98Å; V174-P284 HydrophobicContact CG1-CG 4.2Å; V174-T285 CarbonylContact O-C 3.41Å; V174-T285 PolarHBondContact O-N 3.12Å
175Y97.9Very high90.4Very high3 Ų37.8 Ų7.81%0.0124%0.044CC..THydrogen-bonded Turntrans-126.932.9178.9-66-68.9000112.2A129 K130 L133 P139 G140 Y173 M177 P282 P283 T285A129-Y175 HydrophobicContact CB-CD2 3.89Å; A129-Y175 HydrophobicContact CB-CE2 3.95Å; K130-Y175 HydrophobicContact CG-CE2 4.49Å; L133-Y175 HydrophobicContact CD1-CD1 4.06Å; L133-Y175 HydrophobicContact CD1-CD2 3.84Å; L133-Y175 HydrophobicContact CD1-CE1 3.72Å; L133-Y175 HydrophobicContact CD1-CE2 3.5Å; L133-Y175 VanDerWaalsContact CD1-CE2 3.5Å; L133-Y175 HydrophobicContact CD1-CG 4.12Å; L133-Y175 VanDerWaalsContact CD1-CZ 3.43Å; L133-Y175 HydrophobicContact CD2-CD2 4.34Å; L133-Y175 HydrophobicContact CD2-CG 4.5Å; L133-Y175 HydrophobicContact CG-CD2 4.03Å; L133-Y175 HydrophobicContact CG-CE2 3.96Å; P139-Y175 HydrophobicContact CB-CG 4.43Å; G140-Y175 PolarHBondContact N-O 2.86Å; Y173-Y175 PolarHBondContact O-N 3.05Å; Y173-Y175 VanDerWaalsContact O-N 3.13Å; Y175-M177 PolarHBondContact O-N 3.29Å; Y175-M177 VanDerWaalsContact O-N 3.12Å; Y175-P282 HydrophobicContact CE1-CG 4.12Å; Y175-P282 PolarHBondContact OH-O 2.68Å; Y175-P283 WeakPolarHBondContact CE1-O 3.34Å; Y175-T285 CarbonylContact C-O 3.45Å; Y175-T285 WeakPolarHBondContact CA-O 3.43Å
176S97.6Very high89.3Confident11 Ų118.6 Ų8.68%0.0775%0.048CC..THydrogen-bonded Turntrans5432.8174.7-57.90000114.8G140 Q141 Y173 T285 P286 P287G140-S176 CarbonylContact C-O 3.46Å; G140-S176 WeakPolarHBondContact CA-O 3.2Å; Q141-S176 PolarHBondContact N-O 2.8Å; Q141-S176 PolarHBondContact NE2-O 2.98Å; Y173-S176 PolarHBondContact O-N 3.34Å; S176-T285 PolarHBondContact N-O 2.73Å; S176-T285 PolarHBondContact OG-O 2.88Å; S176-P286 PolarHBondContact OG-O 3.47Å; S176-P287 VanDerWaalsContact OG-CA 3.29Å; S176-P287 WeakPolarHBondContact OG-CA 3.37Å
177M96.2Very high88Confident1 Ų110.3 Ų10.31%0.0057%0.066CC..  trans-85160.1173-55174.1-17500110.2F132 L133 I137 S138 T143 I145 T172 Y175F132-M177 HydrophobicContact CB-CE 4.26Å; F132-M177 HydrophobicContact CD2-SD 4.08Å; L133-M177 HydrophobicContact CD2-CE 3.76Å; I137-M177 HydrophobicContact CG2-CE 4.02Å; I137-M177 HydrophobicContact CG2-SD 4.2Å; S138-M177 WeakPolarHBondContact O-CE 3.26Å; T143-M177 HydrophobicContact CG2-CB 4.24Å; T143-M177 HydrophobicContact CG2-CG 3.9Å; T143-M177 HydrophobicContact CG2-SD 3.9Å; I145-M177 HydrophobicContact CD1-SD 4.37Å; I145-M177 HydrophobicContact CG1-CB 4.47Å; I145-M177 HydrophobicContact CG1-SD 4.21Å; T172-M177 WeakPolarHBondContact O-CA 3.5Å; T172-M177 WeakPolarHBondContact O-CB 3.21Å; T172-M177 PolarHBondContact O-N 3.39Å; Y175-M177 PolarHBondContact O-N 3.29Å; Y175-M177 VanDerWaalsContact O-N 3.12Å
178V95.6Very high87Confident0 Ų012.9 Ų12.90%08%0.079CC..EExtended strand (participates in β ladder)trans-105.1127-177.3-171.20000110.1T143 F144 I145 L292 V295T143-V178 PolarHBondContact O-N 2.87Å; F144-V178 CarbonylContact C-O 3.59Å; F144-V178 VanDerWaalsContact CA-O 3.31Å; F144-V178 WeakPolarHBondContact CA-O 3.33Å; F144-V178 HydrophobicContact CD1-CB 3.84Å; F144-V178 HydrophobicContact CD1-CG1 3.95Å; F144-V178 HydrophobicContact CE1-CB 3.92Å; F144-V178 HydrophobicContact CE1-CG1 3.88Å; F144-V178 HydrophobicContact CE1-CG2 4.23Å; F144-V178 HydrophobicContact CG-CB 4.49Å; I145-V178 PolarHBondContact N-O 2.96Å; V178-L292 HydrophobicContact CG1-CB 4.02Å; V178-L292 HydrophobicContact CG2-CB 3.76Å; V178-V295 HydrophobicContact CG1-CG2 4.04Å
179N94.1Very high85.9Confident0 Ų021 Ų210%012%0.118CC..EExtended strand (participates in β ladder)trans-85.9143.3172.359.983.9000112.3I145 I147 T172 Y173 C293 T294 V295 R348I145-N179 CarbonylContact O-C 3.56Å; I145-N179 WeakPolarHBondContact O-CA 3.44Å; I147-N179 HydrophobicContact CD1-CB 3.82Å; I147-N179 HydrophobicContact CG1-CB 4.41Å; T172-N179 HydrophobicContact CG2-CB 3.97Å; T172-N179 PolarHBondContact OG1-ND2 3.18Å; Y173-N179 WeakPolarHBondContact CE1-ND2 3.42Å; Y173-N179 VanDerWaalsContact CZ-ND2 3.3Å; Y173-N179 PolarHBondContact OH-ND2 3.11Å; N179-C293 PolarHBondContact ND2-O 3.44Å; N179-T294 VanDerWaalsContact O-CA 3.28Å; N179-T294 WeakPolarHBondContact O-CA 3.46Å; N179-T294 PolarHBondContact O-OG1 3.48Å; N179-T294 WeakPolarHBondContact OD1-CB 3.45Å; N179-T294 PolarHBondContact OD1-OG1 2.67Å; N179-V295 PolarHBondContact O-N 3.04Å; N179-V295 VanDerWaalsContact O-N 3.08Å; N179-R348 PolarHBondContact OD1-NH2 3.18Å
180V93.4Very high84.9Confident3 Ų321.6 Ų21.62%0.01812%0.123CC..EExtended strand (participates in β ladder)trans-119.894.7176.5-175.80000108.4F144 I145 G146 I147 L182 I194 I217 V295 Y297F144-V180 HydrophobicContact CB-CG2 3.95Å; F144-V180 HydrophobicContact CD1-CG2 3.83Å; F144-V180 HydrophobicContact CG-CG2 4.38Å; I145-V180 PolarHBondContact O-N 2.94Å; G146-V180 WeakPolarHBondContact CA-O 3.22Å; I147-V180 PolarHBondContact N-O 3.43Å; V180-L182 HydrophobicContact CG1-CD2 4.36Å; V180-I194 HydrophobicContact CG1-CG2 3.87Å; V180-I217 HydrophobicContact CB-CD1 3.98Å; V180-I217 HydrophobicContact CG1-CD1 3.98Å; V180-I217 HydrophobicContact CG2-CD1 4.17Å; V180-V295 HydrophobicContact CG2-CB 4.34Å; V180-Y297 HydrophobicContact CG1-CD2 3.92Å; V180-Y297 HydrophobicContact CG1-CE2 3.61Å
181P89.3Confident84Confident1 Ų121.5 Ų21.51%0.00612%0.123CC..EExtended strand (participates in β ladder)trans-71.8134.6-18029-35.9000112W165 T294 V295 A343W165-P181 HydrophobicContact CZ2-CB 3.98Å; P181-T294 WeakPolarHBondContact CD-OG1 3.37Å; P181-V295 WeakPolarHBondContact CD-O 3.35Å; P181-A343 HydrophobicContact CB-CB 3.93Å
182L83.4Confident83.2Confident0 Ų022.1 Ų22.10%013%0.127CC..EExtended strand (participates in β ladder)trans-119.4123.8177.7-55173000108.3I147 Y148 V180 L186 V191 I194I147-L182 PolarHBondContact O-N 2.9Å; Y148-L182 HydrophobicContact CD2-CB 3.76Å; Y148-L182 WeakPolarHBondContact CD2-O 3.38Å; Y148-L182 HydrophobicContact CG-CB 3.92Å; Y148-L182 HydrophobicContact CG-CD1 4.34Å; V180-L182 HydrophobicContact CG1-CD2 4.36Å; L182-L186 HydrophobicContact CB-CD1 4.2Å; L182-L186 HydrophobicContact CD2-CD1 4.16Å; L182-V191 HydrophobicContact CD1-CG1 4.2Å; L182-I194 HydrophobicContact CD2-CB 4.11Å; L182-I194 HydrophobicContact CD2-CD1 3.79Å; L182-I194 HydrophobicContact CD2-CG2 3.65Å
183Y74.4Confident82.4Confident9 Ų924.4 Ų24.44%0.03514%0.136CC..  trans-100149.8178.846-83.5000112.6T185 L186 Y297 S299 A343 P694Y183-T185 WeakPolarHBondContact CD2-OG1 3.49Å; Y183-T185 PolarHBondContact O-N 3.43Å; Y183-T185 VanDerWaalsContact O-N 3.11Å; Y183-L186 HydrophobicContact CD1-CD1 3.98Å; Y183-L186 HydrophobicContact CD1-CG 3.99Å; Y183-L186 HydrophobicContact CD2-CB 4.32Å; Y183-L186 HydrophobicContact CD2-CD1 4.38Å; Y183-L186 HydrophobicContact CD2-CD2 4.37Å; Y183-L186 HydrophobicContact CD2-CG 3.63Å; Y183-L186 HydrophobicContact CE1-CD1 3.98Å; Y183-L186 HydrophobicContact CE1-CD2 3.82Å; Y183-L186 HydrophobicContact CE1-CG 3.76Å; Y183-L186 HydrophobicContact CE2-CB 4.2Å; Y183-L186 HydrophobicContact CE2-CD1 4.37Å; Y183-L186 HydrophobicContact CE2-CD2 3.6Å; Y183-L186 HydrophobicContact CE2-CG 3.36Å; Y183-L186 HydrophobicContact CG-CD1 4.19Å; Y183-L186 HydrophobicContact CG-CG 3.93Å; Y183-L186 VanDerWaalsContact CZ-CG 3.45Å; Y183-L186 WeakPolarHBondContact O-CB 3.47Å; Y183-L186 PolarHBondContact O-N 3.14Å; Y183-L186 VanDerWaalsContact O-N 3.09Å; Y183-L186 VanDerWaalsContact OH-CD2 3.24Å; Y183-L186 WeakPolarHBondContact OH-CD2 3.3Å; Y183-Y297 VanDerWaalsContact CE1-O 3.31Å; Y183-Y297 WeakPolarHBondContact CE1-O 3.43Å; Y183-Y297 PolarHBondContact OH-O 2.95Å; Y183-Y297 VanDerWaalsContact OH-O 3.13Å; Y183-S299 WeakPolarHBondContact OH-CA 3.32Å; Y183-S299 PolarHBondContact OH-N 3.04Å; Y183-A343 HydrophobicContact CD1-CB 3.88Å; Y183-A343 HydrophobicContact CG-CB 4.28Å; Y183-P694 HydrophobicContact CD2-CB 4Å; Y183-P694 HydrophobicContact CE2-CB 3.38Å; Y183-P694 HydrophobicContact CE2-CG 4.09Å
184D66.5Low81.5Confident74 Ų7424.6 Ų24.640%0.39614%0.137SC..G310 helixtrans-54.7-34.1-174-71.3-7.7000114.2K227D184-K227 WeakPolarHBondContact OD1-CE 3.38Å; D184-K227 IonicContact OD1-NZ 3.4Å; D184-K227 PolarHBondContact OD1-NZ 2.85Å; D184-K227 IonicContact OD2-NZ 2.77Å
185T65.2Low80.7Confident54 Ų5424.5 Ų24.533%0.33114%0.136SC..G310 helixtrans-85.1-4.6-174.452.30000113.6Y183 G187 P694Y183-T185 WeakPolarHBondContact CD2-OG1 3.49Å; Y183-T185 PolarHBondContact O-N 3.43Å; Y183-T185 VanDerWaalsContact O-N 3.11Å; T185-G187 PolarHBondContact O-N 3.06Å; T185-P694 WeakPolarHBondContact CB-O 3.32Å; T185-P694 VanDerWaalsContact O-CB 3.26Å; T185-P694 WeakPolarHBondContact O-CB 3.24Å; T185-P694 WeakPolarHBondContact O-CG 3.29Å; T185-P694 WeakPolarHBondContact OG1-CA 3.49Å; T185-P694 VanDerWaalsContact OG1-CB 3.24Å; T185-P694 WeakPolarHBondContact OG1-CB 3.49Å; T185-P694 PolarHBondContact OG1-O 2.9Å
186L64.1Low79.7Confident16 Ų1627.3 Ų27.38%0.08415%0.149CC..G310 helixtrans-53.1-35177-87.8164.7000112.9L182 Y183 A190 V191 I194 P305L182-L186 HydrophobicContact CB-CD1 4.2Å; L182-L186 HydrophobicContact CD2-CD1 4.16Å; Y183-L186 HydrophobicContact CD1-CD1 3.98Å; Y183-L186 HydrophobicContact CD1-CG 3.99Å; Y183-L186 HydrophobicContact CD2-CB 4.32Å; Y183-L186 HydrophobicContact CD2-CD1 4.38Å; Y183-L186 HydrophobicContact CD2-CD2 4.37Å; Y183-L186 HydrophobicContact CD2-CG 3.63Å; Y183-L186 HydrophobicContact CE1-CD1 3.98Å; Y183-L186 HydrophobicContact CE1-CD2 3.82Å; Y183-L186 HydrophobicContact CE1-CG 3.76Å; Y183-L186 HydrophobicContact CE2-CB 4.2Å; Y183-L186 HydrophobicContact CE2-CD1 4.37Å; Y183-L186 HydrophobicContact CE2-CD2 3.6Å; Y183-L186 HydrophobicContact CE2-CG 3.36Å; Y183-L186 HydrophobicContact CG-CD1 4.19Å; Y183-L186 HydrophobicContact CG-CG 3.93Å; Y183-L186 VanDerWaalsContact CZ-CG 3.45Å; Y183-L186 WeakPolarHBondContact O-CB 3.47Å; Y183-L186 PolarHBondContact O-N 3.14Å; Y183-L186 VanDerWaalsContact O-N 3.09Å; Y183-L186 VanDerWaalsContact OH-CD2 3.24Å; Y183-L186 WeakPolarHBondContact OH-CD2 3.3Å; L186-A190 HydrophobicContact CB-CB 4.14Å; L186-A190 HydrophobicContact CD2-CB 4.16Å; L186-A190 VanDerWaalsContact O-CB 3.24Å; L186-A190 WeakPolarHBondContact O-CB 3.22Å; L186-V191 HydrophobicContact CB-CG2 3.96Å; L186-V191 HydrophobicContact CD1-CG2 4.15Å; L186-I194 HydrophobicContact CD1-CD1 3.87Å; L186-I194 HydrophobicContact CD2-CD1 4.15Å; L186-P305 HydrophobicContact CD2-CG 4.49Å
187G64.9Low78.1Confident37 Ų3727.1 Ų27.138%0.38115%0.147SC..  trans83.8148.6-167.700000112.1T185 E189 A190 V191T185-G187 PolarHBondContact O-N 3.06Å; G187-E189 VanDerWaalsContact C-N 3.32Å; G187-E189 PolarHBondContact O-N 2.87Å; G187-A190 PolarHBondContact O-N 3.13Å; G187-V191 WeakPolarHBondContact O-CG2 3.09Å; G187-V191 PolarHBondContact O-N 3.25Å; G187-V191 VanDerWaalsContact O-N 3.1Å
188N71.8Confident75.6Confident53 Ų5329.7 Ų29.728%0.28317%0.165SC..Hα-helixtrans-62.4-37.5-171.6-59.8-45000112.7A190 V191 C192 H234N188-A190 PolarHBondContact O-N 3.44Å; N188-V191 PolarHBondContact O-N 2.97Å; N188-C192 WeakPolarHBondContact O-CB 3.24Å; N188-C192 PolarHBondContact O-N 2.93Å; N188-C192 PolarHBondContact O-SG 3.43Å; N188-H234 HydrophobicContact CB-CB 4.26Å; N188-H234 VanDerWaalsContact CG-CE1 3.5Å; N188-H234 PolarHBondContact ND2-CE1 3.02Å; N188-H234 PolarHBondContact ND2-NE2 3.44Å; N188-H234 VanDerWaalsContact ND2-NE2 3.19Å
189E70.1Confident72.7Confident172 Ų17233.7 Ų33.780%0.80419%0.186SC*.Hα-helixtrans-61.8-42.4178.1-66.4-179.3178.100112.2G187 C192 Y193G187-E189 VanDerWaalsContact C-N 3.32Å; G187-E189 PolarHBondContact O-N 2.87Å; E189-C192 PolarHBondContact O-N 3.28Å; E189-Y193 WeakPolarHBondContact O-CB 3.43Å; E189-Y193 PolarHBondContact O-N 2.87Å
190A73.6Confident69.6Low15 Ų1538.7 Ų38.712%0.12422%0.216CC..Hα-helixtrans-66.6-41176.700000111.4L186 G187 N188 Y193 I194 P305L186-A190 HydrophobicContact CB-CB 4.14Å; L186-A190 HydrophobicContact CD2-CB 4.16Å; L186-A190 VanDerWaalsContact O-CB 3.24Å; L186-A190 WeakPolarHBondContact O-CB 3.22Å; G187-A190 PolarHBondContact O-N 3.13Å; N188-A190 PolarHBondContact O-N 3.44Å; A190-Y193 WeakPolarHBondContact O-CB 3.49Å; A190-Y193 PolarHBondContact O-N 3.08Å; A190-I194 WeakPolarHBondContact O-CD1 3.4Å; A190-I194 VanDerWaalsContact O-CG1 3.22Å; A190-I194 WeakPolarHBondContact O-CG1 3.47Å; A190-I194 PolarHBondContact O-N 3.03Å; A190-P305 HydrophobicContact CB-CG 3.85Å
191V77.9Confident66.5Low1 Ų143.9 Ų43.91%0.00624%0.244CC..Hα-helixtrans-61.2-48.7175171.10000110.7Y148 L182 L186 G187 N188 Y193 I194 I195 L231Y148-V191 HydrophobicContact CD1-CG1 4.36Å; Y148-V191 HydrophobicContact CE1-CG1 4.18Å; Y148-V191 HydrophobicContact CE1-CG2 4.25Å; L182-V191 HydrophobicContact CD1-CG1 4.2Å; L186-V191 HydrophobicContact CB-CG2 3.96Å; L186-V191 HydrophobicContact CD1-CG2 4.15Å; G187-V191 WeakPolarHBondContact O-CG2 3.09Å; G187-V191 PolarHBondContact O-N 3.25Å; G187-V191 VanDerWaalsContact O-N 3.1Å; N188-V191 PolarHBondContact O-N 2.97Å; V191-Y193 VanDerWaalsContact C-N 3.31Å; V191-Y193 PolarHBondContact O-N 3.12Å; V191-I194 PolarHBondContact O-N 2.71Å; V191-I195 HydrophobicContact CG1-CD1 3.68Å; V191-I195 HydrophobicContact CG1-CG1 4.5Å; V191-I195 WeakPolarHBondContact O-CD1 3.37Å; V191-I195 VanDerWaalsContact O-CG1 3.26Å; V191-I195 WeakPolarHBondContact O-CG1 3.29Å; V191-I195 PolarHBondContact O-N 2.9Å; V191-L231 HydrophobicContact CG1-CD1 3.73Å
192C79.3Confident63.6Low13 Ų1353.2 Ų53.29%0.08829%0.285CS..Hα-helixtrans-60.5-41.3175.8-69.10000111.7N188 E189 I194 I195 H196 H234 L235N188-C192 WeakPolarHBondContact O-CB 3.24Å; N188-C192 PolarHBondContact O-N 2.93Å; N188-C192 PolarHBondContact O-SG 3.43Å; E189-C192 PolarHBondContact O-N 3.28Å; C192-I194 PolarHBondContact O-N 2.85Å; C192-I195 PolarHBondContact O-N 2.86Å; C192-H196 WeakPolarHBondContact O-CB 3.45Å; C192-H196 VanDerWaalsContact O-CG 3.23Å; C192-H196 PolarHBondContact O-N 2.95Å; C192-H196 PolarHBondContact O-ND1 3.27Å; C192-H234 VanDerWaalsContact SG-CB 3.51Å; C192-L235 HydrophobicContact CB-CD2 4.21Å
193Y78.7Confident61.1Low48 Ų4859 Ų5919%0.18831%0.314CS..Hα-helixtrans-58.5-45.8174.8169.3-101.7000112.2E189 A190 V191 H196 Q197 R304 P305E189-Y193 WeakPolarHBondContact O-CB 3.43Å; E189-Y193 PolarHBondContact O-N 2.87Å; A190-Y193 WeakPolarHBondContact O-CB 3.49Å; A190-Y193 PolarHBondContact O-N 3.08Å; V191-Y193 VanDerWaalsContact C-N 3.31Å; V191-Y193 PolarHBondContact O-N 3.12Å; Y193-H196 CarbonylContact O-C 3.51Å; Y193-H196 PolarHBondContact O-N 2.84Å; Y193-Q197 HydrophobicContact CE2-CG 4.42Å; Y193-Q197 WeakPolarHBondContact O-CA 3.24Å; Y193-Q197 PolarHBondContact O-N 3.11Å; Y193-Q197 PolarHBondContact OH-NE2 2.56Å; Y193-Q197 VanDerWaalsContact OH-NE2 3.16Å; Y193-R304 HydrophobicContact CE1-CB 4.08Å; Y193-P305 HydrophobicContact CD1-CG 4.48Å; Y193-P305 WeakPolarHBondContact CE1-O 3.4Å
194I80.1Confident59Low4 Ų463.6 Ų63.62%0.02135%0.347CS..Hα-helixtrans-64.2-44.2-179.9-67.5162.9000111V180 L182 L186 A190 V191 C192 H196 Q197 I217 Y297 P305V180-I194 HydrophobicContact CG1-CG2 3.87Å; L182-I194 HydrophobicContact CD2-CB 4.11Å; L182-I194 HydrophobicContact CD2-CD1 3.79Å; L182-I194 HydrophobicContact CD2-CG2 3.65Å; L186-I194 HydrophobicContact CD1-CD1 3.87Å; L186-I194 HydrophobicContact CD2-CD1 4.15Å; A190-I194 WeakPolarHBondContact O-CD1 3.4Å; A190-I194 VanDerWaalsContact O-CG1 3.22Å; A190-I194 WeakPolarHBondContact O-CG1 3.47Å; A190-I194 PolarHBondContact O-N 3.03Å; V191-I194 PolarHBondContact O-N 2.71Å; C192-I194 PolarHBondContact O-N 2.85Å; I194-H196 VanDerWaalsContact C-N 3.3Å; I194-H196 PolarHBondContact O-N 3.47Å; I194-Q197 PolarHBondContact O-N 3.45Å; I194-I217 HydrophobicContact CG2-CD1 4.27Å; I194-Y297 HydrophobicContact CB-CE1 4.48Å; I194-Y297 HydrophobicContact CB-CE2 4.39Å; I194-Y297 HydrophobicContact CD1-CD1 3.96Å; I194-Y297 HydrophobicContact CD1-CD2 4.01Å; I194-Y297 HydrophobicContact CD1-CG 3.62Å; I194-Y297 HydrophobicContact CG1-CD1 3.63Å; I194-Y297 HydrophobicContact CG1-CD2 4.05Å; I194-Y297 HydrophobicContact CG1-CE1 3.78Å; I194-Y297 HydrophobicContact CG1-CE2 4.21Å; I194-Y297 HydrophobicContact CG1-CG 3.75Å; I194-Y297 HydrophobicContact CG2-CD2 3.76Å; I194-Y297 HydrophobicContact CG2-CE1 4.28Å; I194-Y297 HydrophobicContact CG2-CE2 3.39Å; I194-Y297 HydrophobicContact CG2-CG 4.34Å; I194-P305 HydrophobicContact CD1-CB 4.48Å
195I80.5Confident57.3Low0 Ų067.7 Ų67.70%037%0.368CS..Hα-helixtrans-63.3-41.2177.8-64.8163.8000110.7V191 C192 I220 L231 L235V191-I195 HydrophobicContact CG1-CD1 3.68Å; V191-I195 HydrophobicContact CG1-CG1 4.5Å; V191-I195 WeakPolarHBondContact O-CD1 3.37Å; V191-I195 VanDerWaalsContact O-CG1 3.26Å; V191-I195 WeakPolarHBondContact O-CG1 3.29Å; V191-I195 PolarHBondContact O-N 2.9Å; C192-I195 PolarHBondContact O-N 2.86Å; I195-I220 HydrophobicContact CD1-CD1 3.32Å; I195-I220 HydrophobicContact CG1-CD1 3.65Å; I195-I220 HydrophobicContact CG2-CD1 4.47Å; I195-L231 HydrophobicContact CD1-CD1 3.56Å; I195-L231 HydrophobicContact CD1-CD2 4.36Å; I195-L235 HydrophobicContact CB-CD2 4.28Å; I195-L235 HydrophobicContact CD1-CD1 4.34Å; I195-L235 HydrophobicContact CD1-CD2 3.99Å; I195-L235 HydrophobicContact CG2-CD2 4.04Å
196H76.4Confident55.8Low61 Ų6173.4 Ų73.428%0.28239%0.391SS..THydrogen-bonded Turntrans-89.27-177.5-67.4148000114.4C192 Y193 I194 S198 T238C192-H196 WeakPolarHBondContact O-CB 3.45Å; C192-H196 VanDerWaalsContact O-CG 3.23Å; C192-H196 PolarHBondContact O-N 2.95Å; C192-H196 PolarHBondContact O-ND1 3.27Å; Y193-H196 CarbonylContact O-C 3.51Å; Y193-H196 PolarHBondContact O-N 2.84Å; I194-H196 VanDerWaalsContact C-N 3.3Å; I194-H196 PolarHBondContact O-N 3.47Å; H196-S198 PolarHBondContact O-N 3.47Å; H196-S198 PolarHBondContact O-OG 2.96Å; H196-T238 VanDerWaalsContact NE2-CG2 3.34Å; H196-T238 WeakPolarHBondContact NE2-CG2 3.5Å
197Q65.5Low54.5Low8 Ų879 Ų794%0.03743%0.43CS..  trans-65.373.5-172.5-158.6-175.412.600111.8Y193 I194 Y297 K542Y193-Q197 HydrophobicContact CE2-CG 4.42Å; Y193-Q197 WeakPolarHBondContact O-CA 3.24Å; Y193-Q197 PolarHBondContact O-N 3.11Å; Y193-Q197 PolarHBondContact OH-NE2 2.56Å; Y193-Q197 VanDerWaalsContact OH-NE2 3.16Å; I194-Q197 PolarHBondContact O-N 3.45Å; Q197-Y297 PolarHBondContact OE1-OH 2.88Å; Q197-K542 PolarHBondContact O-NZ 3.49Å
198S43.7Very low53Low54 Ų5480.6 Ų80.638%0.37845%0.446SS..  trans-84.2117.4160.451.40000103.4H196 T200H196-S198 PolarHBondContact O-N 3.47Å; H196-S198 PolarHBondContact O-OG 2.96Å; S198-T200 PolarHBondContact O-N 3.01Å
199L34.5Very low51.2Low85 Ų8583.7 Ų83.745%0.44547%0.472SS..  trans-65.393.8162.2-90.8165.8000106L201 K542L199-L201 HydrophobicContact CD2-CD1 4.13Å; L199-L201 PolarHBondContact O-N 3.33Å; L199-K542 HydrophobicContact CD1-CB 3.43Å; L199-K542 VanDerWaalsContact CD1-CB 3.43Å; L199-K542 HydrophobicContact CD1-CD 3.84Å; L199-K542 HydrophobicContact CD1-CG 3.62Å; L199-K542 HydrophobicContact CG-CB 3.8Å; L199-K542 HydrophobicContact CG-CD 3.95Å; L199-K542 HydrophobicContact CG-CG 4.18Å
200T28.7Very low49.3Very low104 Ų10479.6 Ų79.664%0.63846%0.46SS*.  trans-73.473.2154.2-39.40000106.4S198 F202S198-T200 PolarHBondContact O-N 3.01Å; T200-F202 VanDerWaalsContact C-N 3.3Å; T200-F202 HydrophobicContact CG2-CD2 4.1Å; T200-F202 HydrophobicContact CG2-CE2 4.04Å; T200-F202 PolarHBondContact O-N 3.34Å
201L28.5Very low47.1Very low113 Ų11385.8 Ų85.859%0.59249%0.491SS*.  trans-68.5100168.3-150.671.8000104.9L199 I203L199-L201 HydrophobicContact CD2-CD1 4.13Å; L199-L201 PolarHBondContact O-N 3.33Å; L201-I203 HydrophobicContact CB-CG1 4.2Å; L201-I203 HydrophobicContact CD2-CD1 3.24Å; L201-I203 HydrophobicContact CD2-CG1 3.36Å; L201-I203 HydrophobicContact CG-CD1 4.02Å; L201-I203 HydrophobicContact CG-CG1 3.52Å; L201-I203 PolarHBondContact O-N 2.6Å
202F27.8Very low44.7Very low197 Ų19795 Ų9586%0.86453%0.527SS*.  trans-64.663.6161.1-88.7-91.4000107.9T200 S204T200-F202 VanDerWaalsContact C-N 3.3Å; T200-F202 HydrophobicContact CG2-CD2 4.1Å; T200-F202 HydrophobicContact CG2-CE2 4.04Å; T200-F202 PolarHBondContact O-N 3.34Å; F202-S204 VanDerWaalsContact C-N 3.34Å; F202-S204 PolarHBondContact O-N 2.83Å; F202-S204 VanDerWaalsContact O-N 3.08Å
203I30Very low42.3Very low122 Ų122101 Ų10163%0.62655%0.552SS**  trans-73103.6161.2-63.1-167.5000104.9L201 I205L201-I203 HydrophobicContact CB-CG1 4.2Å; L201-I203 HydrophobicContact CD2-CD1 3.24Å; L201-I203 HydrophobicContact CD2-CG1 3.36Å; L201-I203 HydrophobicContact CG-CD1 4.02Å; L201-I203 HydrophobicContact CG-CG1 3.52Å; L201-I203 PolarHBondContact O-N 2.6Å; I203-I205 PolarHBondContact O-N 3.08Å
204S31.8Very low40.4Very low104 Ų104101.6 Ų101.673%0.72756%0.562SS**  trans-37.4114.6159.5174.80000109.5F202 Q206F202-S204 VanDerWaalsContact C-N 3.34Å; F202-S204 PolarHBondContact O-N 2.83Å; F202-S204 VanDerWaalsContact O-N 3.08Å; S204-Q206 PolarHBondContact O-N 2.85Å; S204-Q206 VanDerWaalsContact O-N 3.08Å
205I30.8Very low38.8Very low161 Ų161102.2 Ų102.283%0.82657%0.569SS**SBendtrans-29.9107.1174.8-58.6163.3000111.6I203I203-I205 PolarHBondContact O-N 3.08Å
206Q34.3Very low38.4Very low173 Ų173104.3 Ų104.381%0.80858%0.578SS**  trans-161.5111.2149-116.1159.9-15.200110.8S204S204-Q206 PolarHBondContact O-N 2.85Å; S204-Q206 VanDerWaalsContact O-N 3.08Å
207C34.9Very low38.8Very low134 Ų134101.7 Ų101.791%0.90557%0.566SS**SBendtrans66.5104.2167.6-66.10000117.9
208G33.9Very low40Very low71 Ų71104.8 Ų104.873%0.73258%0.581SS**SBendtrans110.3127.3161.500000113.2
209S33.5Very low42.4Very low117 Ų117102.2 Ų102.282%0.81856%0.563SS**  trans-50123177.9-410000110.7L211S209-L211 PolarHBondContact O-N 2.76Å; S209-L211 VanDerWaalsContact O-N 3.12Å
210P31.7Very low45.1Very low87 Ų8798.1 Ų98.157%0.56554%0.541SS*.  trans-62.8118.1174.3-14.426.5000108.5Y212P210-Y212 HydrophobicContact CB-CD2 4.42Å; P210-Y212 HydrophobicContact CB-CE1 4.34Å; P210-Y212 HydrophobicContact CB-CE2 4Å; P210-Y212 HydrophobicContact CG-CE2 4.34Å; P210-Y212 WeakPolarHBondContact O-CD2 2.88Å; P210-Y212 WeakPolarHBondContact O-CE2 3.43Å; P210-Y212 PolarHBondContact O-N 2.82Å; P210-Y212 VanDerWaalsContact O-N 3.09Å
211L26.7Very low48.2Very low145 Ų14593.2 Ų93.276%0.75951%0.511SS*.  trans-77.393.6170.5-162.265.7000106.6S209 F213S209-L211 PolarHBondContact O-N 2.76Å; S209-L211 VanDerWaalsContact O-N 3.12Å; L211-F213 HydrophobicContact CD2-CD2 4.24Å; L211-F213 HydrophobicContact CD2-CE2 3.55Å; L211-F213 HydrophobicContact CD2-CZ 4.5Å; L211-F213 HydrophobicContact CG-CD2 4.1Å; L211-F213 HydrophobicContact CG-CE2 3.78Å; L211-F213 PolarHBondContact O-N 3.37Å; L211-F213 VanDerWaalsContact O-N 3.08Å
212Y26.9Very low51.1Low194 Ų19487.8 Ų87.876%0.76148%0.483SS*.  trans-67.9102.3179.1-62.2-87.1000109.5P210P210-Y212 HydrophobicContact CB-CD2 4.42Å; P210-Y212 HydrophobicContact CB-CE1 4.34Å; P210-Y212 HydrophobicContact CB-CE2 4Å; P210-Y212 HydrophobicContact CG-CE2 4.34Å; P210-Y212 WeakPolarHBondContact O-CD2 2.88Å; P210-Y212 WeakPolarHBondContact O-CE2 3.43Å; P210-Y212 PolarHBondContact O-N 2.82Å; P210-Y212 VanDerWaalsContact O-N 3.09Å
213F29.3Very low54Low140 Ų14078.6 Ų78.661%0.61444%0.442SS*.  trans-95.786163.2-85.5-86.8000108.4L211 A215 K542L211-F213 HydrophobicContact CD2-CD2 4.24Å; L211-F213 HydrophobicContact CD2-CE2 3.55Å; L211-F213 HydrophobicContact CD2-CZ 4.5Å; L211-F213 HydrophobicContact CG-CD2 4.1Å; L211-F213 HydrophobicContact CG-CE2 3.78Å; L211-F213 PolarHBondContact O-N 3.37Å; L211-F213 VanDerWaalsContact O-N 3.08Å; F213-A215 PolarHBondContact O-N 3.28Å; F213-K542 PolarHBondContact O-NZ 3.38Å
214S38.7Very low56.8Low59 Ų5974.4 Ų74.441%0.41342%0.423SS..  trans-82.787.8170.171.70000108.7E216S214-E216 VanDerWaalsContact CB-OE1 3.29Å; S214-E216 WeakPolarHBondContact CB-OE1 3.19Å; S214-E216 WeakPolarHBondContact CB-OE2 3.28Å; S214-E216 PolarHBondContact O-N 3.19Å; S214-E216 PolarHBondContact OG-OE1 3.17Å; S214-E216 PolarHBondContact OG-OE2 2.95Å
215A46.3Very low59.7Low18 Ų1870.9 Ų70.915%0.14940%0.397CS..  trans-66.49315900000108F144 F213 Y541F144-A215 HydrophobicContact CD2-CB 3.61Å; F144-A215 HydrophobicContact CE2-CB 3.52Å; F144-A215 HydrophobicContact CZ-CB 4.35Å; F213-A215 PolarHBondContact O-N 3.28Å; A215-Y541 HydrophobicContact CB-CE1 4.39Å; A215-Y541 WeakPolarHBondContact CB-OH 3.34Å
216E72.2Confident62.5Low44 Ų4470.8 Ų70.821%0.20639%0.391CS..  trans-109.2125.1-177.7-78.1167.1163.400106.9S214 Q218 N240S214-E216 VanDerWaalsContact CB-OE1 3.29Å; S214-E216 WeakPolarHBondContact CB-OE1 3.19Å; S214-E216 WeakPolarHBondContact CB-OE2 3.28Å; S214-E216 PolarHBondContact O-N 3.19Å; S214-E216 PolarHBondContact OG-OE1 3.17Å; S214-E216 PolarHBondContact OG-OE2 2.95Å; E216-Q218 PolarHBondContact O-N 2.96Å; E216-N240 HydrophobicContact CB-CB 3.96Å; E216-N240 HydrophobicContact CG-CB 4.21Å; E216-N240 VanDerWaalsContact CG-ND2 3.27Å; E216-N240 WeakPolarHBondContact CG-ND2 3.42Å; E216-N240 PolarHBondContact OE1-ND2 2.99Å; E216-N240 PolarHBondContact OE1-OD1 2.88Å; E216-N240 PolarHBondContact OE2-OD1 2.61Å; E216-N240 VanDerWaalsContact OE2-OD1 3.09Å
217I85.8Confident65.1Low6 Ų663.4 Ų63.43%0.03136%0.356CS..  trans-65.6103.1177.5-62.1179.5000107.5F144 V180 I194 L219 I220F144-I217 HydrophobicContact CB-CG1 4.21Å; V180-I217 HydrophobicContact CB-CD1 3.98Å; V180-I217 HydrophobicContact CG1-CD1 3.98Å; V180-I217 HydrophobicContact CG2-CD1 4.17Å; I194-I217 HydrophobicContact CG2-CD1 4.27Å; I217-L219 WeakPolarHBondContact CG2-O 3.34Å; I217-I220 HydrophobicContact CG2-CD1 4.33Å; I217-I220 HydrophobicContact CG2-CG1 3.6Å
218Q89.7Confident67.8Low72 Ų7257 Ų5734%0.33631%0.313SS..  trans-81.3-21.6-179.9-63.3-17210.600112.8I137 E216 N240 R242 F243I137-Q218 HydrophobicContact CD1-CB 3.95Å; E216-Q218 PolarHBondContact O-N 2.96Å; Q218-N240 WeakPolarHBondContact CA-O 3.39Å; Q218-R242 PolarHBondContact O-N 3.46Å; Q218-F243 PolarHBondContact O-N 2.81Å
219L93.8Very high70.5Confident0 Ų055.2 Ų55.20%029%0.288CS..EExtended strand (participates in β ladder)trans-136.6130.9-176.6-172.8152.3000110.4F132 L135 I137 I145 G146 I217 I221 F243 I245F132-L219 HydrophobicContact CD1-CD1 3.87Å; F132-L219 HydrophobicContact CE1-CD1 4.19Å; F132-L219 HydrophobicContact CE1-CD2 4.19Å; L135-L219 HydrophobicContact CD1-CD1 3.96Å; I137-L219 HydrophobicContact CD1-CB 4.26Å; I137-L219 HydrophobicContact CG1-CD1 4.13Å; I145-L219 HydrophobicContact CD1-CB 4Å; I145-L219 HydrophobicContact CD1-CD2 4.43Å; I145-L219 HydrophobicContact CG2-CD2 3.7Å; G146-L219 PolarHBondContact N-O 2.91Å; I217-L219 WeakPolarHBondContact CG2-O 3.34Å; L219-I221 HydrophobicContact CD2-CD1 4.33Å; L219-I221 HydrophobicContact CD2-CG1 3.69Å; L219-F243 WeakPolarHBondContact CA-O 3.34Å; L219-F243 HydrophobicContact CB-CB 4.38Å; L219-F243 HydrophobicContact CD1-CB 4.1Å; L219-F243 HydrophobicContact CG-CB 4.06Å; L219-I245 HydrophobicContact CD1-CD1 3.97Å; L219-I245 HydrophobicContact CD1-CG1 4.45Å; L219-I245 HydrophobicContact CD2-CD1 4.16Å; L219-I245 HydrophobicContact CD2-CG1 4.49Å; L219-I245 HydrophobicContact CG-CD1 4.44Å
220I92.9Very high73.1Confident0 Ų052 Ų520%026%0.261CS..EExtended strand (participates in β ladder)trans-121.7136.7171.3-63.3168.7000109.6G146 I195 I217 C222 L231 L241 F243 V244 I245G146-I220 CarbonylContact O-C 3.56Å; G146-I220 WeakPolarHBondContact O-CA 3.4Å; I195-I220 HydrophobicContact CD1-CD1 3.32Å; I195-I220 HydrophobicContact CG1-CD1 3.65Å; I195-I220 HydrophobicContact CG2-CD1 4.47Å; I217-I220 HydrophobicContact CG2-CD1 4.33Å; I217-I220 HydrophobicContact CG2-CG1 3.6Å; I220-C222 VanDerWaalsContact CG2-SG 3.55Å; I220-L231 HydrophobicContact CD1-CD2 3.88Å; I220-L241 HydrophobicContact CB-CD1 4.23Å; I220-L241 HydrophobicContact CD1-CD1 3.68Å; I220-L241 HydrophobicContact CD1-CD2 3.88Å; I220-L241 HydrophobicContact CD1-CG 4.45Å; I220-L241 HydrophobicContact CG1-CD1 3.67Å; I220-F243 PolarHBondContact N-O 3.36Å; I220-F243 VanDerWaalsContact N-O 3.09Å; I220-V244 HydrophobicContact CB-CG2 4.36Å; I220-V244 CarbonylContact O-C 3.58Å; I220-V244 VanDerWaalsContact O-CA 3.31Å; I220-V244 WeakPolarHBondContact O-CA 3.41Å; I220-I245 PolarHBondContact O-N 3.27Å
221I93.2Very high75.7Confident0 Ų048 Ų480%024%0.235CC..EExtended strand (participates in β ladder)trans-100.5112.6169.6-52.1172.5000107.7L128 F132 I145 G146 Y148 L219 I245 M247 F268L128-I221 HydrophobicContact CD2-CD1 4.35Å; F132-I221 HydrophobicContact CE1-CD1 4.33Å; F132-I221 HydrophobicContact CZ-CD1 3.91Å; I145-I221 HydrophobicContact CG2-CD1 4.3Å; G146-I221 PolarHBondContact O-N 2.93Å; Y148-I221 PolarHBondContact N-O 3.46Å; L219-I221 HydrophobicContact CD2-CD1 4.33Å; L219-I221 HydrophobicContact CD2-CG1 3.69Å; I221-I245 CarbonylContact C-O 3.5Å; I221-I245 VanDerWaalsContact CA-O 3.28Å; I221-I245 WeakPolarHBondContact CA-O 3.26Å; I221-I245 HydrophobicContact CG1-CB 4.3Å; I221-M247 HydrophobicContact CG2-CE 3.66Å; I221-M247 HydrophobicContact CG2-CG 4.29Å; I221-F268 HydrophobicContact CG2-CD2 3.91Å; I221-F268 HydrophobicContact CG2-CE2 4.08Å
222C90.3Very high78.6Confident0 Ų041.2 Ų41.20%020%0.2CC..EExtended strand (participates in β ladder)trans-106.9150.5-179.8-78.10000110.8Y148 I220 V244 I245 I246 M247Y148-C222 WeakPolarHBondContact O-CA 3.08Å; I220-C222 VanDerWaalsContact CG2-SG 3.55Å; C222-V244 HydrophobicContact CB-CG1 4.27Å; C222-I245 PolarHBondContact N-O 3.45Å; C222-I246 CarbonylContact O-C 3.53Å; C222-I246 VanDerWaalsContact O-CA 3.32Å; C222-I246 WeakPolarHBondContact O-CA 3.45Å; C222-M247 PolarHBondContact O-N 2.82Å
223D86.8Confident81.4Confident3 Ų338.9 Ų38.92%0.01619%0.19CC..SBendtrans-81-30-178.9670.7000115.1Y148 S149 R150 R152 K227 M247 D248Y148-D223 PolarHBondContact O-N 3.46Å; S149-D223 WeakPolarHBondContact OG-CB 3.43Å; R150-D223 WeakPolarHBondContact CG-OD2 3.29Å; R150-D223 PolarHBondContact N-OD2 2.93Å; R150-D223 VanDerWaalsContact N-OD2 3.15Å; R152-D223 PolarHBondContact NH1-O 3.21Å; D223-K227 VanDerWaalsContact OD1-CD 3.29Å; D223-K227 WeakPolarHBondContact OD1-CD 3.25Å; D223-K227 WeakPolarHBondContact OD1-CE 3.35Å; D223-K227 IonicContact OD1-NZ 2.93Å; D223-K227 PolarHBondContact OD1-NZ 2.94Å; D223-K227 IonicContact OD2-NZ 2.75Å; D223-K227 PolarHBondContact OD2-NZ 3.07Å; D223-M247 HydrophobicContact CB-SD 4.2Å; D223-D248 WeakPolarHBondContact O-CB 3.32Å; D223-D248 VanDerWaalsContact O-CG 3.27Å; D223-D248 PolarHBondContact O-N 2.89Å; D223-D248 VanDerWaalsContact O-OD2 3.1Å
224T89.6Confident83.9Confident34 Ų3436.2 Ų36.221%0.20918%0.179CC..  trans-138.8146-169.856.70000112.5K226 K227 A228 D248T224-K226 PolarHBondContact O-N 3.2Å; T224-K227 PolarHBondContact O-N 3.5Å; T224-K227 VanDerWaalsContact O-N 3.13Å; T224-K227 WeakPolarHBondContact OG1-CB 3.44Å; T224-K227 PolarHBondContact OG1-N 2.78Å; T224-A228 PolarHBondContact O-N 2.83Å; T224-A228 VanDerWaalsContact O-N 3.08Å; T224-D248 WeakPolarHBondContact CG2-OD2 3.42Å
225P92.2Very high85.7Confident30 Ų3034 Ų3420%0.19516%0.162CC..Hα-helixtrans-56.6-34.8171.1-27.333.2000113.7A228 T229 I246 P249 V254P225-A228 PolarHBondContact O-N 2.97Å; P225-T229 VanDerWaalsContact O-CB 3.27Å; P225-T229 WeakPolarHBondContact O-CB 3.24Å; P225-T229 PolarHBondContact O-N 2.82Å; P225-T229 PolarHBondContact O-OG1 3.45Å; P225-I246 HydrophobicContact CG-CG2 4.23Å; P225-P249 WeakPolarHBondContact CG-O 3.48Å; P225-V254 HydrophobicContact CB-CB 4.26Å; P225-V254 HydrophobicContact CB-CG1 4.2Å; P225-V254 HydrophobicContact CB-CG2 4.26Å
226K91Very high86.7Confident160 Ų16034.6 Ų34.670%0.69617%0.17SC*.Hα-helixtrans-63.1-43.5176.9-176.1179.6178.3-177.40111.6T224 T229 N230T224-K226 PolarHBondContact O-N 3.2Å; K226-T229 PolarHBondContact O-N 3.45Å; K226-N230 WeakPolarHBondContact O-CB 3.48Å; K226-N230 PolarHBondContact O-N 2.96Å; K226-N230 PolarHBondContact O-ND2 3.42Å
227K87.8Confident86.2Confident18 Ų1838 Ų388%0.07820%0.199CC..Hα-helixtrans-67-44.4177.6-177.1-179.5-76.5176.10111.2Y148 D184 D223 T224 T229 N230 L231Y148-K227 HydrophobicContact CD1-CD 3.57Å; Y148-K227 HydrophobicContact CD1-CG 3.68Å; Y148-K227 HydrophobicContact CD2-CD 3.76Å; Y148-K227 HydrophobicContact CE1-CD 3.61Å; Y148-K227 HydrophobicContact CE1-CG 3.4Å; Y148-K227 HydrophobicContact CE2-CD 3.81Å; Y148-K227 HydrophobicContact CE2-CG 4.41Å; Y148-K227 HydrophobicContact CG-CD 3.65Å; Y148-K227 HydrophobicContact CG-CG 4.28Å; Y148-K227 VanDerWaalsContact O-CD 3.26Å; Y148-K227 WeakPolarHBondContact O-CD 3.26Å; Y148-K227 PolarHBondContact O-NZ 2.89Å; D184-K227 WeakPolarHBondContact OD1-CE 3.38Å; D184-K227 IonicContact OD1-NZ 3.4Å; D184-K227 PolarHBondContact OD1-NZ 2.85Å; D184-K227 IonicContact OD2-NZ 2.77Å; D223-K227 VanDerWaalsContact OD1-CD 3.29Å; D223-K227 WeakPolarHBondContact OD1-CD 3.25Å; D223-K227 WeakPolarHBondContact OD1-CE 3.35Å; D223-K227 IonicContact OD1-NZ 2.93Å; D223-K227 PolarHBondContact OD1-NZ 2.94Å; D223-K227 IonicContact OD2-NZ 2.75Å; D223-K227 PolarHBondContact OD2-NZ 3.07Å; T224-K227 PolarHBondContact O-N 3.5Å; T224-K227 VanDerWaalsContact O-N 3.13Å; T224-K227 WeakPolarHBondContact OG1-CB 3.44Å; T224-K227 PolarHBondContact OG1-N 2.78Å; K227-T229 PolarHBondContact O-N 3.49Å; K227-N230 PolarHBondContact O-N 2.89Å; K227-L231 WeakPolarHBondContact O-CB 3.31Å; K227-L231 PolarHBondContact O-N 2.8Å
228A90.7Very high85.2Confident0 Ų038.4 Ų38.40%020%0.202CC..Hα-helixtrans-59.4-46.8173.700000112.1T224 P225 N230 L231 F232 V244 I246 V254T224-A228 PolarHBondContact O-N 2.83Å; T224-A228 VanDerWaalsContact O-N 3.08Å; P225-A228 PolarHBondContact O-N 2.97Å; A228-N230 VanDerWaalsContact C-N 3.31Å; A228-N230 PolarHBondContact O-N 3.45Å; A228-L231 WeakPolarHBondContact O-CA 3.18Å; A228-L231 WeakPolarHBondContact O-CB 3.05Å; A228-L231 PolarHBondContact O-N 2.75Å; A228-L231 VanDerWaalsContact O-N 3.08Å; A228-F232 HydrophobicContact CB-CE2 4.06Å; A228-F232 HydrophobicContact CB-CZ 3.89Å; A228-F232 WeakPolarHBondContact O-CD1 3.37Å; A228-F232 VanDerWaalsContact O-CD2 3.3Å; A228-F232 WeakPolarHBondContact O-CD2 3.46Å; A228-F232 WeakPolarHBondContact O-CG 3.46Å; A228-F232 PolarHBondContact O-N 3.21Å; A228-V244 HydrophobicContact CB-CG1 4.17Å; A228-I246 HydrophobicContact CB-CD1 3.44Å; A228-I246 VanDerWaalsContact CB-CD1 3.44Å; A228-I246 HydrophobicContact CB-CG1 4.14Å; A228-V254 HydrophobicContact CB-CG2 4.22Å
229T91.3Very high84.1Confident33 Ų3344.2 Ų44.220%0.20223%0.229CC..Hα-helixtrans-59.1-40.9175.6-66.10000112.4P225 K226 K227 R233 H257P225-T229 VanDerWaalsContact O-CB 3.27Å; P225-T229 WeakPolarHBondContact O-CB 3.24Å; P225-T229 PolarHBondContact O-N 2.82Å; P225-T229 PolarHBondContact O-OG1 3.45Å; K226-T229 PolarHBondContact O-N 3.45Å; K227-T229 PolarHBondContact O-N 3.49Å; T229-R233 PolarHBondContact O-N 2.87Å; T229-H257 PolarHBondContact O-CE1 3.44Å
230N87.5Confident83.3Confident48 Ų4845.6 Ų45.626%0.25724%0.236SC..Hα-helixtrans-65.3-41.7174.5-78.7-20.7000111.6K226 K227 A228 R233 H234K226-N230 WeakPolarHBondContact O-CB 3.48Å; K226-N230 PolarHBondContact O-N 2.96Å; K226-N230 PolarHBondContact O-ND2 3.42Å; K227-N230 PolarHBondContact O-N 2.89Å; A228-N230 VanDerWaalsContact C-N 3.31Å; A228-N230 PolarHBondContact O-N 3.45Å; N230-R233 PolarHBondContact O-N 3Å; N230-R233 PolarHBondContact OD1-NH1 3.04Å; N230-H234 PolarHBondContact O-N 3.41Å; N230-H234 PolarHBondContact O-ND1 3.29Å
231L86.1Confident83.1Confident4 Ų445.7 Ų45.72%0.02124%0.237CC..Hα-helixtrans-59.7-48.9176.3178.764.9000111.3V191 I195 I220 K227 A228 R233 H234 L235 L241V191-L231 HydrophobicContact CG1-CD1 3.73Å; I195-L231 HydrophobicContact CD1-CD1 3.56Å; I195-L231 HydrophobicContact CD1-CD2 4.36Å; I220-L231 HydrophobicContact CD1-CD2 3.88Å; K227-L231 WeakPolarHBondContact O-CB 3.31Å; K227-L231 PolarHBondContact O-N 2.8Å; A228-L231 WeakPolarHBondContact O-CA 3.18Å; A228-L231 WeakPolarHBondContact O-CB 3.05Å; A228-L231 PolarHBondContact O-N 2.75Å; A228-L231 VanDerWaalsContact O-N 3.08Å; L231-R233 VanDerWaalsContact C-N 3.27Å; L231-R233 PolarHBondContact O-N 3.41Å; L231-H234 PolarHBondContact O-N 2.86Å; L231-H234 VanDerWaalsContact O-N 3.07Å; L231-L235 HydrophobicContact CD1-CD1 3.68Å; L231-L235 HydrophobicContact CD1-CD2 4.32Å; L231-L235 HydrophobicContact CD1-CG 3.74Å; L231-L235 HydrophobicContact CD2-CD1 4.05Å; L231-L235 HydrophobicContact CG-CD1 3.53Å; L231-L235 HydrophobicContact CG-CG 4.03Å; L231-L235 WeakPolarHBondContact O-CB 3.41Å; L231-L235 WeakPolarHBondContact O-CG 3.27Å; L231-L235 PolarHBondContact O-N 3.09Å; L231-L241 HydrophobicContact CD2-CD2 4.27Å
232F88.8Confident83Confident2 Ų250.4 Ų50.41%0.00925%0.254CS..Hα-helixtrans-56.8-39.7179-57.3-24.3000112.7A228 H234 G236 V244 V254 H257 I261 V263 V265A228-F232 HydrophobicContact CB-CE2 4.06Å; A228-F232 HydrophobicContact CB-CZ 3.89Å; A228-F232 WeakPolarHBondContact O-CD1 3.37Å; A228-F232 VanDerWaalsContact O-CD2 3.3Å; A228-F232 WeakPolarHBondContact O-CD2 3.46Å; A228-F232 WeakPolarHBondContact O-CG 3.46Å; A228-F232 PolarHBondContact O-N 3.21Å; F232-H234 VanDerWaalsContact C-N 3.3Å; F232-H234 PolarHBondContact O-N 3.14Å; F232-G236 PolarHBondContact O-N 2.58Å; F232-V244 HydrophobicContact CE1-CB 4.24Å; F232-V244 HydrophobicContact CE1-CG2 3.85Å; F232-V244 HydrophobicContact CZ-CB 4.22Å; F232-V244 HydrophobicContact CZ-CG1 4.33Å; F232-V244 HydrophobicContact CZ-CG2 4.33Å; F232-V254 HydrophobicContact CE2-CG2 3.94Å; F232-H257 HydrophobicContact CD2-CB 4.31Å; F232-H257 AromaticContact CD2-CG 3.97Å; F232-H257 AromaticContact CD2-ND1 3.88Å; F232-I261 HydrophobicContact CB-CD1 3.59Å; F232-I261 HydrophobicContact CB-CG1 4.43Å; F232-I261 HydrophobicContact CD1-CD1 3.63Å; F232-I261 HydrophobicContact CG-CD1 3.81Å; F232-V263 HydrophobicContact CE1-CB 4.39Å; F232-V263 HydrophobicContact CE1-CG1 3.97Å; F232-V263 HydrophobicContact CZ-CG1 4.4Å; F232-V265 HydrophobicContact CE2-CG2 4Å; F232-V265 HydrophobicContact CZ-CG2 3.73Å
233R86.3Confident83.2Confident146 Ų14651.2 Ų51.255%0.55126%0.258SS*.Hα-helixtrans-62.9-33.3178.2-166-175.8-56.5109.15.1113.5T229 N230 L231T229-R233 PolarHBondContact O-N 2.87Å; N230-R233 PolarHBondContact O-N 3Å; N230-R233 PolarHBondContact OD1-NH1 3.04Å; L231-R233 VanDerWaalsContact C-N 3.27Å; L231-R233 PolarHBondContact O-N 3.41Å
234H81Confident83.6Confident83 Ų8351.1 Ų51.138%0.38426%0.257SS..Hα-helixtrans-95.5-30.2-176.2-63.981.5000112.8N188 C192 N230 L231 F232N188-H234 HydrophobicContact CB-CB 4.26Å; N188-H234 VanDerWaalsContact CG-CE1 3.5Å; N188-H234 PolarHBondContact ND2-CE1 3.02Å; N188-H234 PolarHBondContact ND2-NE2 3.44Å; N188-H234 VanDerWaalsContact ND2-NE2 3.19Å; C192-H234 VanDerWaalsContact SG-CB 3.51Å; N230-H234 PolarHBondContact O-N 3.41Å; N230-H234 PolarHBondContact O-ND1 3.29Å; L231-H234 PolarHBondContact O-N 2.86Å; L231-H234 VanDerWaalsContact O-N 3.07Å; F232-H234 VanDerWaalsContact C-N 3.3Å; F232-H234 PolarHBondContact O-N 3.14Å
235L77.1Confident83.8Confident13 Ų1349.5 Ų49.57%0.06825%0.247CC..Hα-helixtrans-67.1-38.4176.5-78.2179000112.3C192 I195 L231 T238 L241C192-L235 HydrophobicContact CB-CD2 4.21Å; I195-L235 HydrophobicContact CB-CD2 4.28Å; I195-L235 HydrophobicContact CD1-CD1 4.34Å; I195-L235 HydrophobicContact CD1-CD2 3.99Å; I195-L235 HydrophobicContact CG2-CD2 4.04Å; L231-L235 HydrophobicContact CD1-CD1 3.68Å; L231-L235 HydrophobicContact CD1-CD2 4.32Å; L231-L235 HydrophobicContact CD1-CG 3.74Å; L231-L235 HydrophobicContact CD2-CD1 4.05Å; L231-L235 HydrophobicContact CG-CD1 3.53Å; L231-L235 HydrophobicContact CG-CG 4.03Å; L231-L235 WeakPolarHBondContact O-CB 3.41Å; L231-L235 WeakPolarHBondContact O-CG 3.27Å; L231-L235 PolarHBondContact O-N 3.09Å; L235-T238 HydrophobicContact CB-CG2 3.69Å; L235-T238 HydrophobicContact CD2-CG2 4.26Å; L235-T238 HydrophobicContact CG-CG2 4.39Å; L235-T238 WeakPolarHBondContact O-CG2 3.29Å; L235-L241 HydrophobicContact CD1-CD2 3.38Å
236G66.3Low83.9Confident31 Ų3148 Ų4832%0.3224%0.238SC..  trans69.8-159.6-169.800000111.8F232 T238F232-G236 PolarHBondContact O-N 2.58Å; G236-T238 PolarHBondContact O-N 2.72Å
237S62.5Low83.8Confident114 Ų11440.4 Ų40.480%0.79721%0.205SC*.SBendtrans-75109.4172.7-1750000108.8
238T64.1Low83.8Confident16 Ų1641.1 Ų41.110%0.09821%0.209CC..  trans-112.4137.1179.781.10000109.9H196 L235 G236 N240 L241H196-T238 VanDerWaalsContact NE2-CG2 3.34Å; H196-T238 WeakPolarHBondContact NE2-CG2 3.5Å; L235-T238 HydrophobicContact CB-CG2 3.69Å; L235-T238 HydrophobicContact CD2-CG2 4.26Å; L235-T238 HydrophobicContact CG-CG2 4.39Å; L235-T238 WeakPolarHBondContact O-CG2 3.29Å; G236-T238 PolarHBondContact O-N 2.72Å; T238-N240 PolarHBondContact O-N 2.77Å; T238-L241 PolarHBondContact OG1-N 3.37Å
239E66.9Low83.8Confident193 Ų19344.5 Ų44.590%0.90223%0.232SC*.SBendtrans-75.3-14.8172.7-65-172.9167.300112.5
240N76.7Confident83.8Confident30 Ų3044.9 Ų44.916%0.1623%0.232CC..SBendtrans-95.1-52.8-163.6-65.7-4000113.8E216 Q218 T238 R242E216-N240 HydrophobicContact CB-CB 3.96Å; E216-N240 HydrophobicContact CG-CB 4.21Å; E216-N240 VanDerWaalsContact CG-ND2 3.27Å; E216-N240 WeakPolarHBondContact CG-ND2 3.42Å; E216-N240 PolarHBondContact OE1-ND2 2.99Å; E216-N240 PolarHBondContact OE1-OD1 2.88Å; E216-N240 PolarHBondContact OE2-OD1 2.61Å; E216-N240 VanDerWaalsContact OE2-OD1 3.09Å; Q218-N240 WeakPolarHBondContact CA-O 3.39Å; T238-N240 PolarHBondContact O-N 2.77Å; N240-R242 PolarHBondContact O-N 3.16Å
241L88.1Confident84.1Confident1 Ų146.6 Ų46.61%0.00524%0.241CC..  trans-76.5110.7-179.3-177.664.9000108.7I220 L231 L235 T238 F243 V244 V263I220-L241 HydrophobicContact CB-CD1 4.23Å; I220-L241 HydrophobicContact CD1-CD1 3.68Å; I220-L241 HydrophobicContact CD1-CD2 3.88Å; I220-L241 HydrophobicContact CD1-CG 4.45Å; I220-L241 HydrophobicContact CG1-CD1 3.67Å; L231-L241 HydrophobicContact CD2-CD2 4.27Å; L235-L241 HydrophobicContact CD1-CD2 3.38Å; T238-L241 PolarHBondContact OG1-N 3.37Å; L241-F243 WeakPolarHBondContact CD1-O 3.44Å; L241-V244 HydrophobicContact CD1-CG2 4.36Å; L241-V244 HydrophobicContact CD2-CG2 3.81Å; L241-V244 HydrophobicContact CG-CG2 4.28Å; L241-V263 HydrophobicContact CD2-CG2 4.28Å; L241-V263 HydrophobicContact CG-CG2 4.27Å; L241-V263 WeakPolarHBondContact O-CG2 3.29Å
242R91.6Very high84.5Confident99 Ų9952.1 Ų52.137%0.37427%0.267SS..  trans-97.3-34.4-176.9-66.4168.763-154.4-1.5112Q218 N240 K264Q218-R242 PolarHBondContact O-N 3.46Å; N240-R242 PolarHBondContact O-N 3.16Å; R242-K264 PolarHBondContact O-N 3.14Å
243F94.9Very high84.8Confident18 Ų1856.8 Ų56.88%0.07930%0.296CS..EExtended strand (participates in β ladder)trans-134138.2-172-53.3-78.6000112L135 I137 Q218 L219 I220 L241 K264 L266L135-F243 HydrophobicContact CB-CD2 4.5Å; L135-F243 HydrophobicContact CB-CE1 4.29Å; L135-F243 HydrophobicContact CB-CE2 4.11Å; L135-F243 HydrophobicContact CB-CZ 4Å; L135-F243 HydrophobicContact CD1-CD1 4.23Å; L135-F243 HydrophobicContact CD1-CG 4.24Å; L135-F243 HydrophobicContact CD2-CD1 4.22Å; L135-F243 HydrophobicContact CD2-CE1 3.98Å; L135-F243 HydrophobicContact CD2-CZ 4.49Å; L135-F243 WeakPolarHBondContact O-CZ 3.43Å; I137-F243 HydrophobicContact CD1-CD2 3.95Å; I137-F243 HydrophobicContact CD1-CE2 4.03Å; Q218-F243 PolarHBondContact O-N 2.81Å; L219-F243 WeakPolarHBondContact CA-O 3.34Å; L219-F243 HydrophobicContact CB-CB 4.38Å; L219-F243 HydrophobicContact CD1-CB 4.1Å; L219-F243 HydrophobicContact CG-CB 4.06Å; I220-F243 PolarHBondContact N-O 3.36Å; I220-F243 VanDerWaalsContact N-O 3.09Å; L241-F243 WeakPolarHBondContact CD1-O 3.44Å; F243-K264 WeakPolarHBondContact CA-O 3.34Å; F243-K264 HydrophobicContact CD1-CB 3.85Å; F243-K264 HydrophobicContact CD1-CD 4.1Å; F243-K264 HydrophobicContact CD1-CG 4.43Å; F243-K264 HydrophobicContact CE1-CB 4.19Å; F243-K264 HydrophobicContact CE1-CD 3.94Å; F243-L266 HydrophobicContact CD1-CD1 4.15Å
244V94.7Very high85.3Confident0 Ų050 Ų500%027%0.27CS..EExtended strand (participates in β ladder)trans-123.9116.2163.7171.40000109I220 C222 A228 F232 L241 I246 V263 K264 V265 L266I220-V244 HydrophobicContact CB-CG2 4.36Å; I220-V244 CarbonylContact O-C 3.58Å; I220-V244 VanDerWaalsContact O-CA 3.31Å; I220-V244 WeakPolarHBondContact O-CA 3.41Å; C222-V244 HydrophobicContact CB-CG1 4.27Å; A228-V244 HydrophobicContact CB-CG1 4.17Å; F232-V244 HydrophobicContact CE1-CB 4.24Å; F232-V244 HydrophobicContact CE1-CG2 3.85Å; F232-V244 HydrophobicContact CZ-CB 4.22Å; F232-V244 HydrophobicContact CZ-CG1 4.33Å; F232-V244 HydrophobicContact CZ-CG2 4.33Å; L241-V244 HydrophobicContact CD1-CG2 4.36Å; L241-V244 HydrophobicContact CD2-CG2 3.81Å; L241-V244 HydrophobicContact CG-CG2 4.28Å; V244-I246 HydrophobicContact CG1-CD1 4.37Å; V244-I246 HydrophobicContact CG1-CG1 3.82Å; V244-V263 HydrophobicContact CB-CG1 4.03Å; V244-V263 HydrophobicContact CG2-CG1 3.7Å; V244-K264 PolarHBondContact N-O 3.23Å; V244-V265 CarbonylContact O-C 3.57Å; V244-V265 WeakPolarHBondContact O-CA 3.43Å; V244-L266 PolarHBondContact O-N 2.87Å
245I95.1Very high86Confident0 Ų048.4 Ų48.40%026%0.264CS..EExtended strand (participates in β ladder)trans-91.4126.8171.2-59.5179000107L128 F132 L219 I220 I221 C222 L266 F268 C271L128-I245 HydrophobicContact CD1-CD1 4.34Å; F132-I245 HydrophobicContact CD1-CD1 4.32Å; F132-I245 HydrophobicContact CE1-CD1 3.84Å; L219-I245 HydrophobicContact CD1-CD1 3.97Å; L219-I245 HydrophobicContact CD1-CG1 4.45Å; L219-I245 HydrophobicContact CD2-CD1 4.16Å; L219-I245 HydrophobicContact CD2-CG1 4.49Å; L219-I245 HydrophobicContact CG-CD1 4.44Å; I220-I245 PolarHBondContact O-N 3.27Å; I221-I245 CarbonylContact C-O 3.5Å; I221-I245 VanDerWaalsContact CA-O 3.28Å; I221-I245 WeakPolarHBondContact CA-O 3.26Å; I221-I245 HydrophobicContact CG1-CB 4.3Å; C222-I245 PolarHBondContact N-O 3.45Å; I245-L266 CarbonylContact C-O 3.56Å; I245-L266 WeakPolarHBondContact CA-O 3.41Å; I245-L266 HydrophobicContact CG1-CB 4.17Å; I245-L266 HydrophobicContact CG1-CD1 4.31Å; I245-F268 HydrophobicContact CG2-CB 3.84Å; I245-F268 HydrophobicContact CG2-CD2 3.81Å; I245-F268 HydrophobicContact CG2-CG 4.26Å; I245-C271 HydrophobicContact CD1-CB 4.46Å
