A0A077Z565_TRITR Loading...

Kinesin-like protein

AlphaFold DB , UniProt , Accession A0A077Z565, Species TRITR (Trichuris trichiura, Whipworm), Gene n/a, Length 770 aa.

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Site Residue pLDDT pLDDT confidence pLDDT10 pLDDT10 confidence SASA SASA [Ų] SASA10 SASA10 [Ų] RSA RSA unformatted RSA10 RSA10 unformatted Surface Surface10 (not used) Disorder (not used) Disorder Sec. str. Secondary structure Isomer Phi (φ) Psi (ψ) Omega (ω) Chi 1 (χ1) Chi 2 (χ2) Chi 3 (χ3) Chi 4 (χ4) Chi 5 (χ5) Tau (τ) Contacts (colored by PAE) Contact details
1M42Very low82.5Confident223 Ų22356.2 Ų56.2100%1.09932%0.316SS*.  0133.80-69.9-72.4-166.700108.3
2P56.8Low83.7Confident65 Ų6552.8 Ų52.842%0.42230%0.295SS..PPolyproline II helixtrans-62.9138.5171.48.3-3000110.2R340P2-R340 HydrophobicContact CB-CB 4.49Å
3T72.4Confident84.7Confident116 Ų11649.2 Ų49.271%0.71228%0.276SS*.PPolyproline II helixtrans-69.2134.3175.649.30000109.8
4S80Confident85.4Confident67 Ų6748.1 Ų48.147%0.46927%0.265SS..PPolyproline II helixtrans-67132.4172.1-166.30000109.6N337S4-N337 WeakPolarHBondContact CA-O 3.44Å
5E88.2Confident86Confident43 Ų4349.3 Ų49.320%0.20128%0.276CS..EExtended strand (participates in β ladder)trans-120.7138.3171.6-173.1173.9177.300108.2R8 N337 P339E5-R8 IonicContact OE1-CZ 2.73Å; E5-R8 IonicContact OE1-NE 3.87Å; E5-R8 PolarHBondContact OE1-NE 3.32Å; E5-R8 VanDerWaalsContact OE1-NE 3.15Å; E5-R8 IonicContact OE1-NH2 3.58Å; E5-R8 PolarHBondContact OE1-NH2 2.88Å; E5-N337 PolarHBondContact N-O 3.02Å; E5-N337 PolarHBondContact O-N 3.45Å; E5-P339 HydrophobicContact CB-CG 4.19Å
6C90Very high86.5Confident61 Ų6147.6 Ų47.641%0.41227%0.266SS..EExtended strand (participates in β ladder)trans-78.2153.7173.5-67.10000110.9R8 K333 I335C6-R8 PolarHBondContact O-N 3.23Å; C6-K333 WeakPolarHBondContact CB-O 3.02Å; C6-I335 CarbonylContact C-O 3.52Å; C6-I335 VanDerWaalsContact CA-O 3.23Å; C6-I335 WeakPolarHBondContact CA-O 3.28Å
7V93.7Very high86.8Confident1 Ų148 Ų481%0.00627%0.267CS..PPolyproline II helixtrans-60128169174.50000108.7V9 T306 M308 I335V7-V9 HydrophobicContact CG1-CG2 4.36Å; V7-T306 HydrophobicContact CG1-CG2 4.06Å; V7-T306 HydrophobicContact CG2-CG2 4.42Å; V7-M308 HydrophobicContact CG1-CB 4.35Å; V7-I335 HydrophobicContact CB-CB 4.38Å; V7-I335 HydrophobicContact CG2-CB 3.71Å; V7-I335 HydrophobicContact CG2-CD1 4.44Å; V7-I335 HydrophobicContact CG2-CG2 3.79Å; V7-I335 PolarHBondContact N-O 2.94Å
8R94.1Very high87Confident41 Ų4154.4 Ų54.416%0.15530%0.295CS..EExtended strand (participates in β ladder)trans-81.5126.6176.1-64.9-172-140.7158.410.2109.7E5 C6 D56 T306 I307 M308E5-R8 IonicContact OE1-CZ 2.73Å; E5-R8 IonicContact OE1-NE 3.87Å; E5-R8 PolarHBondContact OE1-NE 3.32Å; E5-R8 VanDerWaalsContact OE1-NE 3.15Å; E5-R8 IonicContact OE1-NH2 3.58Å; E5-R8 PolarHBondContact OE1-NH2 2.88Å; C6-R8 PolarHBondContact O-N 3.23Å; R8-D56 VanDerWaalsContact CA-OD2 3.28Å; R8-D56 WeakPolarHBondContact CA-OD2 3.3Å; R8-T306 PolarHBondContact N-O 2.87Å; R8-I307 HydrophobicContact CB-CG1 4.33Å; R8-I307 CarbonylContact O-C 3.42Å; R8-I307 WeakPolarHBondContact O-CA 3.33Å; R8-M308 PolarHBondContact O-N 3.39Å
9V96.1Very high87.1Confident0 Ų058.5 Ų58.50%031%0.312CS..EExtended strand (participates in β ladder)trans-115.2123.4-177.4-179.10000109.3V7 F55 D56 M308 A329 A332 K333V7-V9 HydrophobicContact CG1-CG2 4.36Å; V9-F55 HydrophobicContact CB-CD1 4.19Å; V9-F55 HydrophobicContact CG1-CD1 3.52Å; V9-F55 HydrophobicContact CG1-CE1 3.93Å; V9-F55 HydrophobicContact CG1-CG 4.48Å; V9-D56 PolarHBondContact N-OD2 3.43Å; V9-D56 WeakPolarHBondContact O-CB 3.32Å; V9-D56 PolarHBondContact O-N 3.22Å; V9-M308 HydrophobicContact CG2-CB 4.3Å; V9-A329 HydrophobicContact CG1-CB 3.65Å; V9-A332 HydrophobicContact CG2-CB 4.17Å; V9-K333 HydrophobicContact CB-CB 4.32Å; V9-K333 HydrophobicContact CG2-CB 3.81Å; V9-K333 HydrophobicContact CG2-CG 4.39Å
10V96.4Very high87.4Confident1 Ų155.8 Ų55.81%0.00630%0.297CS..EExtended strand (participates in β ladder)trans-118.6136.2-179.11750000108.7A57 F59 V72 I307 M308 I309 A310V10-A57 WeakPolarHBondContact CA-O 3.44Å; V10-A57 HydrophobicContact CG1-CB 4.35Å; V10-A57 HydrophobicContact CG2-CB 4.25Å; V10-F59 HydrophobicContact CG1-CD2 3.41Å; V10-F59 VanDerWaalsContact CG1-CD2 3.41Å; V10-F59 HydrophobicContact CG1-CE2 3.33Å; V10-V72 HydrophobicContact CG2-CB 4.21Å; V10-V72 HydrophobicContact CG2-CG1 3.63Å; V10-V72 HydrophobicContact CG2-CG2 3.82Å; V10-I307 HydrophobicContact CG2-CG2 4.35Å; V10-M308 PolarHBondContact N-O 3.38Å; V10-I309 CarbonylContact O-C 3.55Å; V10-I309 WeakPolarHBondContact O-CA 3.45Å; V10-A310 PolarHBondContact O-N 3.39Å
11V97.4Very high87.7Confident0 Ų058.6 Ų58.60%031%0.31CS..EExtended strand (participates in β ladder)trans-104.6137172.1169.60000110.2C38 F55 A57 V58 F59 A310 L312 L326V11-C38 HydrophobicContact CG1-CB 4.46Å; V11-F55 HydrophobicContact CB-CD2 4.12Å; V11-F55 HydrophobicContact CB-CE2 4.48Å; V11-F55 HydrophobicContact CG2-CB 4.39Å; V11-F55 HydrophobicContact CG2-CD1 4.09Å; V11-F55 HydrophobicContact CG2-CD2 3.28Å; V11-F55 HydrophobicContact CG2-CE1 4.17Å; V11-F55 HydrophobicContact CG2-CE2 3.37Å; V11-F55 HydrophobicContact CG2-CG 3.65Å; V11-F55 HydrophobicContact CG2-CZ 3.83Å; V11-A57 PolarHBondContact N-O 3.35Å; V11-V58 HydrophobicContact CB-CG2 4.39Å; V11-V58 CarbonylContact O-C 3.59Å; V11-V58 WeakPolarHBondContact O-CA 3.31Å; V11-F59 PolarHBondContact O-N 2.94Å; V11-A310 WeakPolarHBondContact CA-O 3.4Å; V11-A310 HydrophobicContact CG2-CB 4.1Å; V11-L312 HydrophobicContact CG1-CD1 3.37Å; V11-L312 HydrophobicContact CG1-CG 4.08Å; V11-L326 HydrophobicContact CG2-CD2 4.14Å
12R97Very high90.1Very high16 Ų1652.6 Ų52.66%0.0629%0.29CS..EExtended strand (participates in β ladder)trans-127.4121.1170.6-172.5-176.3-172169.69109.7F59 A63 T65 L68 T101 A310 C311 L312R12-F59 WeakPolarHBondContact CA-O 3.5Å; R12-F59 HydrophobicContact CB-CB 4.35Å; R12-F59 HydrophobicContact CG-CB 4.15Å; R12-A63 PolarHBondContact NH2-O 3.07Å; R12-T65 PolarHBondContact NH1-OG1 2.84Å; R12-T65 PolarHBondContact NH2-OG1 2.73Å; R12-L68 HydrophobicContact CB-CD1 4.35Å; R12-L68 HydrophobicContact CG-CD1 4.38Å; R12-T101 WeakPolarHBondContact CD-OG1 3.23Å; R12-T101 PolarHBondContact NH1-OG1 3.03Å; R12-A310 PolarHBondContact N-O 3.25Å; R12-C311 WeakPolarHBondContact O-CA 3.39Å; R12-L312 PolarHBondContact O-N 3.02Å
13S96.4Very high91.8Very high6 Ų654 Ų544%0.04229%0.292CS..EExtended strand (participates in β ladder)trans-97.3133.9170.2-170.40000109.6F59 D60S13-F59 PolarHBondContact N-O 2.78Å; S13-D60 CarbonylContact O-C 3.5Å; S13-D60 VanDerWaalsContact O-O 3.1Å
14R95Very high92.7Very high34 Ų3451.3 Ų51.313%0.12829%0.287CS..PPolyproline II helixtrans-94163.5173.165.1152175.679-1.8111.2E20 G95 L312 S313 P314R14-E20 IonicContact CZ-OE1 3.45Å; R14-E20 IonicContact CZ-OE2 2.7Å; R14-E20 IonicContact NH1-OE1 3.15Å; R14-E20 IonicContact NH1-OE2 3.77Å; R14-E20 PolarHBondContact NH1-OE2 2.85Å; R14-E20 VanDerWaalsContact NH2-CD 3.31Å; R14-E20 IonicContact NH2-OE1 2.83Å; R14-E20 PolarHBondContact NH2-OE1 3.31Å; R14-E20 IonicContact NH2-OE2 3.58Å; R14-E20 PolarHBondContact NH2-OE2 3.49Å; R14-G95 PolarHBondContact NE-O 3.25Å; R14-G95 PolarHBondContact NH2-O 3.21Å; R14-L312 PolarHBondContact N-O 2.85Å; R14-S313 PolarHBondContact NH2-OG 2.9Å; R14-P314 WeakPolarHBondContact O-CD 3.41Å; R14-P314 WeakPolarHBondContact O-CG 3.46Å
15P94.4Very high93.4Very high66 Ų6649 Ų4943%0.42927%0.27SS..PPolyproline II helixtrans-66.6164.7165.928-35.3000111.8K61P15-K61 HydrophobicContact CB-CB 4.18Å
16L94Very high93.6Very high21 Ų2149.8 Ų49.811%0.1128%0.278CS..PPolyproline II helixtrans-58.3137.4169.6-68.9173.3000110.4E20 M21 C25 Y27 P314 A315L16-E20 WeakPolarHBondContact CA-OE2 3.31Å; L16-E20 HydrophobicContact CB-CB 4.43Å; L16-E20 HydrophobicContact CD2-CB 3.98Å; L16-M21 HydrophobicContact CB-CG 3.88Å; L16-M21 HydrophobicContact CD1-CG 4.49Å; L16-C25 HydrophobicContact CD2-CB 4.34Å; L16-Y27 HydrophobicContact CD1-CD2 3.8Å; L16-Y27 HydrophobicContact CD1-CE2 3.29Å; L16-Y27 HydrophobicContact CG-CD2 4.32Å; L16-Y27 HydrophobicContact CG-CE1 4.12Å; L16-Y27 HydrophobicContact CG-CE2 3.72Å; L16-Y27 PolarHBondContact N-OH 3.5Å; L16-P314 HydrophobicContact CD2-CG 3.9Å; L16-P314 HydrophobicContact CG-CG 4.23Å; L16-A315 HydrophobicContact CD2-CB 3.66Å
17N91.3Very high93.8Very high55 Ų5552 Ų5229%0.29428%0.279SS..PPolyproline II helixtrans-85.3169.7175.270.817.8000111.1Q19 E20 M21N17-Q19 PolarHBondContact O-N 3.37Å; N17-Q19 PolarHBondContact OD1-N 2.86Å; N17-E20 PolarHBondContact N-OE2 3.28Å; N17-E20 PolarHBondContact O-N 2.95Å; N17-E20 VanDerWaalsContact OD1-CB 3.3Å; N17-E20 WeakPolarHBondContact OD1-CB 3.48Å; N17-E20 WeakPolarHBondContact OD1-CG 3.33Å; N17-E20 PolarHBondContact OD1-N 3.38Å; N17-E20 PolarHBondContact OD1-OE2 2.91Å; N17-M21 WeakPolarHBondContact O-CG 3.36Å; N17-M21 PolarHBondContact O-N 3.39Å
18E90.4Very high93.9Very high164 Ų16452.5 Ų52.577%0.76628%0.282SS*.Hα-helixtrans-56.7-38.3-178.4-65.4177.4-178.500112.9M21 S22E18-M21 HydrophobicContact CG-CE 4.26Å; E18-M21 PolarHBondContact O-N 3.23Å; E18-S22 WeakPolarHBondContact O-CB 3.49Å; E18-S22 PolarHBondContact O-N 2.91Å
19Q88.8Confident93.9Very high131 Ų13151.4 Ų51.461%0.61228%0.279SS*.Hα-helixtrans-66.8-46.2178.6-170.2-179.43.600111.9N17 M21 S22 M23N17-Q19 PolarHBondContact O-N 3.37Å; N17-Q19 PolarHBondContact OD1-N 2.86Å; Q19-M21 VanDerWaalsContact C-N 3.34Å; Q19-S22 PolarHBondContact O-N 2.82Å; Q19-S22 PolarHBondContact O-OG 3.49Å; Q19-M23 HydrophobicContact CG-CE 4.17Å; Q19-M23 WeakPolarHBondContact O-CG 3.44Å; Q19-M23 PolarHBondContact O-N 3.24Å
20E93Very high93.8Very high4 Ų456.5 Ų56.52%0.01931%0.306CS..Hα-helixtrans-65.1-38.8177.1-70.6163.216700111.5R14 L16 N17 M23 G24 C25 S313 A315 N318R14-E20 IonicContact CZ-OE1 3.45Å; R14-E20 IonicContact CZ-OE2 2.7Å; R14-E20 IonicContact NH1-OE1 3.15Å; R14-E20 IonicContact NH1-OE2 3.77Å; R14-E20 PolarHBondContact NH1-OE2 2.85Å; R14-E20 VanDerWaalsContact NH2-CD 3.31Å; R14-E20 IonicContact NH2-OE1 2.83Å; R14-E20 PolarHBondContact NH2-OE1 3.31Å; R14-E20 IonicContact NH2-OE2 3.58Å; R14-E20 PolarHBondContact NH2-OE2 3.49Å; L16-E20 WeakPolarHBondContact CA-OE2 3.31Å; L16-E20 HydrophobicContact CB-CB 4.43Å; L16-E20 HydrophobicContact CD2-CB 3.98Å; N17-E20 PolarHBondContact N-OE2 3.28Å; N17-E20 PolarHBondContact O-N 2.95Å; N17-E20 VanDerWaalsContact OD1-CB 3.3Å; N17-E20 WeakPolarHBondContact OD1-CB 3.48Å; N17-E20 WeakPolarHBondContact OD1-CG 3.33Å; N17-E20 PolarHBondContact OD1-N 3.38Å; N17-E20 PolarHBondContact OD1-OE2 2.91Å; E20-M23 HydrophobicContact CB-CE 4.49Å; E20-M23 HydrophobicContact CG-CE 4.15Å; E20-M23 PolarHBondContact O-N 3.28Å; E20-G24 PolarHBondContact O-N 2.81Å; E20-C25 HydrophobicContact CB-CB 4.08Å; E20-C25 WeakPolarHBondContact O-CB 3.42Å; E20-C25 PolarHBondContact O-N 3.29Å; E20-S313 PolarHBondContact OE1-OG 3.25Å; E20-A315 HydrophobicContact CB-CB 4.34Å; E20-A315 HydrophobicContact CG-CB 3.86Å; E20-N318 PolarHBondContact OE1-ND2 2.81Å
21M93.5Very high93.7Very high115 Ų11557.5 Ų57.557%0.56731%0.313SS*.Hα-helixtrans-62.8-42.3172.2-70.2-171.3-68.700111.4L16 N17 E18 Q19 M23 G24L16-M21 HydrophobicContact CB-CG 3.88Å; L16-M21 HydrophobicContact CD1-CG 4.49Å; N17-M21 WeakPolarHBondContact O-CG 3.36Å; N17-M21 PolarHBondContact O-N 3.39Å; E18-M21 HydrophobicContact CG-CE 4.26Å; E18-M21 PolarHBondContact O-N 3.23Å; Q19-M21 VanDerWaalsContact C-N 3.34Å; M21-M23 VanDerWaalsContact C-N 3.28Å; M21-M23 PolarHBondContact O-N 2.97Å; M21-G24 PolarHBondContact O-N 3.29Å; M21-G24 VanDerWaalsContact O-N 3.07Å
22S93.9Very high93.4Very high98 Ų9860.6 Ų60.669%0.68533%0.329SS*.Hα-helixtrans-66-28.617777.50000113.5E18 Q19 G24E18-S22 WeakPolarHBondContact O-CB 3.49Å; E18-S22 PolarHBondContact O-N 2.91Å; Q19-S22 PolarHBondContact O-N 2.82Å; Q19-S22 PolarHBondContact O-OG 3.49Å; S22-G24 VanDerWaalsContact C-N 3.27Å
23M91.8Very high93.1Very high95 Ų9562.5 Ų62.547%0.46834%0.343SS..THydrogen-bonded Turntrans-80.7-6.3174.5-68.9-175.3-60.400113.1Q19 E20 M21 C25Q19-M23 HydrophobicContact CG-CE 4.17Å; Q19-M23 WeakPolarHBondContact O-CG 3.44Å; Q19-M23 PolarHBondContact O-N 3.24Å; E20-M23 HydrophobicContact CB-CE 4.49Å; E20-M23 HydrophobicContact CG-CE 4.15Å; E20-M23 PolarHBondContact O-N 3.28Å; M21-M23 VanDerWaalsContact C-N 3.28Å; M21-M23 PolarHBondContact O-N 2.97Å; M23-C25 VanDerWaalsContact C-N 3.33Å
24G92.5Very high92.6Very high58 Ų5866.2 Ų66.260%0.59837%0.369SS*.THydrogen-bonded Turntrans7028.1-176.300000113.6E20 M21 S22E20-G24 PolarHBondContact O-N 2.81Å; M21-G24 PolarHBondContact O-N 3.29Å; M21-G24 VanDerWaalsContact O-N 3.07Å; S22-G24 VanDerWaalsContact C-N 3.27Å
25C93.4Very high92.2Very high18 Ų1866.3 Ų66.312%0.12238%0.375CS..PPolyproline II helixtrans-61.3143.7179.7-74.90000112.3L16 E20 M23 A315 D316L16-C25 HydrophobicContact CD2-CB 4.34Å; E20-C25 HydrophobicContact CB-CB 4.08Å; E20-C25 WeakPolarHBondContact O-CB 3.42Å; E20-C25 PolarHBondContact O-N 3.29Å; M23-C25 VanDerWaalsContact C-N 3.33Å; C25-A315 HydrophobicContact CB-CB 3.98Å; C25-D316 WeakPolarHBondContact CA-OD1 3.26Å; C25-D316 VanDerWaalsContact CB-OD1 3.27Å; C25-D316 WeakPolarHBondContact CB-OD1 3.3Å; C25-D316 PolarHBondContact SG-OD1 2.81Å
26T93.4Very high92.1Very high60 Ų6063.7 Ų63.737%0.36836%0.358SS..PPolyproline II helixtrans-98.5154.8174.960.90000112.1D316T26-D316 VanDerWaalsContact N-CG 3.34Å; T26-D316 PolarHBondContact N-OD1 3.05Å; T26-D316 PolarHBondContact N-OD2 3.31Å; T26-D316 PolarHBondContact O-N 3.18Å; T26-D316 PolarHBondContact OG1-OD2 3.45Å
27Y94.4Very high92Very high109 Ų10965.8 Ų65.843%0.42737%0.367SS..BIsolated β-bridgetrans-74.5122.5173.7-76.9-98.2000110.1L16 K61 P314L16-Y27 HydrophobicContact CD1-CD2 3.8Å; L16-Y27 HydrophobicContact CD1-CE2 3.29Å; L16-Y27 HydrophobicContact CG-CD2 4.32Å; L16-Y27 HydrophobicContact CG-CE1 4.12Å; L16-Y27 HydrophobicContact CG-CE2 3.72Å; L16-Y27 PolarHBondContact N-OH 3.5Å; Y27-K61 HydrophobicContact CE1-CD 4Å; Y27-P314 CarbonylContact C-O 3.58Å; Y27-P314 WeakPolarHBondContact CA-O 3.33Å; Y27-P314 HydrophobicContact CD1-CB 3.57Å; Y27-P314 HydrophobicContact CD1-CG 4.1Å; Y27-P314 HydrophobicContact CE1-CB 3.85Å; Y27-P314 HydrophobicContact CE1-CG 3.88Å
28V94.6Very high92.2Very high11 Ų1163.2 Ų63.27%0.06735%0.353CS..  trans-107.9-10.1173.3-65.10000113.6I40 A41 P43 P314 D316 Y319V28-I40 WeakPolarHBondContact O-CA 3.44Å; V28-A41 PolarHBondContact O-N 2.85Å; V28-P43 HydrophobicContact CG1-CB 4.05Å; V28-P43 HydrophobicContact CG1-CG 4.15Å; V28-P314 WeakPolarHBondContact CG2-O 3.46Å; V28-P314 PolarHBondContact N-O 2.99Å; V28-D316 HydrophobicContact CG1-CB 3.66Å; V28-Y319 HydrophobicContact CB-CD2 4.42Å; V28-Y319 HydrophobicContact CG2-CD2 4.27Å
29L94.7Very high92.4Very high17 Ų1756.9 Ų56.99%0.08933%0.326CS..EExtended strand (participates in β ladder)trans-104.7132.8177.3-70176.9000110.9T39 I40 L312 S313 P314 L326L29-T39 WeakPolarHBondContact CA-O 3.41Å; L29-I40 HydrophobicContact CD2-CB 3.63Å; L29-I40 HydrophobicContact CD2-CD1 3.79Å; L29-I40 HydrophobicContact CD2-CG1 3.53Å; L29-I40 HydrophobicContact CG-CG1 4.44Å; L29-L312 HydrophobicContact CD1-CB 3.6Å; L29-L312 HydrophobicContact CD1-CD1 3.95Å; L29-L312 HydrophobicContact CD1-CG 4.41Å; L29-L312 HydrophobicContact CD2-CD1 4.47Å; L29-S313 VanDerWaalsContact CD1-O 3.23Å; L29-S313 WeakPolarHBondContact CD1-O 3.33Å; L29-P314 HydrophobicContact CB-CB 4.32Å; L29-L326 HydrophobicContact CD2-CD1 4.23Å
30D93.8Very high92.6Very high107 Ų10750.7 Ų50.757%0.57230%0.297SS*.EExtended strand (participates in β ladder)trans-122.1132.3167-175.540.3000108.6T39D30-T39 PolarHBondContact N-O 3.43Å; D30-T39 PolarHBondContact O-N 3.41Å
31T93.7Very high92.6Very high23 Ų2352.4 Ų52.414%0.14131%0.312CS..EExtended strand (participates in β ladder)trans-125.5126.5-174.146.70000108.8P33 C38 V58 D60T31-P33 WeakPolarHBondContact O-CD 3.39Å; T31-C38 HydrophobicContact CG2-CB 4.4Å; T31-V58 HydrophobicContact CG2-CG1 3.66Å; T31-D60 WeakPolarHBondContact OG1-CA 3.32Å; T31-D60 VanDerWaalsContact OG1-CB 3.24Å; T31-D60 WeakPolarHBondContact OG1-CB 3.21Å
32D92.2Very high92.5Very high64 Ų6448.7 Ų48.734%0.34230%0.295SS..EExtended strand (participates in β ladder)trans-114.998.6174.7-177.1-2.7000109.7S34 C35 C36 Q37D32-S34 VanDerWaalsContact CG-OG 3.32Å; D32-S34 PolarHBondContact O-N 3.39Å; D32-S34 WeakPolarHBondContact OD1-CA 3.32Å; D32-S34 VanDerWaalsContact OD1-CB 3.28Å; D32-S34 WeakPolarHBondContact OD1-CB 3.36Å; D32-S34 PolarHBondContact OD1-N 3.32Å; D32-S34 PolarHBondContact OD1-OG 3Å; D32-S34 PolarHBondContact OD2-OG 3.4Å; D32-C35 VanDerWaalsContact CB-SG 3.53Å; D32-C35 PolarHBondContact O-N 3.44Å; D32-C35 PolarHBondContact OD2-SG 2.83Å; D32-C36 PolarHBondContact O-N 3.19Å; D32-Q37 PolarHBondContact N-O 2.89Å; D32-Q37 PolarHBondContact O-N 2.89Å; D32-Q37 VanDerWaalsContact O-N 3.08Å
33P89.6Confident92.3Very high56 Ų5646.2 Ų46.236%0.36428%0.276SS..THydrogen-bonded Turntrans-60.3-25.9175.6-24.434.8000113.6T31 C36 V58 D60T31-P33 WeakPolarHBondContact O-CD 3.39Å; P33-C36 PolarHBondContact O-N 3.46Å; P33-V58 WeakPolarHBondContact CB-O 3.46Å; P33-D60 HydrophobicContact CG-CB 4.41Å
34S87.1Confident92.1Very high84 Ų8446.3 Ų46.359%0.58729%0.292SS*.THydrogen-bonded Turntrans-72.4-33.1-175.376.80000112.9D32 M500D32-S34 VanDerWaalsContact CG-OG 3.32Å; D32-S34 PolarHBondContact O-N 3.39Å; D32-S34 WeakPolarHBondContact OD1-CA 3.32Å; D32-S34 VanDerWaalsContact OD1-CB 3.28Å; D32-S34 WeakPolarHBondContact OD1-CB 3.36Å; D32-S34 PolarHBondContact OD1-N 3.32Å; D32-S34 PolarHBondContact OD1-OG 3Å; D32-S34 PolarHBondContact OD2-OG 3.4Å; S34-M500 WeakPolarHBondContact O-CE 3.48Å
35C86.1Confident91.7Very high37 Ų3746.7 Ų46.725%0.2528%0.28CS..THydrogen-bonded Turntrans-106.64.4174.467.70000113.6D32 Q37D32-C35 VanDerWaalsContact CB-SG 3.53Å; D32-C35 PolarHBondContact O-N 3.44Å; D32-C35 PolarHBondContact OD2-SG 2.83Å; C35-Q37 HydrophobicContact CB-CG 4.25Å; C35-Q37 PolarHBondContact O-N 3.37Å; C35-Q37 WeakPolarHBondContact SG-CB 3.43Å; C35-Q37 WeakPolarHBondContact SG-CG 3.46Å
36C91.8Very high91.1Very high10 Ų1055.6 Ų55.67%0.06831%0.311CS..THydrogen-bonded Turntrans55.136.2-175.4-62.30000113.1D32 P33 T54 F55 V58 M500D32-C36 PolarHBondContact O-N 3.19Å; P33-C36 PolarHBondContact O-N 3.46Å; C36-T54 WeakPolarHBondContact O-CA 3.47Å; C36-F55 WeakPolarHBondContact CB-O 3.41Å; C36-F55 PolarHBondContact O-N 2.96Å; C36-V58 WeakPolarHBondContact O-CG2 3.49Å; C36-M500 VanDerWaalsContact SG-SD 3.65Å
37Q93Very high90.6Very high66 Ų6659 Ų5931%0.30833%0.332SS..EExtended strand (participates in β ladder)trans-107.9146.3-179.8-64.8-178-8.300112.4D32 C35 V52 F53 T54D32-Q37 PolarHBondContact N-O 2.89Å; D32-Q37 PolarHBondContact O-N 2.89Å; D32-Q37 VanDerWaalsContact O-N 3.08Å; C35-Q37 HydrophobicContact CB-CG 4.25Å; C35-Q37 PolarHBondContact O-N 3.37Å; C35-Q37 WeakPolarHBondContact SG-CB 3.43Å; C35-Q37 WeakPolarHBondContact SG-CG 3.46Å; Q37-V52 HydrophobicContact CB-CG1 4.02Å; Q37-V52 HydrophobicContact CG-CG1 4.07Å; Q37-F53 CarbonylContact C-O 3.52Å; Q37-F53 VanDerWaalsContact CA-O 3.27Å; Q37-F53 WeakPolarHBondContact CA-O 3.28Å; Q37-T54 HydrophobicContact CG-CG2 4.3Å
38C94.6Very high90Very high0 Ų054.7 Ų54.70%032%0.319CS..EExtended strand (participates in β ladder)trans-125.1119.6170-178.90000108.3V11 T31 F53 F55 V58 L326V11-C38 HydrophobicContact CG1-CB 4.46Å; T31-C38 HydrophobicContact CG2-CB 4.4Å; C38-F53 PolarHBondContact N-O 2.91Å; C38-F53 PolarHBondContact O-N 2.84Å; C38-F55 HydrophobicContact CB-CE2 4.33Å; C38-V58 HydrophobicContact CB-CG1 4.5Å; C38-L326 HydrophobicContact CB-CD2 4.26Å
39T94.1Very high89.5Confident31 Ų3160.4 Ų60.419%0.1935%0.345CS..EExtended strand (participates in β ladder)trans-103.8131.2179.9-58.80000109.3L29 D30 P50 K51 V52L29-T39 WeakPolarHBondContact CA-O 3.41Å; D30-T39 PolarHBondContact N-O 3.43Å; D30-T39 PolarHBondContact O-N 3.41Å; T39-P50 HydrophobicContact CG2-CB 3.41Å; T39-P50 VanDerWaalsContact CG2-CB 3.41Å; T39-P50 HydrophobicContact CG2-CG 4.42Å; T39-K51 CarbonylContact C-O 3.56Å; T39-K51 VanDerWaalsContact CA-O 3.24Å; T39-K51 WeakPolarHBondContact CA-O 3.36Å; T39-V52 HydrophobicContact CG2-CG2 4.22Å
40I94.4Very high89.2Confident1 Ų162.9 Ų62.91%0.00536%0.362CS..EExtended strand (participates in β ladder)trans-124.8121.3177.3-166.3178.6000110.5V28 L29 K51 F53 Y319 L323 L326V28-I40 WeakPolarHBondContact O-CA 3.44Å; L29-I40 HydrophobicContact CD2-CB 3.63Å; L29-I40 HydrophobicContact CD2-CD1 3.79Å; L29-I40 HydrophobicContact CD2-CG1 3.53Å; L29-I40 HydrophobicContact CG-CG1 4.44Å; I40-K51 HydrophobicContact CG2-CB 3.85Å; I40-K51 PolarHBondContact N-O 3.39Å; I40-K51 PolarHBondContact O-N 2.88Å; I40-F53 HydrophobicContact CG2-CD2 4.37Å; I40-F53 HydrophobicContact CG2-CE2 3.85Å; I40-Y319 HydrophobicContact CD1-CD2 3.65Å; I40-Y319 HydrophobicContact CD1-CE2 3.75Å; I40-Y319 HydrophobicContact CG1-CD2 3.75Å; I40-Y319 HydrophobicContact CG1-CE2 3.67Å; I40-L323 HydrophobicContact CD1-CB 4.02Å; I40-L323 HydrophobicContact CG2-CD1 4.04Å; I40-L326 HydrophobicContact CB-CD1 4.13Å; I40-L326 HydrophobicContact CD1-CD1 4.12Å; I40-L326 HydrophobicContact CG2-CD1 3.98Å
41A92.7Very high89.1Confident41 Ų4158.7 Ų58.734%0.33934%0.339SS..  trans-97.1135.8179.700000110.8V28 P43 P50 Y319V28-A41 PolarHBondContact O-N 2.85Å; A41-P43 VanDerWaalsContact O-CD 3.3Å; A41-P43 WeakPolarHBondContact O-CD 3.28Å; A41-P50 HydrophobicContact CB-CB 4.42Å; A41-P50 HydrophobicContact CB-CG 4.42Å; A41-Y319 WeakPolarHBondContact O-CD2 3.39Å; A41-Y319 VanDerWaalsContact O-CE2 3.22Å; A41-Y319 WeakPolarHBondContact O-CE2 3.46Å
42N90.5Very high89Confident37 Ų3761.3 Ų61.320%0.19835%0.354CS..  trans-75.3117.1178.5-171.6-16.7000110.2A44 D45 Y319N42-A44 VanDerWaalsContact C-N 3.27Å; N42-A44 PolarHBondContact O-N 2.99Å; N42-A44 WeakPolarHBondContact OD1-CB 3.35Å; N42-A44 PolarHBondContact OD1-N 3.2Å; N42-D45 CarbonylContact O-C 3.36Å; N42-D45 PolarHBondContact O-N 3.17Å; N42-Y319 HydrophobicContact CB-CE1 4.41Å; N42-Y319 HydrophobicContact CB-CE2 4.17Å; N42-Y319 WeakPolarHBondContact CB-OH 3.43Å
43P89.5Confident89.1Confident46 Ų4659.2 Ų59.230%0.29934%0.342SS..SBendtrans-68-26.7179.227.6-34.2000113V28 A41 D316 Y319V28-P43 HydrophobicContact CG1-CB 4.05Å; V28-P43 HydrophobicContact CG1-CG 4.15Å; A41-P43 VanDerWaalsContact O-CD 3.3Å; A41-P43 WeakPolarHBondContact O-CD 3.28Å; P43-D316 HydrophobicContact CB-CB 3.95Å; P43-D316 HydrophobicContact CG-CB 4.19Å; P43-Y319 VanDerWaalsContact CD-CD2 3.42Å; P43-Y319 VanDerWaalsContact CD-CG 3.41Å; P43-Y319 HydrophobicContact CG-CD1 4.42Å; P43-Y319 HydrophobicContact CG-CD2 4.39Å; P43-Y319 HydrophobicContact CG-CG 3.99Å
44A87.2Confident89.2Confident96 Ų9657.8 Ų57.879%0.79333%0.333SS*.SBendtrans-81.2-26.5-179.500000113.2N42N42-A44 VanDerWaalsContact C-N 3.27Å; N42-A44 PolarHBondContact O-N 2.99Å; N42-A44 WeakPolarHBondContact OD1-CB 3.35Å; N42-A44 PolarHBondContact OD1-N 3.2Å
45D85.8Confident89.6Confident66 Ų6654 Ų5435%0.35331%0.306SS..  trans-131.789.3176.6-177.86.5000110.1N42 T47 A48N42-D45 CarbonylContact O-C 3.36Å; N42-D45 PolarHBondContact O-N 3.17Å; D45-T47 PolarHBondContact O-N 3.38Å; D45-T47 PolarHBondContact OD1-N 2.85Å; D45-T47 PolarHBondContact OD1-OG1 2.88Å; D45-A48 HydrophobicContact CB-CB 4.11Å; D45-A48 WeakPolarHBondContact O-CB 3.49Å; D45-A48 PolarHBondContact O-N 3.33Å; D45-A48 PolarHBondContact OD1-N 3.4Å; D45-A48 VanDerWaalsContact OD2-CB 3.26Å; D45-A48 WeakPolarHBondContact OD2-CB 3.41Å
46R80.1Confident89.9Confident205 Ų20554.1 Ų54.177%0.77430%0.304SS*.THydrogen-bonded Turntrans-73.9-12.4178.3-63.9-174.5178.2-155.6-2.3113.5A48R46-A48 VanDerWaalsContact C-N 3.32Å
47T82.7Confident90Very high133 Ų13353.9 Ų53.982%0.81630%0.302SS*.THydrogen-bonded Turntrans-82-20.3176.969.60000111.8D45D45-T47 PolarHBondContact O-N 3.38Å; D45-T47 PolarHBondContact OD1-N 2.85Å; D45-T47 PolarHBondContact OD1-OG1 2.88Å
48A81.5Confident90.1Very high17 Ų1751 Ų5114%0.1429%0.289CS..SBendtrans-69.8135.2177.200000111.5D45 R46D45-A48 HydrophobicContact CB-CB 4.11Å; D45-A48 WeakPolarHBondContact O-CB 3.49Å; D45-A48 PolarHBondContact O-N 3.33Å; D45-A48 PolarHBondContact OD1-N 3.4Å; D45-A48 VanDerWaalsContact OD2-CB 3.26Å; D45-A48 WeakPolarHBondContact OD2-CB 3.41Å; R46-A48 VanDerWaalsContact C-N 3.32Å
49E84.3Confident90.2Very high131 Ų13151.4 Ų51.461%0.61229%0.291SS*.PPolyproline II helixtrans-57134.1170.4-69.1179.2177.400110.9K541E49-K541 PolarHBondContact O-NZ 3.42Å
50P89.1Confident90.2Very high70 Ų7051.9 Ų51.946%0.45529%0.292SS..PPolyproline II helixtrans-59.6147175.1-23.934.2000111.9T39 A41T39-P50 HydrophobicContact CG2-CB 3.41Å; T39-P50 VanDerWaalsContact CG2-CB 3.41Å; T39-P50 HydrophobicContact CG2-CG 4.42Å; A41-P50 HydrophobicContact CB-CB 4.42Å; A41-P50 HydrophobicContact CB-CG 4.42Å
51K90.7Very high90Very high19 Ų1956.2 Ų56.28%0.08331%0.311CS..EExtended strand (participates in β ladder)trans-86.9133.7176.5-67.9177.2179.2168.10109.7T39 I40 F53 L323 D542 D545T39-K51 CarbonylContact C-O 3.56Å; T39-K51 VanDerWaalsContact CA-O 3.24Å; T39-K51 WeakPolarHBondContact CA-O 3.36Å; I40-K51 HydrophobicContact CG2-CB 3.85Å; I40-K51 PolarHBondContact N-O 3.39Å; I40-K51 PolarHBondContact O-N 2.88Å; K51-F53 HydrophobicContact CB-CE2 3.89Å; K51-F53 HydrophobicContact CB-CZ 4.5Å; K51-L323 HydrophobicContact CD-CD1 3.78Å; K51-D542 WeakPolarHBondContact CE-OD1 3.21Å; K51-D542 IonicContact NZ-OD1 3.83Å; K51-D545 WeakPolarHBondContact CE-OD2 3.24Å; K51-D545 IonicContact NZ-OD2 3.06Å; K51-D545 PolarHBondContact NZ-OD2 2.92Å
52V91.7Very high90Very high77 Ų7760.1 Ų60.147%0.46732%0.323SS..EExtended strand (participates in β ladder)trans-113.3127.1179.9-174.80000109.1Q37 T39Q37-V52 HydrophobicContact CB-CG1 4.02Å; Q37-V52 HydrophobicContact CG-CG1 4.07Å; T39-V52 HydrophobicContact CG2-CG2 4.22Å
53F94Very high90.2Very high21 Ų2158.8 Ų58.89%0.09232%0.317CS..EExtended strand (participates in β ladder)trans-117145175-63.8-90.6000109.9Q37 C38 I40 K51 F55 L323 L326 R327 N330Q37-F53 CarbonylContact C-O 3.52Å; Q37-F53 VanDerWaalsContact CA-O 3.27Å; Q37-F53 WeakPolarHBondContact CA-O 3.28Å; C38-F53 PolarHBondContact N-O 2.91Å; C38-F53 PolarHBondContact O-N 2.84Å; I40-F53 HydrophobicContact CG2-CD2 4.37Å; I40-F53 HydrophobicContact CG2-CE2 3.85Å; K51-F53 HydrophobicContact CB-CE2 3.89Å; K51-F53 HydrophobicContact CB-CZ 4.5Å; F53-F55 HydrophobicContact CB-CD2 4.29Å; F53-F55 HydrophobicContact CB-CE2 3.35Å; F53-F55 HydrophobicContact CB-CZ 3.67Å; F53-F55 HydrophobicContact CD1-CZ 4.49Å; F53-F55 HydrophobicContact CG-CE2 4.35Å; F53-F55 HydrophobicContact CG-CZ 4.31Å; F53-L323 HydrophobicContact CE2-CD1 4.01Å; F53-L323 HydrophobicContact CZ-CD1 3.91Å; F53-L326 HydrophobicContact CB-CD2 4.37Å; F53-L326 HydrophobicContact CD1-CB 4.35Å; F53-L326 HydrophobicContact CD2-CB 4.01Å; F53-L326 HydrophobicContact CD2-CD1 3.87Å; F53-L326 HydrophobicContact CD2-CD2 4.3Å; F53-L326 HydrophobicContact CD2-CG 4.3Å; F53-L326 HydrophobicContact CE1-CB 4.3Å; F53-L326 HydrophobicContact CE2-CB 3.95Å; F53-L326 HydrophobicContact CE2-CD1 3.97Å; F53-L326 HydrophobicContact CG-CB 4.21Å; F53-L326 HydrophobicContact CG-CD2 4.37Å; F53-L326 HydrophobicContact CZ-CB 4.1Å; F53-R327 HydrophobicContact CE1-CG 4.18Å; F53-R327 HydrophobicContact CZ-CG 4.13Å; F53-N330 HydrophobicContact CD1-CB 4.28Å
54T92.3Very high90.5Very high26 Ų2658.4 Ų58.416%0.1631%0.314CS..EExtended strand (participates in β ladder)trans-123.3124.2-179.3-47.90000111.4C36 Q37 K333C36-T54 WeakPolarHBondContact O-CA 3.47Å; Q37-T54 HydrophobicContact CG-CG2 4.3Å; T54-K333 PolarHBondContact O-NZ 3.33Å
55F94.8Very high90.9Very high5 Ų553.9 Ų53.92%0.02228%0.276CS..  trans-118-177.7-174.1-63.1-74.5000111.8V9 V11 C36 C38 F53 V58 L326 A329 N330V9-F55 HydrophobicContact CB-CD1 4.19Å; V9-F55 HydrophobicContact CG1-CD1 3.52Å; V9-F55 HydrophobicContact CG1-CE1 3.93Å; V9-F55 HydrophobicContact CG1-CG 4.48Å; V11-F55 HydrophobicContact CB-CD2 4.12Å; V11-F55 HydrophobicContact CB-CE2 4.48Å; V11-F55 HydrophobicContact CG2-CB 4.39Å; V11-F55 HydrophobicContact CG2-CD1 4.09Å; V11-F55 HydrophobicContact CG2-CD2 3.28Å; V11-F55 HydrophobicContact CG2-CE1 4.17Å; V11-F55 HydrophobicContact CG2-CE2 3.37Å; V11-F55 HydrophobicContact CG2-CG 3.65Å; V11-F55 HydrophobicContact CG2-CZ 3.83Å; C36-F55 WeakPolarHBondContact CB-O 3.41Å; C36-F55 PolarHBondContact O-N 2.96Å; C38-F55 HydrophobicContact CB-CE2 4.33Å; F53-F55 HydrophobicContact CB-CD2 4.29Å; F53-F55 HydrophobicContact CB-CE2 3.35Å; F53-F55 HydrophobicContact CB-CZ 3.67Å; F53-F55 HydrophobicContact CD1-CZ 4.49Å; F53-F55 HydrophobicContact CG-CE2 4.35Å; F53-F55 HydrophobicContact CG-CZ 4.31Å; F55-V58 HydrophobicContact CB-CG2 4.28Å; F55-V58 HydrophobicContact CD2-CG2 4.3Å; F55-L326 HydrophobicContact CE2-CD2 3.48Å; F55-L326 VanDerWaalsContact CE2-CD2 3.48Å; F55-L326 HydrophobicContact CZ-CD2 3.64Å; F55-A329 HydrophobicContact CE1-CB 3.66Å; F55-A329 HydrophobicContact CZ-CB 4.16Å; F55-N330 HydrophobicContact CE1-CB 4.42Å
56D93.3Very high91.3Very high38 Ų3854.2 Ų54.220%0.20328%0.276CS..SBendtrans-78.7-26.3177.5-56.9-52.3000111.6R8 V9 K333 M497R8-D56 VanDerWaalsContact CA-OD2 3.28Å; R8-D56 WeakPolarHBondContact CA-OD2 3.3Å; V9-D56 PolarHBondContact N-OD2 3.43Å; V9-D56 WeakPolarHBondContact O-CB 3.32Å; V9-D56 PolarHBondContact O-N 3.22Å; D56-K333 WeakPolarHBondContact OD1-CE 3.4Å; D56-K333 IonicContact OD1-NZ 3.32Å; D56-M497 WeakPolarHBondContact O-CE 3.46Å
57A93.8Very high92Very high5 Ų548 Ų484%0.04126%0.257CS..EExtended strand (participates in β ladder)trans-156.4150.816700000109.9V10 V11 F59 V72 M497V10-A57 WeakPolarHBondContact CA-O 3.44Å; V10-A57 HydrophobicContact CG1-CB 4.35Å; V10-A57 HydrophobicContact CG2-CB 4.25Å; V11-A57 PolarHBondContact N-O 3.35Å; A57-F59 HydrophobicContact CB-CE2 3.86Å; A57-F59 HydrophobicContact CB-CZ 4.18Å; A57-V72 HydrophobicContact CB-CG2 4.15Å; A57-M497 HydrophobicContact CB-CE 4Å
58V95.4Very high92.7Very high5 Ų541.8 Ų41.83%0.0322%0.219CC..EExtended strand (participates in β ladder)trans-129.5129.9175.8-1800000109V11 T31 P33 C36 C38 F55V11-V58 HydrophobicContact CB-CG2 4.39Å; V11-V58 CarbonylContact O-C 3.59Å; V11-V58 WeakPolarHBondContact O-CA 3.31Å; T31-V58 HydrophobicContact CG2-CG1 3.66Å; P33-V58 WeakPolarHBondContact CB-O 3.46Å; C36-V58 WeakPolarHBondContact O-CG2 3.49Å; C38-V58 HydrophobicContact CB-CG1 4.5Å; F55-V58 HydrophobicContact CB-CG2 4.28Å; F55-V58 HydrophobicContact CD2-CG2 4.3Å
59F96.2Very high93.4Very high9 Ų941.3 Ų41.34%0.03921%0.214CC..EExtended strand (participates in β ladder)trans-115.5123.2178.3-64.5-76.2000109.3V10 V11 R12 S13 A57 A63 L67 L68 D71 V72V10-F59 HydrophobicContact CG1-CD2 3.41Å; V10-F59 VanDerWaalsContact CG1-CD2 3.41Å; V10-F59 HydrophobicContact CG1-CE2 3.33Å; V11-F59 PolarHBondContact O-N 2.94Å; R12-F59 WeakPolarHBondContact CA-O 3.5Å; R12-F59 HydrophobicContact CB-CB 4.35Å; R12-F59 HydrophobicContact CG-CB 4.15Å; S13-F59 PolarHBondContact N-O 2.78Å; A57-F59 HydrophobicContact CB-CE2 3.86Å; A57-F59 HydrophobicContact CB-CZ 4.18Å; F59-A63 HydrophobicContact CB-CB 3.69Å; F59-A63 HydrophobicContact CD1-CB 3.93Å; F59-A63 HydrophobicContact CG-CB 4.28Å; F59-L67 HydrophobicContact CD1-CD2 4.34Å; F59-L67 HydrophobicContact CD1-CG 4.5Å; F59-L67 HydrophobicContact CE1-CD2 4.29Å; F59-L67 HydrophobicContact CE1-CG 4.04Å; F59-L68 HydrophobicContact CD1-CB 4.27Å; F59-L68 HydrophobicContact CD2-CB 4.22Å; F59-L68 HydrophobicContact CD2-CD1 3.81Å; F59-L68 HydrophobicContact CD2-CG 3.92Å; F59-L68 HydrophobicContact CE1-CB 4.13Å; F59-L68 HydrophobicContact CE2-CB 4.07Å; F59-L68 HydrophobicContact CE2-CD1 4.16Å; F59-L68 HydrophobicContact CE2-CG 3.75Å; F59-L68 HydrophobicContact CG-CB 4.32Å; F59-L68 HydrophobicContact CG-CD1 4.29Å; F59-L68 HydrophobicContact CG-CG 4.47Å; F59-L68 HydrophobicContact CZ-CB 4.03Å; F59-L68 HydrophobicContact CZ-CG 4.18Å; F59-D71 HydrophobicContact CE1-CB 4.49Å; F59-D71 HydrophobicContact CZ-CB 4.02Å; F59-V72 HydrophobicContact CE2-CG2 4.05Å; F59-V72 HydrophobicContact CZ-CG2 4.07Å
60D93.8Very high93.9Very high41 Ų4137.1 Ų37.122%0.21920%0.195CC..  trans-79-174.4178.462.314.9000112.1S13 T31 P33 E62 A63S13-D60 CarbonylContact O-C 3.5Å; S13-D60 VanDerWaalsContact O-O 3.1Å; T31-D60 WeakPolarHBondContact OG1-CA 3.32Å; T31-D60 VanDerWaalsContact OG1-CB 3.24Å; T31-D60 WeakPolarHBondContact OG1-CB 3.21Å; P33-D60 HydrophobicContact CG-CB 4.41Å; D60-E62 VanDerWaalsContact C-N 3.27Å; D60-E62 PolarHBondContact O-N 3.04Å; D60-E62 PolarHBondContact OD1-N 2.8Å; D60-A63 WeakPolarHBondContact O-CB 3.15Å; D60-A63 PolarHBondContact O-N 3.28Å; D60-A63 WeakPolarHBondContact OD1-CB 3.25Å; D60-A63 PolarHBondContact OD1-N 3.13Å
61K91.3Very high94Very high93 Ų9336 Ų3640%0.40419%0.186SC..SBendtrans-71.1-21.9-17864.6-172.3-179.7-165.20112.8P15 Y27P15-K61 HydrophobicContact CB-CB 4.18Å; Y27-K61 HydrophobicContact CE1-CD 4Å
62E92.1Very high94.1Very high123 Ų12335.7 Ų35.758%0.57519%0.185SC*.SBendtrans-83.1-20.3175.7-66.175.9-163.900112.5D60 T64D60-E62 VanDerWaalsContact C-N 3.27Å; D60-E62 PolarHBondContact O-N 3.04Å; D60-E62 PolarHBondContact OD1-N 2.8Å; E62-T64 PolarHBondContact O-N 2.95Å
63A94.1Very high94.3Very high9 Ų932 Ų327%0.07416%0.163CC..  trans-61.9132.3-176.800000113.6R12 F59 D60R12-A63 PolarHBondContact NH2-O 3.07Å; F59-A63 HydrophobicContact CB-CB 3.69Å; F59-A63 HydrophobicContact CD1-CB 3.93Å; F59-A63 HydrophobicContact CG-CB 4.28Å; D60-A63 WeakPolarHBondContact O-CB 3.15Å; D60-A63 PolarHBondContact O-N 3.28Å; D60-A63 WeakPolarHBondContact OD1-CB 3.25Å; D60-A63 PolarHBondContact OD1-N 3.13Å
64T95.5Very high94.5Very high38 Ų3831.5 Ų31.523%0.23316%0.16CC..  trans-85.1150.7177.764.30000111.2E62 E66 L67 L68 V110E62-T64 PolarHBondContact O-N 2.95Å; T64-E66 PolarHBondContact O-N 3.32Å; T64-L67 PolarHBondContact O-N 3.47Å; T64-L67 WeakPolarHBondContact OG1-CB 3.35Å; T64-L67 PolarHBondContact OG1-N 3.4Å; T64-L68 PolarHBondContact O-N 3.26Å; T64-V110 HydrophobicContact CG2-CG1 3.37Å
65T95.9Very high94.6Very high0 Ų031 Ų310%016%0.158CC..Hα-helixtrans-61.5-28.8172.5-53.60000111.4R12 Y69 Q111 K112 I114R12-T65 PolarHBondContact NH1-OG1 2.84Å; R12-T65 PolarHBondContact NH2-OG1 2.73Å; T65-Y69 WeakPolarHBondContact O-CB 3.34Å; T65-Y69 PolarHBondContact O-N 3.49Å; T65-Q111 PolarHBondContact OG1-OE1 2.97Å; T65-K112 WeakPolarHBondContact CG2-O 3.36Å; T65-I114 HydrophobicContact CG2-CG1 4.28Å
66E95.5Very high94.6Very high74 Ų7430.8 Ų30.835%0.34616%0.157SC..Hα-helixtrans-58.1-49.3171.3-170.6161.4163.200113.5T64 Y69 N70 V110 R117T64-E66 PolarHBondContact O-N 3.32Å; E66-Y69 PolarHBondContact O-N 2.83Å; E66-N70 WeakPolarHBondContact CG-ND2 3.38Å; E66-N70 WeakPolarHBondContact O-CB 3.29Å; E66-N70 VanDerWaalsContact O-CG 3.26Å; E66-N70 PolarHBondContact O-N 2.78Å; E66-N70 PolarHBondContact O-ND2 2.77Å; E66-V110 PolarHBondContact N-O 3.24Å; E66-R117 VanDerWaalsContact CB-NH2 3.31Å; E66-R117 IonicContact OE2-NH1 2.87Å; E66-R117 IonicContact OE2-NH2 3.39Å; E66-R117 PolarHBondContact OE2-NH2 3.47Å
67L94.9Very high94.8Very high75 Ų7529 Ų2939%0.39315%0.147SC..Hα-helixtrans-60.5-49.5179.8-179.765.3000110.2F59 T64 Y69 N70 D71F59-L67 HydrophobicContact CD1-CD2 4.34Å; F59-L67 HydrophobicContact CD1-CG 4.5Å; F59-L67 HydrophobicContact CE1-CD2 4.29Å; F59-L67 HydrophobicContact CE1-CG 4.04Å; T64-L67 PolarHBondContact O-N 3.47Å; T64-L67 WeakPolarHBondContact OG1-CB 3.35Å; T64-L67 PolarHBondContact OG1-N 3.4Å; L67-Y69 VanDerWaalsContact C-N 3.3Å; L67-Y69 PolarHBondContact O-N 2.73Å; L67-N70 PolarHBondContact O-N 2.81Å; L67-D71 WeakPolarHBondContact O-CB 2.93Å; L67-D71 VanDerWaalsContact O-CG 3.29Å; L67-D71 PolarHBondContact O-N 2.82Å
68L95.5Very high94.9Very high1 Ų129.3 Ų29.31%0.00515%0.148CC..Hα-helixtrans-56.2-44.9176.4-178159.5000112.1R12 F59 T64 V72 V73 T101 I114 I309R12-L68 HydrophobicContact CB-CD1 4.35Å; R12-L68 HydrophobicContact CG-CD1 4.38Å; F59-L68 HydrophobicContact CD1-CB 4.27Å; F59-L68 HydrophobicContact CD2-CB 4.22Å; F59-L68 HydrophobicContact CD2-CD1 3.81Å; F59-L68 HydrophobicContact CD2-CG 3.92Å; F59-L68 HydrophobicContact CE1-CB 4.13Å; F59-L68 HydrophobicContact CE2-CB 4.07Å; F59-L68 HydrophobicContact CE2-CD1 4.16Å; F59-L68 HydrophobicContact CE2-CG 3.75Å; F59-L68 HydrophobicContact CG-CB 4.32Å; F59-L68 HydrophobicContact CG-CD1 4.29Å; F59-L68 HydrophobicContact CG-CG 4.47Å; F59-L68 HydrophobicContact CZ-CB 4.03Å; F59-L68 HydrophobicContact CZ-CG 4.18Å; T64-L68 PolarHBondContact O-N 3.26Å; L68-V72 PolarHBondContact O-N 2.93Å; L68-V73 HydrophobicContact CD2-CG2 4.16Å; L68-T101 HydrophobicContact CD1-CG2 4.18Å; L68-I114 HydrophobicContact CD2-CD1 3.68Å; L68-I114 HydrophobicContact CD2-CG1 4.19Å; L68-I309 HydrophobicContact CD1-CG2 4.45Å; L68-I309 HydrophobicContact CD2-CD1 4.06Å
69Y97Very high94.9Very high8 Ų829.2 Ų29.23%0.03115%0.148CC..Iπ-helixtrans-61.1-49.8178-176.1-91.6000111.4T65 E66 L67 D71 V73 Y74 I114 R117 T118 H121T65-Y69 WeakPolarHBondContact O-CB 3.34Å; T65-Y69 PolarHBondContact O-N 3.49Å; E66-Y69 PolarHBondContact O-N 2.83Å; L67-Y69 VanDerWaalsContact C-N 3.3Å; L67-Y69 PolarHBondContact O-N 2.73Å; Y69-D71 PolarHBondContact O-N 2.78Å; Y69-V73 HydrophobicContact CD2-CB 3.76Å; Y69-V73 HydrophobicContact CD2-CG1 3.83Å; Y69-V73 HydrophobicContact CD2-CG2 4.47Å; Y69-V73 HydrophobicContact CE2-CB 4.03Å; Y69-V73 HydrophobicContact CE2-CG1 3.63Å; Y69-V73 HydrophobicContact CG-CB 4.34Å; Y69-V73 CarbonylContact O-C 3.3Å; Y69-V73 PolarHBondContact O-N 3.23Å; Y69-Y74 HydrophobicContact CE1-CD2 4.09Å; Y69-Y74 PolarHBondContact O-N 2.79Å; Y69-I114 HydrophobicContact CD2-CG1 4.44Å; Y69-I114 HydrophobicContact CD2-CG2 4.27Å; Y69-I114 HydrophobicContact CE2-CG2 4.44Å; Y69-R117 HydrophobicContact CD1-CB 4.45Å; Y69-R117 HydrophobicContact CD2-CB 3.86Å; Y69-R117 HydrophobicContact CE1-CB 4.36Å; Y69-R117 HydrophobicContact CE2-CB 3.78Å; Y69-R117 HydrophobicContact CG-CB 4.21Å; Y69-R117 PolarHBondContact OH-O 3.35Å; Y69-T118 WeakPolarHBondContact OH-CA 3.45Å; Y69-H121 HydrophobicContact CE1-CB 4.46Å; Y69-H121 AromaticContact CZ-ND1 3.87Å; Y69-H121 WeakPolarHBondContact OH-CB 3.37Å; Y69-H121 PolarHBondContact OH-ND1 3.32Å
70N94.6Very high94.9Very high43 Ų4328.8 Ų28.823%0.2315%0.146CC..Iπ-helixtrans-66-36-176.9-71.9-28.1000113E66 L67E66-N70 WeakPolarHBondContact CG-ND2 3.38Å; E66-N70 WeakPolarHBondContact O-CB 3.29Å; E66-N70 VanDerWaalsContact O-CG 3.26Å; E66-N70 PolarHBondContact O-N 2.78Å; E66-N70 PolarHBondContact O-ND2 2.77Å; L67-N70 PolarHBondContact O-N 2.81Å
71D91.8Very high94.9Very high47 Ų4727.9 Ų27.925%0.25114%0.141SC..Iπ-helixtrans-77.4-38-176.3-71.8-4.1000112.3F59 L67 Y69 R493F59-D71 HydrophobicContact CE1-CB 4.49Å; F59-D71 HydrophobicContact CZ-CB 4.02Å; L67-D71 WeakPolarHBondContact O-CB 2.93Å; L67-D71 VanDerWaalsContact O-CG 3.29Å; L67-D71 PolarHBondContact O-N 2.82Å; Y69-D71 PolarHBondContact O-N 2.78Å; D71-R493 WeakPolarHBondContact OD1-CD 3.3Å; D71-R493 IonicContact OD1-NE 3.47Å; D71-R493 PolarHBondContact OD1-NE 3Å
72V92.8Very high95Very high11 Ų1127.5 Ų27.57%0.06714%0.14CC..Iπ-helixtrans-120.9-51.6-169.2-164.60000112.8V10 A57 F59 L68 I307V10-V72 HydrophobicContact CG2-CB 4.21Å; V10-V72 HydrophobicContact CG2-CG1 3.63Å; V10-V72 HydrophobicContact CG2-CG2 3.82Å; A57-V72 HydrophobicContact CB-CG2 4.15Å; F59-V72 HydrophobicContact CE2-CG2 4.05Å; F59-V72 HydrophobicContact CZ-CG2 4.07Å; L68-V72 PolarHBondContact O-N 2.93Å; V72-I307 HydrophobicContact CG1-CD1 3.7Å; V72-I307 HydrophobicContact CG1-CG1 4.24Å; V72-I307 HydrophobicContact CG1-CG2 4.04Å
73V96.6Very high95.1Very high1 Ų121.7 Ų21.71%0.00611%0.113CC..Iπ-helixtrans-77.9-33.5-170.1-1760000112.2L68 Y69 S75 L76 V77 V88 I114L68-V73 HydrophobicContact CD2-CG2 4.16Å; Y69-V73 HydrophobicContact CD2-CB 3.76Å; Y69-V73 HydrophobicContact CD2-CG1 3.83Å; Y69-V73 HydrophobicContact CD2-CG2 4.47Å; Y69-V73 HydrophobicContact CE2-CB 4.03Å; Y69-V73 HydrophobicContact CE2-CG1 3.63Å; Y69-V73 HydrophobicContact CG-CB 4.34Å; Y69-V73 CarbonylContact O-C 3.3Å; Y69-V73 PolarHBondContact O-N 3.23Å; V73-S75 VanDerWaalsContact C-N 3.31Å; V73-S75 PolarHBondContact O-N 2.88Å; V73-L76 WeakPolarHBondContact O-CA 3.04Å; V73-L76 WeakPolarHBondContact O-CB 3.27Å; V73-L76 PolarHBondContact O-N 3.08Å; V73-V77 HydrophobicContact CG1-CG2 4.09Å; V73-V77 PolarHBondContact O-N 3.28Å; V73-V88 HydrophobicContact CG1-CG2 4.17Å; V73-I114 HydrophobicContact CG1-CG2 3.93Å; V73-I114 HydrophobicContact CG2-CD1 4.13Å; V73-I114 HydrophobicContact CG2-CG1 4.4Å; V73-I114 HydrophobicContact CG2-CG2 4.31Å
74Y96.5Very high95.2Very high10 Ų1023.7 Ų23.74%0.03912%0.119CC..Hα-helixtrans-53.8-48.5179.9-172.1-76000111.3Y69 L76 V77 E78 H121 K486 A490Y69-Y74 HydrophobicContact CE1-CD2 4.09Å; Y69-Y74 PolarHBondContact O-N 2.79Å; Y74-L76 VanDerWaalsContact C-N 3.26Å; Y74-L76 PolarHBondContact O-N 2.8Å; Y74-V77 PolarHBondContact O-N 2.76Å; Y74-E78 HydrophobicContact CD1-CG 3.98Å; Y74-E78 HydrophobicContact CE1-CG 3.59Å; Y74-E78 PolarHBondContact O-N 3.44Å; Y74-H121 AromaticContact CD1-CE1 3.91Å; Y74-H121 AromaticContact CD2-CE1 3.58Å; Y74-H121 AromaticContact CD2-ND1 3.93Å; Y74-H121 AromaticContact CD2-NE2 3.96Å; Y74-H121 AromaticContact CE1-CE1 3.89Å; Y74-H121 AromaticContact CE1-NE2 3.86Å; Y74-H121 AromaticContact CE2-CD2 3.96Å; Y74-H121 AromaticContact CE2-CE1 3.57Å; Y74-H121 AromaticContact CE2-NE2 3.45Å; Y74-H121 WeakPolarHBondContact CE2-NE2 3.41Å; Y74-H121 AromaticContact CG-CE1 3.74Å; Y74-H121 AromaticContact CZ-CE1 3.71Å; Y74-H121 AromaticContact CZ-NE2 3.37Å; Y74-H121 PolarHBondContact O-CE1 3.44Å; Y74-K486 HydrophobicContact CE2-CB 4.16Å; Y74-K486 HydrophobicContact CE2-CD 4.43Å; Y74-K486 WeakPolarHBondContact OH-CB 3.36Å; Y74-A490 HydrophobicContact CD1-CB 3.32Å; Y74-A490 HydrophobicContact CE1-CB 3.7Å; Y74-A490 HydrophobicContact CG-CB 4.12Å
75S94.5Very high95.2Very high15 Ų1522.3 Ų22.311%0.10511%0.111CC..Hα-helixtrans-65.1-28.4178.4174.10000113.2V73 S79V73-S75 VanDerWaalsContact C-N 3.31Å; V73-S75 PolarHBondContact O-N 2.88Å; S75-S79 PolarHBondContact O-N 3.38Å; S75-S79 PolarHBondContact O-OG 3.21Å
76L96Very high95.3Very high1 Ų122.3 Ų22.31%0.00511%0.111CC..Hα-helixtrans-70.3-47.5174.8178.268000110.4V73 Y74 E78 S79 V80 V88 L236 K305 I307V73-L76 WeakPolarHBondContact O-CA 3.04Å; V73-L76 WeakPolarHBondContact O-CB 3.27Å; V73-L76 PolarHBondContact O-N 3.08Å; Y74-L76 VanDerWaalsContact C-N 3.26Å; Y74-L76 PolarHBondContact O-N 2.8Å; L76-E78 VanDerWaalsContact C-N 3.33Å; L76-E78 PolarHBondContact O-N 2.88Å; L76-S79 CarbonylContact O-C 3.49Å; L76-S79 WeakPolarHBondContact O-CA 3.41Å; L76-S79 VanDerWaalsContact O-CB 3.27Å; L76-S79 WeakPolarHBondContact O-CB 3.25Å; L76-S79 PolarHBondContact O-N 2.94Å; L76-V80 WeakPolarHBondContact O-CG2 3.31Å; L76-V80 PolarHBondContact O-N 2.91Å; L76-V88 HydrophobicContact CD2-CG2 3.37Å; L76-L236 HydrophobicContact CD2-CD1 4.4Å; L76-K305 HydrophobicContact CD1-CB 3.42Å; L76-K305 VanDerWaalsContact CD1-CB 3.42Å; L76-K305 WeakPolarHBondContact CD1-O 3.42Å; L76-I307 HydrophobicContact CB-CD1 3.68Å; L76-I307 HydrophobicContact CD2-CD1 3.69Å; L76-I307 HydrophobicContact CD2-CG1 4.09Å; L76-I307 HydrophobicContact CG-CD1 4.22Å
77V97.1Very high95.4Very high0 Ų018.8 Ų18.80%09%0.094CC..Hα-helixtrans-62.8-39.8179.5177.30000111.3V73 Y74 S79 V80 L81 T118 H121 I122 L236V73-V77 HydrophobicContact CG1-CG2 4.09Å; V73-V77 PolarHBondContact O-N 3.28Å; Y74-V77 PolarHBondContact O-N 2.76Å; V77-S79 VanDerWaalsContact C-N 3.28Å; V77-S79 PolarHBondContact O-N 2.77Å; V77-V80 WeakPolarHBondContact O-CB 3.23Å; V77-V80 PolarHBondContact O-N 3.08Å; V77-L81 HydrophobicContact CG1-CD1 4.26Å; V77-L81 WeakPolarHBondContact O-CG 3.27Å; V77-L81 PolarHBondContact O-N 3.4Å; V77-T118 HydrophobicContact CG2-CG2 4.06Å; V77-H121 WeakPolarHBondContact CB-ND1 3.27Å; V77-H121 HydrophobicContact CG1-CB 4.42Å; V77-H121 VanDerWaalsContact CG1-ND1 3.3Å; V77-H121 WeakPolarHBondContact CG1-ND1 3.36Å; V77-I122 HydrophobicContact CG1-CD1 4.26Å; V77-I122 HydrophobicContact CG1-CG1 3.57Å; V77-L236 HydrophobicContact CG2-CD2 4.33Å
78E95.6Very high95.6Very high12 Ų1215.2 Ų15.26%0.0568%0.075CC..Hα-helixtrans-59.4-38.8171.1-76.6-69.313200112.1Y74 L76 V80 L81 E82 H121 R483 K487Y74-E78 HydrophobicContact CD1-CG 3.98Å; Y74-E78 HydrophobicContact CE1-CG 3.59Å; Y74-E78 PolarHBondContact O-N 3.44Å; L76-E78 VanDerWaalsContact C-N 3.33Å; L76-E78 PolarHBondContact O-N 2.88Å; E78-V80 VanDerWaalsContact C-N 3.32Å; E78-V80 PolarHBondContact O-N 3.26Å; E78-L81 PolarHBondContact O-N 3.23Å; E78-E82 WeakPolarHBondContact O-CG 3.32Å; E78-E82 PolarHBondContact O-N 3.39Å; E78-H121 IonicContact OE1-CE1 3.53Å; E78-H121 IonicContact OE1-NE2 3.64Å; E78-H121 PolarHBondContact OE1-NE2 2.67Å; E78-R483 IonicContact OE1-CZ 2.89Å; E78-R483 IonicContact OE1-NH1 3.79Å; E78-R483 IonicContact OE1-NH2 3.99Å; E78-R483 PolarHBondContact OE1-NH2 3.43Å; E78-R483 IonicContact OE2-NH2 3.64Å; E78-K487 WeakPolarHBondContact OE2-CD 3.41Å; E78-K487 WeakPolarHBondContact OE2-CE 3.49Å; E78-K487 IonicContact OE2-NZ 3.8Å; E78-K487 PolarHBondContact OE2-NZ 2.84Å
79S94.8Very high95.6Very high3 Ų315.3 Ų15.32%0.0218%0.076CC..Hα-helixtrans-66.2-35.1174-60.30000112.2S75 L76 V77 L81 E82 G83 Y84 K305S75-S79 PolarHBondContact O-N 3.38Å; S75-S79 PolarHBondContact O-OG 3.21Å; L76-S79 CarbonylContact O-C 3.49Å; L76-S79 WeakPolarHBondContact O-CA 3.41Å; L76-S79 VanDerWaalsContact O-CB 3.27Å; L76-S79 WeakPolarHBondContact O-CB 3.25Å; L76-S79 PolarHBondContact O-N 2.94Å; V77-S79 VanDerWaalsContact C-N 3.28Å; V77-S79 PolarHBondContact O-N 2.77Å; S79-L81 VanDerWaalsContact C-N 3.32Å; S79-E82 WeakPolarHBondContact O-CB 3.49Å; S79-E82 PolarHBondContact O-N 2.68Å; S79-E82 VanDerWaalsContact O-N 3.16Å; S79-G83 PolarHBondContact O-N 2.88Å; S79-Y84 WeakPolarHBondContact O-CB 3.22Å; S79-Y84 VanDerWaalsContact O-CD2 3.3Å; S79-Y84 WeakPolarHBondContact O-CD2 3.47Å; S79-Y84 PolarHBondContact O-N 3.38Å; S79-Y84 VanDerWaalsContact O-N 3.1Å; S79-K305 VanDerWaalsContact CB-NZ 3.27Å; S79-K305 PolarHBondContact OG-NZ 3.16Å
80V96.7Very high95.6Very high0 Ų014.9 Ų14.90%07%0.074CC..Hα-helixtrans-64.3-41.2176.4172.30000110.7L76 V77 E78 E82 G83 Y84 L219 M221 A234 L236L76-V80 WeakPolarHBondContact O-CG2 3.31Å; L76-V80 PolarHBondContact O-N 2.91Å; V77-V80 WeakPolarHBondContact O-CB 3.23Å; V77-V80 PolarHBondContact O-N 3.08Å; E78-V80 VanDerWaalsContact C-N 3.32Å; E78-V80 PolarHBondContact O-N 3.26Å; V80-E82 PolarHBondContact O-N 2.81Å; V80-G83 PolarHBondContact O-N 3.1Å; V80-Y84 WeakPolarHBondContact CA-O 3.39Å; V80-L219 HydrophobicContact CG1-CD1 3.94Å; V80-L219 HydrophobicContact CG1-CD2 4.19Å; V80-M221 WeakPolarHBondContact O-CE 3.38Å; V80-A234 HydrophobicContact CG1-CB 3.88Å; V80-A234 WeakPolarHBondContact O-CB 3.43Å; V80-L236 HydrophobicContact CG1-CB 4.06Å; V80-L236 HydrophobicContact CG2-CB 4.25Å; V80-L236 HydrophobicContact CG2-CD1 4.18Å
81L94.9Very high95.7Very high21 Ų2113.5 Ų13.511%0.117%0.066CC..Hα-helixtrans-67-12.8174.9-67.1161.4000113.6V77 E78 S79 I122 A125 I126 F134 L219V77-L81 HydrophobicContact CG1-CD1 4.26Å; V77-L81 WeakPolarHBondContact O-CG 3.27Å; V77-L81 PolarHBondContact O-N 3.4Å; E78-L81 PolarHBondContact O-N 3.23Å; S79-L81 VanDerWaalsContact C-N 3.32Å; L81-I122 HydrophobicContact CD2-CG2 4.36Å; L81-A125 HydrophobicContact CD1-CB 3.29Å; L81-A125 HydrophobicContact CD2-CB 3.99Å; L81-A125 HydrophobicContact CG-CB 4.26Å; L81-I126 HydrophobicContact CD2-CG1 4.17Å; L81-F134 HydrophobicContact CD2-CE1 4.15Å; L81-L219 HydrophobicContact CD2-CD2 4.06Å
82E93Very high95.8Very high86 Ų8611.2 Ų11.240%0.4025%0.054SC..THydrogen-bonded Turntrans-92.1-7.8172.4-69.6168.3-176.200113.1E78 S79 V80 Y84E78-E82 WeakPolarHBondContact O-CG 3.32Å; E78-E82 PolarHBondContact O-N 3.39Å; S79-E82 WeakPolarHBondContact O-CB 3.49Å; S79-E82 PolarHBondContact O-N 2.68Å; S79-E82 VanDerWaalsContact O-N 3.16Å; V80-E82 PolarHBondContact O-N 2.81Å; E82-Y84 HydrophobicContact CB-CD2 4.17Å; E82-Y84 HydrophobicContact CB-CE2 4.35Å
83G93.7Very high95.8Very high0 Ų011.4 Ų11.40%05%0.054CC..THydrogen-bonded Turntrans104.811.4-178.300000115.7S79 V80 T233 I341 N342S79-G83 PolarHBondContact O-N 2.88Å; V80-G83 PolarHBondContact O-N 3.1Å; G83-T233 VanDerWaalsContact O-O 3.13Å; G83-I341 WeakPolarHBondContact O-CA 3.48Å; G83-N342 PolarHBondContact O-N 3.5Å; G83-N342 PolarHBondContact O-ND2 2.86Å
84Y95.6Very high95.5Very high51 Ų5113.6 Ų13.620%0.27%0.067CC..BIsolated β-bridgetrans-86.3146.6171.7-66.9-84.6000111.5S79 V80 E82 A234 K305 P339 R340 I341S79-Y84 WeakPolarHBondContact O-CB 3.22Å; S79-Y84 VanDerWaalsContact O-CD2 3.3Å; S79-Y84 WeakPolarHBondContact O-CD2 3.47Å; S79-Y84 PolarHBondContact O-N 3.38Å; S79-Y84 VanDerWaalsContact O-N 3.1Å; V80-Y84 WeakPolarHBondContact CA-O 3.39Å; E82-Y84 HydrophobicContact CB-CD2 4.17Å; E82-Y84 HydrophobicContact CB-CE2 4.35Å; Y84-A234 WeakPolarHBondContact O-CB 3.36Å; Y84-K305 HydrophobicContact CG-CD 4.38Å; Y84-P339 HydrophobicContact CD1-CB 4Å; Y84-P339 HydrophobicContact CE1-CB 4.42Å; Y84-R340 WeakPolarHBondContact CD1-O 3.39Å; Y84-I341 HydrophobicContact CD1-CG1 4.35Å; Y84-I341 HydrophobicContact CD2-CG1 4.18Å; Y84-I341 HydrophobicContact CE1-CG1 3.86Å; Y84-I341 HydrophobicContact CE2-CD1 4.12Å; Y84-I341 HydrophobicContact CE2-CG1 3.65Å; Y84-I341 VanDerWaalsContact CZ-CG1 3.45Å
85N96.5Very high95.2Very high10 Ų1015.4 Ų15.45%0.0539%0.089CC..  trans-71.4143.3164.5-61.4-29.6000110.3K235 D298 N303 T304 K305 N342N85-K235 CarbonylContact C-O 3.57Å; N85-K235 WeakPolarHBondContact CA-O 3.41Å; N85-K235 PolarHBondContact OD1-N 3.34Å; N85-D298 PolarHBondContact ND2-OD2 3.3Å; N85-D298 VanDerWaalsContact ND2-OD2 3.15Å; N85-N303 WeakPolarHBondContact CB-O 3.48Å; N85-N303 PolarHBondContact ND2-O 3.04Å; N85-N303 VanDerWaalsContact ND2-O 3.08Å; N85-T304 HydrophobicContact CB-CG2 4.12Å; N85-T304 VanDerWaalsContact CB-OG1 3.3Å; N85-T304 WeakPolarHBondContact CB-OG1 3.18Å; N85-K305 PolarHBondContact O-N 3.45Å; N85-N342 PolarHBondContact OD1-ND2 3.41Å
86G97.4Very high95.2Very high0 Ų014.8 Ų14.80%09%0.085CC..EExtended strand (participates in β ladder)trans-126.4146.5177.400000112K235 L236 H237 K305G86-K235 PolarHBondContact N-O 3.06Å; G86-L236 WeakPolarHBondContact O-CA 3.5Å; G86-H237 PolarHBondContact O-N 3.47Å; G86-K305 CarbonylContact C-O 3.57Å; G86-K305 WeakPolarHBondContact CA-O 3.22Å
87T97.9Very high95.1Very high0 Ų015.5 Ų15.50%09%0.092CC..EExtended strand (participates in β ladder)trans-139.6132.1169.1-64.20000109.9F89 H237 V239 S299 T304 K305 T306 I307T87-F89 HydrophobicContact CG2-CD1 4.01Å; T87-H237 CarbonylContact C-O 3.37Å; T87-H237 WeakPolarHBondContact CA-O 3.34Å; T87-H237 HydrophobicContact CG2-CB 4.04Å; T87-V239 HydrophobicContact CG2-CG2 4.48Å; T87-S299 PolarHBondContact OG1-OG 2.94Å; T87-T304 WeakPolarHBondContact OG1-CG2 3.3Å; T87-K305 PolarHBondContact N-O 3.29Å; T87-T306 HydrophobicContact CG2-CG2 4.35Å; T87-T306 CarbonylContact O-C 3.6Å; T87-T306 WeakPolarHBondContact O-CA 3.28Å; T87-I307 PolarHBondContact O-N 2.69Å
88V98.1Very high95Very high0 Ų016.1 Ų16.10%010%0.095CC..EExtended strand (participates in β ladder)trans-119.4121.3166.2-174.40000107V73 L76 M102 I114 H237 L238 V239 I307 I309V73-V88 HydrophobicContact CG1-CG2 4.17Å; L76-V88 HydrophobicContact CD2-CG2 3.37Å; V88-M102 HydrophobicContact CG1-CE 4.48Å; V88-M102 HydrophobicContact CG1-SD 4.23Å; V88-I114 HydrophobicContact CG1-CD1 4.4Å; V88-H237 PolarHBondContact N-O 3.1Å; V88-L238 HydrophobicContact CB-CD2 4.12Å; V88-L238 HydrophobicContact CG2-CD2 4.19Å; V88-V239 PolarHBondContact O-N 3.01Å; V88-I307 WeakPolarHBondContact CA-O 3.04Å; V88-I307 HydrophobicContact CG2-CB 4.46Å; V88-I309 HydrophobicContact CG1-CD1 3.63Å; V88-I309 HydrophobicContact CG1-CG1 4.26Å
89F96.2Very high94.9Very high2 Ų218 Ų181%0.00911%0.109CC..EExtended strand (participates in β ladder)trans-127.5133.4173.467.3-96.2000112T87 V239 L241 L300 T306 I307 M308 I309T87-F89 HydrophobicContact CG2-CD1 4.01Å; F89-V239 WeakPolarHBondContact CA-O 3.34Å; F89-V239 HydrophobicContact CB-CB 3.63Å; F89-V239 HydrophobicContact CB-CG1 4.12Å; F89-V239 HydrophobicContact CB-CG2 4.3Å; F89-L241 HydrophobicContact CD2-CD1 3.81Å; F89-L241 HydrophobicContact CE2-CD1 4.46Å; F89-L300 HydrophobicContact CE1-CD2 4.11Å; F89-L300 HydrophobicContact CZ-CD2 4.29Å; F89-T306 HydrophobicContact CD1-CG2 3.94Å; F89-T306 HydrophobicContact CE1-CG2 3.46Å; F89-T306 VanDerWaalsContact CE1-CG2 3.46Å; F89-I307 PolarHBondContact N-O 3.32Å; F89-M308 HydrophobicContact CD2-CB 4.41Å; F89-M308 HydrophobicContact CD2-CG 4.12Å; F89-M308 HydrophobicContact CE1-CB 4.15Å; F89-M308 HydrophobicContact CE2-CB 3.72Å; F89-M308 HydrophobicContact CE2-CG 3.42Å; F89-M308 VanDerWaalsContact CE2-CG 3.42Å; F89-M308 HydrophobicContact CE2-SD 3.89Å; F89-M308 HydrophobicContact CZ-CB 3.57Å; F89-M308 HydrophobicContact CZ-CG 3.78Å; F89-M308 HydrophobicContact CZ-SD 4.15Å; F89-I309 PolarHBondContact O-N 2.78Å
90A97.1Very high94.9Very high0 Ų021.9 Ų21.90%013%0.126CC..EExtended strand (participates in β ladder)trans-93.4133.4174.400000110.4K98 M102 V239 L241 I309A90-K98 HydrophobicContact CB-CB 3.95Å; A90-K98 HydrophobicContact CB-CG 4.26Å; A90-M102 HydrophobicContact CB-CG 3.76Å; A90-M102 HydrophobicContact CB-SD 4.16Å; A90-V239 PolarHBondContact N-O 3.22Å; A90-L241 WeakPolarHBondContact O-CB 3.27Å; A90-L241 WeakPolarHBondContact O-CG 3.47Å; A90-L241 PolarHBondContact O-N 2.84Å; A90-I309 CarbonylContact C-O 3.59Å; A90-I309 WeakPolarHBondContact CA-O 3.35Å
91Y96.2Very high94.9Very high13 Ų1322 Ų225%0.05113%0.126CC..EExtended strand (participates in β ladder)trans-135.2145.1-176.6-180-87.4000111.1L241 S244 L267 M308 I309 A310 C311 T325 Y328Y91-L241 HydrophobicContact CD2-CD1 3.81Å; Y91-L241 HydrophobicContact CG-CD1 4.48Å; Y91-S244 WeakPolarHBondContact OH-CB 3.4Å; Y91-L267 HydrophobicContact CD2-CD2 4.44Å; Y91-L267 HydrophobicContact CE2-CD2 4.07Å; Y91-M308 HydrophobicContact CD1-CE 3.75Å; Y91-M308 HydrophobicContact CG-CE 3.91Å; Y91-I309 PolarHBondContact N-O 2.84Å; Y91-A310 WeakPolarHBondContact O-CA 3.46Å; Y91-C311 PolarHBondContact O-N 3.27Å; Y91-T325 HydrophobicContact CD1-CG2 3.86Å; Y91-T325 HydrophobicContact CE1-CG2 4.06Å; Y91-Y328 HydrophobicContact CD1-CD1 4.14Å; Y91-Y328 HydrophobicContact CD1-CE1 4.5Å; Y91-Y328 HydrophobicContact CD2-CE1 4.28Å; Y91-Y328 AromaticContact CE1-CD1 3.91Å; Y91-Y328 HydrophobicContact CE1-CD1 3.91Å; Y91-Y328 HydrophobicContact CE1-CD2 4.42Å; Y91-Y328 HydrophobicContact CE1-CE1 4.4Å; Y91-Y328 AromaticContact CE1-CG 3.91Å; Y91-Y328 HydrophobicContact CE1-CG 3.91Å; Y91-Y328 HydrophobicContact CE2-CD1 4.42Å; Y91-Y328 HydrophobicContact CE2-CE1 4.12Å; Y91-Y328 HydrophobicContact CE2-CE2 4.28Å; Y91-Y328 HydrophobicContact CG-CE1 4.46Å; Y91-Y328 AromaticContact CZ-CD2 3.99Å; Y91-Y328 AromaticContact CZ-CG 3.93Å
92G94.8Very high95Very high0 Ų021.1 Ų21.10%012%0.122CC..SBendtrans145.1177179.700000112.4K98 S244G92-K98 WeakPolarHBondContact O-CD 3.26Å; G92-K98 WeakPolarHBondContact O-CE 3.41Å; G92-K98 PolarHBondContact O-NZ 2.88Å; G92-S244 WeakPolarHBondContact CA-OG 3.5Å; G92-S244 PolarHBondContact O-N 2.77Å; G92-S244 VanDerWaalsContact O-N 3.14Å; G92-S244 PolarHBondContact O-OG 2.74Å
93Q92.6Very high95Very high15 Ų1518.8 Ų18.87%0.0711%0.111CC..SBendtrans-64.5161.7-17967.2169.191.400113.5G95 S96 K98 S244 E245 N318 E321Q93-G95 PolarHBondContact O-N 3.16Å; Q93-S96 WeakPolarHBondContact O-CB 3.35Å; Q93-S96 PolarHBondContact O-N 3.45Å; Q93-S96 VanDerWaalsContact O-N 3.12Å; Q93-S96 PolarHBondContact O-OG 3.41Å; Q93-K98 PolarHBondContact O-NZ 3.31Å; Q93-S244 PolarHBondContact N-OG 3.3Å; Q93-E245 VanDerWaalsContact CA-OE2 3.31Å; Q93-E245 WeakPolarHBondContact CA-OE2 3.3Å; Q93-E245 HydrophobicContact CB-CB 4.11Å; Q93-N318 VanDerWaalsContact NE2-CG 3.28Å; Q93-N318 PolarHBondContact NE2-OD1 2.71Å; Q93-N318 VanDerWaalsContact OE1-CB 3.24Å; Q93-N318 VanDerWaalsContact OE1-CG 3.3Å; Q93-N318 PolarHBondContact OE1-OD1 3.4Å; Q93-E321 HydrophobicContact CB-CB 4.17Å; Q93-E321 HydrophobicContact CG-CB 4.43Å
94T90.9Very high94.9Very high47 Ų4719.6 Ų19.629%0.28812%0.119SC..THydrogen-bonded Turntrans-55.6135.9168.2-62.70000110.5S96 E245T94-S96 VanDerWaalsContact C-N 3.27Å; T94-S96 PolarHBondContact O-N 2.93Å; T94-E245 WeakPolarHBondContact CB-OE1 3.41Å; T94-E245 PolarHBondContact N-OE2 3.44Å; T94-E245 VanDerWaalsContact OG1-CD 3.3Å; T94-E245 PolarHBondContact OG1-OE1 2.84Å; T94-E245 PolarHBondContact OG1-OE2 3.45Å
95G90.4Very high94.7Very high48 Ų4819.1 Ų19.150%0.49512%0.122SC..THydrogen-bonded Turntrans73.18.3-176.600000115.2R14 Q93 G97R14-G95 PolarHBondContact NE-O 3.25Å; R14-G95 PolarHBondContact NH2-O 3.21Å; Q93-G95 PolarHBondContact O-N 3.16Å; G95-G97 VanDerWaalsContact C-N 3.29Å; G95-G97 PolarHBondContact O-N 3.4Å
96S93.2Very high94Very high2 Ų224.8 Ų24.81%0.01415%0.153CC..SBendtrans-80.1-5.1174.671.90000114.8Q93 T94 C311Q93-S96 WeakPolarHBondContact O-CB 3.35Å; Q93-S96 PolarHBondContact O-N 3.45Å; Q93-S96 VanDerWaalsContact O-N 3.12Å; Q93-S96 PolarHBondContact O-OG 3.41Å; T94-S96 VanDerWaalsContact C-N 3.27Å; T94-S96 PolarHBondContact O-N 2.93Å; S96-C311 WeakPolarHBondContact CB-O 3.45Å; S96-C311 VanDerWaalsContact OG-CB 3.28Å; S96-C311 WeakPolarHBondContact OG-CB 3.39Å; S96-C311 PolarHBondContact OG-O 2.92Å
97G93.7Very high93.5Very high16 Ų1632.5 Ų32.517%0.16519%0.194CC..SBendtrans101.915.9178.100000115.7G95 F100 T101G95-G97 VanDerWaalsContact C-N 3.29Å; G95-G97 PolarHBondContact O-N 3.4Å; G97-F100 PolarHBondContact O-N 3.23Å; G97-T101 WeakPolarHBondContact O-CB 3.25Å; G97-T101 PolarHBondContact O-N 3.39Å; G97-T101 PolarHBondContact O-OG1 3.44Å
98K95.7Very high93.1Very high13 Ų1339.5 Ų39.56%0.05722%0.22CC..Hα-helixtrans-55.7-61.1175.3-59.6-173.9-62.7-73.60112.8A90 G92 Q93 F100 T101 M102 D240 L241 C311A90-K98 HydrophobicContact CB-CB 3.95Å; A90-K98 HydrophobicContact CB-CG 4.26Å; G92-K98 WeakPolarHBondContact O-CD 3.26Å; G92-K98 WeakPolarHBondContact O-CE 3.41Å; G92-K98 PolarHBondContact O-NZ 2.88Å; Q93-K98 PolarHBondContact O-NZ 3.31Å; K98-F100 VanDerWaalsContact C-N 3.3Å; K98-F100 PolarHBondContact O-N 3.18Å; K98-T101 WeakPolarHBondContact O-CB 3.36Å; K98-T101 PolarHBondContact O-N 3.48Å; K98-M102 PolarHBondContact O-N 3.43Å; K98-D240 WeakPolarHBondContact CB-OD1 3.42Å; K98-L241 WeakPolarHBondContact CE-O 3.43Å; K98-C311 HydrophobicContact CG-CB 3.98Å
99S93.8Very high92.7Very high51 Ų5144 Ų4436%0.35725%0.249SC..Hα-helixtrans-65-33.7179.4-44.10000112.1T101 M102 Q103 G104 D240S99-T101 VanDerWaalsContact C-N 3.3Å; S99-T101 PolarHBondContact O-N 3.42Å; S99-M102 PolarHBondContact O-N 3.49Å; S99-Q103 WeakPolarHBondContact O-CB 2.82Å; S99-Q103 PolarHBondContact O-N 2.9Å; S99-G104 PolarHBondContact O-N 3.09Å; S99-D240 WeakPolarHBondContact CB-OD2 3.3Å; S99-D240 PolarHBondContact OG-OD2 3.44Å
100F94.4Very high92.6Very high85 Ų8546.8 Ų46.837%0.37327%0.267SS..Hα-helixtrans-61.2-38.4170.9-178.2-87.9000112.1G97 K98 G104 P105 Q111G97-F100 PolarHBondContact O-N 3.23Å; K98-F100 VanDerWaalsContact C-N 3.3Å; K98-F100 PolarHBondContact O-N 3.18Å; F100-G104 WeakPolarHBondContact O-CA 3.42Å; F100-G104 PolarHBondContact O-N 2.94Å; F100-P105 HydrophobicContact CE2-CG 4.12Å; F100-Q111 HydrophobicContact CZ-CB 3.93Å; F100-Q111 HydrophobicContact CZ-CG 4.05Å
101T96.7Very high92.5Very high1 Ų147.7 Ų47.71%0.00627%0.271CS..Hα-helixtrans-73.7-41.9178-57.80000111.7R12 L68 G97 K98 S99 I114 I309R12-T101 WeakPolarHBondContact CD-OG1 3.23Å; R12-T101 PolarHBondContact NH1-OG1 3.03Å; L68-T101 HydrophobicContact CD1-CG2 4.18Å; G97-T101 WeakPolarHBondContact O-CB 3.25Å; G97-T101 PolarHBondContact O-N 3.39Å; G97-T101 PolarHBondContact O-OG1 3.44Å; K98-T101 WeakPolarHBondContact O-CB 3.36Å; K98-T101 PolarHBondContact O-N 3.48Å; S99-T101 VanDerWaalsContact C-N 3.3Å; S99-T101 PolarHBondContact O-N 3.42Å; T101-I114 HydrophobicContact CG2-CD1 3.63Å; T101-I114 HydrophobicContact CG2-CG1 4.39Å; T101-I114 WeakPolarHBondContact O-CG1 3.23Å; T101-I114 PolarHBondContact O-N 3.19Å; T101-I309 HydrophobicContact CG2-CD1 4.18Å; T101-I309 HydrophobicContact CG2-CG2 4.24Å
102M96.8Very high92.4Very high3 Ų349 Ų492%0.01528%0.277CS..Hα-helixtrans-76.5-47-177.6-66.4-58.6-70.500112.8V88 A90 K98 S99 G113 I114 V115 L238 D240V88-M102 HydrophobicContact CG1-CE 4.48Å; V88-M102 HydrophobicContact CG1-SD 4.23Å; A90-M102 HydrophobicContact CB-CG 3.76Å; A90-M102 HydrophobicContact CB-SD 4.16Å; K98-M102 PolarHBondContact O-N 3.43Å; S99-M102 PolarHBondContact O-N 3.49Å; M102-G113 CarbonylContact O-C 3.59Å; M102-I114 PolarHBondContact O-N 3.44Å; M102-I114 VanDerWaalsContact O-N 3.09Å; M102-I114 HydrophobicContact SD-CB 4.44Å; M102-I114 HydrophobicContact SD-CD1 4.11Å; M102-V115 HydrophobicContact CB-CG2 4.28Å; M102-V115 HydrophobicContact CE-CG2 3.98Å; M102-V115 VanDerWaalsContact O-CB 3.3Å; M102-V115 WeakPolarHBondContact O-CB 3.23Å; M102-V115 VanDerWaalsContact O-CG2 3.23Å; M102-V115 WeakPolarHBondContact O-CG2 3.2Å; M102-V115 PolarHBondContact O-N 2.68Å; M102-L238 HydrophobicContact CE-CB 3.87Å; M102-L238 HydrophobicContact CE-CD2 4.48Å; M102-D240 HydrophobicContact CG-CB 4.4Å
103Q93.7Very high92.5Very high38 Ų3849 Ų4918%0.17828%0.277CS..THydrogen-bonded Turntrans-99.9-44.8-175.6-63.61672.900111.9S99 G113 M194S99-Q103 WeakPolarHBondContact O-CB 2.82Å; S99-Q103 PolarHBondContact O-N 2.9Å; Q103-G113 WeakPolarHBondContact O-CA 3.03Å; Q103-G113 PolarHBondContact O-N 3.32Å; Q103-M194 HydrophobicContact CG-SD 4.44Å
104G91.6Very high92.7Very high16 Ų1648.3 Ų48.317%0.16527%0.274CS..  trans66170.9-175.600000113.5S99 F100S99-G104 PolarHBondContact O-N 3.09Å; F100-G104 WeakPolarHBondContact O-CA 3.42Å; F100-G104 PolarHBondContact O-N 2.94Å
105P90.7Very high93Very high41 Ų4146.4 Ų46.427%0.26626%0.262SS..  trans-74.3138.4172.829.8-36.9000112F100 N107 W108 Q111F100-P105 HydrophobicContact CE2-CG 4.12Å; P105-N107 VanDerWaalsContact C-N 3.33Å; P105-N107 PolarHBondContact O-N 3.26Å; P105-W108 HydrophobicContact CB-CB 4.37Å; P105-W108 HydrophobicContact CG-CB 3.77Å; P105-W108 HydrophobicContact CG-CE3 4.35Å; P105-Q111 WeakPolarHBondContact CD-O 3.32Å; P105-Q111 HydrophobicContact CG-CB 3.89Å
106D82.9Confident93.3Very high130 Ų13044.5 Ų44.570%0.69524%0.241SC*.THydrogen-bonded Turntrans-64.7-35.8177.6-66.1-36000112.5W108D106-W108 PolarHBondContact O-N 3.04Å
107N87Confident93.5Very high162 Ų16245.6 Ų45.687%0.86624%0.244SC*.THydrogen-bonded Turntrans-86.5-2.7-171.7-66.3-16.6000114.8P105P105-N107 VanDerWaalsContact C-N 3.33Å; P105-N107 PolarHBondContact O-N 3.26Å
108W88.7Confident93.6Very high146 Ų14644.8 Ų44.855%0.55324%0.237SC*.  trans-123.492.7-174.3-163.94.9000110.8P105 D106 V110 Q111 K112P105-W108 HydrophobicContact CB-CB 4.37Å; P105-W108 HydrophobicContact CG-CB 3.77Å; P105-W108 HydrophobicContact CG-CE3 4.35Å; D106-W108 PolarHBondContact O-N 3.04Å; W108-V110 VanDerWaalsContact C-N 3.3Å; W108-V110 PolarHBondContact O-N 3.03Å; W108-V110 VanDerWaalsContact O-N 3.16Å; W108-Q111 HydrophobicContact CB-CB 4.27Å; W108-Q111 HydrophobicContact CD2-CB 3.88Å; W108-Q111 HydrophobicContact CD2-CG 3.57Å; W108-Q111 HydrophobicContact CE3-CB 3.91Å; W108-Q111 HydrophobicContact CE3-CG 3.59Å; W108-Q111 HydrophobicContact CG-CB 4.05Å; W108-Q111 HydrophobicContact CG-CG 4.17Å; W108-Q111 HydrophobicContact CH2-CG 4.1Å; W108-Q111 HydrophobicContact CZ2-CG 4.08Å; W108-Q111 HydrophobicContact CZ3-CG 3.86Å; W108-Q111 CarbonylContact O-C 3.54Å; W108-Q111 WeakPolarHBondContact O-CA 3.43Å; W108-Q111 PolarHBondContact O-N 3.02Å; W108-K112 PolarHBondContact O-N 3.16Å
109P90.7Very high93.7Very high95 Ų9544.2 Ų44.262%0.61723%0.234SC*.G310 helixtrans-54.3-41.7-171.3-29.635.3000114Q111 K112 R117P109-Q111 VanDerWaalsContact C-N 3.26Å; P109-Q111 PolarHBondContact O-N 3.23Å; P109-K112 WeakPolarHBondContact O-CB 3.33Å; P109-K112 PolarHBondContact O-N 3.44Å; P109-R117 PolarHBondContact O-NH2 3.05Å
110V92.9Very high93.8Very high61 Ų6145.5 Ų45.537%0.3724%0.235SC..G310 helixtrans-66.1-28.1179.9179.50000112.3T64 E66 W108 R117T64-V110 HydrophobicContact CG2-CG1 3.37Å; E66-V110 PolarHBondContact N-O 3.24Å; W108-V110 VanDerWaalsContact C-N 3.3Å; W108-V110 PolarHBondContact O-N 3.03Å; W108-V110 VanDerWaalsContact O-N 3.16Å; V110-R117 PolarHBondContact O-NH2 2.91Å
111Q94.5Very high93.8Very high19 Ų1941.9 Ų41.99%0.08922%0.219CC..G310 helixtrans-101.74.1177.6-66.2-67.7-0.300113.6T65 F100 P105 W108 P109 G113T65-Q111 PolarHBondContact OG1-OE1 2.97Å; F100-Q111 HydrophobicContact CZ-CB 3.93Å; F100-Q111 HydrophobicContact CZ-CG 4.05Å; P105-Q111 WeakPolarHBondContact CD-O 3.32Å; P105-Q111 HydrophobicContact CG-CB 3.89Å; W108-Q111 HydrophobicContact CB-CB 4.27Å; W108-Q111 HydrophobicContact CD2-CB 3.88Å; W108-Q111 HydrophobicContact CD2-CG 3.57Å; W108-Q111 HydrophobicContact CE3-CB 3.91Å; W108-Q111 HydrophobicContact CE3-CG 3.59Å; W108-Q111 HydrophobicContact CG-CB 4.05Å; W108-Q111 HydrophobicContact CG-CG 4.17Å; W108-Q111 HydrophobicContact CH2-CG 4.1Å; W108-Q111 HydrophobicContact CZ2-CG 4.08Å; W108-Q111 HydrophobicContact CZ3-CG 3.86Å; W108-Q111 CarbonylContact O-C 3.54Å; W108-Q111 WeakPolarHBondContact O-CA 3.43Å; W108-Q111 PolarHBondContact O-N 3.02Å; P109-Q111 VanDerWaalsContact C-N 3.26Å; P109-Q111 PolarHBondContact O-N 3.23Å; Q111-G113 PolarHBondContact O-N 2.81Å
112K95.4Very high93.8Very high41 Ų4141.9 Ų41.918%0.17822%0.218CC..  trans-46.4132.1171.8-174.7167.8-176.5167.30109.7T65 W108 P109 P116 R117 E120 E187T65-K112 WeakPolarHBondContact CG2-O 3.36Å; W108-K112 PolarHBondContact O-N 3.16Å; P109-K112 WeakPolarHBondContact O-CB 3.33Å; P109-K112 PolarHBondContact O-N 3.44Å; K112-P116 HydrophobicContact CD-CG 4.39Å; K112-P116 HydrophobicContact CG-CB 4.42Å; K112-P116 HydrophobicContact CG-CG 3.76Å; K112-R117 HydrophobicContact CB-CG 4.44Å; K112-R117 HydrophobicContact CG-CG 4.2Å; K112-R117 WeakPolarHBondContact O-CD 3.41Å; K112-R117 PolarHBondContact O-NE 3.47Å; K112-E120 WeakPolarHBondContact CE-OE1 3.42Å; K112-E120 IonicContact NZ-OE1 2.84Å; K112-E120 PolarHBondContact NZ-OE1 3.36Å; K112-E187 IonicContact NZ-OE1 3.86Å; K112-E187 PolarHBondContact NZ-OE1 3.37Å
113G96.4Very high93.7Very high0 Ų042.8 Ų42.80%022%0.223CC..  trans-68.8170.7-170.600000114.2M102 Q103 Q111 V115 P116 R117M102-G113 CarbonylContact O-C 3.59Å; Q103-G113 WeakPolarHBondContact O-CA 3.03Å; Q103-G113 PolarHBondContact O-N 3.32Å; Q111-G113 PolarHBondContact O-N 2.81Å; G113-V115 PolarHBondContact O-N 2.99Å; G113-P116 WeakPolarHBondContact O-CD 3.38Å; G113-R117 WeakPolarHBondContact O-CB 3.44Å; G113-R117 WeakPolarHBondContact O-CG 3.14Å; G113-R117 PolarHBondContact O-N 3.3Å
114I97.6Very high93.7Very high0 Ų042.6 Ų42.60%022%0.221CC..Hα-helixtrans-58.8-45.6176.6-68.3168.4000111.8T65 L68 Y69 V73 V88 T101 M102 R117 T118 L238 I309T65-I114 HydrophobicContact CG2-CG1 4.28Å; L68-I114 HydrophobicContact CD2-CD1 3.68Å; L68-I114 HydrophobicContact CD2-CG1 4.19Å; Y69-I114 HydrophobicContact CD2-CG1 4.44Å; Y69-I114 HydrophobicContact CD2-CG2 4.27Å; Y69-I114 HydrophobicContact CE2-CG2 4.44Å; V73-I114 HydrophobicContact CG1-CG2 3.93Å; V73-I114 HydrophobicContact CG2-CD1 4.13Å; V73-I114 HydrophobicContact CG2-CG1 4.4Å; V73-I114 HydrophobicContact CG2-CG2 4.31Å; V88-I114 HydrophobicContact CG1-CD1 4.4Å; T101-I114 HydrophobicContact CG2-CD1 3.63Å; T101-I114 HydrophobicContact CG2-CG1 4.39Å; T101-I114 WeakPolarHBondContact O-CG1 3.23Å; T101-I114 PolarHBondContact O-N 3.19Å; M102-I114 PolarHBondContact O-N 3.44Å; M102-I114 VanDerWaalsContact O-N 3.09Å; M102-I114 HydrophobicContact SD-CB 4.44Å; M102-I114 HydrophobicContact SD-CD1 4.11Å; I114-R117 PolarHBondContact O-N 2.91Å; I114-T118 WeakPolarHBondContact O-CB 3.41Å; I114-T118 PolarHBondContact O-N 3.49Å; I114-T118 PolarHBondContact O-OG1 3.34Å; I114-T118 VanDerWaalsContact O-OG1 3.05Å; I114-L238 HydrophobicContact CG2-CD2 4.47Å; I114-I309 HydrophobicContact CD1-CD1 3.24Å
115V97.1Very high93.8Very high6 Ų641.8 Ų41.84%0.03621%0.214CC..Hα-helixtrans-58-57.8-175.3175.60000111.8M102 G113 R117 T118 F119 L190 L238M102-V115 HydrophobicContact CB-CG2 4.28Å; M102-V115 HydrophobicContact CE-CG2 3.98Å; M102-V115 VanDerWaalsContact O-CB 3.3Å; M102-V115 WeakPolarHBondContact O-CB 3.23Å; M102-V115 VanDerWaalsContact O-CG2 3.23Å; M102-V115 WeakPolarHBondContact O-CG2 3.2Å; M102-V115 PolarHBondContact O-N 2.68Å; G113-V115 PolarHBondContact O-N 2.99Å; V115-R117 VanDerWaalsContact C-N 3.33Å; V115-R117 PolarHBondContact O-N 3.26Å; V115-T118 WeakPolarHBondContact O-CB 3.33Å; V115-T118 PolarHBondContact O-N 2.85Å; V115-F119 HydrophobicContact CG1-CE1 3.91Å; V115-F119 HydrophobicContact CG1-CE2 3.87Å; V115-F119 HydrophobicContact CG1-CZ 3.35Å; V115-F119 WeakPolarHBondContact O-CD1 3.39Å; V115-F119 PolarHBondContact O-N 2.82Å; V115-L190 HydrophobicContact CG1-CD1 4.09Å; V115-L190 HydrophobicContact CG1-CD2 3.86Å; V115-L238 HydrophobicContact CB-CD1 4.26Å; V115-L238 HydrophobicContact CG1-CD1 4.07Å; V115-L238 HydrophobicContact CG2-CB 4.04Å; V115-L238 HydrophobicContact CG2-CD1 4Å
116P96.3Very high93.8Very high9 Ų940 Ų406%0.05820%0.202CC..Hα-helixtrans-71.9-26.2-178.633.5-41000112.9K112 G113 F119 E120K112-P116 HydrophobicContact CD-CG 4.39Å; K112-P116 HydrophobicContact CG-CB 4.42Å; K112-P116 HydrophobicContact CG-CG 3.76Å; G113-P116 WeakPolarHBondContact O-CD 3.38Å; P116-F119 HydrophobicContact CB-CD2 4.4Å; P116-F119 WeakPolarHBondContact O-CB 3.4Å; P116-F119 PolarHBondContact O-N 3.37Å; P116-E120 PolarHBondContact O-N 2.83Å
117R96.1Very high94.2Very high24 Ų2434.3 Ų34.39%0.09117%0.172CC..Hα-helixtrans-65.8-36.9169.3-75.1178.5-178.2-83.43.2112.9E66 Y69 P109 V110 K112 G113 I114 V115 F119 E120 H121E66-R117 VanDerWaalsContact CB-NH2 3.31Å; E66-R117 IonicContact OE2-NH1 2.87Å; E66-R117 IonicContact OE2-NH2 3.39Å; E66-R117 PolarHBondContact OE2-NH2 3.47Å; Y69-R117 HydrophobicContact CD1-CB 4.45Å; Y69-R117 HydrophobicContact CD2-CB 3.86Å; Y69-R117 HydrophobicContact CE1-CB 4.36Å; Y69-R117 HydrophobicContact CE2-CB 3.78Å; Y69-R117 HydrophobicContact CG-CB 4.21Å; Y69-R117 PolarHBondContact OH-O 3.35Å; P109-R117 PolarHBondContact O-NH2 3.05Å; V110-R117 PolarHBondContact O-NH2 2.91Å; K112-R117 HydrophobicContact CB-CG 4.44Å; K112-R117 HydrophobicContact CG-CG 4.2Å; K112-R117 WeakPolarHBondContact O-CD 3.41Å; K112-R117 PolarHBondContact O-NE 3.47Å; G113-R117 WeakPolarHBondContact O-CB 3.44Å; G113-R117 WeakPolarHBondContact O-CG 3.14Å; G113-R117 PolarHBondContact O-N 3.3Å; I114-R117 PolarHBondContact O-N 2.91Å; V115-R117 VanDerWaalsContact C-N 3.33Å; V115-R117 PolarHBondContact O-N 3.26Å; R117-F119 VanDerWaalsContact C-N 3.28Å; R117-F119 PolarHBondContact O-N 2.81Å; R117-E120 PolarHBondContact O-N 3.3Å; R117-H121 WeakPolarHBondContact O-CB 3.32Å; R117-H121 PolarHBondContact O-N 2.88Å
118T97.4Very high94.4Very high0 Ų027.2 Ų27.20%014%0.135CC..Hα-helixtrans-61-39.6173.5-71.70000110.9Y69 V77 I114 V115 H121 I122 L217 L236 L238Y69-T118 WeakPolarHBondContact OH-CA 3.45Å; V77-T118 HydrophobicContact CG2-CG2 4.06Å; I114-T118 WeakPolarHBondContact O-CB 3.41Å; I114-T118 PolarHBondContact O-N 3.49Å; I114-T118 PolarHBondContact O-OG1 3.34Å; I114-T118 VanDerWaalsContact O-OG1 3.05Å; V115-T118 WeakPolarHBondContact O-CB 3.33Å; V115-T118 PolarHBondContact O-N 2.85Å; T118-H121 PolarHBondContact O-N 2.85Å; T118-I122 HydrophobicContact CG2-CD1 3.58Å; T118-I122 HydrophobicContact CG2-CG1 4.26Å; T118-I122 WeakPolarHBondContact O-CB 3.3Å; T118-I122 VanDerWaalsContact O-CG1 3.27Å; T118-I122 WeakPolarHBondContact O-CG1 3.34Å; T118-I122 PolarHBondContact O-N 3.22Å; T118-L217 HydrophobicContact CG2-CD1 4.34Å; T118-L236 HydrophobicContact CG2-CD2 3.45Å; T118-L236 VanDerWaalsContact CG2-CD2 3.45Å; T118-L238 HydrophobicContact CG2-CD1 4.21Å
119F97Very high94.4Very high0 Ų022.3 Ų22.30%012%0.121CC..Hα-helixtrans-61.4-52.9175.9-54.9-22.1000111.2V115 P116 R117 H121 I122 F123 V183 C186 E187 L190 F215 L217V115-F119 HydrophobicContact CG1-CE1 3.91Å; V115-F119 HydrophobicContact CG1-CE2 3.87Å; V115-F119 HydrophobicContact CG1-CZ 3.35Å; V115-F119 WeakPolarHBondContact O-CD1 3.39Å; V115-F119 PolarHBondContact O-N 2.82Å; P116-F119 HydrophobicContact CB-CD2 4.4Å; P116-F119 WeakPolarHBondContact O-CB 3.4Å; P116-F119 PolarHBondContact O-N 3.37Å; R117-F119 VanDerWaalsContact C-N 3.28Å; R117-F119 PolarHBondContact O-N 2.81Å; F119-H121 VanDerWaalsContact C-N 3.28Å; F119-H121 PolarHBondContact O-N 2.83Å; F119-I122 PolarHBondContact O-N 2.89Å; F119-F123 VanDerWaalsContact O-CD2 3.26Å; F119-F123 WeakPolarHBondContact O-CD2 3.47Å; F119-F123 PolarHBondContact O-N 2.98Å; F119-V183 HydrophobicContact CB-CG1 4.08Å; F119-C186 HydrophobicContact CB-CB 4.3Å; F119-C186 HydrophobicContact CD1-CB 4.13Å; F119-C186 HydrophobicContact CD2-CB 3.52Å; F119-C186 HydrophobicContact CE1-CB 4.33Å; F119-C186 HydrophobicContact CE2-CB 3.74Å; F119-C186 HydrophobicContact CG-CB 3.73Å; F119-C186 HydrophobicContact CZ-CB 4.14Å; F119-E187 HydrophobicContact CD2-CG 4.17Å; F119-L190 HydrophobicContact CE2-CB 4.28Å; F119-L190 HydrophobicContact CE2-CD2 4.06Å; F119-F215 HydrophobicContact CE1-CD1 4.13Å; F119-F215 AromaticContact CE1-CE1 3.49Å; F119-F215 HydrophobicContact CE1-CE1 3.49Å; F119-F215 VanDerWaalsContact CE1-CE1 3.49Å; F119-F215 HydrophobicContact CE1-CZ 4.04Å; F119-F215 HydrophobicContact CZ-CD1 4.13Å; F119-F215 AromaticContact CZ-CE1 3.49Å; F119-F215 HydrophobicContact CZ-CE1 3.49Å; F119-F215 VanDerWaalsContact CZ-CE1 3.49Å; F119-F215 HydrophobicContact CZ-CE2 4.33Å; F119-F215 AromaticContact CZ-CZ 3.61Å; F119-F215 HydrophobicContact CZ-CZ 3.61Å; F119-L217 HydrophobicContact CD1-CD1 3.96Å; F119-L217 HydrophobicContact CE1-CD1 3.98Å; F119-L217 HydrophobicContact CE1-CD2 4.45Å; F119-L217 HydrophobicContact CE1-CG 4.45Å
120E95Very high94.1Very high79 Ų7923.9 Ų23.937%0.36912%0.12SC..Hα-helixtrans-54.2-46.6176.8-69.6175.1178.400111.8K112 P116 R117 E124 V183K112-E120 WeakPolarHBondContact CE-OE1 3.42Å; K112-E120 IonicContact NZ-OE1 2.84Å; K112-E120 PolarHBondContact NZ-OE1 3.36Å; P116-E120 PolarHBondContact O-N 2.83Å; R117-E120 PolarHBondContact O-N 3.3Å; E120-E124 WeakPolarHBondContact O-CB 3.46Å; E120-E124 PolarHBondContact O-N 3.43Å; E120-V183 HydrophobicContact CG-CG1 4.07Å
121H95.8Very high93.8Very high8 Ų827 Ų274%0.03713%0.134CC..Hα-helixtrans-63.5-45.3-179.3-177.3-166.7000112.7Y69 Y74 V77 E78 R117 T118 F119 A125Y69-H121 HydrophobicContact CE1-CB 4.46Å; Y69-H121 AromaticContact CZ-ND1 3.87Å; Y69-H121 WeakPolarHBondContact OH-CB 3.37Å; Y69-H121 PolarHBondContact OH-ND1 3.32Å; Y74-H121 AromaticContact CD1-CE1 3.91Å; Y74-H121 AromaticContact CD2-CE1 3.58Å; Y74-H121 AromaticContact CD2-ND1 3.93Å; Y74-H121 AromaticContact CD2-NE2 3.96Å; Y74-H121 AromaticContact CE1-CE1 3.89Å; Y74-H121 AromaticContact CE1-NE2 3.86Å; Y74-H121 AromaticContact CE2-CD2 3.96Å; Y74-H121 AromaticContact CE2-CE1 3.57Å; Y74-H121 AromaticContact CE2-NE2 3.45Å; Y74-H121 WeakPolarHBondContact CE2-NE2 3.41Å; Y74-H121 AromaticContact CG-CE1 3.74Å; Y74-H121 AromaticContact CZ-CE1 3.71Å; Y74-H121 AromaticContact CZ-NE2 3.37Å; Y74-H121 PolarHBondContact O-CE1 3.44Å; V77-H121 WeakPolarHBondContact CB-ND1 3.27Å; V77-H121 HydrophobicContact CG1-CB 4.42Å; V77-H121 VanDerWaalsContact CG1-ND1 3.3Å; V77-H121 WeakPolarHBondContact CG1-ND1 3.36Å; E78-H121 IonicContact OE1-CE1 3.53Å; E78-H121 IonicContact OE1-NE2 3.64Å; E78-H121 PolarHBondContact OE1-NE2 2.67Å; R117-H121 WeakPolarHBondContact O-CB 3.32Å; R117-H121 PolarHBondContact O-N 2.88Å; T118-H121 PolarHBondContact O-N 2.85Å; F119-H121 VanDerWaalsContact C-N 3.28Å; F119-H121 PolarHBondContact O-N 2.83Å; H121-A125 WeakPolarHBondContact O-CB 3.44Å; H121-A125 PolarHBondContact O-N 2.94Å
122I96.5Very high93.6Very high1 Ų127 Ų271%0.00514%0.136CC..Hα-helixtrans-63.9-48.1179.6-72.8172.1000110.5V77 L81 T118 F119 A125 I126 I136 L217 L219 L236V77-I122 HydrophobicContact CG1-CD1 4.26Å; V77-I122 HydrophobicContact CG1-CG1 3.57Å; L81-I122 HydrophobicContact CD2-CG2 4.36Å; T118-I122 HydrophobicContact CG2-CD1 3.58Å; T118-I122 HydrophobicContact CG2-CG1 4.26Å; T118-I122 WeakPolarHBondContact O-CB 3.3Å; T118-I122 VanDerWaalsContact O-CG1 3.27Å; T118-I122 WeakPolarHBondContact O-CG1 3.34Å; T118-I122 PolarHBondContact O-N 3.22Å; F119-I122 PolarHBondContact O-N 2.89Å; I122-A125 WeakPolarHBondContact O-CA 3.5Å; I122-A125 VanDerWaalsContact O-CB 3.25Å; I122-A125 WeakPolarHBondContact O-CB 3.49Å; I122-A125 PolarHBondContact O-N 3.17Å; I122-A125 VanDerWaalsContact O-N 3.12Å; I122-I126 HydrophobicContact CG2-CD1 3.56Å; I122-I126 HydrophobicContact CG2-CG1 4.42Å; I122-I126 VanDerWaalsContact O-CG1 3.26Å; I122-I126 WeakPolarHBondContact O-CG1 3.27Å; I122-I126 PolarHBondContact O-N 3.09Å; I122-I136 HydrophobicContact CG2-CD1 3.78Å; I122-L217 HydrophobicContact CD1-CD1 3.52Å; I122-L219 HydrophobicContact CG2-CD2 4.28Å; I122-L236 HydrophobicContact CD1-CD2 4.05Å
123F95.1Very high93.4Very high23 Ų2331.1 Ų31.110%0.10115%0.154CC..Hα-helixtrans-72-34.1-178.8-73.3-75.3000112.7F119 A125 I126 S127 I136 V180 H181 V183 I469F119-F123 VanDerWaalsContact O-CD2 3.26Å; F119-F123 WeakPolarHBondContact O-CD2 3.47Å; F119-F123 PolarHBondContact O-N 2.98Å; F123-A125 PolarHBondContact O-N 3.32Å; F123-I126 PolarHBondContact O-N 2.87Å; F123-S127 WeakPolarHBondContact O-CB 3.5Å; F123-S127 PolarHBondContact O-N 2.92Å; F123-S127 PolarHBondContact O-OG 2.9Å; F123-I136 HydrophobicContact CD1-CD1 4.32Å; F123-I136 HydrophobicContact CE1-CD1 3.7Å; F123-I136 HydrophobicContact CZ-CD1 3.82Å; F123-V180 HydrophobicContact CZ-CB 4.36Å; F123-V180 HydrophobicContact CZ-CG2 4.15Å; F123-H181 VanDerWaalsContact CE1-O 3.23Å; F123-H181 WeakPolarHBondContact CE1-O 3.07Å; F123-V183 HydrophobicContact CB-CG2 3.8Å; F123-V183 HydrophobicContact CD2-CB 4.43Å; F123-V183 HydrophobicContact CD2-CG2 3.7Å; F123-V183 HydrophobicContact CG-CG2 4.06Å; F123-I469 HydrophobicContact CD1-CD1 3.85Å; F123-I469 HydrophobicContact CE1-CD1 3.47Å; F123-I469 VanDerWaalsContact CE1-CD1 3.47Å
124E93.1Very high93.2Very high33 Ų3331.2 Ų31.215%0.15415%0.154CC..Hα-helixtrans-61-32.1168.9-178.1179.6175.800111E120 S127 T128 L479 K486E120-E124 WeakPolarHBondContact O-CB 3.46Å; E120-E124 PolarHBondContact O-N 3.43Å; E124-S127 PolarHBondContact O-OG 3.04Å; E124-T128 WeakPolarHBondContact O-CG2 3.36Å; E124-T128 PolarHBondContact O-OG1 3.37Å; E124-L479 HydrophobicContact CG-CD1 4.25Å; E124-K486 VanDerWaalsContact CD-NZ 3.29Å; E124-K486 IonicContact OE1-NZ 3.03Å; E124-K486 PolarHBondContact OE1-NZ 3.45Å; E124-K486 IonicContact OE2-NZ 3.45Å; E124-K486 PolarHBondContact OE2-NZ 3.15Å
125A92.7Very high93Very high0 Ų032.4 Ų32.40%016%0.16CC..Hα-helixtrans-72.3-47.9176.100000113.9L81 H121 I122 F123 S127 T128 T129L81-A125 HydrophobicContact CD1-CB 3.29Å; L81-A125 HydrophobicContact CD2-CB 3.99Å; L81-A125 HydrophobicContact CG-CB 4.26Å; H121-A125 WeakPolarHBondContact O-CB 3.44Å; H121-A125 PolarHBondContact O-N 2.94Å; I122-A125 WeakPolarHBondContact O-CA 3.5Å; I122-A125 VanDerWaalsContact O-CB 3.25Å; I122-A125 WeakPolarHBondContact O-CB 3.49Å; I122-A125 PolarHBondContact O-N 3.17Å; I122-A125 VanDerWaalsContact O-N 3.12Å; F123-A125 PolarHBondContact O-N 3.32Å; A125-S127 VanDerWaalsContact C-N 3.28Å; A125-S127 PolarHBondContact O-N 3.16Å; A125-T128 PolarHBondContact O-N 3.18Å; A125-T128 PolarHBondContact O-OG1 2.93Å; A125-T128 VanDerWaalsContact O-OG1 3.13Å; A125-T129 WeakPolarHBondContact O-CB 3.49Å; A125-T129 PolarHBondContact O-N 2.99Å; A125-T129 VanDerWaalsContact O-N 3.07Å; A125-T129 PolarHBondContact O-OG1 2.91Å
126I92.3Very high93Very high4 Ų432.2 Ų32.22%0.02116%0.159CC..Hα-helixtrans-66.9-37.1-176.1-70.6171.4000110.1L81 I122 F123 T128 F134 I136 I469 G471L81-I126 HydrophobicContact CD2-CG1 4.17Å; I122-I126 HydrophobicContact CG2-CD1 3.56Å; I122-I126 HydrophobicContact CG2-CG1 4.42Å; I122-I126 VanDerWaalsContact O-CG1 3.26Å; I122-I126 WeakPolarHBondContact O-CG1 3.27Å; I122-I126 PolarHBondContact O-N 3.09Å; F123-I126 PolarHBondContact O-N 2.87Å; I126-T128 PolarHBondContact O-N 3.38Å; I126-F134 HydrophobicContact CB-CD2 4.07Å; I126-F134 HydrophobicContact CB-CE2 4.36Å; I126-F134 HydrophobicContact CB-CG 4.34Å; I126-F134 HydrophobicContact CD1-CB 3.85Å; I126-F134 HydrophobicContact CD1-CD1 3.84Å; I126-F134 HydrophobicContact CD1-CD2 4.36Å; I126-F134 HydrophobicContact CD1-CE1 4.46Å; I126-F134 HydrophobicContact CD1-CG 3.77Å; I126-F134 HydrophobicContact CG1-CB 4.16Å; I126-F134 HydrophobicContact CG1-CD1 3.74Å; I126-F134 HydrophobicContact CG1-CD2 3.72Å; I126-F134 HydrophobicContact CG1-CE1 3.97Å; I126-F134 HydrophobicContact CG1-CE2 3.95Å; I126-F134 HydrophobicContact CG1-CG 3.61Å; I126-F134 HydrophobicContact CG1-CZ 4.08Å; I126-F134 HydrophobicContact CG2-CB 4.01Å; I126-F134 HydrophobicContact CG2-CD2 3.6Å; I126-F134 HydrophobicContact CG2-CE2 4.28Å; I126-F134 HydrophobicContact CG2-CG 3.96Å; I126-I136 HydrophobicContact CD1-CD1 3.27Å; I126-I136 HydrophobicContact CD1-CG1 4.03Å; I126-I469 HydrophobicContact CG2-CB 4.47Å; I126-I469 HydrophobicContact CG2-CD1 4.01Å; I126-I469 HydrophobicContact CG2-CG1 3.99Å; I126-G471 PolarHBondContact O-N 2.78Å
127S91.2Very high92.9Very high10 Ų1032.9 Ų32.97%0.0716%0.164CC..Hα-helixtrans-68.6-20.5178.373.70000113.9F123 E124 A125 G471 E472 Q473F123-S127 WeakPolarHBondContact O-CB 3.5Å; F123-S127 PolarHBondContact O-N 2.92Å; F123-S127 PolarHBondContact O-OG 2.9Å; E124-S127 PolarHBondContact O-OG 3.04Å; A125-S127 VanDerWaalsContact C-N 3.28Å; A125-S127 PolarHBondContact O-N 3.16Å; S127-G471 CarbonylContact O-C 3.56Å; S127-E472 PolarHBondContact O-N 2.95Å; S127-Q473 CarbonylContact O-C 3.55Å; S127-Q473 WeakPolarHBondContact O-CA 3.2Å; S127-Q473 PolarHBondContact O-N 2.85Å; S127-Q473 PolarHBondContact OG-OE1 2.89Å
128T89.9Confident93Very high13 Ų1331.8 Ų31.88%0.0816%0.16CC..Hα-helixtrans-113.40.5-174.554.50000113.9E124 A125 I126 L474 L479 V480 R483E124-T128 WeakPolarHBondContact O-CG2 3.36Å; E124-T128 PolarHBondContact O-OG1 3.37Å; A125-T128 PolarHBondContact O-N 3.18Å; A125-T128 PolarHBondContact O-OG1 2.93Å; A125-T128 VanDerWaalsContact O-OG1 3.13Å; I126-T128 PolarHBondContact O-N 3.38Å; T128-L474 VanDerWaalsContact O-CD2 3.29Å; T128-L474 WeakPolarHBondContact O-CD2 3.23Å; T128-L479 HydrophobicContact CG2-CD2 3.83Å; T128-L479 HydrophobicContact CG2-CG 3.96Å; T128-V480 HydrophobicContact CG2-CG2 4.11Å; T128-R483 WeakPolarHBondContact OG1-CD 3.43Å; T128-R483 PolarHBondContact OG1-NE 2.98Å
129T89.1Confident93Very high43 Ų4331.8 Ų31.826%0.26416%0.16SC..  trans-90.5131.3178.3-59.80000110A125 V132 F134A125-T129 WeakPolarHBondContact O-CB 3.49Å; A125-T129 PolarHBondContact O-N 2.99Å; A125-T129 VanDerWaalsContact O-N 3.07Å; A125-T129 PolarHBondContact O-OG1 2.91Å; T129-V132 HydrophobicContact CG2-CB 3.93Å; T129-V132 HydrophobicContact CG2-CG2 3.96Å; T129-F134 HydrophobicContact CG2-CE2 4.35Å; T129-F134 HydrophobicContact CG2-CZ 4.43Å
130E85.7Confident93Very high128 Ų12832 Ų3260%0.59816%0.161SC*.SBendtrans-88.4148.1178.5-63.9-179-177.200111.4V132 L474E130-V132 PolarHBondContact O-N 2.91Å; E130-L474 HydrophobicContact CB-CD2 4.43Å; E130-L474 HydrophobicContact CG-CD1 3.82Å; E130-L474 HydrophobicContact CG-CD2 3.31Å; E130-L474 HydrophobicContact CG-CG 4.18Å
131N85.4Confident93Very high125 Ų12528.5 Ų28.567%0.66814%0.144SC*.SBendtrans5812.9172.9-53.7-43.6000116.4V224N131-V224 PolarHBondContact O-N 2.88Å
132V90.3Very high92.9Very high21 Ų2128.2 Ų28.213%0.12714%0.143CC..EExtended strand (participates in β ladder)trans-125.3126.5175-171.70000109T129 E130 F134 M221 F222 E223T129-V132 HydrophobicContact CG2-CB 3.93Å; T129-V132 HydrophobicContact CG2-CG2 3.96Å; E130-V132 PolarHBondContact O-N 2.91Å; V132-F134 HydrophobicContact CB-CE2 3.77Å; V132-F134 HydrophobicContact CB-CZ 4.12Å; V132-F134 HydrophobicContact CG1-CD2 4.07Å; V132-F134 HydrophobicContact CG1-CE1 4.23Å; V132-F134 HydrophobicContact CG1-CE2 3.48Å; V132-F134 VanDerWaalsContact CG1-CE2 3.48Å; V132-F134 HydrophobicContact CG1-CZ 3.56Å; V132-M221 HydrophobicContact CG1-CB 4.13Å; V132-F222 WeakPolarHBondContact CA-O 2.85Å; V132-E223 HydrophobicContact CG2-CB 4.15Å; V132-E223 HydrophobicContact CG2-CG 4.05Å
133K90.4Very high92.8Very high126 Ų12628.2 Ų28.255%0.54814%0.143SC..EExtended strand (participates in β ladder)trans-102.9146.4171.9-78.7-176.5179.5-170.90109.3M221 F222 I468K133-M221 CarbonylContact O-C 3.56Å; K133-M221 WeakPolarHBondContact O-CA 3.21Å; K133-F222 HydrophobicContact CB-CB 4.19Å; K133-F222 PolarHBondContact N-O 3.35Å; K133-F222 PolarHBondContact O-N 3.47Å; K133-I468 HydrophobicContact CB-CG2 3.49Å; K133-I468 VanDerWaalsContact CB-CG2 3.49Å; K133-I468 HydrophobicContact CD-CG2 3.72Å; K133-I468 HydrophobicContact CG-CG2 3.91Å
134F93.5Very high92.5Very high3 Ų328.2 Ų28.21%0.01314%0.143CC..EExtended strand (participates in β ladder)trans-126.6138.5-174.2-64.1-103.3000110.3L81 I126 T129 V132 E220 M221 I469L81-F134 HydrophobicContact CD2-CE1 4.15Å; I126-F134 HydrophobicContact CB-CD2 4.07Å; I126-F134 HydrophobicContact CB-CE2 4.36Å; I126-F134 HydrophobicContact CB-CG 4.34Å; I126-F134 HydrophobicContact CD1-CB 3.85Å; I126-F134 HydrophobicContact CD1-CD1 3.84Å; I126-F134 HydrophobicContact CD1-CD2 4.36Å; I126-F134 HydrophobicContact CD1-CE1 4.46Å; I126-F134 HydrophobicContact CD1-CG 3.77Å; I126-F134 HydrophobicContact CG1-CB 4.16Å; I126-F134 HydrophobicContact CG1-CD1 3.74Å; I126-F134 HydrophobicContact CG1-CD2 3.72Å; I126-F134 HydrophobicContact CG1-CE1 3.97Å; I126-F134 HydrophobicContact CG1-CE2 3.95Å; I126-F134 HydrophobicContact CG1-CG 3.61Å; I126-F134 HydrophobicContact CG1-CZ 4.08Å; I126-F134 HydrophobicContact CG2-CB 4.01Å; I126-F134 HydrophobicContact CG2-CD2 3.6Å; I126-F134 HydrophobicContact CG2-CE2 4.28Å; I126-F134 HydrophobicContact CG2-CG 3.96Å; T129-F134 HydrophobicContact CG2-CE2 4.35Å; T129-F134 HydrophobicContact CG2-CZ 4.43Å; V132-F134 HydrophobicContact CB-CE2 3.77Å; V132-F134 HydrophobicContact CB-CZ 4.12Å; V132-F134 HydrophobicContact CG1-CD2 4.07Å; V132-F134 HydrophobicContact CG1-CE1 4.23Å; V132-F134 HydrophobicContact CG1-CE2 3.48Å; V132-F134 VanDerWaalsContact CG1-CE2 3.48Å; V132-F134 HydrophobicContact CG1-CZ 3.56Å; F134-E220 CarbonylContact C-O 3.36Å; F134-E220 VanDerWaalsContact CA-O 3.31Å; F134-E220 WeakPolarHBondContact CA-O 3.41Å; F134-M221 HydrophobicContact CD1-CG 3.55Å; F134-M221 HydrophobicContact CD1-SD 4.46Å; F134-M221 HydrophobicContact CE1-CB 4.47Å; F134-M221 HydrophobicContact CE1-CG 3.47Å; F134-M221 VanDerWaalsContact CE1-CG 3.47Å; F134-M221 HydrophobicContact CE1-SD 3.86Å; F134-M221 HydrophobicContact CZ-CG 4.41Å; F134-I469 HydrophobicContact CB-CG1 4.36Å; F134-I469 PolarHBondContact N-O 2.82Å; F134-I469 WeakPolarHBondContact O-CG1 3.45Å; F134-I469 PolarHBondContact O-N 3.42Å
135L93.4Very high92.1Very high24 Ų2428.4 Ų28.413%0.12615%0.145CC..EExtended strand (participates in β ladder)trans-115.2121.6164.2175.367000107.5E220 F222 Q467L135-E220 HydrophobicContact CB-CB 4.3Å; L135-E220 PolarHBondContact N-O 3.13Å; L135-E220 PolarHBondContact O-N 3.42Å; L135-F222 HydrophobicContact CB-CE2 3.96Å; L135-Q467 HydrophobicContact CD1-CB 3.82Å
136I95.8Very high92Very high2 Ų230.2 Ų30.21%0.0115%0.153CC..EExtended strand (participates in β ladder)trans-114.9126.7-179.5-47.7177.6000109.4I122 F123 I126 P179 V180 L217 H218 L219 I469I122-I136 HydrophobicContact CG2-CD1 3.78Å; F123-I136 HydrophobicContact CD1-CD1 4.32Å; F123-I136 HydrophobicContact CE1-CD1 3.7Å; F123-I136 HydrophobicContact CZ-CD1 3.82Å; I126-I136 HydrophobicContact CD1-CD1 3.27Å; I126-I136 HydrophobicContact CD1-CG1 4.03Å; I136-P179 WeakPolarHBondContact O-CA 3.45Å; I136-V180 HydrophobicContact CB-CG2 3.8Å; I136-V180 HydrophobicContact CG2-CG2 3.56Å; I136-V180 WeakPolarHBondContact O-CG2 3.08Å; I136-V180 PolarHBondContact O-N 3.37Å; I136-L217 HydrophobicContact CG2-CD2 4.1Å; I136-H218 CarbonylContact C-O 3.59Å; I136-H218 WeakPolarHBondContact CA-O 3.26Å; I136-L219 HydrophobicContact CG1-CG 4.49Å; I136-I469 HydrophobicContact CD1-CD1 4.08Å; I136-I469 HydrophobicContact CG1-CD1 4.44Å
137C95.8Very high91.9Very high24 Ų2432.3 Ų32.316%0.16216%0.164CC..EExtended strand (participates in β ladder)trans-119.3129.7172.5-70.30000110.2M177 H178 H218C137-M177 HydrophobicContact CB-CE 3.59Å; C137-H178 CarbonylContact C-O 3.16Å; C137-H178 WeakPolarHBondContact CA-O 3.39Å; C137-H218 HydrophobicContact CB-CB 4.25Å; C137-H218 PolarHBondContact N-O 3.33Å; C137-H218 PolarHBondContact O-N 2.94Å
138A97.5Very high92Very high0 Ų032 Ų320%016%0.162CC..EExtended strand (participates in β ladder)trans-99.7141174.900000111.2H178 V180 L189 F215 T216 L217A138-H178 PolarHBondContact N-O 3.02Å; A138-H178 PolarHBondContact O-N 2.91Å; A138-V180 HydrophobicContact CB-CG1 4.16Å; A138-V180 HydrophobicContact CB-CG2 4.45Å; A138-L189 HydrophobicContact CB-CD1 3.92Å; A138-F215 HydrophobicContact CB-CE1 4.31Å; A138-F215 HydrophobicContact CB-CZ 3.93Å; A138-T216 WeakPolarHBondContact CA-O 3.4Å; A138-L217 HydrophobicContact CB-CD2 3.95Å
139S96.9Very high92.2Very high1 Ų132.8 Ų32.81%0.00716%0.163CC..EExtended strand (participates in β ladder)trans-132148.6165.462.80000109.9S176 T216S139-S176 WeakPolarHBondContact CB-O 3.31Å; S139-T216 PolarHBondContact N-O 3.44Å; S139-T216 PolarHBondContact O-N 3.39Å
140Y97.4Very high92.5Very high3 Ų331.1 Ų31.11%0.01215%0.153CC..EExtended strand (participates in β ladder)trans-138.8118.7176.7-167.8-166.9000109.7L151 L190 M194 S213 I214 F215Y140-L151 HydrophobicContact CD1-CB 4.17Å; Y140-L151 HydrophobicContact CD1-CD1 3.83Å; Y140-L151 HydrophobicContact CD2-CD1 3.83Å; Y140-L151 HydrophobicContact CE1-CD1 3.71Å; Y140-L151 HydrophobicContact CE2-CD1 3.76Å; Y140-L151 HydrophobicContact CG-CB 4.21Å; Y140-L151 HydrophobicContact CG-CD1 3.86Å; Y140-L151 WeakPolarHBondContact O-CB 3.46Å; Y140-L151 PolarHBondContact O-N 3.49Å; Y140-L190 HydrophobicContact CE1-CD1 4.22Å; Y140-M194 HydrophobicContact CE1-CG 4.46Å; Y140-S213 PolarHBondContact OH-OG 3.06Å; Y140-I214 WeakPolarHBondContact CD2-O 3.32Å; Y140-F215 AromaticContact CD1-CD2 3.86Å; Y140-F215 HydrophobicContact CD1-CD2 3.86Å; Y140-F215 HydrophobicContact CD1-CE2 4.41Å; Y140-F215 HydrophobicContact CD2-CB 3.86Å; Y140-F215 AromaticContact CD2-CD2 3.89Å; Y140-F215 HydrophobicContact CD2-CD2 3.89Å; Y140-F215 HydrophobicContact CD2-CG 4.36Å; Y140-F215 HydrophobicContact CE1-CD2 4.47Å; Y140-F215 HydrophobicContact CE2-CB 4.12Å; Y140-F215 HydrophobicContact CE2-CD2 4.45Å; Y140-F215 HydrophobicContact CG-CB 4.41Å; Y140-F215 AromaticContact CG-CD2 3.57Å; Y140-F215 HydrophobicContact CG-CD2 3.57Å; Y140-F215 HydrophobicContact CG-CE2 4.33Å; Y140-F215 HydrophobicContact CG-CG 4.44Å
141L95.7Very high92.9Very high6 Ų625.1 Ų25.13%0.03113%0.125CC..EExtended strand (participates in β ladder)trans-125.3157.9-178.669.683.1000111.6I143 V148 R149 V172 L175 S213 I214 L295L141-I143 HydrophobicContact CD1-CD1 4.45Å; L141-I143 HydrophobicContact CD1-CG1 3.86Å; L141-V148 HydrophobicContact CD1-CG1 4.38Å; L141-R149 CarbonylContact C-O 3.52Å; L141-R149 VanDerWaalsContact CA-O 3.25Å; L141-R149 WeakPolarHBondContact CA-O 3.29Å; L141-R149 WeakPolarHBondContact CB-O 3.29Å; L141-V172 HydrophobicContact CD2-CG2 4.12Å; L141-L175 HydrophobicContact CB-CD1 4Å; L141-L175 HydrophobicContact CD2-CD1 4.31Å; L141-L175 HydrophobicContact CD2-CD2 3.99Å; L141-S213 WeakPolarHBondContact O-CA 3.49Å; L141-I214 HydrophobicContact CD1-CB 3.84Å; L141-I214 HydrophobicContact CD1-CD1 4.08Å; L141-I214 HydrophobicContact CD1-CG1 4.09Å; L141-I214 HydrophobicContact CG-CB 4Å; L141-I214 PolarHBondContact N-O 3.36Å; L141-I214 PolarHBondContact O-N 2.96Å; L141-L295 HydrophobicContact CD1-CD1 4.19Å; L141-L295 HydrophobicContact CD2-CD1 4.32Å
142E94.1Very high93.4Very high2 Ų219.2 Ų19.21%0.0099%0.093CC..EExtended strand (participates in β ladder)trans-121.2140.7174.1-171.6-175-151.800109.6R149 L151 R197 S211 H212E142-R149 VanDerWaalsContact CD-NH2 3.31Å; E142-R149 PolarHBondContact N-O 3.37Å; E142-R149 PolarHBondContact O-N 2.85Å; E142-R149 IonicContact OE1-NH2 3.79Å; E142-R149 IonicContact OE2-CZ 2.77Å; E142-R149 IonicContact OE2-NE 3.4Å; E142-R149 PolarHBondContact OE2-NE 3.17Å; E142-R149 IonicContact OE2-NH2 3.5Å; E142-R149 PolarHBondContact OE2-NH2 2.89Å; E142-L151 HydrophobicContact CB-CD1 4.02Å; E142-L151 HydrophobicContact CB-CD2 3.94Å; E142-L151 HydrophobicContact CB-CG 3.96Å; E142-R197 WeakPolarHBondContact OE1-CG 3.46Å; E142-R197 IonicContact OE1-NE 3.76Å; E142-S211 WeakPolarHBondContact OE1-CB 3.23Å; E142-S211 PolarHBondContact OE1-OG 3Å; E142-H212 CarbonylContact C-O 3.58Å; E142-H212 VanDerWaalsContact CA-O 3.31Å; E142-H212 WeakPolarHBondContact CA-O 3.47Å
143I93Very high93.4Very high1 Ų118.9 Ų18.91%0.0059%0.094CC..EExtended strand (participates in β ladder)trans-115.1118.5168.2-47174.4000107.8L141 D147 V148 S211 H212 I214 L292 L295L141-I143 HydrophobicContact CD1-CD1 4.45Å; L141-I143 HydrophobicContact CD1-CG1 3.86Å; I143-D147 WeakPolarHBondContact CA-O 3.34Å; I143-V148 HydrophobicContact CG1-CG2 4.47Å; I143-S211 WeakPolarHBondContact O-CA 3.49Å; I143-H212 HydrophobicContact CB-CB 4.23Å; I143-H212 PolarHBondContact N-O 3.32Å; I143-H212 PolarHBondContact O-N 2.92Å; I143-I214 HydrophobicContact CD1-CD1 4.12Å; I143-L292 HydrophobicContact CD1-CB 4.08Å; I143-L292 HydrophobicContact CD1-CD1 3.94Å; I143-L295 HydrophobicContact CD1-CD1 3.76Å; I143-L295 HydrophobicContact CG1-CD1 4.46Å
144Y89.3Confident93.2Very high23 Ų2325.5 Ų25.59%0.0912%0.115CC..EExtended strand (participates in β ladder)trans-137.3124.3177.9174-108.6000108.9E146 D147 T206 R210 E259Y144-E146 PolarHBondContact O-N 3.39Å; Y144-D147 PolarHBondContact N-O 3.27Å; Y144-D147 WeakPolarHBondContact O-CB 3.38Å; Y144-D147 PolarHBondContact O-N 2.92Å; Y144-T206 HydrophobicContact CD1-CG2 4.13Å; Y144-T206 HydrophobicContact CD2-CG2 3.95Å; Y144-T206 HydrophobicContact CE1-CG2 3.73Å; Y144-T206 HydrophobicContact CE2-CG2 3.58Å; Y144-T206 HydrophobicContact CG-CG2 4.2Å; Y144-T206 VanDerWaalsContact CZ-CG2 3.43Å; Y144-T206 PolarHBondContact OH-OG1 3.26Å; Y144-R210 HydrophobicContact CD2-CB 4.48Å; Y144-R210 HydrophobicContact CE2-CB 4.13Å; Y144-E259 WeakPolarHBondContact CE2-OE1 3.47Å; Y144-E259 PolarHBondContact OH-OE1 3.37Å
145I85.1Confident93Very high38 Ų3829.3 Ų29.320%0.19514%0.136CC..THydrogen-bonded Turntrans5343.6-178.1-49.2-179.9000110.8D147 E259 K262I145-D147 PolarHBondContact O-N 3.35Å; I145-E259 HydrophobicContact CD1-CB 3.9Å; I145-E259 HydrophobicContact CD1-CG 3.6Å; I145-E259 HydrophobicContact CG1-CG 4Å; I145-K262 HydrophobicContact CG2-CB 3.73Å; I145-K262 HydrophobicContact CG2-CD 3.24Å; I145-K262 HydrophobicContact CG2-CG 4.14Å
146E89.2Confident92.6Very high38 Ų3830.4 Ų30.418%0.17814%0.143CC..THydrogen-bonded Turntrans62.32-176.7-62.3-65.1119.600116.4Y144 L265 S266 S290 K291Y144-E146 PolarHBondContact O-N 3.39Å; E146-L265 HydrophobicContact CG-CD2 4.33Å; E146-S266 WeakPolarHBondContact OE1-CB 3.41Å; E146-S290 WeakPolarHBondContact OE2-CA 3.39Å; E146-K291 HydrophobicContact CB-CG 4.48Å; E146-K291 WeakPolarHBondContact O-CG 3.39Å; E146-K291 WeakPolarHBondContact OE2-CG 3.47Å; E146-K291 PolarHBondContact OE2-N 3.47Å
147D91.2Very high92Very high48 Ų4837.6 Ų37.626%0.25718%0.175SC..EExtended strand (participates in β ladder)trans-86.4128.5170.4-70.3-38.4000109.7I143 Y144 I145 K159I143-D147 WeakPolarHBondContact CA-O 3.34Å; Y144-D147 PolarHBondContact N-O 3.27Å; Y144-D147 WeakPolarHBondContact O-CB 3.38Å; Y144-D147 PolarHBondContact O-N 2.92Å; I145-D147 PolarHBondContact O-N 3.35Å; D147-K159 WeakPolarHBondContact OD1-CD 3.43Å; D147-K159 IonicContact OD1-NZ 2.86Å; D147-K159 PolarHBondContact OD1-NZ 3.42Å; D147-K159 WeakPolarHBondContact OD2-CE 3.39Å; D147-K159 IonicContact OD2-NZ 3.93Å; D147-K159 PolarHBondContact OD2-NZ 3.35Å