246I93.2Very high86.9Confident0 Ų052 Ų520%028%0.284CS..EExtended strand (participates in β ladder)trans-110.3131.4179.8-53.7-176.8000108.7C222 P225 A228 V244 D248 I250 V254 V265 L266 F268C222-I246 CarbonylContact O-C 3.53Å; C222-I246 VanDerWaalsContact O-CA 3.32Å; C222-I246 WeakPolarHBondContact O-CA 3.45Å; P225-I246 HydrophobicContact CG-CG2 4.23Å; A228-I246 HydrophobicContact CB-CD1 3.44Å; A228-I246 VanDerWaalsContact CB-CD1 3.44Å; A228-I246 HydrophobicContact CB-CG1 4.14Å; V244-I246 HydrophobicContact CG1-CD1 4.37Å; V244-I246 HydrophobicContact CG1-CG1 3.82Å; I246-D248 WeakPolarHBondContact CG2-O 3.34Å; I246-I250 HydrophobicContact CB-CG2 3.52Å; I246-I250 HydrophobicContact CD1-CG2 3.76Å; I246-I250 HydrophobicContact CG1-CG2 4.05Å; I246-I250 HydrophobicContact CG2-CG2 3.87Å; I246-V254 HydrophobicContact CD1-CG1 4.43Å; I246-V254 HydrophobicContact CD1-CG2 3.83Å; I246-V265 HydrophobicContact CD1-CG1 3.53Å; I246-V265 HydrophobicContact CG1-CG1 3.99Å; I246-L266 PolarHBondContact N-O 3.35Å; I246-F268 WeakPolarHBondContact O-CB 3.39Å; I246-F268 PolarHBondContact O-N 2.89Å
247M89.5Confident88.2Confident0 Ų053.2 Ų53.20%028%0.281CS..SBendtrans-66.7-69.5174.7-63.1174.2177.300109.8S149 V155 E163 I221 C222 D223 Q267 F268S149-M247 PolarHBondContact OG-SD 2.93Å; V155-M247 HydrophobicContact CG2-CB 4.38Å; E163-M247 HydrophobicContact CB-CB 4.26Å; E163-M247 HydrophobicContact CB-CG 4.36Å; E163-M247 VanDerWaalsContact CD-O 3.31Å; E163-M247 WeakPolarHBondContact OE2-CA 3.42Å; E163-M247 WeakPolarHBondContact OE2-CB 3.47Å; I221-M247 HydrophobicContact CG2-CE 3.66Å; I221-M247 HydrophobicContact CG2-CG 4.29Å; C222-M247 PolarHBondContact O-N 2.82Å; D223-M247 HydrophobicContact CB-SD 4.2Å; M247-Q267 PolarHBondContact O-NE2 3.34Å; M247-F268 HydrophobicContact CE-CE2 4.49Å; M247-F268 HydrophobicContact CG-CB 4.44Å; M247-F268 HydrophobicContact CG-CD2 4.14Å; M247-F268 HydrophobicContact CG-CG 4.3Å
248D88.2Confident89.7Confident32 Ų3247.8 Ų47.817%0.17124%0.243CC..SBendtrans-56.2153.3180-78.8-35.1000114R152 V155 D223 T224 I246 I250 Q267R152-D248 IonicContact CZ-OD1 3.32Å; R152-D248 IonicContact CZ-OD2 2.66Å; R152-D248 IonicContact NH1-OD1 3.03Å; R152-D248 IonicContact NH1-OD2 3.8Å; R152-D248 PolarHBondContact NH1-OD2 2.69Å; R152-D248 IonicContact NH2-OD1 3.7Å; R152-D248 PolarHBondContact NH2-OD1 3.07Å; R152-D248 IonicContact NH2-OD2 3.71Å; R152-D248 PolarHBondContact NH2-OD2 3.05Å; R152-D248 VanDerWaalsContact NH2-OD2 3.12Å; V155-D248 WeakPolarHBondContact CG2-OD1 3.37Å; D223-D248 WeakPolarHBondContact O-CB 3.32Å; D223-D248 VanDerWaalsContact O-CG 3.27Å; D223-D248 PolarHBondContact O-N 2.89Å; D223-D248 VanDerWaalsContact O-OD2 3.1Å; T224-D248 WeakPolarHBondContact CG2-OD2 3.42Å; I246-D248 WeakPolarHBondContact CG2-O 3.34Å; D248-I250 PolarHBondContact O-N 2.95Å; D248-Q267 PolarHBondContact O-OE1 2.74Å
249P89.2Confident91.1Very high72 Ų7250.1 Ų50.147%0.46826%0.264SS..PPolyproline II helixtrans-51.8126.5-179.6-27.736.2000112.2V155 P225V155-P249 HydrophobicContact CG1-CG 4.17Å; P225-P249 WeakPolarHBondContact CG-O 3.48Å
250I92.2Very high92.3Very high40 Ų4045.2 Ų45.221%0.20525%0.251CS..PPolyproline II helixtrans-90.6152.4177.367.7-176.8000111.9I246 D248 V254 I255 V265 Q267I246-I250 HydrophobicContact CB-CG2 3.52Å; I246-I250 HydrophobicContact CD1-CG2 3.76Å; I246-I250 HydrophobicContact CG1-CG2 4.05Å; I246-I250 HydrophobicContact CG2-CG2 3.87Å; D248-I250 PolarHBondContact O-N 2.95Å; I250-V254 HydrophobicContact CB-CG1 3.78Å; I250-V254 HydrophobicContact CG2-CG1 4.17Å; I250-I255 HydrophobicContact CD1-CD1 3.9Å; I250-I255 HydrophobicContact CD1-CG1 4Å; I250-I255 HydrophobicContact CG1-CD1 4.19Å; I250-I255 HydrophobicContact CG1-CG1 4.46Å; I250-V265 HydrophobicContact CD1-CG1 4.23Å; I250-V265 HydrophobicContact CG2-CG1 4.37Å; I250-Q267 HydrophobicContact CD1-CB 3.94Å; I250-Q267 HydrophobicContact CG1-CB 4.3Å
251D93.3Very high92.9Very high85 Ų8544.8 Ų44.846%0.45525%0.248SC..  trans-116.5172.9171.36717.3000111.3T253 V254 I255D251-T253 PolarHBondContact O-N 2.8Å; D251-T253 WeakPolarHBondContact OD1-CA 3.4Å; D251-T253 WeakPolarHBondContact OD1-CB 3.44Å; D251-T253 PolarHBondContact OD1-N 3.46Å; D251-T253 PolarHBondContact OD1-OG1 3.46Å; D251-V254 VanDerWaalsContact O-CG1 3.32Å; D251-V254 WeakPolarHBondContact O-CG1 3.3Å; D251-V254 PolarHBondContact O-N 2.8Å; D251-V254 PolarHBondContact OD1-N 3.38Å; D251-I255 WeakPolarHBondContact O-CD1 3.14Å; D251-I255 WeakPolarHBondContact O-CG1 3.2Å; D251-I255 PolarHBondContact O-N 2.92Å
252Q95.1Very high93Very high119 Ų11947.5 Ų47.556%0.55628%0.277SS*.Hα-helixtrans-62.2-28.5178.9-166.16147.100112.2I255 D256Q252-I255 PolarHBondContact O-N 2.96Å; Q252-D256 PolarHBondContact NE2-OD1 3.27Å; Q252-D256 WeakPolarHBondContact O-CB 3.44Å; Q252-D256 PolarHBondContact O-N 2.73Å
253T95.3Very high93Very high101 Ų10142.9 Ų42.962%0.6226%0.26SS*.Hα-helixtrans-62.6-48.1-178.9-42.30000111.8D251 I255 H257D251-T253 PolarHBondContact O-N 2.8Å; D251-T253 WeakPolarHBondContact OD1-CA 3.4Å; D251-T253 WeakPolarHBondContact OD1-CB 3.44Å; D251-T253 PolarHBondContact OD1-N 3.46Å; D251-T253 PolarHBondContact OD1-OG1 3.46Å; T253-I255 VanDerWaalsContact C-N 3.34Å; T253-H257 WeakPolarHBondContact O-CB 3.18Å; T253-H257 PolarHBondContact O-N 3.28Å; T253-H257 VanDerWaalsContact O-N 3.09Å
254V95.3Very high93.1Very high2 Ų247.3 Ų47.31%0.01228%0.279CS..Hα-helixtrans-70.7-33.217966.60000111.6P225 A228 F232 I246 I250 D251 G258P225-V254 HydrophobicContact CB-CB 4.26Å; P225-V254 HydrophobicContact CB-CG1 4.2Å; P225-V254 HydrophobicContact CB-CG2 4.26Å; A228-V254 HydrophobicContact CB-CG2 4.22Å; F232-V254 HydrophobicContact CE2-CG2 3.94Å; I246-V254 HydrophobicContact CD1-CG1 4.43Å; I246-V254 HydrophobicContact CD1-CG2 3.83Å; I250-V254 HydrophobicContact CB-CG1 3.78Å; I250-V254 HydrophobicContact CG2-CG1 4.17Å; D251-V254 VanDerWaalsContact O-CG1 3.32Å; D251-V254 WeakPolarHBondContact O-CG1 3.3Å; D251-V254 PolarHBondContact O-N 2.8Å; D251-V254 PolarHBondContact OD1-N 3.38Å; V254-G258 PolarHBondContact O-N 3.43Å
255I96.5Very high93.2Very high50 Ų5047.9 Ų47.926%0.25628%0.282SS..Hα-helixtrans-63.3-50.2175.2-64.9167.4000110.6I250 D251 Q252 T253 H257 G258 A259 V265I250-I255 HydrophobicContact CD1-CD1 3.9Å; I250-I255 HydrophobicContact CD1-CG1 4Å; I250-I255 HydrophobicContact CG1-CD1 4.19Å; I250-I255 HydrophobicContact CG1-CG1 4.46Å; D251-I255 WeakPolarHBondContact O-CD1 3.14Å; D251-I255 WeakPolarHBondContact O-CG1 3.2Å; D251-I255 PolarHBondContact O-N 2.92Å; Q252-I255 PolarHBondContact O-N 2.96Å; T253-I255 VanDerWaalsContact C-N 3.34Å; I255-H257 VanDerWaalsContact C-N 3.32Å; I255-H257 PolarHBondContact O-N 3.14Å; I255-G258 PolarHBondContact O-N 2.76Å; I255-A259 WeakPolarHBondContact O-CB 3.32Å; I255-A259 PolarHBondContact O-N 2.69Å; I255-V265 HydrophobicContact CG1-CB 4.26Å; I255-V265 HydrophobicContact CG1-CG1 4.39Å
256D96.2Very high93.2Very high90 Ų9048.8 Ų48.848%0.48129%0.287SS..Hα-helixtrans-63.8-38.3179.9-69.2-14.1000111.6Q252 A259 S260Q252-D256 PolarHBondContact NE2-OD1 3.27Å; Q252-D256 WeakPolarHBondContact O-CB 3.44Å; Q252-D256 PolarHBondContact O-N 2.73Å; D256-A259 PolarHBondContact O-N 3.44Å; D256-S260 PolarHBondContact O-N 2.82Å
257H93.5Very high93.3Very high55 Ų5549.4 Ų49.426%0.25529%0.29SS..Hα-helixtrans-65.5-44.3176.5-172.3-169.2000111.8T229 F232 T253 I255 A259 S260T229-H257 PolarHBondContact O-CE1 3.44Å; F232-H257 HydrophobicContact CD2-CB 4.31Å; F232-H257 AromaticContact CD2-CG 3.97Å; F232-H257 AromaticContact CD2-ND1 3.88Å; T253-H257 WeakPolarHBondContact O-CB 3.18Å; T253-H257 PolarHBondContact O-N 3.28Å; T253-H257 VanDerWaalsContact O-N 3.09Å; I255-H257 VanDerWaalsContact C-N 3.32Å; I255-H257 PolarHBondContact O-N 3.14Å; H257-A259 VanDerWaalsContact C-N 3.35Å; H257-A259 PolarHBondContact O-N 3.03Å; H257-S260 PolarHBondContact O-N 3.37Å; H257-S260 PolarHBondContact O-OG 3.02Å
258G93.8Very high93.4Very high0 Ų049.4 Ų49.40%029%0.29CS..Hα-helixtrans-59.4-46.6172.800000111.7V254 I255 S260 I261 G262 V263V254-G258 PolarHBondContact O-N 3.43Å; I255-G258 PolarHBondContact O-N 2.76Å; G258-S260 VanDerWaalsContact C-N 3.25Å; G258-S260 PolarHBondContact O-N 3.32Å; G258-I261 WeakPolarHBondContact O-CG1 3.46Å; G258-I261 PolarHBondContact O-N 2.92Å; G258-G262 PolarHBondContact O-N 3.23Å; G258-V263 CarbonylContact C-O 2.94Å; G258-V263 WeakPolarHBondContact CA-O 3.07Å; G258-V263 PolarHBondContact O-N 3.3Å; G258-V263 VanDerWaalsContact O-O 3.12Å
259A93.4Very high93.5Very high65 Ų6548.5 Ų48.554%0.53729%0.285SS..Hα-helixtrans-59.5-35.7178.400000112.6I255 D256 H257 I261 G262 V263I255-A259 WeakPolarHBondContact O-CB 3.32Å; I255-A259 PolarHBondContact O-N 2.69Å; D256-A259 PolarHBondContact O-N 3.44Å; H257-A259 VanDerWaalsContact C-N 3.35Å; H257-A259 PolarHBondContact O-N 3.03Å; A259-I261 PolarHBondContact O-N 2.73Å; A259-G262 PolarHBondContact O-N 2.76Å; A259-G262 VanDerWaalsContact O-N 3.12Å; A259-V263 PolarHBondContact N-O 2.81Å
260S92.6Very high93.6Very high91 Ų9150 Ų5064%0.63629%0.286SS*.Hα-helixtrans-63-19.7177.978.60000114.5D256 H257 G258D256-S260 PolarHBondContact O-N 2.82Å; H257-S260 PolarHBondContact O-N 3.37Å; H257-S260 PolarHBondContact O-OG 3.02Å; G258-S260 VanDerWaalsContact C-N 3.25Å; G258-S260 PolarHBondContact O-N 3.32Å
261I89.3Confident93.8Very high20 Ų2048.1 Ų48.110%0.10328%0.276CS..THydrogen-bonded Turntrans-114.212.9176.564157.7000113.1F232 G258 A259 V263F232-I261 HydrophobicContact CB-CD1 3.59Å; F232-I261 HydrophobicContact CB-CG1 4.43Å; F232-I261 HydrophobicContact CD1-CD1 3.63Å; F232-I261 HydrophobicContact CG-CD1 3.81Å; G258-I261 WeakPolarHBondContact O-CG1 3.46Å; G258-I261 PolarHBondContact O-N 2.92Å; A259-I261 PolarHBondContact O-N 2.73Å; I261-V263 HydrophobicContact CD1-CB 4.46Å; I261-V263 HydrophobicContact CD1-CG2 3.75Å; I261-V263 HydrophobicContact CG1-CB 4.28Å; I261-V263 HydrophobicContact CG1-CG2 3.89Å
262G89.9Confident93.8Very high59 Ų5944.2 Ų44.261%0.60826%0.255SS*.THydrogen-bonded Turntrans82.711.1178.300000115.7G258 A259G258-G262 PolarHBondContact O-N 3.23Å; A259-G262 PolarHBondContact O-N 2.76Å; A259-G262 VanDerWaalsContact O-N 3.12Å
263V92.7Very high93.7Very high2 Ų242.5 Ų42.51%0.01224%0.244CC..PPolyproline II helixtrans-101.3125.1-178.3178.60000110.7F232 L241 V244 G258 A259 I261 V265F232-V263 HydrophobicContact CE1-CB 4.39Å; F232-V263 HydrophobicContact CE1-CG1 3.97Å; F232-V263 HydrophobicContact CZ-CG1 4.4Å; L241-V263 HydrophobicContact CD2-CG2 4.28Å; L241-V263 HydrophobicContact CG-CG2 4.27Å; L241-V263 WeakPolarHBondContact O-CG2 3.29Å; V244-V263 HydrophobicContact CB-CG1 4.03Å; V244-V263 HydrophobicContact CG2-CG1 3.7Å; G258-V263 CarbonylContact C-O 2.94Å; G258-V263 WeakPolarHBondContact CA-O 3.07Å; G258-V263 PolarHBondContact O-N 3.3Å; G258-V263 VanDerWaalsContact O-O 3.12Å; A259-V263 PolarHBondContact N-O 2.81Å; I261-V263 HydrophobicContact CD1-CB 4.46Å; I261-V263 HydrophobicContact CD1-CG2 3.75Å; I261-V263 HydrophobicContact CG1-CB 4.28Å; I261-V263 HydrophobicContact CG1-CG2 3.89Å; V263-V265 PolarHBondContact O-N 2.82Å
264K95.6Very high93.7Very high111 Ų11141.9 Ų41.948%0.48323%0.234SC..EExtended strand (participates in β ladder)trans-81.7119172.5-172-175.7-171.4-170.40110.4R242 F243 V244 L266R242-K264 PolarHBondContact O-N 3.14Å; F243-K264 WeakPolarHBondContact CA-O 3.34Å; F243-K264 HydrophobicContact CD1-CB 3.85Å; F243-K264 HydrophobicContact CD1-CD 4.1Å; F243-K264 HydrophobicContact CD1-CG 4.43Å; F243-K264 HydrophobicContact CE1-CB 4.19Å; F243-K264 HydrophobicContact CE1-CD 3.94Å; V244-K264 PolarHBondContact N-O 3.23Å; K264-L266 HydrophobicContact CD-CD2 4.17Å; K264-L266 HydrophobicContact CD-CG 4.48Å; K264-L266 HydrophobicContact CG-CD2 4.3Å; K264-L266 HydrophobicContact CG-CG 4.34Å
265V96.8Very high93.7Very high12 Ų1241.8 Ų41.87%0.07323%0.233CC..EExtended strand (participates in β ladder)trans-91.1133.7176.4-174.20000110.4F232 V244 I246 I250 I255 V263F232-V265 HydrophobicContact CE2-CG2 4Å; F232-V265 HydrophobicContact CZ-CG2 3.73Å; V244-V265 CarbonylContact O-C 3.57Å; V244-V265 WeakPolarHBondContact O-CA 3.43Å; I246-V265 HydrophobicContact CD1-CG1 3.53Å; I246-V265 HydrophobicContact CG1-CG1 3.99Å; I250-V265 HydrophobicContact CD1-CG1 4.23Å; I250-V265 HydrophobicContact CG2-CG1 4.37Å; I255-V265 HydrophobicContact CG1-CB 4.26Å; I255-V265 HydrophobicContact CG1-CG1 4.39Å; V263-V265 PolarHBondContact O-N 2.82Å
266L96.2Very high93.6Very high19 Ų1942 Ų4210%0.09924%0.238CC..EExtended strand (participates in β ladder)trans-134.1150.2-175-63.7165.5000110.5Y131 L135 F243 V244 I245 I246 K264Y131-L266 HydrophobicContact CE1-CD1 4.21Å; L135-L266 HydrophobicContact CD1-CD1 3.62Å; L135-L266 HydrophobicContact CD2-CD1 3.75Å; L135-L266 HydrophobicContact CG-CD1 4.35Å; F243-L266 HydrophobicContact CD1-CD1 4.15Å; V244-L266 PolarHBondContact O-N 2.87Å; I245-L266 CarbonylContact C-O 3.56Å; I245-L266 WeakPolarHBondContact CA-O 3.41Å; I245-L266 HydrophobicContact CG1-CB 4.17Å; I245-L266 HydrophobicContact CG1-CD1 4.31Å; I246-L266 PolarHBondContact N-O 3.35Å; K264-L266 HydrophobicContact CD-CD2 4.17Å; K264-L266 HydrophobicContact CD-CG 4.48Å; K264-L266 HydrophobicContact CG-CD2 4.3Å; K264-L266 HydrophobicContact CG-CG 4.34Å
267Q94Very high93.6Very high13 Ų1343.1 Ų43.16%0.06125%0.249CC..EExtended strand (participates in β ladder)trans-89.9133176.9-179.768.640.500110.3M247 D248 I250 D269 Q270 C271M247-Q267 PolarHBondContact O-NE2 3.34Å; D248-Q267 PolarHBondContact O-OE1 2.74Å; I250-Q267 HydrophobicContact CD1-CB 3.94Å; I250-Q267 HydrophobicContact CG1-CB 4.3Å; Q267-D269 WeakPolarHBondContact CG-OD1 3.29Å; Q267-Q270 HydrophobicContact CB-CB 4.24Å; Q267-Q270 HydrophobicContact CB-CG 4.03Å; Q267-Q270 HydrophobicContact CG-CG 4.06Å; Q267-Q270 PolarHBondContact O-N 3.25Å; Q267-C271 PolarHBondContact O-N 3.32Å; Q267-C271 VanDerWaalsContact O-N 3.1Å; Q267-C271 PolarHBondContact O-SG 3.48Å
268F92.5Very high93.7Very high0 Ų041.9 Ų41.90%024%0.244CC..Hα-helixtrans-61.5-54.7-173.9-174.7-83.8000113.9L128 E163 I167 S168 I221 I245 I246 M247 Q270 C271 V272L128-F268 HydrophobicContact CD1-CE2 4.38Å; L128-F268 HydrophobicContact CD2-CE2 3.53Å; L128-F268 HydrophobicContact CD2-CZ 3.7Å; E163-F268 HydrophobicContact CB-CD1 3.71Å; E163-F268 HydrophobicContact CB-CE1 3.93Å; E163-F268 HydrophobicContact CB-CG 4.38Å; E163-F268 HydrophobicContact CG-CD1 3.52Å; E163-F268 HydrophobicContact CG-CE1 4.08Å; E163-F268 HydrophobicContact CG-CG 4.32Å; I167-F268 HydrophobicContact CB-CZ 4.4Å; I167-F268 HydrophobicContact CG2-CE1 4.47Å; I167-F268 HydrophobicContact CG2-CZ 3.97Å; S168-F268 WeakPolarHBondContact OG-CE2 3.38Å; I221-F268 HydrophobicContact CG2-CD2 3.91Å; I221-F268 HydrophobicContact CG2-CE2 4.08Å; I245-F268 HydrophobicContact CG2-CB 3.84Å; I245-F268 HydrophobicContact CG2-CD2 3.81Å; I245-F268 HydrophobicContact CG2-CG 4.26Å; I246-F268 WeakPolarHBondContact O-CB 3.39Å; I246-F268 PolarHBondContact O-N 2.89Å; M247-F268 HydrophobicContact CE-CE2 4.49Å; M247-F268 HydrophobicContact CG-CB 4.44Å; M247-F268 HydrophobicContact CG-CD2 4.14Å; M247-F268 HydrophobicContact CG-CG 4.3Å; F268-Q270 PolarHBondContact O-N 3.24Å; F268-C271 WeakPolarHBondContact O-CA 3.24Å; F268-C271 WeakPolarHBondContact O-CB 3.5Å; F268-C271 PolarHBondContact O-N 2.91Å; F268-V272 HydrophobicContact CD1-CG2 3.9Å; F268-V272 HydrophobicContact CE1-CG2 3.56Å; F268-V272 HydrophobicContact CZ-CG2 4.11Å; F268-V272 PolarHBondContact O-N 3.29Å
269D89.8Confident93.6Very high12 Ų1246.8 Ų46.86%0.06428%0.284CS..Hα-helixtrans-57-36.6-179.778.3-47.5000112.7E163 Q267 V272 R273E163-D269 PolarHBondContact OE1-N 3.16Å; Q267-D269 WeakPolarHBondContact CG-OD1 3.29Å; D269-V272 PolarHBondContact O-N 2.81Å; D269-R273 WeakPolarHBondContact O-CG 3.14Å; D269-R273 PolarHBondContact O-N 3.34Å; D269-R273 IonicContact OD2-CZ 3.11Å; D269-R273 IonicContact OD2-NH1 2.79Å; D269-R273 PolarHBondContact OD2-NH1 3.42Å; D269-R273 IonicContact OD2-NH2 2.73Å; D269-R273 PolarHBondContact OD2-NH2 3.06Å
270Q92.6Very high93.5Very high104 Ų10450.9 Ų50.949%0.48630%0.297SS..Hα-helixtrans-65.5-42.9174.8-64.2-177.80.900111.8Q267 F268 V272 R273 Q274Q267-Q270 HydrophobicContact CB-CB 4.24Å; Q267-Q270 HydrophobicContact CB-CG 4.03Å; Q267-Q270 HydrophobicContact CG-CG 4.06Å; Q267-Q270 PolarHBondContact O-N 3.25Å; F268-Q270 PolarHBondContact O-N 3.24Å; Q270-V272 VanDerWaalsContact C-N 3.34Å; Q270-V272 PolarHBondContact O-N 2.78Å; Q270-R273 PolarHBondContact O-N 3.3Å; Q270-Q274 VanDerWaalsContact O-CB 3.24Å; Q270-Q274 WeakPolarHBondContact O-CB 3.36Å; Q270-Q274 VanDerWaalsContact O-CG 3.24Å; Q270-Q274 WeakPolarHBondContact O-CG 3.27Å; Q270-Q274 PolarHBondContact O-N 3.4Å
271C94.9Very high93.5Very high1 Ų147.9 Ų47.91%0.00728%0.278CS..Hα-helixtrans-59.4-46.3175.8-63.20000110.8L128 Y131 I245 Q267 F268 G275L128-C271 HydrophobicContact CD1-CB 3.95Å; Y131-C271 WeakPolarHBondContact CB-O 3.38Å; Y131-C271 HydrophobicContact CD1-CB 3.47Å; Y131-C271 VanDerWaalsContact CD1-CB 3.47Å; Y131-C271 WeakPolarHBondContact CD2-O 3.39Å; Y131-C271 HydrophobicContact CE1-CB 3.75Å; Y131-C271 WeakPolarHBondContact CE1-SG 3.34Å; Y131-C271 HydrophobicContact CG-CB 3.91Å; I245-C271 HydrophobicContact CD1-CB 4.46Å; Q267-C271 PolarHBondContact O-N 3.32Å; Q267-C271 VanDerWaalsContact O-N 3.1Å; Q267-C271 PolarHBondContact O-SG 3.48Å; F268-C271 WeakPolarHBondContact O-CA 3.24Å; F268-C271 WeakPolarHBondContact O-CB 3.5Å; F268-C271 PolarHBondContact O-N 2.91Å; C271-G275 PolarHBondContact O-N 2.83Å
272V93.9Very high93.7Very high2 Ų250.2 Ų50.21%0.01229%0.294CS..Hα-helixtrans-60.5-54.9177.4178.40000110.8L128 V161 F268 D269 Q270 Q274 G275 C276L128-V272 HydrophobicContact CB-CG2 4.14Å; L128-V272 HydrophobicContact CD1-CG2 4.32Å; V161-V272 HydrophobicContact CG1-CB 4.12Å; V161-V272 HydrophobicContact CG1-CG1 3.77Å; V161-V272 HydrophobicContact CG1-CG2 4.38Å; F268-V272 HydrophobicContact CD1-CG2 3.9Å; F268-V272 HydrophobicContact CE1-CG2 3.56Å; F268-V272 HydrophobicContact CZ-CG2 4.11Å; F268-V272 PolarHBondContact O-N 3.29Å; D269-V272 PolarHBondContact O-N 2.81Å; Q270-V272 VanDerWaalsContact C-N 3.34Å; Q270-V272 PolarHBondContact O-N 2.78Å; V272-Q274 PolarHBondContact O-N 3.12Å; V272-G275 WeakPolarHBondContact O-CA 3.33Å; V272-G275 PolarHBondContact O-N 3.47Å; V272-C276 PolarHBondContact O-N 3.29Å; V272-C276 PolarHBondContact O-SG 3.24Å; V272-C276 VanDerWaalsContact O-SG 3.37Å
273R93Very high93.9Very high83 Ų8352.2 Ų52.231%0.31330%0.296SS..Hα-helixtrans-62-46.1-176.8-71.3-169.4-159.2111.925.8112.4F159 V161 D269 Q270 G275 C276 T277F159-R273 PolarHBondContact O-NH2 3.08Å; V161-R273 HydrophobicContact CG2-CG 4.08Å; D269-R273 WeakPolarHBondContact O-CG 3.14Å; D269-R273 PolarHBondContact O-N 3.34Å; D269-R273 IonicContact OD2-CZ 3.11Å; D269-R273 IonicContact OD2-NH1 2.79Å; D269-R273 PolarHBondContact OD2-NH1 3.42Å; D269-R273 IonicContact OD2-NH2 2.73Å; D269-R273 PolarHBondContact OD2-NH2 3.06Å; Q270-R273 PolarHBondContact O-N 3.3Å; R273-G275 VanDerWaalsContact C-N 3.29Å; R273-G275 PolarHBondContact O-N 3.39Å; R273-C276 PolarHBondContact O-N 2.89Å; R273-T277 PolarHBondContact O-N 3.03Å
274Q95.2Very high94.1Very high89 Ų8954.8 Ų54.842%0.41631%0.313SS..Hα-helixtrans-61.9-43.1176.9-71.9177.4-3.800110.1Y131 Q270 V272 C276 T277 I278Y131-Q274 HydrophobicContact CD2-CB 3.89Å; Y131-Q274 HydrophobicContact CE2-CB 3.65Å; Y131-Q274 HydrophobicContact CE2-CG 4.48Å; Y131-Q274 PolarHBondContact OH-OE1 2.87Å; Q270-Q274 VanDerWaalsContact O-CB 3.24Å; Q270-Q274 WeakPolarHBondContact O-CB 3.36Å; Q270-Q274 VanDerWaalsContact O-CG 3.24Å; Q270-Q274 WeakPolarHBondContact O-CG 3.27Å; Q270-Q274 PolarHBondContact O-N 3.4Å; V272-Q274 PolarHBondContact O-N 3.12Å; Q274-C276 PolarHBondContact O-N 3.43Å; Q274-T277 PolarHBondContact O-N 2.83Å; Q274-T277 PolarHBondContact O-OG1 3.3Å; Q274-I278 WeakPolarHBondContact O-CG1 3.45Å; Q274-I278 PolarHBondContact O-N 3.4Å
275G96.4Very high94.2Very high0 Ų053.4 Ų53.40%031%0.314CS..Hα-helixtrans-55.9-42.7174.700000114.5G127 K130 C271 V272 R273 T277 I278G127-G275 WeakPolarHBondContact O-CA 3.26Å; K130-G275 WeakPolarHBondContact CD-O 3.08Å; C271-G275 PolarHBondContact O-N 2.83Å; V272-G275 WeakPolarHBondContact O-CA 3.33Å; V272-G275 PolarHBondContact O-N 3.47Å; R273-G275 VanDerWaalsContact C-N 3.29Å; R273-G275 PolarHBondContact O-N 3.39Å; G275-T277 PolarHBondContact O-N 3.47Å; G275-I278 PolarHBondContact O-N 2.79Å
276C94.3Very high94.2Very high53 Ų5355.6 Ų55.636%0.35833%0.329SS..Hα-helixtrans-63-23175.2-66.60000113.4V272 R273 Q274V272-C276 PolarHBondContact O-N 3.29Å; V272-C276 PolarHBondContact O-SG 3.24Å; V272-C276 VanDerWaalsContact O-SG 3.37Å; R273-C276 PolarHBondContact O-N 2.89Å; Q274-C276 PolarHBondContact O-N 3.43Å
277T95.7Very high94.3Very high114 Ų11455 Ų5570%0.69933%0.326SS*.THydrogen-bonded Turntrans-89.4-6.9178.666.50000114.4R273 Q274 G275 A279R273-T277 PolarHBondContact O-N 3.03Å; Q274-T277 PolarHBondContact O-N 2.83Å; Q274-T277 PolarHBondContact O-OG1 3.3Å; G275-T277 PolarHBondContact O-N 3.47Å; T277-A279 PolarHBondContact O-N 3.44Å
278I95.6Very high94.5Very high30 Ų3060.7 Ų60.715%0.15435%0.353CS..  trans-74.8109.6179.7-58.5174.4000109.3K130 H134 Q274 G275 D280 A281K130-I278 HydrophobicContact CB-CD1 4.26Å; H134-I278 HydrophobicContact CB-CD1 3.72Å; Q274-I278 WeakPolarHBondContact O-CG1 3.45Å; Q274-I278 PolarHBondContact O-N 3.4Å; G275-I278 PolarHBondContact O-N 2.79Å; I278-D280 WeakPolarHBondContact CG2-OD1 3.42Å; I278-A281 HydrophobicContact CG2-CB 3.86Å
279A91.3Very high94.8Very high102 Ų10262.1 Ų62.184%0.84336%0.362SS*.SBendtrans-89.2-24.2-176.900000113.9T277T277-A279 PolarHBondContact O-N 3.44Å
280D92.3Very high95.2Very high151 Ų15167.6 Ų67.681%0.80739%0.391SS*.SBendtrans-99.812.2-17562.9-32.8000113.7I278I278-D280 WeakPolarHBondContact CG2-OD1 3.42Å
281A91.6Very high95.4Very high28 Ų2864.7 Ų64.723%0.23138%0.379CS..PPolyproline II helixtrans-64.7143.7173.400000111.2K130 I278K130-A281 HydrophobicContact CB-CB 4.26Å; K130-A281 HydrophobicContact CD-CB 4.09Å; K130-A281 HydrophobicContact CG-CB 3.75Å; I278-A281 HydrophobicContact CG2-CB 3.86Å
282P93.9Very high95.6Very high70 Ų7065.4 Ų65.446%0.45538%0.383SS..PPolyproline II helixtrans-61.7155.4173.927.7-34.9000111.1L133 Y175L133-P282 HydrophobicContact CD1-CG 3.53Å; Y175-P282 HydrophobicContact CE1-CG 4.12Å; Y175-P282 PolarHBondContact OH-O 2.68Å
283P94.5Very high95.7Very high100 Ų10065.3 Ų65.365%0.64938%0.382SS*.PPolyproline II helixtrans-59.2147.4176.826.2-34.5000111.2Y175 T285Y175-P283 WeakPolarHBondContact CE1-O 3.34Å; P283-T285 PolarHBondContact O-N 3.05Å; P283-T285 PolarHBondContact O-OG1 3Å
284P95.8Very high95.9Very high57 Ų5761.4 Ų61.437%0.3737%0.367SS..PPolyproline II helixtrans-49.1137.3173.5-2936.3000111.8V174 P286V174-P284 HydrophobicContact CG1-CB 3.98Å; V174-P284 HydrophobicContact CG1-CG 4.2Å; P284-P286 WeakPolarHBondContact O-CD 3.42Å
285T97.2Very high95.8Very high81 Ų8157.2 Ų57.250%0.49735%0.348SS..  trans-120.383.4176.5-52.70000106.8V174 Y175 S176 P283V174-T285 CarbonylContact O-C 3.41Å; V174-T285 PolarHBondContact O-N 3.12Å; Y175-T285 CarbonylContact C-O 3.45Å; Y175-T285 WeakPolarHBondContact CA-O 3.43Å; S176-T285 PolarHBondContact N-O 2.73Å; S176-T285 PolarHBondContact OG-O 2.88Å; P283-T285 PolarHBondContact O-N 3.05Å; P283-T285 PolarHBondContact O-OG1 3Å
286P97.2Very high95.5Very high58 Ų5857.3 Ų57.338%0.37735%0.349SS..PPolyproline II helixtrans-66.8156.5-175.529.8-36000111.7Y84 S176 P284Y84-P286 HydrophobicContact CD1-CB 3.69Å; Y84-P286 HydrophobicContact CD2-CB 4.4Å; Y84-P286 HydrophobicContact CE1-CB 3.46Å; Y84-P286 VanDerWaalsContact CE1-CB 3.46Å; Y84-P286 HydrophobicContact CE1-CG 4.28Å; Y84-P286 HydrophobicContact CE2-CB 4.2Å; Y84-P286 HydrophobicContact CG-CB 4.15Å; S176-P286 PolarHBondContact OG-O 3.47Å; P284-P286 WeakPolarHBondContact O-CD 3.42Å
287P98.1Very high95.1Very high8 Ų855.5 Ų55.55%0.05233%0.334CS..PPolyproline II helixtrans-72.8154.1-177.630.8-36.4000111.3T82 Y173 S176 D291 H312T82-P287 HydrophobicContact CG2-CG 4.36Å; T82-P287 WeakPolarHBondContact CG2-O 3.44Å; Y173-P287 VanDerWaalsContact O-CD 3.25Å; Y173-P287 WeakPolarHBondContact O-CD 3.4Å; S176-P287 VanDerWaalsContact OG-CA 3.29Å; S176-P287 WeakPolarHBondContact OG-CA 3.37Å; P287-D291 HydrophobicContact CB-CB 4.08Å; P287-H312 VanDerWaalsContact CB-CD2 3.48Å; P287-H312 WeakPolarHBondContact CB-CD2 3.34Å; P287-H312 WeakPolarHBondContact CB-NE2 3.34Å; P287-H312 VanDerWaalsContact CG-NE2 3.28Å; P287-H312 WeakPolarHBondContact CG-NE2 3.33Å
288E98.4Very high94.1Very high132 Ų13251 Ų5162%0.61731%0.307SS*.PPolyproline II helixtrans-85.5162.6165.9-67.1-63.3154.200110.7D290 D291E288-D290 VanDerWaalsContact C-N 3.28Å; E288-D290 PolarHBondContact O-N 3.14Å; E288-D291 PolarHBondContact N-OD2 3.48Å; E288-D291 VanDerWaalsContact O-CB 3.32Å; E288-D291 WeakPolarHBondContact O-CB 3.1Å; E288-D291 PolarHBondContact O-N 3.3Å; E288-D291 VanDerWaalsContact O-N 3.12Å
289P98.5Very high92.5Very high30 Ų3050.8 Ų50.820%0.19531%0.308CS..THydrogen-bonded Turntrans-58.3-35.3-177.3-27.437.4000114.6R81 T82 D291 H312 A313R81-P289 HydrophobicContact CB-CG 3.8Å; T82-P289 HydrophobicContact CG2-CG 4.41Å; P289-D291 VanDerWaalsContact C-N 3.31Å; P289-H312 PolarHBondContact O-N 3.13Å; P289-A313 HydrophobicContact CB-CB 3.96Å; P289-A313 VanDerWaalsContact O-CB 3.24Å; P289-A313 WeakPolarHBondContact O-CB 3.39Å; P289-A313 PolarHBondContact O-N 2.69Å
290D97.9Very high90.6Very high126 Ų12647 Ų4767%0.67428%0.279SS*.THydrogen-bonded Turntrans-85-4.5-178.5-67.9-26.1000113.7E288 T311E288-D290 VanDerWaalsContact C-N 3.28Å; E288-D290 PolarHBondContact O-N 3.14Å; D290-T311 WeakPolarHBondContact O-CG2 3.2Å
291D98.4Very high88.4Confident43 Ų4341.8 Ų41.823%0.2325%0.253CS..SBendtrans-68.4145.9173.1-74.4-24.6000110.6Q141 P287 E288 P289 C293 T311 H312Q141-D291 HydrophobicContact CG-CB 4.22Å; P287-D291 HydrophobicContact CB-CB 4.08Å; E288-D291 PolarHBondContact N-OD2 3.48Å; E288-D291 VanDerWaalsContact O-CB 3.32Å; E288-D291 WeakPolarHBondContact O-CB 3.1Å; E288-D291 PolarHBondContact O-N 3.3Å; E288-D291 VanDerWaalsContact O-N 3.12Å; P289-D291 VanDerWaalsContact C-N 3.31Å; D291-C293 PolarHBondContact O-N 2.87Å; D291-T311 CarbonylContact O-C 3.6Å; D291-T311 WeakPolarHBondContact O-CA 3.21Å; D291-T311 WeakPolarHBondContact O-CB 3.21Å; D291-H312 PolarHBondContact O-CD2 3.44Å; D291-H312 PolarHBondContact O-N 2.77Å
292L97.7Very high86.4Confident17 Ų1744.8 Ų44.89%0.08927%0.268CS..EExtended strand (participates in β ladder)trans-62123.6172.1-65.5-177.5000109.7Q141 V178 M309 T311 K538Q141-L292 PolarHBondContact NE2-O 3.23Å; V178-L292 HydrophobicContact CG1-CB 4.02Å; V178-L292 HydrophobicContact CG2-CB 3.76Å; L292-M309 HydrophobicContact CD1-SD 4.33Å; L292-M309 HydrophobicContact CD2-CB 3.79Å; L292-M309 HydrophobicContact CD2-CG 4.43Å; L292-T311 HydrophobicContact CD2-CG2 4.31Å; L292-K538 HydrophobicContact CD2-CD 4.31Å
293C97.4Very high84.6Confident0 Ų047 Ų470%028%0.277CS..EExtended strand (participates in β ladder)trans-85.6-43.6170.6178.90000110Y173 N179 D291 L310 H312 I315Y173-C293 WeakPolarHBondContact CE1-O 3.44Å; Y173-C293 VanDerWaalsContact CE1-SG 3.6Å; Y173-C293 PolarHBondContact OH-SG 3.02Å; N179-C293 PolarHBondContact ND2-O 3.44Å; D291-C293 PolarHBondContact O-N 2.87Å; C293-L310 PolarHBondContact N-O 3.33Å; C293-H312 HydrophobicContact CB-CB 4.42Å; C293-H312 VanDerWaalsContact SG-CE1 3.53Å; C293-I315 HydrophobicContact CB-CD1 3.8Å; C293-I315 VanDerWaalsContact SG-CD1 3.5Å
294T95.7Very high83.4Confident0 Ų050.8 Ų50.80%028%0.278CS..EExtended strand (participates in β ladder)trans-157.1153.7-174.5-168.80000112.8N179 P181 L310 I315 M345 R348N179-T294 VanDerWaalsContact O-CA 3.28Å; N179-T294 WeakPolarHBondContact O-CA 3.46Å; N179-T294 PolarHBondContact O-OG1 3.48Å; N179-T294 WeakPolarHBondContact OD1-CB 3.45Å; N179-T294 PolarHBondContact OD1-OG1 2.67Å; P181-T294 WeakPolarHBondContact CD-OG1 3.37Å; T294-L310 HydrophobicContact CG2-CB 3.91Å; T294-L310 HydrophobicContact CG2-CD1 4.15Å; T294-L310 PolarHBondContact N-O 3.04Å; T294-L310 PolarHBondContact O-N 3.36Å; T294-I315 HydrophobicContact CG2-CD1 4.23Å; T294-M345 HydrophobicContact CG2-SD 4.29Å; T294-R348 PolarHBondContact OG1-NH1 3.28Å
295V94.4Very high82.5Confident1 Ų148.8 Ų48.81%0.00627%0.265CS..EExtended strand (participates in β ladder)trans-114.7100.3166.9-176.40000109.5F144 V178 N179 V180 P181 Y297 V308 M309 Y541F144-V295 HydrophobicContact CD1-CG2 4.24Å; F144-V295 HydrophobicContact CE1-CG2 3.77Å; V178-V295 HydrophobicContact CG1-CG2 4.04Å; N179-V295 PolarHBondContact O-N 3.04Å; N179-V295 VanDerWaalsContact O-N 3.08Å; V180-V295 HydrophobicContact CG2-CB 4.34Å; P181-V295 WeakPolarHBondContact CD-O 3.35Å; V295-Y297 HydrophobicContact CG1-CD2 4.35Å; V295-Y297 HydrophobicContact CG1-CE2 3.75Å; V295-V308 WeakPolarHBondContact CA-O 3.37Å; V295-M309 HydrophobicContact CG2-CG 4.36Å; V295-Y541 HydrophobicContact CG1-CD2 4.47Å; V295-Y541 HydrophobicContact CG1-CG 4.11Å; V295-Y541 HydrophobicContact CG2-CD2 4.21Å
296C89.6Confident82Confident3 Ų347.5 Ų47.52%0.0225%0.252CS..EExtended strand (participates in β ladder)trans-92119-177-74.10000111.2T298 V308 M345 T482C296-T298 PolarHBondContact O-N 3.42Å; C296-V308 PolarHBondContact N-O 3.39Å; C296-V308 WeakPolarHBondContact O-CB 3.21Å; C296-V308 PolarHBondContact O-N 3.48Å; C296-M345 PolarHBondContact SG-SD 2.96Å; C296-T482 HydrophobicContact CB-CG2 3.55Å
297Y85.1Confident81.7Confident14 Ų1444.7 Ų44.76%0.05523%0.234CC..EExtended strand (participates in β ladder)trans-84.3120.3-179.4-77.2-96.4000112.8V180 Y183 I194 Q197 V295 P305 K306V180-Y297 HydrophobicContact CG1-CD2 3.92Å; V180-Y297 HydrophobicContact CG1-CE2 3.61Å; Y183-Y297 VanDerWaalsContact CE1-O 3.31Å; Y183-Y297 WeakPolarHBondContact CE1-O 3.43Å; Y183-Y297 PolarHBondContact OH-O 2.95Å; Y183-Y297 VanDerWaalsContact OH-O 3.13Å; I194-Y297 HydrophobicContact CB-CE1 4.48Å; I194-Y297 HydrophobicContact CB-CE2 4.39Å; I194-Y297 HydrophobicContact CD1-CD1 3.96Å; I194-Y297 HydrophobicContact CD1-CD2 4.01Å; I194-Y297 HydrophobicContact CD1-CG 3.62Å; I194-Y297 HydrophobicContact CG1-CD1 3.63Å; I194-Y297 HydrophobicContact CG1-CD2 4.05Å; I194-Y297 HydrophobicContact CG1-CE1 3.78Å; I194-Y297 HydrophobicContact CG1-CE2 4.21Å; I194-Y297 HydrophobicContact CG1-CG 3.75Å; I194-Y297 HydrophobicContact CG2-CD2 3.76Å; I194-Y297 HydrophobicContact CG2-CE1 4.28Å; I194-Y297 HydrophobicContact CG2-CE2 3.39Å; I194-Y297 HydrophobicContact CG2-CG 4.34Å; Q197-Y297 PolarHBondContact OE1-OH 2.88Å; V295-Y297 HydrophobicContact CG1-CD2 4.35Å; V295-Y297 HydrophobicContact CG1-CE2 3.75Å; Y297-P305 HydrophobicContact CD1-CB 3.92Å; Y297-K306 WeakPolarHBondContact CA-O 3.05Å
298T75.5Confident81.5Confident20 Ų2044.3 Ų44.312%0.12323%0.232CC..PPolyproline II helixtrans-70.5145.1173.755.20000110.9C296 G300 P305 K306 V308C296-T298 PolarHBondContact O-N 3.42Å; T298-G300 PolarHBondContact O-N 2.76Å; T298-G300 VanDerWaalsContact O-N 3.08Å; T298-P305 WeakPolarHBondContact O-CA 3.29Å; T298-P305 WeakPolarHBondContact O-CB 3.33Å; T298-K306 PolarHBondContact N-O 2.98Å; T298-K306 PolarHBondContact OG1-O 3.34Å; T298-V308 HydrophobicContact CG2-CG2 3.64Å
299S61.7Low81.4Confident25 Ų2539.5 Ų39.518%0.17521%0.21CC..  trans-71.3104.717047.60000108.2Y183 T301 T695Y183-S299 WeakPolarHBondContact OH-CA 3.32Å; Y183-S299 PolarHBondContact OH-N 3.04Å; S299-T301 PolarHBondContact O-N 3.11Å; S299-T695 PolarHBondContact OG-OG1 2.89Å; S299-T695 VanDerWaalsContact OG-OG1 3.11Å
300G51.5Low81.4Confident23 Ų2338.1 Ų38.124%0.23720%0.2CC..  trans-59.7107.1172.900000109.2T298 T302 D303T298-G300 PolarHBondContact O-N 2.76Å; T298-G300 VanDerWaalsContact O-N 3.08Å; G300-T302 PolarHBondContact O-N 3.14Å; G300-D303 WeakPolarHBondContact CA-O 3.48Å
301T47.4Very low81.4Confident42 Ų4232.6 Ų32.626%0.25817%0.171SC..SBendtrans-67.3-22.1173.449.60000111.3S299 T693S299-T301 PolarHBondContact O-N 3.11Å; T301-T693 HydrophobicContact CG2-CG2 3.67Å
302T49.1Very low81.5Confident91 Ų9130.6 Ų30.656%0.55816%0.161SC*.SBendtrans-138-20.1-171.141.50000114.2G300 P701G300-T302 PolarHBondContact O-N 3.14Å; T302-P701 HydrophobicContact CG2-CG 4.37Å
303D56.1Low81.5Confident117 Ų11731 Ų3163%0.62617%0.167SC*.SBendtrans-135.7-177.2-174.6-80.2-43.2000112.4G300G300-D303 WeakPolarHBondContact CA-O 3.48Å
304R69.2Low81.6Confident178 Ų17831.7 Ų31.767%0.67217%0.17SC*.SBendtrans-56.3148.6169.2-66.6179.3178.5168.2-1.3111Y193 K306Y193-R304 HydrophobicContact CE1-CB 4.08Å; R304-K306 PolarHBondContact O-N 3.12Å
305P77.2Confident81.7Confident16 Ų1631.7 Ų31.710%0.10417%0.17CC..PPolyproline II helixtrans-54.8134.7175.4-23.832.6000112.1L186 A190 Y193 I194 Y297 T298L186-P305 HydrophobicContact CD2-CG 4.49Å; A190-P305 HydrophobicContact CB-CG 3.85Å; Y193-P305 HydrophobicContact CD1-CG 4.48Å; Y193-P305 WeakPolarHBondContact CE1-O 3.4Å; I194-P305 HydrophobicContact CD1-CB 4.48Å; Y297-P305 HydrophobicContact CD1-CB 3.92Å; T298-P305 WeakPolarHBondContact O-CA 3.29Å; T298-P305 WeakPolarHBondContact O-CB 3.33Å
306K85.6Confident81.9Confident53 Ų5331.7 Ų31.723%0.2317%0.17CC..PPolyproline II helixtrans-103.3127.3177.3-60.2177.4-75.3164.80109.8Y297 T298 R304 Y540Y297-K306 WeakPolarHBondContact CA-O 3.05Å; T298-K306 PolarHBondContact N-O 2.98Å; T298-K306 PolarHBondContact OG1-O 3.34Å; R304-K306 PolarHBondContact O-N 3.12Å; K306-Y540 HydrophobicContact CB-CD1 3.68Å; K306-Y540 HydrophobicContact CB-CE1 3.93Å; K306-Y540 HydrophobicContact CB-CG 4.26Å; K306-Y540 HydrophobicContact CD-CD1 4.32Å; K306-Y540 HydrophobicContact CD-CD2 4.38Å; K306-Y540 HydrophobicContact CD-CE1 4.15Å; K306-Y540 HydrophobicContact CD-CE2 4.19Å; K306-Y540 HydrophobicContact CD-CG 4.43Å; K306-Y540 PolarHBondContact NZ-OH 2.75Å
307G90.5Very high82.3Confident0 Ų031.6 Ų31.60%017%0.17CC..EExtended strand (participates in β ladder)trans-79.1115.9177.900000111.2Y540 Y541G307-Y540 CarbonylContact O-C 3.56Å; G307-Y540 VanDerWaalsContact O-CA 3.26Å; G307-Y540 WeakPolarHBondContact O-CA 3.33Å; G307-Y541 WeakPolarHBondContact O-CB 3.4Å; G307-Y541 PolarHBondContact O-N 3.15Å
308V93.9Very high82.9Confident0 Ų031 Ų310%017%0.167CC..EExtended strand (participates in β ladder)trans-87.1115.6178178.50000108.6V295 C296 T298 L310 T482 E483 F537 Y540V295-V308 WeakPolarHBondContact CA-O 3.37Å; C296-V308 PolarHBondContact N-O 3.39Å; C296-V308 WeakPolarHBondContact O-CB 3.21Å; C296-V308 PolarHBondContact O-N 3.48Å; T298-V308 HydrophobicContact CG2-CG2 3.64Å; V308-L310 HydrophobicContact CG1-CD1 4.49Å; V308-L310 HydrophobicContact CG1-CD2 3.96Å; V308-L310 HydrophobicContact CG1-CG 3.99Å; V308-L310 PolarHBondContact O-N 3.28Å; V308-T482 HydrophobicContact CB-CG2 3.89Å; V308-T482 HydrophobicContact CG1-CG2 4.04Å; V308-T482 HydrophobicContact CG2-CG2 3.89Å; V308-E483 HydrophobicContact CG1-CG 4.35Å; V308-E483 HydrophobicContact CG2-CG 4.04Å; V308-F537 HydrophobicContact CB-CD2 4.27Å; V308-F537 HydrophobicContact CG1-CB 3.68Å; V308-F537 HydrophobicContact CG1-CD2 3.45Å; V308-F537 VanDerWaalsContact CG1-CD2 3.45Å; V308-F537 HydrophobicContact CG1-CE2 4.38Å; V308-F537 HydrophobicContact CG1-CG 3.91Å; V308-Y540 HydrophobicContact CG2-CD1 4.19Å; V308-Y540 HydrophobicContact CG2-CE1 3.92Å
309M97.5Very high84Confident31 Ų3130 Ų3015%0.15316%0.161CC..EExtended strand (participates in β ladder)trans-83.2109.4179.3-66.7-173.3-66.900111.2L292 V295 F537 K538 G539 Y541L292-M309 HydrophobicContact CD1-SD 4.33Å; L292-M309 HydrophobicContact CD2-CB 3.79Å; L292-M309 HydrophobicContact CD2-CG 4.43Å; V295-M309 HydrophobicContact CG2-CG 4.36Å; M309-F537 WeakPolarHBondContact O-CB 3.36Å; M309-K538 HydrophobicContact CB-CB 4.19Å; M309-K538 PolarHBondContact O-N 2.63Å; M309-G539 WeakPolarHBondContact CB-O 3.37Å; M309-G539 PolarHBondContact N-O 2.88Å; M309-Y541 HydrophobicContact CG-CD2 3.87Å; M309-Y541 HydrophobicContact CG-CG 4.45Å; M309-Y541 HydrophobicContact SD-CD2 3.69Å; M309-Y541 HydrophobicContact SD-CE2 4.48Å
310L98.4Very high85.7Confident0 Ų028.8 Ų28.80%015%0.153CC..EExtended strand (participates in β ladder)trans-111.7126.3179-63.2174.5000110.4C293 T294 V308 I315 M345 V485 F537C293-L310 PolarHBondContact N-O 3.33Å; T294-L310 HydrophobicContact CG2-CB 3.91Å; T294-L310 HydrophobicContact CG2-CD1 4.15Å; T294-L310 PolarHBondContact N-O 3.04Å; T294-L310 PolarHBondContact O-N 3.36Å; V308-L310 HydrophobicContact CG1-CD1 4.49Å; V308-L310 HydrophobicContact CG1-CD2 3.96Å; V308-L310 HydrophobicContact CG1-CG 3.99Å; V308-L310 PolarHBondContact O-N 3.28Å; L310-I315 HydrophobicContact CB-CD1 4.42Å; L310-I315 HydrophobicContact CB-CG1 4.47Å; L310-M345 HydrophobicContact CD1-CE 3.81Å; L310-M345 HydrophobicContact CD1-CG 3.81Å; L310-M345 HydrophobicContact CD1-SD 3.75Å; L310-V485 HydrophobicContact CD1-CG2 4.25Å; L310-V485 HydrophobicContact CD2-CG2 3.86Å; L310-F537 HydrophobicContact CD2-CB 3.57Å
311T98.7Very high87.8Confident10 Ų1028.3 Ų28.36%0.06115%0.145CC..EExtended strand (participates in β ladder)trans-81.2165.5174.269.20000111.5D290 D291 L292 A313 N314 I315D290-T311 WeakPolarHBondContact O-CG2 3.2Å; D291-T311 CarbonylContact O-C 3.6Å; D291-T311 WeakPolarHBondContact O-CA 3.21Å; D291-T311 WeakPolarHBondContact O-CB 3.21Å; L292-T311 HydrophobicContact CD2-CG2 4.31Å; T311-A313 VanDerWaalsContact C-N 3.31Å; T311-A313 PolarHBondContact O-N 3.25Å; T311-N314 PolarHBondContact N-OD1 2.87Å; T311-N314 PolarHBondContact O-N 3.4Å; T311-N314 PolarHBondContact OG1-N 2.89Å; T311-N314 VanDerWaalsContact OG1-N 3.07Å; T311-N314 PolarHBondContact OG1-OD1 3.03Å; T311-I315 PolarHBondContact O-N 3.44Å
312H98.6Very high90Very high1 Ų126.9 Ų26.91%0.00514%0.136CC..Hα-helixtrans-59.5-42.2171.5-80.5-73.6000112.2T82 V83 Y173 P287 P289 D291 C293 N314 I315 V316T82-H312 HydrophobicContact CG2-CB 3.89Å; V83-H312 PolarHBondContact N-ND1 2.9Å; Y173-H312 AromaticContact CD1-CE1 3.56Å; Y173-H312 AromaticContact CD1-NE2 3.84Å; Y173-H312 AromaticContact CE1-CE1 3.72Å; Y173-H312 AromaticContact CG-CE1 3.93Å; P287-H312 VanDerWaalsContact CB-CD2 3.48Å; P287-H312 WeakPolarHBondContact CB-CD2 3.34Å; P287-H312 WeakPolarHBondContact CB-NE2 3.34Å; P287-H312 VanDerWaalsContact CG-NE2 3.28Å; P287-H312 WeakPolarHBondContact CG-NE2 3.33Å; P289-H312 PolarHBondContact O-N 3.13Å; D291-H312 PolarHBondContact O-CD2 3.44Å; D291-H312 PolarHBondContact O-N 2.77Å; C293-H312 HydrophobicContact CB-CB 4.42Å; C293-H312 VanDerWaalsContact SG-CE1 3.53Å; H312-N314 VanDerWaalsContact C-N 3.34Å; H312-N314 PolarHBondContact O-N 2.81Å; H312-I315 PolarHBondContact O-N 2.56Å; H312-V316 WeakPolarHBondContact O-CG2 3.17Å; H312-V316 PolarHBondContact O-N 2.83Å
313A98.6Very high92.2Very high26 Ų2623.8 Ų23.822%0.21512%0.118CC..Hα-helixtrans-62.4-38.9176.200000112.1P289 T311 I315 V316 A317P289-A313 HydrophobicContact CB-CB 3.96Å; P289-A313 VanDerWaalsContact O-CB 3.24Å; P289-A313 WeakPolarHBondContact O-CB 3.39Å; P289-A313 PolarHBondContact O-N 2.69Å; T311-A313 VanDerWaalsContact C-N 3.31Å; T311-A313 PolarHBondContact O-N 3.25Å; A313-I315 VanDerWaalsContact C-N 3.31Å; A313-I315 PolarHBondContact O-N 2.98Å; A313-V316 PolarHBondContact O-N 2.97Å; A313-A317 VanDerWaalsContact O-CB 3.24Å; A313-A317 WeakPolarHBondContact O-CB 3.4Å; A313-A317 PolarHBondContact O-N 3.2Å
314N98.6Very high93.9Very high14 Ų1418.5 Ų18.58%0.0759%0.091CC..Hα-helixtrans-56.1-49.3176.8-64.6149.5000111.1T311 H312 A317 D318 V485 P534 N535 V536T311-N314 PolarHBondContact N-OD1 2.87Å; T311-N314 PolarHBondContact O-N 3.4Å; T311-N314 PolarHBondContact OG1-N 2.89Å; T311-N314 VanDerWaalsContact OG1-N 3.07Å; T311-N314 PolarHBondContact OG1-OD1 3.03Å; H312-N314 VanDerWaalsContact C-N 3.34Å; H312-N314 PolarHBondContact O-N 2.81Å; N314-A317 PolarHBondContact O-N 3.08Å; N314-D318 PolarHBondContact O-N 3.44Å; N314-V485 HydrophobicContact CB-CG2 3.84Å; N314-P534 VanDerWaalsContact CA-O 3.28Å; N314-P534 WeakPolarHBondContact CA-O 3.12Å; N314-P534 PolarHBondContact ND2-O 3.29Å; N314-N535 WeakPolarHBondContact O-CA 3.26Å; N314-V536 PolarHBondContact ND2-O 3.41Å
315I98.5Very high95Very high0 Ų010.5 Ų10.50%06%0.061CC..Hα-helixtrans-71.3-41.5-175.1-62.5169.9000111.3V83 C293 T294 L310 T311 H312 A313 A317 D318 G319 M345 I352 V485V83-I315 HydrophobicContact CG2-CB 4.09Å; V83-I315 HydrophobicContact CG2-CD1 4.23Å; V83-I315 HydrophobicContact CG2-CG2 3.85Å; C293-I315 HydrophobicContact CB-CD1 3.8Å; C293-I315 VanDerWaalsContact SG-CD1 3.5Å; T294-I315 HydrophobicContact CG2-CD1 4.23Å; L310-I315 HydrophobicContact CB-CD1 4.42Å; L310-I315 HydrophobicContact CB-CG1 4.47Å; T311-I315 PolarHBondContact O-N 3.44Å; H312-I315 PolarHBondContact O-N 2.56Å; A313-I315 VanDerWaalsContact C-N 3.31Å; A313-I315 PolarHBondContact O-N 2.98Å; I315-A317 VanDerWaalsContact C-N 3.32Å; I315-A317 PolarHBondContact O-N 3.44Å; I315-D318 PolarHBondContact O-N 2.93Å; I315-G319 PolarHBondContact O-N 2.92Å; I315-M345 HydrophobicContact CD1-CE 3.86Å; I315-M345 HydrophobicContact CG1-CE 3.89Å; I315-I352 HydrophobicContact CG2-CD1 3.4Å; I315-I352 HydrophobicContact CG2-CG2 4.37Å; I315-V485 HydrophobicContact CG1-CG1 4.18Å; I315-V485 HydrophobicContact CG1-CG2 3.93Å
316V98.5Very high95.4Very high2 Ų213.1 Ų13.11%0.0128%0.078CC..Hα-helixtrans-64.4-38.9177.11690000111.4F75 V80 H312 A313 G319F75-V316 HydrophobicContact CB-CG1 3.68Å; V80-V316 HydrophobicContact CG1-CG2 4.46Å; V80-V316 WeakPolarHBondContact O-CG1 3.46Å; H312-V316 WeakPolarHBondContact O-CG2 3.17Å; H312-V316 PolarHBondContact O-N 2.83Å; A313-V316 PolarHBondContact O-N 2.97Å; V316-G319 PolarHBondContact O-N 2.78Å
317A98.6Very high95.5Very high1 Ų112.5 Ų12.51%0.0088%0.083CC..Hα-helixtrans-63.7-47.2174.700000111.3L74 A313 N314 I315 G319 T320 A507 P534L74-A317 VanDerWaalsContact O-CA 3.24Å; L74-A317 WeakPolarHBondContact O-CA 3.32Å; L74-A317 WeakPolarHBondContact O-CB 3.33Å; L74-A317 PolarHBondContact O-N 3.03Å; A313-A317 VanDerWaalsContact O-CB 3.24Å; A313-A317 WeakPolarHBondContact O-CB 3.4Å; A313-A317 PolarHBondContact O-N 3.2Å; N314-A317 PolarHBondContact O-N 3.08Å; I315-A317 VanDerWaalsContact C-N 3.32Å; I315-A317 PolarHBondContact O-N 3.44Å; A317-G319 PolarHBondContact O-N 3.21Å; A317-T320 VanDerWaalsContact O-CB 3.24Å; A317-T320 WeakPolarHBondContact O-CB 3.45Å; A317-T320 WeakPolarHBondContact O-CG2 3.47Å; A317-T320 PolarHBondContact O-N 3.44Å; A317-T320 PolarHBondContact O-OG1 2.86Å; A317-A507 HydrophobicContact CB-CB 4.14Å; A317-A507 VanDerWaalsContact O-CB 3.26Å; A317-A507 WeakPolarHBondContact O-CB 3.15Å; A317-P534 HydrophobicContact CB-CB 3.71Å; A317-P534 HydrophobicContact CB-CG 3.69Å
318D98.4Very high95.5Very high0 Ų015.1 Ų15.10%010%0.095CC..Hα-helixtrans-61.3-31.2177.4-152.225.6000112N314 I315 T320 V321 L349 V485 A486 A487 N535N314-D318 PolarHBondContact O-N 3.44Å; I315-D318 PolarHBondContact O-N 2.93Å; D318-T320 PolarHBondContact O-N 2.72Å; D318-V321 WeakPolarHBondContact O-CB 3.39Å; D318-V321 VanDerWaalsContact O-CG1 3.22Å; D318-V321 WeakPolarHBondContact O-CG1 3.46Å; D318-V321 PolarHBondContact O-N 3.12Å; D318-L349 HydrophobicContact CB-CD1 3.95Å; D318-L349 HydrophobicContact CB-CD2 4.44Å; D318-L349 WeakPolarHBondContact OD2-CD2 3.34Å; D318-V485 HydrophobicContact CB-CB 3.81Å; D318-V485 HydrophobicContact CB-CG1 3.73Å; D318-V485 HydrophobicContact CB-CG2 4.33Å; D318-V485 VanDerWaalsContact OD2-CB 3.26Å; D318-V485 WeakPolarHBondContact OD2-CB 3.37Å; D318-V485 VanDerWaalsContact OD2-CG1 3.25Å; D318-V485 WeakPolarHBondContact OD2-CG1 3.36Å; D318-A486 PolarHBondContact OD2-N 2.89Å; D318-A487 PolarHBondContact OD2-N 3.24Å; D318-N535 HydrophobicContact CB-CB 3.83Å
319G97.4Very high95.4Very high0 Ų018 Ų180%011%0.114CC..G310 helixtrans-58.3-16.9173.500000114.6L76 I315 V316 A317 V321 E322L76-G319 WeakPolarHBondContact CD1-O 3.46Å; I315-G319 PolarHBondContact O-N 2.92Å; V316-G319 PolarHBondContact O-N 2.78Å; A317-G319 PolarHBondContact O-N 3.21Å; G319-V321 PolarHBondContact O-N 3.37Å; G319-E322 PolarHBondContact O-N 3.25Å
320T97.4Very high95.2Very high0 Ų017 Ų170%011%0.109CC..G310 helixtrans-65.8-14.4173.767.20000113.7K73 L76 A317 D318 E322 S323K73-T320 HydrophobicContact CB-CG2 3.68Å; L76-T320 HydrophobicContact CD2-CG2 4.28Å; L76-T320 HydrophobicContact CG-CG2 4.17Å; A317-T320 VanDerWaalsContact O-CB 3.24Å; A317-T320 WeakPolarHBondContact O-CB 3.45Å; A317-T320 WeakPolarHBondContact O-CG2 3.47Å; A317-T320 PolarHBondContact O-N 3.44Å; A317-T320 PolarHBondContact O-OG1 2.86Å; D318-T320 PolarHBondContact O-N 2.72Å; T320-E322 PolarHBondContact O-N 3.37Å; T320-E322 VanDerWaalsContact O-N 3.09Å; T320-S323 WeakPolarHBondContact O-CB 3.44Å; T320-S323 PolarHBondContact O-N 3.04Å; T320-S323 PolarHBondContact O-OG 2.77Å
321V96.1Very high95.1Very high13 Ų1319.7 Ų19.78%0.07913%0.126CC..G310 helixtrans-52.6-27.7170.470.60000112.5D318 G319 S323 A324 L349 A487 L490 C505D318-V321 WeakPolarHBondContact O-CB 3.39Å; D318-V321 VanDerWaalsContact O-CG1 3.22Å; D318-V321 WeakPolarHBondContact O-CG1 3.46Å; D318-V321 PolarHBondContact O-N 3.12Å; G319-V321 PolarHBondContact O-N 3.37Å; V321-S323 PolarHBondContact O-N 3.39Å; V321-S323 VanDerWaalsContact O-N 3.15Å; V321-A324 WeakPolarHBondContact O-CB 3.36Å; V321-A324 PolarHBondContact O-N 2.97Å; V321-L349 HydrophobicContact CG1-CD2 4.24Å; V321-A487 HydrophobicContact CG2-CB 4.31Å; V321-L490 HydrophobicContact CG2-CB 4.31Å; V321-L490 HydrophobicContact CG2-CD2 3.72Å; V321-C505 HydrophobicContact CG2-CB 4.35Å; V321-C505 VanDerWaalsContact CG2-SG 3.52Å
322E94.3Very high95Very high12 Ų1224 Ų246%0.05614%0.144CC..G310 helixtrans-58.5-28.4175.7-174.9-87165.100112.9L76 G319 T320 A324 F325 I330 K357L76-E322 HydrophobicContact CD1-CB 4.07Å; G319-E322 PolarHBondContact O-N 3.25Å; T320-E322 PolarHBondContact O-N 3.37Å; T320-E322 VanDerWaalsContact O-N 3.09Å; E322-A324 PolarHBondContact O-N 3.31Å; E322-F325 WeakPolarHBondContact O-CD2 3.48Å; E322-F325 PolarHBondContact O-N 2.86Å; E322-I330 HydrophobicContact CG-CB 4.21Å; E322-I330 HydrophobicContact CG-CD1 3.9Å; E322-I330 HydrophobicContact CG-CG1 4.08Å; E322-I330 PolarHBondContact OE1-N 2.99Å; E322-K357 VanDerWaalsContact OE1-CE 3.27Å; E322-K357 WeakPolarHBondContact OE1-CE 3.2Å; E322-K357 IonicContact OE1-NZ 2.69Å; E322-K357 PolarHBondContact OE1-NZ 3.28Å; E322-K357 WeakPolarHBondContact OE2-CE 3.27Å; E322-K357 IonicContact OE2-NZ 3.57Å; E322-K357 PolarHBondContact OE2-NZ 3.15Å
323S93.3Very high94.8Very high25 Ų2529.2 Ų29.218%0.17517%0.172CC..G310 helixtrans-65.6-9.3176.164.60000113.9K73 T320 V321 F325K73-S323 PolarHBondContact NZ-OG 3.32Å; T320-S323 WeakPolarHBondContact O-CB 3.44Å; T320-S323 PolarHBondContact O-N 3.04Å; T320-S323 PolarHBondContact O-OG 2.77Å; V321-S323 PolarHBondContact O-N 3.39Å; V321-S323 VanDerWaalsContact O-N 3.15Å; S323-F325 PolarHBondContact O-N 2.99Å