148V94Very high91.7Very high3 Ų341.6 Ų41.62%0.01819%0.191CC..EExtended strand (participates in β ladder)trans-93127.4174.5-176.20000108.9L141 I143 L160 I162 V172 K291L141-V148 HydrophobicContact CD1-CG1 4.38Å; I143-V148 HydrophobicContact CG1-CG2 4.47Å; V148-L160 HydrophobicContact CB-CB 4.41Å; V148-L160 HydrophobicContact CG1-CB 4.31Å; V148-L160 PolarHBondContact O-N 3.13Å; V148-I162 HydrophobicContact CG2-CD1 4.19Å; V148-I162 HydrophobicContact CG2-CG1 4.24Å; V148-V172 HydrophobicContact CG1-CG1 3.99Å; V148-V172 HydrophobicContact CG1-CG2 4.36Å; V148-K291 HydrophobicContact CG2-CB 4.22Å; V148-K291 HydrophobicContact CG2-CG 4.41Å
149R93Very high91.5Very high30 Ų3047.9 Ų47.911%0.11322%0.218CC..EExtended strand (participates in β ladder)trans-127.7146.3178.5-64.7-174.7-65.3-95.19.4111L141 E142 T156L141-R149 CarbonylContact C-O 3.52Å; L141-R149 VanDerWaalsContact CA-O 3.25Å; L141-R149 WeakPolarHBondContact CA-O 3.29Å; L141-R149 WeakPolarHBondContact CB-O 3.29Å; E142-R149 VanDerWaalsContact CD-NH2 3.31Å; E142-R149 PolarHBondContact N-O 3.37Å; E142-R149 PolarHBondContact O-N 2.85Å; E142-R149 IonicContact OE1-NH2 3.79Å; E142-R149 IonicContact OE2-CZ 2.77Å; E142-R149 IonicContact OE2-NE 3.4Å; E142-R149 PolarHBondContact OE2-NE 3.17Å; E142-R149 IonicContact OE2-NH2 3.5Å; E142-R149 PolarHBondContact OE2-NH2 2.89Å; R149-T156 WeakPolarHBondContact CD-O 3.48Å
150D95.5Very high91.4Very high7 Ų748.7 Ų48.74%0.03722%0.223CC..EExtended strand (participates in β ladder)trans-91.1119.4173.7-178.5-4.3000110.5L152 G153 L160 L175 S176D150-L152 WeakPolarHBondContact OD1-CA 3.33Å; D150-L152 PolarHBondContact OD1-N 2.97Å; D150-G153 PolarHBondContact OD1-N 2.98Å; D150-G153 WeakPolarHBondContact OD2-CA 3.39Å; D150-G153 PolarHBondContact OD2-N 2.88Å; D150-L160 HydrophobicContact CB-CD1 3.76Å; D150-L175 HydrophobicContact CB-CD1 4.06Å; D150-S176 VanDerWaalsContact CG-OG 3.3Å; D150-S176 PolarHBondContact OD1-OG 3.27Å; D150-S176 WeakPolarHBondContact OD2-CA 3.49Å; D150-S176 WeakPolarHBondContact OD2-CB 3.25Å; D150-S176 PolarHBondContact OD2-N 2.91Å; D150-S176 PolarHBondContact OD2-OG 2.86Å
151L94.7Very high91.2Very high3 Ų355 Ų552%0.01625%0.252CS..SBendtrans-81.4-14.9-179.8-65.3175.9000112.9Y140 E142 N196 R197Y140-L151 HydrophobicContact CD1-CB 4.17Å; Y140-L151 HydrophobicContact CD1-CD1 3.83Å; Y140-L151 HydrophobicContact CD2-CD1 3.83Å; Y140-L151 HydrophobicContact CE1-CD1 3.71Å; Y140-L151 HydrophobicContact CE2-CD1 3.76Å; Y140-L151 HydrophobicContact CG-CB 4.21Å; Y140-L151 HydrophobicContact CG-CD1 3.86Å; Y140-L151 WeakPolarHBondContact O-CB 3.46Å; Y140-L151 PolarHBondContact O-N 3.49Å; E142-L151 HydrophobicContact CB-CD1 4.02Å; E142-L151 HydrophobicContact CB-CD2 3.94Å; E142-L151 HydrophobicContact CB-CG 3.96Å; L151-N196 HydrophobicContact CD2-CB 4.38Å; L151-N196 PolarHBondContact O-ND2 3.47Å; L151-R197 HydrophobicContact CD1-CB 4.25Å; L151-R197 HydrophobicContact CD2-CB 4Å
152L95.4Very high91.1Very high1 Ų155.4 Ų55.41%0.00525%0.254CS..SBendtrans-106.4-13.1178.7-53.8179.8000113.1D150 H178 L189 K192D150-L152 WeakPolarHBondContact OD1-CA 3.33Å; D150-L152 PolarHBondContact OD1-N 2.97Å; L152-H178 WeakPolarHBondContact CB-NE2 3.29Å; L152-L189 HydrophobicContact CD1-CB 4.37Å; L152-L189 HydrophobicContact CD1-CD2 4.36Å; L152-L189 HydrophobicContact CD2-CB 4.25Å; L152-L189 HydrophobicContact CD2-CD2 4.35Å; L152-L189 VanDerWaalsContact CD2-O 3.22Å; L152-L189 WeakPolarHBondContact CD2-O 3.33Å; L152-K192 PolarHBondContact O-NZ 3.04Å
153G89.8Confident91.1Very high13 Ų1359.9 Ų59.913%0.13427%0.274CS..SBendtrans-60.6169.3179.800000114D150 S176D150-G153 PolarHBondContact OD1-N 2.98Å; D150-G153 WeakPolarHBondContact OD2-CA 3.39Å; D150-G153 PolarHBondContact OD2-N 2.88Å; G153-S176 PolarHBondContact N-OG 2.97Å
154R87.6Confident91Very high266 Ų26664.2 Ų64.2100%1.00429%0.294SS*.SBendtrans-71.5-41.5176.9-62.7-179.7-176.6-178.90.4111.4
155D88.1Confident90.8Very high83 Ų8367 Ų6744%0.44431%0.307SS..  trans-111.9102.5174.7-177.36.7000109.6K157 Q158D155-K157 PolarHBondContact O-N 2.82Å; D155-K157 WeakPolarHBondContact OD1-CB 3.31Å; D155-K157 PolarHBondContact OD1-N 3.41Å; D155-Q158 HydrophobicContact CB-CB 4.2Å; D155-Q158 PolarHBondContact O-N 3.05Å
156T85.9Confident90.5Very high46 Ų4674.7 Ų74.728%0.28234%0.343SS..THydrogen-bonded Turntrans-74.4-9.3178.954.70000113R149 N196R149-T156 WeakPolarHBondContact CD-O 3.48Å; T156-N196 HydrophobicContact CG2-CB 4.07Å
157K83.8Confident90Very high154 Ų15480.7 Ų80.767%0.6737%0.37SS*.THydrogen-bonded Turntrans-93.2-13.5177.7-61-178.8179.7179.50112.5D155 K159D155-K157 PolarHBondContact O-N 2.82Å; D155-K157 WeakPolarHBondContact OD1-CB 3.31Å; D155-K157 PolarHBondContact OD1-N 3.41Å; K157-K159 PolarHBondContact O-N 2.97Å
158Q89.5Confident89.3Confident108 Ų10887.2 Ų87.251%0.50539%0.391SS..PPolyproline II helixtrans-62.6128.9178.5-171.9178.426.500110.6D155 L160D155-Q158 HydrophobicContact CB-CB 4.2Å; D155-Q158 PolarHBondContact O-N 3.05Å; Q158-L160 HydrophobicContact CG-CD2 4.21Å
159K91.9Very high88.8Confident132 Ų13288.6 Ų88.657%0.57441%0.406SS*.PPolyproline II helixtrans-82.7124.4172.9-60.4-175.6178.2-150.60109.4D147 K157D147-K159 WeakPolarHBondContact OD1-CD 3.43Å; D147-K159 IonicContact OD1-NZ 2.86Å; D147-K159 PolarHBondContact OD1-NZ 3.42Å; D147-K159 WeakPolarHBondContact OD2-CE 3.39Å; D147-K159 IonicContact OD2-NZ 3.93Å; D147-K159 PolarHBondContact OD2-NZ 3.35Å; K157-K159 PolarHBondContact O-N 2.97Å
160L94.4Very high88.7Confident18 Ų1888.7 Ų88.79%0.09441%0.41CS..BIsolated β-bridgetrans-99.6150.5178.7-58.5-175.7000111.6V148 D150 Q158 V172 L175V148-L160 HydrophobicContact CB-CB 4.41Å; V148-L160 HydrophobicContact CG1-CB 4.31Å; V148-L160 PolarHBondContact O-N 3.13Å; D150-L160 HydrophobicContact CB-CD1 3.76Å; Q158-L160 HydrophobicContact CG-CD2 4.21Å; L160-V172 HydrophobicContact CB-CG1 3.59Å; L160-V172 HydrophobicContact CD1-CG1 3.8Å; L160-V172 HydrophobicContact CG-CG1 4.36Å; L160-L175 HydrophobicContact CD1-CB 4.33Å; L160-L175 HydrophobicContact CD1-CD1 4.3Å
161E93.9Very high88.5Confident136 Ų13692.5 Ų92.564%0.63643%0.425SS*.EExtended strand (participates in β ladder)trans-105.9143179.6-67.4-171.216200112.1A173E161-A173 PolarHBondContact O-N 2.78Å
162I94.4Very high88.5Confident13 Ų1393.1 Ų93.17%0.06743%0.428CS..EExtended strand (participates in β ladder)trans-89.6122.2174.3-56.4-176.9000109.6V148 V170 V172 K291 R294 L295V148-I162 HydrophobicContact CG2-CD1 4.19Å; V148-I162 HydrophobicContact CG2-CG1 4.24Å; I162-V170 HydrophobicContact CG2-CG1 3.31Å; I162-V172 HydrophobicContact CG1-CG2 4.39Å; I162-K291 HydrophobicContact CD1-CB 3.7Å; I162-K291 HydrophobicContact CD1-CD 3.8Å; I162-K291 HydrophobicContact CD1-CG 4.19Å; I162-K291 WeakPolarHBondContact CD1-O 3.48Å; I162-K291 HydrophobicContact CG1-CD 4.35Å; I162-R294 HydrophobicContact CD1-CB 4.37Å; I162-L295 HydrophobicContact CD1-CD1 4.18Å; I162-L295 HydrophobicContact CD1-CD2 3.76Å; I162-L295 HydrophobicContact CD1-CG 3.69Å; I162-L295 HydrophobicContact CG1-CD2 4.17Å; I162-L295 HydrophobicContact CG2-CD2 4.32Å
163K93Very high88.3Confident97 Ų9794.2 Ų94.242%0.42244%0.438SS..EExtended strand (participates in β ladder)trans-115.4161.4176.6-63.9-171.1-177.5-1790110.9Y171 A173K163-Y171 HydrophobicContact CB-CD1 4.4Å; K163-Y171 HydrophobicContact CB-CE1 3.73Å; K163-Y171 HydrophobicContact CB-CE2 4.19Å; K163-Y171 PolarHBondContact N-O 3.34Å; K163-Y171 WeakPolarHBondContact O-CD1 3.41Å; K163-Y171 PolarHBondContact O-N 3.49Å; K163-Y171 VanDerWaalsContact O-O 3.06Å; K163-A173 HydrophobicContact CD-CB 3.89Å; K163-A173 HydrophobicContact CG-CB 4.17Å
164E90.5Very high88.4Confident91 Ų9196.7 Ų96.743%0.42546%0.464SS..EExtended strand (participates in β ladder)trans-117.5131.4178.8-75.4166-151.500108.5V170 R288 R294E164-V170 HydrophobicContact CG-CG2 4.12Å; E164-R288 IonicContact OE1-NH2 2.97Å; E164-R288 IonicContact OE2-NH2 3.7Å; E164-R288 PolarHBondContact OE2-NH2 3.11Å; E164-R294 IonicContact OE1-CZ 3.22Å; E164-R294 IonicContact OE1-NE 3.62Å; E164-R294 IonicContact OE1-NH2 3.67Å; E164-R294 PolarHBondContact OE1-NH2 2.87Å
165H85.2Confident88.7Confident82 Ų8285.6 Ų85.638%0.3842%0.424SS..EExtended strand (participates in β ladder)trans-120.5143.9172.9-171-81.3000109.2E167 R168 G169 Y171H165-E167 PolarHBondContact ND1-N 3.44Å; H165-E167 PolarHBondContact O-N 2.78Å; H165-R168 HydrophobicContact CB-CB 4.18Å; H165-R168 PolarHBondContact ND1-N 2.85Å; H165-G169 PolarHBondContact N-O 3.07Å; H165-G169 VanDerWaalsContact O-CA 3.3Å; H165-G169 WeakPolarHBondContact O-CA 3.31Å; H165-G169 PolarHBondContact O-N 3.24Å; H165-Y171 HydrophobicContact CB-CD1 4.04Å; H165-Y171 HydrophobicContact CB-CE1 3.69Å
166Q80.5Confident89Confident200 Ų20083 Ų8394%0.93541%0.412SS*.THydrogen-bonded Turntrans-59.5-45.9-177.3-69.5179-1900112.4
167E77.4Confident89.4Confident163 Ų16384.6 Ų84.676%0.76242%0.417SS*.THydrogen-bonded Turntrans-84.2-52.3179.4-60.3178.7164.400114.3H165 G169H165-E167 PolarHBondContact ND1-N 3.44Å; H165-E167 PolarHBondContact O-N 2.78Å; E167-G169 VanDerWaalsContact C-N 3.28Å; E167-G169 PolarHBondContact O-N 2.99Å
168R76.7Confident90Very high185 Ų18579.6 Ų79.670%0.69840%0.396SS*.THydrogen-bonded Turntrans-74.8-15.2-174.9-64.3-177179.1-176.5-1.8114.3H165 K235H165-R168 HydrophobicContact CB-CB 4.18Å; H165-R168 PolarHBondContact ND1-N 2.85Å; R168-K235 PolarHBondContact O-NZ 2.9Å
169G84.3Confident90.2Very high32 Ų3276.6 Ų76.633%0.3339%0.386SS..EExtended strand (participates in β ladder)trans76.3-148.6-172.900000112.7H165 E167H165-G169 PolarHBondContact N-O 3.07Å; H165-G169 VanDerWaalsContact O-CA 3.3Å; H165-G169 WeakPolarHBondContact O-CA 3.31Å; H165-G169 PolarHBondContact O-N 3.24Å; E167-G169 VanDerWaalsContact C-N 3.28Å; E167-G169 PolarHBondContact O-N 2.99Å
170V90.5Very high90.4Very high33 Ų3370.4 Ų70.420%0.236%0.36CS..EExtended strand (participates in β ladder)trans-72.7129.9177.3-172.50000109.8I162 E164 R294 L295I162-V170 HydrophobicContact CG2-CG1 3.31Å; E164-V170 HydrophobicContact CG-CG2 4.12Å; V170-R294 WeakPolarHBondContact CG1-O 3.42Å; V170-L295 HydrophobicContact CG1-CD2 4.41Å
171Y91.6Very high90.2Very high87 Ų8772.5 Ų72.534%0.34137%0.369SS..EExtended strand (participates in β ladder)trans-143.9158.5177.771.9-78.3000111.7K163 H165 A173K163-Y171 HydrophobicContact CB-CD1 4.4Å; K163-Y171 HydrophobicContact CB-CE1 3.73Å; K163-Y171 HydrophobicContact CB-CE2 4.19Å; K163-Y171 PolarHBondContact N-O 3.34Å; K163-Y171 WeakPolarHBondContact O-CD1 3.41Å; K163-Y171 PolarHBondContact O-N 3.49Å; K163-Y171 VanDerWaalsContact O-O 3.06Å; H165-Y171 HydrophobicContact CB-CD1 4.04Å; H165-Y171 HydrophobicContact CB-CE1 3.69Å; Y171-A173 HydrophobicContact CE2-CB 4.5Å
172V94.3Very high90.2Very high15 Ų1569 Ų699%0.09135%0.354CS..EExtended strand (participates in β ladder)trans-95.6120.8176.9-176.80000109L141 V148 L160 I162 L175 L295L141-V172 HydrophobicContact CD2-CG2 4.12Å; V148-V172 HydrophobicContact CG1-CG1 3.99Å; V148-V172 HydrophobicContact CG1-CG2 4.36Å; L160-V172 HydrophobicContact CB-CG1 3.59Å; L160-V172 HydrophobicContact CD1-CG1 3.8Å; L160-V172 HydrophobicContact CG-CG1 4.36Å; I162-V172 HydrophobicContact CG1-CG2 4.39Å; V172-L175 HydrophobicContact CB-CB 3.98Å; V172-L175 HydrophobicContact CB-CD2 4.23Å; V172-L175 HydrophobicContact CG1-CB 4.07Å; V172-L295 HydrophobicContact CG2-CD1 4.37Å; V172-L295 HydrophobicContact CG2-CD2 3.56Å
173A91.9Very high90.2Very high25 Ų2570 Ų7021%0.20736%0.361CS..EExtended strand (participates in β ladder)trans-73.5129.717900000110.5E161 K163 Y171 L175E161-A173 PolarHBondContact O-N 2.78Å; K163-A173 HydrophobicContact CD-CB 3.89Å; K163-A173 HydrophobicContact CG-CB 4.17Å; Y171-A173 HydrophobicContact CE2-CB 4.5Å; A173-L175 VanDerWaalsContact C-N 3.31Å
174G91Very high90.3Very high65 Ų6569.4 Ų69.467%0.6736%0.362SS*.THydrogen-bonded Turntrans80.75.2179.600000115.1S176G174-S176 PolarHBondContact O-N 2.9Å
175L94.4Very high90.6Very high32 Ų3267.9 Ų67.917%0.16836%0.355CS..  trans-64.5125.5173.5-177.165.1000110.1L141 D150 L160 V172 A173L141-L175 HydrophobicContact CB-CD1 4Å; L141-L175 HydrophobicContact CD2-CD1 4.31Å; L141-L175 HydrophobicContact CD2-CD2 3.99Å; D150-L175 HydrophobicContact CB-CD1 4.06Å; L160-L175 HydrophobicContact CD1-CB 4.33Å; L160-L175 HydrophobicContact CD1-CD1 4.3Å; V172-L175 HydrophobicContact CB-CB 3.98Å; V172-L175 HydrophobicContact CB-CD2 4.23Å; V172-L175 HydrophobicContact CG1-CB 4.07Å; A173-L175 VanDerWaalsContact C-N 3.31Å
176S94.6Very high91.1Very high28 Ų2864 Ų6420%0.19634%0.337CS..  trans-71137.4177.568.20000111.6S139 D150 G153 G174 H178S139-S176 WeakPolarHBondContact CB-O 3.31Å; D150-S176 VanDerWaalsContact CG-OG 3.3Å; D150-S176 PolarHBondContact OD1-OG 3.27Å; D150-S176 WeakPolarHBondContact OD2-CA 3.49Å; D150-S176 WeakPolarHBondContact OD2-CB 3.25Å; D150-S176 PolarHBondContact OD2-N 2.91Å; D150-S176 PolarHBondContact OD2-OG 2.86Å; G153-S176 PolarHBondContact N-OG 2.97Å; G174-S176 PolarHBondContact O-N 2.9Å; S176-H178 WeakPolarHBondContact CB-NE2 3.4Å; S176-H178 PolarHBondContact OG-NE2 2.67Å
177M94.4Very high91.7Very high81 Ų8157.2 Ų57.240%0.39931%0.306SS..  trans-117123.3178.1-63-65-67.200107.7C137 H218C137-M177 HydrophobicContact CB-CE 3.59Å; M177-H218 HydrophobicContact CE-CB 3.94Å; M177-H218 WeakPolarHBondContact CE-CD2 3.3Å; M177-H218 VanDerWaalsContact CE-CG 3.43Å
178H95.2Very high92.6Very high48 Ų4855.5 Ų55.522%0.22230%0.296CS..EExtended strand (participates in β ladder)trans-114.5114.1-176.6-61.9-95000109.1C137 A138 L152 S176 L189C137-H178 CarbonylContact C-O 3.16Å; C137-H178 WeakPolarHBondContact CA-O 3.39Å; A138-H178 PolarHBondContact N-O 3.02Å; A138-H178 PolarHBondContact O-N 2.91Å; L152-H178 WeakPolarHBondContact CB-NE2 3.29Å; S176-H178 WeakPolarHBondContact CB-NE2 3.4Å; S176-H178 PolarHBondContact OG-NE2 2.67Å; H178-L189 HydrophobicContact CB-CD1 3.71Å; H178-L189 HydrophobicContact CB-CD2 4.25Å
179P94.4Very high93.6Very high46 Ų4647.8 Ų47.830%0.29927%0.268SS..EExtended strand (participates in β ladder)trans-59.2140.4171.3-22.233.5000110.8I136 Q467I136-P179 WeakPolarHBondContact O-CA 3.45Å; P179-Q467 HydrophobicContact CB-CG 4.29Å
180V95Very high94.1Very high2 Ų246.8 Ų46.81%0.01226%0.255CS..  trans-135.1131.2-177.7-71.20000111F123 I136 A138 E185 C186 L189F123-V180 HydrophobicContact CZ-CB 4.36Å; F123-V180 HydrophobicContact CZ-CG2 4.15Å; I136-V180 HydrophobicContact CB-CG2 3.8Å; I136-V180 HydrophobicContact CG2-CG2 3.56Å; I136-V180 WeakPolarHBondContact O-CG2 3.08Å; I136-V180 PolarHBondContact O-N 3.37Å; A138-V180 HydrophobicContact CB-CG1 4.16Å; A138-V180 HydrophobicContact CB-CG2 4.45Å; V180-E185 HydrophobicContact CB-CB 4.5Å; V180-E185 HydrophobicContact CG1-CB 4.33Å; V180-C186 VanDerWaalsContact CG2-SG 3.54Å; V180-L189 HydrophobicContact CG1-CD1 3.42Å; V180-L189 VanDerWaalsContact CG1-CD1 3.42Å
181H91.9Very high94.3Very high61 Ų6147.9 Ų47.928%0.28226%0.258SS..  trans-108.7-21.5-172.8-47.383.5000112.9F123 E185 Q467 I469F123-H181 VanDerWaalsContact CE1-O 3.23Å; F123-H181 WeakPolarHBondContact CE1-O 3.07Å; H181-E185 IonicContact CE1-OE2 3.76Å; H181-E185 IonicContact CG-OE2 2.67Å; H181-E185 PolarHBondContact N-OE2 2.9Å; H181-E185 IonicContact ND1-OE1 3.35Å; H181-E185 IonicContact ND1-OE2 2.81Å; H181-E185 PolarHBondContact ND1-OE2 3.33Å; H181-Q467 WeakPolarHBondContact NE2-CA 3.36Å; H181-I469 HydrophobicContact CB-CG2 4.22Å
182N92.6Very high94.4Very high62 Ų6247.8 Ų47.833%0.33226%0.259SS..SBendtrans-148.4166.4-177.257.169.9000111.9N184 E185 C186N182-N184 VanDerWaalsContact C-N 3.28Å; N182-N184 PolarHBondContact O-N 3.4Å; N182-N184 WeakPolarHBondContact OD1-CB 3.37Å; N182-N184 PolarHBondContact OD1-N 2.76Å; N182-E185 PolarHBondContact ND2-OE1 2.75Å; N182-E185 PolarHBondContact O-N 2.86Å; N182-E185 PolarHBondContact OD1-N 3.22Å; N182-C186 PolarHBondContact O-N 3.02Å
183V94.8Very high94.4Very high34 Ų3447 Ų4721%0.20626%0.255CS..Hα-helixtrans-56.9-41-179.7-179.40000111.9F119 E120 F123 E185 C186 E187F119-V183 HydrophobicContact CB-CG1 4.08Å; E120-V183 HydrophobicContact CG-CG1 4.07Å; F123-V183 HydrophobicContact CB-CG2 3.8Å; F123-V183 HydrophobicContact CD2-CB 4.43Å; F123-V183 HydrophobicContact CD2-CG2 3.7Å; F123-V183 HydrophobicContact CG-CG2 4.06Å; V183-E185 PolarHBondContact O-N 2.93Å; V183-C186 WeakPolarHBondContact O-CB 3.33Å; V183-C186 PolarHBondContact O-N 3.38Å; V183-E187 HydrophobicContact CG1-CG 4.28Å; V183-E187 WeakPolarHBondContact O-CG 3.43Å; V183-E187 PolarHBondContact O-N 3.39Å
184N95.5Very high94.3Very high85 Ų8548.1 Ų48.146%0.45526%0.256SS..Hα-helixtrans-66-35.9-176.7-177.340.7000112.2N182 E187 K188N182-N184 VanDerWaalsContact C-N 3.28Å; N182-N184 PolarHBondContact O-N 3.4Å; N182-N184 WeakPolarHBondContact OD1-CB 3.37Å; N182-N184 PolarHBondContact OD1-N 2.76Å; N184-E187 PolarHBondContact O-N 2.95Å; N184-K188 WeakPolarHBondContact ND2-CE 3.09Å; N184-K188 PolarHBondContact ND2-NZ 2.89Å; N184-K188 WeakPolarHBondContact O-CB 3.24Å; N184-K188 VanDerWaalsContact O-CG 3.24Å; N184-K188 WeakPolarHBondContact O-CG 3.47Å; N184-K188 PolarHBondContact O-N 3.4Å
185E95.7Very high94.3Very high59 Ų5953.2 Ų53.228%0.27626%0.255SS..Hα-helixtrans-63.5-44.6172.2-78.1169.1-153.900111.8V180 H181 N182 V183 E187 K188 L189V180-E185 HydrophobicContact CB-CB 4.5Å; V180-E185 HydrophobicContact CG1-CB 4.33Å; H181-E185 IonicContact CE1-OE2 3.76Å; H181-E185 IonicContact CG-OE2 2.67Å; H181-E185 PolarHBondContact N-OE2 2.9Å; H181-E185 IonicContact ND1-OE1 3.35Å; H181-E185 IonicContact ND1-OE2 2.81Å; H181-E185 PolarHBondContact ND1-OE2 3.33Å; N182-E185 PolarHBondContact ND2-OE1 2.75Å; N182-E185 PolarHBondContact O-N 2.86Å; N182-E185 PolarHBondContact OD1-N 3.22Å; V183-E185 PolarHBondContact O-N 2.93Å; E185-E187 PolarHBondContact O-N 3.22Å; E185-K188 PolarHBondContact O-N 2.94Å; E185-L189 WeakPolarHBondContact O-CG 3.45Å; E185-L189 PolarHBondContact O-N 3.29Å
186C95.2Very high94.1Very high0 Ų053.7 Ų53.70%026%0.258CS..Hα-helixtrans-60.8-44.6174-750000112.3F119 V180 N182 V183 K188 L189 L190F119-C186 HydrophobicContact CB-CB 4.3Å; F119-C186 HydrophobicContact CD1-CB 4.13Å; F119-C186 HydrophobicContact CD2-CB 3.52Å; F119-C186 HydrophobicContact CE1-CB 4.33Å; F119-C186 HydrophobicContact CE2-CB 3.74Å; F119-C186 HydrophobicContact CG-CB 3.73Å; F119-C186 HydrophobicContact CZ-CB 4.14Å; V180-C186 VanDerWaalsContact CG2-SG 3.54Å; N182-C186 PolarHBondContact O-N 3.02Å; V183-C186 WeakPolarHBondContact O-CB 3.33Å; V183-C186 PolarHBondContact O-N 3.38Å; C186-K188 PolarHBondContact O-N 3.47Å; C186-L189 PolarHBondContact O-N 3.07Å; C186-L190 WeakPolarHBondContact O-CB 3.36Å; C186-L190 PolarHBondContact O-N 3.21Å
187E95Very high93.8Very high59 Ų5953 Ų5328%0.27625%0.251SS..Hα-helixtrans-63.5-40177.3-72.7-177.5163.200111.5K112 F119 V183 N184 E185 L189 L190 Q191K112-E187 IonicContact NZ-OE1 3.86Å; K112-E187 PolarHBondContact NZ-OE1 3.37Å; F119-E187 HydrophobicContact CD2-CG 4.17Å; V183-E187 HydrophobicContact CG1-CG 4.28Å; V183-E187 WeakPolarHBondContact O-CG 3.43Å; V183-E187 PolarHBondContact O-N 3.39Å; N184-E187 PolarHBondContact O-N 2.95Å; E185-E187 PolarHBondContact O-N 3.22Å; E187-L189 PolarHBondContact O-N 2.87Å; E187-L190 PolarHBondContact O-N 3.4Å; E187-Q191 WeakPolarHBondContact O-CB 3.33Å; E187-Q191 VanDerWaalsContact O-CG 3.24Å; E187-Q191 WeakPolarHBondContact O-CG 3.34Å; E187-Q191 PolarHBondContact O-N 2.85Å
188K96.3Very high93.1Very high126 Ų12651.9 Ų51.955%0.54825%0.254SS..Hα-helixtrans-61.2-43.6173.3-75.8169.8-176.3173.10112.3N184 E185 C186 Q191 K192N184-K188 WeakPolarHBondContact ND2-CE 3.09Å; N184-K188 PolarHBondContact ND2-NZ 2.89Å; N184-K188 WeakPolarHBondContact O-CB 3.24Å; N184-K188 VanDerWaalsContact O-CG 3.24Å; N184-K188 WeakPolarHBondContact O-CG 3.47Å; N184-K188 PolarHBondContact O-N 3.4Å; E185-K188 PolarHBondContact O-N 2.94Å; C186-K188 PolarHBondContact O-N 3.47Å; K188-Q191 PolarHBondContact O-N 2.82Å; K188-K192 VanDerWaalsContact O-CB 3.29Å; K188-K192 WeakPolarHBondContact O-CB 3.37Å; K188-K192 PolarHBondContact O-N 2.89Å
189L96.7Very high91.9Very high24 Ų2453.3 Ų53.313%0.12627%0.267CS..Hα-helixtrans-64.8-43176.3-69.8177.8000111.4A138 L152 H178 V180 E185 C186 E187 K192 G193A138-L189 HydrophobicContact CB-CD1 3.92Å; L152-L189 HydrophobicContact CD1-CB 4.37Å; L152-L189 HydrophobicContact CD1-CD2 4.36Å; L152-L189 HydrophobicContact CD2-CB 4.25Å; L152-L189 HydrophobicContact CD2-CD2 4.35Å; L152-L189 VanDerWaalsContact CD2-O 3.22Å; L152-L189 WeakPolarHBondContact CD2-O 3.33Å; H178-L189 HydrophobicContact CB-CD1 3.71Å; H178-L189 HydrophobicContact CB-CD2 4.25Å; V180-L189 HydrophobicContact CG1-CD1 3.42Å; V180-L189 VanDerWaalsContact CG1-CD1 3.42Å; E185-L189 WeakPolarHBondContact O-CG 3.45Å; E185-L189 PolarHBondContact O-N 3.29Å; C186-L189 PolarHBondContact O-N 3.07Å; E187-L189 PolarHBondContact O-N 2.87Å; L189-K192 PolarHBondContact O-N 2.84Å; L189-G193 PolarHBondContact O-N 2.83Å
190L95.4Very high90.3Very high10 Ų1052.8 Ų52.85%0.05227%0.266CS..Hα-helixtrans-57.8-51.6175.218064.7000110.8V115 F119 Y140 C186 E187 K192 G193 M194 F215V115-L190 HydrophobicContact CG1-CD1 4.09Å; V115-L190 HydrophobicContact CG1-CD2 3.86Å; F119-L190 HydrophobicContact CE2-CB 4.28Å; F119-L190 HydrophobicContact CE2-CD2 4.06Å; Y140-L190 HydrophobicContact CE1-CD1 4.22Å; C186-L190 WeakPolarHBondContact O-CB 3.36Å; C186-L190 PolarHBondContact O-N 3.21Å; E187-L190 PolarHBondContact O-N 3.4Å; L190-K192 PolarHBondContact O-N 3.01Å; L190-G193 PolarHBondContact O-N 3.44Å; L190-M194 HydrophobicContact CD1-CG 4.43Å; L190-M194 HydrophobicContact CD1-SD 4.28Å; L190-M194 HydrophobicContact CG-SD 3.99Å; L190-M194 WeakPolarHBondContact O-CB 3.29Å; L190-M194 VanDerWaalsContact O-CG 3.28Å; L190-M194 WeakPolarHBondContact O-CG 3.32Å; L190-M194 PolarHBondContact O-N 3.22Å; L190-F215 HydrophobicContact CB-CE2 4.42Å; L190-F215 HydrophobicContact CD1-CD2 4.12Å; L190-F215 HydrophobicContact CD1-CE2 4.39Å
191Q94.1Very high88.4Confident56 Ų5653.9 Ų53.926%0.26228%0.275SS..Hα-helixtrans-62.8-40.7179.2-70.4-67.4-14.200112.3E187 K188 M194 R195E187-Q191 WeakPolarHBondContact O-CB 3.33Å; E187-Q191 VanDerWaalsContact O-CG 3.24Å; E187-Q191 WeakPolarHBondContact O-CG 3.34Å; E187-Q191 PolarHBondContact O-N 2.85Å; K188-Q191 PolarHBondContact O-N 2.82Å; Q191-M194 PolarHBondContact O-N 3.16Å; Q191-R195 VanDerWaalsContact O-CG 3.29Å; Q191-R195 WeakPolarHBondContact O-CG 3.35Å; Q191-R195 PolarHBondContact O-N 3.08Å
192K94.4Very high86.6Confident85 Ų8556.4 Ų56.437%0.3730%0.295SS..Hα-helixtrans-58.4-50.2173.4-179.8-174.1174.8-165.50110.8L152 K188 L189 L190 M194 R195 N196L152-K192 PolarHBondContact O-NZ 3.04Å; K188-K192 VanDerWaalsContact O-CB 3.29Å; K188-K192 WeakPolarHBondContact O-CB 3.37Å; K188-K192 PolarHBondContact O-N 2.89Å; L189-K192 PolarHBondContact O-N 2.84Å; L190-K192 PolarHBondContact O-N 3.01Å; K192-M194 PolarHBondContact O-N 2.94Å; K192-R195 PolarHBondContact O-N 3.15Å; K192-N196 VanDerWaalsContact O-CG 3.32Å; K192-N196 PolarHBondContact O-N 3.32Å
193G93.3Very high84.5Confident0 Ų059.3 Ų59.30%031%0.31CS..Hα-helixtrans-66.6-36.118000000113.2L189 L190 N196 R197L189-G193 PolarHBondContact O-N 2.83Å; L190-G193 PolarHBondContact O-N 3.44Å; G193-N196 PolarHBondContact O-N 2.8Å; G193-R197 WeakPolarHBondContact O-CB 3.42Å; G193-R197 PolarHBondContact O-N 2.74Å
194M91Very high82.1Confident48 Ų4865.1 Ų65.124%0.23634%0.337CS..Hα-helixtrans-63.2-43.4174-74.4176.564.900112.1Q103 Y140 L190 Q191 K192 N196 R197 A198Q103-M194 HydrophobicContact CG-SD 4.44Å; Y140-M194 HydrophobicContact CE1-CG 4.46Å; L190-M194 HydrophobicContact CD1-CG 4.43Å; L190-M194 HydrophobicContact CD1-SD 4.28Å; L190-M194 HydrophobicContact CG-SD 3.99Å; L190-M194 WeakPolarHBondContact O-CB 3.29Å; L190-M194 VanDerWaalsContact O-CG 3.28Å; L190-M194 WeakPolarHBondContact O-CG 3.32Å; L190-M194 PolarHBondContact O-N 3.22Å; Q191-M194 PolarHBondContact O-N 3.16Å; K192-M194 PolarHBondContact O-N 2.94Å; M194-N196 VanDerWaalsContact C-N 3.34Å; M194-R197 PolarHBondContact O-N 3.25Å; M194-A198 WeakPolarHBondContact O-CB 3.47Å; M194-A198 PolarHBondContact O-N 2.73Å
195R90.1Very high80.1Confident171 Ų17166.1 Ų66.165%0.64534%0.342SS*.Hα-helixtrans-62.9-41.7174.6-70.7172.1-168.91763.3111.7Q191 K192 A198 T199Q191-R195 VanDerWaalsContact O-CG 3.29Å; Q191-R195 WeakPolarHBondContact O-CG 3.35Å; Q191-R195 PolarHBondContact O-N 3.08Å; K192-R195 PolarHBondContact O-N 3.15Å; R195-A198 PolarHBondContact O-N 3.04Å; R195-T199 WeakPolarHBondContact O-CB 3.36Å; R195-T199 PolarHBondContact O-N 3.31Å; R195-T199 PolarHBondContact O-OG1 3.25Å
196N90.5Very high78.2Confident43 Ų4364.1 Ų64.123%0.2333%0.334CS..Hα-helixtrans-64.9-40.7177.4-72.7-15.2000111.7L151 T156 K192 G193 M194 T199 A200L151-N196 HydrophobicContact CD2-CB 4.38Å; L151-N196 PolarHBondContact O-ND2 3.47Å; T156-N196 HydrophobicContact CG2-CB 4.07Å; K192-N196 VanDerWaalsContact O-CG 3.32Å; K192-N196 PolarHBondContact O-N 3.32Å; G193-N196 PolarHBondContact O-N 2.8Å; M194-N196 VanDerWaalsContact C-N 3.34Å; N196-T199 PolarHBondContact O-N 3.37Å; N196-A200 PolarHBondContact O-N 2.91Å; N196-A200 VanDerWaalsContact O-N 3.14Å
197R89Confident77Confident14 Ų1467.7 Ų67.75%0.05335%0.353CS..Hα-helixtrans-61.8-45.2172.9-172.2-179.1-179-166.10.6111.8E142 L151 G193 M194 A200 S208 S211 S213 D240E142-R197 WeakPolarHBondContact OE1-CG 3.46Å; E142-R197 IonicContact OE1-NE 3.76Å; L151-R197 HydrophobicContact CD1-CB 4.25Å; L151-R197 HydrophobicContact CD2-CB 4Å; G193-R197 WeakPolarHBondContact O-CB 3.42Å; G193-R197 PolarHBondContact O-N 2.74Å; M194-R197 PolarHBondContact O-N 3.25Å; R197-A200 PolarHBondContact O-N 3.12Å; R197-S208 PolarHBondContact NH2-O 3.22Å; R197-S211 PolarHBondContact NE-OG 3.37Å; R197-S211 PolarHBondContact NH2-O 3.16Å; R197-S211 PolarHBondContact NH2-OG 3.37Å; R197-S213 PolarHBondContact NH1-OG 3.12Å; R197-S213 VanDerWaalsContact NH1-OG 3.15Å; R197-D240 IonicContact NH1-OD2 2.84Å
198A79Confident76.2Confident56 Ų5667.5 Ų67.546%0.46336%0.359SS..Hα-helixtrans-69.8-34.7178.600000113M194 R195 A200 A201M194-A198 WeakPolarHBondContact O-CB 3.47Å; M194-A198 PolarHBondContact O-N 2.73Å; R195-A198 PolarHBondContact O-N 3.04Å; A198-A200 VanDerWaalsContact C-N 3.33Å; A198-A201 WeakPolarHBondContact O-CA 3.34Å; A198-A201 WeakPolarHBondContact O-CB 3.3Å; A198-A201 PolarHBondContact O-N 3.17Å
199T70.1Confident75.6Confident79 Ų7962.6 Ų62.649%0.48534%0.34SS..Hα-helixtrans-71.1-30.7178.4-53.90000111.6R195 N196 A201 T202R195-T199 WeakPolarHBondContact O-CB 3.36Å; R195-T199 PolarHBondContact O-N 3.31Å; R195-T199 PolarHBondContact O-OG1 3.25Å; N196-T199 PolarHBondContact O-N 3.37Å; T199-A201 PolarHBondContact O-N 3.28Å; T199-T202 PolarHBondContact O-N 2.88Å; T199-T202 PolarHBondContact O-OG1 3.24Å
200A60.3Low75Confident34 Ų3463.2 Ų63.228%0.28134%0.341SS..Hα-helixtrans-58.9-30.8168.700000111.6N196 R197 A198 T206N196-A200 PolarHBondContact O-N 2.91Å; N196-A200 VanDerWaalsContact O-N 3.14Å; R197-A200 PolarHBondContact O-N 3.12Å; A198-A200 VanDerWaalsContact C-N 3.33Å; A200-T206 WeakPolarHBondContact O-CB 3.17Å
201A56.1Low74.8Confident25 Ų2562.8 Ų62.821%0.20734%0.338CS..Hα-helixtrans-64.2-41.3177.800000114.6A198 T199 L203 N205 T206A198-A201 WeakPolarHBondContact O-CA 3.34Å; A198-A201 WeakPolarHBondContact O-CB 3.3Å; A198-A201 PolarHBondContact O-N 3.17Å; T199-A201 PolarHBondContact O-N 3.28Å; A201-L203 PolarHBondContact O-N 2.93Å; A201-N205 WeakPolarHBondContact O-CA 3.45Å; A201-N205 PolarHBondContact O-N 3.43Å; A201-T206 WeakPolarHBondContact CA-O 3.5Å; A201-T206 WeakPolarHBondContact CB-O 3.47Å; A201-T206 PolarHBondContact O-N 3.35Å; A201-T206 VanDerWaalsContact O-N 3.11Å
202T52.5Low74.8Confident114 Ų11460.3 Ų60.370%0.69933%0.327SS*.Hα-helixtrans-75.8-24.6-169.754.70000113.3T199 M204T199-T202 PolarHBondContact O-N 2.88Å; T199-T202 PolarHBondContact O-OG1 3.24Å; T202-M204 PolarHBondContact O-N 2.89Å
203L48.8Very low74.8Confident123 Ų12356.4 Ų56.464%0.64431%0.311SS*.THydrogen-bonded Turntrans-75.6-21.1-177.7-83.3157.5000113.6A201A201-L203 PolarHBondContact O-N 2.93Å
204M45.5Very low74.9Confident156 Ų15656.7 Ų56.777%0.76831%0.312SS*.THydrogen-bonded Turntrans-168.660173.2-151.8172.1-85.800113.2T202 T206T202-M204 PolarHBondContact O-N 2.89Å; M204-T206 PolarHBondContact O-N 3.34Å
205N53Low75.2Confident107 Ų10754.6 Ų54.657%0.57230%0.301SS*.THydrogen-bonded Turntrans48.834177.2-61.3-61.4000115.5A201 D207 R256A201-N205 WeakPolarHBondContact O-CA 3.45Å; A201-N205 PolarHBondContact O-N 3.43Å; N205-D207 PolarHBondContact O-N 2.88Å; N205-R256 PolarHBondContact ND2-NH2 3.43Å
206T55.6Low75.6Confident17 Ų1746.6 Ų46.610%0.10427%0.272CS..  trans-78.784.5176.3-60.90000109.4Y144 A200 A201 M204 S208Y144-T206 HydrophobicContact CD1-CG2 4.13Å; Y144-T206 HydrophobicContact CD2-CG2 3.95Å; Y144-T206 HydrophobicContact CE1-CG2 3.73Å; Y144-T206 HydrophobicContact CE2-CG2 3.58Å; Y144-T206 HydrophobicContact CG-CG2 4.2Å; Y144-T206 VanDerWaalsContact CZ-CG2 3.43Å; Y144-T206 PolarHBondContact OH-OG1 3.26Å; A200-T206 WeakPolarHBondContact O-CB 3.17Å; A201-T206 WeakPolarHBondContact CA-O 3.5Å; A201-T206 WeakPolarHBondContact CB-O 3.47Å; A201-T206 PolarHBondContact O-N 3.35Å; A201-T206 VanDerWaalsContact O-N 3.11Å; M204-T206 PolarHBondContact O-N 3.34Å; T206-S208 PolarHBondContact O-N 2.58Å
207D69.5Low75.9Confident74 Ų7444.7 Ų44.740%0.39626%0.261SS..  trans-61128.2178.6-171.5-6000110.9N205 S209 R210N205-D207 PolarHBondContact O-N 2.88Å; D207-S209 PolarHBondContact O-N 3.01Å; D207-S209 VanDerWaalsContact O-N 3.07Å; D207-S209 WeakPolarHBondContact OD1-CB 3.37Å; D207-S209 PolarHBondContact OD1-N 3.26Å; D207-S209 PolarHBondContact OD1-OG 2.96Å; D207-S209 WeakPolarHBondContact OD2-CB 3.35Å; D207-S209 PolarHBondContact OD2-OG 2.82Å; D207-R210 HydrophobicContact CB-CG 4.3Å; D207-R210 WeakPolarHBondContact O-CB 3.4Å; D207-R210 PolarHBondContact O-N 3.35Å
208S79.5Confident76.3Confident56 Ų5646.1 Ų46.139%0.39227%0.269SS..G310 helixtrans-56.1-22172.663.40000112.9R197 T206 R210 S211R197-S208 PolarHBondContact NH2-O 3.22Å; T206-S208 PolarHBondContact O-N 2.58Å; S208-R210 PolarHBondContact O-N 3.28Å; S208-S211 PolarHBondContact O-N 2.79Å; S208-S211 PolarHBondContact O-OG 2.83Å
209S83.2Confident77Confident23 Ų2343.5 Ų43.516%0.16125%0.247CC..G310 helixtrans-64-20.3173.3760000113.9D207 A242 G243D207-S209 PolarHBondContact O-N 3.01Å; D207-S209 VanDerWaalsContact O-N 3.07Å; D207-S209 WeakPolarHBondContact OD1-CB 3.37Å; D207-S209 PolarHBondContact OD1-N 3.26Å; D207-S209 PolarHBondContact OD1-OG 2.96Å; D207-S209 WeakPolarHBondContact OD2-CB 3.35Å; D207-S209 PolarHBondContact OD2-OG 2.82Å; S209-A242 CarbonylContact O-C 3.6Å; S209-A242 VanDerWaalsContact O-CA 3.32Å; S209-A242 WeakPolarHBondContact O-CA 3.42Å; S209-G243 PolarHBondContact O-N 2.9Å
210R84.9Confident78.1Confident37 Ų3743.8 Ų43.814%0.1424%0.243CC..G310 helixtrans-99.1-4.5-175.2-68.9-179.4171.8-158.7-6.3114Y144 D207 S208 E259 I263Y144-R210 HydrophobicContact CD2-CB 4.48Å; Y144-R210 HydrophobicContact CE2-CB 4.13Å; D207-R210 HydrophobicContact CB-CG 4.3Å; D207-R210 WeakPolarHBondContact O-CB 3.4Å; D207-R210 PolarHBondContact O-N 3.35Å; S208-R210 PolarHBondContact O-N 3.28Å; R210-E259 VanDerWaalsContact CD-OE1 3.24Å; R210-E259 WeakPolarHBondContact CD-OE1 3.42Å; R210-E259 IonicContact CZ-OE1 3.84Å; R210-E259 IonicContact NH1-OE1 2.73Å; R210-E259 PolarHBondContact NH1-OE1 2.63Å; R210-E259 IonicContact NH1-OE2 3.71Å; R210-E259 PolarHBondContact NH1-OE2 2.87Å; R210-E259 VanDerWaalsContact NH1-OE2 3.07Å; R210-I263 HydrophobicContact CB-CD1 3.54Å; R210-I263 HydrophobicContact CB-CG1 4.34Å; R210-I263 HydrophobicContact CG-CD1 3.71Å
211S90.2Very high79.7Confident0 Ų042.4 Ų42.40%023%0.231CC..SBendtrans-110.4145.4176.859.60000111.7E142 I143 R197 S208E142-S211 WeakPolarHBondContact OE1-CB 3.23Å; E142-S211 PolarHBondContact OE1-OG 3Å; I143-S211 WeakPolarHBondContact O-CA 3.49Å; R197-S211 PolarHBondContact NE-OG 3.37Å; R197-S211 PolarHBondContact NH2-O 3.16Å; R197-S211 PolarHBondContact NH2-OG 3.37Å; S208-S211 PolarHBondContact O-N 2.79Å; S208-S211 PolarHBondContact O-OG 2.83Å
212H93.4Very high81.3Confident4 Ų443.5 Ų43.52%0.01923%0.231CC..EExtended strand (participates in β ladder)trans-85.8136.7167.7-51.1-77000108.3E142 I143 D240 L241 A242 S266 L292E142-H212 CarbonylContact C-O 3.58Å; E142-H212 VanDerWaalsContact CA-O 3.31Å; E142-H212 WeakPolarHBondContact CA-O 3.47Å; I143-H212 HydrophobicContact CB-CB 4.23Å; I143-H212 PolarHBondContact N-O 3.32Å; I143-H212 PolarHBondContact O-N 2.92Å; H212-D240 WeakPolarHBondContact CA-O 3.48Å; H212-L241 HydrophobicContact CB-CD2 4.48Å; H212-L241 WeakPolarHBondContact ND1-CA 3.38Å; H212-L241 WeakPolarHBondContact ND1-CD2 3.38Å; H212-A242 WeakPolarHBondContact CE1-CB 3.5Å; H212-A242 PolarHBondContact CE1-N 3.06Å; H212-A242 PolarHBondContact ND1-N 2.91Å; H212-S266 PolarHBondContact NE2-OG 3.3Å; H212-L292 HydrophobicContact CB-CD1 4.29Å
213S94.3Very high82.9Confident4 Ų440.8 Ų40.83%0.02821%0.21CC..EExtended strand (participates in β ladder)trans-119.7131.9173.682.30000110.2Y140 L141 R197 V239 D240Y140-S213 PolarHBondContact OH-OG 3.06Å; L141-S213 WeakPolarHBondContact O-CA 3.49Å; R197-S213 PolarHBondContact NH1-OG 3.12Å; R197-S213 VanDerWaalsContact NH1-OG 3.15Å; S213-V239 WeakPolarHBondContact O-CA 3.43Å; S213-D240 PolarHBondContact N-O 2.79Å; S213-D240 PolarHBondContact O-N 2.94Å
214I96.9Very high84.5Confident5 Ų538.5 Ų38.53%0.02620%0.201CC..EExtended strand (participates in β ladder)trans-125.2104.4-177.1-57-178.5000107.4Y140 L141 I143 V239 L292 L295Y140-I214 WeakPolarHBondContact CD2-O 3.32Å; L141-I214 HydrophobicContact CD1-CB 3.84Å; L141-I214 HydrophobicContact CD1-CD1 4.08Å; L141-I214 HydrophobicContact CD1-CG1 4.09Å; L141-I214 HydrophobicContact CG-CB 4Å; L141-I214 PolarHBondContact N-O 3.36Å; L141-I214 PolarHBondContact O-N 2.96Å; I143-I214 HydrophobicContact CD1-CD1 4.12Å; I214-V239 HydrophobicContact CG1-CG1 4Å; I214-V239 HydrophobicContact CG1-CG2 4.11Å; I214-V239 HydrophobicContact CG2-CG2 4.15Å; I214-L292 HydrophobicContact CD1-CD1 4.21Å; I214-L295 HydrophobicContact CD1-CB 4.45Å; I214-L295 HydrophobicContact CD1-CD1 4.1Å
215F97.5Very high85.8Confident4 Ų435.6 Ų35.62%0.01819%0.185CC..EExtended strand (participates in β ladder)trans-92.1122.1169.7-168.3-81.1000108.2F119 A138 Y140 L190 L217 L238F119-F215 HydrophobicContact CE1-CD1 4.13Å; F119-F215 AromaticContact CE1-CE1 3.49Å; F119-F215 HydrophobicContact CE1-CE1 3.49Å; F119-F215 VanDerWaalsContact CE1-CE1 3.49Å; F119-F215 HydrophobicContact CE1-CZ 4.04Å; F119-F215 HydrophobicContact CZ-CD1 4.13Å; F119-F215 AromaticContact CZ-CE1 3.49Å; F119-F215 HydrophobicContact CZ-CE1 3.49Å; F119-F215 VanDerWaalsContact CZ-CE1 3.49Å; F119-F215 HydrophobicContact CZ-CE2 4.33Å; F119-F215 AromaticContact CZ-CZ 3.61Å; F119-F215 HydrophobicContact CZ-CZ 3.61Å; A138-F215 HydrophobicContact CB-CE1 4.31Å; A138-F215 HydrophobicContact CB-CZ 3.93Å; Y140-F215 AromaticContact CD1-CD2 3.86Å; Y140-F215 HydrophobicContact CD1-CD2 3.86Å; Y140-F215 HydrophobicContact CD1-CE2 4.41Å; Y140-F215 HydrophobicContact CD2-CB 3.86Å; Y140-F215 AromaticContact CD2-CD2 3.89Å; Y140-F215 HydrophobicContact CD2-CD2 3.89Å; Y140-F215 HydrophobicContact CD2-CG 4.36Å; Y140-F215 HydrophobicContact CE1-CD2 4.47Å; Y140-F215 HydrophobicContact CE2-CB 4.12Å; Y140-F215 HydrophobicContact CE2-CD2 4.45Å; Y140-F215 HydrophobicContact CG-CB 4.41Å; Y140-F215 AromaticContact CG-CD2 3.57Å; Y140-F215 HydrophobicContact CG-CD2 3.57Å; Y140-F215 HydrophobicContact CG-CE2 4.33Å; Y140-F215 HydrophobicContact CG-CG 4.44Å; L190-F215 HydrophobicContact CB-CE2 4.42Å; L190-F215 HydrophobicContact CD1-CD2 4.12Å; L190-F215 HydrophobicContact CD1-CE2 4.39Å; F215-L217 HydrophobicContact CD1-CG 4.43Å; F215-L217 HydrophobicContact CE1-CD2 3.72Å; F215-L217 HydrophobicContact CE1-CG 3.95Å; F215-L217 HydrophobicContact CZ-CD2 4.48Å; F215-L238 HydrophobicContact CB-CB 4.39Å; F215-L238 HydrophobicContact CD1-CD1 4.39Å; F215-L238 PolarHBondContact N-O 3.37Å; F215-L238 PolarHBondContact O-N 3.45Å
216T97.6Very high86.7Confident4 Ų438.7 Ų38.73%0.02520%0.196CC..EExtended strand (participates in β ladder)trans-118.8128.8-177.9-52.10000110.7A138 S139 H218 L236 H237A138-T216 WeakPolarHBondContact CA-O 3.4Å; S139-T216 PolarHBondContact N-O 3.44Å; S139-T216 PolarHBondContact O-N 3.39Å; T216-H218 VanDerWaalsContact CG2-NE2 3.32Å; T216-H218 WeakPolarHBondContact CG2-NE2 3.25Å; T216-L236 VanDerWaalsContact CA-O 3.32Å; T216-L236 WeakPolarHBondContact CA-O 3.47Å; T216-H237 VanDerWaalsContact CG2-CE1 3.41Å; T216-H237 WeakPolarHBondContact CG2-CE1 3.49Å; T216-H237 WeakPolarHBondContact CG2-ND1 3.43Å; T216-H237 PolarHBondContact OG1-ND1 3.02Å
217L97.4Very high87.3Confident2 Ų241.4 Ų41.41%0.0123%0.228CC..EExtended strand (participates in β ladder)trans-99.5126165.2-66.4173.8000109.2T118 F119 I122 I136 A138 F215 L219 K235 L236T118-L217 HydrophobicContact CG2-CD1 4.34Å; F119-L217 HydrophobicContact CD1-CD1 3.96Å; F119-L217 HydrophobicContact CE1-CD1 3.98Å; F119-L217 HydrophobicContact CE1-CD2 4.45Å; F119-L217 HydrophobicContact CE1-CG 4.45Å; I122-L217 HydrophobicContact CD1-CD1 3.52Å; I136-L217 HydrophobicContact CG2-CD2 4.1Å; A138-L217 HydrophobicContact CB-CD2 3.95Å; F215-L217 HydrophobicContact CD1-CG 4.43Å; F215-L217 HydrophobicContact CE1-CD2 3.72Å; F215-L217 HydrophobicContact CE1-CG 3.95Å; F215-L217 HydrophobicContact CZ-CD2 4.48Å; L217-L219 HydrophobicContact CB-CD1 3.88Å; L217-K235 CarbonylContact O-C 3.55Å; L217-K235 WeakPolarHBondContact O-CA 3.44Å; L217-L236 HydrophobicContact CB-CB 4.36Å; L217-L236 PolarHBondContact N-O 2.94Å; L217-L236 PolarHBondContact O-N 3.41Å
218H96Very high87.5Confident45 Ų4544.7 Ų44.721%0.20824%0.235CC..EExtended strand (participates in β ladder)trans-103.1120.4172.4-62.7-99.7000107.6I136 C137 M177 T216I136-H218 CarbonylContact C-O 3.59Å; I136-H218 WeakPolarHBondContact CA-O 3.26Å; C137-H218 HydrophobicContact CB-CB 4.25Å; C137-H218 PolarHBondContact N-O 3.33Å; C137-H218 PolarHBondContact O-N 2.94Å; M177-H218 HydrophobicContact CE-CB 3.94Å; M177-H218 WeakPolarHBondContact CE-CD2 3.3Å; M177-H218 VanDerWaalsContact CE-CG 3.43Å; T216-H218 VanDerWaalsContact CG2-NE2 3.32Å; T216-H218 WeakPolarHBondContact CG2-NE2 3.25Å
219L95.4Very high87.4Confident1 Ų148.8 Ų48.81%0.00525%0.248CC..EExtended strand (participates in β ladder)trans-113.1125.9179.9-68.181.5000108.4V80 L81 I122 I136 L217 M221 T233 A234V80-L219 HydrophobicContact CG1-CD1 3.94Å; V80-L219 HydrophobicContact CG1-CD2 4.19Å; L81-L219 HydrophobicContact CD2-CD2 4.06Å; I122-L219 HydrophobicContact CG2-CD2 4.28Å; I136-L219 HydrophobicContact CG1-CG 4.49Å; L217-L219 HydrophobicContact CB-CD1 3.88Å; L219-M221 HydrophobicContact CB-CE 4.39Å; L219-T233 CarbonylContact O-C 3.46Å; L219-T233 WeakPolarHBondContact O-CA 3.5Å; L219-A234 HydrophobicContact CB-CB 4.4Å; L219-A234 PolarHBondContact N-O 3Å; L219-A234 PolarHBondContact O-N 2.68Å
220E93.4Very high87.5Confident84 Ų8450.2 Ų50.239%0.39325%0.252SS..EExtended strand (participates in β ladder)trans-113.3130.3167.4-57.4-175.8173.400107.8F134 L135 F222 T233F134-E220 CarbonylContact C-O 3.36Å; F134-E220 VanDerWaalsContact CA-O 3.31Å; F134-E220 WeakPolarHBondContact CA-O 3.41Å; L135-E220 HydrophobicContact CB-CB 4.3Å; L135-E220 PolarHBondContact N-O 3.13Å; L135-E220 PolarHBondContact O-N 3.42Å; E220-F222 HydrophobicContact CB-CE2 4.23Å; E220-F222 HydrophobicContact CB-CZ 4.25Å; E220-T233 HydrophobicContact CG-CG2 4.22Å
221M92.7Very high87.7Confident6 Ų650.9 Ų50.93%0.0326%0.257CS..EExtended strand (participates in β ladder)trans-120124.7-172.7-64170.6-113.700108.7V80 V132 K133 F134 L219 I231 K232 A234V80-M221 WeakPolarHBondContact O-CE 3.38Å; V132-M221 HydrophobicContact CG1-CB 4.13Å; K133-M221 CarbonylContact O-C 3.56Å; K133-M221 WeakPolarHBondContact O-CA 3.21Å; F134-M221 HydrophobicContact CD1-CG 3.55Å; F134-M221 HydrophobicContact CD1-SD 4.46Å; F134-M221 HydrophobicContact CE1-CB 4.47Å; F134-M221 HydrophobicContact CE1-CG 3.47Å; F134-M221 VanDerWaalsContact CE1-CG 3.47Å; F134-M221 HydrophobicContact CE1-SD 3.86Å; F134-M221 HydrophobicContact CZ-CG 4.41Å; L219-M221 HydrophobicContact CB-CE 4.39Å; M221-I231 WeakPolarHBondContact O-CA 3.41Å; M221-K232 HydrophobicContact CB-CB 4.12Å; M221-K232 HydrophobicContact CE-CB 4.46Å; M221-K232 PolarHBondContact N-O 2.73Å; M221-K232 PolarHBondContact O-N 3.22Å; M221-K232 HydrophobicContact SD-CB 4.43Å; M221-A234 HydrophobicContact CE-CB 3.82Å
222F90.4Very high87.8Confident48 Ų4852.9 Ų52.921%0.21127%0.266CS..EExtended strand (participates in β ladder)trans-109.399.1177.9-52.5-87.3000107.7V132 K133 L135 E220 I231V132-F222 WeakPolarHBondContact CA-O 2.85Å; K133-F222 HydrophobicContact CB-CB 4.19Å; K133-F222 PolarHBondContact N-O 3.35Å; K133-F222 PolarHBondContact O-N 3.47Å; L135-F222 HydrophobicContact CB-CE2 3.96Å; E220-F222 HydrophobicContact CB-CE2 4.23Å; E220-F222 HydrophobicContact CB-CZ 4.25Å; F222-I231 HydrophobicContact CD1-CD1 4.2Å; F222-I231 HydrophobicContact CD1-CG1 3.95Å; F222-I231 HydrophobicContact CE1-CD1 4.09Å; F222-I231 HydrophobicContact CE1-CG1 4.24Å; F222-I231 HydrophobicContact CE1-CG2 4.38Å
223E86.4Confident87.8Confident56 Ų5655.4 Ų55.426%0.26228%0.282SS..EExtended strand (participates in β ladder)trans-96.3123.5179.7179.8171.7-171.300109.4V132 E229 H230 K232V132-E223 HydrophobicContact CG2-CB 4.15Å; V132-E223 HydrophobicContact CG2-CG 4.05Å; E223-E229 WeakPolarHBondContact O-CA 3.32Å; E223-H230 HydrophobicContact CB-CB 4.39Å; E223-H230 PolarHBondContact N-O 2.94Å; E223-H230 PolarHBondContact O-N 2.88Å; E223-K232 IonicContact OE2-NZ 3.96Å; E223-K232 PolarHBondContact OE2-NZ 2.93Å
224V80.7Confident87.9Confident76 Ų7655.3 Ų55.346%0.46128%0.281SS..EExtended strand (participates in β ladder)trans-97.5106.8177-176.30000108.7N131 R228 E229N131-V224 PolarHBondContact O-N 2.88Å; V224-R228 WeakPolarHBondContact CA-O 3.47Å; V224-E229 HydrophobicContact CG2-CG 4.49Å
225H74.7Confident87.8Confident94 Ų9458 Ų5844%0.43529%0.293SS..EExtended strand (participates in β ladder)trans-122.6121.5179.2-163.866.5000110.7G227 R228H225-G227 PolarHBondContact O-N 2.97Å; H225-G227 VanDerWaalsContact O-N 3.16Å; H225-R228 PolarHBondContact N-O 2.84Å; H225-R228 PolarHBondContact O-N 2.71Å
226H70.8Confident87.8Confident172 Ų17257.8 Ų57.880%0.79629%0.292SS*.THydrogen-bonded Turntrans49.638.7-178.7-62.6-60.5000114.7R228H226-R228 PolarHBondContact O-N 3.19Å
227G68.9Low87.8Confident75 Ų7558.9 Ų58.977%0.77330%0.297SS*.THydrogen-bonded Turntrans75.18-178.600000114.8H225H225-G227 PolarHBondContact O-N 2.97Å; H225-G227 VanDerWaalsContact O-N 3.16Å
228R72.2Confident87.9Confident142 Ų14259 Ų5954%0.53630%0.297SS..EExtended strand (participates in β ladder)trans-107.5142.6171.3-62-176-178.5-169.6-1.3109.9V224 H225 H226V224-R228 WeakPolarHBondContact CA-O 3.47Å; H225-R228 PolarHBondContact N-O 2.84Å; H225-R228 PolarHBondContact O-N 2.71Å; H226-R228 PolarHBondContact O-N 3.19Å
229E78.4Confident87.9Confident142 Ų14256.9 Ų56.966%0.66429%0.287SS*.EExtended strand (participates in β ladder)trans-94.6123.1175.9-64.6176.2177.500108.7E223 V224E223-E229 WeakPolarHBondContact O-CA 3.32Å; V224-E229 HydrophobicContact CG2-CG 4.49Å
230H85.4Confident87.9Confident54 Ų5457 Ų5725%0.2529%0.288CS..EExtended strand (participates in β ladder)trans-108.8129.2172.6-67.5-57.5000109.3E223 D347E223-H230 HydrophobicContact CB-CB 4.39Å; E223-H230 PolarHBondContact N-O 2.94Å; E223-H230 PolarHBondContact O-N 2.88Å; H230-D347 VanDerWaalsContact CA-OD2 3.29Å; H230-D347 WeakPolarHBondContact CA-OD2 3.48Å; H230-D347 IonicContact CE1-OD1 3.81Å; H230-D347 VanDerWaalsContact ND1-CG 3.32Å; H230-D347 IonicContact ND1-OD1 2.82Å; H230-D347 PolarHBondContact ND1-OD1 2.86Å; H230-D347 IonicContact ND1-OD2 3.87Å
231I89.6Confident88Confident50 Ų5053.1 Ų53.126%0.25627%0.27SS..EExtended strand (participates in β ladder)trans-106.8119.3-178.4-55.2177.1000109.2M221 F222 D344 D347M221-I231 WeakPolarHBondContact O-CA 3.41Å; F222-I231 HydrophobicContact CD1-CD1 4.2Å; F222-I231 HydrophobicContact CD1-CG1 3.95Å; F222-I231 HydrophobicContact CE1-CD1 4.09Å; F222-I231 HydrophobicContact CE1-CG1 4.24Å; F222-I231 HydrophobicContact CE1-CG2 4.38Å; I231-D344 HydrophobicContact CB-CB 4.37Å; I231-D344 PolarHBondContact O-N 3.45Å; I231-D347 PolarHBondContact N-OD2 2.82Å
232K92.5Very high87.9Confident43 Ų4352.9 Ų52.919%0.18727%0.269CS..EExtended strand (participates in β ladder)trans-112.6148.6171.7-65.3168.7-177.2160.20110M221 E223 I341 N342 E343M221-K232 HydrophobicContact CB-CB 4.12Å; M221-K232 HydrophobicContact CE-CB 4.46Å; M221-K232 PolarHBondContact N-O 2.73Å; M221-K232 PolarHBondContact O-N 3.22Å; M221-K232 HydrophobicContact SD-CB 4.43Å; E223-K232 IonicContact OE2-NZ 3.96Å; E223-K232 PolarHBondContact OE2-NZ 2.93Å; K232-I341 HydrophobicContact CD-CG2 4.2Å; K232-I341 HydrophobicContact CG-CG2 4.33Å; K232-N342 CarbonylContact C-O 3.47Å; K232-N342 VanDerWaalsContact CA-O 3.25Å; K232-N342 WeakPolarHBondContact CA-O 3.44Å; K232-E343 HydrophobicContact CG-CG 4.19Å
233T93.2Very high87.9Confident56 Ų5650.8 Ų50.834%0.34426%0.261SS..EExtended strand (participates in β ladder)trans-129.7147.7178.761.60000111.4G83 L219 E220 N342G83-T233 VanDerWaalsContact O-O 3.13Å; L219-T233 CarbonylContact O-C 3.46Å; L219-T233 WeakPolarHBondContact O-CA 3.5Å; E220-T233 HydrophobicContact CG-CG2 4.22Å; T233-N342 PolarHBondContact N-O 3.42Å; T233-N342 VanDerWaalsContact O-CB 3.31Å; T233-N342 WeakPolarHBondContact O-CB 3.25Å; T233-N342 PolarHBondContact O-ND2 2.79Å; T233-N342 WeakPolarHBondContact OG1-CB 3.27Å
234A95.4Very high88.1Confident2 Ų249 Ų492%0.01726%0.255CS..EExtended strand (participates in β ladder)trans-146.9146.4175.900000111.1V80 Y84 L219 M221V80-A234 HydrophobicContact CG1-CB 3.88Å; V80-A234 WeakPolarHBondContact O-CB 3.43Å; Y84-A234 WeakPolarHBondContact O-CB 3.36Å; L219-A234 HydrophobicContact CB-CB 4.4Å; L219-A234 PolarHBondContact N-O 3Å; L219-A234 PolarHBondContact O-N 2.68Å; M221-A234 HydrophobicContact CE-CB 3.82Å
235K95.6Very high88.3Confident62 Ų6247 Ų4727%0.2724%0.241SC..EExtended strand (participates in β ladder)trans-116.3130171-59178-171.4171.10109N85 G86 R168 L217N85-K235 CarbonylContact C-O 3.57Å; N85-K235 WeakPolarHBondContact CA-O 3.41Å; N85-K235 PolarHBondContact OD1-N 3.34Å; G86-K235 PolarHBondContact N-O 3.06Å; R168-K235 PolarHBondContact O-NZ 2.9Å; L217-K235 CarbonylContact O-C 3.55Å; L217-K235 WeakPolarHBondContact O-CA 3.44Å
236L97.8Very high88.3Confident0 Ų044.3 Ų44.30%023%0.226CC..EExtended strand (participates in β ladder)trans-115.4108.1171.3176.356.1000109.9L76 V77 V80 G86 T118 I122 T216 L217 L238L76-L236 HydrophobicContact CD2-CD1 4.4Å; V77-L236 HydrophobicContact CG2-CD2 4.33Å; V80-L236 HydrophobicContact CG1-CB 4.06Å; V80-L236 HydrophobicContact CG2-CB 4.25Å; V80-L236 HydrophobicContact CG2-CD1 4.18Å; G86-L236 WeakPolarHBondContact O-CA 3.5Å; T118-L236 HydrophobicContact CG2-CD2 3.45Å; T118-L236 VanDerWaalsContact CG2-CD2 3.45Å; I122-L236 HydrophobicContact CD1-CD2 4.05Å; T216-L236 VanDerWaalsContact CA-O 3.32Å; T216-L236 WeakPolarHBondContact CA-O 3.47Å; L217-L236 HydrophobicContact CB-CB 4.36Å; L217-L236 PolarHBondContact N-O 2.94Å; L217-L236 PolarHBondContact O-N 3.41Å; L236-L238 HydrophobicContact CD1-CD2 4.15Å; L236-L238 HydrophobicContact CD2-CD2 4.44Å; L236-L238 HydrophobicContact CG-CD2 4.17Å; L236-L238 HydrophobicContact CG-CG 4.26Å