324A92.2Very high94.8Very high7 Ų728.8 Ų28.86%0.05817%0.165CC..G310 helixtrans-70.2-18.3170.200000113.6Y44 L66 V321 E322 C326 L490Y44-A324 HydrophobicContact CE1-CB 3.84Å; L66-A324 HydrophobicContact CD1-CB 4.43Å; V321-A324 WeakPolarHBondContact O-CB 3.36Å; V321-A324 PolarHBondContact O-N 2.97Å; E322-A324 PolarHBondContact O-N 3.31Å; A324-C326 PolarHBondContact O-N 3.45Å; A324-L490 HydrophobicContact CB-CD2 4.39Å
325F92.1Very high94.8Very high10 Ų1029.4 Ų29.44%0.04417%0.169CC..  trans-96.879-178.5-52.1-66.1000111.6E322 S323 H328 P329 L451 I453 L490 E493E322-F325 WeakPolarHBondContact O-CD2 3.48Å; E322-F325 PolarHBondContact O-N 2.86Å; S323-F325 PolarHBondContact O-N 2.99Å; F325-H328 WeakPolarHBondContact CB-O 3.02Å; F325-P329 VanDerWaalsContact O-CA 3.23Å; F325-P329 WeakPolarHBondContact O-CA 3.43Å; F325-L451 HydrophobicContact CD1-CD1 4.06Å; F325-L451 HydrophobicContact CD1-CD2 4.06Å; F325-L451 HydrophobicContact CD2-CD2 4.27Å; F325-L451 HydrophobicContact CE1-CD1 3.66Å; F325-L451 HydrophobicContact CE1-CD2 3.92Å; F325-L451 HydrophobicContact CE1-CG 4.43Å; F325-L451 HydrophobicContact CE2-CD2 4.14Å; F325-L451 HydrophobicContact CG-CD2 4.24Å; F325-L451 HydrophobicContact CZ-CD1 4.28Å; F325-L451 HydrophobicContact CZ-CD2 3.95Å; F325-I453 HydrophobicContact CE2-CD1 4.2Å; F325-I453 HydrophobicContact CZ-CD1 3.65Å; F325-I453 HydrophobicContact CZ-CG1 4.29Å; F325-L490 HydrophobicContact CE1-CD2 4.07Å; F325-L490 HydrophobicContact CE2-CD2 4.35Å; F325-L490 HydrophobicContact CZ-CD2 3.6Å; F325-E493 VanDerWaalsContact C-OE2 3.26Å; F325-E493 WeakPolarHBondContact CA-OE2 3.05Å; F325-E493 HydrophobicContact CD1-CG 3.97Å
326C87.1Confident94.7Very high70 Ų7029.4 Ų29.447%0.47317%0.169SC..SBendtrans-76.9-41.4179.8-177.60000113A324 E493A324-C326 PolarHBondContact O-N 3.45Å; C326-E493 PolarHBondContact N-OE2 2.94Å
327A86.3Confident94.6Very high40 Ų4029.3 Ų29.333%0.33117%0.168SC..SBendtrans-83.1-30.4-179.100000112.6I41 T42 P329 E493I41-A327 HydrophobicContact CG2-CB 3.75Å; T42-A327 WeakPolarHBondContact O-CB 3.43Å; A327-P329 WeakPolarHBondContact O-CD 3.45Å; A327-E493 PolarHBondContact N-OE2 2.83Å
328H91Very high94.3Very high56 Ų5629.2 Ų29.226%0.25917%0.168SC..SBendtrans-124.360.7178.1-53.378.6000110.9F325 V474 E493F325-H328 WeakPolarHBondContact CB-O 3.02Å; H328-V474 WeakPolarHBondContact CE1-CG2 3.48Å; H328-V474 VanDerWaalsContact ND1-CG2 3.32Å; H328-V474 WeakPolarHBondContact ND1-CG2 3.45Å; H328-E493 WeakPolarHBondContact CB-OE1 3.5Å; H328-E493 IonicContact CE1-OE1 2.79Å; H328-E493 IonicContact CG-OE1 3.05Å; H328-E493 PolarHBondContact N-OE1 3.09Å; H328-E493 IonicContact ND1-OE1 3.97Å; H328-E493 PolarHBondContact ND1-OE1 3.37Å
329P91.7Very high93.9Very high61 Ų6130 Ų3040%0.39617%0.17SC..  trans-61.8144-179.928.3-35.4000110.3F325 A327 T331F325-P329 VanDerWaalsContact O-CA 3.23Å; F325-P329 WeakPolarHBondContact O-CA 3.43Å; A327-P329 WeakPolarHBondContact O-CD 3.45Å; P329-T331 WeakPolarHBondContact O-CG2 3.45Å; P329-T331 PolarHBondContact O-N 2.95Å
330I94.1Very high93.4Very high8 Ų830.6 Ų30.64%0.04117%0.174CC..  trans-74.4130.2176.6-57.9179.4000108.5E322 D334 L354 K357 S359 L382E322-I330 HydrophobicContact CG-CB 4.21Å; E322-I330 HydrophobicContact CG-CD1 3.9Å; E322-I330 HydrophobicContact CG-CG1 4.08Å; E322-I330 PolarHBondContact OE1-N 2.99Å; I330-D334 HydrophobicContact CG2-CB 4.39Å; I330-L354 HydrophobicContact CD1-CD1 4.33Å; I330-L354 HydrophobicContact CG2-CG 4.32Å; I330-K357 HydrophobicContact CB-CG 4.26Å; I330-K357 HydrophobicContact CG2-CB 4.19Å; I330-K357 HydrophobicContact CG2-CG 4.02Å; I330-K357 WeakPolarHBondContact O-CD 3.09Å; I330-S359 WeakPolarHBondContact CG2-OG 3.34Å; I330-L382 HydrophobicContact CD1-CD2 3.72Å; I330-L382 HydrophobicContact CG1-CD2 4.02Å
331T95.5Very high92.7Very high58 Ų5833.3 Ų33.336%0.35619%0.191SC..  trans-124.8167.7-177.271.60000111.6P329 D333 D334 S359P329-T331 WeakPolarHBondContact O-CG2 3.45Å; P329-T331 PolarHBondContact O-N 2.95Å; T331-D333 PolarHBondContact O-N 2.89Å; T331-D333 VanDerWaalsContact O-N 3.09Å; T331-D333 PolarHBondContact OG1-N 3.5Å; T331-D334 PolarHBondContact N-OD2 2.9Å; T331-D334 WeakPolarHBondContact O-CB 3.31Å; T331-D334 PolarHBondContact O-N 3.47Å; T331-D334 VanDerWaalsContact O-N 3.11Å; T331-D334 PolarHBondContact OG1-OD2 3.42Å; T331-S359 WeakPolarHBondContact O-CB 3.33Å; T331-S359 PolarHBondContact O-OG 3.12Å
332K95.9Very high92.3Very high101 Ų10132.7 Ų32.744%0.43919%0.188SC..THydrogen-bonded Turntrans-60.7-16.8174.267.1177.7-176.6177.60114.7T94 K357 G358T94-K332 HydrophobicContact CG2-CB 4.17Å; K332-K357 WeakPolarHBondContact CB-O 3.43Å; K332-G358 WeakPolarHBondContact CA-O 3.46Å
333D95.8Very high91.8Very high110 Ų11032.5 Ų32.559%0.58819%0.188SC*.THydrogen-bonded Turntrans-88.1-10.4-179.4-64.2-48.8000112.4T331T331-D333 PolarHBondContact O-N 2.89Å; T331-D333 VanDerWaalsContact O-N 3.09Å; T331-D333 PolarHBondContact OG1-N 3.5Å
334D97.8Very high91.4Very high16 Ų1633.8 Ų33.89%0.08619%0.191CC..  trans-72.3149178.8-76.4-65.9000113.3I330 T331 K360 T381 L382I330-D334 HydrophobicContact CG2-CB 4.39Å; T331-D334 PolarHBondContact N-OD2 2.9Å; T331-D334 WeakPolarHBondContact O-CB 3.31Å; T331-D334 PolarHBondContact O-N 3.47Å; T331-D334 VanDerWaalsContact O-N 3.11Å; T331-D334 PolarHBondContact OG1-OD2 3.42Å; D334-K360 PolarHBondContact O-N 3.3Å; D334-T381 WeakPolarHBondContact CA-OG1 3.5Å; D334-T381 WeakPolarHBondContact CB-OG1 3.39Å; D334-T381 VanDerWaalsContact OD1-CB 3.32Å; D334-T381 WeakPolarHBondContact OD1-CB 3.29Å; D334-T381 PolarHBondContact OD1-OG1 3.17Å; D334-L382 HydrophobicContact CB-CD1 3.71Å; D334-L382 WeakPolarHBondContact OD1-CD1 3.41Å
335I97.9Very high91.4Very high27 Ų2733.7 Ų33.714%0.13819%0.19CC..EExtended strand (participates in β ladder)trans-131.2119.6-178.3-52.6178.1000108.7W115 K360 L378 P380 T381 L382W115-I335 HydrophobicContact CH2-CG2 4.04Å; I335-K360 CarbonylContact C-O 3.55Å; I335-K360 VanDerWaalsContact CA-O 3.3Å; I335-K360 WeakPolarHBondContact CA-O 3.46Å; I335-K360 HydrophobicContact CD1-CD 4.48Å; I335-K360 HydrophobicContact CG1-CB 4.14Å; I335-K360 HydrophobicContact CG1-CD 4.14Å; I335-K360 HydrophobicContact CG2-CB 4.49Å; I335-L378 HydrophobicContact CG2-CD1 3.65Å; I335-L378 HydrophobicContact CG2-CD2 4.08Å; I335-L378 HydrophobicContact CG2-CG 3.75Å; I335-P380 CarbonylContact O-C 3.47Å; I335-P380 WeakPolarHBondContact O-CA 3.41Å; I335-P380 WeakPolarHBondContact O-CB 3.31Å; I335-T381 PolarHBondContact N-OG1 3.22Å; I335-T381 PolarHBondContact O-N 3.36Å; I335-T381 PolarHBondContact O-OG1 2.73Å; I335-L382 PolarHBondContact O-N 2.92Å
336M97.5Very high91.4Very high0 Ų034.9 Ų34.90%020%0.195CC..EExtended strand (participates in β ladder)trans-99.9140.2172.4-175.4176.281.400111.2M350 E351 L354 K360 I361 G362 L382 P384M336-M350 HydrophobicContact CE-CB 4.05Å; M336-M350 HydrophobicContact SD-CB 3.69Å; M336-M350 HydrophobicContact SD-CE 3.86Å; M336-M350 HydrophobicContact SD-CG 4.46Å; M336-E351 HydrophobicContact CE-CG 3.51Å; M336-L354 HydrophobicContact CB-CD2 3.35Å; M336-L354 HydrophobicContact CG-CD2 4.43Å; M336-L354 HydrophobicContact SD-CD1 4.12Å; M336-L354 HydrophobicContact SD-CD2 4.35Å; M336-K360 PolarHBondContact N-O 2.97Å; M336-I361 HydrophobicContact CE-CG1 4.49Å; M336-I361 HydrophobicContact CE-CG2 4.26Å; M336-G362 PolarHBondContact O-N 2.98Å; M336-L382 WeakPolarHBondContact CA-O 3.46Å; M336-L382 HydrophobicContact CB-CB 4.02Å; M336-L382 HydrophobicContact CG-CB 4.15Å; M336-P384 HydrophobicContact CG-CG 4.17Å; M336-P384 HydrophobicContact SD-CG 3.88Å
337I95.7Very high91.6Very high0 Ų031.6 Ų31.60%017%0.172CC..EExtended strand (participates in β ladder)trans-82.1121.5163.5-177.570.1000109.2Y339 G362 L371 D374 M375 L378 P380 L382 F383I337-Y339 HydrophobicContact CG1-CD1 4.49Å; I337-G362 CarbonylContact C-O 3.53Å; I337-G362 WeakPolarHBondContact CA-O 3.46Å; I337-L371 HydrophobicContact CD1-CD1 4.38Å; I337-L371 HydrophobicContact CG1-CD1 3.94Å; I337-D374 HydrophobicContact CD1-CB 4.4Å; I337-M375 HydrophobicContact CB-CG 4.42Å; I337-M375 HydrophobicContact CG1-CG 4.1Å; I337-M375 HydrophobicContact CG2-CE 4.13Å; I337-M375 HydrophobicContact CG2-CG 4.33Å; I337-M375 HydrophobicContact CG2-SD 4.39Å; I337-L378 HydrophobicContact CB-CD2 3.89Å; I337-L378 HydrophobicContact CD1-CD2 3.62Å; I337-L378 HydrophobicContact CG1-CD2 4.35Å; I337-P380 HydrophobicContact CB-CB 4.13Å; I337-P380 HydrophobicContact CB-CG 4.17Å; I337-P380 HydrophobicContact CG2-CB 4.25Å; I337-P380 HydrophobicContact CG2-CG 4.14Å; I337-L382 PolarHBondContact N-O 2.74Å; I337-F383 HydrophobicContact CG2-CB 4.34Å; I337-F383 HydrophobicContact CG2-CD2 3.43Å; I337-F383 VanDerWaalsContact CG2-CD2 3.43Å; I337-F383 HydrophobicContact CG2-CE2 4.07Å; I337-F383 HydrophobicContact CG2-CG 4.23Å
338S93.4Very high92Very high0 Ų029.7 Ų29.70%016%0.157CC..EExtended strand (participates in β ladder)trans-102.5119.6176.3176.80000110.5N151 E347 E351 G362 Y363 Y364N151-S338 PolarHBondContact ND2-OG 3.38Å; S338-E347 WeakPolarHBondContact CA-OE1 3.34Å; S338-E347 PolarHBondContact OG-OE1 3.27Å; S338-E347 VanDerWaalsContact OG-OE1 3.09Å; S338-E351 WeakPolarHBondContact CB-OE1 3.45Å; S338-E351 PolarHBondContact OG-OE1 3.5Å; S338-G362 PolarHBondContact N-O 2.94Å; S338-Y363 WeakPolarHBondContact O-CA 3.12Å; S338-Y363 VanDerWaalsContact OG-CD1 3.3Å; S338-Y363 WeakPolarHBondContact OG-CD1 3.39Å; S338-Y363 WeakPolarHBondContact OG-CE1 3.49Å; S338-Y364 WeakPolarHBondContact O-CD1 3.32Å; S338-Y364 PolarHBondContact O-N 3.01Å
339Y89.3Confident92.2Very high15 Ų1527.4 Ų27.46%0.05915%0.146CC..  trans-154-15.1-178.878.3-74.8000113.3I337 E347 L371 F383 P384 V385 L389I337-Y339 HydrophobicContact CG1-CD1 4.49Å; Y339-E347 PolarHBondContact N-OE1 3.13Å; Y339-L371 HydrophobicContact CD1-CD1 4.3Å; Y339-L371 HydrophobicContact CD1-CD2 4.47Å; Y339-L371 HydrophobicContact CD2-CD2 4.03Å; Y339-L371 HydrophobicContact CE1-CD2 4.48Å; Y339-L371 HydrophobicContact CE2-CD2 4.02Å; Y339-L371 HydrophobicContact CG-CD1 4.07Å; Y339-L371 HydrophobicContact CG-CD2 4.26Å; Y339-F383 HydrophobicContact CD1-CE2 4.32Å; Y339-F383 AromaticContact CE1-CD2 3.99Å; Y339-F383 HydrophobicContact CE1-CD2 3.99Å; Y339-F383 AromaticContact CE1-CE2 3.45Å; Y339-F383 HydrophobicContact CE1-CE2 3.45Å; Y339-F383 VanDerWaalsContact CE1-CE2 3.45Å; Y339-F383 AromaticContact CZ-CE2 3.85Å; Y339-P384 WeakPolarHBondContact CE1-O 3.23Å; Y339-P384 PolarHBondContact OH-O 3.42Å; Y339-V385 WeakPolarHBondContact OH-CA 3.26Å; Y339-L389 HydrophobicContact CE2-CD2 3.84Å; Y339-L389 WeakPolarHBondContact OH-CD2 3.39Å
340L87Confident92.4Very high14 Ų1425.3 Ų25.37%0.07313%0.131CC..SBendtrans-75.8146.6172.7-60.5179.1000108.7N151 L342 F346 E347 P384 V386N151-L340 PolarHBondContact ND2-O 3.19Å; N151-L340 PolarHBondContact OD1-O 3.08Å; L340-L342 PolarHBondContact O-N 3.38Å; L340-F346 HydrophobicContact CD1-CD1 3.72Å; L340-F346 HydrophobicContact CD1-CE1 3.7Å; L340-E347 HydrophobicContact CB-CB 4.04Å; L340-E347 HydrophobicContact CB-CG 4.21Å; L340-E347 PolarHBondContact N-OE1 3.35Å; L340-E347 VanDerWaalsContact N-OE1 3.13Å; L340-E347 WeakPolarHBondContact O-CG 3.48Å; L340-P384 HydrophobicContact CD1-CB 3.97Å; L340-P384 HydrophobicContact CD1-CG 4.46Å; L340-V386 HydrophobicContact CD1-CG1 4.42Å; L340-V386 HydrophobicContact CD2-CG1 3.85Å; L340-V386 HydrophobicContact CD2-CG2 4.38Å
341P83Confident92.5Very high56 Ų5625 Ų2536%0.36413%0.13SC..  trans-61126.4-176.5-21.331.7000112.7A343 H344P341-A343 PolarHBondContact O-N 3.29Å; P341-H344 WeakPolarHBondContact O-CB 3.39Å; P341-H344 PolarHBondContact O-N 2.91Å
342L88Confident92.5Very high1 Ų122.3 Ų22.31%0.00511%0.113CC..THydrogen-bonded Turntrans-67.5-12.1174.4-82.1162.5000112.5N151 W165 V166 L340 H344 E347 R348 E351 Y363N151-L342 WeakPolarHBondContact ND2-CG 3.48Å; N151-L342 WeakPolarHBondContact OD1-CB 3.44Å; N151-L342 WeakPolarHBondContact OD1-CD1 3.4Å; N151-L342 WeakPolarHBondContact OD1-CG 3.48Å; N151-L342 PolarHBondContact OD1-N 3.44Å; W165-L342 HydrophobicContact CB-CD1 3.89Å; W165-L342 HydrophobicContact CD2-CB 3.55Å; W165-L342 HydrophobicContact CD2-CD1 3.76Å; W165-L342 HydrophobicContact CD2-CG 4.22Å; W165-L342 HydrophobicContact CE3-CB 3.69Å; W165-L342 HydrophobicContact CE3-CD1 3.58Å; W165-L342 HydrophobicContact CE3-CD2 4.3Å; W165-L342 HydrophobicContact CE3-CG 4.04Å; W165-L342 HydrophobicContact CG-CB 4.12Å; W165-L342 HydrophobicContact CG-CD1 3.91Å; W165-L342 HydrophobicContact CH2-CB 3.88Å; W165-L342 WeakPolarHBondContact CH2-O 3.49Å; W165-L342 HydrophobicContact CZ2-CB 3.73Å; W165-L342 WeakPolarHBondContact CZ2-O 3.31Å; W165-L342 HydrophobicContact CZ3-CB 3.84Å; W165-L342 HydrophobicContact CZ3-CD1 4.3Å; W165-L342 HydrophobicContact CZ3-CD2 4.19Å; W165-L342 HydrophobicContact CZ3-CG 4.32Å; V166-L342 HydrophobicContact CG2-CD1 4.33Å; L340-L342 PolarHBondContact O-N 3.38Å; L342-H344 PolarHBondContact O-N 3.1Å; L342-E347 HydrophobicContact CD2-CB 4.28Å; L342-E347 HydrophobicContact CD2-CG 3.92Å; L342-E347 HydrophobicContact CG-CG 4.22Å; L342-R348 HydrophobicContact CD2-CG 3.84Å; L342-R348 WeakPolarHBondContact O-CD 3.33Å; L342-R348 WeakPolarHBondContact O-CG 3.33Å; L342-E351 VanDerWaalsContact CD2-CD 3.49Å; L342-E351 HydrophobicContact CD2-CG 4.22Å; L342-E351 WeakPolarHBondContact CD2-OE2 3.16Å; L342-Y363 HydrophobicContact CD1-CE1 4.03Å
343A83.5Confident92.5Very high8 Ų817.8 Ų17.87%0.0669%0.094CC..THydrogen-bonded Turntrans-68.7-12.6166.900000113.3P181 Y183 P341P181-A343 HydrophobicContact CB-CB 3.93Å; Y183-A343 HydrophobicContact CD1-CB 3.88Å; Y183-A343 HydrophobicContact CG-CB 4.28Å; P341-A343 PolarHBondContact O-N 3.29Å
344H84.4Confident92.5Very high52 Ų5212.6 Ų12.624%0.2417%0.066CC..SBendtrans-102.1136.2173.4-60-43.6000110.4P341 L342 F346 E347 R348P341-H344 WeakPolarHBondContact O-CB 3.39Å; P341-H344 PolarHBondContact O-N 2.91Å; L342-H344 PolarHBondContact O-N 3.1Å; H344-F346 PolarHBondContact O-N 3.2Å; H344-F346 VanDerWaalsContact O-N 3.16Å; H344-E347 PolarHBondContact O-N 2.84Å; H344-R348 PolarHBondContact O-N 3.28Å
345M92.8Very high92.4Very high5 Ų511.9 Ų11.93%0.0256%0.063CC..Hα-helixtrans-65.9-19.4-174.9-70-52.8-61.700114.4T294 C296 L310 I315 R348 L349 T482 V485 A486T294-M345 HydrophobicContact CG2-SD 4.29Å; C296-M345 PolarHBondContact SG-SD 2.96Å; L310-M345 HydrophobicContact CD1-CE 3.81Å; L310-M345 HydrophobicContact CD1-CG 3.81Å; L310-M345 HydrophobicContact CD1-SD 3.75Å; I315-M345 HydrophobicContact CD1-CE 3.86Å; I315-M345 HydrophobicContact CG1-CE 3.89Å; M345-R348 HydrophobicContact CE-CB 4.3Å; M345-R348 PolarHBondContact O-N 3.07Å; M345-R348 HydrophobicContact SD-CB 4.43Å; M345-L349 VanDerWaalsContact O-CB 3.27Å; M345-L349 WeakPolarHBondContact O-CB 3.49Å; M345-L349 PolarHBondContact O-N 2.87Å; M345-T482 HydrophobicContact CG-CG2 4.1Å; M345-V485 WeakPolarHBondContact CB-O 3.44Å; M345-V485 HydrophobicContact CE-CG1 3.68Å; M345-V485 VanDerWaalsContact CG-O 3.31Å; M345-V485 WeakPolarHBondContact CG-O 3.3Å; M345-A486 HydrophobicContact CB-CB 4.07Å
346F92Very high92.3Very high34 Ų3410.7 Ų10.715%0.1496%0.056CC..Hα-helixtrans-60.6-51176178.5-147.8000111.6L340 H344 M350 P384 I453L340-F346 HydrophobicContact CD1-CD1 3.72Å; L340-F346 HydrophobicContact CD1-CE1 3.7Å; H344-F346 PolarHBondContact O-N 3.2Å; H344-F346 VanDerWaalsContact O-N 3.16Å; F346-M350 HydrophobicContact CD2-CG 4.28Å; F346-M350 HydrophobicContact CE2-CG 4.04Å; F346-M350 HydrophobicContact CE2-SD 4.44Å; F346-M350 WeakPolarHBondContact O-CG 3.46Å; F346-M350 PolarHBondContact O-N 3.42Å; F346-P384 HydrophobicContact CE1-CB 4.21Å; F346-P384 HydrophobicContact CZ-CB 3.92Å; F346-I453 HydrophobicContact CE2-CG2 3.91Å; F346-I453 HydrophobicContact CZ-CB 4.37Å; F346-I453 HydrophobicContact CZ-CG2 3.92Å
347E92.1Very high92.2Very high1 Ų112 Ų121%0.0056%0.062CC..Hα-helixtrans-66.9-40.2177.2-166.880.3143.100111.1S338 Y339 L340 L342 H344 L349 M350 E351 P384S338-E347 WeakPolarHBondContact CA-OE1 3.34Å; S338-E347 PolarHBondContact OG-OE1 3.27Å; S338-E347 VanDerWaalsContact OG-OE1 3.09Å; Y339-E347 PolarHBondContact N-OE1 3.13Å; L340-E347 HydrophobicContact CB-CB 4.04Å; L340-E347 HydrophobicContact CB-CG 4.21Å; L340-E347 PolarHBondContact N-OE1 3.35Å; L340-E347 VanDerWaalsContact N-OE1 3.13Å; L340-E347 WeakPolarHBondContact O-CG 3.48Å; L342-E347 HydrophobicContact CD2-CB 4.28Å; L342-E347 HydrophobicContact CD2-CG 3.92Å; L342-E347 HydrophobicContact CG-CG 4.22Å; H344-E347 PolarHBondContact O-N 2.84Å; E347-L349 PolarHBondContact O-N 2.76Å; E347-M350 WeakPolarHBondContact O-CB 3.28Å; E347-M350 PolarHBondContact O-N 2.91Å; E347-E351 PolarHBondContact O-N 2.98Å; E347-P384 VanDerWaalsContact OE2-CG 3.28Å; E347-P384 WeakPolarHBondContact OE2-CG 3.4Å
348R93.6Very high92.3Very high1 Ų112 Ų120%0.0046%0.063CC..Hα-helixtrans-62-44.9178.8-69.8178.877.6169.28.1112.4W165 E169 Y173 N179 T294 L342 H344 M345 M350 E351 I352W165-R348 HydrophobicContact CH2-CG 4.13Å; W165-R348 HydrophobicContact CZ3-CG 4.41Å; E169-R348 IonicContact OE1-CZ 3.95Å; E169-R348 VanDerWaalsContact OE1-CZ 3.24Å; E169-R348 IonicContact OE1-NE 3.34Å; E169-R348 PolarHBondContact OE1-NE 2.88Å; E169-R348 IonicContact OE1-NH2 3.43Å; E169-R348 PolarHBondContact OE1-NH2 3.08Å; Y173-R348 PolarHBondContact OH-NH2 3.36Å; Y173-R348 VanDerWaalsContact OH-NH2 3.15Å; N179-R348 PolarHBondContact OD1-NH2 3.18Å; T294-R348 PolarHBondContact OG1-NH1 3.28Å; L342-R348 HydrophobicContact CD2-CG 3.84Å; L342-R348 WeakPolarHBondContact O-CD 3.33Å; L342-R348 WeakPolarHBondContact O-CG 3.33Å; H344-R348 PolarHBondContact O-N 3.28Å; M345-R348 HydrophobicContact CE-CB 4.3Å; M345-R348 PolarHBondContact O-N 3.07Å; M345-R348 HydrophobicContact SD-CB 4.43Å; R348-M350 VanDerWaalsContact C-N 3.27Å; R348-M350 PolarHBondContact O-N 3.12Å; R348-E351 PolarHBondContact O-N 2.83Å; R348-I352 HydrophobicContact CB-CD1 4.49Å; R348-I352 WeakPolarHBondContact O-CB 3.39Å; R348-I352 WeakPolarHBondContact O-CD1 3.42Å; R348-I352 WeakPolarHBondContact O-CG1 3.46Å; R348-I352 PolarHBondContact O-N 3.18Å
349L96.3Very high92.5Very high8 Ų812 Ų124%0.0426%0.063CC..Hα-helixtrans-59.5-43.8177.6-179.564.3000110.5D318 V321 M345 E347 I352 C353 V485 A486 A487D318-L349 HydrophobicContact CB-CD1 3.95Å; D318-L349 HydrophobicContact CB-CD2 4.44Å; D318-L349 WeakPolarHBondContact OD2-CD2 3.34Å; V321-L349 HydrophobicContact CG1-CD2 4.24Å; M345-L349 VanDerWaalsContact O-CB 3.27Å; M345-L349 WeakPolarHBondContact O-CB 3.49Å; M345-L349 PolarHBondContact O-N 2.87Å; E347-L349 PolarHBondContact O-N 2.76Å; L349-I352 PolarHBondContact O-N 3.09Å; L349-C353 WeakPolarHBondContact O-CB 3.03Å; L349-C353 PolarHBondContact O-N 3.2Å; L349-C353 PolarHBondContact O-SG 3.37Å; L349-V485 HydrophobicContact CD1-CG1 4.3Å; L349-A486 HydrophobicContact CB-CB 4.21Å; L349-A486 HydrophobicContact CD2-CB 3.91Å; L349-A487 HydrophobicContact CD2-CB 3.9Å
350M95.8Very high92.8Very high16 Ų1613.8 Ų13.88%0.0797%0.071CC..Hα-helixtrans-59.1-51.9175.7-70.7-62.2-59.900111.6M336 F346 E347 R348 I352 C353 L354 L382 P384 I453M336-M350 HydrophobicContact CE-CB 4.05Å; M336-M350 HydrophobicContact SD-CB 3.69Å; M336-M350 HydrophobicContact SD-CE 3.86Å; M336-M350 HydrophobicContact SD-CG 4.46Å; F346-M350 HydrophobicContact CD2-CG 4.28Å; F346-M350 HydrophobicContact CE2-CG 4.04Å; F346-M350 HydrophobicContact CE2-SD 4.44Å; F346-M350 WeakPolarHBondContact O-CG 3.46Å; F346-M350 PolarHBondContact O-N 3.42Å; E347-M350 WeakPolarHBondContact O-CB 3.28Å; E347-M350 PolarHBondContact O-N 2.91Å; R348-M350 VanDerWaalsContact C-N 3.27Å; R348-M350 PolarHBondContact O-N 3.12Å; M350-I352 VanDerWaalsContact C-N 3.32Å; M350-I352 PolarHBondContact O-N 3.29Å; M350-C353 WeakPolarHBondContact O-CB 3.45Å; M350-C353 PolarHBondContact O-N 2.98Å; M350-L354 HydrophobicContact CE-CD1 4.41Å; M350-L354 WeakPolarHBondContact O-CD1 3.31Å; M350-L354 PolarHBondContact O-N 2.84Å; M350-L382 HydrophobicContact CE-CD2 4.15Å; M350-P384 HydrophobicContact CG-CB 4.29Å; M350-I453 HydrophobicContact CE-CD1 3.78Å; M350-I453 HydrophobicContact SD-CD1 3.67Å
351E95.3Very high93.3Very high2 Ų213.1 Ų13.11%0.0097%0.067CC..Hα-helixtrans-59.8-41179.4-73.4-163.1-17500112.2V166 M336 S338 L342 E347 R348 L354 M355 I361 Y363V166-E351 WeakPolarHBondContact CG2-OE2 3.26Å; M336-E351 HydrophobicContact CE-CG 3.51Å; S338-E351 WeakPolarHBondContact CB-OE1 3.45Å; S338-E351 PolarHBondContact OG-OE1 3.5Å; L342-E351 VanDerWaalsContact CD2-CD 3.49Å; L342-E351 HydrophobicContact CD2-CG 4.22Å; L342-E351 WeakPolarHBondContact CD2-OE2 3.16Å; E347-E351 PolarHBondContact O-N 2.98Å; R348-E351 PolarHBondContact O-N 2.83Å; E351-L354 PolarHBondContact O-N 2.97Å; E351-M355 HydrophobicContact CB-CE 4.16Å; E351-M355 VanDerWaalsContact O-CG 3.29Å; E351-M355 WeakPolarHBondContact O-CG 3.43Å; E351-M355 PolarHBondContact O-N 2.83Å; E351-I361 HydrophobicContact CB-CD1 3.8Å; E351-I361 HydrophobicContact CG-CD1 3.75Å; E351-I361 HydrophobicContact CG-CG1 4.34Å; E351-I361 HydrophobicContact CG-CG2 4.17Å; E351-Y363 WeakPolarHBondContact OE1-CE1 3.49Å; E351-Y363 PolarHBondContact OE1-OH 3.2Å; E351-Y363 VanDerWaalsContact OE1-OH 3.09Å; E351-Y363 PolarHBondContact OE2-OH 2.96Å
352I94.6Very high93.8Very high2 Ų210.4 Ų10.41%0.015%0.05CC..Hα-helixtrans-66.3-43.5179.2-66.7166000111.1V83 A86 I315 R348 L349 M350 L354 M355 M356V83-I352 HydrophobicContact CG1-CD1 3.92Å; V83-I352 HydrophobicContact CG1-CG1 4.05Å; V83-I352 HydrophobicContact CG2-CD1 4.02Å; A86-I352 HydrophobicContact CB-CG2 4.26Å; I315-I352 HydrophobicContact CG2-CD1 3.4Å; I315-I352 HydrophobicContact CG2-CG2 4.37Å; R348-I352 HydrophobicContact CB-CD1 4.49Å; R348-I352 WeakPolarHBondContact O-CB 3.39Å; R348-I352 WeakPolarHBondContact O-CD1 3.42Å; R348-I352 WeakPolarHBondContact O-CG1 3.46Å; R348-I352 PolarHBondContact O-N 3.18Å; L349-I352 PolarHBondContact O-N 3.09Å; M350-I352 VanDerWaalsContact C-N 3.32Å; M350-I352 PolarHBondContact O-N 3.29Å; I352-L354 VanDerWaalsContact C-N 3.28Å; I352-L354 PolarHBondContact O-N 3.18Å; I352-M355 PolarHBondContact O-N 2.78Å; I352-M356 HydrophobicContact CG2-CE 4.17Å; I352-M356 WeakPolarHBondContact O-CG 3.45Å; I352-M356 PolarHBondContact O-N 2.91Å
353C96.2Very high94Very high6 Ų610.4 Ų10.44%0.0415%0.05CC..Hα-helixtrans-55.6-44172.6-750000111.9L349 M350 K357L349-C353 WeakPolarHBondContact O-CB 3.03Å; L349-C353 PolarHBondContact O-N 3.2Å; L349-C353 PolarHBondContact O-SG 3.37Å; M350-C353 WeakPolarHBondContact O-CB 3.45Å; M350-C353 PolarHBondContact O-N 2.98Å; C353-K357 WeakPolarHBondContact O-CG 3.36Å; C353-K357 PolarHBondContact O-N 3.04Å
354L96.7Very high94.3Very high0 Ų011 Ų110%05%0.05CC..Hα-helixtrans-68-43.6178-90.781.7000112.6I330 M336 M350 E351 I352 M356 K357 G358 S359 I361 L382I330-L354 HydrophobicContact CD1-CD1 4.33Å; I330-L354 HydrophobicContact CG2-CG 4.32Å; M336-L354 HydrophobicContact CB-CD2 3.35Å; M336-L354 HydrophobicContact CG-CD2 4.43Å; M336-L354 HydrophobicContact SD-CD1 4.12Å; M336-L354 HydrophobicContact SD-CD2 4.35Å; M350-L354 HydrophobicContact CE-CD1 4.41Å; M350-L354 WeakPolarHBondContact O-CD1 3.31Å; M350-L354 PolarHBondContact O-N 2.84Å; E351-L354 PolarHBondContact O-N 2.97Å; I352-L354 VanDerWaalsContact C-N 3.28Å; I352-L354 PolarHBondContact O-N 3.18Å; L354-M356 VanDerWaalsContact C-N 3.33Å; L354-M356 PolarHBondContact O-N 3.28Å; L354-K357 CarbonylContact O-C 3.57Å; L354-K357 PolarHBondContact O-N 3.38Å; L354-K357 VanDerWaalsContact O-N 3.07Å; L354-G358 PolarHBondContact O-N 3.31Å; L354-S359 PolarHBondContact O-N 2.93Å; L354-S359 PolarHBondContact O-OG 3.41Å; L354-I361 HydrophobicContact CB-CD1 4.45Å; L354-I361 HydrophobicContact CB-CG1 4.31Å; L354-I361 HydrophobicContact CD2-CG1 4.07Å; L354-L382 HydrophobicContact CD1-CD2 3.86Å
355M95.3Very high94.4Very high1 Ų19 Ų91%0.0054%0.042CC..Hα-helixtrans-60.5-42178.7-73.3177.9-161.100111.7A86 I87 G90 L100 V166 E351 I352 K357 G358 I361A86-M355 CarbonylContact O-C 3.55Å; I87-M355 HydrophobicContact CB-SD 4.27Å; I87-M355 HydrophobicContact CD1-SD 4.27Å; I87-M355 HydrophobicContact CG1-SD 4.31Å; G90-M355 WeakPolarHBondContact CA-O 3.44Å; G90-M355 PolarHBondContact N-O 3.34Å; L100-M355 HydrophobicContact CD2-CE 4.39Å; V166-M355 HydrophobicContact CB-CE 4.45Å; V166-M355 HydrophobicContact CG1-CE 3.56Å; V166-M355 HydrophobicContact CG2-CE 3.98Å; E351-M355 HydrophobicContact CB-CE 4.16Å; E351-M355 VanDerWaalsContact O-CG 3.29Å; E351-M355 WeakPolarHBondContact O-CG 3.43Å; E351-M355 PolarHBondContact O-N 2.83Å; I352-M355 PolarHBondContact O-N 2.78Å; M355-K357 PolarHBondContact O-N 3.34Å; M355-G358 PolarHBondContact O-N 2.73Å; M355-G358 VanDerWaalsContact O-N 3.1Å; M355-I361 HydrophobicContact CE-CD1 3.71Å; M355-I361 HydrophobicContact CG-CD1 4.14Å
356M95.4Very high93.8Very high2 Ų29.5 Ų9.51%0.015%0.048CC..Hα-helixtrans-60.7-27.2175.6-69.9-172.8-7100113.5Y77 V80 A86 R89 I352 L354Y77-M356 HydrophobicContact CE2-CB 4.46Å; V80-M356 HydrophobicContact CB-SD 4.47Å; V80-M356 HydrophobicContact CG1-CG 3.97Å; V80-M356 HydrophobicContact CG1-SD 3.63Å; A86-M356 HydrophobicContact CB-CG 3.37Å; A86-M356 HydrophobicContact CB-SD 4.37Å; R89-M356 VanDerWaalsContact CD-O 3.28Å; R89-M356 WeakPolarHBondContact CD-O 3.44Å; R89-M356 WeakPolarHBondContact CG-O 3.29Å; R89-M356 PolarHBondContact NE-O 2.97Å; I352-M356 HydrophobicContact CG2-CE 4.17Å; I352-M356 WeakPolarHBondContact O-CG 3.45Å; I352-M356 PolarHBondContact O-N 2.91Å; L354-M356 VanDerWaalsContact C-N 3.33Å; L354-M356 PolarHBondContact O-N 3.28Å
357K96Very high93.2Very high28 Ų289.6 Ų9.612%0.1225%0.05CC..Hα-helixtrans-92-10.9179-64.3-69.4-176.3155.40113.2Y77 E322 I330 K332 C353 L354 M355 S359Y77-K357 HydrophobicContact CE2-CD 4.45Å; Y77-K357 WeakPolarHBondContact OH-CD 3.23Å; Y77-K357 VanDerWaalsContact OH-CE 3.24Å; Y77-K357 WeakPolarHBondContact OH-CE 3.16Å; Y77-K357 PolarHBondContact OH-NZ 3.25Å; E322-K357 VanDerWaalsContact OE1-CE 3.27Å; E322-K357 WeakPolarHBondContact OE1-CE 3.2Å; E322-K357 IonicContact OE1-NZ 2.69Å; E322-K357 PolarHBondContact OE1-NZ 3.28Å; E322-K357 WeakPolarHBondContact OE2-CE 3.27Å; E322-K357 IonicContact OE2-NZ 3.57Å; E322-K357 PolarHBondContact OE2-NZ 3.15Å; I330-K357 HydrophobicContact CB-CG 4.26Å; I330-K357 HydrophobicContact CG2-CB 4.19Å; I330-K357 HydrophobicContact CG2-CG 4.02Å; I330-K357 WeakPolarHBondContact O-CD 3.09Å; K332-K357 WeakPolarHBondContact CB-O 3.43Å; C353-K357 WeakPolarHBondContact O-CG 3.36Å; C353-K357 PolarHBondContact O-N 3.04Å; L354-K357 CarbonylContact O-C 3.57Å; L354-K357 PolarHBondContact O-N 3.38Å; L354-K357 VanDerWaalsContact O-N 3.07Å; M355-K357 PolarHBondContact O-N 3.34Å; K357-S359 VanDerWaalsContact C-N 3.33Å
358G97Very high92.7Very high1 Ų112.6 Ų12.61%0.017%0.069CC..THydrogen-bonded Turntrans76.321.2-172.800000113.4T94 Y118 K332 L354 M355T94-G358 VanDerWaalsContact CG2-CA 3.48Å; T94-G358 WeakPolarHBondContact CG2-O 3.49Å; Y118-G358 VanDerWaalsContact OH-C 3.23Å; Y118-G358 VanDerWaalsContact OH-CA 3.27Å; Y118-G358 WeakPolarHBondContact OH-CA 2.83Å; K332-G358 WeakPolarHBondContact CA-O 3.46Å; L354-G358 PolarHBondContact O-N 3.31Å; M355-G358 PolarHBondContact O-N 2.73Å; M355-G358 VanDerWaalsContact O-N 3.1Å
359S97.8Very high92.1Very high0 Ų021.8 Ų21.80%010%0.104CC..  trans-73.6178.3178-48.30000111.3Y118 I330 T331 L354 K357Y118-S359 PolarHBondContact OH-N 3.33Å; Y118-S359 PolarHBondContact OH-O 2.93Å; I330-S359 WeakPolarHBondContact CG2-OG 3.34Å; T331-S359 WeakPolarHBondContact O-CB 3.33Å; T331-S359 PolarHBondContact O-OG 3.12Å; L354-S359 PolarHBondContact O-N 2.93Å; L354-S359 PolarHBondContact O-OG 3.41Å; K357-S359 VanDerWaalsContact C-N 3.33Å
360K97.1Very high91.6Very high51 Ų5126 Ų2622%0.22212%0.121CC..EExtended strand (participates in β ladder)trans-113.5138.4-175.2-55.7175.3-155.4171.40110.5P98 W115 D334 I335 M336P98-K360 HydrophobicContact CB-CD 4.29Å; P98-K360 HydrophobicContact CB-CG 4.43Å; P98-K360 HydrophobicContact CG-CD 3.62Å; P98-K360 HydrophobicContact CG-CG 4.01Å; W115-K360 HydrophobicContact CE3-CB 4.39Å; W115-K360 HydrophobicContact CH2-CB 3.77Å; W115-K360 HydrophobicContact CZ3-CB 3.56Å; W115-K360 HydrophobicContact CZ3-CG 4.38Å; D334-K360 PolarHBondContact O-N 3.3Å; I335-K360 CarbonylContact C-O 3.55Å; I335-K360 VanDerWaalsContact CA-O 3.3Å; I335-K360 WeakPolarHBondContact CA-O 3.46Å; I335-K360 HydrophobicContact CD1-CD 4.48Å; I335-K360 HydrophobicContact CG1-CB 4.14Å; I335-K360 HydrophobicContact CG1-CD 4.14Å; I335-K360 HydrophobicContact CG2-CB 4.49Å; M336-K360 PolarHBondContact N-O 2.97Å
361I95.8Very high91.3Very high0 Ų025.6 Ų25.60%012%0.12CC..EExtended strand (participates in β ladder)trans-117.8110.7178.5-59.6158.2000107.9C99 L100 G101 M336 E351 L354 M355 Y363C99-I361 PolarHBondContact O-N 3.07Å; L100-I361 CarbonylContact C-O 3.42Å; L100-I361 WeakPolarHBondContact CA-O 3.19Å; L100-I361 HydrophobicContact CD2-CB 4.04Å; L100-I361 HydrophobicContact CD2-CD1 4.03Å; G101-I361 PolarHBondContact N-O 2.77Å; M336-I361 HydrophobicContact CE-CG1 4.49Å; M336-I361 HydrophobicContact CE-CG2 4.26Å; E351-I361 HydrophobicContact CB-CD1 3.8Å; E351-I361 HydrophobicContact CG-CD1 3.75Å; E351-I361 HydrophobicContact CG-CG1 4.34Å; E351-I361 HydrophobicContact CG-CG2 4.17Å; L354-I361 HydrophobicContact CB-CD1 4.45Å; L354-I361 HydrophobicContact CB-CG1 4.31Å; L354-I361 HydrophobicContact CD2-CG1 4.07Å; M355-I361 HydrophobicContact CE-CD1 3.71Å; M355-I361 HydrophobicContact CG-CD1 4.14Å; I361-Y363 HydrophobicContact CG2-CE1 4.44Å; I361-Y363 HydrophobicContact CG2-CE2 4.09Å
362G94.4Very high91.1Very high0 Ų027 Ų270%013%0.132CC..EExtended strand (participates in β ladder)trans-99.1121175.500000110.9G101 M336 I337 S338G101-G362 WeakPolarHBondContact O-CA 3.35Å; M336-G362 PolarHBondContact O-N 2.98Å; I337-G362 CarbonylContact C-O 3.53Å; I337-G362 WeakPolarHBondContact CA-O 3.46Å; S338-G362 PolarHBondContact N-O 2.94Å
363Y92.2Very high90.9Very high1 Ų131 Ų310%0.00415%0.153CC..EExtended strand (participates in β ladder)trans-84.4139.8178.4-66.2-85.6000112.1L100 G101 Y113 P153 L164 V166 S338 L342 E351 I361L100-Y363 HydrophobicContact CB-CE2 4.22Å; L100-Y363 HydrophobicContact CD2-CE2 4.08Å; G101-Y363 WeakPolarHBondContact O-CD2 3.35Å; G101-Y363 PolarHBondContact O-N 3.46Å; Y113-Y363 WeakPolarHBondContact CE1-O 3.3Å; Y113-Y363 PolarHBondContact OH-O 2.83Å; P153-Y363 HydrophobicContact CB-CD2 4.23Å; P153-Y363 HydrophobicContact CB-CG 4.2Å; P153-Y363 HydrophobicContact CG-CG 4.49Å; L164-Y363 HydrophobicContact CD2-CD2 3.85Å; L164-Y363 HydrophobicContact CD2-CE2 3.82Å; V166-Y363 WeakPolarHBondContact CG2-OH 3.35Å; S338-Y363 WeakPolarHBondContact O-CA 3.12Å; S338-Y363 VanDerWaalsContact OG-CD1 3.3Å; S338-Y363 WeakPolarHBondContact OG-CD1 3.39Å; S338-Y363 WeakPolarHBondContact OG-CE1 3.49Å; L342-Y363 HydrophobicContact CD1-CE1 4.03Å; E351-Y363 WeakPolarHBondContact OE1-CE1 3.49Å; E351-Y363 PolarHBondContact OE1-OH 3.2Å; E351-Y363 VanDerWaalsContact OE1-OH 3.09Å; E351-Y363 PolarHBondContact OE2-OH 2.96Å; I361-Y363 HydrophobicContact CG2-CE1 4.44Å; I361-Y363 HydrophobicContact CG2-CE2 4.09Å
364Y90.6Very high90.7Very high19 Ų1930.8 Ų30.88%0.07515%0.152CC..PPolyproline II helixtrans-62.3165.917282.6-47.6000113.1N151 P153 S338 G366 V368N151-Y364 HydrophobicContact CB-CE1 4.03Å; N151-Y364 WeakPolarHBondContact O-CE1 3.39Å; N151-Y364 PolarHBondContact O-OH 3.2Å; P153-Y364 WeakPolarHBondContact CD-O 3.37Å; S338-Y364 WeakPolarHBondContact O-CD1 3.32Å; S338-Y364 PolarHBondContact O-N 3.01Å; Y364-G366 VanDerWaalsContact CE2-CA 3.49Å; Y364-G366 VanDerWaalsContact CZ-CA 3.48Å; Y364-G366 PolarHBondContact O-N 2.91Å; Y364-V368 HydrophobicContact CE2-CG2 3.91Å
365S85.8Confident90.6Very high11 Ų1130.8 Ų30.88%0.07715%0.152CC..  trans-72.710.4-177.761.20000115.4D367 D374S365-D367 VanDerWaalsContact C-N 3.31Å; S365-D367 PolarHBondContact O-N 3.08Å; S365-D374 WeakPolarHBondContact CB-OD1 3.22Å; S365-D374 WeakPolarHBondContact CB-OD2 3.29Å; S365-D374 PolarHBondContact N-OD2 3.18Å; S365-D374 PolarHBondContact OG-OD1 2.76Å; S365-D374 PolarHBondContact OG-OD2 3.34Å
366G79.1Confident90.6Very high15 Ų1534 Ų3416%0.15517%0.166CC..SBendtrans81.71.7-178.400000115.2R150 Y364R150-G366 PolarHBondContact NH1-O 2.86Å; Y364-G366 VanDerWaalsContact CE2-CA 3.49Å; Y364-G366 VanDerWaalsContact CZ-CA 3.48Å; Y364-G366 PolarHBondContact O-N 2.91Å
367D80.7Confident90.6Very high36 Ų3636.2 Ų36.219%0.19318%0.184CC..  trans-130.6109175.7-174.5-8000111S365 R369 K370S365-D367 VanDerWaalsContact C-N 3.31Å; S365-D367 PolarHBondContact O-N 3.08Å; D367-R369 PolarHBondContact O-N 3.48Å; D367-R369 VanDerWaalsContact OD1-CB 3.26Å; D367-R369 WeakPolarHBondContact OD1-CB 3.46Å; D367-R369 WeakPolarHBondContact OD1-CG 3.44Å; D367-R369 IonicContact OD1-CZ 3.51Å; D367-R369 PolarHBondContact OD1-N 2.73Å; D367-R369 IonicContact OD1-NE 3.92Å; D367-R369 PolarHBondContact OD1-NE 2.9Å; D367-R369 IonicContact OD1-NH2 2.87Å; D367-R369 IonicContact OD2-CZ 2.76Å; D367-R369 VanDerWaalsContact OD2-CZ 3.32Å; D367-R369 IonicContact OD2-NE 2.76Å; D367-R369 PolarHBondContact OD2-NE 3.02Å; D367-R369 VanDerWaalsContact OD2-NE 3.11Å; D367-R369 IonicContact OD2-NH2 3.6Å; D367-R369 PolarHBondContact OD2-NH2 3.06Å; D367-K370 HydrophobicContact CB-CD 4.33Å; D367-K370 HydrophobicContact CB-CG 4.34Å; D367-K370 WeakPolarHBondContact O-CB 3.15Å; D367-K370 PolarHBondContact O-N 2.84Å
368V80.5Confident90.5Very high65 Ų6535.4 Ų35.439%0.39418%0.181SC..G310 helixtrans-59.4-22.9-179.2-179.20000112.5Y364 K370 L371Y364-V368 HydrophobicContact CE2-CG2 3.91Å; V368-K370 PolarHBondContact O-N 3.4Å; V368-L371 HydrophobicContact CG1-CD2 4.49Å; V368-L371 WeakPolarHBondContact O-CB 3.32Å; V368-L371 PolarHBondContact O-N 2.89Å
369R80.9Confident90.5Very high194 Ų19441.1 Ų41.173%0.73221%0.206SC*.G310 helixtrans-66.6-23.7174.7-60.5171-66.7-173.62.4112.5D367D367-R369 PolarHBondContact O-N 3.48Å; D367-R369 VanDerWaalsContact OD1-CB 3.26Å; D367-R369 WeakPolarHBondContact OD1-CB 3.46Å; D367-R369 WeakPolarHBondContact OD1-CG 3.44Å; D367-R369 IonicContact OD1-CZ 3.51Å; D367-R369 PolarHBondContact OD1-N 2.73Å; D367-R369 IonicContact OD1-NE 3.92Å; D367-R369 PolarHBondContact OD1-NE 2.9Å; D367-R369 IonicContact OD1-NH2 2.87Å; D367-R369 IonicContact OD2-CZ 2.76Å; D367-R369 VanDerWaalsContact OD2-CZ 3.32Å; D367-R369 IonicContact OD2-NE 2.76Å; D367-R369 PolarHBondContact OD2-NE 3.02Å; D367-R369 VanDerWaalsContact OD2-NE 3.11Å; D367-R369 IonicContact OD2-NH2 3.6Å; D367-R369 PolarHBondContact OD2-NH2 3.06Å
370K87Confident90.5Very high95 Ų9541.1 Ų41.141%0.41321%0.206SC..G310 helixtrans-98.15.9177.6-60.2-178.1-177.1175.50112.9D367 V368 A372 D373 D374D367-K370 HydrophobicContact CB-CD 4.33Å; D367-K370 HydrophobicContact CB-CG 4.34Å; D367-K370 WeakPolarHBondContact O-CB 3.15Å; D367-K370 PolarHBondContact O-N 2.84Å; V368-K370 PolarHBondContact O-N 3.4Å; K370-A372 VanDerWaalsContact C-N 3.25Å; K370-A372 PolarHBondContact O-N 3.42Å; K370-D373 WeakPolarHBondContact O-CA 2.95Å; K370-D373 WeakPolarHBondContact O-CB 3.48Å; K370-D373 PolarHBondContact O-N 2.96Å; K370-D374 PolarHBondContact O-N 3.47Å
371L89.3Confident90.6Very high8 Ų839.4 Ų39.44%0.04220%0.199CC..Hα-helixtrans-57.3-36.8-175.1-175.862.8000112.9I337 Y339 V368 D373 D374 M375 F383 L389I337-L371 HydrophobicContact CD1-CD1 4.38Å; I337-L371 HydrophobicContact CG1-CD1 3.94Å; Y339-L371 HydrophobicContact CD1-CD1 4.3Å; Y339-L371 HydrophobicContact CD1-CD2 4.47Å; Y339-L371 HydrophobicContact CD2-CD2 4.03Å; Y339-L371 HydrophobicContact CE1-CD2 4.48Å; Y339-L371 HydrophobicContact CE2-CD2 4.02Å; Y339-L371 HydrophobicContact CG-CD1 4.07Å; Y339-L371 HydrophobicContact CG-CD2 4.26Å; V368-L371 HydrophobicContact CG1-CD2 4.49Å; V368-L371 WeakPolarHBondContact O-CB 3.32Å; V368-L371 PolarHBondContact O-N 2.89Å; L371-D373 VanDerWaalsContact C-N 3.35Å; L371-D373 PolarHBondContact O-N 3.34Å; L371-D374 WeakPolarHBondContact O-CB 3.46Å; L371-D374 PolarHBondContact O-N 2.74Å; L371-M375 HydrophobicContact CD1-CG 4.33Å; L371-M375 HydrophobicContact CD1-SD 4.49Å; L371-M375 HydrophobicContact CG-CG 4.41Å; L371-M375 HydrophobicContact CG-SD 4.13Å; L371-M375 WeakPolarHBondContact O-CB 3.41Å; L371-M375 VanDerWaalsContact O-CG 3.29Å; L371-M375 WeakPolarHBondContact O-CG 3.44Å; L371-M375 PolarHBondContact O-N 2.82Å; L371-F383 HydrophobicContact CD2-CE2 4.43Å; L371-L389 HydrophobicContact CD2-CD2 3.59Å
372A89.9Confident90.7Very high32 Ų3239.5 Ų39.526%0.26420%0.2SC..Hα-helixtrans-61.5-41.917400000112K370 D374 M375 K376K370-A372 VanDerWaalsContact C-N 3.25Å; K370-A372 PolarHBondContact O-N 3.42Å; A372-D374 VanDerWaalsContact C-N 3.32Å; A372-D374 PolarHBondContact O-N 3.01Å; A372-M375 PolarHBondContact O-N 2.98Å; A372-K376 WeakPolarHBondContact O-CB 3.47Å; A372-K376 VanDerWaalsContact O-CG 3.29Å; A372-K376 WeakPolarHBondContact O-CG 3.36Å; A372-K376 PolarHBondContact O-N 2.91Å
373D91.7Very high90.8Very high87 Ų8739.6 Ų39.647%0.46520%0.2SC..Hα-helixtrans-68.9-32.3176.2-64.7-26.3000112.1R103 K370 L371 K376 A377R103-D373 PolarHBondContact NH1-O 3.19Å; K370-D373 WeakPolarHBondContact O-CA 2.95Å; K370-D373 WeakPolarHBondContact O-CB 3.48Å; K370-D373 PolarHBondContact O-N 2.96Å; L371-D373 VanDerWaalsContact C-N 3.35Å; L371-D373 PolarHBondContact O-N 3.34Å; D373-K376 IonicContact OD1-NZ 3.94Å; D373-A377 WeakPolarHBondContact O-CB 3.03Å; D373-A377 PolarHBondContact O-N 3.12Å
374D92.2Very high90.9Very high1 Ų139.6 Ų39.61%0.00520%0.2CC..Hα-helixtrans-66.6-44.5171.9-69-38.3000112.1R103 I337 S365 K370 L371 A372 A377 L378R103-D374 IonicContact CZ-OD1 3.12Å; R103-D374 IonicContact NE-OD1 3.4Å; R103-D374 VanDerWaalsContact NH1-CA 3.34Å; R103-D374 IonicContact NH1-OD1 3.41Å; R103-D374 PolarHBondContact NH1-OD1 2.8Å; I337-D374 HydrophobicContact CD1-CB 4.4Å; S365-D374 WeakPolarHBondContact CB-OD1 3.22Å; S365-D374 WeakPolarHBondContact CB-OD2 3.29Å; S365-D374 PolarHBondContact N-OD2 3.18Å; S365-D374 PolarHBondContact OG-OD1 2.76Å; S365-D374 PolarHBondContact OG-OD2 3.34Å; K370-D374 PolarHBondContact O-N 3.47Å; L371-D374 WeakPolarHBondContact O-CB 3.46Å; L371-D374 PolarHBondContact O-N 2.74Å; A372-D374 VanDerWaalsContact C-N 3.32Å; A372-D374 PolarHBondContact O-N 3.01Å; D374-A377 PolarHBondContact O-N 3.45Å; D374-L378 VanDerWaalsContact O-CB 3.3Å; D374-L378 WeakPolarHBondContact O-CB 3.22Å; D374-L378 PolarHBondContact O-N 3.41Å
375M95Very high90.9Very high0 Ų038.7 Ų38.70%020%0.197CC..Hα-helixtrans-71-35.5178.2-68179.876.600112.4I337 L371 A372 A377 L378 K379 P380 F383 F445 L449I337-M375 HydrophobicContact CB-CG 4.42Å; I337-M375 HydrophobicContact CG1-CG 4.1Å; I337-M375 HydrophobicContact CG2-CE 4.13Å; I337-M375 HydrophobicContact CG2-CG 4.33Å; I337-M375 HydrophobicContact CG2-SD 4.39Å; L371-M375 HydrophobicContact CD1-CG 4.33Å; L371-M375 HydrophobicContact CD1-SD 4.49Å; L371-M375 HydrophobicContact CG-CG 4.41Å; L371-M375 HydrophobicContact CG-SD 4.13Å; L371-M375 WeakPolarHBondContact O-CB 3.41Å; L371-M375 VanDerWaalsContact O-CG 3.29Å; L371-M375 WeakPolarHBondContact O-CG 3.44Å; L371-M375 PolarHBondContact O-N 2.82Å; A372-M375 PolarHBondContact O-N 2.98Å; M375-A377 VanDerWaalsContact C-N 3.3Å; M375-A377 PolarHBondContact O-N 2.71Å; M375-L378 PolarHBondContact O-N 3.43Å; M375-K379 WeakPolarHBondContact O-CA 3.41Å; M375-K379 PolarHBondContact O-N 3.04Å; M375-P380 HydrophobicContact CB-CG 4.31Å; M375-P380 HydrophobicContact CE-CG 3.74Å; M375-P380 HydrophobicContact CG-CG 4.19Å; M375-P380 WeakPolarHBondContact O-CD 3.49Å; M375-F383 HydrophobicContact CE-CB 4.3Å; M375-F383 HydrophobicContact CE-CD1 3.85Å; M375-F383 HydrophobicContact CE-CD2 3.96Å; M375-F383 HydrophobicContact CE-CE1 4.06Å; M375-F383 HydrophobicContact CE-CE2 4.13Å; M375-F383 HydrophobicContact CE-CG 3.8Å; M375-F383 HydrophobicContact CE-CZ 4.19Å; M375-F383 HydrophobicContact SD-CD2 4.41Å; M375-F383 HydrophobicContact SD-CE1 4.4Å; M375-F383 HydrophobicContact SD-CE2 4.03Å; M375-F383 HydrophobicContact SD-CZ 4.03Å; M375-F445 HydrophobicContact CE-CB 4.08Å; M375-F445 HydrophobicContact CE-CD1 3.87Å; M375-F445 HydrophobicContact CE-CG 4.48Å; M375-F445 HydrophobicContact SD-CD1 3.71Å; M375-F445 HydrophobicContact SD-CE1 4.46Å; M375-L449 HydrophobicContact CE-CD1 4.08Å; M375-L449 HydrophobicContact CE-CD2 4.19Å
376K94.4Very high90.9Very high68 Ų6840 Ų4030%0.29620%0.204SC..Hα-helixtrans-58-42.8170.9-79.4172.6-170.7169.90112.2A372 D373 K379 A443 E444A372-K376 WeakPolarHBondContact O-CB 3.47Å; A372-K376 VanDerWaalsContact O-CG 3.29Å; A372-K376 WeakPolarHBondContact O-CG 3.36Å; A372-K376 PolarHBondContact O-N 2.91Å; D373-K376 IonicContact OD1-NZ 3.94Å; K376-K379 WeakPolarHBondContact O-CG 3.36Å; K376-A443 WeakPolarHBondContact CG-O 3.45Å; K376-E444 VanDerWaalsContact CE-CA 3.48Å; K376-E444 VanDerWaalsContact CE-OE1 3.3Å; K376-E444 WeakPolarHBondContact CE-OE1 3.46Å; K376-E444 WeakPolarHBondContact CE-OE2 3.26Å; K376-E444 IonicContact NZ-OE1 3.54Å; K376-E444 PolarHBondContact NZ-OE1 3.34Å; K376-E444 IonicContact NZ-OE2 3Å; K376-E444 PolarHBondContact NZ-OE2 3.39Å
377A94.4Very high90.9Very high48 Ų4839.7 Ų39.740%0.39720%0.2SC..Hα-helixtrans-74.4-41.6-179.900000112Y113 D373 D374 M375Y113-A377 HydrophobicContact CD2-CB 4.15Å; Y113-A377 HydrophobicContact CE2-CB 4.01Å; D373-A377 WeakPolarHBondContact O-CB 3.03Å; D373-A377 PolarHBondContact O-N 3.12Å; D374-A377 PolarHBondContact O-N 3.45Å; M375-A377 VanDerWaalsContact C-N 3.3Å; M375-A377 PolarHBondContact O-N 2.71Å
378L95.6Very high90.7Very high12 Ų1245.8 Ų45.86%0.06322%0.22CC..Hα-helixtrans-75.9-37.6-177.6-17357.7000113Y113 W115 I335 I337 D374 M375 P380Y113-L378 HydrophobicContact CD1-CD1 3.83Å; Y113-L378 HydrophobicContact CD2-CB 4.06Å; Y113-L378 HydrophobicContact CD2-CD1 4.03Å; Y113-L378 HydrophobicContact CE1-CB 4.48Å; Y113-L378 HydrophobicContact CE1-CD1 3.76Å; Y113-L378 HydrophobicContact CE1-CD2 4.39Å; Y113-L378 HydrophobicContact CE1-CG 4.43Å; Y113-L378 HydrophobicContact CE2-CB 3.42Å; Y113-L378 VanDerWaalsContact CE2-CB 3.42Å; Y113-L378 HydrophobicContact CE2-CD1 3.96Å; Y113-L378 HydrophobicContact CE2-CG 4.19Å; Y113-L378 HydrophobicContact CG-CD1 3.97Å; W115-L378 HydrophobicContact CH2-CD1 3.85Å; W115-L378 HydrophobicContact CZ2-CD1 3.69Å; I335-L378 HydrophobicContact CG2-CD1 3.65Å; I335-L378 HydrophobicContact CG2-CD2 4.08Å; I335-L378 HydrophobicContact CG2-CG 3.75Å; I337-L378 HydrophobicContact CB-CD2 3.89Å; I337-L378 HydrophobicContact CD1-CD2 3.62Å; I337-L378 HydrophobicContact CG1-CD2 4.35Å; D374-L378 VanDerWaalsContact O-CB 3.3Å; D374-L378 WeakPolarHBondContact O-CB 3.22Å; D374-L378 PolarHBondContact O-N 3.41Å; M375-L378 PolarHBondContact O-N 3.43Å; L378-P380 HydrophobicContact CD2-CB 4.21Å; L378-P380 HydrophobicContact CG-CB 4.46Å
379K97Very high90.8Very high121 Ų12143.9 Ų43.953%0.52621%0.208SC..  trans51.360.3-168.5-56.4-177.9-179.7177.80112.1M375 K376 N448M375-K379 WeakPolarHBondContact O-CA 3.41Å; M375-K379 PolarHBondContact O-N 3.04Å; K376-K379 WeakPolarHBondContact O-CG 3.36Å; K379-N448 HydrophobicContact CB-CB 4.03Å; K379-N448 WeakPolarHBondContact O-CB 3.32Å; K379-N448 PolarHBondContact O-ND2 3.29Å
380P97.8Very high91Very high0 Ų034.7 Ų34.70%017%0.173CC..  trans-64.7151.1-176.729.9-34.2000111.4I335 I337 M375 L378 N448 L449I335-P380 CarbonylContact O-C 3.47Å; I335-P380 WeakPolarHBondContact O-CA 3.41Å; I335-P380 WeakPolarHBondContact O-CB 3.31Å; I337-P380 HydrophobicContact CB-CB 4.13Å; I337-P380 HydrophobicContact CB-CG 4.17Å; I337-P380 HydrophobicContact CG2-CB 4.25Å; I337-P380 HydrophobicContact CG2-CG 4.14Å; M375-P380 HydrophobicContact CB-CG 4.31Å; M375-P380 HydrophobicContact CE-CG 3.74Å; M375-P380 HydrophobicContact CG-CG 4.19Å; M375-P380 WeakPolarHBondContact O-CD 3.49Å; L378-P380 HydrophobicContact CD2-CB 4.21Å; L378-P380 HydrophobicContact CG-CB 4.46Å; P380-N448 CarbonylContact O-C 3.54Å; P380-L449 HydrophobicContact CB-CD2 4.35Å; P380-L449 HydrophobicContact CG-CD2 3.99Å; P380-L449 WeakPolarHBondContact O-CD2 3.34Å; P380-L449 PolarHBondContact O-N 2.96Å
381T97.8Very high90.6Very high14 Ų1432.8 Ų32.89%0.08617%0.167CC..SBendtrans-93.4-32.3167.858.50000111.5D334 I335 N448 S450 L451D334-T381 WeakPolarHBondContact CA-OG1 3.5Å; D334-T381 WeakPolarHBondContact CB-OG1 3.39Å; D334-T381 VanDerWaalsContact OD1-CB 3.32Å; D334-T381 WeakPolarHBondContact OD1-CB 3.29Å; D334-T381 PolarHBondContact OD1-OG1 3.17Å; I335-T381 PolarHBondContact N-OG1 3.22Å; I335-T381 PolarHBondContact O-N 3.36Å; I335-T381 PolarHBondContact O-OG1 2.73Å; T381-N448 WeakPolarHBondContact CA-O 3.5Å; T381-N448 VanDerWaalsContact CG2-ND2 3.3Å; T381-N448 WeakPolarHBondContact CG2-ND2 3.39Å; T381-S450 PolarHBondContact O-N 2.88Å; T381-S450 PolarHBondContact O-OG 2.88Å; T381-L451 PolarHBondContact O-N 3.36Å; T381-L451 VanDerWaalsContact O-N 3.16Å
382L97.4Very high90.1Very high3 Ų339.1 Ų39.12%0.01619%0.191CC..EExtended strand (participates in β ladder)trans-111.9138178.7-77.472.6000111.7I330 D334 I335 M336 I337 M350 L354 L451I330-L382 HydrophobicContact CD1-CD2 3.72Å; I330-L382 HydrophobicContact CG1-CD2 4.02Å; D334-L382 HydrophobicContact CB-CD1 3.71Å; D334-L382 WeakPolarHBondContact OD1-CD1 3.41Å; I335-L382 PolarHBondContact O-N 2.92Å; M336-L382 WeakPolarHBondContact CA-O 3.46Å; M336-L382 HydrophobicContact CB-CB 4.02Å; M336-L382 HydrophobicContact CG-CB 4.15Å; I337-L382 PolarHBondContact N-O 2.74Å; M350-L382 HydrophobicContact CE-CD2 4.15Å; L354-L382 HydrophobicContact CD1-CD2 3.86Å; L382-L451 WeakPolarHBondContact CA-O 3.27Å; L382-L451 HydrophobicContact CD2-CD2 4.3Å; L382-L451 HydrophobicContact CG-CB 4.28Å; L382-L451 HydrophobicContact CG-CD2 4.32Å
383F96.7Very high89.9Confident2 Ų238.5 Ų38.51%0.00918%0.183CC..EExtended strand (participates in β ladder)trans-138.596.4178.5-179.8-148000111.9I337 Y339 L371 M375 V385 L389 L449 L451 I452 I453I337-F383 HydrophobicContact CG2-CB 4.34Å; I337-F383 HydrophobicContact CG2-CD2 3.43Å; I337-F383 VanDerWaalsContact CG2-CD2 3.43Å; I337-F383 HydrophobicContact CG2-CE2 4.07Å; I337-F383 HydrophobicContact CG2-CG 4.23Å; Y339-F383 HydrophobicContact CD1-CE2 4.32Å; Y339-F383 AromaticContact CE1-CD2 3.99Å; Y339-F383 HydrophobicContact CE1-CD2 3.99Å; Y339-F383 AromaticContact CE1-CE2 3.45Å; Y339-F383 HydrophobicContact CE1-CE2 3.45Å; Y339-F383 VanDerWaalsContact CE1-CE2 3.45Å; Y339-F383 AromaticContact CZ-CE2 3.85Å; L371-F383 HydrophobicContact CD2-CE2 4.43Å; M375-F383 HydrophobicContact CE-CB 4.3Å; M375-F383 HydrophobicContact CE-CD1 3.85Å; M375-F383 HydrophobicContact CE-CD2 3.96Å; M375-F383 HydrophobicContact CE-CE1 4.06Å; M375-F383 HydrophobicContact CE-CE2 4.13Å; M375-F383 HydrophobicContact CE-CG 3.8Å; M375-F383 HydrophobicContact CE-CZ 4.19Å; M375-F383 HydrophobicContact SD-CD2 4.41Å; M375-F383 HydrophobicContact SD-CE1 4.4Å; M375-F383 HydrophobicContact SD-CE2 4.03Å; M375-F383 HydrophobicContact SD-CZ 4.03Å; F383-V385 HydrophobicContact CD1-CB 4.43Å; F383-V385 HydrophobicContact CE1-CB 4.21Å; F383-V385 HydrophobicContact CE1-CG2 3.92Å; F383-V385 HydrophobicContact CE2-CB 4.47Å; F383-V385 HydrophobicContact CE2-CG2 4.39Å; F383-V385 HydrophobicContact CZ-CB 4.24Å; F383-V385 HydrophobicContact CZ-CG2 3.8Å; F383-L389 HydrophobicContact CE2-CD2 4.44Å; F383-L389 HydrophobicContact CZ-CD2 3.88Å; F383-L449 HydrophobicContact CB-CD2 3.6Å; F383-L449 HydrophobicContact CD1-CD1 4.31Å; F383-L451 PolarHBondContact N-O 2.89Å; F383-I452 HydrophobicContact CB-CG1 4.27Å; F383-I452 HydrophobicContact CD1-CD1 4.36Å; F383-I452 HydrophobicContact CD1-CG1 4.4Å; F383-I452 HydrophobicContact CD1-CG2 4.44Å; F383-I452 WeakPolarHBondContact O-CA 3.44Å; F383-I453 PolarHBondContact O-N 2.84Å
384P94.6Very high89.6Confident0 Ų035.7 Ų35.70%017%0.166CC..EExtended strand (participates in β ladder)trans-67.9132.5167.629.2-33.5000109.6M336 Y339 L340 F346 E347 M350 I453M336-P384 HydrophobicContact CG-CG 4.17Å; M336-P384 HydrophobicContact SD-CG 3.88Å; Y339-P384 WeakPolarHBondContact CE1-O 3.23Å; Y339-P384 PolarHBondContact OH-O 3.42Å; L340-P384 HydrophobicContact CD1-CB 3.97Å; L340-P384 HydrophobicContact CD1-CG 4.46Å; F346-P384 HydrophobicContact CE1-CB 4.21Å; F346-P384 HydrophobicContact CZ-CB 3.92Å; E347-P384 VanDerWaalsContact OE2-CG 3.28Å; E347-P384 WeakPolarHBondContact OE2-CG 3.4Å; M350-P384 HydrophobicContact CG-CB 4.29Å; P384-I453 CarbonylContact C-O 3.51Å; P384-I453 WeakPolarHBondContact CA-O 3.43Å
385V91.3Very high89.1Confident0 Ų038.7 Ų38.70%018%0.183CC..EExtended strand (participates in β ladder)trans-141.4146.1-170.275.70000113Y339 F383 L389 M390 I452 I453 S454 G455Y339-V385 WeakPolarHBondContact OH-CA 3.26Å; F383-V385 HydrophobicContact CD1-CB 4.43Å; F383-V385 HydrophobicContact CE1-CB 4.21Å; F383-V385 HydrophobicContact CE1-CG2 3.92Å; F383-V385 HydrophobicContact CE2-CB 4.47Å; F383-V385 HydrophobicContact CE2-CG2 4.39Å; F383-V385 HydrophobicContact CZ-CB 4.24Å; F383-V385 HydrophobicContact CZ-CG2 3.8Å; V385-L389 HydrophobicContact CG2-CB 4.17Å; V385-L389 HydrophobicContact CG2-CD2 4.1Å; V385-L389 HydrophobicContact CG2-CG 4.29Å; V385-M390 HydrophobicContact CB-CG 4.31Å; V385-M390 HydrophobicContact CG1-CE 4.38Å; V385-M390 HydrophobicContact CG1-CG 3.67Å; V385-M390 HydrophobicContact CG1-SD 3.53Å; V385-M390 VanDerWaalsContact CG1-SD 3.53Å; V385-M390 HydrophobicContact CG2-CG 3.62Å; V385-I452 HydrophobicContact CB-CG2 4.38Å; V385-I452 HydrophobicContact CG1-CG2 3.54Å; V385-I453 PolarHBondContact N-O 2.76Å; V385-S454 VanDerWaalsContact O-CA 3.26Å; V385-S454 WeakPolarHBondContact O-CA 3.45Å; V385-S454 PolarHBondContact O-OG 2.9Å; V385-G455 PolarHBondContact O-N 3.45Å
386V84.6Confident88.5Confident39 Ų3942.6 Ų42.624%0.23620%0.201CC..  trans-102.2147.9173.1-66.60000111L340 R388 L389 M390L340-V386 HydrophobicContact CD1-CG1 4.42Å; L340-V386 HydrophobicContact CD2-CG1 3.85Å; L340-V386 HydrophobicContact CD2-CG2 4.38Å; V386-R388 PolarHBondContact O-N 3.39Å; V386-R388 VanDerWaalsContact O-N 3.1Å; V386-L389 HydrophobicContact CG2-CB 4.22Å; V386-L389 PolarHBondContact O-N 2.81Å; V386-M390 PolarHBondContact O-N 3.06Å
387P80.2Confident88.1Confident9 Ų940.1 Ų40.16%0.05819%0.191CC..Hα-helixtrans-53.1-38.5-175.9-25.227.6000113.7L389 M390 N391 G455 A457 P458 V459P387-L389 VanDerWaalsContact C-N 3.27Å; P387-L389 PolarHBondContact O-N 2.95Å; P387-M390 WeakPolarHBondContact O-CB 3.38Å; P387-M390 PolarHBondContact O-N 3.08Å; P387-N391 VanDerWaalsContact O-CG 3.32Å; P387-N391 PolarHBondContact O-N 2.94Å; P387-N391 PolarHBondContact O-ND2 3.43Å; P387-G455 VanDerWaalsContact CD-O 3.28Å; P387-G455 WeakPolarHBondContact CD-O 3.42Å; P387-A457 HydrophobicContact CG-CB 3.87Å; P387-A457 WeakPolarHBondContact CG-O 3.32Å; P387-P458 WeakPolarHBondContact CB-O 3.5Å; P387-P458 WeakPolarHBondContact CG-O 3.36Å; P387-V459 HydrophobicContact CB-CG2 3.77Å; P387-V459 HydrophobicContact CG-CG2 3.57Å
388R76.5Confident87.5Confident164 Ų16439.2 Ų39.262%0.61918%0.179SC*.Hα-helixtrans-56-40.9177.8-175.2178.6-177.7-177.43.2112.4V386 R392 L696V386-R388 PolarHBondContact O-N 3.39Å; V386-R388 VanDerWaalsContact O-N 3.1Å; R388-R392 PolarHBondContact O-N 3.17Å; R388-L696 VanDerWaalsContact NH1-CD1 3.33Å
389L81.6Confident86.8Confident25 Ų2540.8 Ų40.813%0.13119%0.187CC..Hα-helixtrans-74-38.4177.5-178.659.1000110.8Y339 L371 F383 V385 V386 P387 R392 V393Y339-L389 HydrophobicContact CE2-CD2 3.84Å; Y339-L389 WeakPolarHBondContact OH-CD2 3.39Å; L371-L389 HydrophobicContact CD2-CD2 3.59Å; F383-L389 HydrophobicContact CE2-CD2 4.44Å; F383-L389 HydrophobicContact CZ-CD2 3.88Å; V385-L389 HydrophobicContact CG2-CB 4.17Å; V385-L389 HydrophobicContact CG2-CD2 4.1Å; V385-L389 HydrophobicContact CG2-CG 4.29Å; V386-L389 HydrophobicContact CG2-CB 4.22Å; V386-L389 PolarHBondContact O-N 2.81Å; P387-L389 VanDerWaalsContact C-N 3.27Å; P387-L389 PolarHBondContact O-N 2.95Å; L389-R392 PolarHBondContact O-N 3.22Å; L389-V393 HydrophobicContact CD1-CG2 4.45Å; L389-V393 WeakPolarHBondContact O-CG2 3.15Å; L389-V393 PolarHBondContact O-N 3.11Å
390M85.3Confident86.1Confident0 Ų042.1 Ų42.10%019%0.193CC..Hα-helixtrans-59.7-48.5176-61.5-176.876.400111.9V385 V386 P387 R392 V393 Y394 S454 V459 V463 L464 F467 V475V385-M390 HydrophobicContact CB-CG 4.31Å; V385-M390 HydrophobicContact CG1-CE 4.38Å; V385-M390 HydrophobicContact CG1-CG 3.67Å; V385-M390 HydrophobicContact CG1-SD 3.53Å; V385-M390 VanDerWaalsContact CG1-SD 3.53Å; V385-M390 HydrophobicContact CG2-CG 3.62Å; V386-M390 PolarHBondContact O-N 3.06Å; P387-M390 WeakPolarHBondContact O-CB 3.38Å; P387-M390 PolarHBondContact O-N 3.08Å; M390-R392 VanDerWaalsContact C-N 3.32Å; M390-R392 PolarHBondContact O-N 3.01Å; M390-V393 PolarHBondContact O-N 3.12Å; M390-Y394 WeakPolarHBondContact O-CB 3.26Å; M390-Y394 PolarHBondContact O-N 3.22Å; M390-S454 PolarHBondContact SD-OG 3.29Å; M390-S454 VanDerWaalsContact SD-OG 3.37Å; M390-V459 HydrophobicContact CE-CG1 4.35Å; M390-V459 HydrophobicContact SD-CG1 4.08Å; M390-V459 HydrophobicContact SD-CG2 3.88Å; M390-V463 HydrophobicContact CB-CG1 3.68Å; M390-V463 HydrophobicContact CE-CG1 4.37Å; M390-L464 HydrophobicContact CE-CD2 4.21Å; M390-F467 HydrophobicContact CB-CD2 4.39Å; M390-F467 HydrophobicContact CB-CE2 3.7Å; M390-F467 HydrophobicContact CB-CZ 3.85Å; M390-F467 HydrophobicContact CE-CB 3.96Å; M390-F467 HydrophobicContact CE-CD1 3.8Å; M390-F467 HydrophobicContact CE-CD2 3.55Å; M390-F467 HydrophobicContact CE-CE1 4.18Å; M390-F467 HydrophobicContact CE-CE2 3.99Å; M390-F467 HydrophobicContact CE-CG 3.48Å; M390-F467 VanDerWaalsContact CE-CG 3.48Å; M390-F467 HydrophobicContact CE-CZ 4.29Å; M390-F467 HydrophobicContact CG-CE1 4.22Å; M390-F467 HydrophobicContact CG-CE2 4.12Å; M390-F467 HydrophobicContact CG-CZ 3.91Å; M390-F467 WeakPolarHBondContact O-CE2 3.49Å; M390-V475 HydrophobicContact CE-CG1 4.32Å
391N80.1Confident85.3Confident56 Ų5643 Ų4330%0.29920%0.198SC..Hα-helixtrans-58.5-44.9176.1-67.7-20.9000111P387 V393 Y394 D395 V463P387-N391 VanDerWaalsContact O-CG 3.32Å; P387-N391 PolarHBondContact O-N 2.94Å; P387-N391 PolarHBondContact O-ND2 3.43Å; N391-V393 VanDerWaalsContact C-N 3.34Å; N391-V393 PolarHBondContact O-N 3.4Å; N391-Y394 WeakPolarHBondContact O-CB 3.46Å; N391-Y394 PolarHBondContact O-N 2.92Å; N391-D395 WeakPolarHBondContact O-CB 3.31Å; N391-D395 PolarHBondContact O-N 3.44Å; N391-V463 WeakPolarHBondContact OD1-CG2 3.41Å
392R78.8Confident84.4Confident141 Ų14145.6 Ų45.653%0.53222%0.217SC..Hα-helixtrans-59.2-43.3176.7-177.8178.2177.8164.11.8112.5R388 L389 M390 Q396R388-R392 PolarHBondContact O-N 3.17Å; L389-R392 PolarHBondContact O-N 3.22Å; M390-R392 VanDerWaalsContact C-N 3.32Å; M390-R392 PolarHBondContact O-N 3.01Å; R392-Q396 WeakPolarHBondContact O-CB 3.31Å; R392-Q396 WeakPolarHBondContact O-CG 3.38Å; R392-Q396 PolarHBondContact O-N 3Å; R392-Q396 VanDerWaalsContact O-N 3.13Å
393V85.4Confident83.4Confident18 Ų1848.8 Ų48.811%0.10925%0.251CS..Hα-helixtrans-65.7-44.5176.9172.60000110.4L389 M390 N391 Q396 V397 F445 F466 F467L389-V393 HydrophobicContact CD1-CG2 4.45Å; L389-V393 WeakPolarHBondContact O-CG2 3.15Å; L389-V393 PolarHBondContact O-N 3.11Å; M390-V393 PolarHBondContact O-N 3.12Å; N391-V393 VanDerWaalsContact C-N 3.34Å; N391-V393 PolarHBondContact O-N 3.4Å; V393-Q396 PolarHBondContact O-N 2.65Å; V393-V397 WeakPolarHBondContact O-CG2 3.2Å; V393-V397 PolarHBondContact O-N 2.9Å; V393-V397 VanDerWaalsContact O-N 3.08Å; V393-F445 HydrophobicContact CB-CZ 4.39Å; V393-F445 HydrophobicContact CG1-CE2 4.17Å; V393-F445 HydrophobicContact CG1-CZ 3.63Å; V393-F445 HydrophobicContact CG2-CE1 4.12Å; V393-F445 HydrophobicContact CG2-CZ 3.77Å; V393-F466 HydrophobicContact CG1-CE1 4.34Å; V393-F467 HydrophobicContact CB-CE2 4.36Å; V393-F467 HydrophobicContact CB-CZ 3.9Å; V393-F467 HydrophobicContact CG1-CE2 4.4Å; V393-F467 HydrophobicContact CG1-CZ 3.97Å; V393-F467 HydrophobicContact CG2-CZ 4.42Å
394Y85.1Confident82.7Confident28 Ų2852 Ų5211%0.1127%0.268CS..Hα-helixtrans-55-54.8176.2179.7-105.2000111.5M390 N391 Q396 V397 Q398 E462 V463 F466M390-Y394 WeakPolarHBondContact O-CB 3.26Å; M390-Y394 PolarHBondContact O-N 3.22Å; N391-Y394 WeakPolarHBondContact O-CB 3.46Å; N391-Y394 PolarHBondContact O-N 2.92Å; Y394-Q396 VanDerWaalsContact C-N 3.33Å; Y394-Q396 PolarHBondContact O-N 2.96Å; Y394-V397 PolarHBondContact O-N 3.24Å; Y394-V397 VanDerWaalsContact O-N 3.12Å; Y394-Q398 HydrophobicContact CD1-CG 4.17Å; Y394-Q398 HydrophobicContact CD2-CG 4.38Å; Y394-Q398 HydrophobicContact CE1-CG 3.75Å; Y394-Q398 HydrophobicContact CE2-CG 3.97Å; Y394-Q398 VanDerWaalsContact CE2-NE2 3.3Å; Y394-Q398 HydrophobicContact CG-CG 4.46Å; Y394-Q398 WeakPolarHBondContact O-CG 3.44Å; Y394-Q398 PolarHBondContact O-N 2.93Å; Y394-Q398 PolarHBondContact OH-NE2 2.92Å; Y394-E462 HydrophobicContact CE2-CG 4.4Å; Y394-E462 PolarHBondContact OH-OE1 3.47Å; Y394-V463 HydrophobicContact CD1-CG2 4.03Å; Y394-V463 HydrophobicContact CD2-CG2 4.37Å; Y394-V463 HydrophobicContact CG-CG2 3.93Å; Y394-F466 HydrophobicContact CD2-CB 3.73Å; Y394-F466 AromaticContact CD2-CD1 3.57Å; Y394-F466 HydrophobicContact CD2-CD1 3.57Å; Y394-F466 AromaticContact CD2-CD2 3.99Å; Y394-F466 HydrophobicContact CD2-CD2 3.99Å; Y394-F466 HydrophobicContact CD2-CE1 4.18Å; Y394-F466 AromaticContact CD2-CG 3.46Å; Y394-F466 HydrophobicContact CD2-CG 3.46Å; Y394-F466 VanDerWaalsContact CD2-CG 3.46Å; Y394-F466 HydrophobicContact CE2-CB 3.85Å; Y394-F466 HydrophobicContact CE2-CD1 4.44Å; Y394-F466 HydrophobicContact CE2-CD2 4.17Å; Y394-F466 AromaticContact CE2-CG 3.89Å; Y394-F466 HydrophobicContact CE2-CG 3.89Å; Y394-F466 HydrophobicContact CG-CD1 4.42Å
395D80.5Confident82.1Confident65 Ų6558.1 Ų58.135%0.34831%0.305SS..Hα-helixtrans-60.1-42.2-177.9-65.4-21.1000111.9N391 V397 Q398 L399N391-D395 WeakPolarHBondContact O-CB 3.31Å; N391-D395 PolarHBondContact O-N 3.44Å; D395-V397 VanDerWaalsContact C-N 3.33Å; D395-V397 PolarHBondContact O-N 3.37Å; D395-Q398 PolarHBondContact O-N 3.42Å; D395-L399 WeakPolarHBondContact O-CB 3.41Å; D395-L399 WeakPolarHBondContact O-CG 3.26Å; D395-L399 PolarHBondContact O-N 2.84Å
396Q83.1Confident81.7Confident81 Ų8160 Ų6038%0.37932%0.315SS..Hα-helixtrans-64.2-36.8177.9-74-66.9-43.100112.5R392 V393 Y394 K400R392-Q396 WeakPolarHBondContact O-CB 3.31Å; R392-Q396 WeakPolarHBondContact O-CG 3.38Å; R392-Q396 PolarHBondContact O-N 3Å; R392-Q396 VanDerWaalsContact O-N 3.13Å; V393-Q396 PolarHBondContact O-N 2.65Å; Y394-Q396 VanDerWaalsContact C-N 3.33Å; Y394-Q396 PolarHBondContact O-N 2.96Å; Q396-K400 WeakPolarHBondContact O-CG 2.83Å; Q396-K400 PolarHBondContact O-N 2.84Å
397V85.6Confident81.7Confident16 Ų1664.3 Ų64.310%0.09733%0.33CS..Hα-helixtrans-71.6-43.8174.7174.30000110.5V393 Y394 D395 L399 K400 V401 F411 V441 F466V393-V397 WeakPolarHBondContact O-CG2 3.2Å; V393-V397 PolarHBondContact O-N 2.9Å; V393-V397 VanDerWaalsContact O-N 3.08Å; Y394-V397 PolarHBondContact O-N 3.24Å; Y394-V397 VanDerWaalsContact O-N 3.12Å; D395-V397 VanDerWaalsContact C-N 3.33Å; D395-V397 PolarHBondContact O-N 3.37Å; V397-L399 VanDerWaalsContact C-N 3.33Å; V397-L399 PolarHBondContact O-N 3.15Å; V397-K400 PolarHBondContact O-N 2.82Å; V397-V401 HydrophobicContact CG1-CG2 4.29Å; V397-V401 WeakPolarHBondContact O-CB 3.39Å; V397-V401 VanDerWaalsContact O-CG2 3.27Å; V397-V401 WeakPolarHBondContact O-CG2 3.5Å; V397-V401 PolarHBondContact O-N 3.22Å; V397-F411 HydrophobicContact CG1-CE2 3.85Å; V397-F411 HydrophobicContact CG1-CZ 4Å; V397-V441 HydrophobicContact CG1-CG2 4.48Å; V397-V441 HydrophobicContact CG2-CG1 4.02Å; V397-F466 HydrophobicContact CB-CE2 4.32Å; V397-F466 HydrophobicContact CB-CZ 3.95Å; V397-F466 HydrophobicContact CG1-CE2 3.93Å; V397-F466 HydrophobicContact CG1-CZ 4Å; V397-F466 HydrophobicContact CG2-CZ 3.98Å
398Q82.5Confident81.9Confident30 Ų3066.5 Ų66.514%0.1434%0.339CS..Hα-helixtrans-60.1-41176.2-68.8-61.7-22.500112.2Y394 D395 V401 S402Y394-Q398 HydrophobicContact CD1-CG 4.17Å; Y394-Q398 HydrophobicContact CD2-CG 4.38Å; Y394-Q398 HydrophobicContact CE1-CG 3.75Å; Y394-Q398 HydrophobicContact CE2-CG 3.97Å; Y394-Q398 VanDerWaalsContact CE2-NE2 3.3Å; Y394-Q398 HydrophobicContact CG-CG 4.46Å; Y394-Q398 WeakPolarHBondContact O-CG 3.44Å; Y394-Q398 PolarHBondContact O-N 2.93Å; Y394-Q398 PolarHBondContact OH-NE2 2.92Å; D395-Q398 PolarHBondContact O-N 3.42Å; Q398-V401 PolarHBondContact O-N 3.23Å; Q398-S402 VanDerWaalsContact O-CB 3.22Å; Q398-S402 WeakPolarHBondContact O-CB 3.25Å; Q398-S402 PolarHBondContact O-N 2.88Å; Q398-S402 PolarHBondContact O-OG 3.05Å
399L80.9Confident82.4Confident45 Ų4562.8 Ų62.824%0.23633%0.327CS..Hα-helixtrans-59.3-49.3173.9-82.4170000112.4D395 V397 V401 S402 G403 F628D395-L399 WeakPolarHBondContact O-CB 3.41Å; D395-L399 WeakPolarHBondContact O-CG 3.26Å; D395-L399 PolarHBondContact O-N 2.84Å; V397-L399 VanDerWaalsContact C-N 3.33Å; V397-L399 PolarHBondContact O-N 3.15Å; L399-V401 VanDerWaalsContact C-N 3.26Å; L399-V401 PolarHBondContact O-N 3.11Å; L399-S402 PolarHBondContact O-OG 2.9Å; L399-S402 VanDerWaalsContact O-OG 3.12Å; L399-G403 PolarHBondContact O-N 2.98Å; L399-F628 HydrophobicContact CD1-CE2 3.77Å; L399-F628 HydrophobicContact CD1-CZ 3.75Å; L399-F628 HydrophobicContact CD2-CD1 4.26Å; L399-F628 HydrophobicContact CD2-CE1 3.34Å; L399-F628 HydrophobicContact CD2-CE2 3.83Å; L399-F628 HydrophobicContact CD2-CZ 3.14Å; L399-F628 HydrophobicContact CG-CE1 4.06Å; L399-F628 HydrophobicContact CG-CE2 3.93Å; L399-F628 HydrophobicContact CG-CZ 3.35Å
400K81.5Confident82.7Confident149 Ų14963 Ų6365%0.64833%0.329SS*.Hα-helixtrans-63.5-33.2-179.6-76.2176.1-179.41790112.8Q396 V397Q396-K400 WeakPolarHBondContact O-CG 2.83Å; Q396-K400 PolarHBondContact O-N 2.84Å; V397-K400 PolarHBondContact O-N 2.82Å
401V82.5Confident82.9Confident19 Ų1963.3 Ų63.312%0.11533%0.33CS..Hα-helixtrans-83.4-40.1-177.9172.50000111.7V397 Q398 L399 G403 N404 K408 F411V397-V401 HydrophobicContact CG1-CG2 4.29Å; V397-V401 WeakPolarHBondContact O-CB 3.39Å; V397-V401 VanDerWaalsContact O-CG2 3.27Å; V397-V401 WeakPolarHBondContact O-CG2 3.5Å; V397-V401 PolarHBondContact O-N 3.22Å; Q398-V401 PolarHBondContact O-N 3.23Å; L399-V401 VanDerWaalsContact C-N 3.26Å; L399-V401 PolarHBondContact O-N 3.11Å; V401-G403 PolarHBondContact O-N 2.9Å; V401-N404 PolarHBondContact O-N 3.01Å; V401-K408 VanDerWaalsContact CG1-CA 3.42Å; V401-K408 HydrophobicContact CG1-CB 4.01Å; V401-K408 HydrophobicContact CG1-CD 3.74Å; V401-K408 HydrophobicContact CG1-CG 4.49Å; V401-F411 HydrophobicContact CB-CG 4.44Å; V401-F411 HydrophobicContact CG1-CB 3.5Å; V401-F411 VanDerWaalsContact CG1-CB 3.5Å; V401-F411 HydrophobicContact CG1-CD1 4.02Å; V401-F411 HydrophobicContact CG1-CD2 4.36Å; V401-F411 HydrophobicContact CG1-CG 3.71Å; V401-F411 HydrophobicContact CG2-CB 4.37Å; V401-F411 HydrophobicContact CG2-CD2 3.83Å; V401-F411 HydrophobicContact CG2-CE2 4.28Å; V401-F411 HydrophobicContact CG2-CG 4.03Å
402S77.4Confident83.3Confident68 Ų6863.9 Ų63.948%0.47633%0.333SS..Hα-helixtrans-67.9-19.4-177.955.60000114.3Q398 L399 N404Q398-S402 VanDerWaalsContact O-CB 3.22Å; Q398-S402 WeakPolarHBondContact O-CB 3.25Å; Q398-S402 PolarHBondContact O-N 2.88Å; Q398-S402 PolarHBondContact O-OG 3.05Å; L399-S402 PolarHBondContact O-OG 2.9Å; L399-S402 VanDerWaalsContact O-OG 3.12Å; S402-N404 PolarHBondContact O-N 3.3Å; S402-N404 VanDerWaalsContact O-N 3.1Å
403G76.8Confident83.8Confident70 Ų7058.7 Ų58.772%0.72232%0.316SS*.THydrogen-bonded Turntrans-64.7-7.5173.400000115L399 V401L399-G403 PolarHBondContact O-N 2.98Å; V401-G403 PolarHBondContact O-N 2.9Å
404N81.5Confident83.9Confident70 Ų7057.9 Ų57.937%0.37431%0.31SS..SBendtrans-145.8118.5177.4180-44.9000110.9V401 S402 L406 K407 K408V401-N404 PolarHBondContact O-N 3.01Å; S402-N404 PolarHBondContact O-N 3.3Å; S402-N404 VanDerWaalsContact O-N 3.1Å; N404-L406 VanDerWaalsContact C-N 3.29Å; N404-L406 PolarHBondContact O-N 3.18Å; N404-L406 WeakPolarHBondContact OD1-CB 3.22Å; N404-L406 PolarHBondContact OD1-N 2.87Å; N404-K407 HydrophobicContact CB-CB 3.99Å; N404-K407 HydrophobicContact CB-CD 3.97Å; N404-K407 HydrophobicContact CB-CG 3.89Å; N404-K407 PolarHBondContact O-N 3.43Å; N404-K407 PolarHBondContact OD1-N 2.82Å; N404-K407 VanDerWaalsContact OD1-N 3.14Å; N404-K408 PolarHBondContact O-N 3.23Å
405V83.9Confident84.2Confident128 Ų12858.1 Ų58.178%0.77631%0.313SS*.Hα-helixtrans-55.4-41.3-176.3-178.40000112.5K408 F409V405-K408 PolarHBondContact O-N 2.94Å; V405-F409 WeakPolarHBondContact O-CB 3.35Å; V405-F409 PolarHBondContact O-N 3.16Å
406L82.3Confident84.6Confident40 Ų4063.7 Ų63.721%0.20933%0.329CS..Hα-helixtrans-67.9-43.7177.8-179.559.8000111.5L16 V19 V20 N404 K408 F409 I410L16-L406 HydrophobicContact CD1-CB 3.83Å; L16-L406 HydrophobicContact CD1-CD1 3.63Å; L16-L406 HydrophobicContact CD1-CD2 3.67Å; L16-L406 HydrophobicContact CD1-CG 3.89Å; V19-L406 HydrophobicContact CB-CD2 4.32Å; V19-L406 HydrophobicContact CG1-CD1 4.09Å; V19-L406 HydrophobicContact CG1-CD2 3.98Å; V19-L406 HydrophobicContact CG1-CG 4.4Å; V20-L406 HydrophobicContact CG2-CD1 3.88Å; N404-L406 VanDerWaalsContact C-N 3.29Å; N404-L406 PolarHBondContact O-N 3.18Å; N404-L406 WeakPolarHBondContact OD1-CB 3.22Å; N404-L406 PolarHBondContact OD1-N 2.87Å; L406-K408 VanDerWaalsContact C-N 3.29Å; L406-K408 PolarHBondContact O-N 3.48Å; L406-F409 PolarHBondContact O-N 3.03Å; L406-I410 HydrophobicContact CD1-CD1 3.99Å; L406-I410 HydrophobicContact CD1-CG1 4.22Å; L406-I410 HydrophobicContact CG-CD1 3.89Å; L406-I410 VanDerWaalsContact O-CG1 3.28Å; L406-I410 WeakPolarHBondContact O-CG1 3.37Å; L406-I410 PolarHBondContact O-N 3.17Å
407K83.6Confident84.9Confident128 Ų12859.9 Ų59.956%0.55731%0.311SS*.Hα-helixtrans-61.2-41.1176.1-68.7-173.2-177.4178.10111N404 I410 F411N404-K407 HydrophobicContact CB-CB 3.99Å; N404-K407 HydrophobicContact CB-CD 3.97Å; N404-K407 HydrophobicContact CB-CG 3.89Å; N404-K407 PolarHBondContact O-N 3.43Å; N404-K407 PolarHBondContact OD1-N 2.82Å; N404-K407 VanDerWaalsContact OD1-N 3.14Å; K407-I410 PolarHBondContact O-N 2.73Å; K407-F411 WeakPolarHBondContact O-CB 3.42Å; K407-F411 PolarHBondContact O-N 3.22Å
408K85.8Confident85Confident56 Ų5659.4 Ų59.424%0.24331%0.308CS..Hα-helixtrans-62.6-47.3175.8-175.557.7175.4159.50112.2V401 N404 V405 L406 I410 F411 D412V401-K408 VanDerWaalsContact CG1-CA 3.42Å; V401-K408 HydrophobicContact CG1-CB 4.01Å; V401-K408 HydrophobicContact CG1-CD 3.74Å; V401-K408 HydrophobicContact CG1-CG 4.49Å; N404-K408 PolarHBondContact O-N 3.23Å; V405-K408 PolarHBondContact O-N 2.94Å; L406-K408 VanDerWaalsContact C-N 3.29Å; L406-K408 PolarHBondContact O-N 3.48Å; K408-I410 PolarHBondContact O-N 3.09Å; K408-F411 PolarHBondContact O-N 2.95Å; K408-D412 WeakPolarHBondContact CD-OD2 3.35Å; K408-D412 VanDerWaalsContact CE-OD1 3.3Å; K408-D412 WeakPolarHBondContact CE-OD1 3.28Å; K408-D412 WeakPolarHBondContact CE-OD2 3.26Å; K408-D412 IonicContact NZ-OD1 2.86Å; K408-D412 PolarHBondContact NZ-OD1 2.97Å; K408-D412 IonicContact NZ-OD2 2.67Å; K408-D412 PolarHBondContact NZ-OD2 2.7Å; K408-D412 WeakPolarHBondContact O-CB 3.24Å; K408-D412 VanDerWaalsContact O-CG 3.23Å; K408-D412 PolarHBondContact O-N 2.97Å
409F86.1Confident85.4Confident86 Ų8658.7 Ų58.738%0.37731%0.309SS..Hα-helixtrans-57.9-48.2175.4177.5-99.2000112.6V20 V405 L406 F411 D412 L413V20-F409 HydrophobicContact CG1-CE1 4.04Å; V20-F409 HydrophobicContact CG1-CZ 4.34Å; V20-F409 HydrophobicContact CG2-CD1 4.4Å; V20-F409 HydrophobicContact CG2-CE1 4.35Å; V405-F409 WeakPolarHBondContact O-CB 3.35Å; V405-F409 PolarHBondContact O-N 3.16Å; L406-F409 PolarHBondContact O-N 3.03Å; F409-F411 VanDerWaalsContact C-N 3.35Å; F409-F411 PolarHBondContact O-N 2.65Å; F409-D412 PolarHBondContact O-N 3.21Å; F409-L413 HydrophobicContact CE1-CD2 4.28Å; F409-L413 HydrophobicContact CZ-CD2 4.39Å; F409-L413 WeakPolarHBondContact O-CB 3.17Å; F409-L413 PolarHBondContact O-N 3.03Å
410I87.3Confident85.7Confident30 Ų3059.4 Ų59.415%0.15431%0.311CS..Hα-helixtrans-62.9-43.6178.5-65.5167.7000110.6V19 T23 L406 K407 K408 L413 A414 W433 V437V19-I410 HydrophobicContact CG1-CD1 3.97Å; T23-I410 HydrophobicContact CG2-CB 4.47Å; T23-I410 HydrophobicContact CG2-CG1 3.98Å; T23-I410 HydrophobicContact CG2-CG2 4.29Å; L406-I410 HydrophobicContact CD1-CD1 3.99Å; L406-I410 HydrophobicContact CD1-CG1 4.22Å; L406-I410 HydrophobicContact CG-CD1 3.89Å; L406-I410 VanDerWaalsContact O-CG1 3.28Å; L406-I410 WeakPolarHBondContact O-CG1 3.37Å; L406-I410 PolarHBondContact O-N 3.17Å; K407-I410 PolarHBondContact O-N 2.73Å; K408-I410 PolarHBondContact O-N 3.09Å; I410-L413 PolarHBondContact O-N 2.95Å; I410-A414 VanDerWaalsContact O-CB 3.26Å; I410-A414 WeakPolarHBondContact O-CB 3.43Å; I410-A414 PolarHBondContact O-N 2.75Å; I410-W433 HydrophobicContact CG2-CZ3 4.49Å; I410-V437 HydrophobicContact CG2-CG2 3.78Å
411F89.3Confident86Confident5 Ų552.5 Ų52.52%0.02228%0.281CS..Hα-helixtrans-63.1-47.1178.9178.9-90.7000111.9V397 V401 K407 K408 F409 L413 A414 M415 V437 F438 F466V397-F411 HydrophobicContact CG1-CE2 3.85Å; V397-F411 HydrophobicContact CG1-CZ 4Å; V401-F411 HydrophobicContact CB-CG 4.44Å; V401-F411 HydrophobicContact CG1-CB 3.5Å; V401-F411 VanDerWaalsContact CG1-CB 3.5Å; V401-F411 HydrophobicContact CG1-CD1 4.02Å; V401-F411 HydrophobicContact CG1-CD2 4.36Å; V401-F411 HydrophobicContact CG1-CG 3.71Å; V401-F411 HydrophobicContact CG2-CB 4.37Å; V401-F411 HydrophobicContact CG2-CD2 3.83Å; V401-F411 HydrophobicContact CG2-CE2 4.28Å; V401-F411 HydrophobicContact CG2-CG 4.03Å; K407-F411 WeakPolarHBondContact O-CB 3.42Å; K407-F411 PolarHBondContact O-N 3.22Å; K408-F411 PolarHBondContact O-N 2.95Å; F409-F411 VanDerWaalsContact C-N 3.35Å; F409-F411 PolarHBondContact O-N 2.65Å; F411-L413 VanDerWaalsContact C-N 3.34Å; F411-L413 PolarHBondContact O-N 3.09Å; F411-A414 WeakPolarHBondContact O-CB 3.24Å; F411-A414 PolarHBondContact O-N 3.27Å; F411-M415 HydrophobicContact CD1-CG 3.94Å; F411-M415 HydrophobicContact CE1-CG 3.56Å; F411-M415 HydrophobicContact CE1-SD 4.3Å; F411-M415 HydrophobicContact CE2-CG 4.46Å; F411-M415 HydrophobicContact CZ-CG 3.85Å; F411-M415 HydrophobicContact CZ-SD 4.03Å; F411-M415 WeakPolarHBondContact O-CB 3.41Å; F411-M415 VanDerWaalsContact O-CG 3.29Å; F411-M415 WeakPolarHBondContact O-CG 3.16Å; F411-M415 PolarHBondContact O-N 2.86Å; F411-V437 HydrophobicContact CD2-CG1 3.56Å; F411-V437 HydrophobicContact CE2-CG1 4.24Å; F411-V437 HydrophobicContact CG-CG1 4.47Å; F411-F438 HydrophobicContact CE2-CE1 4.11Å; F411-F466 HydrophobicContact CE2-CE2 4.4Å; F411-F466 HydrophobicContact CZ-CD2 4.14Å; F411-F466 AromaticContact CZ-CE2 3.87Å; F411-F466 HydrophobicContact CZ-CE2 3.87Å
412D88.9Confident86.3Confident68 Ų6852.2 Ų52.236%0.36428%0.279SS..Hα-helixtrans-65.8-38.3-179.8-67.8-18.9000111.5K408 F409 M415 R416K408-D412 WeakPolarHBondContact CD-OD2 3.35Å; K408-D412 VanDerWaalsContact CE-OD1 3.3Å; K408-D412 WeakPolarHBondContact CE-OD1 3.28Å; K408-D412 WeakPolarHBondContact CE-OD2 3.26Å; K408-D412 IonicContact NZ-OD1 2.86Å; K408-D412 PolarHBondContact NZ-OD1 2.97Å; K408-D412 IonicContact NZ-OD2 2.67Å; K408-D412 PolarHBondContact NZ-OD2 2.7Å; K408-D412 WeakPolarHBondContact O-CB 3.24Å; K408-D412 VanDerWaalsContact O-CG 3.23Å; K408-D412 PolarHBondContact O-N 2.97Å; F409-D412 PolarHBondContact O-N 3.21Å; D412-M415 PolarHBondContact O-N 3.4Å; D412-R416 WeakPolarHBondContact O-CB 3.23Å; D412-R416 PolarHBondContact O-N 3.17Å
413L88.9Confident86.8Confident33 Ų3354.8 Ų54.817%0.17328%0.282CS..Hα-helixtrans-66.4-40.4173.6-17657000111.8T23 A27 F409 I410 F411 R416 C417 W433T23-L413 HydrophobicContact CG2-CD2 3.77Å; A27-L413 HydrophobicContact CB-CD1 4.19Å; A27-L413 HydrophobicContact CB-CD2 4.12Å; A27-L413 HydrophobicContact CB-CG 4.29Å; F409-L413 HydrophobicContact CE1-CD2 4.28Å; F409-L413 HydrophobicContact CZ-CD2 4.39Å; F409-L413 WeakPolarHBondContact O-CB 3.17Å; F409-L413 PolarHBondContact O-N 3.03Å; I410-L413 PolarHBondContact O-N 2.95Å; F411-L413 VanDerWaalsContact C-N 3.34Å; F411-L413 PolarHBondContact O-N 3.09Å; L413-R416 PolarHBondContact O-N 2.96Å; L413-C417 WeakPolarHBondContact O-CB 3.49Å; L413-C417 PolarHBondContact O-N 3.26Å; L413-C417 PolarHBondContact O-SG 3.15Å; L413-W433 HydrophobicContact CD2-CH2 3.97Å; L413-W433 HydrophobicContact CG-CH2 3.88Å; L413-W433 HydrophobicContact CG-CZ2 4.33Å
414A88.5Confident87.3Confident0 Ų056.7 Ų56.70%027%0.27CS..Hα-helixtrans-63.2-44.1174.600000111.8I410 F411 C417 K418 W433 V437 F438I410-A414 VanDerWaalsContact O-CB 3.26Å; I410-A414 WeakPolarHBondContact O-CB 3.43Å; I410-A414 PolarHBondContact O-N 2.75Å; F411-A414 WeakPolarHBondContact O-CB 3.24Å; F411-A414 PolarHBondContact O-N 3.27Å; A414-C417 PolarHBondContact O-N 3.2Å; A414-K418 PolarHBondContact O-N 3.31Å; A414-W433 HydrophobicContact CB-CB 4.06Å; A414-W433 HydrophobicContact CB-CD2 3.83Å; A414-W433 HydrophobicContact CB-CE3 3.51Å; A414-W433 HydrophobicContact CB-CG 4.08Å; A414-W433 HydrophobicContact CB-CZ3 4.21Å; A414-V437 HydrophobicContact CB-CB 4.35Å; A414-V437 HydrophobicContact CB-CG2 3.92Å; A414-F438 HydrophobicContact CB-CE2 3.81Å; A414-F438 HydrophobicContact CB-CZ 3.89Å
415M91.2Very high87.6Confident33 Ų3353.6 Ų53.616%0.16325%0.254CS..Hα-helixtrans-57.7-46.7173.9-77.2-61-66.300111.2F411 D412 G419 F438 F466 I469F411-M415 HydrophobicContact CD1-CG 3.94Å; F411-M415 HydrophobicContact CE1-CG 3.56Å; F411-M415 HydrophobicContact CE1-SD 4.3Å; F411-M415 HydrophobicContact CE2-CG 4.46Å; F411-M415 HydrophobicContact CZ-CG 3.85Å; F411-M415 HydrophobicContact CZ-SD 4.03Å; F411-M415 WeakPolarHBondContact O-CB 3.41Å; F411-M415 VanDerWaalsContact O-CG 3.29Å; F411-M415 WeakPolarHBondContact O-CG 3.16Å; F411-M415 PolarHBondContact O-N 2.86Å; D412-M415 PolarHBondContact O-N 3.4Å; M415-G419 WeakPolarHBondContact O-CA 3.24Å; M415-G419 PolarHBondContact O-N 3.08Å; M415-F438 HydrophobicContact CG-CZ 4.32Å; M415-F438 HydrophobicContact SD-CE1 3.81Å; M415-F438 HydrophobicContact SD-CZ 3.83Å; M415-F466 HydrophobicContact CE-CB 4.09Å; M415-F466 HydrophobicContact CE-CD2 4.1Å; M415-F466 HydrophobicContact SD-CD2 4.17Å; M415-I469 HydrophobicContact CE-CB 4.23Å; M415-I469 HydrophobicContact CE-CD1 3.59Å; M415-I469 HydrophobicContact CE-CG2 4.28Å; M415-I469 WeakPolarHBondContact O-CD1 3.35Å; M415-I469 HydrophobicContact SD-CB 4.09Å; M415-I469 HydrophobicContact SD-CD1 4.25Å; M415-I469 HydrophobicContact SD-CG2 3.54Å; M415-I469 VanDerWaalsContact SD-CG2 3.54Å
416R89.2Confident87.7Confident183 Ų18348.5 Ų48.569%0.69122%0.223SC*.Hα-helixtrans-63.1-47.6177.3-173.7176-179.5158.90.7112.2D412 L413 G419 E420D412-R416 WeakPolarHBondContact O-CB 3.23Å; D412-R416 PolarHBondContact O-N 3.17Å; L413-R416 PolarHBondContact O-N 2.96Å; R416-G419 PolarHBondContact O-N 3.06Å; R416-E420 PolarHBondContact O-N 2.75Å
417C88.3Confident87.8Confident0 Ų048.5 Ų48.50%022%0.222CC..Hα-helixtrans-61.8-48.4-179.3-69.70000112.2Y30 F31 L413 A414 G419 E420 W433Y30-C417 HydrophobicContact CD1-CB 3.94Å; Y30-C417 HydrophobicContact CE1-CB 3.8Å; Y30-C417 WeakPolarHBondContact CE1-O 3.44Å; F31-C417 VanDerWaalsContact CE2-SG 3.53Å; F31-C417 HydrophobicContact CZ-CB 4.3Å; L413-C417 WeakPolarHBondContact O-CB 3.49Å; L413-C417 PolarHBondContact O-N 3.26Å; L413-C417 PolarHBondContact O-SG 3.15Å; A414-C417 PolarHBondContact O-N 3.2Å; C417-G419 VanDerWaalsContact C-N 3.34Å; C417-E420 PolarHBondContact O-N 3.49Å; C417-W433 HydrophobicContact CB-CZ2 4.25Å; C417-W433 VanDerWaalsContact SG-CZ2 3.56Å
418K88.7Confident87.8Confident7 Ų744 Ų443%0.0320%0.202CC..Hα-helixtrans-73-27.6178.2-70.3-161.776.3-1780112.6A414 E420 D421 V422 R428 W433 D434 F438 I469A414-K418 PolarHBondContact O-N 3.31Å; K418-E420 VanDerWaalsContact C-N 3.27Å; K418-E420 PolarHBondContact O-N 2.91Å; K418-D421 WeakPolarHBondContact O-CB 3.27Å; K418-D421 PolarHBondContact O-N 3.18Å; K418-D421 VanDerWaalsContact O-N 3.09Å; K418-V422 WeakPolarHBondContact O-CG2 3.24Å; K418-V422 PolarHBondContact O-N 3.32Å; K418-R428 PolarHBondContact NZ-O 2.72Å; K418-R428 VanDerWaalsContact NZ-O 3.11Å; K418-W433 HydrophobicContact CD-CB 4.23Å; K418-W433 HydrophobicContact CG-CB 4.27Å; K418-D434 IonicContact NZ-OD1 2.71Å; K418-D434 PolarHBondContact NZ-OD1 3.03Å; K418-D434 IonicContact NZ-OD2 3.91Å; K418-F438 HydrophobicContact CD-CD2 3.56Å; K418-F438 HydrophobicContact CD-CE2 3.37Å; K418-F438 HydrophobicContact CD-CZ 4.41Å; K418-F438 HydrophobicContact CG-CE2 4.06Å; K418-I469 HydrophobicContact CB-CB 4.37Å; K418-I469 HydrophobicContact CB-CG1 4.25Å; K418-I469 HydrophobicContact CB-CG2 3.53Å; K418-I469 HydrophobicContact CD-CG2 4.12Å; K418-I469 HydrophobicContact CG-CG2 4.35Å; K418-I469 PolarHBondContact NZ-O 3.45Å
419G90.1Very high87.7Confident15 Ų1545.2 Ų45.216%0.15521%0.207CC..Hα-helixtrans-59.9-36.8172.300000112.7M415 R416 C417 D421 V422 K423M415-G419 WeakPolarHBondContact O-CA 3.24Å; M415-G419 PolarHBondContact O-N 3.08Å; R416-G419 PolarHBondContact O-N 3.06Å; C417-G419 VanDerWaalsContact C-N 3.34Å; G419-D421 VanDerWaalsContact C-N 3.3Å; G419-D421 PolarHBondContact O-N 3.16Å; G419-V422 PolarHBondContact O-N 3.26Å; G419-K423 WeakPolarHBondContact O-CG 3.37Å; G419-K423 PolarHBondContact O-N 3.49Å
420E88.4Confident87.5Confident59 Ų5946.9 Ų46.928%0.27622%0.22SC..Hα-helixtrans-68.2-26.9173.9-66.5-58.2130.200113.5F31 R416 C417 K418 K423 K424F31-E420 HydrophobicContact CE1-CB 4.19Å; F31-E420 HydrophobicContact CE1-CG 4.11Å; F31-E420 HydrophobicContact CZ-CG 4.38Å; R416-E420 PolarHBondContact O-N 2.75Å; C417-E420 PolarHBondContact O-N 3.49Å; K418-E420 VanDerWaalsContact C-N 3.27Å; K418-E420 PolarHBondContact O-N 2.91Å; E420-K423 IonicContact OE1-NZ 3.79Å; E420-K423 PolarHBondContact OE1-NZ 3.15Å; E420-K424 WeakPolarHBondContact O-CD 3.15Å; E420-K424 WeakPolarHBondContact O-CG 3.26Å
421D87.9Confident87.2Confident5 Ų545.9 Ų45.93%0.02722%0.216CC..Hα-helixtrans-73.7-42.3171.3-74.63.9000111Y30 K418 G419 K423 K424 A425 I426 R428Y30-D421 VanDerWaalsContact OH-CG 3.26Å; Y30-D421 PolarHBondContact OH-OD2 3.13Å; K418-D421 WeakPolarHBondContact O-CB 3.27Å; K418-D421 PolarHBondContact O-N 3.18Å; K418-D421 VanDerWaalsContact O-N 3.09Å; G419-D421 VanDerWaalsContact C-N 3.3Å; G419-D421 PolarHBondContact O-N 3.16Å; D421-K423 VanDerWaalsContact C-N 3.32Å; D421-K423 PolarHBondContact O-N 3.08Å; D421-K424 CarbonylContact O-C 3.48Å; D421-K424 WeakPolarHBondContact O-CA 3.24Å; D421-K424 WeakPolarHBondContact O-CB 3.4Å; D421-K424 PolarHBondContact O-N 3.2Å; D421-A425 PolarHBondContact O-N 2.73Å; D421-I426 CarbonylContact C-O 3.32Å; D421-I426 HydrophobicContact CB-CB 4.12Å; D421-I426 HydrophobicContact CB-CG2 4.22Å; D421-I426 WeakPolarHBondContact O-CB 3.41Å; D421-I426 PolarHBondContact O-N 3.28Å; D421-R428 IonicContact OD1-NH2 2.75Å; D421-R428 PolarHBondContact OD1-NH2 3.13Å; D421-R428 IonicContact OD2-CZ 2.63Å; D421-R428 IonicContact OD2-NE 3.18Å; D421-R428 PolarHBondContact OD2-NE 2.85Å; D421-R428 IonicContact OD2-NH2 2.88Å; D421-R428 PolarHBondContact OD2-NH2 3.23Å
422V89.1Confident86.8Confident13 Ų1349.1 Ų49.18%0.07923%0.233CC..Hα-helixtrans-59.1-43.2177.2172.90000110.9K418 G419 K424 A425 L427 R468 I469 D496K418-V422 WeakPolarHBondContact O-CG2 3.24Å; K418-V422 PolarHBondContact O-N 3.32Å; G419-V422 PolarHBondContact O-N 3.26Å; V422-K424 PolarHBondContact O-N 2.87Å; V422-K424 VanDerWaalsContact O-N 3.14Å; V422-A425 WeakPolarHBondContact O-CA 3.26Å; V422-A425 PolarHBondContact O-N 3.36Å; V422-L427 HydrophobicContact CG2-CD2 4.09Å; V422-R468 HydrophobicContact CG1-CB 4.23Å; V422-R468 HydrophobicContact CG2-CB 4.22Å; V422-I469 HydrophobicContact CG2-CG1 3.89Å; V422-D496 HydrophobicContact CG1-CB 3.99Å
423K87.6Confident86.7Confident121 Ų12145.9 Ų45.953%0.52622%0.215SC..THydrogen-bonded Turntrans-58.1-24.5173.1-71.6175.3-178.7174.90114.2G419 E420 D421 A425 D496G419-K423 WeakPolarHBondContact O-CG 3.37Å; G419-K423 PolarHBondContact O-N 3.49Å; E420-K423 IonicContact OE1-NZ 3.79Å; E420-K423 PolarHBondContact OE1-NZ 3.15Å; D421-K423 VanDerWaalsContact C-N 3.32Å; D421-K423 PolarHBondContact O-N 3.08Å; K423-A425 VanDerWaalsContact C-N 3.31Å; K423-D496 WeakPolarHBondContact CG-OD2 3.44Å
424K86.6Confident86.4Confident110 Ų11044.4 Ų44.448%0.47821%0.208SC..THydrogen-bonded Turntrans-94.110.3176.6-65170.9-172.4172.70112E420 D421 V422 I426E420-K424 WeakPolarHBondContact O-CD 3.15Å; E420-K424 WeakPolarHBondContact O-CG 3.26Å; D421-K424 CarbonylContact O-C 3.48Å; D421-K424 WeakPolarHBondContact O-CA 3.24Å; D421-K424 WeakPolarHBondContact O-CB 3.4Å; D421-K424 PolarHBondContact O-N 3.2Å; V422-K424 PolarHBondContact O-N 2.87Å; V422-K424 VanDerWaalsContact O-N 3.14Å; K424-I426 HydrophobicContact CB-CD1 3.98Å; K424-I426 HydrophobicContact CB-CG1 4.19Å; K424-I426 PolarHBondContact O-N 2.92Å
425A87.5Confident86Confident5 Ų550 Ų504%0.04124%0.237CC..THydrogen-bonded Turntrans54.436.4-171.500000112.8K40 I41 D421 V422 K423 G494K40-A425 WeakPolarHBondContact CA-O 3.4Å; K40-A425 HydrophobicContact CG-CB 4.02Å; I41-A425 HydrophobicContact CB-CB 4.42Å; I41-A425 WeakPolarHBondContact CG1-O 3.21Å; I41-A425 PolarHBondContact N-O 2.78Å; D421-A425 PolarHBondContact O-N 2.73Å; V422-A425 WeakPolarHBondContact O-CA 3.26Å; V422-A425 PolarHBondContact O-N 3.36Å; K423-A425 VanDerWaalsContact C-N 3.31Å; A425-G494 WeakPolarHBondContact CB-O 3.09Å
426I85.8Confident85.5Confident22 Ų2253 Ų5311%0.11325%0.253CS..BIsolated β-bridgetrans-107117.9177.7-66.6170.6000109.1D421 K424D421-I426 CarbonylContact C-O 3.32Å; D421-I426 HydrophobicContact CB-CB 4.12Å; D421-I426 HydrophobicContact CB-CG2 4.22Å; D421-I426 WeakPolarHBondContact O-CB 3.41Å; D421-I426 PolarHBondContact O-N 3.28Å; K424-I426 HydrophobicContact CB-CD1 3.98Å; K424-I426 HydrophobicContact CB-CG1 4.19Å; K424-I426 PolarHBondContact O-N 2.92Å
427L85.1Confident85.3Confident39 Ų3945.4 Ų45.420%0.20423%0.227CC..  trans-111.2124.2170.2-62.7-178.4000109.8I41 V422 C473 V474I41-L427 HydrophobicContact CD1-CB 4.49Å; I41-L427 HydrophobicContact CD1-CD1 3.61Å; I41-L427 HydrophobicContact CD1-CG 3.75Å; V422-L427 HydrophobicContact CG2-CD2 4.09Å; L427-C473 WeakPolarHBondContact CD1-O 3.42Å; L427-V474 HydrophobicContact CD1-CG2 3.96Å
428R83.3Confident85.3Confident34 Ų3445.4 Ų45.413%0.12823%0.227CC..  trans-144.4145.417762.1177.3169175.8-9.2112.2Y30 K418 D421 N430 A472Y30-R428 PolarHBondContact OH-NH2 3.21Å; Y30-R428 VanDerWaalsContact OH-NH2 3.16Å; K418-R428 PolarHBondContact NZ-O 2.72Å; K418-R428 VanDerWaalsContact NZ-O 3.11Å; D421-R428 IonicContact OD1-NH2 2.75Å; D421-R428 PolarHBondContact OD1-NH2 3.13Å; D421-R428 IonicContact OD2-CZ 2.63Å; D421-R428 IonicContact OD2-NE 3.18Å; D421-R428 PolarHBondContact OD2-NE 2.85Å; D421-R428 IonicContact OD2-NH2 2.88Å; D421-R428 PolarHBondContact OD2-NH2 3.23Å; R428-N430 WeakPolarHBondContact CB-OD1 3.19Å; R428-N430 WeakPolarHBondContact CD-OD1 3.47Å; R428-A472 VanDerWaalsContact O-CB 3.32Å; R428-A472 WeakPolarHBondContact O-CB 3.3Å
429K83.6Confident85.3Confident81 Ų8150 Ų5035%0.35225%0.247SC..SBendtrans-106.71.3178.1-70.4178.8-178-179.10113.3D434 L449 F471 A472K429-D434 VanDerWaalsContact C-CG 3.41Å; K429-D434 WeakPolarHBondContact CA-OD2 3.39Å; K429-D434 WeakPolarHBondContact O-CB 3.38Å; K429-L449 PolarHBondContact NZ-O 3.29Å; K429-F471 VanDerWaalsContact CE-O 3.29Å; K429-F471 WeakPolarHBondContact CE-O 3.22Å; K429-A472 HydrophobicContact CG-CB 3.59Å
430N81.6Confident85.1Confident121 Ų12154.8 Ų54.865%0.64727%0.269SS*.  trans-106.615-171.867-11.8000113.7R428 D434R428-N430 WeakPolarHBondContact CB-OD1 3.19Å; R428-N430 WeakPolarHBondContact CD-OD1 3.47Å; N430-D434 PolarHBondContact N-OD2 3.46Å
431S81.3Confident85Confident10 Ų1053.1 Ų53.17%0.0726%0.263CS..SBendtrans-78.5163.6177.171.50000112.6W433 D434 L435S431-W433 PolarHBondContact O-N 3.45Å; S431-W433 PolarHBondContact OG-N 3.19Å; S431-D434 WeakPolarHBondContact CB-OD2 3.15Å; S431-D434 PolarHBondContact N-OD2 3.01Å; S431-D434 WeakPolarHBondContact O-CB 3.42Å; S431-D434 PolarHBondContact O-N 3.03Å; S431-D434 VanDerWaalsContact O-N 3.14Å; S431-D434 VanDerWaalsContact OG-CG 3.3Å; S431-D434 PolarHBondContact OG-N 3.01Å; S431-D434 VanDerWaalsContact OG-N 3.12Å; S431-D434 PolarHBondContact OG-OD2 2.82Å; S431-L435 PolarHBondContact O-N 3.37Å
432I81Confident85.1Confident72 Ų7253.3 Ų53.337%0.36926%0.263SS..Hα-helixtrans-59.4-32.9170.3-162.7173.3000111.9A26 D434 L435 L436A26-I432 HydrophobicContact CB-CD1 3.79Å; A26-I432 HydrophobicContact CB-CG2 4.27Å; I432-D434 VanDerWaalsContact C-N 3.32Å; I432-D434 PolarHBondContact O-N 3.39Å; I432-L435 PolarHBondContact O-N 3.16Å; I432-L436 HydrophobicContact CD1-CD1 4.26Å; I432-L436 HydrophobicContact CG1-CD1 3.86Å; I432-L436 HydrophobicContact CG1-CG 4.24Å; I432-L436 WeakPolarHBondContact O-CB 3.29Å; I432-L436 VanDerWaalsContact O-CG 3.32Å; I432-L436 WeakPolarHBondContact O-CG 3.49Å; I432-L436 PolarHBondContact O-N 3.48Å
433W86.2Confident85.2Confident0 Ų054.9 Ų54.90%028%0.277CS..Hα-helixtrans-68-32.8177.3-54.7119.6000112.7T23 A27 Y30 I410 L413 A414 C417 K418 S431 L435 V437 F438T23-W433 HydrophobicContact CG2-CH2 3.73Å; T23-W433 HydrophobicContact CG2-CZ3 3.71Å; A27-W433 HydrophobicContact CB-CH2 4.22Å; A27-W433 HydrophobicContact CB-CZ2 3.79Å; Y30-W433 AromaticContact CD2-CD1 3.74Å; Y30-W433 AromaticContact CD2-NE1 3.56Å; Y30-W433 AromaticContact CE2-CD1 3.53Å; Y30-W433 AromaticContact CE2-NE1 3.78Å; Y30-W433 AromaticContact CG-NE1 3.66Å; Y30-W433 AromaticContact CZ-CD1 3.87Å; I410-W433 HydrophobicContact CG2-CZ3 4.49Å; L413-W433 HydrophobicContact CD2-CH2 3.97Å; L413-W433 HydrophobicContact CG-CH2 3.88Å; L413-W433 HydrophobicContact CG-CZ2 4.33Å; A414-W433 HydrophobicContact CB-CB 4.06Å; A414-W433 HydrophobicContact CB-CD2 3.83Å; A414-W433 HydrophobicContact CB-CE3 3.51Å; A414-W433 HydrophobicContact CB-CG 4.08Å; A414-W433 HydrophobicContact CB-CZ3 4.21Å; C417-W433 HydrophobicContact CB-CZ2 4.25Å; C417-W433 VanDerWaalsContact SG-CZ2 3.56Å; K418-W433 HydrophobicContact CD-CB 4.23Å; K418-W433 HydrophobicContact CG-CB 4.27Å; S431-W433 PolarHBondContact O-N 3.45Å; S431-W433 PolarHBondContact OG-N 3.19Å; W433-L435 VanDerWaalsContact C-N 3.35Å; W433-V437 WeakPolarHBondContact O-CB 3.49Å; W433-V437 PolarHBondContact O-N 3.41Å; W433-F438 HydrophobicContact CB-CD2 4.21Å; W433-F438 HydrophobicContact CB-CE2 4.04Å; W433-F438 PolarHBondContact O-N 3.24Å
434D83.8Confident85.3Confident3 Ų352.8 Ų52.82%0.01627%0.269CS..Iπ-helixtrans-63.1-44.6172.8-69.2-61.3000110.8K418 K429 N430 S431 I432 F438 K439 R442K418-D434 IonicContact NZ-OD1 2.71Å; K418-D434 PolarHBondContact NZ-OD1 3.03Å; K418-D434 IonicContact NZ-OD2 3.91Å; K429-D434 VanDerWaalsContact C-CG 3.41Å; K429-D434 WeakPolarHBondContact CA-OD2 3.39Å; K429-D434 WeakPolarHBondContact O-CB 3.38Å; N430-D434 PolarHBondContact N-OD2 3.46Å; S431-D434 WeakPolarHBondContact CB-OD2 3.15Å; S431-D434 PolarHBondContact N-OD2 3.01Å; S431-D434 WeakPolarHBondContact O-CB 3.42Å; S431-D434 PolarHBondContact O-N 3.03Å; S431-D434 VanDerWaalsContact O-N 3.14Å; S431-D434 VanDerWaalsContact OG-CG 3.3Å; S431-D434 PolarHBondContact OG-N 3.01Å; S431-D434 VanDerWaalsContact OG-N 3.12Å; S431-D434 PolarHBondContact OG-OD2 2.82Å; I432-D434 VanDerWaalsContact C-N 3.32Å; I432-D434 PolarHBondContact O-N 3.39Å; D434-F438 PolarHBondContact O-N 3.25Å; D434-K439 WeakPolarHBondContact O-CA 3.29Å; D434-K439 WeakPolarHBondContact O-CB 3.31Å; D434-K439 PolarHBondContact O-N 3.33Å; D434-R442 IonicContact OD1-CZ 3.37Å; D434-R442 IonicContact OD1-NH1 3.47Å; D434-R442 PolarHBondContact OD1-NH1 3.49Å; D434-R442 IonicContact OD1-NH2 3.87Å; D434-R442 PolarHBondContact OD1-NH2 3.35Å
435L79.7Confident85.5Confident118 Ų11848.6 Ų48.662%0.61825%0.251SS*.Iπ-helixtrans-67.1-41.9178.6-176.663.9000112.6S431 I432 W433S431-L435 PolarHBondContact O-N 3.37Å; I432-L435 PolarHBondContact O-N 3.16Å; W433-L435 VanDerWaalsContact C-N 3.35Å
436L80.4Confident85.8Confident96 Ų9648.8 Ų48.850%0.50325%0.254SS..Iπ-helixtrans-82.8-34.5-173.1-67.5176.6000114I432I432-L436 HydrophobicContact CD1-CD1 4.26Å; I432-L436 HydrophobicContact CG1-CD1 3.86Å; I432-L436 HydrophobicContact CG1-CG 4.24Å; I432-L436 WeakPolarHBondContact O-CB 3.29Å; I432-L436 VanDerWaalsContact O-CG 3.32Å; I432-L436 WeakPolarHBondContact O-CG 3.49Å; I432-L436 PolarHBondContact O-N 3.48Å
437V85.4Confident86.1Confident22 Ų2251 Ų5113%0.13327%0.266CS..Iπ-helixtrans-123.6-61.4-167.8-176.50000111.4I410 F411 A414 W433I410-V437 HydrophobicContact CG2-CG2 3.78Å; F411-V437 HydrophobicContact CD2-CG1 3.56Å; F411-V437 HydrophobicContact CE2-CG1 4.24Å; F411-V437 HydrophobicContact CG-CG1 4.47Å; A414-V437 HydrophobicContact CB-CB 4.35Å; A414-V437 HydrophobicContact CB-CG2 3.92Å; W433-V437 WeakPolarHBondContact O-CB 3.49Å; W433-V437 PolarHBondContact O-N 3.41Å
438F88.6Confident86.5Confident0 Ų052.5 Ų52.50%027%0.274CS..Iπ-helixtrans-83.1-22.1-161.7-59.2-63000114.6F411 A414 M415 K418 W433 D434 N440 V441 R442 I469 C470F411-F438 HydrophobicContact CE2-CE1 4.11Å; A414-F438 HydrophobicContact CB-CE2 3.81Å; A414-F438 HydrophobicContact CB-CZ 3.89Å; M415-F438 HydrophobicContact CG-CZ 4.32Å; M415-F438 HydrophobicContact SD-CE1 3.81Å; M415-F438 HydrophobicContact SD-CZ 3.83Å; K418-F438 HydrophobicContact CD-CD2 3.56Å; K418-F438 HydrophobicContact CD-CE2 3.37Å; K418-F438 HydrophobicContact CD-CZ 4.41Å; K418-F438 HydrophobicContact CG-CE2 4.06Å; W433-F438 HydrophobicContact CB-CD2 4.21Å; W433-F438 HydrophobicContact CB-CE2 4.04Å; W433-F438 PolarHBondContact O-N 3.24Å; D434-F438 PolarHBondContact O-N 3.25Å; F438-N440 VanDerWaalsContact C-N 3.29Å; F438-N440 PolarHBondContact O-N 3.41Å; F438-V441 PolarHBondContact O-N 2.92Å; F438-V441 VanDerWaalsContact O-N 3.12Å; F438-R442 PolarHBondContact O-N 3.02Å; F438-I469 HydrophobicContact CE1-CG2 3.99Å; F438-I469 HydrophobicContact CE2-CG2 3.92Å; F438-I469 HydrophobicContact CZ-CG2 3.49Å; F438-I469 VanDerWaalsContact CZ-CG2 3.49Å; F438-C470 HydrophobicContact CD1-CB 4.01Å; F438-C470 HydrophobicContact CE1-CB 4.34Å
439K87.7Confident87.1Confident103 Ų10351.1 Ų51.145%0.44827%0.269SS..Hα-helixtrans-55.3-42.9178.2179.1177.8-177-178.40112.4D434 V441 R442 A443D434-K439 WeakPolarHBondContact O-CA 3.29Å; D434-K439 WeakPolarHBondContact O-CB 3.31Å; D434-K439 PolarHBondContact O-N 3.33Å; K439-V441 VanDerWaalsContact C-N 3.35Å; K439-R442 PolarHBondContact O-N 2.76Å; K439-A443 VanDerWaalsContact O-CB 3.29Å; K439-A443 WeakPolarHBondContact O-CB 3.43Å; K439-A443 PolarHBondContact O-N 3.02Å
440N85.9Confident87.6Confident117 Ų11748.8 Ų48.863%0.62626%0.263SS*.Hα-helixtrans-67.1-38.6180-68.3-22.1000111.7F438F438-N440 VanDerWaalsContact C-N 3.29Å; F438-N440 PolarHBondContact O-N 3.41Å
441V86.7Confident88.2Confident24 Ų2443.1 Ų43.115%0.14523%0.233CC..Hα-helixtrans-67.8-46.1177.2-1730000110V397 F438 K439 A443 E444 F445 C470V397-V441 HydrophobicContact CG1-CG2 4.48Å; V397-V441 HydrophobicContact CG2-CG1 4.02Å; F438-V441 PolarHBondContact O-N 2.92Å; F438-V441 VanDerWaalsContact O-N 3.12Å; K439-V441 VanDerWaalsContact C-N 3.35Å; V441-A443 VanDerWaalsContact C-N 3.33Å; V441-A443 PolarHBondContact O-N 2.92Å; V441-E444 WeakPolarHBondContact O-CB 3.33Å; V441-E444 PolarHBondContact O-N 2.7Å; V441-E444 VanDerWaalsContact O-N 3.12Å; V441-F445 HydrophobicContact CG1-CE2 4.49Å; V441-F445 VanDerWaalsContact O-CD2 3.31Å; V441-F445 WeakPolarHBondContact O-CD2 3.43Å; V441-C470 VanDerWaalsContact CB-SG 3.54Å; V441-C470 WeakPolarHBondContact CG1-SG 3.49Å
442R90.8Very high88.9Confident9 Ų942.7 Ų42.73%0.03423%0.23CC..Hα-helixtrans-64.4-35.1178-69.1-166-61.9-91.71.3113.7D434 F438 K439 E444 F445 G446 D447 C470 F471D434-R442 IonicContact OD1-CZ 3.37Å; D434-R442 IonicContact OD1-NH1 3.47Å; D434-R442 PolarHBondContact OD1-NH1 3.49Å; D434-R442 IonicContact OD1-NH2 3.87Å; D434-R442 PolarHBondContact OD1-NH2 3.35Å; F438-R442 PolarHBondContact O-N 3.02Å; K439-R442 PolarHBondContact O-N 2.76Å; R442-E444 PolarHBondContact O-N 2.92Å; R442-F445 CarbonylContact O-C 3.46Å; R442-F445 WeakPolarHBondContact O-CA 3.46Å; R442-F445 PolarHBondContact O-N 2.96Å; R442-G446 PolarHBondContact O-N 2.88Å; R442-D447 HydrophobicContact CB-CB 4.28Å; R442-D447 WeakPolarHBondContact CB-OD1 3.28Å; R442-D447 WeakPolarHBondContact CD-OD1 3.46Å; R442-D447 IonicContact NE-OD1 3.84Å; R442-D447 PolarHBondContact NE-OD1 3.06Å; R442-D447 WeakPolarHBondContact O-CA 3.41Å; R442-D447 PolarHBondContact O-N 3.15Å; R442-C470 WeakPolarHBondContact CD-O 3.35Å; R442-C470 VanDerWaalsContact CG-O 3.23Å; R442-C470 WeakPolarHBondContact CG-O 3.5Å; R442-C470 PolarHBondContact NH1-O 2.88Å; R442-F471 WeakPolarHBondContact CD-O 3.37Å; R442-F471 HydrophobicContact CG-CD1 4.02Å