237H97.8Very high88.3Confident27 Ų2737.6 Ų37.613%0.12520%0.196CC..EExtended strand (participates in β ladder)trans-90.4124.4174.3-60.7-58.9000110.5G86 T87 V88 T216 V239G86-H237 PolarHBondContact O-N 3.47Å; T87-H237 CarbonylContact C-O 3.37Å; T87-H237 WeakPolarHBondContact CA-O 3.34Å; T87-H237 HydrophobicContact CG2-CB 4.04Å; V88-H237 PolarHBondContact N-O 3.1Å; T216-H237 VanDerWaalsContact CG2-CE1 3.41Å; T216-H237 WeakPolarHBondContact CG2-CE1 3.49Å; T216-H237 WeakPolarHBondContact CG2-ND1 3.43Å; T216-H237 PolarHBondContact OG1-ND1 3.02Å; H237-V239 HydrophobicContact CB-CG2 4.14Å
238L98.1Very high88.3Confident4 Ų437.2 Ų37.22%0.02118%0.181CC..EExtended strand (participates in β ladder)trans-115.1105.8174.1-58.4171.3000107.6V88 M102 I114 V115 T118 F215 L236V88-L238 HydrophobicContact CB-CD2 4.12Å; V88-L238 HydrophobicContact CG2-CD2 4.19Å; M102-L238 HydrophobicContact CE-CB 3.87Å; M102-L238 HydrophobicContact CE-CD2 4.48Å; I114-L238 HydrophobicContact CG2-CD2 4.47Å; V115-L238 HydrophobicContact CB-CD1 4.26Å; V115-L238 HydrophobicContact CG1-CD1 4.07Å; V115-L238 HydrophobicContact CG2-CB 4.04Å; V115-L238 HydrophobicContact CG2-CD1 4Å; T118-L238 HydrophobicContact CG2-CD1 4.21Å; F215-L238 HydrophobicContact CB-CB 4.39Å; F215-L238 HydrophobicContact CD1-CD1 4.39Å; F215-L238 PolarHBondContact N-O 3.37Å; F215-L238 PolarHBondContact O-N 3.45Å; L236-L238 HydrophobicContact CD1-CD2 4.15Å; L236-L238 HydrophobicContact CD2-CD2 4.44Å; L236-L238 HydrophobicContact CG-CD2 4.17Å; L236-L238 HydrophobicContact CG-CG 4.26Å
239V97.1Very high88.1Confident0 Ų033.7 Ų33.70%017%0.17CC..EExtended strand (participates in β ladder)trans-115.8126.9-165.7-175.20000110.8T87 V88 F89 A90 S213 I214 H237 L241 L296T87-V239 HydrophobicContact CG2-CG2 4.48Å; V88-V239 PolarHBondContact O-N 3.01Å; F89-V239 WeakPolarHBondContact CA-O 3.34Å; F89-V239 HydrophobicContact CB-CB 3.63Å; F89-V239 HydrophobicContact CB-CG1 4.12Å; F89-V239 HydrophobicContact CB-CG2 4.3Å; A90-V239 PolarHBondContact N-O 3.22Å; S213-V239 WeakPolarHBondContact O-CA 3.43Å; I214-V239 HydrophobicContact CG1-CG1 4Å; I214-V239 HydrophobicContact CG1-CG2 4.11Å; I214-V239 HydrophobicContact CG2-CG2 4.15Å; H237-V239 HydrophobicContact CB-CG2 4.14Å; V239-L241 HydrophobicContact CG1-CD2 3.51Å; V239-L241 HydrophobicContact CG1-CG 3.96Å; V239-L296 HydrophobicContact CG2-CD2 4.23Å
240D95.5Very high87.5Confident4 Ų429.4 Ų29.42%0.02115%0.153CC..EExtended strand (participates in β ladder)trans-109.8104.4167.8-174.317.7000107.6K98 S99 M102 R197 H212 S213K98-D240 WeakPolarHBondContact CB-OD1 3.42Å; S99-D240 WeakPolarHBondContact CB-OD2 3.3Å; S99-D240 PolarHBondContact OG-OD2 3.44Å; M102-D240 HydrophobicContact CG-CB 4.4Å; R197-D240 IonicContact NH1-OD2 2.84Å; H212-D240 WeakPolarHBondContact CA-O 3.48Å; S213-D240 PolarHBondContact N-O 2.79Å; S213-D240 PolarHBondContact O-N 2.94Å
241L94.5Very high86.5Confident2 Ų237.6 Ų37.61%0.0118%0.182CC..PPolyproline II helixtrans-76.9157.6-177.4-62.5175.5000111.2F89 A90 Y91 K98 H212 V239 L270 L292F89-L241 HydrophobicContact CD2-CD1 3.81Å; F89-L241 HydrophobicContact CE2-CD1 4.46Å; A90-L241 WeakPolarHBondContact O-CB 3.27Å; A90-L241 WeakPolarHBondContact O-CG 3.47Å; A90-L241 PolarHBondContact O-N 2.84Å; Y91-L241 HydrophobicContact CD2-CD1 3.81Å; Y91-L241 HydrophobicContact CG-CD1 4.48Å; K98-L241 WeakPolarHBondContact CE-O 3.43Å; H212-L241 HydrophobicContact CB-CD2 4.48Å; H212-L241 WeakPolarHBondContact ND1-CA 3.38Å; H212-L241 WeakPolarHBondContact ND1-CD2 3.38Å; V239-L241 HydrophobicContact CG1-CD2 3.51Å; V239-L241 HydrophobicContact CG1-CG 3.96Å; L241-L270 HydrophobicContact CD1-CD2 4.17Å; L241-L292 HydrophobicContact CD2-CD1 3.91Å; L241-L292 HydrophobicContact CD2-CD2 3.85Å; L241-L292 HydrophobicContact CD2-CG 4.48Å
242A91.3Very high85.4Confident1 Ų135.8 Ų35.81%0.00817%0.174CC..PPolyproline II helixtrans-59.5160.6170.600000111.7S209 H212 S244 I263S209-A242 CarbonylContact O-C 3.6Å; S209-A242 VanDerWaalsContact O-CA 3.32Å; S209-A242 WeakPolarHBondContact O-CA 3.42Å; H212-A242 WeakPolarHBondContact CE1-CB 3.5Å; H212-A242 PolarHBondContact CE1-N 3.06Å; H212-A242 PolarHBondContact ND1-N 2.91Å; A242-S244 PolarHBondContact O-N 3.31Å; A242-I263 HydrophobicContact CB-CG2 4.25Å
243G90.2Very high84.2Confident5 Ų539.4 Ų39.45%0.05220%0.2CC..PPolyproline II helixtrans-54.7131172.700000112.4S209 E245 L267S209-G243 PolarHBondContact O-N 2.9Å; G243-E245 VanDerWaalsContact C-N 3.32Å; G243-E245 WeakPolarHBondContact CA-OE2 3.4Å; G243-L267 VanDerWaalsContact O-CD1 3.24Å; G243-L267 WeakPolarHBondContact O-CD1 3.48Å
244S89.9Confident83.1Confident19 Ų1938 Ų3813%0.13320%0.196CC..  trans-86.52.2178690000114.6Y91 G92 Q93 A242Y91-S244 WeakPolarHBondContact OH-CB 3.4Å; G92-S244 WeakPolarHBondContact CA-OG 3.5Å; G92-S244 PolarHBondContact O-N 2.77Å; G92-S244 VanDerWaalsContact O-N 3.14Å; G92-S244 PolarHBondContact O-OG 2.74Å; Q93-S244 PolarHBondContact N-OG 3.3Å; A242-S244 PolarHBondContact O-N 3.31Å
245E86.1Confident81.8Confident33 Ų3343.4 Ų43.415%0.15423%0.225CC..  trans-67.4151.2-177.666.8-80.3-170.900113.5Q93 T94 G243 E321Q93-E245 VanDerWaalsContact CA-OE2 3.31Å; Q93-E245 WeakPolarHBondContact CA-OE2 3.3Å; Q93-E245 HydrophobicContact CB-CB 4.11Å; T94-E245 WeakPolarHBondContact CB-OE1 3.41Å; T94-E245 PolarHBondContact N-OE2 3.44Å; T94-E245 VanDerWaalsContact OG1-CD 3.3Å; T94-E245 PolarHBondContact OG1-OE1 2.84Å; T94-E245 PolarHBondContact OG1-OE2 3.45Å; G243-E245 VanDerWaalsContact C-N 3.32Å; G243-E245 WeakPolarHBondContact CA-OE2 3.4Å; E245-E321 WeakPolarHBondContact CA-OE2 3.11Å; E245-E321 HydrophobicContact CB-CG 4.31Å
246R74.9Confident80.5Confident37 Ų3746.2 Ų46.214%0.1423%0.234CC..  trans-73.9144.7-179.7-60.3-177.4-174.6-156-1.7112S248 K249 E321 E549 E553 D556R246-S248 PolarHBondContact O-N 3.23Å; R246-K249 WeakPolarHBondContact O-CB 3.33Å; R246-K249 PolarHBondContact O-N 2.8Å; R246-E321 PolarHBondContact N-OE1 2.95Å; R246-E549 PolarHBondContact NH1-O 2.94Å; R246-E549 PolarHBondContact NH2-O 3.15Å; R246-E553 VanDerWaalsContact NH1-N 3.17Å; R246-D556 WeakPolarHBondContact CD-OD2 3.39Å
247Q69.3Low79.1Confident32 Ų3246.7 Ų46.715%0.1524%0.236CC..Hα-helixtrans-66-22.4-178.6-61.9-59.2-24.400113.5K249 T250 A260 N264Q247-K249 PolarHBondContact O-N 3.03Å; Q247-T250 PolarHBondContact O-N 3.35Å; Q247-T250 PolarHBondContact O-OG1 2.91Å; Q247-T250 PolarHBondContact OE1-OG1 3.41Å; Q247-T250 VanDerWaalsContact OE1-OG1 3.06Å; Q247-A260 HydrophobicContact CB-CB 4.43Å; Q247-A260 HydrophobicContact CG-CB 3.73Å; Q247-A260 PolarHBondContact NE2-O 3.48Å; Q247-N264 WeakPolarHBondContact CG-ND2 3.34Å; Q247-N264 PolarHBondContact NE2-OD1 3.14Å
248S68.6Low77.9Confident66 Ų6649.7 Ų49.746%0.46225%0.249SC..Hα-helixtrans-56.7-27.8171.642.50000112.5R246 D556R246-S248 PolarHBondContact O-N 3.23Å; S248-D556 VanDerWaalsContact CB-OD1 3.23Å; S248-D556 WeakPolarHBondContact CB-OD1 3.48Å; S248-D556 PolarHBondContact OG-OD1 3.35Å; S248-D556 PolarHBondContact OG-OD2 3.24Å; S248-D556 VanDerWaalsContact OG-OD2 3.08Å
249K68Low76.6Confident69 Ų6950.5 Ų50.530%0.325%0.253SS..Hα-helixtrans-73.9-31.1173.6-67.2-165.5174.3-165.80113.8R246 Q247 R251 Y317 E321R246-K249 WeakPolarHBondContact O-CB 3.33Å; R246-K249 PolarHBondContact O-N 2.8Å; Q247-K249 PolarHBondContact O-N 3.03Å; K249-R251 VanDerWaalsContact C-N 3.33Å; K249-R251 PolarHBondContact O-N 2.98Å; K249-Y317 PolarHBondContact NZ-O 3.04Å; K249-E321 HydrophobicContact CD-CG 4.32Å; K249-E321 WeakPolarHBondContact CD-OE1 3.34Å; K249-E321 WeakPolarHBondContact CE-OE1 3.17Å; K249-E321 IonicContact NZ-OE1 3.26Å
250T66.9Low75.3Confident52 Ų5250.5 Ų50.532%0.31925%0.253SS..Hα-helixtrans-79.8-13.8-17266.80000113.7Q247 A252Q247-T250 PolarHBondContact O-N 3.35Å; Q247-T250 PolarHBondContact O-OG1 2.91Å; Q247-T250 PolarHBondContact OE1-OG1 3.41Å; Q247-T250 VanDerWaalsContact OE1-OG1 3.06Å; T250-A252 PolarHBondContact O-N 2.88Å
251R65.2Low74.3Confident226 Ų22652.7 Ų52.785%0.85327%0.266SS*.THydrogen-bonded Turntrans47.730.9-177.5-63-174.7177.7-177.70.3113.6K249K249-R251 VanDerWaalsContact C-N 3.33Å; K249-R251 PolarHBondContact O-N 2.98Å
252A65.7Low73.5Confident12 Ų1258.1 Ų58.110%0.09929%0.29CS..  trans-73.2144.3-177.800000112.6T250 R256T250-A252 PolarHBondContact O-N 2.88Å; A252-R256 HydrophobicContact CB-CB 3.88Å
253V67Low72.6Confident119 Ų11958.4 Ų58.472%0.72129%0.291SS*.  trans-127.9155.8177.6-170.90000109.3
254G69.9Low71.9Confident26 Ų2659.8 Ų59.827%0.26830%0.297SS..THydrogen-bonded Turntrans73.4-136.9173.500000113.4R256 L257G254-R256 VanDerWaalsContact C-N 3.28Å; G254-R256 PolarHBondContact O-N 3.25Å; G254-L257 VanDerWaalsContact O-CB 3.27Å; G254-L257 WeakPolarHBondContact O-CB 3.4Å; G254-L257 PolarHBondContact O-N 3.27Å
255D68.3Low71.7Confident116 Ų11662.8 Ų62.862%0.6231%0.311SS*.Hα-helixtrans-67.1-28.5-178.6-67.1-40.5000113.2L257 K258 E259D255-L257 PolarHBondContact O-N 3.09Å; D255-K258 PolarHBondContact O-N 2.65Å; D255-K258 VanDerWaalsContact O-N 3.08Å; D255-K258 IonicContact OD1-NZ 3.95Å; D255-K258 PolarHBondContact OD1-NZ 2.63Å; D255-E259 PolarHBondContact O-N 3.01Å
256R68.1Low71.8Confident120 Ų12061.3 Ų61.345%0.45331%0.305SS..Hα-helixtrans-60-27.6171.3-71.7-171.6178.5164.30.4112.4N205 A252 G254 A260N205-R256 PolarHBondContact ND2-NH2 3.43Å; A252-R256 HydrophobicContact CB-CB 3.88Å; G254-R256 VanDerWaalsContact C-N 3.28Å; G254-R256 PolarHBondContact O-N 3.25Å; R256-A260 WeakPolarHBondContact O-CB 3.49Å; R256-A260 PolarHBondContact O-N 2.74Å
257L69.1Low72.5Confident11 Ų1160.1 Ų60.16%0.05830%0.301CS..Hα-helixtrans-72.6-43174.5-177.569.4000111.4G254 D255 E259 A260 T261 K563G254-L257 VanDerWaalsContact O-CB 3.27Å; G254-L257 WeakPolarHBondContact O-CB 3.4Å; G254-L257 PolarHBondContact O-N 3.27Å; D255-L257 PolarHBondContact O-N 3.09Å; L257-E259 VanDerWaalsContact C-N 3.32Å; L257-E259 PolarHBondContact O-N 3.31Å; L257-A260 WeakPolarHBondContact O-CB 3.47Å; L257-A260 PolarHBondContact O-N 2.79Å; L257-T261 PolarHBondContact O-N 2.94Å; L257-T261 PolarHBondContact O-OG1 3.36Å; L257-K563 HydrophobicContact CD1-CD 4.48Å; L257-K563 HydrophobicContact CD2-CB 3.58Å; L257-K563 HydrophobicContact CD2-CD 3.45Å; L257-K563 VanDerWaalsContact CD2-CD 3.45Å; L257-K563 HydrophobicContact CD2-CG 4.16Å
258K72Confident73.3Confident90 Ų9060.3 Ų60.339%0.39131%0.306SS..Hα-helixtrans-63.1-41.2177.3-66176.8-173.9158.60111.3D255 K262D255-K258 PolarHBondContact O-N 2.65Å; D255-K258 VanDerWaalsContact O-N 3.08Å; D255-K258 IonicContact OD1-NZ 3.95Å; D255-K258 PolarHBondContact OD1-NZ 2.63Å; K258-K262 WeakPolarHBondContact O-CG 3.32Å; K258-K262 PolarHBondContact O-N 2.88Å
259E70.9Confident74.4Confident21 Ų2157.3 Ų57.310%0.09829%0.285CS..Hα-helixtrans-59.5-53172166.7-175178.700111.1Y144 I145 R210 D255 L257 T261 K262 I263Y144-E259 WeakPolarHBondContact CE2-OE1 3.47Å; Y144-E259 PolarHBondContact OH-OE1 3.37Å; I145-E259 HydrophobicContact CD1-CB 3.9Å; I145-E259 HydrophobicContact CD1-CG 3.6Å; I145-E259 HydrophobicContact CG1-CG 4Å; R210-E259 VanDerWaalsContact CD-OE1 3.24Å; R210-E259 WeakPolarHBondContact CD-OE1 3.42Å; R210-E259 IonicContact CZ-OE1 3.84Å; R210-E259 IonicContact NH1-OE1 2.73Å; R210-E259 PolarHBondContact NH1-OE1 2.63Å; R210-E259 IonicContact NH1-OE2 3.71Å; R210-E259 PolarHBondContact NH1-OE2 2.87Å; R210-E259 VanDerWaalsContact NH1-OE2 3.07Å; D255-E259 PolarHBondContact O-N 3.01Å; L257-E259 VanDerWaalsContact C-N 3.32Å; L257-E259 PolarHBondContact O-N 3.31Å; E259-T261 VanDerWaalsContact C-N 3.31Å; E259-T261 PolarHBondContact O-N 2.88Å; E259-K262 CarbonylContact O-C 3.53Å; E259-K262 PolarHBondContact O-N 3.2Å; E259-I263 HydrophobicContact CG-CD1 3.54Å; E259-I263 HydrophobicContact CG-CG1 4.33Å; E259-I263 WeakPolarHBondContact O-CG1 3.26Å; E259-I263 PolarHBondContact O-N 2.85Å
260A69.4Low75.5Confident0 Ų054 Ų540%027%0.271CS..Hα-helixtrans-52.2-44.6176.600000113.2Q247 R256 L257 K262 I263 N264Q247-A260 HydrophobicContact CB-CB 4.43Å; Q247-A260 HydrophobicContact CG-CB 3.73Å; Q247-A260 PolarHBondContact NE2-O 3.48Å; R256-A260 WeakPolarHBondContact O-CB 3.49Å; R256-A260 PolarHBondContact O-N 2.74Å; L257-A260 WeakPolarHBondContact O-CB 3.47Å; L257-A260 PolarHBondContact O-N 2.79Å; A260-K262 VanDerWaalsContact C-N 3.34Å; A260-K262 PolarHBondContact O-N 3.35Å; A260-I263 PolarHBondContact O-N 3.37Å; A260-N264 PolarHBondContact O-N 3.39Å
261T75.2Confident76.7Confident50 Ų5051.9 Ų51.931%0.30726%0.259SS..Hα-helixtrans-61.1-42175.5-51.10000111.8L257 E259 L265 T560L257-T261 PolarHBondContact O-N 2.94Å; L257-T261 PolarHBondContact O-OG1 3.36Å; E259-T261 VanDerWaalsContact C-N 3.31Å; E259-T261 PolarHBondContact O-N 2.88Å; T261-L265 PolarHBondContact O-N 3.18Å; T261-T560 HydrophobicContact CG2-CG2 4.12Å; T261-T560 WeakPolarHBondContact OG1-CG2 3.45Å
262K76.7Confident77.9Confident115 Ų11545.4 Ų45.450%0.524%0.241SC..Hα-helixtrans-74-30179.9-72.9-174.9176.3-174.60113.5I145 K258 E259 A260 L265I145-K262 HydrophobicContact CG2-CB 3.73Å; I145-K262 HydrophobicContact CG2-CD 3.24Å; I145-K262 HydrophobicContact CG2-CG 4.14Å; K258-K262 WeakPolarHBondContact O-CG 3.32Å; K258-K262 PolarHBondContact O-N 2.88Å; E259-K262 CarbonylContact O-C 3.53Å; E259-K262 PolarHBondContact O-N 3.2Å; A260-K262 VanDerWaalsContact C-N 3.34Å; A260-K262 PolarHBondContact O-N 3.35Å; K262-L265 WeakPolarHBondContact O-CB 3.45Å; K262-L265 PolarHBondContact O-N 3.18Å
263I72.7Confident79.2Confident7 Ų744.8 Ų44.84%0.03624%0.236CC..Hα-helixtrans-65.4-47.6173.7-67.2156.7000109.7R210 A242 E259 A260 L265 S266R210-I263 HydrophobicContact CB-CD1 3.54Å; R210-I263 HydrophobicContact CB-CG1 4.34Å; R210-I263 HydrophobicContact CG-CD1 3.71Å; A242-I263 HydrophobicContact CB-CG2 4.25Å; E259-I263 HydrophobicContact CG-CD1 3.54Å; E259-I263 HydrophobicContact CG-CG1 4.33Å; E259-I263 WeakPolarHBondContact O-CG1 3.26Å; E259-I263 PolarHBondContact O-N 2.85Å; A260-I263 PolarHBondContact O-N 3.37Å; I263-L265 PolarHBondContact O-N 3.26Å; I263-S266 PolarHBondContact O-N 3.05Å; I263-S266 PolarHBondContact O-OG 3.5Å
264N76.9Confident80.4Confident34 Ų3439.1 Ų39.118%0.18220%0.202CC..Hα-helixtrans-64.6-28.1179.6-76.223000112.7Q247 A260 S266 L267 S268Q247-N264 WeakPolarHBondContact CG-ND2 3.34Å; Q247-N264 PolarHBondContact NE2-OD1 3.14Å; A260-N264 PolarHBondContact O-N 3.39Å; N264-S266 VanDerWaalsContact C-N 3.29Å; N264-S266 PolarHBondContact O-N 3.49Å; N264-L267 PolarHBondContact O-N 3.37Å; N264-S268 VanDerWaalsContact O-CB 3.3Å; N264-S268 WeakPolarHBondContact O-CB 3.49Å; N264-S268 PolarHBondContact O-N 3.22Å; N264-S268 PolarHBondContact O-OG 2.87Å; N264-S268 VanDerWaalsContact O-OG 3.08Å
265L84.2Confident81.3Confident82 Ų8239.2 Ų39.243%0.42920%0.199SC..Hα-helixtrans-52.3-47175.1177.363.1000112E146 T261 K262 I263 A269E146-L265 HydrophobicContact CG-CD2 4.33Å; T261-L265 PolarHBondContact O-N 3.18Å; K262-L265 WeakPolarHBondContact O-CB 3.45Å; K262-L265 PolarHBondContact O-N 3.18Å; I263-L265 PolarHBondContact O-N 3.26Å; L265-A269 WeakPolarHBondContact O-CB 3.44Å; L265-A269 PolarHBondContact O-N 3Å
266S89.6Confident82.4Confident2 Ų234.3 Ų34.31%0.01417%0.174CC..Hα-helixtrans-63.5-42.4-178.5650000113.5E146 H212 I263 N264 L270E146-S266 WeakPolarHBondContact OE1-CB 3.41Å; H212-S266 PolarHBondContact NE2-OG 3.3Å; I263-S266 PolarHBondContact O-N 3.05Å; I263-S266 PolarHBondContact O-OG 3.5Å; N264-S266 VanDerWaalsContact C-N 3.29Å; N264-S266 PolarHBondContact O-N 3.49Å; S266-L270 WeakPolarHBondContact O-CB 3.4Å; S266-L270 PolarHBondContact O-N 3.37Å
267L88.6Confident83.5Confident12 Ų1230.5 Ų30.56%0.06316%0.162CC..Hα-helixtrans-76-38179.8-68.3179.6000112.2Y91 G243 N264 L270 G271Y91-L267 HydrophobicContact CD2-CD2 4.44Å; Y91-L267 HydrophobicContact CE2-CD2 4.07Å; G243-L267 VanDerWaalsContact O-CD1 3.24Å; G243-L267 WeakPolarHBondContact O-CD1 3.48Å; N264-L267 PolarHBondContact O-N 3.37Å; L267-L270 WeakPolarHBondContact O-CB 3.43Å; L267-L270 PolarHBondContact O-N 2.99Å; L267-G271 PolarHBondContact O-N 3.12Å
268S87Confident84.5Confident37 Ų3731.9 Ų31.926%0.25917%0.171SC..Hα-helixtrans-64.7-42.7173.1-64.30000111.2N264 L270 G271 N272 Y557N264-S268 VanDerWaalsContact O-CB 3.3Å; N264-S268 WeakPolarHBondContact O-CB 3.49Å; N264-S268 PolarHBondContact O-N 3.22Å; N264-S268 PolarHBondContact O-OG 2.87Å; N264-S268 VanDerWaalsContact O-OG 3.08Å; S268-L270 VanDerWaalsContact C-N 3.33Å; S268-L270 PolarHBondContact O-N 2.92Å; S268-G271 PolarHBondContact O-N 3.34Å; S268-G271 VanDerWaalsContact O-N 3.15Å; S268-N272 PolarHBondContact O-N 3.31Å; S268-Y557 PolarHBondContact OG-OH 3.41Å
269A90.2Very high85.2Confident2 Ų232.6 Ų32.62%0.01718%0.179CC..Hα-helixtrans-59.7-43.2173.400000111.5L265 G271 N272 V273 D289 T293L265-A269 WeakPolarHBondContact O-CB 3.44Å; L265-A269 PolarHBondContact O-N 3Å; A269-G271 VanDerWaalsContact C-N 3.33Å; A269-G271 PolarHBondContact O-N 3.37Å; A269-N272 PolarHBondContact O-N 3.3Å; A269-V273 WeakPolarHBondContact O-CG2 3.24Å; A269-V273 PolarHBondContact O-N 3.32Å; A269-D289 HydrophobicContact CB-CB 3.87Å; A269-T293 HydrophobicContact CB-CG2 4.31Å
270L92.9Very high85.6Confident1 Ų134.6 Ų34.61%0.00521%0.205CC..Hα-helixtrans-58.8-45.1174-165.468.2000111.1L241 S266 L267 S268 N272 V273 I274 L292 T293 L296 L300 Y328L241-L270 HydrophobicContact CD1-CD2 4.17Å; S266-L270 WeakPolarHBondContact O-CB 3.4Å; S266-L270 PolarHBondContact O-N 3.37Å; L267-L270 WeakPolarHBondContact O-CB 3.43Å; L267-L270 PolarHBondContact O-N 2.99Å; S268-L270 VanDerWaalsContact C-N 3.33Å; S268-L270 PolarHBondContact O-N 2.92Å; L270-N272 VanDerWaalsContact C-N 3.33Å; L270-N272 PolarHBondContact O-N 3.44Å; L270-V273 PolarHBondContact O-N 2.78Å; L270-I274 WeakPolarHBondContact O-CG1 3.43Å; L270-I274 PolarHBondContact O-N 2.88Å; L270-L292 HydrophobicContact CD2-CD2 4.39Å; L270-T293 HydrophobicContact CB-CG2 4.04Å; L270-T293 HydrophobicContact CD1-CG2 3.72Å; L270-L296 HydrophobicContact CD1-CD1 4.5Å; L270-L300 HydrophobicContact CD1-CD1 3.4Å; L270-L300 VanDerWaalsContact CD1-CD1 3.4Å; L270-L300 HydrophobicContact CG-CD1 4.45Å; L270-Y328 WeakPolarHBondContact CD2-OH 3.23Å; L270-Y328 WeakPolarHBondContact CG-OH 3.42Å
271G90.6Very high86.1Confident6 Ų643.5 Ų43.56%0.06224%0.244CC..Hα-helixtrans-60.6-37.217500000114.3L267 S268 A269 S275L267-G271 PolarHBondContact O-N 3.12Å; S268-G271 PolarHBondContact O-N 3.34Å; S268-G271 VanDerWaalsContact O-N 3.15Å; A269-G271 VanDerWaalsContact C-N 3.33Å; A269-G271 PolarHBondContact O-N 3.37Å; G271-S275 PolarHBondContact O-N 3.27Å; G271-S275 PolarHBondContact O-OG 2.9Å
272N90.6Very high86.3Confident90 Ų9043.4 Ų43.448%0.48125%0.245SC..Hα-helixtrans-67.8-42.9175.4-69.9-14.3000111.7S268 A269 L270 I274 S275 A276 P286S268-N272 PolarHBondContact O-N 3.31Å; A269-N272 PolarHBondContact O-N 3.3Å; L270-N272 VanDerWaalsContact C-N 3.33Å; L270-N272 PolarHBondContact O-N 3.44Å; N272-I274 PolarHBondContact O-N 3.48Å; N272-S275 PolarHBondContact O-N 3.45Å; N272-A276 WeakPolarHBondContact O-CB 3.45Å; N272-A276 PolarHBondContact O-N 3.24Å; N272-P286 HydrophobicContact CB-CG 4.34Å
273V93.1Very high86.7Confident0 Ų045 Ų450%027%0.265CS..Hα-helixtrans-59.4-46174.7167.50000110.9A269 L270 S275 A276 L277 I285 P286 Y287 T293A269-V273 WeakPolarHBondContact O-CG2 3.24Å; A269-V273 PolarHBondContact O-N 3.32Å; L270-V273 PolarHBondContact O-N 2.78Å; V273-S275 PolarHBondContact O-N 2.81Å; V273-A276 PolarHBondContact O-N 2.91Å; V273-L277 HydrophobicContact CG1-CD1 3.76Å; V273-L277 HydrophobicContact CG1-CG 4.39Å; V273-L277 WeakPolarHBondContact O-CB 3.5Å; V273-L277 VanDerWaalsContact O-CG 3.26Å; V273-L277 WeakPolarHBondContact O-CG 3.22Å; V273-L277 PolarHBondContact O-N 3.37Å; V273-I285 HydrophobicContact CB-CG2 4.37Å; V273-I285 HydrophobicContact CG1-CG2 3.83Å; V273-I285 HydrophobicContact CG2-CG2 4.27Å; V273-P286 HydrophobicContact CG2-CG 4.06Å; V273-Y287 HydrophobicContact CG1-CD1 3.85Å; V273-Y287 HydrophobicContact CG1-CE1 3.52Å; V273-Y287 HydrophobicContact CG2-CD1 4.23Å; V273-T293 HydrophobicContact CG2-CG2 3.94Å
274I92.3Very high87.5Confident0 Ų051.2 Ų51.20%029%0.294CS..Hα-helixtrans-60-46.7177.1-66.5-174.4000111.1L270 N272 A276 L277 V278 Y328 R331 A332 I335L270-I274 WeakPolarHBondContact O-CG1 3.43Å; L270-I274 PolarHBondContact O-N 2.88Å; N272-I274 PolarHBondContact O-N 3.48Å; I274-A276 PolarHBondContact O-N 2.98Å; I274-L277 PolarHBondContact O-N 3.5Å; I274-V278 HydrophobicContact CG2-CG2 4.25Å; I274-V278 VanDerWaalsContact O-CG2 3.23Å; I274-V278 WeakPolarHBondContact O-CG2 3.41Å; I274-V278 PolarHBondContact O-N 2.9Å; I274-Y328 HydrophobicContact CD1-CD1 4.27Å; I274-Y328 HydrophobicContact CD1-CE1 3.39Å; I274-Y328 HydrophobicContact CD1-CE2 4.23Å; I274-Y328 VanDerWaalsContact CD1-OH 3.23Å; I274-Y328 WeakPolarHBondContact CD1-OH 3.23Å; I274-R331 HydrophobicContact CG2-CB 3.86Å; I274-A332 HydrophobicContact CD1-CB 4.07Å; I274-I335 HydrophobicContact CB-CD1 4.13Å; I274-I335 HydrophobicContact CD1-CD1 4.12Å; I274-I335 HydrophobicContact CG1-CD1 3.66Å; I274-I335 HydrophobicContact CG2-CD1 3.89Å; I274-I335 HydrophobicContact CG2-CG1 4.22Å
275S89.4Confident88.2Confident28 Ų2851.2 Ų51.220%0.19629%0.293CS..Hα-helixtrans-62.5-44.1-179.1-52.80000111.5G271 N272 V273 L277 V278 D279 R331G271-S275 PolarHBondContact O-N 3.27Å; G271-S275 PolarHBondContact O-OG 2.9Å; N272-S275 PolarHBondContact O-N 3.45Å; V273-S275 PolarHBondContact O-N 2.81Å; S275-L277 VanDerWaalsContact C-N 3.35Å; S275-L277 PolarHBondContact O-N 2.88Å; S275-V278 PolarHBondContact O-N 3.33Å; S275-D279 WeakPolarHBondContact O-CB 3.29Å; S275-D279 PolarHBondContact O-N 3.28Å; S275-R331 PolarHBondContact OG-NH1 2.76Å
276A91.2Very high88.7Confident13 Ų1348.4 Ų48.411%0.10728%0.28CS..Hα-helixtrans-61.7-40.4176.500000112.5N272 V273 I274 G280 S282 I285N272-A276 WeakPolarHBondContact O-CB 3.45Å; N272-A276 PolarHBondContact O-N 3.24Å; V273-A276 PolarHBondContact O-N 2.91Å; I274-A276 PolarHBondContact O-N 2.98Å; A276-G280 PolarHBondContact O-N 3.5Å; A276-S282 WeakPolarHBondContact CA-OG 3.43Å; A276-S282 WeakPolarHBondContact CB-OG 3.48Å; A276-S282 PolarHBondContact O-OG 3.19Å; A276-I285 HydrophobicContact CB-CD1 3.67Å
277L91.6Very high88.9Confident39 Ų3949.7 Ų49.720%0.20429%0.285CS..Hα-helixtrans-69.2-36.7178.2-74.7170.5000113.1V273 I274 S275 I285 L300 I335V273-L277 HydrophobicContact CG1-CD1 3.76Å; V273-L277 HydrophobicContact CG1-CG 4.39Å; V273-L277 WeakPolarHBondContact O-CB 3.5Å; V273-L277 VanDerWaalsContact O-CG 3.26Å; V273-L277 WeakPolarHBondContact O-CG 3.22Å; V273-L277 PolarHBondContact O-N 3.37Å; I274-L277 PolarHBondContact O-N 3.5Å; S275-L277 VanDerWaalsContact C-N 3.35Å; S275-L277 PolarHBondContact O-N 2.88Å; L277-I285 HydrophobicContact CD2-CD1 4.01Å; L277-I285 HydrophobicContact CD2-CG1 4.02Å; L277-I285 HydrophobicContact CD2-CG2 4.34Å; L277-I285 HydrophobicContact CG-CD1 4.29Å; L277-I285 HydrophobicContact CG-CG2 4.19Å; L277-L300 HydrophobicContact CD1-CB 4.17Å; L277-L300 WeakPolarHBondContact CD1-O 3.21Å; L277-I335 HydrophobicContact CB-CG1 4.43Å; L277-I335 HydrophobicContact CD1-CG2 4.09Å
278V89.3Confident89.1Confident40 Ų4057.6 Ų57.624%0.24231%0.314CS..Hα-helixtrans-76.8-44.1-178.41730000111.4I274 S275 G280 R331 N334 I335I274-V278 HydrophobicContact CG2-CG2 4.25Å; I274-V278 VanDerWaalsContact O-CG2 3.23Å; I274-V278 WeakPolarHBondContact O-CG2 3.41Å; I274-V278 PolarHBondContact O-N 2.9Å; S275-V278 PolarHBondContact O-N 3.33Å; V278-G280 PolarHBondContact O-N 3.49Å; V278-R331 VanDerWaalsContact CG2-O 3.23Å; V278-R331 WeakPolarHBondContact CG2-O 3.42Å; V278-N334 HydrophobicContact CG1-CB 3.83Å; V278-N334 HydrophobicContact CG2-CB 3.98Å; V278-I335 HydrophobicContact CG2-CG1 3.96Å
279D86.2Confident89.2Confident106 Ų10659.9 Ų59.957%0.56732%0.323SS*.Hα-helixtrans-64.1-33.4-179.2-76.3-14.7000111.7S275 K281S275-D279 WeakPolarHBondContact O-CB 3.29Å; S275-D279 PolarHBondContact O-N 3.28Å; D279-K281 PolarHBondContact O-N 3.31Å
280G80.3Confident89.4Confident62 Ų6259.9 Ų59.964%0.63932%0.323SS*.  trans63-1.7-179.800000114.9A276 V278A276-G280 PolarHBondContact O-N 3.5Å; V278-G280 PolarHBondContact O-N 3.49Å
281K80.5Confident89.4Confident187 Ų18763.3 Ų63.381%0.81334%0.338SS*.  trans-78.5-31.8178.3-66.5174.4-173.41710112.1D279D279-K281 PolarHBondContact O-N 3.31Å
282S79.1Confident89.6Confident48 Ų4863 Ų6334%0.33634%0.335SS..  trans-81.8122.8178.651.80000110.5A276A276-S282 WeakPolarHBondContact CA-OG 3.43Å; A276-S282 WeakPolarHBondContact CB-OG 3.48Å; A276-S282 PolarHBondContact O-OG 3.19Å
283T84.1Confident89.8Confident150 Ų15058.8 Ų58.892%0.9231%0.312SS*.SBendtrans-73.2-32.1173.451.30000112.4
284H89.9Confident89.9Confident137 Ų13760.4 Ų60.463%0.63432%0.318SS*.SBendtrans-100.7123.3179.2179.2-95.9000110.9
285I92.3Very high90Very high34 Ų3461.8 Ų61.817%0.17433%0.325CS..  trans-100.8125.9175.4-51.6-59.3000109V273 A276 L277 Y287V273-I285 HydrophobicContact CB-CG2 4.37Å; V273-I285 HydrophobicContact CG1-CG2 3.83Å; V273-I285 HydrophobicContact CG2-CG2 4.27Å; A276-I285 HydrophobicContact CB-CD1 3.67Å; L277-I285 HydrophobicContact CD2-CD1 4.01Å; L277-I285 HydrophobicContact CD2-CG1 4.02Å; L277-I285 HydrophobicContact CD2-CG2 4.34Å; L277-I285 HydrophobicContact CG-CD1 4.29Å; L277-I285 HydrophobicContact CG-CG2 4.19Å; I285-Y287 HydrophobicContact CB-CD2 3.83Å; I285-Y287 HydrophobicContact CB-CE2 3.47Å; I285-Y287 VanDerWaalsContact CB-CE2 3.47Å; I285-Y287 HydrophobicContact CG1-CE2 4.21Å; I285-Y287 HydrophobicContact CG2-CD1 4.34Å; I285-Y287 HydrophobicContact CG2-CD2 3.71Å; I285-Y287 HydrophobicContact CG2-CE1 4.01Å; I285-Y287 HydrophobicContact CG2-CE2 3.32Å; I285-Y287 HydrophobicContact CG2-CG 4.21Å; I285-Y287 VanDerWaalsContact CG2-CZ 3.49Å; I285-Y287 PolarHBondContact O-N 3.35Å
286P93Very high90.2Very high22 Ų2260.6 Ų60.614%0.14332%0.317CS..  trans-79.950.6-170.733.8-37.6000113.9N272 V273 R288 D289N272-P286 HydrophobicContact CB-CG 4.34Å; V273-P286 HydrophobicContact CG2-CG 4.06Å; P286-R288 PolarHBondContact O-N 3.42Å; P286-R288 VanDerWaalsContact O-N 3.09Å; P286-D289 WeakPolarHBondContact CB-OD2 3.26Å; P286-D289 PolarHBondContact O-N 3.14Å
287Y94.2Very high90.3Very high30 Ų3063.2 Ų63.212%0.11833%0.327CS..G310 helixtrans-60-23.1178.9-65.5-73.7000113.5V273 I285 D289 T293 R294 Q297 L300V273-Y287 HydrophobicContact CG1-CD1 3.85Å; V273-Y287 HydrophobicContact CG1-CE1 3.52Å; V273-Y287 HydrophobicContact CG2-CD1 4.23Å; I285-Y287 HydrophobicContact CB-CD2 3.83Å; I285-Y287 HydrophobicContact CB-CE2 3.47Å; I285-Y287 VanDerWaalsContact CB-CE2 3.47Å; I285-Y287 HydrophobicContact CG1-CE2 4.21Å; I285-Y287 HydrophobicContact CG2-CD1 4.34Å; I285-Y287 HydrophobicContact CG2-CD2 3.71Å; I285-Y287 HydrophobicContact CG2-CE1 4.01Å; I285-Y287 HydrophobicContact CG2-CE2 3.32Å; I285-Y287 HydrophobicContact CG2-CG 4.21Å; I285-Y287 VanDerWaalsContact CG2-CZ 3.49Å; I285-Y287 PolarHBondContact O-N 3.35Å; Y287-D289 VanDerWaalsContact C-N 3.34Å; Y287-T293 CarbonylContact O-C 3.59Å; Y287-T293 WeakPolarHBondContact O-CB 3.48Å; Y287-T293 PolarHBondContact O-OG1 3.3Å; Y287-R294 WeakPolarHBondContact O-CG 3.15Å; Y287-R294 PolarHBondContact O-N 3.32Å; Y287-Q297 HydrophobicContact CD1-CB 3.96Å; Y287-Q297 HydrophobicContact CD1-CG 3.88Å; Y287-Q297 HydrophobicContact CD2-CG 3.91Å; Y287-Q297 HydrophobicContact CE1-CB 4.28Å; Y287-Q297 HydrophobicContact CE1-CG 4.03Å; Y287-Q297 HydrophobicContact CE2-CG 4.04Å; Y287-Q297 HydrophobicContact CG-CB 4.23Å; Y287-Q297 HydrophobicContact CG-CG 3.82Å; Y287-L300 WeakPolarHBondContact CE1-O 3.38Å; Y287-L300 PolarHBondContact OH-O 2.7Å
288R92.7Very high90.3Very high177 Ų17764.2 Ų64.267%0.66833%0.332SS*.G310 helixtrans-80.2-11.4-176-71.5-173.9171.3-179.2-1.3114.5E164 P286 S290E164-R288 IonicContact OE1-NH2 2.97Å; E164-R288 IonicContact OE2-NH2 3.7Å; E164-R288 PolarHBondContact OE2-NH2 3.11Å; P286-R288 PolarHBondContact O-N 3.42Å; P286-R288 VanDerWaalsContact O-N 3.09Å; R288-S290 PolarHBondContact O-N 3Å
289D90.6Very high90.5Very high85 Ų8562.3 Ų62.346%0.45532%0.321SS..G310 helixtrans-67-21-176.5-70.98.7000112.8A269 P286 Y287A269-D289 HydrophobicContact CB-CB 3.87Å; P286-D289 WeakPolarHBondContact CB-OD2 3.26Å; P286-D289 PolarHBondContact O-N 3.14Å; Y287-D289 VanDerWaalsContact C-N 3.34Å
290S93.6Very high90.7Very high2 Ų257.3 Ų57.31%0.01429%0.294CS..  trans-142.5154.3171.478.30000112.4E146 R288 L292 T293 R294E146-S290 WeakPolarHBondContact OE2-CA 3.39Å; R288-S290 PolarHBondContact O-N 3Å; S290-L292 VanDerWaalsContact C-N 3.27Å; S290-L292 PolarHBondContact O-N 3.34Å; S290-T293 PolarHBondContact N-OG1 2.93Å; S290-T293 PolarHBondContact O-OG1 2.92Å; S290-T293 WeakPolarHBondContact OG-CB 3.34Å; S290-T293 WeakPolarHBondContact OG-CG2 3.25Å; S290-T293 PolarHBondContact OG-N 3.3Å; S290-T293 PolarHBondContact OG-OG1 3.23Å; S290-R294 WeakPolarHBondContact O-CG 3.36Å; S290-R294 PolarHBondContact O-N 2.88Å
291K93.9Very high91.1Very high73 Ų7355.8 Ų55.832%0.31728%0.279SS..Hα-helixtrans-62.8-35.9172.1-62-53.6178.9178.20111.7E146 V148 I162 R294 L295E146-K291 HydrophobicContact CB-CG 4.48Å; E146-K291 WeakPolarHBondContact O-CG 3.39Å; E146-K291 WeakPolarHBondContact OE2-CG 3.47Å; E146-K291 PolarHBondContact OE2-N 3.47Å; V148-K291 HydrophobicContact CG2-CB 4.22Å; V148-K291 HydrophobicContact CG2-CG 4.41Å; I162-K291 HydrophobicContact CD1-CB 3.7Å; I162-K291 HydrophobicContact CD1-CD 3.8Å; I162-K291 HydrophobicContact CD1-CG 4.19Å; I162-K291 WeakPolarHBondContact CD1-O 3.48Å; I162-K291 HydrophobicContact CG1-CD 4.35Å; K291-R294 PolarHBondContact O-N 3.01Å; K291-L295 WeakPolarHBondContact O-CG 3.4Å; K291-L295 PolarHBondContact O-N 3.26Å
292L94.7Very high91.6Very high0 Ų047.7 Ų47.70%025%0.248CC..Hα-helixtrans-60.2-51.3178177.768000111.5I143 H212 I214 L241 L270 S290 R294 L295 L296I143-L292 HydrophobicContact CD1-CB 4.08Å; I143-L292 HydrophobicContact CD1-CD1 3.94Å; H212-L292 HydrophobicContact CB-CD1 4.29Å; I214-L292 HydrophobicContact CD1-CD1 4.21Å; L241-L292 HydrophobicContact CD2-CD1 3.91Å; L241-L292 HydrophobicContact CD2-CD2 3.85Å; L241-L292 HydrophobicContact CD2-CG 4.48Å; L270-L292 HydrophobicContact CD2-CD2 4.39Å; S290-L292 VanDerWaalsContact C-N 3.27Å; S290-L292 PolarHBondContact O-N 3.34Å; L292-R294 VanDerWaalsContact C-N 3.26Å; L292-R294 PolarHBondContact O-N 2.95Å; L292-L295 PolarHBondContact O-N 3.42Å; L292-L295 VanDerWaalsContact O-N 3.15Å; L292-L296 HydrophobicContact CD1-CD1 3.83Å; L292-L296 HydrophobicContact CD1-CG 4.31Å; L292-L296 HydrophobicContact CG-CD1 4.11Å; L292-L296 PolarHBondContact O-N 3.22Å
293T94Very high92.3Very high1 Ų146.1 Ų46.11%0.00624%0.236CC..Hα-helixtrans-65-29.3179.147.60000112.6A269 L270 V273 Y287 S290 L296 Q297A269-T293 HydrophobicContact CB-CG2 4.31Å; L270-T293 HydrophobicContact CB-CG2 4.04Å; L270-T293 HydrophobicContact CD1-CG2 3.72Å; V273-T293 HydrophobicContact CG2-CG2 3.94Å; Y287-T293 CarbonylContact O-C 3.59Å; Y287-T293 WeakPolarHBondContact O-CB 3.48Å; Y287-T293 PolarHBondContact O-OG1 3.3Å; S290-T293 PolarHBondContact N-OG1 2.93Å; S290-T293 PolarHBondContact O-OG1 2.92Å; S290-T293 WeakPolarHBondContact OG-CB 3.34Å; S290-T293 WeakPolarHBondContact OG-CG2 3.25Å; S290-T293 PolarHBondContact OG-N 3.3Å; S290-T293 PolarHBondContact OG-OG1 3.23Å; T293-L296 CarbonylContact O-C 3.56Å; T293-Q297 WeakPolarHBondContact O-CA 3.42Å; T293-Q297 PolarHBondContact O-N 2.81Å
294R94.2Very high92.8Very high34 Ų3439 Ų3913%0.12819%0.192CC..Hα-helixtrans-67.1-43.2171.7-68.9-174.871.9-161.2-4.3111.8I162 E164 V170 Y287 S290 K291 L292 Q297I162-R294 HydrophobicContact CD1-CB 4.37Å; E164-R294 IonicContact OE1-CZ 3.22Å; E164-R294 IonicContact OE1-NE 3.62Å; E164-R294 IonicContact OE1-NH2 3.67Å; E164-R294 PolarHBondContact OE1-NH2 2.87Å; V170-R294 WeakPolarHBondContact CG1-O 3.42Å; Y287-R294 WeakPolarHBondContact O-CG 3.15Å; Y287-R294 PolarHBondContact O-N 3.32Å; S290-R294 WeakPolarHBondContact O-CG 3.36Å; S290-R294 PolarHBondContact O-N 2.88Å; K291-R294 PolarHBondContact O-N 3.01Å; L292-R294 VanDerWaalsContact C-N 3.26Å; L292-R294 PolarHBondContact O-N 2.95Å; R294-Q297 VanDerWaalsContact O-CB 3.3Å; R294-Q297 WeakPolarHBondContact O-CB 3.47Å; R294-Q297 PolarHBondContact O-N 3.41Å
295L94.3Very high93.1Very high29 Ų2933.3 Ų33.315%0.15217%0.166CC..Hα-helixtrans-68.4-36177.3-66.6179000112.3L141 I143 I162 V170 V172 I214 K291 L292 Q297L141-L295 HydrophobicContact CD1-CD1 4.19Å; L141-L295 HydrophobicContact CD2-CD1 4.32Å; I143-L295 HydrophobicContact CD1-CD1 3.76Å; I143-L295 HydrophobicContact CG1-CD1 4.46Å; I162-L295 HydrophobicContact CD1-CD1 4.18Å; I162-L295 HydrophobicContact CD1-CD2 3.76Å; I162-L295 HydrophobicContact CD1-CG 3.69Å; I162-L295 HydrophobicContact CG1-CD2 4.17Å; I162-L295 HydrophobicContact CG2-CD2 4.32Å; V170-L295 HydrophobicContact CG1-CD2 4.41Å; V172-L295 HydrophobicContact CG2-CD1 4.37Å; V172-L295 HydrophobicContact CG2-CD2 3.56Å; I214-L295 HydrophobicContact CD1-CB 4.45Å; I214-L295 HydrophobicContact CD1-CD1 4.1Å; K291-L295 WeakPolarHBondContact O-CG 3.4Å; K291-L295 PolarHBondContact O-N 3.26Å; L292-L295 PolarHBondContact O-N 3.42Å; L292-L295 VanDerWaalsContact O-N 3.15Å; L295-Q297 VanDerWaalsContact C-N 3.31Å
296L94Very high93.3Very high3 Ų332 Ų322%0.01616%0.159CC..THydrogen-bonded Turntrans-89.711178.3-61.7-179.2000113.8V239 L270 L292 T293 D298 S299 L300V239-L296 HydrophobicContact CG2-CD2 4.23Å; L270-L296 HydrophobicContact CD1-CD1 4.5Å; L292-L296 HydrophobicContact CD1-CD1 3.83Å; L292-L296 HydrophobicContact CD1-CG 4.31Å; L292-L296 HydrophobicContact CG-CD1 4.11Å; L292-L296 PolarHBondContact O-N 3.22Å; T293-L296 CarbonylContact O-C 3.56Å; L296-D298 VanDerWaalsContact C-N 3.27Å; L296-D298 PolarHBondContact O-N 2.87Å; L296-S299 WeakPolarHBondContact O-CA 3.25Å; L296-S299 WeakPolarHBondContact O-CB 3.46Å; L296-S299 PolarHBondContact O-N 2.88Å; L296-L300 HydrophobicContact CB-CD1 4.4Å; L296-L300 PolarHBondContact O-N 3.44Å
297Q92.9Very high93.5Very high69 Ų6931 Ų3132%0.32215%0.153SC..THydrogen-bonded Turntrans-58.7-39.7-178.3179.3177.7-17.100111.8Y287 T293 R294 L295Y287-Q297 HydrophobicContact CD1-CB 3.96Å; Y287-Q297 HydrophobicContact CD1-CG 3.88Å; Y287-Q297 HydrophobicContact CD2-CG 3.91Å; Y287-Q297 HydrophobicContact CE1-CB 4.28Å; Y287-Q297 HydrophobicContact CE1-CG 4.03Å; Y287-Q297 HydrophobicContact CE2-CG 4.04Å; Y287-Q297 HydrophobicContact CG-CB 4.23Å; Y287-Q297 HydrophobicContact CG-CG 3.82Å; T293-Q297 WeakPolarHBondContact O-CA 3.42Å; T293-Q297 PolarHBondContact O-N 2.81Å; R294-Q297 VanDerWaalsContact O-CB 3.3Å; R294-Q297 WeakPolarHBondContact O-CB 3.47Å; R294-Q297 PolarHBondContact O-N 3.41Å; L295-Q297 VanDerWaalsContact C-N 3.31Å
298D91.4Very high93.7Very high59 Ų5929.6 Ų29.632%0.31615%0.147SC..THydrogen-bonded Turntrans-74.8-29.5176.6-162.845.6000112.3N85 L296 G302 N303 T304N85-D298 PolarHBondContact ND2-OD2 3.3Å; N85-D298 VanDerWaalsContact ND2-OD2 3.15Å; L296-D298 VanDerWaalsContact C-N 3.27Å; L296-D298 PolarHBondContact O-N 2.87Å; D298-G302 CarbonylContact O-C 3.56Å; D298-G302 VanDerWaalsContact O-C 3.29Å; D298-G302 WeakPolarHBondContact O-CA 3.4Å; D298-G302 PolarHBondContact O-N 2.89Å; D298-N303 PolarHBondContact O-N 2.83Å; D298-N303 WeakPolarHBondContact OD1-CB 3.31Å; D298-N303 PolarHBondContact OD1-N 2.92Å; D298-T304 WeakPolarHBondContact O-CB 3.42Å; D298-T304 PolarHBondContact O-OG1 3.06Å; D298-T304 PolarHBondContact OD2-OG1 3.48Å; D298-T304 VanDerWaalsContact OD2-OG1 3.04Å
299S93.6Very high93.9Very high0 Ų021.2 Ų21.20%012%0.116CC..THydrogen-bonded Turntrans-70.8-27.6177.2-52.60000113.5T87 L296 T306 N337T87-S299 PolarHBondContact OG1-OG 2.94Å; L296-S299 WeakPolarHBondContact O-CA 3.25Å; L296-S299 WeakPolarHBondContact O-CB 3.46Å; L296-S299 PolarHBondContact O-N 2.88Å; S299-T306 WeakPolarHBondContact O-CB 3.46Å; S299-T306 PolarHBondContact O-OG1 2.94Å; S299-N337 PolarHBondContact O-ND2 3.31Å
300L91.6Very high94.3Very high2 Ų217.1 Ų17.11%0.019%0.094CC..THydrogen-bonded Turntrans-123.794.9-174.5-62174.2000110.6F89 L270 L277 Y287 L296 T306 I335F89-L300 HydrophobicContact CE1-CD2 4.11Å; F89-L300 HydrophobicContact CZ-CD2 4.29Å; L270-L300 HydrophobicContact CD1-CD1 3.4Å; L270-L300 VanDerWaalsContact CD1-CD1 3.4Å; L270-L300 HydrophobicContact CG-CD1 4.45Å; L277-L300 HydrophobicContact CD1-CB 4.17Å; L277-L300 WeakPolarHBondContact CD1-O 3.21Å; Y287-L300 WeakPolarHBondContact CE1-O 3.38Å; Y287-L300 PolarHBondContact OH-O 2.7Å; L296-L300 HydrophobicContact CB-CD1 4.4Å; L296-L300 PolarHBondContact O-N 3.44Å; L300-T306 HydrophobicContact CD2-CG2 4.46Å; L300-I335 HydrophobicContact CD2-CD1 4.13Å
301G89.2Confident94.5Very high30 Ų3017.1 Ų17.131%0.3099%0.094SC..THydrogen-bonded Turntrans92.50.3-176.300000114.7N337G301-N337 WeakPolarHBondContact CA-OD1 3.47Å; G301-N337 PolarHBondContact N-OD1 3.04Å
302G91.3Very high94.7Very high17 Ų1713.7 Ų13.718%0.1758%0.079CC..SBendtrans-108.1-151-176.100000115.2D298 T304 R338D298-G302 CarbonylContact O-C 3.56Å; D298-G302 VanDerWaalsContact O-C 3.29Å; D298-G302 WeakPolarHBondContact O-CA 3.4Å; D298-G302 PolarHBondContact O-N 2.89Å; G302-T304 PolarHBondContact O-N 2.91Å; G302-R338 PolarHBondContact O-N 3.06Å
303N92.8Very high94.7Very high15 Ų1513.7 Ų13.78%0.088%0.079CC..SBendtrans-92.760.7-177.8175.925.6000111.3N85 D298 P339 R340 N342N85-N303 WeakPolarHBondContact CB-O 3.48Å; N85-N303 PolarHBondContact ND2-O 3.04Å; N85-N303 VanDerWaalsContact ND2-O 3.08Å; D298-N303 PolarHBondContact O-N 2.83Å; D298-N303 WeakPolarHBondContact OD1-CB 3.31Å; D298-N303 PolarHBondContact OD1-N 2.92Å; N303-P339 WeakPolarHBondContact OD1-CA 3.37Å; N303-R340 HydrophobicContact CB-CG 4.47Å; N303-R340 WeakPolarHBondContact ND2-CG 3.38Å; N303-R340 PolarHBondContact ND2-NE 2.92Å; N303-R340 WeakPolarHBondContact OD1-CG 3.36Å; N303-R340 PolarHBondContact OD1-N 2.83Å; N303-R340 PolarHBondContact OD1-O 2.99Å; N303-N342 PolarHBondContact ND2-OD1 2.79Å
304T95.2Very high94.7Very high0 Ų013.6 Ų13.60%08%0.078CC..  trans-148.7139.7180-68.10000111N85 T87 D298 G302 N337N85-T304 HydrophobicContact CB-CG2 4.12Å; N85-T304 VanDerWaalsContact CB-OG1 3.3Å; N85-T304 WeakPolarHBondContact CB-OG1 3.18Å; T87-T304 WeakPolarHBondContact OG1-CG2 3.3Å; D298-T304 WeakPolarHBondContact O-CB 3.42Å; D298-T304 PolarHBondContact O-OG1 3.06Å; D298-T304 PolarHBondContact OD2-OG1 3.48Å; D298-T304 VanDerWaalsContact OD2-OG1 3.04Å; G302-T304 PolarHBondContact O-N 2.91Å; T304-N337 WeakPolarHBondContact O-CB 3.45Å; T304-N337 PolarHBondContact O-ND2 3.33Å
305K95.9Very high94.8Very high17 Ų1712 Ų127%0.0747%0.072CC..EExtended strand (participates in β ladder)trans-81.1119.1166.4-66.7-175.5-173.9172.70108.3L76 S79 Y84 N85 G86 T87 P339L76-K305 HydrophobicContact CD1-CB 3.42Å; L76-K305 VanDerWaalsContact CD1-CB 3.42Å; L76-K305 WeakPolarHBondContact CD1-O 3.42Å; S79-K305 VanDerWaalsContact CB-NZ 3.27Å; S79-K305 PolarHBondContact OG-NZ 3.16Å; Y84-K305 HydrophobicContact CG-CD 4.38Å; N85-K305 PolarHBondContact O-N 3.45Å; G86-K305 CarbonylContact C-O 3.57Å; G86-K305 WeakPolarHBondContact CA-O 3.22Å; T87-K305 PolarHBondContact N-O 3.29Å; K305-P339 HydrophobicContact CG-CB 3.57Å; K305-P339 HydrophobicContact CG-CG 3.85Å
306T97Very high94.8Very high6 Ų612.7 Ų12.74%0.0378%0.076CC..EExtended strand (participates in β ladder)trans-121.4131.4-169-58.70000111.1V7 R8 T87 F89 S299 L300 N337V7-T306 HydrophobicContact CG1-CG2 4.06Å; V7-T306 HydrophobicContact CG2-CG2 4.42Å; R8-T306 PolarHBondContact N-O 2.87Å; T87-T306 HydrophobicContact CG2-CG2 4.35Å; T87-T306 CarbonylContact O-C 3.6Å; T87-T306 WeakPolarHBondContact O-CA 3.28Å; F89-T306 HydrophobicContact CD1-CG2 3.94Å; F89-T306 HydrophobicContact CE1-CG2 3.46Å; F89-T306 VanDerWaalsContact CE1-CG2 3.46Å; S299-T306 WeakPolarHBondContact O-CB 3.46Å; S299-T306 PolarHBondContact O-OG1 2.94Å; L300-T306 HydrophobicContact CD2-CG2 4.46Å; T306-N337 PolarHBondContact OG1-ND2 2.73Å
307I97.2Very high94.7Very high2 Ų219.1 Ų19.11%0.0110%0.101CC..EExtended strand (participates in β ladder)trans-114.2124.7171.8-61.8172.7000108.1R8 V10 V72 L76 T87 V88 F89 I309R8-I307 HydrophobicContact CB-CG1 4.33Å; R8-I307 CarbonylContact O-C 3.42Å; R8-I307 WeakPolarHBondContact O-CA 3.33Å; V10-I307 HydrophobicContact CG2-CG2 4.35Å; V72-I307 HydrophobicContact CG1-CD1 3.7Å; V72-I307 HydrophobicContact CG1-CG1 4.24Å; V72-I307 HydrophobicContact CG1-CG2 4.04Å; L76-I307 HydrophobicContact CB-CD1 3.68Å; L76-I307 HydrophobicContact CD2-CD1 3.69Å; L76-I307 HydrophobicContact CD2-CG1 4.09Å; L76-I307 HydrophobicContact CG-CD1 4.22Å; T87-I307 PolarHBondContact O-N 2.69Å; V88-I307 WeakPolarHBondContact CA-O 3.04Å; V88-I307 HydrophobicContact CG2-CB 4.46Å; F89-I307 PolarHBondContact N-O 3.32Å; I307-I309 HydrophobicContact CG2-CG1 4.09Å
308M97.5Very high94.7Very high0 Ų016.3 Ų16.30%09%0.088CC..EExtended strand (participates in β ladder)trans-100.3126.4167.3176.1178.8173.600109.2V7 R8 V9 V10 F89 Y91 A310 Y328 A329 A332V7-M308 HydrophobicContact CG1-CB 4.35Å; R8-M308 PolarHBondContact O-N 3.39Å; V9-M308 HydrophobicContact CG2-CB 4.3Å; V10-M308 PolarHBondContact N-O 3.38Å; F89-M308 HydrophobicContact CD2-CB 4.41Å; F89-M308 HydrophobicContact CD2-CG 4.12Å; F89-M308 HydrophobicContact CE1-CB 4.15Å; F89-M308 HydrophobicContact CE2-CB 3.72Å; F89-M308 HydrophobicContact CE2-CG 3.42Å; F89-M308 VanDerWaalsContact CE2-CG 3.42Å; F89-M308 HydrophobicContact CE2-SD 3.89Å; F89-M308 HydrophobicContact CZ-CB 3.57Å; F89-M308 HydrophobicContact CZ-CG 3.78Å; F89-M308 HydrophobicContact CZ-SD 4.15Å; Y91-M308 HydrophobicContact CD1-CE 3.75Å; Y91-M308 HydrophobicContact CG-CE 3.91Å; M308-A310 HydrophobicContact CE-CB 4.22Å; M308-Y328 HydrophobicContact CE-CD1 3.55Å; M308-Y328 HydrophobicContact CE-CE1 3.94Å; M308-Y328 HydrophobicContact SD-CD1 4.25Å; M308-Y328 HydrophobicContact SD-CE1 4.32Å; M308-A329 HydrophobicContact CE-CB 3.92Å; M308-A329 HydrophobicContact SD-CB 4.41Å; M308-A332 HydrophobicContact SD-CB 3.57Å; M308-A332 VanDerWaalsContact SD-CB 3.57Å
309I98.1Very high94.8Very high1 Ų114 Ų141%0.0058%0.075CC..EExtended strand (participates in β ladder)trans-106.5107171.5-55.3172.3000108.2V10 L68 V88 F89 A90 Y91 T101 I114 I307 C311V10-I309 CarbonylContact O-C 3.55Å; V10-I309 WeakPolarHBondContact O-CA 3.45Å; L68-I309 HydrophobicContact CD1-CG2 4.45Å; L68-I309 HydrophobicContact CD2-CD1 4.06Å; V88-I309 HydrophobicContact CG1-CD1 3.63Å; V88-I309 HydrophobicContact CG1-CG1 4.26Å; F89-I309 PolarHBondContact O-N 2.78Å; A90-I309 CarbonylContact C-O 3.59Å; A90-I309 WeakPolarHBondContact CA-O 3.35Å; Y91-I309 PolarHBondContact N-O 2.84Å; T101-I309 HydrophobicContact CG2-CD1 4.18Å; T101-I309 HydrophobicContact CG2-CG2 4.24Å; I114-I309 HydrophobicContact CD1-CD1 3.24Å; I307-I309 HydrophobicContact CG2-CG1 4.09Å; I309-C311 PolarHBondContact O-N 2.88Å
310A97.8Very high94.6Very high0 Ų017.1 Ų17.10%09%0.09CC..EExtended strand (participates in β ladder)trans-84.5108.5173.900000109.8V10 V11 R12 Y91 M308 T325 A329V10-A310 PolarHBondContact O-N 3.39Å; V11-A310 WeakPolarHBondContact CA-O 3.4Å; V11-A310 HydrophobicContact CG2-CB 4.1Å; R12-A310 PolarHBondContact N-O 3.25Å; Y91-A310 WeakPolarHBondContact O-CA 3.46Å; M308-A310 HydrophobicContact CE-CB 4.22Å; A310-T325 HydrophobicContact CB-CG2 3.99Å; A310-A329 HydrophobicContact CB-CB 3.92Å
311C97.7Very high94.7Very high1 Ų117.2 Ų17.21%0.0079%0.09CC..EExtended strand (participates in β ladder)trans-94123.6178.9-62.70000110.4R12 Y91 S96 K98 I309R12-C311 WeakPolarHBondContact O-CA 3.39Å; Y91-C311 PolarHBondContact O-N 3.27Å; S96-C311 WeakPolarHBondContact CB-O 3.45Å; S96-C311 VanDerWaalsContact OG-CB 3.28Å; S96-C311 WeakPolarHBondContact OG-CB 3.39Å; S96-C311 PolarHBondContact OG-O 2.92Å; K98-C311 HydrophobicContact CG-CB 3.98Å; I309-C311 PolarHBondContact O-N 2.88Å
312L97.4Very high94.9Very high1 Ų115.8 Ų15.81%0.0058%0.076CC..EExtended strand (participates in β ladder)trans-116.6149.1-173.3-54.4178000112.4V11 R12 R14 L29 T325 L326V11-L312 HydrophobicContact CG1-CD1 3.37Å; V11-L312 HydrophobicContact CG1-CG 4.08Å; R12-L312 PolarHBondContact O-N 3.02Å; R14-L312 PolarHBondContact N-O 2.85Å; L29-L312 HydrophobicContact CD1-CB 3.6Å; L29-L312 HydrophobicContact CD1-CD1 3.95Å; L29-L312 HydrophobicContact CD1-CG 4.41Å; L29-L312 HydrophobicContact CD2-CD1 4.47Å; L312-T325 HydrophobicContact CD2-CG2 3.49Å; L312-T325 VanDerWaalsContact CD2-CG2 3.49Å; L312-L326 HydrophobicContact CD1-CD1 4.25Å; L312-L326 HydrophobicContact CD1-CD2 3.7Å; L312-L326 HydrophobicContact CD1-CG 3.91Å; L312-L326 HydrophobicContact CD2-CG 4.18Å
313S95.3Very high95.1Very high0 Ų015.1 Ų15.10%07%0.068CC..  trans-96.6134.7164.5171.30000109.7R14 E20 L29 A315 N318 S322R14-S313 PolarHBondContact NH2-OG 2.9Å; E20-S313 PolarHBondContact OE1-OG 3.25Å; L29-S313 VanDerWaalsContact CD1-O 3.23Å; L29-S313 WeakPolarHBondContact CD1-O 3.33Å; S313-A315 VanDerWaalsContact C-N 3.28Å; S313-A315 PolarHBondContact O-N 3.3Å; S313-A315 PolarHBondContact OG-N 3.31Å; S313-N318 PolarHBondContact OG-ND2 2.89Å; S313-N318 VanDerWaalsContact OG-ND2 3.1Å; S313-S322 PolarHBondContact N-OG 3.01Å; S313-S322 PolarHBondContact O-OG 3.2Å
314P95.4Very high95Very high0 Ų015.9 Ų15.90%08%0.075CC..  trans-80.2-6.3177.636.6-39.9000113.6R14 L16 Y27 V28 L29R14-P314 WeakPolarHBondContact O-CD 3.41Å; R14-P314 WeakPolarHBondContact O-CG 3.46Å; L16-P314 HydrophobicContact CD2-CG 3.9Å; L16-P314 HydrophobicContact CG-CG 4.23Å; Y27-P314 CarbonylContact C-O 3.58Å; Y27-P314 WeakPolarHBondContact CA-O 3.33Å; Y27-P314 HydrophobicContact CD1-CB 3.57Å; Y27-P314 HydrophobicContact CD1-CG 4.1Å; Y27-P314 HydrophobicContact CE1-CB 3.85Å; Y27-P314 HydrophobicContact CE1-CG 3.88Å; V28-P314 WeakPolarHBondContact CG2-O 3.46Å; V28-P314 PolarHBondContact N-O 2.99Å; L29-P314 HydrophobicContact CB-CB 4.32Å
315A95Very high95Very high0 Ų016 Ų160%08%0.075CC..BIsolated β-bridgetrans-73.3138.3-174.500000112.6L16 E20 C25 S313 Y317 N318 Y319L16-A315 HydrophobicContact CD2-CB 3.66Å; E20-A315 HydrophobicContact CB-CB 4.34Å; E20-A315 HydrophobicContact CG-CB 3.86Å; C25-A315 HydrophobicContact CB-CB 3.98Å; S313-A315 VanDerWaalsContact C-N 3.28Å; S313-A315 PolarHBondContact O-N 3.3Å; S313-A315 PolarHBondContact OG-N 3.31Å; A315-Y317 VanDerWaalsContact C-N 3.27Å; A315-Y317 PolarHBondContact O-N 2.96Å; A315-N318 HydrophobicContact CB-CB 4.45Å; A315-N318 CarbonylContact O-C 3.56Å; A315-N318 WeakPolarHBondContact O-CA 3.37Å; A315-N318 WeakPolarHBondContact O-CB 3.38Å; A315-N318 PolarHBondContact O-N 2.93Å; A315-Y319 PolarHBondContact O-N 3.41Å
316D94.6Very high95Very high43 Ų4315.1 Ų15.123%0.237%0.071CC..G310 helixtrans-51-41170.451.87.8000114.1C25 T26 V28 P43 N318 Y319C25-D316 WeakPolarHBondContact CA-OD1 3.26Å; C25-D316 VanDerWaalsContact CB-OD1 3.27Å; C25-D316 WeakPolarHBondContact CB-OD1 3.3Å; C25-D316 PolarHBondContact SG-OD1 2.81Å; T26-D316 VanDerWaalsContact N-CG 3.34Å; T26-D316 PolarHBondContact N-OD1 3.05Å; T26-D316 PolarHBondContact N-OD2 3.31Å; T26-D316 PolarHBondContact O-N 3.18Å; T26-D316 PolarHBondContact OG1-OD2 3.45Å; V28-D316 HydrophobicContact CG1-CB 3.66Å; P43-D316 HydrophobicContact CB-CB 3.95Å; P43-D316 HydrophobicContact CG-CB 4.19Å; D316-N318 PolarHBondContact O-N 3.31Å; D316-N318 VanDerWaalsContact O-N 3.1Å; D316-Y319 VanDerWaalsContact O-CB 3.24Å; D316-Y319 WeakPolarHBondContact O-CB 3.29Å; D316-Y319 PolarHBondContact O-N 3.37Å
317Y91.8Very high94.8Very high139 Ų13916 Ų1655%0.5457%0.074SC..G310 helixtrans-55.7-27.2174.2179.8-102.2000113.3K249 A315K249-Y317 PolarHBondContact NZ-O 3.04Å; A315-Y317 VanDerWaalsContact C-N 3.27Å; A315-Y317 PolarHBondContact O-N 2.96Å