443A90.8Very high89.6Confident45 Ų4539.8 Ų39.837%0.37222%0.215SC..Hα-helixtrans-58.1-30.3175.100000112K376 K439 V441 F445 G446K376-A443 WeakPolarHBondContact CG-O 3.45Å; K439-A443 VanDerWaalsContact O-CB 3.29Å; K439-A443 WeakPolarHBondContact O-CB 3.43Å; K439-A443 PolarHBondContact O-N 3.02Å; V441-A443 VanDerWaalsContact C-N 3.33Å; V441-A443 PolarHBondContact O-N 2.92Å; A443-F445 PolarHBondContact O-N 3.4Å; A443-G446 PolarHBondContact O-N 3.48Å
444E89.1Confident89.9Confident77 Ų7739.8 Ų39.836%0.3622%0.215SC..THydrogen-bonded Turntrans-66.7-18.3174.8-65.7-64.6119.600113.9K376 V441 R442K376-E444 VanDerWaalsContact CE-CA 3.48Å; K376-E444 VanDerWaalsContact CE-OE1 3.3Å; K376-E444 WeakPolarHBondContact CE-OE1 3.46Å; K376-E444 WeakPolarHBondContact CE-OE2 3.26Å; K376-E444 IonicContact NZ-OE1 3.54Å; K376-E444 PolarHBondContact NZ-OE1 3.34Å; K376-E444 IonicContact NZ-OE2 3Å; K376-E444 PolarHBondContact NZ-OE2 3.39Å; V441-E444 WeakPolarHBondContact O-CB 3.33Å; V441-E444 PolarHBondContact O-N 2.7Å; V441-E444 VanDerWaalsContact O-N 3.12Å; R442-E444 PolarHBondContact O-N 2.92Å
445F92.2Very high90.1Very high22 Ų2239.9 Ų39.910%0.09622%0.217CC..THydrogen-bonded Turntrans-117.318.5-179.5-60.2-97.1000111.9M375 V393 V441 R442 A443 L449 F471M375-F445 HydrophobicContact CE-CB 4.08Å; M375-F445 HydrophobicContact CE-CD1 3.87Å; M375-F445 HydrophobicContact CE-CG 4.48Å; M375-F445 HydrophobicContact SD-CD1 3.71Å; M375-F445 HydrophobicContact SD-CE1 4.46Å; V393-F445 HydrophobicContact CB-CZ 4.39Å; V393-F445 HydrophobicContact CG1-CE2 4.17Å; V393-F445 HydrophobicContact CG1-CZ 3.63Å; V393-F445 HydrophobicContact CG2-CE1 4.12Å; V393-F445 HydrophobicContact CG2-CZ 3.77Å; V441-F445 HydrophobicContact CG1-CE2 4.49Å; V441-F445 VanDerWaalsContact O-CD2 3.31Å; V441-F445 WeakPolarHBondContact O-CD2 3.43Å; R442-F445 CarbonylContact O-C 3.46Å; R442-F445 WeakPolarHBondContact O-CA 3.46Å; R442-F445 PolarHBondContact O-N 2.96Å; A443-F445 PolarHBondContact O-N 3.4Å; F445-L449 HydrophobicContact CB-CD1 4.12Å; F445-F471 HydrophobicContact CB-CE1 3.82Å; F445-F471 HydrophobicContact CD1-CE1 4.34Å; F445-F471 HydrophobicContact CD1-CZ 4.29Å; F445-F471 AromaticContact CD2-CE1 3.39Å; F445-F471 HydrophobicContact CD2-CE1 3.39Å; F445-F471 AromaticContact CD2-CZ 3.56Å; F445-F471 HydrophobicContact CD2-CZ 3.56Å; F445-F471 HydrophobicContact CE1-CZ 4.4Å; F445-F471 HydrophobicContact CE2-CE1 4.02Å; F445-F471 AromaticContact CE2-CZ 3.68Å; F445-F471 HydrophobicContact CE2-CZ 3.68Å; F445-F471 AromaticContact CG-CE1 3.59Å; F445-F471 HydrophobicContact CG-CE1 3.59Å; F445-F471 AromaticContact CG-CZ 3.89Å; F445-F471 HydrophobicContact CG-CZ 3.89Å; F445-F471 HydrophobicContact CZ-CZ 4.11Å
446G91.9Very high89.9Confident10 Ų1038 Ų3810%0.10321%0.214CC..THydrogen-bonded Turntrans84.8-0.9176.600000116.3R442 A443 N448R442-G446 PolarHBondContact O-N 2.88Å; A443-G446 PolarHBondContact O-N 3.48Å; G446-N448 PolarHBondContact O-N 3.4Å
447D92.1Very high89.6Confident68 Ų6835.8 Ų35.836%0.36421%0.209SC..SBendtrans56.314.4175.8-158.128.5000116.1R442R442-D447 HydrophobicContact CB-CB 4.28Å; R442-D447 WeakPolarHBondContact CB-OD1 3.28Å; R442-D447 WeakPolarHBondContact CD-OD1 3.46Å; R442-D447 IonicContact NE-OD1 3.84Å; R442-D447 PolarHBondContact NE-OD1 3.06Å; R442-D447 WeakPolarHBondContact O-CA 3.41Å; R442-D447 PolarHBondContact O-N 3.15Å
448N94.8Very high89.1Confident71 Ų7137.4 Ų37.438%0.3822%0.22SC..  trans-112.4-1.6-175-161.237.5000114.6K379 P380 T381 G446 S450K379-N448 HydrophobicContact CB-CB 4.03Å; K379-N448 WeakPolarHBondContact O-CB 3.32Å; K379-N448 PolarHBondContact O-ND2 3.29Å; P380-N448 CarbonylContact O-C 3.54Å; T381-N448 WeakPolarHBondContact CA-O 3.5Å; T381-N448 VanDerWaalsContact CG2-ND2 3.3Å; T381-N448 WeakPolarHBondContact CG2-ND2 3.39Å; G446-N448 PolarHBondContact O-N 3.4Å; N448-S450 PolarHBondContact O-N 3.06Å
449L95.6Very high88.5Confident4 Ų437.9 Ų37.92%0.02122%0.223CC..  trans-60.2133.8-179.6-66.4173.8000112.1M375 P380 F383 K429 F445 I452 F471M375-L449 HydrophobicContact CE-CD1 4.08Å; M375-L449 HydrophobicContact CE-CD2 4.19Å; P380-L449 HydrophobicContact CB-CD2 4.35Å; P380-L449 HydrophobicContact CG-CD2 3.99Å; P380-L449 WeakPolarHBondContact O-CD2 3.34Å; P380-L449 PolarHBondContact O-N 2.96Å; F383-L449 HydrophobicContact CB-CD2 3.6Å; F383-L449 HydrophobicContact CD1-CD1 4.31Å; K429-L449 PolarHBondContact NZ-O 3.29Å; F445-L449 HydrophobicContact CB-CD1 4.12Å; L449-I452 HydrophobicContact CD1-CD1 4.14Å; L449-I452 HydrophobicContact CD1-CG1 4.5Å; L449-F471 HydrophobicContact CD1-CD1 3.88Å; L449-F471 HydrophobicContact CD1-CE1 4.17Å; L449-F471 HydrophobicContact CD1-CG 4.44Å
450S93.3Very high88Confident32 Ų3234 Ų3422%0.22421%0.208CC..  trans-121.5-29.4174.257.20000112.1T381 N448 C473 V474T381-S450 PolarHBondContact O-N 2.88Å; T381-S450 PolarHBondContact O-OG 2.88Å; N448-S450 PolarHBondContact O-N 3.06Å; S450-C473 WeakPolarHBondContact O-CB 3.35Å; S450-V474 PolarHBondContact O-N 3.47Å
451L95.2Very high87.7Confident3 Ų330.5 Ų30.52%0.01620%0.196CC..EExtended strand (participates in β ladder)trans-139128.3-178.9177.461.1000111.4F325 T381 L382 F383 I453 V474F325-L451 HydrophobicContact CD1-CD1 4.06Å; F325-L451 HydrophobicContact CD1-CD2 4.06Å; F325-L451 HydrophobicContact CD2-CD2 4.27Å; F325-L451 HydrophobicContact CE1-CD1 3.66Å; F325-L451 HydrophobicContact CE1-CD2 3.92Å; F325-L451 HydrophobicContact CE1-CG 4.43Å; F325-L451 HydrophobicContact CE2-CD2 4.14Å; F325-L451 HydrophobicContact CG-CD2 4.24Å; F325-L451 HydrophobicContact CZ-CD1 4.28Å; F325-L451 HydrophobicContact CZ-CD2 3.95Å; T381-L451 PolarHBondContact O-N 3.36Å; T381-L451 VanDerWaalsContact O-N 3.16Å; L382-L451 WeakPolarHBondContact CA-O 3.27Å; L382-L451 HydrophobicContact CD2-CD2 4.3Å; L382-L451 HydrophobicContact CG-CB 4.28Å; L382-L451 HydrophobicContact CG-CD2 4.32Å; F383-L451 PolarHBondContact N-O 2.89Å; L451-I453 HydrophobicContact CD1-CG1 4.07Å; L451-I453 HydrophobicContact CD2-CD1 4.11Å; L451-I453 HydrophobicContact CD2-CG1 4.42Å; L451-I453 HydrophobicContact CG-CD1 4.29Å; L451-I453 HydrophobicContact CG-CG1 4.06Å; L451-V474 HydrophobicContact CD1-CB 3.93Å; L451-V474 HydrophobicContact CD1-CG1 3.71Å
452I96.3Very high87.6Confident0 Ų034.4 Ų34.40%021%0.213CC..EExtended strand (participates in β ladder)trans-121.6130.8172.7-59.1-179.6000107.2F383 V385 L449 F467 F471 C473 V474 V475 C476F383-I452 HydrophobicContact CB-CG1 4.27Å; F383-I452 HydrophobicContact CD1-CD1 4.36Å; F383-I452 HydrophobicContact CD1-CG1 4.4Å; F383-I452 HydrophobicContact CD1-CG2 4.44Å; F383-I452 WeakPolarHBondContact O-CA 3.44Å; V385-I452 HydrophobicContact CB-CG2 4.38Å; V385-I452 HydrophobicContact CG1-CG2 3.54Å; L449-I452 HydrophobicContact CD1-CD1 4.14Å; L449-I452 HydrophobicContact CD1-CG1 4.5Å; I452-F467 HydrophobicContact CD1-CD1 3.8Å; I452-F467 HydrophobicContact CD1-CE1 4.49Å; I452-F471 HydrophobicContact CD1-CB 4.26Å; I452-F471 HydrophobicContact CD1-CD2 3.97Å; I452-F471 HydrophobicContact CD1-CG 4.11Å; I452-C473 WeakPolarHBondContact CD1-SG 3.35Å; I452-C473 VanDerWaalsContact CG1-SG 3.59Å; I452-V474 PolarHBondContact N-O 3.05Å; I452-V475 HydrophobicContact CB-CG1 4.35Å; I452-V475 HydrophobicContact CB-CG2 4.22Å; I452-V475 HydrophobicContact CD1-CG2 4.45Å; I452-V475 HydrophobicContact CG2-CG1 4.27Å; I452-V475 VanDerWaalsContact O-CA 3.3Å; I452-V475 WeakPolarHBondContact O-CA 3.36Å; I452-C476 PolarHBondContact O-N 2.93Å
453I95.3Very high87.4Confident11 Ų1134.1 Ų34.16%0.05621%0.212CC..EExtended strand (participates in β ladder)trans-121.1121178.3-59.1173.2000107.7F325 F346 M350 F383 P384 V385 L451 L490F325-I453 HydrophobicContact CE2-CD1 4.2Å; F325-I453 HydrophobicContact CZ-CD1 3.65Å; F325-I453 HydrophobicContact CZ-CG1 4.29Å; F346-I453 HydrophobicContact CE2-CG2 3.91Å; F346-I453 HydrophobicContact CZ-CB 4.37Å; F346-I453 HydrophobicContact CZ-CG2 3.92Å; M350-I453 HydrophobicContact CE-CD1 3.78Å; M350-I453 HydrophobicContact SD-CD1 3.67Å; F383-I453 PolarHBondContact O-N 2.84Å; P384-I453 CarbonylContact C-O 3.51Å; P384-I453 WeakPolarHBondContact CA-O 3.43Å; V385-I453 PolarHBondContact N-O 2.76Å; L451-I453 HydrophobicContact CD1-CG1 4.07Å; L451-I453 HydrophobicContact CD2-CD1 4.11Å; L451-I453 HydrophobicContact CD2-CG1 4.42Å; L451-I453 HydrophobicContact CG-CD1 4.29Å; L451-I453 HydrophobicContact CG-CG1 4.06Å; I453-L490 HydrophobicContact CG2-CD1 4.28Å
454S92.8Very high87.3Confident0 Ų032 Ų320%020%0.195CC..EExtended strand (participates in β ladder)trans-100.7143.7174.1-1600000111.8V385 M390 V459 C476 E477 G478V385-S454 VanDerWaalsContact O-CA 3.26Å; V385-S454 WeakPolarHBondContact O-CA 3.45Å; V385-S454 PolarHBondContact O-OG 2.9Å; M390-S454 PolarHBondContact SD-OG 3.29Å; M390-S454 VanDerWaalsContact SD-OG 3.37Å; S454-V459 WeakPolarHBondContact OG-CG2 3.3Å; S454-C476 PolarHBondContact N-O 3.07Å; S454-E477 WeakPolarHBondContact O-CA 3.36Å; S454-G478 PolarHBondContact O-N 3.48Å
455G87.5Confident87.3Confident5 Ų530.8 Ų30.85%0.05219%0.191CC..  trans-164.9-166.8175.700000112.5V385 P387 A457V385-G455 PolarHBondContact O-N 3.45Å; P387-G455 VanDerWaalsContact CD-O 3.28Å; P387-G455 WeakPolarHBondContact CD-O 3.42Å; G455-A457 PolarHBondContact O-N 3.45Å; G455-A457 VanDerWaalsContact O-N 3.09Å
456S74.6Confident87.3Confident79 Ų7929.8 Ų29.855%0.55219%0.186SC*.SBendtrans73-30.1-176.8-48.10000116.4
457A76Confident87.4Confident49 Ų4929.3 Ų29.341%0.40518%0.181SC..SBendtrans-156163.7175.200000110.6P387 G455P387-A457 HydrophobicContact CG-CB 3.87Å; P387-A457 WeakPolarHBondContact CG-O 3.32Å; G455-A457 PolarHBondContact O-N 3.45Å; G455-A457 VanDerWaalsContact O-N 3.09Å
458P73.7Confident87.4Confident56 Ų5626.5 Ų26.536%0.36417%0.166SC..  trans-64.9144.1178.2-22.434.6000113.3P387P387-P458 WeakPolarHBondContact CB-O 3.5Å; P387-P458 WeakPolarHBondContact CG-O 3.36Å
459V76.3Confident87.2Confident10 Ų1023.5 Ų23.56%0.06115%0.15CC..  trans-111.7148169.1-167.80000109.8P387 M390 S454 V463 L464 E477P387-V459 HydrophobicContact CB-CG2 3.77Å; P387-V459 HydrophobicContact CG-CG2 3.57Å; M390-V459 HydrophobicContact CE-CG1 4.35Å; M390-V459 HydrophobicContact SD-CG1 4.08Å; M390-V459 HydrophobicContact SD-CG2 3.88Å; S454-V459 WeakPolarHBondContact OG-CG2 3.3Å; V459-V463 HydrophobicContact CG1-CB 3.94Å; V459-V463 HydrophobicContact CG1-CG1 3.85Å; V459-L464 HydrophobicContact CB-CD1 4.25Å; V459-L464 HydrophobicContact CB-CD2 3.96Å; V459-L464 HydrophobicContact CB-CG 3.88Å; V459-L464 HydrophobicContact CG1-CD2 3.95Å; V459-L464 HydrophobicContact CG1-CG 3.74Å; V459-L464 HydrophobicContact CG2-CD2 4.33Å; V459-E477 PolarHBondContact N-OE1 3.03Å
460S76.4Confident87Confident21 Ų2123.3 Ų23.315%0.14715%0.149CC..  trans-76.9153.1174.275.20000113.4E462 V463 L464 H600S460-E462 PolarHBondContact O-N 3.01Å; S460-V463 PolarHBondContact O-N 3.22Å; S460-V463 WeakPolarHBondContact OG-CG2 3.4Å; S460-V463 PolarHBondContact OG-N 3.46Å; S460-L464 WeakPolarHBondContact O-CG 3.44Å; S460-L464 PolarHBondContact O-N 3.31Å; S460-H600 VanDerWaalsContact CB-CE1 3.45Å; S460-H600 WeakPolarHBondContact CB-CE1 3.5Å; S460-H600 WeakPolarHBondContact CB-NE2 2.89Å; S460-H600 PolarHBondContact OG-NE2 2.85Å; S460-H600 VanDerWaalsContact OG-NE2 3.11Å
461A81Confident87Confident45 Ų4522 Ų2237%0.37214%0.139SC..Hα-helixtrans-55.8-39.3175.400000113.4N465 A498A461-N465 VanDerWaalsContact O-CB 3.26Å; A461-N465 WeakPolarHBondContact O-CB 3.45Å; A461-N465 VanDerWaalsContact O-CG 3.29Å; A461-N465 PolarHBondContact O-N 3.33Å; A461-N465 PolarHBondContact O-ND2 3.48Å; A461-A498 VanDerWaalsContact CA-CB 3.4Å; A461-A498 HydrophobicContact CB-CB 3.31Å
462E84.4Confident86.7Confident105 Ų10522.3 Ų22.349%0.49114%0.142SC..Hα-helixtrans-63.1-44.9179.9-174.7173.1179.600111.2Y394 S460 F466Y394-E462 HydrophobicContact CE2-CG 4.4Å; Y394-E462 PolarHBondContact OH-OE1 3.47Å; S460-E462 PolarHBondContact O-N 3.01Å; E462-F466 VanDerWaalsContact O-CB 3.32Å; E462-F466 WeakPolarHBondContact O-CB 3.49Å; E462-F466 PolarHBondContact O-N 2.72Å
463V85.7Confident86.5Confident4 Ų422.3 Ų22.32%0.02414%0.142CC..Hα-helixtrans-72.9-42-178.7175.10000111M390 N391 Y394 V459 S460 N465 F466 F467M390-V463 HydrophobicContact CB-CG1 3.68Å; M390-V463 HydrophobicContact CE-CG1 4.37Å; N391-V463 WeakPolarHBondContact OD1-CG2 3.41Å; Y394-V463 HydrophobicContact CD1-CG2 4.03Å; Y394-V463 HydrophobicContact CD2-CG2 4.37Å; Y394-V463 HydrophobicContact CG-CG2 3.93Å; V459-V463 HydrophobicContact CG1-CB 3.94Å; V459-V463 HydrophobicContact CG1-CG1 3.85Å; S460-V463 PolarHBondContact O-N 3.22Å; S460-V463 WeakPolarHBondContact OG-CG2 3.4Å; S460-V463 PolarHBondContact OG-N 3.46Å; V463-N465 PolarHBondContact O-N 2.86Å; V463-F466 WeakPolarHBondContact O-CB 3.24Å; V463-F466 PolarHBondContact O-N 3.11Å; V463-F467 HydrophobicContact CG1-CD2 4.17Å; V463-F467 HydrophobicContact CG1-CE2 4.19Å; V463-F467 WeakPolarHBondContact O-CD2 3.04Å; V463-F467 PolarHBondContact O-N 2.95Å
464L89.7Confident86.4Confident1 Ų122 Ų221%0.00514%0.141CC..Hα-helixtrans-57.9-49.6173.8-72.6170000111.6M390 V459 S460 F466 F467 R468 V475 E477 A498M390-L464 HydrophobicContact CE-CD2 4.21Å; V459-L464 HydrophobicContact CB-CD1 4.25Å; V459-L464 HydrophobicContact CB-CD2 3.96Å; V459-L464 HydrophobicContact CB-CG 3.88Å; V459-L464 HydrophobicContact CG1-CD2 3.95Å; V459-L464 HydrophobicContact CG1-CG 3.74Å; V459-L464 HydrophobicContact CG2-CD2 4.33Å; S460-L464 WeakPolarHBondContact O-CG 3.44Å; S460-L464 PolarHBondContact O-N 3.31Å; L464-F466 VanDerWaalsContact C-N 3.32Å; L464-F466 PolarHBondContact O-N 2.89Å; L464-F467 PolarHBondContact O-N 3.22Å; L464-F467 VanDerWaalsContact O-N 3.14Å; L464-R468 WeakPolarHBondContact O-CG 3.38Å; L464-R468 PolarHBondContact O-N 3.09Å; L464-V475 HydrophobicContact CD2-CG1 4.02Å; L464-E477 WeakPolarHBondContact CD1-OE2 3.12Å; L464-A498 HydrophobicContact CD1-CB 3.99Å
465N89.4Confident86.4Confident51 Ų5122.2 Ų22.227%0.27314%0.142SC..Hα-helixtrans-66.1-36.4179.7-74-29.8000112A461 V463 F467 R468 I469A461-N465 VanDerWaalsContact O-CB 3.26Å; A461-N465 WeakPolarHBondContact O-CB 3.45Å; A461-N465 VanDerWaalsContact O-CG 3.29Å; A461-N465 PolarHBondContact O-N 3.33Å; A461-N465 PolarHBondContact O-ND2 3.48Å; V463-N465 PolarHBondContact O-N 2.86Å; N465-F467 VanDerWaalsContact C-N 3.35Å; N465-F467 PolarHBondContact O-N 3.48Å; N465-R468 PolarHBondContact O-N 3.11Å; N465-R468 PolarHBondContact OD1-NH1 3.1Å; N465-I469 WeakPolarHBondContact O-CB 3.24Å; N465-I469 WeakPolarHBondContact O-CD1 3.39Å; N465-I469 VanDerWaalsContact O-CG1 3.24Å; N465-I469 WeakPolarHBondContact O-CG1 3.36Å; N465-I469 PolarHBondContact O-N 3.32Å
466F91.8Very high86.8Confident0 Ų022 Ų220%014%0.139CC..Hα-helixtrans-55.7-48.2169.7167-101.2000112.1V393 Y394 V397 F411 M415 E462 V463 L464 I469 C470V393-F466 HydrophobicContact CG1-CE1 4.34Å; Y394-F466 HydrophobicContact CD2-CB 3.73Å; Y394-F466 AromaticContact CD2-CD1 3.57Å; Y394-F466 HydrophobicContact CD2-CD1 3.57Å; Y394-F466 AromaticContact CD2-CD2 3.99Å; Y394-F466 HydrophobicContact CD2-CD2 3.99Å; Y394-F466 HydrophobicContact CD2-CE1 4.18Å; Y394-F466 AromaticContact CD2-CG 3.46Å; Y394-F466 HydrophobicContact CD2-CG 3.46Å; Y394-F466 VanDerWaalsContact CD2-CG 3.46Å; Y394-F466 HydrophobicContact CE2-CB 3.85Å; Y394-F466 HydrophobicContact CE2-CD1 4.44Å; Y394-F466 HydrophobicContact CE2-CD2 4.17Å; Y394-F466 AromaticContact CE2-CG 3.89Å; Y394-F466 HydrophobicContact CE2-CG 3.89Å; Y394-F466 HydrophobicContact CG-CD1 4.42Å; V397-F466 HydrophobicContact CB-CE2 4.32Å; V397-F466 HydrophobicContact CB-CZ 3.95Å; V397-F466 HydrophobicContact CG1-CE2 3.93Å; V397-F466 HydrophobicContact CG1-CZ 4Å; V397-F466 HydrophobicContact CG2-CZ 3.98Å; F411-F466 HydrophobicContact CE2-CE2 4.4Å; F411-F466 HydrophobicContact CZ-CD2 4.14Å; F411-F466 AromaticContact CZ-CE2 3.87Å; F411-F466 HydrophobicContact CZ-CE2 3.87Å; M415-F466 HydrophobicContact CE-CB 4.09Å; M415-F466 HydrophobicContact CE-CD2 4.1Å; M415-F466 HydrophobicContact SD-CD2 4.17Å; E462-F466 VanDerWaalsContact O-CB 3.32Å; E462-F466 WeakPolarHBondContact O-CB 3.49Å; E462-F466 PolarHBondContact O-N 2.72Å; V463-F466 WeakPolarHBondContact O-CB 3.24Å; V463-F466 PolarHBondContact O-N 3.11Å; L464-F466 VanDerWaalsContact C-N 3.32Å; L464-F466 PolarHBondContact O-N 2.89Å; F466-I469 PolarHBondContact O-N 3.42Å; F466-C470 HydrophobicContact CD2-CB 4.33Å; F466-C470 HydrophobicContact CE2-CB 3.98Å; F466-C470 HydrophobicContact CZ-CB 4.14Å; F466-C470 WeakPolarHBondContact O-CB 3.45Å; F466-C470 PolarHBondContact O-N 3.31Å
467F93.3Very high87.7Confident1 Ų118.5 Ų18.50%0.00411%0.114CC..Hα-helixtrans-63.2-47178-88.9-109.8000111.9M390 V393 I452 V463 L464 N465 I469 C470 F471 V475M390-F467 HydrophobicContact CB-CD2 4.39Å; M390-F467 HydrophobicContact CB-CE2 3.7Å; M390-F467 HydrophobicContact CB-CZ 3.85Å; M390-F467 HydrophobicContact CE-CB 3.96Å; M390-F467 HydrophobicContact CE-CD1 3.8Å; M390-F467 HydrophobicContact CE-CD2 3.55Å; M390-F467 HydrophobicContact CE-CE1 4.18Å; M390-F467 HydrophobicContact CE-CE2 3.99Å; M390-F467 HydrophobicContact CE-CG 3.48Å; M390-F467 VanDerWaalsContact CE-CG 3.48Å; M390-F467 HydrophobicContact CE-CZ 4.29Å; M390-F467 HydrophobicContact CG-CE1 4.22Å; M390-F467 HydrophobicContact CG-CE2 4.12Å; M390-F467 HydrophobicContact CG-CZ 3.91Å; M390-F467 WeakPolarHBondContact O-CE2 3.49Å; V393-F467 HydrophobicContact CB-CE2 4.36Å; V393-F467 HydrophobicContact CB-CZ 3.9Å; V393-F467 HydrophobicContact CG1-CE2 4.4Å; V393-F467 HydrophobicContact CG1-CZ 3.97Å; V393-F467 HydrophobicContact CG2-CZ 4.42Å; I452-F467 HydrophobicContact CD1-CD1 3.8Å; I452-F467 HydrophobicContact CD1-CE1 4.49Å; V463-F467 HydrophobicContact CG1-CD2 4.17Å; V463-F467 HydrophobicContact CG1-CE2 4.19Å; V463-F467 WeakPolarHBondContact O-CD2 3.04Å; V463-F467 PolarHBondContact O-N 2.95Å; L464-F467 PolarHBondContact O-N 3.22Å; L464-F467 VanDerWaalsContact O-N 3.14Å; N465-F467 VanDerWaalsContact C-N 3.35Å; N465-F467 PolarHBondContact O-N 3.48Å; F467-I469 VanDerWaalsContact C-N 3.31Å; F467-I469 PolarHBondContact O-N 2.88Å; F467-C470 PolarHBondContact O-N 2.68Å; F467-F471 HydrophobicContact CB-CD2 4.24Å; F467-F471 AromaticContact CD1-CD2 3.63Å; F467-F471 HydrophobicContact CD1-CD2 3.63Å; F467-F471 AromaticContact CD1-CE2 3.45Å; F467-F471 HydrophobicContact CD1-CE2 3.45Å; F467-F471 VanDerWaalsContact CD1-CE2 3.45Å; F467-F471 HydrophobicContact CE1-CD2 4.21Å; F467-F471 AromaticContact CE1-CE2 3.57Å; F467-F471 HydrophobicContact CE1-CE2 3.57Å; F467-F471 HydrophobicContact CE1-CZ 4.38Å; F467-F471 HydrophobicContact CG-CD2 4.08Å; F467-F471 HydrophobicContact CG-CE2 4.03Å; F467-F471 HydrophobicContact CZ-CE2 4.21Å; F467-F471 WeakPolarHBondContact O-CB 3.46Å; F467-F471 WeakPolarHBondContact O-CD2 3.5Å; F467-F471 PolarHBondContact O-N 2.95Å; F467-V475 HydrophobicContact CB-CG1 4.36Å; F467-V475 HydrophobicContact CB-CG2 3.95Å
468R92.4Very high88.6Confident9 Ų917 Ų173%0.03410%0.104CC..Hα-helixtrans-55-46.7177.6-69.3171.2-179.8160.9-9.4111.6V422 L464 N465 A472 V475 D495 D496V422-R468 HydrophobicContact CG1-CB 4.23Å; V422-R468 HydrophobicContact CG2-CB 4.22Å; L464-R468 WeakPolarHBondContact O-CG 3.38Å; L464-R468 PolarHBondContact O-N 3.09Å; N465-R468 PolarHBondContact O-N 3.11Å; N465-R468 PolarHBondContact OD1-NH1 3.1Å; R468-A472 WeakPolarHBondContact O-CA 3.24Å; R468-A472 PolarHBondContact O-N 3.45Å; R468-V475 HydrophobicContact CB-CG2 4.28Å; R468-V475 HydrophobicContact CG-CB 3.61Å; R468-V475 HydrophobicContact CG-CG2 3.58Å; R468-V475 PolarHBondContact NE-O 2.96Å; R468-D495 PolarHBondContact NH2-O 3.45Å; R468-D496 VanDerWaalsContact NH1-C 3.29Å; R468-D496 PolarHBondContact NH1-O 2.98Å
469I91.6Very high89.6Confident8 Ų815.1 Ų15.14%0.0419%0.09CC..Hα-helixtrans-70.9-49.7-178-71.1163.1000111.8M415 K418 V422 F438 N465 F466 F467M415-I469 HydrophobicContact CE-CB 4.23Å; M415-I469 HydrophobicContact CE-CD1 3.59Å; M415-I469 HydrophobicContact CE-CG2 4.28Å; M415-I469 WeakPolarHBondContact O-CD1 3.35Å; M415-I469 HydrophobicContact SD-CB 4.09Å; M415-I469 HydrophobicContact SD-CD1 4.25Å; M415-I469 HydrophobicContact SD-CG2 3.54Å; M415-I469 VanDerWaalsContact SD-CG2 3.54Å; K418-I469 HydrophobicContact CB-CB 4.37Å; K418-I469 HydrophobicContact CB-CG1 4.25Å; K418-I469 HydrophobicContact CB-CG2 3.53Å; K418-I469 HydrophobicContact CD-CG2 4.12Å; K418-I469 HydrophobicContact CG-CG2 4.35Å; K418-I469 PolarHBondContact NZ-O 3.45Å; V422-I469 HydrophobicContact CG2-CG1 3.89Å; F438-I469 HydrophobicContact CE1-CG2 3.99Å; F438-I469 HydrophobicContact CE2-CG2 3.92Å; F438-I469 HydrophobicContact CZ-CG2 3.49Å; F438-I469 VanDerWaalsContact CZ-CG2 3.49Å; N465-I469 WeakPolarHBondContact O-CB 3.24Å; N465-I469 WeakPolarHBondContact O-CD1 3.39Å; N465-I469 VanDerWaalsContact O-CG1 3.24Å; N465-I469 WeakPolarHBondContact O-CG1 3.36Å; N465-I469 PolarHBondContact O-N 3.32Å; F466-I469 PolarHBondContact O-N 3.42Å; F467-I469 VanDerWaalsContact C-N 3.31Å; F467-I469 PolarHBondContact O-N 2.88Å
470C91.4Very high90.4Very high0 Ų016 Ų160%010%0.101CC..Hα-helixtrans-69.3-48.9-171.2-176.70000111.5F438 V441 R442 F466 F467F438-C470 HydrophobicContact CD1-CB 4.01Å; F438-C470 HydrophobicContact CE1-CB 4.34Å; V441-C470 VanDerWaalsContact CB-SG 3.54Å; V441-C470 WeakPolarHBondContact CG1-SG 3.49Å; R442-C470 WeakPolarHBondContact CD-O 3.35Å; R442-C470 VanDerWaalsContact CG-O 3.23Å; R442-C470 WeakPolarHBondContact CG-O 3.5Å; R442-C470 PolarHBondContact NH1-O 2.88Å; F466-C470 HydrophobicContact CD2-CB 4.33Å; F466-C470 HydrophobicContact CE2-CB 3.98Å; F466-C470 HydrophobicContact CZ-CB 4.14Å; F466-C470 WeakPolarHBondContact O-CB 3.45Å; F466-C470 PolarHBondContact O-N 3.31Å; F467-C470 PolarHBondContact O-N 2.68Å
471F91.8Very high91.3Very high3 Ų316.8 Ų16.81%0.01310%0.102CC..Hα-helixtrans-82.9-16.9179.7-64.6-73.8000113.1K429 R442 F445 L449 I452 F467 C473K429-F471 VanDerWaalsContact CE-O 3.29Å; K429-F471 WeakPolarHBondContact CE-O 3.22Å; R442-F471 WeakPolarHBondContact CD-O 3.37Å; R442-F471 HydrophobicContact CG-CD1 4.02Å; F445-F471 HydrophobicContact CB-CE1 3.82Å; F445-F471 HydrophobicContact CD1-CE1 4.34Å; F445-F471 HydrophobicContact CD1-CZ 4.29Å; F445-F471 AromaticContact CD2-CE1 3.39Å; F445-F471 HydrophobicContact CD2-CE1 3.39Å; F445-F471 AromaticContact CD2-CZ 3.56Å; F445-F471 HydrophobicContact CD2-CZ 3.56Å; F445-F471 HydrophobicContact CE1-CZ 4.4Å; F445-F471 HydrophobicContact CE2-CE1 4.02Å; F445-F471 AromaticContact CE2-CZ 3.68Å; F445-F471 HydrophobicContact CE2-CZ 3.68Å; F445-F471 AromaticContact CG-CE1 3.59Å; F445-F471 HydrophobicContact CG-CE1 3.59Å; F445-F471 AromaticContact CG-CZ 3.89Å; F445-F471 HydrophobicContact CG-CZ 3.89Å; F445-F471 HydrophobicContact CZ-CZ 4.11Å; L449-F471 HydrophobicContact CD1-CD1 3.88Å; L449-F471 HydrophobicContact CD1-CE1 4.17Å; L449-F471 HydrophobicContact CD1-CG 4.44Å; I452-F471 HydrophobicContact CD1-CB 4.26Å; I452-F471 HydrophobicContact CD1-CD2 3.97Å; I452-F471 HydrophobicContact CD1-CG 4.11Å; F467-F471 HydrophobicContact CB-CD2 4.24Å; F467-F471 AromaticContact CD1-CD2 3.63Å; F467-F471 HydrophobicContact CD1-CD2 3.63Å; F467-F471 AromaticContact CD1-CE2 3.45Å; F467-F471 HydrophobicContact CD1-CE2 3.45Å; F467-F471 VanDerWaalsContact CD1-CE2 3.45Å; F467-F471 HydrophobicContact CE1-CD2 4.21Å; F467-F471 AromaticContact CE1-CE2 3.57Å; F467-F471 HydrophobicContact CE1-CE2 3.57Å; F467-F471 HydrophobicContact CE1-CZ 4.38Å; F467-F471 HydrophobicContact CG-CD2 4.08Å; F467-F471 HydrophobicContact CG-CE2 4.03Å; F467-F471 HydrophobicContact CZ-CE2 4.21Å; F467-F471 WeakPolarHBondContact O-CB 3.46Å; F467-F471 WeakPolarHBondContact O-CD2 3.5Å; F467-F471 PolarHBondContact O-N 2.95Å; F471-C473 HydrophobicContact CB-CB 4.31Å; F471-C473 WeakPolarHBondContact CB-SG 3.46Å; F471-C473 PolarHBondContact O-N 2.91Å
472A89.9Confident91.8Very high10 Ų1016.2 Ų16.28%0.0839%0.094CC..  trans51.344.9-177.500000111.5R428 K429 R468R428-A472 VanDerWaalsContact O-CB 3.32Å; R428-A472 WeakPolarHBondContact O-CB 3.3Å; K429-A472 HydrophobicContact CG-CB 3.59Å; R468-A472 WeakPolarHBondContact O-CA 3.24Å; R468-A472 PolarHBondContact O-N 3.45Å
473C91.3Very high92.4Very high1 Ų111.9 Ų11.91%0.0077%0.074CC..SBendtrans-133.9163.5-175.572.60000109.4L427 S450 I452 F471 V475L427-C473 WeakPolarHBondContact CD1-O 3.42Å; S450-C473 WeakPolarHBondContact O-CB 3.35Å; I452-C473 WeakPolarHBondContact CD1-SG 3.35Å; I452-C473 VanDerWaalsContact CG1-SG 3.59Å; F471-C473 HydrophobicContact CB-CB 4.31Å; F471-C473 WeakPolarHBondContact CB-SG 3.46Å; F471-C473 PolarHBondContact O-N 2.91Å; C473-V475 PolarHBondContact O-N 2.75Å
474V93Very high93Very high4 Ų411.7 Ų11.72%0.0247%0.073CC..EExtended strand (participates in β ladder)trans-66.2133.9174174.50000108.2I41 H328 L427 S450 L451 I452 C476 E493I41-V474 HydrophobicContact CD1-CG2 4.17Å; H328-V474 WeakPolarHBondContact CE1-CG2 3.48Å; H328-V474 VanDerWaalsContact ND1-CG2 3.32Å; H328-V474 WeakPolarHBondContact ND1-CG2 3.45Å; L427-V474 HydrophobicContact CD1-CG2 3.96Å; S450-V474 PolarHBondContact O-N 3.47Å; L451-V474 HydrophobicContact CD1-CB 3.93Å; L451-V474 HydrophobicContact CD1-CG1 3.71Å; I452-V474 PolarHBondContact N-O 3.05Å; V474-C476 VanDerWaalsContact CG1-SG 3.53Å; V474-E493 HydrophobicContact CG1-CB 4.29Å; V474-E493 HydrophobicContact CG1-CG 4.09Å; V474-E493 HydrophobicContact CG2-CB 4.37Å; V474-E493 HydrophobicContact CG2-CG 4.48Å
475V94.5Very high93.3Very high4 Ų411.7 Ų11.72%0.0247%0.073CC..EExtended strand (participates in β ladder)trans-128.2110.6174.3-172.80000107.4M390 I452 L464 F467 R468 C473M390-V475 HydrophobicContact CE-CG1 4.32Å; I452-V475 HydrophobicContact CB-CG1 4.35Å; I452-V475 HydrophobicContact CB-CG2 4.22Å; I452-V475 HydrophobicContact CD1-CG2 4.45Å; I452-V475 HydrophobicContact CG2-CG1 4.27Å; I452-V475 VanDerWaalsContact O-CA 3.3Å; I452-V475 WeakPolarHBondContact O-CA 3.36Å; L464-V475 HydrophobicContact CD2-CG1 4.02Å; F467-V475 HydrophobicContact CB-CG1 4.36Å; F467-V475 HydrophobicContact CB-CG2 3.95Å; R468-V475 HydrophobicContact CB-CG2 4.28Å; R468-V475 HydrophobicContact CG-CB 3.61Å; R468-V475 HydrophobicContact CG-CG2 3.58Å; R468-V475 PolarHBondContact NE-O 2.96Å; C473-V475 PolarHBondContact O-N 2.75Å
476C94.8Very high93.6Very high0 Ų010 Ų100%07%0.066CC..EExtended strand (participates in β ladder)trans-105.8145.1178.5-64.70000110.5I452 S454 V474 L490 T491I452-C476 PolarHBondContact O-N 2.93Å; S454-C476 PolarHBondContact N-O 3.07Å; V474-C476 VanDerWaalsContact CG1-SG 3.53Å; C476-L490 HydrophobicContact CB-CD1 3.78Å; C476-L490 HydrophobicContact CB-CG 4.23Å; C476-T491 WeakPolarHBondContact CA-OG1 3.5Å; C476-T491 WeakPolarHBondContact CB-OG1 3.35Å; C476-T491 PolarHBondContact SG-O 3.5Å
477E94Very high93.9Very high7 Ų710.8 Ų10.83%0.0337%0.072CC..EExtended strand (participates in β ladder)trans-109.7127.1169.6-168.6175.3-165.700108.5S454 V459 L464 T491 V501S454-E477 WeakPolarHBondContact O-CA 3.36Å; V459-E477 PolarHBondContact N-OE1 3.03Å; L464-E477 WeakPolarHBondContact CD1-OE2 3.12Å; E477-T491 HydrophobicContact CB-CG2 4.25Å; E477-T491 PolarHBondContact N-OG1 2.99Å; E477-T491 PolarHBondContact O-N 2.86Å; E477-T491 PolarHBondContact O-OG1 2.74Å; E477-V501 HydrophobicContact CG-CG1 4.24Å
478G93.5Very high94.1Very high18 Ų1810.7 Ų10.719%0.1867%0.072CC..EExtended strand (participates in β ladder)trans-115.6146.9-17900000112S454 S489S454-G478 PolarHBondContact O-N 3.48Å; G478-S489 WeakPolarHBondContact CA-O 3.49Å
479Y95.2Very high94.3Very high16 Ų1610.3 Ų10.36%0.0637%0.07CC..EExtended strand (participates in β ladder)trans-119.5145.4171.7163.9-104.6000110.5A488 S489 V501 I529 D561 L571 L573Y479-A488 HydrophobicContact CD1-CB 3.99Å; Y479-A488 HydrophobicContact CE1-CB 4.13Å; Y479-A488 WeakPolarHBondContact O-CA 3.15Å; Y479-A488 WeakPolarHBondContact O-CB 3.45Å; Y479-A488 PolarHBondContact O-N 2.75Å; Y479-S489 PolarHBondContact N-O 3.23Å; Y479-S489 PolarHBondContact O-N 2.92Å; Y479-V501 HydrophobicContact CG-CG2 4.33Å; Y479-I529 HydrophobicContact CE1-CD1 4.2Å; Y479-I529 HydrophobicContact CE1-CG2 4.13Å; Y479-D561 HydrophobicContact CE2-CB 4.5Å; Y479-D561 WeakPolarHBondContact CE2-OD2 3.48Å; Y479-D561 PolarHBondContact OH-OD2 2.68Å; Y479-L571 HydrophobicContact CD1-CD2 3.98Å; Y479-L571 HydrophobicContact CE1-CD2 4.27Å; Y479-L573 HydrophobicContact CD1-CD2 4.16Å; Y479-L573 HydrophobicContact CD2-CD1 3.46Å; Y479-L573 VanDerWaalsContact CD2-CD1 3.46Å; Y479-L573 HydrophobicContact CD2-CD2 3.77Å; Y479-L573 HydrophobicContact CD2-CG 4.22Å; Y479-L573 HydrophobicContact CE1-CD2 4.3Å; Y479-L573 HydrophobicContact CE2-CD1 4.12Å; Y479-L573 HydrophobicContact CE2-CD2 3.9Å; Y479-L573 HydrophobicContact CG-CD1 3.96Å; Y479-L573 HydrophobicContact CG-CD2 3.9Å; Y479-L573 HydrophobicContact CG-CG 4.42Å
480G94.3Very high94.6Very high29 Ų2910.5 Ų10.530%0.2997%0.072SC..  trans167.1-171168.600000111A486G480-A486 CarbonylContact C-O 3.54Å; G480-A486 WeakPolarHBondContact CA-O 3.17Å
481Q93.6Very high94.8Very high36 Ų3610.7 Ų10.717%0.1687%0.073CC..  trans-146.9168-173.457.3179.9-28.700110.6E483 C484 V485Q481-E483 HydrophobicContact CG-CB 4.16Å; Q481-E483 PolarHBondContact O-N 2.72Å; Q481-C484 PolarHBondContact N-SG 2.97Å; Q481-C484 VanDerWaalsContact N-SG 3.41Å; Q481-C484 CarbonylContact O-C 3.49Å; Q481-C484 PolarHBondContact O-N 2.72Å; Q481-C484 VanDerWaalsContact O-N 3.11Å; Q481-C484 PolarHBondContact O-SG 3.03Å; Q481-V485 CarbonylContact O-C 3.59Å
482T92.9Very high94.9Very high34 Ų3410.7 Ų10.721%0.2097%0.073CC..G310 helixtrans-60.5-36.4-179.4-52.50000111.5C296 V308 M345 C484 V485C296-T482 HydrophobicContact CB-CG2 3.55Å; V308-T482 HydrophobicContact CB-CG2 3.89Å; V308-T482 HydrophobicContact CG1-CG2 4.04Å; V308-T482 HydrophobicContact CG2-CG2 3.89Å; M345-T482 HydrophobicContact CG-CG2 4.1Å; T482-C484 PolarHBondContact O-N 3.23Å; T482-C484 VanDerWaalsContact O-N 3.15Å; T482-V485 PolarHBondContact O-N 3.33Å
483E96.6Very high95Very high14 Ų1410.3 Ų10.37%0.0657%0.069CC..G310 helixtrans-64.2-11.3178-67.786.6160.800114.4V308 Q481 F537 Y540 L557V308-E483 HydrophobicContact CG1-CG 4.35Å; V308-E483 HydrophobicContact CG2-CG 4.04Å; Q481-E483 HydrophobicContact CG-CB 4.16Å; Q481-E483 PolarHBondContact O-N 2.72Å; E483-F537 HydrophobicContact CB-CD1 3.96Å; E483-F537 HydrophobicContact CB-CD2 4.28Å; E483-F537 HydrophobicContact CB-CE1 4.05Å; E483-F537 HydrophobicContact CB-CE2 4.32Å; E483-F537 HydrophobicContact CB-CG 4.09Å; E483-F537 HydrophobicContact CB-CZ 4.22Å; E483-F537 HydrophobicContact CG-CD1 4.44Å; E483-F537 HydrophobicContact CG-CD2 4.04Å; E483-F537 HydrophobicContact CG-CE1 4.23Å; E483-F537 HydrophobicContact CG-CE2 3.75Å; E483-F537 HydrophobicContact CG-CG 4.36Å; E483-F537 HydrophobicContact CG-CZ 3.86Å; E483-F537 VanDerWaalsContact O-CB 3.31Å; E483-F537 WeakPolarHBondContact O-CB 3.46Å; E483-F537 VanDerWaalsContact O-CD1 3.26Å; E483-F537 WeakPolarHBondContact O-CD1 3.33Å; E483-F537 WeakPolarHBondContact O-CG 3.45Å; E483-F537 PolarHBondContact O-N 3.37Å; E483-Y540 HydrophobicContact CG-CE1 3.96Å; E483-Y540 WeakPolarHBondContact OE1-CE1 2.74Å; E483-Y540 PolarHBondContact OE1-OH 3.24Å; E483-L557 HydrophobicContact CB-CD1 4.41Å; E483-L557 HydrophobicContact CB-CD2 3.65Å
484C97.2Very high94.7Very high0 Ų011 Ų110%08%0.076CC..G310 helixtrans-124.835.1171.771.80000111.4Q481 T482 A486 L531 N535 L557Q481-C484 PolarHBondContact N-SG 2.97Å; Q481-C484 VanDerWaalsContact N-SG 3.41Å; Q481-C484 CarbonylContact O-C 3.49Å; Q481-C484 PolarHBondContact O-N 2.72Å; Q481-C484 VanDerWaalsContact O-N 3.11Å; Q481-C484 PolarHBondContact O-SG 3.03Å; T482-C484 PolarHBondContact O-N 3.23Å; T482-C484 VanDerWaalsContact O-N 3.15Å; C484-A486 PolarHBondContact O-N 3.35Å; C484-L531 HydrophobicContact CB-CD1 3.78Å; C484-N535 CarbonylContact C-O 3.55Å; C484-N535 VanDerWaalsContact C-O 3.32Å; C484-N535 WeakPolarHBondContact CA-O 3.39Å; C484-N535 PolarHBondContact O-ND2 3.28Å; C484-L557 HydrophobicContact CB-CD2 4.44Å
485V97.6Very high94.6Very high0 Ų010.9 Ų10.90%08%0.076CC..SBendtrans66.5-83.8-170.2175.30000110.6L310 N314 I315 D318 M345 L349 Q481 T482L310-V485 HydrophobicContact CD1-CG2 4.25Å; L310-V485 HydrophobicContact CD2-CG2 3.86Å; N314-V485 HydrophobicContact CB-CG2 3.84Å; I315-V485 HydrophobicContact CG1-CG1 4.18Å; I315-V485 HydrophobicContact CG1-CG2 3.93Å; D318-V485 HydrophobicContact CB-CB 3.81Å; D318-V485 HydrophobicContact CB-CG1 3.73Å; D318-V485 HydrophobicContact CB-CG2 4.33Å; D318-V485 VanDerWaalsContact OD2-CB 3.26Å; D318-V485 WeakPolarHBondContact OD2-CB 3.37Å; D318-V485 VanDerWaalsContact OD2-CG1 3.25Å; D318-V485 WeakPolarHBondContact OD2-CG1 3.36Å; M345-V485 WeakPolarHBondContact CB-O 3.44Å; M345-V485 HydrophobicContact CE-CG1 3.68Å; M345-V485 VanDerWaalsContact CG-O 3.31Å; M345-V485 WeakPolarHBondContact CG-O 3.3Å; L349-V485 HydrophobicContact CD1-CG1 4.3Å; Q481-V485 CarbonylContact O-C 3.59Å; T482-V485 PolarHBondContact O-N 3.33Å
486A95.3Very high94.2Very high17 Ų1712.8 Ų12.814%0.149%0.085CC..SBendtrans-150.5-38.7173.500000114.2D318 M345 L349 G480 C484D318-A486 PolarHBondContact OD2-N 2.89Å; M345-A486 HydrophobicContact CB-CB 4.07Å; L349-A486 HydrophobicContact CB-CB 4.21Å; L349-A486 HydrophobicContact CD2-CB 3.91Å; G480-A486 CarbonylContact C-O 3.54Å; G480-A486 WeakPolarHBondContact CA-O 3.17Å; C484-A486 PolarHBondContact O-N 3.35Å
487A96.9Very high93.9Very high15 Ų1514.7 Ų14.712%0.12410%0.097CC..  trans-111.5102.6-168.800000112.3D318 V321 L349 C505 N508D318-A487 PolarHBondContact OD2-N 3.24Å; V321-A487 HydrophobicContact CG2-CB 4.31Å; L349-A487 HydrophobicContact CD2-CB 3.9Å; A487-C505 PolarHBondContact O-SG 3.43Å; A487-N508 PolarHBondContact O-ND2 2.83Å; A487-N508 VanDerWaalsContact O-ND2 3.08Å
488A98Very high93.4Very high0 Ų015.3 Ų15.30%010%0.103CC..SBendtrans-84.7-42.4170.200000111.8Y479 C505 L531Y479-A488 HydrophobicContact CD1-CB 3.99Å; Y479-A488 HydrophobicContact CE1-CB 4.13Å; Y479-A488 WeakPolarHBondContact O-CA 3.15Å; Y479-A488 WeakPolarHBondContact O-CB 3.45Å; Y479-A488 PolarHBondContact O-N 2.75Å; A488-C505 PolarHBondContact O-N 3.21Å; A488-L531 HydrophobicContact CB-CD1 3.69Å; A488-L531 HydrophobicContact CB-CD2 3.87Å; A488-L531 HydrophobicContact CB-CG 4.46Å
489S97.9Very high92.7Very high0 Ų016.3 Ų16.30%011%0.114CC..EExtended strand (participates in β ladder)trans-144154.717972.50000111.3G478 Y479 V501 P503G478-S489 WeakPolarHBondContact CA-O 3.49Å; Y479-S489 PolarHBondContact N-O 3.23Å; Y479-S489 PolarHBondContact O-N 2.92Å; S489-V501 CarbonylContact C-O 3.45Å; S489-V501 VanDerWaalsContact C-O 3.25Å; S489-V501 WeakPolarHBondContact CB-O 3.37Å; S489-V501 WeakPolarHBondContact OG-CG2 3.08Å; S489-V501 PolarHBondContact OG-O 2.95Å; S489-P503 VanDerWaalsContact CA-O 3.27Å; S489-P503 WeakPolarHBondContact CA-O 3.35Å; S489-P503 WeakPolarHBondContact CB-O 3.37Å
490L97.1Very high92.5Very high13 Ų1315.7 Ų15.77%0.06811%0.111CC..EExtended strand (participates in β ladder)trans-148.6131.5-179.2-175.770.8000111.3V321 A324 F325 I453 C476 V501 P503V321-L490 HydrophobicContact CG2-CB 4.31Å; V321-L490 HydrophobicContact CG2-CD2 3.72Å; A324-L490 HydrophobicContact CB-CD2 4.39Å; F325-L490 HydrophobicContact CE1-CD2 4.07Å; F325-L490 HydrophobicContact CE2-CD2 4.35Å; F325-L490 HydrophobicContact CZ-CD2 3.6Å; I453-L490 HydrophobicContact CG2-CD1 4.28Å; C476-L490 HydrophobicContact CB-CD1 3.78Å; C476-L490 HydrophobicContact CB-CG 4.23Å; L490-V501 CarbonylContact C-O 3.5Å; L490-V501 WeakPolarHBondContact CA-O 3.19Å; L490-V501 PolarHBondContact N-O 3.15Å; L490-V501 VanDerWaalsContact N-O 3.08Å; L490-P503 PolarHBondContact N-O 2.67Å; L490-P503 WeakPolarHBondContact O-CD 3.38Å
491T95.7Very high92.5Very high3 Ų314.6 Ų14.62%0.01810%0.099CC..PPolyproline II helixtrans-61.8144.917358.70000112.1C476 E477 Q500C476-T491 WeakPolarHBondContact CA-OG1 3.5Å; C476-T491 WeakPolarHBondContact CB-OG1 3.35Å; C476-T491 PolarHBondContact SG-O 3.5Å; E477-T491 HydrophobicContact CB-CG2 4.25Å; E477-T491 PolarHBondContact N-OG1 2.99Å; E477-T491 PolarHBondContact O-N 2.86Å; E477-T491 PolarHBondContact O-OG1 2.74Å; T491-Q500 HydrophobicContact CG2-CG 4.45Å; T491-Q500 VanDerWaalsContact CG2-O 3.29Å; T491-Q500 WeakPolarHBondContact CG2-O 3.4Å
492L94Very high92.6Very high4 Ų412.9 Ų12.92%0.0219%0.091CC..PPolyproline II helixtrans-76.3156-177.2-53.7-174.8000113.3Y44 V45 L48 Q51 G494 D495 P503Y44-L492 HydrophobicContact CD1-CD2 4.49Å; Y44-L492 HydrophobicContact CE1-CD2 3.41Å; Y44-L492 VanDerWaalsContact CE1-CD2 3.41Å; Y44-L492 HydrophobicContact CE2-CD2 4.46Å; Y44-L492 VanDerWaalsContact CZ-CD2 3.41Å; Y44-L492 WeakPolarHBondContact OH-CD2 3.37Å; V45-L492 HydrophobicContact CB-CD1 4.06Å; V45-L492 HydrophobicContact CG2-CD1 3.5Å; L48-L492 HydrophobicContact CD2-CB 4.27Å; L48-L492 HydrophobicContact CD2-CD1 3.98Å; Q51-L492 HydrophobicContact CB-CD1 3.99Å; Q51-L492 HydrophobicContact CG-CD1 3.78Å; L492-G494 PolarHBondContact O-N 3.09Å; L492-D495 HydrophobicContact CB-CB 4.42Å; L492-D495 WeakPolarHBondContact O-CB 3.48Å; L492-D495 PolarHBondContact O-N 3.34Å; L492-P503 HydrophobicContact CD1-CG 4.48Å; L492-P503 HydrophobicContact CD2-CG 3.72Å; L492-P503 HydrophobicContact CG-CG 4.15Å
493E90.9Very high92.8Very high2 Ų211.3 Ų11.31%0.0098%0.081CC..THydrogen-bonded Turntrans-59135.4170.3-55.2-176.491.700110.6I41 T43 F325 C326 A327 H328 V474 D495I41-E493 HydrophobicContact CG2-CB 3.7Å; T43-E493 WeakPolarHBondContact CG2-O 3.44Å; F325-E493 VanDerWaalsContact C-OE2 3.26Å; F325-E493 WeakPolarHBondContact CA-OE2 3.05Å; F325-E493 HydrophobicContact CD1-CG 3.97Å; C326-E493 PolarHBondContact N-OE2 2.94Å; A327-E493 PolarHBondContact N-OE2 2.83Å; H328-E493 WeakPolarHBondContact CB-OE1 3.5Å; H328-E493 IonicContact CE1-OE1 2.79Å; H328-E493 IonicContact CG-OE1 3.05Å; H328-E493 PolarHBondContact N-OE1 3.09Å; H328-E493 IonicContact ND1-OE1 3.97Å; H328-E493 PolarHBondContact ND1-OE1 3.37Å; V474-E493 HydrophobicContact CG1-CB 4.29Å; V474-E493 HydrophobicContact CG1-CG 4.09Å; V474-E493 HydrophobicContact CG2-CB 4.37Å; V474-E493 HydrophobicContact CG2-CG 4.48Å; E493-D495 PolarHBondContact O-N 2.8Å
494G86.4Confident92.9Very high14 Ų1410.7 Ų10.714%0.1448%0.079CC..THydrogen-bonded Turntrans76-2.9178.400000115.3A425 L492 D496A425-G494 WeakPolarHBondContact CB-O 3.09Å; L492-G494 PolarHBondContact O-N 3.09Å; G494-D496 PolarHBondContact O-N 3.08Å
495D89.8Confident92.9Very high3 Ų310.9 Ų10.92%0.0168%0.08CC..  trans-71.7119.8168.5-166.22.7000110L48 Q51 R468 L492 E493 V497 Q500 R568L48-D495 HydrophobicContact CD2-CB 4.47Å; Q51-D495 PolarHBondContact NE2-OD2 3.07Å; Q51-D495 PolarHBondContact OE1-OD2 3.42Å; R468-D495 PolarHBondContact NH2-O 3.45Å; L492-D495 HydrophobicContact CB-CB 4.42Å; L492-D495 WeakPolarHBondContact O-CB 3.48Å; L492-D495 PolarHBondContact O-N 3.34Å; E493-D495 PolarHBondContact O-N 2.8Å; D495-V497 PolarHBondContact OD1-N 2.85Å; D495-Q500 PolarHBondContact OD2-NE2 2.86Å; D495-R568 IonicContact OD1-CZ 3.97Å; D495-R568 IonicContact OD1-NH2 3.93Å; D495-R568 PolarHBondContact OD1-NH2 3.2Å
496D87.1Confident92.9Very high43 Ų4311 Ų1123%0.238%0.08CC..  trans-93.4-12.5-178.973.8-52.1000112.8V422 K423 R468 G494V422-D496 HydrophobicContact CG1-CB 3.99Å; K423-D496 WeakPolarHBondContact CG-OD2 3.44Å; R468-D496 VanDerWaalsContact NH1-C 3.29Å; R468-D496 PolarHBondContact NH1-O 2.98Å; G494-D496 PolarHBondContact O-N 3.08Å
497V87.9Confident93Very high40 Ų4010.1 Ų10.124%0.2427%0.074CC..  trans-70141.4179.7-178.50000109.7D495 Q500D495-V497 PolarHBondContact OD1-N 2.85Å; V497-Q500 HydrophobicContact CG1-CG 4.28Å
498A83.5Confident93Very high20 Ų209.4 Ų9.417%0.1657%0.068CC..  trans-125169-178.500000111A461 L464 Q500A461-A498 VanDerWaalsContact CA-CB 3.4Å; A461-A498 HydrophobicContact CB-CB 3.31Å; L464-A498 HydrophobicContact CD1-CB 3.99Å; A498-Q500 VanDerWaalsContact C-N 3.28Å
499G79.7Confident93Very high39 Ų3910.1 Ų10.140%0.4027%0.071SC..SBendtrans71.228.6-171.100000112.2R572G499-R572 VanDerWaalsContact O-CG 3.29Å; G499-R572 WeakPolarHBondContact O-CG 3.43Å; G499-R572 PolarHBondContact O-NE 2.86Å
500Q90.7Very high93Very high3 Ų310.1 Ų10.11%0.0147%0.071CC..  trans-146.3154.1174.666.3-179.120.800108.7T491 D495 V497 A498 T570 L571T491-Q500 HydrophobicContact CG2-CG 4.45Å; T491-Q500 VanDerWaalsContact CG2-O 3.29Å; T491-Q500 WeakPolarHBondContact CG2-O 3.4Å; D495-Q500 PolarHBondContact OD2-NE2 2.86Å; V497-Q500 HydrophobicContact CG1-CG 4.28Å; A498-Q500 VanDerWaalsContact C-N 3.28Å; Q500-T570 VanDerWaalsContact CD-OG1 3.27Å; Q500-T570 PolarHBondContact OE1-OG1 3.18Å; Q500-L571 CarbonylContact C-O 2.85Å; Q500-L571 WeakPolarHBondContact CA-O 3.42Å
501V93.9Very high93Very high7 Ų710.5 Ų10.54%0.0427%0.072CC..  trans-116.321.9-175.8-650000111.9E477 Y479 S489 L490 L571 L573E477-V501 HydrophobicContact CG-CG1 4.24Å; Y479-V501 HydrophobicContact CG-CG2 4.33Å; S489-V501 CarbonylContact C-O 3.45Å; S489-V501 VanDerWaalsContact C-O 3.25Å; S489-V501 WeakPolarHBondContact CB-O 3.37Å; S489-V501 WeakPolarHBondContact OG-CG2 3.08Å; S489-V501 PolarHBondContact OG-O 2.95Å; L490-V501 CarbonylContact C-O 3.5Å; L490-V501 WeakPolarHBondContact CA-O 3.19Å; L490-V501 PolarHBondContact N-O 3.15Å; L490-V501 VanDerWaalsContact N-O 3.08Å; V501-L571 HydrophobicContact CG2-CB 3.94Å; V501-L571 HydrophobicContact CG2-CD2 4.08Å; V501-L571 HydrophobicContact CG2-CG 4.03Å; V501-L571 VanDerWaalsContact CG2-O 3.27Å; V501-L571 WeakPolarHBondContact CG2-O 3.33Å; V501-L571 PolarHBondContact N-O 3.13Å; V501-L573 HydrophobicContact CG1-CD1 4.07Å; V501-L573 HydrophobicContact CG1-CG 4.22Å; V501-L573 HydrophobicContact CG2-CD2 4.26Å; V501-L573 HydrophobicContact CG2-CG 4.02Å
502G95.6Very high93.1Very high0 Ų010.8 Ų10.80%07%0.074CC..  trans75.6-174.1172.300000115.8L571G502-L571 PolarHBondContact O-N 3.47Å
503P97.1Very high93.2Very high1 Ų112.6 Ų12.61%0.0069%0.085CC..SBendtrans-75.2168.9173.733.2-38.5000112.3Q51 S489 L490 L492Q51-P503 HydrophobicContact CB-CB 4.19Å; Q51-P503 HydrophobicContact CB-CG 4.08Å; Q51-P503 WeakPolarHBondContact O-CB 3.3Å; Q51-P503 WeakPolarHBondContact O-CG 3.05Å; S489-P503 VanDerWaalsContact CA-O 3.27Å; S489-P503 WeakPolarHBondContact CA-O 3.35Å; S489-P503 WeakPolarHBondContact CB-O 3.37Å; L490-P503 PolarHBondContact N-O 2.67Å; L490-P503 WeakPolarHBondContact O-CD 3.38Å; L492-P503 HydrophobicContact CD1-CG 4.48Å; L492-P503 HydrophobicContact CD2-CG 3.72Å; L492-P503 HydrophobicContact CG-CG 4.15Å
504P98.2Very high93.4Very high1 Ų116.1 Ų16.11%0.00610%0.104CC..BIsolated β-bridgetrans-52.4142.1172.6-25.534.4000112.9R62 S64 N508 I510 W565R62-P504 HydrophobicContact CB-CG 4.24Å; S64-P504 VanDerWaalsContact CB-O 3.31Å; S64-P504 WeakPolarHBondContact CB-O 3.28Å; P504-N508 WeakPolarHBondContact CB-O 3.16Å; P504-I510 HydrophobicContact CB-CD1 4.03Å; P504-I510 HydrophobicContact CB-CG1 3.98Å; P504-I510 HydrophobicContact CG-CB 4.14Å; P504-I510 HydrophobicContact CG-CD1 3.94Å; P504-I510 HydrophobicContact CG-CG1 3.87Å; P504-W565 HydrophobicContact CG-CH2 4.22Å
505C97.8Very high93.6Very high4 Ų415.5 Ų15.53%0.02710%0.097CC..PPolyproline II helixtrans-66.3155.1167.1-680000110.4V321 A487 A488 A507 N508V321-C505 HydrophobicContact CG2-CB 4.35Å; V321-C505 VanDerWaalsContact CG2-SG 3.52Å; A487-C505 PolarHBondContact O-SG 3.43Å; A488-C505 PolarHBondContact O-N 3.21Å; C505-A507 PolarHBondContact O-N 3.29Å; C505-N508 PolarHBondContact O-N 2.91Å
506P97.4Very high93.4Very high1 Ų118.6 Ų18.61%0.00612%0.118CC..THydrogen-bonded Turntrans-62.4-17.3-174.7-23.835.3000115.5L66 C67 L72 K73L66-P506 HydrophobicContact CB-CB 4.27Å; L66-P506 HydrophobicContact CB-CG 3.94Å; L66-P506 HydrophobicContact CD1-CG 3.53Å; L66-P506 HydrophobicContact CG-CG 4.38Å; C67-P506 PolarHBondContact SG-O 3.07Å; C67-P506 VanDerWaalsContact SG-O 3.34Å; L72-P506 WeakPolarHBondContact CD2-O 3.37Å; K73-P506 HydrophobicContact CB-CB 3.98Å; K73-P506 HydrophobicContact CD-CB 3.81Å; K73-P506 HydrophobicContact CG-CB 3.87Å; K73-P506 PolarHBondContact N-O 2.92Å
507A97.6Very high93Very high0 Ų021 Ų210%013%0.128CC..THydrogen-bonded Turntrans-92.83.717500000113.8A317 C505 G533 P534 N535A317-A507 HydrophobicContact CB-CB 4.14Å; A317-A507 VanDerWaalsContact O-CB 3.26Å; A317-A507 WeakPolarHBondContact O-CB 3.15Å; C505-A507 PolarHBondContact O-N 3.29Å; A507-G533 WeakPolarHBondContact O-CA 3.17Å; A507-P534 HydrophobicContact CB-CG 4.16Å; A507-P534 WeakPolarHBondContact O-CD 3.41Å; A507-N535 HydrophobicContact CB-CB 4.25Å; A507-N535 PolarHBondContact O-OD1 3.19Å
508N96.3Very high92.5Very high0 Ų020.1 Ų20.10%012%0.121CC..  trans-129.5141.2-177.5-71.1-87.6000113A487 P504 C505 N535A487-N508 PolarHBondContact O-ND2 2.83Å; A487-N508 VanDerWaalsContact O-ND2 3.08Å; P504-N508 WeakPolarHBondContact CB-O 3.16Å; C505-N508 PolarHBondContact O-N 2.91Å; N508-N535 VanDerWaalsContact CG-OD1 3.24Å; N508-N535 VanDerWaalsContact ND2-CG 3.33Å; N508-N535 PolarHBondContact ND2-ND2 2.98Å; N508-N535 PolarHBondContact ND2-OD1 3.4Å; N508-N535 VanDerWaalsContact OD1-CG 3.29Å; N508-N535 PolarHBondContact OD1-ND2 3.49Å; N508-N535 PolarHBondContact OD1-OD1 3.31Å
509L98Very high92.4Very high14 Ų1424.2 Ų24.27%0.07314%0.14CC..EExtended strand (participates in β ladder)trans-94.1145151.2-62171.9000109.2H55 I63 L72 L531 K532 W556H55-L509 HydrophobicContact CB-CD2 4.07Å; I63-L509 HydrophobicContact CB-CD2 3.66Å; I63-L509 HydrophobicContact CD1-CD2 3.85Å; I63-L509 HydrophobicContact CG1-CD2 3.75Å; L72-L509 HydrophobicContact CD1-CG 4.12Å; L72-L509 HydrophobicContact CD2-CD2 4.18Å; L72-L509 HydrophobicContact CD2-CG 4.13Å; L72-L509 HydrophobicContact CG-CG 4.42Å; L509-L531 WeakPolarHBondContact O-CA 3.26Å; L509-K532 HydrophobicContact CB-CB 4.49Å; L509-K532 WeakPolarHBondContact CB-O 3.3Å; L509-K532 PolarHBondContact N-O 2.85Å; L509-K532 PolarHBondContact O-N 3.5Å; L509-W556 HydrophobicContact CB-CH2 3.69Å; L509-W556 HydrophobicContact CB-CZ3 4.03Å; L509-W556 HydrophobicContact CD1-CH2 4.44Å