318N92.4Very high94.6Very high9 Ų916.2 Ų16.25%0.0488%0.075CC..G310 helixtrans-104.44.7-177.7-73-40.1000113.6E20 Q93 S313 A315 D316 E320 E321 S322E20-N318 PolarHBondContact OE1-ND2 2.81Å; Q93-N318 VanDerWaalsContact NE2-CG 3.28Å; Q93-N318 PolarHBondContact NE2-OD1 2.71Å; Q93-N318 VanDerWaalsContact OE1-CB 3.24Å; Q93-N318 VanDerWaalsContact OE1-CG 3.3Å; Q93-N318 PolarHBondContact OE1-OD1 3.4Å; S313-N318 PolarHBondContact OG-ND2 2.89Å; S313-N318 VanDerWaalsContact OG-ND2 3.1Å; A315-N318 HydrophobicContact CB-CB 4.45Å; A315-N318 CarbonylContact O-C 3.56Å; A315-N318 WeakPolarHBondContact O-CA 3.37Å; A315-N318 WeakPolarHBondContact O-CB 3.38Å; A315-N318 PolarHBondContact O-N 2.93Å; D316-N318 PolarHBondContact O-N 3.31Å; D316-N318 VanDerWaalsContact O-N 3.1Å; N318-E320 VanDerWaalsContact C-N 3.31Å; N318-E320 PolarHBondContact O-N 2.72Å; N318-E321 PolarHBondContact O-N 3.06Å; N318-S322 PolarHBondContact O-N 3.03Å
319Y93.5Very high94.5Very high10 Ų1016.2 Ų16.24%0.0398%0.075CC..Hα-helixtrans-45.3-51.5-177.7169-99.2000113.4V28 I40 A41 N42 P43 A315 D316 E321 S322 L323V28-Y319 HydrophobicContact CB-CD2 4.42Å; V28-Y319 HydrophobicContact CG2-CD2 4.27Å; I40-Y319 HydrophobicContact CD1-CD2 3.65Å; I40-Y319 HydrophobicContact CD1-CE2 3.75Å; I40-Y319 HydrophobicContact CG1-CD2 3.75Å; I40-Y319 HydrophobicContact CG1-CE2 3.67Å; A41-Y319 WeakPolarHBondContact O-CD2 3.39Å; A41-Y319 VanDerWaalsContact O-CE2 3.22Å; A41-Y319 WeakPolarHBondContact O-CE2 3.46Å; N42-Y319 HydrophobicContact CB-CE1 4.41Å; N42-Y319 HydrophobicContact CB-CE2 4.17Å; N42-Y319 WeakPolarHBondContact CB-OH 3.43Å; P43-Y319 VanDerWaalsContact CD-CD2 3.42Å; P43-Y319 VanDerWaalsContact CD-CG 3.41Å; P43-Y319 HydrophobicContact CG-CD1 4.42Å; P43-Y319 HydrophobicContact CG-CD2 4.39Å; P43-Y319 HydrophobicContact CG-CG 3.99Å; A315-Y319 PolarHBondContact O-N 3.41Å; D316-Y319 VanDerWaalsContact O-CB 3.24Å; D316-Y319 WeakPolarHBondContact O-CB 3.29Å; D316-Y319 PolarHBondContact O-N 3.37Å; Y319-E321 VanDerWaalsContact C-N 3.32Å; Y319-E321 PolarHBondContact O-N 3.45Å; Y319-S322 PolarHBondContact O-N 3.15Å; Y319-L323 HydrophobicContact CE1-CD2 4.17Å; Y319-L323 WeakPolarHBondContact O-CB 3.42Å; Y319-L323 PolarHBondContact O-N 3.45Å
320E90.5Very high94.3Very high66 Ų6619.3 Ų19.331%0.3089%0.091SC..Hα-helixtrans-60.1-39.2-176.9-69.1-66.4148.400113.1N318 S324 R552N318-E320 VanDerWaalsContact C-N 3.31Å; N318-E320 PolarHBondContact O-N 2.72Å; E320-S324 WeakPolarHBondContact O-CB 3.34Å; E320-S324 PolarHBondContact O-N 2.95Å; E320-R552 IonicContact OE1-NH2 2.76Å; E320-R552 IonicContact OE2-CZ 2.67Å; E320-R552 IonicContact OE2-NE 3.71Å; E320-R552 PolarHBondContact OE2-NE 2.92Å; E320-R552 IonicContact OE2-NH2 3.58Å; E320-R552 PolarHBondContact OE2-NH2 3.33Å
321E92.1Very high94Very high4 Ų424.2 Ų24.22%0.01911%0.11CC..Hα-helixtrans-78.4-38.2-177.5-56.7-62.2172.800111.1Q93 E245 R246 K249 N318 Y319 S324 T325Q93-E321 HydrophobicContact CB-CB 4.17Å; Q93-E321 HydrophobicContact CG-CB 4.43Å; E245-E321 WeakPolarHBondContact CA-OE2 3.11Å; E245-E321 HydrophobicContact CB-CG 4.31Å; R246-E321 PolarHBondContact N-OE1 2.95Å; K249-E321 HydrophobicContact CD-CG 4.32Å; K249-E321 WeakPolarHBondContact CD-OE1 3.34Å; K249-E321 WeakPolarHBondContact CE-OE1 3.17Å; K249-E321 IonicContact NZ-OE1 3.26Å; N318-E321 PolarHBondContact O-N 3.06Å; Y319-E321 VanDerWaalsContact C-N 3.32Å; Y319-E321 PolarHBondContact O-N 3.45Å; E321-S324 PolarHBondContact O-N 3Å; E321-T325 WeakPolarHBondContact O-CB 3.36Å; E321-T325 PolarHBondContact O-N 3.32Å; E321-T325 PolarHBondContact O-OG1 2.83Å
322S94.9Very high93.9Very high1 Ų124.2 Ų24.21%0.00711%0.11CC..Hα-helixtrans-63.8-42.2172.5-72.10000111.1S313 N318 Y319 T325 L326S313-S322 PolarHBondContact N-OG 3.01Å; S313-S322 PolarHBondContact O-OG 3.2Å; N318-S322 PolarHBondContact O-N 3.03Å; Y319-S322 PolarHBondContact O-N 3.15Å; S322-T325 PolarHBondContact O-N 3.49Å; S322-L326 VanDerWaalsContact O-CG 3.3Å; S322-L326 WeakPolarHBondContact O-CG 3.42Å; S322-L326 PolarHBondContact O-N 3.38Å
323L93.9Very high93.6Very high3 Ų325.4 Ų25.42%0.01612%0.115CC..Hα-helixtrans-62.6-46.6174.9-18061.9000111.8I40 K51 F53 Y319 T325 L326 R327 E549I40-L323 HydrophobicContact CD1-CB 4.02Å; I40-L323 HydrophobicContact CG2-CD1 4.04Å; K51-L323 HydrophobicContact CD-CD1 3.78Å; F53-L323 HydrophobicContact CE2-CD1 4.01Å; F53-L323 HydrophobicContact CZ-CD1 3.91Å; Y319-L323 HydrophobicContact CE1-CD2 4.17Å; Y319-L323 WeakPolarHBondContact O-CB 3.42Å; Y319-L323 PolarHBondContact O-N 3.45Å; L323-T325 VanDerWaalsContact C-N 3.29Å; L323-T325 PolarHBondContact O-N 3Å; L323-L326 PolarHBondContact O-N 3.46Å; L323-R327 HydrophobicContact CD1-CG 4.49Å; L323-R327 WeakPolarHBondContact O-CG 3.36Å; L323-R327 PolarHBondContact O-N 2.95Å; L323-E549 WeakPolarHBondContact CD2-OE1 3.27Å
324S92Very high93.5Very high31 Ų3129.1 Ų29.122%0.21714%0.135CC..Hα-helixtrans-60.5-41.5177.2-171.30000111.5E320 E321 R327 Y328E320-S324 WeakPolarHBondContact O-CB 3.34Å; E320-S324 PolarHBondContact O-N 2.95Å; E321-S324 PolarHBondContact O-N 3Å; S324-R327 PolarHBondContact O-N 3.28Å; S324-Y328 VanDerWaalsContact O-CB 3.31Å; S324-Y328 WeakPolarHBondContact O-CB 3.36Å; S324-Y328 PolarHBondContact O-N 3.04Å
325T95Very high93.4Very high1 Ų129.1 Ų29.11%0.00614%0.135CC..Hα-helixtrans-62.6-43.3175.9-60.70000112.1Y91 A310 L312 E321 S322 L323 Y328 A329Y91-T325 HydrophobicContact CD1-CG2 3.86Å; Y91-T325 HydrophobicContact CE1-CG2 4.06Å; A310-T325 HydrophobicContact CB-CG2 3.99Å; L312-T325 HydrophobicContact CD2-CG2 3.49Å; L312-T325 VanDerWaalsContact CD2-CG2 3.49Å; E321-T325 WeakPolarHBondContact O-CB 3.36Å; E321-T325 PolarHBondContact O-N 3.32Å; E321-T325 PolarHBondContact O-OG1 2.83Å; S322-T325 PolarHBondContact O-N 3.49Å; L323-T325 VanDerWaalsContact C-N 3.29Å; L323-T325 PolarHBondContact O-N 3Å; T325-Y328 WeakPolarHBondContact O-CB 3.47Å; T325-Y328 PolarHBondContact O-N 2.79Å; T325-A329 VanDerWaalsContact O-CB 3.27Å; T325-A329 WeakPolarHBondContact O-CB 3.31Å; T325-A329 PolarHBondContact O-N 3.34Å
326L95.8Very high93.3Very high0 Ų036.7 Ų36.70%016%0.164CC..Hα-helixtrans-62.4-44.8175.6-75.6166.5000112.2V11 L29 C38 I40 F53 F55 L312 S322 L323 Y328 A329 N330V11-L326 HydrophobicContact CG2-CD2 4.14Å; L29-L326 HydrophobicContact CD2-CD1 4.23Å; C38-L326 HydrophobicContact CB-CD2 4.26Å; I40-L326 HydrophobicContact CB-CD1 4.13Å; I40-L326 HydrophobicContact CD1-CD1 4.12Å; I40-L326 HydrophobicContact CG2-CD1 3.98Å; F53-L326 HydrophobicContact CB-CD2 4.37Å; F53-L326 HydrophobicContact CD1-CB 4.35Å; F53-L326 HydrophobicContact CD2-CB 4.01Å; F53-L326 HydrophobicContact CD2-CD1 3.87Å; F53-L326 HydrophobicContact CD2-CD2 4.3Å; F53-L326 HydrophobicContact CD2-CG 4.3Å; F53-L326 HydrophobicContact CE1-CB 4.3Å; F53-L326 HydrophobicContact CE2-CB 3.95Å; F53-L326 HydrophobicContact CE2-CD1 3.97Å; F53-L326 HydrophobicContact CG-CB 4.21Å; F53-L326 HydrophobicContact CG-CD2 4.37Å; F53-L326 HydrophobicContact CZ-CB 4.1Å; F55-L326 HydrophobicContact CE2-CD2 3.48Å; F55-L326 VanDerWaalsContact CE2-CD2 3.48Å; F55-L326 HydrophobicContact CZ-CD2 3.64Å; L312-L326 HydrophobicContact CD1-CD1 4.25Å; L312-L326 HydrophobicContact CD1-CD2 3.7Å; L312-L326 HydrophobicContact CD1-CG 3.91Å; L312-L326 HydrophobicContact CD2-CG 4.18Å; S322-L326 VanDerWaalsContact O-CG 3.3Å; S322-L326 WeakPolarHBondContact O-CG 3.42Å; S322-L326 PolarHBondContact O-N 3.38Å; L323-L326 PolarHBondContact O-N 3.46Å; L326-Y328 VanDerWaalsContact C-N 3.34Å; L326-Y328 PolarHBondContact O-N 3.43Å; L326-A329 PolarHBondContact O-N 3.44Å; L326-N330 WeakPolarHBondContact O-CB 3.23Å; L326-N330 PolarHBondContact O-N 3.26Å
327R92.9Very high93.2Very high23 Ų2334.8 Ų34.89%0.08715%0.153CC..Hα-helixtrans-63.3-40.4176-74177.6165.6-173.3-6.4112F53 L323 S324 N330 R331 D542 D545 E549F53-R327 HydrophobicContact CE1-CG 4.18Å; F53-R327 HydrophobicContact CZ-CG 4.13Å; L323-R327 HydrophobicContact CD1-CG 4.49Å; L323-R327 WeakPolarHBondContact O-CG 3.36Å; L323-R327 PolarHBondContact O-N 2.95Å; S324-R327 PolarHBondContact O-N 3.28Å; R327-N330 PolarHBondContact O-N 2.93Å; R327-R331 PolarHBondContact O-N 3.29Å; R327-R331 VanDerWaalsContact O-N 3.15Å; R327-D542 PolarHBondContact NH2-O 3.41Å; R327-D542 IonicContact NH2-OD1 2.81Å; R327-D542 PolarHBondContact NH2-OD1 2.98Å; R327-D545 VanDerWaalsContact NH2-CB 3.29Å; R327-E549 IonicContact CZ-OE1 2.62Å; R327-E549 IonicContact CZ-OE2 3.36Å; R327-E549 IonicContact NE-OE1 3.41Å; R327-E549 IonicContact NH1-OE1 3.87Å; R327-E549 PolarHBondContact NH1-OE1 2.92Å; R327-E549 IonicContact NH1-OE2 2.67Å; R327-E549 PolarHBondContact NH1-OE2 2.8Å
328Y93.3Very high93.3Very high8 Ų835.9 Ų35.93%0.03116%0.156CC..Hα-helixtrans-61.6-49.8174.7-170.5-79.6000111.5Y91 L270 I274 M308 S324 T325 L326 N330 R331 A332Y91-Y328 HydrophobicContact CD1-CD1 4.14Å; Y91-Y328 HydrophobicContact CD1-CE1 4.5Å; Y91-Y328 HydrophobicContact CD2-CE1 4.28Å; Y91-Y328 AromaticContact CE1-CD1 3.91Å; Y91-Y328 HydrophobicContact CE1-CD1 3.91Å; Y91-Y328 HydrophobicContact CE1-CD2 4.42Å; Y91-Y328 HydrophobicContact CE1-CE1 4.4Å; Y91-Y328 AromaticContact CE1-CG 3.91Å; Y91-Y328 HydrophobicContact CE1-CG 3.91Å; Y91-Y328 HydrophobicContact CE2-CD1 4.42Å; Y91-Y328 HydrophobicContact CE2-CE1 4.12Å; Y91-Y328 HydrophobicContact CE2-CE2 4.28Å; Y91-Y328 HydrophobicContact CG-CE1 4.46Å; Y91-Y328 AromaticContact CZ-CD2 3.99Å; Y91-Y328 AromaticContact CZ-CG 3.93Å; L270-Y328 WeakPolarHBondContact CD2-OH 3.23Å; L270-Y328 WeakPolarHBondContact CG-OH 3.42Å; I274-Y328 HydrophobicContact CD1-CD1 4.27Å; I274-Y328 HydrophobicContact CD1-CE1 3.39Å; I274-Y328 HydrophobicContact CD1-CE2 4.23Å; I274-Y328 VanDerWaalsContact CD1-OH 3.23Å; I274-Y328 WeakPolarHBondContact CD1-OH 3.23Å; M308-Y328 HydrophobicContact CE-CD1 3.55Å; M308-Y328 HydrophobicContact CE-CE1 3.94Å; M308-Y328 HydrophobicContact SD-CD1 4.25Å; M308-Y328 HydrophobicContact SD-CE1 4.32Å; S324-Y328 VanDerWaalsContact O-CB 3.31Å; S324-Y328 WeakPolarHBondContact O-CB 3.36Å; S324-Y328 PolarHBondContact O-N 3.04Å; T325-Y328 WeakPolarHBondContact O-CB 3.47Å; T325-Y328 PolarHBondContact O-N 2.79Å; L326-Y328 VanDerWaalsContact C-N 3.34Å; L326-Y328 PolarHBondContact O-N 3.43Å; Y328-N330 VanDerWaalsContact C-N 3.33Å; Y328-N330 PolarHBondContact O-N 3.46Å; Y328-R331 PolarHBondContact O-N 2.98Å; Y328-A332 PolarHBondContact O-N 3.28Å
329A95.3Very high93.4Very high0 Ų035.9 Ų35.90%016%0.157CC..Hα-helixtrans-59.8-42.1177.700000111.8V9 F55 M308 A310 T325 L326 R331 A332 K333V9-A329 HydrophobicContact CG1-CB 3.65Å; F55-A329 HydrophobicContact CE1-CB 3.66Å; F55-A329 HydrophobicContact CZ-CB 4.16Å; M308-A329 HydrophobicContact CE-CB 3.92Å; M308-A329 HydrophobicContact SD-CB 4.41Å; A310-A329 HydrophobicContact CB-CB 3.92Å; T325-A329 VanDerWaalsContact O-CB 3.27Å; T325-A329 WeakPolarHBondContact O-CB 3.31Å; T325-A329 PolarHBondContact O-N 3.34Å; L326-A329 PolarHBondContact O-N 3.44Å; A329-R331 VanDerWaalsContact C-N 3.32Å; A329-R331 PolarHBondContact O-N 2.98Å; A329-A332 WeakPolarHBondContact O-CB 3.37Å; A329-A332 PolarHBondContact O-N 3.19Å; A329-A332 VanDerWaalsContact O-N 3.17Å; A329-K333 PolarHBondContact O-N 3.3Å
330N93.4Very high93.3Very high66 Ų6642.8 Ų42.835%0.35318%0.183SC..Hα-helixtrans-63.6-36.6177.9-170.749.8000112.4F53 F55 L326 R327 Y328 N334F53-N330 HydrophobicContact CD1-CB 4.28Å; F55-N330 HydrophobicContact CE1-CB 4.42Å; L326-N330 WeakPolarHBondContact O-CB 3.23Å; L326-N330 PolarHBondContact O-N 3.26Å; R327-N330 PolarHBondContact O-N 2.93Å; Y328-N330 VanDerWaalsContact C-N 3.33Å; Y328-N330 PolarHBondContact O-N 3.46Å; N330-N334 PolarHBondContact O-ND2 3.11Å
331R92.7Very high93.4Very high102 Ų10242.2 Ų42.239%0.38518%0.181SC..Hα-helixtrans-66.3-47.1170.9-71.3-173.9-69.2169.6-5.8111.2I274 S275 V278 R327 Y328 A329 K333 N334I274-R331 HydrophobicContact CG2-CB 3.86Å; S275-R331 PolarHBondContact OG-NH1 2.76Å; V278-R331 VanDerWaalsContact CG2-O 3.23Å; V278-R331 WeakPolarHBondContact CG2-O 3.42Å; R327-R331 PolarHBondContact O-N 3.29Å; R327-R331 VanDerWaalsContact O-N 3.15Å; Y328-R331 PolarHBondContact O-N 2.98Å; A329-R331 VanDerWaalsContact C-N 3.32Å; A329-R331 PolarHBondContact O-N 2.98Å; R331-K333 PolarHBondContact O-N 3.1Å; R331-N334 PolarHBondContact O-N 3.1Å; R331-N334 VanDerWaalsContact O-N 3.08Å
332A94.2Very high93.3Very high1 Ų143.2 Ų43.21%0.00819%0.187CC..Hα-helixtrans-57.6-34.2-177.600000113.4V9 I274 M308 Y328 A329 N334 I335V9-A332 HydrophobicContact CG2-CB 4.17Å; I274-A332 HydrophobicContact CD1-CB 4.07Å; M308-A332 HydrophobicContact SD-CB 3.57Å; M308-A332 VanDerWaalsContact SD-CB 3.57Å; Y328-A332 PolarHBondContact O-N 3.28Å; A329-A332 WeakPolarHBondContact O-CB 3.37Å; A329-A332 PolarHBondContact O-N 3.19Å; A329-A332 VanDerWaalsContact O-N 3.17Å; A332-N334 PolarHBondContact O-N 3.22Å; A332-N334 VanDerWaalsContact O-N 3.09Å; A332-I335 HydrophobicContact CB-CD1 4.28Å; A332-I335 WeakPolarHBondContact O-CB 3.47Å; A332-I335 VanDerWaalsContact O-CG1 3.31Å; A332-I335 WeakPolarHBondContact O-CG1 3.24Å; A332-I335 PolarHBondContact O-N 3.06Å
333K92.5Very high92.9Very high27 Ų2745.4 Ų45.412%0.11720%0.197CC..THydrogen-bonded Turntrans-55.7-27.3177.5-167.6-180-173.81790113.6C6 V9 T54 D56 A329 R331C6-K333 WeakPolarHBondContact CB-O 3.02Å; V9-K333 HydrophobicContact CB-CB 4.32Å; V9-K333 HydrophobicContact CG2-CB 3.81Å; V9-K333 HydrophobicContact CG2-CG 4.39Å; T54-K333 PolarHBondContact O-NZ 3.33Å; D56-K333 WeakPolarHBondContact OD1-CE 3.4Å; D56-K333 IonicContact OD1-NZ 3.32Å; A329-K333 PolarHBondContact O-N 3.3Å; R331-K333 PolarHBondContact O-N 3.1Å
334N92.1Very high92.4Very high78 Ų7847.5 Ų47.542%0.41721%0.208SC..THydrogen-bonded Turntrans-90.9-1.8-177.6-64.4-57.4000113.8V278 N330 R331 A332 R336V278-N334 HydrophobicContact CG1-CB 3.83Å; V278-N334 HydrophobicContact CG2-CB 3.98Å; N330-N334 PolarHBondContact O-ND2 3.11Å; R331-N334 PolarHBondContact O-N 3.1Å; R331-N334 VanDerWaalsContact O-N 3.08Å; A332-N334 PolarHBondContact O-N 3.22Å; A332-N334 VanDerWaalsContact O-N 3.09Å; N334-R336 PolarHBondContact O-N 3.14Å
335I93.3Very high91.7Very high0 Ų050.5 Ų50.50%023%0.227CC..PPolyproline II helixtrans-69.1130.7175-60.6169.2000109C6 V7 I274 L277 V278 L300 A332C6-I335 CarbonylContact C-O 3.52Å; C6-I335 VanDerWaalsContact CA-O 3.23Å; C6-I335 WeakPolarHBondContact CA-O 3.28Å; V7-I335 HydrophobicContact CB-CB 4.38Å; V7-I335 HydrophobicContact CG2-CB 3.71Å; V7-I335 HydrophobicContact CG2-CD1 4.44Å; V7-I335 HydrophobicContact CG2-CG2 3.79Å; V7-I335 PolarHBondContact N-O 2.94Å; I274-I335 HydrophobicContact CB-CD1 4.13Å; I274-I335 HydrophobicContact CD1-CD1 4.12Å; I274-I335 HydrophobicContact CG1-CD1 3.66Å; I274-I335 HydrophobicContact CG2-CD1 3.89Å; I274-I335 HydrophobicContact CG2-CG1 4.22Å; L277-I335 HydrophobicContact CB-CG1 4.43Å; L277-I335 HydrophobicContact CD1-CG2 4.09Å; V278-I335 HydrophobicContact CG2-CG1 3.96Å; L300-I335 HydrophobicContact CD2-CD1 4.13Å; A332-I335 HydrophobicContact CB-CD1 4.28Å; A332-I335 WeakPolarHBondContact O-CB 3.47Å; A332-I335 VanDerWaalsContact O-CG1 3.31Å; A332-I335 WeakPolarHBondContact O-CG1 3.24Å; A332-I335 PolarHBondContact O-N 3.06Å
336R92.1Very high90.9Very high159 Ų15957.6 Ų57.660%0.626%0.258SS*.EExtended strand (participates in β ladder)trans-103.7116.4179.5-76.3-175.1-93.5-91.81.6111.3N334N334-R336 PolarHBondContact O-N 3.14Å
337N93.8Very high90Very high3 Ų358.5 Ų58.52%0.01626%0.263CS..EExtended strand (participates in β ladder)trans-100.4161.7173-71.54.4000111.3S4 E5 S299 G301 T304 T306 P339S4-N337 WeakPolarHBondContact CA-O 3.44Å; E5-N337 PolarHBondContact N-O 3.02Å; E5-N337 PolarHBondContact O-N 3.45Å; S299-N337 PolarHBondContact O-ND2 3.31Å; G301-N337 WeakPolarHBondContact CA-OD1 3.47Å; G301-N337 PolarHBondContact N-OD1 3.04Å; T304-N337 WeakPolarHBondContact O-CB 3.45Å; T304-N337 PolarHBondContact O-ND2 3.33Å; T306-N337 PolarHBondContact OG1-ND2 2.73Å; N337-P339 VanDerWaalsContact C-CD 3.48Å
338R93.9Very high89.3Confident161 Ų16158.9 Ų58.961%0.60827%0.271SS*.  trans-126.868.9177.8-64.7-175.9-179.6-162.60.3111G302 R340G302-R338 PolarHBondContact O-N 3.06Å; R338-R340 PolarHBondContact O-N 3.35Å
339P93.6Very high88.8Confident10 Ų1062.1 Ų62.17%0.06529%0.288CS..  trans-64.1134.2179.128.6-34.9000111.3E5 Y84 N303 K305 N337E5-P339 HydrophobicContact CB-CG 4.19Å; Y84-P339 HydrophobicContact CD1-CB 4Å; Y84-P339 HydrophobicContact CE1-CB 4.42Å; N303-P339 WeakPolarHBondContact OD1-CA 3.37Å; K305-P339 HydrophobicContact CG-CB 3.57Å; K305-P339 HydrophobicContact CG-CG 3.85Å; N337-P339 VanDerWaalsContact C-CD 3.48Å
340R91.5Very high88Confident154 Ų15465.9 Ų65.958%0.58131%0.308SS*.  trans-133.4156.7172.456.5170.7-175.6-156.35.2109.4P2 Y84 N303 R338P2-R340 HydrophobicContact CB-CB 4.49Å; Y84-R340 WeakPolarHBondContact CD1-O 3.39Å; N303-R340 HydrophobicContact CB-CG 4.47Å; N303-R340 WeakPolarHBondContact ND2-CG 3.38Å; N303-R340 PolarHBondContact ND2-NE 2.92Å; N303-R340 WeakPolarHBondContact OD1-CG 3.36Å; N303-R340 PolarHBondContact OD1-N 2.83Å; N303-R340 PolarHBondContact OD1-O 2.99Å; R338-R340 PolarHBondContact O-N 3.35Å
341I92.2Very high87.4Confident54 Ų5468.9 Ų68.928%0.27731%0.314SS..BIsolated β-bridgetrans-71.2129.2171.6-58.7177.2000107.5G83 Y84 K232 E343G83-I341 WeakPolarHBondContact O-CA 3.48Å; Y84-I341 HydrophobicContact CD1-CG1 4.35Å; Y84-I341 HydrophobicContact CD2-CG1 4.18Å; Y84-I341 HydrophobicContact CE1-CG1 3.86Å; Y84-I341 HydrophobicContact CE2-CD1 4.12Å; Y84-I341 HydrophobicContact CE2-CG1 3.65Å; Y84-I341 VanDerWaalsContact CZ-CG1 3.45Å; K232-I341 HydrophobicContact CD-CG2 4.2Å; K232-I341 HydrophobicContact CG-CG2 4.33Å; I341-E343 HydrophobicContact CG2-CG 3.97Å; I341-E343 PolarHBondContact O-N 3.24Å
342N90.3Very high86.9Confident25 Ų2569.9 Ų69.913%0.13432%0.324CS..EExtended strand (participates in β ladder)trans-88.2101.4175.8-42.5-67.4000109.1G83 N85 K232 T233 N303G83-N342 PolarHBondContact O-N 3.5Å; G83-N342 PolarHBondContact O-ND2 2.86Å; N85-N342 PolarHBondContact OD1-ND2 3.41Å; K232-N342 CarbonylContact C-O 3.47Å; K232-N342 VanDerWaalsContact CA-O 3.25Å; K232-N342 WeakPolarHBondContact CA-O 3.44Å; T233-N342 PolarHBondContact N-O 3.42Å; T233-N342 VanDerWaalsContact O-CB 3.31Å; T233-N342 WeakPolarHBondContact O-CB 3.25Å; T233-N342 PolarHBondContact O-ND2 2.79Å; T233-N342 WeakPolarHBondContact OG1-CB 3.27Å; N303-N342 PolarHBondContact ND2-OD1 2.79Å
343E87.3Confident86.4Confident48 Ų4876.3 Ų76.322%0.22435%0.349CS..EExtended strand (participates in β ladder)trans-99.1156.1173.2-64.7166.3-173.200108.9K232 I341 D347 A348 R351K232-E343 HydrophobicContact CG-CG 4.19Å; I341-E343 HydrophobicContact CG2-CG 3.97Å; I341-E343 PolarHBondContact O-N 3.24Å; E343-D347 HydrophobicContact CB-CB 4.49Å; E343-A348 HydrophobicContact CB-CB 4.47Å; E343-R351 IonicContact OE1-NH1 3.92Å; E343-R351 IonicContact OE2-NH1 3.07Å
344D82.8Confident85.8Confident47 Ų4780 Ų8025%0.25137%0.366SS..  trans-52.9134.7168-177.5-23.5000109.1I231 K346 D347 A348I231-D344 HydrophobicContact CB-CB 4.37Å; I231-D344 PolarHBondContact O-N 3.45Å; D344-K346 PolarHBondContact O-N 2.67Å; D344-K346 PolarHBondContact OD1-N 3.09Å; D344-D347 HydrophobicContact CB-CB 4.35Å; D344-D347 PolarHBondContact O-N 2.72Å; D344-A348 PolarHBondContact O-N 2.88Å
345P78.1Confident85.4Confident94 Ų9481.2 Ų81.261%0.6137%0.369SS*.Hα-helixtrans-41.4-38.1169.7-30.832000114.9L349P345-L349 VanDerWaalsContact O-CB 3.27Å; P345-L349 WeakPolarHBondContact O-CB 2.98Å; P345-L349 PolarHBondContact O-N 2.91Å
346K76.9Confident85.1Confident149 Ų14984.8 Ų84.865%0.64839%0.386SS*.Hα-helixtrans-66-47.6177.7-65.9175.4-175.3169.80111.9D344 L349 L350D344-K346 PolarHBondContact O-N 2.67Å; D344-K346 PolarHBondContact OD1-N 3.09Å; K346-L349 PolarHBondContact O-N 3.4Å; K346-L350 WeakPolarHBondContact O-CB 3.35Å; K346-L350 WeakPolarHBondContact O-CD1 3.36Å; K346-L350 WeakPolarHBondContact O-CG 3.3Å; K346-L350 PolarHBondContact O-N 3.35Å
347D78.4Confident84.9Confident20 Ų2081.4 Ų81.411%0.10738%0.379CS..Hα-helixtrans-65.1-43178.1-75.3-37000111.4H230 I231 E343 D344 L349 L350 R351H230-D347 VanDerWaalsContact CA-OD2 3.29Å; H230-D347 WeakPolarHBondContact CA-OD2 3.48Å; H230-D347 IonicContact CE1-OD1 3.81Å; H230-D347 VanDerWaalsContact ND1-CG 3.32Å; H230-D347 IonicContact ND1-OD1 2.82Å; H230-D347 PolarHBondContact ND1-OD1 2.86Å; H230-D347 IonicContact ND1-OD2 3.87Å; I231-D347 PolarHBondContact N-OD2 2.82Å; E343-D347 HydrophobicContact CB-CB 4.49Å; D344-D347 HydrophobicContact CB-CB 4.35Å; D344-D347 PolarHBondContact O-N 2.72Å; D347-L349 VanDerWaalsContact C-N 3.34Å; D347-L349 PolarHBondContact O-N 3.42Å; D347-L350 PolarHBondContact O-N 3.19Å; D347-R351 WeakPolarHBondContact O-CB 3.39Å; D347-R351 PolarHBondContact O-N 2.81Å
348A78.1Confident84.6Confident31 Ų3187.5 Ų87.526%0.25641%0.407SS..Hα-helixtrans-60.2-43.7176.400000111.6E343 D344 R351 Q352E343-A348 HydrophobicContact CB-CB 4.47Å; D344-A348 PolarHBondContact O-N 2.88Å; A348-R351 PolarHBondContact O-N 3.01Å; A348-Q352 WeakPolarHBondContact O-CG 3.49Å; A348-Q352 PolarHBondContact O-N 2.57Å
349L82Confident84.3Confident75 Ų7586 Ų8639%0.39340%0.401SS..Hα-helixtrans-67.1-43.7177.7-173.165.8000111.7P345 K346 D347 R351 Q352 Y353P345-L349 VanDerWaalsContact O-CB 3.27Å; P345-L349 WeakPolarHBondContact O-CB 2.98Å; P345-L349 PolarHBondContact O-N 2.91Å; K346-L349 PolarHBondContact O-N 3.4Å; D347-L349 VanDerWaalsContact C-N 3.34Å; D347-L349 PolarHBondContact O-N 3.42Å; L349-R351 VanDerWaalsContact C-N 3.32Å; L349-R351 PolarHBondContact O-N 3.29Å; L349-Q352 PolarHBondContact O-N 3.23Å; L349-Y353 HydrophobicContact CD1-CE1 4.06Å; L349-Y353 HydrophobicContact CD1-CE2 3.94Å; L349-Y353 HydrophobicContact CD2-CE2 3.77Å; L349-Y353 HydrophobicContact CG-CD2 4.03Å; L349-Y353 HydrophobicContact CG-CE1 4.5Å; L349-Y353 HydrophobicContact CG-CE2 3.49Å; L349-Y353 VanDerWaalsContact CG-CE2 3.49Å; L349-Y353 WeakPolarHBondContact O-CD2 3.35Å; L349-Y353 PolarHBondContact O-N 3.33Å
350L79.9Confident84Confident80 Ų8089.2 Ų89.242%0.41942%0.418SS..Hα-helixtrans-57.9-44.3175.1-82.9159.9000111.8K346 D347 Y353 Q354K346-L350 WeakPolarHBondContact O-CB 3.35Å; K346-L350 WeakPolarHBondContact O-CD1 3.36Å; K346-L350 WeakPolarHBondContact O-CG 3.3Å; K346-L350 PolarHBondContact O-N 3.35Å; D347-L350 PolarHBondContact O-N 3.19Å; L350-Y353 PolarHBondContact O-N 3.41Å; L350-Q354 WeakPolarHBondContact O-CB 3.23Å; L350-Q354 VanDerWaalsContact O-CG 3.3Å; L350-Q354 WeakPolarHBondContact O-CG 3.35Å; L350-Q354 PolarHBondContact O-N 3.5Å
351R79.4Confident83.7Confident128 Ų12888 Ų8848%0.48342%0.417SS..Hα-helixtrans-64.6-41.3177.6-175177.6176-144.6-2.6112.1E343 D347 A348 L349 Q354 Q355E343-R351 IonicContact OE1-NH1 3.92Å; E343-R351 IonicContact OE2-NH1 3.07Å; D347-R351 WeakPolarHBondContact O-CB 3.39Å; D347-R351 PolarHBondContact O-N 2.81Å; A348-R351 PolarHBondContact O-N 3.01Å; L349-R351 VanDerWaalsContact C-N 3.32Å; L349-R351 PolarHBondContact O-N 3.29Å; R351-Q354 PolarHBondContact O-N 3.15Å; R351-Q355 WeakPolarHBondContact O-CG 3.46Å; R351-Q355 PolarHBondContact O-N 2.8Å
352Q82Confident83.4Confident124 Ų12486.4 Ų86.458%0.57941%0.413SS*.Hα-helixtrans-61.8-44.5173.7-74.21805.500111.4A348 L349 Q354 Q355 E356A348-Q352 WeakPolarHBondContact O-CG 3.49Å; A348-Q352 PolarHBondContact O-N 2.57Å; L349-Q352 PolarHBondContact O-N 3.23Å; Q352-Q354 PolarHBondContact O-N 2.9Å; Q352-Q355 PolarHBondContact O-N 3.38Å; Q352-E356 WeakPolarHBondContact O-CB 3.46Å; Q352-E356 PolarHBondContact O-N 3.34Å
353Y84.6Confident83.1Confident136 Ų13689 Ų8953%0.53343%0.427SS..Hα-helixtrans-63.7-39.1175.4-68.9-28.7000112.6L349 L350 E356 I357L349-Y353 HydrophobicContact CD1-CE1 4.06Å; L349-Y353 HydrophobicContact CD1-CE2 3.94Å; L349-Y353 HydrophobicContact CD2-CE2 3.77Å; L349-Y353 HydrophobicContact CG-CD2 4.03Å; L349-Y353 HydrophobicContact CG-CE1 4.5Å; L349-Y353 HydrophobicContact CG-CE2 3.49Å; L349-Y353 VanDerWaalsContact CG-CE2 3.49Å; L349-Y353 WeakPolarHBondContact O-CD2 3.35Å; L349-Y353 PolarHBondContact O-N 3.33Å; L350-Y353 PolarHBondContact O-N 3.41Å; Y353-E356 PolarHBondContact O-N 3.21Å; Y353-I357 WeakPolarHBondContact O-CB 3.37Å; Y353-I357 WeakPolarHBondContact O-CD1 3.47Å; Y353-I357 WeakPolarHBondContact O-CG1 3.42Å; Y353-I357 PolarHBondContact O-N 2.86Å
354Q79.2Confident82.8Confident105 Ų10591.8 Ų91.849%0.49144%0.443SS..Hα-helixtrans-62.8-46174.8-75.4173.3-7.400112.1L350 R351 Q352 E356 I357 E358L350-Q354 WeakPolarHBondContact O-CB 3.23Å; L350-Q354 VanDerWaalsContact O-CG 3.3Å; L350-Q354 WeakPolarHBondContact O-CG 3.35Å; L350-Q354 PolarHBondContact O-N 3.5Å; R351-Q354 PolarHBondContact O-N 3.15Å; Q352-Q354 PolarHBondContact O-N 2.9Å; Q354-E356 VanDerWaalsContact C-N 3.32Å; Q354-E356 PolarHBondContact O-N 3.05Å; Q354-I357 PolarHBondContact O-N 2.81Å; Q354-E358 WeakPolarHBondContact O-CB 3.2Å; Q354-E358 PolarHBondContact O-N 3.46Å
355Q85Confident82.7Confident102 Ų10296.9 Ų96.948%0.47746%0.458SS..Hα-helixtrans-62.1-40.5175.7-73.6175.513.200111.8R351 Q352 E358 R359R351-Q355 WeakPolarHBondContact O-CG 3.46Å; R351-Q355 PolarHBondContact O-N 2.8Å; Q352-Q355 PolarHBondContact O-N 3.38Å; Q355-E358 PolarHBondContact O-N 2.91Å; Q355-R359 WeakPolarHBondContact O-CB 3.45Å; Q355-R359 PolarHBondContact O-N 3.35Å
356E86.2Confident82.4Confident75 Ų7597.5 Ų97.535%0.3546%0.456SS..Hα-helixtrans-69-40.7178.2-174.257.9-164.400111.6Q352 Y353 Q354 E358 R359 L360Q352-E356 WeakPolarHBondContact O-CB 3.46Å; Q352-E356 PolarHBondContact O-N 3.34Å; Y353-E356 PolarHBondContact O-N 3.21Å; Q354-E356 VanDerWaalsContact C-N 3.32Å; Q354-E356 PolarHBondContact O-N 3.05Å; E356-E358 VanDerWaalsContact C-N 3.3Å; E356-E358 PolarHBondContact O-N 2.97Å; E356-R359 PolarHBondContact O-N 2.97Å; E356-R359 IonicContact OE1-CZ 3.56Å; E356-R359 IonicContact OE1-NE 3.98Å; E356-R359 PolarHBondContact OE1-NE 2.83Å; E356-R359 IonicContact OE1-NH2 2.9Å; E356-R359 PolarHBondContact OE1-NH2 2.78Å; E356-R359 IonicContact OE2-CZ 2.72Å; E356-R359 IonicContact OE2-NE 3.79Å; E356-R359 PolarHBondContact OE2-NE 3.38Å; E356-R359 IonicContact OE2-NH2 3.44Å; E356-L360 HydrophobicContact CG-CD1 4.02Å; E356-L360 HydrophobicContact CG-CG 4.44Å; E356-L360 WeakPolarHBondContact O-CB 3.41Å; E356-L360 VanDerWaalsContact O-CG 3.23Å; E356-L360 WeakPolarHBondContact O-CG 3.37Å; E356-L360 PolarHBondContact O-N 3.36Å
357I87.6Confident82.1Confident88 Ų8896.1 Ų96.145%0.45146%0.46SS..Hα-helixtrans-59.7-42.4172-72.2164.2000110.4Y353 Q354 K361Y353-I357 WeakPolarHBondContact O-CB 3.37Å; Y353-I357 WeakPolarHBondContact O-CD1 3.47Å; Y353-I357 WeakPolarHBondContact O-CG1 3.42Å; Y353-I357 PolarHBondContact O-N 2.86Å; Q354-I357 PolarHBondContact O-N 2.81Å; I357-K361 HydrophobicContact CG2-CD 3.97Å; I357-K361 HydrophobicContact CG2-CG 4.41Å; I357-K361 VanDerWaalsContact O-CB 3.27Å; I357-K361 WeakPolarHBondContact O-CB 3.34Å; I357-K361 WeakPolarHBondContact O-CG 3.45Å; I357-K361 PolarHBondContact O-N 2.9Å
358E88.3Confident81.2Confident131 Ų131102.6 Ų102.661%0.61249%0.49SS*.Hα-helixtrans-66.3-43.1177.5-172.4172.3-16400112Q354 Q355 E356 K361 G362Q354-E358 WeakPolarHBondContact O-CB 3.2Å; Q354-E358 PolarHBondContact O-N 3.46Å; Q355-E358 PolarHBondContact O-N 2.91Å; E356-E358 VanDerWaalsContact C-N 3.3Å; E356-E358 PolarHBondContact O-N 2.97Å; E358-K361 PolarHBondContact O-N 3.35Å; E358-G362 PolarHBondContact O-N 2.92Å
359R87Confident79.9Confident129 Ų129107.3 Ų107.349%0.48751%0.507SS..Hα-helixtrans-60.4-47.7175-169.7-169.476.281.43.5111.5Q355 E356 G362 L363Q355-R359 WeakPolarHBondContact O-CB 3.45Å; Q355-R359 PolarHBondContact O-N 3.35Å; E356-R359 PolarHBondContact O-N 2.97Å; E356-R359 IonicContact OE1-CZ 3.56Å; E356-R359 IonicContact OE1-NE 3.98Å; E356-R359 PolarHBondContact OE1-NE 2.83Å; E356-R359 IonicContact OE1-NH2 2.9Å; E356-R359 PolarHBondContact OE1-NH2 2.78Å; E356-R359 IonicContact OE2-CZ 2.72Å; E356-R359 IonicContact OE2-NE 3.79Å; E356-R359 PolarHBondContact OE2-NE 3.38Å; E356-R359 IonicContact OE2-NH2 3.44Å; R359-G362 WeakPolarHBondContact O-CA 3.34Å; R359-G362 PolarHBondContact O-N 2.99Å; R359-L363 PolarHBondContact O-N 2.96Å
360L86.7Confident78.2Confident79 Ų79109.7 Ų109.741%0.41453%0.527SS..Hα-helixtrans-64.7-41.7177.6-71.1169.7000111.4E356 G362 L363 L364E356-L360 HydrophobicContact CG-CD1 4.02Å; E356-L360 HydrophobicContact CG-CG 4.44Å; E356-L360 WeakPolarHBondContact O-CB 3.41Å; E356-L360 VanDerWaalsContact O-CG 3.23Å; E356-L360 WeakPolarHBondContact O-CG 3.37Å; E356-L360 PolarHBondContact O-N 3.36Å; L360-G362 VanDerWaalsContact C-N 3.29Å; L360-G362 PolarHBondContact O-N 3.02Å; L360-L363 PolarHBondContact O-N 3.46Å; L360-L364 WeakPolarHBondContact O-CB 3.5Å; L360-L364 WeakPolarHBondContact O-CG 3.33Å; L360-L364 PolarHBondContact O-N 3.04Å
361K86.4Confident76.6Confident129 Ų129112 Ų11256%0.56154%0.544SS*.Hα-helixtrans-62.8-33.8171.8-77.1176.8178.2-178.40112.5I357 E358 R365I357-K361 HydrophobicContact CG2-CD 3.97Å; I357-K361 HydrophobicContact CG2-CG 4.41Å; I357-K361 VanDerWaalsContact O-CB 3.27Å; I357-K361 WeakPolarHBondContact O-CB 3.34Å; I357-K361 WeakPolarHBondContact O-CG 3.45Å; I357-K361 PolarHBondContact O-N 2.9Å; E358-K361 PolarHBondContact O-N 3.35Å; K361-R365 WeakPolarHBondContact O-CG 3.31Å; K361-R365 PolarHBondContact O-N 3.46Å; K361-R365 PolarHBondContact O-NE 3.3Å
362G84.5Confident74.6Confident19 Ų19114.5 Ų114.520%0.19656%0.562CS.*Hα-helixtrans-66.9-47172.800000112.4E358 R359 L360 R365 N366E358-G362 PolarHBondContact O-N 2.92Å; R359-G362 WeakPolarHBondContact O-CA 3.34Å; R359-G362 PolarHBondContact O-N 2.99Å; L360-G362 VanDerWaalsContact C-N 3.29Å; L360-G362 PolarHBondContact O-N 3.02Å; G362-R365 WeakPolarHBondContact O-CB 3.37Å; G362-R365 PolarHBondContact O-N 3.2Å; G362-N366 PolarHBondContact O-N 2.87Å; G362-N366 VanDerWaalsContact O-N 3.09Å
363L85.4Confident72.7Confident80 Ų80113 Ų11342%0.41957%0.571SS.*Hα-helixtrans-62.9-42.6176.1-73.8177.3000112.4R359 L360 R365 N366 V367R359-L363 PolarHBondContact O-N 2.96Å; L360-L363 PolarHBondContact O-N 3.46Å; L363-R365 VanDerWaalsContact C-N 3.28Å; L363-R365 PolarHBondContact O-N 2.72Å; L363-N366 PolarHBondContact O-N 2.9Å; L363-N366 VanDerWaalsContact O-N 3.09Å; L363-V367 WeakPolarHBondContact O-CG2 3.49Å; L363-V367 PolarHBondContact O-N 3.01Å
364L81.1Confident70.3Confident107 Ų107115.2 Ų115.256%0.5659%0.585SS**Hα-helixtrans-59.6-39.3174.9-77.7166.7000111.9L360 N366 V367 Q368L360-L364 WeakPolarHBondContact O-CB 3.5Å; L360-L364 WeakPolarHBondContact O-CG 3.33Å; L360-L364 PolarHBondContact O-N 3.04Å; L364-N366 VanDerWaalsContact C-N 3.34Å; L364-N366 PolarHBondContact O-N 3.21Å; L364-V367 PolarHBondContact O-N 3.46Å; L364-Q368 WeakPolarHBondContact O-CB 3.4Å; L364-Q368 WeakPolarHBondContact O-CG 3.41Å; L364-Q368 PolarHBondContact O-N 3.41Å
365R80.3Confident68.1Low154 Ų154116.2 Ų116.258%0.58160%0.599SS**Hα-helixtrans-62.5-38.8173.3-82.6-175.2-77.6169.8-5.6112.6K361 G362 L363 Q368 Q369K361-R365 WeakPolarHBondContact O-CG 3.31Å; K361-R365 PolarHBondContact O-N 3.46Å; K361-R365 PolarHBondContact O-NE 3.3Å; G362-R365 WeakPolarHBondContact O-CB 3.37Å; G362-R365 PolarHBondContact O-N 3.2Å; L363-R365 VanDerWaalsContact C-N 3.28Å; L363-R365 PolarHBondContact O-N 2.72Å; R365-Q368 PolarHBondContact O-N 2.79Å; R365-Q369 PolarHBondContact O-N 3.26Å
366N71.1Confident66Low106 Ų106117.2 Ų117.257%0.56761%0.614SS**Hα-helixtrans-73.3-36178.9-67.8-10.7000112.6G362 L363 L364 Q368 Q369G362-N366 PolarHBondContact O-N 2.87Å; G362-N366 VanDerWaalsContact O-N 3.09Å; L363-N366 PolarHBondContact O-N 2.9Å; L363-N366 VanDerWaalsContact O-N 3.09Å; L364-N366 VanDerWaalsContact C-N 3.34Å; L364-N366 PolarHBondContact O-N 3.21Å; N366-Q368 VanDerWaalsContact C-N 3.3Å; N366-Q369 PolarHBondContact O-N 3.28Å
367V71.2Confident63.3Low121 Ų121119.3 Ų119.373%0.73364%0.637SS**Hα-helixtrans-69.3-31.1174.8174.40000111.4L363 L364 Q369L363-V367 WeakPolarHBondContact O-CG2 3.49Å; L363-V367 PolarHBondContact O-N 3.01Å; L364-V367 PolarHBondContact O-N 3.46Å; V367-Q369 VanDerWaalsContact C-N 3.27Å; V367-Q369 PolarHBondContact O-N 2.86Å
368Q59.6Low60.9Low155 Ų155122.8 Ų122.872%0.72466%0.655SS**THydrogen-bonded Turntrans-77.1-7.4176-76.6176.1-1300114L364 R365 N366L364-Q368 WeakPolarHBondContact O-CB 3.4Å; L364-Q368 WeakPolarHBondContact O-CG 3.41Å; L364-Q368 PolarHBondContact O-N 3.41Å; R365-Q368 PolarHBondContact O-N 2.79Å; N366-Q368 VanDerWaalsContact C-N 3.3Å
369Q49.5Very low58.6Low130 Ų130121.7 Ų121.761%0.60766%0.659SS**SBendtrans-90.4117.4171.5-75-177.61300110.1R365 N366 V367 T371R365-Q369 PolarHBondContact O-N 3.26Å; N366-Q369 PolarHBondContact O-N 3.28Å; V367-Q369 VanDerWaalsContact C-N 3.27Å; V367-Q369 PolarHBondContact O-N 2.86Å; Q369-T371 PolarHBondContact O-N 2.94Å
370P47.1Very low56.4Low125 Ų125120.7 Ų120.781%0.81267%0.672SS**  trans-74.591.9-176.829.3-32000110.2Q372P370-Q372 PolarHBondContact O-N 3.41Å
371T45.5Very low54.6Low129 Ų129122.3 Ų122.379%0.79168%0.681SS**  trans-77.3108168.950.60000109.4Q369 A373Q369-T371 PolarHBondContact O-N 2.94Å; T371-A373 PolarHBondContact O-N 2.9Å
372Q38Very low53.2Low181 Ų181121.9 Ų121.985%0.84669%0.685SS**  trans-46107.1168-65.2172-600110P370 Q374P370-Q372 PolarHBondContact O-N 3.41Å; Q372-Q374 PolarHBondContact O-N 3.34Å
373A42.8Very low52Low93 Ų93126 Ų12677%0.76971%0.711SS**  trans-69.3100.1173.800000109.1T371 T375T371-A373 PolarHBondContact O-N 2.9Å; A373-T375 PolarHBondContact O-N 2.9Å
374Q34.2Very low50.7Low181 Ų181131.5 Ų131.585%0.84673%0.726SS**  trans-67.4107.1160.7-69.1179.10.100107.7Q372 P376Q372-Q374 PolarHBondContact O-N 3.34Å; Q374-P376 WeakPolarHBondContact O-CD 3.48Å
375T33.5Very low49.6Very low127 Ų127131.4 Ų131.478%0.77972%0.723SS**  trans-73.7119.7173.943.30000110.4A373A373-T375 PolarHBondContact O-N 2.9Å
376P39.4Very low48.9Very low123 Ų123130.4 Ų130.480%0.79973%0.725SS**  trans-79.4120.2168-321.4000109.3Q374Q374-P376 WeakPolarHBondContact O-CD 3.48Å
377S30.7Very low49.1Very low118 Ų118130.5 Ų130.583%0.82572%0.724SS**  trans-77.1115.5175.449.50000111.6
378I36.1Very low49.3Very low161 Ų161130.2 Ų130.283%0.82672%0.715SS**  trans-136.4140.3163.1-61.4-178.9000107.6
379P40.3Very low50.1Low109 Ų109128.2 Ų128.271%0.70870%0.704SS**  trans-97.3149.5-143.836-32.9000116.5
380S41.5Very low51.4Low108 Ų108128.6 Ų128.676%0.75570%0.704SS**  trans37.294.2146.564.50000119.7
381D48.3Very low53Low112 Ų112127.5 Ų127.560%0.59969%0.688SS**  trans-144.480.3137.9-166.412.4000108.1S383D381-S383 VanDerWaalsContact C-N 3.31Å; D381-S383 PolarHBondContact O-N 2.86Å
382D56.9Low54.6Low121 Ų121126.2 Ų126.265%0.64768%0.675SS**Hα-helixtrans-68.5-22-154.9-122.9-11.1000114.5
383S59.7Low56.7Low106 Ų106124.9 Ų124.974%0.74166%0.663SS**Hα-helixtrans-83.9-30.9-171.2-58.60000114.1D381D381-S383 VanDerWaalsContact C-N 3.31Å; D381-S383 PolarHBondContact O-N 2.86Å
384R58.3Low58.6Low194 Ų194125.7 Ų125.773%0.73265%0.652SS**Hα-helixtrans-82.5-38.6176.8-87.3179.3148.8177.2-7112.3E386 L387 E388R384-E386 VanDerWaalsContact C-N 3.32Å; R384-E386 PolarHBondContact O-N 2.84Å; R384-L387 PolarHBondContact O-N 3.08Å; R384-E388 PolarHBondContact O-N 2.87Å; R384-E388 VanDerWaalsContact O-N 3.08Å
385H56.7Low60.9Low105 Ų105120.7 Ų120.749%0.48663%0.631SS.*Hα-helixtrans-65-32.8-179.4-105-66.4000113.1K389H385-K389 VanDerWaalsContact O-CB 3.28Å; H385-K389 WeakPolarHBondContact O-CB 3.3Å; H385-K389 WeakPolarHBondContact O-CG 3.43Å; H385-K389 PolarHBondContact O-N 2.82Å
386E66.4Low63.2Low134 Ų134121.8 Ų121.863%0.62662%0.622SS**Hα-helixtrans-67.7-40.4174.8-78.8-158.2152.300112.7R384 K389 K390R384-E386 VanDerWaalsContact C-N 3.32Å; R384-E386 PolarHBondContact O-N 2.84Å; E386-K389 PolarHBondContact O-N 2.96Å; E386-K390 WeakPolarHBondContact O-CB 3.49Å; E386-K390 PolarHBondContact O-N 3.27Å
387L75.1Confident65.3Low107 Ų107122.1 Ų122.156%0.5661%0.613SS**Hα-helixtrans-66.5-44.4178.2-169.271000111R384 K390 Q391R384-L387 PolarHBondContact O-N 3.08Å; L387-K390 PolarHBondContact O-N 2.72Å; L387-Q391 WeakPolarHBondContact O-CG 3.13Å; L387-Q391 PolarHBondContact O-N 3.21Å
388E75.1Confident68Low115 Ų115125.7 Ų125.754%0.53761%0.608SS.*Hα-helixtrans-62.8-42.7174.2-75-177.3176.500111.7R384 K390 Q391 L392R384-E388 PolarHBondContact O-N 2.87Å; R384-E388 VanDerWaalsContact O-N 3.08Å; E388-K390 VanDerWaalsContact C-N 3.28Å; E388-K390 PolarHBondContact O-N 3.46Å; E388-Q391 PolarHBondContact O-N 3.5Å; E388-L392 WeakPolarHBondContact O-CB 3.05Å; E388-L392 PolarHBondContact O-N 3.12Å
389K76.3Confident70.4Confident113 Ų113124.5 Ų124.549%0.49160%0.597SS.*Hα-helixtrans-62.3-35.6174.3-79.5173.5-179.1171.80112.1H385 E386 R393H385-K389 VanDerWaalsContact O-CB 3.28Å; H385-K389 WeakPolarHBondContact O-CB 3.3Å; H385-K389 WeakPolarHBondContact O-CG 3.43Å; H385-K389 PolarHBondContact O-N 2.82Å; E386-K389 PolarHBondContact O-N 2.96Å; K389-R393 WeakPolarHBondContact O-CB 3.23Å; K389-R393 PolarHBondContact O-N 2.92Å
390K77.5Confident72.5Confident139 Ų139123.4 Ų123.460%0.60458%0.583SS**Hα-helixtrans-71.5-42.2177-163.5175.6-176.4178.30111.3E386 L387 E388 R393 M394E386-K390 WeakPolarHBondContact O-CB 3.49Å; E386-K390 PolarHBondContact O-N 3.27Å; L387-K390 PolarHBondContact O-N 2.72Å; E388-K390 VanDerWaalsContact C-N 3.28Å; E388-K390 PolarHBondContact O-N 3.46Å; K390-R393 PolarHBondContact O-N 2.92Å; K390-M394 WeakPolarHBondContact O-CG 3.34Å; K390-M394 PolarHBondContact O-N 3.2Å
391Q80.1Confident74.6Confident101 Ų101120.9 Ų120.947%0.47257%0.569SS.*Hα-helixtrans-62.7-46.5172.6-75.3179.6-7.400111.5L387 E388 R393 M394 D395L387-Q391 WeakPolarHBondContact O-CG 3.13Å; L387-Q391 PolarHBondContact O-N 3.21Å; E388-Q391 PolarHBondContact O-N 3.5Å; Q391-R393 VanDerWaalsContact C-N 3.3Å; Q391-R393 PolarHBondContact O-N 3.4Å; Q391-M394 PolarHBondContact O-N 2.93Å; Q391-M394 VanDerWaalsContact O-N 3.17Å; Q391-D395 WeakPolarHBondContact O-CB 3.38Å; Q391-D395 PolarHBondContact O-N 3.15Å
392L80.4Confident76.6Confident102 Ų102118 Ų11853%0.53456%0.561SS.*Hα-helixtrans-61-40.1177.2-165.871.3000111.1E388 D395 Y396E388-L392 WeakPolarHBondContact O-CB 3.05Å; E388-L392 PolarHBondContact O-N 3.12Å; L392-D395 PolarHBondContact O-N 2.82Å; L392-Y396 HydrophobicContact CD1-CD2 4.5Å; L392-Y396 HydrophobicContact CD1-CE2 4.4Å; L392-Y396 HydrophobicContact CD2-CE2 4.48Å; L392-Y396 HydrophobicContact CG-CD2 4.03Å; L392-Y396 HydrophobicContact CG-CE2 4.13Å; L392-Y396 WeakPolarHBondContact O-CB 3.47Å; L392-Y396 VanDerWaalsContact O-CD2 3.32Å; L392-Y396 WeakPolarHBondContact O-CD2 3.42Å; L392-Y396 PolarHBondContact O-N 2.98Å
393R80.8Confident78Confident153 Ų153116.4 Ų116.458%0.57755%0.552SS**Hα-helixtrans-61.2-48.2172.5-93.5-175.2-82.8-107.83.8112.5K389 K390 Q391 D395 Y396 E397K389-R393 WeakPolarHBondContact O-CB 3.23Å; K389-R393 PolarHBondContact O-N 2.92Å; K390-R393 PolarHBondContact O-N 2.92Å; Q391-R393 VanDerWaalsContact C-N 3.3Å; Q391-R393 PolarHBondContact O-N 3.4Å; R393-D395 VanDerWaalsContact C-N 3.31Å; R393-D395 PolarHBondContact O-N 3.05Å; R393-Y396 WeakPolarHBondContact O-CB 3.28Å; R393-Y396 PolarHBondContact O-N 3.26Å; R393-E397 WeakPolarHBondContact O-CG 3.48Å; R393-E397 PolarHBondContact O-N 3.07Å
394M83.1Confident79.3Confident111 Ų111117.5 Ų117.555%0.54755%0.545SS..Hα-helixtrans-62-39.8176.6-68.8-168-38.500112.1K390 Q391 Y396 E397 R398K390-M394 WeakPolarHBondContact O-CG 3.34Å; K390-M394 PolarHBondContact O-N 3.2Å; Q391-M394 PolarHBondContact O-N 2.93Å; Q391-M394 VanDerWaalsContact O-N 3.17Å; M394-Y396 VanDerWaalsContact C-N 3.35Å; M394-E397 PolarHBondContact O-N 2.95Å; M394-R398 WeakPolarHBondContact O-CB 3.35Å; M394-R398 PolarHBondContact O-N 3.09Å
395D83.4Confident80.7Confident76 Ų76112.4 Ų112.441%0.40653%0.529SS..Hα-helixtrans-66.6-37.3175.8-81.5-12.7000111.8Q391 L392 R393 K399Q391-D395 WeakPolarHBondContact O-CB 3.38Å; Q391-D395 PolarHBondContact O-N 3.15Å; L392-D395 PolarHBondContact O-N 2.82Å; R393-D395 VanDerWaalsContact C-N 3.31Å; R393-D395 PolarHBondContact O-N 3.05Å; D395-K399 VanDerWaalsContact O-CB 3.31Å; D395-K399 WeakPolarHBondContact O-CB 3.38Å; D395-K399 VanDerWaalsContact O-CG 3.23Å; D395-K399 WeakPolarHBondContact O-CG 3.5Å; D395-K399 PolarHBondContact O-N 2.91Å
396Y80.5Confident82.1Confident149 Ų149114 Ų11458%0.58454%0.537SS*.Hα-helixtrans-64.5-47172.2-100.8-79.2000111.4L392 R393 M394 R398 K399 M400L392-Y396 HydrophobicContact CD1-CD2 4.5Å; L392-Y396 HydrophobicContact CD1-CE2 4.4Å; L392-Y396 HydrophobicContact CD2-CE2 4.48Å; L392-Y396 HydrophobicContact CG-CD2 4.03Å; L392-Y396 HydrophobicContact CG-CE2 4.13Å; L392-Y396 WeakPolarHBondContact O-CB 3.47Å; L392-Y396 VanDerWaalsContact O-CD2 3.32Å; L392-Y396 WeakPolarHBondContact O-CD2 3.42Å; L392-Y396 PolarHBondContact O-N 2.98Å; R393-Y396 WeakPolarHBondContact O-CB 3.28Å; R393-Y396 PolarHBondContact O-N 3.26Å; M394-Y396 VanDerWaalsContact C-N 3.35Å; Y396-R398 VanDerWaalsContact C-N 3.32Å; Y396-R398 PolarHBondContact O-N 3.17Å; Y396-K399 PolarHBondContact O-N 3.42Å; Y396-M400 VanDerWaalsContact O-CB 3.32Å; Y396-M400 WeakPolarHBondContact O-CB 3.22Å; Y396-M400 VanDerWaalsContact O-CG 3.27Å; Y396-M400 WeakPolarHBondContact O-CG 3.24Å; Y396-M400 PolarHBondContact O-N 3.22Å
397E84.7Confident83.2Confident131 Ų131113.5 Ų113.561%0.61253%0.533SS*.Hα-helixtrans-60.7-41.8176.6-75.2171.1-173.900111.5R393 M394 M400 A401R393-E397 WeakPolarHBondContact O-CG 3.48Å; R393-E397 PolarHBondContact O-N 3.07Å; M394-E397 PolarHBondContact O-N 2.95Å; E397-M400 PolarHBondContact O-N 3.2Å; E397-A401 WeakPolarHBondContact O-CB 3.34Å; E397-A401 PolarHBondContact O-N 3.45Å
398R87.2Confident83.8Confident193 Ų193115.9 Ų115.973%0.72854%0.535SS*.Hα-helixtrans-65.9-43175.7-174.8-177.3-96.2168.4-8.7112.1M394 Y396 M400 A402M394-R398 WeakPolarHBondContact O-CB 3.35Å; M394-R398 PolarHBondContact O-N 3.09Å; Y396-R398 VanDerWaalsContact C-N 3.32Å; Y396-R398 PolarHBondContact O-N 3.17Å; R398-M400 VanDerWaalsContact C-N 3.35Å; R398-A402 WeakPolarHBondContact O-CB 3.41Å; R398-A402 PolarHBondContact O-N 3.23Å
399K86.7Confident84.5Confident135 Ų135114.9 Ų114.959%0.58753%0.531SS*.Hα-helixtrans-65-39.9174.8-77.1174.2-177.6175.30111.4D395 Y396 A402 I403D395-K399 VanDerWaalsContact O-CB 3.31Å; D395-K399 WeakPolarHBondContact O-CB 3.38Å; D395-K399 VanDerWaalsContact O-CG 3.23Å; D395-K399 WeakPolarHBondContact O-CG 3.5Å; D395-K399 PolarHBondContact O-N 2.91Å; Y396-K399 PolarHBondContact O-N 3.42Å; K399-A402 PolarHBondContact O-N 3.08Å; K399-I403 WeakPolarHBondContact O-CB 3.39Å; K399-I403 WeakPolarHBondContact O-CD1 3.2Å; K399-I403 WeakPolarHBondContact O-CG1 3.46Å; K399-I403 PolarHBondContact O-N 3Å
400M83.5Confident85Confident86 Ų86115.7 Ų115.742%0.42454%0.537SS..Hα-helixtrans-65.3-45.3177.7-76.9-49.1-4000111.6Y396 E397 R398 A402 I403 E404Y396-M400 VanDerWaalsContact O-CB 3.32Å; Y396-M400 WeakPolarHBondContact O-CB 3.22Å; Y396-M400 VanDerWaalsContact O-CG 3.27Å; Y396-M400 WeakPolarHBondContact O-CG 3.24Å; Y396-M400 PolarHBondContact O-N 3.22Å; E397-M400 PolarHBondContact O-N 3.2Å; R398-M400 VanDerWaalsContact C-N 3.35Å; M400-A402 VanDerWaalsContact C-N 3.3Å; M400-A402 PolarHBondContact O-N 3.13Å; M400-I403 HydrophobicContact CE-CB 4.5Å; M400-I403 HydrophobicContact CE-CG2 4.47Å; M400-I403 PolarHBondContact O-N 2.92Å; M400-I403 HydrophobicContact SD-CD1 4.31Å; M400-E404 WeakPolarHBondContact O-CG 3.45Å; M400-E404 PolarHBondContact O-N 3.19Å
401A87Confident85.5Confident55 Ų55113.1 Ų113.146%0.45553%0.527SS..Hα-helixtrans-61.1-38.917400000112.2E397 E404 E405E397-A401 WeakPolarHBondContact O-CB 3.34Å; E397-A401 PolarHBondContact O-N 3.45Å; A401-E404 PolarHBondContact O-N 2.85Å; A401-E405 WeakPolarHBondContact O-CB 3.45Å; A401-E405 PolarHBondContact O-N 3.01Å
402A89.1Confident85.9Confident52 Ų52112.8 Ų112.843%0.4353%0.527SS..Hα-helixtrans-66.3-39.1175.100000112.5R398 K399 M400 E405 Q406R398-A402 WeakPolarHBondContact O-CB 3.41Å; R398-A402 PolarHBondContact O-N 3.23Å; K399-A402 PolarHBondContact O-N 3.08Å; M400-A402 VanDerWaalsContact C-N 3.3Å; M400-A402 PolarHBondContact O-N 3.13Å; A402-E405 PolarHBondContact O-N 3.01Å; A402-Q406 WeakPolarHBondContact O-CB 3.5Å; A402-Q406 WeakPolarHBondContact O-CG 3.41Å; A402-Q406 PolarHBondContact O-N 3.4Å
403I87.3Confident86.1Confident88 Ų88111.4 Ų111.445%0.45152%0.523SS..Hα-helixtrans-67-41.8175.2-70.9164.4000110.6K399 M400 Q406 F407K399-I403 WeakPolarHBondContact O-CB 3.39Å; K399-I403 WeakPolarHBondContact O-CD1 3.2Å; K399-I403 WeakPolarHBondContact O-CG1 3.46Å; K399-I403 PolarHBondContact O-N 3Å; M400-I403 HydrophobicContact CE-CB 4.5Å; M400-I403 HydrophobicContact CE-CG2 4.47Å; M400-I403 PolarHBondContact O-N 2.92Å; M400-I403 HydrophobicContact SD-CD1 4.31Å; I403-Q406 PolarHBondContact O-N 2.79Å; I403-F407 VanDerWaalsContact O-CB 3.25Å; I403-F407 WeakPolarHBondContact O-CB 3.26Å; I403-F407 PolarHBondContact O-N 3.23Å
404E85.4Confident86.5Confident129 Ų129109.1 Ų109.160%0.60352%0.517SS*.Hα-helixtrans-62.5-42175.7-76.7177.8177.600111.7M400 A401 F407 R408M400-E404 WeakPolarHBondContact O-CG 3.45Å; M400-E404 PolarHBondContact O-N 3.19Å; A401-E404 PolarHBondContact O-N 2.85Å; E404-F407 PolarHBondContact O-N 3.41Å; E404-R408 VanDerWaalsContact O-CB 3.3Å; E404-R408 WeakPolarHBondContact O-CB 3.29Å; E404-R408 PolarHBondContact O-N 3.48Å
405E88.9Confident86.7Confident86 Ų86106.1 Ų106.140%0.40251%0.507SS..Hα-helixtrans-68.5-41.1176.4-17359.7-160.200111.9A401 A402 F407 R408 M409A401-E405 WeakPolarHBondContact O-CB 3.45Å; A401-E405 PolarHBondContact O-N 3.01Å; A402-E405 PolarHBondContact O-N 3.01Å; E405-F407 VanDerWaalsContact C-N 3.35Å; E405-R408 PolarHBondContact O-N 3.32Å; E405-M409 WeakPolarHBondContact O-CB 3.37Å; E405-M409 VanDerWaalsContact O-CG 3.31Å; E405-M409 WeakPolarHBondContact O-CG 3.04Å; E405-M409 PolarHBondContact O-N 3.3Å; E405-M409 WeakPolarHBondContact OE1-CE 3.47Å
406Q85.8Confident87Confident139 Ų139110.3 Ų110.365%0.6552%0.518SS*.Hα-helixtrans-59.8-46.1171.9-81.2-176.5-15.200111.4A402 I403 R408 M409 E410A402-Q406 WeakPolarHBondContact O-CB 3.5Å; A402-Q406 WeakPolarHBondContact O-CG 3.41Å; A402-Q406 PolarHBondContact O-N 3.4Å; I403-Q406 PolarHBondContact O-N 2.79Å; Q406-R408 VanDerWaalsContact C-N 3.32Å; Q406-R408 PolarHBondContact O-N 3.41Å; Q406-M409 PolarHBondContact O-N 2.97Å; Q406-E410 VanDerWaalsContact O-CB 3.27Å; Q406-E410 WeakPolarHBondContact O-CB 3.4Å; Q406-E410 PolarHBondContact O-N 2.77Å
407F88.5Confident87.2Confident123 Ų123108.2 Ų108.254%0.53952%0.516SS..Hα-helixtrans-62.9-41177.4-176.6-102.1000111.2I403 E404 E405 E410 Q411I403-F407 VanDerWaalsContact O-CB 3.25Å; I403-F407 WeakPolarHBondContact O-CB 3.26Å; I403-F407 PolarHBondContact O-N 3.23Å; E404-F407 PolarHBondContact O-N 3.41Å; E405-F407 VanDerWaalsContact C-N 3.35Å; F407-E410 CarbonylContact O-C 3.59Å; F407-E410 PolarHBondContact O-N 3.08Å; F407-Q411 HydrophobicContact CD1-CG 4.13Å; F407-Q411 HydrophobicContact CE1-CG 3.82Å; F407-Q411 HydrophobicContact CZ-CG 4.09Å; F407-Q411 VanDerWaalsContact O-CG 3.26Å; F407-Q411 WeakPolarHBondContact O-CG 3.26Å; F407-Q411 PolarHBondContact O-N 3.24Å
408R89.4Confident87.3Confident158 Ų158106.9 Ų106.960%0.59651%0.51SS*.Hα-helixtrans-62.5-45.7175.4-173.5-177.7-176163.72.8111.6E404 E405 Q406 E410 Q411 I412E404-R408 VanDerWaalsContact O-CB 3.3Å; E404-R408 WeakPolarHBondContact O-CB 3.29Å; E404-R408 PolarHBondContact O-N 3.48Å; E405-R408 PolarHBondContact O-N 3.32Å; Q406-R408 VanDerWaalsContact C-N 3.32Å; Q406-R408 PolarHBondContact O-N 3.41Å; R408-E410 VanDerWaalsContact C-N 3.3Å; R408-E410 PolarHBondContact O-N 2.69Å; R408-Q411 PolarHBondContact O-N 2.82Å; R408-I412 HydrophobicContact CG-CD1 4.24Å; R408-I412 VanDerWaalsContact O-CG1 3.3Å; R408-I412 WeakPolarHBondContact O-CG1 3.5Å; R408-I412 PolarHBondContact O-N 3.12Å
409M88.4Confident87.3Confident94 Ų94104.1 Ų104.146%0.46350%0.503SS..Hα-helixtrans-62.8-40.1175.3-73-66.4163.700111.1E405 Q406 I412 T413E405-M409 WeakPolarHBondContact O-CB 3.37Å; E405-M409 VanDerWaalsContact O-CG 3.31Å; E405-M409 WeakPolarHBondContact O-CG 3.04Å; E405-M409 PolarHBondContact O-N 3.3Å; E405-M409 WeakPolarHBondContact OE1-CE 3.47Å; Q406-M409 PolarHBondContact O-N 2.97Å; M409-I412 PolarHBondContact O-N 2.97Å; M409-I412 HydrophobicContact SD-CD1 4.49Å; M409-T413 WeakPolarHBondContact O-CG2 3.47Å; M409-T413 PolarHBondContact O-N 3.47Å; M409-T413 PolarHBondContact O-OG1 3.23Å; M409-T413 VanDerWaalsContact O-OG1 3.08Å
410E87Confident87.3Confident130 Ų130101.5 Ų101.561%0.60749%0.493SS*.Hα-helixtrans-66.2-35.7176-165.8164.3-161.500112.2Q406 F407 R408 T413 K414Q406-E410 VanDerWaalsContact O-CB 3.27Å; Q406-E410 WeakPolarHBondContact O-CB 3.4Å; Q406-E410 PolarHBondContact O-N 2.77Å; F407-E410 CarbonylContact O-C 3.59Å; F407-E410 PolarHBondContact O-N 3.08Å; R408-E410 VanDerWaalsContact C-N 3.3Å; R408-E410 PolarHBondContact O-N 2.69Å; E410-T413 VanDerWaalsContact CA-OG1 3.3Å; E410-T413 WeakPolarHBondContact CA-OG1 3.03Å; E410-T413 PolarHBondContact O-OG1 2.97Å; E410-K414 WeakPolarHBondContact O-CB 3.32Å; E410-K414 PolarHBondContact O-N 3.4Å
411Q87.4Confident87.3Confident85 Ų85103.2 Ų103.240%0.39750%0.503SS..Hα-helixtrans-68-39.6171.7-70.2-65.2-26.600111.9F407 R408 S415F407-Q411 HydrophobicContact CD1-CG 4.13Å; F407-Q411 HydrophobicContact CE1-CG 3.82Å; F407-Q411 HydrophobicContact CZ-CG 4.09Å; F407-Q411 VanDerWaalsContact O-CG 3.26Å; F407-Q411 WeakPolarHBondContact O-CG 3.26Å; F407-Q411 PolarHBondContact O-N 3.24Å; R408-Q411 PolarHBondContact O-N 2.82Å; Q411-S415 WeakPolarHBondContact O-CB 3.38Å; Q411-S415 PolarHBondContact O-N 3.37Å
412I89.1Confident87.3Confident93 Ų93103.5 Ų103.548%0.47750%0.502SS..Hα-helixtrans-66.4-46.3176.5-68.5165.9000110.5R408 M409 S415 R416R408-I412 HydrophobicContact CG-CD1 4.24Å; R408-I412 VanDerWaalsContact O-CG1 3.3Å; R408-I412 WeakPolarHBondContact O-CG1 3.5Å; R408-I412 PolarHBondContact O-N 3.12Å; M409-I412 PolarHBondContact O-N 2.97Å; M409-I412 HydrophobicContact SD-CD1 4.49Å; I412-S415 PolarHBondContact O-N 2.9Å; I412-R416 WeakPolarHBondContact O-CB 3.21Å; I412-R416 PolarHBondContact O-N 2.72Å
413T85.8Confident87.1Confident73 Ų73109.6 Ų109.645%0.44851%0.514SS..Hα-helixtrans-66.1-41.7177.255.30000110.9M409 E410 R416 L417M409-T413 WeakPolarHBondContact O-CG2 3.47Å; M409-T413 PolarHBondContact O-N 3.47Å; M409-T413 PolarHBondContact O-OG1 3.23Å; M409-T413 VanDerWaalsContact O-OG1 3.08Å; E410-T413 VanDerWaalsContact CA-OG1 3.3Å; E410-T413 WeakPolarHBondContact CA-OG1 3.03Å; E410-T413 PolarHBondContact O-OG1 2.97Å; T413-R416 WeakPolarHBondContact O-CB 3.19Å; T413-R416 PolarHBondContact O-N 3.1Å; T413-L417 WeakPolarHBondContact O-CB 3.36Å; T413-L417 VanDerWaalsContact O-CG 3.25Å; T413-L417 WeakPolarHBondContact O-CG 3.24Å; T413-L417 PolarHBondContact O-N 3.47Å
414K87.8Confident86.7Confident105 Ų105110.2 Ų110.246%0.45752%0.517SS..Hα-helixtrans-57.8-48.8172.5-179.6179.9169.7-175.90111.5E410 R416 L417 E418E410-K414 WeakPolarHBondContact O-CB 3.32Å; E410-K414 PolarHBondContact O-N 3.4Å; K414-R416 VanDerWaalsContact C-N 3.3Å; K414-R416 PolarHBondContact O-N 3.07Å; K414-L417 PolarHBondContact O-N 3.03Å; K414-E418 WeakPolarHBondContact CE-OE1 3.34Å; K414-E418 HydrophobicContact CG-CG 4.39Å; K414-E418 IonicContact NZ-OE1 2.67Å; K414-E418 WeakPolarHBondContact O-CB 2.86Å; K414-E418 VanDerWaalsContact O-CG 3.29Å; K414-E418 WeakPolarHBondContact O-CG 3.16Å; K414-E418 PolarHBondContact O-N 3.35Å
415S87.7Confident86.6Confident48 Ų48112 Ų11234%0.33652%0.518SS..Hα-helixtrans-62.3-37.6177.4-1760000112.4Q411 I412 K419Q411-S415 WeakPolarHBondContact O-CB 3.38Å; Q411-S415 PolarHBondContact O-N 3.37Å; I412-S415 PolarHBondContact O-N 2.9Å; S415-K419 WeakPolarHBondContact O-CG 3.22Å; S415-K419 PolarHBondContact O-N 3.28Å; S415-K419 VanDerWaalsContact O-N 3.07Å
416R90Very high86.3Confident165 Ų165111.1 Ų111.162%0.62352%0.517SS*.Hα-helixtrans-65.1-47.7173.9178.9-177.9170.4177.5-1.4111.4I412 T413 K414 E418 K419 E420I412-R416 WeakPolarHBondContact O-CB 3.21Å; I412-R416 PolarHBondContact O-N 2.72Å; T413-R416 WeakPolarHBondContact O-CB 3.19Å; T413-R416 PolarHBondContact O-N 3.1Å; K414-R416 VanDerWaalsContact C-N 3.3Å; K414-R416 PolarHBondContact O-N 3.07Å; R416-E418 VanDerWaalsContact C-N 3.33Å; R416-E418 PolarHBondContact O-N 3.17Å; R416-K419 WeakPolarHBondContact O-CB 3.43Å; R416-K419 PolarHBondContact O-N 3.48Å; R416-E420 IonicContact CZ-OE1 3.52Å; R416-E420 IonicContact NE-OE1 2.79Å; R416-E420 PolarHBondContact NE-OE1 3.44Å; R416-E420 IonicContact NH2-OE1 3.31Å; R416-E420 PolarHBondContact NH2-OE1 2.75Å; R416-E420 WeakPolarHBondContact O-CG 3.35Å; R416-E420 PolarHBondContact O-N 2.88Å
417L85.2Confident85.9Confident104 Ų104107.5 Ų107.555%0.54551%0.507SS..Hα-helixtrans-64-38.3178.4-73.2170.7000111.1T413 K414 E420 L421T413-L417 WeakPolarHBondContact O-CB 3.36Å; T413-L417 VanDerWaalsContact O-CG 3.25Å; T413-L417 WeakPolarHBondContact O-CG 3.24Å; T413-L417 PolarHBondContact O-N 3.47Å; K414-L417 PolarHBondContact O-N 3.03Å; L417-E420 PolarHBondContact O-N 3.34Å; L417-L421 WeakPolarHBondContact O-CB 3.41Å; L417-L421 PolarHBondContact O-N 2.86Å
418E86.3Confident85.2Confident104 Ų104108.7 Ų108.749%0.48651%0.508SS..Hα-helixtrans-63.5-39.5174-76.4173.3173.200111.7K414 R416 S422K414-E418 WeakPolarHBondContact CE-OE1 3.34Å; K414-E418 HydrophobicContact CG-CG 4.39Å; K414-E418 IonicContact NZ-OE1 2.67Å; K414-E418 WeakPolarHBondContact O-CB 2.86Å; K414-E418 VanDerWaalsContact O-CG 3.29Å; K414-E418 WeakPolarHBondContact O-CG 3.16Å; K414-E418 PolarHBondContact O-N 3.35Å; R416-E418 VanDerWaalsContact C-N 3.33Å; R416-E418 PolarHBondContact O-N 3.17Å; E418-S422 VanDerWaalsContact O-CB 3.31Å; E418-S422 WeakPolarHBondContact O-CB 3.4Å; E418-S422 PolarHBondContact O-N 2.87Å
419K87.8Confident84.5Confident134 Ų134105 Ų10558%0.58350%0.501SS*.Hα-helixtrans-67-42.3173.1-74.3171.1-177.6172.30112.3S415 R416 S422 R423S415-K419 WeakPolarHBondContact O-CG 3.22Å; S415-K419 PolarHBondContact O-N 3.28Å; S415-K419 VanDerWaalsContact O-N 3.07Å; R416-K419 WeakPolarHBondContact O-CB 3.43Å; R416-K419 PolarHBondContact O-N 3.48Å; K419-S422 PolarHBondContact O-N 3.05Å; K419-R423 WeakPolarHBondContact O-CG 3.47Å; K419-R423 PolarHBondContact O-N 3.03Å
420E86.6Confident84Confident80 Ų80107 Ų10737%0.37450%0.503SS..Hα-helixtrans-65.4-42.8175.6-74.6177.7-16900110.9R416 L417 S422 R423 L424R416-E420 IonicContact CZ-OE1 3.52Å; R416-E420 IonicContact NE-OE1 2.79Å; R416-E420 PolarHBondContact NE-OE1 3.44Å; R416-E420 IonicContact NH2-OE1 3.31Å; R416-E420 PolarHBondContact NH2-OE1 2.75Å; R416-E420 WeakPolarHBondContact O-CG 3.35Å; R416-E420 PolarHBondContact O-N 2.88Å; L417-E420 PolarHBondContact O-N 3.34Å; E420-S422 PolarHBondContact O-N 3.26Å; E420-R423 PolarHBondContact O-N 3.34Å; E420-L424 WeakPolarHBondContact O-CB 3.37Å; E420-L424 PolarHBondContact O-N 3.23Å
421L83.7Confident83.2Confident123 Ų123102.6 Ų102.664%0.64449%0.489SS*.Hα-helixtrans-61.8-42174.3-166.395.9000111.1L417 L424 R425L417-L421 WeakPolarHBondContact O-CB 3.41Å; L417-L421 PolarHBondContact O-N 2.86Å; L421-L424 PolarHBondContact O-N 3.49Å; L421-R425 WeakPolarHBondContact O-CB 3.29Å; L421-R425 PolarHBondContact O-N 3.39Å
422S86.4Confident82.2Confident61 Ų61102 Ų10243%0.42749%0.488SS..Hα-helixtrans-63.8-44.4174.7-170.60000111.5E418 K419 E420 L424 R425 D426E418-S422 VanDerWaalsContact O-CB 3.31Å; E418-S422 WeakPolarHBondContact O-CB 3.4Å; E418-S422 PolarHBondContact O-N 2.87Å; K419-S422 PolarHBondContact O-N 3.05Å; E420-S422 PolarHBondContact O-N 3.26Å; S422-L424 VanDerWaalsContact C-N 3.33Å; S422-L424 PolarHBondContact O-N 3.03Å; S422-R425 PolarHBondContact O-N 3.11Å; S422-D426 PolarHBondContact O-N 3.29Å
423R85.6Confident81Confident180 Ų18099 Ų9968%0.67948%0.479SS*.Hα-helixtrans-63.3-40.6175.9-74.6174.2-179.6178.5-0.2112.1K419 E420 S427K419-R423 WeakPolarHBondContact O-CG 3.47Å; K419-R423 PolarHBondContact O-N 3.03Å; E420-R423 PolarHBondContact O-N 3.34Å; R423-S427 WeakPolarHBondContact O-CB 3.39Å; R423-S427 PolarHBondContact O-N 2.99Å
424L78.8Confident80Confident100 Ų100103.8 Ų103.852%0.52449%0.489SS..Hα-helixtrans-66.3-44.3177.2-155.581.6000109.9E420 L421 S422 S427 Y428E420-L424 WeakPolarHBondContact O-CB 3.37Å; E420-L424 PolarHBondContact O-N 3.23Å; L421-L424 PolarHBondContact O-N 3.49Å; S422-L424 VanDerWaalsContact C-N 3.33Å; S422-L424 PolarHBondContact O-N 3.03Å; L424-S427 CarbonylContact O-C 3.53Å; L424-S427 WeakPolarHBondContact O-CA 3.34Å; L424-S427 VanDerWaalsContact O-CB 3.28Å; L424-S427 WeakPolarHBondContact O-CB 3.32Å; L424-S427 PolarHBondContact O-N 3.16Å; L424-S427 VanDerWaalsContact O-N 3.13Å; L424-Y428 HydrophobicContact CD2-CD2 4.37Å; L424-Y428 HydrophobicContact CD2-CE2 3.9Å; L424-Y428 HydrophobicContact CG-CD2 4.05Å; L424-Y428 HydrophobicContact CG-CE2 3.9Å; L424-Y428 VanDerWaalsContact O-CD2 3.25Å; L424-Y428 WeakPolarHBondContact O-CD2 3.03Å; L424-Y428 PolarHBondContact O-N 2.61Å
425R82.8Confident78.2Confident167 Ų16799.3 Ų99.363%0.6347%0.471SS*.Hα-helixtrans-58.9-48.7174.2-175.2175.4-172.7161.44.7111.5L421 S422 S427 Y428 D429L421-R425 WeakPolarHBondContact O-CB 3.29Å; L421-R425 PolarHBondContact O-N 3.39Å; S422-R425 PolarHBondContact O-N 3.11Å; R425-S427 PolarHBondContact O-N 3.07Å; R425-Y428 CarbonylContact O-C 3.55Å; R425-Y428 WeakPolarHBondContact O-CA 3.31Å; R425-Y428 WeakPolarHBondContact O-CB 3.45Å; R425-Y428 PolarHBondContact O-N 2.97Å; R425-D429 IonicContact NE-OD2 2.91Å; R425-D429 WeakPolarHBondContact O-CB 3.45Å; R425-D429 PolarHBondContact O-N 3.07Å
426D81.9Confident76.9Confident68 Ų68104 Ų10436%0.36449%0.488SS..Hα-helixtrans-61.5-34.8175.4-64.4-21000111.8S422 R430S422-D426 PolarHBondContact O-N 3.29Å; D426-R430 VanDerWaalsContact O-CB 3.24Å; D426-R430 WeakPolarHBondContact O-CB 3.35Å; D426-R430 WeakPolarHBondContact O-CG 3.43Å; D426-R430 PolarHBondContact O-N 3.07Å; D426-R430 PolarHBondContact O-NE 2.92Å
427S78.3Confident75.3Confident63 Ų63102.9 Ų102.944%0.44149%0.494SS..Hα-helixtrans-65.8-41.9173.4-173.80000111.7R423 L424 R425 A431R423-S427 WeakPolarHBondContact O-CB 3.39Å; R423-S427 PolarHBondContact O-N 2.99Å; L424-S427 CarbonylContact O-C 3.53Å; L424-S427 WeakPolarHBondContact O-CA 3.34Å; L424-S427 VanDerWaalsContact O-CB 3.28Å; L424-S427 WeakPolarHBondContact O-CB 3.32Å; L424-S427 PolarHBondContact O-N 3.16Å; L424-S427 VanDerWaalsContact O-N 3.13Å; R425-S427 PolarHBondContact O-N 3.07Å; S427-A431 WeakPolarHBondContact O-CB 3.44Å; S427-A431 PolarHBondContact O-N 2.8Å
428Y72.3Confident73.5Confident147 Ų147103 Ų10358%0.57650%0.495SS*.Hα-helixtrans-66.7-47.8174.7-89.5-74000111.3L424 R425 R430 A431 I432L424-Y428 HydrophobicContact CD2-CD2 4.37Å; L424-Y428 HydrophobicContact CD2-CE2 3.9Å; L424-Y428 HydrophobicContact CG-CD2 4.05Å; L424-Y428 HydrophobicContact CG-CE2 3.9Å; L424-Y428 VanDerWaalsContact O-CD2 3.25Å; L424-Y428 WeakPolarHBondContact O-CD2 3.03Å; L424-Y428 PolarHBondContact O-N 2.61Å; R425-Y428 CarbonylContact O-C 3.55Å; R425-Y428 WeakPolarHBondContact O-CA 3.31Å; R425-Y428 WeakPolarHBondContact O-CB 3.45Å; R425-Y428 PolarHBondContact O-N 2.97Å; Y428-R430 VanDerWaalsContact C-N 3.28Å; Y428-R430 PolarHBondContact O-N 2.95Å; Y428-A431 CarbonylContact O-C 3.56Å; Y428-A431 WeakPolarHBondContact O-CA 3.44Å; Y428-A431 WeakPolarHBondContact O-CB 3.35Å; Y428-A431 PolarHBondContact O-N 3.43Å; Y428-I432 WeakPolarHBondContact O-CB 3.33Å; Y428-I432 VanDerWaalsContact O-CG1 3.26Å; Y428-I432 WeakPolarHBondContact O-CG1 3.49Å; Y428-I432 PolarHBondContact O-N 3.26Å
429D76.6Confident72Confident82 Ų82106.5 Ų106.544%0.43951%0.512SS..Hα-helixtrans-62.4-37177.8-68.1-19.7000110.7R425 A431 G433R425-D429 IonicContact NE-OD2 2.91Å; R425-D429 WeakPolarHBondContact O-CB 3.45Å; R425-D429 PolarHBondContact O-N 3.07Å; D429-A431 VanDerWaalsContact C-N 3.34Å; D429-G433 PolarHBondContact O-N 3.01Å
430R77.2Confident70.2Confident135 Ų135102.4 Ų102.451%0.50950%0.503SS..Hα-helixtrans-69-27169.9-76.4-175.8-69.8-101.7-2.4113.8D426 Y428 R434D426-R430 VanDerWaalsContact O-CB 3.24Å; D426-R430 WeakPolarHBondContact O-CB 3.35Å; D426-R430 WeakPolarHBondContact O-CG 3.43Å; D426-R430 PolarHBondContact O-N 3.07Å; D426-R430 PolarHBondContact O-NE 2.92Å; Y428-R430 VanDerWaalsContact C-N 3.28Å; Y428-R430 PolarHBondContact O-N 2.95Å; R430-R434 WeakPolarHBondContact O-CB 3.44Å; R430-R434 VanDerWaalsContact O-CG 3.28Å; R430-R434 WeakPolarHBondContact O-CG 3.42Å; R430-R434 PolarHBondContact O-N 2.9Å; R430-R434 PolarHBondContact O-NE 3.04Å
431A69.3Low68.4Low37 Ų3799.2 Ų99.231%0.30649%0.492SS..Hα-helixtrans-81-39.8175.700000111.1S427 Y428 D429 R434 A435S427-A431 WeakPolarHBondContact O-CB 3.44Å; S427-A431 PolarHBondContact O-N 2.8Å; Y428-A431 CarbonylContact O-C 3.56Å; Y428-A431 WeakPolarHBondContact O-CA 3.44Å; Y428-A431 WeakPolarHBondContact O-CB 3.35Å; Y428-A431 PolarHBondContact O-N 3.43Å; D429-A431 VanDerWaalsContact C-N 3.34Å; A431-R434 CarbonylContact O-C 3.53Å; A431-R434 WeakPolarHBondContact O-CB 3.33Å; A431-R434 PolarHBondContact O-N 2.7Å; A431-A435 WeakPolarHBondContact O-CB 3.33Å; A431-A435 PolarHBondContact O-N 2.8Å
432I66.4Low66.8Low74 Ų7499.6 Ų99.638%0.37949%0.493SS..Hα-helixtrans-65.4-51.5174.2-67.9166.5000109.1Y428 R434 A435 E436Y428-I432 WeakPolarHBondContact O-CB 3.33Å; Y428-I432 VanDerWaalsContact O-CG1 3.26Å; Y428-I432 WeakPolarHBondContact O-CG1 3.49Å; Y428-I432 PolarHBondContact O-N 3.26Å; I432-R434 PolarHBondContact O-N 3.39Å; I432-R434 VanDerWaalsContact O-N 3.1Å; I432-A435 CarbonylContact O-C 3.6Å; I432-A435 WeakPolarHBondContact O-CA 3.49Å; I432-A435 PolarHBondContact O-N 3.09Å; I432-E436 HydrophobicContact CG2-CG 3.84Å; I432-E436 WeakPolarHBondContact CG2-OE1 3.36Å; I432-E436 WeakPolarHBondContact O-CB 3.41Å; I432-E436 WeakPolarHBondContact O-CG 3.42Å; I432-E436 PolarHBondContact O-N 3.41Å
433G65.2Low65Low28 Ų2896.8 Ų96.829%0.28947%0.474SS..Hα-helixtrans-61.2-23.4175.400000113.7D429 N437D429-G433 PolarHBondContact O-N 3.01Å; G433-N437 PolarHBondContact O-ND2 2.92Å
434R63.4Low63.4Low175 Ų17591 Ų9166%0.6646%0.461SS*.Hα-helixtrans-79.8-28.6168.7-81.6-175-91.2-152.81113.3R430 A431 I432R430-R434 WeakPolarHBondContact O-CB 3.44Å; R430-R434 VanDerWaalsContact O-CG 3.28Å; R430-R434 WeakPolarHBondContact O-CG 3.42Å; R430-R434 PolarHBondContact O-N 2.9Å; R430-R434 PolarHBondContact O-NE 3.04Å; A431-R434 CarbonylContact O-C 3.53Å; A431-R434 WeakPolarHBondContact O-CB 3.33Å; A431-R434 PolarHBondContact O-N 2.7Å; I432-R434 PolarHBondContact O-N 3.39Å; I432-R434 VanDerWaalsContact O-N 3.1Å
435A51.6Low62.2Low10 Ų1091 Ų918%0.08346%0.461CS..Hα-helixtrans-89.3-21.2177.500000114A431 I432 N438A431-A435 WeakPolarHBondContact O-CB 3.33Å; A431-A435 PolarHBondContact O-N 2.8Å; I432-A435 CarbonylContact O-C 3.6Å; I432-A435 WeakPolarHBondContact O-CA 3.49Å; I432-A435 PolarHBondContact O-N 3.09Å; A435-N438 CarbonylContact C-O 3.5Å; A435-N438 CarbonylContact O-C 3.57Å
436E58.7Low60.7Low147 Ų14787.1 Ų87.169%0.68745%0.45SS*.Hα-helixtrans-80-34.2173.8-74.3178.2165.800110.5I432 N438I432-E436 HydrophobicContact CG2-CG 3.84Å; I432-E436 WeakPolarHBondContact CG2-OE1 3.36Å; I432-E436 WeakPolarHBondContact O-CB 3.41Å; I432-E436 WeakPolarHBondContact O-CG 3.42Å; I432-E436 PolarHBondContact O-N 3.41Å; E436-N438 PolarHBondContact O-N 3.42Å
437N56.7Low59Low141 Ų14184.6 Ų84.675%0.75444%0.438SS*.SBendtrans-77.1-6.5172.6-73.7-44.9000113.5G433G433-N437 PolarHBondContact O-ND2 2.92Å
438N48.3Very low57.9Low107 Ų10785.5 Ų85.557%0.57245%0.449SS*.  trans-146.499.2175.2-85.2-30.4000107.4A435 E436 A440 G441A435-N438 CarbonylContact C-O 3.5Å; A435-N438 CarbonylContact O-C 3.57Å; E436-N438 PolarHBondContact O-N 3.42Å; N438-A440 HydrophobicContact CB-CB 4.43Å; N438-A440 CarbonylContact O-C 3.59Å; N438-A440 PolarHBondContact O-N 2.77Å; N438-G441 PolarHBondContact O-N 2.97Å
439E54.4Low57.1Low178 Ų17886.8 Ų86.883%0.83246%0.461SS*.THydrogen-bonded Turntrans-48.6-21.9170.3-70.2-175.1150.100112.4G441E439-G441 VanDerWaalsContact C-N 3.26Å; E439-G441 PolarHBondContact O-N 3.33Å
440A50.2Low56.1Low48 Ų4886.1 Ų86.140%0.39746%0.459SS..Hα-helixtrans-62.3-15.3168.800000116.1N438 S444N438-A440 HydrophobicContact CB-CB 4.43Å; N438-A440 CarbonylContact O-C 3.59Å; N438-A440 PolarHBondContact O-N 2.77Å; A440-S444 VanDerWaalsContact O-CB 3.23Å; A440-S444 WeakPolarHBondContact O-CB 3.24Å; A440-S444 PolarHBondContact O-N 3.05Å
441G47.8Very low55.2Low13 Ų1383.2 Ų83.213%0.13447%0.472CS..Hα-helixtrans-81.1-39.1-171.300000115N438 E439 A443 S444 N445N438-G441 PolarHBondContact O-N 2.97Å; E439-G441 VanDerWaalsContact C-N 3.26Å; E439-G441 PolarHBondContact O-N 3.33Å; G441-A443 VanDerWaalsContact C-N 3.32Å; G441-S444 WeakPolarHBondContact O-CB 3.47Å; G441-S444 PolarHBondContact O-N 2.84Å; G441-S444 VanDerWaalsContact O-N 3.16Å; G441-N445 PolarHBondContact O-N 3.4Å
442L51.7Low54.4Low130 Ų13084 Ų8468%0.68147%0.47SS*.Hα-helixtrans-63.5-42.7169.2-85.6142.9000110.2S444 N445 F446L442-S444 VanDerWaalsContact C-N 3.3Å; L442-S444 PolarHBondContact O-N 3.16Å; L442-N445 PolarHBondContact O-N 3.26Å; L442-F446 PolarHBondContact O-N 3.41Å
443A48.3Very low54.5Low2 Ų285.9 Ų85.92%0.01748%0.481CS..Hα-helixtrans-61.3-37.5170.500000111.8G441 A447 T454 A457 I458G441-A443 VanDerWaalsContact C-N 3.32Å; A443-A447 WeakPolarHBondContact O-CB 3.47Å; A443-A447 PolarHBondContact O-N 2.92Å; A443-T454 HydrophobicContact CB-CG2 3.94Å; A443-A457 HydrophobicContact CB-CB 4.41Å; A443-I458 HydrophobicContact CB-CD1 4.21Å; A443-I458 HydrophobicContact CB-CG1 3.94Å
444S51.3Low54.6Low58 Ų5887 Ų8741%0.40648%0.482SS..Hα-helixtrans-69.1-35.7178.5-177.10000113.4A440 G441 L442 A447 A448A440-S444 VanDerWaalsContact O-CB 3.23Å; A440-S444 WeakPolarHBondContact O-CB 3.24Å; A440-S444 PolarHBondContact O-N 3.05Å; G441-S444 WeakPolarHBondContact O-CB 3.47Å; G441-S444 PolarHBondContact O-N 2.84Å; G441-S444 VanDerWaalsContact O-N 3.16Å; L442-S444 VanDerWaalsContact C-N 3.3Å; L442-S444 PolarHBondContact O-N 3.16Å; S444-A447 WeakPolarHBondContact O-CB 3.21Å; S444-A448 VanDerWaalsContact O-CB 3.32Å; S444-A448 WeakPolarHBondContact O-CB 3.37Å; S444-A448 PolarHBondContact O-N 3.17Å
445N53.1Low55.1Low100 Ų10085.1 Ų85.154%0.53548%0.481SS..Hα-helixtrans-73.2-39.1177.4-77.6-24.3000111.4G441 L442 A448 Q449G441-N445 PolarHBondContact O-N 3.4Å; L442-N445 PolarHBondContact O-N 3.26Å; N445-A448 PolarHBondContact O-N 3.3Å; N445-Q449 PolarHBondContact O-N 3.29Å
446F51.4Low56.2Low87 Ų8789.3 Ų89.338%0.38250%0.499SS..Hα-helixtrans-65.1-43171.2-166.3-97.1000111L442 A448 Q449 T450 A457L442-F446 PolarHBondContact O-N 3.41Å; F446-A448 PolarHBondContact O-N 3Å; F446-Q449 PolarHBondContact O-N 2.99Å; F446-T450 HydrophobicContact CE1-CG2 4.35Å; F446-T450 HydrophobicContact CZ-CG2 4.43Å; F446-T450 PolarHBondContact O-N 3.48Å; F446-T450 PolarHBondContact O-OG1 3.2Å; F446-A457 HydrophobicContact CD1-CB 3.94Å
447A46.7Very low56.8Low15 Ų1582.4 Ų82.412%0.12447%0.466CS..Hα-helixtrans-57.3-41.5172.100000113.2A443 S444 T450 G451 M452A443-A447 WeakPolarHBondContact O-CB 3.47Å; A443-A447 PolarHBondContact O-N 2.92Å; S444-A447 WeakPolarHBondContact O-CB 3.21Å; A447-T450 PolarHBondContact O-N 3.42Å; A447-G451 VanDerWaalsContact O-CA 3.23Å; A447-G451 WeakPolarHBondContact O-CA 3.37Å; A447-G451 PolarHBondContact O-N 3.39Å; A447-M452 VanDerWaalsContact CA-O 3.32Å; A447-M452 WeakPolarHBondContact CA-O 3.34Å; A447-M452 WeakPolarHBondContact CB-O 3.32Å; A447-M452 PolarHBondContact O-N 2.87Å
448A56.6Low57.7Low82 Ų8279.2 Ų79.268%0.67845%0.449SS*.Hα-helixtrans-68.7-32.4178.500000112.6S444 N445 F446S444-A448 VanDerWaalsContact O-CB 3.32Å; S444-A448 WeakPolarHBondContact O-CB 3.37Å; S444-A448 PolarHBondContact O-N 3.17Å; N445-A448 PolarHBondContact O-N 3.3Å; F446-A448 PolarHBondContact O-N 3Å
449Q55.4Low59Low174 Ų17479.2 Ų79.281%0.81345%0.445SS*.Hα-helixtrans-78.3-29.5174.6-77.8-176.30.600113.5N445 F446N445-Q449 PolarHBondContact O-N 3.29Å; F446-Q449 PolarHBondContact O-N 2.99Å
450T55Low59.8Low67 Ų6776.2 Ų76.241%0.41143%0.426SS..Hα-helixtrans-112.6-3-174.549.90000115.3F446 A447 M452F446-T450 HydrophobicContact CE1-CG2 4.35Å; F446-T450 HydrophobicContact CZ-CG2 4.43Å; F446-T450 PolarHBondContact O-N 3.48Å; F446-T450 PolarHBondContact O-OG1 3.2Å; A447-T450 PolarHBondContact O-N 3.42Å; T450-M452 VanDerWaalsContact C-N 3.32Å; T450-M452 PolarHBondContact O-N 3.08Å
451G57.8Low60.9Low75 Ų7577.8 Ų77.877%0.77343%0.428SS*.THydrogen-bonded Turntrans67.125.1-178.100000114.6A447A447-G451 VanDerWaalsContact O-CA 3.23Å; A447-G451 WeakPolarHBondContact O-CA 3.37Å; A447-G451 PolarHBondContact O-N 3.39Å
452M52.7Low62.3Low52 Ų5282.5 Ų82.526%0.25644%0.444SS..  trans-110.5149.8-171.2-76.5177.315500113.2A447 T450 R460A447-M452 VanDerWaalsContact CA-O 3.32Å; A447-M452 WeakPolarHBondContact CA-O 3.34Å; A447-M452 WeakPolarHBondContact CB-O 3.32Å; A447-M452 PolarHBondContact O-N 2.87Å; T450-M452 VanDerWaalsContact C-N 3.32Å; T450-M452 PolarHBondContact O-N 3.08Å; M452-R460 VanDerWaalsContact CE-CZ 3.42Å; M452-R460 VanDerWaalsContact SD-CZ 3.53Å; M452-R460 PolarHBondContact SD-NH1 2.91Å
453N68.7Low63.5Low114 Ų11480.8 Ų80.861%0.6143%0.434SS*.  trans-65.2145.1176.7-75.3-16.6000111.2E455 Q456 A457N453-E455 VanDerWaalsContact C-N 3.26Å; N453-E455 PolarHBondContact O-N 2.88Å; N453-Q456 HydrophobicContact CB-CG 4.3Å; N453-Q456 WeakPolarHBondContact O-CB 3.49Å; N453-Q456 PolarHBondContact O-N 3.32Å; N453-A457 PolarHBondContact O-N 3.01Å
454T67.7Low64.7Low51 Ų5184.9 Ų84.931%0.31346%0.455SS..Hα-helixtrans-53.5-41.7179.950.10000112.6A443 Q456 A457 I458A443-T454 HydrophobicContact CB-CG2 3.94Å; T454-Q456 VanDerWaalsContact C-N 3.35Å; T454-Q456 PolarHBondContact O-N 2.86Å; T454-A457 WeakPolarHBondContact O-CB 3.44Å; T454-A457 PolarHBondContact O-N 3.38Å; T454-A457 VanDerWaalsContact O-N 3.16Å; T454-I458 WeakPolarHBondContact O-CG1 3.38Å; T454-I458 PolarHBondContact O-N 3.19Å
455E73.3Confident65.9Low137 Ų13788.9 Ų88.964%0.6447%0.467SS*.Hα-helixtrans-61.4-41.9177.6-159.566.3-163.600112.3N453 A457 I458 E459N453-E455 VanDerWaalsContact C-N 3.26Å; N453-E455 PolarHBondContact O-N 2.88Å; E455-A457 VanDerWaalsContact C-N 3.29Å; E455-A457 PolarHBondContact O-N 3.33Å; E455-I458 PolarHBondContact O-N 3.28Å; E455-E459 WeakPolarHBondContact O-CB 3.26Å; E455-E459 PolarHBondContact O-N 2.93Å
456Q73.8Confident67.1Low98 Ų9890.2 Ų90.246%0.45847%0.47SS..Hα-helixtrans-69.5-30.5177.6-66.1178.6-1300111.8N453 T454 R460N453-Q456 HydrophobicContact CB-CG 4.3Å; N453-Q456 WeakPolarHBondContact O-CB 3.49Å; N453-Q456 PolarHBondContact O-N 3.32Å; T454-Q456 VanDerWaalsContact C-N 3.35Å; T454-Q456 PolarHBondContact O-N 2.86Å; Q456-R460 WeakPolarHBondContact O-CB 3.42Å; Q456-R460 WeakPolarHBondContact O-CG 3.41Å; Q456-R460 PolarHBondContact O-N 2.92Å; Q456-R460 VanDerWaalsContact O-N 3.15Å
457A71.9Confident68.6Low1 Ų188.2 Ų88.21%0.00846%0.462CS..Hα-helixtrans-69.5-44.5174.300000111.1A443 F446 N453 T454 E455 R460 L461A443-A457 HydrophobicContact CB-CB 4.41Å; F446-A457 HydrophobicContact CD1-CB 3.94Å; N453-A457 PolarHBondContact O-N 3.01Å; T454-A457 WeakPolarHBondContact O-CB 3.44Å; T454-A457 PolarHBondContact O-N 3.38Å; T454-A457 VanDerWaalsContact O-N 3.16Å; E455-A457 VanDerWaalsContact C-N 3.29Å; E455-A457 PolarHBondContact O-N 3.33Å; A457-R460 PolarHBondContact O-N 2.91Å; A457-L461 VanDerWaalsContact O-CG 3.32Å; A457-L461 WeakPolarHBondContact O-CG 2.82Å; A457-L461 PolarHBondContact O-N 3.5Å
458I76Confident70.4Confident75 Ų7590 Ų9039%0.38547%0.469SS..Hα-helixtrans-61.8-48.5177.2-66.2165.7000110.6A443 T454 E455 R460 L461 K462A443-I458 HydrophobicContact CB-CD1 4.21Å; A443-I458 HydrophobicContact CB-CG1 3.94Å; T454-I458 WeakPolarHBondContact O-CG1 3.38Å; T454-I458 PolarHBondContact O-N 3.19Å; E455-I458 PolarHBondContact O-N 3.28Å; I458-R460 VanDerWaalsContact C-N 3.27Å; I458-R460 PolarHBondContact O-N 2.92Å; I458-L461 PolarHBondContact O-N 3.17Å; I458-K462 PolarHBondContact O-N 3.22Å
459E75.3Confident71.9Confident107 Ų10786.7 Ų86.750%0.544%0.44SS..Hα-helixtrans-59.1-41.1178.3-175.659.6-157.100111.3E455 K462 M463E455-E459 WeakPolarHBondContact O-CB 3.26Å; E455-E459 PolarHBondContact O-N 2.93Å; E459-K462 PolarHBondContact O-N 3.23Å; E459-M463 VanDerWaalsContact O-CG 3.29Å; E459-M463 WeakPolarHBondContact O-CG 3.31Å; E459-M463 PolarHBondContact O-N 3.28Å
460R71.7Confident73.3Confident115 Ų11579.8 Ų79.843%0.43442%0.416SS..Hα-helixtrans-67.7-39.6176.5-77.5178.4-178.2-171.36.1113.7M452 Q456 A457 I458 K462 M463 L464M452-R460 VanDerWaalsContact CE-CZ 3.42Å; M452-R460 VanDerWaalsContact SD-CZ 3.53Å; M452-R460 PolarHBondContact SD-NH1 2.91Å; Q456-R460 WeakPolarHBondContact O-CB 3.42Å; Q456-R460 WeakPolarHBondContact O-CG 3.41Å; Q456-R460 PolarHBondContact O-N 2.92Å; Q456-R460 VanDerWaalsContact O-N 3.15Å; A457-R460 PolarHBondContact O-N 2.91Å; I458-R460 VanDerWaalsContact C-N 3.27Å; I458-R460 PolarHBondContact O-N 2.92Å; R460-K462 VanDerWaalsContact C-N 3.29Å; R460-M463 PolarHBondContact O-N 3.45Å; R460-L464 WeakPolarHBondContact O-CB 3.25Å; R460-L464 VanDerWaalsContact O-CG 3.29Å; R460-L464 WeakPolarHBondContact O-CG 3.2Å; R460-L464 PolarHBondContact O-N 3.33Å
461L72.9Confident74.6Confident81 Ų8177.5 Ų77.542%0.42441%0.405SS..Hα-helixtrans-61.5-44175.6-74.9168.7000110.1A457 I458 M463 L464 E465A457-L461 VanDerWaalsContact O-CG 3.32Å; A457-L461 WeakPolarHBondContact O-CG 2.82Å; A457-L461 PolarHBondContact O-N 3.5Å; I458-L461 PolarHBondContact O-N 3.17Å; L461-M463 PolarHBondContact O-N 3.03Å; L461-L464 PolarHBondContact O-N 3.25Å; L461-L464 VanDerWaalsContact O-N 3.17Å; L461-E465 WeakPolarHBondContact O-CG 3.46Å; L461-E465 PolarHBondContact O-N 3.45Å
462K76.4Confident75.8Confident112 Ų11280.8 Ų80.849%0.48740%0.401SS..Hα-helixtrans-61.1-45.2175.2-169.1179.7177-173.80112.2I458 E459 R460 L464 E465 E466I458-K462 PolarHBondContact O-N 3.22Å; E459-K462 PolarHBondContact O-N 3.23Å; R460-K462 VanDerWaalsContact C-N 3.29Å; K462-L464 VanDerWaalsContact C-N 3.29Å; K462-L464 PolarHBondContact O-N 2.91Å; K462-E465 PolarHBondContact O-N 2.86Å; K462-E466 WeakPolarHBondContact O-CG 3.27Å; K462-E466 PolarHBondContact O-N 3.35Å
463M76.6Confident77.3Confident93 Ų9382.2 Ų82.246%0.45841%0.407SS..Hα-helixtrans-60.9-36174.5-72-176.277.300113E459 R460 L461 Q467E459-M463 VanDerWaalsContact O-CG 3.29Å; E459-M463 WeakPolarHBondContact O-CG 3.31Å; E459-M463 PolarHBondContact O-N 3.28Å; R460-M463 PolarHBondContact O-N 3.45Å; L461-M463 PolarHBondContact O-N 3.03Å; M463-Q467 VanDerWaalsContact O-CG 3.31Å; M463-Q467 WeakPolarHBondContact O-CG 3.37Å; M463-Q467 PolarHBondContact O-N 2.93Å
464L75.2Confident77.8Confident89 Ų8979.6 Ų79.647%0.46639%0.392SS..Hα-helixtrans-73-39.8176.8-73.6168.8000111.5R460 L461 K462 E466 Q467 I468R460-L464 WeakPolarHBondContact O-CB 3.25Å; R460-L464 VanDerWaalsContact O-CG 3.29Å; R460-L464 WeakPolarHBondContact O-CG 3.2Å; R460-L464 PolarHBondContact O-N 3.33Å; L461-L464 PolarHBondContact O-N 3.25Å; L461-L464 VanDerWaalsContact O-N 3.17Å; K462-L464 VanDerWaalsContact C-N 3.29Å; K462-L464 PolarHBondContact O-N 2.91Å; L464-E466 VanDerWaalsContact C-N 3.32Å; L464-E466 PolarHBondContact O-N 2.96Å; L464-Q467 WeakPolarHBondContact O-CB 3.49Å; L464-Q467 PolarHBondContact O-N 2.88Å; L464-Q467 VanDerWaalsContact O-N 3.13Å; L464-I468 WeakPolarHBondContact O-CG1 3.38Å; L464-I468 PolarHBondContact O-N 3.42Å
465E75.9Confident78.5Confident141 Ų14182.2 Ų82.266%0.65941%0.413SS*.Hα-helixtrans-62-40174.5-76.3-176.616900111.9L461 K462 Q467 I468L461-E465 WeakPolarHBondContact O-CG 3.46Å; L461-E465 PolarHBondContact O-N 3.45Å; K462-E465 PolarHBondContact O-N 2.86Å; E465-Q467 PolarHBondContact O-N 3.17Å; E465-I468 PolarHBondContact O-N 3.41Å
466E78.8Confident79.1Confident128 Ų12879.3 Ų79.360%0.59840%0.402SS*.Hα-helixtrans-63.7-26.4174.1-73.8175.4-171.900113K462 L464 I468K462-E466 WeakPolarHBondContact O-CG 3.27Å; K462-E466 PolarHBondContact O-N 3.35Å; L464-E466 VanDerWaalsContact C-N 3.32Å; L464-E466 PolarHBondContact O-N 2.96Å; E466-I468 VanDerWaalsContact C-N 3.33Å
467Q82.4Confident79.8Confident46 Ų4682.8 Ų82.822%0.21542%0.415CS..Hα-helixtrans-79.5-15.5178.3-74.1173.91200113.9L135 P179 H181 M463 L464 E465L135-Q467 HydrophobicContact CD1-CB 3.82Å; P179-Q467 HydrophobicContact CB-CG 4.29Å; H181-Q467 WeakPolarHBondContact NE2-CA 3.36Å; M463-Q467 VanDerWaalsContact O-CG 3.31Å; M463-Q467 WeakPolarHBondContact O-CG 3.37Å; M463-Q467 PolarHBondContact O-N 2.93Å; L464-Q467 WeakPolarHBondContact O-CB 3.49Å; L464-Q467 PolarHBondContact O-N 2.88Å; L464-Q467 VanDerWaalsContact O-N 3.13Å; E465-Q467 PolarHBondContact O-N 3.17Å
468I84.7Confident80.6Confident53 Ų5386.2 Ų86.227%0.27244%0.444SS..  trans-87.9125.6-176.9-65.1167.4000109.6K133 L464 E465 E466K133-I468 HydrophobicContact CB-CG2 3.49Å; K133-I468 VanDerWaalsContact CB-CG2 3.49Å; K133-I468 HydrophobicContact CD-CG2 3.72Å; K133-I468 HydrophobicContact CG-CG2 3.91Å; L464-I468 WeakPolarHBondContact O-CG1 3.38Å; L464-I468 PolarHBondContact O-N 3.42Å; E465-I468 PolarHBondContact O-N 3.41Å; E466-I468 VanDerWaalsContact C-N 3.33Å
469I88.4Confident81.1Confident12 Ų1284.1 Ų84.16%0.06243%0.433CS..BIsolated β-bridgetrans-119.4147.7-176.753.2167.6000111.6F123 I126 F134 I136 H181F123-I469 HydrophobicContact CD1-CD1 3.85Å; F123-I469 HydrophobicContact CE1-CD1 3.47Å; F123-I469 VanDerWaalsContact CE1-CD1 3.47Å; I126-I469 HydrophobicContact CG2-CB 4.47Å; I126-I469 HydrophobicContact CG2-CD1 4.01Å; I126-I469 HydrophobicContact CG2-CG1 3.99Å; F134-I469 HydrophobicContact CB-CG1 4.36Å; F134-I469 PolarHBondContact N-O 2.82Å; F134-I469 WeakPolarHBondContact O-CG1 3.45Å; F134-I469 PolarHBondContact O-N 3.42Å; I136-I469 HydrophobicContact CD1-CD1 4.08Å; I136-I469 HydrophobicContact CG1-CD1 4.44Å; H181-I469 HydrophobicContact CB-CG2 4.22Å
470G84Confident81.8Confident29 Ų2981.1 Ų81.130%0.29942%0.422SS..  trans164.5137.7174.400000114.4E472G470-E472 PolarHBondContact O-N 2.85Å
471G82.8Confident82.6Confident19 Ų1980.6 Ų80.620%0.19643%0.425CS..  trans76.29.5170.200000117I126 S127 Q473 L474I126-G471 PolarHBondContact O-N 2.78Å; S127-G471 CarbonylContact O-C 3.56Å; G471-Q473 VanDerWaalsContact C-N 3.26Å; G471-Q473 PolarHBondContact O-N 3.5Å; G471-L474 WeakPolarHBondContact O-CD1 3.38Å; G471-L474 VanDerWaalsContact O-CG 3.24Å; G471-L474 WeakPolarHBondContact O-CG 3.38Å; G471-L474 PolarHBondContact O-N 3.45Å
472E83.4Confident83.5Confident144 Ų14482.7 Ų82.767%0.67343%0.43SS*.THydrogen-bonded Turntrans-60.4-30.9-176.3-63.6178-179.200114.3S127 G470S127-E472 PolarHBondContact O-N 2.95Å; G470-E472 PolarHBondContact O-N 2.85Å
473Q82.4Confident84.1Confident82 Ų8278.6 Ų78.638%0.38341%0.412SS..THydrogen-bonded Turntrans-108.818.4-173.7-64.9-178.6-31.300113.2S127 G471 S475 N476 L479S127-Q473 CarbonylContact O-C 3.55Å; S127-Q473 WeakPolarHBondContact O-CA 3.2Å; S127-Q473 PolarHBondContact O-N 2.85Å; S127-Q473 PolarHBondContact OG-OE1 2.89Å; G471-Q473 VanDerWaalsContact C-N 3.26Å; G471-Q473 PolarHBondContact O-N 3.5Å; Q473-S475 PolarHBondContact O-N 3.33Å; Q473-N476 WeakPolarHBondContact O-CB 3.5Å; Q473-N476 PolarHBondContact O-N 3.42Å; Q473-L479 HydrophobicContact CB-CD2 4.01Å; Q473-L479 HydrophobicContact CG-CD2 4.49Å
474L80Confident84.8Confident58 Ų5878.5 Ų78.530%0.30441%0.409SS..THydrogen-bonded Turntrans-60.3-30176.2-70.4171.2000113.3T128 E130 G471 N476T128-L474 VanDerWaalsContact O-CD2 3.29Å; T128-L474 WeakPolarHBondContact O-CD2 3.23Å; E130-L474 HydrophobicContact CB-CD2 4.43Å; E130-L474 HydrophobicContact CG-CD1 3.82Å; E130-L474 HydrophobicContact CG-CD2 3.31Å; E130-L474 HydrophobicContact CG-CG 4.18Å; G471-L474 WeakPolarHBondContact O-CD1 3.38Å; G471-L474 VanDerWaalsContact O-CG 3.24Å; G471-L474 WeakPolarHBondContact O-CG 3.38Å; G471-L474 PolarHBondContact O-N 3.45Å; L474-N476 PolarHBondContact O-N 3.45Å
475S82.3Confident85.5Confident107 Ų10778.4 Ų78.475%0.74841%0.406SS*.THydrogen-bonded Turntrans-66.9-25.1175.260.30000112.9Q473 K477Q473-S475 PolarHBondContact O-N 3.33Å; S475-K477 PolarHBondContact O-N 3.31Å
476N87Confident86.3Confident76 Ų7674.9 Ų74.941%0.40639%0.388SS..  trans-82.779-179-168.1-12.3000111Q473 L474 A478 L479 V480Q473-N476 WeakPolarHBondContact O-CB 3.5Å; Q473-N476 PolarHBondContact O-N 3.42Å; L474-N476 PolarHBondContact O-N 3.45Å; N476-A478 PolarHBondContact O-N 2.91Å; N476-A478 VanDerWaalsContact O-N 3.11Å; N476-L479 HydrophobicContact CB-CB 4.16Å; N476-L479 WeakPolarHBondContact O-CB 3.32Å; N476-L479 PolarHBondContact O-N 3.48Å; N476-L479 PolarHBondContact OD1-N 3.3Å; N476-V480 PolarHBondContact O-N 3.47Å; N476-V480 VanDerWaalsContact O-N 3.14Å
477K86.8Confident86.9Confident170 Ų17072 Ų7274%0.73937%0.374SS*.Hα-helixtrans-52.7-34.8-179.2-64.3-175.6179.5-178.90113.5S475 V480 E481S475-K477 PolarHBondContact O-N 3.31Å; K477-V480 PolarHBondContact O-N 3.45Å; K477-E481 WeakPolarHBondContact O-CB 3.19Å; K477-E481 PolarHBondContact O-N 2.99Å
478A89.7Confident87.4Confident74 Ų7475.8 Ų75.861%0.61239%0.386SS*.Hα-helixtrans-65.6-39.7178.900000112.1N476 K482N476-A478 PolarHBondContact O-N 2.91Å; N476-A478 VanDerWaalsContact O-N 3.11Å; A478-K482 VanDerWaalsContact O-CB 3.25Å; A478-K482 WeakPolarHBondContact O-CB 3.12Å; A478-K482 PolarHBondContact O-N 2.98Å
479L87.2Confident87.7Confident31 Ų3175.1 Ų75.116%0.16238%0.383CS..Hα-helixtrans-68.9-43.7176.4-174.466.6000111.4E124 T128 Q473 N476 E481 K482 R483E124-L479 HydrophobicContact CG-CD1 4.25Å; T128-L479 HydrophobicContact CG2-CD2 3.83Å; T128-L479 HydrophobicContact CG2-CG 3.96Å; Q473-L479 HydrophobicContact CB-CD2 4.01Å; Q473-L479 HydrophobicContact CG-CD2 4.49Å; N476-L479 HydrophobicContact CB-CB 4.16Å; N476-L479 WeakPolarHBondContact O-CB 3.32Å; N476-L479 PolarHBondContact O-N 3.48Å; N476-L479 PolarHBondContact OD1-N 3.3Å; L479-E481 PolarHBondContact O-N 2.88Å; L479-K482 PolarHBondContact O-N 3.3Å; L479-R483 WeakPolarHBondContact O-CB 3.39Å; L479-R483 PolarHBondContact O-N 3.47Å
480V88.1Confident87.8Confident44 Ų4475 Ų7527%0.26738%0.384SS..Hα-helixtrans-59.7-46.5177177.10000110.9T128 N476 K477 R483 K484T128-V480 HydrophobicContact CG2-CG2 4.11Å; N476-V480 PolarHBondContact O-N 3.47Å; N476-V480 VanDerWaalsContact O-N 3.14Å; K477-V480 PolarHBondContact O-N 3.45Å; V480-R483 PolarHBondContact O-N 3.44Å; V480-K484 WeakPolarHBondContact O-CB 3.43Å; V480-K484 PolarHBondContact O-N 3.35Å
481E90.3Very high88.1Confident104 Ų10479 Ų7949%0.48640%0.395SS..Hα-helixtrans-67-41176.5-76-61.1143.800112.3K477 L479 R483 K484 Q485K477-E481 WeakPolarHBondContact O-CB 3.19Å; K477-E481 PolarHBondContact O-N 2.99Å; L479-E481 PolarHBondContact O-N 2.88Å; E481-R483 VanDerWaalsContact C-N 3.31Å; E481-R483 PolarHBondContact O-N 2.71Å; E481-K484 PolarHBondContact O-N 2.89Å; E481-K484 IonicContact OE1-NZ 2.67Å; E481-Q485 WeakPolarHBondContact O-CB 3.45Å; E481-Q485 PolarHBondContact O-N 3.48Å
482K90.3Very high88.6Confident124 Ų12485.5 Ų85.554%0.53941%0.414SS..Hα-helixtrans-58.4-43.2174.1-178.3-178.6179.8-177.50111.5A478 L479 Q485 K486A478-K482 VanDerWaalsContact O-CB 3.25Å; A478-K482 WeakPolarHBondContact O-CB 3.12Å; A478-K482 PolarHBondContact O-N 2.98Å; L479-K482 PolarHBondContact O-N 3.3Å; K482-Q485 WeakPolarHBondContact O-CB 3.48Å; K482-Q485 PolarHBondContact O-N 3.15Å; K482-K486 WeakPolarHBondContact O-CG 3.25Å; K482-K486 PolarHBondContact O-N 3.49Å
483R89.8Confident88.8Confident26 Ų2682.5 Ų82.510%0.09840%0.396CS..Hα-helixtrans-65-45.8176.2177.7-179.41756714.7111.7E78 T128 L479 V480 E481 Q485 K486 K487E78-R483 IonicContact OE1-CZ 2.89Å; E78-R483 IonicContact OE1-NH1 3.79Å; E78-R483 IonicContact OE1-NH2 3.99Å; E78-R483 PolarHBondContact OE1-NH2 3.43Å; E78-R483 IonicContact OE2-NH2 3.64Å; T128-R483 WeakPolarHBondContact OG1-CD 3.43Å; T128-R483 PolarHBondContact OG1-NE 2.98Å; L479-R483 WeakPolarHBondContact O-CB 3.39Å; L479-R483 PolarHBondContact O-N 3.47Å; V480-R483 PolarHBondContact O-N 3.44Å; E481-R483 VanDerWaalsContact C-N 3.31Å; E481-R483 PolarHBondContact O-N 2.71Å; R483-Q485 PolarHBondContact O-N 2.88Å; R483-K486 PolarHBondContact O-N 3.36Å; R483-K486 VanDerWaalsContact O-N 3.16Å; R483-K487 PolarHBondContact O-N 3.21Å
484K90.5Very high88.9Confident91 Ų9181.7 Ų81.740%0.39639%0.39SS..Hα-helixtrans-58.2-38.7176.5-168.7179.5-173.81790111.3V480 E481 R488V480-K484 WeakPolarHBondContact O-CB 3.43Å; V480-K484 PolarHBondContact O-N 3.35Å; E481-K484 PolarHBondContact O-N 2.89Å; E481-K484 IonicContact OE1-NZ 2.67Å; K484-R488 VanDerWaalsContact O-CG 3.29Å; K484-R488 WeakPolarHBondContact O-CG 3.08Å; K484-R488 PolarHBondContact O-N 2.88Å
485Q91.5Very high89.3Confident88 Ų8887 Ų8741%0.41141%0.405SS..Hα-helixtrans-64.8-50.5173.2-176.257.231.300111.9E481 K482 R483 K487 R488 D489E481-Q485 WeakPolarHBondContact O-CB 3.45Å; E481-Q485 PolarHBondContact O-N 3.48Å; K482-Q485 WeakPolarHBondContact O-CB 3.48Å; K482-Q485 PolarHBondContact O-N 3.15Å; R483-Q485 PolarHBondContact O-N 2.88Å; Q485-K487 VanDerWaalsContact C-N 3.29Å; Q485-K487 PolarHBondContact O-N 2.88Å; Q485-R488 PolarHBondContact O-N 3.07Å; Q485-D489 PolarHBondContact NE2-OD1 3.08Å; Q485-D489 PolarHBondContact NE2-OD2 3.33Å; Q485-D489 VanDerWaalsContact O-CG 3.27Å; Q485-D489 PolarHBondContact O-N 3.29Å
486K91.8Very high89.5Confident67 Ų6787 Ų8729%0.29139%0.393SS..Hα-helixtrans-55.4-42.9175.7-73.2175.7176.1173.60112.4Y74 E124 K482 R483 D489 A490Y74-K486 HydrophobicContact CE2-CB 4.16Å; Y74-K486 HydrophobicContact CE2-CD 4.43Å; Y74-K486 WeakPolarHBondContact OH-CB 3.36Å; E124-K486 VanDerWaalsContact CD-NZ 3.29Å; E124-K486 IonicContact OE1-NZ 3.03Å; E124-K486 PolarHBondContact OE1-NZ 3.45Å; E124-K486 IonicContact OE2-NZ 3.45Å; E124-K486 PolarHBondContact OE2-NZ 3.15Å; K482-K486 WeakPolarHBondContact O-CG 3.25Å; K482-K486 PolarHBondContact O-N 3.49Å; R483-K486 PolarHBondContact O-N 3.36Å; R483-K486 VanDerWaalsContact O-N 3.16Å; K486-D489 PolarHBondContact O-N 2.92Å; K486-A490 WeakPolarHBondContact O-CB 3.45Å; K486-A490 PolarHBondContact O-N 3.17Å
487K90.9Very high89.4Confident66 Ų6686.2 Ų86.229%0.28739%0.388SS..Hα-helixtrans-62.5-47.2177.2-175.1167.6-176.2141.50111.8E78 R483 Q485 D489 A490 E491E78-K487 WeakPolarHBondContact OE2-CD 3.41Å; E78-K487 WeakPolarHBondContact OE2-CE 3.49Å; E78-K487 IonicContact OE2-NZ 3.8Å; E78-K487 PolarHBondContact OE2-NZ 2.84Å; R483-K487 PolarHBondContact O-N 3.21Å; Q485-K487 VanDerWaalsContact C-N 3.29Å; Q485-K487 PolarHBondContact O-N 2.88Å; K487-D489 VanDerWaalsContact C-N 3.33Å; K487-D489 PolarHBondContact O-N 3.41Å; K487-A490 PolarHBondContact O-N 3.05Å; K487-E491 WeakPolarHBondContact O-CG 3.25Å; K487-E491 PolarHBondContact O-N 2.82Å
488R92.9Very high89.3Confident126 Ų12684 Ų8448%0.47538%0.375SS..Hα-helixtrans-61.2-40.1175.1-74170.4175.1176.6-4.4112.4K484 Q485 E491 R492K484-R488 VanDerWaalsContact O-CG 3.29Å; K484-R488 WeakPolarHBondContact O-CG 3.08Å; K484-R488 PolarHBondContact O-N 2.88Å; Q485-R488 PolarHBondContact O-N 3.07Å; R488-E491 PolarHBondContact O-N 3.03Å; R488-R492 WeakPolarHBondContact O-CB 2.86Å; R488-R492 PolarHBondContact O-N 3.35Å
489D92.4Very high89.1Confident39 Ų3984.8 Ų84.821%0.20937%0.366CS..Hα-helixtrans-68-40.3178.3-68.1-27.3000111.3Q485 K486 K487 R492 R493Q485-D489 PolarHBondContact NE2-OD1 3.08Å; Q485-D489 PolarHBondContact NE2-OD2 3.33Å; Q485-D489 VanDerWaalsContact O-CG 3.27Å; Q485-D489 PolarHBondContact O-N 3.29Å; K486-D489 PolarHBondContact O-N 2.92Å; K487-D489 VanDerWaalsContact C-N 3.33Å; K487-D489 PolarHBondContact O-N 3.41Å; D489-R492 WeakPolarHBondContact O-CB 3.17Å; D489-R492 PolarHBondContact O-N 2.94Å; D489-R493 VanDerWaalsContact O-CG 3.31Å; D489-R493 WeakPolarHBondContact O-CG 3.12Å; D489-R493 PolarHBondContact O-N 3.36Å
490A89.8Confident88.8Confident10 Ų1087 Ų878%0.08338%0.377CS..Hα-helixtrans-64.2-40.9173.400000112.4Y74 K486 K487 R493 R494Y74-A490 HydrophobicContact CD1-CB 3.32Å; Y74-A490 HydrophobicContact CE1-CB 3.7Å; Y74-A490 HydrophobicContact CG-CB 4.12Å; K486-A490 WeakPolarHBondContact O-CB 3.45Å; K486-A490 PolarHBondContact O-N 3.17Å; K487-A490 PolarHBondContact O-N 3.05Å; A490-R493 PolarHBondContact O-N 2.93Å; A490-R494 WeakPolarHBondContact O-CB 3.08Å; A490-R494 PolarHBondContact O-N 3.03Å
491E90.7Very high88.5Confident113 Ų11388.2 Ų88.253%0.52838%0.38SS..Hα-helixtrans-63.4-40.9173.7-75.1173.7-172.500112.1K487 R488 R494 R495K487-E491 WeakPolarHBondContact O-CG 3.25Å; K487-E491 PolarHBondContact O-N 2.82Å; R488-E491 PolarHBondContact O-N 3.03Å; E491-R494 PolarHBondContact O-N 3.39Å; E491-R495 WeakPolarHBondContact O-CB 3.4Å; E491-R495 PolarHBondContact O-N 2.83Å
492R92Very high88.1Confident156 Ų15691 Ų9159%0.58939%0.386SS*.Hα-helixtrans-60.4-49.2174.4-175.5-173.7-62.2-169.11111.1R488 D489 R494 R495 Q496R488-R492 WeakPolarHBondContact O-CB 2.86Å; R488-R492 PolarHBondContact O-N 3.35Å; D489-R492 WeakPolarHBondContact O-CB 3.17Å; D489-R492 PolarHBondContact O-N 2.94Å; R492-R494 PolarHBondContact O-N 2.76Å; R492-R495 WeakPolarHBondContact O-CB 3.5Å; R492-R495 PolarHBondContact O-N 3.42Å; R492-Q496 WeakPolarHBondContact O-CG 3.36Å; R492-Q496 PolarHBondContact O-N 2.92Å
493R87.8Confident87.7Confident81 Ų8188 Ų8831%0.30638%0.38SS..Hα-helixtrans-59-47.5176.5-71176.2-175.5102.44.7111.3D71 D489 A490 R495 Q496 M497D71-R493 WeakPolarHBondContact OD1-CD 3.3Å; D71-R493 IonicContact OD1-NE 3.47Å; D71-R493 PolarHBondContact OD1-NE 3Å; D489-R493 VanDerWaalsContact O-CG 3.31Å; D489-R493 WeakPolarHBondContact O-CG 3.12Å; D489-R493 PolarHBondContact O-N 3.36Å; A490-R493 PolarHBondContact O-N 2.93Å; R493-R495 VanDerWaalsContact C-N 3.25Å; R493-R495 PolarHBondContact O-N 2.82Å; R493-Q496 WeakPolarHBondContact O-CB 3.16Å; R493-Q496 PolarHBondContact O-N 2.96Å; R493-Q496 VanDerWaalsContact O-N 3.12Å; R493-M497 WeakPolarHBondContact O-CG 3.15Å; R493-M497 PolarHBondContact O-N 3.2Å
494R85.6Confident87Confident65 Ų6589.6 Ų89.625%0.24539%0.386CS..Hα-helixtrans-58.8-37.8177.5-171.5178.9-174-170.23.3112.2A490 E491 R492 R498A490-R494 WeakPolarHBondContact O-CB 3.08Å; A490-R494 PolarHBondContact O-N 3.03Å; E491-R494 PolarHBondContact O-N 3.39Å; R492-R494 PolarHBondContact O-N 2.76Å; R494-R498 VanDerWaalsContact NH2-NH2 3.19Å; R494-R498 WeakPolarHBondContact O-CG 2.73Å; R494-R498 PolarHBondContact O-N 3.13Å
495R87.8Confident86.3Confident168 Ų16889.2 Ų89.263%0.63439%0.386SS*.Hα-helixtrans-67.9-45.6175.4-177175.2177.9158.51.1111.6E491 R492 R493 M497 R498 E499E491-R495 WeakPolarHBondContact O-CB 3.4Å; E491-R495 PolarHBondContact O-N 2.83Å; R492-R495 WeakPolarHBondContact O-CB 3.5Å; R492-R495 PolarHBondContact O-N 3.42Å; R493-R495 VanDerWaalsContact C-N 3.25Å; R493-R495 PolarHBondContact O-N 2.82Å; R495-M497 PolarHBondContact O-N 2.97Å; R495-R498 PolarHBondContact O-N 3.22Å; R495-E499 HydrophobicContact CG-CG 4.36Å; R495-E499 WeakPolarHBondContact CG-OE1 3.33Å; R495-E499 IonicContact CZ-OE1 3.51Å; R495-E499 IonicContact NE-OE1 3.71Å; R495-E499 PolarHBondContact NE-OE1 3.27Å; R495-E499 IonicContact NH2-OE1 2.73Å; R495-E499 WeakPolarHBondContact O-CB 3.42Å; R495-E499 WeakPolarHBondContact O-CG 3.07Å; R495-E499 PolarHBondContact O-N 3.44Å
496Q87.3Confident85.6Confident107 Ų10788.9 Ų88.950%0.539%0.386SS..Hα-helixtrans-58.6-45.1176.5-72.9171.9-26.600112R492 R493 R498 E499 M500R492-Q496 WeakPolarHBondContact O-CG 3.36Å; R492-Q496 PolarHBondContact O-N 2.92Å; R493-Q496 WeakPolarHBondContact O-CB 3.16Å; R493-Q496 PolarHBondContact O-N 2.96Å; R493-Q496 VanDerWaalsContact O-N 3.12Å; Q496-R498 VanDerWaalsContact C-N 3.34Å; Q496-R498 PolarHBondContact O-N 2.97Å; Q496-E499 PolarHBondContact O-N 2.78Å; Q496-M500 WeakPolarHBondContact O-CB 3.45Å; Q496-M500 PolarHBondContact O-N 3.23Å
497M84Confident84.7Confident60 Ų6091.6 Ų91.630%0.29640%0.4SS..Hα-helixtrans-61.9-41.1177.2-62.8-55.2-70.900112.1D56 A57 R493 R495 M500 E501D56-M497 WeakPolarHBondContact O-CE 3.46Å; A57-M497 HydrophobicContact CB-CE 4Å; R493-M497 WeakPolarHBondContact O-CG 3.15Å; R493-M497 PolarHBondContact O-N 3.2Å; R495-M497 PolarHBondContact O-N 2.97Å; M497-M500 PolarHBondContact O-N 2.68Å; M497-E501 WeakPolarHBondContact O-CB 3.39Å; M497-E501 PolarHBondContact O-N 3.34Å
498R84.4Confident83.5Confident125 Ų12593.1 Ų93.147%0.47241%0.408SS..Hα-helixtrans-67.4-38.4175.3-75.3174.2170-177-5.2112.8R494 R495 Q496 R502R494-R498 VanDerWaalsContact NH2-NH2 3.19Å; R494-R498 WeakPolarHBondContact O-CG 2.73Å; R494-R498 PolarHBondContact O-N 3.13Å; R495-R498 PolarHBondContact O-N 3.22Å; Q496-R498 VanDerWaalsContact C-N 3.34Å; Q496-R498 PolarHBondContact O-N 2.97Å; R498-R502 WeakPolarHBondContact O-CB 3.15Å; R498-R502 VanDerWaalsContact O-CG 3.24Å; R498-R502 WeakPolarHBondContact O-CG 3.33Å; R498-R502 PolarHBondContact O-N 3.27Å
499E85.6Confident82.3Confident90 Ų9092.7 Ų92.742%0.42141%0.411SS..Hα-helixtrans-68.2-39.6176.4-76.2173.4-177.700110.9R495 Q496 R502 S503R495-E499 HydrophobicContact CG-CG 4.36Å; R495-E499 WeakPolarHBondContact CG-OE1 3.33Å; R495-E499 IonicContact CZ-OE1 3.51Å; R495-E499 IonicContact NE-OE1 3.71Å; R495-E499 PolarHBondContact NE-OE1 3.27Å; R495-E499 IonicContact NH2-OE1 2.73Å; R495-E499 WeakPolarHBondContact O-CB 3.42Å; R495-E499 WeakPolarHBondContact O-CG 3.07Å; R495-E499 PolarHBondContact O-N 3.44Å; Q496-E499 PolarHBondContact O-N 2.78Å; E499-R502 PolarHBondContact O-N 2.92Å; E499-S503 VanDerWaalsContact O-CB 3.23Å; E499-S503 WeakPolarHBondContact O-CB 3.44Å; E499-S503 PolarHBondContact O-N 3.13Å
500M81.4Confident81Confident77 Ų7796.4 Ų96.438%0.37943%0.428SS..Hα-helixtrans-62.2-46.9172.8-175.7-173.8-69.800111.2S34 C36 Q496 M497 R502 S503 R504S34-M500 WeakPolarHBondContact O-CE 3.48Å; C36-M500 VanDerWaalsContact SG-SD 3.65Å; Q496-M500 WeakPolarHBondContact O-CB 3.45Å; Q496-M500 PolarHBondContact O-N 3.23Å; M497-M500 PolarHBondContact O-N 2.68Å; M500-R502 PolarHBondContact O-N 2.78Å; M500-S503 PolarHBondContact O-N 2.93Å; M500-R504 WeakPolarHBondContact O-CB 3.47Å; M500-R504 PolarHBondContact O-N 3.45Å
501E81.4Confident79.6Confident70 Ų70100 Ų10033%0.32744%0.444SS..Hα-helixtrans-60.6-45.5176.2-172.2-175.7-170.500111.7M497 R504 Q505M497-E501 WeakPolarHBondContact O-CB 3.39Å; M497-E501 PolarHBondContact O-N 3.34Å; E501-R504 WeakPolarHBondContact O-CB 3.27Å; E501-R504 PolarHBondContact O-N 3.31Å; E501-Q505 WeakPolarHBondContact O-CG 3.34Å; E501-Q505 PolarHBondContact O-N 3.42Å
502R82.2Confident78.1Confident162 Ų162100.3 Ų100.361%0.61145%0.447SS*.Hα-helixtrans-66-43.8176.7-76.7176.8-177.3-169.6-0.7112.5R498 E499 M500 R504 Q505 L506R498-R502 WeakPolarHBondContact O-CB 3.15Å; R498-R502 VanDerWaalsContact O-CG 3.24Å; R498-R502 WeakPolarHBondContact O-CG 3.33Å; R498-R502 PolarHBondContact O-N 3.27Å; E499-R502 PolarHBondContact O-N 2.92Å; M500-R502 PolarHBondContact O-N 2.78Å; R502-R504 PolarHBondContact O-N 3.01Å; R502-Q505 PolarHBondContact O-N 3.46Å; R502-L506 WeakPolarHBondContact O-CB 3.29Å; R502-L506 VanDerWaalsContact O-CD1 3.26Å; R502-L506 WeakPolarHBondContact O-CD1 3.45Å; R502-L506 PolarHBondContact O-N 2.87Å
503S81.3Confident76.4Confident60 Ų6097.3 Ų97.342%0.4244%0.442SS..Hα-helixtrans-61-36.2177.2-175.90000110.6E499 M500 Q507E499-S503 VanDerWaalsContact O-CB 3.23Å; E499-S503 WeakPolarHBondContact O-CB 3.44Å; E499-S503 PolarHBondContact O-N 3.13Å; M500-S503 PolarHBondContact O-N 2.93Å; S503-Q507 WeakPolarHBondContact O-CB 3.41Å; S503-Q507 VanDerWaalsContact O-CG 3.25Å; S503-Q507 WeakPolarHBondContact O-CG 3.49Å; S503-Q507 PolarHBondContact O-N 2.64Å
504R76.7Confident74.9Confident61 Ų6196.9 Ų96.923%0.2346%0.456CS..Hα-helixtrans-68.3-47174.2-173.417867.289.90.1111.9M500 E501 R502 L506 Q507 E508M500-R504 WeakPolarHBondContact O-CB 3.47Å; M500-R504 PolarHBondContact O-N 3.45Å; E501-R504 WeakPolarHBondContact O-CB 3.27Å; E501-R504 PolarHBondContact O-N 3.31Å; R502-R504 PolarHBondContact O-N 3.01Å; R504-L506 VanDerWaalsContact C-N 3.29Å; R504-L506 PolarHBondContact O-N 3.39Å; R504-Q507 PolarHBondContact O-N 2.97Å; R504-Q507 VanDerWaalsContact O-N 3.13Å; R504-E508 IonicContact NH1-OE1 3.34Å; R504-E508 PolarHBondContact NH1-OE1 2.9Å; R504-E508 PolarHBondContact O-N 3.41Å