510I98.5Very high92.9Very high0 Ų024.7 Ų24.70%013%0.13CC..EExtended strand (participates in β ladder)trans-126.5129.5173-54.5-174.1000108.7S61 R62 P504 I529 C530 L531 W565 L571S61-I510 CarbonylContact C-O 3.45Å; S61-I510 WeakPolarHBondContact CA-O 3.35Å; R62-I510 PolarHBondContact N-O 3.49Å; R62-I510 PolarHBondContact O-N 3.28Å; R62-I510 VanDerWaalsContact O-N 3.12Å; P504-I510 HydrophobicContact CB-CD1 4.03Å; P504-I510 HydrophobicContact CB-CG1 3.98Å; P504-I510 HydrophobicContact CG-CB 4.14Å; P504-I510 HydrophobicContact CG-CD1 3.94Å; P504-I510 HydrophobicContact CG-CG1 3.87Å; I510-I529 HydrophobicContact CG2-CG2 3.86Å; I510-C530 WeakPolarHBondContact CA-O 3.19Å; I510-L531 HydrophobicContact CB-CD2 4.43Å; I510-L531 HydrophobicContact CD1-CD2 4.04Å; I510-L531 HydrophobicContact CG1-CD2 3.7Å; I510-L531 HydrophobicContact CG2-CD2 4.29Å; I510-W565 HydrophobicContact CB-CH2 3.8Å; I510-W565 HydrophobicContact CB-CZ2 3.92Å; I510-W565 HydrophobicContact CG2-CH2 3.76Å; I510-W565 HydrophobicContact CG2-CZ2 3.68Å; I510-L571 HydrophobicContact CD1-CD2 4.28Å
511K97.2Very high92.9Very high21 Ų2127.3 Ų27.39%0.09114%0.142CC..EExtended strand (participates in β ladder)trans-122.5161.6166.374.6177.7-179.7-172.20110.2V513 C530 D552 W556K511-V513 HydrophobicContact CD-CG2 4.18Å; K511-V513 HydrophobicContact CG-CG2 4.22Å; K511-C530 HydrophobicContact CG-CB 3.82Å; K511-C530 PolarHBondContact N-O 3.29Å; K511-C530 PolarHBondContact O-N 2.75Å; K511-D552 IonicContact NZ-OD2 3.45Å; K511-W556 HydrophobicContact CB-CH2 3.95Å; K511-W556 HydrophobicContact CB-CZ2 4.43Å; K511-W556 HydrophobicContact CB-CZ3 4.03Å; K511-W556 HydrophobicContact CD-CD2 3.73Å; K511-W556 HydrophobicContact CD-CE3 4Å; K511-W556 HydrophobicContact CD-CG 4.3Å; K511-W556 HydrophobicContact CD-CH2 4.04Å; K511-W556 HydrophobicContact CD-CZ2 3.75Å; K511-W556 HydrophobicContact CD-CZ3 4.16Å; K511-W556 VanDerWaalsContact CE-CG 3.45Å; K511-W556 HydrophobicContact CG-CD2 4.05Å; K511-W556 HydrophobicContact CG-CE3 3.77Å; K511-W556 HydrophobicContact CG-CH2 3.91Å; K511-W556 HydrophobicContact CG-CZ2 4.17Å; K511-W556 HydrophobicContact CG-CZ3 3.71Å; K511-W556 VanDerWaalsContact NZ-NE1 3.15Å
512L97.6Very high92.8Very high9 Ų927.6 Ų27.65%0.04715%0.145CC..EExtended strand (participates in β ladder)trans-107.2137169.2-58179.6000108.7A522 D525 E528 I529 W565 L571L512-A522 HydrophobicContact CB-CB 4.42Å; L512-A522 VanDerWaalsContact O-CB 3.26Å; L512-A522 WeakPolarHBondContact O-CB 3.43Å; L512-D525 VanDerWaalsContact CD1-C 3.48Å; L512-D525 WeakPolarHBondContact CD1-O 3.17Å; L512-E528 CarbonylContact C-O 3.58Å; L512-E528 VanDerWaalsContact CA-O 3.31Å; L512-E528 WeakPolarHBondContact CA-O 3.47Å; L512-I529 HydrophobicContact CD2-CB 4.47Å; L512-I529 HydrophobicContact CD2-CG1 3.88Å; L512-W565 VanDerWaalsContact CD1-CD1 3.43Å; L512-W565 HydrophobicContact CD1-CG 4.06Å; L512-L571 HydrophobicContact CD2-CD1 4.29Å
513V95.8Very high92.7Very high43 Ų4334 Ų3426%0.26118%0.175SC..EExtended strand (participates in β ladder)trans-117142.5178.11780000109.6K511 G527 E528 C530K511-V513 HydrophobicContact CD-CG2 4.18Å; K511-V513 HydrophobicContact CG-CG2 4.22Å; V513-G527 CarbonylContact O-C 3.55Å; V513-G527 VanDerWaalsContact O-CA 3.25Å; V513-G527 WeakPolarHBondContact O-CA 3.33Å; V513-E528 PolarHBondContact N-O 2.85Å; V513-E528 PolarHBondContact O-N 3.37Å; V513-C530 HydrophobicContact CG2-CB 4.34Å; V513-C530 VanDerWaalsContact CG2-SG 3.59Å
514D95Very high92.4Very high76 Ų7639 Ų3941%0.40620%0.201SC..  trans-54.3141.1179-61.9-13.4000111.9P516 F521 A522D514-P516 HydrophobicContact CB-CG 4.17Å; D514-F521 HydrophobicContact CB-CD1 4.39Å; D514-F521 WeakPolarHBondContact OD1-CA 3.41Å; D514-A522 WeakPolarHBondContact OD1-CB 3.35Å; D514-A522 PolarHBondContact OD1-N 3.36Å
515V90.5Very high92.3Very high0 Ų041.6 Ų41.60%022%0.215CC..BIsolated β-bridgetrans-126.174.9167.5-171.50000106.9E517 M518 N519 Y520 E528 I562 K577V515-E517 HydrophobicContact CG1-CG 3.91Å; V515-E517 WeakPolarHBondContact CG1-OE1 3.48Å; V515-E517 PolarHBondContact O-N 3.04Å; V515-M518 HydrophobicContact CG1-CB 3.95Å; V515-M518 HydrophobicContact CG1-CG 3.91Å; V515-M518 HydrophobicContact CG1-SD 3.9Å; V515-M518 CarbonylContact O-C 3.51Å; V515-M518 PolarHBondContact O-N 2.62Å; V515-N519 PolarHBondContact O-N 3.06Å; V515-Y520 CarbonylContact C-O 3.52Å; V515-Y520 PolarHBondContact N-O 3.42Å; V515-Y520 PolarHBondContact O-N 3.07Å; V515-E528 HydrophobicContact CG2-CB 3.72Å; V515-I562 HydrophobicContact CG2-CD1 3.79Å; V515-K577 HydrophobicContact CG1-CD 4.12Å; V515-K577 HydrophobicContact CG1-CG 4.25Å; V515-K577 HydrophobicContact CG2-CD 4.38Å
516P85.6Confident92.1Very high69 Ų6942.6 Ų42.645%0.44822%0.222SC..G310 helixtrans-59-32.8-172.7-23.434.1000112.4D514 M518 N519 F521D514-P516 HydrophobicContact CB-CG 4.17Å; P516-M518 PolarHBondContact O-N 2.95Å; P516-N519 PolarHBondContact O-N 3.24Å; P516-N519 VanDerWaalsContact O-N 3.12Å; P516-F521 HydrophobicContact CB-CE1 4.11Å; P516-F521 HydrophobicContact CG-CE1 4.34Å
517E79.2Confident92Very high94 Ų9442.6 Ų42.644%0.43922%0.222SC..G310 helixtrans-62.6-11.7175.865.1-89.7-155.300113.9V515 K577 Y588V515-E517 HydrophobicContact CG1-CG 3.91Å; V515-E517 WeakPolarHBondContact CG1-OE1 3.48Å; V515-E517 PolarHBondContact O-N 3.04Å; E517-K577 WeakPolarHBondContact OE1-CE 3.36Å; E517-K577 IonicContact OE1-NZ 3.07Å; E517-K577 PolarHBondContact OE1-NZ 3.49Å; E517-Y588 WeakPolarHBondContact O-CE1 3.29Å; E517-Y588 PolarHBondContact O-OH 2.9Å
518M76.7Confident92Very high21 Ų2143.3 Ų43.310%0.10323%0.225CC..G310 helixtrans-122.37.4177.1-65.6179.6-177.300113.3V515 P516 Y520 K577 I580 Y588V515-M518 HydrophobicContact CG1-CB 3.95Å; V515-M518 HydrophobicContact CG1-CG 3.91Å; V515-M518 HydrophobicContact CG1-SD 3.9Å; V515-M518 CarbonylContact O-C 3.51Å; V515-M518 PolarHBondContact O-N 2.62Å; P516-M518 PolarHBondContact O-N 2.95Å; M518-Y520 HydrophobicContact CB-CD2 3.63Å; M518-Y520 HydrophobicContact CB-CE2 4Å; M518-Y520 PolarHBondContact O-N 3.39Å; M518-K577 HydrophobicContact CE-CG 4.14Å; M518-K577 WeakPolarHBondContact CE-O 3.41Å; M518-K577 HydrophobicContact SD-CG 4.34Å; M518-I580 HydrophobicContact CE-CB 3.96Å; M518-I580 HydrophobicContact CE-CG2 4.26Å; M518-I580 HydrophobicContact CG-CG2 4.25Å; M518-I580 HydrophobicContact SD-CB 3.78Å; M518-I580 HydrophobicContact SD-CD1 3.77Å; M518-I580 HydrophobicContact SD-CG1 4.36Å; M518-I580 HydrophobicContact SD-CG2 3.85Å; M518-Y588 HydrophobicContact CB-CD1 4.32Å; M518-Y588 HydrophobicContact CB-CE1 4.47Å; M518-Y588 HydrophobicContact CG-CD1 4.1Å; M518-Y588 HydrophobicContact CG-CE1 4.14Å
519N82.5Confident92.1Very high106 Ų10643.3 Ų43.357%0.56723%0.225SC*.THydrogen-bonded Turntrans54.533.5-173.2-58.3-36.2000113.7V515 P516 F521V515-N519 PolarHBondContact O-N 3.06Å; P516-N519 PolarHBondContact O-N 3.24Å; P516-N519 VanDerWaalsContact O-N 3.12Å; N519-F521 HydrophobicContact CB-CE2 4.33Å
520Y89.5Confident92.1Very high48 Ų4842.7 Ų42.719%0.18822%0.222CC..BIsolated β-bridgetrans-100.7124.8166.5-67.4-64.3000109V515 M518 C526 I562 I574 I580V515-Y520 CarbonylContact C-O 3.52Å; V515-Y520 PolarHBondContact N-O 3.42Å; V515-Y520 PolarHBondContact O-N 3.07Å; M518-Y520 HydrophobicContact CB-CD2 3.63Å; M518-Y520 HydrophobicContact CB-CE2 4Å; M518-Y520 PolarHBondContact O-N 3.39Å; Y520-C526 CarbonylContact C-O 3.25Å; Y520-C526 HydrophobicContact CD1-CB 3.9Å; Y520-I562 HydrophobicContact CD1-CG2 4.46Å; Y520-I562 HydrophobicContact CD2-CG2 3.85Å; Y520-I562 HydrophobicContact CE1-CG2 4.5Å; Y520-I562 HydrophobicContact CE2-CG2 3.91Å; Y520-I562 HydrophobicContact CG-CG2 4.15Å; Y520-I574 HydrophobicContact CE1-CD1 3.92Å; Y520-I580 HydrophobicContact CE2-CD1 3.92Å
521F90.8Very high92.1Very high59 Ų5942.7 Ų42.726%0.25922%0.222SC..  trans-124.9131.9179-58.5-81.5000109.5D514 P516 N519 E523 D524 C526D514-F521 HydrophobicContact CB-CD1 4.39Å; D514-F521 WeakPolarHBondContact OD1-CA 3.41Å; P516-F521 HydrophobicContact CB-CE1 4.11Å; P516-F521 HydrophobicContact CG-CE1 4.34Å; N519-F521 HydrophobicContact CB-CE2 4.33Å; F521-E523 HydrophobicContact CB-CG 3.86Å; F521-E523 PolarHBondContact O-N 3.12Å; F521-D524 WeakPolarHBondContact O-CA 3.28Å; F521-D524 WeakPolarHBondContact O-CB 3.48Å; F521-D524 PolarHBondContact O-N 3.23Å; F521-C526 CarbonylContact C-O 3.42Å; F521-C526 PolarHBondContact N-O 3.11Å; F521-C526 PolarHBondContact O-N 2.79Å
522A92.7Very high92.1Very high13 Ų1345 Ų4511%0.10723%0.232CC..G310 helixtrans-57.1-24175.500000110.8R60 L512 D514 D524 D525 C526R60-A522 PolarHBondContact NE-O 3.11Å; R60-A522 VanDerWaalsContact NE-O 3.16Å; R60-A522 PolarHBondContact NH2-O 2.84Å; L512-A522 HydrophobicContact CB-CB 4.42Å; L512-A522 VanDerWaalsContact O-CB 3.26Å; L512-A522 WeakPolarHBondContact O-CB 3.43Å; D514-A522 WeakPolarHBondContact OD1-CB 3.35Å; D514-A522 PolarHBondContact OD1-N 3.36Å; A522-D524 VanDerWaalsContact C-N 3.27Å; A522-D524 PolarHBondContact O-N 3.26Å; A522-D525 PolarHBondContact O-N 3.09Å; A522-C526 PolarHBondContact N-O 3.19Å
523E92.2Very high92.1Very high135 Ų13545.5 Ų45.563%0.63124%0.239SC*.G310 helixtrans-60-37173.579-177.8161.800113.9R60 F521 D525R60-E523 VanDerWaalsContact NH1-CA 3.28Å; R60-E523 PolarHBondContact NH1-O 3.48Å; R60-E523 PolarHBondContact NH2-O 3.21Å; F521-E523 HydrophobicContact CB-CG 3.86Å; F521-E523 PolarHBondContact O-N 3.12Å; E523-D525 PolarHBondContact O-N 2.94Å
524D92.2Very high92.2Very high104 Ų10445.2 Ų45.256%0.55624%0.238SC*.G310 helixtrans-87.716.8175.4-59.6-43.5000112.4F521 A522 C526F521-D524 WeakPolarHBondContact O-CA 3.28Å; F521-D524 WeakPolarHBondContact O-CB 3.48Å; F521-D524 PolarHBondContact O-N 3.23Å; A522-D524 VanDerWaalsContact C-N 3.27Å; A522-D524 PolarHBondContact O-N 3.26Å; D524-C526 PolarHBondContact O-N 3.1Å
525D95Very high92.4Very high57 Ų5741.6 Ų41.631%0.30522%0.218SC..THydrogen-bonded Turntrans58.228.3-177.7-74.8-39.2000113.9R60 L512 A522 E523 C564 W565R60-D525 IonicContact CZ-OD1 2.74Å; R60-D525 IonicContact NE-OD1 2.89Å; R60-D525 IonicContact NH2-OD1 3.75Å; R60-D525 PolarHBondContact NH2-OD1 3.06Å; R60-D525 IonicContact NH2-OD2 3.84Å; L512-D525 VanDerWaalsContact CD1-C 3.48Å; L512-D525 WeakPolarHBondContact CD1-O 3.17Å; A522-D525 PolarHBondContact O-N 3.09Å; E523-D525 PolarHBondContact O-N 2.94Å; D525-C564 CarbonylContact O-C 3.44Å; D525-C564 WeakPolarHBondContact O-CA 3.29Å; D525-C564 VanDerWaalsContact O-CB 3.24Å; D525-C564 WeakPolarHBondContact O-CB 3.46Å; D525-W565 HydrophobicContact CB-CB 4.08Å; D525-W565 PolarHBondContact O-N 3.47Å
526C94.2Very high92.7Very high25 Ų2542.4 Ų42.417%0.16922%0.224CC..EExtended strand (participates in β ladder)trans-135.3135.7179.2-68.90000112Y520 F521 A522 D524 G563 C564Y520-C526 CarbonylContact C-O 3.25Å; Y520-C526 HydrophobicContact CD1-CB 3.9Å; F521-C526 CarbonylContact C-O 3.42Å; F521-C526 PolarHBondContact N-O 3.11Å; F521-C526 PolarHBondContact O-N 2.79Å; A522-C526 PolarHBondContact N-O 3.19Å; D524-C526 PolarHBondContact O-N 3.1Å; C526-G563 WeakPolarHBondContact CA-O 3.46Å; C526-C564 HydrophobicContact CB-CB 4.14Å; C526-C564 WeakPolarHBondContact CB-SG 3.34Å; C526-C564 WeakPolarHBondContact SG-CB 3.44Å; C526-C564 CovalentContact SG-SG 2.03Å; C526-C564 PolarHBondContact SG-SG 2.96Å
527G95.3Very high93.3Very high0 Ų039.4 Ų39.40%020%0.203CC..EExtended strand (participates in β ladder)trans176.2-170.7-179.400000114.1V513 I529 I562 G563V513-G527 CarbonylContact O-C 3.55Å; V513-G527 VanDerWaalsContact O-CA 3.25Å; V513-G527 WeakPolarHBondContact O-CA 3.33Å; G527-I529 PolarHBondContact O-N 3.19Å; G527-I562 WeakPolarHBondContact O-CA 3.41Å; G527-G563 PolarHBondContact N-O 3.16Å; G527-G563 PolarHBondContact O-N 2.84Å
528E96.7Very high94.1Very high16 Ų1641.3 Ų41.38%0.07521%0.21CC..EExtended strand (participates in β ladder)trans-65.6128.4168177.1171.7-142.700109.5L512 V513 V515 C530 H558 G560 D561 I562L512-E528 CarbonylContact C-O 3.58Å; L512-E528 VanDerWaalsContact CA-O 3.31Å; L512-E528 WeakPolarHBondContact CA-O 3.47Å; V513-E528 PolarHBondContact N-O 2.85Å; V513-E528 PolarHBondContact O-N 3.37Å; V515-E528 HydrophobicContact CG2-CB 3.72Å; E528-C530 PolarHBondContact O-N 3.27Å; E528-H558 IonicContact OE1-ND1 3.38Å; E528-H558 IonicContact OE2-CE1 2.67Å; E528-H558 IonicContact OE2-CG 3.27Å; E528-H558 IonicContact OE2-ND1 3.97Å; E528-H558 PolarHBondContact OE2-ND1 3.18Å; E528-G560 VanDerWaalsContact OE1-CA 3.29Å; E528-G560 WeakPolarHBondContact OE1-CA 3.43Å; E528-G560 PolarHBondContact OE1-N 3.13Å; E528-D561 WeakPolarHBondContact CA-O 3.32Å; E528-I562 HydrophobicContact CB-CD1 4.17Å
529I98Very high95Very high0 Ų040.3 Ų40.30%021%0.205CC..EExtended strand (participates in β ladder)trans-73.3123.6175.5-58.9162.9000107.5Y479 I510 L512 G527 L531 T559 D561 L571 L573Y479-I529 HydrophobicContact CE1-CD1 4.2Å; Y479-I529 HydrophobicContact CE1-CG2 4.13Å; I510-I529 HydrophobicContact CG2-CG2 3.86Å; L512-I529 HydrophobicContact CD2-CB 4.47Å; L512-I529 HydrophobicContact CD2-CG1 3.88Å; G527-I529 PolarHBondContact O-N 3.19Å; I529-L531 HydrophobicContact CG2-CD2 3.92Å; I529-T559 HydrophobicContact CB-CG2 4.36Å; I529-T559 HydrophobicContact CG2-CG2 4.15Å; I529-T559 WeakPolarHBondContact O-CB 3.42Å; I529-T559 WeakPolarHBondContact O-CG2 3.27Å; I529-T559 PolarHBondContact O-N 2.91Å; I529-T559 VanDerWaalsContact O-N 3.13Å; I529-T559 PolarHBondContact O-OG1 2.91Å; I529-D561 HydrophobicContact CD1-CB 4.16Å; I529-D561 PolarHBondContact N-O 3.32Å; I529-L571 HydrophobicContact CD1-CD1 4.23Å; I529-L571 HydrophobicContact CD1-CD2 3.96Å; I529-L571 HydrophobicContact CD1-CG 4.43Å; I529-L571 HydrophobicContact CG1-CD1 4.2Å; I529-L571 HydrophobicContact CG1-CD2 4.43Å; I529-L571 HydrophobicContact CG2-CD2 4.32Å; I529-L573 HydrophobicContact CD1-CD2 3.48Å; I529-L573 VanDerWaalsContact CD1-CD2 3.48Å
530C98.3Very high95.5Very high0 Ų035.7 Ų35.70%018%0.18CC..EExtended strand (participates in β ladder)trans-118.3136.5172.2-65.70000110.4I510 K511 V513 E528 W556 L557 H558I510-C530 WeakPolarHBondContact CA-O 3.19Å; K511-C530 HydrophobicContact CG-CB 3.82Å; K511-C530 PolarHBondContact N-O 3.29Å; K511-C530 PolarHBondContact O-N 2.75Å; V513-C530 HydrophobicContact CG2-CB 4.34Å; V513-C530 VanDerWaalsContact CG2-SG 3.59Å; E528-C530 PolarHBondContact O-N 3.27Å; C530-W556 HydrophobicContact CB-CB 4.24Å; C530-W556 HydrophobicContact CB-CE3 3.97Å; C530-W556 WeakPolarHBondContact O-CZ3 3.45Å; C530-L557 CarbonylContact C-O 3.56Å; C530-L557 WeakPolarHBondContact CA-O 3.28Å; C530-H558 PolarHBondContact SG-ND1 3.01Å; C530-H558 VanDerWaalsContact SG-ND1 3.45Å
531L98.5Very high95.6Very high0 Ų034.7 Ų34.70%018%0.176CC..EExtended strand (participates in β ladder)trans-112.8143-176.7-51.2179.1000110.6C484 A488 L509 I510 I529 V536 W556 L557 T559C484-L531 HydrophobicContact CB-CD1 3.78Å; A488-L531 HydrophobicContact CB-CD1 3.69Å; A488-L531 HydrophobicContact CB-CD2 3.87Å; A488-L531 HydrophobicContact CB-CG 4.46Å; L509-L531 WeakPolarHBondContact O-CA 3.26Å; I510-L531 HydrophobicContact CB-CD2 4.43Å; I510-L531 HydrophobicContact CD1-CD2 4.04Å; I510-L531 HydrophobicContact CG1-CD2 3.7Å; I510-L531 HydrophobicContact CG2-CD2 4.29Å; I529-L531 HydrophobicContact CG2-CD2 3.92Å; L531-V536 HydrophobicContact CB-CG2 4.38Å; L531-W556 VanDerWaalsContact C-CE3 3.48Å; L531-W556 CarbonylContact O-C 3.57Å; L531-W556 WeakPolarHBondContact O-CA 3.09Å; L531-L557 HydrophobicContact CB-CB 4.39Å; L531-L557 HydrophobicContact CD1-CD2 4.49Å; L531-L557 PolarHBondContact N-O 2.91Å; L531-L557 PolarHBondContact O-N 3.08Å; L531-T559 HydrophobicContact CD1-CG2 3.81Å; L531-T559 HydrophobicContact CD2-CG2 4.44Å; L531-T559 HydrophobicContact CG-CG2 3.68Å
532K98.1Very high95.4Very high71 Ų7133.5 Ų33.531%0.30917%0.171SC..EExtended strand (participates in β ladder)trans-145.3129.3171.3-179.6171.9177.2175.70109.6L509 D554 W556L509-K532 HydrophobicContact CB-CB 4.49Å; L509-K532 WeakPolarHBondContact CB-O 3.3Å; L509-K532 PolarHBondContact N-O 2.85Å; L509-K532 PolarHBondContact O-N 3.5Å; K532-D554 WeakPolarHBondContact CE-O 3.16Å; K532-D554 PolarHBondContact NZ-O 3.12Å; K532-W556 HydrophobicContact CB-CD2 3.63Å; K532-W556 HydrophobicContact CB-CE3 3.39Å; K532-W556 HydrophobicContact CB-CG 4.3Å; K532-W556 HydrophobicContact CB-CH2 3.99Å; K532-W556 HydrophobicContact CB-CZ2 4.21Å; K532-W556 HydrophobicContact CB-CZ3 3.58Å; K532-W556 HydrophobicContact CD-CD2 3.99Å; K532-W556 HydrophobicContact CD-CG 4.27Å; K532-W556 HydrophobicContact CD-CZ2 4.11Å; K532-W556 HydrophobicContact CG-CD2 4.46Å
533G97.9Very high95.3Very high19 Ų1935.5 Ų35.520%0.19618%0.178CC..SBendtrans169169.5-178.800000113.1A507 N535 V536A507-G533 WeakPolarHBondContact O-CA 3.17Å; G533-N535 PolarHBondContact O-N 2.87Å; G533-V536 WeakPolarHBondContact O-CB 3.29Å; G533-V536 PolarHBondContact O-N 2.89Å; G533-V536 VanDerWaalsContact O-N 3.09Å
534P97.8Very high95.2Very high36 Ų3633.8 Ų33.823%0.23418%0.179CC..THydrogen-bonded Turntrans-60.3-18.9178.227.4-41.1000114.5L74 N314 A317 A507L74-P534 HydrophobicContact CD2-CB 3.8Å; L74-P534 HydrophobicContact CD2-CG 3.77Å; N314-P534 VanDerWaalsContact CA-O 3.28Å; N314-P534 WeakPolarHBondContact CA-O 3.12Å; N314-P534 PolarHBondContact ND2-O 3.29Å; A317-P534 HydrophobicContact CB-CB 3.71Å; A317-P534 HydrophobicContact CB-CG 3.69Å; A507-P534 HydrophobicContact CB-CG 4.16Å; A507-P534 WeakPolarHBondContact O-CD 3.41Å
535N98.1Very high95.3Very high0 Ų036.2 Ų36.20%019%0.187CC..THydrogen-bonded Turntrans-84.8-9.6176.269.5-45.4000113.7N314 D318 C484 A507 N508 G533 F537N314-N535 WeakPolarHBondContact O-CA 3.26Å; D318-N535 HydrophobicContact CB-CB 3.83Å; C484-N535 CarbonylContact C-O 3.55Å; C484-N535 VanDerWaalsContact C-O 3.32Å; C484-N535 WeakPolarHBondContact CA-O 3.39Å; C484-N535 PolarHBondContact O-ND2 3.28Å; A507-N535 HydrophobicContact CB-CB 4.25Å; A507-N535 PolarHBondContact O-OD1 3.19Å; N508-N535 VanDerWaalsContact CG-OD1 3.24Å; N508-N535 VanDerWaalsContact ND2-CG 3.33Å; N508-N535 PolarHBondContact ND2-ND2 2.98Å; N508-N535 PolarHBondContact ND2-OD1 3.4Å; N508-N535 VanDerWaalsContact OD1-CG 3.29Å; N508-N535 PolarHBondContact OD1-ND2 3.49Å; N508-N535 PolarHBondContact OD1-OD1 3.31Å; G533-N535 PolarHBondContact O-N 2.87Å; N535-F537 PolarHBondContact O-N 3.02Å
536V98.4Very high95Very high18 Ų1836.5 Ų36.511%0.10919%0.185CC..SBendtrans-68.3131176.2176.10000109.4N314 L531 G533 L557N314-V536 PolarHBondContact ND2-O 3.41Å; L531-V536 HydrophobicContact CB-CG2 4.38Å; G533-V536 WeakPolarHBondContact O-CB 3.29Å; G533-V536 PolarHBondContact O-N 2.89Å; G533-V536 VanDerWaalsContact O-N 3.09Å; V536-L557 HydrophobicContact CG1-CB 3.92Å; V536-L557 HydrophobicContact CG1-CD2 4.12Å
537F98.1Very high95Very high5 Ų536.4 Ų36.42%0.02218%0.184CC..  trans-55.2159-179.678.4-36.4000113.7V308 M309 L310 E483 N535 G539 Y540 V550 I551 L557V308-F537 HydrophobicContact CB-CD2 4.27Å; V308-F537 HydrophobicContact CG1-CB 3.68Å; V308-F537 HydrophobicContact CG1-CD2 3.45Å; V308-F537 VanDerWaalsContact CG1-CD2 3.45Å; V308-F537 HydrophobicContact CG1-CE2 4.38Å; V308-F537 HydrophobicContact CG1-CG 3.91Å; M309-F537 WeakPolarHBondContact O-CB 3.36Å; L310-F537 HydrophobicContact CD2-CB 3.57Å; E483-F537 HydrophobicContact CB-CD1 3.96Å; E483-F537 HydrophobicContact CB-CD2 4.28Å; E483-F537 HydrophobicContact CB-CE1 4.05Å; E483-F537 HydrophobicContact CB-CE2 4.32Å; E483-F537 HydrophobicContact CB-CG 4.09Å; E483-F537 HydrophobicContact CB-CZ 4.22Å; E483-F537 HydrophobicContact CG-CD1 4.44Å; E483-F537 HydrophobicContact CG-CD2 4.04Å; E483-F537 HydrophobicContact CG-CE1 4.23Å; E483-F537 HydrophobicContact CG-CE2 3.75Å; E483-F537 HydrophobicContact CG-CG 4.36Å; E483-F537 HydrophobicContact CG-CZ 3.86Å; E483-F537 VanDerWaalsContact O-CB 3.31Å; E483-F537 WeakPolarHBondContact O-CB 3.46Å; E483-F537 VanDerWaalsContact O-CD1 3.26Å; E483-F537 WeakPolarHBondContact O-CD1 3.33Å; E483-F537 WeakPolarHBondContact O-CG 3.45Å; E483-F537 PolarHBondContact O-N 3.37Å; N535-F537 PolarHBondContact O-N 3.02Å; F537-G539 WeakPolarHBondContact CD2-O 3.5Å; F537-G539 VanDerWaalsContact CE2-CA 3.42Å; F537-G539 WeakPolarHBondContact CE2-O 3.34Å; F537-G539 PolarHBondContact O-N 3.29Å; F537-Y540 AromaticContact CE2-CD1 3.72Å; F537-Y540 HydrophobicContact CE2-CD1 3.72Å; F537-Y540 HydrophobicContact CE2-CD2 4.22Å; F537-Y540 AromaticContact CE2-CE1 3.71Å; F537-Y540 HydrophobicContact CE2-CE1 3.71Å; F537-Y540 HydrophobicContact CE2-CE2 4.23Å; F537-Y540 AromaticContact CE2-CG 3.99Å; F537-Y540 HydrophobicContact CE2-CG 3.99Å; F537-Y540 AromaticContact CE2-CZ 3.97Å; F537-Y540 HydrophobicContact CZ-CD2 4.42Å; F537-Y540 HydrophobicContact CZ-CE1 4.33Å; F537-Y540 HydrophobicContact CZ-CE2 4.19Å; F537-V550 HydrophobicContact CE1-CG2 4.42Å; F537-V550 HydrophobicContact CZ-CG2 3.87Å; F537-I551 HydrophobicContact CD1-CD1 4.21Å; F537-I551 HydrophobicContact CE1-CD1 3.61Å; F537-I551 HydrophobicContact CE1-CG1 3.88Å; F537-I551 HydrophobicContact CZ-CD1 4.26Å; F537-I551 HydrophobicContact CZ-CG1 4.44Å; F537-L557 HydrophobicContact CE1-CD1 3.88Å; F537-L557 HydrophobicContact CE1-CD2 4.4Å; F537-L557 HydrophobicContact CZ-CD1 4.45Å
538K95.6Very high95Very high134 Ų13440 Ų4058%0.58321%0.213SC*.SBendtrans-71.4-21.1176.5-170172.3-176.8171.30113.1L292 M309L292-K538 HydrophobicContact CD2-CD 4.31Å; M309-K538 HydrophobicContact CB-CB 4.19Å; M309-K538 PolarHBondContact O-N 2.63Å
539G95.7Very high94.8Very high0 Ų044.8 Ų44.80%024%0.235CC..EExtended strand (participates in β ladder)trans137.4-176.6-176.500000113M309 F537M309-G539 WeakPolarHBondContact CB-O 3.37Å; M309-G539 PolarHBondContact N-O 2.88Å; F537-G539 WeakPolarHBondContact CD2-O 3.5Å; F537-G539 VanDerWaalsContact CE2-CA 3.42Å; F537-G539 WeakPolarHBondContact CE2-O 3.34Å; F537-G539 PolarHBondContact O-N 3.29Å
540Y93Very high94.7Very high10 Ų1045.9 Ų45.94%0.03924%0.242CC..EExtended strand (participates in β ladder)trans-85.5131.7175.8-63.7-60.9000111.4K306 G307 V308 E483 F537 K542 E543 K546 T547 V550K306-Y540 HydrophobicContact CB-CD1 3.68Å; K306-Y540 HydrophobicContact CB-CE1 3.93Å; K306-Y540 HydrophobicContact CB-CG 4.26Å; K306-Y540 HydrophobicContact CD-CD1 4.32Å; K306-Y540 HydrophobicContact CD-CD2 4.38Å; K306-Y540 HydrophobicContact CD-CE1 4.15Å; K306-Y540 HydrophobicContact CD-CE2 4.19Å; K306-Y540 HydrophobicContact CD-CG 4.43Å; K306-Y540 PolarHBondContact NZ-OH 2.75Å; G307-Y540 CarbonylContact O-C 3.56Å; G307-Y540 VanDerWaalsContact O-CA 3.26Å; G307-Y540 WeakPolarHBondContact O-CA 3.33Å; V308-Y540 HydrophobicContact CG2-CD1 4.19Å; V308-Y540 HydrophobicContact CG2-CE1 3.92Å; E483-Y540 HydrophobicContact CG-CE1 3.96Å; E483-Y540 WeakPolarHBondContact OE1-CE1 2.74Å; E483-Y540 PolarHBondContact OE1-OH 3.24Å; F537-Y540 AromaticContact CE2-CD1 3.72Å; F537-Y540 HydrophobicContact CE2-CD1 3.72Å; F537-Y540 HydrophobicContact CE2-CD2 4.22Å; F537-Y540 AromaticContact CE2-CE1 3.71Å; F537-Y540 HydrophobicContact CE2-CE1 3.71Å; F537-Y540 HydrophobicContact CE2-CE2 4.23Å; F537-Y540 AromaticContact CE2-CG 3.99Å; F537-Y540 HydrophobicContact CE2-CG 3.99Å; F537-Y540 AromaticContact CE2-CZ 3.97Å; F537-Y540 HydrophobicContact CZ-CD2 4.42Å; F537-Y540 HydrophobicContact CZ-CE1 4.33Å; F537-Y540 HydrophobicContact CZ-CE2 4.19Å; Y540-K542 PolarHBondContact O-N 3.2Å; Y540-E543 PolarHBondContact O-N 3.03Å; Y540-E543 VanDerWaalsContact O-N 3.15Å; Y540-K546 HydrophobicContact CD2-CB 3.84Å; Y540-K546 HydrophobicContact CE2-CB 4.44Å; Y540-T547 PolarHBondContact N-OG1 2.69Å; Y540-V550 HydrophobicContact CD2-CG2 4.46Å; Y540-V550 HydrophobicContact CE2-CG1 4.32Å; Y540-V550 HydrophobicContact CE2-CG2 3.7Å
541Y90.5Very high94.7Very high27 Ų2747.8 Ų47.811%0.10625%0.252CS..THydrogen-bonded Turntrans-58.6119.8-178.9-169.8-105.2000110.5F144 A215 V295 G307 M309 E543F144-Y541 AromaticContact CE1-CE2 3.92Å; F144-Y541 HydrophobicContact CE1-CE2 3.92Å; F144-Y541 AromaticContact CZ-CE2 3.7Å; F144-Y541 HydrophobicContact CZ-CE2 3.7Å; F144-Y541 AromaticContact CZ-CZ 3.95Å; A215-Y541 HydrophobicContact CB-CE1 4.39Å; A215-Y541 WeakPolarHBondContact CB-OH 3.34Å; V295-Y541 HydrophobicContact CG1-CD2 4.47Å; V295-Y541 HydrophobicContact CG1-CG 4.11Å; V295-Y541 HydrophobicContact CG2-CD2 4.21Å; G307-Y541 WeakPolarHBondContact O-CB 3.4Å; G307-Y541 PolarHBondContact O-N 3.15Å; M309-Y541 HydrophobicContact CG-CD2 3.87Å; M309-Y541 HydrophobicContact CG-CG 4.45Å; M309-Y541 HydrophobicContact SD-CD2 3.69Å; M309-Y541 HydrophobicContact SD-CE2 4.48Å; Y541-E543 WeakPolarHBondContact O-CG 3.36Å; Y541-E543 PolarHBondContact O-N 3.3Å
542K87.5Confident94.5Very high34 Ų3449.8 Ų49.815%0.14826%0.263CS..THydrogen-bonded Turntrans59.822.5179.9-75.7-176.2-174.4173.30114.5Q197 L199 F213 Y540Q197-K542 PolarHBondContact O-NZ 3.49Å; L199-K542 HydrophobicContact CD1-CB 3.43Å; L199-K542 VanDerWaalsContact CD1-CB 3.43Å; L199-K542 HydrophobicContact CD1-CD 3.84Å; L199-K542 HydrophobicContact CD1-CG 3.62Å; L199-K542 HydrophobicContact CG-CB 3.8Å; L199-K542 HydrophobicContact CG-CD 3.95Å; L199-K542 HydrophobicContact CG-CG 4.18Å; F213-K542 PolarHBondContact O-NZ 3.38Å; Y540-K542 PolarHBondContact O-N 3.2Å
543E89.5Confident94.4Very high55 Ų5552.2 Ų52.226%0.25729%0.289SS..  trans-136.965.2-173.4-68-85.3-159.200110.8Y540 Y541 E545 K546 T547Y540-E543 PolarHBondContact O-N 3.03Å; Y540-E543 VanDerWaalsContact O-N 3.15Å; Y541-E543 WeakPolarHBondContact O-CG 3.36Å; Y541-E543 PolarHBondContact O-N 3.3Å; E543-E545 VanDerWaalsContact C-N 3.34Å; E543-E545 PolarHBondContact O-N 2.94Å; E543-K546 HydrophobicContact CB-CB 4.07Å; E543-K546 HydrophobicContact CB-CG 4.37Å; E543-K546 PolarHBondContact O-N 3.05Å; E543-T547 PolarHBondContact O-N 2.54Å; E543-T547 PolarHBondContact O-OG1 2.79Å
544P91.8Very high94.2Very high99 Ų9956 Ų5664%0.64330%0.304SS*.Hα-helixtrans-65.4-34.4-175.526.3-34.6000113T547 A548P544-T547 WeakPolarHBondContact O-CB 3.38Å; P544-T547 PolarHBondContact O-N 3.41Å; P544-A548 PolarHBondContact O-N 2.7Å
545E92.4Very high94.1Very high155 Ų15555.7 Ų55.772%0.72431%0.308SS*.Hα-helixtrans-64.1-48.1176.4-64.6-179.6-177.600110.8E543 T547 A548 E549E543-E545 VanDerWaalsContact C-N 3.34Å; E543-E545 PolarHBondContact O-N 2.94Å; E545-T547 PolarHBondContact O-N 3.46Å; E545-A548 PolarHBondContact O-N 2.82Å; E545-E549 WeakPolarHBondContact O-CG 3.07Å; E545-E549 PolarHBondContact O-N 2.76Å
546K90Very high94Very high63 Ų6355.7 Ų55.727%0.27431%0.308SS..Hα-helixtrans-63.7-27.8174.7-66.5-72.9166.8-143.10113Y540 E543 E549Y540-K546 HydrophobicContact CD2-CB 3.84Å; Y540-K546 HydrophobicContact CE2-CB 4.44Å; E543-K546 HydrophobicContact CB-CB 4.07Å; E543-K546 HydrophobicContact CB-CG 4.37Å; E543-K546 PolarHBondContact O-N 3.05Å; K546-E549 WeakPolarHBondContact CD-OE2 3.49Å; K546-E549 IonicContact NZ-OE1 2.72Å; K546-E549 PolarHBondContact NZ-OE1 3.46Å; K546-E549 IonicContact NZ-OE2 3.92Å; K546-E549 PolarHBondContact NZ-OE2 3.21Å
547T94.2Very high94Very high23 Ų2354.9 Ų54.914%0.14130%0.303CS..Hα-helixtrans-70-46.8174.4-57.20000110.4Y540 E543 P544 E545 E549 V550 I551Y540-T547 PolarHBondContact N-OG1 2.69Å; E543-T547 PolarHBondContact O-N 2.54Å; E543-T547 PolarHBondContact O-OG1 2.79Å; P544-T547 WeakPolarHBondContact O-CB 3.38Å; P544-T547 PolarHBondContact O-N 3.41Å; E545-T547 PolarHBondContact O-N 3.46Å; T547-E549 PolarHBondContact O-N 2.85Å; T547-V550 WeakPolarHBondContact O-CG2 3.18Å; T547-V550 PolarHBondContact O-N 3.43Å; T547-V550 VanDerWaalsContact O-N 3.12Å; T547-I551 HydrophobicContact CG2-CD1 4Å; T547-I551 HydrophobicContact CG2-CG1 4.48Å; T547-I551 PolarHBondContact O-N 3.19Å
548A95Very high94Very high74 Ų7456.9 Ų56.961%0.61231%0.312SS*.Hα-helixtrans-66.7-22.2176.500000113.5P544 E545 V550P544-A548 PolarHBondContact O-N 2.7Å; E545-A548 PolarHBondContact O-N 2.82Å; A548-V550 VanDerWaalsContact C-N 3.3Å
549E93.6Very high94Very high117 Ų11751.2 Ų51.255%0.54729%0.289SS..THydrogen-bonded Turntrans-68.4-25.2171.7-76.3175.2-155.500113.4E545 K546 T547E545-E549 WeakPolarHBondContact O-CG 3.07Å; E545-E549 PolarHBondContact O-N 2.76Å; K546-E549 WeakPolarHBondContact CD-OE2 3.49Å; K546-E549 IonicContact NZ-OE1 2.72Å; K546-E549 PolarHBondContact NZ-OE1 3.46Å; K546-E549 IonicContact NZ-OE2 3.92Å; K546-E549 PolarHBondContact NZ-OE2 3.21Å; T547-E549 PolarHBondContact O-N 2.85Å
550V95.2Very high93.8Very high24 Ų2452.3 Ų52.315%0.14530%0.3CS..THydrogen-bonded Turntrans-118.7-20.8-173-56.40000114.2F537 Y540 T547 A548 L557 H558F537-V550 HydrophobicContact CE1-CG2 4.42Å; F537-V550 HydrophobicContact CZ-CG2 3.87Å; Y540-V550 HydrophobicContact CD2-CG2 4.46Å; Y540-V550 HydrophobicContact CE2-CG1 4.32Å; Y540-V550 HydrophobicContact CE2-CG2 3.7Å; T547-V550 WeakPolarHBondContact O-CG2 3.18Å; T547-V550 PolarHBondContact O-N 3.43Å; T547-V550 VanDerWaalsContact O-N 3.12Å; A548-V550 VanDerWaalsContact C-N 3.3Å; V550-L557 HydrophobicContact CB-CD1 4.07Å; V550-L557 HydrophobicContact CG2-CD1 4.02Å; V550-L557 CarbonylContact O-C 3.55Å; V550-L557 WeakPolarHBondContact O-CA 3.49Å; V550-H558 PolarHBondContact O-N 3.06Å
551I97.1Very high93.7Very high40 Ų4052.6 Ų52.621%0.20530%0.302CS..BIsolated β-bridgetrans-105.8115.8172-55-178.1000108.2F537 T547 W556F537-I551 HydrophobicContact CD1-CD1 4.21Å; F537-I551 HydrophobicContact CE1-CD1 3.61Å; F537-I551 HydrophobicContact CE1-CG1 3.88Å; F537-I551 HydrophobicContact CZ-CD1 4.26Å; F537-I551 HydrophobicContact CZ-CG1 4.44Å; T547-I551 HydrophobicContact CG2-CD1 4Å; T547-I551 HydrophobicContact CG2-CG1 4.48Å; T547-I551 PolarHBondContact O-N 3.19Å; I551-W556 WeakPolarHBondContact CA-O 3.42Å
552D95.9Very high93.8Very high42 Ų4251.3 Ų51.323%0.22530%0.297CS..  trans-74.8173.8178.276.112.7000112.7K511 D554 G555 W556 H558K511-D552 IonicContact NZ-OD2 3.45Å; D552-D554 PolarHBondContact O-N 2.93Å; D552-D554 VanDerWaalsContact OD1-C 3.3Å; D552-D554 WeakPolarHBondContact OD1-CA 3.4Å; D552-D554 WeakPolarHBondContact OD1-CB 3.45Å; D552-D554 PolarHBondContact OD1-N 3.21Å; D552-G555 PolarHBondContact O-N 2.78Å; D552-G555 PolarHBondContact OD1-N 3Å; D552-W556 PolarHBondContact N-O 3.09Å; D552-W556 PolarHBondContact OD1-N 2.82Å; D552-W556 WeakPolarHBondContact OD2-CB 3.31Å; D552-H558 IonicContact OD2-NE2 2.96Å
553S94.5Very high94.1Very high122 Ų12249.7 Ų49.785%0.85329%0.29SS*.THydrogen-bonded Turntrans-63.9-20.1179.753.70000114.2G555S553-G555 VanDerWaalsContact C-N 3.34Å
554D94.2Very high94.4Very high97 Ų9748 Ų4852%0.51928%0.284SS..THydrogen-bonded Turntrans-91.6-0.2177.5-66.2-39.6000111.7K532 D552K532-D554 WeakPolarHBondContact CE-O 3.16Å; K532-D554 PolarHBondContact NZ-O 3.12Å; D552-D554 PolarHBondContact O-N 2.93Å; D552-D554 VanDerWaalsContact OD1-C 3.3Å; D552-D554 WeakPolarHBondContact OD1-CA 3.4Å; D552-D554 WeakPolarHBondContact OD1-CB 3.45Å; D552-D554 PolarHBondContact OD1-N 3.21Å
555G95.1Very high94.6Very high31 Ų3144 Ų4432%0.3226%0.256SS..SBendtrans83.217.9177.900000114.4D552 S553D552-G555 PolarHBondContact O-N 2.78Å; D552-G555 PolarHBondContact OD1-N 3Å; S553-G555 VanDerWaalsContact C-N 3.34Å
556W97.6Very high94.7Very high0 Ų037.7 Ų37.70%023%0.228CC..  trans-85.5129.9174.3-67.291.6000111.2E59 L509 K511 C530 L531 K532 I551 D552E59-W556 PolarHBondContact OE1-NE1 2.76Å; L509-W556 HydrophobicContact CB-CH2 3.69Å; L509-W556 HydrophobicContact CB-CZ3 4.03Å; L509-W556 HydrophobicContact CD1-CH2 4.44Å; K511-W556 HydrophobicContact CB-CH2 3.95Å; K511-W556 HydrophobicContact CB-CZ2 4.43Å; K511-W556 HydrophobicContact CB-CZ3 4.03Å; K511-W556 HydrophobicContact CD-CD2 3.73Å; K511-W556 HydrophobicContact CD-CE3 4Å; K511-W556 HydrophobicContact CD-CG 4.3Å; K511-W556 HydrophobicContact CD-CH2 4.04Å; K511-W556 HydrophobicContact CD-CZ2 3.75Å; K511-W556 HydrophobicContact CD-CZ3 4.16Å; K511-W556 VanDerWaalsContact CE-CG 3.45Å; K511-W556 HydrophobicContact CG-CD2 4.05Å; K511-W556 HydrophobicContact CG-CE3 3.77Å; K511-W556 HydrophobicContact CG-CH2 3.91Å; K511-W556 HydrophobicContact CG-CZ2 4.17Å; K511-W556 HydrophobicContact CG-CZ3 3.71Å; K511-W556 VanDerWaalsContact NZ-NE1 3.15Å; C530-W556 HydrophobicContact CB-CB 4.24Å; C530-W556 HydrophobicContact CB-CE3 3.97Å; C530-W556 WeakPolarHBondContact O-CZ3 3.45Å; L531-W556 VanDerWaalsContact C-CE3 3.48Å; L531-W556 CarbonylContact O-C 3.57Å; L531-W556 WeakPolarHBondContact O-CA 3.09Å; K532-W556 HydrophobicContact CB-CD2 3.63Å; K532-W556 HydrophobicContact CB-CE3 3.39Å; K532-W556 HydrophobicContact CB-CG 4.3Å; K532-W556 HydrophobicContact CB-CH2 3.99Å; K532-W556 HydrophobicContact CB-CZ2 4.21Å; K532-W556 HydrophobicContact CB-CZ3 3.58Å; K532-W556 HydrophobicContact CD-CD2 3.99Å; K532-W556 HydrophobicContact CD-CG 4.27Å; K532-W556 HydrophobicContact CD-CZ2 4.11Å; K532-W556 HydrophobicContact CG-CD2 4.46Å; I551-W556 WeakPolarHBondContact CA-O 3.42Å; D552-W556 PolarHBondContact N-O 3.09Å; D552-W556 PolarHBondContact OD1-N 2.82Å; D552-W556 WeakPolarHBondContact OD2-CB 3.31Å
557L98.3Very high94.9Very high1 Ų142.8 Ų42.81%0.00526%0.258CS..EExtended strand (participates in β ladder)trans-80.3113169169.959.1000110E483 C484 C530 L531 V536 F537 V550 T559E483-L557 HydrophobicContact CB-CD1 4.41Å; E483-L557 HydrophobicContact CB-CD2 3.65Å; C484-L557 HydrophobicContact CB-CD2 4.44Å; C530-L557 CarbonylContact C-O 3.56Å; C530-L557 WeakPolarHBondContact CA-O 3.28Å; L531-L557 HydrophobicContact CB-CB 4.39Å; L531-L557 HydrophobicContact CD1-CD2 4.49Å; L531-L557 PolarHBondContact N-O 2.91Å; L531-L557 PolarHBondContact O-N 3.08Å; V536-L557 HydrophobicContact CG1-CB 3.92Å; V536-L557 HydrophobicContact CG1-CD2 4.12Å; F537-L557 HydrophobicContact CE1-CD1 3.88Å; F537-L557 HydrophobicContact CE1-CD2 4.4Å; F537-L557 HydrophobicContact CZ-CD1 4.45Å; V550-L557 HydrophobicContact CB-CD1 4.07Å; V550-L557 HydrophobicContact CG2-CD1 4.02Å; V550-L557 CarbonylContact O-C 3.55Å; V550-L557 WeakPolarHBondContact O-CA 3.49Å; L557-T559 PolarHBondContact O-N 3.27Å
558H97.5Very high94.8Very high46 Ų4643.9 Ų43.921%0.21326%0.26CS..EExtended strand (participates in β ladder)trans-74.4110.2168.3-72.1-101.2000110.1E528 C530 V550 D552 G560E528-H558 IonicContact OE1-ND1 3.38Å; E528-H558 IonicContact OE2-CE1 2.67Å; E528-H558 IonicContact OE2-CG 3.27Å; E528-H558 IonicContact OE2-ND1 3.97Å; E528-H558 PolarHBondContact OE2-ND1 3.18Å; C530-H558 PolarHBondContact SG-ND1 3.01Å; C530-H558 VanDerWaalsContact SG-ND1 3.45Å; V550-H558 PolarHBondContact O-N 3.06Å; D552-H558 IonicContact OD2-NE2 2.96Å; H558-G560 VanDerWaalsContact C-N 3.33Å; H558-G560 PolarHBondContact O-N 2.75Å
559T95Very high94.8Very high16 Ų1640.5 Ų40.510%0.09823%0.232CC..EExtended strand (participates in β ladder)trans-74.8-22.8-175.265.80000113.3I529 L531 L557 D561I529-T559 HydrophobicContact CB-CG2 4.36Å; I529-T559 HydrophobicContact CG2-CG2 4.15Å; I529-T559 WeakPolarHBondContact O-CB 3.42Å; I529-T559 WeakPolarHBondContact O-CG2 3.27Å; I529-T559 PolarHBondContact O-N 2.91Å; I529-T559 VanDerWaalsContact O-N 3.13Å; I529-T559 PolarHBondContact O-OG1 2.91Å; L531-T559 HydrophobicContact CD1-CG2 3.81Å; L531-T559 HydrophobicContact CD2-CG2 4.44Å; L531-T559 HydrophobicContact CG-CG2 3.68Å; L557-T559 PolarHBondContact O-N 3.27Å; T559-D561 PolarHBondContact O-N 2.84Å; T559-D561 PolarHBondContact OG1-N 2.82Å; T559-D561 PolarHBondContact OG1-O 3.27Å
560G91.7Very high95Very high22 Ų2234.9 Ų34.923%0.22721%0.206CC..EExtended strand (participates in β ladder)trans69.12.7-166.800000114.4E528 H558 K577E528-G560 VanDerWaalsContact OE1-CA 3.29Å; E528-G560 WeakPolarHBondContact OE1-CA 3.43Å; E528-G560 PolarHBondContact OE1-N 3.13Å; H558-G560 VanDerWaalsContact C-N 3.33Å; H558-G560 PolarHBondContact O-N 2.75Å; G560-K577 WeakPolarHBondContact O-CB 3.45Å; G560-K577 PolarHBondContact O-N 3.07Å
561D91.6Very high95Very high17 Ų1733.8 Ų33.89%0.09120%0.199CC..EExtended strand (participates in β ladder)trans-94.2145.5171.1-59.8-48.2000109.5Y479 E528 I529 T559 R576Y479-D561 HydrophobicContact CE2-CB 4.5Å; Y479-D561 WeakPolarHBondContact CE2-OD2 3.48Å; Y479-D561 PolarHBondContact OH-OD2 2.68Å; E528-D561 WeakPolarHBondContact CA-O 3.32Å; I529-D561 HydrophobicContact CD1-CB 4.16Å; I529-D561 PolarHBondContact N-O 3.32Å; T559-D561 PolarHBondContact O-N 2.84Å; T559-D561 PolarHBondContact OG1-N 2.82Å; T559-D561 PolarHBondContact OG1-O 3.27Å; D561-R576 WeakPolarHBondContact OD1-CG 3.33Å; D561-R576 IonicContact OD1-CZ 3.15Å; D561-R576 IonicContact OD1-NE 2.73Å; D561-R576 PolarHBondContact OD1-NE 3.35Å; D561-R576 IonicContact OD1-NH2 2.77Å
562I92.4Very high94.8Very high0 Ų037.3 Ų37.30%021%0.21CC..EExtended strand (participates in β ladder)trans-104.2133.4178.4-55.8-56.4000108.8V515 Y520 G527 E528 I574 D575 K577 I580V515-I562 HydrophobicContact CG2-CD1 3.79Å; Y520-I562 HydrophobicContact CD1-CG2 4.46Å; Y520-I562 HydrophobicContact CD2-CG2 3.85Å; Y520-I562 HydrophobicContact CE1-CG2 4.5Å; Y520-I562 HydrophobicContact CE2-CG2 3.91Å; Y520-I562 HydrophobicContact CG-CG2 4.15Å; G527-I562 WeakPolarHBondContact O-CA 3.41Å; E528-I562 HydrophobicContact CB-CD1 4.17Å; I562-I574 HydrophobicContact CB-CB 4.45Å; I562-I574 HydrophobicContact CG2-CB 4.2Å; I562-I574 HydrophobicContact CG2-CD1 4.12Å; I562-I574 PolarHBondContact O-N 3.46Å; I562-D575 PolarHBondContact N-O 3Å; I562-K577 HydrophobicContact CD1-CB 3.93Å; I562-K577 HydrophobicContact CD1-CG 4.48Å; I562-K577 HydrophobicContact CG1-CB 4.32Å; I562-I580 HydrophobicContact CB-CD1 4.48Å; I562-I580 HydrophobicContact CG1-CD1 3.89Å
563G94.3Very high94.5Very high0 Ų038 Ų380%021%0.213CC..EExtended strand (participates in β ladder)trans-144.6170.9175.200000112.8C526 G527 R572C526-G563 WeakPolarHBondContact CA-O 3.46Å; G527-G563 PolarHBondContact N-O 3.16Å; G527-G563 PolarHBondContact O-N 2.84Å; G563-R572 CarbonylContact C-O 3.58Å; G563-R572 WeakPolarHBondContact CA-O 3.48Å
564C95.4Very high94Very high18 Ų1834 Ų3412%0.12218%0.182CC..EExtended strand (participates in β ladder)trans-129.1151170.4-56.10000111.3D525 C526 R572 I574D525-C564 CarbonylContact O-C 3.44Å; D525-C564 WeakPolarHBondContact O-CA 3.29Å; D525-C564 VanDerWaalsContact O-CB 3.24Å; D525-C564 WeakPolarHBondContact O-CB 3.46Å; C526-C564 HydrophobicContact CB-CB 4.14Å; C526-C564 WeakPolarHBondContact CB-SG 3.34Å; C526-C564 WeakPolarHBondContact SG-CB 3.44Å; C526-C564 CovalentContact SG-SG 2.03Å; C526-C564 PolarHBondContact SG-SG 2.96Å; C564-R572 PolarHBondContact N-O 3.38Å; C564-R572 PolarHBondContact O-N 2.91Å; C564-I574 WeakPolarHBondContact SG-CD1 3.49Å
565W96.4Very high93.2Very high17 Ų1729.9 Ų29.96%0.06416%0.16CC..EExtended strand (participates in β ladder)trans-74.2139163.1-61.9118.5000109.8R62 P504 I510 L512 D525 L571R62-W565 HydrophobicContact CB-CH2 3.92Å; R62-W565 HydrophobicContact CB-CZ2 3.9Å; R62-W565 VanDerWaalsContact CD-CD2 3.46Å; R62-W565 VanDerWaalsContact CD-CE2 3.48Å; R62-W565 HydrophobicContact CG-CH2 4.32Å; R62-W565 HydrophobicContact CG-CZ2 4Å; P504-W565 HydrophobicContact CG-CH2 4.22Å; I510-W565 HydrophobicContact CB-CH2 3.8Å; I510-W565 HydrophobicContact CB-CZ2 3.92Å; I510-W565 HydrophobicContact CG2-CH2 3.76Å; I510-W565 HydrophobicContact CG2-CZ2 3.68Å; L512-W565 VanDerWaalsContact CD1-CD1 3.43Å; L512-W565 HydrophobicContact CD1-CG 4.06Å; D525-W565 HydrophobicContact CB-CB 4.08Å; D525-W565 PolarHBondContact O-N 3.47Å; W565-L571 HydrophobicContact CE3-CB 4.3Å; W565-L571 HydrophobicContact CE3-CD1 4.45Å; W565-L571 HydrophobicContact CH2-CB 4.46Å; W565-L571 HydrophobicContact CZ3-CB 3.84Å; W565-L571 HydrophobicContact CZ3-CD1 4.35Å
566T94.8Very high92.3Very high22 Ų2231.3 Ų31.314%0.13516%0.156CC..  trans-87.3163.1164.974.80000109.8R568 G569 T570 R572T566-R568 PolarHBondContact O-N 3.13Å; T566-R568 PolarHBondContact OG1-N 3.41Å; T566-G569 PolarHBondContact O-N 3.12Å; T566-T570 WeakPolarHBondContact CG2-OG1 3.5Å; T566-T570 PolarHBondContact N-O 3.46Å; T566-T570 PolarHBondContact OG1-N 3.01Å; T566-T570 PolarHBondContact OG1-O 3.09Å; T566-T570 PolarHBondContact OG1-OG1 3.3Å; T566-R572 HydrophobicContact CG2-CB 4.21Å
567D92.6Very high91.3Very high169 Ų16934 Ų3490%0.90417%0.167SC*.THydrogen-bonded Turntrans-55.9-21.7171.4-56.5-27000112.5G569D567-G569 VanDerWaalsContact C-N 3.25Å; D567-G569 PolarHBondContact O-N 3.36Å
568R93.8Very high90.2Very high47 Ų4742.8 Ų42.818%0.17721%0.205CC..THydrogen-bonded Turntrans-82.31.5178-59.2174.761.7126.2-22.2113.8L48 D49 Q51 D495 T566 T570L48-R568 VanDerWaalsContact O-CZ 3.26Å; L48-R568 PolarHBondContact O-NE 3.15Å; L48-R568 PolarHBondContact O-NH2 3.39Å; D49-R568 HydrophobicContact CB-CG 4.49Å; D49-R568 VanDerWaalsContact O-CA 3.26Å; D49-R568 WeakPolarHBondContact O-CA 3.15Å; D49-R568 IonicContact OD1-CZ 2.76Å; D49-R568 VanDerWaalsContact OD1-CZ 3.24Å; D49-R568 IonicContact OD1-NE 3.43Å; D49-R568 PolarHBondContact OD1-NE 3.49Å; D49-R568 IonicContact OD1-NH1 2.86Å; D49-R568 PolarHBondContact OD1-NH1 3.17Å; Q51-R568 WeakPolarHBondContact CB-O 3.48Å; Q51-R568 PolarHBondContact N-O 2.8Å; D495-R568 IonicContact OD1-CZ 3.97Å; D495-R568 IonicContact OD1-NH2 3.93Å; D495-R568 PolarHBondContact OD1-NH2 3.2Å; T566-R568 PolarHBondContact O-N 3.13Å; T566-R568 PolarHBondContact OG1-N 3.41Å; R568-T570 VanDerWaalsContact C-N 3.29Å; R568-T570 HydrophobicContact CB-CG2 4.34Å; R568-T570 PolarHBondContact O-N 2.72Å
569G94.5Very high88.9Confident2 Ų242 Ų422%0.02120%0.202CC..SBendtrans68.626.3-174.200000113.7S52 T566 D567S52-G569 WeakPolarHBondContact CB-O 3.31Å; S52-G569 WeakPolarHBondContact OG-CA 3.1Å; S52-G569 PolarHBondContact OG-O 3.46Å; T566-G569 PolarHBondContact O-N 3.12Å; D567-G569 VanDerWaalsContact C-N 3.25Å; D567-G569 PolarHBondContact O-N 3.36Å
570T96.4Very high87.7Confident0 Ų041.9 Ų41.90%020%0.2CC..  trans-106154.8174.863.20000110.7Q51 Q500 T566 R568Q51-T570 HydrophobicContact CB-CG2 3.9Å; Q51-T570 HydrophobicContact CG-CG2 3.96Å; Q500-T570 VanDerWaalsContact CD-OG1 3.27Å; Q500-T570 PolarHBondContact OE1-OG1 3.18Å; T566-T570 WeakPolarHBondContact CG2-OG1 3.5Å; T566-T570 PolarHBondContact N-O 3.46Å; T566-T570 PolarHBondContact OG1-N 3.01Å; T566-T570 PolarHBondContact OG1-O 3.09Å; T566-T570 PolarHBondContact OG1-OG1 3.3Å; R568-T570 VanDerWaalsContact C-N 3.29Å; R568-T570 HydrophobicContact CB-CG2 4.34Å; R568-T570 PolarHBondContact O-N 2.72Å
571L96.8Very high86.8Confident0 Ų042.5 Ų42.50%020%0.197CC..EExtended strand (participates in β ladder)trans-86.2133.8176.4-175.965.8000110.4Y479 Q500 V501 G502 I510 L512 I529 W565 L573Y479-L571 HydrophobicContact CD1-CD2 3.98Å; Y479-L571 HydrophobicContact CE1-CD2 4.27Å; Q500-L571 CarbonylContact C-O 2.85Å; Q500-L571 WeakPolarHBondContact CA-O 3.42Å; V501-L571 HydrophobicContact CG2-CB 3.94Å; V501-L571 HydrophobicContact CG2-CD2 4.08Å; V501-L571 HydrophobicContact CG2-CG 4.03Å; V501-L571 VanDerWaalsContact CG2-O 3.27Å; V501-L571 WeakPolarHBondContact CG2-O 3.33Å; V501-L571 PolarHBondContact N-O 3.13Å; G502-L571 PolarHBondContact O-N 3.47Å; I510-L571 HydrophobicContact CD1-CD2 4.28Å; L512-L571 HydrophobicContact CD2-CD1 4.29Å; I529-L571 HydrophobicContact CD1-CD1 4.23Å; I529-L571 HydrophobicContact CD1-CD2 3.96Å; I529-L571 HydrophobicContact CD1-CG 4.43Å; I529-L571 HydrophobicContact CG1-CD1 4.2Å; I529-L571 HydrophobicContact CG1-CD2 4.43Å; I529-L571 HydrophobicContact CG2-CD2 4.32Å; W565-L571 HydrophobicContact CE3-CB 4.3Å; W565-L571 HydrophobicContact CE3-CD1 4.45Å; W565-L571 HydrophobicContact CH2-CB 4.46Å; W565-L571 HydrophobicContact CZ3-CB 3.84Å; W565-L571 HydrophobicContact CZ3-CD1 4.35Å; L571-L573 HydrophobicContact CD2-CD2 4.31Å
572R92.7Very high85.7Confident115 Ų11545.5 Ų45.543%0.43421%0.209SC..EExtended strand (participates in β ladder)trans-114.4126.6168.5173.3174-61168.910.4109.4G499 G563 C564 T566G499-R572 VanDerWaalsContact O-CG 3.29Å; G499-R572 WeakPolarHBondContact O-CG 3.43Å; G499-R572 PolarHBondContact O-NE 2.86Å; G563-R572 CarbonylContact C-O 3.58Å; G563-R572 WeakPolarHBondContact CA-O 3.48Å; C564-R572 PolarHBondContact N-O 3.38Å; C564-R572 PolarHBondContact O-N 2.91Å; T566-R572 HydrophobicContact CG2-CB 4.21Å
573L89.7Confident84.9Confident57 Ų5745.7 Ų45.730%0.29821%0.21SC..EExtended strand (participates in β ladder)trans-79.6138.3174.5-56.3179.3000110.5Y479 V501 I529 L571Y479-L573 HydrophobicContact CD1-CD2 4.16Å; Y479-L573 HydrophobicContact CD2-CD1 3.46Å; Y479-L573 VanDerWaalsContact CD2-CD1 3.46Å; Y479-L573 HydrophobicContact CD2-CD2 3.77Å; Y479-L573 HydrophobicContact CD2-CG 4.22Å; Y479-L573 HydrophobicContact CE1-CD2 4.3Å; Y479-L573 HydrophobicContact CE2-CD1 4.12Å; Y479-L573 HydrophobicContact CE2-CD2 3.9Å; Y479-L573 HydrophobicContact CG-CD1 3.96Å; Y479-L573 HydrophobicContact CG-CD2 3.9Å; Y479-L573 HydrophobicContact CG-CG 4.42Å; V501-L573 HydrophobicContact CG1-CD1 4.07Å; V501-L573 HydrophobicContact CG1-CG 4.22Å; V501-L573 HydrophobicContact CG2-CD2 4.26Å; V501-L573 HydrophobicContact CG2-CG 4.02Å; I529-L573 HydrophobicContact CD1-CD2 3.48Å; I529-L573 VanDerWaalsContact CD1-CD2 3.48Å; L571-L573 HydrophobicContact CD2-CD2 4.31Å
574I83.2Confident83.7Confident38 Ų3848.6 Ų48.620%0.19523%0.234CC..EExtended strand (participates in β ladder)trans-104.1-64.2174.8-64.9172.9000110.5Y520 I562 C564 A590Y520-I574 HydrophobicContact CE1-CD1 3.92Å; I562-I574 HydrophobicContact CB-CB 4.45Å; I562-I574 HydrophobicContact CG2-CB 4.2Å; I562-I574 HydrophobicContact CG2-CD1 4.12Å; I562-I574 PolarHBondContact O-N 3.46Å; C564-I574 WeakPolarHBondContact SG-CD1 3.49Å; I574-A590 HydrophobicContact CG2-CB 4.09Å
575D76.9Confident82.3Confident9 Ų951.8 Ų51.85%0.04825%0.247CC..EExtended strand (participates in β ladder)trans-170.1-164.9-175.4-148.5-53.7000109.6I562 I580 A590 P591 E592I562-D575 PolarHBondContact N-O 3Å; D575-I580 HydrophobicContact CB-CD1 4.01Å; D575-I580 HydrophobicContact CB-CG1 3.83Å; D575-A590 HydrophobicContact CB-CB 3.71Å; D575-A590 WeakPolarHBondContact OD2-CA 3.49Å; D575-A590 VanDerWaalsContact OD2-CB 3.24Å; D575-A590 WeakPolarHBondContact OD2-CB 3.48Å; D575-P591 VanDerWaalsContact OD2-CD 3.24Å; D575-P591 WeakPolarHBondContact OD2-CD 3.48Å; D575-P591 VanDerWaalsContact OD2-N 3.07Å; D575-E592 WeakPolarHBondContact OD2-CB 3.29Å; D575-E592 PolarHBondContact OD2-N 3.13Å
576R77.8Confident80.6Confident62 Ų6252.2 Ų52.223%0.23426%0.257CS..EExtended strand (participates in β ladder)trans-104136.9173.3-80.7174.5168.3-161-4.8112.1D561 K578 H579 I580D561-R576 WeakPolarHBondContact OD1-CG 3.33Å; D561-R576 IonicContact OD1-CZ 3.15Å; D561-R576 IonicContact OD1-NE 2.73Å; D561-R576 PolarHBondContact OD1-NE 3.35Å; D561-R576 IonicContact OD1-NH2 2.77Å; R576-K578 PolarHBondContact O-N 3.45Å; R576-K578 VanDerWaalsContact O-N 3.08Å; R576-H579 HydrophobicContact CB-CB 4.01Å; R576-H579 PolarHBondContact O-N 3.27Å; R576-I580 WeakPolarHBondContact O-CG1 3.49Å; R576-I580 PolarHBondContact O-N 2.78Å; R576-I580 VanDerWaalsContact O-N 3.13Å