505Q75.2Confident73.4Confident82 Ų8296.2 Ų96.238%0.38345%0.454SS..Hα-helixtrans-59.1-42.4174.3-72.9172.4200111.2E501 R502 E508 E509E501-Q505 WeakPolarHBondContact O-CG 3.34Å; E501-Q505 PolarHBondContact O-N 3.42Å; R502-Q505 PolarHBondContact O-N 3.46Å; Q505-E508 WeakPolarHBondContact O-CB 3.12Å; Q505-E508 PolarHBondContact O-N 3.3Å; Q505-E509 WeakPolarHBondContact O-CB 3.19Å; Q505-E509 WeakPolarHBondContact O-CG 3.4Å; Q505-E509 PolarHBondContact O-N 3.06Å
506L77.1Confident71.9Confident81 Ų8196 Ų9642%0.42446%0.458SS..Hα-helixtrans-66.3-36.2173.9-97.596.5000112.4R502 R504 E508 E509 Q510R502-L506 WeakPolarHBondContact O-CB 3.29Å; R502-L506 VanDerWaalsContact O-CD1 3.26Å; R502-L506 WeakPolarHBondContact O-CD1 3.45Å; R502-L506 PolarHBondContact O-N 2.87Å; R504-L506 VanDerWaalsContact C-N 3.29Å; R504-L506 PolarHBondContact O-N 3.39Å; L506-E508 VanDerWaalsContact C-N 3.32Å; L506-E509 PolarHBondContact O-N 2.94Å; L506-Q510 WeakPolarHBondContact O-CA 3.45Å; L506-Q510 WeakPolarHBondContact O-CB 3.45Å; L506-Q510 WeakPolarHBondContact O-CG 3.45Å; L506-Q510 PolarHBondContact O-N 3.03Å
507Q71.3Confident70.6Confident124 Ų12496.8 Ų96.858%0.57947%0.465SS*.Hα-helixtrans-64.7-40.5173.5-79.11715.200110.8S503 R504 M511S503-Q507 WeakPolarHBondContact O-CB 3.41Å; S503-Q507 VanDerWaalsContact O-CG 3.25Å; S503-Q507 WeakPolarHBondContact O-CG 3.49Å; S503-Q507 PolarHBondContact O-N 2.64Å; R504-Q507 PolarHBondContact O-N 2.97Å; R504-Q507 VanDerWaalsContact O-N 3.13Å; Q507-M511 WeakPolarHBondContact O-CB 3.45Å; Q507-M511 PolarHBondContact O-N 3.24Å
508E67.6Low69.3Low99 Ų9998.6 Ų98.646%0.46348%0.479SS..Hα-helixtrans-62.9-41.3172.7-71.2174.1-161.900111.5R504 Q505 L506 M512R504-E508 IonicContact NH1-OE1 3.34Å; R504-E508 PolarHBondContact NH1-OE1 2.9Å; R504-E508 PolarHBondContact O-N 3.41Å; Q505-E508 WeakPolarHBondContact O-CB 3.12Å; Q505-E508 PolarHBondContact O-N 3.3Å; L506-E508 VanDerWaalsContact C-N 3.32Å; E508-M512 VanDerWaalsContact O-CG 3.25Å; E508-M512 WeakPolarHBondContact O-CG 3.45Å; E508-M512 PolarHBondContact O-N 2.7Å
509E67.6Low67.8Low116 Ų116100.3 Ų100.354%0.54250%0.498SS..Hα-helixtrans-76.4-39.5178.4-74.4178.6176.100114.1Q505 L506 M512 D513Q505-E509 WeakPolarHBondContact O-CB 3.19Å; Q505-E509 WeakPolarHBondContact O-CG 3.4Å; Q505-E509 PolarHBondContact O-N 3.06Å; L506-E509 PolarHBondContact O-N 2.94Å; E509-M512 CarbonylContact O-C 3.4Å; E509-M512 VanDerWaalsContact O-C 3.3Å; E509-M512 WeakPolarHBondContact O-CA 3.28Å; E509-M512 WeakPolarHBondContact O-CB 3.45Å; E509-M512 PolarHBondContact O-N 2.99Å; E509-D513 PolarHBondContact O-N 3.48Å
510Q64.8Low66.4Low117 Ų117101.3 Ų101.355%0.54750%0.502SS..Hα-helixtrans-70.8-36.2177.4-76.3178.51.200111L506 M512 D513 A514L506-Q510 WeakPolarHBondContact O-CA 3.45Å; L506-Q510 WeakPolarHBondContact O-CB 3.45Å; L506-Q510 WeakPolarHBondContact O-CG 3.45Å; L506-Q510 PolarHBondContact O-N 3.03Å; Q510-M512 PolarHBondContact O-N 3.49Å; Q510-D513 PolarHBondContact O-N 3.43Å; Q510-A514 WeakPolarHBondContact O-CB 3.41Å; Q510-A514 PolarHBondContact O-N 3.16Å
511M60.4Low65.6Low85 Ų85100 Ų10042%0.41950%0.499SS..Hα-helixtrans-52.3-48.6163.3-177.2169.370.900108.1Q507 D513 Y515 M531Q507-M511 WeakPolarHBondContact O-CB 3.45Å; Q507-M511 PolarHBondContact O-N 3.24Å; M511-D513 PolarHBondContact O-N 3.35Å; M511-Y515 HydrophobicContact CG-CE2 4.08Å; M511-Y515 WeakPolarHBondContact CG-OH 3.18Å; M511-Y515 WeakPolarHBondContact O-CD1 3.15Å; M511-Y515 WeakPolarHBondContact O-CD2 3.46Å; M511-Y515 WeakPolarHBondContact O-CE1 3.31Å; M511-Y515 WeakPolarHBondContact O-CE2 3.35Å; M511-Y515 VanDerWaalsContact O-CG 3.22Å; M511-M531 HydrophobicContact CE-SD 4.12Å; M511-M531 HydrophobicContact SD-CE 3.9Å; M511-M531 HydrophobicContact SD-SD 4.03Å
512M59.3Low64.8Low120 Ų120102.8 Ų102.859%0.59152%0.515SS*.Hα-helixtrans-62.1-32.4176-67.6-73.3-102.400116.3E508 E509 Q510 Y515E508-M512 VanDerWaalsContact O-CG 3.25Å; E508-M512 WeakPolarHBondContact O-CG 3.45Å; E508-M512 PolarHBondContact O-N 2.7Å; E509-M512 CarbonylContact O-C 3.4Å; E509-M512 VanDerWaalsContact O-C 3.3Å; E509-M512 WeakPolarHBondContact O-CA 3.28Å; E509-M512 WeakPolarHBondContact O-CB 3.45Å; E509-M512 PolarHBondContact O-N 2.99Å; Q510-M512 PolarHBondContact O-N 3.49Å; M512-Y515 VanDerWaalsContact CA-CE2 3.43Å; M512-Y515 HydrophobicContact CB-CD2 4.39Å; M512-Y515 HydrophobicContact CG-CE2 4.47Å; M512-Y515 WeakPolarHBondContact O-CB 3.47Å; M512-Y515 WeakPolarHBondContact O-CD2 3.47Å; M512-Y515 HydrophobicContact SD-CD2 4.26Å; M512-Y515 HydrophobicContact SD-CE2 3.97Å
513D55.4Low64.1Low93 Ų93102.3 Ų102.350%0.49752%0.52SS..Hα-helixtrans-95.2-28-174.3-90.4-32.4000114.8E509 Q510 M511 Y515 K516E509-D513 PolarHBondContact O-N 3.48Å; Q510-D513 PolarHBondContact O-N 3.43Å; M511-D513 PolarHBondContact O-N 3.35Å; D513-Y515 PolarHBondContact O-N 3.35Å; D513-K516 PolarHBondContact O-N 2.92Å; D513-K516 IonicContact OD1-NZ 3.79Å; D513-K516 PolarHBondContact OD1-NZ 3.08Å
514A56.4Low63.4Low72 Ų72101.1 Ų101.160%0.59551%0.509SS*.THydrogen-bonded Turntrans-60.1-2.6168.500000112.9Q510Q510-A514 WeakPolarHBondContact O-CB 3.41Å; Q510-A514 PolarHBondContact O-N 3.16Å
515Y53.7Low63.3Low52 Ų52102.1 Ų102.120%0.20452%0.521CS..THydrogen-bonded Turntrans-90.97.6-177.4-62.4-43000116.6M511 M512 D513 K528M511-Y515 HydrophobicContact CG-CE2 4.08Å; M511-Y515 WeakPolarHBondContact CG-OH 3.18Å; M511-Y515 WeakPolarHBondContact O-CD1 3.15Å; M511-Y515 WeakPolarHBondContact O-CD2 3.46Å; M511-Y515 WeakPolarHBondContact O-CE1 3.31Å; M511-Y515 WeakPolarHBondContact O-CE2 3.35Å; M511-Y515 VanDerWaalsContact O-CG 3.22Å; M512-Y515 VanDerWaalsContact CA-CE2 3.43Å; M512-Y515 HydrophobicContact CB-CD2 4.39Å; M512-Y515 HydrophobicContact CG-CE2 4.47Å; M512-Y515 WeakPolarHBondContact O-CB 3.47Å; M512-Y515 WeakPolarHBondContact O-CD2 3.47Å; M512-Y515 HydrophobicContact SD-CD2 4.26Å; M512-Y515 HydrophobicContact SD-CE2 3.97Å; D513-Y515 PolarHBondContact O-N 3.35Å; Y515-K528 VanDerWaalsContact CB-CE 3.48Å; Y515-K528 HydrophobicContact CD1-CD 4.35Å; Y515-K528 HydrophobicContact CD1-CG 4.42Å; Y515-K528 HydrophobicContact CD2-CD 4.43Å; Y515-K528 HydrophobicContact CE1-CD 4.37Å; Y515-K528 VanDerWaalsContact CE1-CE 3.41Å; Y515-K528 HydrophobicContact CE1-CG 4.01Å; Y515-K528 HydrophobicContact CE2-CD 4.47Å; Y515-K528 HydrophobicContact CG-CD 4.42Å
516K56.4Low63.4Low163 Ų163104.1 Ų104.171%0.70953%0.531SS*.  trans-99-3.2-176.1-70.2176.1-176.5145.50116.4D513D513-K516 PolarHBondContact O-N 2.92Å; D513-K516 IonicContact OD1-NZ 3.79Å; D513-K516 PolarHBondContact OD1-NZ 3.08Å
517D60.7Low63.4Low123 Ų123102.1 Ų102.166%0.65853%0.53SS*.  trans-96.9134.6-176.2-158.89.7000114.5T521D517-T521 VanDerWaalsContact O-CG2 3.24Å; D517-T521 WeakPolarHBondContact O-CG2 3.27Å
518V55.7Low63.2Low98 Ų9899.4 Ų99.459%0.59452%0.516SS*.SBendtrans-78.6-32.8-144.9174.70000116.4T521V518-T521 WeakPolarHBondContact O-CB 2.87Å; V518-T521 WeakPolarHBondContact O-CG2 3.38Å; V518-T521 PolarHBondContact O-OG1 3.31Å
519N53.5Low63.8Low161 Ų16199.1 Ų99.186%0.86152%0.517SS*.SBendtrans-96.2-18.7-178-91.8-3.9000114T521N519-T521 PolarHBondContact O-N 3.27Å
520H56.7Low64.6Low111 Ų11197.9 Ų97.951%0.51451%0.511SS..SBendtrans-73.3-12.5167.1-164.1-150.4000110.7L522 N524H520-L522 PolarHBondContact O-N 2.95Å; H520-N524 PolarHBondContact CD2-OD1 3.36Å; H520-N524 PolarHBondContact CE1-ND2 2.91Å; H520-N524 PolarHBondContact CE1-OD1 2.8Å; H520-N524 PolarHBondContact ND1-ND2 2.76Å; H520-N524 PolarHBondContact NE2-OD1 2.85Å; H520-N524 VanDerWaalsContact NE2-OD1 3.1Å; H520-N524 WeakPolarHBondContact O-CB 3.41Å; H520-N524 PolarHBondContact O-N 2.96Å; H520-N524 PolarHBondContact O-ND2 3.33Å
521T63.6Low65.3Low50 Ų5096.1 Ų96.131%0.30750%0.504SS..Hα-helixtrans-59.8-40.4-173.259.20000115.3D517 V518 N519 N524 V525D517-T521 VanDerWaalsContact O-CG2 3.24Å; D517-T521 WeakPolarHBondContact O-CG2 3.27Å; V518-T521 WeakPolarHBondContact O-CB 2.87Å; V518-T521 WeakPolarHBondContact O-CG2 3.38Å; V518-T521 PolarHBondContact O-OG1 3.31Å; N519-T521 PolarHBondContact O-N 3.27Å; T521-N524 PolarHBondContact O-N 3.08Å; T521-V525 WeakPolarHBondContact O-CA 3.02Å; T521-V525 WeakPolarHBondContact O-CB 3.29Å; T521-V525 WeakPolarHBondContact O-CG2 3.32Å; T521-V525 PolarHBondContact O-N 3.28Å
522L66.4Low66.4Low129 Ų12996 Ų9668%0.67550%0.503SS*.Hα-helixtrans-69.1-49.3-173.8-92.5167000112.1H520 N524 V525 Q526H520-L522 PolarHBondContact O-N 2.95Å; L522-N524 VanDerWaalsContact C-N 3.31Å; L522-N524 PolarHBondContact O-N 3.16Å; L522-V525 PolarHBondContact O-N 3Å; L522-Q526 WeakPolarHBondContact O-CB 3.34Å; L522-Q526 VanDerWaalsContact O-CG 3.31Å; L522-Q526 WeakPolarHBondContact O-CG 3.47Å; L522-Q526 PolarHBondContact O-N 3.24Å
523Q66.1Low67.6Low152 Ų15295.1 Ų95.171%0.7150%0.495SS*.Hα-helixtrans-64.8-38.1175.4-70.2-179.7-600111.1Q526 G527Q523-Q526 PolarHBondContact O-N 3.21Å; Q523-G527 PolarHBondContact O-N 3.47Å
524N67Low68.9Low34 Ų3498.9 Ų98.918%0.18250%0.503CS..Hα-helixtrans-69.9-39.7176-72.9-9.9000114.1H520 T521 L522 Q526 G527 K528H520-N524 PolarHBondContact CD2-OD1 3.36Å; H520-N524 PolarHBondContact CE1-ND2 2.91Å; H520-N524 PolarHBondContact CE1-OD1 2.8Å; H520-N524 PolarHBondContact ND1-ND2 2.76Å; H520-N524 PolarHBondContact NE2-OD1 2.85Å; H520-N524 VanDerWaalsContact NE2-OD1 3.1Å; H520-N524 WeakPolarHBondContact O-CB 3.41Å; H520-N524 PolarHBondContact O-N 2.96Å; H520-N524 PolarHBondContact O-ND2 3.33Å; T521-N524 PolarHBondContact O-N 3.08Å; L522-N524 VanDerWaalsContact C-N 3.31Å; L522-N524 PolarHBondContact O-N 3.16Å; N524-Q526 VanDerWaalsContact C-N 3.31Å; N524-G527 CarbonylContact O-C 3.52Å; N524-G527 PolarHBondContact O-N 3.44Å; N524-K528 WeakPolarHBondContact O-CB 3.48Å; N524-K528 WeakPolarHBondContact O-CG 3.28Å; N524-K528 PolarHBondContact O-N 3.48Å
525V74.3Confident70.1Confident82 Ų82102.9 Ų102.950%0.49750%0.502SS..Hα-helixtrans-68.6-36.9177.5168.40000108.9T521 L522 K528 L529T521-V525 WeakPolarHBondContact O-CA 3.02Å; T521-V525 WeakPolarHBondContact O-CB 3.29Å; T521-V525 WeakPolarHBondContact O-CG2 3.32Å; T521-V525 PolarHBondContact O-N 3.28Å; L522-V525 PolarHBondContact O-N 3Å; V525-K528 PolarHBondContact O-N 2.93Å; V525-L529 VanDerWaalsContact O-CB 3.23Å; V525-L529 WeakPolarHBondContact O-CB 3.49Å; V525-L529 PolarHBondContact O-N 2.59Å
526Q76.8Confident71.7Confident124 Ų124104.2 Ų104.258%0.57951%0.513SS*.Hα-helixtrans-61-48.6168.1-75.8177.1-1000111.1L522 Q523 N524 K528 L529 E530L522-Q526 WeakPolarHBondContact O-CB 3.34Å; L522-Q526 VanDerWaalsContact O-CG 3.31Å; L522-Q526 WeakPolarHBondContact O-CG 3.47Å; L522-Q526 PolarHBondContact O-N 3.24Å; Q523-Q526 PolarHBondContact O-N 3.21Å; N524-Q526 VanDerWaalsContact C-N 3.31Å; Q526-K528 VanDerWaalsContact C-N 3.33Å; Q526-K528 PolarHBondContact O-N 3.03Å; Q526-L529 PolarHBondContact O-N 3.32Å; Q526-E530 WeakPolarHBondContact O-CG 3.35Å; Q526-E530 PolarHBondContact O-N 2.86Å
527G76.9Confident73.1Confident39 Ų39103.3 Ų103.340%0.40251%0.509SS..Hα-helixtrans-58.6-41.1175.500000113.3Q523 N524 E530 M531Q523-G527 PolarHBondContact O-N 3.47Å; N524-G527 CarbonylContact O-C 3.52Å; N524-G527 PolarHBondContact O-N 3.44Å; G527-E530 PolarHBondContact O-N 3.01Å; G527-M531 WeakPolarHBondContact O-CB 3.47Å; G527-M531 PolarHBondContact O-N 3.37Å
528K67.7Low74.1Confident67 Ų6799.4 Ų99.429%0.29149%0.494SS..Hα-helixtrans-65.6-44.3172.6-78.7-172-179.4-159.60112.1Y515 N524 V525 Q526 E530 M531 E532Y515-K528 VanDerWaalsContact CB-CE 3.48Å; Y515-K528 HydrophobicContact CD1-CD 4.35Å; Y515-K528 HydrophobicContact CD1-CG 4.42Å; Y515-K528 HydrophobicContact CD2-CD 4.43Å; Y515-K528 HydrophobicContact CE1-CD 4.37Å; Y515-K528 VanDerWaalsContact CE1-CE 3.41Å; Y515-K528 HydrophobicContact CE1-CG 4.01Å; Y515-K528 HydrophobicContact CE2-CD 4.47Å; Y515-K528 HydrophobicContact CG-CD 4.42Å; N524-K528 WeakPolarHBondContact O-CB 3.48Å; N524-K528 WeakPolarHBondContact O-CG 3.28Å; N524-K528 PolarHBondContact O-N 3.48Å; V525-K528 PolarHBondContact O-N 2.93Å; Q526-K528 VanDerWaalsContact C-N 3.33Å; Q526-K528 PolarHBondContact O-N 3.03Å; K528-E530 PolarHBondContact O-N 3.46Å; K528-M531 PolarHBondContact O-N 2.96Å; K528-E532 VanDerWaalsContact O-CB 3.25Å; K528-E532 WeakPolarHBondContact O-CB 3.46Å; K528-E532 WeakPolarHBondContact O-CG 3.41Å; K528-E532 PolarHBondContact O-N 2.99Å
529L80.6Confident75.6Confident93 Ų9398.7 Ų98.749%0.48749%0.487SS..Hα-helixtrans-60.6-41.4178.2178.963.8000109.2V525 Q526 K533V525-L529 VanDerWaalsContact O-CB 3.23Å; V525-L529 WeakPolarHBondContact O-CB 3.49Å; V525-L529 PolarHBondContact O-N 2.59Å; Q526-L529 PolarHBondContact O-N 3.32Å; L529-K533 HydrophobicContact CD1-CG 4.41Å; L529-K533 HydrophobicContact CG-CD 4.17Å; L529-K533 WeakPolarHBondContact O-CB 3.47Å; L529-K533 WeakPolarHBondContact O-CD 3.27Å; L529-K533 WeakPolarHBondContact O-CG 3.3Å; L529-K533 PolarHBondContact O-N 2.96Å
530E83.6Confident77.1Confident90 Ų9097.4 Ų97.442%0.42148%0.475SS..Hα-helixtrans-67.6-40.4174-67.9-53.8127.300112.6Q526 G527 K528 K533 R534Q526-E530 WeakPolarHBondContact O-CG 3.35Å; Q526-E530 PolarHBondContact O-N 2.86Å; G527-E530 PolarHBondContact O-N 3.01Å; K528-E530 PolarHBondContact O-N 3.46Å; E530-K533 PolarHBondContact O-N 3.3Å; E530-K533 WeakPolarHBondContact OE1-CD 3.46Å; E530-K533 IonicContact OE1-NZ 3.61Å; E530-K533 PolarHBondContact OE1-NZ 3.27Å; E530-R534 WeakPolarHBondContact O-CB 3.37Å; E530-R534 VanDerWaalsContact O-CG 3.25Å; E530-R534 WeakPolarHBondContact O-CG 3.49Å; E530-R534 PolarHBondContact O-N 2.58Å
531M80.8Confident78.4Confident81 Ų8194.7 Ų94.740%0.39946%0.462SS..Hα-helixtrans-66-46.2176.2-172.6-173.5-61.900112.2M511 G527 K528 R534 R535M511-M531 HydrophobicContact CE-SD 4.12Å; M511-M531 HydrophobicContact SD-CE 3.9Å; M511-M531 HydrophobicContact SD-SD 4.03Å; G527-M531 WeakPolarHBondContact O-CB 3.47Å; G527-M531 PolarHBondContact O-N 3.37Å; K528-M531 PolarHBondContact O-N 2.96Å; M531-R534 WeakPolarHBondContact O-CB 3.33Å; M531-R534 PolarHBondContact O-N 3.07Å; M531-R535 WeakPolarHBondContact O-CB 3.13Å; M531-R535 PolarHBondContact O-N 2.79Å
532E82.9Confident79.3Confident83 Ų8394.9 Ų94.939%0.38846%0.461SS..Hα-helixtrans-67-35.9174.7-76.2-60149.700111.2K528 R535 N536K528-E532 VanDerWaalsContact O-CB 3.25Å; K528-E532 WeakPolarHBondContact O-CB 3.46Å; K528-E532 WeakPolarHBondContact O-CG 3.41Å; K528-E532 PolarHBondContact O-N 2.99Å; E532-R535 PolarHBondContact O-N 2.75Å; E532-N536 VanDerWaalsContact O-CB 3.27Å; E532-N536 WeakPolarHBondContact O-CB 3.28Å; E532-N536 PolarHBondContact O-N 3.49Å; E532-N536 PolarHBondContact O-ND2 2.86Å
533K85.5Confident80.3Confident100 Ų10091.3 Ų91.344%0.43545%0.445SS..Hα-helixtrans-62.2-43.9170-81.6169.4-179.31740111.2L529 E530 N536 K537L529-K533 HydrophobicContact CD1-CG 4.41Å; L529-K533 HydrophobicContact CG-CD 4.17Å; L529-K533 WeakPolarHBondContact O-CB 3.47Å; L529-K533 WeakPolarHBondContact O-CD 3.27Å; L529-K533 WeakPolarHBondContact O-CG 3.3Å; L529-K533 PolarHBondContact O-N 2.96Å; E530-K533 PolarHBondContact O-N 3.3Å; E530-K533 WeakPolarHBondContact OE1-CD 3.46Å; E530-K533 IonicContact OE1-NZ 3.61Å; E530-K533 PolarHBondContact OE1-NZ 3.27Å; K533-N536 PolarHBondContact O-N 2.77Å; K533-K537 VanDerWaalsContact O-CB 3.25Å; K533-K537 WeakPolarHBondContact O-CB 3.29Å; K533-K537 PolarHBondContact O-N 3.44Å
534R82.3Confident81.3Confident173 Ų17390.7 Ų90.765%0.65344%0.442SS*.Hα-helixtrans-62.2-44.4175-73.9173.5-172.5-169.91.6111.2E530 M531 K537 A538E530-R534 WeakPolarHBondContact O-CB 3.37Å; E530-R534 VanDerWaalsContact O-CG 3.25Å; E530-R534 WeakPolarHBondContact O-CG 3.49Å; E530-R534 PolarHBondContact O-N 2.58Å; M531-R534 WeakPolarHBondContact O-CB 3.33Å; M531-R534 PolarHBondContact O-N 3.07Å; R534-K537 PolarHBondContact O-N 3.4Å; R534-A538 WeakPolarHBondContact O-CB 3.19Å; R534-A538 PolarHBondContact O-N 3.17Å
535R81.7Confident82Confident155 Ų15590.9 Ų90.959%0.58544%0.443SS*.Hα-helixtrans-61-47.4175.2-174.3-177.5-179.6129.14111.6M531 E532 A538 L539M531-R535 WeakPolarHBondContact O-CB 3.13Å; M531-R535 PolarHBondContact O-N 2.79Å; E532-R535 PolarHBondContact O-N 2.75Å; R535-A538 PolarHBondContact O-N 3.25Å; R535-L539 HydrophobicContact CG-CD1 4.16Å; R535-L539 WeakPolarHBondContact O-CB 3.38Å; R535-L539 VanDerWaalsContact O-CG 3.29Å; R535-L539 WeakPolarHBondContact O-CG 3.25Å; R535-L539 PolarHBondContact O-N 2.61Å
536N86.4Confident82.5Confident80 Ų8091.2 Ų91.243%0.42844%0.441SS..Hα-helixtrans-62.9-43.3177.1-79.2-58.3000111.1E532 K533 A538 L539 E540E532-N536 VanDerWaalsContact O-CB 3.27Å; E532-N536 WeakPolarHBondContact O-CB 3.28Å; E532-N536 PolarHBondContact O-N 3.49Å; E532-N536 PolarHBondContact O-ND2 2.86Å; K533-N536 PolarHBondContact O-N 2.77Å; N536-A538 VanDerWaalsContact C-N 3.33Å; N536-A538 PolarHBondContact O-N 3.17Å; N536-L539 PolarHBondContact O-N 3.45Å; N536-E540 WeakPolarHBondContact O-CB 3.49Å; N536-E540 VanDerWaalsContact O-CG 3.29Å; N536-E540 WeakPolarHBondContact O-CG 3.41Å; N536-E540 PolarHBondContact O-N 2.74Å
537K85.6Confident82.9Confident144 Ų14489 Ų8963%0.62643%0.428SS*.Hα-helixtrans-61.4-40.4174.8-171.8-178.3-179.9-172.20112.1K533 R534 K541K533-K537 VanDerWaalsContact O-CB 3.25Å; K533-K537 WeakPolarHBondContact O-CB 3.29Å; K533-K537 PolarHBondContact O-N 3.44Å; R534-K537 PolarHBondContact O-N 3.4Å; K537-K541 WeakPolarHBondContact O-CB 3.47Å; K537-K541 PolarHBondContact O-N 3.22Å
538A82.5Confident83.3Confident42 Ų4287.9 Ų87.935%0.34742%0.417SS..Hα-helixtrans-64.9-43.7174.500000111.6R534 R535 N536 K541 D542R534-A538 WeakPolarHBondContact O-CB 3.19Å; R534-A538 PolarHBondContact O-N 3.17Å; R535-A538 PolarHBondContact O-N 3.25Å; N536-A538 VanDerWaalsContact C-N 3.33Å; N536-A538 PolarHBondContact O-N 3.17Å; A538-K541 PolarHBondContact O-N 3.02Å; A538-D542 WeakPolarHBondContact O-CB 3.45Å; A538-D542 PolarHBondContact O-N 3.06Å
539L86Confident83.9Confident83 Ų8385.5 Ų85.544%0.43541%0.407SS..Hα-helixtrans-65.4-41176-72.3171.5000112.6R535 N536 K541 D542 V543R535-L539 HydrophobicContact CG-CD1 4.16Å; R535-L539 WeakPolarHBondContact O-CB 3.38Å; R535-L539 VanDerWaalsContact O-CG 3.29Å; R535-L539 WeakPolarHBondContact O-CG 3.25Å; R535-L539 PolarHBondContact O-N 2.61Å; N536-L539 PolarHBondContact O-N 3.45Å; L539-K541 VanDerWaalsContact C-N 3.33Å; L539-D542 PolarHBondContact O-N 2.72Å; L539-V543 WeakPolarHBondContact O-CB 3.25Å; L539-V543 VanDerWaalsContact O-CG2 3.27Å; L539-V543 WeakPolarHBondContact O-CG2 3.45Å; L539-V543 PolarHBondContact O-N 2.92Å
540E86Confident84.1Confident133 Ų13383.9 Ų83.962%0.62140%0.396SS*.Hα-helixtrans-60.2-44.4175-78173.7177.300111.1N536 V543 Q544N536-E540 WeakPolarHBondContact O-CB 3.49Å; N536-E540 VanDerWaalsContact O-CG 3.29Å; N536-E540 WeakPolarHBondContact O-CG 3.41Å; N536-E540 PolarHBondContact O-N 2.74Å; E540-V543 PolarHBondContact O-N 3.19Å; E540-Q544 PolarHBondContact O-N 2.9Å
541K82.8Confident84.2Confident54 Ų5484.7 Ų84.724%0.23540%0.4CS..Hα-helixtrans-64.2-42.9174.2-175.4-176.4173.1-166.60111.6E49 K537 A538 L539 V543 Q544 D545E49-K541 PolarHBondContact O-NZ 3.42Å; K537-K541 WeakPolarHBondContact O-CB 3.47Å; K537-K541 PolarHBondContact O-N 3.22Å; A538-K541 PolarHBondContact O-N 3.02Å; L539-K541 VanDerWaalsContact C-N 3.33Å; K541-V543 VanDerWaalsContact C-N 3.3Å; K541-V543 PolarHBondContact O-N 3.43Å; K541-Q544 WeakPolarHBondContact O-CB 3.34Å; K541-Q544 PolarHBondContact O-N 3.11Å; K541-D545 WeakPolarHBondContact O-CB 3.12Å; K541-D545 VanDerWaalsContact O-CG 3.3Å; K541-D545 PolarHBondContact O-N 2.87Å
542D83.4Confident84.2Confident54 Ų5485.3 Ų85.329%0.28940%0.398SS..Hα-helixtrans-60.8-40.8175.6-92.3-28.4000112.2K51 R327 A538 L539 D545 L546K51-D542 WeakPolarHBondContact CE-OD1 3.21Å; K51-D542 IonicContact NZ-OD1 3.83Å; R327-D542 PolarHBondContact NH2-O 3.41Å; R327-D542 IonicContact NH2-OD1 2.81Å; R327-D542 PolarHBondContact NH2-OD1 2.98Å; A538-D542 WeakPolarHBondContact O-CB 3.45Å; A538-D542 PolarHBondContact O-N 3.06Å; L539-D542 PolarHBondContact O-N 2.72Å; D542-D545 PolarHBondContact O-N 3.14Å; D542-L546 WeakPolarHBondContact O-CB 3.49Å; D542-L546 VanDerWaalsContact O-CG 3.25Å; D542-L546 WeakPolarHBondContact O-CG 3.46Å; D542-L546 PolarHBondContact O-N 2.65Å
543V87.1Confident84.1Confident54 Ų5484.7 Ų84.733%0.32740%0.395SS..Hα-helixtrans-62.2-47173.8167.60000110.5L539 E540 K541 D545 L546 Y547L539-V543 WeakPolarHBondContact O-CB 3.25Å; L539-V543 VanDerWaalsContact O-CG2 3.27Å; L539-V543 WeakPolarHBondContact O-CG2 3.45Å; L539-V543 PolarHBondContact O-N 2.92Å; E540-V543 PolarHBondContact O-N 3.19Å; K541-V543 VanDerWaalsContact C-N 3.3Å; K541-V543 PolarHBondContact O-N 3.43Å; V543-D545 VanDerWaalsContact C-N 3.29Å; V543-D545 PolarHBondContact O-N 2.92Å; V543-L546 WeakPolarHBondContact O-CB 3.27Å; V543-L546 PolarHBondContact O-N 2.93Å; V543-Y547 HydrophobicContact CG1-CD2 3.64Å; V543-Y547 HydrophobicContact CG1-CE2 3.39Å; V543-Y547 WeakPolarHBondContact O-CD2 3.5Å; V543-Y547 PolarHBondContact O-N 3.04Å
544Q86.6Confident84Confident140 Ų14084.3 Ų84.365%0.65439%0.391SS*.Hα-helixtrans-58.2-42.5175.8-176.4178-0.100111.8E540 K541 Y547 G548E540-Q544 PolarHBondContact O-N 2.9Å; K541-Q544 WeakPolarHBondContact O-CB 3.34Å; K541-Q544 PolarHBondContact O-N 3.11Å; Q544-Y547 WeakPolarHBondContact O-CB 3.45Å; Q544-Y547 PolarHBondContact O-N 3.02Å; Q544-G548 PolarHBondContact O-N 3.23Å
545D82.9Confident84Confident37 Ų3779.9 Ų79.920%0.19838%0.377CS..Hα-helixtrans-68.4-38177.9-72-27.6000112.2K51 R327 K541 D542 V543 Y547 G548 E549K51-D545 WeakPolarHBondContact CE-OD2 3.24Å; K51-D545 IonicContact NZ-OD2 3.06Å; K51-D545 PolarHBondContact NZ-OD2 2.92Å; R327-D545 VanDerWaalsContact NH2-CB 3.29Å; K541-D545 WeakPolarHBondContact O-CB 3.12Å; K541-D545 VanDerWaalsContact O-CG 3.3Å; K541-D545 PolarHBondContact O-N 2.87Å; D542-D545 PolarHBondContact O-N 3.14Å; V543-D545 VanDerWaalsContact C-N 3.29Å; V543-D545 PolarHBondContact O-N 2.92Å; D545-Y547 VanDerWaalsContact C-N 3.33Å; D545-G548 PolarHBondContact O-N 2.68Å; D545-E549 WeakPolarHBondContact O-CB 3.42Å; D545-E549 WeakPolarHBondContact O-CG 3Å; D545-E549 PolarHBondContact O-N 3.49Å
546L84.7Confident83.9Confident89 Ų8974.2 Ų74.247%0.46636%0.359SS..Hα-helixtrans-63.1-40.7172.7-75.4168.7000111.2D542 V543 E549 F550D542-L546 WeakPolarHBondContact O-CB 3.49Å; D542-L546 VanDerWaalsContact O-CG 3.25Å; D542-L546 WeakPolarHBondContact O-CG 3.46Å; D542-L546 PolarHBondContact O-N 2.65Å; V543-L546 WeakPolarHBondContact O-CB 3.27Å; V543-L546 PolarHBondContact O-N 2.93Å; L546-E549 PolarHBondContact O-N 2.86Å; L546-F550 VanDerWaalsContact O-CB 3.25Å; L546-F550 WeakPolarHBondContact O-CB 3.45Å; L546-F550 PolarHBondContact O-N 2.82Å
547Y86Confident83.6Confident77 Ų7773.7 Ų73.730%0.30235%0.351SS..Hα-helixtrans-61.3-45.9171.9-82.7-68.6000111.3V543 Q544 D545 E549 F550 E551 P711V543-Y547 HydrophobicContact CG1-CD2 3.64Å; V543-Y547 HydrophobicContact CG1-CE2 3.39Å; V543-Y547 WeakPolarHBondContact O-CD2 3.5Å; V543-Y547 PolarHBondContact O-N 3.04Å; Q544-Y547 WeakPolarHBondContact O-CB 3.45Å; Q544-Y547 PolarHBondContact O-N 3.02Å; D545-Y547 VanDerWaalsContact C-N 3.33Å; Y547-E549 PolarHBondContact O-N 3.23Å; Y547-F550 PolarHBondContact O-N 3.47Å; Y547-E551 WeakPolarHBondContact O-CB 3.25Å; Y547-E551 WeakPolarHBondContact O-CG 3.29Å; Y547-E551 PolarHBondContact O-N 2.86Å; Y547-P711 HydrophobicContact CE1-CB 3.83Å; Y547-P711 HydrophobicContact CE1-CG 4.22Å
548G83.7Confident83.6Confident17 Ų1768.5 Ų68.518%0.17533%0.33CS..Hα-helixtrans-60.4-44176.200000112.9Q544 D545 E551 R552Q544-G548 PolarHBondContact O-N 3.23Å; D545-G548 PolarHBondContact O-N 2.68Å; G548-E551 PolarHBondContact O-N 3.49Å; G548-R552 VanDerWaalsContact C-NH1 3.28Å; G548-R552 WeakPolarHBondContact O-CG 3.44Å; G548-R552 PolarHBondContact O-N 2.85Å; G548-R552 PolarHBondContact O-NH1 3.4Å
549E81.8Confident83.6Confident17 Ų1769.2 Ų69.28%0.07933%0.328CS..Hα-helixtrans-61-44175.1-81.3178.3-169.300112.1R246 L323 R327 D545 L546 Y547 R552 E553R246-E549 PolarHBondContact NH1-O 2.94Å; R246-E549 PolarHBondContact NH2-O 3.15Å; L323-E549 WeakPolarHBondContact CD2-OE1 3.27Å; R327-E549 IonicContact CZ-OE1 2.62Å; R327-E549 IonicContact CZ-OE2 3.36Å; R327-E549 IonicContact NE-OE1 3.41Å; R327-E549 IonicContact NH1-OE1 3.87Å; R327-E549 PolarHBondContact NH1-OE1 2.92Å; R327-E549 IonicContact NH1-OE2 2.67Å; R327-E549 PolarHBondContact NH1-OE2 2.8Å; D545-E549 WeakPolarHBondContact O-CB 3.42Å; D545-E549 WeakPolarHBondContact O-CG 3Å; D545-E549 PolarHBondContact O-N 3.49Å; L546-E549 PolarHBondContact O-N 2.86Å; Y547-E549 PolarHBondContact O-N 3.23Å; E549-R552 VanDerWaalsContact CG-NH2 3.32Å; E549-R552 PolarHBondContact O-N 3.45Å; E549-E553 WeakPolarHBondContact O-CB 3.17Å; E549-E553 PolarHBondContact O-N 3.37Å
550F84.6Confident83.3Confident58 Ų5866.3 Ų66.325%0.25431%0.314SS..Hα-helixtrans-65-41.4177.8-179-99.1000111.8L546 Y547 E553 R554 F709 P711L546-F550 VanDerWaalsContact O-CB 3.25Å; L546-F550 WeakPolarHBondContact O-CB 3.45Å; L546-F550 PolarHBondContact O-N 2.82Å; Y547-F550 PolarHBondContact O-N 3.47Å; F550-E553 PolarHBondContact O-N 2.96Å; F550-R554 WeakPolarHBondContact O-CB 2.98Å; F550-R554 PolarHBondContact O-N 2.97Å; F550-F709 HydrophobicContact CE2-CD1 4.25Å; F550-F709 HydrophobicContact CZ-CB 3.86Å; F550-F709 HydrophobicContact CZ-CD1 4.2Å; F550-F709 VanDerWaalsContact CZ-O 3.32Å; F550-F709 WeakPolarHBondContact CZ-O 3.27Å; F550-P711 HydrophobicContact CE1-CB 4.49Å; F550-P711 HydrophobicContact CE1-CG 4.4Å
551E84.5Confident83.2Confident107 Ų10762.2 Ų62.250%0.530%0.296SS..Hα-helixtrans-63.6-41.5175.4-75-169.4151.400112.1Y547 G548 R554 Q555Y547-E551 WeakPolarHBondContact O-CB 3.25Å; Y547-E551 WeakPolarHBondContact O-CG 3.29Å; Y547-E551 PolarHBondContact O-N 2.86Å; G548-E551 PolarHBondContact O-N 3.49Å; E551-R554 PolarHBondContact O-N 3.41Å; E551-R554 IonicContact OE1-NH2 2.88Å; E551-Q555 WeakPolarHBondContact O-CB 3.36Å; E551-Q555 PolarHBondContact O-N 3.35Å
552R81.5Confident83.3Confident94 Ų9464.6 Ų64.636%0.35530%0.303SS..Hα-helixtrans-62.8-45.5174-72.8-171.2-66.8-8110.7111.4E320 G548 E549 Q555 D556E320-R552 IonicContact OE1-NH2 2.76Å; E320-R552 IonicContact OE2-CZ 2.67Å; E320-R552 IonicContact OE2-NE 3.71Å; E320-R552 PolarHBondContact OE2-NE 2.92Å; E320-R552 IonicContact OE2-NH2 3.58Å; E320-R552 PolarHBondContact OE2-NH2 3.33Å; G548-R552 VanDerWaalsContact C-NH1 3.28Å; G548-R552 WeakPolarHBondContact O-CG 3.44Å; G548-R552 PolarHBondContact O-N 2.85Å; G548-R552 PolarHBondContact O-NH1 3.4Å; E549-R552 VanDerWaalsContact CG-NH2 3.32Å; E549-R552 PolarHBondContact O-N 3.45Å; R552-Q555 PolarHBondContact O-N 3.16Å; R552-D556 PolarHBondContact O-N 2.91Å
553E80.7Confident83.3Confident71 Ų7166.1 Ų66.133%0.33231%0.307SS..Hα-helixtrans-65.4-42.7179.3-163.3-170.5168.400111.3R246 E549 F550 Q555 D556 Y557R246-E553 VanDerWaalsContact NH1-N 3.17Å; E549-E553 WeakPolarHBondContact O-CB 3.17Å; E549-E553 PolarHBondContact O-N 3.37Å; F550-E553 PolarHBondContact O-N 2.96Å; E553-Q555 VanDerWaalsContact C-N 3.31Å; E553-Q555 PolarHBondContact O-N 3.2Å; E553-D556 WeakPolarHBondContact O-CB 3.03Å; E553-D556 PolarHBondContact O-N 3.26Å; E553-Y557 HydrophobicContact CG-CD2 4.16Å; E553-Y557 HydrophobicContact CG-CE2 3.53Å; E553-Y557 WeakPolarHBondContact O-CD2 3.12Å; E553-Y557 PolarHBondContact O-N 3.4Å; E553-Y557 VanDerWaalsContact OE1-CE2 3.25Å; E553-Y557 WeakPolarHBondContact OE1-CE2 3.24Å; E553-Y557 PolarHBondContact OE1-OH 2.95Å
554R83Confident83.1Confident91 Ų9166.8 Ų66.834%0.34331%0.307SS..Hα-helixtrans-58.5-43.6173.3-176.2-174.768.7-169.6-5.1111.3F550 E551 Y557 L558F550-R554 WeakPolarHBondContact O-CB 2.98Å; F550-R554 PolarHBondContact O-N 2.97Å; E551-R554 PolarHBondContact O-N 3.41Å; E551-R554 IonicContact OE1-NH2 2.88Å; R554-Y557 PolarHBondContact O-N 3.27Å; R554-L558 HydrophobicContact CG-CD1 4.26Å; R554-L558 VanDerWaalsContact O-CG 3.29Å; R554-L558 WeakPolarHBondContact O-CG 3.34Å; R554-L558 PolarHBondContact O-N 3.24Å
555Q82.3Confident83.1Confident80 Ų8063.4 Ų63.437%0.37429%0.293SS..Hα-helixtrans-62.6-43.8176.9-17764.637.200111.2E551 R552 E553 Y557 L558 D559 R562E551-Q555 WeakPolarHBondContact O-CB 3.36Å; E551-Q555 PolarHBondContact O-N 3.35Å; R552-Q555 PolarHBondContact O-N 3.16Å; E553-Q555 VanDerWaalsContact C-N 3.31Å; E553-Q555 PolarHBondContact O-N 3.2Å; Q555-Y557 VanDerWaalsContact C-N 3.32Å; Q555-Y557 PolarHBondContact O-N 3.01Å; Q555-L558 PolarHBondContact O-N 2.93Å; Q555-L558 VanDerWaalsContact O-N 3.16Å; Q555-D559 PolarHBondContact NE2-OD1 3.33Å; Q555-D559 VanDerWaalsContact NE2-OD1 3.11Å; Q555-D559 PolarHBondContact NE2-OD2 3.08Å; Q555-D559 VanDerWaalsContact NE2-OD2 3.16Å; Q555-D559 PolarHBondContact O-N 3.41Å; Q555-R562 VanDerWaalsContact NE2-NH1 3.19Å
556D79.7Confident83.2Confident36 Ų3664.1 Ų64.119%0.19330%0.295CS..Hα-helixtrans-59.3-42.2176.2-72.1-16.5000111.8R246 S248 R552 E553 D559 T560R246-D556 WeakPolarHBondContact CD-OD2 3.39Å; S248-D556 VanDerWaalsContact CB-OD1 3.23Å; S248-D556 WeakPolarHBondContact CB-OD1 3.48Å; S248-D556 PolarHBondContact OG-OD1 3.35Å; S248-D556 PolarHBondContact OG-OD2 3.24Å; S248-D556 VanDerWaalsContact OG-OD2 3.08Å; R552-D556 PolarHBondContact O-N 2.91Å; E553-D556 WeakPolarHBondContact O-CB 3.03Å; E553-D556 PolarHBondContact O-N 3.26Å; D556-D559 PolarHBondContact O-N 3.35Å; D556-T560 PolarHBondContact O-N 3.05Å; D556-T560 PolarHBondContact O-OG1 2.81Å
557Y80.8Confident83.2Confident69 Ų6961.9 Ų61.927%0.27128%0.283SS..Hα-helixtrans-64.4-44.8173.7-70.3-51000112.1S268 E553 R554 Q555 D559 T560 I561 F709S268-Y557 PolarHBondContact OG-OH 3.41Å; E553-Y557 HydrophobicContact CG-CD2 4.16Å; E553-Y557 HydrophobicContact CG-CE2 3.53Å; E553-Y557 WeakPolarHBondContact O-CD2 3.12Å; E553-Y557 PolarHBondContact O-N 3.4Å; E553-Y557 VanDerWaalsContact OE1-CE2 3.25Å; E553-Y557 WeakPolarHBondContact OE1-CE2 3.24Å; E553-Y557 PolarHBondContact OE1-OH 2.95Å; R554-Y557 PolarHBondContact O-N 3.27Å; Q555-Y557 VanDerWaalsContact C-N 3.32Å; Q555-Y557 PolarHBondContact O-N 3.01Å; Y557-D559 VanDerWaalsContact C-N 3.33Å; Y557-D559 PolarHBondContact O-N 3.37Å; Y557-T560 WeakPolarHBondContact O-CB 3.5Å; Y557-T560 PolarHBondContact O-N 3.48Å; Y557-I561 VanDerWaalsContact O-CG1 3.26Å; Y557-I561 WeakPolarHBondContact O-CG1 3.41Å; Y557-I561 PolarHBondContact O-N 3.39Å; Y557-F709 HydrophobicContact CD2-CE1 4.07Å; Y557-F709 HydrophobicContact CD2-CE2 4.43Å; Y557-F709 AromaticContact CD2-CZ 3.78Å; Y557-F709 HydrophobicContact CD2-CZ 3.78Å; Y557-F709 HydrophobicContact CE2-CE1 4.11Å; Y557-F709 HydrophobicContact CE2-CZ 4.09Å; Y557-F709 HydrophobicContact CG-CZ 4.37Å
558L85Confident83.3Confident36 Ų3663.6 Ų63.619%0.18830%0.296CS..Hα-helixtrans-62-40.5177.8-72.4173000111.9R554 Q555 T560 I561 R562R554-L558 HydrophobicContact CG-CD1 4.26Å; R554-L558 VanDerWaalsContact O-CG 3.29Å; R554-L558 WeakPolarHBondContact O-CG 3.34Å; R554-L558 PolarHBondContact O-N 3.24Å; Q555-L558 PolarHBondContact O-N 2.93Å; Q555-L558 VanDerWaalsContact O-N 3.16Å; L558-T560 VanDerWaalsContact C-N 3.33Å; L558-I561 PolarHBondContact O-N 2.82Å; L558-R562 WeakPolarHBondContact O-CB 3.48Å; L558-R562 VanDerWaalsContact O-CG 3.28Å; L558-R562 WeakPolarHBondContact O-CG 3.36Å; L558-R562 PolarHBondContact O-N 2.84Å
559D82.6Confident83.6Confident56 Ų5666.2 Ų66.230%0.29930%0.303SS..Hα-helixtrans-67.3-36.4177.1-71.7-26.6000111.8Q555 D556 Y557 R562 K563Q555-D559 PolarHBondContact NE2-OD1 3.33Å; Q555-D559 VanDerWaalsContact NE2-OD1 3.11Å; Q555-D559 PolarHBondContact NE2-OD2 3.08Å; Q555-D559 VanDerWaalsContact NE2-OD2 3.16Å; Q555-D559 PolarHBondContact O-N 3.41Å; D556-D559 PolarHBondContact O-N 3.35Å; Y557-D559 VanDerWaalsContact C-N 3.33Å; Y557-D559 PolarHBondContact O-N 3.37Å; D559-R562 PolarHBondContact O-N 2.85Å; D559-R562 IonicContact OD1-CZ 2.7Å; D559-R562 IonicContact OD1-NH1 3.04Å; D559-R562 PolarHBondContact OD1-NH1 2.77Å; D559-K563 VanDerWaalsContact O-CG 3.32Å; D559-K563 WeakPolarHBondContact O-CG 3.46Å; D559-K563 PolarHBondContact O-N 3.32Å
560T79.1Confident83.9Confident22 Ų2266.3 Ų66.314%0.13530%0.304CS..Hα-helixtrans-63-47.3171.8-57.70000111.1T261 D556 Y557 L558 R562 K563 Q564T261-T560 HydrophobicContact CG2-CG2 4.12Å; T261-T560 WeakPolarHBondContact OG1-CG2 3.45Å; D556-T560 PolarHBondContact O-N 3.05Å; D556-T560 PolarHBondContact O-OG1 2.81Å; Y557-T560 WeakPolarHBondContact O-CB 3.5Å; Y557-T560 PolarHBondContact O-N 3.48Å; L558-T560 VanDerWaalsContact C-N 3.33Å; T560-R562 PolarHBondContact O-N 2.89Å; T560-K563 PolarHBondContact O-N 3.49Å; T560-Q564 WeakPolarHBondContact O-CB 3.24Å; T560-Q564 WeakPolarHBondContact O-CG 3.4Å; T560-Q564 PolarHBondContact O-N 3.29Å
561I83.5Confident84.1Confident47 Ų4767.4 Ų67.424%0.24131%0.312CS..Hα-helixtrans-60.5-45177.7-69163.9000110.6Y557 L558 K563 Q564 N565 A705Y557-I561 VanDerWaalsContact O-CG1 3.26Å; Y557-I561 WeakPolarHBondContact O-CG1 3.41Å; Y557-I561 PolarHBondContact O-N 3.39Å; L558-I561 PolarHBondContact O-N 2.82Å; I561-K563 PolarHBondContact O-N 3.26Å; I561-Q564 PolarHBondContact O-N 2.9Å; I561-N565 WeakPolarHBondContact O-CB 3.24Å; I561-N565 VanDerWaalsContact O-CG 3.26Å; I561-N565 PolarHBondContact O-N 2.89Å; I561-N565 PolarHBondContact O-ND2 3.39Å; I561-A705 HydrophobicContact CD1-CB 4.21Å
562R85.7Confident84.4Confident104 Ų10465.3 Ų65.339%0.39231%0.309SS..Hα-helixtrans-58.4-48.6176.7-74173.2-171.4143.81.1111.5Q555 L558 D559 T560 Q564 N565 Q566Q555-R562 VanDerWaalsContact NE2-NH1 3.19Å; L558-R562 WeakPolarHBondContact O-CB 3.48Å; L558-R562 VanDerWaalsContact O-CG 3.28Å; L558-R562 WeakPolarHBondContact O-CG 3.36Å; L558-R562 PolarHBondContact O-N 2.84Å; D559-R562 PolarHBondContact O-N 2.85Å; D559-R562 IonicContact OD1-CZ 2.7Å; D559-R562 IonicContact OD1-NH1 3.04Å; D559-R562 PolarHBondContact OD1-NH1 2.77Å; T560-R562 PolarHBondContact O-N 2.89Å; R562-Q564 PolarHBondContact O-N 3.03Å; R562-N565 PolarHBondContact O-N 3.22Å; R562-Q566 VanDerWaalsContact O-CG 3.29Å; R562-Q566 WeakPolarHBondContact O-CG 3.19Å; R562-Q566 PolarHBondContact O-N 2.86Å
563K82.8Confident84.8Confident86 Ų8662.7 Ų62.737%0.37430%0.301SS..Hα-helixtrans-64-38.6178.6-71.6177.3-174.6176.80112.4L257 D559 T560 I561 Q566 Q567L257-K563 HydrophobicContact CD1-CD 4.48Å; L257-K563 HydrophobicContact CD2-CB 3.58Å; L257-K563 HydrophobicContact CD2-CD 3.45Å; L257-K563 VanDerWaalsContact CD2-CD 3.45Å; L257-K563 HydrophobicContact CD2-CG 4.16Å; D559-K563 VanDerWaalsContact O-CG 3.32Å; D559-K563 WeakPolarHBondContact O-CG 3.46Å; D559-K563 PolarHBondContact O-N 3.32Å; T560-K563 PolarHBondContact O-N 3.49Å; I561-K563 PolarHBondContact O-N 3.26Å; K563-Q566 WeakPolarHBondContact O-CB 3.43Å; K563-Q566 PolarHBondContact O-N 3.41Å; K563-Q567 WeakPolarHBondContact O-CG 3.36Å; K563-Q567 PolarHBondContact O-N 3.41Å
564Q82.7Confident85.1Confident68 Ų6859.7 Ų59.732%0.31829%0.287SS..Hα-helixtrans-66.8-43.1175.3-73.7176.9-10.100111.8T560 I561 R562 Q566 Q567 L568T560-Q564 WeakPolarHBondContact O-CB 3.24Å; T560-Q564 WeakPolarHBondContact O-CG 3.4Å; T560-Q564 PolarHBondContact O-N 3.29Å; I561-Q564 PolarHBondContact O-N 2.9Å; R562-Q564 PolarHBondContact O-N 3.03Å; Q564-Q566 VanDerWaalsContact C-N 3.3Å; Q564-Q566 PolarHBondContact O-N 3.3Å; Q564-Q567 WeakPolarHBondContact O-CB 3.23Å; Q564-Q567 PolarHBondContact O-N 3.35Å; Q564-Q567 VanDerWaalsContact O-N 3.11Å; Q564-L568 WeakPolarHBondContact O-CG 3.24Å; Q564-L568 PolarHBondContact O-N 3.35Å
565N86.9Confident85.2Confident69 Ų6961.2 Ų61.237%0.36930%0.302SS..Hα-helixtrans-61.4-39.3174.8-74.3-17.9000111.6I561 R562 L568 K569I561-N565 WeakPolarHBondContact O-CB 3.24Å; I561-N565 VanDerWaalsContact O-CG 3.26Å; I561-N565 PolarHBondContact O-N 2.89Å; I561-N565 PolarHBondContact O-ND2 3.39Å; R562-N565 PolarHBondContact O-N 3.22Å; N565-L568 PolarHBondContact O-N 3.28Å; N565-K569 WeakPolarHBondContact O-CB 3.46Å; N565-K569 PolarHBondContact O-N 2.86Å
566Q86.6Confident85.4Confident52 Ų5262.7 Ų62.724%0.24331%0.312CS..Hα-helixtrans-58.8-48.1171.1-71.8170.6-5.900111.1R562 K563 Q564 K569 L570 W600 W607R562-Q566 VanDerWaalsContact O-CG 3.29Å; R562-Q566 WeakPolarHBondContact O-CG 3.19Å; R562-Q566 PolarHBondContact O-N 2.86Å; K563-Q566 WeakPolarHBondContact O-CB 3.43Å; K563-Q566 PolarHBondContact O-N 3.41Å; Q564-Q566 VanDerWaalsContact C-N 3.3Å; Q564-Q566 PolarHBondContact O-N 3.3Å; Q566-K569 WeakPolarHBondContact O-CB 3.23Å; Q566-K569 PolarHBondContact O-N 3.39Å; Q566-L570 PolarHBondContact O-N 3.41Å; Q566-W600 HydrophobicContact CB-CE3 4.33Å; Q566-W600 HydrophobicContact CB-CH2 4.49Å; Q566-W600 HydrophobicContact CB-CZ3 4.25Å; Q566-W600 HydrophobicContact CG-CD2 3.98Å; Q566-W600 HydrophobicContact CG-CE3 4Å; Q566-W600 HydrophobicContact CG-CH2 3.66Å; Q566-W600 HydrophobicContact CG-CZ2 3.67Å; Q566-W600 HydrophobicContact CG-CZ3 3.84Å; Q566-W607 HydrophobicContact CB-CZ2 4.14Å; Q566-W607 PolarHBondContact O-NE1 2.6Å
567Q84.1Confident85.6Confident42 Ų4265.9 Ų65.920%0.19632%0.324CS..Hα-helixtrans-62.8-42.9178.2-73.1-178.9-13.700113.1K563 Q564 K569 L570 L571K563-Q567 WeakPolarHBondContact O-CG 3.36Å; K563-Q567 PolarHBondContact O-N 3.41Å; Q564-Q567 WeakPolarHBondContact O-CB 3.23Å; Q564-Q567 PolarHBondContact O-N 3.35Å; Q564-Q567 VanDerWaalsContact O-N 3.11Å; Q567-K569 VanDerWaalsContact C-N 3.26Å; Q567-K569 PolarHBondContact O-N 2.85Å; Q567-L570 WeakPolarHBondContact O-CB 3.4Å; Q567-L570 PolarHBondContact O-N 2.75Å; Q567-L571 WeakPolarHBondContact O-CG 3.28Å; Q567-L571 PolarHBondContact O-N 3.21Å
568L87.7Confident85.6Confident113 Ų11364.6 Ų64.659%0.59232%0.323SS*.Hα-helixtrans-60-40.8174.8-73.4173.5000111Q564 N565 L571 S572Q564-L568 WeakPolarHBondContact O-CG 3.24Å; Q564-L568 PolarHBondContact O-N 3.35Å; N565-L568 PolarHBondContact O-N 3.28Å; L568-L571 PolarHBondContact O-N 3.15Å; L568-S572 WeakPolarHBondContact O-CB 3.49Å; L568-S572 PolarHBondContact O-N 2.78Å
569K90Very high85.3Confident73 Ų7370.6 Ų70.632%0.31735%0.348SS..Hα-helixtrans-64.9-41.3176.5-165.2164.8-170.8176.90112.4N565 Q566 Q567 L571 S572 Q573 W600 Q605 N606N565-K569 WeakPolarHBondContact O-CB 3.46Å; N565-K569 PolarHBondContact O-N 2.86Å; Q566-K569 WeakPolarHBondContact O-CB 3.23Å; Q566-K569 PolarHBondContact O-N 3.39Å; Q567-K569 VanDerWaalsContact C-N 3.26Å; Q567-K569 PolarHBondContact O-N 2.85Å; K569-L571 PolarHBondContact O-N 2.8Å; K569-S572 WeakPolarHBondContact O-CB 3.38Å; K569-S572 PolarHBondContact O-N 3.46Å; K569-Q573 WeakPolarHBondContact O-CG 3.44Å; K569-Q573 PolarHBondContact O-N 3.43Å; K569-W600 HydrophobicContact CD-CH2 4.44Å; K569-W600 HydrophobicContact CD-CZ3 4.29Å; K569-Q605 WeakPolarHBondContact CD-O 3.48Å; K569-Q605 VanDerWaalsContact CE-O 3.27Å; K569-Q605 WeakPolarHBondContact CE-O 3.16Å; K569-Q605 PolarHBondContact NZ-O 2.82Å; K569-N606 WeakPolarHBondContact CE-OD1 3.41Å; K569-N606 PolarHBondContact NZ-OD1 3.04Å
570L89.1Confident84.9Confident19 Ų1972.5 Ų72.510%0.09936%0.363CS..Hα-helixtrans-57-50.3173.3-179.960.1000111Q566 Q567 S572 Q573 L574 Q595 A598 W607 L609Q566-L570 PolarHBondContact O-N 3.41Å; Q567-L570 WeakPolarHBondContact O-CB 3.4Å; Q567-L570 PolarHBondContact O-N 2.75Å; L570-S572 VanDerWaalsContact C-N 3.33Å; L570-S572 PolarHBondContact O-N 2.67Å; L570-Q573 PolarHBondContact O-N 2.61Å; L570-L574 HydrophobicContact CD1-CD1 4.29Å; L570-L574 HydrophobicContact CD1-CG 4.35Å; L570-L574 HydrophobicContact CG-CD1 4.05Å; L570-L574 WeakPolarHBondContact O-CB 3.49Å; L570-L574 VanDerWaalsContact O-CG 3.31Å; L570-L574 WeakPolarHBondContact O-CG 3Å; L570-L574 PolarHBondContact O-N 3.42Å; L570-Q595 HydrophobicContact CD2-CG 4.49Å; L570-A598 HydrophobicContact CD1-CB 3.76Å; L570-W607 HydrophobicContact CB-CD2 4.06Å; L570-W607 HydrophobicContact CB-CG 3.98Å; L570-W607 HydrophobicContact CB-CZ2 4.38Å; L570-W607 HydrophobicContact CD1-CB 3.88Å; L570-W607 HydrophobicContact CD1-CD2 3.76Å; L570-W607 HydrophobicContact CD1-CE3 4.08Å; L570-W607 HydrophobicContact CD1-CG 3.66Å; L570-W607 HydrophobicContact CD2-CD2 4.4Å; L570-W607 HydrophobicContact CD2-CH2 4.48Å; L570-W607 HydrophobicContact CD2-CZ2 4.36Å; L570-W607 HydrophobicContact CG-CD2 4.29Å; L570-W607 HydrophobicContact CG-CG 4.37Å; L570-L609 HydrophobicContact CD1-CD2 3.66Å
571L88.3Confident84.4Confident80 Ų8072.3 Ų72.342%0.41936%0.363SS..Hα-helixtrans-62.9-40.1-180-69.4172000112Q567 L568 K569 L574 L575Q567-L571 WeakPolarHBondContact O-CG 3.28Å; Q567-L571 PolarHBondContact O-N 3.21Å; L568-L571 PolarHBondContact O-N 3.15Å; K569-L571 PolarHBondContact O-N 2.8Å; L571-L574 PolarHBondContact O-N 3.08Å; L571-L575 WeakPolarHBondContact O-CG 3.37Å; L571-L575 PolarHBondContact O-N 3.21Å
572S90.2Very high83.5Confident64 Ų6476.5 Ų76.545%0.44838%0.384SS..Hα-helixtrans-60.1-49.5173.9-169.10000111.5L568 K569 L570 L574 L575 D576L568-S572 WeakPolarHBondContact O-CB 3.49Å; L568-S572 PolarHBondContact O-N 2.78Å; K569-S572 WeakPolarHBondContact O-CB 3.38Å; K569-S572 PolarHBondContact O-N 3.46Å; L570-S572 VanDerWaalsContact C-N 3.33Å; L570-S572 PolarHBondContact O-N 2.67Å; S572-L574 VanDerWaalsContact C-N 3.31Å; S572-L574 PolarHBondContact O-N 3.33Å; S572-L575 PolarHBondContact O-N 3.34Å; S572-D576 PolarHBondContact O-N 3.35Å
573Q90.3Very high82.2Confident39 Ų3977 Ų7718%0.18240%0.401CS..Hα-helixtrans-65.4-34.5179.1-69.5177.5-63.400112.1K569 L570 K577 W607 L609K569-Q573 WeakPolarHBondContact O-CG 3.44Å; K569-Q573 PolarHBondContact O-N 3.43Å; L570-Q573 PolarHBondContact O-N 2.61Å; Q573-K577 VanDerWaalsContact O-CG 3.29Å; Q573-K577 WeakPolarHBondContact O-CG 3.39Å; Q573-K577 PolarHBondContact O-N 3.12Å; Q573-W607 PolarHBondContact NE2-O 3.3Å; Q573-L609 HydrophobicContact CB-CD1 3.67Å
574L87.4Confident81.1Confident7 Ų780.3 Ų80.34%0.03741%0.411CS..Hα-helixtrans-65.4-46.3173.1-75172.1000111.5L570 L571 S572 D576 K577 V578 Y588 V594 Q595 L609L570-L574 HydrophobicContact CD1-CD1 4.29Å; L570-L574 HydrophobicContact CD1-CG 4.35Å; L570-L574 HydrophobicContact CG-CD1 4.05Å; L570-L574 WeakPolarHBondContact O-CB 3.49Å; L570-L574 VanDerWaalsContact O-CG 3.31Å; L570-L574 WeakPolarHBondContact O-CG 3Å; L570-L574 PolarHBondContact O-N 3.42Å; L571-L574 PolarHBondContact O-N 3.08Å; S572-L574 VanDerWaalsContact C-N 3.31Å; S572-L574 PolarHBondContact O-N 3.33Å; L574-D576 VanDerWaalsContact C-N 3.31Å; L574-D576 PolarHBondContact O-N 3.48Å; L574-K577 PolarHBondContact O-N 2.73Å; L574-K577 VanDerWaalsContact O-N 3.16Å; L574-V578 WeakPolarHBondContact O-CB 3.48Å; L574-V578 WeakPolarHBondContact O-CG2 3.39Å; L574-V578 PolarHBondContact O-N 3.18Å; L574-Y588 HydrophobicContact CD2-CD1 4.5Å; L574-Y588 HydrophobicContact CD2-CE1 4.07Å; L574-V594 HydrophobicContact CD2-CB 4.41Å; L574-V594 HydrophobicContact CD2-CG1 3.55Å; L574-Q595 HydrophobicContact CD1-CG 3.75Å; L574-L609 HydrophobicContact CD2-CD1 4.25Å; L574-L609 HydrophobicContact CD2-CD2 3.88Å; L574-L609 HydrophobicContact CG-CD2 4.32Å
575L84.8Confident80.5Confident124 Ų12481.3 Ų81.365%0.64942%0.419SS*.Hα-helixtrans-57.5-44.5176.2-81.3166.7000111.7L571 S572 K577 V578 K579L571-L575 WeakPolarHBondContact O-CG 3.37Å; L571-L575 PolarHBondContact O-N 3.21Å; S572-L575 PolarHBondContact O-N 3.34Å; L575-K577 VanDerWaalsContact C-N 3.3Å; L575-K577 PolarHBondContact O-N 3.02Å; L575-V578 PolarHBondContact O-N 3.44Å; L575-K579 WeakPolarHBondContact O-CB 3.29Å; L575-K579 PolarHBondContact O-N 2.87Å
576D86.3Confident80.1Confident111 Ų11178.6 Ų78.659%0.59441%0.405SS*.Hα-helixtrans-60.7-37.7177.3-70.5-25.2000112.5S572 L574 P580S572-D576 PolarHBondContact O-N 3.35Å; L574-D576 VanDerWaalsContact C-N 3.31Å; L574-D576 PolarHBondContact O-N 3.48Å; D576-P580 WeakPolarHBondContact O-CD 3.25Å
577K83.1Confident79.8Confident103 Ų10378.6 Ų78.645%0.44841%0.407SS..Hα-helixtrans-79.8-31.9179-67.9-69.2-176.2179.40113.5Q573 L574 L575 P580 C581 Y588 L609Q573-K577 VanDerWaalsContact O-CG 3.29Å; Q573-K577 WeakPolarHBondContact O-CG 3.39Å; Q573-K577 PolarHBondContact O-N 3.12Å; L574-K577 PolarHBondContact O-N 2.73Å; L574-K577 VanDerWaalsContact O-N 3.16Å; L575-K577 VanDerWaalsContact C-N 3.3Å; L575-K577 PolarHBondContact O-N 3.02Å; K577-P580 WeakPolarHBondContact O-CD 3.45Å; K577-P580 WeakPolarHBondContact O-CG 3.4Å; K577-C581 PolarHBondContact O-SG 3.43Å; K577-Y588 HydrophobicContact CB-CD1 4.18Å; K577-Y588 HydrophobicContact CB-CE1 3.56Å; K577-Y588 HydrophobicContact CG-CE1 4.24Å; K577-L609 HydrophobicContact CG-CD1 3.99Å
578V81.6Confident79.7Confident41 Ų4176.9 Ų76.925%0.24840%0.398CS..Hα-helixtrans-80.7-35.7-178.7172.90000112L574 L575 P580 C581 I582 Y588 L591L574-V578 WeakPolarHBondContact O-CB 3.48Å; L574-V578 WeakPolarHBondContact O-CG2 3.39Å; L574-V578 PolarHBondContact O-N 3.18Å; L575-V578 PolarHBondContact O-N 3.44Å; V578-P580 VanDerWaalsContact C-N 3.34Å; V578-C581 WeakPolarHBondContact O-CA 3.46Å; V578-C581 WeakPolarHBondContact O-CB 3.42Å; V578-C581 PolarHBondContact O-N 3.3Å; V578-I582 PolarHBondContact O-N 3.3Å; V578-Y588 HydrophobicContact CG2-CD1 3.93Å; V578-L591 HydrophobicContact CG2-CD2 3.89Å
579K77.7Confident79.2Confident163 Ų16375.5 Ų75.571%0.70940%0.403SS*.G310 helixtrans-47.7-44.5178.5-172.9177.5-178.9-179.10114.2L575 C581 I582L575-K579 WeakPolarHBondContact O-CB 3.29Å; L575-K579 PolarHBondContact O-N 2.87Å; K579-C581 VanDerWaalsContact C-N 3.33Å; K579-C581 PolarHBondContact O-N 3.22Å; K579-I582 WeakPolarHBondContact O-CD1 3.46Å
580P74.3Confident78.8Confident95 Ų9575.9 Ų75.962%0.61741%0.409SS*.G310 helixtrans-77.5-10.6175.229.2-35.8000115D576 K577 V578D576-P580 WeakPolarHBondContact O-CD 3.25Å; K577-P580 WeakPolarHBondContact O-CD 3.45Å; K577-P580 WeakPolarHBondContact O-CG 3.4Å; V578-P580 VanDerWaalsContact C-N 3.34Å
581C70Confident78.4Confident18 Ų1878.9 Ų78.912%0.12243%0.425CS..G310 helixtrans-100.9-4-171.4-61.50000114.8K577 V578 K579 P583 R584K577-C581 PolarHBondContact O-SG 3.43Å; V578-C581 WeakPolarHBondContact O-CA 3.46Å; V578-C581 WeakPolarHBondContact O-CB 3.42Å; V578-C581 PolarHBondContact O-N 3.3Å; K579-C581 VanDerWaalsContact C-N 3.33Å; K579-C581 PolarHBondContact O-N 3.22Å; C581-P583 VanDerWaalsContact C-CD 3.45Å; C581-P583 VanDerWaalsContact C-N 3.27Å; C581-R584 PolarHBondContact O-N 2.82Å; C581-R584 VanDerWaalsContact O-N 3.09Å
582I63.4Low78.1Confident135 Ų13581.7 Ų81.769%0.69244%0.436SS*.THydrogen-bonded Turntrans-47-35.7-172.8-62.3171.4000114.6V578 K579V578-I582 PolarHBondContact O-N 3.3Å; K579-I582 WeakPolarHBondContact O-CD1 3.46Å
583P59.4Low77.7Confident116 Ų11679.5 Ų79.575%0.75342%0.424SS*.THydrogen-bonded Turntrans-101.615.5-179.4-122.8000116.6C581C581-P583 VanDerWaalsContact C-CD 3.45Å; C581-P583 VanDerWaalsContact C-N 3.27Å
584R60.4Low77.4Confident154 Ų15478 Ų7858%0.58142%0.417SS*.SBendtrans-130138-171.7-60-173.7-176.8-131.4-1.1113.9C581 C586 I614C581-R584 PolarHBondContact O-N 2.82Å; C581-R584 VanDerWaalsContact O-N 3.09Å; R584-C586 PolarHBondContact O-N 3.48Å; R584-C586 PolarHBondContact O-SG 2.96Å; R584-I614 HydrophobicContact CB-CG2 4.31Å
585D68.9Low77.3Confident89 Ų8981.7 Ų81.748%0.47643%0.434SS..  trans-56.497.1164.4-63.7-22.7000108.7T615 T617D585-T615 WeakPolarHBondContact CB-OG1 3.25Å; D585-T615 PolarHBondContact O-N 3.38Å; D585-T615 PolarHBondContact O-OG1 2.94Å; D585-T617 PolarHBondContact OD2-OG1 3.19Å
586C78.7Confident77.3Confident13 Ų1385 Ų859%0.08844%0.438CS..BIsolated β-bridgetrans-137159.9179.767.90000110.9R584 Y588 A589 V612 I613 I614R584-C586 PolarHBondContact O-N 3.48Å; R584-C586 PolarHBondContact O-SG 2.96Å; C586-Y588 PolarHBondContact O-N 3.43Å; C586-Y588 VanDerWaalsContact O-N 3.16Å; C586-A589 VanDerWaalsContact O-CB 3.26Å; C586-A589 WeakPolarHBondContact O-CB 3.41Å; C586-A589 PolarHBondContact O-N 3.03Å; C586-V612 HydrophobicContact CB-CG1 4.32Å; C586-I613 WeakPolarHBondContact CA-O 3.38Å; C586-I613 VanDerWaalsContact CB-O 3.32Å; C586-I613 WeakPolarHBondContact CB-O 3.37Å; C586-I614 HydrophobicContact CB-CG1 4.41Å