577K74.8Confident79.4Confident56 Ų5655.3 Ų55.324%0.24327%0.27CS..THydrogen-bonded Turntrans-51.8-35.6174.9-175.3171.5177.2163.90112.3V515 E517 M518 G560 I562V515-K577 HydrophobicContact CG1-CD 4.12Å; V515-K577 HydrophobicContact CG1-CG 4.25Å; V515-K577 HydrophobicContact CG2-CD 4.38Å; E517-K577 WeakPolarHBondContact OE1-CE 3.36Å; E517-K577 IonicContact OE1-NZ 3.07Å; E517-K577 PolarHBondContact OE1-NZ 3.49Å; M518-K577 HydrophobicContact CE-CG 4.14Å; M518-K577 WeakPolarHBondContact CE-O 3.41Å; M518-K577 HydrophobicContact SD-CG 4.34Å; G560-K577 WeakPolarHBondContact O-CB 3.45Å; G560-K577 PolarHBondContact O-N 3.07Å; I562-K577 HydrophobicContact CD1-CB 3.93Å; I562-K577 HydrophobicContact CD1-CG 4.48Å; I562-K577 HydrophobicContact CG1-CB 4.32Å
578K75.1Confident78.5Confident186 Ų18649.9 Ų49.981%0.80924%0.237SC*.THydrogen-bonded Turntrans-82.9-13178.8-66.4-175.1179.2179.60114.7R576R576-K578 PolarHBondContact O-N 3.45Å; R576-K578 VanDerWaalsContact O-N 3.08Å
579H72.2Confident77.8Confident30 Ų3047.6 Ų47.614%0.13923%0.228CC..THydrogen-bonded Turntrans-103.2-23-175-67.5178.1000113.3R576 F581 E592R576-H579 HydrophobicContact CB-CB 4.01Å; R576-H579 PolarHBondContact O-N 3.27Å; H579-F581 WeakPolarHBondContact O-CD1 3.46Å; H579-E592 IonicContact CE1-OE1 3.68Å; H579-E592 PolarHBondContact CE1-OE1 3.26Å; H579-E592 IonicContact CG-OE1 3.34Å; H579-E592 IonicContact ND1-OE1 3.74Å; H579-E592 PolarHBondContact ND1-OE1 3.37Å
580I68Low77.1Confident13 Ų1347.8 Ų47.87%0.06723%0.23CC..  trans-65.5133.5173.7-63.6169.7000109.4M518 Y520 I562 D575 R576 Y588 I589 A590M518-I580 HydrophobicContact CE-CB 3.96Å; M518-I580 HydrophobicContact CE-CG2 4.26Å; M518-I580 HydrophobicContact CG-CG2 4.25Å; M518-I580 HydrophobicContact SD-CB 3.78Å; M518-I580 HydrophobicContact SD-CD1 3.77Å; M518-I580 HydrophobicContact SD-CG1 4.36Å; M518-I580 HydrophobicContact SD-CG2 3.85Å; Y520-I580 HydrophobicContact CE2-CD1 3.92Å; I562-I580 HydrophobicContact CB-CD1 4.48Å; I562-I580 HydrophobicContact CG1-CD1 3.89Å; D575-I580 HydrophobicContact CB-CD1 4.01Å; D575-I580 HydrophobicContact CB-CG1 3.83Å; R576-I580 WeakPolarHBondContact O-CG1 3.49Å; R576-I580 PolarHBondContact O-N 2.78Å; R576-I580 VanDerWaalsContact O-N 3.13Å; I580-Y588 HydrophobicContact CG2-CD1 4.05Å; I580-I589 WeakPolarHBondContact CA-O 3.34Å; I580-A590 HydrophobicContact CG1-CB 4.4Å
581F73.1Confident76.6Confident34 Ų3447.8 Ų47.815%0.14923%0.23CC..EExtended strand (participates in β ladder)trans-131.8158.5177.557.9-97.8000111.1H579 L583 Y588 I589 P591 G611 L618H579-F581 WeakPolarHBondContact O-CD1 3.46Å; F581-L583 HydrophobicContact CD2-CD2 4.45Å; F581-L583 HydrophobicContact CE2-CD2 4.05Å; F581-Y588 WeakPolarHBondContact O-CA 3.34Å; F581-I589 HydrophobicContact CD2-CB 4.15Å; F581-I589 HydrophobicContact CE1-CG2 4.35Å; F581-I589 HydrophobicContact CE2-CB 3.59Å; F581-I589 HydrophobicContact CE2-CG1 3.98Å; F581-I589 HydrophobicContact CE2-CG2 3.92Å; F581-I589 HydrophobicContact CZ-CB 3.82Å; F581-I589 HydrophobicContact CZ-CG2 3.64Å; F581-I589 PolarHBondContact N-O 3.44Å; F581-I589 PolarHBondContact O-N 2.96Å; F581-P591 HydrophobicContact CD1-CG 4.41Å; F581-P591 HydrophobicContact CE1-CB 3.96Å; F581-P591 HydrophobicContact CE1-CG 3.88Å; F581-G611 VanDerWaalsContact CZ-N 3.34Å; F581-L618 HydrophobicContact CE2-CD2 3.56Å; F581-L618 HydrophobicContact CZ-CD2 3.58Å
582K69.8Low75.8Confident81 Ų8150.4 Ų50.435%0.35224%0.242SC..EExtended strand (participates in β ladder)trans-98.7138.8179-165.7178.9-167.7151.30110.2G586 E587 Y588 D612 S613K582-G586 WeakPolarHBondContact CE-O 3.16Å; K582-E587 CarbonylContact C-O 3.53Å; K582-E587 WeakPolarHBondContact CA-O 3.3Å; K582-Y588 HydrophobicContact CB-CD1 4.1Å; K582-Y588 HydrophobicContact CB-CE1 3.89Å; K582-Y588 HydrophobicContact CD-CE1 4.17Å; K582-Y588 HydrophobicContact CD-CE2 4.06Å; K582-Y588 HydrophobicContact CG-CD1 4.45Å; K582-Y588 HydrophobicContact CG-CD2 4.48Å; K582-Y588 HydrophobicContact CG-CE1 4.15Å; K582-Y588 HydrophobicContact CG-CE2 4.17Å; K582-Y588 PolarHBondContact NZ-OH 2.89Å; K582-Y588 VanDerWaalsContact NZ-OH 3.11Å; K582-D612 CarbonylContact O-C 3.56Å; K582-S613 WeakPolarHBondContact O-CA 3.31Å; K582-S613 WeakPolarHBondContact O-CB 3.44Å; K582-S613 PolarHBondContact O-N 3.33Å; K582-S613 VanDerWaalsContact O-N 3.16Å; K582-S613 PolarHBondContact O-OG 2.92Å
583L73.8Confident75.1Confident3 Ų349.1 Ų49.12%0.01624%0.24CC..  trans-88.1168.4170.2-66.1178.2000111.6F581 Q585 G586 E587 I589 L618F581-L583 HydrophobicContact CD2-CD2 4.45Å; F581-L583 HydrophobicContact CE2-CD2 4.05Å; L583-Q585 HydrophobicContact CB-CG 4.47Å; L583-Q585 PolarHBondContact O-N 3.23Å; L583-G586 WeakPolarHBondContact O-CA 3.33Å; L583-G586 PolarHBondContact O-N 2.88Å; L583-E587 PolarHBondContact N-O 3.08Å; L583-I589 HydrophobicContact CD1-CD1 3.94Å; L583-I589 HydrophobicContact CD1-CG1 3.7Å; L583-I589 HydrophobicContact CG-CG1 3.79Å; L583-L618 HydrophobicContact CD1-CD2 4.42Å; L583-L618 HydrophobicContact CD1-CG 4.44Å; L583-L618 HydrophobicContact CD2-CD2 3.98Å
584A68.9Low74.9Confident61 Ų6146.4 Ų46.450%0.50423%0.225SC..THydrogen-bonded Turntrans-58.6-31.6-177.300000114.4G586 S613 K615A584-G586 PolarHBondContact O-N 3.35Å; A584-S613 WeakPolarHBondContact CA-O 3.1Å; A584-S613 WeakPolarHBondContact CB-O 3.1Å; A584-S613 PolarHBondContact N-O 2.94Å; A584-K615 WeakPolarHBondContact CB-O 3.37Å; A584-K615 PolarHBondContact N-O 2.84Å
585Q67.2Low75.2Confident86 Ų8645.3 Ų45.340%0.40222%0.219SC..THydrogen-bonded Turntrans-75-6.1174.862.3-922900113.9L583 E587 S616L583-Q585 HydrophobicContact CB-CG 4.47Å; L583-Q585 PolarHBondContact O-N 3.23Å; Q585-E587 HydrophobicContact CG-CB 4.08Å; Q585-E587 HydrophobicContact CG-CG 3.66Å; Q585-S616 PolarHBondContact NE2-O 2.83Å; Q585-S616 PolarHBondContact OE1-O 3.11Å
586G59.7Low75.4Confident26 Ų2647.7 Ų47.727%0.26823%0.232SC..SBendtrans94.5-1.8178.900000115.6K582 L583 A584K582-G586 WeakPolarHBondContact CE-O 3.16Å; L583-G586 WeakPolarHBondContact O-CA 3.33Å; L583-G586 PolarHBondContact O-N 2.88Å; A584-G586 PolarHBondContact O-N 3.35Å
587E71Confident75.6Confident86 Ų8645.8 Ų45.840%0.40223%0.227SC..  trans-73138.1176.1-63.1-60.5157.700111.5K582 L583 Q585 F672K582-E587 CarbonylContact C-O 3.53Å; K582-E587 WeakPolarHBondContact CA-O 3.3Å; L583-E587 PolarHBondContact N-O 3.08Å; Q585-E587 HydrophobicContact CG-CB 4.08Å; Q585-E587 HydrophobicContact CG-CG 3.66Å; E587-F672 HydrophobicContact CB-CD2 4.03Å; E587-F672 HydrophobicContact CB-CE2 4.06Å; E587-F672 HydrophobicContact CG-CD1 4.47Å; E587-F672 HydrophobicContact CG-CD2 4.16Å; E587-F672 HydrophobicContact CG-CE1 4.49Å; E587-F672 HydrophobicContact CG-CE2 4.19Å; E587-F672 HydrophobicContact CG-CG 4.31Å; E587-F672 HydrophobicContact CG-CZ 4.36Å
588Y73.2Confident76.4Confident55 Ų5543.1 Ų43.122%0.21622%0.215CC..EExtended strand (participates in β ladder)trans-92139.6174.9-70.2-95.1000110.6E517 M518 I580 F581 K582E517-Y588 WeakPolarHBondContact O-CE1 3.29Å; E517-Y588 PolarHBondContact O-OH 2.9Å; M518-Y588 HydrophobicContact CB-CD1 4.32Å; M518-Y588 HydrophobicContact CB-CE1 4.47Å; M518-Y588 HydrophobicContact CG-CD1 4.1Å; M518-Y588 HydrophobicContact CG-CE1 4.14Å; I580-Y588 HydrophobicContact CG2-CD1 4.05Å; F581-Y588 WeakPolarHBondContact O-CA 3.34Å; K582-Y588 HydrophobicContact CB-CD1 4.1Å; K582-Y588 HydrophobicContact CB-CE1 3.89Å; K582-Y588 HydrophobicContact CD-CE1 4.17Å; K582-Y588 HydrophobicContact CD-CE2 4.06Å; K582-Y588 HydrophobicContact CG-CD1 4.45Å; K582-Y588 HydrophobicContact CG-CD2 4.48Å; K582-Y588 HydrophobicContact CG-CE1 4.15Å; K582-Y588 HydrophobicContact CG-CE2 4.17Å; K582-Y588 PolarHBondContact NZ-OH 2.89Å; K582-Y588 VanDerWaalsContact NZ-OH 3.11Å
589I78.1Confident77Confident0 Ų037.7 Ų37.70%020%0.195CC..EExtended strand (participates in β ladder)trans-122125.3-177.1-58.7-63.8000109.2I580 F581 L583 P591 L594 L618 F672 E673I580-I589 WeakPolarHBondContact CA-O 3.34Å; F581-I589 HydrophobicContact CD2-CB 4.15Å; F581-I589 HydrophobicContact CE1-CG2 4.35Å; F581-I589 HydrophobicContact CE2-CB 3.59Å; F581-I589 HydrophobicContact CE2-CG1 3.98Å; F581-I589 HydrophobicContact CE2-CG2 3.92Å; F581-I589 HydrophobicContact CZ-CB 3.82Å; F581-I589 HydrophobicContact CZ-CG2 3.64Å; F581-I589 PolarHBondContact N-O 3.44Å; F581-I589 PolarHBondContact O-N 2.96Å; L583-I589 HydrophobicContact CD1-CD1 3.94Å; L583-I589 HydrophobicContact CD1-CG1 3.7Å; L583-I589 HydrophobicContact CG-CG1 3.79Å; I589-P591 WeakPolarHBondContact O-CD 3.4Å; I589-L594 HydrophobicContact CG2-CD1 3.62Å; I589-L618 HydrophobicContact CD1-CD1 4.28Å; I589-L618 HydrophobicContact CG1-CD1 4.43Å; I589-L618 HydrophobicContact CG1-CD2 4.23Å; I589-L618 HydrophobicContact CG2-CD1 3.94Å; I589-L618 HydrophobicContact CG2-CD2 4.08Å; I589-F672 HydrophobicContact CD1-CD2 3.84Å; I589-F672 HydrophobicContact CD1-CE2 4.18Å; I589-E673 HydrophobicContact CD1-CG 4.12Å
590A81.1Confident77.5Confident6 Ų640.1 Ų40.15%0.0521%0.206CC..  trans-9193.8166.600000109I574 D575 I580 E592 K593 L594I574-A590 HydrophobicContact CG2-CB 4.09Å; D575-A590 HydrophobicContact CB-CB 3.71Å; D575-A590 WeakPolarHBondContact OD2-CA 3.49Å; D575-A590 VanDerWaalsContact OD2-CB 3.24Å; D575-A590 WeakPolarHBondContact OD2-CB 3.48Å; I580-A590 HydrophobicContact CG1-CB 4.4Å; A590-E592 VanDerWaalsContact C-N 3.32Å; A590-E592 PolarHBondContact O-N 3.49Å; A590-K593 HydrophobicContact CB-CB 4.02Å; A590-K593 WeakPolarHBondContact O-CB 3.27Å; A590-K593 PolarHBondContact O-N 3.08Å; A590-L594 WeakPolarHBondContact O-CG 3.35Å
591P84.9Confident78.4Confident0 Ų039.7 Ų39.70%021%0.205CC..Hα-helixtrans-63.4-34.4-174.826.4-35.6000113.5D575 F581 I589 K593 L594 E595 V609 R700D575-P591 VanDerWaalsContact OD2-CD 3.24Å; D575-P591 WeakPolarHBondContact OD2-CD 3.48Å; D575-P591 VanDerWaalsContact OD2-N 3.07Å; F581-P591 HydrophobicContact CD1-CG 4.41Å; F581-P591 HydrophobicContact CE1-CB 3.96Å; F581-P591 HydrophobicContact CE1-CG 3.88Å; I589-P591 WeakPolarHBondContact O-CD 3.4Å; P591-K593 VanDerWaalsContact C-N 3.31Å; P591-K593 PolarHBondContact O-N 3.5Å; P591-L594 WeakPolarHBondContact O-CB 3.36Å; P591-L594 PolarHBondContact O-N 2.94Å; P591-L594 VanDerWaalsContact O-N 3.09Å; P591-E595 WeakPolarHBondContact O-CB 3.28Å; P591-E595 VanDerWaalsContact O-CG 3.24Å; P591-E595 WeakPolarHBondContact O-CG 3.43Å; P591-E595 PolarHBondContact O-N 3.46Å; P591-V609 HydrophobicContact CB-CB 4.38Å; P591-R700 VanDerWaalsContact CG-CZ 3.41Å; P591-R700 VanDerWaalsContact CG-NH2 3.25Å
592E80.2Confident78.9Confident55 Ų5543 Ų4326%0.25722%0.219SC..Hα-helixtrans-67.6-35.4-177.1-65.5-173.7-169.600110.9D575 H579 A590 L594 E595 N596D575-E592 WeakPolarHBondContact OD2-CB 3.29Å; D575-E592 PolarHBondContact OD2-N 3.13Å; H579-E592 IonicContact CE1-OE1 3.68Å; H579-E592 PolarHBondContact CE1-OE1 3.26Å; H579-E592 IonicContact CG-OE1 3.34Å; H579-E592 IonicContact ND1-OE1 3.74Å; H579-E592 PolarHBondContact ND1-OE1 3.37Å; A590-E592 VanDerWaalsContact C-N 3.32Å; A590-E592 PolarHBondContact O-N 3.49Å; E592-L594 VanDerWaalsContact C-N 3.3Å; E592-L594 PolarHBondContact O-N 2.98Å; E592-E595 PolarHBondContact O-N 2.69Å; E592-N596 WeakPolarHBondContact O-CB 3.15Å; E592-N596 VanDerWaalsContact O-CG 3.26Å; E592-N596 PolarHBondContact O-N 3.41Å; E592-N596 PolarHBondContact O-ND2 3.23Å; E592-N596 VanDerWaalsContact O-ND2 3.08Å
593K78.7Confident79.8Confident88 Ų8839.4 Ų39.438%0.38320%0.203SC..Hα-helixtrans-54.7-47169.5176.6-166.9170.5-164.30111.1A590 P591 V597 E673A590-K593 HydrophobicContact CB-CB 4.02Å; A590-K593 WeakPolarHBondContact O-CB 3.27Å; A590-K593 PolarHBondContact O-N 3.08Å; P591-K593 VanDerWaalsContact C-N 3.31Å; P591-K593 PolarHBondContact O-N 3.5Å; K593-V597 WeakPolarHBondContact O-CG2 3.16Å; K593-V597 PolarHBondContact O-N 3.26Å; K593-E673 IonicContact NZ-OE1 3.63Å; K593-E673 PolarHBondContact NZ-OE1 2.69Å; K593-E673 IonicContact NZ-OE2 3.11Å
594L85.3Confident80.6Confident0 Ų039.6 Ų39.60%020%0.204CC..Hα-helixtrans-70.6-45.1-178.1-50.7-178.9000111.5I589 A590 P591 E592 N596 V597 Y598 V609 L618 L669 E673I589-L594 HydrophobicContact CG2-CD1 3.62Å; A590-L594 WeakPolarHBondContact O-CG 3.35Å; P591-L594 WeakPolarHBondContact O-CB 3.36Å; P591-L594 PolarHBondContact O-N 2.94Å; P591-L594 VanDerWaalsContact O-N 3.09Å; E592-L594 VanDerWaalsContact C-N 3.3Å; E592-L594 PolarHBondContact O-N 2.98Å; L594-N596 VanDerWaalsContact C-N 3.32Å; L594-N596 PolarHBondContact O-N 2.77Å; L594-V597 WeakPolarHBondContact O-CB 3.28Å; L594-V597 PolarHBondContact O-N 3.12Å; L594-V597 VanDerWaalsContact O-N 3.11Å; L594-Y598 HydrophobicContact CB-CD2 4.31Å; L594-Y598 HydrophobicContact CB-CE2 3.8Å; L594-Y598 WeakPolarHBondContact O-CD2 3.33Å; L594-Y598 PolarHBondContact O-N 2.66Å; L594-V609 HydrophobicContact CB-CG2 4.44Å; L594-V609 HydrophobicContact CD1-CG1 4.19Å; L594-L618 HydrophobicContact CD1-CD1 3.42Å; L594-L618 VanDerWaalsContact CD1-CD1 3.42Å; L594-L669 HydrophobicContact CD2-CD1 3.77Å; L594-L669 HydrophobicContact CD2-CD2 3.59Å; L594-L669 HydrophobicContact CD2-CG 4.28Å; L594-E673 HydrophobicContact CD1-CB 4.47Å; L594-E673 WeakPolarHBondContact CD1-O 3.28Å; L594-E673 HydrophobicContact CD2-CB 3.81Å; L594-E673 HydrophobicContact CD2-CG 4.28Å
595E89.3Confident81.5Confident15 Ų1539.9 Ų39.97%0.0720%0.202CC..Hα-helixtrans-57.4-44.5177.7-71.2168.3-176.800111.1P591 E592 V597 Y598 L599 I607 V609 R700P591-E595 WeakPolarHBondContact O-CB 3.28Å; P591-E595 VanDerWaalsContact O-CG 3.24Å; P591-E595 WeakPolarHBondContact O-CG 3.43Å; P591-E595 PolarHBondContact O-N 3.46Å; E592-E595 PolarHBondContact O-N 2.69Å; E595-V597 VanDerWaalsContact C-N 3.32Å; E595-V597 PolarHBondContact O-N 3Å; E595-Y598 PolarHBondContact O-N 2.85Å; E595-L599 WeakPolarHBondContact O-CB 3.48Å; E595-L599 VanDerWaalsContact O-CG 3.29Å; E595-L599 WeakPolarHBondContact O-CG 3.44Å; E595-L599 PolarHBondContact O-N 3.42Å; E595-I607 HydrophobicContact CB-CG2 3.84Å; E595-I607 HydrophobicContact CG-CG2 3.98Å; E595-V609 HydrophobicContact CG-CB 3.94Å; E595-V609 HydrophobicContact CG-CG2 3.59Å; E595-V609 PolarHBondContact OE1-N 2.98Å; E595-R700 IonicContact OE1-CZ 3Å; E595-R700 IonicContact OE1-NH1 3.9Å; E595-R700 PolarHBondContact OE1-NH1 3.44Å; E595-R700 IonicContact OE1-NH2 2.76Å; E595-R700 IonicContact OE2-NH1 3.24Å; E595-R700 PolarHBondContact OE2-NH1 3.01Å
596N81Confident82.7Confident59 Ų5937.4 Ų37.432%0.31619%0.191SC..Hα-helixtrans-62.5-35.6176.1-74.6-33.7000112.8E592 L594 H600E592-N596 WeakPolarHBondContact O-CB 3.15Å; E592-N596 VanDerWaalsContact O-CG 3.26Å; E592-N596 PolarHBondContact O-N 3.41Å; E592-N596 PolarHBondContact O-ND2 3.23Å; E592-N596 VanDerWaalsContact O-ND2 3.08Å; L594-N596 VanDerWaalsContact C-N 3.32Å; L594-N596 PolarHBondContact O-N 2.77Å; N596-H600 PolarHBondContact O-CE1 3.09Å; N596-H600 PolarHBondContact O-ND1 2.81Å
597V82.7Confident84.3Confident21 Ų2136.5 Ų36.513%0.12718%0.18CC..Hα-helixtrans-64.6-49.6172170.60000110.3K593 L594 E595 L599 H600 L663 L669K593-V597 WeakPolarHBondContact O-CG2 3.16Å; K593-V597 PolarHBondContact O-N 3.26Å; L594-V597 WeakPolarHBondContact O-CB 3.28Å; L594-V597 PolarHBondContact O-N 3.12Å; L594-V597 VanDerWaalsContact O-N 3.11Å; E595-V597 VanDerWaalsContact C-N 3.32Å; E595-V597 PolarHBondContact O-N 3Å; V597-L599 VanDerWaalsContact C-N 3.34Å; V597-L599 PolarHBondContact O-N 3.09Å; V597-H600 WeakPolarHBondContact O-CB 3.32Å; V597-H600 PolarHBondContact O-N 3.34Å; V597-H600 PolarHBondContact O-ND1 2.78Å; V597-L663 HydrophobicContact CG1-CB 4.42Å; V597-L669 HydrophobicContact CB-CD1 4.4Å; V597-L669 HydrophobicContact CG1-CD1 4.14Å
598Y90.7Very high85.4Confident0 Ų032.5 Ų32.50%016%0.161CC..Hα-helixtrans-70.9-25.1-175.6-58.9-46.3000114.2L594 E595 H600 S601 I607 V609 M660 L669 E673 V675L594-Y598 HydrophobicContact CB-CD2 4.31Å; L594-Y598 HydrophobicContact CB-CE2 3.8Å; L594-Y598 WeakPolarHBondContact O-CD2 3.33Å; L594-Y598 PolarHBondContact O-N 2.66Å; E595-Y598 PolarHBondContact O-N 2.85Å; Y598-H600 PolarHBondContact O-N 3.5Å; Y598-H600 VanDerWaalsContact O-N 3.11Å; Y598-S601 WeakPolarHBondContact O-CB 3.49Å; Y598-S601 PolarHBondContact O-N 2.85Å; Y598-I607 HydrophobicContact CD2-CD1 3.69Å; Y598-I607 HydrophobicContact CG-CD1 3.99Å; Y598-V609 HydrophobicContact CD2-CG2 4.08Å; Y598-V609 HydrophobicContact CE2-CG2 4.12Å; Y598-M660 HydrophobicContact CD1-CB 3.8Å; Y598-M660 HydrophobicContact CD1-CE 3.95Å; Y598-M660 HydrophobicContact CD1-CG 4.01Å; Y598-M660 HydrophobicContact CD2-CE 3.77Å; Y598-M660 HydrophobicContact CE1-CB 3.97Å; Y598-M660 HydrophobicContact CE1-CE 4.19Å; Y598-M660 WeakPolarHBondContact CE1-O 2.78Å; Y598-M660 HydrophobicContact CE2-CE 4.02Å; Y598-M660 HydrophobicContact CG-CE 3.75Å; Y598-M660 HydrophobicContact CG-CG 4.38Å; Y598-L669 HydrophobicContact CE1-CD1 4.26Å; Y598-E673 PolarHBondContact OH-O 3.28Å; Y598-V675 HydrophobicContact CE2-CG2 3.76Å
599L87.8Confident86.4Confident72 Ų7229.9 Ų29.938%0.37715%0.151SC..THydrogen-bonded Turntrans-64-9.3173.1-77.2170.5000113.8E595 V597 I604 I607E595-L599 WeakPolarHBondContact O-CB 3.48Å; E595-L599 VanDerWaalsContact O-CG 3.29Å; E595-L599 WeakPolarHBondContact O-CG 3.44Å; E595-L599 PolarHBondContact O-N 3.42Å; V597-L599 VanDerWaalsContact C-N 3.34Å; V597-L599 PolarHBondContact O-N 3.09Å; L599-I604 HydrophobicContact CD2-CG2 4.29Å; L599-I607 HydrophobicContact CD2-CG2 4.03Å; L599-I607 HydrophobicContact CG-CG2 3.89Å
600H82.6Confident87.1Confident81 Ų8130.6 Ų30.638%0.37515%0.154SC..THydrogen-bonded Turntrans-76.8-11.9169.1-66.380.6000113.3S460 N596 V597 Y598 K602 L663S460-H600 VanDerWaalsContact CB-CE1 3.45Å; S460-H600 WeakPolarHBondContact CB-CE1 3.5Å; S460-H600 WeakPolarHBondContact CB-NE2 2.89Å; S460-H600 PolarHBondContact OG-NE2 2.85Å; S460-H600 VanDerWaalsContact OG-NE2 3.11Å; N596-H600 PolarHBondContact O-CE1 3.09Å; N596-H600 PolarHBondContact O-ND1 2.81Å; V597-H600 WeakPolarHBondContact O-CB 3.32Å; V597-H600 PolarHBondContact O-N 3.34Å; V597-H600 PolarHBondContact O-ND1 2.78Å; Y598-H600 PolarHBondContact O-N 3.5Å; Y598-H600 VanDerWaalsContact O-N 3.11Å; H600-K602 PolarHBondContact O-N 2.81Å; H600-L663 HydrophobicContact CB-CD1 4.41Å; H600-L663 HydrophobicContact CB-CD2 4.34Å
601S86.7Confident87.3Confident5 Ų530.6 Ų30.64%0.03516%0.155CC..  trans-65.4124.7174.6178.70000109.8Y598 F603 I604 D659Y598-S601 WeakPolarHBondContact O-CB 3.49Å; Y598-S601 PolarHBondContact O-N 2.85Å; S601-F603 PolarHBondContact O-N 3.16Å; S601-F603 PolarHBondContact OG-N 2.98Å; S601-I604 PolarHBondContact O-N 2.87Å; S601-D659 WeakPolarHBondContact CB-OD2 3.02Å; S601-D659 PolarHBondContact OG-OD2 2.95Å
602K84.2Confident87Confident104 Ų10432.7 Ų32.745%0.45217%0.166SC..THydrogen-bonded Turntrans-58.2-17.4171.565.7-171178.9-172.20113.3H600 F628H600-K602 PolarHBondContact O-N 2.81Å; K602-F628 WeakPolarHBondContact O-CB 3.22Å
603F89.2Confident86.4Confident4 Ų433 Ų332%0.01818%0.175CC..THydrogen-bonded Turntrans-92.1-11.2-179.5-55.1-60.6000113.4S601 P624 N625 L629 H632 L655 I656 D659S601-F603 PolarHBondContact O-N 3.16Å; S601-F603 PolarHBondContact OG-N 2.98Å; F603-P624 CarbonylContact O-C 3.43Å; F603-P624 VanDerWaalsContact O-CA 3.29Å; F603-P624 WeakPolarHBondContact O-CA 3.38Å; F603-N625 PolarHBondContact O-N 2.82Å; F603-L629 HydrophobicContact CD1-CB 4.49Å; F603-L629 HydrophobicContact CD1-CD1 3.9Å; F603-L629 HydrophobicContact CE1-CD1 4.43Å; F603-H632 HydrophobicContact CE1-CB 3.82Å; F603-H632 AromaticContact CE1-CD2 3.77Å; F603-H632 AromaticContact CE1-CG 3.7Å; F603-H632 AromaticContact CZ-CD2 3.72Å; F603-H632 AromaticContact CZ-CG 3.91Å; F603-H632 AromaticContact CZ-NE2 3.89Å; F603-L655 HydrophobicContact CE1-CD2 4.34Å; F603-L655 HydrophobicContact CE2-CD1 4.39Å; F603-L655 HydrophobicContact CE2-CG 4.33Å; F603-L655 HydrophobicContact CZ-CD1 4.31Å; F603-L655 HydrophobicContact CZ-CD2 4.19Å; F603-L655 HydrophobicContact CZ-CG 4.33Å; F603-I656 HydrophobicContact CB-CG1 4.19Å; F603-D659 HydrophobicContact CD2-CB 4.04Å; F603-D659 HydrophobicContact CE2-CB 4.12Å
604I90.8Very high86.1Confident7 Ų736 Ų364%0.03619%0.194CC..EExtended strand (participates in β ladder)trans-112.6127.4-171.7-60.1-177000109.4L599 S601 Q606 I607 V622 I656 M660L599-I604 HydrophobicContact CD2-CG2 4.29Å; S601-I604 PolarHBondContact O-N 2.87Å; I604-Q606 WeakPolarHBondContact CG2-O 3.42Å; I604-I607 HydrophobicContact CD1-CD1 4.48Å; I604-I607 HydrophobicContact CG2-CB 4.09Å; I604-V622 HydrophobicContact CB-CG1 4.34Å; I604-V622 HydrophobicContact CD1-CG1 4.1Å; I604-V622 HydrophobicContact CD1-CG2 4.35Å; I604-V622 HydrophobicContact CG1-CG1 3.72Å; I604-V622 HydrophobicContact CG2-CG1 4.1Å; I604-I656 HydrophobicContact CD1-CG2 4.15Å; I604-I656 HydrophobicContact CG1-CG2 4.18Å; I604-M660 HydrophobicContact CD1-CG 3.68Å; I604-M660 HydrophobicContact CD1-SD 3.77Å
605S87.7Confident85.7Confident67 Ų6739.5 Ų39.547%0.46921%0.209SC..EExtended strand (participates in β ladder)trans-97.6-37.5171.2-177.30000112.3V623S605-V623 PolarHBondContact N-O 3.39Å
606Q91.7Very high85.2Confident35 Ų3542.6 Ų42.616%0.16423%0.232CC..EExtended strand (participates in β ladder)trans-146.1152.2176.9-54.1172.2-62.400108.8I604 V623 F685I604-Q606 WeakPolarHBondContact CG2-O 3.42Å; Q606-V623 HydrophobicContact CB-CB 3.9Å; Q606-V623 HydrophobicContact CB-CG2 3.97Å; Q606-V623 HydrophobicContact CG-CB 4.45Å; Q606-V623 PolarHBondContact N-O 3.3Å; Q606-V623 PolarHBondContact O-N 3.46Å; Q606-F685 HydrophobicContact CB-CD2 3.9Å; Q606-F685 HydrophobicContact CB-CE2 4.1Å; Q606-F685 PolarHBondContact NE2-O 2.9Å
607I94.5Very high85.5Confident7 Ų740.7 Ų40.74%0.03622%0.223CC..EExtended strand (participates in β ladder)trans-144.7147179.4-174.1168.3000110.5E595 Y598 L599 I604 V609 A620 V621 V622 M660E595-I607 HydrophobicContact CB-CG2 3.84Å; E595-I607 HydrophobicContact CG-CG2 3.98Å; Y598-I607 HydrophobicContact CD2-CD1 3.69Å; Y598-I607 HydrophobicContact CG-CD1 3.99Å; L599-I607 HydrophobicContact CD2-CG2 4.03Å; L599-I607 HydrophobicContact CG-CG2 3.89Å; I604-I607 HydrophobicContact CD1-CD1 4.48Å; I604-I607 HydrophobicContact CG2-CB 4.09Å; I607-V609 HydrophobicContact CD1-CG2 4.11Å; I607-V609 HydrophobicContact CG1-CG2 4.24Å; I607-A620 HydrophobicContact CD1-CB 4.08Å; I607-A620 HydrophobicContact CG1-CB 4.11Å; I607-V621 CarbonylContact C-O 3.6Å; I607-V621 WeakPolarHBondContact CA-O 3.35Å; I607-V622 HydrophobicContact CD1-CG2 4.19Å; I607-V622 HydrophobicContact CG1-CG2 4.21Å; I607-M660 HydrophobicContact CD1-CE 3.62Å; I607-M660 HydrophobicContact CD1-SD 4.47Å
608F94.3Very high86Confident2 Ų239.7 Ų39.71%0.00922%0.217CC..EExtended strand (participates in β ladder)trans-131.1109.7169.8168.1-119.1000108.7H610 A620 V621 F685 R700 L703 R704 I711F608-H610 HydrophobicContact CE1-CB 3.99Å; F608-H610 HydrophobicContact CZ-CB 4.13Å; F608-A620 CarbonylContact O-C 3.59Å; F608-A620 WeakPolarHBondContact O-CA 3.44Å; F608-A620 WeakPolarHBondContact O-CB 3.2Å; F608-V621 HydrophobicContact CB-CB 4.38Å; F608-V621 HydrophobicContact CD1-CB 4.43Å; F608-V621 HydrophobicContact CD1-CG2 4.29Å; F608-V621 PolarHBondContact N-O 2.86Å; F608-V621 PolarHBondContact O-N 3.07Å; F608-F685 HydrophobicContact CB-CE2 3.96Å; F608-F685 HydrophobicContact CB-CZ 4.06Å; F608-R700 HydrophobicContact CE2-CB 3.99Å; F608-R700 HydrophobicContact CE2-CG 4.22Å; F608-L703 HydrophobicContact CB-CD1 4.28Å; F608-L703 HydrophobicContact CD1-CB 3.95Å; F608-L703 HydrophobicContact CD2-CB 4.27Å; F608-L703 HydrophobicContact CD2-CD1 3.97Å; F608-L703 HydrophobicContact CE1-CB 3.9Å; F608-L703 HydrophobicContact CE2-CB 4.23Å; F608-L703 HydrophobicContact CG-CB 4.13Å; F608-L703 HydrophobicContact CG-CD1 4.07Å; F608-L703 HydrophobicContact CZ-CB 4.04Å; F608-R704 HydrophobicContact CZ-CB 4.32Å; F608-I711 HydrophobicContact CE1-CD1 4.21Å
609V94Very high86.2Confident0 Ų039.7 Ų39.70%022%0.217CC..EExtended strand (participates in β ladder)trans-87.8132.1176.1175.20000108.8P591 L594 E595 Y598 I607 L618 A620 V675 R700P591-V609 HydrophobicContact CB-CB 4.38Å; L594-V609 HydrophobicContact CB-CG2 4.44Å; L594-V609 HydrophobicContact CD1-CG1 4.19Å; E595-V609 HydrophobicContact CG-CB 3.94Å; E595-V609 HydrophobicContact CG-CG2 3.59Å; E595-V609 PolarHBondContact OE1-N 2.98Å; Y598-V609 HydrophobicContact CD2-CG2 4.08Å; Y598-V609 HydrophobicContact CE2-CG2 4.12Å; I607-V609 HydrophobicContact CD1-CG2 4.11Å; I607-V609 HydrophobicContact CG1-CG2 4.24Å; V609-L618 HydrophobicContact CG1-CB 4.37Å; V609-L618 HydrophobicContact CG1-CD1 4.27Å; V609-L618 HydrophobicContact CG1-CD2 4.39Å; V609-A620 HydrophobicContact CG2-CB 4.12Å; V609-V675 HydrophobicContact CG1-CG2 4.2Å; V609-V675 HydrophobicContact CG2-CG2 4.1Å; V609-R700 PolarHBondContact O-NH2 3.5Å
610H92.2Very high86.7Confident15 Ų1536.3 Ų36.37%0.06920%0.2CC..EExtended strand (participates in β ladder)trans-125.8143.3-179.9-17766.7000111.6F608 L618 V619 I711 Y715F608-H610 HydrophobicContact CE1-CB 3.99Å; F608-H610 HydrophobicContact CZ-CB 4.13Å; H610-L618 WeakPolarHBondContact O-CA 3.5Å; H610-V619 HydrophobicContact CB-CG2 4.18Å; H610-V619 PolarHBondContact N-O 2.63Å; H610-V619 PolarHBondContact O-N 3.2Å; H610-I711 HydrophobicContact CB-CD1 4.41Å; H610-I711 VanDerWaalsContact CD2-CG2 3.47Å; H610-I711 WeakPolarHBondContact CD2-CG2 3.36Å; H610-Y715 AromaticContact CD2-CE2 4Å; H610-Y715 PolarHBondContact O-OH 2.97Å
611G85.7Confident87.4Confident6 Ų632.5 Ų32.56%0.06218%0.182CC..  trans-148.2162.5167.900000111F581 Y715F581-G611 VanDerWaalsContact CZ-N 3.34Å; G611-Y715 WeakPolarHBondContact CA-OH 3.24Å
612D76.9Confident87.9Confident43 Ų4332.3 Ų32.323%0.2318%0.181CC..  trans-139.9150.4177.9-167.8-48.4000108.4K582 L614 K615 R704K582-D612 CarbonylContact O-C 3.56Å; D612-L614 PolarHBondContact O-N 3.27Å; D612-L614 PolarHBondContact OD1-N 3.01Å; D612-L614 VanDerWaalsContact OD1-N 3.08Å; D612-K615 HydrophobicContact CB-CG 4.17Å; D612-K615 PolarHBondContact O-N 3.19Å; D612-R704 IonicContact OD2-CZ 3.83Å; D612-R704 IonicContact OD2-NH2 3.24Å; D612-R704 PolarHBondContact OD2-NH2 3.46Å
613S69Low88.3Confident63 Ų6327.8 Ų27.844%0.44116%0.162SC..THydrogen-bonded Turntrans-63.7-15.4177.5-52.70000114.3K582 A584K582-S613 WeakPolarHBondContact O-CA 3.31Å; K582-S613 WeakPolarHBondContact O-CB 3.44Å; K582-S613 PolarHBondContact O-N 3.33Å; K582-S613 VanDerWaalsContact O-N 3.16Å; K582-S613 PolarHBondContact O-OG 2.92Å; A584-S613 WeakPolarHBondContact CA-O 3.1Å; A584-S613 WeakPolarHBondContact CB-O 3.1Å; A584-S613 PolarHBondContact N-O 2.94Å
614L71.1Confident88.5Confident149 Ų14928.1 Ų28.178%0.7817%0.165SC*.THydrogen-bonded Turntrans-89.3-2.7171.8-60.1179.7000113.8D612D612-L614 PolarHBondContact O-N 3.27Å; D612-L614 PolarHBondContact OD1-N 3.01Å; D612-L614 VanDerWaalsContact OD1-N 3.08Å
615K78.3Confident88.4Confident75 Ų7529.5 Ų29.533%0.32617%0.172SC..  trans-117.2142.6-174.9-58.8-63.9-173.4179.90110.5A584 D612 Y715A584-K615 WeakPolarHBondContact CB-O 3.37Å; A584-K615 PolarHBondContact N-O 2.84Å; D612-K615 HydrophobicContact CB-CG 4.17Å; D612-K615 PolarHBondContact O-N 3.19Å; K615-Y715 HydrophobicContact CB-CD1 4.14Å; K615-Y715 HydrophobicContact CB-CE1 3.57Å; K615-Y715 HydrophobicContact CD-CD1 3.62Å; K615-Y715 HydrophobicContact CD-CD2 4.19Å; K615-Y715 HydrophobicContact CD-CE1 3.95Å; K615-Y715 HydrophobicContact CD-CE2 4.46Å; K615-Y715 HydrophobicContact CD-CG 3.77Å; K615-Y715 HydrophobicContact CG-CD1 3.81Å; K615-Y715 HydrophobicContact CG-CD2 4.09Å; K615-Y715 HydrophobicContact CG-CE1 3.59Å; K615-Y715 HydrophobicContact CG-CE2 3.86Å; K615-Y715 HydrophobicContact CG-CG 4.07Å
616S78.4Confident88.3Confident80 Ų8030.6 Ų30.656%0.55917%0.171SC*.SBendtrans-87.2-8.6-178.656.30000114Q585Q585-S616 PolarHBondContact NE2-O 2.83Å; Q585-S616 PolarHBondContact OE1-O 3.11Å
617C87Confident87.9Confident19 Ų1935.3 Ų35.313%0.12819%0.193CC..SBendtrans-142.9164.6-171.657.90000112.6K676 Y715C617-K676 HydrophobicContact CB-CB 4.27Å; C617-K676 HydrophobicContact CB-CG 3.59Å; C617-Y715 WeakPolarHBondContact O-CE1 3.42Å; C617-Y715 PolarHBondContact O-OH 2.63Å; C617-Y715 VanDerWaalsContact O-OH 3.13Å
618L93.2Very high87.3Confident0 Ų037.2 Ų37.20%020%0.201CC..EExtended strand (participates in β ladder)trans-97146.1179.6-61.3174.1000111.1F581 L583 I589 L594 V609 H610 E673 V675 K676F581-L618 HydrophobicContact CE2-CD2 3.56Å; F581-L618 HydrophobicContact CZ-CD2 3.58Å; L583-L618 HydrophobicContact CD1-CD2 4.42Å; L583-L618 HydrophobicContact CD1-CG 4.44Å; L583-L618 HydrophobicContact CD2-CD2 3.98Å; I589-L618 HydrophobicContact CD1-CD1 4.28Å; I589-L618 HydrophobicContact CG1-CD1 4.43Å; I589-L618 HydrophobicContact CG1-CD2 4.23Å; I589-L618 HydrophobicContact CG2-CD1 3.94Å; I589-L618 HydrophobicContact CG2-CD2 4.08Å; L594-L618 HydrophobicContact CD1-CD1 3.42Å; L594-L618 VanDerWaalsContact CD1-CD1 3.42Å; V609-L618 HydrophobicContact CG1-CB 4.37Å; V609-L618 HydrophobicContact CG1-CD1 4.27Å; V609-L618 HydrophobicContact CG1-CD2 4.39Å; H610-L618 WeakPolarHBondContact O-CA 3.5Å; L618-E673 WeakPolarHBondContact CD1-O 3.49Å; L618-V675 HydrophobicContact CB-CG2 4.25Å; L618-V675 CarbonylContact O-C 3.59Å; L618-V675 WeakPolarHBondContact O-CA 3.25Å; L618-K676 PolarHBondContact O-N 2.92Å
619V96Very high86.9Confident0 Ų037.2 Ų37.20%020%0.201CC..EExtended strand (participates in β ladder)trans-124158.7170.1-62.40000108.8H610 D677 I711 M714 Y715 L718H610-V619 HydrophobicContact CB-CG2 4.18Å; H610-V619 PolarHBondContact N-O 2.63Å; H610-V619 PolarHBondContact O-N 3.2Å; V619-D677 WeakPolarHBondContact CA-O 3.47Å; V619-D677 HydrophobicContact CG1-CB 4.49Å; V619-I711 HydrophobicContact CG2-CG2 4.26Å; V619-M714 HydrophobicContact CB-CB 4.26Å; V619-M714 HydrophobicContact CB-CE 3.83Å; V619-M714 HydrophobicContact CB-SD 4.04Å; V619-M714 HydrophobicContact CG1-CB 3.86Å; V619-M714 HydrophobicContact CG2-CE 3.86Å; V619-Y715 HydrophobicContact CG1-CD1 4.07Å; V619-Y715 HydrophobicContact CG1-CE1 3.75Å; V619-Y715 HydrophobicContact CG2-CE1 4.41Å; V619-Y715 HydrophobicContact CG2-CE2 3.86Å; V619-L718 HydrophobicContact CG1-CD1 3.8Å
620A97.3Very high86.4Confident1 Ų138.8 Ų38.81%0.00821%0.212CC..EExtended strand (participates in β ladder)trans-138.5148.6176.500000113.8I607 F608 V609 V675 D677 I678 Y679I607-A620 HydrophobicContact CD1-CB 4.08Å; I607-A620 HydrophobicContact CG1-CB 4.11Å; F608-A620 CarbonylContact O-C 3.59Å; F608-A620 WeakPolarHBondContact O-CA 3.44Å; F608-A620 WeakPolarHBondContact O-CB 3.2Å; V609-A620 HydrophobicContact CG2-CB 4.12Å; A620-V675 HydrophobicContact CB-CG1 3.8Å; A620-V675 HydrophobicContact CB-CG2 3.96Å; A620-D677 PolarHBondContact N-O 2.65Å; A620-I678 HydrophobicContact CB-CG2 4.24Å; A620-I678 CarbonylContact O-C 3.49Å; A620-I678 VanDerWaalsContact O-CA 3.23Å; A620-I678 WeakPolarHBondContact O-CA 3.26Å; A620-Y679 PolarHBondContact O-N 3.09Å
621V97.2Very high85.9Confident1 Ų143.5 Ų43.51%0.00623%0.232CC..EExtended strand (participates in β ladder)trans-98.6125.6166179.20000108I607 F608 Y679 F685 F707I607-V621 CarbonylContact C-O 3.6Å; I607-V621 WeakPolarHBondContact CA-O 3.35Å; F608-V621 HydrophobicContact CB-CB 4.38Å; F608-V621 HydrophobicContact CD1-CB 4.43Å; F608-V621 HydrophobicContact CD1-CG2 4.29Å; F608-V621 PolarHBondContact N-O 2.86Å; F608-V621 PolarHBondContact O-N 3.07Å; V621-Y679 CarbonylContact C-O 3.55Å; V621-Y679 WeakPolarHBondContact CA-O 3.21Å; V621-Y679 HydrophobicContact CG1-CD1 4.03Å; V621-Y679 HydrophobicContact CG2-CD1 4.46Å; V621-F685 HydrophobicContact CB-CZ 4.31Å; V621-F685 HydrophobicContact CG1-CE1 4.05Å; V621-F685 HydrophobicContact CG1-CZ 3.84Å; V621-F707 HydrophobicContact CB-CD2 4.48Å; V621-F707 HydrophobicContact CG1-CD1 4.24Å; V621-F707 HydrophobicContact CG1-CD2 4.15Å; V621-F707 HydrophobicContact CG1-CE1 4.07Å; V621-F707 HydrophobicContact CG1-CE2 3.98Å; V621-F707 HydrophobicContact CG1-CG 4.29Å; V621-F707 HydrophobicContact CG1-CZ 3.94Å; V621-F707 HydrophobicContact CG2-CB 3.94Å; V621-F707 HydrophobicContact CG2-CD1 4.3Å; V621-F707 HydrophobicContact CG2-CD2 4.07Å; V621-F707 HydrophobicContact CG2-CG 3.85Å
622V96.6Very high85.8Confident0 Ų045.3 Ų45.30%024%0.239CC..EExtended strand (participates in β ladder)trans-117.3129.1-175.6174.10000109.2I604 I607 I656 M660 I678 Y679 I680 S681I604-V622 HydrophobicContact CB-CG1 4.34Å; I604-V622 HydrophobicContact CD1-CG1 4.1Å; I604-V622 HydrophobicContact CD1-CG2 4.35Å; I604-V622 HydrophobicContact CG1-CG1 3.72Å; I604-V622 HydrophobicContact CG2-CG1 4.1Å; I607-V622 HydrophobicContact CD1-CG2 4.19Å; I607-V622 HydrophobicContact CG1-CG2 4.21Å; V622-I656 HydrophobicContact CG1-CG2 4.32Å; V622-M660 HydrophobicContact CG2-SD 4.24Å; V622-I678 HydrophobicContact CG2-CB 4.32Å; V622-I678 HydrophobicContact CG2-CG2 4.09Å; V622-Y679 PolarHBondContact N-O 3.5Å; V622-I680 CarbonylContact O-C 3.21Å; V622-I680 WeakPolarHBondContact O-CA 3.4Å; V622-S681 PolarHBondContact O-N 3.25Å
623V94.1Very high86.2Confident10 Ų1043.3 Ų43.36%0.06123%0.228CC..EExtended strand (participates in β ladder)trans-96.4117.2165.7-178.60000107.1S605 Q606 P684 F685S605-V623 PolarHBondContact N-O 3.39Å; Q606-V623 HydrophobicContact CB-CB 3.9Å; Q606-V623 HydrophobicContact CB-CG2 3.97Å; Q606-V623 HydrophobicContact CG-CB 4.45Å; Q606-V623 PolarHBondContact N-O 3.3Å; Q606-V623 PolarHBondContact O-N 3.46Å; V623-P684 HydrophobicContact CG1-CB 4.06Å; V623-F685 HydrophobicContact CG2-CD1 4.02Å; V623-F685 HydrophobicContact CG2-CD2 4.48Å; V623-F685 HydrophobicContact CG2-CE1 3.76Å; V623-F685 HydrophobicContact CG2-CE2 4.27Å; V623-F685 HydrophobicContact CG2-CG 4.36Å; V623-F685 HydrophobicContact CG2-CZ 3.9Å
624P92.1Very high86.8Confident11 Ų1143.2 Ų43.27%0.07123%0.225CC..EExtended strand (participates in β ladder)trans-74.8147-173.730.1-33.4000112F603 M626 L629 L646 I680 S681F603-P624 CarbonylContact O-C 3.43Å; F603-P624 VanDerWaalsContact O-CA 3.29Å; F603-P624 WeakPolarHBondContact O-CA 3.38Å; P624-M626 HydrophobicContact CB-SD 4.27Å; P624-M626 HydrophobicContact CG-CG 4.35Å; P624-M626 HydrophobicContact CG-SD 3.79Å; P624-M626 PolarHBondContact O-N 2.92Å; P624-M626 VanDerWaalsContact O-N 3.14Å; P624-L629 HydrophobicContact CB-CD2 3.71Å; P624-L646 HydrophobicContact CB-CD1 4.47Å; P624-L646 HydrophobicContact CG-CD1 3.87Å; P624-I680 HydrophobicContact CB-CG2 4.28Å; P624-I680 HydrophobicContact CG-CG2 3.79Å; P624-S681 WeakPolarHBondContact CD-O 3.45Å
625N89Confident87.4Confident35 Ų3541.8 Ų41.819%0.18721%0.214CC..  trans-77.592163.2-173.6-26.6000108.8F603 E627 F628 L629F603-N625 PolarHBondContact O-N 2.82Å; N625-E627 VanDerWaalsContact C-N 3.25Å; N625-E627 PolarHBondContact O-N 3.28Å; N625-E627 PolarHBondContact OD1-N 2.66Å; N625-F628 WeakPolarHBondContact ND2-CD2 3.34Å; N625-F628 PolarHBondContact O-N 3.44Å; N625-F628 PolarHBondContact OD1-N 3.21Å; N625-L629 VanDerWaalsContact O-CB 3.24Å; N625-L629 WeakPolarHBondContact O-CB 3.42Å; N625-L629 PolarHBondContact O-N 2.76Å
626M85.6Confident87.5Confident91 Ų9144.4 Ų44.445%0.44823%0.228SC..Hα-helixtrans-62-29.5-173.2-71.4-60.1-69.700113.9P624 S630 L646P624-M626 HydrophobicContact CB-SD 4.27Å; P624-M626 HydrophobicContact CG-CG 4.35Å; P624-M626 HydrophobicContact CG-SD 3.79Å; P624-M626 PolarHBondContact O-N 2.92Å; P624-M626 VanDerWaalsContact O-N 3.14Å; M626-S630 WeakPolarHBondContact O-CB 3.4Å; M626-S630 PolarHBondContact O-N 3.3Å; M626-S630 PolarHBondContact O-OG 2.89Å; M626-L646 HydrophobicContact CE-CD1 4.4Å; M626-L646 HydrophobicContact SD-CD1 3.78Å
627E82.5Confident87.5Confident133 Ų13344.4 Ų44.462%0.62122%0.221SC*.Hα-helixtrans-64.3-49.1179.1-172.9177.1177.500110.8N625N625-E627 VanDerWaalsContact C-N 3.25Å; N625-E627 PolarHBondContact O-N 3.28Å; N625-E627 PolarHBondContact OD1-N 2.66Å
628F82.2Confident87.1Confident48 Ų4849.9 Ų49.921%0.21125%0.249CC..Hα-helixtrans-76.6-42.3178.1-81.7-89.6000113.1L399 K602 N625 K631 H632L399-F628 HydrophobicContact CD1-CE2 3.77Å; L399-F628 HydrophobicContact CD1-CZ 3.75Å; L399-F628 HydrophobicContact CD2-CD1 4.26Å; L399-F628 HydrophobicContact CD2-CE1 3.34Å; L399-F628 HydrophobicContact CD2-CE2 3.83Å; L399-F628 HydrophobicContact CD2-CZ 3.14Å; L399-F628 HydrophobicContact CG-CE1 4.06Å; L399-F628 HydrophobicContact CG-CE2 3.93Å; L399-F628 HydrophobicContact CG-CZ 3.35Å; K602-F628 WeakPolarHBondContact O-CB 3.22Å; N625-F628 WeakPolarHBondContact ND2-CD2 3.34Å; N625-F628 PolarHBondContact O-N 3.44Å; N625-F628 PolarHBondContact OD1-N 3.21Å; F628-K631 PolarHBondContact O-N 3.12Å; F628-H632 WeakPolarHBondContact O-CB 3.25Å; F628-H632 PolarHBondContact O-N 2.87Å
629L85.8Confident86.3Confident1 Ų151.9 Ų51.91%0.00526%0.259CS..Hα-helixtrans-61.7-50-177.9-178.262.9000110.4F603 P624 N625 K631 H632 L633 L646 V652 L655 I656F603-L629 HydrophobicContact CD1-CB 4.49Å; F603-L629 HydrophobicContact CD1-CD1 3.9Å; F603-L629 HydrophobicContact CE1-CD1 4.43Å; P624-L629 HydrophobicContact CB-CD2 3.71Å; N625-L629 VanDerWaalsContact O-CB 3.24Å; N625-L629 WeakPolarHBondContact O-CB 3.42Å; N625-L629 PolarHBondContact O-N 2.76Å; L629-K631 VanDerWaalsContact C-N 3.29Å; L629-K631 PolarHBondContact O-N 2.82Å; L629-H632 PolarHBondContact O-N 3.23Å; L629-H632 VanDerWaalsContact O-N 3.16Å; L629-L633 HydrophobicContact CD1-CD1 4.14Å; L629-L633 HydrophobicContact CD1-CD2 4.14Å; L629-L633 HydrophobicContact CD1-CG 3.98Å; L629-L633 HydrophobicContact CG-CD1 3.92Å; L629-L633 HydrophobicContact CG-CG 4.15Å; L629-L633 VanDerWaalsContact O-CG 3.26Å; L629-L633 WeakPolarHBondContact O-CG 3.34Å; L629-L633 PolarHBondContact O-N 3.23Å; L629-L646 HydrophobicContact CD2-CD1 4Å; L629-V652 HydrophobicContact CD1-CG1 4.48Å; L629-V652 HydrophobicContact CD2-CG1 4.26Å; L629-L655 HydrophobicContact CD1-CD2 4.2Å; L629-I656 HydrophobicContact CD2-CD1 4.36Å
630S84.7Confident85.3Confident33 Ų3360.2 Ų60.223%0.23130%0.298CS..Hα-helixtrans-61.4-40-177.5-52.80000112.2M626 T634M626-S630 WeakPolarHBondContact O-CB 3.4Å; M626-S630 PolarHBondContact O-N 3.3Å; M626-S630 PolarHBondContact O-OG 2.89Å; S630-T634 WeakPolarHBondContact O-CB 3.48Å; S630-T634 PolarHBondContact O-N 3.48Å; S630-T634 VanDerWaalsContact O-N 3.07Å; S630-T634 PolarHBondContact O-OG1 3.36Å
631K82.1Confident84.3Confident115 Ų11567.4 Ų67.450%0.534%0.336SS..Hα-helixtrans-60.9-50.3175.1-174.4178.6177.9-177.90111.3F628 L629 L633 T634 E635F628-K631 PolarHBondContact O-N 3.12Å; L629-K631 VanDerWaalsContact C-N 3.29Å; L629-K631 PolarHBondContact O-N 2.82Å; K631-L633 PolarHBondContact O-N 3.13Å; K631-T634 PolarHBondContact O-N 3.37Å; K631-E635 VanDerWaalsContact CE-CD 3.41Å; K631-E635 WeakPolarHBondContact CE-OE1 3.2Å; K631-E635 WeakPolarHBondContact CE-OE2 3.46Å; K631-E635 HydrophobicContact CG-CG 4.31Å; K631-E635 WeakPolarHBondContact CG-OE1 3.38Å; K631-E635 WeakPolarHBondContact CG-OE2 3.41Å; K631-E635 WeakPolarHBondContact O-CB 3.46Å; K631-E635 WeakPolarHBondContact O-CG 3.44Å; K631-E635 PolarHBondContact O-N 2.97Å
632H82.4Confident83.2Confident44 Ų4469.8 Ų69.820%0.20435%0.348CS..Hα-helixtrans-64-41.7179.9-169.881.2000112.7F603 F628 L629 T634 E636 L637F603-H632 HydrophobicContact CE1-CB 3.82Å; F603-H632 AromaticContact CE1-CD2 3.77Å; F603-H632 AromaticContact CE1-CG 3.7Å; F603-H632 AromaticContact CZ-CD2 3.72Å; F603-H632 AromaticContact CZ-CG 3.91Å; F603-H632 AromaticContact CZ-NE2 3.89Å; F628-H632 WeakPolarHBondContact O-CB 3.25Å; F628-H632 PolarHBondContact O-N 2.87Å; L629-H632 PolarHBondContact O-N 3.23Å; L629-H632 VanDerWaalsContact O-N 3.16Å; H632-T634 VanDerWaalsContact C-N 3.3Å; H632-T634 PolarHBondContact O-N 3.18Å; H632-E636 WeakPolarHBondContact O-CB 3.46Å; H632-E636 PolarHBondContact O-N 3.24Å; H632-L637 PolarHBondContact O-N 3.48Å
633L85.2Confident82.1Confident0 Ų071.7 Ų71.70%036%0.361CS..Hα-helixtrans-62.1-38.7177.1-65.4-178.4000111.9L629 K631 L637 N638 M639 I642 V652 L655L629-L633 HydrophobicContact CD1-CD1 4.14Å; L629-L633 HydrophobicContact CD1-CD2 4.14Å; L629-L633 HydrophobicContact CD1-CG 3.98Å; L629-L633 HydrophobicContact CG-CD1 3.92Å; L629-L633 HydrophobicContact CG-CG 4.15Å; L629-L633 VanDerWaalsContact O-CG 3.26Å; L629-L633 WeakPolarHBondContact O-CG 3.34Å; L629-L633 PolarHBondContact O-N 3.23Å; K631-L633 PolarHBondContact O-N 3.13Å; L633-L637 HydrophobicContact CD2-CD1 3.81Å; L633-L637 CarbonylContact O-C 3.58Å; L633-L637 WeakPolarHBondContact O-CB 3.25Å; L633-L637 PolarHBondContact O-N 3.44Å; L633-N638 PolarHBondContact O-N 3.24Å; L633-M639 HydrophobicContact CB-CB 4.42Å; L633-M639 HydrophobicContact CD2-CE 3.8Å; L633-M639 PolarHBondContact O-N 3.07Å; L633-I642 HydrophobicContact CB-CD1 4.33Å; L633-I642 HydrophobicContact CB-CG1 4.4Å; L633-I642 HydrophobicContact CD1-CD1 4.33Å; L633-I642 HydrophobicContact CD1-CG1 4.27Å; L633-I642 HydrophobicContact CD1-CG2 4.03Å; L633-V652 HydrophobicContact CD1-CG2 3.88Å; L633-V652 HydrophobicContact CD2-CG2 3.94Å; L633-L655 HydrophobicContact CD2-CD2 3.93Å
634T82.9Confident81.2Confident62 Ų6276.3 Ų76.338%0.3840%0.4SS..Hα-helixtrans-75.7-47.6-179.4-50.50000111.8S630 K631 H632 N638S630-T634 WeakPolarHBondContact O-CB 3.48Å; S630-T634 PolarHBondContact O-N 3.48Å; S630-T634 VanDerWaalsContact O-N 3.07Å; S630-T634 PolarHBondContact O-OG1 3.36Å; K631-T634 PolarHBondContact O-N 3.37Å; H632-T634 VanDerWaalsContact C-N 3.3Å; H632-T634 PolarHBondContact O-N 3.18Å; T634-N638 WeakPolarHBondContact O-CA 3.47Å; T634-N638 PolarHBondContact O-N 3.24Å
635E82.4Confident80.8Confident119 Ų11979.9 Ų79.956%0.55642%0.418SS*.Hα-helixtrans-80.8-41.2-172.2-67.7177.5177.600113.1K631K631-E635 VanDerWaalsContact CE-CD 3.41Å; K631-E635 WeakPolarHBondContact CE-OE1 3.2Å; K631-E635 WeakPolarHBondContact CE-OE2 3.46Å; K631-E635 HydrophobicContact CG-CG 4.31Å; K631-E635 WeakPolarHBondContact CG-OE1 3.38Å; K631-E635 WeakPolarHBondContact CG-OE2 3.41Å; K631-E635 WeakPolarHBondContact O-CB 3.46Å; K631-E635 WeakPolarHBondContact O-CG 3.44Å; K631-E635 PolarHBondContact O-N 2.97Å
636E80.2Confident80.6Confident130 Ų13078.8 Ų78.861%0.60741%0.413SS*.THydrogen-bonded Turntrans-99.4-35.6-172.2-61.6-69.9164.200112.4H632H632-E636 WeakPolarHBondContact O-CB 3.46Å; H632-E636 PolarHBondContact O-N 3.24Å
637L78.5Confident80.7Confident80 Ų8075.5 Ų75.542%0.41940%0.397SS..SBendtrans-101.10.6-179.7-65.1-179.8000113.9H632 L633 M639 L655H632-L637 PolarHBondContact O-N 3.48Å; L633-L637 HydrophobicContact CD2-CD1 3.81Å; L633-L637 CarbonylContact O-C 3.58Å; L633-L637 WeakPolarHBondContact O-CB 3.25Å; L633-L637 PolarHBondContact O-N 3.44Å; L637-M639 HydrophobicContact CB-CE 3.87Å; L637-M639 HydrophobicContact CD1-CE 3.69Å; L637-M639 HydrophobicContact CG-CE 4.44Å; L637-M639 PolarHBondContact O-N 2.96Å; L637-M639 VanDerWaalsContact O-N 3.1Å; L637-L655 HydrophobicContact CD1-CD2 4.23Å
638N79Confident80.7Confident133 Ų13373 Ų7371%0.71139%0.394SS*.  trans52.227.8-178.3-68-57.8000114.2L633 T634 Q640L633-N638 PolarHBondContact O-N 3.24Å; T634-N638 WeakPolarHBondContact O-CA 3.47Å; T634-N638 PolarHBondContact O-N 3.24Å; N638-Q640 PolarHBondContact O-N 2.72Å
639M77.6Confident80.9Confident43 Ų4371.6 Ų71.621%0.21239%0.39CS..  trans-83.194.9175.1-94.7-174.4-85.900110.1L633 L637 A651 V652L633-M639 HydrophobicContact CB-CB 4.42Å; L633-M639 HydrophobicContact CD2-CE 3.8Å; L633-M639 PolarHBondContact O-N 3.07Å; L637-M639 HydrophobicContact CB-CE 3.87Å; L637-M639 HydrophobicContact CD1-CE 3.69Å; L637-M639 HydrophobicContact CG-CE 4.44Å; L637-M639 PolarHBondContact O-N 2.96Å; L637-M639 VanDerWaalsContact O-N 3.1Å; M639-A651 HydrophobicContact CE-CB 4.43Å; M639-V652 HydrophobicContact CE-CG2 4.33Å
640Q73.6Confident81Confident175 Ų17578.2 Ų78.282%0.81842%0.421SS*.SBendtrans-72.9-33.7176.9-67.2-171.7-5.700113.2N638N638-Q640 PolarHBondContact O-N 2.72Å
641N76.6Confident81.1Confident152 Ų15279.3 Ų79.381%0.81343%0.432SS*.SBendtrans-105.685.8178.5-72.9-23.8000109.8P643N641-P643 WeakPolarHBondContact O-CD 3.27Å
642I75.1Confident81.5Confident50 Ų5073.8 Ų73.826%0.25641%0.408SS..  trans-65.8122174.6-58.2173.3000108.2L633 L646L633-I642 HydrophobicContact CB-CD1 4.33Å; L633-I642 HydrophobicContact CB-CG1 4.4Å; L633-I642 HydrophobicContact CD1-CD1 4.33Å; L633-I642 HydrophobicContact CD1-CG1 4.27Å; L633-I642 HydrophobicContact CD1-CG2 4.03Å; I642-L646 HydrophobicContact CG2-CD2 3.65Å
643P71.8Confident82Confident41 Ų4173.1 Ų73.127%0.26640%0.404SS..  trans-58139.2178.9-24.734.7000111.7N641 D645N641-P643 WeakPolarHBondContact O-CD 3.27Å; P643-D645 VanDerWaalsContact C-N 3.28Å; P643-D645 PolarHBondContact O-N 3.2Å
644A76.5Confident82.3Confident107 Ų10779.5 Ų79.588%0.88443%0.432SS*.SBendtrans-62.5-37.7175.400000111.9
645D83.4Confident82.8Confident85 Ų8578.3 Ų78.346%0.45542%0.423SS..SBendtrans-97.6101.6167.8177.616.5000110P643 N647 S648P643-D645 VanDerWaalsContact C-N 3.28Å; P643-D645 PolarHBondContact O-N 3.2Å; D645-N647 PolarHBondContact O-N 3.15Å; D645-N647 VanDerWaalsContact OD1-CB 3.32Å; D645-N647 WeakPolarHBondContact OD1-CB 3.2Å; D645-N647 PolarHBondContact OD1-N 3.21Å; D645-N647 PolarHBondContact OD1-ND2 2.7Å; D645-N647 VanDerWaalsContact OD1-ND2 3.14Å; D645-S648 WeakPolarHBondContact O-CB 3.37Å; D645-S648 PolarHBondContact O-N 3.49Å; D645-S648 VanDerWaalsContact O-N 3.15Å; D645-S648 PolarHBondContact O-OG 3.41Å
646L84.9Confident83.4Confident13 Ų1372.6 Ų72.67%0.06840%0.397CS..G310 helixtrans-63.9-22.2179.4-63.6174.9000113P624 M626 L629 I642 S648 S649 V652 I680P624-L646 HydrophobicContact CB-CD1 4.47Å; P624-L646 HydrophobicContact CG-CD1 3.87Å; M626-L646 HydrophobicContact CE-CD1 4.4Å; M626-L646 HydrophobicContact SD-CD1 3.78Å; L629-L646 HydrophobicContact CD2-CD1 4Å; I642-L646 HydrophobicContact CG2-CD2 3.65Å; L646-S648 PolarHBondContact O-N 3.02Å; L646-S649 PolarHBondContact O-N 2.93Å; L646-V652 HydrophobicContact CD2-CG1 4.47Å; L646-I680 HydrophobicContact CB-CB 4.28Å; L646-I680 HydrophobicContact CB-CD1 4.14Å; L646-I680 HydrophobicContact CB-CG2 3.87Å; L646-I680 HydrophobicContact CD1-CG2 3.93Å
647N86.3Confident84.1Confident21 Ų2167.7 Ų67.711%0.11237%0.374CS..G310 helixtrans-68.9-22.9176.5-67.2-78.9000113.3D645 S649 K653 Y679 I680D645-N647 PolarHBondContact O-N 3.15Å; D645-N647 VanDerWaalsContact OD1-CB 3.32Å; D645-N647 WeakPolarHBondContact OD1-CB 3.2Å; D645-N647 PolarHBondContact OD1-N 3.21Å; D645-N647 PolarHBondContact OD1-ND2 2.7Å; D645-N647 VanDerWaalsContact OD1-ND2 3.14Å; N647-S649 PolarHBondContact O-N 2.97Å; N647-K653 WeakPolarHBondContact OD1-CE 3.49Å; N647-Y679 HydrophobicContact CB-CE2 4.46Å; N647-Y679 VanDerWaalsContact CG-CE2 3.5Å; N647-Y679 VanDerWaalsContact ND2-CE2 3.32Å; N647-Y679 WeakPolarHBondContact ND2-CE2 3.27Å; N647-Y679 WeakPolarHBondContact OD1-CD2 3.44Å; N647-I680 PolarHBondContact ND2-O 3.42Å; N647-I680 PolarHBondContact OD1-N 3.38Å
648S84.2Confident84.9Confident80 Ų8067.5 Ų67.556%0.55937%0.374SS*.G310 helixtrans-71.5-14.3177.570.20000112.9D645 L646D645-S648 WeakPolarHBondContact O-CB 3.37Å; D645-S648 PolarHBondContact O-N 3.49Å; D645-S648 VanDerWaalsContact O-N 3.15Å; D645-S648 PolarHBondContact O-OG 3.41Å; L646-S648 PolarHBondContact O-N 3.02Å
649S86.4Confident85.6Confident19 Ų1962.7 Ų62.713%0.13335%0.348CS..  trans-101.9101.4179.8-1750000111.7L646 N647 A651 V652 K653L646-S649 PolarHBondContact O-N 2.93Å; N647-S649 PolarHBondContact O-N 2.97Å; S649-A651 PolarHBondContact O-N 3.3Å; S649-V652 PolarHBondContact O-N 3.12Å; S649-V652 VanDerWaalsContact O-N 3.1Å; S649-V652 WeakPolarHBondContact OG-CG2 3.46Å; S649-V652 PolarHBondContact OG-N 3.07Å; S649-K653 PolarHBondContact O-N 3.44Å
650E86.8Confident86.5Confident141 Ų14160.6 Ų60.666%0.65934%0.338SS*.Hα-helixtrans-55.2-33.1170.9-71.4-59.113400112.3K654E650-K654 WeakPolarHBondContact O-CB 3.39Å; E650-K654 PolarHBondContact O-N 3.44Å
651A87.3Confident87.5Confident55 Ų5554 Ų5446%0.45531%0.307SS..Hα-helixtrans-64.5-42.7177.100000112.1M639 S649 L655M639-A651 HydrophobicContact CE-CB 4.43Å; S649-A651 PolarHBondContact O-N 3.3Å; A651-L655 WeakPolarHBondContact O-CB 3.43Å; A651-L655 PolarHBondContact O-N 2.85Å
652V90.2Very high88.3Confident0 Ų053.3 Ų53.30%030%0.299CS..Hα-helixtrans-69.8-45178.8177.90000110.6L629 L633 M639 L646 S649 K654 L655 I656 I680L629-V652 HydrophobicContact CD1-CG1 4.48Å; L629-V652 HydrophobicContact CD2-CG1 4.26Å; L633-V652 HydrophobicContact CD1-CG2 3.88Å; L633-V652 HydrophobicContact CD2-CG2 3.94Å; M639-V652 HydrophobicContact CE-CG2 4.33Å; L646-V652 HydrophobicContact CD2-CG1 4.47Å; S649-V652 PolarHBondContact O-N 3.12Å; S649-V652 VanDerWaalsContact O-N 3.1Å; S649-V652 WeakPolarHBondContact OG-CG2 3.46Å; S649-V652 PolarHBondContact OG-N 3.07Å; V652-K654 PolarHBondContact O-N 3.23Å; V652-L655 WeakPolarHBondContact O-CB 3.32Å; V652-L655 PolarHBondContact O-N 2.87Å; V652-I656 HydrophobicContact CG1-CD1 4.2Å; V652-I656 PolarHBondContact O-N 3.31Å; V652-I656 VanDerWaalsContact O-N 3.16Å; V652-I680 HydrophobicContact CG1-CD1 3.86Å
653K92.7Very high88.9Confident29 Ų2952.6 Ų52.613%0.12630%0.295CS..Hα-helixtrans-57.4-48.4175-80.3-169.9169.2-150.10111.9N647 S649 L655 I656 L657 I678 I680N647-K653 WeakPolarHBondContact OD1-CE 3.49Å; S649-K653 PolarHBondContact O-N 3.44Å; K653-L655 VanDerWaalsContact C-N 3.33Å; K653-L655 PolarHBondContact O-N 3.3Å; K653-I656 PolarHBondContact O-N 2.84Å; K653-L657 VanDerWaalsContact O-CB 3.31Å; K653-L657 WeakPolarHBondContact O-CB 3.38Å; K653-L657 PolarHBondContact O-N 3.4Å; K653-I678 VanDerWaalsContact CE-O 3.28Å; K653-I678 WeakPolarHBondContact CE-O 3.46Å; K653-I678 PolarHBondContact NZ-O 3.45Å; K653-I680 HydrophobicContact CG-CD1 3.74Å; K653-I680 HydrophobicContact CG-CG1 4.26Å
654K92.8Very high89.6Confident135 Ų13550.6 Ų50.659%0.58728%0.282SS*.Hα-helixtrans-64.3-37-179.4-170.1172.6-176.1175.60112.4E650 V652 N658E650-K654 WeakPolarHBondContact O-CB 3.39Å; E650-K654 PolarHBondContact O-N 3.44Å; V652-K654 PolarHBondContact O-N 3.23Å; K654-N658 VanDerWaalsContact O-CB 3.23Å; K654-N658 WeakPolarHBondContact O-CB 3.46Å; K654-N658 PolarHBondContact O-N 3.41Å; K654-N658 PolarHBondContact O-ND2 2.92Å
655L92.8Very high90.2Very high36 Ų3652.2 Ų52.219%0.18827%0.269CS..Hα-helixtrans-58-53.5174173.969.1000111.1F603 L629 L633 L637 A651 V652 K653 D659F603-L655 HydrophobicContact CE1-CD2 4.34Å; F603-L655 HydrophobicContact CE2-CD1 4.39Å; F603-L655 HydrophobicContact CE2-CG 4.33Å; F603-L655 HydrophobicContact CZ-CD1 4.31Å; F603-L655 HydrophobicContact CZ-CD2 4.19Å; F603-L655 HydrophobicContact CZ-CG 4.33Å; L629-L655 HydrophobicContact CD1-CD2 4.2Å; L633-L655 HydrophobicContact CD2-CD2 3.93Å; L637-L655 HydrophobicContact CD1-CD2 4.23Å; A651-L655 WeakPolarHBondContact O-CB 3.43Å; A651-L655 PolarHBondContact O-N 2.85Å; V652-L655 WeakPolarHBondContact O-CB 3.32Å; V652-L655 PolarHBondContact O-N 2.87Å; K653-L655 VanDerWaalsContact C-N 3.33Å; K653-L655 PolarHBondContact O-N 3.3Å; L655-D659 PolarHBondContact O-N 2.65Å; L655-D659 VanDerWaalsContact O-N 3.14Å
656I94.4Very high90.3Very high0 Ų057 Ų570%029%0.286CS..Hα-helixtrans-65.5-44.7-178.1-62.8172.6000110.5F603 I604 V622 L629 V652 K653 N658 D659 M660 I678 I680F603-I656 HydrophobicContact CB-CG1 4.19Å; I604-I656 HydrophobicContact CD1-CG2 4.15Å; I604-I656 HydrophobicContact CG1-CG2 4.18Å; V622-I656 HydrophobicContact CG1-CG2 4.32Å; L629-I656 HydrophobicContact CD2-CD1 4.36Å; V652-I656 HydrophobicContact CG1-CD1 4.2Å; V652-I656 PolarHBondContact O-N 3.31Å; V652-I656 VanDerWaalsContact O-N 3.16Å; K653-I656 PolarHBondContact O-N 2.84Å; I656-N658 PolarHBondContact O-N 3.22Å; I656-D659 PolarHBondContact O-N 2.9Å; I656-M660 HydrophobicContact CG2-SD 4.14Å; I656-M660 WeakPolarHBondContact O-CG 2.9Å; I656-M660 PolarHBondContact O-N 2.83Å; I656-I678 HydrophobicContact CB-CD1 3.73Å; I656-I678 HydrophobicContact CG2-CD1 3.63Å; I656-I680 HydrophobicContact CD1-CD1 3.86Å; I656-I680 HydrophobicContact CD1-CG1 4.3Å
657L95.4Very high90Very high27 Ų2759.8 Ų59.814%0.14131%0.307CS..Hα-helixtrans-63.7-41.1-179.4-173.568000112.4K653 M660 H661 V675 I678K653-L657 VanDerWaalsContact O-CB 3.31Å; K653-L657 WeakPolarHBondContact O-CB 3.38Å; K653-L657 PolarHBondContact O-N 3.4Å; L657-M660 WeakPolarHBondContact O-CB 3.31Å; L657-M660 PolarHBondContact O-N 3.13Å; L657-H661 PolarHBondContact O-N 2.89Å; L657-V675 HydrophobicContact CD1-CG1 4.32Å; L657-I678 HydrophobicContact CB-CD1 4.26Å; L657-I678 HydrophobicContact CD1-CG2 4.01Å
658N95.4Very high89.6Confident75 Ų7561.6 Ų61.640%0.40133%0.331SS..Hα-helixtrans-64-43.4176.2-75-12.8000111.6K654 I656 M660 H661 E662K654-N658 VanDerWaalsContact O-CB 3.23Å; K654-N658 WeakPolarHBondContact O-CB 3.46Å; K654-N658 PolarHBondContact O-N 3.41Å; K654-N658 PolarHBondContact O-ND2 2.92Å; I656-N658 PolarHBondContact O-N 3.22Å; N658-M660 VanDerWaalsContact C-N 3.32Å; N658-M660 PolarHBondContact O-N 3.03Å; N658-H661 PolarHBondContact O-N 3.34Å; N658-E662 WeakPolarHBondContact O-CG 3.39Å; N658-E662 PolarHBondContact O-N 2.61Å
659D93.3Very high89.4Confident32 Ų3258.3 Ų58.317%0.17131%0.307CS..Hα-helixtrans-60.3-42.6175.8-174.984.5000111S601 F603 L655 I656 H661 E662 L663S601-D659 WeakPolarHBondContact CB-OD2 3.02Å; S601-D659 PolarHBondContact OG-OD2 2.95Å; F603-D659 HydrophobicContact CD2-CB 4.04Å; F603-D659 HydrophobicContact CE2-CB 4.12Å; L655-D659 PolarHBondContact O-N 2.65Å; L655-D659 VanDerWaalsContact O-N 3.14Å; I656-D659 PolarHBondContact O-N 2.9Å; D659-H661 PolarHBondContact O-N 2.84Å; D659-E662 PolarHBondContact O-N 2.95Å; D659-L663 WeakPolarHBondContact O-CG 3.34Å; D659-L663 PolarHBondContact O-N 2.9Å
660M95.7Very high89Confident0 Ų060.2 Ų60.20%032%0.319CS..Hα-helixtrans-60.3-43.7172.6-70.5173.563.600112.6Y598 I604 I607 V622 I656 L657 N658 L663 G664 V675 I678Y598-M660 HydrophobicContact CD1-CB 3.8Å; Y598-M660 HydrophobicContact CD1-CE 3.95Å; Y598-M660 HydrophobicContact CD1-CG 4.01Å; Y598-M660 HydrophobicContact CD2-CE 3.77Å; Y598-M660 HydrophobicContact CE1-CB 3.97Å; Y598-M660 HydrophobicContact CE1-CE 4.19Å; Y598-M660 WeakPolarHBondContact CE1-O 2.78Å; Y598-M660 HydrophobicContact CE2-CE 4.02Å; Y598-M660 HydrophobicContact CG-CE 3.75Å; Y598-M660 HydrophobicContact CG-CG 4.38Å; I604-M660 HydrophobicContact CD1-CG 3.68Å; I604-M660 HydrophobicContact CD1-SD 3.77Å; I607-M660 HydrophobicContact CD1-CE 3.62Å; I607-M660 HydrophobicContact CD1-SD 4.47Å; V622-M660 HydrophobicContact CG2-SD 4.24Å; I656-M660 HydrophobicContact CG2-SD 4.14Å; I656-M660 WeakPolarHBondContact O-CG 2.9Å; I656-M660 PolarHBondContact O-N 2.83Å; L657-M660 WeakPolarHBondContact O-CB 3.31Å; L657-M660 PolarHBondContact O-N 3.13Å; N658-M660 VanDerWaalsContact C-N 3.32Å; N658-M660 PolarHBondContact O-N 3.03Å; M660-L663 PolarHBondContact O-N 2.75Å; M660-G664 PolarHBondContact O-N 3.48Å; M660-V675 HydrophobicContact CE-CB 4.01Å; M660-V675 HydrophobicContact CE-CG1 4.23Å; M660-V675 HydrophobicContact CE-CG2 4.06Å; M660-I678 HydrophobicContact CE-CG2 4.26Å; M660-I678 HydrophobicContact SD-CG2 3.95Å
661H95.7Very high88.9Confident37 Ų3757.6 Ų57.617%0.17132%0.317CS..Hα-helixtrans-65.9-38.8177.8-71.5175.6000112.6L657 N658 D659 G664 K665 V675L657-H661 PolarHBondContact O-N 2.89Å; N658-H661 PolarHBondContact O-N 3.34Å; D659-H661 PolarHBondContact O-N 2.84Å; H661-G664 PolarHBondContact O-N 3.4Å; H661-K665 WeakPolarHBondContact O-CB 3.07Å; H661-K665 VanDerWaalsContact O-CG 3.3Å; H661-K665 WeakPolarHBondContact O-CG 3.45Å; H661-K665 PolarHBondContact O-N 2.98Å; H661-V675 PolarHBondContact NE2-O 3.46Å
662E93.3Very high88.6Confident136 Ų13657.7 Ų57.764%0.63631%0.307SS*.Hα-helixtrans-63.7-46.8175.3-74.5-177-174.700111.3N658 D659 K665 K666N658-E662 WeakPolarHBondContact O-CG 3.39Å; N658-E662 PolarHBondContact O-N 2.61Å; D659-E662 PolarHBondContact O-N 2.95Å; E662-K665 PolarHBondContact O-N 3.46Å; E662-K666 WeakPolarHBondContact O-CB 3.34Å; E662-K666 PolarHBondContact O-N 2.94Å
663L88.4Confident88.4Confident35 Ų3558.5 Ų58.518%0.18331%0.311CS..Hα-helixtrans-59.8-46.9173.9-72.7171.5000111.5V597 H600 D659 M660 K665 K666 S667V597-L663 HydrophobicContact CG1-CB 4.42Å; H600-L663 HydrophobicContact CB-CD1 4.41Å; H600-L663 HydrophobicContact CB-CD2 4.34Å; D659-L663 WeakPolarHBondContact O-CG 3.34Å; D659-L663 PolarHBondContact O-N 2.9Å; M660-L663 PolarHBondContact O-N 2.75Å; L663-K665 PolarHBondContact O-N 2.97Å; L663-K666 PolarHBondContact O-N 3.32Å; L663-S667 WeakPolarHBondContact O-CB 3.17Å; L663-S667 PolarHBondContact O-N 3.3Å; L663-S667 PolarHBondContact O-OG 3.42Å
664G85.4Confident88.3Confident0 Ų057.9 Ų57.90%031%0.308CS..Hα-helixtrans-59-47179.400000112.8M660 H661 K666 S667 G668 L669M660-G664 PolarHBondContact O-N 3.48Å; H661-G664 PolarHBondContact O-N 3.4Å; G664-K666 PolarHBondContact O-N 3.18Å; G664-S667 CarbonylContact O-C 3.54Å; G664-S667 PolarHBondContact O-N 3.46Å; G664-G668 PolarHBondContact O-N 3.5Å; G664-G668 VanDerWaalsContact O-N 3.17Å; G664-L669 VanDerWaalsContact O-CB 3.32Å; G664-L669 WeakPolarHBondContact O-CB 3.5Å; G664-L669 WeakPolarHBondContact O-CG 3.36Å; G664-L669 PolarHBondContact O-N 2.94Å
665K89.2Confident88.4Confident141 Ų14151.4 Ų51.461%0.61328%0.28SS*.Hα-helixtrans-62.1-43.5175.5-71.8171.5-173.1171.10111.9H661 E662 L663 S667 G668H661-K665 WeakPolarHBondContact O-CB 3.07Å; H661-K665 VanDerWaalsContact O-CG 3.3Å; H661-K665 WeakPolarHBondContact O-CG 3.45Å; H661-K665 PolarHBondContact O-N 2.98Å; E662-K665 PolarHBondContact O-N 3.46Å; L663-K665 PolarHBondContact O-N 2.97Å; K665-S667 VanDerWaalsContact C-N 3.25Å; K665-S667 PolarHBondContact O-N 2.76Å; K665-G668 PolarHBondContact O-N 2.87Å; K665-G668 VanDerWaalsContact O-N 3.1Å
666K85.2Confident88.5Confident185 Ų18553.9 Ų53.980%0.80429%0.289SS*.Hα-helixtrans-63.7-33179-171.8-179176.6-171.50112.1E662 L663 G664 G668E662-K666 WeakPolarHBondContact O-CB 3.34Å; E662-K666 PolarHBondContact O-N 2.94Å; L663-K666 PolarHBondContact O-N 3.32Å; G664-K666 PolarHBondContact O-N 3.18Å; K666-G668 VanDerWaalsContact C-N 3.32Å
667S78.2Confident88.6Confident71 Ų7155.2 Ų55.250%0.49730%0.296SS..THydrogen-bonded Turntrans-86.84.7175.6-64.30000114.2L663 G664 K665L663-S667 WeakPolarHBondContact O-CB 3.17Å; L663-S667 PolarHBondContact O-N 3.3Å; L663-S667 PolarHBondContact O-OG 3.42Å; G664-S667 CarbonylContact O-C 3.54Å; G664-S667 PolarHBondContact O-N 3.46Å; K665-S667 VanDerWaalsContact C-N 3.25Å; K665-S667 PolarHBondContact O-N 2.76Å
668G77.8Confident88.6Confident60 Ų6054 Ų5462%0.61929%0.29SS*.THydrogen-bonded Turntrans77.919.8176.100000115.3G664 K665 K666G664-G668 PolarHBondContact O-N 3.5Å; G664-G668 VanDerWaalsContact O-N 3.17Å; K665-G668 PolarHBondContact O-N 2.87Å; K665-G668 VanDerWaalsContact O-N 3.1Å; K666-G668 VanDerWaalsContact C-N 3.32Å
669L80.8Confident88.7Confident11 Ų1152.9 Ų52.96%0.05828%0.28CS..  trans-68.9132176.5-61.3-174.4000111.4L594 V597 Y598 G664 E673 Q674L594-L669 HydrophobicContact CD2-CD1 3.77Å; L594-L669 HydrophobicContact CD2-CD2 3.59Å; L594-L669 HydrophobicContact CD2-CG 4.28Å; V597-L669 HydrophobicContact CB-CD1 4.4Å; V597-L669 HydrophobicContact CG1-CD1 4.14Å; Y598-L669 HydrophobicContact CE1-CD1 4.26Å; G664-L669 VanDerWaalsContact O-CB 3.32Å; G664-L669 WeakPolarHBondContact O-CB 3.5Å; G664-L669 WeakPolarHBondContact O-CG 3.36Å; G664-L669 PolarHBondContact O-N 2.94Å; L669-E673 WeakPolarHBondContact CA-OE2 3.4Å; L669-E673 HydrophobicContact CB-CB 4.13Å; L669-Q674 HydrophobicContact CB-CG 4.34Å; L669-Q674 PolarHBondContact O-NE2 3.36Å
670C79.1Confident88.8Confident59 Ų5951.4 Ų51.440%0.39927%0.273SS..  trans-63.5160.8174.2-65.90000111.6F672 E673 Q674C670-F672 HydrophobicContact CB-CD1 3.69Å; C670-F672 HydrophobicContact CB-CD2 4.46Å; C670-F672 HydrophobicContact CB-CE1 3.3Å; C670-F672 HydrophobicContact CB-CE2 4.15Å; C670-F672 HydrophobicContact CB-CG 4.26Å; C670-F672 HydrophobicContact CB-CZ 3.56Å; C670-F672 PolarHBondContact O-N 2.69Å; C670-E673 HydrophobicContact CB-CG 4.2Å; C670-E673 PolarHBondContact N-OE2 2.81Å; C670-E673 WeakPolarHBondContact O-CB 3.5Å; C670-E673 PolarHBondContact O-N 3.29Å; C670-Q674 PolarHBondContact O-N 3.44Å
671S83.8Confident88.7Confident86 Ų8651.6 Ų51.660%0.60127%0.274SS*.THydrogen-bonded Turntrans-61.4-29.8-177.6620000113.7K676S671-K676 PolarHBondContact O-NZ 3.42Å
672F80.2Confident88.3Confident57 Ų5754.9 Ų54.925%0.2530%0.301CS..THydrogen-bonded Turntrans-81-21176.761.4-99.6000113.3E587 I589 C670 Q674E587-F672 HydrophobicContact CB-CD2 4.03Å; E587-F672 HydrophobicContact CB-CE2 4.06Å; E587-F672 HydrophobicContact CG-CD1 4.47Å; E587-F672 HydrophobicContact CG-CD2 4.16Å; E587-F672 HydrophobicContact CG-CE1 4.49Å; E587-F672 HydrophobicContact CG-CE2 4.19Å; E587-F672 HydrophobicContact CG-CG 4.31Å; E587-F672 HydrophobicContact CG-CZ 4.36Å; I589-F672 HydrophobicContact CD1-CD2 3.84Å; I589-F672 HydrophobicContact CD1-CE2 4.18Å; C670-F672 HydrophobicContact CB-CD1 3.69Å; C670-F672 HydrophobicContact CB-CD2 4.46Å; C670-F672 HydrophobicContact CB-CE1 3.3Å; C670-F672 HydrophobicContact CB-CE2 4.15Å; C670-F672 HydrophobicContact CB-CG 4.26Å; C670-F672 HydrophobicContact CB-CZ 3.56Å; C670-F672 PolarHBondContact O-N 2.69Å; F672-Q674 VanDerWaalsContact C-N 3.29Å
673E86Confident88.1Confident17 Ų1752.6 Ų52.68%0.07929%0.291CS..THydrogen-bonded Turntrans-79.9-11.4172.7-68.2-178.2114.200112.2I589 K593 L594 Y598 L618 L669 C670I589-E673 HydrophobicContact CD1-CG 4.12Å; K593-E673 IonicContact NZ-OE1 3.63Å; K593-E673 PolarHBondContact NZ-OE1 2.69Å; K593-E673 IonicContact NZ-OE2 3.11Å; L594-E673 HydrophobicContact CD1-CB 4.47Å; L594-E673 WeakPolarHBondContact CD1-O 3.28Å; L594-E673 HydrophobicContact CD2-CB 3.81Å; L594-E673 HydrophobicContact CD2-CG 4.28Å; Y598-E673 PolarHBondContact OH-O 3.28Å; L618-E673 WeakPolarHBondContact CD1-O 3.49Å; L669-E673 WeakPolarHBondContact CA-OE2 3.4Å; L669-E673 HydrophobicContact CB-CB 4.13Å; C670-E673 HydrophobicContact CB-CG 4.2Å; C670-E673 PolarHBondContact N-OE2 2.81Å; C670-E673 WeakPolarHBondContact O-CB 3.5Å; C670-E673 PolarHBondContact O-N 3.29Å
674Q92.2Very high88.2Confident15 Ų1553.9 Ų53.97%0.0730%0.301CS..SBendtrans-87.1126.6-179.4-69.4-175.347.700112.3L669 C670 F672L669-Q674 HydrophobicContact CB-CG 4.34Å; L669-Q674 PolarHBondContact O-NE2 3.36Å; C670-Q674 PolarHBondContact O-N 3.44Å; F672-Q674 VanDerWaalsContact C-N 3.29Å
675V95Very high88.5Confident0 Ų054.1 Ų54.10%030%0.302CS..EExtended strand (participates in β ladder)trans-57.7133.7175.2172.70000110.3Y598 V609 L618 A620 L657 M660 H661 D677 I678Y598-V675 HydrophobicContact CE2-CG2 3.76Å; V609-V675 HydrophobicContact CG1-CG2 4.2Å; V609-V675 HydrophobicContact CG2-CG2 4.1Å; L618-V675 HydrophobicContact CB-CG2 4.25Å; L618-V675 CarbonylContact O-C 3.59Å; L618-V675 WeakPolarHBondContact O-CA 3.25Å; A620-V675 HydrophobicContact CB-CG1 3.8Å; A620-V675 HydrophobicContact CB-CG2 3.96Å; L657-V675 HydrophobicContact CD1-CG1 4.32Å; M660-V675 HydrophobicContact CE-CB 4.01Å; M660-V675 HydrophobicContact CE-CG1 4.23Å; M660-V675 HydrophobicContact CE-CG2 4.06Å; H661-V675 PolarHBondContact NE2-O 3.46Å; V675-D677 WeakPolarHBondContact CG1-O 3.3Å; V675-I678 HydrophobicContact CG1-CG2 3.84Å
676K94.2Very high88.3Confident87 Ų8749.1 Ų49.138%0.37828%0.283SS..EExtended strand (participates in β ladder)trans-99.7-25.6-176.8-63.4-58.9179.8-169.70114.5C617 L618 S671 L718C617-K676 HydrophobicContact CB-CB 4.27Å; C617-K676 HydrophobicContact CB-CG 3.59Å; L618-K676 PolarHBondContact O-N 2.92Å; S671-K676 PolarHBondContact O-NZ 3.42Å; K676-L718 HydrophobicContact CB-CD1 3.85Å; K676-L718 HydrophobicContact CB-CD2 3.88Å
677D95.5Very high87.8Confident28 Ų2842 Ų4215%0.1526%0.255CS..EExtended strand (participates in β ladder)trans-146.6154.8174.8-165.36.9000110.2V619 A620 V675 M714 S717 L718V619-D677 WeakPolarHBondContact CA-O 3.47Å; V619-D677 HydrophobicContact CG1-CB 4.49Å; A620-D677 PolarHBondContact N-O 2.65Å; V675-D677 WeakPolarHBondContact CG1-O 3.3Å; D677-M714 HydrophobicContact CB-CB 4.25Å; D677-M714 HydrophobicContact CB-CG 4.33Å; D677-M714 HydrophobicContact CB-SD 4.43Å; D677-S717 PolarHBondContact OD2-OG 2.68Å; D677-S717 VanDerWaalsContact OD2-OG 3.11Å; D677-L718 HydrophobicContact CB-CD1 3.83Å; D677-L718 HydrophobicContact CB-CD2 4.28Å; D677-L718 HydrophobicContact CB-CG 4.15Å
678I96.9Very high87.8Confident1 Ų146.6 Ų46.61%0.00527%0.269CS..EExtended strand (participates in β ladder)trans-130.5147.5-179.959.3171.9000112.8A620 V622 K653 I656 L657 M660 V675 I680A620-I678 HydrophobicContact CB-CG2 4.24Å; A620-I678 CarbonylContact O-C 3.49Å; A620-I678 VanDerWaalsContact O-CA 3.23Å; A620-I678 WeakPolarHBondContact O-CA 3.26Å; V622-I678 HydrophobicContact CG2-CB 4.32Å; V622-I678 HydrophobicContact CG2-CG2 4.09Å; K653-I678 VanDerWaalsContact CE-O 3.28Å; K653-I678 WeakPolarHBondContact CE-O 3.46Å; K653-I678 PolarHBondContact NZ-O 3.45Å; I656-I678 HydrophobicContact CB-CD1 3.73Å; I656-I678 HydrophobicContact CG2-CD1 3.63Å; L657-I678 HydrophobicContact CB-CD1 4.26Å; L657-I678 HydrophobicContact CD1-CG2 4.01Å; M660-I678 HydrophobicContact CE-CG2 4.26Å; M660-I678 HydrophobicContact SD-CG2 3.95Å; V675-I678 HydrophobicContact CG1-CG2 3.84Å; I678-I680 HydrophobicContact CD1-CG1 4.43Å
679Y96.6Very high88.2Confident52 Ų5245.5 Ų45.520%0.20425%0.249CC..EExtended strand (participates in β ladder)trans-111.1125.1165.3177.5-99.2000109.2A620 V621 V622 N647 S681 F707 Q710 M714A620-Y679 PolarHBondContact O-N 3.09Å; V621-Y679 CarbonylContact C-O 3.55Å; V621-Y679 WeakPolarHBondContact CA-O 3.21Å; V621-Y679 HydrophobicContact CG1-CD1 4.03Å; V621-Y679 HydrophobicContact CG2-CD1 4.46Å; V622-Y679 PolarHBondContact N-O 3.5Å; N647-Y679 HydrophobicContact CB-CE2 4.46Å; N647-Y679 VanDerWaalsContact CG-CE2 3.5Å; N647-Y679 VanDerWaalsContact ND2-CE2 3.32Å; N647-Y679 WeakPolarHBondContact ND2-CE2 3.27Å; N647-Y679 WeakPolarHBondContact OD1-CD2 3.44Å; Y679-S681 PolarHBondContact O-N 3.05Å; Y679-F707 HydrophobicContact CD1-CD1 4.2Å; Y679-F707 HydrophobicContact CD1-CE1 4.35Å; Y679-F707 HydrophobicContact CE1-CD1 4.06Å; Y679-F707 AromaticContact CE1-CE1 3.95Å; Y679-F707 HydrophobicContact CE1-CE1 3.95Å; Y679-Q710 HydrophobicContact CD1-CB 4.22Å; Y679-Q710 HydrophobicContact CD1-CG 4Å; Y679-Q710 HydrophobicContact CD2-CB 3.95Å; Y679-Q710 HydrophobicContact CD2-CG 3.66Å; Y679-Q710 HydrophobicContact CE1-CG 3.86Å; Y679-Q710 HydrophobicContact CE2-CB 4.31Å; Y679-Q710 HydrophobicContact CE2-CG 3.5Å; Y679-Q710 VanDerWaalsContact CE2-CG 3.5Å; Y679-Q710 HydrophobicContact CG-CB 3.9Å; Y679-Q710 HydrophobicContact CG-CG 3.91Å; Y679-M714 PolarHBondContact N-SD 2.83Å
680I96Very high88.4Confident2 Ų249 Ų491%0.0127%0.267CS..EExtended strand (participates in β ladder)trans-91.1102.6-179.3-53.9172.8000108.2V622 P624 L646 N647 V652 K653 I656 I678V622-I680 CarbonylContact O-C 3.21Å; V622-I680 WeakPolarHBondContact O-CA 3.4Å; P624-I680 HydrophobicContact CB-CG2 4.28Å; P624-I680 HydrophobicContact CG-CG2 3.79Å; L646-I680 HydrophobicContact CB-CB 4.28Å; L646-I680 HydrophobicContact CB-CD1 4.14Å; L646-I680 HydrophobicContact CB-CG2 3.87Å; L646-I680 HydrophobicContact CD1-CG2 3.93Å; N647-I680 PolarHBondContact ND2-O 3.42Å; N647-I680 PolarHBondContact OD1-N 3.38Å; V652-I680 HydrophobicContact CG1-CD1 3.86Å; K653-I680 HydrophobicContact CG-CD1 3.74Å; K653-I680 HydrophobicContact CG-CG1 4.26Å; I656-I680 HydrophobicContact CD1-CD1 3.86Å; I656-I680 HydrophobicContact CD1-CG1 4.3Å; I678-I680 HydrophobicContact CD1-CG1 4.43Å
681S93.1Very high88.8Confident4 Ų446.2 Ų46.23%0.02825%0.249CC..  trans-75.6127.7176.7-172.30000110.7V622 P624 Y679 E683V622-S681 PolarHBondContact O-N 3.25Å; P624-S681 WeakPolarHBondContact CD-O 3.45Å; Y679-S681 PolarHBondContact O-N 3.05Å; S681-E683 VanDerWaalsContact C-N 3.26Å; S681-E683 PolarHBondContact OG-N 3.12Å; S681-E683 PolarHBondContact OG-O 3.27Å
682S87.7Confident88.6Confident106 Ų10642.5 Ų42.574%0.74122%0.222SC*.SBendtrans-73.5-22.316856.30000112.4
683E89.1Confident88.2Confident88 Ų8839.8 Ų39.841%0.41121%0.21SC..SBendtrans-97.2125.7179.5-168.4-178.7164.900110.1S681 N689S681-E683 VanDerWaalsContact C-N 3.26Å; S681-E683 PolarHBondContact OG-N 3.12Å; S681-E683 PolarHBondContact OG-O 3.27Å; E683-N689 WeakPolarHBondContact OE1-CB 3.26Å; E683-N689 PolarHBondContact OE1-ND2 3.36Å
684P90.7Very high87Confident62 Ų6239.9 Ų39.940%0.40321%0.212SC..PPolyproline II helixtrans-70.3154.8174.729.6-33.9000111.6V623 T686 N689V623-P684 HydrophobicContact CG1-CB 4.06Å; P684-T686 HydrophobicContact CB-CG2 4.29Å; P684-T686 HydrophobicContact CG-CG2 4Å; P684-T686 PolarHBondContact O-N 3.18Å; P684-N689 PolarHBondContact O-ND2 3.07Å
685F91.1Very high85.6Confident4 Ų441.5 Ų41.52%0.01822%0.223CC..PPolyproline II helixtrans-75.6123.6170-46.4-29.4000108.5Q606 F608 V621 V623 L691 L692 L703 F707Q606-F685 HydrophobicContact CB-CD2 3.9Å; Q606-F685 HydrophobicContact CB-CE2 4.1Å; Q606-F685 PolarHBondContact NE2-O 2.9Å; F608-F685 HydrophobicContact CB-CE2 3.96Å; F608-F685 HydrophobicContact CB-CZ 4.06Å; V621-F685 HydrophobicContact CB-CZ 4.31Å; V621-F685 HydrophobicContact CG1-CE1 4.05Å; V621-F685 HydrophobicContact CG1-CZ 3.84Å; V623-F685 HydrophobicContact CG2-CD1 4.02Å; V623-F685 HydrophobicContact CG2-CD2 4.48Å; V623-F685 HydrophobicContact CG2-CE1 3.76Å; V623-F685 HydrophobicContact CG2-CE2 4.27Å; V623-F685 HydrophobicContact CG2-CG 4.36Å; V623-F685 HydrophobicContact CG2-CZ 3.9Å; F685-L691 HydrophobicContact CB-CB 4.01Å; F685-L691 HydrophobicContact CD1-CD1 3.81Å; F685-L692 HydrophobicContact CB-CD1 4.39Å; F685-L692 HydrophobicContact CB-CD2 3.79Å; F685-L692 HydrophobicContact CB-CG 3.87Å; F685-L692 WeakPolarHBondContact O-CD1 3.36Å; F685-L703 HydrophobicContact CD1-CD2 3.75Å; F685-L703 HydrophobicContact CD2-CD2 4.22Å; F685-L703 HydrophobicContact CE1-CD2 3.77Å; F685-L703 HydrophobicContact CE2-CD2 4.23Å; F685-L703 HydrophobicContact CG-CD2 4Å; F685-L703 HydrophobicContact CZ-CD2 4.01Å; F685-F707 HydrophobicContact CD1-CE2 4.24Å; F685-F707 HydrophobicContact CD1-CZ 4.48Å; F685-F707 AromaticContact CE1-CE2 3.55Å; F685-F707 HydrophobicContact CE1-CE2 3.55Å; F685-F707 AromaticContact CE1-CZ 3.81Å; F685-F707 HydrophobicContact CE1-CZ 3.81Å; F685-F707 HydrophobicContact CZ-CE2 4.32Å
686T85.8Confident84.3Confident36 Ų3645.5 Ų45.522%0.22124%0.244CC..  trans-134.6172.4-179.886.30000111.9P684 E688 N689 L691 L692P684-T686 HydrophobicContact CB-CG2 4.29Å; P684-T686 HydrophobicContact CG-CG2 4Å; P684-T686 PolarHBondContact O-N 3.18Å; T686-E688 WeakPolarHBondContact CB-OE2 3.3Å; T686-E688 PolarHBondContact OG1-N 3.28Å; T686-E688 PolarHBondContact OG1-OE2 2.93Å; T686-N689 WeakPolarHBondContact CA-OD1 3.29Å; T686-N689 PolarHBondContact N-OD1 3.25Å; T686-N689 PolarHBondContact O-OD1 2.95Å; T686-N689 PolarHBondContact OG1-N 3.49Å; T686-N689 PolarHBondContact OG1-OD1 2.89Å; T686-L691 PolarHBondContact O-N 2.87Å; T686-L691 VanDerWaalsContact O-N 3.12Å; T686-L692 PolarHBondContact O-N 3.26Å
687V74Confident83.2Confident36 Ų3645.3 Ų45.322%0.21824%0.243CC..THydrogen-bonded Turntrans-74.6-35.3173.7-175.90000109.5N690 L692 T693 L696V687-N690 WeakPolarHBondContact O-CA 3.31Å; V687-N690 PolarHBondContact O-N 3.31Å; V687-L692 HydrophobicContact CG2-CB 4.3Å; V687-T693 WeakPolarHBondContact CG2-O 3.21Å; V687-L696 HydrophobicContact CG2-CD2 4Å
688E78.6Confident82.6Confident167 Ų16745.5 Ų45.578%0.7825%0.247SC*.THydrogen-bonded Turntrans-65.2-39.9-178.7-58.478-172.700112.9T686 N690T686-E688 WeakPolarHBondContact CB-OE2 3.3Å; T686-E688 PolarHBondContact OG1-N 3.28Å; T686-E688 PolarHBondContact OG1-OE2 2.93Å; E688-N690 PolarHBondContact O-N 3.03Å
689N86.7Confident81.6Confident37 Ų3747 Ų4720%0.19825%0.254CS..THydrogen-bonded Turntrans-85.710.7172.868.29.1000113.4E683 P684 T686 L691E683-N689 WeakPolarHBondContact OE1-CB 3.26Å; E683-N689 PolarHBondContact OE1-ND2 3.36Å; P684-N689 PolarHBondContact O-ND2 3.07Å; T686-N689 WeakPolarHBondContact CA-OD1 3.29Å; T686-N689 PolarHBondContact N-OD1 3.25Å; T686-N689 PolarHBondContact O-OD1 2.95Å; T686-N689 PolarHBondContact OG1-N 3.49Å; T686-N689 PolarHBondContact OG1-OD1 2.89Å; N689-L691 PolarHBondContact O-N 3.36Å; N689-L691 WeakPolarHBondContact OD1-CB 3.36Å; N689-L691 VanDerWaalsContact OD1-CG 3.31Å; N689-L691 WeakPolarHBondContact OD1-CG 3.44Å; N689-L691 PolarHBondContact OD1-N 3.33Å
690N84.3Confident81.2Confident84 Ų8445.6 Ų45.645%0.44925%0.248SC..THydrogen-bonded Turntrans61.319.8176.2-16632.1000114.4V687 E688 K699V687-N690 WeakPolarHBondContact O-CA 3.31Å; V687-N690 PolarHBondContact O-N 3.31Å; E688-N690 PolarHBondContact O-N 3.03Å; N690-K699 PolarHBondContact OD1-NZ 3.44Å
691L86.9Confident80.5Confident1 Ų148.6 Ų48.61%0.00527%0.267CS..SBendtrans-89.8-22.9178.3-61.6-176.3000113F685 T686 N689 K699 V702 L703 H706 F707F685-L691 HydrophobicContact CB-CB 4.01Å; F685-L691 HydrophobicContact CD1-CD1 3.81Å; T686-L691 PolarHBondContact O-N 2.87Å; T686-L691 VanDerWaalsContact O-N 3.12Å; N689-L691 PolarHBondContact O-N 3.36Å; N689-L691 WeakPolarHBondContact OD1-CB 3.36Å; N689-L691 VanDerWaalsContact OD1-CG 3.31Å; N689-L691 WeakPolarHBondContact OD1-CG 3.44Å; N689-L691 PolarHBondContact OD1-N 3.33Å; L691-K699 PolarHBondContact O-N 2.9Å; L691-V702 HydrophobicContact CD2-CG1 4.12Å; L691-L703 HydrophobicContact CB-CD2 3.99Å; L691-L703 HydrophobicContact CB-CG 4.49Å; L691-L703 HydrophobicContact CD1-CD2 4.14Å; L691-L703 HydrophobicContact CD2-CD2 4.07Å; L691-L703 HydrophobicContact CD2-CG 4.5Å; L691-L703 HydrophobicContact CG-CD2 4.29Å; L691-H706 HydrophobicContact CD2-CB 3.94Å; L691-F707 HydrophobicContact CD1-CE2 4.26Å; L691-F707 HydrophobicContact CD1-CZ 4.49Å
692L80.6Confident80.2Confident9 Ų950.7 Ų50.75%0.04728%0.28CS..BIsolated β-bridgetrans-109.7153.4172.2-60.3-175.8000111.9F685 T686 V687 L696 K697 K699F685-L692 HydrophobicContact CB-CD1 4.39Å; F685-L692 HydrophobicContact CB-CD2 3.79Å; F685-L692 HydrophobicContact CB-CG 3.87Å; F685-L692 WeakPolarHBondContact O-CD1 3.36Å; T686-L692 PolarHBondContact O-N 3.26Å; V687-L692 HydrophobicContact CG2-CB 4.3Å; L692-L696 HydrophobicContact CD1-CD2 4.25Å; L692-K697 CarbonylContact C-O 3.43Å; L692-K697 WeakPolarHBondContact CA-O 3.48Å; L692-K699 VanDerWaalsContact O-CE 3.29Å; L692-K699 WeakPolarHBondContact O-CE 2.96Å
693T71.3Confident80.3Confident0 Ų045.6 Ų45.60%024%0.244CC..  trans-67.9161.916666.70000110.1T301 V687 T695 L696 K697 K699T301-T693 HydrophobicContact CG2-CG2 3.67Å; V687-T693 WeakPolarHBondContact CG2-O 3.21Å; T693-T695 PolarHBondContact O-N 2.96Å; T693-T695 PolarHBondContact OG1-N 3.5Å; T693-T695 PolarHBondContact OG1-OG1 3.1Å; T693-L696 WeakPolarHBondContact O-CA 3.45Å; T693-L696 PolarHBondContact O-N 3.45Å; T693-L696 PolarHBondContact OG1-N 3.1Å; T693-K697 HydrophobicContact CG2-CB 4.13Å; T693-K697 WeakPolarHBondContact CG2-O 3.32Å; T693-K697 PolarHBondContact N-O 2.73Å; T693-K697 WeakPolarHBondContact OG1-CB 3.33Å; T693-K697 PolarHBondContact OG1-N 3.44Å; T693-K697 PolarHBondContact OG1-O 2.9Å; T693-K699 HydrophobicContact CG2-CG 3.86Å
694P61.5Low80.3Confident19 Ų1946.9 Ų46.912%0.12325%0.245CC..THydrogen-bonded Turntrans-51.4-28.2168.9-29.934.5000115.3Y183 T185 L696Y183-P694 HydrophobicContact CD2-CB 4Å; Y183-P694 HydrophobicContact CE2-CB 3.38Å; Y183-P694 HydrophobicContact CE2-CG 4.09Å; T185-P694 WeakPolarHBondContact CB-O 3.32Å; T185-P694 VanDerWaalsContact O-CB 3.26Å; T185-P694 WeakPolarHBondContact O-CB 3.24Å; T185-P694 WeakPolarHBondContact O-CG 3.29Å; T185-P694 WeakPolarHBondContact OG1-CA 3.49Å; T185-P694 VanDerWaalsContact OG1-CB 3.24Å; T185-P694 WeakPolarHBondContact OG1-CB 3.49Å; T185-P694 PolarHBondContact OG1-O 2.9Å; P694-L696 VanDerWaalsContact C-N 3.31Å
695T62.1Low80.2Confident48 Ų4849.4 Ų49.429%0.29426%0.255SS..THydrogen-bonded Turntrans-90.715.3176.550.10000113.3S299 T693 K697S299-T695 PolarHBondContact OG-OG1 2.89Å; S299-T695 VanDerWaalsContact OG-OG1 3.11Å; T693-T695 PolarHBondContact O-N 2.96Å; T693-T695 PolarHBondContact OG1-N 3.5Å; T693-T695 PolarHBondContact OG1-OG1 3.1Å; T695-K697 VanDerWaalsContact C-N 3.26Å; T695-K697 PolarHBondContact O-N 2.79Å
696L67.1Low80.3Confident85 Ų8553.6 Ų53.645%0.44528%0.275SS..SBendtrans64.918178.2-54.3171000115.5R388 V687 L692 T693 P694R388-L696 VanDerWaalsContact NH1-CD1 3.33Å; V687-L696 HydrophobicContact CG2-CD2 4Å; L692-L696 HydrophobicContact CD1-CD2 4.25Å; T693-L696 WeakPolarHBondContact O-CA 3.45Å; T693-L696 PolarHBondContact O-N 3.45Å; T693-L696 PolarHBondContact OG1-N 3.1Å; P694-L696 VanDerWaalsContact C-N 3.31Å
697K72.4Confident80.7Confident82 Ų8252 Ų5236%0.35727%0.265SS..  trans-84.5146.2173.4-58.3-169.4175.3-169.10110.6L692 T693 T695 K699L692-K697 CarbonylContact C-O 3.43Å; L692-K697 WeakPolarHBondContact CA-O 3.48Å; T693-K697 HydrophobicContact CG2-CB 4.13Å; T693-K697 WeakPolarHBondContact CG2-O 3.32Å; T693-K697 PolarHBondContact N-O 2.73Å; T693-K697 WeakPolarHBondContact OG1-CB 3.33Å; T693-K697 PolarHBondContact OG1-N 3.44Å; T693-K697 PolarHBondContact OG1-O 2.9Å; T695-K697 VanDerWaalsContact C-N 3.26Å; T695-K697 PolarHBondContact O-N 2.79Å; K697-K699 PolarHBondContact O-N 2.95Å
698S81.2Confident81.6Confident33 Ų3353 Ų5323%0.23127%0.273CS..BIsolated β-bridgetrans-65.5126.9179.1-66.80000112.4R700S698-R700 VanDerWaalsContact C-N 3.34Å; S698-R700 PolarHBondContact O-N 3.47Å; S698-R700 VanDerWaalsContact O-N 3.08Å
699K77.6Confident82.4Confident33 Ų3353.2 Ų53.214%0.14327%0.272CS..  trans-82.178.6170.6-68-172.6-175.5-179.60110N690 L691 L692 T693 K697 V702 L703N690-K699 PolarHBondContact OD1-NZ 3.44Å; L691-K699 PolarHBondContact O-N 2.9Å; L692-K699 VanDerWaalsContact O-CE 3.29Å; L692-K699 WeakPolarHBondContact O-CE 2.96Å; T693-K699 HydrophobicContact CG2-CG 3.86Å; K697-K699 PolarHBondContact O-N 2.95Å; K699-V702 HydrophobicContact CB-CB 3.92Å; K699-V702 HydrophobicContact CB-CG2 3.89Å; K699-V702 HydrophobicContact CD-CG2 4.14Å; K699-V702 WeakPolarHBondContact O-CA 3.35Å; K699-V702 WeakPolarHBondContact O-CB 3.41Å; K699-V702 PolarHBondContact O-N 2.99Å; K699-L703 PolarHBondContact O-N 2.77Å
700R87.1Confident82.7Confident22 Ų2253.9 Ų53.98%0.08327%0.274CS..Hα-helixtrans-49.8-43.8-172.1-53.8-17968.969.911.6114.6P591 E595 F608 V609 S698 V702 L703 R704P591-R700 VanDerWaalsContact CG-CZ 3.41Å; P591-R700 VanDerWaalsContact CG-NH2 3.25Å; E595-R700 IonicContact OE1-CZ 3Å; E595-R700 IonicContact OE1-NH1 3.9Å; E595-R700 PolarHBondContact OE1-NH1 3.44Å; E595-R700 IonicContact OE1-NH2 2.76Å; E595-R700 IonicContact OE2-NH1 3.24Å; E595-R700 PolarHBondContact OE2-NH1 3.01Å; F608-R700 HydrophobicContact CE2-CB 3.99Å; F608-R700 HydrophobicContact CE2-CG 4.22Å; V609-R700 PolarHBondContact O-NH2 3.5Å; S698-R700 VanDerWaalsContact C-N 3.34Å; S698-R700 PolarHBondContact O-N 3.47Å; S698-R700 VanDerWaalsContact O-N 3.08Å; R700-V702 PolarHBondContact O-N 3.22Å; R700-L703 PolarHBondContact O-N 2.66Å; R700-R704 WeakPolarHBondContact O-CB 3.48Å; R700-R704 PolarHBondContact O-N 3.06Å
701P82.2Confident83.2Confident64 Ų6450.4 Ų50.442%0.41626%0.255SS..Hα-helixtrans-65.1-38.4176.4-2234.7000113.2T302 N705T302-P701 HydrophobicContact CG2-CG 4.37Å; P701-N705 WeakPolarHBondContact O-CB 3.31Å; P701-N705 VanDerWaalsContact O-CG 3.25Å; P701-N705 PolarHBondContact O-N 3.29Å; P701-N705 PolarHBondContact O-ND2 2.99Å
702V85.6Confident83.4Confident48 Ų4853.1 Ų53.129%0.29127%0.274SS..Hα-helixtrans-69.5-43.9178.1-174.60000110.4L691 K699 R700 N705 H706L691-V702 HydrophobicContact CD2-CG1 4.12Å; K699-V702 HydrophobicContact CB-CB 3.92Å; K699-V702 HydrophobicContact CB-CG2 3.89Å; K699-V702 HydrophobicContact CD-CG2 4.14Å; K699-V702 WeakPolarHBondContact O-CA 3.35Å; K699-V702 WeakPolarHBondContact O-CB 3.41Å; K699-V702 PolarHBondContact O-N 2.99Å; R700-V702 PolarHBondContact O-N 3.22Å; V702-N705 PolarHBondContact O-N 3.41Å; V702-H706 VanDerWaalsContact O-CB 3.26Å; V702-H706 WeakPolarHBondContact O-CB 3.41Å; V702-H706 PolarHBondContact O-N 3.43Å
703L90.4Very high84Confident0 Ų059.9 Ų59.90%030%0.303CS..Hα-helixtrans-58.9-46.5173.9-77.8162.9000111.8F608 F685 L691 K699 R700 N705 H706 F707F608-L703 HydrophobicContact CB-CD1 4.28Å; F608-L703 HydrophobicContact CD1-CB 3.95Å; F608-L703 HydrophobicContact CD2-CB 4.27Å; F608-L703 HydrophobicContact CD2-CD1 3.97Å; F608-L703 HydrophobicContact CE1-CB 3.9Å; F608-L703 HydrophobicContact CE2-CB 4.23Å; F608-L703 HydrophobicContact CG-CB 4.13Å; F608-L703 HydrophobicContact CG-CD1 4.07Å; F608-L703 HydrophobicContact CZ-CB 4.04Å; F685-L703 HydrophobicContact CD1-CD2 3.75Å; F685-L703 HydrophobicContact CD2-CD2 4.22Å; F685-L703 HydrophobicContact CE1-CD2 3.77Å; F685-L703 HydrophobicContact CE2-CD2 4.23Å; F685-L703 HydrophobicContact CG-CD2 4Å; F685-L703 HydrophobicContact CZ-CD2 4.01Å; L691-L703 HydrophobicContact CB-CD2 3.99Å; L691-L703 HydrophobicContact CB-CG 4.49Å; L691-L703 HydrophobicContact CD1-CD2 4.14Å; L691-L703 HydrophobicContact CD2-CD2 4.07Å; L691-L703 HydrophobicContact CD2-CG 4.5Å; L691-L703 HydrophobicContact CG-CD2 4.29Å; K699-L703 PolarHBondContact O-N 2.77Å; R700-L703 PolarHBondContact O-N 2.66Å; L703-N705 VanDerWaalsContact C-N 3.31Å; L703-N705 PolarHBondContact O-N 3.38Å; L703-H706 PolarHBondContact O-N 3.17Å; L703-F707 HydrophobicContact CD2-CD2 4.1Å; L703-F707 HydrophobicContact CD2-CE2 3.73Å; L703-F707 WeakPolarHBondContact O-CD2 3.39Å; L703-F707 PolarHBondContact O-N 3.05Å
704R88.4Confident85.1Confident114 Ų11460.1 Ų60.143%0.4331%0.305SS..Hα-helixtrans-56.2-46.2175.1-177.8-171.8180173.55.7111.4F608 D612 R700 S708F608-R704 HydrophobicContact CZ-CB 4.32Å; D612-R704 IonicContact OD2-CZ 3.83Å; D612-R704 IonicContact OD2-NH2 3.24Å; D612-R704 PolarHBondContact OD2-NH2 3.46Å; R700-R704 WeakPolarHBondContact O-CB 3.48Å; R700-R704 PolarHBondContact O-N 3.06Å; R704-S708 VanDerWaalsContact O-CA 3.27Å; R704-S708 WeakPolarHBondContact O-CA 3.33Å; R704-S708 WeakPolarHBondContact O-CB 3.49Å; R704-S708 PolarHBondContact O-N 2.91Å
705N89.2Confident86.5Confident115 Ų11559.8 Ų59.862%0.61530%0.301SS*.Hα-helixtrans-69.2-44.3-179.1-71.5-14.7000111.9P701 V702 L703 S708P701-N705 WeakPolarHBondContact O-CB 3.31Å; P701-N705 VanDerWaalsContact O-CG 3.25Å; P701-N705 PolarHBondContact O-N 3.29Å; P701-N705 PolarHBondContact O-ND2 2.99Å; V702-N705 PolarHBondContact O-N 3.41Å; L703-N705 VanDerWaalsContact C-N 3.31Å; L703-N705 PolarHBondContact O-N 3.38Å; N705-S708 VanDerWaalsContact O-CB 3.29Å; N705-S708 WeakPolarHBondContact O-CB 3.4Å; N705-S708 PolarHBondContact O-N 3.16Å; N705-S708 PolarHBondContact O-OG 3.28Å
706H93.1Very high87.9Confident92 Ų9263.9 Ų63.943%0.42632%0.316SS..Hα-helixtrans-61.6-44.3179.4-17592.3000111.8L691 V702 L703L691-H706 HydrophobicContact CD2-CB 3.94Å; V702-H706 VanDerWaalsContact O-CB 3.26Å; V702-H706 WeakPolarHBondContact O-CB 3.41Å; V702-H706 PolarHBondContact O-N 3.43Å; L703-H706 PolarHBondContact O-N 3.17Å
707F95Very high88.8Confident4 Ų463.5 Ų63.52%0.01832%0.321CS..THydrogen-bonded Turntrans-95.416179.3-64.7-69.6000113.9V621 Y679 F685 L691 L703 K709 Q710 I711V621-F707 HydrophobicContact CB-CD2 4.48Å; V621-F707 HydrophobicContact CG1-CD1 4.24Å; V621-F707 HydrophobicContact CG1-CD2 4.15Å; V621-F707 HydrophobicContact CG1-CE1 4.07Å; V621-F707 HydrophobicContact CG1-CE2 3.98Å; V621-F707 HydrophobicContact CG1-CG 4.29Å; V621-F707 HydrophobicContact CG1-CZ 3.94Å; V621-F707 HydrophobicContact CG2-CB 3.94Å; V621-F707 HydrophobicContact CG2-CD1 4.3Å; V621-F707 HydrophobicContact CG2-CD2 4.07Å; V621-F707 HydrophobicContact CG2-CG 3.85Å; Y679-F707 HydrophobicContact CD1-CD1 4.2Å; Y679-F707 HydrophobicContact CD1-CE1 4.35Å; Y679-F707 HydrophobicContact CE1-CD1 4.06Å; Y679-F707 AromaticContact CE1-CE1 3.95Å; Y679-F707 HydrophobicContact CE1-CE1 3.95Å; F685-F707 HydrophobicContact CD1-CE2 4.24Å; F685-F707 HydrophobicContact CD1-CZ 4.48Å; F685-F707 AromaticContact CE1-CE2 3.55Å; F685-F707 HydrophobicContact CE1-CE2 3.55Å; F685-F707 AromaticContact CE1-CZ 3.81Å; F685-F707 HydrophobicContact CE1-CZ 3.81Å; F685-F707 HydrophobicContact CZ-CE2 4.32Å; L691-F707 HydrophobicContact CD1-CE2 4.26Å; L691-F707 HydrophobicContact CD1-CZ 4.49Å; L703-F707 HydrophobicContact CD2-CD2 4.1Å; L703-F707 HydrophobicContact CD2-CE2 3.73Å; L703-F707 WeakPolarHBondContact O-CD2 3.39Å; L703-F707 PolarHBondContact O-N 3.05Å; F707-K709 VanDerWaalsContact C-N 3.29Å; F707-K709 PolarHBondContact O-N 3.39Å; F707-Q710 PolarHBondContact O-N 3.06Å; F707-Q710 VanDerWaalsContact O-N 3.08Å; F707-Q710 PolarHBondContact O-OE1 3.38Å; F707-I711 HydrophobicContact CB-CD1 4.15Å; F707-I711 HydrophobicContact CB-CG1 4.35Å; F707-I711 WeakPolarHBondContact O-CB 3.42Å; F707-I711 VanDerWaalsContact O-CG1 3.31Å; F707-I711 WeakPolarHBondContact O-CG1 3.4Å; F707-I711 PolarHBondContact O-N 3.13Å
708S92.6Very high89.5Confident56 Ų5663 Ų6339%0.39232%0.322SS..Hα-helixtrans-55.8-40.2-173.353.40000113.7R704 N705 S712R704-S708 VanDerWaalsContact O-CA 3.27Å; R704-S708 WeakPolarHBondContact O-CA 3.33Å; R704-S708 WeakPolarHBondContact O-CB 3.49Å; R704-S708 PolarHBondContact O-N 2.91Å; N705-S708 VanDerWaalsContact O-CB 3.29Å; N705-S708 WeakPolarHBondContact O-CB 3.4Å; N705-S708 PolarHBondContact O-N 3.16Å; N705-S708 PolarHBondContact O-OG 3.28Å; S708-S712 WeakPolarHBondContact O-CB 3.18Å; S708-S712 PolarHBondContact O-N 3.42Å; S708-S712 PolarHBondContact O-OG 3.23Å
709K94.3Very high88.7Confident171 Ų17168 Ų6874%0.74336%0.357SS*.Hα-helixtrans-66.1-44.1177.4-66.7-178-178.6177.50111.8F707 S712 K713F707-K709 VanDerWaalsContact C-N 3.29Å; F707-K709 PolarHBondContact O-N 3.39Å; K709-S712 PolarHBondContact O-N 3.19Å; K709-K713 WeakPolarHBondContact O-CB 3.49Å; K709-K713 PolarHBondContact O-N 3.37Å
710Q94.6Very high89.2Confident52 Ų5269.8 Ų69.824%0.24337%0.368CS..Hα-helixtrans-66.9-43.7179.5-65.977.12.800110.8Y679 F707 K713 M714Y679-Q710 HydrophobicContact CD1-CB 4.22Å; Y679-Q710 HydrophobicContact CD1-CG 4Å; Y679-Q710 HydrophobicContact CD2-CB 3.95Å; Y679-Q710 HydrophobicContact CD2-CG 3.66Å; Y679-Q710 HydrophobicContact CE1-CG 3.86Å; Y679-Q710 HydrophobicContact CE2-CB 4.31Å; Y679-Q710 HydrophobicContact CE2-CG 3.5Å; Y679-Q710 VanDerWaalsContact CE2-CG 3.5Å; Y679-Q710 HydrophobicContact CG-CB 3.9Å; Y679-Q710 HydrophobicContact CG-CG 3.91Å; F707-Q710 PolarHBondContact O-N 3.06Å; F707-Q710 VanDerWaalsContact O-N 3.08Å; F707-Q710 PolarHBondContact O-OE1 3.38Å; Q710-K713 PolarHBondContact O-N 2.93Å; Q710-M714 WeakPolarHBondContact O-CG 3.27Å; Q710-M714 PolarHBondContact O-N 3.19Å
711I94.1Very high89.3Confident10 Ų1072.3 Ų72.35%0.05138%0.383CS..Hα-helixtrans-59.6-46.5175-70.1167.1000110.8F608 H610 V619 F707 K713 M714 Y715F608-I711 HydrophobicContact CE1-CD1 4.21Å; H610-I711 HydrophobicContact CB-CD1 4.41Å; H610-I711 VanDerWaalsContact CD2-CG2 3.47Å; H610-I711 WeakPolarHBondContact CD2-CG2 3.36Å; V619-I711 HydrophobicContact CG2-CG2 4.26Å; F707-I711 HydrophobicContact CB-CD1 4.15Å; F707-I711 HydrophobicContact CB-CG1 4.35Å; F707-I711 WeakPolarHBondContact O-CB 3.42Å; F707-I711 VanDerWaalsContact O-CG1 3.31Å; F707-I711 WeakPolarHBondContact O-CG1 3.4Å; F707-I711 PolarHBondContact O-N 3.13Å; I711-K713 VanDerWaalsContact C-N 3.34Å; I711-K713 PolarHBondContact O-N 3.47Å; I711-M714 HydrophobicContact CG1-CE 4.1Å; I711-M714 PolarHBondContact O-N 2.74Å; I711-Y715 HydrophobicContact CG2-CD2 3.81Å; I711-Y715 HydrophobicContact CG2-CE2 3.69Å; I711-Y715 WeakPolarHBondContact O-CD2 3.43Å; I711-Y715 PolarHBondContact O-N 2.76Å
712S91.8Very high89.7Confident59 Ų5972.7 Ų72.741%0.41338%0.381SS..Hα-helixtrans-60.5-45.4177.9-56.90000111.1S708 K709 M714 Y715 E716S708-S712 WeakPolarHBondContact O-CB 3.18Å; S708-S712 PolarHBondContact O-N 3.42Å; S708-S712 PolarHBondContact O-OG 3.23Å; K709-S712 PolarHBondContact O-N 3.19Å; S712-M714 PolarHBondContact O-N 2.99Å; S712-Y715 PolarHBondContact O-N 3.04Å; S712-Y715 VanDerWaalsContact O-N 3.12Å; S712-E716 WeakPolarHBondContact O-CG 3.24Å; S712-E716 PolarHBondContact O-N 2.9Å
713K93.3Very high90Very high151 Ų15174.2 Ų74.266%0.65739%0.386SS*.Hα-helixtrans-61.9-40177.3-171.2178179.3-177.20113.2K709 Q710 I711 Y715 E716 S717K709-K713 WeakPolarHBondContact O-CB 3.49Å; K709-K713 PolarHBondContact O-N 3.37Å; Q710-K713 PolarHBondContact O-N 2.93Å; I711-K713 VanDerWaalsContact C-N 3.34Å; I711-K713 PolarHBondContact O-N 3.47Å; K713-Y715 VanDerWaalsContact C-N 3.31Å; K713-E716 PolarHBondContact O-N 3.48Å; K713-S717 PolarHBondContact O-N 3.45Å; K713-S717 PolarHBondContact O-OG 3.01Å
714M94.5Very high89.9Confident5 Ų578.8 Ų78.83%0.02541%0.41CS..Hα-helixtrans-65.1-35.6174.3-71.9-173.3-69.900111.8V619 D677 Y679 Q710 I711 S712 S717 L718V619-M714 HydrophobicContact CB-CB 4.26Å; V619-M714 HydrophobicContact CB-CE 3.83Å; V619-M714 HydrophobicContact CB-SD 4.04Å; V619-M714 HydrophobicContact CG1-CB 3.86Å; V619-M714 HydrophobicContact CG2-CE 3.86Å; D677-M714 HydrophobicContact CB-CB 4.25Å; D677-M714 HydrophobicContact CB-CG 4.33Å; D677-M714 HydrophobicContact CB-SD 4.43Å; Y679-M714 PolarHBondContact N-SD 2.83Å; Q710-M714 WeakPolarHBondContact O-CG 3.27Å; Q710-M714 PolarHBondContact O-N 3.19Å; I711-M714 HydrophobicContact CG1-CE 4.1Å; I711-M714 PolarHBondContact O-N 2.74Å; S712-M714 PolarHBondContact O-N 2.99Å; M714-S717 WeakPolarHBondContact CA-OG 3.46Å; M714-S717 PolarHBondContact O-OG 3.4Å; M714-L718 WeakPolarHBondContact O-CD1 3.25Å; M714-L718 WeakPolarHBondContact O-CG 3.49Å; M714-L718 PolarHBondContact O-N 3.42Å
715Y90.9Very high90Very high11 Ų1176.5 Ų76.54%0.04341%0.409CS..Hα-helixtrans-73.9-32.2175.1-79.6-53.5000113.4H610 G611 K615 C617 V619 I711 S712 K713 L718 S719H610-Y715 AromaticContact CD2-CE2 4Å; H610-Y715 PolarHBondContact O-OH 2.97Å; G611-Y715 WeakPolarHBondContact CA-OH 3.24Å; K615-Y715 HydrophobicContact CB-CD1 4.14Å; K615-Y715 HydrophobicContact CB-CE1 3.57Å; K615-Y715 HydrophobicContact CD-CD1 3.62Å; K615-Y715 HydrophobicContact CD-CD2 4.19Å; K615-Y715 HydrophobicContact CD-CE1 3.95Å; K615-Y715 HydrophobicContact CD-CE2 4.46Å; K615-Y715 HydrophobicContact CD-CG 3.77Å; K615-Y715 HydrophobicContact CG-CD1 3.81Å; K615-Y715 HydrophobicContact CG-CD2 4.09Å; K615-Y715 HydrophobicContact CG-CE1 3.59Å; K615-Y715 HydrophobicContact CG-CE2 3.86Å; K615-Y715 HydrophobicContact CG-CG 4.07Å; C617-Y715 WeakPolarHBondContact O-CE1 3.42Å; C617-Y715 PolarHBondContact O-OH 2.63Å; C617-Y715 VanDerWaalsContact O-OH 3.13Å; V619-Y715 HydrophobicContact CG1-CD1 4.07Å; V619-Y715 HydrophobicContact CG1-CE1 3.75Å; V619-Y715 HydrophobicContact CG2-CE1 4.41Å; V619-Y715 HydrophobicContact CG2-CE2 3.86Å; I711-Y715 HydrophobicContact CG2-CD2 3.81Å; I711-Y715 HydrophobicContact CG2-CE2 3.69Å; I711-Y715 WeakPolarHBondContact O-CD2 3.43Å; I711-Y715 PolarHBondContact O-N 2.76Å; S712-Y715 PolarHBondContact O-N 3.04Å; S712-Y715 VanDerWaalsContact O-N 3.12Å; K713-Y715 VanDerWaalsContact C-N 3.31Å; Y715-L718 PolarHBondContact O-N 3.23Å; Y715-S719 PolarHBondContact O-N 3.31Å; Y715-S719 VanDerWaalsContact O-N 3.1Å; Y715-S719 PolarHBondContact O-OG 3.19Å
716E90.2Very high90.1Very high134 Ų13473.7 Ų73.763%0.62639%0.394SS*.Hα-helixtrans-68.6-34.1174-73.5168.9-168.900112.4S712 K713 L718 S719S712-E716 WeakPolarHBondContact O-CG 3.24Å; S712-E716 PolarHBondContact O-N 2.9Å; K713-E716 PolarHBondContact O-N 3.48Å; E716-L718 VanDerWaalsContact C-N 3.28Å; E716-S719 WeakPolarHBondContact CA-OG 3.41Å; E716-S719 PolarHBondContact O-OG 3.22Å; E716-S719 VanDerWaalsContact O-OG 3.07Å
717S86.8Confident89.9Confident78 Ų7872.3 Ų72.355%0.54539%0.392SS..Hα-helixtrans-72.7-21.517554.40000113.4D677 K713 M714D677-S717 PolarHBondContact OD2-OG 2.68Å; D677-S717 VanDerWaalsContact OD2-OG 3.11Å; K713-S717 PolarHBondContact O-N 3.45Å; K713-S717 PolarHBondContact O-OG 3.01Å; M714-S717 WeakPolarHBondContact CA-OG 3.46Å; M714-S717 PolarHBondContact O-OG 3.4Å
718L85.8Confident89.4Confident71 Ų7178 Ų7837%0.37242%0.423SS..Hα-helixtrans-95.6-19-178.9-70.5172.7000113.8V619 K676 D677 M714 Y715 E716V619-L718 HydrophobicContact CG1-CD1 3.8Å; K676-L718 HydrophobicContact CB-CD1 3.85Å; K676-L718 HydrophobicContact CB-CD2 3.88Å; D677-L718 HydrophobicContact CB-CD1 3.83Å; D677-L718 HydrophobicContact CB-CD2 4.28Å; D677-L718 HydrophobicContact CB-CG 4.15Å; M714-L718 WeakPolarHBondContact O-CD1 3.25Å; M714-L718 WeakPolarHBondContact O-CG 3.49Å; M714-L718 PolarHBondContact O-N 3.42Å; Y715-L718 PolarHBondContact O-N 3.23Å; E716-L718 VanDerWaalsContact C-N 3.28Å
719S64.6Low89.2Confident138 Ų13880 Ų8097%0.96543%0.426SS*.  trans-85.2017359.70000111.4Y715 E716Y715-S719 PolarHBondContact O-N 3.31Å; Y715-S719 VanDerWaalsContact O-N 3.1Å; Y715-S719 PolarHBondContact O-OG 3.19Å; E716-S719 WeakPolarHBondContact CA-OG 3.41Å; E716-S719 PolarHBondContact O-OG 3.22Å; E716-S719 VanDerWaalsContact O-OG 3.07Å

Retrieved 719 of 719 residues in 269.1 ms (Link to these results)