587N80.8Confident77.3Confident51 Ų5182.3 Ų82.327%0.27343%0.431SS..G310 helixtrans-58.7-25.2177.463.7-35.3000113.8A589 D590 E611 I613N587-A589 PolarHBondContact O-N 3.21Å; N587-D590 PolarHBondContact O-N 3.31Å; N587-E611 PolarHBondContact ND2-O 3Å; N587-I613 HydrophobicContact CB-CB 4.46Å; N587-I613 PolarHBondContact N-O 3.29Å; N587-I613 VanDerWaalsContact N-O 3.08Å; N587-I613 PolarHBondContact OD1-N 3.42Å; N587-I613 PolarHBondContact OD1-O 2.62Å
588Y80.7Confident77.6Confident6 Ų678 Ų782%0.02441%0.414CS..G310 helixtrans-72.3-4.4175.9-84.2-105.1000114.4L574 K577 V578 C586 D590 V594 L609 P610 V612L574-Y588 HydrophobicContact CD2-CD1 4.5Å; L574-Y588 HydrophobicContact CD2-CE1 4.07Å; K577-Y588 HydrophobicContact CB-CD1 4.18Å; K577-Y588 HydrophobicContact CB-CE1 3.56Å; K577-Y588 HydrophobicContact CG-CE1 4.24Å; V578-Y588 HydrophobicContact CG2-CD1 3.93Å; C586-Y588 PolarHBondContact O-N 3.43Å; C586-Y588 VanDerWaalsContact O-N 3.16Å; Y588-D590 PolarHBondContact O-N 2.96Å; Y588-V594 HydrophobicContact CD1-CG1 4.15Å; Y588-V594 HydrophobicContact CD1-CG2 4.16Å; Y588-V594 HydrophobicContact CD2-CG2 4.31Å; Y588-V594 HydrophobicContact CE1-CG1 3.73Å; Y588-V594 HydrophobicContact CE1-CG2 4.42Å; Y588-V594 HydrophobicContact CG-CG2 4.13Å; Y588-L609 WeakPolarHBondContact OH-CB 3.24Å; Y588-P610 WeakPolarHBondContact CE2-O 3.49Å; Y588-P610 PolarHBondContact OH-O 3.17Å; Y588-V612 HydrophobicContact CD2-CB 4.21Å; Y588-V612 HydrophobicContact CD2-CG1 4.34Å; Y588-V612 HydrophobicContact CD2-CG2 3.7Å; Y588-V612 HydrophobicContact CE2-CB 4.16Å; Y588-V612 HydrophobicContact CE2-CG2 3.45Å; Y588-V612 VanDerWaalsContact CE2-CG2 3.45Å
589A77.2Confident78Confident84 Ų8480.4 Ų80.469%0.69443%0.429SS*.G310 helixtrans-62.1-33.5166.100000111.6C586 N587 L591C586-A589 VanDerWaalsContact O-CB 3.26Å; C586-A589 WeakPolarHBondContact O-CB 3.41Å; C586-A589 PolarHBondContact O-N 3.03Å; N587-A589 PolarHBondContact O-N 3.21Å; A589-L591 PolarHBondContact O-N 2.96Å
590D81.5Confident78.6Confident81 Ų8175.9 Ų75.943%0.43341%0.408SS..  trans-90.482.1170.9-179.813.6000110.7N587 Y588 E592 G593 V594N587-D590 PolarHBondContact O-N 3.31Å; Y588-D590 PolarHBondContact O-N 2.96Å; D590-E592 PolarHBondContact O-N 3.27Å; D590-E592 PolarHBondContact OD1-N 2.89Å; D590-G593 VanDerWaalsContact CG-N 3.29Å; D590-G593 PolarHBondContact O-N 3.4Å; D590-G593 PolarHBondContact OD1-N 3.18Å; D590-G593 WeakPolarHBondContact OD2-CA 3.23Å; D590-G593 PolarHBondContact OD2-N 3.27Å; D590-V594 WeakPolarHBondContact O-CG2 3.06Å; D590-V594 PolarHBondContact O-N 2.92Å; D590-V594 VanDerWaalsContact O-N 3.08Å
591L81.4Confident79.2Confident82 Ų8273.1 Ų73.143%0.42939%0.388SS..Hα-helixtrans-57.8-35.8177.4-74.6165.5000112.7V578 A589 V594 Q595V578-L591 HydrophobicContact CG2-CD2 3.89Å; A589-L591 PolarHBondContact O-N 2.96Å; L591-V594 PolarHBondContact O-N 3.34Å; L591-Q595 WeakPolarHBondContact O-CB 3.4Å; L591-Q595 VanDerWaalsContact O-CG 3.29Å; L591-Q595 WeakPolarHBondContact O-CG 3.31Å; L591-Q595 PolarHBondContact O-N 2.75Å
592E81.5Confident80Confident139 Ų13975.6 Ų75.665%0.6541%0.409SS*.Hα-helixtrans-70.8-39-179.4-66.3-175.1177.500111.6D590 Q595 R596D590-E592 PolarHBondContact O-N 3.27Å; D590-E592 PolarHBondContact OD1-N 2.89Å; E592-Q595 PolarHBondContact O-N 3.36Å; E592-R596 WeakPolarHBondContact O-CG 3.15Å; E592-R596 PolarHBondContact O-N 3.19Å; E592-R596 PolarHBondContact O-NE 2.88Å
593G82.2Confident81.2Confident19 Ų1976.7 Ų76.720%0.19642%0.416CS..Hα-helixtrans-60.8-45.6171.400000112.3D590 R596 A597D590-G593 VanDerWaalsContact CG-N 3.29Å; D590-G593 PolarHBondContact O-N 3.4Å; D590-G593 PolarHBondContact OD1-N 3.18Å; D590-G593 WeakPolarHBondContact OD2-CA 3.23Å; D590-G593 PolarHBondContact OD2-N 3.27Å; G593-R596 PolarHBondContact O-N 3.08Å; G593-A597 PolarHBondContact O-N 3.05Å; G593-A597 VanDerWaalsContact O-N 3.08Å
594V84.6Confident82.6Confident6 Ų674.8 Ų74.84%0.03641%0.405CS..Hα-helixtrans-64.2-42.4177.3178.80000111.4L574 Y588 D590 L591 R596 A597 A598 L609 P610L574-V594 HydrophobicContact CD2-CB 4.41Å; L574-V594 HydrophobicContact CD2-CG1 3.55Å; Y588-V594 HydrophobicContact CD1-CG1 4.15Å; Y588-V594 HydrophobicContact CD1-CG2 4.16Å; Y588-V594 HydrophobicContact CD2-CG2 4.31Å; Y588-V594 HydrophobicContact CE1-CG1 3.73Å; Y588-V594 HydrophobicContact CE1-CG2 4.42Å; Y588-V594 HydrophobicContact CG-CG2 4.13Å; D590-V594 WeakPolarHBondContact O-CG2 3.06Å; D590-V594 PolarHBondContact O-N 2.92Å; D590-V594 VanDerWaalsContact O-N 3.08Å; L591-V594 PolarHBondContact O-N 3.34Å; V594-R596 PolarHBondContact O-N 3.18Å; V594-A597 PolarHBondContact O-N 3.04Å; V594-A598 PolarHBondContact O-N 3.42Å; V594-L609 HydrophobicContact CG1-CD2 4.32Å; V594-P610 HydrophobicContact CG1-CG 4.25Å
595Q85.5Confident83.9Confident85 Ų8573.5 Ų73.540%0.39741%0.406SS..Hα-helixtrans-61.6-40.7176.1-77.8177.80.700112.5L570 L574 L591 E592 A597 A598L570-Q595 HydrophobicContact CD2-CG 4.49Å; L574-Q595 HydrophobicContact CD1-CG 3.75Å; L591-Q595 WeakPolarHBondContact O-CB 3.4Å; L591-Q595 VanDerWaalsContact O-CG 3.29Å; L591-Q595 WeakPolarHBondContact O-CG 3.31Å; L591-Q595 PolarHBondContact O-N 2.75Å; E592-Q595 PolarHBondContact O-N 3.36Å; Q595-A597 VanDerWaalsContact C-N 3.31Å; Q595-A597 PolarHBondContact O-N 3.27Å; Q595-A598 WeakPolarHBondContact O-CB 3.43Å; Q595-A598 PolarHBondContact O-N 2.73Å
596R84Confident84.9Confident194 Ų19472.1 Ų72.173%0.73240%0.398SS*.Hα-helixtrans-66.6-32.2176.2-78.1-177-70.8148.6-4.2113.1E592 G593 V594E592-R596 WeakPolarHBondContact O-CG 3.15Å; E592-R596 PolarHBondContact O-N 3.19Å; E592-R596 PolarHBondContact O-NE 2.88Å; G593-R596 PolarHBondContact O-N 3.08Å; V594-R596 PolarHBondContact O-N 3.18Å
597A86.4Confident85.6Confident55 Ų5573.7 Ų73.746%0.45540%0.402SS..Hα-helixtrans-85.5-10.7178.200000113.6G593 V594 Q595 P610G593-A597 PolarHBondContact O-N 3.05Å; G593-A597 VanDerWaalsContact O-N 3.08Å; V594-A597 PolarHBondContact O-N 3.04Å; Q595-A597 VanDerWaalsContact C-N 3.31Å; Q595-A597 PolarHBondContact O-N 3.27Å; A597-P610 HydrophobicContact CB-CG 3.56Å
598A88.8Confident86Confident12 Ų1275.4 Ų75.410%0.09941%0.412CS..  trans-71.3129.5178.900000111.1L570 V594 Q595 W607 L609L570-A598 HydrophobicContact CD1-CB 3.76Å; V594-A598 PolarHBondContact O-N 3.42Å; Q595-A598 WeakPolarHBondContact O-CB 3.43Å; Q595-A598 PolarHBondContact O-N 2.73Å; A598-W607 HydrophobicContact CB-CE3 3.84Å; A598-W607 HydrophobicContact CB-CZ3 4.35Å; A598-L609 HydrophobicContact CB-CD2 3.86Å
599V90.8Very high86.5Confident91 Ų9176.7 Ų76.755%0.55242%0.419SS*.EExtended strand (participates in β ladder)trans-115.9130.4178.7-178.60000109.5D601 N608V599-D601 PolarHBondContact O-N 3.11Å; V599-N608 PolarHBondContact N-O 3.19Å; V599-N608 PolarHBondContact O-N 3.02Å
600W89.1Confident86.9Confident69 Ų6974.4 Ų74.426%0.26140%0.397SS..EExtended strand (participates in β ladder)trans-76122174.9175.5-102.2000110.7Q566 K569 Q605 W607Q566-W600 HydrophobicContact CB-CE3 4.33Å; Q566-W600 HydrophobicContact CB-CH2 4.49Å; Q566-W600 HydrophobicContact CB-CZ3 4.25Å; Q566-W600 HydrophobicContact CG-CD2 3.98Å; Q566-W600 HydrophobicContact CG-CE3 4Å; Q566-W600 HydrophobicContact CG-CH2 3.66Å; Q566-W600 HydrophobicContact CG-CZ2 3.67Å; Q566-W600 HydrophobicContact CG-CZ3 3.84Å; K569-W600 HydrophobicContact CD-CH2 4.44Å; K569-W600 HydrophobicContact CD-CZ3 4.29Å; W600-Q605 HydrophobicContact CH2-CB 4.08Å; W600-Q605 WeakPolarHBondContact CH2-O 3.15Å; W600-Q605 HydrophobicContact CZ2-CB 4.09Å; W600-Q605 WeakPolarHBondContact CZ3-O 3.43Å; W600-W607 HydrophobicContact CB-CD2 4.29Å; W600-W607 HydrophobicContact CB-CE3 4.08Å; W600-W607 HydrophobicContact CB-CH2 4.11Å; W600-W607 HydrophobicContact CB-CZ2 4.3Å; W600-W607 HydrophobicContact CB-CZ3 3.99Å; W600-W607 AromaticContact CE3-CD1 3.6Å; W600-W607 AromaticContact CE3-CD2 3.94Å; W600-W607 HydrophobicContact CE3-CD2 3.94Å; W600-W607 AromaticContact CE3-CE2 3.62Å; W600-W607 AromaticContact CE3-CG 3.94Å; W600-W607 HydrophobicContact CE3-CG 3.94Å; W600-W607 HydrophobicContact CE3-CZ2 4.28Å; W600-W607 AromaticContact CE3-NE1 3.34Å; W600-W607 VanDerWaalsContact CE3-NE1 3.34Å; W600-W607 AromaticContact CZ3-CD1 3.74Å; W600-W607 HydrophobicContact CZ3-CG 4.45Å; W600-W607 AromaticContact CZ3-NE1 3.6Å
601D88.8Confident86.9Confident37 Ų3778.7 Ų78.720%0.19841%0.414CS..EExtended strand (participates in β ladder)trans-91.8111.3169.9-174.5-17.4000109.3V599 D603 C604 Q605 N606V599-D601 PolarHBondContact O-N 3.11Å; D601-D603 VanDerWaalsContact C-N 3.33Å; D601-D603 WeakPolarHBondContact OD1-CB 3.16Å; D601-D603 PolarHBondContact OD1-N 3.47Å; D601-C604 HydrophobicContact CB-CB 4.21Å; D601-C604 PolarHBondContact OD1-N 2.67Å; D601-C604 VanDerWaalsContact OD1-N 3.12Å; D601-C604 WeakPolarHBondContact OD2-CB 3.3Å; D601-C604 PolarHBondContact OD2-SG 2.85Å; D601-Q605 VanDerWaalsContact O-CA 3.24Å; D601-Q605 WeakPolarHBondContact O-CA 3.45Å; D601-Q605 PolarHBondContact O-N 3.16Å; D601-N606 WeakPolarHBondContact CB-O 3.47Å; D601-N606 PolarHBondContact N-O 2.9Å; D601-N606 PolarHBondContact O-N 2.76Å
602A86.9Confident86.9Confident70 Ų7077.4 Ų77.458%0.57941%0.41SS*.THydrogen-bonded Turntrans-69.8-30179.700000113
603D87.9Confident86.7Confident157 Ų15776 Ų7684%0.8441%0.405SS*.THydrogen-bonded Turntrans-77.3-44.1-177.2-64.2-33000110.3D601 Q605D601-D603 VanDerWaalsContact C-N 3.33Å; D601-D603 WeakPolarHBondContact OD1-CB 3.16Å; D601-D603 PolarHBondContact OD1-N 3.47Å; D603-Q605 VanDerWaalsContact C-N 3.33Å
604C88.5Confident86.3Confident76 Ų7678.9 Ų78.951%0.51442%0.416SS..THydrogen-bonded Turntrans-83.9-8.2176.8-62.80000113.7D601 N606D601-C604 HydrophobicContact CB-CB 4.21Å; D601-C604 PolarHBondContact OD1-N 2.67Å; D601-C604 VanDerWaalsContact OD1-N 3.12Å; D601-C604 WeakPolarHBondContact OD2-CB 3.3Å; D601-C604 PolarHBondContact OD2-SG 2.85Å; C604-N606 HydrophobicContact CB-CB 4.27Å; C604-N606 PolarHBondContact O-N 2.84Å
605Q87.9Confident85.6Confident128 Ų12882.6 Ų82.660%0.59844%0.438SS*.THydrogen-bonded Turntrans4934.9-169.3-59.3-171.9-13.300113.2K569 W600 D601 D603K569-Q605 WeakPolarHBondContact CD-O 3.48Å; K569-Q605 VanDerWaalsContact CE-O 3.27Å; K569-Q605 WeakPolarHBondContact CE-O 3.16Å; K569-Q605 PolarHBondContact NZ-O 2.82Å; W600-Q605 HydrophobicContact CH2-CB 4.08Å; W600-Q605 WeakPolarHBondContact CH2-O 3.15Å; W600-Q605 HydrophobicContact CZ2-CB 4.09Å; W600-Q605 WeakPolarHBondContact CZ3-O 3.43Å; D601-Q605 VanDerWaalsContact O-CA 3.24Å; D601-Q605 WeakPolarHBondContact O-CA 3.45Å; D601-Q605 PolarHBondContact O-N 3.16Å; D603-Q605 VanDerWaalsContact C-N 3.33Å
606N90.6Very high84.7Confident60 Ų6087.2 Ų87.232%0.32146%0.457SS..EExtended strand (participates in β ladder)trans-129.5154.5-174.9-83.9-13.7000110.4K569 D601 C604K569-N606 WeakPolarHBondContact CE-OD1 3.41Å; K569-N606 PolarHBondContact NZ-OD1 3.04Å; D601-N606 WeakPolarHBondContact CB-O 3.47Å; D601-N606 PolarHBondContact N-O 2.9Å; D601-N606 PolarHBondContact O-N 2.76Å; C604-N606 HydrophobicContact CB-CB 4.27Å; C604-N606 PolarHBondContact O-N 2.84Å
607W92Very high83.5Confident45 Ų4583.1 Ų83.117%0.1745%0.454CS..EExtended strand (participates in β ladder)trans-82.5130.4165.4-63.584000110.6Q566 L570 Q573 A598 W600 L609Q566-W607 HydrophobicContact CB-CZ2 4.14Å; Q566-W607 PolarHBondContact O-NE1 2.6Å; L570-W607 HydrophobicContact CB-CD2 4.06Å; L570-W607 HydrophobicContact CB-CG 3.98Å; L570-W607 HydrophobicContact CB-CZ2 4.38Å; L570-W607 HydrophobicContact CD1-CB 3.88Å; L570-W607 HydrophobicContact CD1-CD2 3.76Å; L570-W607 HydrophobicContact CD1-CE3 4.08Å; L570-W607 HydrophobicContact CD1-CG 3.66Å; L570-W607 HydrophobicContact CD2-CD2 4.4Å; L570-W607 HydrophobicContact CD2-CH2 4.48Å; L570-W607 HydrophobicContact CD2-CZ2 4.36Å; L570-W607 HydrophobicContact CG-CD2 4.29Å; L570-W607 HydrophobicContact CG-CG 4.37Å; Q573-W607 PolarHBondContact NE2-O 3.3Å; A598-W607 HydrophobicContact CB-CE3 3.84Å; A598-W607 HydrophobicContact CB-CZ3 4.35Å; W600-W607 HydrophobicContact CB-CD2 4.29Å; W600-W607 HydrophobicContact CB-CE3 4.08Å; W600-W607 HydrophobicContact CB-CH2 4.11Å; W600-W607 HydrophobicContact CB-CZ2 4.3Å; W600-W607 HydrophobicContact CB-CZ3 3.99Å; W600-W607 AromaticContact CE3-CD1 3.6Å; W600-W607 AromaticContact CE3-CD2 3.94Å; W600-W607 HydrophobicContact CE3-CD2 3.94Å; W600-W607 AromaticContact CE3-CE2 3.62Å; W600-W607 AromaticContact CE3-CG 3.94Å; W600-W607 HydrophobicContact CE3-CG 3.94Å; W600-W607 HydrophobicContact CE3-CZ2 4.28Å; W600-W607 AromaticContact CE3-NE1 3.34Å; W600-W607 VanDerWaalsContact CE3-NE1 3.34Å; W600-W607 AromaticContact CZ3-CD1 3.74Å; W600-W607 HydrophobicContact CZ3-CG 4.45Å; W600-W607 AromaticContact CZ3-NE1 3.6Å; W607-L609 PolarHBondContact O-N 3.47Å
608N90.4Very high82.4Confident88 Ų8889.7 Ų89.747%0.47147%0.472SS..EExtended strand (participates in β ladder)trans-80.999.1167.2-67.9-21.4000107.7V599V599-N608 PolarHBondContact N-O 3.19Å; V599-N608 PolarHBondContact O-N 3.02Å
609L89.4Confident80.9Confident33 Ų3396.7 Ų96.717%0.17351%0.507CS..PPolyproline II helixtrans-85.8145.3177-67.1177.3000110.9L570 Q573 L574 K577 Y588 V594 A598 W607L570-L609 HydrophobicContact CD1-CD2 3.66Å; Q573-L609 HydrophobicContact CB-CD1 3.67Å; L574-L609 HydrophobicContact CD2-CD1 4.25Å; L574-L609 HydrophobicContact CD2-CD2 3.88Å; L574-L609 HydrophobicContact CG-CD2 4.32Å; K577-L609 HydrophobicContact CG-CD1 3.99Å; Y588-L609 WeakPolarHBondContact OH-CB 3.24Å; V594-L609 HydrophobicContact CG1-CD2 4.32Å; A598-L609 HydrophobicContact CB-CD2 3.86Å; W607-L609 PolarHBondContact O-N 3.47Å
610P86Confident79.4Confident35 Ų3598 Ų9823%0.22752%0.517CS..PPolyproline II helixtrans-53.1146.1169-2431.4000112.4Y588 V594 A597Y588-P610 WeakPolarHBondContact CE2-O 3.49Å; Y588-P610 PolarHBondContact OH-O 3.17Å; V594-P610 HydrophobicContact CG1-CG 4.25Å; A597-P610 HydrophobicContact CB-CG 3.56Å
611E83Confident78Confident172 Ų172104.1 Ų104.180%0.80455%0.546SS*.PPolyproline II helixtrans-66151.2174.6-65.7-172.8169.100111.9N587 I613N587-E611 PolarHBondContact ND2-O 3Å; E611-I613 PolarHBondContact O-N 2.84Å
612V79.9Confident76Confident55 Ų55108.7 Ų108.733%0.33358%0.575SS.*  trans-77115.3178-1790000109C586 Y588 I614C586-V612 HydrophobicContact CB-CG1 4.32Å; Y588-V612 HydrophobicContact CD2-CB 4.21Å; Y588-V612 HydrophobicContact CD2-CG1 4.34Å; Y588-V612 HydrophobicContact CD2-CG2 3.7Å; Y588-V612 HydrophobicContact CE2-CB 4.16Å; Y588-V612 HydrophobicContact CE2-CG2 3.45Å; Y588-V612 VanDerWaalsContact CE2-CG2 3.45Å; V612-I614 HydrophobicContact CG1-CG1 4.33Å
613I78.3Confident74.1Confident109 Ų109109.2 Ų109.256%0.55958%0.58SS**  trans-104.8117.8175-55.8172.8000107.8C586 N587 E611C586-I613 WeakPolarHBondContact CA-O 3.38Å; C586-I613 VanDerWaalsContact CB-O 3.32Å; C586-I613 WeakPolarHBondContact CB-O 3.37Å; N587-I613 HydrophobicContact CB-CB 4.46Å; N587-I613 PolarHBondContact N-O 3.29Å; N587-I613 VanDerWaalsContact N-O 3.08Å; N587-I613 PolarHBondContact OD1-N 3.42Å; N587-I613 PolarHBondContact OD1-O 2.62Å; E611-I613 PolarHBondContact O-N 2.84Å
614I74.2Confident72.2Confident80 Ų80106.4 Ų106.441%0.4157%0.572SS.*BIsolated β-bridgetrans-94.9111.8175.6-58.5169.5000108.6R584 C586 V612 K616R584-I614 HydrophobicContact CB-CG2 4.31Å; C586-I614 HydrophobicContact CB-CG1 4.41Å; V612-I614 HydrophobicContact CG1-CG1 4.33Å; I614-K616 PolarHBondContact O-N 2.89Å
615T69.5Low69.7Low84 Ų84107.4 Ų107.452%0.51558%0.579SS.*  trans-78.110317143.40000108.7D585 T617D585-T615 WeakPolarHBondContact CB-OG1 3.25Å; D585-T615 PolarHBondContact O-N 3.38Å; D585-T615 PolarHBondContact O-OG1 2.94Å; T615-T617 PolarHBondContact O-N 2.87Å
616K65.3Low67.5Low182 Ų182107.1 Ų107.179%0.79158%0.581SS**  trans-71.797.5169.2-68.4-177.4-179.1177.80108.6I614 K618I614-K616 PolarHBondContact O-N 2.89Å; K616-K618 VanDerWaalsContact C-N 3.35Å; K616-K618 PolarHBondContact O-N 2.86Å
617T59.5Low65.3Low108 Ų108110 Ų11066%0.66360%0.596SS**  trans-61.898.2162.426.50000107.8D585 T615 L619D585-T617 PolarHBondContact OD2-OG1 3.19Å; T615-T617 PolarHBondContact O-N 2.87Å; T617-L619 PolarHBondContact O-N 3.26Å
618K62.7Low62.9Low193 Ų193112.9 Ų112.984%0.83962%0.622SS**  trans-67.9112.6165.6-72.5-178.7-179.6174.70105.7K616K616-K618 VanDerWaalsContact C-N 3.35Å; K616-K618 PolarHBondContact O-N 2.86Å
619L58.8Low60.7Low159 Ų159112 Ų11283%0.83263%0.627SS**PPolyproline II helixtrans-46132.7161.8-86.4148.1000107.4T617 K621T617-L619 PolarHBondContact O-N 3.26Å; L619-K621 PolarHBondContact O-N 2.91Å
620P58.7Low58.3Low117 Ų117115.1 Ų115.176%0.7664%0.643SS**PPolyproline II helixtrans-52.9126.1174.320.6-29.2000106.7T622P620-T622 PolarHBondContact O-N 3.03Å; P620-T622 VanDerWaalsContact O-N 3.1Å
621K58.8Low56.1Low199 Ų199116.3 Ų116.387%0.86566%0.656SS**PPolyproline II helixtrans-50.2126.9169.1-67.3-178.7178.2-177.20104.9L619 A623L619-K621 PolarHBondContact O-N 2.91Å; K621-A623 PolarHBondContact O-N 2.92Å
622T46.7Very low54.1Low133 Ų133115.1 Ų115.182%0.81666%0.655SS**  trans-41.2119166.8-47.20000104.9P620 S624P620-T622 PolarHBondContact O-N 3.03Å; P620-T622 VanDerWaalsContact O-N 3.1Å; T622-S624 PolarHBondContact O-N 2.95Å
623A48.6Very low52.4Low81 Ų81121.2 Ų121.267%0.66968%0.677SS**  trans-52.9109.1172.100000103.2K621 C625K621-A623 PolarHBondContact O-N 2.92Å; A623-C625 PolarHBondContact O-N 3.39Å
624S46.3Very low50.4Low98 Ų98121.2 Ų121.269%0.68568%0.677SS**  trans-60.492.9158.650.60000101.2T622 N626T622-S624 PolarHBondContact O-N 2.95Å; S624-N626 PolarHBondContact O-N 3.06Å
625C37.1Very low48.6Very low97 Ų97124.8 Ų124.866%0.65570%0.697SS**  trans-42.6120154.2-750000102.8A623 L627A623-C625 PolarHBondContact O-N 3.39Å; C625-L627 HydrophobicContact CB-CD1 4.3Å; C625-L627 HydrophobicContact CB-CG 4.48Å; C625-L627 PolarHBondContact O-N 2.86Å
626N41.7Very low47.2Very low121 Ų121127.7 Ų127.765%0.64771%0.71SS**  trans-65.667.6173.7-78.3-21.3000107.4S624 C628 A629S624-N626 PolarHBondContact O-N 3.06Å; N626-C628 PolarHBondContact O-N 2.77Å; N626-A629 HydrophobicContact CB-CB 3.9Å; N626-A629 PolarHBondContact O-N 3.21Å
627L44.2Very low46.1Very low120 Ų120127 Ų12763%0.62872%0.715SS**Hα-helixtrans-67-18.1165.8-90152.9000109.5C625 L630 A631C625-L627 HydrophobicContact CB-CD1 4.3Å; C625-L627 HydrophobicContact CB-CG 4.48Å; C625-L627 PolarHBondContact O-N 2.86Å; L627-L630 PolarHBondContact O-N 3.43Å; L627-A631 WeakPolarHBondContact O-CB 3.35Å; L627-A631 PolarHBondContact O-N 3.36Å
628C42.2Very low45.5Very low106 Ų106130.1 Ų130.172%0.71672%0.722SS**Hα-helixtrans-72.2-23.2166.5-76.50000114N626 L630N626-C628 PolarHBondContact O-N 2.77Å; C628-L630 VanDerWaalsContact C-N 3.3Å
629A42.8Very low44.4Very low69 Ų69128.3 Ų128.357%0.5771%0.714SS**Hα-helixtrans-79-18.9170.800000112.1N626N626-A629 HydrophobicContact CB-CB 3.9Å; N626-A629 PolarHBondContact O-N 3.21Å
630L39.3Very low43.7Very low100 Ų100126.5 Ų126.552%0.52471%0.71SS.*Hα-helixtrans-88.8-27.8173.2-139.191.3000112.5L627 C628 D632 F633 I634L627-L630 PolarHBondContact O-N 3.43Å; C628-L630 VanDerWaalsContact C-N 3.3Å; L630-D632 VanDerWaalsContact C-N 3.28Å; L630-D632 PolarHBondContact O-N 2.82Å; L630-F633 PolarHBondContact O-N 3.38Å; L630-I634 HydrophobicContact CD2-CD1 4.07Å; L630-I634 PolarHBondContact O-N 3.24Å
631A40.7Very low42.8Very low59 Ų59129.4 Ų129.449%0.48871%0.711SS.*Hα-helixtrans-66.6-27.7179.100000113L627 F633L627-A631 WeakPolarHBondContact O-CB 3.35Å; L627-A631 PolarHBondContact O-N 3.36Å; A631-F633 PolarHBondContact O-N 2.81Å
632D40.9Very low42.1Very low148 Ų148124.5 Ų124.579%0.79169%0.693SS**THydrogen-bonded Turntrans-71.5-11.6171.8-73.6-17.3000113L630L630-D632 VanDerWaalsContact C-N 3.28Å; L630-D632 PolarHBondContact O-N 2.82Å
633F43.5Very low41.9Very low182 Ų182120.8 Ų120.880%0.79868%0.676SS**THydrogen-bonded Turntrans-110-4.7-176-130.3-90.6000115.1L630 A631L630-F633 PolarHBondContact O-N 3.38Å; A631-F633 PolarHBondContact O-N 2.81Å
634I36.8Very low41.4Very low109 Ų109122.6 Ų122.656%0.55967%0.674SS**  trans-135.469.3-177.3-47.8179.6000109.8L630 D636L630-I634 HydrophobicContact CD2-CD1 4.07Å; L630-I634 PolarHBondContact O-N 3.24Å; I634-D636 PolarHBondContact O-N 2.87Å
635N37Very low41.2Very low155 Ų155121.9 Ų121.983%0.82967%0.669SS**  trans-8178.4147.5-86-33.1000107.3
636D38.8Very low41.2Very low146 Ų146123.1 Ų123.178%0.78167%0.669SS**  trans-135.7117.5157.2-87.5-39.8000108.8I634 E638I634-D636 PolarHBondContact O-N 2.87Å; D636-E638 PolarHBondContact O-N 3.43Å
637N44Very low40.9Very low167 Ų167126.8 Ų126.889%0.89367%0.674SS**SBendtrans-62.888-174.6-75.1-46.4000111.3
638E46.7Very low40.7Very low174 Ų174125.3 Ų125.381%0.81367%0.673SS**  trans-158.39.1158.3-119.8172.8-160.700119D636D636-E638 PolarHBondContact O-N 3.43Å
639F38.7Very low40.4Very low155 Ų155123.8 Ų123.868%0.6867%0.668SS**  trans-124.323.8-178.6-99.3-76.9000117.3F641 I642F639-F641 PolarHBondContact O-N 2.72Å; F639-I642 HydrophobicContact CD1-CB 4.49Å; F639-I642 HydrophobicContact CD1-CD1 3.49Å; F639-I642 VanDerWaalsContact CD1-CD1 3.49Å; F639-I642 HydrophobicContact CD1-CG1 3.79Å; F639-I642 HydrophobicContact CE1-CD1 3.38Å; F639-I642 HydrophobicContact CE1-CG1 3.98Å; F639-I642 PolarHBondContact O-N 2.79Å
640T43.5Very low39.9Very low121 Ų121125.3 Ų125.374%0.74268%0.675SS**Hα-helixtrans-60.6-8.1171.936.10000114.7
641F40.6Very low39.4Very low178 Ų178125.8 Ų125.878%0.78169%0.687SS**Hα-helixtrans-77.9-34.9177.9-161.6-100.4000113.8F639F639-F641 PolarHBondContact O-N 2.72Å
642I43.4Very low38.9Very low95 Ų95127.3 Ų127.349%0.48769%0.693SS.*Hα-helixtrans-77.1-35.1-175-65.9-176.7000112.1F639 N644 S645 L646F639-I642 HydrophobicContact CD1-CB 4.49Å; F639-I642 HydrophobicContact CD1-CD1 3.49Å; F639-I642 VanDerWaalsContact CD1-CD1 3.49Å; F639-I642 HydrophobicContact CD1-CG1 3.79Å; F639-I642 HydrophobicContact CE1-CD1 3.38Å; F639-I642 HydrophobicContact CE1-CG1 3.98Å; F639-I642 PolarHBondContact O-N 2.79Å; I642-N644 VanDerWaalsContact C-N 3.28Å; I642-N644 PolarHBondContact O-N 2.83Å; I642-S645 PolarHBondContact O-N 3.19Å; I642-L646 HydrophobicContact CG2-CD1 4.42Å
643A43.3Very low38.3Very low55 Ų55131.4 Ų131.446%0.45570%0.698SS.*Hα-helixtrans-66-29.1-176.700000113.3
644N38.3Very low37.5Very low119 Ų119132 Ų13264%0.63670%0.703SS**Hα-helixtrans-78.2-28.8179.7-79.1-15000113I642I642-N644 VanDerWaalsContact C-N 3.28Å; I642-N644 PolarHBondContact O-N 2.83Å
645S41.8Very low37Very low83 Ų83134 Ų13458%0.5872%0.715SS**Hα-helixtrans-72.1-28.1177.1-118.30000113.3I642 S648I642-S645 PolarHBondContact O-N 3.19Å; S645-S648 PolarHBondContact O-OG 3.4Å; S645-S648 VanDerWaalsContact O-OG 3.12Å
646L38Very low36.5Very low124 Ų124134.1 Ų134.165%0.64971%0.711SS**Hα-helixtrans-80.7-27.9178.5-76.7164.4000112.7I642 S648 A649I642-L646 HydrophobicContact CG2-CD1 4.42Å; L646-S648 VanDerWaalsContact C-N 3.34Å; L646-A649 PolarHBondContact O-N 3.42Å
647R35.5Very low35.9Very low198 Ų198135.9 Ų135.975%0.74772%0.716SS**Hα-helixtrans-76.1-22.3-178.4-150.8177.6-71.1-112.63.6112.9
648S38.6Very low34.9Very low88 Ų88135.2 Ų135.262%0.61571%0.706SS**THydrogen-bonded Turntrans-82.2-12.1174.553.40000114.4S645 L646S645-S648 PolarHBondContact O-OG 3.4Å; S645-S648 VanDerWaalsContact O-OG 3.12Å; L646-S648 VanDerWaalsContact C-N 3.34Å
649A35.8Very low34Very low74 Ų74134.6 Ų134.661%0.61271%0.707SS**SBendtrans-94-10.4-174.500000114.6L646L646-A649 PolarHBondContact O-N 3.42Å
650S32.3Very low33.3Very low101 Ų101134.6 Ų134.671%0.70671%0.714SS**SBendtrans-110.610.3-17367.10000115.3
651S29.3Very low32.3Very low111 Ų111131.6 Ų131.678%0.77671%0.707SS**SBendtrans-91.213.5177.476.50000114.6
652S29.9Very low31.4Very low90 Ų90132.2 Ų132.263%0.62971%0.713SS**  trans-127.993.5177.6630000110.8
653R27.7Very low30.5Very low234 Ų234138.9 Ų138.988%0.88373%0.733SS**  trans161.866.8151.5-88.8165.9-173.7-1603.2109.8
654Q26.8Very low29.4Very low195 Ų195141 Ų14191%0.91175%0.745SS**  trans-116.475.6150.6-94.9176.4-17.300105.6Q656Q654-Q656 PolarHBondContact O-N 3.17Å
655D28Very low28.6Very low151 Ų151139.8 Ų139.881%0.80775%0.746SS**  trans-75.1107.4167.7-79.6-32.7000107.8M657D655-M657 PolarHBondContact O-N 2.88Å
656Q25.1Very low27.7Very low158 Ų158143.1 Ų143.174%0.73876%0.757SS**  trans-58.6110.2162.1-68173.5-19.100108.6Q654 F658Q654-Q656 PolarHBondContact O-N 3.17Å; Q656-F658 HydrophobicContact CB-CD2 3.95Å; Q656-F658 HydrophobicContact CB-CE2 4.22Å; Q656-F658 HydrophobicContact CG-CE2 4.33Å
657M26.1Very low27.1Very low183 Ų183142.6 Ų142.690%0.90176%0.764SS**  trans-9685.9155.9-86.3-171.2160.600108.4D655D655-M657 PolarHBondContact O-N 2.88Å
658F22.5Very low26.7Very low153 Ų153140 Ų14067%0.67177%0.765SS**  trans-63.6121.1154.4-84.7-90.3000108.6Q656Q656-F658 HydrophobicContact CB-CD2 3.95Å; Q656-F658 HydrophobicContact CB-CE2 4.22Å; Q656-F658 HydrophobicContact CG-CE2 4.33Å
659L29.2Very low26.4Very low160 Ų160141.6 Ų141.684%0.83878%0.776SS**  trans-134.675.9156.7-84.9169.6000108.3G661L659-G661 PolarHBondContact O-N 2.76Å
660N23Very low26Very low155 Ų155140.9 Ų140.983%0.82978%0.775SS**  trans-74.299.4146.1-75.4-12.6000105.8
661G23.7Very low25.9Very low58 Ų58142.3 Ų142.360%0.59878%0.775SS**  trans-112.195.5171.800000108.8L659 Y663L659-G661 PolarHBondContact O-N 2.76Å; G661-Y663 PolarHBondContact O-N 3.4Å
662E21.1Very low25.9Very low192 Ų192144.1 Ų144.190%0.89777%0.771SS**  trans-56113.4161.5-68.5175.6150.700108.5
663Y24.1Very low26.1Very low235 Ų235146.7 Ų146.792%0.92278%0.777SS**  trans-106.294.5158.6-99.5-84.8000107.9G661G661-Y663 PolarHBondContact O-N 3.4Å
664S19.7Very low26.2Very low99 Ų99142.3 Ų142.369%0.69277%0.77SS**  trans-78.7155.2160.5-178.50000109.9
665S22Very low26.4Very low94 Ų94143.5 Ų143.566%0.65777%0.766SS**  trans73.7118.216358.60000120.3
666D22.5Very low26.5Very low153 Ų153144.3 Ų144.382%0.81877%0.765SS**  trans80.195.7133.9-57.7-13.9000119.7
667S26.4Very low26.7Very low113 Ų113142.7 Ų142.779%0.7977%0.766SS**  175130.4110.557.90000112.3
668D26.1Very low26.6Very low144 Ų144144.5 Ų144.577%0.7776%0.763SS**  trans66.199.7147.3-70.5-13.4000121.8G670D668-G670 PolarHBondContact O-N 3.44Å; D668-G670 VanDerWaalsContact O-N 3.16Å
669S32.7Very low26.8Very low120 Ų120142.1 Ų142.184%0.83976%0.762SS**  20.183.7118.3600000116.8
670G28.7Very low26.7Very low59 Ų59144.3 Ų144.361%0.60877%0.766SS**  trans-143.5-23.9167.600000114.8D668D668-G670 PolarHBondContact O-N 3.44Å; D668-G670 VanDerWaalsContact O-N 3.16Å
671D29.4Very low26.7Very low132 Ų132146.3 Ų146.371%0.70677%0.767SS**G310 helixtrans-103.29.8-164.9-82.8-20.2000116.3I673D671-I673 VanDerWaalsContact C-N 3.31Å; D671-I673 PolarHBondContact O-N 2.74Å
672E30.1Very low26.7Very low148 Ų148149.4 Ų149.469%0.69278%0.779SS**G310 helixtrans-81.1-5.9177.9-161.154.8-143.800113.7
673I32.5Very low26.8Very low145 Ų145145.2 Ų145.274%0.74477%0.77SS**G310 helixtrans-90.5-19178.6-61-178.2000112.5D671D671-I673 VanDerWaalsContact C-N 3.31Å; D671-I673 PolarHBondContact O-N 2.74Å
674L30Very low26.9Very low142 Ų142139.4 Ų139.474%0.74376%0.759SS**SBendtrans-97.3-0.4-174.3-72.3172.9000115.2
675R30.6Very low27.1Very low220 Ų220143.5 Ų143.583%0.8377%0.765SS**SBendtrans-101.1-3.6175.2-86.9-172.5165-163.7-2.1116
676Q29.9Very low27.2Very low167 Ų167147 Ų14778%0.7878%0.776SS**THydrogen-bonded Turntrans-89.97175.7-75.9-160.6-0.900115.6
677V29.8Very low27.3Very low124 Ų124143.3 Ų143.375%0.75277%0.773SS**THydrogen-bonded Turntrans-122.120.1-176.4-1610000113.9
678W25.1Very low27.1Very low221 Ų221150.2 Ų150.284%0.83778%0.782SS**  trans-138.765.3178.9-150.7-82.4000115.5
679P26.2Very low27.2Very low103 Ų103152.6 Ų152.667%0.66979%0.785SS**  trans-149.296.9130.633.8-14.3000112.8
680F26.3Very low26.8Very low207 Ų207153.9 Ų153.991%0.90879%0.788SS**  trans-152.570.3152.5-98.5-75.5000109
681F22.8Very low26.7Very low196 Ų196158.7 Ų158.786%0.8680%0.799SS**  trans-128.269.9166.7-129.3-84.9000108.7
682C23.9Very low26.5Very low124 Ų124156.8 Ų156.884%0.83880%0.795SS**  trans-159.5119.8159.5-113.10000111.3
683S23.6Very low26.3Very low103 Ų103155.7 Ų155.772%0.7280%0.801SS**  trans94.8117.5147.6-148.60000120.3
684T25.9Very low26.1Very low113 Ų113157.1 Ų157.169%0.69380%0.802SS**  trans84.2109134.933.50000122.2
685K24.3Very low26Very low185 Ų185158.4 Ų158.480%0.80481%0.808SS**  63.7124.4120.7-78.4-176.4177.31780120.4
686L24.3Very low26.4Very low169 Ų169156.8 Ų156.889%0.88581%0.807SS**  trans56105143.6-88.386.3000118.1
687G25.4Very low26.6Very low74 Ų74153.7 Ų153.776%0.76381%0.81SS**  trans-164.988.5156.800000111K689G687-K689 PolarHBondContact O-N 3.25Å
688R21.7Very low27Very low258 Ų258155 Ų15597%0.97481%0.806SS**  trans-56.5106.5164.3-86.9178.9170.9176.8-3108.1
689K27.6Very low28.1Very low194 Ų194147.4 Ų147.484%0.84379%0.786SS**  trans-129.7126.2158.5-87.8-173.6177.4177.70109.1G687 L691G687-K689 PolarHBondContact O-N 3.25Å; K689-L691 PolarHBondContact O-N 2.88Å
690V25.4Very low29Very low147 Ų147150.3 Ų150.389%0.89179%0.791SS**  trans-41.4112.5179.3177.80000110.6S692V690-S692 PolarHBondContact O-N 3.1Å
691L25.4Very low30Very low161 Ų161142.7 Ų142.784%0.84377%0.766SS**  trans-75.6101.9173.7-74.5162.9000108.1K689K689-L691 PolarHBondContact O-N 2.88Å
692S25Very low31.3Very low91 Ų91136.1 Ų136.164%0.63674%0.738SS**  trans-63.1141.6153.850.30000108.3V690 K694V690-S692 PolarHBondContact O-N 3.1Å; S692-K694 PolarHBondContact O-N 3.21Å
693P27.5Very low32.6Very low125 Ų125135.2 Ų135.281%0.81273%0.725SS**  trans-70.3106.5-172.78.61.6000108.7I695P693-I695 PolarHBondContact O-N 3.43Å
694K26.6Very low33.6Very low175 Ų175135.5 Ų135.576%0.76172%0.717SS**  trans-61.4108.9163.7-75-178.3177.1179.20106.5S692 F696S692-K694 PolarHBondContact O-N 3.21Å; K694-F696 WeakPolarHBondContact O-CD2 3.44Å; K694-F696 PolarHBondContact O-N 3.49Å
695I29.7Very low34.7Very low169 Ų169130.8 Ų130.887%0.86769%0.69SS**  trans-55105167.1-63.6167.1000105.7P693 A697P693-I695 PolarHBondContact O-N 3.43Å; I695-A697 PolarHBondContact O-N 3.44Å
696F37.4Very low35.8Very low186 Ų186123.8 Ų123.882%0.81667%0.67SS**  trans-58.3126.6-179.7-84-95.4000108.8K694 K698K694-F696 WeakPolarHBondContact O-CD2 3.44Å; K694-F696 PolarHBondContact O-N 3.49Å; F696-K698 PolarHBondContact O-N 2.92Å
697A34Very low37Very low102 Ų102120 Ų12084%0.84365%0.654SS**  trans-61.2110.3173.500000108I695I695-A697 PolarHBondContact O-N 3.44Å
698K39.4Very low37.8Very low153 Ų153126 Ų12667%0.66566%0.655SS**  trans-57.4139.9172.8-72.6-172.3179.4-178.60109.2F696 E702F696-K698 PolarHBondContact O-N 2.92Å; K698-E702 VanDerWaalsContact CA-OE2 3.28Å; K698-E702 WeakPolarHBondContact CA-OE2 3.45Å; K698-E702 HydrophobicContact CB-CB 3.91Å; K698-E702 WeakPolarHBondContact CB-OE2 3.4Å; K698-E702 HydrophobicContact CD-CB 4.46Å; K698-E702 WeakPolarHBondContact CG-OE2 3.34Å
699S48.7Very low38.8Very low60 Ų60116.7 Ų116.742%0.4262%0.622SS.*  trans-56.8152179.665.20000110.9A701 E702 N703S699-A701 PolarHBondContact O-N 3Å; S699-A701 VanDerWaalsContact O-N 3.08Å; S699-E702 PolarHBondContact N-OE2 3.49Å; S699-E702 WeakPolarHBondContact O-CA 3.39Å; S699-E702 WeakPolarHBondContact O-CB 3.44Å; S699-E702 PolarHBondContact O-N 2.67Å; S699-N703 PolarHBondContact O-N 3.04Å; S699-N703 VanDerWaalsContact O-N 3.07Å
700E44Very low39.6Very low164 Ų164114.7 Ų114.777%0.76661%0.613SS**Hα-helixtrans-53.9-33.6-177.7-161.4171.5-167.100112.6N703 I704E700-N703 WeakPolarHBondContact O-CA 3.22Å; E700-N703 WeakPolarHBondContact O-CB 3.32Å; E700-N703 PolarHBondContact O-N 3.4Å; E700-N703 VanDerWaalsContact O-N 3.13Å; E700-I704 WeakPolarHBondContact O-CG1 3.3Å; E700-I704 PolarHBondContact O-N 3.42Å
701A47.9Very low40.3Very low47 Ų47110.5 Ų110.539%0.38859%0.589SS.*Hα-helixtrans-65.9-39.717300000113.9S699 N703 I704 A705S699-A701 PolarHBondContact O-N 3Å; S699-A701 VanDerWaalsContact O-N 3.08Å; A701-N703 PolarHBondContact O-N 3.26Å; A701-I704 PolarHBondContact O-N 3.47Å; A701-A705 PolarHBondContact O-N 3.48Å
702E50.7Low41Very low59 Ų59110.7 Ų110.728%0.27659%0.59SS.*Hα-helixtrans-65.2-28.9170.9-74.6-177.1140.500111.4K698 S699 G706K698-E702 VanDerWaalsContact CA-OE2 3.28Å; K698-E702 WeakPolarHBondContact CA-OE2 3.45Å; K698-E702 HydrophobicContact CB-CB 3.91Å; K698-E702 WeakPolarHBondContact CB-OE2 3.4Å; K698-E702 HydrophobicContact CD-CB 4.46Å; K698-E702 WeakPolarHBondContact CG-OE2 3.34Å; S699-E702 PolarHBondContact N-OE2 3.49Å; S699-E702 WeakPolarHBondContact O-CA 3.39Å; S699-E702 WeakPolarHBondContact O-CB 3.44Å; S699-E702 PolarHBondContact O-N 2.67Å; E702-G706 PolarHBondContact O-N 2.78Å
703N51Low41.5Very low105 Ų105117.7 Ų117.756%0.56160%0.602SS**Hα-helixtrans-71.6-38.3176.1-1365.2000111.6S699 E700 A701 G706 T707S699-N703 PolarHBondContact O-N 3.04Å; S699-N703 VanDerWaalsContact O-N 3.07Å; E700-N703 WeakPolarHBondContact O-CA 3.22Å; E700-N703 WeakPolarHBondContact O-CB 3.32Å; E700-N703 PolarHBondContact O-N 3.4Å; E700-N703 VanDerWaalsContact O-N 3.13Å; A701-N703 PolarHBondContact O-N 3.26Å; N703-G706 CarbonylContact O-C 3.29Å; N703-G706 PolarHBondContact O-N 3.35Å; N703-T707 PolarHBondContact O-N 2.7Å; N703-T707 PolarHBondContact O-OG1 2.88Å
704I44.6Very low41.7Very low109 Ų109118 Ų11856%0.55959%0.593SS**Hα-helixtrans-63.4-48.7174.6-64.8167.3000110.8E700 A701 G706 T707 Y708E700-I704 WeakPolarHBondContact O-CG1 3.3Å; E700-I704 PolarHBondContact O-N 3.42Å; A701-I704 PolarHBondContact O-N 3.47Å; I704-G706 VanDerWaalsContact C-N 3.3Å; I704-G706 PolarHBondContact O-N 3.1Å; I704-T707 WeakPolarHBondContact O-CB 3.35Å; I704-T707 PolarHBondContact O-N 2.87Å; I704-Y708 PolarHBondContact O-N 3.28Å
705A48Very low42.2Very low13 Ų13119.5 Ų119.511%0.10759%0.594CS.*Hα-helixtrans-60.3-41.817400000111.3I561 A701 T707 Y708 F709I561-A705 HydrophobicContact CD1-CB 4.21Å; A701-A705 PolarHBondContact O-N 3.48Å; A705-T707 PolarHBondContact O-N 2.88Å; A705-T707 VanDerWaalsContact O-N 3.17Å; A705-Y708 PolarHBondContact O-N 3.15Å; A705-F709 HydrophobicContact CB-CD2 4.41Å; A705-F709 WeakPolarHBondContact O-CD2 3.39Å; A705-F709 PolarHBondContact O-N 3.12Å; A705-F709 VanDerWaalsContact O-N 3.08Å
706G47.1Very low42.3Very low39 Ų39117.5 Ų117.540%0.40259%0.585SS.*Hα-helixtrans-62-19.7174.200000114.6E702 N703 I704 K710E702-G706 PolarHBondContact O-N 2.78Å; N703-G706 CarbonylContact O-C 3.29Å; N703-G706 PolarHBondContact O-N 3.35Å; I704-G706 VanDerWaalsContact C-N 3.3Å; I704-G706 PolarHBondContact O-N 3.1Å; G706-K710 WeakPolarHBondContact O-CG 3.39Å
707T49.7Very low42.4Very low89 Ų89115 Ų11555%0.54658%0.584SS.*Hα-helixtrans-91.3-39177.9-470000111.6N703 I704 A705N703-T707 PolarHBondContact O-N 2.7Å; N703-T707 PolarHBondContact O-OG1 2.88Å; I704-T707 WeakPolarHBondContact O-CB 3.35Å; I704-T707 PolarHBondContact O-N 2.87Å; A705-T707 PolarHBondContact O-N 2.88Å; A705-T707 VanDerWaalsContact O-N 3.17Å
708Y43.4Very low42.1Very low200 Ų200114.3 Ų114.378%0.78458%0.579SS**Hα-helixtrans-69-33177.3-123-90.6000112.9I704 A705I704-Y708 PolarHBondContact O-N 3.28Å; A705-Y708 PolarHBondContact O-N 3.15Å
709F41.5Very low41.7Very low63 Ų63111.3 Ų111.328%0.27658%0.578SS.*THydrogen-bonded Turntrans-106.328.3-174.9-62.7-69.5000113.6F550 Y557 A705 P711F550-F709 HydrophobicContact CE2-CD1 4.25Å; F550-F709 HydrophobicContact CZ-CB 3.86Å; F550-F709 HydrophobicContact CZ-CD1 4.2Å; F550-F709 VanDerWaalsContact CZ-O 3.32Å; F550-F709 WeakPolarHBondContact CZ-O 3.27Å; Y557-F709 HydrophobicContact CD2-CE1 4.07Å; Y557-F709 HydrophobicContact CD2-CE2 4.43Å; Y557-F709 AromaticContact CD2-CZ 3.78Å; Y557-F709 HydrophobicContact CD2-CZ 3.78Å; Y557-F709 HydrophobicContact CE2-CE1 4.11Å; Y557-F709 HydrophobicContact CE2-CZ 4.09Å; Y557-F709 HydrophobicContact CG-CZ 4.37Å; A705-F709 HydrophobicContact CB-CD2 4.41Å; A705-F709 WeakPolarHBondContact O-CD2 3.39Å; A705-F709 PolarHBondContact O-N 3.12Å; A705-F709 VanDerWaalsContact O-N 3.08Å; F709-P711 WeakPolarHBondContact O-CD 3.34Å
710K44Very low40.8Very low152 Ų152115.3 Ų115.366%0.66160%0.6SS**  trans-70.4114.3170-71.6-171.5179.81690108.7G706G706-K710 WeakPolarHBondContact O-CG 3.39Å
711P39.9Very low40Very low58 Ų58114.2 Ų114.238%0.37760%0.604SS.*  trans-61.1144.6168.123.7-27.7000108.9Y547 F550 F709 R713Y547-P711 HydrophobicContact CE1-CB 3.83Å; Y547-P711 HydrophobicContact CE1-CG 4.22Å; F550-P711 HydrophobicContact CE1-CB 4.49Å; F550-P711 HydrophobicContact CE1-CG 4.4Å; F709-P711 WeakPolarHBondContact O-CD 3.34Å; P711-R713 PolarHBondContact O-N 3.27Å
712L40.6Very low39.1Very low165 Ų165115.3 Ų115.386%0.86462%0.62SS**  trans-51.7112166.7-77.6159.5000107.2Q714L712-Q714 PolarHBondContact O-N 3.06Å
713R35.9Very low38.1Very low238 Ų238121 Ų12190%0.89865%0.647SS**  trans-55.2128.8174.8-83.3-175.6175.9-177.8-1.5107.9P711 R715P711-R713 PolarHBondContact O-N 3.27Å; R713-R715 PolarHBondContact O-N 2.9Å
714Q32.2Very low37Very low132 Ų132127.4 Ų127.462%0.61766%0.663SS**  trans-49.9114.4164.1-87.6176.1-32.200107.7L712 N716L712-Q714 PolarHBondContact O-N 3.06Å; Q714-N716 PolarHBondContact O-N 3.1Å
715R37Very low36.3Very low207 Ų207125.6 Ų125.678%0.78167%0.671SS**  trans-68.2115.6155.7-77.3-176.9179.2168.8-0.7104.4R713 V717R713-R715 PolarHBondContact O-N 2.9Å; R715-V717 HydrophobicContact CB-CG2 3.86Å; R715-V717 PolarHBondContact O-N 2.85Å
716N30.5Very low35.6Very low127 Ų127135.2 Ų135.268%0.67971%0.706SS**  trans-6485.6165.4-75.8-15.8000107.4Q714 A718Q714-N716 PolarHBondContact O-N 3.1Å; N716-A718 PolarHBondContact O-N 3.3Å; N716-A718 VanDerWaalsContact O-N 3.13Å
717V39.5Very low35.3Very low132 Ų132136.7 Ų136.780%0.871%0.71SS**  trans-86.159.4170.9-169.60000107.3R715R715-V717 HydrophobicContact CB-CG2 3.86Å; R715-V717 PolarHBondContact O-N 2.85Å
718A29.2Very low35.1Very low89 Ų89136 Ų13674%0.73671%0.705SS**  trans159.384.4161.800000110.3N716N716-A718 PolarHBondContact O-N 3.3Å; N716-A718 VanDerWaalsContact O-N 3.13Å
719S29.6Very low35.3Very low90 Ų90130.1 Ų130.163%0.62969%0.691SS**  trans-153.955.6148.969.50000108.9
720T29.9Very low35.6Very low144 Ų144136.1 Ų136.188%0.88371%0.712SS**  trans-103.170.9167.348.30000108.6
721T29Very low35.7Very low140 Ų140134 Ų13486%0.85970%0.704SS**  trans-122.4101.3157.248.70000105.9
722G28Very low35.9Very low70 Ų70134 Ų13472%0.72270%0.699SS**SBendtrans126.290.4172.600000114.7
723E28.6Very low36.3Very low180 Ų180132 Ų13284%0.84169%0.689SS**SBendtrans57.2112.9143.5-57.8-168153.400121.3
724R29.5Very low36.8Very low239 Ų239128.1 Ų128.190%0.90268%0.681SS**  trans57.775.7153.8-61.7-170.6-134.9-159.73.2117.6
725G30.2Very low37.6Very low70 Ų70128 Ų12872%0.72268%0.684SS**  trans-151.398.115200000109.4S727G725-S727 PolarHBondContact O-N 2.93Å
726Y32Very low37.6Very low216 Ų216121.5 Ų121.585%0.84768%0.682SS**  trans-63103.4174-70.7-85.1000108.6T728Y726-T728 PolarHBondContact O-N 2.87Å
727S41.2Very low37.9Very low69 Ų69118.8 Ų118.848%0.48367%0.67SS.*  trans-73.5105.8174.7178.10000108.8G725 T729 W730G725-S727 PolarHBondContact O-N 2.93Å; S727-T729 PolarHBondContact O-N 2.93Å; S727-T729 VanDerWaalsContact O-N 3.1Å; S727-T729 PolarHBondContact OG-OG1 2.85Å; S727-W730 PolarHBondContact O-N 3.23Å
728T45.2Very low37.9Very low74 Ų74119.3 Ų119.345%0.45467%0.667SS.*Hα-helixtrans-54.1-27179.647.60000112.9Y726 W730 Q731 H732Y726-T728 PolarHBondContact O-N 2.87Å; T728-W730 VanDerWaalsContact C-N 3.29Å; T728-W730 PolarHBondContact O-N 2.76Å; T728-Q731 PolarHBondContact O-N 3.25Å; T728-H732 PolarHBondContact O-CD2 2.99Å; T728-H732 PolarHBondContact O-N 3.49Å; T728-H732 VanDerWaalsContact O-N 3.12Å
729T47.8Very low38.4Very low77 Ų77121.8 Ų121.847%0.47266%0.658SS.*Hα-helixtrans-55.6-36.9179.7-15.20000114.2S727 L733S727-T729 PolarHBondContact O-N 2.93Å; S727-T729 VanDerWaalsContact O-N 3.1Å; S727-T729 PolarHBondContact OG-OG1 2.85Å; T729-L733 PolarHBondContact O-N 3.21Å
730W47.4Very low38.9Very low189 Ų189122.4 Ų122.472%0.71666%0.659SS**Hα-helixtrans-75.4-34.3-179.2-97.7106.7000112.9S727 T728 L733 Q734S727-W730 PolarHBondContact O-N 3.23Å; T728-W730 VanDerWaalsContact C-N 3.29Å; T728-W730 PolarHBondContact O-N 2.76Å; W730-L733 PolarHBondContact O-N 2.92Å; W730-Q734 PolarHBondContact O-N 3.25Å
731Q46.5Very low39.3Very low109 Ų109121.6 Ų121.651%0.50965%0.649SS.*Hα-helixtrans-70-34.9175.1-79.9174.7-26.100111.8T728 L733 Q734 N735T728-Q731 PolarHBondContact O-N 3.25Å; Q731-L733 VanDerWaalsContact C-N 3.32Å; Q731-L733 PolarHBondContact O-N 3.02Å; Q731-Q734 PolarHBondContact O-N 3.27Å; Q731-N735 PolarHBondContact O-N 2.9Å
732H44.2Very low39.9Very low56 Ų56118.6 Ų118.626%0.25963%0.627SS.*Hα-helixtrans-68.7-34.3178.5-71.2-149.5000111.4T728 N735 G736 D742T728-H732 PolarHBondContact O-CD2 2.99Å; T728-H732 PolarHBondContact O-N 3.49Å; T728-H732 VanDerWaalsContact O-N 3.12Å; H732-N735 PolarHBondContact O-N 2.67Å; H732-G736 PolarHBondContact O-N 3.3Å; H732-D742 IonicContact CE1-OD2 3.41Å; H732-D742 PolarHBondContact CE1-OD2 3.38Å; H732-D742 IonicContact CG-OD2 3.3Å; H732-D742 IonicContact ND1-OD2 3.77Å; H732-D742 PolarHBondContact ND1-OD2 3.45Å
733L48.1Very low40.5Very low125 Ų125119.9 Ų119.965%0.65462%0.618SS**Hα-helixtrans-67.6-35.3174.8-115.9146.1000113T729 W730 Q731T729-L733 PolarHBondContact O-N 3.21Å; W730-L733 PolarHBondContact O-N 2.92Å; Q731-L733 VanDerWaalsContact C-N 3.32Å; Q731-L733 PolarHBondContact O-N 3.02Å
734Q48Very low40.8Very low156 Ų156120.5 Ų120.573%0.72961%0.613SS**Hα-helixtrans-72.2-29.2175.2-77.2-176.3-34.100113.1W730 Q731W730-Q734 PolarHBondContact O-N 3.25Å; Q731-Q734 PolarHBondContact O-N 3.27Å
735N47.4Very low41Very low128 Ų128114 Ų11468%0.68461%0.611SS**THydrogen-bonded Turntrans-95.83.9-176.2-69.3-12.7000114.2Q731 H732 V737Q731-N735 PolarHBondContact O-N 2.9Å; H732-N735 PolarHBondContact O-N 2.67Å; N735-V737 PolarHBondContact O-N 3.21Å
736G36.9Very low41Very low71 Ų71114.5 Ų114.573%0.73262%0.616SS**THydrogen-bonded Turntrans68.712.7171.100000115.8H732H732-G736 PolarHBondContact O-N 3.3Å
737V37.7Very low40.8Very low71 Ų71107.5 Ų107.543%0.4361%0.609SS.*  trans-121.8109.9-179.6-176.80000109.4N735 Y739N735-V737 PolarHBondContact O-N 3.21Å; V737-Y739 HydrophobicContact CB-CE2 4.44Å; V737-Y739 HydrophobicContact CG1-CD2 4.18Å; V737-Y739 HydrophobicContact CG1-CE1 4.34Å; V737-Y739 HydrophobicContact CG1-CE2 3.64Å
738L39.6Very low40.2Very low143 Ų143109 Ų10975%0.74962%0.62SS**  trans-90.6117.1171.7-94.5119.8000109.5
739Y39Very low39.5Very low140 Ų140115.2 Ų115.255%0.54964%0.644SS.*  trans-87.3131.3168.6-69.1-81.2000109.8V737 D741 D742V737-Y739 HydrophobicContact CB-CE2 4.44Å; V737-Y739 HydrophobicContact CG1-CD2 4.18Å; V737-Y739 HydrophobicContact CG1-CE1 4.34Å; V737-Y739 HydrophobicContact CG1-CE2 3.64Å; Y739-D741 PolarHBondContact O-N 3.43Å; Y739-D742 WeakPolarHBondContact O-CB 3.26Å; Y739-D742 PolarHBondContact O-N 3.27Å; Y739-D742 VanDerWaalsContact O-N 3.14Å
740T40Very low38.7Very low103 Ų103118 Ų11863%0.63266%0.655SS**THydrogen-bonded Turntrans-61.3-24.2-178.545.40000113D742 L743T740-D742 VanDerWaalsContact C-N 3.26Å; T740-D742 PolarHBondContact O-N 2.74Å; T740-L743 PolarHBondContact O-N 3Å
741D39.4Very low37.8Very low128 Ų128115.1 Ų115.168%0.68466%0.658SS**Hα-helixtrans-66.3-26.2177.8-67.7-23.4000113Y739 L743Y739-D741 PolarHBondContact O-N 3.43Å; D741-L743 PolarHBondContact O-N 2.94Å
742D40.7Very low37Very low76 Ų76120 Ų12041%0.40668%0.678SS.*Hα-helixtrans-69.9-17.2178-70.6-29.9000112.7H732 Y739 T740H732-D742 IonicContact CE1-OD2 3.41Å; H732-D742 PolarHBondContact CE1-OD2 3.38Å; H732-D742 IonicContact CG-OD2 3.3Å; H732-D742 IonicContact ND1-OD2 3.77Å; H732-D742 PolarHBondContact ND1-OD2 3.45Å; Y739-D742 WeakPolarHBondContact O-CB 3.26Å; Y739-D742 PolarHBondContact O-N 3.27Å; Y739-D742 VanDerWaalsContact O-N 3.14Å; T740-D742 VanDerWaalsContact C-N 3.26Å; T740-D742 PolarHBondContact O-N 2.74Å
743L41Very low36Very low98 Ų98128.7 Ų128.751%0.51371%0.709SS.*Hα-helixtrans-93.9-20.4-177.2-71.9166.1000113.7T740 D741T740-L743 PolarHBondContact O-N 3Å; D741-L743 PolarHBondContact O-N 2.94Å
744Y36.2Very low35.1Very low192 Ų192132.2 Ų132.275%0.75372%0.719SS**Hα-helixtrans-127.113.9-165.3-67.8-77.6000115.7G746Y744-G746 PolarHBondContact O-N 3.39Å
745A33.4Very low34.1Very low103 Ų103130.4 Ų130.485%0.85172%0.721SS**  trans-69.177.3172.500000112.2
746G30.3Very low33.2Very low81 Ų81130.3 Ų130.384%0.83573%0.729SS**  trans-151.414.1177.900000114.6Y744Y744-G746 PolarHBondContact O-N 3.39Å
747G27.3Very low32.8Very low68 Ų68135 Ų13570%0.70174%0.736SS**SBendtrans-117.5128.8175.600000111.8
748S29.1Very low32.4Very low100 Ų100139.6 Ų139.670%0.69976%0.757SS**  trans68.382.7165.8175.50000117.3L750S748-L750 PolarHBondContact O-N 3.39Å; S748-L750 VanDerWaalsContact O-N 3.12Å
749Q30.1Very low31.8Very low205 Ų205136.3 Ų136.396%0.95876%0.758SS**  trans-76.773.7148.9-73.7-166.5-3.300109.8
750L29.6Very low31.4Very low135 Ų135134 Ų13471%0.70777%0.767SS**SBendtrans-121.9100.2160.1-90.2157.8000107.3S748S748-L750 PolarHBondContact O-N 3.39Å; S748-L750 VanDerWaalsContact O-N 3.12Å
751T29.1Very low30.7Very low129 Ų129136.7 Ų136.779%0.79178%0.778SS**  trans44.875.2156.364.60000117.4
752K29.2Very low30.4Very low212 Ų212140.1 Ų140.192%0.92279%0.787SS**  trans-89.7102.8152.8-78.9-172.8178.3179.60108.8K754K752-K754 PolarHBondContact O-N 3.26Å
753R24.8Very low29.9Very low239 Ų239140.9 Ų140.990%0.90280%0.798SS**PPolyproline II helixtrans-54.2132.6170.9-74.4-177.7171.4-174.7-2.1109.1
754K29.1Very low29.3Very low198 Ų198143.4 Ų143.486%0.86181%0.813SS**PPolyproline II helixtrans-54.6134.9174.3-79.9-179.4173.81800109.9K752 C756K752-K754 PolarHBondContact O-N 3.26Å; K754-C756 PolarHBondContact O-N 2.63Å
755P26.9Very low29Very low119 Ų119145.9 Ų145.977%0.77382%0.821SS**PPolyproline II helixtrans-68.8127.8174.5-6.421.4000109.3L757P755-L757 PolarHBondContact O-N 3.03Å
756C26.7Very low29.1Very low126 Ų126146.6 Ų146.685%0.85182%0.816SS**  trans-71.3113.5169.3-147.10000107.4K754 L758K754-C756 PolarHBondContact O-N 2.63Å; C756-L758 PolarHBondContact O-N 3.07Å; C756-L758 VanDerWaalsContact O-N 3.1Å
757L30Very low29Very low168 Ų168147.3 Ų147.388%0.8881%0.808SS**  trans-70.3102.5174.4-84.1159.2000108.7P755 G759P755-L757 PolarHBondContact O-N 3.03Å; L757-G759 PolarHBondContact O-N 3.38Å; L757-G759 VanDerWaalsContact O-N 3.11Å
758L28.4Very low29.3Very low169 Ų169150.2 Ų150.289%0.88582%0.815SS**  trans-62.8103.8160.6-90.3148.1000107.7C756 A760C756-L758 PolarHBondContact O-N 3.07Å; C756-L758 VanDerWaalsContact O-N 3.1Å; L758-A760 PolarHBondContact O-N 3.21Å
759G27.3Very low29.2Very low74 Ų74153 Ų15376%0.76382%0.822SS**  trans-64.2103.3175.200000110.4L757L757-G759 PolarHBondContact O-N 3.38Å; L757-G759 VanDerWaalsContact O-N 3.11Å
760A30.3Very low29.3Very low90 Ų90152.3 Ų152.374%0.74484%0.84SS**  trans-88.7119166.200000109L758 F762L758-A760 PolarHBondContact O-N 3.21Å; A760-F762 PolarHBondContact O-N 3.07Å
761N26.5Very low29.2Very low161 Ų161153.2 Ų153.286%0.86185%0.847SS**  trans-49.1122.3176.3-69.4-46.7000112.8
762F32.7Very low29.2Very low200 Ų200154.5 Ų154.588%0.87785%0.85SS**  trans-111.4101.8150.5-93.6-83.7000109.3A760A760-F762 PolarHBondContact O-N 3.07Å
763S30.2Very low29.2Very low91 Ų91151.3 Ų151.364%0.63685%0.846SS**  trans-16.2133.4156.853.40000118.6
764N27Very low29.5Very low152 Ų152146.1 Ų146.181%0.81384%0.842SS**  40.8114.5128.5-69.2-15.2000118.9
765R31.3Very low29.5Very low244 Ų244142.9 Ų142.992%0.92184%0.841SS**  -167.2151.6107.7-102.4173.2-167.8-133.74.2112.4
766P34.4Very low29.7Very low117 Ų117144.5 Ų144.576%0.7685%0.846SS**PPolyproline II helixtrans-97.6163.3-158.837.9-33000114.3
767S27.8Very low29.9Very low96 Ų96145.8 Ų145.867%0.67185%0.845SS**PPolyproline II helixtrans-55.9142.4170.649.10000113.9
768P35.5Very low29.9Very low130 Ų130144.1 Ų144.184%0.84484%0.843SS**PPolyproline II helixtrans-85.3122.316332.5-25.5000109.9
769N25.6Very low30Very low158 Ų158142 Ų14285%0.84584%0.839SS**PPolyproline II helixtrans-77.2121.8162-81.7-21.2000109.2
770S31.9Very low30.3Very low191 Ų191148.2 Ų148.2100%1.33685%0.846SS**  trans179.2013165.50000108.7

Retrieved 770 of 770 residues in 288.9 ms (Link to these results)